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Archive, 2024-11

2 The dynamics of capillary flow in an open-channel system featuring trigger valves
Tokihiro, J. C.; Robertson, I. H.; Gregucci, D.; Shin, A.; Michelini, E.; Nicholson, T. M.; Olanrewaju, A.; Theberge, A. B.; Berthier, J.; Berthier, E.
10.1101/2024.09.17.613325 — bioengineering — Posted on 2024-11-30
3 The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-proteinaceous substrates in vitro
Wang, X.; Jiou, J.; Cerra, A.; Cobbold, S. A.; Jochem, M.; Mak, K. H. T.; Corcilius, L.; Payne, R. J.; Goddard-Borger, E. D.; Komander, D.; Lechtenberg, B. C.
10.1101/2024.11.29.626046 — biochemistry — Posted on 2024-11-30
4 Computer-guided design of Z domain peptides with improved inhibition of VEGF
Geist, C.; Useini, A.; Kazimir, A.; Kuempfel, R.; Meiler, J.; Lamers, C.; Kalkhof, S.; Kuenze, G.
10.1101/2024.11.29.626075 — biochemistry — Posted on 2024-11-30
7 TTF2 promotes replisome eviction from stalled forks in mitosis
Can, G.; Shyian, M.; Krishnamoorthy, A.; Lim, Y.; Wu, A.; Zaher, M.; Raeschle, M.; Walter, J.; Pellman, D.
10.1101/2024.11.30.626186 — biochemistry — Posted on 2024-11-30
8 Efficient synthesis of arabinosyl nucleosides via active site engineering of the Leishmania mexicana purine 2'-deoxyribosyltranferase
Cecchini, D. A.; Acosta, J.; Saiz-Alvarez, L. P.; Ortega, C.; Kaminski, P. A.; Fernandez-Lucas, J.; Hidalgo, A.
10.1101/2024.11.29.626018 — biochemistry — Posted on 2024-11-30
9 Sortase A-mediated farnesylation of Cdc42 in vitro
Tschirpke, S.; Hettema, N. M.; Spitzbarth, B.; Eelkema, R.; Laan, L.
10.1101/2024.11.29.626060 — biochemistry — Posted on 2024-11-30
14 Intact messenger RNA exists in human blood plasma and urine, and their purified macromolecular compartments
Verwilt, J.; Verniers, K.; De Geyter, S.; Roelandt, S.; Pinheiro, C.; Hendrix, A.; Mestdagh, P.; Vandesompele, J.
10.1101/2024.11.30.626091 — molecular biology — Posted on 2024-11-30
15 Dysregulated RNA splicing induces regeneration failure in alcohol-associated liver disease
Chembazhi, U. V.; Bangru, S.; Dutta, R.; Das, D.; Peiffer, B.; Natua, S.; Toohill, K.; Leona, A.; Purwar, I.; Bhowmik, A.; Goyal, Y.; Sun, Z.; Diehl, A. M.; Kalsotra, A.
10.1101/2024.11.29.626099 — molecular biology — Posted on 2024-11-30
17 Influenza A virus-induced production of PI4P at the endoplasmic reticulum involves ATG16L1 and promotes the egress of viral ribonucleoproteins
Alemany, C.; Da Graca, J.; Giai Gianetto, Q.; Paisant, S.; Dupont, M.; Douche, T.; Isel, C.; Delevoye, C.; Danglot, L.; Matondo, M.; Morel, E.; Brault, J.-B.; Naffakh, N.
10.1101/2024.11.29.625996 — microbiology — Posted on 2024-11-30
18 Whole Virion Proteomics of HCMV Reveals that gpUL141 is a Virion Component that Regulates Envelope Glycoprotein Composition to Protect Against Humoral Immunity
Bentley, K.; Statkute, E.; Murrell, I.; Fielding, C.; Antrobus, R.; Preston, H.; Kerr, L.; Cochrane, D.; Brizic, I.; Lehner, P. J.; Wilkinson, G. W.; Wang, E. C. Y.; Graham, S. C.; Weekes, M. P.; Stanton, R. J.
10.1101/2024.11.29.626001 — microbiology — Posted on 2024-11-30
22 Protection against N. gonorrhoeae induced by OMV-based Meningococcal Vaccines are associated with cross-species directed humoral and cellular immune responses
Zhu, W.; Waltmann, A.; Little, M.; Connolly, K. L.; Matthias, K. A.; Thomas, K. S.; Gray, M. C.; Sikora, A. E.; Criss, A. K.; Bash, M. C.; Macintyre, A. N.; Jerse, A. E.; Duncan, J. A.
10.1101/2024.11.29.626107 — microbiology — Posted on 2024-11-30
25 Flavivirus NS1-triggered endothelial dysfunction promotes virus dissemination
Puerta-Guardo, H.; Biering, S. B.; Castillo-Rojas, B.; DiBiasio-White, M. J.; Lo, N. T.; Espinosa, D. A.; Warnes, C. M.; Wang, C.; Cao, T.; Glasner, D. R.; Beatty, P. R.; Kuhn, R. J.; Harris, E.
10.1101/2024.11.29.625931 — microbiology — Posted on 2024-11-30
26 A dual role in virion attachment and entry makes the human cytomegalovirus gHgLgO trimer the central player in virion infectivity
Thiessen, L.; Garuti, R.; Kubic, L.; Koesters, M.; Amarambedu Selvakumar, D.; Krey, T.; Goerzer, I.; Froehlich, T.; Adler, B.
10.1101/2024.11.29.625639 — microbiology — Posted on 2024-11-30
28 Age is an intrinsic driver of inflammatory responses to malaria
Loughland, J.; Dooley, N.; Pava, Z.; SheelaNair, A.; Andrew, D.; Tipping, P.; Bourke, P.; Engwerda, C.; Lopez, J. A.; Piera, K.; William, T.; Barber, B.; Grigg, M.; Anstey, N.; Minigo, G.; Boyle, M. J.
10.1101/2024.11.26.625574 — immunology — Posted on 2024-11-30
29 Defining and Controlling Axial Nephron Patterning in Human Kidney Organoids with Synthetic Wnt-Secreting Organizers
Fausto, C. C.; Glykofrydis, F.; Kumar, N.; Schnell, J.; Csipan, R. L.; De Kuyper, F.; Grubbs, B.; Thornton, M.; Achieng, M.; Morsut, L.; Lindstrom, N. O.
10.1101/2024.11.30.626171 — synthetic biology — Posted on 2024-11-30
31 Structure-function relationships of mucociliary clearance in the human airways
Roth, D.; Sahin, A. T.; Ling, F.; Tepho, N.; Senger, C.; Quiroz, E.; Calvert, B.; van der Does, A.; Güney, T. G.; Glasl, S.; van Schadewijk, A.; von Schledorn, L.; Olmer, R.; Kanso, E.; Nawroth, J. C.; Ryan, A. L.
10.1101/2023.12.24.572054 — biophysics — Posted on 2024-11-30
33 The proteotranscriptomic characterization of venom in the white seafan Eunicella singularis elucidates the evolution of Octocorallia arsenal
Modica, M. V.; Leone, S.; Gerdol, M.; Greco, S.; AURELLE, D.; Fassio, G.; Oliverio, M.; El Koulali, K.; Barrachina, C.; Dutertre, S.
10.1101/2024.05.31.596435 — evolutionary biology — Posted on 2024-11-30
37 Hypoxia inhibits newt skeletal muscle dedifferentiation
Vdovin, G.; Walters, H.; Troianovskyi, K.; Tsuchiya, Y.; Yun, M.
10.1101/2024.11.29.626015 — developmental biology — Posted on 2024-11-30
42 Early changes in the properties of CA3 engram cells explored with a novel viral tool
Cupolillo, D.; Grosjean, N.; Marneffe, C.; Viotti, J.; Reynaud, C.; Deforges, S.; Carta, M.; Mulle, C.
10.1101/2024.11.29.625977 — neuroscience — Posted on 2024-11-30
46 Dual-acting gene therapy targeting HIF1A and HIF2A by RNA interference mitigates retinal degeneration in two mouse models of AMD
Ebner, L. J. A.; Imsand, C.; Karademir, D.; Peters, F.; Kiessling, E.; Fottner, A.; Matter, C.; Fajardo, D. S.; Merolla, L.; Woegenstein, G. M.; Tsioti, I.; Govers, L. P.; Blaser, F.; Meneau, I.; Boye, S. L.; Boye, S. E.; Grimm, C.; Samardzija, M.
10.1101/2024.11.29.626080 — neuroscience — Posted on 2024-11-30
48 Deep learning super-resolution of paediatric ultra-low-field MRI without paired high-field scans
Briski, U.; Bourke, N. J.; Donald, K. A.; Bradford, L. E.; Williams, S. R.; Zieff, M. R.; Deoni, S. C. L.; Williams, S. C. R.; South Africa Study Team, K.; Moran, R. J.; Baljer, L.; Vasa, F.
10.1101/2024.11.29.625898 — neuroscience — Posted on 2024-11-30
56 Characterization and Functional Assessment of Epicardial Secretome: Epicardium-Derived Extracellular Vesicles and Matrix
Oliveira, C. C.; Cordoba, J.; Pearson, J.; Guruceaga, E.; Marin-Sedeno, E.; Garcia-Caballero, M.; Guadix, J. A.; Perez-Pomares, J. M.; Ruiz-Villalba, A.
10.1101/2024.11.29.626089 — developmental biology — Posted on 2024-11-30
57 Intragenomic variants of a putative effector drive early-stage infection in a broad host-range rust fungus
Degnan, R.; Sawyer, A.; Gardiner, D.; Luo, Z.; Frampton, R.; Schwessinger, B.; Mitter, N.; Carroll, B.; Smith, G.; McTaggart, A.; Shuey, L.
10.1101/2024.11.28.625939 — microbiology — Posted on 2024-11-30
59 Intestinal Dysbiosis Alters Acute Seizure Burden and Antiseizure Medicine Activity in the Theiler's Virus Model of Encephalitis
Erickson, I.; Davidson, S.; Choi, H.; Rho, S.; Guignet, M.; Peagler, K.; Thummel, K.; Ericsson, A. C.; Barker-Haliski, M.
10.1101/2024.11.29.625527 — neuroscience — Posted on 2024-11-30
60 Nonequilibrium dynamics elicited as the origin of perturbative complexity
Stikvoort, W.; Perez-Ordoyo, E.; Mindlin, I.; Escrichs, A.; Sitt, J. D.; Kringelbach, M. L.; Deco, G.; Sanz Perl, Y.
10.1101/2024.11.29.625885 — neuroscience — Posted on 2024-11-30
62 Dissecting the differential role of C-terminal truncations in the regulation of aSyn pathology formation and the biogenesis of Lewy bodies
Mahul-Mellier, A.-L.; Altay, M. F.; Maharjan, N.; Ait-Bouziad, N.; Chiki, A.; Jagannath, S.; Limorenko, G.; Novello, S.; Ricci, J.; Vingill, S.; Wade-Martins, R.; Holton, J.; Strand, C.; Haikal, C.; Li, J.-Y.; Hamelin, R.; Croisier, M.-C.; Knott, G.; Mairet-Coello, G.; Michel, A.; Downey, P.; Citron, M.; Lashuel, H. A.
10.1101/2024.11.29.625993 — neuroscience — Posted on 2024-11-30
65 Fate (or state) of CA2 neurons in a mineralocorticoid receptor knockout.
Harris, E. P.; Jones, S. M.; Alexander, G. M.; Kandemir, B.; Ward, J. M.; Wang, T.; Proano, S. B.; Xu, X.; Dudek, S. M.
10.1101/2024.11.29.626110 — neuroscience — Posted on 2024-11-30
66 Characterizing neuronal and population responses to electrical stimulation in the human hippocampo-cortical network
van der Plas, M.; Roux, F.; Chelvarajah, R.; Sawlani, V.; Staresina, B.; Wimber, M.; Rollings, D.; Hanslmayr, S.
10.1101/2024.11.28.625915 — neuroscience — Posted on 2024-11-30
67 NaDyNet: A Toolbox for Dynamic Network Analysis of Naturalistic Stimuli
Yang, J.; Hu, Z.; Li, J.; Guo, X.; Gao, X.; Liu, J.; Wang, Y.; Qu, Z.; Li, W.; Li, Z.; Li, W.; Huang, Y.; Chen, J.; Wen, H.; Yuan, B.
10.1101/2024.11.29.626037 — neuroscience — Posted on 2024-11-30
68 A wide diversity of viruses detected in African mammals involved in the wild meat supply chain
Geraerts, M.; Gombeer, S.; Nebesse, C.; Akaibe, D.; Akaibe, D.; Baelo, P.; Chaber, A.-L.; Gembu, G.-C.; Gaubert, P.; Joffrin, L.; Laudisoit, A.; Laurent, N.; Leirs, H.; Mande, C.; Mariën, J.; Ngoy, S.; Tesikova, J.; Vanderheyden, A.; van Vredendaal, R.; Verheyen, E.; Gryseels, S.
10.1101/2024.11.28.625648 — genomics — Posted on 2024-11-30
71 Bidirectional control of neurovascular coupling by cortical somatostatin interneurons
Mohamed, B.; O Reilly, J.; Picaud, S.; Le Gac, B.; Belzic, E.; Castro, L. R.; Soula, H.; Dusart, I.; Li, D.; Cauli, B.
10.1101/2024.11.06.622247 — neuroscience — Posted on 2024-11-30
72 Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models
Lei, C.; Zhang, B.; Yamaguchi, J.; Tamura, R.; Cao, X.; Liu, Y.; Seki, M.; Suzuki, Y.; Suzuki, K.; Tanida, I.; Uchiyama, Y.; Hisatsune, T.
10.1101/2024.11.12.622892 — neuroscience — Posted on 2024-11-30
73 Enhanced Brain-Heart Connectivity as a Precursor of Reduced State Anxiety After Therapeutic Virtual Reality Immersion
Sezer, I.; Moreau, P.; El Sayed Hussein Jomaa, M.; Godefroy, V.; Batrancourt, B.; Levy, R.; Filipchuk, A.
10.1101/2024.11.28.625818 — neuroscience — Posted on 2024-11-30
78 Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
Marsh, N. M.; Macewen, M. J. S.; Chea, J.; Kenerson, H. L.; Kwong, A. A.; Locke, T. M.; Miralles, F. J.; Sapre, T.; Gozali, N. K.; Hart, M. L.; Bammler, T. K.; MacDonald, J.; Sullivan, L. B.; Atilla-Gokcumen, G. E.; Ong, S.-E.; Scott, J. D.; Yeung, R. S.; Sancak, Y.
10.1101/2024.05.27.596106 — cell biology — Posted on 2024-11-30
80 Amyloid signaling in antiphage defense
Ibarlosa, L.; Dheur, S.; Sanchez, C.; Deb, S.; Granger-Farbos, A.; Linares, V. C.; Berbon, M.; Massoni-Laporte, A.; Salin, B.; Blancard, C.; Saragaglia, C.; Tene, X. M.; Dufour, N.; Rossier, O.; Habenstein, B.; Debarbieux, L.; Kauffmann, B.; Loquet, A.; Saupe, S. J.
10.1101/2024.11.07.622273 — microbiology — Posted on 2024-11-30
81 Uncoupling the functional roles of Coronavirus Nsp1
Baeumlin, E.; Andenmatten, D.; Luginbuehl, J.; Lalou, A.; Schwaller, N.; Karousis, E. D.
10.1101/2024.08.05.606569 — molecular biology — Posted on 2024-11-30
82 Gamma Synchrony Mediates Figure-Ground Perception
Karimian, M.; Roberts, M. J.; De Weerd, P.; Senden, M.
10.1101/2024.11.29.626007 — neuroscience — Posted on 2024-11-30
84 Visual objects refine head direction coding
Siegenthaler, D.; Denny, H.; Skromne Carrasco, S.; Mayer, J. L.; Levenstein, D.; Peyrache, A.; Trenholm, S.; Mace, E.
10.1101/2024.10.21.619417 — neuroscience — Posted on 2024-11-30
86 Phage-mediated intercellular CRISPRi for biocomputation in bacterial consortia
Pujar, A.; Pathania, A.; Hopper, C.; Pandi, A.; Calderon, C. R.; Fugger, M.; Nowak, T.; Kushwaha, M.
10.1101/2024.09.02.610857 — synthetic biology — Posted on 2024-11-30
88 Advanced human cerebral organoids as a model for investigating glioma stem cell interactions with microglia and vascular cells and response to radiotherapy
Raguin, J.; Kortulewski, T.; Bergiers, O.; Granotier-Beckers, C.; Chatrousse, L.; Benchoua, A.; Gauthier, L. R.; Boussin, F. D.; Mouthon, M.-A.
10.1101/2024.11.28.625826 — cancer biology — Posted on 2024-11-30
92 Decoding the Variant-to-Function Relationship for LIPA, a Risk Locus for CAD
Li, F.; Flynn, E.; Ha, P.; Zebak, M. N.; Cheng, H.; Xue, C.; Shi, J.; Wu, X.; Wang, Z.; Meng, Y.; Cui, J.; Zhu, Y.; Rozenblyum, A.; Chun, J.; Hernandez-Ono, A.; Javaheri, A.; Razani, B.; Westerterp, M.; Bauer, R. C.; Suh, Y.; Hao, K.; Lappalainen, T.; Zhang, H.
10.1101/2022.11.12.516293 — genomics — Posted on 2024-11-30
96 Home range spillover in habitats with impassable boundaries: Causes, biases, and corrections using autocorrelated kernel density estimation
Hollins, J. P. W.; Fleming, C. H.; Calabrese, J.; Harris, L. N.; Moore, J.-S.; Malley, B. K.; Noonan, M. J.; Fagan, W. F.; Alston, J. M.; Hussey, N. E.
10.1101/2024.11.20.624379 — ecology — Posted on 2024-11-30
99 Genome scale identification of new genes using saturated reporter transposon mutagenesis
Goodall, E. C. A.; Hodges, F.; Kok, W.; Permana, B.; Cuddihy, T.; Yang, Z.; Kahler, N.; Shires, K.; Pullela, K.; Torres, V. V. L.; Rooke, J.; Delhaye, A.; Bryant, J. A.; Forde, B. M.; Hemm, M.; henderson, i.
10.1101/2024.09.06.611592 — microbiology — Posted on 2024-11-30
100 Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals
Zielinska, K.; Michalowska-Sawczyn, M.; Kosciolek, T.; Labaj, P. P.; Kochanowicz, A.; Mieszkowski, J.; Bicakci, B.; Proia, P.; Cieszczyk, P.; Huminska-Lisowska, K.
10.1101/2024.11.19.624295 — microbiology — Posted on 2024-11-30
102 Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus
Cole, J.; Raguideau, S.; Abbaszadeh-Dahaji, P.; Hilton, S.; Muscatt, G.; Mushinski, R. M.; Nilsson, R. H.; Ryan, M. H.; Quince, C.; Bending, G. D.
10.1101/2024.11.27.625642 — microbiology — Posted on 2024-11-30
104 Learning shapes neural geometry in the prefrontal cortex
Wojcik, M. J.; Stroud, J. P.; Wasmuht, D. F.; Kusunoku, M.; Kadohisa, M.; Buckley, M. J.; Myers, N. E.; Hunt, L. T.; Duncan, J.; Stokes, M. G.
10.1101/2023.04.24.538054 — neuroscience — Posted on 2024-11-30
105 Enabling Electric Field Model of Microscopically Realistic Brain
Qi, Z.; Noetscher, G. M.; Miles, A.; Weise, K.; Knosche, T.; Cadman, C. R.; Potashinsky, A. R.; Liu, K.; Wartman, W. A.; Nunez Ponasso, G. C.; Bikson, M.; Lu, H.; Deng, Z.-D.; Nummenmaa, A.; Makaroff, S. N.
10.1101/2024.04.04.588004 — neuroscience — Posted on 2024-11-30
106 A synthetic platform for multiplex screening of cell-cell communication between soil fungi
Schiesaro, G.; Jönsson, M.; Tenente, R.; Sorensen, M. B.; Wäneskog, M.; Undabarrena, A.; Deichmann, M.; Hoch-Schneider, E.; Kandasamy, V.; Frimurer, T. M.; Clemmensen, L. K. H.; Jensen, M. K.; Jensen, E. D.
10.1101/2024.10.30.620951 — synthetic biology — Posted on 2024-11-30
108 Concepts and methods for predicting viral evolution
Meijers, M.; Ruchnewitz, D.; Eberhardt, J.; Karmakar, M.; Łuksza, M.; Lässig, M.
10.1101/2024.03.19.585703 — biophysics — Posted on 2024-11-30
110 Healthy microbiome - moving towards functional interpretation
Zielinska, K.; Udekwu, K.; Rudnicki, W.; Frolova, A.; Labaj, P. P.
10.1101/2023.12.04.569909 — bioinformatics — Posted on 2024-11-30
111 Exploring SNP Filtering Strategies: The Influence of Strict vs Soft Core
Taouk, M. L.; Featherstone, L. A.; Taiaroa, G.; Seemann, T.; Ingle, D. J.; Stinear, T. P.; Wick, R. R.
10.1101/2024.08.26.609800 — genomics — Posted on 2024-11-29
112 Coordination of flux-related leaf and root traits impacts forest community assembly
Ma, Z.; Duan, M.; Sack, L.; Ma, C.; Li, L.; McCormack, M. L.; Lu, M.; Guo, D.
10.1101/2024.11.25.625305 — ecology — Posted on 2024-11-30
113 Revealing the diversity of commensal corynebacteria from a single human skin site
Herman, R.; Meaden, S.; Rudden, M.; Cornmell, R.; Wilkinson, A. J.; Murphy, B.; Thomas, G. H.
10.1101/2024.11.28.625817 — microbiology — Posted on 2024-11-30
114 A gene-expression module in circulating immune cells is associated with cell migration during immune diseases.
Sinha, D.; Laurent, T.; Broquet, A.; Fourgeux, C.; Letellier, T.; Tilly, G.; Bruneau, S.; Ville, S.; Bouchet-Delbos, L.; Branchereau, J.; Kerleau, C.; Brouard, S.; Blancho, G.; Giral, M.; Josien, R.; Danger, R.; Roquilly, A.; Degauque, N.; Poschmann, J.
10.1101/2023.04.11.536347 — immunology — Posted on 2024-11-30
118 Infection-on-Chip: an in vitro human vessel to study Neisseria meningitidis colonization and vascular damages
Pinon, L.; Chabaud, M.; Nivoit, P.; Wong-Ng, J.; Nguyen, T.-T.; Paul, V.; Bouquerel, C.; Goussard, S.; Frachon, E.; Obino, D.; Gobaa, S.; Dumenil, G.
10.1101/2024.02.09.579276 — synthetic biology — Posted on 2024-11-29
120 The Energetic Stress Marker GDF15 is Induced by Acute Psychosocial Stress
Huang, Q.; Monzel, A. S.; Rausser, S.; Haahr, R.; Devine, J.; Liu, C. C.; Kelly, C.; Thompson, E.; Kurade, M. S.; Michelson, J.; Li, S.; Engelstad, K.; Tanji, K.; Lauriola, V.; Wang, T.; Wang, S.; Marsland, A. L.; Kaufman, B. A.; St-Onge, M.-P.; Sloan, R.; Juster, R.-P.; Gouspillou, G.; Hirano, M.; Picard, M.; Trumpff, C.
10.1101/2024.04.19.590241 — physiology — Posted on 2024-11-29
121 Upregulation of DEK Expression in Uterine Myomas and Cervical Cancer as a Potential Prognostic Factor
Janiak, A.; Tan, P.; Kappes, F.; Petraglia, F.; Donati, C.; Liu, X.; Koviazina, R.; Sheng, F.; Tsigkou, A.
10.1101/2024.08.12.607532 — cancer biology — Posted on 2024-11-29
122 Cardiac Reprogramming with Drug Resistance Alleviates Doxorubicin-induced Cardiotoxicity in Mice and Pigs
Zhang, Y.; Li, W.; Xiao, Y.; Luo, L.; Ai, J.; Mo, S.; Li, L.; Deng, J.; Wang, X.; Li, Q.; Zeng, Y.; Liu, H.; Wang, F.; Li, Z.
10.1101/2024.11.28.625834 — bioengineering — Posted on 2024-11-29
123 A Large-Scale Foundation Model for RNA Function and Structure Prediction
Zou, S.; Tao, T.; Mahbub, S.; Ellington, C. N.; Algayres, R. J.; Li, D.; Zhuang, Y.; Wang, H.; Song, L.; Xing, E. P.
10.1101/2024.11.28.625345 — bioinformatics — Posted on 2024-11-29
124 Development of antigen-dextramers for detection and evaluation of CAR T cells
Friis, R.; Ormhoej, M.; Kruger-Jensen, C.; Barden, M.; Ramanathan, K.; Hansen, M.; Abken, H.; Hadrup, S. R.
10.1101/2024.11.27.625576 — bioengineering — Posted on 2024-11-29
125 The Potential of CCA-associated Bacteria to Fight Antimicrobial-Resistant Pathogens: a Genomic Survey
Lera-Lozano, D.; Ruiz-Toquica, J. S.; Holt, M. W.; Jones, E. K.; Ritchie, K. B.; Medina, M.; Gonzalez-Pech, R. A.
10.1101/2024.11.26.625565 — genomics — Posted on 2024-11-29
126 A Portable and Scalable Genomic Analysis Pipeline for Streptococcus pneumoniae Surveillance: GPS Pipeline
Hung, H. C. H.; Kumar, N.; Dyster, V.; Yeats, C.; Metcalf, B.; Li, Y.; Hawkins, P. A.; McGee, L.; Bentley, S. D.; Lo, S. W.
10.1101/2024.11.27.625679 — genomics — Posted on 2024-11-29
131 Unraveling Microglial Spatial Organization in the Developing Human Brain with DeepCellMap, a Deep Learning Approach Coupled to Spatial Statistics
Perochon, T.; Krsnik, Z.; Massimo, M.; Ruchiy, Y.; Romero, A. L.; Mohammadi, E.; Li, X.; Long, K. R.; Parkkinen, L.; Blomgren, K.; Lagache, T.; Menassa, D. A.; holcman, d.
10.1101/2024.11.28.625932 — developmental biology — Posted on 2024-11-29
135 Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
MacLean, A. J.; Deimel, L. P.; Zhou, P.; ElTanbouly, M. A.; Merkenschlager, J.; Ramos, V.; Santos, G. S.; Hagglof, T.; Mayer, C. T.; Hernandez, B.; Gazumyan, A.; Nussenzweig, M. C.
10.1101/2024.11.26.625430 — immunology — Posted on 2024-11-29
136 Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance
Zhang, B.; Orning, P.; Lehman, J. W.; Dinis, A.; Torres-Ulloa, L.; Elling, R.; Kelliher, M. A.; Bertin, J.; Proulx, M. K.; Ryan, L.; Kandasamy, R. K.; Espevik, T.; Pai, A. A.; Fitzgerald, K. A.; Lien, E.
10.1101/2024.11.27.625707 — immunology — Posted on 2024-11-29
137 Mapping essential somatic hypermutations in a CD4-binding site bNAb informs HIV-1 vaccine design
Dam, K.-M. A.; Gristick, H. B.; Li, Y. E.; Yang, Z.; Gnanapragasam, P. N. P.; West, A. P.; Seaman, M. S.; Bjorkman, P. J.
10.1101/2024.11.26.625503 — immunology — Posted on 2024-11-29
141 Reliable amplification of highly repetitive or low complexity sequence DNA enabled by superhelicase-mediated isothermal amplification
Kang, J.; Rashid, F.; Murray, P. J.; Merino-Urteaga, R.; Gavrilov, M.; Shang, T.; Jo, W.; Ahmed, A.; Aksel, T.; Barrick, D.; Berger, J. M.; Ha, T.
10.1101/2024.11.27.625726 — bioengineering — Posted on 2024-11-29
142 An mTurquoise2-based glucose biosensor
Botman, D.; Tielman, A.; Goedhart, J.; Teusink, B.
10.1101/2024.11.29.626064 — biochemistry — Posted on 2024-11-29
146 Enhanced SNP Genotyping with Symmetric Multinomial Logistic Regression
Nielsen, M. B.; Eriksen, P. S.; Mogensen, H. S.; Morling, N.; Andersen, M. M.
10.1101/2024.11.28.625807 — genetics — Posted on 2024-11-29
152 Bridging immunotypes and enterotypes using a systems immunology approach
Affaticati, F.; Ha, M.; Gehrmann, T.; De Boeck, I.; Kuznetsova, M.; Vandoren, R.; Van Deuren, V.; Jansens, H.; De Reu, H.; Schippers, J.; Peeters, K.; Bartholomeus, E.; VanIerssel, S.; Coenen, S.; Naesens, R.; Arien, K.; Vercauteren, K.; Vlieghe, E.; Beutels, P. M. L.; Van Damme, P.; Goossens, H.; Lion, E.; Suls, A.; Lebeer, S.; Laukens, K.; Meysman, P.; Ogunjimi, B.
10.1101/2024.11.29.625344 — systems biology — Posted on 2024-11-29
157 Motor protein-assisted glycan translocation and sequencing using nanopores
Gao, Z.; Ke, W.; Xia, B.; Wu, P.; Ma, S.; Yang, Y.; Zhang, Y.; Zhang, Q.; Lu, X.; Wen, L.; Bai, J.
10.1101/2024.11.27.625763 — bioengineering — Posted on 2024-11-29
161 Mountain roads across the globe significantly alter local soil microclimates
Lejeune, R.; Fuentes-Lillo, E.; Haesen, S.; Piree, A.; Wiegmans, D.; Hostens, L.; Lenoir, J.; Pergl, J.; Vitkova, M.; Seipel, T.; Kutlvasr, J.; Nunez, M. A.; Dimarco, R. D.; Alexander, J.; Ratier Backes, A.; Haider, S.; Pauchard, A.; Nijs, I.; Lembrechts, J. J.
10.1101/2024.11.28.625797 — ecology — Posted on 2024-11-29
163 Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques
Pratap, P. P.; Cottrell, C. A.; Quinn, J.; Carnathan, D. G.; Bader, D. L. V.; Tran, A. S.; Enemuo, C. A.; Ngo, J. T.; Richey, S. T.; Gao, H.; Shen, X.; Greene, K. M.; Hurtado, J.; Ben-Akiva, E.; Michaels, K. K.; Allen, J. D.; Ozorowski, G.; Crispin, M.; Briney, B.; Montefiori, D.; Silvestri, G.; Irvine, D. J.; Crotty, S.; Ward, A. B.
10.1101/2024.11.27.625755 — immunology — Posted on 2024-11-29
165 Spatial Flux Balance Analysis reveals tissue-of-origin and spatially dependent metabolic rewiring in renal and colorectal cancer
Maspero, D.; Marteletto, G.; Lapi, F.; Galuzzi, B. G.; Ruano, I.; Vandenbosch, B.; Yin, K.; Tejpar, S.; Graudenzi, A.; Heyn, H.; Pascual-Reguant, A.; Damiani, C.
10.1101/2024.11.28.625842 — systems biology — Posted on 2024-11-29
168 Structural and functional insights into activation and regulation of the dynein-dynactin-NuMA complex
Aslan, M.; Cho, N. H.; d'Amico, E. A.; Taheri, A.; Zhao, Y.; Zhong, X.; Blaauw, M.; Carter, A. P.; Dumont, S.; Yildiz, A.
10.1101/2024.11.26.625568 — biophysics — Posted on 2024-11-29
174 Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body
Berrevoets, E. S.; Kessler, L. F.; Balakrishnan, A.; Mueller-McNicoll, M.; Rieger, B.; Stallinga, S.; Heilemann, M.
10.1101/2024.11.28.625872 — biophysics — Posted on 2024-11-29
179 Biomimetic porous silicon for rationally engineered combination therapy to induce immunogenic cell death
Saarela, S.; Happonen, E.; Laari, M.-I.; Mohammed, Z.; Saba, S.; Liu, R.; Klefstrom, J.; Lehto, V.-P.; Xu, W.
10.1101/2024.11.28.625849 — bioengineering — Posted on 2024-11-29
181 Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and Atherosclerosis
Knaus, P.; Mendez, P. L.; Raaz, L. V.; Jatzlau, J.; Xiao, Y.; Vrancaert, P.; Ksiazkiewicz, J.; Wallentin, J.; Trumpp, M.; Scharnitzki, S.; Mundlos, S.; Luttun, A.; Zwijsen, A.; Itoh, F.
10.1101/2024.11.25.625323 — genomics — Posted on 2024-11-29
184 Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia
des Amorie, J. R. B.; Betjes, M. A.; Bernink, J.; Hageman, J. H.; Heinz, M. C.; Jordens, I.; Vinck, T.; Houtekamer, R. M.; Verlaan-Klink, I.; Brunner, S. R.; Laskaris, D.; van Rheenen, J.; Gloerich, M.; Clevers, H.; van Zon, J. S.; Tans, S. J.; Snippert, H. J. G.
10.1101/2024.11.28.625899 — cell biology — Posted on 2024-11-29
191 WITHDRAWN: High-fidelity, generalizable light-field reconstruction of biological dynamics with physics-informed meta neural representation
Yi, C.; Ma, Y.; Sun, M.; Yuan, X.; Zhu, L.; Sun, J.; Gao, S.; Zhang, M.; Zhang, Y.; Wang, Z.; Tzung, H.; Li, D.; Liu, b.; Fei, P.
10.1101/2023.11.25.568636 — cell biology — Posted on 2024-11-29
193 Variable inhibition of different Legionella species by antagonistic bacteria
Cavallaro, A.; Probst, S.; Duft, T.; Rieder, M.; Abo El Fateh, O.; Stricker, J.; Gabrielli, M.; Robinson, S. L.; Hammes, F.
10.1101/2024.11.27.625680 — microbiology — Posted on 2024-11-29
195 Adults patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still's disease
Veiga, R.; De Vuyst, L.; Neumann, J.; Bucken, L.; Prezzemolo, T.; Willemsen, M.; Vanderschueren, S.; Matthys, P.; Immunome Project Consortium for Autoinflammatory Disorders (ImmunAID), ; Wouters, C.; Humblet-Baron, S.; Liston, A.
10.1101/2024.11.27.625689 — immunology — Posted on 2024-11-29
197 Using deep learning to predict internalizing problems from brain structure
Vandewouw, M. M.; Syed, B.; Barnett, N.; Arias, A.; Kelley, E.; Jones, J.; Ayub, M.; Iaboni, A.; Arnold, P. D.; Crosbie, J.; Schachar, R. J.; Taylor, M. J.; Lerch, J. P.; Anagnostou, E.; Kushki, A.
10.1101/2024.11.28.625869 — neuroscience — Posted on 2024-11-29
198 Multi-stream predictions in human auditory cortex during natural music listening
Robert, P.; Van Cang, M. P.; Mercier, M.; Trebuchon, A.; Bartolomei, F.; Arnal, L. H.; Morillon, B.; Doelling, K.
10.1101/2024.11.27.625704 — neuroscience — Posted on 2024-11-29
199 Resting-state alpha reactivity is reduced in Parkinson disease and associated with gait variability
Lirani-Silva, E.; Silva, L. C. S.; Orcioli-Silva, D.; Beretta, V. S.; Franca, L. G. S.; Coelho, D. B.; Vitorio, R.
10.1101/2024.11.27.625690 — neuroscience — Posted on 2024-11-29
200 Therapeutic effects of a purified chitin-binding protein from Moringa oleifera seeds on irinotecan-induced intestinal mucositis in mice
Ferreira, K. Q.; Do Carmo, L. D.; Rabelo, L. M. A.; Lopes, T. D. P.; Wong, D. V. T.; Cajado, A. G.; Leitao, R. F. d. C.; Sousa, D. O. B.; Alencar, N. M. N. d.
10.1101/2024.11.27.625542 — pharmacology and toxicology — Posted on 2024-11-29
203 Adherent-suspension plasticity promotes the dissemination and colonization of circulating tumor cells
Huh, H. D.; Sub, Y.; Kim, J. H.; Lee, H.; Oh, J.; Lee, D. K.; Hwa, B. J.; Pyun, W. Y.; Bae, S. J.; Pak, S.; Lee, H.-C.; Choi, J.; Jeong, J.; Gee, H. Y.; Park, H. W.
10.1101/2024.11.25.625320 — cancer biology — Posted on 2024-11-28
204 An annotated biobank of triple negative breast cancer patient-derived xenografts featuring treatment-naive and longitudinal samples throughout neoadjuvant chemotherapy
Rinkenbaugh, A. L.; Qi, Y.; Cai, S.; Shao, J.; Hancock, F.; Jeter-Jones, S.; Zhang, X.; Powell, E.; Huo, L.; Lau, R.; Fu, C.; Gould, R.; den Hollander, P.; Ravenberg, E. E.; White, J. B.; Rauch, G. M.; Arun, B.; Yam, C.; Thompson, A. M.; Echeverria, G. V.; Moulder, S. L.; Symmans, W. F.; Chang, J. T.; Piwnica-Worms, H.
10.1101/2024.11.25.625287 — cancer biology — Posted on 2024-11-28
206 NoButter: An R package for reducing transcript dis-persion in CosMx Spatial Molecular Imaging Data
O'Hora, B.; Laddach, R.; Nuamah, R.; Alberts, E.; Wall, I.; Bell, J.; Johnston, D. A.; James, S.; Norman, J.; Jones, M. G.; Chiappini, C.; Grigoriadis, A.; Quist, J.
10.1101/2024.11.25.625243 — bioinformatics — Posted on 2024-11-28
210 Language Models for Molecular Dynamics
Murtada, M. H.; Brotzakis, Z. F.; Vendruscolo, M.
10.1101/2024.11.25.625337 — bioinformatics — Posted on 2024-11-28
215 Design of high specificity binders for peptide-MHC-I complexes
Liu, B.; Greenwood, N. F.; Bonzanini, J. E.; Motmaen, A.; Sharp, J.; Wang, C.; Visani, G. M.; Vafeados, D. K.; Roullier, N.; Nourmohammad, A.; Garcia, K. C.; Baker, D.
10.1101/2024.11.28.625793 — immunology — Posted on 2024-11-28
217 D-glucuronyl C5-epimerase binds to EGFR to suppress kidney fibrosis
Jing, X.; Wu, J.; Ning, J.; Ding, X.; Du, Z.; Wang, X.; Huang, L.; Wang, R.; Mei, C.; Ding, K.
10.1101/2024.11.25.625114 — pathology — Posted on 2024-11-28
218 Structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography
Gonzalez-Magaldi, M.; Gullapalli, A.; Papoulas, O.; Liu, C.; Leung, A. Y.- H.; Guo, L.; Brilot, A. F.; Marcotte, E. M.; Ke, Z.; Leahy, D. J.
10.1101/2024.11.25.625301 — biophysics — Posted on 2024-11-28
221 Effects of Uni- and Bidirectional Interaction During Dyadic Ankle and Wrist Tracking
Short, M. R.; Ludvig, D.; Di Tommaso, F.; Vianello, L.; Kücüktabak, E. B.; Perreault, E. J.; Lynch, K. M.; Hargrove, L.; Burdet, E.; Pons, J. L.
10.1101/2024.11.25.624926 — bioengineering — Posted on 2024-11-28
226 Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut
Li, C.; Adamson, C.; Ng, A. W. R.; Liang, Y.; Hong, Z.; Loh, J. T.; Ng, S. K.; Kwan, J. M. C.; Feng, S.; Ng, E. W. L.; Kumar, N. S.; Ruedl, C.; Wong, S. H.; Lam, K.-P.; Qiao, Y.
10.1101/2024.11.27.625627 — biochemistry — Posted on 2024-11-28
229 Combining Glycosidases and Nanopore Technology for Glycan Sequencing
Gao, Z.; Yao, G.; Xia, B.; Wei, F.; Wang, J.; Yang, Y.; Ma, S.; Ke, W.; Li, T.; Cheng, X.; Wen, L.; Long, Y.-t.
10.1101/2024.11.28.625867 — biochemistry — Posted on 2024-11-28
234 Temporal and spatial distribution of microbial community in urban river in Dhaka
ALOM, M. M.; Nizhum, A. H.; Mannan, A. B. A.; Sultana, M.; Rahman, S. M.
10.1101/2024.11.26.625349 — genomics — Posted on 2024-11-28
235 Efficient creation and characterization of multi-kilobase knockins by CRISPR/Cas9 and multiple rAAVs
Sentmanat, M. F.; Wang, Z. T.; Kouranova, E.; Peters, S.; Chan, W. C.; Lin, J.; Miao, Y.; Richey, J.; O'Neal, J.; Dipersio, J.; White, M.; Wallace, M.; Cui, X.
10.1101/2024.11.26.625457 — genetics — Posted on 2024-11-28
236 A genome-scale single cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines
Feng, C.; Peets, E.; Zhou, Y.; Crepaldi, L.; Usluer, S.; Dunham, A. S.; Braunger, J. M.; Su, J.; Strauss, M. E.; Muraro, D.; Cheam, A. X.; Bonder, M. J.; Nogales, E. G.; Cooper, S.; Bassett, A. R.; Leonard, S.; Gu, Y.; Fussing, B.; Burke, D.; Parts, L.; Stegle, O.; Velten, B.
10.1101/2024.11.28.625833 — genetics — Posted on 2024-11-28
238 PIEZO1 overexpression in hereditary hemorrhagic telangiectasia arteriovenous malformations
Park, H.; Lee, S.; Furtado, J.; Robinson, M.; Schwartz, M.; Young, L. H.; Eichmann, A.
10.1101/2024.11.27.625696 — molecular biology — Posted on 2024-11-28
239 The piRNA pathway mediates transcriptional silencing of LTR retrotransposons in the soma and germline of Aedes mosquitoes
Taskopru, E.; Bacchi, M.; Overheul, G. J.; Linthout, C.; Koenraadt, C. J. M.; Qu, J.; Miesen, P.; Halbach, R.; van Rij, R. P.
10.1101/2024.11.28.623418 — molecular biology — Posted on 2024-11-28
242 Structural basis for the synergistic assembly of the snRNA export complex
Dubiez, E.; Garland, W.; Brask, M. F.; Erba, E. B.; Jensen, T.; Kadlec, J.; Cusack, S.
10.1101/2024.11.28.625805 — molecular biology — Posted on 2024-11-28
243 The impact of fold-dilution and diluent volume on the estimation of colony forming units in a bacterial culture
Jain, M.; Begum, S.; Bhuyan, S.; Nath, C.; Kashyap, U.; Dutta, L.; Giri, S. J.; Deka, N.; Mandal, M.; Kumar, A.; Ray, S. K.
10.1101/2024.11.28.625891 — microbiology — Posted on 2024-11-28
244 Revealing the diversity of commensal corynebacteria from a single human skin site
Thomas, G. H.; Herman, R.; Meaden, S.; Rudden, M.; Cornmell, R.; Wilkinson, A. J.; Murphy, B.
10.1101/2024.11.28.625817 — microbiology — Posted on 2024-11-28
245 The adaptation of chlamydiae to facultative host multicellularity
Helmlinger, L.; Arthofer, P.; Cyran, N.; Collingro, A.; Horn, M.
10.1101/2024.11.28.625222 — microbiology — Posted on 2024-11-28
246 Natural variation of the drug-binding residues in eukaryotic ribosomes
Chan, L. I.; Ekemezie, C. L.; Brown, C. R.; Helena-Bueno, K.; Williams, T. A.; Melnikov, S. V.
10.1101/2024.11.28.625670 — microbiology — Posted on 2024-11-28
247 Characterization of widely conserved novel pigment production in Bacillus subtilis species
Stannius, R. O.; Dunlap, C. A.; Morvan, E.; Berbon, M.; Lecomte, S.; Loquet, A.; Kovacs, A. T.
10.1101/2024.11.28.625866 — microbiology — Posted on 2024-11-28
248 Discovery of alternative stable states in a synthetic human gut microbial community
Garza, D. R.; Liu, B.; van de Velde, C.; Saha, P.; Zhou, X.; Gonze, D.; Simoens, K.; Bernaerts, K.; Faust, K.
10.1101/2024.11.28.625814 — microbiology — Posted on 2024-11-28
251 A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord.
Soffers, J. H.; Beck, E.; Sytkowski, D.; Maughan, M.; Devasi, D.; Zhu, Y.; Wilson, B.; Erclik, T.; Truman, J.; Skeath, J.; Lacin, H.
10.1101/2024.11.27.625713 — developmental biology — Posted on 2024-11-28
253 A New Role for RNA G-quadruplexes in Aging and Alzheimer's Disease
Kallweit, L.; Saternos, H.; Hamlett, E. D.; Gilmore, A.; Granholm, A.-C.; Horowitz, S.
10.1101/2023.10.02.560545 — neuroscience — Posted on 2024-11-28
255 Arabidopsis thaliana LSM7 is essential for auxin-mediated regulation of SAUR genes and thermomorphogenesis
Nardeli, S. M.; Zacharaki, V.; Rojas-Murcia, N.; Collani, S.; Wang, K.; Bayer, M.; Schmid, M.; Goretti, D.
10.1101/2023.03.28.534379 — plant biology — Posted on 2024-11-28
256 Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition
Zhang, T.; Shin, S.; McCrimmon, C.; Theocharous, M.; Schittenhelm, R. B.; Jarde, T.; Daly, R. J.; Nguyen, L. K.
10.1101/2024.10.27.620536 — cancer biology — Posted on 2024-11-28
260 Megabouts: a flexible pipeline for zebrafish locomotion analysis
Jouary, A.; Silva, P. T. M.; Laborde, A.; Mata, J. M.; Marques, J. C.; Collins, E.; Peterson, R. T.; Machens, C. K.; Orger, M. B.
10.1101/2024.09.14.613078 — animal behavior and cognition — Posted on 2024-11-28
263 Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys
Uche-Dike, R.; Tolman, E. R.; Benischek, C.; Schneider, M.; Kohli, M.; Bush, J.; Frandsen, P. B.; Errigo, I.; Frankel, W.; Gnojewski, K.; Chmura, K.; Jordan, D.; Kittler, H.; Liao, M.; Tobin, T.; Su, C.; Castillo, G.; Derdarian, E.; Wei, M.; Fernandez-Jaurez, S.; Tomano, T.; Gallafent, B.; Jenson, J.; Walser, C. A.; Ware, J. L.; Beatty, C. D.
10.1101/2024.11.26.625270 — ecology — Posted on 2024-11-28
264 SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state
Sebastian-Perez, R.; Nakagawa, S.; Tu, X.; Aranda, S.; Pesaresi, M.; Gomez-Garcia, P. A.; Alcoverro-Bertran, M.; Gomez-Vazquez, J. L.; Carnevali, D.; Borras, E.; Sabido, E.; Martin, L.; Nissim-Rafinia, M.; Meshorer, E.; Neguembor, M. V.; Di Croce, L.; Cosma, M. P.
10.1101/2023.04.15.537018 — developmental biology — Posted on 2024-11-28
265 MLL4 regulates postnatal palate growth and midpalatal suture development
Lee, J.-M.; Jung, H.; de Paula Machado Pasqua, B.; Park, Y.; Tang, Q.; Jeon, S.; Lee, S.-K.; Lee, J. W.; Kwon, H.-J. E.
10.1101/2024.07.16.603832 — developmental biology — Posted on 2024-11-28
266 VPS41 deletion triggers progressive loss of insulin stores and downregulation of beta-cell identity
Yau, B.; An, Y.; Germanos, M.; Schwarzkopf, P.; van der Kraan, G.; Larance, M.; Webster, H.; Burns, C.; Asensio, C.; Kebede, M. A.
10.1101/2024.04.17.589848 — cell biology — Posted on 2024-11-28
267 Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus
Cole, J.; Raguideau, S.; Abbaszadeh-Dahaji, P.; Hilton, S.; Muscatt, G.; Mushinski, R. M.; Nilsson, R. H.; Ryan, M. H.; Quince, C.; Bending, G. D.
10.1101/2024.11.27.625642 — microbiology — Posted on 2024-11-28
268 The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells
Tu, T. H.; Bennani, F. E.; Masroori, N.; Liu, C.; Nemati, A.; Rozza, N.; Grunbaum, A. M.; Kremer, R.; Milhalcioiu, C.; Roy, D.-C.; Rudd, C.
10.1101/2024.11.26.624714 — immunology — Posted on 2024-11-28
269 Widespread Associations between Behavioral Metrics and Brain Microstructure in ASD Suggest Age Mediates Subtypes of ASD
Ressa, H.; Newman, B. T.; Jacokes, Z.; McPartland, J.; Kleinhans, N. M.; Druzgal, T. J.; Pelphrey, K. A.; Van Horn, J. D.; the GENDAAR Research Consortium,
10.1101/2024.09.04.611183 — neuroscience — Posted on 2024-11-28
273 The role of phosphorylation and dephosphorylation in the regulation of Rubisco activase
Bhatnagar, N.; Chung, S. S.; Hodge, J.; Boyd, R.; Kim, S. Y.; Sands, M.; Leakey, A.; Ort, D. R.; Burgess, S. J.
10.1101/2024.08.27.609719 — plant biology — Posted on 2024-11-28
274 Lewy-MSA hybrid fold drives distinct neuronal a-synuclein pathology
Enomoto, M.; Martinez-Valbuena, I.; Forrest, S. L.; Xu, X.; Munhoz, R. P.; Li, J.; Rogaeva, E.; Lang, A. E.; Kovacs, G. G.
10.1101/2024.11.21.624748 — pathology — Posted on 2024-11-28
275 A coarse-grained model of disordered RNA for simulations of biomolecular condensates
Yasuda, I.; von Bülow, S.; Tesei, G.; Yamamoto, E.; Yasuoka, K.; Lindorff-Larsen, K.
10.1101/2024.11.26.625489 — biophysics — Posted on 2024-11-28
276 The invasion pore induced by Toxoplasma gondii
Kegawa, Y.; Male, F.; Jimenez Munguia, I.; Blank, P. S.; Mekhedov, E.; Ward, G.; Zimmerberg, J.
10.1101/2024.10.11.617945 — biophysics — Posted on 2024-11-28
280 Resting-state functional connectivity and fast spindle temporal organization contribute to episodic memory consolidation in healthy aging
Hamel, A.; Champetier, P.; Rehel, S.; Andre, C.; Landeau, B.; Mezenge, F.; Haudry, S.; Roquet, D.; Vivien, D.; de La Sayette, V.; Chetelat, G.; Rauchs, G.; Mary, A.
10.1101/2024.11.28.625682 — neuroscience — Posted on 2024-11-28
281 st-DenseViT: A Weakly Supervised Spatiotemporal Vision Transformer for Dense Prediction of Dynamic Brain Networks
Kazemivash, B.; suresh, p. n.; Ye, D. H.; Iraji, A.; Liu, J.; Plis, S.; kochunov, p.; Calhoun, V.
10.1101/2024.11.28.625914 — neuroscience — Posted on 2024-11-28
285 Hippocampal CA2 neurons disproportionately express AAV-delivered genetic cargo
Alexander, G.; He, B.; Leikvoll, A.; Jones, S.; Wine, R.; Kara, P.; Martin, N. P.; Dudek, S. M.
10.1101/2024.11.27.625768 — neuroscience — Posted on 2024-11-28
286 More or less latent variables in the high-dimensional data space? That is the question
Vaccari, F. E.; Diomedi, S.; Bettazzi, E.; Filippini, M.; De Vitis, M.; Hadjidimitrakis, K.; Fattori, P.
10.1101/2024.11.28.625854 — neuroscience — Posted on 2024-11-28
290 Awareness of the future: Dolphins know when they need to remember for the future
Ortiz, S. T.; Smeele, S. Q.; Osvath, M.; Guerrero, A. M.; Sanchez, A. H.; Ramirez, C. U.; Almunia, J.; von Bayern, A. M. P.
10.1101/2024.11.28.625857 — animal behavior and cognition — Posted on 2024-11-28
294 Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition.
Krishnan, S.; Lima, A.; Low, Y. T.; Montero, S. P.; Tan, S.; Gregorio, A. D.; Barreto, A. P.; Bowling, S.; Vousden, K.; Rodriguez, T. A.
10.1101/2024.11.28.625863 — developmental biology — Posted on 2024-11-28
295 Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida
He, M.; Tao, Y.; Mu, K.; Feng, H.; Fan, Y.; Liu, T.; Huang, Q.; Xiao, Y.; Chen, W.
10.1101/2024.07.28.605504 — microbiology — Posted on 2024-11-28
296 Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency
Millard, S. K.; Chiang, A. K.; Humburg, P.; Chowdhury, N.; Rehan, R.; Furman, A. J.; Mazaheri, A.; Schabrun, S. M.; Seminowicz, D. A.
10.1101/2023.08.11.552723 — neuroscience — Posted on 2024-11-28
299 Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signalling in Drosophila
Vincze, V.; Esküdt, Z.; Feher-Juhasz, E.; Chhatre, A. S.; Jipa, A.; Csordos, M.; Galambos, A. R.; Feil-Börcsök, D.; Juhasz, G.; Szabo, A.
10.1101/2024.08.28.610109 — neuroscience — Posted on 2024-11-28
300 High-resolution imaging atlas reveals context-dependent role of pancreatic sympathetic innervation in diabetic mice
Xu, Q.; Chen, Y.; Ni, X.; Zhuang, H.; Cao, S.; Zhao, L.; Wang, L.; Chen, J.; Yang, W.; Zeng, W.; Li, X.; Sun, H.; Shen, W.
10.1101/2024.11.14.623708 — neuroscience — Posted on 2024-11-28
301 The role of cholinergic signaling in multi-sensory gamma stimulation induced perivascular clearance of amyloid
Lavoie, N. S.; Blanco-Duque, C.; Kahn, M.; Nawaid, H.; Loon, A.; Seguin, A.; Raju, R.; Davison, A.; Yang, C.-Y.; Tsai, L.-H.
10.1101/2024.11.27.625739 — neuroscience — Posted on 2024-11-28
302 Synergistic Behavioral and Neuroplastic Effects of Psilocybin-NMDAR Modulator Administration.
Ben Tal, T.; Pogodin, I.; Botvinnik, A.; Lifschytz, T.; Heresco-Levy, U.; Lerer, B.
10.1101/2024.11.28.625811 — neuroscience — Posted on 2024-11-28
304 Gustatory sensitivity to amino acids in bumblebees
Rossoni, S.; Parkinson, R. H.; Niven, J. E.; Nicholls, E.
10.1101/2024.11.28.625904 — neuroscience — Posted on 2024-11-28
306 Hunger alters approach-avoidance behaviours differently in male and female mice
Anversa, R. G.; Goldstein, G.; Syed, I.; Dempsey, H.; Pearl, A.; Maddern, X. J.; Brown, R. M.; Reed, F. M.; Lawrence, A. J.; Walker, L. C.
10.1101/2024.11.27.625796 — neuroscience — Posted on 2024-11-28
309 H2-driven xylitol production in Cupriavidus necator H16
Jämsä, T.; Claassens, N. J.; Salusjärvi, L.; Nyyssölä, A.
10.1101/2024.10.22.619622 — bioengineering — Posted on 2024-11-28
311 Ultra-High Dose Rate Helium Ion Beams: Minimizing Brain Tissue Damage while Preserving Tumor Control
Dokic, I.; Moustafa, M.; Tessonnier, T.; Meister, S.; Ciamarone, F.; Akbarpour, M.; Krunic, D.; Haberer, T.; Debus, J.; Mairani, A.; Abdollahi, A.
10.1101/2024.06.13.598785 — cell biology — Posted on 2024-11-28
314 Population-based metaproteomics reveals functional associations between gut microbiota and phenotypes
Liang, S.; Sun, Y.; Miao, Z.; Li, B.-y.; Xing, Z.; Xie, Y.; Cai, E.; Li, S.; Liu, P.; Yang, M.; Shuai, M.; Gou, W.; Jiang, W.; Wang, Y.; Gao, H.; Zhang, K.; Yu, J.; Cai, X.; Wang, X.; Chen, Y.-m.; Zheng, J.-S.; Guo, T.
10.1101/2024.11.26.625569 — microbiology — Posted on 2024-11-28
317 Different Roles of D1/D2 Medium Spiny Neurons in the Nucleus Accumbens in Pair Bond Formation of Male Mandarin Voles
Zhang, L.; Qu, Y.; Young, L. J.; Hou, W.; Liu, L.; Liu, J.; Wang, Y.; Li, L.; Guo, X.; Li, Y.; Huang, C.; Lv, Z.; Li, Y.-T.; Jia, R.; Lian, T.; Feng, H.; He, Z.; Tai, F.-D.
10.1101/2024.07.24.604911 — neuroscience — Posted on 2024-11-28
318 Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping
Tucciarelli, R.; Bird, L.; Straka, Z.; Szymanska, M.; Kollamkulam, M.; Sonar, H.; Paik, J.; Clode, D.; Hoffmann, M.; Cowie, D.; Makin, T. R.
10.1101/2024.11.26.624817 — neuroscience — Posted on 2024-11-28
322 Drone-Based Identification of Flood-Tolerant Maize via Multispectral Imaging: A Real-World Case Study
Mitchell, M. N.; Sidberry, G.; Mathison, M.; DeSalvio, A. J.; Kick, D. R.; Washburn, J. D.
10.1101/2024.11.26.625493 — plant biology — Posted on 2024-11-28
323 Rhamnogalacturonan-II dimerization deficiency impairs the coordination between growth and adhesion maintenance in plants
Baba, A. I.; Lisica, L.; Atakhani, A.; Aryral, B.; Bogdziewiez, L.; Erguvan, O.; Heymans, A.; Jewaria, P. K.; Smith, R. S.; Bhalerao, R. P.; Verger, S.
10.1101/2024.11.26.625362 — plant biology — Posted on 2024-11-28
324 Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System
Imam, F. T.; Gillespie, T. H.; Ziogas, I.; Surles-Zeigler, M. C.; Tappan, S.; Ozyurt, B.; Boline, J.; de Bono, B.; Grethe, J. S.; Martone, M. E.
10.1101/2024.10.25.620360 — bioinformatics — Posted on 2024-11-28
326 Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins
Xu, D.; Besselink, S.; Ramadoss, G. N.; Dierks, P. H.; Lubin, J. P.; Pattali, R. K.; Brim, J. I.; Christenson, A. E.; Colias, P. J.; Ornelas, I. J.; Nguyen, C. D.; Chasins, S. E.; Conklin, B. R.; Nunez, J. K.
10.1101/2024.11.26.625496 — genetics — Posted on 2024-11-28
329 pnetr: An R package for the PnET family of forest ecosystem models
Gao, X.; Zhou, Z.; Ollinger, S. V.; Matthes, J. H.; Jiao, W.; Thompson, J.
10.1101/2024.11.26.625449 — ecology — Posted on 2024-11-28
330 The effects of early-life ambient temperature on the gut microbiome of a wild bird? an experimental approach
Ruuskanen, S.; Hollmen, L.; Stier, A.; Hsu, B.-Y.; Cossin-Sevrin, N.; Marciau, C.; Hukkanen, M.; Vesterinen, E.
10.1101/2024.11.26.625491 — ecology — Posted on 2024-11-28
331 Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys
Uche-Dike, R.; Tolman, E. R.; Benischek, C.; Schneider, M.; Kohli, M.; Bush, J.; Frandsen, P. B.; Errigo, I.; Frankel, W.; Gnojewski, K.; Chmura, K.; Jordan, D.; Kittler, H.; Liao, M.; Tobin, T.; Su, C.; Castillo, G.; Derdarian, E.; Wei, M.; Fernandez-Jaurez, S.; Tomano, T.; Gallafent, B.; Jenson, J.; Walser, C. A.; Ware, J. L.; Beatty, C. D.
10.1101/2024.11.26.625270 — ecology — Posted on 2024-11-28
333 Lamin B1-dependent regulation of human separase in mitosis
Picotto, J.; Cipressa, F.; Busso, D.; Cenci, G.; Bertrand, P.; Pennarun, G.
10.1101/2024.11.28.625860 — cell biology — Posted on 2024-11-28
334 The inflammasome sensor NLRP3 interacts with REV7 to maintain genome integrity through homologous recombination
Burlet, D.; Khan, M. M.; Hacot, S.; Buthmann, H.; Bardoulet, L.; Huber, A.-L.; Gorry, J.; Lopez, B. S.; Coute, Y.; Geyer, M.; Tissier, A.; PETRILLI, V.
10.1101/2024.11.28.625806 — molecular biology — Posted on 2024-11-28
335 Whole-Brain Causal Discovery Using fMRI
Arab, F.; Ghassami, A.; Jamalabadai, H.; Peters, M. A. K.; Nozari, E.
10.1101/2023.08.12.553067 — neuroscience — Posted on 2024-11-28
338 An Omics approach on Marchantia polymorpha single FERONIA and MARIS homologs confirms links between cell wall integrity and abscisic acid
Jobe, T. O.; Gaspar Litholdo, C.; Stolze, S. C.; Stephan, L.; Westermann, J.; Harzen, A.; Hulskamp, M.; Nakagami, H.; Boisson-Dernier, A.
10.1101/2024.11.26.625412 — plant biology — Posted on 2024-11-28
344 SMAC mimetics induce human macrophages to phagocytose live cancer cells
Liu, S. Y.; Hulsman, M.; Leyendecker, P.; Chang, E.; Donovan, K. A.; Strobel, F.; Dougan, J.; Fischer, E. S.; Dougan, M.; Dougan, S. K.; Qiang, L.
10.1101/2024.11.25.625306 — immunology — Posted on 2024-11-28
345 Covert muscle activity reveals dynamic freezing states and prepares the animal for action
Hobbiss, A. F.; Franco, M. C.; Medeiros, A. M.; Rosher, C.; Mendes, C. S.; Moita, M. A.
10.1101/2024.11.26.622641 — neuroscience — Posted on 2024-11-28
347 Quantitative genetics of photosynthetic trait variation in maize
Ali, W.; Grzybowski, M.; Torres-Rodriguez, J. V.; Li, F.; Shrestha, N.; Mathivanan, R. K.; de Bernardeaux, G.; Hoang, K.; Mural, R.; Roston, R.; Schnable, J.; Sahay, S.
10.1101/2024.11.25.625283 — plant biology — Posted on 2024-11-28
349 Sexual dimorphism of MASLD-driven bone loss
Goldscheitter, G. M.; Seneshaw, M.; Mirshahi, F.; Buettmann, E.; Genetos, D.; Sanyal, A.; Donahue, H.
10.1101/2024.11.25.625246 — physiology — Posted on 2024-11-28
350 Oncogenic GNAQ/11-induced remodeling of the IP3/Calcium signaling pathway protects Uveal Melanoma against Calcium-driven cell death
Garcia, C.; Roussel, L.; Massaad, S.; Brard, L.; La Rovere, R.; Tartare-Deckert, S.; Bertolotto, C.; Bultynck, G.; Leverrier-Penna, S.; Penna, a.
10.1101/2024.11.25.625282 — cancer biology — Posted on 2024-11-28
351 Molecular characterization of the archaic HLA-B*73:01 allele reveals presentation of a unique peptidome and skewed engagement by KIR2DL2
Ross, P.; Hilton, H. G.; Lodwick, J.; Slezak, T.; Guethlein, L. A.; McMurtrey, C. P.; Han, A. S.; Nielsen, M.; Yong, D.; Dulberger, C. L.; Nolan, K. T.; Roy, S.; Castro, C. D.; Hildebrand, W. H.; Zhao, M.; Kossiakoff, A.; Parham, P.; Adams, E. J.
10.1101/2024.11.25.625330 — biochemistry — Posted on 2024-11-28
352 Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability
Dürauer, S.; Kang, H.-S.; Wiebeler, C.; Machida, Y.; Schnapka, D. S.; Yaneva, D.; Renz, C.; Götz, M. J.; Weickert, P.; Major, A. C.; Rahmanto, A. S.; Guthenthaler-Tietze, S. M.; Daumann, L. J.; Beli, P.; Ulrich, H. D.; Sattler, M.; Machida, Y. J.; Schwierz, N.; Stingele, J.
10.1101/2024.11.26.625192 — biochemistry — Posted on 2024-11-28
354 Prochlorococcus predation by a globally abundant filter feeder
Sweeney, C.; Harman, A.; Kerkar, A. U.; Aasjord, A. E.; Chouroutt, D. M.; Hiebert, T.; Sutherland, k.; Thompson, A. W.
10.1101/2024.11.25.625256 — ecology — Posted on 2024-11-28
356 HelD is a Global Transcription Factor Enhancing Gene Expression in Rapidly Growing Mycobacteria
Vankova, V.; Kumar, D.; Shoman, M.; Schwarz, M.; Modrak, M.; Jirat Matejckova, J.; Neva, S.; Havelkova, J.; Sikova, M.; Pospsiilova, D.; Halada, P.; Sanderova, H.; Holubova, J.; Dohal, M.; Prevorovsky, M.; Stanek, O.; Knejzlik, Z.; Dvorakova, V.; Hnilicova, J.
10.1101/2024.11.27.625628 — microbiology — Posted on 2024-11-28
357 The activation of ATR during unperturbed DNA replication is restricted by VCP/p97 through the extraction of DNA polymerase α/Primase from chromatin
Rodriguez-Acebes, S.; Martin-Rufo, R.; Gomez-Moya, A.; Churcher, S. B.; Fernandez-Llorente, A.; de la Vega-Barranco, G.; Perona, A.; Oroz, P.; Martin-Doncel, E.; Toledo, L.; Mendez, J.; Lecona, E.
10.1101/2022.07.25.501345 — molecular biology — Posted on 2024-11-28
359 Unsilenced inhibitory cortical ensemble gates remote memory retrieval
Wang, S.; Sheng, T.; Su, F.; Yang, H.; Cao, R.; Wang, Q.; Fang, W.; Zhang, C.; Lu, W.
10.1101/2024.07.01.601454 — neuroscience — Posted on 2024-11-28
361 Compositional Flexibility of the ER-Mitochondria Encounter Structure
Covill-Cooke, C.; Hirashima, T.; Kawano, S.; Ganellin, J.; Moody, A.; van Schie, S. N. S.; John Peter, A. T.; Saito, C.; Endo, T.; Kornmann, B.
10.1101/2024.11.26.625358 — cell biology — Posted on 2024-11-28
362 Notch Signaling Drives Pro-Regenerative and Migratory Traits in Glandular Stem/Progenitor Cells
Cinat, D.; Maturi, R.; Gunawan, J. P.; Jellema-de Bruin, A. L.; Kracht, L.; Martinez, P. S.; Wu, Y.; Soto-Gamez, A.; van Goethem, M.-J.; Holtman, I. R.; Pringle, S.; Barazzuol, L.; Coppes, R. P.
10.1101/2024.11.27.625738 — cell biology — Posted on 2024-11-28
363 CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication
Yadav, A. K.; Abdirov, A.; Ondruskova, K.; Negi, S.; Kolarova, K.; Dibus, N.; Krejci, J.; Polasek-Sedlackova, H.; Cermak, L.
10.1101/2024.11.26.625391 — cell biology — Posted on 2024-11-28
365 Immortalized Intestinal Telocytes - A Stem Cell Niche In Vitro
Canella, M.; Gharbi, A.; Duran, D.; Ben-Neriah, Y.; Birimberg-Schwartz, L.; Ben-Porath, I.; Grunewald, M.; Shoshkes Carmel, M.
10.1101/2024.11.27.625598 — cell biology — Posted on 2024-11-28
366 Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9
Lyu, W.; Wang, H.; Du, Z.; Wei, R.; He, J.; Meng, F.; Bi, J.; Zhang, L.; Zhang, C.; Guan, Y.; Tao, W.
10.1101/2024.11.27.625711 — cell biology — Posted on 2024-11-28
369 Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain
Gao, Y.; Tillu, V.; Wu, Y.; Rae, J.; Hall, T. E.; Chen, K.-E.; Weeratunga, S.; Guo, Q.; Livingstone, E.; Tham, W.-H.; Parton, R. G.; Collins, B. M.
10.1101/2024.11.26.625551 — cell biology — Posted on 2024-11-28
370 Genomic characterization and functional insights of multidrug-resistant Klebsiella pneumoniae strain BCSIR-JUMIID
Ahmed, M. F.; Faruk, M. O.; Sarkar, M. M. H.; Hossain, M. I.; Shabuj, A. A.-M.; Bhim, M.; Mehzabin, K.; Chowdhury, S. F.; Naser, S. R.; Mumtaz, T.
10.1101/2024.11.27.625610 — microbiology — Posted on 2024-11-28
374 Himalayan whole-genome sequences provide insight into population formation and adaptation
Arciero, E.; Almarri, M. A.; Mezzavilla, M.; Xue, Y.; Hallast, P.; Hammoud, C.; Chen, Y.; Skov, L.; Kraaijenbrink, T.; Ayub, Q.; Yang, H.; van Driem, G.; Jobling, M. A.; de Knijff, P.; Tyler-Smith, C.; Asan, ; Haber, M.
10.1101/2024.11.26.625458 — genomics — Posted on 2024-11-28
376 A non-muscle α-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling
Hayes, J. B.; Ritter, D.; Neininger-Castro, A. C.; Willet, A. H.; Caplan, L. R.; Wang, Y.; Liu, X.; Taneja, N.; Sanchez, Z. C.; Smart, K.; Reinhart-King, C. A.; Liu, Q.; Tyska, M. J.; Tabdanov, E. D.; Wells, Q. S.; Knapik, E. W.; Burnette, D. T.
10.1101/2024.11.26.625523 — cell biology — Posted on 2024-11-28
378 Unveiling the native architecture of adult cardiac tissue using the 3D-NaissI method
PATALUCH, N.; GUILBEAU-FRUGIER, C.; PONS, V.; WAHART, A.; KARSENTY, c.; SENARD, j.-m.; Gales, C.
10.1101/2024.11.26.625417 — cell biology — Posted on 2024-11-28
379 Repeated cigarette smoke exposure attenuates the proliferation rate of primary human lung fibroblasts in vitro
Cannard, E. C.; Kronseder, A.; Karrasch, S.; Kahnert, K.; Nowak, D.; Lehmann, M.; Holz, O.; Stoleriu, M. G.; Jorres, R. A.
10.1101/2024.11.27.625673 — cell biology — Posted on 2024-11-28
380 Cervicovaginal microbial features predicts Chlamydia trachomatis spread to the upper genital tract of infected women
Jeong, S.; Tollison, T. S.; Brochu, H.; Huntress, I.; Yount, K. S.; Zheng, X.; Darville, T.; O'Connell, C. M.; Peng, X.
10.1101/2024.11.26.625070 — microbiology — Posted on 2024-11-28
381 Global evolutionary patterns of Yersinia pestis and its spread into Africa
Mas Fiol, G.; Lemoine, F.; Mornico, D.; Bouvier, G.; Andrades Valtuena, A.; Duchene, S.; Campagne, P.; Baliere, C.; Kwasiborski, A.; Caro, V.; Beau, R.; Savin, C.; Cespedes, M.; Rajerison, M.; Shako, J.-C.; Carniel, E.; Slavin, P.; Rascovan, N.; Pizarro-Cerda, J.
10.1101/2024.11.26.625443 — microbiology — Posted on 2024-11-28
382 The effect of prolonged elbow pain and rTMS on cortical inhibition: A TMS-EEG study
Chowdhury, N.; Chang, W.-J.; Cheng, D.; Manivasagan, N.; Seminowicz, D. A.; Schabrun, S.
10.1101/2024.11.26.625334 — neuroscience — Posted on 2024-11-28
383 Bio-Accelerated Weathering of Ultramafic Minerals with Gluconobacter oxydans
Lee, J. J.; Plante, L.; Pian, B.; Marecos, S.; Medin, S. A.; Klug, J. D.; Reid, M. C.; Gadikota, G.; Gazel, E.; Barstow, B.
10.1101/2024.11.25.625253 — bioengineering — Posted on 2024-11-28
384 Association analyses reveal both anthropic and environmental selective events during eggplant domestication
Omondi, E.; Barchi, L.; Gaccione, L.; Portis, E.; Toppino, L.; Tassone, M. R.; Alonso, D.; Prohens, J.; Rotino, G. L.; Schafleitner, R.; van Zonneveld, M.; Giuliano, G.
10.1101/2024.11.25.625206 — genomics — Posted on 2024-11-28
385 Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti
Bergman, A.; Crist, A. B.; Lopez-Maestre, H.; Blanc, H.; Castello-Sanjuan, M.; Frangeul, L.; Varet, H.; Daron, J.; Merkling, S. H.; Saleh, M. C.; Lambrechts, L.
10.1101/2024.11.26.625377 — genomics — Posted on 2024-11-28
386 An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology
Sokolowski, D. J.; Miclaus, M.; Nater, A.; Faykoo-Martinez, M.; Hoekzema, K.; Zuzarte, P.; Monis, S.; Alvi, S. A.; Erdmann, J.; Erdmann, A. L.; Kumaragurubaran, R.; Bayerl, J.; Yoo, D.; Karimpour, N.; Ungerleider, K.; Hou, H.; Fergal, M.; Hourlier, T.; Clarke, Z. A.; Lischer, H. E.; Leordean, D. V.; Jiang, Y.; Pugh, T. J.; Smith, E. S. J.; Haggerty, L.; Laird, D. J.; Lilue, J.; Holmes, M. M.; Eichler, E. E.; Bruggmann, R.; Simpson, J. T.; Balmus, G.; Wilson, M. D.
10.1101/2024.11.26.625329 — genomics — Posted on 2024-11-28
394 Genome-wide association study of frost tolerance in Vicia faba reveals syntenic loci in cool-season legumes and highlights relevant candidate genes
Imbert, B.; Kreplak, J.; Lejeune-Henaut, I.; Magnin-Robert, J.-B.; Boutet, G.; Marget, P.; AUBERT, G.; Burstin, J.; Tayeh, N.
10.1101/2024.11.27.624268 — plant biology — Posted on 2024-11-28
395 Piezo2 in sensory neurons influences systemic and adipose tissue metabolism
Passini, F. S.; Bornstein, B.; Rubin, S.; Kuperman, Y.; Krief, S.; Masschelein, E.; Mehlman, T.; Brandis, A.; Addadi, Y.; Huri-Ohev Shalom, S.; Richter, E. A.; Yardeni, T.; Tirosh, A.; De Bock, K.; Zelzer, E.
10.1101/2024.11.27.624676 — physiology — Posted on 2024-11-28
399 TCF3::HLF Orchestrates an Enhancer-Promoter Network with Activation of MEF2C to Promote Immature HSC gene Expression in Leukemia
Priebe, V.; Drakul, A.; Galvan, B.; Aguade-Gorgorio, J.; Mikkola, H. K. A.; Bornhauser, B.; Santoro, R.; Bourquin, J.-P.
10.1101/2024.11.26.625006 — cancer biology — Posted on 2024-11-28
401 Aggregating gut: on the link between neurodegeneration and bacterial functional amyloids
Wojciechowska, A. W.; Wojciechowski, J. W.; Zielinska, K.; Soeding, J.; Kosciolek, T.; Kotulska, M.
10.1101/2024.11.26.624671 — bioinformatics — Posted on 2024-11-28
402 Stage-specific CAR-mediated signaling generates naive-like, TCR-null CAR T cells from induced pluripotent stem cells
Yoo, S. P.; Yuan, X.; Engstrom, C.; Chang, P. C.; Li, S.; Lathrop, L. E.; Lagosh, J. A.; Seet, C. S.; Kohn, D. B.; Crooks, G. M.
10.1101/2024.11.25.624041 — bioengineering — Posted on 2024-11-28
405 Cooperative Role of PACT and ADAR1 in Preventing Aberrant PKR Activation by Self-Derived Double-Stranded RNA
Manjunath, L.; Santiago, G.; Ortega, P.; Sanchez, A.; Oh, S.; Garcia, A.; Bournique, E.; Bouin, A.; Semler, B.; Setiaputra, D.; Buisson, R.
10.1101/2024.11.27.625712 — microbiology — Posted on 2024-11-27
406 A generative artificial intelligence approach for antibiotic optimization
Torres, M. D. T.; Zeng, Y.; Wan, F.; Maus, N.; Gardner, J.; de la Fuente-Nunez, C.
10.1101/2024.11.27.625757 — microbiology — Posted on 2024-11-27
408 Distinguishing the activity of adjacent somatosensory nuclei within the brainstem using 3T fMRI
Howell, P.; Odermatt, I.; Harrison, O.; Rabe, F.; Meissner, S.; Freund, P.; Wenderoth, N.; Kikkert, S.
10.1101/2024.11.27.625699 — neuroscience — Posted on 2024-11-27
412 Heterotypic droplet formation by pro-inflammatory S100A9 and neurodegenerative disease-related alpha-synuclein
Veiveris, D.; Kopustas, A.; Sulskis, D.; Mikalauskaite, K.; Tutkus, M.; Smirnovas, V.; Ziaunys, M.
10.1101/2024.11.27.625672 — biochemistry — Posted on 2024-11-27
414 Paired CRISPR screens to map gene regulation in cis and trans
Xue, X.; Gajic, Z. Z.; Caragine, C. M.; Legut, M.; Walker, C.; Kim, J. Y. S.; Wang, X.; Yan, R. E.; Wessels, H.-H.; Lu, C.; Bapodra, N.; Gürsoy, G.; Sanjana, N. E.
10.1101/2024.11.27.625752 — genomics — Posted on 2024-11-27
415 Enhanced in vivo gene knockout with undetectable off-targets using multiplexed Cas12a sgRNAs
Port, F.; Buhmann, M. A.; Zhou, J.; Stricker, M.; Vaughan-Brown, A.; Michalsen, A.-C.; Rossmanith, E.; Poeltl, A.; Grosskurth, L.; Huber, J.; Menendez Kury, L. B.; Weberbauer, B.; Huebl, M.; Heigwer, F.; Boutros, M.
10.1101/2024.11.26.625385 — genetics — Posted on 2024-11-27
416 Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins
Nunez, J. K.; Xu, D.; Besselink, S.; Ramadoss, G. N.; Dierks, P. H.; Lubin, J. P.; Pattali, R. K.; Brim, J. I.; Christenson, A. E.; Colias, P. J.; Ornelas, I. J.; Nguyen, C. D.; Chasins, S. E.; Conklin, B. R.
10.1101/2024.11.26.625496 — genetics — Posted on 2024-11-27
417 Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDS
Prummel, K. D.; Woods, K.; Kholmatov, M.; Schmitt, E.; Vlachou, E. P.; Poschmann, G.; Stuhler, K.; Wehner, R.; Schmitz, M.; Winter, S.; Oelschlaegel, U.; Schwartz, L. S.; Moura, P. L.; Hellstrom-Lindberg, E.; Theobald, M.; Trowbridge, J. J.; Platzbecker, U.; Zaugg, J. B.; Guezguez, B.
10.1101/2024.11.27.625734 — molecular biology — Posted on 2024-11-27
418 A 2022 avian H5N1 influenza A virus from clade 2.3.4.4b attaches to and replicates better in human respiratory epithelium than a 2005 H5N1 virus from clade 2.3.2.1
Bauer, L.; Leijten, L. M.; Iervolino, M.; Copra, V.; van Dijk, L.; Power, m.; Spronken, M.; Rijnink, W.; Funk, M.; de Vries, R. D.; Richard, M.; Kuiken, T.; van Riel, D.
10.1101/2024.11.27.625596 — microbiology — Posted on 2024-11-27
419 A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system
Reglinski, M.; Hurst, Q.; Williams, D.; Gierlinski, M.; Sahin, A. T.; Mathers, K.; Ostrowski, A.; Bergkessel, M.; Zachariae, U.; Pitt, S.; Coulthurst, S.
10.1101/2024.11.27.625605 — microbiology — Posted on 2024-11-27
422 Metabolic Adaptability and Nutrient Scavenging in Toxoplasma gondii: Insights from Ingestion Pathway-Deficient Mutants
Rimple, P. A.; Olafsson, E. B.; Markus, B. M.; Wang, F.; Augusto, L.; Lourido, S.; Carruthers, V. B.
10.1101/2024.11.27.625683 — microbiology — Posted on 2024-11-27
424 Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae: Risk factors and resistance mechanism of ceftazidime/avibactam in China
Wang, N.; Zhan, M.; Deng, L.; Li, H.; Peng, X.; Chang, J.; Hao, J.; Jia, N.; Li, B.; Lei, C.; Wang, T.; Liu, S.; Li, C.; Wang, B.; Zhang, W.
10.1101/2024.11.27.625653 — microbiology — Posted on 2024-11-27
425 Unexplored Yeast diversity in Seed Microbiota
Marchi, M.; Bosc-Bierne, A.; Lerenard, T.; Le Corff, J.; Aligon, S.; Rolland, A.; Simonin, M.; Marais, C.; Briand, M.; Cordovez, V.; Gouka, L.; Guillemette, T.; Simoneau, P.; Guschinskaya, N.
10.1101/2024.11.27.625647 — microbiology — Posted on 2024-11-27
426 Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus
Cole, J.; Raguideau, S.; Abbaszadeh-Dahaji, P.; Hilton, S.; Muscatt, G.; Mushinski, R. M.; Nilsson, R. H.; Ryan, M. H.; Quince, C.; Bending, G. D.
10.1101/2024.11.27.625642 — microbiology — Posted on 2024-11-27
427 Identification and genomic characterization of a novel bisegmented coronavirus in the lesser panda
chen, x.; Guo, H.; Zhou, N.; Shi, Z.; Cui, X.; Dong, T.; Qin, M.; Liang, X.; Shan, F.; Wang, H.; Zuo, Q.; Peng, S.; You, W.; Irwin, D. M.; Chen, W.; Zeng, L.; Ding, C.; Shen, Y.
10.1101/2024.11.26.625429 — microbiology — Posted on 2024-11-27
429 Ciliopathy interacts with neonatal anesthesia to cause non-apoptotic caspase-mediated motor deficits
Saric, N.; Atak, Z.; Sade, C. F.; Reddy, N.; Bell, G.; Tolete, C.; Rajtboriraks, M. T.; Hashimoto-Torii, K.; Jevtovic-Todorovic, V.; Haydar, T. F.; Ishibashi, N.
10.1101/2024.11.27.624302 — neuroscience — Posted on 2024-11-27
430 Pubertal hormones and the early adolescent female brain: a multimodality brain MRI study
Khetan, M.; Vijayakumar, N.; Tian, Y. E.; Herting, M. M.; O'Connell, M.; Seal, M.; Whittle, S.
10.1101/2024.11.27.625122 — neuroscience — Posted on 2024-11-27
431 Visuo-Vestibular Integration for Self-Motion: Human Cortical Area V6 Prefers Forward and Congruent Stimuli
Marchand, S.; Balcou, M.; Picher, P.; Rosito, M.; Mateo, D.; Vayssiere, N.; Durand, J.-B.; Severac Cauquil, A.
10.1101/2024.11.27.625640 — neuroscience — Posted on 2024-11-27
436 Successful establishment of an exogenous gene expression system in Chlamydomnas chloroplast based on viral replication elements
Jiang, Y.; Zhang, G.; Wang, S.; Raza, A.; Liu, X.; Guo, C.; Wu, S.; Luo, J.; Lie, Y.; Liu, Y.; Jia, B.; Hu, Z.-L.
10.1101/2024.11.26.625556 — synthetic biology — Posted on 2024-11-27
437 Rewiring Escherichia coli to Transform Formate into Methyl Groups
Mohr, M. K. F.; Satanowski, A.; Lindner, S.; Erb, T. J.; Andexer, J. N.
10.1101/2024.11.27.625645 — biochemistry — Posted on 2024-11-27
440 In vivo regulation of an endogenously-tagged protein by a light-regulated kinase
vigano, a. m.; Bao, M.; Lepeta, K. J.; Aguilar, G.; Schnider, S. T.; Affolter, M.
10.1101/2024.11.27.625702 — developmental biology — Posted on 2024-11-27
441 A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord.
Soffers, J. H.; Beck, E.; Sytowski, D.; Maughan, M.; Devasi, D.; Zhu, Y.; Wilson, B.; Erclik, T.; Truman, J.; Skeath, J.
10.1101/2024.11.27.625713 — developmental biology — Posted on 2024-11-27
445 The identification of a SARs-CoV2 S1 protein derived peptide with super-antigen-like stimulatory properties on T-cells
Tu, T. H.; Bennani, F. E.; Masroori, N.; Liu, C.; Nemati, A.; Rozza, N.; Grunbaum, A. M.; Kremer, R.; Milhalcioiu, C.; Roy, D.-C.; Rudd, C.
10.1101/2024.11.26.624714 — immunology — Posted on 2024-11-27
446 Insulin resistance, cognition, and functional brain network topology in older adults with obesity
McIntyre, C. C.; Lyday, R. G.; Su, Y.; Nicklas, B. J.; Simpson, S. L.; Deep, G.; Macauley, S. L.; Hugenschmidt, C. E.
10.1101/2024.11.26.625552 — neuroscience — Posted on 2024-11-27
448 A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics
Budinger, D.; Alhaque, S.; Gonzalez-Mendez, R.; Dadswell, C.; Barwick, K.; Ferrini, A.; Roth, C.; McCann, C. J.; Tuschl, K.; Al Jasmi, F.; Zaki, M. S.; Park, J. H.; Dale, R. C.; Mohammad, S.; Christodoulou, J. H.; Moulding, D.; Duchen, M.; Barral, S.; Kurian, M. A.
10.1101/2024.11.27.625600 — neuroscience — Posted on 2024-11-27
449 White matter microstructure links with brain, bodily and genetic attributes in adolescence, mid- and late life
Korbmacher, M.; Tranfa, M.; Pontillo, G.; van der Meer, D.; Wang, M.-Y.; Andreassen, O. A.; Westlye, L. T.; Maximov, I. I.
10.1101/2024.11.27.625603 — neuroscience — Posted on 2024-11-27
450 White matter hyperintensities and microplastics
Bearer, E. L.; Garcia, M. A.; Adolphi, N. L.; Campen, M. J.
10.1101/2024.11.26.625277 — neuroscience — Posted on 2024-11-27
456 Rac1 inhibition prevents axonal cytoskeleton dysfunction in Transthyretin Amyloid Polyneuropathy
Magalhaes, J.; Dias, V.; Eira, J.; Novoa, G.; Oliveira da Silva, M. I.; Kan, Y. Y.; Dias, A.; Carvalho, E.; Santos, M.; Seixas, A. I.; Coelho, T.; Taipa, R.; Paes de Faria, J. I.; Lemos, C.; Liz, M. A.
10.1101/2024.11.27.625664 — neuroscience — Posted on 2024-11-27
458 Sensory Entrained TMS (seTMS) enhances motor cortex excitability
Ross, J. M.; Forman, L.; Gogulski, J. D.; Hassan, U.; Cline, C. C.; Parmigiani, S.; Truong, J.; Hartford, J. W.; Chen, N.-F.; Fujioka, T.; Makeig, S.; Pascual-Leone, A.; Keller, C.
10.1101/2024.11.26.625537 — neuroscience — Posted on 2024-11-27
463 Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
Zhang, L.; Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez Gonzalez, R.; Camacho-Arroyo, I.; Eiden, L. E.; Millar, R. P.
10.1101/2023.09.05.556375 — neuroscience — Posted on 2024-11-27
464 Reprogramming SREBP1-dependent lipogenesis and inflammation in high-risk breast with licochalcone A: a novel path to cancer prevention
Hajirahimkhan, A.; Bartom, E. T.; Chung, C. H.; Guo, X.; Berkley, K.; Lee, O.; Chen, R.; Cho, W.; Chandrasekaran, S.; Clare, S. E.; Khan, S.
10.1101/2024.05.20.595011 — cancer biology — Posted on 2024-11-27
465 Bending DNA increases its helical repeat
Chandrasekhar, S.; Swope, T. P.; Fadaei, F.; Hollis, D. R.; Bricker, R.; Houser, D.; Portman, J.; Schmidt, T. L.
10.1101/2024.02.14.579968 — biophysics — Posted on 2024-11-27
466 Neuroimage Denoiser for removing noise from transient fluorescent signals in functional imaging.
Weissbach, S.; Borghi, M.; Milkovits, J.; Amaral, C.; El Khallouqi, A.; Gerber, S.; Heine, M.
10.1101/2024.06.08.598061 — bioinformatics — Posted on 2024-11-27
467 A new method for a priori practical identifiability
Thompson, P. A.; Andersson, B. J.; Sundqvist, N.; Cedersund, G.
10.1101/2022.10.20.511900 — bioengineering — Posted on 2024-11-27
468 Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster populations
Hubert, D. L.; Arnold, K. R.; Greenspan, Z. G.; Pupo, A.; Robinson, R. D.; Chavarin, V. V.; Barter, T. T.; Djukovic, D.; Raftery, D.; Vue, Z.; Hinton, A.; McReynolds, M. R.; Harrison, B. R.; Phillips, M. A.
10.1101/2024.06.28.601037 — evolutionary biology — Posted on 2024-11-27
470 Comprehensive chemotyping, and the gonadal regulation, of seven kisspeptinergic neuronal populations in the mouse brain
Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez-Gonzalez, R.; Camacho-Arroyo, I. S.; Millar, R. P.; Eiden, L. E.; Zhang, L.
10.1101/2024.07.23.604881 — neuroscience — Posted on 2024-11-27
473 Quantitative mapping of pseudouridines in bacteria RNA
Sharma, S.; Woodworth, B.; Yang, B.; Duan, N.; Pheko, M.; Moutsopoulos, N.; Emiola, A.
10.1101/2024.11.26.625507 — microbiology — Posted on 2024-11-27
474 Engineered CRISPR-Base Editors as a Permanent Treatment for Familial Dysautonomia
Yun, S.; Chekuri, A.; Art, J.; Kondabolu, K.; Slaugenhaupt, S. A.; Zeltner, N.; Kleinstiver, B. P.; Morini, E.; Alves, C. R. R.
10.1101/2024.11.27.625322 — bioengineering — Posted on 2024-11-27
475 High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing
Ntekas, I.; Takayasu, L.; McKellar, D. W.; Grodner, B. M.; Holdener, C.; Schweitzer, P. A.; Sauthoff, M.; Shi, Q.; Brito, I. L.; De Vlaminck, I.
10.1101/2024.11.18.624127 — genomics — Posted on 2024-11-27
476 Structure of dimerized assimilatory NADPH-dependent sulfite reductase reveals the minimal interface for diflavin reductase binding
Ghazi Esfahani, B.; walia, n.; Neselu, K.; Garg, Y.; Aragon, M.; Askenasy, I.; Wei, A.; mendez, j.; Stroupe, M. E.
10.1101/2024.06.14.599029 — molecular biology — Posted on 2024-11-27
478 Persistent legacy effects on soil microbiota facilitate plant adaptive responses to drought
Ginnan, N. A.; Custodio, V.; Gopaulchan, D.; Ford, N.; Salas-Gonzalez, I.; Jones, D. D.; Wells, D. M.; Moreno, A.; Castrillo, G.; Wagner, M. R.
10.1101/2024.08.26.609769 — microbiology — Posted on 2024-11-27
479 Systemic 4-1BB stimulation augments extrafollicular memory B cell formation and recall responses during Plasmodium infection.
Caloba, C.; Sturtz, A.; Lyons, T. A.; John, L.; Ramachandran, A.; Minns, A. M.; Cannon, A. M.; Whalley, J. P.; Watts, T. H.; Kaplan, M.; Lindner, S. E.; Vijay, R.
10.1101/2023.09.12.557411 — immunology — Posted on 2024-11-27
480 Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice
Breant, B. J.; Prius Mengual, J.; Hoerder-Suabedissen, A.; Patel, J.; Bannerman, D. M.; Sharp, T.; Vyazovskiy, V. V.
10.1101/2022.12.11.519886 — neuroscience — Posted on 2024-11-27
482 Tumoral hypoxic extracellular vesicles create a protective microenvironment for triple-negative breast cancer
Pachane, B. C.; Bottaro, P. H. T.; Machado, A. M.; Castro, C. A.; Guerra, G.; Gozzer, L. T.; Grigoli, M. M.; Zutiao, A. D.; Fuzer, A. M.; Cominetti, M. R.; Altei, W. F.; Selistre-de-Araujo, H. S.
10.1101/2024.11.01.621519 — cancer biology — Posted on 2024-11-27
483 Unraveling the GM1 specificity of Galectin-1 binding to lipid membranes
Scollo, F.; Kulig, W.; Nicita, G.; Ludwig, A.-K.; Ricardo, J. C.; Zito, V.; Kapusta, P.; Vattulainen, I.; Cebecauer, M.; Gabius, H.-J.; Kaltner, H.; Maccarrone, G.; Hof, M.
10.1101/2024.09.20.614102 — biophysics — Posted on 2024-11-27
484 Transcription factor prediction using protein 3Dsecondary structures
Liebold, J.; Neuhaus, F.; Geiser, J.; Kurtz, S.; Baumbach, J.; Newaz, K.
10.1101/2024.03.14.585054 — bioinformatics — Posted on 2024-11-27
486 bamSliceR: a Bioconductor package for rapid, cross-cohort variant analysis
Huang, Y. P.; Harmon, L. M.; Gardner, E.; Ma, X.; Harsh, J.; Xue, Z.; Wen, H.; Ramos, M.; Davis, S. R.; Triche, T. J.
10.1101/2023.09.15.558026 — bioinformatics — Posted on 2024-11-27
490 Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
Salgueiro, V.; Bertol, J.; Gutierrez, C.; Serrano-Mestre, J. L.; Ferrer-Luzon, N.; Vazquez-Iniesta, L.; Palacios, A.; Pasquina-Lemonche, L.; Espalliat, A.; Lerma, L.; Weinrick, B.; Lavin, J. L.; Elortza, F.; Azkalgorta, M.; Prieto, A.; Buendia-Nacarino, P.; Luque-Garcia, J. L.; Neyrolles, O.; Cava, F.; Hobbs, J.; Sanz, J.; Prados-Rosales, R.
10.1101/2023.11.19.567727 — microbiology — Posted on 2024-11-27
492 Multispectral live-cell imaging with uncompromised spatiotemporal resolution
Kumar, A.; McNally, K. E.; Zhang, Y.; Haslett-Saunders, A.; Wang, X.; Guillem-Marti, J.; Lee, D.; Huang, B.; Stallinga, S.; Kay, R. R.; Baker, D.; Derivery, E.; Manton, J. D.
10.1101/2024.06.12.597784 — biophysics — Posted on 2024-11-27
493 Dimerization of assimilatory NADPH-dependent sulfite reductase reveals elements for diflavin reductase binding at a minimal interface
Ghazi Esfahani, B.; walia, n.; Neselu, K.; Garg, Y.; Aragon, M.; Askenasy, I.; Wei, A.; mendez, j.; Stroupe, M. E.
10.1101/2024.06.14.599029 — molecular biology — Posted on 2024-11-27
494 Distractor suppression operates exclusively in retinotopic coordinates
Ilksoy, Y. A.; van Moorselaar, D.; Wang, B.; Los, S. A.; Theeuwes, J.
10.1101/2024.02.01.578407 — neuroscience — Posted on 2024-11-27
497 Whole genome CRISPR screens identify a LRRK2-regulated pathway for extracellular tau uptake by human neurons
Evans, L. D.; Strano, A.; Tuck, E.; Campbell, A.; Smith, J.; Hung, C.; Behr, T.; Ghetti, B.; Ryskeldi-Falcon, B.; Karakoc, E.; Iorio, F.; Reith, A.; Bassett, A. R.; Livesey, F.
10.1101/2020.08.11.246363 — neuroscience — Posted on 2024-11-27
498 Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil.
Hubbe, A.; Pestle, W.; Hubbe, M.; Amirali, A.; Chim, E. N.; de Oliveira, R. E.; Pinto Sandoval, E. D.; Duarte, J. M.; Neves, W. A.
10.1101/2024.11.08.621301 — paleontology — Posted on 2024-11-27
502 Successful delivery of CRISPR-Cas9 with a baculovirus vector for insect brain targets
Dogan, B. E. K.; Ghanem, S.; Goblirsch, M.; Nazneen, F.; Broadrup, R. L.; Connolly-Sporing, A.; Tuncer, D.; Mayack, C.
10.1101/2024.11.26.624635 — genetics — Posted on 2024-11-27
503 Platelet Factor 4 (PF4) Regulates Hematopoietic Stem Cell Aging
Zhang, S.; Ayemoba, C. E.; Di Staulo, A. M.; Joves, K.; Patel, C. M.; Leung, E. H. W.; Ong, S.-G.; Nerlov, C.; Maryanovich, M.; Chronis, C.; Pinho, S.
10.1101/2024.11.25.625252 — cell biology — Posted on 2024-11-27
504 Mitochondrial and Microtubule Defects in Exfoliation Glaucoma
Venkatesan, A.; Ridilla, M.; Castro, N.; Wolosin, M.; Henty-Ridilla, J.; Knox, B.; Ganapathy, P.; Brown, J.; DeVincentis, A.; Sieminski, S.; Bernstein, A.
10.1101/2024.11.25.625249 — cell biology — Posted on 2024-11-27
506 Accelerating protein engineering with fitness landscape modeling and reinforcement learning
Sun, H.; He, L.; Deng, P.; Liu, G.; Liu, H.; Cao, C.; Ju, F.; Wu, L.; Qin, T.; Liu, T.-Y.
10.1101/2023.11.16.565910 — synthetic biology — Posted on 2024-11-27
508 PLM-interact: extending protein language models to predict protein-protein interactions
Liu, D.; Young, F.; Lamb, K. D.; Claudio Quiros, A.; Pancheva, A.; Miller, C.; Macdonald, C.; Robertson, D. L.; Yuan, K.
10.1101/2024.11.05.622169 — bioinformatics — Posted on 2024-11-27
509 Quantum Spin Resonance in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells
Abrahams, G. J.; Spreng, V.; Stuhec, A.; Kempf, I.; James, J.; Sechkar, K.; Stacey, S.; Trelles-Fernandez, V.; Antill, L. M.; Ingaramo, M.; York, A. G.; Tetienne, J.-P.; Timmel, C. R.; Steel, H.
10.1101/2024.11.25.625143 — bioengineering — Posted on 2024-11-27
510 Multi-sample non-negative spatial factorization
Wang, Y.; Woyshner, K.; Sriworarat, C.; Stein-O'Brien, G.; Goff, L. A.; Hansen, K. D.
10.1101/2024.07.01.599554 — genomics — Posted on 2024-11-27
512 Performance evaluation of adaptive introgression classification methods
Romieu, J.; Camarata, G.; Crochet, P.-A.; de Navascues, M.; Leblois, R.; Rousset, F.
10.1101/2024.06.12.598278 — evolutionary biology — Posted on 2024-11-27
515 Non-invasive optical synthetization of hearing sensation in non-genetically modified animal
Tamai, Y.; Uenaka, M.; Okamoto, A.; Hosokawa, K.; Ito, Y.; Toda, K.; Hiryu, S.; Kobayasi, K. I.
10.1101/2023.05.13.540641 — neuroscience — Posted on 2024-11-27
518 Unipept in 2024: Expanding metaproteomics analysis with support for missed cleavages, semi-tryptic and non-tryptic peptides
Vande Moortele, T.; Devlaminck, B.; Van de Vyver, S.; Van Den Bossche, T.; Martens, L.; Dawyndt, P.; Mesuere, B.; Verschaffelt, P.
10.1101/2024.09.26.615136 — bioinformatics — Posted on 2024-11-27
523 ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis
Lodhiya, T.; Palande, A.; Veeram, A.; Larrouy-Maumus, G.; Beste, D. J.; Mukherjee, R.
10.1101/2023.09.11.557291 — microbiology — Posted on 2024-11-27
529 Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats
Vazquez, J. M.; Lauterbur, M. E.; Mottaghinia, S.; Bucci, M.; Fraser, D.; Gray-Sandoval, G.; Gaucherand, L.; Haidar, Z. R.; Han, M.; Kohler, W.; Lama, T. M.; Lecorf, A.; Loyer, C.; Maesen, S.; McMillan, D.; Li, S.; Lo, J.; Rey, C.; Capel, S. L.; Singer, M.; Slocum, K.; Thomas, W.; Debelak Tyburec, J.; Santos Villa, S. G.; Miller, R.; Buchalski, M.; Vazquez-Medina, J. P.; Pfeffer, S.; Etienne, L.; Enard, D.; Sudmant, P. H.
10.1101/2024.10.10.617725 — genomics — Posted on 2024-11-27
530 Annotation and assessment of functional variants in regulatory regions using epigenomic data in farm animals
Ma, R.; Kuang, R.; Zhang, J.; Sun, J.; Xu, Y.; Zhou, X.; Han, Z.; Hu, M.; Wang, D.; Fu, Y.; Zhang, Y.; Li, X.; Zhu, M.; Xiang, T.; Zhao, S.; Shi, M.; Zhao, Y.
10.1101/2024.02.06.578787 — genomics — Posted on 2024-11-27
535 A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis
Majumdar, S.; Li, Y.; Manjari, S. R.; Gamper, H. B.; Hou, Y.-M.; Banavali, N. K.; Ojha, A. K.; Agrawal, R. K.
10.1101/2024.11.25.625233 — microbiology — Posted on 2024-11-27
538 Congruent brain signatures specific to phonology in fronto-temporal cortex during language production and understanding.
Dmitrieva, X.; Anton, J.-L.; Runnqvist, E.; Fairs, A.; Ivanova, B.; Sein, J.; Nazarian, B.; Dufour, S.; Pulvermuller, F.; Strijkers, K.
10.1101/2024.09.22.614347 — neuroscience — Posted on 2024-11-27
539 Epromoters bind key stress-related transcription factors to regulate clusters of stress response genes
Malfait, J.; Wan, J.; Singh, H.; Souaid, C.; Farah, G.; Esnault, C.; Sarrazin, S.; Sieweke, M.; Spicuglia, S.
10.1101/2024.11.26.625372 — genomics — Posted on 2024-11-26
540 Insights into the causes and consequences of DNA repeat expansions from 700,000 biobank participants
Hujoel, M. L. A.; Handsaker, R. E.; Kamitaki, N.; Mukamel, R. E.; Rubinacci, S.; Palamara, P. F.; McCarroll, S. A.; Loh, P.-R.
10.1101/2024.11.25.625248 — genetics — Posted on 2024-11-26
541 Arabidopsis PRMT5 Buffers Pre-mRNA Splicing and Development Against Genetic Variation in Donor Splice Sites
Beckel, M. S.; San Martin, A.; Sanchez, S.; Seymour, D. K.; de Leone, M. J.; Careno, D. A.; Mora-Garcia, S.; Weigel, D.; Yanovsky, M. J.; Chernomoretz, A.
10.1101/2024.11.26.624665 — molecular biology — Posted on 2024-11-26
544 Discovery of allodiploid hybrid species Aspergillus latus in Japan
Shibata, S.; Uchida, M.; Ban, S.; Kamei, K.; Watanabe, A.; Yaguchi, T.; Hubka, V.; Takahashi, H.
10.1101/2024.11.25.625089 — microbiology — Posted on 2024-11-26
546 Calcium-mediated amyloid co-aggregation of S100A1 and S100A8 proteins
Karalkeviciute, V.; Baronaite, I.; Pestenyte, A.; Veiveris, D.; Usevicius, G.; Simenas, M.; Ziaunys, M.; Smirnovas, V.; Sulskis, D.
10.1101/2024.11.26.625466 — biochemistry — Posted on 2024-11-26
547 Hepatic HKDC1 Deletion Alleviates Western Diet-Induced MASH in Mice
Xu, K.; Corona-Avila, I.; Frutos, M. D.; Nunez-Sanchez, M. A.; Makhanasa, D.; Shah, P. V.; Guzman, G.; Ramos-Molina, B.; Priyadarshini, M.; Khan, M. W.
10.1101/2024.11.26.625530 — biochemistry — Posted on 2024-11-26
548 Structural Insights into Broad-Range Polyphosphate Kinase 2 II Enzymes Applicable for Pyrimidine Nucleoside Diphosphate Synthesis
Kuge, M.; Keppler, M.; Friedrich, F.; Saleem-Batcha, R.; Winter, J.; Prucker, I.; Germer, P.; Gerhardt, S.; Einsle, O.; Jung, M.; Jessen, H.; Andexer, J. N.
10.1101/2024.11.26.625422 — biochemistry — Posted on 2024-11-26
549 The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks
Song, W.; Zhao, Y.; Ruggiano, A.; Redfield, C.; Newman, j.; Zhu, X.; Cruz-Migoni, A.; Roddan, R.; McHugh, P.; Elliott, P. R.; Ramadan, K.
10.1101/2024.11.26.625361 — biochemistry — Posted on 2024-11-26
551 Yeast elongation factor homolog New1 protects a subset of mRNAs from degradation by no-go decay
Mueller, M.; Tittel, L. S.; Petfalski, E.; Iyer, K. V.; Pastore, S.; Butto, T.; Winz, M.-L.
10.1101/2024.11.26.625534 — molecular biology — Posted on 2024-11-26
552 RNA programmable cell targeting and manipulation with CellREADR
Yang, X.; Woldemichael, K.; Hover, J.; Zhao, S.; Guo, X.; Qian, Y.; Gillis, J.; Huang, Z. J.
10.1101/2024.11.26.625312 — molecular biology — Posted on 2024-11-26
559 In mouse and gut-on-a-chip models, pre-colonoscopy bowel preparation promotes pathogen colonization of the gut and translocation to other organs
Clayton, C. A.; McCallum, G.; Deng, B. D.; Srinivas, A.; Sie, C.; Ng, K. M.; He, J. Y.; Tertigas, D.; Porter, I.; Pepin, D. M.; Fardeen, T.; Sinha, S. R.; Surette, M. G.; Vallance, B. A.; Tropini, C.
10.1101/2024.11.26.625504 — microbiology — Posted on 2024-11-26
561 Carbon-conserving Bioproduction of Malate in an E. coli-based Cell-Free System
Cardiff, R.; Chowdhury, S.; Sugianto, W.; Tickman, B. I.; Alba Burbano, D.; Meyer, P. A.; Cook, M.; King, B.; Garenne, D.; Beliaev, A.; Noireaux, V.; Peralta-Yahya, P.; Carothers, J. M.
10.1101/2024.11.26.623433 — synthetic biology — Posted on 2024-11-26
562 High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes
Peterman, E. L.; Ploessl, D. S.; Love, K. S.; Sanabria, V.; Daniels, R. F.; Johnstone, C. P.; Godavarti, D. R.; Kabaria, S. R.; Pai, A. A.; Galloway, K. E.
10.1101/2024.11.26.625483 — synthetic biology — Posted on 2024-11-26
563 Synthetic ratio computation for programming population composition and multicellular morphology
An, B.; Tang, T.-C.; Zhang, Q.; Wang, T.; Gan, K.; Liu, K.; Liu, Y.; Wang, Y.; Shaw, W. M.; Liang, Q.; Wang, Y.; Lu, T. K.; Church, G. M.; Zhong, C.
10.1101/2024.11.26.624747 — synthetic biology — Posted on 2024-11-26
564 Association between COVID-19 Disease Severity and T Cell Receptor Repertoire
Chen, X.; Su, Y.; Dai, C.; Goldman, J. D.; Heath, J. R.; Liu, S.; Sun, W.
10.1101/2024.11.26.625333 — bioinformatics — Posted on 2024-11-26
565 Growth rate regulates RNA polymerase II transcription elongation in Saccharomyces cerevisiae
Garrido-Godino, A. I.; Martin-Exposito, M.; Gonzalez, R.; Chavez, S.; Perez-Ortin, J. E.; Navarro, F.
10.1101/2024.11.26.625403 — molecular biology — Posted on 2024-11-26
566 Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA)
Smith, R. E.; Christena, R. L.; Michno, B. J.; Davis, J. L.; Lidbury, I. D.; Alaman-Zarate, M.; Stefanidi, D.; Maes, E.; Fisher, H.; Prajsnar, T. K.; Mesnage, S.
10.1101/2024.11.26.625352 — microbiology — Posted on 2024-11-26
567 Developmentally-regulated proteolysis by MdfA and ClpCP mediates metabolic differentiation during Bacillus subtilis sporulation
Riley, E. P.; Lyda, J. A.; Reyes-Matte, O.; Sugie, J.; Kasu, I. R.; Enustun, E.; Armbruster, E.; Ravishankar, S.; Isaacson, R. L.; Camp, A. H.; Garrido, J. L.; Pogliano, K.
10.1101/2024.11.26.625531 — microbiology — Posted on 2024-11-26
568 Quantitative mapping of pseudouridines in bacteria RNA
Sharma, S.; Woodworth, B.; Yang, B.; Duan, N.; Pheko, M.; Moutsopoulos, N.; Emiola, A.
10.1101/2024.11.26.625507 — microbiology — Posted on 2024-11-26
572 The oxidative stress response-related peroxiredoxin Tsa1b of Candida auris functions as a virulence factor that promotes infection
Areitio, M.; Rodriguez-Erenaga, O.; Aparicio-Fernandez, L.; Abio-Dorronsoro, L.; Martin-Souto, L.; Perez-Cuesta, U.; Buldain, I.; Zaldibar, B.; Ruiz-Gaitan, A.; Peman, J.; LeibundGut-Landmann, S.; Rementeria, A.; Antoran, A.; Ramirez-Garcia, A.
10.1101/2024.11.26.625378 — microbiology — Posted on 2024-11-26
574 Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling
Tetenborg, S.; Shihabeddin, E.; Kumar, E. O. A. M.; Sigulinsky, C.; Dedek, K.; Lin, Y.-P.; Echeverry, F.; Hoff, H.; Pereda, A.; Jones, B. W.; Ribelayga, C.; Ebnet, K.; Matsuura, K.; O'Brien, J.
10.1101/2024.11.26.625481 — neuroscience — Posted on 2024-11-26
577 Functional Dichotomy of Orbitofrontal Cortex and Anterior Cingulate Cortex Subregions in Decision-Making and Brain-Body Regulation
Papageorgiou, G. K.; Gibson, D. J.; Amemori, K.-i.; Schwerdt, H. N.; Naim, M.; Wang, M. C.; Yoshida, T.; Sharma, J.; Upadhyay, U.; Yang, G. R.; Graybiel, A. M.
10.1101/2024.11.26.625512 — neuroscience — Posted on 2024-11-26
579 Microglia promote neurodegeneration and hyperkatifeia during withdrawal and prolonged abstinence from chronic binge alcohol
McNair, E.; Dawkins, L.; Ross, G.; Barnett, A.; Nakkala, P.; Qin, L.; Zou, J.; Nikolova, V.; Moy, S.; Coleman, L. G.
10.1101/2024.11.26.625461 — neuroscience — Posted on 2024-11-26
582 Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer
Kövilein, J.; Sorbie, A.; Khaloian, S.; Küntzel, V.; Ahmed, M.; Jarosch, S.; Remke, M.; Metwaly, A.; Reuss, E. M.; Busch, D.; Allez, M.; Steiger, K.; Schraml, B.; Coleman, O. I.; Haller, D.
10.1101/2024.11.25.624835 — cancer biology — Posted on 2024-11-26
583 Deep Learning Unravels Potential Antibiotic-Resistance Drugs against Klebsiella Pneumoniae
Lin, P.; Zhou, J.; Meng, S.; Jin, L.; Qiu, H.; Xu, Y.; Hsu, T.; Bu, Y.; Qin, G.; Zhang, W.
10.1101/2024.11.25.625191 — bioinformatics — Posted on 2024-11-26
585 Quantum Correlations in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells
Abrahams, G. J.; Spreng, V.; Stuhec, A.; Kempf, I.; James, J.; Sechkar, K.; Stacey, S.; Trelles-Fernandez, V.; Antill, L. M.; Ingaramo, M.; York, A. G.; Tetienne, J.-P.; Timmel, C. R.; Steel, H.
10.1101/2024.11.25.625143 — bioengineering — Posted on 2024-11-26
590 A wave of minor de novo DNA methylation initiates in mouse 8-cell embryos and co-regulates imprinted X- chromosome inactivation with H3K27me3
Yue, Y.; Fu, W.; Yang, Q.; Zhang, C.; Wang, W.; Chu, M.; Lyu, Q.; Tang, Y.; Cui, J.; Wang, X.; Zhang, Z.; Tian, J.; An, L.
10.1101/2023.10.06.561284 — developmental biology — Posted on 2024-11-26
591 Sex chromosomes shape the transcriptional landscape of the preimplantation mouseembryo
Snell, D. M.; Varsally, W.; Courtois, A.; Menchero, S.; Munusamy, P.; Rietdijk, R.; Ojarikre, O. A.; Strohbuecker, S.; Kaya, H.; Sangrithi, M. N.; Turner, J. M.
10.1101/2024.11.26.625424 — developmental biology — Posted on 2024-11-26
592 The Integrator complex prevents premature neuronal differentiation through global control of transcription elongation.
Somsen, H. B.; Eigenhuis, K. N.; Kuijpers-Korporaal, A. L.; Pelicano de Almeida, M.; Montoro Ferrer, R.; Kats, K.; Dekker, M. R.; Zuidweg, T.; Azmani, Z.; van den Hout, M. C. G. N.; van IJcken, W. F. J.; Huylebroeck, D.; Fornerod, M.; Poot, R. A.; van den Berg, D. L. C.
10.1101/2024.11.26.625369 — developmental biology — Posted on 2024-11-26
594 Mechanism of MCUB-dependent inhibition of mitochondrial calcium uptake
Rai, N. K.; Balynas, A. M.; MacEwen, M. J.; Bratt, A. R.; Sancak, Y.; Chaudhuri, D.
10.1101/2024.11.25.625228 — cell biology — Posted on 2024-11-26
595 Enhanced immunogenicity of a Clostridioides difficile TcdB vaccine adjuvanted with a synthetic dual-TLR ligand adjuvant.
Naz, F.; Hagspiel, N.; Xu, F.; Thompson, B.; Moreau, G. B.; Young, M.; Herbein, J.; Fox, C. B.; Petri, W. A.; Abhyankar, M. M.
10.1101/2024.11.25.625229 — immunology — Posted on 2024-11-26
596 Neutrophil-chemoattractant CXCL5 induces lung barrier permeability in acute lung injury
Berger, S.; Goekeri, C.; Pennitz, P.; Gutbier, B.; Michalick, L.; Hoffmann, K.; Lopez-Rodriguez, E.; Gluhovic, V.; Wienhold, S.-M.; Behrendt, U.; Taylor, A.; Dietert, K.; Kirsten, H.; Kunder, S.; Mueller, K.; Weigel, M.; Hain, T.; Volkers, S. M.; Weis, S.; Gruber, A. D.; Sander, L. E.; Kuebler, W. M.; CAPSyS study group, ; Witzenrath, M.; Nouailles, G.
10.1101/2024.11.25.625215 — immunology — Posted on 2024-11-26
597 Eosinophils promote monocyte to macrophage differentiation and anti-bacterial immunity
Wilson, G. J.; Foley, L. K.; Pocalun, Z.; Pitmon, E.; Fukuoka, A.; Lee, K. M.; Fernandez, L.; Mathie, H.; Bartolini, R.; Cole, J. J.; Graham, G.
10.1101/2024.11.25.625164 — immunology — Posted on 2024-11-26
598 Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of APP NL-G-F mice
Rodriguez, G. A.; Rothenberg, E. F.; Shetler, C. O.; Aoun, A.; Posani, L.; Vajram, S. V.; Tedesco, T.; Fusi, S.; Hussaini, S. A.
10.1101/2024.11.26.624990 — neuroscience — Posted on 2024-11-26
600 Procrustes Alignment in Individual-level Analyses of Functional Gradients
Sasse, L.; Paquola, C.; Dukart, J.; Hoffstaedter, F.; Eickhoff, S. B.; Patil, K. R.
10.1101/2024.11.26.625368 — neuroscience — Posted on 2024-11-26
602 Neurogenetic evidence for oscillatory behavior of Lgr3-positive growth control interneurons in Drosophila
Zanini, R.; Pereirinha, J.; Fernandez-Acosta, M.; Casimiro, A. P.; Pinho, M.; Garelli, A.; Heredia, F.; Gontijo, A. M.
10.1101/2024.11.26.625404 — neuroscience — Posted on 2024-11-26
604 Anatomy, histology and ultrastructure of the adult human olfactory peduncle: blood vessel and corpora amylacea assessment
Raspeno-Garcia, J.; Gonzalez-Granero, S.; Herranz-Perez, V.; Cozar-Cuesta, A. i.; Artacho-Perula, E.; Insausti, R.; Garcia-Verdugo, J. M.; de la Rosa, C.
10.1101/2024.11.26.625157 — neuroscience — Posted on 2024-11-26
605 Behaviorally-relevant features of observed actions dominate cortical representational geometry in natural vision
Han, J.; Chauhan, V.; Philip, R.; Taylor, M. K.; Jung, H.; Halchenko, Y. O.; Gobbini, M. I.; Haxby, J. V.; Nastase, S. A.
10.1101/2024.11.26.624178 — neuroscience — Posted on 2024-11-26
607 Cortical assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects
Walsh, R. M.; Crabtree, G. W.; Kalpana, K.; Jubierre, L.; Koo, S. Y.; Ciceri, G.; Gogos, J.; Kruglikov, I.; Studer, L.
10.1101/2024.11.26.624368 — neuroscience — Posted on 2024-11-26
608 Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping
Tucciarelli, R.; Bird, L.; Straka, Z.; Szymanska, M.; Kollamkulam, M.; Sonar, H.; Paik, J.; Clode, D.; Hoffmann, M.; Cowie, D.; Makin, T. R.
10.1101/2024.11.26.624817 — neuroscience — Posted on 2024-11-26
612 CalliCog: an open-source cognitive neuroscience toolkit for freely behaving nonhuman primates
Scott, J.; Vasquez, B. M.; Stewart, B.; Panacheril, D.; Rajit, D.; Fan, A.; Bourne, J.
10.1101/2024.11.26.625450 — neuroscience — Posted on 2024-11-26
614 Adolescent-like Processing of Behaviorally Salient Cues in Sensory and Prefrontal Cortices of Adult Preterm-Born Mice
McCoy, E.; Pendala, V.; Fariborzi, M.; Demir, L.; Buell, O.; Fedde, S.; Stinger, J.; Elbaum, L.; Holsworth, T.; Amenyo-Awude, P.; Ribic, A.
10.1101/2024.11.26.625455 — neuroscience — Posted on 2024-11-26
620 Atrial Granules in Atrial Cardiomyocytes as Acidic Calcium Stores
Akerman, E.; Aston, D.; Rog-Zielinska, E.; Boland, B.; Schotten, U.; Verheule, S.; Capel, R. A.; Burton, R. A. B.
10.1101/2024.11.25.625237 — physiology — Posted on 2024-11-26
621 Lysosomal calcium signalling contributes to the acute α-adrenergic response via calcium-stimulated adenylyl cyclase 1 and 8
Akerman, E.; Capel, R. A.; Read, M.; Song, Q.; Bose, S. J.; Calamaio, S.; Aston, D.; Koschinski, A.; Lloyd, S.; Bell, L.; Rashbrook, V. S.; Keller, M.; Bracher, F.; Potter, B. V.; Rivolta, I.; Galione, A.; Sparrow, D. B.; Conti, A.; Terrar, D. A.; Zaccolo, M.; Burton, R. A. B.
10.1101/2024.11.25.625232 — physiology — Posted on 2024-11-26
622 A QbD strategy to develop curcumin and siRNA co-loaded lipoplexes to combat osteoarthritis-related inflammation and oxidative stress
Ranamalla, S. R.; Porfire, A.; Licarete, E.; Tefas, L.; Parvathaneni, R. P.; Varghese, O.; Sesarman, A.; Focsan, M.; Tudoran, L. B.; Tomuta, I.; Banciu, M.
10.1101/2024.11.25.625050 — pharmacology and toxicology — Posted on 2024-11-26
625 Stepwise Assembly Of Crown Reptile Anatomy Clarified By Late Paleozoic Outgroups Of Neodiapsida
Jenkins, X.; Benson, R. B. J.; Ford, D. P.; Browning, C.; Fernandez, V.; Dollman, K.; Gomes, T.; Griffiths, E.; Choiniere, J. N.; Peecook, B. R.
10.1101/2024.11.25.625221 — paleontology — Posted on 2024-11-26
626 CD47 predominates over CD24 as a macrophage immune checkpoint in cancer.
Allen, J.; Meglan, A.; Vaccaro, K.; Velarde, J.; Chen, V.; Ribeiro, J.; Blandin, J.; Gupta, S.; Mishra, R.; Ho, R.; Love, J.; Reinhardt, F.; Bell, G. W.; Chen, J.; Weinberg, R.; Yang, D.; Weissman, J.; Weiskopf, K.
10.1101/2024.11.25.625185 — cancer biology — Posted on 2024-11-26
634 The mechanical anisotropy of adipose tissues regulates ovarian cancer invasion
Gonzalez-Molina, J.; Nabili, P.; Marciano, D.; Abdelnabi, S.; Gultekin, O.; Rasul, M. F.; Zhang, Y.; Nadal, C.; Chrysanthou, A.; Alkasalias, T.; Salehi, S.; Balkwill, F. R.; Lehti, K.; Gautrot, J.
10.1101/2024.11.25.625153 — bioengineering — Posted on 2024-11-26
635 Directed Evolution of a Genetically Encoded Indicator for Chloride
Peng, W.; Tutol, J.; Phelps, S.; Kam, H.; Lynd, J.; Dodani, S. C.
10.1101/2024.11.25.624492 — biochemistry — Posted on 2024-11-26
638 Unlocking the Secrets of Amphibious Plant Adaptation: The Role of RNA Modifications
Mazdziarz, M. A.; Krawczyk, K.; Szablinska-Piernik, J.; Paukszto, L.; Szczecinska, M.; Sulima, P.; Sawicki, J.
10.1101/2024.11.25.625166 — genetics — Posted on 2024-11-26
639 Elevational and Oceanic Barriers Shape the Distribution, Dispersal and Diversity of Aotearoa's Kapokapowai (Uropetala) Dragonflies
Tolman, E. R.; Beatty, C. D.; Goodman, A. G.; Ramchand, P.; McAllister, T.; Reyes, K.; Zahara, A.; Taveras, K.; Wade, V.; Abbott, J.; Frandsen, P. B.; Guralnick, R.; Kohli, M. K.; Ware, J. L.; Suvorov, A.
10.1101/2024.11.25.625207 — evolutionary biology — Posted on 2024-11-26
642 Intraspecific and intraindividual trait variability decrease with tree species richness in a subtropical tree biodiversity experiment
Castro Sanchez-Bermejo, P.; Carmona, C. P.; Schuman, M. C.; Benavides, R.; Sachsenmaier, L.; Li, S.; Liu, X.; Haider, S.
10.1101/2024.11.24.625116 — ecology — Posted on 2024-11-26
645 Effects of Primed Adipose Mesenchymal Stem Cell-Derived Exosomes on Immunomodulation in Behcet Uveitis
Gozel, M.; Aydemir, D.; Kaleli, H. N.; Cosar, F.; Guleser, U. Y.; Kusan Unlu, E.; Kesim, C.; Sezgin, B.; Sahin, A.; Ucar, D.; Hatemi, G.; Hasanreisoglu, M.
10.1101/2024.11.24.625042 — immunology — Posted on 2024-11-26
646 Differentiation of related events in hippocampus supports memory reinstatement in development
Varga, N. L.; Roome, H. E.; Molitor, R. J.; Martinez, L.; Hipskind, E. M.; Mack, M. L.; Preston, A. R.; Schlichting, M. L.
10.1101/2023.05.25.541743 — neuroscience — Posted on 2024-11-26
648 OsbHLH089 and OsbHLH094 Modulate OsSLR1 Levels to Maintain Male Reproductive Fitness in Rice
Fernandes, T.; Barros, P. M.; Flores-Tornero, M.; Carvalho, P.; Sapeta, H.; Becker, J. D.; Abreu, I. A.
10.1101/2024.11.24.624999 — plant biology — Posted on 2024-11-26
649 Molecular architecture of thylakoid membranes within intact spinach chloroplasts
Wietrzynski, W.; Lamm, L.; Wood, W. H. J.; Loukeri, M.-J.; Malone, L.; Peng, T.; Johnson, M. P.; Engel, B. D.
10.1101/2024.11.24.625035 — plant biology — Posted on 2024-11-26
655 Identification of novel drug-drug interactions: towards precision medicine in women's reproductive health
Garcia-Acero, P.; Henarejos-Castillo, I.; Sebastian-Leon, P.; Parraga-Leo, A.; Garcia-Velasco, J. A.; Diaz-Gimeno, P.
10.1101/2024.11.25.624843 — pharmacology and toxicology — Posted on 2024-11-26
657 Immune organization in sentinel lymph nodes of melanoma patients is prognostic of distant metastases
Amitay, Y.; Milo, I.; Keidar-Haran, T.; Deis, S.; Truzman, G.; Elhanani, O.; Salame, T. M.; Azimov, M.; Stein, I.; Cohen, J.; Lotem, M.; Pikarsky, E.; Keren, L.
10.1101/2024.11.24.625041 — cancer biology — Posted on 2024-11-26
667 Lineage-specific trait variation generates widespread, contemporaneous coexistence and competitive exclusion dynamics in an invasive, multihost wildlife parasite
Garner, T. W.; Harrison, X. A.; Fenton, A.; Ghosh, P. N.; Verster, R.; Murray, K. A.; Brookes, L. M.; Allen, B. E.; Farrer, R. A.; Schmidt, B. R.; Bates, K. A.; Kruger, N.; Wolmarans, A.; Bosch, J.; Fisher, M. A.; Weldon, C.
10.1101/2024.11.24.625051 — ecology — Posted on 2024-11-26
670 Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction
Ricciotti, E.; Haines, P.; Beerens, M.; Kartoun, U.; Castro, C.; Tang, S. Y.; Ghosh, S.; Das, U.; Lahens, N.; Wang, T.; Griffin, J.; Shaw, S.; Macrae, C.; FitzGerald, G. A.
10.1101/2024.09.28.615616 — pharmacology and toxicology — Posted on 2024-11-26
671 Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia
Snoke, D. B.; van der Velden, J. L.; Bellefleur, E. R.; Dearborn, J. S.; Lenahan, S. M.; Heininger, S. C. J.; Ather, J. L.; Sarausky, H.; Stephenson, D.; Reisz, J. A.; D'Alessandro, A.; Majumdar, D.; Ahern, T. P.; Sandler, K. L.; Landman, B. A.; Janssen-Heininger, Y. M. W.; Poynter, M. E.; Seward, D. J.; Toth, M. J.
10.1101/2024.09.27.615385 — cancer biology — Posted on 2024-11-26
672 Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture
Fukai, Y.; Kujirai, T.; Wakamori, M.; Kanamura, S.; Yamauchi, L.; Zeraati, S.; Tanegashima, C.; Kadota, M.; Kurumizaka, H.; Umehara, T.; Kawaguchi, K.
10.1101/2024.11.08.622658 — biophysics — Posted on 2024-11-26
678 Analysis of the ubiquitin-modified proteome identifies novel host factors in Kaposi's sarcoma herpesvirus lytic reactivation
Causey, A.; Constantine, M.; Oswald, J.; Dellomo, A.; Masters, B.; Omorogbe, E.; Garzino-Demo, A.; Admon, A.; Ehrlich, E. S.
10.1101/2022.08.14.503934 — microbiology — Posted on 2024-11-26
679 Glioblastoma and other intracranial tumors elicit systemic sympathetic hyperactivity that limits immunotherapeutic responses
Lorrey, S. J.; Wachsmuth, L.; Finlay, J.; Neff, C.; Ayasoufi, K.; Waibl Polania, J.; Hoyt-Miggelbrink, A.; Price, M.; Rein, L.; Dell, S.; Reesman, R.; Cui, X.; Hawley, A.; Lerner, E.; Wilkinson, D.; Srinivasan, E.; Walsh, K.; Patel, A.; Ostrom, Q. T.; Fecci, P. E.
10.1101/2023.11.02.565368 — immunology — Posted on 2024-11-26
681 A web-based histology atlas for the freshwater sentinel species Daphnia magna
Ngu, M. S.; Vanselow, D. X.; Zaino, C. R.; Lin, A. Y.; Copper, J. E.; Beaton, M.; Orsini, L.; Colbourne, J. K.; Cheng, K. C.; Ang, K. C.
10.1101/2022.03.09.483544 — zoology — Posted on 2024-11-26
682 Dynamic whole-body models for infant metabolism
Zaunseder, E.; Mohammad, F. K.; Muetze, U.; Koelker, S.; Heuveline, V.; Thiele, I.
10.1101/2024.11.25.625291 — systems biology — Posted on 2024-11-26
685 Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use
Barekat, K.; Ricciotti, E.; Ghosh, S.; Herrmann, C.; Keat, K.; Assenmacher, C.-A.; Tanes, C.; Wilson, N.; Sengupta, A.; Das, U. S.; Joshi, R.; Ritchie, M.; Bittinger, K.; Weljie, A.; Cadwell, K.; Bushman, F.; Wu, G.; FitzGerald, G. A.
10.1101/2024.11.22.624882 — pharmacology and toxicology — Posted on 2024-11-26
686 Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil.
Hubbe, A.; Pestle, W.; Hubbe, M.; Amirali, A.; Chin, E. N.; de Oliveira, R. E.; Pinto Sandoval, E. D.; Duarte, J. M.; Neves, W. A.
10.1101/2024.11.08.621301 — paleontology — Posted on 2024-11-26
688 Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo
Berkamp, S.; Jungbluth, L.; Katranidis, A.; Mostafavi, S.; Korculanin, O.; Lu, P.-H.; Sharma, L.; Thukral, L.; Fitter, J.; Dunin-Borkowski, R. E.; Sachse, C.
10.1101/2024.10.15.618463 — biophysics — Posted on 2024-11-26
692 Genomes of two invasive Adelges species (hemlock woolly adelgid and pineapple gall adelgid) enable characterization of nicotinic acetylcholine receptors
Glendening, A. M.; Stephens, C.; Vuruputoor, V. S.; Stern, D. L.; Hogenhout, S. A.; Mathers, T. C.; Chaganti, T.; Pauloski, N.; Cernak, T. A.; Wegrzyn, J. L.; Fetter, K. C.
10.1101/2024.11.21.624573 — genomics — Posted on 2024-11-26
693 mRNA psi profiling using nanopore DRS reveals cell type-specific pseudouridylation
McCormick, C. A.; Meseonznik, M.; Qiu, Y.; Fanari, O.; Thomas, M.; Liu, Y.; Bloch, D.; Klink, I. N.; Jain, M.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2024.05.08.593203 — genomics — Posted on 2024-11-26
694 Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess neuronal epitranscriptome plasticity
Fanari, O.; Tavakoli, S.; Qiu, Y.; Makhamreh, A.; Nian, K.; Akeson, S.; Meseonznik, M.; McCormick, C. A.; Bloch, D.; Gamper, H.; Jain, M.; Hou, Y.-M.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2024.03.26.586895 — genomics — Posted on 2024-11-26
696 Natural variation in the drug-binding residues of bacterial ribosomes
Ekemezie, C. L.; Chan, L. I.; Brown, C. R.; Helena-Bueno, K.; Williams, T.; Melnikov, S. V.
10.1101/2024.10.31.621234 — evolutionary biology — Posted on 2024-11-26
700 Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry
Eggeler, F.; Boulanger-Weill, J.; De Santis, F.; Belleri, L.; Duroure, K.; Auer, T. O.; Albadri, S.; Del Bene, F.
10.1101/2023.11.23.568438 — developmental biology — Posted on 2024-11-26
702 PEX14 functions as a molecular link between optineurin and pexophagy in human cells
Li, H.; Chen, S.; Lismont, C.; Vandewinkel, B.; Hussein, M. A. F.; Costa, C. F.; Imberechts, D.; Liu, Y.; Vandenberghe, W.; Azevedo, J. E.; Verhelst, S.; Baes, M.; Fransen, M.
10.1101/2024.05.31.596776 — cell biology — Posted on 2024-11-26
703 A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis
Majumdar, S.; Li, Y.; Manjari, S. R.; Gamper, H. B.; Hou, Y.-M.; Banavali, N. K.; Ojha, A. K.; Agrawal, R. K.
10.1101/2024.11.25.625233 — microbiology — Posted on 2024-11-26
706 AvianLexiconAtlas: A database of descriptive categories of English-language bird names around the world
Morrison, E. S.; Pandolfi, G. P.; Aguillon, S. M.; Ali, J. R.; Archard, O.; Baldassarre, D. T.; Baquero, I.; Bennett, K. F. P.; Bonney, K. M.; Bryant, R.; Catanach, R. M.; Catanach, T. A.; Chavoshan, I.; Davis, S. N.; Goodman, B. D.; Gulson-Castillo, E. R.; Hack, M.; Hudon, J.; Leighton, G. M.; Long, K. M.; Ma, Z.; McCoy, D. E.; McLaughlin, J. F.; Rueda Moreno, G.; Mota, T. M.; Noguchi, L.; Nwigwe, U.; Pegan, T.; Provost, K.; Rasband, S. A.; Salter, J. F.; Silvernail, L. C.; Simard, J. A.; Skeen, H. R.; Soto-Patino, J.; Suh, Y. H.; Wang, Q.; Warshauer, M. E.; Yan, S.; Zalinski, B.; Zhao, Z.; S
10.1101/2024.09.13.612884 — zoology — Posted on 2024-11-26
707 Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms
Hijazi, H.; Manessier, J.; Brugiere, S.; Ravnsborg, T.; Courcon, M.; Brule, B.; Merienne, K.; Jensen, O. N.; Hesse, A.-M.; Bruley, C.; Pflieger, D.
10.1101/2024.11.13.623238 — biochemistry — Posted on 2024-11-26
709 The accelerating exposure of European protected areas to climate change
Cimatti, M.; Mezzanotte, V.; Heikkinen, R.; Hallfors, M.; Karger, D. N.; Di Marco, M.
10.1101/2024.11.25.625168 — ecology — Posted on 2024-11-26
710 Compressive stress drives morphogenetic apoptosis through lateral tension and Piezo1
Merle, T.; Cazales, M.; Bouzignac, R.; Ronsin, B.; Rouviere, C.; Mangeat, T.; Suzanne, M.
10.1101/2024.02.08.579454 — developmental biology — Posted on 2024-11-26
711 SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection
Richards, A.; Khalil, A.; Friesen, M.; Whitfield, T.; Lungjangwa, T.; Gehrke, L.; Wan, Z.; Gao, X.; Kamm, R.; Mooney, D.; Jaenisch, R.
10.1101/2023.08.06.552160 — microbiology — Posted on 2024-11-26
712 Inflammation in Areas of Fibrosis Precedes Loss of Kidney Function in Lupus Nephritis
Malvica, S.; Fenaroli, P.; Lee, C.-Y.; Louis, S.; Celia, A. I.; Bagnasco, S.; Yang, X.; Hodgin, J. B.; Buyon, J.; Magder, L.; Petri, M.; Accelerating Medicines Partnership: RA/SLE Network, ; Rosenberg, A.; Fava, A.
10.1101/2024.11.25.625225 — immunology — Posted on 2024-11-26
717 Engaging cancer patients on their attitudes towards microbiome engineering technologies
Owen, K. A.; Rutter, J. W.; Holland, C.; Le, H. T.; Shapira, P.; Lewis, C.; Kinross, J. M.; Barnes, C. P.
10.1101/2024.11.25.625255 — scientific communication and education — Posted on 2024-11-26
719 Mitochondrial respiratory capacity in kidney podocytes is high, age-dependent, and sexually dimorphic.
Campbell, M. D.; Sanchez-Contreras, M. Y.; Sibley, B. D.; Keiser, P.; Ruiz-Sanchez, C.; Mann, C. N.; Marcinek, D.; Najafian, B.; Sweetwyne, M. T.
10.1101/2024.11.24.625104 — cell biology — Posted on 2024-11-26
720 Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models
Bedia, J. S.; Huang, Y.-W.; Gonzalez, A. D.; Gonzalez, V. D.; Funingana, I.-G.; Rahil, Z.; Mike, A.; Lowar, A.; Vias, M.; Ashworth, A.; Brenton, J. D.; Fantl, W. J.
10.1101/2024.11.21.624591 — cancer biology — Posted on 2024-11-26
723 Bwa, an ortholog of alkaline ceramidase-ACER2, promotes intestinal stem cell proliferation through pro-inflammatory cytokine signaling in Drosophila melanogaster
Rahman, M. M.; Kraft, C.; Clark, C.; Nicholson, R.; Marchetti, M.; Williams, E.; Zhang, C.; Holland, W.; Summers, S. A.; Edgar, B. A.
10.1101/2024.11.26.624044 — cell biology — Posted on 2024-11-26
725 HSV-1 infection induces a downstream-shift of the +1 nucleosome
Weiss, E.; Whisnant, A. W.; Hennig, T.; Djakovic, L.; Doelken, L.; Friedel, C. C.
10.1101/2024.03.06.583707 — bioinformatics — Posted on 2024-11-26
726 AI-driven Classification of Heart Failure Preserved and Reduced Ejection Fraction Patients Using the Total Protein Approach
Lenzi, A.; Carvalho, L. B.; Teigas-Campos, P. A. D.; Biagini, D.; Ghimenti, S.; Armenia, S.; Pugliese, N. R.; Masi, S.; Francesco, F. d.; Lomonaco, T.; Lodeiro, C.; Capelo, J. L.; Santos, H. M.
10.1101/2024.11.25.625184 — biochemistry — Posted on 2024-11-26
728 An operational framework to map Essential Life Support Areas (ELSAs) for biodiversity, climate, and sustainable development
Venter, O.; Ervin, J.; Stilger Virnig, A. L.; Consaul Atkinson, S.; Marigo, M.; Zhang, D.; Supples, C.; Paniagua, E.; Phillips, L.; Schuster, R.; Llano, X.; Pence, G.; Arcese, P.; de Assis Barros, L.; Belgubayeva, A.; Borja, D.; Brumby, S.; Burgess, N. D.; Cardozo, L.; Cordero Vega, C.; Cordova, M. V.; Corzo, L.; Delgado, E.; Fonseca, C.; Game, E.; Georges, Y.; Grantham, H.; Guerra, D.; Hansen, A.; Hawley-McMaster, G.; Hout, N.; Jallah, B. S.; KC, D.; Llactayo Leon, W.; Leslie, J.; Lihong, D.; Llosa, C.; Mahmood, A. R. J.; Makholela, T.; Mathis, M.; Miller Granados, C.; McGowan, J.; Monge, R.;
10.1101/2024.11.25.625159 — ecology — Posted on 2024-11-26
732 Pseudomonas aeruginosa-mediated cardiac dysfunction is driven by extracellular vesicles released during infection
Rajaram, M. V. S.; Kumar, N.; Mattoo, S. S.; Sanghvi, S.; Mahajan, S.; Planner, C.; Bednash, J. S.; Khan, M.; Ganesan, L. P.; Singh, H.; Lafuse, W. P.; Wozniak, D. J.
10.1101/2024.11.22.624948 — immunology — Posted on 2024-11-26
734 Failed Double-Blind Replication of Offline 5Hz-rTUS-Induced Corticospinal Excitability
Fong, P.-Y.; Kop, B. R.; Evans, C.; Wijaya, V. G.; Lin, Y.; Cappotto, D.; Lee, J. S. A.; Latorre, A.; Song, J.; Treeby, B. E.; Martin, E.; Rothwell, J.; Verhagen, L.; Bestmann, S.
10.1101/2024.11.25.625187 — neuroscience — Posted on 2024-11-26
735 Cell-type specific responses to single-pulse electrical stimulation of the human brain
Cowan, R. L.; Davis, T. S.; Merricks, E. M.; Kundu, B.; Shofty, B.; Rahimpour, S.; Schevon, C. A.; Rolston, J. D.; Smith, E. H.
10.1101/2024.11.24.625077 — neuroscience — Posted on 2024-11-26
736 Bridging the Python Training Gap for Bioscientists in Brazil: Improvements and Challenges
Crestana, G. S.; Batista, U. d. S.; Funnicelli, M. I. G.; Braga, L. G.; Zuvanov, L.; Bizarria, R.; de Sousa, R. M.; Ferreira, P. H. N.; Winck, F. V.; Margarido, G. R. A.; Varani, A. d. M.; Riano-Pachon, D. M.; Santos, R. A. C.
10.1101/2024.11.25.624749 — scientific communication and education — Posted on 2024-11-26
737 Leg immobilization and subsequent recovery resistance training affect skeletal muscle angiogenesis related markers in young healthy adults regardless of prior resistance training experience
McIntosh, M. C.; Michel, J. M.; Godwin, J. S.; Plotkin, D. L.; Anglin, D. A.; Mattingly, M. L.; Agyin-Birikorang, A.; Kontos, N. J.; Baweja, H. S.; Stock, M. S.; Mobley, C. B.; Roberts, M. D.
10.1101/2024.11.24.625075 — physiology — Posted on 2024-11-26
738 Sirt5 preserves cardiac function in ischemia-reperfusion injury by inhibiting ANT2 lactylation
Zhang, L.; Shi, D.-L.; Yu, L.; Li, S.; Shen, S.; Hong, Y.; Ding, K.; Chen, S.; Chen, J.; Wen, Y.; Wang, C.; Mo, G.
10.1101/2024.11.25.625148 — pathology — Posted on 2024-11-26
740 Recommendations for Bioinformatics in Clinical Practice
Lavrichenko, K.; Engdal, E. S.; Marvig, R. L.; Jemt, A.; Vignes, J. M.; Almusa, H.; Saether, K. B.; Briem, E.; Caceres, E.; Elvarsdottir, E. M.; Gislason, M. H.; Haanpaa, M. K.; Henmyr, V.; Hotakainen, R.; Kaasinen, E.; Kanninga, R.; Khan, S.; Lie-Nielsen, M. G.; Madsen, M. B.; Mahler, N.; Maqbool, K.; Neethiraj, R.; Nyren, K.; Paavola, M.; Pruisscher, P.; Sheng, Y.; Singh, A. K.; Srivastava, A.; Stautland, T. K.; T. Andreasen, D.; ten Berk de Boer, E.; Vang, S.; Wirta, V.; Bagger, F. O.
10.1101/2024.11.23.624993 — bioinformatics — Posted on 2024-11-26
742 Priming Epigenetic Landscape at Gene Promoters through Transcriptional Activation in Mammalian Germ Cells
Li, P.; Fujisawa, T.; Narita, H.; Uneme, Y.; Seki, M.; Hu, M.; Narumi, R.; Namekawa, S. H.; Khan, S. S.; Davie, J. R.; Suzuki, Y.; Adachi, J.; Ashraf, A.; Inoue, A.; Siomi, M. C.; Yamanaka, S.
10.1101/2024.11.24.625111 — genomics — Posted on 2024-11-26
743 Embryonic Signatures of Intergenerational Inheritance across Paternal Environments and Genetic Backgrounds
Dura, M.; Ranjan, B.; Paribeni, R.; Paribeni, V.; Serrano, J. B.; Villacorta, L.; Benes, V.; Boruc, O.; Boskovic, A.; Hackett, J. A.
10.1101/2024.11.25.624914 — genomics — Posted on 2024-11-26
745 Th1 cells are critical tissue organizers of myeloid-rich perivascular activation niches.
Bala, N.; McGurk, A.; Carter, E.; Sidhu, I.; Niak, S.; Leddon, S.; Fowell, D. J.
10.1101/2024.11.24.625073 — immunology — Posted on 2024-11-26
746 Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells
Leu, J.-S.; Deng, H.; Tran, H. N.; Wei, X.; Hashiomoto, C.; Leonard, F.; Wong, T.; Abdelfattah, N.; Benitez Salazar, J. M.; Kang, R.; Maldonado, J. A.; Cristobal, C. D.; Lee, H. K.; An, Z.; Zhang, N.; Yun, K.
10.1101/2024.11.24.624743 — cancer biology — Posted on 2024-11-26
747 Autophagy inhibition induces AML cell death and enhances the efficacy of chemotherapy under hypoxia
Wang, E. S.; Fay, H. R. S.; Dykstra, K. M.; Phelps, M. N.; Johnson, M.; Harrigan, A.; Giorgi, M. C.
10.1101/2024.11.24.625107 — cancer biology — Posted on 2024-11-26
749 Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function
Diwan, A.; Rawnsley, D. R.; Islam, M.; Zhao, C.; Kargar Gaz Kooh, Y.; Mendoza, A.; Navid, H.; Kumari, M.; Guan, X.; Murphy, J. T.; Nigro, J.; Kovacs, A.; Mani, K.; Huebsch, N.; Ma, X.
10.1101/2024.11.24.624947 — cell biology — Posted on 2024-11-26
750 Analysis of a hypomorphic mei-P26 mutation reveals developmental control of CO patterning mechanisms
Berent, E.; Solomon, A.; Spencer, A. P.; Bautista, O.; Terry, J.; Ables, E. T.; Crown, K. N.
10.1101/2024.11.22.624911 — genetics — Posted on 2024-11-25
751 Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System
Imam, F. T.; Gillespie, T. H.; Ziogas, I.; Surles-Zeigler, M. C.; Tappan, S.; Ozyurt, B.; Boline, J.; de Bono, B.; Grethe, J. S.; Martone, M. E.
10.1101/2024.10.25.620360 — bioinformatics — Posted on 2024-11-26
756 Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos
Finnerty, R. M.; Carulli, D. J.; Hedge, A.; Wang, Y.; Boadu, F.; Winuthayanon, S.; Cheng, J.; Winuthayanon, W.
10.1101/2024.06.13.598905 — cell biology — Posted on 2024-11-25
758 Antigen presentation by tumor-associated macrophages drives tumor-infiltrating T cells from a progenitor exhaustion state to terminal exhaustion
Waibl Polania, J.; Hoyt-Miggelbrink, A. M.; Tomaszewski, W. H.; Wachsmuth, L. P.; Lorrey, S. J.; Wilkinson, D. S.; Lerner, E. C.; Woroniecka, K.; Finlay, J. B.; Ayasoufi, K.; Fecci, P. E.
10.1101/2023.08.11.553007 — immunology — Posted on 2024-11-25
759 Deficiency of Orexin Receptor Type 1 in Dopaminergic Neurons Increases Novelty-Induced Locomotion and Exploration
Xiao, X.; Yeghiazaryan, G.; Eggersmann, F.; Cremer, A. L.; Backes, H.; Kloppenburg, P.; Hausen, A. C.
10.1101/2023.08.06.552140 — neuroscience — Posted on 2024-11-25
761 Development of cell-free platforms for discovering, characterizing, and engineering post-translational modifications
Wong, D. A.; Shaver, Z. M.; Cabezas, M. D.; Daniel-Ivad, M.; Warfel, K. F.; Prasanna, D. V.; Sobol, S. E.; Fernandez, R.; Nicol, R.; DeLisa, M. P.; Balskus, E. P.; Karim, A. S.; Jewett, M. C.
10.1101/2024.03.25.586624 — synthetic biology — Posted on 2024-11-25
763 Structural diversity and oligomerization of bacterial ubiquitin-like proteins
Gong, M.; Ye, Q.; Gu, Y.; Chambers, L. R.; Bobkov, A. A.; Arakawa, N. K.; Matyszewski, M.; Corbett, K. D.
10.1101/2024.11.21.623966 — biochemistry — Posted on 2024-11-25
764 Engineering de novo binder CAR-T cell therapies with generative AI
Mergen, M.; Abele, D.; Koleci, N.; Schmahl Fernandez, A.; Sugden, M.; Holzleitner, N.; Carr, A.; Rieger, L.; Leone, V.; Reichert, M.; Laugwitz, K.-L.; Bassermann, F.; Busch, D. H.; Grunewald, J.; Schmidts, A.
10.1101/2024.11.25.625151 — bioengineering — Posted on 2024-11-25
770 Comparative analysis of iPSC-derived human kidney organoid and tubuloid models
Nunez Nescolarde, A.; Santos, L. L.; Kong, L.; Ekinci, E.; Moore, P.; Dimitriadis, E.; Nikolic-Paterson, D.; Combes, A. N.
10.1101/2024.11.24.625103 — molecular biology — Posted on 2024-11-25
771 Cell-specific oxidative metabolism of the renal cortex
Feola, K.; Venable, A. H.; Broomfield, T.; Llamas, C. B.; Mishra, P.; Huen, S.
10.1101/2024.11.24.622516 — molecular biology — Posted on 2024-11-25
773 Temperature, but not plant cultivar, influence the efficacy of insecticidal dsRNA in Colorado potato beetle
Darrington, M.; Solocinski, J.; Zhou, S.; Lecheta, M. C.; Palli, S. R.; Chen, Y. H.; Teets, N. M.
10.1101/2024.11.25.625268 — molecular biology — Posted on 2024-11-25
775 A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis
Majumdar, S.; Manjari, S. R.; Gamper, H. B.; Hou, Y.-M.; Banavali, N. K.; Ojha, A. K.; Agrawal, R. K.
10.1101/2024.11.25.625233 — microbiology — Posted on 2024-11-25
776 Secretory leukocyte protease inhibitor influences periarticular joint inflammation in B. burgdorferi-infected mice
Yu, Q.; Tang, X.; Hart, T.; Homer, R.; Belperron, A. A.; Bockenstedt, L.; Ring, A.; Nakamura, A.; Fikrig, E.
10.1101/2024.11.24.625079 — microbiology — Posted on 2024-11-25
777 Saccharibacteria deploy two distinct Type IV pili, driving episymbiosis, host competition, and twitching motility
Grossman, A. S.; Lei, L.; Botting, J. M.; Liu, J.; Nahar, N.; Souza, J. G. S.; Liu, J.; McLean, J. S.; He, X.; Bor, B.
10.1101/2024.11.25.624915 — microbiology — Posted on 2024-11-25
778 Glutaminolysis promotes the function of follicular helper T cells in lupus-prone mice
Choi, S. C.; Ge, Y.; Joshi, M. V.; Jimenez, D.; Padilla, L.; LaPlante, C.; Rathmell, J. C.; Mohamadzadeh, M.; Morel, L.
10.1101/2024.11.25.625088 — immunology — Posted on 2024-11-25
779 CRISPRi Screen Uncovers lncRNA Regulators of Human Monocyte Growth
Flores-Arena, C.; Malekos, E.; Covarrubias, S.; Sudek, L.; Montano, C.; Dempsey, V.; Hyunh, V.; Katzman, S.; Carpenter, S.
10.1101/2024.11.25.624758 — immunology — Posted on 2024-11-25
781 Ultra-high-throughput screening of antimicrobial combination therapies using a two-stage transparent machine learning model
Reuter, M. M.; Lev, K. L.; Albo, J.; Singh Arora, H.; Liu, N.; Tan, S.; Shay, M. R.; Sarkar, D.; Robida, A.; Sherman, D. H.; Richardson, R. J.; Cira, N. J.; Chandrasekaran, S.
10.1101/2024.11.25.625231 — systems biology — Posted on 2024-11-25
782 A Versatile Anti-CRISPR Platform for Opto- and Chemogenetic Control of CRISPR-Cas9 and Cas12 across a Wide Range of Orthologs
Brenker, L.; Aschenbrenner, S.; Bubeck, F.; Staykov, K.; Gebhardt, C.; Wolf, B.; Jendrusch, M.; Kroell, A.-S.; Mathony, J.; Niopek, D.
10.1101/2024.11.25.625186 — synthetic biology — Posted on 2024-11-25
786 Structure and mechanism of the RalGAP tumor suppressor complex
Rasche, R.; Klink, B. U.; Apken, L. H.; Michalke, E.; Chen, M.; Oeckinghaus, A.; Gatsogiannis, C.; Kuemmel, D.
10.1101/2024.11.25.625123 — biochemistry — Posted on 2024-11-25
787 Structural ubiquitin contributes to K48 linkage-specificity of the HECT ligase Tom1
Warner, K.; Hunkeler, M.; Baek, K.; Schmoker, A.; Burman, S. S. R.; Overwijn, D.; Jin, C.; Donovan, K. A.; Fischer, E. S.
10.1101/2024.11.25.625210 — biochemistry — Posted on 2024-11-25
790 Non-viral derivation of induced pluripotent stem cells from the canine umbilical cord
Yamazaki, A.; Shiozawa, S.; Koushige, Y.; Kondo, H.; Shibuya, H.; Edamura, K.
10.1101/2024.11.23.625030 — cell biology — Posted on 2024-11-25
791 Rigosertib reverses hypertrophic cardiomyopathy in RAF1-associated Noonan syndrome
Legler, L.; Xu, B.; Keshavarz Shirazi, T.; Kurzum, S.; Marchetti, K.; Kessinger, C. W.; Vredenburg, I.; Sun, Y.; Dinenno, F. A.; Bohler, D.; Aleman, A.; Rodriguez, N. A.; Ng, S.; Gao, S.; Wang, A.; Suarez-Farinas, M.; Lin, H.-M.; Das, T.; Ocorr, K.; Cagan, R. L.; Gelb, B. D.; Kontaridis, M. I.
10.1101/2024.11.25.623865 — molecular biology — Posted on 2024-11-25
792 HsbA represses stationary phase biofilm formation in Pseudomonas putida
Pulido Sanchez, M.; Moreno-Beltran, E.; Lopez-Sanchez, A.; Govantes, F.
10.1101/2024.11.25.625174 — microbiology — Posted on 2024-11-25
795 Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir
Briganti, L.; Annamalai, A. S.; Bester, S. M.; Wei, G.; Andino-Moncada, J. R.; Singh, S. P.; Kleinpeter, A.; Tripathi, M.; Nguyen, B.; Radhakrishnan, R.; Singh, P. K.; Greenwood, J.; Schope, L. I.; Haney, R.; Huang, S.-W.; Freed, E. O.; Engelman, A. N.; Francis, A.; Kvaratskhelia, M.
10.1101/2024.11.25.625199 — microbiology — Posted on 2024-11-25
801 Integration of hunger and hormonal state gates infant-directed aggression
Cao, M.; Ammari, R.; Chen, M. X.; Wai, P.; Sahni, A.; Liang, S.; Legrave, N.; MacRae, J. I.; Strom, M.; Kohl, J.
10.1101/2024.11.25.625278 — neuroscience — Posted on 2024-11-25
802 Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use
Barekat, K.; Ricciotti, E.; Ghosh, S.; Herrmann, C.; Keat, K.; Assenmacher, C.-A.; Tanes, C.; Wilson, N.; Sengupta, A.; Das, U. S.; Ritchie, M.; Bittinger, K.; Weljie, A.; Cadwell, K.; Bushman, F.; Wu, G.; FitzGerald, G. A.
10.1101/2024.11.22.624882 — pharmacology and toxicology — Posted on 2024-11-25
803 Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma
Purzner, J.; Brown, A. S.; Purzner, T.; Ellis, L.; Broski, S.; Litzenburger, U.; Andrews, K.; Sharma, A.; Wang, X.; Taylor, M. D.; Cho, Y.-J.; Fuller, M. T.; Scott, M. P.
10.1101/2024.11.21.624171 — cancer biology — Posted on 2024-11-25
809 Impacts of urbanization on the health of American Robins (Turdus migratorus) in Chicagoland
Riccardi, A.; Douglass, K. R.; Jackson, V. S.; Dehnert, G. K.; Herbst, H.; Grewe, F.; Walker, M.; Magle, S.; Murray, M. H.; Adams, H.; Brook, C. E.; Cornelius Ruhs, E.
10.1101/2024.11.24.625046 — ecology — Posted on 2024-11-25
811 The glycosyltransferase POGLUT1 regulates muscle stem cell development and maintenance in mice
Cho, S.; Servian-Morilla, E.; Garrido, V. N.; Rodriguez-Gonzalez, B.; Yuan, Y.; Cano, R.; Rambhiya, A. A.; Darabi, R.; Haltiwanger, R. S.; Paradas, C.; Jafar-Nejad, H.
10.1101/2024.11.25.625261 — developmental biology — Posted on 2024-11-25
812 CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency and cell death
Chammas, P.; Xie, S. Q.; Sepulveda-Rincon, L. P.; Leeke, B. J.; Dore, M. H.; Dormann, D.; Wagner, R. T.; McManus, M. T.; Karimi, M. M.; Young, G.; Percharde, M.
10.1101/2024.11.25.625195 — developmental biology — Posted on 2024-11-25
815 Fast Photostable Expansion Microscopy Using QDots andDeconvolution
Gunawardhana, L.; Moree, W.; Guo, J.; Artur, C.; Womack, T.; Mayerich, D.
10.1101/2024.11.25.625167 — neuroscience — Posted on 2024-11-25
819 A versatile mouse model to advance human microglia transplantation research in neurodegenerative diseases
De Strooper, B.; Lutgarde, S.; Sierksma, A.; Pasciuto, E.; Geric, I.; Nair, A.; Muriana, A. M.; Snellinx, A.
10.1101/2024.11.25.624854 — neuroscience — Posted on 2024-11-25
821 Parp1 deletion rescues cerebellar hypotrophy in xrcc1 mutant zebrafish
Semenova, S. A.; Nammi, D.; Garrett, G. A.; Margolin, G.; Sinclair, J. L.; Maroofian, R.; Caldecott, K. W.; Burgess, H. A.
10.1101/2024.11.25.625242 — neuroscience — Posted on 2024-11-25
822 Intranasal dantrolene nanoparticles inhibit inflammatory pyroptosis in 5XFAD mice brains
Bhuiyan, P.; Zhang, W.; Chae, R.; Kim, K.; St. Louis, L.; Wang, Y.; Liang, G. L.; Wei, H.
10.1101/2024.11.25.625293 — neuroscience — Posted on 2024-11-25
823 Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles
Saferin, N.; Haseeb, I.; Taha, A.; Beecroft, S.; Pillai, S.; Neifer, A. E.; Lakkuru, R.; Kistler, B. P.; Nawor, C. N.; Malik, I.; Hasan, D.; Carlson, J. A.; Zade, K. K.; Shah, R.; Gautam, S.; Vergis, J.; Neifer, K. L.; Johnson, Z. V.; Gustison, M. L.; Hall, F. S.; Burkett, J. P.
10.1101/2024.11.25.625285 — neuroscience — Posted on 2024-11-25
826 Cacao genome sequence reveals insights into the flavonoid biosynthesis
Marin Recinos, M. F.; Winnier, S.; Lagerhausen, K.; Ajayi, B.; Wolff, K.; Friedhoff, R.; Dassow, C. M.; Choudhary, N.; Pucker, B.
10.1101/2024.11.23.624982 — plant biology — Posted on 2024-11-25
827 Oxidative Injury to Lung Mitochondrial DNA is a Key Contributorfor the Development of Chemical Lung Injury
Dubey, S.; Yu, Z.; Stephens, E. M.; Lazrak, A.; Ahmad, I.; Aggarwal, S.; Andrabi, S.; Hossain, M. I.; Jilling, T.; Fernadez, S. R.; Bartels, J. L.; Lapi, S. E.; Mobley, J.; Pastukh, V. M.; Gillespie, M.; Matalon, S.
10.1101/2024.11.22.624949 — physiology — Posted on 2024-11-25
828 An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer
Shimada, K.; Michaud, D. E.; Cui, Y. X.; Zheng, K.; Goldberg, J.; Ju, Z.; Schnitt, S. J.; Pastorello, R.; Kania, L. D.; Hoffer, J.; Muhlich, J. L.; Hyun, N.; Krueger, R.; Gottlieb, A.; Nelson, A.; Wanderley, C. W.; Antonellis, G.; McAllister, S. S.; Tolaney, S. M.; Waks, A. G.; Jeselsohn, R.; Sorger, P. K.; Agudo, J.; Mittendorf, E. A.; Guerriero, J. L.
10.1101/2024.11.23.619172 — cancer biology — Posted on 2024-11-25
829 Molecular mechanism of Na+/H+ antiporting in NhaA
Xie, T.; He, J.; Sun, S.; Chen, Y.; Huang, J.; Huang, Y.
10.1101/2024.11.23.624977 — biophysics — Posted on 2024-11-25
832 High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages
Szyszka, T. N.; Siddiquee, R.; Loustau, A.; Adamson, L.; Rennie, C.; Huang, T.; Young, R.; Care, A.; Lau, Y. H.
10.1101/2024.11.24.625105 — biochemistry — Posted on 2024-11-25
833 Old age variably impacts chimpanzee engagement and efficiency in stone tool use
Howard-Spink, E.; Matsuzawa, T.; Carvalho, S.; Hobaiter, C.; Almeida-Warren, K.; Gruber, T.; Biro, D.
10.1101/2024.11.25.625128 — animal behavior and cognition — Posted on 2024-11-25
835 A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice.
Dougherty, J. D.; Maloney, S. E.; McCullough, K. B.; Chaturvedi, S. M.; Selmanovic, D.; Chase, R.; Chen, J.; Wu, D.; Granadillo, J. L.; Kroll, K. L.
10.1101/2024.11.25.625294 — animal behavior and cognition — Posted on 2024-11-25
837 Sumatran orangutan mothers differ in the extent and trajectory of their expression of maternal behaviour
Revathe, T.; Mundry, R.; Utami-Atmoko, S. S.; Umaira Aprilla, T.; A. van Noordwijk, M.; Froehlich, M.; Buerkner, P.-C.; Schuppli, C.
10.1101/2024.11.25.625129 — animal behavior and cognition — Posted on 2024-11-25
838 A novel framework for assessing the robustness of genomic animal models applied to a wild marine fish
Thia, J. A.; Aguirre, J. D.; Hereward, J.; Evans, J.; Liggins, L.; Riginos, C.; McGuigan, K.
10.1101/2024.11.25.625127 — genomics — Posted on 2024-11-25
842 Molecular patterns of evolutionary changes throughout the whole nervous system of multiple nematode species
Toker, I. A.; Ripoll-Sanchez, L.; Geiger, L. T.; Saini, K. S.; Beets, I.; Vertes, P. E.; Schafer, W. R.; Ben-David, E.; Hobert, O.
10.1101/2024.11.23.624988 — evolutionary biology — Posted on 2024-11-25
843 Diverse patterns of intra-host genetic diversity in chronically infected SARS-CoV-2 patients
Rutsinsky, N.; Ben Zvi, A.; Fabian, I.; Segev, S. T.; Jacobi, B.; Harari, S.; Meijers, S.; Paran, Y.; Stern, A.
10.1101/2024.11.23.624482 — evolutionary biology — Posted on 2024-11-25
848 Tertiary lymphoid structure as a therapeutic target of Crohns disease: modulation by TNFα blockade
Nagase, Y.; Okano, S.; Furukawa, A.; Kanazawa, T.; Yamamoto, K.; Yamamoto, K.; Ohashi, K.; Yamana, T.; Nojiri, S.; Suzuki, Y.; Kanai, A.; Yao, T.; Abe, K.; Ohteki, T.; Kodama, M.
10.1101/2024.11.23.625032 — immunology — Posted on 2024-11-25
849 Cells transit through a quiescent-like state to convert to neurons at high rates
Beitz, A. M.; Teves, J.; Oakes, C. G.; Johnstone, C. P.; Wang, N. B.; Brickman, J. M.; Galloway, K. E.
10.1101/2024.11.22.624928 — systems biology — Posted on 2024-11-25
851 Comparative transcriptomics of Lathyrus sativus reveals accession-specific resistance responses against Erysiphe pisi
Marques, R. M.; Fernandes, T.; Barros, P. M.; Leitäo, S. T.; Rubiales, D.; Vaz Patto, M. C.; Santos, C.
10.1101/2024.11.23.624375 — plant biology — Posted on 2024-11-25
852 Quantitative MRI Measurements Capture Pancreatic Cancer and Stroma Reactions to New KRAS Inhibitor
Gupta, M.; Choi, H.; Kemp, S.; Furth, E. E.; Pickup, S.; Clendenin, C.; Orlen, M.; Rosen, M.; Liu, F.; Cao, Q.; Stanger, B.; Zhou, R.
10.1101/2024.11.22.624844 — cancer biology — Posted on 2024-11-25
855 Ascitic fluid protects against ferroptosis and enables the peritoneal spread of ovarian cancer
Setayeshpour, Y.; Chen, S.-Y.; Dayanidhi, D. L.; Lee, Y.; Federico, C.; Aristizabal-Henao, J. J.; Wu, J.; Lin, C.-C.; Mestre, A.; Kiebish, M. A.; Berchuck, A.; Hsu, D. S.; Huang, Z.; Murphy, S. K.; Chi, J.-T. A.
10.1101/2024.11.23.624998 — cancer biology — Posted on 2024-11-25
856 Tau Aggregation is Altered by Mutations in its Projection Domain
Mason-Chalmers, K.; Sachdeva, A.; Kolk, G.; Touchon, J. C.; Donhauser, Z. J.
10.1101/2024.11.22.624898 — biophysics — Posted on 2024-11-25
857 ON-OFF nanopores for optical control of transmembrane ionic communication
Wang, X.; Kerckhoffs, A.; Riexinger, J.; Cornall, M.; Langton, M. J.; Bayley, H.; Qing, Y.
10.1101/2024.11.23.624940 — biophysics — Posted on 2024-11-25
861 Anatomical Region-Specific Transcriptomic Signatures and the Role of Epithelial Cells in Pterygium Inflammation: A Multi-Omics Analysis
Song, C.; Myung, S.; Cho, H.; Kim, T. G.; Chun, S.; Seo, M.; Yu, H.; Kim, S.; Kim, Y.-A.; Kim, J.; Shin, J.; Kang, J.; Lee, Y.; Kang, M. S.; Kim, M. S.
10.1101/2024.11.25.625095 — bioinformatics — Posted on 2024-11-25
862 CNV-Profile Regression: A New Approach for Copy Number Variant Association Analysis in Whole Genome Sequencing Data
Si, Y.; Lu, W.; Holloway, S. T.; Wang, H.; Tucci, A. A.; Brucker, A.; Cheng, Y.; Wang, L.-S.; Schellenberg, G. D.; Lee, W.-P.; Tzeng, J.-Y.
10.1101/2024.11.23.624994 — bioinformatics — Posted on 2024-11-25
864 Rabbit Heart Bioartificial Tissue: Perfusion Decellularization and Characterization
Seitzhaparova, B.; Kadyr, S.; Timur, L.; Mirasbek, B.; Zhakypbekova, A.; Lesbekov, T.; Erisken, C.
10.1101/2024.11.22.624857 — bioengineering — Posted on 2024-11-25
866 Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine
Hernandez, G.; Osinski, A.; Majumdar, A.; Eitson, J. L.; Antczak, M.; Pawlowski, K.; Niederstrasser, H.; Servage, K. A.; Posner, B.; Schoggins, J. W.; Ready, J. A.; Tagliabracci, V. S.
10.1101/2024.11.22.624893 — biochemistry — Posted on 2024-11-25
868 Sex-specific DNA methylation differences in Amyotrophic lateral sclerosis
Grant, O.; Iacoangeli, A.; Zwamborn, R.; van Rheenen, W.; Byrne, R. P.; van Eijk, K. R.; Kenna, K.; Van Vugt, J.; Cooper-Knock, J.; Kenna, B.; Vural, A.; Topp, S.; Smith, B.; Dobson, R.; van Es, M.; Gotkine, M.; Corcia, P.; de Carvalho, M.; Panades, M.; Mora, J.; Mill, J.; Garton, F.; McRae, A.; Wray, N.; Shaw, P.; Landers, J.; Glass, J.; Shaw, C.; Basak, N.; Hardiman, O.; Van Damme, P.; McLaughlin, R.; van den Berg, L.; Veldink, J.; Al Chalabi, A.; Al Kheifat, A.
10.1101/2024.11.22.624866 — genomics — Posted on 2024-11-25
871 Chromosome-scale genome assembly and linkage map for Silene uniflora reveal the recombination landscape in a rapidly evolving plant species
Osborne, O. G.; Wood, D. P.; Dobreva, M. P.; Dunning, L. T.; Tucker, R.; Coates, S. E. R.; Pellicer, J.; Holmberg, J.; Algar, A. C.; Bocedi, G.; Gubry-Rangin, C.; Herrera-Alsina, L.; Juliandi, B.; Lancaster, L.; Touzet, P.; Travis, J. M.; Papadopulos, A.
10.1101/2024.11.25.625183 — evolutionary biology — Posted on 2024-11-25
873 Predicting missing links in food webs using stacked models and species traits
Van Kleunen, L. B.; Dee, L. E.; Wootton, K. L.; Massol, F.; Clauset, A.
10.1101/2024.11.22.624890 — ecology — Posted on 2024-11-25
879 Residual flexibility in the topologically constrained multivalent complex between the GKAP scaffold and LC8 hub proteins
Nagy-Kanta, E.; Kalman, Z. E.; Tossavainen, H.; Juhasz, T.; Farkas, F.; Hegedus, J.; Keresztes, M.; Beke-Somfai, T.; Gaspari, Z.; Permi, P.; Peterfia, B.
10.1101/2024.11.25.624264 — molecular biology — Posted on 2024-11-25
880 The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus
Rosendal, E.; Bisikalo, K.; Willekens, S. M. A.; Lindgren, M.; Holoubek, J.; Svoboda, P.; Lappalainen, A.; Konighofer, E.; Mirgorodskaya, E.; Norden, R.; Morini, F.; Rosenbaum, W.; Ruzek, D.; Ahlgren, U.; Anastasina, M.; Merits, A.; Butcher, S. J.; Nilsson, E.; Overby, A. K.
10.1101/2024.10.16.618642 — microbiology — Posted on 2024-11-25
882 RetS senses neurotransmitter norepinephrine and adrenergic agents to regulate Pseudomonas aeruginosa virulence
Zhou, Y.; Ren, A.; Wang, C.; Zhou, T.; Deng, J.; Huang, Y.; Cui, R.; Huang, W.; Feng, Y.; Zheng, W.; Liang, H.; Yang, L.
10.1101/2024.11.24.625011 — microbiology — Posted on 2024-11-25
884 Novel Immunological Markers of Intestinal Impairment Indicative of HIV-1 Status and/or Subclinical Atherosclerosis
Moreira Gabriel, E.; Dias, J.; Caballero, R. E.; Wiche salinas, T. R.; Nayrac, M.; Filali-Mouhim, A.; Chartrand-Lefebvre, C.; Routy, J.-P.; Durand, M.; El-Far, M.; Tremblay, C. L.; Ancuta, P.
10.1101/2024.11.22.624885 — immunology — Posted on 2024-11-25
885 Dysregulated airway epithelial antiviral immunity in Down Syndrome impairs type III IFN response and amplifies airway inflammation during RSV infection.
Chorvinsky, E.; Bhattacharya, S.; Bera, B. S.; Welham, A. L.; Hussain Ismat, K.; Lawlor, C. M.; Preciado, D.; Gomez Villalobos, J.; Morizono, H.; Pillai, D.; Gutierrez, M. J.; Jaiswal, J.; Nino, G.
10.1101/2024.11.22.624921 — immunology — Posted on 2024-11-25
886 Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping
Wang, K.; Nie, Y.; Maguire, C.; Syphurs, C.; Sheen, H.; Karoly, M.; Lapp, L.; Gygi, J. P.; Jayavelu, N. D.; Patel, R. K.; Hoch, A.; IMPACC Network, ; Corry, D.; Kheradmand, F.; McComsey, G. A.; Fernandez-Sesma, A.; Simon, V.; Metcalf, J. P.; Agudelo Higuita, N. I.; Messer, W. B.; David, M. M.; Nadeau, K. C.; Kraft, M.; Bime, C.; Schaenman, J.; Erle, D.; Calfee, C. S.; Atkinson, M. A.; Brackenridge, S. C.; Hafler, D. A.; Shaw, A. C.; Rahman, A.; Hough, C. L.; Geng, L. N.; Ozonoff, A.; Haddad, E. K.; Reed, E. F.; Bakel, H. v.; Kim-Schulze, S. H.; Krammer, F.; Wilson, M.; Eckalbar, W.; Bosinger,
10.1101/2024.11.22.624784 — immunology — Posted on 2024-11-25
889 Respiratory pauses highlight sleep architecture in mice
Casali, G.; Miermon, C.; Terral, G.; Ravassard, P.; Dolique, T.; Harrell, E.; Lesburgueres, E.; Jarriault, D.; Gambino, F.; Chenouard, N.; Roux, L.
10.1101/2024.03.27.586921 — neuroscience — Posted on 2024-11-25
892 Ustilago maydis disrupts carbohydrate signaling networks to induce hypertrophy in host cells
Lee, Y. J.; Stolze, S. C.; Saraidis, G.; Ebert, M. K.; Nakagami, H.; Doehlemann, G.
10.1101/2024.11.22.624849 — plant biology — Posted on 2024-11-25
893 Key Regulatory Elements of the TGFbeta-LRRC15 Axis Predict Disease Progression and Immunotherapy Resistance Across Cancer Types
Storey, C. M.; Cheng, M.; Altai, M.; Park, J. E.; Tran, J.; Lueong, S. S.; Thorek, D. L.; Mao, L.; Zedan, W.; Yuen, C.; Ridley, A.; Trajkovic-Arsic, M.; Herrmann, K.; Subudhi, S. K.; Siddiqui, B. A.; Lueckerath, K.; Siveke, J.; Damoiseaux, R.; Yang, X.; Ulmert, D.
10.1101/2024.11.22.624939 — pharmacology and toxicology — Posted on 2024-11-25
895 Fluorescence based live cell imaging identifies exon 14 skipped hepatocyte growth factor receptor (MET) degraders
Mallareddy, J. R.; Yang, L.; Lin, W.-H.; Feathers, R.; Ayers-Ringler, J.; Tolosa, E.; Kizhake, A.; Kizhake, S.; Kubica, S.; Boghean, L.; Alvarez, S.; Naldrett, M. J.; Singh, S.; Rana, S.; Zahid, M.; Schaefer-Klein, J.; Roden, A.; Kosari, F.; Anastasiadis, P. Z.; Borad, M. J.; Natarajan, A.; Mansfield, A. S.
10.1101/2024.11.22.624922 — cancer biology — Posted on 2024-11-25
896 Towards robust machine olfaction: debiasing GC-MS data enhances prostate cancer diagnosis from urine volatiles
Rotteveel, A.; Lee, W.-Y.; Kountouri, Z.; Stefanou, N.; Kivell, H.; Gluck, C.; Zhang, S.; Mershin, A.
10.1101/2024.11.19.624273 — cancer biology — Posted on 2024-11-25
898 Sequence-Dependent Liquid Crystalline Ordering of Gapped DNA
Kodikara, S.; Gleeson, J.; Jakli, A.; Sprunt, S.; Balci, H.
10.1101/2024.11.22.624933 — biophysics — Posted on 2024-11-25
900 Variations in kinase and effector signaling logic in a bacterial two component signaling network
Swingle, D.; Epstein, L.; Aymon, R.; Isiorho, E. A.; Abzalimov, R. R.; Favaro, D. C.; Gardner, K. H.
10.1101/2024.11.04.621962 — biochemistry — Posted on 2024-11-25
904 Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons
Jones, A. G.; Schaal, G.; Boye, A.; Creemers, M.; Derolez, V.; Desroy, N.; Fiandrino, A.; Mouton, T. L.; Simier, M.; Smith, N.; Ouisse, V.
10.1101/2022.08.18.504439 — ecology — Posted on 2024-11-25
905 Partitioning changes in ecosystem productivity by effects of species interactions in biodiversity experiments
Tao, J.; Nock, C.; Searle, E. B.; Huang, s.; Man, R.; Yang, H.; Freschet, G.; Violle, C.; Zheng, J.
10.1101/2024.03.30.587418 — ecology — Posted on 2024-11-25
906 Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance
Zurawska, G.; Sas, Z.; Jonczy, A.; Mahadeva, R.; Slusarczyk, P.; Chwalek, M.; Seehofer, D.; Damm, G.; Kulecka, M.; Rumienczyk, I.; Moulin, M.; Jastrzebski, K.; Mikula, M.; Etzerodt, A.; Serwa, R.; Miaczynska, M.; Rygiel, T. P.; Mleczko-Sanecka, K.
10.1101/2023.11.14.566925 — cell biology — Posted on 2024-11-25
908 Anti-phase clustering of regulatory factors shapes gene bursting
Li, B.; Wong, Y. Y.; Flores-Rodriguez, N.; Davidson, T.; Graus, M. S.; Smialkovska, V.; Ohishi, H.; Feldmann, A.; Ochiai, H.; Francois, M.
10.1101/2024.09.10.612363 — molecular biology — Posted on 2024-11-25
911 Structure of the turnip yellows virus particles. How is the readthrough domain exposed on the capsid surface?
Lai-Kee-Him, J.; Trapani, S.; Boissinot, S.; Reinbold, C.; Fallet, C.; Ancelin, A.; Lecorre, F.; Hoh, F.; Ziegler-Graff, V.; Brault, V.; Bron, P.
10.1101/2024.10.14.617924 — microbiology — Posted on 2024-11-25
912 Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency
Leithner, A.; Staufer, O.; Mitra, T.; Liberta, F.; Valvo, S.; Kutuzov, M.; Dada, H.; Spaeth, J.; Zhou, S.; Schiele, F.; Reindl, S.; Nar, H.; Hoerer, S.; Crames, M.; Comeau, S.; Young, D.; Low, S.; Jenkins, E.; Davis, S. J.; Klenerman, D.; Nixon, A.; Pefaur, N.; Wyatt, D.; Dushek, O.; Kasturirangan, S.; Dustin, M. L.
10.1101/2022.06.15.496334 — immunology — Posted on 2024-11-25
913 Diverse priming outcomes under conditions of very rare precursor B cells
Madden, P. J.; Marina-Zarate, E.; Rodrigues, K. A.; Steichen, J. M.; Shil, M.; Ni, K.; Michaels, K. K.; Maiorino, L.; Upadhyay, A. A.; Saha, S.; Pradhan, A.; Kalyuzhiny, O.; Liguori, A.; Lopez, P. G.; Phung, I.; Phelps, N.; Georgeson, E.; Alavi, N.; Kubitz, M.; Lu, D.; Eskandarzadeh, S.; Metz, A.; Rodriguez, O. L.; Shields, K.; Schultze, S.; Smith, M. L.; Healy, B. S.; Lim, D.; Lewis, V. R.; Ben-Akiva, E.; Pinney, W.; Gregory, J.; Xiao, S.; Carnathan, D. G.; Kasturi, S. P.; Watson, C. T.; Bosinger, S. E.; Silvestri, G.; Schief, W. R.; Irvine, D. J.; Crotty, S.
10.1101/2024.11.21.624746 — immunology — Posted on 2024-11-25
915 Is mild ADHD beneficial? Brain criticality peaks at intermediate ADHD symptom scores across the population
Haque, H.; Hirvonen, J.; Wang, S. H.; Simola, J.; Morales-Munoz, I.; Cowley, B. U.; Palva, J. M.; Palva, S.
10.1101/2022.12.14.519751 — neuroscience — Posted on 2024-11-25
917 Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory
Yamawaki, N.; Login, H.; Feld-Jakobsen, S. O.; Molnar, B. M.; Kirkegaard, M. Z.; Moltesen, M.; Okrasa, A.; Radulovic, J.; Tanimura, A.
10.1101/2024.03.17.585387 — neuroscience — Posted on 2024-11-25
918 Cytokinin acts as a systemic signal coordinating reproductive effort in Arabidopsis
Volkava, D.; Bukovcakova, S. V.; Mikulkova, P.; Pecinkova, J.; Skalak, J.; Hejatko, J.; Riha, K.
10.1101/2024.07.09.602718 — plant biology — Posted on 2024-11-25
919 Callose deposition at plasmodesmata suggests a role in viral movement restriction in transgenic tobacco plants during recovery from Tobacco etch virus infection
Vargas-Mejia, P.; Olguin-Lamas, A.; Fernandez-Valverde, S. L.; Flores Garcia, C. M.; Lund, G.; Vielle-Calzada, J. P.; Silva-Rosales, L.
10.1101/2022.11.08.515744 — plant biology — Posted on 2024-11-25
920 Aromatase in adipose tissue exerts an osteoprotective function in male mice via phosphate regulation
Ikedo, A.; Yamashita, M.; Hoshino, M.; Okuno, Y.; Koike, M.; Uga, M.; Tanifuji, K.; Segawa, H.; Fukumoto, S.; Imai, Y.
10.1101/2024.06.24.600344 — physiology — Posted on 2024-11-25
921 Lysosomal signalling pathways influence heart rhythm, and regulate atrial function
Capel, R. A.; Akerman, E.; Rog-Zielinska, E.; Winbo, A.; Aston, D.; Mu-u-min, R. B. A.; Read, M. J.; Bose, S. J.; Swietach, P.; Wang, J.; Corbett, A. D.; Koschinski, A.; Falter, F.; Calamaio, S.; Melgari, D.; Prevostini, R.; Rivolta, I.; Ayagama, T.; Jenkin, I.; Simon, J. N.; Fakuade, F. E.; Pronto, J.; Sharma, P.; Song, Q.; Booth, M. J.; Platt, F. M.; Lei, M.; Hester, S.; Fischer, R.; Voigt, N.; Schotten, U.; Verheule, S.; Galione, A.; Keller, M.; Bracher, F.; Zaccolo, M.; Terrar, D. A.; Burton, R. A. B.
10.1101/2024.06.10.597905 — physiology — Posted on 2024-11-25
922 Non-lytic replicating viral delivery of an IL15 superagonist enhances antitumor immunity and extends survival in glioblastoma
Haddad, A. F.; Saha, A.; Spatz, J.; Collins, S.; Lovalvo, I.; Gill, S.; Montoya, M. L.; Shukla, P.; Hong, J.; Wang, E.; Chuntova, P.; Lad, M.; Osorio, R.; Chen, J.-S.; Jain, S.; Chalif, E.; Kasahara, N.; Aghi, M. K.
10.1101/2024.10.14.618095 — cancer biology — Posted on 2024-11-25
924 bamSliceR: a Bioconductor package for rapid, cross-cohort variant analysis
Huang, Y. P.; Harmon, L. M.; Gardner, E.; Ma, X.; Harsh, J.; Xue, Z.; Wen, H.; Ramos, M.; Davis, S. R.; Triche, T. J.
10.1101/2023.09.15.558026 — bioinformatics — Posted on 2024-11-25
928 Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms
Duca, F.; Bissacco, D.; Crugnola, L.; Faitini, C.; Domanin, M.; Migliavacca, F.; Trimarchi, S.; Vergara, C.
10.1101/2024.11.22.624794 — bioengineering — Posted on 2024-11-25
929 Chemical mate choice copying in Drosophila melanogaster
Mitchell, B.; Abbott, A.; Brown, A.; Skinner, L.; Umarova, E.; Kohlmeier, P.
10.1101/2024.06.23.600307 — animal behavior and cognition — Posted on 2024-11-25
931 Antibiotic treatment and microbiome depletion slow cnidarian regeneration
Da-Anoy, J.; Toyama, K. S.; Jasnos, O.; Wong, A.; Gilmore, T. D.; Davies, S. W.
10.1101/2024.11.24.625057 — developmental biology — Posted on 2024-11-25
932 The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy
POPLI, P.; Oestreich, A. K.; MAURYA, V. K.; ROWEN, M. N.; Masand, R.; Holtzman, M.; Zhang, Y.; P Lydon, J.; Shizuo Akira, P.; Moley, K.; Kommagnani, R.
10.1101/2024.03.19.585812 — developmental biology — Posted on 2024-11-25
933 Human CCR4-NOT globally regulates gene expression and is a novel silencer of retrotransposon activation
Kulkarni, S.; Morrissey, A.; Sebastian, A.; Giardine, B.; Smith, C.; Akinniyi, O. T.; Keller, C. A.; Arnaoutov, A.; Albert, I.; Mahony, S.; Reese, J. C.
10.1101/2024.09.10.612038 — molecular biology — Posted on 2024-11-25
935 Unraveling the Power of NAP-CNB's Machine Learning-enhanced Tumor Neoantigen Prediction
Mendez-Perez, A.; Acosta-Moreno, A. M.; Wert-Carvajal, C.; Ballesteros-Cuartero, P.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Alemany, R.; Sorzano, C. O. S.; Munoz-Barrutia, A.; Veiga, E.
10.1101/2023.11.22.568042 — immunology — Posted on 2024-11-25
936 A comprehensive chemotyping and gonadal regulation of seven kisspeptinergic neuronal populations in the mouse brain
Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez-Gonzalez, R.; Camacho-Arroyo, I. S.; Millar, R. P.; Eiden, L. E.; Zhang, L.
10.1101/2024.07.23.604881 — neuroscience — Posted on 2024-11-25
938 Discovery of a novel Trichuris species, T. incognita, with low sensitivity to albendazole-ivermectin treatment in Cote d'Ivoire patients, identified through fecal DNA metabarcoding
Venkatesan, A.; Chen, R.; Bär, M. A.; Schneeberger, P.; Reimer, B.; Hürlimann, E.; Coulibaly, J. T.; Ali, S. M.; Sayasone, S.; Soghigian, J.; Keiser, J.; Gilleard, J. S.
10.1101/2024.07.04.602123 — genomics — Posted on 2024-11-25
939 The ELF3-BBX24/BBX25-PIF4 module controls thermosensory growth in Arabidopsis
Malakar, B. C.; Singh, S.; Garhwal, V.; Chandramohan, R.; Upadhyaya, G.; Gangappa, S. N.
10.1101/2024.02.14.580362 — plant biology — Posted on 2024-11-25
941 WITHDRAWN: Effect of inactivated conditioned media from DENV-2-infected endothelial cells on epithelial cell healing: live cell imaging analysis.
Hincapie, V.; Cardona-Gomez, J. C.; Gallego-Gomez, J. C.; Villarreal-Julio, R. G.; Blandon, J.; Ordonez, B. E.; Perez, G. A.; Cuartas-Lopez, A. M.
10.1101/2024.10.11.617825 — microbiology — Posted on 2024-11-25
943 WITHDRAWN: Unveiling the Crucial Role of Pro-inflammatory Macrophages in the Immune Network Imbalance of the maternal-fetal interface with Preeclampsia
Fei, H.; Lu, X.; Shi, Z.; Liu, X.; Yang, C.; Zhu, X.; Lin, Y.; Jiang, Z.; Wang, J.; Huang, D.; Liu, L.; Zhang, S.; Jiang, L.
10.1101/2024.06.05.597577 — immunology — Posted on 2024-11-25
944 Dopamine alters motor learning performance in the presence and absence of feedback
Leow, L.-A.; Tan, A. H.-R.; Carroll, T. J.; Adam, R. J.; Dux, P. E.; Filmer, H. L.
10.1101/2024.11.23.625034 — neuroscience — Posted on 2024-11-25
947 Implication of S-1 biomarkers on aging and prognosis in elderly patients with lung cancer treated by adjuvant S-1 chemotherapy: Accompanying results of the Setouchi Lung Cancer Group Study 1201
Soh, J.; Yamamoto, H.; Okumura, N.; Suzuki, H.; Nakata, M.; Fujiwara, T.; Gemba, K.; Sano, I.; Fujinaga, T.; Kataoka, M.; Terasaki, Y.; Fujimoto, N.; Kataoka, K.; Kosaka, S.; Yamashita, M.; Inokawa, H.; Inoue, M.; Nakamura, H.; Yamashita, Y.; Takahashi, Y.; Torigoe, H.; Sato, H.; Tomida, S.; Hotta, K.; Yoshioka, H.; Morita, S.; Matsuo, K.; Sakamoto, J.; Date, H.; Toyooka, S.
10.1101/2024.11.23.625024 — pharmacology and toxicology — Posted on 2024-11-25
948 Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship
Thompson, G.; Hoyle, A.; Lewis, P. A.; Prada-Sanchez, M. E.; Swift, J.; Heesom, K.; Lowe, M.; Stephens, D. J.; Stevenson, N.
10.1101/2024.11.19.624265 — cell biology — Posted on 2024-11-25
949 Involvement of Hepatitis B Core-Related Antigen in Viral Genome Integration in Patients With Prior Hepatitis B Virus Infection
Saito, T.; Suzuki, R.; Rahman, A.; Mori, K.; Rajib, S. A.; Kobayashi, N.; Ichikawa, T.; Orimo, T.; Kakisaka, T.; Liang, L.; Nao, N.; Suzuki, S.; Tamura, T.; Satou, Y.; Taketomi, A.; Fukuhara, T.
10.1101/2024.11.21.624775 — microbiology — Posted on 2024-11-25
951 Replication stress marker phospho-RPA2 predicts response to platinum and PARP inhibitors in homologous recombination-proficient ovarian cancer
Schab, A.; Compadre, A.; Drexler, R.; Loeb, M.; Rodriguez, K.; Brill, J.; Harrington, S.; Sandoval, C.; Sanders, B.; Kuroki, L.; McCourt, C.; Hagemann, A. R.; Thaker, P.; Mutch, D.; Powell, M.; Serra, V.; Hagemann, I. S.; Walts, A. E.; Karlan, B. Y.; Orsulic, S.; Fuh, K.; Sun, L.; Verma, P.; Lomonosova, E.; Zhao, P.; Khabele, D.; Mullen, M. M.
10.1101/2024.11.21.624682 — cancer biology — Posted on 2024-11-25
952 NetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological networks
Paton, V.; Turei, D.; Ivanova, O.; Muller-Dott, S.; Rodriguez-Mier, P.; Venafra, V.; Perfetto, L.; Garrido-Rodriguez, M.; Saez-Rodriguez, J.
10.1101/2024.11.22.624823 — bioinformatics — Posted on 2024-11-25
957 Antibiotic treatment and microbiome depletion slow cnidarian regeneration
Da-Anoy, J.; Toyama, K. S.; Jasnos, O.; Wong, A.; Gilmore, T. D.; Davies, S. W.
10.1101/2024.11.24.625057 — developmental biology — Posted on 2024-11-24
960 A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin
Duan, T. Q.; Hagenauer, M. H.; Flandreau, E. I.; Bader, A.; Nguyen, D. M.; Maras, P. M.; Merscher Sobriera De Lima, R.; Gyles, T.; Mclain, C.; Meaney, M. J.; Nestler, E. J.; Watson, S. J.; Akil, H.
10.1101/2024.11.22.624315 — neuroscience — Posted on 2024-11-24
962 The Alzheimers Disease Risk Genes MS4A4A And MS4A6A Cooperate to Negatively Regulate Trem2 and Microglia states
Rosner, D.; Sun, J.; Yee, A.; Wagh, C.; Rychkova, A.; Cacae, R.; Buonfiglioli, A.; Alhawagri, M.; Kong, P.; Roell, M.; Ho, W.-H.; Gong, B.; Denton, H.; Muscanera, G.; Meese, T.; El Khatib, M.; Bermingham, D.; Kuhn, J.; Wang, X.; Gulbranson, D.; Rhinn, H.; Khan, Z.; Mitra, A.; Schwabe, T.; Srinivisan, K.; Tassi, I.; de Witte, L.; Mancuso, R.; Long, H.; Heutink, P.; Kenkare-Mitra, S.; Rosenthal, A.
10.1101/2024.11.23.625001 — neuroscience — Posted on 2024-11-24
963 Triple network dynamics and future alcohol consumption in adolescents
McIntyre, C. C.; Khodaei, M.; Lyday, R. G.; Weiner, J. L.; Laurienti, P. J.; Shappell, H. M.
10.1101/2024.11.22.624880 — neuroscience — Posted on 2024-11-24
966 Single CAR-Dual target: Intracranial Delivery of Anti-PD-L1 CAR T Cells Effectively Eradicates Glioma and Immunosuppressive Cells in the Tumor Microenvironment.
Ulloa-Navas, M. J.; Luo, Y.; Sanchez-Garavito, J. E.; Qie, Y.; Jones, V. K.; Brooks, M. M.; Aramburu-Berckemeyer, M. M.; Hundal, T.; Gadd, M. E.; Gomez-Palmero, C.; Brim, A. D.; Rivera-Valentin, R.; Basil, A. N.; Tutor-new, F. Q.; Hirdler, J. B.; Irani, S. R.; Dronca, R.; Kharfan-Dabaja, M.; Ren, Y.; Dong, H.; Qin, H.; Quinones-Hinojosa, A.
10.1101/2024.11.22.624897 — cancer biology — Posted on 2024-11-24
974 The conserved landscape of RNA modifications and transcript diversity across mammalian evolution
Rodriguez, G. S.; Akanksha, S.; Ravindran, A.; Oyelami, F.; Ip, C. K.; Gupta, P.; Villanueva, J.; King, H. E.; Grootveld, A.; Blackburn, J.; Gupta, I.; Viera, H. G. S.; Shirokikh, N.; Eyras, E.; Weatheritt, R. J.
10.1101/2024.11.24.624934 — genomics — Posted on 2024-11-24
979 Fisetin extends lifespan in a murine model of recessive dystrophic epidermolysis bullosa
Miller, W. C.; Strege, C. L.; Popp, C. M.; Tito, S. M. I.; Eide, C.; Ebens, C. L.; Riddle, M.; Lees, C.; Seelig, D.; Bui, K.; Yousefzadeh, M. J.; McGrath, J.; Tolar, J.
10.1101/2024.11.23.625023 — molecular biology — Posted on 2024-11-24
983 Yanomami skin microbiome complexity challenges prevailing concepts of healthy skin.
Durack, J.; Piceno, Y.; Vuong, H.; Fanelli, B.; Good, D. A.; Hasan, N. A.; Dadlani, M.; Weiss, L.; Oh, J.; Kostic, A. D.; Dawson, T. L.; Caballero-Arias, H.; Colwell, R. R.
10.1101/2024.11.23.625008 — microbiology — Posted on 2024-11-24
984 Diverse phage defence systems define West African South American pandemic Vibrio cholerae
Adams, D. W.; Jaskolska, M.; Lemopoulos, A.; Stutzmann, S.; Righi, L.; Bader, L.; Blokesch, M.
10.1101/2024.11.23.624991 — microbiology — Posted on 2024-11-24
991 Visual speech enhances auditory onset timing and envelope tracking through distinct mechanisms
Cao, C. Z.; Stacey, W. C.; Wasade, V. S.; Towle, V. L.; Tao, J. X.; Wu, S.; Issa, N. P.; Brang, D. J.
10.1101/2024.11.23.624953 — neuroscience — Posted on 2024-11-24
992 Global Neuron Shape Reasoning with Point Affinity Transformers
Troidl, J.; Knittel, J.; Li, W.; Zhan, F.; Pfister, H.; Turaga, S. C.
10.1101/2024.11.24.625067 — neuroscience — Posted on 2024-11-24
993 Advancing protein display on bacterial spores through an extensive survey of coat components
Chappell, T. C.; Nicks, T. B.; Cheng, J.-F.; Tarver, A.; Lee, J. A.; Kalia, A.; Nair, N. U.
10.1101/2024.11.22.624950 — synthetic biology — Posted on 2024-11-24
994 Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
Della Valle, S.; Orsi, E.; Creutzburg, S. C. A.; Jansen, L. F. M.; Pentari, E.-N.; Beisel, C. L.; Steel, H.; Nikel, P. I.; Staals, R. H. J.; Claassens, N. J.; van der Oost, J.; Huang, W. E.; Patinios, C.
10.1101/2024.11.24.625072 — bioengineering — Posted on 2024-11-24
997 A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection
Fitzmeyer, E. A.; Dutt, T. S.; Pinaud, S.; Graham, B.; Gallichotte, E. N.; Hill, J. L.; Campbell, C. L.; Ogg, H.; Howick, V. M.; Lawniczak, M. K.; Osborne Nishimura, E.; Merkling, S. H.; Henao-Tamayo, M.; Ebel, G. D.
10.1101/2024.07.23.603613 — microbiology — Posted on 2024-11-24
998 Complimentary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome
Lee, K.-H.; Stafford, A. M.; Pacheco-Vergara, M.; Cichewicz, K.; Canales, C. P.; Seban, N.; Corea, M.; Rahbarian, D.; Bonekamp, K. E.; Gillie, G. R.; Pacheco-Cruz, D.; Gill, A. M.; Hwang, H.-E.; Uhl, K.; Shinawi, M.; Li, X.; Obenaus, A.; Crandall, S. R.; Jeong, J.; Nord, A. S.; Kim, C.-H.; Vogt, D.
10.1101/2024.05.26.595966 — neuroscience — Posted on 2024-11-24
1002 Newly Sequenced Genomes Reveal Patterns of Gene Family Expansion in select Dragonflies (Odonata: Anisoptera)
Tolman, E. R.; Beatty, C. D.; Frandsen, P. B.; Bush, R. J.; Burchim, O. R.; Driever, E. S.; Harding, K. M.; Jordan, D.; Kohli, M. K.; Park, J.; Park, S.; Reyes, K.; Rosario, M.; Ryu, J. L.; Wade, V.; Ware, J. L.; Suvorov, A.
10.1101/2023.12.11.569651 — evolutionary biology — Posted on 2024-11-24
1005 MLL4 regulates postnatal palate growth and midpalatal suture development
Lee, J.-M.; Jung, H.; de Paula Machado Pasqua, B.; Park, Y.; Tang, Q.; Jeon, S.; Lee, S.-K.; Lee, J. W.; Kwon, H.-J. E.
10.1101/2024.07.16.603832 — developmental biology — Posted on 2024-11-24
1006 eIF3 engages with 3'-UTR termini of highly translated mRNAs
Mestre-Fos, S.; Ferguson, L.; Trinidad, M. I.; Ingolia, N.; Cate, J. H. D.
10.1101/2023.11.11.566681 — molecular biology — Posted on 2024-11-24
1007 Nanocarrier Drug Release and Blood-Brain Barrier Penetration at Post-Stroke Microthrombi Monitored by Real-Time Förster Resonance Energy Transfer-Based Detection System (FedEcs)
Khalin, I.; Adarsh, N.; Schifferer, M.; Wehn, A.; Boide-Trujillo, V. J.; Mamrak, U.; Shrouder, J. J.; Misgeld, T. J.; Filser, S.; Klymchenko, A. S.; Plesnila, N.
10.1101/2024.02.28.582471 — neuroscience — Posted on 2024-11-24
1011 AI-readiness for Biomedical Data: Bridge2AI Recommendations
Clark, T.; Caufield, H.; Parker, J. A.; Al Manir, S.; Amorim, E.; Eddy, J.; Gim, N.; Gow, B.; Goar, W.; Haendel, M.; Hansen, J. N.; Harris, N.; Hermjakob, H.; McWeeney, S. K.; Nebeker, C.; Nikolov, M.; Shaffer, J.; Sheffield, N.; Sheynkman, G.; Stevenson, J.; Mungall, C.; Chen, J. Y.; Wagner, A.; Kong, S. W.; Ghosh, S. S.; Patel, B.; Williams, A.; Munoz-Torres, M. C.
10.1101/2024.10.23.619844 — bioinformatics — Posted on 2024-11-24
1014 Inositol-Requiring Enzyme 1 Pathway and Autophagy Drive Sequential Response of Endothelial Cells to Febrile Range Hyperthermia
Vorbe, J.; Massey, F.; Morales, O.; Rocher, C.; Brikci, N.; Le Borgne, M.; Caligiuri, G.; Nicoletti, A.; Franck, G.; Illiano, S.
10.1101/2024.11.22.624904 — cell biology — Posted on 2024-11-24
1018 CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
Li, E.; Benitez, C.; Boggess, S. C.; Koontz, M.; Rose, I. V. L.; Martinez, D.; Draeger, N.; Teter, O. M.; Samelson, A. J.; Pierce, N.; Ullian, E. M.; Kampmann, M.
10.1101/2023.04.26.538498 — neuroscience — Posted on 2024-11-24
1019 Post-Transcriptional Modular Synthetic Receptors
Zhang, X.; Mille Fragoso, L. S.; Kaseniit, K. E.; Lee, A. P.; Zhang, M.; Call, C. C.; Hu, Y.; Xie, Y.; Gao, X. J.
10.1101/2024.05.03.592453 — synthetic biology — Posted on 2024-11-24
1020 Fibrous Network Nature of Plant Cell Walls Enables Tunable Mechanics for Development
Chen, S.; Burda, I.; Jani, P.; Pendrak, B.; Silberstein, M. N.; Roeder, A. H. K.
10.1101/2024.10.09.617478 — plant biology — Posted on 2024-11-24
1021 Mapping enhancer-gene regulatory interactions from single-cell data
Sheth, M. U.; Qiu, W.-L.; Ma, X. R.; Gschwind, A. R.; Jagoda, E.; Tan, A. S.; Einarsson, H.; Gorissen, B. L.; Dubocanin, D.; McGinnis, C. S.; Amgalan, D.; Satpathy, A. T.; Jones, T. R.; Steinmetz, L. M.; Kundaje, A.; Ustun, B.; Engreitz, J. M.; Andersson, R.
10.1101/2024.11.23.624931 — genetics — Posted on 2024-11-24
1023 Laminin β4 is required for the development of human peripheral sensory neurons
Saito-Diaz, K.; Saini, T.; Patel, A. J.; James, C.; Thomas, K. S.; Knight, T. N.; Gogita, S. B.; Zeltner, N.
10.1101/2024.11.22.624899 — cell biology — Posted on 2024-11-24
1025 Host specificity of gastrointestinal parasites in free-ranging sloths from Costa Rica
Vanderheoven, E.; Florida, M.; Cliffe, R.; Guzman, J.; Notarnicola, J.; Kartzinel, T.
10.1101/2024.11.22.624753 — ecology — Posted on 2024-11-23
1026 Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele.
Reghuvaran, A. C.; Kumar, A.; Lin, Q.; Rajeevan, N.; Sun, Z.; Shi, H.; Barsotti, G.; Tanvir, E. M.; Pell, J. F.; Perincheri, S.; Wei, C.; Planoutene, M.; Eichmann, A.; Mas, V.; Zhang, W.; Das, B.; Cantley, L. G.; Xu, L.; He, J. C.; Menon, M.
10.1101/2024.11.22.624409 — systems biology — Posted on 2024-11-23
1027 Local High-Protein, Plant-Based Ready-to-Use Therapeutic Food Enhances Recovery from Malnutrition in Rats
Bechoff, A.; Akomo, P.; Muleya, M.; Tsaousis, A. D.; Nikolaou, C. K.; Utume, L.; Schneider, A.; Khalaf, M.; Reifen, R.; Monsonego-Ornan, E.
10.1101/2024.11.22.624820 — physiology — Posted on 2024-11-23
1028 Mechanical stresses govern myoblast fusion and myotube growth
Le Toquin, Y.; Dubey, S.; Ardaseva, A.; Balasubramaniam, L.; Delaune, E.; Morin, V.; Doostmohammadi, A.; Marcelle, C.; Ladoux, B.
10.1101/2024.11.22.624831 — biophysics — Posted on 2024-11-23
1030 TMVisDB: A Resource for Transmembrane Protein Annotations and 3D Visualizations
Olenyi, T.; Marquet, C.; Grekova, A.; Houri, L.; Heinzinger, M.; Dallago, C.; Rost, B.
10.1101/2024.11.22.624323 — bioinformatics — Posted on 2024-11-23
1031 Characterizing cytosine methylation of polymorphic human transposable element insertions using human pangenome resources
Zhuo, X.; Tomlinson, C.; Belter, E. A.; Kuntala, P. K.; Saintilnord, W. N.; Lindsay, T.; Macias, J.; Fulton, R. S.; Wang, T.
10.1101/2024.11.22.623804 — bioinformatics — Posted on 2024-11-23
1032 VIACOT: a web server for interactive visualization and comparison of cell lineage trees
Yang, J.; Li, Z.; Zhang, X.; Chen, F.; Wu, P.; Yang, W.; He, X.; Shan, Y.; Yang, J.-R.
10.1101/2024.11.22.624819 — bioinformatics — Posted on 2024-11-23
1034 Arginyltransferase1 drives a mitochondria-dependent program to induce cell death
Kumar, A.; O'Shea, C. R.; Yadav, V. K.; Kandasamy, G.; Moorthy, B. T.; Ambrose, E.; Mulati, A.; Fontanesi, F.; Zhang, F.
10.1101/2024.11.22.624728 — biochemistry — Posted on 2024-11-23
1037 Whole-genome sequencing of Hyphopichia burtonii from isolated yeast recovered from zebra dove droppings in Thailand
Ngasaman, R.; Indoang, S.; Chumtong, S.; Prachantasena, S.; Wiriyaprom, R.; Surachart, K.; Promwisedc, R.
10.1101/2024.11.22.624822 — molecular biology — Posted on 2024-11-23
1038 Maximizing immunopeptidomics-based bacterial epitope discovery by multiple search engines and rescoring
Willems, P.; Thery, F.; Van Moortel, L.; De Meyer, M.; Staes, A.; Gul, A.; Kovalchuke, L.; Declercq, A.; Devreese, R.; Bouwmeester, R.; Gabriels, R.; Martens, L.; Impens, F.
10.1101/2024.11.22.624860 — molecular biology — Posted on 2024-11-23
1039 SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes accumulation of HIF1alpha and phosphorylated tau
Kettunen, P.; ruuska, j.; Quirin, T.; Ojha, R.; Saber, S. H.; Shaker, M.; Morrison, S.; Wolvetang, E.; Joensuu, M. S.; Koistinaho, J.; Rolova, T.; Balistreri, G.
10.1101/2024.11.21.624622 — microbiology — Posted on 2024-11-23
1040 Chlamydia trachomatis genomes from rectal samples: description of new clade comprising ompA-genotype L4 from Argentina
Buttner, K. A.; Wegner, F.; Bregy, V.; Entrocassi, A. C.; Gallo Vaulet, M. L.; Lopez Aquino, D.; La Rosa, L.; Svidler Lopez, L.; Puolakkainen, M. H.; Hiltunen-Back, E.; Imkamp, F.; Egli, A.; Seth-Smith, H. M.; Rodriguez Fermepin, M.
10.1101/2024.11.23.624510 — microbiology — Posted on 2024-11-23
1042 Heat shock factor 2 positively regulates oncogenic herpesvirus gene expression by remodeling the chromatin landscape
Cutrone, L.; Djupenström, H.; Peltonen, J.; Martinez Klimova, E.; Corso, S.; Giordano, S.; Sistonen, L.; Gramolelli, S.
10.1101/2024.11.22.624798 — microbiology — Posted on 2024-11-23
1043 IFNγ-Expressing Myeloid Cells Localize within Lipoproteinosis during Drug-Associated Pulmonary Alveolar Proteinosis occurring in Systemic Juvenile Idiopathic Arthritis
Delmastro, A.; Liu, C. C.; Ding, X.-W.; Tan, S. Y.; Averbukh, I.; Bosse, M.; Keyes, T.; Sharma, S.; Deutsch, G.; Angelo, M.; Saper, V. E.; Mellins, E. D.; McCaffrey, E. F.
10.1101/2024.11.22.624756 — immunology — Posted on 2024-11-23
1044 In situ Membrane Protein Expression by Efficient Recruitment of mRNA to the Membranes of Synthetic Cells
Fu, H.; Ma, L.; Xu, C.; Li, J.; Sun, Y.; Tao, Y.; Wang, H.; Hu, S.; Fu, M.; Zheng, H.; Liu, C.; Ye, F.; Qiao, Y.; Li, M.; Lu, Y.
10.1101/2024.11.23.624830 — synthetic biology — Posted on 2024-11-23
1045 An epigenetic basis for sustained inflammatory epithelial progenitor cell states in Crohn's disease
Karakasheva, T. A.; Morral Martinez, C.; Zhou, Y.; Qiu, J.; Chen, X. E.; Soto, G. E.; Nettleford, S. K.; Hix, O. T.; Roach, D. M.; Laguerta, A. M.; Thadi, A.; Edwards, R. M.; Aleynick, D.; Weinbrom, S.; Borodyanskaya, E.; Pickering, O. H.; Fulton, M.; Chen, C.-H.; Peterson, B. V.; Hagen, E. B.; Yannuzzi, I. P.; Haider, Z.; Cramer, Z.; Conrad, M.; Li, N.; Bewtra, M.; Uzun, Y.; Tan, K.; Kelsen, J. R.; Minn, A. J.; Lengner, C. J.; Hamilton, K. E.
10.1101/2024.11.22.622113 — physiology — Posted on 2024-11-23
1046 ALS driven by mutant NEK1 aggregation is accelerated by Pml loss, but clinically reversed through pharmacologic induction of Pml-mediated degradation
Georgiadou, P.; Erkaya, B.; Kawakita, M.; Sahin, E.; Ozturk, H.; Tiryaki, F.; Yildiz, K.; Ozgenc, I.; Pekbilir, E.; Dogan, S. A.; Lallemand-Breitenbach, V.; Vargas, S.; Prochiantz, A. L.; Firat-Karalar, E. N.; de The, H.; Sahin, U.
10.1101/2024.11.23.622051 — pathology — Posted on 2024-11-23
1047 Versatile Stain Transfer in Histopathology Using a Unified Diffusion Framework
Yan, X.; Yuan, M.; Lu, Y.; Zhang, Y.; Chen, Z.; Bao, P.; Li, Z.; Dong, B.; Yang, L.; Zhang, L.; Zhou, F.
10.1101/2024.11.23.624680 — pathology — Posted on 2024-11-23
1048 LIET Model: Capturing the kinetics of RNA polymerase from loading to termination
Stanley, J. T.; Barone, G. E. F.; Townsend, H. A.; Sigauke, R. F.; Allen, M. A.; Dowell, R. D.
10.1101/2024.10.03.616401 — bioinformatics — Posted on 2024-11-23
1049 CNV-Finder: Streamlining Copy Number Variation Discovery
Kuznetsov, N.; Daida, K.; Makarious, M. B.; Al-Mubarak, B.; Atterling Brolin, K.; Malik, L.; Kouam, C.; Baker, B.; Ostrozovicova, M.; Andersh, K. M.; Kung, P.-J.; Mecheri, Y.; Tay, Y.-W.; Soundous Malek, B.; Al Tassan, N.; Teresa Perinan, M.; Hong, S.; Koretsky, M.; Sargeant, L.; Levine, K.; Blauwendraat, C.; Billingsley, K. J.; Bandres-Ciga, S.; Leonard, H. L.; Morris, H. R.; Singleton, A. B.; Nalls, M. A.; Vitale, D.; The Global Parkinson's Genetics Program,
10.1101/2024.11.22.624040 — bioinformatics — Posted on 2024-11-23
1051 New algorithms for unsupervised cell clusteringfrom scRNA-seq data
Robles, M.; Diaz-Riano, J. I.; Forigua, C.; Ojeda, S.; Guio, L.; Siaucho, P.; Guzman-Porras, J.; Garcia-Orjuela, D.; Naranjo, A.; Maradei, S.; Quiroz, A.; Duitama, J.
10.1101/2024.11.22.624768 — bioinformatics — Posted on 2024-11-23
1052 Reprogramming the genome of M13 bacteriophage for all-in-one personalized cancer vaccine
Huang, S.; He, Y.; Madow, A.; Peng, H.; Griffin, M.; Qi, J.; Huang, M.; Amoroso, H.; Abrashoff, R.; Heldman, N.; Belcher, A.
10.1101/2024.11.22.624916 — bioengineering — Posted on 2024-11-23
1053 UniversalEPI: Harnessing Attention Mechanisms to Decode Chromatin Interactions in Rare and Unexplored Cell Types
Grover, A.; Zhang, L.; Muser, T.; Häfliger, S.; Wang, M.; Theis, F. J.; Ibarra, I. L.; Krymova, E.; Boeva, V.
10.1101/2024.11.22.624813 — genomics — Posted on 2024-11-23
1054 The Rise of Polyploids During Environmental Catastrophes
Chen, H.; Almeida-Silva, F.; Logghe, G.; Bonte, D.; Van de Peer, Y.
10.1101/2024.11.22.624806 — evolutionary biology — Posted on 2024-11-23
1055 The challenge of sequencing Chlamydia trachomatis and other bacterial STI genomes directly from clinical swabs: the optimum solution
Buttner, K. A.; Bregy, V.; Wegner, F.; Purushothaman, S.; Imkamp, F.; Roloff Handschin, T.; Puolakkainen, M. H.; Hiltunen-Back, E.; Braun, D.; Kisakesen, I.; Schreiber, A.; Entrocassi, A. C.; Gallo Vaulet, M. L.; Lopez Aquino, D.; Svidler Lopez, L.; La Rosa, L.; Egli, A.; Rodriguez Fermepin, M.; Seth-Smith, H.
10.1101/2024.11.23.624631 — microbiology — Posted on 2024-11-23
1057 Unbiased data-driven analysis of five amyloid-beta peptides for biomarker investigations in familial Alzheimer's disease
Llorente-Saguer, I.; Gabriele, R.; Bradshaw, T.; Leckey, C. A.; Belder, C. R. S.; Chavez-Gutierrez, L.; de Silva, R.; Fox, N. C.; Wray, S.; Oxtoby, N. P.; Arber, C.
10.1101/2024.11.23.624811 — neuroscience — Posted on 2024-11-23
1058 Innervation density governs crosstalk of GPCR-based norepinephrine and dopamine sensors
Lopez, R. C.; Noble, N.; Ozcete, O. D.; Cai, X.; Handy, G. E.; Andersen, J. W.; Patriarchi, T.; Li, Y.; Kaeser, P. S.
10.1101/2024.11.23.624963 — neuroscience — Posted on 2024-11-23
1060 Optogenetic stimulation of a cortical biohybrid implant guides goal directed behavior
Brown, J.; Zappitelli, K. M.; Dawson, P. M.; Yoon, E.; Schiraga, S. A.; Rochford, A. E.; Eltaeb, M.; Rodriguez, A.; Kong, Y.; Hodak, M.; Mardinly, A. R.
10.1101/2024.11.22.624907 — neuroscience — Posted on 2024-11-23
1067 A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation
Drouault, J.; Palaffre, C.; Millet, E. J.; Rodriguez, J.; Martre, P.; Johnson, K.; Parent, B.; Welcker, C.; Wisser, R. J.
10.1101/2024.07.10.602692 — plant biology — Posted on 2024-11-23
1068 Multiple Myeloma associated DIS3 mutations drive AID-dependent IgH Translocations
Kulinski, T. M.; Gewartowska, O.; Mahe, M.; Kasztelan, K.; Durys, J.; Stroynowska-Czerwinska, A.; Jedynak-Slyvka, M.; Owczarek, E. P.; Chaudhury, D.; Nowotny, M.; Pekowska, A.; Seraphin, B.; Dziembowski, A.
10.1101/2023.07.27.550610 — molecular biology — Posted on 2024-11-23
1070 Improving Predictability, Test-Retest Reliability and Generalisability of Brain-Wide Associations for Cognitive Abilities via Multimodal Stacking
Tetereva, A.; Knodt, A.; Melzer, T.; van der Vliet, W.; Gibson, B.; Hariri, A.; Whitman, E. T.; Li, J.; Deng, J.; Ireland, D.; Ramrakha, S.; Pat, N.
10.1101/2024.05.03.589404 — neuroscience — Posted on 2024-11-23
1073 Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH)
Edwards, M. D.; Yin, Z.; Sueda, R.; Gubanova, A.; Xu, C. S.; Lakner, V.; Murchie, M.; Lee, C.-Y.; Ng, K.; Farrell, K.; Faraway, R.; Ganguly, S.; Jacobs, E.; Bintu, B.; Isogai, Y.
10.1101/2024.09.14.613026 — neuroscience — Posted on 2024-11-23
1074 Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression
Aboharb, F.; Davoudian, P. A.; Shao, L.-X.; Liao, C.; Rzepka, G. N.; Wojtasiewicz, C.; Indajang, J.; Dibbs, M.; Rondeau, J.; Sherwood, A. M.; Kaye, A. P.; Kwan, A. C.
10.1101/2024.05.23.590306 — neuroscience — Posted on 2024-11-23
1076 Polyacrylamide-based Antimicrobial Copolymers to Replace or Rescue Antibiotics
Williams, S. C.; Chosy, M. B.; Jons, C. K.; Dong, C.; Prossnitz, A. N.; Liu, X.; Lopez Hernandez, H.; Cegelski, L.; Appel, E.
10.1101/2024.09.13.612993 — bioengineering — Posted on 2024-11-23
1077 Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M nanoparticle vaccine induces neutralizing responses in nonhuman primates
Patel, N.; Rehman, A.; Trost, J. F.; Flores, R.; Longacre, Z.; Guebre-Xabier, M.; Zhou, H.; Zhou, B.; Jacobson, K.; Jiang, D.; Bai, X.; Khatoon, R.; Kort, T.; Norton, J.; Madhangi, M.; Hersey, M.; Greene, A. M.; Smith, G.
10.1101/2024.11.21.624712 — microbiology — Posted on 2024-11-23
1078 Origins of noise in both improving and degrading decision making
Shen, B.; Nguyen, D.; Wilson, J. M.; Glimcher, P. W.; Louie, K.
10.1101/2024.03.26.586597 — neuroscience — Posted on 2024-11-23
1081 PyEvoCell: An LLM- Augmented Single Cell Trajectory Analysis Dashboard
Mathur, S.; Beauvais, M.; Giribet, A.; Aragon Barrero, N.; Zhang, C.; Rahman, T.; Wang, S.; Huang, J.; Nouri, N.; Kurlovs, A.; Bar-Joseph, Z.; Passban, P.
10.1101/2024.11.21.624686 — bioinformatics — Posted on 2024-11-23
1090 Assessing changes in whole-brain structural connectivity in the unilateral 6-hydroxydopamine rat model of Parkinson's Disease using diffusion imaging and tractography
Moshchin, M.; Schultz, R. J.; Cheng, K. P.; Osting, S.; Koeper, J. C.; LaLuzerne, M.; Trevathan, J. K.; Brzeczkowski, A.; Luu, C. P.; Yu, J. P. J.; Betzel, R. F.; Lake, W. B.; Hurley, S. A.; Ludwig, K. A.; Suminski, A. J.
10.1101/2024.11.22.624742 — neuroscience — Posted on 2024-11-22
1093 Conformational plasticity across phylogenetic clusters of RND multidrug efflux pumps and its impact on substrate specificity
Lazarova, M.; Eicher, T.; Boernsen, C.; Zeng, H.; Athar, M.; Okada, U.; Yamashita, E.; Spannaus, I. M.; Borgosch, M.; Cha, H.-j.; Vargiu, A. V.; Murakami, S.; Diederichs, K.; Frangakis, A. S.; Pos, K. M.
10.1101/2024.11.22.624703 — biochemistry — Posted on 2024-11-22
1095 Linking Brain and Behavior States in Zebrafish Larvae Locomotion using Hidden Markov Models
Dommanget-Kott, M.; Fernandez-de-Cossio-Diaz, J.; Coraggioso, M.; Bormuth, V.; Monasson, R.; Debregeas, G.; Cocco, S.
10.1101/2024.11.22.624881 — animal behavior and cognition — Posted on 2024-11-22
1100 Buprenorphine Induces Human Fetal Membrane Sterile Inflammation
Lynn, T.; Kelleher, M. E.; Georges, H. M.; McCauley, E. M.; Logan, R.; Yonkers, K. A.; Abrahams, V. M.
10.1101/2024.11.22.624850 — immunology — Posted on 2024-11-22
1101 Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X
Mossa, A.; Dierdorff, L.; Lukin, J.; Park, Y.; Fiorenzani, C.; Akpinar, Z.; Garcia-Forn, M.; De Rubeis, S.
10.1101/2024.11.22.624865 — neuroscience — Posted on 2024-11-22
1102 Electrical synapse molecular diversity revealed by proximity-based proteomic discovery
Michel, J. C.; Martin, E. A.; Crow, W. E.; Kissinger, J. S.; Lukowicz-Bedford, R. M.; Horrocks, M.; Branon, T. C.; Ting, A. Y.; Miller, A. C.
10.1101/2024.11.22.624763 — neuroscience — Posted on 2024-11-22
1103 Visual and auditory object representations in ventral visual cortex after restoring sight in humans
Raczy, K.; Linke, M.; van den Hurk, J.; Heitmann, C.; Guerreiro, M. J. S.; Zhan, M.; Kekunnaya, R.; Goebel, R.; Roeder, B.
10.1101/2024.11.22.624459 — neuroscience — Posted on 2024-11-22
1106 Efficient pheromone navigation via antagonistic detectors
Wan, X.; Zhou, T.; Susoy, V.; Park, C. F.; Groaz, A.; Brady, J. F.; Samuel, A. D. T.; Sternberg, P. W.
10.1101/2024.11.22.624901 — neuroscience — Posted on 2024-11-22
1110 Uncovering genetic linkages in the rhizosphere contributing to adaptation
Williams, J. L.; Killian, E. Z.; Halpin-McCormick, A.; Kantar, M. B.; Sherman, J. D.; Ewing, P. M.; Eberly, J. O.; Lachowiec, J.
10.1101/2024.11.21.624704 — plant biology — Posted on 2024-11-22
1112 Depletion of all platelet integrins impacts hemostasis, thrombosis and tumor metastasis
Janus-Bell, E.; Liboni, C.; Yakusheva, A.; Mittelheisser, V.; Mouriaux, C.; Bourdon, C.; Bochler, L.; Hyenne, V.; Garcia-Leon, M.; Lefebvre, O.; GOETZ, J. G.; Mangin, P. H.
10.1101/2024.11.22.624871 — cancer biology — Posted on 2024-11-22
1114 Ion channel function of polycystin-2/polycystin-1 heteromer revealed by structure-guided mutagenesis
Staudner, T.; Khamseekaew, J.; Madej, M. G.; Geiges, L.; Azemi, B.; Ziegler, C.; Korbmacher, C.; Ilyaskin, A. V.
10.1101/2024.11.22.624889 — biophysics — Posted on 2024-11-22
1118 Cryo-EM Structure of AAA + ATPase Thorase Reveals Novel Helical Filament Formation
Dar, M. A.; Louder, R.; Cortes, M.; Chen, R.; Ma, Q.; Chakrabarti, M.; Umanah, G. K.; Dawson, T. M.; Dawson, V. L.
10.1101/2024.11.22.624887 — biochemistry — Posted on 2024-11-22
1119 14-3-3 binding maintains the Parkinson's associated kinase LRRK2 in an inactive state
Martinez Fiesco, J. A.; Li, N.; Alvarez de la Cruz, A.; Metcalfe, R. D.; Beilina, A.; Cookson, M. R.; Zhang, P.
10.1101/2024.11.22.624879 — biochemistry — Posted on 2024-11-22
1120 diaPASEF-Powered Chemoproteomics Enables Deep Kinome Interaction Profiling
Woods, K.; Rants'o, T. A.; Chan, A. M.; Sapre, T.; Mastin, G. E.; Maguire, K. M.; Ong, S.-E.; Golkowski, M.
10.1101/2024.11.22.624841 — biochemistry — Posted on 2024-11-22
1121 Corylus avellana non-specific lipid-transfer protein Cor a 8 is a moonlighting enzyme with a new lipase activity
Fissore, A.; Di Napoli, G.; De Sciscio, M. L.; Santoro, V.; Salladini, E.; Marengo, M.; Oliaro-Bosso, S.; Vanzetti, G.; Caratti, A.; Dal Piaz, F.; Piazza, F.; Manzoli, M.; Genova, G.; Barbiroli, A. G.; Iametti, S.; Fraternali, F.; Adinolfi, S.
10.1101/2024.11.22.624807 — biochemistry — Posted on 2024-11-22
1124 Telomere interactions and structural variants in ALT cells revealed with TelSPRITE
Wilson, D. G.; Clatterbuck Soper, S. F.; Pineda, M. A.; Walker, R. L.; Meltzer, P. S.
10.1101/2024.11.22.624895 — genomics — Posted on 2024-11-22
1128 Mapping the endosomal proximity proteome reveals Retromer as a hub for RAB GTPase regulation.
Anton-Plagaro, C.; Chen, K.-e.; Guo, Q.; Liu, M.; Evans, A. J.; Lewis, P. A.; Heesom, K. J.; Wilkinson, K.; Collins, B.; Cullen, P. J.
10.1101/2024.11.22.622898 — cell biology — Posted on 2024-11-22
1131 In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants
Bendall, E. E.; Dimcheff, D.; Papalambros, L.; Fitzsimmons, W. J.; Zhu, Y.; Schmitz, J. E.; Halasa, N.; Chappell, J. D.; Martin, E. T.; Biddle, J. E.; Smith-Jeffcoat, S. E.; Rolfes, M. A.; Mellis, A.; Talbot, H. K.; Grijalva, C. G.; Lauring, A. S.
10.1101/2024.11.21.624722 — microbiology — Posted on 2024-11-22
1134 Phage DisCo: targeted discovery of bacteriophages by co-culture
Rand, E. A.; Owen, S. V.; Quinones-Olvera, N.; Jean, K.; Hernandez-Perez, C.; Baym, M.
10.1101/2024.11.22.624878 — microbiology — Posted on 2024-11-22
1135 Poxviruses induce a nuclear environment in the cytoplasm to promote viral replication
Veratti, P.; Wyler, E.; Read, C.; Scherer, M.; Tan, J.; Walther, P.; Wider, S.; Weidl, D.; Full, F.
10.1101/2024.11.21.624458 — microbiology — Posted on 2024-11-22
1136 Targeted CRISPR Screens Reveal Genes Essential for Cryptosporidium Survival in the Host Intestine
Watson, L. C.; Sala, K. A.; Bernitz, N.; Baumgartel, L.; Pallett, M. A.; Marzook, N. B.; Straker, L. C.; Peng, D.; Collinson, L.; Sateriale, A.
10.1101/2024.11.22.624643 — microbiology — Posted on 2024-11-22
1138 Sex-dependent effects of a glutamine supplementation on metabolic disorders, intestinal barrier function and gut microbiota in mice with diet-induced obesity.
Lefebvre, C.; Tiffay, A.; Breemeersch, C.-E.; Dreux, V.; Bole-Feysot, C.; Guerin, C.; Breton, J.; Maximin, E.; Monnoye, M.; Dechelotte, P.; Douard, V.; Coiffier, M.; Goichon, A.
10.1101/2024.11.21.624683 — pathology — Posted on 2024-11-22
1139 SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis
Asrani, K.; Amaral, A.; Woo, J.; Abadchi, S. N.; Vidotto, T.; Feng, K.; Liu, H. B.; Kasbe, M.; Baba, M.; Oike, Y.; Outeda, P.; Watnick, T.; Rosenberg, A. Z.; Schmidt, L. S.; Linehan, M.; Argani, P.; Lotan, T. L.
10.1101/2024.11.21.624702 — cancer biology — Posted on 2024-11-22
1141 Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function
Bremer, A.; Lang, W. H.; Kempen, R. P.; Sweta, K.; Taylor, A. B.; Borgia, M. B.; Ansari, A. Z.; Mittag, T.
10.1101/2024.11.21.624739 — biophysics — Posted on 2024-11-22
1142 BioLLM: A Standardized Framework for Integrating and Benchmarking Single-Cell Foundation Models
Qiu, P.; Chen, Q. Q.; Qin, H.; Fang, S.; Zhang, Y.; Xia, T.; Cao, L.; Zhang, Y.; Fang, X.; Li, Y.; Hu, L.
10.1101/2024.11.22.624786 — bioinformatics — Posted on 2024-11-22
1143 Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in-vivo CAR-T therapy for inflamm-aging
Zhang, Z.; Ma, B.; Li, B.; Li, Z.; Gao, M.; Zhao, H.; Peng, R.; Hu, J.; Wang, Y.; You, W.; Gui, X.; Wang, R.; Hu, X.; Chen, B.; Zhang, Y.; Hao, Y.; Zhou, D.; Yang, Y.; Deng, M.; Miao, L.
10.1101/2024.11.21.624667 — bioengineering — Posted on 2024-11-22
1145 Phylogeographic patterns of Escherichia coli isolated from white-tailed deer, Odocoileus virginianus , during necropsy in a farmed deer surveillance program
Metrailer, M. C.; Cheng, A.-C.; Bluhm, A. P.; Jiranantasak, T.; Norris, M. H.; Surphlus, A.; Subrramanium, K.; Jeong, K. C.; Wisely, S. M.; Campos, J. M.; Blackburn, J. K.
10.1101/2024.11.21.624738 — genomics — Posted on 2024-11-22
1146 Genomes of two invasive Adelges species (hemlock woolly adelgid and pineapple gall adelgid) enable characterization of nicotinic acetylcholine receptors
Glendening, A. M.; Stephens, C.; Vuruputoor, V. S.; Stern, D. L.; Hogenhout, S. A.; Mathers, T. C.; Chaganti, T.; Pauloski, N.; Cernack, T. A.; Wegrzyn, J. L.; Fetter, K. C.
10.1101/2024.11.21.624573 — genomics — Posted on 2024-11-22
1147 Identifying genomic adaptation to local climate using a mechanistic evolutionary model
Goel, N.; Bossu, C. M.; Van Ee, J. J.; Zavaleta, E.; Ruegg, K. C.; Hooten, M. B.
10.1101/2024.11.21.624744 — genomics — Posted on 2024-11-22
1153 The Late-Stage Steps of Burkholderia cenocepacia Protein O-Linked Glycan Biosynthesis Are Conditionally Essential.
Jebeli, L.; McDaniels, T. A.; Ho, D. T. T.; Tahir, H.; Kai-Ming, N. L.; Mcgaw, M.; Karlic, K. I.; Lewis, J. M.; Scott, N. E.
10.1101/2024.11.21.624715 — microbiology — Posted on 2024-11-22
1154 Diverse priming outcomes under conditions of very rare precursor B cells
Madden, P. J.; Marina-Zarate, E.; Rodrigues, K. A.; Steichen, J. M.; Shil, M.; Ni, K.; Michaels, K. K.; Maiorino, L.; Upadhyay, A. A.; Sahi, S.; Pradhan, A.; Kalyuzhiny, O.; Liguori, A.; Lopez, P. G.; Phung, I.; Phelps, N.; Georgeson, E.; Alavi, N.; Kubitz, M.; Lu, D.; Eskandarzadeh, S.; Metz, A.; Rodriguez, O. L.; Shields, K.; Schultze, S.; Smith, M. L.; Healy, B. S.; Lim, D.; Lewis, V. R.; Ben-Akiva, E.; Pinney, W.; Gregory, J.; Xiao, S.; Carnathan, D. G.; Kasturi, S. P.; Watson, C. T.; Bosinger, S. E.; Silvestri, G.; Schief, W. R.; Irvine, D. J.; Crotty, S.
10.1101/2024.11.21.624746 — immunology — Posted on 2024-11-22
1155 Natural killer cell dysfunction drives keloid pathogenesis
Zhao, Y.; Wei, Q.; Zeng, R.; Wang, Y.; Yang, Y.; Wang, Y.
10.1101/2024.11.20.624588 — immunology — Posted on 2024-11-22
1156 M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits
Ochoa, S.; Rasquel-Oliveira, F. S.; McKinnon, B.; Haro, M.; Subramaniam, S.; Yu, P.; Coetzee, S.; Anglesio, M. S.; Wright, K. N.; Meyer, R.; Gargett, C. E.; Mortlock, S.; Montgomery, G. W.; Rogers, M. S.; Lawrenson, K.
10.1101/2024.11.21.624726 — immunology — Posted on 2024-11-22
1158 Dermatopontin-expressing fibroblasts mediate an essential skin macrophage niche
Vollmers, A. C.; Wu, S. Z.; Altieri, A.; McCartney, E. E.; Bender, H.; Lee, W. P.; Zhang, J.; Hu, C.; Uttarwar, S.; Vander Heiden, J. A.; Davidson, C.; Chung, Y.; Ortiz, W.; Long, M.; Asuncion, R.; Yang, Y. A.; Jiang, J.; Modrusan, Z.; Krishnamurty, A.; Fu, W.; Müller, S.; Buechler, M. B.; Turley, S.
10.1101/2024.11.21.624708 — immunology — Posted on 2024-11-22
1159 Conformational ensemble-based framework enables rapid development of Lassa virus vaccine candidates
Mishra, N.; Avillion, G.; Callaghan, S.; DiBiase, C.; Hurtado, J.; Liendo, N.; Burbach, S.; Messmer, T.; Briney, B.
10.1101/2024.11.21.624760 — immunology — Posted on 2024-11-22
1163 A high-quality phased genome assembly of stinging nettle, Urtica dioica ssp. dioica
Hirabayashi, K.; Dumigan, C. R.; Kucka, M.; Percy, D. M.; Guerriero, G.; Cronk, Q.; Deyholos, M. K.; Todesco, M.
10.1101/2024.11.21.624787 — plant biology — Posted on 2024-11-22
1165 The Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle
Ahn, A.; Kim, J. J.; Slusher, A. L.; Ying, J. Y.; Zhang, E. Y.; Ludlow, A. T.
10.1101/2024.11.21.624690 — physiology — Posted on 2024-11-22
1167 Metabolic Adaptations To Acute Glucose Uptake Inhibition Converge Upon Mitochondrial Respiration For Leukemia Cell Survival
Komza, M.; Khatun, J.; Gelles, J. D.; Trotta, A. P.; Abraham-Enachescu, I.; Henao, J.; Elsaadi, A.; Kotini, A. G.; Clementelli, C.; Arandela, J.; El Ghaity-Beckley, S.; Barua, A.; Chen, Y.; Marcellino, B. K.; Papapetrou, E. P.; Poyurovsky, M. V.; Chipuk, J. E.
10.1101/2024.11.20.624567 — cancer biology — Posted on 2024-11-22
1168 Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models
Bedia, J. S.; Huang, Y.-W.; Gonzalez, A. D.; Gonzalez, V. D.; Funingana, I.-G.; Rahil, Z.; Mike, A.; Lowar, A.; Vias, M.; Ashworth, A.; Brenton, J. D.; Fantl, W. J.
10.1101/2024.11.21.624591 — cancer biology — Posted on 2024-11-22
1169 Observing picomolar protein unfolding using resonance light scattering
Alvarez, A. B.; Arvesen, K. B.; Bjerring, P.; Hjuler, K. F.; Petersen, S. B.
10.1101/2024.11.20.624557 — biophysics — Posted on 2024-11-22
1174 Automatic Phenotyping Using Exhaustive Projection Pursuit
Moore, W. A.; Meehan, S. W.; Meehan, C.; Parks, D. R.; Walther, G.; Herzenberg, L. A.
10.1101/2024.11.20.624581 — bioinformatics — Posted on 2024-11-22
1176 An Open-Source Neurodynamic Model of the Bladder
Lister, E.; McConnell-Trevillion, A.; Jabbari, M.; Erfanian, A.; Nazarpour, K.
10.1101/2024.11.21.624716 — bioinformatics — Posted on 2024-11-22
1178 STEP: Deciphering Spatial Atlas at Single-Cell Level with Whole-Transcriptome Coverage
Hu, Z.; Zhu, Z.; Cai, L.; Zhan, Y.; Yan, X.; Chen, J.; Sun, B.; Du, S.; Jiang, S.; Wang, H.; Zhang, Y.
10.1101/2024.11.22.624797 — bioinformatics — Posted on 2024-11-22
1181 Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms
Duca, F.; Bissacco, D.; Crugnola, L.; Faitini, C.; Domanin, M.; Migliavacca, F.; Trimarchi, S.; Vergara, C.
10.1101/2024.11.22.624794 — bioengineering — Posted on 2024-11-22
1182 Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway
Yu, S.; Ding, J.; Wang, W.; Wang, J.; Zuo, P.; Yang, A.; Dai, Z.; Yin, Y.; Sun, J.; Liang, L.
10.1101/2024.11.21.624772 — biochemistry — Posted on 2024-11-22
1183 A quantitative framework for structural interpretation of DMS reactivity
Deenalattha, S.; Jurich, C. P.; Lange, B.; Armstrong, D.; Nein, K.; Yesselman, J. D.
10.1101/2024.11.21.624766 — biochemistry — Posted on 2024-11-22
1185 Molecular and genetic characterization of sex-linked orange coat color in the domestic cat
Kaelin, C. B.; McGowan, K. A.; Koroma, D. C.; Trotman, J.; David, V. A.; Menotti-Raymond, M.; Graff, E.; Schmidt-Kuentzel, A.; Oancea, E.; Barsh, G. S.
10.1101/2024.11.21.624608 — genetics — Posted on 2024-11-22
1191 Improving antibody-mediated protection against HSV infection by eliminating interactions with the viral Fc receptor gE/gI
Slein, M. D.; Backes, I. M.; Kelkar, N. S.; Garland, C. R.; Khanwalkar, U. S.; Sholukh, A. M.; Johnston, C. M.; Leib, D. A.; Ackerman, M. E.
10.1101/2024.11.20.624598 — immunology — Posted on 2024-11-22
1195 CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics
Raychaudhuri, K.; Rangu, R.; Ma, A.; Alvinez, N.; Tran, A. D.; Pallikkuth, S.; McIntire, K. M.; Garvey, J. A.; Yi, J.; Samelson, L. E.
10.1101/2024.06.27.601067 — immunology — Posted on 2024-11-22
1196 Whole-body simulation of realistic fruit fly locomotion with deep reinforcement learning
Vaxenburg, R.; Siwanowicz, I.; Merel, J.; Robie, A. A.; Morrow, C.; Novati, G.; Stefanidi, Z.; Both, G.-J.; Card, G. M.; Reiser, M. B.; Botvinick, M. M.; Branson, K. M.; Tassa, Y.; Turaga, S. C.
10.1101/2024.03.11.584515 — animal behavior and cognition — Posted on 2024-11-22
1198 Rapid ecological and evolutionary divergence during a poleward range expansion
Sheffer, M. M.; Schulze, B.; Zander, L.; Mouginot, P.; Naef, T.; Lalk, M.; Wurster, M.; Ahrend, C.; Kreyling, J.; Gillespie, R. G.; Hoff, K. J.; Prost, S.; Krehenwinkel, H.; Uhl, G.
10.1101/2021.11.04.467261 — ecology — Posted on 2024-11-22
1199 Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells
Wellington, R.; Cheng, X.; Campbell, C. A.; Trapnell, C.; Espin-Palazon, R.; Hadland, B.; Doulatov, S.
10.1101/2024.09.24.612755 — developmental biology — Posted on 2024-11-22
1202 Speech motor cortex enables BCI cursor control and click
Singer-Clark, T.; Hou, X.; Card, N. S.; Wairagkar, M.; Iacobacci, C.; Peracha, H.; Hochberg, L. R.; Stavisky, S. D.; Brandman, D. M.
10.1101/2024.11.12.623096 — neuroscience — Posted on 2024-11-22
1204 Characterizing the temporal dynamics and maturation of brain activity during sleep: an EEG microstate study in preterm and full-term infants.
Adibpour, P.; Nasser, H.; Pedoux, A.; Devisscher, L.; Elbaz, N.; Ghozland, C.; Hinnekens, E.; Neumane, S.; Kabdebon, C.; Lefebvre, A.; Kaminska, A.; Hertz-Pannier, L.; Heneau, A.; Sibony, O.; Alison, M.; Delanoe, C.; Delorme, R.; Barbu-Roth, M.; Biran, V.; Dubois, J.
10.1101/2024.03.19.585608 — neuroscience — Posted on 2024-11-22
1208 Modality-Specific and Amodal Language Processing by Single Neurons
Lakretz, Y.; Friedmann, N.; King, J.-R.; Mankin, E.; Rangel, A.; Tankus, A.; Dehaene, S.; Fried, I.
10.1101/2024.11.16.623907 — neuroscience — Posted on 2024-11-22
1209 Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease
Fleck, K.; Luria, V.; Garag, N.; Karger, A.; Hunter, T.; Marten, D.; Phu, W.; Nam, K.-M.; Sestan, N.; O'Donnell-Luria, A. H.; Erceg, J.
10.1101/2024.03.17.585403 — evolutionary biology — Posted on 2024-11-22
1210 Heme's relevance genuine? Re-visiting the roles of TANGO2 homologs including HRG-9 and HRG-10 in C. elegans
Sandkuhler, S. E.; Youngs, K.; Owlett, L.; Bandora, M.; Naaz, A.; Kim, E. S.; Wang, L.; Wojtovich, A. P.; Gupta, V. A.; Sacher, M.; Mackenzie, S. J.
10.1101/2023.11.29.569072 — cell biology — Posted on 2024-11-22
1211 KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe
Alharbi, R.; Keles, M.; Fernandes, N.; Maude, H.; Fellows, A.; Williams, R. D.; Chen, C.-N.; Lambie, N.; Matthews, N.; Al-Sahaf, M.; Guo, M.; Zhao, L.; Lawrie, A.; Whitsett, J. A.; Cebola, I.; Wojciak-Stothard, B.
10.1101/2024.07.08.602619 — cell biology — Posted on 2024-11-22
1212 Amyloplasts are necessary for full gravitropism in thallus of Marchantia polymorpha
Hashimoto-Sugimoto, M.; Norizuki, T.; Segami, S.; Ohta, Y.; Suetsugu, N.; Ueda, T.; Morita, M. T.
10.1101/2024.11.20.624610 — cell biology — Posted on 2024-11-22
1213 Common patterns of spatial selectivity in early visual cortex and face-selective brain regions
Morsi, A. Y.; Chow-Wing-Bom, H. T.; Schwarzkopf, D. S.; Goffaux, V.; Dekker, T. M.; Greenwood, J. A.
10.1101/2024.05.14.594166 — neuroscience — Posted on 2024-11-22
1214 Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons
Le Bail, R.; Lakaye, B.; Espuny Camacho, I.; Janke, C.; Magiera, M. M.; Engel, D.; Silva, C.; Nguyen, L.
10.1101/2024.11.08.622673 — neuroscience — Posted on 2024-11-22
1215 Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species
Kjer, M.; Andersson, M.; He, Y.; Pacureanu, A.; Daducci, A.; Pizzolato, M.; Salditt, T.; Robisch, A.-L.; Eckermann, M.; Töpperwien, M.; Dahl, A. B.; Elkjaer, M. L.; Illes, Z.; Ptito, M.; Andersen Dahl, V.; Dyrby, T. B.
10.1101/2023.10.16.562488 — neuroscience — Posted on 2024-11-22
1216 Dynamic prioritisation of sensory and motor contents in working memory
Echeverria-Altuna, I.; Boettcher, S. E. P.; van Ede, F.; Nobre, A. C.
10.1101/2024.11.12.623203 — neuroscience — Posted on 2024-11-22
1218 Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis
Jirouskova, M.; Harant, K.; Cejnar, P.; Ojha, S.; Korelova, K.; Sarnova, L.; Sticova, E.; Mayr, C. H.; Schiller, H. B.; Gregor, M.
10.1101/2024.03.26.586230 — pathology — Posted on 2024-11-22
1220 Color-barcoded Super-multiplex RNA FISH in Three-dimensional Tissues through Single-round Imaging
Chang, T.; Zhao, S.; Deng, K.; Liao, Z.; Tang, M.; Zhu, Y.; Han, W.; Yu, C.; Fan, W.; Jiang, M.; Wang, G.; Liu, D.; Peng, J.; Pang, Y.; Fei, P.; Wang, J.; Zheng, C.; Huang, Y.
10.1101/2024.06.29.601330 — bioengineering — Posted on 2024-11-22
1221 Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes
Baur, M.; Schulz, N. K. E.; Greune, L.; Langer, Z. M.; Eirich, J.; Finkemeier, I.; Peuss, R.; Dersch, P.; Kurtz, J.
10.1101/2024.11.21.624623 — evolutionary biology — Posted on 2024-11-22
1223 Studies in vitro e in vivo of Phage Therapy Medical Products (PTMPs) targeting clinical strains of Klebsiella pneumoniae belonging to the clone ST512
Bleriot, I.; Blasco, L.; Fernandez-Grela, P.; Fernandez-Garcia, L.; Arman, L.; Ibaguren-Quiles, C.; Ortiz-Cartagena, C.; Barrio-Pujante, A.; Pano Pardo, J. R.; Oteo-Iglesias, J.; Tomas, M.
10.1101/2024.11.20.624559 — microbiology — Posted on 2024-11-22
1224 Yeasts prefer daycares and molds prefer private homes
Kauserud, H.; Martin-Sanchez, P. M.; Estensmo, E. L.; Smebye Botnen, S.; Morgado, L.; Maurice, S.; Hoiland, K.; Skrede, I.
10.1101/2024.11.20.624568 — microbiology — Posted on 2024-11-22
1226 A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies
Balligand, T.; Carpenet, C.; Olive Palau, S.; Jaspers, T.; Suresh, P.; Liu, X.; Medhi, H.; Lee, Y. H.; Rashidian, M.; De Strooper, B.; Ploegh, H. L.; Dewilde, M.
10.1101/2024.11.20.624506 — immunology — Posted on 2024-11-22
1227 Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity
Franken, G.; Cuenca-Escalona, J.; Stehle, I. F.; van Reijmersdal, V.; Rodgers Furones, A.; Gokhale, R. R.; Classens, R.; diBlasio, S.; Dolen, Y.; van Spriel, A.; Querol Cano, L.
10.1101/2023.10.30.564706 — immunology — Posted on 2024-11-22
1228 Brain-Cognitive Gaps in relation to Dopamine and Health-related Factors: Insights from AI-Driven Functional Connectome Predictions
Esmaeili, M.; Bjorkeli, E. B.; Pedersen, R.; Falahati, F.; Johansson, J.; Nordin, K.; Karalija, N.; Bäckman, L.; Nyberg, L.; Salami, A.
10.1101/2024.11.19.624334 — neuroscience — Posted on 2024-11-22
1234 Cardiac electrical abnormalities in a mouse model of left ventricular non-compaction cardiomyopathy
de la Pompa, J. L.; Fernandes, V. S.; Caballero, R.; Siguero-Alvarez, M.; Papoutsi, T.; Gimeno-Blanes, J. R.; Delpon, E.
10.1101/2024.11.20.624427 — developmental biology — Posted on 2024-11-22
1235 A flexible high-precision photoacoustic retinal prosthesis
Leong, A.; Li, Y.; Ruikes, T. R.; Voillot, J.; Yuan, Y.; Chen, G.; Facon, A.; Chhuon, C.-A.; Joffrois, C.; Tessier, G.; Cornebois, M.; Degardin, J.; Louise, J.-D.; Cheng, J.-X.; Yang, C.; Moulet, H.; Picaud, S.
10.1101/2024.09.03.611068 — neuroscience — Posted on 2024-11-22
1238 Ancestry-specific gene expression in peripheral monocytes mediates risk of neurodegenerative disease
Wagen, A. Z.; Reynolds, R. H.; Nee Foo, J.; Fairbrother-Browne, A.; Gustavsson, E. K.; Gagliano-Turin, S. A.; Wood, N. W.; Blauwendraat, C. K.; Gandhi, S.; Ryten, M.
10.1101/2024.11.20.624489 — genetics — Posted on 2024-11-22
1239 Modeling Mountain Pine Beetle Abundance in Novel Hosts
Xie, X.; Brush, M.; Johnson, E.; Cullingham, C.; Duffy, J.; Lewis, M. A.
10.1101/2024.11.21.624504 — ecology — Posted on 2024-11-22
1240 Modelling the prebiotic origins of regulation & agency in evolving protocell ecologies
Shirt-Ediss, B.; Ferrero-Fernandez, A.; De Martino, D.; Bich, L.; Moreno, A.; Ruiz-Mirazo, K.
10.1101/2024.11.20.624505 — ecology — Posted on 2024-11-22
1243 Evaluation of protein intake and protein quality in New Zealand vegans
Soh, B. X. P.; Vignes, M.; Smith, N. W.; von Hurst, P. R.; McNabb, W. C.
10.1101/2024.11.20.624496 — physiology — Posted on 2024-11-22
1246 Lewy-MSA hybrid fold drives distinct neuronal a-synuclein pathology
Enomoto, M.; Martinez-Valbuena, I.; Forrest, S. L.; Xu, X.; Munhoz, R. P.; Li, J.; Rogaeva, E.; Lang, A. E.; Kovacs, G. G.
10.1101/2024.11.21.624748 — pathology — Posted on 2024-11-22
1248 NEMF inhibits proliferation and migration of ovarian cancer cells by blocking the PI3K/mTOR pathway
Wang, Q.; Zhu, Y.; Zhang, Y. l.; Chen, C. z.; Jing, F.; Yin, A. q.; Guo, S. q.; Liu, Y. h.
10.1101/2024.11.20.624445 — cancer biology — Posted on 2024-11-22
1251 Understanding the Dynamics of Biomass Deconstruction by the Cellulolytic Anaerobe C. thermocellum
Yarbrough, J.; Stich, D.; Hengge, N.; Xu, Q.; Chung, D.; Ziegler, S.; Huang, S.; Morais, S.; Mizrahi, I.; Bayer, E. A.; Bomble, Y.
10.1101/2024.11.19.624254 — microbiology — Posted on 2024-11-22
1253 Dysregulated Proteins in Plasma Distinguishing Syndromic from Non-syndromic Heritable Thoracic Aortic Disease
Seim, B. E.; Khan, Y.; Holt, M. F.; Ratajska, A.; Michelsen, A. E.; Mykelbust Ringseth, M.; Lundblad, R.; Halvorsen, B.; Krohg-Sorensen, K.; Nygard Osnes, L. T.; Aukrust, P.; Paus, B.; Kvitting, J.-P. E. E.; Ueland, T.
10.1101/2024.11.18.624213 — immunology — Posted on 2024-11-22
1255 Speech motor cortex enables BCI cursor control and click
Singer-Clark, T.; Hou, X.; Card, N. S.; Wairagkar, M.; Iacobacci, C.; Peracha, H.; Stavisky, S.; Brandman, D.
10.1101/2024.11.12.623096 — neuroscience — Posted on 2024-11-22
1257 R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease
Fisher, T.; Patel, M.; Deshmukh, S.; Shah, D.; Lu, C.; Newman, M.; Ye, J.; Fletcher, R.; Vanhove, G. F.; Tibbitts, J.; Li, Y.; Skill, N. J.; Yang, Z.; Liangpunsakul, S.; Baribault, H.
10.1101/2024.11.19.624277 — pathology — Posted on 2024-11-22
1262 A modular encapsulation system for precision delivery of proteins, nucleic acids and therapeutics
Luong, T. D.; Martel, N.; Rae, J.; Lo, H. P.; Lim, Y.-W.; Wu, Y.; McMahon, K.-A.; Fletcher, N.; Thurecht, K. J.; Johnston, A. P. R.; Ariotti, N.; Hall, T. E.; Parton, R. G.
10.1101/2024.08.22.607124 — bioengineering — Posted on 2024-11-22
1263 High δ15N values in Predynastic Egyptian archeological remains: A potential indicator for localised soil fertilisation practices in extreme conditions
Poulallion, E.; Perraud, A.; Besson, D.; Berthet, D.; Richardin, P.; Vincon-Laugier, A.; Fourel, F.; Flandrois, J.-P.; Maureille, B.; Lecuyer, C.
10.1101/2024.11.18.624066 — ecology — Posted on 2024-11-22
1267 CMTM6 maintains B cell intrinsic CD40 expression to regulate anti-tumor immunity
Long, Y.; Chen, R.; Chang, W.; Li, F.; Gu, L.; Sun, J.; Chen, J.; Gong, L.
10.1101/2024.03.05.583639 — immunology — Posted on 2024-11-22
1268 Early-Life Gut Inflammation Drives Sex-Dependent Shifts in the Microbiome-Endocrine-Brain Axis
Sullivan, O.; Sie, C.; Ng, K. M.; Cotton, S.; Rosete, C.; Hamden, J. E.; Singh, A. P.; Lee, K.; Choudhary, J.; Kim, J.; Yu, H.; Clayton, C.; Garcia, N. A. C.; Voznyuk, K.; Deng, B. D.; Plett, N.; Arora, S.; Ghezzi, H.; Huan, T.; Soma, K. K.; Yu, J.-P. J.; Tropini, C.; Ciernia, A. V.
10.1101/2024.05.23.595618 — neuroscience — Posted on 2024-11-22
1271 Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer
Yang, X.; Ma, X.; Zhao, T.; Croucher, D. R.; Nguyen, E. V.; Clark, K. C.; Hu, C.; Latham, S. L.; Bayly-Jones, C.; Nguyen, V. C. B.; Budnar, S.; Shin, S.; Nguyen, L. K.; Cotton, T. R.; Chueh, A. C.; Sian, T. C. L. K.; Stratton, M. M.; Ellisdon, A. M.; Daly, R. J.
10.1101/2024.02.14.580406 — cancer biology — Posted on 2024-11-22
1272 CelLink: integrating single-cell multi-omics data with weak feature linkage and imbalanced cell populations
Luo, X.; Huang, Y.; Tao, Y.; Feng, F.; Hopkirk, A.; Bate, T. S. R.; Saunders, D. C.; Orchard, P.; Robertson, C.; Shrestha, S.; Jean-Philippe, C.; Parker, S.; Brissova, M.; Liu, J.
10.1101/2024.11.08.622745 — bioinformatics — Posted on 2024-11-22
1278 Mechanisms of growth-dependent regulation of the Gin4 kinase
Diaz, F. M.; Godinez, D. S.; Solano, F.; Jasani, A.; Alcaide Gavilan, M.; Kellogg, D.
10.1101/2024.11.20.624605 — cell biology — Posted on 2024-11-21
1281 Inactive structures of the vasopressin V2 receptor reveal distinct antagonist binding modes for Tolvaptan and Mambaquaretin toxin
Fouillen, A.; Bous, J.; Couvineau, P.; Orcel, H.; Mary, C.; Pierre, T.; Mendre, C.; Gilles, N.; Schulte, G.; Granier, S.; Mouillac, B.
10.1101/2024.11.20.624478 — pharmacology and toxicology — Posted on 2024-11-21
1282 A single high-zinc activation enhancer can control two genes oriented head-to-head in C. elegans
Liu, H.; Earley, B.; Mendoza, A.; Hunt, P.; Teng, S.; Schneider, D. L.; Kornfeld, K.
10.1101/2024.11.19.624376 — genetics — Posted on 2024-11-21
1286 Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M nanoparticle vaccine induces neutralizing responses in nonhuman primates
Patel, N.; Rehman, A.; Frost, J. F.; Flores, R.; Longacre, Z.; Guebre-Xabier, M.; Zhou, H.; Zhou, B.; Jacobson, K.; Jiang, D.; Bai, X.; Khatoon, R.; Kort, T.; Norton, J.; Madhangi, M.; Hersey, M.; Greene, A. M.; Smith, G.
10.1101/2024.11.21.624712 — microbiology — Posted on 2024-11-21
1290 Oxytocin neurons in the paraventricular and supraoptic hypothalamic nuclei bidirectionally modulate food intake
Rea, J. J.; Liu, C. M.; Hayes, A. M. R.; Ohan, R.; Schwartz, G. M.; Bashaw, A. G.; Klug, M. E.; Decarie-Spain, L.; Park, Y.; Kao, A. E.; Grinevich, V.; Kanoski, S. E.
10.1101/2024.11.20.624599 — neuroscience — Posted on 2024-11-21
1293 Targeting eIF4G1-dependent translation in melanoma
Feng, Y.; Radaeva, M.; Amiri, M.; Deshpande, A.; Olson, S.; Jovanovic, P.; Amiri, M.; Pass, I.; Deng, Q.; Lazar, I.; Murad, R.; Molinolo, A.; Kim, H.; Sergienko, E.; Villaneuva, J.; Topisirovic, I.; Jackson, M.; Sonenberg, N.; Cherkasov, A.; Ronai, Z. A.
10.1101/2024.11.20.624566 — cancer biology — Posted on 2024-11-21
1294 Effective targeting of CD19 positive primary B-ALL cells using CAR-NK cells generated with mRNA-LNPs
Salehi-Shadkami, H.; Sedghi, M.; Tavoosi, S.; Alimohammadi, M.; Alimohammadi, R.; Barkhordar, M.; Mofayezi, A.; Modaresi, M. S.; Vaezi, M.; Dehghanizadeh, S.; Ahmadvand, M.; Khoddami, V.
10.1101/2024.11.21.624707 — cancer biology — Posted on 2024-11-21
1295 Reciprocal links between methionine metabolism, DNA repair and therapy resistance in glioblastoma
Korimerla, N.; Meghdadi, B.; Haq, I.; Wilder-Romans, K.; Xu, J.; Becker, N.; Zhu, Z.; Kalev, P.; Qi, N.; Evans, C.; Kachman, M.; Zhao, Z.; Lin, A.; Scott, A. J.; O'Brien, A.; Kothari, A.; Sajjakulnukit, P.; Zhang, L.; Palavalasa, S.; Peterson, E. R.; Hyer, M. L.; Marjon, K.; Sleger, T.; Morgan, M. A.; Lyssiotis, C. A.; Stone, E. M.; Ferris, S. P.; Lawrence, T. S.; Nagrath, D.; Zhou, W.; Wahl, D.
10.1101/2024.11.20.624542 — cancer biology — Posted on 2024-11-21
1302 Engineering of soluble bacteriorhodopsin
Nikolaev, A.; Orlov, Y.; Tsybrov, F.; Kuznetsova, E.; Shishkin, P.; Kuzmin, A.; Mikhailov, A.; Galochkina, Y. S.; Anuchina, A.; Chizhov, I.; Semenov, O.; Kapranov, I.; Borshchevskiy, V.; Remeeva, A.; Gushchin, I.
10.1101/2024.11.20.624543 — bioengineering — Posted on 2024-11-21
1306 The genome of a sea spider corroborates a shared Hox cluster motif in arthropods with reduced posterior tagma
Papadopoulos, N.; Kulkarni, S.; Baranyi, C.; Fromm, B.; Setton, E.; Sharma, P. P.; Wanninger, A.; Brenneis, G.
10.1101/2024.11.20.624475 — evolutionary biology — Posted on 2024-11-21
1307 Metabolic trade-offs in response to increased acetate metabolism in Escherichia coli
Pentz, J. T.; Koehler, S. I.; Middlebrook, E. A.; You Mak, K. T.; Hovde, B. T.; Hanschen, E. R.
10.1101/2024.11.20.624476 — evolutionary biology — Posted on 2024-11-21
1312 Description of two novel Corynebacterium species isolated from human nasal passages and skin
Popowitch, E. B.; Tran, T. H.; Fernandez Escapa, I.; Bhatt, E.; Sozat, A. K.; Ahmed, N.; Deming, C.; Roberts, A. Q.; NISC Comparative Sequencing Program, ; Segre, J. A.; Kong, H. H.; Conlan, S.; Lemon, K. P.; Kelly, M. S.
10.1101/2024.11.21.624533 — microbiology — Posted on 2024-11-21
1316 Dendritic cells accelerate CAR T cells in irradiated tumors through chimeric synapses
Navarre, S.; Ishibashi, M.; Nair, A.; Reyes-Torres, I.; Belabed, M.; Halasz, L.; Park, M. D.; Mattiuz, R.; Ounadjela, M.; Gunset, G.; Mansilla-Soto, J.; Feucht, J.; Cabriolu, A.; Le Berichel, J.; Eyquem, J.; Brown, B.; Merad, M.; Sadelain, M.; Ahmed, J.
10.1101/2024.11.19.624339 — immunology — Posted on 2024-11-21
1318 Soma-centered control of synaptic autophagy by Rab39-regulated anterograde trafficking of Atg9
Kilic, A.; Vandekerkhove, D.; Kuenen, S.; Swerts, J.; Munoz Pedrazo, E.; Calatayud, C.; Escamilla Ayala, A.; Corthout, N.; Hernandez Varas, P.; Plaisance, S.; Nachman, E.; Uytterhoeven, V.; Verstreken, P.
10.1101/2024.11.21.624639 — neuroscience — Posted on 2024-11-21
1321 Semantic integration demands modulate large-scale network interactions in the brain
Nieberlein, L.; Martin, S.; Williams, K. A.; Gussew, A.; Cyriaks, S. D.; Scheer, M.; Rampp, S.; Prell, J.; Hartwigsen, G.
10.1101/2024.11.20.624508 — neuroscience — Posted on 2024-11-21
1322 The human claustrum activates across multiple cognitive tasks
Huang, C. H. L.; Stewart, B. W.; Liu, C. Y.; Phylactou, P.; Mathur, B. N.; Seminowicz, D. A.
10.1101/2024.11.20.624607 — neuroscience — Posted on 2024-11-21
1324 Barley resistance and susceptibility to fungal cell entry involve the interplay of ROP signaling with phosphatidylinositol-monophosphates
Weiss, L. S.; Bartram, C.; Bradai, M.; Heilmann, M.; Mergner, J.; Kuster, B.; Hensel, G.; Kumlehn, J.; Engelhardt, S.; Heilmann, I.; Huckelhoven, R.
10.1101/2024.11.19.624325 — plant biology — Posted on 2024-11-21
1325 A novel Arabidopsis thaliana protein, ABAP1 INTERACTING PROTEIN 10, mediates crosstalk between the cell cycle and primary metabolism
MONTESSORO, P.; PAIXAO, J. F. R.; COSTA, C. N. M.; DUCATTI, L.; GRANGEIRO, L. P. P.; FUSARO, A. F.; BALLESTEROS, H. F.; IURIF, V.; CABRAL, L. M.; ANDRADE, J. C. D.; TESSARO, L.; BERNARDO, W. D. P.; SILVA COELHO, F.; ALMEIDA-ENGLER, J. D.; CAMPOSTRINI, E.; CONTE-JUNIOR, C. A.; HEMERLY, A. S.
10.1101/2024.11.20.624481 — plant biology — Posted on 2024-11-21
1327 Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors
Gomez-Munoz, M. A.; Ojeda-Puertas, M.; Luna-Ramirez, L.; Amador-Alvarez, A.; Rodriguez-Prieto, I.; Cordero Varela, J. A.; Pardal, R.; Vega, F. M.
10.1101/2024.11.20.624451 — cancer biology — Posted on 2024-11-21
1328 Characterizing the Solution Space of Migration Histories of Metastatic Cancers with MACH2
Roddur, M. S.; Ramavarapu, V.; Bunkum, A.; Huebner, A.; Minyev, R.; McGranahan, N.; Zaccaria, S.; El-Kebir, M.
10.1101/2024.11.19.624301 — cancer biology — Posted on 2024-11-21
1329 Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma
Purzner, J.; Brown, A. S.; Purzner, T.; Ellis, L.; Broski, S.; Litzenburger, U.; Andrews, K.; Sharma, A.; Wang, X.; Taylor, M. D.; Cho, Y.-J.; Fuller, M. T.; Scott, M. P.
10.1101/2024.11.21.624171 — cancer biology — Posted on 2024-11-21
1331 Aggregation and disaggregation of red blood cells: depletion versus bridging
Moreno, N.; Korneev, K.; Semenov, A.; Topuz, A.; Jhon, T.; Lettinga, M. P.; Ellero, M.; Wagner, C.; Fedosov, D. A.
10.1101/2024.11.20.624311 — biophysics — Posted on 2024-11-21
1336 Structural diversity and oligomerization of bacterial ubiquitin-like proteins
Gong, M.; Ye, Q.; Gu, Y.; Chambers, L. R.; Bobkov, A. A.; Arakawa, N. K.; Matyszewski, M.; Corbett, K. D.
10.1101/2024.11.21.623966 — biochemistry — Posted on 2024-11-21
1337 Reconstitution of SPO11-dependent double-strand break formation
Zheng, Z.; Zheng, L.; Arter, M.; Liu, K.; Yamada, S.; Ontoso, D.; Kim, S.; Keeney, S.
10.1101/2024.11.20.624382 — biochemistry — Posted on 2024-11-21
1338 Assessment of neurobehavioural traits under axenic conditions: an approach for multiple longitudinal analyses in the same mouse.
Rutsch, A.; Iachizzi, M.; Kirundi, J.; Kantsjoe, J. B.; Planchette, A. L.; Mueller, T.; Schmitz, W.; Radenovic, A.; Doenlen, R.; Gomez de Aguero, M.; Ronchi, F.
10.1101/2024.11.21.623170 — animal behavior and cognition — Posted on 2024-11-21
1341 CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation during cellular differentiation
Karpinska, M. A.; Zhu, Y.; Fakhraei Ghazvini, Z.; Ramasamy, S.; Barbieri, M.; Cao, N. T. B.; Lidschreiber, M.; Papantonis, A.; Oudelaar, A. M.
10.1101/2024.11.20.624447 — genomics — Posted on 2024-11-21
1342 TIRE-seq: an Integrated Sample Extraction and Transcriptomics Workflow for High Throughput Perturbation Studies
O'Keeffe, P.; Nouri, Y.; Saw, H. S.; Moore, Z.; Baldwin, T. M.; Olechnowicz, S. W. Z.; Jabbari, J. S.; Squire, D. M.; Leslie, S.; Wang, C.; You, Y.; Ritchie, M. E.; Cross, R. S.; Jenkins, M. R.; Audiger, C.; Naik, S. H.; Whittle, J. R.; Freytag, S.; Best, S. A.; Hickey, P. F.; Amann-Zalcenstein, D.; Bowden, R.; Brown, D. V.
10.1101/2024.11.20.624406 — genomics — Posted on 2024-11-21
1347 Multi-modal refinement of the human heart atlas during the first gestational trimester
De Bono, C.; Xu, Y.; Kausar, S.; Herbane, M.; Humbert, C.; Rafatov, S.; Missirian, C.; Moreno, M.; Shi, W.; Gitton, Y. I.; Lombardini, A.; Vanzetta, I.; Mazaud-Guittot, S.; Chedotal, A.; Baudot, A.; Zaffran, S.; Etchevers, H. C.
10.1101/2024.11.21.624698 — developmental biology — Posted on 2024-11-21
1348 PFAS Compounds PFOA and Gen X are Teratogenic to Sea Urchin Embryos
Lion, A. T.; Bodine, S. M.; McCutcheon, K. R.; Ghogale, M.; Chandragiri, S.; Abayawardena, D.; Shrestha, B. D.; Descoteaux, A. E.; Alvarez, K.; Balkman, J. A.; Cocke, B.; Wikramanayake, A.; Schlezinger, J.; Wong, J. Y.; Prakash, V. N.; Bradham, C.
10.1101/2024.11.21.624751 — developmental biology — Posted on 2024-11-21
1351 An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer
Xie, W.; Yu, X.; Yang, Q.; Ke, N.; Wang, P.; Kong, H.; Wu, X.; Ma, P.; Chen, L.; Yang, J.; Feng, X.; Wang, Y.; Shi, H.; Chen, L.; Liu, Y.-H.; Ding, B.-S.; Wei, Q.; Jiang, H.
10.1101/2024.11.19.624405 — immunology — Posted on 2024-11-21
1352 TRAIT: A Comprehensive Database for T-cell Receptor-Antigen Interactions
Wei, M.; Wu, J.; Bai, S.; Zhou, Y.; Chen, Y.; Zhang, X.; Zhao, W.; Chi, Y.; Pan, G.; Zhu, F.; Chen, S.; Zhou, Z.
10.1101/2024.11.20.624436 — immunology — Posted on 2024-11-21
1354 Measuring flicker induced vasodilation at a high spatial and temporal resolution in the human retina.
Senee, P.; Krafft, L.; Loukili, I.; Castro Farias, D.; Thouvenin, O.; Atlan, M.; Paques, M.; Meimon, S.; Mece, P.
10.1101/2024.11.20.624488 — neuroscience — Posted on 2024-11-21
1357 Pupillometry and Whole-Brain c-Fos Mapping Uncover Multimodal Mirror Mechanisms in Emotional Contagion Networks of Mice
Caldarelli, M.; Zucca, S.; Viglione, A.; Stella, A.; Nisar, R.; Sagona, G.; Papini, E. M.; Carrara, F.; Bovetti, S. M.; Mazziotti, R. M.; Pizzorusso, T.
10.1101/2024.11.20.624327 — neuroscience — Posted on 2024-11-21
1358 Astrocyte-specific secretome profiling reveals its correlation with neurological disorders
Liu, J.; Gao, J.; Guo, L.; Ma, G.; Guan, M.; Xia, C.; He, J.; Yang, Y.; Wu, Y.; Xu, J.; Xiong, L.; Yu, C.-Y.; Pei, G.; Zhao, J.; He, J.; Zhang, Y.; Wang, W.
10.1101/2024.11.21.624658 — neuroscience — Posted on 2024-11-21
1365 SIGNAL: Dataset for Semantic and Inferred Grammar Neurological Analysis of Language
Komissarenko, A.; Voloshina, E.; Cheveleva, A.; Semenkov, I.; Serikov, O.; Ossadtchi, A.
10.1101/2024.11.20.624526 — neuroscience — Posted on 2024-11-21
1369 Heterogeneous endocrine cell composition defines human islet functional phenotypes
Evans-Molina, C.; Pettway, Y. D.; Saunders, D. C.; Sharp, S. A.; Bate, T. S.; Sun, H.; Durai, H.; Mei, S.; Coldren, A.; Davis, C.; Reihsmann, C. V.; Hopkirk, A. L.; Taylor, J.; Bradley, A.; Aramandla, R.; Poffenberger, G.; Eskaros, A.; Jenkins, R.; Shi, D.; Kang, H.; Rajesh, V.; Thaman, S.; Feng, F.; Cartailler, J.-P.; Powers, A. C.; Abraham, K.; Gloyn, A. L.; Niland, J. C.; Brissova, M.
10.1101/2024.11.20.623809 — physiology — Posted on 2024-11-21
1378 Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping
Postrach, D.; Pritchard, C. E. J.; Frank, L.; van Leeuwen, T.; Messal, H. A.; Krimpenfort, P.; van Rheenen, J.; Rodewald, H.-R.
10.1101/2024.11.20.624484 — developmental biology — Posted on 2024-11-21
1379 Agouti and BMP signaling drive a naturally occurring fate conversion of melanophores to leucophores in zebrafish
Huang, D.; Kapadia, E.; Liang, Y.; Shriver, L. P.; Dai, S.; Patti, G. J.; Humbel, B. M.; Laudet, V.; PARICHY, D. M.
10.1101/2024.11.20.624586 — developmental biology — Posted on 2024-11-21
1380 Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions
Piersma, S. J.; Li, S.; Wong, P.; Bern, M. D.; Poursine-Laurent, J.; Yang, L.; Beckman, D. L.; Parikh, B. A.; Yokoyama, W. M.
10.1101/2024.06.04.597367 — immunology — Posted on 2024-11-21
1381 Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life
Corvilain, P.; Wens, V.; Bourguignon, M.; Capparini, C.; Fourdin, L.; Ferez, M.; Feys, O.; De Tiege, X.; Bertels, J.
10.1101/2023.10.28.564455 — neuroscience — Posted on 2024-11-21
1382 Hippocampal ripples predict motor learning during brief rest breaks in humans
Sjogard, M.; Baxter, B.; Mylonas, D.; Thompson, M.; Kwok, K.; Driscoll, B.; Tolosa, A.; Shi, W.; Stickgold, R.; Vangel, M.; Chu, C. J.; Manoach, D. S.
10.1101/2024.05.02.592200 — neuroscience — Posted on 2024-11-21
1383 Axonal transcriptome reveals upregulation of PLK1 as a protective mechanism in response to increased DNA damage in FUSP525L spinal motor neurons
Zimyanin, V.; Dash, B. P.; Grossmann, D.; Simolka, T.; Glass, H.; Verma, R.; Khatri, V.; Deppmann, C. D.; Zunder, E. R.; Redemann, S.; Hermann, A.
10.1101/2024.11.20.624439 — neuroscience — Posted on 2024-11-21
1384 Intrinsic and extrinsic mechanisms alter neural cell fate specification in EPM1 Epilepsy
Forero, A.; Pravata, M. V.; Pipicelli, F.; Soloperto, A.; Di Matteo, F.; Bekjarova, Z.; Frenna, E.; Canafoglia, L.; Ragona, F.; Maccarrone, G.; Gonzalez Pisfil, M.; Whal-Schott, C.; Cernilogar, F. M.; Di Giaimo, R.; Cappello, S.
10.1101/2024.11.20.624470 — neuroscience — Posted on 2024-11-21
1385 Function of Cytochrome P450 CYP72A1182 in Metabolic Herbicide Resistance Evolution in Amaranthus palmeri Populations
Rigon, C. A. G.; Kupper, A.; Sparks, C.; Montgomery, J.; Peter, F.; Schepp, S.; Perez-Jones, A.; Tranel, P. J.; Beffa, R.; Dayan, F. E.; Gaines, T. A.
10.1101/2023.12.13.571468 — plant biology — Posted on 2024-11-21
1386 Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis
Ishka, M. R.; Sussman, H.; Hu, Y.; Alqahtani, M. D.; Craft, E.; Sicat, R.; Wang, M.; Yu, L.; Ait-Haddou, R.; Li, B.; Drakakaki, G.; Nelson, A.; Pineros, M.; Korte, A.; Jaremko, L.; Testerink, C.; Tester, M.; Julkowska, M. M.
10.1101/2024.04.09.588564 — plant biology — Posted on 2024-11-21
1387 Age-associated modulation of TREM1/2- expressing macrophages promotes melanoma progression and metastasis
Scotegagna, M.; Murad, R.; Bina, P.; Feng, Y.; Porritt, R.; Terskikh, A.; Tian, X.; Adams, P. D.; Vuori, K.; Ronai, Z. A.
10.1101/2024.11.20.624563 — cancer biology — Posted on 2024-11-21
1392 Amphibian and reptile dataset across different land-use types in Guinea-Bissau, West Africa
dos Reis-Silva, F.; Alves-Martins, F.; Martinez-Arribas, J.; Pizzigalli, C.; Seck, S.; Rainho, A.; Rocha, R.; Palmeirim, A. F.
10.1101/2024.11.21.624282 — ecology — Posted on 2024-11-21
1394 Annotating CryoET Volumes: A Machine Learning Challenge
Peck, A.; Yu, Y.; Schwartz, J.; Cheng, A.; Ermel, U. H.; Kandel, S.; Kimanius, D.; Montabana, E.; Serwas, D.; Siems, H.; Wang, F.; Zhao, Z.; Zheng, S.; Haury, M.; Agard, D.; Potter, C.; Carragher, B.; Harrington, K.; Paraan, M.
10.1101/2024.11.04.621686 — cell biology — Posted on 2024-11-21
1395 PTEN Regulates Myofibroblast Activation in Valvular Interstitial Cells based on Subcellular Localization
Batan, D.; Tseropoulos, G.; Bishop, C.; Kirkpatrick, B. E.; Bera, K.; Khang, A.; Weiser-Evans, M. C.; Anseth, K. S.
10.1101/2024.06.30.601424 — cell biology — Posted on 2024-11-21
1399 Hepatic mitochondrial respiration is crucial for euthermia in complex III-deficient mice with impaired brown adipose tissue thermogenesis
Banerjee, R.; Upadhyay, D.; Zarybnicky, T.; Kietz, C.; Kuure, S.; Fellman, V.; Purhonen, J.; Kallijärvi, J.
10.1101/2024.09.23.612616 — physiology — Posted on 2024-11-21
1402 A cross-species framework for investigating perceptual evidence accumulation
Chakravarty, S.; Delgado-Sallent, C.; Kane, G. A.; Xia, H.; Do, Q.; Senne, R. A.; Scott, B.
10.1101/2024.04.17.589945 — animal behavior and cognition — Posted on 2024-11-21
1405 CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models
Shi, C.; Fan, J.; Deng, Z.; Liu, H.; Kang, Q.; Li, Y.; Guo, J.; Wang, J.; Gong, J.; Liao, S.; Chen, A.; Zhang, Y.; Li, M.
10.1101/2024.11.20.619750 — cell biology — Posted on 2024-11-21
1406 Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems
Datta, R.; Miskolci, V.; Gallego Lopez, G. M.; Britt, E.; Gillette, A.; Kralovec, A.; Giese, M. A.; Qian, T.; Votava, J.; Fan, J.; Huttenlocher, A.; Skala, M. C.
10.1101/2024.07.26.605362 — immunology — Posted on 2024-11-21
1407 Synchronous activation of striatal cholinergic interneurons induces local serotonin release
Matityahu, L.; Hobel, Z. B.; Berkowitz, N.; Malgady, J. M.; Gilin, N.; Plotkin, J. L.; Goldberg, J. A.
10.1101/2024.11.03.621726 — neuroscience — Posted on 2024-11-21
1408 Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves motor execution
Malfatti, T.; Velica, A.; Winne, J.; Ciralli, B.; Henriksson, K.; Nascimento, G.; Leao, R.; Kullander, K.
10.1101/2024.03.10.584276 — neuroscience — Posted on 2024-11-21
1411 A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
Saunders, R. A.; Allen, W. E.; Pan, X.; Sandhu, J.; Lu, J.; Lau, T. K.; Smolyar, K.; Sullivan, Z.; Dulac, C.; Weissman, J. S.; Zhuang, X.
10.1101/2024.11.18.624217 — genomics — Posted on 2024-11-21
1412 Dissecting the cis-regulatory syntax of transcription initiation with deep learning
Cochran, K.; Yin, M.; Mantripragada, A.; Schreiber, J.; Marinov, G. K.; Shah, S. R.; Yu, H.; Lis, J. T.; Kundaje, A.
10.1101/2024.05.28.596138 — genomics — Posted on 2024-11-21
1414 Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar
Miraldo, A.; Sundh, J.; Iwaszkiewicz-Eggebrecht, E.; Buczek, M.; Goodsell, R.; Johansson, H.; Fisher, B. L.; Raharinjanahary, D.; Rajoelison, E. T.; Ranaivo, C.; Randrianandrasana, C. E.; Rafanomezantsoa, J.-J.; Manoharan, L.; Granqvist, E.; van Dijk, L. J. A.; Ahlberg, L.; Ahlen, D.; Aspebo, M.; Aström, S.; Bellviken, A.; Bergman, P.-E.; Björklund, S.; Björkman, M. P.; Deng, J.; Desborough, L.; Dolff, E.; Eliasson, A.; Elmquist, H.; Emanuelsson, H. Z. S.; Erixon, R.; Fahlen, L.; Frogner, C.; Fürst, P.; Grabs, A.; Grudd, H.; Guasconi, D.; Gunnarsson, M.; Häggqvist, S.; Hed, A.; Hörnströ
10.1101/2024.10.24.619818 — ecology — Posted on 2024-11-21
1415 Using split protein reassembly strategy to control PLD enzymatic activity
yao, y.; Hu, C.; Li, J.; Lou, X.; Chen, G.; Qian, X.; He, L.; Li, X.; Zhang, P.; Xu, Y.; Li, H.
10.1101/2024.01.27.577557 — cell biology — Posted on 2024-11-21
1416 Relation of CMV and brain atrophy to trajectories of immunosenescence in diverse populations
Touil, H.; Luquez, T.; Comandante-Lou, N.; Lee, A. J.; Fujita, M.; Habeck, C.; Kroshilina, A.; Hegewisch-Solloa, E.; McInvale, J.; Zuroff, L.; Isnard, S.; Walker, E.; Zhang, L.; Routy, J.-P.; Zhang, Y.; Mace, E. M.; Klotz, L.; Wiendl, H.; Xia, Z.; Bar-Or, A.; Menon, V.; Stern, Y.; De Jager, P. L.
10.1101/2024.10.07.614568 — immunology — Posted on 2024-11-21
1420 Fronto-motor circuits linked to subclinical apathy
Derosiere, G.; Vassiliadis, P.; Dricot, L.; Dessain, Q.; Delinte, N.; Zenon, A.; Duque, J.
10.1101/2024.10.07.616861 — neuroscience — Posted on 2024-11-21
1421 Conserved moiety fluxomics
Fleming, R. M.; Haraldsdottir, H. S.; Preciat, G.; Huang, L.; Thiele, I.; Harms, A. C.; Hankemeier, T.
10.1101/2024.11.21.624666 — systems biology — Posted on 2024-11-21
1422 Non-genetic adaptation by collective migration
Vo, L.; Avgidis, F.; Mattingly, H.; Edmonds, K.; Burger, I.; Balasubramanian, R.; Shimizu, T. S.; Kazmierczak, B. I.; Emonet, T.
10.1101/2024.01.02.573956 — systems biology — Posted on 2024-11-21
1424 Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax
Jones, D.; Woods, E.; Li, Z.; Schaller, K. L.; Hoffmeyer, E.; Kooiman, B.; Fernandez, J.; Wharton, T.; Tufa, D.; Hall, S. C.; Trahan, G.; Maloney, K.; Pacenta, H.; Sullivan, K.; Espinosa, J.; Roede, J. R.; Marentette, J.; Stevens, B.; Inguva, A.; Stephenson, D.; Reisz, J. A.; D'Alessandro, A.; Jordan, C. T.; Yang, J. J.; Verneris, M. R.
10.1101/2024.09.30.615872 — cancer biology — Posted on 2024-11-21
1425 PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
Wang, J.; Shi, Y.; Wang, Y.; Shen, Y.; Liu, H.; Sun, S.; Wang, Y.; Zhou, X.; Zhou, Y.; Zeng, X.; Li, J.; Chen, Q.
10.1101/2024.07.23.604769 — cancer biology — Posted on 2024-11-21
1426 Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs
Saintilnord, W. N.; Hegazy, Y. A.; Chesnutt, K.; Eckstein, M.; Cassidy, R. N.; Dhahri, H.; Bennett, R. L.; Melters, D. P.; Lopes, E.; Fu, Z.; Lau, K.; Chandler, D. P.; Poirier, M. G.; Dalal, Y.; Licht, J. D.; Fondufe-Mittendorf, Y.
10.1101/2024.11.18.624207 — cancer biology — Posted on 2024-11-21
1430 Unravelling the molecular activation of the reparative cardiac fibroblasts after myocardial infarction
Hernandez, S. C.; Ainciburu, M.; Sudupe, L.; Planell, N.; Vilas-Zornoza, A.; Lopez-Moreno, M.; Sarvide, S.; Diaz-Martinez, L.; Cobos-Figueroa, J.; San Martin-Uriz, P.; Muinos-Lopez, E.; Abizanda, G.; Ripalda-Cemborain, P.; Lagani, V.; Romero, J. P.; Tegner, J.; Perez-Pomares, J. M.; Wu, M.; Janssens, S.; Prosper, F.; Ruiz-Villalba, A.; Gomez-Cabrero, D.
10.1101/2024.11.21.624638 — bioinformatics — Posted on 2024-11-21
1431 An Open Access Resource for Marmoset Neuroscientific Apparatus
Rollin, I. Z.; Papoti, D.; Bishop, M.; Szczupak, D.; Corigliano, M. R.; Hitchens, T. K.; Zhang, B.; Pell, S. K. A.; Guretse, S. S.; Dureux, A.; Murai, T.; Rizzo, S. J. S.; Klassen, L. M.; Zeman, P.; Gilbert, K. M.; Menon, R. S.; Lin, M.-K.; Everling, S.; Silva, A. C.; Schaeffer, D. J.
10.1101/2024.11.12.623252 — bioengineering — Posted on 2024-11-21
1436 A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats
Toh, H.; Au Yeun, W. K.; Unoki, M.; Matsumoto, Y.; Miki, Y.; Matsumura, Y.; Baba, Y.; Sado, T.; Nakamura, Y.; Matsuda, M.; Sasaki, H.
10.1101/2024.11.19.624036 — genetics — Posted on 2024-11-21
1437 Redistribution of ancestral functions underlies the evolution of venom production in marine predatory snails
Zancolli, G.; Modica, M. V.; Puilladre, N.; Kantor, Y.; Barua, A.; Campli, G.; Robinson-Rechavi, M.
10.1101/2024.09.09.612013 — evolutionary biology — Posted on 2024-11-21
1441 Unveiling the functional heterogeneity of endogenous tissue extracellular vesicles in skeletal muscle through multi-omics
Wang, Y.; Lou, P.; Zhou, X.; Xie, Y.; Zhang, Y.; Liu, S.; Li, L.; Lu, Y.; Wan, M.; Cheng, J.; Liu, J.
10.1101/2024.11.20.624461 — cell biology — Posted on 2024-11-21
1443 A composite subunit vaccine confers full protection against Buruli ulcer disease in the mouse footpad model of Mycobacterium ulcerans infection
Boakye-Appiah, J. K.; Tran, A. C.; Paul, M. J.; Hart, P.; Phillips, R. O.; Harrison, T. S.; Wansbrough-Jones, M.; Reljic, R.
10.1101/2024.11.21.624625 — immunology — Posted on 2024-11-21
1445 Common patterns of spatial selectivity in early visual cortex and face-selective brain regions
Morsi, A. Y.; Chow-Wing-Bom, H. T.; Schwarzkopf, D. S.; Goffaux, V.; Dekker, T. M.; Greenwood, J. A.
10.1101/2024.05.14.594166 — neuroscience — Posted on 2024-11-21
1448 Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model
Lentini, V.; Uras, G.; Manca, A.; El Faqir, M. A.; Lucas Del Pozo, S.; Deiana, N.; Cao, G.; Schapira, A. H.; Pantaleo, A.
10.1101/2024.10.25.620204 — neuroscience — Posted on 2024-11-21
1451 Loss of E3 ligase HvST1 function substantially increases recombination
Orr, J. N.; Mittmann, S. U.; Ramsay, L.; Lewandowska, D.; Barakate, A.; Macaulay, M.; McCallum, N.; Waugh, R.; Colas, I.
10.1101/2023.05.19.541444 — plant biology — Posted on 2024-11-21
1453 Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography
Brueck, J.; Schauenburg, D.; Kuan, S. L.; Goettert, S.; Klasen, B.; Frommberger, V.; Ebadi Jalal, K.; Boui, N.; Kwiatkowski, A.; Schake, L.; Bopp, T.; Bohn, T.; Weil, T.; Schreckenberger, M.; Miederer, M.
10.1101/2024.11.21.624628 — cancer biology — Posted on 2024-11-21
1455 Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
Jacob, J.; Anami, Y.; High, P.; Liang, Z.; Subramanian, S.; Ghosh, S. C.; AghaAmiri, S.; Guernsey-Biddle, C.; Tran, H.; Rowe, J. H.; Azhdarinia, A.; Tsuchikama, K.; Carmon, K. S.
10.1101/2024.02.20.581056 — cancer biology — Posted on 2024-11-21
1456 Towards robust machine olfaction: debiasing GC-MS data enhances prostate cancer diagnosis from urine volatiles
Rotteveel, A.; Lee, W.-Y.; Kountouri, Z.; Stefanou, N.; Kivell, H.; Gluck, C.; Zhang, S.; Mershin, A.
10.1101/2024.11.19.624273 — cancer biology — Posted on 2024-11-21
1458 Three STEPs forward: A trio of unexpected structures of PTPN5
Guerrero, L.; Ebrahim, A.; Riley, B. T.; Kim, S. H.; Bishop, A. C.; Wu, J.; Han, Y. N.; Tautz, L.; Keedy, D. A.
10.1101/2024.11.20.624168 — biophysics — Posted on 2024-11-21
1459 Laser Flash Melting Cryo-EM Samples to Overcome Preferred Orientation
Straub, M. S.; Harder, O. F.; Mowry, N. J.; Barrass, S. V.; Hruby, J.; Drabbels, M.; Lorenz, U. J.
10.1101/2024.11.21.624652 — biophysics — Posted on 2024-11-21
1467 Exploring Mechanisms of Action in Combinatorial Therapies through Solubility Alterations: Advancing AML Treatment
Gholizadeh, E.; Zangene, E.; Vadadokhau, U.; Ritz, D.; Soliymani, R.; Miettinen, J. J.; Baumann, M.; Wilhelm, M.; Heckman, C. A.; Saei, A. A.; Jafari, M.
10.1101/2024.11.08.618644 — biochemistry — Posted on 2024-11-21
1475 Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes
Baur, M.; Schulz, N. K. E.; Greune, L.; Langer, Z. M.; Eirich, J.; Finkemeier, I.; Peuss, R.; Dersch, P.; Kurtz, J.
10.1101/2024.11.21.624623 — evolutionary biology — Posted on 2024-11-21
1476 A transcontinental experiment elucidates (mal)adaptation of a cosmopolitan plant to climate in space and time
Albano, L. J.; Bastias, C. C.; Estarague, A.; Hendrickson, B. T.; Innes, S. G.; King, N.; Patterson, C. M.; Tudoran, A.; Vasseur, F.; Puentes, A.; Violle, C.; Kooyers, N. J.; Johnson, M. T.
10.1101/2024.09.16.613311 — evolutionary biology — Posted on 2024-11-21
1481 Real-Time Imaging of Antimalarial Drug Effects on Plasmodium falciparum-Infected Red Blood Cells
Wallner, J. S.; Bonsen, M.; Mathis, E.; Gomes, A. R.; Spangenberg, T.; Guizetti, J.
10.1101/2024.11.21.624618 — cell biology — Posted on 2024-11-21
1482 Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts
Du, H.; Rose, J. P.; Bons, J.; Guo, L.; Valentino, T. R.; Wu, F.; Burton, J. B.; Basisty, N.; Manwaring-Mueller, M.; Makhijani, P.; Chen, N.; Chang, V.; Winer, S.; Campisi, J.; Furman, D.; Nagy, A.; Schilling, B.; Winer, D. A.
10.1101/2024.11.18.623471 — cell biology — Posted on 2024-11-21
1483 Human spermatogenesis leads to a reduced nuclear pore structure and function
dos Santos, A.; Knowles, O.; Dendooven, T.; Hale, T.; Hale, V. L.; Burt, A.; Kolata, P.; Cannone, G.; Bellini, D.; Barford, D.; Allegretti, M.
10.1101/2024.10.30.620797 — cell biology — Posted on 2024-11-21
1484 A compendium of bona fide reference markers of plant-derived extracellular vesicles and their degree of phylogenetic conservation
Rodriguez de Lope, M. M.; Sanchez-Pajares, I. R.; Herranz, E.; Lopez-Vazquez, C. M.; Gonzalez-Moro, A.; Rivera-Tenorio, A.; Gonzalez-Sanz, C.; Sacristan, S.; Chicano-Galvez, E.; de la Cuesta, F.
10.1101/2024.11.21.624247 — molecular biology — Posted on 2024-11-21
1487 Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma
Toyonaga, T.; Kato, T.; Kawamoto, A.; Miyata, T.; Kawakami, K.; Fujita, J.; Hamaguchi, T.; Namba, K.; Miyata, M.
10.1101/2024.06.11.597861 — microbiology — Posted on 2024-11-21
1489 From high protection to lethal effect: diverse outcomes of immunization against invasive candidiasis with different Candida albicans extracellular vesicles
Martinez-Lopez, R.; Molero, G.; Parra-Giraldo, C.; Cabeza, M.; Castejon, G.; Garcia-Duran, C.; Clemente, F.; Hernaez-Sanchez, M. L.; Gil, C.; Monteoliva, L.
10.1101/2024.11.21.624473 — microbiology — Posted on 2024-11-21
1492 Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
Borodovich, T.; Wilson, J. S.; Bardy, P.; Smith, M.; Hill, C.; Khokhlova, E. V.; Govi, B.; Fogg, P. C.; Hill, C.; Shkoporov, A. N.
10.1101/2024.11.15.623857 — microbiology — Posted on 2024-11-21
1496 Mora-ERP-based RNN-Transformer for decoding single-trial EEGs during silent Japanese speeches
Yamazaki, T.; Kudo, S.; Kamata, S.-i.; Fujii, S.; Tsukiyama, S.; Yata, T.; Aoki, S.
10.1101/2024.11.18.624218 — neuroscience — Posted on 2024-11-21
1497 Visuoinertial and visual feedback in online steering control
Liu, J.-Y.; Cooke, J. R. H.; Selen, L. P. J.; Medendorp, W. P.
10.1101/2024.11.20.624619 — neuroscience — Posted on 2024-11-21
1498 Sleep need driven oscillation of glutamatergic synaptic phenotype
Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.
10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-11-21
1500 Disease modification upon brief exposure to tofacitinib during chronic epilepsy.
Hoffman, O. R.; Koehler, J. L.; Espina, J. E. C.; Patterson, A. M.; Gohar, E. S.; Coleman, E.; Schoenike, B. A.; Espinosa-Garcia, C.; Paredes, F.; Varvel, N. H.; Dingledine, R. J.; Maguire, J. L.; Roopra, A.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2024-11-21
1504 Longitudinal blood microsampling and proteome monitoring facilitate timely intervention in experimental type 1 diabetes
Parajuli, A.; Bendes, A.; Byvald, F.; Stone, V.; Ringqvist, E. E.; Butrym, M.; Angelis, E.; Kipper, S.; Bauer, S.; Roxhed, N.; Schwenk, J.; Flodstrom-Tullberg, M.
10.1101/2024.11.19.624292 — systems biology — Posted on 2024-11-21
1507 Design of allosteric modulators that change GPCR G protein subtype selectivity
Moore, M. N.; Person, K. L.; Alwin, A.; Krusemark, C. L.; Foster, N.; Ray, C.; Inoue, A.; Jackson, M. R.; Sheedlo, M. J.; Barak, L. S.; Fernandez de Velasco, E. M.; Olson, S. H.; Slosky, L. M.
10.1101/2024.11.20.624209 — pharmacology and toxicology — Posted on 2024-11-21
1508 Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis
Cleven, A.; Meringa, A. D.; Brazda, P.; Fasci, D.; Koorman, T.; Aarts, T.; Johanna, I.; Beringer, D. X.; Hernandez-Lopez, P.; Heijhuurs, S.; Mizutani, T.; Lim, S.; Huismans, M.; Bernink, J.; Diaz, D. V.; Wu, W.; Jose, E. S.; Schipper, J.; Tsakirakis, N.; van Heyningen, L. H.; Nouwens, A.; Gatti, L.; Straetemans, T.; Snippert, H.; Roodhart, J.; Derksen, P. W. B.; Drost, J.; Altelaar, M.; Heck, A. J. R.; Clevers, H.; Kuball, J.; Sebestyen, Z.
10.1101/2024.11.19.624272 — cancer biology — Posted on 2024-11-21
1509 FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer
Menon, S.; Gracilla, D.; Breese, M. R.; Lin, Y. P.; Dela Cruz, F. S.; Feinberg, T.; De Stanchina, E.; Galic, A.-F.; Allegakoen, H.; perati, s.; Wen, N.; Heslin, A.; Horlbeck, M.; Weissman, J. S.; Sweet-Cordero, A.; Bivona, T.; Tulpule, A.
10.1101/2023.04.30.538578 — cancer biology — Posted on 2024-11-21
1513 Unravelling the molecular activation of the reparative cardiac fibroblasts after myocardial infarction
Hernandez, S. C.; Ainciburu, M.; Sudupe, L.; Planell, N.; Vilas-Zornoza, A.; Lopez-Moreno, M.; Sarvide, S.; Diaz-Martinez, L.; Cobos-Figueroa, J.; San Martin-Uriz, P.; Muinos-Lopez, E.; Abizanda, G.; Ripalda-Cemborain, P.; Lagani, V.; Romero, J. P.; Tegner, J.; Perez-Pomares, J. M.; Wu, M.; Janssens, S.; Prosper, F.; Gomez-Cabrero, D.; Ruiz-Villalba, A.
10.1101/2024.11.21.624638 — bioinformatics — Posted on 2024-11-21
1515 In Situ Integration of Porous Polyethylene Nanomembrane with Wound Exudates for Scarless Healing
Yuan, S.; Gu, Q.; Guo, X.; Tang, X.; Qiu, J.; Shang, L.; Lin, J. Q.; Weng, L.-t.; Gao, P.
10.1101/2024.11.19.624279 — bioengineering — Posted on 2024-11-21
1519 Multi-year drought strengthens positive and negative functional diversity effects on tree growth response
Serrano-Leon, H.; Blondeel, H.; Glenz, P.; Steurer, J.; Schnabel, F.; Baeten, L.; Guillemot, J.; Martin-StPaul, N.; Skiadaresis, G.; Scherer-Lorenzen, M.; Bonal, D.; Boone, M.; Decarsin, R.; Druel, A.; Godbold, D. L.; Gong, J.; Hajek, P.; Jactel, H.; Koricheva, J.; Mereu, S.; Ponette, Q.; Rewald, B.; Sanden, H.; Van den Bulcke, J.; Verheyen, K.; Werner, R.; Bauhus, J.
10.1101/2024.11.21.622593 — ecology — Posted on 2024-11-21
1521 Desmoplakin is a desmosomal mechanosensor
Dong, Y.; Elgerbi, A.; Xie, B.; Choy, J. S.; Sivasankar, S.
10.1101/2024.11.19.624364 — cell biology — Posted on 2024-11-21
1522 Aspergillus nidulans Transcription Factor BrlA is Utilized in a Conidiation-Independent Response to Cell-Wall Stress
Edwards, H.; Zavorskas, J.; Huso, W.; Doan, A. G.; Lee, J.; Morse, M. E.; Wilkinson, H. H.; Ebbole, D.; Shaw, B.; Harris, S.; Srivastava, R.; Marten, M. R.
10.1101/2024.11.21.624663 — cell biology — Posted on 2024-11-21
1524 Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting cysteines in the C-terminal domain of GluN2B subunits: implications for synaptic plasticity
Fiumelli, H.; Herrera-Lopez, G.; Lemtiri-Chlieh, F.; Mottier, L.; Girgis, J.; Ben-Adiba, C.; Jourdain, P.; Carrano, N.; Mahmood, H.; Ooi, A.; Arold, S. T.; Di Luca, M.; Gardoni, F.; Magistretti, P. J.
10.1101/2024.11.21.624499 — neuroscience — Posted on 2024-11-21
1525 Severe traumatic brain injury temporally affects cerebral blood flow, endothelial cell phenotype, and cilia
Gupta, A.; Bice, Z.; Chen, V.; Chen, Y.; Veltri, A. J.; Lin, C.-W.; Ma, X.; Pan, A. Y.; Zennadi, R.; Palecek, S. P.; Mohieldin, A. M.; Nauli, S. M.; Ramchandran, R.; Rarick, K. R.
10.1101/2024.11.19.623875 — neuroscience — Posted on 2024-11-21
1528 Clinical and Molecular Characterization of Glioma Patients: miR-21 Expression as a Prognostic Biomarker in Tissue and Serum
Laghari, A. A.; Sufiyan, S.; Amin, W.; Adnan, U.; Naeem, S.; Abidi, S. H.; Ilyas, S.; Uddin, S.; Bajwa, M. H.; Enam, S. A.; Mughal, N.
10.1101/2024.11.20.624501 — molecular biology — Posted on 2024-11-21
1529 A deep neural network to de-noise single-cell RNAsequencing data
Sharifitabar, M.; Kazempour, S.; Razavian, J.; Sajedi, S.; Solhjoo, S.; Zare, H.
10.1101/2024.11.20.624552 — bioinformatics — Posted on 2024-11-21
1531 Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs
Saintilnord, W. N.; Hegazy, Y. A.; Chestnutt, K.; Eckstein, M.; Cassidy, R. N.; Dhahri, H.; Bennett, R. L.; Melters, D. P.; Lopes, E.; Fu, Z.; Lau, K.; Chandler, D. P.; Poirier, M. G.; Dalal, Y.; Licht, J. D.; Fondufe-Mittendorf, Y.
10.1101/2024.11.18.624207 — cancer biology — Posted on 2024-11-21
1532 Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity
Pasquier, N.; Isomursu, A.; Hamidi, H.; Mathieu, J. R. R.; Härkönen, J.; Follain, G.; Desterke, C.; Fusilier, Z.; Solis, J.; Belaya, I.; Kankaanpää, P.; Barresi, V.; Cartry, J.; Bedja, S.; Jaulin, F.; Ivaska, J.
10.1101/2024.11.20.624298 — cancer biology — Posted on 2024-11-21
1533 A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
Saunders, R. A.; Allen, W. E.; Pan, X.; Sandhu, J.; Lu, J.; Lau, T. K.; Smolyar, K.; Sullivan, Z.; Dulac, C.; Weissman, J. S.; Zhuang, X.
10.1101/2024.11.18.624217 — genomics — Posted on 2024-11-21
1536 Postglacial recolonization of the Southern Ocean by elephant seals occurred from multiple glacial refugia
Berg, A.; Askew, M.; Seersholm, F.; Verry, A.; Hoelzel, A. R.; Welch, A.; Greig, K.; Walter, R.; Knapp, M.; Barlow, A.; Paijmans, J.; Waters, J.; Bunce, M.; McDonald, K.; O'Connor, S.; Hall, B.; Koch, P. L.; Baroni, C.; Salvatore, M. C.; Faulkner, P.; Ho, S. Y. W.; Rawlence, N. J.; de Bruyn, M.
10.1101/2024.11.18.622576 — ecology — Posted on 2024-11-21
1539 Optimizing PSC culture for generating neural organoids
Sutcliffe, M. A.; Jensen, P.; Tan, J.; Morris, C. A. J.; Fazakerley, D. J.; Larsen, M. R.; Lancaster, M. A.
10.1101/2024.11.20.624444 — cell biology — Posted on 2024-11-21
1540 Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship
Stevenson, N.; Thompson, G.; Hoyle, A.; Lewis, P. A.; Prada-Sanchez, M. E.; Swift, J.; Heesom, K.; Lowe, M.; Stephens, D. J.
10.1101/2024.11.19.624265 — cell biology — Posted on 2024-11-21
1541 Defining the parameters for sorting of different RNA cargo into Extracellular vesicles
Batish, M.; Abdelgawad, A.; Huang, Y.; Gololobova, O.; Yu, Y.; Parashar, V.; Witwer, K. W.
10.1101/2024.11.20.624351 — cell biology — Posted on 2024-11-21
1544 Cingulate and striatal hubs are linked to early skill learning
Sugata, H.; Iwane, F.; Hayward, W.; Azzollini, V.; Dash, D.; Salamanca-Giron, R. F.; Bonstrup, M.; Buch, E. R.; Cohen, L.
10.1101/2024.11.20.624544 — neuroscience — Posted on 2024-11-21
1546 Pre-treatments of Ex vivo Vascularized Composite Allografts: A Scoping Review
Baker, C. E.; Stead, T. S.; Shah, A. R.; Pullmann, D.; Chinta, S.; Tran, D. L.; Brydges, H. T.; Laspro, M.; Gelb, B. E.; Rodriguez, E. D.; Rabbani, P. S.
10.1101/2024.11.20.624373 — systems biology — Posted on 2024-11-21
1548 Population genomics of Marchantia polymorpha subspecies ruderalis reveals evidence of climate adaptation
Dolan, L.; Wu, S.; Jandrasits, K.; Swarts, K.; Roetzer, J.; Akimcheva, S.; Shimamura, M.; Hisanaga, T.; Berger, F.
10.1101/2024.11.19.624281 — plant biology — Posted on 2024-11-21
1549 Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training
Hulmi, J. J.; Halonen, E. J.; Sharples, A. P.; O'Connell, T. M.; Kuikka, L.; Lappi, V.-M.; Salokas, K.; Keskitalo, S.; Varjosalo, M.; Ahtiainen, J. P.
10.1101/2024.11.19.624068 — physiology — Posted on 2024-11-21
1550 Mating and ecdysone signaling modify growth, metabolism, and digestive efficiency in the female Drosophila gut
Kandelouei, T. N.; Houghton, M. E.; Lewis, M. R.; Keller, C. C.; Marchetti, M.; Kang, X. N.; Edgar, B. A.
10.1101/2024.11.19.624434 — physiology — Posted on 2024-11-21
1551 Controlling human stem cell-derived islet composition using magnetic sorting
Kelley, A. B.; Shunkarova, M.; Maestas, M. M.; Gale, S. E.; Hogrebe, N. J.; Millman, J. R.
10.1101/2024.11.19.624394 — bioengineering — Posted on 2024-11-21
1555 Ancient climate changes and relaxed selection shape cave colonisation in North American cavefishes
Hart, P.; Rincon-Sandoval, M.; Melendez-Vazquez, F.; Armbruster, J.; Troyer, E.; Bierstein, O.; Gough, B.; Betancur-R, R.; Niemiller, M.; Arcila, D.
10.1101/2024.11.20.624529 — evolutionary biology — Posted on 2024-11-21
1558 Detection of Deltacoronavirus in Environmental Fecal Samples from Seabirds in the Saint Peter and Saint Paul Archipelago, central equatorial Atlantic Ocean
Gomes, F.; Correa, L.; da Silva, A. F.; Prado, T.; Bueno, M. G.; Appolinario, L.; Flores, P. S.; Resende, P. C.; Siqueira, M.; Brandao, M.; Reck, J.; Wallau, G. d. L.; Ogrzewalska, M.
10.1101/2024.11.19.624433 — molecular biology — Posted on 2024-11-21
1560 Phospholipid Scramblase 1 (PLSCR1) Regulates Interferon-Lambda Receptor 1 (IFN-lambdaR1) and IFN-lambda Signaling in Influenza A Virus (IAV) Infection
Yang, A. X.; Ramos-Rodriguez, L.; Sorkhdini, P.; Yang, D.; Norbrun, C.; Majid, S.; Zhang, Y.; Holtzman, M.; Boyd, D. F.; Zhou, Y.
10.1101/2024.11.20.624469 — immunology — Posted on 2024-11-21
1567 Strikingly different neurotransmitter release strategies in dopaminergic subclasses
Dorrego-Rivas, A.; Byrne, D. J.; Liu, Y.; Cheah, M.; Arslan, C.; Lipovsek, M.; Ford, M. C.; Grubb, M. S.
10.1101/2024.11.20.622499 — neuroscience — Posted on 2024-11-21
1568 Representation Learning of Human Disease Mechanisms for a Foundation Model in Rare and Common Diseases
Ravandi, B.; Mowrey, W. R.; Chatterjee, A.; Ricchiuto, P.; Haddadi, P.; Abdelmessih, M.; Ding, W.; Lambden, S.; Ughetto, M.; Barrett, I.; Diethe, T.; Del Angel, G.; Eliassi-Rad, T.
10.1101/2024.11.19.624381 — systems biology — Posted on 2024-11-21
1569 Deep Kernel Inversion: Rapid and Accurate Molecular Interaction Prediction for Drug Design
Myers, S. A.; Miller, C.; Lugo, K.; Trinh, T.; Lee, C.-w.; Arunachalam, N.; Chen, H.; Drygin, D.; Martineau, J.
10.1101/2024.11.19.624391 — systems biology — Posted on 2024-11-21
1570 Aphid effectors suppress plant immunity via recruiting defence proteins to processing bodies
Liu, Q.; Neefjes, A. C. M.; Kobylinska, R.; Mugford, S. T.; Marzo, M.; Canham, J.; Schuster, M.; van der Hoorn, R. A. L.; Chen, Y.; Hogenhout, S. A.
10.1101/2024.11.20.624400 — plant biology — Posted on 2024-11-21
1572 Design of allosteric modulators that change GPCR G protein subtype selectivity
Moore, M. N.; Person, K. L.; Alwin, A.; Krusemark, C. L.; Foster, N.; Ray, C.; Inoue, A.; Jackson, M. R.; Sheedlo, M. J.; Barak, L. S.; Olson, S. H.; Fernandez de Velasco, E. M.; Slosky, L. M.
10.1101/2024.11.20.624209 — pharmacology and toxicology — Posted on 2024-11-21
1573 Targeting STING in experimental peritoneal damage: a novel approach in peritoneal dialysis therapy
Marchant, V.; Garcia-Gimenez, J.; Gonzalez-Mateo, G. T.; Sandoval, P.; Tejedor-Santamaria, L.; Rayego-Mateos, S.; Ramos, R.; Jimenez-Heffernan, J.; Ortiz, A.; Raby, A.-C.; Lopez-Cabrera, M.; Ramos, A. M.; Ruiz-Ortega, M.
10.1101/2024.11.19.621845 — pathology — Posted on 2024-11-21
1574 Single-cell spatial mapping reveals alteration of cell type composition and tissue microenvironment during early colorectal cancer formation
Guha, T. K.; Esplin, E. D.; Horning, A. M.; Chiu, R.; Paul, K.; Weimer, A. K.; Becker, W. R.; Laquindanum, R.; Mills, M. A.; Esplin, D. G.; Shen, J.; Monte, E.; White, S.; Karathanos, T. V.; Cotter, D.; Bi, J.; Ladabaum, U.; Longacre, T. A.; Curtis, C.; Greenleaf, W. J.; Ford, J. M.; Snyder, M. P.
10.1101/2024.11.20.622725 — cancer biology — Posted on 2024-11-21
1576 HIF2α negatively regulates MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastoma.
Yuan, J.; Maitra, S.; Antoniou, E.; Zhu, J.; Li, W.; Demirel, I. S.; Toskas, K.; Martinez, I. L.; Ozcimen, L.; Lindehell, H.; Kogner, P.; Bedoya-Reina, O. C.; Schlisio, S.; Holmberg, J.
10.1101/2024.11.20.624001 — cancer biology — Posted on 2024-11-21
1578 Chaperonin TRiC bridges radial spokes for folding proteins locally translated in mammalian sperm flagella
Cong, Y.; Meng, X.; Li, L.; Lin, C.; Zhu, Y.; Feng, Y.; Zhou, X.; Tong, Y.; Wang, S.; Yin, G.; Liu, R.; Sun, F.; Yan, X.; Zhu, X.
10.1101/2024.11.19.624414 — biophysics — Posted on 2024-11-21
1579 The Protein Language Visualizer: Sequence Similarity Networks for the Era of Language Models
Herrera, J. E.; Garcia, M. F. M.; Bermejo, S. M.; Jasso, A. L.; Shi, K.; Mead, D.; Veskimägi, S. M.; O'Connor, M.; Siordia, A.; Roethler, N.; Jinich, A.
10.1101/2024.11.19.624229 — bioinformatics — Posted on 2024-11-21
1581 Gaia: A Context-Aware Sequence Search and Discovery Tool for Microbial Proteins
Jha, N.; Kravitz, J.; West-Roberts, J.; Camargo, A.; Roux, S.; Cornman, A.; Hwang, Y.
10.1101/2024.11.19.624387 — bioinformatics — Posted on 2024-11-21
1584 Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration
Deng, Z.; Tovani, C. B.; Bianco, S.; Comandini, G.; Elghajiji, A.; Adams, D. J.; Scarpa, F.; Whitehouse, M. R.; Seddon, A. M.; Armstrong, J. P. K.
10.1101/2024.11.20.624078 — bioengineering — Posted on 2024-11-21
1585 Cross-species Comparison of Ultramafic Rock Bio-accelerated Weathering Performance
Plante, L.; Klug, J. D.; Lee, J.; Hornby, A.; Adair, J.; Marecos, S.; Reid, M. C.; Gazel, E.; Barstow, B.
10.1101/2024.11.19.624384 — bioengineering — Posted on 2024-11-21
1586 Deep learning from videography as a tool for measuring infection in poultry
Scheidwasser, N.; Poulsen, L. L.; Khurana, M. P.; Iglesias-Carrasco, M.; Leow, P. R.; Laydon, D. J.; Donnelly, C. A.; Bojesen, A. M.; Bhatt, S.; Duchene, D. A.
10.1101/2024.11.20.624075 — animal behavior and cognition — Posted on 2024-11-21
1587 ERGA-BGE Reference Genome of the Northern chamois (Rupicapra rupicapra): Europe's most abundant mountain ungulate
Buzan, E.; Boncina, A.; Pokorny, B.; Escudero, N.; Fernandez, R.; Böhne, A.; Monteiro, R.; Gut, M.; Camara Ferreira, F.; Cruz, F.; Gomez-Garrido, J.; Alioto, T. S.; Haggerty, L.; Martin, F.; De Panis, D.
10.1101/2024.11.20.624344 — genomics — Posted on 2024-11-21
1592 Home range spillover in habitats with impassable boundaries: Causes, biases, and corrections using autocorrelated kernel density estimation
Hollins, J. P. W.; Hussey, N.; Harris, L.; Moore, J.-S.; Fleming, C.; Calabrese, J.; Noonan, M. J.; Fagan, W. F.; Alston, J. M.; Malley, B.
10.1101/2024.11.20.624379 — ecology — Posted on 2024-11-21
1594 Reintroduction of wild song culture to a critically endangered songbird
Appleby, D. L.; Langmore, N. E.; Pitcher, B.; Heinsohn, R.; Tripovich, J.; Matkovics, R.; Crates, R. A.
10.1101/2024.11.19.624418 — ecology — Posted on 2024-11-21
1595 A process-based model simulating the life cycle of Culex pipines s.s./Cx. torrentium in Germany
Rauhöft, L.; Duve, P.; Afonso, S. M. M.; Jöst, H.; Sulesco, T.; Sauer, F. G.; Lühken, R.
10.1101/2024.11.20.624534 — ecology — Posted on 2024-11-21
1597 Engineering assembloids to mimic graft-host skeletal muscle interaction
Rossi, L.; Auletta, B.; La Placa, M.; Cecconi, G.; Maghin, E.; Chiolerio, P.; Angiolillo, S.; Carraro, E.; Gagliano, O.; Laterza, C.; Elvassore, N.; Piccoli, M.; Urciuolo, A.
10.1101/2024.11.20.622615 — cell biology — Posted on 2024-11-21
1598 Delayed protein translocation protects mitochondria against toxic CAT-tailed proteins
Bertram, N.; Izawa, T.; Thoma, F.; Wagener, N.; Schwenkert, S.; Osman, C.; Neupert, W.; Mokranjac, D.
10.1101/2024.11.20.624519 — cell biology — Posted on 2024-11-21
1600 Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions
Verma, A.; Yu, C.; Bachl, S.; Lopez, I.; Schwartz, M. S.; Moen, E.; Kale, N.; Ching, C.; Miller, G.; Dougherty, T.; Pao, E.; Graf, W.; Ward, C.; Jena, S. G.; Marson, A.; Carnevale, J.; Van Valen, D. A.; Engelhardt, B. E.
10.1101/2024.11.19.624390 — cell biology — Posted on 2024-11-21
1601 Comamonas aquatica inhibits TIR-1/SARM1 induced axon degeneration
O'Connor, L. C.; Kang, W. K.; Vo, P.; Spinelli, J. B.; Alkema, M. J.; Byrne, A. B.
10.1101/2024.11.20.622298 — neuroscience — Posted on 2024-11-21
1602 Neural correlates of kinematic features of passive finger movement revealed by univariate and multivariate fMRI analyses
Pamplona, G. S. P.; Sulzer, J.; Beldzik, E.; Lambercy, O.; Ionta, S.; Gassert, R.; Lewis-Peacock, J. A.
10.1101/2024.11.20.624514 — neuroscience — Posted on 2024-11-21
1603 Development of novel signal and spike velocity analysis tools in peripheral nerve cuffs
Klus, J.; Boys, A. J.; Serrano, R. R.-M.; Malliaras, G. G.; Carnicer Lombarte, A.
10.1101/2024.11.20.624516 — neuroscience — Posted on 2024-11-21
1604 Integrative Computational Framework, Dyscovr, Links Mutated Driver Genes to Expression Dysregulation Across 19 Cancer Types
Geraghty, S. E.; Boyer, J. A.; Fazel-Zarandi, M.; Arzouni, N.; Ryseck, R.-P.; McBride, M. J.; Parsons, L. R.; Rabinowitz, J. D.; Singh, M.
10.1101/2024.11.20.624509 — systems biology — Posted on 2024-11-21
1605 Electrical charge-mediated transformation for efficient plant genome editing
Augustine, S. M.; Vadakan Cherian, A.; Paridhi, P.; Rashid, M. M.; Ugwuanyi, S.; Knoblauch, B.; Tzigos, S.; Pullamsetti, S. S.; Snowdon, R.
10.1101/2024.11.19.624257 — plant biology — Posted on 2024-11-21
1607 Negative resilience trends to more frequent extreme droughts in Mediterranean oak species
Vazquez, I. B.; Miranda, A. M.; Sancho, E. M.; Casal, A. R.; Salguero, R. S.; Resina, L. M.
10.1101/2024.11.19.624310 — ecology — Posted on 2024-11-20
1608 Mechanistic pathways of tick exposure risk in native and invaded plant communities
Hiatt, D.; Dillon, W.; Gardner, A.; Cabrera, S.; Dietze, M.; Allan, B.; Flory, S. L.
10.1101/2024.11.19.624319 — ecology — Posted on 2024-11-20
1610 Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy.
Carter, R. D.; Purnama, U.; Castro-Guarda, M.; Montes-Aparicio, C. N.; Chandran, A.; Mbasu, R.; Ruby, M.; Daly, C.; Buffa, F. M.; Heather, L. C.; Carr, C. A.
10.1101/2024.11.20.624467 — molecular biology — Posted on 2024-11-20
1611 RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription
Sadurni, M. M.; Jones, M. L.; Pavlou, L.; Radi, M.; Kompocholi, S.; Passaretti, P.; Gambus, A.; Gregersen, L. H.; Saponaro, M.
10.1101/2024.11.20.622938 — molecular biology — Posted on 2024-11-20
1612 The impact of transplant location on the gut microbiome and resistome in patients undergoing hematopoietic stem cell transplantation at home versus in the hospital
Andermann, T. M.; Zeng, K.; Guirales-Medrano, S.; Groth, A.; Ramachandran, B. C.; Sun, S.; Sorgen, A. A.; Hill, L.; Bush, A. T.; Liu, H.; Jones, C.; Roach, J.; Conlon, B. P.; Rao, G.; Chao, N. J.; Fodor, A. A.; Sung, A. D.
10.1101/2024.11.19.624359 — microbiology — Posted on 2024-11-20
1613 Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action
Johnson, W. C.; Alivisatos, A.; Smith, T. C.; Van, N.; Soni, V.; Wallach, J. B.; Clark, N. A.; Fitzgerald, T. A.; Whiteley, J. J.; Sokolov, A.; Ando, D. M.; Schnappinger, D.; Rhee, K. Y.; Aldridge, B. B.
10.1101/2024.11.20.623860 — microbiology — Posted on 2024-11-20
1615 Modulatory effect of plasma-activated water on arbuscular mycorrhizal symbiosis in Lotus japonicus
Cortese, E.; Binci, F.; Nouri, E.; Capparotto, A.; Settimi, A. G.; Dabala, M.; Antoni, V.; Squartini, A.; Giovannetti, M.; Navazio, L.
10.1101/2024.11.19.624245 — plant biology — Posted on 2024-11-20
1616 Assessing the performance of current strain resolution tools on long-read metagenomes
Afolayan, A. O.; Montano, S. A.; Akintayo, I. J.; Duarte dos Santos, L.; Reuter, S.
10.1101/2024.11.20.624313 — bioinformatics — Posted on 2024-11-20
1617 A proposed framework for evaluating meat alternatives
Semper, C.; Kolta, C.; Kinney, M.; Giali, J.; Rogers, M.; Blaustein-Rejto, D.; Rowat, A. C.; Ogilvie, O. J.; Hutmacher, R.; Wee, J.; Emery, I.; Domigan, L. J.; Shelke, K.
10.1101/2024.11.18.624184 — bioengineering — Posted on 2024-11-20
1620 Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response
Jain, K.; Tchara, P.-E. K.; Mengistalem, A. B.; Holland, A. P.; Bowman, C. N.; Marunde, M. R.; Popova, I. K.; Cooke, S. W.; Krajewski, K.; Keogh, M.-C.; Lambert, J.-P.; Strahl, B.
10.1101/2024.11.20.623956 — biochemistry — Posted on 2024-11-20
1621 Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci
Mullis, M. N.; Wright, K. M.; Raj, A.; Gatti, D. M.; Reifsnyder, P.; Flurkey, K.; Archer, J. R.; Robinson, L.; Di Franscesco, A.; Svenson, K. L.; Korstanje, R. M.; Harrison, D. E.; Ruby, J. G.; Churchill, G. A.
10.1101/2024.11.20.624531 — genetics — Posted on 2024-11-20
1624 A sequential event-responsive fluorescent reporter for inducible Cre and Flp combinatorial recombination
Pessina, G.; Camera, M.; Loiacono, F.; Uccelli, A.; Benfenati, F.; Medini, P.; Trovato, F.; Sato, S. S.
10.1101/2024.11.20.624546 — molecular biology — Posted on 2024-11-20
1625 The sequence and structural integrity of the SARS-CoV-2 Spike protein transmembrane domain is crucial for viral entry
Ortiz-Mateu, J.; Belda, D.; Aviles-Alia, A. I.; Alonso-Romero, J.; Garcia-Murria, M. J.; Mingarro, I.; Geller, R.; Martinez-Gil, L.
10.1101/2024.11.19.624333 — molecular biology — Posted on 2024-11-20
1628 Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation
Offersen, S. M.; Adamberg, S.; Spiegelhauer, M. R.; Mao, X.; Rasmussen, T. S.; Larsen, F.; Zhong, J.; Nguyen, D. N.; Nielsen, D. S.; Aunsholt, L.; Thymann, T.; Adamberg, K.; Brunse, A.
10.1101/2024.11.20.624498 — microbiology — Posted on 2024-11-20
1629 Transcriptional landscape of the archaeal cell cycle is broadly conserved in eukaryotes
Gomez-Raya-Vilanova, M. V.; Teuliere, J.; Medvedeva, S.; Dai, Y.; Corel, E.; Lopez, P.; Lapointe, F.-J.; Bhattacharya, D.; Haraoui, L.-P.; Turc, E.; Monot, M.; Cvirkaite-Krupovic, V.; Bapteste, E.; Krupovic, M.
10.1101/2024.11.20.624502 — microbiology — Posted on 2024-11-20
1630 The role of secondary structures of peptide polymers on antimicrobial efficacy and antibiotic potentiation
Barman, S.; Abiodun, A.; Hossain, M. W.; Parris, A.; Chandrasseril, A. B.; Older, E.; Li, J.; Decho, A.; Tang, C.
10.1101/2024.11.19.623429 — microbiology — Posted on 2024-11-20
1632 Computer assisted multi-level optimization of malonyl-CoA availability in Pseudomonas putida
Batianis, C.; van Rosmalen, R.; Monino Fernandez, P.; Asin-Garcia, E.; Martin-Pascual, M.; Jeschek, M.; Weusthuis, R.; Suarez Diez, M.; Martins dos Santos, V. A.
10.1101/2024.11.20.624107 — synthetic biology — Posted on 2024-11-20
1633 Photodynamic Therapy for Deep Organ Cancer by Implantable Wireless OLEDs
Itazaki, Y.; Sakanoue, K.; Fujita, K.; Kirino, I.; Eguchi, K.; Miyazono, Y.; Yamaguchi, R.; Tsunenari, T.; Sugihara, T.; Kuwada, K.; Kobayashi, N.; Goya, T.; Morii, K.; Tsujimoto, H.; Morimoto, Y.
10.1101/2024.11.18.624193 — bioengineering — Posted on 2024-11-20
1634 Engineered mitochondrial A-to-G editors with enhanced efficiency and targeting scope
Chen, L.; Hong, M.; Luan, C.; Yuan, M.; Wang, Y.; Guo, X.; Fang, Y.; Huang, H.; Dong, X.; Gao, H.; Zhang, D.; Chen, X.; Meng, D.; Huang, M.; Yi, Z.; Liu, M.; Gao, L.; Song, G.; Zhou, X.; Wei, W.; Li, D.
10.1101/2024.11.19.623682 — bioengineering — Posted on 2024-11-20
1637 A phased chromosome-level genome of the annelid tubeworm Galeolaria caespitosa
Van Dorssen, M.; Belcher, E. K.; Gallegos, C.; Hodgins, K.; Monro, K.
10.1101/2024.11.18.624032 — genomics — Posted on 2024-11-20
1638 Striking Departures from Polygenic Architecture in the Tails of Complex Traits
Souaiaia, T.; Wu, H. M.; Choi, S. W.; Ori, A. P. S.; Hoggart, C. J.; O'Reilly, P. F.
10.1101/2024.11.18.624155 — genetics — Posted on 2024-11-20
1641 Combining the CRISPR Activation and Interference Capabilities Using dCas9 and G-Quadruplex Structures
Kabir, M. L.; Kodikara, S. G.; Hoque, M. E.; Shiekh, S. A.; Alfehaid, J.; Basu, S.; Balci, H.
10.1101/2024.11.19.624357 — molecular biology — Posted on 2024-11-20
1648 A TORC1-PHR1 signaling axis regulates phosphorus starvation and immunity signaling network in Arabidopsis
Awasthi, P.; Jamsheer K, M.; Kumar, M.; Mishra, S.; Tiwari, A.; Jindal, S.; Saksena, H. B.; Singh, D.; Vadassery, J.; Rouached, H.; Meyer, C.; Laxmi, A.
10.1101/2024.11.18.624151 — plant biology — Posted on 2024-11-20
1650 Network toxicology focused investigation on the impacts of inorganic arsenic and cadmium on human and ecosystem health
Chivukula, N.; Madgaonkar, S. R.; Ramesh, K.; Mangot, S.; Karthikeyan, P.; Marigoudar, S. R.; Sharma, K. V.; Samal, A.
10.1101/2024.11.18.624172 — pharmacology and toxicology — Posted on 2024-11-20
1651 Cancer-associated DAXX mutations reveal a critical role for ATRX localization in ALT suppression
Clatterbuck Soper, S. F.; Walker, R. L.; Pineda, M. A.; Zhu, Y. J.; Dalgleish, J. L. T.; Wang, J.; Meltzer, P. S.
10.1101/2024.11.18.624165 — cancer biology — Posted on 2024-11-20
1658 Unveiling the Hidden Feast: translating molecular detection into predation rate. An example on biological control by generalist predators in agricultural fields.
MASSON, A. L.; Rastello, K.; Sacco-Martret de Preville, A.; Tricault, Y.; Poggi, S.; Canard, E.; Etienne, M.-P.; Plantegenest, M.
10.1101/2024.11.18.624133 — ecology — Posted on 2024-11-20
1659 Do rhizobia buffer legumes against climate-mediated microbiome effects?
Boyle, J. A.; Murphy, B.; Teng, F.; Zadeh, P. B.; Ensminger, I.; Stinchcombe, J. R.; Frederickson, M. E.
10.1101/2024.11.18.624153 — ecology — Posted on 2024-11-20
1661 Learning multi-cellular representations of single-cell transcriptomics data enables characterization of patient-level disease states
Liu, T.; De Brouwer, E.; Kuo, T.; Diamant, N.; Missarova, A.; Wang, H.; Hao, M.; Bravo, H. C.; Scalia, G.; Regev, A.; Heimberg, G.
10.1101/2024.11.18.624166 — bioinformatics — Posted on 2024-11-20
1663 Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet
Hoffman, G. E.; Lee, D.; Bendl, J.; Fnu, P.; Hong, A.; Casey, C.; Alvia, M.; Shao, Z.; Argyriou, S.; Therrien, K.; Venkatesh, S.; Voloudakis, G.; Haroutunian, V.; Fullard, J. F.; Roussos, P.
10.1101/2023.03.17.533005 — genomics — Posted on 2024-11-20
1665 Modeling Compound Lipid Homeostasis Using Stable Isotope Tracing
Wessendorf-Rodriguez, K.; Ruchhoeft, M. L.; Ashley, E. L.; Galvez, H. M.; Murray, C. W.; Huang, Y.; Mcgregor, G. H.; Kambhampati, S.; Shaw, R. J.; Metallo, C. M.
10.1101/2024.10.16.618599 — cell biology — Posted on 2024-11-20
1666 Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
Cozzolino, K.; Sanford, L.; Hunter, S.; Molison, K.; Erickson, B.; Courvan, M. C. S.; Jones, T.; Ajit, D.; Galbraith, M. D.; Espinosa, J. M.; Bentley, D. L.; Allen, M. A.; Dowell, R. D. A.; Taatjes, D. J.
10.1101/2023.07.05.547813 — molecular biology — Posted on 2024-11-20
1667 An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion.
Sharma, P.; Guo, A.; Boada Romero, E.; Poudel, S.; Verbist, K. C.; Palacios, G.; Immadisetty, K.; Chen, M. J.; Haydar, D.; Mishra, A.; Peng, J.; Babu, M. M.; Krenciute, G.; Glazer, E. S.; Green, D. R.
10.1101/2024.05.09.593421 — immunology — Posted on 2024-11-20
1668 Orthogonal spectral and temporal envelope representation in auditory cortex
Takahashi, K.; Guo, T.; Yamagishi, T.; Ohshima, S.; Tsukano, H.; Horii, A.
10.1101/2024.10.28.620417 — neuroscience — Posted on 2024-11-20
1669 MYB68 regulates radial endodermal differentiation and suberin patterning
Kraska, L.; Molina, D.; Nakano, R. T.; Ragni, L.; Andersen, T. G.; Jordan, P. F.; Mercadal, J.
10.1101/2024.05.09.593291 — plant biology — Posted on 2024-11-20
1670 Bacteria in honeybee crops are decoupled from those in floral nectar and bee mouths
Warren, M. L.; Tsuji, K.; Decker, L. E.; Kishi, M.; Yang, J.; Howe, A. C.; Fukami, T.
10.1101/2024.03.01.583024 — ecology — Posted on 2024-11-20
1671 Molecular dynamics of the matrisome across sea anemone life history
Bergheim, B. G.; Cole, A. G.; Rettel, M.; Stein, F.; Redl, S.; Hess, M. W.; Ikmi, A.; Özbek, S.
10.1101/2024.10.29.620203 — developmental biology — Posted on 2024-11-20
1675 Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice
Goldin, K.; van Tol, S.; Johnson, R. C.; Mukesh, R. K.; Gallogly, S.; Schulz, J. E.; Prado-Smith, J.; Saturday, G.; Yinda, K. C.; Munster, V. J.; de Wit, E.; van Doremalen, N.
10.1101/2024.11.19.624162 — microbiology — Posted on 2024-11-20
1678 In silico analysis of the evolution of root phenotypes during maize domestication in Neolithic soils of Tehuacan
Lopez-Valdivia, I.; Vallebueno-Estrada, M.; Rangarajan, H.; Swarts, K.; Benz, B.; Blake, M.; Sidhu, J. S.; Perez-Limon, S.; Sawers, R. J.; Schneider, H.; Lynch, J.
10.1101/2024.11.18.623787 — plant biology — Posted on 2024-11-20
1679 Longitudinal Microbiome-based Interpretable Machine Learning for Identification of Time-Varying Biomarkers in Early Prediction of Disease Outcomes
Dai, Y.; Qian, Y.; Qu, Y.; Guan, W.; Xie, J.; Wang, D.; Butler, C.; Dashper, S.; Carroll, I.; Divaris, K.; Liu, Y.; Wu, D.
10.1101/2024.10.18.619118 — bioinformatics — Posted on 2024-11-20
1680 AZIN2-dependent polyamine metabolism determines adipocyte progenitor fate and protects against obesity and dysmetabolism
Mund, C.; Sinha, A.; Aderhold, A.; Mateska, I.; Hagag, E.; Traikov, S.; Gercken, B.; Soto, A.; Pollock, J.; Arndt, L.; Woelk, M.; Werner, N.; Fodelianaki, G.; Subramanian, P.; Chung, K.-J.; Grossklaus, S.; Langner, M.; Elgendy, M.; Grinenko, T.; Wielockx, B.; Dahl, A.; Gericke, M.; Blueher, M.; Coskun, U.; Voehringer, D.; Fedorova, M.; Peitzsch, M.; Murray, P. J.; Chavakis, T.; Alexaki, V. I.
10.1101/2024.11.19.621837 — cell biology — Posted on 2024-11-20
1681 Arginine Regulates the Mucoid Phenotype of Hypervirulent Klebsiella pneumoniae
Ring, B. E.; Shepard, G. E.; Khadka, S.; Holmes, C. L.; Bachman, M. A.; Mike, L. A.
10.1101/2024.11.20.624485 — microbiology — Posted on 2024-11-20
1682 Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro
Gonzales-Huerta, L. E.; Williams, T. J.; Aljohani, R.; Evans, C.; Robertson, B. D.; Armstrong-James, D.
10.1101/2024.11.18.623945 — immunology — Posted on 2024-11-20
1683 Sensing the shape of a surface by intracellular filaments
Shi, H.; Nguyen, J.; Gitai, Z.; Shaevitz, J. W.; Bratton, B. P.; Gopinathan, A.; Grason, G.; Huang, K. C.
10.1101/2024.11.18.624198 — biophysics — Posted on 2024-11-20
1684 Progressive chromosome shape changes during cell divisions, recapitulated by loop capture simulations
Kakui, Y.; Kusano, Y.; Clarence, T.; Lopez, M.; Hirota, T.; Khatri, B. S.; Uhlmann, F.
10.1101/2024.11.19.623756 — biophysics — Posted on 2024-11-20
1686 Modifying the aggregation state may improve the activity of Ozempic
Bolano Alvarez, A.; Bjerring, P.; Bakke Arvesen, K.; Fjellhaugen Hjuler, K.; Petersen, S. B.
10.1101/2024.11.19.624403 — biophysics — Posted on 2024-11-20
1687 Boltz-1: Democratizing Biomolecular Interaction Modeling
Wohlwend, J.; Corso, G.; Passaro, S.; Reveiz, M.; Leidal, K.; Swiderski, W.; Portnoi, T.; Chinn, I.; Silterra, J.; Jaakkola, T.; Barzilay, R.
10.1101/2024.11.19.624167 — biophysics — Posted on 2024-11-20
1690 Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth
Funk, A. L.; Katerji, M.; Afifi, M.; Nyswaner, K.; Woodroofe, C. C.; Edwards, Z. C.; Lindberg, E.; Bergman, K. L.; Gough, N. R.; Rubin, M. R.; Karpinska, K.; Trotter, E. W.; Dash, S.; Ries, A. L.; James, A.; Robinson, C. M.; Difilippantonio, S.; Karim, B. O.; Chang, T. C.; Chen, L.; Xu, X.; Doroshow, J.; Ahel, I.; Marusiak, A.; Swenson, R. E.; Cappell, S. D.; Brognard, J.
10.1101/2024.11.19.623840 — cancer biology — Posted on 2024-11-20
1691 SuperWater: Predicting Water Molecule Positions on Protein Structures by Generative AI
Kuang, X.; su, z.; Liu, Y.; Lin, X.; Smith, J. S.; Derr, T.; Wu, Y.; Meiler, J.
10.1101/2024.11.18.624208 — bioinformatics — Posted on 2024-11-20
1692 Evaluating discordant somatic calls across mutation discovery approaches to minimize false negative drug-resistant findings
Lin, H.-F.; Chien, P.-M.; Cheng, C.; Yuan, T.-H.; Wang, Y.-B.; Chen, P.-L.; Chen, C.-Y.; Huang, J.-H.; Hsu, J. S.
10.1101/2023.10.26.562640 — bioinformatics — Posted on 2024-11-20
1695 Targeted detection of endogenous LINE-1 proteins and ORF2p interactions
Nielsen, M. I.; Wolters, J. C.; Rosas Bringas, O. G.; Jiang, H.; Di Stefano, L. H.; Oghbaie, M.; Hozeifi, S.; Nitert, M. J.; van Pijkeren, A.; Smit, M.; ter Morsche, L.; Mourtzinos, A.; Deshpande, V.; Taylor, M. S.; LaCava, J.
10.1101/2024.11.20.624490 — molecular biology — Posted on 2024-11-20
1696 Transcriptomic profiling of gill biopsies to define predictive markers for seawater survival in farmed Atlantic salmon
Gronvold, L.; Dalum, M. J.; Striberny, A.; Manousi, D.; Ytrestoyl, T.; Morkore, T.; Boison, S.; Gjerde, B.; Jorgensen, E.; Sandve, S. R.; Hazlerigg, D.
10.1101/2024.08.20.608748 — genomics — Posted on 2024-11-20
1698 The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelity.
Walker, A.; Lanz, A.; Jamshad, M.; Garvin, A. J.; Wotherspoon, P.; Cooper, B. F.; Knowles, T. J.; Morris, J. R.
10.1101/2022.03.18.484840 — molecular biology — Posted on 2024-11-20
1699 N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs
Lee, E. S.; Smith, H. W.; Wang, Y. E.; Ihn, S. S.; Scalize de Olivera, L.; Kejiou, N. S.; Liang, Y. L.; Nabeel-Shah, S.; Jomphe, R. Y.; Pu, S.; Greenblatt, J. F.; Palazzo, A. F.
10.1101/2023.06.20.545713 — molecular biology — Posted on 2024-11-20
1702 Neurostructural and cognitive signatures of novel polygenic risk scores for molecular brain aging
Clifford, K. P.; Dos Santos, F.; Abdelhack, M.; Felsky, D.; Sibille, E.; Nikolova, Y.
10.1101/2024.11.17.624029 — neuroscience — Posted on 2024-11-20
1703 Statistical learning beyond words in human neonates
Flo, A.; Benjamin, L.; Palu, M.; Dehaene-Lambertz, G.
10.1101/2024.07.26.605295 — neuroscience — Posted on 2024-11-20
1705 Evaluation of gene expression-based predictors of lymph node metastasis in bladder cancer
Johansson, H. B.; Liedberg, F.; Bernardo, C.; Zadoroznyj, A.; Höglund, M.; Eriksson, P.; Sjödahl, G.
10.1101/2024.11.19.623582 — cancer biology — Posted on 2024-11-20
1706 The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim
Hammond, C. V.; Williams, S. T.; Vega, M. M.; Ao, D.; Li, G.; Salati, R. M.; Pariser, K. M.; Shourijeh, M. S.; Habib, A. W.; Patten, C.; Fregly, B. J.
10.1101/2024.10.30.620965 — bioengineering — Posted on 2024-11-20
1708 Whole-Genome Sequencing of the Wild Barley Diversity Collection: A Resource for Identifying and Exploiting Genetic Variation for Cultivated Barley Improvement
Sallam, A. H.; Guo, Y.; Jayakodi, M.; Himmelbach, A.; Fiebig, A.; Simmons, J.; Bethke, G.; Lee, Y.; Spanner, R.; Badea, A.; Baum, M.; Belzile, F.; Ben-David, R.; Brueggeman, R.; Case, A.; Cattivelli, L.; Davis, M.; Dockter, C.; Dolezel, J.; Dreiseitl, A.; Gavin, R.; Glick, L.; Greiner, S.; Hamilton, R.; Hayes, P. M.; Heisel, S.; Henson, C.; Kilian, B.; Komatsuda, T.; Li, C.; Liu, C.; Mahalingam, R.; Maruschewski, M.; Matny, O.; Maurer, A.; Mayer, K. F. X.; Mayrose, I.; Morrell, P.; Moscou, M.; Muehlbauer, G. J.; Oono, Y.; Ordon, F.; Ozkan, H.; Pecinka, A.; Perovic, D.; Pillen, K.; Pourkheirand
10.1101/2024.11.18.624148 — genomics — Posted on 2024-11-20
1709 Global diversity and evolution of Salmonella Panama, an understudied serovar causing gastrointestinal and invasive disease worldwide: a genomic epidemiology study
Pulford, C. V.; Perez-Sepulveda, B. M.; Ingle, D. J.; Bengtsson, R. J.; Bennet, R. J.; Rodwell, E. V.; Pardos de la Gandara, M.; Chong, C.; De Silva, P. M.; Ravel, M.; Guibert, V.; Njamkepo, E.; Hall, N.; Chattaway, M. A.; Howden, B.; Williamson, D. A.; Hinton, J. C. D.; Weill, F.-X.; Baker, K. S.
10.1101/2024.02.09.579599 — genomics — Posted on 2024-11-20
1710 Divergent C. elegans toxin alleles are suppressed by distinct mechanisms
Zdraljevic, S.; Walter-McNeill, L.; Bruni, G.; Marquez, H.; Collins, J.; Leighton, D. H. W.; Alexander, N.; Bloom, J. S.; Kruglyak, L.
10.1101/2024.04.26.591160 — evolutionary biology — Posted on 2024-11-20
1714 Signal transduction pathways controlling Ins2 gene activity and β cell state transitions
Chu, J.; Sabbineni, B.; Cen, H. H.; Hu, X.; Sun, W. G.; Brownrigg, G. P.; Xia, Y. H.; Rogalski, J.; Johnson, J. D.
10.1101/2024.06.06.597838 — cell biology — Posted on 2024-11-20
1715 High confidence glycosomal membrane protein inventory unveils trypanosomal Peroxin PEX15
Krishna, C. K.; Das, H.; Hohnen, L.; Schliebs, W.; Oeljeklaus, S.; Warscheid, B.; Kalel, V. C.; Erdmann, R.
10.1101/2023.10.13.562043 — cell biology — Posted on 2024-11-20
1716 Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators
Bonilla, G.; Morris, A.; Kundu, S.; Ducasse, A.; Kirkpatrick, G.; Jeffries, N. E.; Chetal, K.; Yvanovich, E. E.; Milosevic, J.; Zhao, T.; Xia, J.; Barghout, R.; Scadden, D.; Mansour, M.; Kingston, R. E.; Sykes, D. B.; Mercier, F. E.; Sadreyev, R. I.
10.1101/2024.02.29.582846 — molecular biology — Posted on 2024-11-20
1718 CetZ1-dependent polar assembly of the motility machinery in haloarchaea
Brown, H. J.; Islam, M. I.; Ruan, J.; Baker, M. A.; Ithurbide, S.; Duggin, I. G.
10.1101/2024.05.02.592137 — microbiology — Posted on 2024-11-20
1719 Direct thin-layer agar for bedaquiline-susceptibility testing of Mycobacterium tuberculosis at BSL2 level yields high accuracy in 15 days from sputum processing.
Cuella Martin, I.; Runyambo, D.; De Bock, S.; Diels, M.; Niyompano, H.; Hakizayezu, F.; Keysers, J.; de Rijk, W. B.; Habimana, Y. M.; Gahamanyi, N.; Ardizzoni, E.; Muvunyi, C. M.; de Jong, B.; Semuto Ngabonziza, J.-C.; Rigouts, L.
10.1101/2024.11.18.624108 — microbiology — Posted on 2024-11-20
1720 Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum
Evseeva, D.; Pecrix, Y.; Kucka, M.; Weiler, C.; Franzl, C.; Vlkova-Zlebkova, M.; Colombi, E.; Chan, Y. F.; Poussier, S.; Wicker, E.; McCann, H. C.
10.1101/2024.10.16.618685 — microbiology — Posted on 2024-11-20
1722 Antagonism as a foraging strategy in microbial communities
Stubbusch, A. K. M.; Peaudecerf, F. J.; Soo Lee, K.; Paoli, L.; Schwartzman, J.; Stocker, R.; Basler, M.; Schubert, O. T.; Ackermann, M.; Magnabosco, C.; D'Souza, G. G.
10.1101/2024.11.04.621785 — microbiology — Posted on 2024-11-20
1723 Structure-Guided Loop Grafting Improves Expression and Stability of Influenza Neuraminidase for Vaccine Development
Rijal, P.; Wei, L.; Paesen, G. C.; Stuart, D. I.; Howarth, M. R.; Huang, K.-Y. A.; Bowden, T. A.; Townsend, A. R.
10.1101/2024.10.11.617814 — immunology — Posted on 2024-11-20
1724 Lymph node fibroblast phenotypes and immune crosstalk regulated by Podoplanin activity
Makris, S.; Hari-Gupta, Y.; Cantoral-Rebordinos, J. A.; Martinez, V. G.; Horsnell, H. L.; Benjamin, A.; Cinti, I.; Shewring, D.; Nguyen, N.; Jovancheva, M.; de Winde, C. M.; Denton, A.; Acton, S. E.
10.1101/2022.12.01.518753 — immunology — Posted on 2024-11-20
1727 MRI R2* captures inflammation in disconnected brain structures after stroke: a translational study
Koubiyr, I.; Yamamoto, T.; Petit, L.; Dubourdieu, N.; Avignone, E.; Cozensa, E.; Galmiche, C.; Fukutomi, H.; Sibon, I.; Dousset, V.; Thiebaut de Schotten, M.; Panatier, A.; Tible, M.; Tourdias, T.
10.1101/2024.11.18.624105 — neuroscience — Posted on 2024-11-20
1730 A framework for target discovery in rare cancers
Li, B.; Sadagopan, A.; Li, J.; Wu, Y.; Cui, Y.; Weiss, C.; Konda, P.; Choueiri, T.; Doench, J.; Viswanathan, S.
10.1101/2024.10.24.620074 — cancer biology — Posted on 2024-11-20
1731 AI-readiness for Biomedical Data: Bridge2AI Recommendations
Clark, T.; Caufield, H.; Parker, J. A.; Al Manir, S.; Amorim, E.; Eddy, J.; Gim, N.; Gow, B.; Goar, W.; Haendel, M.; Hansen, J. N.; Harris, N.; Hermjakob, H.; McWeeney, S. K.; Nebeker, C.; Nikolov, M.; Shaffer, J.; Sheffield, N.; Sheynkman, G.; Stevenson, J.; Mungall, C.; Chen, J. Y.; Wagner, A.; Kong, S. W.; Ghosh, S. S.; Patel, B.; Williams, A.; Munoz-Torres, M. C.
10.1101/2024.10.23.619844 — bioinformatics — Posted on 2024-11-20
1732 Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure
Kim, S.; Kim, Y. K.; Kim, S.; Choi, Y.-S.; Lee, I.; Joo, H.; Kim, J.; Kwon, M.; Park, S.; Jo, M. K.; Choi, Y.; D'Souza, T.; Jung, J. W.; Zakhem, E.; Lenzini, S.; Woo, J.; Choi, H.; Park, J.; Park, S.-Y.; Kim, G. B.; Nam, G.-H.; Kim, I.-S.
10.1101/2024.05.24.592430 — bioengineering — Posted on 2024-11-20
1733 Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking
Thawani, A.; Rodriguez-Vargas, A.; Treeck, B. V.; Hassan, N. T.; Adelson, D. L.; Nogales, E.; Collins, K.
10.1101/2024.11.11.623112 — biochemistry — Posted on 2024-11-20
1735 Viral susceptibility and innate immune competency of Carollia perspicillata bat cells produced for virological studies
Gonzalez, V.; Word, C.; Guerra-Pilaquinga, N.; Mazinani, M.; Fawcett, S.; Portfors, C.; Falzarano, D. C.; Kell, A. M.; Jangra, R. K.; Banerjee, A.; Seifert, S. N.; Letko, M. C.
10.1101/2024.11.19.624190 — microbiology — Posted on 2024-11-19
1737 Towards optimizing diversifying base editors for high-throughput studies of single-nucleotide variants
Schwartz, C. I.; Abell, N. S.; Li, A.; Aradhana, F.; Tycko, J.; Truong, A.; Montgomery, S. B.; Hess, G. T.
10.1101/2024.11.18.621003 — genomics — Posted on 2024-11-19
1738 Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos
Hou, Y.; Nie, Z.; Jiang, Q.; Velychko, S.; Heising, S.; Bedzhov, I.; Wu, G.; Adachi, K.; Schöler, H. R.
10.1101/2023.10.18.562912 — developmental biology — Posted on 2024-11-20
1742 Endothelial Rho kinase controls blood vessel integrity and angiogenesis
Lange, M.; Francis, C.; Furtado, J.; Kim, Y.-B.; Liao, J. K.; Eichmann, A.
10.1101/2024.11.19.624343 — developmental biology — Posted on 2024-11-19
1744 eDNA replicates, polymerase and amplicon size impact inference of richness across habitats
Anmarkrud, J. A.; dos Anjos Santa Rosa, F.; Thorbek, L.; Schroder-Nielsen, A.; Melo Sviggum, S.; Ready, J. S.; de Boer, H.; Mauvisseau, Q.
10.1101/2024.11.19.624235 — molecular biology — Posted on 2024-11-19
1745 Berberine: A dual anti-HIV and anti- cervical cancer compound
Naushad, W.; Okeoma, B. C.; Islam, H. K.; Wang, Z. Z.; Yang, N.; Li, X.-M.; Okeoma, C. M.
10.1101/2024.11.18.624212 — molecular biology — Posted on 2024-11-19
1746 A highly conserved sRNA downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of Bordetella pertussis
Sim, M.; Nguyen, J.; Skopova, K.; Yoo, K.; Tai, C.-H.; Knipling, L.; Chen, Q.; Kim, D.; Nolan, S.; Elaksher, R.; Majdalani, N.; Lorenzi, H.; Stibitz, S.; Moon, K.; Hinton, D. M.
10.1101/2024.11.19.624354 — microbiology — Posted on 2024-11-19
1747 An antibiotic-free antimicrobial combination of bacteriocins and a peptidoglycan hydrolase: in vitro and in vivo assessment of its efficacy
Kranjec, C.; Oftedal, T. F.; Ovchinnikov, K. V.; da Silva Duarte, V.; Hermansen, S.; Kaus-Drobek, M.; Sabala, I.; Porcellato, D.; Carlsen, H.; Kjos, M.
10.1101/2024.11.19.624290 — microbiology — Posted on 2024-11-19
1749 Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice
Goldin, K.; van Tol, S.; Johnson, R. C.; Mukesh, R. K.; Gallogly, S.; Schulz, J. E.; Saturday, G.; Yinda, K. C.; Munster, V. J.; de Wit, E.; van Doremalen, N.
10.1101/2024.11.19.624162 — microbiology — Posted on 2024-11-19
1751 Low levels of neutralizing antibodies against SARS-CoV-2 KP.3.1.1 and XEC in serum from seniors in May 2024
Fossum, E.; Vikse, E. L.; Robertson, A. H.; Wolf, A.-S.; Rohringer, A.; Trogstad, L.; Mjaaland, S.; Hungnes, O.; Bragstad, K.
10.1101/2024.11.18.623742 — immunology — Posted on 2024-11-19
1752 Early-Life Immune Activation Shapes Microglial Responses and Reduces Abeta Pathology in 5xFAD mice
Yang, Y.; Garcia-Cruzado, M.; Zeng, H.; Wang, X.; Bachiller, S.; Camprubi-Ferrer, L.; Bahatyrevich-Kharitonik, B.; Fernandez-Calle, R.; Deierborg, T.
10.1101/2024.11.19.624204 — neuroscience — Posted on 2024-11-19
1753 Anatomical characterisation of somatostatin-expressing neurons belonging to the anterolateral system
Ma, W.; Polgar, E.; Dickie, A. C.; Hajer, M. A.; Quillet, R.; Gutierrez-Mecinas, M.; Yadav, M.; Hachisuka, J.; Todd, A. J.; Bell, A. M.
10.1101/2024.11.19.624289 — neuroscience — Posted on 2024-11-19
1754 Development of a p62 biodegrader for autophagy targeted degradation
Thiel, Z.; Marcellin, D.; Manneville, C.; Goretzki, B.; Egger, L.; Maher, R.; Siccardi, N.; Sansig, G.; Torres, L.; Probst, A.; Mueller, C. S.; George, N.; Vogel, M.; Sinterhauf, S.; Lavoisier, A.; Choi, J.-Y.; Forcellino, L.; Hauck, P.; Be, C.; Villard, F.; Gutmann, S.; Meyer, M.; Freuler, F.; Patoor, M.; Mitchell, G.; Nyfeler, B.
10.1101/2024.11.19.624312 — synthetic biology — Posted on 2024-11-19
1757 Spatially Resolved in vivo CRISPR Screen Sequencing via Perturb-DBiT
Baysoy, A.; Tian, X.; Zhang, F.; Renauer, P.; Bai, Z.; Shi, H.; Li, H.; Tao, B.; Yang, M.; Enninful, A.; Gao, F.; Wang, G.; Zhang, W.; Tran, T.; Patterson, N. H.; Bao, S.; Dong, C.; Xin, S.; Zhong, M.; Rankin, S.; Guy, C.; Wang, Y.; Connelly, J. P.; Pruett-Miller, S. M.; Chi, H.; Chen, S.; Fan, R.
10.1101/2024.11.18.624106 — genomics — Posted on 2024-11-19
1758 Critical assessment of nanopore sequencing for the detection of multiple forms of DNA modifications
Kong, Y.; Zhang, Y.; Mead, E. A.; Chen, H.; Loo, C. E.; Fan, Y.; Ni, M.; Zhang, X.-S.; Kohli, R.; Fang, G.
10.1101/2024.11.19.624260 — genomics — Posted on 2024-11-19
1759 RNA editing is a molecular clock in unmodified human cells
Ghareeb, A. E.; Bayne, J.; Wagen, A. Z.; Abdelhafid, A. M.; Miller, D.; Cubitt, L.; Meran, L.; Hill, C.; Cribbs, A. P.; Ryten, M.; Gandhi, S.; Gaffney, E.; Coles, M.; Young, G.; Rodriques, S. G.
10.1101/2024.11.18.624170 — genomics — Posted on 2024-11-19
1760 Comparative single-cell lineage bias in human and murine hematopoietic stem cells
Shamie, I.; Bliss-Moreau, M.; Lee, J. C.; Mathieu, R.; Hoffman, H. M.; Geng, B.; Lewis, N. E.; Zhu, Y. P.; Croker, B. A.
10.1101/2024.11.19.624262 — genomics — Posted on 2024-11-19
1761 The White Sea littoral oligochaete Lumbricillus sp. as a model for annelid development studies
Matveicheva, E. P.; Neretina, T. V.; Ekimova, I. A.; Konduktorova, V. V.; Semenova, M. L.; Nikishin, D. A.
10.1101/2024.11.19.624369 — developmental biology — Posted on 2024-11-19
1762 HUMAN SPINAL CORD ORGANOIDS REVEAL CELL INTERCALATION AS A CONSERVED MECHANISM FOR SECONDARY NEURULATION
Blanco-Ameijeiras, J.; Garcia-Valero, M.; El Majzoub, Y.; Rebollo, E.; Macho-Rendon, J.; Corbacho, J.; Martinez-Morales, J. R.; Marti, E.
10.1101/2024.11.19.624296 — developmental biology — Posted on 2024-11-19
1764 The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiation
Piscitelli, S.; Cascone, E.; D'Ambrosio, C.; Divisato, G.; De Lisio, L.; Leoni, G.; Matassa, D. S.; Lanzuolo, C.; Rosti, V.; Zizolfi, M. C.; Matuozzo, M.; di Patrizio Soldateschi, E.; Maiuri, P.; Scaloni, A.; Passaro, F.; Parisi, S.
10.1101/2024.11.19.624261 — molecular biology — Posted on 2024-11-19
1768 Gut Microbiota and Derived Metabolites Mediate Obstructive Sleep Apnea Induced Atherosclerosis
Xue, J.; Allaband, C.; Zuffa, S.; Poulsen, O.; Meadows, J.; Zhou, D.; Dorrestein, P. C.; Knight, R.; Haddad, G. G.
10.1101/2024.11.18.624205 — microbiology — Posted on 2024-11-19
1769 Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals
Zielinska, K.; Michalowska-Sawczyn, M.; Kosciolek, T.; Labaj, P.; Bicakci, B.; Cieszczyk, P.; Kochanowicz, A.; Mieszkowski, J.; Huminska-Lisowska, K.
10.1101/2024.11.19.624295 — microbiology — Posted on 2024-11-19
1770 In vivo CRISPR screens identify key modifiers of CAR T cell function in myeloma
Korell, F.; Knudsen, N. H.; Kienka, T.; Escobar, G.; Nobrega, C.; Anderson, S.; Cheng, A. Y.; Zschummel, M.; Bouffard, A.; Kann, M. C.; Goncalves, S.; Pope, H. W.; Pezeshki, M.; Rojas, A.; Suermondt, J. S. M. T.; Phillips, M.; Berger, T. R.; Park, S.; Salas-Benito, D.; Darnell, E. P.; Birocchi, F.; Leick, M. B.; Larson, R. C.; Doench, J. G.; Sen, D.; Yates, K. B.; Manguso, R. T.; Maus, M. V.
10.1101/2024.11.19.624352 — immunology — Posted on 2024-11-19
1772 Global and selective effects of auditory attention on arousal: insights from pupil dilation
Grandjean, A.; Hoyer, R. S.; Mathieu, A.; Caclin, A.; Moulin, A.; Bidet-Caulet, A.
10.1101/2024.11.19.624303 — neuroscience — Posted on 2024-11-19
1779 A novel mouse model for developmental and epileptic encephalopathy by Purkinje cell-specific deletion of Scn1b
Guillen, F. I.; Geist, M. A.; Cheng, S.-Y.; Harris, A. M.; Trevino, M. E.; Brumback, A. C.; Nishiyama, H.; Howard, M. A.
10.1101/2024.11.19.624370 — neuroscience — Posted on 2024-11-19
1781 Temporal expectations modulate coupling between frontal and sensory brain areas
Nagy, P.; Kovacs, P.; Boncz, A.; Szalardy, O.; Baumgartner, R.; Ignatiadis, K.; Winkler, I.; Toth, B.
10.1101/2024.11.19.624242 — neuroscience — Posted on 2024-11-19
1782 A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation
Wang, Y.; Zhang, Y.; Leung, V.; Heydari-Seradj, S.; Sonmez, U.; Servin-Vences, R.; Lipomi, D. J.; Ye, L.; Patapoutian, A.
10.1101/2024.11.18.624210 — neuroscience — Posted on 2024-11-19
1784 Uncertainty mapping and probabilistic tractography using Simulation-Based Inference in diffusion MRI: A comparison with classical Bayes
Manzano-Patron, J. P.; Deistler, M.; Schröder, C.; Kypraios, T.; Goncalves, P. J.; Macke, J. H.; Sotiropoulos, S. S. N.
10.1101/2024.11.19.624267 — neuroscience — Posted on 2024-11-19
1787 Scalable cell-free production of active T7 RNA polymerase
Rezvani, R. N.; Aw, R.; Chan, W.; Satish, K.; Chen, H.; Lavy, A.; Rimal, S.; Patel, D. A.; Kvam, E.; Karim, A. S.; Krüger, A.; Kightlinger, W. K.; Jewett, M. C.
10.1101/2024.11.19.623967 — synthetic biology — Posted on 2024-11-19
1789 Id1 Promotes Clonal Hematopoiesis in Mice with Tet2 Loss of Function
Singh, S.; Sarkar, T.; Gudmundsson, K. O.; Jakubison, B. L.; Morris, H. M.; Burkett, S.; Baktiar, K.; Pauly, G. T.; Sigano, D. M.; Schneider, J. P.; Keller, J. R.
10.1101/2024.11.19.624318 — cancer biology — Posted on 2024-11-19
1790 Spatio-temporal T cell tracking for personalized TCR-T designs in childhood cancer
Sentis, I.; Melero, J. L.; Cebria, A.; Grzelak, M.; Soto, M.; Michel, A.; Rovira, Q.; Rodriguez-Hernandez, C. J.; Caratu, G.; Urpi-Badell, A.; Sauvage, C.; Mendizabal-Sasieta, A.; Maspero, D.; Pascual-Reguant, A.; Munoz-Perez, J. P.; Mora, J.; Harari, A.; Nieto, J. C.; Avgustinova, A.; Heyn, H.
10.1101/2024.11.18.624071 — genomics — Posted on 2024-11-19
1793 The evolutionary path of the epithelial sodium channel delta-subunit in Cetartiodactyla points to a role in sodium sensing
Zahnow, F.; Jaeger, C.; Mohamed, Y.; Vogelhuber, G.; May, F.; Ciocan, A. M.; Manieri, A.; Maxeiner, S.; Krasteva-Christ, G.; Cobain, M. R. D.; Podsiadlowski, L.; Crespo-Picazo, J. L.; Garcia-Parraga, D.; Althaus, M.
10.1101/2024.11.18.623996 — evolutionary biology — Posted on 2024-11-19
1794 Detecting interspecific positive selection using convolutional neural networks
West, C.; Walker, C. R.; Arasti, S.; Vasilev, V.; Xu, X.; De Maio, N.; Goldman, N.
10.1101/2024.11.18.624117 — evolutionary biology — Posted on 2024-11-19
1797 GLOBAL BIOGEOGRAPHY AND EVOLUTIONARY DRIVERS OF FERNS WITH CHLOROPHYLLOUS SPORES
Mellado-Mansilla, D.; Weigelt, P.; Kessler, M.; Craven, D.; Zotz, G.; Kreft, H.
10.1101/2024.11.18.624067 — ecology — Posted on 2024-11-19
1800 IFN-associated B cell hyperactivity is highly enriched in SLE patients harboring Sm/RNP antibodies
Van Dooren, H. J.; Atisha-Fregoso, Y.; Dorjee, A. L.; Huizinga, T. W. J.; Mackay, M.; Aranow, C.; Toes, R. E. M.; Diamond, B.; Suurmond, J.
10.1101/2024.11.18.624119 — immunology — Posted on 2024-11-19
1805 Innovative mutant screening identifies TRANSPARENT TESTA7 as a player in seed oil/protein partitioning
Lecureuil, A.; Corso, M.; Boutet, S.; Le-Gall, S.; Ninoles, R.; Gadea, J.; Guerche, P.; Jasinski, S.
10.1101/2024.11.18.624101 — plant biology — Posted on 2024-11-19
1806 In silico analysis of the evolution of root phenotypes during maize domestication in Neolithic soils of Tehuacan
Lopez-Valdivia, I.; Vallebueno-Estrada, M.; Rangarajan, H.; Swarts, K.; Benz, B.; Blake, M.; Sidhu, J. S.; Perez-Limon, S.; Sawers, R. J.; Schneider, H.; Lynch, J.
10.1101/2024.11.18.623787 — plant biology — Posted on 2024-11-19
1808 A histomorphological atlas of resected mesothelioma from 3446 whole-slide images discovered by self-supervised learning
Seyedshahi, F.; Rakovic, K.; Poulain, N.; Quiros, A. C.; Powley, I. R.; Klebe, S.; Richards, C.; Uraiby, H.; Nakas, A.; Wilson, C.; Sereno, M.; Officer-Jones, L.; Ficken, C.; Teodosio, A.; Ballantyne, F.; Murphy, D.; Yuan, K.; Le Quesne, J.
10.1101/2024.11.18.624103 — pathology — Posted on 2024-11-19
1809 Single cell analysis of Barrett's esophagus and carcinoma reveals cell types conferring risk via genetic predisposition
Wenzel, M. C.; Giel, A.-S.; Plum, P. S.; Hoppe, S.; Franitza, M.; Jonas, C.; Dasmeh, P.; Thieme, R.; Zhao, Y.; Heider, D.; Palles, C.; Fitzgerald, R. C.; Bruns, C. J.; Buettner, R.; Quaas, A.; Gockel, I.; Maj, C.; Chon, S.-H.; Schumacher, J.; Hillmer, A. M.
10.1101/2024.11.18.624112 — cancer biology — Posted on 2024-11-19
1811 Preclinical Evaluation of PTK7-Targeted Radionuclide Therapy
Lindland, K.; Westrom, S.; Dragovic, S. M.; Li, R. G.; Malenge, M. M.; Ho, B.; Juzeniene, A.; Bonsdorff, T. B.
10.1101/2024.11.18.624082 — cancer biology — Posted on 2024-11-19
1812 Integrated Ising Model with global inhibition for decision making
Tapinova, O.; Finkelman, T.; Reitich-Stolero, T.; Paz, R.; Tal, A.; Gov, N.
10.1101/2024.11.18.624088 — biophysics — Posted on 2024-11-19
1814 Divergent effects of pathological α-synuclein truncations and mutations on phase separation
Ray, S.; Chiodaroli, C.; Farzadfard, A.; Kunka, A.; Schott, K. H.; Hertel, S.; Mojtic, K.; Klausen, L. K.; Galvagnion, C.; Buell, A. K.
10.1101/2024.11.18.624073 — biophysics — Posted on 2024-11-19
1815 A synthetic potassium channel reduces oxidative stress 1 via cellular adaptronics
Russo, A.; Saponaro, A.; Trini, S.; Nelson, T. S.; Allen, H. N.; Oddone, R.; Villa, C.; Torrente, Y.; Khanna, R.; Porro, A.; Thiel, G.; Moroni, A.
10.1101/2024.11.18.624138 — biophysics — Posted on 2024-11-19
1818 Repeated behavioral evolution is associated with targeted convergence of gene expression in cavity-nesting songbirds
Lipshutz, S. E.; Hibbins, M. S.; Bentz, A. B.; Buechlin, A. M.; Empson, T. A.; George, E. M.; Hauber, M. E.; Rusch, D. B.; Schelsky, W. M.; Thomas, Q. K.; Torneo, S. J.; Turner, A. M.; Wolf, S. E.; Woodruff, M. J.; Hahn, M. W.; Rosvall, K. A.
10.1101/2024.02.13.580205 — evolutionary biology — Posted on 2024-11-19
1819 An animal model for autoinflammation with infantile enterocolitis
Wang, Y.; Gao, J. Z.; Gurung, P.; Short, S. P.; Xiong, Y.; Kang, Z.
10.1101/2024.11.16.623944 — immunology — Posted on 2024-11-19
1821 A near-tight lower bound on the density of forward sampling schemes
Kille, B.; Groot Koerkamp, R.; McAdams, D.; Liu, A.; Treangen, T.
10.1101/2024.09.06.611668 — bioinformatics — Posted on 2024-11-19
1824 A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting
Birtwistle, M. R.; Huggins, J. R.; Zadeh, C. O.; Sarmah, D.; Srikanth, S.; Jones, B. K.; Cascio, L. N.; Dean, D. R.
10.1101/2024.05.10.593650 — biochemistry — Posted on 2024-11-19
1827 Live-imaging reveals Coordinated Cell Migration and Cardiac Fate Determination during Mammalian Gastrulation.
Abukar, S.; Embacher, P.; Cicarrelli, A.; Varsani-Brown, S.; North, I. G. W.; Dean, J. A.; Briscoe, J.; Ivanovitch, k.
10.1101/2023.12.19.572445 — developmental biology — Posted on 2024-11-19
1828 Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
Lam, B.; Kajderowicz, K. M.; Keys, H. R.; Roessler, J. M.; Frenkel, E. M.; Kirkland, A.; Bisht, P.; El-Brolosy, M. A.; Jaenisch, R.; Bell, G. W.; Weissman, J. S.; Griffith, E. C.; Hrvatin, S.
10.1101/2024.07.25.605098 — cell biology — Posted on 2024-11-19
1830 Classification of Parkinson's Disease and Delineating Progression Markers from the Sebum Volatilome
Walton-Doyle, C.; Heim, B.; Sinclair, E.; Lim, S. H.; Hollywood, K.; Milne, J.; Holzknecht, E.; Stefani, A.; Hogl, B.; Seppi, K.; Silverdale, M.; Poewe, W.; Barran, P.; Trivedi, D. K.
10.1101/2023.03.01.530578 — neuroscience — Posted on 2024-11-19
1837 Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function
Barisa, M.; Zappa, E.; Muller, H.; Shah, R.; Buhl, J.; Draper, B.; Himsworth, C.; Bowers, C.; Munnings-Tomes, S.; Nicolaidou, M.; Morlando, S.; Birley, K.; Leboreiro-Babe, C.; Vitali, A.; Privitera, L.; O'Sullivan, K.; Greppi, A.; Buschhaus, M.; Barrera Roman, M.; de Blank, S.; van den Ham, F.; van 't Veld, B. R.; Ferry, G.; Donovan, L. K.; Chesler, L.; Molenaar, J. J.; Drost, J.; Rios, A. C.; Chester, K.; Wienke, J.; Anderson, J.
10.1101/2024.02.19.580939 — bioengineering — Posted on 2024-11-19
1839 Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis
Pourdanandeh, M.; Sechet, V.; Carpentier, L.; Reveillon, D.; Herve, F.; Hubert, C.; Hess, P.; Selander, E.
10.1101/2024.07.17.603891 — ecology — Posted on 2024-11-19
1840 SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification
Padovani, F.; Cavka, I.; Neves, A. R. R.; Lopez, C. P.; Al-Refaie, N.; Bolcato, L.; Chatzitheodoridou, D.; Chadha, Y.; Su, X. A.; Lengefeld, J.; Cabianca, D. S.; Köhler, S.; Schmoller, K. M.
10.1101/2024.10.22.619610 — cell biology — Posted on 2024-11-19
1845 Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk using QCM-D
Kerivan, E. M.; Amari, V. N.; Weeks, W. B.; Hardin, L. H.; Tobin, L.; Alazzam, O. Y.; Reinemann, D.
10.1101/2024.02.26.582155 — biophysics — Posted on 2024-11-19
1848 The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ
Martin, P. R.; Nieminuszczy, J.; Kozik, Z.; Jakub, N.; Lecot, M.; Vorhauser, J.; Lane, K. A.; Kanellou, A.; Mansfeld, J.; Pearl, L. H.; Oliver, A.; Downs, J. A.; Chaudhary, J.; Day, M.; Niedzwiedz, W.
10.1101/2024.11.12.621593 — molecular biology — Posted on 2024-11-19
1849 On the Role of VP3-PI3P Interaction in Birnavirus Endosomal Membrane Targeting
Zanetti, F. A.; Fernandez, I.; Baquero, E.; Guardado-Calvo, P.; Ferrino-Iriarte, A.; Dubois, S.; Morel, E.; Alfonso, V.; Aguilera, M. O.; Celayes, E. E.; Polo, L. M.; Suhaiman, L.; Galassi, V. V.; Chiarpotti, M. V.; Allende, C.; Rodriguez, J. M.; Caston, J. R.; Lijavetzky, D.; Taboga, O.; Colombo, M. I.; Del Popolo, M. G.; Rey, F. A.; Delgui, L. R.
10.1101/2024.02.20.581221 — microbiology — Posted on 2024-11-19
1855 A global effort to benchmark predictive models and reveal mechanistic diversity in long-term stroke outcomes
Matsulevits, A.; Alvez, P.; Atzori, M.; Beyh, A.; Corbetta, M.; Del Pup, F.; Dulyan, L.; Foulon, C.; Hope, T.; Ioannucci, S.; Jobard, G.; Lemaitre, H.; Neville, D.; Nozais, V.; Rorden, C.; Saprikis, O.-V.; Sibon, I.; Sperber, C.; Teghipco, A.; Thirion, B.; Tshimanga, L. F.; Umarova, R.; Vaidelyte, E. B.; van den Hoven, E.; Villar Rodriguez, E.; Zanola, A.; Tourdias, T.; Thiebaut de Schotten, M.
10.1101/2024.10.17.618691 — neuroscience — Posted on 2024-11-19
1856 Molecular Polymorphism of tau aggregates in Pick's disease
Liu, J.; Stewart, T. C.; Hyman, B. T.; Burghammer, M.; Cotte, M.; Makowski, L.
10.1101/2024.11.19.624253 — neuroscience — Posted on 2024-11-19
1860 Odorant representations indicate nonlinear processing across the olfactory system
Olivares, J.; Orio, P.; Sadilek, V.; Schmachtenberg, O.; Canales-Johnson, A.
10.1101/2022.04.15.488302 — neuroscience — Posted on 2024-11-19
1872 A Comprehensive Bibliometric Investigation on Antimicrobials from Fungal Origins with a Biotechnological Perspective
Da Silva, L. L.; Silva, K.; Correa, T.; Campos da Paz, M.; Martin, G.; Goncalves, A. A. M.; Belo, V. S.; Gontijo, T. S.; Galdino, A.
10.1101/2024.11.18.624177 — microbiology — Posted on 2024-11-19
1873 Evaluation of Brain Age as a Specific Marker of Brain Health
Tan, T. W. K.; Nguyen, K.-N.; Zhang, C.; Kong, R.; Cheng, S. F.; Ji, F.; Chong, J. S. X.; Chong, E. J. Y.; Venketasubramanian, N.; Orban, C.; Chee, M. W. L.; Chen, C.; Zhou, J. H.; Yeo, B. T. T.; Alzheimer's Disease Neuroimaging Initiative, ; Australian Imaging Biomarkers and Lifestyle Study of Aging,
10.1101/2024.11.16.623903 — neuroscience — Posted on 2024-11-19
1875 Entomological investigations into yellow fever outbreak in northern Ghana
Osei, J. H. N.; Pi-Bansa, S.; Frempong, K. K.; Ofei, M.; Boakye, H. A.; Ansah-Owusu, J.; Akorful, S.-C. A.; Malm, R. O.-T.; Tawiah-Mensah, C. N. L.; Abudu, M.; Asafu-Adjaye, A.; Addo, S. O.; Agbodzi, B.; Bentil, R.; Pratt, D.; Nimo-Paintsil, S.; Bonney, J. H. K.; Appawu, M. A.; Koffi, M.-C. A. A.; Coleman, S.; Captain-Esoah, M.; Kubio, C.; Boakye, D. A.; Dadzie, S. K.
10.1101/2024.11.18.624057 — zoology — Posted on 2024-11-19
1877 Decreased SNCA Expression in Whole-Blood RNA Analysis of Parkinson's Disease Adjusting for Lymphocytes
Xu, K.; Violich, I.; Hutchins, E.; Alsop, E.; Nalls, M. A.; Blauwendraat, C.; Gibbs, J. R.; Cookson, M. R.; Moore, A.; Van Keuren-Jensen, K.; Craig, D. W.
10.1101/2024.11.18.623684 — bioinformatics — Posted on 2024-11-19
1878 Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms
Bell, C.; Kilo, L.; Gottschalk, D.; Kern, H.; Arian, J.; Deneke, L.; Kobler, O.; Rickert, C.; Strauss, J.; Heine, M.; Duch, C.; Ryglewski, S.
10.1101/2024.06.14.598978 — neuroscience — Posted on 2024-11-19
1880 Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
Huang, Y.; Fan, Y.; Liu, Y.; Liu, X.; Li, W.; Yang, Y.; Zhang, Z.; Ma, S.; shuhui, j.; Chen, S.; Shu, H.; Feng, W.; Wang, K.; He, Q.; Qi, W.; Fan, Y.; Li, X.; Liu, M.
10.1101/2024.09.17.613598 — physiology — Posted on 2024-11-19
1888 Disordered glass nanowire substrates produce in vivo-like astrocyte morphology revealed by optical diffraction tomography
Anantha, P.; Kim, J. H.; Saracino, E.; Raj, P.; Lucarini, I.; Tanwar, S.; Chen, J.; Gu, L.; Agrawal, J.; Convertino, A.; Barman, I.
10.1101/2024.11.14.623676 — cell biology — Posted on 2024-11-19
1889 NAD+ activates renal metabolism and protects from chronic kidney disease in a model of Alport syndrome
Jones, B. A.; Gisch, D. L.; Myakala, K.; Sadiq, A.; Cheng, Y.-H.; Taranenko, E.; Panov, J.; Korolowicz, K.; Melo Ferreira, R.; Yang, X.; Santo, B. A.; Allen, K. C.; Wang, X.; Yoshida, T.; Rosenberg, A. Z.; Jain, S.; Eadon, M. T.; Levi, M.
10.1101/2024.02.26.580911 — molecular biology — Posted on 2024-11-19
1890 Conserved transcription factors coordinate synaptic gene expression through repression
Kentro, J. A.; Singh, G.; Pham, T. M.; Currie, J.; Khullar, S.; Medeiros, A. T.; Larschan, E.; O'Connor-Giles, K. M.
10.1101/2024.10.30.621128 — neuroscience — Posted on 2024-11-19
1893 Evaluating discordant somatic calls across mutation discovery approaches to minimize false negative drug-resistant findings
Lin, H.-F.; Chien, P.-M.; Cheng, C.; Yuan, T.-H.; Wang, Y.-B.; Chen, P.-L.; Chen, C.-Y.; Huang, J.-H.; Hsu, J. S.
10.1101/2023.10.26.562640 — bioinformatics — Posted on 2024-11-19
1894 Predicting purification process fit of monoclonal antibodies using machine learning
Maier, A. J.; Cha, M.; Burgess, S.; Wang, A.; Cuellar, C.; Kim, S.; Rajan, N. S.; Neyyan, J.; Sengupta, R.; O'Connor, K.; Ott, N.; Williams, A. J.
10.1101/2024.08.05.606711 — bioinformatics — Posted on 2024-11-19
1896 Improved protein binder design using -pairing targeted RFdiffusion
Sappington, I.; Toul, M.; Lee, D. S.; Robinson, S. A.; Goreshnik, I.; McCurdy, C.; Chan, T. C.; Buchholz, N.; Huang, B.; Vafeados, D.; Roullier, N.; Garcia-Sanchez, M.; Glögl, M.; Kim, C.; Watson, J. L.; Torres, S. V.; Verschueren, K. H. G.; Verstraete, K.; Hinck, C. S.; Bernard-Valle, M.; Coventry, B.; Sims, J. N.; Ahn, G.; Wang, X.; Hinck, A. P.; Jenkins, T. P.; Ruohola-Baker, H.; Banik, S.; Savvides, S. N.; Baker, D.
10.1101/2024.10.11.617496 — biochemistry — Posted on 2024-11-19
1898 NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts)
de Visser, M. C.; France, J.; McCartney-Melstad, E.; Bucciarelli, G. M.; Theodoropoulos, A.; Shaffer, H. B.; Wielstra, B.
10.1101/2024.10.25.620290 — genomics — Posted on 2024-11-19
1899 In vivo human uterine temperature, pH, and uterine fluid composition analysis
Tarahomi, M.; Zagers, M. S.; Zafardoust, S.; Mohammadzadeh, A.; Fathi, Z.; Sareban, H.; Fatemi, F.; Fakhr, S.; Hamer, G.; Repping, S.; Schrauwen, F.; van Straalen, J. P.; Vaz, F. M.; van Wely, M.; Mastenbroek, S.
10.1101/2024.11.18.623470 — developmental biology — Posted on 2024-11-19
1901 RNAi epimutations conferring antifungal drug resistance are inheritable
Perez-Arques, C.; Navarro-Mendoza, M. I.; Xu, Z.; Walther, G.; Heitman, J.
10.1101/2024.10.15.618540 — microbiology — Posted on 2024-11-19
1902 An animal model for autoinflammation with infantile enterocolitis
Wang, Y.; Gao, J. Z.; Gurung, P.; Short, S. P.; Xiong, Y.; Kang, Z.
10.1101/2024.11.16.623944 — immunology — Posted on 2024-11-19
1903 Microglia States are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's Disease
Li, B.; Wang, S.; Kerman, B.; Hugo, C.; Shwab, E. K.; Shu, C.; Chiba-Falek, O.; Arvanitakis, Z.; Yassine, H. N.
10.1101/2024.11.18.624141 — neuroscience — Posted on 2024-11-19
1904 String-pulling by the common marmoset
Bertrand, M.; Karkuszewski, M.; Kersten, R.; Orban de Xivry, J.-J.; Pruszynski, J. A.
10.1101/2024.10.25.620352 — neuroscience — Posted on 2024-11-19
1908 ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images
Wu, E.; Bieniosek, M.; Wu, Z.; Thakkar, N.; Charville, G. W.; Makky, A.; Schürch, C.; Huyghe, J. R.; Peters, U.; Li, C. I.; Li, L.; Giba, H.; Behera, V.; Raman, A.; Trevino, A. E.; Mayer, A. T.; Zou, J.
10.1101/2024.11.10.622859 — pathology — Posted on 2024-11-19
1909 PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data
de Visser, M. C.; Ploeg, C. v. d.; Cvijanovic, M.; Vucic, T.; Theodoropoulos, A.; Wielstra, B.
10.1101/2024.10.25.620064 — bioengineering — Posted on 2024-11-19
1911 Multiscale Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bioimaging
Bai, Y.; Jones, M.; Ojeda, L. S.; Cuala, J.; Cherchia, L.; Georgia, S. K.; Fraser, S. E.; Truong, T. V.
10.1101/2024.09.30.615205 — bioengineering — Posted on 2024-11-19
1916 A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
Bacot, T.; Haberkorn, C.; Guilliet, J.; Cattel, J.; Kefi, M.; Nadalin, L.; Filee, J.; Boyer, F.; Gaude, T.; Laporte, F.; Tutagata, J.; Vontas, J.; Dusfour, I.; Bonneville, J.-M.; David, J.-P.
10.1101/2024.04.03.587871 — evolutionary biology — Posted on 2024-11-19
1918 Evaluating the Roles of Drift and Selection in Trait Loss along an Elevational Gradient
Buysse, S. F.; Perez, S. G.; Puzey, J. R.; Garrison, A.; Bradburd, G. S.; Oakley, C. G.; Pico, X.; Tonsor, S. J.; Josephs, E. B.; Conner, J. K.
10.1101/2024.06.12.598645 — evolutionary biology — Posted on 2024-11-19
1921 Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish
Baltaci, O. F.; Usseglio Gaudi, A.; Dudczig, S.; Wang, W.; Rondon-Galeano, M. C.; Lim, Y.-W.; Rae, J.; Lagendijk, A.; Parton, R. G.; Farley, A.; Hogan, B. M.
10.1101/2024.11.18.624089 — developmental biology — Posted on 2024-11-19
1922 Inhibition of GEF-H1-RhoA signaling in inflammation with a stapled peptide mimicry of the RhoA67-78 helix
Gathmann, C.; Liu, T.; Yang, S.; Wang, W. C.; Chan, A. W. E.; Matter, K.; Balda, M.; Selwood, D. L.
10.1101/2024.11.18.624118 — cell biology — Posted on 2024-11-19
1924 Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis
Zhao, Z.; Hu, L.; Song, B.; Jiang, T.; Wu, Q.; Lin, J.; Li, X.; Cai, Y.; Li, J.; Qian, B.; Liu, S.; Lang, J.; Yang, Z.
10.1101/2024.06.08.598066 — cell biology — Posted on 2024-11-19
1925 Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping
de Visser, M. C.; Meilink, W. R. M.; Theodoropoulos, A.; Fahrbach, M.; Wielstra, B.
10.1101/2024.10.25.620256 — molecular biology — Posted on 2024-11-19
1926 Aeromonas hydrophila CobQ is a new type of NAD+- and Zn2+-independent protein lysine deacetylase
Wang, Y.; Wang, G.; Zhang, L.; Cai, Q.; Lin, M.; Huang, D.; Xie, Y.; Lin, W.; Lin, X.
10.1101/2024.03.22.586220 — microbiology — Posted on 2024-11-19
1928 Decoding the chemical language of RiPPs from the untapped Archaea domain
Song, Z.-m.; Cai, C.; Gao, Y.; Lin, X.; Yang, Q.; Zhang, D.; Wu, G.; Liang, H.; Zhuo, Q.; Zhang, J.; Cai, P.; Jiang, H.; Liu, W.; Li, Y.-x.
10.1101/2024.10.07.616454 — microbiology — Posted on 2024-11-19
1931 Harmonization of Diffusion MRI-based Structural Connectomes for Multi-site Studies
Shen, R. S.; Parker, D.; Chen, A. A.; Yerys, B. E.; Tunc, B.; Shinohara, R. T.; Verma, R.
10.1101/2024.10.08.617340 — neuroscience — Posted on 2024-11-19
1933 Disrupted activation of pain networks during attack imagery in patients with episodic migraine
Perdigao, A.; Esteves, I.; Fouto, A.; Ruiz-Tagle, A.; Caetano, G.; Gil-Gouveia, R.; Figueiredo, P.
10.1101/2024.11.18.624121 — neuroscience — Posted on 2024-11-19
1934 Multimodal laminar characterization of visual areas along the cortical hierarchy
Pizzuti, A.; Bazin, P.-L.; Ivanov, D.; Dresbach, S.; Peters, J.; Goebel, R. W.; Gulban, O. F.
10.1101/2024.11.18.624072 — neuroscience — Posted on 2024-11-19
1937 Delta phase-dependent modulation of temporal predictions by parietal transcranial alternating current stimulation
Burke, R.; Maye, A.; Misselhorn, J.; Fiene, M.; Engelhardt, F. J.; Schneider, T. R.; Engel, A. K.
10.1101/2024.11.18.624126 — neuroscience — Posted on 2024-11-19
1938 Decoding Visual Spatial Attention Control
Meyyappan, S.; Rajan, A.; Yang, Q.; Mangun, G. R.; Ding, M.
10.1101/2023.08.05.552084 — neuroscience — Posted on 2024-11-19
1940 Therapeutic window for treatment of prion disease defined by timed depletion of Prion protein
Bradford, B. M.; Marshall, A.; Tuzi, N. L.; Kisielewski, D.; Summers, K. M.; Perry, V. H.; Piccardo, P.; Clarke, A. R.; Manson, J. C.
10.1101/2024.11.18.624122 — neuroscience — Posted on 2024-11-19
1941 Mapping the impact of DUSP6 in an ADHD iPSC derived-dopaminergic neuronal model
Namipashaki, A.; Hellyer, S. D.; Arnatkeviciute, A.; Walsh, K.; Nowell, C. J.; Polo, J. M.; Gregory, K. J.; Bellgrove, M. A.; Hawi, Z.
10.1101/2024.11.18.624053 — neuroscience — Posted on 2024-11-19
1942 Behavioral risk models explain locomotor and balance changes when walking at virtual heights
Seddighi, N.; Woo, N. J.; Montoya, J.; Kreter, N.; Clark, M.; Williams, A. M.; Raffegeau, T. E.; Fino, P. C.
10.1101/2024.11.18.624196 — neuroscience — Posted on 2024-11-19
1944 Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
Lane, A. R.; Scher, N. E.; Bhattacharjee, S.; Zlatic, S. A.; Roberts, A. M.; Gokhale, A.; Singleton, K. S.; Duong, D. M.; McKenna, M.; Liu, W. L.; Baiju, A.; Moctezuma, F. G. R.; Tran, T.; Patel, A.; Clayton, L. B.; Petris, M. J.; Wood, L. B.; Patgiri, A.; Vrailas-Mortimer, A. D.; Cox, D. N.; Roberts, B. R.; Werner, E.; Faundez, V.
10.1101/2024.09.09.612106 — neuroscience — Posted on 2024-11-19
1945 Challenges and promises in optimising a non-clinical protocol of intracerebroventricular human neural stem cell transplantation in ALS
Lombardi, I.; Ferrero, C.; Vulcano, E.; Rasa', D. M.; Gelati, M.; Campos, D. P.; Carletti, R. M.; De La Morena, S.; Profico, D. C.; Longobardi, S.; Lazzarino, E.; Perciballi, E.; Rosati, J.; Perez, S. M.; Vercelli, A.; Boido, M. M.; Ferrari, D.
10.1101/2024.11.18.624143 — neuroscience — Posted on 2024-11-19
1946 An adaptable, reusable, and light implant for chronic Neuropixels probes
Bimbard, C.; Takacs, F.; Catarino, J. A.; Fabre, J. M.; Gupta, S.; Lenzi, S. C.; Melin, M. D.; O'Neill, N.; Orsolic, I.; Robacha, M.; Street, J. S.; Teixeira, J.; Townsend, S.; van Beest, E. H.; Zhang, A. M.; Churchland, A. K.; Duan, C. A.; Harris, K. D.; Kullmann, D. M.; Lignani, G.; Mainen, Z. F.; Margrie, T. W.; Rochefort, N. L.; Wikenheiser, A. M.; Carandini, M.; Coen, P.
10.1101/2023.08.03.551752 — neuroscience — Posted on 2024-11-19
1951 Inter- and Intrahemispheric Sources of Vestibular Signals to V1
Bouvier, G.; Sanzeni, A.; Hamada, E.; Brunel, N.; Scanziani, M.
10.1101/2024.11.18.624137 — neuroscience — Posted on 2024-11-19
1954 Profiling Human iPSC-Derived Sensory Neurons for Analgesic Drug Screening Using a Multi-Electrode Array
Kuete, C. F.; Vazquez, R. G.; Truong, V.; Walsh, P.; Price, T.; Biswas, S.; Dussor, G.; Pancrazio, J.; Kolber, B.
10.1101/2024.11.18.623405 — neuroscience — Posted on 2024-11-19
1955 Dynamic Changes in Chloride Homeostasis Coordinate Midbrain Inhibitory Network Activity during Reward Learning
Woo, J.; Uprety, A.; Reid, D.; Chang, I.; Samuel, A. K.; Schuch, H. d. C.; Swain, C. C.; Ostroumov, A.
10.1101/2024.11.18.624156 — neuroscience — Posted on 2024-11-19
1959 Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts
Du, H.; Rose, J. P.; Bons, J.; Guo, L.; Valentino, T. R.; Wu, F.; Burton, J. B.; Basisty, N.; Manwaring-Mueller, M.; Makhijani, P.; Chen, N.; Chang, V.; Winer, S.; Campisi, J.; Furman, D.; Nagy, A.; Schilling, B.; Winer, D.
10.1101/2024.11.18.623471 — cell biology — Posted on 2024-11-19
1961 Age-related myelin deficits in the auditory brain stem contribute to cocktail party-deficits
Poleg, S.; Li, B.-Z.; Sergison, M.; Ridenour, M.; Hughes, E. G.; Tollin, D.; Klug, A.
10.1101/2024.07.29.605710 — neuroscience — Posted on 2024-11-19
1962 Neuronal heterogeneity in the medial septum and diagonal band of Broca: classes and continua
Kuhn, F.; Mocellin, P.; Pupe, S.; Wang, L.; Lemire, A. L.; Sosulina, L.; Barnstedt, O.; Spruston, N.; Cembrowski, M. S.; Remy, S.
10.1101/2024.08.27.609593 — neuroscience — Posted on 2024-11-19
1963 Results of the Protein Engineering Tournament: An Open Science Benchmark for Protein Modeling and Design
Armer, C.; Kane, H.; Cortade, D. L.; Redestig, H.; Estell, D. A.; Yusuf, A.; Rollins, N. J.; Spinner, H.; Marks, D.; Brunette, T.; Kelly, P. J.; DeBenedictis, E.
10.1101/2024.08.12.606135 — bioengineering — Posted on 2024-11-19
1964 Effective conservation decisions require models designed for purpose: a case study for boreal caribou in Ontario's Ring of Fire
Dyson, M. E.; Endicott, S.; Simpkins, C.; Turner, J. W.; Avery-Gomm, S.; Johnson, C. A.; Leblond, M.; Neilson, E.; Rempel, R. S.; Wiebe, P.; Baltzer, J. L.; Hughes, J.; Stewart, F. E. C.
10.1101/2022.06.01.494350 — ecology — Posted on 2024-11-19
1965 Biofilm lifestyle as a common trait of ammonia-oxidizing archaea
Dreer, M.; Pribasnig, T.; Hodgskiss, L. H.; Luo, Z.-H.; Pozaric, F.; Schleper, C.
10.1101/2024.11.18.624116 — microbiology — Posted on 2024-11-18
1966 Identification of TAP2 protein variants resistant to inhibition by the HSV1 ICP47 protein
Nagy, G.; Presley, R.; Dhar, S.; Jeon, H.; Moreira, L.; Tull, O.; Gupta, A.; Chung, D.; Tsichlis, P. N.; Parvin, J. D.
10.1101/2024.11.18.624061 — immunology — Posted on 2024-11-18
1968 Back to the horns: a reconstruction of the ancestral horn state through distinct types of recombination events.
Upadhyay, M.; Graf, A.; pogorevc, N.; Seichter, D.; Russ, I.; Krebs, S.; Meier, S.; Medugorac, I.
10.1101/2024.11.18.624115 — genomics — Posted on 2024-11-18
1969 Host-specific adaptation of Legionella pneumophila to single and multiple hosts
Moreno, A. B.; Paranjape, K.; Cederblom, M.; Kay, E.; Dobre-Lereanu, C.; Andersson, D. I.; Guy, L.
10.1101/2024.11.18.624128 — evolutionary biology — Posted on 2024-11-18
1970 Sphae: An automated toolkit for predicting phage therapy candidates from sequencing data
Papudeshi, B.; Roach, M. J.; Mallawaarachchi, V.; Bouras, G.; Grigson, S. R.; Giles, S. K.; Harker, C. M.; Hutton, A. L. K.; Tarasenko, A.; Inglis, L. K.; Vega, A. A.; Souza, C.; Boling, L.; Hajama, H.; Cobian-Guemes, A. G.; Segall, A.; Dinsdale, E. A.; Edwards, R. A.
10.1101/2024.11.18.624194 — bioinformatics — Posted on 2024-11-18
1971 High-Throughput Screening Reveals Potential Inhibitors Targeting Trimethoprim-Resistant DfrA1 Protein in Klebsiella pneumoniae and Escherichia coli
Hasnat, S.; Rahman, S.; Alam, M. B.; Suin, F. M.; Yeasmin, F.; Suha, T.; Supty, N. T.; Sabila, S.; Chowdhury, A.; Shahinuzzaman, A. D. A.; Mahbub, M. M.; Hoque, M. N.; Islam, T.
10.1101/2024.11.18.624070 — bioinformatics — Posted on 2024-11-18
1973 Accurate de novo design of high-affinity protein binding macrocycles using deep learning
Rettie, S.; Juergens, D.; Adebomi, V.; Bueso, Y. F.; Zhao, Q.; Leveille, A.; Liu, A.; Bera, A.; Wilms, J.; Üffing, A.; Kang, A.; Brackenbrough, E.; Lamb, M.; Gerben, S.; Murray, A.; Levine, P.; Schneider, M.; Vasireddy, V.; Ovchinnikov, S.; Weiergräber, O.; Willbold, D.; Kritzer, J.; Mougous, J.; Baker, D.; DiMaio, F.; Bhardwaj, G.
10.1101/2024.11.18.622547 — biochemistry — Posted on 2024-11-18
1975 Analysis of ribosomes from the Wild-type and FMR1 knockout human embryonic stem cells
Kharbanda, T.; D'Souza, M. N.; Palakodeti, D.; Muddashetty, R. S.; Kutti, V. R.
10.1101/2024.11.18.624098 — biochemistry — Posted on 2024-11-18
1976 High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing
Ntekas, I.; Takayasu, L.; McKellar, D. W.; Grodner, B. M.; Holdener, C.; Schweitzer, P. A.; Sauthoff, M.; Shi, Q.; Brito, I. L.; De Vlaminck, I.
10.1101/2024.11.18.624127 — genomics — Posted on 2024-11-18
1978 Nitrogenase structural evolution across Earth s history
Cuevas, B.; Detemple, F.; Amritkar, K.; Garcia, A. K.; Seefeldt, L.; Einsle, O.; Kacar, B.
10.1101/2024.11.18.623660 — evolutionary biology — Posted on 2024-11-18
1980 Nanopore sequencing of intact aminoacylated tRNAs
White, L. K.; Radakovic, A.; Sajek, M. P.; Dobson, K.; Riemondy, K. A.; del Pozo, S.; Szostak, J. W.; Hesselberth, J. R.
10.1101/2024.11.18.623114 — molecular biology — Posted on 2024-11-18
1981 Lrif1 modulates Trim28-mediated repression of the Dux locus in mouse embryonic stem cells
Sikrova, D.; Gonzalez-Prieto;, R.; Vertegaal, A. C. O.; Balog, J.; Daxinger, L.; van der Maarel, S. M.
10.1101/2024.11.18.624083 — molecular biology — Posted on 2024-11-18
1982 The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region and impaired by neurodevelopmental disease-related truncations
Dell'Oca, M.; Bozzo, S. B.; Vaglietti, S.; Gurgone, A.; Cardinale, V.; Ragazzini, G.; Alessandrini, A.; Colnaghi, L.; Ghirardi, M.; Giustetto, M.; Fiumara, F.
10.1101/2024.11.18.624084 — molecular biology — Posted on 2024-11-18
1983 Generating snoRNA-guided Programmable 2'O-methylation
Zhao, J.; Cockman, E.; Yin, X.; Chao, Y.; Pecot, C. V.; Holley, C. L.
10.1101/2024.11.18.622494 — molecular biology — Posted on 2024-11-18
1985 Combining metabolic engineering and fermentation optimization to achieve cost-effective oil production by Cutaneotrichosporon oleaginosus
Duman-Ozdamar, Z. E.; Veloo, R. M.; Tsepani, E.; Julsing, M. K.; Martins dos Santos, V. A. P.; Hugenholtz, J.; Suarez-Diez, M.
10.1101/2024.11.18.624102 — molecular biology — Posted on 2024-11-18
1986 Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC
Wang, Q.; Guo, Y.; Mellis, I. A.; Wu, M.; Mohri, H.; Gherasim, C.; Valdez, R.; Purpura, L. J.; Yin, M. T.; Gordon, A.; Ho, D. D.
10.1101/2024.11.17.624037 — microbiology — Posted on 2024-11-18
1987 Combining live cell fluorescence imaging with in situ cryo electron tomography sheds light on the septation process in Deinococcus radiodurans
Gaifas, L.; Kleman, J.-P.; Lacroix, F.; Schexnaydre, E.; Trouve, J.; Morlot, C.; Sandblad, L.; Gutsche, I.; TIMMINS, J.
10.1101/2024.11.18.624142 — microbiology — Posted on 2024-11-18
1988 sRNA-mediated crosstalk between cell wall stress and galactose metabolism in Staphylococcus aureus
Germain, M.; Robin, H.; Burel, A.; Massier, S.; Nalpas, N.; Hardouin, J.; Bouloc, P.; Rouillon, A.; Chabelskaya, S.
10.1101/2024.11.18.624069 — microbiology — Posted on 2024-11-18
1989 A quantitative approach to poxvirus infection reveals general correlates of antigen presentation and immunogenicity for viral CD8+ T cell epitopes
Witney, M. J.; Croft, N. P.; Wong, Y. C.; Smith, S. A.; Flesch, I. E.; Keller, E.; La Gruta, N. L.; Purcell, A. W.; Tscharke, D. C.
10.1101/2024.11.18.624047 — immunology — Posted on 2024-11-18
1990 A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits similar humoral immunity to that of postfusion gB in mice
Karthigeyan, K. P.; Connors, M.; Binuya, C. R.; Gross, M.; Fuller, A. S.; Crooks, C. M.; Wang, H.-Y.; Sponholtz, M. R.; Byrne, P. O.; Herbek, S.; Andy, C.; Gerber, L. M.; Campbell, J. D.; Williams, C. A.; Miller, I.; Yu, D.; Bottomley, M. J.; McLellan, J. S.; Permar, S. R.
10.1101/2024.11.18.624140 — immunology — Posted on 2024-11-18
1992 CD73 restrains mutant β-catenin oncogenic activity in endometrial carcinomas
Hirsch, R. M.; Premsankar, S.; Kurnit, K. C.; Chiou, L. F.; Rabjohns, E. M.; Lee, H. N.; Broaddus, R. R.; Vaziri, C.; Bowser, J. L.
10.1101/2024.11.18.624183 — cancer biology — Posted on 2024-11-18
1993 GOBoost: Leveraging Long-Tail Gene Ontology Terms for Accurate Protein Function Prediction
Zhang, L.; Wang, Y.; Chen, X.; Hou, J.; Si, D.; Ding, R.; Jiang, B.; Ledenko, H.; Cao, R.
10.1101/2024.11.16.623961 — bioinformatics — Posted on 2024-11-18
1996 Enhanced antifungal activity of NK-92 cells against Candida albicans mediated by a mannan-specific chimeric antigen receptor
Yamazaki de Campos, G.; Garcia Guimaraes, J.; Procopio Machado, M.; Oliveira-Brito, P. K. M.; Shin, B.; di Maio, A.; dos-Santos, D.; Vianna Bonini Palma, P.; dos Reis, T. F.; Goldman, G.; Palma, A. S.; Matthews, S.; Feizi, T.; Liu, Y.; da Silva, T. A.
10.1101/2024.11.18.623666 — bioengineering — Posted on 2024-11-18
2003 Isolated Mouse Adult Cardiomyocytes Display Minimal Mitochondrial ATP Demand and Maximal Reliance on Glycolysis
Mattam, U.; Talari, N. K.; Rao Sathyanarayana, A.; Mia, S.; Frazier, J.; Slone, S.; Drosatos, K.; Chella Krishnan, K.
10.1101/2024.11.17.623751 — cell biology — Posted on 2024-11-18
2004 Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets
Liu, S.; Wipf, I.; Joglekar, A.; Freshly, A.; Bovee, C.; Kim, L.; Richtsmeier, S.; Peachee, S.; Kopriva, S.; Vikram, A.; El Ladiki, D.; Ilerisoy, F.; Ilerisoy, B.; Sagona, G.; Jun, C.; Giedt, M. S.; Tootle, T. L.; Ankrum, J. A.; Imai, Y.
10.1101/2024.11.17.624030 — molecular biology — Posted on 2024-11-18
2005 Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation.
Kulkarni, H. S.; Tague, L. K.; Calabrese, D. R.; Liao, F.; Liu, Z.; Garnica, L.; Shankar, N.; Wu, X.; Kulkarni, D. H.; Bernadt, C.; Byers, D. E.; Chen, C.; Huang, H. J.; Witt, C. A.; Hachem, R. R.; Kreisel, D.; Atkinson, J. P.; Greenland, J. R.; Gelman, A. E.
10.1101/2024.11.17.623951 — immunology — Posted on 2024-11-18
2006 Simultaneous loss of CAMK2A and CAMK2B reveals endogenous in vivo substrates
Rigter, P. M. F.; Bezstarosti, K.; Koc, O. C.; Perfitt, T. L.; Demmers, J. A.; Colbran, R. J.; Stratton, M. J.; Elgersma, Y.; van Woerden, G. M.
10.1101/2024.11.17.624016 — neuroscience — Posted on 2024-11-18
2009 High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissue
Haines, M.; Thorup, J. R.; Gohsman, S.; Ctortecka, C.; Newton, C.; Rohrer, D. C.; Hostetter, G.; Mani, D. R.; Gillette, M. A.; Satpathy, S.; Carr, S. A.
10.1101/2024.11.17.624038 — systems biology — Posted on 2024-11-18
2010 Multi-purpose controllable protein generation via prompted language models
Wang, Z.; Chen, B.; Ding, K.; Cao, J.; Qin, M.; Niu, Y.; Zhuang, X.; Li, X.; Feng, K.; Xu, T.; Zhang, N.; Yu, H.; Zhang, Q.; Chen, H.
10.1101/2024.11.17.624051 — synthetic biology — Posted on 2024-11-18
2011 Mitochondrial genome-encoded mitomiRs regulate cellular plasticity and susceptibility to ferroptosis in triple-negative breast cancer
Kandettu, A.; Ghosal, J.; Tharayil, J. S.; Kuthethur, R.; Mallya, S.; Narasimhamurthy, R. K.; Mumbrekar, K. D.; Subbannayya, Y.; Kumar, N. A. N.; Radhakrishnan, R.; Kabekkodu, S. P.; Chakrabarty, S.
10.1101/2024.11.16.623958 — cancer biology — Posted on 2024-11-18
2012 Engineered paediatric tumours retain patient tumour genotype and phenotype for precision medicine.
Jung, M.; Poltavets, V.; Skhinas, J.; Ghamrawi, S.; Tax, G.; Kamili, A.; Xie, J.; Graber, P.; Mao, J.; Wong, M.; Cui, L.; Kimpton, K.; Venkat, P.; Mayoh, C.; Fleuren, E.; Fordham, A.; Barger, Z.; Grady, J. P.; Thomas, D. M.; Du, E.; Cowley, M.; Gifford, A. J.; Fletcher, J.; Lau, L.; Dolman, M. E. M.; Gooding, J. J.; Kavallaris, M.
10.1101/2024.11.17.619539 — cancer biology — Posted on 2024-11-18
2017 Mechanism of cooperative strigolactone perception by the MAX2 ubiquitin ligase-receptor-substrate complex
Arold, S. T.; Vancea, A. I.; Huntington, B.; Steinchen, W.; Savva, C. G.; Shahul Hameed, U. F.
10.1101/2024.11.17.623987 — biophysics — Posted on 2024-11-18
2018 Blackbird: structural variant detection using synthetic and low-coverage long-reads
Meleshko, D.; Yang, R.; Maharajan, S.; Danko, D. C.; Korobeynikov, A.; Hajirasouliha, I.
10.1101/2024.11.17.624011 — bioinformatics — Posted on 2024-11-18
2024 Clair3-RNA: A deep learning-based small variant caller for long-read RNA sequencing data
Zheng, Z.; Yu, X.; Chen, L.; Lee, Y.-L.; Xin, C.; Wong, A. O. K.; Jain, M.; Kesharwani, R. K.; Sedlazeck, F. J.; Luo, R.
10.1101/2024.11.17.624050 — bioinformatics — Posted on 2024-11-18
2025 Squidiff: Predicting cellular development and responses to perturbations using a diffusion model
He, S.; Zhu, Y.; Tavakol, D. N.; Ye, H.; Lao, Y.-H.; Zhu, Z.; Xu, C.; Chauhan, S.; Garty, g.; Tomer, R.; Vunjak-Novakovic, G.; Zou, J.; Azizi, E.; Leong, K. W.
10.1101/2024.11.16.623974 — bioinformatics — Posted on 2024-11-18
2027 Design of highly potent anti-biofilm, antimicrobial peptides using explainable artificial intelligence
Pikalyova, K.; Akhmetshin, T.; Orlov, A.; Haney, E. F.; Akhoundsadegh, N.; You, J.; Hancock, R. E. W.; Horvath, D.; Marcou, G.; Cherkasov, A.; Varnek, A.
10.1101/2024.11.17.622654 — bioinformatics — Posted on 2024-11-18
2028 Time-Dependent Material Properties and Composition of the Nonhuman Primate Uterine Layers Through Gestation
Fodera, D. M.; Xu, E. Z.; Duarte-Cordon, C. A.; Wyss, M.; Fang, S.; Chen, X.; Oyen, M. L.; Rosado-Mendez, I.; Hall, T.; Vink, J.; Feltovich, H.; Myers, K. M.
10.1101/2024.11.17.624020 — bioengineering — Posted on 2024-11-18
2030 A nucleic acid prodrug activates mitochondrial respiration and extends lifespan
Anada, T.; Kawahara, M.; Shimada, T.; Kuroda, R.; Kage-Nakadai, E.; Kobayashi, S.; Tanaka, M.
10.1101/2024.11.16.623599 — bioengineering — Posted on 2024-11-18
2041 Unraveling Honey Bee's Waggle Dances in Natural Conditions with Video-Based Deep Learning
Grison, S.; Siddaganga, R.; Hedge, S.; Burridge, J.; Blok, P. M.; Krishnan, S.; Brockmann, A.; Guo, W.
10.1101/2024.11.16.623982 — ecology — Posted on 2024-11-18
2043 Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells
Kawasaki, T.; Nishimura, T.; Tani, N.; Ramos, C.; Karaulanov, E.; Shinya, M.; Saito, K.; Taylor, E.; Ketting, R. F.; Ishiguro, K.-i.; Tanaka, M.; Siegfried, K.; Sakai, N.
10.1101/2024.11.17.623901 — developmental biology — Posted on 2024-11-18
2046 Brain-wide representations of prior information in mouse decision-making
Findling, C.; Hubert, F.; International Brain Laboratory, ; Acerbi, L.; Benson, B.; Benson, J.; Birman, D.; Bonacchi, N.; Carandini, M.; Catarino, J. A.; Chapuis, G. A.; Churchland, A. K.; Dan, Y.; DeWitt, E. E.; Engel, T. A.; Fabbri, M.; Faulkner, M.; Fiete, I. R.; Freitas-Silva, L.; Gercek, B.; Harris, K. D.; Hausser, M.; Hofer, S. B.; Hu, F.; Huntenburg, J. M.; Khanal, A.; Krasniak, C.; Langdon, C.; Latham, P. E.; Lau, P. Y. P.; Mainen, Z.; Meijer, G. T.; Miska, N. J.; Mrsic-Flogel, T. D.; Noel, J.-P.; Nylund, K.; Pan-Vazquez, A.; Paninski, L.; Pillow, J.; Rossant, C.; Roth, N.; Schaeffer,
10.1101/2023.07.04.547684 — neuroscience — Posted on 2024-11-18
2049 Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes
Duong, T. V.-Q.; Yaw, A. M.; Zhou, G.; Sina, N.; Cherukuri, A. S.; Nguyen, D.; Cataldo, K.; Ly, N.; Sen, A.; Sempere, L.; Detrie, C.; Seiler, R.; Olomu, I.; Cortese, R. G.; Long, R.; Hoffmann, H. M.
10.1101/2024.11.16.622460 — physiology — Posted on 2024-11-18
2050 Integrative cardiovascular dose-response to graded lower body negative pressure
Whittle, R. S.; Keller, N.; Hall, E. A.; Patanam, S.; Dunbar, B. J.; Diaz-Artiles, A.
10.1101/2024.11.16.623934 — physiology — Posted on 2024-11-18
2052 A novel feeding mechanism: Sunbirds drink nectar via intralingual suction
Cuban, D.; Wang-Claypool, C.; Dalimunthe, Y.; Downs, C. T.; Bowie, R. C. K.; Brau, F.; Johnson, S.; Rico-Guevara, A.
10.1101/2024.05.14.594085 — biophysics — Posted on 2024-11-18
2054 Generative Approaches for Nucleotide Sequences to Enhance Non-coding RNA Classification
Chiquitto, A. G.; Oliveira, L. S.; Bugatti, P. H.; Saito, P. T. M.; Basham, M.; Raittz, R. T.; Paschoal, A. R.
10.1101/2024.11.17.623214 — bioinformatics — Posted on 2024-11-18
2056 Generative Models Validation via Manifold Recapitulation Analysis
Lazzaro, N.; Leonardi, G.; Marchesi, R.; Datres, M.; Saiani, A.; Tessadori, J.; Granados, A.; Henriksson, J.; Chierici, M.; Jurman, G.; Sales, G.; Tebaldi, T.
10.1101/2024.10.23.619602 — bioinformatics — Posted on 2024-11-18
2059 Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation
Sung, J. J.; Shaw, J. R.; Rezende, J. D.; Dharmaraj, S.; Cottingham, A. L.; Weldemariam, M. M.; Jones, J. W.; Kane, M. A.; Pearson, R. M.
10.1101/2024.11.13.623417 — bioengineering — Posted on 2024-11-18
2066 Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis
Herlo, R.; Schmidt, J. H.; Rombach, J.; Larsen, A. H.; Stoklund, M.; Perslev, M.; Nielsen, T. T. E.; Andersen, K. A.; Herenbrink, C.; Lycas, M. D.; Ejdrup, A.; Christensen, N.; Christensen, J. P.; Salman, M.; Herborg, F.; Gether, U.; Hauser, A.; Bassereau, P.; Perrais, D.; Madsen, k. L.
10.1101/2024.03.27.587027 — cell biology — Posted on 2024-11-18
2067 Haploinsufficiency of lysosomal enzyme genes in Alzheimers disease
Benitez, B. A.; Wallace, C. E.; Patel, M.; Nykanen, N.-P.; Yuede, C. M.; Eaton, S. L.; Pottier, C.; Cetin, A.; Johnson, M.; Bevan, M.; Gardiner, W. D.; Edwards, H. M.; Doherty, B. M.; Harrigan, R. T.; Kurian, D.; Wishart, T. M.; Smith, C.; Cirrito, J. R.; Sands, M.
10.1101/2024.11.16.623962 — neuroscience — Posted on 2024-11-18
2068 Representational learning by optimization of neural manifolds in an olfactory memory network
Hu, B.; Temiz, N. Z.; Chou, C.-N.; Rupprecht, P.; Meissner-Bernard, C.; Titze, B.; Chung, S.; Friedrich, R. W.
10.1101/2024.11.17.623906 — neuroscience — Posted on 2024-11-18
2071 Components of Mnemonic Metacognition Constitutionally Supported by High Gamma Activity Between the Precuneus and Hippocampus
Pan, K.; Guo, X.; Zheng, Z.; Zhu, Z.; Wu, H.; Zhu, J.; Ye, H.; Cai, Y.; Santos-Pata, D.; Zhang, J.; Kwok, S. C.; Jiang, H.
10.1101/2024.02.26.581526 — neuroscience — Posted on 2024-11-18
2073 PPD-H1 Improves Stress Resistance and Energy Metabolism to Boost Spike Fertility under High Ambient Temperatures
Lan, T.; Walla, A.; Colpan Karisan, K. E.; Buchmann, G.; Wewer, V.; Metzger, S.; Vardanega, I.; Haraldsson, E. B.; Helmsorig, G.; Thirulogachandar, V.; Simon, R.; von Korff, M.
10.1101/2024.11.04.621966 — plant biology — Posted on 2024-11-18
2075 Ephaptic coupling enables action potential conduction
Waaben, J.; Hofgaard, J. P.; Pick, G. L.; Loisel, C.; Engstrom, T.; Holstein-Rathlou, N.-H.; Poelzing, S.; Nielsen, M. S.
10.1101/2024.11.16.623938 — physiology — Posted on 2024-11-18
2077 Disease exacerbation by fibroblast inclusion in Duchenne Muscular Dystrophy MYOrganoids reveals limitations of microdystrophin therapeutic efficacy
Palmieri, L.; Pili, L.; Jaber, A.; Vu Hong, A.; Marcello, M.; El Khoury, R.; Brochiet, G.; Bigot, A.; Israeli, D.; Richard, I.; Albini, S.
10.1101/2023.07.26.550063 — bioengineering — Posted on 2024-11-18
2081 Intravenous gene therapy improves lifespan and clinical outcomes in feline Sandhoff Disease
Maguire, A. S.; Ta, L.; Gross, A. L.; Osterhoudt, D. E.; Cannon, J. S.; Hall, P. I.; Sandey, M.; Seyfried, T. N.; Gray-Edwards, H. L.; Sena-Esteves, M.; Martin, D. R.
10.1101/2024.11.15.623838 — pathology — Posted on 2024-11-18
2082 Contact-based thymidylate transfer promotes collective tumor growth
Siddiqui, M. A.; Roemer, A. M. A.; Pinna, L.; Ramesh, V.; Moeller, S. S.; Gollavilli, P. N.; Turtos, A. M.; Varghese, S.; Guldborg, L. B.; Palani, N. P.; Napoli, F.; Volante, M.; Bahena, L. J. C.; Velasco, M.; Somyajit, K.; Swietach, P.; Ceppi, P.
10.1101/2024.07.31.606056 — cancer biology — Posted on 2024-11-18
2083 Improved detection of differentially abundant proteins through FDR-control of peptide-identity-propagation
Solivais, A. J.; Boekweg, H.; Smith, L. M.; Shortreed, M. M.; Noble, W. S.; Payne, S. H.; Keich, U.
10.1101/2024.11.15.623880 — bioinformatics — Posted on 2024-11-18
2084 Mutagenic impact and evolutionary influence of radiotherapy in hematologic malignancies
Diamond, B.; Chahar, D.; Jain, M. D.; Poos, A. M.; Durante, M.; Ziccheddu, B.; Kaddoura, M.; Papadimitriou, M.; Maclachlan, K. H.; Jelinek, T.; Davies, F.; Figura, N. B.; Morgan, G.; Mai, E.; Weisel, K. C.; Fenk, R.; Raab, M. S.; Usmani, S.; Landgren, O.; Locke, F. L.; Goldschmidt, H.; Schatz, J. H.; Weinhold, N.; Maura, F.
10.1101/2024.11.15.623836 — genomics — Posted on 2024-11-18
2086 Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration
Shao, X.; Lin, X.; Zhou, H.; Wang, M.; Han, L.; Fu, X.; Li, S.; Zhu, S.; Zhou, S.; Yang, W.; Wang, J.; Hu, P.
10.1101/2024.04.29.591676 — cell biology — Posted on 2024-11-18
2087 Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation
Baron, K. R.; Oviedo, S.; Krasny, S.; Zaman, M.; Aldakhlallah, R.; Bora, P.; Mathur, P.; Pfeffer, G.; Bollong, M. J.; Shutt, T.; Grotjahn, D.; Wiseman, L.
10.1101/2024.06.10.598126 — cell biology — Posted on 2024-11-18
2088 Giving it a fair shake: A simple, fast, & efficient method to extract amatoxins from the death cap mushroom, Amanita phalloides
Adams, C. A.; Bever, C. S.; Blake-Hedges, J. M.; Brown, S.; Thompson, M. G.; Behie, S.; Keasling, J. D.; Shih, P.
10.1101/2024.11.15.623858 — microbiology — Posted on 2024-11-18
2090 Precision-cut lung slices in air-liquid interface (PCLS-ALI): A novel ex-vivo model for the study of Pulmonary Aspergillosis
Gonzales-Huerta, L. E.; Williams, T. J.; Aljohani, R.; Robertson, B. D.; Evans, C. A.; Armstrong-James, D.
10.1101/2024.11.15.615211 — immunology — Posted on 2024-11-18
2092 Sex-specific Regulation of Fentanyl Reward by the Circadian Transcription Factor NPAS2
Barko, K.; Shelton, M.; DePoy, L.; Gayden-Kozel, J.; Kim, S.-M.; Puig, S.; Xue, X.; Oliver-Smith, J.; Zhu, X.; Parekh, P.; Tseng, G.; Williams, B. R.; Freyberg, Z.; Logan, R. W.
10.1101/2024.11.12.623242 — neuroscience — Posted on 2024-11-18
2094 AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers
Weichert, F. G.; Inostroza, P. A.; Ahlheim, J.; Backhaus, T.; Brack, W.; Brauns, M.; Fink, P.; Krauss, M.; Svedberg, P.; Hollert, H.
10.1101/2024.11.15.623722 — pharmacology and toxicology — Posted on 2024-11-18
2095 Oncogene-induced senescence and senescence-associated secretory phenotype (SASP) determine the efficacy of palbociclib in PIK3CA mutated colorectal cancer
Cao, P.; Zhou, X.; Yang, S.; Shen, T.; Wang, S.; Yu, H.; Liu, X.; Gong, Y.; Wang, W.; Wang, H.; Zhou, T.; Wang, J.; Fan, Z.; Huang, M.; Qian, X.; Wang, X.; Wang, Q.; Yang, L.; Zhang, Y.; Lin, F.
10.1101/2024.11.15.623304 — cancer biology — Posted on 2024-11-18
2097 Age-Normalized Testosterone Peaks at Series B for Male Startup Founders
Moradian, J.; Dubrovsky, M.; Sama, M.; Korecky, P.; Goder, Y.; Vermeulen, D.
10.1101/2024.11.14.621994 — systems biology — Posted on 2024-11-18
2098 Self-organized acoustic behavior in bats arises from simple rules
Hase, K.; Miyazaki, T.; Oka, S.; Senoo, N.; Nishimori, H.; Shiraishi, M.; Yoda, K.; Kobayasi, K. I.; Hiryu, S.
10.1101/2024.11.18.623889 — animal behavior and cognition — Posted on 2024-11-18
2101 Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer
Camp, S. Y.; He, M. X.; Cuoco, M. S.; Saad, E.; Pimenta, E.; Meli, K.; Bakouny, Z.; Labaki, C.; Titchen, B. M.; Kang, Y. J.; Horst, J.; Trowbridge, R.; Shannon, E.; Helvie, K.; Thorner, A. R.; Vigneau, S.; Mayorga, A.; Kodali, J.; Lachmayr, H.; Bemus, M.; Park, J.; Choueiri, T.; Bi, K.; Van Allen, E. M.
10.1101/2024.11.15.623837 — cancer biology — Posted on 2024-11-18
2102 Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours
McDonald, P. C.; Topham, J. T.; Awrey, S.; Tavakoli, H.; Carroll, R.; Brown, W. S.; Gerbec, Z. J.; Kalloger, S. E.; Karasinska, J. M.; Tang, P.; Goodwin, R.; Jones, S. J. M.; Laskin, J.; Marra, M.; Morin, G. B.; Renouf, D. J.; Schaeffer, D. F.; Dedhar, S.
10.1101/2024.11.15.622336 — cancer biology — Posted on 2024-11-18
2105 MICROPLASTICS IN THE MOUNT TERMINILLO SNOW (RIETI, ITALY)
Pietrelli, L.; Menegoni, P.; Millesimi, I.; Sighicelli, M.; Baldi, M.; Schirone, B.
10.1101/2024.11.15.623744 — biochemistry — Posted on 2024-11-18
2109 High-resolution Cryo-EM visualises hydrated type I and IV pilus structures from enterotoxigenic Escherichia coli
Nakamura, S.; Kawahara, K.; Oki, H.; Iimori, M.; Muramoto, R.; Imai, T.; Gerle, C.; Shigematsu, H.; Matsuda, S.; Iida, T.
10.1101/2024.11.14.623551 — microbiology — Posted on 2024-11-18
2110 Versatile and Portable Cas12a-mediated Detection of Antibiotic Resistance Markers
Vargas-Reyes, M.; Alcantara, R.; Alfonsi, S.; Penaranda, K.; Petrelli, D.; Spurio, R.; Pajuelo, M.; Milon, P.
10.1101/2024.11.14.623642 — microbiology — Posted on 2024-11-18
2113 WITHDRAWN: Excitatory effects of dentate gyrus mossy cells on granule cells and area CA3: an vitro and in vivo study in adult mice.
Bernstein, H. L.; Lu, Y.-L.; Leary, P.; Jain, S.; LaFrancois, J. J.; Lacefield, C. O.; Botterill, J. J.; Scharfman, H. E.
10.1101/2020.06.06.137844 — neuroscience — Posted on 2024-11-18
2116 Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
Kremer, L. S.; Gao, G.; Rigoni, G.; Filograna, R.; Mennuni, M.; Wibom, R.; Vegvari, A.; Koolmeister, C.; Larsson, N.-G.
10.1101/2024.11.14.623694 — genetics — Posted on 2024-11-18
2118 Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onward
Dupas, M.-C.; Vincenti-Gonzalez, M. F.; Dhingra, M.; Guinat, C.; Vergne, T.; Wint, G. W.; Hendrickx, G.; Marsboom, C.; Gilbert, M.; Dellicour, S.
10.1101/2024.11.15.623755 — ecology — Posted on 2024-11-18
2121 3D-Printable Non-invasive Head Immobilization System for Non-Human Primates
Shahbazi, E.; Nguyen, D.; Lafer-Sousa, R.; Ryan, A.; Swedan, T.; Ma, T.; Dinh, A.; Azadi, R.; Afraz, A.
10.1101/2024.01.02.573832 — physiology — Posted on 2024-11-18
2123 Neuromorphic Imaging Cytometry on Human Blood Cells
Zhang, Z.; Yang, H.; Li, J.; Chong, S. W.; Eshraghian, J. K.; Yong, K.-T.; Vigolo, D.; McGuire, H.; Kavehei, O.
10.1101/2024.11.16.623904 — cell biology — Posted on 2024-11-18
2124 Neuromorphic Imaging Cytometry on Human Blood Cells
Zhang, Z.; Yang, H.; Li, J.; Chong, S. W.; Eshraghian, J. K.; Yong, K.-T.; Vigolo, D.; McGuire, H.; Kavehei, O.
10.1101/2024.11.16.623904 — cell biology — Posted on 2024-11-17
2126 The follicular lymphoma and chronic lymphocytic leukemia proliferative microenvironment at single-cell resolution
Ferreira, A. P.; Wang, S.; Poluben, L.; Brandstadter, J.; Perkey, E.; Sotirakos, S.; Drew, M.; Pan, L.; Lemieux, M. E.; Dorfman, D. M.; Shoji, B.; Maillard, I.; Blacklow, S. C.; Aster, J. C.
10.1101/2024.11.15.623868 — pathology — Posted on 2024-11-17
2127 Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding
Singh, S.; Gapsys, V.; Aldeghi, M.; Schaller, D.; Rangwala, A. M.; White, J. B.; Bluck, J. P.; Scheen, J.; Glass, W. G.; Guo, J.; Hayat, S.; de Groot, B. L.; Volkamer, A.; Christ, C. D.; Seeliger, M. A.; Chodera, J. D.
10.1101/2024.11.15.623861 — biophysics — Posted on 2024-11-17
2128 CellPatch: a Highly Efficient Foundation Model for Single-Cell Transcriptomics with Heuristic Patching
Wu, H.-J.; Zheng, X.; Ma, Z.; Zhu, H.; Yuan, Y.; Yang, J.; Cai, K.; Wei, N.; Zhang, S.; Wang, L.; Wenjie, J.; Sun, Y.; Wang, Y.-J.; Liu, A.; Lai, F.
10.1101/2024.11.15.623701 — bioinformatics — Posted on 2024-11-17
2130 The genome assembly of the westslope cutthroat trout, Oncorhynchus lewisi, reveals interspecific chromosomal rearrangements with the rainbow trout
Flores, A.-M.; Christensen, K. A.; Godin, T.; Palti, Y.; Campbell, M. R.; Waldbieser, G. C.; Simpson, S. A.; Scheffler, B. E.; Smith, S. R.; Whiteley, A. R.; Kovach, R. P.; Luikart, G.; Boyer, M. C.; Kardos, M.; Relyea, S.; Wells, C.; Koop, B. F.
10.1101/2024.11.15.623813 — genomics — Posted on 2024-11-17
2132 Microbiome Dynamics in Tank- and Pond-Reared GIFT Tilapia
Delamare-Deboutteville, J.; Mahmuddin, M.; Gan, H. M.; Rodde, C.; Khor, L.; Verner-Jeffreys, D.; Mohan Chadag, V.; Benzie, J. A. H.
10.1101/2024.11.16.622739 — microbiology — Posted on 2024-11-17
2133 Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer.
Panesso-Gomez, S.; Cole, A. J.; Wield, A.; Anyaeche, V. I.; Shah, J.; Jiang, Q.; Ebai, T.; Sharrow, A.; Tseng, G.; Yoon, E.; Brown, D. D.; Clark, A. M.; Larsen, S. D.; Eder, I.; Gau, D.; Roy, P.; Dahl, K. N.; Tran, L.; Jiang, H.; McAuliffe, P. F.; Lee, A.; Buckanovich, R.
10.1101/2024.11.15.623825 — cancer biology — Posted on 2024-11-17
2134 Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches
Chen, X.; Zhou, Z.; Yazgan, Z.; Xie, L.; Rossi, F.; Liu, Y.; Zhang, B.; Polanco, P. M.; Zeh, H. J.; Kim, A. C.; Huang, H.
10.1101/2024.11.15.623232 — cancer biology — Posted on 2024-11-17
2135 TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway
Guarnaccia, A. D.; Hagenbeek, T. J.; Lee, W.; Kljavin, N.; Choi, M.; Ulas, G.; Kameswaran, V.; Le, D.; Paul, S.; Vaidya, S.; Zbieg, J. R.; Crawford, J. J.; Daniel, B.; Dey, A.; Lill, J. R.
10.1101/2024.11.15.623512 — cancer biology — Posted on 2024-11-17
2137 Replicating dynamic immune responses at single-cell resolution within a microfluidic human skin equivalent
Hindle, S. A.; Bachas Brook, H.; Chrysanthou, A.; Chambers, E. S.; Caley, M. P.; Connelly, J. T.
10.1101/2024.11.15.623786 — bioengineering — Posted on 2024-11-17
2138 A single microfluidic device for multi-omics analysis sample preparation
Ravi Kumar, R. K.; Haddad, I.; Ndiaye, M. M.; Marbouty, M.; Vinh, J.; Verdier, Y.
10.1101/2024.11.17.624005 — biochemistry — Posted on 2024-11-17
2140 HSP90 buffers deleterious genetic variations in BRCA1
Gracia, B.; Montes, P.; Huang, M.; Chen, J.; Karras, G. I.
10.1101/2024.11.15.623783 — genetics — Posted on 2024-11-17
2141 Rapid wing size evolution in African fig flies (Zaprionus indianus) following temperate colonization
Gray, W. J.; Rakes, L. M.; Cole, C.; Gunter, A.; He, J.; Morgan, S.; Walsh-Antzak, C. R.; Yates, J. A.; Erickson, P. A.
10.1101/2024.11.15.623845 — evolutionary biology — Posted on 2024-11-17
2142 Nemo knows: clownfishes differentiate cryptic host species across fine and broad geographic scales and reveal a potential adaptive radiation in the clownfish-hosting sea anemones.
Chiodo, T.; De Jode, A.; Quattrini, A.; Gibson, M. K.; Froehlich, C. Y. M.; Huang, D.; Fujii, T.; Yanagi, K.; Reimer, J. D.; Scott, A.; Rodriguez, E.; Titus, B. M.
10.1101/2024.11.15.623784 — evolutionary biology — Posted on 2024-11-17
2144 Prey movement shapes the acquisition of predator expertise in a virtual bi-trophic system
Fraser Franco, M.; Santostefano, F.; Martin, J. G. A.; Kelly, C. D.; Montiglio, P.-O.
10.1101/2024.11.15.621573 — ecology — Posted on 2024-11-17
2148 Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages
Cortes-Martin, A.; Buttimer, C.; Maier, J.; Tobin, C. A.; Draper, L.; Ross, R. P.; Kleiner, M.; Hill, C.; Shkoporov, A. N.
10.1101/2024.11.17.624012 — microbiology — Posted on 2024-11-17
2149 Rhinovirus as a Driver of Airway T-Cell Dynamics in Children with Severe Asthma
Bryant, N.; Muehling, L. M.; Wavell, K.; Teague, W. G.; Woodfolk, J. A.
10.1101/2024.11.15.623877 — immunology — Posted on 2024-11-17
2150 An animal model for autoinflammation with infantile enterocolitis
Kang, Z.; Wang, Y.; Xiong, Y.; Gao, J. Z.; Gurung, P.; Short, S. P.
10.1101/2024.11.16.623944 — immunology — Posted on 2024-11-17
2152 IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity
naz, f.; Hagspiel,, N.; Young, M.; Uddin, M. J.; Tyus, D.; Boone, R.; Brown, A.; Ramakrishnan, G.; rigo, I.; Madden, G.; Petri, W. A.
10.1101/2024.11.16.623943 — immunology — Posted on 2024-11-17
2153 Identification of a Neuroimmune Circuit that Regulates Allergic Inflammation in the Esophagus
Kellerman, K.; Natale, M.; Gerstner, E.; Rochman, Y.; Rochman, M.; Jankowski, M. P.; Rothenberg, M.
10.1101/2024.11.16.623883 — immunology — Posted on 2024-11-17
2155 Glutamate receptor-dependent cytosolic acidification in hippocampal neurons involves passive flux of protons from the extracellular space
Pedersen, S. E.; Konomi-Pilkati, A.; Hansen, N. W.; Kvist, T.; Posselt, L. P.; Andreassen, T. F.; Sorensen, A. T.; Perrier, J.-F.; Madsen, k. L.
10.1101/2024.11.17.624027 — neuroscience — Posted on 2024-11-17
2157 Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes
Patinios, C.; Gupta, D.; Bassett, H. V.; Collins, S. P.; Kamm, C.; Kibe, A.; Wang, Y.; Zhao, C.; Vollen, K.; Toussaint, C.; Polkoff, K. M.; Nguyen, T.; Calvin, I.; Migur, A.; Al'Abri, I.; Achmedov, T.; del Re, A.; Saliba, A.-E.; Crook, N.; Stepanova, A. N.; Alonso, J. M.; Beisel, C. L.
10.1101/2024.11.17.623984 — synthetic biology — Posted on 2024-11-17
2162 Fast marching to branching morphologies
Kriuchechnikova, A. N.; Levdik, T. G.; Brazhe, A.
10.1101/2024.11.16.623917 — biophysics — Posted on 2024-11-17
2163 AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack
Wandera, K. G.; Schmelz, S.; Migur, A.; Kibe, A.; Lukat, P.; Achmedov, T.; Caliskan, N.; Blankenfeldt, W.; Beisel, C. L.
10.1101/2024.11.17.623997 — biochemistry — Posted on 2024-11-17
2165 Individual brain activity patterns during task are predicted by distinct resting-state networks that may reflect local neurobiological features
Scholz, R.; Benn, R. A.; Shevchenko, V.; Klatzmann, U.; Wei, W.; Alberti, F.; Chiou, R.; Zhang, X.-H.; Leech, R.; Smallwood, J.; Margulies, D. S.
10.1101/2024.11.13.621472 — neuroscience — Posted on 2024-11-17
2166 Population structure of the endangered Siberian flying squirrel (Pteromys volans) revealed by genomic and mitochondrial data
Ito dos Santos, F.; Lilley, T.; Laine, V. N.; Prost, S.; Kurhinen, J.; Susi, H.; Gashev, S.; Saveljev, A.; Bondarchuk, S.; Babina, S.; Shishikin, A.; Tirski, D.; Vasina, A.; Karpin, V.; Kekkonen, J. A.
10.1101/2024.09.13.612918 — evolutionary biology — Posted on 2024-11-17
2167 Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases
Erickson, A. G.; Isaev, S.; He, J.; Artemov, A. V.; Semsch, B.; Murtazina, A.; Sun, J.; Mangold, K.; Chalou, A.; Frisen, J.; Ratz, M.; Andersson, E. R.; Kharchenko, P. V.; Adameyko, I.
10.1101/2024.11.15.623687 — developmental biology — Posted on 2024-11-17
2168 A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope
Mannino, P. J.; Perun, A.; Surovstev, I.; Ader, N. R.; Shao, L.; Rodriguez, E. C.; Melia, T.; King, M. C.; Lusk, C. P.
10.1101/2024.02.14.580336 — cell biology — Posted on 2024-11-17
2169 p53 translational-isoform Δ 40p53 regulates cell cycle by modulating the miR-4671-5p/SGSH axis
Pal, A.; Ghosh, P. K.; Ghosh, S.; Tripathi, S. K.; Guha, S.; Coca, P.; Patra, S.; Prathima, K. M.; Khan, D.; Das, M.; Maitra, A.; Das, S.
10.1101/2023.04.04.535506 — molecular biology — Posted on 2024-11-17
2170 Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission and mortality in suckling neonates
Baker, P. H.; Moyer, M.; Bai, Y.; Stafford, L. S.; Kelvin, A. A.; Lee, C.; Kenney, S. P.; Langel, S. N.
10.1101/2024.11.15.623885 — microbiology — Posted on 2024-11-17
2173 CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning
Teter, O. M.; McQuade, A.; Hagan, V.; Liang, W.; Draeger, N. M.; Sattler, S. M.; Holmes, B. B.; Castillo, V. C.; Papakis, V.; Leng, K.; Boggess, S.; Nowakowski, T. J.; Wells, J.; Kampmann, M.
10.1101/2024.06.01.596962 — neuroscience — Posted on 2024-11-17
2174 Regulation of Fentanyl Reward in Male and Female Mice by the Circadian Transcription Factor NPAS2
Barko, K.; Shelton, M. A.; DePoy, L. M.; Gayden, J.; Kim, S.-M.; Puig, S.; Xue, X.; Oliver-Smith, J.; Zhu, X.; Parekh, P. K.; Tseng, G. C.; Williams, B.; Freyberg, Z.; Logan, R. W.
10.1101/2024.11.12.623242 — neuroscience — Posted on 2024-11-17
2179 Generalized cell phenotyping for spatial proteomics with language-informed vision models
Wang, X.; Dilip, R.; Bussi, Y.; Brown, C.; Pradhan, E.; Jain, Y.; Yu, K.; Li, S.; Abt, M.; Borner, K.; Keren, L.; Yue, Y.; Barnowski, R.; Van Valen, D. A.
10.1101/2024.11.02.621624 — bioinformatics — Posted on 2024-11-17
2182 sv-channels: filtering genomic deletions using one-dimensional convolutional neural networks
Santuari, L.; Georgievska, S.; Kuzniar, A.; Pedersen, B. S.; Shneider, C.; Mehrem, S.; Ridder, L.; Kloosterman, W. P.; de Ridder, J.
10.1101/2024.10.17.618894 — bioinformatics — Posted on 2024-11-17
2187 Genetically encoded fluorescent reporter for polyamines
Sharma, P.; Kim, C. Y.; Keys, H. R.; Imada, S.; Joseph, A. B.; Ferro, L.; Kunchok, T.; Anderson, R.; Yilmaz, O. H.; Weng, J.-K.; Jain, A.
10.1101/2024.08.24.609500 — cell biology — Posted on 2024-11-17
2188 Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
Yoon, J.; Liu, Z.; Alaba, M.; Bruggeman, L. A.; Janmey, P.; Arana, C.; Ayenuyo, O.; Medeiros, I.; Eddy, S.; Kretzler, M.; Henderson, J. M.; Nair, V.; Naik, A.; Chang, A. N.; Miller, R. T.
10.1101/2024.02.26.582201 — cell biology — Posted on 2024-11-17
2189 Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
Borodovich, T.; Wilson, J. S.; Bardy, P.; Smith, M.; Hill, C.; Khokhlova, E. V.; Govi, B.; Fogg, P. C.; Hill, C.; Shkoporov, A. N.
10.1101/2024.11.15.623857 — microbiology — Posted on 2024-11-17
2190 Lesions that Cause Psychosis Map to a Common Brain Circuit in the Hippocampus
Pines, A. R.; Frandsen, S. B.; Drew, W.; Meyer, G. M.; Howard, C.; Palm, S. T.; Schaper, F. L. W. V. J.; Lin, C.; Butenko, K.; Ferguson, M. A.; Friedrich, M. U.; Grafman, J. H.; Kappel, A. D.; Neudorfer, C.; Rost, N. S.; Sanderson, L. L.; Taylor, J. J.; Wu, O.; Kletenik, I.; Vogel, J. W.; Cohen, A. L.; Horn, A.; Fox, M. D.; Silbersweig, D.; Siddiqi, S. H.
10.1101/2024.04.28.591471 — neuroscience — Posted on 2024-11-17
2191 Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits
Pasquini, L.; Vohryzek, J.; Escrichs, A.; Sanz Perl, Y.; Ponce-Alvarez, A.; Idesis, S.; Girn, M.; Roseman, L.; Mitchell, J. M.; Gazzaley, A.; Kringelbach, M.; Nutt, D. J.; Lyons, T.; Carhart-Harris, R. L.; Deco, G.
10.1101/2024.11.06.622302 — neuroscience — Posted on 2024-11-17
2192 Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics
Xian, J.; He, Y.; Yan, Y.; Tian, X.; Peng, Y.; Lou, J.; Liu, X.; Wang, Q.; Gao, T.; Wang, Q.; Sun, Y.; Li, P.; Wang, Y.; Huang, S.; Li, K.; Hu, K.; Ding, C.; Li, D.; Wang, M.; Liu, B.; Li, A.
10.1101/2024.06.20.599966 — neuroscience — Posted on 2024-11-17
2193 Power-law adaptation in the presynaptic vesicle cycle
Mikulasch, F. A.; Georgiev, S. V.; Rudelt, L.; Rizzoli, S. O.; Priesemann, V.
10.1101/2024.07.19.604253 — neuroscience — Posted on 2024-11-17
2194 Cross-sectional brain age assessments are limited in predicting future brain change
Korbmacher, M.; Vidal-Pineiro, D.; Wang, M.-Y.; van der Meer, D.; Wolfers, T.; Nakua, H.; Eikefjord, E.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2024.09.11.612523 — neuroscience — Posted on 2024-11-17
2200 The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle
Günther, T.; Chisausky, J.; Galindo-Pellicena, M. A.; Iriarte, E.; Cortes Gardyn, O.; Eusebi, P. G.; Garcia-Gonzalez, R.; Urena, I.; Moreno, M.; Alday, A.; Rojo, M.; Perez, A.; Tejedor Rodriguez, C.; Garcia Martinez de Lagran, I.; Arsuaga, J. L.; Carretero, J.-M.; Götherström, A.; Smith, C.; Valdiosera, C.
10.1101/2023.07.19.548914 — genomics — Posted on 2024-11-17
2201 Microbial interactions affect the tempo and mode of antibiotic resistance evolution
Zandbergen, L. E.; van den Heuvel, J.; Farr, A. D.; Zwaan, B. J.; de Visser, A. J. G. M.; de Vos, M. G. J.
10.1101/2024.06.06.597700 — evolutionary biology — Posted on 2024-11-17
2206 A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite
Huang, L.; Liu, P.; Du, Y.; Bazan, J. F.; Pan, D.; Chen, Q.; Lee, A.; Rao Kola, V. S.; Wolfe, S.; Wang, Y.-X.
10.1101/2023.09.12.557454 — molecular biology — Posted on 2024-11-17
2207 Brainwide hemodynamics predict neural rhythms across sleep and wakefulness in humans
Jacob, L. P. L.; Bailes, S. M.; Williams, S. D.; Stringer, C.; Lewis, L. D.
10.1101/2024.01.29.577429 — neuroscience — Posted on 2024-11-17
2208 Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings
Dube, J.; Foti, M.; Jaffard, S.; Latreille, V.; Frauscher, B.; Carrier, J.; Lina, J. M.
10.1101/2024.10.28.620621 — neuroscience — Posted on 2024-11-17
2209 Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity
O'Toole, K.; Guetta, L.; Urbanaviciute, P.; Suklai, P.; Wright, C.; Fisher, T.; Liddelow, S.; Luisier, R.; Marzi, S. J.; Serio, A.
10.1101/2024.11.11.622998 — neuroscience — Posted on 2024-11-17
2210 Ethylene Receptor Gain- and Loss-of-function Mutants Reveal an ETR1-dependent Transcriptional Network in Roots
Khoury, M. G.; Harkey, A.; Muhlemann, J. K.; Olex, A. L.; Houben, M.; Binder, B.; Muday, G. K.
10.1101/2024.06.26.600793 — plant biology — Posted on 2024-11-17
2222 Novel Library Assembly Technique for Developing Nanobodies Targeting IPNv VP2 Protein
Pino-Belmar, C.; Himelreichs, J.; Deride, C.; Matute, T.; Nunez, I.; Cazaux, S.; Federici, F.; Moreno, K.; Soto Rauch, G.; Munizaga, J.; Haussmann, D.; Rojas-Fernandez, A.; Figueroa, J.; Valenzuela-Nieto, G. E.
10.1101/2024.11.13.623509 — molecular biology — Posted on 2024-11-17
2223 Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis
Keller, M. R.; Soni, V.; Brown, M.; Rosch, K. M.; Saleh, A.; Rhee, K. Y.; Dörr, T.
10.1101/2024.11.13.623475 — microbiology — Posted on 2024-11-17
2224 Trans-Translation inhibitors and copper ions synergize for enhanced antibiotic activity
Vazquez-Hernandez, M.; Uzun, H. D.; Otte, M.; Schipp, L.; Senges, C. H. R.; Heinrich, S.; Alumasa, J. N.; Stepien, J.; Demirbas, F.; Cignoni, P.; Marcus, K.; Tschulik, K.; Krämer, U.; Keiler, K. C.; Günther Pomorski, T.; Bandow, J. E.
10.1101/2024.11.14.623546 — microbiology — Posted on 2024-11-17
2228 Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.
Katz, L. S.; Visser, E. J.; Plitzko, K. F.; Pennings, M.; Cossar, P. J.; Tse, I. L.; Kaiser, M.; Brunsveld, L.; Ottmann, C.; Scott, D. K.
10.1101/2024.02.16.580675 — cell biology — Posted on 2024-11-17
2230 Non-genetic adaptation by collective migration
Vo, L.; Avgidis, F.; Mattingly, H.; Edmonds, K.; Burgers, I.; Balasubramanian, R.; Shimizu, T. S.; Kazmierczak, B. I.; Emonet, T.
10.1101/2024.01.02.573956 — systems biology — Posted on 2024-11-17
2232 Natural variations of TaMYB7-A1 regulate PHS resistance and specify wheat geographic adaptation
Wang, H.; Wang, D.; Guo, Y.; Zhang, M.; Simmonds, J.; Zheng, Q.; Hou, J.; Liu, X.; Lin, X.; Bie, X.; Zhang, X.; Zhang, X.; Uauy, C.; Lu, F.; Chu, C.; Tian, Z.; Xiao, J.
10.1101/2024.11.15.623828 — plant biology — Posted on 2024-11-17
2233 The conserved aphid saliva chemosensory protein effector Mp10 targets plant AMSH deubiquitinases at cellular membranes to suppress pattern-triggered immunity
Gravino, M.; Mugford, S. T.; Kreuter, N.; Joyce, J.; Wilson, C.; Kliot, A.; Canham, J.; Mathers, T. C.; Drurey, C.; Maqbool, A.; Saalbach, G.; Martins, C.; Hogenhout, S. A.
10.1101/2024.11.15.622802 — plant biology — Posted on 2024-11-17
2238 Heat Shock Factor 1 Governs Sleep-Wake Cycles Across Species
Yamazaki, S.; Valekunja, U. K.; Chen-Roetling, J.; Reddy, A. B.
10.1101/2024.11.15.623879 — neuroscience — Posted on 2024-11-17
2239 Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
Güth, M. R.; Reid, A.; Zhang, Y.; Huntgeburth, S. C.; Mill, R. D.; Dagher, A.; Kerns, K.; Holroyd, C. B.; Petrides, M.; Cole, M. W.; Baker, T. E.
10.1101/2024.11.16.623803 — neuroscience — Posted on 2024-11-17
2240 Combining NeuroPainting with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion
Tegtmeyer, M.; Liyanage, D.; Han, Y.; Hebert, K.; Pei, R.; Way, G. P.; Ryder, P. V.; Hawes, D.; Tromans-Coia, C.; Cimini, B. A.; Carpenter, A. E.; Singh, S.; Nehme, R.
10.1101/2024.11.16.623947 — neuroscience — Posted on 2024-11-17
2241 ASAP: An automatic sustained attention prediction method for infants and toddlers using wearable device signals
Zhang, Y.; Martinez-Cedillo, P. A.; Mason, H. T.; Vuong, Q. C.; Garcia-de-Soria, M. C.; Mullineaux, D. R.; Knight, M. I.; Geangu, E.
10.1101/2024.11.16.623211 — neuroscience — Posted on 2024-11-17
2242 Whole-brain causal connectivity during decoded neurofeedback: a meta study
Arab, F.; Ghassami, A.; Jamalabadai, H.; Peters, M. A. K.; Nozari, E.
10.1101/2024.11.16.623939 — neuroscience — Posted on 2024-11-17
2243 Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases
Erickson, A. G.; Isaev, S.; He, J.; Artemov, A. V.; Semsch, B.; Murtazina, A.; Sun, J.; Mangold, K.; Chalou, A.; Frisen, J.; Ratz, M.; Andersson, E. R.; Kharchenko, P. R.; Adameyko, I. I.
10.1101/2024.11.15.623687 — developmental biology — Posted on 2024-11-17
2244 Reconstitution of Human Brain Cell Diversity in Organoids via Four Protocols
Naas, J.; Balmana, M.; Holcik, L.; Novatchkova, M.; Dobnikar, L.; Krausgruber, T.; Ladstatter, S.; Bock, C.; von Haeseler, A.; Esk, C.; Knoblich, J. A.
10.1101/2024.11.15.623576 — developmental biology — Posted on 2024-11-17
2249 Dynamic cytoplasmic fluidity during morphogenesis in a human fungal pathogen
Serrano, A.; Puerner, C.; Plumb, E.; Chevalier, L.; Elferich, J.; Sinn, L. R.; Grigorieff, N.; Ralser, M.; Delarue, M.; Bassilana, M.; Arkowitz, R. A.
10.1101/2024.11.16.623909 — cell biology — Posted on 2024-11-17
2252 Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice
Li, Y.; Ji, C.-y.; Zhang, Y.-f.; Lin, Z.-y.; Zhao, Z.-q.; Jiao, Z.-l.; Zheng, Z.-y.; Shi, X.-x.; Wang, X.-f.; Li, Z.-y.; Yu, S.-s.; Qu, Y.; Wei, Y.; Zheng, B.; Shi, H.-y.; Wang, Q.-f.; Sandoval, A.; Chen, B.; Yu, X.; Xu, X.-h.; Poo, M.-m.; Chen, J.-x.; Cai, W.-h.
10.1101/2024.11.16.621796 — neuroscience — Posted on 2024-11-17
2253 Modality-Specific and Amodal Language Processing by Single Neurons
Yair, L.; Friedmann, N.; King, J.-R.; Mankin, E.; Rangel, A.; Tankus, A.; Dehaene, S.; Fried, I.
10.1101/2024.11.16.623907 — neuroscience — Posted on 2024-11-17
2256 Brain-region-specific changes and dysregulation of activity regulated genes in Gria3 mutant mice, a genetic animal model of schizophrenia
Huang, W.-C.; Kast, R.; Mandell, K. P.; Dejanovic, B.; Bonanno, K.; Aryal, S.; Farsi, Z.; Wilde, J.; Wang, D.; Gao, X.; Keshishian, H.; Carr, S. A.; Feng, G.; Sheng, M.
10.1101/2024.11.15.623468 — neuroscience — Posted on 2024-11-17
2257 A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo
Villette, V.; Yang, S.; Valenti, R.; Macklin, J. J.; Bradley, J.; Mathieu, B.; Lombardini, A.; Podgorski, K.; Dieudonne, S.; Schreiter, E. R.; Abdelfattah, A. S.
10.1101/2024.11.15.623698 — neuroscience — Posted on 2024-11-17
2262 Diverse quorum sensing systems regulate microbial communication and biogeochemical processes in deep-sea cold seeps
Peng, J.; Liu, X.; Wang, J.; Meng, N.; Cai, R.; Peng, Y.; Han, Y.; Liao, J.; Rubin-Blum, M.; Li, C.; Ma, Q.; Dong, X.
10.1101/2024.11.15.623595 — microbiology — Posted on 2024-11-16
2266 Design of facilitated dissociation enables control over cytokine signaling duration
Broerman, A. J.; Pollmann, C.; Lichtenstein, M. A.; Jackson, M. D.; Tessmer, M. H.; Ryu, W. H.; Abedi, M. H.; Sahtoe, D. D.; Allen, A.; Kang, A.; De La Cruz, J.; Brackenbrough, E.; Sankaran, B.; Bera, A. K.; Zuckerman, D. M.; Stoll, S.; Praetorius, F.; Piehler, J.; Baker, D.
10.1101/2024.11.15.623900 — biochemistry — Posted on 2024-11-16
2270 Immunization with Plant-based Vaccine Expressing Toxoplasma gondii SAG1 Fused to Plant HSP90 Elicits Protective Immune Response in Lambs
Campero, L. M.; Gual, I.; Sander, V. A.; Mendoza-Morales, L. F.; Ramos-Duarte, V. A.; Formigo, P.; Sosa, E.; Lazaro, F.; Scioli, M. V.; Atela, A.; Legarralde, A.; Hozbor, F.; Canton, G.; Angel, S. O.; Moore, D.; Clemente, M.
10.1101/2024.11.15.623790 — molecular biology — Posted on 2024-11-16
2272 The mitochondrial methylation potential gates mitoribosome assembly
Glasgow, R. I. C.; Singh, V.; Pena-Perez, L.; Wilhalm, A.; Moedas, M. F.; Moore, D.; Rosenberger, F. A.; Li, X.; Atanassov, I.; Saba, M.; Cipullo, M.; Rorbach, J.; Wedell, A.; Freyer, C.; Amunts, A.; Wredenberg, A.
10.1101/2024.11.15.623401 — molecular biology — Posted on 2024-11-16
2273 Calmodulin acts as a chaperone during co-translational folding of the Kv7.2 channel Calcium Responsive Domain.
Muguruza-Montero, A.; R. Tait, J.; M-Alicante, S.; Metola, A.; Nunez, E.; Urrutia, J.; Sunderlikov, V.; Katranidis, A.; von Heijne, G.; J. Tans, S.; Villarroel, A.
10.1101/2024.11.15.622191 — molecular biology — Posted on 2024-11-16
2274 Mapping Pesticide-Induced Metabolic Alterations in Human Gut Bacteria
Chen, L.; Yan, H.; Di, S.; Guo, C.; Zhang, H.; Zhang, S.; Gold, A.; Wang, Y.; Hu, M.; Johnson, C. H.; Wang, X.; Zhu, J.
10.1101/2024.11.15.623895 — microbiology — Posted on 2024-11-16
2275 Oropouche virus infects human placenta explants and trophoblast organoids
Megli, C.; Zack, R. K.; McGaughey, J.; Hoehl, R. M.; Snisky, T.; Hartman, A. L.; McMillen, C.
10.1101/2024.11.16.623866 — microbiology — Posted on 2024-11-16
2276 Metabolomic Analysis of Murine Tissues Infected with Brucella melitensis
Ponzilacqua-Silva, B.; Dadelahi, A. S.; Moley, C. R.; Abushahba, M. F. N.; Skyberg, J.
10.1101/2024.11.16.623915 — microbiology — Posted on 2024-11-16
2280 Arv1 interacts with and regulates the first step of GPI biosynthesis in Candida albicans
Komath, S. S.; Bharati, M.; Saini, H.; Thakran, N.; Kumar, Y.; Yadav, U.; Shefali, S.; Anzar, A.; Saun, S.
10.1101/2024.11.16.623920 — microbiology — Posted on 2024-11-16
2282 Bovine H5N1 influenza virus infection is transmitted by milk causing mortality in suckling neonates
Baker, P. H.; Moyer, M. N.; Bai, Y. N.; Stafford, L. S.; Kelvin, A. A.; Lee, C.; Kenney, S. P.; Langel, S. N.
10.1101/2024.11.15.623885 — microbiology — Posted on 2024-11-16
2284 Targeted protein evolution in the gut microbiome by diversity-generating retroelements
Macadangdang, B. R.; Wang, Y.; Woodward, C.; Revilla, J. I.; Shaw, B. M.; Sasaninia, K.; Makanani, S. K.; Berruto, C.; Miller, J. F.
10.1101/2024.11.15.621889 — microbiology — Posted on 2024-11-16
2286 Contribution of ammonia oxidizers to inorganic carbon fixation in the dark ocean
Bayer, B.; Kitzinger, K.; Paul, N. L.; Albers, J. B.; Saito, M. A.; Wagner, M.; Carlson, C. A.; Santoro, A. E.
10.1101/2024.11.16.623942 — microbiology — Posted on 2024-11-16
2288 Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
Borodovich, T.; Wilson, J. S.; Bardy, P.; Smith, M.; Hill, C.; Khokhlova, E. V.; Govi, B.; Fogg, P. C.; Hill, C.; Shkoporov, A. N.
10.1101/2024.11.15.623857 — microbiology — Posted on 2024-11-16
2289 Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19
Maguire, C.; Chen, J.; Rouphael, N.; Pickering, H.; Phan, H. V.; Glascock, A.; Chu, V.; Dandekar, R.; Corry, D.; Kheradmand, F.; Baden, L. R.; Selaky, R.; McComsey, G. A.; Haddad, E. K.; Cairns, C. B.; Pulendran, B.; Fernandez-Sesma, A.; Simon, V.; Metcalf, J. P.; Higuita, N. I. A.; Messer, W. B.; David, M. M.; Nadeau, K. C.; Kraft, M.; Bime, C.; Schaenman, J.; Erle, D.; Calfee, C. S.; Atkinson, M. A.; Brackenridge, S. C.; Ehrlich, L. I. R.; Montgomery, R. R.; Shaw, A. C.; Hough, C. L.; Geng, L. N.; Hafler, D. A.; Augustine, A. D.; Becker, P. M.; Peters, B.; Ozonoff, A.; Kim-Schulze, S. H.; Kr
10.1101/2024.11.14.622799 — immunology — Posted on 2024-11-16
2291 PrP turnover in vivo and the time to effect of prion disease therapeutics
Corridon, T. L.; OMoore, J.; Lian, Y.; Laversenne, V.; Noble, B.; Kamath, N. G.; Serack, F. E.; Shaikh, A. B.; Erickson, B.; Braun, C.; Lenz, K.; Howard, M.; Chan, N.; Reidenbach, A. G.; Cabin, D. E.; Vallabh, S. M.; Grindeland, A.; Oberbeck, N.; Zhao, H. T.; Minikel, E. V.
10.1101/2024.11.12.623215 — neuroscience — Posted on 2024-11-16
2297 Chemogenetic Breakdown of the Dentate Gate Causes Seizures and Spatial Memory Deficits
Adam, C. D.; Schellinger, E. D.; White, A.; Joksimovic, S. M.; Takano, H.; Coulter, D. A.
10.1101/2024.11.12.623184 — neuroscience — Posted on 2024-11-16
2298 Heat Acclimation in Mice Requires Preoptic BDNF Neurons and Postsynaptic Potentiation
Chen, B.; Gao, C.; Liu, C.; Guo, T.; Hu, J.; Xue, J.; Tang, K.; Chen, Y.; Yu, T.; Shen, Q.; Sun, H.; Yang, W. Z.; Shen, W.
10.1101/2024.11.13.623142 — neuroscience — Posted on 2024-11-16
2299 Type I interferon signaling enhances kainic acid-induced seizure severity
Ma, J.-H.; Eo, J.-C.; Lee, C.; Hwang, I.; Choi, J.; Shin, S. J.; Kim, C. H.; Yu, J.-W.
10.1101/2024.11.13.623521 — neuroscience — Posted on 2024-11-16
2300 WMH-DualTasker: A Dual-Task Deep Learning Model with Self-supervised Consistency for Automated Segmentation and Visual Rating of White matter Hyperintensities - a Multicentre study
Wu, Y.; Dong, Z.; Li, H. B.; Chong, Y. F.; Ji, F.; Xian Chong, J. S.; Jie Tang, N. R.; Hilal, S.; Fu, H.; Chen, C. L.-H.; Zhou, J. H.; Alzheimers Disease Neuroimaging Initiative,
10.1101/2024.11.12.623137 — neuroscience — Posted on 2024-11-16
2301 Sortilin C-terminal fragment deposition depicts tangle-related nonamyloid neuritic plaque growth in Alzheimers disease
Zhang, Q.-L.; Wang, Y.; Coulibaly, S.; Sun, Z.-P.; Cai, X.-L.; Tu, T.; Liu, Y.; Pan, A.; Cui, M.-C.; Manavis, J.; Wang, J.; Zhang, Y.; Wang, X.-P.; Yan, X.-X.
10.1101/2024.11.11.622955 — neuroscience — Posted on 2024-11-16
2305 Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancer
Cheng, Y.-Y.; Worley, B. L.; Javed, Z.; Elhaw, A. T.; Tang, P. W.; Al-Saad, S.; Kamlapurkar, S.; White, S. R.; Uboveja, A.; Mythreye, K.; Aird, K. M.; Czyzyk, T. A.; Hempel, N.
10.1101/2024.11.14.623672 — cancer biology — Posted on 2024-11-15
2306 Pan-Cancer Drug Sensitivity Prediction from Gene Expression using Deep Learning
Ocasio, B. A.; Hu, J.; Stathias, V.; Martinez, M. J.; Burnstein, K. L.; Schurer, S. C.
10.1101/2024.11.15.623715 — bioinformatics — Posted on 2024-11-15
2307 Pangenome References Improve Biomarker Estimation from Tumor Sequencing Data
Arslan, E.; Turgut, D.; Kalay, O.; Demirkaya-Budak, S.; Budak, G.; Jain, A.
10.1101/2024.11.14.623554 — bioinformatics — Posted on 2024-11-15
2309 Disordered glass nanowire substrates produce in vivo-like astrocyte morphology revealed by optical diffraction tomography
Anantha, P.; Kim, J. H.; Saracino, E.; Raj, P.; Lucarini, I.; Tanwar, S.; Chen, J.; Gu, L.; Agrawal, J.; Convertino, A.; Barman, I.
10.1101/2024.11.14.623676 — cell biology — Posted on 2024-11-15
2310 Polysomes and mRNA control the biophysical properties of the eukaryotic cytoplasm
Gade, V. R.; Heinrich, S.; Paloni, M.; Gomez-Garcia, P. A.; Dzanko, A.; Oswald, A.; Marchand, D.; Khawaja, S.; Barducci, A.; Weis, K.
10.1101/2024.11.14.623620 — cell biology — Posted on 2024-11-15
2312 Alternative cGAS signaling promotes Herpes simplex encephalitis
Shmuel-Galia, L.; Jiang, Z.; Stine, L.; Cahill, S.; Ng, S.-l.; Wilson, R.; Kandasamy, R. K.; Kurt-Jones, E.; Ramanjulu, J.; Bertin, J.; Kasparcova, V.; Pesiridis, S.; Fitzgerald, K. A.; Humphries, F.
10.1101/2024.11.15.623778 — immunology — Posted on 2024-11-15
2313 T cell receptor sharing in hypersensitivity pneumonitis
Sendama, W.; Funston, W.; Davidson, R. C.; Rostron, A. J.; Simpson, A. J.
10.1101/2024.11.13.623392 — immunology — Posted on 2024-11-15
2314 Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis in mice
Jaerke, L.; Weber-Stiehl, S.; Shima, K.; Moors, K. A.; Genth, J.; Schuran, F. A.; Best, L.; Tschurtschenthaler, M.; Flemer, B.; Tholey, A.; Kaleta, C.; Rupp, J.; Rosenstiel, P.; Sommer, F.
10.1101/2024.11.15.623798 — cancer biology — Posted on 2024-11-15
2321 PRC1 and CTCF-Mediated Transition from Poised to Active Chromatin Loops Drives Bivalent Gene Activation
Hanafiah, A.; Geng, Z.; Liu, T.; Tai, Y. T.; Cai, W.; Wang, Q.; Christensen, N.; Liu, Y.; Yue, F.; Gao, Z.
10.1101/2024.11.13.623456 — genomics — Posted on 2024-11-15
2323 Urban tree diversity fosters bird insectivory despite a loss in bird diversity with urbanization
Schille, L.; Paquette, A.; Marcotte, G.; Ouellet, H.; Cobus, S.; Barbaro, L.; Castagneyrol, B.
10.1101/2024.11.15.623789 — ecology — Posted on 2024-11-15
2324 A novel class of allosteric glucosylceramidase beta 1 correctors that reduce cellular stress and enhance lysosomal function
Fregno, I.; Perez-Carmona, N.; Rudinskiy, M.; Solda, T.; Bergmann, T. J.; Ruano, A.; Delgado, A.; Cubero, E.; Bellotto, M.; Garcia-Collazo, A. M.; Molinari, M.
10.1101/2024.11.15.623779 — cell biology — Posted on 2024-11-15
2330 Inflammation-associated monocytes express ACOD1 to curtail inflammatory behaviour in IBD and experimental colitis
Jones, G.-R.; Drury, B.; Alegbe, T.; Krzak, M.; Hegarty, L.; Raine, T.; Byrne, A.; Anderson, C.; Ho, G.-T.; Bain, C. C.
10.1101/2024.11.15.623347 — immunology — Posted on 2024-11-15
2331 Anti-HIV-1 B cell antigen receptor signaling and structure
Thakur, B.; Alam, J.; Cronin, K.; Patel, P.; Anasti, K.; Pai Kane, A.; Hossain, A.; Do, H. N.; Mansouri, K.; Spence, T. N.; Edwards, R. J.; Janowska, K.; Lella, M.; Cook, A.; Saunders, K. O.; Gnanakaran, S.; Haynes, B. F.; Acharya, P.; Alam, S. M.
10.1101/2024.11.15.623645 — immunology — Posted on 2024-11-15
2332 Digitally immune optimised haemagglutinin with nanocage plug-and-display elicits broadly neutralising pan-H5 influenza subtype vaccine responses
Huang, C. Q.; Hills, R. A.; Carnell, G. W.; Vishwanath, S.; Aguinam, E. T.; Chan, A. C. Y.; Palmer, P.; O'Reilly, L.; Tonks, P.; Temperton, N.; Frost, S. D. W.; Tiley, L. S.; Howarth, M. R.; Heeney, J. L.
10.1101/2024.11.14.623359 — immunology — Posted on 2024-11-15
2333 Semaglutide-induced weight loss improves mitochondrial energy efficiency in skeletal muscle
Choi, R. H.; Karasawa, T.; Meza, C. A.; Maschek, J. A.; Manuel, A.; Nikolova, L. S.; Fisher-Wellman, K. H.; Cox, J.; Chaix, A.; Funai, K.
10.1101/2024.11.13.623431 — physiology — Posted on 2024-11-15
2334 Peroxidasin expression is increased in intratumoural capillaries and in proximal tubular cells adjacent to clear cell renal cell carcinoma.
Pestana e Silva, R. N.; Almeida, J. R.; Coelho, A. R.; Brandao, I.; Gomes, B.; Alencastre, I.; Oliveira, J. P.
10.1101/2024.11.15.623667 — pathology — Posted on 2024-11-15
2335 Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems
Park, V. S.; Pope, L. E.; Ingram, J.; Alchemy, G. A.; Purkal, J.; Andino-Frydman, E. Y.; Jin, S.; Singh, S.; Chen, A.; Narayanan, P.; Kongpachith, S.; Phillips, D. C.; Dixon, S. J.; Popovic, R.
10.1101/2024.11.14.622381 — cancer biology — Posted on 2024-11-15
2338 Language model-guided anticipation and discovery of unknown metabolites
Qiang, H.; Wang, F.; Lu, W.; Xing, X.; Kim, H.; Merette, S. A. M.; Ayres, L. B.; Oler, E.; AbuSalim, J. E.; Roichman, A.; Neinast, M.; Cordova, R. A.; Lee, W. D.; Herbst, E.; Gupta, V.; Neff, S.; Hiebert-Giesbrecht, M.; Young, A.; Gautam, V.; Tian, S.; Wang, B.; Rost, H.; Greiner, R.; Chen, L.; Johnston, C. W.; Foster, L. J.; Shapiro, A. M.; Wishart, D. S.; Rabinowitz, J. D.; Skinnider, M. A.
10.1101/2024.11.13.623458 — bioinformatics — Posted on 2024-11-15
2339 TSniffer: Unbiased de novo identification of RNA editing sites and quantification of editing activity in RNA-seq data
Herrmann, M.; Krebs, Y.; Acosta, F. M.; Parusel, S.; Siering, O.; Andres, F. G.; Taye, B.; Miskey, C.; Pfaller, C. K.
10.1101/2024.11.13.621086 — bioinformatics — Posted on 2024-11-15
2341 Anubis: a multi-level authentication scale for ancient proteins using random forest classification
Chiang, Y.; Nair, B. A. B.; Ramsoe, M. E. E.; Ravnsborg, T.; Jensen, O. N.; Collins, M. J.
10.1101/2024.11.15.623824 — bioinformatics — Posted on 2024-11-15
2345 Clickable PEG-norbornene microgels support suspension bioprinting and microvascular assembly
Zhang, I. W.; Choi, L. S.; Friend, N. E.; McCoy, A. J.; Midekssa, F. S.; Alsberg, E.; Lesher-Perez, S. C.; Stegemann, J. P.; Baker, B. M.; Putnam, A. J.
10.1101/2024.11.15.623424 — bioengineering — Posted on 2024-11-15
2346 Telomeric Repeat-Containing RNA Increases in Aged Human Cells
Chu, H.-P. C.; Hsieh, Y.-H.; Tai, C.-H.; Yeh, M.-T.; Yang, P.-C.; Chen, Y.-C.; Yen, C.-P.; Han, D.-S.
10.1101/2024.11.14.623513 — genomics — Posted on 2024-11-15
2347 Illumina Complete Long Read Assay yields contiguous bacterial genomes from human gut metagenomes
Maghini, D. G.; Darling, A. E.; Monahan, L.; Halpern, A.; Burke, C. M.; Jaeger, E.; Statham, A.; Truong, T.; Ying, K.; Schroth, G.; Bhatt, A. S.
10.1101/2024.11.15.623807 — genomics — Posted on 2024-11-15
2349 Steroid receptor-assisted loading modulates transcriptional responses in prostate cancer cells
Hiltunen, J.; Helminen, L.; Aaltonen, N.; Launonen, K.-M.; Laakso, H.; Malinen, M.; Niskanen, E. A.; Palvimo, J. J.; Paakinaho, V.
10.1101/2024.11.15.623719 — genomics — Posted on 2024-11-15
2350 LIN-35 and the DREAM complex promote temperature stress induced increases in germline apoptosis and cytoplasmic streaming in C. elegans
Petrella, L. N.; Compere, F. V.; Quaglia, K. A.; Crespo Cruz, M. N.; Lorenzen, H. N.; Oswald, S. H.; Uttal, K.
10.1101/2024.11.13.623436 — genetics — Posted on 2024-11-15
2353 Visual physiology of Australian stingless bees
Penmetcha, B.; Ryan, L. A.; Ogawa, Y.; Hart, N. S.; Narendra, A.
10.1101/2024.11.14.623562 — evolutionary biology — Posted on 2024-11-15
2357 Optimized recess design in artificial structures dramatically enhances coral settlement and survival
Reichert, J.; Jorissen, H.; Drury, C.; Hancock, J.; Haynes, C.; Nims, A.; Rova, L. H.; Schiettekatte, N. M.; R3D Consortium, ; Madin, J. S.
10.1101/2024.11.14.623685 — ecology — Posted on 2024-11-15
2359 TUDCA modulates drug bioavailability to regulate resistance to acute ER stress in Saccharomyces cerevisiae
Chadwick, S. R.; Stack-Couture, S.; Berg, M. D.; Di Gregorio, S. E.; Lung, B.; Genereaux, J.; Moir, R. D.; Brandl, C. J.; Willis, I. M.; Snapp, E.; Lajoie, P.
10.1101/2024.11.14.623614 — cell biology — Posted on 2024-11-15
2361 Dynamic change of calcium-rich compartments during coccolithophore biomineralization
Triccas, A.; Chevrier, D. M.; Verezhak, M.; Ihli, J.; Guizar-Sicairos, M.; Holler, M.; Scheffel, A.; Ozaki, N.; Chamard, V.; Wood, R.; Grunewald, T. A.; Nudelman, F.
10.1101/2024.11.15.623571 — cell biology — Posted on 2024-11-15
2364 Integrated proteome and lipidome analyses place OCIAD1 at mitochondria-peroxisome intersection balancing lipid metabolism
Linke, V.; Chodkowski, M.; Kaszuba, K.; Radkiewicz, M.; Rana, V.; Stadnik, D.; Dadlez, M.; Chacinska, A.
10.1101/2024.11.15.623757 — cell biology — Posted on 2024-11-15
2366 Dietary Restriction Enhances CD8+ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity
Oswald, B. M.; DeCamp, L. M.; Longo, J.; Dahabieh, M. S.; Bunda, N.; Ma, S.; Watson, M. J.; Sheldon, R.; Vincent, M. P.; Johnson, B. K.; Ellis, A. E.; Soper-Hopper, M. T.; Isaguirre, C. N.; Shen, H.; Williams, K. S.; Crawford, P. A.; Kaech, S.; Jang, H. J.; Krawczyk, C. M.; Jones, R.
10.1101/2024.11.14.621733 — immunology — Posted on 2024-11-15
2367 Canonical Notch2 Signaling Regulates the Development of Iron-recycling Macrophages and Iron Homeostasis
Schroth, F. N.; Kapanadze, T.; Sablotny, S.; Xu, Y.; Chung, B. M.; Deuper, L.; Kispert, A.; Lochner, M.; Kempf, T.; Haller, H.; Schmidt-Ott, K. M.; Gamrekelashvili, J.; Limbourg, F.
10.1101/2024.11.13.622461 — immunology — Posted on 2024-11-15
2370 A reconstruction of the mammalian secretory pathway identifies mechanisms regulating antibody production
Masson, H.; Tat, J.; Di Giusto, P.; Antonakoudis, A.; Shamie, I.; Baghdassarian, H.; Samoudi, M.; Robinson, C. M.; Kuo, C.-C.; Koga, N.; Singh, S.; Gezalyan, A.; Li, Z.; Movsessian, A.; Richelle, A.; Lewis, N. E.
10.1101/2024.11.14.623668 — systems biology — Posted on 2024-11-15
2371 OPN5 and TRPV4 subserve intrinsic photosensitivity in mouse corneal epithelium
Lapajne, L.; Lakk, M. A.; Rudzitis, C. N.; Vemaraju, S.; Lang, R. A.; Hawlina, M.; Krizaj, D.
10.1101/2024.11.14.623473 — physiology — Posted on 2024-11-15
2372 Tissue clocks derived from histological signatures of biological aging enable tissue-specific aging predictions from blood
Abila, E.; Buljan, I.; Zheng, Y.; Veres, T.; Weng, Z.; Nackenhorst, M. C.; Hulla, W.; Tolkach, Y.; Woehrer, A.; Rendeiro, A. F.
10.1101/2024.11.14.618081 — physiology — Posted on 2024-11-15
2374 Fibroblast-derived osteoglycin promotes epithelial cell repair
van der Koog, L.; Woest, M. E.; Gorter, I. C.; Verschut, V.; Elferink, R. A. B.; Zuidhof, A. B.; Nugraha, D. F.; Koloko Ngassie, M. L.; Bos, S. I. T.; Dhakad, D.; Wolters, J. C.; Horvatovich, P. L.; Prakash, Y. S.; Timens, W.; Yildirim, O. A.; Brandsma, C.-A.; Frijlink, H. W.; Nagelkerke, A.; Gosens, R.
10.1101/2024.11.14.623606 — pharmacology and toxicology — Posted on 2024-11-15
2375 Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis
Wu, B. R.-L.; Lively, S. S.; Fine, N.; Pastrello, C.; Maglaviceanu, A.; Espin-Garcia, O.; Pollock-Tahiri, E.; Nakamura, S.; Kaur, P.; Rockel, J.; Potla, P.; Gupta, H.; Datta, P.; Tang, L.; Vohra, S.; Nakamura, A.; Gandhi, R.; Wu, J.; Hinz, B.; Jurisica, I.; Kapoor, M.
10.1101/2024.11.14.622787 — pathology — Posted on 2024-11-15
2376 ecPath detects ecDNA in tumors from histopathology images
Choudhury, M.; Liu, L.; Yadav, A.; Chapman, O. S.; Ahmadi, Z.; Younis, R.; Sharma, C.; Goel, N.; Sridhar, S.; Kenkre, R.; Dutta, A.; Wang, S.; Shulman, E.; Dhruba, S. R.; Tai, H. D.; Tharp, K.; Paul, M.; Malicki, D.; Yip, K.; Ruppin, E.; Chavez, L.; Sinha, S.
10.1101/2024.11.13.623494 — pathology — Posted on 2024-11-15
2378 Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration
Lado-Fernandez, P.; Vilas, J. M.; Fernandes, T.; Carneiro, C.; Da Silva-Alvarez, S.; Estevez-Souto, V.; Pedrosa, P.; Gonzalez-Barcia, M.; Abatti, L. E.; Mitchell, J. A.; Rivas, C.; Moreno-Bueno, G.; Vidal, A.; Collado, M.
10.1101/2024.11.14.623640 — cancer biology — Posted on 2024-11-15
2380 Whole-Slide ECM Imaging Reveals Dense Fibrous Matrix as a High-Risk Factor for Recurrence in Stage II Colon Cancer
Ravensbergen, C.; Colaco, V.; Putter, H.; Crobach, S.; Boonstra, J.; Lindeman, J.; Tollenaar, R.; Mesker, W.
10.1101/2024.11.14.622985 — cancer biology — Posted on 2024-11-15
2381 Quantifying Cell Traction Forces at the Individual Fiber Scale in 3D: A Novel Approach Based on Deformable Photopolymerized Fiber Arrays
Ucla, P.; Le Chesnais, J.; Ver Hulst, H.; Ju, X.; Calvente, I.; Leconte, L.; Salamero, J.; Bonnet, I.; Monnot, C.; Moreau, H. D.; Landoulsi, J.; Semetey, V.; Coscoy, S.
10.1101/2024.11.14.623421 — biophysics — Posted on 2024-11-15
2383 Structure Characterization of Bacterial Microcompartment Shells via X-ray Scattering and Coordinate Modeling: Evidence for adventitious capture of cytoplasmic proteins
Zuo, X.; Jussupow, A.; Ponomarenko, N. S.; Tefft, N. M.; Yadav, N. S.; Range, K. L.; Ralston, C. Y.; TerAvest, M. A.; Sutter, M.; Kerfeld, C. A.; Vermaas, J. V.; Feig, M.; Tiede, D. M.
10.1101/2024.11.13.623460 — biophysics — Posted on 2024-11-15
2387 IMMClock reveals immune aging and T cell function at single-cell resolution
Schmidt, Y. G.; Wu, D.; Madan, S.; Sinha, S.; Sahni, S.; Gopalan, V.; Wang, B.; Dhruba, S. R.; Schaffer, A. A.; Weng, N.-p.; Restifo, N. P.; Wang, K.; Ruppin, E.
10.1101/2024.11.13.623449 — bioinformatics — Posted on 2024-11-15
2395 Volumetric imaging and computation to explore contractile function in zebrafish hearts
Saberigarakani, A.; Patel, R.; Almasian, M.; Zhang, X.; Brewer, J.; Hassan, S.; Chai, J.; Lee, J.; Fei, B.; Yuan, J.; Carroll, K.; Ding, Y.
10.1101/2024.11.14.623621 — bioengineering — Posted on 2024-11-15
2397 Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation
Sung, J. J.; Shaw, J. R.; Rezende, J. D.; Dharmaraj, S.; Cottingham, A. L.; Weldemariam, M. M.; Jones, J. W.; Kane, M. A.; Pearson, R. M.
10.1101/2024.11.13.623417 — bioengineering — Posted on 2024-11-15
2398 Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species
Zhu, M.; Ma, M.; Luo, L.; Li, F.; Zhang, J.; Pan, Y.; Yang, L.; Xiao, Y.; Wang, Z.; Xian, B.; Zheng, Y.; Li, H.; Yang, J.
10.1101/2024.11.14.623693 — biochemistry — Posted on 2024-11-15
2400 Benchmarking Peak Calling Methods for CUT&RUN
Nooranikhojasteh, A.; Tavallaee, G.; Orouji, E.
10.1101/2024.11.13.622880 — genomics — Posted on 2024-11-15
2402 Bitter taste genetics and oral health in Canadian Longitudinal Study on Aging
Shafizadeh, M.; Bhatia, V.; Ahmed, S.; Drogemoller, B.; Stavropoulou, C.; St. John, P.; Bhullar, R.; Chelikani, P.; Hitchon, C.
10.1101/2024.11.12.623243 — genetics — Posted on 2024-11-15
2403 Analysis of Categorical Data with Logistic Regression and the Cochran-Mantel-Haenszel Tests in Biological Experiments
Androwski, R. J.; Popovitchenko, T.; Smart, A. J.; Ogino, S.; Wang, G.; Rongo, C.; Driscoll, M.; Roy, J.
10.1101/2024.11.14.623695 — genetics — Posted on 2024-11-15
2404 Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci
Soenksen, J.; Chen, J.; Varshney, A.; Martin, S.; MAGIC, ; Parker, S. C. J.; Morris, A. P.; Asimit, J. L.; Barroso, I.
10.1101/2024.11.13.623384 — genetics — Posted on 2024-11-15
2407 Rate of de novo mutations in the three-spined stickleback
Zhang, C.; Reid, K.; Schierup, M. H.; Wang, H.; Candolin, U.; Merila, J.
10.1101/2024.11.13.623523 — evolutionary biology — Posted on 2024-11-15
2410 Biomarkers of recovery: characterizing trophic flow following ecological restoration
Spindel, N. B.; Galloway, A. W. E.; Schram, J. B.; McNeill, D. G.; Bellis, V. S. K.; Guujaaw, N.; Yakgujanaas, J.; Thompson, M.; Lee, L. C.; Okamoto, D. K.
10.1101/2024.11.14.623625 — ecology — Posted on 2024-11-15
2411 FROM FEAR TO FEAST: RATTLESNAKES NAVIGATE THE LANDSCAPE OF FEAR TO OPTIMIZE FORAGING
Da Cunha, O.; Dominguez, R. P.; Horne, L. M.; Mead, J. J.; Fournier, C.; Johnson, J. D.; Seymoure, B. M.
10.1101/2024.11.14.623629 — ecology — Posted on 2024-11-15
2414 Jagged1 is a Notch-independent mechanotransducer in endothelial cells
Suarez Rodriguez, F.; Virtanen, N.; Kiviluoto, E.; Driessen, R. C. H.; Zhao, F.; Bouten, C. V. C.; Stassen, O. M. J. A.; Sahlgren, C. M.
10.1101/2024.11.14.623558 — cell biology — Posted on 2024-11-15
2416 Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism
Lin, H.; Chen, D.; Zhang, F.; Liu, X.; Xie, X.; Dong, Q.; Yan, J.; Yin, J.; Bi, Z.; Jiang, K.; Zhang, T.; Xue, P.; Peng, W.; Chen, L.; Xu, T.; Guo, Y.; Li, Z.; Liu, H.
10.1101/2024.11.14.623532 — cell biology — Posted on 2024-11-15
2418 ATR safeguards replication forks against APOBEC3B-induced toxic PARP1 trapping
Ortega, P.; Bournique, E. B.; Li, J.; Sanchez, A.; Santiago, G.; Harris, B. R.; Green, A. M.; Buisson, R.
10.1101/2024.11.14.623607 — molecular biology — Posted on 2024-11-15
2420 Negative regulation of miRNAs sorting in EVs: the RNA-binding protein PCBP2 impairs SYNCRIP-mediated miRNAs EVs loading
Marocco, F.; Garbo, S.; Montaldo, C.; Colantoni, A.; Quattrocchi, L.; Gaboardi, G.; Cicchini, C.; Tartaglia, G. G.; Battistelli, C.; Tripodi, M.
10.1101/2024.11.15.623754 — molecular biology — Posted on 2024-11-15
2421 autoFISH - a modular toolbox for sequential smFISH experiments
Weber, C.; Defard, T.; Lelek, M.; Laporte, H.; Mallick, A.; Londono-Vallejo, J.-A.; Walter, T.; Fouillade, C.; Gariboldi, M. I.; Muller, F.
10.1101/2024.11.14.623566 — molecular biology — Posted on 2024-11-15
2422 Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical Screen
Azeroglu, B.; Khurana, S.; Wang, S.-C.; Tricola, G. M.; Sharma, S.; Jubelin, C.; Cortolezzis, Y.; Pegoraro, G.; Miller, K. M.; Stracker, T. H.; Lazzerini Denchi, E.
10.1101/2024.11.15.623791 — molecular biology — Posted on 2024-11-15
2424 Exploring the druggability of the UEV domain of human TSG101 in search for broad-spectrum antivirals
Montero, F.; Parra-Lopez, M.; Rodriguez-Martinez, A.; Murciano-Calles, J.; Buzon, P.; Han, Z.; Lin, L. Y.; Ramos, M. C.; Ruiz-Sanz, J.; Martinez, J. C.; Radi, M.; Moog, C.; Diederich, S.; Harty, R. N.; Perez-Sanchez, H.; Vicente, F.; Castillo, F.; Luque, I.
10.1101/2024.11.15.623737 — molecular biology — Posted on 2024-11-15
2427 Temperature modulates the dissemination potential of Microsporidia MB, a malaria-blocking endosymbiont of Anopheles mosquitoes
Otieno, F. G.; Barreaux, P.; Belvinos, A. S.; Makhulu, E. E.; Onchuru, T. O.; Wairimu, A. W.; Omboye, S. M.; King'ori, C. N.; Mawuko, S. B.; Kebira, A. N.; Herren, J. K.
10.1101/2024.11.15.623820 — microbiology — Posted on 2024-11-15
2428 Multi-layered ecological interactions determine growth of clinical antibiotic-resistant strains within human microbiomes
Leon-Sampedro, R.; Boumasmoud, M.; Reichlin, M.; Pfrunder-Cardozo, K. R.; Noll, N.; Egli, A.; Hall, A. R.
10.1101/2024.11.15.623752 — microbiology — Posted on 2024-11-15
2430 Unveiling novel conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling.
Bertrand, L.; Nelde, A.; Ramirez, B. C.; Hatin, I.; Arbes, H.; Francois, P.; Demais, S.; Labaronne, E.; Decimo, D.; Guiguettaz, L.; Gregoire, S.; Bet, A.; Beauclair, G.; Gross, A.; Ziegler, M.; Pereira, M.; Jeger-Madiot, R.; Verdier, Y.; Vinh, J.; Cardinaud, S.; Graff-Dubois, S.; Esclatine, A.; Gouttefangeas, C.; Altfeld, M.; HOCQUELOUX, L.; Samri, A.; Autran, B.; Lambotte, O.; Hans-Georg, R.; Ricci, E. P.; Walz, J.; NAMY, O.; Moris, A.
10.1101/2024.11.12.623167 — immunology — Posted on 2024-11-15
2431 Companion to: A molecular basis for milk allergen immune recognition in eosinophilic esophagitis
Dilollo, J.; Hu, A.; Qu, H.; Canziani, K. E.; Clement, R. L.; McCright, S. J.; Shreffler, W. G.; Hakonarson, H.; Spergel, J. M.; Cerosaletti, K.; Hill, D. A.
10.1101/2024.11.13.623408 — immunology — Posted on 2024-11-15
2434 A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins.
Kelpsch, D. J.; Zhang, L.; Thierer, J. H.; Koren, K.; Kumar, U.; Lin, Y.; Hensley, M. R.; Sohn, M.; Liu, J. O.; Lectka, T.; Mumm, J. S.; Farber, S. A.
10.1101/2024.11.14.623618 — physiology — Posted on 2024-11-15
2435 Hormone-induced thrombosis is mediated through non-canonical fibrin(ogen) aggregation and a novel estrogen target in zebrafish
Yu, X.; Zhao, Q. Y.; Yaman, M.; Emly, S. M.; Lee, J. K.; Su, H.; Ferguson, A. C.; Nagaswami, C.; Chaturantabut, S.; Goessling, W.; Weisel, J. W.; Auchus, R. J.; Shavit, J. A.
10.1101/2024.11.13.623199 — pathology — Posted on 2024-11-15
2437 Acute Myeloid Leukemia with deletion 5q is an epigenetically distinct subgroup defined by heterozygous loss of KDM3B
Kelly, K.; Welte, L.; Sollier, E.; Riedel, A.; Browne-Burke, F.; Scherer, M.; Keer, H. N.; Azab, M.; Jahn, E.; Doehner, H.; Doehner, K.; Lutsik, P.; Plass, C.
10.1101/2024.11.13.623380 — cancer biology — Posted on 2024-11-15
2438 Metabolic reprogramming and synergistic cytotoxicity of genistein and chemotherapy in human breast cancer cells
Tobon-Cornejo, S.; Vargas-Castillo, A.; Juarez, M.; Acevedo-Carabantes, J. A.; Noriega, L. G.; Granados-Portillo, O.; Chavez-Blanco, A.; Morales-Barcenas, R.; Torres, N.; Tovar, A. R.; Schcolnik-Cabrera, A.
10.1101/2024.11.13.623452 — cancer biology — Posted on 2024-11-15
2440 Structural insights into the opening mechanism of C1C2 channelrhodopsin
Mulder, M.; Hwang, S.; Broser, M.; Bruenle, S.; Skopintsev, P.; Schattenberg, C.; Schnick, C.; Hartmann, S.; Church, J.; Schapiro, I.; Dworkowski, F.; Weinert, T.; Hegemann, P.; Sun, H.; Standfuss, J.
10.1101/2024.11.14.623569 — biophysics — Posted on 2024-11-15
2443 Steric Repulsion Counteracts ER-to-Lipid Droplet Protein Movement
Damm, A.; Stojanovic, O.; Esch, B. M.; Carpentier, M.; Omrane, M.; Foret, L.; Froehlich, F.; Klemm, R. W.; THIAM, A. R.
10.1101/2024.11.14.623598 — biophysics — Posted on 2024-11-15
2444 Leveraging chromatin packing domains to target chemoevasion in vivo
Frederick, J.; Virk, R. K. A.; Ye, I. C.; Almassalha, L. M.; Wodarcyk, G. M.; VanDerway, D.; Carrillo Gonzalez, P.; Nap, R. J.; Agrawal, V.; Anthony, N. M.; Carinato, J.; Li, W. S.; Dunton, C. L.; Medina, K. I.; Kakkaramadam, R.; Jain, S.; Shahabi, S.; Ameer, G.; Szleifer, I. G.; Backman, V.
10.1101/2024.11.14.623612 — biophysics — Posted on 2024-11-15
2446 Auto-regulation of the real-time kinetics of the human mitochondrial replicative helicase
Plaza G-A, I.; Ortiz-Rodriguez, M.; Buchanan, S. P.; Miguez, S.; Lemishko, K.; Moreno-Herrero, F.; Fernandez-Leiro, R.; Ciesielski, G.; Ibarra, B.
10.1101/2024.11.14.623559 — biophysics — Posted on 2024-11-15
2447 Lipid Packing Defects are Necessary and Sufficient for Membrane Binding of alpha-Synuclein
Johnson, D. H.; Kou, O. H.; White, J. M.; Ramirez, S. Y.; Margaritakis, A.; Chung, P. J.; Jaeger, V. W.; Zeno, W. F.
10.1101/2024.11.14.623669 — biophysics — Posted on 2024-11-15
2450 A Multi-Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design
Liu, J.; Cui, T.; Wang, T.; Zeng, X.; Niu, Y.; Jiao, S.; Lu, D.; Wang, J.; Xiao, S.; Xie, D.; Wang, X.; Wang, Y.; Shang, X.; Wei, Z.; Peng, J.
10.1101/2024.11.13.623386 — bioinformatics — Posted on 2024-11-15
2454 Generating Biomedical Knowledge Graphs from Knowledge Bases, Registries, and Multiomic Data
Qin, G.; Narsinh, K.; Wei, Q.; Roach, J. C.; Joshi, A.; Goetz, S. L.; Moxon, S. T.; Brush, M. H.; Xu, C.; Yao, Y.; Glen, A. K.; Morris, E. D.; Ralevski, A.; Roper, R.; Belhu, B.; Zhang, Y.; Shmulevich, I.; Hadlock, J.; Glusman, G.
10.1101/2024.11.14.623648 — bioinformatics — Posted on 2024-11-15
2456 Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions
O'Hern, C.; Caywood, S.; Aminova, S.; Kiselev, A.; Volmert, B.; Wang, F.; Sewavi, M.-L.; Cao, W.; Dionise, M.; Muniyandi, P.; Popa, M.; Basrai, H.; Skoric, M.; Boulos, G.; Huang, A.; Nunez-Regueiro, I.; Chalfoun, N.; Park, S.; Zhou, C.; Contag, C. H.; Aguirre, A.
10.1101/2024.11.13.623051 — bioengineering — Posted on 2024-11-15
2457 Universal base editing for hemophilia B
Baatartsogt, N.; Kashiwakura, Y.; Hiramoto, T.; Ito, R.; Sato, R.; Nagao, Y.; Naruoka, H.; Takata, H.; Hayakawa, M.; Batjargal, K.; Togashi, T.; Hoshino, A.; Shimizu, T.; Sato, Y.; Ishida, T.; Nureki, O.; Ohmori, T.
10.1101/2024.11.13.623331 — bioengineering — Posted on 2024-11-15
2458 Optimization of the VSV G backbone for amino terminal fusion with nanobodies allowing its retargeting to receptors of therapeutic interest.
Duquenois, I.; Thebault, S.; Johari, S.; Raux, H.; Lagaudriere-Gesbert, C.; Perez, F.; Albertini, A. A.; Gaudin, Y.
10.1101/2024.11.14.623577 — bioengineering — Posted on 2024-11-15
2459 Common AAV gene therapy vectors show indiscriminate transduction of living human brain cell types
McGinnis, J.; Ortiz-Guzman, J.; Guevara, M. C.; Mallannagari, S.; Belfort, B. D.; Bao, S.; Srivastava, S.; Morkas, M.; Ji, E.; Addison, A.; Tantry, E.; Chen, S.; Wang, Y.; Chen, Z.; Katlowitz, K. A.; Lange, J. J.; Blessing, M.; Mohila, C.; Ljungberg, M. C.; Aldave, G.; Jalali, A.; Patel, A.; Sheth, S.; Weiner, H. L.; Gopinath, S.; Rao, G.; Serin-Harmanci, A.; Curry, D.; Arenkiel, B.
10.1101/2024.11.14.623624 — bioengineering — Posted on 2024-11-15
2463 Minus the Error: Estimating dN/dS and Testing for Natural Selection in the Presence of Residual Alignment Errors
Selberg, A.; Chikina, M.; Sackton, T. B.; Muse, S.; Lucaci, A.; Weaver, S.; Nekrutenko, A.; Clark, N.; Pond, S. L. K.
10.1101/2024.11.13.620707 — evolutionary biology — Posted on 2024-11-15
2464 Shading does not lower thermal tolerance in the coral Montipora capitata: implications for conservation intervention
Ducret, H.; Suchocki, C. R.; Bardin, C. E.; Lewis, C. J.; Permentier, T.; Hardt, M.; Toonen, R. J.; Kochzius, M.; Flot, J.-F.
10.1101/2024.11.13.623387 — ecology — Posted on 2024-11-15
2467 Integrating Nanopore MinION Sequencing into National Animal Health AMR Surveillance Programs: An Indonesian Pilot Study of Chicken Slaughterhouse Effluent and Rivers
Telussa, R.; Rahayu, P.; Yunindika, T.; Kapsak, C.; Rahayu, K. P.; Susanti, O.; Suandy, I.; Triwijayanti, N.; Niasono, A. B.; Ma'arif, S.; Wibawa, H.; Lestari, L.; Utomo, G. B.; Zenal, F. C.; Schoonman, L.; Gaeddert, L.
10.1101/2024.11.14.623636 — molecular biology — Posted on 2024-11-15
2468 Compositional changes of the lung extracellular matrix in acute respiratory distress syndrome
Fan, Y.; Moser, J.; Jongman, R.; Borghuis, T.; Vonk, J. M.; Timens, W.; van Meurs, M.; Pillay, J.; Burgess, J. K.
10.1101/2024.11.14.623462 — molecular biology — Posted on 2024-11-15
2469 Sla2 is a core interaction hub for Clathrin Light Chain and the Pan1/End3/Sla1Complex
Draper-Barr, G.; Defelipe, L.; Ruiz Carrillo, D.; Gustavsson, e.; Landau, M.; Garcia-Alai, M. M.
10.1101/2024.11.14.623549 — molecular biology — Posted on 2024-11-15
2470 Deciphering the function of Com_YlbF domain-containing proteins in Staphylococcus aureus.
Rozo, Z. L. C.; Ortiz, R. A. M.; Romero, M. L. V.; Riano, D. A.; Madronero, L. J.; Gomez, L. F. P.; Gomez, G. N. V.; Martinez, B. G.; Sarasua, M. E.; Pelaez, M. A. C.; Olaya, J. C.; Morales, L.; Clavijo, C. N.; Perez, J. A. E.
10.1101/2024.11.14.623514 — molecular biology — Posted on 2024-11-15
2473 International multi-cohort analysis identifies novel framework for quantifying immune dysregulation in critical illness: results of the SUBSPACE consortium
Moore, A. R.; Zheng, H.; Ganesan, A.; Hasin-Brumshtein, Y.; Maddali, M. V.; Levitt, J. E.; van der Poll, T.; Scicluna, B.; Giamarellos-Bourboulis, E. J.; Kotsaki, A.; Martin-Loeches, I.; Garduno, A.; Rothman, R. E.; Sevransky, J.; Wright, D. W.; Atreya, M. R.; Moldawer, L. L.; Efron, P. A.; Marcela, K.; Karvunidis, T.; Giannini, H. M.; Meyer, N. J.; Sweeney, T. E.; Rogers, A. J.; Khatri, P.
10.1101/2024.11.12.623298 — immunology — Posted on 2024-11-15
2474 Butyrophilin 2A2 promotes T cell immunoregulation by enhancing CD45 phosphatase activity within the immune synapse
Ali, S.; Berg, A. H.; Yamashita, M.; Covarrubias, A. E.; Zhang, R.; Dupont, V.; Shin, B.-H.; Yang, S.; Murali, R.; Katiki, M.; Pisarska, M. D.; Thadhani, R.; Heeger, P. S.; Jordan, S. C.; Karumanchi, S. A.
10.1101/2024.11.12.623303 — immunology — Posted on 2024-11-15
2475 Unbiased discovery of antibody therapies that stimulate macrophage-mediated destruction of B-cell lymphoma
Ribeiro, J.; Pages-Geli, C.; Meglan, A.; Velarde, J.; Blandin, J.; Vaccaro, K.; Wienclaw, T.; Fernandez-Guzman, P.; Hahn, C. K.; Crespo, M.; Weiskopf, K.
10.1101/2024.11.13.623229 — immunology — Posted on 2024-11-15
2477 Logic-based machine learning predicts how escitalopram inhibits cardiomyocyte hypertrophy
Eggertsen, T. G.; Travers, J. G.; Hardy, E. J.; Wolf, M. J.; McKinsey, T. A.; Saucerman, J. J.
10.1101/2024.11.13.623416 — systems biology — Posted on 2024-11-15
2478 Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer
Ireland, A. S.; Hawgood, S. B.; Xie, D. A.; Barbier, M. W.; Lucas-Randolph, S.; Tyson, D. R.; Zuo, L. Y.; Witt, B. L.; Govindan, R.; Dowlati, A.; Moser, J. C.; Puri, S.; Rudin, C. M.; Chan, J. M.; Elliott, A.; Oliver, T. G.
10.1101/2024.11.13.623500 — cancer biology — Posted on 2024-11-15
2482 Dynamically arrested condensate fusion creates complex structures with varying material properties
Erkamp, N. A.; Sanchez-Burgos, I. A.; Zhou, A.; Krug, T. J.; Qamar, S. S.; Sneideris, T.; Zhang, E.; Nakajima, K.; Chen, A.; Collepardo-Guevara, R.; Van Hest, J.; St George-Hyslop, P.; Weitz, D.; Rene Espinosa, J.; Knowles, T.
10.1101/2024.11.15.623768 — biophysics — Posted on 2024-11-15
2483 Ultrafast elastocapillary fans control agile maneuvering in ripple bugs and robots
Ortega-Jimenez, V.; Kim, D.; Kumar, S.; Kim, C.; Koh, J.-s.; Bhamla, M. S.
10.1101/2024.11.15.623609 — biophysics — Posted on 2024-11-15
2484 Organization of the Proteostasis Network of Membraneless Organelles
Lim, C. M.; Bian, Y.; Gonzalez-Diazag, A.; Pun, F.; Zhavoronkov, A.; Morimoto, R.; Vendruscolo, M.
10.1101/2024.11.12.623332 — bioinformatics — Posted on 2024-11-15
2485 scCompass: An integrated cross-species scRNA-seq database for AI-ready
Wang, P.; Liu, W.; Wang, J.; Liu, Y.; Li, P.; Xu, P.; Cui, W.; Zhang, R.; Long, Q.; Hu, Z.; Fang, C.; Dong, J.; Zhang, C.; Chen, Y.; Wang, C.; Liu, G.; Xie, H.; Zhang, Y.; Xiao, M.; Chen, S.; Chen, Y.; Yang, G.; Zhang, S.; Meng, Z.; Wang, X.; Feng, G.; Li, X.; Zhou, Y.
10.1101/2024.11.12.623138 — bioinformatics — Posted on 2024-11-15
2487 An Open Access Resource for Marmoset Neuroscientific Apparatus
Rollin, I. Z.; Papoti, D.; Bishop, M.; Szczupak, D.; Corigliano, M. R.; Hitchens, T. K.; Zhang, B.; Pell, S. K. A.; Guretse, S. S.; Dureux, A.; Murai, T.; Rizzo, S. J. S.; Klassen, L. M.; Zeman, P.; Gilbert, K. M.; Menon, R. S.; Lin, M.-K.; Everling, S.; Silva, A. C.; Schaeffer, D. J.
10.1101/2024.11.12.623252 — bioengineering — Posted on 2024-11-15
2488 In vitro FLASH irradiation of A549 lung cancer cells and IMR90 healthy human fibroblasts in the synchrocyclotron room of a clinical proton therapy system
Zazpe, A.; del Monte-Garcia, I.; Palao, N.; Cerron, F.; Cueto-Remacha, M.; Paula Linzoain-Agos, P.; Iniesta-Gonzalez, M.; Quartieri, M.; Cuesta, A. M.; Espana, S.; Velasco, G.; Vera-Sanchez, J. A.; Fraile, L. M.; Mazal, A.; Udias, J. M.; Porras, A.; Bragado, P.; Gutierrez-Uzquiza, A.; Sanchez-Parcerisa, D.
10.1101/2024.11.13.623375 — bioengineering — Posted on 2024-11-15
2491 Mosquito Wing Image Repository for Advancing Research on Geometric Morphometric- and AI-Based Identification
Nolte, K.; Agboli, E.; Azambuja Garcia, G.; Badolo, A.; Becker, N.; Do Huy, L.; Dworrak, T. V.; Eguchi, J.; Eisenbarth, A.; Maciel de Freitas, R.; Doumna-Ndalembouly, A. G.; Heitmann, A.; Jansen, S.; Joest, A.; Joest, H.; Kiel, E.; Meyer, A.; Pfitzner, W.-P.; Saathoff, J.; Schmidt-Chanasit, J.; Sulesco, T.; Tokatlian, A.; Velavan, T. P.; Villacanas de Castro, C.; Wehmeyer, M. L.; Zahouli, J.; Sauer, F. G.; Luehken, R.
10.1101/2024.11.13.623340 — ecology — Posted on 2024-11-15
2492 Going with the flow: leveraging reef-scale hydrodynamics for upscaling larval-based restoration
Gouezo, M.; Langlais, C.; Beardlsey, J.; Roff, G.; Harrison, P.; Thomson, D.; Doropoulos, C.
10.1101/2024.11.12.623286 — ecology — Posted on 2024-11-15
2496 A genome-wide ATLAS of liver chromatin architecture reveals that sex dictates diet-induced nucleosome dynamics
ZHANG, Z.; Su, V.; Wiese, C. B.; Cheng, L.; Wang, D.; Cui, Y.; Kim, J.; Wu, X.; Tran, P. H.; Zhou, Z.; Casero, D.; Li, W.; Hevener, A. L.; Reue, K.; Sallam, T.
10.1101/2024.11.13.623052 — molecular biology — Posted on 2024-11-15
2498 Alveolar macrophages initiate the spatially targeted neutrophil recruitment during nanoparticle inhalation
Liu, Q.; Yang, L.; Li, C.; Zhou, Q.; Han, L.; Schroeppel, A.; Kutschke, D.; Secklehner, J.; Yildirim, A. O.; Zeuschner, D.; Carlin, L. M.; Sperandio, M.; Schmid, O.; Stoeger, T.; Rehberg, M.
10.1101/2024.11.13.623349 — immunology — Posted on 2024-11-15
2499 High-resolution imaging atlas reveals context-dependent role of pancreatic sympathetic innervation in diabetic mice
Xu, Q.; Chen, Y.; Ni, X.; Zhuang, H.; Cao, S.; Zhao, L.; Wang, L.; Chen, J.; Yang, W.; Zeng, W.; Li, X.; Sun, H.; Shen, W.
10.1101/2024.11.14.623708 — neuroscience — Posted on 2024-11-15
2501 Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab resistant HER2 positive breast cancer
Hua, Y.; Duan, N.; Sun, C.; Yang, F.; Tian, M.; Sun, Y.; Zhao, S.; Gong, J.; Liu, Q.; Huang, X.; Liang, Y.; Fu, Z.; Li, W.; Yin, Y.
10.1101/2024.11.12.623302 — cancer biology — Posted on 2024-11-15
2502 The assessment of therapeutic autophagy inhibition in NF1 mutated tumor cells
Zahedi, S.; Mulcahy Levy, J.; Baird-Daniel, E.; Williams, K. B.; Williams, R. L.; Morin, A.; Crespo, M.; Bratbak, E.; Jones, K.; Vibhakar, R.; Foreman, N. K.; Largaespada, D. A.
10.1101/2024.11.12.623325 — cancer biology — Posted on 2024-11-15
2505 Multi-objective computational optimization of human 5' UTR sequences
Yamada, K.; Suga, K.; Abe, N.; Hashimoto, K.; Tsutsumi, S.; Inagaki, M.; Hashiya, F.; Abe, H.; Hamada, M.
10.1101/2024.11.12.622374 — bioinformatics — Posted on 2024-11-15
2507 Automated plasmid design for marker-free genome editing in budding yeast
Stojkovic, L.; Gligorovski, V.; Geramimanesh, M.; Labagnara, M.; Rahi, S. J.
10.1101/2024.11.12.623283 — bioinformatics — Posted on 2024-11-15
2509 GPU-accelerated homology search with MMseqs2
Kallenborn, F.; Chacon, A.; Hundt, C.; Sirelkhatim, H.; Didi, K.; Dallago, C.; Mirdita, M.; Schmidt, B.; Steinegger, M.
10.1101/2024.11.13.623350 — bioinformatics — Posted on 2024-11-15
2510 Proteostasis Associated Variants in HSPB5 Destabilize the αB-crystallin Domain
Khatun, M. S.; Ali, M. C.; Barua, L.; Munni, Y. A.; Dash, R.; Rahman, M. M.
10.1101/2024.11.12.623266 — bioinformatics — Posted on 2024-11-15
2511 Wound state monitoring by multiplexed, electrochemical, real-time, localized, inflammation-tracking nitric oxide sensor (MERLIN)
Wang, L.; Wang, Y.; Bartlett, M.; San Roman, D.; Balakrishnan, G.; Gershanok, S.; Khan, R.; Skillen, C.; Butler, S.; Kulkarni, M.; Cohen-Karni, D.; Brown, B.; Cohen-Karni, T.
10.1101/2024.11.12.623289 — bioengineering — Posted on 2024-11-15
2512 Multi-stage-mixing to create a core-then-shell structure improves DNA-loaded lipid nanoparticles transfection by orders of magnitude
Nong, J.; Gong, X.; Dang, Q. M.; Tiwari, S.; Patel, M.; Wu, J.; Hanna, A.; Park, W.-J.; Atochina-Vasserman, E. N.; Huang, H.-T.; Marcos-Contreras, O. A.; Morris-Blanco, K. C.; Miner, J. J.; Weissman, D.; Muzykantov, V. R.; Gupta, K.; Issadore, D.; Myerson, J. W.; Wang, Z.; Brenner, J. S.
10.1101/2024.11.12.623321 — bioengineering — Posted on 2024-11-15
2513 Volumetric and Diffusion Tensor Imaging biomarkers indicating long lasting post-concussion abnormalities in a youth pig model of mild Traumatic Brain Injury
Islam, S.; Netzley, A.; Chenyang, L.; Zhang, J.; Montero, B. D.; Vazquez, A.; Subbaiah, S.; Meoded, A.; Munoz, K.; Colbath, A.; Huang, J.; Mejia-Alvarez, R.; Manfredi, J.; Pelled, G.
10.1101/2024.11.12.623259 — bioengineering — Posted on 2024-11-15
2517 Integrating Machine Learning with Flow-Imaging Microscopy for Automated Monitoring of Algal Blooms
Khan, F.; Gincley, B.; Busch, A.; Tolofari, D. L.; Norton, J. W.; Varga, E.; McKay, R. M. L.; Fuentes-Cabrera, M.; Slawecki, T.; Pinto, A. J.
10.1101/2024.11.12.623192 — ecology — Posted on 2024-11-15
2518 Urban greenspace connectivity drive shifts in host assemblages and tick-borne pathogen infection
VanAcker, M. C.; Hofmeester, T. R.; Zhang-Sun, J.; Goethert, H. C.; Diuk-Wasser, M. A.
10.1101/2024.11.12.623035 — ecology — Posted on 2024-11-15
2521 Single-cell analyses reveal that monocyte gene expression profiles influence HIV-1 reservoir size in acutely treated cohorts
Ehrenberg, P. K.; Geretz, A.; Volcic, M.; Izumi, T.; Yum, L.; Waickman, A.; Shangguan, S.; Paquin-Proulx, D.; Creegan, M.; Bose, M.; Machmach, K.; McGraw, A.; Narahari, A.; Currier, J. R.; Sacdalan, C.; Phanuphak, N.; Apps, R.; Corley, M.; Ndhlovu, L. C.; Slike, B.; Krebs, S. J.; Anonworanich, J.; Tovanabutra, S.; Robb, M. L.; Eller, M. A.; Laird, G. M.; Cyktor, J.; Daar, E. S.; Crowell, T. A.; Mellors, J. W.; Vasan, S.; Michael, N. L.; Kirchhoff, F.; Thomas, R.
10.1101/2024.11.12.623270 — immunology — Posted on 2024-11-15
2522 Attentional failures after sleep deprivation represent moments of cerebrospinal fluid flow
Yang, Z.; Williams, S.; Beldzik, E.; Anakwe, S.; Schimmelpfennig, E.; Lewis, L. D.
10.1101/2024.11.15.623271 — neuroscience — Posted on 2024-11-15
2523 Variable Cerebral Blood Flow Responsiveness to Acute Hypoxic Hypoxia
Johnson, H. R.; Wang, M. C.; Stickland, R. C.; Chen, Y.; Parrish, T. B.; Sorond, F. A.; Bright, M. G.
10.1101/2024.11.14.623430 — neuroscience — Posted on 2024-11-15
2524 Single MAPT knock-in mouse models of frontotemporal dementia for sharing with the neurodegenerative research community
Morito, T.; Kamano, N.; Qi, M.; Watamura, N.; Endo, T.; Benner, S.; Higuchi, M.; Shimojo, M.; Sahara, N.; Mizuma, H.; Hama, H.; Kurokawa, H.; Miyawaki, A.; Duff, K.; Foiani, M.; Sado, T. C.; Sasaguri, H.; Bez, S.
10.1101/2024.11.15.623736 — neuroscience — Posted on 2024-11-15
2526 Filling-in of the Blindspot is Multisensory
Chan, A.; Stiles, N. R. B.; Levitan, C. A.; Tanguay, A. R.; Shimojo, S.
10.1101/2024.11.15.623713 — neuroscience — Posted on 2024-11-15
2527 Regenerative potential of human enteric glia in a preclinical model of acute brain injury
Colitti, N.; Rice, E.; Desmoulin, F.; Combeau, M.; Parny, M.; Robert, L.; Buscail, E.; Bournet, B.; Vergnolle, N.; Raymond-Letron, I.; Loubinoux, I.; Cirillo, C.
10.1101/2024.11.15.623633 — neuroscience — Posted on 2024-11-15
2528 On Levodopa interactions with brain disease proteins at the nanoscale
Bergaglio, T.; Kummer, N.; Bhattacharya, S.; Thompson, D.; Campioni, S.; Nirmalraj, P.
10.1101/2024.11.15.623204 — neuroscience — Posted on 2024-11-15
2530 Unveiling epigenetic regulatory elements associated with breast cancer development
Jardanowska-Kotuniak, M.; Draminski, M.; Wlasnowolski, M.; Łapinski, M.; Sengupta, K.; Agarwal, A.; Filip, A.; Ghosh, N.; Pancaldi, V.; Grynberg, M.; Saha, I.; Plewczynski, D.; Dabrowski, M. J.
10.1101/2024.11.12.623187 — cancer biology — Posted on 2024-11-15
2533 Bridging Genomic Gaps: The Pan-Grass Syntenic Gene Set in Grass Crop Evolution
Dias, H. M.; Sagawa, G. I. A.; Torres-Rodriguez, V.; Mural, R. V.; Schnable, J. C.; Van Sluys, M.-A.
10.1101/2024.11.12.623179 — genomics — Posted on 2024-11-15
2537 AIP56, an AB toxin secreted by Photobacterium damselae subsp. piscicida, has tropism for myeloid cells
Freitas, I. L.; Macedo, F.; Oliveira, L.; Oliveira, P.; do Vale, A.; dos Santos, N. M. S.
10.1101/2024.11.12.623249 — immunology — Posted on 2024-11-15
2538 ENTPD3-specific CAR Regulatory T cells for Local Immune Control in T1D
Pieper, T.; Riet, T.; Saetzler, V.; McGovern, J.; Delsing, L.; Atkinson, M.; Lodie, T.; Jermutus, L.; Noyan, F.; Hust, M.; Kusmartseva, I.; Hagedorn, M.; Lieber, M.; Henschel, P.; Glaser, V.; Geffers, R.; Polansky-Biskup, J.; Yang, M.; Eiz-Vesper, B.; Bonifacius, A.; Martinez Llordella, M.; Bergerhoff, K.; Henry, L.; Penston, D.; Gavriil, A.; Grothier, T.; Nikolopoulou, E.; Demertzis, N.; Koullourou, V.; Cox, P.; Zarrouki, B.; Sini, M.; Pfeiff, J.; Matthiesen, I.; Hardtke-Wolenski, M.; Jaeckel, E.
10.1101/2024.11.12.622951 — immunology — Posted on 2024-11-15
2539 Chronic inflammation drives epididymal tertiary lymphoid structure formation and autoimmune fertility disorders
Elizagaray, M. L.; Barrachina, F.; Avenatti, M. C.; Bastepe, I.; Chen, A.; Odriozola, A.; Ukairo, O.; Da Ros, V.; Ottino, K.; Subiran, N.; Battistone, M. A.
10.1101/2024.11.12.623224 — immunology — Posted on 2024-11-15
2540 T cell mediated impairment of epithelial integrity in Crohn's disease
Hamoudi, S.; Hammoudi, N.; Bonnereau, J.; Sonn, A.; Capelle, E.; Bezault, M.; Chardiny, V.; Bonnet, J.; Tran Minh, M.-L.; Gornet, J.-M.; Baudry, C.; Corte, H.; Maggiori, L.; Toubert, A.; Becht, E.; Allez, M.; Le Bourhis, L.
10.1101/2024.11.12.621219 — immunology — Posted on 2024-11-15
2541 Capacity building needed to reap the benefits of access to biodiversity collections
Groom, Q.; Meeus, S.; Barrios, S.; Childs, C.; Clubbe, C.; Corbett, E.; Francis, S.; Gray, A.; Harding, L.; Jackman, A.; Machin, R.; McGovern, A.; Pienkowski, M.; Ryan, D.; Sealys, C.; Wensink, C.; Peyton, J.
10.1101/2024.11.12.623213 — scientific communication and education — Posted on 2024-11-15
2542 Vertical sleeve gastrectomy in rodents: impact on metabolic, cardiovascular and hepatic functions of mothers and perinatal consequences
Payen, C.; Guillot, A.; Chaigneau, J.; Bichot, L.; Testa, E.; Bourreau, J.; Gascoin, G.; Vessieres, E.; Proux, C.; Moal, V.; Loufrani, L.; Schmitt, F.; Fassot, C.
10.1101/2024.11.12.623181 — physiology — Posted on 2024-11-15
2543 The circadian gene Dec2 promotes pancreatic cancer dormancy by regulating tumor cell antigen presentation to facilitate immune evasion
Harris, C. R.; Wang, L.; Dudgeon, C.; Prela, O.; Cazarin de Menezes, J.; Shih, C.-H.; Davidson, C.; Casabianca, A.; De, S.; Narrow, W.; Becker, J.; Balachandran, V.; Grandgenett, P.; Grem, J.; Hollingsworth, M. A.; Kim, M.; Hong, Y.; Gerber, S. A.; Vertino, P. M.; Gao, C.; Repesh, A.; Klamer, Z.; Hao, Y.; Altman, B. J.; Haab, B. B.; Carpizo, D. R.
10.1101/2024.11.12.623005 — cancer biology — Posted on 2024-11-15
2550 iModMix: Integrative Module Analysis for Multi-omics Data
Narvaez-Bandera, I. Y.; Lui, A.; Mekonnen, Y. A.; Rubio, V.; Sulman, N.; Wilson, C. M.; Ackerman, H.; Ospina, O.; Gonzalez-Calderon, G.; Flores, E.; Li, Q.; Chen, Y. A.; Fridley, B.; Stewart, P. A.
10.1101/2024.11.12.623208 — bioinformatics — Posted on 2024-11-15
2551 AI-assisted imaging screening reveals mechano-molecular tissue organizers and network of signaling hubs.
Bertocchi, C.; Alegria, J. J.; Vasquez-Sepulveda, S.; Ibanez-Prat, R.; Srinivasan, A.; Arrano-Valenzuela, I.; Castro-Pereira, B.; Soto-Montandon, C.; Trujillo-Espergel, A.; Owen, G. I.; Kanchanawong, P.; Cerda, M.; Motta, G.; Zaidel-Bar, R.; Ravasio, A.
10.1101/2024.11.14.623670 — cell biology — Posted on 2024-11-15
2554 Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation
van der Heijden, E. S.; Nasvall, K.; Seixas, F. A.; Beserra Nobre, C. E.; Campos D Maia, A.; Salazar-Carrion, P. A.; Walker, J. M.; Szczerbowski, D.; Schulz, S.; Warren, I. A.; Gavilanes Cordova, K. G.; Sanchez-Carvajal, M. J.; Chandi, F.; Arias-Cruz, A. P.; Rueda-Munoz, N.; Salazar, C.; Dasmahapatra, K. K.; Montgomery, S. H.; McClure, M.; Absolon, D. E.; Mathers, T. C.; Santos, C. A.; McCarthy, S.; Wood, J.; Lamas, G.; Bacquet, C.; Freitas, A. V.; Willmott, K. R.; Jiggins, C. D.; Elias, M.; Meier, J. I.
10.1101/2024.07.07.602206 — evolutionary biology — Posted on 2024-11-15
2556 Interspecies Organoids Reveal Human-Specific Molecular Features of Dopaminergic Neuron Development and Vulnerability
Nolbrant, S.; Wallace, J. L.; Ding, J.; Zhu, T.; Sevetson, J. L.; Kajtez, J.; Baldacci, I. A.; Corrigan, E. K.; Hoglin, K.; McMullen, R.; Schmitz, M. T.; Breevoort, A.; Swope, D.; Wu, F.; Pavlovic, B. J.; Salama, S. R.; Kirkeby, A.; Huang, H.; Schaefer, N. K.; Pollen, A. A.
10.1101/2024.11.14.623592 — evolutionary biology — Posted on 2024-11-15
2557 A shift between r and K strategies in the life cycle of a unicellular microalga
Liu, L.; Tang, S.; Liu, Y.; Zhang, B.; Zhong, Y.; Liu, D.; Zhou, J.; Cai, Z.
10.1101/2024.09.24.614695 — ecology — Posted on 2024-11-15
2560 A Novel C. elegans Model for Tau spreading Reveals Genes Critical for Endolysosomal Integrity and Seeded Tau Aggregation
Sandhof, C. A.; Martin, N.; Tittelmeier, J.; Schlueter, A.; Pezzali, M.; Schoendorf, D. C.; Lange, T.; Reinhardt, P.; Ried, J. S.; Liang, S.; Uzunoglu, G.; Gasparini, L.; Jahn, T.; Ehrnhoefer, D. E.; Nussbaum-Krammer, C.
10.1101/2024.11.13.619586 — cell biology — Posted on 2024-11-15
2561 Insects evolved a monomeric histone-fold domain in the CENP-T protein family
Sankaranarayanan, S. R.; Ulmer, J.; Morch, A.; Ali-Ahmad, A.; Sekulic, N.; Drinnenberg, I. A.
10.1101/2024.11.15.623767 — cell biology — Posted on 2024-11-15
2563 Limited microglial metabolic improvement with time-restricted feeding in diet-induced obesity
Jiao, H.; Jermei, J.; Liang, X.; van der Zande, H. J. P.; Vrieling, F.; Rumanova, V. S.; Dorscheidt, M.; Correa-da-Silva, F.; Wang, A.; Foppen, E.; Arias, A. P.; Stenvers, D. J.; Liu, T.; Bonger, K.; Stienstra, R.; Zhi, Z.; Kalsbeek, A.; Yi, C.-X.
10.1101/2024.09.04.611250 — immunology — Posted on 2024-11-15
2564 A low-activity cortical network selectively encodes syntax
Morgan, A. M.; Devinsky, O.; Doyle, W.; Dugan, P.; Friedman, D.; Flinker, A.
10.1101/2024.06.20.599931 — neuroscience — Posted on 2024-11-15
2571 Analysis-ready VCF at Biobank scale using Zarr
Czech, E. A.; Millar, T. R.; Tyler, W.; White, T. E.; Jeffery, B.; Miles, A.; Tallman, S.; Wojdyla, R.; Zabad, S.; Hammerbacher, J.; Kelleher, J.
10.1101/2024.06.11.598241 — bioinformatics — Posted on 2024-11-15
2572 AllTheBacteria - all bacterial genomes assembled, available and searchable
Hunt, M.; Lima, L.; Anderson, D.; Hawkey, J.; Shen, W.; Lees, J.; Iqbal, Z.
10.1101/2024.03.08.584059 — bioinformatics — Posted on 2024-11-15
2573 Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin
Wada, K.; Kobayashi, K.; Era, I.; Isobe, Y.; Kamimura, T.; Marukawa, M.; Nagae, T.; Honjo, K.; Kaseda, N.; Motoyama, Y.; Inoue, K.; Sugishima, M.; Kusaka, K.; Yano, N.; Fukuyama, K.; Mishima, M.; Kitagawa, Y.; Unno, M.
10.1101/2024.09.12.612615 — biochemistry — Posted on 2024-11-15
2574 Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels
Hooda, Y.; Sente, A.; Judy, R. M.; Smalinskaite, L.; Peak-Chew, S.-Y.; Naydenova, K.; Malinauskas, T.; Hardwick, S. W.; Chirgadze, D. Y.; Aricescu, A. R.; Hegde, R. S.
10.1101/2024.10.28.620708 — biochemistry — Posted on 2024-11-15
2575 The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle
Günther, T.; Chisausky, J.; Galindo-Pellicena, M. A.; Iriarte, E.; Cortes Gardyn, O.; Eusebi, P. G.; Garcia-Gonzalez, R.; Urena, I.; Moreno, M.; Alday, A.; Rojo, M.; Perez, A.; Tejedor Rodriguez, C.; Garcia Martinez de Lagran, I.; Arsuaga, J. L.; Carretero, J.-M.; Götherström, A.; Smith, C.; Valdiosera, C.
10.1101/2023.07.19.548914 — genomics — Posted on 2024-11-15
2578 Harmonising distributed tree inventory datasets across India can fill critical gaps in tropical ecology
Anujan, K.; Mohanbabu, N.; Gopal, A.; Surendra, A.; Krishnan, A.; Jayanth, A.; Nair, T.; Ongole, S.; Sankaran, M.
10.1101/2024.05.18.594774 — ecology — Posted on 2024-11-15
2579 Camera traps unable to determine whether plasticine models of caterpillars reliably measure bird predation
SCHILLE, L.; PLAT, N.; BARBARO, L.; JACTEL, H.; RASPAIL, F.; RIVOAL, J.-B.; CASTAGNEYROL, B.; MRAZOVA, A.
10.1101/2024.10.01.616075 — ecology — Posted on 2024-11-15
2583 Smc5/6 association with microtubules controls dynamic pericentromeric chromatin folding
Carre-Simon, A.; Batrin, R.; Isler, S.; Dahl Pinholt, H.; Foldes, T.; Laflamme, G.; Barbi, M.; Mirny, L.; D'Amours, D.; Fabre, E.
10.1101/2024.11.13.623393 — cell biology — Posted on 2024-11-15
2585 Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids
Cao, X.; Wu, X.; Zhao, L.; Zheng, J.; Jin, X.; Hao, X.; Winderickx, J.; Liu, S.; Chen, L.; Liu, B.
10.1101/2023.09.27.559647 — cell biology — Posted on 2024-11-15
2586 Lipid Droplet Targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis
Teskey, G.; Tiwari, N.; Butcko, A. J.; Kumar, A.; Yadav, A.; Huang, Y.-m. M.; Kelly, C. V.; Granneman, J. G. G.; Perfield, J. W.; Mottillo, E. P.
10.1101/2024.10.03.616525 — cell biology — Posted on 2024-11-15
2587 Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance
Agostini, L.; Pfister, J.; Basnet, N.; Ding, J.; Zhang, R.; Biertumpfel, C.; O'Connell, K.; Mizuno, N.
10.1101/2024.11.13.623454 — cell biology — Posted on 2024-11-15
2593 Optochemical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites
Sicard, A.; Tian, M.; Mostefai, Z.; Shi, S.; Cardoso, C.; Zamith, J.; McCort-Tranchepain, I.; Charrier, C.; Paoletti, P.; Mony, L.
10.1101/2024.10.14.618157 — neuroscience — Posted on 2024-11-15
2594 Lipid polymorphism of the marginal region of plant thylakoid membranes
Böde, K.; Dlouhy, O.; Javornik, U.; Domonkos, I.; Zsiros, O.; Plavec, J.; Spunda, V.; Garab, G.
10.1101/2024.11.12.623231 — plant biology — Posted on 2024-11-15
2595 Data-guided direct reprogramming of human fibroblasts into the hematopoietic lineage
Stansbury, C.; Cwycyshyn, J.; Pickard, J.; Meixner, W.; Rajapakse, I.; Muir, L. A.
10.1101/2024.08.26.609589 — bioinformatics — Posted on 2024-11-15
2596 Molecular glues that inhibit deubiquitylase activity and inflammatory signalling
Chandler, F.; Reddy, P. A. N.; Bhutda, S.; Ross, R. L.; Datta, A.; Walden, M.; Walker, K.; Di Donato, S.; Cassel, J. A.; Prakesch, M. A.; Aman, A.; Datti, A.; Campbell, L. J.; Foglizzo, M.; Bell, L.; Stein, D. N.; Ault, J. R.; Al-awar, R. S.; Calabrese, A. N.; Sicheri, F.; Del Galdo, F.; Salvino, J. M.; Greenberg, R. A.; Zeqiraj, E.
10.1101/2024.09.07.611787 — biochemistry — Posted on 2024-11-15
2601 Computational analysis of morphological changes in Lactiplantibacillus plantarum under acidic stress
Venugopal, A.; Steinberg, D.; Moyal, O.; Yonnasi, S.; Glaicher, N.; Gitelman, E.; Shemesh, M.; Amitay, M.
10.1101/2024.11.14.623583 — systems biology — Posted on 2024-11-15
2602 Decrypting the complex phenotyping traits of plants by machine learning
Zdrazil, J.; Kong, L.; Klimes, P.; Jasso-Robles, F. I.; Saiz-Fernandez, I.; Guder, F.; Spichal, L.; Snasel, V.; De Diego, N.
10.1101/2024.11.14.623623 — plant biology — Posted on 2024-11-15
2603 Early seedling development in dark conditions is directly controlled by plastids through the GUN1-dependent plastid retrograde pathway
Sajib, S. A.; Bykowski, M.; Barreto, P.; Mauve, C.; Delannoy, E.; Blanchet, S.; Chamas, R.; Schwarzlander, M.; Kowalewska, L.; Gakiere, B.; Merendino, L.
10.1101/2024.11.13.623400 — plant biology — Posted on 2024-11-15
2606 LATE MERISTEM IDENTITY2 regulates cuticle formation on the seed surface and influences seed longevity
Oshima, Y.; Narumi, T.; Kaneko, Y.; Ishikawa, T.; Kawai-Yamada, M.; Ohme-Takagi, M.; Mitsuda, N.
10.1101/2024.11.14.623493 — plant biology — Posted on 2024-11-15
2607 Effect of endogenous earthworm's extracts on "plant growth-promoting fungi"
Yakkou, L.; Houida, S.; Raouane, M.; Hatipoglu, M.; Amghar, S.; El Harti, A.; Jaber, M. O. H.
10.1101/2024.11.14.623545 — plant biology — Posted on 2024-11-15
2609 Oligogalacturonides, produced by enzymatic degradation of sugar beet by-products, confer partial protection against wheat powdery mildew
Carton, C.; Safran, J.; Mohanaraj, S.; Roulard, R.; Domon, J.-M.; Bassard, S.; Facon, N.; Tisserant, B.; Mongelard, G.; Gutierrez, L.; Randoux, B.; Magnin-Robert, M.; Pelloux, J.; Pau-Roblot, C.; Lounes-Hadj Sahraoui, A.
10.1101/2024.11.15.623731 — plant biology — Posted on 2024-11-15
2611 The Arabidopsis Class I formin AtFH5 contributes to seedling resistance to salt stress.
Kollarova, E.; Forero, A. B.; Yildiz, A. B.; Kocova, H.; Zarsky, V.; Cvrckova, F.
10.1101/2024.11.13.623423 — plant biology — Posted on 2024-11-15
2613 Pith cell responses to low red: far-red light in dicot stems
Li, L.; van de Kaa, Y. T. R.; van der Krabben, L.; Pierik, R.; Kajala, K.
10.1101/2024.11.12.623171 — plant biology — Posted on 2024-11-15
2618 The association of Mediterranean plant species with herbivorous arthropods and its effect on pest abundance in organic vineyards
Santos, R.; Naves, P.; Morais, R.; Rodrigues, L. R.; Pina, S.; Santos, M.; Rebelo, M. T.; Garcia Pereira, P.; Magalhaes, S.; Figueiredo, E.
10.1101/2024.11.12.623178 — ecology — Posted on 2024-11-15
2619 Seed dispersal effectiveness and plant-bird interaction networks in the Tehuacan Valley
Contreras-Gonzalez, A. M.; Gonzalez-Montes, M. B.; Ortega-Jiminez, E. J.; Herrera-Serrano, P.; Rivera-Ortiz, F. A.; Valiente-Banuet, A.
10.1101/2024.11.12.623176 — ecology — Posted on 2024-11-15
2620 From naïve pluripotency to human neural organoids through a three-dimensional morphogenetic continuum
Laterza, C.; Cesare, E.; Stuart, H. T.; D'Ercole, M.; Gesualdo, A.; La Barbera, M. G.; Brignani, S.; Ribecco, C.; Polli, R.; Frison, R.; Angiolillo, S.; Maseta, A.; Gagliano, O.; Cacchiarelli, D.; Briscoe, J.; Tanaka, E. M.; Murgia, A.; Elvassore, N.
10.1101/2024.11.14.623407 — cell biology — Posted on 2024-11-15
2623 Leaf size determines damage- and herbivore-induced volatile emissions in maize
Waterman, J. M.; Cofer, T. M.; von Laue, O. M.; Mateo, P.; Wang, L.; Erb, M.
10.1101/2024.11.14.623649 — plant biology — Posted on 2024-11-15
2624 Targeted degradation of endogenous condensation-prone proteins improves crop performance
Xu, G.; Luo, M.; Wen, Q.; Zhu, S.; Dang, H.; Niu, R.; Long, J.; Wang, Z.; Tong, Y.; Ning, Y.; Yuan, M.
10.1101/2024.11.13.623495 — plant biology — Posted on 2024-11-15
2627 ABA increases fatty acids levels in apple roots to boost colonization by arbuscular mycorrhizal fungi
Jing, S.; Li, M.; Zhu, L.; Li, C.; Li, C. Y.; Du, L.; Wei, X.; Zhang, R. M.; Ma, B.; Ruan, Y.-L.; Ma, F.
10.1101/2024.11.13.623435 — molecular biology — Posted on 2024-11-15
2628 Hierarchical glycolytic pathways control the carbohydrate utilization regulator in human gut Bacteroides
Kabonick, S. G.; Verma, K.; Modesto, J. L.; Pearce, V. H.; Winokur, K. M.; Groisman, E. A.; Townsend, G. E.
10.1101/2024.11.13.623061 — microbiology — Posted on 2024-11-15
2632 MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants
Han, S.; Sun, X.; Sloofman, L.; Satterstrom, F. K.; Wang, G.; Liang, L.; Knoblauch, N.; Zhao, S.; Liu, Y.; Sheng, W.; Nguyen, H. T.; He, X.
10.1101/828061 — genetics — Posted on 2024-11-15
2633 WITHDRAWN: MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants
Han, S.; Sun, X.; Sloofman, L.; Satterstrom, F. K.; Wang, G.; Liang, L.; Knoblauch, N.; Zhao, S.; Liu, Y.; Shen, W.; Nguyen, H. T.; He, X.
10.1101/2024.10.24.620131 — genetics — Posted on 2024-11-15
2635 Vincristine treatment reverses podocyte damage in focal segmental glomerulosclerosis
Mason, W. J.; Chandler, J. C.; Pomeranz, G.; Price, K. L.; Antonelou, M.; Henderson, S. R.; Perin, L.; Da Sacco, S.; Salama, A. D.; Long, D. A.; Pepper, R. J.
10.1101/2024.11.13.623397 — cell biology — Posted on 2024-11-15
2636 Anemia and tissue hypoxia are major determinants of malarial hypelactatemia
Georgiadou, A.; Yoon, C. E.; Yu, H.; Pearson, W. H.; Ueno, A.; Ebmeier, S.; Larrouy-Maumus, G.; Cunnington, A. J.
10.1101/2024.10.22.619641 — pathology — Posted on 2024-11-15
2638 Assessing Extracellular Vesicle Turnover In vivo Using Highly Sensitive Phosphatidylserine-Binding Reagents
Flaskamp, L.; Prechtl, M.; Scheck, A.; Hu, W.; Ried, C.; Kislinger, G.; Simons, M.; Krug, A.; Kranich, J.; Brocker, T.
10.1101/2024.11.14.623541 — cell biology — Posted on 2024-11-14
2640 A multi-tissue developmental gene expression atlas towards understanding the biological basis of phenotypes in sheep
Zhao, B.; Luo, H.; Fu, X.; Zhang, G.; Clark, E. L.; Wang, F.; Dalrymple, B. P.; Oddy, V. H.; Vercoe, P. E.; Wu, C.; Liu, G. E.; Li, C.-j.; Xiang, R.; Tian, K.; Zhang, Y.; Fang, L.
10.1101/2024.11.14.623505 — genetics — Posted on 2024-11-14
2641 Evolutionary consequences of domestication on the selective effects of new amino acid changing mutations in canids
G. Amorim, C. E.; Di, C.; Lin, M.; Marsden, C.; Del Carpio, C. A.; Mah, J. C.; Robinson, J. A.; Kim, B. Y.; Mooney, J. A.; Cornejo, O. E.; Lohmueller, K. E.
10.1101/2024.11.13.623529 — genetics — Posted on 2024-11-14
2642 Conservation of cis-regulatory codes over half a billion years of evolution
Ogawa, Y.; Liu, Y.; Myers, C. A.; Morshedian, A.; Fain, G. L.; Sampath, A. P.; Corbo, J. C.
10.1101/2024.11.13.623372 — evolutionary biology — Posted on 2024-11-14
2644 Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms
Hijazi, H.; Manessier, J.; Brugiere, S.; Ravnsborg, T.; Courcon, M.; Brule, B.; Merienne, K.; Jensen, O. N.; Hesse, A.-M.; Bruley, C.; Pflieger, D.
10.1101/2024.11.13.623238 — biochemistry — Posted on 2024-11-14
2648 Stimulus uncertainty and relative reward rates determine adaptive responding in perceptual decision-making
de la Cuesta-Ferrer, L.; Koss, C.; Starosta, S.; Kasties, N.; Lengersdorf, D.; Jäkel, F.; Stüttgen, M. C.
10.1101/2024.11.14.623587 — animal behavior and cognition — Posted on 2024-11-14
2649 Predictability of next elements in chimpanzee gesture sequences
Mielke, A.; Badihi, G.; Donnellan, E.; Graham, K. E.; Hashimoto, C.; Mine, J. G.; Piel, A. K.; Safryghin, A.; Slocombe, K. E.; Soldati, A.; Stewart, F. A.; Townsend, S. W.; Wilke, C.; Zuberbuhler, K.; Zulberti, C.; Hobaiter, C.
10.1101/2024.11.13.623362 — animal behavior and cognition — Posted on 2024-11-14
2651 Koolen-de Vries Syndrome causal gene KANSL1 is required for motile ciliogenesis
Schmidt, J. D.; Terala, A.; McCluskey, K. E.; Wang, B.; Pfalzer, A. C.; Willsey, H.
10.1101/2024.11.14.621349 — developmental biology — Posted on 2024-11-14
2652 Sox9 and Nfi transcription factors regulate the timing of neurogenesis and ependymal maturation in dopamine progenitors
Lahti, L.; Volakakis, N.; Gillberg, L.; Salmani, B. Y.; Tiklova, K.; Kee, N.; Lunden-Miguel, H.; Piper, M.; Gronostajski, R.; Perlmann, T.
10.1101/2024.11.12.623209 — developmental biology — Posted on 2024-11-14
2654 Novel function of Hox13 in regulating outgrowth of the newt hindlimb bud through interaction with Fgf10 and Tbx4
Tozawa, S.; Matsubara, H.; Minamitani, F.; Kamei, Y.; Saida, M.; Asao, M.; Suzuki, K.-i. T.; Matsunami, M.; Shigenobu, S.; Hayashi, T.; Abe, G.; Takeuchi, T.
10.1101/2024.11.12.623306 — developmental biology — Posted on 2024-11-14
2656 Efficient globin production during terminal erythropoiesis depends on the synergistic action of TENT5C poly(A) polymerase and LARP4/5
Mazur, M.; Guminska, N.; Brouze, A.; Cysewski, D.; Mleczko-Sanecka, K.; Niklewicz, M.; Kusio-Kobiałka, M.; Dziembowski, A.
10.1101/2024.11.14.623596 — developmental biology — Posted on 2024-11-14
2657 Calcium signalling is required for anterior patterning in the mouse embryo
Stower, M.; Tyser, R. C. V.; Thowfeequ, S.; Zhou, F. Y.; Portela, M.; Miti, K.; Sugnaseelan, J.; Lu, X.; Srinivas, S.
10.1101/2024.11.14.623160 — developmental biology — Posted on 2024-11-14
2659 Feature similarity: a sensitive method to capture the functional interaction of brain regions and networks to support flexible behavior
Wang, X.; Lyu, B.; Krieger-Redwood, K.; Souter, N. E.; Shafiei, G.; Lin, N.; Smallwood, J.; Jefferies, E.; Du, Y.
10.1101/2024.11.13.623324 — neuroscience — Posted on 2024-11-14
2668 Bidirectional Impact of miR-29a modulation on Memory Stability in the Adult Brain
Viglione, A.; Giannuzzi, C.; Putignano, E.; Mazziotti, R.; Cellerino, A. M.; Pizzorusso, T.
10.1101/2024.11.12.623333 — neuroscience — Posted on 2024-11-14
2670 Spatial Transcriptomic Analysis Identifies a SERPINA3-Expressing Astrocytic State Associated with the Human Neuritic Plaque Microenvironment
Karaahmet, B.; Zhang, Y.; Duquesne, L.; Sigalov, A.; Yung, C.; Kroshilina, A.; Bennett, D. A.; Taga, M.; Klein, H.-U.
10.1101/2024.11.13.623438 — neuroscience — Posted on 2024-11-14
2671 Modeling of blood flow dynamics in the rat somatosensory cortex
Battini, S.; Cantarutti, N.; Kotsalos, C.; Roussel, Y.; Cattabiani, A.; Arnaudon, A.; Favreau, C.; Antonel, S.; Markram, H.; Keller, D.
10.1101/2024.11.14.623572 — neuroscience — Posted on 2024-11-14
2673 Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild Traumatic Brain Injury
Munoz-Ballester, C.; Leitzel, O. J.; Golf, S. R.; Phillips, C. M.; Zeitz, M. J.; Smyth, J. W.; Lamouille, S.; Robel, S.
10.1101/2024.11.12.623104 — neuroscience — Posted on 2024-11-14
2674 Dynamic prioritisation of sensory and motor contents in working memory
Echeverria-Altuna, I.; Boettcher, S. E. P.; van Ede, F.; Nobre, A. C.
10.1101/2024.11.12.623203 — neuroscience — Posted on 2024-11-14
2675 Pathological microcircuits initiate epileptiform events in patient hippocampal slices
Elliott, M.; Andrews, J. P.; Molen, T. v. d.; Geng, J.; Spaeth, A.; Voitiuk, K.; Core, C.; Gillespie, T.; Sinervo, A.; Parks, D. F.; Robbins, A.; Solis, D.; Chang, E. F.; Nowakowski, T. J.; Teodorescu, M.; Haussler, D.; Sharf, T.
10.1101/2024.11.13.623525 — neuroscience — Posted on 2024-11-14
2676 No Effect of Value on the Task Irrelevant Auditory Mismatch Negativity
Hutchinson, B. T.; Jack, B. N. N.; Budd, A.; Calabro, R.; Fogarty, D.; Nicholls, M. E. R.; Griffiths, O.
10.1101/2024.11.12.623328 — neuroscience — Posted on 2024-11-14
2677 Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation
Kawanabe-Kobayashi, R.; Uchiyama, S.; Yoshihara, K.; Kojima, D.; McHugh, T. J.; Hatada, I.; Matsui, K.; Tanaka, K. F.; Tsuda, M.
10.1101/2024.11.14.623627 — neuroscience — Posted on 2024-11-14
2680 Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord
Tuddenham, J.; Fujita, M.; Khairallah, A.; Harbison, C.; Flowers, X. E.; Maniatis, S.; Daly, A.; Schneider, J. A.; Teich, A.; Vonsattel, J. P. G.; Sims, P. A.; Elyaman, W.; Bradshaw, E.; Hemali Phatnani, H.; Shneider, N.; Bennett, D. A.; De Jager, P.; Przedborski, S.; Menon, V.; Olah, M.
10.1101/2024.11.12.623183 — neuroscience — Posted on 2024-11-14
2685 Fructose-2,6-bisphosphate restores TDP-43 pathology-driven genome repair deficiency in motor neuron diseases
Mitra, J.; Chakraborty, A.; Malojirao, V. H.; Kodavati, M.; Mandal, S. M.; Vasquez, V.; Mankevich, M.; Ghosh, G.; Hegde, M.; Hazra, T.
10.1101/2024.11.13.623464 — neuroscience — Posted on 2024-11-14
2686 Calcium-based input timing learning
Kamalabad, S. S.; Schmitt, S.; Tetzlaff, C.
10.1101/2024.11.14.623617 — neuroscience — Posted on 2024-11-14
2687 Subcortical nuclei of the human ascending arousal system encode anticipated reward but do not predict subsequent memory
Lloyd, B.; Miletic, S.; Bazin, P.-L.; Isherwood, S.; Tse, D. H. Y.; Haberg, A.; Forstmann, B.; Nieuwenhuis, S.
10.1101/2024.11.12.623212 — neuroscience — Posted on 2024-11-14
2688 An integrative layer-resolved atlas of the adult human meninges
Degenhard, T.; Groh, A. M.; Afanasiev, E.; Luo, M.; Yaqubi, M.; Stratton, J. A.; Petrecca, K.
10.1101/2024.11.13.623440 — neuroscience — Posted on 2024-11-14
2689 A vector calculus for neural computation in the cerebellum
Fakharian, M. A.; Shoup, A.; Hage, P.; Elseweifi, H.; Shadmehr, R.
10.1101/2024.11.14.623565 — neuroscience — Posted on 2024-11-14
2692 Midbrain dopamine D2R regulates the salience of threat-related events
Castell, L.; Rogliardo, A.; Le Borgne, T.; Naon, C.; Cathala, A.; Puighermanal, E.; Makrini, L.; Mashhour, N.; Petit, C. P.; Bernat, C.; Nouvian, R. M.; Cutando, L.; Revest, J.-M.; Faure, P.; Besnard, A.; Bellone, C.; Monteil, A.; Gangarossa, G.; Marti, F.; Valjent, E.
10.1101/2024.11.12.623233 — neuroscience — Posted on 2024-11-14
2693 Mesenchymal Cell-Derived Extracellular Vesicles Ameliorate Age-Related Deficits in Working Memory as well as Brain MRI and CSF in vivo Biomarkers of Neurodegeneration in Rhesus Monkeys.
Mackie, E. C.; Cheng, C.-H.; Alibrio, M.; Rutledge, C.; Xin, H.; Chopp, M.; McCann, R.; Rosene, D. L.; Yang, Q.; Zeldich, E.; Medalla, M.; Koo, B.-B.; Moore, T. L.
10.1101/2024.11.14.623673 — neuroscience — Posted on 2024-11-14
2695 YORU: social behavior detection based on user-defined animal appearance using deep learning
YAMANOUCHI, H. M.; Takeuchi, R. F.; Chiba, N.; Hashimoto, K.; Shimizu, T.; Tanaka, R.; Kamikouchi, A.
10.1101/2024.11.12.623320 — neuroscience — Posted on 2024-11-14
2696 Transient upregulation of procaspase-3 during oligodendrocyte fate decisions
Kamen, Y.; Chapman, T. W.; Piedra, E. T.; Ciolkowski, M. E.; Hill, R. A.
10.1101/2024.11.13.623446 — neuroscience — Posted on 2024-11-14
2703 Curcumin attenuates microglia-mediated chronic neuropathic pain through CDK5 /p35 signaling pathway
Tong, F.; Zhao, l.; Yang, Y.; Zhang, Z.; Liu, L.; Wu, Y.; Di, X.; Zhang, Z.; Xu, X.; Zhang, Y.; Shen, Y.; Yu, l.; Zhang, l.; Yao, Y.; Zhang, H.
10.1101/2024.11.13.623498 — neuroscience — Posted on 2024-11-14
2705 Orchestrating the Acquisition of Oligodendrocyte Precursor Cell versus Olfactory Bulb Interneuron Fates through Olig1/2 during Mammalian Cortical Gliogenesis and Gliomagenesis
TIAN, Y.; WANG, Z.; YANG, F.; ZHANG, W.; LI, J.; YANG, L.; FU, T.; ZHENG, W.; XU, Z.; MA, T.; YOU, Y.; LI, X.; SONG, J.; XIE, Y.; YANG, Z.; ZHANG, Z.
10.1101/2024.11.11.623106 — neuroscience — Posted on 2024-11-14
2706 Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization
Geng, J.; Voitiuk, K.; Parks, D. F.; Robbins, A.; Spaeth, A.; Sevetson, J. L.; Hernandez, S.; Schweiger, H. E.; Andrews, J. P.; Seiler, S. T.; Elliott, M. A. T.; Chang, E. F.; Nowakowski, T. J.; Currie, R.; Mostajo-Radji, M. A.; Haussler, D.; Sharf, T.; Salama, S. R.; Teodorescu, M.
10.1101/2024.11.14.623530 — neuroscience — Posted on 2024-11-14
2707 Transferrin receptor-mediated transport at the blood-brain barrier is elevated in early development but maintained across adult aging
Torres, V. O.; Pizzo, M. E.; Chan, D.; Dugas, J. C.; Huynh, D.; Joy, D.; Liang, E. K.; Sarrafha, L.; Becerra, I.; Chau, R.; Chew, K. S.; Chow, J.; Earr, T. K.; Khoury, N.; Lechtenberg, K. J.; Leung, A. W.; Nguyen, H. N.; Ojo, E. S.; Roche, E.; Solanoy, H.; Tong, M.; Tong, R. K.; Henne, K.; Lewcock, J. W.; Watts, R. J.; Calvert, M. E.; Thorne, R. G.; Zuchero, J.
10.1101/2024.11.12.623253 — neuroscience — Posted on 2024-11-14
2710 Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model
Balak, C. D.; Schlachetzki, J. C. M.; Lana, A. J.; West, E.; Hong, C.; DuGal, J.; Zhou, Y.; Li, B.; Saisan, P.; Spann, N. J.; Sarsani, V.; Pasillas, M. P.; O'Brien, S.; Gordts, P.; Stevens, B.; Kamme, F.; Glass, C. K.
10.1101/2024.11.12.623296 — neuroscience — Posted on 2024-11-14
2711 Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells
Shah, R.; Yan, W.; Rigal, J.; Mullin, S.; Fan, L.; McGregor, L. M.; Krueger, A.; Renuad, N.; Byrnes, A.; Thomas, J. R.
10.1101/2024.11.14.623654 — biochemistry — Posted on 2024-11-14
2713 Manipulation of Host Cholesterol by SARS-CoV-2
Doyle, A.; Goodson, B. A.; Kolaczkowski, O. M.; Liu, R.; Jia, J.; Wang, H.; Han, X.; Ye, C.; Bradfute, S. B.; Kell, A. M.; Rosas Lemus, M.; Pu, J.
10.1101/2024.11.13.623299 — cell biology — Posted on 2024-11-14
2714 Loss of Cochlin drives impairments in tendon structure and function
Adjei-Sowah, E.; Lecaj, E.; Adhikari, N.; Sensini, C.; Nichols, A. E.; Buckley, M. R.; Loiselle, A. E.
10.1101/2024.11.14.623674 — molecular biology — Posted on 2024-11-14
2717 Rapid and precise quantification of lymphocyte iron content by single cell inductively coupled plasma mass spectrometry
Holdship, P.; Teh, M. R.; Mazurczyk, M.; Chuang, H.-W.; Pironaci, G.; Hilton, R. G.; Price, D.; Wade, J.; Drakesmith, H. F.
10.1101/2024.11.11.623006 — immunology — Posted on 2024-11-14
2718 The impact of FreeSurfer versions on structural neuroimaging analyses of Parkinson's disease
Sokolowski, A.; Bhagwat, N.; Kirbizakis, D.; Chatelain, Y.; Dugre, M.; Poline, J.-B.; Sharp, M.; Glatard, T.
10.1101/2024.11.11.623071 — neuroscience — Posted on 2024-11-14
2719 Resting After Learning Facilitates Memory Consolidation and Reverses Spatial Reorientation Impairments in 'New Surroundings' in 3xTg-AD Mice
Stimmell, A. C.; Alday, L. J.; Diaz, J. M.; Moseley, S. C.; Cushing, S. D.; Salvador, E. M.; Ragsdale, S. M.; Wilber, A. A.
10.1101/2024.11.12.622722 — neuroscience — Posted on 2024-11-14
2720 Downregulation of astrocytic C3 production alleviates neuronal mitochondrial dysfunction in tauopathy models
Lei, C.; Zhang, B.; Tamura, R.; Yamaguchi, J.; Cao, X.; Liu, Y.; Seki, M.; Suzuki, Y.; Suzuki, K.; Tanida, I.; Uchiyama, Y.; Hisatsune, T.
10.1101/2024.11.12.622892 — neuroscience — Posted on 2024-11-14
2722 Peripheral CGRP engages brain-wide electrical network activity of migraine
Johnson, M. S.; Eberle, M.; Hultman, I.; Zhang, X.; Filali, Y.; Hing, B.; Jimenez, A.; Matkovich, M.; Adegboyo, A.; Velamuri, R.; Miller, J.; Chan, K.-S.; Srivastava, S.; Hultman, R.
10.1101/2024.11.14.622885 — neuroscience — Posted on 2024-11-14
2724 Enhancing Gene Set Overrepresentation Analysis with Large Language Models
Zhu, J.; Wang, R. Y.; Wang, X.; Azevedo, R.; Moreno, A.; Kuhn, J. A.; Khan, Z.
10.1101/2024.11.11.621189 — bioinformatics — Posted on 2024-11-14
2727 Identification and characterization of substrate- and product-selective nylon hydrolases
Drufva, E.; Cahill, J. F.; Saint-Vincent, P.; Williams, A.; Bocharova, V.; Capra, N.; Meilleur, F.; Carper, D.; Bourgery, C.; Miyazaki, K.; Yonemura, M.; Shiraishi, Y.; Parks, J.; Zhou, M.; Dishner, I.; Foster, J.; Koehler, S.; Valentino, H.; Sedova, A.; Kertesz, V.; Vasileva, D.; Hochanadel, L.; Figg, A.; Negoro, S.; Kato, D.-i.; Chen, S. H.; Michener, J. K.
10.1101/2024.11.14.623603 — biochemistry — Posted on 2024-11-14
2728 RhoA Allosterically Activates Phospholipase Cε via its EF Hands
Ohri, V.; Samassekou, K.; Muralidharan, K.; Garland-Kuntz, E. E.; Fisher, I. J.; Hogan, W. C.; Davis, B. M.; Lyon, A.
10.1101/2024.11.14.623250 — biochemistry — Posted on 2024-11-14
2731 Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences
Miedlar, E.; Hamilton, G. E.; Witus, S. R.; Gonske, S. J.; Riffle, M.; Zelter, A.; Klevit, R. E.; Asbury, C. L.; Dimitrova, Y. N.; Davis, T. N.
10.1101/2024.11.13.623448 — biochemistry — Posted on 2024-11-14
2732 Interlaboratory comparison of standardised metabolomics and lipidomics analyses in human and rodent blood using the MxP(R) Quant 500 kit
Zararsiz, G. E.; Lintelmann, J.; Cecil, A.; Kirwan, J.; Poschet, G.; Gegner, H. M.; Schuchardt, S.; Guan, X. L.; Saigusa, D.; Wishart, D.; Zheng, J.; Mandal, R.; Adams, K.; Thompson, J. W.; Snyder, M. P.; Contrepois, K.; Chen, S.; Ashrafi, N.; Akyol, S.; Yilmaz, A.; Graham, S. F.; O'Connell, T. M.; Kalecky, K.; Bottiglieri, T.; Limonciel, A.; Pham, H. T.; Koal, T.; Adamski, J.; Kastenmüller, G.
10.1101/2024.11.13.619447 — biochemistry — Posted on 2024-11-14
2733 Activity-based selection for enhanced base editor mutational scanning
Kaplan, E. G.; Steger, R. J.; Shah, S. T.; Drepanos, L. M.; Griffith, A. L.; Reint, G.; Doench, J. G.
10.1101/2024.11.12.622254 — genetics — Posted on 2024-11-14
2734 Lethal Plague Outbreaks in Lake Baikal Hunter-gatherers 5500 Years Ago
Macleod, R.; Seersholm, F. V.; de Sanctis, B.; Lieverse, A.; Timpson, A.; Stenderup, J.; Gaunitz, C.; Vinner, L.; Schulting, R.; Goriunova, O. I.; Bazaliiskii, V. I.; Vasiliev, S. V.; Jessup, E.; Wang, Y.; Thomas, M. G.; Corbett-Detig, R.; Iversen, A. K. N.; Weber, A.; Sikora, M.; Willerslev, E.
10.1101/2024.11.13.623490 — genetics — Posted on 2024-11-14
2736 Unveiling novel mechanisms of strobilurin resistance in the cacao pathogen Moniliophthora perniciosa
do Prado, P. F. V.; Mendes, C. V. C.; Pires, B. A.; Fiorin, G. L.; Mieczkowski, P.; Pereira, G. A. G.; Teixeira, P. J. P. L.; Thomazella, D. P. d. T.
10.1101/2024.11.14.623591 — microbiology — Posted on 2024-11-14
2739 Sequence specificity of an essential nuclear localization sequence in Mcm3
Wang, Z.; Zhang, Y. J.; Zhang, Q.-y.; Bilsborrow, K.; Leslie, M.; Suhandynata, R. T.; Zhou, H.
10.1101/2024.11.14.623588 — microbiology — Posted on 2024-11-14
2740 The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates in the gluconeogenic direction in cellulo under in vivo-like conditions
Plazolles, N.; Kulyk, H.; Cahoreau, E.; Biran, M.; Wargnies, M.; Pineda, E.; El Kadri, M.; Rimoldi, A.; Herve, P.; Asencio, C.; Riviere, L.; Michels, P. A.; Inaoka, D.; Tetaud, E.; Portais, J.-C.; Bringaud, F.
10.1101/2024.11.14.623581 — microbiology — Posted on 2024-11-14
2741 Vibrio cholerae lineage and pangenome diversity varies geographically across Bangladesh over one year
Qin, C.; Lypaczewski, P.; Sayeed, M. A.; Cuenod, A. C.; Brinkley, L.; Creasy-Marrazzo, A.; Cato, E. T.; Islam, K.; Khan, A. I.; Khabir, M. I. U.; Bhuiyan, T. R.; Begum, Y.; Qadri, F.; Nelson, E. J.; Shapiro, B. J.
10.1101/2024.11.12.623281 — microbiology — Posted on 2024-11-14
2745 Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes
Chowdhury, J. M.; Chacin Ruiz, E. A.; Ohr, M. P.; Swindle-Reilly, K. E.; Ford Versypt, A. N.
10.1101/2023.05.05.539491 — systems biology — Posted on 2024-11-14
2747 PYR1 biosensor-driven genome-wide CRISPR screens for improved monoterpenoid production in Kluyveromyces marxianus
Robertson, N. R.; Lenert-Mondou, C.; Leonard, A. C.; Tafrishi, A.; Carrera, S.; Lee, S.; Aguilar, Y.; Zamora, L. S.; Nguyen, T.; Beltran, J.; Li, M.; Cutler, S. R.; Whitehead, T. A.; Wheeldon, I.
10.1101/2024.11.14.623641 — synthetic biology — Posted on 2024-11-14
2749 Cell-Free Optimized Production of Protoporphyrin IX
Garcia, D. C.; Davies, J. P.; Rhea, K.; Lee, M. S.; Lux, M. W.
10.1101/2023.12.28.573540 — bioengineering — Posted on 2024-11-14
2750 Sulfur-species in Zinc-specific Condylar Zones of a Rat Temporomandibular Joint
Lee, B. H.; Yang, Z.; Ho, T. J.; Wang, Y.; Tamura, N.; Webb, S.; Bone, S.; Ho, S. P.
10.1101/2024.11.11.623079 — bioengineering — Posted on 2024-11-14
2752 Computational Design of Metallohydrolases
Kim, D.; Woodbury, S. M.; Ahern, W.; Kalvet, I.; Hanikel, N.; Salike, S.; Pellock, S. J.; Lauko, A.; Hilvert, D.; Baker, D.
10.1101/2024.11.13.623507 — biochemistry — Posted on 2024-11-14
2754 scPrediXcan integrates advances in deep learning and single-cell data into a powerful cell-type-specific transcriptome-wide association study framework
Zhou, Y.; Adeluwa, T.; Zhu, L.; Salazar, S.; Sumner, S.; Kim, H.; Gona, S.; Nyasimi, F.; Kulkarni, R.; Powell, J.; Madduri, R.; Liu, B.; Chen, M.; Im, H. K.
10.1101/2024.11.11.623049 — genetics — Posted on 2024-11-14
2755 Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression
Nshanian, M.; Gruber, J. J.; Geller, B. S.; Chleilat, F.; Lancaster, S.; White, S. M.; Alexandrova, L.; Camarillo, J. M.; Kelleher, N. L.; Zhao, Y.; Snyder, M. P.
10.1101/2024.01.11.575111 — genetics — Posted on 2024-11-14
2757 Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice
Nash, A. N.; Shakeshaft, M.; Bouaichi, C. G.; Odegaard, K. E.; Needham, T.; Bauer, M.; Bertram, R.; Vincis, R.
10.1101/2024.04.27.591293 — neuroscience — Posted on 2024-11-14
2758 Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish
Shanbhag, R.; Zoidl, G. S. O.; Nakhuda, F.; Sabour, S.; Naumann, H.; Zoidl, C.; Bahl, A.; Tabatabaei, N.; Zoidl, G. R.
10.1101/2024.10.01.616190 — neuroscience — Posted on 2024-11-14
2761 Inactivity-mediated molecular adaptations: insights from a pre-clinical model of physical activity reduction
Meyer, A.; Kim, N.; Nguyen, M.; Misch, M.; Marmo, K.; Dowd, J.; Will, C.; Janosevic, M.; Stephenson, E. J.
10.1101/2024.09.17.613551 — physiology — Posted on 2024-11-14
2766 Blood cultures contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and virulence
Fleres, G.; Cheng, S.; Badrane, H.; Dupont, C. L.; Espinoza, J.; Abbey, D.; Driscoll, E.; Newbrough, A.; Hao, B.; Mansour, A.; Nguyen, M. H.; Clancy, C. J.
10.1101/2024.10.16.618724 — microbiology — Posted on 2024-11-14
2769 Protocol for open-source Automated Universal high-content multiplex fluorescence for RNA in situ Analysis (AURA)
Descarpentrie, J.; Bernard, F.; Souleyreau, W.; Brisson, L.; Mathivet, T.; Pateras, I. S.; Martin, O. C.; Lopez Chiloeches, M.; Frisan, T.
10.1101/2024.06.28.601140 — cell biology — Posted on 2024-11-14
2771 A generative foundation model for antibody sequence understanding
Barton, J.; Gaspariunas, A.; Yadin, D. A.; Dias, J.; Nice, F. L.; Minns, D. H.; Snudden, O.; Povall, C.; Valle Tomas, S.; Dobson, H.; Farmery, J. H.; Leem, J.; Galson, J. D.
10.1101/2024.05.22.594943 — bioinformatics — Posted on 2024-11-14
2772 The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ
Martin, P. R.; Nieminuszczy, J.; Kozik, Z.; Jakub, N.; Lecot, M.; Vorhauser, J.; Lane, K. A.; Kanellou, A.; Mansfeld, J.; Pearl, L. H.; Oliver, A.; Downs, J. A.; Chaudhary, J.; Day, M.; Niedzwiedz, W.
10.1101/2024.11.12.621593 — molecular biology — Posted on 2024-11-14
2773 Unveiling Multi-level and Multi-modal Semantic Representations in the Human Brain using Large Language Models
Nakagi, Y.; Matsuyama, T.; Koide-Majima, N.; Yamaguchi, H. Q.; Kubo, R.; Nishimoto, S.; Takagi, Y.
10.1101/2024.02.06.579077 — neuroscience — Posted on 2024-11-14
2777 Accumulation of Dietary and Non-Enzymatic Oxysterols in Preeclamptic Placentas: Insights into Cholesterol Dynamics in Pregnancy Complications
Zou, L.; Maldonado-Pereira, L.; Ticiani, E.; Sethuraman, V.; Olomu, N.; Long, R.; Veiga-Lopez, A.; Medina-Meza, I. G.
10.1101/2024.11.13.623499 — physiology — Posted on 2024-11-14
2778 Effects of maternal exercise modes on infant cord blood proteome
Jevtovic, F.; Wisseman, B.; Jahan, F.; Claiborne, A.; Collier, D. N.; DeVente, J. E.; Mouro, S.; Zeczycki, T.; Goodyear, L. J.; May, L. E.
10.1101/2024.11.11.623083 — physiology — Posted on 2024-11-14
2780 Brain Aging Among Individuals with Classical Trigeminal Neuralgia
Cruz-Almeida, Y.; Valdes-Hernandez, P. A.; Liang, Y.; Ding, M.; Neubert, J. K.
10.1101/2024.11.13.623489 — neuroscience — Posted on 2024-11-14
2783 Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids
Karakulak, T.; Zajac, N.; Bolck, H. A.; Bratus-Neuenschwander, A.; Zhang, Q.; Qi, W.; Basu, D.; Oltra, T. C.; Rehrauer, H.; von Mering, C.; Moch, H.; Kahraman, A.
10.1101/2024.03.15.585271 — cancer biology — Posted on 2024-11-14
2785 Metabolomic profile for understanding heart failure classifications
Kozhevnikova, M. V.; Belenkov, Y. N.; Shestakova, K. M.; Ageev, A. A.; Markin, P. A.; Kakotkina, A. V.; Korobkova, E. O.; Moskaleva, N. E.; Kuznetsov, I. V.; Khabarova, N. V.; Kukharenko, A. V.; Appolonova, S. A.
10.1101/2024.11.13.623517 — biochemistry — Posted on 2024-11-14
2787 Comparative population genomics unveils congruent secondary suture zone in Southwest Pacific Hydrothermal Vents
Tran Lu Y, A.; Ruault, S.; Daguin-Thiebaut, C.; Le Port, A.-S.; Ballenghien, M.; Castel, J.; Gagnaire, P.-A.; Bierne, N.; Arnaud-Haond, S.; Poitrimol, C.; Thiebaut, E.; Lallier, F.; Broquet, T.; Jollivet, D.; Bonhomme, F.; Hourdez, S.
10.1101/2024.05.31.596862 — evolutionary biology — Posted on 2024-11-14
2791 Characteristics of early career health researchers and experiences of burnout during the COVID-19 pandemic in Canada
Hewko, S.; Kowalec, K.; Anderson, L.; Mulvihill, E. E.; Aristizabal, M.; Ciernia, A. V.; Dhillon, S.; Dufour, A.; Lim, G. E.; Rousseaux, M.; Saleem, A.; Daraz, L.; Lam, G.; Association of Canadian Early Career Health Researchers,
10.1101/2024.11.13.622718 — scientific communication and education — Posted on 2024-11-14
2792 Comparing machine learning models for predicting mutation status in Acute Myeloid Leukemia patients using RNA-seq data
Silva, R.; Riedel, C.; Reboul, J.; Guibert, B.; Ruffle, F.; Gallopin, M.; Gilbert, N.; Boureux, A.; Commes, T.
10.1101/2024.11.13.623391 — bioinformatics — Posted on 2024-11-14
2793 Dysregulation of synaptic-related genes within neuroimmune networks of peripheral blood mononuclear cells in major depressive disorder
Adri, A.; Nobile, A. L.; de Alburquerque, D. G.; Barcelos, P. M.; do Vale, F.; Bahia, I. A.; Freire, P.; Nava, R. G.; Correa, Y. L. G. C.; Cabral-Miranda, G.; Dalmolin, R.; Schimke, L.; Fonseca, D.; Filgueiras, I. S.; Nakaya, H.; Rezende, R. M.; Dias, H. D.; Cabral-Marques, O.
10.1101/2024.11.13.623441 — bioinformatics — Posted on 2024-11-14
2794 Effect of quantified cranial osteopathic manipulation on wild type and transgenic rat models of Alzheimer's disease
Hines, D.; Tobey, H.; Dugan, P.; Boehringer, S.; Helm, R.; Anandakrishnan, R.; Werre, S.; VandeVord, P.; Costa, B.
10.1101/2024.11.05.621645 — bioengineering — Posted on 2024-11-14
2795 Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision
Seltzer, R.; Zer Eshel, G.; Yinon, O.; Hafani, A.; Eitan, O.; Matveev, S.; Levedev, G.; Davidovitz, M.; Ben Tov, T.; Sharabi, G.; Shapira, Y.; Shvil, N.; Atallah, I.; Hadad, S.; Ment, D.; Hadany, L.; Yovel, Y.
10.1101/2024.11.06.622209 — animal behavior and cognition — Posted on 2024-11-14
2797 New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C CDH1:EMI1 complex
Hoefler, A.; Yu, J.; Yang, J.; Zhang, Z.; Chang, L.; McLaughlin, S. H.; Grime, G. W.; Garman, E. F.; Boland, A.; Barford, D.
10.1101/2023.08.31.555674 — cell biology — Posted on 2024-11-14
2799 Absolute number of three populations of interneurons and all GABAergic synapses in the human hippocampus
Takacs, V.; Papp, P.; Orosz, A.; Bardoczi, Z.; Zsoldos, T.; Zicho, K.; Watanabe, M.; Magloczky, Z.; Gombas, P.; Freund, T. F.; Nyiri, G.
10.1101/2023.09.26.559559 — neuroscience — Posted on 2024-11-14
2800 Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles
Singh, N. J.; Olofsson, R.; van der Meiden, A. J.; Lopez-Peinado, A.; Mansson, J.
10.1101/2024.11.02.621680 — ecology — Posted on 2024-11-14
2802 Resource landscape shapes the composition and stability of the human vaginal microbiota
Kamiya, T.; Sofonea, M. T.; France, M.; Tessandier, N.; Bravo, I. G.; Murall, C. L.; Ravel, J.; Alizon, S.
10.1101/2024.11.12.622464 — microbiology — Posted on 2024-11-14
2804 Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders
Jamieson, A. J.; Steward, T.; Davey, C. G.; Ince, S.; Agathos, J. A.; Moffat, B. A.; Glarin, R. K.; Felmingham, K. L.; Harrison, B. J.
10.1101/2024.11.06.622349 — neuroscience — Posted on 2024-11-14
2806 Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice
Sterrett, J. D.; Quinn, K. D.; Doenges, K. A.; Nusbacher, N.; Levens, C. L.; Armstrong, M. L.; Reisdorph, R. M.; Smith, H.; Saba, L. M.; Kuhn, K. A.; Lozupone, C.; Reisdorph, N.
10.1101/2024.07.11.603097 — systems biology — Posted on 2024-11-14
2811 AllTheBacteria - all bacterial genomes assembled, available and searchable
Hunt, M.; Lima, L.; Anderson, D.; Hawkey, J.; Shen, W.; Lees, J.; Iqbal, Z.
10.1101/2024.03.08.584059 — bioinformatics — Posted on 2024-11-14
2812 Logic-based modeling of biological networks with Netflux
Clark, A. P.; Chowkwale, M.; Paap, A.; Dang, S.; Saucerman, J. J.
10.1101/2024.01.11.575227 — bioengineering — Posted on 2024-11-14
2813 Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA
Kania, E. E.; Fenix, A.; Marciniak, D. M.; Lin, Q.; Bianchi, S.; Hristov, B.; Li, S.; Camplisson, C. K.; Fields, R.; Beliveau, B. J.; Schweppe, D. K.; Noble, W. S.; Ong, S.-E.; Bertero, A.; Murry, C. E.; Shechner, D. M.
10.1101/2024.11.05.622011 — genomics — Posted on 2024-11-14
2816 Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects
Bozon, K.; Cuny, H.; Sheng, D. Z.; Martin, E. M.; Sipka, A.; Young, P.; Humphreys, D. T.; Dunwoodie, S. L.
10.1101/2024.05.07.592899 — developmental biology — Posted on 2024-11-14
2817 Membrane potential mediates the cellular response to mechanical pressure
Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J.; Neliat, A. R.; Schuttler, J.; Su, D.; Dupre, C.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.
10.1101/2023.11.02.565386 — cell biology — Posted on 2024-11-14
2818 A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope
Srivastava, N.; Vomund, A.; Peterson, O.; Abousaway, O.; Li, T.; Kain, L.; Stone, P.; Clement, C.; Sharma, S.; Zhang, B.; Liu, C.; Joglekar, A.; Campisi, L.; Hsieh, C.-S.; Santambrogio, L.; Teyton, L.; Arbelaez, A. M.; Lichti, C.; Wan, X.
10.1101/2024.11.07.622538 — immunology — Posted on 2024-11-14
2819 Chemogenetic stimulation of phrenic motor output and diaphragm activity
Benevides, E. S.; Thakre, P. P.; Rana, S.; Sunshine, M. D.; Jensen, V. N.; Oweiss, K.; Fuller, D.
10.1101/2024.04.12.589188 — neuroscience — Posted on 2024-11-13
2821 Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI
Autio, J. A.; Uematsu, A.; Ikeda, T.; Ose, T.; Hou, Y.; Magrou, L.; Kimura, I.; Ohno, M.; Murata, K.; Coalson, T.; Kennedy, H.; Glasser, M. F.; Van Essen, D. C.; Hayashi, T.
10.1101/2024.09.27.615294 — neuroscience — Posted on 2024-11-14
2822 Psychedelic 5-HT2A receptor agonism: neuronal signatures and altered neurovascular coupling.
Padawer-Curry, J. A.; Krentzman, O. J.; Kuo, C.-C.; Wang, X.; Bice, A. R.; Nicol, G. E.; Snyder, A. Z.; Siegel, J. S.; McCall, J. G.; Bauer, A. Q.
10.1101/2023.09.23.559145 — neuroscience — Posted on 2024-11-14
2825 The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ
Martin, P. R.; Nieminuszczy, J.; Kozik, Z.; Jakub, N.; Lecot, M.; Vorhauser, J.; Lane, K. A.; Kanellou, A.; Mansfeld, J.; Pearl, L. H.; Oliver, A.; Downs, J. A.; Chaudhary, J.; Day, M.; Niedzwiedz, W.
10.1101/2024.11.12.621593 — molecular biology — Posted on 2024-11-13
2827 A Chaperonin Complex Regulates Organelle Proteostasis in Malaria Parasites
Tissawak, A.; Rosin, Y.; Shahar, M.; Trabelsi, N.; Schueler-Furman, O.; Johnson, S. M.; Florentin, A.
10.1101/2024.11.13.623364 — microbiology — Posted on 2024-11-13
2828 Telomeric transposons are pervasive in linear bacterial genomes
Hsieh, S.-C.; Fülöp, M.; Schargel, R.; Petassi, M. T.; Barabas, O.; Peters, J. E.
10.1101/2024.11.13.623437 — microbiology — Posted on 2024-11-13
2830 Structural basis of the catalytic and allosteric mechanism of bacterial acetyltransferase PatZ
Park, J. B.; Lee, G.; Han, Y.-Y.; Kim, D.; Heo, K.; Kim, J.; Park, J.; Yun, H.; Lee, C. W.; Cho, H.-S.; Kim, J.-S.; Steinegger, M.; Seok, Y.-J.; roh, s. h.
10.1101/2024.11.12.623305 — biochemistry — Posted on 2024-11-13
2831 Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal Domain
Li, P.; Faraone, J. N.; Hsu, C. C.; Chamblee, M.; Liu, Y.; Zheng, Y.-M.; Xu, Y.; Carlin, C.; Horowitz, J. C.; Mallampalli, R. K.; Saif, L. J.; Oltz, E. M.; Jones, D.; Li, J.; Gumina, R. J.; Bednash, J. S.; Xu, K.; Liu, S.-L.
10.1101/2024.11.12.623078 — molecular biology — Posted on 2024-11-13
2834 Optimisation of single-nuclei isolation and RNA sequencing of parasitic nematodes
Buddenborg, S. K.; Morrison, A.; Fletcher, A. C.; Kieninger, M. R.; Ng, B. L.; Maitland, K.; McIntyre, J.; Hart, E.; Bartley, D.; Duque-Correa, M. A.; Doyle, S. R.
10.1101/2024.11.13.623282 — molecular biology — Posted on 2024-11-13
2836 Metaproteomics reveals age-specific alterations of gut microbiome in hamsters with SARS-CoV-2 infection
Creskey, M.; Angulo, F. S.; Wu, Q.; Tamming, L.; Fekete, E.; Cheng, K.; Ning, Z.; Wang, A.; Rodrigues, P. B.; Rodovalho, V. d. R.; Vinolo, M. A. R.; Figeys, D.; Li, X.; Trottein, F.; Zhang, X.
10.1101/2024.11.12.623292 — microbiology — Posted on 2024-11-13
2837 Mapping Plasmodium transitions and interactions in the Anopheles female
Yan, Y.; Cheung, E.; Verzier, L. H.; Appetecchia, F.; March, S.; Craven, A. R.; Du, E.; Probst, A. S.; Rinvee, T. A.; de Vries, L. E.; Kauffman, J.; Bhatia, S. N.; Nelson, E.; Singh, N.; Peng, D.; Shaw, W. R.; Catteruccia, F.
10.1101/2024.11.12.623125 — microbiology — Posted on 2024-11-13
2839 Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection
Guo, Q.; Parikh, K.; Zhang, J.; Brinkley, A.; Chen, G.; Jakramonpreeya, N.; Zhen, A.; An, D. S.
10.1101/2024.11.13.623476 — microbiology — Posted on 2024-11-13
2841 Vibrio cholerae lineage and pangenome diversity varies geographically across Bangladesh over one year
Qin, C.; Lypaczewski, P.; Sayeed, M. A.; Brinkley, L.; Creasy-Marrazzo, A.; Cato, E. T.; Islam, K.; Khabir, M. I. U.; Bhuiyan, T. R.; Begum, Y.; Qadri, F.; Khan, A. I.; Nelson, E. J.; Shapiro, B. J.
10.1101/2024.11.12.623281 — microbiology — Posted on 2024-11-13
2843 Synergistic effects of tRNA modification defects in Escherichia coli K12.
Bacusmo, J. o. M.; Babor, J.; Hu, J.; Cao, B.; Kellner, S.; Szkrybalo, S.; Yuan, Y.; Sander, S.; Kuipers, P.; Mott, M.; Mori, H.; Dedon, P.; de Crecy-Lagard, V.
10.1101/2024.11.12.622971 — microbiology — Posted on 2024-11-13
2844 SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness.
Zhou, Y.; Ahearn, Y. P.; Lokugamage, K. G.; Alvarado, R. E.; Estes, L. K.; Meyers, W. M.; McLeland, A. M.; Morgan, A. L.; Murray, J. T.; Walker, D. H.; Johnson, B. A.; Routh, A. L.; Menachery, V. D.
10.1101/2024.11.11.622995 — microbiology — Posted on 2024-11-13
2845 Discovery of lydiamycin A biosynthetic gene cluster in the plant pathogen Rhodococcus fascians guides structural revision and identification of molecular target
Ford, J. J.; Santos-Aberturas, J.; Hems, E. S.; Sallmen, J. W.; Bögeholz, L. A. K.; Polturak, G.; Osbourn, A.; Wright, J. A.; Rodnina, M. V.; Vereecke, D.; Francis, I. M.; Truman, A. W.
10.1101/2024.11.13.623425 — microbiology — Posted on 2024-11-13
2846 COMPARATIVE CHARACTERISTICS OF THE ACCUMULATION OF DIFFERENT VARIANTS OF THE SARS-COV-2 VIRUS (WUHAN, DELTA, OMICRON) IN THE ORGANS OF MODEL ANIMALS
Chernov, A.; Kazakov, V.; Gogleva, I.; Savenko, S.; Schukina, V.; Loginova, S.; Smirnov, I.; Borisevich, S.; Telegin, G.; Belogurov, A.
10.1101/2024.11.12.623177 — pathology — Posted on 2024-11-13
2849 Inflammation-Induced Claudin-2 Upregulation Limits Pancreatitis Progression by Enhancing Tight Junction-Controlled Pancreatic Ductal Transport
Kesaraju, S.; Li, Y.; Xing, J.; Tracy, M.; Wannemo, K.; Holder, A.; Zhao, P.; Khan, M. A.; Kainov, J.; Rana, N.; Sidahmed, M.; Hyoju, S.; Smith, L.; Matthews, J.; Tay, S.; Khalili-Araghi, F.; Rana, M.; Oakes, S.; Shen, L.; Weber, C.
10.1101/2023.09.01.555960 — pathology — Posted on 2024-11-13
2850 Palatal segment contributions to midfacial anterior-posterior growth
Welsh, I. C.; Feiler, M.; Lipman, D.; Mormile, I.; Hansen, K.; Percival, C. J. C.
10.1101/2023.10.03.560703 — developmental biology — Posted on 2024-11-13
2853 Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish
Lopez-Blanch, L.; Rodriguez-Marin, C.; Mantica, F.; Iniguez, L. P.; Permanyer, J.; Kita, E. M.; Mackensen, T.; Codina-Tobias, M.; Romero-Ferrero, F.; Fernandez-Albert, J.; Cuadrado, M.; Bustelo, X. R.; de Polavieja, G.; Irimia, M.
10.1101/2024.10.23.619860 — molecular biology — Posted on 2024-11-13
2856 Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata)
Peichl, L.; Meimann, S.; Solovei, I.; Gügel, I. L.; Geiger, C.; Schauerte, N.; Gozdziewska-Harłajczuk, K.; Kleckowska-Nawrot, J. E.; Wibbelt, G.; Haverkamp, S.
10.1101/2024.11.09.622767 — zoology — Posted on 2024-11-13
2857 Clonal evolution mediates Menin-inhibitor resistance in KMT2A-rearranged leukemias.
Mahdavi, L.; Goodrow, H.; Alikarami, F.; Lenard, A.; Riedel, S. S.; Libbrecht, C.; Bowser, I.; Tasian, S. K.; Falkenstein, C.; Manning, B.; Skuli, S.; Carroll, M. P.; Wertheim, G.; Cai, S.; McGeehan, G.; Xie, H. M.; Bernt, K. M.
10.1101/2023.03.16.532874 — cancer biology — Posted on 2024-11-13
2859 Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors
Vorontsov, I. E.; Kozin, I.; Abramov, S.; Boytsov, A.; Jolma, A.; Albu, M.; Ambrosini, G.; Faltejskova, K.; Gralak, A. J.; Gryzunov, N.; Inukai, S.; Kolmykov, S.; Kravchenko, P.; Kribelbauer-Swietek, J. F.; Laverty, K. U.; Nozdrin, V.; Patel, Z. M.; Penzar, D.; Plescher, M.-L.; Pour, S. E.; Razavi, R.; Yang, A. W. H.; Yevshin, I.; Zinkevich, A.; Weirauch, M. T.; Bucher, P.; Deplancke, B.; Fornes, O.; Grau, J.; Grosse, I.; Kolpakov, F. A.; The Codebook/GRECO-BIT Consortium, ; Makeev, V. J.; Hughes, T. R.; Kulakovskiy, I. V.
10.1101/2024.11.11.619379 — bioinformatics — Posted on 2024-11-13
2860 Fine-scale oceanographic processes shape marine biodiversity patterns in the Galapagos Islands
Holman, L. E.; Pazmino, D. A.; Gopalakrishnan, S.; Forryan, A.; Hearn, A. R.; Naveira-Garabato, A. C.; Rius, M.
10.1101/2024.03.06.583537 — ecology — Posted on 2024-11-13
2862 Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes
Aseem, S. O.; Way, G.; Wang, J.; Zhao, D.; Tai, Y.-L.; Gurley, E.; Zeng, J.; Wang, X.; Hylemon, P. B.; Huebert, R. C.; Sanyal, A. J.; Zhou, H.
10.1101/2024.11.06.621880 — cell biology — Posted on 2024-11-13
2865 The dorsal fan-shaped body is a neurochemically heterogeneous sleep-regulating center in Drosophila
Jones, J. D.; Holder, B. L.; Montgomery, A. C.; McAdams, C. V.; He, E.; Burns, A. E.; Eiken, K. R.; Vogt, A.; Velarde, A. I.; Elder, A. J.; McEllin, J. A.; Dissel, S.
10.1101/2024.04.10.588925 — neuroscience — Posted on 2024-11-13
2866 Human skin rejuvenation via mRNA
Li, L.; Tang, Z.; Portillo, X.; Arora, R.; Yang, M.; Mintzer, E.; Han, P.; Zhang, Z.; Majewski, D. D.; Titelman, A. A.; Plesa, A. M.; Shadpour, M.; McNamee, S. M.; Zheng, Y.; Li, X.; Tam, J.; McGee, J.; Sol, S.; Boncimino, F.; Zhang, Y. S.; Mandinova, A.; Murphy, G. F.; Kupper, T. S.; Ma, S.; Church, G.
10.1101/2024.11.12.623261 — synthetic biology — Posted on 2024-11-13
2867 TreePPL: A Universal Probabilistic Programming Language for Phylogenetics
Senderov, V. E.; Kudlicka, J.; Lunden, D.; Palmkvist, V.; Braga, M. P.; Granqvist, E.; caylak, G.; Virgoulay, T.; Broman, D.; Ronquist, F. E.
10.1101/2023.10.10.561673 — bioinformatics — Posted on 2024-11-13
2871 Multimodal state-dependent connectivity analysis of arousal and autonomic centers in the brainstem and basal forebrain
Pourmotabbed, H.; Martin, C. G.; Goodale, S. E.; Doss, D. J.; Wang, S.; Bayrak, R. G.; Kang, H.; Morgan, V. L.; Englot, D. J.; Chang, C.
10.1101/2024.11.11.623092 — neuroscience — Posted on 2024-11-13
2873 Celldetective: an AI-enhanced image analysis tool for unraveling dynamic cell interactions
Torro, R.; Diaz Bello, B.; El Arawi, D.; Dervanova, K.; Ammer, L.; Dupuy, F.; Chames, P.; Sengupta, K.; Limozin, L.
10.1101/2024.03.15.585250 — bioinformatics — Posted on 2024-11-13
2874 invertiaDB: A Database of Inverted Repeats Across Organismal Genomes
Provatas, K.; Chantzi, N.; Patsakis, M.; Nayak, A.; Mouratidis, I.; Pavlopoulos, G.; Georgakopoulos-Soares, I.
10.1101/2024.11.11.622808 — genomics — Posted on 2024-11-13
2875 Draft genome sequence of the glasshouse-potato aphid Aulacorthum solani
Torres, J.; Rozo-Lopez, P.; Brewer, W.; Saleh Ziabari, O.; Parker, B. J.
10.1101/2024.11.12.623246 — genomics — Posted on 2024-11-13
2877 Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance
Fellas, A.; Pidoux, A. L.; Tong, P.; Hewes, H. H.; Wallace, E. C.; Allshire, R. C.
10.1101/2024.11.13.623381 — cell biology — Posted on 2024-11-13
2878 A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
Pang, J.; Al-Ani, A. H.; Patel, K. M.; Young, S. N.; Kong, I.; Chen, J.-j.; Barrios, M.; Rickard, J. A.; Chen, S.; Foroughi, S.; Cawthorne, W.; Jacobsen, A. V.; Jois, A.; Weir, A. L.; Whitehead, L. W.; Rajasekhar, P.; Horne, C. R.; Azeez, I.; Tan, T.; Liang, W.; Sivanesan, S.; Metz, A.; Patwardhan, A.; Shea, N.; Iyngkaran, G.; Schneider, D.; Elford, A. T.; Beattie, W.; Macrae, F.; Liccardi, G.; Walczak, H.; Zhang, Y.; Sieber, O. M.; Spelman, T.; Giulino-Roth, L.; Hawkins, E. D.; Rogers, K. L.; Bowden, R.; Nicholson, S. E.; Lawlor, K. E.; Christensen, B.; Samson, A. L.; Vince, J. E.; Murphy, J.
10.1101/2024.11.13.623307 — cell biology — Posted on 2024-11-13
2880 Serum metabolome profiling in patients with mild cognitive impairment reveals sex differences in lipid metabolism
Diaz Escarcega, R.; M J, V. K.; Kyriakopoulos, V. E.; Ortiz, G. J.; Gusdon, A. M.; Fan, H.; Peesh, P.; Blasco Conesa, M. P.; Delevati Colpo, G.; Ahnstedt, H. W.; Couture, L.; Kim, S. H.; Hinojosa, M.; Farrell, C. M.; Marrelli, S. P.; Urayama, A.; Ganesh, B. P.; Schulz, P. E.; McCullough, L. D.; Tsvetkov, A. S.
10.1101/2024.11.11.623108 — neuroscience — Posted on 2024-11-13
2881 Indecision and recency-weighted evidence integration in non-clinical and clinical settings
del Rio, M.; Trudel, N.; Prabhu, G.; Hunt, L. T.; Moutoussis, M.; Dolan, R. J.; Hauser, T. U.
10.1101/2024.11.11.622934 — neuroscience — Posted on 2024-11-13
2888 BiaPy: Accessible deep learning on bioimages
Franco-Barranco, D.; Andres-San Roman, J. A.; Hidalgo-Cenalmor, I.; Backova, L.; Gonzalez-Marfil, A.; Caporal, C.; Chessel, A.; Gomez-Galvez, P.; Escudero, L. M.; Wei, D.; Munoz-Barrutia, A.; Arganda-Carreras, I.
10.1101/2024.02.03.576026 — bioinformatics — Posted on 2024-11-13
2889 A Cardiac Transcriptional Enhancer is Repurposed During Regeneration to Activate an Anti-proliferative Program
Rao, A.; Russell, A.; Segura-Bermudez, J.; Franz, C.; Dockery, R.; Blatnik, A.; Panten, J.; Zevallos, M.; McNulty, C.; Pietrzak, M.; Goldman, J. A.
10.1101/2023.06.30.547239 — developmental biology — Posted on 2024-11-13
2890 A lipid signature of BAK-driven apoptotic pore formation
Uren, R. T.; Ritchie, M. E.; Wong, A. W.; Ludeman, J. P.; Uno, E.; Narayana, V. K.; De Souza, D. P.; Sviridov, D.; Kluck, R. M.
10.1101/2024.10.16.618570 — cell biology — Posted on 2024-11-13
2892 Neutralizing human monoclonal antibodies that target the PcrV component of the Type III Secretion System of Pseudomonas aeruginosa act through distinct mechanisms
Desveaux, J.-M.; Faudry, E.; Contreras-Martel, C.; Cretin, F.; Dergan-Dylon, L. S.; Amen, A.; Bally, I.; Tardivy-Casemajor, V.; Chenavier, F.; Fouquenet, D.; Caspar, Y.; Attree, I.; Dessen, A.; Poignard, P.
10.1101/2024.10.19.619220 — microbiology — Posted on 2024-11-13
2893 Time-restricted feeding provides limited microglial immunometabolic improvements in diet-induced obese rats
Jiao, H.; Jermei, J.; Liang, X.; van der Zande, H. J. P.; Vrieling, F.; Rumanova, V. S.; Dorscheidt, M.; Correa-da-Silva, F.; Wang, A.; Foppen, E.; Arias, A. P.; Stenvers, D. J.; Liu, T.; Bonger, K.; Stienstra, R.; Zhi, Z.; Kalsbeek, A.; Yi, C.-X.
10.1101/2024.09.04.611250 — immunology — Posted on 2024-11-13
2894 Roles of the 5-HT1A receptor in zebrafish responses to potential threat and in sociality
de Sousa, L. V. X. B.; de Oliveira, L. N.; Costa, B. P. D.; Lima-Maximino, M.; Veloso, V.; Maximino, C.
10.1101/2024.04.17.588464 — neuroscience — Posted on 2024-11-13
2899 Why is there so much variability in crop multi-model studies?
Wallach, D.; Palosuo, T.; Mielenz, H.; Buis, S.; Thorburn, P.; Asseng, S.; Dumont, B.; Ferrise, R.; Gayler, S.; Ghahramani, A.; Harrison, M. T.; Hochman, Z.; Hoogenboom, G.; Huang, M.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Launay, M.; Lewan, E.; Liu, K.; Luo, Q.; Mequanint, F.; Nendel, C.; Padovan, G.; Olesen, J. E.; Pullens, J. W. M.; Qian, B.; Seserman, D.-M.; Shelia, V.; Souissi, A.; Specka, X.; Wang, J.; Weber, T. K. D.; Weihermuller, L.; Seidel, S.
10.1101/2023.02.03.526931 — plant biology — Posted on 2024-11-13
2900 Neuroinflammation in the dorsomedial striatum causes excessive goal-directed action control by disrupting homeostatic astrocyte function
Abiero, A. R.; Gladding, J. M.; Iredale, J.; Drury, H. R.; Manning, E. E.; Dayas, C. V.; Dhungana, A.; Ganesan, K.; Turner, K.; Becchi, S.; Kendig, M. D.; Nolan, C.; Balleine, B. W.; Castorina, A.; Cole, L.; Clemens, K.; Bradfield, L.
10.1101/2024.10.24.620154 — animal behavior and cognition — Posted on 2024-11-13
2903 The TCRs of pathogenic Th17 cells in arthritogenic mice are shifted toward a Treg-like repertoire
Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.
10.1101/2024.03.01.582868 — immunology — Posted on 2024-11-13
2905 Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy
Ivakhnenko, O. V.; Todrin, O. F.; Globa, V. Y.; Chyzh, M. O.; Kovalov, G. O.; Shevchenko, S. N.
10.1101/2024.10.19.619201 — biophysics — Posted on 2024-11-13
2908 Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification
Li, M. J.; Meyer, L. C.; Meier, N.; Witte, J.; Maldacker, M.; Seredynska, A.; Schueler, J.; Schilling, O.; Foell, M. C.
10.1101/2024.11.08.622662 — biochemistry — Posted on 2024-11-13
2910 A KCNC1 Variant Linked to Rett Syndrome Disrupts ER to Golgi Trafficking of Kv3.1 Channel
Maureira, D.; Rubilar, C.; Lopez, J.; Santander, P.; Moldenhauer, H.; Silva, I.; Cruz, P.; Riquelme, D.; Baeza, J.; Gonzalez, W.; Orio, P.; Servili, E.; Troncoso, M.; Leiva-Salcedo, E.; Cerda, O.
10.1101/2024.11.12.623225 — cell biology — Posted on 2024-11-13
2911 Overexpression of betaTrCP1 elicits cell death in cisplatin-induced senescent cells
Belmonte-Fernandez, A.; Herrero-Ruiz, J.; Limon-Mortes, M. C.; Saez, C.; Japon, M. A.; Mora-Santos, M.; Romero, F.
10.1101/2024.11.12.622981 — cell biology — Posted on 2024-11-13
2912 Semaphorin 4A maintains functional diversity of the hematopoietic stem cell pool
Toghani, D.; Gupte, S.; Zeng, S.; Mahammadov, E.; Crosse, E.; Seyedhassantehrani, N.; Burns, C.; Gravano, D.; Radtke, S.; Kiem, H.-P.; Rodriguez, S.; Carlesso, N.; Pradeep, A.; Georgiades, A.; Lucas, F.; Wilson, N. K.; Kinston, S. J.; Gottgens, B.; Zong, L.; Beerman, I.; Park, B.; Janssens, D.; Jones, D.; Toghani, A.; Nerlov, C.; Pietras, E. C.; Mesnieres, M.; Maes, C.; Kumanogoh, A.; Worzfeld, T.; Cheong, J.-G.; Josefowicz, S. Z.; Kharchenko, P.; Scadden, D.; Scialdone, A.; Spencer, J. A.; Silberstein, L.
10.1101/2024.11.12.622506 — cell biology — Posted on 2024-11-13
2914 Loss of TMEM55B modulates lipid metabolism through dysregulated lipophagy and mitochondrial function
Qin, Y.; Teker, S.; La Cunza, N.; Theusch, E.; Yang, N.; Venkatesan, L.; Su, J.; Krauss, R. M.; Lakkaraju, A.; Mattis, A. N.; Medina, M. W.
10.1101/2024.11.12.623285 — cell biology — Posted on 2024-11-13
2915 Targeted pre-conditioning and cell transplantation in the murine lower respiratory tract
Kohn, A.; Herriges, M. J.; Basak, P.; Ma, L.; Thapa, B. R.; Kotton, D. N.; Hawkins, F. J.
10.1101/2024.11.12.622518 — cell biology — Posted on 2024-11-13
2916 Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia
Nohara, T.; Kumamoto, J.; Mai, Y.; Shimano, M.; Kato, S.; Kitahata, H.; Nakamura, H.; Takashima, S.; Watanabe, M.; Nagayama, M.; Oikawa, T.; Ujiie, H.; Natsuga, K.
10.1101/2024.11.12.623158 — cell biology — Posted on 2024-11-13
2917 Lysosomes cell autonomously regulate myeloid cell states and immune responses
Tejwani, L.; Balak, C.; Skuja, L. L.; Tatarakis, D.; Rana, A.; Fitzgerald, G. A.; Ha, C.; de Melo, G. L.; Sun, E. W.; Heffner, C. M.; Simon, M. J.; Dugas, J. C.; Sarrafha, L.; Liang, E.; Sandmann, T.; Glass, C. K.; Di Paolo, G.
10.1101/2024.11.11.623074 — neuroscience — Posted on 2024-11-13
2920 Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells
Makela, A. V.; Tundo, A.; Liu, H. V.; Schneider, D.; Hermiston, T.; Khodakivskyi, P.; Goun, E.; Contag, C. H.
10.1101/2024.01.12.575071 — cancer biology — Posted on 2024-11-12
2923 Cost-effective DNA storage with DNA movable type
Wang, C.; Wei, D.; Wei, Z.; Yang, D.; Xing, J.; Wang, Y.; Wang, X.; Wang, P.; Ma, G.; Zhang, X.; Li, H.; Tang, C.; Hou, P.; Wang, J.; Gao, R.; Xie, G.; Li, C.; Ju, Y.; Wang, P.; Yue, L.; Zhao, Y.; Sheng, Y.; Xiao, J.; Niu, H.; Xu, S.; Yang, H.; Liu, D.; Duan, B.; Bu, D.; Tan, G.; Chen, F.
10.1101/2024.07.17.603163 — bioinformatics — Posted on 2024-11-12
2924 Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery
Zhuang, P.; Scott, B.; Gao, S.; Meng, W.-M.; Yin, R.; Nie, X.; Gaiaschi, L.; Lawler, S. E.; Lamfers, M. L.; Bei, F.; Cho, C.-F.
10.1101/2024.11.11.622979 — bioengineering — Posted on 2024-11-12
2925 Transposable element accumulation drives genome size increase in Hylesia metabus (Lepidoptera: Saturniidae), an urticating moth species from South America
Perrier, C.; Allio, R.; Legeai, F.; Gautier, M.; Beneluz, F.; Marande, W.; Theron, A.; Rodde, N.; Herrera, M.; Saune, L.; Parrinello, H.; McClure, M.; Arias, M.
10.1101/2024.07.11.602864 — genomics — Posted on 2024-11-12
2926 Structure of an Archaeal Ribosome with a Divergent Active Site
Nissley, A. J.; Shulgina, Y.; Kivimae, R. W.; Downing, B. E.; Penev, P. I.; Banfield, J. F.; Nayak, D. D.; Cate, J. H. D.
10.1101/2024.11.12.623245 — evolutionary biology — Posted on 2024-11-12
2928 Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along cochlear axis
Yan, M.; Zhang, P.; Wang, Y.; Wang, H.; Li, J.; Guo, X.; Zeng, X.; Feng, Z.; Gao, Y.; Deng, F.; Zhu, B.; Deng, D.; Ma, L.; Feng, Y.; Wu, H.-J.; Zhao, Y.; Li, J.
10.1101/2024.10.30.621022 — developmental biology — Posted on 2024-11-12
2929 Inpp5e Is Critical for Photoreceptor Outer Segment Maintenance
Gupta, M.; Lewis, T. R.; Stuck, M. W.; Spencer, W. J.; Klementieva, N. V.; Arshavsky, V. Y.; Pazour, G. J.
10.1101/2024.08.27.609873 — cell biology — Posted on 2024-11-12
2931 Lipid-driven SRC self-association modulates its transformation capacity
Mohammad Jabeen, I.-L.; Giannotti, M.; Fourgous, E.; Boublik, Y.; Fernandez, A.; Le Roux, A.-L.; Sirvent, A.; Taules, M.; roche, s.; Pons, M.
10.1101/2024.11.12.623151 — molecular biology — Posted on 2024-11-12
2933 Meningeal Regulatory T cell-derived enkephalin gates nociception
Midavaine, E.; Moraes, B. C.; Benitez, J.; Rodriguez, S. R.; Braz, J. M.; Kochhar, N. P.; Eckalbar, W. L.; Domingos, A. I.; Pintar, J. E.; Basbaum, A. I.; Kashem, S. W.
10.1101/2024.05.11.593442 — immunology — Posted on 2024-11-12
2934 Systemic inflammation and lymphocyte activation precede rheumatoid arthritis
He, Z.; Glass, M. C.; Venkatesan, P.; Feser, M. L.; Lazaro, L.; Okada, L. Y.; Tran, N. T. T.; He, Y. D.; Rachid Zaim, S.; Bennett, C. E.; Ravisankar, P.; Dornisch, E. M.; Arishi, N. A.; Asamoah, A. G.; Barzideh, S.; Becker, L. A.; Bemis, E. A.; Buckner, J. H.; Collora, C. E.; Criley, M. A. L.; Demoruelle, M. K.; Fleischer, C. L.; Garber, J.; Genge, P. C.; Gong, Q.; Graybuck, L. T.; Gustafson, C. E.; Hattel, B. C.; Hernandez, V.; Heubeck, A. T.; Kawelo, E. K.; Krishnan, U.; Kuan, E. L.; Kuhn, K. A.; LaFrance, C. M.; Lee, K. J.; Li, R.; Lord, C.; Mettey, R. R.; Moss, L.; Musgrove, B.; Nguyen, K.
10.1101/2024.10.25.620344 — immunology — Posted on 2024-11-12
2935 Model Based Inference of Synaptic Plasticity Rules
Mehta, Y.; Tyulmankov, D.; Rajagopalan, A. E.; Turner, G. C.; Fitzgerald, J. E.; Funke, J.
10.1101/2023.12.11.571103 — neuroscience — Posted on 2024-11-12
2936 Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships
Brusman, L. E.; Sadino, J. M.; Fultz, A. C.; Kelberman, M. A.; Dowell, R. D.; Allen, M. A.; Donaldson, Z. R.
10.1101/2024.03.27.587112 — neuroscience — Posted on 2024-11-12
2937 Birth order specified recruitment of motor circuits during spontaneous neural activity in zebrafish embryo
Abi Younes, M.; Rima, M.; Coutanceau, J.-p.; Peysson, N.; Hoseinkhani, F.; Rodrigues, E.; Bullier, E.; Legendre, P.; Mangin, J.-M.; Hong, E.
10.1101/2024.08.27.609675 — neuroscience — Posted on 2024-11-12
2939 Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness
Fotiadis, P.; McKinstry-Wu, A. R.; Weinstein, S. M.; Cook, P. A.; Elliott, M.; Cieslak, M.; Duda, J. T.; Satterthwaite, T. D.; Shinohara, R. T.; Proekt, A.; Kelz, M. B.; Detre, J. A.; Bassett, D. S.
10.1101/2024.10.04.616650 — neuroscience — Posted on 2024-11-12
2941 Outer hair cells stir cochlear fluids
Lee, C.; Shokrian, M.; Henry, K. S.; Carney, L.; Holt, J. C.; Nam, J.-H.
10.1101/2024.08.07.607009 — neuroscience — Posted on 2024-11-12
2943 Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease
Janssens, J. V.; Raaijmakers, A. J. A.; Koutsifeli, P.; Weeks, K. L.; Bell, J. R.; Van Eyk, J. E.; Curl, C. L.; Mellor, K. M.; Delbridge, L. M. D.
10.1101/2024.02.21.581448 — physiology — Posted on 2024-11-12
2944 Surface remodeling and inversion of cell-matrix interactions underlies community recognition and dispersal in Vibrio cholerae biofilms
Moreau, A. P.; Nguyen, D. T.; Hinbest, A.; Zamora, A.; Weerasekera, R.; Matej, K.; Zhou, X.; Sanchez, S.; Rodriguez-Brenes, I. A.; Tai, J.-S. B.; Nadell, C. D.; Ng, W.-L.; Gordon, V. D.; Komarova, N. L.; Olson, R.; Li, Y.; Yan, J.
10.1101/2024.11.11.623042 — biophysics — Posted on 2024-11-12
2945 scEGOT: Single-cell trajectory inference framework based on entropic Gaussian mixture optimal transport
Yachimura, T.; Wang, H.; Imoto, Y.; Yoshida, M.; Tasaki, S.; Kojima, Y.; Yabuta, Y.; Saitou, M.; Hiraoka, Y.
10.1101/2023.09.11.557102 — bioinformatics — Posted on 2024-11-12
2949 fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans
Tuckowski, A. M.; Beydoun, S.; Kitto, E. S.; Bhat, A.; Howington, M. B.; Sridhar, A.; Bhandari, M.; Chambers, K.; Leiser, S. F.
10.1101/2024.05.17.594584 — genetics — Posted on 2024-11-12
2950 Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus
Uttley, K.; Jüllig, H. J.; De Angelis, C.; Auer, J. M.; Ozga, E.; Bengani, H.; Long, H. K.
10.1101/2024.09.24.614243 — genetics — Posted on 2024-11-12
2951 An old inversion polymorphism involving giant mobile elements in an invasive fungal pathogen
Hartmann, F. E.; Rodriguez de la Vega, R. C.; Demene, A.; Badet, T.; Vernadet, J.-P.; Rougemont, Q.; Labat, A.; Snirc, A.; Stauber, L.; Croll, D.; Prospero, S.; Dutech, C.; Giraud, T.
10.1101/2024.03.29.587348 — evolutionary biology — Posted on 2024-11-12
2953 Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease
Albarran-Juarez, J.; Markov, A.; Jensen, A. L.; Moller, P. L.; Uryga, A. K.; Djordjevic, D.; Hansen, J.; Jensen, L. F.; Sharysh, D.; Pyke, C.; Moreno, J.; Borghetti, G.; Bachmann, J.; Herum, K.; Roge, L. M.; Traylor, M.; Nyberg, M.; Nyegaard, M.; Bentzon, J. F.
10.1101/2024.11.11.623011 — cell biology — Posted on 2024-11-12
2956 Investigating the genetic relationship of Trichosporon asahii isolates using a newly developed microsatellite typing assay
Francisco, E. C.; Fernandez, N. B.; Carbia, M.; Dieleman, C.; Bostanaru-Iliescu, A.-C.; Houbraken, J.; Colombo, A. L.; Hagen, F.
10.1101/2024.11.12.623230 — molecular biology — Posted on 2024-11-12
2958 Metabolic insights into microbially induced calcite formation by Bacillaceae for application in bio-based construction materials
Michael, S.; Hamley-Bennett, C.; Reeksting, B. J.; Bagga, M.; Hellmann, L.; Hoffmann, T. D.; Kraemer, C.; Ofiteru, I. D.; Paine, K.; Gebhard, S.
10.1101/2024.11.12.623140 — microbiology — Posted on 2024-11-12
2959 Influenza A virus transcription generates capped cRNAs that activate RIG-I
Elshina, E.; Pitre, E.; Mendes, M.; Schweibenz, B.; French, H.; Park, J. W.; Wang, W.; Marcotrigiano, J.; Russell, A. B.; te Velthuis, A. J. W.
10.1101/2024.11.12.623191 — microbiology — Posted on 2024-11-12
2960 Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms
Bunbury, F.; Rivas, C.; Calatrava, V.; Malkovskiy, A.; Joubert, L.-M.; Parvate, A.; Evans, J. E.; Grossman, A. R.; Bhaya, D.
10.1101/2024.07.24.605005 — microbiology — Posted on 2024-11-12
2962 Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer's disease
Terstege, D. J.; Ren, Y.; Ahn, B. Y.; Seo, H.; Alzheimer's Disease Neuroimaging Initiative, ; Galea, L.; Sargin, D.; Epp, J. R.
10.1101/2023.06.22.546142 — neuroscience — Posted on 2024-11-12
2964 Correction of RBFOX1 deficit rescues Huntington's disease mis-splicing and pathology
Lozano-Munoz, D.; Elorza, A.; Mayor-Fidalgo, L.; Santos-Galindo, M.; Lucas-Santamaria, M.; Parras, A.; Lucas, J. J.
10.1101/2024.11.06.622223 — neuroscience — Posted on 2024-11-12
2966 Corticothalamic modelling of sleep neurophysiology with applications to mobile EEG
Morshedzadeh, T.; Kadak, K.; Bastiaens, S. P.; Oveisi, M. P.; Momi, D.; Wang, Z.; Harita, S.; Abou Jaude, M.; Aimone, C. A.; Mann, S.; Hill, S. L.; Griffiths, J. D.
10.1101/2024.02.28.582655 — neuroscience — Posted on 2024-11-12
2969 TLL1 knockdown attenuates prostate cancer progression by enhancing antitumor immunity
hao, j.; He, J.; Hu, H.; Wu, X.; Zhu, Z.; Zhao, X.; Li, L.; Ruan, Y.; Yang, J.; Fu, M.; Zhang, K.; Gao, P.; Dong, X.
10.1101/2024.11.11.623110 — cancer biology — Posted on 2024-11-12
2970 Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state
Rominger, M. C.; Gupta, S.; Moorthi, S.; McSharry, M.; Kamlapurkar, S.; O'Brien, S.; Waldum, A.; Lo, A.; Duke, F.; Lowe, A.; Cromwell, E.; Glabman, R.; Koehne, A.; Berger, A.
10.1101/2024.11.11.623044 — cancer biology — Posted on 2024-11-12
2971 Development of a pipeline to evaluate YAP-TEAD inhibitor potential - direct TEAD inhibition represses cancerous growth in a NF2-mutant model of mesothelioma
Cunningham, R.; Jia, S.; Purohit, K.; Fairley, M. N.; Lin, Y.; Hui, N. S.; Graham, R. E.; Rossi, A. G.; Cholewa-Waclaw, J.; Carragher, N. O.; Hansen, C. G.
10.1101/2024.11.12.622964 — cancer biology — Posted on 2024-11-12
2972 Targeting synthetic lethality between non-homologous end joining and radiation in very high-risk SHH medulloblastoma
DeCarlo, A.; Macleod, G.; Fernandes da Silva, C.; Shen, L.; Aragao, L.; Sie, M.; Termini, D.; Magee, J.; Gudenas, B.; Sukumaran, S.; Charron, F.; Marcellus, R.; Al-Awar, R.; Aman, A.; Tabori, U.; Nor, C.; Northcott, P.; Dirks, P. B.; Angers, S.; Ramaswamy, V.
10.1101/2024.11.11.622104 — cancer biology — Posted on 2024-11-12
2973 Detection of Unlabeled Micro- and Nanoplastics in Unstained Tissue with Optical Photothermal Infrared Spectroscopy
Duswald, K.; Pichler, V.; Kopatz, V.; Limberger, T.; Karl, V.; Wimberger, D.; Zimmerleiter, R.; Wadsak, W.; Hettich, M.; Kenner, L.; Brandstetter, M.
10.1101/2024.11.11.622943 — biophysics — Posted on 2024-11-12
2974 Stress Changes the Bacterial Biomolecular Condensate Material State and Shifts Function from mRNA Decay to Storage
Ortiz-Rodrlguez, L. A.; Yassine, H.; Nandana, V.; Azaldegui, C. A.; Cheng, J.; Schrader, J. M.; Biteen, J. S.
10.1101/2024.11.12.623272 — biophysics — Posted on 2024-11-12
2977 Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking
Thawani, A.; Rodriguez-Vargas, A.; Treeck, B. V.; Hassan, N. T.; Adelson, D. L.; Nogales, E.; Collins, K.
10.1101/2024.11.11.623112 — biochemistry — Posted on 2024-11-12
2978 Molecular determinants of protein pathogenicity at the single-aggregate level
Urbanek, A.; Garland, E. F.; Prescott, E. E.; King, M. C.; Olerinyova, A.; Wareing, H. E.; Georgieva, N.; Bradshaw, E. L.; Tzokov, S. B.; Knight, A.; Tartakovskii, A. I.; Malm, T.; Highley, J. R.; De, S.
10.1101/2024.11.12.623279 — biochemistry — Posted on 2024-11-12
2979 Fibril fragmentation generates diversity in seed population
Pedrola, J. A.; Todorovska, M.; Singh, S.; Friedler, A.; Rudiger, S.
10.1101/2024.11.12.623277 — biochemistry — Posted on 2024-11-12
2981 Identification of methylation-sensitive human transcription factors using meSMiLE-seq
Gralak, A. J.; Faltejskova, K.; Yang, A. W. H.; Steiner, C.; Russeil, J.; Grenningloh, N.; Inukai, S.; Demir, M.; Dainese, R.; Owen, C.; Pankevich, E.; Codebook/GRECO-BIT Consortium, ; Hughes, T. R.; Kulakovskiy, I. V.; Kribelbauer-Swietek, J. F.; van Mierlo, G.; Deplancke, B.
10.1101/2024.11.11.619598 — genomics — Posted on 2024-11-12
2982 Perspectives on Codebook: sequence specificity of uncharacterized human transcription factors
Jolma, A.; Laverty, K. U.; Fathi, A.; Yang, A. W.; Yellan, I.; Vorontsov, I. E.; Inukai, S.; Kribelbauer, J. F.; Gralak, A. J.; Razavi, R.; Albu, M.; Brechalov, A.; Patel, Z. M.; Nozdrin, V.; Meshcheryakov, G.; Kozin, I.; Abramov, S.; Boytsov, A.; The Codebook Consortium, ; Fornes, O.; Makeev, V. J.; Grau, J.; Grosse, I.; Bucher, P.; Deplancke, B.; Kulakovskiy, I. V.; Hughes, T. R.
10.1101/2024.11.11.622097 — genomics — Posted on 2024-11-12
2983 Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
Denoeud, F.; Godfroy, O.; Cruaud, C.; Heesch, S.; Nehr, Z.; Tadrent, N.; Couloux, A.; Brillet-Gueguen, L.; Delage, L.; Mckeown, D.; Motomura, T.; Sussfeld, D.; Fan, X.; Mazeas, L.; Terrapon, N.; Barrera-Redondo, J.; Petroll, R.; Reynes, L.; Choi, S.-W.; Jo, J.; Uthanumallian, K.; Bogaert, K.; Duc, C.; Ratchinski, P.; Lipinska, A.; Noel, B.; Murphy, E. A.; Lohr, M.; Khatei, A.; Hamon-Giraud, P.; Vieira, C.; Akerfors, S. S.; Akita, S.; Avia, K.; Badis, Y.; Barbeyron, T.; Belcour, A.; Berrabah, W.; Blanquart, S.; Bouguerba, A.; Bringloe, T. T.; Cattolico, R. A.; Cormier, A.; Cruz de Carvalho, M.
10.1101/2024.02.19.579948 — genomics — Posted on 2024-11-12
2984 Chromatin architecture mapping by multiplex proximity tagging
Delamarre, A.; Bailey, B.; Yavid, J.; Koche, R.; Mohibullah, N.; Whitehouse, I.
10.1101/2024.11.12.623258 — molecular biology — Posted on 2024-11-12
2985 Quantification of subcellular RNA localization through direct detection of RNA oxidation
Lo, H.-Y. G.; Goering, R.; Kocere, A.; Lo, J.; Pockalny, M.; White, L. K.; Ramirez, H.; Martinez, A.; Jacobson, S.; Spitale, R. C.; Pearson, C. G.; Resendiz, M. J.; Mosimann, C.; Taliaferro, M.
10.1101/2024.11.12.623278 — molecular biology — Posted on 2024-11-12
2987 Salinity impacted microbial carbonate precipitation mechanisms of modern microbialites in peritidal zone
Hsieh, Y. E.; Yang, S.-Y.; Liu, S.-L.; Wang, S.-W.; Wang, W.-L.; Tang, S.-L.; Yang, S.-H.
10.1101/2024.11.11.623098 — microbiology — Posted on 2024-11-12
2988 A conserved in vivo burn wound infection model for diverse pathogenic fungi.
Mercado-Soto, N.; Horn, A.; Keller, N. P.; Huttenlocher, A.; Wagner, A. S.
10.1101/2024.11.12.623264 — microbiology — Posted on 2024-11-12
2989 Impact of oral Chlamydia Vaccination on Host Gut Microbiome and Metabolites Composition
Huang, Y.; Wan, J.; Shu, C.; Zhang, Q.; Zhou, Z.; Sun, X.; Wang, L.; Zhang, T.; Tian, Q.
10.1101/2024.11.11.623094 — microbiology — Posted on 2024-11-12
2990 Resource landscape shapes the composition and stability of the human vaginal microbiota
Kamiya, T.; Sofonea, M. T.; France, M.; Tessandier, N.; Bravo, I. G.; Murall, C. L.; Ravel, J.; Alizon, S.
10.1101/2024.11.12.622464 — microbiology — Posted on 2024-11-12
2991 Complete genomes of DNA viruses in faecal samples from small terrestrial mammals in Spain
Buigues, J.; Vinals, A.; Martinez-Recio, R.; Monros, J.; Sanjuan, R.; Cuevas, J.
10.1101/2024.11.12.623162 — microbiology — Posted on 2024-11-12
2992 Sigma factors as potential targets to enhance recombinant protein expression
Pohlen, L.; Garcia, E.; Martinez, L. M.; Flores, N.; Buechs, J.; Gosset, G.; LARA, A. R.
10.1101/2024.11.12.623148 — microbiology — Posted on 2024-11-12
2994 Proteomic characterization of Mycobacterium tuberculosis subjected to carbon starvation
Devlin, K. L.; Leach, D. T.; Stratton, K. G.; Lamichhane, G.; Lin, V.; Beatty, K. E.
10.1101/2024.11.12.623260 — microbiology — Posted on 2024-11-12
2996 Prefrontal cortex encodes behavior states decoupled from movement
Rautio, I. V.; Nevjen, F.; Hem, I. G.; Dunn, B. A.; Whitlock, J. R.
10.1101/2024.11.11.623038 — neuroscience — Posted on 2024-11-12
2998 Spotiphy enables single-cell spatial whole transcriptomics across the entire section
Yang, J.; Zheng, Z.; Jiao, Y.; Yu, K.; Bhatara, S.; Yang, X.; Natarajan, S.; Zhang, J.; Easton, J.; Yan, K.-K.; Peng, J.; Liu, K.; Yu, J.
10.1101/2024.11.11.623040 — systems biology — Posted on 2024-11-12
3000 Differential beta and gamma activity modulation during unimanual and bimanual motor learning
Wu, M.; Schoenfeld, M. J.; Lindersson, C.; Braeutigam, S.; Zich, C.; Stagg, C. J.
10.1101/2024.11.11.623009 — physiology — Posted on 2024-11-12
3002 Spatial Transcriptomics Reveals Inflammation and Trans-differentiation States of Acute Myeloid Leukemia in Extramedullary and Medullary Tissues
Dasdemir, E.; Veletic, I.; Ly, C. P.; Quesada, A. E.; Pacheco, C. D.; Jelloul, F. Z.; Borges, P.; Basu, S.; Jindal, S.; Wang, Z.; Lazar, A.; Wani, K. M.; Antunes, D. A.; Reville, P. K.; Gunaratne, P. H.; Tower, R. J.; Sharma, P.; Abbas, H. A.
10.1101/2024.11.11.622999 — cancer biology — Posted on 2024-11-12
3003 The Impact of Charge Regulation and Ionic Intranuclear Environment on the Nucleosome Core Particle
Nap, R. J.; Gonzalez, P. C.; Coraor, A. E.; Virk, R. K. A.; de Pablo, J. J.; Backman, V.; Szleifer, I.
10.1101/2024.11.11.623012 — biophysics — Posted on 2024-11-12
3006 Non-destructive transcriptomics via vesicular export
Armbrust, N.; Geilenkeuser, J.; Grosshauser, M.; Stroppel, L.; Schmidt, S.; Panne, T.; Steinmassl, E.; Widenmeyer, F.; Warsing, N.; Berezin, O.; Sabry, M.; Sultanbai, A.; Santl, T.; Theis, F.; Gagneur, J.; Truong, D.-J. J.; Westmeyer, G. G.
10.1101/2024.11.11.622832 — bioengineering — Posted on 2024-11-12
3007 LOL-EVE: Predicting Promoter VariantEffects from Evolutionary Sequences
Shearer, C.; Teufel, F.; Orenbuch, R.; Ritter, D.; Spinner, A.; Xie, E.; Frazer, J.; Dias, M.; Notin, P.; Marks, D.
10.1101/2024.11.11.623015 — genomics — Posted on 2024-11-12
3008 Response splicing QTLs in primary human chondrocytes identifies putative osteoarthritis risk genes
Byun, S.; Coryell, P.; Kramer, N.; D'Costa, S.; Thulson, E.; Shine, J.; Parkus, S.; Chubinskaya, S.; Loeser, R.; Diekman, B. O.; Phanstiel, D. H.
10.1101/2024.11.11.622754 — genetics — Posted on 2024-11-12
3010 Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases
Chernigovskaya, M.; Le Quy, K.; Stensland, M.; Singh, S.; Nelson, R.; Yilmaz, M.; Kalogeropoulos, K.; Sinitcyn, P.; Patel, A.; Castellana, N.; Bonissone, S.; Foss, S.; Andersen, J. T.; Sandve, G. K.; Jenkins, T. P.; Noble, W. S.; Nyman, T. A.; Snapkow, I.; Greiff, V.
10.1101/2024.11.11.622451 — immunology — Posted on 2024-11-12
3011 Opposing Regulation of TNF Responses and IL-1b+ Macrophages by PGE2-cAMP and IFN-g Signaling
Sokhi, U. K.; Mishra, B.; Yuan, R.; Chinenov, Y.; Singaraju, A.; Chan, K. K.; Bass, A.; Donlin, L.; Ivashkiv, L. B.
10.1101/2024.11.11.623039 — immunology — Posted on 2024-11-12
3012 The Interaction Of Diet-Induced Obesity And Chronic Stress In A Mouse Model Of Menopause
Knox, N.; Yasrebi, A.; Caramico, D.; Wiersielis, K.; Samuels, B. A.; Roepke, T. A.
10.1101/2024.11.11.622997 — neuroscience — Posted on 2024-11-12
3014 Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala
Campbell, J. M.; Cowan, R. L.; Wahlstrom, K. L.; Hollearn, M. K.; Jensen, D.; Davis, T.; Rahimpour, S.; Shofty, B.; Arain, A.; Rolston, J. D.; Hamann, S.; Wang, S.; Eisenman, L. N.; Swift, J.; Xie, T.; Brunner, P.; Manns, J. R.; Inman, C. S.; Smith, E. H.; Willie, J. T.
10.1101/2024.11.11.622161 — neuroscience — Posted on 2024-11-12
3015 Targeting the tomato fruit cuticle by gene overexpression and editing with the fruit epidermis-preferential nsLTP promoter
Alonso, M.; Paulsen, E.; Pedemay, S.; D'Orlando, A.; Lahaye, M.; Marion, D.; Bakan, B.; Rothan, C.; Petit, J.
10.1101/2024.11.11.622963 — plant biology — Posted on 2024-11-12
3017 Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery
Cho, C.-F.; Zhuang, P.; Scott, B.; Gao, S.; Meng, W.-M.; Yin, R.; Nie, X.; Gaiaschi, L.; Lawler, S. E.; Lamfers, M. L.; Bei, F.
10.1101/2024.11.11.622979 — bioengineering — Posted on 2024-11-12
3020 Connectivity and population structure in a marginal sea - a review
Henriksson, S.; Jorde, P. E.; Berkstrom, C.; Sovik, G.; De Wit, P. R.; Knutsen, H.; Moland, E.; Andre, C.; Jahnke, M.
10.1101/2024.11.11.622907 — ecology — Posted on 2024-11-12
3022 Modeling neuron-astrocyte interactions in neural networks using distributed simulation
Jiang, H.-J.; Acimovic, J.; Manninen, T.; Ahokainen, I.; Stapmanns, J.; Lehtimaki, M.; Diesmann, M.; van Albada, S. J.; Plesser, H. E.; Linne, M.-L.
10.1101/2024.11.11.622953 — neuroscience — Posted on 2024-11-12
3023 CETP expression in females increases body metabolism under both cold exposure and thermoneutrality contributing to a leaner phenotype
Castelli, J. Z.; Raposo, H. F.; Navarro, C. D. C.; Lazaro, C. M.; Sartori, M. R.; Costa, A. P. D.; Nogueira, P. A. S.; Velloso, L. A.; Vercesi, A. E.; Oliveira, H. C. F.
10.1101/2024.11.11.623058 — physiology — Posted on 2024-11-12
3026 Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors
Vorontsov, I. E.; Kozin, I.; Abramov, S.; Boytsov, A.; Jolma, A.; Albu, M.; Ambrosini, G.; Faltejskova, K.; Gralak, A. J.; Gryzunov, N.; Inukai, S.; Kolmykov, S.; Kravchenko, P.; Kribelbauer-Swietek, J. F.; Laverty, K. U.; Nozdrin, V.; Patel, Z. M.; Penzar, D.; Plescher, M.-L.; Pour, S. E.; Razavi, R.; Yang, A. W. H.; Yevshin, I.; Zinkevich, A.; Weirauch, M. T.; Bucher, P.; Deplancke, B.; Fornes, O.; Grau, J.; Grosse, I.; Kolpakov, F. A.; Codebook/GRECO-BIT Consortium, ; Makeev, V. J.; Hughes, T. R.; Kulakovskiy, I. V.
10.1101/2024.11.11.619379 — bioinformatics — Posted on 2024-11-12
3027 Genomic characterization of a persistent, azole-resistant C. parapsilosis strain responsible for a hospital outbreak during the first COVID-19 wave
Vumbaca, M.; Batisti Biffignandi, G.; Cavanna, C.; Belllinzona, G.; Corbella, M.; Cambieri, P.; Rhodes, J.; Corander, J.; Baldanti, F.; Sassera, D.
10.1101/2024.11.11.622614 — genomics — Posted on 2024-11-12
3028 Monandrous flies do remate: plastic and evolutionary consequences of heat exposure on mating behaviour and fertility in Drosophila subobscura
Grandela, A.; Antunes, M. A.; Santos, M. A.; Quina, A. S.; Costa, I. R.; Borges, G.; Matos, M.; Rodrigues, L. R.; Simoes, P.
10.1101/2024.11.12.623111 — evolutionary biology — Posted on 2024-11-12
3030 Maternal exercise alters placental proteome in an exercise mode-specific manner
Jevtovic, F.; Wisseman, B.; Jahan, F.; Claiborne, A.; Collier, D. N.; DeVente, J. E.; Mouro, S.; Zeczycki, T. N.; Goodyear, L. J.; May, L. E.
10.1101/2024.11.11.623023 — developmental biology — Posted on 2024-11-12
3032 Vaccine-induced and hybrid immunity against SARS-CoV-2 variants of concern in two cohorts in Queensland, Australia (2021-2022).
Parry, R. H.; Shang, Y. H.; Sng, J. D. J.; McMillan, C. L. D.; Modhiran, N.; Amarilla, A. A.; Isaacs, A.; Liang, B.; Muller, D. A.; Rawle, D. J.; Suhrbier, A.; Anderson, S.; Kelly, S.; Watterson, D.; Burr, L.; Khromykh, A.
10.1101/2024.11.11.623100 — microbiology — Posted on 2024-11-12
3033 ConvexGating infers gating strategies from clusters in single cell cytometry data
Friedrich, V. D.; Mai, K.; Hofer, T. P.; Noessner, E.; Bonaguro, L.; Hartmann, C. L.; Frolov, A.; Carraro, C.; Hamada, D.; Hadaddzadeh-Shakiba, M.; Scholz, M.; Theis, F. J.; Beyer, M. D.; Schultze, J. L.; Buttner, M.
10.1101/2024.11.11.623019 — immunology — Posted on 2024-11-12
3035 Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and next generation RNA sequencing
Pesti, I.; Varga, V.; Qorri, E.; Frank, R.; Kata, D.; Vinga, K.; Szarvas, P. A.; Menyhart, A.; Gulya, K.; Bari, F.; Farkas, E.
10.1101/2024.11.11.623031 — neuroscience — Posted on 2024-11-12
3037 Latent encoding of movement in primary visual cortex
Cosnier-Horeau, C.; Germaine, H.; Choi, I.; Van Hooser, S.; Ribot, J.; Touboul, J. D.
10.1101/2024.11.11.623057 — neuroscience — Posted on 2024-11-12
3039 Master regulators governing protein abundance across ten human cancer types
Wang, Z.; Wojciechowicz, M.; Rosen, J.; Elmas, A.; Song, W.-M.; Liu, Y.; Huang, K.-l.
10.1101/2024.11.11.619147 — systems biology — Posted on 2024-11-12
3040 System-level characterization of engineered and evolved formatotrophic E. coli strains
Yilmaz, S.; Kanis, B.; Hogers, R.; Benito-Vaquerizo, S.; Kahnt, J.; Glatter, T.; Dronsella, B.; Erb, T. J.; Suarez-Diez, M.; Claassens, N. J.
10.1101/2024.11.11.622960 — synthetic biology — Posted on 2024-11-12
3042 Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis
Drucker, M.; Lee, D.; Zhang, X.; Kain, B.; Bowman, M.; Nicolet, D.; Wang, Z.; Stone, R. M.; Mrozek, K.; Carroll, A. J.; Starczynowski, D. T.; Levine, R. L.; Byrd, J. C.; Eisfeld, A.-K.; Salomonis, N.; Grimes, L.; Bowman, R. L.; Miles, L. A.
10.1101/2024.11.11.623033 — cancer biology — Posted on 2024-11-12
3047 An integrative approach to prioritize candidate causal genes for complex traits in cattle
Ghoreishifar, M.; Macleod, I. M.; Chamberlain, A. J.; Liu, Z.; Lopdell, T. J.; Littlejohn, M. D.; Xiang, R.; Pryce, J. E.; Goddard, M. E.
10.1101/2024.11.11.622912 — genomics — Posted on 2024-11-12
3048 Extensive binding of uncharacterized human transcription factors to genomic dark matter
Razavi, R.; Fathi, A.; Yellan, I.; Brechalov, A.; Laverty, K. U.; Jolma, A.; Hernandez-Corchado, A.; Zheng, H.; Yang, A. W.; Albu, M.; Barazandeh, M.; Hu, C.; Vorontsov, I.; Patel, Z. M.; The Codebook Consortium, ; Kulakovskiy, I. V.; Bucher, P.; Morris, Q.; Najafabadi, H. S.; Hughes, T. R.
10.1101/2024.11.11.622123 — genomics — Posted on 2024-11-12
3049 GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors
Jolma, A.; Hernandez-Corchado, A.; Yang, A. W.; Fathi, A.; Laverty, K. U.; Brechalov, A.; Razavi, R.; Zheng, H.; The Codebook Consortium, ; Kulakovskiy, I. V.; Najafabadi, H. S.; Hughes, T. R.
10.1101/2024.11.11.618478 — genomics — Posted on 2024-11-12
3051 Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs
Bucao, C. F.; Aletti, C.; Moretti, S.; Thompson, A. W.; Racicot, B. L.; Wilson, C. A.; Bobe, J.; Braasch, I.; Guigen, Y.; Postlethwait, J. H.; Robinson-Rechavi, M.
10.1101/2024.11.11.623020 — evolutionary biology — Posted on 2024-11-12
3053 Spectrum of gamma-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes
Gutierrez Fernandez, S.; Gan Oria, C.; Annaert, W.; Ringman, J. M.; Fox, N. C.; Ryan, N. S.; Chavez-Gutierrez, L.
10.1101/2024.11.11.622936 — neuroscience — Posted on 2024-11-12
3056 Inhibition of serine and arginine-rich splicing factor 3 induces epidermal differentiation and decreases cutaneous squamous cell carcinoma risk
Donohue, I. M.; He, H.; Nguyen, A.; Hui, G.; Muralidharan, J.; Pike, W. C.; Jackson, M. L.; Ko, C.; Srivastava, A.; Lee, C. S.
10.1101/2024.11.07.622551 — cancer biology — Posted on 2024-11-12
3061 A systematic and meta-analytic review of non-verbal auditory memory in the brain
Campo, F. F.; Carlomagno, F.; Yilmaz, B.; Quaranta, L.; Carraturo, G.; Rivolta, D.; Brattico, E.
10.1101/2024.11.11.622965 — neuroscience — Posted on 2024-11-12
3063 Signals in the Cells: Multimodal and Contextualized Machine Learning Foundations for Therapeutics
Velez-Arce, A.; Lin, X.; Li, M.; Huang, K.; Gao, W.; Fu, T.; Pentelute, B. L.; Kellis, M.; Zitnik, M.
10.1101/2024.06.12.598655 — bioinformatics — Posted on 2024-11-12
3065 The protease interpain A of Prevotella intermedia promotes human OSCC cells proliferation and migration
Chang, S.-M.; Huang, I.-H.; Ciou, Y.-J.; Wang, W.-R.; Wu, N.-H.; Chuu, C.-P.; Hsiao, J.-R.; Chang, J. S.; Chang, J.-Y.; Chen, J.-W.
10.1101/2024.10.20.619282 — cancer biology — Posted on 2024-11-12
3067 Preliminary report on the molecular epidemiology of mpox, South Africa 2024
Featherston, J.; Grobbelaar, A.; Glass, A.; Goedhals, D.; Hoek, K.; Maritz, J.; Govender, K.; Govender, N.; Ismail, A.; le Roux, C.; Marshall, T.; Morobadi, D.; Moodley, M.; Moolla, N.; Mtshali, S.; Msimang, V.; Vardas, E.; Weyer, J.
10.1101/2024.11.07.622575 — microbiology — Posted on 2024-11-12
3071 Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia
Ardaya, M.; Tiveron, M.-C.; Cremer, H.; Dehay, B.; Perez-Cerda, F.; Matute, C.; Soria, F. N.; Cavaliere, F.
10.1101/2023.12.30.573719 — neuroscience — Posted on 2024-11-12
3073 Pancreatic cancer cells exchange ribosomes through tunneling nanotubes
Martinkova, S.; Jansova, D.; Vorel, J.; Lamacova, L. J.; Daniel, P.; Hudec, M.; Bodo, M.; Hajer, J.; Susor, A.; Trnka, J.
10.1101/2024.06.06.597772 — cancer biology — Posted on 2024-11-12
3074 Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer
Seo, Y.; Zhang, S.; Jang, J.; Ko, K.-P.; Kim, K.-B.; Huang, Y.; Kim, D.-W.; Kim, B.; Zou, G.; Zhang, J.; Jun, S.; Chu, W.; Kirk, N. A.; Hwang, Y. E.; Ban, Y. H.; Dhar, S. S.; Chan, J. M.; Lee, M.; Rudin, C. M.; Park, K.-S.; Park, J.-I.
10.1101/2023.02.15.528365 — cancer biology — Posted on 2024-11-12
3076 scLong: A Billion-Parameter Foundation Model for Capturing Long-Range Gene Context in Single-Cell Transcriptomics
Bai, D.; Mo, S.; Zhang, R.; Luo, Y.; Gao, J.; Yang, J. P.; Wu, Q.; Singh, D.; Rahmani, H.; Amariuta, T.; Grotjahn, D.; Zhong, S.; Lewis, N.; Wang, W.; Ideker, T.; Xie, P.; Xing, E.
10.1101/2024.11.09.622759 — bioinformatics — Posted on 2024-11-12
3077 The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition
Kavaklioglu, G.; Podhornik, A.; Vcelkova, T.; Marjanovic, J.; Beck, M. A.; Phan-Canh, T.; Mair, T.; Miccolo, C.; Drino, A.; Doni, M.; Egger, G.; Chiocca, S.; Modic, M.; Seiser, C.
10.1101/2024.02.01.577722 — genetics — Posted on 2024-11-12
3078 A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
Bacot, T.; Haberkorn, C.; Guilliet, J.; Cattel, J.; Kefi, M.; Nadalin, L.; Filee, J.; Boyer, F.; Gaude, T.; Laporte, F.; Tutagata, J.; Vontas, J.; Dusfour, I.; Bonneville, J.-M.; David, J.-P.
10.1101/2024.04.03.587871 — evolutionary biology — Posted on 2024-11-12
3083 CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance
Kheir, E.; Libergoli, M.; Metti, S.; Jensen, J. B.; Wang, J.; Jessen, N.; Florio, F.; Murganti, F.; Di Savino, S.; Belicchi, M.; Villa, C.; Vissing, K.; Verma, M.; Giordani, L.; Bonaldo, P.; Torrente, Y.; Farup, J.; Biressi, S.
10.1101/2024.10.25.619970 — cell biology — Posted on 2024-11-12
3086 Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles
Zheng, X.; Yu, S.; Zhou, Y.; Yu, K.; Gao, Y.; Chen, M.; Duan, D.; Li, Y.; Cui, X.; Mou, J.; Yang, Y.; Wang, X.; Chen, M.; Jiu, Y.; Zhao, J.; Meng, G.
10.1101/2024.05.16.594569 — immunology — Posted on 2024-11-12
3088 A multiplex of connectome trajectories enables several connectivity patterns in parallel
Mostame, P.; Wirsich, J.; Alderson, T. H.; Ridley, B.; Giraud, A.-L.; Carmichael, D.; Vulliemoz, S.; Guye, M.; Lemieux, L.; Sadaghiani, S.
10.1101/2022.06.17.496647 — neuroscience — Posted on 2024-11-12
3090 Separate timescales for spatial and anatomical information processing during action observation
Waltzing, B. M.; McAteer, S.; Moreno-Verdu, M.; Van Caenegem, E. E.; Du, Y.; Hardwick, R. M.
10.1101/2024.10.07.616993 — neuroscience — Posted on 2024-11-12
3093 An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans
Wu, J.; Xi, J.; Zhu, Z.; Zhao, W.; Peng, Q.; Liu, C.; Cao, Y.; Wan, Z.; Chen, X.; Luan, Y.
10.1101/2024.08.27.610021 — bioengineering — Posted on 2024-11-12
3094 WITHDRAWN: Neurophysiology of Reciprocal Influence of Cognition and Emotion in Pianistic Performances
Higuchi, M. K. K.; Sanchez, T. A.; Ramos, L. R.; Fornari, J. E.; de Araujo, D. B.; Leite, J. P.
10.1101/2023.05.28.542541 — neuroscience — Posted on 2024-11-12
3098 Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila
Dong, P.; Li, Y.; Wang, Y.; Zhao, Q.; Lu, T.; Chen, J.; Guo, T.; Ma, J.; Yang, B.; Wu, H.; Huang, H.
10.1101/2024.07.03.601877 — developmental biology — Posted on 2024-11-12
3101 APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics
Ellis, D. S.; Watanabe, K.; Wilmanski, T.; Lustgarten, M. S.; Ardisson Korat, A. V.; Glusman, G.; Hadlock, J. J.; Fiehn, O.; Sebastiani, P.; Price, N. D.; Hood, L.; Magis, A. T.; Evans, S. J.; Pflieger, L.; Lovejoy, J. C.; Gibbons, S. M.; Funk, C. C.; Baloni, P.; Rappaport, N.
10.1101/2024.10.17.618322 — systems biology — Posted on 2024-11-12
3102 The contribution of mitochondria-associated ER membranes to cholesterol homeostasis
Montesinos, J.; Kabra, K.; Uceda, M.; Larrea, D.; Agrawal, R. R.; Tamucci, K.; Pera, M.; Ferre, A. C.; Gomez-Lopez, N.; Yun, T. D.; Velasco, K. R.; Schon, E. A.; Area-Gomez, E.
10.1101/2024.11.11.622945 — cell biology — Posted on 2024-11-11
3103 Neutrophil extracellular traps promote tumor chemoresistance to anthracyclines
Lin, C.; Herlihy, S. E.; Li, M.; Deng, H.; Kim, R.; Bernabei, L.; Rosenwasser, M.; Gabrilovich, D. I.; Vogl, D. T.; Nefedova, Y.
10.1101/2024.11.07.622533 — cancer biology — Posted on 2024-11-11
3104 Expression divergence in response to sex-biased selection
Grieshop, K.; Liu, M. J.; Frost, R. S.; Lindsay, M. P.; Bayoumi, M.; Brengdahl, M. I.; Molnar, R. I.; Agrawal, A. F.
10.1101/2024.11.11.622976 — evolutionary biology — Posted on 2024-11-11
3105 Excitatory Cortical Neurons from CDKL5 Deficiency Disorder Patient-Derived Organoids Show Early Hyperexcitability Not Identified in Neurogenin2 Induced Neurons
Glass, M. R.; Whye, D.; Anderson, N. C.; Wood, D.; Makhortova, N. R.; Polanco, T.; Kim, K. H.; Donovan, K. E.; Vaccaro, L.; Jain, A.; Cacchiarelli, D.; Sun, L.; Olson, H.; Buttermore, E. D.; Sahin, M.
10.1101/2024.11.11.622878 — neuroscience — Posted on 2024-11-11
3108 Hunger modulates exploration through suppression of dopamine signaling in the tail of striatum
Kamath, T.; Lodder, B.; Bilsel, E.; Green, I.; Dalangin, R.; Capelli, P.; Raghubardayal, M.; Legister, J.; Hulshof, L. G.; Wallace, J. B.; Tian, L.; Uchida, N.; Watabe-Uchida, M.; Sabatini, B. L.
10.1101/2024.11.11.622990 — neuroscience — Posted on 2024-11-11
3110 Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion
Yang, X.; Yang, T.; Zhang, Z.; Zhang, Y.; Mei, X.; Gao, Y.; Wang, N.; Jiang, G.; Xu, Y.; Shen, Q.; Medema, M. H.; Wei, Z.; Jousset, A.
10.1101/2024.11.04.621791 — ecology — Posted on 2024-11-11
3113 Prothrombin prevents fatal T cell-dependent anemia during chronic virus infection of mice
Cantrell, R.; Feldman, H. A.; Rosenfeldt, L.; Ali, A.; Gourley, B.; Sprague, C.; Leino, D.; Crosby, J.; Revenko, A.; Monia, B.; Waggoner, S. N.; Palumbo, J.
10.1101/2024.11.11.623028 — immunology — Posted on 2024-11-11
3114 Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
Chedid, J.; Li, Y.; Labrador-Garrido, A.; Abu-Bonsrah, D.; Pavan, C.; Fraser, T.; Ovchinnikov, D.; Zhong, M.; Davis, R.; Strbenac, D.; Johnston, J. A.; Thompson, L. H.; Kirik, D.; Parish, C.; Halliday, G.; Sue, C.; Wali, G.; Dzamko, N.
10.1101/2024.10.07.617117 — neuroscience — Posted on 2024-11-11
3119 Antimicrobial susceptibility testing of Clostridioides difficile: a dual-site study of three different media and three therapeutic antimicrobials
Freeman, J.; Sanders, I. M. J. G.; Harmanus, C.; Clark, E. V.; Berry, A. M.; Smits, W. K.; ESCMID Study Group on C. difficile (ESGCD),
10.1101/2024.11.11.622946 — microbiology — Posted on 2024-11-11
3120 Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks
Mennillo, E.; Lotstein, M. L.; Lee, G.; Johri, V.; Ekstrand, C.; Tsui, J.; Hou, J.; Leet, D. E.; He, J. Y.; Mahadevan, U.; Eckalbar, W. L.; Oh, D. Y.; Fragiadakis, G. K.; Kattah, M. G.; Combes, A.
10.1101/2024.11.11.623014 — immunology — Posted on 2024-11-11
3121 Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination
de Menezes, M. N.; Ge, Z.; Cozijnsen, A.; Gras, S.; Bertolino, P.; Caminschi, I.; Lahoud, M. H.; Yui, K.; McFadden, G. I.; Beattie, L.; Heath, W. R.; Fernandez-Ruiz, D.
10.1101/2024.11.08.622604 — immunology — Posted on 2024-11-11
3122 Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI
Autio, J. A.; Kimura, I.; Ose, T.; Matsumoto, Y.; Ohno, M.; Urushibata, Y.; Ikeda, T.; Glasser, M. F.; Van Essen, D. C.; Hayashi, T.
10.1101/2024.05.16.594068 — neuroscience — Posted on 2024-11-11
3124 Natural Language Prompts Guide the Design of Novel Functional Protein Sequences
Praljak, N.; Yeh, H.; Moore, M.; Socolich, M.; Ranganathan, R.; Ferguson, A. L.
10.1101/2024.11.11.622734 — synthetic biology — Posted on 2024-11-11
3126 Elovl1 inhibition reduced very long chain fatty acids in a mouse model of adrenoleukodystrophy
Huang, J.; Freed, B.; Hanus, M.; Chiang, M. S. R.; Brezzani, A.; Luo, Y.; Li, Y.; Lam, B.; Holley, S.; Gans, J.; Dostalova, Z.; Tang, B.; Phaneuf, C.; Teeple, E.; Parisi, L.; Guo, L.; Zhao, Z.; Kinton, S. N.; Dwyer, J.; Teixeira, S.; Ma, H.; Asmussen, G.; McLaren, R.; Wang, D.; Baker, A.; Siegel, C. S.; Fink, D.; Randall, K.; Belenky, A.; Venugopal, S.; Gaglia, G.; Johnson, J.; Bangari, D. S.; Sardi, S. P.; Zhang, B.; Michel, A.; Proto, J. D.; Kloss, A.; Gladysheva, T.; Kayatekin, C.
10.1101/2024.11.11.622837 — pharmacology and toxicology — Posted on 2024-11-11
3129 In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor
Alves, C. R. R.; Das, S.; Krishnan, V.; Ha, L. L.; Fox, L. R.; Stutzman, H. E.; Shamber, C. E.; Kalailingam, P.; McCarthy, S.; Lino Cardenas, C. L.; Fong, C. E.; Imai, T.; Mitra, S.; Yun, S.; Wood, R. K.; Benning, F. M. C.; Lawton, J.; Kim, N.; Silverstein, R. A.; Ferreira da Silva, J.; de la Cruz, D.; Richa, R.; Malhotra, R.; Chung, D. Y.; Chao, L. H.; Tsai, S. Q.; Maguire, C. A.; Lindsay, M. E.; Kleinstiver, B. P.; Musolino, P. L.
10.1101/2024.11.11.621817 — bioengineering — Posted on 2024-11-11
3130 U1 snRNP-Specific U1C Acts as the Gatekeeper of the Survival of Motor Neurons (SMN) Complex in snRNP Biogenesis
Ngu, D. M.; Myti, S.; Khan, A. A.; Keita, J.; Moore, T.; Andega, P.; Aziz, A.; Raj, R.; Park, M.; Johnson-Winters, K.; Yong, J.; So, B. R.
10.1101/2024.11.11.623077 — biochemistry — Posted on 2024-11-11
3131 A genome resource for the marine annelid Platynereis dumerilii
Mutemi, K. N.; Simakov, O.; Pan, L.; Santangeli, L.; Null, R. W.; Handberg-Thorsager, M.; Vellutini, B. C.; Peterson, K. J.; Fromm, B.; Larsson, T.; Savage, E. L.; Lopez, M. O.; Hercog, R.; Provaznik, J.; Ordonez-Rueda, D.; Azevedo, N.; Gazave, E.; Vervoort, M.; Tomancak, P.; Tan, W.; Winkler, S.; Benes, V.; Hui, J.; Helm, C.; Ozpolat, B. D.; Arendt, D.
10.1101/2024.06.21.600153 — genomics — Posted on 2024-11-11
3132 Patterns of crossover distribution in Drosophila mauritiana necessitate a re-thinking of the centromere effect on crossing over
Hawley, R. S.; Price, A.; Li, H.; Jagannathan, M.; Staber, C.; Hughes, S. E.; Williams, S.; Perera, A.; Egidy, R. R.; Lawlor, A.; Blumenstiel, J. P.
10.1101/2024.11.11.623017 — genetics — Posted on 2024-11-11
3134 Regulation of bicoid mRNA throughout oogenesis and early embryogenesis impacts protein gradient formation
Athilingam, T.; Wilby, E.; Bensidoun, P.; Trullo, A.; Verbrugghe, M.; Lagha, M.; Saunders, T. E.; Weil, T.
10.1101/2024.11.11.622966 — developmental biology — Posted on 2024-11-11
3135 Axonal organelle buildup from loss of AP-4 complex function causes exacerbation of amyloid plaque pathology and gliosis in Alzheimers disease mouse model
Orlowski, A.; Karippaparambil, J.; Paumier, J.-M.; Ghanta, S.; Pallares, E.; Chandran, R.; Edmison, D.; Tandukar, J.; Gao, R.; Gowrishankar, S.
10.1101/2024.03.31.587499 — cell biology — Posted on 2024-11-11
3136 NLRP1 is activated by palmitic acid and induced in human metabolic dysfunction-associated steatohepatitis
Pinilla, M.; Campos-Banos, E.; Martinez-Sanchez, M. A.; Sanchez-Villalobos, M.; Oliva-Bolarin, A.; Rico-Chazarra, S.; Ruiz-Alcaraz, A. J.; Martinez, C. M.; Mika, A.; Frutos, M. D.; Ramos-Molina, B.; Nunez-Sanchez, M. A.; Perez-Oliva, A. B.
10.1101/2024.11.11.622769 — molecular biology — Posted on 2024-11-11
3139 Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence
Franklin, D.; Chen, Y.-W.; Chen, Y.; Wittchen, M.; Agnew, A.; Luu, A.; Whitelegge, J.; Zhou, Z. H.; Tauch, A.; Das, A.; Ton-That, H.
10.1101/2024.11.11.623001 — microbiology — Posted on 2024-11-11
3140 Measuring Growth, Resistance and Recovery after Artemisinin Treatment of Plasmodium falciparum in a semi-high-throughput Assay
Sievert, M. A.; Singh, P. P.; Shoue, D. A.; Needham, L. A. C.; Brenneman, K. M.; Qahash, T.; Cassady, Z.; Kumar, S.; Li, X.; Nosten, F. H.; Anderson, T. J.; Vaughan, A. M.; Romero-Severson, J.; Ferdig, M. T.
10.1101/2024.11.11.623064 — microbiology — Posted on 2024-11-11
3143 Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis
Male, F.; Kegawa, Y.; Blank, P. S.; Jimenez Munguia, I.; Sidik, S. M.; Valleau, D.; Lourido, S.; Lebrun, M.; Zimmerberg, J.; Ward, G. E.
10.1101/2024.10.12.618018 — microbiology — Posted on 2024-11-11
3144 Single molecule imaging of transcription dynamics, RNA localization and fate in T cells
Lattanzio, M. V.; Sostaric, N.; Kanagasabesan, N.; Popovic, B.; Bradaric, A.; Wardak, L.; Guislain, A.; Savakis, P. E.; Tutucci, E.; Wolkers, M. C.
10.1101/2024.11.11.622939 — immunology — Posted on 2024-11-11
3145 Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism
Li, M.; Jin, H.; Liu, Y.; Wang, Z.; Li, L.; Wang, T.; Wang, X.; Zhang, H.; Huo, B.; Yu, T.; Wang, S.; Zhao, W.; Liu, J.; Huang, P.; Cui, J.; Xia, X.
10.1101/2024.11.11.622956 — immunology — Posted on 2024-11-11
3146 Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity
O'Toole, K.; Guetta, L.; Urbanaviciute, P.; Suklai, P.; Wright, C.; Fisher, T.; Liddelow, S.; Luisier, R.; Marzi, S. J.; Serio, A.
10.1101/2024.11.11.622998 — neuroscience — Posted on 2024-11-11
3147 Tic-related behaviors in Celsr3 mutant mice are contributed by alterations of striatal D3 dopamine receptors
Cadeddu, R.; Branca, C.; Braccagni, G.; Musci, T.; Piras, I. S.; Anderson, C. J.; Capecchi, M. R.; Huentelman, M. J.; Moos, P. J.; Bortolato, M.
10.1101/2023.12.07.570669 — neuroscience — Posted on 2024-11-11
3149 AlphaBind, a Domain-Specific Model to Predict and Optimize Antibody-Antigen Binding Affinity
Agarwal, A. A.; Harrang, J.; Noble, D.; McGowan, K. L.; Lange, A. W.; Engelhart, E.; Lahman, M. C.; Adamo, J.; Yu, X.; Serang, O.; Minch, K. J.; Wellman, K. Y.; Younger, D. A.; Lopez, R. M.; Emerson, R. O.
10.1101/2024.11.11.622872 — synthetic biology — Posted on 2024-11-11
3155 Acute myeloid leukemia mitochondria hydrolyze ATP to resist chemotherapy
Hagen, J. T.; Montgomery, M.; Aruleba, R.; Chrest, B.; Green, T. D.; Kassai, M.; Zeczycki, T.; Schmidt, C. A.; Bhowmick, D.; Tan, S.-F.; Feith, D.; Chalfant, C.; Loughran, T.; Liles, D.; Minden, M.; Schimmer, A.; Cabot, M.; McClung, J.; Fisher-Wellman, K.
10.1101/2024.04.12.589110 — cancer biology — Posted on 2024-11-11
3157 Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats
Kuhn, B. N.; Cannella, N. N.; Chitre, A.; Nguyen, K.-M. H.; Cohen, K.; Chen, D.; Peng, B.; Ziegler, K. S.; Lin, B.; Johnson, B.; Missfeldt Sanchez, T.; Crow, A. D.; Lunerti, V.; Gupta, A.; Dereschewitz, E.; Soverchia, L.; Hopkins, J. L.; Roberts, A. T.; Ubaldi, M.; Abdulmalek, S.; Kinen, A.; Hardiman, G.; Chung, D.; Polesskaya, O.; Solberg-Woods, L.; Ciccocioppo, R.; Kalivas, P.; Palmer, A. A.
10.1101/2024.02.27.582340 — genetics — Posted on 2024-11-11
3159 Ectopic transcription due to inappropriately inherited histone methylation may interfere with the ongoing function of terminally differentiated cells
Rodriguez, J. D.; Reeves, M. N.; Wang, H.-L. V.; Chavez, J. Z.; Rastogi, R.; Chavez, S. R.; Preston, E. A.; Chadha, M. S.; Sun, L. I.; Hill, E. J.; Corces, V. G.; Schmeichel, K. L.; Murray, J. I.; Katz, D. J.
10.1101/2023.10.29.564525 — developmental biology — Posted on 2024-11-11
3164 Newly discovered and conserved role of IgM against viral infection in an early vertebrate
Kong, W.; Wang, X.; Ding, G.; Yang, P.; Shi, Y.; Cai, C.; Yang, X.; Cheng, G.; TTakizawa, F.; XU, Z.
10.1101/2024.11.11.622905 — immunology — Posted on 2024-11-11
3165 Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation
Winanto, W.; Tan, L.-Y.; Choi, W. H.; Lee, C. Y.-P.; Ho, W.-Y.; Lim, Y.-S.; Soh, B. S.; Sanford, E.; Tan, C.-L.; Liou, Y.-C.; Huang, C. C.-Y.; Ling, S.-C.; Ng, S.-Y.
10.1101/2024.11.11.622894 — neuroscience — Posted on 2024-11-11
3167 Spatio-temporal dynamics of the fibrotic niche in cardiac repair
Grün, D.; Chan, A. S. F.; Greiner, J.; Brennan, T.; Agrawal, A.; Hemmer, H.; Sinning, K.; Marschhäuser, L.; Cheung, W. L.; Iqbal, Z.; Klesen, A.; Seidel, T.; Vaeth, M.; Rog-Zielinska, E.; Kohl, P.; Schneider-Warme, F.
10.1101/2024.11.10.622609 — systems biology — Posted on 2024-11-11
3169 ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
Garcia Garcia, A.; Ferrer Aporta, M.; Vallejo Palma, G.; Giraldez Trujillo, A.; Castillo-Gonzalez, R.; Calzon Lozano, D.; Mora Perdiguero, A.; Munoz Velasco, R.; Colina Castro, M.; de Simone Benito, E.; Torres-Ruiz, R.; Rodriguez-Perales, S.; Dehairs, J.; V Swinnen, J.; Garcia-Canaveras, J. C.; Lahoz, A.; Montalvo Quiros, S.; del Pozo-Rojas, C.; Luque Rioja, C.; Monroy Munoz, F.; Herraez-Aguilar, D.; Alonso Riano, M.; Rodriguez Peralto, J. L.; Sanchez-Arevalo Lobo, V. J.
10.1101/2024.11.11.622928 — cancer biology — Posted on 2024-11-11
3173 Absence of CDK12 in oocyte leads to female infertility
Jansova, D.; Sedmikova, V.; Berro, F. J.; Aleshkina, D.; Dvoran, M.; Kubelka, M.; Rezacova, J.; Rutanova, J.; Kohoutek, J.; Susor, A.
10.1101/2024.11.11.622910 — developmental biology — Posted on 2024-11-11
3175 A regulator controls both DNA damage response and anti-phage defense networks in Moraxellaceae
Song, S.; Zhong, S.; Shi, Q.; Zheng, X.; Yao, Y.; Wang, W.; Chen, S.; Huang, Z.; An, D.; Xu, H.; Tian, B.; Zhao, Y.; Wang, L.; Zhang, W.; Hua, X.; Yu, Y.; Lu, H.; Fan, L.; Hua, Y.
10.1101/2024.11.11.622897 — microbiology — Posted on 2024-11-11
3177 Correlative humoral and cellular immunity to genetically attenuated malaria parasites in humans
Colstrup, E.; Nakajima, R.; Krol, J. M. M.; Lamers, O. A. C.; Ramiro De Assis, R.; Jain, A.; Jasinskas, A.; Iliopoulou, E.; de Bes-Roeleveld, H. M.; Franke-Fayard, B. M. D.; Roestenberg, M.; Felgner, P. L.; Murugan, R.
10.1101/2024.11.11.622940 — immunology — Posted on 2024-11-11
3178 Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines
Chen, W.; Tompkins, K. R.; Windsor, I. W.; Martinez, L. T.; Ramos, M.; Li, W.; Shrivastava, S.; Rajput, S.; Chang, J. S.; Sahasrabudhe, P.; Fennell, K. F.; McLellan, T. J.; West, G. M.; Dizon, K. P.; Yam, A.; Mitra, S.; Saha, S.; Sharaf, D.; McKeen, A. P.; Cadima, C. I.; Muik, A.; Swanson, W.; Moreno, R. M.; Daroca, P. M.; Sahin, U.; Anderson, A. S.; Wu, H.; Swanson, K. A.; Modjarrad, K.
10.1101/2024.11.04.621927 — immunology — Posted on 2024-11-11
3184 When no answer is better than a wrong answer: a causal perspective on batch effects
Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Xu, T.; Milham, M.; Caffo, B.; Vogelstein, J. T.
10.1101/2021.09.03.458920 — neuroscience — Posted on 2024-11-11
3185 Do the shuffle: Expanding the synthetic biology toolkit for shufflon-like recombination systems
Katalinic, J.; Richards, M.; Auyang, A.; Millett, J. H.; Kogenaru, M.; Windbichler, N.
10.1101/2024.10.25.620183 — synthetic biology — Posted on 2024-11-11
3186 Root metaxylem area influences drought tolerance and transpiration in pearl millet in a soil texture dependent manner
Affortit, P.; Faye, A.; Jones, D. H.; Benson, E.; Sine, B.; Burridge, J.; Ndoye, S.; Barry, L.; Moukouanga, D.; Barnard, S.; Bhosale, R.; Pridmore, T.; Gantet, P.; Vadez, V.; Cubry, P.; Kane, N. A.; Bennett, M. J.; Atkinson, J. J.; Laplaze, L.; Wells, D. M.; Grondin, A.
10.1101/2024.11.09.622826 — physiology — Posted on 2024-11-11
3188 ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images
Wu, E.; Bieniosek, M.; Wu, Z.; Thakkar, N.; Charville, G. W.; Makky, A.; Schürch, C.; Huyghe, J. R.; Peters, U.; Li, C. I.; Li, L.; Giba, H.; Behera, V.; Raman, A.; Trevino, A. E.; Mayer, A. T.; Zou, J.
10.1101/2024.11.10.622859 — pathology — Posted on 2024-11-11
3192 Deep Learning with Evolutionary Scale Modeling to discover Antibiotic-Resistance Drug against Klebsiella Pneumoniae
Jin, L.; Lei, Z.; Lin, P.; Ma, C.; Zhang, W.; Zhou, J.; Meng, S.; Jiang, Z.; Bu, Y.; Xu, Y.; Wei, N.; Hsu, T.; Qin, G.; Qiu, H.
10.1101/2024.11.09.622818 — bioinformatics — Posted on 2024-11-11
3193 Assessing Conformation Validity and Rationality of Deep Learning-Generated 3D Molecules
Fan, F.; Xi, B.; Meng, X.; Wang, H.; Zhang, B.; Xu, Q.; Feng, W.; Wang, X.; Zhang, H.; Zhou, F.; Liu, Z.; Zhou, W.; Huang, B.
10.1101/2024.11.10.622844 — bioinformatics — Posted on 2024-11-11
3194 Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo
Ye, T.; Alamgir, A.; Robertus, C.; Colina, D.; Monticello, C.; Donahue, T. C.; Hong, L.; Vincoff, S.; Goel, S.; Fekkes, P.; Camargo, L. M.; Lam, K.; Heyes, J.; Putnam, D.; Alabi, C. A.; Chatterjee, P.; DeLisa, M. P.
10.1101/2024.11.10.622803 — bioengineering — Posted on 2024-11-11
3198 Single-nucleus multiple-organ chromatin accessibility mapping in the rat
Li, R.; Yuan, Y.; Duan, S.; Deng, Q.; Ma, W.; Liu, C.; Gao, P.; Lu, L.; Liu, C.
10.1101/2024.11.11.622900 — genomics — Posted on 2024-11-11
3199 Different alterations in mRNP composition trigger an increase in harmful R-loops
Merida-Cerro, J. A.; Chevreux, G.; Palancade, B.; Rondon, A. G.; Aguilera, A.
10.1101/2024.11.11.622913 — genetics — Posted on 2024-11-11
3200 Evolutionary history of the grape sex-determining region in angiosperms and emergence of dioecy in Vitaceae
Massonnet, M.; Cochetel, N.; Ricciardi, V.; Minio, A.; Figueroa-Balderas, R.; Londo, J.; Cantu, D.
10.1101/2024.11.10.622717 — evolutionary biology — Posted on 2024-11-11
3201 Footprints of worldwide adaptation in structured populations of D. melanogaster through the expanded DEST 2.0 genomic resource
Nunez, J. C. B.; Coronado-Zamora, M.; Gautier, M.; Kapun, M.; Steindl, S.; Ometto, L.; Hoedjes, K. M.; Beets, J.; Wiberg, R. A. W.; Mazzeo, G. R.; Bass, D. J.; Radionov, D.; Kozeretska, I.; Zinchenko, M.; Protsenko, O.; Serga, S.; Amor-Jimenez, C.; Casillas, S.; Sanchez-Gracia, A.; Patenkovic, A.; Glaser-Schmitt, A.; Barbadilla, A.; Buendia-Ruiz, A. J.; Bertelli, A. C.; Kiss, B.; Önder, B. S.; Matrin, B. R.; Wertheim, B.; Deschamps, C.; Arboleda-Bustos, C. E.; Tinedo, C.; Feller, C.; Schlötterer, C.; Lawler, C.; Fricke, C.; Vieira, C. P.; Vieira, C.; Obbard, D. J.; Orengo, D.; Vela, D.; Amat
10.1101/2024.11.10.622744 — evolutionary biology — Posted on 2024-11-11
3207 Disproportionate regulation of wildlife trade
Challender, D.; Mallon, D.; 't Sas-Rolfes, M.; Dickman, A.; Hare, D.; Hart, A. G.; Mandisodza-Chikerema, R.; Roe, D.; Mbaiwa, J.; Hoffmann, M.
10.1101/2024.11.11.622931 — ecology — Posted on 2024-11-11
3209 The Microbial Ecology of Serpentinites
Colman, D. R.; Boyd, E. S.; Templeton, A. S.; Spear, J. R.
10.1101/2024.11.10.622848 — microbiology — Posted on 2024-11-11
3210 Insect-specific Alphamesonivirus-1 (Mesoniviridae) in lymph node and lung tissues from two horses with acute respiratory syndrome
Jurisic, L.; Auerswald, H.; Marcacci, M.; Di Giallonardo, F.; Coetzee, L. M.; Curini, V.; Averaimo, D.; Di Teodoro, G.; Ortiz-Baez, A. S.; Camma, C.; Richt, J. A.; Holmes, E. C.; Lorusso, A.
10.1101/2024.11.10.622896 — microbiology — Posted on 2024-11-11
3211 Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC
Smith, B. J.; Zhao, C.; Dubinkina, V.; Jin, X.; Zahavi, L.; Shoer, S.; Moltzau-Anderson, J.; Segal, E.; Pollard, K.
10.1101/2024.04.10.588779 — microbiology — Posted on 2024-11-11
3212 Rare and novel RELA variants are common in systemic autoimmunity
Downes, M. B.; Nambadan, S. B.; Chow, J.; Davies, A.; Hart, G.; Andrews, T. D.; Lehmann, N.; Bales, I.; Vengatasalam, A.; Kitching, A. R.; Walters, G.; Athanasopoulos, V.; Jiang, S.
10.1101/2024.11.11.622574 — immunology — Posted on 2024-11-11
3213 A Watershed Algorithm GUI for Personalized fMRI-guided rTMS Target
Feng, Z.-j.; Wei, Z.; Hong, L.; Fang, H.; Han, Y.; Yang, P.; Lv, D.; Zang, Y.-f.
10.1101/2024.11.10.622836 — neuroscience — Posted on 2024-11-11
3215 Cross-sectional brain age assessments are limited in predicting future brain change
Korbmacher, M.; Vidal-Pineiro, D.; Wang, M.-Y.; van der Meer, D.; Wolfers, T.; Nakua, H.; Eikefjord, E.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2024.09.11.612523 — neuroscience — Posted on 2024-11-11
3217 Free water elimination tractometry for aging brains
Chang, K. H.; Burke, L.; LaPiana, N.; Howlett, B.; Hunt, D.; Dezelar, M.; Andre, J. B.; Curl, P.; Ralston, J. D.; Rokem, A.; MacDonald, C. L.
10.1101/2024.11.10.622861 — neuroscience — Posted on 2024-11-11
3218 Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata)
Peichl, L.; Meimann, S.; Solovei, I.; Gügel, I. L.; Geiger, C.; Schauerte, N.; Gozdziewska-Harłajczuk, K.; Kleckowska-Nawrot, J. E.; Wibbelt, G.; Haverkamp, S.
10.1101/2024.11.09.622767 — zoology — Posted on 2024-11-11
3220 Multi-omics Analysis Reveals Important Role for Microbial-derived Metabolites from Botryllus schlosseri in Metal Interactions
Matus, D. G. G.; Donaghy, C. M.; Vijayan, N.; Lane, Z. T.; Howell, M.; Glavin, G. G.; Angeles-Boza, A. M.; Nyholm, S. V.; Balunas, M. J.
10.1101/2024.11.10.622856 — systems biology — Posted on 2024-11-11
3223 Sex-dependent additive effects of dorzagliatin and incretin on insulin secretion in a novel mouse model of GCK-MODY
Salazar, S.; Delgadillo-Silva, L. F.; Carapeto, P.; Dakessian, K.; Melhem, R.; Provencher-Girard, A.; Ostinelii, G.; Turgeon, J.; Kaci, I.; Migneault, F.; Huising, M. O.; Hibert, M.-J.; Rutter, G. A.
10.1101/2024.11.09.622781 — physiology — Posted on 2024-11-11
3225 Prenatal Arsenic Exposure and Gene Expression in Fetal Liver, Heart, Lung, and Placenta
Rychlik, K. A.; Kashiwagi, C. M.; Liao, J.-S.; Mathur, A.; Illingworth, E. J.; Sanchez, S. S.; Kleensang, A.; Maertens, A.; Sille, F. C. M.
10.1101/2024.11.10.622821 — pharmacology and toxicology — Posted on 2024-11-11
3226 scLong: A Billion-Parameter Foundation Model for Capturing Long-Range Gene Context in Single-Cell Transcriptomics
Bai, D.; Mo, S.; Zhang, R.; Luo, Y.; Gao, J.; Yang, J. P.; Wu, Q.; Singh, D.; Rahmani, H.; Amariuta, T.; Grotjahn, D.; Zhong, S.; Lewis, N.; Wang, W.; Ideker, T.; Xing, E.; Xie, P.
10.1101/2024.11.09.622759 — bioinformatics — Posted on 2024-11-11
3230 Assessment of the Genetic Diversity of Atlantic Bottlenose Dolphin (Tursiops truncatus) Strandings in the Mississippi Sound (USA)
Arick, M.; Landrau-Giovannetti, N.; Hsu, C.-Y.; Grover, C. E.; Reichley, S.; Magbanua, Z. V.; Pechanova, O.; Moore, D.; Kayal, E.; Linhoss, A.; Madrigal, T.; Peterman, M.; Ozdemir, O.; Peterson, D. G.; Solangi, M.; Lawrence, M.; Karsi, A.
10.1101/2024.11.09.622766 — genomics — Posted on 2024-11-11
3231 DAF-16/Foxo suppresses the transgenerational sterility of prg-1 piRNA mutants via a systemic small RNA pathway
Simon, M.; Spichal, M.; Heestand, B.; Frenk, S.; Hedges, A.; Godwin, M.; Wellman, A.; Sakaguchi, A.; Ahmed, S.
10.1101/326751 — genetics — Posted on 2024-11-11
3233 Ecological synchrony in human-modified landscapes under a changing climate
Song, Y.; Barnes, M.; Browning, D. M.; Bybee-Finley, K. A.; Dahlin, K. M.; Munch, S. B.; Ponce-Campos, G. E.; Youngflesh, C.; Zuckerberg, B.; Zhu, K.
10.1101/2024.11.09.621137 — ecology — Posted on 2024-11-11
3234 Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity
Wang, Y.; Sen-Majumdar, A.; Li, J.-M.; Sarkar, S.; Passang, T.; Li, Y.; Cohen, J.; Chen, Z.; Chaudagar, K.; Das, P. K.; Wang, S.; Bruk, N.; Papadantonakis, N.; Giver, C.; Waller, E. K.
10.1101/2024.11.08.622716 — immunology — Posted on 2024-11-11
3235 Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination
de Menezes, M. N.; Ge, Z.; Cozijnsen, A.; Gras, S.; Bertolino, P.; Caminschi, I.; Lahoud, M. H.; Yui, K.; McFadden, G. I.; Beattie, L.; Heath, W. R.; Fernandez-Ruiz, D.
10.1101/2024.11.08.622604 — immunology — Posted on 2024-11-11
3245 Enhanced lentiviral gene delivery to mammalian cells via paired cell surface and viral envelope engineering
Tannir, R.; Chan, L.; Grzywa, T. M.; Arevalo, O.; Neeser, A.; Kahn, S.; Cozzone, A.; Olenick, L.; Mason, N. J.; Ma, L.
10.1101/2024.11.08.622723 — bioengineering — Posted on 2024-11-11
3249 Genetic modulation of yield and phenotypic plasticity of yield in winter wheat
Giordano, N.; Sadras, V.; Guttieri, M. J.; Cruppe, G.; Bai, G.; Fritz, A.; Bernardo, A.; St Amand, P.; Abbate, P.; Berger, A.; Boehm, J.; de Oliveira Silva, A.; Jones-Diamond, S.; Haley, S.; Lingenfelser, J.; Zhang, G.; Lollato, R.
10.1101/2024.11.08.622708 — genetics — Posted on 2024-11-11
3254 Rapid Caspian sea level decline requires dynamic spatio-temporal conservation planning to keep biodiversity protection measures relevant
Court, R.; Lattuada, M.; Shumeyko, N.; Baimukanov, M.; Eybatov, T.; Kaidarova, A.; Mamedov, E. V.; Rustamov, E.; Tasmagambetova, A.; Prange, M.; Wilke, T.; Hassall, C.; Goodman, S. J.
10.1101/2024.11.08.622693 — ecology — Posted on 2024-11-11
3258 Florigen and antiflorigen gene expression correlates with reproductive state in a marine angiosperm, Zostera marina
Nolan, C. T.; Campbell, I.; Farrell-Sherman, A.; Briones Ortiz, B. A.; Naish, K. A.; Di Stilio, V.; Kaldy, J. E.; Donoghue, C.; Ruesink, J. L.; Imaizumi, T.
10.1101/2024.11.09.622789 — plant biology — Posted on 2024-11-11
3259 Apoplast metabolomics reveals that plant-pathogen crosstalk is modulated by nitrogen supply
Jeridi, R.; Daviere, A.; Jolivet, S.; Zarattini, M.; Clement, G.; Soulie, M.-C.; Landoulsi, A.; Fagard, M.
10.1101/2024.11.11.622918 — plant biology — Posted on 2024-11-11
3260 Sex differences in the cardiopulmonary and neuromuscular response to high-intensity interval exercise
Wilson, H.; Bernert, L.; Spillane, P.; Squires, E.; Crawford, L.; Piasecki, J.; Julian, R.; Wilhelm, E. N.; Hicks, K. M.; Ansdell, P.
10.1101/2024.11.08.622119 — physiology — Posted on 2024-11-11
3262 Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil.
Hubbe, A.; Pestle, W.; Hubbe, M.; Amirali, A.; Chin, E. N.; de Oliveira, R. E.; Pinto Sandoval, E. D.; Neves, W. A.
10.1101/2024.11.08.621301 — paleontology — Posted on 2024-11-11
3264 Ligand-independent c-Met activation by HHLA2 drives hepatocellular carcinoma and predicts c-MET inhibitor efficacy
huang, x.; fang, r.; pang, y.; zhang, z.; huang, j.; li, y.; yuan, t.; zeng, y.; yao, z.; Thinwa, J.; Vega-Rubin-de-Celis, S.; shen, h.; wang, j.; shen, f.; wei, y.
10.1101/2024.11.07.622557 — cancer biology — Posted on 2024-11-11
3265 Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS
Jang, H. J.; Urrutia, G.; Orskov, A. D.; Kim, H. J.; Nelson, S. A.; Nguyen, A. V.; Lee, H.; Burgos, R. S.; Johnson, B. K.; Wegener, M.; Becker, K.; Adams, M.; Sheridan, R.; Ramjan, Z. H.; Givan, S. A.; Zebley, C. C.; Youngblood, B.; Issa, J.-P.; Topper, M. J.; Baer, M. R.; Baylin, S. B.; Triche, T. J.; O'Connell, C. L.; Gronbaek, K.; Jones, P. A.
10.1101/2024.11.08.622670 — cancer biology — Posted on 2024-11-11
3266 Healthy B cells: allies or adversaries of CAR-T cell immunotherapy?
Paixao, E. A.; Barros, L. R. C.; Cesar Fassoni, A.; Almeida, R. C. C. d.
10.1101/2024.11.08.622644 — cancer biology — Posted on 2024-11-11
3267 Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse
Ho, T.-C.; LaMere, M. W.; Kawano, H.; Byun, D. K.; LaMere, E. A.; Chiu, Y.-C.; Chen, C.; Wang, J.; Dokholyan, N. V.; Calvi, L. M.; Liesveld, J. L.; Jordan, C. T.; Kapur, R.; Singh, R. K.; Becker, M. W.
10.1101/2024.11.09.622796 — cancer biology — Posted on 2024-11-11
3269 Distilling structural representations into protein sequence models
Ouyang-Zhang, J.; Gong, C.; Zhao, Y.; Krähenbühl, P.; Klivans, A. R.; Diaz, D. J.
10.1101/2024.11.08.622579 — bioinformatics — Posted on 2024-11-11
3271 A robust workflow to benchmark deconvolution of multi-omic data
Amblard, E.; Bertrand, V.; Martin Pena, L.; Karkar, S.; Chuffart, F.; Ayadi, M.; Baures, A.; Armenoult, L.; Kermezli, Y.; Cros, J.; Blum, Y.; Richard, M.
10.1101/2024.11.08.622633 — bioinformatics — Posted on 2024-11-11
3277 RNA-Protein Interaction Classification via Sequence Embeddings
Matus, D.; Runge, F.; Franke, J. K. H.; Gerne, L.; Uhl, M.; Backofen, R.; Hutter, F.
10.1101/2024.11.08.622607 — bioinformatics — Posted on 2024-11-11
3278 Considerations for Cell Type Heterogeneity in Pediatric Salivary DNA Methylation Analyses: Comparison of Reference Panels & Stratification by Estimated Cell TypeProportion
Chan, M. H.-M.; Meijer, M.; Merrill, S. M.; Fu, M. P. Y.; Lin, D.; MacIsaac, J. L.; Riis, J. L.; Granger, D. A.; Thomas, E. A.; Kobor, M. S.
10.1101/2024.11.08.621377 — bioinformatics — Posted on 2024-11-11
3280 Physical vitrification and nanowarming at human organ scale to enable cryopreservation
Gangwar, L.; Han, Z.; Scheithauer, C.; Namsrai, B.-E.; Kantesaria, S.; Goldstein, R.; Etheridge, M. L.; Finger, E. B.; Bischof, J. C.
10.1101/2024.11.08.622572 — bioengineering — Posted on 2024-11-11
3284 Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction
Chartier, C. A.; Woods, V. A.; Xu, Y.; van Vlimmeren, A. E.; Johns, A. C.; Jovanovic, M.; McDermott, A. E.; Keedy, D. A.; Shah, N. H.
10.1101/2024.07.16.603632 — biochemistry — Posted on 2024-11-11
3286 Disease-Linked Regulatory DNA Variants and Homeostatic Transcription Factors in Epidermis
Porter, D. F.; Meyers, R. M.; Miao, W.; Reynolds, D.; Hong, A. W.; Yang, X.; Mondal, S.; Siprashvili, Z.; Srinivasan, S.; DUCOLI, L.; Meyers, J.; Nguyen, D.; Ko, L.; Kellman, L.; Elfaki, I.; Guo, M.; Winge, M.; Lopez-Pajares, V.; Tao, S.; Khavari, P.
10.1101/2024.11.07.622542 — genetics — Posted on 2024-11-11
3290 Human activity, not environmental factors, drives Scedosporium and Lomentospora distribution in Taiwan
Wu, H.-M.; Fan, Y.-H.; Phang, G.-J.; Zeng, W.-T.; Abdrabo, K. A. E.-S.; Wu, Y.-T.; Sun, P.-L.; Lin, Y.-H.; Huang, Y.-T.
10.1101/2024.11.07.622530 — ecology — Posted on 2024-11-11
3294 Distinct Binding Modes of Inter-Spike Cross-Linking Suggest a Supplementary Mechanism for SARS-CoV-2 Antibody Neutralization
Nan, X.; Li, Y.; Zhang, R.; Wang, R.; LV, N.; Li, J.; Chen, Y.; Zhou, B.; Wang, Y.; Wang, Z.; Zhu, J.; Chen, J.; Li, J.; Chen, W.; Zhang, Q.; Shi, X.; Zhao, C.; Chen, C.; Liu, Z.; Zhao, Y.; Liu, D.; wang, x.; Yan, L.; Li, T.; Zhang, L.; Yang, Y. R.
10.1101/2024.11.07.622402 — immunology — Posted on 2024-11-11
3295 A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope
Srivastava, N.; Vomund, A.; Peterson, O.; Abousaway, O.; Li, T.; Kain, L.; Stone, P.; Clement, C.; Sharma, S.; Zhang, B.; Joglekar, A.; Campisi, L.; Hsieh, C.-S.; Santambrogio, L.; Teyton, L.; Arbelaez, A. M.; Lichti, C.; Wan, X.
10.1101/2024.11.07.622538 — immunology — Posted on 2024-11-11
3296 Long-Read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons
Xu, J.; Hoerner, M.; Buena Atienza, E.; Manibarathi, K.; Nagel, M.; Hauser, S.; Admard, J.; Casadei, N.; Ossowski, S.; Schuele, R.
10.1101/2024.11.08.622610 — neuroscience — Posted on 2024-11-11
3297 Integration of Imaging-based and Sequencing-based Spatial Omics Mapping on the Same Tissue Section via DBiTplus
Enninful, A.; Zhang, Z.; Klymyshyn, D.; Zong, H.; Bai, Z.; Farzad, N.; Su, G.; Baysoy, A.; Nam, J.; Yang, M.; Lu, Y.; Zhang, N.; Braubach, O.; Xu, M. L.; Ma, Z.; Fan, R.
10.1101/2024.11.07.622523 — systems biology — Posted on 2024-11-11
3299 Living xylem cells encode a large number of conserved gene families responsible for vascular sap peptides
Lu, M. R.; Tung, C.-C.; Huang, C.-E.; Chen, C.-H.; Liou, P.-C.; Lin, C.-Y. I.; Yu, J.-H.; Chen, Y.-L.; Lin, Y.-C. J.; Tsai, I. J.
10.1101/2024.11.10.622827 — plant biology — Posted on 2024-11-11
3300 Stalling of the endometrial decidual reaction determines the recurrence risk of miscarriage
Muter, J.; Kong, C.-S.; Taus Nebot, M.; Tryfonos, M.; Vrljicak, P.; Brighton, P. J.; Dimakou, D. B.; Vickers, M.; Yoshihara, H.; Ott, S.; Tan, B. K.; Bennet, P.; Quenby, S.; Richter, A.; Van de Velde, H.; Lucas, E.; Rawlings, T. M.; Brosens, J.
10.1101/2024.11.07.622412 — physiology — Posted on 2024-11-11
3301 Retinoid-impregnated nanoparticles enable control of bone growth by site-specific modulation of endochondral ossification in mice
Matsuoka, M.; Uchibe, K.; Tang, N.; Tian, H.; Suzuki, A.; Oichi, T.; Usami, Y.; Alferiev, I. S.; Otsuru, S.; Abzug, J. M.; Herzenberg, J. E.; Pacifici, M.; Enomoto-Iwamoto, M.; Chorny, M.; Iwamoto, M.
10.1101/2024.11.08.622655 — pharmacology and toxicology — Posted on 2024-11-11
3304 The single-cell spatial landscape of stage III colorectal cancers
Su, A.; Lee, H.; Tran, M.; Cruz, R. d.; Sathe, A.; Bai, X.; Wichmann, I.; Pflieger, L.; Moulton, B.; Barker, T.; Haslem, D.; Jones, D.; Nadauld, L.; Nguyen, Q.; Ji, H.; Rhodes, T.
10.1101/2024.11.07.622577 — cancer biology — Posted on 2024-11-11
3306 Biophysical Basis of Paracellular Barrier Modulation by a Pan-Claudin-Binding Molecule
Ogbu, C. P.; Mandriota, A. M.; Liu, X.; de las Alas, M.; Kapoor, S.; Choudhury, J.; Kossiakoff, A. A.; Duffey, M. E.; Vecchio, A. J.
10.1101/2024.11.10.622873 — biophysics — Posted on 2024-11-11
3311 KaMLs for Predicting Protein pKa Values andIonization States: Are Trees All You Need?
Shen, M.; Kortzak, D.; Ambrozak, S.; Bhatnagar, S.; Buchanan, I.; Liu, R.; Shen, J.
10.1101/2024.11.09.622800 — biophysics — Posted on 2024-11-11
3313 Conformational plasticity of mitochondrial VDAC2 controls the kinetics of its interaction with cytosolic proteins
Rosencrans, W. M.; Khuntia, H.; Larimi, M. G.; Mahalakshmi, R.; Yu, T.-Y. D.; Bezrukov, S. M.; Rostovtseva, T. K.
10.1101/2024.11.08.622687 — biophysics — Posted on 2024-11-11
3315 Comprehensive multi-omics profiling of a healthy human cohort
Visser, C.; Niehues, A.; Najdekr, L.; Toth, R.; Nazarov, P. V.; Vrbkova, J.; Stankova, J.; Ekberg, S.; Moreno, E. C.; Ghimire, B.; Yadav, B.; Mattila, P.; Puhka, M.; Lanza, V. F.; Gloerich, J.; Kulkarni, P.; Wessels, H.; Engelke, U.; Oldoni, E.; Andreu, T.; Saunders, G.; Muller, A.; Bendova, M.; Rozankova, Z.; Dzubak, P.; Srovnal, J.; Pavlis, P.; Siska, B.; Scherer, A.; Bermejo, M. L. G.; Nordlund, J.; Gool, A.; Hajduch, M.; 't Hoen, P. A. C.
10.1101/2024.11.07.622407 — bioinformatics — Posted on 2024-11-11
3319 Accurate prediction of CRISPR editing outcomes in somatic cell lines and zygote with few-shot learning
Zheng, W.; Yu, L.; Wang, G.; Cao, S.; Ho, K.; Song, J.; Cheng, C.; Ho, J. W. K.; Liu, X.; Wu, M.; Liu, Z.; Wang, H.; Liu, P.; Lan, G.; Huang, Y.
10.1101/2024.11.08.622621 — bioinformatics — Posted on 2024-11-11
3320 Genomic evidence suggests the balanced lethal system in Triturus newts originated in an instantaneous speciation event.
France, J. M.; de Visser, M. C.; Arntzen, J. W.; Babik, W.; Cvijanovic, M.; Ivanovic, A.; Smith, J.; Vuicc, T.; Wielstra, B.
10.1101/2024.10.29.620207 — evolutionary biology — Posted on 2024-11-11
3322 ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport
Nakazato, M.; Nakamura, H.; Kato, M.; Ikema, R.; Iguchi, M.; Hanaoka, K.; Eto, K.; Karashima, T.; Ikeda, A.; Yabuki, Y.; Schlarmann, P.; Manzano-Lopez, J.; Aguilera-Romero, A.; Sabido-Bozo, S.; Perez-Linero, A. M.; Kana, M.; Iefuji, H.; Riezman, I.; Riezman, H.; Muniz, M.; Funato, K.
10.1101/2024.11.07.622448 — cell biology — Posted on 2024-11-11
3324 Flavodiiron proteins associate pH-dependently with the thylakoid membrane for ferrdoxin-1 powered O2 photoreduction
Nikkanen, L.; Vakal, S.; Santana-Sanchez, A.; Hubacek, M.; Wang, Y.; Boehm, M.; Gutekunst, K.; Salminen, T. A.; Allahverdiyeva, Y.
10.1101/2023.05.19.541409 — plant biology — Posted on 2024-11-11
3326 Why the brown ghost chirps at night
Oboti, L.; Pedraja, F.; Ritter, M.; Lohse, M.; Klette, L.; Krahe, R.
10.1101/2022.12.29.522225 — animal behavior and cognition — Posted on 2024-11-11
3327 A Contribution To The Anatomy Of Two Rare Cetacean Species: The Hourglass Dolphin (Lagenorhynchus cruciger) And The Spectacled Porpoise (Phocoena dioptrica)
Graic, J.-M.; Gerussi, T.; Cozzi, B.; Kot, B. C. W.; Boys, R. M.; Perrott, M.; Fleury, K.; Burns, E.; Webster, T.; Betty, E.; Howarth, O.; Loch, C.; White, S.; Dawson, S.; Rayment, W.; Hunter, S.; Cole, R.; Cox, D.; Young, M.; Roberts, J.; Waterhouse, T.; Smith, R.; Ogle, M.; Fyfe, J.; Hendriks, H.; van Helden, A.; Johnstone, M.; Stewart, R. O.; Fordyce, R. E.; Stockin, K. A.
10.1101/2024.11.06.622215 — evolutionary biology — Posted on 2024-11-11
3329 Nanomechanics of cell-derived matrices as a functional read-out in Collagen VI-related Congenital Muscular Dystrophies
White, T.; Lopez-Marquez, A.; Badosa, C.; Jimenez-Mallebrera, C.; Samitier, J.; Giannotti, M. I.; Lagunas, A.
10.1101/2024.09.13.612824 — biophysics — Posted on 2024-11-11
3330 PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data
de Visser, M. C.; Ploeg, C. v. d.; Cvijanovic, M.; Vucic, T.; Theodoropoulos, A.; Wielstra, B.
10.1101/2024.10.25.620064 — bioengineering — Posted on 2024-11-11
3332 NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts)
de Visser, M. C.; France, J.; McCartney-Melstad, E.; Bucciarelli, G. M.; Theodoropoulos, A.; Shaffer, H. B.; Wielstra, B.
10.1101/2024.10.25.620290 — genomics — Posted on 2024-11-11
3333 Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping
de Visser, M. C.; Meilink, W. R. M.; Theodoropoulos, A.; Fahrbach, M.; Wielstra, B.
10.1101/2024.10.25.620256 — molecular biology — Posted on 2024-11-11
3334 Identification and Characterization of Archaeal Pseudomurein Biosynthesis Genes through Pangenomics
Lupo, V.; Roomans, C.; Royen, E.; Ongena, L.; Jacquemin, O.; Mullender, C.; Kerff, F.; Baurain, D.
10.1101/2024.11.07.622503 — microbiology — Posted on 2024-11-11
3335 Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum
Ejdrup, A. L.; Dreyer, J. K.; Lycas, M. D.; Jorgensen, S. H.; Robbins, T. W.; Dalley, J. W.; Herborg, F.; Gether, U.
10.1101/2024.07.03.601861 — neuroscience — Posted on 2024-11-11
3338 Smart Distributed Data Factory: Volunteer Computing Platform for Active Learning-Driven Molecular Data Acquisition
Ghukasyan, T.; Altunyan, V.; Bughdaryan, A.; Aghajanyan, T.; Smbatyan, K.; Papoian, G. A.; Petrosyan, G.
10.1101/2024.10.22.619651 — biophysics — Posted on 2024-11-11
3342 Instantaneous change in hyphal diameter in basidiomycete fungi
Mazheika, I. S.; Voronko, O. V.; Kolomiets, O. L.; Kamzolkina, O. V.
10.1101/2024.02.12.579893 — cell biology — Posted on 2024-11-11
3349 Structure of the TXNL1-bound proteasome
Gao, J.; Nardone, C.; Yip, M. C.; Chino, H.; Gu, X.; Mirman, Z.; Rale, M. J.; Paulo, J. A.; Elledge, S. J.; Shao, S.
10.1101/2024.11.08.622741 — cell biology — Posted on 2024-11-10
3350 A negative feedback loop between small GTPase Rap1 and mammalian tumor suppressor homolog KrsB regulates cell-substrate adhesion in Dictyostelium
Artemenko, Y.; Niu, G.; Arnold, M. E.; Roberts, K. E.; Fernandez, B. N.; Flores, T.; McClave, H. D.; Paestella, M.; Borleis, J.; Devreotes, P. N.
10.1101/2024.11.07.622562 — cell biology — Posted on 2024-11-10
3351 M1-linked Ubiquitination by LUBAC Regulates AMPK Activity and the Response to Energetic Stress
Elbaek, C. R.; Jahan, A. S.; Cuenco, J.; Dahlstrom, A. M.; Aalto, A. L.; Rizk, J.; Hawley, S. A.; Franks, S. N. J.; Stumpe, M.; Kolapalli, S. P.; Hildebrandt, X.; Frueh, A. E.; Nielsen, K.; Priesmann, D.; Koch, J.; Deichmann, M.; Gullmets, J.; Verboom, L.; van Loo, G.; Peltzer, N.; Frankel, L. B.; Gyrd-Hansen, M.; Dengjel, J.; Ryan, B. J.; Hardie, D. G.; Meinander, A.; Sakamoto, K.; Damgaard, R. B.
10.1101/2024.11.08.622598 — cell biology — Posted on 2024-11-10
3353 Cytoplasmic lncRNAs nucleate signalling pathways to define metastable state dynamics and determine phenotypic output
PORTAL, M. M.; Shlyakhtina, Y.; Bloechl, B.; Moran, K. L.; Maslakova, A.; Carragher, N.; Munro, A. F.
10.1101/2024.11.08.622637 — cell biology — Posted on 2024-11-10
3354 Hydrocarbon effects on cell survival and antioxidant system of breast tumorigenic and non-tumorigenic cells.
Mardirosian, M. N.; Lasagna, M.; Nunez, M.; Galarza, T.; Espert, N.; Venturino, A.; Cocca, C.
10.1101/2024.11.08.622500 — cell biology — Posted on 2024-11-10
3355 All-Optical Multimodal Mapping of Single Cell Type-Specific Metabolic Activities via REDCAT
Shi, L.; Li, Y.; Zhang, Z.; Enninful, A.; Nam, J.; Qin, X.; Villazon, J.; Fazard, N.; Fung, A. A.; Xu, M. L.; Jang, H.; Zhang, N. R.; Fan, R.; Ma, Z.
10.1101/2024.11.07.622511 — cell biology — Posted on 2024-11-10
3356 Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of Osteoarthritis
Al_Jezani, N.; Affan, A.; Leonard, C.; Das, N.; Almeida, L. G.; Young, D.; Masson, A. O.; Dufour, A.; Salo, P.; Railton, P.; Powell, J. N.; Krawetz, R. J.
10.1101/2024.11.10.622893 — cell biology — Posted on 2024-11-10
3357 Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal
Vial, T.; Lopez-Maestre, H.; Couderc, E.; Pinaud, S.; Howick, V.; Akorli, J.; Lawniczak, M.; Marti, G.; Merkling, S. H.
10.1101/2024.11.08.622039 — cell biology — Posted on 2024-11-11
3358 Image-based DNA Sequencing Encoding for Detecting Low-Mosaicism Somatic Mobile Element Insertions
Tan, M.; Lin, Z.; Chen, Z.; Park, J.; He, Z.; Zhou, H.; Lee, E. A.; Gao, Z.; Zhu, X.
10.1101/2024.11.07.619809 — genomics — Posted on 2024-11-11
3363 Comprehensive protease specificity profiling
Zhu, B.; Lane, M. D.; Baller, J. A.; Jagtap, P. D.; Griffin, T. J.; Seelig, B.
10.1101/2024.11.06.622033 — biochemistry — Posted on 2024-11-10
3368 Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-viral hsa-miR-132 Processing
Imig, J.; Schloesser, V.; Lightfoot, H. L.; Leemann, C.; Bejoy, A. M.; Tiwari, S.; Schlosshauer, J. L.; Vongrad, V.; Brunschweiger, A.; Hall, J.; Metzner, K. J.
10.1101/2024.11.10.622865 — molecular biology — Posted on 2024-11-10
3370 ComFB, a new widespread family of c-di-NMP receptor proteins
Samir, S.; Elshereef, A. A.; Alva, V.; Hahn, J.; Dubnau, D.; Galperin, M. Y.; Selim, K. A.
10.1101/2024.11.10.622515 — microbiology — Posted on 2024-11-10
3371 Genomic Diversity in Porphyromonas: Evidence of Porphyromonas catoniae Commensality in Lungs
VELO-SUAREZ, L.; MOALIC, Y.; GUILLOUX, C.-A.; AME, J.; LAMOUREUX, C.; GOURIOU, S.; LE BERRE, R.; BEAURUELLE, C.; HERY-ARNAUD, G.
10.1101/2024.11.09.622806 — microbiology — Posted on 2024-11-10
3372 Oceanic photosynthesis is directly affected by cyanophage NblA proteins
Beja, O.; Nadel, O.; Hanna, R.; Rozenberg, A.; Shitrit, D.; Tahan, R.; Pekarsky, I.; Kleifeld, O.; Lindell, D.
10.1101/2024.11.10.622831 — microbiology — Posted on 2024-11-10
3375 De novo design of triosephosphate isomerases using generative language models
Romero-Romero, S.; Braun, A. E.; Kossendey, T.; Ferruz, N.; Schmidt, S.; Höcker, B.
10.1101/2024.11.10.622869 — biochemistry — Posted on 2024-11-10
3377 Resuscitation-promoting factor (Rpf) terminates dormancy among diverse soil bacteria
Lennon, J. T.; Lehmkuhl, B. K.; Chen, L.; Illingworth, M.; Kuo, V.; Muscarella, M. E.
10.1101/2024.11.10.622857 — microbiology — Posted on 2024-11-10
3378 Pfs230 Domain 12 is a potent malaria transmission-blocking vaccine candidate
Inklaar, M. R.; de Jong, R. M.; Da, D. F. R.; Hubregtse, L.; Meijer, M.; Teelen, K.; van de Vegte-Bolmer, M.; van Gemert, G.-J.; Stoter, R.; Nagaoka, H.; Tsuboi, T.; Takashima, E.; Spruijt, C. G.; Vermeulen, M.; Dabire, R. K.; Arinaitwe, E.; Cohuet, A.; Bousema, T.; Jore, M. M.
10.1101/2024.11.09.622785 — immunology — Posted on 2024-11-10
3379 Sacrificing Adaptability for Functionality: The Ivory Tower of Macular Muller Cells
Zhang, T.; Jin, K.; Zeng, S.; Yang, P.; Zhu, M.; Zhang, J.; Chen, Y.; Lee, S.; Yam, M.; Zeng, Y.; Lu, X.; Loo, L.; Neely, G. G.; Chang, A.; Zhou, F.; Du, J.; Fan, X.; Zhu, L.; Gillies, M.
10.1101/2024.04.28.590478 — neuroscience — Posted on 2024-11-10
3380 Predicting binding events in very flexible, allosteric, multi-domain proteins
Basciu, A.; Athar, M.; Kurt, H.; Neville, C.; Malloci, G.; Muredda, F.; Bosin, A.; Ruggerone, P.; Bonvin, A.; Vargiu, A. V.
10.1101/2024.06.02.597018 — biophysics — Posted on 2024-11-10
3381 Celldetective: an AI-enhanced image analysis toolfor unraveling dynamic cell interactions
Torro, R.; Diaz Bello, B.; El Arawi, D.; Dervanova, K.; Ammer, L.; Dupuy, F.; Chames, P.; Sengupta, K.; Limozin, L.
10.1101/2024.03.15.585250 — bioinformatics — Posted on 2024-11-10
3383 Multiplex PCR with Nanopore Sequencing for Sequence-Based Detection of Four Tilapia Pathogens
Delamare-Deboutteville, J.; Meetmetta, W.; Pimsannil, K.; Gan, H. M.; Khor Li Imm, L.; Chadag Mohan, V.; Dong, H. T.; Senapin, S.
10.1101/2023.05.13.540096 — genomics — Posted on 2024-11-10
3384 Temporal loss of genome-wide and immunogenetic diversity in a near-extinct parrot
Silver, L. W.; Farquharson, K. A.; Peel, E.; Gilbert, M. T. P.; Belov, K.; Morales, H. E.; Hogg, C. J.
10.1101/2024.11.10.622863 — genomics — Posted on 2024-11-10
3385 Clathrin-independent endocytosis of Human Papillomaviruses is facilitated by actin nucleation promoting factor WASH
Brinkert, P.; Krebs, L.; Samperio Ventayol, P.; Greune, L.; Bannach, C.; Bucher, D.; Kollasser, J.; Dersch, P.; Boulant, S.; Stradal, T. E. B.; Schelhaas, M.
10.1101/2021.06.18.448076 — cell biology — Posted on 2024-11-10
3386 Intrinsic Diversity In Primary Cilia Revealed Through Spatial Proteomics
Hansen, J. N.; Sun, H.; Kahnert, K.; Westenius, E.; Johannesson, A.; Tzavlaki, K.; Winsnes, C.; Pohjahnen, E.; Fall, J.; Navarro, F. B.; Backstrom, A.; Lindskog, C.; Johansson, F.; von Feilitzen, K.; Vega, A. D.; Uhlen, M.; Casals, A. M.; Mahdessian, D.; Lindstrand, A.; Axelsson, U.; Lundberg, E.
10.1101/2024.10.20.619273 — cell biology — Posted on 2024-11-10
3387 In vivo functional profiling and structural characterisation of the human Glp1r A316T variant
El Eid, L.; Deane-Alder, K.; Rujan, R.-M.; Mariam, Z.; Oqua, A. I.; Manchanda, Y.; Belousoff, M. J.; Bernardino de la Serna, J.; Sloop, K. W.; Rutter, G. A.; Montoya, A.; Withers, D. J.; Millership, S.; Bouzakri, K.; Jones, B.; Reynolds, C. A.; Sexton, P. M.; Wootten, D.; Deganutti, G.; Tomas, A.
10.1101/2024.10.19.619191 — cell biology — Posted on 2024-11-10
3388 Systematic analysis of nonsense variants uncovers peptide release rate as a novel modifier of nonsense-mediated mRNA decay
Kolakada, D.; Fu, R.; Biziaev, N.; Shuvalov, A.; Lore, M.; Campbell, A. E.; Cortazar, M. A.; Sajek, M. P.; Hesselberth, J. R.; Mukherjee, N.; Alkalaeva, E.; Akdemir, Z. H. C.; Jagannathan, S.
10.1101/2024.01.10.575080 — molecular biology — Posted on 2024-11-10
3391 A CRISPR-Cas9 assisted analysis of single-cell microbiomes for identifying rare bacterial taxa in phycospheres of diatoms
Giesler, J. K.; Mock, T.; Harder, T.; John, U.; Wohlrab, S.; Neuhaus, S.; Kuehne, N.; Belshaw, N.; Schulte-Hillen, R. L.
10.1101/2024.11.10.622248 — microbiology — Posted on 2024-11-10
3392 Seasonal patterns in b-vitamins and cobalamin co-limitation in the Northwest Atlantic
Bannon, C. C.; White, P. L.; Rowland, E.; More, K. J.; Gleason, A.; Roberts, M.; Devred, E.; Beazley, L.; LaRoche, J.; Bertrand, E. M.
10.1101/2024.11.10.622835 — microbiology — Posted on 2024-11-10
3394 Stroke and Motor Recovery are Associated with Regional and Age-Specific Changes in Periodic and Aperiodic Cortical Activity
Albertson, A. J.; Landsness, E. C.; Eisfelder, M.; Young, B. M.; Judge, B.; Brier, M. R.; Euler, M. J.; Cramer, S. C.; Lee, J.-M.; Lohse, K. R.
10.1101/2024.11.07.622359 — neuroscience — Posted on 2024-11-10
3395 Genetic variance in the murine defensin locus modulates glucose homeostasis
Masson, S. W. W.; Simpson, R. C.; Cutler, H. B.; Carlos, P. W.; Marian, O. C.; Potter, M.; Madsen, S.; Cooke, K. C.; Craw, N. R.; Fuller, O. K.; Harney, D. J.; Larance, M.; Cooney, G. J.; Morahan, G.; Shanahan, E. R.; Hodgkins, C.; Payne, R. J.; Stöckli, J.; James, D. E.
10.1101/2024.07.25.605202 — systems biology — Posted on 2024-11-10
3397 Morpho-molecular features of Epithelial Mesenchymal Transition associate with clinical outcome in patients with rectal cancer
Gwerder, M.; Demir, C. S.; Williams, H. L.; Lugli, A.; Martinez, C. G.; Kowal, j.; Khan, A.; Kirchner, P.; Koessler, T.; Berger, M. D.; Weigert, M.; Zlobec, I.
10.1101/2024.11.07.622481 — cancer biology — Posted on 2024-11-10
3402 Geographic-specific Diversification of Vaginal Microbiota in China
Yang, H.; Liu, Y.; Liu, Z.; Zhou, C.; Hu, L.; He, J.; Lv, L.; Zhou, Z.; Zhu, L.
10.1101/2024.11.08.622683 — microbiology — Posted on 2024-11-10
3405 Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn's Disease
Cao, S.; Nguyen, K. M.; Ma, K.; Yao, X.; Liu, T.-C.; Ayoub, M.; Devi, J.; Liu, Y.; Smith, R.; Silviera, M.; Hunt, S. R.; Wise, P. E.; Mutch, M. G.; Glasgow, S. C.; Chapman, W. C.; Cowan, M.; Ciorba, M. A.; Colonna, M.; Deepak, P.
10.1101/2024.11.08.620717 — systems biology — Posted on 2024-11-10
3406 TiFM2.0 - Versatile mechanical measurement and actuation in live embryos
Hernandez-Rodriguez, A. R.; Lan, Y.; Ji, F.; McLaren, S. B. P.; Vidigueira, J. M. N.; Li, R.; Dai, Y.; Holmes, E.; Moon, L. D.; Balasubramaniam, L.; Xiong, F.
10.1101/2024.11.10.622720 — developmental biology — Posted on 2024-11-10
3412 MatP local enrichment delays segregation independently of tetramer formation and septal anchoring in Vibrio cholerae
Espinosa, E.; Challita, J.; Desfontaines, J.-M.; Possoz, C.; Val, M.-E.; Mazel, D.; Marbouty, M.; Koszul, R.; Galli, E.; Barre, F. X.
10.1101/2024.02.08.578905 — microbiology — Posted on 2024-11-10
3413 Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in Escherichia coli
Sotomayor, B.; Donahue, T. C.; Mahajan, S. P.; Taw, M. N.; Hulbert, S. W.; Bidstrup, E. J.; Owitipana, D. N.; Pang, A.; Yang, X.; Ghosal, S.; Alabi, C. A.; Azadi, P.; Gray, J. J.; Jewett, M. C.; Wang, L.-X.; DeLisa, M. P.
10.1101/2024.08.12.607630 — synthetic biology — Posted on 2024-11-10
3414 Induction by caterpillars of stored and emitted volatiles in terpene chemotypes from populations of wild cotton (Gossypium hirsutum)
Mamin, M.; Clancy, M. V.; Fluckiger, G.; Quijano-Medina, T.; Perez-Nino, B.; Abdala-Roberts, L.; Turlings, T.; Bustos-Segura, C.
10.1101/2024.04.17.589906 — plant biology — Posted on 2024-11-10
3416 Bio-engineering a common probiotic to exploit colonic inflammation promotes reliable efficacy in translational models of colitis
Verdugo Meza, A.; Gill, S. K.; Godovannyi, A.; Adur, M. K.; Barnett, J. A.; Estaki, M.; Ye, J.; Haskey, N.; Mehain, H.; Josephson, J. K.; Ishida, R.; Ghesquiere, C.; Sly, L. M.; Gibson, D. L.
10.1101/2024.10.08.617317 — microbiology — Posted on 2024-11-10
3418 Spatio-temporal diversity and genetic architecture of pyrantel resistance in Cylicocyclus nassatus, the most abundant horse parasite
Salle, G.; Courtot, E.; Cabau, C.; Parrinello, H.; Serreau, D.; Reigner, F.; Gesbert, A.; Jacquinot, L.; Lenhof, O.; Aime, A.; Picandet, V.; Kuzmina, T.; Holovachov, O.; Bellaw, J.; Nielsen, M. K.; von Samson-Himmelstjerna, G.; Valiere, S.; Gislard, M.; Lluch, J.; Kuchly, C.; Klopp, C.
10.1101/2023.07.19.549683 — genomics — Posted on 2024-11-10
3419 A consensus variant-to-function score to functionally prioritize variants for disease
Fabiha, T.; Evergreen, I.; Kundu, S.; Pampari, A.; Abramov, S.; Boytsov, A.; Strouse, K.; Dura, K.; Fang, W.; Kerner, G.; Butts, J.; Ali, T.; Gschwind, A.; Mualim, K. S.; Moore, J. E.; Weng, Z.; Ulirsch, J.; Ji, H. E.; Vierstra, J.; Reddy, T. E.; Montgomery, S. B.; Engreitz, J.; Kundaje, A.; Tewhey, R.; Price, A.; Dey, K.
10.1101/2024.11.07.622307 — genetics — Posted on 2024-11-10
3422 Integration of Unpaired and Heterogeneous Clinical Flow Cytometry Data
Phuycharoen, M.; Kaestele, V.; Williams, T.; Lin, L.; Hussell, T.; Grainger, J.; Rattray, M.
10.1101/2023.12.18.572157 — bioinformatics — Posted on 2024-11-09
3424 An Autoinhibited Conformation of the DnaB-Replicative Helicase - phage {lambda}P Loader Complex
Brown, D.; Shatarupa, A.; Olinares, P. D.; Chase, J. D.; Isiorho, E.; Chait, B.; Jeruzalmi, D.
10.1101/2022.12.30.522210 — biochemistry — Posted on 2024-11-09
3425 Rapid speciation in the holopelagic ctenophore Mnemiopsis following glacial recession
Ketchum, R. N.; Smith, E. G.; Toledo, L.; Leach, W. B.; Padillo-Anthemides, N.; Baxevanis, A. D.; Reitzel, A. M.; Ryan, J. F.
10.1101/2024.10.10.617593 — evolutionary biology — Posted on 2024-11-09
3426 RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing
Wu, T.; Chen, Z.; Zhang, Z.; Zhou, X.; Gu, Y.; Dinenno, F. A.; Chen, J.
10.1101/2024.11.07.622565 — developmental biology — Posted on 2024-11-09
3427 MMP21 behaves as a fluid flow transported morphogen to impart laterality during development
Ott, T.; Brugger, A.; Szenker-Ravi, E.; Kurrle, Y.; Aberle, O.; Tisler, M.; Blum, M.; Whalen, S.; Bouvagnet, P.; Reversade, B.; Schweickert, A.
10.1101/2024.10.13.618030 — developmental biology — Posted on 2024-11-09
3429 A bacterial cell wall repair and modification system to resist host antibacterial factors
Burnier, J.; Gallay, C.; Bruce, K.; Bjanes, E.; Martin, L.; Jim, K. K.; Tsui, T.; Cremers, A.; Mignolet, J.; Vollmer, D.; Biboy, J.; Nizet, V.; Vollmer, W.; Winkler, M. E.; Veening, J.-W.
10.1101/2024.11.08.622053 — microbiology — Posted on 2024-11-09
3430 Carotenoid pigments enhance rhodopsin-mediated phototrophy by light-harvesting and photocycle-accelerating
Fujiwara, T.; Hosaka, T.; Hasegawa-Takano, M.; Nishimura, Y.; Tominaga, K.; Mori, K.; Nishino, S.; Takahashi, Y.; Uchikubo-Kamo, T.; Hanada, K.; Maoka, T.; Takaichi, S.; Inoue, K.; Shirouzu, M.; Yoshizawa, S.
10.1101/2024.11.08.622755 — microbiology — Posted on 2024-11-09
3431 Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein-Protein Interactions Using Phage Display
Wang, S.; Faucher, F. F.; Bertolini, M.; Kim, H.; Yu, B.; Cao, L.; Roeltgen, K.; Lovell, S.; Shanker, V.; Boyd, S. D.; Wang, L.; Bartenschlager, R.; Bogyo, M.
10.1101/2024.11.08.622749 — microbiology — Posted on 2024-11-09
3432 Contrasted viral communities between Aedes albopictus and Culex quinquefasciatus in La Reunion Island
Francois, S.; Antoine-Lorquin, A.; Mutuel, D.; Makoundou, P.; Perriat-Sanguinet, M.; Unal, S.; Sobry, H.; Gosselin-Grenet, A.-S.; Ogliastro, M.; Sicard, M.; Weill, M.; Atyame, C.; Boëte, C.
10.1101/2024.11.08.622592 — microbiology — Posted on 2024-11-09
3433 Bidirectional Peptide Conformation Prediction for MHC Class II using PANDORA
Rademaker, D. T.; Parizi, F. M.; van Vreeswijk, M.; Eerden, S.; Marzella, D.; Xue, L.
10.1101/2024.11.04.621877 — immunology — Posted on 2024-11-09
3436 Phenylacetic acid metabolism in land plants: novel pathways and metabolites
Hladik, P.; Brunoni, F.; Zukauskaite, A.; Zatloukal, M.; Belicek, J.; Kopecny, D.; Briozzo, P.; Ferchaud, N.; Novak, O.; Pencik, A.
10.1101/2024.11.06.622264 — plant biology — Posted on 2024-11-09
3438 Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions
Langstein-Skora, I.; Schmid, A.; Huth, F.; Shabani, D.; Spechtenhauser, L.; Likhodeeva, M.; Kunert, F.; Metzner, F. J.; Emenecker, R. J.; Richardson, M. O. G.; Aftab, W.; Goetz, M. J.; Payer, S. K.; Pietrantoni, N.; Sjenicic, V.; Ravichandran, S. K.; Bartke, T.; Hopfner, K.-P.; Gerland, U.; Korber, P.; Holehouse, A. S.
10.1101/2022.02.10.480018 — biophysics — Posted on 2024-11-09
3440 Decoding Spatial Tissue Architecture: A Scalable Bayesian Topic Model for Multiplexed Imaging Analysis
Peng, X.; Smithy, J. W.; Yosofvand, M.; Kostrzewa, C. E.; Bleile, M.; Ehrich, F. D.; Lee, J.; Postow, M. A.; Callahan, M. K.; Panageas, K. S.; Shen, R.
10.1101/2024.10.08.617293 — bioinformatics — Posted on 2024-11-09
3442 A consensus variant-to-function score to functionally prioritize variants for disease
Fabiha, T.; Raine, I.; Kundu, S.; Pampari, A.; Abramov, S.; Boytsov, A.; Strouse, K.; Dura, K.; Fang, W.; Kerner, G.; Butts, J.; Ali, T.; Gschwind, A.; Mualim, K. S.; Moore, J. E.; Weng, Z.; Ulirsch, J.; Ji, H. E.; Vierstra, J.; Reddy, T. E.; Montgomery, S. B.; Engreitz, J.; Kundaje, A.; Tewhey, R.; Price, A.; Dey, K.
10.1101/2024.11.07.622307 — genetics — Posted on 2024-11-09
3446 Perilipin 5 Phosphorylation is Dispensable for Upregulation of Hepatic Lipid Metabolism Genes upon Fasting but Required for Insulin Receptor Substrate 2 Expression in Male Mice
Bovee, C.; Grandgenett, R.; Trevino, M.; Dutta, S.; Peachee, S.; Kopriva, S.; Haider, F.; Liu, S.; Bhardwaj, G.; Penniman, C.; O'Neill, B.; Imai, Y.
10.1101/2024.11.09.622792 — molecular biology — Posted on 2024-11-09
3448 Isolation, Characterization, and Identification of Nitrogen Fixing Bacteria from Rhizosphere of Sonneratia apetala Collected from Sundarbans
Rimi, A. A.; Roshnee, F. I.; Shuvro, K.; Tasin, M. H. R.; Akter, R.; Islam, M. E.; Islam, K. M. D.; Rahman, S. M. M.; Billah, M. M.
10.1101/2024.11.09.622791 — microbiology — Posted on 2024-11-09
3449 Evaluating metagenomic analyses for undercharacterized environments: what's needed to light up the microbial dark matter?
Nickols, W. A.; McIver, L. J.; Walsh, A.; Zhang, Y.; Nearing, J.; Asnicar, F.; Nguyen, L.; Hartmann, E. M.; Franzosa, E. A.; Huttenhower, C.; Thompson, K. N.
10.1101/2024.11.08.622677 — microbiology — Posted on 2024-11-09
3450 Microbial Differences Accurately Identifies Global SERT KO Phenotype in Mice
Leitman, M.; Katza, W.; Zhang, D.; Pawar, S.; Shera, S.; Hernandez, L.; Dong, T.
10.1101/2024.11.08.622711 — microbiology — Posted on 2024-11-09
3452 Phenotypic high-throughput screening identifies modulators of gut microbial choline metabolism
Woo, A. Y. M.; Sandoval-Espinola, W. J.; Bollenbach, M.; Wong, A.; Sakanaka-Yokoyama, M.; Zhang, Q.; Nieto, V.; Rey, F. E.; Balskus, E. P.
10.1101/2024.11.08.621386 — microbiology — Posted on 2024-11-09
3453 Pathogenesis and immune response to respiratory coronaviruses in their natural porcine host
Sedaghat-Rostami, E.; Carr, B. V.; Yang, L.; Keep, S.; Lean, F. Z. X.; Atkinson, I.; Fones, A.; Paudyal, B.; Kirk, J.; Vatzia, E.; Gubbins, S.; Bickerton, E.; Briggs, E.; Nunez, A. Z. X.; MacNee, A.; Moffat, K.; Freimanis, G.; Rollier, C.; Muir, A.; Richard, A. C.; Angelopoulos, N.; Gerner, W.; Tchilian, E.
10.1101/2024.11.08.622602 — immunology — Posted on 2024-11-09
3458 Language model generates cis-regulatory elements across prokaryotes
Xia, Y.; Sun, J.; Du, X.; Liang, Z.; Shi, W.; Guo, S.; Huo, Y.-X.
10.1101/2024.11.07.622410 — bioinformatics — Posted on 2024-11-09
3460 DnaB and DciA: Mechanisms of Helicase Loading and Translocation on ssDNA
Gao, N.; Mazzoletti, D.; Peng, A.; Olinares, P. D. B.; Morrone, C.; Garavaglia, A.; Gouda, N.; Tsoy, S.; Mendoza, A.; Chowdhury, A.; Cerullo, A. R.; Bhavsar, H.; Rossi, F.; Rizzi, M.; Chait, B.; Miggiano, R.; Jeruzalmi, D.
10.1101/2024.11.09.622779 — biochemistry — Posted on 2024-11-09
3462 Comprehensive benchmarking of tools for nanopore-based detection of DNA methylation
Kulkarni, O.; Mathew, R. J.; Zaveri, L.; Jana, R.; Singh, N. K.; Ara, S.; Tallapaka, K. B.; Sowpati, D. T.
10.1101/2024.11.09.622763 — genomics — Posted on 2024-11-09
3463 Genetic Basis, Quantitative Nature, and Functional Relevance of Evolutionarily Conserved DNA Methylation
Dong, Z.; Schaffner, S.; Fu, M.; Whitehead, J.; MacIsaac, J. L.; Rehkopf, D. H.; Boyce, W. T.; Rosero-Bixby, L.; Quintana-Murci, L.; Patin, E.; Miller, G. E.; Korthauer, K.; Kobor, M. S.
10.1101/2024.11.07.622474 — genetics — Posted on 2024-11-09
3464 Drospondin, a novel glial-secreted glycoprotein, controls the development and function of the Drosophila nervous system
Rojo-Cortes, F.; Roa-Siegfried, C.; Fuenzalida-Uribe, N.; Amado-Hinojosa, P.; Gonzalez-Ramirez, M.-C.; Almonacid-Torres, I.; Birman, S.; Goodman, L. D.; Kanka, O.; Oliva, C.; Marzolo, M.-P.; Campusano, J. M.
10.1101/2024.11.08.622737 — developmental biology — Posted on 2024-11-09
3465 Drugs Commonly Used in Fungal Infection Risk Conditions Promote Drug Tolerance or Resistance in Candida albicans
Obermeier, M.; Esparza Mora, M. A.; Heese, O.; Cohen, N.; Varma, S. J.; Tober-Lau, P.; Hartl, J.; Kurth, F.; Berman, J.; Ralser, M.
10.1101/2024.11.09.622705 — microbiology — Posted on 2024-11-09
3473 The development of aperiodic neural activity in the human brain
Cross, Z. R.; Gray, S. M.; Dede, A. J. O.; Rivera, Y. M.; Yin, Q.; Vahidi, P.; Rau, E. M. B.; Cyr, C.; Holubecki, A. M.; Asano, E.; Lin, J. J.; McManus, O. K.; Sattar, S.; Saez, I.; Girgis, F.; King-Stephens, D.; Weber, P. B.; Laxer, K. D.; Schuele, S. U.; Rosenow, J. M.; Wu, J. Y.; Kam, S. K.; Raskin, J. S.; Chang, E. F.; Shaikhouni, A.; Brunner, P.; Roland, J. L.; Braga, R. M.; Knight, R. T.; Ofen, N.; Johnson, E. L.
10.1101/2024.11.08.622714 — neuroscience — Posted on 2024-11-09
3476 Encoding opposing valences through frequency-dependent transmitter switching in single peptidergic neurons
Kim, D.-I.; Kang, S. J.; Jhang, J.; Jo, Y. S.; Park, S.; Ye, M.; Pyeon, G. H.; Im, G.-H.; Kim, S.-G.; Han, S.
10.1101/2024.11.09.622790 — neuroscience — Posted on 2024-11-09
3477 Projections between the globus pallidus externa and cortex span motor and non-motor regions
Ferenczi, E. A.; Wang, W.; Biswas, A.; Pottala, T.; Dong, Y.; Chan, A. K.; Albanese, M. A.; Sohur, R. S.; Jia, T.; Mastro, K. J.; Sabatini, B. L.
10.1101/2024.11.08.622712 — neuroscience — Posted on 2024-11-09
3480 Mitochondrial direct repeat reduction as a strategy for enhancing human longevity: the case of the common repeat
Shamanskiy, V. A.; Gunbin, K. V.; Tretiakov, E. O.; Mazunin, I. O.; Skripskaya, V.; Mihailova, A. A.; Mikhailova, A. G.; Ree, N.; Timonina, V.; Knorre, D.; Kunz, W. S.; Okada, Y.; Fiorellino, N.; Reymond, A.; Bazykin, G. A.; Fellay, J.; Tanaka, M.; Khrapko, K.; Popadin, K.
10.1101/2024.09.02.610808 — genetics — Posted on 2024-11-09
3482 Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation
van der Heijden, E. S.; Nasvall, K.; Seixas, F. A.; Beserra Nobre, C. E.; Campos D Maia, A.; Salazar-Carrion, P. A.; Walker, J. M.; Szczerbowski, D.; Schulz, S.; Warren, I. A.; Gavilanes Cordova, K. G.; Sanchez-Carvajal, M. J.; Chandi, F.; Arias-Cruz, A. P.; Rueda-Munoz, N.; Salazar, C.; Dasmahapatra, K. K.; Montgomery, S. H.; McClure, M.; Absolon, D. E.; Mathers, T. C.; Santos, C. A.; McCarthy, S.; Wood, J.; Lamas, G.; Bacquet, C.; Freitas, A. V.; Willmott, K. R.; Jiggins, C. D.; Elias, M.; Meier, J. I.
10.1101/2024.07.07.602206 — evolutionary biology — Posted on 2024-11-09
3485 Small molecule oxybutynin rescues proliferative capacity of complex III-defective MPCs
Qu, Y.; Edwards, K.; Li, M.; Liu, Y.; Tsai, P.-Y.; Cheng, C.; Blum, J.; Acor, N.; Oshoe, T.; Rooney, K.; Walter, C.; Thirumlaikumar, V. P.; Thalacker-Mercer, A.; Skirycz, A.; Barrow, J.
10.1101/2024.11.08.622694 — cell biology — Posted on 2024-11-09
3486 Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex
Sokpor, G.; Ulmke, P. A.; Nguyen, H. D.; Pham, L.; Kakani, P.; Chu, V. T.; Arnold, S. J.; Brand-Saberi, B.; Nguyen, H. P.; Tuoc, T.
10.1101/2024.11.05.621758 — neuroscience — Posted on 2024-11-09
3488 HistoGWAS: An AI-enabled Framework for Automated Genetic Analysis of Tissue Phenotypes in Histology Cohorts
Chaudhary, S.; Voigts, A.; Bereket, M.; Albert, M.; Schwamborn, K.; Zeggini, E.; Casale, F. P.
10.1101/2024.06.09.597752 — genetics — Posted on 2024-11-09
3489 A multivalent adaptor mechanism drives the nuclear import of proteasomes
Brunner, H. L.; Kalis, R. W.; Grundmann, L.; Hodakova, Z.; Koskova, Z.; Grishkovskaya, I.; de Almeida, M.; Hinterndorfer, M.; Hoefflin, S.; Andersch, F.; Kotisch, H.; Dickmanns, A.; Cuylen-Haering, S.; Zuber, J.; Haselbach, D.
10.1101/2024.11.08.622636 — molecular biology — Posted on 2024-11-09
3496 Cerebellar-Prefrontal Connectivity Predicts Negative Symptom Severity Across the Psychosis Spectrum
Yarrell, S. A.; Blyth, S. H.; Rogers, B. P.; Huang, A.; Moussa-Tooks, A.; Woodward, N. D.; Heckers, S.; Brady, R.; Ward, H. B.
10.1101/2024.11.07.622549 — neuroscience — Posted on 2024-11-08
3497 A "torn bag mechanism" of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)
Visnovitz, T.; Lenzinger, D.; Koncz, A.; Vizi, P. M.; Barkai, T.; Vukman, K. V.; Galinsoga, A.; Nemeth, K.; Fletcher, K.; Komlosi, Z. I.; Cserep, C.; Denes, A.; Lorincz, P.; Valcz, G.; BUZAS, E. I.
10.1101/2024.01.30.578035 — cell biology — Posted on 2024-11-08
3498 An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor
Wang, S.; Woods, E. C.; Jo, J.; Zhu, J.; Hansel-Harris, A.; Holcomb, M.; Pedowitz, N. J.; Upadhyay, T.; Bennett, J. M.; Fellner, M.; Park, K. W.; Zhang, A.; Valdez, T. A.; Forli, S.; Chan, A. I.; Cunningham, C.; Bogyo, M.
10.1101/2024.11.06.622387 — microbiology — Posted on 2024-11-08
3499 Three-dimensional single-cell transcriptome imaging of thick tissues
Fang, R.; Halpern, A. R.; Rahman, M. M.; Huang, Z.; Lei, Z.; Hell, S. J.; Dulac, C.; Zhuang, X.
10.1101/2023.07.21.550124 — neuroscience — Posted on 2024-11-08
3500 APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics
Ellis, D. S.; Watanabe, K.; Wilmanski, T.; Lustgarten, M. S.; Ardisson Korat, A. V.; Glusman, G.; Hadlock, J. J.; Fiehn, O.; Sebastiani, P.; Price, N. D.; Hood, L.; Magis, A. T.; Evans, S. J.; Pflieger, L.; Lovejoy, J. C.; Gibbons, S. M.; Funk, C. C.; Baloni, P.; Rappaport, N.
10.1101/2024.10.17.618322 — systems biology — Posted on 2024-11-08
3501 Large-Scale Computational Modeling of H5 Influenza Variants Against HA1-Neutralizing Antibodies
Ford, C. T.; Yasa, S.; Obeid, K.; Jaimes, R.; Tomezsko, P. J.; Guirales-Medrano, S.; White, R. A.; Janies, D.
10.1101/2024.07.14.603367 — bioinformatics — Posted on 2024-11-08
3502 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Patel, S. P.; Munugala, C.; Bloom, J. S.; Kruglyak, L.
10.1101/2023.12.07.570640 — genetics — Posted on 2024-11-08
3504 Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum
Lannan, J.; Floyd, C.; Xu, L. X.; Yan, C.; Marshall, W. F.; Vaikuntanathan, S.; Dinner, A. R.; Honts, J. E.; Bhamla, S.; Elting, M. W.
10.1101/2024.11.07.622534 — cell biology — Posted on 2024-11-08
3507 Cameroonian blackflies (Diptera: Simuliidae) harbour a plethora of (RNA) viruses
De Coninck, L.; Hadermann, A.; Ingletto, L.; Colebunders, R.; Njamnshi, K. G.; Njamnshi, A. K.; Mokili, J.; Siewe Fodjo, J. N.; Matthijnssens, J.
10.1101/2024.04.05.588247 — microbiology — Posted on 2024-11-08
3508 Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi
Dome, P. A.; Jeong, P.; Nam, G.; Jang, H.; Rivera, A.; Averette, A. F.; Park, E.; Liao, T.-C.; Ciofani, M.; Wu, J.; Chi, J.-T. A.; Venters, R. A.; Park, H.-J.; Steinbach, W. J.; Juvvadi, P. R.; Heitman, J.; Hong, J.
10.1101/2024.09.27.615491 — microbiology — Posted on 2024-11-08
3509 Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis
Nahas, K. L.; Connor, V.; Wijesinghe, K. J.; Barrow, H. G.; Dobbie, I. M.; Harkiolaki, M.; Graham, S. C.; Crump, C. M.
10.1101/2024.03.13.584906 — microbiology — Posted on 2024-11-08
3510 Unique T cell signatures associated with reduced Chlamydia trachomatis reinfection in a highly exposed cohort
Yount, K. S.; Chen, C.-J.; Kollipara, A.; Liu, C.; Mokashi, N. V.; Zheng, X.; Bagwell, C. B.; Poston, T. B.; Wiesenfeld, H. C.; Hillier, S. L.; O'Connell, C. M.; Stanley, N.; Darville, T.
10.1101/2023.08.02.551709 — immunology — Posted on 2024-11-08
3511 Generalizable gesture recognition usingmagnetomyography
Yun, R.; Csaky, R.; Dash, D.; Gerrard, I.; Gonzalez, G.; Kittle, E.; Taylor, D.; Soroushmojdehi, R.; Labanowski, D.; Deka, N.
10.1101/2024.09.30.615946 — neuroscience — Posted on 2024-11-08
3512 Role of Posterior Medial Thalamus in the Modulation of Striatal Circuitry and Choice Behavior
Yonk, A. J.; Linares-Garcia, I.; Pasternak, L.; Juliani, S. E.; Gradwell, M. A.; George, A. J.; Margolis, D. J.
10.1101/2024.03.21.586152 — neuroscience — Posted on 2024-11-08
3513 A developmental brain-wide screen identifies retrosplenial cortex as a key player in the emergence of persistent memory
Jin, B.; Gongwer, M. W.; Kearney, B. P.; Ohanian, L.; Holden-Wingate, L.; Le, B.; Darmawan, A.; Nakayama, Y.; Mora, S. A. R.; DeNardo, L. A.
10.1101/2024.01.07.574554 — neuroscience — Posted on 2024-11-08
3514 A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy
Rozak, M. W.; Mester, J. R.; Attarpour, A.; Dorr, A.; Patel, S.; Koletar, M.; Hill, M. E.; McLaurin, J.; Goubran, M.; Stefanovic, B.
10.1101/2024.01.24.577045 — neuroscience — Posted on 2024-11-08
3517 Primate thalamic nuclei select abstract rules and shape prefrontal dynamics
Phillips, J. M.; Afrasiabi, M.; Kambi, N. A.; Redinbaugh, M. J.; Steely, S.; Johnson, E. R.; Cheng, X.; Fayyad, M.; Mohanta, S.; Caris, A.; Mikell, C. B.; Mofakham, S.; Saalmann, Y. B.
10.1101/2024.03.13.584871 — neuroscience — Posted on 2024-11-08
3518 RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability
Provasek, V.; Bacolla, A.; Rangaswamy, S.; Mitra, J.; Kodavati, M.; Yusuf, I.; Malojirao, V.; Vasquez, V.; Britz, G. W.; Li, G.-M.; Xu, Z.; Mitra, S.; Garruto, R. M.; Tainer, J.; Hegde, M.
10.1101/2024.05.16.594552 — neuroscience — Posted on 2024-11-08
3520 High-Throughput Optimization of Paper-Based Cell-Free Biosensors
Garcia, D. C.; Davies, J. P.; Davidson, C. E.; Phillips, D. A.; Miklos, A. E.; Lux, M. W.
10.1101/2024.10.03.616554 — synthetic biology — Posted on 2024-11-08
3523 Rthoptera: standardised insect bioacoustics in R
Rivas, F.; Buzzetti, F. M.; Brizio, C.; Pijanowski, B. C.
10.1101/2024.11.04.621915 — bioinformatics — Posted on 2024-11-08
3524 A Machine Learning Classifier to Identify and Prioritise Genes Associated with Cardiac Development
Kabir, M.; Hartill, V.; Farr, G. H.; Qureshi, W. M. S.; Baross, S. L.; Doig, A. J.; Talavera, D.; Keavney, B. D.; Maves, L.; Johnson, C. A.; Hentges, K. E.
10.1101/2024.11.08.622603 — genomics — Posted on 2024-11-08
3527 Neuropeptides specify and reprogram division of labor in the leafcutter ant Atta cephalotes
Gilbert, M. B.; Glastad, K. M.; Fioriti, M. T.; Sorek, M.; Gannon, T.; Xu, D.; Pino, L. K.; Korotkov, A.; Biashad, A.; Baeza, J.; Lauman, R.; Filippova, A.; Kacsoh, B.; Bonasio, R.; Mathis, M. W.; Garcia, B.; Seluanov, A.; Gorbunova, V.; Berger, S. L.
10.1101/2024.11.07.622473 — molecular biology — Posted on 2024-11-08
3528 A multivalent adaptor mechanism drives the nuclear import of proteasomes
Brunner, H. L.; Kalis, R. L.; Grundmann, L.; Hodakova, Z.; Koskova, Z.; Grishkovskaya, I.; de Almeida, M.; Hinterndorfer, M.; Hoefflin, S.; Andersch, F.; Kotisch, H.; Dickmanns, A.; Cuylen-Haering, S.; Zuber, J.; Haselbach, D.
10.1101/2024.11.08.622636 — molecular biology — Posted on 2024-11-08
3529 Evaluating the Survival and Removal of Escherichia coli from Surfaces Made with Traditional and Sustainable Cement-Based Materials in Field-Relevant Conditions
Anderson, C. E.; Hernandez, J.; Hanif, S.; Owens, L.; Crider, Y.; Billington, S. L.; Lepech, M.; Boehm, A. B.; Benjamin-Chung, J.
10.1101/2024.11.07.622504 — microbiology — Posted on 2024-11-08
3530 Gut Microbial Utilization of the Alternative Sweetener, D-Allulose, via AlsE
Ndjite, G. M.; Jiang, A. K.; Ravel, C. T.; Grant, M. R.; Jiang, X.; Hall, B.
10.1101/2024.11.07.622513 — microbiology — Posted on 2024-11-08
3531 Enhancement and validation of the antibiotic resistance prediction performance of a cloud-based genetics processing platform for Mycobacteria
Westhead, J.; Baker, C. S.; Brouard, M.; Colpus, M.; Constantinides, B.; Hall, A.; Knaggs, J.; Lopes Alves, M.; Spies, R.; Thai, H.; Surrall, S.; Govender, K.; Peto, T. E.; Crook, D. W.; Omar, S. V.; Turner, R.; Fowler, P. W.
10.1101/2024.11.08.622466 — microbiology — Posted on 2024-11-08
3534 Microbial Partner (MiPner) Analysis
Bennetzen, J. L.; Fernandez Canela, J.; Elmgreen, V.; McCann, S. R.; Norris, M. E.; Deng, X.; Brailey-Jones, P.
10.1101/2024.11.08.622289 — microbiology — Posted on 2024-11-08
3536 Complex optogenetic spatial patterning with split recombinase
Kinstlinger, I. S.; Neu, E. M.; Mowry, S. K.; Tous, C.; Kotton, D. N.; Wong, W.
10.1101/2024.11.07.622567 — synthetic biology — Posted on 2024-11-08
3538 Optimizing Lipidomics Analysis Workflows for Biological Fluids and Extracellular Vesicles with Integrated Liquid Chromatography Tandem Mass Spectrometry Approaches
Vilela, A. F. L.; Patricio, M. R.; Defelippo-Felippe, T. V.; Nardini, V.; Pontes, N. N. H.; Carvalho, J. C.; Nobre-Azevedo, P.; Rodrigues, D. L.; Oliveira, B. T. M.; da Silva-Neto, P. V.; Fernandes, A. P. M.; Almeida, F.; Faccioli, L. H.; Sorgi, C. A.
10.1101/2024.11.08.622653 — biochemistry — Posted on 2024-11-08
3539 Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation
Kalaycioglu, M.; Gilkis, M.; Lee, K. M.; Chatterjee, S.; Balu, K.; Ratcliffe, J. E.; Castro, E.; Almahdor, D.; Caglayan, M.
10.1101/2024.11.07.622578 — biochemistry — Posted on 2024-11-08
3540 Exploring Mechanisms of Action in Combinatorial Therapy through Stability/Solubility Alterations: Advancing AML Treatment
Gholizadeh, E.; Zangene, E.; Vadadokhau, U.; Ritz, D.; Soliymani, R.; Miettinen, J. J.; Baumann, M.; Wilhelm, M.; Heckman, C. A.; Saei, A. A.; Jafari, M.
10.1101/2024.11.08.618644 — biochemistry — Posted on 2024-11-08
3541 Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification
Li, M. J.; Meyer, L. C.; Meier, N.; Witte, J.; Maldacker, M.; Seredynska, A.; Schueler, J.; Schilling, O.; Foell, M. C.
10.1101/2024.11.08.622662 — biochemistry — Posted on 2024-11-08
3542 Preliminary report on the molecular epidemiology of mpox, South Africa 2024
Featherston, J.; Grobbelaar, A.; Glass, A.; Goedhals, D.; Hoek, K.; Maritz, J.; Govender, K.; Govender, N.; Ismail, A.; le Roux, C.; Marshall, T.; Morobadi, D.; Moodley, M.; Moolla, N.; Mtshali, S.; Msimang, V.; Vardas, E.; Weyer, J.
10.1101/2024.11.07.622575 — microbiology — Posted on 2024-11-08
3543 SARS-CoV-2 JN.1 reveals attenuated pathogenicity and airborne transmission
Liu, R.; Jin, Q.; Wang, W.; Zhang, C.; Zhang, H.; Li, B.; Yan, F.; Xia, X.; Li, J.; Wang, X.; Gao, Y.
10.1101/2024.11.07.622580 — microbiology — Posted on 2024-11-08
3546 Physiological stress response to sulfide exposure of freshwater anaerobic methanotrophic archaea
Echeveste Medrano, M. J.; Lee, S.; de Graaf, R.; Holohan, B. C.; Sanchez-Andrea, I.; Jetten, M. S. M.; Welte, C.
10.1101/2024.11.08.622618 — microbiology — Posted on 2024-11-08
3549 Effects of Soluble Electron Shuttles on Microbial Iron Reduction and Methanogenesis
Thapa, B. S.; Flynn, T. M.; Jensvold, Z. D.; Kemner, K.; Sladek, M.; O'Loughlin, E. J.; Marshall, C. W.
10.1101/2024.11.07.622564 — microbiology — Posted on 2024-11-08
3550 Lineage-specific neutralising antibodies after SARS-CoV-2 mild disease. Immune boosting effect of vaccination
Davina-Nunez, C.; Perez, S.; Cabrera-Alvargonzalez, J. J.; Gonzalez-Alonso, E.; Silva-Bea, S.; Rodriguez-Perez, M.; Perez-Gonzalez, A.; del Campo, V.; Figueroa-Lamas, M. d. P.; Rojas, A.; Mendoza, J.; Regueiro-Garcia, B. J.
10.1101/2024.11.08.622599 — microbiology — Posted on 2024-11-08
3551 Methanotrophic flexibility of Ca. Methanoperedens and its interactions with sulfate-1 reducing bacteria in the sediment of meromictic Lake Cadagno
Echeveste Medrano, M. J.; Su, G.; Blattner, L. A.; Leao, P.; Sanchez-Andrea, I.; Jetten, M. S. M.; Welte, C. U.; Zopfi, J.
10.1101/2024.11.08.622632 — microbiology — Posted on 2024-11-08
3552 Contrasted viral communities between Aedes albopictus and Culex quinquesfasciatus in La Reunion Island
Francois, S.; Antoine-Lorquin, A.; Mutuel, D.; Makoundou, P.; Perriat-Sanguinet, M.; Unal, S.; Sobry, H.; Gosselin-Grenet, A.-S.; Ogliastro, M.; Sicard, M.; Weill, M.; Atyame, C.; Boëte, C.
10.1101/2024.11.08.622592 — microbiology — Posted on 2024-11-08
3553 Follicular Bcl6 reactivity is associated with a unique immune landscape and spatial transcriptome in COVID-19
Brenna, C.; Mora, B. B.; Ioannidou, K.; Burgermeister, S.; Bodelet, J.; Siebmanns, M.; Georgakis, S.; Orfanakis, M.; Sedille, N.; Feinstein, M.; Lomasney, J. W.; Chen, O. Y.; Pantaleo, G.; Berezowska, S.; De Leval, L.; Gottardo, R.; Petrovas, C.
10.1101/2024.11.07.622471 — immunology — Posted on 2024-11-08
3554 The Tailtag System: Tracking Multiple Mice in a Complex Environment Over a Prolonged Period Using ArUco Markers.
Coulombe, V.; Rivera, A. M.; Monfared, S.; Roussel, D.-A.; Leboulleux, Q.; Peralta, M. R.; Gosselin, B.; Labonte, B.
10.1101/2024.11.07.622536 — animal behavior and cognition — Posted on 2024-11-08
3557 RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing
Wu, T.; Chen, Z.; Zhang, Z.; Zhou, X.; Gu, Y.; Dinenno, F. A.; Chen, J.
10.1101/2024.11.07.622565 — developmental biology — Posted on 2024-11-08
3558 Critical role of Spatio-Temporally Regulated Maternal RNAs in Zebrafish Embryogenesis
Kushawah, G.; Amaral, D. B.; Hassan, H.; Gogol, M. M.; Nowotarski, S. H.; Bazzini, A. A.
10.1101/2024.11.07.622483 — developmental biology — Posted on 2024-11-08
3560 Donor embryonic stem cells impede host epiblast specification in 8-cell stage chimeras by crowding and FGF4 signalling
Strawbridge, S. E.; Schrattel, A. K.; Humphreys, P.; Jones, K. A.; Artus, J.; Hadjantonakis, A.-K.; Fletcher, A. G.; Nichols, J.
10.1101/2024.11.08.622647 — developmental biology — Posted on 2024-11-08
3563 Pathological tau alters head direction signaling and induces spatial disorientation
Jiang, S.; Hijazi, S.; Sarkany, B.; Gautsch, V. G.; Lachance, P. A.; Hasselmo, M. E.; Bannerman, D.; Viney, T. J.
10.1101/2024.11.07.622548 — neuroscience — Posted on 2024-11-08
3566 Axonal spheroids are regulated by Schwann cells after peripheral nerve injury
Hunter-Chang, S.; Kim-Aun, C.; Karim, H.; Jones, M.; Vegiraju, T.; Stepanova, E.; Manke, B.; Kucenas, S.; Deppmann, C. D.
10.1101/2024.11.08.622649 — neuroscience — Posted on 2024-11-08
3567 Cortical contributions to attentional orienting and response cancellation in action stopping
Kemp, S. A.; Salomoni, S.; Bazin, P.-L.; Pash, L.; St George, R. J.; Hinder, M. R.
10.1101/2024.11.08.622650 — neuroscience — Posted on 2024-11-08
3568 Hormonal contraceptive intake during adolescence and cortical brain measures in the ABCD Study
Heller, C.; Dhamala, E.; Bottenhorn, K. L.; Herting, M.; Bosse, B.; De La Rosa, J. S.; Farland, L. V.; Allen, A.; Barth, C.; Petersen, N.
10.1101/2024.11.07.622544 — neuroscience — Posted on 2024-11-08
3569 Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons
Le Bail, R.; Lakaye, B.; Espuny Camacho, I.; Engel, D.; Silva, C.; Nguyen, L.
10.1101/2024.11.08.622673 — neuroscience — Posted on 2024-11-08
3572 BLAKOR inputs to the BNST regulate social stress-escalated alcohol consumption
Maiya, R.; Paliarin, F.; Duplantis, C.; Dore, E.; Basavanhalli, S.; Weiser, E.; Jones, T.; Maiya, R.
10.1101/2024.11.07.622470 — neuroscience — Posted on 2024-11-08
3573 Paired and solitary ionocytes in the zebrafish olfactory epithelium
Peloggia, J.; Cheung, K. Y.; Whitfield, T. T.; Petkova, M.; Schalek, R.; Boulanger-Weill, J.; Wu, Y.; Wang, S.; van Hateren, N. J.; Januszewski, M.; Jain, V.; Lichtman, J. W.; Engert, F.; Piotrowski, T.; Jesuthasan, S.
10.1101/2024.11.08.620918 — neuroscience — Posted on 2024-11-08
3574 Adducins regulate morphology and fate of neural progenitors during neocortical neurogenesis
Ossola, C.; Cokorac, N.; Faletti, S.; Capra, E.; Bertani, I.; Ambrosini, C.; Faga, G.; Kalebic, N.
10.1101/2024.11.08.622634 — neuroscience — Posted on 2024-11-08
3575 Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
Katayama, H.; Dou, R.; Leon-Letelier, R. A.; Irajizad, E.; Sevillano, A.; Park, S.; Hsiao, F. C.; Cai, Y.; Vykoukal, J.; Fahrmann, J. F.; Dennison, J. B.; Barrientos-Toro, E.; Raso, M. G.; Sahin, A.; Hanash, S. M.
10.1101/2024.11.07.622456 — cancer biology — Posted on 2024-11-08
3576 DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides
Ren, Q.; Wang, J.; Idikuda, V.; Zhang, S.; Shin, J.; Ludlam, W. G.; Real Hernandez, L. M.; Levental, I.; Martemyanov, K.; Chanda, B.; Bao, H.
10.1101/2024.11.07.622281 — biophysics — Posted on 2024-11-08
3577 Global kinetic model of lipid-induced alpha-synuclein aggregation and its inhibition by small molecules
Stevenson, A.; Staats, R.; Dear, A. J.; Voderholzer, D.; Guido, R.; Meisl, G.; Galvagnion, C.; Buell, A. K.; Knowles, T. P. J.; Vendruscolo, M.; Michaels, T. C. T.
10.1101/2024.11.07.622437 — biophysics — Posted on 2024-11-08
3578 Better Prior Distribution for Antibody Complementarity-Determining Regions Design
Wu, J.; Kong, X.; Sun, N.; Wei, J.; Shan, S.; Feng, F.; Wu, F.; Peng, J.; Zhang, L.; Liu, Y.; Ma, J.
10.1101/2024.11.07.622422 — bioinformatics — Posted on 2024-11-08
3580 Random subsamples of animal populations can reveal intrinsic differences in sociality with key implications in ecology, conservation and disease transmission
Conteddu, K.; Kaur, P.; Brown, M.; Fennessy, J.; Fennessy, S.; Hart, E.; Amin, B.; David, A.; Griffin, L. L.; Faull, J.; Grignolio, S.; Brivio, F.; Haigh, A.; Kirwan, L.; Salter-Townshend, M.; Ciuti, S.
10.1101/2024.11.07.622426 — ecology — Posted on 2024-11-08
3582 IL-10 Targets IRFs to Suppress IFN and Inflammatory Response Genes by Epigenetic Mechanisms
Mishra, B.; Bachu, M.; Wingert, C.; Yuan, R.; Chaudhary, V.; Braunner, C.; Bell, R.; Ivashkiv, L.
10.1101/2024.11.07.622491 — immunology — Posted on 2024-11-08
3583 Investigating the consequences of the mating system for drug resistance evolution in C. elegans
Trubenova, B.; Hellinga, J.; Krücken, J.; von Samson-Himmelstjerna, G.; Schulenburg, H.; Regoes, R. R.
10.1101/2024.11.07.620884 — evolutionary biology — Posted on 2024-11-08
3586 Strong family- and guild-specific responses of arbuscular mycorrhizal fungi to long-term deficiencies and imbalances of N, P and K
Jenab, K.; Alteio, L.; Guseva, K.; Gorka, S.; Darcy, S.; Fuchslueger, L.; Canarini, A.; Martin, V. S.; Wiesenbauer, J.; Spiegel, F.; Imai, B.; Schmidt, H.; Hage-Ahmed, K.; Poetsch, E.; Richter, A.; Jansa, J.; Kaiser, C.
10.1101/2024.11.06.622229 — ecology — Posted on 2024-11-08
3587 RNA methylation controls stress granule formation and function during erythropoiesis
GUNAGE, R. D.; Lin, S.; Wiley, D.; Choudhuri, A.; Smith, M.; Han, T.; Shah, A.; Coyne, S.; Koczirka, K.; Zhi Ming Chen, K.; Yu, C.; Drake, K.; Yang, X.; Yang, S.; Zhou, Y.; Bauer, D.; Qian, Z.; Calo, E.; Gregory, R.; Zon, L.
10.1101/2024.11.07.622459 — cell biology — Posted on 2024-11-08
3589 TomoScore: A Neural Network Approach for Quality Assessment of Cellular cryo-ET
Tan, X.; Boniuk, E.; Abraham, A.; Zhou, X.; Yu, Z.; Ludtke, S. J.; wang, z.
10.1101/2024.11.06.622356 — biophysics — Posted on 2024-11-08
3593 Benchmarking of T-Cell Receptor - Epitope Predictors with ePytope-TCR
Drost, F.; Chernysheva, A.; Albahah, M.; Kocher, K.; Schober, K.; Schubert, B.
10.1101/2024.11.06.622261 — bioinformatics — Posted on 2024-11-08
3594 Guidance for the design and analysis of cell-type specific epigenetic epidemiology studies.
Walker, E. M.; Dempster, E. L.; Franklin, A.; Klokkaris, A.; Chioza, B.; Davies, J. P.; Blake, G. E.; Burrage, J.; Policicchio, S.; Bamford, R. A.; Schalkwyk, L. C.; Mill, J.; Hannon, E.
10.1101/2024.11.06.621949 — bioinformatics — Posted on 2024-11-08
3600 Winter Survival of Culex pipiens f. pipiens Adults in Central Greece
Ioannou, C.; Beleri, S.; Tserkezou, P.; Michaelakis, A.; Patsoula, E.; Hadjichristodoulou, C.; Papadopoulos, N. T.
10.1101/2024.11.06.622242 — ecology — Posted on 2024-11-08
3602 Exploring Organ-Specific Extracellular Vesicles in Metabolic Improvements Following Bariatric Surgery in Adolescents with Obesity
Kim, A.; Okura, T.; Choi, K.; Gill, R.; Borra, V.; Murakami, K.; Poulos, A.; Zhang, X.; Jenkins, T.; Shah, A.; Helmrath, M.; Nakamura, T.
10.1101/2024.11.07.622509 — cell biology — Posted on 2024-11-08
3604 The biotoxin BMAA promotes mesenchymal transition in neuroblastoma cells
Moore, E.; Renner, A.; Dowden, T.; Messer, D.; Hansen, H.; Mull, M.; Goebel, A.; Mawawa, G.; Burton, B.; Pawlus, M. R.
10.1101/2024.11.07.622435 — molecular biology — Posted on 2024-11-08
3605 An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor
Wang, S.; Woods, E. C.; Jo, J.; Zhu, J.; Hansel-Harris, A.; Holcomb, M.; Pedowitz, N. J.; Upadhyay, T.; Bennett, J. M.; Fellner, M.; Park, K. W.; Zhang, A.; Valdez, T. A.; Forli, S.; Chan, A. I.; Cunningham, C.; Bogyo, M.
10.1101/2024.11.06.622387 — microbiology — Posted on 2024-11-08
3606 Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us?
Sanz-Munoz, I.; Sanchez-Martinez, J.; Rodriguez-Crespo, C.; Concha-Santos, C. S.; Hernandez, M.; Rojo-Rello, S.; Dominguez-Gil, M.; Mostafa, A.; Martinez-Sobrido, L.; Eiros, J. M.; Nogales, A.
10.1101/2024.11.06.622244 — immunology — Posted on 2024-11-08
3607 A type-specific B cell epitope at the apex of Outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi
Vance, D.; Freeman-Gallant, G.; McCarthy, K.; Piazza, C. L.; Chen, Y.; Vorauer, C.; Muriuki, B.; Rudolph, M. J.; Cavacini, L.; Guttman, M.; MANTIS, N. J.
10.1101/2024.11.06.622094 — immunology — Posted on 2024-11-08
3608 A cereblon (CRBN) molecular glue degrader of NIMA-related kinase 7 (NEK7) reveals a context-dependent role in NLRP3 inflammasome activation
Sylvain, A.; Stoehr, N.; Ma, F.; Cernijenko, A.; Schroeder, M.; Khoshouei, M.; Vogelsanger, M.; Schoenboerner, M.; Burke, A.; Pasupuleti, R.; Solomon, J.; Paulk, J.; Xu, L.; Dawson, J.; Begue, D.; Lefeuvre, P.; Ahrne, E.; Hofmann, A.; Dickson, C. J.; Arabin, P.; Zimmerlin, A.; Kiffe, M.; Froehlicher, M.; Boersig, T.; Elhajouji, A.; Brichet, M.; Menon, S.; Liu, S.; Mueller, M.; Wartchow, C.; Lin, J.; Cardona Gloria, Y.; Dickhoefer, S.; Weber, A. N. R.; Welzel, T.; Kuemmerle-Deschner, J.; Farady, C. J.; Pulz, R.; Bornancin, F.; Buckley, D. L.; Bassi, Z. I.
10.1101/2024.11.06.622079 — immunology — Posted on 2024-11-08
3611 Deep Multimodal Representations and Classification of First-Episode Psychosis via Live Face Processing
Singh, R.; Zhang, Y.; Bhaskar, D.; Srihari, V.; Tek, C.; Zhang, X.; Noah, J. A.; Krishnaswamy, S.; Hirsch, J.
10.1101/2024.11.07.622469 — neuroscience — Posted on 2024-11-08
3613 Systematic review and meta-analysis of bulk RNAseq studies in human Alzheimer's disease brain tissue
Heberle, B. A.; Fox, K. L.; Libermann, L. L.; Xavier, S. R. M.; Dallarosa, G. T.; Santos, R. C.; Fardo, D. W.; Viola, T. W.; Ebbert, M. T. W.
10.1101/2024.11.07.622520 — neuroscience — Posted on 2024-11-08
3617 Stalling of the endometrial decidual reaction determines the recurrence risk of miscarriage risk
Muter, J.; Kong, C.-S.; Taus Nebot, M.; Tryfonos, M.; Vrljicak, P.; Brighton, P. J.; Dimakou, D.; Vickers, M.; Yoshihara, H.; Ott, S.; Tan, B.; Bennet, P.; Quenby, S.; Richter, A.; Van de Velde, H.; Lucas, E.; Brosens, J.
10.1101/2024.11.07.622412 — physiology — Posted on 2024-11-08
3619 Pancreatic changes in obese mice supplemented with vitamin D
da Rocha, G.; dos Santos, N. P.; Mendonca, J. C.; Fassis, N. O. B.; Calsa, B.; Milanski, M.; Amaral, M. E.
10.1101/2024.11.07.622429 — physiology — Posted on 2024-11-08
3622 Human adipose-derived mesenchymal stromal cells improved wound healing in enterocutaneous fistulizing disease mouse model
Marsiano, N.; Levi, Y.; Schneider, P.; Schouten, I.; Nisim-Eliraz, E.; Yagel, S.; Kong, K.-F.; Lombardo, E.; Shpigel, N. Y.
10.1101/2024.11.07.622127 — pathology — Posted on 2024-11-08
3623 Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes
Uusküla-Reimand, L.; Lee, C. A.; Oh, R. H.; Klein, Z. P.; Adler, N.; Alvi, S. A.; Langille, E.; Pasini, E.; Cheng, K. C.; Abd-Rabbo, D.; Hou, H.; Tsai, R.; Bhat, M.; Schramek, D.; Wilson, M. D.; Reimand, J.
10.1101/2024.11.06.622320 — cancer biology — Posted on 2024-11-08
3624 Uttroside B, a US-FDA-Designated Orphan Drug Against Hepatocellular Carcinoma (HCC), Impedes Non-alcoholic Steatohepatitis (NASH) and NASH -Induced HCC
Rayginia, T. P.; Keerthana, C. K.; Aiswarya, S. U.; Sadiq, S. C.; S, J.; Varma, S. S.; P, M. J.; Swetha, M.; Retnakumary, A. P.; Nath, L. R.; Kalimuthu, K.; Jaikumar, V. S.; Sundaram, S.; Anto, N. P.; Isakov, N.; Harikumar, K. B.; Lankalapalli, R. S. B.; Anto, R. J.
10.1101/2024.11.06.622394 — cancer biology — Posted on 2024-11-08
3625 YY1 Enhances the Stability of HIF-1α Protein by Interacting with NUSAP1 in Macrophages within the Prostate Cancer Microenvironment
Li, W.; Chen, S.; Lu, J.; Mao, W.; Zheng, S.; Zhang, M.; Wu, T.; Chen, Y.; Lu, K.; Chu, C.; Shu, C.; Hou, Y.; Yang, X.; Shi, N.; Chen, Z.; Zhang, L.; Zhang, L.; Na, R.; Chen, M.; Ju, S.; Zhang, D.; Ma, Y.; Xu, B.
10.1101/2024.11.07.622424 — cancer biology — Posted on 2024-11-08
3626 Copper induces p53 unfolding in cancer cells, resulting in invasion and chemoresistance
Muller, P. A. J.; Bell, S. J.; Richards, H. L.; Massey, E. J.; Newson, Z.; Tarrant, E.; Morrison, M.; Galvin, M.; Simpson, K.; Le Quesne, J.; Aschauer, L.; von Grabowiecki, Y.
10.1101/2024.11.07.622423 — cancer biology — Posted on 2024-11-08
3628 Denoising Reveals Low-Occupancy Populations in Protein Crystals
Fadini, A.; Apostolopoulou, V.; Lane, T. J.; van Thor, J. J.
10.1101/2024.11.06.622276 — biophysics — Posted on 2024-11-08
3632 Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence
Rios, M. S.; Ripoll-Cladellas, A.; Omidi, F.; Ballouz, S.; Alquicira-Hernandez, J.; Oelen, R.; Franke, L.; van der Wijst, M. G. P.; Powell, J. E.; Mele, M.
10.1101/2024.11.06.622096 — bioinformatics — Posted on 2024-11-08
3633 BaNDyT: Bayesian Network modeling of molecular Dynamics Trajectories
Mukhaleva, E.; Manookian, B.; Chen, H.; Ma, N.; Wei, W.; Urbaniak, K.; Gogoshin, G.; Bhattacharya, S.; Vaidehi, N.; RODIN, A. S.; Branciamore, S.
10.1101/2024.11.06.622318 — bioinformatics — Posted on 2024-11-08
3635 Harnessing micrometer-scale tPA beads for high plasmin flux and accelerated fibrinolysis
Osmond, M. J.; Dabertrand, F.; Quillinan, N.; Su, E. J.; Lawrence, D. A.; Marr, D. W. M.; Neeves, K. B.
10.1101/2024.11.06.621942 — bioengineering — Posted on 2024-11-08
3639 Image-based DNA Sequencing Encoding for Detecting Low-Mosaicism Somatic Mobile Element Insertions
Tan, M.; Lin, Z.; Chen, Z.; Park, J.; He, Z.; Zhou, H.; Lee, E. A.; Gao, Z.; Zhu, X.
10.1101/2024.11.07.619809 — genomics — Posted on 2024-11-08
3642 Evolutionarily guided transcription factor design programs novel T cell states
Takacsi-Nagy, O.; Hartman, A.; Chen, A. Y.; Yin, Y.; Reeder, G. C.; Kernick, C.; Lu, J.; McClellan, A. K.; Raposo, C. J.; Theberath, N. E.; Yan, P. K.; Eyquem, J.; Roth, T. L.; Satpathy, A. T.
10.1101/2024.11.06.622344 — genetics — Posted on 2024-11-08
3650 Epigenetic potential and dispersal propensity in a free-living songbird: a spatial and temporal approach
Jimeno, B.; Tangili, M.; Dominguez, J. C.; Canal, D.; Camacho, C.; Potti, J.; Garcia, J. T.; Martinez-Padilla, J.; Ravinet, M.
10.1101/2024.11.07.622405 — ecology — Posted on 2024-11-08
3652 Dystrophin interacts with Msp300 to Regulate Myonuclear Positioning and Microtubule Organization
Padilla, J. R.; Qiu, Y.; Aleck, G.; Ferreria, L.; Wu, S.; Gibbons, W.; Mandigo, T. R.; Folker, E. S.
10.1101/2024.11.07.622444 — cell biology — Posted on 2024-11-08
3653 LUMIC: Latent diffUsion for Multiplexed Images of Cells
Hung, A. Z.; Zhang, C. J.; Sexton, J. Z.; O'Meara, M. J.; Welch, J. D.
10.1101/2024.11.06.622339 — molecular biology — Posted on 2024-11-08
3654 Amyloid signaling in antiphage defense
Ibarlosa, L.; Dheur, S.; Sanchez, C.; Deb, S.; Granger-Farbos, A.; Linares, V. C.; Berbon, M.; Massoni-Laporte, A.; Salin, B.; Blancard, C.; Saragaglia, C.; Tene, X. M.; Dufour, N.; Rossier, O.; Habenstein, B.; Debarbieux, L.; Kauffmann, B.; Loquet, A.; Saupe, S. J.
10.1101/2024.11.07.622273 — microbiology — Posted on 2024-11-08
3655 Late killing of Plasmodium berghei in the liver by an anti-circumsporozoite protein monoclonal antibody
Aguirre-Botero, M. C.; Pacios, O.; Celli, S.; Aliprandini, E.; Gladston, A.; Thiberge, J.-M.; Formaglio, P.; Amino, R.
10.1101/2024.04.30.591864 — microbiology — Posted on 2024-11-08
3657 ENaC contributes to macrophage dysfunction in cystic fibrosis
Moran, J.; Pugh, C.; Brown, N.; Thomas, A.; Zhang, S.; McCauley, E.; Cephas, A.; Shrestha, C.; Partida-Sanchez, S.; Bai, S.; Bruscia, E. M.; Kopp, B.
10.1101/2024.11.06.622340 — immunology — Posted on 2024-11-08
3658 Sex-specific attenuation of photoreceptor degeneration by reserpine in a rhodopsin P23H rat model of autosomal dominant retinitis pigmentosa
Song, H. B.; Campello, L.; Mondal, A.; Chen, H. Y.; English, M. A.; Glen, M.; Vanlandingham, P.; Farjo, R.; Swaroop, A.
10.1101/2024.11.06.622146 — neuroscience — Posted on 2024-11-08
3662 Metaproteomic profiling of the secretome of a granule-forming Ca. Accumulibacter enrichment
van Olst, B.; Eerden, S. A.; Estok, N. A.; Roy, S.; Abbas, B.; Lin, Y.; van Loosdrecht, M.; Pabst, M.
10.1101/2024.11.06.622250 — systems biology — Posted on 2024-11-08
3665 Phytoassisted synthesis of biogenic silver nanoparticles using Vernonia amygdalina leaf extract: characterization, antibacterial, anti-inflammatory, and acute toxicity profile
Nyuyfoni, G. F.; Nkana, B. P.; Deli, V.; Kedi, P. B. E.; Ntoumba, A. A.; Nanga, C. C.; Tchatchouang, G. C.; Djuidje, A. G.; Djimefo, T. A. K.; Evouna, M. I. D.; Malolo, E. F.-A.; Eha-Kang, C.; Kwati, L.; Ndzeidze, G. N.; Gbambie, A. P.; Francois, E. M.
10.1101/2024.10.31.621348 — pharmacology and toxicology — Posted on 2024-11-08
3670 Whole-genome sequencing across space and time reveals impact of population decline and reduced gene flow in Florida Scrub-Jays
Nguyen, T. N.; Cosgrove, E. J.; Chen, N.; Lehr, N.; Lokey, M.; Beaudry, F. E. G.; Fitzpatrick, S. W.; Miller, K. E.; Fitzpatrick, J. W.; Clark, A. G.
10.1101/2024.11.05.622154 — genomics — Posted on 2024-11-08
3672 Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe
Dagostin, F.; Erazo Quintero, D.; Marini, G.; Da Re, D.; Tagliapietra, V.; Avdicova, M.; Avsic-Zupanc, T.; Dub, T.; Fiorito, N.; Knap, N.; Gossner, C. M.; Kerlik, J.; Makela, H.; Markowicz, M.; Olyazadeh, R.; Richter, L.; Wint, W.; Zuccali, M. G.; Zygutiene, M.; Dellicour, S.; Rizzoli, A.
10.1101/2024.10.18.619031 — ecology — Posted on 2024-11-08
3674 Phlorotannin rich Ascophyllum nodosum seaweed extract inhibits influenza infection
Mega, D. F.; Sharma, P.; Kipar, A.; Hetzel, U.; Bramwell, C.; Meritt, A.; Wright, S.; Plummer, C.; Urbanowicz, R. A.; Stewart, J. P.
10.1101/2024.08.08.606782 — microbiology — Posted on 2024-11-08
3676 Prior expectations about own abilities bias self-belief formation and hinder subsequent revision
Schröder, A.; Czekalla, N.; Mayer, A. V.; Zhang, L.; Stolz, D. S.; Korn, C. W.; Diekelmann, S.; Luebber, F.; Paulus, F. M.; Müller-Pinzler, L.; Krach, S.
10.1101/2024.08.30.610443 — neuroscience — Posted on 2024-11-08
3677 Endurance Exercise Elevates Plasma Mature Brain-Derived Neurotrophic Factor through Child- and Adulthood, with Amplified Effects in Adults
Edman, S.; Starck, J.; Corell, L.; Hangasjarvi, W.; von Finckenstein, A.; Reimeringer, M.; Reitzner, S. M.; Norrbom, J.; Moberg, M.; von Walden, F.
10.1101/2024.11.06.622216 — physiology — Posted on 2024-11-08
3679 Spatial multi-omics defines a shared infiltrative signature in glioblastoma at the resection margin
Pai, B.; Ramos, S. I.; Cheng, W. S.; Joshi, T.; Price, G.; Tome-Garcia, J.; Nudelman, G.; Shroff, S.; Beaumont, K.; Raymund, Y.; Sebra, R.; Zaslavsky, E.; Tsankova, N. M.
10.1101/2024.11.05.621879 — cancer biology — Posted on 2024-11-08
3680 Stick of Sticks: Structural Features of the Amyloidogenic Peptide-DNA Complex
Arzamastsev, G.; Zabrodskaya, Y.; Garmay, Y.; Vinogradova, D.; Ivanova, N.; Arutyunyan, A.; Verlov, N.; Burdakov, V.; Baymukhametov, T.; Konevega, A. L.; Ivankov, O.; Gorshkova, Y.; Egorov, V. V.
10.1101/2024.11.05.622117 — biophysics — Posted on 2024-11-08
3681 Fractional Calculus in Epigenetics
Nasrolahpour, H.; Pellegrini, M.; Skovranek, T.
10.1101/2024.11.06.622206 — biophysics — Posted on 2024-11-08
3684 Engineered acetylation patterns drive large-scale chromatin organization in vitro
Fukai, Y.; Kujirai, T.; Wakamori, M.; Kanamura, S.; Yamauchi, L.; Zeraati, S.; Tanegashima, C.; Kadota, M.; Kurumizaka, H.; Umehara, T.; Kawaguchi, K.
10.1101/2024.11.08.622658 — biophysics — Posted on 2024-11-08
3687 Interpretable PROTAC degradation prediction with structure-informed deep ternary attention framework
Chen, Z.; Gu, C.; Tan, S.; Wang, X.; Li, Y.; He, M.; Lu, R.; Sun, S.; Hsieh, C.-Y.; Yao, X.; Liu, H.; Heng, P.-A.
10.1101/2024.11.05.622005 — bioinformatics — Posted on 2024-11-08
3689 Prediction of context-specific regulatory programs and pathways using interpretable deep learning
Doncevic, D.; Ramirez Alvarez, C.; Li, A.; Zhang, Y.; von Bachmann, A.; Noack, K.; Herrmann, C.
10.1101/2024.11.06.622202 — bioinformatics — Posted on 2024-11-08
3690 An extended and improved CCFv3 annotation and Nissl atlas of the entire mouse brain
Piluso, S.; Veraszto, C.; Carey, H.; Delattre, E.; L'Yvonnet, T.; Colnot, E.; Romani, A.; Bjaalie, J. G.; Markram, H.; Keller, D.
10.1101/2024.11.06.622212 — bioinformatics — Posted on 2024-11-08
3694 Characterizing gene expression profiles of various tissue states in stony coral tissue loss disease using a feature selection algorithm
Beavers, K. M.; Gutierrez-Andrade, D.; Van Buren, E. W.; Emery, M. A.; Brandt, M. E.; Apprill, A.; Mydlarz, L. D.
10.1101/2024.11.05.622084 — genomics — Posted on 2024-11-08
3695 Parallel in-depth analysis of repeat expansions: an updated Clin-CATS workflow for nanopore R10 flow cells
Scholz, V.; Schoenrock, V.; Erdmann, H.; Prokosch, V.; Schoedel, M.; Almus, M.; Sauer, M.; Mayer, V.; Breithausen, E.; van Buren, I.; Dineiger, C.; Heintz, C.; Hallermayr, A.; Neuhann, T.; Holinski-Feder, E.; Abicht, A.; Benet-Pages, A.; Lucas, M. C.
10.1101/2024.11.05.622099 — genetics — Posted on 2024-11-08
3698 Too hot for the weeds? Exploring the impact of climate change in herbaceous Convolvulaceae in Cerrado and Mata Atlantica biomes (SE Brazil)
Barbosa, J. C. J.; Alves, F. V. S.; Moreira, A. L. C.; Loeuille, B.; Chatrou, L. W.; Simao-Bianchini, R.; Simoes, A. R. G.
10.1101/2024.11.06.621913 — ecology — Posted on 2024-11-08
3701 Polyhydroxybutyrate production in freshwater SAR11 (LD12)
Bennett, B. D.; Meier, D. A.; Lanclos, V. C.; Asrari, H.; Coates, J. D.; Thrash, J. C.
10.1101/2024.11.08.622676 — microbiology — Posted on 2024-11-08
3702 Integrated, high-dimensional analysis of CD4 T cell epitope specificities and phenotypes reveals unexpected diversity in the response to Mycobacterium tuberculosis
Mead, H. L.; Kirschman, J. H.; Harms, C. E.; Kelley, E. J.; Soria-Bustos, J.; Nelson, G. A.; Ogongo, P.; Ouma, G.; Ouma, S. G.; Ernst, J. D.; Altin, J. A.
10.1101/2024.11.05.622086 — immunology — Posted on 2024-11-08
3705 SysQuan: repurposing SILAC mice for the affordable absolute quantitation of the human proteome
Mohammed, Y.; Richard, V. R.; Madlangsakay, I. R.; Lao, Y.; Spicer, V.; Popp, R.; Gaither, C.; Hennecken, L.; Kleinekofort, W.; Zahedi, R. P.; Borchers, C. H.
10.1101/2024.11.05.622109 — systems biology — Posted on 2024-11-08
3707 An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck
Selzer, A. M.; Gerlach, G.; Gonzalez-Areizaga, G.; Wales, T. E.; Cui, S. Y.; Iyer, P.; Engen, J. R.; Camacho, C.; Ishima, R.; Smithgall, T. E.
10.1101/2024.11.05.622136 — pharmacology and toxicology — Posted on 2024-11-08
3710 PDBe tools for an in-depth analysis of small molecules in the Protein Data Bank
Choudhary, P.; Kunnakkattu, I. R.; Nair, S.; Lawal, D. K.; Pidruchna, I.; Afonso, M. Q. L.; Fleming, J. R.; Velankar, S.
10.1101/2024.11.05.622044 — bioinformatics — Posted on 2024-11-08
3711 NovumRNA: accurate prediction of non-canonical tumor antigens from RNA sequencing data
Ausserhofer, M.; Rieder, D.; Facciolla, M.; Lamberti, G.; Lisandrelli, R.; Pellegatta, S.; Trajanoski, Z.; Finotello, F.
10.1101/2024.11.05.622043 — bioinformatics — Posted on 2024-11-08
3719 CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity
Pun, N.; Cytlak, U. M.; Lee, D.; Domingues, R. G.; Cheadle, E. J.; Forster, D.; Williams, K. J.; Graham, G.; Hepworth, M. R.; Travis, M. A.; Illidge, T. M.; Dyer, D. P.
10.1101/2024.11.05.622080 — immunology — Posted on 2024-11-08
3720 Time and temperature-resolved transcriptomic analysis of Arabidopsis splicing-related mutants
Nardeli, S. M.; El Arbi, N.; Dikaya, V.; Rojas-Murcia, N.; Goretti, D.; Schmid, M.
10.1101/2024.11.08.622454 — plant biology — Posted on 2024-11-08
3721 An algal nutrient-replete, optimized medium for fast growth and high triacylglycerol accumulation
Jeffers, T. L.; McCombs, R.; Schmollinger, S.; Merchant, S. S.; Niyogi, K. K.; Roth, M. S.
10.1101/2024.11.07.622501 — plant biology — Posted on 2024-11-08
3728 From aerial drone to QTL: Leveraging next-generation phenotyping to reveal the genetics of color and height in field-grown Lactuca sativa
Dijkhuizen, R. F.; van Eijnatten, A. L.; Mehrem, S. L.; van den Bergh, E. S.; van Lieshout, J.; Spaninks, K.; Kaandorp, S.; Offringa, R.; Proveniers, M.; Van den Ackerveken, G.; Snoek, B. L.
10.1101/2024.11.07.622452 — plant biology — Posted on 2024-11-08
3734 Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum
Lannan, J.; Floyd, C.; Xu, L. X.; Yan, C.; Marshall, W. F.; Vaikuntanathan, S.; Dinner, A. R.; Honts, J. E.; Bhamla, S.; Elting, M. W.
10.1101/2024.11.07.622534 — cell biology — Posted on 2024-11-08
3738 Identification and Characterization of Archaeal Pseudomurein Biosynthesis Genes through Pangenomics
Lupo, V.; Roomans, C.; Royen, E.; Ongena, L.; Jacquemin, O.; Mullender, C.; Kerff, F.; Baurain, D.
10.1101/2024.11.07.622503 — microbiology — Posted on 2024-11-08
3740 A unified central thalamus mechanism underlying diverse recoveries in disorders of consciousness
Zhang, H.; Ge, Q.; Liu, X.; Dang, Y.; Xu, L.; Zhuang, Y.; Wu, S.; Laureys, S.; He, J.; Yu, S.
10.1101/2024.11.04.621844 — neuroscience — Posted on 2024-11-08
3741 Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders
Jamieson, A. J.; Steward, T.; Davey, C. G.; Ince, S.; Agathos, J. A.; Moffat, B. A.; Glarin, R. K.; Felmingham, K. L.; Harrison, B. J.
10.1101/2024.11.06.622349 — neuroscience — Posted on 2024-11-08
3743 TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes
Rudzitis, C. N.; Lakk, M.; Singh, A.; Redmon, S. N.; Kirdajova, D.; Tseng, Y.-T.; deIeso, M. L.; Stamer, D.; Herberg, S.; Krizaj, D.
10.1101/2024.11.05.622187 — physiology — Posted on 2024-11-08
3744 Hope for Others: Research Results from the University of Pittsburgh Rapid Autopsy Program for Breast Cancer
Chang, A. C.; Balic, M.; Bartholow, T.; Bhargava, R.; Brown, D. D.; Brown, L.; Brufsky, A.; Cao, Y.; Carleton, N.; Clark, A. M.; Cody, M.; Ding, K.; Deible, C.; Elangovan, A.; Foldi, J.; Geisler, D.; Hodgdon, C.; Howard, N.; Li, Z.; Liu, J. B.; Lopez-Nunez, O.; Mary, S. J.; McGinn, O.; Miller, L.; Mori, K.; Pecar, G.; Priedigkeit, N.; Puhalla, S.; Rosenzweig, M. Q.; Roy, P.; Savariau, L.; Walker, S.; Waltermire, H.; Wedn, A. M.; Wells, A.; Yates, M. E.; Xavier, J.; Lee, A. V.; Oesterreich, S.
10.1101/2024.11.06.621982 — cancer biology — Posted on 2024-11-08
3746 Protein-RNA condensation kinetics via filamentous nanoclusters
Peralta Martinez, R.; Visentin, A.; Salgueiro, M.; Borkosky, S. S.; Araujo Ajalla Aleixo, M.; Villares Portugal, R.; Sanchez, I. E.; de Prat Gay, G.
10.1101/2024.11.05.622047 — biophysics — Posted on 2024-11-08
3751 A CONTRIBUTION TO THE ANATOMY OF TWO RARE CETACEAN SPECIES: THE HOURGLASS DOLPHIN (Lagenorhynchus cruciger) AND THE SPECTACLED PORPOISE (Phocoena dioptrica)
Graic, J.-M.; Gerussi, T.; Cozzi, B.; Kot, B. C. W.; Boys, R. M.; Perrott, M.; Fleury, K.; Burns, E.; Webster, T.; Betty, E.; Howarth, O.; Loch, C.; White, S.; Dawson, S.; Rayment, W.; Hunter, S.; Cole, R.; Cox, D.; Young, M.; Roberts, J.; Waterhouse, T.; Smith, R.; Ogle, M.; Fyfe, J.; Hendriks, H.; van Helden, A.; Johnstone, M.; Stewart, R. O.; Fordyce, R. E.; Stockin, K. A.
10.1101/2024.11.06.622215 — evolutionary biology — Posted on 2024-11-08
3754 Endothelial calcium firing mediates extravasation of metastatic tumor cells.
Peralta, M.; Dupas, A.; Larnicol, A.; Lefebvre, O.; Goswami, R.; Stemmelen, T.; Molitor, A.; Carapito, R.; Girardo, S.; Osmani, N.; Goetz, J. G.
10.1101/2024.03.28.587188 — cell biology — Posted on 2024-11-08
3757 The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas
Laurenge, A.; Pugliese, P.; Richard, Q.; Mathon, B.; Jouannet, S.; Hayat, Y.; Scuderi, S.; Marijon, P.; Labreche, K.; Alentorn, A.; Verreault, M.; Idbaih, A.; Birzu, C.; Huillard, E.; Pottier, N.; Desmons, A.; Fayache, I.; Kaas, G. A.; Kingsley, P. J.; Marnett, L. J.; Duplus, E.; El-Habr, E.; Salas, L. A.; Mokhtari, K.; Tran, S.; Touat, M.; Bielle, F.; Suva, M. L.; Iavarone, A.; Ceccarelli, M.; Mallat, M.; Sanson, M.; Castro-Vega, L. J.
10.1101/2024.08.23.608811 — cancer biology — Posted on 2024-11-08
3758 Solu - a Cloud Platform for Real-Time Genomic Pathogen Surveillance
Moilanen, T. J.; Visuri, K.; Lehtinen, J.; Ortega Sanz, I.; Steenwyk, J. L.; Sihvonen, S.
10.1101/2024.05.30.596434 — bioinformatics — Posted on 2024-11-08
3759 Generation of cultured beef from bovine embryonic stem cells
Rui, X.; Li, Z.; Xu, J.; Dai, J.; Zhang, X.; Jin, X.; Liu, Y.
10.1101/2024.10.15.618593 — bioengineering — Posted on 2024-11-08
3760 Detailed in vivo characterization of the players and impact of individual loop extrusion trajectories
Han, R.; Huang, Y.; Robers, M.; Magnitov, M.; Vaandrager, I.; Allahyar, A.; Verstegen, M. J. A. M.; Zhang, K.; de Wit, E.; de Laat, W.; Krijger, P. H. L.
10.1101/2023.01.04.522689 — genomics — Posted on 2024-11-08
3761 Reductive dehalogenation by diverse microbes is central to biogeochemical cycles in deep-sea cold seeps
Han, Y.; Deng, Z.; Peng, Y.; Peng, J.; Cao, L.; Xu, Y.; Yang, Y.; Wu, M.; Zhou, H.; Zhang, C.; Zhang, D.; Wang, M.; Zhang, C.; Greening, C.; Dong, X.
10.1101/2024.01.23.576788 — microbiology — Posted on 2024-11-08
3762 Axenisation of oleaginous microalgal cultures via anoxic photosensitisation.
Iyer, A.; Monissen, M.; Ma, Q.; Osborne, M.; Schaedig, E.; Modin, O.; Halim, R.
10.1101/2024.11.07.622432 — microbiology — Posted on 2024-11-08
3763 Force monitoring reveals single trial dynamics of motor control in a stop signal task
Ramawat, S.; Marc, I. B.; Di Bello, F.; Bardella, G.; Ferraina, S.; Pani, P.; Brunamonti, E.
10.1101/2024.07.05.602195 — neuroscience — Posted on 2024-11-08
3765 Unraveling the impact of host genetics and factors on the urinary microbiome in a young population
Zou, L.; Zhang, Z.; Chen, J.; Guo, R.; Tong, X.; Ju, Y.; Lu, H.; Yang, H.; Wang, J.; Zong, Y.; Xu, X.; Jin, X.; Xiao, L.; Jia, H.; Zhang, T.; Liu, X.
10.1101/2024.05.17.594782 — microbiology — Posted on 2024-11-08
3766 Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
Huang, Y.; Fan, Y.; Liu, Y.; Liu, X.; Li, W.; Yang, Y.; Zhang, Z.; Ma, S.; shuhui, j.; Chen, S.; Shu, H.; Feng, W.; Wang, K.; He, Q.; Qi, W.; Fan, Y.; Li, X.; Liu, M.
10.1101/2024.09.17.613598 — physiology — Posted on 2024-11-08
3768 Evolution of vocal production learning in parrots
Krasheninnikova, A.; Smeele, S. Q.; Snijders, M.; Haldar, E.; Carpenter, J.; Zamora, R.; Naguib, M.; Wolf, J. B. W.; Gahr, M.; von Bayern, A. M.
10.1101/2024.11.05.622162 — evolutionary biology — Posted on 2024-11-08
3770 Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Toward a national plant health risk analysis for Cameroon and Ethiopia
Mouafo-Tchinda, R.; Etherton, B.; Plex Sula, A.; Andrade-Piedra, J.; Ogero, K.; Omondi, B. A.; McEwan, M.; Tene Tayo, P.; Harahagazwe, D.; Cherinet, M.; Gebeyehu, S.; Sperling, L.; Garrett, K. A.
10.1101/2024.02.12.580019 — ecology — Posted on 2024-11-08
3775 TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites
Murphy, R. D.; Troublefield, C. A.; Miracle, J. S.; Young, L. E. A.; Tripathi, A.; Brizzee, C. O.; Dhara, A.; Patwardhan, A.; Sun, R. C.; Vander Kooi, C. W.; Gentry, M. S.; Sinai, A. P.
10.1101/2023.09.29.560185 — microbiology — Posted on 2024-11-08
3777 The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria
Schubert, K.; Braly, M.; Zhang, J.; Muscolo, M. E.; Lam, H. N.; Hug, K.; Moore, H.; McCausland, J. W.; Terciano, D.; Lowe, T.; Lesser, C. F.; Jacobs-Wagner, C.; Wang, H.; Auerbuch, V.
10.1101/2024.10.11.617751 — microbiology — Posted on 2024-11-08
3779 Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI
Autio, J. A.; Uematsu, A.; Ikeda, T.; Ose, T.; Hou, Y.; Magrou, L.; Kimura, I.; Ohno, M.; Murata, K.; Coalson, T.; Kennedy, H.; Glasser, M. F.; Van Essen, D. C.; Hayashi, T.
10.1101/2024.09.27.615294 — neuroscience — Posted on 2024-11-08
3780 A Prefrontal Cortex Map based on Single Neuron Activity
Le Merre, P.; Heining, K.; Slashcheva, M.; Jung, F.; Moysiadou, E.; Guyon, N.; Yahya, R.; Park, H.; Wernstal, F.; Carlen, M.
10.1101/2024.11.06.622308 — neuroscience — Posted on 2024-11-08
3781 Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells
Chen, Y.; Lee, J. H. H.; Li, J.; Park, S.; Perez-Flores, M. C.; Peguero, B.; Kersigo, J.; Kang, M.; Choi, J.; Levine, L.; Gratton, M. A.; Friztsch, B.; Yamoah, E. N.
10.1101/2023.10.08.561387 — neuroscience — Posted on 2024-11-08
3782 Comparative lifespan and healthspan of nonhuman primate species common to biomedical research
Huber, H. F.; Ainsworth, H. C.; Quillen, E. E.; Salmon, A.; Ross, C.; Azhar, A. D.; Bales, K.; Basso, M. A.; Coleman, K.; Colman, R.; Darusman, H. S.; Hopkins, B.; Hotchkiss, C. E.; Jorgensen, M. J.; Kavanagh, K.; Li, C.; Mattison, J. A.; Nathanielsz, P. W.; Saputro, S.; Scorpio, D. G.; Sosa, P.-M.; Vallender, E. J.; Wang, Y.; Zeiss, C. J.; Shively, C. A.; Cox, L. A.
10.1101/2024.07.31.606010 — physiology — Posted on 2024-11-08
3783 Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography
Hollingworth, D.; Herold, K. F.; Kelly, G.; Mykhaylyk, V. B.; Xiang, J.; Zhang, D.; Wallace, B. A.; Hemmings, H. C.
10.1101/2024.11.04.621342 — biophysics — Posted on 2024-11-08
3786 MAVISp: A Modular Structure-Based Framework for Protein Variant Effects
Arnaudi, M.; Beltrame, L.; Degn, K.; Utichi, M.; Scrima, S.; Sanchez-Izquierdo Besora, P.; Krzesinska, K.; Maselli, F.; Dorcakova, T.; Safer, J.; Estad, A. H.; Meldgard, K.; Becker, P.; Sora, V.; Pettenella, A.; Vinhas, J.; Bauer, L.; Saridaki, P.; Melidi, A.; Favaro, L.; Kiachaki, E.; Oswal, A.; Breitenstein, J.; Fas, B. A.; Tedeschi, G.; Sackett, P. W.; Cava, C.; Rohlin, A.; Nilbert, M.; Iqbal, S.; Lambrughi, M.; Tiberti, M.; Papaleo, E.
10.1101/2022.10.22.513328 — bioinformatics — Posted on 2024-11-08
3787 Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities
Lane, L. E.; Doerfler, A. N.; LArgent, L. A.; Touchette, E.; Mills, B.; Bryant, J.; Roller, S. N.; Forsythe, E. S. S.
10.1101/2024.11.01.621607 — bioinformatics — Posted on 2024-11-08
3788 Structure of Trypanosoma peroxisomal import complex unveils conformational dynamics
Sonani, R. R.; Blat, A.; Jemiola-Rzeminska, M. R.; Lipinski, O.; Patel, S. N.; Sood, T.; Dubin, G.
10.1101/2023.04.03.535445 — biochemistry — Posted on 2024-11-08
3792 An ocean of opsins
De Vivo, G.; Pelletier, E.; Feuda, R.; D'Aniello, S.
10.1101/2024.11.07.622103 — evolutionary biology — Posted on 2024-11-08
3796 A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria Framework
Quah, S. K. L.; Jo, B.; Geniesse, C.; Uddin, L. Q.; Mumford, J. A.; Barch, D. M.; Fair, D. A.; Gotlib, I. H.; Poldrack, R. A.; Saggar, M.
10.1101/2024.01.31.577486 — neuroscience — Posted on 2024-11-08
3797 dArc1 controls sugar reward valuation in Drosophila melanogaster
Bervoets, S.; Jacob, M. S.; Devineni, A.; Mahoney, B. D.; Sullivan, K. R.; Butts, A. R.; Sung, H.; Einstein, J.; Metzstein, M. M.; Dus, M.; Shepherd, J. D.; Caron, S. J. C.
10.1101/2024.11.04.621761 — neuroscience — Posted on 2024-11-08
3800 A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat
Cornwell, B. R.; Didier, P. R.; Grogans, S. E.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Hur, J.; Scott, Z. S.; Fox, A. S.; DeYoung, K. A.; Smith, J. F.; Shackman, A. J.
10.1101/2024.07.10.602972 — neuroscience — Posted on 2024-11-08
3804 Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells
Maltsev, A. V.; Subirachs, V. V.; Monfredi, O.; Juhaszova, M.; Warrier, P. A.; Rakshit, S.; Tagirova, S.; Maltsev, A. V.; Stern, M. D.; Lakatta, E. G.; Maltsev, V. A.
10.1101/2024.10.09.617454 — biophysics — Posted on 2024-11-08
3809 Amyloid signaling in antiphage defense
Saupe, S. J.; Ibarlosa, L.; Dheur, S.; Deb, S.; Granger-Farbos, A.; linares, v. c.; Berbon, M.; Massoni-Laporte, A.; Salin, B.; Blancard, C.; Saragaglia, C.; Tene, X. M.; Dufour, N.; Rossier, O.; Habestein, B.; Debarbieux, L.; Kauffmann, B.; Loquet, A.
10.1101/2024.11.07.622273 — microbiology — Posted on 2024-11-07
3811 Development of the Left Arcuate Fasciculus is Linked to Learning Gains in Reading, but not Math
Roy, E.; Harriott, E. M.; Nguyen, T. Q.; Richie-Halford, A.; Rokem, A.; Cutting, L. E.; Yeatman, J. D.
10.1101/2024.11.07.622498 — neuroscience — Posted on 2024-11-07
3817 Jade1 and the HBO1 complex are spatial-selective cofactors of Oct4
Wu, Y.; Manna, A. K.; Li, L.; Handa, H.; Chandrasekharan, M. B.; Tantin, D.
10.1101/2024.11.07.622531 — molecular biology — Posted on 2024-11-07
3819 Upscaling production of immunogenic poliovirus virus-like particles in Pichia Pastoris by controlled fermentation
Sherry, L.; Grehan, K.; Bahar, M. W.; Swanson, J. J.; Fox, H.; Matthews, S. V.; Carlyle, S.; Qin, L.; Porta, C.; Wilkinson, S.; Robb, S.; Clark, N.; Liddell, J.; Fry, E. E.; Stuart, D. I.; Macadam, A.; Rowlands, D. J.; Stonehouse, N. J.
10.1101/2024.11.07.622482 — microbiology — Posted on 2024-11-07
3825 Creating overlapping genes by alternate-frame insertion
Leonard, S. P.; Halvorsen, T. M.; Lim, B.; Park, D.; Jiao, Y.; Yung, M. C.; Ricci, D.
10.1101/2024.11.07.622342 — synthetic biology — Posted on 2024-11-07
3826 A Genetic Toggle Switch in Plants
Kassaw, T. K.; Xu, W.; Zalewski, C. S.; Kiwimagi, K.; Weiss, R.; Antunes, M. S.; Prasad, A.; Medford, J. I.
10.1101/2024.11.07.622546 — synthetic biology — Posted on 2024-11-07
3827 Comprehensive protease specificity profiling
Zhu, B.; Lane, M. D.; Baller, J. A.; Jagtap, P. D.; Griffin, T. J.; Seelig, B.
10.1101/2024.11.06.622033 — biochemistry — Posted on 2024-11-07
3828 Engineered HMGB1 Construct with Tandem HMG B Domains that Promotes Tissue Regeneration without Potential for Deleterious Inflammation or Thrombosis
Vinals Guitart, A.; Lee, C.; Espirito Santo, A.; Ruan, J.-L.; Redfield, C.; Yue, W.; Burgess-Brown, N.; Fedorov, O.; Nanchahal, J.
10.1101/2024.11.06.622383 — biochemistry — Posted on 2024-11-07
3829 Rad52 sorts and stacks Rad51 at the DNA junction to promote homologous recombination
Deveryshetty, J.; Mistry, A.; Pangeni, S.; Ghoneim, M.; Tokmina, M.; Kaushik, V.; Taddei, A.; Ha, T.; Bothner, B.; Antony, E.
10.1101/2024.11.07.622519 — biochemistry — Posted on 2024-11-07
3832 Rab40 GTPases regulate AMBRA1-mediated transcription and cell migration
Sampath, R.; Vaeth, K.; Mikalayeva, V.; Skeberdis, V. A.; Prekeris, R.; Han, K.-j.
10.1101/2024.11.07.622540 — molecular biology — Posted on 2024-11-07
3834 SARS-CoV-2 infection enhancement by Amphotericin B: Implications for disease management
Nguyen, D.; Laidlaw, S. M.; Dong, X.; Wand, M. E.; Horton, A.; Sutton, M.; Tree, J.; Milligan, R.; Erdmann, M.; Matthews, D. A.; Davidson, A. D.; Rahman, K. M.; Hiscox, J. A.; Carroll, M. W.
10.1101/2024.11.07.622419 — microbiology — Posted on 2024-11-07
3837 Phenotypic plasticity in bacterial elongation among closely related species
Delaby, M.; Yang, L.; Jacq, M.; Gallagher, K. A.; Kysela, D. T.; Hughes, V.; Pulido, F.; Veyrier, F. J.; VanNieuwenhze, M. S.; Brun, Y. V.
10.1101/2024.11.07.622495 — microbiology — Posted on 2024-11-07
3838 Competition strategies driving resource partitioning in chitin degrading communities
Pontrelli, S.; Guessous, G.; Trouillon, J.; Krishna, A.; Hwa, T.; Sauer, U.
10.1101/2024.11.07.622309 — microbiology — Posted on 2024-11-07
3839 The Mla pathway promotes Vibrio cholerae re-expansion from stationary phase
Leitner, D. R.; Zingl, F. G.; Morano, A. A.; Zhang, H.; Waldor, M. K.
10.1101/2024.11.07.622497 — microbiology — Posted on 2024-11-07
3841 Comparative Aerosol Persistence of Hypermucoid Klebsiella pneumoniae
Chirichella, N.; Beddingfield, B. J.; Redmann, R.; Norton, E. B.; Kolls, J. K.; ROY, C. J.
10.1101/2024.11.07.622510 — microbiology — Posted on 2024-11-07
3842 Evidence for a role of extraintestinal pathogenic Escherichia coli, Enterococcus faecalis and Streptococcus gallolyticus in the aetiology of exudative cloacitis in the critically endangered kakapo (Strigops habroptilus)
French, R. K.; Waller, S. J.; Wierenga, J. R.; Grimwood, R. M.; Hodgkinson-Bean, J.; Digby, A.; Uddstrom, L.; Eason, D.; Kakapo Recovery Team, ; Argilla, L.; Biggs, P. J.; Cookson, A.; French, N.; Geoghegan, J. L.
10.1101/2024.11.07.622535 — microbiology — Posted on 2024-11-07
3843 Axenisation of oleaginous microalgal cultures via anoxic photosensitisation.
Iyer, A.; Monissen, M.; Ma, Q.; Osborne, M.; Schaedig, E.; Modin, O.; Halim, R.
10.1101/2024.11.07.622432 — microbiology — Posted on 2024-11-07
3845 A Single Chimeric Spike Antigen Induces Pan-Sarbecovirus Immunity
Counoupas, C.; Pino, P.; Armitano, J.; Johansen, M.; Smith, L.; Chan, E.; Ashley, C.; Estape, E.; Troyon, J.; Alca, S.; Miemczyk, S.; Hansbro, N.; Scandurra, G.; Britton, W. J.; Courant, T.; Dubois, P.; Collin, N.; Mohan, V. K.; Hansbro, P. M.; Wurm, M.; Wurm, F.; Steain, M.; Triccas, J.
10.1101/2024.11.06.622391 — immunology — Posted on 2024-11-07
3847 Impact of different synonymous codon substitution strategies on SARS-CoV-2 nucleocapsid protein expression in Escherichia coli
Bello, A. J.; Omotuyi, A. O.; Oladapo, O. B.; Adekunle, A. A.; UDECHIME, K. U.; Akinwande, A. B.; Odewale, A. F.; Adamson, O. O.; Eban, D. O.; Folarin, O.; Okpuzor, J.; Minari, J. B.
10.1101/2024.11.06.622014 — bioinformatics — Posted on 2024-11-07
3848 Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis
Li, J.; Wang, X.; Jordana, L.; Bonneil, E.; Ginestet, V.; Ahmed, M.; Bourouh, M.; Pascariu, C. M.; Schmeing, M.; Thibault, P.; Archambault, V.
10.1101/2024.10.07.617051 — cell biology — Posted on 2024-11-07
3851 A cross-species framework for investigating perceptual evidence accumulation
Chakravarty, S.; Delgado-Sallent, C.; Kane, G. A.; Xia, H.; Do, Q.; Senne, R. A.; Scott, B.
10.1101/2024.04.17.589945 — animal behavior and cognition — Posted on 2024-11-07
3852 Correction of RBFOX1 deficit rescues Huntington's disease mis-splicing and pathology
Lozano-Munoz, D.; Elorza, A.; Mayor-Fidalgo, L.; Santos-Galindo, M.; Lucas-Santamaria, M.; Parras, A.; Lucas, J. J.
10.1101/2024.11.06.622223 — neuroscience — Posted on 2024-11-07
3853 Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits
Pasquini, L.; Vohryzek, J.; Escrichs, A.; Sanz Perl, Y.; Alvarez, A.; Idesis, S.; Girn, M.; Roseman, L.; Mitchell, J. M.; Gazzaley, A.; Kringelbach, M.; Nutt, D. J.; Lyons, T.; Carhart-Harris, R. L.; Deco, G.
10.1101/2024.11.06.622302 — neuroscience — Posted on 2024-11-07
3856 CIFR (Clone-Integrate-Flip-out-Repeat): a toolset for iterative genome and pathway engineering of Gram-negative bacteria
Federici, F.; Luppino, F.; Aguilar-Vilar, C.; Mazaraki, M. E.; Petersen, L. B.; Ahonen, L.; Nikel, P. I.
10.1101/2024.11.07.622458 — synthetic biology — Posted on 2024-11-07
3857 The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas
Laurenge, A.; Pugliese, P.; Richard, Q.; Mathon, B.; Jouannet, S.; Hayat, Y.; Scuderi, S.; Marijon, P.; Labreche, K.; Alentorn, A.; Verreault, M.; Idbaih, A.; Birzu, C.; Huillard, E.; Pottier, N.; Desmons, A.; Fayache, I.; Kaas, G. A.; Kingsley, P. J.; Marnett, L. J.; Duplus, E.; El-Habr, E.; Salas, L. A.; Mokhtari, K.; Tran, S.; Touat, M.; Bielle, F.; Suva, M. L.; Iavarone, A.; Ceccarelli, M.; Mallat, M.; Sanson, M.; Castro-Vega, L. J.
10.1101/2024.08.23.608811 — cancer biology — Posted on 2024-11-07
3859 The acoustic properties, syllable structure, and syllable sequences of ultrasonic vocalizations (USVs) during neonatal opioid withdrawal in FVB/N mouse substrains
Wingfield, K. K.; Misic, T.; Miracle, S. A.; McDermott, C. S.; Jain, K.; Abney, N. M.; Richardson, K. T.; Rubman, M. B.; Beierle, J. A.; Wachman, E. M.; Bryant, C. D.
10.1101/2024.11.06.622304 — animal behavior and cognition — Posted on 2024-11-07
3861 The origins and functional significance of bivalve genome diversity
Liu, S.; Shi, C.; Chen, C.; Tan, Y.; Tian, Y.; Macqueen, D.; Li, Q.
10.1101/2024.09.09.611967 — genomics — Posted on 2024-11-07
3863 BMP4 is sufficient to induce a caudal organizer
Xu, P.-F.; Xing, Y.; Huang, Y.; Cheng, T.; Luo, T.; Dong, Y.; Jin, Z.; Tian, Y.; Liu, X.; Ma, J.; Ji, J.
10.1101/2024.11.07.622421 — developmental biology — Posted on 2024-11-07
3864 OXA beta-lactamases from Acinetobacter spp. are membrane-bound and secreted into outer membrane vesicles
Capodimonte, L.; Meireles, F. A.; Bahr, G.; Bonomo, R. A.; Dal Peraro, M.; Lopez, C.; Vila, A. J.
10.1101/2024.11.04.622015 — microbiology — Posted on 2024-11-07
3865 Direct RNA sequencing of the Escherichia coli epitranscriptome uncovers alterations under heat stress
Riquelme-Barrios, S.; Vasquez-Camus, L.; Cusack, S. A.; Burdack, K.; Plamenov Petrov, D.; Yesiltac-Tosun, G. N.; Kaiser, S.; Giehr, P.; Jung, K.
10.1101/2024.07.08.602490 — microbiology — Posted on 2024-11-07
3867 Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen
Solomon, A.; Bossel Ben-Moshe, N.; Hoffman, D.; Trzebanski, S.; Yehezkel, D.; Vainman, L.; Netea, M. G.; Avraham, R.
10.1101/2024.07.19.604264 — immunology — Posted on 2024-11-07
3868 Reducing CETP activity prevents memory decline in an Alzheimer's disease mouse model
Phenix, J.; Sarty, I.; Katz, M. S.; Nie, H.; Kerksiek, A.; Kiss, R. S.; Lütjohann, D.; Pastor, W. A.; Poirier, J.; Munter, L. M.; For the PREVENT-AD Research Group,
10.1101/2024.11.05.621935 — neuroscience — Posted on 2024-11-07
3869 Evaluating Synthetic Diffusion MRI Maps created with Diffusion Denoising Probabilistic Models
Chattopadhyay, T.; Ozarkar, S. S.; Jagad, C.; Joshy, N. A.; Buwa, K. S.; Thomopoulos, S. I.; Villalon-Reina, J. E.; Thompson, P. M.
10.1101/2024.11.06.621173 — neuroscience — Posted on 2024-11-07
3871 Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila.
Tassara, F. J.; Barella, M.; Simo, L.; Folgueira, M.; Rodriguez-Caron, M.; Ispizua, J. I.; Ellisman, M. H.; de la Iglesia, H. O.; Ceriani, M. F.; Gargiulo, J.
10.1101/2024.11.06.622263 — neuroscience — Posted on 2024-11-07
3874 Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson's disease model with Lewy-like pathology
Paschou, C.; Apokotou, O.; Kollias, A.; Charmpi, K.; Dede, S.; Samiotaki, M.; Palese, F.; Dimoula, K.; Emmanouilidou, E.; Taoufik, E.; Zurzolo, C.; Matsas, R.; Papastefanaki, F.
10.1101/2024.11.06.621638 — neuroscience — Posted on 2024-11-07
3875 Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve
Laurienti, P. J.; Kritchevsky, S. B.; Lyday, R. G.; Miller, M. E.; Lockhart, S. N.; Rundle, M. M.; Hugenschmidt, C. E.; Burdette, J. H.; Shappell, H. M.; Chen, H.; Baker, L. D.; Neyland, B. R.; Holtzer, R.
10.1101/2024.11.07.622257 — neuroscience — Posted on 2024-11-07
3878 Gut Microbiota Regulates Exercise-induced Hormetic Modulation of Cognitive Function
Cintado, E.; Muela, P.; Martin Rodriguez, L.; Alcaide, I.; Vlckova, K.; Valderrama, B.; Bastiaanssen, T. F.; Tezanos, P.; Rodriguez-Munoz, M.; de Ceballos, M. L.; Aburto, M. R.; Cryan, J.; Trejo, J. L.
10.1101/2024.11.07.621818 — neuroscience — Posted on 2024-11-07
3879 Personalized tDCS targeting visual motion area V5 modulates smooth pursuit initiation
Radecke, J.-O.; Kuehn, A.; Erdbruegger, T.; Buschermoehle, Y.; Rashidi, S.; Stoeckler, H.; Sack, B.; Borgwardt, S.; Schneider, T. R.; Gross, J.; Wolters, C. H.; Sprenger, A.; Lencer, R.
10.1101/2024.11.06.622280 — neuroscience — Posted on 2024-11-07
3880 Cocaine, via ΔFosB, remodels gene expression and excitability in ventral hippocampus
Eagle, A. L.; Doyle, M. A.; Sugimoto, C.; Dykstra, M. M.; Kuhn, H. M.; Murray, B. R.; Bastle, R. M.; He, J.; Maze, I.; Mazei-Robison, M.; Robison, A. J.
10.1101/2024.11.06.621895 — neuroscience — Posted on 2024-11-07
3881 Sex differences in the impact of nerve injury on Locus Coeruleus function and behaviour in mice
Mariscal, P.; Martinez-Cortes, A.; Llorca-Torralba, M.; Razquin, J.; Miguelez, C.; Ulecia-Moron, C.; Garcia-Bueno, B.; Leza, J. C.; Bravo, L.; Berrocoso, E.
10.1101/2024.11.06.622052 — neuroscience — Posted on 2024-11-07
3882 A chill brain-music interface for enhancing music chills with personalized playlists
Kondoh, S.; Etani, T.; Sakakibara, Y.; Naruse, Y.; Imamura, Y.; Ibaraki, T.; Fujii, S.
10.1101/2024.11.07.621657 — neuroscience — Posted on 2024-11-07
3883 Differentiating hallucination proneness dimensions through resting state alpha dynamics
Honcamp, H.; O'Donnell, P.; Pinheiro, A. P.; Trujillo-Barreto, N. J.; Schwartze, M.; El-Deredy, W.; Kotz, S. A.
10.1101/2024.11.06.622288 — neuroscience — Posted on 2024-11-07
3885 Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Park, J.; Sipe, G. O.; Tang, X.; Ojha, P.; Fernandes, G.; Leow, Y. N.; Zhang, C.; Osako, Y.; Natesan, A.; Drummond, G. T.; Jaenisch, R.; Sur, M.
10.1101/2024.11.06.622321 — neuroscience — Posted on 2024-11-07
3888 Unifying Subicular Function: A Predictive Map Approach
Bennett, L.; de Cothi, W.; Muessig, L.; Ribeiro Rodrigues, F.; Cacucci, F.; Wills, T.; Sun, Y.; Giocomo, L. M.; Lever, C.; Poulter, S.; Barry, C.
10.1101/2024.11.06.622306 — neuroscience — Posted on 2024-11-07
3889 Olfactory bulb tracks breathing rhythms and place in freely behaving mice
Sterrett, S. C.; Findley, T. M.; Rafilson, S. E.; Brown, M. A.; Weible, A. P.; Marsden, R.; Tarvin, T.; Wehr, M.; Murray, J. M.; Fairhall, A. L.; Smear, M. C.
10.1101/2024.11.06.622362 — neuroscience — Posted on 2024-11-07
3892 Ultrastructural correlates of circadian structural plasticity
Ispizua, J. I.; Rodriguez-Caron, M.; Tassara, F. J.; Keun-young, K.; Perkins, C. I.; Barzi, M.; Carpio-Romero, C.; Hansen, C. N.; Gargiulo, J.; Rosato, E.; de la iglesia, H.; Ellisman, M.; Ceriani, M. F.
10.1101/2024.11.06.622332 — neuroscience — Posted on 2024-11-07
3893 Axonal injury signaling is restrained by a spared synaptic branch
Smithson, L. J.; Zang, J. L.; Junginger, L.; Waller, T. J.; Reilly-Jankowiak, L.; Khan, S.; Li, Y.; Cai, D.; Collins, C. A.
10.1101/2024.11.07.622420 — neuroscience — Posted on 2024-11-07
3896 SMAS: Structural MRI-Based AD Score using Bayesian VAE
Nemali, A.; Bernal, J.; Yakupov, R.; Singh, D.; Dyrba, M.; Incesoy, E.; Mukherjee, S.; Peters, O.; Hellmann, J.; Ersoezlue, E.; Preis, L.; Priller, J.; Spruth, E.; Altenstein, S.; Lohse, A.; Schneider, A.; Fliessbach, K.; Kimmich, O.; Wiltfang, J.; Hansen, N.; Schott, B.; Rostamzadeh, A.; Glanz, W.; Butryn, M.; Buerger, K.; Janowitz, D.; Ewers, M.; Perneczky, R.; Rauchmann, B.; Teipel, S.; Kilimann, I.; Goerss, D.; Laske, C.; Sodenkamp, S.; Spottke, A.; Coenjaerts, M.; Brosseron, F.; Luesebrink, F.; Dechent, P.; Scheffler, K.; Hetzer, S.; Kleineidam, L.; Stark, M.; Jessen, F.; Duezel, E.; Zieg
10.1101/2024.11.07.622411 — neuroscience — Posted on 2024-11-07
3897 Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions
Kong, E.; Zabeh, E.; Liao, Z.; Mihaila, T. S.; Peterka, D. S.; Wilson, C.; Santhirasegaran, C.; Losonczy, A.; Geiller, T.
10.1101/2024.11.07.622379 — neuroscience — Posted on 2024-11-07
3898 Opposing effects of rewarding and aversive stimuli on D1 and D2 types of dopamine-sensitive neurons in the central amygdala
Bijoch, L.; Wisniewska, J.; Szczypkowski, P.; Pawlowska, M.; Hajdukiewicz, K.; Lapkiewicz, R.; Beroun, A.
10.1101/2024.11.07.622413 — neuroscience — Posted on 2024-11-07
3899 Rapid fluctuations in histamine associated with intake of nutritive and non-nutritive solutions
Volcko, K. L.; Gresch, A.; Benowitz, B.; Taghipourbibalan, H.; Visser, M.; Stuber, G. D.; Gordon-Fennell, A. G.; Patriarchi, T. E.; McCutcheon, J. E.
10.1101/2024.11.07.622425 — neuroscience — Posted on 2024-11-07
3900 Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm
Isherwood, S. J. S.; Kemp, S. A.; Miletic, S.; Stevenson, N.; Bazin, P.-L.; Forstmann, B.
10.1101/2023.06.06.543900 — neuroscience — Posted on 2024-11-07
3901 Outer hair cells stir cochlear fluids
Lee, C.; Shokrian, M.; Henry, K. S.; Carney, L.; Holt, J. C.; Nam, J.-H.
10.1101/2024.08.07.607009 — neuroscience — Posted on 2024-11-07
3903 Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
Sun, Y.; Li, C.; Deng, X.; Li, W.; Deng, X.; Ge, W.; Shi, M.; Guo, Y.; Yu, Y. V.; Zhou, H.-b.; Jin, Y. N.
10.1101/2024.09.06.611731 — pharmacology and toxicology — Posted on 2024-11-07
3908 Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells
Chen, Y.-C.; Takada, M.; Nagornyuk, A.; Muhan, W.; Yamada, H.; Nagashima, T.; Ohtsuka, M.; DeLuca, J. G.; Markus, S. M.; Takaku, M.; Suzuki, A.
10.1101/2024.11.04.621816 — cancer biology — Posted on 2024-11-07
3909 Induction of pluripotent oncogenic stem cells from mouse fibroblasts
Shabrish, S.; Devi, N. L.; Mohanty, S.; Kumar, R.; Lopes, R.; Akhter, N.; Khare, N. K.; Raghuram, G. V.; Jadhav, V.; Shinde, S.; Chandrani, P.; Mittra, I.
10.1101/2024.11.06.622204 — cancer biology — Posted on 2024-11-07
3910 Biases in the Parsortix system observed with pancreatic cancer cell lines
Vandenbussche, N.; Imschoot, R.; Lintermans, B.; Denolf, L.; Taminau, J.; Fieuws, C.; Berx, G.; Gevaert, K.; Claes, K. B. M.
10.1101/2024.11.05.621344 — cancer biology — Posted on 2024-11-07
3911 Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy
Samarin, J.; Nuskova, H.; Fabrowski, P.; Malz, M.; Amtmann, E.; Taeubert, M. J.; Pastor-Flores, D.; Kazdal, D.; Kurilov, R.; Deis, F.; Pink, H.; Hummel-Eisenbeiss, J.; deVries, N.; Kaushal, K.; Dick, T.; Hamilton, G.; Muckenthaler, M.; Mall, M.; Lim, B.; Kanamaru, T.; Klinke, G.; Sos, M.; Frede, J.; Miller, A.; Alborzinia, H.; Gunkel, N.
10.1101/2024.11.06.621846 — cancer biology — Posted on 2024-11-07
3912 NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer
Zhao, S.; Lin, J.; Zhu, B.; Jin, Y.; Dong, Q.; Ruan, X.; Jin, D.; Yi, Y.; Bai, B.; Li, H.; Liang, D.; Lu, J.; Meng, L.; Wang, X.; Cui, Y.; Gu, Y.; Shen, X.; Lu, X.; Rao, S.; Sun, W.
10.1101/2024.11.05.622078 — cancer biology — Posted on 2024-11-07
3913 Lifetime brain atrophy estimated from a single MRI: measurement characteristics and genome-wide correlates
Fürtjes, A. E.; Foote, I. F.; Xia, C.; Davies, G.; Moodie, J. E.; Taylor, A.; Liewald, D.; Redmond, P.; Corley, J.; McIntosh, A. M.; Whalley, H. C.; Maniega, S. M.; Hernandez, M. D. V.; Backhouse, E.; Ferguson, K.; Bastin, M. E.; Wardlaw, J.; de la Fuente, J.; Grotzinger, A. D.; Luciano, M.; Hill, W. D.; Deary, I. J.; Tucker-Drob, E. M.; Cox, S. R.
10.1101/2024.11.06.622274 — genetics — Posted on 2024-11-07
3915 Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors
Bamidele, N.; Ansodaria, A.; Chen, Z.; Cheng, H.; Panwala, R.; Jazbec, E.; Sontheimer, E. J.
10.1101/2024.10.30.620986 — molecular biology — Posted on 2024-11-07
3917 Seasonal patterns of exometabolites depend on microbial functions in the oligotrophic ocean
McParland, E. L.; Wittmers, F.; Bolanos, L. M.; Carlson, C. A.; Curry, R.; Giovannoni, S. J.; Michelsen, M.; Parsons, R. J.; Kido Soule, M. C.; Swarr, G. J.; Temperton, B.; Vergin, K.; Worden, A. Z.; Longnecker, K.; Kujawinski, E. B.
10.1101/2024.03.05.583599 — microbiology — Posted on 2024-11-07
3918 Cell attachment and tail contraction of S. aureus phage phi812
Binovsky, J.; Siborova, M.; Novacek, J.; Bardy, P.; Baska, R.; Skubnik, K.; Botka, T.; Benesik, M.; Pantucek, R.; Tripsianes, K.; Plevka, P.
10.1101/2024.09.19.613683 — microbiology — Posted on 2024-11-07
3925 Impaired humidity sensing reduces tick survival by preventing water homeostasis
Uhran, M. R.; Onyeagba, K.; Sanderson, S. M.; Hoque, S. F.; Kelley, M.; Smith, E. S.; Oyen, K.; Benton-Anderson, A.; Arya, T.; Ledezma, A.; Kennedy, J.; Frigard, R.; Holmes, C. J.; Chen, S.-C.; Olafson, P. U.; Gaff, H. D.; Benoit, J. B.
10.1101/2024.11.06.618166 — physiology — Posted on 2024-11-07
3926 Multiple lineages of transmissible neoplasia in the basket cockle (Clinocardium nuttallii) with repeated horizontal transfer of mitochondrial DNA
Yonemitsu, M. A.; Sevigny, J. K.; Vandepas, L. E.; Dimond, J. L.; Giersch, R. M.; Gurney-Smith, H. J.; Abbott, C. L.; Supernault, J.; Withler, R.; Smith, P. D.; Weinandt, S. A.; Garrett, F. E.; Child, Z. J.; Sigo, R. L.; Unsell, E.; Crim, R. N.; Metzger, M. J.
10.1101/2023.10.11.561945 — cancer biology — Posted on 2024-11-07
3933 PLM-interact: extending protein language models to predict protein-protein interactions
Liu, D.; Young, F.; Lamb, K. D.; Claudio Quiros, A.; Pancheva, A.; Miller, C.; Macdonald, C.; Robertson, D. L.; Yuan, K.
10.1101/2024.11.05.622169 — bioinformatics — Posted on 2024-11-07
3934 Understanding responses to multi-electrode epiretinal stimulation using a biophysical model
Vilkhu, R. S.; Vasireddy, P. K.; Kish, K. E.; Gogliettino, A. R.; Lotlikar, A.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Mitra, S.; Chichilnisky, E. J.
10.1101/2024.08.20.608829 — bioengineering — Posted on 2024-11-07
3935 Genomes of Poaceae sisters reveal key metabolic innovations preceding the emergence of grasses
Takeda-Kimura, Y.; Moore, B.; Holden, S.; Deb, S. K.; Barrett, M.; Lorence, D.; de Oliveira, M. V. V.; Grimwood, J.; Williams, M.; Boston, L. B.; Jenkins, J. W.; Plott, C.; Shu, S.; Barry, K. W.; Goodstein, D. M.; Schmutz, J.; Moscou, M. J.; McKain, M. R.; Leebens-Mack, J. H.; Maeda, H. A.
10.1101/2024.11.06.622220 — genomics — Posted on 2024-11-07
3937 Cephalopod Sex Determination and its Ancient Evolutionary Origin
Coffing, G. C.; Tittes, S.; Small, S. T.; Songco-Casey, J. O.; Piscopo, D. M.; Pungor, J. R.; Miller, A. C.; Niell, C.; Kern, A. D.
10.1101/2024.02.21.581452 — evolutionary biology — Posted on 2024-11-07
3939 Evolution of vocal production learning in parrots
Krasheninnikova, A.; Smeele, S. Q.; Snijders, M.; Haldar, E.; Carpenter, J.; Zamora, R.; Naguib, M.; Wolf, J. B. W.; Gahr, M.; von Bayern, A. M.
10.1101/2024.11.05.622162 — evolutionary biology — Posted on 2024-11-07
3943 Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis
Qin, G.; Zhao, Q.; Fujita, A.; Damiani, I.; Easwaran, M.; Basu, S.; Gu, W.; Li, D. Y.; Worssam, M.; Palmisano, B.; Monteiro, J. P.; Ramste, M.; Kundu, R.; Nguyen, T.; Park, C.; Weldy, C. S.; Cheng, P. C.; Kim, J. B.
10.1101/2024.09.24.614572 — molecular biology — Posted on 2024-11-07
3944 Spatial mapping of dextran sodium sulphate-induced intestinal inflammation and its systemic effects
Adams, L.; Rasid, O.; Hulme, H.; Quon, T.; Burchmore, R.; Milling, S.; Goodwin, R.; Wall, D. M.
10.1101/2024.04.26.591292 — molecular biology — Posted on 2024-11-07
3945 Hantaan virus-derived peptides that stabilize HLA-E could abrogate inhibition of CD56dimNKG2A+ NK cells
Manling, X.; Kang, T.; Yusi, Z.; Xiaoyue, X.; Chunmei, Z.; Jiajia, Z.; Fenglan, W.; Xiyue, Z.; Xuyang, Z.; Ran, Z.; Yun, Z.; Boquan, J.; Ma, Y.
10.1101/2024.11.05.622026 — immunology — Posted on 2024-11-07
3946 Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression
Aboharb, F.; Davoudian, P. A.; Shao, L.-X.; Liao, C.; Rzepka, G. N.; Wojtasiewicz, C.; Dibbs, M.; Rondeau, J.; Sherwood, A. M.; Kaye, A. P.; Kwan, A. C.
10.1101/2024.05.23.590306 — neuroscience — Posted on 2024-11-07
3947 TIA1 Mediates Divergent Inflammatory Responses to Tauopathy in Microglia and Macrophages
Webber, C. J.; Van Der Spek, S.; Cruz, A. L. F.; Puri, S.; Zhang, C.; Aw, J. T. M.; Papadimitriou, G.-Z.; Roberts, R.; Jiang, K.; Tran, T. N.; Zhang, L.; Taylor, A. K.; Wang, Z.; Porter, J.; Sotiropoulos, I.; Emili, A.; Silva, J. M.; Li, H.; Wolozin, B.
10.1101/2024.11.06.622325 — neuroscience — Posted on 2024-11-07
3948 Human cerebellum and ventral tegmental area interact during extinction of learned fear
Nio, E.; Pereira, P. P.; Diekmann, N.; Petrenko, M.; Doubliez, A.; Ernst, T. M.; Batsikadze, G.; Maderwald, S.; Deuschl, C.; Uengoer, M.; Cheng, S.; Merz, C. J.; Quick, H. H.; Timmann, D.
10.1101/2024.11.06.622063 — neuroscience — Posted on 2024-11-07
3949 An Infralimbic Cortex Neuronal Ensemble Encoded During Learning Attenuates Fear Generalization Expression
Subramanian, R.; Bauman, A.; Carpenter, O.; Cho, C.; Coste, G.; Dam, A.; Drake, K.; Ehnstrom, S.; Fitzgerald, N.; Jenkins, A.; Koolpe, H.; Liu, R.; Paserman, T.; Petersen, D.; Chavez, D. S.; Rozental, S.; Thompson, H.; Tsukuda, T.; Zweig, S.; Gall, M.; Zupan, B.; Bergstrom, H.
10.1101/2024.08.18.608308 — neuroscience — Posted on 2024-11-07
3952 A high-quality genome of the mass-blooming desert plant Cistanthe longiscapa and its photosynthetic behavior related to drought and life history
Chomentowska, A.; Raimondeau, P.; Wei, L.; Jose, E. G. D.; Dauerman, S. G.; Davis, V. Z.; Moreira-Munoz, A.; Peralta, I. E.; Edwards, E. J.
10.1101/2024.11.06.622337 — plant biology — Posted on 2024-11-07
3953 A multidisciplinary on-farm survey of maize-bean intercropping highlights key considerations for reviving traditional agricultural systems.
Vazeux-Blumental, N.; Mathieu, L.; Trabac, T.; Palaffre, C.; Lagardere, B.; Carraretto, M.; Bauland, C.; Le Guilloux, M.; Paysant-Le Roux, C.; Caius, J.; Marmagne, A.; Enjalbert, J.; Flutre, T.; Le Cadre, E.; Parnaudeau, V.; Muller, D.; Moenne-Loccoz, Y.; Manicacci, D.; Tenaillon, M. I.
10.1101/2024.04.24.590929 — plant biology — Posted on 2024-11-07
3954 Ethanol reduces grapevine water consumption by limiting transpiration
Ait Kaci, N.; Diot, A.; Quinquiry, B.; Yobregat, O.; Pellegrino, A.; Maury, P.; Chervin, C.
10.1101/2024.08.31.610611 — plant biology — Posted on 2024-11-07
3955 AI-readiness for Biomedical Data: Bridge2AI Recommendations
Clark, T.; Caufield, H.; Parker, J. A.; Al Manir, S.; Amorim, E.; Eddy, J.; Gim, N.; Gow, B.; Goar, W.; Haendel, M.; Hansen, J. N.; Harris, N.; Hermjakob, H.; McWeeney, S. K.; Nebeker, C.; Nikolov, M.; Shaffer, J.; Sheffield, N.; Sheynkman, G.; Stevenson, J.; Mungall, C.; Chen, J. Y.; Wagner, A.; Kong, S. W.; Ghosh, S. S.; Patel, B.; Williams, A.; Munoz-Torres, M. C.
10.1101/2024.10.23.619844 — bioinformatics — Posted on 2024-11-07
3960 Archaic Adaptive Introgression in Modern Human Reproductive Genes
Kendall, C. J. R.; Nooranikhojasteh, A.; Parra, E.; Schillaci, M. A.; Viola, B.
10.1101/2024.11.06.622331 — evolutionary biology — Posted on 2024-11-07
3968 Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction
Ihara, J.; Huang, Y.; Takami, Y.; Nozato, Y.; Takahashi, T.; Kakino, A.; Wang, C.; Wang, Z.; Guo, Y.; Liu, W.; Yin, N.; Ohara, R.; Fujimoto, T.; Yoshida, S.; Hongyo, K.; Koriyama, H.; Akasaka, H.; Takeshita, H.; Sakai, S.; Inoue, K.; Isaka, Y.; Rakugi, H.; Sawamura, T.; Yamamoto, K.
10.1101/2024.05.13.594020 — molecular biology — Posted on 2024-11-07
3971 Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice
Freytag, D.; Giorgiutti, S.; Wadier, N.; Depauw, S.; Hopsomer, G.; Mertz, P.; Auge, F.; Carapito, R.; Couillin, I.; Korganow, A.-S.; Pala, F.; Bosticardo, M.; Notarangelo, L.; rieux-laucat, f.; Riteau, N.; Kirstetter, P.; Soulas-Sprauel, P.
10.1101/2024.11.01.621470 — immunology — Posted on 2024-11-07
3973 When Little Means a Lot: Impact of a Brief Early-life Motor Training on Mouse Neuromuscular Development.
Quilgars, C.; Boue;-Grabot, E.; De Deurwaerdere, P.; Cazalets, J.-R.; PERRIN, F. E.; Bertrand, S. S.
10.1101/2024.11.06.622218 — neuroscience — Posted on 2024-11-07
3974 A sensitive period for the development of episodic-like memory in mice
Ramsaran, A. I.; Ventura, S.; Gallucci, J.; De Snoo, M. L.; Josselyn, S. A.; Frankland, P. W.
10.1101/2024.11.06.622296 — neuroscience — Posted on 2024-11-07
3975 A Prefrontal Cortex Map based on Single Neuron Activity
Le Merre, P.; Heining, K.; Slashcheva, M.; Jung, F.; Moysiadou, E.; Guyon, N.; Yahya, R.; Park, H.; Wernstal, F.; Carlen, M.
10.1101/2024.11.06.622308 — neuroscience — Posted on 2024-11-07
3976 Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects
Zequeira, S.; Gazarov, E. A.; Güvenli, A. A.; Berthold, E. C.; Senetra, A. S.; Febo, M.; Hiranita, T.; McMahon, L. R.; Sharma, A.; McCurdy, C. R.; Setlow, B.; Bizon, J. L.
10.1101/2024.09.26.615028 — neuroscience — Posted on 2024-11-07
3977 The Infraslow Fluctuation of Sigma Power During Sleep: Links to Markers of Arousal and Memory Reactivation Across Development
Dimitriades, M. E.; Osorio-Forero, A.; Fattinger, S.; von Arx, S.; Kurth, S.; Pugin, F.; Jaramillo, V.; Volk, C.; Krugliakova, E.; Furrer, M.; Leach, S.; Achermann, P.; Gerstenberg, M.; Huber, R.
10.1101/2024.11.06.620875 — neuroscience — Posted on 2024-11-07
3979 Deciphering gene regulatory programs underlying functionally divergent naive T cell subsets
Zhu, H.; Jiang, Y.; McNairn, A. J.; Fogarty, E. A.; Tabilas, C.; Patel, R. K.; Chobirko, J. D.; Munn, P. R.; Smith, N. L.; Grenier, J. K.; Rudd, B. D.; Grimson, A.
10.1101/2024.11.06.621737 — systems biology — Posted on 2024-11-07
3980 Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
Gui, F.; Jiang, B.; Jiang, J.; He, Z.; Tsujino, T.; Takai, T.; Arai, S.; Pana, C.; Koellermann, J.; Bradshaw, G. A.; Eisert, R.; Kalocsay, M.; Fassl, A.; Balk, S. P.; Kibel, A. S.; Jia, L.
10.1101/2024.07.09.602803 — cancer biology — Posted on 2024-11-07
3981 Breast cancer cells promote osteoclast differentiation in an MRTF-dependent paracrine manner
Chawla, P.; Sharma, I.; Gau, D.; Eder, I.; Chen, F.; Yu, V.; Welling, N.; Boone, D.; Taboas, J.; LEE, A. V.; Larregina, A.; Galson, D. L.; Roy, P.
10.1101/2023.12.06.570453 — cancer biology — Posted on 2024-11-07
3982 Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography
Hollingworth, D.; Herold, K. F.; Kelly, G.; Mykhaylyk, V. B.; Xiang, J.; Zhang, D.; Wallace, B. A.; Hemmings, H. C.
10.1101/2024.11.04.621342 — biophysics — Posted on 2024-11-07
3984 Reproducible processing of TCGA regulatory networks
Fanfani, V.; Shutta, K. H.; Mandros, P.; Fischer, J.; Saha, E.; Micheletti, S.; Chen, C.; Ben Guebila, M.; Lopes-Ramos, C. M.; Quackenbush, J.
10.1101/2024.11.05.622163 — bioinformatics — Posted on 2024-11-07
3986 Metapredict enables accurate disorder prediction across the Tree of Life
Lotthammer, J. M.; Hernandez-Garcia, J.; Griffith, D.; Weijers, D.; Holehouse, A. S.; Emenecker, R. J.
10.1101/2024.11.05.622168 — bioinformatics — Posted on 2024-11-07
3988 Annotation and assessment of functional variants in regulatory regions using epigenomic data in farm animals
Ma, R.; Kuang, R.; Zhang, J.; Sun, J.; Xu, Y.; Zhou, X.; Han, Z.; Hu, M.; Wang, D.; Luan, Y.; Fu, Y.; Zhang, Y.; Li, X.; Zhu, M.; Xiang, T.; Zhao, S.; Shi, M.; Zhao, Y.
10.1101/2024.02.06.578787 — genomics — Posted on 2024-11-07
3990 Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility
Debaenst, S.; Jarayseh, T.; De Saffel, H.; Bek, J. W.; Boone, M.; Josipovic, I.; Kibleur, P.; Kwon, R. Y.; Coucke, P.; Willaert, A.
10.1101/2024.06.27.601074 — genetics — Posted on 2024-11-07
3992 The neural mechanisms of concept formation over time in music
Bonetti, L.; Fernandez-Rubio, G.; Szabo, S. A.; Carlomagno, F.; Vuust, P.; Kringelbach, M. L.; Brattico, E.
10.1101/2024.11.06.622228 — neuroscience — Posted on 2024-11-07
3993 Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA
Kania, E. E.; Fenix, A.; Marciniak, D. M.; Lin, Q.; Bianchi, S.; Hristov, B.; Li, S.; Camplisson, C. K.; Fields, R.; Beliveau, B. J.; Schweppe, D. K.; Noble, W. S.; Ong, S.-E.; Bertero, A.; Murry, C. E.; Shechner, D. M.
10.1101/2024.11.05.622011 — genomics — Posted on 2024-11-06
3994 Deaminase-assisted single-molecule and single-cell chromatin fiber sequencing
Swanson, E. G.; Mao, Y.; Mallory, B. J.; Vollger, M. R.; Ranchalis, J.; Bohaczuk, S. C.; Parmalee, N. L.; Bennett, J. T.; Stergachis, A. B.
10.1101/2024.11.06.622310 — genomics — Posted on 2024-11-06
3995 Methuselah Proteins in Longevity: Unraveling Their Impact Through Mathematical Genomics
Hassan, S. S.; NAWN, D.; Ghosh, A.; Sil, M.; GOSWAMI, A.; Basu, P.; Lundstrom, K.; Uversky, V. N.
10.1101/2024.11.03.621698 — genomics — Posted on 2024-11-06
3997 Defining the genetic determinants of CD8+ T cell receptor repertoire in the context of immune checkpoint blockade
Ng, E.; Tong, O.; Taylor, C. A.; Watson, R. A.; Sun, B.; Milotay, G.; Mackay, S.; Gilchrist, J.; Little, M.; Fairfax, B. P.; Luo, Y.
10.1101/2024.11.04.618564 — genetics — Posted on 2024-11-06
4004 The maize recombination landscape evolved during domestication.
Epstein, R.; Wheeler, J.; Hubisz, M.; Sun, Q.; Bukowski, R.; Zhai, J.; Lai, W.-Y.; Buckler, E. S.; Pawlowski, W. P.
10.1101/2024.11.04.621928 — evolutionary biology — Posted on 2024-11-06
4005 Hallmarks of uterine receptivity predate placental mammals
Basanta, S.; Stadtmauer, D. J.; Maziarz, J. D.; McDonough-Goldstein, C. E.; Cole, A. G.; Dagdas, G.; Wagner, G. P.; Pavlicev, M.
10.1101/2024.11.04.621939 — evolutionary biology — Posted on 2024-11-06
4008 Novel wheat germ agglutinin-based mass cytometry cell barcoding reagent for heterogeneous, live or fixed sample
Hannan, R. T.; Barker, D.; Cox, B. P.; Roosa, C. A.; Harper, T. A.; Solga, M. D.; Griffin, D. R.; Sturek, J. M.
10.1101/2024.11.05.618916 — cell biology — Posted on 2024-11-06
4009 CXXC5 is a ubiquitinated protein and is degraded by the ubiquitination-proteasome pathway
Ayten, H.; Toker, P.; Turan, G.; Olgun, C. E.; Demiralay, O. D.; Binarci, B.; Gupur, G.; Yasar, P.; Akman, H. B.; Haberkant, P.; Muyan, M.
10.1101/2024.11.06.622249 — cell biology — Posted on 2024-11-06
4010 L-lactic acid induces short- and long-term cardioprotective effects through MCT1 transport, induction of metabolic reprogramming, and gene expression modulation.
Cler, M.; Perez-Amodio, S.; Valls-Lacalle, L.; MARTINEZ, E.; Barba, I.; Ganse, F. G.; Nicastro, L.; Terracciano, C.; Rodriguez Sinovas, A.; Engel, E.
10.1101/2024.11.05.621926 — cell biology — Posted on 2024-11-06
4012 Effects of Aging on the Immune and Periosteal Response to Fracture in Mice
King, J. S.; Wan, M.; Kim, A.; Novak, S.; Prabhu, S.; Kalajzic, I.; Delany, A. M.; Sanjay, A.
10.1101/2024.11.06.622348 — cell biology — Posted on 2024-11-06
4015 Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes
Aseem, S. O.; Way, G.; Wang, J.; Zhao, D.; Tai, Y.-L.; Gurley, E.; Zeng, J.; Wang, X.; Hylemon, P. B.; Huebert, R. C.; Sanyal, A. J.; Zhou, H.
10.1101/2024.11.06.621880 — cell biology — Posted on 2024-11-06
4017 Bidirectional Peptide Conformation Prediction for MHC Class II using PANDORA
Rademaker, D. T.; Parizi, F. M.; van Vreeswijk, M.; Eerden, S.; Marzella, D.; Xue, L.
10.1101/2024.11.04.621877 — immunology — Posted on 2024-11-06
4018 Effect of heme oxygenase-1 on the expression of interferon-stimulated genes
Chudy, P.; Bednarczyk, K.; Chatian, E.; Krzeptowski, W.; Szade, A.; Szade, K.; Zukowska, M.; Wolnik, J.; Sokolowski, G.; Jozkowicz, A.; Nowak, W. N.
10.1101/2024.11.04.620611 — immunology — Posted on 2024-11-06
4024 EXOSOMES FROM CYCLIC MICE MODULATE LIVER TRANSCRIPTOME IN ESTROUPAUSE MICE INDEPENDENT OF AGE
Zanini, B.; Hense, J.; Garcia, D.; Ashiqueali, S.; Alves, P.; Oliveira, T.; Collares, T.; Brieno-Enriquez, M. A.; Mason, J.; Masternak, M. M.; Schneider, A.
10.1101/2024.11.04.621842 — physiology — Posted on 2024-11-06
4027 Disconnect between in vitro and in vivo efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma
de Gooijer, M. C.; Zhang, P.; Buil, L. C. M.; Citirikkaya, C. H.; Colakoglu, H.; Maia, A. R. R.; Bockaj, I.; Espitia-Ballestas, M.; Kuil, L. E.; Beijnen, J. H.; van Tellingen, O.
10.1101/2024.11.04.621827 — cancer biology — Posted on 2024-11-06
4028 Chlorpyrifos induces lung metastases and modulation of cancer stem cell markers in triple negative breast cancer model
Lasagna, M.; Mardirosian, M.; Zappia, C. D.; Enriquez, L.; Miret, N.; Dahir, L.; Zotta, E.; Randi, A.; Nunez, M.; Cocca, C.
10.1101/2024.11.04.621565 — cancer biology — Posted on 2024-11-06
4029 Tenascin-C potentiates Wnt signaling in thyroid cancer
Hartmann, H. A.; Loberg, M. A.; Xu, G. J.; Schwarzkopf, A. C.; Chen, S.-C.; Phifer, C. J.; Caroland, K.; Chen, H.-C.; Diaz, D.; Tigue, M. L.; Hesterberg, A. B.; Gallant, J.-N.; Shaddy, S. M.; Sheng, Q.; Netterville, J. L.; Rohde, S. L.; Solorzano, C. C.; Bischoff, L. A.; Baregamian, N.; Hurley, P. J.; Murphy, B. A.; Choe, J. H.; Huang, E. C.; Ye, F.; Lee, E.; Weiss, V. L.
10.1101/2024.11.04.621959 — cancer biology — Posted on 2024-11-06
4030 Towards a standardised method for the characterisation and isolation of colorectal cancer stem cells by SdFFF and UHF-DEP: highlighted by transcriptomic analysis
JEMFER, C.; BLASCO, N.; Durand, S.; Blin, E.; Mas, R.; BASLY, I.; Boutaud, M.; Daverat, H.; Pothier, A.; Dalmay, C.; Mathonnet, M.; Begaud, G.; BATTU, S.
10.1101/2024.11.04.621916 — cancer biology — Posted on 2024-11-06
4032 Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer
Zhang, Y.; Wang, H.; Wei, Y.; Pan, Y.; Song, X.; Shi, T.; Shao, J.; Yu, L.; Liu, B.; Wang, Y.; Wei, J.
10.1101/2024.11.04.621870 — cancer biology — Posted on 2024-11-06
4033 Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability
Joshi, K.; Suvilesh, K. N.; Natesh, N. S.; Manjunath, Y.; Coberly, J.; Schlink, S.; Kunin, J. R.; Prather, R. S.; Whitworth, K.; Nelson, B.; Bryan, J.; Hoffman, T.; Golzy, M.; Raju, M.; Teixeiro, E.; Telugu, B. P.; Kaifi, J. T.; Rachagani, S.
10.1101/2024.11.04.621940 — cancer biology — Posted on 2024-11-06
4039 Actin turnover and myosin contractility determine emergent Thickness Robustness of Cell-Mimicking Cortex
Gat, S.; Amit, Y.; Livne, G.; Sanchez, D. S.; Porat, N.; Yochelis, A.; Gov, N.; Bernheim-Groswasser, A.
10.1101/2024.11.04.621887 — biophysics — Posted on 2024-11-06
4044 Benchmarking Self-Supervised Learning for Single-Cell Data
Toma, P.; Ovcharenko, O.; Daunhawer, I.; Vogt, J.; Barkmann, F.; Boeva, V.
10.1101/2024.11.04.620867 — bioinformatics — Posted on 2024-11-06
4045 mcBERT: Patient-Level Single-cell Transcriptomics Data Representation
Querfurth, B. v.; Lohmoeller, J.; Pennekamp, J.; Bleckwehl, T.; Kramann, R.; Wehrle, K.; Hayat, S.
10.1101/2024.11.04.621897 — bioinformatics — Posted on 2024-11-06
4048 Biosynth Pipeline: An integrated platform for merging the computational design of chimeric type I polyketide synthases with enzymatic pathways for chemical biosynthesis
Chainani, Y.; Diaz, J.; Guilarte-Silva, M.; Blay, V.; Tyo, K.; Broadbelt, L. J.; Mukhopadhyay, A.; Keasling, J. D.; Martin, H. G.; Backman, T. W. H.
10.1101/2024.11.04.621673 — bioinformatics — Posted on 2024-11-06
4049 PAIRWISE: Deep Learning-based Prediction of Effective Personalized Drug Combinations in Cancer
Xu, C.; US, I.; Cohen-Setton, J.; Milo, M.; Sidders, B.; Fitzgibbon, J.; Melnick, A.; Pan, H.; Elemento, O.; Bulusu, K.
10.1101/2024.11.04.621884 — bioinformatics — Posted on 2024-11-06
4051 Stage-specific gene ratios highlight genes and mechanisms related to presymptomatic and symptomatic Multiple Myeloma
Georgiou, G.; Minadakis, G.; Karathanasis, N.; Savva, K.; Athieniti, E.; Bourdakou, M. M.; Spyrou, G. M.
10.1101/2024.11.04.621824 — bioinformatics — Posted on 2024-11-06
4053 TomoPicker: Annotation-Efficient Particle Picking in cryo-electron Tomograms
Uddin, M. R.; Ahmed, A. Y.; Tahmid, M. T.; Ul Alam, M. Z.; Freyberg, Z.; Xu, M.
10.1101/2024.11.04.620735 — bioinformatics — Posted on 2024-11-06
4055 Rthoptera: standardized insect bioacoustics in R
Rivas, F.; Buzzetti, F. M.; Brizio, C.; Pijanowski, B. C.
10.1101/2024.11.04.621915 — bioinformatics — Posted on 2024-11-06
4058 SingleFrag: A deep learning tool for MS/MS fragment and spectral prediction and metabolite annotation
Perez-Ribera, M.; Khan, M. F.; Gine, R.; Badia, J. M.; Junza, S.; Yanes, O.; Sales-Pardo, M.; Guimera, R.
10.1101/2024.11.04.621329 — bioinformatics — Posted on 2024-11-06
4059 Influence of metal ions on the isothermal self-assembly of DNA nanostructures
Rodriguez, A.; Barathraj, M.; Sarkar, K.; Nowzari, Z.; Mathivanan, J.; Talbot, H.; Morya, V.; Halvorsen, K.; Vangaveti, S.; Berglund, J. A.; Chandrasekaran, A. R.
10.1101/2024.11.04.621977 — bioengineering — Posted on 2024-11-06
4060 Platelet Membrane-Coated SPION for Targeted Paclitaxel Delivery and Magnetic Hyperthermia in Cancer Therapy
Tavakoli, M.; Maghsoudian, S.; Rezaei-Aderiani, A.; Hajiramezanali, M.; Amani, M.; Sharifikolouei, E.; Ghahremani, M. H.; Raoufi, M.; Motasadizadeh, H.; Dinarvand, R.
10.1101/2024.11.04.621819 — bioengineering — Posted on 2024-11-06
4061 Automated cell tracking using 3D nnUnet and Light Sheet Microscopy to quantify regional deformation in zebrafish
Teranikar, T. A.; Saeed, S.; LE, T. V.; Kang, Y.; Hernandez, G.; Nguyen, P.; Ding, Y.; Chuong, C.-J.; Lee, J. Y.; Ko, H.; Lee, J.
10.1101/2024.11.04.621759 — bioengineering — Posted on 2024-11-06
4063 Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads
Xue, D.; Xu, M.; Madden, M. D.; Lian, X.; Older, E. A.; Pulliam, C.; Hui, Y.; Shang, Z.; Gupta, G.; Raja, M. K.; Wang, Y.; Sardi, A.; Long, Y.; Chen, H.; Fan, D.; Bugni, T. S.; Testerman, T. L.; Wu, Q.; Li, J.
10.1101/2024.11.05.622009 — biochemistry — Posted on 2024-11-06
4064 A journey towards developing a new cleavable crosslinker reagent for in-cell crosslinking
Mueller, F.; Brutiu, B. R.; Saridakis, I.; Leischner, T.; Birklbauer, M. J.; Matzinger, M.; Madalinski, M.; Lendl, T.; Shaaban, S.; Dorfer, V.; Maulide, N.; Mechtler, K.
10.1101/2024.11.05.621843 — biochemistry — Posted on 2024-11-06
4066 Evolution and functioning of an X-A balance sex determination system in hops
Akagi, T.; Segawa, T.; Uchida, R.; Tanaka, H.; Shirasawa, K.; Yamagishi, N.; Yaegashi, H.; Natsume, S.; Takagi, H.; Abe, A.; Okuno, M.; Toyoda, A.; Sato, K.; Honniden, Y.; Zhang, C.; Ushijima, K.; Patzak, J.; Horakova, L.; Bacovsky, V.; Hobza, R.; Charlesworth, D.; Itoh, T.; Ono, E.
10.1101/2024.11.04.621975 — evolutionary biology — Posted on 2024-11-06
4067 Phylogeography of the electric rays of the family Narcinidae (Gill, 1862): systematic review and evidence of the dispersal routes to America.
Rodrigues-Filho, L. F. S.; Silva, R. K. C.; Lima, E. L.; Siccha-Ramirez, R.; Rincon, G.; Nunes, J. L. S.; Sampaio, I.; Sales, J. B. L.
10.1101/2024.11.04.621869 — evolutionary biology — Posted on 2024-11-06
4070 TOP-DOWN CLIMATIC PROCESSES MODULATE BIODIVERSITY-FUNCTIONING RELATIONSHIPS ACROSS NORTH AMERICAN FORESTS
Maluquer, X. S.; Godoy, O.; Benito, P. R.; Astigarraga, J.; Rodriguez-Sanchez, F.; Trivino, J. T.; Rueda, M.
10.1101/2024.11.04.621856 — ecology — Posted on 2024-11-06
4072 EEMtoolbox: A user-friendly R package for flexible ensemble ecosystem modeling
Pascal, L. V.; Vollert, S. A.; Bimler, M. D.; Baker, C. M.; Vernet, M.; Canessa, S.; Drovandi, C.; Adams, M. P.
10.1101/2024.11.03.621788 — ecology — Posted on 2024-11-06
4073 In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects
Rhon-Calderon, E. A.; Hemphill, C. N.; Savage, A. J.; Riesche, L.; Schultz, R. M.; Bartolomei, M. S.
10.1101/2024.11.06.622317 — developmental biology — Posted on 2024-11-06
4075 Comparative Analysis of Neural Crest Development in the Chick and Mouse
Kulesa, P. M.; Morrison, J. A. M.; pushel, i.; McKinney, M. C.; Gogol, M. M.; Scott, A. R.; Krumlauf, R.
10.1101/2024.11.06.622355 — developmental biology — Posted on 2024-11-06
4076 RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infection
Li, Y.; Gao, W.; Qiu, Y.; Pan, J.; Guo, Q.; Liu, X.; Geng, L.; Shen, Y.; Hu, Z.; Li, S.; Liu, S.; Yang, H.; Ge, B.; Fan, X.; Chen, X.; Li, J.
10.1101/2024.11.05.622030 — cell biology — Posted on 2024-11-06
4079 Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice
Chen, X. L.; Ojalill, M.; Jean, C.; Tancioni, I.; Jiang, S.; Boyer, A.; Ozmadenci, D.; Uryu, S.; Tarin, D.; Schlessinger, J.; Stupack, D. G.; Schlaepfer, D. D.
10.1101/2024.11.04.622008 — cell biology — Posted on 2024-11-06
4080 Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing
Motosugi, N.; Hasegawa, k.; Kurosaki, N.; Kawaguchi, E.; Izumi, K.; Iida, Y.; Higashiseto, M.; Yokoyama, K.; Sasaki, A.; Nakabayashi, K.; Fukuda, A.
10.1101/2024.11.04.622001 — cell biology — Posted on 2024-11-06
4081 The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells
Armento, A.; Sonntag, I.; Almansa Garcia, A.-C.; Sen, M.; Bolz, S.; Arango-Gonzalez, B.; Kilger, E.; Sharma, R.; Bharti, K.; Fernandez Godino, R.; de la Cerda, B.; Clark, S. J.; Ueffing, M.
10.1101/2024.11.06.622214 — cell biology — Posted on 2024-11-06
4084 The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation
Stacey, J. C. V.; Hrebik, D.; Nand, E.; Shetty, S. D.; Qu, K.; Boicu, M.; Anders-Osswein, M.; Dick, R. A.; Mothes, W.; Krausslich, H.-G.; Mueller, B.; Briggs, J. A. G.
10.1101/2024.11.06.622200 — microbiology — Posted on 2024-11-06
4087 Manipulation of alternative splicing of IKZF1 elicits distinct gene regulatory responses in T cells
Pastor, L.; Newman, J. R. B.; Callahan, C. M.; Pickin, R. R.; Atkinson, M. A.; Onengut-Gumuscu, S.; Concannon, P.
10.1101/2024.11.05.622018 — genomics — Posted on 2024-11-06
4089 Nucleosome repositioning in cardiac reprogramming
Harris, S.; Baksh, S.; Wang, X.; Anwar, I.; Pratt, R.; Dzau, V.; Hodgkinson, C.
10.1101/2024.11.05.622077 — genomics — Posted on 2024-11-06
4091 The MRAP2 accessory protein directly interacts with melanocortin-3 receptor to enhance signaling
Jamaluddin, A.; Wyatt, R. A.; Lee, J.; Dowsett, G.; Tadross, J. A.; Broichhagen, J.; Yeo, G. S. H.; Levitz, J.; Gorvin, C. M.
10.1101/2024.11.06.622243 — molecular biology — Posted on 2024-11-06
4092 Spinal cord phosphoproteome of a SCA2/ALS13 mouse model reveals alteration of ATXN2-N-term SH3-actin interactome and of autophagy via WNK1-MYO6-OPTN-SQSTM1
Almaguer-Mederos, L. E.; Reddy Kandi, A.; Sen, N.-E.; Canet-Pons, J.; Berger, L.-M.; Key, J.; Brunstein, M.-E.; Munch, C.; Gispert, S.; Auburger, G.
10.1101/2024.11.06.622233 — molecular biology — Posted on 2024-11-06
4093 Key gut microbiota components and functions in an aquatic keystone species across diets assessed by metaproteomics
Dumas, T.; Pible, O.; Grenga, L.; Esposti, D. D.; Delorme, N.; Geffard, O.; Chaumot, A.; Armengaud, J.
10.1101/2024.11.06.622251 — molecular biology — Posted on 2024-11-06
4095 Lack of functional polyester-biodegrading potential in marine versus terrestrial environments evidenced by an innovative airbrushing technique
Contreras-Moll, A.; Obrador-Viel, T.; Molina, R. D. I.; Aguilo-Ferretjans, M. d. M.; Nogales, B.; Bosch, R.; Christie-Oleza, J.
10.1101/2024.11.06.622231 — microbiology — Posted on 2024-11-06
4096 Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses
Banfield, J.; Valentin-Alvarado, L. E.; Shi, L.-D. E.; Robinson, C. M.; Bamert, R. S.; Coulibaly, F.; Barth, Z. K.; Aylward, F.; Schoelmerich, M. C.; Lei, S.; Sachdeva, R.; Knott, G. J.
10.1101/2024.11.05.622173 — microbiology — Posted on 2024-11-06
4100 Lrp1 facilitates infection of neurons by Jamestown Canyon virus
Frey, Z. D.; Price, D. A.; Connors, K. A.; Rush, R. E.; Brown, G.; Sterling, C. E.; Fatma, F.; Schwarz, M. M.; Ganaie, S.; Cui, X.; Wills, Z. P.; Leung, D. W.; Amarasinghe, G. K.; Hartman, A. L.
10.1101/2024.11.06.622176 — microbiology — Posted on 2024-11-06
4102 An Accessible 3D HepG2/C3A Liver Spheroid Model Supporting the Complete Intrahepatocytic Lifecycle of Plasmodium falciparum
Alqurashi, S. O.; Caygill, C. H.; Adolfi, A.; Carson, J.; Sturm, A.; Dechering, K. J.; Reimer, L.; Pennington, S. H.; Sharma, P.; Ward, S. A.; Biagini, G.
10.1101/2024.11.06.621813 — microbiology — Posted on 2024-11-06
4103 Antibacterial Compounds Against Non-Growing and Intracellular Bacteria
Kaldalu, N.; Berzins, N.; Fick, S. B.; Sharma, A.; Andersson, N. C.; Aedla, J.; Hinnu, M.; Puhar, A.; Hauryliuk, V.; Tenson, T.
10.1101/2024.11.06.622235 — microbiology — Posted on 2024-11-06
4104 Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines
Chen, W.; Tompkins, K. R.; Windsor, I. W.; Martinez, L. T.; Ramos, M.; Li, W.; Shrivastava, S.; Rajput, S.; Chang, J. S.; Sahasrabudhe, P.; Fennell, K. F.; McLellan, T. J.; West, G. M.; Dizon, K. P.; Yam, A.; Mitra, S.; Saha, S.; Sharaf, D.; McKeen, A. P.; Cadima, C. I.; Muik, A.; Swanson, W.; Moreno, R. M.; Daroca, P. M.; Sahin, U.; Anderson, A. S.; Wu, H.; Swanson, K. A.; Modjarrad, K.
10.1101/2024.11.04.621927 — immunology — Posted on 2024-11-06
4105 Nanoparticle-Supported, Rapid, Digital Quantification of Neutralizing Antibodies Against SARS-CoV-2 Variants
Mirjalili, S.; Ikbal, M. A.; Hou, C.-W.; Kalatehmohammdi, M.; Choi, Y.; KELBAUSKAS, L.; VanBlargan, L. A.; Hogude, B. G.; Murugan, V.; Diamond, M. S.; Wang, C.
10.1101/2024.11.05.622148 — immunology — Posted on 2024-11-06
4106 Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in experimental COVID-19
Rodrigues, P. B.; de Rezende Rodovalho, V.; Sencio, V.; Benech, N.; Creskey, M.; Silva Angulo, F.; Delval, L.; Robil, C.; Gosset, P.; Machelart, A.; Haas, J. T.; Descat, A.; Goossens, J. F.; BEURY, D.; Maurier, F.; Hot, D.; Wolowczuk, I.; Sokol, H.; Zhang, X.; Ramirez Vinolo, M. A.; Trottein, F.
10.1101/2024.11.05.622058 — immunology — Posted on 2024-11-06
4109 Mpox Vaccine Design Through Immunoinformatics and Computational Epitope Prediction
Rivera-Orellana, S.; Ramirez-Iglesias, J. R.; Acosta-Espana, J. D.; Espinosa-Espinosa, J.; Navarro, J.-C.; Herrera-Yela, A.; Lopez-Cortes, A.
10.1101/2024.11.05.622158 — bioinformatics — Posted on 2024-11-06
4111 Light-dependent flavin redox and adduct states control the conformation and DNA binding activity of the transcription factor EL222
Chaudhari, A. S.; Favier, A.; Tehrani, Z. A.; Koval, T.; Andersson, I.; Schneider, B.; Dohnalek, J.; Cerny, J.; Brutscher, B.; Fuertes, G.
10.1101/2024.11.06.618433 — biochemistry — Posted on 2024-11-06
4113 A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
Bacot, T.; Haberkorn, C.; Guilliet, J.; Cattel, J.; Kefi, M.; Nadalin, L.; Filee, J.; Boyer, F.; Gaude, T.; Laporte, F.; Tutagata, J.; Vontas, J.; Dusfour, I.; Bonneville, J.-M.; David, J.-P.
10.1101/2024.04.03.587871 — evolutionary biology — Posted on 2024-11-06
4114 CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization
Teixeira, V.; Singh, K.; Gama, J. B.; Celestino, R.; Xavier de Carvalho, A.; Pereira, P.; Abreu, C. M.; Dantas, T. J.; Carter, A. P.; Gassmann, R.
10.1101/2024.11.06.622207 — cell biology — Posted on 2024-11-06
4116 Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later.
Attaheri, A.; Ni Choisdealbha, A.; Rocha, S.; Brusini, P.; Di Liberto, G. M.; Mead, N.; Olawole-Scott, H.; Boutris, P.; Gibbon, S.; Williams, I.; Grey, C.; Alfaro e Oliveira, M.; Brough, C.; Flanagan, S.; Goswami, U.
10.1101/2022.11.02.514963 — neuroscience — Posted on 2024-11-06
4117 Phototropin connects blue light perception to starch metabolism in green algae
Yuan, Y.; Iannetta, A. A.; Kim, M.; Sadecki, P. W.; Arend, M.; Tsichla, A.; Ruiz-Sola, M. A.; Kepesidis, G.; Falconet, D.; Thevenon, E.; Tardif, M.; Brugiere, S.; Coute, Y.; Kleman, J.-P.; Sizova, I.; Schilling, M.; Jouhet, J.; Hegemann, P.; Li-Beisson, Y.; Nikoloski, Z.; Bastien, O.; Hicks, L. M.; Petroutsos, D.
10.1101/2024.02.12.579879 — plant biology — Posted on 2024-11-06
4118 A green lifetime biosensor for calcium that remains bright over its full dynamic range
van der Linden, F. H.; Thornquist, S. C.; ter Beek, R. M.; Huijts, J. Y.; Hink, M. A.; Gadella, T. W. J.; Maimon, G.; Goedhart, J.
10.1101/2024.11.05.622032 — cell biology — Posted on 2024-11-06
4119 Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase
Orofiamma, L. A.; Delos Santos, R. C.; Mehrabi, A.; Leshchyshyn, N.; Hesketh, G. G.; Rahmani, S.; Patel, A.; Fekri, F.; Ata, R.; Ratcliffe, C. D.; Crupi, M. J.; Mulligan, L.; Park, M.; Gingras, A.-C.; Antonescu, C. N.
10.1101/2024.11.05.622177 — cell biology — Posted on 2024-11-06
4122 A Proximity MAP of RAB GTPases
Gaudreault St-Laurent, V.; Marchand, B.; Larcher, R.; Nassari, S.; Bourassa, F.; Moreau, M.; Jean, D.; Boisvert, F.-M.; Brunet, M. A.; Jean, S.
10.1101/2024.11.05.621850 — cell biology — Posted on 2024-11-06
4125 Bidirectional control of neurovascular coupling by cortical somatostatin interneurons
Mohamed, B.; O Reilly, J.; Picaud, S.; Le Gac, B.; Belzic, E.; Castro, L. R.; Soula, H.; Dusart, I.; Li, D.; Cauli, B.
10.1101/2024.11.06.622247 — neuroscience — Posted on 2024-11-06
4126 Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study
Rowsthorn, E.; Cribb, L.; Sinclair, B.; Pham, W.; Chong, T.; Yiallourou, S.; Cavuoto, M.; Vivash, L.; O'Brien, T. J.; Shao, X.; Wang, D. J.; Law, M.; Pase, M. P.; Harding, I. H.
10.1101/2024.11.05.622194 — neuroscience — Posted on 2024-11-06
4129 Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion
Yang, X.; Yang, T.; Zhang, Z.; Zhang, Y.; Mei, X.; Gao, Y.; Wang, N.; Jiang, G.; Xu, Y.; Shen, Q.; Wei, Z.; Jousset, A.
10.1101/2024.11.04.621791 — ecology — Posted on 2024-11-06
4131 The phosphatase PP2C12 is a negative player in LRX-RALF-FER-mediated cell wall integrity sensing
Hou, X.; Bender, K. W.; Guerin, A.; Kadler, G.; Gupta, S.; Haefliger, M.; Diet, A.; Roffler, S.; Campanini, D.; Wicker, T.; Zipfel, C.; Ringli, C.
10.1101/2024.11.05.622083 — plant biology — Posted on 2024-11-06
4133 Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision
Seltzer, R.; Zer Eshel, G.; Yinon, O.; Hafani, A.; Eitan, O.; Matveev, S.; Levedev, G.; Davidovitz, M.; Ben Tov, T.; Sharabi, G.; Shapira, Y.; Shvil, N.; Atallah, I.; Hadad, S.; Ment, D.; Hadany, L.; Yovel, Y.
10.1101/2024.11.06.622209 — animal behavior and cognition — Posted on 2024-11-06
4134 Annotating CryoET Volumes: A Machine Learning Challenge
Peck, A.; Yu, Y.; Schwartz, J.; Cheng, A.; Ermel, U. H.; Kandel, S.; Kimanius, D.; Montabana, E.; Serwas, D.; Siems, H.; Wang, F.; Zhao, Z.; Zheng, S.; Haury, M.; Agard, D.; Potter, C.; Carragher, B.; Harrington, K.; Paraan, M.
10.1101/2024.11.04.621686 — cell biology — Posted on 2024-11-06
4136 R-Loop control and mitochondria genome stability requires the 5'-3' exonuclease/flap-endonuclease OEX1
Schatz-Daas, D.; Weber-Lotfi, F.; Le Blevenec, A.; Moratti, F.; Mercier, P.; Iqbal, R. K.; Bock, R.; Dietrich, A.; Gualberto, J. M.
10.1101/2024.11.05.621957 — plant biology — Posted on 2024-11-06
4137 DNA methylation is a key determinant of response to targeted and immune checkpoint therapies in metastatic renal cell carcinoma
Jeanneret, F.; Schoch, S.; Ballester, P.; Symeonides, S. N.; Laird, A.; Axelson, H.; Pflieger, D.; Battail, C.
10.1101/2024.11.05.622095 — bioinformatics — Posted on 2024-11-06
4140 Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy
Cao Le, A.; Cheong, D. K. Y.; Oudin, V.; Dick, J.; Alikhan, M.; Mandwie, M.; Alexander, I.; Kitching, A. R.; Gan, P.-Y.; Logan, G. J.; O'Sullivan, K. M.
10.1101/2024.09.09.612148 — immunology — Posted on 2024-11-06
4141 CD3, CD4, and CD8 staining, but not PD-L1, are positively correlated with overall survival in Asian breast cancer
Pan, J.-W.; Makmur, H.; Tai, J.-Y.; Ng, P.-S.; Leong, H. X. Y.; Hasan, S. N.; Yip, C.-H.; Rajadurai, P.; Teo, S.-H.
10.1101/2024.11.05.622035 — cancer biology — Posted on 2024-11-06
4142 Predicting Tumor Mutational Burden from UHF-Dielectrophoresis Crossover Frequency
Daverat, H.; Blasco, N.; Robert, S.; Pothier, A.; Rovini, A.; Boutaud, M.; Jemfer, C.; Dalmay, C.; Lalloue, F.; Durand, K.; Naves, T.
10.1101/2024.11.05.622085 — cancer biology — Posted on 2024-11-06
4145 Global Analysis by LC-MS/MS of N6-Methyladenosine and Inosine in mRNA Reveals Complex Incidence
Stejskal, S.; Rajecka, V.; Covelo-Molares, H.; Sinigaglia, K.; Brozinova, K.; Kasiarova, L.; Dohnalkova, M.; Reyes-Gutierrez, P. E.; Cahova, H.; Keegan, L. P.; O'Connell, M.; Vanacova, S.
10.1101/2024.11.04.621854 — molecular biology — Posted on 2024-11-06
4146 DNA Extraction Protocols for Animal Fecal Material on Blood Spot Cards
Llarena, A.-K.; Haverkamp, T. H. A.; Gulliksen, W. S.; Herstad, K.; Holst-Jensen, A.; Skjerve, E.; Rannem, L.; Rodriguez-Campos, S.; Oines, O.
10.1101/2024.11.03.621776 — microbiology — Posted on 2024-11-06
4147 Air-Liquid Interface Model for Influenza Aerosol Exposure In Vitro
Seibert, B.; Caceres, C. J.; Gay, L. C.; Shetty, N.; Faccin, F.; Carnaccini, S.; Walters, M.; Marr, L.; Lowen, A. C.; Rajao, D. S.; Perez, D. R.
10.1101/2024.11.04.621830 — microbiology — Posted on 2024-11-06
4148 Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice
Freytag, D.; Giorgiutti, S.; Wadier, N.; Depauw, S.; Hopsomer, G.; Mertz, P.; Auge, F.; Carapito, R.; Couillin, I.; Korganow, A.-S.; Pala, F.; Bosticardo, M.; Notarangelo, L.; rieux-laucat, f.; Riteau, N.; Kirstetter, P.; Soulas-Sprauel, P.
10.1101/2024.11.01.621470 — immunology — Posted on 2024-11-06
4149 A macrophage-smooth muscle cell axis influences vascular remodeling through activation of the EGFR pathway in giant cell arteritis
Chevalier, K.; Dionet, L.; Breillat, P.; Poux, M.; Dang, J.; Terris, B.; Bruneval, P.; Mouthon, L.; Lenoir, O.; Tharaux, P.-L.; Terrier, B.
10.1101/2024.10.31.621431 — immunology — Posted on 2024-11-06
4152 From Flowering Time to High Temperature Resilience: PHOTOPERIOD 1 (PPD-H1) Controls Spike Fertility through Improving Stress Resistance and Energy Metabolism under High Ambient Temperatures
Lan, T.; Walla, A.; Colpan Karsan, K. E.; Buchmann, G.; Wewer, V.; Metzger, S.; Haraldsson, E. B.; Helmsorig, G.; Thirulogachandar, V.; Simon, R.; von Korff, M.
10.1101/2024.11.04.621966 — plant biology — Posted on 2024-11-06
4156 Is Probiotic Supplementation During Pregnancy Safe for Healthy Populations? A Systematic Review of Preclinical Studies
COCA, M. R.; Perez-Fernandez, C.; Ruiz-Sobremazas, D.; Morales-Navas, M.; Colomina, T.; Lopez-Granero, C.; Sanchez-Santed, F.
10.1101/2024.11.04.621894 — developmental biology — Posted on 2024-11-06
4166 Marker gene fishing for single-cell data with complex heterogeneity
Shao, Y.; Gao, Q.; Wang, L.; Li, D.; Nixon, A.; Chan, C.; Li, Q.-J.; Xie, J.
10.1101/2024.11.03.621735 — bioinformatics — Posted on 2024-11-06
4168 Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies
Chernoff, C. S.; Belin-Rauscent, A.; Puaud, M.; Torrisi, S. A.; Fouyssac, M. S.; Nemeth, B.; Yu, C.; Higuera-Matas, A.; Jones, S.; Belin, D.
10.1101/2024.10.08.617254 — animal behavior and cognition — Posted on 2024-11-06
4169 Diverse ancestral representation improves genetic intolerance metrics
Han, A.; Sands, C. F.; Matelska, D.; Butts, J. C.; Ravanmehr, V.; Hu, F.; Villavicencio Gonzalez, E.; Katsanis, N.; Bustamante, C. D.; Wang, Q.; Petrovski, S.; Vitsios, D.; Dhindsa, R. S.
10.1101/2024.11.04.621955 — genetics — Posted on 2024-11-06
4172 One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation
Paillet, Y.; Zapponi, L.; Schall, P.; Monnet, J.-M.; Ammer, C.; Balducci, L.; Boch, S.; Brazaitis, G.; Campanaro, A.; Chianucci, F.; Doerfler, I.; Fischer, M.; Gosselin, M.; Gossner, M. M.; Heilmann-Clausen, J.; Hofmeister, J.; Hosek, J.; Jung, K.; Kepfer-Rojas, S.; Odor, P.; Tinya, F.; Trentanovi, G.; Vacchiano, G.; Vandekerkhove, K.; Weisser, W. W.; Wohlwend, M.; Burrascano, S.
10.1101/2024.02.12.579875 — ecology — Posted on 2024-11-06
4173 Evolutionarily recent transcription factors partake in human cell cycle regulation
Pulver, C.; Forey, R.; Lederer, A. R.; Begnis, M.; Rosspopoff, O.; Carlevaro, J.; Martins, F.; Planet, E.; Duc, J.; Raclot, C.; Offner, S.; Coudray, A.; Dorshel, A.; Trono, D.
10.1101/2024.11.04.621792 — cell biology — Posted on 2024-11-06
4177 Discovery of broad-spectrum bacterial polyamine detoxification inhibitors as potential antivirulence agents and antibiotic adjuvants
Moulding, P. B.; Flannagan, R. S.; Wong, J.; Soliman, A. M.; Elhenawy, W.; Heinrichs, D. E.; El-Halfawy, O. M.
10.1101/2024.10.18.618978 — microbiology — Posted on 2024-11-05
4180 Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities
Lane, L. E.; Doerfler, D. N.; LArgent, L. A.; Touchette, E.; Mills, B.; Bryant, J.; Roller, S. N.; Forsythe, E. S. S.
10.1101/2024.11.01.621607 — bioinformatics — Posted on 2024-11-05
4183 Analyses of transposable elements in arbuscular mycorrhizal fungi support evolutionary parallels with filamentous plant pathogens
Oliveira, J. I.; Lane, C.; Mugambi, K.; Yildirir, G.; Nicol, A. M.; Kokkoris, V.; Banchini, C.; Dadej, K.; Dettman, J.; Stefani, F.; Corradi, N.
10.1101/2024.11.04.621924 — genomics — Posted on 2024-11-05
4184 BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III
Chen, B.; Stark, D. C.; Jadhav, P. V.; Lynn-Nguyen, T. M.; Halligan, B. S.; Rossiter, N. J.; Sindoni, N.; Shin, M.; Paulo, J. A.; Chang, M.; Koo, I.; Koshkin, S.; Eyunni, S.; Ronchi, P.; Paulsen, M. T.; Morlacchi, P.; Hanna, D. A.; Lin, J.; Guerra, R. M.; Pagliarini, D.; Banerjee, R.; Parolia, A.; Ljungman, M.; Patterson, A. D.; Mancias, J. D.; Mosalaganti, S.; Sexton, J.; Cali, T.; Lyssiotis, C. A.; Shah, Y. M.
10.1101/2024.02.02.578646 — cell biology — Posted on 2024-11-05
4189 DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale
Firsanov, D.; Zacher, M.; Tian, X.; Zhao, Y.; Sformo, T. L.; Tombline, G.; Biashad, S. A.; Gilman, A.; Hamilton, N.; Patel, A.; Straight, M.; Lee, M.; Lu, J. Y.; Haseljic, E.; Williams, A.; Miller, N.; Zheng, Z.; Perelli, L.; Gurreri, E.; Zhang, L.; Guo, J.; Korotkov, A.; Volobaev, V.; Zhang, Z.; Heid, J.; Maslov, A.; Sun, S.; Wu, Z.; Gigas, J.; Hillpot, E.; Martinez, J.; Ablaeva, J.; Tam, L. M.; Couderc, C.; Hoopman, M.; Fujii, S.; Hayman, D. J.; Liu, H.; Cai, Y.; Leung, A. K. L.; Moritz, R.; Simons, M. J. P.; Nelson, C. B.; Abbeglen, L. M.; Schiffman, J. D.; Modesti, M.; Zhang, Z.; Gladyshev
10.1101/2023.05.07.539748 — cancer biology — Posted on 2024-11-05
4191 YAP controls cell migration and invasion through a Rho-GTPase switch
Shah, S. R.; Ren, C.; Tippens, N. D.; Park, J.; Mohyeldin, A.; Wang, S.; Vela, G.; Martinez-Gutierrez, J. C.; Margolis, S. S.; Schmidt, S.; Xia, S.; Quinones-Hinojosa, A.; Levchenko, A.
10.1101/602052 — cancer biology — Posted on 2024-11-05
4192 moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides
Zhu, C.; Liu, L. Y.; Ha, A.; Yamaguchi, T. N.; Zhu, H.; Hugh-White, R.; Livingstone, J.; Patel, Y.; Kislinger, T.; Boutros, P. C.
10.1101/2024.03.28.587261 — bioinformatics — Posted on 2024-11-05
4193 Joint representation and visualization of derailed cell states with Decipher
Nazaret, A.; Fan, J. L.; Lavallee, V.-P.; Burdziak, C.; Cornish, A. E.; Kiseliovas, V.; Bowman, R. L.; Masilionis, I.; Chun, J.; Eisman, S. E.; Wang, J.; Hong, J.; Shi, L.; Levine, R. L.; Mazutis, L.; Blei, D.; Pe'er, D.; Azizi, E.
10.1101/2023.11.11.566719 — bioinformatics — Posted on 2024-11-05
4197 Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
Tomlinson, P. R.; Knox, R.; Perisic, O.; Su, H.; Brierley, G. V.; Williams, R. L.; Semple, R. K.
10.1101/2023.11.02.565250 — biochemistry — Posted on 2024-11-05
4202 Transcriptomic data reveal divergent paths of chitinase evolution underlying dietary convergence in anteaters and pangolins
Allio, R.; Teullet, S.; Lutgen, D.; Magdeleine, A.; Koual, R.; Tilak, M.-K.; de Thoisy, B.; Emerling, C. A.; Lefebure, T.; Delsuc, F.
10.1101/2022.11.29.518312 — evolutionary biology — Posted on 2024-11-05
4204 Tree diversity increases carbon stocks and fluxes above- but not belowground in a tropical forest experiment
Schnabel, F.; Guillemot, J.; Barry, K. E.; Brunn, M.; Cesarz, S.; Eisenhauer, N.; Gebauer, T.; Guerrero-Ramirez, N. R.; Handa, I. T.; Madsen, C.; Mancilla, L.; Monteza, J.; Moore, T.; Oelmann, Y.; Scherer-Lorenzen, M.; Schwendenmann, L.; Wagner, A.; Wirth, C.; Potvin, C.
10.1101/2024.06.20.599915 — ecology — Posted on 2024-11-05
4205 A novel CCDC112-dependent process of sperm midpiece formation and epididymal maturation
O'Bryan, M. K.; Graffeo, M.; Nguyen, J.; Parast, F. Y.; Merriner, D. J.; Dunleavy, J.; Korneev, D.; Okuda, H.; O'Connor, A. E.; Conrad, D. F.; Nosrati, R.; Houston, B. J.
10.1101/2024.11.05.622046 — developmental biology — Posted on 2024-11-05
4208 Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling.
Giamundo, G.; Intartaglia, D.; Del Prete, E.; Polishchuk, E.; Andreone, F.; Ognibene, M.; Buonocore, S.; Hay Mele, B.; Salierno, F. G.; Monfregola, J.; Antonini, D.; Grumati, P.; Eva, A.; De Cegli, R.; Conte, I.
10.1101/2024.05.03.592332 — cell biology — Posted on 2024-11-05
4211 A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID-19-Flu Mucosal Vaccines
Zhu, J.; Sha, J.; Batra, H.; Jain, S.; Wu, X.; Hendrix, E.; Kilgore, P. B.; Sun, K.; Plante, K. S.; Plante, J. A.; Walker, J.; Tao, P.; Chopra, A. K.; Rao, V. B.
10.1101/2024.10.09.617418 — microbiology — Posted on 2024-11-05
4212 Interaction between climatic variation and pathogen diversity shape endemic disease dynamics in the agricultural settings
Bhandari, R.; Kaur, A.; Russell, I.; Romanus, O. M.; Brokaw, D.; Keinath, A. P.; Snipes, Z.; Rollins, P.; Baugher, N.; Meadows, I.; Torrance, T. N.; Dutta, B.; Sikora, E.; Molinari, R.; Soubeyrand, S.; Potnis, N.
10.1101/2024.09.27.615185 — microbiology — Posted on 2024-11-05
4213 The C3-C3aR axis modulates trained immunity in alveolar macrophages
Earhart, A. P.; Alburquerque, R. A.; Starick, M.; Nallapu, A.; Garnica, L.; Ozanturk, A. N.; Maurya, R. K.; Wu, X.; Haspel, J. A.; Kulkarni, H. S.
10.1101/2024.11.01.621042 — immunology — Posted on 2024-11-05
4216 Sufficiency of ITD for (biased) human auditory azimuthal perception
Azevedo, A. C. P. F. O. d.; Pellegrino, T. G.; Pena, J. L.; Marin, B.; Pavao, R.
10.1101/2024.11.05.622135 — neuroscience — Posted on 2024-11-05
4217 In vivo cell-type and brain region classification via multimodal contrastive learning
Yu, H.; Lyu, H.; Xu, E. Y.; Windolf, C.; Lee, E. K.; Yang, F.; Shelton, A. M.; Olsen, S.; Minavi, S.; Winter, O.; The International Brain Laboratory, ; Dyer, E. L.; Chandrasekaran, C.; Steinmetz, N. A.; Paninski, L.; Hurwitz, C.
10.1101/2024.11.05.622159 — neuroscience — Posted on 2024-11-05
4219 Presaccadic attentional shifts are not modulated by saccade amplitude
Zimmermann Bortoluzzi, L.; Carlos-Lima, E.; Mueller de Melo, G.; Hongjin Song Zhu, M.; Rohenkohl, G.
10.1101/2024.11.05.622100 — neuroscience — Posted on 2024-11-05
4221 Inhibition of β-catenin signaling by Amyloid-β in endothelial cells impairs vascular barrier integrity
Leasure, J. W.; Mai, T.; Fogel, A.; Danos, P.; Wang, L.; Sanborn, M. A.; Ye, Z.; Kim, Y.-M.; Wang, X.; Flores, J.; Mushtaq, M.; Toth, P. T.; Ong, S.-G.; Lazarov, O.; Rehman, J.
10.1101/2024.11.05.622172 — neuroscience — Posted on 2024-11-05
4224 Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex
Sokpor, G.; Ulmke, P. A.; Nguyen, H. D.; Pham, L.; Kakani, P.; Chu, V. T.; Arnold, S. J.; Brand-Saberi, B.; Nguyen, H. P.; Tuoc, T.
10.1101/2024.11.05.621758 — neuroscience — Posted on 2024-11-05
4225 DNA replication fork speed Acts as an Engine in Cortical Neurogenesis
Wang, J.; Kong, Y.; Li, X.; Tan, Y.; Xiang, K.; Juan Carlos, B. L.; Shi, L.
10.1101/2024.11.05.622174 — neuroscience — Posted on 2024-11-05
4226 Selective Enhancement of the Interneuron Network and Gamma-Band Power via GluN2C/GluN2D NMDA Receptor Potentiation
Camp, C. R.; Banke, T. G.; Xing, H.; Yu, K.; Perszyk, R. E.; Epplin, M.; Akins, N.; Zhang, J.; Benke, T. A.; Yuan, H.; Liotta, D.; Traynelis, S. F.
10.1101/2024.11.05.622179 — neuroscience — Posted on 2024-11-05
4227 Mitochondrial dysfunction Impairs the Nuclear Pore Complex in Parkinson's Disease Pathogenesis
Riaz, Z.; Chang, Y.-T.; Zenitsky, G.; Jin, H.; Anantharam, V.; Kanthasamy, A.; Kanthasamy, A.
10.1101/2024.11.05.622143 — neuroscience — Posted on 2024-11-05
4229 Flexible 3D kirigami probes for in vitro and in vivo neural applications
Jung, M.; Abu Shihada, J.; Decke, S.; Koschinski, L.; Graff, P. S.; Pazmino, S. M.; Hoellig, A.; Koch, H.; Musall, S.; Offenhaeusser, A.; Montes, V. R.
10.1101/2024.11.05.622167 — neuroscience — Posted on 2024-11-05
4230 Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain
Gonzalez-Padilla, D.; Eagles, N. J.; Cano, M.; Pertea, G.; Jaffe, A. E.; Maynard, K. R.; Hancock, D. B.; Handa, J. T.; Martinowich, K.; Collado-Torres, L.
10.1101/2024.11.05.622149 — neuroscience — Posted on 2024-11-05
4232 Microglia modulate cerebral blood flow and neurovascular coupling through ectonucleotidase CD39
Fu, Z.; Ganesana, M.; Hwang, P.; Tan, X.; Kinkaid, M. M.; Sun, Y.-Y.; Bian, E.; Weybright, A.; Sol-Church, K.; Eyo, U.; Pridans, C.; Quintana, F. J.; Robson, S. C.; Kumar, P.; Venton, B. J.; Schaefer, A.; Kuan, C.-Y.
10.1101/2024.11.05.622122 — neuroscience — Posted on 2024-11-05
4235 Food intake enhances hippocampal sharp wave-ripples
Kaya, E.; Wegienka, E.; Akhtarzandi-Das, A.; Do, H.; Eban-Rothschild, A.; Rothschild, G.
10.1101/2024.10.08.617304 — neuroscience — Posted on 2024-11-05
4238 Epidermal Collagen Actively Regulates the Aging of Sensory Neurons
Krishna, M.; Waghmare, S. G.; Franitza, A. L.; Maccoux, E. C.; E, L.
10.1101/2024.05.07.593041 — neuroscience — Posted on 2024-11-05
4240 Comparative spatiotemporal single cell transcriptomes reveal rewiring of pre-existing regulations during emergence of Kranz anatomy in C4 grasses
Zhao, C.; Yang, J.; Ni, A.-T.; Chen, H.; Su, H.; Cheng, Y.-T.; Li, X.; Zhong, L.; Fang, D.; Sun, H.-R.; Yi, J.; Wang, Y.; Wang, Y.; Lyu, M.-J. A.; Ni, X.; Chen, L.; Li, H.; Yu, G.; Wang, Y.; Chen, R.; Yu, H.; Shao, W.; Sun, H.; Bai, Y.; Li, C.; Dong, Y.; Zou, C.; Tu, X.; Ma, S.; Guo, X.; Zhang, G.; Wang, P.; Liu, H.; Wei, T.; Gu, Y.; Xu, X.; Zhu, X.-G.
10.1101/2024.10.28.620769 — plant biology — Posted on 2024-11-05
4241 Zebrafish as a model to study PERK function in developmental diseases: implications for Wolcott-Rallison syndrome
Almeida, L. M.; Lima, L. P.; Oliveira, N. A. S.; Silva, R. F. O.; Sousa, B.; Bessa, J.; Pinho, B. R.; Oliveira, J. M. A.
10.1101/2024.04.16.589737 — pharmacology and toxicology — Posted on 2024-11-05
4243 Harnessing Smartphone RGB Imagery and LiDAR Point Cloud for Enhanced Leaf Nitrogen and Shoot Biomass Assessment - Chinese Spinach as a Case Study
Harikumar, A.; Shenhar, I.; R.Pebes-Trujillo, M.; Qin, L.; Moshelion, M.; Jie, H.; Ng, K. W.; Gavish, M.; Herrmann, I.
10.1101/2024.10.26.620395 — bioinformatics — Posted on 2024-11-05
4245 Climate and predation drive variation of diel activity patterns in chacma baboons (Papio ursinus) across southern Africa
Dzingwena, L.; Thel, L.; Choisy, M.; Garbett, R.; Wilkinson, A.; Venter, J.; Fritz, H.; Huchard, E.; Prugnolle, F.; Rougeron, V.
10.1101/2024.11.05.622068 — animal behavior and cognition — Posted on 2024-11-05
4247 Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition
Lozovska, A.; Casaca, A.; Novoa, A.; Kuo, Y.-Y.; Jurberg, A. D.; Martins, G. G.; Hadjantonakis, A.-K.; Mallo, M.
10.1101/2023.08.22.554351 — developmental biology — Posted on 2024-11-05
4249 Differential Ubiquitination of Host Proteins in Response to IPNV and ISAV viruses in Atlantic salmon
Stewart, R.; Guitian, X. S.; Gervais, O.; Jin, Y.; Salisbury, S.; Martin, S. A. M.; Ballantyne, M.; Orosa-Puente, B.; Robledo, D.
10.1101/2024.11.05.622028 — molecular biology — Posted on 2024-11-05
4250 Hydrophobins from Aspergillus mediate fungal interactions with microplastics
Klauer, R. R.; Silvestri, R.; White, H.; Hayes, R. D.; Riley, R.; Lipzen, A.; Barry, K. W.; Grigoriev, I. V.; Talag, J.; Bunting, V.; Stevenson, Z.; Solomon, K. V.; Blenner, M.
10.1101/2024.11.05.622132 — molecular biology — Posted on 2024-11-05
4252 A model, mixed-species urinary catheter biofilm derived from spinal cord injury patients
Noorian, P.; Hamann, K.; Hoque, M. M.; Espinoza-Vergara, G.; To, J.; Leo, D.; Chari, P.; Weber, G.; Marial, O.; Pryor, J.; Duggin, I. G.; Lee, B. B.; Rice, S.; McDougald, D.
10.1101/2024.11.04.621968 — microbiology — Posted on 2024-11-05
4259 Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
Zacharia, N. K.; Kuhns, S.; Boegholm, N.; Christensen, A.; Wang, J.; Petriman, N. A.; Lorentzen, A.; Fialova, J. L.; Menguy, L.; Saunier, S.; Christensen, S. T.; Andersen, J. S.; Bhogaraju, S.; lorentzen, e.
10.1101/2024.11.05.620812 — biochemistry — Posted on 2024-11-05
4260 Improved split prime editors enable efficient in vivo genome editing
Wei, R.; Yu, Z.; Ding, L.; Lu, Z.; Yao, K.; Zhang, H.; Huang, B.; He, M.; Ma, L.
10.1101/2024.11.05.622013 — genomics — Posted on 2024-11-05
4264 Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi
Li, X.; Tian, L.; Xu, Y.; Tan, J.; Li, J.; ONeil, N.; Hirst, M.; Hieter, P.; Zhang, Y.
10.1101/2024.11.05.622059 — microbiology — Posted on 2024-11-05
4265 Ecological Determinants of Altruism in Prokaryote Antivirus Defense
Biba, D. A.; Makarova, K. S.; Wolf, Y. I.; Waldron, L. D.; Koonin, E. V.; Rochman, N. D.
10.1101/2024.11.05.622165 — microbiology — Posted on 2024-11-05
4266 Chronic mycobacteria infection triggers macrophage senescence
Scarpa, E.; Oliveri, D.; Moschetti, G.; Vianello, A.; Griego, A.; Rondelli, D.; Antinori, B.; Marchello, G.; Santarelli, P.; Albanese, M.; Cidonio, G.; Manganaro, L.; Lore, N. I.; Rizzello, L.
10.1101/2024.11.05.622137 — microbiology — Posted on 2024-11-05
4267 Pseudomonas aeruginosa essential gene perturbations that confer vulnerability to the mammalian host environment
Prasad, N. K.; Ward, R. D.; Yu, M. A.; Kwon, M. S.; Banta, A. B.; Rosenberg, O. S.; Peters, J. M.
10.1101/2024.11.05.622029 — microbiology — Posted on 2024-11-05
4270 PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing
Lee, M. H.; Perez-Lopez, A.; Knodler, L.; Nguyen, G.; Walker, G. T.; Behnsen, J.; Silva, S.; Celli, J.; Tamin, M. A.; Liang, M. H.; Melchior, K.; Argueta, F. A.; Nuccio, S.-P.; Raffatellu, M.
10.1101/2024.11.05.622138 — microbiology — Posted on 2024-11-05
4272 Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly
Dutta, M.; Dolan, K. A.; Amiar, S.; Bass, E. J.; Sultana, R.; Voth, G. A.; Stahelin, R. V.; Brohawn, S. G.
10.1101/2024.11.04.620124 — microbiology — Posted on 2024-11-05
4274 Automatic surveillance of Escherichia coli bacteriological strains within clinical settings
Rodriguez Palomo, R.; Guerrero-Lopez, A.; Sevilla-Salcedo, C.; Rodriguez-Temporal, D.; Rodriguez-Sanchez, B.; Gomez-Verdejo, V.
10.1101/2024.11.05.622049 — microbiology — Posted on 2024-11-05
4276 Natural variation of the streptococcal Group A carbohydrate biosynthesis genes impacts host-pathogen interaction
Tamminga, S. M.; Schipper, K.; Murner, N.; Davies, M. A.; Berkhout, P.; Bessen, D. E.; Korotkova, N.; Pannekoek, Y.; van Sorge, N. M.
10.1101/2024.11.04.621835 — microbiology — Posted on 2024-11-05
4277 Neutralizing antibody evasion of SARS-CoV-2 JN.1 derivatives KP.3, KP.3.1.1, LB.1, and XEC
Sano, K.; Miyakawa, K.; Kato, H.; Kimura, Y.; Goto, A.; Ryo, A.; Watanabe, S.; Hasegawa, H.
10.1101/2024.11.04.621772 — immunology — Posted on 2024-11-05
4278 DNA-SaM, a robust system for large-scale data storage
Huang, X.; Wang, Y.; Xu, J.; Nie, Z.; Huang, J.; Wu, Y.; Qin, Z.; Dai, J.; Wang, Y.
10.1101/2024.11.04.621825 — synthetic biology — Posted on 2024-11-05
4280 Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein
Cuypers, M.-L.; Jaspers, T.; Clerckx, J.; Leekens, S.; Cawthorne, C.; Bormans, G.; Cleeren, F.; Geukens, N.; De Strooper, B.; Dewilde, M.
10.1101/2024.11.04.621218 — pharmacology and toxicology — Posted on 2024-11-05
4281 Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance
Muzata, D.; Sanyal, D.; A, S.; Pandey, D.; Chakraborti, S.; Chivukula, A. S.; Jasuja, R.; Uversky, V. N.; Zielinski, D. C.; Upadhyay, P. D.; Albers, M. W.; Chowdhury, S.
10.1101/2024.10.31.621387 — biophysics — Posted on 2024-11-05
4282 Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny
Hunt, M.; Hinrichs, A. S.; Anderson, D.; Karim, L.; Dearlove, B. L.; Knaggs, J.; Constantinides, B.; Fowler, P. W.; Rodger, G.; Street, T. L.; Lumley, S. F.; Webster, H.; Sanderson, T.; Ruis, C.; Kotzen, B.; De Maio, N.; Amenga-Etego, L. N.; Amuzu, D. S.; Avaro, M.; Awandare, G. A.; Ayivor-Djanie, R.; Barkham, T.; Bashton, M.; Batty, E. M.; Bediako, Y.; De Belder, D.; Benedetti, E.; Bergthaler, A.; Boers, S. A.; Campos, J.; Carr, R. A. A.; Chen, Y. Y. C.; Cuba, F.; Dattero, M. E.; Dejnirattisai, W.; Dilthey, A. T.; Duedu, K. O.; Endler, L.; Engelmann, I.; Francisco, N. M.; Fuchs, J.; Gnimpieba
10.1101/2024.04.29.591666 — bioinformatics — Posted on 2024-11-05
4284 Computational and in vitro evaluation of probiotic treatments for nasal Staphylococcus aureus decolonization
Tepekule, B.; Barcik, W.; Staiger, W. I.; Bergada-Pijuan, J.; Scheier, T.; Brülisauer, L.; Hall, A. R.; Günthard, H. F.; Hilty, M.; Kouyos, R. D.; Brugger, S. D.
10.1101/2022.08.28.505587 — microbiology — Posted on 2024-11-05
4285 Decoding Visual Spatial Attention Control
Meyyappan, S.; Rajan, A.; Yang, Q.; Mangun, G. R.; Ding, M.
10.1101/2023.08.05.552084 — neuroscience — Posted on 2024-11-05
4286 Open-source Tools for CryoET Particle Picking Machine Learning Competitions
Harrington, K. I.; Zhao, Z.; Schwartz, J.; Kandel, S.; Ermel, U.; Paraan, M.; Potter, C.; Carragher, B.
10.1101/2024.11.04.621608 — bioinformatics — Posted on 2024-11-05
4287 Structure of the microtubule anchoring factor NEDD1 bound to the γ-tubulin ring complex
Munoz Hernandez, H.; Xu, Y.; Zhang, D.; Xue, A.; Aher, A.; Pellicer Camardiel, A.; Walker, E.; Maxer, F.; Kapoor, T. M.; Wieczorek, M.
10.1101/2024.11.05.622067 — biochemistry — Posted on 2024-11-05
4288 Multiple roles for TFG ring complexes in neuronal cargo trafficking
Zhang, Z.; Lettman, M. M.; Schuh, A.; Bhattacharyya, B.; Randolph, P. S.; Nandakumar, T.; Kulkarni, I.; Roach, A.; Alvin, J.; Gengler, D.; Stagg, S.; Keck, J.; Audhya, A.
10.1101/2024.11.05.621662 — biochemistry — Posted on 2024-11-05
4289 Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol
Zhou, X.; van der Stoel, M. M.; Kaptan, S.; Li, H.; Li, S.; Holtta, M.; Vihinen, H.; Jokitalo, E.; Thiele, C.; Pietilainen, O.; Morioka, S.; Sasaki, J.; Sasaki, T.; Vattulainen, I.; Ikonen, E.
10.1101/2024.11.04.621832 — cell biology — Posted on 2024-11-05
4291 Potassium ferric oxalate nanoparticles prevent human blood clotting and thrombosis in a mouse model
Yenurkar, D.; Choudhary, A.; Shrivastava, A.; Pragya, P.; Mandal, S.; Soni, P.; Pradhan, L.; Singh, A.; Sarkar, A.; Mukherjee, S.
10.1101/2024.11.04.621820 — pathology — Posted on 2024-11-05
4292 A rare HSC-derived megakaryocyte progenitor accumulates via enhanced survival and contributes to exacerbated thrombopoiesis upon aging
Manso, B. A.; Medina, P.; Smith-Berdan, S.; Rodriguez y Baena, A.; Bachinsky, E.; Mok, L.; Deguzman, A.; Avila, S. B.; Chattopadhyaya, S.; Rommel, M. G. E.; Jonsson, V. D.; Forsberg, C.
10.1101/2024.11.04.621964 — cell biology — Posted on 2024-11-05
4294 KLF7-Regulated ITGA2 as a Therapeutic Target for Inhibiting Oral Cancer Stem Cells
QI, X.; Zhou, J.; Wang, P.; Li, Y.; Li, H.; Miao, Y.; Ma, X.; Luo, X.; He, Y.; Zhang, Z.; Shen, W.; Zhao, W.; Cui, R.; Li, C.; Zhu, H.; Lyu, J.
10.1101/2024.11.04.621805 — cancer biology — Posted on 2024-11-05
4296 De novo detection of somatic variants in high-quality long-read single-cell RNA sequencing data
Dondi, A.; Borgsmüller, N.; Ferreira, P. F.; Haas, B. J.; Jacob, F.; Heinzelmann-Schwarz, V.; Tumor Profiler Consortium, ; Beerenwinkel, N.
10.1101/2024.03.06.583775 — cancer biology — Posted on 2024-11-05
4298 Tomato roots exhibit distinct, development-specific responses to bacterial-derived peptides
Leuschen-Kohl, R. L.; Roberts, R.; Stevens, D. M.; Zhang, N.; Buchanan, S.; Pilkey, B.; Coaker, G.; Iyer-Pascuzzi, A. S.
10.1101/2024.11.04.621969 — plant biology — Posted on 2024-11-05
4299 PATROL1-mediated H+-ATPase translocation boosts plant growth under drought by optimizing root and leaf functions
Katsuhama, N.; Sakoda, K.; Kimura, H.; Shimizu, Y.; Sakai, Y.; Nagata, K.; Abe, M.; Terashima, I.; Yamori, W.
10.1101/2024.11.04.621996 — plant biology — Posted on 2024-11-05
4300 RNA adapts its flexibility to efficiently fold and resist unfolding
Jang, S. S.; Ray, K. K.; Lynall, D. G.; Shepard, K. L.; Nuckolls, C.; Gonzalez, R. L.
10.1101/2024.05.27.595525 — biophysics — Posted on 2024-11-05
4304 Encoding of cerebellar dentate neuronal activity during visual attention in rhesus macaques
Flierman, N. A.; Koay, S. A.; van Hoogstraten, W. S.; Ruigrok, T. J. H.; Roelfsema, P.; Badura, A.; De Zeeuw, C. I.
10.1101/2024.07.18.604119 — neuroscience — Posted on 2024-11-05
4310 SeedMatExplorer: The transcriptome atlas of Arabidopsis seed maturation
Artur, M. A. S.; Koetsier, R. A.; Willems, L. A. J.; Bakermans, L. L.; van Driel, A. D.; Dongus, J. A.; Dekkers, B. J. W.; Marques, A. C. S. S.; Sami, A. A.; Nijveen, H.; Bentsink, L.; Hilhorst, H.; Teixeira, R. N.
10.1101/2024.11.04.621888 — plant biology — Posted on 2024-11-05
4311 Analyses of transposable elements in arbuscular mycorrhizal fungi support evolutionary parallels with fungal plant pathogens
Oliveira, J. I.; Lane, C.; Mugambi, K.; Yildirir, G.; Nicol, A. M.; Kokkoris, V.; Banchini, C.; Dadej, K.; Dettman, J.; Stefani, F.; Corradi, N.
10.1101/2024.11.04.621924 — genomics — Posted on 2024-11-05
4312 Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies
Khamvongsa-Charbonnier, L.; Kremmer, L.; Torres, M.; Krifa, S.; Aubert, C.; Corbet, A.; Crespo, L.; Roder, L.; Perrin, L.; Arquier, N.
10.1101/2024.10.09.617032 — physiology — Posted on 2024-11-05
4316 Comprehensive Biosynthetic Analysis of Human Microbiome Reveals Diverse Protective Ribosomal Peptides
ZHANG, J.; ZHANG, D.; Xu, Y.; ZHANG, J.; Liu, R.; GAO, Y.; SHI, Y.; CAI, P.; ZHONG, Z.; HE, B.; LI, X.; Zhou, H.; Chen, M.; LI, Y.-x.
10.1101/2024.07.16.603675 — microbiology — Posted on 2024-11-05
4319 Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo
Ichimura, T.; Kakizuka, T.; Taniguchi, Y.; Ejima, S.; Sato, Y.; Itano, K.; Seiriki, K.; Hashimoto, H.; Sugawara, K.; Itoga, H.; Onami, S.; Nagai, T.
10.1101/2023.08.21.553997 — developmental biology — Posted on 2024-11-05
4322 In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer
Kumar, M.; Singh, S. B.; Vasyliv, I.; Habte, F. G.; Kalita, M.; Alam, I. S.; Dai, S.-Y.; James, M. L.; Rao, J.; Beziere, N.; Daldrup-Link, H. E.
10.1101/2024.09.28.615608 — immunology — Posted on 2024-11-05
4324 A consensus definition for deep layer 6 excitatory neurons in mouse neocortex
Kim, S.-J.; Babola, T. A.; Lee, K.; Matney, C. J.; Spiegel, A. C.; Liew, M. H.; Schulteis, E. M.; Coye, A. E.; Proskurin, M.; Kang, H.; Kim, J. A.; Chevee, M.; Lee, K.; Kanold, P. O.; Goff, L. A.; Kim, J.; Brown, S. P.
10.1101/2024.11.04.621933 — neuroscience — Posted on 2024-11-05
4325 Small molecule modulator of neuronal lysosome positioning and function resolves Alzheimers Disease-linked pathologies in cultured human neurons
Snead, A. M.; Patel, S.; Krout, M.; Hippman, R. S.; Smith, G.; Dileep, D.; Chagoor, N.; Shi, R.; Linares, R.; Dobria, A.; Cologna, S. M.; Crowder, C.; Aldrich, L. N.; Gowrishankar, S.
10.1101/2024.11.04.621986 — cell biology — Posted on 2024-11-05
4327 Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects
Zequeira, S.; Gazarov, E. A.; Güvenli, A. A.; Berthold, E. C.; Senetra, A. S.; Febo, M.; Hiranita, T.; McMahon, L. R.; Sharma, A.; McCurdy, C. R.; Setlow, B.; Bizon, J. L.
10.1101/2024.09.26.615028 — neuroscience — Posted on 2024-11-04
4331 Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replication
Owino, C. O.; Narmada, B. C.; Yi Lin, G.; Poh Kim Aw, P.; Ganesh, N.; Siying, J. T.; Plissonnier, M.-L.; Matan, T. T.; Shirgaonkar, N.; Bifani, J. P.; Levrero, M.; Periyasamy, G.; Lim, S. G.; DasGupta, R.
10.1101/2024.10.23.619969 — microbiology — Posted on 2024-11-04
4333 A high-resolution analysis of arrestin2 interactions responsible for CCR5 endocytosis
Petrovic, I.; Desai, S.; Isaikina, P.; Abiko, L. A.; Spang, A.; Grzesiek, S.
10.1101/2024.11.04.621860 — biochemistry — Posted on 2024-11-04
4334 Identification of Novel FosX Family Determinants from Diverse Environmental Samples
Kieffer, N.; Bohm, M.-E.; Berglund, F.; Marathe, N. P.; Gillings, M. P.; Larsson, D. G. J.
10.1101/2024.11.04.621841 — microbiology — Posted on 2024-11-04
4339 Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy
Gupta, S.; Martinov, T.; Thelen, A.; Sunahara, M.; Mureli, S.; Vazquez, A.; Gerdts, J.; Dandekar, R.; Cortese, I.; Fouassier, C.; Schanzer, E.; Urnov, F. D.; Marson, A.; Shy, B. R.; Greenberg, P. D.; Wilson, M. R.
10.1101/2024.11.04.621904 — neuroscience — Posted on 2024-11-04
4340 CausalXtract: a flexible pipeline to extract causal effects from live-cell time-lapse imaging data
Simon, F.; Comes, M. C.; Tocci, T.; Dupuis, L.; Cabeli, V.; Lagrange, N.; Mencattini, A.; Parrini, M. C.; Martinelli, E.; Isambert, H.
10.1101/2024.02.06.579177 — systems biology — Posted on 2024-11-04
4342 De novo identification of universal cell mechanics gene signatures
Urbanska, M.; Ge, Y.; Winzi, M.; Abuhattum, S.; Ali, S. S.; Herbig, M.; Kraeter, M.; Toepfner, N.; Durgan, J.; Florey, O.; Dori, M.; Calegari, F.; Lolo, F.-N.; del Pozo, M. A.; Taubenberger, A.; Cannistraci, C. V.; Guck, J.
10.1101/2021.04.26.441418 — biophysics — Posted on 2024-11-04
4343 The Cryo-EM structure of TRPC1 and TRPC5 heterotetramer
Chen, Y.; Che, T.; Cheng, X.; Yang, X.; Fu, Y.; Zhang, W.; Lv, S.; Yang, T.; Peng, Q.; Nan, W.; Wan, S.; Hua, Y.; Li, J.; Wu, X.; Hu, H.; Zhang, Y.; Liu, Y.; Yang, M.; Zeng, S.; Li, J.; Xiong, B.; Zhang, J.
10.1101/2024.11.03.621705 — biophysics — Posted on 2024-11-04
4345 Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies
Perez Almeria, C. V.; Otun, O.; Schlimgen, R.; Lamme, T. D.; Crudden, C. J.; Youssef, N.; Musli, L.; Jenjak, S.; Bobkov, V.; Drube, J.; Hoffmann, C.; Volkman, B.; Granier, S.; BECHARA, C.; Siderius, M.; Heukers, R.; Schafer, C. T.; Smit, M. J.
10.1101/2024.11.04.621790 — biochemistry — Posted on 2024-11-04
4346 Non-gonadal PIWI protein, Aubergine, regulates regenerative stem cell proliferation and tumourigenesis in the Drosophila adult intestine.
Bellec, K.; Carroll, L. R.; Pennel, K. A.; Tian, Y.; Yu, Y.; Cameron, A. R.; Herdia, F.; Gontijo, A. M.; Edwards, J.; Hayashi, R.; Cordero, J. B.
10.1101/2024.11.04.621896 — developmental biology — Posted on 2024-11-04
4348 Wnt5a and Notum Influence the Temporal Dynamics of Cartilaginous Mesenchymal Condensations in Developing Trachea.
Bottasso-Arias, N.; Mohanakrishnan, M.; Trovillion, S.; Burra, K.; Russell, N.; Wu, Y.; Xu, Y.; Sinner, D. I.
10.1101/2024.09.02.610014 — developmental biology — Posted on 2024-11-04
4349 Spatiotemporal transcriptomic niches of complement pathway and serine protease inhibitor activation in aging and infection
Kern, F.; Wagner, V.; Wahl, V.; Ludwig, N.; Graf, S.; Amand, J.; Foltz, A.; Atkins, M.; Kedir, B.; Hadjilaou, A.; Flotho, M.; Grandke, F.; Wartenberg, P.; Hollenhorst, M. I.; Lotter, H.; Mueller, R.; Boehm, U.; Hahn, O.; Jacobs, T.; Krasteva-Christ, G.; Wyss-Coray, T.; Keller, A.
10.1101/2024.11.04.621811 — molecular biology — Posted on 2024-11-04
4352 Microbes display broad diversity in cobamide preferences
Mok, K. C.; Sokolovskaya, O. M.; Deutschbauer, A. C.; Carlson, H. K.; Taga, M. E.
10.1101/2024.11.04.621602 — microbiology — Posted on 2024-11-04
4353 Antagonism as a foraging strategy in microbial communities
Stubbusch, A. K. M.; Peaudecerf, F. J.; Soo Lee, K.; Paoli, L.; Schwartzman, J.; Stocker, R.; Basler, M.; Schubert, O. T.; Ackermann, M.; Magnabosco, C.; D'Souza, G. G.
10.1101/2024.11.04.621785 — microbiology — Posted on 2024-11-04
4354 Identification of novel thiazole derivatives as flaviviral protease inhibitors against DENV and JEV
Murtuja, S.; Das, S.; Jana, I. D.; Shilkar, D.; Rakshit, G.; Sarkar, B.; Sinha, B. N.; Dewangan, R. P.; Mondal, A.; Jayaprakash, V.
10.1101/2024.11.04.621919 — microbiology — Posted on 2024-11-04
4356 Chromatin mimicry by human JC virus
Schaefer, U.; Miroshnikova, Y. A.; Xie, W.; Larson, A. G.; Lu, Z.; Chen, S.; Bradic, M.; Goldgur, Y.; Chen, K.; Sharma, V. P.; Cao, J.; Patel, D. J.; Narlikar, G. J.; Wickstrom, S. A.; Tarakhovsky, A.
10.1101/2024.11.04.621823 — microbiology — Posted on 2024-11-04
4357 Type IV pili-associated secretion of a biofilm matrix protein from Clostridium perfringens that forms intermolecular isopeptide bonds
Kivimaki, S. E.; Dempsey, S.; Tani, J. M.; Camper, C.; Hicklin, I. K.; Blaby-Haas, C. E.; Brown, A. M.; Melville, S.
10.1101/2024.11.04.621531 — microbiology — Posted on 2024-11-04
4358 Weberviruses are gut-associated phages that infect Klebsiella spp.
Dawson, S. J.; Shibu, P.; Garnett, S.; Newberry, F.; Brook, T. C.; Tijani, T.; Kujawska, M.; Hall, L. J.; McCartney, A. L.; Negus, D.; Hoyles, L.
10.1101/2024.11.04.620279 — microbiology — Posted on 2024-11-04
4359 Large-scale investigation for antimicrobial activity reveals novel defensive species across the healthy skin microbiome
Nguyen, U. T.; Salamzade, R.; Sandstrom, S.; Swaney, M. H.; Townsend, E. C.; Wu, S.; Cheong, J. Z. A.; Sardina, J. A.; Ludwikoski, I.; Rybolt, M.; Wan, H.; Carlson, C. M.; Zaronowaki, R.; Andes, D. R.; Currie, C.; Kalan, L.
10.1101/2024.11.04.621544 — microbiology — Posted on 2024-11-04
4361 PreciCE: Precision engineering of cell fates via data-driven multi-gene control of transcriptional networks
Magnusson, J. P.; Roohani, Y.; Stauber, D.; Situ, Y.; Teba, P. R. d. C.; Sandberg, R.; Leskovec, J.; Qi, L. S.
10.1101/2024.11.04.621938 — synthetic biology — Posted on 2024-11-04
4362 Using phage display for rational engineering of a higher affinity humanized 3-phosphohistidine-specific antibody
Martyn, G. D.; Kalagiri, R.; Veggiani, G.; Stanfield, R. L.; Choudhuri, I.; Sala, M.; Meisenhelder, J.; Chen, C.; Biswas, A.; Levy, R. M.; Lyumkis, D.; Wilson, I. A.; Hunter, T.; Sidhu, S. S.
10.1101/2024.11.04.621849 — synthetic biology — Posted on 2024-11-04
4363 Machine learning engineered PoLixNano nanoparticles overcome delivery barriers for nebulized mRNA therapeutics
Zhang, D.; Xiao, Q.; Tang, J.; Xiao, K.; Chen, T.; Chen, Y.; Liu, Y.; Xu, L.; Li, C.; Cai, L.; Huang, S.; Wang, Y.; Peng, L.; Rosenecker, J.; Shao, D.; Zou, Q.; Guan, S.
10.1101/2024.11.03.621713 — synthetic biology — Posted on 2024-11-04
4364 H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress
Akter, S.; Perri, M.; Lavilla-Puerta, M.; Ferretti, B.; Dalle Carbonare, L.; Shukla, V.; Telara, Y.; Zhang, D.; Gunawardana, D. M.; Myers, W. K.; Giuntoli, B.; Flashman, E.; Licausi, F.
10.1101/2024.10.21.619351 — plant biology — Posted on 2024-11-04
4367 Designed miniproteins potently inhibit and protect against MERS-CoV
Ragotte, R. J.; Tortorici, M. A.; Cantazaro, N. J.; Addetia, A.; Coventry, B.; Froggatt, H. M.; Lee, J.; Stewart, C.; Brown, J. T.; Goreshnik, I.; Sims, J. N.; Milles, L. F.; Wicky, B. I.; Gloegl, M.; Gerben, S.; Kang, A.; Bera, A. K.; Sharkey, W.; Schaefer, A.; Baric, R. S.; Baker, D.; Veesler, D.
10.1101/2024.11.03.621760 — biochemistry — Posted on 2024-11-04
4368 Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β
Weaver, T. M.; Ryan, B. J.; Thompson, S. H.; Hussen, A. S.; Spencer, J. J.; Xu, Z.; Schnicker, N. J.; Freudenthal, B. D.
10.1101/2024.11.04.621902 — biochemistry — Posted on 2024-11-04
4369 Variations in kinase and effector signaling logic in a two component signaling network
Swingle, D.; Epstein, L.; Aymon, R.; Isiorho, E. A.; Abzalimov, R. R.; Favaro, D. C.; Gardner, K. H.
10.1101/2024.11.04.621962 — biochemistry — Posted on 2024-11-04
4371 Self-organization of spermatogenic wave coordinates sustained sperm production in the mouse testis
Sato, T.; Li, Y. I.; Jorg, D. J.; Komeya, M.; Yamanaka, H.; Nakamura, H.; Hirano, K.; Kondo, Y.; Aoki, K.; Takahashi, M.; Nakata, H.; Kimura, H.; Ogawa, T.; Simons, B. D.; Yoshida, S.
10.1101/2024.11.03.621757 — developmental biology — Posted on 2024-11-04
4373 CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
Samelson, A. J.; Ariqat, N.; McKetney, J.; Rohanitazangi, G.; Parra Bravo, C.; Bose, R.; Travaglini, K. J.; Lam, V. L.; Goodness, D.; Dixon, G.; Marzette, E.; Jin, J.; Tian, R.; Tse, E.; Abskharon, R.; Pan, H.; Carroll, E. C.; Lawrence, R. E.; Gestwicki, J. E.; Eisenberg, D.; Kanaan, N. M.; Southworth, D. R.; Gross, J. D.; Gan, L.; Swaney, D. L.; Kampmann, M.
10.1101/2023.06.16.545386 — cell biology — Posted on 2024-11-04
4376 Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding
Mathews, E. W.; Coffey, S. R.; Gaertner, A.; Belgrad, J.; Bragg, R. M.; O'Reilly, D.; Cantle, J. P.; McHugh, C.; Summers, A.; Fentz, J.; Schwagarus, T.; Cornelius, A.; Lingos, I.; Burch, Z.; Kovalenko, M.; Andrew, M. A.; Bennett, C. F.; Kordasiewicz, H.; Marchionini, D. M.; Wilkinson, H.; Vogt, T. F.; Pinto, R. M.; Khvorova, A.; Howland, D.; Wheeler, V.; Carroll, J. B.
10.1101/2024.11.04.619693 — neuroscience — Posted on 2024-11-04
4378 dArc1 controls sugar reward valuation in Drosophila melanogaster
Caron, S. J. C.; Bervoets, S.; Jacob, M. S.; Devineni, A.; Mahoney, B. D.; Sullivan, K. R.; Butts, A. R.; Sung, H.; Einstein, J.; Metzstein, M. M.; Dus, M.; Shepherd, J. D.
10.1101/2024.11.04.621761 — neuroscience — Posted on 2024-11-04
4379 Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability
Ruiz Coca, M.; Perez-Fernandez, C.; Abreu, A.; Salmeron, A.; Morales-Navas, M.; Ruiz-Sobremazas, D.; Colomina, T.; Fernandez, I.; Sanchez-Santed, F.
10.1101/2024.11.04.621795 — neuroscience — Posted on 2024-11-04
4386 Brain-wide population activity during reaching integrates action-mediated goal expectation
Peng, Y.; Lindersson, C.; Tinelli, S.; Stedehouder, J.; Shah, R. S.; Lak, A.; Stagg, C. J.; Sharott, A.
10.1101/2024.11.04.621878 — neuroscience — Posted on 2024-11-04
4388 Volume conductor models for magnetospinography
O'Neill, G. C.; Spedden, M. E.; Schmidt, M.; Mellor, S.; Stenroos, M.; Barnes, G. R.
10.1101/2024.11.04.621905 — neuroscience — Posted on 2024-11-04
4389 F2,6BP restores mitochondrial genome integrity in Huntingtons Disease
Chakraborty, A.; Mandal, S. M.; Mankevich, M.; Sreenivasmurthy, S. G.; Hegde, M.; Ghosh, G.; Hazra, T.
10.1101/2024.11.04.621834 — neuroscience — Posted on 2024-11-04
4391 MINT: a toolbox for the analysis of multivariate neural information coding and transmission
Lorenz, G. M.; Engel, N. M.; Celotto, M.; Kocillari, L.; Curreli, S.; Fellin, T.; Panzeri, S.
10.1101/2024.11.04.621910 — neuroscience — Posted on 2024-11-04
4395 Age and amyloidβ-dependent initiation of neurofibrillary tau tangles: an improved mouse model of Alzheimers disease without mutations in MAPT.
Desai, S.; Camporesi, E.; Brinkmalm, G.; Alatza, A.; Wood, J. I.; Tripathi, T.; Bez, S.; Stasyuk, N.; Hajar, H. B.; Saito, T.; Saido, T. C.; Hardy, J.; Cummings, D. M.; Hanrieder, J.; Edwards, F. A.
10.1101/2024.11.04.621900 — neuroscience — Posted on 2024-11-04
4397 ASD-ASSOCIATED CNTNAP2 VARIANTS DISRUPT NEURONAL ARBORIZATION THROUGH IMPAIRED REGULATION BY ECTODOMAIN SHEDDING
Lobete, M.; Dionisio, L. E.; McCoig, E.; Piguel, N. H.; Socas, S.; do Santos, M.; Boers-Escuder, C.; Penzes, P.; Martin-de-Saavedra, M. D.
10.1101/2024.11.04.621898 — neuroscience — Posted on 2024-11-04
4400 Genomic characterization of foodborne Salmonella enterica and Escherichia coli isolates from Saboba district and Bolgatanga Municipality Ghana
Sunmonu, G. T.; Adzitey, F.; Odih, E. E.; Tibile, B. A.; Ekli, R.; Aduah, M.; Oaikhena, A. O.; Akinlabi, O. C.; Abia, A. L. K.; Amoako, D. G.; Okeke, I. N.
10.1101/2024.09.05.611394 — microbiology — Posted on 2024-11-04
4402 Basal forebrain activation improves working memory in senescent monkeys
Pennington, K. R.; Debs, L.; Chung, S.; Bava, J. M.; Garin, C.; Vale, F. L.; Bick, S. K.; Englot, D. J.; Terry, A. V.; Constantinidis, C.; Blake, D. T.
10.1101/2024.03.01.582925 — neuroscience — Posted on 2024-11-04
4403 Sigh generation in preBötzinger Complex
Cui, Y.; Bondarenko, E.; Thörn Perez, C.; Chiu, D. N.; Feldman, J. L.
10.1101/2024.06.05.597565 — neuroscience — Posted on 2024-11-04
4404 Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny
Hunt, M.; Hinrichs, A. S.; Anderson, D.; Karim, L.; Dearlove, B. L.; Knaggs, J.; Constantinides, B.; Fowler, P. W.; Rodger, G.; Street, T. L.; Lumley, S. F.; Webster, H.; Sanderson, T.; Ruis, C.; Kotzen, B.; De Maio, N.; Amenga-Etego, L. N.; Amuzu, D. S.; Avaro, M.; Awandare, G. A.; Ayivor-Djanie, R.; Barkham, T.; Bashton, M.; Batty, E. M.; Bediako, Y.; De Belder, D.; Benedetti, E.; Bergthaler, A.; Boers, S. A.; Campos, J.; Carr, R. A. A.; Chen, Y. Y. C.; Cuba, F.; Dattero, M. E.; Dejnirattisai, W.; Dilthey, A. T.; Duedu, K. O.; Endler, L.; Engelmann, I.; Francisco, N. M.; Fuchs, J.; Gnimpieba
10.1101/2024.04.29.591666 — bioinformatics — Posted on 2024-11-04
4406 Macroevolutionary inference of complex modes of chromosomal speciation in a cosmopolitan plant lineage
Tribble, C. M.; Marquez Corro, J. I.; May, M. R.; Hipp, A. L.; Escudero, M.; Zenil-Ferguson, R.
10.1101/2023.09.05.556433 — evolutionary biology — Posted on 2024-11-04
4407 The molecular chronology of mammary epithelial cell fate switching
Vallmajo-Martin, Q.; Ma, Z.; Srinivasan, S.; Murali, D.; Dravis, C.; Mukund, K.; Subramaniam, S.; Wahl, G. M.; Lytle, N. K.
10.1101/2024.10.08.617155 — cell biology — Posted on 2024-11-04
4409 Mitochondrial Phosphopantetheinylation is Required for Oxidative Function
Norden, P. R.; Wedan, R. J.; Longenecker, J. Z.; Preston, S. E. J.; Graber, N.; Ols, O.; Canfield, M.; McLaughlin, E.; Nowinski, S. M.
10.1101/2024.05.09.592977 — molecular biology — Posted on 2024-11-04
4410 Protocols for circulating neutrophil depletion in neonatal C57Bl/6 mice
Mukherjee, D.; Satyavolu, S.; Cioffi, S.; Thomas, A.; Li, Y.; Nayak, L.
10.1101/2024.05.06.592835 — immunology — Posted on 2024-11-04
4411 Orthogonal spectral and temporal envelope representation in auditory cortex
Takahashi, K.; Guo, T.; Yamagishi, T.; Ohshima, S.; Tsukano, H.; Horii, A.
10.1101/2024.10.28.620417 — neuroscience — Posted on 2024-11-04
4416 HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data
Mao, H.; Jia, M.; Di, M.; Valenzi, E.; Cai, X. T.; Singh, H.; Lafyatis, R. A.; Zhang, K.; Benos, P. V.
10.1101/2022.10.17.512602 — bioinformatics — Posted on 2024-11-04
4417 Analysis of sparse animal social networks
Mylne, H. K.; Abell, J.; Beale, C. M.; Brent, L. J. N.; Bro-Jorgensen, J.; Evans, K. E.; Hart, J. D. A.; Sakala, D.; Simpamba, T.; Youldon, D.; Franks, D. W.
10.1101/2024.10.31.621436 — animal behavior and cognition — Posted on 2024-11-04
4420 Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila
Held, M.; Bisen, R. S.; Zandawala, M. M.; Chockley, A. S.; Balles, I. S.; Hilpert, S.; Liessem, S.; Cascino-Milani, F.; Ache, J. M.
10.1101/2023.09.14.557555 — neuroscience — Posted on 2024-11-04
4426 Evolution in response to an abiotic stress shapes species coexistence
Fragata, I.; Godinho, D. P.; Rodrigues, L. R.; Cruz, M. A.; Zele, F.; Godoy, O.; Magalhaes, S.
10.1101/2023.05.06.539716 — evolutionary biology — Posted on 2024-11-04
4430 Autonomic and Immune Stress Response Networks in Patients Living With HIV
Mueller, B. R.; Mehta, M.; Campbell, M.; Neupane, N.; Cedillo, G.; Lee, G.; Coyle, K.; Qi, J.; Chen, Z.; George, M. C.; Robinson-Papp, J.
10.1101/2024.10.15.618447 — immunology — Posted on 2024-11-04
4431 Accelerated signal propagation speed in human neocortical dendrites
Olah, G.; Lakovics, R.; Shapira, S.; Leibner, Y.; Szucs, A.; Csajbok, E. A.; Barzo, P.; Molnar, G.; Segev, I.; Tamas, G.
10.1101/2022.09.30.510270 — neuroscience — Posted on 2024-11-04
4432 Dnajc3 (HSP40) Enhances Axon Regeneration in the Mouse Optic Nerve
Wang, J.; Li, Y.; Struebing, F. L.; Jardines, S.; Lin, S.-T.; Lin, F.; Geisert, E. E.
10.1101/2024.10.08.617251 — neuroscience — Posted on 2024-11-04
4434 Proteolysis-targeting vaccines (PROTAVs) for robust combination immunotherapy of melanoma
Wang, Q.; Su, T.; Cheng, F.; Zhou, S.; Liu, X.; Wang, M.; Tang, R.; Xu, Y.; Liao, S.; Dailey, J.; Xiao, G.; Wen, H.; Zheng, w.; Wen, B.; Katarzyna, T. M.; Liu, J.; Sun, D.; Wang, S.; Zhu, G.
10.1101/2024.10.01.616069 — bioengineering — Posted on 2024-11-04
4435 Protein generation with evolutionary diffusion: sequence is all you need
Alamdari, S.; Thakkar, N.; van den Berg, R.; Tenenholtz, N.; Strome, B.; Moses, A.; Lu, A. X.; Fusi, N.; Amini, A. P.; Yang, K. K.
10.1101/2023.09.11.556673 — bioengineering — Posted on 2024-11-04
4436 A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS
Nourreddine, S.; Doctor, Y.; Dailamy, A.; Forget, A.; Lee, Y.-H.; Chinn, B.; Khaliq, H.; Polacco, B.; Muralidharan, M.; Pan, E.; Zhang, Y.; Sigaeva, A.; Hansen, J. N.; Gao, J.; Parker, J. A.; Obernier, K.; Clark, T.; Chen, J. Y.; Metallo, C.; Lundberg, E.; Ideker, T.; Krogan, N.; Mali, P.
10.1101/2024.11.03.621734 — bioengineering — Posted on 2024-11-04
4439 Probing other's Presence: Probabilistic Inference Across Brain Scales Reveals Enhanced Excitatory Synaptic Efficacy
Esmaeili, A.; Demolliens, M.; Viersen, M.; Ziaeemehr, A.; Isbaine, F.; Huguet, P.; Zaal, F.; Jirsa, V.; Boussaoud, D.; Hashemi, M.
10.1101/2024.09.09.612006 — neuroscience — Posted on 2024-11-04
4440 MethylGPT: a foundation model for the DNA methylome
Ying, K.; Song, J.; Cui, H.; Zhang, Y.; Li, S.; Chen, X.; Liu, H.; Eames, A.; McCartney, D. L.; Marioni, R. E.; Poganik, J. R.; Moqri, M.; Wang, B.; Gladyshev, V. N.
10.1101/2024.10.30.621013 — systems biology — Posted on 2024-11-04
4441 Identification and annotation of centromeric hypomethylated regions with Centromere Dip Region (CDR)-Finder
Mastrorosa, F. K.; Oshima, K. K.; Rozanski, A. N.; Harvey, W. T.; Eichler, E. E.; Logsdon, G. A.
10.1101/2024.11.01.621587 — genomics — Posted on 2024-11-04
4443 Strip cropping designed for maintaining productivity increases ground beetle biodiversity
Croijmans, L.; Cuperus, F.; van Apeldoorn, D. F.; Bianchi, F. J. J. A.; Rossing, W. A. H.; Poelman, E.
10.1101/2024.11.02.621655 — ecology — Posted on 2024-11-04
4445 Molecular Signatures of Resilience to Alzheimer's Disease in Neocortical Layer 4 Neurons
Dharshini, S. A. P.; Sanz-Ros, J.; Pan, J.; Tang, W.; Vallejo, K.; Otero-Garcia, M.; Cobos, I.
10.1101/2024.11.03.621787 — neuroscience — Posted on 2024-11-04
4449 High life history diversity within a single genus of phytoplankton viruses
Lievens, E. J.; Agarkova, I. V.; Dunigan, D. D.; Van Etten, J. L.; Becks, L.
10.1101/2022.03.13.484168 — evolutionary biology — Posted on 2024-11-04
4452 A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS
Nourreddine, S.; Doctor, Y.; Dailamy, A.; Forget, A.; Lee, Y.-H.; Chinn, B.; Khaliq, H.; Polacco, B.; Muralidharan, M.; Pan, E.; Zhang, Y.; Sigaeva, A.; Hansen, J. N.; Gao, J.; Parker, J. A.; Obernier, K.; Clark, T.; Chen, J. Y.; Metallo, C.; Lundberg, E.; Ideker, T.; Krogan, N.; Mali, P.
10.1101/2024.11.03.621734 — bioengineering — Posted on 2024-11-04
4453 ENDO-LYSOSOME-TARGETED NANOPARTICLE DELIVERY OF ANTIVIRAL THERAPY FOR CORONAVIRUS INFECTIONS
Petcherski, A.; Tingley, B.; Martin, A.; Adams, S.; Brownstein, A.; Steinberg, R.; Shabane, B.; Osto, C.; Ngo, J.; Garcia, G.; Veliova, M.; Arumugaswami, V.; Colby, A.; Shirihai, O.; Grinstaff, M.
10.1101/2023.05.08.539898 — bioengineering — Posted on 2024-11-04
4454 Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms
Bowden, S.; Brislinger-Engelhardt, M. M.; Hansen, M.; Temporal Plo, A.; Weber, D.; Haegele, S. L.; Lorenz, F.; Litwin, T.; Kreutz, C.; Walentek, P.
10.1101/2024.10.27.620464 — developmental biology — Posted on 2024-11-04
4459 Intelligence and Cognitive Flexibility Selectively Modulate Working Memory Functioning
Zhang, H.; Meng, C.; Xu, X.; Hu, X.; Zhang, Z.; Klugah-Brown, B.; Biswal, B. B.
10.1101/2024.10.30.620994 — neuroscience — Posted on 2024-11-04
4462 Object-translocation induces event coding in the hippocampus
Duan, Y.-L.; Hu, S.-Y.; Ge, X.-F.; Long, J.-L.; Deng, C.; Sun, Y.-M.; Li, C.-J.; Zhang, R.; Cai, X.; Lu, L.
10.1101/2024.06.06.597717 — neuroscience — Posted on 2024-11-04
4463 Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability
Sannigrahi, M. K.; Raghav, L.; Rich, D. J.; Schrank, T. P.; Califano, J. A.; Lukens, J. N.; Sun, L.; Morgan, I. M.; Cohen, R. B.; Lin, A.; Liu, X.; Brown, E. J.; You, J.; Mirabello, L.; Mishra, S. K.; Shimunov, D.; Brody, R. M.; Pearson, A. T.; Gimotty, P. A.; Diab, A.; Jalaly, J. B.; Basu, D.
10.1101/2024.10.31.621311 — cancer biology — Posted on 2024-11-04
4466 Polymorphic tandem repeats shape single-cell gene expression across the immune landscape
Tanudisastro, H. A.; Cuomo, A. S. E.; Weisburd, B.; Welland, M.; Spenceley, E.; Franklin, M.; Xue, A.; Bowen, B.; Wing, K.; Tang, O.; Gray, M.; Reis, A. L. M.; Margoliash, J.; Kurtas, E. N.; Pullin, J.; Lee, A. S.; Brand, H.; Harper, M.; Bobowik, K.; Silk, M.; Marshall, J.; Bakiris, V.; Swapna Madala, B.; Uren, C.; Bartie, C.; Senabouth, A.; Dashnow, H.; Fearnley, L.; Dolzhenko, E.; Qiao, Z.; Grieve, S.; Nguyen, T.; Talkowski, M.; Alexander, S. I.; Siggs, O. M.; Gruenschloss, L.; Nicholas, H. R.; Piscionere, J.; Simons, C.; Wallace, C.; Gymrek, M.; Deveson, I. W.; Hewitt, A. W.; Figtree, G. A.
10.1101/2024.11.02.621562 — genomics — Posted on 2024-11-04
4469 Inhibition of Yes-Associated Protein (YAP) with Verteporfin Enhances Radiosensitivity in Chordoma by Inducing G2M Arrest and Inhibiting the DNA Damage Response
Akinduro, O. O.; Meade, P. S.; Schiapparelli, P.; Whitehead, R.; Tzeng, S. Y.; Rosenfeld, S. S.; Kim, S.; Palena, C.; Gokaslan, Z. L.; Green, J. J.; Hinojosa, A. Q.
10.1101/2024.11.03.621728 — cancer biology — Posted on 2024-11-04
4470 Tumoral hypoxic extracellular vesicles create a protective microenvironment for triple-negative breast cancer
Pachane, B. C.; Bottaro, P. H. T.; Machado, A. M.; Castro, C. A.; Guerra, G.; Gozzer, L. T.; Grigoli, M. M.; Zutiao, A. D.; Fuzer, A. M.; Cominetti, M. R.; Altei, W. F.; Selistre-de-Araujo, H. S.
10.1101/2024.11.01.621519 — cancer biology — Posted on 2024-11-04
4471 Reinforced identity confers cells with cancer hallmarks
Yang, H.; Wang, P.; Tan, P.; Xue, Q.; Wu, H.; He, K.; Wang, B.; Wang, D.; Ma, T.; Ding, S.
10.1101/2024.11.01.621626 — cancer biology — Posted on 2024-11-04
4474 Deep generative model for protein subcellular localization prediction
Yuan, G.-H.; Li, J.; Yang, Z.; Chen, Y.-Q.; Yuan, Z.; Chen, T.; Ouyang, W.; Dong, N.; Yang, L.
10.1101/2024.10.29.620765 — bioinformatics — Posted on 2024-11-03
4477 Programmable 3D cell alignment of bioprinted tissue via soft robotic dynamic stimulation
Rosalia, L.; Mosle, K.; Sinha, S.; Du, Y. Y.; Solberg, F.; Jia, A.; Weiss, J.; Tam, T.; Herrmann, J. E.; Cutkosky, M.; Skylar-Scott, M.
10.1101/2024.11.03.621771 — bioengineering — Posted on 2024-11-04
4489 Stacked Human Arterial Endothelial Cells Generate Atherosclerotic Fatty Streaks and Release Proinflammatory Cytokines
Zeng, Y.; Ouyang, Z.; Qiu, Y.; Jiang, W.; Jin, C.; Zhong, J.; Jin, L.; Qin, Y.; Zhao, Y.; Zhou, X.; Liu, X.; Fu, B. M.
10.1101/2024.11.03.621780 — cell biology — Posted on 2024-11-04
4490 Requirement for Fc effector function is overcome by binding potency for broadly reactive anti-alphavirus antibodies
Callahan, V.; Sutton, M.; Gardner, C. L.; Kenchegowda, D.; Dunagan, M. M.; Gosavi, M.; Green, C.; Chen, T. Y.; Prado-Smith, J.; Long, D.; Vogel, J. L.; Kristie, T. M.; Clancy, C. S.; Burke, C. W.; Roederer, M.; Fox, J. M.
10.1101/2024.11.03.619087 — microbiology — Posted on 2024-11-03
4491 Amphiphile-engineered DNA adjuvants stimulate strong type I IFN production in lymph nodes via cytosolic danger-sensing to induce potent cellular and humoral immunity in mice and non-human primates
Steinbuck, M. P.; Seenappa, L. M.; Zhan, W.; Palmer, E.; Jakubowski, A.; Cabana-Puig, X.; Jung, M. M.; McNeil, L. K.; Haqq, C. M.; Fitzgerald, K. A.; DeMuth, P. C.
10.1101/2024.11.01.621501 — immunology — Posted on 2024-11-03
4492 Low Dose Radiation by Radiopharmaceutical Therapy Enhances GD2 TRAC-CAR T Cells Efficacy in Localized Neuroblastoma
Sodji, Q. H.; Shea, A.; Cappabianca, D.; Forsberg, M. H.; Eickhoff, J. C.; Idrissou, M.; Ollendorff, A. S.; Kwon, O.; Ong, I. M.; Hernandez, R. T.; Weichert, J.; Bednarz, B.; Saha, K.; Sondel, P. M.; Capitini, C. M.; Morris, Z. S.
10.1101/2024.11.02.621668 — immunology — Posted on 2024-11-03
4495 Synchronous activation of striatal cholinergic interneurons induces local serotonin release
Matityahu, L.; Hobel, Z. B.; Berkowitz, N.; Malgady, J. M.; Gilin, N.; Plotkin, J. L.; Goldberg, J. A.
10.1101/2024.11.03.621726 — neuroscience — Posted on 2024-11-04
4496 Mitochondrial efficiency determines Crabtree effect across yeasts
Battjes, J.; Grigaitis, P.; Hoving, M.; Visser, T.; Stampfl, K.; Miguel, G.; van Heerden, J. H.; Andersen, J.; Bruggeman, F.; Teusink, B.
10.1101/2024.11.01.621473 — systems biology — Posted on 2024-11-03
4498 Centromeric repeat diversity underlies non-Mendelian segregation pattern in hop (Humulus lupulus)
Horakova, L.; Cegan, R.; Jedlicka, P.; Navratilova, P.; Tanaka, H.; Toyoda, A.; Itoh, T.; Akagi, T.; Ono, E.; Hudzieczek, V.; Patzak, J.; Safar, J.; Hobza, R.; Bacovsky, V.
10.1101/2024.11.03.621702 — plant biology — Posted on 2024-11-03
4499 Hypoxia exposure fine-tunes mitochondrial function in sea turtle cells
Arango, B. G.; Ensminger, D. C.; Xing, D.; Godard-Codding, C. A.; Vazquez-Medina, J. P.
10.1101/2024.11.01.621592 — physiology — Posted on 2024-11-03
4502 IKAROS facilitates antigen escape in the face of CD19- and CD22-targeted therapies for B-cell acute lymphoblastic leukemia
Domizi, P.; Sarno, J.; Jager, A.; Merchant, M.; Pacheco, K. Z. B.; Yamada-Hunter, S. A.; Rotiroti, M. C.; Liu, Y.; Baskar, R.; Reynolds, W. D.; Sworder, B. J.; Sahaf, B.; Bendall, S. C.; Mullighan, C. G.; Alizadeh, A. A.; Leahy, A. B.; Myers, R. M.; Yates, B.; Wang, H.-W.; Shah, N. N.; Majzner, R. G.; Mackall, C. L.; Grupp, S. A.; Barrett, D. M.; Sotillo, E.; Davis, K. L.
10.1101/2024.11.01.621347 — cancer biology — Posted on 2024-11-03
4504 Inhibition of H3K27M-enhanced ATM signaling increases radiation efficacy in diffuse midline glioma
Peterson, E. R.; Parsels, L. A.; Parsels, J. D.; Zhao, X.; Castro, M. G.; Lawrence, T. S.; Koschmann, C.; Zhang, Q.; Wahl, D. R.; Morgan, M. A.
10.1101/2024.11.01.621526 — cancer biology — Posted on 2024-11-03
4505 Disease-linked mutations dysregulate neuronal condensate physical properties, composition, and RNA translation
Ahangama Liyanage, L.; McCready, F.; Chung, S.; Arsenault, J.; Wei, W.; Lin, X.; Wang, L.-Y.; Ellis, J.; Ditlev, J. A.
10.1101/2024.11.01.621623 — biophysics — Posted on 2024-11-03
4508 FIBOS: R and Python packages for analyzing protein packing and structure
Soares, H. H. M.; Romanelli, J. P. R.; Fleming, P. J.; Silveira, C. H. d.
10.1101/2024.11.01.621530 — bioinformatics — Posted on 2024-11-03
4515 Antibody Library Design by Seeding LinearProgramming with Inverse Folding and ProteinLanguage Models
Hayes, C. F.; Magana-Zook, S. A.; Goncalves, A.; Solak, A. C.; Faissol, D.; Landajuela, M.
10.1101/2024.11.03.621763 — bioinformatics — Posted on 2024-11-03
4516 Transcriptome Analysis of Archived Tumor Tissues by Visium, GeoMx DSP, and Chromium Methods Reveals Inter- and Intra-Patient Heterogeneity
Dong, Y.; Saglietti, C.; Bayard, Q.; Perez, A. E.; Carpentier, S.; Buszta, D.; Tissot, S. R.; Dubois, R.; Kamburov, A.; Kang, S.; Haignere, C.; Sarkis, R.; Andre, S.; Gaveta, M. A.; Lastra, S. L.; Piazzon, N.; Santos, R.; von Loga, K.; Hoffmann, C.; Coukos, G.; Peters, S.; Soumelis, V.; Durand, E. Y.; de Leval, L.; Gottardo, R.; Homicsko, K.; Madissoon, E.
10.1101/2024.11.01.621259 — bioinformatics — Posted on 2024-11-03
4517 Data driven refinement of gene expression signatures for enrichment analysis
Wenzel, A. T.; Faraji, F.; Sato, K.; Medetgul-Ernar, K.; Castanza, A.; Sagatelian, R.; Donepudi, G.; Halawa, O.; Wang, J. Y. J.; Gutkind, J. S.; Tamayo, P.; Mesirov, J. P.
10.1101/2024.11.03.621768 — bioinformatics — Posted on 2024-11-03
4518 Generalized cell phenotyping for spatial proteomics with language-informed vision models
Wang, X.; Dilip, R.; Bussi, Y.; Brown, C.; Pradhan, E.; Jain, Y.; Yu, K.; Li, S.; Abt, M.; Borner, K.; Keren, L.; Yue, Y.; Barnowski, R.; Van Valen, D. A.
10.1101/2024.11.02.621624 — bioinformatics — Posted on 2024-11-03
4519 Quantification of thermal side effects during pulsed field ablation
Mercado Montoya, M.; Gomez Bustamante, T.; Mickelsen, S.; Kulstad, E.; Gonzalez Suarez, A.; Overzet, L. J.
10.1101/2024.11.02.621664 — bioengineering — Posted on 2024-11-03
4521 qByte: Open-source isothermal fluorimeter for democratizing analysis of nucleic acids, proteins and cells
Lombardero, F. J. Q.; Aidelberg, G.; Vielfaure, H.; de Kermadec, Y. H.; Cazaux, S.; Pandi, A.; Pascual-Garrigos, A.; Arce, A.; Sakyi, S. A.; Gaudenz, U.; Federici, F.; Molloy, J. C.; Lindner, A. B.
10.1101/2024.11.03.621723 — bioengineering — Posted on 2024-11-03
4522 Non-invasive imaging of cell-based therapies using acoustic reporter genes
Shivaei, S.; Liu, A.; Abedi, M. H.; Revilla, J.; Hurvitz, I. U.; Swift, M. B.; Shapiro, M. G.
10.1101/2024.11.01.621111 — bioengineering — Posted on 2024-11-03
4525 In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging
Dure, C.; Ghoshdastider, U.; Weber, R.; Valdivia-Francia, F.; Renz, P. F.; Khandekar, A.; Sella, F.; Hyams, K.; Taborsky, D.; Yigit, M.; Ormiston, M.; Yamahachi, H.; Levesque, M.; Ellis, S. J.; Sendoel, A.
10.1101/2024.11.02.621639 — genomics — Posted on 2024-11-03
4526 A pluripotent stem cell atlas of multilineage differentiation reveals TMEM88 as a developmental regulator of mammalian blood pressure
Shen, S.; Werner, T.; Lukowski, S.; Andersen, S.; Sun, Y.; Shim, W. J.; Mizikovsky, D.; Kobayashi, S.; Outhwaite, J.; Chiu, H. S.; Chen, X.; Chapman, G.; Martin, E. M. M. A.; Xia, D.; Pham, D.; Su, Z.; Kim, D.; Yang, P.; Tan, M. C.; Sinniah, E.; Zhao, Q.; Negi, S.; Redd, M. A.; Powell, J. E.; Dunwoodie, S. L.; Tam, P. P. L.; Boden, M.; Ho, J. W. K.; Nguyen, Q.; Palpant, N. J.
10.1101/2022.10.12.511862 — genomics — Posted on 2024-11-03
4529 A generic pipeline for CADD score generation: chickenCADD and turkeyCADD
Lensing, K.; van Schipstal, J. G. C.; de Ridder, D.; Groenen, M.; Derks, M.
10.1101/2024.11.01.621569 — genomics — Posted on 2024-11-03
4531 Transcriptome analysis of atad3-null zebrafish embryos elucidates possible disease mechanisms
Ezer, S.; Ronin, N.; Yanovsky-Dagan, S.; Rotem-Bamberger, S.; Halstuk, O.; Wexler, Y.; Ben-Moshe, Z.; Plaschkes, I.; Benyamini, H.; Saada, A.; Inbal, A.; Harel, T.
10.1101/2024.11.02.621207 — genetics — Posted on 2024-11-03
4534 Environmental DNA and wildlife camera traps uncover complimentary vertebrate visitation patterns at freshwater granite rock-holes
Hedges, B. A.; Beasley-Hall, P. G.; Berry, T. E.; Dawkins, K. L.; Austin, A. D.; Weinstein, P.; Guzik, M. T.
10.1101/2024.10.31.621266 — ecology — Posted on 2024-11-03
4535 Mapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers
Kuhlisch, C.; Schleyer, G.; Flores, J. M.; Vincent, F.; Vallet, M.; Schatz, D.; Vardi, A.
10.1101/2024.11.03.621239 — ecology — Posted on 2024-11-03
4536 Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles
Singh, N. J.; Olofsson, R.; van der Meiden, A. J.; Lopez-Peinado, A.; Mansson, J.
10.1101/2024.11.02.621680 — ecology — Posted on 2024-11-03
4540 SUV39H1 mediated regulation of KLF4 and KDM4A coordinate smooth muscle cell phenotypic plasticity
Chatterjee, P.; Chakraborty, R.; Sizer, A.; O'Brien, B. J.; Xie, Y.; Hwa, J.; Martin, K. A.
10.1101/2024.11.03.621725 — cell biology — Posted on 2024-11-03
4542 Differential Regulation of Large-scale Chromosome Conformations in Osteoblasts and Osteosarcoma
Bisht, M.; Chung, Y.-C.; He, S.-L.; Willey, S.; Sunkel, B. D.; Wang, M.; Stanton, B.; Tu, L.-C.
10.1101/2024.11.01.621571 — cell biology — Posted on 2024-11-03
4543 C1q in non-immune human serum has a non-redundant complement function towards clinical Mycobacterium tuberculosis complex strains
Duque, M. A.; Goetz, M. P.; Rousseau, E.; Homolka, S.; Niemann, S.; Garred, P.; Hoelscher, C.; Walter, K.; Rosbjerg, A.
10.1101/2024.11.01.621467 — immunology — Posted on 2024-11-03
4546 PGR5 is needed for redox-dependent regulation of ATP synthase both in chloroplasts and in cyanobacteria
Nikkanen, L.; Wey, L. T.; Woodford, R.; Mustila, H.; Ermakova, M.; Rintamäki, E.; Allahverdiyeva, Y.
10.1101/2024.11.03.621747 — plant biology — Posted on 2024-11-03
4548 Phytoassisted synthesis of biogenic silver nanoparticles using Vernonia amygdalina leaf extract: characterization, antibacterial, anti-inflammatory, and acute toxicity profile
Nyuyfoni, G. F.; Nkana, B. P.; Deli, V.; Kedi, P. B. E.; Ntoumba, A. A.; Nanga, C. C.; Tchatchouang, G. C.; Djuidje, A. G.; Djimefo, T. A. K.; Evouna, I. D. M.; Malolo, E. F.-A.; Eha-Kang, C.; Kwati, L.; Ndzeidze, G. N.; Gbambie, A. P.; Francois, E. M.
10.1101/2024.10.31.621348 — pharmacology and toxicology — Posted on 2024-11-03
4549 Leukemia confers a durable imprint on healthy hematopoietic stem and progenitor cells
Chen, D.-W.; Schrey, J. M.; Fan, J.-M.; Adams, S. E.; Taylor, D. M.; Wafula, E. K.; Kurre, P.
10.1101/2024.11.01.621509 — cancer biology — Posted on 2024-11-03
4550 A unique malignant cell type per patient tumor is encoded in each cancer cell transcriptome.
Saurty-Seerunghen, M. S.; El-Habr, E. A.; Eliaz, Y.; Bellenger, L.; Antoniewski, C.; Chneiweiss, H.; Junier, M.-P.
10.1101/2024.10.30.620989 — cancer biology — Posted on 2024-11-03
4551 An alternative route for β-hydroxybutyrate metabolism supports fatty acid synthesis in cancer cells
Kaluba, F. C.; Rogers, T. J.; Jeong, Y.-J.; Waldhart, A.; Sokol, K. H.; Lee, C. J.; Daniels, S. R.; Longo, J.; Johnson, A.; Sheldon, R. D.; Jones, R. G.; Lien, E. C.
10.1101/2024.10.31.621317 — cancer biology — Posted on 2024-11-03
4553 Local ionic conditions modulate the aggregation propensity and influence the structural polymorphism of alpha-synuclein
Zacharopoulou, M.; Seetaloo, N.; Ross, J.; Stephens, A. D.; Fusco, G.; McCoy, T.; Dai, W.; Mela, I.; Martel, A.; Fernandez-Villegas, A.; Routh, A. F.; De Simone, A.; Phillips, J. J.; Schierle, G. S. K.
10.1101/2024.11.03.621709 — biophysics — Posted on 2024-11-03
4554 Structural Basis of GPCR-G Protein Pre-coupling and Activation: Insights from CCR1-Gi Complex
Shao, Z.; Dong, Y.; Jia, R.; Shen, Q.; Yao, B.; He, X.; Yuan, Q.; Shen, D.-D.; Mao, C.; Zhang, C.; Chen, Z.-H.; Xu, H. E.; Ying, S.; Zhang, Y.; Li, W.
10.1101/2024.11.01.621549 — biophysics — Posted on 2024-11-03
4555 Revised diffusion law permits quantitative nanoscale characterization of membrane organization
Svobodova, B.; Stastny, D.; Blom, H.; Mikhalyov, D. I. I.; Gretskaya, D. N.; Ballekova, D. A.; Sezgin, D. E.; Hof, P. M.; Sachl, D. R.
10.1101/2024.11.01.621464 — biophysics — Posted on 2024-11-03
4558 GenoSiS: A Biobank-Scale Genotype Similarity Search Architecture for Creating Dynamic Patient-Match Cohorts
Schneider, K.; Chowdhury, M.; Tepper, M.; Khan, J. B.; Colorado Center for Personalized Medicine, ; Shortt, J. A.; Gignoux, C. R.; Layer, R. M.
10.1101/2024.11.02.621671 — bioinformatics — Posted on 2024-11-03
4559 Evaluation of T Cell Receptor Construction Methods from scRNA-Seq Data
Tian, R.; Yu, Z.; Xue, Z.; Wu, J.; Wu, L.; Cai, S.; Gao, B.; He, B.; Zhao, Y.; Yao, J.; Lu, L.; Liu, W.
10.1101/2024.11.01.621447 — bioinformatics — Posted on 2024-11-03
4560 Deep Gaussian Process with Uncertainty Estimation for Microsatellite Instability and Immunotherapy Response Prediction Based on Histology
Park, S.; Pettigrew, M. F.; Cha, Y. J.; Kim, I.-H.; Kim, M.; Banerjee, I.; Barnfather, I.; Clemenceau, J. R.; Jang, I.; Kim, H.; Kim, Y.; Pai, R. K.; Park, J. H.; Samadder, J. J.; Song, K. Y.; Sung, J.-Y.; Cheong, J.-H.; Kang, J.; Lee, S. H.; Wang, S. C.; Hwang, T. H.
10.1101/2024.11.01.621561 — bioinformatics — Posted on 2024-11-03
4564 Single-cell DNA methylome and 3D genome atlas of the human subcutaneous adipose tissue
Chen, Z. J.; Das, S. S.; Kar, A.; Lee, S. H. T.; Abuhanna, K. D.; Alvarez, M.; Sukhatme, M. G.; Gelev, K. Z.; Heffel, M. G.; Zhang, Y.; Avram, O.; Rahmani, E.; Sankararaman, S.; Heinonen, S.; Peltoniemi, H.; Halperin, E.; Pietiläinen, K. H.; Luo, C.; Pajukanta, P.
10.1101/2024.11.02.621694 — genomics — Posted on 2024-11-03
4565 Kudoa genomes from contaminated hosts reveal extensive gene order conservation and rapid sequence evolution
Weber, C. C.; Paulini, M.; Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team, ; Wellcome Sanger Institute Tree of Life Core Informatics team, ; Blaxter, M. L.
10.1101/2024.11.01.621499 — genomics — Posted on 2024-11-03
4567 Transcriptional changes across tissue and time provide molecular insights into a therapeutic window of opportunity following traumatic stress exposure
McKibben, L. A.; Iyer, M. R.; Zhao, Y.; Florea, R.; Kuhl-Chimera, S.; Deliwala, I. H.; Pan, Y.; Branham, E. M.; Geranton, S. M.; McLean, S. A.; Linnstaedt, S. D.
10.1101/2024.11.01.621484 — genomics — Posted on 2024-11-03
4568 Bystander activation across a TAD boundary supports a cohesin-dependent hub-model for enhancer function
Williamson, W. I.; Graham, K. A.; Becher, H. I.; Hill, R. E.; Bickmore, W. A.; Lettice, L. A.
10.1101/2024.11.01.621524 — genetics — Posted on 2024-11-03
4577 Unanchored ubiquitin chains promote the non-canonical inflammasome via UBXN1
Yang, D.; Cahoon, J. G.; Geng, T.; Wang, C.; Harrison, a. G.; Teran, E.; Wang, Y.; Vella, A. T.; Rathinam, V. A.; Ruan, J.; WANG, P.
10.1101/2024.10.30.621131 — immunology — Posted on 2024-11-03
4578 ImmunoStruct: Integration of protein sequence, structure, and biochemical properties for immunogenicity prediction and interpretation
Givechian, K. B.; Rocha, J. F.; Yang, E.; Liu, C.; Greene, K.; Ying, R.; Caron, E.; Iwasaki, A.; Krishnaswamy, S.
10.1101/2024.11.01.621580 — immunology — Posted on 2024-11-03
4581 Effects of intergenerational transmission of small intestinal bacteria cultured from stunted Bangladeshi children with enteropathy
Pruss, K. M.; Kao, C.; Byrne, A. E.; Chen, R. Y.; Di Luccia, B.; Karvelyte, L.; Coskun, R.; Lemieux, M.; Nepal, K.; Webber, D. M.; Hibberd, M. C.; Wang, Y.; Rodionov, D. A.; Osterman, A.; Maueroder, C.; Ravichandran, K.; Barratt, M.; Ahmed, T.; Gordon, J.
10.1101/2024.11.01.621574 — systems biology — Posted on 2024-11-03
4582 Transcutaneous Vagus Nerve Stimulation Reduces Pain and OA Progression in Mouse Models of Post-Traumatic Osteoarthritis
Yadav, S.; Morris, L.; Connor, T.; Lumry, J.; South, S.; Prinz, E.; Izda, V. A.; Dyson, G.; Barrett, M.; Stravakis, S.; Griffin, T.; Jeffries, M. A.; Humphrey, M. B.
10.1101/2024.10.31.621385 — physiology — Posted on 2024-11-03
4583 The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular health
Dyson, N.; Khambata, R. S.; Parakaw, T.; Massimo, G.; Khuat, N. H. H.; Noor, A. A.; Gee, L. C.; Lim, I.; Siddique, U.; Sullivan, A. J.; Ho, J. W.-T.; Barnes, M. R.; Cabrera, C. P.; Ahluwalia, A.
10.1101/2024.11.01.621390 — pharmacology and toxicology — Posted on 2024-11-03
4585 The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women
Ismail, S. D.; Sebaa, S.; Abrahams, B.; Nason, M. C.; Mumby, M. J.; Dikeakos, J. D.; Joseph, S. B.; Moeser, M.; Swanstrom, R.; Garrett, N.; Williamson, C.; Quinn, T. C.; Abrahams, M.-R.; Redd, A. D.
10.1101/2024.11.01.621615 — pathology — Posted on 2024-11-03
4587 Conditional activation of NK cell function using chemically synthetic constrained bicyclic peptides directed against NKp46 and tumor-expressed antigens
Dufort, F. J.; Leitheiser, C. J.; Rezvaya, A.; Ezell, T. R.; Ho, K. Q.; Bezerra, G. A.; Blakeman, B. J.; Stanczuk, L.; Brown, P. N.; Mudd, G. E.; McDonnell, K.; Keen, N.; Brandish, P.
10.1101/2024.10.30.621052 — cancer biology — Posted on 2024-11-03
4589 An integrative RNA spliceosomic landscape of pancreatic neuroendocrine tumors unveils novel clinicomolecular associations
Blazquez-Encinas, R.; Garcia-Vioque, V.; Mafficini, A.; Landoni, L.; Moreno-Montilla, M. T.; Alcala, N.; Ventura, S.; Eyras, E.; Paiella, S.; Salvia, R.; Rovite, V.; Foll, M.; Luchini, C.; Fernandez-Cuesta, L.; Lawlor, R. T.; Scarpa, A.; Ibanez-Costa, A.; Pedraza-Arevalo, S.; Castano, J. P.
10.1101/2024.10.30.621040 — cancer biology — Posted on 2024-11-03
4591 ADAT2/3-mediated tRNA editing promotes cancer cell growth and tumorigenicity
Ramirez-Moya, J.; Antika, T. R.; Liu, Q.; Xiong, X.; Ali, R.; Gutierrez, A.; Gregory, R. I.
10.1101/2024.10.31.621298 — cancer biology — Posted on 2024-11-03
4592 In Situ Single-Cell Spatial Profiling of Matrisome Gene Expression in Glioblastoma
De, A.; Forero, S. A.; Sebastian, S.; Morales, J. E.; De La Fuente-Granada, M.; Huse, J. T.; Ballester, L. Y.; Weinberg, J. S.; Lang, F. F.; Akdemir, K. C.; McCarty, J. H.
10.1101/2024.10.31.621280 — cancer biology — Posted on 2024-11-03
4594 Androgen receptor interactions provide insight into steroid mediated metabolic shifts in endocrine resistant breast cancer.
Bleach, R.; Bozkurt, E.; Sheehan, K.; Shirran, S.; Xin, J.; Agbana, S.; Ola, M.; Young, L.; O'Reilly, M. W.; Prehn, J. M.; McIlroy, M.
10.1101/2024.11.01.621520 — cancer biology — Posted on 2024-11-03
4596 Intrinsic bioenergetic adaptations compensate for reduced mitochondrial content in HER2-driven mammary tumors
Frangos, S. M.; Brunetta, H. S.; Wang, D.; Jabile, M. J. T.; Ma, D. W. L.; Muller, W.; Khursigara, C.; Fisher-Wellman, K. H.; Steinberg, G.; Holloway, G. P.
10.1101/2024.11.03.621754 — cancer biology — Posted on 2024-11-03
4598 Model-free photon analysis of diffusion-based single-molecule FRET experiments
Terterov, I.; Nettels, D.; Lasitza-Male, T.; Bartels, K.; Loew, C.; Vancraenenbroeck, R.; Carmel, I.; Rosenblum, G.; Hofmann, H.
10.1101/2024.10.31.621265 — biophysics — Posted on 2024-11-03
4600 Optical Interference for the Guidance of Cryogenic Focused Ion Beam Milling Beyond the Axial Diffraction Limit
Sica, A. V.; Zaoralova, M.; Antolini, C.; Daan, B. B.; Penzes, J. J.; Malmqvist, L. M.; Jensen, G. J.; Jason, K. T.; Dahlberg, P.
10.1101/2024.11.01.621231 — biophysics — Posted on 2024-11-03
4603 Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance
Muzata, D.; Sanyal, D.; Chivukula, A. S.; Upadhyay, P. D.; A, S.; Chakraborti, S.; Pandey, D.; Uversky, V. N.; Albers, M. W.; Zielinski, D. C.; Jasuja, R.; Chowdhury, S.
10.1101/2024.10.31.621387 — biophysics — Posted on 2024-11-03
4605 Proton selective conductance and gating of lysosomal cation channel TMEM175
Schulze, T.; Sprave, T.; Groebe, C.; Krumbach, J. H.; Behringer, M.; Hamacher, K.; Thiel, G.; Grimm, C.; Rauh, O.
10.1101/2024.11.01.621492 — biophysics — Posted on 2024-11-03
4606 Insight Into the Molecular Parameters of PEI Promoting an Efficient Gene Delivery into Cells
Montano Gonzalez, P. A.; Tranchimand, S.; Rochedy, M.; Leroyer, P.; Chapel, J.-P.; Chevance, S.; Schatz, C.; Gauffre, F.; Loyer, P.; Bravo Anaya, L. M.
10.1101/2024.11.01.621598 — biophysics — Posted on 2024-11-03
4608 BTS: scalable Bayesian Tissue Score for prioritizing GWAS variants and their functional contexts across omics data
Kuksa, P. P.; Ionita, M.; Carter, L. J.; Cifello, J.; Clark, K.; Valladares, O.; Leung, Y. Y.; Wang, L.-S.
10.1101/2024.10.30.621077 — bioinformatics — Posted on 2024-11-03
4609 CIWARS: a web server for waterborne antibiotic resistance surveillance using longitudinal metagenomic data
Emon, M. I.; Cheung, Y. F.; Stoll, J.; Rumi, M. A.; Brown, C.; Choi, J. M.; Moumi, N. A.; Ahmed, S.; Song, H.; Sein, J.; Yao, S.; Khan, A.; Gupta, S.; Kulkarni, R.; Butt, A.; Vikesland, P.; Pruden, A.; Zhang, L.
10.1101/2024.10.30.621203 — bioinformatics — Posted on 2024-11-03
4611 The combined use of scRNA-seq and network propagation highlights key features of pan-cancer Tumor-Infiltrating T cells
MANGELINCK, A.; MOLITOR, E.; MARCHIQ, I.; ALAOUI, L.; BOUAZIZ, M.; ANDRADE-PEREIRA, R.; DARVILLE, H.; BECHT, E.; LEFEBVRE, C.
10.1101/2024.10.31.621221 — bioinformatics — Posted on 2024-11-03
4614 High-accuracy prediction of 5-year progression-free melanoma survival using spatial proteomics and few-shot learning on primary tissue
Moeller, A.; Ostalecki, C.; Hartebrodt, A.; Breininger, K.; Erdmann, M.; Uderhardt, S.; Baur, A.; Blumenthal, D. B.
10.1101/2024.10.30.620850 — bioinformatics — Posted on 2024-11-03
4617 Differential Analysis of Alternative Splicing Events in gene regions using Residual Neural Networks
Ciccolella, S.; Denti, L.; Avila Cartes, J.; Della Vedova, G.; Pirola, Y.; Rizzi, R.; Bonizzoni, P.
10.1101/2024.10.30.621059 — bioinformatics — Posted on 2024-11-03
4618 SpaMTP: Integrative Statistical Analysis and Visualisation of Spatial Metabolomics and Transcriptomics data.
Causer, A.; Lu, T.; Fitzgerald, C.; Newman, A.; Vu, H.; Tan, X.; Vo, T. Q. A.; Cui, C.; Narayana, V. K.; Whittle, J. R.; Best, S. A.; Freytag, S.; Nguyen, Q.
10.1101/2024.10.31.621429 — bioinformatics — Posted on 2024-11-03
4622 Tokenized and Continuous Embedding Compressions of Protein Sequence and Structure
Lu, A. X.; Yan, W.; Yang, K. K.; Gligorijevic, V.; Cho, K.; Abbeel, P.; Bonneau, R.; Frey, N.
10.1101/2024.08.06.606920 — bioinformatics — Posted on 2024-11-03
4624 Limelight - An open, web-based tool for visualizing, sharing, and analyzing mass spectrometry data from DDA pipelines
Riffle, M.; Zelter, A.; Jaschob, D.; Hoopmann, M. R.; Faivre, D. A.; Moritz, R. L.; Davis, T. N.; MacCoss, M. J.; Isoherranen, N.
10.1101/2024.11.01.621597 — bioinformatics — Posted on 2024-11-03
4628 Accelerating Cell Culture Media Development Using Bayesian Optimization-Based Iterative Experimental Design
Narayanan, H.; Hinckley, J.; Barry, R.; Dang, B.; Wolffe, L. A.; Atari, A.; Tseng, Y.-Y.; Love, J. C.
10.1101/2024.10.29.620971 — bioengineering — Posted on 2024-11-03
4629 Multiplexed ultrasound imaging of gene expression
Nystrom, N. N.; Jin, Z.; Bennett, M. E.; Zhang, R.; Swift, M. B.; Shapiro, M. G.
10.1101/2024.10.30.621148 — bioengineering — Posted on 2024-11-03
4630 The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim
Hammond, C. V.; Williams, S. T.; Vega, M. M.; Ao, D.; Li, G.; Salati, R. M.; Pariser, K. M.; Shourijeh, M. S.; Habib, A. W.; Patten, C.; Fregly, B. J.
10.1101/2024.10.30.620965 — bioengineering — Posted on 2024-11-03
4631 A fast, muscle-actuated biohybrid swimming robot
Drennan, W. C.; Aydin, O.; Emon, B.; Li, Z.; JOY, M. S. H.; Barishman, A.; Kim, Y.; Wei, M.; Denham, D.; Carrillo, A.; Saif, M. T. A.
10.1101/2024.10.30.621139 — bioengineering — Posted on 2024-11-03
4633 Cytotoxicity and Characterization of 3D-Printable Resins Using a Low-Cost Printer for Muscle-based Biohybrid Devices
Liao, A. S.; Dai, K.; Irez, A. B.; Sun, A.; Bennington, M. J.; Schaffer, S.; Chopra, B.; Seok, J. M.; Adams, R.; Zhang, Y. J.; Webster-Wood, V. A.
10.1101/2024.10.31.621115 — bioengineering — Posted on 2024-11-03
4637 Low RT-based Genome Editing Fidelity in Mouse Hepatocytes: Challenges and Solutions
Dunyak, M. T.; Hanna, P.; Nan, A. X.; von Stetina, J.; Pokharel, R.; O'Hara, M.; Estes, B. J.; Zheng, K.; Svenson, S.; Andresen, J.; Li, W.; Agrawal, M.; Hughes, C.; Spicer, M.; Choudhary, V.; Kelley, L.; Wang, J.; Meagher, M.; Xie, J.; Mukherjee, S.; Finn, J. D.
10.1101/2024.10.31.621282 — bioengineering — Posted on 2024-11-03
4639 Reengineering mRNA lipid nanoparticles for systemic delivery to pancreas
Isaac, I.; Patel, L.; Tran, N.; Singam, A.; Guha, P.; Park, S.; Bhattacharya, C.
10.1101/2024.10.30.621163 — bioengineering — Posted on 2024-11-03
4640 Low-pressure Isochoric Freezing as a scalable technique for fresh food preservation
Maida, A.; Consiglio, T.; Bilbao, C.; Karman, A.; Takeoka, G.; Powell-Palm, M. J.; Rubinsky, B.
10.1101/2024.11.01.621432 — bioengineering — Posted on 2024-11-03
4644 Genomic epidemiology of emerging terbinafine-resistant Trichophyton indotineae
Rhodes, J.; Hui, C. S. T.; Delliere, S.; Summerbell, R.; Scott, J.; Kaur, A.; Barton, R.; Leitao, R.; Hemmings, S.; Goiriz, R.; Lambourne, J.; Farrer, R.; Schelenz, S.; Hay, R.; Borman, A.; Chowdhary, A.; Abdolrasouli, A.; Fisher, M.
10.1101/2024.10.29.620818 — genomics — Posted on 2024-11-03
4646 StableLift: Optimized Germline and Somatic Variant Detection Across Genome Builds
Wang, N. K.; Wiltsie, N.; Winata, H. K.; Fitz-Gibbon, S.; Gonzalez, A. E.; Zeltser, N.; Agrawal, R.; Oh, J.; Arbet, J.; Patel, Y.; Yamaguchi, T. N.; Boutros, P. C.
10.1101/2024.10.31.621401 — genomics — Posted on 2024-11-03
4647 JG2: an updated version of the Japanese population-specific reference genome
Sriwichaiin, S.; Makino, S.; Funayama, T.; Otsuki, A.; Kawashima, J.; Okamura, Y.; Tadaka, S.; the Tohoku Medical Megabank Project Study Group, ; Katsuoka, F.; Kumada, K.; Tsutsumi, S.; Kinoshita, K.; Yamamoto, M.; Tamiya, G.; Takayama, J.
10.1101/2024.11.01.621223 — genomics — Posted on 2024-11-03
4648 Lifespan in rodents with MYT1L heterozygous mutation
Schreiber, A.; Swift, R. G.; Wilson, L.; Kroll, K. L.; Dougherty, J. D.; Maloney, S. E.
10.1101/2024.10.30.621094 — genetics — Posted on 2024-11-03
4651 Synonymous codon usage defines functional gene families
Ghanegolmohammadi, F.; Ohnuki, S.; Byrne, S.; Begley, T.; Dedon, P.
10.1101/2024.10.31.621346 — genetics — Posted on 2024-11-03
4652 SNP panel for non-invasive genotyping of leopard (Panthera pardus)
Spong, G.; Bertola, L.; De Vry, A. M.; Dussex, N.; Shiffthaler, B.; Paijmans, J.; Hofreiter, M.; Forbes, R.; Kerley, G.; Everatt, K.; Becker, M.; Creel, S.; Bourgeois, S.; Drouilly, M.; Mamugy, F.
10.1101/2024.11.01.621452 — genetics — Posted on 2024-11-03
4662 Integrative analysis of CAM photosynthesis reveals its impact on primary metabolism in Yucca
Wickell, D. A.; Field, R.; Weitz, K.; Chu, R.; Trejo, J.; Tolic, N.; Munoz Munoz, N.; Hundley, H.; Savage, E.; Lipzen, A.; Leebens-Mack, J.; Heyduk, K.
10.1101/2024.11.01.621533 — evolutionary biology — Posted on 2024-11-03
4663 Holostean genomes reveal evolutionary novelty in the vertebrate immunoproteasome that have implications for MHCI function
Barker, A. V.; Carlson, K. B.; Wcisel, D. J.; Birchler De Allende, I.; Braasch, I.; Fisk, M.; Dornburg, A.; Yoder, J. A.
10.1101/2024.11.01.621518 — evolutionary biology — Posted on 2024-11-03
4669 Source amplitude increases with body mass across avian genera
Ziegenhorn, M. A.; Lanctot, R. B.; Brown, S. C.; Saalfeld, S. T.; Smith, P. A.; Lecomte, N.
10.1101/2024.10.31.621325 — ecology — Posted on 2024-11-03
4670 Quantifying the success of prey crypsis, aposematism and evasiveness in avoiding avian predators attack
Linke, D.; Mejia, J. H.; Navarro, V. N. P. E.; Gohil, P.; Garcia, C. R.; Salinas, L.; Elias, M.; Matos-Maravi, P.
10.1101/2024.10.31.621260 — ecology — Posted on 2024-11-03
4672 Enhancing cryopreservation of human iPSCs: Bottom-up vs Conventional freezing geometry
Teodoro, F.; El-Guendouz, S.; Neves, R.; Duarte, A.; Rodrigues, M. A.; Melo, E. P.
10.1101/2024.10.30.621091 — cell biology — Posted on 2024-11-03
4673 Multiomics reveals age-dependent metabolic reprogramming of macrophages by wound bed niche secreted signals
Forni, M. F.; Pizzurro, G. A.; Krause, W. S. W.; Alexander, A. F.; Bridges, K.; Xu, Y.; Justynski, O.; Gabry, A.; Camara, N. O. S.; Horsley, V.
10.1101/2024.10.30.621159 — cell biology — Posted on 2024-11-03
4676 H2S remodels mitochondrial ultrastructure and destabilizes respiratory supercomplexes
Hanna, D. A.; Chen, B.; Shah, Y. M.; Khalimonchuk, O.; Cunniff, B.; Banerjee, R.
10.1101/2024.10.30.621162 — cell biology — Posted on 2024-11-03
4677 Immunosuppression Drugs Exhibit Differential Effects on Endothelial Cell Function
Elezaby, A.; Dexheimer, R.; Wu, D.; Chan, S. Y.; Chen, I. Y.; Sayed, N.; Sallam, K.
10.1101/2024.10.31.620858 — cell biology — Posted on 2024-11-03
4679 High-throughput measurement of adipocyte size with open-source software using whole-slide adipose tissue images
Ramalho, A. C.; Gauthier, M.-F.; Maltais-Payette, I.; Ostinelli, G.; Hould, F.; Biertho, L.; Tchernof, A.
10.1101/2024.10.31.621327 — cell biology — Posted on 2024-11-03
4680 Identification of molecular and functional subtypes using chronic pancreatitis patient-derived organoid models
Osorio-Vasquez, V.; Lumibao, J. C.; Peck, K. L.; Lande, K.; Zhu, J.; Stamp, M.; Okhovat, S. R.; Song, H.; Ogawa, S.; Hsu, J.; Dai, Y.; Rock, A.; Bottomley, C.; Thomas, E.; McGriff, T.; Fowler, A.; Larsen, S.; Abdulla, M.; Gibson, J.; Greer, P.; Downes, M.; Evans, R.; Zou, J.; Lowy, A.; Whitcomb, D. C.; White, R.; Bellin, M.; Tiriac, H.; Engle, D. D.
10.1101/2024.10.30.620903 — cell biology — Posted on 2024-11-03
4681 Isotonic medium treatment limits burn wound microbial colonization and improves tissue repair
Horn, A.; Wagner, A. S.; Hou, Y.; Zajac, J. C.; Fister, A. M.; Chen, Z.; Pashaj, J.; Junak, M.; Soto, N. M. M.; Gibson, A.; Huttenlocher, A.
10.1101/2024.10.29.620892 — cell biology — Posted on 2024-11-03
4682 Expression Profile of Human Bitter Taste Receptors in Human Aortic and Coronary Artery Endothelial Cells
Kochany, P.; Opiełka, M.; Słonimska, P.; Gulczynski, J.; Kostrzewa, T.; Łos, A.; Znaniecki, Łukasz; Mickiewicz, A.; Izycka-Swieszewska, E.; Sachadyn, P.; Wozniak, M.; Gruchała, M.; Gorska-Ponikowska, M.
10.1101/2024.10.31.621361 — cell biology — Posted on 2024-11-03
4683 Microtubule plus-end dynamics are tightly coupled to the turnover of the MOR1 polymerase
Eng, R. C.; Halat, L. S.; Kuo, C.-C.; Rakei, A.; Costain, C.; Diehl, K. A.; Blutrich, R.; Lechner, B.; Zhang, Y.; Walia, A.; Alonso, J. M.; Coombs, D.; Wasteneys, G. O.
10.1101/2024.10.30.621176 — cell biology — Posted on 2024-11-03
4684 The proteomic landscape of proteotoxic stress in a fibrogenic liver disease
Rosenberger, F. A.; Maedler, S. C.; Holtz Thorhauge, K.; Steigerwald, S.; Fromme, M.; Lebedev, M.; Weiss, C. A. M.; Oeller, M.; Wahle, M.; Zwiebel, M.; Schmacke, N. A.; Detlefsen, S.; Boor, P.; Kaserman, J.; Wilson, A. A.; Fabian, O.; Frankova, S.; Krag, A.; Strnad, P.; Mann, M.
10.1101/2024.11.01.621457 — cell biology — Posted on 2024-11-03
4688 Unveiling a unique macrophage population in exocrine glands sustained by ILC2-derived GM-CSF
Westermann, F.; Tuzlak, S.; Kreiner, V.; Bejarano, D.; Bijnen, M.; Cecconi, V.; van Hove, H.; Wang, H.; Litscher, G.; Ignacio, A.; Lindemann, R.; Oberbichler, L.; DeFeo, D.; Liu, Z.; Kipar, A.; MyCoy, K.; Nixon, I.; Bain, C. C.; Schneider, C.; Tugues, S.; Greter, M.; Ginhoux, F.; Schlitzer, A.; Emmerson, E.; Becher, B.
10.1101/2024.10.30.620897 — immunology — Posted on 2024-11-03
4691 Basement membrane hydrogels dampen CAR-T cell activation: nanofibrillar cellulose gels as alternative to preserve T cell function in 3D cell cultures.
Revilla, S. A.; Cutilli, A.; Rockx-Brouwer, D.; Frederiks, C. L.; Falandt, M.; Levato, R.; Kranenburg, O.; Lindemans, C.; Coffer, P.; Peperzak, V.; Mocholi-Gimeno, E.; Cuenca, M.
10.1101/2024.10.29.620948 — immunology — Posted on 2024-11-03
4692 Single-cell multiomics of pediatric BM reveals age-dependent differences in lineage differentiation linked to stromal cell heterogeneity
Hanemaaijer, E. S.; Muskens, K. F.; Kal, I. J.; te Pas, B. M.; Fryzik, P.; Epskamp, N.; Balwierz, A.; Candelli, T.; de Jonge, W. J.; Margaritis, T.; Belderbos, M. E.
10.1101/2024.10.31.621155 — immunology — Posted on 2024-11-03
4693 The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes
Wang, J. E.; Muralidharan, C.; Nargis, T.; Enriquez, J. R.; Anderson, R. M.; Mirmira, R. G.; Tersey, S. A.
10.1101/2024.10.31.621343 — immunology — Posted on 2024-11-03
4695 Loss of KDM6A-mediated genomic instability and metabolic reprogramming differentially regulates responses to immune checkpoint therapy and chemotherapy in bladder cancer.
Singh, P.; Raychaudhuri, D.; Chakraborty, B.; Meher, S.; Tannir, A. J.; Majumdar, A.; Hawkins, J.; Xiong, Y.; Lorenzi, P.; Sharma, P.; Pilie, P.; Goswami, S.
10.1101/2024.10.31.621396 — immunology — Posted on 2024-11-03
4696 Rapamycin Enhances CAR-T Control of HIV Replication and Reservoir Elimination in vivo.
Zhen, A.; Mu, W.; Tomer, S.; Harding, J.; Kedia, N.; Cook, E.; Patankar, V.; Carrillo, M.; Martin, H.; Ng, H.; Wang, L.; Marsden, M.; Kitchen, S.
10.1101/2024.10.31.621350 — immunology — Posted on 2024-11-03
4697 The C3-C3aR axis modulates trained immunity in alveolar macrophages
Earhart, A. P.; Alburquerque, R. A.; Starick, M.; Nallapu, A.; Garnica, L.; Ozanturk, A. N.; Maurya, R. K.; Wu, X.; Haspel, J. A.; Kulkarni, H. S.
10.1101/2024.11.01.621042 — immunology — Posted on 2024-11-03
4699 MethylGPT: a foundation model for the DNA methylome
Ying, K.; Song, J.; Cui, H.; Zhang, Y.; Li, S.; Chen, X.; Liu, H.; Eames, A.; McCartney, D. L.; Marioni, R. E.; Poganik, J. R.; Moqri, M.; Wang, B.; Gladyshev, V. N.
10.1101/2024.10.30.621013 — systems biology — Posted on 2024-11-03
4702 Genomic Architecture of the Resistance to Phytophthora Cactorum 2 (RPc2) Locus in Strawberry (Fragaria x ananassa)
Han, H.; Oh, Y.; Jang, Y. J.; Chandra, S.; Gill, U.; Verma, S.; Noh, Y.-H.; Isobe, S.; Pincot, D. D. A.; cole, G. S.; Famula, R.; Feldmann, M. J.; Knapp, S. J.; Whitaker, V.; Lee, S.
10.1101/2024.11.01.621609 — plant biology — Posted on 2024-11-03
4703 Gene Therapy with the N-terminal Fragment of Nav1.5 for Cardiac Channelopathies: A Novel Transcomplementation Mechanism Potentiating the Cardiac Sodium Current
Gizon, M.; FERRAND, M. C.; Fontaine, V.; Mougenot, N.; Laporte, P.-L.; Gaborit, N.; Extramiana, F.; Baro, I.; Guicheney, P.; Charpentier, F.; Doisne, N.; Neyroud, N.
10.1101/2024.10.30.621028 — physiology — Posted on 2024-11-03
4708 Fertility Preservation of Vacuum-Dried Ram Spermatozoa Stored for Four Years at Room Temperature
Moncada, M.; Lo Sterzo, M.; Palazzese, L.; Boffa, F.; Anzalone, D. A.; Iuso, D.; Czernik, M.; Gioia, L.; Turri, F.; Mislei, B.; Bucci, D.; Bonnet, J.; Colotte, M.; Tuffet, S.; Bochenek, M.; Loi, P.
10.1101/2024.10.31.621253 — physiology — Posted on 2024-11-03
4710 ATGL-mediated lipolysis is essential for myocellular mitochondrial function and augments PPARδ-induced improvements in mitochondrial respiration
Gemmink, A.; van de Weijer, T.; Schaart, G.; Grabner, G. F.; Kornips, E.; Knoops, K.; Zechner, R.; Schweiger, M.; Hesselink, M. K. C.
10.1101/2024.10.31.621255 — physiology — Posted on 2024-11-03
4712 Environmentally Relevant Lead Exposure Impacts Gene Expression in SH-SY5Y Cells Throughout Neuronal Differentiation
Morgan, R. K.; Tapaswi, A.; Polemi, K. M.; Tolrud, E. C.; Bakulski, K. M.; Svoboda, L. K.; Dolinoy, D. C.; Colacino, J. A.
10.1101/2024.10.29.620844 — pharmacology and toxicology — Posted on 2024-11-03
4713 Discovery and isolation of novel capsaicinoids and their TRPV1-related activity
Smith, J.; Stillerov, V. T.; Dracinsky, M.; Gaustad, H. L. A.; Lorenzi, Q.; Smrckova, H.; Reinardt, J. K.; Lienard, M. A.; Bednarova, L.; Sacha, P.; Pluskal, T.
10.1101/2024.10.29.620944 — pharmacology and toxicology — Posted on 2024-11-03
4717 Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model
Bonatti, M.; Pitozzi, V.; Caruso, P.; Pontis, S.; Pittelli, M. G.; Frati, C.; Madeddu, D.; Quaini, F.; Lagrasta, C. A. M.; Minato, I.; Bocchi, E.; Civelli, M.; Villetti, G.; Trevisani, M.; Montanini, B.
10.1101/2024.10.30.620876 — pharmacology and toxicology — Posted on 2024-11-03
4718 Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease
Carles, A.; Freyssin, A.; Guehairia, S.; Reguero, T.; Vignes, M.; Hirbec, H. E.; Rubinstenn, G.; Maurice, T.
10.1101/2024.10.31.621224 — pharmacology and toxicology — Posted on 2024-11-03
4722 Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue
Kubik, S.; Matyszczak, I.; Toda, N.; Magrinelli, E.; Helleboid, P.-Y.; Smith, E.; Bezrukov, F.; Ryder, C.; Lopez, J.; Harle, A.; Xu, Z.
10.1101/2024.10.30.621018 — cancer biology — Posted on 2024-11-03
4723 A novel in-vitro model of the bone marrow microenvironment in AML identifies CD44 and Focal Adhesion Kinase as therapeutic targets to reverse cell adhesion-mediated drug resistance
Ladikou, E. E.; Sharp, K.; Simoes, F. A.; Jones, J.; Burley, T.; Stott, L.; Vareli, A.; Kennedy, E. M.; Chevassut, T. J.; Devi, A.; Ashworth, I.; Ross, D.; Hartmann, T.; Mitchell, S.; Pepper, C.; Best, G.; Pepper, A.
10.1101/2024.10.30.621120 — cancer biology — Posted on 2024-11-03
4726 Counterfactual Diffusion Models for Mechanistic Explainability of Artificial Intelligence Models in Pathology
Zigutyte, L.; Lenz, T.; Han, T.; Hewitt, K. J.; Reitsam, N. G.; Foersch, S.; Carrero, Z.; Unger, M.; Pearson, A. T.; Truhn, D.; Kather, J. N.
10.1101/2024.10.29.620913 — bioinformatics — Posted on 2024-11-03
4727 cOmicsArt - a customizable Omics Analysis and reporting tool
Seep, L.; Jost, P. J.; Lisowski, C.; Huang, H.; Grein, S.; Mass, E.; Kurts, C.; Hasenauer, J.
10.1101/2024.10.30.621025 — bioinformatics — Posted on 2024-11-03
4728 Inflammatory molecules in the glomerular endothelium in mild IgA-Nephropathy identified by single-cell and spatial transcriptome
Hasegawa, K.; Kawashima, N.; Kawabata, A.; Sakakura, M.; Onoda, N.; Sano, T.; Urakawa, I.; Matsubara, M.; NAITO, S.
10.1101/2024.10.30.621002 — bioinformatics — Posted on 2024-11-03
4732 Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells
Jones, R. D.; Salim, K.; Stankiewicz, L. N.; Edgar, J. M.; Leon, L.; Gillies, J. K.; Murtaza, A.; Durland, L. J.; Raval, D.; Taberna, T. P.; Hsu, H. H.; Zimmerman, C.; Michales, Y. S.; Rossi, F. M. V.; Levings, M. K.; Zandstra, P. W.
10.1101/2024.10.29.620998 — bioengineering — Posted on 2024-11-03
4733 BLOC: buildable and linkable organ on a chip
Kimura, Y.; Hamaguchi, H.; Oyama, K.; Oyama, T. G.; Kimura, A.; Ohshima, Y.; Ishioka, N. S.; Taguchi, M.
10.1101/2024.10.29.620775 — bioengineering — Posted on 2024-11-03
4735 A polyketide-based biosynthetic platform for diols, amino alcohols and hydroxyacids
Dan, Q.; Chiu, Y.; Lee, N.; Pereira, J. H.; Zhao, X.; Zhan, C.; Rong, Y.; Chen, Y.; Cheong, S.; Li, C.; Gin, J. W.; Rodrigues, A.; Backman, T. W. H.; Baidoo, E. E. K.; Petzold, C. J.; Adams, P. D.; Keasling, J. D.
10.1101/2024.10.29.620908 — bioengineering — Posted on 2024-11-03
4737 To nest or not to nest: environmental cues for olive ridley mass nesting events in Odisha, India
Srikanthan, P.; Pusapati, C.; Verma, A.; Dhal, G.; Manoharakrishnan, M.; Shanker, K.
10.1101/2024.10.29.620945 — ecology — Posted on 2024-11-03
4738 Golden eagles regularly use gravity waves to soar in the Alps: new insights from high-resolution weather data
Carrard, T.; Nourani, E.; Jansing, L.; Zimmermann, T.; Sumasgutner, P.; Tschumi, M.; Jenny, D.; Wikelski, M.; Safi, K.; Sprenger, M.; Scacco, M.
10.1101/2024.10.29.620992 — ecology — Posted on 2024-11-03
4743 TACSTD2 expression marks the early transition to colon adenomas
Siskova, A.; Huebner, K.; Ferrero, G.; Gehring, A.; Hampel, C.; Naccarati, A.; Pardini, B.; Tarallo, S.; Geppert, C. I.; Prochazka, J.; Tureckova, J.; Jungwirth, J.; Hucl, T.; Kral, J.; Vodickova, L.; Erlenbach-Wuensch, K.; Hartmann, A.; Honkova, K.; Matej, R.; Vodicka, P.; Vymetalkova, V.; Schneider-Stock, R.
10.1101/2024.10.29.620817 — cancer biology — Posted on 2024-11-03
4744 Spatial Transcriptomics of IPMN Reveals Divergent Indolent and Malignant Lineages
Iyer, M. K.; Fletcher, A.; Shi, C.; Chen, F.; Kanu, E.; Eckhoff, A.; Bao, M.; Frankel, T. L.; Chinnaiyan, A. M.; Nussbaum, D. P.; Allen, P. J.
10.1101/2024.10.29.620810 — cancer biology — Posted on 2024-11-03
4746 Predicting Mouse Lifespan-Extending Chemical Compounds with Machine Learning
Belikov, A. V.; Ribeiro, C.; Farmer, C. K.; de Magalhaes, J. P.; Freitas, A. A.
10.1101/2024.10.29.620854 — bioinformatics — Posted on 2024-11-03
4749 Target-specific design of drug-like PPI inhibitors via hot-spot-guided generative deep learning
Sun, H.; Li, J.; Zhang, Y.; Lin, S.; Chen, J.; Tan, H.; Wang, R.; Mao, X.; Zhao, J.; Li, R.; Xiong, Y.; Wei, D.-Q.
10.1101/2024.10.29.620869 — bioinformatics — Posted on 2024-11-03
4752 Bacterial Engineered Living Materials modulate Mechanosignaling in Mammalian Cells
Ostmann, K.; Munoz-Guamuro, G.; Becker, J.; Banos, M.; Saikumar, S.; Bennewitz, R.; Duong, C. N.; Sankaran, S.; Weber, W.
10.1101/2024.10.29.620857 — bioengineering — Posted on 2024-11-03
4754 Extending the Coding-variant Allelic Series Test to Summary Statistics
McCaw, Z. R.; Gao, J.; Dey, R.; insitro Research Team, ; Fox, E.; O'Dushlaine, C.; Soare, T. W.
10.1101/2024.10.31.621375 — genetics — Posted on 2024-11-03
4755 PRECISE EXOME ANALYSIS OF BLASTOCYST BIOPSY SCALE SAMPLES USING PRIMARY TEMPLATE-DIRECTED AMPLIFICATION
Samitova, A.; Belova, V.; Vasiliadis, I.; Repinskaia, Z.; Gorodnicheva, T.; Romanov, E.; Pogosyan, M.; Gaysin, E.; Nazarenko, T.; Rebrikov, D.; Korostin, D.
10.1101/2024.10.29.620888 — genetics — Posted on 2024-11-03
4756 FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments
Kuthethur, R.; Acharya, A.; Sengodan, S. K.; Fonseca, C.; Nagar, N.; Nasrin VZ, S.; Ibini, O.; Manolika, E.-M.; de Koning, K.; Braunshier, S.; Dessapt, J.; Fradet-Turcotte, A.; Lebbink, J. H. G.; Kanaar, R.; Poluri, K. M.; Sharan, S. K.; Cejka, P.; Chaudhuri, A. R.
10.1101/2024.11.03.621741 — genetics — Posted on 2024-11-03
4761 Discovery of a multipotent cell type from the term human placenta
Vadakke-Madathil, S.; Bouhamida, E.; Wang, B.; Mathiyalagan, P.; Oniskey, M.; Santos-Gallego, C.; Hadley, M.; Croft, L.; Dekio, F.; Brody, R.; Gelber, S.; Sperling, R.; Chaudhry, H. W.
10.1101/2023.08.02.551028 — cell biology — Posted on 2024-11-03
4762 Chronic stress antagonizes formation of Stress Granules
Adachi, Y.; Williams, A.; Masuda, M.; Taketani, Y.; Anderson, P.; Ivanov, P.
10.1101/2024.10.29.620814 — cell biology — Posted on 2024-11-03
4763 The Accumulation of Progerin Underlies the Loss of Aortic Smooth Muscle Cells in Hutchinson-Gilford Progeria Syndrome
Kim, P. H.; Kim, J. R.; Heizer, P. J.; Jung, H.; Tu, Y.; Presnell, A.; Scheithauer, J.; Yu, R. G.; Young, S. G.; Fong, L. G.
10.1101/2024.10.29.620896 — cell biology — Posted on 2024-11-03
4764 Methylglyoxal is an antibacterial effector produced by macrophages during infection
Anaya-Sanchez, A.; Berry, S. B.; Espich, S.; Zilinskas, A.; Tran, P. M.; Agudelo, C.; Samani, H.; Darwin, K. H.; Portnoy, D. A.; Stanley, S.
10.1101/2024.11.03.621721 — microbiology — Posted on 2024-11-03
4765 Assessing the Biosecurity Risk of Footwear as a Fomite for Transmission of Adventitious Infectious Agents to Mice
Palillo, M. B.; Mishkin, N.; Atmane, M.; Palillo, J. A.; Carrasco, S.; Woods, C.; Henderson, K.; Lipman, N. S.; Arbona, R. R.
10.1101/2024.11.03.621730 — microbiology — Posted on 2024-11-03
4768 Synchronous activation of striatal cholinergic interneurons induces local serotonin release
Matityahu, L.; Hobel, Z.; Berkowitz, N.; Malady, J. M.; Gilin, N.; Plotkin, J. L.; Goldberg, J. A.
10.1101/2024.11.03.621726 — neuroscience — Posted on 2024-11-03
4770 Phase Separation to Resolve Growth-Related Circuit Failures
Zhang, R.; Yang, W.; Zhang, R.; Rijal, S.; Youssef, A.; Zheng, W.; Tian, X.
10.1101/2024.11.01.621586 — synthetic biology — Posted on 2024-11-03
4771 Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays
Shrestha, S.; Acharya, P.; Kang, S.-Y.; Vanga, M. G.; Lekkala, V. K. R.; Liu, J.; Yang, Y.; Joshi, P.; Lee, M.-Y.
10.1101/2024.03.25.586638 — bioengineering — Posted on 2024-11-03
4775 Pyramidal cell types and 5-HT2A receptors are essential for psilocybin's lasting drug action
Shao, L.-X.; Liao, C.; Davoudian, P. A.; Savalia, N. K.; Jiang, Q.; Wojtasiewicz, C.; Tan, D.; Nothnagel, J. D.; Liu, R.-J.; Woodburn, S. C.; Bilash, O. M.; Kim, H.; Che, A.; Kwan, A. C.
10.1101/2024.11.02.621692 — neuroscience — Posted on 2024-11-03
4776 Cilia dysfunction in the lateral ventricles after neonatal intraventricular hemorrhage does not lead to functional changes in cilia-based CSF flow networks
Pan, S.; Ramagiri, S.; Yang, L.; Giles, D. A.; Xu, I.; Garcia Bonilla, M.; DeFreitas, D.; Siderowf, L. W.; Koneru, S.; Halupnik, G. L.; Koller, G. M.; Polavarapu, S.; Gupta, D. K.; Miller, M. J.; Esakky, P.; Limbrick, D. D.; Bayly, P. V.; Horani, A.; Brody, S. L.; Mahjoub, M. R.; Strahle, J.
10.1101/2024.11.03.621724 — neuroscience — Posted on 2024-11-03
4778 Neuron-astrocyte Coupling in Lateral Habenula Mediates Depressive-like Behaviors
Xin, Q.; Wang, J.; Zheng, J.; Tan, Y.; Jia, X.; Ni, Z.; Feng, J.; Wu, Z.; Li, Y.; Li, X.; Ma, H.; Hu, H.
10.1101/2024.11.03.621722 — neuroscience — Posted on 2024-11-03
4785 Sleep Disruption Improves Performance in Simple Olfactory and Visual Decision-Making Tasks
Pflitsch, P.; Oury, N.; Krishnan, K.; Joo, W.; Lyons, D. G.; Capelle, M.; Herrera, K. J.; Bahl, A.; Rihel, J.; Engert, F.; Zwaka, H.
10.1101/2024.11.02.621641 — neuroscience — Posted on 2024-11-03
4786 Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study
Cupo, L.; Vecchiarelli, H. A.; Gallino, D.; VanderZwaag, J.; Bradshaw, K.; Phan, A.; Khakpour, M.; Ben-Azu, B.; Guma, E.; Fouquet, J.; Spring, S.; Nieman, B.; Devenyi, G. A.; Tremblay, M.-E. A.; Chakravarty, M.
10.1101/2024.11.02.621669 — neuroscience — Posted on 2024-11-03
4787 Constitutive expression of CX3CR1-BAC-Cre introduces minimal off-target effects in microglia
Mroue-Ruiz, F. H.; Desai, B.; Garvin, M.; Shehu, J.; Kamau, F.; Kar, U.; Bolton, J. L.
10.1101/2024.11.01.621625 — neuroscience — Posted on 2024-11-03
4793 Isoprene deters insect herbivory by priming plant hormone responses
Sahu, A.; Mostofa, M. G.; Xu, Y.; Serda, B.; O'Keefe, J.; Sharkey, T. D.
10.1101/2024.11.01.621578 — plant biology — Posted on 2024-11-03
4795 The mechanism of checkpoint-dependent DNA replication fork stabilization in human cells
Bertolin, A. P.; Canal, B.; Yekezare, M.; Zeng, J.; Instrell, R.; Howell, M.; Diffley, J. F. X.
10.1101/2024.11.01.621514 — cell biology — Posted on 2024-11-03
4797 Intestinal stem cells enhance local mucosal immunity through apoptotic body phagocytosis
Zhou, J. Y.; Lu, Q.; Hu, Y.; Fujji, S.; Espenschied, S. T.; Engelhart, M. J.; Lewis, K. J.; Karell, P. E.; Han, Y. T.; Shin, H.; Schmidt, R. E.; Silver, D. J.; Ivanov, A.; Yilmaz, O. H.; Stappenbeck, T.
10.1101/2024.10.29.620856 — cell biology — Posted on 2024-11-03
4798 The nephronophthisis protein GLIS2/NPHP7 is required for the DNA damage response in kidney tubular epithelial cells
Ebert, L. K.; Schloesser, L.; Frech, L.; Jain, M.; Dafinger, C.; Liebau, M. C.; Benzing, T.; Schermer, B.; Slaats, G. G.
10.1101/2024.11.02.621644 — cell biology — Posted on 2024-11-03
4799 Genomic Architecture of the Resistance to Phytophthora Cactorum 2 (RPc2) Locus in Strawberry (Fragaria x ananassa)
Han, H.; Oh, Y.; Jang, Y. j.; Chandra, S.; Gill, U.; Verma, S.; Noh, Y.-H.; Isobe, S.; Pincot, D. D. A.; cole, G. S.; Famula, R.; Feldmann, M. J.; Knapp, S. J.; Whitaker, V.; Lee, S.
10.1101/2024.11.01.621609 — plant biology — Posted on 2024-11-03
4800 A Novel Cisplatin-Based Prodrug Inhibits Lysine Deacetylases, Suppresses Nucleotide Excision Repair, and Overcomes Resistance
Negev Korem, Y.; Stern, E.; Golan-Berman, H.; Heilbrun, E. E.; Karmakar, S.; Soroka, Y.; Frusic-Zlotkin, M.; Chen, O.; Hassanain, H.; Wald, O.; Gibson, D.; Kohen, R.; Adar, S.
10.1101/2024.10.30.621050 — molecular biology — Posted on 2024-11-03
4801 Positive impact of Type-A and -C response regulator genes on growth and panicle architecture in rice
Rong, C.; Zhang, R.; Xie, J.; Li, J.; Yan, T.; Liu, Z.; Liu, Y.; Xu, R.; Shi, X.; Zhao, X.; Song, J.; Meng, Y.; Chang, Z.; Ding, Y.; Ding, C.
10.1101/2024.10.28.620749 — plant biology — Posted on 2024-11-03
4802 Many transcription factor families have evolutionarily conserved binding motifs in plants
Zenker, S.; Wulf, D.; Meierhenrich, A.; Viehöver, P.; Becker, S.; Eisenhut, M.; Stracke, R.; Weisshaar, B.; Bräutigam, A.
10.1101/2024.10.31.621407 — plant biology — Posted on 2024-11-03
4805 Platelets are Protective in Early Abdominal Aortic Aneurysm Formation
Russell, H. M.; Spuzzillo, A.; Benson, T. W.; Jaworski, J.; Clement, M.; Boulaftali, Y.; Saum, K.; Conrad, K. A.; Howatt, D. A.; Luyendyk, J. P.; Cameron, S. J.; Nieswandt, B.; Steinhubl, S. R.; Daugherty, A.; Bergmeier, W.; Tong, W.; Damrauer, S.; Tsao, P.; Mallat, Z.; Edwards, T. L.; Mackman, N.; Owens, A. P.
10.1101/2024.10.29.616205 — pathology — Posted on 2024-11-03
4806 The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds
Mannochio-Russo, H.; Charron-Lamoureux, V.; van Faassen, M.; Lamichhane, S.; Goncalves Nunes, W. D.; Deleray, V.; Patan, A.; Vittali, K.; Rajkumar, P.; El Abiead, Y.; Zhao, H. N.; Portal Gomes, P. W.; Mohanty, I.; Lee, C.; Sund, A.; Sharma, M.; Liu, Y.; Pattynama, D.; Walker, G. T.; Norton, G. J.; Khatib, L.; Andalibi, M. S.; Wang, C. X.; Ellis, R. J.; Moore, D. J.; Iudicello, J. E.; Franklin, D.; Letendre, S.; Chin, L.; Walker, C.; Renwick, S.; Zemlin, J.; Meehan, M. J.; Song, X.; Kasper, D.; Burcham, Z.; Kim, J. J.; Kadakia, S.; Raffatellu, M.; Bode, L.; Zengler, K.; Wang, M.; Siegel, D.; Kn
10.1101/2024.10.31.621412 — bioinformatics — Posted on 2024-11-03
4807 Development of an ELISA assay for EV quantification to assist the large-scale EV manufacture
Zhou, X.; Wang, W.; Zhang, L.; Yang, S.; Peng, X.; Zhang, X.; Zhao, J.; Xu, K.; He, X.
10.1101/2024.10.31.621446 — biochemistry — Posted on 2024-11-03
4808 The spliceosomal component GAMETOPHYTIC FACTOR 1 (GFA1) regulates a key photoperiodic switch
Tiedemann, S.; Sterck, L.; Becker, H.; Nielsen, N.; Blohm, C.; Blum, D.; Lanz, C.; Maedler, K.; Weigel, D.; Van de Peer, Y.; Gross-Hardt, R.
10.1101/2024.11.01.621476 — developmental biology — Posted on 2024-11-03
4809 Dissociation of the nuclear basket triggers chromosome loss in aging yeast
Mirkovic, M.; McCarthy, J.; Meinema, A. C.; Partenau, J.; Lee, S. S.; Elela, S. A.; Barral, Y.
10.1101/2024.10.31.621394 — cell biology — Posted on 2024-11-03
4811 Evolutionarily diverse caveolins share a common structural framework built around amphipathic discs
Han, B.; Connolly, S.; Wilson, L. F. L.; Schultz, D. T.; Gulsevin, A.; Meiler, J.; Karakas, E.; Ohi, M. D.; Kenworthy, A. K.
10.1101/2022.11.15.516482 — biophysics — Posted on 2024-11-03
4813 Tethering ferredoxin-NADP+ reductase to photosystem I promotes photosynthetic cyclic electron transfer
Emrich-Mills, T. Z.; Proctor, M. S.; Degen, G. E.; Jackson, P. J.; Richardson, K.; Hawkings, F.; Buchert, F.; Hitchcock, A.; Hunter, N.; Mackinder, L.; Hippler, M.; Johnson, M. P.
10.1101/2024.11.01.621516 — biochemistry — Posted on 2024-11-03
4817 The Kinetochore Protein KNL-1 Regulates the Actin Cytoskeleton to Control Dendrite Branching
Domingos, H. A.; Green, M.; Ouzounidis, V. R.; Finlayson, C.; Prevo, B.; Cheerambathur, D. K.
10.1101/2023.03.29.534821 — cell biology — Posted on 2024-11-03
4821 PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
Sherman, D. J.; Liu, L.; LaGory, E. L.; Fordstrom, P.; Pruitt, D.; Barreda, J.; Xie, J.; Ferbas, J.; Rulifson, I. C.; Deshaies, R. J.
10.1101/2024.10.29.620978 — cell biology — Posted on 2024-11-03
4822 Vinculin Y822 phosphorylation regulates cardiomyocyte adhesion dynamics and adherens junction maturation in the heart
Li, X.; Wortelboer, R.; Song, Y.; Balasubramanian, S.; McLain, C.; Hernandez Manriquez, A.; Suh, J.; Hoffman, B. D.; Kwiatkowski, A. V.; Radice, G. L.
10.1101/2024.10.28.620745 — cell biology — Posted on 2024-11-03
4823 Dominant-negative TP53 mutations potentiated by the HSF1-regulatedproteostasis network
Sebastian, R. M.; Patrick, J. E.; Hui, T.; Amici, D. R.; Giacomelli, A. O.; Butty, V. L.; Hahn, W. C.; Mendillo, M. L.; Lin, Y.-S.; Shoulders, M. D.
10.1101/2024.11.01.621414 — molecular biology — Posted on 2024-11-03
4824 Pre-rRNA spatial distribution and functional organization of the nucleolus
Pan, Y.-H.; Shan, L.; Yang, Z.-H.; Zhang, Y.-Y.; Zhang, Y.; Cao, S.-M.; Zhang, J.; Yang, L.; Chen, L.-L.
10.1101/2024.11.02.621631 — molecular biology — Posted on 2024-11-03
4825 Metabolic regulation of RNA methylation by the m6A-reader IGF2BP3
Sharma, G.; Gutierrez, M.; Jones, A. E.; Jaiswal, A. K.; Neeb, Z. T.; Rios, A.; Thaxton, M. L.; Lin, T. L.; Tran, T. M.; Kabbani, L. E. S.; Ritter, A. J.; Stiles, L.; ten Hoeve, J.; Divakaruni, A. S.; Sanford, J. R.; Rao, D. S.
10.1101/2024.10.31.621399 — cancer biology — Posted on 2024-11-03
4826 An Open Competition for Biomarkers of Aging
Ying, K.; Paulson, S.; Reinhard, J.; Camillo, L. P. d. L.; Trauble, J.; Jokiel, S.; Biomarkers of Aging Consortium, ; Gobel, D.; Herzog, C.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.
10.1101/2024.10.29.620782 — bioinformatics — Posted on 2024-11-03
4828 Site-specific DNA insertion into the human genome with engineered recombinases
Fanton, A.; Bartie, L. J.; Martins, J. Q.; Tran, V. Q.; Goudy, L.; Durrant, M. G.; Wei, J.; Pawluk, A.; Konermann, S.; Marson, A.; Gilbert, L. A.; Hsu, P. D.
10.1101/2024.11.01.621560 — bioengineering — Posted on 2024-11-03
4833 Single-cell atlas of developing mouse palates reveals cellular and molecular transitions in periderm cell fate
Huang, W.; Qian, Z.; Zhang, J.; Ding, Y.; Wang, B.; Lin, J.; Zhang, X.; Zhao, H.; Chen, F.
10.1101/2024.10.28.620753 — genomics — Posted on 2024-11-03
4835 CELF2 promotes tau exon 10 inclusion via hinge domain-mediated nuclear condensation
Li, X.; Syed, I.; Zhang, Z.; Adhikari, R.; Tang, D.; Ko, S.-H.; Liu, Z.; Chen, L.
10.1101/2024.11.02.621395 — molecular biology — Posted on 2024-11-03
4837 Radular teeth matrix protein 1 directs iron oxide deposition in chiton teeth
Nemoto, M.; Okada, K.; Akamine, H.; Odagaki, Y.; Narahara, Y.; Okoshi, K.; Obuse, K.; Kisailus, D.; Moriya, H.; Satoh, A.
10.1101/2024.11.02.621658 — molecular biology — Posted on 2024-11-03
4838 A high-throughput protein tagging toolkit that retains endogenous UTRs for studying gene regulation in Kinetoplastids.
Carbajo, C. G.; Han, X.; Savur, B.; Upadhyaya, A.; Taha, F.; Tinti, M.; Wheeler, R. J.; Yates, P. A.; Tiengwe, C.
10.1101/2024.11.02.621556 — molecular biology — Posted on 2024-11-03
4839 SloR-SRE binding to the S. mutans mntH promoter is cooperative.
Ziogas, M.; Drummond, I. Y.; Todorovic, I.; Kraczkowsky, K. N.; Zhang, H.; Wu, H.; Spatafora, G.
10.1101/2024.11.02.621577 — microbiology — Posted on 2024-11-03
4841 Self-Authenticating Genomic Materials with Advanced Genome Signatures
Wang, Z.; Cui, J.; Liu, Q.; Li, J.; Guo, C.; Liu, Y.; Jiang, C.; Xue, H.; Li, J.; Ke, Y.; Qi, H.
10.1101/2024.11.02.621633 — synthetic biology — Posted on 2024-11-03
4842 RvD1 and LXA4 inhibitory effects on cardiac voltage-gated potassium channels
de la Cruz, A.; Ronchi, C.; Bartolucci, C.; Socuellamos, P. G.; de Benito-Bueno, A.; Severi, S.; Zaza, A.; Valenzuela, C.
10.1101/2024.10.29.620806 — pharmacology and toxicology — Posted on 2024-11-03
4845 Deep generative model for protein subcellular localization prediction
Yang, L.; Yuan, G.-H.; Li, J.; Yang, Z.; Chen, Y.-Q.; Yuan, Z.; Chen, T.; Ouyang, W.; Dong, N.
10.1101/2024.10.29.620765 — bioinformatics — Posted on 2024-11-03
4846 Antigen-specific T cell immunotherapy by in vivo mRNA delivery
Su, F.-Y.; Siebart, J. C.; Chan, C. S.; Wang, M. Y.; Yao, X.; Trenkle, A. D. S.; Sivakumar, A.; Su, M.; Harandi, R.; Shahrawat, N.; Nguyen, C. H.; Goenka, A.; Mun, J.; Dhodapkar, M. V.; Kwong, G. A.
10.1101/2024.10.29.620946 — bioengineering — Posted on 2024-11-03
4848 Insights into the Translational Activation Mechanisms of the COX1 mRNA in Yeast Mitochondria
Zamudio-Ochoa, A.; Camacho-Villasana, Y.; Garcia-Guerrero, A. E.; Perez-Martinez, X.
10.1101/2024.11.01.621605 — molecular biology — Posted on 2024-11-03
4849 Phage CRISPR-like regulatory RNAs silence bacterial adaptive and innate immunity
Liu, C.; Wang, R.; Li, Z.; Wang, W.; Yao, J.; Cheng, F.; Du, X.; Guan, L.; Mestre, M. R.; Xue, Q.; Du, J.; Xu, J.; Zhou, T.; Shu, X.; Zhao, H.; Feng, Y.; Pinilla-Redondo, R.; Li, M.
10.1101/2024.10.29.618823 — microbiology — Posted on 2024-11-02
4854 Convergent evolution of epigenome recruited DNA repair across the Tree of Life
Monroe, G.; Lee, C.; Quiroz, D. P.; Lensink, M.; Oya, S.; Davis, M.; Long, E.; Bird, K. A.; Pierce, A. V.; Zhao, K.; Runcie, D. E.
10.1101/2024.10.15.618488 — genomics — Posted on 2024-11-02
4855 C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A
Mirceta, M.; Schmidt, M. H. M.; Shum, N.; Prasolava, T. K.; Meikle, B.; Lanni, S.; Mohiuddin, M.; Mckeever, P. M.; Zhang, M.; Liang, M.; van der Werf, I.; Scheers, S.; Dion, P. A.; Wang, P.; Wilson, M. D.; Abell, T.; Philips, E. A.; Sznajder, L. J.; Swanson, M. S.; Mehkary, M.; Khan, M.; Yokoi, K.; Jung, C.; de Jong, P. J.; Freudenreich, C. H.; McGoldrick, P.; Yuen, R. K. C.; Abrahao, A.; Keith, J.; Zinman, L.; Robertson, J.; Rogaeva, E.; Rouleau, G. A.; Kooy, R. F.; Pearson, C. E.
10.1101/2024.10.26.620312 — genetics — Posted on 2024-11-02
4856 Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
Wen, Z.; Li, P.; Yuan, Y.; Wang, C.; Li, M.; Wang, H.; Shi, M.; He, Y.; Cui, M.; Chen, L.; Sun, C.
10.1101/2024.02.20.581122 — microbiology — Posted on 2024-11-02
4857 Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies
Maurer, D. P.; Vu, M.; Ramos, A. S. F.; Dugan, H. L.; Khalife, P.; Geoghegan, J. C.; Walker, L. M.; Bajic, G.; Schmidt, A. G.
10.1101/2024.10.22.619298 — immunology — Posted on 2024-11-02
4858 Effect of Schizophrenia linked DRD2 gene mutations and correlation of social behavior with biochemical changes in a post-weaning isolated mouse model
Mukesh, N.; Divi, P. K.; Maikap, S.; Mohapatra, S.; Rajan, M.; Kanthimath, S.; Mishra, N.; Kar, K.; Anand, B. G.; Annamneedi, A.
10.1101/2023.11.02.565337 — neuroscience — Posted on 2024-11-02
4859 Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development
Caccavano, A. P.; Vlachos, A.; McLean, N.; Kimmel, S.; Kim, J. H.; Vargish, G.; Mahadevan, V.; Hewitt, L.; Rossi, A. M.; Spineux, I.; Wu, S. J.; Furlanis, E.; Dai, M.; Garcia, B. L.; Chittajallu, R.; London, E.; Yuan, X.; Hunt, S.; Abebe, D.; Eldridge, M. A. G.; Cummins, A. C.; Hines, B. E.; Plotnikova, A.; Mohanty, A.; Averbeck, B. B.; Zaghloul, K.; Dimidschstein, J.; Fishell, G.; Pelkey, K. A.; McBain, C. J.
10.1101/2024.01.20.576455 — neuroscience — Posted on 2024-11-02
4860 Neural Correlates of the Embodied Sense of Agency
Regev Krugwasser, A.; van der Goot, R.; Markusfeld, G.; Zvilichovsky, Y.; Salomon, R.
10.1101/2024.09.06.611665 — neuroscience — Posted on 2024-11-02
4867 Generating low-density minimizers
Golan, S.; Tziony, I.; Kraus, M.; Orenstein, Y.; Shur, A.
10.1101/2024.10.28.620726 — bioinformatics — Posted on 2024-11-02
4870 To impute or not to impute in untargeted metabolomics - that is the compositional question
Krutkin, D. D.; Thomas, S.; Zuffa, S.; Rajkumar, P.; Knight, R.; Dorrestein, P. C.; Kelley, S. T.
10.1101/2024.10.28.620738 — bioinformatics — Posted on 2024-11-02
4872 Early regional lymph node activation drives influenza vaccine responses in an ancestrally diverse cohort
Siu, J. H.; Coelho, S.; Palomeras, A.; Belij-Rammerstorfer, S.; Lee, C. H.; Strobel, T.; Thorpe, C.; Kaur, C.; Cole, T.; Remmert, N.; Fowler, J.; Pledger, S.; Dooley, K. B.; Opoka, D.; Szommer, T.; Vanderslott, S.; Kaleebu, P.; Milicic, A.; Palmer, D. B.; Lambe, T.; Marsden, B. D.; Koohey, H.; Coles, M.; Dendrou, C. A.; Pollock, K. M.
10.1101/2024.10.28.620725 — immunology — Posted on 2024-11-02
4875 Genomic prediction by modelling genotype by environment interaction for yield in groundnut
Lubanga, N.; Okaron, V.; Gimode, D. M.; Persa, R.; Mwololo, J.; Okello, D. K.; Ssemakula, M. O.; Odon, T. L.; Odeny, D. A.; Jarquin, D.
10.1101/2024.10.30.621054 — genomics — Posted on 2024-11-02
4878 Evolutionary history and rhizosphere microbial community composition in domesticated hops (Humulus lupulus L.)
McElwee-Adame, A.; Esplin-Stout, R.; Mugoya, T.; Vourlitis, G.; Welch, N.; Afram, K.; Ahmadi Jeshvaghane, M.; Bingham, N.; Dockter, A.; Eslava, J.; Gil, G.; Mergens, J.; Mohamed, A.; Nguyen, T.; Noor, F.; Salcedo, N.; Sethuraman, A.
10.1101/2024.10.30.621085 — evolutionary biology — Posted on 2024-11-02
4880 Detection of airborne Coccidioides spores using lightweight portable air samplers affixed to uncrewed aircraft systems in California's Central Valley
Radosevich, M. T.; Dobson, S.; Weaver, A. K.; Lampman, P. T. A.; Kollath, D. R.; Couper, L.; Campbell, G.; Taylor, J.; Remais, J. V.; Kobziar, L.; Markwiese, J.; Head, J. R.
10.1101/2024.10.28.620741 — ecology — Posted on 2024-11-02
4881 Trophic Interactions of Anopheles Gambiae Mosquito Larvae in Aquatic Ecosystem: A Metagenomics Approach
Karikari, A. S.; Akorli, J.; Gbogbo, F.; Ndong, I. C.; Karikari, A. B.; Karikari, A. A.; Kyerematen, R.; Agyenkwa-Mawuli, K.; Gyimah, T.; Aboagye-Antwi, F.
10.1101/2024.11.01.621049 — ecology — Posted on 2024-11-02
4883 Targeted disruption of linkage-specific ubiquitylation reveals a key role of K29-linked ubiquitylation in epigenome integrity
Arroyo-Gomez, J.; Wang, J.; Guerillon, C.; Isaakova, E.; Reveron-Gomez, N.; Koutrouli, M.; Rahmanto, A. S.; Mitrofanov, K.; Ingham, A.; Schovsbo, S.; Weischenfeldt, K.; Coscia, F.; Typas, D.; Volker-Albert, M.; Solis, V.; Juhl Jensen, L.; Groth, A.; Mund, A.; Beli, P.; Shearer, R. F.; Mailand, N.
10.1101/2024.10.29.620783 — cell biology — Posted on 2024-11-02
4884 Mapping the druggable targets displayed by human colonic enteroendocrine cells
Lei, Y.; Bohl, B.; Meyer, L.; Jacobs, M.; Haq, N.; Yang, X.; Hayee, B. H.; Murphy, K. G.; Hashemi, P.; Bewick, G. A.
10.1101/2024.10.29.620704 — cell biology — Posted on 2024-11-02
4885 FLEXIBLE, PRODUCTION-SCALE, HUMAN WHOLE GENOME SEQUENCING ON A BENCHTOP SEQUENCER
Green, K.; Krajacich, B.; Wiseman, K.; Mains, P. T.; Robertson, S.; Billings, S.; Sudkamp, M.; Lo, C. S.; Lajoie, B. R.; Kruglyak, S.; Levy, S.; Zhao, J.
10.1101/2024.11.01.620975 — molecular biology — Posted on 2024-11-02
4887 A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T helper cell signaling, differentiation and epigenetic remodeling
Golec, D. P.; Gazzinelli-Guimaraes, P.; Chauss, D.; Nagashima, H.; Yu, K.; Hill, T.; Nivelo, L.; Cannons, J. L.; Perry, J.; Joshi, I.; Pereira, N.; Oliveira, F. M. S.; Cruz, A. C.; Druey, K. M.; Lack, J. B.; Nutman, T. B.; Villarino, A. V.; O'Shea, J. J.; Afzali, B.; Schwartzberg, P. L.
10.1101/2024.10.28.620691 — immunology — Posted on 2024-11-02
4888 Embryonic Mast Cells Arise from Cpa3-expressing Precursors Independent of Granulocyte-Monocyte Progenitors
Ma, W.; Chen, H.; Gao, F.; Zhao, H.; Wu, N.; Zhang, S.; Zhu, Y.; Xu, Z.; Lan, Y.; Liu, B.; Ye, Y.; Liu, Z.; Ginhoux, F.; Su, B.
10.1101/2024.10.30.620640 — immunology — Posted on 2024-11-02
4889 Interplay of human macrophage response and natural resistance of L. (V.) panamensis to pentavalent antimony
Fernandez, O. L.; Belew, A. T.; Sanchez-Hidalgo, A.; Rosales-Chilama, M.; Colmenares, M.; Saravia, N. G.; El-Sayed, N. M.
10.1101/2024.10.29.620724 — immunology — Posted on 2024-11-02
4893 Using BONCAT To Dissect The Proteome Of S. aureus Persisters
George Matlalcuatzi, E. D. C.; Bakkum, T.; Thomas, P. S.; Hacker, S. M.; Florea, B. I.; Vriesendorp, B.; Rozen, D.; van Kasteren, S. I.
10.1101/2024.11.01.621614 — microbiology — Posted on 2024-11-02
4895 Intraductal infection with H5N1 clade 2.3.4.4b influenza virus
Roubidoux, E. K.; Meliopoulos, V. A.; Livingston, B.; Brigleb, P. H.; Schultz-Cherry, S.
10.1101/2024.11.01.621606 — microbiology — Posted on 2024-11-02
4897 Collagen binding adhesin restricts Staphylococcus aureus skin infection
Bhattacharya, M.; Spencer, B. L.; Kwiecinski, J. M.; Podkowik, M.; Putzel, G.; Pironti, A.; Shopsin, B.; Doran, K. S.; Horswill, A. R.
10.1101/2024.11.01.621145 — microbiology — Posted on 2024-11-02
4900 Network-based representation learning reveals the impact of time and diet on the gut microbial and metabolomic environment of infants
Price, A.; Rasolofomanana Rajery, S.; Manpearl, K.; Robertson, C. E.; Krebs, N. F.; Frank, D. N.; Hendricks, A. E.; Krishnan, A.; Tang, M.
10.1101/2024.11.01.621627 — microbiology — Posted on 2024-11-02
4902 Isoprene deters insect herbivory by priming plant hormone responses
Sahu, A.; Mostofa, M. G.; Xu, Y.; Serda, B.; O'Keefe, J.; Sharkey, T. D.
10.1101/2024.11.01.621578 — plant biology — Posted on 2024-11-02
4903 The role of the LysR-type transcription factor PacR in regulating nitrogen metabolism in Anabaena sp. PCC7120
Werner, E.; Huokko, T.; Santana-Sanchez, A.; Picossi, S.; Nikkanen, L.; Herrero, A.; Allahverdiyeva, Y.
10.1101/2024.11.01.621236 — plant biology — Posted on 2024-11-02
4909 Regulation of heterosis-associated gene expression complementation in maize hybrids
Pitz, M.; Baldauf, J. A.; Piepho, H.-P.; Yu, P.; Schoof, H.; Mason, A. S.; Li, G.; Hochholdinger, F.
10.1101/2024.10.30.620956 — plant biology — Posted on 2024-11-02
4915 Breast tumor microbiome regulates anti-tumor immunity and T cell-associated metabolites
Liu, C.-C.; Grencewicz, D.; Chakravarthy, K.; Li, L.; Liepold, R.; Wolf, M.; Sangwan, N.; Tzeng, A.; Hoyd, R.; Jhawar, S. R.; Grobmyer, S. R.; Al-Hilli, Z.; Sciallis, A. P.; Spakowicz, D.; Ni, Y.; Eng, C.
10.1101/2024.10.29.620864 — cancer biology — Posted on 2024-11-02
4916 AnnotIEM: novel tool for microbiome species-level annotation of 16S gene based microbial sequencing
Bhatttacharyya, M.; Rauer, L.; Reiger, M.; Afgani, J.; Huelpuesch, C.; Traidl-Hoffmann, C.; Neumann, A. U.
10.1101/2024.10.31.621263 — bioinformatics — Posted on 2024-11-02
4917 Microbial lysates as low-cost serum replacements in cellular agriculture media formulation
Dolgin, J.; Chakravarty, D.; Sullivan, S. F.; Cai, Y.; Lim, T.; Yamaguchi, P.; Balkan, J. E.; Xu, L.; Olawoyin, A. D.; Lee, K.; Kaplan, D. L.; Nair, N. U.
10.1101/2024.10.28.620756 — bioengineering — Posted on 2024-11-02
4920 Species-specific phyllosphere responses to external pH change
Lopez Gonzalez, C.; Floc'h, J.-B.; Renner, T.; Gilbert, K. J.
10.1101/2024.11.01.621601 — plant biology — Posted on 2024-11-02
4921 Genomic and Phenomic Prediction for Soybean Seed Yield, Protein, and Oil
Van der Laan, L.; Parmley, K.; Saadati, M.; Torres Pacin, H.; Panthulugiri, S.; Sarkar, S.; Ganapathysubramanian, B.; Lorenz, A. J.; Singh, A. K.
10.1101/2024.11.01.621550 — plant biology — Posted on 2024-11-02
4923 SOQ1 functions as a methionine sulfoxide reductase in the chloroplast lumen for regulation of photoprotective qH in Arabidopsis
Hao, J.; Johansson, A.; Svensson Fall, J.; Duan, J.; Hertle, A. P.; Brooks, M. D.; Niyogi, K. K.; Yoshida, K.; Hisabori, T.; Malnoe, A.
10.1101/2024.11.01.621559 — plant biology — Posted on 2024-11-02
4931 Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice
Bruter, A. V.; Varlamova, E. A.; Stavskaya, N. I.; Antysheva, Z. G.; Manskikh, V. N.; Tvorogova, A. V.; Korshunova, D. S.; Khamidullina, A. I.; Utkina, M. V.; Bogdanov, V. P.; Baikova, I. P.; Nikiforova, A. I.; Albert, E. A.; Maksimov, D. O.; Li, J.; Chen, M.; Schools, G. P.; Feoktistov, A. V.; Shtil, A. A.; Roninson, I. B.; Mogila, V. A.; Silaeva, Y. Y.; Tatarskiy, V. V.
10.1101/2023.11.04.564913 — developmental biology — Posted on 2024-11-02
4932 The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy
Chopra, A.; Xylaki, M.; Yin, F.; Castro-Hernandez, R.; Merghani, M.; Grande, V.; Mollenhauer, B.; Fischer, A.; Outeiro, T. F.
10.1101/2024.09.12.612649 — neuroscience — Posted on 2024-11-02
4933 Neurocognitive Mechanism of Radiologists Perceptual Errors: Results of Preliminary Studies
Bruno, M. A.; Krupinski, E. A.; Bunce, S. C.; Baird, G.; Mills, C.; Karunanayaka, P.; Egeth, H.; Chang, R.; Cottrill, R.; Jump, S.; Sathian, K.; Mosher, T. J.
10.1101/2024.04.29.591746 — neuroscience — Posted on 2024-11-02
4935 Solution-phase indexing by kinetic confinement enables rapid, simple, and instrument-free single cell transcriptional profiling
Marafini, P.; Smith, D. G.; Lamstaes, A. R.; Contreras, R. E.; Williams, I.; West, I.; Ambridge, O.; Sanders-Brown, V.; Intaite, E.; Hii, C. Y.; Hume, B. C.; Munagala, U.; Plumbly, W.; Brown, F. L.; Shlyakhtina, Y.; Woods, L.; Bibby, J. A.; Williams, L.; Yang, J. H.; Steffy, B.; Zawada, L.; Harger, J. W.; McKenzie, D.; Laing, A. G.; Stubbington, M. J.; Edelman, L. B.
10.1101/2024.11.01.621570 — genomics — Posted on 2024-11-02
4936 Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification
Otjacques, E.; Paula, J. R.; Ruby, E. G.; Xavier, J.; McFall-Ngai, M. J.; Rosa, R.; Schunter, C.
10.1101/2024.10.31.621237 — ecology — Posted on 2024-11-02
4937 Single-cell, spatial, and fate-mapping analyses uncover niche dependent diversity of cochlear myeloid cells.
Chiot, A.; Felgner, M. J.; Brownell, D.; Rott, K. H.; Bogachuk, A.; Rosmus, D.-D.; Masuda, T.; Ching, A.; Atkinson, P. J.; Prinz, M.; Sachs, K.; Cheng, A. G.; Wieghofer, P.; Ajami, B.
10.1101/2024.10.30.621184 — immunology — Posted on 2024-11-02
4939 High-throughput single molecule microscopy with adaptable spatial resolution using exchangeable oligonucleotide labels
de Zwaan, K.; Huo, R.; Hensgens, M.; Wienecke, H. L.; Tekpinar, M.; Geertsema, H.; Grussmayer, K. S.
10.1101/2024.10.30.621026 — biophysics — Posted on 2024-11-02
4949 Impaired axonal transport at the optic nerve head contributes to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucoma
Kaipa, B. R.; Kasetti, R.; Sundaresan, Y.; Li, L.; Yacoub, S.; Millar, C.; Cho, W.; Skowronska-Krawczyk, D.; Maddineni, P.; Palczewski, K.; zode, g.
10.1101/2024.09.18.613712 — neuroscience — Posted on 2024-11-02
4950 Cross-species transmission of human hepatitis B virus to wild Neotropical primates
boubli, J.; El Bizri, H.; Botelho-Souza, L.; Gubili, C.; Martin, S.; Araujo, M.; Burch, T.; Messias, M.; Santos, A.; Osaki, L.; Pereira, A.; Katsuragawa, T.; Passos-Silva, A.; Gil, L.; Farias, I.; Salcedo, J.; Vieira, D.
10.1101/2024.10.31.621242 — pathology — Posted on 2024-11-02
4951 Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk
Coveney, C. R.; Maridas, D.; Chen, H.; Muthuirulan, P.; Liu, Z.; Jagoda, E.; Yarlagadda, S.; Movaheddi, M.; Proffen, B.; Rosen, V.; Kiapour, A. M.; Capellini, T. D.
10.1101/2024.11.01.621374 — genetics — Posted on 2024-11-02
4954 Neutrophil transcriptome diverges into two discrete trajectories in a murine model of severe Streptococcus pneumoniae pneumonia
Pihl, R. M. F.; Alabdullatif, S. H.; Hiller, B. E.; Armstrong, E. M. R.; Martins, K. R.; Dimbo, E. L.; Lee, Y.; Campbell, J. D.; Gower, A. C.; Mizgerd, J. P.; Quinton, L. J.; Traber, K. E.
10.1101/2024.10.29.620672 — immunology — Posted on 2024-11-02
4955 TILLCANN: A TILLING platform in Cannabis sativa for mutation discovery and crop improvement
Duarte-Delgado, D.; Alexiou, K. G.; Pujol, M.; Uauy, C.; Adamski, N. M.; Vidal, V.; Torres, A.; Zalewski, C.; Gaudino, R.; Monfort, A.; Argyris, J.
10.1101/2024.10.28.620663 — plant biology — Posted on 2024-11-01
4957 Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model
Yang, J.; Riemann, S. B.; Lyu, J.; Feng, S.; Bi, Y.; Lentini, N. A.; Kang, I.; Kashemirov, B. A.; Hartline, C. B.; James, S. H.; Tollefson, A. E.; Cline-Smith, A.; Toth, K.; McKenna, C. E.
10.1101/2024.11.01.621456 — biochemistry — Posted on 2024-11-01
4958 Sharing the Spotlight: Uncovering common attentional dynamics across species
Glukhova, M.; Tlaie, A.; Muresan, R.; Taylor, R.; Ferracci, P.-A.; Shapcott, K.; Arne, O.; Ciuparu, A.; Havenith, M. N.; Schölvinck, M. L.
10.1101/2024.11.01.621490 — animal behavior and cognition — Posted on 2024-11-01
4960 Genomics and resistance assays inform the management of two tree species being devastated by the invasive myrtle rust pathogen
Chen, S. H.; Yap, J.-Y. S.; Viler, V.; Stehn, C.; Sandhu, K. S.; Percival, J.; Pegg, G. S.; Menzies, T.; Jones, A.; Guo, K.; Giblin, F. R.; Cohen, J.; Edwards, R. J.; Rossetto, M.; Bragg, J. G.
10.1101/2024.10.30.612564 — genomics — Posted on 2024-11-02
4963 Genetically based variation in fitness and carbon assimilation among bur oak populations
Rea, L. M. S.; Ostrowsky, L.; Mohn, R.; Garner, M.; Lapadat, C.; McCarthy, H. R.; Hipp, A. L.; Cavender-Bares, J.
10.1101/2024.10.30.620350 — ecology — Posted on 2024-11-01
4965 Structure determinants of DANGEROUS MIX 3, an alpha/beta hydrolase, for triggering NLR-mediated genetic incompatibility in plants
Kim, G.; Wan, W.-L.; Kim, N.; Tan, Y. Y.; Charoennit, N.; Lee, R. R. Q.; Liew, Y. Y.; Ng, S. K.; Zhang, Y.; Song, J.-J.; Chae, E.
10.1101/2024.10.28.620575 — plant biology — Posted on 2024-11-01
4966 Nondestructive Seed Genotyping via Microneedle-Based DNA Extraction
Li, M.; Poonam, A. D.; Cui, Q.; Hsieh, T.; Jagadeesan, S.; Bruce, W.; Vogel, J. T.; Sessions, A.; Cabrera, A.; Saville, A. C.; Ristaino, J.; Paul, R.; Wei, Q.
10.1101/2024.10.28.620740 — plant biology — Posted on 2024-11-01
4967 Bacterial cell-free DNA profiling reveals co-elevation of multiple bacteria in newborn foals with suspected sepsis
Chen, L.-T.; Wesdorp, E.; Jager, M.; Siegers, E. W.; Theelen, M. J. P.; Besselink, N.; Vermeulen, C.; Zomer, A. L.; Broens, E. M.; Wagenaar, J. A.; de Ridder, J.
10.1101/2024.10.31.620104 — pathology — Posted on 2024-11-01
4976 Genomic evidence suggests the balanced lethal system in Triturus newts originated in an instantaneous speciation event.
France, J. M.; de Visser, M. C.; Paulouskaya, O.; Arntzen, J. W.; Babik, W.; Cvijanovic, M.; Ivanovic, A.; Smith, J.; Vuicc, T.; Wielstra, B.
10.1101/2024.10.29.620207 — evolutionary biology — Posted on 2024-11-01
4979 The evolutionary history and modern diversity of triterpenoid cyclases
McShea, H.; Viens, R. A.; Olagunju, B. O.; Giner, J.-L.; Welander, P. V.
10.1101/2024.10.28.620730 — evolutionary biology — Posted on 2024-11-01
4982 Role of Arginine and its Metabolism in TGF-β-Induced Activation of Lung Fibroblasts
Hamanaka, R. B.; Shin, K. W. D.; Atalay, M. V.; Cetin-Atalay, R.; Shah, H.; Houpy Szafran, J. C.; Woods, P. S.; Meliton, A. Y.; Shamaa, O. R.; Cho, T.; Tian, Y.; Mutlu, G. M.
10.1101/2024.11.01.618293 — cell biology — Posted on 2024-11-01
4983 Proposal of Patescibacterium danicum gen. nov., sp. nov. in the ubiquitous ultrasmall bacterial phylum Patescibacteriota phyl. nov.
Dutkiewicz, Z.; Singleton, C. M.; Sereika, M.; Villada, J. C.; Mussig, A. J.; Chuvochina, M.; Albertsen, M.; Schulz, F.; Woyke, T.; Nielsen, P. H.; Hugenholtz, P.; Rinke, C.
10.1101/2024.11.01.618662 — microbiology — Posted on 2024-11-01
4984 ProteinWeaver: A Webtool to Visualize Ontology-Annotated Protein Networks
Anderson, O. F.; Barelvi, A. A.; O'Brien, A.; Norman, A.; Jan, I.; Ritz, A.
10.1101/2024.10.24.620032 — systems biology — Posted on 2024-11-01
4985 Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse Glomeruli
Ali, A.; liu, z.; Ye, K.; Guan, Y.; Chen, S.; Lii, T.; Guo, Z.; Wong, M. K.; Vasquez, P.; Poudel, C.; Mustonen, B. C.; Eng, D.; Pippin, J.; Shankland, S. J.; Wang, S.; Vaughan, J. C.
10.1101/2024.10.31.620364 — physiology — Posted on 2024-11-01
4986 Transcriptional phenotype of the anti-parasitic benzodiazepine meclonazepam on the blood fluke Schistosoma mansoni
Henthorn, C. R.; McCusker, P.; Le Clec'h, W.; Chevalier, F. D.; Anderson, T. J.; Zamanian, M.; Chan, J. D.
10.1101/2024.10.29.620505 — pharmacology and toxicology — Posted on 2024-11-01
4987 Tandem-repeat proteins introduce tuneable properties to engineered biomolecular condensates
Ng, T. L. C.; Hoare, M. P.; Maristany, M. J.; Wilde, E. J.; Sneideris, T.; Huertas, J.; Agbetiameh, B. K.; Furukawa, M.; Joseph, J. A.; Knowles, T. P. J.; Collepardo-Guevara, R.; Itzhaki, L. S.; Kumita, J. R.
10.1101/2024.04.16.589709 — biophysics — Posted on 2024-11-01
4991 Systematic dissection of epigenetic age acceleration in normal breast tissue reveals its link to estrogen signaling and cancer risk
Sehl, M. E.; Guo, W.; Farrell, C.; Marino, N.; Henry, J. E.; Storniolo, A. M.; Papp, J.; Li, J. J.; Horvath, S.; Pellegrini, M.; Ganz, P. A.
10.1101/2024.10.31.619735 — bioinformatics — Posted on 2024-11-01
4992 In vivo genome editing of human hematopoietic stem cells for treatment of blood disorders by mRNA delivery
Xu, S.; Liang, D.; Wang, Q.; Cheng, Y.; Xie, D.; Gui, Y.; Zhang, H.; Zhao, F.; Ren, W.; Sun, G.; Yang, Y.; Li, L.; Lai, Y.; Fu, B.; Lu, Y.; Wang, Z. J.; Wu, Y.
10.1101/2024.10.28.620445 — bioengineering — Posted on 2024-11-01
4994 The dinucleotide structure of NAD enables specific reduction on mineral surfaces
Pereira, D. P. H.; Xie, X.; Beyazay, T.; Paczia, N.; Subrati, Z.; Belz, J.; Volz, K.; Tueysuez, H.; Preiner, M.
10.1101/2024.10.11.617347 — evolutionary biology — Posted on 2024-11-01
4995 Evidences that host genetic background more than the environment shapes the microbiota of the snail Bulinus truncatus, an intermediate host of Schistosoma species.
Jaquet, M. J.; Douchet, P.; Toulza, E.; Lefevre, T.; Senghor, B.; Boissier, J.; Lepais, O.; Chancerel, E.; Gourbal, B.; Rey, O.
10.1101/2024.11.01.619350 — ecology — Posted on 2024-11-01
5004 Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
Wen, Z.; Li, P.; Yuan, Y.; Wang, C.; Li, M.; Wang, H.; Shi, M.; He, Y.; Cui, M.; Chen, L.; Sun, C.
10.1101/2024.02.20.581122 — microbiology — Posted on 2024-11-01
5007 Daily electric field treatment improves functional outcomes after thoracic contusion spinal cord injury in rats
Harland, B.; Matter, L.; Lopez, S.; Fackelmeier, B.; Hazelgrove, B.; Meissner, S.; O'Carroll, S.; Raos, B.; Asplund, M.; Svirskis, D.
10.1101/2024.11.01.621450 — neuroscience — Posted on 2024-11-01
5008 Tcf4 Deficiency Causes Recurrent Seizures in Mice
Craciun, L.; DeNittis, V. R.; Davis, M. T.; Paz, J. T.; Saijo, K.
10.1101/2024.11.01.621590 — neuroscience — Posted on 2024-11-01
5009 Phenotypic complexities of rare heterozygous neurexin-1 deletions
Fernando, M. B.; Fan, Y.; Zhang, Y.; Tokolyi, A.; Murphy, A. N.; Kammourh, S.; Deans, M. P.; Ghorbani, S.; Onatzevitch, R.; Pero, A.; Padilla, C.; Williams, S.; Flaherty, E. K.; Prytkova, I. A.; Cao, L.; Knowles, D. A.; Fang, G.; Slesinger, P. A.; Brennand, K.
10.1101/2023.10.28.564543 — neuroscience — Posted on 2024-11-01
5011 Consistent hierarchies of single-neuron timescales in mice, macaques and humans
Zeisler, Z. R.; Love, M.; Rutishauser, U.; Stoll, F. M.; Rudebeck, P. H.
10.1101/2024.10.30.621133 — neuroscience — Posted on 2024-11-01
5012 Lateralized nodose ganglia gene expression implicates cholecystokinin receptors in interoceptive reward signaling
Welch, H. F.; Sankaranarayanan, I.; Hong, V. M.; Mazhar, K.; Kolber, B. J.; Price, T. J.; Thorn, C. A.
10.1101/2024.11.01.621506 — neuroscience — Posted on 2024-11-01
5014 Electroconvulsive therapy generates a hidden wave after seizure
Rosenthal, Z.; Majeski, J.; Somarowthu, A.; Quinn, D.; Lindquist, B.; Putt, M.; Karaj, A.; Favilla, C.; Baker, W.; Hosseini, G.; Rodriguez, J.; Cristancho, M.; Sheline, y.; Shuttleworth, B.; Abbott, C.; Yodh, A.; Goldberg, E.
10.1101/2024.10.31.621357 — neuroscience — Posted on 2024-11-01
5016 Prefrontal 5α-reductase 2 mediates male-specific acute stress response
Cadeddu, R.; Braccagni, G.; Floris, G.; Branca, C.; Corridori, E.; Salviati, S.; Sanchez, P.; Santovito, L. S.; Torres, J. M.; Ortega, E.; Pinna, G.; Moos, P. J.; Scheggi, S.; Bortolato, M.
10.1101/2024.05.07.593076 — neuroscience — Posted on 2024-11-01
5019 A subset of brain regions within adult functional connectivity networks demonstrate high reliability across early development
Tu, J. C.; Wang, Y.; Wang, X.; Dierker, D.; Sobolewski, C. M.; Day, T. K. M.; Kardan, O.; Miranda Dominguez, O.; Moore, L. A.; Feczko, E. J.; Fair, D. A.; Elison, J. T.; Gordon, E. M.; Laumann, T. O.; Eggebrecht, A. T.; Wheelock, M. D.
10.1101/2024.07.31.606025 — neuroscience — Posted on 2024-11-01
5020 Mitochondrial Stress Disassembles Nuclear Architecture through Proteolytic Activation of PKCδ and Lamin B1 Phosphorylation in Neuronal Cells: Implications for Pathogenesis of Age-related Neurodegenerative Diseases
Charli, A.; Luo, J.; Palanisamy, B.; Malovic, E.; Riyaz, Z.; Miller, C.; Chang, Y.-T.; Samidurai, M.; Zenitsky, G.; Jin, H.; anantharam, v.; Kanthasamy, A.; Kanthasamy, A.
10.1101/2024.11.01.621517 — neuroscience — Posted on 2024-11-01
5021 Astrocytes control UP state and slow oscillation periodicity in human cortical networks
Crowe, J. A.; Bazzari, A. H.; Nagel, D. A.; Sokolovski, S. G.; Rafailov, E. U.; Hill, E. J.; Parri, R. H.
10.1101/2024.11.01.621156 — neuroscience — Posted on 2024-11-01
5022 Cognitive control of behavior and hippocampal information processing without medial prefrontal cortex
Park, E.; Reilly, K. O.; Grubbs, G.; Taborga, D.; Nicholas, K.; Ahmeda, A. S.; Ruiz, N.; Kim, N.; Segura-Carrillo, S.; Fenton, A. A.
10.1101/2019.12.20.884262 — neuroscience — Posted on 2024-11-01
5023 Functional diversity in the output of the primate retina
Kling, A.; Cooler, S.; Manookin, M.; Rhoades, C. E.; Brackbill, N.; Field, G.; Rieke, F.; Sher, A.; Litke, A.; Chichilnisky, E. J.
10.1101/2024.10.31.621339 — neuroscience — Posted on 2024-11-01
5025 Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans
Pant, R.; Pitchaimuthu, K.; Ossandon, J. P.; Shareef, I.; Lingareddy, S.; Finsterbusch, J.; Kekunnaya, R.; Röder, B.
10.1101/2024.04.18.590147 — neuroscience — Posted on 2024-11-01
5026 A chaotrope-based approach for rapid in vitro assembly and loading of bacterial microcompartment shells
Range, K. L.; Chiang, T. K.; Pramanik, A.; Landa, J. F.; Snyder, S. N.; Zuo, X.; Tiede, D. M.; Utschig, L. M.; Hegg, E. L.; Sutter, M.; Kerfeld, C.
10.1101/2024.10.31.621445 — synthetic biology — Posted on 2024-11-01
5028 Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML
Zeng, A. G. X.; Iacobucci, I.; Shah, S.; Mitchell, A.; Wong, G.; Bansal, S.; Chen, D.; Gao, Q.; Kim, H.; Kennedy, J. A.; Minden, M. D.; Haferlach, T.; Mullighan, C. G.; Dick, J. E.
10.1101/2023.12.26.573390 — cancer biology — Posted on 2024-11-01
5029 Mediator Subunit Med4 Enforces Metastatic Dormancy in Breast Cancer
Bae, S.-Y.; Ling, H.-H.; Chen, Y.; Chen, H.; Kumar, D.; Zhang, J.; Viny, A. D.; DePinho, R. A.; Giancotti, F. G.
10.1101/2023.11.18.566087 — cancer biology — Posted on 2024-11-01
5030 A novel feeding mechanism: Sunbirds drink nectar via intralingual suction
Cuban, D.; Wang-Claypool, C.; Dalimunthe, Y.; Downs, C. T.; Bowie, R. C. K.; Brau, F.; Johnson, S.; Rico-Guevara, A.
10.1101/2024.05.14.594085 — biophysics — Posted on 2024-11-01
5032 HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data
Mao, H.; Jia, M.; Di, M.; Valenzi, E.; Cai, X. T.; Singh, H.; Lafyatis, R. A.; Zhang, K.; Benos, P. V.
10.1101/2022.10.17.512602 — bioinformatics — Posted on 2024-11-01
5033 TFAM as a sensor of UVC-induced mitochondrial DNA damage
King, D. E.; Beard, E. E.; Satusky, M. J.; Ryde, I. T.; George, A.; Johnson, C.; Dolan, E. L.; Zhang, Y.; Zhu, W.; Wilkins, H.; Corden, E.; Murphy, S. K.; Erie, D.; Gordan, R.; Meyer, J. N.
10.1101/2024.10.24.620005 — biochemistry — Posted on 2024-11-01
5038 Analysis of sparse animal social networks
Mylne, H. K.; Abell, J.; Beale, C. M.; Brent, L. J. N.; Bro-Jorgensen, J.; Evans, K. E.; Hart, J. D. A.; Sakala, D.; Simpamba, T.; Youldon, D.; Franks, D. W.
10.1101/2024.10.31.621436 — animal behavior and cognition — Posted on 2024-11-01
5039 CFC-seq: identification of full-length capped RNAs unveil enhancer-derived transcription
Yip, C. W.; Parr, C.; Takahashi, H.; Yasuzawa, K.; Valentine, M.; Nishiyori-Sueki, H.; Ugolini, C.; Ranzani, V.; Murata, M.; Kato, M.; Kang, W.; Yip, W. H.; Shibayama, Y.; Sim, A. D.; Chen, Y.; Shu, X.; Moody, J. D.; Umarov, R.; Chang, J.-C.; Pandolfini, L.; Kawashima, T.; Tagami, M.; Nobusada, T.; Kouno, T.; Alfonso Gonzalez, C.; Albanese, R.; Dossena, F.; Haberman, N.; Ozaki, K.; Kasukawa, T.; Lenhard, B.; Frith, M.; Bodega, B.; Nicassio, F.; Calviello, L.; Bienko, M.; Legnini, I.; Hilgers, V.; Gustincich, S.; Goeke, J.; Lecellier, C. H.; Shin, J. W.; Hon, C.-C.; Carninci, P.
10.1101/2024.10.31.620483 — genomics — Posted on 2024-11-01
5043 Multi-modal characterization of rodent tooth development
Jiang, Y.; Katsura, K. A.; Badt, N. Z.; Didziokas, M.; Dougherty, S.; Goldsby, D. L.; Bhoj, E. J.; Vining, K. H.
10.1101/2024.11.01.621612 — developmental biology — Posted on 2024-11-01
5044 Heart tube morphogenesis is regulated by segment-specific gene regulatory networks controlled by MEF2C
Muncie-Vasic, J. M.; Sinha, T.; Clark, A. P.; Brower, E. F.; Saucerman, J. J.; Black, B. L.; Bruneau, B. G.
10.1101/2024.11.01.621613 — developmental biology — Posted on 2024-11-01
5046 Deficiency of mitophagy mediator Parkin in aortic smooth muscle cells exacerbates abdominal aortic aneurysm
Wang, H.; Kazaleh, M.; Gioscia-Ryan, R. A.; Millar, J.; Temprano-Sagrera, G.; Wood, S.; Van Den Burgh, F.; Blin, M. G.; Wragg, K. M.; Luna, A.; Hawkins, R. B.; Soleimanpour, S. A.; Sabater-Lleal, M.; Shu, C.; Beard, D. A.; Ailawadi, G.; Deng, J. C.; Goldstein, D. R.; Salmon, M.
10.1101/2024.10.30.621201 — molecular biology — Posted on 2024-11-01
5048 Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment
Tolman, N.; Li, T.; Balasubramanian, R.; Li, G.; Bupp-Chickering, V.; Kelly, R. A.; Simon, M.; Peregrin, J.; Montgomery, C.; Stamer, W. D.; Qian, J.; John, S. W. M.
10.1101/2024.11.01.621152 — molecular biology — Posted on 2024-11-01
5051 Novel symbionts reveal amoebae as significant hosts for environmental chlamydiae
Liu, F.; Walker, L. M.; Wolf, J.; Thompson, C.; Haselkorn, T. S.; Shi, Y.; Ding, J.; Strassmann, J. E.; Queller, D.; Shu, L.
10.1101/2024.11.01.621453 — microbiology — Posted on 2024-11-01
5054 Acute and early stress axis modulation in joint disease permanently reduces pain and emotional comorbidities
Hestehave, S.; Florea, R.; Singleton, S.; Fedorec, A. J. H.; Caxaria, S.; Morgan, O. B.; Kopp, K. T.; Brown, L.; Heymann, T.; Sikandar, S.; Hausch, F.; Peirson, S. N.; Geranton, S. M.
10.1101/2024.11.01.621278 — neuroscience — Posted on 2024-11-01
5055 DJ-1 mediates regulation of metabolism and immune response in Parkinsons disease astrocytes and Glioblastoma cells
Mencke, P.; Ohnmacht, J.; Jeannelle, F.; Ries, A. J.; de la Maza, M. M.; Ullrich, M.; Massart, F.; Mulica, P.; Badanjak, K.; Hanss, Z.; Rybicki, A.; Antony, P.; Delcambre, S.; Arena, G.; Cruciani, G.; Jarazo, J.; Gavotto, F.; Jaeger, C.; Ewen, A.; Pacheco, M. P.; Brenner, D.; Schwamborn, J. C.; Sauter, T.; Sinkkonen, L.; Dittmar, G.; Bouvier, D.; Meiser, J.; Gruenewald, A.; Bonifati, V.; Platten, M.; Krueger, R.; Boussaad, I.
10.1101/2024.10.31.621212 — neuroscience — Posted on 2024-11-01
5057 Mitochondrial NADK2-dependent NADPH controls Tau oligomer uptake in human neurons
Pardo, E. C.; Kim, T.; Wallrabe, H.; Zengeler, K. E.; Sagar, V. K.; Mingledorff, G.; Sun, X.; Periasamy, A.; Lukens, J. R.; Bloom, G. S.; Norambuena, A.
10.1101/2024.10.31.621392 — neuroscience — Posted on 2024-11-01
5059 Consolidation of Sequential Planning
Vikbladh, O. M.; Russek, E. M.; Burgess, N.
10.1101/2024.11.01.621475 — neuroscience — Posted on 2024-11-01
5060 Simultaneous mesoscopic measurement and manipulation of mouse cortical activity
Matveev, P.; Li, A. J.; Ye, Z.; Bowen, A. J.; Opitz-Araya, X.; Ting, J. T.; Steinmetz, N. A.
10.1101/2024.11.01.621418 — neuroscience — Posted on 2024-11-01
5061 Brain functional connectivity, but not neuroanatomy, captures the interrelationship between sex and gender in preadolescents
Metoki, A.; Chauvin, R. J.; Gordon, E. M.; Laumann, T. O.; Kay, B. P.; Krimmel, S. R.; Marek, S.; Wang, A.; Van, A. N.; Baden, N. J.; Suljic, V.; Scheidter, K. M.; Monk, J.; Whiting, F. I.; Ramirez-Perez, N. J.; Barch, D. M.; Sotiras, A.; Dosenbach, N. U. F.
10.1101/2024.10.31.621379 — neuroscience — Posted on 2024-11-01
5062 Viral vector-mediated SLC9A6 gene replacement reduces cerebellar dysfunction in the shaker rat model of Christianson syndrome
Anderson, C. J.; Figueroa, K. P.; Paul, S. J.; Gandelman, M.; Dansithong, W.; Katakowski, J. A.; Scoles, D. R.; Pulst, S. M.
10.1101/2024.10.31.621435 — neuroscience — Posted on 2024-11-01
5066 Functionally Adaptive Structural Basis Sets of the Brain: A Dynamic Fusion Approach
Duda, M.; Chen, J.; Belger, A.; Ford, J.; Mathalon, D.; Preda, A.; Turner, J. A.; Van Erp, T.; Pearlson, G. D.; Calhoun, V.
10.1101/2024.06.18.599621 — neuroscience — Posted on 2024-11-01
5068 Structural Model of Bacteriophage P22 Scaffolding Protein in a Procapsid by Magic-Angle Spinning NMR
Guo, C.; Whitehead, R. D.; Struppe, J.; Porat-Dahlerbruch, G.; Hassan, A.; Gronenborn, A. M.; Alexandrescu, A.; Teschke, C. M.; Polenova, T. M.
10.1101/2024.11.01.621488 — biochemistry — Posted on 2024-11-01
5070 Structural basis of pseudoGTPase-mediated protein-protein interactions
Wang, B.; Yang, R.; Wan, C.; Tian, Y.; Wu, J.; Roy, S.; Li, S.; Shen, J.; Yin, Q.
10.1101/2024.10.30.620932 — biochemistry — Posted on 2024-11-01
5072 A Structural Mechanism for Noncanonical GPCRSignal Transduction in the Hedgehog Pathway
Steiner, W. P.; Iverson, N.; Venkatakrishnan, V.; Wu, J.; Stepniewski, T. M.; Michaelson, Z.; Broeckel, J.; Zhu, J.-F.; Bruystens, J.; Lee, A.; Nelson, I.; Bertinetti, D.; Arveseth, C. D.; Tan, G.; Spaltenstein, P.; Xu, J.; Huttenhain, R.; Kay, M.; Herberg, F. W.; Selent, J.; Anand, G. S.; Dunbrack, R. L.; Taylor, S. S.; Myers, B. R.
10.1101/2024.10.31.621410 — biochemistry — Posted on 2024-11-01
5073 N-Aldehyde-Modified Phosphatidylethanolamines generated by lipid peroxidation are robust substrates of N-Acyl Phosphatidylethanolamine Phospholipase D
Fadaei, R.; Bernstein, A. C.; Jenkins, A. N.; Pickens, A. G.; Zarrow, J. E.; Alli-oluwafuyi, A.-m. O.; Tallman, K. A.; Davies, S. S.
10.1101/2024.10.30.621135 — biochemistry — Posted on 2024-11-01
5074 High throughput single-cell proteomics of in-vivo cells
Karagach, S.; Smollich, J.; Atrakchi, O.; Mohan, V.; Geiger, T.
10.1101/2024.11.01.621461 — biochemistry — Posted on 2024-11-01
5075 EasyAb: A High-Throughput Workflow for Antibody-Based PTM Peptide Enrichment Method Coupled to Mass Spectrometry
Jayavelu, A. K.; Mann, M.; Krahmer, N.; Pfluger, P. T.; Schriever, S. C.; Schwarzer, C.; Liu, J. J.
10.1101/2024.10.29.620939 — biochemistry — Posted on 2024-11-01
5076 New Insights Into The Melanin Structure Of Lomentospora prolificans
Liporagi Lopes, L.; Chrissian, C.; Kacirani, A.; Camacho, E.; Stark, R. E.; Casadevall, A.
10.1101/2024.11.01.621558 — biochemistry — Posted on 2024-11-01
5077 Streptococcus Phage Genomes Reveal Extensive Diversity, New Taxonomic Insights, and Novel Endolysin-Derived Antimicrobial Peptides
Mondal, S. I.; Karim, D.; Rolin, M. H.; Jewel, N. A.; Hoque, H.; Buttimer, C.; Rahman, M. M.; Azad, A. K.; Akter, A.
10.1101/2024.10.31.621281 — genomics — Posted on 2024-11-01
5079 Replisome passage through the cohesin ring
Glaser, S.; Molodtsov, M. I.; Diffley, J. F.; Uhlmann, F.
10.1101/2024.10.30.621121 — molecular biology — Posted on 2024-11-01
5080 The short conserved region-2 of LARP4 interacts with ribosome-associated RACK1 and promotes translation
Ranjan, A.; Mattijssen, S.; Charlly, N.; Cruz Gallardo, I.; Pitman, L. F.; Coleman, J. C.; Conte, M. R.; Maraia, R. J.
10.1101/2024.11.01.621267 — molecular biology — Posted on 2024-11-01
5081 Alternative splicing modulates chromatin interactome and phase separation of the RIF1 C-terminal domain
Koo, A. S.-H.; Jia, W.; Kim, S. H.; Scalf, M.; Boos, C. E.; Chen, Y.; Wang, D.; Voter, A. F.; Bajaj, A.; Smith, L. M.; Keck, J. L.; Bakkenist, C. J.; Guo, L.; Tibbetts, R. S.
10.1101/2024.10.29.619708 — molecular biology — Posted on 2024-11-01
5084 Nanophysiology Approach Revealed Diversity in Calcium Microdomains in Zebrafish Retinal Bipolar Ribbon Synapses
Rameshkumar, N.; Shrestha, A. P.; Boff, J. M.; Hoon, M.; Matveev, V.; Zenisek, D.; Vaithianathan, T.
10.1101/2024.11.01.617078 — neuroscience — Posted on 2024-11-01
5085 Chitosan nanocapsules with Alstonia boonei extract modulate the immune system in Wistar rats
Nyuyfoni, G. F.; EYA ANE MEVA, F.; Kuissi, C. R. N.; Bamal, H.-D.; Fannang, S. V.; Beglau, T. H. Y.; Fetzer, M. N. A.; Ntoumba, A. A.; Nguemfo, E. L.; Fokou, J. B. H.; Djuidje, A. G.; Kojap, A. K.; Djimefo, A. K. T.; Njiemou, A. F. T.; Evouna, D. I. M.; Dongmo, A. B.; Gbambie, A. P.; Janiak, C.
10.1101/2024.10.30.621048 — pharmacology and toxicology — Posted on 2024-11-01
5086 Spatial and temporal signatures of cell competition revealed by K-function analysis
Day, N.; Michalowska, J.; Kelkar, M.; Vallardi, G.; Charras, G.; Lowe, A. R.
10.1101/2024.10.29.620688 — biophysics — Posted on 2024-11-01
5087 Single cells can resolve graded stimuli
Kramar, M.; Hahn, L.; Walczak, A. M.; Mora, T.; Coppey, M.
10.1101/2024.10.29.620645 — biophysics — Posted on 2024-11-01
5088 Vimentin molecular linkages with nesprin-3 enhance nuclear deformation by cell geometric constraints
Swoger, M.; Tri Ho Thanh, M.; Byfield, F. J.; Dam, V. B.; Williamson, J.; Frank, B.; Hehnly, H.; Conway, D.; Patteson, A. E.
10.1101/2024.10.29.621001 — biophysics — Posted on 2024-11-01
5089 Learning Binding Affinities via Fine-tuning of Protein and Ligand Language Models
Gorantla, R.; Gema, A. P.; Yang, I. X.; Serrano-Morras, A.; Suutari, B.; Jimenez, J. J.; Mey, A. S. J. S.
10.1101/2024.11.01.621495 — bioinformatics — Posted on 2024-11-01
5091 Altered renal vascular patterning reduces ischemic kidney injury and limits vascular loss associated with aging
McLarnon, S. R.; Honeycutt, S. E.; N'Guetta, P.-E. Y.; Xiong, Y.; Li, X.; Abe, K.; Kitai, H.; Souma, T.; O'Brien, L.
10.1101/2024.10.29.620969 — cell biology — Posted on 2024-11-01
5092 Tenascin-C from the tissue microenvironment promotes muscle stem cell self-renewal through Annexin A2
Loreti, M.; Cecchini, A.; Kaufman, C. D.; Stamenkovic, C.; Renero, A.; Nicoletti, C.; Kervadec-Badillo, A.; Guarnaccia, G.; Mayer, D. K.; COLAS, A.; Puri, P. L.; Sacco, A.
10.1101/2024.10.29.620732 — cell biology — Posted on 2024-11-01
5096 Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake
Myers, J. W.; Park, W. Y.; Eddie, A. M.; Shinde, A. B.; Prasad, P.; Murphy, A. C.; Leonard, M. Z.; Pinette, J. A.; Rampy, J. J.; Montufar, C.; Shaikh, Z.; Hickman, T. T.; Reynolds, G. N.; Winn, N. C.; Lantier, L.; Peck, S. H.; Coate, K. C.; Stein, R. W.; Carrasco, N.; Calipari, E. S.; McReynolds, M. R.; Zaganjor, E.
10.1101/2024.10.28.620705 — physiology — Posted on 2024-11-01
5099 Biofunctional coating of synthetic magnetic nanoparticles enables magnetogenetic control of protein functions inside cells
Kappen, M.; Gemperle, J.; Secret, E.; Flesch, J.; Caswell, P. T.; Coppey, M.; Menager, C.; Lisse, D.; Piehler, J.
10.1101/2024.10.31.621314 — biophysics — Posted on 2024-11-01
5100 Genome-wide investigation of outer membrane protein families under mosaic evolution in Escherichia coli
Cao, X.; Cao, C.; Chen, Z.; Li, J.; Zheng, Y.; Wu, J.; Li, Z.; Hu, Y.; Hao, G.; Zhu, G.; Köster, W.; White, A. P.; Wang, Y.
10.1101/2024.10.30.621157 — microbiology — Posted on 2024-11-01
5101 A lipid transport Mla Pqi Chimeric system is essential for Brucella abortus survival in macrophages
Lannoy, A.; Ronneau, A.; Fernandez Garcia, M.; Dieu, M.; Renard, P.; Garcia, A.; Conde, R.; De Bolle, X.
10.1101/2024.10.31.621289 — microbiology — Posted on 2024-11-01
5103 Cell polarity control by an unconventional G-protein complex in bacteria
Mignot, T.; Dinet, C.; Kreuzer, C.; Byrne, D.; Lhospice, S.; Herrou, J.; Durbesson, F.; Vincentelli, R.; Michelot, A.
10.1101/2024.10.31.621274 — biochemistry — Posted on 2024-11-01
5104 Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis.
Outla, Z.; Oyman-Eyrilmez, G.; Korelova, K.; Prechova, M.; Frick, L.; Sarnova, L.; Bisht, P.; Novotna, P.; Kosla, J.; Bortel, P.; Borutzki, Y.; Bileck, A.; Gerner, C.; Rahbari, M.; Rahbari, N.; Birgin, E.; Kvasnicova, B.; Galisova, A.; Sulkova, K.; Bauer, A.; Jobe, N.; Tolde, O.; Sticova, E.; Rosel, D.; O Connor, T.; Otahal, M.; Jirak, D.; Heikenwalder, M.; Wiche, G.; Meier-Menches, S. M.; Gregor, M.
10.1101/2024.08.02.606331 — cancer biology — Posted on 2024-11-01
5105 Long term trend and short-term dynamics of a willow grouse population
Willebrand, T.; Hornell-Willebrand, M.; Brittas, R.; Kleiven, E.
10.1101/2023.05.03.539219 — ecology — Posted on 2024-11-01
5106 Automated plankton monitoring suggests a key role of microzooplankton and temperature for predicting dynamics of phytoplankton size classes
Merkli, S.; Merz, E.; Reyes, M.; Ntetsika, P.; Dennis, S.; Isles, P. D. F.; Kyathanahally, S.; Baity-Jesi, M.; To, S.-W.; Merico, A.; Pomati, F.
10.1101/2024.02.23.581723 — ecology — Posted on 2024-11-01
5108 Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense
Han, W.-H.; Zhang, F.-B.; Ji, S.-X.; Liang, K.-L.; Wang, J.-X.; Fan, X.-P.; Liu, S.-S.; Wang, X.-W.
10.1101/2024.10.23.619823 — plant biology — Posted on 2024-11-01
5110 High-resolution Molecular Dynamics Simulations of the Pyruvate Kinase Muscle Isoform 1 and 2 (PKM1/2)
Delobelle, Q.; Jaffrelot-Inizan, T.; Adjoua, O. P.; Lagardere, L.; Celerse, F.; Marechal, V.; Piquemal, J.-P.
10.1101/2024.01.07.574528 — biophysics — Posted on 2024-11-01
5114 Metabolic Control of Glycosylation Forms for Establishing Glycan-Dependent Protein Interaction Networks
Liu, X.; Yi, L.; Lin, Z.; Chen, S.; Wang, S.; Sheng, Y.; Lebrilla, C. B.; Garcia, B. A.; Xie, Y.
10.1101/2024.10.30.621210 — biochemistry — Posted on 2024-11-01
5116 Defective glycosylation and ELFN1 binding of mGluR6 congenital stationary night blindness mutants
Pindwarawala, M.; Abid, F. A. K.; Lee, J.; Miller, M. L.; Noppers, J. S.; Rideout, A. P.; Agosto, M. A.
10.1101/2024.10.28.620767 — cell biology — Posted on 2024-11-01
5119 A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein
Abu-Shmais, A. A.; Guo, L.; Khalil, A. M.; Miller, R. J.; Janke, A. K.; Vukovich, M. J.; Bass, L. E.; Suresh, Y. P.; Rush, S. A.; Wolters, R. M.; Kose, N.; Carnahan, R. H.; Crowe, J. E.; Bonami, R. H.; Mousa, J. J.; McLellan, J. S.; Georgiev, I. S.
10.1101/2024.10.31.621295 — immunology — Posted on 2024-11-01
5120 Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia
Twedell, E. L.; Bair-Marshall, C. J.; Girasole, A. E.; Scaria, L. K.; Sridhar, S.; Nelson, A. B.
10.1101/2024.10.11.617939 — neuroscience — Posted on 2024-11-01
5123 Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations.
Kumawat, A.; Tavazzani, E.; Lentini, G.; Trancuccio, A.; Kukavica, D.; Denegri, M.; Priori, S. G.; Camilloni, C.
10.1101/2024.03.13.584147 — biophysics — Posted on 2024-11-01
5126 Entropy Changes in Water Networks Promote Protein Denaturation
Wang, Y.; Liu, J.; Peters, M. M.; Ishii, R.; Wang, D.; Chowdhury, S.; Parker, K. K.; Shakhnovich, E. I.
10.1101/2024.06.12.598657 — biophysics — Posted on 2024-11-01
5127 Transmembrane domains of H1 and H3 hemagglutinin contribute to membrane fusion in a different manner
Borkowska, P.; Kubiszewski-Jakubiak, S.; Bykowski, M.; Kowalewska, L.; Michalski, M.; Setny, P.; Worch, R.
10.1101/2024.10.31.621245 — biophysics — Posted on 2024-11-01
5129 Triple labeling resolves a GPCR intermediate state by 3-color single molecule FRET
Bonhomme, L.; Bilgen, E.; Clerte, C.; Pin, J.-P.; Rondard, P.; Margeat, E.; Lamb, D. C.; Quast, R. B.
10.1101/2024.10.31.621373 — biophysics — Posted on 2024-11-01
5130 Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing
Robinson, J. W.; Bechard, A. T.; Evans, M. R.; Mosuro, K.; Isaacson, J. R.; Pillay, S.; Lin, D. S.; Sahota, A.; de Belle, J. N.; Robinson, G. I.; Simon, A. F.
10.1101/2024.10.28.620699 — animal behavior and cognition — Posted on 2024-11-01
5131 Screening great ape museum specimens for DNA viruses
Haemmerle, M.; Guellil, M.; Trgovec-Greif, L.; Cheronet, O.; Sawyer, S.; Ruiz-Gartzia, I.; Lizano, E.; Rymbekova, A.; Gelabert, P.; Bernardi, P.; Han, S.; Rattei, T.; Schuenemann, V. J.; Marques-Bonet, T.; Guschanski, K.; Calvignac-Spencer, S.; Pinhasi, R.; Kuhlwilm, M.
10.1101/2024.04.25.591107 — genomics — Posted on 2024-11-01
5134 The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide
Rice, M. C.; Imun, M.; Jung, S. W.; Park, C. Y.; Kim, J. S.; Lai, R. W.; Barr, C. R.; Son, J. M.; Tor, K.; Kim, E.; Lu, R. J.; Cohen, I.; Benayoun, B. A.; Lee, C.
10.1101/2023.03.02.530691 — immunology — Posted on 2024-11-01
5135 Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampus
Duffy, E. E.; Traunmüller, L.; Liu, H.; Sanalidou, S.; Assad, E. G.; Sun, S.; Pajarillo, N. S.; Niu, N.; Griffith, E. C.; Greenberg, M. E.
10.1101/2024.10.31.621351 — neuroscience — Posted on 2024-11-01
5139 Microdissected tumor cuboids: a microscale cancer model for large-scale testing that retains a complex tumor microenvironment
Horowitz, L. F.; Rodriguez-Mias, R. A.; Chang, M.; Zhu, S.; Gottshall, N. R.; Stepanov, I.; Stiles, C.; Yeung, M.; Nguyen, T. N.; Lockhart, E. J.; Yeung, R. S.; Villen, J.; Gujral, T. S.; Folch, A.
10.1101/2024.03.22.586189 — cancer biology — Posted on 2024-11-01
5140 Regulation of NRF2 by Phosphoinositides and Small Heat Shock Proteins
Chen, C.; Chen, M.; Wen, T.; Awasthi, P.; Carrillo, N. D.; Anderson, R. A.; Cryns, V. L.
10.1101/2023.10.26.564194 — cancer biology — Posted on 2024-11-01
5142 Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors
Williams, K. B.; Larsson, A. T.; Keller, B. J.; Chaney, K. E.; Williams, R. L.; Jubenville, T. A.; Bhunia, M. M.; Draper, G. M.; Moertel, C. L.; Ratner, N.; Largaespada, D. A.
10.1101/2024.03.25.585959 — cancer biology — Posted on 2024-11-01
5144 Ligand Identification in CryoEM and X-ray Maps Using Deep Learning
Karolczak, J.; Przybylowska, A.; Szewczyk, K.; Taisner, W.; Heumann, J. M.; Stowell, M. H. B.; Nowicki, M.; Brzezinski, D.
10.1101/2024.08.27.610022 — bioinformatics — Posted on 2024-11-01
5145 Charting spatial ligand-target activity using Renoir
Rao, N.; Kumar, T.; Pai, R.; Mishra, A.; Ginhoux, F.; Chan, J.; Sharma, A.; Zafar, H.
10.1101/2023.04.14.536833 — bioinformatics — Posted on 2024-11-01
5147 Predicted constrained accessible regions mark regulatory elements and causal variants
Tomizuka, K.; Koido, M.; Suzuki, A.; Yoshino, S.; Tanaka, N.; Ishikawa, Y.; Liu, X.; Koyama, S.; Ishigaki, K.; Murakawa, Y.; Immune transcript/enhancer consortium (ITEC), ; Yamamoto, K.; Terao, C.
10.1101/2024.10.31.621195 — genetics — Posted on 2024-11-01
5149 Distinct T cell chromatin landscapes in scleroderma subtypes
Dou, D. R.; Zhao, Y.; Abe, B.; Li, R.; Zaba, L. C.; Aren, K.; Carns, M.; Chung, L. S.; Hinchcliff, M.; Chang, H. Y.
10.1101/2021.01.10.426131 — immunology — Posted on 2024-11-01
5151 Thalamic integration of basal ganglia and cerebellar circuits during motor learning
Roth, R. H.; Muniak, M. A.; Huang, C. J.; Hwang, F.-J.; Sun, Y.; Min, C.; Mao, T.; Ding, J. B.
10.1101/2024.10.31.621388 — neuroscience — Posted on 2024-11-01