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Archive, 2024-03

2 The critical role of isomiRs in accurate differential expression analysis of miRNA-seq data
Schmauch, E.; Attia, Y.; Laitinen, P.; Turunen, T. A.; Bartos, P.; Vaananen, M.-A.; Malm, T.; Tavi, P.; Kellis, M.; Kaikkonen, M. U.; Linna-Kuosmanen, S.
10.1101/2024.03.28.587190 — bioinformatics — Posted on 2024-03-31
5 Baseline microbiome composition impacts resilience to and recovery following antibiotics
Chen, C.-Y.; Loeber, U.; Bartolomaeus, H.; Maier, L.; Muller, D. N.; Wilck, N.; Jarquin-Diaz, V. H.; Forslund-Startceva, S. K.
10.1101/2024.03.31.587491 — microbiology — Posted on 2024-03-31
9 Maternal Aggression Driven by the Transient Mobilization of a Dormant Hormone-Sensitive Circuit
Stagkourakis, S.; Williams, P.; Spigolon, G.; Khanal, S.; Ziegler, K.; Heikkinen, L.; Fisone, G.; Broberger, C.
10.1101/2023.02.02.526862 — neuroscience — Posted on 2024-03-31
10 A brain-to-text framework of decoding natural tonal sentences
Zhang, D.; Wang, Z.; Qian, Y.; Zhao, Z.; Liu, Y.; Hao, X.; Li, W.; Lu, S.; Zhu, H.; Chen, L.; Xu, K.; Li, Y.; Lu, J.
10.1101/2024.03.16.585337 — neuroscience — Posted on 2024-03-31
15 Nucleic Acid Aptamers Protect Against Lead (Pb(II)) Toxicity
Anwar, A.; Ramis De Ayreflor Reyes, S.; John, A. A.; Breiling, E.; O'Connor, A. M.; Reis, S.; Shim, J.-H.; Shah, A. A.; Srinivasan, J.; Farny, N. G.
10.1101/2024.03.28.587288 — pharmacology and toxicology — Posted on 2024-03-31
16 Integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits.
Okamoto, J.; Yin, X.; Ryan, B.; Chiou, J.; Luca, F.; Pique-Regi, R.; Im, H. K.; Morrison, J.; Burant, C.; Fauman, E.; Laakso, M.; Boehnke, M.; Wen, X.
10.1101/2024.03.28.587202 — bioinformatics — Posted on 2024-03-31
17 moPepGen: Rapid and Comprehensive Proteoform Identification
Zhu, C.; Liu, L. Y.; Yamaguchi, T. N.; Zhu, H.; Hugh-White, R.; Livingstone, J.; Patel, Y.; Kislinger, T.; Boutros, P. C.
10.1101/2024.03.28.587261 — bioinformatics — Posted on 2024-03-31
20 Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry
Darula, Z.; McCabe, M. C.; Barrett, A.; Schmitt, L. R.; Maslanka, M. D.; Saviola, A. J.; Orgel, J.; Burlingame, A.; Staab-Weijnitz, C. A.; Stenmark, K.; Weaver, V.; Chalkley, R. J.; Hansen, K. C.
10.1101/2024.03.31.587441 — biochemistry — Posted on 2024-03-31
21 Long-Read Structural and Epigenetic Profiling of a Kidney Tumor-matched Sample with Nanopore Sequencing and Optical Genome Mapping
Margalit, S.; Tulpova, Z.; Detinis Zur, T.; Michaeli, Y.; Deek, J.; Nifker, G.; Haldar, R.; Gnatek, Y.; Omer, D.; Dekel, B.; Grunwald, A.; Ebenstein, Y.
10.1101/2024.03.31.587463 — genomics — Posted on 2024-03-31
25 Essential genes for Haemophilus parainfluenzae survival and biofilm growth
de Palma, T. H.; Powers, C.; McPartland, M. J.; Welch, J. L. M.; Ramsey, M. M.
10.1101/2024.03.31.587483 — microbiology — Posted on 2024-03-31
27 TET2 regulates early and late transitions in exhausted CD8+ T-cell differentiation and limits CAR T-cell function
Dimitri, A. J.; Baxter, A. E.; Chen, G. M.; Hopkins, C. R.; Rouin, G. T.; Huang, H.; Kong, W.; Holliday, C. H.; Wiebking, V.; Bartoszek, R.; Drury, S.; Dalton, K.; Koucky, O. M.; Chen, Z.; Giles, J. R.; Jung, I.-Y.; O'Connor, R.; Collins, S.; Everett, J. K.; Amses, K.; Sherrill-Mix, S.; Chandra, A.; Goldman, N.; Vahedi, G.; Jadlowsky, J. K.; Young, R. M.; Melenhorst, J. J.; Maude, S. L.; Levine, B. L.; Frey, N. V.; Berger, S. L.; Grupp, S. A.; Porter, D. L.; Herbst, F.; Porteus, M. H.; Bushman, F. D.; Weber, E. W.; Wherry, E. J.; Jordan, M. S.; Fraietta, J. A.
10.1101/2024.03.29.587004 — immunology — Posted on 2024-03-31
28 IL-10 dependent adaptation allows macrophages to adjust inflammatory responses to TLR4 stimulation history
Bongartz, H.; Bradfield, C. J.; Gross, J. L.; Fraser, I.; Nita-Lazar, A.; Meier-Schellersheim, M.
10.1101/2024.03.28.587272 — immunology — Posted on 2024-03-31
30 Dendrite injury, but not axon injury, triggers neuroprotection in Drosophila models of neurodegenerative disease.
Prange, S. E.; Bhakta, I. N.; Sysoeva, D.; Jean, G. E.-H.; Madisetti, A.; Duong, L. U.; Hwu, P. T.; Melton, J. G.; Le, H. H. N.; Thompson-Peer, K. L.
10.1101/2024.03.29.587363 — neuroscience — Posted on 2024-03-31
33 Neurofilament accumulation disrupts autophagy in giant axonal neuropathy
Paumier, J.-M.; Zewe, J.; Pergande, M. R.; Venkatesan, M.; Israeli, E.; Panja, C.; Snider, N.; Savas, J.; Opal, P.
10.1101/2024.03.29.587353 — neuroscience — Posted on 2024-03-31
39 Motion vision is tuned to maximize sensorimotor energy transfer in blowfly flight
Humbert, S.; Krapp, H. G.; Baeder, J. D.; Badrya, C.; Dawson, I. L.; Huang, J. V.; Hyslop, A.; Jung, Y. S.; Lutkus, C.; Mortimer, B.; Nagesh, I.; Ruah, C.; Walker, S. M.; Yang, Y.; Zbikowski, R.; Taylor, G. K.
10.1101/2024.03.29.587347 — neuroscience — Posted on 2024-03-31
40 Trauma Under Psychedelics: MDMA Shows Protective Effects During the Peritraumatic Period
Netzer, O.; Magal, N.; Stern, Y.; Polinsky, T.; Gross, R.; Admon, R.; Salomon, R.
10.1101/2024.03.28.587237 — neuroscience — Posted on 2024-03-31
46 Desynchronization between timers provokes transient arrest during C. elegans development
Romero-Exposito, F. J.; Moreno-Rivero, A.; Munoz-Barrera, M.; Garcia-Sanchez, S.; Rodriguez-Peris, F.; Gritti, N.; Sartor, F.; Merrow, M.; van Zon, J. S.; Mata-Cabana, A.; Olmedo, M.
10.1101/2024.03.31.587169 — developmental biology — Posted on 2024-03-31
50 An Open Resource: MR and light sheet microscopy stereotaxic atlas of the mouse brain
Mansour, H.; Azrak, R.; Cook, J. J.; Hornburg, K. J.; Qi, Y.; Tian, Y.; Williams, R. W.; Yeh, F.-C.; White, L. E.; Johnson, G. A.
10.1101/2024.03.28.587246 — neuroscience — Posted on 2024-03-31
52 TDP43 proteinopathy exhibits disease, tissue, and context-specific cryptic splicing signatures
Newton, D. F.; Yang, R.; Gutierrez, J.; Hofmann, J. W.; Yeh, F. L.; Biever, A.; Friedman, B. A.
10.1101/2024.03.29.587244 — neuroscience — Posted on 2024-03-31
53 Synaptic-dependent developmental dysconnectivity in 22q11.2 deletion syndrome
Alvino, F.-G.; Gini, S.; Minetti, A.; Pagani, M.; Sastre-Yague, D.; Barsotti, N.; De Guzman, E.; Schleifer, C.; Stuefer, A.; Kushan, L.; Montani, C.; Galbusera, A.; Papaleo, F.; Lombardo, M.-V.; Pasqualetti, M.; Bearden, C. E.; Gozzi, A.
10.1101/2024.03.29.587339 — neuroscience — Posted on 2024-03-31
54 fMROI: a simple and adaptable toolbox for easy region-of-interest creation
Peres, A. S. C.; Valerio, D.; Vaz, I. S.; Mahdiani, M.; Walbrin, J.; Almeida, J.
10.1101/2024.03.29.587330 — neuroscience — Posted on 2024-03-31
55 The subcommissural organ regulates brain development via secreted peptides
Zhang, T.; Ai, D.; Wei, P.; Xu, Y.; Bi, Z.; Ma, F.; Li, F.; Chen, X.-j.; Zhang, Z.; Zou, X.; Guo, Z.; Zhao, Y.; Li, J.-L.; Ye, M.; Feng, Z.; Zhang, X.; Zheng, L.; Yu, J.; Li, C.; Tu, T.; Zeng, H.; Lei, J.; Zhang, H.; Hong, T.; Zhang, L.; Luo, B.; Li, Z.; Xing, C.; Jia, C.; Li, L.; Sun, W.; Ge, W.-p.
10.1101/2024.03.30.587415 — neuroscience — Posted on 2024-03-31
56 Open-source, high performance miniature multiphoton microscopy systems for freely behaving animals
Madruga, B. A.; Dorian, C. C.; Sehgal, M.; Silva, A. J.; Shtrahman, M.; Aharoni, D.; Golshani, P.
10.1101/2024.03.29.586663 — neuroscience — Posted on 2024-03-31
57 Shape dynamics and migration of branched cells on complex networks
Liu, J.; Boix-Campos, J.; Ron, J. E.; Kux, J. M.; Gov, N.; Saez, P. J.
10.1101/2024.03.29.585638 — biophysics — Posted on 2024-03-31
58 CDHu40: a novel marker gene set of neuroendocrine prostate cancer (NEPC)
Liu, S.; Nam, H. S.; Zeng, Z.; Deng, X.; Pashaei, E.; Zang, Y.; Yang, L.; Li, C.; Huang, J.; Wendt, M. K.; Lu, X.; Huang, R.; Wan, J.
10.1101/2024.03.28.587205 — bioinformatics — Posted on 2024-03-31
59 Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking
el Azhar, Y.; Schulthess, P.; van Oostrom, M. J.; Meijer, W. H. M.; Thomas, W. M.; Bauer, M.; Sonnen, K. F.
10.1101/2024.03.30.586691 — developmental biology — Posted on 2024-03-31
62 A pangenomic perspective of the Lake Malawi cichlid radiation reveals extensive structural variation driven by transposable elements
Quah, F. X.; Almeida, M. V.; Blumer, M.; Yuan, C. U.; Fischer, B.; See, K.; Jackson, B.; Zatta, R.; Rusuwa, B.; Turner, G. F.; Santos, M. E.; Svardal, H.; Hemberg, M.; Durbin, R.; Miska, E.
10.1101/2024.03.28.587230 — evolutionary biology — Posted on 2024-03-31
63 A Synergistic Desmin-SPARC Axis Regulates Cardiac Stem Cell Differentiation and Promotes Cardiomyogenesis through Autocrine Regulation
Leitner, L.; Schultheis, M.; Hofstetter, F.; Rudolf, C.; Kizner, V.; Fiedler, K.; Konrad, M.-T.; Hoebaus, J.; Genini, M.; Kober, J.; Ableitner, E.; Gmaschitz, T.; Walder, D.; Weitzer, G.
10.1101/2024.03.28.587296 — developmental biology — Posted on 2024-03-31
64 Enhanced NK cell proficiency in solid tumors through antigen-specific memory via NKG2C/A-HLA-E/ABC recruited to tumors by CXCR2
Sun, Y.; Furones, A. R.; Gultekin, O.; Khare, S.; Neo, S. Y.; Shi, W.; Galceran, L. M.; Lam, K.-P.; DasGupta, R.; Fuxe, J.; Salehi, S.; Lehti, K.; Sarhan, D.
10.1101/2024.03.28.585607 — immunology — Posted on 2024-03-31
65 Type I interferon drives a cellular state inert to TCR-stimulation and could impede effective T-cell differentiation in cancer
Corvino, D.; Batstone, M.; Hughes, B. G. M.; Kempchen, T.; Ng, S. S.; Salim, N.; Schneppenheim, F.; Rommel, D.; Kumar, A.; Pearson, S.; Madore, J.; Koufariotis, L. T.; Steinheuer, L. M.; Pathirana, D.; Thurley, K.; Hoelzel, M.; Borcherding, N.; Braun, M.; Bald, T.
10.1101/2024.03.28.587179 — immunology — Posted on 2024-03-31
66 The metabolic cofactor Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling
Jones, A. E.; Rios, A.; Ibrahimovic, N.; Chavez, C.; Bayley, N. A.; Ball, A. B.; Hsieh, W. Y.; Sammarco, A.; Bianchi, A. R.; Cortez, A. A.; Graeber, T. G.; Hoffmann, A.; Bensinger, S. J.; Divakaruni, A. S.
10.1101/2024.03.28.587096 — immunology — Posted on 2024-03-31
70 Soft skeletons transmit force with variable gearing
Ellers, O.; Ellers, K.-I.; Johnson, A. S.; Po, T.; Heydari, S.; Kanso, E.; McHenry, M. J.
10.1101/2024.03.28.587271 — zoology — Posted on 2024-03-31
72 Stacking haplotypes from the Vavilov wheat collection to accelerate breeding for multiple disease resistance
Tong, J.; Tarekegn, Z.; Alahmad, S.; Hickey, L.; Periyannan, S.; Dinglasan, E.; Hayes, B. J. A.
10.1101/2024.03.28.587294 — plant biology — Posted on 2024-03-31
73 The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle.
Prabakaran, A. D.; Chung, H.-J.; McFarland, K.; Govindarajan, T.; Soussi, F. E. A.; Durumutla, H. B.; Villa, C.; Piczer, K.; Latimer, H.; Werbrich, C.; Akinborewa, O.; Horning, R.; Quattrocelli, M.
10.1101/2024.03.28.586997 — physiology — Posted on 2024-03-31
75 Development of a Two-Leaf Photosynthetic Model Sensitive to Chlorophyll and Its Coupling with a Wheat Growth Model
Tang, Y.; Wang, J.; Hong, Y.; Guo, C.; Zheng, H.; Yao, X.; Cheng, T.; Zhu, Y.; Cao, W.; Tian, Y.
10.1101/2024.03.28.587183 — biophysics — Posted on 2024-03-31
79 Biomechanical regulation of cell shapes promotes branching morphogenesis of the ureteric bud epithelium
Kurtzeborn, K.; Iaroshenko, V.; Zarybnicky, T.; Koivula, J.; Anttonen, H. S.; Bridgewater, D.; Krishnan, R.; Chen, P.; Kuure, S.
10.1101/2024.03.28.585666 — developmental biology — Posted on 2024-03-31
80 Positional information modulates transient regeneration-activated cell states during vertebrate appendage regeneration.
Ortega Granillo, A.; Zamora, D.; Schnittker, R. R.; Scott, A. R.; Russell, J.; Brewster, C. E.; Ross, E. J.; Acheampong, D. A.; Ferro, K.; Morrison, J. A.; Rubinstein, B. Y.; Perera, A. G.; Wei, W.; Sanchez Alvarado, A.
10.1101/2024.03.28.587250 — developmental biology — Posted on 2024-03-31
81 A brain-to-text framework of decoding natural tonal sentences
Zhang, D.; Wang, Z.; Qian, Y.; Zhao, Z.; Liu, Y.; Hao, X.; Li, W.; Lu, S.; Zhu, H.; Chen, L.; Xu, K.; Li, Y.; Lu, J.
10.1101/2024.03.16.585337 — neuroscience — Posted on 2024-03-31
82 Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres
Poulopoulos, A.; Davis, P.; Brandenburg, C.; Itoh, Y.; Galazo, M. J.; Greig, L. C.; Romanowski, A. J.; Budnik, B.; Macklis, J. D.
10.1101/2024.03.28.587108 — neuroscience — Posted on 2024-03-31
84 GABAergic synapses between auditory efferent neurons and type II spiral ganglion afferent neurons in the mouse cochlea
Bachman, J. L.; Kitcher, S. R.; Vattino, L. G.; Beaulac, H. J.; Chaves, M. G.; Hernandez Rivera, I.; Katz, E.; Wedemeyer, C.; Weisz, C. J. C.
10.1101/2024.03.28.587185 — neuroscience — Posted on 2024-03-31
87 Life history traits influence the dynamics of genetic diversityin a refugium population undergoing expansion andcontraction
Vishwakarma, R.; Sgarlata, G. M.; Soriano-Panos, D.; Rasteiro, R.; Maie, T.; Paixao, T.; Tournebize, R.; Chikhi, L.
10.1101/2024.03.28.586951 — evolutionary biology — Posted on 2024-03-31
88 Imaging of existing and newly translated proteins elucidates mechanisms of sarcomere turnover
Douvdevany, G.; Erlich, I.; Haimovich-Caspi, L.; Mashiah, T.; Prondzynski, M.; Pricolo, M. R.; Alegre-Cebollada, J.; Linke, W. A.; Carrier, L.; Kehat, I.
10.1101/2023.08.31.555653 — cell biology — Posted on 2024-03-31
89 Ribosomal Protein SA (RPSA) is required for localized translation and sarcomere maintenance in mice
Haddad, R.; Sadeh, O.; Ziv, T.; Erlich, I.; Haimovich-Caspi, L.; Shemesh, A.; van der Velden, J.; Kehat, I.
10.1101/2023.07.26.550187 — cell biology — Posted on 2024-03-31
90 Metabolic modeling reveals the aging-associated decline of host-microbiome metabolic interactions in mice
Best, L.; Dost, T.; Esser, D.; Flor, S.; Haase, M.; Kadibalban, A. S.; Marinos, G.; Walker, A.; Zimmermann, J.; Simon, R.; Schmidt, S.; Taubenheim, J.; Kunzel, S.; Hasler, R.; Groth, M.; Waschina, S.; Witte, O. W.; Schmitt-Kopplin, P.; Baines, J. F.; Frahm, C.; Kaleta, C.
10.1101/2024.03.28.587009 — systems biology — Posted on 2024-03-31
95 Learning and actioning general principles of cancer cell drug sensitivity
Carli, F.; Di Chiaro, P.; Morelli, M.; Arora, C.; Bisceglia, L.; De Oliveira Rosa, N.; Cortesi, A.; Franceschi, S.; Lessi, F.; Di Stefano, A. L.; Santonocito, O. S.; Pasqualetti, F.; Aretini, P.; Miglionico, P.; Diaferia, G. R.; Giannotti, F.; Lio, P.; Duran-Frigola, M.; Mazzanti, C. M.; Natoli, G.; Raimondi, F.
10.1101/2024.03.28.586783 — bioinformatics — Posted on 2024-03-30
99 Single-cell genomics and regulatory networks for 388 human brains
Emani, P. S.; Liu, J. J.; Clarke, D.; Jensen, M.; Warrell, J.; Gupta, C.; Meng, R.; Lee, C. Y.; Xu, S.; Dursun, C.; Lou, S.; Chen, Y.; Chu, Z.; Galeev, T.; Hwang, A.; Li, Y.; Ni, P.; Zhou, X.; PsychENCODE Consortium, ; Bakken, T. E.; Bendl, J.; Bicks, L.; Chatterjee, T.; Cheng, L.; Cheng, Y.; Dai, Y.; Duan, Z.; Flaherty, M.; Fullard, J. F.; Gancz, M.; Garrido-Martin, D.; Gaynor-Gillett, S.; Grundman, J.; Hawken, N.; Henry, E.; Hoffman, G. E.; Huang, A.; Jiang, Y.; Jin, T.; Jorstad, N. L.; Kawaguchi, R.; Khullar, S.; Liu, J.; Liu, J.; Liu, S.; Ma, S.; Margolis, M.; Mazariegos, S.; Moore, J.; M
10.1101/2024.03.18.585576 — genomics — Posted on 2024-03-30
101 Diel Partitioning in Microbial Phosphorus Acquisition in the Sargasso Sea
Muratore, D. J.; Gilbert, N. E.; LeCleir, G. R.; Wilhelm, S.; Weitz, J. S.
10.1101/2024.03.28.587236 — ecology — Posted on 2024-03-30
107 Phenylketonuria: modelling cerebral amino acid and neurotransmitter metabolism
Wegrzyn, A. B.; van Vliet, D.; van Eunen, K.; Heiner-Fokkema, M. R.; van der Zee, E. A.; van Spronsen, F.; Bakker, B. M.
10.1101/2024.01.05.574352 — systems biology — Posted on 2024-03-30
108 Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma
Dantzer, C.; Vache, J.; Brunel, A.; Mahouche, I.; Raymond, A.-A.; Dupuy, J.-W.; Petrel, M.; Bioulac-Sage, P.; Perrais, D.; Dugot-Senant, N.; Verdier-Sage, M.; Bessette, B.; Billottet, C.; Moreau, V.
10.1101/2023.10.24.563805 — cancer biology — Posted on 2024-03-30
111 Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC
Su, Q.; Zhang, J.; Lin, W.; Zhang, J.-f.; Newton, A. C.; Mehta, S.; Yang, J.; Zhang, J.
10.1101/2024.03.29.587373 — bioengineering — Posted on 2024-03-30
113 WHOLE GENOME TARGETED ENRICHMENT AND SEQUENCING OF HUMAN-INFECTING CRYPTOSPORIDIUM spp.
Bayona Vasquez, N. J.; Sullivan, A. H.; Beaudry, M. S.; Khan, A.; de Paula Baptista, R.; Petersen, K. N.; Bhuiyan, M. I. U.; Brunelle, B.; Robinson, G.; Chalmers, R. M.; Alves-Ferreira, E. V.; Grigg, M. E.; Kissinger, J. C.; Glenn, T. C.
10.1101/2024.03.29.586458 — genomics — Posted on 2024-03-30
115 Long term co-circulation of multiple arboviruses in southeast Australia revealed by xeno-monitoring of mosquitoes and metatranscriptomics
Vieira, C. J. S. P.; Onn, M. B.; Shivas, M. A.; Shearman, D.; Darbro, J. M.; Graham, M.; Freitas, L.; van den Hurk, A. F.; Frentiu, F. F.; Wallau, G. L.; Devine, G. J.
10.1101/2024.03.29.587110 — genomics — Posted on 2024-03-30
116 CRISPR/Cas9 gene editing in Drosophila via visual selection in a summer classroom
Kockel, L.; Zhang, V.; Wang, J.; Gulick, C.; Laws, M. E.; Rajan, A.; Lantz, N.; Asgarova, A.; Dai, L.; Garcia, K.; Kim, C.; Li, M.; Ordonez-Acosta, P.; Peng, D.; Shull, H.; Tse, L.; Wang, Y.; Yu, W.; Zhou, Z.; Rankin, A.; Park, S.; Kim, S. K.
10.1101/2024.03.28.587232 — genetics — Posted on 2024-03-30
120 Million years old recombination suppression and balancing selection in a region linked to the mating-type locus in the invasive chestnut blight fungal pathogen Cryphonectria parasitica
Hartmann, F. E.; Rodriguez de la Vega, R. C.; Rougemont, Q.; Demene, A.; Badet, T.; Croll, D.; Labat, A.; Prospero, S.; Snirc, A.; Stauber, L.; Dutech, C.; Giraud, T.
10.1101/2024.03.29.587348 — evolutionary biology — Posted on 2024-03-30
121 Timing of standard chow exposure determines the variability of mouse phenotypic outcomes and gut microbiota profile
Knuth, M. M.; Campos, C. V.; Smith, K.; Hutchins, E. K.; Lewis, S.; York, M.; Coghill, L. M.; Franklin, C.; MacFarlane, A.; Ericsson, A. C.; Magnuson, T.; Ideraabdullah, F.
10.1101/2024.03.28.587032 — developmental biology — Posted on 2024-03-30
123 GTRpmix: A linked general-time reversible model for profile mixture models
Banos, H.; Wong, T. K. F.; Daneau, J.; Susko, E.; Minh, B. Q.; Lanfear, R.; Brown, M. W.; Eme, L.; Roger, A. J.
10.1101/2024.03.29.587376 — molecular biology — Posted on 2024-03-30
124 Identification of a proteolysis regulator for an essential enzyme in Mycobacterium tuberculosis
Kahne, S. C.; Yoo, J. H.; Chen, J.; Nakedi, K.; Iyer, L. M.; Putzel, G.; Samhadaneh, N. M.; Pironti, A.; Aravind, L.; Ekiert, D. C.; Bhabha, G.; Rhee, K. Y.; Darwin, K. H.
10.1101/2024.03.29.587195 — microbiology — Posted on 2024-03-30
125 Prophages express a type IV pilus component to provide anti-phage defence
Sztanko, K. M.; Javorcik, P. N.; Fitzpatrick, A. D.; Lenskaia, T.; Maxwell, K. L.; Davidson, A. R.
10.1101/2024.03.29.587342 — microbiology — Posted on 2024-03-30
126 A comprehensive two-hybrid analysis to explore the L. pneumophila effector-effector interactome
O'Connor Mount, H.; Urbanus, M. L.; Sheykhkarimli, D.; Cote, A. G.; Laval, F.; Coppin, G.; Kishore, N.; Li, R.; Spirohn-Fitzgerald, K.; Petersen, M. O.; Knapp, J. J.; Kim, D.-K.; Twizere, J.-C.; Calderwood, M. A.; Vidal, M.; Roth, F. P.; Ensminger, A. W.
10.1101/2024.03.29.587239 — microbiology — Posted on 2024-03-30
128 GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice
Takahashi, K.; Rensing, N. R.; Eultgen, E. M.; Wang, S. H.; Nelvagal, H. R.; Le, S. Q.; Roberts, M. S.; Doray, B.; Han, E.; Dickson, P.; Wong, M.; Sands, M. S.; Cooper, J. D.
10.1101/2024.03.29.587276 — neuroscience — Posted on 2024-03-30
129 p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer
Luo, J.; Chen, Z.; Qiao, Y.; Tien, J. C.-Y.; Young, E.; Mannan, R.; Mahapatra, S.; He, T.; Eyunni, S.; Zhang, Y.; Zheng, Y.; Su, F.; Cao, X.; Wang, R.; Cheng, Y.; Seri, R.; George, J.; Shahine, M.; Miner, S. J.; Vaishampayan, U.; Wang, M.; Wang, S.; Parolia, A.; Chinnaiyan, A. M.
10.1101/2024.03.29.587346 — cancer biology — Posted on 2024-03-30
130 IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma
Medina, S.; Brockman, A. A.; Cross, C. E.; Hayes, M. J.; Mobley, B. C.; Mistry, A. M.; Chotai, S.; Weaver, K. D.; Thompson, R.; Chambless, L. B.; Ihrie, R. A.; Irish, J. M.
10.1101/2024.03.29.587030 — cancer biology — Posted on 2024-03-30
132 Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter
Goyal, P.; Dhanabalan, K.; Scalise, M.; Friemann, R.; Indiveri, C.; Dobson, R. C.; Vinothkumar, K. R.; Subramanian, R.
10.1101/2024.03.29.587382 — biochemistry — Posted on 2024-03-30
133 Ribonuclease Inhibitor and Angiogenin collaboratively regulate cell-type-specific global translation
Stillinovic, M.; Sarangdhar, M. A.; Andina, N.; Tardivel, A.; Greub, F.; Bombaci, G.; Ansermet, C.; Heller, M.; Keogh, A.; Keller, I.; Angelillo-Scherrer, A.; Allam, R.
10.1101/2024.03.29.586999 — biochemistry — Posted on 2024-03-30
134 Cis-vaccenic acid is a key product of stearoyl-CoA desaturase 1 and a critical oncogenic factor in prostate cancer
Scott, J. S.; Young, R. S.; Quek, L.-E.; Miller, D. C.; Evergren, E. S.; Dehairs, J.; Johnson, I. R.; Brooks, D. A.; Loda, M.; Hoy, A. J.; Blanksby, S. J.; Swinnen, J. V.; Nassar, Z. D.; Butler, L. M.
10.1101/2024.03.28.587238 — cell biology — Posted on 2024-03-30
135 Investigating endometriosis development and endometriosis-related pain over time and in relation to estrogen in a laparoscopic mouse model
Peterse, D.; Verhassel, A.; Fassbender, A.; O, D. F.; Vanhie, A.; Van Rompuy, A.-S.; Saunders, P.; Vriens, J.; D'Hooghe, T.
10.1101/2024.03.28.583957 — cell biology — Posted on 2024-03-30
136 A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival
cassano, j.; Poolsup, S.; Duran, J.; Allers, l.; Leums, M.; cheng, q.; Salemi, M.; Phinney, B.
10.1101/2024.03.29.587368 — cell biology — Posted on 2024-03-30
140 Cell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells
Gensbittel, V.; Follain, G.; Bochler, L.; Uhlmann, K.; Lefebvre, O.; Larnicol, A.; Harlepp, S.; Goswami, R.; Girardo, S.; Hyenne, V.; Mittelheisser, V.; Krater, M.; Balzani, D.; Guck, J.; Osmani, N.; Goetz, J. G.
10.1101/2024.03.28.587171 — cancer biology — Posted on 2024-03-30
141 Oncogenic Phase Transitions: How Mutant p53 Drives Amyloid Formation in p63 and p73 Liquid Droplets
Petronilho, E. C.; de Andrade, G. C. C.; de Sousa, G. d. S.; Almeida, F. P.; Mota, M. F.; Marques, M. A.; Vieira, T. C. R. G.; de Oliveira, G. A. P.; Silva, J. L.
10.1101/2024.03.28.583974 — cancer biology — Posted on 2024-03-30
146 APP and β-amyloid modulate protein aggregation and dissociation from recycling endosomal and exosomal membranes
Singh, P. J.; Verma, B.; Wells, A.; Mendes, C. C.; Dunn, D.; Chen, Y.-N.; Oh, J.; Blincowe, L.; Wainwright, M.; Fischer, R.; Fan, S.-J.; Harris, A. L.; Goberdhan, D. C.; Wilson, C.
10.1101/2024.03.28.586966 — cell biology — Posted on 2024-03-30
148 A multi-track landscape of haematopoiesis informed by cellular barcoding and agent-based modelling
Lin, D.; Zhang, S.; Schreuder, J.; Tran, J.; Metcalf, D.; Sargeant, T.; Ng, A. P.; Weber, T. S.; Naik, S.
10.1101/2024.03.28.587126 — immunology — Posted on 2024-03-30
149 Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis
Naim, G.; Romano, H.; Amidror, S.; Jessula Levy, D.; Cohen, A.; Sochen, C.; Yarden, Y.; Feng, M.; Farah, N.; Tsentsarevsky, R.; Brodie, Z.; Reich, Y.; Simon, A.; Toister, E.; Shoval, I.; Mandel, Y.; Biton, M.; Yissachar, N.
10.1101/2024.03.28.587149 — neuroscience — Posted on 2024-03-30
151 A RALF-Brassinosteroid morpho-signaling circuit regulates Arabidopsis hypocotyl cell shape
Biermann, D.; von Arx, M.; Xhelilaj, K.; Sere, D.; Stegmann, M.; Wolf, S.; Zipfel, C.; Gronnier, J.
10.1101/2024.03.28.587199 — plant biology — Posted on 2024-03-30
153 EDSpliCE, a CRISPR-Cas9 gene editing platform to rescue splicing, effectively corrects inherited retinal dystrophy-associated splicing defects
De Angeli, P.; Shliaga, S.; Flores-Tufino, A.; Roschi, E.; Spaag, S.; Stingl, K.; Kuehlewein, L.; Wissinger, B.; Kohl, S.
10.1101/2024.03.27.587013 — genomics — Posted on 2024-03-30
154 Tissue-Specific Dynamics of TCF4 Triplet Repeat Instability Revealed by Optical Genome Mapping
Zarouchlioti, C.; Efthymiou, S.; Fracchini, S.; Dominik, N.; Bhattacharyya, N.; Liu, S.; Abreu Costa, M.; Szabo, A.; Sadan, A. N.; Jun, A.; Bugiardini, E.; Houlden, H.; Cortese, A.; Skalicka, P.; Dudakova, L.; Muthusamy, K.; Cheetham, M. E.; Hardcastle, A. J.; Liskova, P.; Tuft, S. J.; Davidson, A.
10.1101/2024.03.27.587034 — genomics — Posted on 2024-03-30
156 Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community
Scarinci, G.; Ariens, J.-L.; Angelidou, G.; Schmidt, S.; Glatter, T.; Paczia, N.; Sourjik, V.
10.1101/2024.03.30.587424 — evolutionary biology — Posted on 2024-03-30
159 A Gridded Microclimate Dataset from a Sub-Arctic Biodiversity Hotspot in Finland
Niittynen, P.; Salminen, H.; Pena-Aguilera, P.; Aalto, J.; Alahuhta, J.; Luoto, M.; Maliniemi, T.; Rissanen, T.; Roslin, T.; Tukiainen, H.; Tyystjarvi, V.; Kemppinen, J.
10.1101/2024.03.30.587419 — ecology — Posted on 2024-03-30
160 Arginine methylation of the p30 C/EBPα oncoprotein regulates progenitor proliferation and myeloid differentiation
Nguyen, L. T.; Zimmermann, K.; Kowenz-Leutz, E.; Dörr, D.; Schütz, A.; Schönheit, J.; Mildner, A.; Leutz, A.
10.1101/2024.03.28.587207 — cell biology — Posted on 2024-03-30
163 Tonic dendritic GABA release by substantia nigra dopaminergic neurons
Simmons, D. V.; Ding, J.; Khakh, B.; Awatramani, R. V.; Surmeier, D. J.
10.1101/2024.03.27.586699 — neuroscience — Posted on 2024-03-30
169 Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling
Le Gac, B.; Tournissac, M.; Belzic, E.; Picaud, S.; Dusart, I.; Soula, H.; Li, D.; Charpak, S.; Cauli, B.
10.1101/2024.03.27.586974 — neuroscience — Posted on 2024-03-30
170 Large-scale RNA-seq mining reveals ciclopirox triggers TDP-43 cryptic exons
Sinha, I. R.; Sandal, P. S.; Burns, G. D.; Mallika, A. P.; Irwin, K. E.; Cruz, A. L. F.; Wang, V.; Rodriguez, J. L.; Wong, P. C.; Ling, J. P.
10.1101/2024.03.27.587011 — neuroscience — Posted on 2024-03-30
173 HPV-positive head and neck squamous cell carcinoma cells lose viability during triggered myocyte lineage differentiation
Gendreizig, S.; Martinez-Ruiz, L.; Lopez-Rodriguez, A.; Pabla, H.; Hose, L.; Brasch, F.; Busche, T.; Escames, G.; Sudhoff, H.; Scholtz, L. U.; Todt, I.; Oppel, F.
10.1101/2024.03.28.587125 — cancer biology — Posted on 2024-03-30
174 Multi-Omics Analysis Reveals the Attenuation of the Interferon Pathway as a Driver of Chemo-Refractory Ovarian Cancer
Afenteva, D.; Yu, R.; Rajavuori, A.; Salvadores, M.; Launonen, I.-M.; Lavikka, K.; Zhang, K.; Marchi, G.; Jamalzadeh, S.; Isoviita, V.-M.; Li, Y.; Micoli, G.; Erkan, E. P.; Falco, M. M.; Ungureanu, D.; Lahtinen, A.; Oikkonen, J.; Hietanen, S.; Vaharautio, A.; Sur, I.; Virtanen, A.; Farkkila, A.; Hynninen, J.; Muranen, T. A.; Taipale, J.; Hautaniemi, S.
10.1101/2024.03.28.587131 — cancer biology — Posted on 2024-03-30
175 Learning and actioning general principles of cancer cell drug sensitivity
Raimondi, F.; Di Chiaro, P.; Morelli, M.; Arora, C.; Bisceglia, L.; De Oliveira Rosa, N.; Cortesi, A.; Franceschi, S.; Lessi, F.; Di Stefano, A. L.; Santonocito, O. S.; Pasqualetti, F.; Aretini, P.; Miglionico, P.; Diaferia, G. R.; Giannotti, F.; Lio, P.; Duran-Frigola, M.; Mazzanti, C. M.; Natoli, G.; Raimondi, F.
10.1101/2024.03.28.586783 — bioinformatics — Posted on 2024-03-30
177 LeGenD: determining N-glycoprofiles using an explainable AI-leveraged model with lectin profiling
Li, H.; Peralta, A. G.; Schoffelen, S.; Hansen, A. H.; Arnsdorf, J.; Schinn, S.-M.; Skidmore, J.; Choudhury, B.; Paulchakrabarti, M.; Voldborg, B. G.; Chiang, A. W. T.; Lewis, N. E.
10.1101/2024.03.27.587044 — bioengineering — Posted on 2024-03-30
178 A novel functional gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types
Prince, C.; Bounoutas, G.; Zhou, B.; Raja, W.; Gold, I.; Pozsgai, R.; Thakker, P.; Boisvert, N.; Reardon, C.; Thurmond, S.; Ozturk, E.; Boggavarapu, R.; Springer, S.; Chahal, L.; Nogalski, M.; Ong, T.; Nawandar, D.; Wright, C.; Mackey, A.; Parsons, G.; Cabral, J.
10.1101/2024.03.27.586964 — bioengineering — Posted on 2024-03-30
184 Transposable elements as evolutionary driving force to ecological speciation in cactophilic Drosophila species
Oliveira, D. S. d.; Larue, A.; Nunes, W. V. B.; Sabot, F.; Bodelon, A.; Guerreiro, M. P. G.; Vieira, C.; Carareto, C. M.
10.1101/2024.03.27.587021 — evolutionary biology — Posted on 2024-03-30
185 Short lifespan is one's fate, long lifespan is one's achievement: lessons from Daphnia
Beam, T. C.; Bright, M. P.; Pearson, A. C.; Dua, I.; Dutta, A. K.; Smith, M. L.; Bhadra, S.; Strickler, C. N.; Salman, S.; Anderson, C. E.; Peshkin, L.; Yampolsky, L. Y.
10.1101/2024.03.30.587428 — ecology — Posted on 2024-03-30
186 Life-history adaptation under climate warming magnifies the agricultural footprint of a cosmopolitan insect pest
Burc, E.; Girard-Tercieux, C. E.; Metz, M.; Cazaux, E.; Baur, J.; Koppik, M.; Rego, A.; Hart, A.; Berger, D.
10.1101/2024.03.30.587412 — ecology — Posted on 2024-03-30
188 Uncertainty in Thermosensory Expectations Enhances an Illusion of Pain
Ehmsen, J. F.; Nikolova, N.; Christensen, D. E.; Banellis, L.; Braendholt, M.; Courtin, A. S.; Kraenge, C. E.; Mitchell, A. G.; Deolindo, C. S.; Steenkjaer, C.; Vejloe, M.; Mathys, C.; Allen, M. G.; Fardo, F.
10.1101/2024.03.27.587070 — neuroscience — Posted on 2024-03-30
189 Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes
Franco-Enzastiga, U.; Inturi, N. N.; Natarajan, K.; Mwirigi, J. M.; Mazhar, K.; Schlachetzki, J. C.; Schumacher, M.; Price, T. J.
10.1101/2024.03.27.587047 — neuroscience — Posted on 2024-03-30
191 The laminar organization of cell types in macaque cortex and its relationship to neuronal oscillations
Lichtenfeld, M. J.; Mulvey, A. G.; Nejat, H.; Xiong, Y. S.; Carlson, B. M.; Mitchell, B. A.; Mendoza-Halliday, D.; Westerberg, J. A.; Desimone, R.; Maier, A.; Kaas, J. H.; Bastos, A. M.
10.1101/2024.03.27.587084 — neuroscience — Posted on 2024-03-30
193 The Neural Basis of Attentional Blink as a Selective Control Mechanism in Conscious Perception
Xin, Q.; Forman, S.; Christison-Lagay, K.; Micek, C.; Kronemer, S.; Aksen, M.; Grobois, L.; Contreras Ramirez, V.; Khalaf, A.; Jin, D.; Aerts, S.; Chun, M.; Crowley, M.; Blumenfeld, H.
10.1101/2024.03.30.587354 — neuroscience — Posted on 2024-03-30
196 Transcriptomic analysis of the juvenile to adult transition in the mouse corpus callosum
Hoshino, T.; Takase, H.; Hamanaka, G.; Kimura, S.; Fukuda, N.; Mandeville, E. T.; Lok, J.; Lo, E. H.; Arai, K.
10.1101/2024.03.28.587148 — neuroscience — Posted on 2024-03-30
197 Lineage-tracing reveals an expanded population of NPY neurons in the inferior colliculus
Silveira, M. A.; Herrera, Y. N.; Beebe, N. L.; Schofield, B. R.; Roberts, M. T.
10.1101/2024.03.27.587042 — neuroscience — Posted on 2024-03-30
201 Wounding perception by jasmonate-mediated JAZ condensation in plants
Yan, Z.-W.; Liu, J.; Chen, H.-C.; Wang, M.-Y.; Cai, W.-J.; Li, J.-X.; Wang, J.-W.; Mao, Y.-B.
10.1101/2024.03.28.587122 — plant biology — Posted on 2024-03-30
203 Activation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP
Akerman, E. C.; Read, M. J.; Bose, S. J.; Koschinski, A.; Capel, R. A.; Chao, Y.-C.; Folkmanaite, M.; Hester, S.; Fischer, R.; Ayagama, T.; Broadbent, S. D.; Ahamed, R.; Simon, J. N.; Terrar, D. A.; Zaccolo, M.; Burton, R.-A. B.
10.1101/2024.03.28.583721 — physiology — Posted on 2024-03-30
207 multimedia: Multimodal Mediation Analysis of Microbiome Data
Jiang, H.; Miao, X.; Thairu, M. W.; Beebe, M.; Grupe, D. W.; Davidson, R. J.; Handelsman, J.; Sankaran, K.
10.1101/2024.03.27.587024 — bioinformatics — Posted on 2024-03-30
211 Design and Assembly of a Cargo-agnostic Hollow Two-lidded DNA Box for Drug Delivery
Koep, A.; Masud, N.; Van't Hul, J.; Stanley, C.; Nilsen-Hamilton, M.; Sarkar, A.; Schneider, I. C.
10.1101/2024.03.27.586853 — bioengineering — Posted on 2024-03-30
212 inSequio: A Programmable 3D CAD Application for Designing DNA Nanostructures
LaRock, C.; Sorensen, P.; Blair, D.; Murphy, D.; O'Connor, J.; Armentrout, S.
10.1101/2024.03.27.586810 — bioengineering — Posted on 2024-03-30
213 Glycoengineered recombinant alpha1-antitrypsin results in comparable in vitro and in vivo activities to human plasma-derived protein
Rocamora, F.; Schoffelen, S.; Arnsdorf, J.; Toth, E. A.; Abdul, Y.; Cleveland, T. E.; Bjorn, S. P.; Wu, M. Y. M.; McElvaney, N. G.; Voldborg, B. G. R.; Fuerst, T. R.; Lewis, N. E.
10.1101/2024.03.27.587088 — bioengineering — Posted on 2024-03-30
216 CARPDM: cost-effective antibiotic resistome profiling of metagenomic samples using targeted enrichment
Hackenberger, D.; Imtiaz, H.; Raphenya, A. R.; Alcock, B. P.; Poinar, H. N.; Wright, G. D.; McArthur, A. G.
10.1101/2024.03.27.587061 — genomics — Posted on 2024-03-30
217 The haplotype-resolved Prymnesium parvum (type B) microalga genome reveals the genetic basis of its fish-killing toxins
Kuhl, H.; Strassert, J. F. H.; Certnerova, D.; Varga, E.; Kreuz, E.; Lamatsch, D. K.; Wuertz, S.; Köhler, J.; Monaghan, M. T.; Stöck, M.
10.1101/2024.03.27.587007 — genomics — Posted on 2024-03-30
220 GENETIC DIVERSITY AFFECTS ECOSYSTEM FUNCTIONS ACROSS TROPHIC LEVELS AS MUCH AS SPECIES DIVERSITY, BUT IN AN OPPOSITE DIRECTION
Fargeot, L.; Poesy, C.; Lefort, M.; Prunier, J. G.; Krick, M.; Verdonck, R.; Veyssiere, C.; Richard, M.; Legrand, D.; Loot, G.; Blanchet, S.
10.1101/2024.03.27.586944 — ecology — Posted on 2024-03-30
222 Effect of urbanization on the city pollution based on soil and tree leaves in Valencia, Spain
Edina, S.; Bin, I. H.; Sipos, B.; Abriha-Molnar, V. E.; Abriha, D.; Boluda, H. R.; Perez, L. R.
10.1101/2024.03.27.586674 — ecology — Posted on 2024-03-30
226 Violated predictions enhance the representational fidelity of visual features in perception
Rideaux, R.; Dang, P.; Jackel-David, L.; Buhmann, Z.; Rangelov, D.; Mattingley, J. B.
10.1101/2024.03.27.587109 — neuroscience — Posted on 2024-03-30
227 Lipid Specificity of the Fusion of Bacterial Extracellular Vesicles with the Host Membrane
Prince, A.; Tiwari, A.; Mandal, T.; Koiri, D.; Meher, G.; Sinha, D. K.; Saleem, M.
10.1101/827519 — biophysics — Posted on 2024-03-30
228 A high-throughput method for quantifying Drosophila fecundity
Gomez, A.; Gonzalez, S.; Oke, A.; Luo, J.; Duong, J. B.; Esquerra, R. M.; Zimmerman, T.; Capponi, S.; Fung, J. C.; Nystul, T. G.
10.1101/2024.03.27.587093 — genetics — Posted on 2024-03-30
229 Development of Pial Collaterals by Extension of Pre-existing Artery Tips
Kumar, S.; Shanavas, N.; Ghosh, S.; Sivaramakrishnan, V.; Dwari, M.; Das, S.
10.1101/2023.12.07.570539 — developmental biology — Posted on 2024-03-30
230 MX2 restricts HIV-1 and herpes simplex virus type 1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes
Moschonas, G. D.; Delhaye, L.; Cooreman, R.; Husers, F.; Bath, A.; De Sutter, D.; Parthoens, E.; Desmet, A.-S.; Maciejczuk, A.; Grzesik, H.; Lippens, S.; Debyser, Z.; Sodeik, B.; Eyckerman, S.; Saelens, X.
10.1101/2023.06.22.545931 — microbiology — Posted on 2024-03-30
237 Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants
Arassi, M. B.; Karcher, N.; Mastrorilli, E.; Gross, M.; Brauer-Nikonow, A.; Hackett, R.; Czock, D.; Toenshoff, B.; Zeller, G.; Zimmermann, M.
10.1101/2024.03.28.586928 — microbiology — Posted on 2024-03-30
238 Learning enhances behaviorally relevant representations in apical dendrites
Benezra, S. E.; Patel, K. B.; Perez Campos, C.; Hillman, E. M. C.; Bruno, R. M.
10.1101/2021.11.10.468144 — neuroscience — Posted on 2024-03-30
240 Neural Correlates of Different Randomization Tasks
Guseva, M.; Bogler, C.; Allefeld, C.; Ziya, E. B.; Haynes, J.-D.
10.1101/2024.03.27.586961 — neuroscience — Posted on 2024-03-30
241 Dynamic Gamma Modulation of Hippocampal Place Cells Predominates Development of Theta Sequences
Wang, N.; Wang, Y.; Guo, M.; Wang, L.; Wang, X.; Zhu, N.; Yang, J.; Wang, L.; Zheng, C.; Ming, D.
10.1101/2024.03.27.586908 — neuroscience — Posted on 2024-03-30
243 A Set of FMRI Quality Control Tools in AFNI: Systematic, in-depth and interactive QC with afni_proc.py and more
Taylor, P. A.; Glen, D.; Chen, G.; Cox, R. W.; Hanayik, T.; Rorden, C.; Nielson, D. M.; Rajendra, J. K.; Reynolds, R. C.
10.1101/2024.03.27.586976 — neuroscience — Posted on 2024-03-30
244 Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.
Hoffner, G.; Castro, P.; Uhrig, L.; Signorelli, C. M.; Dupont, M.; Tasserie, J.; Destexhe, A.; Cofre, R.; Sitt, J.; Jarraya, B.
10.1101/2024.03.27.586806 — neuroscience — Posted on 2024-03-30
247 A new cellular platform for studying autophagy
Goldin-Azulay, K.; Fraiberg, M.; Trofimyuk, O.; Reuven, N.; Levin, Y.; Kopitman, E.; Elazar, Z.
10.1101/2024.03.28.587157 — cell biology — Posted on 2024-03-30
248 DIETARY REGULATION OF SILENT SYNAPSES IN THE DORSOLATERAL STRIATUM
Meyers, A. M.; Gnazzo, F.; Barrera, E. D.; Nabatian, T.; Chan, L.; Beeler, J.
10.1101/2024.03.24.586457 — neuroscience — Posted on 2024-03-30
250 LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
Busley, A. V.; Gutierrez-Gutierrez, O.; Hammer, E.; Koitka, F.; Mirzaiebadizi, A.; Steinegger, M.; Pape, C.; Boehmer, L.; Schroeder, H.; Kleinsorge, M.; Engler, M.; Cirstea, I. C.; Gremer, L.; Willbold, D.; Altmueller, J.; Marbach, F.; Hasenfuss, G.; Zimmermann, W.-H.; Ahmadian, M. R.; Wollnik, B.; Cyganek, L.
10.1101/2023.01.10.523203 — cell biology — Posted on 2024-03-29
251 Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons
Subedi, A.; Tiwari, A.; Etemad, A. F.; Huang, Y.; Chatterjee, B.; McLeod, S. L.; Lu, Y.; Gonzalez, D.; Ghosh, K.; Singh, S. K.; Ruiz Echartea, M. E.; Grimm, S. L.; Coarfa, C.; Pan, H.-L.; Majumder, S.
10.1101/2024.02.17.579842 — neuroscience — Posted on 2024-03-29
256 Shear Stress Initiates Endothelial to Mesenchymal Transition in Endocardial Endothelial Cells
Brown, K. N.; Phan, H. K. T.; Mustafa, T.; Jui, E.; Ahmad, F. N.; Birla, R. K.; Connell, J. P.; Sucosky, P.; Keswani, S. G.; Grande-Allen, K. J.
10.1101/2022.12.05.519049 — bioengineering — Posted on 2024-03-29
258 Evolution of Opsin Genes in Caddisflies (Insecta: Trichoptera)
Powell, A.; Heckenhauer, J.; Pauls, S. U.; Rios-Touma, B.; Kuranishi, R. B.; Holzenthal, R. W.; Razuri-Gonzales, E.; Bybee, S.; Frandsen, P. B.
10.1101/2023.12.15.571940 — genomics — Posted on 2024-03-29
259 Aging-associated long non-coding RNA boosts longevity and reduces the ribosome content of non-dividing fission yeast cells
Anver, S.; Sumit, A. F.; Sun, X.-M.; Hatimy, A.; Thalassinos, K.; Marguerat, S.; Alic, N.; Bahler, J.
10.1101/2024.03.25.586524 — genetics — Posted on 2024-03-29
262 Defining the function of disease variants with CRISPR editing and multimodal single cell sequencing
Baglaenko, Y.; Curtis, M.; Al Suqri, M.; Agnew, R.; Mire, H. M.; Mah-Som, A. Y.; Liu, D. R.; Newby, G. A.; Raychaudhuri, S.
10.1101/2024.03.28.587175 — genomics — Posted on 2024-03-29
263 Molecular insights into G protein specificity and biased agonism at the β2-adrenergic receptor
Casiraghi, M.; Wang, H.; Brennan, P.; Habrian, C.; Hubner, H.; Schmidt, M. F.; Maul, L.; Pani, B.; Bahriz, S. M.; Xu, B.; White, E.; Sunahara, R. K.; Xiang, Y. K.; Lefkowitz, R. J.; Isacoff, E. Y.; Nucci, N.; Gmeiner, P.; Lerch, M.; Kobilka, B. K.
10.1101/2024.03.28.587240 — molecular biology — Posted on 2024-03-29
266 Remodeling Ca2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer.
Chatterjee, O.; Jana, J.; Panda, S.; Dutta, A.; Sharma, A.; Saurav, S.; Motiani, R. K.; Weisz, K.; Chatterjee, S.
10.1101/2024.03.28.587164 — biochemistry — Posted on 2024-03-29
267 Uncovering nick DNA binding by LIG1 at the single-molecule level
Chatterjee, S.; Chaubet, L.; Berg, A. v. d.; Mukhortava, A.; Caglayan, M.
10.1101/2024.03.28.587287 — biochemistry — Posted on 2024-03-29
270 Wrapping of single-stranded DNA by Replication Protein A and modulation through phosphorylation
Chadda, R.; Kaushik, V.; Ahmad, I. M.; Deveryshetty, J.; Holehouse, A. S.; Sigurdsson, S. T. d.; Bothner, B.; Dastvan, R.; Origanti, S. S.; Antony, E.
10.1101/2024.03.28.587234 — biochemistry — Posted on 2024-03-29
271 An artificial intelligence accelerated virtual screening platform for drug discovery
Zhou, G.; Rusnac, D.-V.; Park, H.; Canzani, D.; Nguyen, H. M.; Stewart, L.; Bush, M. F.; Nguyen, P. T.; Wulff, H.; Yarov-Yarovoy, V.; Zheng, N.; DiMaio, F.
10.1101/2024.03.28.587262 — biochemistry — Posted on 2024-03-29
275 Striated fibre assemblins localise in the feeding groove of the 'typical excavate' Paratrimastix pyriformis
Heiss, A. A.; Fang, Y.-K.; Pena-Diaz, P.; Zitek, J.; Novak, J.; Smida, A.; Zelena, M.; Svagr, E.; Hampl, V.
10.1101/2024.03.29.587336 — microbiology — Posted on 2024-03-29
277 Effect of shipping on the microbiome of donor mice used to reconstitute germ-free recipients
McAdams, Z. L.; Yates, J.; Turner, G.; Dorfmeyer, R.; Wight-Carter, M.; Amos-Landgraf, J. M.; Franklin, C. L.; Ericsson, A. C.
10.1101/2024.03.29.587359 — microbiology — Posted on 2024-03-29
279 Three Modes of Viral Adaption by the Heart
Griffiths, C. D.; Shah, M.; Shao, W.; Borgman, C. A.; Janes, K. A.
10.1101/2024.03.28.587274 — systems biology — Posted on 2024-03-29
280 The PIN2 ortholog in barley modifies root gravitropism and architecture without impacting the shoot
Aldiss, Z.; Robinson, H.; Lam, Y.; Dixon, R.; Crisp, P. A.; Godwin, I. D.; Borrell, A.; Hickey, L.; Massel, K.
10.1101/2024.03.28.587117 — plant biology — Posted on 2024-03-29
283 Open Educational Resources for distributed hands-on teaching in molecular biology
Cerda Rojas, A.; Aravena, A.; Arce, A.; Zapata, V.; Araya, W.; Gallardo, D.; Aviles, J.; Quero, F.; Nunez, I.; Matute, T.; Navarro, F.; Ferrando, V.; Blanco, M.; Velozo, S.; Aguilera, S.; Chateau, F.; Molloy, J. C.; Aidelberg, G.; Lindner, A. B.; Castro, F.; Cremades, P.; Ramirez-Sarmiento, C. A.; Federici, F.
10.1101/2024.03.28.587173 — molecular biology — Posted on 2024-03-29
284 The ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection
Gatica, D.; Alsaadi, R. M.; El Hamra, R.; Mueller, R.; Miyazaki, M.; Sad, S.; Russell, R.
10.1101/2024.03.28.587227 — molecular biology — Posted on 2024-03-29
287 Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin
Wang, Z.; Zhu, J.; Wang, Y.; Chen, S.; Xu, S.; Li, Y.; Hu, T.; Li, Y.; Wang, X.; Ji, R.; Li, S. C.; Yang, Y.; Jia, H.; Chen, X.; Fan, X.; Ge, L.; Zhang, J.
10.1101/2024.03.28.587170 — molecular biology — Posted on 2024-03-29
290 Broad-Spectrum Coronavirus Inhibitors Discovered by Modeling Viral Fusion Dynamics
Reilly, C. B.; Moore, J.; Lightbown, S.; Paul, A. J.; Bernier, S. G.; Carlson, K. E.; Ingber, D. D.
10.1101/2024.03.28.587229 — microbiology — Posted on 2024-03-29
291 Plasmodium falciparum disruption of pericyte angiopoietin-1 secretion contributes to barrier breakdown in a 3D brain microvessel model
Long, R. K. M.; Korbmacher, F.; Ronchi, P.; Fleckenstein, H.; Mirza, W.; Mallorqui, M.; Aguilar, R.; Moncunill, G.; Schwab, Y.; Bernabeu, M.
10.1101/2024.03.29.587334 — microbiology — Posted on 2024-03-29
293 Enhanced mucosal B- and T-cell responses against SARS-CoV-2 after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant.
Laghlali, G.; Wiest, M. J.; Karada, D.; Warang, P.; O'Konek, J. J.; Chang, L. A.; Park, S.; Farazuddin, M.; Landers, J. J.; Janczak, K. W.; Garcia-Sastre, A.; Baker, J. R.; Wong, P. T.; Schotsaert, M.
10.1101/2024.03.28.587260 — immunology — Posted on 2024-03-29
294 SKP2-mediated FBXO2 proteasomal degradation drives hepatocellular carcinoma progression via stabilizing Hsp47
Xue, C.; Yang, F.; Bao, G.; Yan, J.; Fu, R.; Zhang, M.; Ding, J.; Feng, J.; Han, J.; Qin, X.; Su, H.; Sun, B.
10.1101/2024.03.28.586926 — cancer biology — Posted on 2024-03-29
295 Origins of noise in both improving and degrading decision making
Shen, B.; Wilson, J. M.; Nguyen, D.; Glimcher, P. W.; Louie, K.
10.1101/2024.03.26.586597 — neuroscience — Posted on 2024-03-29
296 Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target using a New Chemical Probe
Lynch, K. R.; Kharel, Y.; Huang, T.; Dunnavant, K.; Foster, D.; Santos, W.; Xu, W.; Gaultier, A.; Merchak, A.; Leitinger, N.; Pavelec, C.; Abbott, S. B.; Souza, G. M.; Nimchuk, K. T.; Shin, J.-B.
10.1101/2024.03.26.586765 — pharmacology and toxicology — Posted on 2024-03-29
297 Particulate matter constituents trigger the formation of extracellular amyloid beta and Tau-containing plaques and neurite shortening in vitro
Sebastijanovic, A.; Camassa, L. M. A.; Malmborg, V.; Kralj, S.; Pagels, J.; Vogel, U.; Zienolddiny-Narui, S.; Urbancic, I.; Koklic, T.; Strancar, J.
10.1101/2024.03.27.586796 — pharmacology and toxicology — Posted on 2024-03-29
298 The Hyaluronan Synthase isoforms direct distinct patterns of fibroblast activation linked to fibrosis progression versus resolution following renal ischaemia
Grigorieva, I.; Midgley, A.; Brown, C.; Chavez, G.; Williams, A.; Manetta-Jones, D.; Bowen, T.; Chan, D.; Plaas, A.; Chavez, R.; Steadman, R.; Khalid, U.; Meran, S.
10.1101/2024.03.27.586996 — pathology — Posted on 2024-03-29
299 Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons
Fugon, O. J. G.; Sharifi, O.; Heath, N. G.; Soto, D. C.; Gomez, J. A.; Yasui, D. H.; Mendiola, A. J. P.; O'Geen, H.; Beitnere, U.; Tomkova, M.; Haghani, V.; Dillon, G.; Segal, D. J.; LaSalle, J.
10.1101/2024.03.26.586689 — genetics — Posted on 2024-03-29
300 Exhaustion profile on classical monocytes after LPS stimulation in patients with Crohn's disease.
Oliveira, L. P.; Xavier, R. G.; Nora, C. C.; Mangueira, C. L.; Rosseto, E. A.; Aloia, T.; Gil, J. Z.; Scavanini Neto, A.; Lopes, F. B.; Carvalho, K. I.
10.1101/2024.03.28.587307 — immunology — Posted on 2024-03-29
301 Role of the NOS-cGMP pathways in time-dependent sensitization of behavioral responses in zebrafish
de Souza, E. B.; Heymbeeck, J. A. A.; Feitosa, L. M.; Xavier, A. G. O.; Almeida, C. E. d. S.; da Cruz, E. V.; Campos, K. d. S.; dos Santos Rodrigues, L. d. S.; de Freitas, L. M.; da Silva Brito, M. G.; do Carmo Silva, R. X.; Torres, S. L. d. P.; Ikeda, S. R.; Silva, S. d. N. d. S.; Rocha, S. P.; Brito Dias, T. P.; do Nascimento, W. L.; Moraes, E. R. d. S.; Herculano, A. M.; Maximino, C.; Pereira, A.; Lima-Maximino, M.
10.1101/2024.03.27.586937 — neuroscience — Posted on 2024-03-29
303 Navigating Human Astrocyte Differentiation: Direct and Rapid one-step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network development
Schuurmans, I. M. E.; Mordelt, A.; Linda, K.; Puvogel, S.; Duineveld, D.; Hommersom, M. P.; Rahm, L.; Dyke, E.; Scholten, G.-J.; Knorz, C.; Oudakker, A.; van Bokhoven, H.; de Witte, L. D.; van Karnebeek, C. D. M.; Garanto, A.; Kasri, N. N.
10.1101/2024.03.27.586938 — neuroscience — Posted on 2024-03-29
306 ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration
Pourshafie, N.; Xu, H.; Yang, K.; Donahue, G.; Lei, X.; Zhang, S.; Shcherbakova, O.; Hogan, C.; Gilbert, M.; Hoxha, K.; Chanoub, L.; Lee, V.; Adams, P.; Dani, J. A.; Bonini, N. M.; Berger, S. L.
10.1101/2024.03.27.586865 — neuroscience — Posted on 2024-03-29
307 GABAAR-PPT1 palmitoylation homeostasis controls synaptic transmission and circuitry oscillation in CLN1 disease
Ge, L.; Tong, J.; Gao, J.; Qi, Y.; Gao, Z.; Liu, Y.; Wang, Q.; Yuan, T.; Ren, M.; Yang, G.; Li, Z.; Li, J.; Sun, H.; Zhao, X.; Li, J.; Leung, Y.-Y.; Mu, Y.; Xu, J.; Lu, C.; Peng, S.
10.1101/2024.03.26.585929 — neuroscience — Posted on 2024-03-29
312 A Comprehensive Model of Blood Flow Restriction in the Post-surgical Rat
Fosam, A.; Nakandakari, S. C. B. R.; Ohashi, Y.; Bai, H.; O'Connell, J.; Raines, A.; Chavez Miranda, I.; Dardik, A.; Allen, C.; Perry, R. J.
10.1101/2024.03.27.586962 — animal behavior and cognition — Posted on 2024-03-29
313 GenoTools: An Open-Source Python Package for Efficient Genotype Data Quality Control and Analysis
Vitale, D.; Koretsky, M.; Kuznetsov, N.; Hong, S.; Martin, J.; James, M.; Makarious, M. B.; Leonard, H.; Iwaki, H.; Faghri, F.; Blauwendraat, C.; Singleton, A. B.; Song, Y.; Levine, K.; Sreelatha, A. A. K.; Fang, Z.-H.; Nalls, M. A.
10.1101/2024.03.26.586362 — genomics — Posted on 2024-03-29
314 Mixed Wolbachia infections resolve rapidly during in vitro evolution
Mirchandani, C.; Wang, P.; Jacobs, J.; Genetti, M.; Pepper-Tunick, E.; Sullivan, W. T.; Corbett-Detig, R.; Russell, S. L.
10.1101/2024.03.27.586911 — evolutionary biology — Posted on 2024-03-29
315 Intramuscular prime/intranasal boost vaccination to induce sterilizing immunity against influenza A virus infection
Avanthay, R.; Garcia-Nicolas, O.; Ruggli, N.; Grau-Roma, L.; Parraga-Ros, E.; Summerfield, A.; Zimmer, G.
10.1101/2024.03.27.586965 — immunology — Posted on 2024-03-29
319 Plasma Proteomics of Genetic Brain Arteriosclerosis and Dementia Syndrome Identifies Signatures of Fibrosis, Angiogenesis, and Metabolic Alterations
Keller, J. N.; Radabaugh, H.; Karvelas, N.; Fitzsimons, S.; Treiman, S.; Palafox, M. F.; McDonnell, L.; Quiroz, Y. T.; Lopera, F. J.; Banerjee, D.; Wang, M. M.; Arboleda-Velasquez, J. F.; Meschia, J. F.; Ferguson, A. R.; Elahi, F. M.
10.1101/2024.03.28.587249 — neuroscience — Posted on 2024-03-29
320 An EEG Signature of MCH Neuron Activities Predicts Cocaine Seeking
Wang, Y.; Li, D.; Widjaja, J.; Guo, R.; Cai, L.; Yan, R.; Ozsoy, S.; Allocca, G.; Fang, J.; Dong, Y.; Tseng, G. C.; Huang, C.; Huang, Y. H.
10.1101/2024.03.27.586887 — neuroscience — Posted on 2024-03-29
324 Unraveling Axonal Transcriptional Landscapes: Insights from iPSC-Derived Cortical Neurons and Implications for Motor Neuron Degeneration
Xu, J.; Hoerner, M.; Nagel, M.; Korneck, M.; Noss, M.; Hauser, S.; Schoels, L.; Admard, J.; Casadei, N.; Schuele, R.
10.1101/2024.03.26.586780 — neuroscience — Posted on 2024-03-29
326 Construction of Animal Models Based on Exploring Pathological Features and Mechanisms of Different Locations in the Progression of DVT-APTE-CTEPD/CTEPH
Huang, L. Q.; Feng, W. W.; Yun, C. X.; Xiang, L. J.; Nan, S.; Xia, W. Q.; Yue, L. X.; He, C. M.; Min, C.; Jing, W. Y.; Wen, W. D.; Li, L. H.; Ran, Y. P.; Xia, Z. Y.; Zhu, Z.; Guo, Z. Z.; Sheng, D. C.
10.1101/2024.03.28.587300 — zoology — Posted on 2024-03-29
329 Evidence that the monoamine oxidase B (MAO-B) plays a central role in the inotropic dysfunction induced by genetic deletion of the Mas-related-G protein-coupled receptor D (MrgD) in mice
Rodrigues-Ribeiro, L.; Rezende-Ribeiro, J.; Scalzo, S.; Dias-Pinto, M. L.; Sanches, B. d. L.; Eliezeck, M.; de Jesus, I. C.; Evaristo, J. A. M.; Sampaio, K. H.; Peruchetti, D. B.; Cruz, J. S.; Nogueira, F. C. S.; Campagnole-Santos, M. J.; Guatimosim, S.; Santos, R. A. S.; Verano-Braga, T.
10.1101/2024.03.27.586916 — physiology — Posted on 2024-03-29
331 Airway succinate chemosensing induces CFTR-dependent anion secretion and mucus clearance which is impaired in cystic fibrosis.
Apablaza, T.; Barros-Poblete, M.; Delpiano, L.; Villanueva, S.; Guequen, A.; Tapia-Balladares, B.; Haq, I. J.; Tribinos, F.; Hernandez-Rivas, S.; Verdon, B.; Biggart, M. G.; Sanchez, Y.; Ward, C.; Baxter, B. D.; Restrepo, D.; Cornejo, I.; Tarran, R.; Catalan, M. A.; Gray, M.; Flores, C. A.
10.1101/2024.03.26.586799 — physiology — Posted on 2024-03-29
339 Hemoglobin gene repertoire in teleost and cichlid fishes shaped by gene duplications and genome rearrangements
Omelchenko, D.; Bitja-Nyom, A. R.; Matschiner, M.; Malinsky, M.; Indermaur, A.; Salzburger, W.; Bartos, O.; Musilova, Z.
10.1101/2024.03.26.586788 — evolutionary biology — Posted on 2024-03-29
342 Plasma cell heterogeneity is driven by type of immune challenge
Khamyath, M.; Lereclus, E.; Gourhand, V.; Debureaux, P.-E.; Moulin, C.; Gary, H.; Bachelerie, F.; Balabanian, K.; Espeli, M.; Bonaud, A.
10.1101/2024.03.26.586773 — immunology — Posted on 2024-03-29
343 ZFAND6 is a subunit of a TRAF2-cIAP E3 ubiquitin ligase complex essential for mitophagy
Shaikh, K.; Bowman, M.; McCormick, S. M.; Gao, L.; Zhang, J.; Tawil, J.; Kapoor, A.; Arav-Boger, R.; Choi, Y. B.; Pekosz, A.; Klein, S. L.; Lanza, M.; Fanburg-Smith, J. C.; Garcia-Sastre, A.; Norbury, C. C.; Chroneos, Z.; Harhaj, E. W.
10.1101/2024.03.27.586763 — immunology — Posted on 2024-03-29
344 Cytosolic sodium accumulation is a cellular danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation
Mangan, M. S. J.; Akbal, A.; Rivara, S.; Horvath, G. L.; Walch, P.; Hegermann, J.; Kaiser, R.; Duthie, F.; Selkrig, J.; Gerhard, R.; Wachten, D.; Latz, E.
10.1101/2024.03.26.586774 — immunology — Posted on 2024-03-29
345 Heterogeneity of morphometric similarity networks in health and schizophrenia
Janssen, J.; Gallego, A. G.; Diaz-Caneja, C. M.; Lois, N. G.; Janssen, N.; Gonzalez-Penas, J.; Macias, P.; Buimer, E.; van Haren, N.; Arango, C.; Kahn, R.; Hulshoff Pol, H.; Schnack, H.
10.1101/2024.03.26.586768 — neuroscience — Posted on 2024-03-29
348 A novel GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 13 is involved in the Phosphate starvation-induced lipid remodeling in rice
Dang, D. T. T.; Nguyen, L. T.; Tran, T. A.; Tran, T. T. T.; Tran, A. T.; Vo, K. T. X.; Jeon, J.-S.; Vu, T. V.; Kim, J.-Y.; Nguyen, N. P.; Chu, H. H.; Do, P. T.; To, H. T. M.
10.1101/2024.03.27.586571 — plant biology — Posted on 2024-03-29
350 Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers
Tang, J.; Weiser, N. E.; Wang, G.; Chowdhry, S.; Curtis, E. J.; Zhao, Y.; Wong, I. T.-L.; Marinov, G. K.; Li, R.; Hanoian, P.; Tse, E.; Hansen, R.; Plum, J.; Steffy, A.; Milutinovic, S.; Meyer, S. T.; Altemose, N.; Curtis, C.; Greenleaf, W. J.; Bafna, V.; Benkovic, S. J.; Pinkerton, A. B.; Kasibhatla, S.; Hassig, C. A.; Mischel, P. S.; Chang, H. Y.
10.1101/2024.03.29.586681 — cancer biology — Posted on 2024-03-29
351 Real-time transcriptomic profiling in distinct experimental conditions
Butto, T.; Pastore, S.; Mueller, M.; Iyer, K. V.; Muendnich, S.; Wierczeiko, A.; Friedland, K.; Helm, M.; Winz, M.-L.; Gerber, S.
10.1101/2024.03.26.586831 — bioinformatics — Posted on 2024-03-29
352 Cellects, a software to quantify cell expansion and motion
Boussard, A.; Arrufat, P.; Dussutour, A.; Perez-Escudero, A.
10.1101/2024.03.26.586795 — bioinformatics — Posted on 2024-03-29
353 AdjuSST: An Adjustable Surface Stiffness Treadmill
Price, M. A.; Locurto, D.; Abdikadirova, B.; Huber, M. E.; Hoogkamer, W.
10.1101/2024.03.25.586685 — bioengineering — Posted on 2024-03-29
354 Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia
Swanson, M. A.; Jiang, H.; Busquet, N.; Carlsen, J.; Brindley, C.; Benke, T. A.; Van Hove, R. A.; Friederich, M. W.; MacLean, K. N.; Mesches, M. A.; Van Hove, J. L.
10.1101/2024.03.26.586818 — animal behavior and cognition — Posted on 2024-03-29
355 Completion of the DrugMatrix Toxicogenomics Database using ToxCompl
Cong, G.; Patton, R. M.; Chao, F.; Svoboda, D. L.; Casey, W. M.; Schmitt, C. P.; Murphy, C.; Erickson, J. N.; Combs, P. A.; Auerbach, S. S.
10.1101/2024.03.26.586669 — genomics — Posted on 2024-03-29
358 Two highly selected mutations in the tandemly duplicated CYP6P4a and CYP6P4b drive pyrethroid resistance in Anopheles funestus
Tatchou-Nebangwa, N. M. T.; Mugenzi, L. M. J.; Muhammad, A.; Nebangwa, D. N.; Kouamo, M. F. M.; Tagne, C. S. D.; Tekoh, T. A.; Tchouakui, M.; Ghogomu, S. M.; Ibrahim, S. S.; Wondji, C. S.
10.1101/2024.03.26.586794 — genetics — Posted on 2024-03-29
359 Human ancestry inference at scale, from genomic data
Warren, R. L.; Coombe, L.; Wong, J.; Kazemi, P.; Birol, I.
10.1101/2024.03.26.586646 — genetics — Posted on 2024-03-29
360 Collective anti-predator escape manoeuvres through optimal attack and avoidance strategies
Bartashevich, P.; Herbert-Read, J. E.; Hansen, M. J.; Dhellemmes, F.; Domenici, P.; Krause, J.; Romanczuk, P.
10.1101/2024.03.26.586812 — ecology — Posted on 2024-03-29
362 MftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
Graca, A. P.; Nikitushkin, V.; Ellerhorst, M.; Vilhena, C.; Klassert, T.; Starick, A.; Siemers, M.; Al-Jammal, W. K.; Vilotijevic, I.; Slevogt, H.; Papenfort, K.; Lackner, G.
10.1101/2024.03.26.586840 — microbiology — Posted on 2024-03-29
363 De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assemblies
Beaulaurier, J.; Ly, L.; Duty, J. A.; Tyer, C.; Stevens, C.; Hung, C.-t.; Sookdeo, A.; Drong, A. W.; Kowdle, S.; Turner, D. J.; Juul, S.; Hickey, S.; Lee, B.
10.1101/2024.03.26.586834 — immunology — Posted on 2024-03-29
364 Butyrate and propionate are microbial danger signals that activate the NLRP3-inflammasome in human macrophages in the presence of TLR stimulation
Wang, W.; Dernst, A.; Martin, B.; Lorenzi, L.; Phulphagar, K.; Wagener, A.; Budden, C.; Stair, N.; Wagner, T.; Faerber, H.; Jaensch, A.; Stahl, R.; Duthie, F.; Schmidt, S. V.; Coll, R. C.; Meissner, F.; Cuartero, S.; Mangan, M. S. J.; Latz, E.
10.1101/2024.03.26.586782 — immunology — Posted on 2024-03-29
365 Holding glycolysis in check though Alox15 activity is required for macrophage M2 commitment and function in tissue repair and anti-helminth immunity.
Doolan, R.; Moyat, m.; Coakley, G.; Wickramasinghe Mudiyansel, L.; Daunt, C.; Volpe, B.; Henkel, F.; Trefzer, V.; Ubags, N.; Butler, A.; Chatzis, R.; Marsland, B.; Smith, A. A. T.; Deveson, D. L.; McGowan, E. N. S.; Binger, K. J.; Esser-von Bieren, J.; Bouchery, T.; Harris, N.
10.1101/2024.03.26.586755 — immunology — Posted on 2024-03-29
366 EEG biomarkers of GABA α5 positive allosteric modulators in rodents
Mazza, F.; Guet-McCreight, A.; Prevot, T. D.; Valiante, T. A.; Sibille, E.; Hay, E.
10.1101/2024.03.26.586837 — neuroscience — Posted on 2024-03-29
369 Sustained bias of spatial attention in a 3T MRI scanner
Smaczny, S.; Behle, L.; Kuppe, S.; Karnath, H.-O.; Lindner, A.
10.1101/2024.03.26.586826 — neuroscience — Posted on 2024-03-29
371 Model-based frequency-and-phase correction of 1H MRS data with 2D linear-combination modeling.
Simicic, D.; Zöllner, H. J.; Davies-Jenkins, C. W.; Hupfeld, K. E.; Edden, R. A. E.; Oeltzschner, G.
10.1101/2024.03.26.586804 — neuroscience — Posted on 2024-03-29
373 A Multiparametric Analysis Reveals Differential Behavior of Spheroid Cultures on Distinct Ultra-Low Attachment Plates Types
Vitacolonna, M.; Bruch, R.; Agaci, A.; Nuernberg, E.; Cesetti, T.; Keller, F.; Padovani, F.; Sauer, S.; Schmoller, K. M.; Reischl, M.; Hafner, M.; Rudolf, R.
10.1101/2024.03.26.586778 — cancer biology — Posted on 2024-03-29
375 Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
Xiang, G.; He, X.; Giardine, B. M.; Isaac, K. J.; Taylor, D. J.; McCoy, R. C.; Jansen, C.; Keller, C. A.; Wixom, A. Q.; Cockburn, A.; Miller, A.; Qi, Q.; He, Y.; Li, Y.; Lichtenberg, J.; Heuston, E. F.; Anderson, S. M.; Luan, J.; Vermunt, M. W.; Yue, F.; Sauria, M. E. G.; Schatz, M. C.; Taylor, J.; Gottgens, B.; Hughes, J. R.; Higgs, D. R.; Weiss, M. J.; Cheng, Y.; Blobel, G. A.; Bodine, D. M.; Zhang, Y.; Li, Q.; Mahony, S.; Hardison, R. C.
10.1101/2023.04.02.535219 — genomics — Posted on 2024-03-29
376 Sex chromosome turnover in African annual killifishes of the genus Nothobranchius
Hospodarska, M.; Mora, P.; Volenikova, A. C.; Al-Rikabi, A.; Simanovsky, S. A.; Pavlica, T.; Altmanova, M.; Janeckova, K.; Stundlova, J.; Tolar, N.; Jankasek, M.; Hirman, M.; Liehr, T.; Reichard, M.; Krysanov, E. Y.; Rab, P.; Englert, C.; Nguyen, P.; Sember, A.
10.1101/2024.03.25.586567 — evolutionary biology — Posted on 2024-03-29
378 Assessment of the efficacy of field and laboratory methods for the detection of Tropilaelaps spp.
Gill, M. C.; Chuttong, B.; Davies, P.; Etheridge, D.; Panyaraksa, L.; Tomkies, V.; Tonge, G.; Budge, G. E.
10.1101/2024.03.26.586849 — ecology — Posted on 2024-03-29
379 Nutrient addition in grasslands worldwide reveals proportional plant diversity decline across spatial scales but little change in beta diversity
Chen, Q.; Blowes, S.; Ladouceur, E.; Harpole, S.; Seabloom, E. W.; Tognetti, P. M.; MacDougall, A.; Daleo, P.; Hautier, Y.; Stevens, C.; Morgan, J.; Veen, C.; Risch, A. C.; Roscher, C.; Bakker, J. D.; Adler, P.; Borer, E.; Niu, Y.; Peri, P. L.; Martina, J.; Eisenhauer, N.; Virtanen, R.; Power, S.; Catford, J.; Tedder, M.; Bagchi, S.; Wheeler, G.; Haider, S.; Maria, C.; Bugalho, M.; Knops, J.; Dickman, C.; Hagenah, N.; Jentsch, A.; Wardle, G.; Estrada, C.; Donohue, I.; Gruner, D.; Olde Venterink, H.; Lannes, L.; Hersch-Green, E.; Chase, J.
10.1101/2024.03.27.586835 — ecology — Posted on 2024-03-29
380 The homeobox transcription factor Cux1 coordinates postnatal epithelial developmental timing but is dispensable for lung organogenesis and regeneration
Zhao, B.; Socha, J.; Fernandes, S.; Warheit-Niemi, H.; Ruff, B.; Hershey, G. K. K.; VanDussen, K. L.; Swarr, D. T.; Zacharias, W. J.
10.1101/2024.03.26.586673 — developmental biology — Posted on 2024-03-29
381 Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope
Le Bozec, B.; Guitton-Sert, L.; Collins, S.; Finoux, A.-L.; Payrault, C.; Frison, J.; Carette, R.; Rocher, V.; Guillou, E.; Arnould, C.; Guenole, A.; Aguirrebengoa, M.; Lazar, I.; Marnef, A.; Frit, P.; Calsou, P.; Mangeat, T.; Puget, N.; Legube, G.
10.1101/2023.05.11.540338 — molecular biology — Posted on 2024-03-29
384 M2 macrophages dampen in utero sterile inflammation to prevent preterm birth and improve neonatal outcomes
Garcia-Flores, V.; Liu, Z.; Romero, R.; Xu, Y.; Miller, D.; Galaz, J.; Winters, A. D.; Farias-Jofre, M.; Panzer, J. J.; Theis, K. R.; Gomez-Lopez, N.
10.1101/2023.07.19.549717 — immunology — Posted on 2024-03-29
387 Chilean brush tailed mouse (Octodon degus): a diurnal precocial rodent as a new model to study visual receptive field properties of superior colliculus neurons
Marquez, N. I.; Fernandez-Aburto, P. F.; Deichler, A.; Perales, I.; Letelier, J.-C.; Marin, G. J.; Mpodozis, J.; Pallas, S. L.
10.1101/2024.03.25.586655 — neuroscience — Posted on 2024-03-29
388 Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model
Yao, M.; Wei, Z.; Nielsen, J. S.; Kakazu, A.; Ouyang, Y.; Li, R.; Chu, T.; Scafidi, S.; Lu, H.; Aggarwal, M.; Duan, W.
10.1101/2024.03.25.586662 — neuroscience — Posted on 2024-03-29
389 Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice
McFadden, S. A.; Peck, M. R.; Sime, L. N.; Cox, M. F.; Ikiz, E. D.; Findley, C. A.; Quinn, K.; Fang, Y.; Bartke, A.; Hascup, E. R.; Hascup, K. N.
10.1101/2024.03.26.586836 — neuroscience — Posted on 2024-03-29
390 Neurovascular unit adjustments following chronic distress explain motivational deficits in mice
Cabeza, L.; Mor, D.; Ramadan, B.; Benhora-Chabeaux, G.; Houdayer, C.; Haffen, E.; Peterschmitt, Y.; Etievant, A.; Bourasset, F.
10.1101/2024.03.25.586557 — neuroscience — Posted on 2024-03-29
391 Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess neuronal epitranscriptome plasticity
Fanari, O.; Tavakoli, S.; Akeson, S.; Makhamreh, A.; Nian, K.; McCormick, C. A.; Qiu, Y.; Bloch, D.; Jain, M.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2024.03.26.586895 — systems biology — Posted on 2024-03-29
392 Cortisol levels, heart rate, and autonomic responses in horses during repeated road transport with different truck conditions trucks in a tropical environment
Lertratanachai, S.; Poochipakorn, C.; Sanigavatee, K.; Huangsaksri, O.; Wonghanchao, T.; Charoenchanikran, P.; Lawsirirat, C.; Chanda, M.
10.1101/2024.03.26.586854 — physiology — Posted on 2024-03-29
396 Uncovering microstructural architecture from histology
Georgiadis, M.; auf der Heiden, F.; Abbasi, H.; Ettema, L.; Nirschl, J.; Moein Taghavi, H.; Wakatsuki, M.; Liu, A.; Ho, W. H. D.; Carlson, M.; Doukas, M.; Koppes, S. A.; Keereweer, S.; Sobel, R. A.; Setsompop, K.; Liao, C.; Amunts, K.; Axer, M.; Zeineh, M. M.; Menzel, M.
10.1101/2024.03.26.586745 — pathology — Posted on 2024-03-29
397 Loss of Lkb1 cooperates with BrafV600E and UV radiation increasing melanoma multiplicity and neural-like dedifferentiation
McGrail, K. A.; Gonzlez-Sanchez, E.; Granado-Martinez, P.; Orsenigo, R.; Ding, Y.; Ferrer, B.; Hernandez-Losa, J.; Ortega, I.; Martin-Caballero, J.; Munoz-Couselo, E.; Garcia-Patos, V.; Recio, J. A.
10.1101/2024.03.29.587140 — cancer biology — Posted on 2024-03-29
398 Comparison of the tolerability of terbium-161 and lutetium-177 in combination with somatostatin analogues in the preclinical setting
Busslinger, S. D.; Mapanao, A. K.; Kegler, K.; Bernhardt, P.; Fluehmann, F.; Fricke, J.; Zeevaart, J. R.; Koester, U.; van der Meulen, N. P.; Schibli, R.; Mueller, C.
10.1101/2024.03.29.587329 — cancer biology — Posted on 2024-03-29
400 NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis
Parolia, A.; Eyunni, S.; Verma, B. K.; Young, E.; Liu, L.; George, J.; Aras, S.; Das, C. K.; Mannan, R.; ur Rasool, R.; Luo, J.; Carson, S. E.; Mitchell-Velasquez, E.; Liu, Y.; Xiao, L.; Gajjala, P. R.; Jaber, M.; Wang, X.; He, T.; Qiao, Y.; Pang, M.; Zhang, Y.; Alhusayan, M.; Cao, X.; Tavana, O.; Hou, C.; Wang, Z.; Ding, K.; Chinnaiyan, A. M.; Asangani, I. A.
10.1101/2024.02.22.581560 — cancer biology — Posted on 2024-03-29
401 VISION -- an open-source software for automated multi-dimensional image analysis of cellular biophysics
Weber, F.; Iskrak, S.; Ragaller, F.; Schlegel, J.; Plochberger, B.; Sezgin, E.; Andronico, L.
10.1101/2024.03.29.587344 — biophysics — Posted on 2024-03-29
404 Development of AI-assisted microscopy frameworks through realistic simulation in pySTED
Bilodeau, A.; Michaud-Gagnon, A.; Chabbert, J.; Turcotte, B.; Heine, J.; Durand, A.; Lavoie-Cardinal, F.
10.1101/2024.03.25.586697 — bioinformatics — Posted on 2024-03-29
405 Systematic Evaluation of Cell Type Deconvolution Methods for Plasma Cell-free DNA
Sun, T.; Yuan, J.; Zhu, Y.; Yang, S.; Zhou, J.; Ge, X.; Qu, S.; Li, W.; Li, J. J.; Li, Y.
10.1101/2024.03.25.586507 — bioinformatics — Posted on 2024-03-29
410 Non-invasive optoacoustic imaging visualizes exercise-induced dermal revascularization in obese mice
Huang, S.; He, H.; Tom, R. Z.; Glasl, S.; Anzenhofer, P.; Stiel, A. C.; Hofmann, S.; Ntziachristos, V.
10.1101/2024.03.26.586767 — bioengineering — Posted on 2024-03-29
411 Rationalizing diverse binding mechanisms to the same protein fold: in-sights for ligand recognition and biosensor design
Leonard, A. C.; Friedman, A. J.; Chayer, R.; Petersen, B. M.; Kaar, J.; Shirts, M. R.; Whitehead, T. A.
10.1101/2024.03.25.586677 — bioengineering — Posted on 2024-03-29
414 Diverse prey capture strategies in teleost larvae
Mearns, D. S.; Hunt, S. A.; Schneider, M. W.; Parker, A. V.; Stemmer, M.; Baier, H.
10.1101/2023.10.03.560453 — animal behavior and cognition — Posted on 2024-03-29
417 Transposable element expression with variation in sex chromosome number supports a toxic Y effect on human longevity
Teoli, J.; Merenciano, M.; Fablet, M.; Necsulea, A.; Siqueira-de-Oliveira, D.; Brandulas-Cammarata, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Bardel, C.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — genomics — Posted on 2024-03-29
425 Leiomodin 1 promotes myogenic differentiation by modulating Sirtuin 1
Spath, E.; Schuler, S. C.; Heinze, I.; Dau, T. T. D.; Minetti, A.; Hofmann, M.; von Maltzahn, J.; Ori, A.
10.1101/2024.03.29.587321 — cell biology — Posted on 2024-03-29
428 Root-associated Streptomyces produce galbonolides to modulate plant immunity and promote rhizosphere colonisation
Nicolle, C.; Gayrard, D.; Noel, A.; Hortala, M.; Amiel, A.; Grat, S.; Le Ru, A.; Marti, G.; Pernodet, J.-L.; Lautru, S.; Dumas, B.; Rey, T.
10.1101/2024.01.20.576418 — microbiology — Posted on 2024-03-29
430 CD4+ Trm sustain the chronic phase of auto-immune neuroinflammatory disease
Pignata, A.; Frieser, D.; Hsiao, C.-C.; Engelenburg, H. J.; Alis, M.; Gonzalez-Fierro, C.; Cazaentre, V.; Miranda-Capet, R.; Dufourd, E.; Vermeulen, T.; Aida, A.; Vangisbergen, K.; Blanchard, N.; Hamann, J.; Smolders, J.; Liblau, R.; Masson, F.
10.1101/2024.03.26.586880 — immunology — Posted on 2024-03-29
431 Human long noncoding RNA, VILMIR, is induced by major respiratory viral infections and modulates the host interferon response
John, K.; Huntress, I.; Smith, E.; Chou, H.; Tollison, T. S.; Covarrubias, S.; Crisci, E.; Carpenter, S.; Peng, X.
10.1101/2024.03.25.586578 — immunology — Posted on 2024-03-29
432 KIR3DL1 and Tox identify clonally expanded encephalitogenic neuron-specific CD8+ T cells in autoimmune encephalitis
Perriot, S.; Jones, S.; Genolet, R.; Mathias, A.; Lindsay, H.; Bobisse, S.; Di Liberto, G.; Canales, M.; Queiroz, L.; Sauvage, C.; Wagner, I.; Oberholster, L.; Gimenez, M.; Begarie, D.; Theaudin, M.; Pot, C.; Merkler, D.; Gottardo, R.; Harari, A.; Du Pasquier, R.
10.1101/2024.03.25.586688 — immunology — Posted on 2024-03-29
433 Anabolic lipid metabolism regulates adipose type 2 innate lymphoid cell differentiation to maintain metabolic health
Theodorou, M. R.; Yu, J.; Nikolka, F.; Zurkovic, J.; Wientjens, C.; Weiss, P.; Rombo, R.; Karagiannis, F.; Thiele, C.; Hasenauer, J.; Hiller, K.; Wilhelm, C.
10.1101/2024.03.26.586766 — immunology — Posted on 2024-03-29
434 Complement activation by IgG subclasses is governed by their ability to oligomerize upon antigen binding
Frischauf, N.; Strasser, J.; Borg, E. G. F.; Labrijn, A. F.; Beurskens, F. J.; Preiner, J.
10.1101/2024.03.26.586731 — immunology — Posted on 2024-03-29
435 Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1alpha axis plays a key role in host resistance to Plasmodium infection
Matteucci, K. C.; Assis, P. A.; Hirako, I. C.; Leite, N. P. S.; Pioto, F.; OJELABI, O.; E. TOLLER-KAWAHISA, J.; Costa, D. L.; S. Silva, J.; Alves-Filho, J. C.; Gazzinelli, R.
10.1101/2024.03.26.586751 — immunology — Posted on 2024-03-29
436 Thalamic blood flow and EEG frequency band power during hyperventilation in idiopathic generalized epilepsy
Debatisse, J.; Yaakub, S. N.; De Vita, E.; Charles-Edwards, G.; Jeljeli, S.; Stirling, J.; Flaus, A.; Dunn, J.; Koutroumanidis, M.; Hammers, A.; McGinnity, C. J.
10.1101/2024.03.26.586742 — neuroscience — Posted on 2024-03-29
438 Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function
Ono, K.; Jarysta, A.; Hughes, N.; Jukic, A.; Chang, V. H. H.; Deans, M. R.; Eatock, R. A.; Cullen, K. E.; Kindt, K. S.; Tarchini, B.
10.1101/2024.03.26.586740 — neuroscience — Posted on 2024-03-29
439 Effects of early life adversity and adolescent basolateral amygdala inhibition on corticolimbic connectivity and anxiety behaviors
Cody, C. R.; Artur de la Villarmois, E.; Auger, M.; Miguelez Fernandez, A.; Lardizaball, J.; McKnight, C.; Tseng, K.; Brenhouse, H. C.
10.1101/2024.03.26.586708 — neuroscience — Posted on 2024-03-29
440 Exploring dynamic brain oscillations in motor imagery and low-frequency sound
Dupont, W.; Poulin-Charronnat, B.; Madden Lombardi, C.; Jacquet, T.; Pfister, P.; Dos Anjos, T.; Lebon, F.
10.1101/2024.03.26.586734 — neuroscience — Posted on 2024-03-29
441 Associations between parenting and cognitive and language abilities at age 2 depend on prenatal exposure to disadvantage
Leverett, S. D.; Brady, R. G.; Tooley, U. A.; Lean, R. E.; Tillman, R.; Wilson, J.; Ruscitti, M.; Triplett, R. L.; alexopoulos, D.; Gerstein, E. D.; Smyser, T. A.; Warner, B.; Luby, J. D.; Smyser, C. D.; Rogers, C. E.; Barch, D. M.
10.1101/2024.03.25.586610 — neuroscience — Posted on 2024-03-29
446 Non-canonical adrenergic neuromodulation of motoneuron intrinsic excitability through beta-receptors in wild-type and ALS mice
Antonucci, S.; Caron, G.; Dikwella, N.; Krishnamurthy, S. S.; Zarrin, H.; Tahanis, A.; Olde Heuvel, F.; Danner, S. M.; Ludolph, A. C.; Grycz, K.; Baczyk, M.; Zytnicki, D.; Roselli, F.
10.1101/2024.03.25.586570 — neuroscience — Posted on 2024-03-29
448 Distinct Motor Map Characteristics for Biceps and Triceps Muscles in Persons with Chronic Tetraplegia: Implications for Arm Function
Liu, J.; Olaughlin, K.; Forrest, G. F.; Arora, T.; Nemunaitis, G.; Cunningham, D.; Kirshblum, S.; Pundik, S.; Baker, K.; Bryden, A.; Kilgore, K.; Bethoux, F.; Wang, X.; Henzel, M. K.; Brihmat, N.; Bayram, M. B.; Plow, E. B.
10.1101/2024.03.27.585546 — neuroscience — Posted on 2024-03-29
449 Functional-based parcellation of the mouse prefrontal cortex for network perturbation analysis
Savvateev, I.; Grimm, C.; Markicevic, M.; Grandjean, J.; Wenderoth, N.; Polania, R.; Zerbi, V.
10.1101/2024.03.25.586664 — neuroscience — Posted on 2024-03-29
451 A split-GAL4 driver line resource for Drosophila CNS cell types
Meissner, G. W.; Vannan, A.; Jeter, J.; Atkins, M.; Bowers, S.; Close, K.; DePasquale, G. M.; Dorman, Z.; Forster, K.; Beringer, J. A.; Gibney, T. V.; Gulati, A.; Hausenfluck, J. H.; He, Y.; Henderson, K.; Johnson, L.; Johnston, R. M.; Ihrke, G.; Iyer, N.; Lazarus, R.; Lee, K.; Li, H.-H.; Liaw, H.-P.; Melton, B.; Miller, S.; Motaher, R.; Novak, A.; Ogundeyi, O.; Petruncio, A.; Price, J.; Protopapas, S.; Tae, S.; Tata, A.; Taylor, J.; Vorimo, R.; Yarbrough, B.; Zeng, K. X.; Zugates, C. T.; Dionne, H.; Angstadt, C.; Ashley, K.; Cavallaro, A.; Dang, T.; Gonzalez, G. A.; Hibbard, K. L.; Huang, C.;
10.1101/2024.01.09.574419 — neuroscience — Posted on 2024-03-29
453 Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models
Pech, U.; Janssens, J.; Schoovaerts, N.; Kuenen, S.; Makhzami, S.; Hulselmans, G.; Poovathingal, S.; Bademosi, A. T.; Swerts, J.; Vilain, S. P.; Aerts, S.; Verstreken, P.
10.1101/2023.03.11.532176 — neuroscience — Posted on 2024-03-29
454 Acute and sub-chronic toxicity of 6PPD-quinone to early-life stage lake trout (Salvelinus namaycush)
Roberts, C.; Lin, J.; Kohlman, E.; Jain, N.; Amekor, M.; Alcaraz, A. J.; Hogan, N.; Hecker, M.; Brinkmann, M.
10.1101/2024.03.26.586843 — physiology — Posted on 2024-03-29
458 Reliable cross-ion mode chemical similarity prediction between MS2 spectra
de Jonge, N. F.; Joas, D.; Truong, L.-J.; van der Hooft, J. J. J.; Huber, F.
10.1101/2024.03.25.586580 — bioinformatics — Posted on 2024-03-29
460 hoodscanR: profiling single-cell neighborhoods in spatial transcriptomics data
Liu, N.; Martin, J.; Bhuva, D. D.; Chen, J.; Li, M.; Lee, S. C.; Kharbanda, M.; Cheng, J.; Mohamed, A.; Kulasinghe, A.; Chen, Y.; Tan, C. W.; Davis, M. J.
10.1101/2024.03.26.586902 — bioinformatics — Posted on 2024-03-29
461 Baselining the Buzz. Trastuzumab-HER2 Affinity, and Beyond!
Chinery, L.; Hummer, A. M.; Mehta, B. B.; Akbar, R.; Rawat, P.; Slabodkin, A.; Le Quy, K.; Lund-Johansen, F.; Greiff, V.; Jeliazkov, J. R.; Deane, C. M.
10.1101/2024.03.26.586756 — bioinformatics — Posted on 2024-03-29
463 py_ped_sim - A flexible forward genetic simulator for complex family pedigree analysis
Guardado, M. A.; Perez, C.; Campana, S.; Chavez-Rojas, B.; Magana, J.; Jackson, S.; Samperio, E.; Syas, K.; Hernandez, S.; Hernandez, R.; Zavala, E.; Rohlfs, R.
10.1101/2024.03.25.586501 — bioinformatics — Posted on 2024-03-29
465 Strain-resolved de-novo metagenomic assembly of viral genomes and microbial 16S rRNAs
Jochheim, A.; Jochheim, F. E.; Kolodyazhnaya, A.; Morice, E.; Steinegger, M.; Soeding, J.
10.1101/2024.03.29.587318 — bioinformatics — Posted on 2024-03-29
466 Matrimeres are systemic nanoscale mediators of tissue integrity and function
Debnath, K.; Qayoom, I.; O'Donnell, S.; Ekiert, J.; Wang, C.; Sanborn, M. A.; Liu, C.; Rivera, A.; Cho, I. S.; Saichellappa, S.; Toth, P. T.; Mehta, D.; Rehman, J.; Du, X.; Gao, Y.; Shin, J.-W.
10.1101/2024.03.25.586585 — bioengineering — Posted on 2024-03-29
468 Unravelling the glycome in human intervertebral disc degeneration: Aberrant glycosylation modulates inflammation and metabolism.
Joyce, K.; Scheper, A. F.; Phyo, A. M.; O'Flaherty, R.; Drake, R.; Devitt, A.; Marchetti-Deschmann, M.; Saldova, R.; Pandit, A.
10.1101/2024.03.26.585840 — bioengineering — Posted on 2024-03-29
470 Comparative framework and adaptation of ACME HS approach to single cell isolation from fresh-frozen endocrine tissues
Utkina, M.; Shcherbakova, A.; Deviatiiarov, R.; Ryabova, A.; Marina Loguinova, M.; Trofimov, V.; Kuznetsova, A.; Petropavlovskiy, M.; Salimkhanov, R.; Maksimov, D.; Albert, E.; Golubeva, A.; Asaad, W.; Urusova, L.; Bondarenko, E.; Lapshina, A.; Shutova, A.; Beltsevich, D.; Gusev, O.; Dzeranova, L.; Melnichenko, G.; Minniakhmetov, I.; Dedov, I.; Mokrysheva, N.; Popov, S.
10.1101/2024.03.26.586727 — genomics — Posted on 2024-03-29
477 Delayed localization of A-type lamins to the rupture sites in Hutchinson-Gilford progeria syndrome
Kono, Y.; Pack, C.-G.; Ichikawa, T.; Komatsubara, A.; Adam, S. A.; Miyazawa, K.; Rolas, L.; Nourshargh, S.; Medalia, O.; Goldman, R. D.; Fukuma, T.; Kimura, H.; Shimi, T.
10.1101/2023.09.02.555826 — cell biology — Posted on 2024-03-29
478 Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes
Mora-Bitria, L.; Debebe, B. J.; Miners, K.; Ladell, K.; Kaur, C.; Traherne, J. A.; Jiang, W.; Hadcocks, L.; McQuibban, N. A. R.; Trowsdale, J.; Wong, F. S.; Pontikos, N.; Niederalt, C.; Asquith, B.
10.1101/2024.03.27.586933 — immunology — Posted on 2024-03-29
479 Mitochondria-Associated Membranes Are Not Altered In Immune Cells In T2D
Hart, S. N.; Lenin, R.; Sturgill, J.; Kern, P. A.; Nikolajczyk, B. S.
10.1101/2024.03.25.586170 — immunology — Posted on 2024-03-29
480 Splicing-aware resolution of scRNA-Seq data
Lukyanov, D. K.; Egorov, E. S.; Kriukova, V. V.; Ladell, K.; Price, D.; Franke, A.; Chudakov, D. M.
10.1101/2024.03.25.586675 — immunology — Posted on 2024-03-29
482 Functional states of prelimbic and related circuits during the acquisition of a GO/noGO task in rats
Munoz-Redondo, C.; Parras, G. G.; Andreu-Sanchez, C.; Martin-Pascual, M. A.; DELGADO-GARCIA, J. M.; Gruart, A.
10.1101/2024.03.25.586558 — neuroscience — Posted on 2024-03-29
483 A role for δ subunit-containing GABA-A receptors on parvalbumin positive neurons in maintaining electrocortical signatures of sleep states
Lambert, P. M.; Salvatore, S. V.; Lu, X.; Shu, H.-J.; Benz, A.; Rensing, N.; Yuede, C.; Wong, M.; Zorumski, C. F.; Mennerick, S.
10.1101/2024.03.25.586604 — neuroscience — Posted on 2024-03-29
484 How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimers disease brain by a strain-relief mechanism
Hou, K.; Ge, P.; Sawaya, M. R.; Dolinsky, J. L.; Yang, Y.; Jiang, Y. X.; Lutter, L.; Boyer, D. R.; Cheng, X.; Pi, J.; Zhang, J.; Lu, J.; Yang, S.; Yu, Z.; Feigon, J.; Eisenberg, D. S.
10.1101/2024.03.25.586668 — neuroscience — Posted on 2024-03-29
485 Goal-directed vocal planning in a songbird
Zai, A. T.; Stepien, A. E.; Giret, N.; Hahnloser, R. H. R.
10.1101/2022.09.27.509747 — neuroscience — Posted on 2024-03-29
486 Modulation of Temporoammonic-CA1 Synapses by Neuropeptide Y is Through Y1 Receptors
Cortes, M. A.; Bartley, A. F.; Li, Q.; Davis, T. R.; Cunningham, S. E.; Perez, P. J.; Dobrunz, L. E.
10.1101/2024.03.26.586875 — neuroscience — Posted on 2024-03-29
490 Expert Navigators Deploy Rational Hierarchical Priorization Over Predictive Maps For Large-Scale Real-World Planning
Fernandez Velasco, P.; Griesbauer, E.-M.; Brunec, I.; Morley, J.; Manley, E.; McNamee, D.; Spiers, H.
10.1101/2024.03.25.586612 — neuroscience — Posted on 2024-03-29
493 Metatranscriptomics-based metabolic modeling of patient-specific urinary microbiome during infection
Josephs-Spaulding, J.; Rettig, H. C.; Zimmermann, J.; Chkonia, M.; Mischnik, A.; Franzenburg, S.; Graspeuntner, S.; Rupp, J.; Kaleta, C.
10.1101/2024.03.25.586446 — systems biology — Posted on 2024-03-29
494 Guava cv. Allahabad Safeda Chromosome scale assembly and comparative genomics decodes breeder choice marker trait association for pink pulp colour
Mittal, A.; Thakur, S.; Sharma, A.; Boora, R. S.; Arora, N. K.; Singh, D.; Gill, M. S.; Dhillon, G. S.; Chhuneja, P.; Yadav, I.; Jindal, M.; Mathew, O. K.; Lachagari, V. B. R.; Paterson, A. H.
10.1101/2024.03.29.587319 — plant biology — Posted on 2024-03-29
495 Seamless, rapid and accurate analyses of outbreak genomic data using Split K-mer Analysis (SKA)
Derelle, R.; von Wachsmann, J.; Maeklin, T.; Hellewell, J.; Russell, T.; Lalvani, A.; Chindelevitch, L.; Croucher, N. J.; Harris, S. R.; Lees, J. A.
10.1101/2024.03.25.586631 — bioinformatics — Posted on 2024-03-29
496 Proposing a Systematic Lineage Classification Below the Genotype Level for Dengue Serotypes 1 and 2
Pereira, J. S.; Ribeiro, G.; de Souza, V. C.; Brcko, I. C.; Ribeiro, I. S.; De Lima, I. T. T.; Slavov, S. N.; Vessoni, S. C. S.; Sabbaga, M. C.; Lima, A. R. J.
10.1101/2024.03.25.586629 — bioinformatics — Posted on 2024-03-29
497 Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays
Shrestha, S.; Acharya, P.; Kang, S.-Y.; Vanga, M. G.; Lekkala, V. K. R.; Liu, J.; Yang, Y.; Joshi, P.; Lee, M.-Y.
10.1101/2024.03.25.586638 — bioengineering — Posted on 2024-03-29
499 Spatial and temporal characteristics of laboratory-induced Anopheles coluzzii swarms: shape, structure and flight kinematics
Poda, B. S.; Cribellier, A.; Feugere, L.; Fatou, M.; Nignan, C.; Hien, D. F. d. S.; Müller, P.; Gnankine, O.; Dabire, R. K.; Diabate, A.; Muijres, F. T.; Roux, O.
10.1101/2024.03.25.586329 — animal behavior and cognition — Posted on 2024-03-29
500 Development of sound production in Danionella cerebrum
Groneberg, A. H.; Dressler, L. E.; Kadobianskyi, M.; Muller, J.; Judkewitz, B.
10.1101/2024.03.25.586601 — animal behavior and cognition — Posted on 2024-03-29
502 Transcriptomic, clonal, and functional analyses reveal Liver tissue-imprinted immuno-profile of circulating autoreactive CD4 T cells in autoimmune liver diseases
Cardon, A.; Guinebretiere, T.; Dong, C.; Gil, L.; Ado, S.; Gavlovsky, P.-j.; Braud, M.; Danger, R.; Schultheiss, C.; Domene, A.; Paul-Guilloteaux, P.; Chevalier, C.; Bernier, L.; Judor, J.-P.; Fourgeux, C.; Imbert, A.; Khaldi, M.; Bardou-Jacquet, E.; Elkrief, L.; Lannes, A.; Silvain, C.; Schnee, M.; Tanne, F.; Vavasseur, F.; Brusselle, L.; Brouard, S.; Kwok, W.; Mosnier, J.-F.; Lohse, A. W.; Poschmann, J.; Binder, M.; Gournay, J.; Conchon, S.; Milpied, P.; Renand, A.
10.1101/2024.03.26.586770 — immunology — Posted on 2024-03-29
504 IT IS NOT A SMALL WORLD FOR PSYCHIATRIC PATIENTS
Akin, A.; Yorgancigil, E.; Ozturk, O. C.; Sutcubasi, B.; Kirimli, C. E.; Kirimli, E. E.; Dumlu, S. N.; Yukselen, G.; Erdogan, S. B.
10.1101/2024.03.25.586529 — neuroscience — Posted on 2024-03-29
505 Aging-associated long non-coding RNA boosts longevity and reduces the ribosome content of non-dividing fission yeast cells
Anver, S.; Sumit, A. F.; Sun, X.-M.; Hatimy, A.; Thalassinos, K.; Marguerat, S.; Alic, N.; Bahler, J.
10.1101/2024.03.25.586524 — genetics — Posted on 2024-03-29
506 Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants
Arassi, M. B.; Karcher, N.; Mastrorilli, E.; Gross, M.; Brauer-Nikonow, A.; Hackett, R.; Czock, D.; Toenshoff, B.; Zeller, G.; Zimmermann, M.
10.1101/2024.03.28.586928 — microbiology — Posted on 2024-03-29
507 LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice
Cobo-vuilleumier, N.; Rodriguez-Fernandez, S.; Lopez-Noriega, L.; Lorenzo, P. I.; Franco, J. M.; Lachaud, c. C.; Martin-Vazquez, E.; Araujo Legido, R.; Dorronsoro, A.; Lopez-Fernandez-Sobrino, R.; Fernandez-santos, b.; Salas-Lloret, D.; van Overbeek, N.; Ramos-Rodriguez, M.; Mateo-Rodriguez, C.; Hidalgo, L.; Nano, R.; Arroba, A. I.; Campos Caro, A.; Vertegaal, A. C.; Martin Montalvo, A.; Martin, F.; Aguilar-Diosdado, M.; Piemonti, L.; Pasquali, L.; Gonzalez Prieto, R.; Garcia Sanchez, M. I.; Martinez-Brocca, M.; Vives-Pi, M.; Gauthier, B. R.
10.1101/2023.09.18.558230 — cell biology — Posted on 2024-03-29
508 Characterization of West Nile virus Koutango lineage from Phlebotomine Sandflies in Kenya 2021
Thiiru, J. W.; Langat, S.; Mulwa, F.; Cinkovich, S.; Koka, H.; Yalwala, S.; Khamadi, S.; Onguso, J.; Odemba, N.; Ngere, F.; Johnson, J.; Egbo, T.; Garges, E.; Ojwang, E.; Eyase, F.
10.1101/2024.03.27.587075 — microbiology — Posted on 2024-03-29
509 Endosomal sorting protein SNX4 limits synaptic vesicle docking and release
Poppinga, J.; Barret, N. J.; Cornelisse, L. N.; Verhage, M.; van Weering, J. R. T.
10.1101/2024.03.15.584406 — neuroscience — Posted on 2024-03-29
510 Ketogenic Diet Induces Anti-Tumorigenic Effects in Colorectal Cancer through Microbial Production of Stearate
Tsenkova, M.; Brauer, M.; Kasakin, M.; Busi, S. B.; Schmoetten, M.; Gaigneaux, A.; Pozdeev, V.; Meyers, M.; Koncina, E.; Herebian, D.; Rodriguez, F.; Cheung, D.; Schmitz, M.; de Nies, L.; Mayatepek, E.; Haan, S.; de Beaufort, C.; Graas, J.; Cramer, T.; Linster, C.; Wilmes, P.; Letellier, E.
10.1101/2023.12.07.570549 — cancer biology — Posted on 2024-03-29
511 Assessing horizontal gene transfer in the rhizosphere of Brachypodium distachyon using fabricated ecosystems (EcoFABs)
Priya, S.; Rossbach, S.; Eng, T.; Andeer, P.; Lin, H.-H.; Mortimer, J.; Northen, T.; Mukhopadhyay, A.
10.1101/2024.03.14.584828 — microbiology — Posted on 2024-03-29
512 Siderophore-receptor coevolution analysis reveals habitat- and pathogen-specific bacterial iron interaction networks
Gu, S.; Shao, Z.; Qu, Z.; Zhu, S.; Shao, Y.; Zhang, D.; Allen, R.; He, R.; Shao, J.; Xiong, G.; Jousset, A.; Friman, V.-P.; Wei, Z.; Kuemmerli, R.; Li, Z.
10.1101/2023.11.05.565711 — microbiology — Posted on 2024-03-29
513 Differential increase of hippocampal subfield volume after socio-affective mental training relates to reductions in diurnal cortisol
Valk, S. L.; Engert, V.; Puhlmann, L.; Linz, R.; Caldairou, B.; Bernasconi, A.; Bernasconi, N.; Bernhardt, B. C.; Singer, T.
10.1101/2023.03.03.531039 — neuroscience — Posted on 2024-03-29
517 Capture of Human Neuromesodermal and Posterior Neural Tube Axial Stem Cells
Kelle, D.; Ugur, E.; Rusha, E.; Shaposhnikov, D.; Livigni, A.; Horschitz, S.; Davoudi, M.; Blutke, A.; Bushe, J.; Sterr, M.; Arkhipova, K.; Tak, B.; de Vries, R.; Hochane, M.; Spruijt, B.; Haji Ali, A.; Lickert, H.; Feuchtinger, A.; Koch, P.; Mann, M.; Leonhardt, H.; Wilson, V.; Drukker, M.
10.1101/2024.03.26.586760 — developmental biology — Posted on 2024-03-29
518 The transcription factor Tcf21 is required for specifying Foxd1 cells to the juxtaglomerular cell lineage
Anjum, H.; Yacu, G. S.; Medrano, S.; Gomez, R. A.; Sequeira-Lopez, M. L. S.; Quaggin, S. E.; Finer, G.
10.1101/2024.03.25.586641 — developmental biology — Posted on 2024-03-29
520 The homeobox transcription factor Cux1 coordinates postnatal epithelial developmental timing but is dispensable for lung organogenesis and regeneration
Zhao, B.; Socha, J.; Fernandes, S.; Warheit-Niemi, H.; Ruff, B.; Hershey, G. K. K.; VanDussen, K. L.; Swarr, D. T.; Zacharias, W. J.
10.1101/2024.03.26.586673 — developmental biology — Posted on 2024-03-29
522 Distinct Gene Regulatory Dynamics Drive Skeletogenic Cell Fate Convergence During Vertebrate Embryogenesis
Wang, M.; Di Pietro-Torres, A.; Feregrino, C.; Luxey, M.; Moreau, C.; Fischer, S.; Fages, A.; Tschopp, P.
10.1101/2024.03.26.586769 — developmental biology — Posted on 2024-03-29
524 Endothelial calcium firing mediates extravasation of metastatic tumor cells.
Peralta, M.; Dupas, A.; Larnicol, A.; Lefebvre, O.; Goswami, R.; Girardo, S.; Osmani, N.; Goetz, J. G.
10.1101/2024.03.28.587188 — cell biology — Posted on 2024-03-29
525 A modular and flexible open source cell incubator system for mobile and stationary use
Duru, J.; Maurer, B.; Ruff, T.; Hengsteler, J.; Girardin, S.; Voros, J.; Ihle, S. J.
10.1101/2024.03.27.587077 — cell biology — Posted on 2024-03-29
527 A new cellular platform for studying autophagy
Goldin-Azulay, K.; Fraiberg, M.; Trofimyuk, O.; Reuven, N.; Levin, Y.; Kopitman, E.; Elazar, Z.
10.1101/2024.03.28.587157 — cell biology — Posted on 2024-03-29
531 Nuclear blebs are associated with destabilized chromatin packing domains
Pujadas Liwag, E. M.; Acosta, N.; Almassalha, L. M.; Su, Y.; Gong, R.; Kanemaki, M. T.; Stephens, A. D.; Backman, V.
10.1101/2024.03.28.587095 — bioengineering — Posted on 2024-03-29
532 Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation
Niedner-Boblenz, A.; Monecke, T.; Hennig, J.; Klostermann, M.; Hofweber, M.; Davydova, E.; Gerber, A. P.; Anosova, I.; Mayer, W.; Mueller, M.; Heym, R.; Janowski, R.; Paillart, J.-C.; Dormann, D.; Zarnack, K.; Sattler, M.; Niessing, D.
10.1101/2024.03.27.586925 — biochemistry — Posted on 2024-03-29
533 Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species
Maeda, K.; Sumita, T.; Nishi, O.; Sushida, H.; Higashi, Y.; Nakagawa, H.; Suzuki, T.; Iwao, E.; Fanani, M. Z.; Nishiya, Y.; Iida, Y.
10.1101/2024.03.22.586281 — microbiology — Posted on 2024-03-29
535 A practical guide to time-resolved fluorescence microscopy and spectroscopy
Clark, B. S.; Silvernail, I.; Gordon, K.; Castaneda, J. F.; Morgan, A. N.; Rolband, L. A.; LeBlanc, S. J.
10.1101/2024.01.25.577300 — biophysics — Posted on 2024-03-29
536 Analog epigenetic cell memory by graded DNA methylation
Palacios, S.; Bruno, S.; Weiss, R.; Salibi, E.; Kane, A.; Ilia, K.; Del Vecchio, D.
10.1101/2024.02.13.580200 — bioengineering — Posted on 2024-03-29
539 Spring haul-out behavior of seals in the Bering and Chukchi seas
London, J. M.; Conn, P. B.; Koslovsky, S. M.; Richmond, E. L.; Ver Hoef, J. M.; Cameron, M. F.; Crawford, J. A.; Von Duyke, A. L.; Quakenbush, L.; Boveng, P. L.
10.1101/2022.04.07.487572 — ecology — Posted on 2024-03-29
540 Bayesian Optimization of Neurostimulation (BOONStim)
Oliver, L. D.; Jeyachandra, J.; Dickie, E. W.; Hawco, C.; Mansour, S.; Hare, S. M.; Buchanan, R. W.; Malhotra, A. K.; Blumberger, D. M.; Deng, Z.-D.; Voineskos, A. N.
10.1101/2024.03.08.584169 — neuroscience — Posted on 2024-03-29
544 Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a male mouse model of head-and-neck cancer
Barr, J.; Walz, A.; Restaino, A. C.; Amit, M.; Barclay, S. M.; Vichaya, E. G.; Spanos, W. C.; Dantzer, R.; Talbot, S.; Vermeer, P. D.
10.1101/2023.10.18.562990 — cancer biology — Posted on 2024-03-28
545 Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates
Latham, A. P.; Zhu, L.; Sharon, D. A.; Ye, S.; Willard, A. P.; Zhang, X.; Zhang, B.
10.1101/2023.03.30.534967 — biophysics — Posted on 2024-03-29
546 Biolearn, an open-source library for biomarkers of aging
Ying, K.; Paulson, S.; Eames, A.; Li, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Gobel, D.; Snyder, M.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.
10.1101/2023.12.02.569722 — bioinformatics — Posted on 2024-03-28
547 Wearable Disposable Electrotherapy
FallahRad, M.; Chaudhry, Z.; Belali Koochesfahani, M.; Bhuiyan, R.; Zaman, M.; Liu, T.; Saha, K.; Diaz Uraga, M. R.; Thahsin, M.; Couzis, A.; Bikson, M.
10.1101/2023.11.28.569062 — bioengineering — Posted on 2024-03-29
548 Diverse Database and Machine Learning Model to narrow the generalization gap in RNA structure prediction
de Lajarte, A.; Martin Des Taillades, Y.; Kalicki, C.; Fuchs, F.; Aruda, J.; Salazar, D.; Allan, M.; LEsperance-Kerckhoff, C.; Kashi, A.; Jossinet, F.; Rouskn, S.
10.1101/2024.01.24.577093 — biochemistry — Posted on 2024-03-29
549 MolEvolvR: A web-app for characterizing proteins using molecular evolution and phylogeny
Krol, J. D.; Burke, J. T.; Chen, S. Z.; Sosinski, L. M.; Alquaddoomi, F. S.; Brenner, E. P.; Wolfe, E. P.; Rubinetti, V. P.; Amolitos, S.; Reason, K. M.; Johnston, J. B.; Ravi, J.
10.1101/2022.02.18.461833 — genomics — Posted on 2024-03-29
551 Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation
Klokman, G.; Xu, Y.; Bond, K.; Wu, X.; Schustak, J.; Mandelbaum, J.; Twarog, M.; Han, H.; Paulina, M.-K.; Coble, M.; Hayden, C.; Galarneau, J.-R.; Demirs, J.; Qiu, Y.; Esterberg, R.; Huang, Q.; Prasanna, G.; Saint-Geniez, M.; Aranda, J.; Bao, Y.
10.1101/2024.03.11.584455 — cell biology — Posted on 2024-03-28
553 Multiscale chromatin dynamics and high entropy in plant iPSC ancestors
Rutowicz, K.; Luethi, J.; de Groot, R.; Holtackers, R.; Yakimovich, Y.; Pazmino, D. M.; Gandrillon, O.; Pelkmans, L.; Baroux, C.
10.1101/2023.09.28.559735 — molecular biology — Posted on 2024-03-28
554 Prediction of antibiotic resistance at the patient level using deep learning
Inda-Diaz, J. S.; Johnning, A.; Hessel, M.; Sjoberg, A.; Lokrantz, A.; Helldal, L.; Jirstrand, M.; Svensson, L.; Kristiansson, E.
10.1101/2023.05.09.539832 — microbiology — Posted on 2024-03-28
561 Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants
Arassi, M. B.; Karcher, N.; Mastrorilli, E.; Gross, M.; Brauer-Nikonow, A.; Hackett, R.; Czock, D.; Toenshoff, B.; Zeller, G.; Zimmermann, M.
10.1101/2024.03.28.586928 — microbiology — Posted on 2024-03-28
562 Characterization of sediment and granite hosted deep underground research laboratories reveals diverse microbiome functions, limited temporal variation and substantial genomic conservation
Amamo, Y.; Sachdeva, R.; Gittins, D.; Anantharaman, K.; Lei, S.; Valentin Alvarado, L. E.; Diamond, S.; Beppu, H.; Iwatsuki, T.; Mochizuki, A.; Miyakawa, K.; Ishii, E.; Murakami, H.; Jaffe, A. L.; Castelle, C.; Lavy, A.; Suzuki, Y.; Banfield, J. F.
10.1101/2024.03.28.587102 — microbiology — Posted on 2024-03-28
565 Genetic interaction library screening with a next-generation dual guide CRISPR system
Burgold, T.; Karakoc, E.; Goncalves, E.; Dwane, L.; Barrio-Hernandez, I.; Silva, R. O.; Souster, E.; Sharma, M.; Beck, A.; Koh, G.; Zalmas, L.-P.; Garnett, M.; Bassett, A. R.
10.1101/2024.03.28.587052 — molecular biology — Posted on 2024-03-28
567 Caught in a trap: DNA contamination in tsetse xenomonitoring can lead to over-estimates of Trypanosoma brucei infection
Saldanha, I.; Lea, R.; Manangwa, O.; Garrod, G.; Haines, L. R.; Acosta-Serrano, A.; Auty, H.; Betson, M.; Lord, J. S.; Morrison, L. J.; Mramba, F.; Torr, S. J.; Cunningham, L. J.
10.1101/2024.03.25.586549 — molecular biology — Posted on 2024-03-28
569 Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis
Rodriguez, L. R.; Alysandratos, K.-D.; Katzen, J.; Murthy, A.; Barboza, W. R.; Tomer, Y.; Acin-Perez, R.; Petcherski, A.; Minakin, K.; Carson, P.; Iyer, S.; Chavez, K.; Cooper, C. H.; Babu, A.; Weiner, A. I.; Vaughan, A. E.; Arany, Z.; Shirihai, O. S.; Kotton, D. N.; Beers, M. F.
10.1101/2024.03.26.586649 — molecular biology — Posted on 2024-03-28
571 Building a Collaborative DNA Barcode Library for the Diptera of Churchill, Canada: A Resource for Northern Research
Majoros, S. E.; Wang, J.; Levesque-Beaudin, V.; Borkent, C. J.; Brodo, F.; Brooks, S. E.; Boucher, S.; Cumming, J. M.; Currie, D. C.; Ekrem, T.; Elliott, T. A.; Hebert, P. D. N.; Savage, J.; Schaefer, P.; Sinclair, B. J.; Skevington, J. H.; Solecki, A. M.; Stur, E.; Wheeler, T. A.; Woodcock, T. S.; Young, A. D.; Young, C.; Adamowicz, S. J.
10.1101/2024.03.27.586819 — molecular biology — Posted on 2024-03-28
572 Plant Cleavage Factor I complex is essential for precise cleavage and polyadenylation site determination
Szewc, L.; Zhang, X.; Bajczyk, M.; Bielewicz, D.; Zimna, M.; Yura, K.; Mariko Kato, M.; Nomoto, M.; Garcia-Leon, M.; Rubio, V.; Tada, Y.; Furumoto, T.; Aoyama, T.; Szweykowska-Kulinska, Z.; Staiger, D.; Jarmolowski, A.; Tsuge, T.
10.1101/2024.03.28.587165 — molecular biology — Posted on 2024-03-28
574 The Role of Morphological Adaptability in Vibrio cholerae's Motility and Pathogenicity
Xu, J.; Abe, K.; Kodama, T.; Sultana, M.; Chac, D.; Markiewicz, S. M.; Kuba, E.; Tsunoda, S.; Alam, M.; Weil, A. A.; Nakamura, S.; Yamashiro, T.
10.1101/2024.03.27.586043 — microbiology — Posted on 2024-03-28
575 Characterization of West Nile virus Koutango lineage from Phlebotomine Sandflies in Kenya 2021
Thiiru, J. W.; Langat, S.; Mulwa, F.; Cinkovich, S.; Koka, H.; Yalwala, S.; Khamadi, S.; Onguso, J.; Odemba, N.; Ngere, F.; Johnson, J.; Egbo, T.; Garges, E.; Ojwang, E.; Eyase, F.
10.1101/2024.03.27.587075 — microbiology — Posted on 2024-03-28
576 IFNgamma-dependent remodelling of the myeloid landscape underlies control of IFNgamma-insensitive tumours
Lau, V. W. C.; Mead, G.; Mazet, J. M.; Krishnan, A.; Roberts, E. W.; Prota, G.; Gileadi, U.; Cerundolo, V.; Gerard, A.
10.1101/2024.03.25.586537 — immunology — Posted on 2024-03-28
577 Inflammation induced Th17 cells synergize with the inflammation-trained microbiota to mediate host-resiliency against intestinal injury
Golob, J. L.; Hou, G.; Swanson, B.; Bishu, S.; Grasberger, H.; El-Zaatari, M.; Lee, A.; Kao, J. Y.; Kamada, N.; Bishu, S.
10.1101/2024.03.25.586435 — immunology — Posted on 2024-03-28
583 Synthetic mycolates derivatives as molecular tools to decipher protein mycoloylation, a unique post-translational modification in bacteria.
Lesur, E.; Zhang, Y.; Dautin, N.; Dietrich, C.; Li de la Sierra-Gallay, I.; Augusto, L.; Rollando, P.; Lazar, N.; Urban, D.; Doisneau, G.; Constantinesco-Becker, F.; Van Tilbeurgh, H.; Guianvarc'h, D.; Bourdreux, Y.; Bayan, N.
10.1101/2024.03.28.587066 — microbiology — Posted on 2024-03-28
586 Development of differential sublaminar feedforward inhibitory circuits in CA1 hippocampus requires Satb2
Hanson, M. A.; Bibi, N.; Safa, A.; Nagarajan, D.; Marshall, A. H.; Johantges, A. C.; Wester, J. C.
10.1101/2024.01.23.576902 — neuroscience — Posted on 2024-03-28
587 Mechanical cues of extracellular matrix determines tumor innervation
Jiang, S.-H.; Zhang, S.; Cai, Z.; Yu, M.-H.; Li, H.; Jiang, L.; Cai, S.; Zhu, Y.; Wang, H.; Huo, R.-X.; Xia, X.; Yao, H.-F.; Zhu, L.; Zhang, X.-L.; Hu, L.-P.; Li, Q.; Li, J.; Huo, Y.-M.; Hua, R.; Xue, J.; Jiang, C.; Sun, Y.-W.; Zhang, J.-F.; Zhang, Z.-Z.; Liu, D.-J.; Xiao, G. G.-S.; Zhang, Z.-G.
10.1101/2024.03.25.586535 — neuroscience — Posted on 2024-03-28
588 Multiplexed 3D Analysis of Immune States and Niches in Human Tissue
Yapp, C.; Nirmal, A. J.; Zhou, F. Y.; Maliga, Z.; Tefft, J.; Montero Llopis, P.; Murphy, G. F.; Lian, C.; Danuser, G.; Santagata, S.; Sorger, P. K.
10.1101/2023.11.10.566670 — cancer biology — Posted on 2024-03-28
589 Label-guided seed-chain-extend alignment on annotated De Bruijn graphs
Mustafa, H.; Karasikov, M.; Mansouri Ghiasi, N.; Rätsch, G.; Kahles, A.
10.1101/2022.11.04.514718 — bioinformatics — Posted on 2024-03-28
590 Generative interpolation and restoration of images using deep learning for improved 3D tissue mapping
Joshi, S.; Forjaz, A.; Sang Han, K.; Shen, Y.; Queiroga, V.; Xenes, D.; Matelsky, J.; Wester, B.; Munoz-Barrutia, A.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.
10.1101/2024.03.07.583909 — bioinformatics — Posted on 2024-03-28
593 The Sociodemographic and Lifestyle Correlates of Epigenetic Aging in a Nationally Representative U.S. Study of Younger Adults
Harris, K. M.; Levitt, B. E.; Gaydosh, L.; Martin, C.; Meyer, J. M.; Mishra, A. A.; Kelly, A. L.; Aiello, A. E.
10.1101/2024.03.21.585983 — genomics — Posted on 2024-03-28
594 Sequence-based genome-wide association studies reveal the polygenic architecture of Varroa destructor resistance in Western honey bees Apis mellifera
Eynard, S. E.; Mondet, F.; Basso, B.; Bouchez, O. E.; Le Conte, Y.; Dainat, B.; Decourtye, A.; Genestout, L.; Guichard, M.; Guillaume, F.; Labarthe, E.; Locke, B.; Mahla, R.; de Miranda, J. R.; Neuditschko, M.; Phocas, F.; Tabet, K.; Vignal, A.; Servin, B.
10.1101/2024.02.16.580755 — genetics — Posted on 2024-03-28
596 Bacterial pathogens dynamic during multi-species infections
Barny, M.-A.; Thieffry, S.; Gomes de Faria, C.; Thebault, E.; Pedron, J.
10.1101/2023.12.06.570389 — microbiology — Posted on 2024-03-28
597 Molecular epidemiology of Cercospora leaf spot on resistant and susceptible sugar beet hybrids
Chen, C.; Keunecke, H.; Neu, E.; Kopisch-Obuch, F. J.; McDonald, B. A.; Stapley, J.
10.1101/2023.10.30.564591 — pathology — Posted on 2024-03-28
598 Three-dimensional assessments are necessary to determine the true, spatially-resolved composition of tissues
Forjaz, A.; Vaz, E.; Romero, V. M.; Joshi, S.; Braxton, A. M.; Jiang, A. C.; Fujikura, K.; Cornish, T.; Hong, S.-M.; Hruban, R. H.; Wu, P.-H.; Wood, L. D.; Kiemen, A. L.; Wirtz, D.
10.1101/2023.12.04.569986 — cancer biology — Posted on 2024-03-28
600 Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells
Valverde-Mendez, D.; Sunol, A. M.; Bratton, B. P.; Delarue, M.; Hofmann, J. L.; Sheehan, J. P.; Gitai, Z.; Holt, L. J.; Shaevitz, J. W.; Zia, R. N.
10.1101/2024.03.27.587083 — biophysics — Posted on 2024-03-28
603 Functional phases define the response of the soil microbiome to environmental change
Lee, K. K.; Liu, S.; Crocker, K.; Huggins, D. R.; Tikhonov, M.; Mani, M.; Kuehn, S.
10.1101/2024.03.15.584851 — ecology — Posted on 2024-03-28
606 Lossless Single-Molecule Counting To Absolute QuantifyProteoforms
Gross, T.; Hundertmark, T.; Csiszar, V.; Sulyok, A. A.; Gross, N.; Breiden, M.; Kitschen, N.; von Groll, U.; Niemoller, C.; Sanchez-Martin, P.; Hein, A.; Gopffert, J.; Szoradi, T.; Luebbert, P.; Koltay, P.; Porschewski, P.; von Stetten, F.; Zengerle, R.; Jeney, C.
10.1101/2024.03.19.585761 — molecular biology — Posted on 2024-03-28
610 Convergent evolution of desiccation tolerance in grasses
Marks, R. A.; Van Der Pas, L.; Schuster, J.; Gilman, I. S.; VanBuren, R.
10.1101/2023.11.29.569285 — plant biology — Posted on 2024-03-28
611 Novel synthetic ecteinascidins exhibit potent anti-melanoma activity by suppressing super-enhancer-driven oncogenic transcription
Cigrang, M.; Obid, j.; Davidson, i.; Nogaret, M.; ye, t.; davidson, g.; Catez, P.; Berico, P.; capelli, c.; Marechal, C.; Zachayus, A.; Elly, C.; Li, T.-K.; Compe, E.; Aviles, P.; egly, j.-m.; Cuevas, C.; Coin, F.
10.1101/2024.03.26.586754 — cancer biology — Posted on 2024-03-28
613 A zebrafish system for identifying genetic dependencies in melanocytes and melanoma
Perlee, S.; Ma, Y.; Hunter, M. V.; Swanson, J. B.; Ming, Z.; Xia, J.; Lionnet, T.; McGrail, M.; White, R.
10.1101/2024.03.22.586101 — genetics — Posted on 2024-03-28
614 Latitudinal scaling of aggregation with abundance and its consequences for coexistence in species rich forests
Wiegand, T.; Wang, X.; Fischer, S.; Kraft, N. J. B.; Bourg, N. A.; Brockelman, W. Y.; Cao, M.; Chanthorn, W.; Chu, C.; Davies, S.; Ediriweera, S.; Gunatilleke, C. V. S.; Gunatilleke, I. A. U. N.; Hao, Z.; Howe, R.; Jiang, M.; Jin, G.; Kress, W. J.; Li, B.; Lian, J.; Lin, L.; Liu, F.; Ma, K.; McShea, W.; Mi, X.; Myers, J. A.; Nathalang, A.; Orwig, D. A.; Shen, G.; Su, S.-H.; Sun, I.-F.; Wang, X.; Wolf, A.; Yan, E.; Ye, W.; Zhu, Y.; Huth, A.
10.1101/2023.05.18.541254 — ecology — Posted on 2024-03-28
616 Altered X-chromosome inactivation predisposes to autoimmunity
Huret, C.; Ferraye, L.; David, A.; Mohamed, M.; Valentin, N.; Charlotte, F.; Savignac, M.; Goodhardt, M.; Guery, J.-C.; Rougeulle, C.; Morey, C.
10.1101/2023.04.20.537662 — immunology — Posted on 2024-03-28
618 Variations of autonomic arousal mediate the reportability of mind-blanking occurrences
Boulakis, P. A.; Simos, N. J.; Zoi, S.; Mortaheb, S.; Schmidt, C.; Raimondo, F.; Demertzi, A.
10.1101/2024.03.26.586648 — neuroscience — Posted on 2024-03-28
619 Bidirectional modulation of reward-guided decision making by dopamine
Dias Maile, A. A.; Gründler, T. O. J.; Froböse, M. I.; Kurtenbach, H.; Kaiser, L. F.; Jocham, G.
10.1101/2024.03.27.586793 — neuroscience — Posted on 2024-03-28
621 Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis
Jirouskova, M.; Harant, K.; Cejnar, P.; Ojha, S.; Korelova, K.; Sarnova, L.; Sticova, E.; Mayr, C.; Schiller, H. B.; Gregor, M.
10.1101/2024.03.26.586230 — pathology — Posted on 2024-03-28
622 AutoXAI4Omics: an Automated Explainable AI tool for Omics and tabular data
Strudwick, J.; Gardiner, L.-J.; Denning-James, K.; Haiminen, N.; Evans, A.; Kelly, J.; Madgwick, M.; Utro, F.; Seabolt, E.; Gibson, C.; Bedi, B.; Clayton, D.; Howell, C.; PARIDA, L.; Carrieri, A. P.
10.1101/2024.03.25.586460 — bioinformatics — Posted on 2024-03-28
625 Unravelling the architecture of Major Histocompatibility Complex class II haplotypes in rhesus macaques
de Groot, N.; van der Wiel, M.; Le, N. G.; de Groot, N. G.; Bruijnesteijn, J.; Bontrop, R. E.
10.1101/2024.03.26.586730 — genetics — Posted on 2024-03-28
627 Radioproteomics stratifies molecular response to antifibrotic treatment in pulmonary fibrosis
Lauer, D.; Magnin, C. Y.; Kolly, L.; Wang, H.; Brunner, M.; Chabria, M.; Cereghetti, G. M.; Gabrys, H. S.; Tanadini-Lang, S.; Uldry, A.-C.; Heller, M.; Verleden, S.; Klein, K.; Sarbu, A.-C.; Funke-Chambour, M.; Ebner, L.; Distler, O.; Maurer, B.; Gote-Schniering, J.
10.1101/2024.03.27.586923 — molecular biology — Posted on 2024-03-28
628 Spermidine/spermine N1-acetyltransferase controls tissue-specific regulatory T cell function in chronic inflammation
Neuwirth, T.; Malzl, D.; Knapp, K.; Tsokkou, P.; Kleissl, L.; Redl, A.; Freystaetter, C.; Marella, N.; Kutschat, A. P.; Ponweiser, E.; Haschemi, A.; Seruggia, D.; Menche, J.; Wagner, E. F.; Stary, G.
10.1101/2024.03.25.586519 — immunology — Posted on 2024-03-28
629 Repetitive head impacts induce neuronal loss and neuroinflammation in young athletes
Butler, M. L. M. D.; Pervaiz, N.; Ypsilantis, P.; Wang, Y.; Breda, J. C.; Mazzilli, S. A.; Nicks, R.; Spurlock, E.; Hefti, M. M.; Huber, B. R.; Alvarez, V. E.; Stein, T. D.; Campbell, J. D.; McKee, A. C.; Cherry, J. D.
10.1101/2024.03.26.586815 — neuroscience — Posted on 2024-03-28
631 A Systems Biology Analysis of Chronic Lymphocytic Leukemia
Pozzati, G.; Zhou, J.; Hazan, H.; Klement, G. L.; Siegelmann, H. T.; Rietman, E. A.; Tuszynski, J. A.
10.1101/2024.03.26.586690 — systems biology — Posted on 2024-03-28
632 Quantitative modelling of signaling in aggressive B cell lymphoma unveils conserved core network
Klinger, B.; Rausch, I.; Sieber, A.; Kutz, H.; Kruse, V.; Kirchner, M.; Mertins, P.; Kieser, A.; Bluthgen, N.; Kube, D.
10.1101/2024.03.25.586526 — systems biology — Posted on 2024-03-28
637 The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality
Jinich, A.; Zaveri, A.; DeJesus, M. A.; Flores-Bautista, E.; Almada-Monter, R.; Smith, C. M.; Sassetti, C. M.; Rock, J. M.; Ehrt, S.; Schnappinger, D.; Ioerger, T. R.; Rhee, K. Y.
10.1101/2021.03.05.434127 — microbiology — Posted on 2024-03-28
639 Two separate but interconnected pattern formation systems are required to control body-axis and head-organiser formation in Hydra
Mercker, M.; Tursch, A.; Veerman, F.; Kazarnikov, A.; Höger, S.; Lengfeld, T.; Özbek, S.; Holstein, T. W.; Marciniak-Czochra, A.
10.1101/2021.02.05.429954 — developmental biology — Posted on 2024-03-28
640 Structural basis for recognition of the FLAG-tag by anti-FLAG M2
Beugelink, J. W.; Sweep, E.; Janssen, B. J. C.; Snijder, J.; Pronker, M. F.
10.1101/2024.03.25.586599 — biochemistry — Posted on 2024-03-28
641 Mitochondrial genome variation affects humoral and cell-mediated innate immune responses and infection outcomes
Salminen, T. S.; Vesala, L.; Basikhina, Y.; Kutzer, M.; Tuomela, T.; Lucas, R.; Monteith, K.; Prakash, A.; Tietz, T.; Vale, P. F.
10.1101/2024.03.28.587162 — immunology — Posted on 2024-03-28
642 Orthohantavirus Diversity in Central-East Argentina: Insights from Complete Genomic Sequencing on Phylogenetics, Geographic patterns and Transmission scenarios.
Alonso, D. O.; Kehl, S.; Coelho, R.; Periolo, N.; Poklepovich, T.; Perez-Sautu, U.; Sanchez-Lockhart, M.; Palacios, G. F.; Bellomo, C.; Martinez, V.
10.1101/2024.03.25.586579 — genomics — Posted on 2024-03-28
643 Genome-wide association study elucidates the genetic architecture of manganese tolerance in Brassica napus
Raman, H.; Bai, Z.; McVittie, B.; Mukherjee, S.; Goold, H.; Qiu, Y.; Zhang, Y.; Khin, N. C.; Liu, S.; Delourme, R.; Pogson, B. J.; Balasubramanian, S.; Raman, R.
10.1101/2024.03.27.586972 — plant biology — Posted on 2024-03-28
645 Spatially resolved niche and tumor microenvironmental alterations in gastric cancer peritoneal metastases
Zhao, J. J.; Ong, J. C.-A.; Srivastava, S.; Chia, D. K. A.; Ma, H.; Huang, K. K.; Sheng, T.; Ramnarayanan, K.; Ong, X.; Tay, S. T.; Hagihara, T.; Tan, A. L. K.; Teo, M. C. C.; Tan, Q. X.; Ng, G. W. X.; Tan, J. W.-S.; Ng, M. C. H.; Gwee, Y. X.; Walsh, R.; Shabbir, A.; Kim, G.; Tay, Y. M. S.; Her, Z.; Leoncini, G.; Teh, B. T.; Hong, J. H.; Tay, R. Y. K.; Teo, C. B.; Dings, M. P. G.; Bijlsma, M.; Lum, J. H. Y.; Law, J. H.; Pietrantonio, F.; Blum, S. M.; Laarhoven, H. v.; Klempner, S.; Yong, W. P.; So, J. B. Y.; Chen, Q.; Tan, P.; Sundar, R.
10.1101/2024.03.21.585686 — cancer biology — Posted on 2024-03-28
648 MftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
Gracïa, A. P.; Nikitushkin, V.; Ellerhorst, M.; Vilhena, C.; Klassert, T.; Starick, A.; Siemers, M.; Al-Jammal, W. K.; Vilotijevic, I.; Slevogt, H.; Papenfort, K.; Lackner, G.
10.1101/2024.03.26.586840 — microbiology — Posted on 2024-03-28
649 Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model for Parkinson's disease
Boeck, D.; Wilhelm, M.; Mumenthaler, J.; Carpanese, D. F.; d'Aquin, S.; Cremonesi, A.; Rassi, A.; Haberle, J.; Patriarchi, T.; Schwank, G.
10.1101/2024.03.22.586274 — neuroscience — Posted on 2024-03-28
652 Conserved Lysine in transmembrane helix 5 is key for the inner gating of the LAT transporter BasC
Fort, J.; Nicolas-Arago, A.; Maggi, L.; Martinez-Molledo, M.; Kapiki, D.; Zijlstra, N.; Bodoy, S.; Pardon, E.; Steyaert, J.; Llorca, O.; Orozco, M.; Cordes, T.; Palacin, M.
10.1101/2024.03.26.586791 — biochemistry — Posted on 2024-03-28
653 Developmental stage determines the realized energy landscape for a flight specialist
Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.
10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2024-03-28
654 Fawn bedsite selection by a large ungulate living in a peri-urban area
Conteddu, K.; Wilson, K.; Amin, B.; Chari, S.; Haigh, A.; Griffin, L. L.; Quinn, M.; Ryan, A.; Smith, A. F.; Ciuti, S.
10.1101/2023.08.11.552922 — animal behavior and cognition — Posted on 2024-03-28
657 Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species
Maeda, K.; Sumita, T.; Nishi, O.; Sushida, H.; Higashi, Y.; Nakagawa, H.; Suzuki, T.; Iwao, E.; Fanani, M. Z.; Nishiya, Y.; Iida, Y.
10.1101/2024.03.22.586281 — microbiology — Posted on 2024-03-28
658 Human stem cell derived neurons and astrocytes to detect novel auto-reactive IgG signature in immune-mediated neurological diseases
Mathias, A.; Perriot, S.; Jones, S.; Canales, M.; Bernard-Valnet, R.; Gimenez, M.; Torcida, N.; Oberholster, L.; Hottinger, A. F.; Zekeridou, A.; Theaudin, M.; Pot, C.; Du Pasquier, R.
10.1101/2024.02.26.582006 — neuroscience — Posted on 2024-03-28
659 In-vivo whole-cortex estimation of excitation-inhibition ratio indexes cortical maturation and cognitive ability in youth
Zhang, S.; Larsen, B.; Sydnor, V. J.; Zeng, T.; An, L.; Yan, X.; Kong, R.; Kong, X.; Gur, R. C.; Gur, R. E.; Moore, T. M.; Wolf, D. H.; Holmes, A. J.; Xie, Y.; Zhou, J. H.; Fortier, M. V.; Tan, A. P.; Gluckman, P.; Chong, Y. S.; Meaney, M.; Deco, G.; Satterthwaite, T. D.; Yeo, B. T. T.
10.1101/2023.06.22.546023 — neuroscience — Posted on 2024-03-28
663 CPT1A Mediates Radiation Sensitivity in Colorectal Cancer
Chen, Z.; Yu, L.; Zheng, Z.; Wang, X.; Guo, Q.; Chen, Y.; Zhang, Y.; Zhang, Y.; Xiao, J.; Chen, K.; Fan, H.; Ding, Y.
10.1101/2024.03.26.586752 — cancer biology — Posted on 2024-03-28
665 A high-resolution haplotype pangenome uncovers somatic hybridization, recombination and intercontinental migration in oat crown rust
Henningsen, E.; Lewis, D.; Nazareno, E.; Huang, Y.-F.; Steffenson, B. J.; Boesen, B.; Kianian, S. F.; Stone, E.; Dodds, P.; Sperschneider, J.; Figueroa, M.
10.1101/2024.03.27.583983 — genomics — Posted on 2024-03-27
666 The plant specific cohesin subunit SYN4 contributes to 3D genome organization and activity
Paajanen, P.; Proksch, C.; Krueger, S.; Gorzolka, K.; Stellmach, H.; Ziegler, J.; Romeis, T.; Dodd, A. N.; Bomblies, K.; Handrick, V.
10.1101/2024.03.27.586521 — genetics — Posted on 2024-03-28
667 Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy
Leytens, A.; FERNANDEZ, R. B.; GARCIA, C. J.; ROUBATY, C.; Stumpe, M.; BOYA, P.; Dengjel, J.
10.1101/2024.03.27.586977 — cell biology — Posted on 2024-03-28
668 Molecular basis for condensin enrichment at pericentromeres
Wang, M.; Zou, J.; Spanos, C.; Rappsilber, J.; Marston, A. L.
10.1101/2024.03.27.586992 — cell biology — Posted on 2024-03-28
669 Insulation of ribosomal promoter activity by Fis, H-NS or a divergent promoter within the packed E. coli genome.
Brambilla, E.; Yousuf, M.; Zhang, Q.; Mbemba, G.; Oeuvray, C.; Mektepbayeva, D.; Olliver, A.; Lagomarsino, M. C.; Sclavi, B.
10.1101/2024.03.27.586983 — cell biology — Posted on 2024-03-28
670 FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis
Hugener, J.; Xu, J.; Wettstein, R.; Ioannidi, L.; Velikov, D.; Wollweber, F.; Henggeler, A.; Matos, J.; Pilhofer, M.
10.1101/2024.03.26.586525 — cell biology — Posted on 2024-03-28
671 Mechanism by which Aurora B inhibitors promotes RB and p53-dependent senescence.
Vora, S.; Andrew, A.; Kumar, R. P.; Nazareth, D.; Fernando, M.; Jones, M. J.; He, Y.; Hooper, J.; McMillan, N. A.; Urosevic, J.; Saeh, J.; Travers, J.; Gabrielli, B.
10.1101/2024.03.27.585450 — cell biology — Posted on 2024-03-28
672 Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis
Herlo, R.; Schmidt, J. H.; Rombach, J.; Larsen, A. H.; Stoklund, M.; Perslev, M.; Nielsen, T. T. E.; Andersen, K. A.; Herenbrink, C.; Lycas, M. D.; Ejdrup, A.; Christensen, N.; Christensen, J. P.; Salman, M.; Herborg, F.; Gether, U.; Hauser, A.; Bassereau, P.; Perrais, D.; Madsen, k. L.
10.1101/2024.03.27.587027 — cell biology — Posted on 2024-03-28
674 Tau phosphorylation impedes functionality of protective tau envelopes
Lansky, Z.; Siahaan, V.; Weissova, R.; Lanska, E.; Karhanova, A.; Dostal, V.; Henriot, V.; Janke, C.; Libusova, L.; Braun, M.; Balastik, M.
10.1101/2024.03.25.586522 — cell biology — Posted on 2024-03-28
676 Loss of the Familial Dysautonomia gene Elp1 in cerebellar granule cell progenitors leads to ataxia in mice
Manz, F.; da Silva, P. B. G.; Schouw, M. E.; Lukasch, C.; Bianchini, L.; Sieber, L.; Garcia-Lopez, J.; Ahmad, S. T.; Li, Y.; Lin, H.; Joshi, P.; Spaenig, L.; Rados, M.; Roiuk, M.; Sepp, M.; Zuckermann, M.; Northcott, P. A.; Patrizi, A.; Kutscher, L. M.
10.1101/2024.03.27.586801 — neuroscience — Posted on 2024-03-27
677 Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies
Morderer, D.; Wren, M. C.; Liu, F.; Kouri, N.; Maistrenko, A.; Khalil, B.; Salemi, M. R.; Phinney, B. S.; Dickson, D. W.; Murray, M. E.; Rossoll, W.
10.1101/2024.03.25.585597 — neuroscience — Posted on 2024-03-28
683 The lipid droplet protein DHRS3 is a regulator of melanoma cell state
Johns, E.; Ma, Y.; Louphrasitthipol, P.; Peralta, C.; Hunter, M. V.; Raymond, J. H.; Molina, H.; Goding, C. R.; White, R. M.
10.1101/2024.03.25.586589 — cancer biology — Posted on 2024-03-28
684 A 3D in vitro assay to study combined immune cell infiltration and cytotoxicity
Crawford, A. J.; Johnston, A.; Du, W.; Hanna, E. A.; Schell, D.; Wan, Z.; Chen, T.-H.; Wu, F.; Ren, K.; Lim, Y.; Nair, P. R.; Wirtz, D.
10.1101/2024.03.27.586980 — cancer biology — Posted on 2024-03-28
685 HNF&alpha is a target of the Wnt/beta-catenin pathway and regulates colorectal carcinogenesis
Sang, L.; Bai, W.; Lu, C.; Dong, R.; Hao, Q.; Zhang, Y.; Sun, R.; Shen, J.; Sun, Y.; Sun, J.
10.1101/2024.03.25.586542 — cancer biology — Posted on 2024-03-28
686 Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model
Sakakini, N.; Straver, R.; Azazi, D.; Horton, S. J.; Asby, R.; Richardson, S. E.; Madrigal, P.; Soilleux, E. E.; Bashford-Rogers, R. J. M.; de Ridder, J.; Huntly, B. J. P.
10.1101/2024.03.25.586554 — cancer biology — Posted on 2024-03-28
687 ANP32E drives vulnerability to ATR inhibitors by inducing R-loops-dependent Transcription Replication Conflicts in Triple Negative Breast Cancer
Lago, S.; Poli, V.; Fol, L.; Botteon, M.; Fasciani, A.; Turdo, A.; Gaggianesi, M.; Todaro, M.; Ciani, Y.; D Amato, G.; Demichelis, F.; Zippo, a.
10.1101/2024.03.25.586539 — cancer biology — Posted on 2024-03-28
688 Advancing CAR T-Cell Therapy: Simultaneously Attack Tumor and Immunosuppressive Cells in the Tumor Microenvironment
Luo, Y.; Garavito, E. S.; Brooks, M. M.; Gadd, M. E.; Qie, Y.; Navas, M. J. U.; Hundal, T.; Li, S.; Lopez, A. O.; Jones, V. K.; Lou, Y.; Patel, T.; Dronca, R.; Kharfan-Dabaja, M. A.; Dong, H.; Quinones-Hinojosa, A.; Qin, H.
10.1101/2024.03.25.586653 — cancer biology — Posted on 2024-03-28
691 Androgen deprivation therapy-resistant club cells are linked to myeloid cell-driven immunosuppression in the prostate tumor microenvironment
Kiviaho, A.; Eerola, S. K.; Kallio, H. M. L.; Andersen, M. K.; Spotbeen, X.; Giesen, A.; Parker, C. T. A.; Taavitsainen, S.; Hantula, O.; Marttinen, M.; Hermelo, I.; Ismail, M.; Midtbust, E.; Wess, M.; Devlies, W.; Sharma, A.; Krossa, S.; Hakkinen, T.; Afyounian, E.; Kesseli, J.; Tolonen, T.; Tammela, T. L. J.; Viset, T.; Storkersen, O.; Giskeodegord, G. F.; Rye, M. B.; Murtola, T.; Latonen, L.; Bova, G. S.; Mills, I. G.; Joniau, S.; Swinnen, J. V.; Mirtti, T.; Attard, G.; Claessens, F.; Visakorpi, T.; Rautajoki, K. J.; Tessem, M.-B.; Urbanucci, A.; Nykter, M.
10.1101/2024.03.25.586330 — cancer biology — Posted on 2024-03-28
692 YTHDC1 m6A-dependent and m6A-independent functions converge to preserve DNA damage response.
Elvira-Blazquez, D.; Fernandez-Justel, J.; Arcas, A.; Statello, L.; Goni, E.; Gonzalez, J.; Ricci, B.; Zaccara, S.; Raimondi, I.; Huarte, M.
10.1101/2024.03.25.586632 — cancer biology — Posted on 2024-03-28
694 Hypercholesterolemia-induced impairment in sorafenib functionality is overcome by avasimibe co-treatment
Athavale, D.; Yaduvanshi, H.; Bhati, F. K.; Mayengbam, S. S.; More, T.; Rapole, S.; Bhat, M. K.
10.1101/2024.03.27.586757 — cancer biology — Posted on 2024-03-28
695 A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective Against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy
Wu, B.; Tapadar, S.; Ruan, Z.; Sun, C.; Arnold, R.; Olugbami, J.; Johnston, A.; Arunsi, U.; Gaul, D.; Petros, J.; Kobayashi, T.; Duda, D. G.; Oyelere, A. K.
10.1101/2024.03.27.587062 — cancer biology — Posted on 2024-03-28
696 PTEN and ARID1A haploinsufficiency equip colonic epithelium for oncogenic transformation
Skoufou-Papoutsaki, N.; Adler, S.; Mehmed, S.; Tume, C.; Olpe, C.; Morrissey, E.; Kemp, R.; Girard, A.-C.; Moutin, E. B.; Chilamakuri, C. S. R.; Miller, J. L.; Lindskog, C.; Werle, F.; Marks, K.; Perrone, F.; Zilbauer, M.; Tourigny, D. S.; Winton, D. J.
10.1101/2024.03.27.586939 — cancer biology — Posted on 2024-03-28
697 Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon
Araiza-Olivera, D.; Prudnikova, T. Y.; Uribe-Alvarez, C.; Cai, K. Q.; Franco-Barraza, J.; Dones, J. M.; Raines, R.; Chernoff, J.
10.1101/2024.03.27.587019 — cancer biology — Posted on 2024-03-28
698 Molecular dynamics unveils multiple-site binding of inhibitors with reduced activity on the surface of dihydrofolate reductase
Araki, M.; Ekimoto, T.; Takemura, K.; Matsumoto, S.; Tamura, Y.; Kokubo, H.; Bekker, G.-J.; Yamane, T.; Isaka, Y.; Sagae, Y.; Kamiya, N.; Ikeguchi, M.; Okuno, Y.
10.1101/2024.03.27.586990 — biophysics — Posted on 2024-03-28
700 The Drosophila RNA binding protein Hrp48 binds a specificRNA sequence of the msl-2 mRNA 3' UTR to regulatetranslation
Lomoschitz, A.; Meyer, J.; Guitart, T.; Krepl, M.; Lapouge, K.; Hayn, C.; Schweimer, K.; Simon, B.; Sponer, J.; Gebauer, F.; Hennig, J.
10.1101/2024.03.26.586676 — biophysics — Posted on 2024-03-28
701 Evaluation of intracochlear pressure and distribution during fluid application in cochlea models and human petrous bone
Kim, R.; Riemann, C.; Kilgue, A.; Schleyer, S.; Pfeiffer, C. J.; Scholtz, L.-U.; Schuermann, M.; Todt, I.
10.1101/2024.03.25.586533 — biophysics — Posted on 2024-03-28
703 Open and closed conformations of a sub-80 kDa Chagas vaccine candidate defined by a cryo-EM led integrative approach
Batra, S.; Ragan, T. J.; Frank, A. M.; Kaplan, M.; Lancey, C.; Assadipapari, M.; Ying, C.; Struwe, W. B.; Hesketh, E.; Barfod, L.; Campeotto, I.
10.1101/2024.03.26.586384 — biophysics — Posted on 2024-03-28
705 The Molecular Architecture of the Nuclear Basket
Singh, D.; Soni, N.; Hutchings, J.; Echeverria, I.; Shaikh, F.; Duquette, M.; Suslov, S.; Li, Z.; van Eeuwen, T.; Molloy, K.; Shi, Y.; Wang, J.; Guo, Q.; Chait, B. T.; Fernandez-Martinez, J.; Rout, M. P.; Sali, A.; Villa, E.
10.1101/2024.03.27.587068 — biophysics — Posted on 2024-03-28
707 Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells
Valverde-Mendez, D.; Sunol, A. M.; Bratton, B. P.; Delarue, M.; Hofmann, J. L.; Sheehan, J. P.; Gitai, Z.; Holt, L. J.; Shaevitz, J. W.; Zia, R. N.
10.1101/2024.03.27.587083 — biophysics — Posted on 2024-03-28
708 Development of a generalisable tryptophan-optimised quenchbody biosensor based on a synthetic nanobody library
Cater, J. H.; Elsalamouny, N.; Mansour, G. H.; Hutchinson, S.; Mc Guinness, C.; Mueller, S. H.; Spinks, R. R.; Shanmugam, N.; Pichard-Kostuch, A.; Ghodke, H.; Ribezzi-Crivellari, M.; Yu, H.; van Oijen, A. M.; Griffiths, A. D.; Spenkelink, L. M.
10.1101/2024.03.27.582625 — bioengineering — Posted on 2024-03-27
710 Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes
Ray, P.; Sedigh, A.; Confeld, M.; Alhalhooly, L.; Iduoku, K.; Casanola-Martin, G.; Pham-The, H.; Rasulev, B.; Choi, Y.; Yang, Z.; Mallik, S.; Quadir, M.
10.1101/2024.03.26.585429 — bioengineering — Posted on 2024-03-27
711 Targeting protein-ligand neosurfaces using a generalizable deep learning approach
Marchand, A.; Buckley, S.; Schneuing, A.; Pacesa, M.; Gainza, P.; Elizarova, E.; Neeser, R. M.; Lee, P.-W.; Reymond, L.; Elia, M.; Scheller, L.; Georgeon, S.; Schmidt, J.; Schwaller, P.; Maerkl, S. J.; Bronstein, M.; Correia, B. E.
10.1101/2024.03.25.585721 — biochemistry — Posted on 2024-03-28
714 The structure of the R2T complex reveals a different architecture of the related HSP90 co-chaperones R2T and R2TP
Palacios-Abella, A.; Lopez-Perrote, A.; Boskovic, J.; Fonseca, S.; Urbez, C.; Rubio, V.; Llorca, O.; Alabadi, D.
10.1101/2024.03.27.587014 — biochemistry — Posted on 2024-03-28
715 Intron-loss in Kinetoplastea correlates with a non-functional EJC and loss of NMD factors
Gabiatti, B. P.; Freire, E. R.; Odenwald, J.; Holetz, F.; Carrington, M.; Kramer, S.; Zoltner, M.
10.1101/2024.03.25.586568 — biochemistry — Posted on 2024-03-28
716 Identification and characterization of nanobodies acting as molecular chaperones for glucocerebrosidase through a novel allosteric mechanism
Dal Maso, T.; Sinisgalli, C.; Zilio, G.; Tessari, I.; Pardon, E.; Steyaert, J.; Ballet, S.; Greggio, E.; Versees, W.; Plotegher, N.
10.1101/2024.03.25.586126 — biochemistry — Posted on 2024-03-28
717 Trafficking of Connexin36 (Cx36) in the early secretory pathway
Tetenborg, S.; Ariakia, F.; Martinez-Soler, E.; Shihabeddin, E.; Lazart, I. C.; Miller, A. C.; O'Brien, J.
10.1101/2024.03.25.586643 — biochemistry — Posted on 2024-03-28
720 Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients
Azimi, M.; Cho, S.; Bozkurt, E.; McDonough, E.; Kisakol, B.; Matveeva, A.; Salvucci, M.; Dussmann, H.; Firat, C.; Urganci, N.; Shia, J.; McDade, S.; Longley, D. B.; Ginty, F.; Prehn, J. H. M.
10.1101/2024.01.30.577720 — cancer biology — Posted on 2024-03-28
721 Biolearn, an open-source library for biomarkers of aging
Ying, K.; Paulson, S.; Eames, A.; Li, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Gobel, D.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.
10.1101/2023.12.02.569722 — bioinformatics — Posted on 2024-03-28
722 Bioenergetic mapping of 'healthy microbiomes' via compound processing potential imprinted in gut and soil metagenomes
Liddicoat, C.; Edwards, R. A.; Roach, M. J.; Robinson, J. M.; Wallace, K. J.; Barnes, A. D.; Brame, J.; Heintz-Buschart, A.; Cavagnaro, T. R.; Dinsdale, E. A.; Doane, M. P.; Eisenhauer, N.; Mitchell, G.; Rai, B.; Ramesh, S.; Breed, M. F.
10.1101/2023.11.05.565728 — bioinformatics — Posted on 2024-03-28
723 Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data
Hall, M. B.; Wick, R. R.; Judd, L. M.; Nguyen, A. N. T.; Steinig, E. J.; Xie, O.; Davies, M. R.; Seemann, T.; Stinear, T. P.; Coin, L. J. M.
10.1101/2024.03.15.585313 — bioinformatics — Posted on 2024-03-28
724 Genome-wide co-essentiality analysis in Mycobacterium tuberculosis reveals an itaconate defense enzyme module
Jinich, A.; Nazia, S. Z.; Tellez, A. V.; Wu, A. M.; Almada-Monter, R.; Smith, C. M.; Rhee, K. Y.
10.1101/2022.09.27.509804 — microbiology — Posted on 2024-03-28
726 Small extracellular vesicles promote stiffness-mediated metastasis
Sneider, A.; Liu, Y.; Starich, B.; Du, W.; Marar, C.; Faqih, N.; Ciotti, G. E.; Kim, J. H.; Krishnan, S.; Ibrahim, S.; Igboko, M.; Locke, A.; Lewis, D. M.; Hong, H.; Karl, M.; Vij, R.; Russo, G. C.; Nair, P. R.; Gomez-de-Mariscal, E.; Habibi, M.; Munoz-Barrutia, A.; Gu, L.; Eisinger-Mathason, T. S. K.; Wirtz, D.
10.1101/2023.07.01.545937 — cancer biology — Posted on 2024-03-28
729 Predictive modeling provides insight into the clinical heterogeneity associated with TARS1 loss-of-function mutations
Meyer-Schuman, R.; Cale, A. R.; Pierluissi, J. A.; Jonatzke, K. E.; Park, Y. N.; Lenk, G. M.; Oprescu, S. N.; Grachtchouk, M. A.; Dlugosz, A. A.; Beg, A. A.; Meisler, M. H.; Antonellis, A.
10.1101/2024.03.25.586600 — genetics — Posted on 2024-03-27
732 Analysis of gliomas DNA methylation: Assessment of pre-analytical variables.
Bomsztyk, K.; Mar, D.; Denisenko, O.; Powell, S.; Vishnoi, M.; Delegard, J.; Patel, A.; Ellenbogen, R.; Ramakrishna, R.; Rostomily, R.
10.1101/2024.03.26.586350 — molecular biology — Posted on 2024-03-27
735 Global variation in prior exposure shapes antibody neutralization profiles of SARS-CoV-2 variants up to BA.2.86
Turner, S.; Amirthalingam, G.; Bailey, D.; Barouch, D. H.; Bewley, K. R.; Brown, K.; Cao, Y. R.; Chan, Y.-W.; Charlton, S.; DOVE consortium, ; Coombes, N. S.; Hallis, B.; Ho, D. D.; Jian, F.; Lasrado, N.; Lassauniere, R.; Lihong, L.; Montefiori, D. C.; Moss, P.; Newman, J.; Parry, H.; Polacek Strandh, C.; Rasmussen, M.; Shao, F.; Shen, X.; Thakur, N.; Thomson, E. C.; Wang, J.; Wang, P.; Wang, Q. C.; Willett, B. J.; Yisimayi, A.; Smith, D. J.
10.1101/2024.03.27.586820 — immunology — Posted on 2024-03-27
739 Molecular Basis for RNA Cytidine Acetylation by NAT10
Zhou, M.; Gamage, S. T.; Tran, K.; Bartee, D.; Wei, X.; Yin, B.; Berger, S.; Meier, J. L.; Marmorstein, R.
10.1101/2024.03.27.587050 — biophysics — Posted on 2024-03-27
742 Structural basis for recognition of the FLAG-1 tag by anti-FLAG M2
Beugelink, J. W.; Sweep, E.; Janssen, B. J. C.; Snijder, J.; Pronker, M. F.
10.1101/2024.03.25.586599 — biochemistry — Posted on 2024-03-27
743 Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation
Niedner-Boblenz, A.; Monecke, T.; Hennig, J.; Klostermann, M.; Hofweber, M.; Davydova, E.; Gerber, A. P.; Anosova, I.; Mayer, W.; Mueller, M.; Heym, R.; Janowski, R.; Paillart, J.-C.; Dormann, D.; Zarnack, K.; Sattler, M.; Niessing, D.
10.1101/2024.03.27.586925 — biochemistry — Posted on 2024-03-27
744 A benchmarked, high-efficiency prime editing platform for multiplexed dropout screening
Cirincione, A.; Simpson, D.; Ravisankar, P.; Solley, S. C.; Yan, J.; Singh, M.; Adamson, B.
10.1101/2024.03.25.585978 — genomics — Posted on 2024-03-27
746 Transcript-specific enrichment enables profiling rare cell states via scRNA-seq
Abay, T.; Stickels, R. R.; Takizawa, M. T.; Nalbant, B. N.; Hsieh, Y.-H.; Hwang, S.; Snopkowski, C.; Yu, K. K. H.; Abou-Mrad, Z.; Tabar, V.; Ludwig, L. S.; Chaligne, R.; Satpathy, A. T.; Lareau, C. A.
10.1101/2024.03.27.587039 — genomics — Posted on 2024-03-27
747 Metal fluorides - multi-functional tools for the study of phosphoryl transfer enzymes
Pellegrini, E.; Juyoux, P.; von Velsen, J.; Baxter, N.; Jin, Y.; Dannatt, H.; Cliff, M.; Waltho, J.; Bowler, M. W.
10.1101/2024.03.25.586559 — molecular biology — Posted on 2024-03-27
750 Circular RNA aptamers ameliorate AD-relevant phenotypes by targeting PKR
Feng, X.; Jiang, B.-W.; Zhai, S.-N.; Liu, C.-X.; Wu, H.; Zhu, B.-Q.; Wei, M.-Y.; Wei, J.; Yang, L.; Chen, L.-L.
10.1101/2024.03.27.583257 — molecular biology — Posted on 2024-03-27
751 Outer membrane vesicles can contribute to cellulose degradation in Teredinibacter turnerae, a cultivable intracellular endosymbiont of shipworms
Gasser, M. T.; Liu, A.; Altamia, M. A.; Bresinger, B.; Brewer, S. L.; Flatau, R.; Hancock, E.; Preheim, S. P.; Filone, C. M.; Distel, D. L.
10.1101/2024.03.27.587001 — microbiology — Posted on 2024-03-27
752 The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication
Baker, P. J.; Bohrer, A. C.; Castro, E.; Amaral, E. P.; Snow-Smith, M.; Torres-Juarez, F.; Gould, S. T.; Queiroz, A. T.; Fukutani, E. R.; Jordan, C. M.; Khillan, J. S.; Cho, K.; Barber, D. L.; Andrade, B. B.; Johnson, R. F.; Hilligan, K. L.; Mayer-Barber, K. D.
10.1101/2024.03.27.586885 — immunology — Posted on 2024-03-27
753 Fast burst fraction transients convey information independent of the firing rate
Naud, R.; Wang, X.; Friedenberger, Z.; Payeur, A.; Shin, J. N.; Beique, J.-C.; Richards, B.; Drüke, M.; Larkum, M.; Doron, G.
10.1101/2022.10.07.511138 — neuroscience — Posted on 2024-03-27
754 AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer's disease
Kim, Y. S.; CHOI, S.-H.; Kim, K.-Y.; Navia Pelaez, J. M.; Perkins, G. A.; Choi, S.; Nazarenkov, N.; Kim, J.; Ju, W.; Rissman, R. A.; Ellisman, M. H.; Miller, Y. I.
10.1101/2024.02.16.580751 — neuroscience — Posted on 2024-03-27
756 ComPRePS: An Automated Cloud-based Image Analysis tool to democratize AI in Digital Pathology
Mimar, S.; Paul, A. S.; Lucarelli, N.; Boarder, S.; Santo, B. A.; Naglah, A.; Barisoni, L.; Hodgin, J.; Rosenberg, A.; Clapp, W.; Sarder, P.; for the Kidney Precision Medicine Project,
10.1101/2024.03.21.586102 — pathology — Posted on 2024-03-27
757 Cancer cell - fibroblast crosstalk via HB-EGF/EGFR/MEK signalling promotes macrophage recruitment in squamous cell carcinoma
Giangreco, G.; Rullan, A.; Naito, Y.; Biwas, D.; Liu, Y.-H.; Hooper, S.; Nenclares, P.; Bhide, S.; Cheang, M.; Chakravarty, P.; Hirata, E.; Swanton, C.; Melcher, A.; Harrington, K.; Sahai, E.
10.1101/2023.07.13.548733 — cancer biology — Posted on 2024-03-27
762 Carbohydrate-active enzymes from Akkermansia muciniphila breakdown mucin O-glycans to completion
Crouch, L. I.; Bakshani, C. R.; Ojuri, T. O.; Pilgaard, B.; Holck, J.; McInnes, R.; Zakhour, M.; Kerouedan, M.; Newton, E.; Bolam, D. N.
10.1101/2024.03.27.586211 — biochemistry — Posted on 2024-03-27
764 Simulating animal movement trajectories from temporally dynamic step selection functions
Forrest, S. W.; Pagendam, D.; Bode, M.; Drovandi, C.; Potts, J. R.; Perry, J.; Vanderduys, E.; Hoskins, A. J.
10.1101/2024.03.19.585696 — ecology — Posted on 2024-03-27
766 Towards Targeted Protein Degradation in Escherichia coli - depletion of the essential GroEL protein using CLIPPERs.
Izert-Nowakowska, M. A.; Klimecka, M. M.; Antosiewicz, A.; Wroblewski, K.; Bandyra, K. J.; Goral, T. K.; Kmiecik, S.; Serwa, R. A.; Gorna, M. W.
10.1101/2024.02.29.582761 — molecular biology — Posted on 2024-03-27
769 In vivo Assembly of Bacterial Partition Condensates on Supercoiled and Linear DNA
Sekkouri Alaoui, H.; Quebre, V.; Delimi, L.; Rech, J.; Debaugny-Diaz, R.; Labourdette, D.; Campos, M.; Cornet, F.; Walter, J.-C.; Bouet, J.-Y.
10.1101/2024.03.26.585537 — molecular biology — Posted on 2024-03-27
772 Altruistic feeding and cell-cell signaling during bacterial differentiation actively enhance phenotypic heterogeneity
Updegrove, T. B.; Delerue, T.; Anantharaman, V.; Cho, H.; Chan, C.; Nipper, T.; Choo-Wosoba, H.; Jenkins, L.; Zhang, L.; Su, Y.; Shroff, H.; Chen, J.; Bewley, C.; Aravind, L.; Ramamurthi, K. S.
10.1101/2024.03.27.587046 — microbiology — Posted on 2024-03-27
774 Identifying immune signatures of common exposures through co-occurrence of T-cell receptors in tens of thousands of donors
May, D. H.; Woodhouse, S.; Zahid, H. J.; Elyanow, R.; Doroschak, K.; Noakes, M. T.; Taniguchi, R.; Yang, Z.; Grino, J.; Byron, R.; Oaks, J.; Sherwood, A.; Greissl, J.; Chen-Harris, H.; Howie, B.; Robins, H. S.
10.1101/2024.03.26.583354 — immunology — Posted on 2024-03-27
775 Separating cognitive and motor processes in the behaving mouse
Hasnain, M. A.; Birnbaum, J. E.; Nunez, J. L. U.; Hartman, E.; Chandrasekaran, C.; Economo, M. N.
10.1101/2023.08.23.554474 — neuroscience — Posted on 2024-03-27
776 Cyanamide-inducible expression of homing nuclease I-SceI for iterative genome engineering and parallel promoter characterisation in Saccharomyces cerevisiae
McDonnell, L.; Evans, S.; Lu, Z.; Suchoronczak, M.; Leighton, J.; Ordeniza, E.; Ritchie, B.; Valado, N.; Walsh, N.; Antoney, J. P.; Wang, C.; Scott, C.; Speight, R.; Vickers, C.; Peng, B.
10.1101/2024.03.26.586389 — synthetic biology — Posted on 2024-03-27
778 Exploring structural diversity across the protein universe with The Encyclopedia of Domains
Lau, A. M. C.; Bordin, N.; Kandathil, S. M.; Sillitoe, I.; Waman, V. P.; Wells, J.; Orengo, C.; Jones, D. T.
10.1101/2024.03.18.585509 — bioinformatics — Posted on 2024-03-27
780 How do Large Language Models understand Genes and Cells
Fang, C.; Wang, Y.; Song, Y.; Long, Q.; Lu, W.; Chen, L.; Wang, P.; Feng, G.; Zhou, Y.; Li, X.
10.1101/2024.03.23.586383 — bioinformatics — Posted on 2024-03-27
781 CCQM-P199b: Interlaboratory comparability study of SARS-CoV-2 RNA copy number quantification
Devonshire, A. S.; Busby, E. J.; Jones, G. M.; O'Sullivan, D. M.; Fernandez-Gonzalez, A.; Hernandez-Hernandez, L.; Dai, X.; Dong, L.; Niu, C.; Xie, J.; Wang, X.; Qiao, X.; Fang, X.; Morris, C.; Almond, N.; Cleveland, M. H.; Vallone, P. M.; Castro Galvan, E.; Perez Urquiza, M.; Guadalupe Herrera Lopez, M.; Khan, A. S.; Fuentes, S. M.; Emerson Leguizamon, J.; Luis Davila Gonzalez, S.; Felipe Leon Torres, A.; Folgueras-Flatschart, A. V.; Neves de Medeiros, M.; Marcos Saraiva, A.; Becht Flatschart, R.; Divieto, C.; Pegoraro, M.; Zucco, M.; Revel, L.; Mazzara, M.; Corbisier, P.; Buttinger, G.; Yang
10.1101/2024.03.27.584106 — molecular biology — Posted on 2024-03-27
782 In-silico docking platform with serine protease inhibitor (SERPIN) structures identifies host cysteine protease targets with significance for SARS-CoV-2
Rodriguez Galvan, J. J.; de Vries, M.; Belblidia, S.; Fisher, A.; Prescott, R. A.; Crosse, K. M.; Mangel, W. F.; Duerr, R.; Dittmann, M.
10.1101/2022.11.18.517133 — microbiology — Posted on 2024-03-27
783 Virological characteristics of SARS-CoV-2 Omicron BA.5.2.48
Wang, W.; Jin, Q.; Liu, R.; Zeng, W.; Zhu, P.; Li, T.; Wang, T.; Xiang, H.; Zhang, H.; Chen, Q.; Gao, Y.; Lai, Y.; Yan, F.; Xia, X.; Li, J.; Wang, X.; Gao, Y.
10.1101/2024.03.26.586802 — microbiology — Posted on 2024-03-27
784 TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders
Debeuf, N.; Lameire, S.; Vanheerswynghels, M.; Deckers, J.; De Wolf, C.; Toussaint, W.; Verbeke, R.; Verstaen, K.; Hammad, H.; Vanhee, S.; Lambrecht, B. N.
10.1101/2024.03.27.586931 — immunology — Posted on 2024-03-27
785 Intercellular Signaling Pathways as Therapeutic Targets for Vascular Dementia Repair
Tian, M.; Kawaguchi, R.; Shen, Y.; Machnicki, M.; Villegas, N. G.; Cooper, D. R.; Montgomery, N.; Haring, J.; Lan, R.; Yuan, A. H.; Williams, C. K.; Magaki, S.; Vinters, H. V.; Zhang, Y.; De Biase, L. M.; Silva, A. J.; Carmichael, S. T.
10.1101/2024.03.24.585301 — neuroscience — Posted on 2024-03-27
786 The Effects of Acute Coordinative vs. Acute Endurance Exercise on the Cortisol Concentration
Budde, H.; Wegner, M.; Ahrens, C.; Velasques, B.; Ribeiro, P.; Machado, S.; Mueller-Alcazar, A.
10.1101/2024.03.25.586687 — physiology — Posted on 2024-03-27
788 Conditions for the co-existence of promoter and gene-body condensates
Changiarath, A.; Michels, J.; Rodriguez, R. H.; Hanson, S. M.; Schmid, F.; Padeken, J.; Stelzl, L. S.
10.1101/2024.03.16.585180 — biophysics — Posted on 2024-03-27
789 Crosslinking by ZapD drives the assembly of short FtsZ filaments into toroidal structures in solution
Merino-Salomon, A.; Schneider, J.; Babl, L.; Krohn, J.-H.; Sobrinos-Sanguino, M.; Schäfer, T.; Luque-Ortega, J. R.; Alfonso, C.; Jimenez, M.; Jasnin, M.; Schwille, P.; Rivas, G.
10.1101/2023.01.12.523557 — biochemistry — Posted on 2024-03-27
792 Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction
Bayer, H.; Hassell, J. E.; Oleksiak, C. R.; Garcia, G. M.; Vaughan, H.; Juliano, V. A. L.; Maren, S.
10.1101/2024.03.23.586410 — neuroscience — Posted on 2024-03-27
794 Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life
Corvilain, P.; Wens, V.; Bourguignon, M.; Capparini, C.; Fourdin, L.; Ferez, M.; Feys, O.; De Tiege, X.; Bertels, J.
10.1101/2023.10.28.564455 — neuroscience — Posted on 2024-03-27
795 Human HPSE2 gene transfer ameliorates bladder pathophysiology in a mutant mouse model of urofacial syndrome.
Lopes, F. M.; Grenier, C.; Jarvis, B. W.; Al Mahdy, S.; Lene-Mckay, A.; Gurney, A. M.; Newman, W. G.; Waddington, S. N.; Woolf, A. S.; Roberts, N. A.
10.1101/2023.07.03.547034 — neuroscience — Posted on 2024-03-27
798 Aging-associated weakening of the action potential in fast-spiking interneurons in the human neocortex
Szegedi, V.; Tiszlavicz, A.; Furdan, S.; Douida, A.; Bakos, E.; Barzo, P.; Tamas, G.; Szucs, A.; Lamsa, K.
10.1101/2024.03.24.586453 — neuroscience — Posted on 2024-03-27
799 PKHD1L1 is required for stereocilia bundle maintenance, durable hearing function and resilience to noise exposure.
Strelkova, O. S.; Osgood, R. T.; Tian, C. J.; Zhang, X.; Hale, E.; De-la-Torre, P.; Hathaway, D. M.; Indzhykulian, A. A.
10.1101/2024.02.29.582786 — neuroscience — Posted on 2024-03-27
803 Enhanced extracellular matrix remodeling due to embedded spheroid fluidization
Zhang, T.; Ameen, S.; Ghosh, S.; Kim, K.; Thanh, M.; Patteson, A. E.; Wu, M.; Schwarz, J. M.
10.1101/2024.03.25.586590 — biophysics — Posted on 2024-03-27
804 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening
Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.
10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-27
806 Application of chimeric antigens to paper-based diagnostics for detection of West Nile virus infections of Crocodylus porosus: a novel animal test case
Johnston, R. A.; Habarugira, G.; Harrison, J. J.; Isberg, S. R.; Moran, J.; Morgan, M.; Davis, S. S.; Melville, L. F.; Howard, C. B.; Henry, C. S.; Macdonald, J.; Bielefeldt-Ohmann, H. A.; Hall, R. A.; Hobson-Peters, J.
10.1101/2024.03.24.586480 — biochemistry — Posted on 2024-03-27
807 Multifaceted roles of cohesin in regulating transcriptional loops
Kim, M.; Wang, P.; Clow, P.; Chien, I.; Wang, X.; Peng, J.; Chai, H.; Liu, X.; Lee, B.; Ngan, C. Y.; Yue, F.; Milenkovic, O.; Chuang, J. H.; Wei, C.-L.; Casellas, R.; Cheng, A.; Ruan, Y.
10.1101/2024.03.25.586715 — genomics — Posted on 2024-03-27
808 Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells
Tarbier, M.; Mackowiak, S. D.; Sekar, V.; Bonath, F.; Yapar, E.; Fromm, B.; Faridani, O. R.; Biryukova, I.; Friedländer, M. R.
10.1101/2024.03.24.586475 — genomics — Posted on 2024-03-27
809 Mutation of GmDMP genes triggers haploid induction in soybean
Zhong, Y.; Yang, M.; Cheng, D.; Liu, J.; Han, Q.; Liu, C.; Qi, X.; Yan, T.; Teng, L.; Xv, C.; Hou, J.; Sun, L.; Liu, C.; Chen, Q.; Chen, S.
10.1101/2024.03.24.585499 — genetics — Posted on 2024-03-27
811 EVOLUTIONARY CO-OPTION OF AN ANCESTRAL CLOACAL REGULATORY LANDSCAPE DURING THE EMERGENCE OF DIGITS AND GENITALS
Hintermann, A.; Bolt, C. C.; Hawkins, M. B.; Valentin, G.; Lopez-Delisle, L.; Gitto, S.; Gomez, P. B.; Mascrez, B.; Mansour, T. A.; Nakamura, T.; Harris, M. P.; Shubin, N. H.; Duboule, D.
10.1101/2024.03.24.586442 — evolutionary biology — Posted on 2024-03-27
813 : A tool for modelling ecosystem resilience
Klimes, A.; Chipperfield, J. D.; Topper, J. P.; Macias-Fauria, M.; Spiegel, M.; Vandvik, V.; Velle, L. G.; Seddon, A. W. R.
10.1101/2024.03.23.586419 — ecology — Posted on 2024-03-27
815 Neuronal activation affects the organization and protein composition of the nuclear speckles
Szczepankiewicz, A. A.; Parobczak, K.; Zareba-Koziol, M.; Ruszczycki, B.; Bijata, M.; Trzaskoma, P.; Hajnowski, G.; Holm-Kaczmarek, D.; Wlodarczyk, J.; Wilczynski, G. M.; Redowicz, M. J.; Magalska, A.
10.1101/2024.03.25.586583 — cell biology — Posted on 2024-03-27
816 mTOR activation induces endolysosomal remodeling and unconventional secretion of IL-32 via exosomes in inflammatory reactive astrocytes
Leng, K.; Rooney, B.; McCarthy, F.; Xia, W.; Rose, I. V. L.; Bax, S.; Chin, M. Y.; Fathi, S.; Herrington, K. A.; Leonetti, M.; Kao, A. W.; Fancy, S. P. J.; Elias, J. E.; Kampmann, M.
10.1101/2021.09.11.459904 — cell biology — Posted on 2024-03-27
819 Enteric glutamatergic interneurons regulate intestinal motility
Hamnett, R.; Bendrick, J. L.; Robertson, K.; Zhao, E. T.; Kaltschmidt, J. A.
10.1101/2024.03.24.586153 — neuroscience — Posted on 2024-03-27
821 Ageing impacts basic auditory and timing processing
Criscuolo, A.; Schwartze, M.; Bonetti, L.; Kotz, S. A.
10.1101/2024.03.24.586049 — neuroscience — Posted on 2024-03-27
822 Mapping Serotonergic Dynamics using Drug-Modulated Molecular Connectivity
Ionescu, T. M.; Amend, M.; Hafiz, R.; Maurer, A.; Biswal, B. B.; Wehrl, H. F.; Herfert, K.
10.1101/2024.02.08.579462 — neuroscience — Posted on 2024-03-27
824 The regulatory architecture of the primed pluripotent cell state
Li, B. I.; Alvarez, M. J.; Zhao, H.; Chirathivat, N.; Califano, A.; Shen, M. M.
10.1101/2024.03.25.586622 — systems biology — Posted on 2024-03-27
825 Nuclear actin and DNA replication stress regulate the recruitment of human telomerase to telomeres
Harman, A.; Kartawinata, M.; Maroun, N. M.; Nguyen, D. R.; Hughes, W. E.; Winardi, K.; Cesare, A. J.; Lamm, N.; Bryan, T. M.
10.1101/2024.03.25.586711 — cancer biology — Posted on 2024-03-27
826 Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma
Dantzer, C.; Vache, J.; Brunel, A.; Mahouche, I.; Raymond, A.-A.; Dupuy, J.-W.; Petrel, M.; Bioulac-Sage, P.; Perrais, D.; Dugot-Senant, N.; Verdier-Sage, M.; Bessette, B.; Billottet, C.; Moreau, V.
10.1101/2023.10.24.563805 — cancer biology — Posted on 2024-03-27
830 Multi-omics characterization of highly enriched human plasma extracellular vesicles.
Su, H.; Fowler, C.; Masters, C. L.; Barnham, K. J.; Reid, G. E.; Vella, L. J.
10.1101/2024.03.25.586695 — biochemistry — Posted on 2024-03-27
832 Complete telomere-to-telomere assemblies of two sorghum genomes to guide biological discovery
Wei, C.; Gao, L.; Xiao, R.; Wang, Y.; Chen, B.; Zou, W.; Li, J.; Emma, M.; David, J.; Tao, Y.
10.1101/2024.03.24.586445 — genomics — Posted on 2024-03-27
839 Nutrient Sensing Receptor GPRC6A Regulates mTORC1 Signaling and Tau Biology
Ma, C.; Campbell, K.; Kovalenko, A.; Sandusky-Beltran, L. A.; Liang, H.; Hunt, J. B.; Calahatian, J.; Kallupurackal, M.; Pandey, S.; Vasisht, M.; Walter, M.; Quadri, Z.; Michalski, C.; Fahnestock, M.; Papangelis, A.; Pedersen, D. S.; Ulven, T.; Nash, K.; Selenica, M.-L. B.; Morgan, D.; Bickford, P. C.; Lee, D. C.
10.1101/2024.03.24.586459 — neuroscience — Posted on 2024-03-27
846 Root surface treatment for delayed replantation of avulsed teeth in animal models: a systematic review
Huaman, S. D.; Vilela, M. M.; Nelson-Filho, P.; De-Rossi, A.; Queiroz, A. M.; Paula-Silva, F. W. G.
10.1101/2024.03.24.586399 — pharmacology and toxicology — Posted on 2024-03-27
847 Patient-derived response estimates from zero-passage organoids of luminal breast cancer
Przanowska, R.; Labban, N.; Przanowski, P.; Hawes, R.; Atkins, K.; Showalter, S.; Janes, K.
10.1101/2024.03.24.586432 — cancer biology — Posted on 2024-03-27
848 Fast volumetric fluorescence lifetime imaging of multicellular systems using single-objective light-sheet microscopy
Dunsing-Eichenauer, V.; Hummert, J.; Chardes, C.; Schönau, T.; Guignard, L.; Galland, R.; Grenci, G.; Tillmann, M.; Koberling, F.; Nock, C.; Sibarita, J.-B.; Viasnoff, V.; Antolovic, I. M.; Erdmann, R.; Lenne, P.-F.
10.1101/2024.03.24.586451 — biophysics — Posted on 2024-03-27
850 BetaAlign: a deep learning approach for multiple sequence alignment
Dotan, E.; Wygoda, E.; Ecker, N.; Alburquerque, M.; Avram, O.; Belinkov, Y.; Pupko, T.
10.1101/2024.03.24.586462 — bioinformatics — Posted on 2024-03-27
853 DUAL ACTION ELECTROCHEMICAL BANDAGE OPERATED by a PROGRAMMABLE MULTIMODAL WEARABLE POTENTIOSTAT
Bozyel, I.; Fleming, D.; Kim, W.-J.; Rosern, P. F.; Gelston, S.; Ozdemir, D.; Ay, S. U.; Patel, R.; Beyenal, H.
10.1101/2024.03.22.586346 — bioengineering — Posted on 2024-03-27
855 Five millennia of mitochondrial introgression in Atlantic bluefin tuna identified using ancient DNA
Eriksen, E. F.; Andrews, A. J.; Nielsen, S. V.; Persson, P.; Malca, E.; Onar, V.; Aniceti, V.; Piques, G.; Piattoni, F.; Fontani, F.; Wiech, M.; Ferter, K.; Kersten, O.; Ferrari, G.; Cariani, A.; Tinti, F.; Cilli, E.; Atmore, L. M.; Star, B.
10.1101/2024.03.24.586294 — evolutionary biology — Posted on 2024-03-27
856 Thermal tolerance of mosquito eggs is associated with urban adaptation and human interactions
Chakraborty, S.; Zigmond, E.; Shah, S.; Sylla, M.; Akorli, J.; Otoo, S.; Rose, N. H.; McBride, C. S.; Armbruster, P. A.; Benoit, J. B.
10.1101/2024.03.22.586322 — ecology — Posted on 2024-03-27
860 Coordinated regulation of osmotic imbalance by c-di-AMP shapes beta-lactam tolerance in Group B Streptococcus
Brissac, T.; Guyonnet, C.; Sadouni, A.; Hernandez Montoya, A.; Jacquemet, E.; Legendre, R.; Sismeiro, O.; Trieu-Cuot, P.; Lanotte, P.; Tazi, A.; Firon, A.
10.1101/2024.03.27.586946 — microbiology — Posted on 2024-03-27
862 Primate V2 Receptive Fields Derived from Anatomically Identified Large-Scale V1 Inputs
Hassanpour, M. S.; Merlin, S.; Frederick Federer, F.; Zaidi, Q.; Angelucci, A.
10.1101/2024.03.22.586002 — neuroscience — Posted on 2024-03-27
866 MOS4-Associated Complex subunits 3A and 3B modulate FLM splicing to repress photoperiod-dependent floral transition
Huang, Y.-W.; Tseng, C.-Y.; Tu, Y.-T.; Hsieh, H.-Y.; Wang, Y.-S.; Chen, Y.-Z.; Ly, Y.-T.; Tu, S.-L.; Lee, C.-M.
10.1101/2024.03.26.586198 — plant biology — Posted on 2024-03-27
867 Pannexin 1 Channels Control Cardiomyocyte Metabolism and Neutrophil Recruitment During Non-Ischemic Heart Failure
Pavelec, C. M.; Young, A.; Luviano, H. L.; Orrell, E. E.; Szagdaj, A.; Poudel, N.; Wolpe, A. G.; Thomas, S. H.; Yeudall, S.; Upchurch, C.; Okusa, M. D.; Isakson, B. E.; Wolf, M. J.; Leitinger, N.
10.1101/2023.12.29.573679 — physiology — Posted on 2024-03-27
868 Self-perceived middle-distance race pace is faster in Advanced Footwear Technology spikes
Bertschy, M.; Rodrigo Carranza, V.; Wilkie, E. W. C.; Healey, L. A.; Noble, J.; Albert, W. J.; Hoogkamer, W.
10.1101/2023.10.25.564056 — physiology — Posted on 2024-03-27
869 ChemPrint: An AI-Driven Framework for Enhanced Drug Discovery
Umansky, T.; Ramesh, N.; Woods, V.; Russell, S. M.; Smith, D. M.; Haders, D.
10.1101/2024.03.22.586314 — bioinformatics — Posted on 2024-03-27
871 mm2-gb: GPU Accelerated Minimap2 for Long Read DNA Mapping
Dong, J.; Liu, X.; Sadasivan, H.; Sitaraman, S.; Narayanasamy, S.
10.1101/2024.03.23.586366 — genomics — Posted on 2024-03-27
872 Acute multi-level response to defective de novo chromatin assembly in S-phase
Dreyer, J.; Ricci, G.; van den Berg, J.; Bhardwaj, V.; Funk, J.; Armstrong, C.; van Batenburg, V.; Sine, C.; Vaninsberghe, M. A.; Marsman, R.; Mandemaker, I. K.; di Sanzo, S.; Costantini, J.; Manzo, S.; Biran, A.; Burny, C.; Voelker-Albert, M.; Groth, A.; Spencer, S. L.; van Oudenaarden, A.; Mattiroli, F.
10.1101/2024.03.22.586291 — cell biology — Posted on 2024-03-27
873 A panel of phenotypically and genotypically diverse bioluminescent: fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research
Olmo, F.; Jayawardhana, S.; Khan, A. A.; Langston, H. C.; Francisco, A. F.; Atherton, R. A.; Ward, A. I.; Taylor, M. C.; Kelly, J. M.; Lewis, M. D.
10.1101/2024.03.27.586912 — microbiology — Posted on 2024-03-27
875 Bacterial profiles of the oral, vaginal, and rectal mucosa and colostrum of periparturient sows
Piirainen, V.; Konig, E.; Husso, A.; Heinonen, M.; Iivanainen, A.; Pessa-Morikawa, T.; Niku, M.
10.1101/2024.03.27.586787 — microbiology — Posted on 2024-03-27
878 Mutation of negative regulatory gene CEHC1 encoding an FBXO3 protein results in normoxic expression of HYDA genes in Chlamydomonas reinhardtii
Sun, X.; LaVoie, M.; Lefebvre, P.; Gallaher, S. D.; Glaesener, A. G.; Strenkert, D.; Mehta, R.; Merchant, S. S.; Silflow, C. D.
10.1101/2024.03.22.586359 — plant biology — Posted on 2024-03-27
882 Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases
Rempfer, C.; Hoernstein, S. N. W.; van Gessel, N.; Graf, A. W.; Spiegelhalder, R. P.; Bertolini, A.; Bohlender, L. L.; Parsons, J.; Decker, E. L.; Reski, R.
10.1101/2024.03.26.586753 — plant biology — Posted on 2024-03-27
883 Demographic and genetic impacts of powdery mildew in a young oak cohort
Barres, B.; Dutech, C.; Saint-Jean, G.; Bodenes, C.; Burban, C.; Fievet, V.; Lepoittevin, C.; Garnier-Gere, P.; Desprez-Loustau, M.-L.
10.1101/2023.06.22.546164 — plant biology — Posted on 2024-03-27
885 Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy
Wang, Z.; Zhao, R.; Wagenaar, D. A.; Kang, W.; Lee, C.; Schmidt, W.; Pammar, A.; Zhu, E.; Wong, G. C. L.; Liang, R.; Hsiai, T.; Gao, L.
10.1101/2024.03.23.586416 — bioengineering — Posted on 2024-03-27
886 STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy
Sheehy, T. L.; Kwiatkowski, A. J.; Arora, K.; Kimmel, B. R.; Schulman, J. A.; Gibson-Corley, K.; Wilson, J. T.
10.1101/2024.03.23.585817 — bioengineering — Posted on 2024-03-27
887 Elucidating the sustainability of 700 years of Inuvialuit beluga whale hunting in the Mackenzie River Delta, Northwest Territories, Canada
Skovrind, M.; Louis, M.; Ferguson, S.; Glazov, D. M.; Litovka, D. I.; Loseto, L. L.; Meschersky, I. G.; MIller, M. M.; Postma, L. D.; Rozhnov, V. V.; Scott, M.; Westbury, M. V.; Szpak, P.; Friesen, T. M.; Lorenzen, E. D.
10.1101/2024.03.22.586343 — genomics — Posted on 2024-03-27
888 Single-cell epigenomic dysregulation of Systemic Sclerosis fibroblasts via CREB1/EGR1 axis in self-assembled human skin equivalents
Abel, T. R.; Kosarek, N. N.; Parvizi, R.; Jarnagin, H. C.; Torres, G. M.; Bhandari, R.; Huang, M.; Toledo, D.; Smith, A.; Popovich, D.; Mariani, M. P.; Yang, H.; Wood, T. A.; Garlick, J.; Pioli, P. A.; Whitfield, M. L.
10.1101/2024.03.22.586316 — genomics — Posted on 2024-03-27
889 Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain
Shepherdson, J. L.; Granas, D. M.; Li, J.; Shariff, Z.; Plassmeyer, S. P.; Holehouse, A. S.; White, M. A.; Cohen, B. A.
10.1101/2024.03.21.585809 — genomics — Posted on 2024-03-27
890 A basic framework governing splice-site choice in eukaryotes
Dent, C. I.; Prodic, S.; Balakrishnan, A.; Georges, J.; Chhabra, A.; Mukherjee, S.; Coutts, J. P.; Gitonobel, M.; Sarwade, R. D.; Rosenbluh, J.; D'Amato, M.; Das, P. P.; Guo, Y.; Fournier-Level, A.; Burke, R.; Sureshkumar, S.; Powell, D.; Balasubramanian, S.
10.1101/2024.03.21.586179 — genetics — Posted on 2024-03-27
894 TreeCompR: Tree competition indices for inventory data and 3D point clouds
Rieder, J. S.; Link, R. M.; Köthe, K.; Seidel, D.; Ullmann, T.; Zmegac, A.; Zang, C.; Schuldt, B.
10.1101/2024.03.23.586379 — ecology — Posted on 2024-03-27
895 Sediment-associated processes drive spatial variation in ecosystem respiration in the Yakima River basin
Kaufman, M.; Garayburu-Caruso, V.; Forbes, B.; Lin, X.; Hall, R.; Fulton, S.; Renteria, L.; Fang, Y.; Son, K.; Stegen, J. C.
10.1101/2024.03.22.586339 — ecology — Posted on 2024-03-27
899 Unusual lineage plasticity revealed by YY1 knockout in pro-B cells
Banerjee, S.; Sanyal, S.; Hodawadekar, S.; Naiyer, S.; Bano, N.; Banerjee, A.; Rhoades, J.; Dong, D.; Allman, D.; Atchison, M. L.
10.1101/2024.03.22.586298 — developmental biology — Posted on 2024-03-27
900 The Outer Kinetochore Proteins KNL-1 and Ndc80 complex are Required to Pattern the Central Nervous System
Cheerambathur, D. K.; Ouzounidis, V. R.; Green, M.; Crellin, H.; de Ceuninck, C.; Gebhardt, C.; Finlayson, C.; Prevo, B.
10.1101/2024.03.27.586904 — cell biology — Posted on 2024-03-27
902 A Hollow TFG Condensate Spatially Compartmentalizes the Early Secretory Pathway
Wegeng, W. R.; Bogus, S. M.; Ruiz, M.; Chavez, S. R.; Noori, K. S. M.; Niesman, I. R.; Ernst, A. M.
10.1101/2024.03.26.586876 — cell biology — Posted on 2024-03-27
905 The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator That is Sufficient for Growth
Edman, S.; Jones, R. G.; Jannig, P. R.; Fernandez-Gonzalo, R.; Norrbom, J.; Thomas, N. T.; Khadgi, S.; Koopmans, P. J.; Morena, F.; Peterson, C. S.; Scott, L. N.; Greene, N. P.; Figueiredo, V. C.; Fry, C. S.; Zhengye, L.; Lanner, J. T.; Wen, Y.; Alkner, B.; Murach, K. A.; von Walden, F.
10.1101/2024.03.26.586857 — cell biology — Posted on 2024-03-27
906 The Evolutionary Origins and Ancestral Features of Septins
Delic, S.; Shuman, B.; Lee, S.; Bahmanyar, S.; Momany, M.; Onishi, M.
10.1101/2024.03.25.586683 — cell biology — Posted on 2024-03-27
907 Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2
Harper, J. W.; Kraus, F.; He, Y.; Swarup, S.; Overmyer, K. A.; Brenner, J.; Capitanio, C.; Bieber, A.; Jen, A.; Nightingale, N. M.; Anderson, B. J.; Lee, C.; Paulo, J. A.; Smith, I. R.; Plitzko, J. M.; Schulman, B. A.; Wilfling, F.; Coon, J. J.
10.1101/2024.03.26.586828 — cell biology — Posted on 2024-03-27
908 Morphoregulatory ADD3 underlies glioblastoma growth and formation of tumor-tumor connections
Barelli, C.; Kaluthantrige Don, F.; Iannuzzi, R. M.; Bertani, I.; Osei, I.; Sorrentino, S.; Villa, G.; Sokolova, V.; Iorio, F.; Kalebic, N.
10.1101/2024.03.26.586725 — cell biology — Posted on 2024-03-27
912 Glutaminase deficiency in rod photoreceptors disrupts nonessential amino acid levels to activate the integrated stress response and induce rapid degeneration
Goswami, M. T.; Weh, E.; Subramanya, S.; Weh, K. M.; Durumutla, H. B.; Hager, H.; Miller, N.; Chaudhury, S.; Andren, A.; Sajjakulnukit, P.; Besirli, C. G.; Lyssiotis, C. A.; Wubben, T. J.
10.1101/2024.03.26.582525 — cell biology — Posted on 2024-03-27
913 Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton
Bourne, L. E.; Jayash, S. N.; Michels, L. V.; Hopkinson, M.; Guppy, F. M.; Clarkin, C. E.; Gard, P.; Brissett, N.; Staines, K. A.
10.1101/2024.03.27.586945 — cell biology — Posted on 2024-03-27
916 BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress
Sepulveda, C.; Milani, M.; Morales, V.; Tamburini, G.; Montes, N.; Hetz, C.
10.1101/2024.03.26.586784 — cell biology — Posted on 2024-03-27
919 A molecular switch orchestrates the nuclear export of human messenger RNA
Hohmann, U.; Graf, M.; Schellhaas, U.; Pacheco-Fiallos, B.; Fin, L.; Riabov-Bassat, D.; Pühringer, T.; Szalay, M.-F.; Tirian, L.; Handler, D.; Brennecke, J.; Plaschka, C.
10.1101/2024.03.24.586400 — molecular biology — Posted on 2024-03-27
932 Effect of temperature on circadian clock functioning of trees in the context of global warming
Estravis-Barcala, M.; Gaischuk, S.; Gonzalez-Polo, M.; Martinez-Meier, A.; Gutierrez, R. A.; Yanovsky, M. J.; Bellora, N.; Arana, M. V.
10.1101/2024.03.22.586279 — plant biology — Posted on 2024-03-27
937 Telomere Length in Plants Estimated with Long Read Sequencing
Colt, K.; Petrus, S.; Abramson, B. W.; Mamerto, A.; Hartwick, N. T.; Michael, T. P.
10.1101/2024.03.27.586973 — plant biology — Posted on 2024-03-27
938 Diurnal regulation of SOS Pathway and Sodium Excretion Underlying Salinity Tolerance of Vigna marina
Noda, Y.; Wang, F.; Chankaew, S.; Ariga, H.; Muto, C.; Iki, Y.; Ohashi, H.; Takahashi, Y.; Sakai, H.; Iseki, K.; Ogiso-Tanaka, E.; Suzui, N.; Yin, Y.-G.; Miyoshi, Y.; Enomoto, K.; Kawachi, N.; Somta, P.; Furukawa, J.; Tomooka, N.; Naito, K.
10.1101/2024.03.26.586888 — plant biology — Posted on 2024-03-27
940 TFIIS is required for reproductive development and thermal adaptation in barley
Ahmad, I.; Andras, K.; Verma, R.; Szadeczky-Kardoss, I.; Szaker, H. M.; Pettko-Szandtner, A.; Silhavy, D.; Havelda, Z.; Csorba, T.
10.1101/2024.03.26.586761 — plant biology — Posted on 2024-03-27
941 An efficient inducible model for the control of gene expression in renin cells
Medrano, S.; Yamaguchi, M.; Yamaguchi, H.; Almeida, L.; Sigmund, C.; Sequeira-Lopez, M. L. S.; Gomez, A.
10.1101/2024.03.26.585202 — physiology — Posted on 2024-03-27
943 Broad therapeutic benefit of myosin inhibition in hypertrophic cardiomyopathy
Sen Martin, L.; Fernandez Trasancos, A.; Lopez Unzu, M. A.; Pathak, D.; Ferrarini, A.; Labrador Cantarero, V.; Sanchez Ortiz, D.; Pricolo, M. R.; Vicente, N.; Velazquez Carreras, D.; Sanchez Garcia, L.; Nicolas Avila, J. A.; Sanchez Diaz, M.; Schlossarek, S.; Cusso, L.; Desco, M.; Villalba Orero, M.; Guzman Martinez, G.; Calvo, E.; Barriales Villa, R.; Vazquez, J.; Sanchez Cabo, F.; Hidalgo, A.; Carrier, L.; Spudich, J.; Ruppel, K. M.; Alegre Cebollada, J.
10.1101/2024.03.22.584986 — physiology — Posted on 2024-03-27
945 Screening and characterization of 133 physiologically-relevant environmental chemicals for reproductive toxicity
Ulaganathan, G.; Jiang, H.; Canio, N.; Oke, A.; Armstrong, S. S.; Abrahamsson, D.; Varshavsky, J. R.; Lam, J.; Cooper, C.; Robinson, J. F.; Fung, J.; Woodruff, T. J.; Allard, P.
10.1101/2024.03.22.584808 — pharmacology and toxicology — Posted on 2024-03-27
948 Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma
Teisseire, M.; Sahu, U.; Parola, J.; Tsai, M.-C.; Vial, V.; Durivault, J.; Grepin, R.; Cormerais, Y.; Pages, G.; Ben-Sahra, I.; Giuliano, S.
10.1101/2024.03.22.586287 — cancer biology — Posted on 2024-03-27
949 Targeting Fatty Acid Desaturase I Inhibits Renal Cancer Growth Via ATF3-mediated ER Stress Response
Heravi, G.; Liu, Z.; Herroon, M.; Wilson, A.; Fan, Y. Y.; Jiang, Y.; Vakeesan, N.; Tao, L.; Peng, Z.; Zhang, K.; Li, J.; Chapkin, R. S.; Podgorski, I.; Liu, W.
10.1101/2024.03.23.586426 — cancer biology — Posted on 2024-03-27
950 Androgen receptor-negative prostate cancer is vulnerable to SWI/SNF-targeting degrader molecules
Thienger, P. D.; Rubin, P. D.; Yao, X.; Benjak, A.; Shah, S.; King-Yung Leung, A.; de Brot, S.; Naveed, A.; Shi, M.; Tremblay, J.; Triscott, J.; Cassanmagnano, G.; Bolis, M.; Mela, L.; Beltran, H.; Chen, Y.; Piscuoglio, S.; Yu, H.; Ng, C. K.; Yauch, R.; Rubin, M. A.
10.1101/2024.03.24.586276 — cancer biology — Posted on 2024-03-27
951 An Innovative Mitochondrial-targeted Gene Therapy for Cancer Treatment
Chen, K.; Ernst, P.; Kim, S.; Si, Y.; Varadkar, T.; Ringel, M.; Liu, X.; Zhou, L.
10.1101/2024.03.24.584499 — cancer biology — Posted on 2024-03-27
957 Self-quenched fluorophore-DNA labels for super-resolution fluorescence microscopy
Kessler, L. F.; Balakrishnan, A.; Menche, T.; Wang, D.; Li, Y.; Mantel, M.; Glogger, M.; Dietz, M. S.; Heilemann, M.
10.1101/2024.03.24.586443 — biophysics — Posted on 2024-03-27
964 Exploring Pathogenic Mutation in Allosteric Proteins: the Prediction and Beyond
Zhang, H.; Ju, Z.; Zhang, J.; Li, X.; Xiao, H.; Chen, X.; Li, Y.; Wang, X.; Wei, Y.
10.1101/2024.03.23.586438 — bioinformatics — Posted on 2024-03-27
965 OmicsFootPrint: a framework to integrate and interpret multi-omics data using circular images and deep neural networks
Tang, X.; Prodduturi, N.; Thompson, K. J.; Weinshilboum, R. M.; O'Sullivan, C. C.; Boughey, J. C.; Tizhoosh, H.; Klee, E. W.; Wang, L.; Goetz, M. P.; Suman, V.; Kalari, K. R.
10.1101/2024.03.21.586001 — bioinformatics — Posted on 2024-03-27
967 MICROMANIPULATION OF LIVE MICRODISSECTED TISSUES WITH A LOW-COST INTEGRATED ROBOTIC PLATFORM
Gottshall, N. R.; Stepanov, I.; Ahmadianyazdi, A.; Sinha, D.; Lockhart, E.; Nguyen, T. N.; Hassan, S.; Horowitz, L.; Yeung, R.; Gujral, T. S.; Folch, A.
10.1101/2024.03.21.586169 — bioengineering — Posted on 2024-03-27
969 Engineered Flt3L Drives Tolerogenic State to Attenuate Anti-drug Antibody Responses
Alpar, A. T.; Wallace, R. P.; Refvik, K. C.; Gomes, S.; Solanki, A.; Gray, L. T.; Slezak, A. J.; Lauterbach, A. L.; Hesser, L. A.; Cao, S.; Medellin, J. E. G.; Robinson, L. G.; Hubbell, J. A.
10.1101/2024.03.21.586168 — bioengineering — Posted on 2024-03-27
970 A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation
Nguyen, V. C. B.; Özden, C.; Dong, K.; Torres-Ocampo, A. P.; Dziedzic, N.; Flaherty, D.; Huang, J.; Sankura, S.; Abromson, N. L.; Tomchick, D. R.; Chen, J.; Garman, S. C.; Stratton, M.
10.1101/2024.03.24.586494 — biochemistry — Posted on 2024-03-27
971 Long Amplicon Nanopore Sequencing for Dual-Typing RdRp and VP1 Genes of Norovirus Genogroups I and II in Wastewater
Scott, G.; Ryder, D.; Buckley, M.; Hill, R.; Treagus, S.; Stapleton, T.; Walker, D. I.; Lowther, J.; Batista, F. M.
10.1101/2024.03.27.584784 — molecular biology — Posted on 2024-03-27
975 Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation
Caetano-Silva, M. E.; Shrestha, A.; Duff, A. F.; Kontic, D.; Brewster, P. C.; Kasperek, M. C.; Lin, C. H.; Wainwright, D. A.; Saavedra, D. H.; Woods, J. A.; Bailey, M. T.; Buford, T. W.; Allen, J. M.
10.1101/2024.03.22.586320 — immunology — Posted on 2024-03-27
976 Single cell resolution analysis of multi-tissue derived human iNKT cells reveals novel transcriptional paradigms
Jayasinghe, R. G.; Hollingsworth, D.; Boonchalermvichian, C.; Gupta, B.; Yan, H.; Baker, J.; Dejene, B.; Weinberg, K. I.; Negrin, R. S.; Mavers, M.
10.1101/2024.03.22.583992 — immunology — Posted on 2024-03-27
977 Retinal microglia exacerbate uveitis by functioning as local antigen-presenting cells
Shirahama, S.; Okunuki, Y.; Lee, M. Y.; Karg, M. M.; Refaian, N.; Krasniqi, D.; Connor, K. M.; Gregory-Ksander, M. S.; Ksander, B. R.
10.1101/2024.03.23.586440 — immunology — Posted on 2024-03-27
978 Investigating Cryopreserved PBMC Functionality in an Antigen-Induced Model of Sarcoidosis Granuloma Formation
Seman, S. G.; Bicer, S.; Julian, M. W.; Kramer, P. J.; Mitchell, J. R.; Crouser, E. D.; LOCKE, L. W.
10.1101/2024.03.23.586344 — immunology — Posted on 2024-03-27
979 Role of Posterior Medial Thalamus in the Modulation of Striatal Circuitry and Choice Behavior
Yonk, A. J.; Linares-Garcia, I.; Pasternak, L.; Juliani, S. E.; Gradwell, M. A.; George, A. J.; Margolis, D. J.
10.1101/2024.03.21.586152 — neuroscience — Posted on 2024-03-27
982 Enhancing tonic arousal improves voluntary but not involuntary attention in humans
Grandjean, A.; Mathieu, A.; Chen, S.; Widmann, A.; Wetzel, N.; Bidet-Caulet, A.
10.1101/2024.03.22.586259 — neuroscience — Posted on 2024-03-27
984 Implantable Bioelectronics for Real-time in vivo Recordings of Enteric Neural Activity
Boys, A. J.; Güemes, A. J.; Gupta, R. A.; Uhlig, F. H.; Hyland, N. P.; Bulmer, D. C.; Malliaras, G. G.; Owens, R. M.
10.1101/2024.03.22.586292 — neuroscience — Posted on 2024-03-27
985 Multidimensional analysis of cortical interneuron synaptic features reveals underlying synaptic heterogeneity
Dummer, P.; Lee, D.; Hossain, S.; Wang, R.; Evard, A.; Schneider-Mizell, C. M.; Menon, V.; Au, E.
10.1101/2024.03.22.586340 — neuroscience — Posted on 2024-03-27
987 Modeling responses of macaque and human retinal ganglion cells to natural images using a convolutional neural network
Gogliettino, A. R.; Cooler, S.; Vilkhu, R. S.; Brackbill, N. J.; Rhoades, C.; Wu, E. G.; Kling, A.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2024.03.22.586353 — neuroscience — Posted on 2024-03-27
989 A functional overlap between evidence accumulation, confidence, and changes of mind in the pre-supplementary motor area and insula
Goueytes, D.; Stockart, F.; Robin, A.; Gyger, L.; Rouy, M.; Hoffmann, D.; Minotti, L.; Kahane, P.; Pereira, M.; Faivre, N.
10.1101/2024.03.23.586414 — neuroscience — Posted on 2024-03-27
992 Microdissected tumor cuboids: a microscale cancer model that retains a complex tumor microenvironment
Horowitz, L. F.; Rodriguez-Mias, R. A.; Zhu, S.; Gottshall, N. R.; Stepanov, I.; Stiles, C.; Yeung, M.; Nguyen, T. N.; Lockhart, E. J.; Yeung, R. S.; Villen, J.; Gujral, T. S.; Folch, A.
10.1101/2024.03.22.586189 — cancer biology — Posted on 2024-03-27
1001 Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection.
Abdullah, L.; Emiliani, F. E.; Vaidya, C. M.; Stuart, H.; Kolling, F. W.; Ackerman, M. E.; Song, L.; McKenna, A.; Huang, Y. H.
10.1101/2024.03.21.586160 — immunology — Posted on 2024-03-27
1003 Link between respiratory pauses and vigilance states in freely moving mice
Casali, G.; Miermon, C.; Terral, G.; Ravassard, P.; Dolique, T.; Lesburgueres, E.; Jarriault, D.; Gambino, F.; Chenouard, N.; Roux, L.
10.1101/2024.03.27.586921 — neuroscience — Posted on 2024-03-27
1007 The Genomes of Nematode-Trapping Fungi Provide Insights into the Origin and Diversification of Fungal Carnivorism
Fan, Y.; Du, M.; Zhang, W.; Deng, W.; Yang, E.; Wang, S.; Yan, L.; Zhang, L.; Kang, S.; Steenwyk, J. L.; An, Z.; Liu, X.; Xiang, M.
10.1101/2024.03.21.586190 — evolutionary biology — Posted on 2024-03-27
1008 Whole-genome resequencing revealed the Origin and Domestication of Chinese Domestic Rabbits
Xie, K.; Song, Z.; Wang, Y.; Di, Y.; Li, W.; Wang, Y.; Yang, A.; Qiao, X.; Wang, B.; Li, M.; Xie, X.; Xie, X.; Liu, L.; Ning, C.; Tang, H.; Li, X.; Wu, X.; Wang, D.; Fan, X.
10.1101/2024.03.26.586758 — evolutionary biology — Posted on 2024-03-27
1011 The Sociodemographic and Lifestyle Correlates of Epigenetic Aging in a Nationally Representative U.S. Study of Younger Adults
Harris, K. M.; Levitt, B. E.; Gaydosh, L.; Martin, C.; Meyer, J. M.; Mishra, A. A.; Kelly, A. L.; Aiello, A. E.
10.1101/2024.03.21.585983 — genomics — Posted on 2024-03-27
1012 Mapping the distribution of seagrass meadows from space with deep convolutional neural networks
Gimenez-Romero, A.; Ferchichi, D.; Moreno-Spiegelberg, P.; Sintes, T.; Matias, M. A.
10.1101/2024.03.21.586047 — ecology — Posted on 2024-03-27
1016 A Systematic Assessment of Robustness in CNS Safety Pharmacology
Reiber, M.; Stirling, H.; Ahuis, T. P.; Arias, W.; Aulehner, K.; Dressler, U.; Kas, M. J. H.; Kela, J.; Kerker, K.; Kuosmanen, T.; Lorenz, H.; Pennington, A. T.; von Ruden, E.-L.; Schauerte, H.; Seiffert, I.; Talbot, S. R.; Torturo, C.; Virtanen, S.; Waldron, A.-M.; Ramboz, S.; Potschka, H.
10.1101/2024.03.21.586096 — neuroscience — Posted on 2024-03-27
1018 The technical-reasoning network is recruited when people observe others make or teach how to make tools: An fMRI study
Bluet, A.; Reynaud, E.; Federico, G.; Bryche, C.; Lesourd, M.; Fournel, A.; Lamberton, F.; Ibarrola, D.; Rossetti, Y.; Osiurak, F.
10.1101/2024.03.21.586121 — neuroscience — Posted on 2024-03-27
1022 Edinger-Westphal ghrelin receptor signalling regulates binge alcohol consumption in a sex specific manner
Pearl, A.; Pinares-Garcia, P.; Shesham, A.; Maddern, X.; Anversa, R.; Brown, R.; Reed, F. M.; Giardino, W.; Lawrence, A. J.; Walker, L.
10.1101/2024.03.23.586439 — neuroscience — Posted on 2024-03-27
1023 Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction
Bayer, H.; Hassell, J. E.; Oleksiak, C. R.; Garcia, G. M.; Vaughan, H.; Juliano, V. A. L.; Maren, S.
10.1101/2024.03.23.586410 — neuroscience — Posted on 2024-03-27
1024 Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis
Yoo, K.; Jo, Y.-W.; Yoo, T.; Hann, S.-H.; Park, I.; Kim, Y.-E.; Kim, Y. L.; Rhee, J.; Song, I.-W.; Kim, J.-H.; Baek, D.; Kong, Y.-Y.
10.1101/2024.03.25.586563 — neuroscience — Posted on 2024-03-27
1025 T cell receptor-centric perspective to multimodal single-cell data analysis.
Mullan, K. A.; Ha, M.; Valkiers, S.; de Vrij, N.; Ogunjimi, B.; Laukens, K.; Meysman, P.
10.1101/2023.09.27.559702 — bioinformatics — Posted on 2024-03-27
1029 Puberty Blocker and Aging Impact on Testicular Cell States and Function
Murugesh, V.; Ritting, M.; Salem, S. M.; Aalam, S. M. M.; Garcia, J.; Chattha, A. J.; Zhao, Y.; Knapp, D. J.; Kalthur, G.; Granberg, C. F.; Kannan, N.
10.1101/2024.03.23.586441 — developmental biology — Posted on 2024-03-27
1030 Tonically active GABAergic neurons in the dorsal periaqueductal gray control the initiation and execution of instinctive escape
Stempel, A. V.; Evans, D. A.; Pavon Arocas, O.; Claudi, F.; Lenzi, S. C.; Kutsarova, E.; Margrie, T. W.; Branco, T.
10.1101/2023.11.03.565561 — neuroscience — Posted on 2024-03-27
1031 Parameter variability makes a major contribution to uncertainty of crop phenology simulations
Wallach, D.; Palosuo, T.; Mielenz, H.; Buis, S.; Thorburn, P.; Asseng, S.; Dumont, B.; Ferrise, R.; Gayler, S.; Ghahramani, A.; Harrison, M. T.; Hochman, Z.; Hoogenboom, G.; Huang, M.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Launay, M.; Lewan, E.; Liu, K.; Luo, Q.; Mequanint, F.; Nendel, C.; Padovan, G.; Olesen, J. E.; Pullens, J. W. M.; Qian, B.; Seserman, D.-M.; Shelia, V.; Souissi, A.; Specka, X.; Wang, J.; Weber, T. K. D.; Weihermuller, L.; Seidel, S.
10.1101/2023.02.03.526931 — plant biology — Posted on 2024-03-27
1034 Liquid phase electron microscopy of bacterial ultrastructure
Caffrey, B. J.; Pedrazo-Tardajos, A.; Liberti, E.; Gaunt, B.; Kim, J. S.; Kirkland, A. I.
10.1101/2024.02.27.580996 — microbiology — Posted on 2024-03-27
1035 Stimulus duration encoding occurs early in the moth olfactory pathway
Barta, T.; Montsempes, C.; Demondion, E.; Chatterjee, A.; Kostal, L.; Lucas, P.
10.1101/2022.07.21.501055 — neuroscience — Posted on 2024-03-27
1037 Acquisition of Auditory Discrimination Mediated by Different Processes through Two Distinct Circuits Linked to the Lateral Striatum
Setogawa, S.; Okauchi, T.; Hu, D.; Wada, Y.; Hikishima, K.; Onoe, H.; Nishizawa, K.; Sakayori, N.; Miyawaki, H.; Kitanishi, T.; Mizuseki, K.; Cui, Y.; Kobayashi, K.
10.1101/2023.10.19.563198 — animal behavior and cognition — Posted on 2024-03-27
1038 SegmentNT: annotating the genome at single-nucleotide resolution with DNA foundation models
de Almeida, B. P.; Dalla-Torre, H.; Richard, G.; Blum, C.; Hexemer, L.; Gelard, M.; Mendoza-Revilla, J.; Pandey, P.; Laurent, S.; Lopez, M.; Laterre, A.; Lang, M.; Sahin, U.; Beguir, K.; Pierrot, T.
10.1101/2024.03.14.584712 — genomics — Posted on 2024-03-27
1040 A diversity of diversities: do complex environmental effects underpin associations between below- and aboveground taxa?
Seaton, F. M.; George, P. B.; Alison, J.; Jones, D. L.; Creer, S.; Smart, S. M.; Emmett, B.; Robinson, D. A.
10.1101/2023.06.07.544003 — ecology — Posted on 2024-03-27
1041 Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease
Chen, O. Y.; Vu, D. T.; Diaz, C. S.; Bodelet, J. S.; Phan, H.; Allali, G.; Nguyen, V.-D.; Cao, H.; He, X.; Muller, Y.; Zhi, B.; Shou, H.; Zhang, H.; He, W.; Wang, X.; Munafo, M.; Trung, N. L.; Nagels, G.; Ryvlin, P.; Pantaleo, G.
10.1101/2024.03.11.584383 — neuroscience — Posted on 2024-03-27
1042 The cellular representation of temperature across the somatosensory thalamus
Leva, T.; Whitmire, C.; Sauve, I.; Bokiniec, P.; Memler, C.; Horn, B.; Vestergaard, M.; Carta, M.; Poulet, J. F. A.
10.1101/2024.02.13.580167 — neuroscience — Posted on 2024-03-27
1043 Mixed clonal-aggregative multicellularity entrained by extreme salinity fluctuations in a close relative of animals
Ros-Rocher, N.; Reyes-Rivera, J.; Foroughijabbari, Y.; Combredet, C.; Larson, B. T.; Coyle, M. C.; Houtepen, E. A. T.; Vermeij, M. J. A.; King, N.; Brunet, T.
10.1101/2024.03.25.586565 — evolutionary biology — Posted on 2024-03-27
1047 Toxin-glycolipid interactions measured by imaging surface plasmon resonance on artificial membranes predicts diffusion behavior and lipid dependence of binding to cells
Lehnert, S.; Yildiz, U. H.; Haustein, N.; Li, E.; Matysik, A.; Oglecka, K.; Rashid, R.; Boschke, E.; Liedberg, B.; Wohland, T.; Kraut, R.
10.1101/2024.03.22.586282 — cell biology — Posted on 2024-03-27
1050 Establishing Primary and Stable Cell Lines from Frozen Wing Biopsies for Cellular, Physiological, and Genetic Studies in Bats
Zhao, C.; Camacho, J.; Rohner, N.; Deng, F.; Morales-Sosa, P.; Bernal-Rivera, A.; Wang, Y.; Tsuchiya, D.; Javier, J.
10.1101/2024.03.22.586286 — cell biology — Posted on 2024-03-27
1051 Prevalence study of cellular capsid-specific immune responses to AAV2, 4, 5, 8, 9 and rh10 in healthy donors
Xicluna, R.; Avenel, A.; Vandamme, C.; Devaux, M.; Jaulin, N.; Couzinie, C.; Le Duff, J.; Charrier, A.; Guilbaud, M.; Adjali, O.; Gernoux, G.
10.1101/2023.12.20.570598 — immunology — Posted on 2024-03-27
1053 Human stem cell derived neurons and astrocytes to detect novel auto-reactive IgG signature in immune-mediated neurological diseases
Mathias, A.; Perriot, S.; Jones, S.; Canales, M.; Bernard-Valnet, R.; Gimenez, M.; Torcida, N.; Oberholster, L.; Hottinger, A. F.; Zekeridou, A.; Theaudin, M.; Pot, C.; Du Pasquier, R.
10.1101/2024.02.26.582006 — neuroscience — Posted on 2024-03-27
1054 Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers
Lee, G.; Wong, C.; Cho, A.; West, J. J.; Crawford, A. J.; Russo, G. C.; Si, B. R.; Kim, J.; Hoffner, L.; Jang, C.; Jung, M.; Leone, R. D.; Konstantopoulos, K.; Ewald, A. J.; Wirtz, D.; Jeong, S.
10.1101/2023.05.24.541452 — cancer biology — Posted on 2024-03-26
1055 An experimental study of free flight kinematics in a miniature parasitoid wasp Trichogramma telengai
Lapina, N. A.; Farisenkov, S. E.; Shcherbakov, E. O.; Kolomenskiy, D.; Polilov, A. A.
10.1101/2024.03.21.586056 — biophysics — Posted on 2024-03-26
1058 Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking and kinase inhibition
Narayanan, D.; Larsen, A. S. G.; Gauger, S. J.; Adafia, R.; Hammershoi, R. B.; Hamborg, L.; Bruus-Jensen, J.; Griem-Krey, N.; Gee, C. L.; Frolund, B.; Stratton, M. M.; Kuriyan, J.; Kastrup, J. S.; Langkilde, A. E.; Wellendorph, P.; Solbak, S. M. O.
10.1101/2024.03.26.586665 — biophysics — Posted on 2024-03-27
1060 Prediction of plant complex traits via integration of multi-omics data
Wang, P.; Lehti-Shiu, M. D.; Lotreck, S.; Segura Aba, K.; Krysan, P. J.; Shiu, S.-H.
10.1101/2023.11.14.566971 — bioinformatics — Posted on 2024-03-26
1061 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening
Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.
10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-27
1063 In silico mechanics of stem cells intramyocardially transplanted with a biomaterial injectate for treatment of myocardial infarction
Motchon, Y. D.; Sack, K. L.; Sirry, M. S.; Nchejane, N. J.; Abdalrahman, T.; Nagawa, J.; Kruger, M.; Pauwels, E.; Van Loo, D.; De Muynck, A.; Van Hoorebeke, L.; Davies, N. H.; Franz, T.
10.1101/2023.05.10.540185 — bioengineering — Posted on 2024-03-27
1065 CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge
Whitelaw, J. A.; Lilla, S.; Nikolaou, S.; Tweedy, L.; Fort, L.; Paul, N. R.; Zanivan, S.; Gadegaard, N.; Insall, R. H.; Machesky, L. M.
10.1101/2024.03.26.586838 — cell biology — Posted on 2024-03-27
1067 A cell-free workflow for detecting and characterizing RiPP recognition element-precursor peptide interactions
Wong, D. A.; Cabezas, M. D.; Daniel-Ivad, M.; Prasanna, D. V.; Fernandez, R.; Nicol, R.; Balskus, E. P.; Karim, A. S.; Jewett, M. C.
10.1101/2024.03.25.586624 — synthetic biology — Posted on 2024-03-26
1068 Hybrid Sequencing Facilitates Robust De Novo Plasmid Assembly
Hernandez, S. I.; Berezin, C.-T.; Miller, K. M.; Peccoud, S. J.; Peccoud, J.
10.1101/2024.03.25.586694 — synthetic biology — Posted on 2024-03-26
1069 Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy
Lichauco, C.; Foss, E. J.; Gatbonton-Schwager, T.; Athow, N. F.; Lofts, B.; Acob, R.; Taylor, E.; Lao, U.; Miles, s.; Bedalov, A.
10.1101/2024.03.21.586113 — genetics — Posted on 2024-03-26
1073 Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors
Johnston, A. C.; Alicea, G. M.; Lee, C. C.; Patel, P. V.; Hanna, E. A.; Vaz, E.; Forjaz, A.; Wan, Z.; Nair, P. R.; Lim, Y.; Chen, T.; Du, W.; Kim, D.; Nichakawade, T. D.; Rebecca, V. W.; Bonifant, C. L.; Fan, R.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.
10.1101/2023.12.13.571595 — immunology — Posted on 2024-03-26
1074 LC3-associated phagocytosis is impaired in monocyte-derived macrophages from systemic sclerosis patients
Frenger, Q.; Lucas, J.; Petitdemange, A.; Path, L.; Baldeck, N.; Depauw, S.; Giorgiutti, S.; Merlin, H.; Gong, Y.; Meyer, A.; Herber, M.; Jacquel, L.; Mertz, P.; Felten, R.; Chatelus, E.; Dieudonne, Y.; Guffroy, A.; Arnaud, L.; Poindron, V.; Gottenberg, J.-E.; Sibilia, J.; Korganow, A.-S.; Martin, T.; Gros, F.
10.1101/2024.03.21.586112 — immunology — Posted on 2024-03-26
1075 Developmental pyrethroid exposure disrupts folate metabolism in mouse brain
Curtis, M. A.; Saferin, N.; Nguyen, J. H.; Imami, A. S.; Neifer, K. L.; Miller, G. W.; Burkett, J. P.
10.1101/2023.10.13.562226 — neuroscience — Posted on 2024-03-26
1076 Neural manifolds in V1 change with top-down signals from V4 targeting the foveal region
Morales-Gregorio, A.; Kurth, A. C.; Ito, J.; Kleinjohann, A.; Barthelemy, F. V.; Brochier, T.; Grün, S.; van Albada, S. J.
10.1101/2023.06.14.544966 — neuroscience — Posted on 2024-03-26
1077 Investigation of the Fasciola Cinereum, Absent in BTBR mice, and Comparison with the Hippocampal Area CA2
Lee, S. H.; Cooke, M. E.; Duan, K. Z.; Williams Avram, S.; Song, J.; Elkahloun, A. G.; McGrady, G.; NISC Comparative Sequencing Program, ; Howley, A.; Samal, B.; Young, W. S.
10.1101/2024.03.21.586108 — neuroscience — Posted on 2024-03-26
1081 ComPRePS: An Automated Cloud-based Image Analysis tool to democratize AI in Digital Pathology
Mimar, S.; Paul, A. S.; Lucarelli, N.; Boarder, S.; Naglah, A.; Barisoni, L.; Hodgin, J.; Rosenberg, A.; Clapp, W.; Sarder, P.
10.1101/2024.03.21.586102 — pathology — Posted on 2024-03-26
1090 Expansion of pneumococcal serotype 23F and 14 lineages with genotypic changes in capsule polysaccharide locus and virulence gene profiles post introduction of pneumococcal conjugate vaccine in Blantyre, Malawi
Cave, R.; Kalizang'oma, A.; Chaguza, C.; Mwalukomo, T. S.; Kamng'ona, A.; Brown, C.; Msefula, J.; Bonomali, F.; Nyirenda, R.; Swarthout, T. D.; Kwambana-Adams, B.; French, N.; Heyderman, R. S.
10.1101/2024.03.25.586540 — microbiology — Posted on 2024-03-26
1091 The expression of integron arrays is shaped by the translation rate of cassettes
Carvalho, A.; Hipolito, A.; Trigo da Roza, F.; Garcia-Pastor, L.; Vergara, E.; Buendia, A.; Garcia-Seco, T.; Escudero, J. A.
10.1101/2024.03.26.586746 — microbiology — Posted on 2024-03-26
1093 Global stress response in Pseudomonas aeruginosa upon malonate utilization
Bisht, K.; Elmassry, M. M.; al Mahmud, H.; Bhattacharjee, S.; Deonarine, A.; Black, C.; San Francisco, M.; Hamood, A. N.; Wakeman, C. A.
10.1101/2024.03.26.586813 — microbiology — Posted on 2024-03-26
1094 Isolation and characterization of a phage collection against Pseudomonas putida
Brauer, A.; Rosendahl, S.; Kangsep, A.; Lewanczyk, A. C.; Rikberg, R.; Horak, R.; Tamman, H.
10.1101/2024.03.26.586772 — microbiology — Posted on 2024-03-26
1095 Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens
Tse, M. W.; Zhu, M.; Peters, B.; Hamami, E.; Chen, J.; Davis, K. P.; Nitz, S.; Weller, J.; Warrier, T.; Hunt, D. K.; Morales, Y.; Kawate, T.; Gaulin, J. L.; Come, J. H.; Hernandez-Bird, J.; Huo, W.; Neisewander, I.; Kiessling, L. L.; Hung, D. T.; Mecsas, J.; Aldridge, B. B.; Isberg, R. R.; Blainey, P. C.
10.1101/2024.03.26.586803 — microbiology — Posted on 2024-03-26
1097 ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.
Schmid, S.; Russell, Z. R.; Yamashita, A. S.; West, M. E.; Parrish, A. G.; Walker, J.; Rudoy, D.; Yan, J. Z.; Quist, D. C.; Gessesse, B. N.; Alvinez, N.; Cimino, P. J.; Kumasaka, D. K.; Parchment, R. E.; Holland, E. C.; Szulzewsky, F.
10.1101/2024.03.13.584849 — cancer biology — Posted on 2024-03-26
1098 Assembly of mTORC3 involves binding of ETV7 to two separate sequences in the mTOR kinase domain.
Zhan, J.; Harwood, F. C.; Have, S. T.; Lamond, A. I.; Halder, P.; Kriwacki, R.; Grosveld, G. C.; Phillips, A.
10.1101/2024.03.19.583970 — cancer biology — Posted on 2024-03-26
1101 Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin
Zhang, N.; Wu, J.; Hossain, F.; Peng, H.; Li, H.; Gibson, C.; Chen, M.; Zhang, H.; Gao, S.; Zheng, X.; Wang, Y.; Zhu, J.; Wang, J. J.; Maze, I.; Zheng, Q.
10.1101/2024.03.20.586010 — biochemistry — Posted on 2024-03-26
1103 Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms
Bendzunas, G.; Byrne, D. P.; Shrestha, S.; Daly, L. A.; Oswald, S. O.; Katiyar, S.; Venkat, A.; Yeung, W.; Eyers, C. E.; Eyers, P. A.; Kannan, N.
10.1101/2023.10.05.561145 — biochemistry — Posted on 2024-03-26
1106 Natural and age-related variation in circulating human hematopoietic stem cells
Furer, N.; Rappoport, N.; Lifshitz, A.; bercovich, A.; Ben-Kiki, O.; Danin, A.; Kedmi, M.; Shipony, Z.; Lipson, D.; Meiri, E.; Yanai, G.; Shapira, S.; Arber, N.; Berdichevsky, S.; Tavor, S.; Tyner, J.; Joshi, S. K.; Landau, D.; Ganesan, S.; Dusaj, N.; Chamely, P.; Kaushansky, N.; Chapal Ilani, N.; Shamir, R.; Tanay, A.; Shlush, L.
10.1101/2023.11.30.569167 — molecular biology — Posted on 2024-03-26
1108 Comparative pathogenesis of two lineages of Powassan virus reveals distinct clinical outcome, neuropathology, and inflammation.
Reynolds, E.; Hart, C.; Nelson, J.; Marzullo, B.; Esterly, A.; Paine, D.; Crooker, J.; Massa, P.; Thangamani, S.
10.1101/2023.08.01.551588 — microbiology — Posted on 2024-03-26
1110 A dynamin-like protein in the human malaria parasite plays an essential role in mitochondrial homeostasis and fission during asexual blood stages
Thakur, V.; Singh, S.; Rathore, S.; Muneer, A.; Islam, M.; Datta, G.; Banday, M.; Arora, P.; Hossain, M. E.; Jain, S.; Ali, S.; Mohmmed, A.
10.1101/2024.03.25.586598 — cell biology — Posted on 2024-03-26
1111 Cryo-electron tomography reveals postsynaptic nanoblocks in excitatory synapses
Sun, R.; Allen, J. P.; Wilson, L.; Haider, M.; Alten, B.; Zhou, Z.; Wang, X.; Zhou, Q.
10.1101/2023.05.12.540562 — neuroscience — Posted on 2024-03-26
1112 Sleep need driven oscillation of glutamatergic synaptic phenotype
Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.
10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-03-26
1113 Utilizing gene co-expression networks with the rat kidney TXG-MAPr tool to enhance safety assessment, biomarker identification and human translation
Kunnen, S. J.; Callegaro, G.; Sutherland, J. J.; Trairatphisan, P.; van Kessel, H.; Wijaya, L. S.; Chung, G.; Pye, K.; Goldstein, K. M.; Teague, C. R.; Fisher, C. P.; Saez-Rodriguez, J.; Brown, C.; Elmore, S. A.; Heinz-Taheny, K. M.; Stevens, J. L.; van de Water, B.
10.1101/2023.11.03.565444 — pharmacology and toxicology — Posted on 2024-03-26
1114 Tissue-resident NK cells support survival in pancreatic cancer through promotion of cDC1-CD8T activity
Go, S.; Demetriou, C.; Valenzano, G.; Hughes, S.; Lanfredini, S.; Ferry, H.; Arbe-Barnes, E.; Sivakumar, S.; Bashford-Rogers, R.; Middleton, M. R.; Mukherjee, S.; Morton, J.; Jones, K.; O'Neill, E.
10.1101/2023.10.14.562332 — cancer biology — Posted on 2024-03-26
1115 Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy
Revach, O.-Y.; Cicerchia, A. M.; Shorer, O.; Petrova, B.; Anderson, S.; Park, J.; Chen, L.; Mehta, A.; Wright, S. J.; McNamee, N.; Tal-Mason, A.; Cattaneo, G.; Tiwari, P.; Xie, H.; Sweere, J. M.; Cheng, L.-C.; Sigal, N.; Enrico, E.; Miljkovic, M.; Evans, S. A.; Nguyen, N.; Whidden, M. E.; Srinivasan, R.; Spitzer, M. H.; Sun, Y.; Sharova, T.; Lawless, A.; Michaud, W. A.; Rasmussen, M. Q.; Fang, J.; Palin, C.; Chen, F.; Wang, X.; Ferrone, C. R.; Lawrence, D. P.; Sullivan, R. J.; Liu, D.; Sachdeva, U. M.; Sen, D. R.; Flaherty, K. T.; Manguso, R. T.; Bod, L.; Kellis, M.; Boland, G. M.; Yizhak, K.;
10.1101/2024.02.12.579184 — cancer biology — Posted on 2024-03-26
1117 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening
Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.
10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-26
1119 Jag1 Insufficiency Disrupts Neonatal T Cell Differentiation and Impairs Hepatocyte Maturation, Leading to Altered Liver Fibrosis
Masek, J.; Filipovic, I.; Van Hul, N. K.; Belicova, L.; Jirouskova, M.; Oliveira, D. V.; Frontino, A. M.; Hankeova, S.; He, J.; Turetti, F.; Iqbal, A.; Cervenka, I.; Sarnova, L.; Verboven, E.; Brabec, T.; Bjorkstrom, N. K.; Gregor, M.; Dobes, J.; Andersson, E. R.
10.1101/2022.10.24.513578 — developmental biology — Posted on 2024-03-26
1120 Rapid structural analysis of bacterial ribosomes in situ
Powell, B. M.; Brant, T. S.; Davis, J. H.; Mosalaganti, S.
10.1101/2024.03.22.586148 — cell biology — Posted on 2024-03-26
1121 SPACe (Swift Phenotypic Analysis of Cells): an open-source, single cell analysis of Cell Painting data
Stossi, F.; Singh, P. K.; Marini, M.; Safari, K.; Szafran, A. T.; Rivera-Tostado, A.; Candler, C. D.; Mancini, M. G.; Mosa, E. A.; Bolt, M. J.; Labate, D.; Mancini, M. A.
10.1101/2024.03.21.586132 — cell biology — Posted on 2024-03-26
1122 circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
Okholm, T. L. H.; Kamstrup, A. B.; Nielsen, M. M.; Hollensen, A. K.; Graversgaard, M. L.; Sorensen, M. H.; Kristensen, L. S.; Vang, S.; Park, S. S.; Yeo, G. W.; Dyrskjot, L.; Kjems, J.; Pedersen, J. S.; Damgaard, C. K.
10.1101/2023.09.14.557527 — molecular biology — Posted on 2024-03-26
1123 Widespread Horizontal Gene Transfer Among Animal Viruses
Buck, C. B.; Welch, N. L.; Belford, A. K.; Varsani, A.; Pastrana, D. V.; Tisza, M. J.; Starrett, G. J.
10.1101/2024.03.25.586562 — microbiology — Posted on 2024-03-26
1124 Algorithms for a Commons Cell Atlas
Booeshaghi, A. S.; Galvez-Merchan, A.; Pachter, L.
10.1101/2024.03.23.586413 — bioinformatics — Posted on 2024-03-26
1125 Extensive long-range polycomb interactions and weak compartmentalization are hallmarks of human neuronal 3D genome
Pletenev, I. A.; Bazarevich, M.; Zagirova, D. R.; Kononkova, A. D.; Cherkasov, A. V.; Efimova, O. I.; Tiukacheva, E. A.; Morozov, K. V.; Ulianov, K. A.; Komkov, D.; Tvorogova, A. V.; Golimbet, V. E.; Kondratyev, N. V.; Razin, S. V.; Khaitovich, P.; Ulianov, S. V.; Khrameeva, E. A.
10.1101/2023.08.04.551939 — genomics — Posted on 2024-03-26
1126 Differences in polygenic associations with educational attainment between West and East Germany before and after reunification
Fraemke, D.; Willems, Y. E.; Okbay, A.; Wagner, G.; Tucker-Drob, E. M.; Harden, K. P.; Koellinger, P.; Raffington, L.
10.1101/2024.03.21.585839 — genetics — Posted on 2024-03-26
1130 Widespread Horizontal Gene Transfer Among Animal Viruses
Buck, C. B.; Welch, N. L.; Belford, A. K.; Varsani, A.; Pastrana, D. V.; Tisza, M. J.; Starrett, G. J.
10.1101/2024.03.25.586562 — microbiology — Posted on 2024-03-26
1138 Altered empathy processing in frontotemporal dementiaA task-based fMRI study
Lindberg, O.; Li, T.-Q.; Lind, C.; Vest, S.; Alm, O.; Stiernstedt, M.; Ericson, A.; B, N.; Hansson, O.; Harper, L.; Westman, E.; Graff, C.; Tsevis, T.; Mannfolk, P.; Fischer, H.; Nilsonne, G.; Petrovic, P.; Nyberg, L.; Wahlund, L.-O.; Santillo, A.
10.1101/2024.03.21.586051 — neuroscience — Posted on 2024-03-26
1139 2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons
Shi, J.; Nutkovich, B.; Kushinsky, D.; Rao, B. Y.; Herrlinger, S. A.; Mihaila, T. S.; Malina, K. C.-K.; OToole, C. K.; Conde Paredes, M. E.; Yong, H. C.; Varol, E.; Losonczy, A.; Spiegel, I.
10.1101/2024.03.21.586118 — neuroscience — Posted on 2024-03-26
1142 A network of interacting ciliary tip proteins with opposing activities imparts slow and processive microtubule growth
Saunders, H. A. J.; van den Berg, C. M.; Hoogebeen, R.; Schweizer, D.; Stecker, K. E.; Roepman, R.; Howes, S. C.; Akhmanova, A.
10.1101/2024.03.25.586532 — cell biology — Posted on 2024-03-26
1143 Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
Chen, K.-E.; Tillu, V. A.; Gopaldass, N.; Chowdhury, S. R.; Leneva, N.; Kovtun, O.; Ruan, J.; Guo, Q.; Ariotti, N.; Mayer, A.; Collins, B. M.
10.1101/2024.03.24.586500 — cell biology — Posted on 2024-03-26
1144 Have AI-Generated Texts from LLM Infiltrated the Realm of Scientific Writing? A Large-Scale Analysis of Preprint Platforms
Cheng, H.; Sheng, B.; Lee, A.; Chaudhary, V.; Atanasov, A. G.; Liu, N.; Qiu, Y.; Wong, T. Y.; Tham, Y.-C.; Zheng, Y.-F.
10.1101/2024.03.25.586710 — scientific communication and education — Posted on 2024-03-26
1146 Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Delta/+ mice hearts
Foo, B.; Amedei, H.; Kaur, S.; Jaawan, S.; Boshnakovska, A.; Gall, T.; de Boer, R. A.; Sillje, H. H. W.; Urlaub, H.; Rehling, P.; Lenz, C.; Lehnart, S. E.
10.1101/2024.03.21.586093 — cell biology — Posted on 2024-03-26
1147 Molecular motor tug-of-war regulates elongasome cell wall synthesis dynamics in Bacillus subtilis
Middlemiss, S.; Blandenet, M.; Roberts, D. M.; McMahon, A.; Grimshaw, J.; Edwards, J. M.; Sun, Z.; Whitley, K. D.; Blu, T.; Strahl, H.; Holden, S.
10.1101/2023.05.10.540107 — microbiology — Posted on 2024-03-26
1148 CD4+ T cells drive corneal nerve damage but are dispensable for corneal epitheliopathy development in dry eye disease
Vereertbrugghen, A.; Pizzano, M.; Cernutto, A.; Sabbione, F.; Keitelman, I. A.; Vera Aguilar, D.; Podhorzer, A.; Fuentes, F.; Corral Vazquez, C.; Guzman, M.; Giordano, M. N.; Trevani, A. S.; de Paiva, C. S.; Galletti, J. G.
10.1101/2024.03.22.586336 — immunology — Posted on 2024-03-26
1149 Traumatic injury causes selective degeneration and TDP-43 mislocalization in human iPSC-derived C9orf72-associated ALS/FTD motor neurons
Martin, E. J.; Santacruz, C.; Mitevska, A.; Jones, I. E.; Krishnan, G.; Gao, F.-B.; Finan, J. D.; Kiskinis, E.
10.1101/2024.03.21.586073 — neuroscience — Posted on 2024-03-26
1150 Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer
Lee, S. U.; Cho, Y.; Li, Y.; Li, R.; Brown, D.; McAuliffe, P. F.; LEE, A. V.; Oesterreich, S.; Zervantonakis, I.; Osmanbeyoglu, H. U.
10.1101/2024.03.21.586041 — systems biology — Posted on 2024-03-26
1152 A chromosome-level genome assembly of the Hispid cotton rat (Sigmodon hispidus), a model for human pathogenic virus infections
Lilue, J.; Corvelo, A.; Gomez-Garrido, J.; Yang, F.; Akagi, K.; Green, G.; Ng, B. L.; Fu, B.; Chorostecki, U.; Warner, S. C.; Marcet-Houben, M.; Keane, T.; Mullikin, J. C.; Alioto, T.; Gabaldon, T.; Hubert, B.; Symer, D. E.; Niewiesk, S.
10.1101/2024.03.21.586163 — genomics — Posted on 2024-03-26
1155 CITE-seq analysis reveals human cytomegalovirus and diabetes-associated adaptive NK cell alterations in cardiovascular disease.
Armstrong, S. S.; Chen, D. G.; Kumar, S.; Heath, J. R.; Feinstein, M.; Greenland, J. R.; Calabrese, D. R.; Lanier, L. L.; Ley, K.; Shemesh, A.
10.1101/2024.03.22.581997 — immunology — Posted on 2024-03-26
1156 Detection and Removal of Hyper-synchronous Artifacts in Massively Parallel Spike Recordings
Oberste-Frielinghaus, J.; Morales-Gregorio, A.; Essink, S.; Kleinjohann, A.; Grun, S.; Ito, J.
10.1101/2024.01.11.575181 — neuroscience — Posted on 2024-03-26
1157 How Absence Seizures Impair Sensory Perception: Insights from Awake fMRI and Simulation Studies in Rats
Stenroos, P.; Guillemain, I.; Tesler, F.; Montigon, O.; Collomb, N.; Stupar, V.; Destexhe, A.; Coizet, V.; David, O.; Barbier, E. L.
10.1101/2023.07.26.550701 — neuroscience — Posted on 2024-03-26
1158 Unmasking Hidden Systemic Effects of Neurodegenerative Diseases: A Two-Pronged Approach to Biomarker Discovery
Anjo, S. I.; Rosado, M.; Baldeiras, I.; Gomes, A.; Pires, D.; Santa, C.; Pinto, J.; Januario, C.; Santana, I.; Verdelho, A.; Mendonca, A. d.; Castelo-Branco, M.; Manadas, B.
10.1101/2023.11.23.568435 — biochemistry — Posted on 2024-03-26
1161 A dual function of the IDA peptide in regulating cell separation and modulating plant immunity at the molecular level
Lalun, V. O.; Breiden, M.; Galindo-Trigo, S.; Smakowska-Luzan, E.; Simon, R.; Butenko, M. A.
10.1101/761346 — plant biology — Posted on 2024-03-26
1163 Mitochondrial genome variation affects humoral and cell-mediated innate immune responses and infection outcomes
Salminen, T. S.; Vesala, L.; Basikhina, Y.; Kutzer, M.; Tuomela, T.; Lucas, R.; Monteith, K.; Prakash, A.; Tietz, T.; Vale, P. F.
10.1101/2022.07.19.500574 — immunology — Posted on 2024-03-26
1164 Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia
Monzel, M.; Leelaarporn, P.; Lutz, T.; Schultz, J.; Brunheim, S.; Reuter, M.; McCormick, C.
10.1101/2023.08.11.552915 — neuroscience — Posted on 2024-03-26
1166 A high-resolution map of functional miR-181 response elements in the thymus reveals the role of coding sequence targeting and an alternative seed match
Verheyden, N. A.; Klostermann, M.; Bruggemann, M.; Steede, H. M.; Scholz, A.; Amr, S.; Lichtenthaeler, C.; Munch, C.; Schmid, T.; Zarnack, K.; Krueger, A.
10.1101/2023.09.08.556730 — immunology — Posted on 2024-03-26
1167 VaccineDesigner: A Web-based Tool for Streamlined Epitope-based Vaccine Design
Trygoniaris, D.; Anna, K.; Paraskeva, A.; Dhusku, E.; Tzimagiorgis, G.; Yiangou, M.; Kotzamanidis, C.; Malousi, A.
10.1101/2024.03.20.585850 — bioinformatics — Posted on 2024-03-26
1170 Acoustic inspired brain-to-sentence decoder for logosyllabic language
Feng, C.; Cao, L.; Wu, D.; Zhang, E.; Wang, T.; Jiang, X.; Zhou, C.; Chen, J.; Wu, H.; Lin, S.; Hou, Q.; Yang, J.; Lin, C.-T.; Zhu, J.; Sawan, M.; Zhang, Y.
10.1101/2023.11.05.562313 — neuroscience — Posted on 2024-03-26
1171 Arabidopsis transcriptome responses to low water potential using high throughput plate assays
Gonzalez, S.; Swift, J.; Yaaran, A.; Xu, J.; Miller, C.; Illouz-Eliaz, N.; Nery, J. R.; Zait, Y.; Busch, W.; Ecker, J. R.
10.1101/2022.11.25.517922 — plant biology — Posted on 2024-03-25
1172 Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors
Williams, K. B.; Larsson, A. T.; Keller, B. J.; Chaney, K. E.; Williams, R. L.; Jubenville, T. A.; Bhunia, M. M.; Draper, G. M.; Rathe, S. K.; Moertel, C. L.; Ratner, N.; Largaespada, D. A.
10.1101/2024.03.25.585959 — cancer biology — Posted on 2024-03-25
1173 Generative Adversarial Networks Accurately Reconstruct Pan-Cancer Histology from Pathologic, Genomic, and Radiographic Latent Features
Howard, F. M.; Hieromnimon, H.; Ramesh, S.; Dolezal, J.; Kochanny, S.; Zhang, Q.; Feiger, B.; Peterson, J.; Fan, C.; Perou, C.; Vickery, J. M.; Sullivan, M.; Cole, K.; Khramtsova, G.; Pearson, A. T.
10.1101/2024.03.22.586306 — cancer biology — Posted on 2024-03-25
1174 Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response
Hofer, S.; Frasch, L.; Putzker, K.; Lewis, J.; Sakhteman, A.; The, M.; Bayer, F. P.; Muller, J.; Hamood, F.; Kuster, B.
10.1101/2024.03.22.586243 — cancer biology — Posted on 2024-03-25
1175 Universal Cold RNA Phase Transitions
Rissone, P.; Severino, A.; Pastor del Campo, I.; Ritort Farran, F.
10.1101/2024.03.22.586224 — biophysics — Posted on 2024-03-25
1177 Influenza sequence validation and annotation using VADR
Calhoun, V. C.; Hatcher, E. L.; Yankie, L.; Nawrocki, E. P.
10.1101/2024.03.21.585980 — bioinformatics — Posted on 2024-03-25
1180 Analysis of the limited M. tuberculosis accessory genome reveals potential pitfalls of pan-genome analysis approaches
Marin, M. G.; Wippel, C.; Quinones-Olvera, N.; Behruznia, M.; Jeffrey, B. M.; Harris, M.; Mann, B. C.; Rosenthal, A.; Jacobson, K. R.; Warren, R. M.; Li, H.; Meehan, C. J.; Farhat, M. R.
10.1101/2024.03.21.586149 — bioinformatics — Posted on 2024-03-25
1181 MOTL: enhancing multi-omics matrix factorization with transfer learning
Hirst, D.; Terezol, M.; Cantini, L.; Villoutreix, P.; Vignes, M.; Baudot, A.
10.1101/2024.03.22.586210 — bioinformatics — Posted on 2024-03-25
1183 Robust diagnosis of infectious disease, autoimmunity and cancer from the paratope networks of adaptive immune receptors
Xu, Z.; Ismanto, H. S.; Saputri, D. S.; Haruna, S.; Sun, G.; Wilamowski, J.; Teraguchi, S.; Sengupta, A.; Standley, D. M.
10.1101/2023.11.28.569125 — bioinformatics — Posted on 2024-03-25
1185 Self-organization of vascularized skeletal muscle from bovine embryonic stem cells
Sanaki-Matsumiya, M.; Villava, C.; Rappez, L.; Haase, K.; Wu, J.; Ebisuya, M.
10.1101/2024.03.22.586252 — bioengineering — Posted on 2024-03-25
1186 Functional metagenomics reveals an alternative, broad-specificity pathway for metabolism of carbohydrates in human gut commensal bacteria
Nasseri, S. A.; Lazarski, A. C.; Lemmer, I. L.; Zhang, C. Y.; Brencher, E.; Chen, H.-M.; Sim, L.; Betschart, L.; Worral, L. J.; Strynadka, N. C. J.; Withers, S. G.
10.1101/2024.03.25.586180 — biochemistry — Posted on 2024-03-25
1188 A multi-tissue de novo transcriptome assembly and relative gene expression of the vulnerable freshwater salmonid Thymallus ligericus
Secci-Petretto, G.; Weiss, S. J.; Gomes-dos-Santos, A.; Persat, H.; Machado, A. M.; Vasconcelos, I.; Castro, L. F.; Froufe, E.
10.1101/2024.03.21.586089 — genomics — Posted on 2024-03-25
1189 SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis
Breunig, K.; Lei, X.; Montalbano, M.; Guardia, G.; Ostadrahimi, S.; Alers, V.; Kosti, A.; Chiou, J.; Klein, N.; Vinarov, C.; Wang, L.; Li, M.; Song, W.; Kraus, W. L. O.; Libich, D. S.; Tiziani, S.; Weintraub, S. T.; Galante, P. A. F.; Penalva, L. O.
10.1101/2024.03.22.586270 — genomics — Posted on 2024-03-25
1190 Unveiling the genetic blueprint of a desert scorpion: A chromosome-level genome of Hadrurus arizonensis provides the first reference for Parvorder Iurida
Bryant, M. J.; Coello, A. M.; Glendening, A. M.; Hilliman, S. A.; Jara, C. F.; Pring, S. S.; Rivera, A. R.; Santiago Membreno, J.; Nigro, L.; Pauloski, N.; Graham, M. R.; King, T.; Jockusch, E. L.; O'Neill, R. J.; Wegrzyn, J. L.; Santibanez-Lopez, C. E.; Webster, C. N.
10.1101/2024.03.22.586284 — genomics — Posted on 2024-03-25
1191 Unexpectedly low recombination rates and presence of hotspots in termite genomes
Everitt, T.; Ronneburg, T.; Elsner, D.; Olsson, A.; Liu, Y.; Larva, T.; Korb, J.; Webster, M. T.
10.1101/2024.03.22.586269 — genomics — Posted on 2024-03-25
1193 Characterization of Genome-wide Phylogenetic Conflict Uncovers Evolutionary Modes of Carnivorous Fungi
Zhang, W.; Fan, Y.; Deng, W.; Chen, Y.; Wang, S.; Kang, S.; Steenwyk, J. L.; Xiang, M.; Liu, X.
10.1101/2024.03.21.586083 — evolutionary biology — Posted on 2024-03-25
1194 The refinement paradox and cumulative cultural evolution: collective improvement in knowledge favors conformity, blind copying and hyper-credulity
Miu, E.; Rendell, L.; Bowles, S.; Boyd, R.; Cownden, D.; Enquist, M.; Eriksson, K.; Feldman, M. W.; Lillicrap, T.; McElreath, R.; Murray, S.; Ounsley, J.; Lala, K. N.
10.1101/2024.03.22.586239 — evolutionary biology — Posted on 2024-03-25
1195 Reassembly of a tropical rainforest ecosystem: A new chronosequence in the Ecuadorian Choco tested with the recovery of tree attributes
Escobar, S.; Newell, F. L.; Endara, M.-J.; Guevara-Andino, J. E.; Landim, A. R.; Neuschulz, E. L.; Nusser, R.; Müller, J.; Pedersen, K. M.; Schleuning, M.; Tremlett, C. J.; Villa-Galaviz, E.; Schaefer, H. M.; Donoso, D. A.; Blüthgen, N.
10.1101/2024.03.21.586145 — ecology — Posted on 2024-03-25
1197 Gag proteins encoded by endogenous retroviruses are required for zebrafish development
Chang, N.-C.; Wells, J. N.; Wang, A. Y.; Schofield, P.; Huang, Y.-C.; Truong, V. H.; Simoes-Costa, M.; Feschotte, C.
10.1101/2024.03.25.586437 — developmental biology — Posted on 2024-03-25
1199 Preeclampsia in mice carrying fetuses with APOL1 risk variants
Yoshida, T.; Latt, K. Z.; Shrivastav, S.; Lu, H.; Reidy, K. J.; Charlton, J. R.; Zhao, Y.; Winkler, C. A.; Reznik, S. E.; Rosenberg, A. Z.; Kopp, J. B.
10.1101/2024.03.20.586039 — molecular biology — Posted on 2024-03-25
1201 Connectomic reconstruction of a cortical column
Sievers, M.; Motta, A.; Schmidt, M.; Yener, Y.; Loomba, S.; Song, K.; Bruett, J.; Helmstaedter, M.
10.1101/2024.03.22.586254 — neuroscience — Posted on 2024-03-25
1208 Modeling Molecular Mechanisms of Pirfenidone Interaction with Kinases
Wijewardhane, P.; Wells, A.; Muhoberac, M.; Leung, K. P.; Chopra, G.
10.1101/2024.03.22.586235 — systems biology — Posted on 2024-03-25
1212 An atlas of Brachypodium distachyon lateral root development
de Jesus Vieira Teixeira, C.; Bellande, K.; van der Schuren, A.; O'Connor, D.; Hardtke, C. S.; Vermeer, J.
10.1101/2024.03.25.586236 — plant biology — Posted on 2024-03-25
1215 Transcriptional landscape of the dorsal raphe serotonin neurons rendering stress resiliency
Andoh, C.; Otani, S.; Noguchi, T.; Hagiwara, M.; Nishitani, N.; Kawai, H.; Fukui, Y.; Koda, M.; Morishita, H.; Nomura, K.; Oki, M.; Hori, H.; Shirakawa, H.; Kaneko, S.; Nagayasu, K.
10.1101/2024.03.21.586199 — pharmacology and toxicology — Posted on 2024-03-25
1216 Spatial proteomics and transcriptomics of placenta accreta spectrum
Bartels, H. C.; Hameed, S.; Young, C.; Nabhan, M.; Downy, P.; Curran, K. M.; McCormack, J.; Fabre, A.; Kolch, W.; Zhernovkov, V.; Brennan, D. J.
10.1101/2024.03.21.585167 — bioinformatics — Posted on 2024-03-25
1217 Marine biofilms: cyanobacteria factories for the global oceans
cheng, Z.; Shun, Y.; Yingdong, L.; Jiawei, C.; Tong, W.; Ruojun, W.; Kun, Z.; Aifang, C.; Weiduo, H.; Hongbin, L.; Kurt O., K.; Wataru, I.; Pei-Yuan, Q.
10.1101/2024.03.25.586614 — microbiology — Posted on 2024-03-25
1218 Infection of human organoids supports an intestinal niche for Chlamydia trachomatis
Hovhannisyan, P.; Stelzner, K.; Keicher, M.; Paprotka, K.; Neyazi, M.; Pauzuolis, M.; Ali, W. M.; Rajeeve, K.; Bartfeld, S.; Rudel, T.
10.1101/2024.03.25.586552 — microbiology — Posted on 2024-03-25
1219 Cortical evidence accumulation for perceptual experience occurs irrespective of reports
Stockart, F.; Msheik, R.; Robin, A.; Jurkovicova, L.; Goueytes, D.; Rouy, M.; Marecek, R.; Hoffmann, D.; Mudrik, L.; Roman, R.; Brazdil, M.; Minotti, L.; Kahane, P.; Pereira, M.; Faivre, N.
10.1101/2024.03.20.585198 — neuroscience — Posted on 2024-03-25
1227 VaccineDesigner: A Web-based Tool for Streamlined Epitope-based Vaccine Design
Trygoniaris, D. G.; Anna, K.; Paraskeva, A.; Dhusku, E.; Tzimagiorgis, G.; Yiangou, M.; Kotzamanidis, C.; Malousi, A.
10.1101/2024.03.20.585850 — bioinformatics — Posted on 2024-03-25
1232 Pseudo-pac site sequences used by phage P22 in generalized transduction of Salmonella
Maier, J.; Gin, C.; Callahan, B.; Sheriff, E. K.; Duerkop, B. A.; Kleiner, M.
10.1101/2024.03.25.586692 — microbiology — Posted on 2024-03-25
1236 Defensive fungal symbiosis on insect hindlegs
Nishino, T.; Mukai, H.; Moriyama, M.; Hosokawa, T.; Tanahashi, M.; Tachikawa, S.; Nikoh, N.; Koga, R.; Fukatsu, T.
10.1101/2024.03.25.586038 — microbiology — Posted on 2024-03-25
1239 Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses
Warren, C.; Barbachano-Guerrero, A.; DuMont, V.; Stabell, A.; Dirasantha, O.; Yang, Q.; Sawyer, S. L.
10.1101/2023.11.13.566830 — microbiology — Posted on 2024-03-25
1240 Functional Diversity of Memory CD8 T Cells is Spatiotemporally Imprinted
Reina-Campos, M.; Monell, A.; Ferry, A.; Luna, V.; Cheung, K.; Galletti, G.; Scharping, N. E.; Takehara, K.; Quon, S.; Boland, B.; Lin, Y. H.; Wong, W. H.; Indralingam, C. S.; Yeo, G. W.; Chang, J. T.; Heeg, M.; Goldrath, A. W.
10.1101/2024.03.20.585130 — immunology — Posted on 2024-03-25
1241 Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity.
Cox, D. J.; Connolly, S. A.; Maoldomhnaigh, C. O.; Brugman, A. A.; Thomas, O. S.; Duffin, E.; O'Connell, F.; Phelan, J. J.; Gogan, K. M.; Gleeson, L. E.; Basdeo, S. A.; Keane, J.
10.1101/2024.03.20.585747 — immunology — Posted on 2024-03-25
1242 HIV envelope trimers and gp120 as immunogens to induce broadly neutralizing antibodies in cows
Altman, P. X.; Parren, M.; Sang, H.; Ozorowski, G.; Lee, W.-H.; Smider, V. V.; Wilson, I. A.; Ward, A. B.; Mwangi, W.; Burton, D. R.; Sok, D.
10.1101/2024.03.20.585065 — immunology — Posted on 2024-03-25
1247 A circadian transcriptional sub-network and EARLY FLOWERING 3 control timing of senescence and grain nutrition in bread wheat
Buckley, C. R.; Boyte, J. M.; Albiston, R. L.; Hyles, J.; Beasley, J. T.; Johnson, A. A.; Trevaskis, B.; Fournier-Level, A.; Haydon, M. J.
10.1101/2024.02.19.580927 — plant biology — Posted on 2024-03-25
1248 Systematic Evaluation of High-Throughput PBK Modelling Strategies for the Prediction of Intravenous and Oral Pharmacokinetics in Humans
Geci, R.; Gadaleta, D.; Garcia de Lomana, M.; Ortega-Vallbona, R.; Colombo, E.; Serrano-Candelas, E.; Paini, A.; Kuepfer, L.; Schaller, S.
10.1101/2024.03.20.585001 — pharmacology and toxicology — Posted on 2024-03-25
1252 μ-Opioid receptor transcriptional variants in the murine forebrain and spinal cord
Chroszcz, M.; Hajto, J.; Misiolek, K.; Szumiec, L.; Ziemianska, M.; Radlicka-Borysewska, A.; Borczyk, M.; Zieba, M.; Golda, S.; Siwiec, M.; Ziolkowska, B.; Piechota, M.; Korostynski, M.; Parkitna, J. M. R.
10.1101/2024.03.20.585849 — genomics — Posted on 2024-03-25
1254 Emergent time scales of epistasis in protein evolution
Di Bari, L.; Bisardi, M.; Cotogno, S.; Weigt, M.; Zamponi, F.
10.1101/2024.03.14.585034 — evolutionary biology — Posted on 2024-03-25
1255 Genetic causes and genomic consequences of breakdown of distyly in Linum trigynum
Gutierrez-Valencia, J.; Zervakis, P.-I.; Postel, Z.; Fracassetti, M.; Losvik, A.; Mehrabi, S.; Bunikis, I.; Soler, L.; Hughes, P. W.; Desamore, A.; Laenen, B.; Abdelaziz, M.; Vinnere Pettersson, O.; Arroyo, J.; Slotte, T.
10.1101/2023.11.16.567348 — evolutionary biology — Posted on 2024-03-25
1256 Mitochondria drive microglial NRLP3 inflammasome activation via TSPO
Singh, A.; Rigon, M.; Caldeira, M.; Faccenda, D.; Xia, D.; Lopez-Tremoleda, J.; Falah Hassan Al-Khateeb, Z.; Guo, T.; Abeti, R.; Giunti, P.; Campanella, M.
10.1101/2024.03.18.585507 — cell biology — Posted on 2024-03-25
1257 A continuum of CD4+ T cell 'help' defines Memory B cell fate
Pritchard, G. H.; Krishnamurty, A. T.; Rodda, L.; McDougal, C.; Shehata, L.; Pepper, M.
10.1101/564351 — immunology — Posted on 2024-03-25
1259 Gene expression plasticity of the mammalian brain circadian clock in response to photoperiod
Cox, O. H.; Giannoni-Guzman, M. A.; Cartailler, J.-P.; Cottam, M. A.; McMahon, D. G.
10.1101/2024.02.16.580759 — neuroscience — Posted on 2024-03-25
1260 Systemic inflammation triggers long-lasting neuroinflammation and accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein
Massaro Cenere, M.; Tiberi, M.; Paldino, E.; D'Addario, S. L.; Federici, M.; Giacomet, C.; Cutuli, D.; Matteocci, A.; Cossa, F.; Zarrilli, B.; Casadei, N.; Ledonne, A.; Petrosini, L.; Berretta, N.; Fusco, F. R.; Chiurchiu, V.; Mercuri, N. B.
10.1101/2024.01.30.577912 — neuroscience — Posted on 2024-03-25
1264 Sugar assimilation underlying dietary evolution of Neotropical bats
Camacho, J.; Bernal-Rivera, A.; Pena, V.; Morales-Sosa, P.; Robb, S.; Russell, J.; Yi, K.; Tsuchiya, D.; Wang, Y.; Murillo-Garcia, O. E.; Rohner, N.
10.1101/2023.07.02.547432 — evolutionary biology — Posted on 2024-03-25
1265 BCL11b interacts with RNA and proteins involved in RNA processing and developmental diseases
Sobhy, H.; De Rovere, M.; Ait-Ammar, A.; Kashif, M.; WALLET, C.; DAOUAD, F.; Loustau, T.; Van Lint, C.; SCHWARTZ, C.; ROHR, O.
10.1101/2020.11.05.369959 — developmental biology — Posted on 2024-03-25
1267 METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
Thombare, K.; Vaid, R.; Pucci, P.; Mendez, A.; Burgos-Panadero, R.; Ayyalusamy, R.; Rehan, A. A.; Baig, M. H.; Nale, S. D.; Bartenhagen, C.; Dong, J. j.; Fischer, M.; Turner, S. D.; Mondal, T.
10.1101/2023.10.06.561194 — cancer biology — Posted on 2024-03-25
1269 Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase
Diaz, R. E.; Ecker, A. K.; Correy, G. J.; Asthana, P.; Young, I. D.; Faust, B.; Thompson, M. C.; Seiple, I. B.; Van Dyken, S. J.; Locksley, R. M.; Fraser, J. S.
10.1101/2023.06.03.542675 — biochemistry — Posted on 2024-03-25
1270 Diverse Database and Machine Learning Model to narrow the generalization gap in RNA structure prediction
Rouskn, S.; de Lajarte, A.; Martin Des Taillades, Y.; Kalicki, C.; Fuchs, F.; Aruda, J.; Salazar, D.; Allan, M.; LEsperance-Kerckhoff, C.; Kashi, A.; Jossinet, F.
10.1101/2024.01.24.577093 — biochemistry — Posted on 2024-03-25
1273 Jag1 Insufficiency Disrupts Neonatal T Cell Differentiation and Impairs Hepatocyte Maturation, Leading to Altered Liver Fibrosis
Masek, J.; Filipovic, I.; Van Hul, N. K.; Belicova, L.; Jirouskova, M.; Oliveira, D. V.; Frontino, A. M.; Hankeova, S.; He, J.; Turetti, F.; Iqbal, A.; Cervenka, I.; Sarnova, L.; Verboven, E.; Brabec, T.; Bjorkstrom, N. K.; Gregor, M.; Dobes, J.; Andersson, E. R.
10.1101/2022.10.24.513578 — developmental biology — Posted on 2024-03-25
1274 A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
Maher, S. P.; Bakowski, M. A.; Vantaux, A.; Flannery, E. L.; Andolina, C.; Gupta, M.; Antonova-Koch, Y.; Argomaniz, M.; Monica, C.-M.; Brice, C.; Chao, A. T.; Chatterjee, A. K.; Cheng, W. T.; Chuenchob, E.; Cooper, C. A.; Karissa, C.; Galinski, M. R.; Harupa-Chung, A.; Ji, H.; Joseph, S. B.; Lenz, T.; Lonardi, S.; Matheson, J.; Mikolajczak, S. A.; Timothy, M.; Orban, A.; Padin-Irizarry, V.; Pan, K.; Peneau, J.; Prudhomme, J.; Roesch, C.; Ruberto, A. A.; Sabnis, S. S.; Saney, C. L.; Sattabongkot, J.; Sereshki, S.; Suriyakan, S.; Ubalee, R.; Wang, Y.; Wasisakun, P.; Yin, J.; Popovici, J.; McNama
10.1101/2023.01.31.526483 — cell biology — Posted on 2024-03-25
1275 Homeostasis of a representational map in the neocortex
Noda, T.; Kienle, E.; Eppler, J.-B.; Aschauer, D. F.; Kaschube, M.; Loewenstein, Y.; Rumpel, S.
10.1101/2023.06.13.544358 — neuroscience — Posted on 2024-03-25
1276 Development of an ultrafast pulsed ponderomotive phase plate for cryo-electron tomography
Du, D. X.; Bartnik, A. C.; Duncan, C. J. R.; Choudhry, U.; Tabachnik, T.; Sallah, C.; Najafi, E.; Yang, D.-S.; Maxson, J. M.; Fitzpatrick, A. W. P.
10.1101/2024.03.20.585981 — biophysics — Posted on 2024-03-25
1280 Animal group size variation in a minimal attraction-repulsion agent-based model
Eikelboom, J. A. J.; Doelman, A.; Van Langevelde, F.; De Knegt, H. J.
10.1101/2024.03.20.585938 — ecology — Posted on 2024-03-25
1281 Social network centrality predicts dietary decisions in a wild bird population
McMahon, K.; Marples, N. M.; Spurgin, L. G.; Rowland, H. M.; Sheldon, B. S.; Firth, J. A.
10.1101/2023.08.25.554636 — ecology — Posted on 2024-03-25
1285 Selective deletion of interleukin-1 alpha in microglia regulates neuronal activity and neurorepair processes after experimental ischemic stroke.
Lemarchand, E.; Grayston, A.; Wong, R.; Rogers, M.; Ouvrier, B.; Llewellyn, B.; Webb, F.; Lenart, N.; Denes, A.; Brough, D.; Allan, S. M.; Bix, G.; Pinteaux, E.
10.1101/2024.02.16.580635 — neuroscience — Posted on 2024-03-25
1286 RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity
Singh, S.; Fang, J.; Jin, H.; Van de Velde, L.-A.; Wu, Q.; Cortes, A.; Morton, C.; Woolard, M.; Quarni, W.; Steele, J.; Connelly, J.; He, L.; Thorne, R.; Turner, G.; Confer, T.; Johnson, M.; Caufield, W.; Freeman, B.; Lockey, T.; Pruett-Miller, S.; Wang, R.; Davidoff, A.; Thomas, P.; Yang, J.
10.1101/2024.03.21.586157 — cancer biology — Posted on 2024-03-25
1288 PHARAOH: A collaborative crowdsourcing platform for PHenotyping And Regional Analysis Of Histology
Faust, K.; Chen, M. L.; Zadeh, P. B.; Oreopoulos, D. G.; Leon, A. J.; Kamski-Hennekam, E.; Mikhail, M.; Duan, X.; Duan, X.; Liu, M.; Ahangari, N.; Cotau, R.; Castillo, V. F.; Nikzad, N.; Sugden, R. J.; Murphy, P.; Done, S.; Aljohani, S. S.; Echelard, P.; Jakate, K.; Alwelaie, Y.; Alyousef, M. J.; Alsafwani, N. S.; Alrumeh, A. S.; Saleeb, R.; Richer, M.; Marins, L. V.; Yousef, G. M.; Diamandis, P.
10.1101/2024.03.20.585977 — bioinformatics — Posted on 2024-03-25
1292 Mitochondrial stress in GABAergic neurons non-cell autonomously regulates organismal health and aging
Rathor, L.; Curry, S.; Park, Y.; McElroy, T.; Robles, B.; Yi, S.; Chen, W.-W.; Min, K.; Xiao, R.; Lee, M. H.; Han, S. M.
10.1101/2024.03.20.585932 — genetics — Posted on 2024-03-25
1293 Extended culture of 2D gastruloids to model human mesoderm development
Chen, B.; Khan, H.; Yu, Z.; Yao, L.; Freeburne, E.; Jo, K.; Johnson, C.; Heemskerk, I.
10.1101/2024.03.21.585753 — developmental biology — Posted on 2024-03-25
1296 Sensory integration of food availability and population density during the diapause exit decision involves insulin-like signaling in Caenorhabditis elegans
Zhang, M. G.; Seyedolmohadesin, M.; Mercado, S. H.; Park, H.; Finnen, N.; Schroeder, F. C.; Venkatachalam, V.; Sternberg, P. W.
10.1101/2024.03.20.586022 — neuroscience — Posted on 2024-03-25
1298 Effects of nano urea on growth and gene expression of Arabidopsis thaliana in hydroponics
JANGID, N.; MARIK, D.; VERMA, D.; DEY, A.; SHEKHAWAT, R. S.; PATEL, D.; YADAV, P.; SANKHALA, K.; SADHUKHAN, A.
10.1101/2024.03.20.585664 — plant biology — Posted on 2024-03-25
1299 A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan
Jayne, L.; Lavin-Peter, A.; Roessler, J.; Tyshkovskiy, A.; Antoszewski, M.; Ren, E.; Markovski, A.; Sun, S.; Yao, H.; Sankaran, V. G.; Gladyshev, V. N.; Brooke, R. T.; Horvath, S.; Griffith, E. C.; Hrvatin, S.
10.1101/2024.03.20.585828 — physiology — Posted on 2024-03-25
1300 Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3
Berenger, S.; Adamska, J. M.; Deflorian, F.; de Graaf, C.; Palmer, C. B.; Szpakowska, M.; Chevigne, A.; de Esch, I. J. P.; Zarzycka, B.; Vischer, H. F.; Wijtmans, M.; Leurs, R.
10.1101/2024.03.20.585914 — pharmacology and toxicology — Posted on 2024-03-25
1301 Machine learning predicts lifespan and underlying causes of death in aging C. elegans
Kern, C.; Manescu, P.; Cuffaru, M.; Au, C.; Zhange, A.; Wang, H.; Gilliat, A. F.; Ezcurra, M.; Gems, D.
10.1101/2024.03.20.585803 — genetics — Posted on 2024-03-25
1302 A high-throughput zebrafish screen identifies novel candidate treatments for Kaposiform Lymphangiomatosis (KLA)
Bassi, I.; Jabali, A.; Farag, N.; Egozi, S.; Moshe, N.; Leichner, G. S.; Geva, P.; Levin, L.; Barzilai, A.; Avivi, C.; Long, J.; Otterstrom, J. J.; Paran, Y.; Barr, H.; Yaniv, K.; Greenberger, S.
10.1101/2024.03.21.586124 — developmental biology — Posted on 2024-03-25
1305 Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways
Quirion, L.; Robert, A.; Boulais, J.; Huang, S.; Bernal Astrain, G.; Strakhova, R.; Jo, C. H.; Kherdjemil, Y.; Thibault, M.-P.; Faubert, D.; Kmita, M.; Baskin, J. M.; Gingras, A.-C.; Smith, M. J.; Cote, J.-F.
10.1101/2023.03.01.530598 — molecular biology — Posted on 2024-03-25
1306 sgRNA constraints and genetic limitations for efficient Cas9 genome editing to generate knock-outs
Haussmann, I. U.; Dix, T. C.; McQuarrie, D. W.; Dezi, V.; Hans, A. I.; Arnold, R.; Soller, M.
10.1101/2022.12.15.520550 — molecular biology — Posted on 2024-03-25
1307 Decoding the Cognitive map: Learning place cells and remapping
Pettersen, M. B.; Schoyen, V. S.; Malthe-Sorenssen, A.; Lepperod, M. E.
10.1101/2024.03.14.585049 — neuroscience — Posted on 2024-03-25
1309 Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells
Gonschorek, D.; Goldin, M. A.; Oesterle, J.; Schwerd-Kleine, T.; Arlinghaus, R.; Zhao, Z.; Schubert, T.; Marre, O.; Euler, T.
10.1101/2023.12.23.572742 — neuroscience — Posted on 2024-03-25
1310 scATAnno: Automated Cell Type Annotation for single-cell ATAC Sequencing Data
Jiang, Y.; Hu, Z.; Lynch, A. W.; Jiang, J.; Zhu, A.; Zhang, Y.; Xie, Y.; Li, R.; Zhou, N.; Meyer, C. A.; Cejas, P.; Brown, M.; Long, H. W.; Qiu, X.
10.1101/2023.06.01.543296 — bioinformatics — Posted on 2024-03-25
1311 Allele frequency dynamics under sex-biased demography and sex-specific inheritance in a pedigreed jay population
Driscoll, R. M. H.; Beaudry, F. E. G.; Cosgrove, E. J.; Fitzpatrick, J. W.; Schoech, S. J.; Chen, N.
10.1101/2021.10.28.466320 — evolutionary biology — Posted on 2024-03-25
1315 MSK1 absence hinders BDNF-dependent striatal neurodevelopment and leads to schizophrenia symptoms
Varela-Andres, N.; Cebrian-Leon, A.; Hernandez-del Cano, C.; Fernandez-del Campo, I. S.; Garcia-Losada, S.; Martin-Avila, N.; Arevalo, J. C.; Merchan, M.; Sanchez-Martin, M. A.; Deogracias, R.
10.1101/2024.01.23.576945 — neuroscience — Posted on 2024-03-25
1317 Acute multi-level response to defective de novo chromatin assembly in S-phase
Dreyer, J.; Ricci, G.; van den Berg, J.; Bhardwaj, V.; Funk, J.; Armstrong, C.; van Batenburg, V.; Sine, C.; Vaninsberghe, M. A.; Marsman, R.; Mandemaker, I. K.; di Sanzo, S.; Costantini, J.; Manzo, S.; Biran, A.; Burny, C.; Voelker-Albert, M.; Groth, A.; Spencer, S. L.; van Oudenaarden, A.; Mattiroli, F.
10.1101/2024.03.22.586291 — cell biology — Posted on 2024-03-25
1321 Chainsaw: protein domain segmentation with fullyconvolutional neural networks
Wells, J.; Hawkins-Hooker, A.; Bordin, N.; Sillitoe, I.; Paige, B.; Orengo, C.
10.1101/2023.07.19.549732 — molecular biology — Posted on 2024-03-25
1322 Exploring Motor Network Connectivity in State-Dependent Transcranial Magnetic Stimulation: A Proof-of-Concept Study
Marzetti, L.; Basti, A.; Guidotti, R.; Baldassarre, A.; Metsomaa, J.; Zrenner, C.; D'Andrea, A.; Makkinayeri, S.; Pieramico, G.; Ilmoniemi, R. J.; Ziemann, U.; Romani, G. L.; Pizzella, V.
10.1101/2023.06.29.547027 — neuroscience — Posted on 2024-03-25
1323 On the mechanism for winter stem pressure build-up in walnut trees
Bozonnet, C.; Saudreau, M.; Badel, E.; Charrier, G.; Ameglio, T.
10.1101/2023.12.21.572762 — plant biology — Posted on 2024-03-25
1324 HyperPRI: A Dataset of Hyperspectral Images for Underground Plant Root Study
Chang, S. J.; Chowdhry, R.; Song, Y.; Mejia, T.; Hampton, A.; Kucharski, S.; Sazzad, T.; Zhang, Y.; Koppal, S. J.; Wilson, C. H.; Gerber, S.; Tillman, B.; Resende, M. F.; Hammond, W. M.; Zare, A.
10.1101/2023.09.29.559614 — plant biology — Posted on 2024-03-25
1325 GFPrint™: A MACHINE LEARNING TOOL FOR TRANSFORMING GENETIC DATA INTO CLINICAL INSIGHTS
Sanz-Martin, G.; Migliore, D. P.; Gomez del Campo, P.; del Castillo-Izquierdo, J.; Dominguez, J. M.
10.1101/2024.03.08.584090 — bioinformatics — Posted on 2024-03-25
1326 The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics
Mc Cartney, A. M.; Formenti, G.; Mouton, A.; De Panis, D.; Marins, L. S.; Leitao, H. G.; Diedericks, G.; Kirangwa, J.; Morselli, M.; Salces, J.; Escudero, N.; Iannucci, A.; Natali, C.; Svardal, H.; Fernandez, R.; De Pooter, T.; Joris, G.; Strazisar, M.; Wood, J.; Herron, K. E.; Seehausen, O.; Watts, P. C.; Shaw, F.; Davey, R. P.; Minotto, A.; Fernandez Gonzalez, J. M.; Bohne, A.; Alegria, C.; Alioto, T.; Alves, P. C.; Amorim, I. R.; Aury, J.-M.; Backstrom, N.; Baldrian, P.; Ballarin, L.; Baltrunaite, L.; Barta, E.; BedHom, B.; Belser, C.; Bergsten, J.; Bertrand, L.; Bilandija, H.; Binzer-Panch
10.1101/2023.09.25.559365 — genomics — Posted on 2024-03-25
1327 Reproductive modes of polyploid Ludwigia grandiflora subsp. hexapetala in western Europe: the effects of a late-acting self-incompatibility system and its absence on genetic diversity within populations
stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.
10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-03-25
1329 Within-host viral growth and immune response rates predict FMDV transmission dynamics for African Buffalo
Macdonald, J. C.; Gulbudak, H.; Beechler, B.; Gorsich, E.; Gubbins, S.; Perez-Martin, E.; Jolles, A.
10.1101/2022.12.02.518883 — ecology — Posted on 2024-03-25
1336 Deep Divergences Among Inconspicuously Colored Clades of Epipedobates Poison Frogs
Lopez-Hervas, K.; Santos, J. C.; Ron, S. R.; Betancourth-Cundar, M.; Cannatella, D. C.; Tarvin, R. D.
10.1101/2023.06.29.547117 — evolutionary biology — Posted on 2024-03-24
1338 Differential gene expression and chromatin accessibility in the medial prefrontal cortex associated with individual differences in rat behavioral models of opioid use disorder
Liu, S. X.; Muelken, P.; Maxim, Z. L.; Ramakrishnan, A.; Estill, M. S.; LeSage, M. G.; Smethells, J. R.; Shen, L.; Tran, P. V.; Harris, A. C.; Gewirtz, J. C.
10.1101/2024.02.29.582799 — neuroscience — Posted on 2024-03-24
1341 Design of a sequestration-based network with tunable pulsing dynamics
Nakamura, E.; Cuba Samaniego, C.; Blanchini, F.; Giordano, G.; Franco, E.
10.1101/2024.03.24.586474 — synthetic biology — Posted on 2024-03-24
1342 Conversion of natural cytokine receptors into orthogonal synthetic biosensors
Edelstein, H. I.; Cosio, A.; Ezekiel, M. L.; Corcoran, W. K.; Morris, A. H.; Leonard, J. N.
10.1101/2024.03.23.586421 — synthetic biology — Posted on 2024-03-24
1344 Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells
Berezovsky, A. D.; Nuga, O.; Datta, I.; Bergman, K.; Sabedot, T.; Gurdziel, K.; Irtenkauf, S.; Hasselbach, L.; Meng, Y.; Mueller, C.; Petricoin, E.; Brown, S.; Purandare, N.; Aras, S.; Mikkelsen, T.; Poisson, L.; Noushmehr, H.; Ruden, D. M.; deCarvalho, A.
10.1101/2024.03.14.585115 — cancer biology — Posted on 2024-03-24
1345 Modeling Allosteric Mechanisms of Eukaryotic Type II Topoisomerases
Evoli, S.; Kariyawasam, N. L.; Nitiss, K. C.; Nitiss, J. L.; Wereszczynski, J.
10.1101/2023.08.02.551689 — biophysics — Posted on 2024-03-24
1347 Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K promotes starvation resistance by preventing oxidative damage in C. elegans
Yan, J.; Bhanshali, F.; Shuzenji, C.; Mendenhall, T. T.; Cheng, X.; Bai, P.; Diwan, G.; Seraj, D.; Meyer, J. N.; Sorensen, P. H.; Hartman, J. H.; Taubert, S.
10.1101/2024.03.20.585993 — genetics — Posted on 2024-03-24
1348 Unveiling the control of N and P on DOM fate in a Mediterranean coastal environment
Dignan, C.; Lenoble, V.; Santinelli, C.; Bachi, G.; Dang, D. H.; Garcia, N.; Misson, B.
10.1101/2024.03.20.585141 — ecology — Posted on 2024-03-24
1349 Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions
Burns, G. W.; Fu, Z.; Vegter, E. L.; Madaj, Z. B.; Greaves, E.; Flores, I.; Fazleabas, A. T.
10.1101/2024.03.23.586434 — molecular biology — Posted on 2024-03-24
1355 Defining the constituents and functions of a lipid-based jumbo phage compartment
Mozumdar, D.; Fossati, A.; Stevenson, E.; Guan, J.; Nieweglowska, E. S.; Rao, S.; Agard, D.; Swaney, D. L.; Bondy-Denomy, J.
10.1101/2024.03.24.586471 — microbiology — Posted on 2024-03-24
1356 Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor
Oshima, H. S.; Ogawa, A.; Sano, F. K.; Akasaka, H.; Kawakami, T.; Okamoto, H. H.; Iwama, A.; Nagiri, C.; Wei, F.-Y.; Shihoya, W.; Nureki, O.
10.1101/2024.03.23.586386 — biophysics — Posted on 2024-03-24
1358 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening
Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.
10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-24
1362 Signal-independent activation reveals two-component regulatory networks
Claverie, C.; Coppolino, F.; Mazzuoli, M.-V.; Guyonnet, C.; Jacquemet, E.; Legendre, R.; Sismeiro, O.; De Gaetano, G. V.; Teti, G.; Trieu-Cuot, P.; Tazi, A.; Beninati, C.; Firon, A.
10.1101/2024.03.22.586261 — microbiology — Posted on 2024-03-24
1363 Surface Hydrophilicity Promotes Bacterial Twitching Motility
O'Hara, M. T.; Dye, K. J.; Shimozono, T.; Harris, D.; Yang, Z.
10.1101/2024.03.23.586342 — microbiology — Posted on 2024-03-24
1366 Endogenous CD28 drives CAR T cell responses in multiple myeloma
Lieberman, M. M.; Tong, J. H.; Odukwe, N. U.; Chavel, C. A.; Purdon, T. J.; Burchett, R.; Gillard, B. M.; Brackett, C. M.; McGray, A. R.; Bramson, J. L.; Brentjens, R. J.; Lee, K. P.; Olejniczak, S. H.
10.1101/2024.03.21.586084 — cancer biology — Posted on 2024-03-24
1367 Functional Protein Dynamics in a Crystal
Klyshko, E.; Kim, J. S.-H.; McGough, L.; Valeeva, V.; Lee, E.; Ranganathan, R.; Rauscher, S.
10.1101/2023.07.06.548023 — biophysics — Posted on 2024-03-24
1368 Bilingual Language Model for Protein Sequence and Structure
Heinzinger, M.; Weissenow, K.; Gomez Sanchez, J.; Henkel, A.; Mirdita, M.; Steinegger, M.; Rost, B.
10.1101/2023.07.23.550085 — bioinformatics — Posted on 2024-03-24
1369 Towards a Biohybrid Lung? Impacted Endothelial Layer Integrity in Inflammatory Conditions
Cheremkhina, M.; Babendreyer, A.; Neullens, C. T.; Krapp, S.; Pabst, A.; Ohl, K.; Tenbrock, K.; Ruetten, S.; Ludwig, A.; Cornelissen, C. G.; Thiebes, A. L.; Jockenhoevel, S.
10.1101/2023.10.31.564901 — bioengineering — Posted on 2024-03-24
1370 Integrative Omics reveals changes in the cellular landscape of yeast without peroxisomes
Kosir, T.; Das, H.; Pedersen, M. P.; Anteghini, M.; Oeljeklaus, S.; Martins dos Santos, V.; van der Klei, I. J.; Warscheid, B.
10.1101/2024.03.20.585854 — cell biology — Posted on 2024-03-24
1371 Chaperone-Mediated Autophagy in Fish: A Key Function Amid a Changing Environment
Schnebert, S.; Velez, E. J.; Goguet, M.; Dias, K.; Veron, V.; Garcia-Perez, I.; Radler, L. M.; Cardona, E.; Fontagne-Dicharry, S.; Van-Delft, P.; Dittrich-Domergue, F.; Bernard, A.; Beaumatin, F.; Herpin, A.; Cleveland, B.; Seiliez, I.
10.1101/2024.03.20.585855 — cell biology — Posted on 2024-03-24
1372 The common TMEM173 HAQ, AQ alleles rescue CD4 T cellpenia, restore T-regs, and prevent SAVI (N153S) inflammatory disease in mice.
Aybar-Torres, A. a.; saldarriaga, L. A.; Pham, A. T.; Emtiazjoo, A. M.; Sharma, A. K.; Bryant, A. J.; jin, l.
10.1101/2023.10.05.561109 — immunology — Posted on 2024-03-24
1376 Microbial communities thriving in agave fermentations are locally influenced across diverse biogeographic regions
Jara-Servin, A.; Alcaraz, L. D.; Juarez-Serrano, S. I.; Espinosa-Jaime, A.; Barajas, I.; Morales, L.; DeLuna, A.; Hernandez-Lopez, A.; Mancera, E.
10.1101/2024.03.22.586289 — microbiology — Posted on 2024-03-24
1378 First evaluation and detection of ivermectin resistance in gastrointestinal nematodes of sheep and goats in South Darfur, Sudan
Mohammedsalih, K. M.; Ibrahim, A. I. Y.; Juma, F.-R.; Abdalmalaik, A. A. H.; Bashar, A.; Coles, G.; von Samson-Himmelstjerna, G.; Krücken, J.
10.1101/2024.03.20.585868 — zoology — Posted on 2024-03-24
1380 Immune gene expression changes more during a malaria transmission season than between consecutive seasons.
Tebben, K.; Yirampo, S.; Coulibaly, D.; Kone, A. K.; Laurens, M. B.; Stucke, E. M.; Dembele, A.; Tolo, Y.; Traore, K.; Niangaly, A.; Berry, A. A.; Kouriba, B.; Plowe, C. V.; Doumbo, O. K.; Lyke, K. E.; Takala-Harrison, S.; Thera, M. A.; Travassos, M. A.; Serre, D.
10.1101/2024.03.20.585963 — bioinformatics — Posted on 2024-03-24
1381 Latest RNA and DNA nanopore sequencing allows for rapid avian influenza profiling
Perlas, A.; Reska, T.; CROVILLE, G.; Tarres-Freixas, F.; Guerin, J.-L.; Majo, N.; Urban, L.
10.1101/2024.02.28.582540 — genomics — Posted on 2024-03-24
1383 Alstrom syndrome proteins regulate centriolar cartwheel assembly by enabling Plk4-Ana2 amplification loop in Drosophila
Brunet, M.; Thomas, J.; Lapart, J.-A.; Krüttli, L.; Laporte, M.; Riparbelli, M. G.; Callaini, G.; Durand, B.; Morel, V.
10.1101/2023.09.13.557518 — cell biology — Posted on 2024-03-24
1384 The SMC5/6 complex is required for maintenance of genome integrity upon APOBEC3A-mediated replication stress
O'Leary, D. R.; Hansen, A. R.; Fingerman, D. F.; Tran, T. A.; Harris, B. R.; Hayer, K. E.; Fan, J.; Chen, E.; Tennekoon, M.; DeWeerd, R. A.; Meroni, A.; Szeto, J.; Weitzman, M. D.; Bednarski, J. J.; Shalem, O.; Vindigni, A.; Zhao, X.; Green, A. M.
10.1101/2023.11.28.568952 — molecular biology — Posted on 2024-03-24
1385 Hippocampal Dipeptidyl Peptidase 9 Bidirectionally Regulates Memory Via Synaptic Plasticity.
Zhao, Y.-B.; Wang, S.; Wang, L.; Guo, W.; Li, J. N.; Xun, T.; Xu, L.; Zhou, Q.-X.
10.1101/2023.11.02.565088 — neuroscience — Posted on 2024-03-24
1390 Alzheimer's disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Maksour, S.; Finol-Urdaneta, R. K.; Hulme, A. J.; Cabral-da-Silva, M. C.; Targa Dias Anastacio, H.; Balez, R.; Berg, T.; Turner, C.; Sanz Munoz, S.; Engel, M.; Kalajdzic, P.; Lisowski, L.; Sidhu, K.; Sachdev, P. S.; Dottori, M.; Ooi, L.
10.1101/2024.03.22.586207 — cell biology — Posted on 2024-03-23
1391 LncRNA-Snhg3 Aggravates Hepatic Steatosis by Regulating PPARγ via SND1/H3K27me3
Xie, X.; Gao, M.; Zhao, W.; Li, C.; Zhang, W.; Yang, J.; Zhang, Y.; Chen, E.; Guo, Y.; Guo, Z.; Zhang, M.; Ngowi, E. E.; Wang, H.; Wang, X.; Zhu, Y.; Wang, Y.; Li, X.; Yao, H.; Yan, L.; Fang, F.; Li, M.; Qiao, A.; Liu, X.
10.1101/2024.03.22.586335 — molecular biology — Posted on 2024-03-23
1393 Genetic elements and defense systems drive diversification and evolution in Asgard archaea
Valentin Alvarado, L. E.; Shi, L.-D.; Appler, K. E.; Crits-Christoph, A.; Cui, M. L.; De Anda, V.; Leao, P.; Adler, B. A.; Roberts, R. J.; Sachdeva, R.; Baker, B. J.; Savage, D. F.; Banfield, J.
10.1101/2024.03.22.586370 — microbiology — Posted on 2024-03-23
1394 Hepatitis E virus infection upregulates ING5 expression in vitro and vivo
Zhao, W.; Xia, Y.; Li, T.; Liu, H.; Zhong, G.; Chen, D.; Yu, W.; Li, Y.; Huang, F.
10.1101/2024.03.22.586368 — microbiology — Posted on 2024-03-23
1395 The L-lactate dehydrogenases of Pseudomonas aeruginosa are conditionally regulated but both contribute to survival during macrophage infection
Florek, L. C.; Lin, X.; Lin, Y.-C.; Chakraborty, A.; Lin, M.-H.; Price-Whelan, A.; Tong, L.; Rahme, L.; Dietrich, L. E. P.
10.1101/2024.03.21.586142 — microbiology — Posted on 2024-03-23
1396 Novel oil-associated bacteria in Arctic seawater exposed to different nutrient biostimulation regimes
Davila Aleman, F. D.; Bautista, M. A.; McCalder, J.; Jobin, K.; Murphy, S. M. C.; Else, B.; Hubert, C. R.
10.1101/2024.03.22.586348 — microbiology — Posted on 2024-03-23
1397 Laboratory evolution in Novosphingobium aromaticivorans enables rapid catabolism of a model lignin-derived aromatic dimer
Allemann, M. N.; Kato, R.; Alexander, W. G.; Giannone, R. J.; Kamimura, N.; Masai, E.; Michener, J. K.
10.1101/2024.03.22.586352 — microbiology — Posted on 2024-03-23
1398 Deciphering the RNA-binding protein network during endosomal mRNA transport
Devan, S. K.; Shanmugasundaram, S.; Muentjes, K.; Smits, S. H.; Altegoer, F.; Feldbrugge, M.
10.1101/2024.03.22.586338 — microbiology — Posted on 2024-03-23
1402 Snapshots of Pseudomonas aeruginosa SOS response activation complex reveal structural prerequisites for LexA engagement and cleavage
Vascon, F.; De Felice, S.; Gasparotto, M.; Huber, S.; Catalano, C.; Chinellato, M.; Grinzato, A.; Filippini, F.; Maso, L.; Jakobi, A. J.; Cendron, L.
10.1101/2024.03.22.585941 — biochemistry — Posted on 2024-03-23
1403 Trace Amines are Essential Metabolites for the Autocrine Regulation of β-Cell Signaling and Insulin Secretion
Keutler, K.; Hauke, S.; Laguerre, A.; Andreu-Carbo, M.; Rada, J.; Grandy, D.; Yushchenko, D. A.; Schultz, C.
10.1101/2024.03.21.585773 — biochemistry — Posted on 2024-03-23
1405 A candidate reference method for the quantification of α-synuclein in cerebrospinal fluid using an SI traceable primary calibrator and multiple reaction monitoring
Zhang, L.; Iles-Toth, E.; Cryar, A.; Drinkwater, G.; Di Vagno, L.; Pons, M.-L.; Mateyka, J.; McCullough, B.; Achtar, E.; Clarkson, C.; Goeschel, L.; Koertvelyessy, P.; Mussell, C.; Hopley, C.; Floeel, A.; Hirtz, C.; Lehmann, S.; Quaglia, M.
10.1101/2024.03.20.585804 — biochemistry — Posted on 2024-03-23
1406 Measuring X inactivation skew for retinal diseases with adaptive nanopore sequencing
Gocuk, S. A.; Lancaster, J.; Su, S.; Jolly, J. K.; Edwards, T. L.; Hickey, D. G.; Ritchie, M. E.; Blewitt, M. E.; Ayton, L. N.; Gouil, Q.
10.1101/2024.03.20.585856 — genomics — Posted on 2024-03-23
1408 Simulating animal movement trajectories from temporally dynamic step selection functions
Forrest, S. W.; Pagendam, D.; Bode, M.; Drovandi, C.; Potts, J. R.; Perry, J.; Vanderduys, E.; Hoskins, A. J.
10.1101/2024.03.19.585696 — ecology — Posted on 2024-03-23
1412 Egoviruses: distant relatives of poxviruses abundant in the gut microbiome of humans and animals worldwide
Gaia, M.; Ruscheweyh, H.-J.; Eren, A. M.; Koonin, E. V.; Sunagawa, S.; Krupovic, M.; Delmont, T. O.
10.1101/2024.03.23.586382 — microbiology — Posted on 2024-03-23
1415 Reproductive modes of polyploid Ludwigia grandiflora subsp. hexapetala in western Europe: the effects of a late-acting self-incompatibility system and its absence on genetic diversity within populations
stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.
10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-03-23
1417 Phospholipase C β4 promotes RANKL-dependent osteoclastogenesis by interacting with MKK3 and p38 MAPK
Lee, D.-K.; Jin, X.; Choi, P.-R.; Cui, Y.; Che, X.; Lee, S.; Hur, K.; Kim, H.-J.; Choi, J.-Y.
10.1101/2024.03.19.585823 — cell biology — Posted on 2024-03-23
1420 Aberrant neuronal hyperactivation causes an age- and diet-dependent decline in associative learning behavior
Aleogho, B. M.; Mohri, M.; Jang, M. S.; Tsukada, S.; Al-Hebri, Y.; Tsukada, Y.; Mori, I.; Noma, K.
10.1101/2024.03.21.586045 — neuroscience — Posted on 2024-03-23
1421 Multi-omics of a rice population identifies genes and genomic regions in rice that bestow low glycemic index and high protein content
Badoni, S.; Pasion, E.; Kor, S.; Kim, S.-R.; Misra, G.; Tiozon, R. N.; Buenafe, R. J.; Ramos-Castrosanto, A.-R.; Pratap, V.; Slamet-Loedin, I.; von Steimker, J.; Alseekh, S.; Fernie, A. R.; Kohli, A.; Khush, G.; Sreenivasulu, N.
10.1101/2024.03.21.586029 — systems biology — Posted on 2024-03-23
1423 Molecular events accompanying aggregation-induced energy quenching in Fucoxanthin-Chlorophyll Proteins
Alexandre, M. M.; Kruger, T. P.; Pascal, A. A.; Veremeienko, V.; Llansola-Portoles, M.; Gundermann, K.; van Grondelle, R.; Buechel, C.; Robert, B.
10.1101/2024.03.20.585890 — biophysics — Posted on 2024-03-23
1429 Development of a high-throughput, quantitative platform using human cerebral organoids to study virus-induced neuroinflammation in Alzheimer's disease
Olson, M. N.; Dawes, P.; Murray, L. F.; Barton, N. J.; Sundstrom, J.; Orszulak, A. R.; Chigas, S. M.; Tran, K.; Aylward, A. J.; Caliandro, M. F.; Riechers, S.-P. H.; Afshari, K.; Wang, Q.; Garber, M.; Humphries, F.; Orzalli, M. H.; Golenbock, D. T.; Heneka, M. T.; Oh, H. S.; Church, G. M.; Young-Pearse, T. L.; Knipe, D. M.; Readhead, B.; Chan, Y.; Lim, E. T.
10.1101/2024.03.21.585957 — genomics — Posted on 2024-03-23
1430 Single cell RNA sequencing of nc886, a non-coding RNA transcribed by RNA polymerase III, with a primer spike-in strategy
Shin, G.-J.; Choi, B.-H.; Eum, H. H.; Jo, A.; Kim, N.; Kang, H.; Hong, D.; Jan, J. J.; Lee, H.-H.; Lee, Y.-S.; Lee, Y. S.; Lee, H.-O.
10.1101/2024.03.20.585884 — genomics — Posted on 2024-03-23
1433 EcologicalNetworksDynamics.jl: A Julia package to simulate the temporal dynamics of complex ecological networks
Lajaaiti, I.; Bonnici, I.; Kefi, S.; Mayall, H.; Danet, A.; Beckerman, A. P.; Malpas, T.; Delmas, E.
10.1101/2024.03.20.585899 — ecology — Posted on 2024-03-23
1435 Hypothalamic Sex-Specific Metabolic Shift by Canagliflozin during Aging
Jayarathne, H. S. M.; Sullivan, R.; Stilgenbauer, L.; Debarba, L. K.; Kuchumov, A.; Koshko, L.; Scofield, S.; Liu, W.; Ginsburg, B. C.; Miller, R. A.; Sadagurski, M.
10.1101/2024.03.21.586115 — neuroscience — Posted on 2024-03-23
1436 Do you see what I see? Diffusion imaging protocol heterogeneity biases ischemic core volume, location, and clinical associations in acute stroke
Rafael-Patino, J.; Fischi-Gomez, E.; Madrona, A.; Ravano, V.; Marechal, B.; Kober, T.; Pistocchi, S.; Salerno, A.; Saliou, G.; Michel, P.; Wiest, R.; McKinley, R. I.; Richiardi, J.
10.1101/2024.03.19.585494 — neuroscience — Posted on 2024-03-23
1442 Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
Syed, F.; Ballew, O.; Lee, C.-C.; Rana, J.; Krishnan, P.; Castela, A.; Weaver, S. A.; Chalasani, N. S.; Thomaidou, S. F.; Demine, S.; Chang, G.; Coomans de Brachene, A.; Alvelos, M. I.; Marselli, L.; Orr, K.; Felton, J. L.; Liu, J.; Marchetti, P.; Zaldumbide, A.; Scheuner, D.; Eizirik, D. L.; Evans-Molina, C.
10.1101/2024.03.20.585925 — physiology — Posted on 2024-03-23
1444 Assembly Arena: Benchmarking RNA isoform reconstruction algorithms for nanopore sequencing
Sagniez, M.; Budhraja, A.; Pare, B.; Simpson, S. M.; Vinet-Ouellette, C.; Rozendaal, M.; Smith, M. A.
10.1101/2024.03.21.586080 — bioinformatics — Posted on 2024-03-23
1449 Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy
Joers, V.; Murray, B. C.; McLaughlin, C.; Oliver, D.; Staley, H.; Coronado, J. E.; Achat-Mendes, C.; Golshani, S.; Kelly, S. D.; Goodson, M.; Lee, D.; Manfredsson, F. P.; Moore, B. M.; Tansey, M. G.
10.1101/2023.08.25.554814 — immunology — Posted on 2024-03-23
1452 All eukaryotic SMC proteins induce a twist of -0.6 at each DNA-loop-extrusion step
Janissen, R.; Barth, R.; Davidson, I. F.; Taschner, M.; Gruber, S.; Peters, J.-M.; Dekker, C.
10.1101/2024.03.22.586328 — biophysics — Posted on 2024-03-23
1453 Anatomy of a pest control failure: Introgression of cytochrome P450 337B3 alleles from invasive old-world bollworm into native corn earworm.
Nufer, M. I.; Coates, B. S.; Abel, C. A.; O'Neill, P.; McKracken, M.; Jain, D.; Pierce, C. A.; Glover, J.; Towles, T.; Reddy, G. V. P.; Perera, O. P.
10.1101/2024.03.22.584691 — genetics — Posted on 2024-03-23
1457 Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues
Pearson, G. L.; Walker, E. M.; Lawlor, N.; Lietzke, A.; Sidarala, V.; Zhu, J.; Stromer, T.; Reck, E. C.; Stendahl, A. M.; Li, J.; Levi-D'Ancona, E.; Pasmooij, M. B.; Hubers, D. L.; Renberg, A.; Mohamed, K.; Parekh, V. S.; Zhang, I. X.; Thompson, B.; Zhang, D.; Ware, S. A.; Haataja, L.; Parker, S. C. J.; Arvan, P.; Yin, L.; Kaufman, B. A.; Satin, L. S.; Sussel, L.; Stitzel, M. L.; Soleimanpour, S. A.
10.1101/2022.08.02.502357 — cell biology — Posted on 2024-03-23
1459 A Large Field-of-view, Single-cell-resolution Two- and Three-Photon Microscope for Deep and Wide Imaging
Mok, A.; Wang, T.; Zhao, S.; Kolkman, K.; Wu, D.; Ouzounov, D.; Seo, C.; Wu, C.; Fetcho, J.; Xu, C.
10.1101/2023.11.14.566970 — neuroscience — Posted on 2024-03-23
1464 Genome-wide in vivo CRISPR screens identify GATOR1 as a potent tumor suppressor and its loss sensitizes MYC-driven lymphomas to mTOR inhibition
Potts, M. A.; Mizutani, S.; Deng, Y.; Vaidyanathan, S.; Ting, K.; Giner, G.; Shruti, S.; Liao, Y.; Diepstraten, S.; Kueh, A. J.; Pal, M.; Healey, G.; Tai, L.; Wang, Z.; Koenig, C.; Kaloni, D.; Whelan, L.; Milevskiy, M.; Pomilio, G.; Wei, A.; Visvader, J. E.; Papenfuss, A. T.; Wilcox, S.; Jeyasekharan, A.; Shi, W.; Lelliott, E.; Kelly, G. L.; Brown, K.; Strasser, A.; Herold, M. J.
10.1101/2022.02.16.480657 — cancer biology — Posted on 2024-03-23
1470 A zebrafish system for identifying genetic dependencies in melanocytes and melanoma
Perlee, S.; Ma, Y.; Hunter, M. V.; Swanson, J. B.; Ming, Z.; Xia, J.; Lionnet, T.; McGrail, M.; White, R.
10.1101/2024.03.22.586101 — genetics — Posted on 2024-03-23
1473 Effort Drives Saccade Selection
Koevoet, D.; Van Zantwijk, L.; Naber, M.; Mathot, S.; Van der Stigchel, S.; Strauch, C.
10.1101/2024.02.06.579052 — neuroscience — Posted on 2024-03-23
1474 Individuality across environmental context in Drosophila melanogaster
Mathejczyk, T.; Knief, C.; Haidar, M. A.; Freitag, F.; McClary, T.; Wernet, M. F.; Linneweber, G. A.
10.1101/2023.11.26.568741 — neuroscience — Posted on 2024-03-23
1475 Structure, substrate selectivity determinants and membrane interactions of a Glutamate-specific TAXI TRAP binding protein from Vibrio cholerae.
Davies, J. F.; Daab, A.; Massouh, N.; Kirkland, C.; Strongitharm, B.; Leech, A.; Farre, M.; Thomas, G. H.; Mulligan, C.
10.1101/2024.03.22.586268 — biochemistry — Posted on 2024-03-23
1476 Evidence that metastases arise de novo as new cancers from cells of target organs
Raghuram, G. V.; Pal, K.; Shende, S.; Khare, N. K.; Jadhav, V.; Shinde, S.; Prasad, R.; Wani, H.; Mittra, I.
10.1101/2023.08.09.552586 — cancer biology — Posted on 2024-03-23
1480 Optical quantification of molecular interaction strength in protein condensates
Beck, T.; van der Linden, L.-M.; Borcherds, W. M.; Kim, K.; Schluessler, R.; Mueller, P.; Franzmann, T.; Moeckel, C.; Goswami, R.; Leaver, M.; Mittag, T.; Alberti, S.; Guck, J.
10.1101/2024.03.19.585750 — biophysics — Posted on 2024-03-22
1481 In search of visual opsin of Lissachatina fulica: in silico prediction
Fedotov, D. A.; Dominova, I. N.; Zhukov, V. V.; Shirina, S.; Zikin, V.
10.1101/2024.03.19.585790 — biophysics — Posted on 2024-03-22
1483 Linking modulation of bio-molecular phase behaviour with collective interactions
Qian, D.; Ausserwoger, H.; Arter, W. E.; Scrutton, R.; Welsh, T. J.; Kartanas, T.; Ermann, N.; Qamar, S.; Fischer, C.; Sneideris, T.; St George-Hyslop, P.; Pappu, R. V.; Knowles, T.
10.1101/2023.11.02.565376 — biophysics — Posted on 2024-03-22
1484 Modulation of Biophysical Properties of Nucleocapsid Protein in the Mutant Spectrum of SARS-CoV-2
Nguyen, A.; Zhao, H.; Myagmarsuren, D.; Srinivasan, S.; Wu, D.; Chen, J.; Piszczek, G.; Schuck, P.
10.1101/2023.11.21.568093 — biophysics — Posted on 2024-03-22
1488 Multiscale computational model predicts how environmental changes and drug treatments affect microvascular remodeling in fibrotic disease
Leonard-Duke, J.; Agro, S. M. J.; Csordas, D. J.; Bruce, A. C.; Eggertsen, T. G.; Tavakol, T. N.; Barker, T. H.; Bonham, C. A.; Saucerman, J. J.; Taite, L. J.; Peirce, S. M.
10.1101/2024.03.15.585249 — bioengineering — Posted on 2024-03-22
1489 Structure, substrate selectivity determinants and membrane interactions of a Glutamate-specific TAXI TRAP binding protein rom Vibrio cholerae.
Davies, J. F.; Daab, A.; Massouh, N.; Kirkland, C.; Strongitharm, B.; Leech, A.; Farre, M.; Thomas, G. H.; Mulligan, C.
10.1101/2024.03.22.586268 — biochemistry — Posted on 2024-03-22
1490 Cohesin supercoils DNA during loop extrusion
Davidson, I. F.; Barth, R.; Horn, S.; Janissen, R.; Nagasaka, K.; Wutz, G.; Stocsits, R. R.; Bauer, B.; Dekker, C.; Peters, J.-M.
10.1101/2024.03.22.586228 — biochemistry — Posted on 2024-03-22
1492 Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach
Merten, E. M.; Sears, J. D.; Leisner, T. M.; Hardy, P. B.; Ghoshal, A.; Hossain, M. A.; Asressu, K. H.; Brown, P. J.; Stashko, M. A.; Herring, L. E.; Mordant, A. L.; Webb, T. S.; Mills, C. A.; Barker, N. K.; Arnold, J. J.; Cameron, C. E.; Streblow, D. N.; Moorman, N. J.; Heise, M.; Willson, T. M.; Popov, K. I.; Pearce, K. H.
10.1101/2024.03.22.586341 — biochemistry — Posted on 2024-03-22
1493 Discovery, Characterization and Synthetic Potential of Two Novel Bacterial Alcohol Oxidases
Cinca-Fernando, P.; Ascaso-Alegre, C.; Sevilla, E.; Martinez-Julvez, M.; Mangas-Sanchez, J.; Ferreira, P.
10.1101/2024.03.22.586125 — biochemistry — Posted on 2024-03-22
1494 The cytoplasmic tail of myelin protein zero induces morphological changes in lipid membranes
Krokengen, O. C.; Touma, C.; Mularski, A.; Sutinen, A.; Dunkel, R.; Ytterdal, M.; Raasakka, A.; Mertens, H. D. T.; Simonsen, A. C.; Kursula, P.
10.1101/2024.03.22.586069 — biochemistry — Posted on 2024-03-22
1495 VASP phase separation with priming proteins of fast endophilin mediated endocytosis modulates actin polymerization
Narayan, K. B.; James, H. P.; Cope, J.; Mondal, S.; Baeyens, L.; Milano, F.; Zheng, J.; Krause, M.; Baumgart, T.
10.1101/2024.03.21.586200 — biochemistry — Posted on 2024-03-22
1496 Single RNA molecule resolution spatial imaging of immunotherapy response in triple negative breast tumors harboring tertiary lymphoid structures
Mebane, R.; Noel, T.; Ing, N.; Gouin, K.; Shah, A.; Zitser, D.; Matinez, A.; Gupta, G. P.; Ho, A.; McArthur, H.; Shiao, S. L.; Knott, S. R. V.
10.1101/2024.03.19.585798 — genomics — Posted on 2024-03-22
1497 Probing chromatin accessibility with small molecule DNA intercalation and nanopore sequencing
Bai, G.; Dhillon, N.; Felton, C. A.; Meissner, B.; Saint-John, B.; Shelansky, R.; Meyerson, E.; Hrabeta-Robinson, E.; Hodjat, B.; Boeger, H.; Brooks, A. N.
10.1101/2024.03.20.585815 — genomics — Posted on 2024-03-22
1498 Anatomy of a pest control failure: Introgression of cytochrome P450 337B3 alleles from invasive old-world bollworm into native corn earworm.
Nufer, M. I.; Coates, B. S.; Abel, C. A.; O'Neill, P.; McKracken, M.; Jain, D.; Pierce, C. A.; Glover, J.; Towles, T.; Reddy, G. V. P.; Perera, O. P.
10.1101/2024.03.22.584691 — genetics — Posted on 2024-03-22
1499 A humanized knock-in Col6a1 mouse recapitulates a deep-intronic splice-activating variant
Bolduc, V.; Guirguis, F.; Lubben, B.; Trank, L.; Silverstein, S.; Brull, A.; Nalls, M.; Cheng, J.; Garrett, L.; Bonnemann, C. G.
10.1101/2024.03.21.581572 — genetics — Posted on 2024-03-22
1504 DNA damage drives antigen diversification through mosaic VSG formation in Trypanosoma brucei
Smith, J. E.; Wang, K. J.; Hakim, J. M.; Beaver, A. K.; Magesh, A.; Gilligan-Steinberg, S. D.; Zheng, J.; So, J.; Kennedy, E. M.; Zhang, B.; Akin, E. H.; Mwakibete, L.; Mugnier, M. R.
10.1101/2024.03.22.582209 — microbiology — Posted on 2024-03-22
1505 Predicting microbial growth conditions from amino acid composition
Barnum, T. P.; Crits-Christoph, A.; Molla, M.; Carini, P.; Lee, H. H.; Ostrov, N.
10.1101/2024.03.22.586313 — microbiology — Posted on 2024-03-22
1506 Limited potexvirus diversity in seagrasses
Lim, S. J.; Rosario, K.; Kernbach, M. E.; Gross, A. J.; Furman, B. T.; Breitbart, M.
10.1101/2023.12.11.571111 — microbiology — Posted on 2024-03-22
1508 Intercontinental dissemination and diversification of Xanthomonas perforans in tomato production
Timilsina, S.; Iruegas-Bocardo, F.; Jibrin, M. O.; Sharma, A.; Subedi, A.; Minsavage, G. V.; Huguet-Tapia, J.; Klein-Gordon, J.; Adhikari, P.; Adhikari, T. B.; Cirvilleri, G.; Belen Tapia de la Barrera, L.; Bernal, E.; Creswell, T. C.; Doan, T. T. K.; Coutinho, T. A.; Egel, D. S.; Felix-Gastelum, R.; Francis, D. M.; Kebede, M.; Lewis Ivey, M.; Louws, F. J.; Luo, L.; Maynard, E. T.; Miller, S. A.; Nguyen, N. T. T.; Osdaghi, E.; Quezado-Duval, A. M.; Roach, R.; Rotondo, F.; Ruhl, G. E.; Shutt, V. M.; Thummabenjapone, P.; Trueman, C.; Roberts, P. D.; Jones, J. B.; Vallad, G. E.; Goss, E. M.
10.1101/2024.03.22.585974 — microbiology — Posted on 2024-03-22
1510 Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species
Maeda, K.; Sumita, T.; Nishi, O.; Sushida, H.; Higashi, Y.; Nakagawa, H.; Suzuki, T.; Iwao, E.; Fanani, M. Z.; Nishiya, Y.; Iida, Y.
10.1101/2024.03.22.586281 — microbiology — Posted on 2024-03-22
1513 Higher prevalence of sacbrood virus in highbush blueberry pollination units
McAfee, A.; French, S. K.; Tsvetkov, N.; Higo, H.; Common, J.; Pernal, S. F.; Giovenazzo, P.; Hoover, S. E.; Guzman-Novoa, E.; Currie, R. W.; Veiga, P. W.; Conflitti, I. M.; Pepinelli, M.; Tran, L.; Zayed, A.; Guarna, M. M.; Foster, L. J.
10.1101/2024.03.20.585971 — zoology — Posted on 2024-03-22
1514 Functional characterization of fatty acid synthase in Hermetia illucens
Jiang, Y.; Xue, W.; Peng, Z.; Hou, P.; Kou, Z.; Chen, B.; Lu, H.; Huang, Y.
10.1101/2024.03.22.586266 — synthetic biology — Posted on 2024-03-22
1518 Both major xanthophyll cycles present in nature can provide Non-Photochemical Quenching in the model diatom Phaeodactylum tricornutum
Giossi, C. E.; Wünsch, M. A.; Dautermann, O.; Schober, A. F.; Buck, J. M.; Kroth, P. G.; Lohr, M.; Lepetit, B.
10.1101/2024.03.19.584964 — plant biology — Posted on 2024-03-22
1519 Evaluation of Octopus maya enzyme activity of the digestive gland and gastric juice
Pineda-Suazo, D.; Escobedo Hinojosa, W.; Fabian Canseco, L. E.; Gallardo, P.; Moguel Ojeda, C.; Caamal Monsreal, C.; Sanchez Arteaga, A.; Rosas, C.
10.1101/2024.03.19.585784 — physiology — Posted on 2024-03-22
1522 V1 receptive field structure contributes to neuronal response latency
Vafaei, A.; Mohammadi, M.; Khadir, A.; Zabeh, E.; YazdaniBanafsheDaragh, F.; Khorasani, M.; Lashgari, R.
10.1101/2021.12.30.474591 — neuroscience — Posted on 2024-03-22
1523 Forage conservation is a neglected source of nitrous oxide
Yang, S.; Mahmood, M.; Baral, R.; Wu, H.; Almloff, M.; Stanton, L.; Min, D.; Smiley, B.; Liams, C.; Yu, J.; Im, J.
10.1101/2024.03.19.585631 — bioengineering — Posted on 2024-03-22
1524 Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly
Buckenmeyer, M. J.; Brooks, E. A.; Taylor, M. S.; Yang, L.; Holewinski, R. J.; Meyer, T. J.; Galloux, M.; Garmendia-Cedillos, M.; Pohida, T. J.; Andresson, T.; St. Croix, B.; Wolf, M. T.
10.1101/2024.03.19.585805 — bioengineering — Posted on 2024-03-22
1527 Paradigm shift in biomarker translation: a pipeline to generate clinical grade biomarker candidates from DIA-MS discovery
Fu, Q.; Vegesna, M.; Sundararaman, N.; Damoc, E.; Arrey, T. N.; Pashkova, A.; Mengesha, E.; Debbas, P.; Joung, S.; Li, D.; Cheng, S.; Braun, J.; McGovern, D. P. B.; Murray, C.; Xuan, Y.; Van Eyk, J. E.
10.1101/2024.03.20.586018 — biochemistry — Posted on 2024-03-22
1528 A PTER-dependent pathway of taurine metabolism linked to energy balance
Wei, W.; Lyu, X.; Markhard, A. L.; Fu, S.; Mardjuki, R. E.; Cavanagh, P. E.; Zeng, X.; Rajniak, J.; Lu, N.; Xiao, S.; Zhao, M.; Dolores Moya-Garzon, M.; Truong, S. D.; Chou, C. J.; Wat, L. W.; Chidambaranathan Reghupaty, S.; Voilquin, L.; Xu, D.; Shen, F.; Huang, W.; Ramirez, C. B.; Jang, C.; Svensson, K. J.; Fischbach, M. A.; Long, J. Z.
10.1101/2024.03.21.586194 — biochemistry — Posted on 2024-03-22
1529 Deletion of arrestin-3 does not improve compulsive drug- seeking behavior in a longitudinal paradigm of oral morphine self-administration
Gooding, S.; Felth, L.; Foxall, R.; Rosa, Z.; Sall, I. J.; Gaur, A.; Ireton, K.; Gipoor, J.; King, M.; Dirks, N.; Whistler, C. A.; Whistler, J. A.
10.1101/2023.03.30.534994 — animal behavior and cognition — Posted on 2024-03-22
1531 Reconstructing the dynamics of past coral endosymbiotic algae communities using coral ancient DNA (coraDNA)
Rey, O.; Dissard, D.; Toulza, E.; Guinebert, T.; Saccas, M.; Allienne, J.-F.; Butscher, J.; Zoubir, M. B.; Iwankow, G.; Tougard, C.; Vidal-Dupiol, J.
10.1101/2024.03.21.584420 — evolutionary biology — Posted on 2024-03-22
1532 Plant species richness and the root economics space drive soil fungal communities
Hennecke, J.; Bassi, L.; Albracht, C.; Amyntas, A.; Bergmann, J.; Eisenhauer, N.; Fox, A.; Heimbold, L.; Kuyper, T.; Lange, M.; Alves de Souza, Y. P.; Rai, A.; Solbach, M. D.; Mommer, L.; Weigelt, A.
10.1101/2024.03.20.585751 — ecology — Posted on 2024-03-22
1533 Stand structure as the proximate driver of endemic biodiversity and ecosystem functions in tropical mosaic landscapes
Rajaonarimalala, R.; Korol, Y.; Andrianarimisa, A.; Dröge, S.; Fulgence, T. R.; Grass, I.; Kreft, H.; Osen, K.; Rakotomalala, A. A. N. A.; Rakouth, B.; Ranarijaona, H. L. T.; Randriamanantena, R.; Ratsoavina, F. M.; Ravaomanarivo, L. H. R.; Raveloaritiana, E.; Schwab, D.; Soazafy, M. R.; Tscharntke, T.; Wurz, A.; Hölscher, D.; Martin, D. A.
10.1101/2024.03.20.582692 — ecology — Posted on 2024-03-22
1535 Allele-specific CRISPR/Cas9 editing inactivates a single nucleotide variant associated with collagen VI muscular dystrophy
Bolduc, V.; Sizov, K.; Brull, A.; Esposito, E.; Chen, G. S.; Uapinyoying, P.; Sarathy, A.; Johnson, K.; Bonnemann, C. G.
10.1101/2024.03.22.586265 — molecular biology — Posted on 2024-03-22
1536 Mar1, an HMG-box protein, regulates n-alkane adsorption and cell morphology of the dimorphic yeast Yarrowia lipolytica
Kimura-Ishimaru, C.; Liang, S.; Matsuse, K.; Iwama, R.; Sato, K.; Watanabe, N.; Tezaki, S.; Horiuchi, H.; Fukuda, R.
10.1101/2024.03.22.586302 — microbiology — Posted on 2024-03-22
1540 High-resolution scRNA-seq reveals genomic determinants of antigen expression hierarchy in African Trypanosomes
McWilliam, K. R.; Keneskhanova, Z.; Cosentino, R. O.; Dobrynin, A.; Smith, J. E.; Subota, I.; Mugnier, M. R.; Colome-Tatche, M.; Siegel, T. N.
10.1101/2024.03.22.586247 — microbiology — Posted on 2024-03-22
1541 Neutralisation sensitivity of the SARS-CoV-2 BA.2.87.1 variant
Sheward, D. J.; Marking, U.; Bladh, O.; Held, S.; Looyens, E.; Vandenabeele, L.; Muschiol, S.; Aguilera, K.; Norin, N. G.; Oling, S.; Westerberg, M.; Martin, D.; Hedestam, G. B. K.; Albert, J.; Thalin, C.; Murrell, B.
10.1101/2024.03.21.586176 — immunology — Posted on 2024-03-22
1543 Antigen-driven CD8+ T cell clonal expansion is a prominent feature of MASH in humans and mice.
Burtis, A. E.; DeNicola, D. M.; Ferguson, M. E.; Santos, R. G.; Pinilla, C.; Kriss, M. S.; Orlicky, D. J.; Tamburini, B. A. J.; Gillen, A. E.; Burchill, M. A.
10.1101/2024.03.20.583964 — immunology — Posted on 2024-03-22
1544 Senolytic CAR T cells reverse aging-associated defects in intestinal regeneration and fitness
Eskiocak, O.; Chowdhury, S.; Shah, V.; Nnuji-John, E.; Chung, C.; Boyer, J. A.; Harris, A. S.; Habel, J.; Sadelain, M.; Beyaz, S.; Amor, C.
10.1101/2024.03.19.585779 — cell biology — Posted on 2024-03-22
1548 Adaptive Optics in an Oblique Plane Microscope
McFadden, C.; Marin, Z.; Chen, B.; Daetwyler, S.; Wang, X.; Rajendran, D.; Fiolka, R. P.
10.1101/2024.03.21.586191 — cell biology — Posted on 2024-03-22
1549 Loss of KIF13B causes time-dependent changes in ciliary polycystin-2 levels and extracellular vesicle release
Rezi, C. K.; Frei, A.; Campestre, F.; Berggreen, C. R.; Laplace, J.; Sicot, A.; Li, G.; Johansen, S. L.; Sorensen, J. K. T.; Berchtold, M. W.; Chamlali, M.; Christensen, S. T.; Boldt, K.; Anvarian, Z.; May-Simera, H. L.; Pedersen, L. B.
10.1101/2024.03.21.586066 — cell biology — Posted on 2024-03-22
1552 Space-time dynamics of genome replication studied with super-resolved microscopy
Gelleri, M.; Sterr, M.; Strickfaden, H.; Cremer, C.; Cremer, T.; Cremer, M.
10.1101/2024.03.22.586000 — cell biology — Posted on 2024-03-22
1553 Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns
Hatoyama, Y.; Islam, M.; Bond, A. G.; Hayashi, K.-I.; Ciulli, A.; Kanemaki, M. T.
10.1101/2024.03.20.586026 — cell biology — Posted on 2024-03-22
1555 A constricted mitochondrial morphology optimizes respiration.
Singh, M. K.; Cavellini, L.; Kunz, C.; Lelek, M.; Bomme, P.; Belgareh-Touze, N.; Mallet, A.; Dietrich, L.; Zimmer, C.; Cohen, M. M.
10.1101/2024.03.21.582105 — cell biology — Posted on 2024-03-22
1556 Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter
Baker, G. J.; Novikov, E.; Zhao, Z.; Vallius, T.; Davis, J. A.; Lin, J.-R.; Muhlich, J. L.; Mittendorf, E. A.; Santagata, S.; Guerriero, J. L.; Sorger, P. K.
10.1101/2023.11.01.565120 — pathology — Posted on 2024-03-22
1557 Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
Maristany, M. J.; Aguirre Gonzalez, A.; Espinosa, J. R.; Huertas, J.; Collepardo-Guevara, R.; Joseph, J. A.
10.1101/2023.06.14.543914 — biophysics — Posted on 2024-03-22
1559 Testing the mettle of METAL: A comparison of phylogenomic methods using a challenging but well-resolved phylogeny
Braun, E. L.; Oliveros, C. H.; White Carreiro, N. D.; Zhao, M.; Glenn, T. C.; Brumfield, R. T.; Braun, M. J.; Kimball, R. T.; Faircloth, B. C.
10.1101/2024.02.28.582627 — evolutionary biology — Posted on 2024-03-22
1560 DNA Double-Strand Break Movement in Heterochromatin Depends on the Histone Acetyltransferase dGcn5.
Kendek, A.; Sandron, A.; Lambooij, J.-P.; Colmenares, S. U.; Pociunaite, S. M.; Gooijers, I.; de Groot, L.; Karpen, G.; Janssen, A.
10.1101/2023.11.30.569406 — cell biology — Posted on 2024-03-22
1563 Transcriptional modulation unique to vulnerable motor neurons predict ALS across species and SOD mutations
Mei, I.; Nichterwitz, S.; Leboeuf, M.; Nijssen, J.; Lenoel, I.; Repsilber, D.; Lobsiger, C. S.; Hedlund, E.
10.1101/2024.03.15.584775 — neuroscience — Posted on 2024-03-22
1565 Eye-movement artifact correction in infant EEG
Srishyla, D.; Webb, S.; Elsabbagh, M.; O'Reilly, C.; BASIS team, Center for Brain and Cognitive Development, London,UK,
10.1101/2024.03.19.585723 — neuroscience — Posted on 2024-03-22
1566 Asymmetric Fin Shape changes Swimming Dynamics of Ancient Marine Reptiles' Soft Robophysical Models
Sprumont, H.; Allione, F.; Schwab, F.; Wang, B.; Mucingat, C.; Lunati, I.; Scheyer, T.; Ijspeert, A.; Jusufi, A.
10.1101/2024.02.15.580532 — biophysics — Posted on 2024-03-22
1567 Contrasting Sequence with Structure: Pre-training Graph Representations with PLMs
Robinson, L. C. B.; Atkinson, T.; Copoiu, L.; Bordes, P.; Pierrot, T.; Barrett, T.
10.1101/2023.12.01.569611 — bioinformatics — Posted on 2024-03-22
1568 Analyzing single-cell bisulfite sequencing data with MethSCAn
Kremer, L. P.; Braun, M.; Ovchinnikova, S.; Kuechenhoff, L.; Cerrizuela, S.; Martin-Villalba, A.; Anders, S.
10.1101/2022.06.15.496318 — bioinformatics — Posted on 2024-03-22
1571 Targeted metagenomics using probe capture detect a larger diversity of nitrogen and methane cyclinggenes in complex microbial communities than traditional metagenomics
Siljanen, H. M. P.; Manoharan, L.; Hilts, A. S.; Bagnoud, A.; Alves, R. J. E.; Jones, C. M.; Kerou, M.; Sousa, F.; Hallin, S.; Biasi, C.; Schleper, C.
10.1101/2022.11.04.515048 — microbiology — Posted on 2024-03-22
1572 Building compositional tasks with shared neural subspaces
Tafazoli, S.; Bouchacourt, F.; Ardalan, A.; Markov, N. T.; Uchimura, M.; Gomes Mattar, M. G.; Daw, N. D.; Buschman, T. J.
10.1101/2024.01.31.578263 — neuroscience — Posted on 2024-03-22
1573 Longitudinal trajectories of the neural encoding mechanisms of speech-sound features during the first year of life
Puertollano, M.; Ribas-Prats, T.; Gorina-Careta, N.; Ijjou-Kadiri, S.; Arenillas-Alcon, S.; Mondejar-Segovia, A.; Gomez-Roig, M. D.; Escera, C.
10.1101/2023.11.24.567803 — neuroscience — Posted on 2024-03-22
1575 The aging-induced long non-coding RNA MIRIAL controls endothelial cell and mitochondrial function
Kohnle, C.; Koziarek, S.; Warwick, T.; Theodorou, K.; Fischer, A.; Juni, R. P.; Muhly Reinholz, M.; Busscher, D.; Lam, F.; Vetter, F.; Wagner, J. U. G.; Sommer, J.; Gimbel, A. T.; Stanicek, L.; Guenther, S.; Wittig, I.; Maegdefessel, L.; Leisegang, M. S.; Brandes, R. P.; Dimmeler, S.; Boon, R. A.
10.1101/2024.02.28.582649 — cell biology — Posted on 2024-03-22
1576 Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis
Patel, K.; Barter, M. J.; Soul, J.; Clark, P.; Proctor, C. J.; Clark, I. M.; Young, D.; Shanley, D. P.
10.1101/2023.03.31.535081 — systems biology — Posted on 2024-03-22
1577 Meat enriched-diet and inflammation promote PI3Kα-dependent pancreatic cell plasticity that limit tissue regeneration.
Cayron, C.; Bozoglou, D.; Villard, A. V.; Reyes-Castellanos, G.; Therville, N.; Baer, R.; Arcucci, S.; Naud, N.; Tosolini, M.; Pont, F.; Ferreira Da Mota, D.; Gueraud, F.; Basset, C.; Carrier, A.; Pierre, F.; Thibault, B.; Dufresne, M.; Guillermet-Guibert, J.
10.1101/2023.08.22.554245 — pathology — Posted on 2024-03-22
1578 In vivo targeted and deterministic single cell malignant transformation
Scerbo, P.; Tisserand, B.; Delagrange, M.; Debare, H.; Bensimon, D.; Ducos, B.
10.1101/2024.01.30.577941 — cancer biology — Posted on 2024-03-22
1579 Structure-function relationships of mucociliary clearance in the human airways
Roth, D.; Sahin, A. T.; Ling, F.; Senger, C.; Quiroz, E.; Calvert, B.; van der Does, A.; Güney, T. G.; Tepho, N.; Glasl, S.; van Schadewijk, A.; von Schledorn, L.; Olmer, R.; Kanso, E.; Nawroth, J. C.; Ryan, A. L.
10.1101/2023.12.24.572054 — biophysics — Posted on 2024-03-22
1580 So ManyFolds, So Little Time: Efficient Protein Structure Prediction With pLMs and MSAs
Barrett, T. D.; Villegas-Morcillo, A.; Robinson, L.; Gaujac, B.; Admete, D.; Saquand, E.; Beguir, K.; Flajolet, A.
10.1101/2022.10.15.511553 — bioinformatics — Posted on 2024-03-22
1582 The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2
Longhurst, A. D.; Wang, K.; Suresh, H. G.; Ketavarapu, M.; Ward, H. N.; Jones, I. R.; Narayan, V.; Hundley, F. V.; Hassan, A. Z.; Boone, C.; Myers, C.; Shen, Y.; Ramani, V.; Andrews, B. J.; Toczyski, D. P.
10.1101/2024.03.18.585604 — molecular biology — Posted on 2024-03-22
1584 Extracellular vesicles produced during fungal infection in humans are immunologically active
Rezende, C. P.; Santos, P.; Piraine, R. E. A.; Silvestrini, V. C.; Barbosa, J. C.; Valera, F. C. P.; Tamashiro, E.; Podolsky, G.; Quintana, S.; Calado, R. T.; Martinez, R.; Pacheco Fill, T.; Rodrigues, M. L.; Almeida, F.
10.1101/2024.03.20.585987 — microbiology — Posted on 2024-03-22
1586 Bivalent COVID-19 vaccines boost the capacity of pre-existing SARS-CoV-2-specific memory B cells to cross-recognize Omicron subvariants
Fryer, H. A.; Geers, D.; Gommers, L.; Zaeck, L. M.; Tan, N. H.; Jones-Freeman, B.; Goorhuis, A.; Postma, D. F.; Visser, L. G.; Hogarth, P. M.; Koopmans, M. P. G.; GeurtsvanKessel, C. H.; O'Hehir, R. E.; van der Kuy, P. H. M.; de Vries, R. D.; van Zelm, M. C.
10.1101/2024.03.20.585861 — immunology — Posted on 2024-03-22
1590 GABA-ergic inhibition in human MT predicts visuo-spatial intelligence mediated by reverberation with frontal cortex
Gao, Y.; Cai, Y.-C.; Liu, D.-Y.; Yu, J.; Wang, J.; Li, M.; Xu, B.; Wang, T.; Chen, G.; Northoff, G.; Bai, R.; Song, X.
10.1101/2024.03.20.585863 — neuroscience — Posted on 2024-03-22
1593 Dual action of sphinganine in the plant disease resistance to bacteria.
Huby, E.; Villaume, S.; Chemotti, C.; Dorey, S.; Cordelier, S.; Crouzet, J.; Gilliard, G.; Terryn, C.; Berquand, A.; Herrfurth, C.; Feussner, I.; Jacquard, C.; Fontaine, F.; Clement, C.; Baillieul, F.; Deleu, M.; Dhondt-Cordelier, S.
10.1101/2024.02.07.579277 — plant biology — Posted on 2024-03-22
1594 Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing
Tetzlaff, S. K.; Reyhan, E.; Bengtson, C. P.; Schroers, J.; Wagner, J.; Schubert, M. C.; Layer, N.; Puschhof, M. C.; Faymonville, A. J.; Drewa, N.; Pramatarov, R. L.; Wissmann, N.; Alhalabi, O.; Heuer, A.; Sivapalan, N.; Campos, J.; Boztepe, B.; Scheck, J. G.; Villa, G.; Schröter, M.; Sahm, F.; Forsberg-Nilsson, K.; Breckwoldt, M. O.; Acuna, C.; Suchorska, B.; Heiland, H. D.; Saez-Rodriguez, J.; Venkataramani, V.
10.1101/2024.03.18.585565 — cancer biology — Posted on 2024-03-22
1595 How clinically relevant are prostate cancer cell lines? A comprehensive characterisation and multiomics comparison.
Ahmed, Z.; Mosabbir, W.; Tandon, D.; Pereira, S. P.; Cheema, U.; Loizidou, M.; Withington, J.; Moore, C.; Okoli, U.; Heavey, S.
10.1101/2024.03.20.585982 — cancer biology — Posted on 2024-03-22
1596 Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin
Zhang, N.; Wu, J.; Hossain, F.; Peng, H.; Li, H.; Gibson, C.; Zhang, H.; Gao, S.; Zheng, X.; Wang, Y.; Zhu, J.; Wang, J. J.; Zheng, Q.
10.1101/2024.03.20.586010 — biochemistry — Posted on 2024-03-22
1598 Interactions of netrin-1 through its glycosylation sites immobilize Deleted in Colorectal Cancer (DCC) by favoring its constitutive clustering
Uriot, K.; Blanc, O.; Auduge, N.; Faklaris, O.; Chaverot, N.; Bloch, E.; Borghi, N.; Coppey-Moisan, M.; Girard, P. P.
10.1101/2023.10.26.563740 — cell biology — Posted on 2024-03-22
1599 Atlas of Fshr Expression from Novel Reporter Mice
Chen, H.-Q.; Fang, H.; Liu, J.-T.; Chang, S.-Y.; Cheng, L.-B.; Sun, M.-X.; Feng, J.-R.; Liu, Z.; Zhang, Y.; J. Rosen, C.; Liu, P.
10.1101/2023.11.05.565707 — cell biology — Posted on 2024-03-22
1600 Septin filament assembly assists the lateral organization of membranes
El Alaoui, F.; Al-Akiki, I.; Ibanes, S.; Lyonnais, S.; Sanchez-Fuentes, D.; Desgarceaux, R.; Cazevieille, C.; Blanchard, M.-P.; PARMEGGIANI, A.; Carretero-Genevrier, A.; Piatti, S.; Picas, L.
10.1101/2024.03.19.585775 — cell biology — Posted on 2024-03-22
1602 Dynamics of brainstem arousal systems and pupil size predict cortical interactions for flexible decision-making
van den Brink, R. L.; Hagena, K.; Wilming, N.; Murphy, P. R.; Calder-Travis, J.; Finsterbusch, J.; Büchel, C.; Donner, T. H.
10.1101/2023.12.05.570327 — neuroscience — Posted on 2024-03-22
1603 Performance comparison of high throughput single-cell RNA-Seq platforms in complex tissues
Colino Sanguino, Y.; Rodriguez de la Fuente, L.; Gloss, B.; Law, A. M.; Handler, K.; Pajic, M.; Salomon, R.; Gallego Ortega, D.; Valdes Mora, F.
10.1101/2023.04.04.535585 — genomics — Posted on 2024-03-22
1604 Long non-coding RNAs direct the SWI/SNF complex to cell-specific enhancers
Oo, J. A.; Warwick, T.; Palfi, K.; McNicoll, F.; Cao, C.; Prieto-Garcia, C.; Zhou, Y.; Gavrilov, A. A.; Razin, S. V.; Lam, F.; Günther, S.; Cabrera-Orefice, A.; Wittig, I.; Pullamsetti, S. S.; Kurian, L.; Gilsbach, R.; Schulz, M. H.; Dikic, I.; Müller-McNicoll, M.; Brandes, R. P.; Leisegang, M. S.
10.1101/2024.03.21.585172 — molecular biology — Posted on 2024-03-22
1605 Exploring anterior thalamus functional connectivity with cortical regions in prospective memory with ultra-high field fMRI
Flanagan, L.; Mansur, B. d. M.; Reichert, C.; Richter, A.; Golbabaei, S.; Kizilirmak, J. M.; Sweeney-Reed, C. M.
10.1101/2024.02.14.580346 — neuroscience — Posted on 2024-03-22
1608 Wnt-Ror-Dvl signalling and the dystrophin complex organize planar-polarized membrane compartments in C. elegans muscles
Peysson, A.; Zariohi, N.; Gendrel, M.; Chambert-Loir, A.; Frebault, N.; Cheynet, E.; Andrini, O.; Boulin, T.
10.1101/2023.03.28.534519 — cell biology — Posted on 2024-03-22
1609 Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells
Yao, Y.; Lou, X.; Jin, L.; Liu, J.; Chen, Y.; Cheng, S.; Zhao, T.; Ke, S.; Zhang, L.; Xu, Y.; He, L.; Li, H.
10.1101/2023.08.03.551799 — cell biology — Posted on 2024-03-22
1611 Two structurally different oomycete lipophilic MAMPs induce distinctive plant immune responses.
Monjil, M. S.; Kato, H.; Ota, S.; Matsuda, K.; Suzuki, N.; Tenhiro, S.; Tatsumi, A.; Pring, S.; Miura, A.; Camagna, M.; Suzuki, T.; Tanaka, A.; Terauchi, R.; Sato, I.; Chiba, S.; Kawakita, K.; Ojika, M.; Takemoto, D.
10.1101/2021.10.22.465218 — plant biology — Posted on 2024-03-22
1613 Imaging genomics reveals genetic architecture of the globular human braincase
Molz, B.; Eising, E.; Alagoz, G.; Schijven, D.; Francks, C.; Gunz, P.; Fisher, S. E.
10.1101/2024.03.20.585712 — genetics — Posted on 2024-03-22
1614 The L-lactate dehydrogenases of Pseudomonas aeruginosa are conditionally regulated but both contribute to survival during macrophage infection
Florek, L. C.; Lin, X.; Lin, Y.-C.; Chakraborty, A.; Lin, M.-H.; Price-Whelan, A.; Tong, L.; Rahme, L.; Dietrich, L. E. P.
10.1101/2024.03.21.586142 — microbiology — Posted on 2024-03-22
1616 Kif7 deletion in a mouse model of human ciliopathy alters cerebral cortex development
PEDRAZA, M.; GRAMPA, V.; PUECH, J.; SCOTTO-LOMASSESE, S.; MUZERELLE, A.; MOHAMMAD, A.; RENIER, N.; METIN, C.; MASSON, J.
10.1101/2024.03.21.586159 — neuroscience — Posted on 2024-03-22
1617 Preeclamptic phenotype in transgenic mice with fetuses carrying APOL1 risk variants
Yoshida, T.; Latt, K. Z.; Shrivastav, S.; Lu, H.; Reidy, K. J.; Charlton, J. R.; Zhao, Y.; Winkler, C. A.; Reznik, S. E.; Rosenberg, A. Z.; Kopp, J. B.
10.1101/2024.03.20.586039 — molecular biology — Posted on 2024-03-21
1618 An essential and highly selective protein import pathway encoded by nucleus-forming phage
Morgan, C. J.; Enustun, E.; Armbruster, E. G.; Birkholz, E. A.; Prichard, A.; Forman, T.; Aindow, A.; Wannasrichan, W.; Peters, S.; Inlow, K.; Shepherd, I. L.; Razavilar, A.; Chaikeeratisak, V.; Adler, B. A.; Cress, B. F.; Doudna, J. A.; Pogliano, K.; Villa, E.; Corbett, K. D.; Pogliano, J.
10.1101/2024.03.21.585822 — microbiology — Posted on 2024-03-21
1620 In Vitro Efficacy of Next Generation Dihydrotriazines and Biguanides Against Babesiosis and Malaria Parasites
Vydyam, P.; Chand, M.; Gihaz, S.; Renard, I.; Heffernan, G. D.; Jacobus, L. R.; Jacobus, D. P.; Saionz, K. W.; Shah, R.; Shieh, H.-M.; Terpinski, J.; Zhao, W.; Cornillot, E.; Ben Mamoun, C.
10.1101/2024.03.20.585986 — microbiology — Posted on 2024-03-21
1621 The gases H2 and O2 in open-culture reactors influence the performance and microbiota of chain elongation into n-caproate and n-caprylate.
Spirito, C. M.; Lucas, T. N.; Patz, S.; Jeon, B. S.; Werner, J. J.; Trondsen, L. H.; Guzman, J. J.; Huson, D. H.; Angenent, L. T.
10.1101/2024.03.21.586105 — microbiology — Posted on 2024-03-21
1623 Bioinformatic prediction and high throughput in vivo screening to identify cis-regulatory elements for the development of algal synthetic promoters
Torres-Tiji, Y.; Sethuram, H.; Gupta, A.; McCauley, J.; Dutra-Molino, J.-V.; Pathania, R.; Saxton, L.; Kang, K.; Hillson, N. J.; Mayfield, S. P.
10.1101/2024.03.20.585996 — synthetic biology — Posted on 2024-03-21
1624 Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2
Wang, J.; Beyer, D.; Vaccarin, C.; He, Y.; Tanriver, M.; Benoit, R. M.; Deupi, X.; Mu, L.; Bode, J. W.; Schibli, r.; Mueller, C.
10.1101/2024.03.20.585792 — pharmacology and toxicology — Posted on 2024-03-21
1627 Delineating redox cooperativity in water-soluble and membrane multiheme cytochromes through protein design
Hardy, B. J.; Dubiel, P.; Bungay, E. L.; Rudin, M.; Williams, C.; Arthur, C. J.; Guberman-Pfeffer, M. J.; Oliveira, A. S. F.; Curnow, P.; Anderson, J. L. R.
10.1101/2024.03.21.586059 — biochemistry — Posted on 2024-03-21
1628 PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes
Singh, S.; Dransfeld, U.; Ambaw, Y.; Lopez-Scarim, J.; Farese, R. V.; Walther, T. C.
10.1101/2024.03.21.586175 — biochemistry — Posted on 2024-03-21
1630 Discovery and chemical optimisation of a Potent, Bi-cyclic (Bicycle(R)) Antimicrobial Inhibitor of Escherichia coli PBP3
Rowland, C. E.; Newman, H.; Martin, T. T.; Dods, R.; Bournakas, N.; Wagstaff, J. M.; Lewis, N.; Stanway, S. J.; Balmforth, M.; Kessler, C.; van Rietschoten, K.; Bellini, D.; Roper, D. I.; Lloyd, A. J.; Dowson, C. G.; Skynner, M. J.; Beswick, P.; Dawson, M. J.
10.1101/2024.03.20.581580 — biochemistry — Posted on 2024-03-21
1632 Redirecting the pioneering function of FOXA1 with covalent small molecules
Won, S. J.; Zhang, Y.; Reinhardt, C. J.; MacRae, N. S.; DeMeester, K. E.; Njomen, E.; Hargis, L. M.; Remsberg, J. R.; Melillo, B.; Cravatt, B. F.; Erb, M. A.
10.1101/2024.03.21.586158 — biochemistry — Posted on 2024-03-21
1634 Structural insight into bacterial co-transcriptional translation initiation
Yokoyama, T.; Murayama, Y.; Uchikubo-Kamo, T.; Tomabechi, Y.; Nagao, A.; Suzuki, T.; Shirouzu, M.; Sekine, S.-i.
10.1101/2024.03.19.585385 — biochemistry — Posted on 2024-03-21
1636 Fast clustering and cell-type annotation of scATAC data using pre-trained embeddings
LeRoy, N. J.; Smith, J. P.; Zheng, G.; Rymuza, J.; Gharavi, E.; Brown, D. E.; Zhang, A.; Sheffield, N. C.
10.1101/2023.08.01.551452 — genomics — Posted on 2024-03-21
1637 Perturbation-aware predictive modeling of RNA splicing using bidirectional transformers
McNally, C. P.; Abdulhay, N. J.; Khalaj, M.; Saberi, A.; Zaro, B. W.; Goodarzi, H.; Ramani, V.
10.1101/2024.03.20.585793 — genomics — Posted on 2024-03-21
1638 Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis
Bandyadka, S.; Lebo, D. P.; Mondragon, A.; Serizier, S. B.; Kwan, J.; Peterson, J. S.; Chasse, A. Y.; Jenkins, V.; Calikyan, A.; Ortega, A.; Campbell, J. D.; Emili, A.; McCall, K.
10.1101/2024.03.12.584558 — genetics — Posted on 2024-03-21
1639 Impact of Essential Genes on the Success of Genome Editing Experiments Generating 3,313 New Genetically Engineered Mouse Lines
Elrick, H.; Peterson, K. A.; Willis, B. J.; Lanza, D. G.; Acar, E. F.; Ryder, E. J.; Teboul, L.; Kasparek, P.; Birling, M.-C.; Adams, D. J.; Bradley, A.; Braun, R. E.; Brown, S. D.; Caulder, A.; Codner, G. F.; DeMayo, F. J.; Dickinson, M. E.; Doe, B.; Duddy, G.; Gertsenstein, M.; Goodwin, L. O.; Herault, Y.; Lintott, L. G.; Lloyd, K. C. K.; Lorenzo, I.; Mackenzie, M.; Mallon, A.-M.; McKerlie, C.; Parkinson, H.; Ramirez-Solis, R.; Seavitt, J. R.; Sedlacek, R.; Skarnes, W. C.; Wells, S.; Smedley, D.; White, J. K.; Wood, J. A.; International Mouse Phenotyping Consortium, ; Murray, S. A.; Heaney,
10.1101/2021.10.06.463037 — genetics — Posted on 2024-03-21
1640 Using human genetics to develop strategies to increase erythropoietic output from genome-edited hematopoietic stem and progenitor cells
Luna, S. E.; Camarena, J.; Hampton, J. P.; Majeti, K. R.; Charlesworth, C. T.; Soupene, E.; Jia, K.; Sheehan, V. A.; Cromer, M. K.; Porteus, M. H.
10.1101/2023.08.04.552064 — genetics — Posted on 2024-03-21
1641 Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary
Varga, G. I. B.; Maroti, Z.; Schutz, O.; Maar, K.; Nyerki, E.; Tihanyi, B.; Varadi, O.; Ginguta, A.; Kovacs, B.; Kiss, P.; Dosztig, M.; Gallina, Z.; Torok, T.; B. Szabo, J.; Makoldi, M.; Neparaczki, E.
10.1101/2024.03.20.585718 — genetics — Posted on 2024-03-21
1644 Long non-coding RNAs direct the SWI/SNF complex to cell-specific enhancers
Oo, J. A.; Warwick, T.; Palfi, K.; McNicoll, F.; Cao, C.; Prieto-Garcia, C.; Zhou, Y.; Gavrilov, A. A.; Razin, S. V.; Lam, F.; Günther, S.; Cabrera-Orefice, A.; Wittig, I.; Pullamsetti, S. S.; Kurian, L.; Gilsbach, R.; Schulz, M.; Dikic, I.; Müller-McNicoll, M.; Brandes, R. P.; Leisegang, M. S.
10.1101/2024.03.21.585172 — molecular biology — Posted on 2024-03-21
1646 Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli .
Liponska, A.; Monlezun, L.; Wilkins, I.; Ngo, S.; Oïffer, T.; Bouchachi, C.; Hunt, J. F.; Aalberts, D. P.; Boël, G.
10.1101/2024.03.21.586065 — microbiology — Posted on 2024-03-21
1648 The branched receptor binding complex of Ackermannviridae phages promotes adaptative host recognition
Sorensen, A. N.; Woudstra, C.; Kalmar, D.; Poppeliers, J.; Lavigne, R.; Sorensen, M. C. H.; Brondsted, L.
10.1101/2024.03.21.586117 — microbiology — Posted on 2024-03-21
1649 Stable, multigenerational transmission of the bean seed microbiome despite abiotic stress
Sulesky-Grieb, A.; Simonin, M.; Bintarti, A. F.; Marolleau, B.; Barret, M.; Shade, A.
10.1101/2024.03.21.586100 — microbiology — Posted on 2024-03-21
1650 The minimal SUF system can substitute for the canonical iron-sulfur cluster biosynthesis systems by using inorganic sulfide as the sulfur source.
Murata, M.; Murakami, T.; Yuda, E.; Mukai, N.; Zheng, X.; Kurachi, N.; Mori, S.; Ogawa, S.; Kunichika, K.; Fujishiro, T.; Wada, K.; Takahashi, Y.
10.1101/2024.03.20.586028 — microbiology — Posted on 2024-03-21
1651 Functional Redundancy in Candida auris Cell Surface Adhesins Crucial for Cell-Cell Interaction and Aggregation
Wang, T.; Sofras, D.; Montelongo-Jauregui, D.; Paiva, T.; Carolus, H.; Dufrene, Y.; Alfaifi, A.; McCracken, C.; Bruno, V.; Van Dijck, P.; Jabra-Rizk, M. A.
10.1101/2024.03.21.586120 — microbiology — Posted on 2024-03-21
1653 SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids
Chau, C. W.; To, A.; Au-Yeung, R. K. H.; Tang, K.; Xiang, Y.; Ruan, D.; Zhang, L.; Wong, H.; Zhang, S.; Au, M. T.; Chung, S.; Song, E.; Choi, D.-H.; Liu, P.; Yuan, S.; Wen, C.; Sugimura, R.
10.1101/2024.03.20.585837 — immunology — Posted on 2024-03-21
1654 Microbial cancer immunotherapy reprograms hematopoietic stem cells to enhance anti-tumor immunity
Daman, A. W.; Antonelli, A. C.; Redelman-Sidi, G.; Paddock, L.; Cheong, J. G.; Jurado, L. F.; Benjamin, A.; Jiang, S.; Ahimovic, D.; Khayat, S.; Bale, M. J.; Loutochin, O.; McPherson, V. A.; Pe'er, D.; Divangahi, M.; Pietzak, E.; Josefowicz, S. Z.; Glickman, M.
10.1101/2024.03.21.586166 — immunology — Posted on 2024-03-21
1655 APIR: Aggregating Universal Proteomics Database Search Algorithms for Peptide Identification with FDR Control
Chen, Y. E.; Ge, X.; Woyshner, K.; McDermott, M.; Manousopoulou, A.; Ficarro, S.; Marto, J.; Li, K.; Wang, L. D.; Li, J. J.
10.1101/2021.09.08.459494 — bioinformatics — Posted on 2024-03-21
1658 Automated In Vitro Wound Healing Assay
Cwycyshyn, J.; Stansbury, C.; Meixner, W.; Hoying, J. B.; Muir, L. A.; Rajapakse, I.
10.1101/2023.12.23.573213 — bioengineering — Posted on 2024-03-21
1665 Cell-Type Specific Reductions in Interneuron Gene Expression within Subregions of the Anterior and Posterior Cingulate Gyrus of Schizophrenia and Bipolar Disorder Subjects
Krolewski, D. M.; Waselus, M.; Bunney, B. G.; Myers, R. M.; Barchas, J. D.; Lee, F. S.; Schatzberg, A. F.; Bunney, W. E.; Akil, H.; Watson, S. J.
10.1101/2024.03.20.585908 — neuroscience — Posted on 2024-03-21
1666 Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens
Nuqui, X.; Casalino, L.; Zhou, L.; Shehata, M.; Wang, A.; Tse, A. L.; Ojha, A.; Kearns, F. L.; Rosenfeld, M. A.; Miller, E. H.; Acreman, C. M.; Ahn, S.-H.; Chandran, K.; McLellan, J. S.; Amaro, R. E.
10.1101/2023.10.24.563841 — biophysics — Posted on 2024-03-21
1667 Phase separation of polyubiquitinated proteins in UBQLN2 condensates controls substrate fate
Valentino, I. M.; Llivicota-Guaman, J. G.; Dao, T. P.; Mulvey, E. O.; Lehman, A. M.; Galagedera, S. K. K.; Mallon, E. L.; Castaneda, C. A.; Kraut, D. A.
10.1101/2024.03.15.585243 — biochemistry — Posted on 2024-03-21
1668 MU-BRAIN: MUltiethnic Brain Rna-seq for Alzheimer INitiative
Yang, Z.; Cieza, B.; Reyes-Dumeyer, D.; Lee, A.; Ma, Y.; Yilmaz, E.; Lantigua, R.; Miller, G.; Brown, L.; Honig, L.; Ciener, B.; Leskinen, S.; Sivakumar, S.; Vardarajan, B.; Dugger, B.; Jin, L.-W.; Murray, M.; Dickson, D.; Rissman, R.; Hiniker, A.; Pericak-Vance, M.; Vance, J.; Foroud, T.; Kizil, C.; Teich, A.; Mayeux, R.; Tosto, G.
10.1101/2024.02.20.581250 — genetics — Posted on 2024-03-21
1671 Ether lipids influence cancer cell fate by modulating iron uptake
Henry, W. S.; Müller, S.; Yang, J.-S.; Innes-Gold, S.; Das, S.; Reinhardt, F.; Sigmund, K.; Phadnis, V. V.; Wan, Z.; Eaton, E.; Sampaio, J. L.; Bell, G. W.; Viravalli, A.; Hammond, P. T.; Kamm, R. D.; Cohen, A. E.; Boehnke, N.; Hsu, V. W.; Levental, K. E.; Rodriguez, R.; Weinberg, R. A.
10.1101/2024.03.20.585922 — cancer biology — Posted on 2024-03-21
1672 How clinically relevant are prostate cancer cell lines? A comprehensive characterisation and multiomics comparison.
Ahmed, Z.; Mosabbir, W.; Tandon, D.; Pereira, S. P.; Cheema, U.; Loizidou, M.; Withington, J.; Moore, C.; Okoli, U.; Heavey, S.
10.1101/2024.03.20.585982 — cancer biology — Posted on 2024-03-21
1673 UDP-6-glucose dehydrogenase in hormonally responsive breast cancers
Price, M. J.; Nguyen, A. D.; Haines, C.; Baeta, C. D.; Byemerwa, J.; Mukherjee, D.; Artham, S.; Kumar, V.; Lavau, C.; Wardell, S.; Varghese, S.; Goodwin, C. R.
10.1101/2024.03.20.585919 — cancer biology — Posted on 2024-03-21
1674 BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer
Mi, W.; You, J.; Li, L.; Zhu, L.; Xia, X.; Yang, L.; Li, F.; Xu, Y.; Bi, J.; Liu, P.; Chen, L.; Li, F.
10.1101/2024.03.20.585859 — cancer biology — Posted on 2024-03-21
1675 Targeting Diffuse Midline Glioma with a novel anti-CD99 Antibody
Balakrishnan, I.; Madhavan, K.; Pierce, A. M.; Michlin, J. A.; Brunt, B.; Chetty, S. L.; Wang, D.; DeSisto, J.; Nuss, Z.; Davidson, N.; Donson, A.; Jones, K.; Mitra, S. S.; Green, A.; Dahl, N.; Vibhakar, R.; Venkataraman, S.
10.1101/2024.03.19.585814 — cancer biology — Posted on 2024-03-21
1677 CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality
Tien, J. C.-Y.; Chang, Y.; Zhang, Y.; Chou, J.; Cheng, Y.; Wang, X.; Yang, J.; Mannan, R.; Shah, P.; Wang, X.-M.; Todd, A. J.; Eyunni, S.; Cheng, C.; Rebernick, R. J.; Xiao, L.; Bao, Y.; Neiswender, J.; Brough, R.; Pettitt, S. J.; Cao, X.; Miner, S. J.; Zhou, L.; Wu, Y.-M.; Labanca, E.; Wang, Y.; Parolia, A.; Cieslik, M.; Robinson, D. R.; Wang, Z.; Feng, F. Y.; Lord, C. J.; Ding, K.; Chinnaiyan, A. M.
10.1101/2024.03.20.585990 — cancer biology — Posted on 2024-03-21
1678 Illuminating the Dark Cancer Phosphoproteome Through a Machine-Learned Co-Regulation Map of 26,280 Phosphosites
Jiang, W.; Jaehnig, E. J.; Liao, Y.; Yaron-Barir, T. M.; Johnson, J. L.; Cantley, L. C.; Zhang, B.
10.1101/2024.03.19.585786 — cancer biology — Posted on 2024-03-21
1679 Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
Wang, J.; Suh, J. M.; Woo, B. J.; Navickas, A.; Garcia, K.; Yin, K.; Fish, L.; Cavazos, T.; Hanisch, B.; Markett, D.; Yu, S.; Hirst, G.; Brown-Swigart, L.; Esserman, L. J.; van 't Veer, L. J.; Goodarzi, H.
10.1101/2024.03.19.585748 — cancer biology — Posted on 2024-03-21
1681 Neurovascular Mechanisms of Cognitive Aging: Sex-Related Differences in the Average Progression of Arteriosclerosis, White Matter Atrophy, and Cognitive Decline
Bowie, D. C.; Low, K. A.; Rubenstein, S. L.; Islam, S. S.; Zimmerman, B.; Camacho, P. B.; Sutton, B. P.; Gratton, G.; Fabiani, M.
10.1101/2023.09.06.556562 — neuroscience — Posted on 2024-03-21
1685 Investigating demic versus cultural diffusion and sex bias in the spread of Austronesian languages in Vietnam
Huong Thao, D.; Tran, H. D.; Mitsunaga, S.; Duc Duy, L.; Thanh Phuong, N.; Phuong Anh, N.; Tho Anh, N.; Minh Duc, B.; Thi Thu Hue, H.; Hai Ha, N.; Dang Ton, N.; Hubner, A.; Pakendorf, B.; Stoneking, M.; Inoue, I.; Thuy Duong, N.; Van Hai, N.
10.1101/2024.03.19.585662 — genomics — Posted on 2024-03-21
1686 Mapping single-cell developmental potential in health and disease with interpretable deep learning
Kang, M.; Armenteros, J. J. A.; Gulati, G. S.; Gleyzer, R.; Avagyan, S.; Brown, E. L.; Zhang, W.; Usmani, A.; Earland, N.; Wu, Z.; Zou, J.; Fields, R. C.; Chen, D. Y.; Chaudhuri, A. A.; Newman, A. M.
10.1101/2024.03.19.585637 — genomics — Posted on 2024-03-21
1688 Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium.
Grommisch, D.; Wang, M.; Eenjes, E.; Svetlicic, M.; Deng, Q.; Giselsson, P.; Genander, M.
10.1101/2024.01.11.575258 — cell biology — Posted on 2024-03-21
1692 Epigenetic and transcriptional consequences of chemically induced transposon mobilization in the endosperm
del Toro-de Leon, G.; van Boven, J.; Santos-Gonzalez, J.; Jiao, W.-B.; Schneeberger, K.; Köhler, C.
10.1101/2024.03.19.585643 — plant biology — Posted on 2024-03-21
1700 Simulating animal movement trajectories from temporally dynamic step selection functions
Forrest, S. W.; Pagendam, D.; Bode, M.; Drovandi, C.; Potts, J. R.; Perry, J.; Vanderduys, E.; Hoskins, A. J.
10.1101/2024.03.19.585696 — ecology — Posted on 2024-03-21
1701 Tree growth is better explained by absorptive fine roots than transport fine roots
Sanaei, A.; van der Plas, F.; Chen, H.; Davids, S.; Eckhardt, S.; Hennecke, J.; Kahl, A.; Moller, Y.; Richter, R.; Schutze, J.; Wirth, C.; Weigelt, A.
10.1101/2024.03.19.585673 — ecology — Posted on 2024-03-21
1704 The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy
POPLI, P.; Oestreich, A. K.; MAURYA, V. K.; ROWEN, M. N.; Masand, R.; Holtzman, M.; Zhang, Y.; P Lydon, J.; Shizuo Akira, P.; Moley, K.; Kommagnani, R.
10.1101/2024.03.19.585812 — developmental biology — Posted on 2024-03-21
1705 Integrin inactivation slows down neutrophils congesting the pre-metastatic lung in a model of breast cancer
Fercoq, F.; Cairns, G. S.; De Donatis, M.; Mackey, J. B.; Floerchinger, A.; McFarlane, A. J.; Raffo-Iraolagoitia, X. L.; Whyte, D.; Arnott, L. W.; Nixon, C.; Wiesheu, R.; Brown, L.; Al-Khalidi, S.; Norman, J. C.; Roberts, E. W.; Blyth, K.; Coffelt, S. B.; Carlin, L. M.
10.1101/2024.03.19.585724 — immunology — Posted on 2024-03-21
1709 Cancer-Associated Hypercalcemia Signals Through the Hindbrain to cause Anorexia
Grinman, D. Y.; Takyar, F. M.; Dann, P.; Shanabrough, M.; Brown, S.; Clemenceau, A.; Hens, J. R.; Stutz, B.; Chodosh, L. A.; Chang, W.; Schulman, G. I.; Horvath, T. L.; Wysolmerski, J. J.
10.1101/2024.03.19.585694 — cancer biology — Posted on 2024-03-21
1711 Quantitative characterization of cell niches in spatial atlases
Birk, S.; Bonafonte-Pardas, I.; Feriz, A. M.; Boxall, A.; Agirre, E.; Memi, F.; Maguza, A.; Fan, R.; Castelo-Branco, G.; Theis, F. J.; Bayraktar, O.; Talavera-Lopez, C.; Lotfollahi, M.
10.1101/2024.02.21.581428 — bioinformatics — Posted on 2024-03-21
1712 Self-Supervised Learning Reveals Clinically Relevant Histomorphological Patterns for Therapeutic Strategies in Colon Cancer
Liu, B.; Polack, M.; Coudray, N.; Quiros, A. C.; Sakellaropoulos, T.; Crobach, A. S. L. P.; van Krieken, J. H. J. M.; Yuan, K.; Tollenaar, R. A. E. M.; Mesker, W. E.; Tsirigos, A.
10.1101/2024.02.26.582106 — bioinformatics — Posted on 2024-03-21
1714 Using fanyi to reduce language barriers, promote information absorption, and communication
Wang, D.; Chen, G.; Luo, X.; Zhan, L.; Xu, S.; Wang, Q.; Li, J.; Wang, R.; Wen, S.; Yu, G.
10.1101/2023.12.21.572729 — bioinformatics — Posted on 2024-03-21
1722 The vestibulospinal nucleus is a locus of balance development
Hamling, K. R.; Harmon, K.; Kimura, Y.; Higashijima, S.-i.; Schoppik, D.
10.1101/2023.12.06.570482 — neuroscience — Posted on 2024-03-21
1725 Circadian regulation of Homologous Recombination by Cryptochrome1-mediated dampening of DNA end resection
Romero-Franco, A.; Checa-Rodriguez, C.; Jimeno, S.; Castellano-Pozo, M.; Aguilera, P.; Miras, H.; Wals, A.; Jimeno-Gonzalez, S.; Lopez-Contreras, A. J.; Huertas, P.
10.1101/2023.01.22.524239 — cell biology — Posted on 2024-03-21
1727 Separate domains of the Arabidopsis ENHANCER OF PINOID drive its own polarization and recruit PIN1 to the plasma membrane
Matthes, M.; Yun, N.; Luichtl, M.; Büschges, U.; Fiesselmann, B.; Strickland, B.; Lehnardt, M.; Torres, R.
10.1101/2024.03.11.584374 — plant biology — Posted on 2024-03-21
1734 Prdm1 Positively Regulates Liver Group 1 ILCs Cancer Immune Surveillance and Preserves Functional Heterogeneity
He, J.; Gao, L.; Wang, P.; Chan, W. K.; Zheng, Y.; Zhang, Y.; Wang, J.; Chen, H.; Yang, Z.; Wang, Y.
10.1101/2023.10.20.563222 — immunology — Posted on 2024-03-21
1735 Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling
Taylor, I. W.; Patharkar, O. R.; Hsu, C.-W.; Baer, J.; Mijar, M.; Niederhuth, C. E.; Ohler, U.; Benfey, P. N.; Walker, J. C.
10.1101/2022.07.14.500021 — plant biology — Posted on 2024-03-21
1736 A first comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas.
Gibert, M. K.; Zhang, Y.; Saha, S.; Marcinkiewicz, P.; Dube, C.; Hudson, K.; Sun, Y.; Bednarek, S.; Chagari, B.; Sarkar, A.; Roig-Laboy, C.; Neace, N.; Saoud, K.; Setiady, I.; Hanif, F.; Schiff, D.; Kumar, P.; Kefas, B.; Hafner, M.; Abounader, R.
10.1101/2023.09.12.557444 — cancer biology — Posted on 2024-03-20
1739 A yeast two-hybrid system to obtain triple-helical ligands from combinatorial random peptide libraries
Masuda, R.; Thant, K. P. P.; Kawahara, K.; Oki, H.; Kadonosono, T.; Kobayashi, Y.; Koide, T.
10.1101/2023.11.14.567114 — biochemistry — Posted on 2024-03-20
1741 The genetic architecture of recombination rates is sexually-dimorphic and polygenic in wild house sparrows (Passer domesticus).
McAuley, J. B.; Servin, B.; Burnett, H. A.; Brekke, C.; Peters, L.; Hagen, I. J.; Niskanen, A. K.; Ringsby, T. H.; Husby, A.; Jensen, H.; Johnston, S. E.
10.1101/2023.01.26.525019 — genetics — Posted on 2024-03-20
1742 Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction
Gao, X.; Guo, W.; Liu, P.; Yuwen, M.; Liu, Z.; Tan, R.; Liu, K.; Yang, Z.; Ba, J.; Bai, X.; Shama, S.; Tang, C.; Miao, K.; Pei, H.; Liu, L.; Zhu, C.; Wang, T.; Zhang, B.; Kang, J.
10.1101/2024.01.06.574490 — cell biology — Posted on 2024-03-21
1743 Interplay of IGF1R and estrogen signaling regulates hematopoietic stem and progenitor cells
Xie, Y.; Xiang, D.; Hu, X.; Pakula, H.; Park, E.-S.; Chi, J.; Linn, D. E.; Tao, L.; Li, Z.
10.1101/2024.03.20.585808 — cell biology — Posted on 2024-03-21
1744 Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy
Brody, S. L.; Pan, J.; Huang, T.; Xu, J.; Huang, H.; Koenitzer, J.; Brennan, S. K.; Nanjundappa, R.; Saba, T. G.; Berical, A.; Hawkins, F. J.; Wang, X.; Zhang, R.; Mahjoub, M. R.; Horani, A.; Dutcher, S. K.
10.1101/2024.03.20.585965 — cell biology — Posted on 2024-03-21
1748 Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain
Peach, C. J.; Tonello, R.; Gomez, K.; Calderon-Rivera, A.; Bruni, R.; Bansia, H.; Maile, L.; Manu, A.-M.; Hahn, H.; Thomsen, A. R. B.; Schmidt, B. L.; Davidson, S.; des Georges, A.; Khanna, R.; Bunnett, N. W.
10.1101/2023.12.06.570398 — neuroscience — Posted on 2024-03-20
1751 Mcam stabilizes luminal progenitor breast cancer phenotypes via Ck2 control and Src/Akt/Stat3 attenuation
Balcioglu, O.; Gates, B. L.; Freeman, D. W.; Hagos, B. M.; Mehrabad, E. M.; Ayala-Talavera, D.; Spike, B. T.
10.1101/2023.05.10.540211 — cancer biology — Posted on 2024-03-20
1756 Functional diversification of gram-negative intermembrane phospholipid transporters by intrinsic substrate preference
Rai, A. K.; Sawasato, K.; Bennett, H. C.; Kozlova, A.; Sparagna, G. C.; Bogdanov, M.; Mitchell, A. M.
10.1101/2023.06.21.545913 — microbiology — Posted on 2024-03-20
1758 Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food
Dearden, L.; Furigo, I. C.; Pantaleao, L. C.; de Almeida-Faria, J.; Kentistou, K. A.; Wong, L. W.-P.; Fernandez-Twinn, D. S.; Carreira, M. V.; Bidault, G.; Vidal-Puig, A.; Ong, K. K.; Perry, J. R.; Donato, J.; Ozanne, S. E.
10.1101/2022.06.01.494310 — neuroscience — Posted on 2024-03-20
1763 Effects of protein G-quadruplex interactions on phase transitions and protein aggregation
Sahoo, B.; Kocman, V.; Clark, N.; Myers, N.; Deng, X.; Wong, E. L.; Yang, H. J.; Kotar, A.; Guzman, B. B.; Dominguez, D. C.; Plavec, J.; Bardwell, J. C.
10.1101/2023.09.21.558871 — biochemistry — Posted on 2024-03-20
1764 Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin
Zhang, N.; Wu, J.; Hossain, F.; Peng, H.; Li, H.; Gibson, C.; Chen, M.; Zhang, H.; Gao, S.; Zheng, X.; Wang, Y.; Zhu, J.; Wang, J. J.; Maze, I.; Zheng, Q.
10.1101/2024.03.20.586010 — biochemistry — Posted on 2024-03-20
1766 Assessment of DNA quality for whole genome library preparation
Jansson, L.; Fagerholm, S. A.; Borken, E.; Gynna, A. H.; Sidstedt, M.; Forsberg, C.; Ansell, R.; Hedman, J.; Tillmar, A.
10.1101/2024.03.20.585961 — molecular biology — Posted on 2024-03-20
1767 Co-translational sorting enables a single mRNA to generate distinct polysomes with different localizations and protein fates
Salloum, S.; Seveno, M.; El-koulali, K.; Rialle, S.; George, S.; Lemmers, B.; Zibara, K.; Eliscovich, C.; Hahne, M.; Bertrand, E.
10.1101/2024.03.20.585881 — molecular biology — Posted on 2024-03-20
1770 Evidence for the key roles of the Pseudomonas syringae mobilome in shaping biotic interactions
Holtappels, D.; Rickus, G. J. E.; Morgan, T.; de Rezende, R. R.; Koskella, B.; Alfenas-Zerbini, P.
10.1101/2024.03.19.585818 — microbiology — Posted on 2024-03-20
1772 Validation of RT-qPCR primers and probes for new and old variants of SARS-CoV-2 in a world scale
Almeida, A. F. R.; Almeida, W. A.; Pereira, W. M.; Silva, R. d. S.; Venancio, L. P. R.; Fabres-Klein, M. H.; Lima, J. B.; Klein, R. C.; Araujo-Santos, T.
10.1101/2024.03.19.585194 — microbiology — Posted on 2024-03-20
1774 Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission
Tiwari, A.; Myeong, J.; Hashemiaghdam, A.; Zhang, H.; Niu, X.; Laramie, M.; Stunault, M. I.; sponagel, J.; Patti, G.; Shriver, L.; Klyachko, V.; Ashrafi, G.
10.1101/2024.03.20.586011 — neuroscience — Posted on 2024-03-20
1776 Decoding Continuous Character-based Language from Non-invasive Brain Recordings
Zhang, C.; Zheng, X.; Yin, R.; Geng, S.; Xu, J.; Gao, X.; Lv, C.; Ling, Z.; Huang, X.; Cao, M.; Feng, J.
10.1101/2024.03.19.585656 — neuroscience — Posted on 2024-03-20
1779 Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination
Wilson, E. R.; Della-Flora Nunes, G.; Shen, S.; Moore, S.; Gawron, J.; Maxwell, J.; Syed, U.; Hurley, E.; Lanka, M.; Qu, J.; Desaubry, L.; Wrabetz, L.; Poitelon, Y.; Feltri, M. L.
10.1101/2024.03.20.585915 — neuroscience — Posted on 2024-03-20
1780 Reprogramming genetic circuits using space
Alejaldre, L.; Miro-Bueno, J.; Hueso-Gil, A.; Grozinger, L.; Tas, H.; Geibler, S.; Goni-Moreno, A.
10.1101/2024.03.20.585869 — synthetic biology — Posted on 2024-03-20
1783 Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α
Delaveris, C. S.; Kong, S.; Glasgow, J.; Loudermilk, R. P.; Kirkemo, L. L.; Zhao, F.; Salangsang, F.; Phojanakong, P.; Serrano, J. A. C.; Steri, V.; Wells, J. A.
10.1101/2024.03.20.585970 — biochemistry — Posted on 2024-03-20
1787 GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density
Conery, M.; Pippin, J. A.; Wagley, Y.; Trang, K.; Pahl, M. C.; Villani, D. A.; Favazzo, L. J.; Ackert-Bicknell, C. L.; Zuscik, M. J.; Katsevich, E.; Wells, A. D.; Zemel, B. S.; Voight, B. F.; Hankenson, K. D.; Chesi, A.; Grant, S. F.
10.1101/2024.03.19.585778 — genomics — Posted on 2024-03-20
1788 Platelets induce cell apoptosis of cardiac cells via FasL after acute myocardial infarction
Krott, K. J.; Reusswig, F.; Dille, M. A.; Krueger, E.; Gorressen, S.; Karray, S.; Polzin, A.; Kelm, M.; Fischer, J. W.; Elvers, M.
10.1101/2024.03.20.585918 — molecular biology — Posted on 2024-03-20
1794 Diversity of the O-chain biosynthetic cluster in the Pelagibacterales
Haro-Moreno, J. M.; Lopez-Perez, M.; Molina-Pardines, C.; Rodriguez-Valera, F.
10.1101/2024.03.20.585866 — microbiology — Posted on 2024-03-20
1795 Gut microbiota gate host exposure to metabolites from dietary Solanums
Liou, C. S.; Iakiviak, M.; Rajniak, J.; Murugkar, P. P.; Higginbottom, S. K.; Jasper, M.; Fischbach, M. A.; Sattely, E. S.
10.1101/2024.03.20.584512 — microbiology — Posted on 2024-03-20
1796 MOB rules: Antibiotic Exposure Reprograms Metabolism to Mobilize Bacillus subtilis in Competitive Interactions
Liu, Y.; LaBonte, S. A.; Brake, C. N.; LaFayette, C.; Rosebrock, A.; Caudy, A.; Straight, P. D.
10.1101/2024.03.20.585991 — microbiology — Posted on 2024-03-20
1797 Improved genome sequence and annotation of Cutaneotrichosporon oleaginosus ATCC 20509
Nijsse, B.; Duman-Özdamar, Z. E.; Verbokkem, J. A. C.; Butler, D.; Suarez-Diez, M.; Julsing, M. K.
10.1101/2024.03.20.585711 — microbiology — Posted on 2024-03-20
1798 Antibiotics damage the colonic mucus barrier in a microbiota-independent manner
Sawaed, J.; Zelik, L.; Levin, Y.; Feeney, R.; Naama, M.; Gordon, A.; Zigdon, M.; Rubin, E.; Telpaz, S.; Modilevsky, S.; Ben-Simon, S.; Awad, A.; Harshuk-Shabso, S.; Nuriel-Ohayon, M.; Werbner, M.; Schroeder, B. O.; Erez, A.; Bel, S.
10.1101/2024.03.19.585540 — immunology — Posted on 2024-03-20
1799 Quantitating SARS-CoV-2 Neutralizing Antibodies from Human Dried Blood Spots
Berman, K.; Van Slyke, G.; Novak, H.; Rock, J.; Bievenue, R.; Damjanovic, A.; DeRosa, K.; Mirabile, G.; Giradin, R.; Dupuis, A.; McDonough, K.; Parker, M. M.; Styer, L.; MANTIS, N. J.
10.1101/2024.03.18.585599 — immunology — Posted on 2024-03-20
1801 Enhanced Working Memory Representations for Rare Events
Carrasco, C. D.; Simmons, A. M.; Kiat, J. E.; Luck, S. J.
10.1101/2024.03.20.585952 — neuroscience — Posted on 2024-03-20
1802 Cell-Type Specific Reductions in Interneuron Gene Expression within Subregions of the Anterior and Posterior Cingulate Gyrus of Schizophrenia and Bipolar Disorder Subjects
Krolewski, D. M.; Waselus, M.; Bunney, B. G.; Myers, R. M.; Barchas, J. D.; Lee, F. S.; Schatzberg, A. F.; Bunney, W. E.; Akil, H.; Watson, S. J.
10.1101/2024.03.20.585908 — neuroscience — Posted on 2024-03-20
1803 Ultrasound as a reliable guide for lumbar intrathecal injection in rats: A pilot study
Pryambodho, ; Dilogo, I. H.; Tantri, A. R.; Aman, R. A.; Senapathi, T. G. A.; Purba, J. S.; Siregar, N. C.
10.1101/2024.03.20.585888 — neuroscience — Posted on 2024-03-20
1804 Effects of context changes on memory reactivation
Ozdemir, S.; Senturk, Y. D.; Unver, N.; Demircan, C.; Olivers, C. N. L.; Egner, T.; Gunseli, E.
10.1101/2024.03.20.585920 — neuroscience — Posted on 2024-03-20
1806 Convergent effects of different anesthetics are due to changes in phase alignment of cortical oscillations
Bardon, A. G.; Ballesteros, J. J.; Brincat, S. L.; Roy, J. E.; Mahnke, M. K.; Ishizawa, Y.; Brown, E. N.; Miller, E. K.
10.1101/2024.03.20.585943 — neuroscience — Posted on 2024-03-20
1808 Variations in clustering of multielectrode local field potentials in the motor cortex of macaque monkeys during a reach-and-grasp task
Chambellant, F.; Falaki, A.; Moreau-Debord, I.; French, R.; Serrano, E.; Quessy, S.; Dancause, N.; Thomas, E.
10.1101/2024.03.20.585852 — neuroscience — Posted on 2024-03-20
1810 Deciphering the Role of Aggrecan in Parvalbumin Interneurons: Unexpected Outcomes from a Conditional ACAN Knockout That Eliminates WFA+ Perineuronal Nets
Grodem, S.; Thompson, E. H.; Roe, M. B.; Vatne, G. H.; Nymoen, I.; Buccino, A.; Madland, T.; Hafting, T.; Fyhn, M.; Lensjo, K. K.
10.1101/2024.03.20.585910 — neuroscience — Posted on 2024-03-20
1811 Sub-clinical glutamate receptor antagonist combinations prevent progressive demyelination.
Mitchener, V.; Bulman, C.; Mellor, A.; Bhatt, N.; Alghamdi, B.; Nash, J.; Morgan, D.; Proctor, R.; Smith, N.; Newman, A.; Nwabiakam, V.; Stone, G.; Woznica, W.; Harper, G.; PEREZ, A. L.; PEREZ, F.; Valentino, M.; MATUTE, C.; Fern, R.
10.1101/2024.03.19.585708 — neuroscience — Posted on 2024-03-20
1812 Circadian rhythm disruption alters mammary gland morphology and accelerates cold aggressive tumorigenesis through a LILRB4-dependent pathway
Ogunlusi, O.; Sarkar, M.; Chakrabarti, A.; Boland, D.; Nguyen, T.; Sampson, J.; Nguyen, C.; Falis, D.; Jones-Hall, Y.; Fu, L.; Mallick, B.; Keene, A.; Jones, J.; Sarkar, T. R.
10.1101/2024.03.19.585534 — cancer biology — Posted on 2024-03-20
1813 Systemic coordination of whole-body tissue remodeling in sea anemone local regeneration
Cheung, S.; Bredikhin, D.; Gerber, T.; Steenbergen, P. J.; Basu, S.; Bailleul, R.; Hansen, P.; Paix, A.; Benton, M. A.; Korswagen, H. C.; Arendt, D.; Stegle, O.; Ikmi, A.
10.1101/2024.03.20.585927 — developmental biology — Posted on 2024-03-20
1817 Eye-movement artifact correction in infant EEG
Srishyla, D.; Webb, S.; Elsabbagh, M.; O'Reilly, C.
10.1101/2024.03.19.585723 — neuroscience — Posted on 2024-03-20
1818 Otoferlin requires a free intravesicular C-terminal end for synaptic vesicle docking and fusion
Dulon, D.; Boutet de Monvel, J.; Plion, B.; Mallet, A.; Condamine, S.; Bouleau, Y.; Safieddine, S.
10.1101/2024.03.20.585901 — neuroscience — Posted on 2024-03-20
1820 Parallel Encoding of Speech in Human Frontal and Temporal Lobes
Hullett, P. W.; Leonard, M. K.; Gorno-Tempini, M. L. W.; Mandelli, M. L.; Chang, E. F.
10.1101/2024.03.19.585648 — neuroscience — Posted on 2024-03-20
1821 Inverse and Postponed Impacts of Extracellular Tau PHF on Astrocytes and Neurons' Mitochondrial Function
Zufferey, V.; Parietti, E.; Barve, A.; Espourteille, J.; Varisco, Y.; Fabbri, K.; Capotosti, F.; Preitner, N.; Richetin, K.
10.1101/2024.03.19.585791 — neuroscience — Posted on 2024-03-20
1822 Gamma-TuRC proteins contribute to the dynamic organization of MTOCs during Drosophila spermatogenesis
Alzyoud, E.; Nemeth, D.; Vedelek, V.; Szögi, T.; Krecsmarik, M.; Lipinszki, Z.; Sinka, R.
10.1101/2024.03.20.585862 — cell biology — Posted on 2024-03-20
1823 BRD8 guards the pluripotent state by sensing and maintaining histone acetylation
Sun, L.; Fu, X.; Xiao, Z.; Ma, G.; Zhou, Y.; Hu, H.; Shi, L.; Li, D.; Jauch, R.; Hutchins, A.
10.1101/2024.03.20.585857 — cell biology — Posted on 2024-03-20
1824 Estrogen regulation and functional role of FGFR4 in estrogen receptor positive breast cancer
Ding, K.; Chen, L.; Levine, K. M.; Sikora, M. J.; Tasdemir, N.; Dabbs, D.; Jankowitz, R.; Hazan, R. S.; Shah, O. S.; Xavier, J. M.; LEE, A. V.; Oesterreich, S.
10.1101/2024.03.18.585626 — cancer biology — Posted on 2024-03-20
1825 Epigenetic landscape reorganization and reactivation of embryonic development genes are associated with malignancy in IDH-mutant astrocytoma
Ghisai, S. A.; van Hijfte, L.; Vallentgoed, W. R.; Tesileanu, C. M. S.; de Heer, I.; Kros, J. M.; Sanson, M.; Gorlia, T.; Wick, W.; Vogelbaum, M. A.; Brandes, A. A.; Franceschi, E.; Clement, P. M.; Nowak, A. K.; Golfinopoulos, V.; van den Bent, M. J.; French, P. J.; Hoogstrate, Y.
10.1101/2024.03.19.585212 — cancer biology — Posted on 2024-03-20
1829 Structural and genetic diversity in the secreted mucins, MUC5AC and MUC5B
Plender, E. G.; Prodanov, T.; Hsieh, P.; Nizamis, E.; Harvey, W. T.; Sulovari, A.; Munson, K. M.; Kaufman, E.; O'Neal, W. K.; Valdmanis, P. N.; Marschall, T.; Eichler, E. E.
10.1101/2024.03.18.585560 — genomics — Posted on 2024-03-20
1830 Advanced median-based genetic similarity analysis in Kazakh Tazy dogs: A novel approach for breed conformity assessment
Perfilyeva, A.; Mussabayev, R.; Bespalova, K.; Kuzovleva, Y.; Bespalov, S.; Begmanova, M.; Amirgalyeva, A.; Vishnyakova, O.; Nazarenko, I.; Perfilyeva, Y.; Plakhov, K.; Djansugurova, L.
10.1101/2024.03.19.585659 — genomics — Posted on 2024-03-20
1832 Ibudilast Protects Retinal Bipolar Cells from Excitotoxic Retinal Damage and Activates the mTOR Pathway
Hamadmad, S.; Taylor, T. H.; Goswami, S.; Hawthorn, E.; Chaurasia, S.; Martini, D.; Summitt, D.; Zaatari, A.; Urbanski, E. G.; Bernstein, K.; Racine, J.; Satoskar, A.; El-Hodiri, H. M.; Fischer, A. J.; Cebulla, C. M.
10.1101/2024.03.18.585556 — neuroscience — Posted on 2024-03-20
1833 Development of a novel, non-invasive and whole brain biomarker of demyelination in a mouse model of multiple sclerosis
Beliard, B.; Delay, L.; Rivals, I.; Travert-Jouanneau, Y.; Ialy-Radio, N.; Le-Goazigo, A. R.; Deffieux, T.; Bradley, D. P.; Tanter, M.; Pezet, S.
10.1101/2024.03.18.585596 — neuroscience — Posted on 2024-03-20
1835 Ventral hippocampus mediates inter-trial responding in signaled active avoidance
Oleksiak, C. R.; Plas, S. L.; Carriaga, D. A.; Vasudevan, K.; Maren, S.; Moscarello, J. M.
10.1101/2024.03.18.585627 — neuroscience — Posted on 2024-03-20
1837 Incretin hormones and pharmacomimetics rapidly inhibit AgRP neuron activity to suppress appetite
McMorrow, H. E.; Lorch, C. M.; Hayes, N. W.; Fleps, S. W.; Frydman, J. A.; Xia, J. L.; Samms, R. J.; Beutler, L. R.
10.1101/2024.03.18.585583 — neuroscience — Posted on 2024-03-20
1838 Rapamycin Treatment Reduces Brain Pericyte Constriction in Ischemic Stroke
Beard, D.; Brown, L. S.; Morris, G. P.; Couch, Y.; Adriaanse, B. A.; Simoglou Karali, C.; Schneider, A. M.; Howells, D. W.; Redzic, Z. B.; Sutherland, B. A.; Buchan, A. M.
10.1101/2024.03.18.584333 — neuroscience — Posted on 2024-03-20
1844 Molecular Phylogeny and Cryptic Morphology: A Combined Approach to Taxonomic Novelties in Polycarpaea (Caryophyllaceae) from Vietnam
Tran, T. V.; Hoang, T. T.; Le, L. B.; Le, N. T. K.; Nguyen, M. T. A.; Truong, A. T. L.; Tran, N. T.; Tran, V. T.; Le, S. V.; Duong, K. T.; Hoang, K. V. B.; Le, T. N.; Nguyen, B. V.
10.1101/2024.03.18.585622 — plant biology — Posted on 2024-03-20
1847 Anion exchange regulates intestinal mucus expansion while Cftr regulates de novo mucus secretion
Ljungholm, P. L.; Ermund, A.; Garsveden, M. M. S.; Pettersson, V. L.; Gustafsson, J. K.
10.1101/2024.03.18.585614 — physiology — Posted on 2024-03-20
1849 Pro-cognitive Effects of Dual Tacrine Derivatives Acting as Cholinesterase Inhibitors and NMDA Receptor Antagonists
Chvojkova, M.; Kolar, D.; Kovacova, K.; Cejkova, L.; Misiachna, A.; Hakenova, K.; Gorecki, L.; Horak, M.; Korabecny, J.; Soukup, O.; Vales, K.
10.1101/2024.03.18.585591 — pharmacology and toxicology — Posted on 2024-03-20
1850 Comparative transcriptome of normal and cancer- associated fibroblasts
Abikar, A.; Subhani, M. M. M.; Athalye, R. R.; Nadig, N.; Tamboli, N.; Babu, V.; Ramaiah, K.; Ranganathan, P.
10.1101/2024.03.18.585496 — cancer biology — Posted on 2024-03-20
1851 A molecularly engineered lectin destroys EGFR and inhibits the growth of non-small cell lung cancer
Chan, S. M.; Raglow, Z.; Pal, A.; Gitlin, S. D.; Legendre, M.; Thomas, D.; Mehta, R. K.; Tan, M.; Nyati, M. K.; Rehemtulla, A.; Markovitz, D.
10.1101/2024.03.18.585535 — cancer biology — Posted on 2024-03-20
1852 Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch
Gretarsson, K. H.; Abini-Agbomson, S.; Gloor, S.; Weinberg, D. N.; McCuiston, J. L.; Kumary, V. U. N. S.; Hickman, A.; Sahu, V.; Lee, R.; Xu, X.; Lipieta, N.; Flashner, S.; Adeleke, O. A.; Popova, I. K.; Taylor, H.; Noll, K.; Windham, C. L.; Maryanski, D.; Venters, B. J.; Nakagawa, H.; Keogh, M.; Armache, K.-J.; Lu, C.
10.1101/2024.03.18.585588 — cancer biology — Posted on 2024-03-20
1853 Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer
Lee, E.; Zhang, Z.; Chen, C.-C.; Choi, D.; Rivera, A. C. A.; Linton, E.; Ho, Y.-j.; Love, J.; LaClair, J.; Wongvipat, J.; Sawyers, C.
10.1101/2024.03.18.585532 — cancer biology — Posted on 2024-03-20
1854 Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer
Launonen, I.-M. P.; Erkan, E. P.; Niemiec, I.; Junquera, A.; Hincapie-Otero, M.; Afenteva, D.; Liang, Z.; Salko, M.; Szabo, A.; Perez-Villatoro, F.; Falco, M. M.; Li, Y.; Micoli, G.; Nagaraj, A.; Haltia, U.-M.; Kahelin, E.; Oikkonen, J.; Hynninen, J.; Virtanen, A.; Nirmal, A. J.; Vallius, T.; Hautaniemi, S.; Sorger, P. K.; Vaharautio, A.; Farkkila, A.
10.1101/2024.03.19.585657 — cancer biology — Posted on 2024-03-20
1855 Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer
Cheng, C.; Hu, J.; Mannan, R.; Bhattacharyya, R.; Rossiter, N. J.; Magnuson, B.; Wisniewski, J. P.; Zheng, Y.; Xiao, L.; Li, C.; Awad, D.; He, T.; Bao, Y.; Zhang, Y.; Cao, X.; Wang, Z.; Mehra, R.; Morlacchi, P.; Sahai, V.; Pasca di Magliano, M.; Shah, Y. M.; Ding, K.; Qiao, Y.; Lyssiotis, C. A.; Chinnaiyan, A. M.
10.1101/2024.03.18.585580 — cancer biology — Posted on 2024-03-20
1857 A Novel Tool for Multi-Omics Network Integration and Visualization: A Study of Glioma Heterogeneity
Coletti, R.; Carrilho, J.; Martins, E. P.; Goncalves, C. S.; Costa, B. M.; Lopes, M. B.
10.1101/2024.03.18.585500 — bioinformatics — Posted on 2024-03-20
1864 Cyborg islets: implanted flexible electronics reveal principles of human islet electrical maturation
Li, Q.; Liu, R.; Lin, Z.; Zhang, X.; Silva, I. G.; Pollock, S. D.; Alvarez-Dominguez, J. R.; Liu, J.
10.1101/2024.03.18.585551 — bioengineering — Posted on 2024-03-20
1866 A unique and biocompatible approach for corneal collagen crosslinking in vivo
GULZAR, A.; KALELI, H. N.; Koseoglu, G. D.; Hasanreisoglu, M.; Yildiz, A.; Sahin, A.; KIZILEL, S.
10.1101/2024.03.18.585574 — bioengineering — Posted on 2024-03-20
1868 Light-gated Integrator for Highlighting Kinase Activity in Living Cells
Lin, W.; Phatarphekar, A.; Zhong, Y.; Liu, L.; Kwon, H.-B.; Gerwick, W. H.; Wang, Y.; Mehta, S.; Zhang, J.
10.1101/2024.03.18.585554 — bioengineering — Posted on 2024-03-20
1869 Asymmetric triangular body-cover model of the vocal folds with bilateral intrinsic muscle activation
Pena, J. A. P.; Calvache, C.; Alzamendi, G. A.; Ibarra, E.; Solaque, L.; Peterson, S. D.; Zanartu, M.
10.1101/2024.03.18.585590 — bioengineering — Posted on 2024-03-20
1870 Generation of human-pig chimeric renal organoids using iPSC technology
Fujimori, K.; Yamanaka, S.; Shimada, K.; Matsui, K.; Kawagoe, S.; Kuroda, T.; Ikeda, A.; Inoue, M.; Kobayashi, E.; Yokoo, T.
10.1101/2024.03.19.584036 — bioengineering — Posted on 2024-03-20
1872 Intricate interactions between antiviral immunity and transposable element control in Drosophila
Mayeux, C. A.; Larue, A.; Oliveira, D. S.; Varoqui, M.; Henri, H.; Rebollo, R.; Kremer, N.; Chambeyron, S.; Fablet, M.
10.1101/2024.03.18.585529 — evolutionary biology — Posted on 2024-03-20
1873 Presence of Triatoma breyeri (Reduviidae, Triatominae) in Bolivia
Lardeux, F.; Llanos, A.; Rodriguez, R.; Abate, L.; Bousses, P.; Tejerina-Lardeux, R.; Barnabe, C.; Garcia, L.
10.1101/2024.03.18.585491 — ecology — Posted on 2024-03-20
1874 Pollination services to crops of watermelon (Citrullus lanatus) and green tomato (Physalis ixocarpa) in the coastal region of Jalisco, Mexico
Delgado-Carrillo, O.; Marten-Rodriguez, S.; Ramirez-Mejia, D.; Novais, S.; Quevedo, A.; Ghilardi, A.; Sayago, R.; Lopezaraiza-Mikel, M.; Perez-Trujillo, E.; Quesada, M.
10.1101/2024.03.18.585619 — ecology — Posted on 2024-03-20
1876 NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals
Mougios, N.; Cotroneo, E. R.; Imse, N.; Setzke, J.; Rizzoli, S.; Simeth, N. A.; Tsukanov, R.; Opazo, F.
10.1101/2024.03.18.585511 — neuroscience — Posted on 2024-03-20
1880 Cross-transmission of resistant gastrointestinal nematodes between wildlife and transhumant sheep
Beaumelle, C.; Toigo, C.; Papet, R.; Benabed, S.; Beurier, M.; Bordes, L.; Brignone, A.; Curt-Grand-Gaudin, N.; Garel, M.; Ginot, J.; Jacquiet, P.; Miquel, C.; Poirel, M.-T.; Serafino, A.; Vannard, E.; Bourgoin, G.; Yannic, G.
10.1101/2023.07.21.550073 — ecology — Posted on 2024-03-20
1881 Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase
Schmerling, C.; Schroeder, C.; Zhou, X.; Busche, T.; Kalinowski, J.; Montero, L.; Schmitz, O.; Kaschani, F.; Ninck, S.; Kaiser, M.; Bost, J.; Wassmer, B.; Albers, S.-V.; Siebers, B.; Braesen, C.
10.1101/2024.02.29.582781 — microbiology — Posted on 2024-03-20
1882 Involvement of ArlI, ArlJ, and CirA in Archaeal Type-IV Pilin-Mediated Motility Regulation
Chatterjee, P.; Garcia, M.; Cote, J.; Yun, K.; Legerme, G.; Habib, R.; Tripepi, M.; Young, C.; Kulp, D. W.; Dyall-Smith, M.; Pohlschroder, M.
10.1101/2024.03.04.583388 — microbiology — Posted on 2024-03-20
1887 Perilipin membrane-integration determines Lipid Droplet heterogeneity in differentiating adipocytes
Majchrzak, M.; Stojanovic, O.; Ajjaji, D.; Ben M'barek, K.; Omrane, M.; THIAM, A. R.; Klemm, R. W.
10.1101/2023.10.30.564726 — cell biology — Posted on 2024-03-20
1888 WITHDRAWN: The cardiac lncRNA Chantico directly regulates Cxcl1 chemokine transcription
Hall, J. M.; Kainth, A. S.; Rowton, M. J.; Lu, E.; Haddad, G.; Keplinger, A. J.; Scepanovic, J.; Perez-Cervantes, C.; Chan, S. S. K.; Piccirilli, J. A.; Moskowitz, I. P.; Ruthenburg, A. J.
10.1101/2021.12.23.474040 — molecular biology — Posted on 2024-03-20
1890 Sex classification from functional brain connectivity: Generalization to multiple datasets
Wiersch, L.; Friedrich, P.; Hamdan, S.; Komeyer, V.; Hoffstaedter, F.; Patil, K. R.; Eickhoff, S. B.; Weis, S.
10.1101/2023.08.30.555495 — neuroscience — Posted on 2024-03-20
1895 SIRV: Spatial inference of RNA velocity at the single-cell resolution
Abdelaal, T.; Grossouw, L.; Pasterkamp, R. J.; Lelieveldt, B. P. F.; Reinders, M. J. T.; Mahfouz, A.
10.1101/2021.07.26.453774 — bioinformatics — Posted on 2024-03-20
1896 Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton
Yamamoto, T.; Ishibashi, T.; Mimori-Kiyosue, Y.; Hiver, S.; Tokushige, N.; Tarama, M.; Takeichi, M.; Shibata, T.
10.1101/2023.08.16.553476 — cell biology — Posted on 2024-03-20
1897 Identification of a Rabenosyn-5 like protein and Rab5b in host cell cytosol uptake reveals conservation of endosomal transport in malaria parasites
Sabitzki, R.; Rossmann, A.-L.; Schmitt, M.; Flemming, S.; Guillen-Samander, A.; Behrens, H. M.; Jonscher, E.; Hoehn, K.; Froehlke, U.; Spielmann, T.
10.1101/2023.04.05.535711 — microbiology — Posted on 2024-03-20
1898 Unravelling the neural dynamics of hypnotic susceptibility: Aperiodic neural activity as a central feature of hypnosis
Landry, M.; da Silva Castanheira, J.; Boisvert, C.; Rousseaux, F.; Sackur, J.; Raz, A.; Ogez, D.; Rainville, P.; Jerbi, K.
10.1101/2023.11.16.567097 — neuroscience — Posted on 2024-03-20
1899 Deletion of FNDC5/Irisin modifies murine osteocyte function in a sex-specific manner
Shimonty, A.; Pin, F.; Prideaux, M.; Peng, G.; Huot, J.; Kim, H.; Rosen, C. j.; Spiegelman, B. M.; Bonewald, L. F.
10.1101/2023.11.06.565774 — physiology — Posted on 2024-03-20
1901 Calcineurin promotes adaptation to chronic stress through two distinct mechanisms
Flynn, M. J.; Harper, N. W.; Li, R.; Zhu, L. J.; Lee, M. J.; Benanti, J. A.
10.1101/2024.03.19.585797 — cell biology — Posted on 2024-03-20
1902 The intracellular Ca2+ sensitivity of transmitter release from neocortical boutons
Bornschein, G.; Brachtendorf, S.; Eshra, A.; Kraft, R.; Eilers, J.; Hallermann, S.; Schmidt, H.
10.1101/2024.02.26.582057 — neuroscience — Posted on 2024-03-20
1908 Shedding light on blue-green photosynthesis: A wavelength-dependent mathematical model of photosynthesis in Synechocystis sp. PCC 6803
Pfennig, T.; Kullmann, E.; Zavrel, T.; Nakielski, A.; Ebenhöh, O.; Cerveny, J.; Bernat, G.; Matuszynska, A. B.
10.1101/2023.06.30.547186 — plant biology — Posted on 2024-03-20
1910 Functional omics of ORP7 in primary endothelial cells.
Taskinen, J. H.; Holopainen, M.; Ruhanen, H.; Kakela, R.; Olkkonen, V. M.
10.1101/2024.03.19.585674 — molecular biology — Posted on 2024-03-20
1916 Synapse specific and plasticity-regulated AMPAR mobility tunes synaptic integration
Nowacka, A.; Getz, A. M.; Zieger, H.; Bessa-Neto, D.; Breillat, C.; Daburon, S.; Lemoigne, C.; Marais, S.; Ducros, M.; Penn, A. C.; Sainlos, M.; Choquet, D.
10.1101/2024.03.19.584837 — neuroscience — Posted on 2024-03-20
1920 One gene - two proteins: The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration.
Petragnano, F.; Fasciani, I.; Wang, Z.; Edwards, R.; Telugu, N.; Pietrantoni, I.; Zabel, U.; Zauber, H.; Grieben, M.; Terzenidou, M. E.; Di Gregorio, J.; Pellegrini, C.; Santini, S.; Taddei, A. R.; Poehl, B.; Aringhieri, S.; Carli, M.; Aloisi, G.; Marampon, F.; Charlesworth, E.; Roman, A.; Diecke, S.; Flati, V.; Giorgi, F.; Scarselli, M.; Tobin, A. B.; Amicarelli, F.; Tokatlidis, K.; Rossi, M.; Lohse, M. J.; Annibale, P.; Maggio, R.
10.1101/2021.04.13.438299 — cell biology — Posted on 2024-03-19
1921 Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction
Gao, X.; Yuwen, M.; Guo, W.; Liu, P.; Liu, Z.; Tan, R.; Liu, K.; Yang, Z.; Ba, J.; Bai, X.; Shama, S.; Tang, C.; Liu, L.; Zhu, C.; Wang, T.; Zhang, B.; Kang, J.
10.1101/2024.01.06.574490 — cell biology — Posted on 2024-03-19
1922 Fyn-mediated phosphorylation of Menin disrupts telomere maintenance in stem cells
Paul, S.; McCourt, P. M.; Le, L. T. M.; Ryu, J.; Czaja, W.; Bode, A. M.; Contreras-Galindo, R.; Dong, Z.
10.1101/2023.10.04.560876 — molecular biology — Posted on 2024-03-19
1923 A packaging signal-binding protein regulates the assembly checkpoint of integrative filamentous phages
Yeh, T.-Y.; Feehley, M. C.; Feehley, P. J.; Ooi, V. Y.; Hung, Y.-Y.; Wang, S.-C.; Contreras, G. P.
10.1101/2024.03.19.585677 — microbiology — Posted on 2024-03-19
1925 Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
Yulo, P. R.; Desprat, N.; Gerth, M. L.; Ritzl-Rinkenberger, B.; Farr, A. D.; Liu, Y.; Zhang, X.-X.; Miller, M.; Cava, F.; Rainey, P. B.; Hendrickson, H. L.
10.1101/263681 — microbiology — Posted on 2024-03-19
1926 Spyglass: a framework for reproducible and shareable neuroscience research
Lee, K. H.; Denovellis, E. L.; Ly, R.; Magland, J.; Soules, J.; Comrie, A. E.; Gramling, D. P.; Guidera, J. A.; Nevers, R.; Adenekan, P.; Brozdowski, C.; Bray, S. R.; Monroe, E.; Bak, J. H.; Coulter, M.; Sun, X.; Broyles, E.; Shin, D.; Chiang, S.; Holobetz, C.; Tritt, A.; Ruebel, O.; Nguyen, T.; Yatsenko, D.; Chu, J.; Kemere, C.; Garcia, S.; Buccino, A.; Frank, L. M.
10.1101/2024.01.25.577295 — neuroscience — Posted on 2024-03-19
1928 Reconstructing Voice Identity from Noninvasive Auditory Cortex Recordings
Lamothe, C.; Thoret, E.; Trapeau, R.; Giordano, B. L.; Sein, J.; Takerkart, S.; Ayache, S.; Artieres, T.; Belin, P.
10.1101/2024.02.27.582302 — neuroscience — Posted on 2024-03-19
1929 Spiking GABAergic OPC tumor cells prolong survival in IDH1 mutant glioma
Curry, R. N.; Ma, Q.; McDonald, M. F.; Ko, Y.; Srivastava, S.; Chin, P.-S.; He, P.; Lozzi, B.; Jing, J.; Athukuri, P.; Wang, S.; Harmanci, A. O.; Arenkiel, B.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2024.03.02.583026 — cancer biology — Posted on 2024-03-19
1932 Multi-ContrastiveVAE disentangles perturbation effects in single cell images from optical pooled screens
Wang, Z. J.; Lopez, R.; Huetter, J.-C.; Kudo, T.; Yao, H.; Hanslovsky, P.; Hoeckendorf, B.; Moran, R.; Richmond, D.; Regev, A.
10.1101/2023.11.28.569094 — bioinformatics — Posted on 2024-03-19
1933 Reference Sequence Browser: An R application with a User-Friendly GUI to rapidly query sequence databases
Rapp, S. L.; Tapias Gomez, J.; Ramesh, S.; Levine, B.; Tapias-Gomez, D.; Chung, D.; Truong, Z.
10.1101/2023.09.20.558722 — bioinformatics — Posted on 2024-03-19
1936 Senescent cells inhibit muscle differentiation via the SASP-lipid 15d-PGJ2 mediated modification and control of HRas
Pundlik, S. S.; Barik, A.; Venkatesvaran, A.; Sahoo, S. S.; Jaysingh, M. A.; Math, R. G. H.; Ramanathan, A.
10.1101/2023.12.23.573200 — biochemistry — Posted on 2024-03-19
1937 Hidden evolutionary constraints dictate the retention of coronavirus accessory genes
Goldstein, S. A.; Feeley, T. M.; Babler, K. M.; Hilbert, Z. A.; Downhour, D. M.; Moshiri, N.; Elde, N. C.
10.1101/2023.10.12.561935 — evolutionary biology — Posted on 2024-03-19
1942 Functional omics of ORP7 in primary endothelial cells.
Taskinen, J. H.; Holopainen, M.; Ruhanen, H.; Kakela, R.; Olkkonen, V. M.
10.1101/2024.03.19.585674 — molecular biology — Posted on 2024-03-19
1943 Model-driven engineering of Cutaneotrichosporon oleaginosus ATCC 20509 for improved microbial oil production
Duman-Özdamar, Z. E.; Julsing, M. K.; Verbokkem, J. A. C.; Wolbert, E.; Martins dos Santos, V. A. P.; Hugenholtz, J.; Suarez-Diez, M.
10.1101/2024.03.19.585731 — molecular biology — Posted on 2024-03-19
1944 Regulation of Diseases-Associated Microglia in the Optic Nerve by Lipoxin B4 and Ocular Hypertension
Maurya, S.; Lin, M.; Karnam, S.; Singh, T.; Kumar, M.; Ward, E. L.; Flanagan, J.; Gronert, K.
10.1101/2024.03.18.585452 — molecular biology — Posted on 2024-03-19
1946 Enrichment of allelic editing outcomes by Prime Editing in iPS cells
Niwa, R.; Matsumoto, T.; Liu, A. Y.; Kawato, M.; Kondo, T.; Tsukita, K.; Inoue, H.; Maurissen, T. L.; Woltjen, K.
10.1101/2024.03.19.585665 — bioengineering — Posted on 2024-03-19
1950 Comparative venom analysis between melanistic and normally-colored phenotypes of the common adder (Vipera berus)
Schulte, L.; Uhrig, L.; Eichberg, J.; Schwartze, M.; Auth, I.; Schulz, M.; Lindner, T.; Hien, P.; Hardes, K.; Vilcinskas, A.; Lueddecke, T.
10.1101/2024.03.18.585504 — molecular biology — Posted on 2024-03-19
1951 HOCl-producing Electrochemical Bandage is Active in Murine Polymicrobial Wound Infection
Fleming, D.; Bozyel, I.; Koscianski, C. A.; Ozdemir, D.; Karau, M. J.; Cuello, L.; Anoy, M. M. I.; Gelston, S.; Schuetz, A. N.; Greenwood-Quaintance, K. E.; Mandrekar, J. N.; Beyenal, H.; Patel, R.
10.1101/2024.03.19.585100 — microbiology — Posted on 2024-03-19
1953 Medication Use is Associated with Distinct Microbial Features in Anxiety and Depression
Dilmore, A. H.; Kuplicki, R.; McDonald, D.; Kumar, M.; Estaki, M.; Youngblut, N. D.; Tyakht, A.; Ackermann, G.; Blach, C.; MahmoudianDehkordi, S.; Dunlop, B.; Bhattacharyya, S.; Guinjoan, S.; Mandaviya, P.; Ley, R.; Kaddurah-Daouk, R.; Paulus, M. P.; Knight, R.; Alzheimer Gut Microbiome Project Consortium,
10.1101/2024.03.19.585820 — microbiology — Posted on 2024-03-19
1956 14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation
Rial, S. A.; You, Z.; Vivoli, A.; Sean, D.; Alkhoury, A.; Lavoie, G.; Civelek, M.; Martinez-sanchez, A.; Roux, P. P.; Durcan, T.; Lim, G.
10.1101/2024.03.18.585495 — physiology — Posted on 2024-03-19
1957 Molecular basis of mRNA delivery to the bacterial ribosome
Webster, M. W.; Chauvier, A.; Rahil, H.; Graziadei, A.; Charles, K.; Takacs, M.; Saint-Andre, C.; Rappsilber, J.; Walter, N. G.; Weixlbaumer, A.
10.1101/2024.03.19.585789 — biochemistry — Posted on 2024-03-19
1958 Evolutionary trajectory of TRPM2 channel activation by adenosine diphosphate ribose and calcium
Ma, C.; Luo, Y.; Zhang, C.; Cheng, C.; Hua, N.; Liu, X.; Wu, J.; Qin, L.; Yu, P.; Luo, J.; Yang, F.; Jiang, L.-H.; Zhang, G.; Yang, W.
10.1101/2024.03.18.584035 — evolutionary biology — Posted on 2024-03-19
1959 Lossless Single-Molecule Counting To Absolute QuantifyProteoforms
Gross, T.; Hundertmark, T.; Csiszar, V.; Sulyok, A. A.; Gross, N.; Breiden, M.; Kitschen, N.; von Groll, U.; Niemoller, C.; Sanchez-Martin, P.; Hein, A.; Gopffert, J.; Szoradi, T.; Luebbert, P.; Koltay, P.; Porschewski, P.; von Stetten, F.; Zengerle, R.; Jeney, C.
10.1101/2024.03.19.585761 — molecular biology — Posted on 2024-03-19
1961 A diverse gut virome from Drosophila melanogaster
Ansari, M. H.; Staubach, F.; Alacatli, N.; Obbard, D. J.
10.1101/2024.03.19.585549 — microbiology — Posted on 2024-03-19
1962 Molecular basis for the activation of the Fatty Acid Kinase complex of Staphylococcus aureus
Myers, M. J.; Xu, Z.; Ryan, B. J.; DeMars, Z. R.; Ridder, M. J.; Johnson, D. K.; Krute, C. N.; Flynn, T. S.; Kashipathy, M. M.; Battaile, K. P.; Schnicker, N. J.; Lovell, S.; Freudenthal, B. D.; Bose, J. L.
10.1101/2024.03.19.585040 — microbiology — Posted on 2024-03-19
1968 Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types
Blanton, L. V.; San Roman, A. K.; Wood, G.; Buscetta, A.; Banks, N.; Skaletsky, H.; Godfrey, A. K.; Pham, T. T.; Hughes, J. F.; Brown, L. G.; Kruszka, P.; Lin, A. E.; Kastner, D. L.; Muenke, M.; Page, D. C.
10.1101/2024.03.18.585578 — genomics — Posted on 2024-03-19
1970 The Genomic portrait of the Picene culture: new insights into the Italic Iron Age and the legacy of the Roman expansion in Central Italy.
Ravasini, F.; Niinemae, H.; Solnik, A.; de Gennaro, L.; Montinaro, F.; Hui, R.; Delpino, C.; Finocchi, S.; Giroldini, P.; Mei, O.; Cilli, E.; Hajiesmaeil, M.; Pistacchia, L.; Risi, F.; Giacometti, C.; Scheib, C. L.; Tambets, K.; Metspalu, M.; Cruciani, F.; D'Atanasio, E.; Trombetta, B.
10.1101/2024.03.18.585512 — genomics — Posted on 2024-03-19
1975 Multi-Site Investigation of Gut Microbiota in CDKL5 Deficiency Disorder Mouse Models: Targeting Dysbiosis to Improve Neurological Outcomes
Damiani, F.; Giuliano, M. G.; Cornuti, S.; Putignano, E.; Tognozzi, A.; Suckow, V.; Kalscheuer, V. M.; Tognini, P.
10.1101/2024.03.19.581742 — neuroscience — Posted on 2024-03-19
1976 The role of rat prelimbic cortex in decision making
Palmer, J. A.; White, S. R.; Lopez, K. C.; Laubach, M.
10.1101/2024.03.18.585593 — neuroscience — Posted on 2024-03-19
1980 Assembly of mTORC3 involves binding of ETV7 to two separate sequences in the mTOR kinase domain.
Zhan, J.; Harwood, F. C.; Have, S. T.; Lamond, A. I.; Halder, P.; Kriwacki, R.; Grosveld, G. C.
10.1101/2024.03.19.583970 — cancer biology — Posted on 2024-03-19
1981 LarvaTagger: Manual and automatic tagging of Drosophila larval behaviour
Laurent, F.; Blanc, A.; May, L.; Gandara, L.; Cocanougher, B. T.; Jones, B. M. W.; Hague, P.; Barre, C.; Vestergaard, C. L.; Crocker, J.; Zlatic, M.; Jovanic, T.; Masson, J.-B.
10.1101/2024.03.18.585197 — bioinformatics — Posted on 2024-03-19
1982 Exploring structural diversity across the protein universe with The Encyclopedia of Domains
Lau, A. M. C.; Bordin, N.; Kandathil, S. M.; Sillitoe, I.; Waman, V. P.; Wells, J.; Orengo, C.; Jones, D. T.
10.1101/2024.03.18.585509 — bioinformatics — Posted on 2024-03-19
1986 Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons
Jones, A. G.; Schaal, G.; Boye, A.; Creemers, M.; Derolez, V.; Desroy, N.; Fiandrino, A.; Mouton, T. L.; Simier, M.; Smith, N.; Ouisse, V.
10.1101/2022.08.18.504439 — ecology — Posted on 2024-03-19
1987 Distribution, ecology, and natural history of the recently rediscovered and critically endangered Santa Marta Sabrewing
Botero-Delgadillo, E.; Lara, C. E.; Vega, Y.; Santos, M. P.; Zarrate, D.; Cuervo, A. M.; Mittermeier, J. C.
10.1101/2024.03.18.581190 — ecology — Posted on 2024-03-19
1989 A programmable and automated optical electrowetting-on-dielectric (oEWOD) driven platform for massively parallel and sequential processing of single cell assay operations
Welch, L. G.; Estranero, J.; Tourlomousis, P.; Wootton, R. C. R.; Radu, V.; Gonzalez-Fernandez;, C.; Puchtler, T. J.; Murzeau, C. M.; Dieckmann, N. M. G.; Shibahara, A.; Longbottom, B. W.; Bryant, C. E.; Talbot, E. L.
10.1101/2024.03.19.585693 — cell biology — Posted on 2024-03-19
1993 Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics
Walker, T. J.; Reyes-Alvarez, E.; Hyndman, B. D.; Sugiyama, M. G.; Oliveira, L. C. B.; Rekab, A. N.; Crupi, M. J. F.; Cabral-Dias, R.; Guo, Q.; Dahia, P. L. M.; Richardson, D. S.; Antonescu, C. N.; Mulligan, L. M.
10.1101/2023.06.28.546955 — cancer biology — Posted on 2024-03-19
1994 Twist - torsion coupling in beating axonemes
Striegler, M.; Friedrich, B. M.; Diez, S.; Geyer, V. F.
10.1101/2024.03.18.585533 — biophysics — Posted on 2024-03-19
1995 Emergence of ion-channel mediated electrical oscillations in E. coli biofilms
Akabuogu, E. U.; Martorelli, V.; Krasovec, R.; Roberts, I. S.; Waigh, T. A.
10.1101/2022.11.09.515771 — biophysics — Posted on 2024-03-19
2000 Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression.
Pizzirusso, G.; Preka, E.; Goikolea, J.; Aguilar Ruiz, C.; Rodriguez Rodriguez, P.; Vazquez Cabrera, G.; Laterza, S.; Latorre-Leal, M.; Eroli, F.; Blomgren, K.; Maioli, S.; Nilsson, P.; Fragkopoulou, A.; Fisahn, A.; Arroyo-Garcia, L. E.
10.1101/2024.03.14.584993 — neuroscience — Posted on 2024-03-19
2001 A novel in vitro tubular model to recapitulate features of distal airways: the bronchioid
Maurat, E.; Raasch, K.; Leipold, A. M.; Henrot, P.; Zysman, M.; Prevel, R.; Trian, T.; Krammer, T.; Bergeron, V.; Thumerel, M.; Nassoy, P.; Berger, P.; Saliba, A.-E.; Andrique, L.; Recher, G.; Dupin, I.
10.1101/2023.12.06.569771 — physiology — Posted on 2024-03-19
2012 Multi-way modelling of oral microbial dynamics and host-microbiome interactions during induced gingivitis
van der Ploeg, G. R.; Brandt, B.; Keijser, B.; van der Veen, M.; Volgenant, C.; Zaura, E.; Smilde, A.; Westerhuis, J.; Heintz-Buschart, A.
10.1101/2024.03.18.585469 — systems biology — Posted on 2024-03-19
2014 Crosstalk between thrombospondin-1 and CD36 modulates platelet-RBC interaction limiting thrombosis and abdominal aneurysm formation
Krott, K. J.; Feige, T.; Bosbach, A.; Beele, A.; Krueger, I.; Reusswig, F.; Schickentanz-Dey, E.; Chadt, A.; Kelm, M.; Gerdes, N.; Pfeiler, S.; Jurk, K.; Kiouptsi, K.; Reinhardt, C.; Al-Hasani, H.; Kehrel, B.; Karray, S.; Schelzig, H.; Wagenhaueser, M.; Elvers, M.
10.1101/2024.03.18.585356 — pathology — Posted on 2024-03-19
2018 Nine high-quality Anas genomes provide new insights into Anas evolution and domestication
Zhang, Z.; Ni, Z.; Li, T.; Ning, M.; Gao, C.; Hu, J.; Han, M.; Yang, J.; Wu, F.; Chen, L.; Lu, L.; Wu, Z.; Ai, H.; Huang, Y.
10.1101/2024.03.17.585367 — genomics — Posted on 2024-03-19
2021 Map based cloning of CT2 and the pilot functional exploration in abiotic stress
Wang, C.; Zheng, Q.; Gao, Y.; Guo, Z.; Zheng, L.; Yang, J.; Tang, J.; zheng, x.; Shi, Y.
10.1101/2024.03.17.585181 — molecular biology — Posted on 2024-03-19
2022 Granzyme B-based CAR T cells block metastasis by eliminating circulating tumor cells
Sun, B.; Guo, J.; Yang, D.; Hu, Q.; Ma, H.; Tian, P.; Liu, N.; Lv, L.; Yan, L.; Hao, D.; Fu, M.; Gou, H.; Cao, D.; Liu, D.; Chen, N.; SHI, P.; Li, W.; Zhao, X.
10.1101/2024.03.18.585442 — immunology — Posted on 2024-03-19
2024 Normative growth modeling of brain morphology reveals neuroanatomical heterogeneity and biological subtypes in children with ADHD
Bu, X.; Zhao, Y.; Zheng, X.; Fu, Z.; Zhang, K.; Sun, X.; Cui, Z.; Xia, M.; Ma, L.; Liu, N.; Lu, J.; Zhao, G.; Ding, Y.; Deng, Y.; Wang, J.; Chen, R.; Zhang, H.; Men, W.; Wang, Y.; Gao, J.; Tan, S.; Sun, L.; Qin, S.; Tao, S.; Wang, Y.; Dong, Q.; Cao, Q.; Yang, L.; He, Y.
10.1101/2024.03.16.582202 — neuroscience — Posted on 2024-03-19
2025 Comprehensive evaluation of pipelines for diagnostic biomarkers of major depressive disorder using multi-site resting-state fMRI datasets
Takahara, Y.; Kashiwagi, Y.; Tokuda, T.; Yoshiomoto, J.; Sakai, Y.; Yamashita, A.; Yoshioka, T.; Takahashi, H.; Mizuta, H.; Kasai, K.; Kunimitsu, A.; Okada, N.; Itai, E.; Shinzato, H.; Yokoyama, S.; Masuda, Y.; Mitsuyama, Y.; Okada, G.; Okamoto, Y.; Itahashi, T.; Ota, H.; Hashimoto, R.-i.; Harada, K.; Yamagata, H.; Matsubara, T.; Matsuo, K.; Tanaka, S. C.; Imamizu, H.; Ogawa, K.; Momosaki, S.; Kawato, M.; Yamashita, O.
10.1101/2024.03.17.584538 — neuroscience — Posted on 2024-03-19
2028 ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma
Yu, V. Z.; So, S. S.; Lung, B. C.-c.; Hou, G. Z.; Wong, C. W.-y.; Chow, L. K.-y.; Chung, M. K.-y.; Wong, I. Y.-h.; Wong, C. L.-y.; Chan, D. K.-k.; Chan, F. S.-y.; Law, B. T.-t.; Xu, K.; Tan, Z. Z.; Lam, K.-o.; Lo, A. W.-i.; Lam, A. K.-y.; Kwong, D. L.-w.; Ko, J. M.-y.; Dai, W.; Law, S.; Lung, M. L.
10.1101/2024.03.17.585449 — cancer biology — Posted on 2024-03-19
2029 Dysregulation of cell state dynamics during early stages of serous endometrial carcinogenesis
Flesken-Nikitin, A.; Pirtz, M. G.; Ashe, C. S.; Ellenson, L. H.; Cosgrove, B. D.; Nikitin, A. Y.
10.1101/2024.03.15.585274 — cancer biology — Posted on 2024-03-19
2031 Defining focal neuroendocrine differentiation as a transcriptionally distinct form of prostate cancer pathology characterized by the expression of androgen receptors
Quezada Urban, R.; Keerthikumar, S.; Clark, A.; Wang, H.; Phipson, B.; Bakshi, A.; Ryan, A.; Thorne, H. J.; Taylor, R. A.; Lawrence, M. G.; Risbridger, G. P.; Toivanen, R.; Goode, D. L.
10.1101/2024.03.17.585125 — cancer biology — Posted on 2024-03-19
2033 Nanoparticle-mediated delivery of peptide-based degraders enables targeted protein degradation
Ghosal, S.; Robertus, C.; Wang, J.; Chan, H. W.; Alamgir, A.; Almonte, J.; Alabi, C. A.
10.1101/2024.03.17.584721 — bioengineering — Posted on 2024-03-19
2035 DNA metabarcoding revealed how time and space do matter -sex does not- in the dietary variation of the endangered Duponts Lark
Zurdo, J.; Bustillo-de la Rosa, D.; Barrero, A.; Gomez-Catasus, J.; Reverter, M.; Perez-Granados, C.; Garcia, J. T.; Vinuela, J.; Dominguez, J. C.; Morales, M. B.; Traba, J.
10.1101/2024.03.17.585437 — ecology — Posted on 2024-03-19
2037 The best of two worlds: using stacked generalization for integrating expert range maps in species distribution models
Oeser, J.; Zurell, D.; Mayer, F.; Coraman, E.; Toshkova, N.; Deleva, S.; Natradze, I.; Benda, P.; Ghazaryan, A.; Irmak, S.; Hasanov, N. A.; Guliyeva, G. G.; Gritsina, M.; Kuemmerle, T.
10.1101/2024.03.12.584552 — ecology — Posted on 2024-03-19
2040 Adipose tissue microvascular endothelial cells form a tight vascular barrier that selectively transcytoses fatty acid tracers
Schipper, R.; Ioannidou, A.; Maestri, A.; Baganha, F.; Werngren, O.; Oolofsson, P. S.; Malin, S. G.; Fisher, R. M.; Hagberg, C. E.
10.1101/2024.03.19.585709 — cell biology — Posted on 2024-03-19
2041 Development of covalent probes to capture Legionella pneumophila effector enzymes
van der Heden van Noort, G. J.; Kloet, M. S.; Mukhopadhyay, R.; Mukherjee, R.; Misra, M.; Jeong, M.; Talavera Ormeno, C. M. P.; Moutsiopoulou, A.; Tjokrodirijo, R. T. N.; van Veelen, P. A.; Shin, D.; Dikic, I.; Sapmaz, A.; Kim, R. Q.
10.1101/2024.03.19.585531 — cell biology — Posted on 2024-03-19
2042 Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels
Eiken, M. K.; Childs, C. J.; Brastrom, L. K.; Frum, T.; Plaster, E. M.; Shachaf, O.; Pfeiffer, S.; Levine, J. E.; Alysandratos, K.; Kotton, D. N.; Spence, J. R.; Loebel, C.
10.1101/2024.03.19.585720 — cell biology — Posted on 2024-03-19
2045 Genomic and phenotypic imprints of microbial domestication on cheese starter cultures
Somerville, V.; Thierer, N.; Schmidt, R. S.; Roetschi, A.; Braillard, L.; Haueter, M.; Berthoud, H.; Shani, N.; von Ah, U.; Mazel, F.; Engel, P.
10.1101/2024.03.19.585705 — microbiology — Posted on 2024-03-19
2046 Multi-omics analysis of aggregative multicellularity
Edelbroek, B.; Orzechowski Westholm, J.; Bergquist, J.; Soderbom, F.
10.1101/2024.03.19.585704 — microbiology — Posted on 2024-03-19
2047 A packaging signal-binding protein regulates the assembly checkpoint of integrative filamentous phages
Yeh, T.-Y.; Feehley, M. C.; Feehley, P. J.; Ooi, V. Y.; Hung, Y.-Y.; Wang, S.-C.; Contreras, G. P.
10.1101/2024.03.19.585677 — microbiology — Posted on 2024-03-19
2051 Id1, Spp1 and Pak3 are biomarkers of Smad4 and TGF-β1 dependency in conditional intestinal adenoma, organoids and colorectal cancer.
Surakhy, M.; Matheson, J.; Barnes, D.; Carter, E.; Hughes, J.; Bühnemann, C.; Sanegre, S.; Morreau, H.; Metz, P.; Imianowski, C. J.; HASSAN, A. B.
10.1101/2024.03.15.584288 — cancer biology — Posted on 2024-03-19
2052 Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in African American and European American patients with TNBC
Zhu, Q.; Balasubramanian, A.; Asirvatham, J. R.; Piyarathna, D. W. B.; Kaur, J.; Mohamed, N.; Wu, L.; Chatterjee, M.; Wang, S.; Pourfarrokh, N.; Rasaily, U.; Xu, Y.; Zheng, J.; Jebakumar, D.; Rao, A.; Chen, S.-h.; Li, Y.; Chang, E.; Li, X.; Aneja, R.; Zhang, X. H.- F.; Sreekumar, A.
10.1101/2024.03.17.585428 — cancer biology — Posted on 2024-03-19
2054 Concepts and methods for predicting viral evolution
Meijers, M.; Ruchnewitz, D.; Eberhardt, J.; Karmakar, M.; Łuksza, M.; Lässig, M.
10.1101/2024.03.19.585703 — biophysics — Posted on 2024-03-19
2062 Tuning non-linear mechanics in collagen hydrogels modulates three dimensional cellular morphotypes
Enriquez Martinez, M. A.; Wang, Z.; Ju, R. J.; Turunen, P.; Mata, J.; Gilbert, E. P.; Lauko, J.; Stehbens, S. J.; Rowan, A. E.
10.1101/2024.03.18.585457 — biophysics — Posted on 2024-03-19
2064 Phase Contrast Tomography (PCT)
Ma, Y.; Feng, W.; Lei, Y.; Ma, L.; Zheng, J.; An, S.; Liu, M.; Gao, P.
10.1101/2024.03.17.585445 — biophysics — Posted on 2024-03-19
2068 Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11
Stander, S.; Reboul, C. F.; Lee, S. N.; Williams, D.; Chandler, P. G.; Costa, M. G.; Hoke, D. E.; Jimma, J. D.; Fodor, J.; Fenalti, G.; Mannering, S. I.; Porebski, B. T.; Schofield, P.; Christ, D.; Buckle, M.; McGowan, S.; Elmlund, D.; Rand, K. D.; Buckle, A. M.
10.1101/2024.03.18.585568 — biochemistry — Posted on 2024-03-19
2069 "Stability and affinity evaluation of aptamers as a biorecognition system for testosterone and its analogs".
Medina-Benitez, A.; Garcia-Alonso, C. A.; Fragoso-Rodriguez, R.; Torres-Huerta, A. L.; Antonio-Perez, A.
10.1101/2024.03.18.585618 — biochemistry — Posted on 2024-03-19
2071 The somatic mutation landscape of normal gastric epithelium
Coorens, T. H. H.; Collord, G.; Jung, H.; Wang, Y.; Moore, L.; Hooks, Y.; Mahbubani, K.; Saeb-Parsy, K.; Campbell, P. J.; Martincorena, I.; Leung, S. Y.; Stratton, M. R.
10.1101/2024.03.17.585238 — genomics — Posted on 2024-03-19
2072 Geographical distribution, disease association and diversity of Klebsiella pneumoniae KL and O antigens in India: roadmap for vaccine development
Shamanna, V.; Srinivas, S.; Couto, N.; Nagaraj, G.; Sajankila, S. P.; Krishnappa, H. G.; Kumar, K. A.; Aanensen, D.; Lingegowda, R. K.; GHRU India Consortium,
10.1101/2024.03.15.585133 — genomics — Posted on 2024-03-19
2076 A numbers game: Mosquito-based arbovirus surveillance in two distinct geographic regions of Latin America
Mojica, J.; Arevalo, V.; Juarez, J. G.; Galarza, X.; Gonzalez, K.; Carrazco-Montalvo, A.; Suazo, H.; Harris, E.; Coloma, J.; Ponce, P.; Balmaseda, A.; Cevallos, V.
10.1101/2024.03.15.585246 — ecology — Posted on 2024-03-19
2078 A salmon fish model reveals genetic signals in brain associated with early maturation
Pashay Ahi, E.; Verta, J.-P.; Kurko, J.; Ruokolainen, A.; Singh, P.; Debes, P. V.; Erkinaro, J.; Primmer, C. R.
10.1101/2024.03.18.585557 — genetics — Posted on 2024-03-19
2079 High-resolution genomic ancestry reveals mobility in early medieval Europe
Speidel, L.; Silva, M.; Booth, T.; Raffield, B.; Anastasiadou, K.; Barrington, C.; Gotherstrom, A.; Heather, P.; Skoglund, P.
10.1101/2024.03.15.585102 — evolutionary biology — Posted on 2024-03-19
2081 Temporal dynamics and maturation of resting-state activity in preterm infants
Adibpour, P.; Nasser, H.; Pedoux, A.; Devisscher, L.; Elbaz, N.; Ghozland, C.; Hinnekens, E.; Neumane, S.; Kabdebon, C.; Lefebvre, A.; Kaminska, A.; Hertz-Pannier, L.; Heneau, A.; Sibony, O.; Alison, M.; Delanoe, C.; Delorme, R.; Barbu-Roth, M.; Biran, V.; Dubois, J.
10.1101/2024.03.19.585608 — neuroscience — Posted on 2024-03-19
2082 The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study
Rier, L.; Rhodes, N.; Pakenham, D.; Boto, E.; Holmes, N.; Hill, R. M.; Reina Rivero, G.; Shah, V.; Doyle, C.; Osborne, J.; Bowtell, R. W.; Taylor, M.; Brookes, M. J.
10.1101/2024.01.04.573933 — neuroscience — Posted on 2024-03-19
2083 Optimized dCas9 Transcription Activators for Plants
Zinselmeier, M.; Casas-Mollano, J. A.; Cors, J.; Sychla, A.; Heinsch, S.; Voytas, D.; Smanski, M.
10.1101/2022.06.10.495638 — plant biology — Posted on 2024-03-19
2084 Multiple paralogues and recombination mechanisms drive the high incidence of 22q11.2 Deletion Syndrome
Vervoort, L.; Dierckxsens, N.; Sousa Santos, M.; Meynants, S.; Souche, E.; Cools, R.; Heung, T.; Devriendt, K.; Peeters, H.; Mcdonald-mcginn, D.; Swillen, A.; Breckpot, J.; Emanuel, B. S.; Van Esch, H.; Bassett, A. S.; Vermeesch, J. R.
10.1101/2024.03.14.585046 — genetics — Posted on 2024-03-19
2085 Dysfunctional β-cell longevity in diabetes relies on high energy conservation and positive epistasis
Raval, K. H.; Jamshidi, N.; Seyran, B. S.; Salwinski, L.; Pillai, R. K.; Yang, L.; Ma, F.; Pellegrini, M.; Shin, J.; Yang, X.; Tudzarova, S.
10.1101/2024.03.18.585508 — cell biology — Posted on 2024-03-19
2086 Transformation of the drug ibuprofen by Priestia megaterium: Reversible glycosylation and generation of hydroxylated metabolites
Hinzke, T.; Schlüter, R.; Mikolasch, A.; Zühlke, D.; Müller, P.; Riedel, K.; Lalk, M.; Becher, D.; Sheikany, H.; Schauer, F.
10.1101/2024.03.18.585558 — microbiology — Posted on 2024-03-19
2087 2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase
Herdering, E.; Reif-Trauttmansdorff, T.; Kumar, A.; Habenicht, T.; Hochberg, G.; Bohn, S.; Schuller, J.; Schmitz, R. A.
10.1101/2024.03.18.585516 — microbiology — Posted on 2024-03-19
2089 Intra-species quantification reveals differences in activity and sleep levels in the yellow fever mosquito, Aedes aegypti
Ajayi, O.; Susanto, E. E.; Wang, L.; Kennedy, J.; Ledezma, A.; Harris, A.; Smith, E. S.; Chakraborty, S.; Wynne, N. E.; Sylla, M.; Akorli, J.; Otoo, S.; Rose, N. H.; Vinauger, C.; Benoit, J. B.
10.1101/2024.03.16.585223 — physiology — Posted on 2024-03-19
2090 Presynaptic Rac1 in the hippocampus selectively regulates working memory
Kim, J.; Bustamante, E.; Sotonyi, P.; Maxwell, N.; Parameswaran, P.; Kent, J. K.; Wetsel, W. C.; Soderblom, E. J.; Racz, B.; Soderling, S. H.
10.1101/2024.03.18.585488 — animal behavior and cognition — Posted on 2024-03-19
2091 Deciphering the Influence of Socioeconomic Status on Brain Structure: Insights from Mendelian Randomization
Xia, C.; Lu, Y.; Zhou, Z.; Marchi, M.; Kweon, H.; Ning, Y.; Liewald, D. C. M.; Anderson, E. L.; Koellinger, P. D.; Cox, S. R.; Boks, M. P.; Hill, W. D.
10.1101/2024.03.13.584410 — genetics — Posted on 2024-03-19
2092 miR-146a-5p mediates inflammation-induced β cell mitochondrial dysfunction and apoptosis
Krishnan, P.; Branco, R. C. S.; Weaver, S. A.; Chang, G.; Lee, C.-C.; Syed, F.; Evans-Molina, C.
10.1101/2024.03.18.585543 — molecular biology — Posted on 2024-03-19
2095 Human spermatogonial stem cells retain states with a foetal-like signature
Bush, S. J.; Nikola, R.; Han, S.; Suzuki, S.; Yoshida, S.; Simons, B. D.; Goriely, A.
10.1101/2024.03.18.585628 — cell biology — Posted on 2024-03-19
2097 GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding
Zou, J.; Jiang, M.; Xiao, R.; Sun, H.; Liu, H.; Peacock, T.; Tu, S.; Chen, T.; Guo, J.; Zhao, Y.; Barclay, W.; Xie, S.; Zhou, H.
10.1101/2024.03.18.585644 — microbiology — Posted on 2024-03-19
2098 Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein
Noone, D.; Isendoorn, M.; Hamers, S.; Keizer, M.; Wulffele, J. T.; van der Velden, T.; Dijkstra, D.; Trouw, L.; Filippov, D.; Sharp, T.
10.1101/2024.03.18.585147 — immunology — Posted on 2024-03-19
2099 ANKRD55 interacts with an IFT-B-like complex in microglia
Mena, J.; Navarro, R. T.; Diez-Garcia, J.; Azkargorta, M.; Aldekoa, A.; Fiat, A.; Ugidos-Damboriena, N.; Lindskog, C.; Pampliega, O.; Alloza, I.; Katoh, Y.; Nakayama, K.; Elortza, F.; Vandenbroeck, K.
10.1101/2024.03.18.584613 — immunology — Posted on 2024-03-19
2100 A web-based histology atlas for the freshwater Cladocera species Daphnia magna
Ngu, M. S.; Vanselow, D. X.; Zaino, C. R.; Lin, A. Y.; Copper, J. E.; Beaton, M.; Orsini, L.; Colbourne, J. K.; Cheng, K. C.; Ang, K. C.
10.1101/2022.03.09.483544 — zoology — Posted on 2024-03-19
2102 Metabolic priming of GD2 TRAC-CAR T cells during manufacturing promotes memory phenotypes while enhancing persistence
Cappabianca, D.; Pham, D.; Forsberg, M. H.; Bugel, M.; Tommasi, A.; Lauer, A.; Vidugiriene, J.; Hrdlicka, B.; McHale, A.; Sodji, Q.; Skala, M. C.; Capitini, C. M.; Saha, K.
10.1101/2024.01.31.575774 — bioengineering — Posted on 2024-03-19
2103 ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages
Bates, T. A.; Trank-Greene, M.; Nguyenla, X.; Anastas, A.; Gurmessa, S.; Merutka, I. R.; Dixon, S. D.; Shumate, A.; Groncki, A. R.; Parson, M. A.; Ingram, J. R.; Barklis, E.; Burke, J. E.; Shinde, U.; Ploegh, H. L.; Tafesse, F. G.
10.1101/2023.08.16.553641 — biochemistry — Posted on 2024-03-19
2104 Single-cell genomics and regulatory networks for 388 human brains
Emani, P. S.; Liu, J. J.; Clarke, D.; Jensen, M.; Warrell, J.; Gupta, C.; Meng, R.; Lee, C. Y.; Xu, S.; Dursun, C.; Lou, S.; Chen, Y.; Chu, Z.; Galeev, T.; Hwang, A.; Li, Y.; Ni, P.; Zhou, X.; PsychENCODE Consortium, ; Bakken, T. E.; Bendl, J.; Bicks, L.; Chatterjee, T.; Cheng, L.; Cheng, Y.; Dai, Y.; Duan, Z.; Flaherty, M.; Fullard, J. F.; Gancz, M.; Garrido-Martin, D.; Gaynor-Gillett, S.; Grundman, J.; Hawken, N.; Henry, E.; Hoffman, G. E.; Huang, A.; Jiang, Y.; Jin, T.; Jorstad, N. L.; Kawaguchi, R.; Khullar, S.; Liu, J.; Liu, J.; Liu, S.; Ma, S.; Margolis, M.; Mazariegos, S.; Moore, J.; M
10.1101/2024.03.18.585576 — genomics — Posted on 2024-03-19
2105 Post-GWAS functional analyses of CNTNAP5 suggests its role in glaucomatous neurodegeneration
Chakraborty, S.; Sarma, J.; Roy, S. S.; Mitra, S.; Bagchi, S.; Das, S.; Saha, S.; Mahapatra, S.; Bhattacharjee, S.; Maulik, M.; Acharya, M.
10.1101/2024.03.14.583830 — genetics — Posted on 2024-03-19
2107 Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years
Bougiouri, K.; Charlton, S.; Harris, A.; Carmagnini, A.; Piliciauskiene, G.; Feuerborn, T. R.; Scarsbrook, L.; Tabadda, K.; Blazevicius, P.; Parker, H. G.; Gopalakrishnan, S.; Larson, G.; Ostrander, E. A.; Irving-Pease, E. K.; Frantz, L. A. F.; Racimo, F.
10.1101/2024.03.15.585179 — evolutionary biology — Posted on 2024-03-19
2110 Cardiac Outflow tract septation defects in a DiGeorge syndrome model respond to Minoxidil treatment.
Aurigemma, I.; Ferrentino, R.; Krishnan, V. P.; Lanzetta, O.; Angelini, C.; Illingworth, E.; Baldini, A.
10.1101/2024.03.18.585569 — developmental biology — Posted on 2024-03-19
2111 Electrical Impedance Spectroscopy Quantifies Skin Barrier Function in Organotypic In Vitro Epidermis Models
van den Brink, N. J. M.; Pardow, F.; Meesters, L. D.; van Vlijmen-Willems, I.; Rodijk-Olthuis, D.; Niehues, H.; Jansen, P. A. M.; Roelofs, S. H.; Brewer, M. G.; van den Bogaard, E. H.; Smits, J. P. H.
10.1101/2024.03.18.585587 — developmental biology — Posted on 2024-03-19
2113 Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infections
Lasaviciute, G.; Tariq, K.; Sugathan, A.; Quin, J. E.; Bujila, I.; Skorokhod, O.; Troye-Blomberg, M.; Sverremark-Ekstrom, E.; Ostlund Farrants, A.-K.
10.1101/2024.03.18.585548 — cell biology — Posted on 2024-03-19
2115 A random mutagenesis screen enriched for missense mutations in bacterial effector proteins.
Urbanus, M. L.; Zheng, T. M.; Khusnutdinova, A. N.; Banh, D.; Mount, H. O.; Gupta, A.; Stogios, P. J.; Savchenko, A.; Isberg, R. R.; Yakunin, A. F.; Ensminger, A. W.
10.1101/2024.03.14.585084 — microbiology — Posted on 2024-03-19
2116 Developmental pyrethroid exposure disrupts folate metabolism in mouse brain
Curtis, M. A.; Saferin, N.; Nguyen, J. H.; Imami, A. S.; Neifer, K. L.; Miller, G. W.; Burkett, J. P.
10.1101/2023.10.13.562226 — neuroscience — Posted on 2024-03-19
2119 Spiking GABAergic OPC tumor cells prolong survival in IDH1 mutant glioma
Curry, R. N.; Ma, Q.; McDonald, M. F.; Ko, Y.; Srivastava, S.; Chin, P.-S.; He, P.; Lozzi, B.; Aiba, I.; Meyer, J.; Jing, J.; Wang, S.; Harmanci, A. O.; Athukuri, P.; Noebels, J.; Arenkiel, B.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2024.03.02.583026 — cancer biology — Posted on 2024-03-19
2120 Tumor microenvironmental determinants of high-risk DCIS progression
Glencer, A.; Ramalingam, K.; Schindler, N.; Mori, H.; Ghule, P.; Lee, K. C.; Nachmanson, D.; Officer, A.; Harismendy, O.; Stein, J. L.; Stein, G.; Weaver, D.; Yau, C.; Hirst, G. L.; Campbell, M. J.; Esserman, L. J.; Borowsky, A. D.
10.1101/2023.12.01.569676 — cancer biology — Posted on 2024-03-19
2121 Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting
Wu, Y.; Yan, Y.; Yang, Y.; Bian, S.; Rivetta, A.; Allen, K.; Sigworth, F. J.
10.1101/2023.06.02.543446 — biophysics — Posted on 2024-03-19
2123 Lateral Flow Assays Biotesting by Utilizing Plasmonic Nanoparticles Made of Inexpensive Metals - Replacing Colloidal Gold
Bahamondes Lorca, V. A.; Avalos-Ovando, O. R.; Sikeler, C.; Ijäs, H.; Santiago, E. Y.; Skelton, E.; Wang, Y.; Yang, R.; Cimatu, K. L. A.; Baturina, O.; Wang, Z.; Liu, J.; Slocik, J. M.; Wu, S.; Ma, D.; Pastukhov, A. I.; Kabashin, A.; Kordesch, M. E.; Govorov, A.
10.1101/2024.01.08.574723 — biophysics — Posted on 2024-03-19
2124 sincFold: end-to-end learning of short- and long-range interactions in RNA secondary structure
Bugnon, L. A.; Di Persia, L.; Gerard, M.; Raad, J.; Prochetto, S.; Fenoy, E.; Chorostecki, U.; Ariel, F.; Stegmayer, G.; Milone, D. H.
10.1101/2023.10.10.561771 — bioinformatics — Posted on 2024-03-19
2125 Gapless assembly of complete human and plant chromosomes using only nanopore sequencing
Koren, S.; Bao, Z.; Guarracino, A.; Ou, S.; Goodwin, S.; Jenike, K. M.; Lucas, J.; McNulty, B.; Park, J.; Rautianinen, M.; Rhie, A.; Roelofs, D.; Schneiders, H.; Vrijenhoek, I.; Nijbroek, K.; Ware, D.; Schatz, M. C.; Garrison, E.; Huang, S.; McCombie, W. R.; Miga, K. H.; Wittenberg, A. H. J.; Phillippy, A. M.
10.1101/2024.03.15.585294 — bioinformatics — Posted on 2024-03-19
2127 Unraveling a novel dual-function regulatory element showing epistatic interaction with a variant that escapes genome-wide association studies.
Adjemout, M.; Nisar, S.; Escandell, A.; Huu, H. T. N.; Torres, M.; Thiam, A.; Manosalva, I.; Mbengue, B.; Dieye, A.; Spicuglia, S.; Rihet, P.; Marquet, S.
10.1101/2024.03.18.585566 — genomics — Posted on 2024-03-19
2128 Transcriptional Determinism and Stochasticity Contribute to the Complexity of Autism Associated SHANK Family Genes
Lu, X.; Ni, P.; Suarez-Meade, P.; Yu, M.; Forrest, E. N.; Wang, G.; Wang, Y.; Quinones-Hinojosa, A.; Gerstein, M.; Jiang, Y.-h.
10.1101/2024.03.18.585480 — genetics — Posted on 2024-03-19
2129 Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC
Zhang, H.; Peyton, L. L.; McCarroll, A. G.; Guerrerro, S. D. d. L.; Zhang, S.; Gowda, P.; Sirkin, D. J. M.; El Achwah, M.; Duhe, A.; Wood, W. G.; Jamison, B.; Tracy, G.; Pollak, R.; Hart, R. P.; Pato, C. N.; Mulle, J. G.; Sanders, A. R.; Pang, Z. P.; Duan, J.
10.1101/2024.03.18.585542 — genetics — Posted on 2024-03-19
2132 Deciphering novel TCF4-driven mechanisms underlying a common triplet repeat expansion-mediated disease
Bhattacharyya, N.; Chai, N.; Hafford-Tear, N. J.; Sadan, A. N.; Szabo, A.; Zarouchlioti, C.; Jedlickova, J.; Leung, S. K.; Liao, T.; Dudakova, L.; Skalicka, P.; Parekh, M.; Moghul, I.; Jeffries, A. R.; Cheetham, M. E.; Muthusamy, K.; Hardcastle, A. J.; Pontikos, N.; Liskova, P.; Tuft, S. J.; Davidson, A. E.
10.1101/2023.03.29.534731 — molecular biology — Posted on 2024-03-19
2133 PPFlow: Target-aware Peptide Design with Torsional Flow Matching
Lin, H.; Zhang, O.; Zhao, H.; Jiang, D.; Wu, L.; Liu, Z.; Huang, Y.; Li, S. Z.
10.1101/2024.03.07.583831 — molecular biology — Posted on 2024-03-19
2134 Primary nasal viral infection rewires the tissue-scale memory response
Kazer, S. W.; Match, C. M.; Langan, E. M.; Messou, M.-A.; LaSalle, T. J.; O'Leary, E.; Marbourg, J.; Naughton, K.; von Andrian, U. H.; Ordovas-Montanes, J.
10.1101/2023.05.11.539887 — immunology — Posted on 2024-03-19
2135 Neurophysiology of perceptual decision-making and its alterations in attention deficit hyperactivity disorder (ADHD)
Biabani, M.; Walsh, K.; Zhou, S.-H.; Wagner, J.; Johnstone, A.; Paterson, J.; Johnson, B. P.; Loughnane, G. M.; O'Connell, R. G.; Bellgrove, M. A.
10.1101/2023.12.04.569762 — neuroscience — Posted on 2024-03-19
2138 Development and Characterization of a low intensity vibrational system for microgravity studies
Khan, O. M.; Gasperini, W.; Neccessary, C.; Jacobs, Z.; Perry, S.; Kuehl, P.; Nelson, K.; Gamble, P.; DeLeon, M.; Howard, S.; Zavala, A.; Farach-Carson, M. C.; Blaber, E. A.; Wu, D.; Satici, A.; Uzer, G.
10.1101/2023.11.20.567870 — bioengineering — Posted on 2024-03-19
2145 Foveolar drusen decrease fixation stability in presymptomatic AMD
Murari, J.; Gautier, J.; Daout, J.; Krafft, L.; Senee, P.; Mece, P.; Seiple, W.; Grieve, K.; Sheynikhovich, D.; Meimon, S.; Paques, M.; Arleo, A.
10.1101/2023.10.09.560481 — neuroscience — Posted on 2024-03-18
2147 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making
Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.
10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-03-18
2148 Cortical Face-Selective Responses Emerge Early in Human Infancy
Kosakowski, H. L.; Cohen, M. A.; Herrera, L.; Nichoson, I.; Kanwisher, N. G.; Saxe, R.
10.1101/2021.12.04.471085 — neuroscience — Posted on 2024-03-19
2149 Endocannabinoid and neuroplasticity-related changes as susceptibility factors in a rat model of posttraumatic stress disorder
Szente, L.; Balla, G. Y.; Varga, Z. K.; Toth, B.; Biro, L.; Balogh, Z.; Hill, M. N.; Toth, M.; Mikics, E.; Aliczki, M.
10.1101/2024.03.06.583339 — neuroscience — Posted on 2024-03-19
2152 The Chloroplast RNA Binding Protein CP29A supports rbcL expression during cold acclimation
Lenzen, B.; Roesch, F.; Ruwe, H.; Kachariya, N.; Legen, J.; Sattler, M.; Small, I. D.; Schmitz-Linneweber, C.
10.1101/2023.11.24.568587 — plant biology — Posted on 2024-03-18
2155 Developmental Regulation of Alternative Polyadenylation in an Adult Stem Cell Lineage
Gallicchio, L.; Reis Matias, N.; Morales-Polanco, F.; Nava, I.; Stern, S.; Zeng, Y.; Fuller, M. T.
10.1101/2024.03.18.585561 — developmental biology — Posted on 2024-03-18
2156 RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses
Rahjouei, A.; Kabrani, E.; Berruezo-Llacuna, M.; Altwasser, R.; Delgado-Benito, V.; Pavri, R.; Di Virgilio, M.
10.1101/2023.07.18.549543 — immunology — Posted on 2024-03-18
2157 Primate Saccade Rhythmicity
Näher, T.; Zhang, Y.; Pandinelli, M.; Fries, P.
10.1101/2023.09.27.559710 — neuroscience — Posted on 2024-03-18
2158 A novel nabelschnur protein regulates segregation of the kinetoplast DNA in Trypanosoma brucei
Cadena, L. R.; Hammond, M.; Tesarov, M.; Chmelova, L.; Svobodova, M.; Durante, I. M.; Yurchenko, V.; Lukes, J.
10.1101/2024.03.18.585547 — molecular biology — Posted on 2024-03-18
2160 A Protein Language Model for Exploring Viral Fitness Landscapes
Ito, J.; Strange, A.; Liu, W.; Joas, G.; Lytras, S.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Sato, K.
10.1101/2024.03.15.584819 — microbiology — Posted on 2024-03-18
2162 The evolutionary and molecular history of a chikungunya virus outbreak lineage
Krambrich, J.; Mihalic, F.; Gaunt, M. W.; Bohlin, J.; Hesson, J.; Lundkvist, A.; de Lamballerie, X.; Li, C.; Shi, W.; Pettersson, J. H.- O.
10.1101/2024.03.15.585156 — microbiology — Posted on 2024-03-18
2163 Fitness Factor Genes Conserved within the Multi-species Core Genome of Gram-negative Enterobacterales Species Contribute to Bacteremia Pathogenesis
Mobley, H. L. T.; Anderson, M. T.; Moricz, B. L.; Severin, G. S.; Holmes, C. L.; Ottosen, E. N.; Eichler, T.; Gupta, S.; Paudel, S.; Sinha, R.; Mason, S.; Himpsl, S. D.; Brown, A. N.; Gaca, M. L.; Kiser, C. M.; Clarke, T. H.; Fouts, D. E.; DiRita, V. J.; Bachman, M. A.
10.1101/2024.03.18.585282 — microbiology — Posted on 2024-03-18
2164 Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations
Nishijima, S.; Stankevic, E.; Aasmets, O.; Schmidt, T. S.; Nagata, N.; Keller, M. I.; Ferretti, P.; Juel, H.; Fullam, A.; Schudoma, C.; Robbani, S. M.; Hansen, J. K.; Holm, L. A.; Israelsen, M.; Schierwagen, R.; Torp, N.; Arumugam, M.; Bendtsen, F.; Broens, C.; Fonvig, C. E.; Holm, J.-C.; Nielsen, T.; Pedersen, J. S.; Thiele, M. S.; Trebicka, J.; Org, E.; Krag, A.; Hansen, T.; Kuhn, M.; Bork, P.
10.1101/2024.03.18.584290 — microbiology — Posted on 2024-03-18
2166 Identification of unique and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries
Akaberi, D.; Pourghasemi Lati, M.; Krambrich, J.; Berger, J.; Strandback, E.; Turunen, P.; Gullberg, H.; Moche, M.; Chinthakindi, P. K.; Nyman, T.; Sandstrom, A.; Jarhult, J. D.; Sandberg, K.; Lundkvist, A.; Verho, O.; Lennerstrand, J.
10.1101/2024.03.16.585341 — microbiology — Posted on 2024-03-18
2168 Role of socioeconomic factors and interkingdom crosstalk in the dental plaque microbiome in early childhood caries
Khan, M. W.; de Jesus, V. C.; Mittermuller, B.-A.; Sareen, S.; Lee, V.; Schroth, R. J.; Hu, P.; Chelikani, P.
10.1101/2024.03.12.584708 — microbiology — Posted on 2024-03-18
2169 A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to copper stress
Leprevost, L.; Junger, S.; Lippens, G.; Guillaume, C.; Sicoli, G.; Oliveira Correia, L.; Rivera-Millot, A.; Billon, G.; Henry, C.; Antoine, R.; Dubiley, S.; Zirah, S.; Li, Y.; Jacob-Dubuisson, F.
10.1101/2024.03.18.585515 — microbiology — Posted on 2024-03-18
2170 Modulation of SARS-CoV-2 spike binding to ACE2 throughconformational selection
Saha, P.; Fernanadez, I.; Sumbul, F.; Valotteau, C.; Kostrz, D.; Meola, A.; Baquero, E.; Sharma, A.; Portman, J. R.; Stransky, F.; Boudier, T.; Guardado Calvo, P.; Gosse, C.; Strick, T.; Rey, F. A.; Rico, F.
10.1101/2024.03.15.585207 — biophysics — Posted on 2024-03-18
2173 The Candida auris Hog1 MAP kinase is essential for the colonization of murine skin and intradermal persistence
Shivarathri, R.; Chauhan, M.; Datta, A.; Das, D.; Karuli, A.; Jenull, S.; Kuchler, K.; Thangamani, S.; Chowdhary, A.; Desai, J. V.; Chauhan, N.
10.1101/2024.03.18.585572 — microbiology — Posted on 2024-03-18
2174 Structural diversity and clustering of bacterial flagellar outer domains
Fields, J. L.; Zhang, H.; Bellis, N. F.; Petersen, H. A.; Halder, S. K.; Rich-New, S. T.; Wu, H.; Wang, F.
10.1101/2024.03.18.585621 — microbiology — Posted on 2024-03-18
2177 Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin
Liu, T.; Reiser, W. K.; Tan, T. J. C.; Lv, H.; Rivera-Cardona, J.; Heimburger, K.; Wu, N. C.; Brooke, C. B.
10.1101/2024.03.18.585603 — microbiology — Posted on 2024-03-18
2178 Binding of SARS-CoV-2 nucleocapsid protein to uninfected epithelial cells induces antibody-mediated complement deposition
Fahoum, J.; Billan, M.; Varga, J. K.; Padawer, D.; Elgrably-Weiss, M.; Basu, P.; Stolovich-Rain, M.; Baraz, L.; Kumari, S.; Oiknine-Dijan, E.; Kumar, M.; Cohen-Kfir, E.; Zelig, O.; Mayer, G.; Isupov, M. N.; Wolf, D. G.; Altuvia, S.; Wiener, R.; Schueler-Furman, O.; Rouvinski, A.
10.1101/2024.03.17.585388 — immunology — Posted on 2024-03-18
2179 Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer
Du, W.; Noyan, F.; McCallion, O.; Drosdek, V.; Kath, J.; Glaser, V.; Fuster-Garcia, C.; Yang, M.; Stein, M.; Weber, O.; Polansky, J. K.; Cathomen, T.; Jaeckel, E.; Hester, J.; Issa, F.; Volk, H.-D.; Schmueck-Henneresse, M.; Reinke, P.; Wagner, D. L.
10.1101/2024.03.18.584896 — immunology — Posted on 2024-03-18
2181 Atomically accurate de novo design of single-domain antibodies
Bennett, N. R.; Watson, J. L.; Ragotte, R. J.; Borst, A. J.; See, D. L.; Weidle, C.; Biswas, R.; Shrock, E. L.; Leung, P. J. Y.; Huang, B.; Goreshnik, I.; Ault, R.; Carr, K. D.; Singer, B.; Criswell, C.; Vafeados, D.; Garcia Sanchez, M.; Kim, H. M.; Vazquez Torres, S.; Chan, S.; Baker, D.
10.1101/2024.03.14.585103 — bioengineering — Posted on 2024-03-18
2182 Neural speech tracking in newborns: prenatal learning and contributing factors
Florea, C.; Riemann, M.; Schmidt, F.; Preiss, J.; Reisenberger, E.; Angerer, M.; Ameen, M.; Heib, D. P. J.; Roehm, D.; Schabus, M.
10.1101/2024.03.18.585222 — developmental biology — Posted on 2024-03-18
2184 Nfib regulates progenitor competence in maturation of GABAergic neurons
Kotlyarenko, Y.; Bright, A. R.; Neuhaus, F.; Rodrigues, D.; Vitali, I.; Myoga, M. H.; Mayer, C.
10.1101/2024.03.18.585524 — neuroscience — Posted on 2024-03-18
2185 Neurodevelopmentally rooted epicenters in schizophrenia: sensorimotor-association spatial axis of cortical thickness alterations
Fan, Y.-S.; Xu, Y.; Hettwer, M. D.; Yang, P.; Sheng, W.; Wang, C.; Yang, M.; Kirschner, M.; Valk, S. L.; Chen, H.
10.1101/2024.03.13.584752 — neuroscience — Posted on 2024-03-18
2188 Consequences of neuronal morphology for spatially precise optogenetic stimulation
Berling, D.; Baroni, L.; Chaffiol, A.; Gauvain, G.; Picaud, S.; Antolik, J.
10.1101/2024.03.18.585466 — neuroscience — Posted on 2024-03-18
2189 In vivo optogenetics using a Utah Optrode Array with enhanced light output and spatial selectivity
McAlinden, N.; Reiche, C. F.; Clark, A.; Scharf, R.; Cheng, Y.; Sharma, R.; Rieth, L.; Dawson, M. D.; Angelucci, A.; Mathieson, K.; Blair, S.
10.1101/2024.03.18.585479 — neuroscience — Posted on 2024-03-18
2190 A brain-to-text framework of decoding natural tonal sentences
Zhang, D.; Wang, Z.; Qian, Y.; Zhao, Z.; Liu, Y.; Hao, X.; Li, W.; Lu, S.; Zhu, H.; Chen, L.; Xu, K.; Li, Y.; Wu, J.; Lu, J.
10.1101/2024.03.16.585337 — neuroscience — Posted on 2024-03-18
2196 Dynamics of Brain Connectivity across the Alzheimer's Disease Spectrum: a magnetoencephalography study
Carrasco-Gomez, M.; Garcia-Colomo, A.; Cabrera-Alvarez, J.; Bruna, R.; Santos, A.; Maestu, F.
10.1101/2024.03.14.584574 — neuroscience — Posted on 2024-03-18
2198 Parent attention-orienting behavior is associated with neural entropy in infancy
Williams, C. L.; Belkowitz, A. R.; Nance, M. G.; Mortman, E. T.; Bae, S.; Ahmed, S.-B.; Puglia, M. H.
10.1101/2024.03.14.585061 — neuroscience — Posted on 2024-03-18
2202 VLK drives extracellular phosphorylation of EphB2 to govern the EphB2-NMDAR interaction and injury-induced pain
Srikanth, K. D.; Elahi, H.; Chander, P.; Washburn, H. R.; Hassler, S.; Mwirigi, J. M.; Kume, M.; Loucks, J.; Arjarapu, R.; Hodge, R.; Shiers, S. I.; Sankaranarayanan, I.; Erdjument-Bromage, H.; Neubert, T. A.; Campbell, Z. T.; Paik, R.; Price, T. J.; Dalva, M. B.
10.1101/2024.03.18.585314 — neuroscience — Posted on 2024-03-18
2203 CACNA1A haploinsufficiency leads to reduced synaptic function and increased intrinsic excitability
Hommersom, M. P.; Doorn, N.; Puvogel, S.; Lewerissa, E. I.; Mordelt, A.; Ciptasari, U.; Kampshoff, F.; Dillen, L.; van Beusekom, E.; Oudakker, A.; Kogo, N.; Frega, M.; Schubert, D.; van de Warrenburg, B. P. C.; Nadif Kasri, N.; van Bokhoven, H.
10.1101/2024.03.18.585506 — neuroscience — Posted on 2024-03-18
2204 Characterising the stimulus-response function of mouse C-low threshold mechanoreceptors to mechanical stimuli in vivo
Semizoglou, E.; Lo-Re, L.; Middleton, S. J.; Perez Sanchez, J.; Tufarelli, T.; Bennett, D. L.; Chisholm, K. I.
10.1101/2024.03.18.585483 — neuroscience — Posted on 2024-03-18
2205 How to measure functional connectivity using resting-state fMRI? A comprehensive empirical exploration of different connectivity metrics
Roell, L.; Wunderlich, S.; Roell, D.; Raabe, F.; Wagner, E.; Shi, Z.; Schmitt, A.; Falkai, P.; Stoecklein, S.; Keeser, D.
10.1101/2024.03.18.585458 — neuroscience — Posted on 2024-03-18
2206 Evaluating a Novel High-Density EEG Sensor Net Structure for Improving Inclusivity in Infants with Curly or Tightly Coiled Hair
Mlandu, N.; McCormick, S. A.; Davel, L.; Zieff, M. R.; Bradford, L.; Herr, D.; Jacobs, C. A.; Khumalo, A.; Knipe, C.; Madi, Z.; Mazubane, T.; Methola, B.; Mhlakwaphalwa, T.; Miles, M.; Goolam Nabi, Z.; Negota, R.; Nkubungu, K.; Pan, T.; Samuels, R.; Williams, S.; Williams, S. R.; Avery, T.; Foster, G.; Donald, K. A.; Gabard-Durnam, L. J.
10.1101/2024.03.18.584988 — neuroscience — Posted on 2024-03-18
2209 Twist - torsion coupling in beating axonemes
Striegler, M.; Friedrich, B. M.; Diez, S.; Geyer, V. F.
10.1101/2024.03.18.585533 — biophysics — Posted on 2024-03-18
2211 Genome-Wide Association Study in Outbred Heterogeneous Stock Rats Identifies Multiple Loci for the Incentive Salience of Reward Cues.
King, C. P.; Chitre, A. S.; Leal-Gutierrez, J. D.; Tripi, J. A.; Hughson, A.; Horvath, A.; Lamparelli, A. C.; George, A.; Martin, C.; St. Pierre, C. L.; Bimschleger, H. V.; Gao, J.; Cheng, R.; Nguyen, K.-M.; Holl, K. L.; Polesskaya, O.; Ishiwari, K.; Chen, H.; Solberg-Woods, L. C.; Palmer, A. A.; Robinson, T. E.; Flagel, S. B.; Meyer, P. J.
10.1101/2024.03.13.584852 — neuroscience — Posted on 2024-03-18
2212 Mitochondria drive microglial NRLP3 inflammasome activation via TSPO
Singh, A.; Rigon, M.; Caldeira, M.; Faccenda, D.; Xia, D.; Lopez-Tremoleda, J.; Falah Hassan Al-Khateeb, Z.; Guo, T.; Abeti, R.; Giunti, P.; Campanella, M.
10.1101/2024.03.18.585507 — cell biology — Posted on 2024-03-18
2213 Metastatic site influences driver gene function in pancreatic cancer
Tsanov, K. M.; Barriga, F. M.; Ho, Y.-J.; Alonso-Curbelo, D.; Livshits, G.; Koche, R. P.; Baslan, T.; Simon, J.; Tian, S.; Wuest, A. N.; Luan, W.; Wilkinson, J. E.; Masilionis, I.; Dimitrova, N.; Iacobuzio-Donahue, C. A.; Chaligne, R.; Pe'er, D.; Massague, J.; Lowe, S. W.
10.1101/2024.03.17.585402 — cancer biology — Posted on 2024-03-18
2215 Chloroplastic ascorbate acts as a regulatory hub in plant metabolism regardless of oxidative stress
Toth, D.; Tengolics, R.; Aarabi, F.; Karlsson, A.; Vidal-Meireles, A.; Kovacs, L.; Kuntam, S.; Kormoczi, T.; Fernie, A. R.; Hudson, E.; Papp, B.; Toth, S. Z.
10.1101/2024.03.14.585081 — plant biology — Posted on 2024-03-18
2216 Biosurfer for systematic tracking of regulatory mechanisms leading to protein isoform diversity
Murali, M.; Saquing, J.; Lu, S.; Gao, Z.; Jordan, B.; Wakefield, Z.; Fiszbein, A.; Cooper, D.; Castaldi, P.; Korkin, D.; Sheynkman, G.
10.1101/2024.03.15.585320 — genomics — Posted on 2024-03-18
2218 Highly Pathogenic Avian Influenza A (H5N1) Suspected in penguins and shags on the Antarctic Peninsula and West Antarctic Coast
Leon, F.; Le Bohec, C.; Pizarro, E. J.; Baille, L.; Cristofari, R.; Houstin, A.; Zitterbart, D. P.; Barriga, G.; Poulin, E.; Vianna, J. A.
10.1101/2024.03.16.585360 — genetics — Posted on 2024-03-18
2219 Endosomal sorting protein SNX4 limits synaptic vesicle docking and release
Poppinga, J.; Barret, N. J.; Cornelisse, L. N.; Verhage, M.; van Weering, J. R. T.
10.1101/2024.03.15.584406 — cell biology — Posted on 2024-03-18
2220 Moonlighting on the Fasciola hepatica tegument: enolase, a glycolytic enzyme, interacts with the extracellular matrix and fibrinolytic system of the host
O'Kelly, E.; Cwiklinski, K.; De Marco Verissimo, C.; Calvani, N. E. D.; Lopez Corrales, J.; Jewhurst, H.; Flaus, A.; Lalor, R.; Serrat, J.; Dalton, J. P.; Gonzalez-Miguel, J.
10.1101/2024.03.15.585155 — molecular biology — Posted on 2024-03-18
2224 Translation of monosynaptic circuits underlying amygdala fMRI neurofeedback training
Trambaiolli, L. R.; Maffei, C.; Dann, E.; Biazoli, C.; Bezgin, G.; Yendiki, A.; Haber, S.
10.1101/2024.03.15.585281 — neuroscience — Posted on 2024-03-18
2225 Neural dynamics of semantic control underlying generative storytelling
Rastelli, C.; Greco, A.; Finocchiaro, C.; Penazzi, G.; Braun, C.; De Pisapia, N.
10.1101/2024.03.16.584998 — neuroscience — Posted on 2024-03-18
2226 Validation of Enhancer Regions in Primary Human Neural Progenitor Cells using Capture STARR-seq
Gaynor-Gillett, S. C.; Cheng, L.; Shi, M.; Liu, J.; Wang, G.; Spector, M.; Flaherty, M.; Wall, M.; Hwang, A.; Gu, M.; Chen, Z.; Chen, Y.; PsychENCODE Consortium, ; Moran, J. R.; Zhang, J.; Lee, D.; Gerstein, M.; Geschwind, D.; White, K. P.
10.1101/2024.03.14.585066 — neuroscience — Posted on 2024-03-18
2228 Discovery of active mouse, plant and fungal cytochrome P450s in endogenous proteomes and upon expression in planta.
Font Farre, M.; Brown, D.; Toth, R.; Mahadevan, C.; Brazier-Hicks, M.; Morimoto, K.; Kaschani, F.; Sinclair, J.; Dale, R.; Hall, S.; Morris, M.; Kaiser, M.; Wright, A. T.; Burton, J.; van der Hoorn, R. A. L.
10.1101/2024.03.18.585456 — plant biology — Posted on 2024-03-18
2232 De novo PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription
Love, L.; Jutte, B. B.; Lindqvist, B.; Thomas, N. A.; Kieri, O.; Nowak, P.; Svensson, J. P.
10.1101/2024.03.17.583304 — microbiology — Posted on 2024-03-18
2234 Tobacco Smoke Exposure is Characterized by a Distinct Nasal Rhinotype in a Pediatric Population
Monaco, H.; Elaiho, C.; Liu, B.; Chan, T.; Cantor, A.; Collaco, J. M.; McGrath-Morrow, S.; Wilson, K.; Clemente, J. C.
10.1101/2024.03.15.585112 — microbiology — Posted on 2024-03-18
2237 Genome-wide CRISPRa screens nominate modulators of CAR T cell survival within distinct tumor cytokine milieus
Curtis, B. C.; Spurrell, C. H.; Flint, L.; Lande, A. M.; Leonardi, M.; Rosser, J. M.; Valdez, A.; Murren, N.; Chai, T.; Fitzgerald, M.; Martinez-Reyes, J.; Saxby, C. P.; Oda, S. K.; Jensen, M. C.
10.1101/2024.03.16.583115 — immunology — Posted on 2024-03-18
2238 Two long-axis dimensions of hippocampal cortical integration support memory function across the adult lifespan
Nordin, K.; Pedersen, R.; Falahati, F.; Johansson, J.; Grill, F.; Andersson, M.; Korkki, S. M.; Backman, L.; Zalesky, A.; Rieckmann, A.; Nyberg, L.; Salami, A.
10.1101/2023.03.24.534115 — neuroscience — Posted on 2024-03-18
2240 Single neurons and networks in the claustrum integrate input from widespread cortical sources
Shelton, A. M.; Oliver, D. K.; Lazarte, I. P.; Grimstvedt, J. S.; Kapoor, I.; Swann, J. A.; Ashcroft, C. A.; Williams, S. N.; Conway, N.; Tir, S.; Robinson, A.; Peirson, S. N.; Akam, T.; Kentros, C.; Witter, M. P.; Butt, S. J.; Packer, A. M.
10.1101/2022.05.06.490864 — neuroscience — Posted on 2024-03-18
2241 Reduced avoidance bias to social threat signals in women taking oral contraceptives
Thurley, J.; Buades Rotger, M.; Serfling, G.; Howaldt, T.; Reisch, N.; Kramer, U. M.
10.1101/2023.11.13.566589 — neuroscience — Posted on 2024-03-18
2242 Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections
Schupp, P. G.; Shelton, S. J.; Brody, D. J.; Eliscu, R.; Johnson, B. E.; Mazor, T.; Kelley, K. W.; Potts, M. B.; McDermott, M. W.; Huang, E. J.; Lim, D. A.; Pieper, R. O.; Berger, M. S.; Costello, J. F.; Phillips, J. J.; Oldham, M. C.
10.1101/2023.06.21.545365 — cancer biology — Posted on 2024-03-18
2243 Lack of dominant-negative activity for tumor-associated ZNRF3 missense mutations at endogenous expression levels
Li, S.; Niu, J.; Zhang, R.; Massaar, S.; Merode, J. v.; Schipper, N. d.; Kamp, L. v. d.; Peppelenbosch, M. P.; Smits, R.
10.1101/2024.03.14.585013 — cancer biology — Posted on 2024-03-18
2245 VirtuousPocketome: A Computational Tool for Screening Protein-ligand Complexes to Identify Similar Binding Sites
Pallante, L.; Cannariato, M.; Androutsos, L.; Zizzi, E. A.; Bompotas, A.; Hada, X.; Grasso, G.; Kalogeras, A.; Mavroudi, S.; Di Benedetto, G.; Theofilatos, K.; Deriu, M. A.
10.1101/2023.12.12.571207 — bioengineering — Posted on 2024-03-18
2247 The best of two worlds: using stacked generalization for integrating expert range maps in species distribution models
Oeser, J.; Zurell, D.; Mayer, F.; Coraman, E.; Toshkova, N.; Deleva, S.; Natradze, I.; Benda, P.; Ghazaryan, A.; Irmak, S.; Hasanov, N. A.; Guliyeva, G. G.; Gritsina, M.; Kuemmerle, T.
10.1101/2024.03.12.584552 — ecology — Posted on 2024-03-18
2248 Boosting the toolbox for live imaging of translation
Bellec, M.; Chen, R.; Dhayni, J.; Trullo, A.; Avinens, D.; Karaki, H.; Mazzarda, F.; Lenden-Hasse, H.; Favard, C.; Lehmann, R.; Bertrand, E.; Lagha, M.; Dufourt, J.
10.1101/2023.02.25.529998 — developmental biology — Posted on 2024-03-18
2252 The Diversified Astrocyte Developmental Programs are Modulated by Primary Ciliary Signaling
Wang, L.; Guo, Q.; Acharya, S.; Zheng, X.; Huynh, V.; Whitmore, B.; Yimit, A.; Malhotra, M.; Chatterji, S.; Rosin, N.; Labit, E.; Chipak, C.; Gorzo, K.; Haidey, J.; Elliott, D.; Ram, T.; Zhang, Q.; Kuipers, H.; Gordon, G.; Biernaskie, J.; Guo, J.
10.1101/2024.03.17.585433 — neuroscience — Posted on 2024-03-17
2253 A systems-biology approach connects aging mechanisms with Alzheimer's disease pathogenesis
Leventhal, M. J.; Zanella, C. A.; Kang, B.; Peng, J.; Gritsch, D.; Liao, Z.; Bukhari, H.; Wang, T.; Pao, P.-C.; Danquah, S.; Benetatos, J.; Nehme, R.; Farhi, S.; Tsai, L.-H.; Dong, X.; Scherzer, C.; Feany, M. B.; Fraenkel, E.
10.1101/2024.03.17.585262 — systems biology — Posted on 2024-03-17
2255 Glutamine deprivation alters TGF-β signaling in hepatocellular carcinoma
Gelabert, C.; Campisano, S.; Golan, I. C.; Beyene, N. T.; Heldin, C.-H.; Chisari, A. N.; Sancho, P.; Moustakas, A.; Caja, L.
10.1101/2024.03.17.585424 — cancer biology — Posted on 2024-03-17
2256 A deep profile of gene expression across 18 human cancers
Qiu, W.; Dincer, A. B.; Janizek, J.; Celik, S.; Pittet, M.; Naxerova, K.; Lee, S.-I.
10.1101/2024.03.17.585426 — bioinformatics — Posted on 2024-03-17
2257 Evaluating Paraspinal Muscle Response and Compensation via Musculoskeletal Modeling in Spinal Stenosis Surgeries
Jones, R.; Kumaran, Y.; Padgaonkar, A.; Hoffman, B.; Behrens, K.; Elgafy, H.; Tripathi, S.; Goel, V. K.
10.1101/2024.03.17.585440 — bioengineering — Posted on 2024-03-17
2260 A progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans
Romero-Bueno, R.; Fragoso-Luna, A.; Ayuso, C.; Kavsek, A.; Riedel, C. G.; Ward, J. D.; Askjaer, P.
10.1101/2024.03.17.585430 — cell biology — Posted on 2024-03-17
2262 Viral challenges and adaptations between Central Arctic Ocean and atmosphere
Rahlff, J.; Westmeijer, G.; Weissenbach, J.; Antson, A.; Holmfeldt, K.
10.1101/2024.03.17.584458 — microbiology — Posted on 2024-03-17
2263 Identification and characterization of neoantigen-reactive CD8+ T cells following checkpoint blockade therapy in a pan-cancer setting
Moss, K. H.; Hansen, U. K.; De Lima, V. A. B.; Borch, A.; Marquez, E. S.; Bjerregaard, A.-m.; Oestrup, O.; Bentzen, A. K.; Marquard, A. M.; Kadivar, M.; Svane, I. M.; Lassen, U.; Hadrup, S. R.
10.1101/2024.03.17.585416 — immunology — Posted on 2024-03-17
2264 Dissecting the binding mechanisms of synaptic membrane adhesion complexes using a micropattern based cellular model
Piette, N.; Strale, P.-O.; Lagardere, M.; Saphy, C.; Reissner, C.; Munier, M.; Missler, M.; Chamma, I.; Sainlos, M.; Thoumine, o.; Studer, V.
10.1101/2024.03.17.584836 — neuroscience — Posted on 2024-03-17
2266 ATF4 orchestrates IL-1α-induced senescence in adult neural stem cells
Neumann, S.; Thelin, E. P.; Sankavaram, S. R.; Persson, S.; Fonseca, L.; Moruzzi, N.; Iacobaeus, E.; Bergsland, M.; Popova, E.; Bader, M.; Svensson, M.; Espinosa, A.; Covacu, R.; Brundin, L.
10.1101/2024.03.17.585394 — neuroscience — Posted on 2024-03-17
2267 Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish
Ree, R.; Lin, S.-J.; Sti Dahl, L. O.; Huang, K.; Petree, C.; Varshney, G. K.; Arnesen, T.
10.1101/2024.03.17.585386 — biochemistry — Posted on 2024-03-17
2272 Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments
Verma, A.; Pandey, V.; Sherry, C.; James, C.; Matteson, K.; Smith, J. T.; Rudkouskaya, A.; Intes, X.; Barroso, M.
10.1101/2024.01.12.575453 — cancer biology — Posted on 2024-03-17
2277 Tuft cells act as regenerative stem cells in the human intestine
Huang, L.; Bernink, J. H.; Giladi, A.; Krueger, D.; van Son, G. J. F.; Geurts, M. H.; Busslinger, G.; Lin, L.; Zandvliet, M.; Peters, P. J.; Lopez-Iglesias, C.; Buskens, C. J.; Bemelman, W. A.; Begthel, H.; Clevers, H.
10.1101/2024.03.17.585165 — cell biology — Posted on 2024-03-17
2280 Curcumin-mediated NRF2 induction limits inflammatory damage in preclinical models of cystic fibrosis
Leon-Icaza, S. A.; Fretaud, M.; Cornelie, S.; Bureau, C.; Yatime, L.; Floto, A. R.; Renshaw, S.; Herrmann, J.-L.; Langevin, C.; Cougoule, C.; Bernut, A.
10.1101/2024.03.17.585384 — immunology — Posted on 2024-03-17
2281 The Impact of Model Assumptions in Interpreting Cell Kinetic Studies
Yan, A.; Sadreev, I.; Mackerodt, J.; Zhang, Y.; Macallan, D. C.; Busch, R.; Asquith, B.
10.1101/2024.03.17.584905 — immunology — Posted on 2024-03-17
2283 Whole-body connectome of a segmented annelid larva
Jekely, G.; Jasek, S.; Guhmann, M.; Bezares-Calderon, L. A.; Williams, E.; Shahidi, R.
10.1101/2024.03.17.585258 — neuroscience — Posted on 2024-03-17
2284 Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory
Yamawaki, N.; Login, H.; Feld-Jakobsen, S. O.; Molnar, B. M.; Kirkegaard, M. Z.; Moltesen, M.; Okrasa, A.; Radulovic, J.; Tanimura, A.
10.1101/2024.03.17.585387 — neuroscience — Posted on 2024-03-17
2285 Neurosphere culture derived from aged hippocampal dentate gyrus
Vafaeva, O.; Namchaiw, P.; Murray, K. D.; Diaz, E.; Cheng, H.-J.
10.1101/2024.03.16.585365 — neuroscience — Posted on 2024-03-17
2286 Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations
Fernandez, E. C.; Tomassoni, L.; Zhang, X.; Wang, J.; Obradovic, A.; Laise, P.; Griffin, A. T.; Vlahos, L.; Minns, H. E.; Morales, D. V.; Simmons, C.; Gallitto, M.; Wei, H.-J.; Martins, T. J.; Becker, P. S.; Crawford, J. R.; Tzaridis, T.; Wechsler-Reya, R. J.; Garvin, J.; Gartrell, R. D.; Szalontay, L.; Zacharoulis, S.; Wu, C.-C.; Zhang, Z.; Califano, A.; Pavisic, J.
10.1101/2024.03.17.585370 — systems biology — Posted on 2024-03-17
2289 D2Sim: A Computational Simulator for NanoporeSequencing based DNA Data Storage
Sankar, s.; Yixin, W.; Noor-A-Rahim, M.; Gunawan, E.; Guan, Y. L.; Poh, C. L.
10.1101/2024.03.17.585393 — bioengineering — Posted on 2024-03-17
2291 Do goldfish like to be informed?
Ajuwon, V.; Monteiro, T.; Walton, M. E.; Kacelnik, A.
10.1101/2024.03.17.585404 — animal behavior and cognition — Posted on 2024-03-17
2292 Large-scale composite hypothesis testing for omics analyses.
De Walsche, A.; Gauthier, F.; Charcosset, A.; Mary-Huard, T.
10.1101/2024.03.17.585412 — genomics — Posted on 2024-03-17
2293 Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease
Fleck, K.; Luria, V.; Garag, N.; Karger, A.; Hunter, T.; Marten, D.; Phu, W.; Nam, K.-M.; Sestan, N.; O'Donnell-Luria, A. H.; Erceg, J.
10.1101/2024.03.17.585403 — evolutionary biology — Posted on 2024-03-17
2295 Multi-omics discovery of hallmark protein and lipid features of circulating small extracellular vesicles in humans
Rai, A.; Huynh, K.; Poh, Q. H.; Fang, H.; Claridge, B.; Cross, J.; Duong, T.; Duarte, C.; Marwick, T.; Meikle, P.; Greening, D. W.
10.1101/2024.03.16.585131 — cell biology — Posted on 2024-03-17
2296 Protective function of ex vivo expanded CD8 T cells in a mouse model of adoptive therapy for cytomegalovirus infection depends on integrin beta 1 but not CXCR3, CTLA4, or PD-1 expression
Liu, X.; Gutierrez Jauregui, R.; Lueder, Y.; Halle, S.; Ospina-Quintero, L.; Ritter, C.; Schimrock, A.; Willenzon, S.; Janssen, A.; Wagner, K.; Messerle, M.; Bosnjak, B.; Foerster, R.
10.1101/2024.03.16.585350 — immunology — Posted on 2024-03-17
2298 Biomimetic fractal topography enhances podocyte maturation in vitro
Liu, C.; Aggarwal, P.; Wagner, K. T.; Landau, S. S.; Cui, T.; Song, X.; Shamaei, L.; Rafatian, N.; Zhao, Y.; Rodriguez-Ramirez, S.; Morton, K.; Virlee, E.; Li, C. Y.; Bannerman, D.; Pascual-Gil, S.; Okhovatian, S.; Radisic, A.; Clotet-Freixas, S.; Veres, T.; Sadrzadeh, M.; Filleter, T.; Broeckel, U.; Konvalinka, A.; Radisic, M.
10.1101/2024.03.16.585039 — bioengineering — Posted on 2024-03-17
2299 IMMUNOPHENOTYPING AND FUNCTIONAL ANALYSIS OF NK CELL SUBSETS IN Mycobacterium tuberculosis-INFECTED INDIVIDUALS
Silva, C. S.; Folkesson, E.; Foroogh, F.; Gower, M. S.; Kleberg, L.; Xi, P.; Sarhan, D.; Bruchfeld, J.; Correia-Neves, M.; Källenius, G.; Sundling, C.
10.1101/2024.03.16.585339 — immunology — Posted on 2024-03-17
2300 Genome-wide CRISPRa screens nominate modulators of CAR T cell survival within distinct tumor cytokine milieus
Curtis, B. C.; Spurrell, C. H.; Flint, L.; Lande, A. M.; Leonardi, M.; Rosser, J. M.; Valdez, A.; Murren, N.; Chai, T.; Fitzgerald, M.; Martinez-Reyes, J.; Saxby, C. P.; Oda, S. K.; Jensen, M. C.
10.1101/2024.03.16.583115 — immunology — Posted on 2024-03-17
2302 An arrayed CRISPR/Cas9 screen identifies mTORC1 as a regulator of lipid droplet accumulation in APOE E3 and APOE KO iPSC-derived microglia
Meier, S.; Larsen, A. S. G.; Wanke, F.; Mercado, N.; Mei, A.; Takacs, L.; Mracsko, E. S.; Collin, L.; Kampmann, M.; Roudnicky, F.; Jagasia, R.
10.1101/2024.03.16.585330 — neuroscience — Posted on 2024-03-17
2304 Naturalistic Object Representations Depend on Distance and Size Cues
Fairchild, G. T.; Holler, D. E.; Fabbri, S.; Gomez, M. A.; Walsh-Snow, J. C.
10.1101/2024.03.16.585308 — neuroscience — Posted on 2024-03-17
2307 Diclofenac-eugenol modulation of Kv7 and TRPV1 ion channels
Rivera-Ruedas, A.; Medina-Vilchis, A. R.; Romero-Tovar, J. J.; Cristobal-Mondragon, G. R.; De la Rosa, V.
10.1101/2024.03.16.585319 — physiology — Posted on 2024-03-17
2308 Conditions for the co-existence of promoter and gene-body condensates
Changiarath, A.; Michels, J.; Rodriguez, R. H.; Hanson, S. M.; Schmid, F.; Padeken, J.; Stelzl, L. S.
10.1101/2024.03.16.585180 — biophysics — Posted on 2024-03-17
2310 LIPIDS MODULATE THE DYNAMICS OF GPCR:β-ARRESTIN INTERACTION
GOMES, A. A. S.; DI MICHELE, M.; ROESSNER, R. A.; DAMIAN, M.; BISCH, P. M.; SIBILLE, N.; LOUET, M.; BANERES, J.-L.; FLOQUET, N.
10.1101/2024.03.16.585329 — biophysics — Posted on 2024-03-17
2312 ERNIE-RNA: An RNA Language Model with Structure-enhanced Representations
Yin, W.; Zhang, Z.; He, L.; Jiang, R.; Zhang, S.; Liu, G.; Zhang, X.; Qin, T.; Xie, Z.
10.1101/2024.03.17.585376 — bioinformatics — Posted on 2024-03-17
2315 Map of epigenetic age acceleration: a worldwide meta-analysis
Yusipov, I.; Kalyakulina, A.; Franceschi, C.; Ivanchenko, M.
10.1101/2024.03.17.585398 — genetics — Posted on 2024-03-17
2318 Cell culture differentiation and proliferation conditions influence the in vitro regeneration of the human airway epithelium
Redman, E.; Fierville, M.; Cavard, A.; Plaisant, M.; Arguel, M.-J.; Ruiz Garcia, S.; McAndrew, E. M.; Girard-Riboulleau, C.; Lebrigand, K.; Magnone, V.; Ponzio, G.; Gras, D.; Chanez, P.; Abelanet, S.; Barbry, P.; Marcet, B.; Zaragosi, L.-E.
10.1101/2024.03.16.584842 — cell biology — Posted on 2024-03-17
2320 Deep learning based genomic breeding of pest-resistant grapevine
Gan, Y.; Liu, Z.; Zhang, F.; Xu, Q.; Wang, X.; Xue, H.; Su, X.; Ma, W.; Long, Q.; Ma, A.; Huang, G.; Liu, W.; Xu, X.; Sun, L.; Zhang, Y.; Liu, Y.; Fang, X.; Li, C.; Yang, X.; Wei, P.; Fan, X.; Zhang, C.; Zhang, P.; Liu, C.; Zhang, Z.; Huang, S.; Wang, Y.; Liu, Z.; Zhou, Y.
10.1101/2024.03.16.585323 — plant biology — Posted on 2024-03-17
2322 Evaluation of Gene Set Enrichment Analysis (GSEA) tools highlights the value of single sample approaches over pairwise for robust biological discovery.
Bull, C.; Byrne, R. M.; Fisher, N. C.; Corry, S. M.; Amirkhah, R.; Edwards, J.; Hillson, L.; Lawler, M.; Ryan, A.; Lamrock, F.; Dunne, P. D.; Malla, S. B.
10.1101/2024.03.15.585228 — cancer biology — Posted on 2024-03-17
2323 HIV integrase compacts viral DNA into biphasic condensates
Kolbeck, P. J.; de Jager, M.; Gallano, M.; Brouns, T.; Bekaert, B.; Frederickx, W.; Konrad, S. F.; Van Belle, S.; Christ, F.; De Feyter, S.; Debyser, Z.; Filion, L. C.; Lipfert, J.; Vanderlinden, W.
10.1101/2024.03.15.585256 — biophysics — Posted on 2024-03-17
2324 Characterising tandem repeat complexities across long-read sequencing platforms with TREAT
Tesi, N.; Salazar, A.; Zhang, Y.; van der Lee, S.; Hulsman, M.; Knoop, L.; Wijesekera, S.; Krizova, J.; Schneider, A.-F.; Pennings, M.; Sleegers, K.; Kamsteeg, E.-J.; Reinders, M.; Holstege, H.
10.1101/2024.03.15.585288 — bioinformatics — Posted on 2024-03-17
2325 A Functional Map of the Human Intrinsically Disordered Proteome
Pritisanac, I.; Alderson, T. R.; Kolaric, Đesika; Zarin, T.; Xie, S.; Lu, A. X.; Alam, A.; Maqsood, A.; Youn, J.-Y.; Forman-Kay, J. D.; Moses, A. M.
10.1101/2024.03.15.585291 — bioinformatics — Posted on 2024-03-17
2327 EPA induces an anti-inflammatory transcriptomic landscape in T cells implicating a pathway independent of triglyceride lowering in CVD risk reduction
Reilly, N. A.; Dekkers, K.; Molenaar, J.; Arumugam, S.; Kuipers, T. B.; Ariyurek, Y.; Hoeksema, M. A.; Jukema, J. W.; Heijmans, B. T.
10.1101/2024.03.15.585315 — genomics — Posted on 2024-03-17
2330 Dendritic Cell - Fibroblast Crosstalk via TLR9 and AHR Signaling Drives Lung Fibrogenesis
Carter, H.; Medina Costa, R.; Bame, M.; Gilchrist, T.; Emch, C.; Adams, T.; Linderholm, A.; Oldham, J. M.; Noth, I.; Kaminski, N.; Moore, B. B.; Gurczynski, S. J.
10.1101/2024.03.15.584457 — immunology — Posted on 2024-03-17
2331 CD39 is expressed on functional effector and tissue resident memory CD8+ T cells
Isaacs, J. F.; Degefu, H. N.; Chen, T.; Kleist, S. A.; Musial, S. C.; Ford, M. A.; Searles, T. G.; Lin, C.-C.; Skorput, A. G. J.; Shirai, K.; Turk, M. J.; Zanazzi, G. J.; Rosato, P.
10.1101/2024.03.15.585252 — immunology — Posted on 2024-03-17
2332 Putaminal dopamine modulates movement motivation in Parkinson's disease
Banwinkler, M.; Dzialas, V.; Rigoux, L.; Asendorf, A.; Theis, H.; Giehl, K.; Tittgemeyer, M.; Hoenig, M.; van Eimeren, T.
10.1101/2024.03.15.585221 — neuroscience — Posted on 2024-03-17
2334 Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking
Farahbakhsh, Z. Z.; Holleran, K. M.; Sens, J. P.; Fordahl, S. C.; Mauterer, M. I.; Lopez, A. J.; Cuzon Carlson, V. C.; Kiraly, D. D.; Grant, K. A.; Jones, S. R.; Siciliano, C. A.
10.1101/2024.03.15.584711 — neuroscience — Posted on 2024-03-17
2337 Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells
Grasset, E. M.; Desphande, A.; Lee, J. W.; Cho, Y.; Shin, S. M.; Coyne, E. M.; Hernandez, A.; Yuan, X.; Cimino-Matthews, A.; Ewald, A. J.; Ho, W. J.
10.1101/2024.03.15.585195 — cancer biology — Posted on 2024-03-17
2342 Gapless assembly of complete human and plant chromosomes using only nanopore sequencing
Koren, S.; Bao, Z.; Guarracino, A.; Ou, S.; Goodwin, S.; Jenike, K. M.; Lucas, J.; McNulty, B.; Park, J.; Rautianinen, M.; Rhie, A.; Roelofs, D.; Schneiders, H.; Vrijenhoek, I.; Nijbroek, K.; Ware, D.; Schatz, M. C.; Garrison, E.; Huang, S.; McCombie, W. R.; Miga, K. H.; Wittenberg, A. H. J.; Phillippy, A. M.
10.1101/2024.03.15.585294 — bioinformatics — Posted on 2024-03-17
2347 Interpretable and predictive models to harness the life science data revolution
Jahner, J. P.; Buerkle, C. A.; Gannon, D. G.; Grames, E. M.; McFarlane, S. E.; Siefert, A.; Bell, K. L.; DeLeo, V. L.; Forister, M. L.; Harrison, J. G.; Laughlin, D. C.; Patterson, A. C.; Powers, B. F.; Werner, C. M.; Oleksy, I. A.
10.1101/2024.03.15.585297 — genomics — Posted on 2024-03-17
2348 Functional phases encode the response of the soil microbiome to environmental change
Lee, K. K.; Liu, S.; Crocker, K.; Huggins, D. R.; Tikhonov, M.; Mani, M.; Kuehn, S.
10.1101/2024.03.15.584851 — ecology — Posted on 2024-03-17
2349 Growth parameters of the clupeids Limnothrissa miodon and Stolothrissa tanganicae in northern Lake Tanganyika (Bujumbura sub-basin)
N'Sibula, M. T.; Gordo-Vilaseca, C.; Milec, L. J. M.; Patel, D. M.; Busanga, A. K.; Micha, J.-C.; Sarvala, J.; Raeymaekers, J. A. M.
10.1101/2024.03.16.584994 — ecology — Posted on 2024-03-17
2351 Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation
Roy, T.; Piplani, N.; Sthanam, L. K.; Ghosh, S.; Tiwary, N.; Dhar, S.; Konyak, W. C. W.; Panigrahi, S. S.; Singh, P.; Sowpati, D. T.; Nair, S.; Kumar, S.; Shekar, P. C.; Sen, S.
10.1101/2024.03.15.585216 — cell biology — Posted on 2024-03-17
2353 Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens
Brown, S.; Antanasijevic, A.; Sewall, L. M.; Montiel Garcia, D.; Brouwer, P. J. M.; Sanders, R. W.; Ward, A. B.
10.1101/2024.03.15.585257 — immunology — Posted on 2024-03-17
2354 Optimized CART Cell Therapy for Metastatic Aggressive Thyroid Cancer
Gleba, J. J.; Siegler, E. L.; Manriquez-Roman, C.; Huynh, T. N.; Mai, L. K.; Miller, J. L.; Miller, E. E.; Pawlush, M. L.; Alasonyalilar Demirer, A.; Kimball, B. L.; Tapper, E. E.; Sakemura, R. L.; Stewart, C. M.; Can, I.; Sirpilla, O. L.; Feigin, J. M.; Yun, K.; Gutierrez-Ruiz, O. L.; Xia, H.; Hefazi, M.; Schick, K. J.; Ogbodo, E. J.; Olivier, G.; Qiu, Y.; Tun, H. W.; Smallridge, R. C.; Zubair, A.; Copland, J. A.; Kenderian, S. S.
10.1101/2024.03.15.585286 — immunology — Posted on 2024-03-17
2355 A feedback-driven IoT microfluidic, electrophysiology, and imaging platform for brain organoid studies
Voitiuk, K.; Seiler, S. T.; Pessoa de Melo, M.; Geng, J.; Hernandez, S.; Schweiger, H. E.; Sevetson, J. L.; Parks, D. F.; Robbins, A.; Torres-Montoya, S.; Ehrlich, D.; Elliott, M. A. T.; Sharf, T.; Haussler, D.; Mostajo-Radji, M. A.; Salama, S. R.; Teodorescu, M.
10.1101/2024.03.15.585237 — neuroscience — Posted on 2024-03-17
2356 Efficiency and reliability in biological neural network architectures
Egas Santander, D.; Pokorny, C.; Ecker, A.; Lazovskis, J.; Santoro, M.; Smith, J. P.; Hess, K.; Levi, R.; Reimann, M. W.
10.1101/2024.03.15.585196 — neuroscience — Posted on 2024-03-17
2357 Lesion-remote astrocytes govern microglia-mediated white matter repair
McCallum, S.; Suresh, k. B.; Islam, T.; Saustad, A. W.; Shelest, O.; Patil, A.; Lee, D. D.; Kwon, B.; Yenokian, I.; Kawaguchi, R.; Beveridge, C. H.; Manchanda, P.; Randolph, C. E.; Meares, G. P.; Plummer, J. T.; Dutta, R.; Knott, S. R.; Chopra, G.; Burda, J. E.
10.1101/2024.03.15.585251 — neuroscience — Posted on 2024-03-17
2358 Widespread innervation of motoneurons by spinal V3 neurons globally amplifies locomotor output in mice.
Zhang, H.; Deska-Gauthier, D.; Mackay, C. S.; Hari, K.; Lucas-Osma, A. M.; Borowska-Fielding, J.; Letawsky, R. L.; Akay, T.; Fenrich, K. K.; Bennett, D. J.; Zhang, Y.
10.1101/2024.03.15.585199 — neuroscience — Posted on 2024-03-17
2360 Transcriptional modulation unique to vulnerable motor neurons predict ALS across species and SOD gene mutations
Mei, I.; Nichterwitz, S.; Leboeuf, M.; Nijssen, J.; Lenoel, I.; Repsilber, D.; Lobsiger, C. S.; Hedlund, E.
10.1101/2024.03.15.584775 — neuroscience — Posted on 2024-03-17
2361 Social state gates vision using three circuit mechanisms in Drosophila
Schretter, C. E.; Hindmarsh Sten, T.; Klapoetke, N.; Shao, M.; Nern, A.; Dreher, M.; Bushey, D.; Robie, A. A.; Taylor, A. L.; Branson, K. M.; Otopalik, A.; Ruta, V.; Rubin, G. M.
10.1101/2024.03.15.585289 — neuroscience — Posted on 2024-03-17
2362 Atypical retinal function in a mouse model of Fragile X syndrome
Vlasits, A. L.; Syeda, M.; Wickman, A.; Guzman, P.; Schmidt, T. M.
10.1101/2024.03.15.585283 — neuroscience — Posted on 2024-03-17
2363 In-gel protein digestion using acidic methanol produces a highly selective methylation of glutamic 1 acid residues.
Lozano-Prieto, M.; Camafeita, E.; Jorge, I.; Laguillo-Gomez, A.; Barrero-Rodriguez, R.; Devesa, C. A.; Pertusa, C.; Calvo, E.; Sanchez-Madrid, F.; Vazquez, J.; Martin-Cofreces, N. B.
10.1101/2024.03.15.585290 — systems biology — Posted on 2024-03-17
2365 Transcriptomic analyses in the gametophyte ofDryopteris affinis: apomixis and more
Ojosnegros, S.; Alvarez, J. M.; Gagliardini, V.; Quintanilla, L. G.; Grossniklaus, U.; Fernandez, H.
10.1101/2024.03.15.585305 — plant biology — Posted on 2024-03-17
2368 Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids
Karakulak, T.; Bolck, H. A.; Zajac, N.; Bratus-Neuenschwander, A.; Zhang, Q.; Qi, W.; Oltra, T. C.; Rehrauer, H.; von Mering, C.; Moch, H.; Kahraman, A.
10.1101/2024.03.15.585271 — cancer biology — Posted on 2024-03-17
2370 CLigOpt: Controllable Ligand Design through Target-Specific Optimisation
Li, Y.; da Costa Avelar, P. H.; Chen, X.; Zhang, L.; Wu, M.; Tsoka, S.
10.1101/2024.03.15.585255 — bioinformatics — Posted on 2024-03-17
2372 Biophysics-based protein language models for protein engineering
Gelman, S.; Johnson, B.; Freschlin, C.; D'Costa, S.; Gitter, A.; Romero, P. A.
10.1101/2024.03.15.585128 — bioinformatics — Posted on 2024-03-17
2373 Celldetective: an AI-enhanced image analysis toolfor unraveling dynamic cell interactions
Torro, R.; Diaz Bello, B.; El Arawi, D.; Ammer, L.; Chames, P.; Sengupta, K.; Limozin, L.
10.1101/2024.03.15.585250 — bioinformatics — Posted on 2024-03-17
2376 Multi-Scale Computational Model of Microvascular Remodeling in Idiopathic Pulmonary Fibrosis
Leonard-Duke, J.; Agro, S. M. J.; Csordas, D. J.; Bruce, A. C.; Eggertsen, T. G.; Tavakol, T. N.; Barker, T. H.; Bonham, C. A.; Saucerman, J. J.; Taite, L. J.; Peirce, S. M.
10.1101/2024.03.15.585249 — bioengineering — Posted on 2024-03-17
2380 Myocardin-related transcription factor drives epithelial fibrogenesis in polycystic kidney disease
Lichner, Z.; Ding, M.; Khare, T.; Dan, Q.; Benitez, R.; Praszner, M.; Song, X.; Saleeb, R.; Hinz, B.; Pei, Y.; Szaszi, K.; Kapus, A.
10.1101/2024.03.15.585204 — cell biology — Posted on 2024-03-17
2382 Caskin2 is a novel talin and Abi1-binding protein that promotes cell motility
Wang, W.; Atherton, P.; Kreft, M.; te Molder, L.; van der Poel, S.; Hoekman, L.; Celie, P.; Joosten, R. P.; Faessler, R.; Perrakis, A.; Sonnenberg, A.
10.1101/2024.03.15.585234 — cell biology — Posted on 2024-03-17
2385 Redox-dependent synaptic clustering of gephyrin
Gehling, M.-T.; Liebsch, F.; Jacobs, L.; Riemer, J.; Schwarz, G.
10.1101/2024.03.15.585209 — neuroscience — Posted on 2024-03-17
2387 Human cortical neurons rapidly generated by direct ES cell programming integrate into stroke-injured rat cortex
Martinez-Curiel, R.; Hajy, M.; Tsupykov, O.; Jansson, L.; Avaliani, N.; Coll-San Martin, B.; Monni, E.; Skibo, G.; Lindvall, O.; Palma Tortosa, S.; Kokaia, Z.
10.1101/2024.03.15.585240 — neuroscience — Posted on 2024-03-17
2388 Rat primary cortical cell tri-culture to study effects of amyloid-beta on microglia function
Kim, H.; Le, B.; Goshi, N.; Zhu, K.; Grodzki, A. C.; Lein, P. J.; Zhao, M.; Seker, E.
10.1101/2024.03.15.584736 — neuroscience — Posted on 2024-03-17
2391 Dynamics of endogenous and water cortisol release in Asian Seabass Lates calcarifer after acute stress in a farm scale recirculating aquaculture system
Tan, M. R.; Aung, K. M. M.; Salleh, N. A. b. M.; Tan, J. Y. A.; Chua, K. X.; Doblado, G. J.; Chua, K. L.; Tham, V.; Lin, J. J.; Chaganty, V.; Yusoff, D. M.; Vij, S.; Su, X.; Sutarlie, L.; Wee, C. L.
10.1101/2023.09.20.558587 — physiology — Posted on 2024-03-17
2394 Scvi-hub: an actionable repository for model-driven single cell analysis
Ergen, C.; Pour Amiri, V. V.; Kim, M.; Streets, A.; Gayoso, A.; Yosef, N.
10.1101/2024.03.01.582887 — bioinformatics — Posted on 2024-03-17
2397 Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells
Brennan, P. J.; Saunders, R. E.; Spanou, M.; Serafini, M.; Sun, L.; Heger, G. P.; Konopacka, A.; Beveridge, R. D.; Gordon, L.; Bunally, S. B.; Saudemont, A.; Benowitz, A. B.; Martinez-Fleites, C.; Queisser, M. A.; An, H.; Deane, C. M.; Hann, M. M.; Brayshaw, L. L.; Conway, S. J.
10.1101/2024.03.15.585309 — biochemistry — Posted on 2024-03-16
2398 A feedback-driven IoT microfluidic, electrophysiology, and imaging platform for brain organoid studies
Voitiuk, K.; Seiler, S. T.; Pessoa de Melo, M.; Geng, J.; Hernandez, S.; Schweiger, H. E.; Sevetson, J. L.; Parks, D. F.; Robbins, A.; Torres-Montoya, S.; Ehrlich, D.; Elliott, M. A. T.; Sharf, T.; Haussler, D.; Mostajo-Radji, M. A.; Salama, S. R.; Teodorescu, M.
10.1101/2024.03.15.585237 — neuroscience — Posted on 2024-03-17
2400 Neuronal activity promotes axonal node-like clustering prior to myelination and remyelination in the central nervous system.
Ronzano, R.; Perrot, C.; Mazuir, E.; Thetiot, M.; Aigrot, M.-S.; Stheneur, P.; Lejeune, F.-X.; Stankoff, B.; Lubetzki, C.; Sol-Foulon, N.; Desmazieres, A.
10.1101/2024.03.16.585168 — neuroscience — Posted on 2024-03-17
2401 Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data
Hall, M. B.; Wick, R. R.; Judd, L. M.; Nguyen, A. N. T.; Steinig, E. J.; Xie, O.; Davies, M. R.; Seemann, T.; Stinear, T. P.; Coin, L. J. M.
10.1101/2024.03.15.585313 — bioinformatics — Posted on 2024-03-16
2403 Structural basis for allosteric regulation of human phosphofructokinase-1
Lynch, E. M.; Hansen, H.; Salay, L. E.; Cooper, M.; Timr, S.; Kollman, J. M.; Webb, B. A.
10.1101/2024.03.15.585110 — biochemistry — Posted on 2024-03-16
2404 Protein disulfide isomerase disassembles stress granules and blocks cytoplasmic aggregation of TDP-43 in ALS
Liu, J.-Q.; Liu, H.; Li, Y.; Liu, X.; Wang, L.-Q.; Wang, K.; Yang, Z.; Fu, Q.; Xu, X.; Chen, J.; Zhang, Y.; Zhou, J.; Le, W.; Cui, M.; Liang, Y.
10.1101/2024.03.16.585334 — biochemistry — Posted on 2024-03-16
2406 Ca2+-independent ZmCPK2 is inhibited by Ca2+-dependent ZmCPK17 during drought response in maize
Hu, X.; Cheng, J.; Lu, M.; Zhu, Y.; Fang, T.; Li, Z.; Wang, X.; Wang, Y.; Guo, Y.; Yang, S.; Gong, Z.
10.1101/2024.03.15.585280 — molecular biology — Posted on 2024-03-16
2408 Alternative silencing states of Transposable Elements in Arabidopsis
Hure, V.; Piron-Prunier, F.; Yehouessi, T.; Vitte, C.; Kornienko, A. E.; Adam, G.; Nordborg, M.; Deleris, A.
10.1101/2024.03.16.585326 — molecular biology — Posted on 2024-03-16
2409 GNN codon adjacency regulates protein translation
Sun, J.; Hwang, P.; Sakkas, E. D.; Zhou, Y.; Perez, L.; Dave, I.; Kwon, J. B.; McMahon, A. E.; Wichman, M.; Raval, M.; Scopino, K.; Krizanc, D.; Thayer, K. M.; Weir, M. P.
10.1101/2024.03.16.583757 — molecular biology — Posted on 2024-03-16
2411 Wildlife as a sentinel for pathogen introduction in non-endemic areas: Is Leishmania tropica circulating in wildlife in Spain?
Azami-Conesa, I.; Matas Mendez, P.; Perez-Moreno, P.; Carrion, J.; Alunda, J. M.; Mateo Barrientos, M.; Gomez_Munoz, M. T.
10.1101/2024.03.16.585353 — microbiology — Posted on 2024-03-16
2413 Bottlenecks in the Implementation of Genome Scale Metabolic Model Based Designs for Bioproduction from Aromatic Carbon Sources
Banerjee, D.; Menasalvas, J.; Chen, Y.; Gin, J. W.; Baidoo, E. E.; Petzold, C. J.; Eng, T.; Mukhopadhyay, A.
10.1101/2024.03.15.585139 — microbiology — Posted on 2024-03-16
2414 Multiplexed screen identifies a Pseudomonas aeruginosa-specific small molecule targeting the outer membrane protein OprH and its interaction with LPS
Warrier, T.; Poulsen, B. E.; Barkho, S.; Bagnall, J.; Romano, K. P.; White, T.; Yu, X.; Kawate, T.; Nguyen, P. H.; Raines, K.; Ferrara, K.; Golas, A.; Fitzgerald, M.; Boeszoermenyi, A.; Kaushik, V.; Serrano-Wu, M.; Shoresh, N.; Hung, D. T.
10.1101/2024.03.16.585348 — microbiology — Posted on 2024-03-16
2416 AutoPeptideML: A study on how to build more trustworthy peptide bioactivity predictors
Fernandez-Diaz, R.; Cossio-Perez, R.; Agoni, C.; Hoang, L. T.; Lopez, V.; Shields, D. C.
10.1101/2023.11.13.566825 — bioinformatics — Posted on 2024-03-16
2419 The power and limits of predicting exon-exon interactions using protein 3D structures
Liebold, J.; Del Moral-Morales, A.; Manalastas-Cantos, K.; Tsoy, O.; Kurtz, S.; Baumbach, J.; Newaz, K.
10.1101/2024.03.01.582917 — bioinformatics — Posted on 2024-03-16
2420 Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference
Lobo, V.; Nowak, I.; Fernandez, C.; Correa Muler, A. I.; Westholm, J. O.; Huang, H.-C.; Fabrik, I.; Huynh, H. T.; Shcherbinina, E.; Poyraz, M.; Hartlova, A.; Benhalevy, D.; Angeletti, D.; Sarshad, A. A.
10.1101/2023.06.05.543674 — biochemistry — Posted on 2024-03-16
2423 Microbial utilisation of maize rhizodeposits applied to an agricultural soil at a range of concentrations
Niedeggen, D.; Rueger, L.; Oburger, E.; Santangeli, M.; Ahmed, M.; Vetterlein, D.; Blagodatsky, S.; Bonkowski, M.
10.1101/2024.03.15.585161 — ecology — Posted on 2024-03-16
2424 Mapping the Cellular Biogeography of Human Bone Marrow Niches Using Single-Cell Transcriptomics and Proteomic Imaging
Bandyopadhyay, S.; Duffy, M.; Ahn, K. J.; Pang, M.; Smith, D.; Duncan, G.; Sussman, J.; Zhang, J.; Huang, J.; Lin, Y. L.; Xiong, B.; Imtiaz, T.; Chen, C.-h.; Thadi, A.; Chen, C.; Xu, J.; Reichart, M.; Pillai, V.; Snaith, O.; Oldridge, D.; Bhattacharyya, S.; Maillard, I. H.; Carroll, M.; Nelson, C.; Qin, L.; Tan, K.
10.1101/2024.03.14.585083 — cell biology — Posted on 2024-03-16
2426 Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy
Zborowsky, S.; Seurat, J.; Balacheff, Q.; Minh, C. N. N.; Titecat, M.; Evrard, E.; Rodriguez-Gonzalez, R. A.; Marchi, J.; Weitz, J. S.; Debarbieux, L.
10.1101/2024.01.16.575879 — microbiology — Posted on 2024-03-16
2427 C1q/MASP complexes - hybrid complexes of classical and lectin pathway proteins are found in the circulation
Rosbjerg, A.; Plchov, T. A.; Bayarri-Olmos, R.; Holm, B. E.; Pedersen, I. S.; Skjoedt, M.-O.; Garred, P.
10.1101/2024.03.15.584944 — immunology — Posted on 2024-03-16
2429 M2M-InvNet: Human Motor Cortex Mapping from Multi-Muscle Response Using TMS and Generative 3D Convolutional Network
Akbar, M. N.; Yarossi, M.; Rampersad, S.; Lockwood, K.; Masoomi, A.; Tunik, E.; Brooks, D.; Erdogmus, D.
10.1101/2022.07.22.501062 — neuroscience — Posted on 2024-03-16
2431 Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduria
Denley, M. C. S.; Straub, M. S.; Marcionelli, G.; Güra, M. A.; Penton Ribas, D.; Delvendahl, I.; Poms, M.; Vekeriotaite, B.; Conte, F.; von Meyenn, F.; Froese, D. S.; Baumgartner, M. R.
10.1101/2024.03.15.585183 — neuroscience — Posted on 2024-03-16
2432 Corticostriatal responses to social reward are linked to trait reward sensitivity and subclinical substance use in young adults
Wyngaarden, J. B.; Johnston, C. R.; Sazhin, D.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M.; Alloy, L. B.; Smith, D. V.; Jarcho, J. M.
10.1101/2023.01.17.524305 — neuroscience — Posted on 2024-03-16
2433 Nuclear translocation of LINE-1 ORF1p alters nuclear envelope integrity and disrupts nucleocytoplasmic transport in human neurons
Znaidi, R.; Massiani-Beaudoin, O.; Mailly, P.; Monnet, H.; The Brainbank Neuro- CEB Neuropathology Network, ; Joshi, R. L.; Fuchs, J.
10.1101/2023.08.10.552479 — neuroscience — Posted on 2024-03-16
2434 Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain
Lin, Y.-H.; Wang, L.-W.; Chen, Y.-H.; Chan, Y.-C.; Hu, S.-H.; Wu, S.-Y.; Chiang, C.-S.; Huang, G.-J.; Yang, S.-D.; Chu, S.-W.; Wang, K.-C.; Lin, C.-H.; Huang, P.-H.; Cheng, H.-J.; Chen, B.-C.; Chu, L.-A.
10.1101/2022.11.28.518189 — neuroscience — Posted on 2024-03-16
2436 Thoracic epidural blockade after myocardial infarction benefits from anti-arrhythmic pathways mediated in part by parasympathetic modulation
Hoang, J. D.; Van Weperen, V. Y.; Kang, K.-W.; Jani, N.; Swid, M. A.; Chan, C. A.; Lokhandwala, Z. A.; Lux, R. L.; Vaseghi, M.
10.1101/2024.03.14.585127 — physiology — Posted on 2024-03-16
2437 Direct measurement of RNA Polymerase II hypertranscription in cancer FFPE samples
Henikoff, S.; Henikoff, J. G.; Paranal, R. M.; Greene, J. E.; Zheng, Y.; Russell, Z. R.; Szulzewsky, F.; Kugel, S.; Holland, E. C.; Ahmad, K.
10.1101/2024.02.28.582647 — cancer biology — Posted on 2024-03-16
2438 Assessing the hydromechanical control of plant growth
Laplaud, V.; Muller, E.; Demidova, N.; Drevensek, S.; Boudaoud, A.
10.1101/2023.09.21.558781 — biophysics — Posted on 2024-03-16
2441 Elongation capacity of polyunsaturated fatty acids in the annelid Platynereis dumerilii
Ramos-Llorens, M.; Bainour, K.; Adelmann, L.; Hontoria, F.; Navarro, J. C.; Raible, F.; Monroig, O.
10.1101/2024.03.15.584978 — biochemistry — Posted on 2024-03-16
2442 Aedes albopictus colonies from different geographic origins differ in their sleep and activity levels but not in the time of peak activity
Wynne, N. E.; Applebach, E.; Chandrasegaran, K.; Ajayi, O. M.; Chakraborty, S.; Bonizzoni, M.; Lahondere, C.; Benoit, J. B.; Vinauger, C.
10.1101/2024.03.15.585187 — animal behavior and cognition — Posted on 2024-03-16
2445 Analyzing bivariate cross-trait genetic architecture in GWAS summary statistics with the BIGA cloud computing platform
Li, Y.; Xue, F.; Li, B.; Yang, Y.; Fan, Z.; Shu, J.; Yang, X.; Wang, X.; Lin, J.; Copana, C.; Zhao, B.
10.1101/2023.04.28.538585 — genetics — Posted on 2024-03-16
2448 Transcriptional dynamics of the murine heart during perinatal development at single-cell resolution
Feulner, L.; Wuennemann, F.; Liang, J.; Hofmann, P.; Hitz, M.-P.; Schapiro, D.; Leclerc, S.; van Vliet, P. P.; Andelfinger, G.
10.1101/2024.03.05.583423 — developmental biology — Posted on 2024-03-16
2449 Redefining the role of Hypoxia-inducible factors (HIFs) in oxygen homeostasis
Fernandez Arias, C.; Acosta, F. J.; Bertocchini, F.; Fernandez-Arias, C.
10.1101/2024.03.15.585157 — cell biology — Posted on 2024-03-16
2451 cGAS-STING is responsible for aging of telomerase deficient zebrafish
Serifoglu, N.; Allavena, G.; Bastos-Lopes, B.; Marzullo, M.; Bousounis, P.; Trompouki, E.; Ferreira, M. G.
10.1101/2024.03.11.584360 — cell biology — Posted on 2024-03-16
2453 A Mycobacterium tuberculosis secreted virulence factor disrupts host snRNP biogenesis
Chauhan, K.; Passricha, N.; Kapoor, Y.; Datta, D.; Arora, N.; Das, M.; Rao, K.; Singh, L.; Dutt, R.; Sharma, R.; Sarkar, B.; Malakkar, B.; Saini, P.; Mehra, L.; Das, P.; Ahuja, V.; Singhal, A.; Nandicoori, V.; Kumar, D.
10.1101/2024.02.06.579120 — molecular biology — Posted on 2024-03-16
2455 The role of desmoplakin for neuronal function in the dentate gyrus and anxiety-related behavior
Otsubo, K.; Sakashita, N.; Nishimoto, Y.; Sato, Y.; Kobayashi, K.; Suzuki, K.; Segi-Nishida, E.
10.1101/2023.11.17.567646 — neuroscience — Posted on 2024-03-16
2457 Dynamin-2 Mutations Linked to Neonatal-onset Centronuclear Myopathy impair exocytosis and endocytosis in adrenal chromaffin cells.
Bayones, L.; Guerra-Fernandez, M. J.; Figuroa-Cares, C.; Gallo, L. I.; Alfonso-Bueno, S.; Baez-Matus, X.; Gonzalez-Jamett, A.; Cardenas, A. M.; Marengo, F. D.
10.1101/2024.03.07.583689 — neuroscience — Posted on 2024-03-16
2458 Correspondence of fentanyl brain pharmacokinetics and behavior measured via engineering opioids biosensors and computational ethology
Muthusamy, A. K.; Rosenberg, M.; Kim, C. H.; Wang, A. Z.; Ebisu, H.; Chin, T. M.; Koranne, A.; Marvin, J. S.; Cohen, B. N.; Looger, L. L.; Oka, Y.; Meister, M.; Lester, H. A.
10.1101/2024.03.15.584894 — neuroscience — Posted on 2024-03-16
2459 Molecular dissection of HERV-W dependent microglial- and astroglial cell polarization
Gruchot, J.; Reiche, L.; Werner, L.; Herrero, F.; Schira-Heinen, J.; Meyer, U.; Kuery, P.
10.1101/2024.03.15.584408 — neuroscience — Posted on 2024-03-16
2460 Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms
Lambourne, L.; Mattioli, K.; Santoso, C.; Sheynkman, G.; Inukai, S.; Kaundal, B.; Berenson, A.; Spirohn-Fitzgerald, K.; Bhattacharjee, A.; Rothman, E.; Shrestha, S.; Laval, F.; Yang, Z.; Bisht, D.; Sewell, J. A.; Li, G.; Prasad, A.; Phanor, S.; Lane, R.; Campbell, D. M.; Hunt, T.; Balcha, D.; Gebbia, M.; Twizere, J.-C.; Hao, T.; Frankish, A.; Riback, J.; Salomonis, N.; Calderwood, M. A.; Hill, D. E.; Sahni, N.; Vidal, M.; Bulyk, M. L.; Fuxman Bass, J. I.
10.1101/2024.03.12.584681 — systems biology — Posted on 2024-03-16
2462 Understanding the effects of oxytocin receptor variants on OXT-OXT receptor binding: A mathematical model
Dubey, P.; Fang, Y.; Tukei, K. L.; Kuila, S.; Liu, X.; Sahota, A.; Frolova, A. I.; Reinl, E. L.; Malik, M.; England, S. K.; Imoukhuede, P. I.
10.1101/2024.02.28.582600 — systems biology — Posted on 2024-03-16
2464 Postembryonic developmental roles of the Arabidopsis KEULE gene
Ruiz-Bayon, A.; Cara-Rodriguez, C.; Sarmiento-Manus, R.; Munoz-Viana, R.; Lozano, F. M.; Ponce, M. R.; Micol, J. L.
10.1101/2024.03.14.585090 — plant biology — Posted on 2024-03-16
2465 A bacterial type III effector hijacks plant ubiquitin proteases to evade degradation
Yu, W.; Li, M.; Wang, W.; Zhuang, H.; Luo, J.; Sang, Y.; Segonzac, C.; Macho, A. P.
10.1101/2024.03.15.585124 — plant biology — Posted on 2024-03-16
2466 EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas
Pollin, G.; Mathison, A.; Milech de Assuncao, T.; Thomas, A.; Zeighami, L.; Salmonson, A.; Liu, H.; Urrutia, G.; Vankayala, P.; Pandol, S. J.; Zimmermann, M. T.; Iovanna, J. L.; Jin, V. X.; Urrutia, R. A.; Lomberk, G. A.
10.1101/2024.03.14.584700 — cancer biology — Posted on 2024-03-16
2467 Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells
Berezovsky, A. D.; Nuga, O.; Datta, I.; Bergman, K.; Sabedot, T.; Gurdziel, K.; Irtenkauf, S.; Hasselbach, L.; Meng, Y.; Mueller, C.; Petricoin, E.; Brown, S.; Purandare, N.; Aras, S.; Mikkelsen, T.; Poisson, L.; Noushmehr, H.; Ruden, D. M.; deCarvalho, A.
10.1101/2024.03.14.585115 — cancer biology — Posted on 2024-03-16
2468 Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products: pH-dependent inhibition explored through computer-aided drug design.
Goyzueta Mamani, L. D.; Barazorda Ccahuana, H. L.; Candia Puma, M. A.; Sobreira Galdino, A.; Machado de Avila, R. A.; Cordeiro Giunchetti, R.; Medina Franco, J. L.; Florin Christensen, M.; Chavez Fumagalli, M. A.
10.1101/2024.03.14.585122 — bioinformatics — Posted on 2024-03-16
2473 Sparse Testing Designs for Optimizing Predictive Ability in Sugarcane Populations
Garcia-Abadillo, J.; Adunola, P.; Aguilar, F. S.; Trujillo-Montenegro, J. H.; Riascos, J. J.; Persa, R.; Isidro Y Sanchez, J.; Jarquin, D.
10.1101/2024.03.14.584687 — genomics — Posted on 2024-03-16
2475 Transposable element methylation state predicts age and disease
Morandini, F.; Lu, J. Y.; Rechsteiner, C.; Shadyab, A. H.; Casanova, R.; Snively, B.; Seluanov, A.; Gorbunova, V.
10.1101/2024.03.15.585206 — genomics — Posted on 2024-03-16
2478 Extreme temperatures impede the release success of captive-bred avian scavengers
Anglister, N.; Acacio, M.; Vaadia, G.; Arnon, E. A.; Bruer, M. B.; Hatzofe, O.; Miller, Y.; King, R.; Pinter-Wollman, N.; Spiegel, O.
10.1101/2024.03.14.585025 — ecology — Posted on 2024-03-16
2480 Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition
Edwards, C. V.; Ferri, G. M.; Villegas-Galaviz, J.; Ghosh, S.; Singh Bawa, P.; Wang, F.; Klimtchuk, E.; Ajayi, T. B.; Morgan, G. J.; Prokaeva, T.; Staron, A.; Ruberg, F. L.; Sanchorawala, V.; Giadone, R. M.; Murphy, G. J.
10.1101/2024.03.14.584987 — cell biology — Posted on 2024-03-16
2481 Development of the 12-base short dimeric myogenetic oligodeoxynucleotide that induces myogenic differentiation
Umezawa, K.; Ikeda, R.; Sakamoto, T.; Enomoto, Y.; Nihashi, Y.; Shinji, S.; Shimosato, T.; Kagami, H.; Takaya, T.
10.1101/2024.03.14.584904 — cell biology — Posted on 2024-03-16
2482 Global Release of Translational Repression Across Plasmodiums Host-to-Vector Transmission Event
Rios, K. T.; McGee, J. P.; Sebastian, A.; Moritz, R. L.; Feric, M.; Absalon, S.; Swearingen, K. E.; Lindner, S. E.
10.1101/2024.02.01.577866 — microbiology — Posted on 2024-03-16
2483 Parvalbumin interneuron mGlu5 receptors govern sex differences in prefrontal cortex physiology and binge drinking
Fabian, C. B.; Jordan, N. D.; Cole, R. H.; Carley, L. G.; Thompson, S. M.; Seney, M. L.; Joffe, M. E.
10.1101/2023.11.20.567903 — neuroscience — Posted on 2024-03-16
2488 High-throughput analysis of dendritic and axonal arbors reveals transcriptomic correlates of neuroanatomy
Gliko, O.; Mallory, M.; Dalley, R.; Gala, R.; Gornet, J.; Zeng, H.; Sorensen, S.; Sumbul, U.
10.1101/2022.03.07.482900 — neuroscience — Posted on 2024-03-16
2490 Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system.
Haun, H.; Hernandez, R.; Yan, L.; Flanigan, M.; Hon, O.; Lee, S.; Mendez, H.; Roland, A.; Taxier, L.; kash, T. L.
10.1101/2024.03.14.585116 — neuroscience — Posted on 2024-03-16
2491 Neural correlates in the time course of inferences: costs and benefits for less-skilled readers at university level.
Urrutia, M.; Pino, E.; Troncoso-Seguel, M.; Bustos, C.; Guevara, P.; Torres-Ocampo, K.; Mariangel, S.; Fu, Y.; Marrero, H.
10.1101/2024.03.14.585085 — neuroscience — Posted on 2024-03-16
2495 The transcription factor ATML1 maintains giant cell identity by inducing synthesis of its own (very) long-chain fatty acid-containing ligands
Vadde, B. V. L.; Russell, N. J.; Bagde, S. R.; Askey, B.; Saint-Antoine, M. M.; Brownfield, B. A.; Mughal, S.; Apprill, L. E.; Khosla, A.; Clark, F. K.; Schwarz, E. M.; Alseekh, S.; Fernie, A. R.; Singh, A.; Schrick, K.; Fromme, J. C.; Skirycz, A.; Formosa-Jordan, P.; Roeder, A. H. K.
10.1101/2024.03.14.584694 — plant biology — Posted on 2024-03-16
2496 Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)
Zhang, T.; Ambrodji, A.; Huang, H.; Bouchonville, K. J.; Etheridge, A. S.; Schmidt, R. E.; Bembenek, B. M.; Temesgen, Z. B.; Wang, Z.; Innocenti, F.; Stroka, D.; Diasio, R. B.; Largiader, C. R.; Offer, S. M.
10.1101/2023.11.01.565230 — pharmacology and toxicology — Posted on 2024-03-16
2497 Lack of dominant-negative activity for tumor-related ZNRF3 missense mutations at endogenous levels
Smits, R.; Li, S.; Niu, J.; Zhang, R.; Massaar, S.; Merode, J. v.; Schipper, N. d.; Kamp, L. v. d.; Peppelenbosch, M. P.
10.1101/2024.03.14.585013 — cancer biology — Posted on 2024-03-16
2498 A Novel ex-vivo platform for personalized treatment in metastatic ovarian cancer.
Valdivia, A.; Adefulajo, R. A.; Thang, M.; Cuaboy, L. A.; John, C.; Mann, B. E.; Satterlee, A. B.; Bae-Jump, V.; Hingtgen, S. D.
10.1101/2024.03.14.585117 — cancer biology — Posted on 2024-03-16
2501 Cigarette smoking drives accelerated aging across human tissues
Ramirez, J. M.; Ribeiro, R.; Soldatkina, O.; Moraes, A.; Garcia-Perez, R.; Ferreira, P. G.; Mele, M.
10.1101/2024.03.14.585016 — bioinformatics — Posted on 2024-03-16
2504 ArtiDock: fast and accurate machine learning approach to protein-ligand docking based on multimodal data augmentation
Voitsitskyi, T.; Yesylevskyy, S.; Bdzhola, V.; Stratiichuk, R.; Koleiev, I.; Ostrovsky, Z.; Vozniak, V.; Khropachov, I.; Henitsoi, P.; Popryho, L.; Zhytar, R.; Nafiiev, A.; Starosyla, S.
10.1101/2024.03.14.585019 — bioinformatics — Posted on 2024-03-16
2505 HUHgle: An Interactive Substrate Design Tool for Covalent Protein-ssDNA Labeling Using HUH-tags
Smiley, A. T.; Babilonia-Diaz, N. S.; Hughes, A. J.; Lemmex, A. C.; Anderson, M. J.; Tompkins, K. J.; Gordon, W. R.
10.1101/2024.03.15.585203 — bioinformatics — Posted on 2024-03-16
2512 Microbiome single cell atlases generated with a commercial instrument
Li, X.; Xu, L.; Demaree, B.; Noecker, C.; Bisanz, J. E.; Weisgerber, D. W.; Modavi, C.; Turnbaugh, P. J.; Abate, A. R.
10.1101/2023.08.08.551713 — bioengineering — Posted on 2024-03-16
2513 High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics
Tang, K.; Zhou, X.; Fang, S.-Y.; Vandenbulcke, E.; Du, A.; Shen, J.; Cao, H.; Zhou, J.; Chen, K.; Xin, S.; Zhou, L.; Lin, S. H.; Majety, M.; Ling, X.; Lam, S. Z.; Chow, R.; Bai, S.; Nottoli, T.; Booth, C.; Liu, C.; Dong, M. B.; Chen, S.
10.1101/2024.03.14.585126 — bioengineering — Posted on 2024-03-16
2514 In Situ-Crosslinked Zippersomes Enhance Cardiac Repair by Increasing Accumulation and Retention
Jasiewicz, N.; Mei, K.-C.; Oh, H.; Bonacquisti, E.; Chaudhari, A.; Byrum, C.; Jensen, B.; Nguyen, J.
10.1101/2024.03.14.585030 — bioengineering — Posted on 2024-03-16
2518 Post-GWAS functional analyses of CNTNAP5 suggests its role in glaucomatous neurodegeneration
Chakraborty, S.; Sarma, J.; Roy, S. S.; Mitra, S.; Bagchi, S.; Das, S.; Saha, S.; Mahapatra, S.; Bhattacharjee, S.; Maulik, M.; Acharya, M.
10.1101/2024.03.14.583830 — genetics — Posted on 2024-03-16
2519 Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps
Colinet, D.; Cavigliasso, F.; Leobold, M.; Pichon, A.; Urbach, S.; Cazes, D.; Poullet, M.; Belghazi, M.; Volkoff, A.-N.; Drezen, J.-M.; Gatti, J.-L.; Poirie, M.
10.1101/2023.06.05.543686 — evolutionary biology — Posted on 2024-03-16
2521 Multisystemic inflammatory disease in Pheasantshell (Unionidae, Actinonaias pectorosa) associated with Yokenella regensburgei infection at sites experiencing seasonal mass mortality events
Gomes Da Silva Neto, J.; Hardman, R. H.; Engman, A. C.; Dinkins, G. R.; Lane, T.; Fry, M. M.; Rines, C. R.; Bisenieks, A.; Rajeev, S.; Dennis, M. M.
10.1101/2024.03.14.585088 — ecology — Posted on 2024-03-16
2525 SYNAPTOTAGMIN-9 IN MOUSE RETINA
Mesnard, C. S.; Hays, C. L.; Townsend, L. E.; Barta, C. L.; Gurumurthy, C.; Thoreson, W. B.
10.1101/2023.06.27.546758 — neuroscience — Posted on 2024-03-16
2526 Taxonomy for human social perception
Santavirta, S.; Malen, T.; Erdemli, A.; Nummenmaa, L.
10.1101/2023.09.28.559888 — neuroscience — Posted on 2024-03-16
2527 Non-invasive optical synthetization of hearing sensation in non-genetically modified animal
Tamai, Y.; Uenaka, M.; Okamoto, A.; Hosokawa, K.; Ito, Y.; Toda, K.; Hiryu, S.; Kobayasi, K. I.
10.1101/2023.05.13.540641 — neuroscience — Posted on 2024-03-16
2528 LoCS-Net: Localizing Convolutional Spiking Neural Network for Fast Visual Place Recognition
Akcal, M. U.; Raikov, I. G.; Gribkova, E. D.; Choudhuri, A.; Soltesz, I.; Gillette, R.; Chowdhary, G.
10.1101/2024.03.14.584997 — neuroscience — Posted on 2024-03-16
2529 Surface temperatures are influenced by handling stress independently of corticosterone levels in wild king penguins (Aptenodytes patagonicus)
Lewden, A.; Ward, C.; Noiret, A.; Avril, S.; Abolivier, L.; Gerard, C.; Hammer, T. L.; Raymond, E.; Robin, J.-P.; Viblanc, V. A.; Bize, P.; STIER, A.
10.1101/2023.06.16.545254 — zoology — Posted on 2024-03-16
2530 The molecular basis of pine wilt disease resistance in Pinus massoniana
wang, j.; Cai, S.; Zeng, L.; Tong, J.; Hang, D.; Zhang, X.; Fang, Y.; Su, S.; SU, J.
10.1101/2024.03.13.584545 — plant biology — Posted on 2024-03-16
2538 First insights of the Danube sturgeon (Acipenser gueldenstaedtii) skin adherent microbiota
Matache, R.; Deak, G.; Jawdhari, A.; Sadica, I.; Pop, C.-E.; Fendrihan, S.; Craciun, N.
10.1101/2024.03.13.584882 — microbiology — Posted on 2024-03-16
2540 Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years
Bougiouri, K.; Charlton, S.; Harris, A.; Carmagnini, A.; Piliciauskiene, G.; Feuerborn, T. R.; Scarsbrook, L.; Tabadda, K.; Blazevicius, P.; Parker, H. G.; Gopalakrishnan, S.; Larson, G.; Ostrander, E. A.; Irving-Pease, E. K.; Frantz, L. A. F.; Racimo, F.
10.1101/2024.03.15.585179 — evolutionary biology — Posted on 2024-03-15
2541 OCTOPUS: Disk-based, Multiplatform, Mobile-friendly Metagenomics Classifier
Marini, S.; Barquero, A.; Wadhwani, A. A.; Bian, J.; Ruiz, J.; Boucher, C.; Prosperi, M.
10.1101/2024.03.15.585215 — molecular biology — Posted on 2024-03-15
2543 Prenatal tuning of thalamic spontaneous activity patterns regulates somatosensory map resolution
Anibal-Martinez, M.; Puche-Aroca, L.; Pumo, G.; Vandael, D.; Madrigal, M. P.; Rodriguez-Malmierca, L. M.; Valdeolmillos, M.; Martini, F. J.; Rijli, F. M.; Lopez-Bendito, G.
10.1101/2024.03.15.585193 — neuroscience — Posted on 2024-03-15
2544 Phase separation of polyubiquitinated proteins in UBQLN2 condensates controls substrate fate
Valentino, I. M.; Llivicota-Guaman, J. G.; Dao, T. P.; Mulvey, E. O.; Lehman, A. M.; Galagedera, S. K. K.; Mallon, E. L.; Castaneda, C. A.; Kraut, D. A.
10.1101/2024.03.15.585243 — biochemistry — Posted on 2024-03-15
2545 Welding PROxAb Shuttles: A modular approach for generating bispecific antibodies via site-specific protein-protein conjugation
Lehmann, T.; Schneider, H.; Tonillo, J.; Schanz, J.; Schwarz, D.; Schroeter, C.; Kolmar, H.; Hecht, S.; Anderl, J.; Rasche, N.; Rieker, M.; Dickgiesser, S.
10.1101/2024.03.15.585232 — biochemistry — Posted on 2024-03-15
2546 Non-prime- and Prime-side Profiling of Pro-Pro Endopeptidase Specificity Using Synthetic Combinatorial Peptide Libraries and Mass Spectrometry
Claushuis, B.; Cordfunke, R. A.; de Ru, A. H.; van Angeren, J.; Baumann, U.; van Veelen, P. A.; Wuhrer, M.; Corver, J.; Drijfhout, J. W.; Hensbergen, P.
10.1101/2024.03.15.585006 — molecular biology — Posted on 2024-03-15
2548 Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and fitness effects
da Trindade, N. S.; Valentini, M. B.; Rognon, A.; Mendes, T. M. F.; Allegretti, S. M.; Grunau, C.; Cabral, F. J.
10.1101/2024.03.15.585160 — molecular biology — Posted on 2024-03-15
2554 Revisiting the activity of two poly(vinyl chloride)- and polyethylene-degrading enzymes
Stepnov, A. A.; Lopez-Tavera, E.; Klauer, R.; Lincoln, C. L.; Chowreddy, R. R.; Beckham, G. T.; Eijsink, V. G. H.; Solomon, K.; Blenner, M.; Vaaje-Kolstad, G.
10.1101/2024.03.15.585159 — biochemistry — Posted on 2024-03-15
2555 R6G narrows BmrA conformational spectrum for a more efficient use of ATP
Gobet, A.; Moissonnier, L.; Zarkadas, E.; Magnard, S.; Bettler, E.; Martin, J.; Terreux, R.; Schoehn, G.; Orelle, C.; Jault, J.-M.; Falson, P.; Chaptal, v.
10.1101/2024.03.15.585201 — biochemistry — Posted on 2024-03-15
2556 Functional exploration of in vivo and in vitro lignocellulose-fed rumen bacterial microbiomes reveals novel enzymes involved in polysaccharide breakdown
Ufarte, L.; Laville, E.; Lazuka, A.; Lajus, S.; Bouhajja, E.; Cecchini, D.; Rizzo, A.; Amblard, E.; Drula, E.; Lombard, V.; Terrapon, N.; Henrissat, B.; Cleret, M.; Morgavi, D. P.; Dumon, C.; Robe, P.; Klopp, C.; Bozonnet, S.; Hernandez-Raquet, G.; Potocki-Veronese, G.
10.1101/2024.03.15.585145 — biochemistry — Posted on 2024-03-15
2558 14-3-3 binding regulates Tau assembly and microtubule association.
Hochmair, J.; van den Oetelaar, M. C. M.; Diez, L.; Lemmens, L. J. M.; Ponce, R.; Ravatt, L.; Franck, M. W.; Semenova, E.; Mohapatra, S.; Ottmann, C. O.; Brunsveld, L.; Wegmann, S.
10.1101/2024.03.15.585148 — biochemistry — Posted on 2024-03-15
2561 Emergent time scales of epistasis in protein evolution
Di Bari, L.; Bisardi, M.; Cotogno, S.; Weigt, M.; Zamponi, F.
10.1101/2024.03.14.585034 — evolutionary biology — Posted on 2024-03-15
2563 Measuring integrin force loading rates using a two-step DNA tension sensor
Combs, J. D.; Foote, A. K.; Ogasawara, H.; Velusamy, A.; Rashid, S. A.; Mancuso, J. N.; Salaita, K.
10.1101/2024.03.15.585042 — cell biology — Posted on 2024-03-15
2566 Erosion of X-Chromosome Inactivation in female hiPSCs is heterogeneous and persists during differentiation
Raposo, A. C.; Caldas, P.; Arez, M.; Jeremias, J.; Barbosa, P.; Sousa-Luis, R.; Agua, F. D.; Oxley, D.; Mupo, A. M.; Eckersley-Maslin, M.; Casanova, M.; Grosso, A. R.; da Rocha, S. T.
10.1101/2024.03.15.585169 — molecular biology — Posted on 2024-03-15
2570 A Preliminary list of Birds from Laguna de Matusagarati: A Wildlife Refuge in Darien Province, Panama
Garzon, J. L.; Pimentel, G.; Carrera, J. P.; Valderrama, A.; Alfaro, Y.; Medina, J. L.; Castillero, P.
10.1101/2024.03.14.585043 — zoology — Posted on 2024-03-15
2571 Late Miocene transformation of Mediterranean Sea biodiversity
Agiadi, K.; Hohmann, N.; Gliozzi, E.; Thivaiou, D.; Bosellini, F.; Taviani, M.; Bianucci, G.; Collareta, A.; Londeix, L.; Faranda, C.; Bulian, F.; Koskeridou, E.; Lozar, F.; Mancini, A. M.; Dominici, S.; Moissette, P.; Campos, I. B.; Borghi, E.; Iliopoulos, G.; Antonarakou, A.; Kontakiotis, G.; Besiou, E.; Zarkogiannis, S. D.; Harzhauser, M.; Sierro, F. J.; Coll, M.; Vasiliev, I.; Camerlenghi, A.; Garcia-Castellanos, D.
10.1101/2024.03.14.585031 — paleontology — Posted on 2024-03-15
2572 Data Imbalance in Drug Response Prediction - Multi-Objective Optimization Approach in Deep Learning Setting
Narykov, O.; Zhu, Y.; Brettin, T.; Evrard, Y. A.; Partin, A.; Xia, F.; Shukla, M.; Vasanthakumari, P.; Doroshow, J. H.; Stevens, R. L.
10.1101/2024.03.14.585074 — cancer biology — Posted on 2024-03-15
2573 Single cell view of tumor microenvironment gradients in pleural mesothelioma
Giotti, B.; Dolasia, K.; Zhao, w.; Cai, P.; Sweeney, R.; Merritt, E.; Kiner, E.; Kim, G.; Bhagwat, A.; Hegde, S.; Fitzgerald, B.; Shroff, S.; Dawson, T.; Garcia-Barros, M.; Abdul-Ghafar, J.; Chen, R.; Gnjatic, S.; Soto, A.; Brody, R.; Kim-Schulze, S.; Chen, Z.; Beaumont, K. G.; Merad, M.; Flores, R.; Sebra, R.; horowitz, a.; Marron, T. U.; Tocheva, A.; Wolf, A.; Tsankov, A.
10.1101/2024.03.14.585048 — cancer biology — Posted on 2024-03-15
2578 SegmentNT: annotating the genome at single-nucleotide resolution with DNA foundation models
de Almeida, B. P.; Dalla-Torre, H.; Richard, G.; Blum, C.; Hexemer, L.; Gelard, M.; Pandey, P.; Laurent, S.; Laterre, A.; Lang, M.; Sahin, U.; Beguir, K.; Pierrot, T.
10.1101/2024.03.14.584712 — genomics — Posted on 2024-03-15
2579 Olfaction in Tephritidae: a balance between detection and discrimination
Ramiaranjatovo, G.; Charlery de la Masseliere, M.; Dekker, T.; Duyck, P.-F.; Larsson Herrera, S.; Reynaud, B.; Jacob, V.
10.1101/2024.03.14.584788 — ecology — Posted on 2024-03-15
2580 Generation of densely labeled oligonucleotides for the detection of small genomic elements
Steinek, C.; Guirao Ortiz, M.; Stumberger, G.; Toelke, A. J.; Hoerl, D.; Carell, T.; Harz, H.; Leonhardt, H.
10.1101/2024.03.15.583980 — cell biology — Posted on 2024-03-15
2585 Common soil history is more important than plant history for arbuscular mycorrhizal community assembly in an experimental grassland diversity gradient
Albracht, C.; Solbach, M. D.; Hennecke, J.; Bassi, L.; van der Ploeg, G. R.; Eisenhauer, N.; Weigelt, A.; Buscot, F.; Heintz-Buschart, A.
10.1101/2024.03.14.585138 — microbiology — Posted on 2024-03-15
2587 Clostridium innocuum, an opportunistic gut pathogen, inactivates host gut progesterone and arrests ovarian follicular development
Chen, M.-J.; Chou, C.-H.; Hsiao, T.-H.; Wu, T.-Y.; Li, C.-Y.; Chen, Y.-L.; Chao, K.-H.; Lee, T.-H.; Gicana, R.; Shih, C.-J.; Brandon-Mong, G.-J.; Lai, Y.-L.; Li, P.-T.; Tseng, Y.-L.; Wang, P.-H.; Chiang, Y.-R.
10.1101/2024.03.15.585140 — microbiology — Posted on 2024-03-15
2588 Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity
Luo, X.; McAndrews, K. M.; Arian, K. A.; Morse, S. J.; Boeker, V.; Kumbhar, S. V.; Hu, Y.; Mahadevan, K. K.; Church, K. A.; Chitta, S.; Ryujin, N. T.; Hensel, J.; Dai, J.; Dowlatshahi, D. P.; Sugimoto, H.; Kirtley, M. L.; LeBleu, V. S.; Shalapour, S.; Simmons, J. H.; Kalluri, R.
10.1101/2024.03.14.585062 — immunology — Posted on 2024-03-15
2594 de Novo Sequencing of Antibodies for Identification of Neutralizing Antibodies in Human Plasma Post SARS-CoV-2 Vaccination
Le Bihan, T.; Nunez de Villavicencio Diaz, T.; Reitzel, C.; Lange, V.; Park, M.; Beadle, E. M.; Wu, L.; Jovic, M.; Dubois, R. M.; Couzens, A. L.; Duan, J.; Han, X.; Liu, Q.; Ma, B.
10.1101/2024.03.14.583523 — immunology — Posted on 2024-03-15
2595 Simultaneous and Dynamic Super-Resolution Imaging of Two Proteins in Arabidopsis thaliana using dual-color sptPALM
Rohr, L.; Ehinger, A.; Burmeister, N. G.; Meixner, A. J.; Kemmerling, B.; Harter, K.; zur Oven-Krockhaus, S.
10.1101/2024.03.13.584811 — plant biology — Posted on 2024-03-15
2597 Construction of an Immunoinformatics-Based Multi-Epitope Vaccine Candidate targeting Kyasanur Forest Disease Virus
Manjari, S.; Rajan, L. S.; Shete, A. M.; Jani, V.; Patil, S.; Joshi, Y.; Sahay, R. R.; Patil, D. Y.; Mohandas, S.; Majumdar, T.; Sonavane, U.; Joshi, R.; Yadav, P.
10.1101/2024.03.14.584963 — bioinformatics — Posted on 2024-03-15
2599 Comparison of Single-cell Long-read and Short-read Transcriptome Sequencing of Patient-derived Organoid Cells of ccRCC: Quality Evaluation of the MAS-ISO-seq Approach
Zajac, N.; Zhang, Q.; Bratus-Neuenschwander, A.; Qi, W.; Bolck, H. A.; Karakulak, T.; Carrasco Oltra, T.; Moch, H.; Kahraman, A.; Rehrauer, H.
10.1101/2024.03.14.584953 — genomics — Posted on 2024-03-15
2601 Dynamic fibroblast-immune interactions shape wound healing after brain injury
Ewing-Crystal, N. A.; Mroz, N. M.; Chang, A. A.; Merrill, E. D.; Caryotakis, S. E.; Teo, L.; Larpthaveesarp, A.; Tsukui, T.; Katewa, A.; Pennington, R.; McKinsey, G. L.; Nelson, S.; Ciesielska, A.; Dahlgren, M. W.; Paidassi, H.; Jain, S.; Aghi, M. K.; Bourne, J. A.; Paz, J. T.; Gonzalez, F. F.; Sheppard, D.; Molofsky, A. V.; Arnold, T. D.; Molofsky, A. B.
10.1101/2024.03.13.584873 — immunology — Posted on 2024-03-15
2602 A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virus
Lin, X.; Wang, J.; Ling, S.; Xiao, C.; Liang, Z.; Chow, C. L.; Yang, B.; Xiao, B.; Cowling, B. J.; Webby, R. J.; Zanin, M.; Wong, S.-S.
10.1101/2024.03.14.584765 — immunology — Posted on 2024-03-15
2603 A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling
Curren, B.; Ahmed, T.; Rashid, R. B.; Sebina, I.; Sikder, M. A. A.; Howard, D. R.; Alorro, M.; Ullah, M. A.; Bissell, A.; Rahman, M. M.; Pearen, M. A.; Ramm, G. A.; Varelias, A.; Rose-John, S.; Cuiv, P. O.; Spann, K. M.; Dennis, P. G.; Phipps, S.
10.1101/2024.03.13.584927 — immunology — Posted on 2024-03-15
2607 A distinctive tumor compartment in pancreatic lobules defined by nascent stroma and classical tumor cell phenotype
Söderqvist, S. I. M.; Viljamaa, A.; Geyer, N.; Strell, C.; Hekmati, N.; Engstrand, J.; Sparrelid, E.; Salmen, C.; Heuchel, R. L.; Zacharouli, A.; Ghorbani, P.; Harrizi, S.; Hamidi, Y.; Khorosjutina, O.; Milanova, S.; Schmierer, B.; Bozoky, B.; Moro, C. F.; Gerling, M.
10.1101/2024.03.14.584614 — cancer biology — Posted on 2024-03-15
2608 Metabolic Reprogramming by Mutant GNAS Creates an Actionable Dependency in Intraductal Papillary Mucinous Neoplasms of the Pancreas
Makino, Y.; Rajapakshe, K. I.; Selvanesan, B. C.; Okumura, T.; Date, K.; Dutta, P.; Abou-Elkacem, L.; Sagara, A.; Min, J.; Sans, M.; Yee, N.; Siemann, M. J.; Enriquez, J.; Smith, P.; Bhattacharya, P.; Kim, M.; Dede, M.; Hart, T.; Maitra, A.; Thege, F. I.
10.1101/2024.03.13.584524 — cancer biology — Posted on 2024-03-15
2611 Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations.
Kumawat, A.; Tavazzani, E.; Lentini, G.; Trancuccio, A.; Kukavica, D.; Denegri, M.; Priori, S. G.; Camilloni, C.
10.1101/2024.03.13.584147 — biophysics — Posted on 2024-03-15
2612 How motility drives the glassy dynamics in confluent epithelial monolayers?
Sadhukhan, S.; Nandi, M. K.; Pandey, S.; Paoluzzi, M.; Dasgupta, C.; Gov, N.; Nandi, S. K.
10.1101/2024.03.14.584932 — biophysics — Posted on 2024-03-15
2613 Lipophilic compounds restore wt function of neurodevelopmental-associated KCNQ3 mutations.
Edmond, M. A.; Hinojo-Perez, A.; Efrem, M.; Lin, Y.-C.; Shams, I.; Hayoz, S.; de la Cruz, A.; rodriguez, M. E. P.; Diaz-Solares, M.; Dykxhoorn, D. M.; Luo, Y.; Soria, R. B.
10.1101/2024.03.13.584879 — biophysics — Posted on 2024-03-15
2616 A sensorimotor enhanced neuromusculoskeletal model for simulating postural control of upright standing
Shanbhag, J.; Fleischmann, S.; Wechsler, I.; Gassner, H.; Winkler, J.; Eskofier, B. M.; Koelewijn, A. D.; Wartzack, S.; Miehling, J.
10.1101/2024.03.13.584822 — bioengineering — Posted on 2024-03-15
2617 Intra-Lymph Node Crosslinking of Antigen-Bearing Polymers Enhances Humoral Immunity and Dendritic Cell Activation
Euliano, E. M.; Agrawal, A.; Yu, M. H.; Graf, T. P.; Henrich, E. M.; Kunkel, A. A.; McHugh, K. J.
10.1101/2024.03.13.584831 — bioengineering — Posted on 2024-03-15
2622 Haplore: An alternative approach for Y chromosomal haplogroup identification
Laoprapaipan, L.; Phusawang, K.; Laorchairangsi, P.; Kitnitchee, A.; Wachirawanitchkit, H.; Suwanparsert, B.; Promnun, P.
10.1101/2024.03.13.584919 — evolutionary biology — Posted on 2024-03-15
2623 The host genotype actively shapes its microbiome across generations
Benga, L.; Rehm, A.; Gougoula, C.; Westhoff, P.; Wachtmeister, T.; Benten, W. P. M.; Engelhardt, E.; Weber, A. P. M.; Koehrer, K.; Sager, M.; Janssen, S.
10.1101/2024.03.14.584950 — ecology — Posted on 2024-03-15
2624 Rust Fungus Red Data List and Census Catalogue for Wales
Woods, R. G.; Stringer, R. N.; Evans, D. A.; Chater, A. O.
10.1101/2024.03.13.582811 — microbiology — Posted on 2024-03-15
2629 Strategies for Inducing and Validating Zinc Deficiency and Zinc Repletion
Wenegieme, T.-Y.; Elased, D.; Rockwood, J.; Hasrat, K.; McMichael, K.; Marshall, A.; Neikirk, K.; Kirabo, A.; Elased, K.; Hinton, A.; Williams, C. R.
10.1101/2024.02.28.582542 — physiology — Posted on 2024-03-15
2630 SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion
Zhang, J.; Kennedy, A.; de Melo Jorge, D. M.; Xing, L.; Reid, W.; Bui, S.; Joppich, J.; Rose, M.; Ercan, S.; Tang, Q.; Tai, A. W.; Wang, Y.
10.1101/2022.03.04.483074 — cell biology — Posted on 2024-03-15
2634 Deep super-resolution imaging of thick tissue using structured illumination with adaptive optics
Wang, J.; Stoychev, D.; Phillips, M.; Pinto, D. M. S.; Parton, R. M.; Hall, N.; Titlow, J.; Faria, A. R.; Wincott, M.; Gala, D.; Gerondopoulos, A.; Irani, N.; Dobbie, I.; Schermelleh, L.; Booth, M.; Davis, I.
10.1101/2023.12.21.572818 — cell biology — Posted on 2024-03-15
2637 Dynamic Network Analysis of Electrophysiological Task Data
Gohil, C.; Kohl, O.; Huang, R.; van Es, M. W. J.; Parker Jones, O.; Hunt, L. T.; Quinn, A. J.; Woolrich, M. W.
10.1101/2024.01.12.567026 — neuroscience — Posted on 2024-03-15
2640 Non-Gaussian Normative Modelling With Hierarchical Bayesian Regression
de Boer, S. A. A.; Bayer, J.; Kia, S. M.; Rutherford, S.; Zabihi, M.; Fraza, C.; Barkema, P.; Westlye, L. T.; Andreassen, O.; Hinne, M.; Beckmann, C. F.; Marquand, A. F.
10.1101/2022.10.05.510988 — neuroscience — Posted on 2024-03-15
2643 Genome sequences of four Ixodes species expands understanding of tick evolution
Cerqueira de Araujo, A.; Noel, B.; Bretaudeau, A.; Labadie, K.; Boudet, M.; Tadrent, N.; Istace, B.; Kritli, S.; Cruaud, C.; Olaso, R.; Deleuze, J.-F.; Voordouw, M.; Hervet, C.; Plantard, O.; Zamoto-Niikura, A.; Chertemps, T.; Maibeche, M.; Hilliou, F.; Le Goff, G.; Kopacek, P.; Perner, J.; Chmelar, J.; Mazak, V.; Jmel, M. A.; Kotsyfakis, M.; Medina, J. M.; Hackenberg, M.; Simo, L.; Koutroumpa, F. A.; Wincker, P.; Aury, J.-M.; Rispe, C.
10.1101/2024.02.29.581698 — genomics — Posted on 2024-03-15
2644 Socioecological drivers of injuries in female and male rhesus macaques (Macaca mulatta)
Pavez Fox, M. A.; Siracusa, E.; Ellis, S.; Kimock, C.; Rivera-Barreto, N.; Negron-Del Valle, J.; Phillips, D.; Ruiz-Lambides, A.; Snyder-Mackler, N.; Higham, J.; Brent, L.; De Moor, D.
10.1101/2023.10.20.563310 — evolutionary biology — Posted on 2024-03-15
2645 Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons
Jones, A. G.; Schaal, G.; Boye, A.; Creemers, M.; Derolez, V.; Desroy, N.; Fiandrino, A.; Mouton, T. L.; Simier, M.; Smith, N.; Ouisse, V.
10.1101/2022.08.18.504439 — ecology — Posted on 2024-03-15
2648 A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria Framework
Quah, S. K. L.; Jo, B.; Geniesse, C.; Uddin, L. Q.; Mumford, J. A.; Barch, D. M.; Fair, D. A.; Gotlib, I. H.; Poldrack, R. A.; Saggar, M.
10.1101/2024.01.31.577486 — neuroscience — Posted on 2024-03-15
2654 Heparan sulfate dependent phase separation of CCL5 and its chemotactic activity
Yu, X.; Duan, G.; Pei, P.; Chen, L.; Gu, R.; Hu, W.; Zhang, H.; Wang, Y.-D.; Gong, L.; Liu, L.; Chu, T.-T.; Li, J.-P.; Luo, S.-Z.
10.1101/2023.11.15.567182 — cell biology — Posted on 2024-03-15
2655 Microbial nitrogen guilds in the oceans: from the bathypelagic to the ocean surface
Rivas-Santisteban, J.; Fernandez-Gonzalez, N.; Laso-Perez, R.; Tamames, J.; Pedros-Alio, C.
10.1101/2024.03.05.583471 — microbiology — Posted on 2024-03-15
2656 Memory reactivation during sleep does not act holistically on object memory
Siefert, E. M.; Uppuluri, S.; Mu, J.; Tandoc, M. C.; Antony, J. W.; Schapiro, A. C.
10.1101/2023.12.14.571683 — neuroscience — Posted on 2024-03-15
2659 Using behavioral biomarkers to redefine epochs of spontaneous recovery following spinal cord injury
Eisdorfer, J. T.; Thackray, J. K.; Theis, T.; Vivinetto, A.; Ricci, M. T.; Lin, S.; Oputa, O.; Martinez, A. M.; Nacht, H. D.; Tschang, M.; Mahmood, M.; Tucker, A.; Ruven, C.; Bohic, M.; Pusuloori, S.; Zmoyro, L.; Kumar, S.; Abraira Lab Computational Group, ; Schachner, M.; Sahni, V.; Popovich, P.; Ferguson, A. R.; McTigue, D.; Tysseling, V. M.; Dulin, J.; Hollis, E.; Datta, S. R.; Abraira, V. E. G.
10.1101/2023.10.31.564826 — neuroscience — Posted on 2024-03-15
2660 Group-common and individual-specific effects of structure-function coupling in human brain networks with graph neural networks
Chen, P.; Yang, H.; Zheng, X.; Jia, H.; Hao, J.; Xu, X.; Li, C.; He, X.; Chen, R.; Okubo, T. S.; Cui, Z.
10.1101/2023.11.22.568257 — neuroscience — Posted on 2024-03-15
2661 Reliability of brain metrics derived from a Time-Domain Functional Near-Infrared Spectroscopy System
Dubois, J.; Field, R. M.; Jawhar, S.; Koch, E. M.; Aghajan, Z. M.; Miller, N.; Perdue, K. L.; Taylor, M.
10.1101/2024.03.12.584660 — neuroscience — Posted on 2024-03-15
2662 Gene expression shifts in Emperor penguin adaptation to the extreme Antarctic environment
Paris, J. R.; Fernandes, F. A. N.; Pirri, F.; Greco, S.; Gerdol, M.; Pallavicini, A.; Benoiste, M.; Cornec, C.; Zane, L.; Haas, B.; Le Bohec, C.; Trucchi, E.
10.1101/2023.11.29.569211 — evolutionary biology — Posted on 2024-03-15
2664 Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism
Arbogast, F.; Sal-Carro, R.; Boufenghour, W.; Frenger, Q.; Bouis, D.; Filippi de la Palavesa, L.; Fauny, J.-D.; Griso, O.; Puccio, H.; Fima, R.; Huby, T.; Gautier, E. L.; Molitor, A.; Carapito, R.; Bahram, S.; Romani, N.; Clausen, B. E.; Voisin, B.; Mueller, C. G.; Gros, F.; Flacher, V.
10.1101/2022.09.16.507799 — immunology — Posted on 2024-03-15
2666 Sparse-Coding Variational Auto-Encoders
Geadah, V.; Barello, G.; Charles, A.; Pillow, J.
10.1101/399246 — neuroscience — Posted on 2024-03-15
2671 Urban birds' tolerance towards humans was largely unaffected by increased variation in human levels due to COVID-19 shutdowns
Mikula, P.; Bulla, M.; Blumstein, D.; Benedetti, Y.; Floigl, K.; Jokimaki, J.; Kaisanlahti-Jokimaki, M.-L.; Marko, G.; Morelli, F.; Moller, A. P.; Siretckaia, A.; Szakony, S.; Weston, M.; Zeid, F. A.; Tryjanowski, P.; Albrecht, T.
10.1101/2022.07.15.500232 — animal behavior and cognition — Posted on 2024-03-15
2672 Gene expression signatures of response to fluoxetine treatment: systematic review and meta-analyses
Cooper, D. G.; Cowden, J. P.; Stanley, P. A.; Karbowski, J. T.; Gaertig, V. S.; Lukan, C. J.; Vo, P. M.; Worthington, A. D.; Class, C. A.
10.1101/2024.02.19.581045 — genomics — Posted on 2024-03-15
2673 Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes
Joshi, J. N.; Changela, N.; Mahal, L.; Defosse, T.; McKim, J. K.; Wang, L.-I.; Das, A.; Shapiro, J. G.; McKim, K.
10.1101/2024.03.14.585003 — genetics — Posted on 2024-03-14
2676 FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans
Kimmich, M. J.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.
10.1101/2024.02.29.582848 — cell biology — Posted on 2024-03-15
2677 The polarity protein Yurt associates with the plasma membrane via basic and hydrophobic motifs embedded in its FERM domain
Gamblin, C. L.; Alende, C.; Corriveau, F.; Jette, A.; Parent-Prevost, F.; Biehler, C.; Majeau, N.; Laurin, M.; Laprise, P.
10.1101/2023.09.28.559937 — cell biology — Posted on 2024-03-15
2678 The Dystrophin-Dystroglycan complex ensures cytokinesis efficiency in Drosophila epithelia
Goncalves, M.; Lopes, C.; Alegot, H.; Osswald, M.; Bosveld, F.; Ramos, C.; Richard, G.; Bellaiche, Y.; Mirouse, V.; Morais-de-Sa, E.
10.1101/2024.03.14.585005 — cell biology — Posted on 2024-03-14
2679 A small molecule inhibitor Mirin prevents TOP3A-dependent mtDNA breakage and segregation
Aasumets, K.; Hangas, A.; Bader, C. P. J.; Erdinc, D.; Wanrooij, S.; Wanrooij, P. H.; Goffart, S.; Pohjoismaki, J. L. O.
10.1101/2024.03.14.585071 — molecular biology — Posted on 2024-03-14
2680 Structures of transcription-translation coupling complexes at each stage of the translation cycle
Zhang, J.; Lu, G.; Zhou, W.; Yang, M.; Li, L.; Shao, H.; Zhou, X.; Chen, C.; Gao, Y.; Ebright, R. H.; Lin, J.; Wang, C.
10.1101/2024.03.13.584796 — molecular biology — Posted on 2024-03-14
2681 The specific AMPK activator A-769662 ameliorates pathological phenotypes following mitochondrial DNA depletion
Carvalho, G.; Repoles, B.; Nguyen, T. V. H.; Forslund, J. M. E.; Ranjbarian, F.; Mendes, I. C.; Falabella, M.; Doimo, M.; Wanrooij, S.; Pitceathly, R. D.; Hofer, A.; Wanrooij, P. H.
10.1101/2024.03.14.584413 — molecular biology — Posted on 2024-03-14
2682 Early life stress-induced miR-708-5p affects bipolar disorder-associated phenotypes through neuronatin downregulation
Gilardi, C.; Martins, H. C.; Lo Bianco, A.; Bicker, S.; Germain, P.-L.; Gross, F.; Sungur, A. O.; Kisko, T.; Stein, F.; Meinert, S.; Woehr, M.; Schwarting, R. K.; Dannlowski, U.; Kircher, T.; Schratt, G.
10.1101/2024.03.14.584977 — neuroscience — Posted on 2024-03-14
2684 CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma
Saba, K. H.; Difilippo, V.; Styring, E.; Nilsson, J.; Magnusson, L.; van den Bos, H.; Spierings, D. C. J.; Foijer, F.; Nathrath, M.; Haglund de Flon, F.; Baumhoer, D.; Nord, K. H.
10.1101/2024.03.13.584810 — cancer biology — Posted on 2024-03-14
2686 H3-OPT: Accurate prediction of CDR-H3 loop structures of antibodies with deep learning
Tian, B.; Chen, H.; Fan, X.; Zhu, S.; Pei, Y.; Zhang, X.; Zhang, X.; Liu, L.; Qian, F.
10.1101/2023.08.19.553933 — bioinformatics — Posted on 2024-03-14
2692 Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo
Dennis, T. P. W.; Pescod, P.; Barasa, S.; Cerdeira, L. T.; Lucas, E. R.; Clarkson, C. S.; Miles, A.; Asidi, A.; Manzambi, E. Z.; Metelo, E.; Zanga, J.; Salambi, S. N.; Irish, S. R.; Donnelly, M. J.; Weetman, D.; Tezzo, F. W.
10.1101/2024.03.12.584605 — evolutionary biology — Posted on 2024-03-14
2693 Czech Republic butterfly barcoding reveals that distribution of genetic lineages depends on species traits
Suchackova Bartonova, A.; Skopek, P.; Konvicka, M.; Benes, J.; Spitzer, L.; Sbaraglia, C.; Vrabec, V.; Papp Maresova, J.; Konvickova, H.; Faltynek Fric, Z.
10.1101/2024.01.17.576072 — ecology — Posted on 2024-03-14
2697 Enhanced mucosal mitochondrial function corrects dysbiosis and OXPHOS metabolism in IBD
Kapur, N.; Alam, A.; Hassan, S. A.; Patel, P. H.; Wempe, L.; Bhogoju, S.; Goretsky, T.; Kim, J. H.; Herzog, J.; Ge, Y.; Awuah, S.; Byndloss, M.; Baumler, A. J.; Zadeh, M.; Sator, R. B.; Barrett, T. A.
10.1101/2024.03.14.584471 — molecular biology — Posted on 2024-03-14
2700 Identification of a new family of peptidoglycan transpeptidases reveals atypical crosslinking is essential for viability in Clostridioides difficile
Bollinger, K. W.; Muh, U.; Ocius, K. L.; Apostolos, A. J.; Pires, M. M.; Helm, R. F.; Popham, D. L.; Weiss, D. S.; Ellermeier, C. D.
10.1101/2024.03.14.584917 — microbiology — Posted on 2024-03-14
2704 A random mutagenesis screen enriched for missense mutations in bacterial effector proteins.
Urbanus, M. L.; Zheng, T. M.; Khusnutdinova, A. N.; Banh, D.; Mount, H. O.; Gupta, A.; Stogios, P. J.; Savchenko, A.; Isberg, R. R.; Yakunin, A. F.; Ensminger, A. W.
10.1101/2024.03.14.585084 — microbiology — Posted on 2024-03-14
2705 The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors
Wagner, S.; Malmsheimer, S.; Grin, I.; Bohn, E.; Franz-Wachtel, M.; Macek, B.; Sahr, T.; Smollich, F.; Chetrit, D.; Meir, A.; Roy, C.; Buchrieser, C.
10.1101/2024.03.14.584949 — microbiology — Posted on 2024-03-14
2706 Assessing fecal metaproteomics workflow and small protein recovery using DDA and DIA PASEF mass spectrometry
Wang, A.; Fekete, E. E.; Creskey, M.; Cheng, K.; Ning, Z.; Pfeifle, A.; Li, X.; Figeys, D.; Zhang, X.
10.1101/2024.03.13.584844 — microbiology — Posted on 2024-03-14
2707 A Toolbox for Neisseria meningitidis: Gene Editing, Complementation and Labelling
Wuckelt, M.; Laurent, A.; Mouville, C.; Meyer, J.; Jamet, A.; Lecuyer, H.; Nassif, X.; Bille, E.; Pelicic, V.; Coureuil, M.
10.1101/2024.03.14.585072 — microbiology — Posted on 2024-03-14
2708 Expanding the human gut microbiome atlas of Africa
Maghini, D. G.; Oduaran, O. H.; Wirbel, J.; Ingasia Olubayo, L. A.; Smyth, N.; Mathema, T.; Belger, C. W.; Agongo, G.; Boua, P. R.; Choma, S. S.; Gomez-Olive, F. X.; Kisiangani, I.; Mashaba, G. R.; Micklesfield, L.; Mohamed, S. F.; Nonterah, E. A.; Norris, S.; Sorgho, H.; Tollman, S.; Wafawanaka, F.; Tluway, F.; Ramsay, M.; Bhatt, A. S.; Hazelhurst, S.
10.1101/2024.03.13.584859 — microbiology — Posted on 2024-03-14
2709 Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV
Chao, C. W.; Sprouse, K. R.; Miranda, M. C.; Catanzaro, N. J.; Hubbard, M. L.; Addetia, A.; Stewart, C.; Brown, J. T.; Dosey, A.; Valdez, A.; Ravichandran, R.; Hendricks, G. G.; Ahlrichs, M.; Dobbins, C.; Hand, A.; Treichel, C.; Willoughby, I.; Walls, A. C.; McGuire, A. T.; Leaf, E. M.; Baric, R. S.; Schaefer, A.; Veesler, D.; King, N. P.
10.1101/2024.03.13.584735 — immunology — Posted on 2024-03-14
2711 Exploring working memory updating processes of the human subcortex using 7T MRI
Trutti, A. C.; Sjoerds, Z.; Boag, R. J.; Walstra, S. L.; Miletic, S.; Isherwood, S. J.; Bazin, P.-L.; Hommel, B.; Habli, S.; Tse, D.; Haberg, A. K.; Forstmann, B. U.
10.1101/2024.03.14.584970 — neuroscience — Posted on 2024-03-14
2713 Inhibition of Acyl-CoA Synthetase Long Chain Isozymes Decreases Multiple Myeloma Cell Proliferation and Causes Mitochondrial Dysfunction
Murphy, C. S.; DeMambro, V. E.; Fadel, S.; Fairfield, H.; Garter, C. A.; Rodriguez, P.; Qiang, Y.-W.; Vary, C. P. H.; Reagan, M. R.
10.1101/2024.03.13.583708 — cancer biology — Posted on 2024-03-14
2716 Slippery sequences stall the 26S proteasome at multiple points along the translocation pathway
Ragwan, E. R.; Kisker, F. M.; Mornin, A. R.; Weiser, K. R.; Lago, A. V.; Kraut, D. A.
10.1101/2024.03.14.584990 — biochemistry — Posted on 2024-03-14
2722 YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks
Tsao, N.; Olabode, J.; Rodell, R.; Sun, H.; Brickner, J. R.; Tsai, M.-S.; Pollina, E. A.; Chen, C.-K.; Mosammaparast, N.
10.1101/2024.03.14.585107 — molecular biology — Posted on 2024-03-14
2725 Highly conserved brain vascular receptor ALPL mediates transport of engineered viral vectors across the blood-brain barrier
Moyer, T. C.; Hoffman, B. A.; Chen, W.; Shah, I.; Ren, X.-Q.; Knox, T.; Liu, J.; Wang, W.; Li, J.; Khalid, H.; Kulkarni, A. S.; Egbuchulam, M.; Clement, J.; Bloedel, A.; Child, M. A.; Kaur, R.; Rouse, E.; Graham, K.; Maura, D.; Thorpe, Z.; Sayed-Zahid, A.; Chung, C. H.-Y.; Kutchin, A.; Johnson, A.; Yao, J.; Thompson, J.; Pande, N.; Nonnenmacher, M. E.
10.1101/2024.03.12.584703 — neuroscience — Posted on 2024-03-14
2726 Astrocyte CCN1 stabilizes neural circuits in the adult brain
Sancho, L.; Boisvert, M. M.; Dawoodtabar, T.; Burgado, J.; Wang, E.; Allen, N. J.
10.1101/2024.03.14.585077 — neuroscience — Posted on 2024-03-14
2728 Amyloid Beta Oligomers Accelerate ATP-Dependent Phase Separation of Ago2 to RNA Processing Bodies
Ray, S.; Roychowdhury, S.; Chakraborty, Y.; Banerjee, S.; Chattopadhyay, K.; Mukherjee, K.; Bhattacharyya, S. N.
10.1101/2024.03.14.584939 — neuroscience — Posted on 2024-03-14
2729 PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites
ALQAZZAZ, M.; Ciamponi, F. E.; Ho, J. C.; Maron, M. I.; Yadav, M.; Sababi, A. M.; Macleod, G.; Ahmadi, M.; Bullivant, G.; Tano, V.; Langley, S. R.; Osuna, M. S.; Sachamitr, P.; Kushida, M.; Richards, L. M.; Bardile, C. F.; Pouladi, M.; Pugh, T.; Tyers, M.; Angers, S.; Dirks, P. B.; Bader, G.; Massirer, K. B.; Barsyte-Lovejoy, D.; Shechter, D.; Harding, R. J.; Arrowsmith, C.; Prinos, P.
10.1101/2024.03.14.584861 — neuroscience — Posted on 2024-03-14
2730 Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression.
Pizzirusso, G.; Preka, E.; Goicolea, J.; Aguilar Ruiz, C.; Rodriguez Rodriguez, P.; Vazquez Cabrera, G.; Laterza, S.; Latorre Leal, L.; Eroli, F.; Blomgren, K.; Maioli, S.; Nilsson, P.; Fragkopoulou, A.; Fisahn, A.; Arroyo Garcia, L. E.
10.1101/2024.03.14.584993 — neuroscience — Posted on 2024-03-14
2733 Reactivation strength during cued recall is modulated by graph distance within cognitive maps
Kern, S.; Nagel, J.; Gerchen, M. F.; Gürsoy, C.; Meyer-Lindenberg, A.; Kirsch, P.; Dolan, R. J.; Gais, S.; Feld, G. B.
10.1101/2023.07.31.551234 — neuroscience — Posted on 2024-03-14
2734 Unraveling LIS1-Lissencephaly: Insights from Cerebral Organoids Suggest Severity-Dependent Genotype-Phenotype Correlations, Molecular Mechanisms and Therapeutic Strategies
Zillich, L.; Rossetti, A. C.; Fechtner, O.; Gasparotto, M.; Maillard, C.; Hoffrichter, A.; Zillich, E.; Jabali, A.; Marsoner, F.; Wilkens, R.; Schroeter, C. B.; Hentschel, A.; Meuth, S. G.; Ruck, T.; Koch, P.; Roos, A.; Bahi-Buisson, N.; Francis, F.; Ladewig, J.
10.1101/2022.12.19.520907 — neuroscience — Posted on 2024-03-14
2736 Pavlovian cue-evoked alcohol seeking is disrupted by ventral pallidal inhibition
Richard, J. M.; Armstrong, A.; Newell, B.; Muruganandan, P.; Janak, P. H.; Saunders, B. T.
10.1101/2024.03.14.585064 — neuroscience — Posted on 2024-03-14
2737 Distractor-response binding influences visual search
Allenmark, F.; Yu, H.; Müller, H. J.; Shi, Z.; Frings, C.
10.1101/2024.03.13.584838 — neuroscience — Posted on 2024-03-14
2738 Physical activity increases neuronal activity in the circadian clock of diurnal Arvicanthis ansorgei
Caputo, R.; Schoonderwoerd, R. A.; Ramkisoensing, A.; Janse, J. A. M.; van Diepen, H. C.; Raison, S.; Pevet, P.; Derks, N. A. V.; Sage-Ciocca, D.; Deboer, T.; Challet, E.; Meijer, J.
10.1101/2022.05.31.493966 — neuroscience — Posted on 2024-03-14
2739 Dental radiography as a low-invasive field technique to estimate age in small rodents, with the mole voles (Ellobius) as an example
Nikonova, V. R.; Naumova, A. E.; Bergaliev, A. M.; Dymskaya, M. M.; Rudyk, A. I.; Volodina, E. V.; Smorkatcheva, A.
10.1101/2024.03.14.585095 — zoology — Posted on 2024-03-14
2740 Natural soil suppressiveness against soilborne phytopathogens extends to the control of insect pest
Harmsen, N.; Vesga, P.; Glauser, G.; Klötzli, F.; Heiman, C. M.; Altenried, A.; Vacheron, J.; Muller, D.; Moënne-Loccoz, Y.; Steinger, T.; Keel, C.; Garrido-Sanz, D.
10.1101/2024.03.12.584584 — plant biology — Posted on 2024-03-14
2743 Exploiting WEE1 kinase activity as FUS::DDIT3-dependent therapeutic vulnerability in myxoid liposarcoma
Heinst, L.; Lee, K. S.; Berthold, R.; Isfort, I.; Wosnig, S.; Kuntze, A.; Hafner, S.; Altvater, B.; Roessig, C.; Aman, P.; Wardelmann, E.; Scholl, C.; Hartmann, W.; Froehling, S.; Trautmann, M.
10.1101/2024.03.13.584771 — cancer biology — Posted on 2024-03-14
2744 Biophysical metabolic modeling of complex bacterial colony morphology
Dukovski, I.; Golden, L.; Zhang, J.; Osborne, M.; Segre, D.; Korolev, K.
10.1101/2024.03.13.584915 — biophysics — Posted on 2024-03-14
2745 Application of Quantum Tensor Networks for Protein Classification
Kundu, D.; Ghosh, A.; Ekambaram, S.; Wang, J.; Dokholyan, N.; Ghosh, S.
10.1101/2024.03.11.584501 — bioinformatics — Posted on 2024-03-14
2749 Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product
Mishra, A.; Huang, S.-B.; Dubash, T.; Burr, R.; Wittner, B. S.; Cunneely, Q. E.; Putaturo, V. R.; Deshpande, A.; Antmen, E.; Gopinathan, K. A.; Otani, K.; Miyazawa, Y.; Kwak, J. E.; Guay, S. Y.; Kelly, J.; Walsh, J.; Nieman, L.; Galler, I.; Chan, P.; Lawrence, M. S.; Sullivan, R. J.; Bardia, A.; Micalizzi, D. S.; Sequist, L. V.; Lee, R. J.; Franses, J. W.; Ting, D. T.; Brunker, P. A. R.; Maheswaran, S.; Miyamoto, D. T.; Haber, D. A.; Toner, M.
10.1101/2024.03.13.583573 — bioengineering — Posted on 2024-03-14
2756 Spotlight on 10x Visium: a multi-sample protocol comparison of spatial technologies
Du, M. R. M.; Wang, C.; Law, C. W.; Amann-Zalcenstein, D.; Anttila, C. J. A.; Ling, L.; Hickey, P. F.; Sargeant, C. J.; Chen, Y.; Ioannidis, L. J.; Rajasekhar, P.; Yip, R. K. H.; Rogers, K. L.; Hansen, D. S.; Bowden, R.; Ritchie, M. E.
10.1101/2024.03.13.584910 — genomics — Posted on 2024-03-14
2760 A CLASP1 variant suggests a phenotypic relation with lissencephaly in humans
ALSAFH, R.; ALHASHEM, A.; ELSAYED, A.; YUEKSEL, Z.; GRAIES-TLILI, K.; THABET, F.; TABARKI, B.
10.1101/2024.03.12.584685 — genetics — Posted on 2024-03-14
2761 Experimental evolution of an RNA virus in Caenorhabditis elegans
Castiglioni, V. G.; Olmo-Uceda, M. J.; Martin, S.; Felix, M. A.; Gonzalez, R.; Elena, S. F.
10.1101/2024.03.14.584948 — evolutionary biology — Posted on 2024-03-14
2762 Circatidal control of gene expression in the deep-sea hot vent shrimp Rimicaris leurokolos
Zhang, H.; Yahagi, T.; Miyamoto, N.; Chen, C.; Jiang, Q.; Qian, P.-Y.; Sun, J.
10.1101/2024.01.12.575359 — ecology — Posted on 2024-03-14
2764 Soil viruses reduce greenhouse gas emissions and promote microbial necromass accrual
Liang, X.; Sun, S.; Zhong, Y.; Zhang, Y.; Wang, S.; Wang, Y.; Xie, N.; Yang, L.; Radosevich, M.
10.1101/2024.03.13.584929 — ecology — Posted on 2024-03-14
2767 DLG1 functions upstream of SDCCAG3 and IFT20 to control ciliary targeting of polycystin-2
Rezi, C. K.; Aslanyan, M.; Diwan, G. D.; Cheng, T.; Chamlali, M.; Junger, K.; Anvarian, Z.; lorentzen, e.; Pauly, K. B.; Bahadori, Y.; Fernandes, E. F.; Qian, F.; Tosi, S.; Christensen, S. T.; Pedersen, S. F.; Stromgaard, K.; Russell, R. B.; Miner, J. H.; Mahjoub, M. R.; Boldt, K.; Roepman, R.; Pedersen, L. B.
10.1101/2023.11.10.566524 — cell biology — Posted on 2024-03-14
2768 Regulation of Versican Expression in Macrophages is Mediated byCanonical Type I Interferon Signaling via ISGF3
Chang, M. Y.; Chan, C. K.; Brune, J. E.; Manicone, A.; Bomsztyk, K.; Frevert, C. W.; Altemeier, W. A.
10.1101/2024.03.14.585097 — cell biology — Posted on 2024-03-14
2769 Effective Gene Therapy for Metachromatic Leukodystrophy Achieved with Minimal Lentiviral Genomic Integrations
Tricoli, L.; Sase, S.; Hacker, J.; Pham, V.; Smith, S.; Chappell, M.; Breda, L.; Hurwitz, S.; Tanaka, N.; Castracani, C. C.; Guerra, A.; Hou, Z.; Schlotawa, L.; Radhakrishnan, K.; Kurre, P.; Ahrens-Nicklas, R.; Adang, L.; Vanderver, A.; Rivella, S.
10.1101/2024.03.14.584404 — molecular biology — Posted on 2024-03-14
2770 AQP1 Differentially Orchestrates Endothelial Cell Senescence
Shabanian, K.; Shabanian, T.; Karsai, G.; Lettlova, S.; Pontiggia, L.; Ruschitzka, F.; Beer, J. H.; Saeedi Saravi, S. S.
10.1101/2024.03.13.584782 — molecular biology — Posted on 2024-03-14
2771 Hsa_circ_0001304 promotes vascular smooth muscle cell autophagy and neointimal hyperplasia through the YTHDF2/mTOR axis
Mu, S.-Q.; Lin, J.-J.; Wang, Y.; Yang, L.-Y.; Wang, S.; Wang, Z.-Y.; Zhao, A.-Q.; Luo, W.-J.; Dong, Z.-Q.; Cao, Y.-G.; Jiang, Z.-A.; Wang, S.-F.; Cao, S.-H.; Meng, L.; Li, Y.; Yang, S.; Sun, S.-G.
10.1101/2024.03.13.584799 — molecular biology — Posted on 2024-03-14
2772 Experimental evolution of a reduced bacterial chemotaxis network
Kargeti, M.; Kalita, I.; Hoch, S.; Ratnikava, M.; Xu, W.; Ni, B.; Dy, R. L.; Colin, R.; Sourjik, V.
10.1101/2024.03.14.584839 — microbiology — Posted on 2024-03-14
2773 Assessing horizontal gene transfer in the rhizosphere of Brachypodium distachyon using fabricated ecosystems (EcoFABs)
Priya, S.; Rossbach, S.; Eng, T.; Andeer, P.; Lin, H.-H.; Mortimer, J.; Northen, T.; Mukhopadhyay, A.
10.1101/2024.03.14.584828 — microbiology — Posted on 2024-03-14
2774 Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity
Appios, A.; Davies, J.; Sirvent, S.; Henderson, S.; Trzebanski, S.; Schroth, J.; Law, M. L.; Boal Carvalho, I.; Yuan-Hao Kan, H.; Lovlekar, S.; Major, C.; Vallejo, A.; Hall, N. J.; Ardern-Jones, M.; Henson, S. M.; Emmerson, E.; Jung, S.; Polak, M. E.; Bennett, C. L.
10.1101/2023.11.13.566862 — immunology — Posted on 2024-03-14
2775 N-acetylcysteine counteracts immune dysfunction and autistic-related behaviors in the Shank3b mouse model of Autism Spectrum Disorders
Pangrazzi, L.; Cerilli, E.; Balasco, L.; Dall'O', G. M.; Chelini, G.; Pastore, A.; Weinberger, B.; Bozzi, Y.
10.1101/2024.03.13.584809 — immunology — Posted on 2024-03-14
2776 The extracellular heparan sulfatase SULF2 limits myeloid IFNbeta signaling and Th17 responses in inflammatory arthritis.
Swart, M.; Redpath, A.; Ogbechi, J.; Cardenas, R.; Topping, L.; Compeer, E. B.; Goddard, M.; Chanalaris, A.; Williams, R.; Brewer, D. S.; Smart, N.; Monaco, C.; Troeberg, L.
10.1101/2024.03.13.584823 — immunology — Posted on 2024-03-14
2777 Adoptive Transfer of CD49a+ Tissue Resident memory cells reverses pulmonary fibrosis in mice.
Collins, S. L.; Chan-Li, Y.; Shenderov, K.; Nelson, A. M.; Loube, J. M.; Mitzner, W. A.; Powell, J. D.; Horton, M. R.; Gillich, A.
10.1101/2024.03.13.584814 — immunology — Posted on 2024-03-14
2779 Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease
Chen, O. Y.; Vu, D. T.; Diaz, C. S.; Bodelet, J. S.; Phan, H.; Allali, G.; Nguyen, V.-D.; Cao, H.; He, X.; Muller, Y.; Zhi, B.; Shou, H.; Zhang, H.; He, W.; Wang, X.; Munafo, M.; Trung, N. L.; Nagels, G.; Ryvlin, P.; Pantaleo, G.
10.1101/2024.03.11.584383 — neuroscience — Posted on 2024-03-14
2780 A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson`s disease cell model
Hoellerhage, M.; Duan, L.; Chua, O. W. H.; Moebius, C.; Bothe, S.; Hopfner, F.; Wahl-Schott, C.; Bickle, M.; Hoeglinger, G. U.
10.1101/2024.03.13.584847 — neuroscience — Posted on 2024-03-14
2781 Increased perceptual reliability reduces membrane potential variability in cortical neurons
von Hünerbein, B.; Jordan, J.; Oude Lohuis, M.; Marchesi, P.; Olcese, U.; Pennartz, C. M. A.; Senn, W.; Petrovici, M. A.
10.1101/2024.03.13.584630 — neuroscience — Posted on 2024-03-14
2783 Forelimb movements contribute to hindlimb cutaneous reflexes during locomotion in cats
Harnie, J.; Al Arab, R.; Mari, S.; Yassine, S.; Eddaoui, O.; Jehannin, P.; Audet, J.; Lecomte, C. G.; Iorio-Morin, C.; Prilutsky, B. I.; Rybak, I. A.; Frigon, A.
10.1101/2024.03.13.584812 — neuroscience — Posted on 2024-03-14
2786 Neurexin drives C. elegans avoidance behavior independently of its post-synaptic binding partner Neuroligin
Muirhead, C. S.; Reddy, K. C.; Guerra, S.; Rieger, M.; Hart, M. P.; Srinivasan, J.; Chalasani, S. H.
10.1101/2024.03.12.584644 — neuroscience — Posted on 2024-03-14
2787 Functional analysis of the epilepsy gene Pcdh19 using a novel GFP-reporter mouse model
Mincheva-Tasheva, S.; Scherer, M.; Robertson, L. J.; Piltz, S.; Bensalem, J.; Pederick, D. T.; Thomas, P. Q.
10.1101/2024.03.14.584898 — neuroscience — Posted on 2024-03-14
2788 The effect of gravity on hand spatio-temporal kinematic features during functional movements
Bucchieri, A.; Tessari, F.; Buccelli, S.; De Momi, E.; Laffranchi, M.; De Michieli, L.
10.1101/2023.12.05.570204 — neuroscience — Posted on 2024-03-14
2789 Reduced GABA transmission onto ventral tegmental area dopamine neurons underlies vulnerability for hyperactivity in a mouse model of Anorexia Nervosa
Ducrocq, F.; Brouwer, E.; Kooij, K. L.; Wolterink-Donselaar, I. G.; Drost, L.; Hak, J.; Veendijk, M.; Luijendijk, M. C. M.; Meye, F. J.; Adan, R. A. H.
10.1101/2024.03.14.585038 — neuroscience — Posted on 2024-03-14
2790 Enhancer-targeted CRISPR-Activation Rescues Haploinsufficient Autism Susceptibility Genes
Chen, G. T.; Nair, G.; Osorio, A. J.; Holley, S. M.; Ghassemzadeh, K.; Gonzalez, J. G.; Lu, C.; Sanjana, N. E.; Cepeda, C.; Geschwind, D.
10.1101/2024.03.13.584921 — neuroscience — Posted on 2024-03-14
2791 Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants
Shipman, A.; Gao, Y.; Liu, D.; Sun, S.; Zang, J.; Syed, Z.; Bhagavathi, A.; Smith, E.; Erickson, T.; Hill, M.; Neuhauss, S. C.; Sui, S.-F.; Nicolson, T.
10.1101/2024.03.13.584854 — neuroscience — Posted on 2024-03-14
2792 When visual attention is divided in the flash-lag effect
Yook, J.; Hogendoorn, H.; Fink, G. R.; Vossel, S.; Weidner, R.
10.1101/2024.03.14.585092 — neuroscience — Posted on 2024-03-14
2795 Characterizing an electronic-robotic targeting platform for precise and fast brain stimulation with multi-locus transcranial magnetic stimulation
Matsuda, R. H.; Souza, V. H.; Marchetti, T.; De La Cruz, A. S.; Kahilakoski, O.-P.; Laine, M.; Sinisalo, H.; Kicic, D.; Lioumis, P.; Ilmoniemi, R.; Baffa, O.
10.1101/2024.03.12.584601 — neuroscience — Posted on 2024-03-14
2797 Early-life stress alters chromatin modifications in VTA to prime stress sensitivity
Geiger, L. T.; Balouek, J.-A. R.; Farrelly, L. A.; Chen, A. S.; Tang, M.; Bennett, S. N.; Nestler, E. J.; Garcia, B. A.; Maze, I.; Pena, C. J.
10.1101/2024.03.14.584631 — neuroscience — Posted on 2024-03-14
2798 Assessing Individual Sensitivity to the Thermal Grill Illusion: A Two-Dimensional Adaptive Psychophysical Approach
Sardeto Deolindo, C.; Ehmsen, J. F.; Courtin, A. S.; Mitchell, A. G.; Kraenge, C. E.; Nikolova, N.; Allen, M. G.; Fardo, F.
10.1101/2024.03.14.585017 — neuroscience — Posted on 2024-03-14
2799 Decoding the Cognitive map: Learning place cells and remapping
Pettersen, M. B.; Schoyen, V. S.; Malthe-Sorenssen, A.; Lepperod, M. E.
10.1101/2024.03.14.585049 — neuroscience — Posted on 2024-03-14
2801 Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms
Lambourne, L.; Mattioli, K.; Santoso, C.; Sheynkman, G.; Inukai, S.; Kaundal, B.; Berenson, A.; Spirohn-Fitzgerald, K.; Bhattacharjee, A.; Rothman, E.; Shrestha, S.; Laval, F.; Yang, Z.; Bisht, D.; Sewell, J. A.; Li, G.; Prasad, A.; Phanor, S.; Lane, R.; Campbell, D. M.; Hunt, T.; Balcha, D.; Gebbia, M.; Twizere, J.-C.; Hao, T.; Frankish, A.; Riback, J.; Salomonis, N.; Calderwood, M. A.; Hill, D. E.; Sahni, N.; Vidal, M.; Bulyk, M. L.; Fuxman Bass, J. I.
10.1101/2024.03.12.584681 — systems biology — Posted on 2024-03-14
2804 Automated Seminal Root Angle Measurement with Corrective Annotation
Smith, A. G.; Malinowska, M.; Ruud, A. K.; Janss, L.; Krusell, L.; Jensen, J. D.; Asp, T.
10.1101/2024.03.13.584803 — plant biology — Posted on 2024-03-14
2805 The molecular basis of pine wilt disease resistance in Pinus massoniana
wang, j.; Cai, S.; Zeng, L.; Tong, J.; Hang, D.; Zhang, X.; Fang, Y.; SU, J.; Su, S.
10.1101/2024.03.13.584545 — plant biology — Posted on 2024-03-14
2806 Muscle fiber Myc is dispensable for muscle growth and forced expression severely perturbs homeostasis
Ham, D. J.; Semeraro, M.; Berger, B. M.; Lin, S.; Maino, E.; Oliveri, F.; Ruegg, M. A.
10.1101/2024.03.13.584777 — physiology — Posted on 2024-03-14
2809 Forecasting Dengue Fever in Brazil Using Multimodal Data, Including Climate Data
Danko, D. C.; Vorosmarty, C.; Cak, A.; Corsi, F.; Patel, S.; Papciak, J.; Wells, H.; Albanese, A.; Mason, C. E.; Maciel-de-Freitas, R.; Nagy-Szakal, D.; OHara, N. B.
10.1101/2024.03.12.584724 — bioinformatics — Posted on 2024-03-14
2810 An unsupervised deep learning framework encodes super-resolved image features to decode bacterial cell cycle
Griffie, J.; Zhang, C.; Denereaz, J.; Pham, T.-A. M.; Weissbart, G.; Sieben, C.; Lambert, A.; Veening, J.-W.; Manley, S.
10.1101/2024.03.13.584804 — bioinformatics — Posted on 2024-03-14
2815 Deciphering Immune Complexity: Single-Cell Insights into Autoimmune Myocarditis Progression
Mamdouh, F.; Abdulsahib, W. K.; Alshaya, D. S.; Fayad, E.; Eid, R. A.; Alsharif, G.; Alshehri, M. A.; Otifi, H. M.; Soltan, M. A.; Eldeen, M. A.
10.1101/2024.03.12.584698 — genomics — Posted on 2024-03-14
2818 Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice
Noh, M.; Che, X.; Jin, X.; Lee, D.-K.; Kim, H.-J.; Park, D. R.; Lee, S. Y.; Lee, H.; Gardella, T. J.; Choi, J.-Y.; Lee, S.
10.1101/2024.03.13.584815 — genomics — Posted on 2024-03-14
2820 Discovery of knock-down resistance in the major malaria vector Anopheles funestus reveals the legacy of persistent DDT pollution.
Odero, J.; Dennis, T. P.; Polo, B.; Nwezeobi, J.; Bodde, M.; Nagi, S. C.; Hernandez-Koutoucheva, A.; Nambunga, I. H.; Bwanary, H.; Mkandawile, G.; Govella, N. J.; Kaindoa, E. W.; Ferguson, H. M.; Ochomo, E.; Clarkson, C. S.; Miles, A. M.; Lawniczak, M. K. N.; Weetman, D.; Baldini, F.; Okumu, F. O.
10.1101/2024.03.13.584754 — genetics — Posted on 2024-03-14
2821 Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
Lin, X.; Gupta, D.; Vaitsiankova, A.; Bhandari, S. K.; Leung, K. S. K.; Menolfi, D.; Lee, B. J.; Russell, H. R.; Gershik, S.; Gu, W.; McKinnon, P. J.; DANTZER, F.; Rothenberg, E.; Tomkinson, A. E.; Zha, S.
10.1101/2024.03.12.584665 — genetics — Posted on 2024-03-14
2826 Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy
Feng, Y.; Diego, K. S.; Dong, Z.; Wick, Z. C.; Page-Harley, L.; Page-Harley, V.; Schnipper, J.; Lamsifer, S. I.; Pennington, Z. T.; Vetere, L. M.; Philipsberg, P. A.; Soler, I.; Jurkowski, A.; Rosado, C. J.; Khan, N. N.; Cai, D. J.; Shuman, T.
10.1101/2024.03.12.584697 — neuroscience — Posted on 2024-03-14
2827 Reliability of brain metrics derived from a Time-Domain Functional Near-Infrared Spectroscopy System
Dubois, J.; Field, R. M.; Jawhar, S.; Koch, E. M.; Aghajan, Z. M.; Miller, N.; Perdue, K. L.; Taylor, M.
10.1101/2024.03.12.584660 — neuroscience — Posted on 2024-03-14
2832 Psilocybin prevents activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms.
Conn, K.; Milton, L. K.; Huang, K.; Munguba, H.; Ruuska, J.; Lemus, M. B.; Greaves, E.; Homman-Ludiye, J.; Oldfield, B. J.; Foldi, C. J.
10.1101/2023.12.12.571374 — neuroscience — Posted on 2024-03-14
2834 The Pivotal Involvement of the Respiratory burst oxidase G (SlRbohG) Gene in H2O2 Production Under Stress for Proper Na+ Homeostasis Regulation in Tomato
Egea, I.; Barragan-Lozano, T.; Estrada, Y.; Jaquez-Gutierrez, M.; Plasencia, F. A.; Atares, A.; Garcia-Sogo, B.; Capel, C.; Yuste-Lisbona, F. J.; Egea-Sanchez, J. M.; Borja-Flores, F.; Angosto, T.; Moreno, V.; Lozano, R.; Pineda, B.
10.1101/2024.03.12.584686 — plant biology — Posted on 2024-03-14
2837 Heterochromatin spreading in cancer cells through HDAC7 mediated histone H3.3 landscape reprogramming.
Hassan, O.; Pizzagalli, M.; Wu, L. J.; Karambizi, D.; Zepecki, J. P.; Fajardo, E.; Fiser, A.; Tapinos, N.
10.1101/2024.03.12.584656 — cancer biology — Posted on 2024-03-14
2839 Conditional c-MYC activation in catecholaminergic cells drives distinct neuroendocrine tumors: neuroblastoma vs somatostatinoma
YANG, J.; Wang, T.; Liu, L.; Fang, J.; Jin, H.; Natarajan, S.; Sheppard, H.; Lu, M.; Turner, G.; Confer, T.; Johnson, M.; Steinberg, J.; Ha, L.; Yadak, N.; Jain, R.; Picketts, D.; Ma, X.; Murphy, A.; Davidoff, A.; Glazer, E.; Easton, J.; Chen, X.; Wang, R.
10.1101/2024.03.12.584622 — cancer biology — Posted on 2024-03-14
2840 Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy
Saecker, R. M.; Mueller, A. U.; Malone, B.; Chen, J.; Budell, W. C.; Dandey, V. P.; Maruthi, K.; Mendez, J. H.; Molina, N.; Eng, E. T.; Yen, L. Y.; Potter, C. S.; Carragher, B.; Darst, S. A.
10.1101/2024.03.13.584744 — biophysics — Posted on 2024-03-14
2842 Seq2MAIT: A Novel Deep Learning Framework for Identifying Mucosal Associated Invariant T (MAIT) Cells
ElAbd, H.; Byron, R.; Woodhouse, S.; Robinett, B.; Sulc, J.; Franke, A.; Pesesky, M.; Zhou, W.; Chen-Harris, H.; Howie, B.; Taniguchi, R.; Robins, H.
10.1101/2024.03.12.584395 — bioinformatics — Posted on 2024-03-14
2849 Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis
Bandyadka, S.; Lebo, D. P.; Mondragon, A.; Serizier, S. B.; Kwan, J.; Peterson, J. S.; Chasse, A. Y.; Jenkins, V.; Calikyan, A.; Ortega, A.; Campbell, J. D.; Emili, A.; McCall, K.
10.1101/2024.03.12.584558 — genetics — Posted on 2024-03-14
2852 The best of two worlds: using stacked generalization for integrating expert range maps in species distribution models
Oeser, J.; Zurell, D.; Mayer, F.; Coraman, E.; Toshkova, N.; Deleva, S.; Natradze, I.; Benda, P.; Ghazaryan, A.; Irmak, S.; Hasanov, N. A.; Guliyeva, G. G.; Gritsina, M.
10.1101/2024.03.12.584552 — ecology — Posted on 2024-03-14
2853 Circular RNA circASH1L(4,5) protects microRNA-129-5p from target-directed microRNA degradation in human skin wound healing
Wang, Q.; Niu, G.; Liu, Z.; Toma, M. A.; Geara, J.; Bian, X.; Zhang, L.; Piipponen, M.; Li, D.; Sommar, P.; Xu Landen, N.
10.1101/2024.03.12.584463 — molecular biology — Posted on 2024-03-14
2855 Type I interferon alters invasive extravillous trophoblast function.
Simoni, M. K.; Negatu, S. G.; Park, J. Y.; Mani, S.; Arreguin, M.; Amses, K.; Huh, D. D.; Mainigi, M.; Jurado, K. A.
10.1101/2024.03.11.584521 — immunology — Posted on 2024-03-14
2856 Morphometric Analysis of the Thymic Epithelial Cell (TEC) Network Using Integrated and Orthogonal Digital Pathology Approaches
Lagou, M. K.; Argyris, D. G.; Vodopyanov, S.; Gunther-Cummins, L.; Hardas, A.; Poutahidis, T.; Panorias, C.; DesMarais, S.; Entenberg, C.; Carpenter, R. S.; Guzik, H.; Nishku, X.; Churaman, J.; Maryanovich, M.; DesMarais, V.; Macaluso, F. P.; Karagiannis, G. S.
10.1101/2024.03.11.584509 — immunology — Posted on 2024-03-14
2857 Investigating the Role and Regulation of GPNMB in Progranulin-deficient Macrophages
Gillett, D. A.; Neighbarger, N. K.; Cole, C.; Wallings, R.; Tansey, M. G.
10.1101/2024.03.12.584649 — immunology — Posted on 2024-03-14
2858 Pretrauma cognitive traits predict trauma-induced fear generalization and associated prefrontal functioning in a longitudinal model of posttraumatic stress disorder
Szente, L.; Aliczki, M.; Balla, G. Y.; Marothy, R. D.; Varga, Z. K.; Varga, B. A.; Borhegyi, Z.; Biro, L.; Demeter, K.; Miskolczi, C.; Balogh, Z.; Szebik, H.; Szilvasy-Szabo, A.; Kurilla, A.; Toth, M.; Mikics, E.
10.1101/2024.03.11.584500 — neuroscience — Posted on 2024-03-14
2860 Subject-Agnostic Transformer-Based Neural Speech Decoding from Surface and Depth Electrode Signals
Chen, J.; CHEN, X.; Wang, R.; Le, C.; Khalilian-Gourtani, A.; Jensen, E.; Dugan, P.; Doyle, W.; Devinsky, O.; Friedman, D.; Flinker, A.; Wang, Y.
10.1101/2024.03.11.584533 — neuroscience — Posted on 2024-03-14
2861 Alteration of nociceptive Schwann cells in a mouse model of peripheral neuropathy in prediabetic condition
Rastoldo, G.; Jaafar, A. K.; Paulo-Ramos, A.; Thouvenot, K.; Planesse, C.; Bringart, M.; Gonthier, M.-P.; Lambert, G.; Bourane, S.
10.1101/2024.03.12.584541 — neuroscience — Posted on 2024-03-14
2863 Small animal brain surgery with neither a brain atlas nor a stereotaxic frame
Ron, S.; Beeri, H.; Shinover, O.; Tur, N. M.; Brokman, J.; Engelhard, B.; Gutfreund, Y.
10.1101/2024.03.12.584491 — neuroscience — Posted on 2024-03-14
2865 A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimers Disease
Jin, M.; Ma, Z.; Dang, R.; Zhang, H.; Xue, H.; Pascual, J.; Finkbeiner, S.; Head, E.; Liu, Y.; Jiang, P.
10.1101/2024.03.12.584646 — neuroscience — Posted on 2024-03-14
2866 Contrast-enhanced ultrasound imaging detects anatomical and functional changes in rat cervical spine microvasculature with normal aging
Harmon, J. N.; Chandran, P.; Chandrasekaran, A.; Hyde, J. E.; Hernandez, G. J.; Reed, M. J.; Bruce, M. F.; Khaing, Z. Z.
10.1101/2024.03.12.584672 — neuroscience — Posted on 2024-03-14
2867 Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens
Martinez-Rivera, F. J.; Holt, L. M.; Minier-Toribio, A.; Estill, M.; Yeh, S.-Y.; Tofani, S.; Futamura, R.; Browne, C. J.; Mews, P.; Shen, L.; Nestler, E. J.
10.1101/2024.03.12.584637 — neuroscience — Posted on 2024-03-14
2870 Enabling Greenhouse Gas Emission Reduction while Improving Rice Yield with a Methane-Derived Microbial Biostimulant
Rajeev Kumar, S.; David, E. M.; Pavithra, G. J.; Sajith, G. K.; Lesharadevi, K.; Akshaya, S.; Bassavaraddi, C.; Navyashree, G.; Arpitha, P. S.; Sreedevi, P.; Zainuddin, K.; Saiyyeda, F.; Babu, B. R.; Prashanth, M. U.; Ravikumar, G.; Basavaraj, P.; Kumar, C. S.; Kumar, V. M. L. D.; Parthasarathi, T.; Subbian, E.
10.1101/2024.03.13.584920 — plant biology — Posted on 2024-03-14
2871 A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells
Babin-Ebell, A.; Mao, Y.; Baljkas, T.; Pilz, F.; Winkler, M.; Kuerschner, S.; Hoffarth, M.; Goerdt, S.; Reiners-Koch, P.-S.; Singhal, M.
10.1101/2024.03.11.584492 — physiology — Posted on 2024-03-14
2872 Deciphering molecular mechanisms of synergistic growth reduction in kinase inhibitor combinations
Tsirvouli, E.; Martinez del Val, A.; Thommesen, L.; Laegreid, A.; Kuiper, M.; Olsen, J. V.; Flobak, A.
10.1101/2024.03.12.584561 — cancer biology — Posted on 2024-03-14
2873 Bridging Domains in Chronic Lower Back Pain: Large Language Models and Ontology-driven Strategies for Knowledge Graph Construction
Anderson, P. E.; Davidson, J. M.; Lin, D.; Migler, T.; Ho, I.; Koenig, C.; Bittner, M.; Kaplan, S.; Paraiso, M.; Buhn, N.; Stokes, E.; Hunt, T.; Ropella, G.; Lotz, J.
10.1101/2024.03.11.584505 — bioinformatics — Posted on 2024-03-14
2875 AUTO-TUNE: SELECTING THE DISTANCE THRESHOLD FOR INFERRING HIV TRANSMISSION CLUSTERS
Weaver, S.; Davila-Conn, V. M.; Ji, D.; Avila-Rios, S.; Leigh Brown, A.; Wertheim, J.; Kosakovsky Pond, S. L.
10.1101/2024.03.11.584522 — bioinformatics — Posted on 2024-03-14
2877 In-Space Fabrication of Janus Base Nano-Matrix for Improved Assembly and Bioactivities
Yau, A.; Landolina, M.; Snow, M. A.; Mesci, P.; Williams, B.; Hoying, J. B.; Duflo, D.; Wu, H.; Stoudemire, J.; Hernandez, R.; Chen, Y.
10.1101/2024.03.11.584527 — bioengineering — Posted on 2024-03-14
2879 Whole-body simulation of realistic fruit fly locomotion with deep reinforcement learning
Vaxenburg, R.; Siwanowicz, I.; Merel, J.; Robie, A. A.; Morrow, C.; Novati, G.; Stefanidi, Z.; Card, G. M.; Reiser, M. B.; Botvinick, M. M.; Branson, K. M.; Tassa, Y.; Turaga, S. C.
10.1101/2024.03.11.584515 — animal behavior and cognition — Posted on 2024-03-14
2884 Convergent gene expression in epithelial cells illuminates the evolution of uterine receptivity
Brulport, A.; Gazda, M. A.; Daunesse, M.; Liorzou, E.; Raquillet, B.; Lepelletier, A.; Sopena-Rios, M.; Regnard, P.; Fellmann, L.; Faccin, L.; Garbit, S.; Cermolacce, A.; Kondova, I.; Raliou, M.; Marcellin, L.; Abo, C.; Doridot, L.; Berthelot, C.
10.1101/2024.03.13.584751 — evolutionary biology — Posted on 2024-03-14
2887 Direct inhibitors of InhA with efficacy similar or superior to isoniazid in novel drug regimens for tuberculosis
Encinas, L.; Li, S.-Y.; Rullas-Trincado, J.; Tasneen, R.; TYAGI, S.; Soni, H.; garcia-perez, a.; Lee, J.; Gonzalez del Rio, R.; De Mercado, J.; Sousa, V.; Sosi?, I.; Gobec, S.; Mendoza-Losana, A.; Converse, P. J.; Mdluli, K.; Fotouhi, N.; BARROS-AGUIRRE, D.; Nuermberger, E. L.
10.1101/2024.03.08.584126 — pharmacology and toxicology — Posted on 2024-03-14
2888 Steppe Ancestry in western Eurasia and the spread of the Germanic Languages
McColl, H.; Kroonen, G.; Moreno-Mayar, J. V.; Valeur Seersholm, F.; Scorrano, G.; Pinotti, T.; Vimala, T.; Sindbaek, S. M.; Ethelberg, P.; Fyfe, R.; Gaillard, M.-J.; Larsen, H. M. E.; Mortensen, M. F.; Demeter, F.; Jorkov, M. L. S.; Bergerbrant, S.; Damgaard, P. d. B.; Allentoft, M. E.; Vinner, L.; Gaunitz, C.; Ramsoe, A.; Altinkaya, I.; Amund Henriksen, R.; Irving-Pease, E. K.; Sabatini, S.; Fischer, A.; Barrie, W.; Ingason, A.; Rosengren, A.; Vaughn, A.; Cao, J.; Staring, J.; Stenderup, J.; Yediay, F. E.; Ahlstrom, T.; Albris, S. L.; Atabiev, B.; Bangsgaard, P.; Belcastro, M. G.; Card, N.; C
10.1101/2024.03.13.584607 — genetics — Posted on 2024-03-14
2889 The evolutionary history of the ancient weevil family Belidae (Coleoptera: Curculionoidea) reveals the marks of Gondwana breakup and major floristic turnovers, including the rise of angiosperms
Li, X.; Marvaldi, A. E.; Oberprieler, R. G.; Clarke, D.; Farrell, B. D.; Sequeira, A.; Ferrer, M. S.; O'Brien, C.; Salzman, S.; Shin, S.; Tang, W.; McKenna, D. D.
10.1101/2024.03.12.584611 — evolutionary biology — Posted on 2024-03-14
2892 Engineered Migrasomes: A Robust, Thermally Stable Vaccination Platform
Wang, D.; Wang, H.; Wan, W.; Zhu, Z.; Sho, T.; Zheng, Y.; Zhang, X.; Dou, L.; Ding, Q.; Yu, L.; Liu, Z.
10.1101/2024.03.13.584850 — cell biology — Posted on 2024-03-14
2895 Primate thalamic nuclei select abstract rules and shape prefrontal dynamics
Phillips, J. M.; Afrasiabi, M.; Kambi, N. A.; Redinbaugh, M. J.; Steely, S.; Johnson, E. R.; Cheng, X.; Fayyad, M.; Mohanta, S.; Caris, A.; Mikell, C. B.; Mofakham, S.; Saalmann, Y. B.
10.1101/2024.03.13.584871 — neuroscience — Posted on 2024-03-14
2896 Protection against APOE4-associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice
McGill, C. J.; Christensen, A.; Qian, W.; Thorwald, M. A.; Lugo, J. G.; Namvari, S.; White, O. S.; Finch, C.; Benayoun, B. A.; Pike, C. J.
10.1101/2024.03.12.584678 — systems biology — Posted on 2024-03-14
2897 Molecular signatures and associated regulators of the pea leaf response to sulfur deficiency and water deficit as revealed by multi-omics analyses
Bonnot, T.; Henriet, C.; Aime, D.; Kreplak, J.; Terezol, M.; Balliau, T.; Ourry, A.; Zivy, M.; Vernoud, V.; Gallardo, K.
10.1101/2024.03.13.582463 — plant biology — Posted on 2024-03-14
2898 Assessing Long-Term Stored Tissues for Multi-Omics Data Quality and Proteogenomics Suitability
Song, K. J.; Kim, M.; Heo, Y. J.; Cho, K.-C.; Oh, J.-W.; Kim, D. H.; Hwa, C.; Do, Y.; Choi, S.; Hwang, H. S.; Kim, K.; Kim, K.; Na, S.; Paek, E.; An, J.-Y.; Jang, S. J.; Kim, M.-S.; Kim, K. P.
10.1101/2024.03.13.583805 — cancer biology — Posted on 2024-03-14
2899 Proteomic Analysis Reveals Trilaciclib-Induced Senescence
Hermosilla-Trespaderne, M.; Hu-Yang, M. X.; Dannoura, A.; Frey, A. M.; George, A. L.; Trost, M.; Marin-Rubio, J. L.
10.1101/2024.03.12.584620 — cancer biology — Posted on 2024-03-14
2900 CDK4 and CDK6 upregulation promotes DNA replication stress, genomic instability and resistance to EGFR targeted therapy in lung cancer
Gini, B.; Gui, P.; Wu, W.; Kerr, D. L.; Tan, L.; Barbosa, D.; Olivas, V.; Gomez, C.; Elmes, S.; Steri, V.; Chakrabarti, T.; Bivona, T. G.; Blakely, C. M.
10.1101/2024.03.12.584638 — cancer biology — Posted on 2024-03-14
2901 Comparative Evaluation of Bioinformatic Pipelines for Full-Length Viral Genome Assembly
Zsichla, L.; Zeeb, M.; Fazekas, D.; Ay, E.; Muller, D.; Metzner, K.; Kouyos, R.; Muller, V.
10.1101/2024.03.13.584779 — bioinformatics — Posted on 2024-03-14
2907 Tribus: Semi-automated discovery of cell identities and phenotypes from multiplexed imaging and proteomicdata
Kang, Z.; Szabo, A.; Farago, T.; Perez-Villatoro, F.; Launonen, I.-M.; Anttila, E.; Elias, K.; Casado, J.; Sorger, P. K.; Farkkila, A.
10.1101/2024.03.13.584767 — bioinformatics — Posted on 2024-03-14
2909 The repetitive genome of the Ixodes ricinus tick reveals transposable elements have driven genome evolution in ticks
Ronai, I.; de Paula Baptista, R.; Paulat, N. S.; Frederick, J.; Azagi, T.; Bakker, J.; Dillon, K. C.; Sprong, H.; Ray, D. A.; Glenn, T.
10.1101/2024.03.13.584159 — genomics — Posted on 2024-03-14
2910 The dynamic genomes of Hydra and the anciently active repeat complement of animal chromosomes
Kon-Nanjo, K.; Kon, T.; Koubkova Yu, T. C.-T.; Rodriguez-Terrones, D.; Falcon, F.; Martinez, D. E.; Steele, R. E.; Tanaka, E. M.; Holstein, T. W.; Simakov, O.
10.1101/2024.03.13.584568 — genomics — Posted on 2024-03-14
2915 De novo evolution of transmissible tumors in Hydra
Tissot, S.; Meliani, J.; Boutry, J.; Brazier, L.; Tökkölyi, J.; Roche, B.; Ujvari, B.; Nedelcu, A. M.; Thomas, F.; Dujon, A. M.
10.1101/2024.03.13.584762 — evolutionary biology — Posted on 2024-03-14
2916 Temporal and spatial variability in availability bias has consequences for marine bird abundance estimates during the non-breeding season
Dunn, R. E.; Duckworth, J.; O'Brien, S.; Furness, R. W.; Buckingham, L.; Daunt, F.; Bogdanova, M. I.; Green, J. A.
10.1101/2024.03.13.584773 — ecology — Posted on 2024-03-14
2919 Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest
Casey-Clyde, T.; Liu, S. J.; Serrano, J. A. C.; Teng, C.; Jang, Y.-G.; Vasudevan, H. N.; Bush, J. O.; Raleigh, D. R.
10.1101/2024.03.13.584903 — developmental biology — Posted on 2024-03-14
2922 Intraspecific venom variation in the medically important puff adder (Bitis arietans): comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom
Dawson, C. A.; Bartlett, K. E.; Wilkinson, M. C.; Ainsworth, S.; Albulescu, L.-O.; Kazandjian, T.; Hall, S. R.; Westhorpe, A.; Clare, R. H.; Wagstaff, S.; Modahl, C. M.; Harrison, R. A.; Casewell, N. R.
10.1101/2024.03.13.584772 — molecular biology — Posted on 2024-03-14
2923 A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring
Dowrey, T. W.; Cranston, S. F.; Skvir, N.; Lok, Y.; Gould, B.; Petrowitz, B.; Villar, D.; Shan, J.; James, M.; Dodge, M.; Belkina, A. C.; Giadone, R. M.; Sebastiani, P.; Perls, T. T.; Andersen, S. L.; Murphy, G. J.
10.1101/2024.03.12.584663 — molecular biology — Posted on 2024-03-14
2925 Mutability and hypermutation antagonize immunoglobulin codon optimality
McGrath, J. J.; Park, J.; Troxell, C. A.; Chervin, J. C.; Li, L.; Kent, J. R.; Changrob, S.; Fu, Y.; Huang, M.; Zheng, N.-Y.; Wilbanks, G. D.; Nelson, S. A.; Sun, J.; Inghirami, G.; Madariaga, M. L. L.; Georgiou, G.; Wilson, P. C.
10.1101/2024.03.13.584690 — immunology — Posted on 2024-03-14
2928 Transcriptional and neurochemical signatures of cerebral blood flow alterations in schizophrenia and the clinical high-risk state for psychosis
Knight, S. R.; Abbasova, L.; Zeighami, Y.; Hansen, J. Y.; Martins, D.; Zelaya, F.; Dipasquale, O.; Liu, T.; Shin, D.; Bossong, M. G.; Azis, M.; Antoniades, M.; Howes, O. D.; Bonoldi, I.; Egerton, A.; Allen, P.; O'Daly, O.; McGuire, P.; Modinos, G.
10.1101/2024.03.13.583894 — neuroscience — Posted on 2024-03-14
2930 Bayesian inference of state feedback control parameters for fo perturbation responses in cerebellar ataxia
Gaines, J. L.; Kim, K. S.; Parrell, B.; Ramanarayanan, V.; Pongos, A. L.; Nagarajan, S. S.; Houde, J. F.
10.1101/2024.03.12.584554 — neuroscience — Posted on 2024-03-14
2934 The pivotal role of Drgx in survival, wiring and identity of T4/T5 neurons
Gizler, L.; Schneider, K.; Steigleder, S.; Benmaamar, S.; Schneuwly, S.; Rass, M.
10.1101/2024.03.12.584653 — developmental biology — Posted on 2024-03-14
2935 Spatial Dynamics of the Developing Human Heart
Lazar, E.; Mauron, R.; Andrusivova, Z.; Foyer, J.; Larsson, L.; Shakari, N.; Salas, S. M.; Sariyar, S.; Hansen, J. N.; Vicari, M.; Czarnewski, P.; Braun, E.; Li, X.; Bergmann, O.; Sylven, C.; Lundberg, E.; Linnarsson, S.; Nilsson, M.; Sundstrom, E.; Adameyko, I.; Lundeberg, J.
10.1101/2024.03.12.584577 — developmental biology — Posted on 2024-03-14
2938 Two brain systems for the perception of geometric shapes
Sable-Meyer, M.; Benjamin, L.; Watkins, C. P.; He, C.; Al Roumi, F.; Dehaene, S.
10.1101/2024.03.13.584141 — neuroscience — Posted on 2024-03-14
2939 QClus: A droplet-filtering algorithm for enhanced snRNA-seq data quality in challenging samples
Schmauch, E.; Ojanen, J.; Galani, K.; Jalkanen, J.; Harju, K.; Hollmen, M.; Kokki, H.; Gunn, J.; Halonen, J.; Hartikainen, J.; Kiviniemi, T.; Tavi, P.; Kaikkonen, M. U.; Kellis, M.; Linna-Kuosmanen, S.
10.1101/2022.10.21.513315 — genomics — Posted on 2024-03-13
2940 Decoding the complexity of delayed wound healing following Enterococcus faecalis infection
Celik, C.; Lee, S. Y. T.; Reinhart Tanoto, F.; Veleba, M.; Kline, K. A.; Thibault, G.
10.1101/2023.11.16.566967 — microbiology — Posted on 2024-03-13
2941 Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho-vanillin
Woods, K. E.; Akhter, S.; Rodriguez, B. L.; Townsend, K. A.; Smith, N. C.; Wambua, A. N.; Craddock, V.; Santa, E. E.; Manson, D. E.; Abisado-Duque, R. G.; Oakley, B. R.; Hancock, L. E.; Miao, Y.; Blackwell, H. E.; Chandler, J. R.
10.1101/2024.02.24.581676 — microbiology — Posted on 2024-03-13
2942 Assessment of Neurovascular Uncoupling: APOE Status is a Key Driver of Early Metabolic and Vascular Dysfunction
Onos, K. D.; Lin, P. B.; Pandy, R. S.; Persohn, S. A.; Burton, C. P.; Miner, E. W.; Eldridge, K.; Kanyinda, J. N.; Foley, K. E.; Carter, G. W.; Howell, G. R.; Territo, P. R.
10.1101/2023.12.13.571584 — neuroscience — Posted on 2024-03-13
2943 Monkeys have rhythm
Rajendran, V. G.; Marquez, J. P.; Prado, L.; Merchant, H.
10.1101/2024.03.11.584468 — neuroscience — Posted on 2024-03-13
2944 Development of a series of genetically engineered NTRK fusion-driven pediatric-type high-grade glioma mouse models
Schmid, S.; Russell, Z. R.; Yamashita, A. S.; West, M. E.; Parrish, A. G.; Walker, J.; Rudoy, D.; Yan, J. Z.; Quist, D. C.; Gessesse, B. N.; Alvinez, N.; Cimino, P. J.; Kumasaka, D. K.; Parchment, R. E.; Holland, E. C.; Szulzewsky, F.
10.1101/2024.03.13.584849 — cancer biology — Posted on 2024-03-13
2945 The Cyclin-Like Protein Spy1 Mediates Tumourigenic Potential of Triple Negative Breast Cancer
Fifield, B.-A.; Pecoraro, C.; Basilious, A.; Gramisteanu, C.; Mailloux, E.; Ferraiuolo, R.-M.; Porter, L. A.
10.1101/2024.03.11.584461 — cancer biology — Posted on 2024-03-13
2946 Metaplastic tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer
Salas-Escabillas, D. J.; Hoffman, M. T.; Moore, J. S.; Brender, S. M.; Wen, H.-J.; Benitz, S.; Davis, E. T.; Long, D.; Wombwell, A. M.; Steele, N. G.; Sears, R. C.; Matsumoto, I.; DelGiorno, K. E.; Crawford, H. C.
10.1101/2024.02.12.579982 — cancer biology — Posted on 2024-03-13
2948 Membrane Lipid Domains Modulate HCN Channels in Nociceptor DRG Neurons
Handlin, L. J.; Macchi, N. L.; Dumaire, N.; Salih, L.; McCommis, K. S.; Moutal, A.; Dai, G.
10.1101/2023.09.02.556056 — biophysics — Posted on 2024-03-13
2951 HPClas: A data-driven approach for identifying halophilic proteins based on catBoost
Shantong, H.; Zhikang, W.; Xiaoyu, W.; Yongfei, C.; Yun, T.; Zhuoqian, L.; Menghan, J.; Shihui, W.; wenya, W.; Guimin, Z.; Jiangning, S.
10.1101/2023.11.30.569348 — bioinformatics — Posted on 2024-03-13
2953 Dynamic culture of cerebral organoids using a pillar/perfusion plate for the assessment of developmental neurotoxicity
Acharya, P.; Shrestha, S.; Joshi, P.; Choi, N. Y.; Lekkala, V. K. R.; Kang, S.-Y.; Ni, G.; Lee, M.-Y.
10.1101/2024.03.11.584506 — bioengineering — Posted on 2024-03-13
2954 Development and application of GlycanDIA workflow for glycomic analysis
Xie, Y.; Liu, X.; Zhao, C.; Chen, S.; Wang, S.; Lin, Z.; Robison, F. M.; George, B. M.; Flynn, R. A.; Lebrilla, C. B.; Garcia, B. A.
10.1101/2024.03.12.584702 — biochemistry — Posted on 2024-03-13
2956 Sulfite oxidase deficiency causes persulfidation loss and H2S release
Fu, C.-Y.; Kohl, J. B.; Liebsch, F.; D`Andrea, D.; Mai, M.; Mellis, A. T.; Kouroussis, E.; Ditroi, T.; Santamaria-Araujo, J. A.; Yeo, S. Y.; Endepols, H.; Krizkov, M.; Kozich, V.; Barayeu, U.; Akaike, T.; Hennermann, J. B.; Nagy, P.; Filipovic, M.; Schwarz, G.
10.1101/2024.03.13.584820 — biochemistry — Posted on 2024-03-13
2958 Differences in Protein Capture by SP3 and SP4 Demonstrate Mechanistic Insights of Proteomics Clean-up Techniques
Conforti, J. M.; Ziegler, A. M.; Worth, C. S.; Nambiar, A. M.; Bailey, J. T.; Taube, J. H.; Gallagher, E. S.
10.1101/2024.03.13.584881 — biochemistry — Posted on 2024-03-13
2959 Anti-fungal recombinant psoriasin effectively inhibits Candida albicans growth on denture base
Lifshits, L. A.; Brohnshtein, E.; Attias, M.; Breuer, Y.; Cohen, A.; Gabay, M.; Sova, M.; Weinberg, E.; Zenziper, E.; Bar, D. Z.; Sterer, N.; Gal, M.
10.1101/2024.03.12.584579 — biochemistry — Posted on 2024-03-13
2960 Structural basis for Retriever-SNX17 assembly and endosomal sorting
Singla, A.; Boesch, D. J.; Fung, H. Y. J.; Ngoka, C.; Enriquez, A. S.; Song, R.; Kramer, D. A.; Han, Y.; Juneja, P.; Billadeau, D. D.; Bai, X.; Chen, Z.; Turer, E. E.; Burstein, E.; Chen, B.
10.1101/2024.03.12.584676 — biochemistry — Posted on 2024-03-13
2961 SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug discovery
Kremling, V.; Falke, S.; Fernandez-Garcia, Y.; Ehrt, C.; Kiene, A.; Klopprogge, B.; Scheer, T. E. S.; Barthels, F.; Middendorf, P.; Kuehn, S.; Guenther, S.; Rarey, M.; Chapman, H. N.; Oberthuer, D.; Sprenger, J.
10.1101/2024.03.13.583470 — biochemistry — Posted on 2024-03-13
2962 Thoughtful faces: inferring internal states across species using facial features
Tlaie, A.; Abd El Hay, M. Y.; Mert, B.; Taylor, R.; Ferracci, P. A.; Shapcott, K. A.; Glukhova, M.; Pillow, J. W.; Havenith, M. N.; Scholvinck, M.
10.1101/2024.01.24.577055 — animal behavior and cognition — Posted on 2024-03-13
2965 Development in context: interferon response networks regulate human fetal thymic epithelial cell differentiation
Mohammed, A.; Solomon, B.; Slepicka, P. F.; Hubka, K. M.; Nguyen, H. D.; Wang, W.; Arreola, M.; Chavez, M. G.; Yeh, C. Y.; Kim, D. K.; Winn, V. D.; Gifford, C. A.; Kedlian, V.; Park, J.-E.; Hollander, G. A.; Sebastiano, V.; Khatri, P.; Teichmann, S. A.; Gentles, A.; Weinacht, K. G.
10.1101/2022.10.02.510339 — developmental biology — Posted on 2024-03-13
2966 Cell surface morphology mimicking nano-bio platform for immune cell stimulation
Varghese, B.; Gonzalez-Navarro, J. A.; Guerra, V. L. P.; Faizulina, M.; Artemieva, D.; Chum, T.; Ramakrishna, T. R. B.; Cebecauer, M.; Kovaricek, P.
10.1101/2024.01.23.576453 — cell biology — Posted on 2024-03-13
2967 Changes in the senescence profile and immune checkpoints in HIV-infected individuals after COVID-19
Crespo-Bermejo, C.; Brochado-Kith, O.; Grande-Garcia, S.; Lara-Aguilar, V.; Llamas-Adan, M.; Arca-Lafuente, S.; Martin-Carbonero, L.; de los Santos, I.; Jimenez Sousa, M. A.; Resino, S.; Berenguer, J.; Madrid, R.; Fernandez-Rodriguez, A.; Briz, V.
10.1101/2024.03.12.584682 — microbiology — Posted on 2024-03-13
2968 Detection of oat crown rust disease in Taiwan (2019-2021)
Ho, C.-Y.; Henningsen, E.; Chen, S.-T.; Ariyawansa, H. A.; Nazareno, E. C.; Sperschneider, J.; Dodds, P.; Riddle, J. M.; Kianian, S. F.; Figueroa, M.; Huang, Y.-F.
10.1101/2024.03.12.584714 — microbiology — Posted on 2024-03-13
2971 The Role of Ebola Virus VP24 Nuclear Trafficking Signals in Infectious Particle Production
Vogel, O. A.; Nafziger, E.; Sharma, A.; Pasolli, H. A.; Davey, R. A.; Basler, C. F.
10.1101/2024.03.13.584761 — microbiology — Posted on 2024-03-13
2972 The Structure of the Lujo Virus Spike Complex
Eilon-Ashkenazy, M.; Cohen-Dvashi, H.; Borni, S.; Shaked, R.; Calinsky, R.; Levy, K.; Diskin, R.
10.1101/2024.03.13.584793 — microbiology — Posted on 2024-03-13
2973 The multifunction Coxiella effector Vice stimulates macropinocytosis and interferes with the ESCRT machinery
Bienvenu, A.; Burette, M.; Cantet, F.; Gourdelier, M.; Swain, J. M.; Cazevieille, C.; Clemente, T.; Sadi, A.; Dupont, C.; Le Fe, M.; Bonetto, N.; Bordignon, B.; MURIAUX, D.; Gilk, S. D.; Bonazzi, M.; Martinez, E.
10.1101/2024.03.13.584753 — microbiology — Posted on 2024-03-13
2974 Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis
Nahas, K. L.; Connor, V.; Wijesinghe, K. J.; Barrow, H. G.; Dobbie, I. M.; Harkiolaki, M.; Graham, S. C.; Crump, C. M.
10.1101/2024.03.13.584906 — microbiology — Posted on 2024-03-13
2979 Root exudation and rhizosphere microbial recruitment are influenced by novel plant trait diversity in carrot genotypes
Anderson, H. M.; Cagle, G. A.; Majumder, E. L.- W.; Silva, E.; Dawson, J.; Simon, P.; Freedman, Z. B.
10.1101/2024.03.12.583384 — microbiology — Posted on 2024-03-13
2983 Phosphorylation of PLPPR3 membrane proteins as signaling integrator at neuronal synapses
Kroon, C.; Bareesel, S.; Kirchner, M.; Gimber, N.; Ranti, D.; Brosig, A.; Textoris-Taube, K.; Zolnik, T. A.; Mertins, P.; Schmoranzer, J.; Leondaritis, G.; Eickholt, B. J.
10.1101/2024.03.11.584206 — neuroscience — Posted on 2024-03-13
2988 Host evolution improves genetic circuit function in complex growth environments
Zhang, J. T.; Lezia, A.; Emmanuele, P.; Wu, M.; Olson, C. A.; Feist, A. T.; Hasty, J.
10.1101/2024.03.13.583595 — synthetic biology — Posted on 2024-03-13
2992 AlphaFold2 structures template ligand discovery
Lyu, J.; Kapolka, N.; Gumpper, R.; Alon, A.; Wang, L.; Jain, M.; Alvarez, X.; Sakamoto, K.; Kim, Y.; DiBerto, J.; Kim, K.; Tummino, T.; Huang, S.; Irwin, J.; Tarkhanova, O.; Moroz, Y.; Skiniotis, G.; Kruse, A.; Shoichet, B.; Roth, B.
10.1101/2023.12.20.572662 — pharmacology and toxicology — Posted on 2024-03-13
2994 Genome-wide association studies in a diverse strawberry collection unveil loci controlling agronomic and fruit quality traits
Munoz, P.; Roldan-Guerra, F. J.; Verma, S.; Ruiz-Velazquez, M.; Torreblanca, R.; Oiza, N.; Castillejo, C.; Sevilla, J. F. S.; Amaya, I.
10.1101/2024.03.11.584394 — plant biology — Posted on 2024-03-13
2995 A novel regulatory pathway recognizes and degrades transcripts with long 3' untranslated regions
Daly, C. W. P.; Kristjansdottir, K.; West, J. D.; Vu, L. T.; Fogarty, E. A.; Geissler, R.; McDermott, C.; Venkataramany, A.; Grimson, A.
10.1101/2024.03.11.584429 — genetics — Posted on 2024-03-13
2996 Comprehensive analysis of RNA-chromatin, RNA- and DNA-protein interactions
Khlebnikov, D. A.; Nikolskaya, A. A.; Zharikova, A. A.; Mironov, A. A.
10.1101/2024.03.13.584417 — bioinformatics — Posted on 2024-03-13
3000 Environmental DNA as a complementary tool for biodiversity monitoring: A multi-technique and multi-trophic approach to investigate cetacean distribution and feeding ecology
Afonso, L.; Costa, J.; Correia, A. M.; Valente, R.; Lopes, E.; Tomasino, M. P.; Gil, A.; Oliveira-Rodrigues, C.; Sousa-Pinto, I.; Lopez, A.; Magalhaes, C.
10.1101/2024.03.11.584480 — ecology — Posted on 2024-03-13
3001 Coupling hydrodynamic drifting simulations and seasonal demographics to forecast the occurrence of jellyfish blooms
Cant, J.; Jones, O. R.; Ellingson, I.; Laverick, J. H.; Majaneva, S.; Dierking, J.; Aberle, N.; Javidpour, J.
10.1101/2024.03.11.584451 — ecology — Posted on 2024-03-13
3002 Single Cell MALDI-MS Imaging of Lipids and Proteins in Senescent Fibroblasts
Sekera, E. R.; Rosas, L.; Holbrook, J. H.; Angeles, Q. D.; Khaliullin, T.; Rojas, M.; Mora, A. L.; Hummon, A. B.
10.1101/2024.03.13.584140 — biochemistry — Posted on 2024-03-13
3003 PrgE: an OB-fold protein from plasmid pCF10 with striking differences to prototypical bacterial SSBs
Breidenstein, A.; Lamy, A.; Bader, C. P. J.; Sun, W.-S.; Wanrooij, P. H.; Berntsson, R. P.-A.
10.1101/2024.03.13.584862 — biochemistry — Posted on 2024-03-13
3004 Single-Domain Antibody-Based Protein Degrader for Synucleinopathies
Jiang, Y.; Lin, Y.; Tetlow, A. M.; Pan, R.; Ji, C.; Kong, X.-P.; Congdon, E. E.; Sigurdsson, E. M.
10.1101/2024.03.11.584473 — neuroscience — Posted on 2024-03-13
3007 Drosophila appear resistant to trans-synaptic tau propagation
Catterson, J. H.; Mouofo, E. N.; Lopez De Toledo Soler, I.; Lean, G.; Dlamini, S.; Liddell, P.; Voong, G.; Katsinelos, T.; Wang, Y.-C.; Schoovaerts, N.; Verstreken, P.; Spires-Jones, T. L.; Durrant, C. S.
10.1101/2024.03.11.584446 — neuroscience — Posted on 2024-03-13
3008 Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis
Vegting, Y.; Jongejan, A.; Neele, A. E.; Claessen, N.; Sela, G.; Prange, K. H.; Kers, J.; Roelofs, J. J.; van der Heijden, J. W.; de Boer, O. J.; Remmerswaal, E. B.; Vogt, L.; Bemelman, F. J.; de Winther, M. P.; Moerland, P. D.; Hilhorst, M. L.
10.1101/2024.03.13.584866 — immunology — Posted on 2024-03-13
3011 Synthesis of geometrically realistic and watertight neuronal ultrastructure manifolds for in silico modeling
Abdellah, M.; Foni, A.; Garcia Cantero, J. J.; Roman Guerrero, N.; Boci, E.; Fleury, A.; Coggan, J. S.; Keller, D.; Planas, J.; Courcol, J.-D.; Khazen, G.
10.1101/2024.03.11.584388 — neuroscience — Posted on 2024-03-13
3012 The Pannexin-1 N-terminal Helix Gates a Switch between Ion Conductance and Anandamide Transport
Anderson, C. L.; Weiilnger, N. L.; Visser, F.; Nielsen, A. C.; Boyce, A. K.; Thompson, R. J.
10.1101/2024.03.11.584466 — neuroscience — Posted on 2024-03-13
3013 Electrophysiological signatures of a developmental delay in a stem cell model of KCNQ2 developmental and epileptic encephalopathy
Rosa, F.; Theiss, S.; Krepp, S.; Loeffler, H.; Mendes, D.; Klingenstein, S.; Liebau, S.; Weckhuysen, S.; Alber, M.; Petrou, S.; Lerche, H.; Maljevic, S.; Wuttke, T. V.
10.1101/2024.03.13.584717 — neuroscience — Posted on 2024-03-13
3014 Individual trajectories for recovery of neocortical activity in disorders of consciousness
Tewarie, P.; Abeysuriya, R.; Panda, R.; Nunez, P.; Vitello, M. M.; van der Lande, G.; Gosseries, O.; Thibaut, A.; Laureys, S.; Deco, G.; Annen, J.
10.1101/2024.03.11.584433 — neuroscience — Posted on 2024-03-13
3016 Chronic IL-6 overproduction induces a tolerogenic response in aged mice after peripheral nerve injury
Manich, G.; Barbanti, R.; Peris, M.; Villacampa, N.; Almolda, B.; Gonzalez, B.; Castellano, B.
10.1101/2024.03.13.584805 — neuroscience — Posted on 2024-03-13
3017 A brainstem circuit for gravity-guided vertical navigation
Zhu, Y.; Gelnaw, H.; Auer, F.; Hamling, K. R.; Ehrlich, D. E.; Schoppik, D.
10.1101/2024.03.12.584680 — neuroscience — Posted on 2024-03-13
3018 Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease
Chen, O. Y.; Vu, D. T.; Diaz, C. S.; Bodelet, J. S.; Phan, H.; Allali, G.; Nguyen, V.-D.; Cao, H.; He, X.; Muller, Y.; Zhi, B.; Shou, H.; Zhang, H.; He, W.; Wang, X.; Munafo, M.; Trung, N. L.; Nagels, G.; Ryvlin, P.; Pantaleo, G.
10.1101/2024.03.11.584383 — neuroscience — Posted on 2024-03-13
3019 Evolutionary double-bind treatment using radiotherapy and NK cell-based immunotherapy in prostate cancer
Luddy, K. A.; West, J.; Robertson-Tessi, M.; Desai, B.; Burrsell, T. M.; Barrett, S.; O'Sullivan, J.; Marignol, L.; Gatenby, R.; Brown, J. S.; Anderson, A. R.; O'Farrelly, C.
10.1101/2024.03.11.584452 — cancer biology — Posted on 2024-03-13
3023 Expanding and enriching the LncRNA gene landscape using the GeneCaRNA database
Aggarwal, S.; Rosenblum, C.; Gould, M.; Ziman, S.; Barshir, R.; Zelig, O.; Golan, Y. G.; Iny-Stein, T.; Safran, M.; Pietrokovski, S.; Lancet, D.
10.1101/2024.03.11.584435 — bioinformatics — Posted on 2024-03-13
3025 Time-resolved oxidative signal convergence across the algae-embryophyte divide
Rieseberg, T. P.; Dadras, A.; Darienko, T.; Post, S.; Herrfurth, C.; Fuerst-Jansen, J. M.; Hohnhorst, N.; Petroll, R.; Rensing, S. A.; Proeschold, T.; de Vries, S.; Irisarri, I.; Feussner, I.; de Vries, J.
10.1101/2024.03.11.584470 — evolutionary biology — Posted on 2024-03-13
3026 "This training is bound for glory": selection by experimental evolution of a bacteriophage with expanded host-range and increased virulence
Maurin, A.; Vasse, M.; Zarate-Chaves, C.; breyton, C.; Bouzidi, S.; hayer, J.; Dainat, J.; Mesleard-Roux, M.; Weill, F.-X.; Bravo, I. G.; Feugier, A.; Froissart, R.
10.1101/2024.03.13.584857 — evolutionary biology — Posted on 2024-03-13
3028 Chemical inhibition of the integrated stress response impairs the ubiquitin-proteasome system
Xu, S.; Gierisch, M. E.; Barchi, E.; Poser, I.; Alberti, S.; Salomons, F. A.; Dantuma, N. P.
10.1101/2024.03.13.584747 — cell biology — Posted on 2024-03-13
3033 Cellular and circuit mechanisms underlying binocular vision
Honnuraiah, S.; Huang, H. H.- Y.; Ryan, W. J.; Broersen, R.; Connelly, W. M.; Stuart, G.
10.1101/2024.03.11.584536 — neuroscience — Posted on 2024-03-13
3034 The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β/-cells
Pan, C.; Liu, Y.; Wang, L.; Fan, W.-Y.; Ni, Y.; Zhang, X.; Wu, D.; Li, C.; Li, J.; Li, Z.; Liu, R.; Hu, C.
10.1101/2024.03.11.584397 — physiology — Posted on 2024-03-13
3036 The genomic trajectory of ovarian high grade serous carcinoma is determined in STIC lesions
Cheng, Z.; Ennis, D. P.; Lu, B.; Mirza, H. B.; Sokota, C.; Kaur, B.; Singh, N.; Le Saux, O.; Russo, G.; Giannone, G.; Tookman, L. A.; Krell, J.; McDermott, J.; Barnes, C.; McNeish, I. A.
10.1101/2024.03.11.584384 — cancer biology — Posted on 2024-03-13
3039 eATP/P2X7R axis drives nanoparticle induced neutrophil recruitment in the pulmonary microcirculation
Li, C.; Liu, Q.; Han, L.; Immler, R.; Rathkolb, B.; Secklehner, J.; Hrabe de Angelis, M.; Yildirim, A. O.; Nicke, A.; Carlin, L. M.; Sperandio, M.; Stoeger, T.; Rehberg, M.
10.1101/2024.03.11.584398 — immunology — Posted on 2024-03-13
3041 Setting Climate Targets: The Case of Higher Education and Research
Ligozat, A.-L.; Brun, C.; Demirdjian, B.; Gouget, G.; Jarde, E.; Mialon, A.; Mouronval, A.-S.; Pagani, L.; Vieu, L.
10.1101/2024.03.11.584380 — scientific communication and education — Posted on 2024-03-13
3042 Separate domains of the Arabidopsis ENHANCER OF PINOID drive its own polarization and recruit PIN1 to the plasma membrane
Torres, R.; Matthes, M.; Yun, N.; Luichtl, M.; Büschges, U.; Fiesselmann, B.; Strickland, B.; Lehnardt, M.
10.1101/2024.03.11.584374 — plant biology — Posted on 2024-03-13
3044 A neurometabolic signature in the frontal cortex predicts individual differences in effort-based decision-making
Barakat, A.; Clairis, N.; Brochard, J.; Pessiglione, M.; Godin, J.-P.; Cuenoud, B.; Xin, L.; Sandi, C.
10.1101/2024.01.23.576854 — neuroscience — Posted on 2024-03-13
3045 Spatial interactions modulate tumor growth and immune infiltration
Marzban, S.; Srivastava, S.; Kartika, S.; Bravo, R.; Safriel, R.; Zarski, A.; Anderson, A. R. A.; Chung, C. H.; Amelio, A. L.; West, J.
10.1101/2024.01.10.575036 — cancer biology — Posted on 2024-03-13
3051 Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats
Amen, A.; Yoo, R.; Fabra-Garcia, A.; Bolscher, J.; Stone, W. J. R.; Bally, I.; Dergan-Dylon, S.; Kucharska, I.; de Jong, R. M.; de Bruijni, M.; Bousema, T.; King, C. R.; MacGill, R. S.; Sauerwein, R. W.; Julien, J.-P.; Poignard, P.; Jore, M. M.
10.1101/2023.11.03.565335 — immunology — Posted on 2024-03-13
3052 BOLD Moments: modeling short visual events through a video fMRI dataset and metadata
Lahner, B.; Dwivedi, K.; Iamshchinina, P.; Graumann, M.; Lascelles, A.; Roig, G.; Gifford, A. T.; Pan, B.; Jin, S.; Ratan Murty, N. A.; Kay, K.; Oliva, A.; Cichy, R.
10.1101/2023.03.12.530887 — neuroscience — Posted on 2024-03-13
3053 Acoustic inspired brain-to-sentence decoder for logosyllabic language
Feng, C.; Cao, L.; Wu, D.; Zhang, E.; Wang, T.; Jiang, X.; Zhou, C.; Chen, J.; Wu, H.; Lin, S.; Hou, Q.; Yang, J.; Lin, C.-T.; Zhu, J.; Sawan, M.; Zhang, Y.
10.1101/2023.11.05.562313 — neuroscience — Posted on 2024-03-13
3054 Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination
Doran, P. R.; Fomin-Thunemann, N.; Tang, R. P.; Balog, D.; Zimmerman, B.; Kilic, K.; Martin, E. A.; Kura, S.; Fisher, H. P.; Chabbott, G.; Herbert, J.; Rauscher, B. C.; Jiang, J. X.; Sakadzic, S.; Boas, D. A.; Devor, A.; Chen, I. A.; Thunemann, M.
10.1101/2023.11.07.566086 — neuroscience — Posted on 2024-03-13
3058 NEMO: Improved and accurate models for identification of 6mA using Nanopore sequencing
Kulkarni, O. V.; Zaveri, L.; Singh, N. K.; Mathew, R. J.; Ara, S.; Garde, S.; Reddy, M.; Tallapaka, K. B.; Sowpati, D. T.
10.1101/2024.03.12.584205 — genomics — Posted on 2024-03-13
3059 Copy number variants underlie the major selective sweeps in insecticide resistance genes in Anopheles arabiensis from Tanzania.
Lucas, E. R.; Nagi, S. C.; Kabula, B.; Batengana, B.; Kisinza, W.; Egyir-Yawson, A.; Essandoh, J.; Dadzie, S.; Chabi, J.; Van't Hof, A. E.; Rippon, E. J.; Pipini, D.; Harding, N. J.; Dyer, N. A.; Clarkson, C. S.; Miles, A.; Weetman, D.; Donnelly, M. J.
10.1101/2024.03.11.583874 — genomics — Posted on 2024-03-13
3061 Identification of novel myelodysplastic syndromes prognostic subgroups by integration of inflammation, cell-type composition, and immune signatures in the bone marrow
Gerlevik, S.; Hama, S.; Seymen, N.; Mumtaz, W.; Thompson, I. R.; Jalili, S. R.; Kaya, D. E.; Iacoangeli, A.; Pellagatti, A.; Boultwood, J.; Napolitani, G.; Mufti, G. J.; Karimi, M. M.
10.1101/2024.03.11.584361 — genomics — Posted on 2024-03-13
3062 NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni
Suresh Kumar Meena Kumari, M.; Liu, P.; Jump, K.; Morales, Y.; Miller, E. A.; Shecter, I.; Stadecker, M. J.; Kalantari, P.
10.1101/2024.03.11.584371 — immunology — Posted on 2024-03-13
3067 Autoimmune antibody-induced neuronal hyperactivity triggers pathological Tau in IgLON5 disease
Askin, B.; Cordero Gomez, C.; Duong, S. L.-L.; Kilic, C.; Goihl, A.; Newman, A.; Wagner, J.; Thomas, V.; Lamberty, J.; Huebschmann, S.; Semenova, E.; Koertvelyessy, P.; Reinhold, D.; Kornau, H.-C.; Turko, P.; Neher, J. J.; Schmitz, D. G.; Rost, B. R.; Diez, L.; Pruess, H.; Wegmann, S.
10.1101/2024.03.10.584272 — neuroscience — Posted on 2024-03-13
3068 Redirecting DNA repair for efficient CRISPR-Cas-based gene targeting in tomato
Vu, T. V.; Nguyen, N. T.; Kim, J.; Vu, M. H.; Song, Y. J.; Tran, M. T.; Sung, Y. W.; Kim, J.-Y.
10.1101/2024.03.12.584635 — plant biology — Posted on 2024-03-13
3069 Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma
Wang, D.; Ritz, C.; Pierce, A.; Brunt, B.; Luo, Y.; Dahl, N.; Venkataraman, S.; Danis, E.; Kus, K.; Mazan, M.; Rzymski, T.; Veo, B.; Vibhakar, R.
10.1101/2024.03.08.584103 — cancer biology — Posted on 2024-03-13
3070 NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms
Koerber, R.-M.; Krollmann, C.; Cieslak, K.; Tregel, E.; Brümmendorf, T. H.; Koschmieder, S.; Griesshammer, M.; Gütgemann, I.; Brossart, P.; Skoda, R.; Kolbe, C. C.; Latz, E.; Wolf, D.; Teichmann, L. L.
10.1101/2024.03.09.583936 — cancer biology — Posted on 2024-03-13
3072 PRMT5 maintains tumor stem cells to promote pediatric high-grade glioma tumorigenesis
DeSisto, J.; Balakrishnan, I.; Knox, A.; Link, G.; Venkataraman, S.; Vibhakar, R.; Green, A. L.
10.1101/2024.03.12.583794 — cancer biology — Posted on 2024-03-13
3076 Geometric deep learning framework for de novo genome assembly
Vrcek, L.; Bresson, X.; Laurent, T.; Schmitz, M.; Kawaguchi, K.; Sikic, M.
10.1101/2024.03.11.584353 — bioinformatics — Posted on 2024-03-13
3078 Benchmarking clustering, alignment, and integration methods for spatial transcriptomics
Hu, Y.; Li, Y.; Xie, M.; Rao, M.; Shen, W.; Luo, C.; Qin, H.; Baek, J.; Zhou, X. M.
10.1101/2024.03.12.584114 — bioinformatics — Posted on 2024-03-13
3086 Astrocytes control quiescent NSC reactivation via GPCR signaling-mediated F-actin remodeling
Lin, K.-Y.; Mahekta, G.; Lin, J.; Ding, W. Y.; Huang, J.; Gao, Y.; Tan, Y. S.; Teng, X.; Low, S. L. C.; Kanchanawong, P.; Toyama, Y.; Wang, H.
10.1101/2024.03.11.584337 — developmental biology — Posted on 2024-03-13
3088 CB1 Cannabinoid Receptor Agonists Induce Acute Respiratory Depression in Awake Mice
Watkins, J. M.; Aradi, P.; Hahn, R.; Makriyannis, A.; Mackie, K.; Katona, I.; Hohmann, A. G.
10.1101/2024.03.12.584260 — neuroscience — Posted on 2024-03-13
3091 Heterogeneity of layer 4 in visual areas of rhesus macaque cortex
Guenther, D. M.; Batiuk, M. Y.; Petukhov, V.; De Oliveira, R.; Wunderle, T.; Buchholz, C. J.; Fries, P.; Khodosevich, K.
10.1101/2024.03.11.584345 — neuroscience — Posted on 2024-03-13
3092 REST and RCOR genes display distinct expression profiles in neurons and astrocytes using 2D and 3D human pluripotent stem cell models
Maksour, S.; Ng, N.; Hulme, A. J.; Miellet, S.; Engel, M.; Sanz Munoz, S.; Balez, R.; Rollo, B.; Finol-Urdaneta, R. K.; Ooi, L.; Dottori, M.
10.1101/2024.03.09.584254 — neuroscience — Posted on 2024-03-13
3093 Bayesian Optimization of Neurostimulation (BOONStim)
Oliver, L. D.; Jeyachandra, J.; Dickie, E. W.; Hawco, C.; Mansour, S.; Buchanan, R. W.; Malhotra, A. K.; Blumberger, D. M.; Deng, Z.-D.; Voineskos, A. N.
10.1101/2024.03.08.584169 — neuroscience — Posted on 2024-03-13
3101 Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting
Steinbrecht, D.; Minia, I.; Milek, M.; Meisig, J.; Bluethgen, N.; Landthaler, M.
10.1101/2024.03.11.584215 — systems biology — Posted on 2024-03-13
3102 Navigated range expansion promotes migratory culling
Zhang, Y.; Hu, Q.; Su, Y.; Chu, P.; Wei, T.; Yu, P.; Liu, C.; Fu, X.
10.1101/2024.03.09.584265 — systems biology — Posted on 2024-03-13
3103 Deepening biomedical research training: Community-Building Wellness Workshops for Post-Baccalaureate Research Education Program (PREP) Trainees
Cole, D.; Eneim, A. S.; White, C. J.; Eddings, C. R.; Beckett, M. Q.; Clark, V.; Jeffery, J.; Wimalasena, V. K.; Figueroa, A.; Rosado-Franco, J. J.; Alhariri, R.; Powell, B. H.; Washington, P. W.; Christensen, L. N.; Wilson, K. L.; Kavran, J. M.
10.1101/2024.03.10.584300 — scientific communication and education — Posted on 2024-03-13
3105 De novo genome assembly of Myricaria laxiflora provides insights into its molecular mechanisms under flooding stress
Weibo, X.; Linbao, L.; Guiyun, H.; Bicheng, D.; Huiyuan, C.; Xiaobo, M.; Haibo, Z.; Zhiqiang, X.; Jihong, L.; Zhen, Y.; Di, W.
10.1101/2024.03.09.584251 — plant biology — Posted on 2024-03-13
3106 Growth arrest is a DNA damage protection strategy in plants
Serrano-Mislata, A.; Hernandez-Garcia, J.; de Ollas, C.; Blanco-Tourinan, N.; Gomez-Cadenas, A.; Sablowski, R.; Alabadi, D.; Blazquez, M. A.
10.1101/2024.03.12.584648 — plant biology — Posted on 2024-03-13
3107 An array of Zymoseptoria tritici effectors suppress plant immune responses
Thynne, E.; Ali, H.; Seong, K.; Abukhalaf, M.; Guerreiro, M. A.; Flores-Nunez, V. M.; Hansen, R.; Salman, M.; Rudd, J. J.; Kanyuka, K.; Krasileva, K. V.; Kettles, G. J.; Stukenbrock, E. H.
10.1101/2024.03.12.584321 — plant biology — Posted on 2024-03-13
3110 Reduction in activity and abundance of mitochondrial electron transport chain supercomplexes in pulmonary hypertension-induced right ventricular dysfunction
Ma, W.; Zhang, P.; Vang, A.; Zimmer, A.; Huck, S.; Nicely, P.; Wang, E.; Mancini, T. J.; Owusu-Sarfo, J.; Cavarsan, C. F.; Belyvech, A. E.; Campbell, K. S.; Terentyev, D.; Choudhary, G.; Clements, R. T.
10.1101/2024.03.08.584016 — pathology — Posted on 2024-03-13
3113 Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation
NUNEZ, F. J.; Banerjee, K.; Mujeeb, A. A.; Mauser, A.; Tronrud, C. E.; Zhu, Z.; Taher, A.; Kadiyala, P.; Carney, S. V.; Garcia-Fabiani, M. B.; Comba, A.; Alghamri, M. S.; McClellan, B. L.; Faisal, S. M.; Nwosu, Z. C.; Hong, H. S.; Qin, T.; Sartor, M. A.; Ljungman, M.; Cheng, S.-Y.; Appelman, H. D.; Lowenstein, P. R.; Lahann, J.; Lyssiotis, C. A.; Castro, M.
10.1101/2024.03.08.584091 — cancer biology — Posted on 2024-03-13
3115 ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer
Moreno, P.; Ohara, Y.; Craig, A. J.; Liu, H.; Yang, S.; Zhang, L.; Panigrahi, G.; Dorsey, T. H.; Cawley, H.; Azizian, A.; Gaedcke, J.; Ghadimi, M.; Hanna, N.; Hussain, S. P.
10.1101/2024.03.12.584316 — cancer biology — Posted on 2024-03-13
3117 BET inhibitors as a therapeutic intervention in gastrointestinal gene signature-positive castration-resistant prostate cancer.
Shukla, S.; Li, D.; Nguyen, H.; Conner, J.; Bayshtok, G.; Cho, W. H.; Pachai, M.; Teri, N.; Campeau, E.; Attwell, S.; Trojer, P.; Ostrovnaya, I.; Gopalan, A.; Corey, E.; Chi, P.; Chen, Y.
10.1101/2024.03.09.584256 — cancer biology — Posted on 2024-03-13
3118 A knockoff calibration method to avoid over-clustering in single-cell RNA-sequencing
DenAdel, A.; Ramseier, M. L.; Navia, A. W.; Shalek, A. K.; Raghavan, S.; Winter, P. S.; Amini, A. P.; Crawford, L.
10.1101/2024.03.08.584180 — bioinformatics — Posted on 2024-03-13
3120 Automated Identification of Germline de novo Mutations in Family Trios: A Consensus-Based Informatic Approach
Shadrina, M.; Kalay, O.; Demirkaya-Budak, S.; LeDuc, C. A.; Chung, W. K.; Turgut, D.; Budak, G.; Arslan, E.; Semenyuk, V.; Davis-Dusenbery, B.; Seidman, C. E.; Yost, H. J.; Jain, A.; Gelb, B. D.
10.1101/2024.03.08.584100 — bioinformatics — Posted on 2024-03-13
3121 CytoSignal Detects Locations and Dynamics of Ligand-Receptor Signaling at Cellular Resolution from Spatial Transcriptomic Data
Liu, J.; Manabe, H.; Qian, W.; Wang, Y.; Gu, Y.; Chu, A. K. Y.; Gadhvi, G.; Song, Y.; Ono, N.; Welch, J. D.
10.1101/2024.03.08.584153 — bioinformatics — Posted on 2024-03-13
3122 A Spatial Omnibus Test (SPOT) for Spatial Proteomic Data
Samorodnitsky, S. N.; Campbell, K. M.; Ribas, A.; Wu, M. C.
10.1101/2024.03.08.584117 — bioinformatics — Posted on 2024-03-13
3126 Interpretable antibody-antigen interaction prediction by bridging structure to sequence
Liu, Y.; Nie, Z.; Chen, J.; Zheng, X.; Fu, J.; Liu, Z.; Liu, X.; Xu, F.; Huang, X.; Zhang, W.-B.; Ma, S.; Gao, W.; Tian, Y.
10.1101/2024.03.09.584264 — bioinformatics — Posted on 2024-03-13
3130 Local FK506 delivery induces osteogenesis in in vivo rat bone defect and rabbit spine fusion models
Harrer, J. A.; Fulton, T. M.; Sangadala, S.; Kaiser, J.; Devereaux, E. J.; Oliver, C.; Presciutti, S. M.; Boden, S. D.; Willett, N. J.
10.1101/2024.03.08.584163 — bioengineering — Posted on 2024-03-13
3134 Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models
Park, Y.-J.; Lu, T.-C.; Jackson, T.; Goodman, L. D.; Ran, L.; Chen, J.; Liang, C.-Y.; Harrison, E.; Ko, C.; Hsu, A.-L.; Yamamoto, S.; Qi, Y.; Bellen, H. J.; Li, H.
10.1101/2024.03.10.584317 — genetics — Posted on 2024-03-13
3135 Symmetry breaking and fate divergence during lateral inhibition in Drosophila
phan, m.-s.; Kim, J.-m.; picciotto, c.; couturier, l.; veits, n.; Mazouni, K.; schweisguth, f.
10.1101/2024.03.11.583933 — developmental biology — Posted on 2024-03-13
3136 Rejuvenation of aged oocyte through exposure to young follicular microenvironment
Wang, H.; Huang, Z.; Lee, Y.; Song, X.; Shen, X.; Shu, C.; Wu, L. H.; Pakkiri, L. S.; Lim, P. L.; Zhang, X.; Drum, C. L.; Zhu, J.; Li, R.
10.1101/2024.03.11.584343 — developmental biology — Posted on 2024-03-13
3138 Distinct tissue-dependent composition and gene expression of human fetal innate lymphoid cells
Rodahl, I. E.; Ivarsson, M. A.; Loh, L.; Mold, J. E.; Westgren, M.; Friberg, D.; Mjosberg, J.; Bjorkstrom, N. K.; Marquardt, N.; Nixon, D. F.; Michaelsson, J.
10.1101/2024.03.12.583977 — immunology — Posted on 2024-03-13
3139 An Amygdalar Oscillator Coordinates Cellular and Behavioral Rhythms
Liu, Q.; Xiong, J.; Kim, D. W.; Lee, S. S.; Bell, B. J.; Alexandre, C.; Blackshaw, S.; Latremoliere, A.; Wu, M. N.
10.1101/2024.03.08.584151 — neuroscience — Posted on 2024-03-13
3141 CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia
Deschamps, P.; Wacheux, M.; Gosseye, A.; Morabito, M.; Pages, A.; Lyne, A.-M.; Alfaro, A.; Rameau, P.; Imanci, A.; Chelbi, R.; Marchand, V.; Renneville, A.; Patnaik, M. M.; Lapierre, V.; Badaoui, B.; Wagner-ballon, O.; Berthon, C.; Braun, T.; Willekens, C.; Itzykson, R.; Fenaux, P.; Thepot, S.; Etienne, G.; Porteu, f.; elvira-matelot, e. M.; Droin, N.; Perie, L.; Laplane, L.; Solary, E.; Selimoglu-Buet, D.
10.1101/2024.03.08.583935 — cancer biology — Posted on 2024-03-13
3142 Sex Hormones Alter Pseudomonas aeruginosa Iron Acquisition and Virulence Factors
Ebrahim, H.; Bryan, N.; Collette, A.; Armstrong, S.; Bronowski, C.; Floyd, R.; Fothergill, J.
10.1101/2024.03.12.584604 — microbiology — Posted on 2024-03-13
3144 IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.
Szabo, G.; Joshi, R.; Brezani, V.; Mey, G. M.; Guixe-Muntet, S.; Ortega-Ribera, M.; Zhuang, Y.; Zivny, A.; Werneburg, S.; Gracia-Sancho, J.
10.1101/2024.03.08.582968 — neuroscience — Posted on 2024-03-13
3145 Border-zone cardiomyocytes and macrophages contribute to remodeling of the extracellular matrix to promote cardiomyocyte invasion during zebrafish cardiac regeneration
Constanty, F.; Wu, B.; Wei, K.-H.; Lin, I.-T.; Dallmann, J.; Guenther, S.; Lautenschlaeger, T.; Priya, R.; Lai, S.-L.; Stainier, D. Y. R.; Beisaw, A.
10.1101/2024.03.12.584570 — cell biology — Posted on 2024-03-13
3146 Phosphoproteomic analysis reveals the diversity of signaling behind ErbB inhibitor-induced phenotypes
Vaparanta, K. M.; Jokilammi, A.; Merilahti, J.; Orling, J.; Virtanen, N.; Sahlgren, C.; Elenius, K.; Paatero, I.
10.1101/2024.03.12.584564 — cell biology — Posted on 2024-03-13
3149 A randomized, controlled, two-center preclinical trial assessing the efficacy of a new benzodiazepine-dihydropyridine hybrid molecule (JM-20) in rodent models of ischemic stroke
Ramirez-Sanchez, J.; Rex, A.; McCann, S.; Schulze, D.; Wong-Guerra, M.; Fonseca-Fonseca, L. A.; Garcia-Alfonso, E.; Ramirez-Abreu, A.; Limonta, R.; Dopatka, M.; Mosch, L.; Nunez-Figueredo, Y.; Dirnagl, U.
10.1101/2024.03.08.584085 — pharmacology and toxicology — Posted on 2024-03-13
3150 From lichens to crops: Pathogenic potential of Pseudomonas syringae from Peltigera lichens is similar to world-wide epidemic strains
Ramirez Carrera, N.; Caullireau, E.; Sigurbjornsdottir, M. A.; Vandelle, E.; Vilhelmsson, O.; Morris, C. E.
10.1101/2023.11.30.569175 — microbiology — Posted on 2024-03-13
3151 Phage predation, disease severity and pathogen genetic diversity in cholera patients
Madi, N.; Cato, E. T.; Sayeed, M. A.; Creasy-Marrazzo, A.; Cuenod, A.; Islam, K.; Khabir, M. I. U.; Bhuiyan, M. T. R.; Begum, Y.; Freeman, E.; Vustepalli, A.; Brinkley, L.; Kamat, M.; Bailey, L. S.; Basso, K. B.; Qadri, F.; Khan, A. I.; Shapiro, B. J.; Nelson, E. J.
10.1101/2023.06.14.544933 — microbiology — Posted on 2024-03-13
3153 A high resolution model of the grapevine leaf morphospace predicts synthetic leaves
Chitwood, D. H.; Torres-Lomas, E.; Hadi, E. S.; Peterson, W. L. G.; Fischer, M. F.; Rogers, S. E.; He, C.; Acierno, M. G. F.; Azumaya, S.; Benjamin, S. W.; Chalise, D. P.; Chess, E. E.; Engelsma, A. J.; Fu, Q.; Jaikham, J.; Knight, B. M.; Kodjak, N. S.; Lengyel, A.; Munoz, B. L.; Patterson, J. T.; Rincon, S. I.; Schumann, F. L.; Shi, Y.; Smith, C. C.; St. Clair, M. K.; Sweeney, C. S.; Whitaker, P.; Wu, J.; Diaz-Garcia, L.
10.1101/2024.03.08.584086 — plant biology — Posted on 2024-03-13
3154 Human-in-the-loop approach to identify functionally important residues of proteins from literature
Vollmar, M.; Tirunagari, S.; Harrus, D.; Armstrong, D.; Gaborova, R.; Gupta, D.; Afonso, M. Q. L.; Evans, G. L.; Velankar, S.
10.1101/2024.03.09.583700 — bioinformatics — Posted on 2024-03-13
3159 callsync: an R package for alignment and analysis of multi-microphone animal recordings
Smeele, S. Q.; Tyndel, S. A.; Klump, B. C.; Alarcon-Nieto, G.; Aplin, L. M.
10.1101/2023.02.07.527470 — ecology — Posted on 2024-03-13
3160 An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration
Marefati, M.; Fernandez-Vallone, V.; Leprovots, M.; Vasile, G.; Libert, F.; Lefort, A.; Dinsart, G.; Weber, A.; Jetzer, J.; Garcia, M.-I.; Vassart, G.
10.1101/2024.03.11.584399 — developmental biology — Posted on 2024-03-13
3163 EasyGrid: A versatile platform for automated cryo-EM sample preparation and quality control
Gemin, O.; Armijo, V.; Hons, M.; Bissardon, C.; Linares, R.; Bowler, M. W.; Wolff, G.; Kovalev, K.; Babenko, A.; Salo, V. T.; Schneider, S.; Rossi, C.; Lecomte, L.; Deckers, T.; Lauzier, K.; Janocha, R.; Felisaz, F.; Sinoir, J.; Galej, W. P.; Mahamid, J.; Muller, C. W.; Eustermann, S.; Mattei, S.; Cipriani, F.; Papp, G.
10.1101/2024.01.18.576170 — molecular biology — Posted on 2024-03-13
3165 Arteriolar degeneration and stiffness in cerebral amyloid angiopathy are linked to β-amyloid deposition and lysyl oxidase.
Ventura-Antunes, L.; Nackenoff, A.; Romero-Fernandez, W.; Bosworth, A. M.; Prusky, A.; Wang, E.; Carvajal-Tapia, C.; Shostak, A.; Harmsen, H.; Mobley, B.; Maldonado, J.; Solopova, E.; Snider, J. C.; Merryman, W. D. D.; Lippmann, E.; Schrag, M.
10.1101/2024.03.08.583563 — neuroscience — Posted on 2024-03-13
3166 Not seeing the forest for the trees: Combination of path integration and landmark cues in human virtual navigation
Scherer, J.; Muller, M. M.; Unterbrink, P.; Meier, S.; Egelhaaf, M.; Bertrand, O. J. N.; Boeddeker, N.
10.1101/2023.10.25.563902 — neuroscience — Posted on 2024-03-13
3167 Human monocyte subtype expression of neuroinflammation and -regeneration-related genes is linked to age and sex
Tampe, J.; Monni, E.; Brogardh, E.; Palma-Tortosa, S.; Boiers, C.; Lindgren, A. G.; Kokaia, Z.
10.1101/2024.03.10.584323 — neuroscience — Posted on 2024-03-13
3170 Mechanisms of genomic instability dictate cytosolic DNA composition and dendritic cell mediated anti-tumor immunity
Mosley, S. R.; Chen, A.; Doell, D. N.; Choi, S.; Mowat, C.; Meier-Stephenson, F.; Meier-Stephenson, V.; Baker, K.
10.1101/2024.03.08.584184 — cancer biology — Posted on 2024-03-13
3171 Robust cytoplasmic partitioning by solving an intrinsic cytoskeletal instability
Rinaldin, M.; Kickuth, A.; Dalton, B.; Xu, Y.; Di Talia, S.; Brugues, J.
10.1101/2024.03.12.584684 — biophysics — Posted on 2024-03-13
3173 PIGOME: An Integrated and Comprehensive Multi-omics Database for Pig Functional Genomics Studies
Han, G.; Yang, P.; Zhang, Y.; Li, Q.; Fan, X.; Chen, R.; Yan, C.; Zeng, M.; Yang, Y.; Tang, Z.
10.1101/2024.03.10.583139 — bioinformatics — Posted on 2024-03-13
3174 Transcriptomic analysis of TGFβ-mediated fibrosis in primary human Tenon's fibroblasts
Pasvanis, Z.; Boynes, A.; Kong, R. C. K.; Chan, E. C.; Wong, R. C. B.; Fan Gaskin, J. C.
10.1101/2024.03.09.583791 — bioinformatics — Posted on 2024-03-13
3176 The conserved membrane-proximal domain of Sbh1/ Sec61β guides signal peptides into the Sec61 channel
Yadhanapudi, L.; Bhadra, P.; Barbieri, G.; Jung, M.; Lommel, M.; Helms, V.; Romisch, K.
10.1101/2024.03.12.584615 — biochemistry — Posted on 2024-03-13
3179 Social ageing can protect against infectious disease in a group-living primate
Siracusa, E. R.; Pavez-Fox, M. A.; Negron-Del Valle, J. E.; Phillips, D.; Platt, M. L.; Snyder-Mackler, N.; Higham, J. P.; Brent, L. J. N.; Silk, M. J.
10.1101/2024.03.09.584237 — animal behavior and cognition — Posted on 2024-03-13
3186 Cdon is required for organ Left-Right patterning via regulating DFCs migration and the sequential ciliogenesis
Deng, Z.; Chang, W.; Li, C.; Li, B.; Huang, S.; Huang, J.; Zhang, K.; Li, Y.; Liu, X.; Ran, Q.; Guo, Z.; Huang, S.
10.1101/2024.03.12.584572 — developmental biology — Posted on 2024-03-13
3190 Choroid plexus enlargement in acute neuroinflammation is tightly interrelated to the tyrosine receptor signalling
Luessi, F.; Schiffer, J.; Gonzalez-Escamilla, G.; Fleischer, V.; Engel, S.; Ciolac, D.; Koeck, T.; Wild, P. S.; Gruchot, J.; Ruck, T.; Othmann, A.; Bittner, S.; Meuth, S. G.; Zipp, F.; Stueve, O.; Groppa, S.
10.1101/2024.03.09.583615 — neuroscience — Posted on 2024-03-13
3194 LINC complex alterations are a hallmark of sporadic and familial ALS/FTD
Sirtori, R.; Gregoire, M. J.; Potts, E.; Collins, A.; Donatelli, L.; Fallini, C.
10.1101/2024.03.08.584123 — neuroscience — Posted on 2024-03-13
3201 Independent expansion, selection and hypervariability of the TBC1D3 gene family in humans
Eichler, E.; Guitart, X.; Porubsky, D.; Yoo, D.; Dougherty, M. L.; Dishuck, P. C.; Munson, K. M.; Lewis, A. P.; Hoekzema, K.; Knuth, J.; Chang, S.; Pastinen, T.
10.1101/2024.03.12.584650 — genetics — Posted on 2024-03-13
3202 Islands promote diversification within the silvereye clade: a phylogenomic analysis of a great speciator
Estandia, A.; Recalde, N. M.; Sendell-Price, A. T.; Potvin, D. A.; Robertson, B. C.; Clegg, S. M.
10.1101/2024.03.11.584438 — evolutionary biology — Posted on 2024-03-13
3205 Functional genetics reveals modulators of anti-microtubule drug sensitivity
Su, K.-C.; Radul, E.; Maier, N. K.; Tsang, M.-J.; Goul, C. S.; Moodie, B.; Keys, H. R.; Cheeseman, I. M.
10.1101/2024.03.12.584469 — cell biology — Posted on 2024-03-13
3209 Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells
Wang, J.-P.; Hung, C.-H.; Liou, Y.-H.; Liu, C.-C.; Yeh, K.-H.; Wang, K.-Y.; Lai, Z.-S.; Chatterjee, B.; Hsu, T.-C.; Lee, T.-L.; Shyu, Y.-C.; Hsiao, P.-W.; Chen, L.-Y.; Chuang, T.-J.; Yu, C.-H. A.; Liao, N.-S.; Shen, C.-K. J.
10.1101/2023.04.21.537849 — cancer biology — Posted on 2024-03-12
3211 Genomic context sensitizes regulatory elements to genetic disruption
Ordonez, R.; Zhang, W.; Ellis, G.; Zhu, Y.; Ashe, H. J.; Ribeiro-dos-Santos, A. M.; Brosh, R.; Huang, E.; Hogan, M. S.; Boeke, J. D.; Maurano, M. T.
10.1101/2023.07.02.547201 — genomics — Posted on 2024-03-12
3212 An octopamine-specific GRAB sensor reveals a monoamine relay circuitry that boosts aversive learning
Lv, M.; Cai, R.; Zhang, R.; Xia, X.; Li, X.; Wang, Y.; Wang, H.; Zeng, J.; Xue, Y.; Mao, L.; Li, Y.
10.1101/2024.03.09.584200 — neuroscience — Posted on 2024-03-12
3214 Defense-related callose synthase PMR4 promotes root hair callose deposition and adaptation to phosphate deficiency in Arabidopsis thaliana
Okada, K.; Yachi, K.; Nguyen, T. A. N.; Kanno, S.; Yasuda, S.; Tadai, H.; Tateda, C.; Lee, T.-H.; Nguyen, U.; Inoue, K.; Miyashima, S.; Hiruma, K.; Miwa, K.; Maekawa, T.; Notaguchi, M.; Saijo, Y.
10.1101/2023.07.05.547890 — plant biology — Posted on 2024-03-12
3215 3D culture of pancreatic cancer cells in vitro recapitulates an aberrant mitochondrial oxidative phosphorylation genotype observed in vivo
Treherne, J. M.; Kus, K.; Krzykawski, M. P.; Earnshaw, D. L.; Krzykawska, R.; Biesaga, B.; Statkiewicz, M.; Unrug-Bielawska, K.; Sandowska-Markiewicz, Z.; Mikula, M.; Alfaro, J. A.
10.1101/2024.03.08.583569 — cancer biology — Posted on 2024-03-12
3217 Sex-specific viability effects of mutations in Drosophila melanogaster
Melde, R. H.; Abraham, J. M.; Ugolini, M. R.; Castle, M. P.; Fjalstad, M. M.; Blumstein, D. M.; Sharp, N. P.
10.1101/2024.03.09.584240 — evolutionary biology — Posted on 2024-03-12
3220 Key link between iron and the size structure of three main mesoplanktonic groups (Crustaceans, Rhizarians, and colonial N2-fixers) in the Global Ocean.
Dugenne, M.; Corrales-Ugalde, M.; Luo, J.; Stemmann, L.; Irisson, J.-O.; Lombard, F.; O'Brien, T.; Stock, C.; Kiko, R.
10.1101/2024.03.08.584097 — ecology — Posted on 2024-03-12
3222 Resolved Genomes of Wastewater ESBL-Producing Escherichia coli and Metagenomic Analysis of Source Wastewater Samples
Cheney, C.; Johnson, J.; Ste.Marie, J. P.; Gacosta, K. Y. M.; Denlinger Drumm, N. B.; Jones, G.; Waite-Cusic, J.; Navab-Daneshmand, T.
10.1101/2024.03.12.584675 — microbiology — Posted on 2024-03-12
3223 Long-term evolution reveals the role of the circadian cycle in the environmental adaptation of cyanobacteria
Mendana, A.; Santos-Merino, M.; Gutierrez-Lanza, R.; Dominguez-Quintero, M.; Medina, J. M.; Gonzalez-Guerra, A.; Campa, V.; Ducos-Galand, M.; Lopez-Igual, R.; Volke, D. C.; Gugger, M.; Nikel, P. I.; Mazel, D.; de la Cruz, F.; Fernandez-Lopez, R.
10.1101/2024.03.12.584591 — microbiology — Posted on 2024-03-12
3224 Hematopoietic stem cell gene therapy improves outcomes in a clinically relevant mousemodel of Multiple Sulfatase Deficiency
Pham, V.; Tricoli, L.; Hong, X.; Wongkittichote, P.; Castruccio Castracani, C.; Guerra, A.; Schlotawa, L.; Adang, L. A.; Kuhs, A.; Cassidy, M. M.; Kane, O.; Tsai, E.; Presa, M.; Lutz, C. M.; Rivella, S. B.; Ahrens-Nicklas, R. C.
10.1101/2024.03.08.584099 — neuroscience — Posted on 2024-03-12
3227 Australian researchers' perceptions and experiences with stem cell registration.
Hu, M.; Santos, D.; Lopes, E.; Nicol, D.; Kurtz, A.; Mah, N.; Muller, S. C.; Ankeny, R. A.; Wells, C.
10.1101/2024.03.11.584334 — scientific communication and education — Posted on 2024-03-12
3229 Mutational Profiling of SARS-CoV-2 PLpro in human cells reveals requirements for function, structure, and drug escape
Wu, X.; Go, M.; Nguyen, J. V.; Kuchel, N. W.; Lu, B. G. C.; Lowes, K. N.; Calleja, D. J.; Mitchell, J. P.; Lessene, G.; Komander, D.; Call, M. E.; Call, M. J.
10.1101/2024.03.11.584210 — biochemistry — Posted on 2024-03-12
3231 Why models underestimate tropical forest productivity: a case study in West Africa
zhang-zheng, h.; Deng, X.; Stocker, B.; Ruijie, R.; Thomson, E.; Adu-Bredu, S.; Duah-Gyamfi, A.; Gvozdevaite, A.; Moore, S.; Oliveras Menor, I.; Prentice, I. C.; Malhi, Y.
10.1101/2024.03.08.584066 — ecology — Posted on 2024-03-12
3232 N-glycosylated molecules act as a co-precipitant in RNA purification
Kim, S.; Choi, Y.-g.; Janssen, K.; Bull, C.; Joshi, B. S.; Pomorski, A.; Raz, V.; Tanenbaum, M. E.; Miesen, P.; Li, Z.; Joo, C.
10.1101/2024.03.12.584655 — molecular biology — Posted on 2024-03-12
3234 Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay.
Zhang, Y.; Nersisyan, L.; Fuerst, E.; Alexopoulos, I.; Huch, S.; Bassot, C.; Garre, E.; Sunnerhagen, P.; Piazza, I.; Pelechano, V.
10.1101/2024.03.12.584696 — molecular biology — Posted on 2024-03-12
3235 Cooperative colonization of the host and pathogen dissemination involves stochastic and spatially structured expression of virulence traits
Lopez-Pagan, N.; Rufian, J. S.; Luneau, J.; Sanchez-Romero, M.-A.; Aussel, L.; van Vliet, S.; Ruiz-Albert, J.; Beuzon, C. R.
10.1101/2024.03.12.584633 — microbiology — Posted on 2024-03-12
3236 Root exudation and rhizosphere microbial recruitment are influenced by novel plant trait diversity in carrot genotypes
Anderson, H. M.; Cagle, G. A.; Majumder, E. L.- W.; Silva, E.; Dawson, J.; Simon, P.; Freedman, Z.
10.1101/2024.03.12.583384 — microbiology — Posted on 2024-03-12
3239 GABAergic amacrine cells balance biased chromatic information in the mouse retina
Korympidou, M. M.; Strauss, S.; Schubert, T.; Franke, K.; Berens, P.; Euler, T.; Vlasits, A.
10.1101/2024.03.08.584060 — neuroscience — Posted on 2024-03-12
3240 Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics
Dessalles, C. A.; Cuny, N.; Boutillon, A.; Salipante, P. F.; Babataheri, A.; Barakat, A. I.; Salbreux, G.
10.1101/2024.03.10.584287 — biophysics — Posted on 2024-03-12
3243 Integrated in vivo functional screens and multi-omics analyses identify alpha-2,3-sialylation as essential for melanoma maintenance
Agrawal, P.; Chen, S.; de Pablos, A.; Jame-Chenarboo, F.; Miera Saenz de Vega, E.; Darvishian, F.; Osman, I.; Lujambio, A.; Mahal, L. K.; Hernando, E.
10.1101/2024.03.08.584072 — cancer biology — Posted on 2024-03-12
3244 GFPrint™: A MACHINE LEARNING TOOL FOR TRANSFORMING GENETIC DATA INTO CLINICAL INSIGHTS
Sanz-Martin, G.; Migliore, D. P.; Gomez del Campo, P.; del Castillo-Izquierdo, J.; Dominguez, J. M.
10.1101/2024.03.08.584090 — bioinformatics — Posted on 2024-03-12
3247 A genetic perspective on the recent demographic history of Ireland and Britain
Shanmugam, A.; Merrigan, M.; O'Reilly, S.; Molloy, A. M.; Brody, L.; Hardiman, O.; McLaughlin, R. L.; Cavalleri, G. L.; Byrne, R. P.; Gilbert, E. H.
10.1101/2024.03.08.584042 — genetics — Posted on 2024-03-12
3249 Chloride intracellular channel 4 (CLIC4) is a global regulator of type 1 interferon signaling in Systemic Sclerosis (SSc) epithelial cells
Wasson, C. W.; Dibb, S. L.; Caballero Ruiz, B.; Clavane, E. M.; Wells, R.; Kakkar, V.; De Lorenzis, E.; Ross, R. L.; Bryon, J.; Derrett-Smith, E.; Denton, C. P.; Meakin, P. J.; Del Galdo, F.
10.1101/2024.03.08.583925 — immunology — Posted on 2024-03-12
3250 Using behavioral biomarkers to redefine epochs of spontaneous recovery following spinal cord injury
Eisdorfer, J. T.; Thackray, J. K.; Theis, T.; Vivinetto, A.; Ricci, M. T.; Lin, S.; Oputa, O.; Martinez, A. M.; Nacht, H. D.; Tschang, M.; Mahmood, M.; Tucker, A.; Bohic, M.; Pusuloori, S.; Zmoyro, L.; Kumar, S.; Abraira Lab Computational Group, ; Schachner, M.; Popovich, P.; Ferguson, A. R.; McTigue, D.; Tysseling, V. M.; Dulin, J.; Hollis, E.; Datta, S. R.; Abraira, V. E. G.
10.1101/2023.10.31.564826 — neuroscience — Posted on 2024-03-12
3252 Spatial Lipidomics Maps Brain Alterations Associated with Mild Traumatic Brain Injury
Leontyev, D.; Pulliam, A. N.; Ma, X.; Gaul, D. A.; LaPlaca, M. C.; Fernandez, F. M.
10.1101/2024.01.25.577203 — neuroscience — Posted on 2024-03-12
3253 Dynamin-2 Mutations Linked to Neonatal-onset Centronuclear Myopathy impair exocytosis and endocytosis in adrenal chromaffin cells.
Bayones, L.; Guerra-Fernandez, M. J.; Figuroa-Cares, C.; Gallo, L. I.; Alfonso-Bueno, S.; Baez-Matus, X.; Gonzalez-Jamett, A.; Cardenas, A. M.; Marengo, F. D.
10.1101/2024.03.07.583689 — neuroscience — Posted on 2024-03-12
3254 Preserved spontaneous mentalizing amid reduced intersubject variability in autism during a movie narrative
Mangnus, M.; Koch, S. B. J.; Cai, K.; Greidanus Romaneli, M.; Hagoort, P.; Basnakova, J.; Stolk, A.
10.1101/2024.03.08.583911 — neuroscience — Posted on 2024-03-12
3255 Circadian dynamics of the Zbtb14 protein in the ventral hippocampus are disrupted in epileptic mice
Guntan, I.; Ghestem, A.; Nazaruk, K.; Nizinska, K.; Olszewski, M.; Nowicka, D.; Bernard, C.; Lukasiuk, K.
10.1101/2024.03.07.583828 — neuroscience — Posted on 2024-03-12
3258 Chemotherapy-driven de novo Wnt pathway activation dictates a dynamic shift to a drug-tolerant state in breast cancer cells
Lluis, F.; Ellaithy, Y.; Abreu de Oliveira, W. A.; Pabba, A.; Qualizza, A.; Richard, F.; Athanasouli, P.; Luci, C. R.; De Wispelaere, W.; Mourao, L.; Hamer, S.; Moens, S.; De Jaime-Soguero, A.; Francesca Baietti, M.; Hutten, S. J.; Jonkers, J.; Sammut, S.-J.; Soenen, S. J.; Scheele, C. L.; Bruna, A.; Desmedt, C.; Annibali, D.
10.1101/2024.03.08.584051 — cancer biology — Posted on 2024-03-12
3259 Three-dimensional spatio-angular fluorescence microscopy with a polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM)
Chandler, T.; Guo, M.; Su, Y.; Chen, J.; Wu, Y.; Liu, J.; Agashe, A.; Fischer, R. S.; Mehta, S. B.; Kumar, A.; Baskin, T. I.; Jamouille, V.; Liu, H.; Swaminathan, V.; Nain, A.; Oldenbourg, R.; La Riviere, P.; Shroff, H.
10.1101/2024.03.09.584243 — biophysics — Posted on 2024-03-12
3260 A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs
Brown, C.; Ghosh, S.; McAllister, R.; Kumar, M.; Walker, G.; Sun, E.; Aman, T.; Panda, A.; Kumar, S.; Li, W. V.; Coleman, J.; Liu, Y.; Rothman, J. E.; Bhattacharyya, M.; Gupta, K.
10.1101/2024.02.10.579775 — biophysics — Posted on 2024-03-12
3263 Escape from X inactivation is directly modulated by levels of Xist non-coding RNA
Hauth, A.; Panten, J.; Kneuss, E.; Picard, C.; Servant, N.; Rall, I.; Perez-Rico, Y. A.; Clerquin, L.; Servaas, N.; Villacorta, L.; Jung, F.; Luong, C.; Chang, H. Y.; Zaugg, J. B.; Stegle, O.; Odom, D. T.; Loda, A.; heard, E.
10.1101/2024.02.22.581559 — developmental biology — Posted on 2024-03-12
3265 Interpreting single-cell messages in normal and aberrant hematopoiesis with the Cell Marker Accordion
Busarello, E.; Biancon, G.; Lauria, F.; Ibnat, Z.; Ramirez, C.; Tome, G.; Aass, K. R.; VanOudenhove, J. J.; Standal, T.; Viero, G.; Halene, S.; Tebaldi, T.
10.1101/2024.03.08.584053 — bioinformatics — Posted on 2024-03-12
3267 Generative interpolation and restoration of images using deep learning for improved 3D tissue mapping
Joshi, S.; Forjaz, A.; Sang Han, K.; Shen, Y.; Xenes, D.; Matelsky, J.; Wester, B.; Munoz-Barrutia, A.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.
10.1101/2024.03.07.583909 — bioinformatics — Posted on 2024-03-12
3268 SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition
Zhang, Q. E.; Lindenberger, J.; Parsons, R.; Thakur, B.; Parks, R.; Park, C. S.; Huang, X.; Sammour, S.; Janowska, K.; Spence, T. N.; Edwards, R. J.; Martin, M.; Williams, W. B.; Gobeil, S.; Montefiori, D. C.; Korber, B.; Saunders, K. O.; Haynes, B. F.; Haynes, B. F.; Henderson, R.; Acharya, P.
10.1101/2024.02.12.580004 — biochemistry — Posted on 2024-03-12
3269 De novo assembly and characterization of a highly degenerated ZW sex chromosome in the fish Megaleporinus macrocephalus
Borges, C. H. d. S.; Utsunomia, R.; Varani, A. M.; Uliano da Silva, M.; Guerra, L. V.; Butzge, A. J.; Gomez Agudelo, J. F.; Manso, S.; Freitas, M. V.; Ariede, R. B.; Mastrochirico-Filho, V. A.; Penaloza, C.; Barria, A.; Porto-Foresti, F.; Foresti, F.; Hattori, R. S.; Guiguen, Y.; Houston, R. D.; Hashimoto, D. T.
10.1101/2024.03.07.583869 — genomics — Posted on 2024-03-12
3271 Genomic consequences of isolation and inbreeding in an island dingo population
Leon-Apodaca, A. V.; Kumar, M.; del Castillo, A.; Conroy, G. C.; Lamont, R. W.; Ogbourne, S.; Cairns, K. M.; Borburgh, L.; Behrendorff, L.; Subramanian, S.; Szpiech, Z. A.
10.1101/2023.09.15.557950 — evolutionary biology — Posted on 2024-03-12
3272 Directional swimming patterns in jellyfish aggregations
Malul, D.; Berman, H.; Solodoch, A.; Tal, O.; Barak, N.; Mizrahi, G.; Berenshtein, I.; Toledo, Y.; Lotan, T.; Sher, D. J.; Shavit, U.; Lehahn, Y.
10.1101/2024.03.08.584080 — ecology — Posted on 2024-03-12
3273 Growing older, growing more diverse: sea turtles and epibiotic cyanobacteria
Kanjer, L.; Filek, K.; Mucko, M.; Zekan Lupic, M.; Frleta-Valic, M.; Gracan, R.; Bosak, S.
10.1101/2024.03.08.584065 — ecology — Posted on 2024-03-12
3274 Two opposing roles for Bmp signalling in the development of electrosensory lateral line organs
Campbell, A. S.; Minarik, M.; Franek, R.; Fucikova, M.; Havelka, M.; Gela, D.; Psenicka, M.; Baker, C. V. H.
10.1101/2024.03.07.583945 — developmental biology — Posted on 2024-03-12
3275 A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions
Fang, J.; Hatch, C. J.; Andrejecsk, J.; Van Trigt, W.; Juat, D. J.; Chen, Y.-H.; Matsumoto, S.; Lee, A. P.; Hughes, C. C.
10.1101/2024.03.11.584490 — cell biology — Posted on 2024-03-12
3284 DiDBiT-TMT: A novel method to quantify changes in the proteomic landscape induced by neural plasticity
Gamaleldin, M.; Yu, N.-K.; Diedrich, J.; Ma, Y.; Wienand, A.; McClatchy, D.; Nykjaer, A.; Nabavi, S.; Yates, J. R.
10.1101/2024.03.07.583889 — neuroscience — Posted on 2024-03-12
3285 The unexplored diversity of wild lupins provides rich genomic resources and insights into lupin evolution
Susek, K.; Franco, E.; Tomaszewska, M.; Kroc, M.; Jamil, H.; Tanwar, U.; Nelson, M. N.; Papa, R.; Delledonne, M.; Jackson, S. A.
10.1101/2024.03.07.583883 — plant biology — Posted on 2024-03-12
3286 Cell-type-specific nuclear morphology predicts genomic instability and prognosis in multiple cancer types
Abel, J.; Jain, S.; Rajan, D.; Padigela, H.; Leidal, K.; Prakash, A.; Conway, J.; Nercessian, M.; Kirkup, C.; Javed, S. A.; Biju, R.; Harguindeguy, N.; Shenker, D.; Indorf, N.; Sanghavi, D.; Egger, R.; Trotter, B.; Gerardin, Y.; Brosnan-Cashman, J. A.; Dhoot, A.; Montalto, M. C.; Parmar, C.; Wapinski, I.; Khosla, A.; Drage, M. G.; Yu, L.; Taylor-Weiner, A.
10.1101/2023.05.15.539600 — cancer biology — Posted on 2024-03-12
3287 Targeted Proteomics of Plasma Extracellular Vesicles Uncovers MUC1 as Combinatorial Biomarker for the Early Detection of High-grade Serous Ovarian Cancer
Cooper, T. T.; Dieters-Castator, D. Z.; Liu, J.; Siegers, G. M.; Veliz, L.; Pink, D.; Lewis, J. D.; Fu, Y.; Lagugne-Labarthet, F.; Steed, H.; Lajoie, G. A.; Postovit, L. M.
10.1101/2022.03.31.486596 — cancer biology — Posted on 2024-03-12
3291 SPARTA: Interpretable functional classification of microbiomes and detection of hidden cumulative effects.
Ruiz, B.; Belcour, A.; Blanquart, S.; Buffet-Bataillon, S.; Le Huerou-Luron, I.; Siegel, A.; Le Cunff, Y.
10.1101/2024.03.07.583888 — bioinformatics — Posted on 2024-03-12
3293 Autoencoder-transformed transcriptome improves genotype-phenotype association studies
Li, Q.; Bian, J.; Weeraman, J.; Leung, A.; Yang, G.; Chekouo, T.; Yan, J.; Wu, J.; Long, Q.
10.1101/2023.07.23.550223 — bioinformatics — Posted on 2024-03-12
3298 Loss of Bbs8 leads to cystic kidney disease in mice and affects tubulin acetylation through HDAC2
Kieckhoefer, E.; Matthiessen, P. A.; Ebert, L. K.; Klausen, C.; Wachten, D.; Benzing, T.; May-Simera, H. L.; Schermer, B.
10.1101/2024.03.07.583949 — genetics — Posted on 2024-03-12
3303 Establishing a method for the cryopreservation of viable peripheral blood mononuclear cells in the International Space Station
Ishii, H.; Endo, R.; Hamanaka, S.; Hidaka, N.; Miyauchi, M.; Hagiwara, N.; Miyao, T.; Yamamori, T.; Aiba, T.; Akiyama, N.; Akiyama, T.
10.1101/2024.03.12.584560 — cell biology — Posted on 2024-03-12
3304 Regulation of Interstitial Lung Diseases by Pulmonary Endothelial Cells via PLVAP
Zhang, X.; Jia, L.; Hou, R.; Zhao, Y.-a.; Zhang, L.; Tong, X.; Mo, Y.; Zhang, L.
10.1101/2024.03.12.584592 — cell biology — Posted on 2024-03-12
3309 Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans
Asiimwe, R.; Knott, B.; Greene, M. E.; Wright, E.; Bell, M.; Epstein, D.; Yates, S. D.; Cheung, M. D.; Gonzalez, M. V.; Fry, S.; Boydston, E.; Clevenger, S.; Locke, J. E.; George, J. F.; Burney, R.; Arora, N.; Duncan, V. E.; Richter, H. E.; Gunn, D.; Freud, A. G.; Little, S. C.; Porrett, P. M.
10.1101/2024.03.07.583906 — immunology — Posted on 2024-03-12
3310 The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness
Zeng, H.; Zhu, X.; Wu, Y.; Li, Y.; Zhou, X.; Watzlawik, J.; Chen, Y. M.; Raybuck, A.; Billadeau, D.; Shapiro, V.; Springer, W.; Sun, J.; Boothby, M. R.
10.1101/2024.02.26.582122 — immunology — Posted on 2024-03-12
3311 Differential predictive value of resident memory CD8+T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapy
Paolini, L.; Tran, T.; Corgnac, S.; VILLEMIN, J.-P.; Wislez, M.; Arrondeau, J.; Johannes, L.; Ulmer, J.; Vieillard, L.-V.; Pineau, J.; Gey, A.; Quiniou, V.; Barennes, P.; Pham, H. P.; Gruel, n.; Hasan, M.; Libri, V.; Mella, S.; de Percin, S.; Boudou-Rouquette, P.; Cremer, I.; Blons, h.; Leroy, K.; Laurent-Puig, P.; De Saint Basile, H.; Gibault, L.; Patrice, R.; Mami-Chouaib, F.; Goldwasser, F.; Fabre, E.; Damotte, D.; TARTOUR, E.
10.1101/2024.03.07.583820 — immunology — Posted on 2024-03-12
3313 Comparison of Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations
Lee, Y. J.; Syed, K.; Busquets, O.; Li, H.; Dunnack, J.; Sahagun, A.; Bateup, H.; Soldner, F.; Hockemeyer, D.; Rio, D.
10.1101/2024.02.28.582420 — neuroscience — Posted on 2024-03-12
3316 Spatially conserved pathoprotein profiling in the human suprachiasmatic nucleus in progressive Alzheimer disease stages
Son, G.; Mladinov, M.; Pereira, F.; Li, S. H.; Tu, C.-L.; Judge, G.; Yang, Y.; Suemoto, C.; Leite, R.; Paes, V.; Pasqualucci, C.; Jacob-Filho, W.; Spina, S.; Seeley, W.; Chang, W.; Neylan, T.; Grinberg, L. T.
10.1101/2024.03.07.584000 — neuroscience — Posted on 2024-03-12
3317 The heritability and structural correlates of brain entropy
Zhen, Y.; Yang, Y.; Zheng, Y.; Wang, X.; Liu, L.; Zheng, Z.; Zheng, H.; Tang, S.
10.1101/2024.03.07.583865 — neuroscience — Posted on 2024-03-12
3318 Distinct streams for supervised and unsupervised learning in the visual cortex
Zhong, L.; Baptista, S.; Gattoni, R.; Arnold, J.; Flickinger, D.; Stringer, C.; Pachitariu, M.
10.1101/2024.02.25.581990 — neuroscience — Posted on 2024-03-12
3319 Synaptic plasticity in human thalamocortical assembloids
Patton, M. H.; Thomas, K. T.; Bayazitov, I. T.; Newman, K. D.; Kurtz, N. B.; Robinson, C. G.; Ramirez, C. A.; Trevisan, A. J.; Bikoff, J. B.; Peters, S. T.; Pruett-Miller, S. M.; Jiang, Y.; Schild, A. B.; Nityanandam, A.; Zakharenko, S. S.
10.1101/2024.02.01.578421 — neuroscience — Posted on 2024-03-12
3320 Clinical factors associated with SFTS diagnosis and severity in cats
Osako, H.; Xu, Q.; Nabashima, T.; Balingit, J. C.; Nwe, K. M.; Yu, F.; Inoue, S.; Hayasaka, D.; Tun, M. M. N.; Morita, K.; Takamatsu, Y.
10.1101/2024.03.06.583784 — zoology — Posted on 2024-03-12
3322 Rice OsPLATZ3 controls ROS homeostasis by inhibiting ROS-Scavenging Activity during Tapetum Degeneration
Li, Y.; Wang, J.; Tang, F.; Li, L.; Cheng, X.; Sun, X.; Yu, S.; Xia, P.; Wang, Y.; Tong, M.; Cheng, L.
10.1101/2024.03.04.583394 — plant biology — Posted on 2024-03-12
3323 The Zinc Finger protein SlZFP2 is essential for tomato fruit locular tissue morphogenesis
Hoang, G.; Jorly, J.; Constantinescu, D.; Martin, P. G.; Gadin, S.; Mauxion, J.-P.; Bres, C.; Garcia, V.; Gonzalez, N.; Rothan, C.; Bertin, N.; Fernandez-Lochu, L.; Lemaire-Chamley, M.
10.1101/2024.03.07.582990 — plant biology — Posted on 2024-03-12
3324 Bridging fungal resistance and plant growth through constitutive overexpression of Thchit42 gene in Pelargonium graveolens
Rahman, L. U.; Khatoon, K.; Warsi, Z. I.; Singh, A.; Singh, K.; Khan, F.; Singh, P.; Shukla, R.; Verma, R.; Singh, M.; Verma, S. K.; Husain, Z.; Parween, G.; Singh, P.; Azmi, S.
10.1101/2024.03.07.583846 — plant biology — Posted on 2024-03-12
3326 Deletion of Robo4 worsens neuroinflammation and motor coordination in a mouse model of Alzheimer's disease
Cullen, A. E.; Winder, N.; Lee, B.; Krishna Kumaran, S.; Arora, N.; Wolf, J.; Woltjer, R.; Walker, A.
10.1101/2024.03.07.583582 — physiology — Posted on 2024-03-12
3330 miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma
Hong, E. S.; Wang, S. Z.; Ponti, A. K.; Hajdari, N.; Lee, J.; Mulkearns-Hubert, E. E.; Volovetz, J.; Kay, K. E.; Lathia, J.; Dhawan, A.
10.1101/2024.03.11.584443 — cancer biology — Posted on 2024-03-12
3331 Functional transcriptional signatures for tumor-type-agnostic phenotype prediction
Weistuch, C.; Murgas, K. A.; Zhu, J.; Norton, L.; Dill, K. A.; Tannenbaum, A. R.; Deasy, J. O.
10.1101/2023.04.12.536595 — cancer biology — Posted on 2024-03-12
3332 Competitive assembly resolves the stoichiometry of essential proteins in infectious HIV-1 virions.
Durden, H.; Preece, B.; Gallegos, R.; Saha, I.; MacArthur, B.; Petersen, A.; Peppel, W.; Saffarian, S.
10.1101/2024.03.10.584319 — biophysics — Posted on 2024-03-12
3336 Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions.
Leppert, A.; Jianhui, F.; Railaite, V.; Bohn Pessatti, T.; Morman, C.; Osterholz, H.; Maia, F. R. N. C.; Linder, M. B.; Rising, A.; Landreh, M.
10.1101/2024.03.12.584573 — biophysics — Posted on 2024-03-12
3338 Labeling Natural Killer cells with superparamagnetic iron oxide nanoparticles for detection by preclinical and clinical-scale magnetic particle imaging
Sehl, O. C.; Yang, Y.; Anjier, A. R.; Nevozhay, D.; Cheng, D.; Guo, K.; Fellows, B.; Mohtasebzadeh, A. R.; Mason, E. E.; Sanders, T.; Kim, P.; Trease, D.; Koul, D.; Goodwill, P. W.; Sokolov, K.; Wintermark, M.; Gordon, N.; Greve, J. M.; Gopalakrishnan, V.
10.1101/2024.03.08.583881 — biophysics — Posted on 2024-03-12
3341 Tipping-point transition from transient to persistent inflammation in pancreatic islets
Hansen, T. H.; Nielsen, P. Y.; Jensen, M. H.; Mandrup-Poulsen, T.; Trusina, A.
10.1101/2024.03.10.584271 — biophysics — Posted on 2024-03-12
3342 DNA-based ForceChrono Probes for Deciphering Single-Molecule Force Dynamics in Living Cells
Hu, Y.; Li, H.; Zhang, C.; Feng, J.; Wang, W.; Chen, W.; Yu, M.; Zhang, X.; Liu, Z.
10.1101/2024.03.09.584267 — biophysics — Posted on 2024-03-12
3346 Post-Translational Modifications Control Phase Transitions of Tau
Powell, W.; Nahum, M.; Pankratz, K.; Herlory, M.; Greenwood, J.; Poliyenko, D.; Holland, P.; Jing, R.; Biggerstaff, L.; Stowell, M.; Walczak, M.
10.1101/2024.03.08.583040 — biophysics — Posted on 2024-03-12
3347 Fatiguing Exercise Reduces Cellular Passive Young's Modulus in Human Vastus Lateralis Muscle
Privett, G. E.; Ricci, A. W.; David, L.; Needham, K. W.; Tan, Y. H.; Nakayama, K. H.; Callahan, D. M.
10.1101/2024.03.07.583989 — biophysics — Posted on 2024-03-12
3348 Comparative Pore Structure and Dynamics for Bacterial Microcompartment Shell Protein Assemblies in Sheets or Shells
Raza, S.; Sarkar, D.; Chan, L. J. G.; Mae, J.; Sutter, M.; Petzold, C. J.; Kerfeld, C. A.; Ralston, C. Y.; Gupta, S.; Vermaas, J. V.
10.1101/2024.03.12.584231 — biophysics — Posted on 2024-03-12
3351 Integrating spatial transcriptomics count data with Crescendo improves visualization and detection of spatial gene patterns
Millard, N.; Chen, J. H.; Palshikar, M. G.; Pelka, K.; Spurrell, M.; Price, C.; He, J.; Hacohen, N.; Raychaudhuri, S.; Korsunsky, I.
10.1101/2024.03.07.583997 — bioinformatics — Posted on 2024-03-12
3354 An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury
Fleischer, S.; Nash, T. R.; Tamargo, M. A.; Lock, R. I.; Venturini, G.; Morsink, M.; Li, V.; Lamberti, M. J.; Graney, P. L.; Liberman, M.; Kim, Y.; Zhuang, R. Z.; Whitehead, J.; Friedman, R. A.; SONI, R.; Seidman, J. G.; Seidman, C. E.; Geraldino-Pardilla, L.; Winchester, R.; Vunjak-Novakovic, G.
10.1101/2024.03.07.583787 — bioengineering — Posted on 2024-03-12
3356 A cryopreservation strategy for myoblast storage in paper-based scaffolds for inter-laboratory studies of skeletal muscle health
Rjaibi, S.; Jacques, E.; Ni, C.; Xu, B.; Kouthouridis, S.; Sitolle, J.; Lad, h.; Gulati, N.; Li, N. T.; Ahn, H.; Ginsberg, H.; Zhang, B.; Le-Grand, F.; Gilbert, P. M.; McGuigan, A. P.
10.1101/2024.03.07.583636 — bioengineering — Posted on 2024-03-12
3358 Phenylphenalenones and Linear Diarylheptanoid Derivatives are Biosynthesized via Parallel Routes in Musella lasiocarpa, the Chinese Dwarf Banana
Lyu, H.; Ernst, L.; Nakamura, Y.; Okamura, Y.; Koellner, T.; Luck, K.; Liu, B.; Chen, Y.; Beerhues, L.; Gershenzon, J.; Paetz, C.
10.1101/2024.03.11.584385 — biochemistry — Posted on 2024-03-12
3361 Exploring RNA modifications in infectious non-coding circular RNAs
Vopalensky, P.; Skriba, A.; Chiumenti, M.; Duricekova, L.; Simonova, A.; Luksan, O.; Di Serio, F.; Navarro, B.; Cahova, H.
10.1101/2024.03.12.584625 — biochemistry — Posted on 2024-03-12
3364 Inference of Transcriptional Regulation From STARR-seq Data
Safaeesirat, A.; Taeb, H.; Tekoglu, E.; Morova, T.; Lack, N.; Emberly, E.
10.1101/2024.03.06.583826 — genomics — Posted on 2024-03-12
3365 IQCH regulates spermatogenesis by interacting with CaM to promote the expression of RNA-binding proteins
Ruan, T.; Zhou, R.; Yang, Y.; Guo, J.; Jiang, C.; Wang, X.; Shen, G.; Dai, S.; Chen, S.; Shen, Y.
10.1101/2023.06.23.546221 — genetics — Posted on 2024-03-12
3377 cGAS-STING is responsible for aging of telomerase deficient zebrafish.
Serifoglu, N.; Allavena, G.; Bastos-Lopes, B.; Marzullo, M.; Bousounis, P.; Trompouki, E.; Ferreira, M. G.
10.1101/2024.03.11.584360 — cell biology — Posted on 2024-03-12
3379 DetectEV: a functional enzymatic assays to predict the potency of extracellular vesicles
Adamo, G.; Picciotto, S.; Gargano, P.; Paterna, A.; Rao, E.; Raccosta, S.; Romancino, D. P.; Ghersi, G.; Manno, M.; Salamone, M.; Bongiovanni, A.
10.1101/2023.10.24.563745 — cell biology — Posted on 2024-03-12
3380 Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation
Black, E. M.; Ramirez Parrado, C. A.; Trier, I.; Li, W. V.; Joo, Y. K.; Pichurin, J.; Liu, Y.; Kabeche, L.
10.1101/2024.03.08.584115 — cell biology — Posted on 2024-03-12
3381 Cytokine and Chemokine Receptor Profiles in Adipose Tissue Vasculature Unravel Endothelial Cell Responses in HIV
Obare, L. M.; Priest, S.; Ismael, A.; Mashayekhi, M.; Zhang, X.; Stolze, L.; Sheng, Q.; Vue, Z.; Neikirk, K.; Beasley, H.; Gabriel, C.; Temu, T.; Gianella, S.; Mallal, S.; Koethe, J.; Hinton, A.; Bailin, S.; Wanjalla, C. N.
10.1101/2024.03.10.584280 — cell biology — Posted on 2024-03-12
3384 DERIVATION OF ELEPHANT INDUCED PLURIPOTENT STEM CELLS
Appleton, E. M.; Hong, K.; Rodriguez-Caycedo, C.; Tanaka, Y.; Ashkenazy-Titelman, A.; Bhide, K.; Rasmussen-Ivey, C.; Ambriz-Pena, X.; Korover, N.; Bai, H.; Quieroz, A.; Nelson, J.; Rathod, G.; Knox, G.; Morgan, M.; Malviya, N.; Zhang, K.; McNutt, B.; Kehler, J.; Kowalczyk, A.; Bow, A.; McLendon, B.; Cantarel, B. L.; James, M.; Mason, C. E.; Gray, C.; Koehler, K.; Pearson, V.; Lamm, B.; Church, G.; Hysolli, E.
10.1101/2024.03.05.583606 — cell biology — Posted on 2024-03-12
3385 A Fully-Automated Senescence Test (FAST) for the high-throughput quantification of senescence-associated markers
Neri, F.; Takajjart, S. N.; Lerner, C. A.; Desprez, P.-Y.; Schilling, B.; Campisi, J.; Gerencser, A. A.
10.1101/2023.12.22.573123 — cell biology — Posted on 2024-03-12
3387 Bacterial strain nomenclature in the genomic era: Life Identification Numbers using a gene-by-gene approach
Palma, F.; Hennart, M.; Jolley, K. A.; Crestani, C.; Wyres, K. L.; Bridel, S.; Yeats, C. A.; Brancotte, B.; Raffestin, B.; David, S.; Lam, M. M. C.; Izdebski, R.; Passet, V.; Rodrigues, C.; Rethoret-Pasty, M.; Maiden, M. C. J.; Aanensen, D. M.; Holt, K. E.; Criscuolo, A.; Brisse, S.
10.1101/2024.03.11.584534 — microbiology — Posted on 2024-03-12
3388 Constitutive immune surveillance of nasal mucosa by three neutrophil subsets with distinct origin, phenotype, and function
Gonzalez, R. J.; Hanc, P.; Alvarez, D.; Kazer, S. W.; Messou, M.-A.; Mazo, I. B.; Matysiak Match, C.; Garg, R.; Helble, J. D.; Pallis, P.; Ende, R.; Basset, A.; Malley, R.; Derre, I.; Starnbach, M. N.; von Andrian, U. H.
10.1101/2024.03.06.583781 — immunology — Posted on 2024-03-12
3389 Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells
Cepika, A.-M.; Amaya, L.; Waichler, C.; Narula, M.; Mantilla, M. M.; Thomas, B. C.; Chen, P. P.; Freeborn, R. A.; Pavel-Dinu, M.; Nideffer, J.; Porteus, M.; Bacchetta, R.; Mueller, F.; Greenleaf, W. J.; Chang, H. Y.; Roncarolo, M. G.
10.1101/2024.03.07.582969 — immunology — Posted on 2024-03-12
3390 INGEsT: An Open-Source Behavioral Setup for Studying Self-motivated Ingestive Behavior and Learned Operant Behavior
Zhao, Z.; Xu, B.; Loomis, C. L.; Anthony, S. A.; McKie, I.; Srigiriraju, A.; Bolton, M.; Stern, S. A.
10.1101/2024.03.10.584229 — neuroscience — Posted on 2024-03-12
3392 Phosphorylation of PLPPR3 membrane proteins as signaling integrator at neuronal synapses
Kroon, C.; Bareesel, S.; Kirchner, M.; Gimber, N.; Ranti, D.; Brosig, A.; Textoris-Taube, K.; Zolnik, T. A.; Mertins, P.; Schmoranzer, J.; Leondaritis, G.; Eickholt, B.
10.1101/2024.03.11.584206 — neuroscience — Posted on 2024-03-12
3395 Neural mechanism of rebooting the unconsciousness caused by midazolam
Gu, L.; Shao, W.; Liu, L.; Xu, Q.; Wang, Y.; Gu, J.; Yang, Y.; Zhang, Z.; Wu, Y.; Shen, Y.; Yu, Q.; Lian, X.; Ma, H.; Zhang, Y.; Zhang, H.
10.1101/2023.03.20.533578 — neuroscience — Posted on 2024-03-12
3397 Human assembloid model of the ascending neural sensory pathway
Kim, J.-i.; Imaizumi, K.; Thete, M. V.; Hudacova, Z.; Jurjut, O.; Amin, N. D.; Scherrer, G.; Pasca, S. P.
10.1101/2024.03.11.584539 — neuroscience — Posted on 2024-03-12
3398 NeuralPlayground: A Standardised Environment for Evaluating Models of Hippocampus and Entorhinal Cortex
Domine, C. C. J.; Carrasco Davis, R. A.; Hollingsworth, L.; Sirmpilatze, N.; Tyson, A. L.; Jarvis, D.; Barry, C.; Saxe, A. M.
10.1101/2024.03.06.583699 — neuroscience — Posted on 2024-03-12
3399 The wake and sleep-modulating neurons of the lateral hypothalamic area demonstrate a differential pattern of degeneration in Alzheimers disease
Satpati, A.; Soloviev, A. V.; Pereira, F. L.; Mladinov, M.; Larsen, E.; Leite, R. E. P.; Suemoto, C. K.; Rodriguez, R. D.; Paes, V. R.; Walsh, C.; Spina, S.; Seeley, W. W.; Pasqualucci, C. A.; Filho, W. J.; Neylan, T. C.; Grinberg, L. T.
10.1101/2024.03.06.583765 — neuroscience — Posted on 2024-03-12
3401 Longevity of Implantable Silicon-ICs for Emerging Neural Applications: Evaluation of Bare Die and PDMS-Coated ICs After Accelerated Aging and Implantation Studies
Nanbakhsh, K.; Idil, A. S.; Lamont, C.; Ducso, C.; Akgun, O. C.; Horvath, D.; Toth, K.; Ulbert, I.; Mazza, F.; Constandinou, T.; Serdijn, W. A.; Vanhoestenberghe, A.; Donaldson, N.; Giagka, V.
10.1101/2024.03.06.583769 — neuroscience — Posted on 2024-03-12
3402 Modulation of pedunculopontine input to the basal ganglia relieves motor symptoms in Parkinsonian mice
Lin, C.; Ridder, M.; Zhong, J.; Albornoz, E. A.; Sedlak, P.; Xu, L.; Woodruff, T. M.; Chen, F.; Sah, P.
10.1101/2024.03.06.583786 — neuroscience — Posted on 2024-03-12
3403 Disentangling the spinal mechanisms of illusory heat and burning sensations in the Thermal Grill Illusion
Mitchell, A. G.; Fischer Ehmsen, J.; Elmstrom Christensen, D.; Stuckert, A.; Haggard, P.; Fardo, F.
10.1101/2023.08.24.554485 — neuroscience — Posted on 2024-03-12
3404 3D quantification of viral transduction efficiency in living human retinal organoids
Rogler, T. S.; Salbaum, K. A.; Sonntag, S. M.; James, R.; Shelton, E. R.; Brinkop, A. T.; Klopstock, T.; Babutzka, S.; Michalakis, S.; Serwane, F.
10.1101/2024.03.06.583795 — neuroscience — Posted on 2024-03-12
3405 The neural and computational architecture of feedback dynamics in mouse cortex during stimulus report
Ciceri, S.; Oude Lohuis, M. N.; Rottschafer, V.; Pennartz, C.; Avitabile, D.; van Gaal, S.; Olcese, U.
10.1101/2023.07.19.549692 — neuroscience — Posted on 2024-03-12
3406 NEK1 haploinsufficiency worsens DNA damage but not defective ciliogenesis in C9ORF72 patient-derived iPSC-motoneurons
Santangelo, S.; Invernizzi, S.; Sorce, M. N.; Casiraghi, V.; Peverelli, S.; Brusati, A.; Colombrita, C.; Ticozzi, N.; Silani, V.; Bossolasco, P.; Ratti, A.
10.1101/2024.03.07.582752 — neuroscience — Posted on 2024-03-12
3408 High-resolution perfusion imaging in rodents using pCASL at 9.4 T
Pires Monteiro, S.; Hirschler, L.; Barbier, E.; Figueiredo, P.; Shemesh, N.
10.1101/2024.03.07.583839 — neuroscience — Posted on 2024-03-12
3409 Cortical lipids containing choline mediate cannabinoid-induced cognitive improvement
Moreno-Rodriguez, M.; Martinez-Gardeazabal, J.; Bengoetxea de Tena, I.; Llorente-Ovejero, A.; Lombardero, L.; Gonzalez de San Roman, E.; Manuel, I.; Gimenez-Llort, L.; Rodriguez-Puertas, R.
10.1101/2024.03.07.583670 — neuroscience — Posted on 2024-03-12
3410 Second language learning in older adults modulates Stroop task performance and brain activation
Schultz, D. H.; Gansemer, A.; Allgood, K.; Gentz, M.; Secilmis, L.; Deldar, Z.; Savage, C. R.; Ghazi Saidi, L.
10.1101/2024.03.07.583963 — neuroscience — Posted on 2024-03-12
3411 Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation
Klokman, G.; Xu, Y.; Bond, K.; Wu, X.; Schustak, J.; Mandelbaum, J.; Twarog, M.; Han, H.; Paulina, M.-K.; Coble, M.; Hayden, C.; Galarneau, J.-R.; Qiu, Y.; Esterberg, R.; Huang, Q.; Saint-Geniez, M.; Aranda, J.; Bao, Y.
10.1101/2024.03.11.584455 — cell biology — Posted on 2024-03-12
3412 Nationwide genome surveillance of carbapenem-resistant Pseudomonas aeruginosa in Japan
Yano, H.; Hayashi, W.; Kawakami, S.; Aoki, S.; Anzai, E.; Zuo, H.; Kitamura, N.; Hirabayashi, A.; Kajihara, T.; Kayama, S.; Sugawara, Y.; Yahara, K.; Sugai, M.
10.1101/2023.12.17.572044 — microbiology — Posted on 2024-03-12
3417 SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition
Zhang, Q. E.; Lindenberger, J.; Parsons, R.; Thakur, B.; Parks, R.; Park, C. S.; Huang, X.; Sammour, S.; Janowska, K.; Spence, T. N.; Edwards, R. J.; Martin, M.; Williams, W. B.; Gobeil, S.; Montefiori, D. C.; Korber, B.; Saunders, K. O.; Haynes, B. F.; Haynes, B. F.; Henderson, R.; Acharya, P.
10.1101/2024.02.12.580004 — biochemistry — Posted on 2024-03-12
3419 Tbx1 haploinsufficiency causes brain metabolic and behavioral anomalies in adult mice which are corrected by vitamin B12 treatment
Caterino, M.; Paris, D.; Torromino, G.; Costanzo, M.; Flore, G.; Tramice, A.; Golini, E.; Mandillo, S.; Cavezza, D.; Angelini, C.; Ruoppolo, M.; Motta, A.; De Leonibus, E.; Baldini, A.; Illingworth, E.; Lania, G.
10.1101/2024.02.01.578212 — genetics — Posted on 2024-03-12
3420 Preventing multiple resistance above all: new insights for managing fungal adaptation
Ballu, A.; Ugazio, C.; Duplaix, C.; Noly, A.; Wullschleger, J.; Torriani, S. F. F.; Deredec, A.; Carpentier, F.; Walker, A.-S.
10.1101/2022.12.17.520869 — evolutionary biology — Posted on 2024-03-12
3421 Gene expression is the main driver of purifying selection in large penguin populations
Trucchi, E.; Massa, P.; Giannelli, F.; Latrille, T.; Fernandes, F. A. N.; Ancona, L.; Stenseth, N. C.; Ferrer Obiol, J.; Paris, J.; Bertorelle, G.; Le Bohec, C.
10.1101/2023.08.08.552445 — evolutionary biology — Posted on 2024-03-12
3423 Thymic epithelial organoids mediate T cell development
Hubscher, T.; Lorenzo-Martin, F.; Barthlott, T.; Tillard, L.; Langer, J.; Rouse, P.; Blackburn, C.; Hollander, G. C.; Lutolf, M.
10.1101/2024.03.05.583513 — developmental biology — Posted on 2024-03-12
3424 Reduced Filaggrin expression induces dysregulated intracellular signalling in atopic eczema
Hughes, A. J.; Coppock, L. E.; Tachie-Menson, T.; Thomas, B. R.; Dewan, P.; Doykov, I.; Mills, K.; O'Toole, E. A.; O'Shaughnessy, R. F.
10.1101/2024.03.11.584344 — cell biology — Posted on 2024-03-12
3426 Smad4 Loss in the Mouse Intestinal Epithelium Alleviates the Pathological Fibrotic Response to Injury in the Colon
Hashemi, Z.; Hui, T.; Wu, A.; Matouba, D.; Zokowski, S.; Nejati, S.; Lim, C.; Bruzzese, J.; Seabold, K.; Mills, C.; Lin, C.; Wrath, K.; Wang, H.; Wang, H.; Verzi, M. P.; Perekatt, A.
10.1101/2024.03.08.578000 — cell biology — Posted on 2024-03-12
3427 Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal women
Ulrich, N. D.; Vargo, A. H.; Ma, Q.; Shen, Y.-C.; Hannum, D. F.; Gurczynski, S. J.; Moore, B. B.; Schon, S.; Lieberman, R.; Shikanov, A.; Marsh, E. E.; Fazleabas, A. T.; Li, J. Z.; Hammoud, S. S.
10.1101/2024.03.07.583985 — cell biology — Posted on 2024-03-12
3428 Gliding motility of the diatom Craspedostauros australis correlates with the intracellular movement of raphid-specific myosins
Davutoglu, M. G.; Geyer, V. F.; Niese, L.; Soltwedel, J. R.; Zoccoler, M. L.; Haase, R.; Kroeger, N.; Diez, S.; Poulsen, N.
10.1101/2024.03.11.584054 — cell biology — Posted on 2024-03-12
3431 Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells
Myers, C. G.; Viswambharan, H.; Haywood, N.; Bridge, K.; Turvey, S. J.; Armstrong, T.; Lunn, L.; Meakin, P. J.; Clavane, E. M.; Beech, D. J.; Cubbon, R. M.; Wheatcroft, S. B.; McPhillie, M. J.; Issad, T.; Fishwick, C. W.; Kearney, M. T.; Simmons, K. J.
10.1101/2024.03.11.583535 — cell biology — Posted on 2024-03-12
3433 The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi
Weyer, Y.; Schwabl, S. I.; Tang, X.; Widerin, M. A.; Niedrist, V.; Tettamanti, M. G.; Weys, S.; Sarg, B.; Kremser, L.; Liedl, K. R.; Schmidt, O.; Teis, D.
10.1101/2024.03.11.584465 — cell biology — Posted on 2024-03-12
3434 Click-free imaging of carbohydrate trafficking in live cells using an azido photothermal probe
Xia, Q.; Perera, H. A.; Bolarinho, R.; Piskulich, Z. A.; Guo, Z.; Yin, J.; He, H.; Li, M.; Ge, X.; Cui, Q.; Ramstrom, O.; Yan, M.; Cheng, J.-X.
10.1101/2024.03.08.584185 — cell biology — Posted on 2024-03-12
3437 Establishment of an Inhalation Administration Noninvasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis
Tian, X.; Gao, Y.; Ma, W.; Zhang, J.; Ju, Y.; Ding, J.; Zeng, S.; Hameed, A.; Zhong, N.; Cook, G. M.; Hu, J.; zhang, T.
10.1101/2024.02.27.582260 — microbiology — Posted on 2024-03-12
3441 Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy
Zambo, B.; Edelweiss, E.; Morlet, B.; Negroni, L.; Pajkos, M.; Dosztanyi, Z.; Ostergaard, S.; Trave, G.; Laporte, J.; Gogl, G.
10.1101/2023.02.14.528471 — biochemistry — Posted on 2024-03-12
3443 Targeted protein degradation of the CPSF complex by benzoxaboroles through sumoylation
Zhang, N.; Samad, A.; Zahedifard, F.; Wall, R. J.; Horn, D.; Zoltner, M.; Field, M. C.
10.1101/2024.03.11.584402 — cell biology — Posted on 2024-03-12
3444 Non-endothelial expression of Endomucin in the mouse and human choroid
Brookins, E.; Serrano, S. E.; Yacu, G. S.; Finer, G.; Thomson, B. R.
10.1101/2024.03.08.584133 — cell biology — Posted on 2024-03-12
3445 A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions
Fang, J.; Hatch, C. J.; Andrejecsk, J.; Van Trigt, W.; Juat, D. J.; Chen, Y.-H.; Matsumoto, S.; Lee, A. P.; Hughes, C. C.
10.1101/2024.03.11.584490 — cell biology — Posted on 2024-03-12
3446 Distinct intersecting pathways link homolog pairing to initiation of meiotic chromosome synapsis
Blazickova, J.; Trivedi, S.; Bowman, R.; Geetha, S. S.; Subah, S.; Smolikove, S.; Jantsch, V.; Zetka, M.; Silva, N.
10.1101/2024.03.11.584447 — cell biology — Posted on 2024-03-12
3450 Fertilization-induced synergid cell death by RALF12-triggered ROS production and ethylene signaling
Chen, J.; Wang, H.; Wang, J.; Qu, W.; Zheng, X.; Fang, H.; Wang, S.; He, L.; Hao, S.; Dresselhaus, T.
10.1101/2024.03.10.584218 — cell biology — Posted on 2024-03-12
3451 Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production
Nobe, M.; Maruzuru, Y.; Takeshima, K.; Maeda, F.; Kusano, H.; Yoshimura, R.; Nishiyama, T.; Park, H.; Kozaki, Y.; Iwami, S.; Koyanagi, N.; Kato, A.; Natsume, T.; Adachi, S.; Kawaguchi, Y.
10.1101/2023.06.07.544155 — microbiology — Posted on 2024-03-12
3453 Whole-Brain Causal Discovery Using fMRI
Arab, F.; Ghassami, A.; Jamalabadai, H.; Peters, M. A. K.; Nozari, E.
10.1101/2023.08.12.553067 — neuroscience — Posted on 2024-03-12
3454 Prior probability cues bias sensory encoding with increasing task exposure
Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.
10.1101/2023.07.15.549123 — neuroscience — Posted on 2024-03-12
3456 Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells
Wang, J.-P.; Hung, C.-H.; Liou, Y.-H.; Liu, C.-C.; Yeh, K.-H.; Wang, K.-Y.; Lai, Z.-S.; Chatterjee, B.; Hsu, T.-C.; Lee, T.-L.; Shyu, Y.-C.; Hsiao, P.-W.; Chen, L.-Y.; Chuang, T.-J.; Yu, C.-H. A.; Liao, N.-S.; Shen, C.-K. J.
10.1101/2023.04.21.537849 — cancer biology — Posted on 2024-03-12
3461 Layer 5 Martinotti cell activation reduces pyramidal cell population plasticity and improves fine motor function
Velica, A.; Malfatti, T.; Winne, J.; Ciralli, B.; Henriksson, K.; Nogueira, I.; Asimakidou, E.; Nascimento, G.; Leao, R.; Kullander, K.
10.1101/2024.03.10.584276 — neuroscience — Posted on 2024-03-12
3462 A shifting role of thalamocortical connectivity in the emergence of large-scale functional brain organization across early lifespan development
Park, S.; Haak, K. V.; Oldham, S.; Cho, H.; Byeon, K.; Park, B.-y.; Thomson, P.; Chen, H.; Gao, W.; Xu, T.; Valk, S. L.; Milham, M.; Bernhardt, B.; Di Martino, A.; Hong, S.-J.
10.1101/2024.03.11.584415 — neuroscience — Posted on 2024-03-12
3464 Monkeys have rhythnm
Rajendran, V. G.; Marquez, J. P.; Prado, L.; Merchant, H.
10.1101/2024.03.11.584468 — neuroscience — Posted on 2024-03-12
3466 Polyglutamylation of microtubules drives neuronal remodeling
Gavoci, A.; Zhiti, A.; Ruskov, M.; Magiera, M. M.; Wang, M.; Ziegler, K. A.; Hausrat, T. J.; Engelhardt, S.; Kneussel, M.; Balastik, M.; Janke, C.; Misgeld, T.; Brill, M. S.
10.1101/2024.03.11.584412 — cell biology — Posted on 2024-03-12
3467 MULTIMODAL GRADIENTS UNIFY LOCAL AND GLOBAL CORTICAL ORGANIZATION
Wang, Y.; Eichert, N.; Paquola, C.; Rodriguez-Cruces, R.; DeKraker, J.; Royer, J.; Cabalo, D. G.; Auer, H.; Ngo, A.; Leppert, I.; Tardif, C. L.; Rudko, D. A.; Amunts, K.; Smallwood, J.; Evans, A. C.; Bernhardt, B. C.
10.1101/2024.03.11.583969 — neuroscience — Posted on 2024-03-12
3469 Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell Fusion
Li, P.; Liu, Y.; Faraone, J.; Hsu, C. C.; Chamblee, M.; Zheng, Y.-M.; Carlin, C.; Bednash, J. S.; Horowitz, J. C.; Mallampalli, R. K.; Saif, L. J.; Oltz, E. M.; Jones, D.; Li, J.; Gumina, R. J.; Liu, S.-L.
10.1101/2024.03.11.583978 — microbiology — Posted on 2024-03-11
3470 Exploring the therapeutic potential of defective interfering particles in reducing the replication of SARS-CoV-2
Locke, M.; Grebennikov, D.; Sazonov, I.; Lopez-Garcia, M.; Loguinova, M.; Meyerhan, A.; Bocharov, G.; Molina-Paris, C.
10.1101/2024.03.11.584367 — microbiology — Posted on 2024-03-11
3474 Staphylococcus aureus Persistence in Osteocytes: Weathering the Storm of Antibiotics and Autophagy/Xenophagy
Gunn, N. J.; Zelmer, A. R.; Kidd, S. P.; Solomon, L. B.; Yang, D.; Roscioli, E.; Atkins, G. J.
10.1101/2023.10.27.564475 — microbiology — Posted on 2024-03-11
3475 A continuum of CD4+ T cell 'help' defines 1 Memory B cell fate
Pritchard, G. H.; Krishnamurty, A. T.; Rodda, L.; McDougal, C.; Shehata, L.; Pepper, M.
10.1101/564351 — immunology — Posted on 2024-03-11
3478 High Frequency Terahertz Stimulation Alleviates Neuropathic Pain by Inhibiting the Pyramidal Neuron Activity in the Anterior Cingulate Cortex of mice
Peng, W.; Wang, P.; Tan, C.; Zhao, H.; Chen, K.; Si, H.; Tian, Y.; Lou, A.; Zhu, Z.; Yuan, Y.; Wu, K.; Chang, C.; Wu, Y.; Chen, T.
10.1101/2024.03.06.583763 — neuroscience — Posted on 2024-03-11
3479 Sleep need driven oscillation of glutamatergic synaptic phenotype
Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.
10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-03-11
3481 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures
Perrault, A. A.; Kebets, V.; Kuek, N. M. Y.; Cross, N. E.; Tesfaye, R.; Pomares, F. B.; Li, J.; Chee, M. W. L.; Dang Vu, T. T.; Yeo, B. T. T.
10.1101/2024.02.15.580583 — neuroscience — Posted on 2024-03-11
3482 Distributed network flows generate localized category selectivity in human visual cortex
Cocuzza, C. V.; Sanchez-Romero, R.; Ito, T.; Mill, R. D.; Keane, B. P.; Cole, M. W.
10.1101/2022.02.19.481103 — neuroscience — Posted on 2024-03-11
3483 Comparison of Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations
Lee, Y. J.; Syed, K.; Busquets, O.; Li, H.; Dunnack, J.; Sahagun, A.; Bateup, H.; Soldner, F.; Hockemeyer, D.; Rio, D.
10.1101/2024.02.28.582420 — neuroscience — Posted on 2024-03-11
3490 Integrative Co-Registration of Elemental Imag-ing and Histopathology for Enhanced Spatial Multimodal Analysis of Tissue Sections through TRACE
Lu, Y.; Steiner, R.; Han, S.; Srivastava, A.; Shaik, N.; Chan, M.; Diallo, A.; Punshon, T.; Jackson, B.; Kolling, F.; Vahdat, L.; Vaickus, L.; Marotti, J.; Ho, S.; Levy, J.
10.1101/2024.03.06.583819 — bioinformatics — Posted on 2024-03-11
3492 Structural and biophysical characterisation of ubiquitin variants that specifically inhibit the ubiquitin conjugating enzyme Ube2d2
McAlpine, J. M.; Zhu, J.; Pudjihartono, N.; Teyra, J.; Currie, M. J.; Dobson, R. C.; Sidhu, S. S.; Day, C. L.; Middleton, A. J.
10.1101/2024.03.10.583603 — biochemistry — Posted on 2024-03-11
3497 Microbial Response to Natural Disturbances: Rare Biosphere often plays a role
Zhao, J.; Brandt, G.; Wang, Z.; Hunt, D. E.; Rodriguez-R, L. M.; Hatt, J. K.; Konstantinidis, K. T.
10.1101/2024.03.06.583742 — ecology — Posted on 2024-03-11
3502 Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan
Anderson, M. J.; Hayward, A. N.; Smiley, A. T.; Shi, K.; Pawlak, M. R.; Aird, E. J.; Grant, E.; Greenberg, L.; Aihara, H.; Ulens, C.; Evans, R. L.; Gordon, W. R.
10.1101/2022.04.04.487063 — biochemistry — Posted on 2024-03-11
3503 EpicTope: narrating protein sequence features to identify non-disruptive epitope tagging sites
Zinski, J.; Chung, H.; Joshi, P.; Warrick, F.; Berg, B. D.; Glova, G.; McGrail, M. A.; Balciunas, D.; Friedberg, I.; Mullins, M. C.
10.1101/2024.03.03.583232 — developmental biology — Posted on 2024-03-11
3504 Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells
Balestrini, P. A.; Abdelbaki, A.; McCarthy, A.; Devito, L.; Senner, C. E.; Chen, A. E.; Munusamy, P.; Blakeley, P.; Elder, K.; Snell, P.; Christie, L.; Serhal, P.; Odia, R. A.; Sangrithi, M.; Niakan, K. K.; Fogarty, N. M.
10.1101/2021.08.18.456785 — developmental biology — Posted on 2024-03-11
3509 Multiple levels of transcriptional regulation control glycolate metabolism in Paracoccus denitrificans
Schada von Borzyskowski, L.; Hermann, L.; Kremer, K.; Barthel, S.; Pommerenke, B.; Glatter, T.; Paczia, N.; Bremer, E.; Erb, T. J.
10.1101/2024.03.11.584432 — microbiology — Posted on 2024-03-11
3511 Helicobacter pylori gamma-glutamyltransferase relates to proteomic adaptions important for gastric colonization
Fuchs, S.; Fiedler, M. K.; Heiduk, N.; Wanisch, A.; Debowski, A. W.; Marshall, B. J.; Sieber, S. A.; Gerhard, M.; Mejias-Luque, R.
10.1101/2024.03.11.584369 — microbiology — Posted on 2024-03-11
3512 FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria
Halte, M.; Andrianova, E. P.; Goosmann, C.; Chevance, F. F. V.; Hughes, K. T.; Zhulin, I. B.; Erhardt, M.
10.1101/2024.03.11.584431 — microbiology — Posted on 2024-03-11
3513 Human mobility and malaria risk in peri-urban and rural communities in the Peruvian Amazon
Gomez, J.; Grosso, A.; Guzman-Guzman, M.; Garcia Castillo, S.; Castro, M. C.; Torres, K.; Vinetz, J. M.; Gamboa, D.
10.1101/2024.03.11.584373 — microbiology — Posted on 2024-03-11
3515 Pre-trained molecular representations enable antimicrobial discovery
Olayo-Alarcon, R.; Amstalden, M. K.; Zannoni, A.; Bajramovic, M.; Sharma, C. M.; Brochado, A. R.; Rezaei, M.; Müller, C. L.
10.1101/2024.03.11.584456 — microbiology — Posted on 2024-03-11
3516 High-resolution analysis of the treated coeliac disease microbiome reveals increased inter-individual variability
Slager, J.; Simpson, H. L.; Gacesa, R.; Chen, L.; Gelderloos, J.; Maatman, A.; Wijmenga, C.; Zhernakova, A.; Fu, J.; Weersma, R.; Gonera, G.; Jonkers, I. H.; Withoff, S.
10.1101/2024.03.08.584098 — microbiology — Posted on 2024-03-11
3519 Synaptic connectome of the Drosophila circadian clock
Reinhard, N.; Fukuda, A.; Manoli, G.; Derksen, E.; Saito, A.; Möller, G.; Sekiguchi, M.; Rieger, D.; Helfrich-Förster, C.; Yoshii, T.; Zandawala, M.
10.1101/2023.09.11.557222 — neuroscience — Posted on 2024-03-11
3520 TRPC6 is a mechanosensitive channel essential for ultrasound neuromodulation in mammalian brain
Matsushita, Y. M.; Yoshida, K.; Yoshiya, M.; Shimizu, T.; Tsukamoto, S.; Takeuchi, Y.; Higuchi, M.; Shimojo, M.
10.1101/2024.03.06.583779 — neuroscience — Posted on 2024-03-11
3521 Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation
Marin, E. C.; Morris, B. J.; Stuerner, T.; Champion, A. S.; Krzeminski, D.; Badalamente, G.; Gkantia, M.; Dunne, C. R.; Eichler, K.; Takemura, S.-y.; Tamimi, I. F. M.; Fang, S.; Moon, S. S.; Cheong, H. S. J.; Li, F.; Schlegel, P.; Ahnert, S. E.; Berg, S.; FlyEM Project Team, ; Card, G. M.; Costa, M.; Shepherd, D.; Jefferis, G. S. X. E.
10.1101/2023.06.05.543407 — neuroscience — Posted on 2024-03-11
3524 Hypothalamic hormone deficiency enables physiological anorexia
Mohr, S. M.; Pra, R. D.; Platt, M. P.; Feketa, V. V.; Shanabrough, M.; Varela, L.; Kristant, A.; Cao, H.; Merriman, D. K.; Horvath, T. L.; Bagriantsev, S. N.; Gracheva, E. O.
10.1101/2023.03.15.532843 — physiology — Posted on 2024-03-11
3526 Glutamine addiction is targetable via altering splicing of nutrient sensors and epitranscriptome regulators
Bojko, J.; Kollareddy, M.; Szemes, M.; Bellamy, J.; Poon, E.; Moukachar, A.; Legge, D.; Vincent, E. E.; Jones, N.; Malik, S.; Greenhough, A.; Paterson, A.; Park, J. H.; Gallacher, K.; Chesler, L.; Malik, K.
10.1101/2024.02.28.582087 — cancer biology — Posted on 2024-03-11
3527 Functional multi-omics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma
Choudhry, P.; Kasap, C.; Patino Escobar, B.; Gugliemini, O.; Geng, H.; Sarin, V.; Kang, A.; Kishishita, A.; Rampersaud, S.; Sarah, L.; Lin, Y.-H. T.; Paranjape, N.; Ramkumar, P.; Marcoulis, M.; Wang, D.; Phojanakong, P.; Steri, V.; Hann, B.; Kampmann, M.; Wiita, A.
10.1101/2021.08.04.455165 — cancer biology — Posted on 2024-03-11
3528 SIGNAL-seq: Multimodal Single-cell Inter- and Intra-cellular Signalling Analysis
Opzoomer, J. W.; O'Sullivan, R.; Sufi, J.; Madsen, R. R.; Qin, X.; Basiarz, E.; Tape, C. J.
10.1101/2024.02.23.581433 — cancer biology — Posted on 2024-03-11
3529 Improving generalizability for MHC-I binding peptide predictions through geometric deep learning
Marzella, D. F.; Crocioni, G.; Radusinovic, T.; Lepikhov, D.; Severin, H.; Bodor, D. L.; Rademaker, D. T.; Lin, C.; Georgievska, S.; Renaud, N.; Kessler, A. L.; Lopez-Tarifa, P.; Buschow, S.; Bekkers, E.; Xue, L. C.
10.1101/2023.12.04.569776 — bioinformatics — Posted on 2024-03-11
3531 Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models
LI, W.; Jiang, X.; Wang, W.; Hou, L.; Cai, R.; Li, Y.; Gu, Q.; Chuai, G.; Chen, Q.; Ma, P.; Tang, J.; Guo, M.; Huang, X.; Zhang, J.; Liu, Q.
10.1101/2024.03.11.583506 — bioinformatics — Posted on 2024-03-11
3532 PseudoCell: A Multi-Valued Logical Regulatory Network to Investigate Premature Senescence Dynamics and Heterogeneity
Pierdona, V.; Lavandoski, P.; Maurmann, R. M.; Borges, G. A.; Mombach, J. C. M.; Guma, F. T. C. R.; Barbe-Tuana, F. M.
10.1101/2023.07.20.549793 — bioinformatics — Posted on 2024-03-11
3533 Structural basis of substrate transport and drug recognition by the human thiamine transporter SLC19A3
Gabriel, F.; Spriestersbach, L.; Fuhrmann, A.; Jungnickel, K. E. J.; Mostafavi, S.; Pardon, E.; Steyaert, J.; Loew, C.
10.1101/2024.03.11.584396 — biochemistry — Posted on 2024-03-11
3540 An EpCAM/Trop2 mechanostat differentially regulates individual and collective behaviour of human carcinoma cells
Aslemarz, A.; Fagotto-Kaufmann, M.; Ruppel, A.; Fagotto-Kaufmann, C.; Balland, M.; Lasko, P.; Fagotto, F.
10.1101/2022.10.03.510449 — cell biology — Posted on 2024-03-11
3542 P66Shc Mediates SUMO2-induced Endothelial Dysfunction
Kumar, J.; Uppulapu, s. K.; Kumari, S.; Sharma, K.; Paradee, W. J.; Yadav, R. P.; Kumar, V.; Kumar, S.
10.1101/2024.01.24.577109 — cell biology — Posted on 2024-03-11
3543 Nucleomorph phylogenomics suggests a deep and ancient origin of cryptophyte plastids within Rhodophyta
Novak, L. V. F.; Munoz-Gomez, S. A.; van Beveren, F.; Ciobanu, M.; Eme, L.; Lopez-Garcia, P.; Moreira, D.
10.1101/2024.03.10.584144 — microbiology — Posted on 2024-03-11
3544 SARS-CoV-2 Omicron BA.2.87.1 Exhibits Higher Susceptibility to Serum Neutralization Than EG.5.1 and JN.1
Wang, Q.; Guo, Y.; Schwanz, L. T.; Mellis, I. A.; Sun, Y.; Qu, Y.; Urtecho, G.; Valdez, R.; Stoneman, E.; Gordon, A.; Wang, H. H.; Liu, L.; Ho, D. D.
10.1101/2024.03.10.584306 — microbiology — Posted on 2024-03-11
3545 Variant mutation in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation
Kubinski, H. C.; Despres, H. W.; Johnson, B. A.; Schmidt, M. M.; Jaffrani, S. A.; Mills, M. G.; Lokugamage, K.; Dumas, C. M.; Shirley, D. J.; Estes, L. K.; Pekosz, A.; Crothers, J. W.; Roychoudhury, P.; Greninger, A. L.; Jerome, K. R.; Martorelli Di Genova, B.; Walker, D. H.; Ballif, B. A.; Ladinsky, M. S.; Bjorkman, P. J.; Menachery, V. D.; Bruce, E. A.
10.1101/2024.03.08.584120 — microbiology — Posted on 2024-03-11
3546 Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis
Secli, V.; Michetti, E.; Pacello, F.; Iacovelli, F.; Falconi, M.; Astolfi, M. L.; Visaggio, D.; Visca, P.; Ammendola, S.; Battistoni, A.
10.1101/2024.01.07.574578 — microbiology — Posted on 2024-03-11
3547 The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017
Catani, J. P.; Smet, A.; Ysenbaert, T.; Vuylsteke, M.; Bottu, G.; Mathys, J.; Botzki, A.; Cortes-Garcia, G.; Strudnell, T.; Gomila, R.; Hamberger, J.; Catalan, J.; Ustyugova, I.; Farrell, T.; Stegalkina, S.; Ray, S.; LaRue, L.; Saelens, X.; Vogel, T. U.
10.1101/2023.08.30.555500 — immunology — Posted on 2024-03-11
3549 Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain
Nguyen, J. H.; Curtis, M. A.; Imami, A. S.; Ryan, W. G.; Alganem, K.; Neifer, K. L.; Saferin, N.; Nawor, C. N.; Kistler, B. P.; Miller, G. W.; Shukla, R.; McCullumsmith, R. E.; Burkett, J. P.
10.1101/2023.08.28.555113 — neuroscience — Posted on 2024-03-11
3551 Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy
Rhymes, E. R.; Simkin, R. L.; Qu, J.; Villarroel-Campos, D.; Surana, S. N.; Tong, Y.; Shapiro, R.; Burgess, R. W.; Yang, X.-L.; Schiavo, G.; Sleigh, J. N.
10.1101/2023.04.09.536152 — neuroscience — Posted on 2024-03-11
3552 The transcriptional response of cortical neurons to concussion reveals divergent fates after injury
Alkaslasi, M. R.; Lloyd, E. Y. H.; Gable, A. S.; Silberberg, H.; Yarur, H. E.; Tsai, V. S.; Tejeda, H. A.; Le Pichon, C. E.
10.1101/2024.02.26.581939 — neuroscience — Posted on 2024-03-11
3553 Spatial, transcriptomic and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition
Arokiaraj, C.; Leone, M.; Kleyman, M.; Chamessian, A.; Phan, B. N.; Lopes, B. C.; Cherupally, V. K.; Noh, M.-C.; Corrigan, K. A.; Yeramosu, D.; Franusich, M. E.; Podder, R.; Leie, S.; Shiers, S.; Kang, B.; Kennedy, M.; Dum, R.; Lewis, D.; Qadri, Y.; Price, T.; Pfenning, A.; Seal, R.
10.1101/2022.04.01.486135 — neuroscience — Posted on 2024-03-11
3556 Light-driven synchronization of optogenetic clocks
Cannarsa, M. C.; Liguori, F.; Pellicciotta, N.; Frangipane, G.; Di Leonardo, R.
10.1101/2023.10.24.563722 — synthetic biology — Posted on 2024-03-11
3558 PEGylated recombinant Aplysia punctata ink toxin depletes arginine and lysine and inhibits growth of tumor xenografts
Wolkersdorfer, A.; Bergmann, B.; Adelmann, J.; Ebbinghaus, M.; Guenther, E.; Gutmann, M.; Hahn, L.; Hurwitz, R.; Kraehmer, R.; Leenders, F.; Luehmann, T.; Schueler, J.; Schmidt, L.; Teifel, M.; Meinel, L.; Rudel, T.
10.1101/2023.01.17.524398 — cancer biology — Posted on 2024-03-11
3560 Depth-dependent scaling of axial distances in light microscopy
Loginov, S.; Boltje, D.; Hensgens, M. N. F.; Hoogenboom, J. P.; van der Wee, E.
10.1101/2024.01.31.578242 — biophysics — Posted on 2024-03-11
3561 Integrated Proteomics analysis of baseline protein expression in pig tissues
Wang, S.; Collins, A.; Prakash, A.; Fexova, S.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2023.11.07.566009 — bioinformatics — Posted on 2024-03-11
3564 SIDERITE: Unveiling Hidden Siderophore Diversity in the Chemical Space Through Digital Exploration
He, R.; Gu, S.; Xu, J.; Li, X.; Chen, H.; Shao, Z.; Wang, H.; Shao, J.; Yin, W.-B.; Qian, L.; Wei, Z.; Li, Z.
10.1101/2023.08.31.555687 — biochemistry — Posted on 2024-03-11
3566 Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness
Amelink, J. S.; Postema, M. C.; Kong, X.-Z.; Schijven, D.; Carrion-Castillo, A.; Soheili-Nezhad, S.; Sha, Z.; Molz, B.; Joliot, M.; Fisher, S. E.; Francks, C.
10.1101/2023.11.22.568256 — genomics — Posted on 2024-03-11
3570 Age-related dysregulation of the retinal transcriptome in African turquoise killifish
Bergmans, S.; Noel, N. C.; Masin, L.; Harding, E. G.; Krzywanska, A. M.; De Schutter, J. D.; Ayana, R.; Hu, C.-K.; Arckens, L.; Ruzycki, P. A.; Clark, B. S.; MacDonald, R. B.; Moons, L.
10.1101/2024.02.21.581372 — neuroscience — Posted on 2024-03-11
3572 Pharmacological inhibition of macrophage triglyceride biosynthesis pathways does not improve Mycobacterium tuberculosis control in infected mice
Castillo, J. R.; Guerrini, V.; Quijada, D.; Karanika, S.; Neupane, P.; Harris, H.; Garcia, A.; Shenkoya, B.; Yilma, A.; Bailey, H.; Khan, R.; Gopalakrishnan, M.; Gennaro, M. L.; Karakousis, P. C.
10.1101/2024.03.06.583745 — pharmacology and toxicology — Posted on 2024-03-11
3575 Lit-OTAR Framework for Extracting Biological Evidences from Literature
Tirunagari, S.; Saha, S.; Venkatesan, A.; Suveges, D.; Buniello, A.; Ochoa, D.; McEntyre, J.; McDonagh, E.; Harrison, M.
10.1101/2024.03.06.583722 — bioinformatics — Posted on 2024-03-11
3577 Mechanisms underlying the loss of migratory behaviour in a long-lived bird
Andrade, P.; Franco, A. M. A.; Acacio, M.; Afonso, S.; Marques, C. I.; Moreira, F.; Carneiro, M.; Catry, I.
10.1101/2024.03.06.583673 — evolutionary biology — Posted on 2024-03-11
3578 Adaptive trade-offs between vertebrate defense and insect predation drive ant venom evolution
Touchard, A.; Robinson, S. D.; Lalague, H.; Ascoet, S.; Billet, A.; Dejean, A.; Tene, N. J.; Petitclerc, F.; Troispoux, V.; Treilhou, M.; Bonnafe, E.; Vetter, I.; Vizueta, J.; Moreau, C. S.; Orivel, J.; Tysklind, N.
10.1101/2024.03.06.583705 — ecology — Posted on 2024-03-11
3579 Ectomycorrhizal fungi are influenced by ecoregion boundaries across Europe
Delhaye, G.; van der Linde, S.; Bauman, D.; Orme, D. C. L.; Suz, L. M.; Bidartondo, M. I.
10.1101/2024.03.06.583687 — ecology — Posted on 2024-03-11
3580 Buzz-world: Global patterns and drivers of buzzing bees and poricidal plants
Russell, A. L.; Buchmann, S. L.; Ascher, J. S.; Wang, Z.; Kriebel, R.; Jolles, D. D.; Orr, M. C.; Hughes, A. C.
10.1101/2024.03.06.583730 — ecology — Posted on 2024-03-11
3582 Dynamic properties in functional connectivity changes and striatal dopamine deficiency in Parkinson's disease
Asendorf, A. L.; Theis, H.; Tittgemeyer, M.; Timmermann, L.; Fink, G. R.; Drzezga, A.; Eggers, C.; Hoenig, M. C.; van Eimeren, T.
10.1101/2024.03.06.583342 — neuroscience — Posted on 2024-03-11
3585 PVN-mPFC OT projections modulates pup-directed pup care or attacking in virgin mandarin voles
Li, L.; He, Z.; Li, Y.; Huang, C.; Hou, W.; Lv, Z.; Zhang, L.; Qu, Y.; Sun, Y.; Huang, K.; Han, X.; Tai, F.-D.
10.1101/2024.03.06.583718 — neuroscience — Posted on 2024-03-11
3586 Maternal Alcohol Drinking Patterns Predict Offspring Neurobehavioral Outcomes
Myrick, A. R.; Jimenez, D.; Jacquez, B.; Noor, S.; Sun, M. S.; Milligan, E. D.; Valenzuela, C. F.; Linsenbardt, D.
10.1101/2024.03.06.583121 — neuroscience — Posted on 2024-03-11
3587 A Novel, Robust, and Portable Platform for Magnetoencephalography using Optically Pumped Magnetometers
Schofield, H.; Hill, R. M.; Feys, O. M.; Holmes, N.; Osborne, J.; Doyle, C.; Bobela, D.; Corvilain, P.; Wens, V.; Rier, L.; Bowtell, R.; Ferez, M.; Mullinger, K. J.; Coleman, S.; Rhodes, N.; Rea, M.; Tanner, Z.; Boto, E.; De Tiege, X.; Shah, V.; Brookes, M. J.
10.1101/2024.03.06.583313 — neuroscience — Posted on 2024-03-11
3589 FGF21 deletion mildly exacerbates hepatic dysfunction in MASH diet and alcohol fed rats
Aldiss, P.; Nielsen, M. H.; Burm, H.; Oro, D.; Hansen, H. H.; Feigh, M.; Gillum, M. P.
10.1101/2024.03.06.583704 — physiology — Posted on 2024-03-11
3590 Air-liquid interface exposure of A549 human lung cells to characterize the hazard potential of a gaseous bio-hybrid fuel blend
Daniel, J.; Schönberger Alvarez, A. A.; te Heesen, P.; Lehrheuer, B.; Pischinger, S.; Hollert, H.; Ross-Nickoll, M.; Du, M.
10.1101/2024.03.06.583741 — pharmacology and toxicology — Posted on 2024-03-11
3593 HSV-1 infection induces a downstream-shift of +1 nucleosomes
Weiss, E.; Whisnant, A. W.; Hennig, T.; Djakovic, L.; Doelken, L.; Friedel, C. C.
10.1101/2024.03.06.583707 — bioinformatics — Posted on 2024-03-11
3594 Prediction of Aggregation Prone Regions in Proteins Using Deep Neural Networks and Their Suppression by Computational Design
Cima, V.; Kunka, A.; Grakova, E.; Planas-Iglesias, J.; Havlasek, M.; Subramanian, M.; Beloch, M.; Marek, M.; Slaninova, K.; Damborsky, J.; Prokop, Z.; Bednar, D.; Martinovic, J.
10.1101/2024.03.06.583680 — bioinformatics — Posted on 2024-03-11
3596 MotifScope: a multi-sample motif discovery and visualization tool for tandem repeats
Zhang, Y.; Hulsman, M.; Salazar, A.; Tesi, N.; Knoop, L.; van der Lee, S.; Wijesekera, S.; Krizova, J.; Kamsteeg, E.-J.; Holstege, H.
10.1101/2024.03.06.583591 — genomics — Posted on 2024-03-11
3597 The effect of altitude on the expression of immune-related genes in Peruvian rural indigenous
Jaramillo-Valverde, L.; de Araujo, G. S.; Poterico, J. A.; Martinez-Jaramillo, C.; Roa-Linares, V.; Alvites-Arrieta, S.; Pablo-Ramirez, N.; Ubillus, M.; Palma-Lozano, D.; Silva-Carvalho, C.; Vasconcelos-da-Gama, L.; Costa, L. F.; Tarazona-Santos, E.; Raychaudhuri, S.; Guio, H.
10.1101/2024.03.06.583674 — genetics — Posted on 2024-03-11
3599 A Drosophila model to screen Alport syndrome COL4A5 variants for their functional pathogenicity
Duan, J.; Wen, P.; Zhao, Y.; van de Leemput, J.; Lai, J.; Fermin, D.; Warady, B. A.; Furth, S. L.; Ng, D. K.; Sampson, M.; Han, Z.
10.1101/2024.03.06.583697 — genetics — Posted on 2024-03-11
3609 T cell cholesterol transport is a metabolic checkpoint that links intestinal immune responses to dietary lipid absorption
Gao, Y.; Kennelly, J. P.; Xiao, X.; Whang, E.; Ferrari, A.; Bedard, A. H.; Mack, J. J.; Nguyen, A. H.; Weston, T.; Uchiyama, L. F.; Lee, M. S.; Young, S.; Bensinger, S. J.; Tontonoz, P.
10.1101/2024.03.08.584164 — physiology — Posted on 2024-03-11
3613 Optimal placement of high-channel visual prostheses in human retinotopic visual cortex
van Hoof, R.; Lozano, A.; Wang, F.; Klink, P. C.; Roelfsema, P. R.; Goebel, R.
10.1101/2024.03.05.583489 — neuroscience — Posted on 2024-03-11
3618 The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus
Bao, H.; yanan, w.; Li, H.; Wang, Q.; Lei, Y.; Ye, Y.; Zhu, H.; Stacey, G.; Xu, S.; Cao, Y.
10.1101/2024.03.06.583716 — plant biology — Posted on 2024-03-11
3620 A new group of LysM-RLKs involved in symbiotic signal perception and arbuscular mycorrhiza establishment
Ding, Y.; Gasciolli, V.; Medioni, L.; Gaston, M.; de-Regibus, A.; Rembliere, C.; Bono, J.-J.; Cullimore, J.; Dalmais, M.; Saffray, C.; Mazeau, S.; Bendahmane, A.; Sibout, R.; Vandenbussche, M.; Rouster, J.; Wang, T.; He, G.; Masselin, A.; Cottaz, S.; Fort, S.; Lefebvre, B.
10.1101/2024.03.06.583654 — plant biology — Posted on 2024-03-11
3625 MYB68 orchestrates cork differentiation by regulating stem cell proliferation and suberin deposition
Molina, D.; Horvath, S.; Zhang, X.; Xiao, W.; Ragab, N.; Ripper, D.; Kilian, J.; Andersen, T. G.; Ragni, L.
10.1101/2024.03.06.583666 — plant biology — Posted on 2024-03-11
3627 OligoY pipeline for full Y chromosome painting
Almeida, I.; Bonilla Bruno, H.; Lisboa Santana Pinheiro, M. M.; Bernardo de Carvalho, A.; Vibranovski, M. D.
10.1101/2024.03.06.583648 — bioinformatics — Posted on 2024-03-11
3637 Parsimonious EBM: generalising the event-based model of disease progression for simultaneous events
Parker, C. S.; Oxtoby, N. P.; Young, A. L.; Alzheimer's Disease Neuroimaging Initiative, ; Alexander, D. C.; Zhang, H.
10.1101/2022.07.10.499471 — neuroscience — Posted on 2024-03-11
3638 Neuronal substance-P drives breast cancer growth and metastasis via an extracellular RNA/TLR7 axis
Padmanaban, V.; Keller, I.; Seltzer, E. S.; Ostendorf, B. N.; Kerner, Z.; Tavazoie, S. F.
10.1101/2024.03.08.584128 — cancer biology — Posted on 2024-03-11
3640 Making Moral Decisions With Artificial Agents As Advisors. An fNIRS Study
Fabre, E. F.; Mouratille, D.; Bonnemain, V.; Palmiotti, G.-P.; Causse, M.
10.1101/2024.03.05.583335 — neuroscience — Posted on 2024-03-11
3641 Dopamine dynamics in chronic pain: music-induced sex-dependent behavioral effects in mice
Flores-Garcia, M.; Flores de los Heros, A.; Aso, E.; Grau-Sanchez, J.; Videla, S.; Rodriguez-Fornells, A.; Bonaventura, J.; Fernandez-Duenas, V.
10.1101/2024.03.05.583510 — neuroscience — Posted on 2024-03-11
3642 Structure-based discovery of CFTR potentiators and inhibitors
Liu, F.; Kaplan, A. L.; Levring, J.; Einsiedel, J.; Tiedt, S.; Distler, K.; Omattage, N.; Kondratov, I. S.; Moroz, Y. S.; Pietz, H. L.; Irwin, J. J.; Gmeiner, P.; Shoichet, B. K.; Chen, J.
10.1101/2023.09.09.557002 — biophysics — Posted on 2024-03-11
3643 hAMRonization: Enhancing antimicrobial resistance prediction using the PHA4GE AMR detection specification and tooling
Mendes, I.; Griffiths, E.; Manuele, A.; Fornika, D.; Tausch, S. H.; Le Viet, T.; Phelan, J.; Meehan, C. J.; Raphenya, A. R.; Alcock, B.; Culp, E. J.; Lorenzo, F.; Haim, M. S.; Witney, A.; Black, A.; Katz, L.; Oluniyi, P.; Olawoye, I.; Timme, R. E.; Neoh, H.-m.; Lam, S. D.; Jamaluddin, T. Z. M. T.; Nathan, S.; Ang, M. Y.; Di Gregorio, S.; Vandelannoote, K.; Dusadeepong, R.; Chindelevitch, L.; Nasar, M. I.; Aanensen, D.; Afolayan, A. O.; Odih, E. E.; McArthur, A. G.; Feldgarden, M.; Galas, M. M.; Campos, J.; Okeke, I. N.; Underwood, A.; Page, A. J.; MacCannell, D.; Maguire, F.
10.1101/2024.03.07.583950 — bioinformatics — Posted on 2024-03-11
3647 Cross-continental variation of herbivore resistance in a global plant invader
Cao, P.; Liao, Z.; Zhang, L.; Wang, S.; Bi, J.; Zhao, Y.; Parepa, M.; Lin, T.; Guo, Y.; Bossdorf, O.; Richards, C. L.; Endriss, S. B.; Wu, J.; Ju, R.; Li, B.
10.1101/2023.12.13.571471 — ecology — Posted on 2024-03-11
3648 Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex
Guo, Q.; Chen, K.-E.; Gimenez-Andres, M.; Jellett, A.; Gao, Y.; Simonetti, B.; Liu, M.; Danson, C.; Heesom, K. J.; Cullen, P. J.; Collins, B. M.
10.1101/2023.08.15.553351 — cell biology — Posted on 2024-03-11
3650 Spatial patterns of Hyalomma marginatum-borne pathogens in the Occitanie region (France), a focus on the intriguing dynamics of Rickettsia aeschlimannii
KUKLA, C. J.; Bernard, C.; Bru, D.; Galon, C.; Giupponi, C.; Huber, K.; Jourdan-Pineau, H.; Malandrin, L.; Rakotoarivony, I.; Riggi, C.; Vial, L.; Moutailler, S.; Pollet, T.
10.1101/2024.03.05.583534 — microbiology — Posted on 2024-03-11
3652 Modelling Glioma Stem Cell-mediated Tumorigenesis Using Zebrafish PDX Systems
Mahendran, H. P.; Cieslukowski, A.; Lubanska, D.; Philbin, N.; Stringer, K. F.; Habashy, P.; Stover, M.; deCarvalho, A.; Soliman, M.; Shamisa, A.; Porter, L.
10.1101/2024.02.27.580776 — cancer biology — Posted on 2024-03-11
3656 Methodological choices matter: A systematic comparison of TMS-EEG studies targeting the primary motor cortex
Beck, M. M.; Heyl, M.; Mejer, L.; Vinding, M. C.; Christiansen, L.; Tomasevic, L.; Siebner, H. R.
10.1101/2024.03.08.583873 — neuroscience — Posted on 2024-03-11
3660 Normative models combining fetal and postnatal MRI data to characterize neurodevelopmental trajectories during the transition from in- to ex-utero
Mihailov, A.; Pron, A.; Lefevre, J.; Deruelle, C.; Desnous, B.; Bretelle, F.; Manchon, A.; Milh, M.; Rousseau, F.; Auzias, G.; Girard, N.
10.1101/2024.03.07.583908 — neuroscience — Posted on 2024-03-11
3661 Persistent cognitive deficits in anti-LGI1 encephalitis are linked to a reorganization of structural brain networks
Krohn, S.; Mueller-Jensen, L.; Kuchling, J.; Romanello, A.; Bartsch, T.; Leypoldt, F.; Paul, F.; Pruess, H.; Finke, C.
10.1101/2024.03.07.583948 — neuroscience — Posted on 2024-03-11
3663 Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editing
Lodewijk, G. A.; Kozuki, S.; Han, C.; Topacio, B. R.; Zargari, A.; Lee, S.; Knight, G.; Ashton, R.; Qi, L. S.; Shariati, S. A.
10.1101/2024.03.05.583597 — developmental biology — Posted on 2024-03-11
3666 Nucleomorph phylogenomics suggests a deep and ancient origin of cryptophyte plastids within Rhodophyta
Novak, L. V. F.; Munoz-Gomez, S. A.; van Beveren, F.; Ciobanu, M.; Eme, L.; Lppez-Garcia, P.; Moreira, D.
10.1101/2024.03.10.584144 — microbiology — Posted on 2024-03-11
3668 Single molecule fingerprinting reveals different growth mechanisms in seed amplification assays for different polymorphs of alpha Synuclein fibrils.
Lau, D.; Tang, Y.; Kenche, V.; Copie, T.; Kempe, D.; Jary, E.; Graves, N. J.; Biro, M.; Masters, C. L.; Dzamko, N.; Gambin, Y.; Sierecki, E.
10.1101/2024.03.05.583619 — neuroscience — Posted on 2024-03-11
3669 TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease models
Andreasson, K. I.; Wilson, E. N.; Wang, C.; Xin, M.; Panchal, M.; Rabinowitz, J. D.; Minhas, P. S.; Swarovski, M. S.; Benitez, J. A. R.; Durairaj, A. S.; Chaney, A.; Iweka, C. A.; Buckwalter, M. S.; Ennerfelt, H. E.; Umans, J.; Huang, J.; Zera, K. A.; McReynolds, M. R.; Greicius, M. D.; James, M. L.; Mehta, S. S.; Le Guen, Y.; Tan, Y. J.; Zuckerman, A. J.; Blacher, E.; Gauba, E.; Serrano, G. E.; Cropper, H.; Jain, P.; Liu, Q.
10.1101/2024.03.05.583562 — neuroscience — Posted on 2024-03-11
3671 Reconfigurable multi-component nanostructures built from DNA origami voxels
Luu, M. T.; Berengut, J.; Daljit Singh, J. K.; Coffi Dit Glieze, K.; Turner, M.; Skipper, K.; Meppat, S.; Abbas, A.; Fowler, H.; Close, W.; Doye, J. P. K.; Wickham, S. F. J.
10.1101/2024.03.10.584331 — synthetic biology — Posted on 2024-03-11
3672 Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK
Bowman, C. E.; Neinast, M. D.; Jang, C.; Patel, J.; Blair, M. C.; Mirek, E. T.; Jonsson, W. O.; Chu, Q.; Merlo, L.; Mandik-Nayak, L.; Anthony, T. G.; Rabinowitz, J. D.; Arany, Z.
10.1101/2024.03.05.582974 — pharmacology and toxicology — Posted on 2024-03-11
3673 Applicability of AlphaFold2 in the modelling of coiled-coil domains
Madaj, R.; Martinez-Goikoetxea, M.; Kaminski, K.; Ludwiczak, J.; Dunin-Horkawicz, S.
10.1101/2024.03.07.583852 — bioinformatics — Posted on 2024-03-10
3674 Molecular Genomic Insights into Melanoma Associated Proteins PRAME and BAP1
Nawn, D.; Hassan, S. S.; Hromic Jahjefendic, A.; Bhattacharya, T.; Basu, P.; Redwan, E. M.; Barh, D.; Andrade, B.; Aljabali, A. A.; Serrano Aroca, A.; Lundstrom, K.; Tambuwala, M. M.; Uversky, V. N.
10.1101/2024.03.05.583532 — bioinformatics — Posted on 2024-03-11
3675 Uncalled4 improves nanopore DNA and RNA modification detection via fast and accurate signal alignment
Kovaka, S.; Hook, P. W.; Jenike, K. M.; Shivakumar, V.; Morina, L. B.; Razaghi, R.; Timp, W.; Schatz, M. C.
10.1101/2024.03.05.583511 — bioinformatics — Posted on 2024-03-11
3676 Analysis and visualization of quantitative proteomics data using FragPipe-Analyst
Hsiao, Y.; Zhang, H.; Li, G. X.; Deng, Y.; Yu, F.; Kahrood, H. V.; Steele, J. R.; Schittenhelm, R. B.; Nesvizhskii, A. I.
10.1101/2024.03.05.583643 — bioinformatics — Posted on 2024-03-11
3678 zIncubascope: long-term quantitative imaging of multi-cellular assemblies inside an incubator
Jana, A.; Mekhileri, N.; Boyreau, A.; Bazin, A.; Pujol, N.; Alessandri, K.; Recher, G.; Nassoy, P.; Badon, A.
10.1101/2024.03.05.583476 — bioengineering — Posted on 2024-03-10
3681 Structure-based probe reveals the presence of large transthyretin aggregates in plasma of ATTR amyloidosis patients
Pedretti, R.; Wang, L.; Yakubovska, A.; Zhang, Q. S.; Nguyen, B.; Grodin, J. L.; Masri, A.; Saelices, L.
10.1101/2024.03.09.584228 — molecular biology — Posted on 2024-03-10
3683 Dietary restriction reveals sex-specific expression of the mTOR pathway genes in Japanese quails
Reda, G. K.; Ndunguru, S. F.; Csernus, B.; Knop, R.; Lugata, J. K.; Szabo, C.; Czegledi, L.; Lendvai, A. Z.
10.1101/2024.03.10.584307 — molecular biology — Posted on 2024-03-11
3685 Pf bacteriophages hinder sputum antibiotic diffusion via electrostatic binding
Chen, Q.; Cai, P.; Chang, T. H. W.; Burgener, E.; Kratochvil, M. J.; Gupta, A.; Hargil, A.; Secor, P. R.; Nielsen, J. E.; Barron, A. E.; Milla, C.; Heilshorn, S. C.; Spakowitz, A. J.; Bollyky, P. L.
10.1101/2024.03.10.584330 — microbiology — Posted on 2024-03-10
3686 Cas1 mediates the interference stage in a phage-encoded CRISPR-Cas system
Zhang, L.; Wang, H.; Zeng, J.; Cao, X.; Gao, Z.; Liu, Z.; Li, F.; Wang, J.; Zhang, Y.; Yang, M.; Feng, Y.
10.1101/2024.03.09.584257 — microbiology — Posted on 2024-03-11
3687 Myc Dysregulation in Activated Macrophages Initiates Iron-Mediated Lipid Peroxidation that Fuels Type I Interferon and Compromises TB Resistance
Yabaji, S. M.; Zhernovkov, V.; Araveti, P. B.; Lata, S.; Rukhlenko, O. S.; Abdullatif, S. A.; Alekseev, Y.; Ma, Q.; Dayama, G.; Lau, N. C.; Bishai, W. R.; Crossland, N. A.; Campbell, J. D.; Kholodenko, B. N.; Gimelbrant, A. A.; Kobzik, L.; Kramnik, I.
10.1101/2024.03.05.583602 — immunology — Posted on 2024-03-10
3695 de novo diploid genome assembly using long noisy reads
Nie, F.; Ni, P.; Huang, N.; Zhang, J.; Wang, Z.; Xiao, C.-L.; Luo, F.; Wang, J.
10.1101/2022.09.25.509436 — bioinformatics — Posted on 2024-03-10
3696 On the identification of differentially-active transcription factors from ATAC-seq data
Gerbaldo, F.; Sonder, E.; Fischer, V.; Frei, S.; Wang, J.; Gapp, K.; Robinson, M. D.; Germain, P.-L.
10.1101/2024.03.06.583825 — bioinformatics — Posted on 2024-03-10
3703 Saltational episodes of reticulate evolution in the Drosophila saltans species group
Prediger, C.; Ferreira, E. A.; Zorzato, S. V.; Hua-Van, A.; Klasson, L.; Miller, W.; Yassin, A.; Madi-Ravazzi, L.
10.1101/2023.10.09.561511 — evolutionary biology — Posted on 2024-03-10
3705 Nitrogen niche partitioning between tropical legumes and grasses conditionally weakens under elevated CO2
Churchill, A. C.; Zhang, H.; Kim, G. w.; Catunda, K. L. M.; Anderson, I. C.; Isbell, F. I.; Moore, B.; Pendall, E.; Plett, J. M.; Powell, J.; Power, S. A.
10.1101/2023.01.16.524162 — ecology — Posted on 2024-03-10
3706 Cross-continental variation of herbivore resistance in a global plant invader
Cao, P.; Liao, Z.; Wang, S.; Zhang, L.; Lin, T.; Parepa, M.; Bi, J.; Zhao, Y.; Guo, Y.; Bossdorf, O.; Richards, C. L.; Endriss, S. B.; Wu, J.; Ju, R.; Li, B.
10.1101/2023.12.13.571471 — ecology — Posted on 2024-03-10
3707 A host AAA-ATPase exhibits bacteriolytic activity for clearance of microbial infection
Ghosh, S.; Roy, S.; Baid, N.; Das, U. K.; Rakshit, S.; Sanghavi, P.; Hajra, D.; Menon, S.; Sahil, M.; Shaw, S.; Rajmani, R. S.; Adicherla, H.; Mondal, J.; Chakravortty, D.; Mallik, R.; Banerjee, A.
10.1101/2023.07.18.549519 — cell biology — Posted on 2024-03-10
3708 DERIVATION OF ELEPHANT INDUCED PLURIPOTENT STEM CELLS
Appleton, E. M.; Hong, K.; Rodriguez-Caycedo, C.; Tanaka, Y.; Ashkenazy-Titelman, A.; Bhide, K.; Rasmussen-Ivey, C.; Ambriz-Pena, X.; Korover, N.; Bai, H.; Quieroz, A.; Nelson, J.; Rathod, G.; Knox, G.; Morgan, M.; Malviya, N.; Zhang, K.; Kehler, J.; Kowalczyk, A.; Bow, A.; McLendon, B.; Cantarel, B. L.; James, M.; Mason, C. E.; Gray, C.; Koehler, K.; Pearson, V.; Lamm, B.; Church, G.; Hysolli, E.
10.1101/2024.03.05.583606 — cell biology — Posted on 2024-03-10
3713 SAMson: an automated brain extraction tool for rodents using SAM
Soler, D. P.; Selim, M. K.; Munoz-Moreno, E.; Ramos-Cabrer, P.; Lopez-Larrubia, P.; Pertusa, A.; De Santis, S.; Canals, S.
10.1101/2024.03.07.583982 — neuroscience — Posted on 2024-03-10
3719 Next-generation sequencing analysis with a population-specific reference genome
Suzuki, T.; Ninomiya, K.; Funayama, T.; Okamura, Y.; Tadaka, S.; the Tohoku Medical Megabank Project Study Group, ; Kinoshita, K.; Yamamoto, M.; Kure, S.; Kikuchi, A.; Tamiya, G.; Takayama, J.
10.1101/2024.03.07.584017 — bioinformatics — Posted on 2024-03-10
3721 DeST-OT: Alignment of Spatiotemporal Transcriptomics Data
Halmos, P.; Liu, X.; Gold, J.; Chen, F.; Ding, L.; Raphael, B.
10.1101/2024.03.05.583575 — bioinformatics — Posted on 2024-03-10
3722 How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies
Bouras, G.; Judd, L. M.; Edwards, R. A.; Vreugde, S.; Stinear, T. P.; Wick, R. R.
10.1101/2024.03.07.584013 — bioinformatics — Posted on 2024-03-10
3723 Variation and interaction of distinct subgenomes contribute to growth diversity in intergeneric hybrid fish
Ren, L.; Luo, M.; Cui, J.; Gao, X.; Zhang, H.; Wu, P.; Wei, Z.; Tai, Y.; Li, M.; Luo, K.; Liu, S.
10.1101/2024.03.07.584006 — genetics — Posted on 2024-03-10
3724 Strain heterogeneity in a non-pathogenic fungus highlights factors contributing to virulence
Rinker, D. C.; Sauters, T. J. C.; Steffen, K.; Gumilang, A.; Raja, H. A.; Rangel-Grimaldo, M.; Pinzan, C. F.; de Castro, P. A.; dos Reis, T. F.; Delbaje, E.; Houbraken, J.; Goldman, G. H.; Oberlies, N. H.; Rokas, A.
10.1101/2024.03.08.583994 — evolutionary biology — Posted on 2024-03-10
3726 Sex-specific sub-lethal effects of low virulence entomopathogenic fungi may boost the Sterile Insect Technique
duneau, d.; Gallet, R.; Adhiambo, M.; Deletre, E.; Chailleux, A.; Khamis, F.; Subramanian, S.; Brevault, T.; Fellous, S.
10.1101/2024.03.07.583916 — ecology — Posted on 2024-03-10
3731 A reference database of reptile images
Uetz, P. H.; Patel, M.; Gbadamosi, Z.; Shoope, S.; Nguyen, J.
10.1101/2024.03.08.584020 — zoology — Posted on 2024-03-10
3732 Active fluctuations of cells reduce friction to enable fast and coherent collective migration
Jipp, M.; Wagner, B. D.; Egbringhoff, L.; Teichmann, A.; Ruebeling, A.; Nieschwitz, P.; Honigmann, A.; Chizhik, A.; Oswald, T. A.; Janshoff, A.
10.1101/2024.03.07.583903 — biophysics — Posted on 2024-03-10
3734 Acute, chronic and conditioned effects of intranasal oxytocin in the mu opioid receptor knockout mouse model of autism: social context matters
Pantouli, F.; Pujol, C.; Derieux, C.; Fonteneau, M.; Pellissier, L.; Marsol, C.; Karpenko, J.; Bonnet, D.; Hibert, M.; Bailey, A.; Le Merrer, J.; BECKER, J. A. J.
10.1101/2024.03.07.583912 — animal behavior and cognition — Posted on 2024-03-10
3735 Breaking the rule: An exceptional Y chromosome introgression between deeply divergent primate species
Jensen, A.; Horton, E. R.; Amboko, J.; Parke, S.-A.; Hart, J. A.; Tosi, A.; Guschanski, K.; Detwiler, K. M.
10.1101/2024.03.07.583898 — evolutionary biology — Posted on 2024-03-10
3737 CMTM6 maintains B cell intrinsic CD40 expression to regulate anti-tumor immunity
Long, Y.; Chen, R.; Chang, W.; Luo, H.; Li, F.; Sun, J.; Chen, J.; Gong, L.
10.1101/2024.03.05.583639 — immunology — Posted on 2024-03-10
3739 Transcriptional dynamics of the murine heart during perinatal development at single-cell resolution
Feulner, L.; Wuennemann, F.; Liang, J.; Hofmann, P.; Hitz, M.-P.; Schapiro, D.; Leclerc, S.; van Vliet, P. P.; Andelfinger, G.
10.1101/2024.03.05.583423 — developmental biology — Posted on 2024-03-10
3742 Survivin in synergy with BAF/SWI complex binds bivalent chromatin regions and activates DNA damage response in CD4+ T cells
Chandrasekaran, V.; Andersson, K. M. E.; Erlandsson, M. C.; Li, S.; Garcia-Bonete, M.-J.; Malmhall-Bah, E.; Johansson, P.; Katona, G.; Bokarewa, M. I.
10.1101/2024.03.05.583464 — immunology — Posted on 2024-03-10
3745 Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies
Sridhar, S.; Vystrcilova, M.; Khani, M. H.; Karamanlis, D.; Schreyer, H. M.; Ramakrishna, V.; Krueppel, S.; Zapp, S. J.; Mietsch, M.; Ecker, A.; Gollisch, T.
10.1101/2024.03.05.583449 — neuroscience — Posted on 2024-03-10
3746 Microglia Depletion leads to Increased Susceptibility to Ocular Hypertension-Dependent Glaucoma
Diemler, C. A.; MacLean, M.; Heuer, S. E.; Wain, A.; Marola, O. J.; LIbby, R. T.; Howell, G.
10.1101/2024.03.05.583529 — neuroscience — Posted on 2024-03-10
3748 Generative interpolation and restoration of images using deep learning for improved 3D tissue mapping
Joshi, S.; Forjaz, A.; Sang Han, K.; Shen, Y.; Xenes, D.; Matelsky, J.; Wester, B.; Munoz-Barrutia, A.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.
10.1101/2024.03.07.583909 — bioinformatics — Posted on 2024-03-10
3752 Strategies for Inducing and Validating Zinc Deficiency and Zinc Repletion
Wenegieme, T.-Y.; Elased, D.; Rockwood, J.; Hasrat, K.; McMichael, K.; Marshall, A.; Neikirk, K.; Kirabo, A.; Elased, K.; Hinton, A.; Williams, C.
10.1101/2024.02.28.582542 — physiology — Posted on 2024-03-10
3754 General Capillary Endothelial Cells Undergo Reprogramming into Arterial Endothelial Cells in Pulmonary Hypertension through HIF-2α/Notch4 Pathway
Liu, B.; Yi, D.; Xia, X.; Ramirez, K.; Zhao, H.; Cao, Y.; Tripathi, A.; Dong, R.; Gao, A.; Ding, H.; Qiu, S.; Kalinichenko, V. V.; Fallon, M. B.; Dai, Z.
10.1101/2024.02.13.580227 — physiology — Posted on 2024-03-10
3755 Encompassing view of spatial and single-cell RNA-seq renews the role of the microvasculature in human atherosclerosis
Bleckwehl, T.; Maryam, S.; Babler, A.; Bosteen, M.; Nyberg, M.; Halder, M.; Hvid, H.; Pyke, C.; Voetmann, L. M.; Sluimer, J.; Das, V.; Baumgart, S.; Kramann, R.; Hayat, S.
10.1101/2023.12.15.571796 — bioinformatics — Posted on 2024-03-10
3756 Impaired central pattern generators due to abnormal EPHA4 signaling leads to idiopathic scoliosis
Wang, L.; Zhao, S.; Yang, X.; Zheng, P.; Wen, W.; Xu, K.; Cheng, X.; Li, Q.; Khanshour, A. M.; Koike, Y.; Liu, J.; Fan, X.; Otomo, N.; Chen, Z.; Li, Y.; Li, L.; Xie, H.; Zhu, P.; Li, X.; Niu, Y.; Wang, S.; Liu, S.; Yuan, S.; Terao, C.; Li, Z.; Chen, S.; Zhao, X.; Liu, P.; Posey, J. E.; Wu, Z.; Qiu, G.; Ikegawa, S.; Lupski, J.; Rios, J. J.; Wise, C. A.; Zhang, J.; Zhao, C.; Wu, N.
10.1101/2024.03.04.583361 — genetics — Posted on 2024-03-10
3757 A matter of salt: global assessment of the effect of salt ionic composition as a driver of aquatic bacterial diversity
Szabo, A.; Szekely, A. J.; Boros, E.; Marton, Z.; Csitari, B.; Barteneva, N. S.; Anda, D.; Dobosy, P.; Eiler, A.; Bertilsson, S.; Felfoldi, T.
10.1101/2024.03.09.584225 — microbiology — Posted on 2024-03-10
3758 Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer
De Felice, D.; Alaimo, A.; Bressan, D.; Genovesi, S.; Marmocchi, E.; Annesi, N.; Beccaceci, G.; Dalfovo, D.; Cutrupi, F.; Foletto, V.; Lorenzoni, M.; Gandolfi, F.; Kannan, S.; Verma, C. S.; Vasciaveo, A.; Shen, M. M.; Romanel, A.; Chiacchiera, F.; Cambuli, F.; Lunardi, A.
10.1101/2024.03.06.583256 — cancer biology — Posted on 2024-03-10
3759 Epithelial heme oxygenase-1 enhances colonic tumorigenesis by inhibiting ferroptosis
Callahan, R. C.; Bhagavatula, G.; Curry, J.; Staley, A. W.; Schaefer, R. E. M.; Minhajuddin, F.; Zhou, L.; Neuhart, R.; Atif, S. M.; Orlicky, D. J.; Cartwright, I. M.; Gerich, M.; Theiss, A. L.; Hall, C. H.; Colgan, S. P.; Onyiah, J. C.
10.1101/2024.03.06.583112 — cancer biology — Posted on 2024-03-10
3764 On the identification of differentially-active transcription factors from ATAC-seq data
Gerbaldo, F.; Sonder, E.; Fischer, V.; Frei, S.; Wang, J.; Gapp, K.; Robinson, M. D.; Germain, P.-L.
10.1101/2024.03.06.583825 — bioinformatics — Posted on 2024-03-09
3769 Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with reduced kidney function.
Johnson-Martinez, J. P.; Diener, C.; Levine, A. E.; Wilmanski, T.; Suskind, D. L.; Ralevski, A.; Hadlock, J.; Magis, A. T.; Hood, L.; Rappaport, N.; Gibbons, S. M.
10.1101/2023.03.04.531100 — systems biology — Posted on 2024-03-09
3770 Mitochondrial Raf1 Regulates Glutamine Catabolism
Shanderson, R. L.; Ferguson, I. D.; Siprashvili, Z.; Ducoli, L.; Li, A.; Miao, W.; Srinivasan, S.; Velasco, M. G.; Li, Y.; Ye, J.; Khavari, P.
10.1101/2024.03.08.581297 — cancer biology — Posted on 2024-03-09
3773 A TLR7 Agonist Conjugated to a Nanofibrous Peptide Hydrogel as a Potent Vaccine Adjuvant
Euliano, E. M.; Pogostin, B. H.; Agrawal, A.; Yu, M. H.; Baryakova, T. H.; Graf, T. P.; Hartgerink, J. D.; McHugh, K. J.
10.1101/2024.03.07.583938 — bioengineering — Posted on 2024-03-09
3774 Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)
Salinas-Rebolledo, C.; Blesa, J.; Valenzuela-Nieto, G.; Schwefel, D.; Lopez Gonzalez del Rey, N.; Mendez-Ruette, M.; Burkhalter, J.; Batiz, L. F.; Jara, R.; Obeso, J. A.; Chana-Cuevas, P.; Sapkota, G. P.; Rojas-Fernandez, A.
10.1101/2024.03.08.584142 — biochemistry — Posted on 2024-03-09
3777 Effect of pH on the thermostability and redox properties of cytochrome c552 from Wolinella succinogenes
Mordido, V. H.; Carepo, M. S. P.; Cordas, C. M.; Paul, N.; Simon, J.; Moura, I.; Pauleta, S. R.
10.1101/2024.03.09.584216 — biochemistry — Posted on 2024-03-09
3781 Using RNA-targeting CRISPR-Cas13 and engineered U1 systems to reduce ABCA4 splice variants in Stargardt disease
Liu, R. H.-C.; Urrutia-Cabrera, D.; Westin, I. M.; Golovleva, I.; Liu, G.-S.; Kumar, S.; McLenachan, S.; Chen, F. K.; Hsu, F.-T.; Edwards, T.; Martin, K. R.; Cheng, A.; Wong, R. C.
10.1101/2024.03.08.584155 — molecular biology — Posted on 2024-03-09
3783 Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex
Maitland, M. E. R.; Onea, G.; Owens, D. D. G.; Gonga-Cave, B. C.; Wang, X.; Arrowsmith, C. H.; Barsyte-Lovejoy, D.; Lajoie, G. A.; Schild-Poulter, C.
10.1101/2024.03.08.584134 — molecular biology — Posted on 2024-03-09
3784 Botrytis cinerea detoxifies the sesquiterpenoid phytoalexin rishitin through multiple metabolizing pathways
Bulasag, A. S.; Ashida, A.; Miura, A.; Pring, S.; Kuroyanagi, T.; Camagna, M.; Tanaka, A.; Sato, I.; Chiba, S.; Ojika, M.; Takemoto, D.
10.1101/2024.03.08.584175 — microbiology — Posted on 2024-03-09
3785 Molecular Mimicry as a Mechanism of Viral Immune Evasion and Autoimmunity
Maguire, C.; Wang, C.; Ramasamy, A.; Fonken, C.; Morse, B.; Lopez, N.; Wylie, D.; Melamed, E.
10.1101/2024.03.08.583134 — microbiology — Posted on 2024-03-09
3787 High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains
Loes, A. N.; Tarabi, R. A. L.; Huddleston, J.; Touyon, L.; Wong, S. S.; Cheng, S. M.; Leung, N. H.; Hannon, W. W.; Bedford, T.; Cobey, S.; Cowling, B. J.; Bloom, J. D.
10.1101/2024.03.08.584176 — microbiology — Posted on 2024-03-09
3788 Transcriptional plasticity of virulence genes provides malaria parasites with greateradaptive capacity for avoiding host immunity
Florini, F.; Visone, J. E.; Hadjimichael, E.; Malpotra, S.; Nötzel, C.; Kafsack, B. F. C.; Deitsch, K. W.
10.1101/2024.03.08.584127 — microbiology — Posted on 2024-03-09
3789 Antimicrobial Resistance in Diverse Urban Microbiomes: Uncovering Patterns and Predictive Markers
Toscan, R. B.; Subramanian, B.; Stomma, P.; Łabaj, P. P.; Lesinski, W.; Rudnicki, W.
10.1101/2024.03.08.584116 — microbiology — Posted on 2024-03-09
3790 Culture- and genome-based characterization of a tripartite interaction between patescibacterial epibionts, methylotrophic proteobacteria, and a jumbo phage in freshwater ecosystems
Buderka, F.; Lopez-Garcia, P.; Deschamps, P.; Krupovic, M.; Gutierrez-Preciado, A.; Ciobanu, M.; Bertolino, P.; David, G.; Moreira, D.; Jardillier, L.
10.1101/2024.03.08.584096 — microbiology — Posted on 2024-03-09
3791 Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution
Zhang, Z. J.; Cole, C. G.; Coyne, M.; Lin, H.; Dylla, N.; Smith, R. C.; Waligurski, E.; Ramaswamy, R.; Woodson, C.; Burgo, V.; Little, J.; Moran, D.; Rose, A.; McMillin, M.; Mcspadden, E.; Sundararajan, A.; Sidebottom, A.; Pamer, E. G.; Comstock, L. E.
10.1101/2024.03.08.584156 — microbiology — Posted on 2024-03-09
3795 Transient destabilization of whole brain dynamics induced by DMT
Piccinini, J.; Sanz Perl, Y.; Pallavicini, C.; Deco, G.; Kringelbach, M. L.; Nutt, D.; Carhart-Harris, R.; Timmermann, C.; Tagliazucchi, E.
10.1101/2024.01.26.577435 — neuroscience — Posted on 2024-03-09
3797 Highly Dynamic and Sensitive NEMOer Calcium Indicators for Imaging ER Calcium Signals in Excitable Cells
Gu, W.; Chen, J.-H.; Zhang, Y.; Wang, Z.; Li, J.; Wang, S.; Zhang, H.; Jiang, A.; Zhong, Z.; Zhang, J.; Xi, C.; Hou, T.; Gill, D. L.; Li, D.; Mu, Y.; Wang, S.-Q.; Tang, A.-H.; Wang, Y.
10.1101/2024.03.08.583332 — synthetic biology — Posted on 2024-03-09
3799 Empowering High Throughput Screening of 3D Models: Automated Dispensing of Cervical and Endometrial Cancer Cells
Seymour, S.; Cadena, I.; Johnson, M.; Jenne, M.; Adem, I.; Frankovic, R.; Spence, D.; Haddadin, A.; Fogg, K.
10.1101/2024.03.06.583783 — bioengineering — Posted on 2024-03-09
3800 Combining Cell-Intrinsic and -Extrinsic Resistance to HIV-1 By Engineering Hematopoietic Stem Cells for CCR5 Knockout and B Cell Secretion of Therapeutic Antibodies
Feist, W. N.; Luna, S. E.; Ben-Efraim, K.; Filsinger Interrante, M. V.; Amorin, N. A.; Johnston, N. M.; Bruun, T. U. J.; Ghanim, H. Y.; Lesch, B. J.; Dudek, A. M.; Porteus, M. H.
10.1101/2024.03.08.583956 — bioengineering — Posted on 2024-03-09
3804 Engulfment of viable neurons by reactive microglia in prion diseases
Makarava, N.; Safadi, T.; Mychko, O.; Pandit, N. P.; Molesworth, K.; Baiardi, S.; Zhang, L.; Parchi, P.; Baskakov, I. V.
10.1101/2024.03.06.583759 — neuroscience — Posted on 2024-03-09
3805 Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis
Nguyen, B. A.; Singh, V.; Afrin, S.; Singh, P.; Pekala, M.; Ahmed, Y.; Pedretti, R.; Canepa, J.; Lemoff, A.; Kluve-Beckerman, B.; Wydorski, P.; Chhapra, F.; Saelices, L.
10.1101/2024.03.08.582936 — biophysics — Posted on 2024-03-09
3807 Far-red light increases maize volatile emissions in response to volatile cues from neighboring plants
Escobar-Bravo, R.; Schimmel, B. C.; Zhang, Y.; Wang, L.; Robert, C. A.; Glauser, G.; Ballare, C. L.; Erb, M.
10.1101/2022.09.12.507519 — plant biology — Posted on 2024-03-09
3810 Floral scent emission of Epiphyllum oxypetalum: identification of a novel cytosol-localized geraniol biosynthesis pathway
Zhang, Y.; Zhang, Y.; Tian, Q.; Wei, L.; Zhu, T.; Zhou, Z.; Wang, J.; Liu, Z.; Tang, W.; Xiao, H.; Liu, M.; Li, T.; Sun, Q.
10.1101/2023.11.26.568706 — plant biology — Posted on 2024-03-09
3816 Genomic fingerprints of the world's soil ecosystems
Graham, E. B.; Garayburu-Caruso, V. A.; Wu, R.; Zheng, J.; McClure, R.; Jones, G.
10.1101/2023.11.02.563126 — ecology — Posted on 2024-03-09
3817 Dysregulated alveolar epithelial cell progenitor function and identity in Hermansky-Pudlak syndrome pulmonary fibrosis
Wang, J. Y.; Michki, N. S.; Sitaraman, S.; Banaschewski, B. J.; Lin, S. M.; Katzen, J. B.; Basil, M. C.; Cantu, E.; Zepp, J. A.; Frank, D. B.; Young, L. R.
10.1101/2023.06.17.545390 — cell biology — Posted on 2024-03-09
3819 Using the pan-genomic framework for the discovery of genomic islands in the haloarchaeon Halorubrum ezzemoulense
Feng, Y.; Arsenault, D.; Louyakis, A. S.; Altman-Price, N.; Gophna, U.; Papke, R. T.; Gogarten, J. P.
10.1101/2023.10.13.561781 — microbiology — Posted on 2024-03-09
3821 Cataloging Viral Diversity from Nonaxenic Terrestrial Cyanobacteria Cultures
Ettinger, C. L.; Paul, S. R.; Flores, N.; Ward, R. D.; Pietrasiak, N.; Stajich, J. E.
10.1101/2022.12.14.520320 — microbiology — Posted on 2024-03-09
3822 Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis
Horisberger, A.; Griffith, A.; Keegan, J.; Arazi, A.; Pulford, J.; Murzin, E.; Howard, K.; Hancock, B.; Fava, A.; Sasaki, T.; Ghosh, T.; Inamo, J.; Beuschel, R.; Cao, Y.; Preisinger, K.; Gutierrez-Arcelus, M.; Eisenhaure, T. M.; Guthridge, J.; Hoover, P. J.; Dall'Era, M.; Wofsy, D.; Kamen, D. L.; Kalunian, K. C.; Furie, R.; Belmont, M.; Izmirly, P.; Clancy, R.; Hildeman, D.; Woodle, E. S.; Apruzzese, W.; McMahon, M. A.; Grossman, J.; Barnas, J. L.; Payan-Schober, F.; Ishimori, M.; Weisman, M.; Kretzler, M.; Berthier, C. C.; Hodgin, J. B.; Demeke, D. S.; Putterman, C.; Accelerating Medicines Pa
10.1101/2024.01.14.575609 — immunology — Posted on 2024-03-09
3825 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making
Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.
10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-03-09
3826 Sculpting New Visual Categories into the Human Brain
Iordan, M. C.; Ritvo, V. J. H.; Norman, K. A.; Turk-Browne, N. B.; Cohen, J. D.
10.1101/2020.10.14.339853 — neuroscience — Posted on 2024-03-09
3828 Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues
Shin, T. W.; Wang, H.; Zhang, C.; An, B.; Lu, Y.; Zhang, E.; Lu, X.; Karagiannis, E.; Kang, J. S.; Emenari, A.; Symvoulidis, P.; Asano, S.; Lin, L.; Costa, E.; IMAXT Grand Challenge Consortium, ; Marblestone, A. H.; Kasthuri, N.; Tsai, L.-H.; Boyden, E.
10.1101/2024.03.07.583776 — neuroscience — Posted on 2024-03-09
3832 Spray-induced gene silencing (SIGS) as a tool for the management of Pine Pitch Canker forest disease
Bocos Asenjo, I. T.; Amin, H.; Mosquera, S.; Diez Hermano, S.; Ginesy, M.; Diez, J. J.; Nino Sanchez, J.
10.1101/2024.03.05.583474 — plant biology — Posted on 2024-03-09
3834 Gene Trajectory Inference for Single-cell Data by Optimal Transport Metrics
Qu, R.; Cheng, X.; Sefik, E.; Stanley, J. S.; Landa, B.; Strino, F.; Platt, S.; Garritano, J.; Odell, I.; Coifman, R.; Flavell, R.; Myung, P.; Kluger, Y.
10.1101/2022.07.08.499404 — bioinformatics — Posted on 2024-03-09
3835 Assessing computational predictions of antimicrobial resistance phenotypes from microbial genomes
Hu, K.; Meyer, F.; Deng, Z.-L.; Asgari, E.; Kuo, T.-H.; Münch, P. C.; McHardy, A. C.
10.1101/2024.01.31.578169 — bioinformatics — Posted on 2024-03-09
3836 ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis
Yammine, K. M.; Abularach, S. M.; Kim, S.-y.; Bikovtseva, A. A.; Lilianty, J.; Butty, V. L.; Schiavoni, R. P.; Bateman, J. F.; Lamande, S. R.; Shoulders, M. D.
10.1101/2023.10.19.562780 — genetics — Posted on 2024-03-09
3837 Developmental trajectories of EEG aperiodic and periodic power: Implications for understanding thalamocortical development during infancy.
Wilkinson, C. L.; Yankowitz, L.; Chao, J. Y.; Gutierrez, R.; Rhoades, J. L.; Shinnar, S.; Purdon, P.; Nelson, C.
10.1101/2023.07.21.550114 — neuroscience — Posted on 2024-03-09
3840 A direct experimental test of Ohno's hypothesis
Mihajlovic, L.; Iyengar, B. R.; Baier, F.; Barbier, I.; Iwaszkiewicz, J.; Zoete, V.; Wagner, A.; Schaerli, Y.
10.1101/2023.09.25.559237 — evolutionary biology — Posted on 2024-03-09
3841 Peptidyl-tRNA hydrolysis rate influences the efficiency of nonsense-mediated mRNA decay
Kolakada, D.; Fu, R.; Biziaev, N.; Shuvalov, A.; Lore, M.; Campbell, A. E.; Cortazar, M. A.; Sajek, M. P.; Hesselberth, J. R.; Mukherjee, N.; Alkalaeva, E.; Jagannathan, S.
10.1101/2024.01.10.575080 — molecular biology — Posted on 2024-03-09
3844 Predictive Coding Networks for Temporal Prediction
Millidge, B.; Tang, M.; Osanlouy, M.; Harper, N. S.; Bogacz, R.
10.1101/2023.05.15.540906 — neuroscience — Posted on 2024-03-09
3845 Mapping patterns of thought onto brain activity during movie-watching
Wallace, R. S.; Mckeown, B.; Goodall-Halliwell, I.; Chitiz, L.; Forest, P.; Karapanagiotidis, T.; Mulholland, B.; Turnbull, A. G.; Vanderwal, T.; Hardikar, S.; Alam, T. G.; Bernhardt, B.; Wang, H.-T.; Strawson, W.; Milham, M.; Xu, T.; Margulies, D.; Poerio, G. L.; Jefferies, E. S.; Skipper, J. I.; Wammes, J.; Leech, R.; Smallwood, J.
10.1101/2024.01.31.578244 — neuroscience — Posted on 2024-03-09
3847 Live microscopy of multicellular spheroids with the multi-modal near-infrared nanoparticles reveals differences in oxygenation gradients
Debruyne, A. C.; Okkelman, I. A.; Heymans, N.; Pinheiro, C.; Hendrix, A.; Nobis, M.; Borisov, S. M.; Dmitriev, R. I.
10.1101/2023.12.11.571110 — cancer biology — Posted on 2024-03-09
3849 nanoFeatures: a cross-platform application to characterize nanoparticles from super-resolution microscopy images
Izquierdo-Lozano, C.; van Noort, N.; van Veen, S.; Tholen, M. M. E.; Grisoni, F.; Albertazzi, L.
10.1101/2024.02.12.579898 — bioinformatics — Posted on 2024-03-09
3850 Signatures of transposon-mediated genome inflation, host specialization, and photoentrainment in Entomophthora muscae and allied entomophthoralean fungi
Stajich, J. E.; Lovett, B.; Lee, E.; Macias, A. M.; Hajek, A. E.; de Bivort, B. L.; Kasson, M. T.; De Fine Licht, H. H.; Elya, C.
10.1101/2023.09.13.557621 — genomics — Posted on 2024-03-09
3855 Prevalence and diversity of TAL effector-like proteins in fungal endosymbiotic Mycetohabitans spp.
Carpenter, S. C. D.; Bogdanove, A. J.; Abbot, B.; Stajich, J. E.; Uehling, J.; Lovett, B.; Kasson, M. T.; Carter, M. E.
10.1101/2023.10.16.562584 — microbiology — Posted on 2024-03-09
3856 Constructing networks for comparison of collagen types
Wesp, V.; Scholz, L.; Ziermann-Canabarro, J. M.; Schuster, S.; Stark, H.
10.1101/2023.08.25.554753 — systems biology — Posted on 2024-03-09
3858 Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey
Sidous, M.; Cubaynes, S.; Gimenez, O.; Drouet-Hoguet, N.; Dray, S.; Bollache, L.; Madhlamoto, D.; Ngwenya, N. A.; Fritz, H.; Valeix, M.
10.1101/2023.11.08.566247 — ecology — Posted on 2024-03-09
3859 Engineering an in vitro retinothalamic nerve model
Amos, G.; Ihle, S. J.; Clement, B. F.; Duru, J.; Girardin, S.; Maurer, B.; Delipinar, T.; Varos, J.; Ruff, T.
10.1101/2024.03.06.582645 — neuroscience — Posted on 2024-03-08
3860 Striatal Dopamine Modulates Temporal Surprise P3a
Whitaker, G. A.; Schwartze, M.; Martin, S.; Astudillo, A.; Silverdale, M.; El-Deredy, W.; Kotz, S. A.
10.1101/2024.03.05.583515 — neuroscience — Posted on 2024-03-08
3861 Midbrain Dopaminergic Neuron Development is Regulated by Two Molecularly Distinct Subtypes of Radial Glia Cells
Asgrimsdottir, E. S.; Bassini, L. F.; di Val Cervo, P. R.; Gyllborg, D.; Pastor, C. P.; Lee, K.; Grigsby, C. L.; Islam, S.; Lönnerberg, P.; Villaescusa, C.; Salto, C.; Linnarsson, S.; La Manno, G.; Toledo, E. M.; Arenas, E.
10.1101/2024.03.08.584031 — neuroscience — Posted on 2024-03-08
3862 Blocking Src-PSD-95 interaction rescues glutamatergic signaling dysregulation in schizophrenia.
Featherstone, R.; Li, H.; Sengar, A.; Borgmann-Winter, K. E.; Hahn, C.-G.; Melnychenko, O.; Crown, L. M.; Gifford, R. L.; Amirfathi, F.; Banerjee, A.; Parekh, K.; Heller, M.; Zhang, W.; Marc, A. D.; Salter, M. W.; Siegel, S. J.
10.1101/2024.03.08.584132 — neuroscience — Posted on 2024-03-08
3863 Neurobiological Changes Across Pregnancy: A Longitudinal Investigation
Niu, Y.; Conrad, B. N.; Camacho, M. C.; Ravi, S.; Piersiak, H. A.; Bailes, L. G.; Barnett, W.; Manhard, M. K.; Cole, D. A.; Clayton, E. W.; Osmundson, S. S.; Smith, S. A.; Kujawa, A.; Humphreys, K. L.
10.1101/2024.03.08.584178 — neuroscience — Posted on 2024-03-08
3865 Monitoring myelin lipid composition and structure of myelinated fibers reveals a maturation delay in CMT1A
Capodivento, G.; Camera, M.; Liessi, N.; Trada, A.; Debellis, D.; Schenone, A.; Armirotti, A.; Visigalli, D.; Nobbio, L.
10.1101/2024.03.08.581205 — neuroscience — Posted on 2024-03-08
3866 The auditory midbrain mediates tactile vibration sensing
Huey, E. L.; Turecek, J.; Delisle, M. M.; Mazor, O.; Romero, G. E.; Dua, M.; Sarafis, Z. K.; Hobble, A.; Booth, K. T.; Goodrich, L. V.; Corey, D. P.; Ginty, D. D.
10.1101/2024.03.08.584077 — neuroscience — Posted on 2024-03-08
3867 Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing
Wang, M.; Krueger, J. B.; Gilkey, A. K.; Stelljes, E. M.; Kluesner, M. G.; Pomeroy, E. J.; Skeate, J. G.; Slipek, N. J.; Lahr, W. S.; Claudio Vazquez, P. N.; Zhao, Y.; Eaton, E. J.; Laoharawee, K.; Webber, B. R.; Moriarity, B. S.
10.1101/2024.03.05.582637 — bioengineering — Posted on 2024-03-08
3869 Regional Plasmodium falciparum subpopulations and malaria transmission connectivity in Africa were detected with an enlarged panel of genome-wide microsatellite loci
Demba, M. A.; Kamau, E.; Raman, J.; Mane, K.; Amenga-Etego, L.; Apinjo, T.; Ishengoma, D. J.; Golassa, L.; Maiga, O.; Ghansa, A.; Bouyou-Akotet, M.; Yavo, W.; Randrianarivelojosia, M.; Diop, F. M.; Oriero, E. C.; Jeffries, D.; D'Alessandro, U.; Djimde, A.; Amambua-Ngwa, A.
10.1101/2024.03.08.584049 — genomics — Posted on 2024-03-08
3870 Molecular insights into the atypical activation mechanism of GPR156 in maintaining auditory function
Ma, X.; Chen, L.-N.; Liao, M.; Zhang, L.; Xi, K.; Guo, J.; Shen, C.; Cai, P.; Shen, Q.; Qi, J.; Zhang, H.; Zang, S.-K.; Dong, Y.-J.; Miao, L.; Qin, J.; Ji, S.-Y.; Li, Y.; Liu, J.; Mao, C.; Zhang, Y.; Chai, R.
10.1101/2024.03.07.581839 — molecular biology — Posted on 2024-03-08
3873 A comparison between full-length 16S rRNA Oxford Nanopore sequencing and Illumina V3-V4 16S rRNA sequencing in head and neck cancer tissues
Yeo, K.; Connell, J.; Bouras, G.; Smith, E.; Murphy, W.; Hodge, J.-C.; Krishnan, S.; Wormald, P.-J.; Valentine, R.; Psaltis, A.; Vreugde, S.; Fenix, K.
10.1101/2024.03.08.584026 — microbiology — Posted on 2024-03-08
3875 Identification of Druggable Binding Sites and Small Molecules as Modulators of TMC1
De-la-Torre, P.; Martinez-Garcia, C.; Gratias, P.; Mun, M.; Santana, P.; Akyuz, N.; Gonzalez, W.; Indzhykulian, A. A.; Ramirez, D.
10.1101/2024.03.05.583611 — neuroscience — Posted on 2024-03-08
3876 In silico genomic surveillance by CoVerage predicts and characterizes SARS-CoV-2 Variants of Interest
Norwood, K.; Deng, Z.-L.; Reimering, S.; Robertson, G.; Foroughmand-Araabi, M.-H.; Goliaei, S.; Hoelzer, M.; McHardy, A. C.
10.1101/2024.03.07.583829 — bioinformatics — Posted on 2024-03-08
3877 Synth4bench: a framework for generating synthetic genomics data for the evaluation of tumor-only somatic variant calling algorithms
Fragkouli, S.-C.; Pechlivanis, N.; Anastasiadou, A.; Karakatsoulis, G.; Orfanou, A.; Kollia, P.; Agathangelidis, A.; Psomopoulos, F. E.
10.1101/2024.03.07.582313 — bioinformatics — Posted on 2024-03-08
3879 Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules
Ashkarran, A. A.; Gharibi, H.; Modaresi, S. M.; Sayadi, M.; Jafari, M.; Lin, Z.; Ritz, D.; Kakhniashvili, D.; Sun, L.; Landry, M. P.; Dibavar, A. S.; Mahmoudi, M.
10.1101/2024.03.06.582595 — bioengineering — Posted on 2024-03-08
3880 Development of a new genotype-phenotype linked antibody screening system
Watanabe, T.; Hata, H.; Mochizuki, Y.; Yokoyama, F.; Hasegawa, T.; Kumar, N.; Kurosaki, T.; Ohara, O.; Fukuyama, H.
10.1101/2024.03.06.581777 — bioengineering — Posted on 2024-03-08
3881 Conformational switch of a peptide provides a novel strategy to design peptide loaded porous organic polymer for Pyroptosis pathway mediated cancer therapy
Chattopahyay, K.; Mishra, S.; Sannigrahi, A.; Ruidas, S.; Chatterjee, S.; Roy, K.; Mishra, D.; Maity, B. K.; Paul, R.; Das Saha, K.; Bhaumik, A.
10.1101/2024.03.05.583621 — biochemistry — Posted on 2024-03-08
3885 Insects visit Fusarium xyrophilum pseudoflowers on the host Xyris surinamensis (Xyridaceae) and carry fungal DNA on their bodies
Cruz, T. J. T.; Cofer, T. M.; Kaminsky, L. M.; Re, L. A.; Vaughn, A.; Johnson, J. R.; Tumlinson, J. H.; Laraba, I.; Proctor, R. H.; Kim, H.-S.; Bell, T. H.; Aime, M. C.; Skvarla, M. J.; Geiser, D. M.
10.1101/2024.03.05.583517 — ecology — Posted on 2024-03-08
3888 Overexpression of barley heat stress transcription factor HvHsfA6a provide thermotolerance by thermopriming
Chaudhary, R.; Baliyan, S.; Sirohi, P.; Singh, S.; Mishra, S. K.; Rajkumar, M. S.; Saini, S. S.; Germain, H.; Sircar, D.; Chauhan, H.
10.1101/2024.03.06.583688 — molecular biology — Posted on 2024-03-08
3889 Released Bacterial ATP Shapes Local and Systemic Inflammation during Abdominal Sepsis
Spari, D.; Schmid, A.; Sanchez-Taltavull, D.; Murugan, S.; Keller, K.; Ennaciri, N.; Salm, L.; Stroka, D.; Beldi, G.
10.1101/2024.03.07.583973 — microbiology — Posted on 2024-03-08
3892 Highly multiplexed design of an allosteric transcription factor to sense novel ligands
Nishikawa, K. K.; Chen, J.; Acheson, J. F.; Harbaugh, S. V.; Huss, P.; Frenkel, M.; Novy, N.; Sieren, H. R.; Lodewyk, E. C.; Lee, D. H.; Chavez, J. L.; Fox, B. G.; Raman, S.
10.1101/2024.03.07.583947 — synthetic biology — Posted on 2024-03-08
3899 Large contribution of repeats to genetic variation in a transmission cluster of Mycobacterium tuberculosis
Stritt, C.; Reitsma, M.; Goig, G. A.; Dötsch, A.; Borrell, S.; Beisel, C.; Brites, D.; Gagneux, S.
10.1101/2024.03.08.584093 — genomics — Posted on 2024-03-08
3902 PPFlow: Target-aware Peptide Design with Torsional Flow Matching
Lin, H.; Zhang, O.; Zhao, H.; Jiang, D.; Wu, L.; Liu, Z.; Huang, Y.; Li, S. Z.
10.1101/2024.03.07.583831 — molecular biology — Posted on 2024-03-08
3904 Comparative analysis of mouse strains for in vivo reprogramming
Pico, S.; Vilchez Acosta, A.; de Sousa, J. A.; Maza, M. d. C.; Parras, A.; Desdin Mico, G.; Mrabti, C.; Yacoub Maroun, C.; Branchina, C.; von Meyenn, F.; Ocampo, A.
10.1101/2024.03.08.584074 — molecular biology — Posted on 2024-03-08
3905 The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target.
Alharthi, R.; Sueiro-Olivares, M.; Storer, I.; Alshammri, H.; Scott, J.; Al-Shidhani, R.; Fortune-Grant, R.; Bignell, E.; Tabernero, L.; Bromley, M.; Zhao, C.; Amich, J.
10.1101/2024.03.08.582945 — microbiology — Posted on 2024-03-08
3906 Unicellular cyanobacteria rely on sodium energetics to fix N2
Tang, S.; Cheng, X.; Liu, Y.; Liu, L.; Liu, D.; Yan, Q.; Zhu, J.; Zhou, J.; Hammerschmidt, K.; Cai, Z.
10.1101/2024.03.08.584021 — microbiology — Posted on 2024-03-08
3908 Diverse fox circovirus (Circovirus canine) variants circulate at high prevalence in grey wolves (Canis lupus)
Canuti, M.; King, A. V. L.; Franzo, G.; Cluff, H. D.; Larsen, L. E.; Fenton, H.; Dufour, S. C.; Lang, A. S.
10.1101/2024.03.08.584028 — microbiology — Posted on 2024-03-08
3909 Antigenicity assessment of SARS-CoV-2 saltation variant BA.2.87.1
Yang, S.; Yu, Y.; Jian, F.; Yisimayi, A.; Song, W.; Liu, J.; Wang, P.; Xu, Y.; Wang, J.; Niu, X.; Yu, L.; Wang, Y.; Shao, F.; Jin, R.; Wang, Y.; Cao, Y.
10.1101/2024.03.07.583823 — immunology — Posted on 2024-03-08
3910 Resolution of SARS-CoV-2 infection in human lung tissues is driven by extravascular CD163+ monocytes
Kenney, D. J.; O'Connell, A. K.; Tseng, A. E.; Turcinovic, J.; Sheahan, M. L.; Nitido, A. D.; Montanaro, P.; Gertje, H. P.; Ericsson, M.; Connor, J. H.; Vrbanac, V.; Crossland, N. A.; Harly, C.; Balazs, A. B.; Douam, F.
10.1101/2024.03.08.583965 — immunology — Posted on 2024-03-08
3913 Lack of TGFβ signaling competency predicts immune poor cancer conversion to immune rich and response to checkpoint blockade
Moore, J.; Gkantalis, J.; Guix, I.; Chou, W.; Yuen, K.; Lazar, A.; Spitzer, M. H.; combes, a.; Barcellos-Hoff, M. H.
10.1101/2024.03.06.583752 — cancer biology — Posted on 2024-03-08
3915 Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues
Shin, T. W.; Wang, H.; Zhang, C.; An, B.; Lu, Y.; Zhang, E.; Lu, X.; Karagiannis, E.; Kang, J. S.; Emenari, A.; Symvoulidis, P.; Asano, S.; Lin, L.; Costa, E.; IMAXT Grand Challenge Consortium, ; Marblestone, A. H.; Kasthuri, N.; Tsai, L.-H.; Boyden, E.
10.1101/2024.03.07.583776 — bioengineering — Posted on 2024-03-08
3916 Neurophysiological trajectories in Alzheimer's disease progression
Kudo, K.; Ranasinghe, K. G.; Morise, H.; Syed, F.; Sekihara, K.; Rankin, K. P.; Miller, B. L.; Kramer, J.; Rabinovici, G.; Vossel, K.; Kirsch, H. E.; Nagarajan, S.
10.1101/2023.05.18.541379 — neuroscience — Posted on 2024-03-08
3917 Decoding auditory working memory content from EEG aftereffects of auditory-cortical TMS
Uluc, I.; Daneshzand, M.; Jas, M.; Kotlarz, P.; Lankinen, K.; Fiedler, J.; Mamashli, F.; Pajankar, N.; Turpin, T.; Navarro de Lara, L.; Sundaram, P.; Raij, T.; Nummenmaa, A.; Ahveninen, J.
10.1101/2024.03.04.583379 — neuroscience — Posted on 2024-03-08
3918 Robust Methods For Quantifying Neuronal Morphology And Molecular Signaling Reveal That Psychedelics Do Not Induce Neuroplasticity
Boltaev, U.; Park, H. W.; Brown, K. R.; Delgado, M.; Wu, J.; Diaz-Pacheco, B. N.; Botero Pinzon, M.; He, K.; Ahern, E.; Goldshmid, N.; Simpson, E. H.; Sames, D.
10.1101/2024.03.04.583022 — neuroscience — Posted on 2024-03-08
3919 Testing a Method for Quantifying Microplastic Content in Mytilus californianus
Sidhu, A.; Sun, W.; Helal, M.; Gupta, A.; Mittal, A.; Ramanathan, S.; Thakur, M.; Jain, B.; Wang, D.; Benson, A.; Adams, C. T.
10.1101/2024.03.04.583441 — zoology — Posted on 2024-03-08
3920 Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling
Zuo, M.; Zhang, S.; Chen, S.; Xiang, Y.; Yuan, Y.; Li, T.; Yang, W.; Wang, Z.; He, Y.; Li, W.; Feng, W.; Chen, N.; Yang, Y.; Zeng, Y.; Mao, Q.; Chen, M.; Liu, y.
10.1101/2024.03.05.581575 — cancer biology — Posted on 2024-03-08
3921 The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma
Hruby, L.; Scharov, K.; Delaidelli, A.; Picard, D.; Dunham, C.; Lewandowska, O.; Reiff, T.; Larcher, M.; Pouponnot, C.; Sorensen, P. H.; Rotblat, B.; Reifenberger, G.; Remke, M.; Leprivier, G.
10.1101/2024.03.06.583558 — cancer biology — Posted on 2024-03-08
3922 Single-cell analysis of an engineered organoid-based model of pancreatic cancer identifies hypoxia as a contributing factor in the determination of transcriptional subtypes
Landon-Brace, N.; Innes, B. T.; Latour, S.; Cadavid, J. L.; Co, I. L.; Tam, C.; Nowlan, F.; Drissler, S.; Notta, F.; Jackson, H. W.; Bader, G. D.; McGuigan, A. P.
10.1101/2024.03.05.583412 — cancer biology — Posted on 2024-03-08
3923 Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP signaling in dormant disseminated uveal melanoma
Kadamb, R.; Anton, M. L.; Purwin, T. J.; Chua, V.; Seeneevassen, L.; Teh, J.; Nieto, M. A.; Sato, T.; Terai, M.; Roman, S.; de Koning, L.; Zheng, D.; Aplin, A. E.; Aguirre-Ghiso, J.
10.1101/2024.03.05.583565 — cancer biology — Posted on 2024-03-08
3924 A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma
Sussman, J. H.; Oldridge, D. A.; Yu, W.; Chen, C.-H.; Zellmer, A. M.; Rong, J.; Parvaresh-Rizi, A.; Thadi, A.; Xu, J.; Bandyopadhyay, S.; Sun, Y.; Wu, D.; Hunter, C. E.; Brosius, S.; Ahn, K. J.; Baxter, A. E.; Koptyra, M. P.; Vanguri, R.; McGrory, S.; Resnick, A. C.; Storm, P. B.; Amankulor, N. M.; Santi, M.; Viaene, A. N.; Zhang, N.; De Raedt, T.; Cole, K.; Tan, K.
10.1101/2024.03.06.583588 — cancer biology — Posted on 2024-03-08
3925 Post-death Vesicles of Senescent Bone Marrow Mesenchymal Stromal Polyploids Promote Macrophage Aging and Breast Cancer
Xie, B.; Fan, M.; Wang, C. X.; Zhang, Y.; Xu, S.; Mizenko, R.; Lin, T.-y.; Duan, Y.; Zhang, Y.; Huang, J.; Berg, J. I.; Wu, D.; Li, A.; Hao, D.; Gao, K.; Sun, Y.-h.; Tepper, C. G.; Carney, R. P.; Li, Y.; Wang, A.; Gong, Q.; Daly, M.; Jao, L.-E.; Monjazeb, A. M.; Fierro, F. A.; Li, J. J.
10.1101/2024.03.06.583755 — cancer biology — Posted on 2024-03-08
3927 Modeling the genomic complexity of human cancer using Cas12a mice
Hebert, J. D.; Xu, H.; Tang, Y. J.; Ruiz, P. A.; Detrick, C.; Wang, J.; Hughes, N. W.; Donosa, O.; Andrejka, L.; Karmakar, S.; Aboiralor, I.; Cong, L.; Sage, J.; Petrov, D.; Winslow, M. M.
10.1101/2024.03.07.583774 — cancer biology — Posted on 2024-03-08
3928 Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis
Hebert, J. D.; Tang, Y. J.; Andrejka, L.; Lopez, S. S.; Petrov, D. A.; Boross, G.; Winslow, M. M.
10.1101/2024.03.07.583981 — cancer biology — Posted on 2024-03-08
3929 De novo detection of somatic variants in long-read single-cell RNA sequencing data
Dondi, A.; Borgsmüller, N.; Ferreira, P. F.; Haas, B. J.; Jacob, F.; Heinzelmann-Schwarz, V.; Tumor Profiler Consortium, ; Beerenwinkel, N.
10.1101/2024.03.06.583775 — cancer biology — Posted on 2024-03-08
3932 Targeted Long-Read Bisulfite Sequencing for Promoter Methylation Analysis in Severe Preterm Birth
Pereyra, S.; Sardina, A.; Neumann, R.; May, C.; Sapiro, R.; Bertoni, B.; Cappetta, M.
10.1101/2024.03.04.583424 — genetics — Posted on 2024-03-08
3936 Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated transcriptome in human cells
Boehm, V.; Wallmeroth, D.; Wulf, P. O.; Alves, L. G. T.; Popp, O.; Riedel, M.; Wyler, E.; Franitza, M.; Gerbracht, J. V.; Becker, K.; Polkovnychenko, K.; Del Giudice, S.; Benlasfer, N.; Mertins, P.; Landthaler, M.; Gehring, N. H.
10.1101/2024.03.04.583328 — molecular biology — Posted on 2024-03-08
3937 GRASPS: a simple-to-operate translatome technology reveals omics-hidden disease-associated pathways in TDP-43-related amyotrophic lateral sclerosis
Lin, Y.-H.; Dodd, J. E.; Cutillo, L.; Castelli, L. M.; Mihaylov, S. R.; Norris, K.; Higginbottom, A.; Walsh, M. J.; Cooper-Knock, J.; Highley, J. R.; Granata, I.; Evans, C. A.; Guarracino, M. R.; Campbell, S. G.; Dickman, M. J.; Shaw, P. J.; Milo, M.; Hautbergue, G. M.
10.1101/2024.03.04.583294 — molecular biology — Posted on 2024-03-08
3938 Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypoproliferation
Feng, X.; Andersson, T.; Gschwend, J.; Flüchter, P.; Berest, I.; Muff, J. L.; Carchidi, D.; Lechner, A.; de Tenorio, J. C.; Brander, N.; Boehm, U.; Klose, C. S.; Artis, D.; Leinders-Zufall, T.; Zufall, F.; Schneider, C.
10.1101/2024.03.04.583299 — immunology — Posted on 2024-03-08
3939 Integrated stress response associated with dark microglia promotes microglial lipogenesis and contributes to neurodegeneration
Flury, A.; Aljayousi, L.; Aziz, S.; Park, H.-J.; Khakpour, M.; Sandberg, C.; Ibanez, F. G.; Braniff, O.; Deme, P.; McGrath, J. D.; Ngo, T.; Mechler, J.; Ramirez, D. M.; Avnon-Klein, D.; Murray, J. W.; Liu, J.; Haughey, N. J.; Werneburg, S.; Tremblay, M.-E.; Ayata, P.
10.1101/2024.03.04.582965 — neuroscience — Posted on 2024-03-08
3941 Identification of regional astrocyte heterogeneity associated with cuprizone-induced de- and remyelination using spatial transcriptomics
Miedema, A.; Wijering, M. H. C.; Alsema, A.; Gerrits, E.; Meijer, M.; Koster, M.; Wesseling, E. M.; Baron, W.; Eggen, B. J. L.; Kooistra, S. M.
10.1101/2024.03.04.583308 — neuroscience — Posted on 2024-03-08
3942 Unraveling the Genetic Comorbidity Landscape of Alzheimer's Disease
Zhang, X.; Li, D.; Ye, S.; Liu, S.; Ma, S.; Li, M.; Peng, Q.; Hu, L.; Shang, X.; He, M.; Zhang, L.
10.1101/2024.03.05.583453 — neuroscience — Posted on 2024-03-08
3946 Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration.
Schmitd, L. B.; Hafner, H.; Ward, A.; Adib, E. A.; Biscola, N. P.; Kohen, R.; Patel, M.; Williamson, R. E.; Desai, E.; Bennett, J.; Saxman, G.; Athaiya, M.; Wilborn, D.; Shumpert, J.; Zhao, X.-F.; Kawaguchi, R.; Geschwind, D. H.; Hoke, A.; Shrager, P.; Collins, C. A.; Havton, L. A.; Kalinski, A. L.; Giger, R. J.
10.1101/2024.03.04.583374 — neuroscience — Posted on 2024-03-08
3948 Beyond homogeneity: Charting the landscape of heterogeneity in psychiatric electroencephalography
Ebadi, A.; Allouch, S.; Mheich, A.; Tabbal, J.; Kabbara, A.; Robert, G.; Lefebvre, A.; Iftimovici, A.; Rodriguez-Herreros, B.; Chabane, N.; HASSAN, M.
10.1101/2024.03.04.583393 — neuroscience — Posted on 2024-03-08
3953 Zr-labeled N4MU01 radioimmunoconjugates as theranostics against nectin-4 positive triple negative breast cancer
Babeker, H.; Njotu, F. N.; Ketchemen, J. P.; Tikum, A. F.; Doroudi, A.; Nwangele, E.; Uppalapati, M.; Fonge, H.
10.1101/2024.03.04.583420 — pharmacology and toxicology — Posted on 2024-03-08
3954 Effects of access condition on substance use disorder-like phenotypes in male and female rats self-administering MDPV or cocaine
Doyle, M. R.; Beltran, N. M.; Bushnell, M. S.; Syed, M.; Acosta, V.; Desai, M.; Rice, K. C.; Serafine, K. M.; Gould, G. G.; Daws, L. C.; Collins, G. T.
10.1101/2024.03.04.583431 — pharmacology and toxicology — Posted on 2024-03-08
3958 Nociceptive neurons interact directly with gastric cancer cells via a CGRP/Ramp1 axis to promote tumor progression
Zhi, X.; Wu, F.; Qian, J.; Ochiai, Y.; Lian, G.; Malagola, E.; Chen, D.; Ryeom, S. W.; WANG, T. C.
10.1101/2024.03.04.583209 — cancer biology — Posted on 2024-03-08
3967 Client recognition differences between PDI and ERp46 to guide oxidative folding
Saio, T.; Ishii, K.; Matsusaki, M.; Kumeta, H.; Kenemura, S.; Okumura, M.
10.1101/2024.03.04.583432 — biochemistry — Posted on 2024-03-08
3969 Unravelling the effects of individual heterogeneity on connectivity estimates: Insights from Spatial Capture-Recapture modelling
Kervellec, M.; Gimenez, O.; Vanpe, C.; Sentilles, J.; Quenette, P.-Y.; Palazon, S.; Afonso Jordana, I.; Jato, R.; Elosegui Irurtia, M. M.; Milleret, C.
10.1101/2024.03.04.583266 — ecology — Posted on 2024-03-08
3971 De Novo TANGLED1 Recruitment to Aberrant Cell Plate Fusion Sites in Maize
Uyehara, A. N.; Diep, B. N.; Allsman, L. A.; Gayer, S. G.; Martinez, S. E.; Kim, J. J.; Agarwal, S.; Rasmussen, C.
10.1101/2024.03.07.583939 — plant biology — Posted on 2024-03-08
3976 k-Means NANI: an improved clustering algorithm for Molecular Dynamics simulations
Chen, L.; Roe, D. R.; Kochert, M.; Simmerling, C.; Miranda Quintana, R. A.
10.1101/2024.03.07.583975 — biophysics — Posted on 2024-03-08
3978 Detection of idiosyncratic gaze fingerprint signatures in humans
Crockford, S. K.; Satta, E.; Severino, I.; Fiacchino, D.; Vitale, A.; Bertelsen, N.; Busuoli, E. M.; Mandelli, V.; Lombardo, M. V.
10.1101/2023.09.18.558217 — neuroscience — Posted on 2024-03-08
3980 Composition can buffer protein dynamics within liquid-like condensates.
Jelenic, S.; Bindics, J.; Czermak, P.; Pillai, B. R.; Ruer, M.; Hoege, C.; Holehouse, A. S.; Saha, S.
10.1101/2022.05.16.492059 — cell biology — Posted on 2024-03-08
3983 Leucine Rich Repeat Kinase 2 is not required for lysozyme expression in intestinal Paneth cells
Tasegian, A.; Dikovskaya, D.; Scott, M.; Helps, T.; Meus, T.; McLean, M. H.; Swamy, M.
10.1101/2024.03.07.582590 — physiology — Posted on 2024-03-08
3984 Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis
Veloso, A.; Slegers, T.; Schoenaker, J.; Demeyer, S.; Van den Bergh, S.; Aertgeerts, M.; Verhoeft, K.; Schoenmaekers, Y.; Meeuws, N.; Bischops, I.; Renard, F.; Boogaerts, L.; Mentens, N.; Gielen, O.; Jacobs, K.; Segers, H.; Cools, J.; Dierickx, D.; Vanden Bempt, M.
10.1101/2024.03.03.583195 — cancer biology — Posted on 2024-03-08
3985 N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine
Wang, C.; Zhao, C.; Xiao, H.; Qiang, J.; Liu, Z.; Gu, J.; Zhang, S.; Li, D.; Zhang, Y.; Burre, J.; Diao, J.; Liu, C.
10.1101/2024.03.04.583437 — biophysics — Posted on 2024-03-08
3988 Feedback modulation of Orai1α and Orai1β protein content mediated by STIM proteins
Nieto-Felipe, J.; Macias-Diaz, A.; Jimenez-Velarde, V.; Lopez, J. J.; Salido, G. M.; Smani, T.; Jardin, I.; Rosado, J. A.
10.1101/2024.03.05.583469 — cell biology — Posted on 2024-03-08
3991 Synphilin-1 as a modulator of aSyn assembly
Lazaro, D.; Amen, T.; Gerhardt, E.; dos Santos, P. P.; Milovanovic, D.; Höglinger, G.; Outeiro, T.
10.1101/2024.03.05.583522 — molecular biology — Posted on 2024-03-08
3992 Antigenic determinants of HAstV-VA1 neutralization and their relevance in the human immune response
Ramirez-Bello, I.; Lopez, T.; Espinosa, R.; Ghosh, A.; Green, K.; Riano-Umbarila, L.; Gaspar-Castillo, C.; Alpuche-Aranda, C.; Lopez, S.; DuBois, R. M.; Arias, C. F.
10.1101/2024.03.05.583477 — microbiology — Posted on 2024-03-08
3993 Sanctuary: A Starship transposon facilitating the movement of the virulence factor ToxA in fungal wheat pathogens
Bucknell, A.; Wilson, H.; Goncalves dos Santos, K. C.; Simpfendorfer, S.; Milgate, A.; Germain, H.; Solomon, P.; Bentham, A.; McDonald, M.
10.1101/2024.03.04.583430 — genomics — Posted on 2024-03-08
3995 Heterogeneous identity, stiffness and growth characterise the shoot apex of Arabidopsis stem cell mutants
Rambaud-Lavigne, L.; Chatterjee, A.; Bovio, S.; Battu, V.; Lavigne, Q.; Gundiah, N.; Boudaoud, A.; Das, P.
10.1101/2023.07.28.550972 — plant biology — Posted on 2024-03-08
3998 Deciphering Peptide-Protein Interactions via Composition-Based Prediction: A Case Study with Survivin/BIRC5
Anindya, A. L.; Olsson, T. N.; Jensen, M.; Garcia-Bonete, M.-J.; Wheatley, S.; Bokarewa, M. I.; Mezzasalma, S. A.; Katona, G.
10.1101/2024.02.12.579763 — bioinformatics — Posted on 2024-03-08
3999 Thermal tolerance traits of individual corals are widely distributed across the Great Barrier Reef
DENIS, H.; Bay, L. K.; Mocellin, V. J. L.; Naugle, M. S.; Lecellier, G.; Purcell, S. W.; Berteaux-Lecellier, V.; Howells, E. J.
10.1101/2024.01.28.576773 — ecology — Posted on 2024-03-08
4003 A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity
Mosharov, E.; Rosenberg, A. M.; Monzel, A. S.; Osto, C. A.; Stiles, L.; Rosoklija, G. B.; Dwork, A. J.; Bindra, S.; Zhang, Y.; Fujita, M.; Mariani, M. B.; Bakalian, M.; Sulzer, D.; De Jager, P.; Menon, V.; Shirihai, O. S.; Mann, J.; Underwood, M.; Boldrini, M.; Thiebaut de Schotten, M. S.; Picard, M.
10.1101/2024.03.05.583623 — neuroscience — Posted on 2024-03-07
4006 Unraveling the Role of MIXL1 Activation in Endoderm Differentiation of Isogenic Human Induced Pluripotent Stem Cells
Osteil, P.; Withey, S.; Santucci, N.; Aryamanesh, N.; Pang, C. N. I.; Salehin, N.; Sun, J.; Qin, A.; Su, J.; Knowles, H.; Cai, Z.; Craft, G.; Graham, M. E.; Li, X. B.; Wolvetang, E. J.; Tam, P. P. L.
10.1101/2024.03.06.583475 — developmental biology — Posted on 2024-03-07
4008 Epstein-Barr Virus Orchestrates Spatial Reorganization and Immunomodulation within the Classic Hodgkin Lymphoma Tumor Microenvironment
Yeo, Y. Y.; Qiu, H.; Bai, Y.; Zhu, B.; Chang, Y.; Yeung, J.; Michel, H. A.; Wright, K. T.; Shaban, M.; Sadigh, S.; Nkosi, D.; Shanmugam, V.; Yiu, S. P. T.; Cramer, P.; Rock, P.; Paczkowska, J.; Stephan, P.; Liao, G.; Wang, H.; Huang, A. Y.; Chen, H.; Frauenfeld, L.; Mitra, B.; Gewurz, B. E.; Schurch, C. M.; Zhao, B.; Nolan, G. P.; Zhang, B.; Shalek, A. K.; Angelo, M.; Mahmood, F.; Ma, Q.; Burack, W. R.; Shipp, M. A.; Rodig, S. J.; Jiang, S.
10.1101/2024.03.05.583586 — cancer biology — Posted on 2024-03-07
4009 Signaling events at TMEM doorways provide potential targets for inhibiting breast cancer dissemination
Surve, C. R.; Duran, C. L.; Ye, X.; Chen, X.; Lin, Y.; Harney, A. S.; Wang, Y.; Sharma, V. P.; Stanley, E. R.; Cox, D.; McAuliffe, J. C.; Entenberg, D.; Oktay, M. H.; Condeelis, J. S.
10.1101/2024.01.08.574676 — cancer biology — Posted on 2024-03-07
4010 Mitotic waves in frog egg extracts: Transition from phase waves to trigger waves
Puls, O.; Ruiz-Reynes, D.; Tavella, F.; Jin, M.; Kim, Y.; Gelens, L.; Yang, Q.
10.1101/2024.01.18.576267 — biophysics — Posted on 2024-03-07
4012 A Foundation Model for Cell Segmentation
Israel, U.; Marks, M.; Dilip, R.; Li, Q.; Yu, C.; Laubscher, E.; Li, S.; Schwartz, M. S.; Pradhan, E.; Ates, A.; Abt, M.; Brown, C.; Pao, E.; Pearson-Goulart, A.; Perona, P.; Gkioxari, G.; Barnowski, R.; Yue, Y.; Van Valen, D. A.
10.1101/2023.11.17.567630 — bioinformatics — Posted on 2024-03-07
4013 Shear Stress Induces a Pro-Inflammatory Phenotype in Human Monocyte-Derived Macrophages
Jui, E.; Kingsley, G.; Pham, H. K.; Singampalli, K.; Birla, R.; Connell, J.; Keswani, S.; Grande-Allen, K. J.
10.1101/2022.12.08.519590 — bioengineering — Posted on 2024-03-07
4014 Behavioral sequences across multiple animal species in the wild share common structural features
Minasandra, P.; Grout, E. M.; Brock, K.; Crofoot, M. C.; Demartsev, V.; Gersick, A. S.; Hirsch, B. T.; Holekamp, K. E.; Johnson-Ulrich, L.; Nayak, A.; Ortega, J.; Roch, M. A.; Strauss, E. D.; Strandburg-Peshkin, A.
10.1101/2024.01.20.576411 — animal behavior and cognition — Posted on 2024-03-07
4016 Transposable elements impact the population divergence of rice blast fungus Magnaporthe oryzae
Lin, L.; Sun, T.; Guo, J.; Lin, L.; Chen, M.; Wang, Z.; Bao, J.-D.; Norvienyeku, J.; Han, Y.; Lu, G.; Rensing, C.; Zheng, H.; Zhong, Z.; Wang, Z.
10.1101/2023.05.12.540556 — evolutionary biology — Posted on 2024-03-07
4017 Amoeboid cells undergo durotaxis with soft end polarized NMIIA
Kang, C.; Chen, P.; Yi, X.; Li, D.; Hu, Y.; Yang, Y.; Cai, H.; Li, B.; Wu, C.
10.1101/2023.04.13.536664 — cell biology — Posted on 2024-03-07
4019 Dendritic voltage imaging maps the biophysical basis of plateau potentials in the hippocampus
Park, P.; Wong-Campos, J. D.; Itkis, D.; Lee, B. H.; Qi, Y.; Davis, H. C.; Grimm, J. B.; Plutkis, S. E.; Lavis, L.; Cohen, A. E.
10.1101/2023.06.02.543490 — neuroscience — Posted on 2024-03-07
4023 Biochemical properties of chromatin domains define genome compartmentalization
Lucini, F.; Petrini, C.; Salviato, E.; Pal, K.; Rosti, V.; Gorini, F.; Santarelli, P.; Quadri, R.; Lembo, G.; Graziano, G.; Di Patrizio Soldateschi, E.; Tagliaferri, I.; Pinatel, E.; Sebestyen, E.; Rotta, L.; Gentile, F.; Vaira, V.; Lanzuolo, C.; Ferrari, F.
10.1101/2024.03.05.583467 — genomics — Posted on 2024-03-07
4024 Adaptive admixture at ACKR1 (the Duffy locus) may have shaped Plasmodium vivax prevalence in Oman
Haffener, P. E.; Al-Riyami, A. Z.; Al-Zadjali, S.; Busby, G. B. J.; Al Mahdhuri, S.; Al-Rawahi, M.; Al Hosni, S.; Al Marhoobi, A.; Al Sheriyani, A.; Leffler, E. M.
10.1101/2024.03.06.583766 — genetics — Posted on 2024-03-07
4026 Fine-scale oceanographic processes shape marine biodiversity patterns in the Galapagos Islands
Holman, L. E.; Pazmino, D. A.; Gopalakrishnan, S.; Forryan, A.; Hearn, A. R.; Naveira-Garabato, A. C.; Rius, M.
10.1101/2024.03.06.583537 — ecology — Posted on 2024-03-07
4028 EDC-3 and EDC-4 Regulate Embryonic mRNA Clearance and Biomolecular Condensate Specialization
Vidya, E.; Jami-Alahmadi, Y.; Mayank, A. K.; Rizwan, J.; Xu, J. M. S.; Cheng, T.; Leventis, R.; Sonenberg, N.; Wohlschlegel, J.; Vera, M.; Duchaine, T.
10.1101/2024.03.04.583404 — molecular biology — Posted on 2024-03-07
4030 FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling
Khan, M. S. H.; Kim, S. Q.; Ross, R. C.; Corpodean, F.; Span, R. A.; Albarado, D. A.; Fernandez-Kim, S. O.; Clarke, B.; Berthoud, H.-R.; Münzberg, H.; Albaugh, V. L.; Soto, P.; Morrison, C. D.
10.1101/2024.03.05.583399 — neuroscience — Posted on 2024-03-07
4032 Zinc Alpha-2-Glycoprotein (ZAG/AZGP1) secreted by triple-negative breast cancer promotes tumor microenvironment fibrosis.
Verma, S.; Giagnocavo, S. D.; Curtin, M. C.; Arumugam, M.; Osburn-Staker, S. M.; Wang, G.; Atkinson, A.; Nix, D. A.; Lum, D. H.; Cox, J. E.; Hilgendorf, K. I.
10.1101/2024.03.04.583349 — cancer biology — Posted on 2024-03-07
4034 Long-read sequencing and genome assembly of natural history collection samples and challenging specimens
Bein, B.; Chrysostomakis, I.; Arantes, L.; Brown, T.; Gerheim, C.; Schell, T.; Schneider, C.; Leushkin, E.; Chen, Z.; Sigwart, J.; Gonzalez, V.; Wong, L.; Santos, F.; Blom, M.; Mayer, F.; Mazzoni, C.; Boehne, A.; Winkler, S.; Greve, C.; Hiller, M.
10.1101/2024.03.04.583385 — genomics — Posted on 2024-03-07
4036 Impacts of yeast Tma20/MCTS1, Tma22/DENR and Tma64/eIF2D on translation reinitiation and ribosome recycling
Jendruchov, K.; Gaikwad, S.; Poncova, K.; Gunisova, S.; Valasek, L. S.; Hinnebusch, A. G.
10.1101/2024.03.06.583729 — genetics — Posted on 2024-03-07
4037 RPA and Rad27 limit templated and inverted insertions at DNA breaks
Ira, G.; Yu, Y.; Chen, K.; Wang, X.; Fox, J.; Hastings, P. J.; Yu, Y.; Li, Q.
10.1101/2024.03.07.583931 — genetics — Posted on 2024-03-07
4038 Proteogenomic analysis reveals adaptive strategies to alleviate the consequences of aneuploidy in cancer
Boekenkamp, J.-E.; Keuper, K.; Redel, S.; Barthel, K.; Johnson, L.; Wieland, A.; Raschle, M.; Storchova, Z.
10.1101/2024.03.05.583460 — genetics — Posted on 2024-03-07
4039 Antisense transcription can induce expression memory via stable promoter repression
Mutzel, V.; Schwämmle, T.; Oeverdieck, S.; Librenjak, L.; Boesen, B.; Bothe, M.; Gjaltema, R. A.; Dunkel, I.; Noviello, G.; Schulz, E. G.
10.1101/2024.03.06.583761 — genetics — Posted on 2024-03-07
4040 Light as an "ecological trap". A synanthropic incipient speciation taken up by the gecko
Fulgione, D.; Maselli, V.; Avallone, B.; Rivieccio, E.; Mondanaro, A.; Giurato, G.; Buglione, M.
10.1101/2024.03.05.583480 — evolutionary biology — Posted on 2024-03-07
4041 PRDM9 drives the location and rapid evolution of recombination hotspots in salmonids
Raynaud, M.; Sanna, P.; Joseph, J.; Clement, J.; Imai, Y.; Lareyre, J.-J.; Laurent, A.; Galtier, N.; Baudat, F.; Duret, L.; Gagnaire, P.-A.; de Massy, B.
10.1101/2024.03.06.583651 — evolutionary biology — Posted on 2024-03-07
4042 Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for Leptospira serology
Mummah, R. O.; Gomez, A. C. R.; Guglielmino, A. H.; Borremans, B.; Galloway, R. L.; Prager, K. C.; Lloyd-Smith, J. O.
10.1101/2024.03.05.583452 — ecology — Posted on 2024-03-07
4045 Nucleotidyltransferase toxin MenT targets and extends the aminoacyl acceptor ends of serine tRNAs in vivo to control Mycobacterium tuberculosis growth
XU, X.; BARRIOT, R.; VOISIN, B.; ARROWSMITH, T. J.; USHER, B.; GUTIERREZ, C.; HAN, X.; REDDER, P.; BLOWER, T. R.; NEYROLLES, O.; GENEVAUX, P.
10.1101/2024.03.07.583660 — microbiology — Posted on 2024-03-07
4047 A history of repeated antibiotic usage leads to microbiota-dependent mucus defects
Krigul, K. L.; Feeney, R. H.; Wongkuna, S.; Aasmets, O.; Holmberg, S. M.; Andreson, R.; Puertolas-Balint, F.; Pantiukh, K.; Sootak, L.; Org, T.; Tenson, T.; Org, E.; Schroeder, B. O.
10.1101/2024.03.07.583875 — microbiology — Posted on 2024-03-07
4049 A Novel Humanized Mouse Model for HIV and Tuberculosis Co-infection Studies
Yi, G.; Bohorquez, J. A.; Adduri, S.; Ansari, D.; John, S.; Florence, J.; Adejare, O.; Singh, G.; Konduru, N. V.; Jagannath, C.
10.1101/2024.03.05.583545 — immunology — Posted on 2024-03-07
4050 An ethologically relevant paradigm to assess visual contrast sensitivity in rodents
Calanni, J. S.; Aranda, M. L.; Dieguez, H. H.; Dorfman, D.; Schmidt, T. M.; Rosenstein, R. E.
10.1101/2024.03.05.583559 — neuroscience — Posted on 2024-03-07
4053 DR5 disulfide bonding as a sensor and effector of protein folding stress
Law, M. E.; Dulloo, Z. M.; Eggleston, S. R.; Takacs, G. P.; Alexandrow, G. M.; Wang, M.; Su, H.; Forsyth, B. A.; Chiang, C.-W.; Sharma, A.; Kanumuri, S. R. R.; Guryanova, O. A.; Harrison, J. K.; Tirosh, B.; Castellano, R. K.; Law, B. K.
10.1101/2024.03.04.583390 — cancer biology — Posted on 2024-03-07
4054 Evolutionary trajectories of IDH-mutant astrocytoma identify molecular grading markers related to cell cycling
Vallentgoed, W. R.; Hoogstrate, Y.; van Garderen, K. A.; van Hijfte, L.; van Dijk, E.; Kouwenhoven, M. C.; Niers, J. M.; Draaisma, K.; Martin, I.; de Leng, W. W.; Tesileanu, C. M. S.; de Heer, I.; Diepeveen, M.; Lavrova, A.; Eijk, P. P.; Buehler, M.; Wick, W.; Clement, P. M.; Sanson, M.; Franceschi, E.; Gorlia, T.; Golfinopoulos, V.; Weller, M.; Weiss, T.; Robe, P. A.; Kros, J. M.; Smits, M.; van de Wiel, M.; Ylstra, B.; Verhaak, R. G.; van den Bent, M. J.; Westerman, B.; Wesseling, P.; French, P. J.
10.1101/2024.03.05.583306 — cancer biology — Posted on 2024-03-07
4055 Iterative in silico identification of P-glycoprotein inhibitors
McCormick, L. A.; McCormick, J. W.; Park, C.; Wise, J. G.; Vogel, P. D.
10.1101/2024.03.05.583428 — cancer biology — Posted on 2024-03-07
4056 Probing recombinant AAV capsid integrity and genome release under thermal stress by single-molecule interferometric scattering microscopy
Ebberink, E. H. T. M.; Ruisinger, A.; Nuebel, M.; Meyer-Berg, H.; Ferreira, I. R. S.; Thomann, M.; Heck, A. J. R.
10.1101/2024.03.07.583968 — biophysics — Posted on 2024-03-07
4057 Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response
Huang, H.-C.; Lobo, V.; Schon, K.; Nowak, I.; Westholm, J. O.; Fernandez, C.; Patel, A. A.; Wiel, C.; Sayin, V. I.; Anastasakis, D. G.; Angeletti, D.; Sarshad, A.
10.1101/2024.03.07.583365 — biochemistry — Posted on 2024-03-07
4061 A male-essential microRNA is key for avian sex chromosome dosage compensation
Fallahshahroudi, A.; Rodriguez-Montes, L.; Yousefi Taemeh, S.; Trost, N.; Tellez, M.; Ballantyne, M.; Idoko-Akoh, A.; Taylor, L.; Sherman, A.; Sorato, E.; Johnsson, M.; Cardoso Moreira, M.; McGrew, M.; Kaessmann, H.
10.1101/2024.03.06.581755 — evolutionary biology — Posted on 2024-03-07
4065 Uncovering the transcriptional molecular dynamics of shelf life extension and system acquired resistance induction to Fusarium pallidoroseum in melon fruits by the use of pulsed-light
Arge, L. W. P.; Morais, G. L.; Carvalho, J. B.; Zocolo, G. J.; Oster, A. H.; Vasconcelos, A. T. R. d.; Diniz, L. E. C.; Silva, E. d. O.; Bordallo, P. d. N.
10.1101/2024.03.05.583617 — molecular biology — Posted on 2024-03-07
4066 CemR atypical response regulator impacts energy conversion in Campylobacteria
Noszka, M.; Strzalka, A.; Muraszko, J.; Hofreuter, D.; Abele, M.; Ludwig, C.; Stingl, K.; Pawlik, A. M.
10.1101/2024.03.07.583886 — molecular biology — Posted on 2024-03-07
4070 Deciphering lentiviral Vpr/x determinants required for HUSH and SAMHD1 antagonism highlights the molecular plasticity of these evolutionary conflicts
Larrous, P.; Garnier, C.; Martin, M. M.; Morel, M.; Zarrouk, K.; Maesen, S.; Matkovic, R.; Cimarelli, A.; Etienne, L.; Margottin-Goguet, F.
10.1101/2024.03.07.583867 — microbiology — Posted on 2024-03-07
4072 Experimental challenge of Chinook salmon with Tenacibaculum maritimum and Tenacibaculum dicentrarchi fulfils Kochs postulates
Kumanan, K.; Carson, J.; Hunter, R. B. J.; Rolton, A.; von Ammon, U.; Bandaranayake, C.; Angelucci, C.; Morrison, R. N.; Walker, S. P.; Symonds, J. E.; Hutson, K. S.
10.1101/2024.03.06.583827 — microbiology — Posted on 2024-03-07
4074 Development of antibacterial drug plus bacteriophage combination assays
Attwood, M. E.; Griffin, P.; NOEL, A. R.; Josephs, T.; Adler, K.; Cloke, M. R.; MacGowan, A. P.
10.1101/2024.03.07.583836 — microbiology — Posted on 2024-03-07
4075 Protocatechuic acid induces endogenous oxidative stress in CR-hvKP by regulating the EMP-PPP pathway
Zhong, Y.; Cheng, Y.; Xing, S.; Zhang, X.; Luo, S.; Shi, X.; He, Y.; Liu, H.; Yang, M.; Si, H.-B.
10.1101/2024.03.06.583678 — microbiology — Posted on 2024-03-07
4076 The segmented flavivirus Alongshan virus reduces mitochondrial mass via degrading STAT2 to suppress innate immune response
Zhao, Y.; Sui, L.; Pan, M.; Jin, F.; Huang, Y.; Fang, S.; Wang, M.; Che, L.; Xu, W.; Liu, N.; Liu, N.; Gao, H.; Hou, Z.; Du, F.; Wei, Z.; Zhao, J.; Zhang, K.; Zhao, Y.; Wang, Z.-D.; Liu, Q.
10.1101/2024.03.06.583679 — microbiology — Posted on 2024-03-07
4077 Long distance avian migrants fail to bring 2.3.4.4b HPAI H5N1 into Australia for a second year in a row
Wille, M.; Atkinson, R.; Barr, I. G.; Burgoyne, C.; Bond, A. L.; Boyle, D.; Christie, M.; Dewar, M.; Douglas, T.; Fitzwater, T.; Hassell, C.; Jessop, R.; Klaassen, H.; Lavers, J. L.; Leung, K. K.- S.; Ringma, J.; Sutherland, D. R.; Klaassen, M.
10.1101/2024.03.06.583767 — microbiology — Posted on 2024-03-07
4078 Dynamic Adaptation in Extant Porins Facilitates Antibiotic Tolerance in Energetic Escherichia coli
Mukhopadhyay, S.; Bishayi, R.; Shaji, A.; Lee, A. H.; Gupta, R.; Mohajeri, M.; Katiyar, A.; McKee, B.; Schmitz, I. R.; Shin, R.; Lele, T. P.; Lele, P. P.
10.1101/2024.03.07.583920 — microbiology — Posted on 2024-03-07
4080 Role of Hepatocyte RIPK1 in Maintaining Liver Homeostasis during Metabolic Challenges
Zhang, W.; Zhang, D.; Yi, Y.; Tao, L.; Zhao, X.; Shao, Q.; Li, P.; Zhang, J.; Zhang, H.; Chen, Y.; Weng, D.
10.1101/2024.03.04.583302 — immunology — Posted on 2024-03-07
4081 DeepPrep: An accelerated, scalable, and robust pipeline for neuroimaging preprocessing empowered by deep learning
Ren, J.; An, N.; Lin, C.; Zhang, Y.; Sun, Z.; Zhang, W.; Li, S.; Guo, N.; Cui, W.; Hu, Q.; Wang, W.; Wu, X.; Wang, Y.; Jiang, T.; Satterthwaite, T. D.; Wang, D.; Liu, H.
10.1101/2024.03.06.581108 — neuroscience — Posted on 2024-03-07
4082 Comprehensive mapping of sensory and sympathetic innervation of the developing kidney
N'Guetta, P.-E. Y.; McLarnon, S. R.; Tassou, A.; Geron, M.; Shirvan, S.; Hill, R. Z.; Scherrer, G.; O'Brien, L. L.
10.1101/2023.11.15.567276 — developmental biology — Posted on 2024-03-07
4083 Defining the EM-signature of successful cell-transfection
Pemberton, J. G.; Tenkova, T.; Felgner, P. L.; Zimmerberg, J.; Balla, T.; Heuser, J. E.
10.1101/2024.03.07.583927 — cell biology — Posted on 2024-03-07
4085 Single-cell analysis identifies distinct macrophage phenotypes associated with pro-disease and pro-resolving functions in the endometriotic niche
Henlon, Y.; Panir, K.; McIntyre, I.; Hogg, C.; Dhami, P.; Cuff, A. O.; Senior, A.; Moolchandani-Adwani, N.; Courtois, E. T.; Horne, A. W.; Rosser, M.; Ott, S.; Greaves, E.
10.1101/2024.03.07.583861 — immunology — Posted on 2024-03-07
4091 Thymic epithelial organoids mediate T cell development
Hubscher, T.; Lorenzo-Martin, F.; Barthlott, T.; Tillard, L.; Langer, J.; Rouse, P.; Blackburn, C.; Hollander, G. C.; Lutolf, M.
10.1101/2024.03.05.583513 — developmental biology — Posted on 2024-03-07
4093 Nano-scale viscometry reveals an inherent mucus defect in cystic fibrosis
Ponomarchuk, O.; Boudreault, F.; Gryczynski, I.; Dzyuba, S. V.; Fudala, R.; Gryczynski, Z.; Hanrahan, J. W.; Grygorczyk, R.
10.1101/2024.03.06.583796 — cell biology — Posted on 2024-03-07
4094 Nature AND Nurture: Enabling formate-dependent growth in Methanosarcina acetivorans
Bao, J.; Somvanshi, T.; Tian, Y.; Laird, M.; Garcia, P. S.; Schoene, C.; Rother, M.; Borrel, G.; Scheller, S.
10.1101/2024.01.08.574737 — microbiology — Posted on 2024-03-07
4098 Large- and Small-Animal Studies of Safety, Pharmacokinetics (PK), and Biodistribution of Inflammasome-Targeting Nanoligomer in the Brain and Other Target Organs
Risen, S.; Kusick, B.; Sharma, S.; Gilberto, V.; Brindley, S.; Aguilar, M.; Brown, J.; McGrath, S.; Chatterjee, A.; Moreno, J.; Nagpal, P.
10.1101/2024.02.07.579323 — pharmacology and toxicology — Posted on 2024-03-07
4100 Computational design of soluble functional analogues of integral membrane proteins
Goverde, C. A.; Pacesa, M.; Goldbach, N.; Balbi, P. E.; Dornfeld, L. J.; Georgeon, S.; Rosset, S.; Kapoor, S.; Choudhury, J.; Dauparas, J.; Shellhaas, C.; Kozlov, S.; Baker, D.; Ovchinnikov, S.; Vecchio, A. J.; Correia, B.
10.1101/2023.05.09.540044 — bioinformatics — Posted on 2024-03-07
4101 Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies
Nazeen, S.; Wang, X.; Zielinski, D.; Lam, I.; Hallacli, E.; Xu, P.; Ethier, E.; Strom, R.; Zanella, C. A.; Nithianandam, V.; Ritter, D.; Henderson, A.; Saurat, N.; Afroz, J.; Nutter-Upham, A.; Benyamini, H.; Copty, J.; Ravishankar, S.; Morrow, A.; Mitchel, J.; Neavin, D.; Gupta, R.; Farbehi, N.; Grundman, J.; Myers, R. H.; Scherzer, C. R.; Trojanowski, J. Q.; Van Deerlin, V. M.; Cooper, A. A.; Lee, E. B.; Erlich, Y.; Lindquist, S.; Peng, J.; Geschwind, D. H.; Powell, J.; Studer, L.; Feany, M. B.; Sunyaev, S. R.; Khurana, V.
10.1101/2024.03.03.583145 — genomics — Posted on 2024-03-07
4102 In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma
Liu, S. J.; Pak, J.; Zou, C.; Casey-Clyde, T.; Borah, A.; Wu, D.; Seo, K.; O'Loughlin, T.; Lim, D.; Ozawa, T.; Berger, M.; Weiss, W.; Raleigh, D. R.; Gilbert, L. A.
10.1101/2023.09.01.555831 — genomics — Posted on 2024-03-07
4104 CLEM-Reg: An automated point cloud based registration algorithm for correlative light and volume electron microscopy
Krentzel, D.; Elphick, M.; Domart, M.-C.; Peddie, C. J.; Laine, R. F.; Henriques, R.; Collinson, L. M.; Jones, M. L.
10.1101/2023.05.11.540445 — cell biology — Posted on 2024-03-07
4107 Unraveling and quantifying "Candidatus Saccharibacteria": in silico and experimental evaluation of V3-V4 16S rRNA metagenomics and qPCR protocols
Papaleo, S.; Nodari, R.; Sterzi, L.; D'Auria, E.; Cattaneo, C.; Bettoni, G.; Bonaiti, C.; Pagliarini, E.; Zuccotti, G. V.; Panelli, S.; Comandatore, F.
10.1101/2024.03.06.583507 — microbiology — Posted on 2024-03-07
4108 Protein design for evaluating vaccines against future viral variation
Youssef, N.; Gurev, S.; Ghantous, F.; Brock, K. P.; Jaimes, J. A.; Thadani, N. N.; Dauphin, A.; Sherman, A. C.; Yurkovetskiy, L.; Soto, D.; Estanboulieh, R.; Kotzen, B.; Notin, P.; Kollasch, A. W.; Cohen, A. A.; Dross, S. E.; Erasmus, J.; Fuller, D. H.; Bjorkman, P. J.; Lemieux, J. E.; Luban, J.; Seaman, M. S.; Marks, D.
10.1101/2023.10.08.561389 — immunology — Posted on 2024-03-07
4112 Endogenous Intracellular Metabolites Allosterically Modulate GPCR-Gα Interface
Mohanty, S. K.; Mittal, A.; Gaur, A.; Namra, ; Duari, S.; Solanki, S.; Sharma, A. K.; Arora, S.; Kumar, S.; Gautam, V.; Dixit, N. K.; Subramanian, K.; Ghosh, T. S.; Sengupta, D.; Sharma, D.; Gupta, S. K.; Murugan, N. A.; Ahuja, G.
10.1101/2023.02.14.528587 — bioinformatics — Posted on 2024-03-07
4113 A short 3'UTR motif regulates gene expression in bilaterians
Eufrasio, A.; Azevedo, J.; Machado, J.; Ferreira, A.; Moutinho, A.; Henriques, F.; Jesus, A.; Tavares, J.; Pereira-Castro, I.; Teixeira, J.; Araujo, M.; Pinto, P. A.; Bessa, J.; Moreira, A.
10.1101/2023.11.15.567165 — molecular biology — Posted on 2024-03-07
4114 Entrainment Echoes in the Cerebellum
Zoefel, B.; Abbasi, O.; Gross, J.; Kotz, S. A.
10.1101/2024.03.06.583255 — neuroscience — Posted on 2024-03-07
4115 A new archaeal virus that suppresses the transcription of host immunity genes
Turgeman-Grott, I.; Golan, N.; Neri, U.; Naki, D.; Altman-Price, N.; Eizenshtein, K.; Choudhary, D. K.; Levy, R.; Himani, H.; Shalev, Y.; Reshef, L.; Gophna, U.
10.1101/2024.02.12.579488 — microbiology — Posted on 2024-03-07
4118 Thermal Contrast Enhancement Predicts Paradoxical Heat Sensation
Mitchell, A. G.; Fischer Ehmsen, J.; Basinska, M.; Courtin, A. S.; Bohme, R. A.; Sardeto Deolindo, C.; Allen, M. G.; Sandberg, K.; Fardo, F.
10.1101/2023.08.23.554435 — neuroscience — Posted on 2024-03-07
4127 Subtypes of brain change in aging and their associations with cognition and Alzheimer's disease biomarkers
Capogna, E.; Sorensen, O.; Watne, L. O.; Roe, J.; Stromstad, M.; Idland, A. V.; Halaas, N. B.; Blennow, K.; Zetterberg, H.; Walhovd, K. B.; the Alzheimer's Disease Neuroimaging Initiative, ; the Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing, ; Fjell, A. M.; Vidal-Pineiro, D.
10.1101/2024.03.04.583291 — neuroscience — Posted on 2024-03-07
4128 Comparing the limbic-frontal connectome across the primate order: conservation of connections and implications for translational neuroscience
Folloni, D.; Roumazeilles, L.; Bryant, K. L.; Manger, P. R.; Bertelsen, M. F.; Khrapitchev, A. A.; Rudebeck, P. H.; Mars, R. B.
10.1101/2024.03.06.583735 — neuroscience — Posted on 2024-03-07
4129 Endocannabinoid biomarkers of vulnerability to the development of trauma-induced generalized fear responses
Szente, L.; Balla, G. Y.; Varga, Z. K.; Toth, B.; Biro, L.; Balogh, Z.; Hill, M. N.; Toth, M.; Mikics, E.; Aliczki, M.
10.1101/2024.03.06.583339 — neuroscience — Posted on 2024-03-07
4131 Developmental trajectory of cortical somatostatin interneuron function
Wang, A.; Ferguson, K. A.; Gupta, J.; Higley, M. J.; Cardin, J. A.
10.1101/2024.03.05.583539 — neuroscience — Posted on 2024-03-07
4135 MYT1L deficiency impairs excitatory neuron trajectory during cortical development
Yen, A.; Chen, X.; Skinner, D. D.; Leti, F.; Crosby, M.; Hoisington-Lopez, J.; Wu, Y.; Chen, J.; Mitra, R. D.; Dougherty, J. D.
10.1101/2024.03.06.583632 — neuroscience — Posted on 2024-03-07
4136 Up-regulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain
Agostini, F.; Pereyra, L.; Dale, J.; Yambire, K. F.; Maglioni, S.; Schiavi, A.; Ventura, N.; Milosevic, I.; Raimundo, N.
10.1101/2024.03.06.583589 — biochemistry — Posted on 2024-03-07
4141 Novel multi-omics deconfounding variational autoencoders can obtain meaningful disease subtyping
Li, Z.; Katz, S.; Saccenti, E.; Fardo, D.; Claes, P.; Martins dos Santos, V. A. P.; Van Steen, K.; Roshchupkin, G. V.
10.1101/2024.02.05.578873 — genomics — Posted on 2024-03-07
4142 Knotted artifacts in predicted 3D RNA structures
Gren, B. A.; Antczak, M.; Zok, T.; Sulkowska, J. I.; Szachniuk, M.
10.1101/2024.03.04.583268 — bioinformatics — Posted on 2024-03-07
4146 Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity
Carmi, Y.; Farhat-Younis, L.; Na, M.; Zarfin, A.; Santana-Magal, N.; Richter, A.; Khateeb, A.; Gutwillig, A.; Rasoulouniriana, D.; Gleiberman, A.; Beck, L.; Giger, T.; Ashkenazi, A.; Barzel, A.; Rider, P.
10.1101/2023.09.30.560338 — immunology — Posted on 2024-03-07
4148 Noradrenergic locus coeruleus activity functionally partitions NREM sleep to gatekeep the NREM-REM sleep cycle
Osorio-Forero, A.; Foustoukos, G.; Cardis, R.; Cherrad, N.; Devenoges, C.; Fernandez, L. M.; Luthi, A.
10.1101/2023.05.20.541586 — neuroscience — Posted on 2024-03-07
4150 In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma
Liu, S. J.; Pak, J.; Zou, C.; Casey-Clyde, T.; Borah, A.; Wu, D.; Seo, K.; O'Loughlin, T.; Lim, D.; Ozawa, T.; Berger, M.; Weiss, W.; Raleigh, D. R.; Gilbert, L. A.
10.1101/2023.09.01.555831 — genomics — Posted on 2024-03-07
4152 Dual-color MINFLUX: Kinesin-1 takes Chasse-Inchworm steps
Scheiderer, L.; Wirth, J. O.; Tarnawski, M.; Hell, S. W.
10.1101/2024.03.05.583551 — biophysics — Posted on 2024-03-06
4154 The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics
Mc Cartney, A. M.; Formenti, G.; Mouton, A.; De Panis, D.; Marins, L. S.; Leitao, H. G.; Diedericks, G.; Kirangwa, J.; Morselli, M.; Salces, J.; Escudero, N.; Iannucci, A.; Natali, C.; Svardal, H.; Fernandez, R.; De Pooter, T.; Joris, G.; Strazisar, M.; Wood, J.; Herron, K. E.; Seehausen, O.; Watts, P. C.; Shaw, F.; Davey, R. P.; Minotto, A.; Fernandez Gonzalez, J. M.; Bohne, A.; Alegria, C.; Alioto, T.; Alves, P. C.; Amorim, I. R.; Aury, J.-M.; Backstrom, N.; Baldrian, P.; Ballarin, L.; Baltrunaite, L.; Barta, E.; BedHom, B.; Belser, C.; Bergsten, J.; Bertrand, L.; Bilandija, H.; Binzer-Panch
10.1101/2023.09.25.559365 — genomics — Posted on 2024-03-06
4155 Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies
Nazeen, S.; Wang, X.; Zielinski, D.; Lam, I.; Hallacli, E.; Xu, P.; Ethier, E.; Strom, R.; Zanella, C. A.; Nithianandam, V.; Ritter, D.; Henderson, A.; Saurat, N.; Afroz, J.; Nutter-Upham, A.; Benyamini, H.; Copty, J.; Ravishankar, S.; Morrow, A.; Mitchel, J.; Neavin, D.; Gupta, R.; Farbehi, N.; Grundman, J.; Myers, R. H.; Scherzer, C. R.; Trojanowski, J. Q.; Van Deerlin, V. M.; Cooper, A. A.; Lee, E. B.; Erlich, Y.; Lindquist, S.; Peng, J.; Geschwind, D. H.; Powell, J.; Studer, L.; Feany, M. B.; Sunyaev, S. R.; Khurana, V.
10.1101/2024.03.03.583145 — genomics — Posted on 2024-03-06
4158 Astrocytes in the mouse suprachiasmatic nuclei respond directly to glucocorticoids feedback
Haendler, K.; Sreenivasan, V. K. A.; Pilorz, V.; Bringas, J. O.; Castanondo, L. E.; Bengoa-Vergniory, N.; Oster, H.; Spielmann, M.; Astiz, M.
10.1101/2024.03.04.583323 — developmental biology — Posted on 2024-03-06
4160 Reflection confocal microscopy for quantitative assessment of airway surface liquid dysregulation and pharmacological rescue in cystic fibrosis under near-physiological conditions
Agircan, A. S.; Lampe, M.; Scheuermann, H.; Albrecht, T.; Graeber, S. Y.; Balazs, A.; Baumann, I.; Block, S.; Pepperkok, R.; Mall, M. A.; Duerr, J.
10.1101/2024.03.05.583496 — cell biology — Posted on 2024-03-06
4161 DERIVATION OF ELEPHANT INDUCED PLURIPOTENT STEM CELLS
Appleton, E. M.; Hong, K.; Rodriguez, C.; Tanaka, Y.; Ashkenazy-Titelman, A.; Bhide, K.; Rasmussen-Ivey, C.; Ambriz-Pena, X.; Korover, N.; Bai, H.; Quieroz, A.; Nelson, J.; Rathod, G.; Knox, G.; Morgan, M.; Malviya, N.; Zhang, K.; Kehler, J.; Kowalczyk, A.; Bow, A.; McLendon, B.; Cantarel, B. L.; James, M.; Mason, C. E.; Gray, C.; Koehler, K.; Pearson, V.; Lamm, B.; Church, G.; Hysolli, E.
10.1101/2024.03.05.583606 — cell biology — Posted on 2024-03-06
4162 Matrix viscoelasticity controls epithelial cell mechanobiology through dimensionality
Ciccone, G.; Oliva, M. A. G.; Versaevel, M.; Cantini, M.; Vassalli, M.; Salmeron-Sanchez, M.; Gabriele, S.
10.1101/2024.03.05.583526 — biophysics — Posted on 2024-03-06
4163 Liebenberg syndrome severity arises from variations in Pitx1 locus topology and ectopically transcribing cells
Bompadre, O.; Rouco, R.; Darbellay, F.; Rauseo, A.; Guerard-Millet, F.; Gentile, C.; Kmita, M.; Andrey, G.
10.1101/2024.03.04.582675 — developmental biology — Posted on 2024-03-06
4164 Centriole structural integrity defects are a crucial feature of Hydrolethalus Syndrome
Curinha, A.; Huang, Z.; Anglen, T.; Strong, M. A.; Gliech, C. R.; Jewett, C. E.; Friskes, A.; Holland, A. J.
10.1101/2024.03.06.583733 — cell biology — Posted on 2024-03-06
4167 Vitrification by high pressure freezing of a wide variety of sample using the HPM Live μ
Kodera, C.; Bret, Y.; Eyraud, F.; Heiligenstein, J.; Belle, M.; Heiligenstein, X.
10.1101/2024.03.06.583669 — cell biology — Posted on 2024-03-06
4168 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus
Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.
10.1101/2023.08.22.554078 — molecular biology — Posted on 2024-03-06
4169 Under the radar: differential responses of bed bugs to an entomopathogen, environmental bacteria, and a human pathogen
Walt, H. K.; Bronzato-Badial, A.; Maedo, S. E.; Hinton, J. A.; King, J. G.; Pietri, J.; Hoffmann, F. G.
10.1101/2024.02.28.582586 — molecular biology — Posted on 2024-03-06
4172 A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation.
Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Thompson, C.; Kural, C.; Shepherd, D. P.; Presse, S. P.
10.1101/2023.12.07.570701 — biophysics — Posted on 2024-03-06
4174 The development of brain pericytes requires expression of the transcription factor nkx3.1 in intermediate precursors
Ahuja, S.; Adjekukor, C.; Li, Q.; Kocha, K. M.; Rosin, N.; Labit, E.; Sinha, S.; Narang, A.; Long, Q.; Biernaskie, J.; Huang, P.; Childs, S. J.
10.1101/2023.06.21.545941 — developmental biology — Posted on 2024-03-06
4175 Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction
Gao, X.; Zhang, B.; Liu, P.; Yuwen, M.; Liu, Z.; Tan, R.; Wang, B.; Liu, K.; Yang, Z.; Ba, J.; Bai, X.; Shama, S.; Tang, C.; Liu, L.; Zhu, C.; Wang, T.; Li, S.; Kang, J.
10.1101/2024.01.06.574490 — cell biology — Posted on 2024-03-06
4177 Cell class-specific electric field entrainment of neural activity
Lee, S. Y.; Kozalakis, K.; Baftizadeh, F.; Campagnola, L.; Jarsky, T.; Koch, C.; Anastassiou, C. A.
10.1101/2023.02.14.528526 — neuroscience — Posted on 2024-03-06
4181 Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4
Ravala, S. K.; Adame-Garcia, S. R.; Li, S.; Chen, C.-L.; Cianfrocco, M. A.; Gutkind, J. S.; Cash, J. N.; Tesmer, J. J. G.
10.1101/2023.09.15.557836 — biochemistry — Posted on 2024-03-06
4185 An isogenic E. coli population gives rise to multiple persister phenotypes
Rahman, K. M. T.; Amaratunga, R.; Singh, A.; Hossain, T.; Butzin, N. C.
10.1101/2023.12.09.570944 — microbiology — Posted on 2024-03-06
4186 High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen.
Ogongo, P.; Tran, A.; Marzan, F.; Gingrich, D.; Krone, M.; Aweeka, F.; Lindestam Arlehamn, C. S.; Martin, J. N.; Deeks, S.; Hunt, P. W.; Ernst, J. D.
10.1101/2023.01.06.523027 — immunology — Posted on 2024-03-06
4188 SleepEEGpy: a Python-based software 'wrapper' package to organize preprocessing, analysis, and visualization of sleep EEG data
Belonosov, G.; Falach, R.; Schmidig, F. J.; Aderka, M.; Zhelezniakov, V.; Shani-Hershkovich, R.; Bar, E.; Nir, Y.
10.1101/2023.12.17.572046 — neuroscience — Posted on 2024-03-06
4190 Sequence modeling and design from molecular to genome scale with Evo
Nguyen, E.; Poli, M.; Durrant, M. G.; Thomas, A. W.; Kang, B.; Sullivan, J.; Ng, M. Y.; Lewis, A.; Patel, A.; Lou, A.; Ermon, S.; Baccus, S. A.; Hernandez-Boussard, T.; Re, C.; Hsu, P. D.; Hie, B. L.
10.1101/2024.02.27.582234 — synthetic biology — Posted on 2024-03-06
4191 Evaluating polarizable biomembrane simulations against experiments
Kav, B.; Antila, H. S.; Dixit, S.; Miettinen, M. S.; Madsen, J. J.; Ollila, O. H. S.
10.1101/2023.12.01.569661 — biophysics — Posted on 2024-03-06
4192 Structure-based discovery of positive allosteric modulators for the calcium sensing receptor
Liu, F.; Wu, C.-G.; Tu, C.-L.; Glenn, I.; Meyerowitz, J.; Kaplan, A. L.; Lyu, J.; Cheng, Z.; Tarkhanova, O. O.; Moroz, Y. S.; Irwin, J. J.; Chang, W.; Shoichet, B. K.; Skiniotis, G.
10.1101/2023.12.27.573448 — biophysics — Posted on 2024-03-06
4194 Temporally resolved early BMP-driven transcriptional cascade during human amnion specification
Sekulovski, N.; Wettstein, J. C.; Carleton, A. E.; Juga, L. N.; Taniguchi, L. E.; Ma, X.; Rao, S.; Kropp Schmidt, J.; Golos, T.; Lin, C.-W.; Taniguchi, K.
10.1101/2023.06.19.545574 — developmental biology — Posted on 2024-03-06
4195 An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity
Kucharski, T.; Vlasac, I.; Higgs, M.; Christensen, B.; Bechstedt, S.; Compton, D. A.
10.1101/2023.08.06.552174 — cell biology — Posted on 2024-03-06
4197 Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification
Zhang, C.; Wu, B.; Wu, Y. F.; di Ciano-Oliveira, C.; Soria-Bretones, I.; Pham, N.-A.; Elia, A. J.; Chari, R.; Lam, W. L.; Bray, M. R.; Mak, T. W.; Tsao, M.-S.; Cescon, D. W.; Thu, K. L.
10.1101/2024.01.09.574105 — cancer biology — Posted on 2024-03-06
4199 Molecular mechanism of α-latrotoxin action
Klink, B. U.; Alavizargar, A.; Subramaniam, K. K.; Chen, M.; Heuer, A.; Gatsogiannis, C.
10.1101/2024.03.06.583760 — biochemistry — Posted on 2024-03-06
4206 CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair
Zondervan, R. L.; Capobianco, C. A.; Jenkins, D. C.; Reicha, J. D.; Fredrick, L. M.; Lam, C.; Isenberg, J. S.; Ahn, J.; Marcucio, R. S.; Hankenson, K. D.
10.1101/2024.03.06.583756 — molecular biology — Posted on 2024-03-06
4210 Effect of phage variation on Shiga toxin 2 (Stx2) production and the virulence of Stx-producing Escherichia coli
Nakamura, K.; Nakayama-Imaohji, H.; Emmanuel, M.; Taniguchi, I.; Gotoh, Y.; Isobe, J.; Kimata, K.; Igawa, Y.; Kitahashi, T.; Takahashi, Y.; Nomoto, R.; Iwabuchi, K.; Morimoto, Y.; Iyoda, S.; Kuwahara, T.; Hayashi, T.
10.1101/2024.03.06.583675 — microbiology — Posted on 2024-03-06
4211 The transition from a non-westernized to westernized gut microbiome in Indian-Immigrants and Indo-Canadians is associated with dietary acculturation
D'Aloisio, L. D.; Haskey, N.; Abulizi, N.; Karimianghadim, R.; Liu, C.; Chowdary, S.; Siva, L.; Vasudevan, S.; Shetty, V.; Bhaumik, U.; Ballal, M.; Howlader, D. R.; Pakpour, S.; Ghosh, S.; Barnett, J.; Gibson, D. L.
10.1101/2024.03.04.582285 — microbiology — Posted on 2024-03-06
4214 Unraveling and quantifying "Candidatus Saccharibacteria": in silico and experimental evaluation of V3-V4 16S rRNA metagenomics and qPCR protocols
Papaleo, S.; Nodari, R.; Sterzi, L.; D'Auria, E. C.; Cattaneo, C.; Bettoni, G.; Bonaiti, C.; Pagliarini, E.; Zuccotti, G. V.; Panelli, S.; Comandatore, F.
10.1101/2024.03.06.583507 — microbiology — Posted on 2024-03-06
4215 The microbiome of the lichen Lobaria pulmonaria varies according to climate in Europe
Bogale, A. T.; Braun, M.; Bernhardt, J.; Zuehlke, D.; Schiefelbein, U.; Bog, M.; Scheidegger, C.; Zengerer, V.; Becher, D.; Grube, M.; Riedel, K.; Bengtsson, M. M.
10.1101/2024.03.06.583579 — microbiology — Posted on 2024-03-06
4216 Erg251 has complex and pleiotropic effects on azole susceptibility, filamentation, and stress response phenotypes
Zhou, X.; Hilk, A.; Solis, N. V.; Hogan, B. M.; Bierbaum, T. A.; Filler, S. G.; Burrack, L. S.; Selmecki, A.
10.1101/2024.03.06.583770 — microbiology — Posted on 2024-03-06
4217 Targeting G9a translational mechanism of SARS-CoV-2 pathogenesis for multifaceted therapeutics of COVID-19 and its sequalae
Muneer, A.; Xie, L.; Xie, X.; Zhang, F.; Wrobel, J.; Yan, X.; Yu, X.; Wang, C.; Gheorghe, C.; Wu, P.; Song, J.; Ming, G.-L.; Jin, J.; Song, H.; Shi, P.-Y.; Chen, X.
10.1101/2024.03.04.583415 — immunology — Posted on 2024-03-06
4218 Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection
Ogongo, P.; Wassie, L.; Tran, A.; Columbus, D.; Sharling, L.; Ouma, G.; Ouma, S. G.; Bobosha, K.; Lindestam Arlehamn, C. S.; Gandhi, N. R.; Auld, S. C.; Rengarajan, J.; Day, C. L.; Altman, J. D.; Blumberg, H.; Ernst, J. D.
10.1101/2024.03.05.583634 — immunology — Posted on 2024-03-06
4219 Early cytokine-driven adaptation of survival pathways in lymphoid cells during targeted therapies
Luo, M.-X.; Tan, T.; Trussart, M.; Poch, A.; Nguyen, M. H. T.; Speed, T. P.; Hicks, D. G.; Bandala-Sanchez, E.; Peng, H.; Chappaz, S.; Slade, C.; Utzschneider, D. T.; Strasser, A.; Thijssen, R.; Ritchie, M. E.; Tam, C. S.; Lindeman, G.; Huang, D. C.; Lew, T. E.; Anderson, M. A.; Roberts, A. W.; Teh, C. E.; Gray, D. H.
10.1101/2024.03.04.583422 — cancer biology — Posted on 2024-03-06
4221 Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants
Khalid, M. M.; Chen, I.; Soveg, F. S.; Taha, T. Y.; Tabata, T.; Suryawanshi, R.; Syed, A. M.; Ciling, A.; McCavitt-Malvido, M.; Schulze-Gahmen, U.; Hayashi, J.; Kim, I.-J.; Fong, S. W.; Batra, J.; Kumar, G. R.; Laurent, R.; NG, L. F.; Krogan, N. J.; Doudna, J. A.; Verdin, E.; Ott, M.
10.1101/2024.03.05.583578 — microbiology — Posted on 2024-03-06
4223 Deciphering Oxygen Distribution and Hypoxia Profiles in the Tumor Microenvironment: A Data-Driven Mechanistic Modeling Approach
Kumar, P.; Lacroix, M.; Dupre, P.; Arslan, J.; Fenou, L.; Orsetti, B.; Le Cam, L.; Racoceanu, D.; Radulescu, O.
10.1101/2024.03.04.583326 — cancer biology — Posted on 2024-03-06
4225 Immunomagneto-activated hepatocyte-specific tissue vesicle profiling reveals message diversification from regenerating liver
Ying, S.; Cao, Y.; Liu, L.; Zhou, Z.-K.; Luo, X.-Y.; Li, C.-H.; Chen, S.-Y.; Lei, X.; Xing, S.-J.; Shi, K.; Qiu, J.-Y.; Zhang, K.; Li, Y.-Y.; Zheng, C.-X.; Jin, F.; Sui, B.; Jin, Y.
10.1101/2024.03.03.583167 — cell biology — Posted on 2024-03-06
4227 Damage sensing through TLR9 Promotes Viral Clearance and Recovery During Influenza Infection
Kim, J.; Yuan, Y.; Agaronyan, K.; Zhao, A.; Wang, V. D.; Gupta, G.; Essayas, H.; Kaminski, A.; McGovern, J.; Yu, S.; Woo, S.; Lee, C. J.; Saleh, T.; Hu, B.; Sun, Y.; Ishikawa, G.; Bain, W.; Evankovich, J.; Herzog, E.; Dela Cruz, C. S.; Ryu, C.; Sharma, L.
10.1101/2024.03.04.583378 — immunology — Posted on 2024-03-06
4230 Hyaluronidase impacts exposures of long-acting injectable paliperidone palmitate in rodent models
Pertinez, H.; Kaushik, A.; Curley, P.; Arshad, U.; El-Khateeb, E.; Li, S.-Y.; Tasneen, R.; Sharp, J.; Kijak, E.; Herriott, J.; Neary, M.; Noe, M.; Flexner, C.; Nuermberger, E.; Owen, A.; Ammerman, N. C.
10.1101/2024.03.03.583160 — pharmacology and toxicology — Posted on 2024-03-06
4232 LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice
Volpatti, L. R.; Norton de Matos, S.; Borjas, G.; Reda, J.; Watkins, E. A.; Zhou, Z.; Nguyen, M.; Solanki, A.; Fang, Y.; Hubbell, J. A.
10.1101/2024.03.04.582839 — bioengineering — Posted on 2024-03-06
4233 Mitochondrial dynamics regulate cell size in the developing cochlea
O'Sullivan, J. D.; Terry, S.; Scott, C. A.; Bullen, A.; Jagger, D. J.; Mann, Z. F.
10.1101/2024.03.04.583298 — developmental biology — Posted on 2024-03-06
4235 STRIPAK controls cell-cell communication by promoting cytoneme biogenesis through the membrane-sculpting function of Slik.
Rambaud, B.; Joseph, M.; Tsai, F.-C.; De Jamblinne, C. V.; Del Guidice, E.; Sabelli, R.; Bassereau, P.; Hipfner, D. R.; Carreno, S.
10.1101/2024.03.04.583182 — cell biology — Posted on 2024-03-06
4236 Deep learning methods to forecasting human embryo development in time-lapse videos
Sharma, A.; Dorobantiu, A.; Ali, S.; Iliceto, M.; Stensen, M. H.; Delbarre, E.; Riegler, M. A.; Hammer, H. L.
10.1101/2024.03.04.583269 — cell biology — Posted on 2024-03-06
4237 The sodium-proton exchangers sNHE and NHE1 control plasma membrane hyperpolarization in mouse sperm.
Novero, A. G.; Rodriguez, P. T.; de la Vega Beltran, J. L.; Schiavi-Ehrenhaus, L. J.; Luque, G. M.; Carruba, M.; Stival, C.; Gentile, I.; Ritagliati, C.; Santi, C. M.; Nishigaki, T.; Krapf, D.; Buffone, M. G.; Darszon, A.; Trevino, C. L.; Krapf, D.
10.1101/2024.03.04.583310 — cell biology — Posted on 2024-03-06
4238 Reconstitution of the uterine immune milieu after transplantation
Strunz, B.; Ivarsson, M.; Sun, D.; Ziegenhain, C.; Crona Guterstam, Y.; Solders, M.; Bjorklund, A.; Marquardt, N.; Kaipe, H.; Floter-Radestad, A.; Brusell-Gidlof, S.; Brannstrom, M.; Bjorkstrom, N. K.
10.1101/2024.03.04.583277 — immunology — Posted on 2024-03-06
4241 Loss of Esr1 Does Not Affect Hearing and Balance
Simms, S. S.; Milani, M.; Kim, M.-J.; Husain, R. M.; Infante, L. P.; Cooke, P. S.; Someya, S.
10.1101/2024.03.03.583163 — neuroscience — Posted on 2024-03-06
4242 Medial prefrontal dopamine dynamics reflect allocation of selective attention
Melugin, P. R.; Nolan, S. O.; Kandov, E.; Ferrara, C. F.; Farahbakhsh, Z. Z.; Siciliano, C. A.
10.1101/2024.03.04.583245 — neuroscience — Posted on 2024-03-06
4243 Application of Cancer Cell Line Encyclopedia for Measuring Correlation Between Transcriptomics and Proteomics as a Guide for System-level Insights
Williams, B.; Perry, D.; Aspesi, P.; Parker, J.; Johnson, T.; Su, W.; Tabacman, E.; Delisle, K.; Avishan, K.; Myer, V.; Mapa, F.; Hinterberg, M.; Williams, A.; Jennings, L.; Janjic, N.; Loureiro, J.
10.1101/2024.03.03.583123 — systems biology — Posted on 2024-03-06
4244 PFKP regulates AXL-MET oncogenic and metabolic pathways in lung cancer
Sun, Y.; Zhao, H.; Feng, H.; Liu, Y.; Li, Y.; Chen, S.; Zhou, Z.; Du, Y.; Zeng, X.; Ren, H.; Su, W.; Mei, Q.; Chen, G.
10.1101/2024.03.03.583230 — cancer biology — Posted on 2024-03-06
4245 Spatial Transcriptomics of Spinal Ependymoma in NF2-related Schwannomatosis
Burket, N. J.; Wang, J.; Gao, H. J.; Bell, R.; Zhang, C.; Liu, Y.; Clapp, W.; Tailor, J. K.
10.1101/2024.03.03.583240 — cancer biology — Posted on 2024-03-06
4250 Knotted artifacts in predicted 3D RNA structures
Gren, B. A.; Antczak, M.; Zok, P.; Sulkowska, J. I.; Szachniuk, M.
10.1101/2024.03.04.583268 — bioinformatics — Posted on 2024-03-06
4251 GenoTriplo: A SNP genotype calling method for triploids
Roche, J.; Besson, M.; Allal, F.; Haffray, P.; Patrice, P.; Vandeputte, M.; Phocas, F.
10.1101/2024.03.03.583188 — bioinformatics — Posted on 2024-03-06
4252 Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors
Suazo, K.; Mishra, V.; Maity, S.; Auger, S.; Justyna, K.; Petre, A.; Ottoboni, L.; Ongaro, J.; Corti, S.; Lotti, F.; Przedborski, S.; Distefano, M. D.
10.1101/2024.03.03.583211 — biochemistry — Posted on 2024-03-06
4258 A transient brain endothelial translatome response to endotoxin is associated with mild cognitive changes post-shock in young mice
Lu, S.; Portela, I. D. J.; Martino, N.; Ramos, R. B.; Salinero, A.; Smith, R.; Zuloaga, K. L.; Adam, A. P.
10.1101/2024.03.03.583191 — neuroscience — Posted on 2024-03-06
4260 PCSK9 deficiency promotes the development of peripheral neuropathy
Jaafar, A. K.; Paulo-Ramos, A.; Rastoldo, G.; Veeren, B.; Planesse, C.; Bringart, M.; Rondeau, P.; Lambert, G.; Meilhac, O.; Bourane, S.
10.1101/2024.03.03.583154 — neuroscience — Posted on 2024-03-06
4262 A unique subset of pericystic endothelium associates with aberrant microvascular remodelling and impaired blood perfusion early in polycystic kidney disease
Jafree, D. J.; Perera, C.; Ball, M.; Tolomeo, D.; Pomeranz, G.; Wilson, L.; Davis, B.; Mason, W. J.; Funk, E. M.; Kolatsi-Joannou, M.; Polschi, R.; Malik, S.; Stewart, B. J.; Price, K. L.; Mitchell, H.; Motallebzadeh, R.; Muto, Y.; Lees, R.; Needham, S. R.; Moulding, D.; Chandler, J. C.; Walsh, C. L.; Woolf, A. S.; Winyard, P. J.; Scambler, P. J.; Hagerling, R.; Clatworthy, M. R.; Humphreys, B.; Lythgoe, M. F.; Walker-Samuel, S.; Long, D. A.
10.1101/2024.03.03.583132 — pathology — Posted on 2024-03-06
4265 Prevalent fast evolution of genes involved in heterochromatin functions
Lin, L.; Huang, Y.; McIntyre, J.; Chang, C.-H.; Colmenares, S. S.; Lee, G. Y. C.
10.1101/2024.03.03.583199 — evolutionary biology — Posted on 2024-03-06
4266 Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity
Tejero, J.; Hesterberg, R.; Drapela, S.; Ilter, D.; Raizada, D.; Lazure, F.; Kashfi, H.; Liu, M.; Fernandez-Garcia, J.; Fendt, S.-M.; Asara, J.; Cleveland, J.; Gomes, A. P.
10.1101/2024.03.03.583124 — immunology — Posted on 2024-03-06
4267 Maternal cannabis use alters excitatory inputs to corticostriatal efferent neurons in rat offspring
Ginder, D. E.; Weimar, H. V.; Lindberg, J. E. M.; Fisher, Z. D. G.; Lim, M. M.; Peters, J. H.; McLaughlin, R. J.
10.1101/2024.03.03.583210 — neuroscience — Posted on 2024-03-06
4270 Opioid receptor expressing neurons of the central amygdala gate behavioral effects of ketamine in mice
Pomrenze, M. B.; Vaillancourt, S.; Llorach, P.; Rijsketic, D. R.; Casey, A. B.; Gregory, N.; Salgado, J. S.; Malenka, R. C.; Heifets, B. D.
10.1101/2024.03.03.583196 — neuroscience — Posted on 2024-03-06
4281 Spiking GABAergic OPC tumor cells prolong survival in IDH1 mutant glioma
Curry, R. N.; Ma, Q.; McDonald, M. F.; Ko, Y.; Srivastava, S.; Chin, P.-S.; He, P.; Lozzi, B.; Aiba, I.; Meyer, J.; Jing, J.; Wang, S.; Harmanci, A. O.; Athukuri, P.; Noebels, J.; Arenkiel, B.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2024.03.02.583026 — cancer biology — Posted on 2024-03-06
4282 Development of a Bipyrimidineamide based α-Helix Mimetic Lead Compound for efficient Targeting of MDM2 in Triple-Negative Breast Cancer
On, J. L.; Woloschin, V.; Gier, F.; Tu, J.-W.; Bhatia, S.; Lenz, T.; Stühler, K.; Niederacher, D.; Neubauer, H.; Fehm, T.; Kurz, T.; Esser, K.
10.1101/2024.03.02.582899 — cancer biology — Posted on 2024-03-06
4288 Leveraging Single-Cell Sequencing to Classify and Characterize Tumor Subgroups in Bulk RNA-Sequencing Data
Shetty, A.; Wang, S.; Khan, A. B.; English, C. W.; Nouri, S. H.; Magill, S. T.; Raleigh, D. R.; Klisch, T. J.; Harmanci, A. O.; Patel, A. J.; Serin Harmanci, A.
10.1101/2024.03.02.583114 — bioinformatics — Posted on 2024-03-06
4289 Gcoupler: An AI-enhanced tool unveiled Endogenous Intracellular Allosteric Modulators of Evolutionary Conserved GPCR-Gα Interface
Mohanty, S. K.; Mittal, A.; Gaur, A.; Namra, ; Duari, S.; Solanki, S.; Sharma, A. K.; Arora, S.; Kumar, S.; Gautam, V.; Dixit, N. K.; Subramanian, K.; Ghosh, T. S.; Sengupta, D.; Sharma, D.; Gupta, S. K.; Murugan, N. A.; Ahuja, G.
10.1101/2023.02.14.528587 — bioinformatics — Posted on 2024-03-06
4290 EpicTope: narrating protein sequence features to identify non-disruptive epitope tagging sites
Zinski, J.; Chung, H.; Joshi, P.; Warrick, F.; Berg, B. D.; Glova, G.; McGrail, M. A.; Balciunas, D.; Friedberg, I.; Mullins, M. C.
10.1101/2024.03.03.583232 — developmental biology — Posted on 2024-03-06
4293 A worldwide ENIGMA study on epilepsy-related gray and white matter compromise across the adult lifespan
Chen, J.; Ngo, A.; Rodriguez-Cruces, R.; Royer, J.; Caligiuri, M. E.; Gambardella, A.; Concha, L.; Keller, S. S.; Cendes, F.; Yasuda, C. L.; Alvim, M. K. M.; Bonilha, L.; Gleichgerrcht, E.; Focke, N. K.; Kreilkamp, B.; Domin, M.; von Podewils, F.; Langner, S.; Rummel, C.; Wiest, R.; Martin, P.; Kotikalapudi, R.; Bender, B.; O'Brien, T. J.; Sinclair, B.; Vivash, L.; Kwan, P.; Desmond, P. M.; Lui, E.; Duma, G. M.; Bonanni, P.; Ballerini, A.; Vaudano, A. E.; Meletti, S.; Tondelli, M.; Alhusaini, S.; Doherty, C. P.; Cavalleri, G. L.; Delanty, N.; Kälviäinen, R.; Jackson, G.; Kowalczyk, M.; Masca
10.1101/2024.03.02.583073 — neuroscience — Posted on 2024-03-06
4294 Temporal interference electrical neurostimulation yields fMRI BOLD activation in humans
Modak, P.; Fine, J.; Colon, B.; Need, E.; Hulvershorn, L.; Finn, P.; Brown, J.
10.1101/2024.03.02.583125 — neuroscience — Posted on 2024-03-06
4295 Olfactory bulb stimulation mitigates Alzheimer-like disease progression
Raoufy, M. R.; Salimi, M.; Shahsavar, P.; Dehghan, S.; Javan, M.; Mirnajafi Zadeh, J.; Nazari, M.
10.1101/2024.03.03.583116 — neuroscience — Posted on 2024-03-06
4299 Haplotype-resolved karyotype construction from Hi-C data using refLinker
Brunette, G. J.; Tourdot, R. W.; Wangsa, D.; Pellman, D.; Zhang, C.-Z.
10.1101/2024.03.02.583108 — genomics — Posted on 2024-03-06
4303 Aurora B controls microtubule stability to regulate abscission dynamics in stem cells
Kodba, S.; Oztop, A.; van Berkum, E.; Iwanski, M. K.; Nijenhuis, W.; Kapitein, L. C.; Chaigne, A.
10.1101/2024.03.06.583686 — cell biology — Posted on 2024-03-06
4304 Tofacitinib uptake by patient-derived intestinal organoids predicts individual clinical responsiveness
Jang, K. K.; Ercelen, D.; Cen Feng, J. Y. C.; Gurunathan, S.; Zhou, C.; Korman, A.; Newell, L.; Hudesman, D.; Jones, D. R.; Loke, P.; Axelrad, J. E.; Cadwell, K.
10.1101/2024.03.02.583137 — cell biology — Posted on 2024-03-06
4305 The CCR4/CCL17 axis drives intestinal acute Graft versus Host disease after allogeneic bone marrow transplantation
Schlaweck, S.; Klesse, M.; Schanz, O.; Jorch, S. K.; Kristiansen, G.; Toma, M.; Flores, C.; Becker-Gotot, J.; Kurts, C.; Brossart, P.; Wolf, D.; Heine, A.
10.1101/2024.03.02.583093 — immunology — Posted on 2024-03-06
4306 Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38
Shin, O. S.; Monticelli, S. R.; Hjorth, C. K.; Hornet, V.; Doyle, M.; Abelson, D.; Kuehne, A. I.; Wang, A.; Bakken, R. R.; Mishra, A. K.; Middlecamp, M.; Champney, E.; Stuart, L.; Maurer, D. P.; Li, J.; Berrigan, J. L.; Balinandi, S.; Lutwama, J. J.; Lobel, L.; Zeitlin, L.; Walker, L. M.; Dye, J. M.; Chandran, K.; Herbert, A. S.; Pauli, N. T.; McLellan, J. S.
10.1101/2024.03.02.583110 — immunology — Posted on 2024-03-06
4307 Giardia intestinalis reshapes mucosal immunity toward a Type 2 response that attenuates inflammatory bowel-like diseases
Sardinha-Silva, A.; Gazzinelli-Guimaraes, P. H.; Ajakaye, O. G.; Ferreira, T. R.; Alves-Ferreira, E.; Tjhin, E. T.; Gregg, B.; Fink, M. Y.; Coelho, C. H.; Singer, S. M.; Grigg, M. E.
10.1101/2024.03.02.583119 — immunology — Posted on 2024-03-06
4308 Automated identification and quantification of stereotypical movements from video recordings of children with ASD
Barami, T.; Manelis-Baram, L.; Kaiser, H.; Ilan, M.; Slobodkin, A.; Hadashi, O.; Hadad, D.; Waissengreen, D.; Nitzan, T.; Menashe, I.; Michaelovsky, A.; Begin, M.; Zachor, D.; Sadaka, Y.; Koler, J.; Zagdon, D.; Meiri, G.; Azencot, O.; Sharf, A.; Dinstein, I.
10.1101/2024.03.02.582828 — neuroscience — Posted on 2024-03-06
4309 Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe
Donkels, C.; Huber, S.; Demerath, T.; Scheiwe, C.; Schah, M. J.; Heers, M.; Urbach, H.; Schulze-Bonhage, A.; Prinz, M.; Haeussler, U.; Vlachos, A.; Beck, J.; Nakagawa, J. M.; Haas, C. A.
10.1101/2024.03.02.582894 — neuroscience — Posted on 2024-03-06
4311 Resistance to PSEN1-selective γ-secretase inhibitors in T-cell acute lymphoblastic leukemia
Vandersmissen, C.; Demeyer, S.; Jacobs, K.; Boogaerts, L.; Fernandez, S. G.; Segers, H.; Chavez-Gutierrez, L.; Cools, J.
10.1101/2024.03.01.582944 — cancer biology — Posted on 2024-03-06
4313 HER2 Prognostic Significance and Therapeutic Implications in Gastric Cardia Adenocarcinoma: Insights from Multi-Omics Profiling
Wang, L.; Xing, p.; Zhao, X.; Song, X.; Wei, M.; Lei, L.; Xu, R.; Wang, R.; Ma, L.; You, D.; Chen, P.; Xie, M.; Zhao, M.; Zhang, H.; Lv, H.; Li, A.; Wang, X.; Zhou, F.; Gao, S.; Chen, X.
10.1101/2024.03.02.583089 — cancer biology — Posted on 2024-03-06
4317 Investigating the effects of protons versus x-rays on radiation-induced lymphopenia after brain irradiation
Coupey, J.; Pham, T. N.; Toutain, J.; Ivanova, V.; HUE, E.; Helaine, C.; Ismail, A.; Saulnier, R.; Simonin, G.; Rousseau, M.; Moignier, C.; Thariat, J.; Valable, S.
10.1101/2024.03.02.583088 — cell biology — Posted on 2024-03-06
4318 Misspellings or miscellings- non-verifiable cell lines in cancer research publications
Oste, D. J.; Pathmendra, P.; Richardson, R. A. K.; Johnson, G.; Ao, Y.; Arya, M. D.; Enochs, N. R.; Hussein, M.; Kang, J.; Lee, A.; Danon, J. J.; Cabanac, G.; Labbe, C.; Capes Davis, A.; Stoeger, T.; Byrne, J. A.
10.1101/2024.02.29.582220 — cancer biology — Posted on 2024-03-06
4319 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences
Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.
10.1101/2024.03.05.583455 — microbiology — Posted on 2024-03-06
4321 Altered X-chromosome inactivation predisposes to autoimmunity
Huret, C.; Ferraye, L.; David, A.; Mohamed, M.; Valentin, N.; Charlotte, F.; Savignac, M.; Goodhardt, M.; Guery, J.-C.; Rougeulle, C.; Morey, C.
10.1101/2023.04.20.537662 — immunology — Posted on 2024-03-06
4322 Glutamatergic Supramammillary Nucleus Neurons Respond to Threatening Stressors and Promote Active Coping
Escobedo, A.; Holloway, S.-A.; Votoupal, M.; Cone, A. L.; Skelton, H. E.; Legaria, A.; Ndiokho, I.; Floyd, T.; Kravitz, A. V.; Bruchas, M. R.; Norris, A. J.
10.1101/2022.09.22.507167 — neuroscience — Posted on 2024-03-06
4327 Individual genotype but not phenotype predicts river migration success in Atlantic salmon
Moccetti, P.; Bolland, J. D.; Adams, C. E.; Rodger, J. R.; Honkanen, H. M.; Newton, M.; Lothian, A. J.; Nunn, A. D.; Joyce, D. A.
10.1101/2023.08.15.553252 — evolutionary biology — Posted on 2024-03-06
4329 Ilamycin E and ilamycin F are dual inhibitors of ClpX and ClpC1 in mycobacteria
Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.
10.1101/2024.02.24.581832 — microbiology — Posted on 2024-03-06
4330 Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp.
Wong, O.; Mezcord, V.; Lopez, C.; Traglia, G. M.; Pasteran, F.; Tuttobene, M. R.; Corso, A.; Tolmasky, M.; Bonomo, R. A.; Ramirez, M. S.
10.1101/2024.03.04.583376 — microbiology — Posted on 2024-03-06
4334 Macrophage mediated mesoscale brain mechanical homeostasis mechanically imaged via optical tweezers and Brillouin microscopy in vivo
So, W. Y.; Johnson, B.; Gordon, P. B.; Bishop, K. S.; Gong, H.; Burr, H. A.; Staunton, J. R.; Handler, C.; Sood, R.; Scarcelli, G.; Tanner, K.
10.1101/2023.12.27.573380 — biophysics — Posted on 2024-03-06
4336 Multicore-fiber microendoscopy for functional cellular in-organ imaging
Dancker, T. A.; Elhawy, M. I.; Rittershauss, R.; Tian, Q.; Schwarz, Y.; Hoffmann, M. D. A.; Carlein, C.; Wyatt, A.; Wahl, V.; Speyerer, D.; Kandah, A.; Boehm, U.; Prates Roma, L.; Bruns, D.; Lipp, P.; Krasteva-Christ, G.; Lauterbach, M. A.
10.1101/2024.03.02.583077 — bioengineering — Posted on 2024-03-06
4338 Intermittent stimulation of the basal forebrain improves working memory in aged nonhuman primates.
Wang, Z.; Pennington, K. R.; Debs, L.; Chung, S.; Bava, J. M.; Garin, C.; Vale, F. L.; Bick, S. K.; Englot, D. J.; Terry, A. V.; Constantinidis, C.; Blake, D. T.
10.1101/2024.03.01.582925 — neuroscience — Posted on 2024-03-06
4340 Large-scale single-cell profiling of stem cells uncovers redundant regulators of shoot development and yield trait variation
Xu, X.; Passalacqua, M.; Rice, B.; Demesa-Arevalo, E.; Kojima, M.; Takebayashi, Y.; Harris, B.; Sakakibara, H.; Gallavotti, A.; Gillis, J.; Jackson, D.
10.1101/2024.03.04.583414 — plant biology — Posted on 2024-03-06
4343 Engineering a wolf spider A-family toxin towards increased antimicrobial activity but low toxicity
Dersch, L.; Stahlhut, A.; Eichberg, J.; Paas, A.; Hardes, K.; Vilcinskas, A.; Lueddecke, T.
10.1101/2024.03.04.583312 — bioengineering — Posted on 2024-03-06
4344 High-Throughput Phenotyping of Seed Quality Traits Using Imaging and Deep Learning in Dry Pea
Morales, M.; Worral, H.; Piche, L.; Atanda, S. A.; Dariva, F.; Ramos, C.; Hoang, K.; Yan, C.; Flores, P.; Bandillo, N.
10.1101/2024.03.05.583564 — plant biology — Posted on 2024-03-06
4345 Cis inhibition of co-expressed DIPs and Dprs shapes neural development
Morano, N. C.; Lopez, D. S.; Meltzer, H.; Sergeeva, A. P.; Katsamba, P. S.; Gupta, H. P.; Becker, J. E.; Bornstein, B.; Cosmanescu, F.; Schuldiner, O.; Mann, R. S.; Honig, B.; Shapiro, L.
10.1101/2024.03.04.583391 — biochemistry — Posted on 2024-03-06
4347 A novel sulfatase for acesulfame degradation in wastewater treatment plants as evidenced from Shinella strains
Ding, C.; Rohwerder, T.; Liu, Y.; Bonatelli, M. L.; Von Postel, T.; Kleinsteuber, S.; Adrian, L.
10.1101/2024.03.04.583314 — genomics — Posted on 2024-03-06
4350 A Spatial Multi-Modal Dissection of Host-Microbiome Interactions within the Colitis Tissue Microenvironment
Zhu, B.; Bai, Y.; Yeo, Y. Y.; Lu, X.; Rovira-Clave, X.; Chen, H.; Yeung, J.; Gerber, G. K.; Angelo, M.; Shalek, A. K.; Nolan, G. P.; Jiang, S.
10.1101/2024.03.04.583400 — immunology — Posted on 2024-03-06
4351 Biolearn, an open-source library for biomarkers of aging
Ying, K.; Paulson, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.
10.1101/2023.12.02.569722 — bioinformatics — Posted on 2024-03-06
4357 Multi-Scale Protein Language Model for Unified Molecular Modeling
Zheng, K.; Long, S.; Lu, T.; Yang, J.; Dai, X.; Zhang, M.; Nie, Z.; Ma, W.-Y.; Zhou, H.
10.1101/2024.03.04.583284 — bioinformatics — Posted on 2024-03-06
4358 High-fidelity annotated genome of the polyploid and quarantine root-knot nematode, Meloidogyne enterolobii
Poullet, M.; Gopal, H.; Rancurel, C.; Sallaberry, M.; Lopez-Roques, C.; Lledo, J.; Kiewnick, S.; Danchin, E. G. J.
10.1101/2024.03.01.582926 — genomics — Posted on 2024-03-06
4359 First report of astroviruses in Tanzanian bats
Joffrin, L.; Iliopoulou, E.; Falzon, M.; Sabuni, C.; Kirkpatrick, L.; De Bruyn, L.
10.1101/2024.03.05.581362 — molecular biology — Posted on 2024-03-06
4360 Transmission-blocking activity of artesunate, chloroquine and methylene blue on Plasmodium vivax gametocytes.
Chaumeau, V.; Wasisakun, P.; Watson, J. A.; Oo, T.; Aryalamloed, S.; Sue, M. P.; Htoo, G. N.; Tha, N. M.; Archusuksan, L.; Sawasdichai, S.; Gornsawun, G.; Mehra, S.; White, N. J.; Nosten, F.
10.1101/2024.02.18.580875 — microbiology — Posted on 2024-03-06
4362 Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes
Alempic, J.-M.; Bisio, H.; Villalta, A.; Santini, S.; Lartigue, A.; Schmitt, A.; Bugnot, C.; Notaro, A.; BELMUDES, L.; Adrait, A.; Poirot, O.; Ptchelkine, D.; De Castro, C.; Coute, Y.; Abergel, C.
10.1101/2023.04.28.538727 — microbiology — Posted on 2024-03-06
4365 Widespread neural and autonomic system synchrony across the brain-body axis
Bolt, T. S.; Wang, S.; Nomi, J. S.; Setton, R.; Gold, B.; Frederick, B.; Chen, J. J.; Picchioni, D.; Spreng, R. N.; Keilholz, S.; Uddin, L.; Chang, C.
10.1101/2023.01.19.524818 — neuroscience — Posted on 2024-03-06
4367 Predicting the Beat Bin - Beta Oscillations Predict the Envelope Sharpness in a Rhythmic Sequence
Leske, S.; Endestad, T.; Volehaugen, V.; Foldal, M. D.; Blenkmann, A. O.; Solbakk, A.-K.; Danielsen, A.
10.1101/2023.07.21.550020 — neuroscience — Posted on 2024-03-06
4369 SleepEEGpy: a Python-based software 'wrapper' package to organize preprocessing, analysis, and visualization of sleep EEG data
Belonosov, G.; Falach, R.; Schmidig, F. J.; Aderka, M.; Zhelezniakov, V.; Shani-Hershkovich, R.; Bar, E.; Nir, Y.
10.1101/2023.12.17.572046 — neuroscience — Posted on 2024-03-06
4371 Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns
Kamei, K.-i. F.; Kobayashi-Kirschvink, K. J.; Nozoe, T.; Nakaoka, H.; Umetani, M.; Wakamoto, Y.
10.1101/2023.05.09.539921 — systems biology — Posted on 2024-03-06
4378 Reconstitution of cytolinker-mediated crosstalk between actin and vimentin
Isturiz Petitjean, I.; Tran, Q. D.; Goutou, A.; Kabir, Z.; Wiche, G.; Leduc, C.; Koenderink, G. H.
10.1101/2023.10.27.564417 — biochemistry — Posted on 2024-03-06
4381 Scaling Properties for Artificial Neural Network Models of a Small Nervous System
Simeon, Q.; Venancio, L. R.; SKUHERSKY, M.; Nayebi, A.; Boyden, E. S.; Yang, G.
10.1101/2024.02.13.580186 — neuroscience — Posted on 2024-03-06
4383 Particulate Contamination of Human Placenta: Plastic and Non-Plastic
Zurub, R. W.; Bainbridge, S. A.; Rahman, L.; Halappanavar, S.; Wade, M.
10.1101/2024.03.01.583005 — physiology — Posted on 2024-03-06
4385 Chrom-pro: A User-Friendly Toolkit for De-novo Chromosome Assembly and Genomic Analysis
Song, W.; Ye, T.; Liu, S.; Shen, D.; Du, Y.; Yang, Y.; Lu, Y.; Jin, H.; huo, y.; Piao, W.; Jin, H.
10.1101/2024.03.02.583079 — bioinformatics — Posted on 2024-03-05
4388 Telomere-to-telomere genome assembly of a male goat reveals novel variants associated with cashmere traits
Wu, H.; Luo, L.-Y.; Zhang, Y.-H.; Zhang, C.-Y.; Huang, J.-H.; Mo, D.-X.; Zhao, L.-M.; Wang, Z.-X.; Wang, Y.-C.; EEr, H.-H.; Bai, W.-L.; Han, D.; Dou, X.-T.; Ren, Y.-L.; Dingkao, R.; Chen, H.-L.; Ye, Y.; Du, H.-D.; Zhao, Z.-Q.; Wang, X.-J.; Jia, S.-G.; Liu, Z.; Li, M.-H.
10.1101/2024.03.03.582909 — genomics — Posted on 2024-03-05
4391 Evolved and plastic gene expression in adaptation to a novel niche
Steward, R. A.; Ortega Gimenez, J.; Choudhary, S.; Yi, S.; Aken, O. V.; Runemark, A.
10.1101/2024.03.02.583104 — evolutionary biology — Posted on 2024-03-05
4394 First report of astroviruses in Tanzanian bats
Joffrin, L.; Iliopoulou, E.; Falzon, M.; Sabuni, C.; Kirkpatrick, L.; De Bruyn, L.
10.1101/2024.03.05.581362 — molecular biology — Posted on 2024-03-05
4395 Development of Broad-spectrum β-cyclodextrins-Based Nanomaterials Against Influenza Viruses
Zwygart, A. C.-A.; Medaglia, C.; Zhu, Y.; Tarbet, E. B.; Westover, J. B.; Fage, C.; Le Roy, D.; Roger, T.; Constant, S.; Huang, S.; Stellacci, F.; Silva, P. J.; Tapparel, C.
10.1101/2024.03.05.583334 — microbiology — Posted on 2024-03-05
4399 An immune signature of postoperative cognitive decline in elderly patients
Verdonk, F.; Cambriel, A.; Hedou, J.; Ganio, E.; Bellan, G.; Gaudilliere, D.; Einhaus, J.; Sabayev, M.; Stelzer, I. A.; Feyaerts, D.; Bonham, A. T.; Ando, K.; Choisy, B.; Drover, D.; Heifets, B.; Chretien, F.; Aghaeepour, N.; Angst, M. S.; Molliex, S.; Sharshar, T.; Gaillard, R.; Gaudilliere, B.
10.1101/2024.03.02.582845 — neuroscience — Posted on 2024-03-05
4402 TALEN-mediated intron editing of HSPCs enables transgene expression restricted to the myeloid lineage
Seclen, E.; Jang, J. C.; Lawal, A. O.; Pulicani, S.; Boyne, A.; Tkach, D.; Juillerat, A.; Duchateau, P.; Valton, J.
10.1101/2024.03.05.583596 — bioengineering — Posted on 2024-03-05
4403 A complete mitochondrial genome of a Roman-era Plasmodium falciparum
Llanos-Lizcano, A.; Haemmerle, M.; Sperduri, A.; Sawyer, S.; Zagorc, B.; Ozdogan, K. T.; Cheronet, O.; Guellil, M.; Kuhlwilm, M.; Pinhasi, R.; Gelabert, P.
10.1101/2024.03.05.583465 — genomics — Posted on 2024-03-05
4404 Chromatin packing domains persist after RAD21 depletion in 3D.
Li, W. S.; Carter, L. M.; Almassalha, L. M.; Pujadas-Liwag, E. M.; Kuo, T.; MacQuarrie, K. L.; Carignano, M. A. M.; Dravid, V. P.; Kanemaki, M.; Szleifer, I. G.; Backman, V.
10.1101/2024.03.02.582972 — genomics — Posted on 2024-03-05
4406 Nucleolar accumulation of APE1 through condensates is mediated by rRNA forming G-quadruplex structures
Dall Agnese, G.; Hannett, N. M.; Overholt, K. J.; Platt, J. M.; Henninger, J. E.; Marcos-Vidal, A.; Antoniali, G. E.; Tell, G.
10.1101/2024.03.04.583447 — molecular biology — Posted on 2024-03-05
4407 FMNL2 regulates actin for ER and mitochondria distribution in oocyte meiosis
Pan, M.-H.; Pan, Z.-N.; Sun, M.-H.; Li, X.-H.; Ju, J.-Q.; Luo, S.-M.; Ou, X.-H.; Sun, S.
10.1101/2023.10.05.561058 — developmental biology — Posted on 2024-03-05
4412 Reconciling the importance of minerals for propagation of antibiotic resistance genes in the environment
Hendiani, S.; Carbajo, C.; Hansen, M. F.; Agbaje, O.; Arellano, P.; Verma, T.; Mandic Mulec, I.; Burmoelle, M.; Sand, K. K.
10.1101/2024.03.04.583397 — microbiology — Posted on 2024-03-05
4413 Prophages block cell surface receptors to ensure survival of their viral progeny
Taylor, V. L.; Shah, M.; Patel, P. H.; Yusuf, A.; Burk, C. M.; Gitai, Z.; Davidson, A. R.; Koch, M. D.; Maxwell, K. L.
10.1101/2024.03.05.583538 — microbiology — Posted on 2024-03-05
4414 Spatial patterns of Hyalomma marginatum-borne pathogens in the Occitanie region (France), a focus on the intriguing dynamics of Rickettsia aeschlimannii
KUKLA, C. J.; Bernard, C.; Bru, D.; Galon, C.; Giupponi, C.; Huber, K.; Jourdan-Pineau, H.; Malandrin, L.; Rakotoarivony, I.; Riggi, C.; Vial, L.; Moutailler, S.; Pollet, T.
10.1101/2024.03.05.583534 — microbiology — Posted on 2024-03-05
4415 Yeast-based production platform for potent and stable heavy chain-only antibodies
Lonigro, C.; Eeckhaut, H.; Symakani, R. A.; Roose, K.; Schepens, B.; Sedeyn, K.; De Smet, A.-S.; Zavala Marchan, J. C.; Vanhaverbeke, P.; Vanmarcke, S.; Claes, K.; De Cae, S.; Demol, H.; Devos, S.; Fijalkowska, D.; Nerinckx, W.; Rossey, I.; Weyts, W.; Abdelnabi, R.; Jochmans, D.; Neyts, J.; Saelens, X.; van Schie, L.; Callewaert, N.
10.1101/2024.03.04.580093 — microbiology — Posted on 2024-03-05
4417 Microbial nitrogen guilds in the oceans: from the bathypelagic to the ocean surface
Rivas-Santisteban, J.; Fernandez-Gonzalez, N.; Laso-Perez, R.; Tamames, J.; Pedros-Alio, C.
10.1101/2024.03.05.583471 — microbiology — Posted on 2024-03-05
4418 Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.
Zande, P. V.; Gautier, C.; Kawar, N.; Maufrais, C.; Metzner, K.; Wash, E.; Beach, A. K.; Bracken, R.; Maciel, E. I.; Fernandes, C. M.; Solis, N. V.; Del Poeta, M.; Filler, S. G.; Berman, J.; Ene, I. V.; Selmecki, A.
10.1101/2024.03.05.583528 — microbiology — Posted on 2024-03-05
4420 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences
Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.
10.1101/2024.03.05.583455 — microbiology — Posted on 2024-03-05
4421 The latent stage of Toxoplasma gondii is targeted by the immune response and host protective
Shallberg, L. A.; Eberhard, J. N.; Winn, A.; Chandrasekaran, S.; Giuliano, C. J.; Merritt, E. F.; Willis, E.; Christian, D. A.; Aldridge, D. L.; Bunkofske, M.; Jacquet, M.; Dzierszinski, F.; Katifori, E.; Lourido, S.; Koshy, A. A.; Hunter, C. A.
10.1101/2024.03.05.583527 — microbiology — Posted on 2024-03-05
4423 A 10-valent composite mRNA vaccine against both influenza and COVID-19
Wang, Y.; Ma, Q.; Li, M.; Mai, Q.; Ma, L.; Zhang, H.; Zhong, H.; Cheng, N.; Feng, P.; Guan, P.; Wu, S.; Zhang, L.; Dai, J.; Zhang, B.; Pan, W.; Yang, Z.
10.1101/2024.03.05.583547 — microbiology — Posted on 2024-03-05
4426 The Role of Inhibition in fMRI Resting-State Negative Correlations
Harita, S.; Momi, D.; Wang, Z.; Bastiaens, S. P.; Griffiths, J. D.
10.1101/2024.03.01.583030 — neuroscience — Posted on 2024-03-05
4435 Bacteroides vesicles promote functional alterations in gut microbiota composition
Shagaleeva, O. Y.; Kashatnikova, D. A.; Kardonsky, D. A.; Efimov, B. A.; Ivanov, V. A.; Evsiev, S. S.; Zubkov, E. A.; Abramova, O. V.; Zorkina, Y. A.; Morozova, A. Y.; Vorobeva, E. A.; Silantiev, A. S.; Kolesnikova, I. V.; Markelova, M. I.; Olekhnovich, E. I.; Morozov, M. D.; Zoruk, P. Y.; Boldyreva, D. I.; Vanyushkina, A.; Chaplin, A. V.; Grigoryeva, T. V.; Zakharzhevskaya, N. B.
10.1101/2024.03.05.583531 — microbiology — Posted on 2024-03-05
4436 Early-branching cyanobacteria up-regulate superoxide dismutase activity under a simulated early Earth anoxic atmosphere.
Tamanna, S. S.; Boden, J. S.; Kaiser, K. M.; Wannicke, N.; Hoering, J.; Sanchez-Baracaldo, P.; Deponte, M.; Frankenberg-Dinkel, N.; Gehringer, M. M.
10.1101/2024.03.05.583491 — microbiology — Posted on 2024-03-05
4438 Salmonella Typhimurium infection inhibits macrophage IFNbeta signaling in a TLR4-dependent manner
Shuster, M.; Lyu, Z.; Augenstreich, J.; Mathur, S.; Ganesh, A.; Ling, J.; Briken, V.
10.1101/2024.03.05.583530 — microbiology — Posted on 2024-03-05
4439 Seasonal exometabolites are regulated by essential microbial metabolisms in the oligotrophic ocean
McParland, E. L.; Wittmers, F.; Bolanos, L. M.; Carlson, C. A.; Giovannoni, S. J.; Michelsen, M.; Parsons, R.; Kido Soule, M. C.; Swarr, G. J.; Temperton, B.; Vergin, K.; Worden, A. Z.; Longnecker, K.; Kujawinski, E. B.
10.1101/2024.03.05.583599 — microbiology — Posted on 2024-03-05
4440 Biological modifications of the immune response to COVID-19 vaccine in patients treated with anti-CD20 agents and immune-checkpoint inhibitors
Ravera, F.; Dameri, M.; Lombardo, I.; Stabile, M.; Fallani, N.; Scarsi, C.; Cigolini, B.; Gentilcore, G.; Domnich, A.; Zullo, L.; Cella, E.; Francia, G.; Montanari, E.; Orsi, A.; Bellodi, A.; Ferrando, F.; Rinchai, D.; Ballerini, F.; Bruzzone, B.; Chaussabel, D.; Grivel, J.-C.; Genova, C.; Lemoli, R.; Bedognetti, D.; Ballestrero, A.; Ferrando, L.; Zoppoli, G.
10.1101/2024.03.05.583494 — immunology — Posted on 2024-03-05
4441 SARS-CoV-2 modulates NK cell responses via induction of HLA-E and triggers expansion of adaptive NK cells during acute infection
Hasan, M. Z.; Claus, M.; Kruger, N.; Reusing, S.; Gall, E.; Bade-Doding, C.; Braun, A.; Watzl, C.; Uhrberg, M.; Walter, L.
10.1101/2024.03.04.583260 — immunology — Posted on 2024-03-05
4443 A Panoramic View of Cell Population Dynamics in Mammalian Aging
Zhang, Z.; Schaefer, C.; Jiang, W.; Lu, Z.; Lee, J.; Sziraki, A.; Abdulraouf, A.; Wick, B.; Haeussler, M.; Li, Z.; Molla, G.; Satija, R.; Zhou, W.; Cao, J.
10.1101/2024.03.01.583001 — genomics — Posted on 2024-03-05
4444 Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies
Nazeen, S.; Wang, X.; Zielinski, D.; Lam, I.; Xu, P.; Ethier, E.; Strom, R.; Zanella, C. A.; Nithianandam, V.; Ritter, D.; Henderson, A.; Saurat, N.; Nutter-Upham, A.; Benyamini, H.; Copty, J.; Ravishankar, S.; Morrow, A.; Mitchel, J.; Neavin, D.; Gupta, R.; Farbehi, N.; Grundman, J.; Myers, R. H.; Scherzer, C. R.; Trojanowski, J. Q.; Van Deerlin, V. M.; Cooper, A. A.; Lee, E. B.; Erlich, Y.; Lindquist, S.; Peng, J.; Geschwind, D. H.; Powell, J.; Studer, L.; Feany, M. B.; Sunyaev, S. R.; Khurana, V.
10.1101/2024.03.03.583145 — genomics — Posted on 2024-03-05
4447 Nanopore sequencing with unique molecular identifiers enables accurate mutation analysis and haplotyping in the complex Lipoprotein(a) KIV-2 VNTR
Amstler, S.; Streiter, G.; Pfurtscheller, C.; Forer, L.; Di Maio, S.; Weissensteiner, H.; Paulweber, B.; Schoenherr, S.; Kronenberg, F.; Coassin, S.
10.1101/2024.03.01.582741 — genomics — Posted on 2024-03-05
4448 Activity of spinal RORβ neurons is related to functional improvements following combination treatment after complete SCI
Stachowski, N. J.; Wheel, J. H.; Atoche, S.; Yao, L.; Garcia-Ramirez, D. L.; Giszter, S. F.; Dougherty, K. J.
10.1101/2024.03.01.583033 — neuroscience — Posted on 2024-03-05
4450 Molecular control of temporal integration matches decision-making to motivational state
Gautham, A. K.; Miner, L. E.; Franco, M. N.; Thornquist, S. C.; Crickmore, M. A.
10.1101/2024.03.01.582988 — neuroscience — Posted on 2024-03-05
4451 Disentangling plant response to biotic and abiotic stress using HIVE, a novel tool to perform unpaired multi-omics integration
Calia, G.; Zotta Mota, A. P.; Seynabou, M.; Nguyen, H. T.; Ghat, A.; Schuler, H.; Gwizdek, C.; Brasileiro, A.; Guimares, P.; BOTTINI, S.
10.1101/2024.03.04.583290 — plant biology — Posted on 2024-03-05
4453 Fibroblasts as an in vitro model of circadian genetic and genomic studies
Francia, M.; Bot, M.; Boltz, T.; De La Hoz, J. F.; Boks, M.; Kahn, R.; Ophoff, R.
10.1101/2023.05.19.541494 — genomics — Posted on 2024-03-05
4455 Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control
Vietri Rudan, M.; Sipilä, K. H.; Philippeos, C.; Ganier, C.; Negri, V. A.; Watt, F. M.
10.1101/2023.12.19.572393 — cell biology — Posted on 2024-03-05
4457 Spatiotemporally-specific cortical-subthalamic coupling differentiates aspects of speech performance
Vissani, M.; Bush, A.; Lipski, W. J.; Fischer, P.; Neudorfer, C.; Holt, L. L.; Fiez, J. A.; Turner, R. S.; Richardson, R. M.
10.1101/2023.10.18.562969 — neuroscience — Posted on 2024-03-05
4458 Artificial neural network for brain-machine interface consistently produces more naturalistic finger movements than linear methods
Temmar, H.; Willsey, M. S.; Costello, J. T.; Mender, M. J.; Cubillos, L. H.; Lam, J. L.; Wallace, D. M.; Kelberman, M. M.; Patil, P. G.; Chestek, C. A.
10.1101/2024.03.01.583000 — neuroscience — Posted on 2024-03-05
4462 Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction
Hwang, S.-Y.; Jeon, K.-H.; Lee, H.-J.; Moon, I.; Jung, S.; Kim, S.-A.; Jo, H.; Park, S.; Ahn, M.; Kwak, S.-Y.; Na, Y.; Kwon, Y.
10.1101/2024.03.01.583029 — pharmacology and toxicology — Posted on 2024-03-05
4463 Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior
Zeledon, E. V.; Baxt, L. A.; Khan, T. A.; Michino, M.; Miller, M.; Huggins, D. J.; Jiang, C. S.; Vosshall, L. B.; Duvall, L. B.
10.1101/2024.02.28.582529 — pharmacology and toxicology — Posted on 2024-03-05
4465 Bacteria in honeybee crops are decoupled from those in floral nectar and bee mouths
Warren, M. L.; Tsuji, K.; Decker, L. E.; Kishi, M.; Yang, J.; Howe, A. C.; Fukami, T.
10.1101/2024.03.01.583024 — ecology — Posted on 2024-03-05
4466 FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans
Kimmich, M. J.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.
10.1101/2024.02.29.582848 — cell biology — Posted on 2024-03-05
4470 Inflammation promotes aging-associated oncogenesis in the lung.
Pham-Danis, C.; Chia, S. B.; Scarborough, H. A.; Danis, E.; Nemkov, T.; Kleczko, E. K.; Navarro, A.; Goodspeed, A.; Bonney, E. A.; Dinarello, C. A.; Marchetti, C.; Nemenoff, R. A.; Hansen, K. A.; DeGregori, J.
10.1101/2024.03.01.583044 — cancer biology — Posted on 2024-03-05
4472 Expanding the Drosophila toolkit for dual control of gene expression
Zirin, J.; Jusiak, B.; Lopes, R.; Ewen-Campen, B.; Bosch, J. A.; Risbeck, A.; Forman, C.; Villalta, C.; Hu, Y.; Perrimon, N.
10.1101/2023.08.15.553399 — genetics — Posted on 2024-03-05
4474 A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms
McSwiggen, D. T.; Liu, H.; Tan, R.; Agramunt Puig, S.; Akella, L. B.; Berman, R.; Bretan, M.; Chen, H.; Darzacq, X.; Ford, K.; Godbey, R.; Gonzalez, E.; Hanuka, A.; Heckert, A.; Ho, J. J.; Johnson, S. L.; Kelso, R.; Klammer, A.; Krishnamurthy, R.; Li, J.; Lin, K.; Margolin, B.; McNamara, P.; Meyer, L.; Pierce, S. E.; Sule, A.; Stashko, C.; Tang, Y.; Anderson, D. J.; Beck, H.
10.1101/2023.01.05.522916 — cell biology — Posted on 2024-03-05
4476 Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure
Shim, A. R.; Frederick, J.; Pujadas, E. M.; Kuo, T.; Ye, I. C.; Pritchard, J. A.; Dunton, C. L.; Carrillo Gonzalez, P.; Acosta, N.; Jain, S.; Anthony, N. M.; Almassalha, L. M.; Szleifer, I.; Backman, V.
10.1101/2024.03.01.582995 — biophysics — Posted on 2024-03-05
4477 Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA
Shepherd, J.; Guilbaud, S.; Zhou, Z.; Howard, J.; Burman, M.; Schaefer, C.; Kerrigan, A.; Steele-King, C.; Noy, A.; Leake, M. C.
10.1101/2024.01.18.576226 — biophysics — Posted on 2024-03-05
4478 Gut Microbiome-Driven Metabolites Influence Skin Pigmentation in TYRP1 Mutant Oujiang Color Common Carp
Mandal, R. N.; Ke, J.; Kanika, N. H.; Hou, X.; Zhang, Z.; Zhang, P.; Chen, H.; Zeng, C.; Chen, X.; Wang, J.; Wang, C.
10.1101/2024.03.01.583018 — genetics — Posted on 2024-03-05
4480 Electrocorticographic and Astrocytic Signatures of Stearoyl-CoA Desaturase Inhibition in the Triple Transgenic Mouse Model of Alzheimer's Disease
Hector, A.; da Costa Caiado, M. J.; Leduc, T.; Delignat-Lavaud, B.; Dufort-Gervais, J.; Bourguignon, C.; Lina, J.-M.; Fernandes, K.; Brouillette, J.; Mongrain, V.
10.1101/2024.03.01.582986 — neuroscience — Posted on 2024-03-05
4481 Human brain aging heterogeneity observed from multi-region omics data reveals a subtype closely related to Alzheimer's disease
Peng, S.; Wang, E.; Wang, M.; Wang, X.; Yu, K.; Fu, Y.; Poudel, S.; Ho, L.; Narayan, S.; Huffman, D.; Gaiteri, C.; Bennett, D. A.; Ehrlich, M. E.; Haroutunian, V.; Peng, J.; Zhang, B.; Tu, Z.
10.1101/2024.03.01.582970 — neuroscience — Posted on 2024-03-05
4482 The lipidome of posttraumatic stress disorder
Bhargava, A.; Knapp, J. D.; Fiehn, O.; Neylan, T. C.; Inslicht, S. S.
10.1101/2024.02.23.581833 — systems biology — Posted on 2024-03-05
4484 Do seabirds dream of artificial lights? Understanding light preferences of Procellariiformes
Atchoi, E.; Mitkus, M.; Machado, B.; Medeiros, V.; Garcia, S.; Juliano, M.; Bried, J.; Rodriguez, A.
10.1101/2024.03.01.582998 — animal behavior and cognition — Posted on 2024-03-05
4485 The Genetic Basis of Incipient Sexual Isolation in Drosophila melanogaster
Yamamoto, A.; Huang, W.; Carbone, M. A.; Anholt, R. R. H.; Mackay, T.
10.1101/2024.03.01.582979 — genetics — Posted on 2024-03-05
4486 RNA polymerase III is involved in regulating Plasmodium falciparum virulence
Diffendall, G. M.; Claes, A.; Barcons-Simon, A.; Nyarko, P.; Dingli, F.; Santos, M.; Loew, D.; Claessens, A.; Scherf, A.
10.1101/2023.07.18.549525 — microbiology — Posted on 2024-03-05
4488 The Molecular Landscape of Cellular Metal Ion Biology
Aulakh, S. K.; Lemke, O.; Szyrwiel, L.; Kamrad, S.; Chen, Y.; Hartl, J.; Muelleder, M.; Nielsen, J.; Ralser, M.
10.1101/2024.02.29.582718 — systems biology — Posted on 2024-03-05
4489 Identification of RACK1A as a component of the auxin-ethylene crosstalk regulating apical hook development in Arabidopsis thaliana
Ma, Q.; Liu, S.; Raggi, S.; Doyle, S. M.; Parizkova, B.; Barange, D. K.; Wilkinson, E. G.; Crespo Garcia, I.; Bygdell, J.; Wingsle, G.; Boer, D. R.; Strader, L. C.; Almqvist, F.; Novak, O.; Robert, S.
10.1101/2024.03.04.582885 — plant biology — Posted on 2024-03-05
4490 Regulation of Arabidopsis polyamine acetylation by NATA1 and NATA2
Hameed, U. F. S.; Luo, Y.-R.; Yan, J.; Guzman-Vega, F. J.; Aleksenko, E.; Briozzo, P.; MORERA, S.; Jander, G.; Arold, S. T.
10.1101/2024.03.04.583282 — plant biology — Posted on 2024-03-05
4492 Identification of new resistance QTL regions in loquat cultivar Champagne against Pseudomonas syringae pv. eriobotryae group C
Koga, S.; Kawaguchi, R.; Tanaka, T.; Moriya, S.; Hiehata, N.; Kabashima, K.; Nagano, A. J.; Nagano, Y.; Fukuda, S.
10.1101/2024.03.04.583427 — plant biology — Posted on 2024-03-05
4495 Spray-induced gene silencing (SIGS) as a tool for the management of Pine Pitch Canker forest disease
Bocos Asenjo, I. T.; Amin, H.; Mosquera, S.; Diez Hermano, S.; Ginesy, M.; Diez, J. J.; Nino Sanchez, J.
10.1101/2024.03.05.583474 — plant biology — Posted on 2024-03-05
4503 Variations of floral temperature in changing weather conditions
Harrap, M. J. M.; de Vere, N.; Hempel de Ibarra, N.; Whitney, H. M.; Rands, S. A.
10.1101/2024.03.04.583410 — plant biology — Posted on 2024-03-05
4506 Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon
Thieme, M.; Minadakis, N.; Himber, C.; Keller, B.; Xu, W.; rutowicz, K.; Matteoli, C.; Boehrer, M.; Rymen, B.; Laudencia-Chingcuanco, D.; Vogel, J. P.; Sibout, R.; Stritt, C.; Blevins, T.; Roulin, A. C.
10.1101/2023.09.25.559196 — genomics — Posted on 2024-03-05
4508 Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells
Donnelly, H.; Ross, E.; Xiao, Y.; Hermantara, R.; Taqi, A. F. J. M. A.; Doherty-Boyd, W. S.; Cassels, J.; Tsimbouri, P. M.; Dunn, K. M.; Hay, J.; Cheng, Z. A.; Jain, N.; West, C. C.; Wheadon, H.; Michie, A. M.; Peault, B.; West, A. G.; Salmeron-Sanchez, M.; Dalby, M. J.
10.1101/2022.07.28.501818 — bioengineering — Posted on 2024-03-05
4510 Metabolic adaptation pilots the differentiation of human hematopoietic cells
Racine, L.; Parmentier, R.; Niphadkar, S.; Laxman, S.; Martignoles, J.-A.; Delhommeau, F.; Paldi, A.
10.1101/2023.09.17.558120 — cell biology — Posted on 2024-03-05
4511 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus
Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.
10.1101/2023.08.22.554078 — molecular biology — Posted on 2024-03-05
4516 Increased Enhancer-Promoter Interactions during Developmental Enhancer Activation in Mammals
Chen, Z.; Snetkova, V.; Bower, G.; Jacinto, S.; Clock, B.; Dizehchi, A.; Barozzi, I.; Mannion, B. J.; Alcaina-Caro, A.; Lopez-Rios, J.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.; Kvon, E. Z.
10.1101/2022.11.18.516017 — genomics — Posted on 2024-03-04
4517 Single-cell multiplex chromatin and RNA interactions in aging human brain
Wen, X.; Luo, Z.; Zhao, W.; Calandrelli, R.; Nguyen, T.; Wan, X.; Richard, J. L. C.; Zhong, S.
10.1101/2023.06.28.546457 — genomics — Posted on 2024-03-04
4522 A synthesis on alien mammals threatened in their native range
Tedeschi, L.; Lenzner, B.; Schertler, A.; Biancolini, D.; Rondinini, C.; Essl, F.
10.1101/2024.03.04.582492 — ecology — Posted on 2024-03-05
4523 Easy, fast and reproducible Stochastic Cellular Automata with 'chouca'
Genin, A.; Dupont, G.; Valencia, D.; Zucconi, M.; Avila-Thieme, M. I.; Navarrete, S.; Wieters, E.
10.1101/2023.11.08.566206 — ecology — Posted on 2024-03-05
4526 The inflammatory micro-environment induced by targeted CNS radiotherapy is underpinned by disruption of DNA methylation
Millner, T. O.; Panday, P.; Xiao, Y.; Boot, J. R.; Nicholson, J.; Arpe, Z.; Stevens, P.; Rahman, N.; Zhang, X.; Mein, C.; Kitchen, N.; McEvoy, A. W.; McKintosh, E.; McKenna, G.; Paraskevopoulos, D.; Lewis, R.; Badodi, S.; Marino, S.
10.1101/2024.03.04.581366 — neuroscience — Posted on 2024-03-05
4529 Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines
Kalkan, F. N.; Yildiz, M. S.; Wood, N. E.; Farid, M.; McCoy, M.; Zhang, C.; Lin, M.; Posner, B.; Chung, S. S.; Toprak, E.
10.1101/2024.02.23.581821 — cancer biology — Posted on 2024-03-05
4530 Conformational Ensembles Reveal the Origins of Serine Protease Catalysis
Du, S.; Kretsch, R. C.; Parres-Gold, J.; Pieri, E.; Cruzeiro, V. W. D.; Zhu, M.; Pinney, M. M.; Yabukarski, F.; Schwans, J. P.; Martinez, T. J.; Herschlag, D.
10.1101/2024.02.28.582624 — biophysics — Posted on 2024-03-05
4532 Identification and characterisation of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes, supported by short- and long-read transcriptome data
Jutersek, M.; Gerasymenko, I. M.; Petek, M.; Haumann, E.; Vacas Gonzalez, S.; Kallam, K.; Gianoglio, S.; Navarro-Llopis, V.; Navarro Fuertes, I.; Patron, N.; Orzaez, D.; Gruden, K.; Warzecha, H.; Baebler, S.
10.1101/2023.06.09.544309 — biochemistry — Posted on 2024-03-05
4534 Physiological traits and their relationships vary along an elevational gradient within and among Fijian bee species
da Silva, C. R. B.; Beaman, J. E.; Tuiwawa, M.; Stevens, M. I.; Schwarz, M. P.; Gloag, R.; Kellermann, V.; Alton, L. A.
10.1101/2022.07.27.501487 — evolutionary biology — Posted on 2024-03-04
4536 A Parasite Odyssey: An RNA virus concealed in Toxoplasma gondii
Gupta, P.; Hiller, A.; Chowdhury, J.; Lim, D.; Lim, D. Y.; Saeij, J. P.; Babaian, A.; Rodriguez, F.; Pereira, L.; Morales, A.
10.1101/2023.09.17.558162 — microbiology — Posted on 2024-03-04
4537 Exploring neural tracking of acoustic and linguistic speech representations in individuals with post-stroke aphasia
Kries, J.; De Clercq, P.; Gillis, M.; Vanthornhout, J.; Lemmens, R.; Francart, T.; Vandermosten, M.
10.1101/2023.03.01.530707 — neuroscience — Posted on 2024-03-04
4538 Spatial arrangement of the whiskers of harbor seals (Phoca vitulina) compared to whisker arrangements of mice (Mus musculus) and rats (Rattus norvegicus)
Graff, M. M.; Belli, H. M.; Wieskotten, S.; Bresee, C. S.; Krüger, Y.; Janssen, T. L.; Dehnhardt, G.; Hartmann, M. J. Z.
10.1101/2024.01.15.575743 — neuroscience — Posted on 2024-03-04
4540 Competitive Amplification Networks enable molecular pattern recognition with PCR
Goertz, J. P.; Sedgwick, R.; Smith, F.; Kaforou, M. P.; Wright, V. J.; Herberg, J. A.; Kote-Jarai, Z.; Eeles, R.; Levin, M.; Misener, R.; van der Wilk, M.; Stevens, M. M.
10.1101/2023.06.29.546934 — bioengineering — Posted on 2024-03-04
4542 RNA G-quadruplexes and calcium ions synergistically induce Tau phase transition in vitro
Yabuki, Y.; Matsuo, K.; Komiya, G.; Kudo, K.; Hori, K.; Ikenoshita, S.; Kawata, Y.; Mizobata, T.; Shioda, N.
10.1101/2024.03.01.582861 — biochemistry — Posted on 2024-03-04
4543 Coevolution of longevity and female germline maintenance
Baur, J.; Koppik, M.; Savkovic, U.; Dordevic, M.; Stojkovic, B.; Berger, D.
10.1101/2023.12.03.569746 — evolutionary biology — Posted on 2024-03-04
4544 Endocardial HDAC3 is required for myocardial trabeculation
Jang, J.; Bentsen, M.; Kim, Y. J.; Kim, E.; Garg, V.; Cai, C.-L.; Looso, M.; Li, D.
10.1101/2023.04.12.536668 — developmental biology — Posted on 2024-03-04
4545 A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects
Kathiriya, I. S.; Dominguez, M. H.; Rao, K. S.; Muncie-Vasic, J. M.; Devine, W. P.; Hu, K. M.; Hota, S. K.; Garay, B. I.; Quintero, D.; Goyal, P.; Matthews, M. N.; Thomas, R.; Sukonnik, T.; Miguel-Perez, D.; Winchester, S.; Brower, E. F.; Forjaz, A.; Wu, P.-H.; Wirtz, D.; Kiemen, A. L.; Bruneau, B. G.
10.1101/2024.02.05.578995 — developmental biology — Posted on 2024-03-04
4546 Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis
Dill-McFarland, K. A.; Simmons, J. D.; Peterson, G. J.; Nguyen, F. K.; Campo, M.; Benchek, P.; Stein, C.; Vaisar, T.; Mayanja-Kizza, H.; Boom, W. H.; Hawn, T.
10.1101/2024.02.27.582348 — immunology — Posted on 2024-03-04
4547 Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Erice, P. A.; Huang, X.; Seasock, M. J.; Robertson, M. J.; Tung, H.-Y.; Perez-Negron, M. A.; Lotlikar, S. L.; Corry, D. B.; Kheradmand, F.; Rodriguez, A.
10.1101/2023.10.12.562059 — immunology — Posted on 2024-03-04
4551 Cell class-specific electric field entrainment of neural activity
Lee, S. Y.; Kozalakis, K.; Baftizadeh, F.; Campagnola, L.; Jarsky, T.; Koch, C.; Anastassiou, C. A.
10.1101/2023.02.14.528526 — neuroscience — Posted on 2024-03-04
4553 Graph perceiver network for lung tumor and bronchial premalignant lesion stratification from histopathology
Gindra, R. H.; Zheng, Y.; Green, E. J.; Reid, M. E.; Mazzilli, S. A.; Merrick, D. T.; Burks, E. J.; Kolachalama, V. B.; Beane, J. E.
10.1101/2023.10.16.562550 — pathology — Posted on 2024-03-04
4555 Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
Prithiviraj, S.; Garcia Garcia, A.; Linderfalk, K.; Yiguang, B.; Ferveur, S.; Falck, L. N.; Subramaniam, A.; Mohlin, S.; Gil, D. H.; Dupard, S. J.; Raina, D. B.; Bourgine, P. E.
10.1101/2023.07.28.550935 — bioengineering — Posted on 2024-03-04
4559 Cytochrome oxidase requirements in Bordetella reveal insights into evolution towards life in the mammalian respiratory tract
McKay, L. S.; Spandrio, A. R.; Johnson, R. M.; Sobran, M. A.; Marlatt, S.; Mote, K. B.; Dedloff, M. R.; Nash, Z. M.; Julio, S. M.; Cotter, P. A.
10.1101/2024.02.29.582880 — microbiology — Posted on 2024-03-04
4563 Metformin treatment results in distinctive skeletal muscle mitochondrial remodeling in rats with different intrinsic aerobic capacities
Bubak, M. P.; Davidyan, A.; O'Reilly, C. L.; Mondal, S. A.; Kest, J.; Doidge, S. M.; Borowik, A. K.; Taylor, M. T.; Voloviceva, E.; Kinter, M. T.; Britton, S. L.; Koch, L. G.; Stout, M. B.; Lewis, T. L.; Miller, B. F.
10.1101/2024.03.01.582957 — physiology — Posted on 2024-03-04
4564 Unveiling the genome assembly of the polyploid and quarantine root-knot nematode, Meloidogyne enterolobii
Poullet, M.; Gopal, H.; Rancurel, C.; Sallaberry, M.; Lopez-Roques, C.; Lledo, J.; Kiewnick, S.; Danchin, E.
10.1101/2024.03.01.582926 — genomics — Posted on 2024-03-04
4570 The Molecular Determinants of a Universal Prion Acceptor
Arshad, H.; Patel, Z.; Al-Azzawi, Z. A. M.; Li, L.; Amano, G.; Mehra, S.; Eid, S.; Schmitt-Ulms, G.; Watts, J. C.
10.1101/2024.03.01.582976 — neuroscience — Posted on 2024-03-04
4573 The power and limits of predicting exon-exon interactions using protein 3D structures
Liebold, J.; Del Moral-Morales, A.; Manalastas-Cantos, K.; Tsoy, O.; Kurtz, S.; Baumbach, J.; Newaz, K.
10.1101/2024.03.01.582917 — bioinformatics — Posted on 2024-03-04
4574 Community assesses differential cell communication using large multi-sample case-control scRNAseq datasets.
Solovey, M.; Celik, M. A.; Salcher, F. R.; Abdelfattah, M.; Ismail, M.; Scialdone, A.; Ziemann, F.; Colome-Tatche, M.
10.1101/2024.03.01.582941 — bioinformatics — Posted on 2024-03-04
4582 Wolbachia infection in Aedes aegypti does not affect its vectorial capacity for Dirofilaria immitis
Shirozu, T.; Regilme, M. A. F.; Ote, M.; Sasaki, M.; Soga, A.; Bochimoto, H.; Kawabata, H.; Umemiya-Shirafuji, R.; Kanuka, H.; Fukumoto, S.
10.1101/2024.03.04.583272 — microbiology — Posted on 2024-03-04
4583 The Interplay Between Nutrition and the Midgut Microbiome of the Mosquito Aedes aegypti Reveals Putative Symbionts.
Salgado, J. F. M.; Premkrishnan, B. N. V.; Oliveira, E. L.; Vettath, V. K.; Goh, F. G.; Hou, X.; Drautz-Moses, D. I.; Cai, Y.; Schuster, S. C.; M., A. C.
10.1101/2024.03.04.583003 — microbiology — Posted on 2024-03-04
4588 Th17 cells with a pathogenic signature in joints of ZAP-70 mutant arthritic mice harbor unique TCR repertoires that share features with WT Tregs
Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.
10.1101/2024.03.01.582868 — immunology — Posted on 2024-03-04
4589 Real-time control of a hearing instrument with EEG-based attention decoding
Hjortkjaer, J.; Wong, D. D. E.; Catania, A.; Marcher-Rorsted, J.; Ceolini, E.; Fuglsang, S. A.; Kiselev, I.; Di Liberto, G.; Liu, S.-C.; Dau, T.; Slaney, M.; de Cheveigne, A.
10.1101/2024.03.01.582668 — neuroscience — Posted on 2024-03-04
4590 Repeated Exposure Decreases Aesthetic Chills Likelihood but Increases Intensity
Schoeller, F.; Christov-Moore, L.; Lynch, C.; Jain, A.; Diot, T.; Reggente, N.
10.1101/2024.03.01.582918 — neuroscience — Posted on 2024-03-04
4592 Photothrombosis induced cortical stroke produces electrographic epileptic biomarkers in mice
Shaw, D. C.; Kondabolu, K.; Walsh, K. G.; Shi, W.; Rillosi, E.; Hsiung, M.; Eden, U.; Richardson, R. M.; Kramer, M. A.; Chu, C. J.; Han, X.
10.1101/2024.03.01.582958 — neuroscience — Posted on 2024-03-04
4593 Astrocytic thrombospondins 1 and 2 are required for cortical synapse development controlling instrumental performance
Lawal, O. O.; Ulloa Severino, F. P.; Wang, S.; Bindu, D. S.; Sakers, K.; Johnson, S. A.; Yin, H. H.; Eroglu, C.
10.1101/2024.03.01.582935 — neuroscience — Posted on 2024-03-04
4594 Element accumulation in the tracheal and bronchial cartilages of monkeys
Azuma, C.; Oishi, T.; Tohno, Y.; Ke, L.; Zhao, X.-z.; Minami, T.; Horii-Hayashi, N.; Inoue, K.
10.1101/2024.03.01.582912 — zoology — Posted on 2024-03-04
4596 A Targeted Genome-scale Overexpression Platform for Proteobacteria
Banta, A. B.; Myers, K. S.; Ward, R. D.; Cuellar, R. A.; Freeh, C. C.; Bacon, E. E.; Peters, J. M.
10.1101/2024.03.01.582922 — systems biology — Posted on 2024-03-04
4597 Rapid Identification of Genomic Alterations in Tumors affecting lymphocyte Infiltration (RIGATonI)
Vella, R.; Hoskins, E.; Yu, L.; Reeser, J. W.; Wing, M. R.; Samorodnitsky, E.; Stein, L.; Paruchuri, A.; ORIEN Investigators, ; Churchman, M.; Single, N.; Chen, W.; Freud, A. G.; Roychowdhury, S.
10.1101/2024.03.02.583103 — bioinformatics — Posted on 2024-03-04
4598 Revised Mechanism of Hydroxyurea Induced Cell Cycle Arrest and an Improved Alternative
Shaw, A. E.; Whitted, J. E.; Mihelich, M. N.; Reitman, H. J.; Timmerman, A. J.; Schauer, G. D.
10.1101/2024.03.02.583010 — biochemistry — Posted on 2024-03-04
4600 Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing
Rohm, D.; Black, J. B.; McCutcheon, S. R.; Barrera, A.; Morone, D. J.; Nuttle, X.; de Esch, C. E.; Tai, D. J. C.; Talkowski, M. E.; Iglesias, N.; Gersbach, C. A.
10.1101/2024.03.03.583177 — genomics — Posted on 2024-03-04
4601 Repeated loss of function at HD mating-type genes and of recombination suppression without mating-type locus linkage in anther-smut fungi
Lucotte, E. A.; Jay, P.; Rougemont, Q.; Boyer, L.; Cornille, A. A.; Snirc, A.; Labat, A.; Chahine, E.; Duhamel, M.; Gendelman, J.; Hayes, R. K.; Perlin, M. H.; Hood, M.; Rodriguez de la Vega, R. C.; Giraud, T.
10.1101/2024.03.03.583181 — evolutionary biology — Posted on 2024-03-04
4602 Detection of pathogens and antimicrobial resistant genes from urine within 5 hours using Nanopore sequencing
Bellankimath, A. B.; Chapagain, C.; Branders, S.; Ali, J.; Wilson, R. C.; Johansen, T. E. B.; Ahmad, R.
10.1101/2024.03.04.582689 — microbiology — Posted on 2024-03-04
4603 A resource to enable chemical biology and drug discovery of WDR Proteins
Arrowsmith, C. H.; Ackloo, S.; Li, F.; Szewczyk, M.; Seitova, A.; Loppnau, P.; Zeng, H.; Ahmad, S.; Beldar, S.; Bolotokova, A.; Chau, I.; Dehghani-Tafti, S.; Dong, A.; Ghiabi, P.; Gibson, E.; Green, S. R.; Herasymenko, O.; Houliston, S.; Hutchinson, A.; Kimani, S. W.; Kutera, M.; Kwak, H. A.; Li, Y.; Machado, R. A.; Perveen, S.; Righetto, G. L.; Shrestha, S.; Silva, M.; Yadav, M.; Yazdi, A. K.; Santhakumar, V.; Edwards, A. M.; Barsyte-Lovejoy, D.; Schapira, M.; Brown, P. J.; Halabelian, L.; Xu, J.; Feng, J. A.; Kearnes, S.; Thompson, J.; Torng, W.; Gilmer, J.; Riley, P.; Watson, I.; Arnautova,
10.1101/2024.03.03.583197 — biochemistry — Posted on 2024-03-04
4605 The Role of the Co-Chaperone DNAJB11 in Polycystic Kidney Disease: Molecular Mechanisms and Cellular Origin of Cyst Formation
Busch, T.; Neubauer, B.; Schmitt, L.; Cascante, I.; Knoblich, L.; Wegehaupt, O.; Schoeler, F.; Tholen, S.; Hofherr, A.; Schell, C.; Schilling, O.; Westermann, L.; Kottgen, M.
10.1101/2024.03.04.582938 — molecular biology — Posted on 2024-03-04
4606 Engineering customized viral receptors for various coronaviruses
Liu, P.; Huang, M.; Guo, H.; Si, J.; Chen, Y.; Wang, C.; Yu, X.; Shi, L.; Xiong, Q.; Ma, C.; Tong, F.; Liu, C.; Chen, J.; Guo, M.; Li, J.; Shi, Z.-L.; Yan, H.
10.1101/2024.03.03.583237 — microbiology — Posted on 2024-03-04
4607 Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms
Suzuki, M.; Okamura, S.; Gis, T.; Sasaki, H.; Lee, S.; Yoshida, A.; Goto, S.; Nakagawa, T.; Ikawa, M.; Kamitani, W.; Takekawa, S.; Yamanishi, K.; Ebina, H.
10.1101/2024.03.03.582873 — microbiology — Posted on 2024-03-04
4609 Involvement of ArlI, ArlJ, and CirA in Archaeal Type-IV Pilin-Mediated Motility Regulation
Chatterjee, P.; Garcia, M.; Cote, J.; Yun, K.; Legerme, G.; Habib, R.; Tripepi, M.; Young, C.; Kulp, D. W.; Dyall-Smith, M.; Pohlschroder, M.
10.1101/2024.03.04.583388 — microbiology — Posted on 2024-03-04
4610 Identification of Southeast Asian Anopheles mosquito species using MALDI-TOF mass spectrometry
Chaumeau, V.; Piarroux, M.; Kulabkeeree, T.; Sawasdichai, S.; Inta, A.; Watthanaworawit, W.; Nosten, F.; Piarroux, R.; Nabet, C.
10.1101/2024.03.04.583274 — microbiology — Posted on 2024-03-04
4613 Uncovering the class II-bacteriocin predatiome in salivarius streptococci
Damoczi, J.; Knoops, A.; Martou, M.-S.; Jamaux, F.; Gabant, P.; Mahillon, J.; Mignolet, J.; Hols, P.
10.1101/2024.03.04.583286 — microbiology — Posted on 2024-03-04
4614 A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis
Takada, H.; Paternoga, H.; Fujiwara, K.; Nakamoto, J. A.; Park, E. N.; Dimitrova-Paternoga, L.; Beckert, B.; Saarma, M.; Tenson, T.; Buskirk, A.; Atkinson, G. C.; Chiba, S.; Wilson, D. N.; Hauryliuk, V.
10.1101/2024.03.03.583159 — microbiology — Posted on 2024-03-04
4615 Integrative in vivo analysis of the ethanolamine utilization bacterial microcompartment in Escherichia coli.
Jallet, D.; Soldan, V.; Shayan, R.; Stella, A.; Ismail, N.; Zenati, R.; Cahoreau, E.; Schiltz, O.; Balor, S.; Millard, P.; Heux, S.
10.1101/2024.03.04.583360 — microbiology — Posted on 2024-03-04
4616 Heterogeneous hybrid immunity against Omicron variant JN.1 at 11 months following breakthrough infection
He, X.; Jiang, J.; Li, G.; Liu, J.; Gan, J.; Zhou, L.; Bai, C.; Zi, Q.; Mou, X.; Zeng, S.; Yuan, J.; Zhou, C.; Li, Y.; Zhu, G.; Zhao, R.; Yang, L.; Wu, J.; Zhang, H.; Xian, J.; Wang, Z.; Qi, Q.; Liu, Y.; Yu, J.; Liu, D.; Li, W.
10.1101/2024.03.02.583082 — immunology — Posted on 2024-03-04
4617 Physics-driven structural docking and protein language models accelerate antibody screening and design for broad-spectrum antiviral therapy
Mubarak, H. F.; Tan, W.; Hoffmann, A. D.; Wei, J.; El-Shennawy, L.; Squires, J. R.; Sun, Y.; Dashzeveg, N. K.; Simonton, B.; Jia, Y.; Iyer, R.; Xu, Y.; Nicolaescu, V.; Elli, D.; Randall, G. C.; Schipma, M. J.; Swaminathan, S.; Ison, M. G.; Liu, H.; Fang, D.; Shen, Y.
10.1101/2024.03.01.582176 — immunology — Posted on 2024-03-04
4618 Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate AVX/COVID-12 Activates T Cells and Is Recognized by Antibodies from COVID-19 Patients and Vaccinated
Torres-Flores, A.; Ontiveros-Padilla, L. A.; Madera-Sandoval, R. L.; Tepale-Segura, A.; Gajon-Martinez, J.; Rivera-Hernandez, T.; Ferat-Osorio, E. A.; Cerbulo-Vazquez, A.; Arriaga-Pizano, L. A.; Bonifaz, L.; Paz-De la Rosa, G.; Rojas-Martinez, O.; Suarez-Martinez, A.; Peralta-Sanchez, G.; Sarfati-Mizrahi, D.; Sun, W.; Chagoya-Cortes, H. E.; Palese, P.; Krammer, F.; Garcia-Sastre, A.; Lozano-Dubernard, B.; Lopez-Macias, C.
10.1101/2024.03.01.582987 — immunology — Posted on 2024-03-04
4619 B cell maturation restored ancestral germlines to control Omicron BA.2.86
Paciello, I.; Pierleoni, G.; Pantano, E.; Antonelli, G.; Pileri, P.; Maccari, G.; Cardamone, D.; Realini, G.; Perrone, F.; Neto, M. M.; Pozzessere, S.; Fabbiani, M.; Panza, F.; Rancan, I.; Tumbarello, M.; Montagnani, F.; Medini, D.; Maes, P.; Temperton, N. J.; Simon-Loriere, E.; Schwartz, O.; Rappuoli, R.; Andreano, E.
10.1101/2024.03.03.583187 — immunology — Posted on 2024-03-04
4620 Time-dependent enhancement of mRNA vaccines by 4-1BB costimulation
Sanchez, S.; Dangi, T.; Awakoaiye, B.; Irani, N.; Fourati, S.; Richner, J. M.; Penaloza-MacMaster, P.
10.1101/2024.03.01.582992 — immunology — Posted on 2024-03-04
4621 Proteome-scale tissue mapping using mass spectrometry based on label-free and multiplexed workflows
Kwon, Y.; Woo, J.; Yu, F.; Williams, S. M.; Markillie, L. M.; Moore, R. J.; Nakaysu, E. S.; Chen, J.; Campbell-Thompson, M.; Mathews, C. E.; Nesvizhskii, A. I.; Qian, W.-J.; Zhu, Y.
10.1101/2024.03.04.583367 — systems biology — Posted on 2024-03-04
4624 Molecular Speciation of Cyathostomins From Horses In Ireland
Byrne, O.; Gangotia, D.; Crowley, J.; Zintl, A.; Kiser, L.; McSweeney, D.; Lamb, B.-R.; O'Neill, F.; Dunne, S.; Boxall, O.; Walshe, N.; Mulcahy, G.
10.1101/2023.12.13.571572 — molecular biology — Posted on 2024-03-04
4626 Inflamed Natural Killer cells with adhesion defects are associated with a poor prognosis in Multiple Myeloma
Blanquart, E.; Ekren, R.; Rigaud, B.; Joubert, M.-V.; Baylot, V.; Daunes, H.; Cuisinier, M.; Villard, M.; Carrie, N.; Mazzotti, C.; Lucca, L. E.; Perrot, A.; Corre, J.; Walzer, T.; Avet-Loiseau, H.; Axisa, P.-P.; Martinet, L.
10.1101/2024.01.15.575654 — immunology — Posted on 2024-03-04
4629 HTLV-1 infected T cells cause bone loss via small extracellular vesicles
Pokhrel, N. K.; Panfil, A.; Habib, H.; Seeniraj, S.; Joseph, A.; Rauch, D.; Sprung, R.; Gilmore, P. E.; Zhang, Q.; Townsend, R. R.; Yu, L.; Yilmaz, A. S.; Aurora, R.; Park, W.; Ratner, L.; Weilbaecher, K. N.; Veis, D. J.
10.1101/2024.02.29.582779 — cancer biology — Posted on 2024-03-04
4630 Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis
Hsiao, H.-Y.; Cheng, C.-C.; Chou, Y.-T.; Kuo, C.-C.; Wang, W.-C.; Sampurna, B. P.; Wang, Y.-W.; Hsiao, C.-L.; Wu, J.-Y.; Lin, K.-H.; Yang, W.-Y.; Lin, Y.-H.; Gwee, K.-H.; Wang, H.-D.; Yuh, C.-H.
10.1101/2024.02.29.582877 — cancer biology — Posted on 2024-03-04
4631 Brain-wide neuronal circuit connectome of human glioblastoma
Sun, Y.; Wang, X.; Zhang, D. Y.; Zhang, Z.; Bhattarai, J. P.; Wang, Y.; Dong, W.; Zhang, F.; Park, K. H.; Galanaugh, J.; Sambangi, A.; Yang, Q.; Kim, S. H.; Wheeler, G.; Goncalves, T.; Wang, Q.; Geschwind, D.; Kawaguchi, R.; Wang, H.; Xu, F.; Binder, Z. A.; Chen, I. H.; Pai, E. L.-L.; Stone, S.; Nasrallah, M.; Christian, K. M.; Fuccillo, M.; O'Rourke, D. M.; Ma, M.; Ming, G.-l.; Song, H.
10.1101/2024.03.01.583047 — cancer biology — Posted on 2024-03-04
4632 Targeting GFPT2 to reinvigorate immunotherapy in EGFR-mutated NSCLC
Ao, L.; Jia, W.; Gong, Q.; Cui, J.; Wang, J.; Yu, Y.; Fu, C.; Li, H.; Wei, J.; Wang, R.; Wang, F.; Shang, X.; Li, Y.; Fang, S.; Wang, G.; Zhou, F.; Liu, J.
10.1101/2024.03.01.582888 — cancer biology — Posted on 2024-03-04
4633 Surface adhesion and membrane fluctuations influence the elastic modulus of extracellular vesicles
Stridfeldt, F.; Kylhammar, H.; Metem, P.; Pandey, V.; Agrawal, V.; Gorgens, A.; Mamand, D. R.; Gustafsson, O.; El Andaloussi, S.; Mitra, D.; Dev, A.
10.1101/2024.02.07.578591 — biophysics — Posted on 2024-03-04
4638 Healthy microbiome - moving towards functional interpretation
Zielinska, K.; Udekwu, K.; Rudnicki, W.; Frolova, A.; Kosciolek, T.; Labaj, P. P.
10.1101/2023.12.04.569909 — bioinformatics — Posted on 2024-03-04
4640 Genomic evidence reveals three sequential W-autosome fusions in Heliconius butterflies
Rueda-M, N.; Pardo-Diaz, C.; Montejo-Kovacevich, G.; McMillan, W. O.; Kozak, K. M.; Arias, C. F.; Ready, J.; McCarthy, S.; Durbin, R.; Jiggins, C. D.; Meier, J.; Salazar, C.
10.1101/2023.03.06.531374 — evolutionary biology — Posted on 2024-03-04
4642 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus
Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.
10.1101/2023.08.22.554078 — molecular biology — Posted on 2024-03-04
4643 Evaluation Of Suitability Analysis of Gangetic Water from Upper, Middle, And Lower Ganga Rivers
Balkrishna, A.; Singh, S.; Nagose, A.; Joshi, D.; Kannojia, K.; Taneja, S.; Saxena, A.; Arya, V.; Ghosh, S.
10.1101/2024.02.28.582642 — microbiology — Posted on 2024-03-04
4648 Activating soluble adenylyl cyclase protects mitochondria, rescues retinal ganglion cells, and ameliorates visual dysfunction caused by oxidative stress
Bastola, T.; Perkins, G. A.; Huu, V. A. N.; Ju, S.; Kim, K.-Y.; Shen, Z.; Skowronska-Krawczyk, D.; Weinreb, R. N.; Ju, W.-K.
10.1101/2024.03.04.583371 — neuroscience — Posted on 2024-03-04
4649 A Methodology for Specific Disruption of Microtubules in Dendritic Spines
Holland, E. D.; Miller, H. L.; Millette, M. M.; Taylor, R. J.; Drucker, G. L.; Dent, E. W.
10.1101/2024.03.04.583370 — neuroscience — Posted on 2024-03-04
4650 Functional Diversity of Dopamine Axons in Prefrontal Cortex During Classical Conditioning
Abe, K.; Kambe, Y.; Majima, K.; Hu, Z.; Ohtake, M.; Momennezhad, A.; Izumi, H.; Tanaka, T.; Matunis, A.; Stacy, E.; Itokazu, T.; Sato, T. R.; Sato, T. K.
10.1101/2023.08.23.554475 — neuroscience — Posted on 2024-03-04
4655 Anatomical and functional organization of cardiac fibers in the porcine cervical vagus nerve allows spatially selective efferent neuromodulation
Thompson, N.; Ravagli, E.; Mastitskaya, S.; Challita, R.; Hadaya, J.; Iacoviello, F.; Shah Idil, A.; Shearing, P. R.; Ajijola, O. A.; Ardell, J. L.; Shivkumar, K.; Holder, D.; Aristovich, K.
10.1101/2024.01.09.574861 — neuroscience — Posted on 2024-03-04
4656 Neuronal Network Dynamics in the Posterodorsal Amygdala: Shaping Reproductive Hormone Pulsatility
Nechyporenko, K.; Voliotis, M.; Li, X. F.; Hollings, O.; Ivanova, D.; Walker, J. J.; O'Byrne, K. T.; Tsaneva-Atanasova, K.
10.1101/2024.01.21.574304 — neuroscience — Posted on 2024-03-04
4657 Expanding the genetic toolbox for the obligate human pathogen Streptococcus pyogenes
Lautenschlaeger, N.; Schmidt, K.; Schiffer, C.; Wulff, T. F.; Hahnke, K.; Finstermeier, K.; Mansour, M.; Elsholz, A. K. W.; Charpentier, E.
10.1101/2024.03.04.582890 — synthetic biology — Posted on 2024-03-04
4659 Impact of alternative splicing on Arabidopsis proteome
Reyes, A. V.; Shrestha, R.; Grismer, T. S.; Byun, D.; Xu, S.
10.1101/2024.02.29.582853 — plant biology — Posted on 2024-03-04
4662 Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells
Tanjala, A. C.; Jiang, J. X.; Eckford, P. D. W.; Ramjeesingh, M.; Li, C.; Huan, L. J.; Langeveld, G.; Townsend, C.; Paone, D.; Busch Petersen, J.; Pekhletski, R.; Tang, L.; Raju, V.; Rowe, S. M.; Bear, C.
10.1101/2024.03.01.582742 — physiology — Posted on 2024-03-04
4664 Effects of input image size on the accuracy of fish identification using deep learning.
Iwahara, Y.; Shibata, Y.; Manano, M.; Nishino, T.; Kariya, R.; Yaemori, H.
10.1101/2024.03.01.582886 — ecology — Posted on 2024-03-04
4670 ADP-dependent platelet activation is required for thrombus formation during a long-distance flight
Tour,, J.; Carminita, E.; Bruzzese, L.; Crescence, L.; Adjiriou, N.; Guieu, R.; Dubois, C.; Panicot-Dubois, L.
10.1101/2024.03.01.582882 — pathology — Posted on 2024-03-04
4671 Scvi-hub: an actionable repository for model-driven single cell analysis
Ergen, C.; Pour Amiri, V. V.; Kim, M.; Streets, A.; Gayoso, A.; Yosef, N.
10.1101/2024.03.01.582887 — bioinformatics — Posted on 2024-03-04
4676 PI3K-dependant reprogramming of hexokinase isoforms controls glucose metabolism and functional responses of B lymphocytes
Paradoski, B.; Hou, S.; Mejia, E.; Adefemi-Olayinka, F.; Fowke, D.; Hatch, G. M.; Saleem, A.; Banerji, V.; Hay, N.; Zeng, H.; Marshall, A.
10.1101/2024.02.29.582554 — immunology — Posted on 2024-03-04
4678 Social transmission of inflammation in mice
Quintana, S. C.; da Rosa, P. B.; Shionoya, K.; Blomqvist, A.; Engblom, D.
10.1101/2024.02.29.582723 — neuroscience — Posted on 2024-03-04
4680 Machine learning-based spike sorting reveals how subneuronal concentrations of monomeric Tau cause a loss in excitatory postsynaptic currents in hippocampal neurons
Brockhoff, M.; Träuble, J.; Middya, S.; Fuchsberger, T.; Fernandez-Villegas, A.; Stephens, A. D.; Robbins, M.; Dai, W.; Haider, B.; Vora, S.; Läubli, N. F.; Kaminski, C. F.; Malliaras, G. G.; Paulsen, O.; Schierle, G. S. K.
10.1101/2024.02.29.582792 — neuroscience — Posted on 2024-03-04
4681 Prostaglandin D2 synthase controls Schwann cells metabolism
Trimarco, A.; Audano, M.; La Marca, R.; Cariello, M.; Falco, M.; Pedretti, S.; Imperato, G.; Cestaro, A.; Podini, P.; Dina, G.; Quattrini, A.; Massimino, L.; Caruso, D.; Mitro, N.; Taveggia, C.
10.1101/2024.02.29.582775 — neuroscience — Posted on 2024-03-04
4683 Measuring instability in chronic human intracortical neural recordings towards stable, long-term brain-computer interfaces
Pun, T. K.; Khoshnevis, M.; Hosman, T.; Wilson, G. H.; Kapitonava, A.; Kamdar, F.; Henderson, J. M.; Simeral, J. D.; Vargas-Irwin, C. E.; Harrison, M. T.; Hochberg, L. R.
10.1101/2024.02.29.582733 — neuroscience — Posted on 2024-03-04
4687 Proteomic profiling of IDH-wildtype Glioblastoma Tissue and Serum uncovers prognostic Subtypes and Marker Candidates
Werner, T.; Schaefer, A.; Hennes, M.; Cosenza Contreras, M.; Espadas, G.; Sabido, E.; Cook, L.; Pagenstecher, A.; Pinter, N.; Feilen, T.; Grote, A.; Nimsky, C.; Bartsch, J. W.; Schilling, O.
10.1101/2024.02.29.582688 — cancer biology — Posted on 2024-03-04
4689 High-resolution fleezers reveal duplex opening and stepwise assembly by an oligomer of the DEAD-box helicase Ded1p
Patrick, E. M.; Yadav, R.; Senanayake, K.; Cotter, K.; Putnam, A. A.; Jankowsky, E.; Comstock, M. J.
10.1101/2024.02.29.582829 — biophysics — Posted on 2024-03-04
4690 MASCARA: coexpression analysis in data from designed experiments
White, F.; Heintz-Buschart, A.; Dong, L.; Bouwmeester, H.; Westerhuis, J.; Smilde, A.
10.1101/2024.02.29.582876 — bioinformatics — Posted on 2024-03-04
4692 Segmentation error aware clustering for highly multiplexed imaging
Lee, Y.; Chen, E. L. Y.; Chan, D. C. H.; Dinesh, A.; Afiuni-Zadeh, S.; Klamann, C.; Selega, A.; Mrkonjic, M.; Jackson, H. W.; Campbell, K. R.
10.1101/2024.02.29.582827 — bioinformatics — Posted on 2024-03-04
4695 Secondary microglia formation center in the human fetal brain
Song, C.; Chen, X.; Ji, R.; Liu, Y.; Zhang, L.; Gao, L.; He, Q.; Ma, L.; saiyin, H.
10.1101/2024.02.29.582659 — neuroscience — Posted on 2024-03-04
4696 Network Analysis of the Cerebrospinal Fluid Proteome Reveals Shared and Unique Differences Between Sporadic and Familial Forms of Amyotrophic Lateral Sclerosis
Trautwig, A. N.; Fox, E. J.; Dammer, E. B.; Shantaraman, A.; Ping, L.; Duong, D. M.; Levey, A. I.; Lah, J. J.; Fournier, C. N.; McEachin, Z. T.; Glass, J. D.; Seyfried, N. T.
10.1101/2024.02.29.582840 — neuroscience — Posted on 2024-03-04
4698 Robotic Laser Tissue Soldering for Damage-free Soft Tissue Fusion Guided by Fluorescent Nanothermometry
Cipolato, O.; Leuthold, T.; Zaech, M.; Maennel, G.; Aegerter, S.; Sciascia, C.; Jessernig, A.; Sarcevic, S.; Rosendorf, J.; Liska, V.; Kundrat, D.; Quidant, R.; Herrmann, I. K.
10.1101/2024.02.29.582843 — bioengineering — Posted on 2024-03-04
4700 Regulation of immune signal integration and memory by inflammation-induced chromosome conformation
Daniel, B.; Chen, A. Y.; Sandor, K.; Zhang, W.; Miao, Z.; Lareau, C. A.; Yost, K. E.; Chang, H.; Satpathy, A.
10.1101/2024.02.29.582872 — genomics — Posted on 2024-03-04
4702 A novel method for fine-scale retrospective isotope analysis in mammals using eye lenses
Miura, K.; Matsubayashi, J.; Yoshimizu, C.; Takafumi, H.; Shirane, Y.; Mano, T.; Tsuruga, H.; Tayasu, I.
10.1101/2024.02.29.582866 — ecology — Posted on 2024-03-04
4703 Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators
Bonilla, G.; Morris, A.; Kundu, S.; Ducasse, A.; Jeffries, N. E.; Chetal, K.; Yvanovich, E. E.; Barghout, R.; Scadden, D.; Mansour, M.; Kingston, R. E.; Sykes, D. B.; Mercier, F. E.; Sadreyev, R. I.
10.1101/2024.02.29.582846 — molecular biology — Posted on 2024-03-04
4705 Gene expression and eQTL analysis reflect the heterogeneity in the inflammatory status of the duodenal epithelial lining in coeliac disease
Ramirez-Sanchez, A. D.; Zühlke, S.; Aguirre-Gamboa, R.; Vochteloo, M.; Franke, L.; Lundin, K. E. A.; Withoff, S.; Jonkers, I. H.
10.1101/2024.02.29.582756 — immunology — Posted on 2024-03-04
4706 Activation of locus coeruleus noradrenergic neuronsrapidly drives homeostatic sleep pressure
Silverman, D.; Chen, C.; Chang, S.; Bui, L.; Zhang, Y.; Raghavan, R.; Jiang, A.; Darmohray, D.; Sima, J.; Ding, X.; Li, B.; Ma, C.; Dan, Y.
10.1101/2024.02.29.582852 — neuroscience — Posted on 2024-03-04
4707 Brain orchestra under spontaneous conditions: Identifying communication modules from the functional architecture of area V1
Papadopouli, M.; Koniotakis, E.; Smyrnakis, I.; Savaglio, M. A.; Psilou, E.; Brozi, C.; Palagina, G.; Smirnakis, S. M.
10.1101/2024.02.29.582364 — neuroscience — Posted on 2024-03-04
4709 PKHD1L1 is required for stereocilia bundle maintenance, prolonged hearing function and enhanced resilience to noise exposure.
strelkova, O. S.; Osgood, R. T.; Tian, C. J.; Zhang, X.; Hale, E.; De-la-Torre, P.; Hathaway, D. M.; Indzhykulian, A. A.
10.1101/2024.02.29.582786 — neuroscience — Posted on 2024-03-04
4710 Low intensity repetitive transcranial magnetic stimulation enhances remyelination by newborn and surviving oligodendrocytes in the cuprizone model of toxic demyelination
Nguyen, P. T.; Makowiecki, K.; Lewis, T. S.; Fortune, A.; Clutterbuck, M.; Reale, L.; Taylor, B. V.; Rodger, J.; Cullen, C. L.; Young, K.
10.1101/2024.02.29.582855 — neuroscience — Posted on 2024-03-04
4711 Insulin-mediated suppression of fatty acid release predicts whole-body insulin resistance of glucose uptake and skeletal muscle insulin receptor activation
Schleh, M.; Ryan, B.; Ahn, C.; Ludzki, A.; Van Pelt, D.; Pitchford, L.; Chugh, O.; Luker, A. T.; Luker, K. E.; Samovski, D.; Abumrad, N.; Burant, C.; Horowitz, J.
10.1101/2024.02.29.582589 — physiology — Posted on 2024-03-04
4713 Sex differences in early human fetal brain development
Buonocore, F.; Suntharalingham, J. P.; Ogunbiyi, O.; Jones, A.; Moreno, N.; Niola, P.; Brooks, T.; Solanky, N.; Dattani, M. T.; del Valle, I.; Achermann, J. C.
10.1101/2024.03.04.583285 — developmental biology — Posted on 2024-03-04
4714 Increasing the vitamin C transporter SVCT2 in microglia improves synaptic plasticity and restrains memory impairments in Alzheimer's disease models
Portugal, C. C.; Santos, E. C. S.; Pacheco, A. M.; Costa-Pinto, S.; Almeida, T. O.; Tedim-Moreira, J.; Gavin, D.; Canedo, T.; Oliveira, F.; Summavielle, T.; Vaz, S. H.; Socodato, R.; Relvas, J. B.
10.1101/2024.02.29.582679 — neuroscience — Posted on 2024-03-04
4717 Correlation measures in metagenomic data: the blessing of dimensionality
Fuschi, A.; Merlotti, A.; Tran, D. B.; Nguyen, H.; Weinstock, G.; Remondini, D.
10.1101/2024.02.29.582875 — systems biology — Posted on 2024-03-04
4719 Self-Supervised Learning Reveals Clinically Relevant Histomorphological Patterns for Therapeutic Strategies in Colon Cancer
Liu, B.; Polack, M.; Coudray, N.; Quiros, A. C.; Sakellaropoulos, T.; Crobach, A. S. L. P.; van Krieken, J. H. J. M.; Yuan, K.; Tollenaar, R. A. E. M.; Mesker, W. E.; Tsirigos, A.
10.1101/2024.02.26.582106 — bioinformatics — Posted on 2024-03-04
4722 Strategies for Inducing and Validating Zinc Deficiency and Zinc Repletion
Wenegieme, T.-Y.; Elased, D.; Rockwood, J.; Hasrat, K.; McMichael, K.; Marshall, A.; Neikirk, K.; Kirabo, A.; Elased, K.; Hinton, A.; Williams, C.
10.1101/2024.02.28.582542 — physiology — Posted on 2024-03-04
4723 Identification of bazedoxifene for the treatment of LGMD R2 by high throughput screening.
Bruge, C.; Bourg, N.; PELLIER, E.; Tournois, J.; Polentes, J.; BENABIDES, M.; Grossi, N.; Bigot, A.; Brureau, A.; Richard, I.; Nissan, X.
10.1101/2024.02.28.582550 — pharmacology and toxicology — Posted on 2024-03-04
4724 Tumor-microvessel on-a-chip reveals sequential intravasation cascade of cancer cell clusters
Ikeda, Y.; Suehiro, J.-i.; Oshima, H.; Kok, S. Y.; Takahashi, K.; Sakurai, H.; Watabe, T.; Oshima, M.; Matsunaga, Y. T.
10.1101/2024.02.28.582606 — cancer biology — Posted on 2024-03-04
4726 The transcriptomic landscape of monosomy X (45,X) during early human fetal and placental development
Suntharalingham, J. P.; del Valle, I.; Buonocore, F.; McGlacken-Byrne, S. M.; Brooks, T.; Ogunbiyi, O. K.; Liptrot, D.; Dunton, N.; Madhan, G. K.; Metcalfe, K.; Nel, L.; Marshall, A. R.; Ishida, M.; Sebire, N. J.; Moore, G. E.; Crespo, B.; Solanky, N.; Conway, G. S.; Achermann, J. C.
10.1101/2024.03.01.582942 — genetics — Posted on 2024-03-04
4727 Molecular Signatures of Normal Pressure Hydrocephalus: A Large-scale Proteomic Analysis of Cerebrospinal Fluid
Kamalian, A.; Shirzadeh Barough, S.; Ho, S. G.; Albert, M.; Luciano, M. G.; Yasar, S.; Moghekar, A.
10.1101/2024.03.01.583014 — neuroscience — Posted on 2024-03-04
4732 CAM evolution is associated with gene family expansion in an explosive bromeliad radiation
Groot Crego, C.; Hess, J.; Yardeni, G.; de la Harpe, M.; Priemer, C.; Beclin, F.; Cauz-Santos, L. A.; Saadain, S.; Temsch, E. M.; Weiss-Schneeweiss, H.; Barfuss, M. H. J.; Till, W.; Weckwerth, W.; Heyduk, K.; Lexer, C.; Paun, O.; Leroy, T.
10.1101/2023.02.01.526631 — evolutionary biology — Posted on 2024-03-04
4735 Genotypic and phenotypic characterization of a nosocomial outbreak of Candida auris in Spain during five years
Mulet, J. V.; Cancino-Munoz, I. N.; Salvador-Garcia, C.; Tormo-Palop, N.; Guna, R.; Gonzalez-Candelas, F.; Gimeno-Cardona, C.
10.1101/2024.03.01.582904 — microbiology — Posted on 2024-03-04
4737 Exposure to HIV alters the composition of maternal microchimeric T cells in infants
Armistead, B.; Peters, Q.; Houck, J.; Carlson, M.; Balle, C.; Mulugeta, N.; Gray, C.; Jaspan, H. B.; Harrington, W. E.
10.1101/2024.03.01.583002 — immunology — Posted on 2024-03-04
4739 Using a Forster-resonance energy transfer (FRET)-based detection system (FedEcs) to monitor nanoparticle cargo delivery to the brain
Khalin, I.; Adarsh, N.; Schifferer, M.; Wehn, A.; Boide-Trujillo, V. J.; Mamrak, U.; Shrouder, J. J.; Misgeld, T. J.; Filser, S.; Klymchenko, A. S.; Plesnila, N.
10.1101/2024.02.28.582471 — neuroscience — Posted on 2024-03-04
4742 Prediction of brain age in individuals with and at risk for alcohol use disorder using brain morphological features
Kamarajan, C.; Ardekani, B. A.; Pandey, A. K.; Meyers, J. L.; Chorlian, D. B.; Kinreich, S.; Pandey, G.; Richard, C.; de Viteri, S. S.; Kuang, W.; Porjesz, B.
10.1101/2024.03.01.582844 — neuroscience — Posted on 2024-03-04
4746 Generative artificial intelligence performs rudimentary structural biology modelling
Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.
10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-03-04
4747 De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments
Eloff, K.; Kalogeropoulos, K.; Morell, O.; Mabona, A.; Berg Jespersen, J.; Williams, W.; van Beljouw, S. P. B.; Skwark, M.; Hougaard Laustsen, A.; Brouns, S. J. J.; Ljungars, A.; Schoof, E. M.; Van Goey, J.; auf dem Keller, U.; Beguir, K.; Lopez Carranza, N.; Jenkins, T. P.
10.1101/2023.08.30.555055 — bioinformatics — Posted on 2024-03-04
4748 Chromosome-level genome assembly of milk thistle (Silybum marianum (L.) Gaertn.)
Kim, K. D.; Shim, J.; Hwang, J.-H.; Kim, D.; El baidouri, M.; Park, S.; Song, J.; Yu, Y.; Lee, K.; Ahn, B.-O.; Hong, S. Y.; Chin, J. H.
10.1101/2024.02.29.582772 — genomics — Posted on 2024-03-04
4750 The dual role of a highly structured RNA (the S fragment) in the replication of foot-and-mouth disease virus.
Ward, J. C.; Lasecka-Dykes, L.; Dobson, S. J.; Gold, S.; Kingston, N. J.; Herod, M. R.; King, D. P.; Tuthill, T. J.; Rowlands, D. J.; Stonehouse, N. J.
10.1101/2023.04.26.538422 — molecular biology — Posted on 2024-03-04
4752 Neuronal lysosome transfer to oligodendrocyte precursor cells: a novel mechanism of neuron-glia communication and its role in neurodegenerative disease
Fang, L.-P.; Lin, C.-H.; Medlej, Y.; Zhao, R.; Chang, H.-F.; Su, Y.; Zhao, N.; Gobbo, D.; Guo, Q.; Wyatt, A.; Wahl, V.; Boehm, U.; Huang, W.; Lauterbach, M. A.; Yi, C.; Niu, J.; Scheller, A.; Kirchhoff, F.; Bai, X.
10.1101/2024.03.03.583173 — neuroscience — Posted on 2024-03-04
4756 Dynamics of morphogen source formation in a growing tissue
Ho, R. D. J. G.; Kishi, K.; Majka, M.; Kicheva, A.; Zagorski, M.
10.1101/2024.03.01.582751 — systems biology — Posted on 2024-03-03
4757 Multi-condition and multi-modal temporal profile inference during mouse embryonic development
Zhang, R.; Qiu, C.; Filippova, G.; Li, G.; Shendure, J.; Vert, J.-P.; Deng, X.; Disteche, C. M.; Noble, W. S.
10.1101/2024.03.03.583179 — bioinformatics — Posted on 2024-03-04
4760 Non-linear transcriptional responses to gradual modulation of transcription factor dosage
Domingo, J.; Minaeva, M.; Morris, J. A.; Ziosi, M.; Sanjana, N. E.; Lappalainen, T.
10.1101/2024.03.01.582837 — genomics — Posted on 2024-03-04
4764 The potential of undersown species identity vs. diversity to manage disease in crops
Cappelli, S. L.; Domeignoz Horta, L. A.; Gerin, S.; Heinonsalo, J.; Lohila, A.; Raveala, K.; Schmid, B.; Shrestha, R.; Tiusanen, M. J.; Thitz, P.; Laine, A.-L.
10.1101/2024.02.29.582760 — ecology — Posted on 2024-03-03
4766 Low protein diet protects liver function upon Salmonella infection by metabolic reprogramming of macrophages
Wojtowicz, E. E.; Hampton, K.; Moreno-Gonzalez, M.; Utting, C. L.; Lan, Y.; Ruiz, P.; Beasy, G.; Bone, C.; Hellmich, C.; Maynard, R.; Acton, L.; Telatin, A.; Kingsley, R. A.; Macaulay, I. C.; Rushworth, S. A.; Beraza, N.
10.1101/2024.03.01.582753 — immunology — Posted on 2024-03-03
4767 Cell-type specific effects of Fusarium mycotoxins on primary neuronal and astroglial cells
Szentgyörgyi, V.; Bencsik, N.; Micska, B.; Ratkai, A.; Schlett, K.; Tarnok, K.
10.1101/2024.02.29.582764 — neuroscience — Posted on 2024-03-03
4768 Direct retino-iridal projections and intrinsic iris contraction mediate the pupillary light reflex in early vertebrates
Jimenez-Lopez, C.; Rivas-Ramirez, P.; Barandela, M.; Nunez-Gonzalez, C.; Megias, M.; Perez-Fernandez, J.
10.1101/2024.02.29.582767 — neuroscience — Posted on 2024-03-03
4772 Systematics of the fleshy-fruited Sonerileae (Melastomataceae)
Quakenbush, J. P.; Chen, L.; Penneys, D. S.; Barkman, T. J.; Liu, Y.; Yakandawala, D.; Libalah, M. C. V. E.; Kadereit, G.
10.1101/2024.03.03.582138 — plant biology — Posted on 2024-03-03
4773 Trabectedin Enhances Oncolytic Virotherapy by Reducing Barriers to Virus Spread and Cytotoxic Immunity in Preclinical Pediatric Bone Sarcoma
Ringwalt, E. M.; Currier, M. A.; Glaspell, A. M.; Chen, C.-Y.; Cannon, M. V.; Cam, M.; Gross, A. C.; Gust, M.; Wang, P.-Y.; Boon, L.; Biederman, L. E.; Schwarz, E.; Rajappa, P.; Lee, D. A.; Mardis, E. R.; Carson, W. E.; Roberts, R. D.; Cripe, T. P.
10.1101/2024.03.02.582994 — cancer biology — Posted on 2024-03-03
4776 The Updated Mouse Universal Genotyping Array Bioinformatic Pipeline Improves Genetic QC in Laboratory Mice
Blanchard, M. W.; Sigmon, J. S.; Brennan, J.; Ahulamibe, C.; Allen, M. E.; Baric, R. S.; Bell, T. A.; Farrington, J.; Ciavatta, D.; Cruz Cisneros, M.; Drushal, M.; Ferris, M. T.; Fry, R.; Gaines, C.; Gu, B.; Heise, M. T.; Hodges, R. A.; Kafri, T.; Lynch, R.; Magnuson, T.; Miller, D.; Murphy, C. E. Y.; Nguyen, D. T.; Noll, K. E.; Proulx, M.; Sassetti, C.; Shaw, G. D.; Simon, J. M.; Smith, C.; Styblo, M.; Tarantino, L.; Woo, J.; Pardo-Manuel de Villena, F.
10.1101/2024.02.29.582794 — genetics — Posted on 2024-03-03
4781 Beyond Kaftrio: mechanistic insights to maximize N1303K-CFTR rescue
Pranke, I.; Capurro, V.; Chevalier, B.; Pesce, E.; Tomati, V.; Pastorino, C.; Hatton, A.; Urien, S.; Lena, M.; Dreano, E.; Bocciardi, R.; Zara, F.; Pantano, S.; Terlizzi, V.; Lucanto, C.; Costa, S.; Claut, L.; Dacco, V.; Poli, P.; Maschio, M.; Fabrizzi, B.; Caporelli, N.; Cipolli, M.; Volpi, S.; Jung, V.; Roger, K.; Chedevergne, F.; Cosson, L.; Macey, J.; LeBihan, J.; Weiss, L.; Grenet, D.; LeClainche Viala, L.; Douvry, B.; Ravoninjatovo, B.; Audousset, C.; Tatopoulos, A.; Richaud Thiriez, B.; Baravalle, M.; Thouvenin, G.; Labbe, G.; Mittaine, M.; Reix, P.; Durieu, I.; Mankikian, J.; Bui, S.;
10.1101/2024.02.29.582514 — physiology — Posted on 2024-03-03
4782 Comparing cellular response to two radiation treatments based on key features visualization
Arsenteva, P.; Guipaud, O.; Paget, V.; Dos Santos, M.; Tarlet, G.; Milliat, F.; Cardot, H.; Benadjaoud, M. A.
10.1101/2024.02.29.582706 — bioinformatics — Posted on 2024-03-03
4784 Unveiling the Power of High-Dimensional Cytometry Data with cyCONDOR
Kroeger, C.; Mueller, S.; Leidner, J.; Kroeber, T.; Warnat-Herresthal, S.; Spintge, J. B.; Zajac, T.; Frolov, A.; Carraro, C.; Puccio, S.; Schultze, J. L.; Pecht, T.; Beyer, M. D.; Bonaguro, L.
10.1101/2024.02.29.582727 — bioinformatics — Posted on 2024-03-03
4791 Predicting Attentional Focus: Heartbeat-Evoked Responses and Brain Dynamics During Interoceptive and Exteroceptive Information Processing
Flo, E.; Belloli, L.; Cabana, A.; Ruyan-Belabbas, A.; Jodaitis, L.; Valente, M.; Rohaut, B.; Naccache, L.; Rosanova, M.; Comanducci, A.; Andrillon, T.; Sitt, J.
10.1101/2023.11.03.565584 — neuroscience — Posted on 2024-03-03
4793 Brassinosteroid and gibberellin signaling are required for Tomato internode elongation in response to low red: far-red light
Li, L.; Helming, T.; Wonder, J.; van Asselt, G.; Pantazopoulou, C. K.; van de Kaa, Y. T. R.; Kohlen, W.; Pierik, R.; Kajala, K.
10.1101/2024.02.29.582690 — plant biology — Posted on 2024-03-03
4795 Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma
Motahari, Z.; Lepe, J. L.; Bautista, M. R.; Hoerig, C.; Plant-Fox, A. S.; Das, B.; Fowler, C. D.; Magge, S. N.; Bota, D. A.
10.1101/2024.02.29.582709 — cancer biology — Posted on 2024-03-03
4802 SMA Type II Skeletal Muscle Treated with Nusinersen shows SMN Restoration but Mitochondrial Deficiency.
Grandi, F. C.; Astord, S.; Gidaja, E.; Pezet, S.; Mazzucchi, S.; Chapart, M.; Vasseur, S.; Mamchaoui, K.; Smeriglio, P.
10.1101/2024.02.29.582680 — genetics — Posted on 2024-03-03
4803 TabHLH27 orchestrates root growth and drought tolerance to enhance water use efficiency in wheat
Wang, D.; Zhang, X.; Cao, Y.; Batool, A.; Xu, Y.; Qiao, Y.; Li, Y.; Wang, H.; Lin, X.; Bie, X.; Zhang, X.; Jing, R.; Dong, B.; Tong, Y.; Teng, W.; Liu, X.; Xiao, J.
10.1101/2024.02.29.582695 — genetics — Posted on 2024-03-03
4804 Decoding the Baltic Sea's Past and Present: A simple Molecular Index for Ecosystem Assessment
Schmidt, A.; Roman, J.; Andren, E.; Kremp, A.; Kaiser, J.; Arz, H. W.; Dellwig, O.; Balint, M.; Epp, L. S.
10.1101/2024.02.29.582456 — ecology — Posted on 2024-03-03
4805 Depletion of essential GroEL protein in Escherichia coli using Clp-Interacting Peptidic Protein Erasers (CLIPPERs)
Izert-Nowakowska, M. A.; Klimecka, M. M.; Antosiewicz, A.; Wroblewski, K.; Bandyra, K. J.; Goral, T. K.; Kmiecik, S.; Serwa, R. A.; Gorna, M. W.
10.1101/2024.02.29.582761 — molecular biology — Posted on 2024-03-03
4809 Yellow Fever Emergence: Role of Heterologous Flavivirus Immunity in Preventing Urban Transmission
Shinde, D. P.; Plante, J. A.; Scharton, D.; Mitchel, B.; Walker, J.; Azar, S. R.; Kroon-Campos, R.; Sacchetto, L. A.; Drumond, B. P.; Vasilakis, N.; Plante, K. S.; Weaver, S. C.
10.1101/2024.03.03.583168 — microbiology — Posted on 2024-03-03
4810 Sequential Transcriptional Programs of Tissue Residency Drive Human Uterine NK Cell Development
Greene, M. E.; Asiimwe, R.; Wright, E.; Bell, M.; Epstein, D.; Yates, S. D.; Knott, B.; Fry, S.; Clevenger, S.; Locke, J.; Little, S. C.; Richter, H.; Freud, A. G.; Porrett, P. M.
10.1101/2024.02.29.582684 — immunology — Posted on 2024-03-03
4811 The Molecular Landscape of Cellular Metal Ion Biology
Aulakh, S. K.; Lemke, O.; Szyrwiel, L.; Kamrad, S.; Chen, Y.; Hartl, J.; Muelleder, M.; Nielsen, J.; Ralser, M.
10.1101/2024.02.29.582718 — systems biology — Posted on 2024-03-03
4812 Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation
Tian, X.; Zhang, L.; Tang, Y.; Xiang, G.; Wang, Z.; Zhu, P.; Yu, S.; Jiang, F.; Wang, S.; Wang, J.; Dai, Y.; Zhang, D.; Wang, J.; Liu, H.; Weng, X.; Wang, S.; Tan, Y.; Chen, Z.; Chen, S.; Liu, F.
10.1101/2024.02.29.582681 — cancer biology — Posted on 2024-03-03
4813 SEGUID v2: Extending SEGUID checksums for circular, linear, single- and double-stranded biological sequences
Pereira, H.; Silva, P. C.; Davis, W. M.; Abraham, L.; Babnigg, G.; Bengtsson, H.; Johansson, B.
10.1101/2024.02.28.582384 — bioinformatics — Posted on 2024-03-03
4816 The widely used cymoxanil fungicide impairs respiration in Saccharomyces cerevisiae via cytochrome c oxidase inhibition
Mendes, F.; Pereira, C.; Vieira, T.; Pinto, M.; Castro, B.; Sousa, S.; Sousa, M. J.; Devin, A.; Chaves, S.
10.1101/2024.02.29.582674 — biochemistry — Posted on 2024-03-03
4817 Testing the mettle of METAL: A comparison of phylogenomic methods using a challenging but well-resolved phylogeny
Braun, E. L.; Oliveros, C. H.; White Carreiro, N. D.; Zhao, M.; Glenn, T. C.; Brumfield, R. T.; Braun, M. J.; Kimball, R. T.; Faircloth, B. C.
10.1101/2024.02.28.582627 — evolutionary biology — Posted on 2024-03-03
4818 Understanding the effects of oxytocin receptor variants on OXT-OXT receptor binding: A mathematical model
Dubey, P.; Fang, Y.; Tukei, K. L.; Kuila, S.; Liu, X.; Sahota, A.; Frolova, A. I.; Reinl, E. L.; Malik, M.; England, S. K.; Imoukhuede, P. I.
10.1101/2024.02.28.582600 — systems biology — Posted on 2024-03-03
4821 Suppressing mortality and curbing cellular damage by targeting VHL
Jiang, W.; Cao, Y.; Xue, Y.; Ji, Y.; Winer, B. Y.; Zhang, M.; Singhal, N. S.; Pierce, J.; Chen, S.; Ma, D. K.
10.1101/2024.02.28.582664 — physiology — Posted on 2024-03-03
4824 Loss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis
Richter, C. E.; Raghunath, A.; Griffin, M. S.; Yaman, M.; Arruda, V. R.; Samelson-Jones, B. J.; Shavit, J.
10.1101/2024.02.28.582609 — genetics — Posted on 2024-03-03
4825 In silico identification of putative causal genetic variants
He, Z.; Chu, B.; Yang, J.; Gu, J.; Chen, Z.; Liu, L.; Morrison, T.; Belloy, M. E.; Qi, X.; Hejazi, N.; Mathur, M.; Le Guen, Y.; Tang, H.; Hastie, T.; Ionita-laza, I.; Sabatti, C.; Candes, E.
10.1101/2024.02.28.582621 — genetics — Posted on 2024-03-03
4828 LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3
Zheng, N.; Jaffery, R.; Guerrero, A.; Hou, J.; Pan, Y.; Zhou, F.; Chen, S.; Xu, C.; Egan, N. A.; Bohat, R.; Chen, K.; Schwarzschild, M. A.; Chen, X.; Peng, W.
10.1101/2024.02.28.582561 — immunology — Posted on 2024-03-03
4829 Comparison of Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations
Lee, Y. J.; Syed, K.; Busquets, O.; Li, H.; Dunnack, J.; Sahagun, A.; Bateup, H.; Soldner, F.; Hockemeyer, D.; Rio, D.
10.1101/2024.02.28.582420 — neuroscience — Posted on 2024-03-03
4830 Effects of noncanonical genomic imprinting in monoaminergic pathways on the regulation of social behaviors
O'Leary, E. M.; Rahman, S. J.; Tamas, A. L.; Huang, T.; Dweydari, M.; Eggleston, R. L.; Meling, D. D.; Bonthuis, P. J.
10.1101/2024.02.28.582619 — neuroscience — Posted on 2024-03-03
4831 Corticothalamic modelling of sleep neurophysiology with applications to mobile EEG
Morshedzadeh, T.; Kadak, K.; Bastiaens, S. P.; Oveisi, M. P.; Momi, D.; Wang, Z.; Harita, S.; Abou Jaude, M.; Aimone, C. A.; Mann, S.; Hill, S. L.; Griffiths, J. D.
10.1101/2024.02.28.582655 — neuroscience — Posted on 2024-03-03
4832 Two-photon imaging of excitatory and inhibitory neural response to infrared neural stimulation
Fu, P.; Liu, Y.; Zhu, L.; Wang, M.; Yu, Y.; Yang, F.; Zhang, W.; Zhang, H.; Shoham, S.; Roe, A. W.; Xi, W.
10.1101/2024.02.28.582632 — neuroscience — Posted on 2024-03-03
4833 Enhanced intracranial aneurysm development in a rat model of polycystic kidney disease.
Cayron, A. F.; Morel, S.; Azam, M.; Haemmerli, J.; Aoki, T.; Bijlenga, P.; Allemann, E.; Kwak, B. R.
10.1101/2024.02.28.582650 — pathology — Posted on 2024-03-03
4834 Direct measurement of RNA Polymerase II hypertranscription in cancer FFPE samples
Henikoff, S.; Henikoff, J. G.; Paranal, R. M.; Greene, J. E.; Russell, Z. R.; Szulzewsky, F.; Kugel, S.; Holland, E. C.; Ahmad, K.
10.1101/2024.02.28.582647 — cancer biology — Posted on 2024-03-03
4836 Conformational Ensembles Reveal the Origins of Serine Protease Catalysis
Du, S.; Kretsch, R. C.; Parres-Gold, J.; Pieri, E.; Cruzeiro, V. W. D.; Zhu, M.; Pinney, M. M.; Yabukarski, F.; Schwans, J. P.; Martinez, T. J.; Herschlag, D.
10.1101/2024.02.28.582624 — biophysics — Posted on 2024-03-03
4844 Systems genetics approach uncovers associations between host amylase locus, gut microbiome and metabolic traits in hyperlipidemic mice
Zhang, Q.; Hutchison, E. R.; Pan, C.; Warren, M. F.; Keller, M. P.; Attie, A. D.; Lusis, A. J.; Rey, F. E.
10.1101/2024.02.28.582610 — genetics — Posted on 2024-03-03
4845 Metabolic Deficiencies Underlie Plasmacytoid Dendritic Cell Exhaustion After Viral Infection
Greene, T. T.; Jo, Y.; Macal, M.; Fang, Z.; Khatri, F. S.; Codrington, A. L.; Kazane, K. R.; Chiale, C.; Akbulut, E.; Swaminathan, S.; Fujita, Y.; Fitzgerald-Bocarsly, P.; Cordes, T.; Metallo, C.; Scott, D. A.; Zuniga, E. I.
10.1101/2024.02.28.582551 — immunology — Posted on 2024-03-03
4849 Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating JMJD3
Saiioum, Z.; Dauner, K.; Li, Y.-f.; Verma, N.; Almendro-Vedia, V.; VALDIVIESO GONZALEZ, D.; Zhang, D. J.; Nakka, K.; McDonald, J.; Sorisky, A.; Song, B.-L.; Lopez Montero, I.; Luo, J.; Dilworth, J.; Zha, X.
10.1101/2023.01.09.523264 — biochemistry — Posted on 2024-03-03
4850 Biotic and abiotic drivers of ecosystem functioning differ between a temperate and a tropical region
van Dijk, L. J. A.; Miraldo, A.; Raharinjanahary, D.; Rajoelison, E. T.; Fisher, B. L.; Goodsell, R. M.; Iwaszkiewicz-Eggebrecht, E.; Ahlen, D.; Högvall, J.; Lundberg, E.; Rova, E.; Łukasik, P.; Ronquist, F.; Roslin, T.; Tack, A. J. M.
10.1101/2024.02.28.582312 — ecology — Posted on 2024-03-03
4851 Protein supersaturation powers innate immune signaling
Rodriguez Gama, A.; Miller, T.; Lange, J. J.; Wu, J.; Song, X.; Venkatesan, S.; Unruh, J.; Bradford, W.; Halfmann, R.
10.1101/2023.03.20.533581 — immunology — Posted on 2024-03-03
4852 MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal cultures
Sit, T. P.; Feord, R. C.; Dunn, A. W.; Chabros, J.; Oluigbo, D.; Smith, H. H.; Burn, L.; Chang, E.; Boschi, A.; Yuan, Y.; Gibbons, G. M.; Khayat-Khoei, M.; De Angelis, F.; Hemberg, E.; Hemberg, M.; Lancaster, M. A.; Lakatos, A.; Eglen, S. J.; Paulsen, O.; Mierau, S. B.
10.1101/2024.02.05.578738 — neuroscience — Posted on 2024-03-03
4853 Network States in the Basolateral Amygdala Predicts Voluntary Alcohol Consumption
DiLeo, A.; Antonoudiou, P.; Blandino, K.; Conlin, E.; Melon, L.; Maguire, J.
10.1101/2023.06.21.545962 — neuroscience — Posted on 2024-03-03
4854 Stand age diversity and climate change affect forests' resilience and stability, although unevenly
Vangi, E.; Dalmonech, D.; Cioccolo, E.; Marano, G.; Bianchini, L.; Puchi, P.; Grieco, E.; Cescatti, A.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2024-03-03
4855 Structural architecture of amyloid-β oligomers, curvilinear protofibrils and annular assemblies, imaged by cryo-EM and cryo-ET
Liang, R.; Torres-Flores, A. P.; Qi, S.; Khursheed, A.; Tian, Y.; Szwedziak, P.; Baker, M. D.; Volkov, V. A.; Darbari, V. C.; Viles, J. H.
10.1101/2024.03.01.582902 — biophysics — Posted on 2024-03-03
4857 Phase Separation and Aggregation of α-Synuclein Diverge at Different Salt Conditions
Sternke-Hoffmann, R.; Sun, X.; Menzel, A.; Pinto, M. d. S.; Venclovaite, U.; Woerdehoff, M. M.; Hoyer, W.; Zheng, W.; Luo, J.
10.1101/2024.03.01.582895 — biophysics — Posted on 2024-03-03
4858 LogoMotif: a comprehensive database of transcription factor binding site profiles in Actinobacteria
Augustijn, H. E.; Karapliafis, D.; Joosten, K.; Rigali, S.; van Wezel, G. P.; Medema, M. H.
10.1101/2024.02.28.582527 — bioinformatics — Posted on 2024-03-03
4859 Structural Requirements for Activity of Mind bomb1 in Notch Signaling
Cao, R.; Gozlan, O.; Tveriakhina, L.; Zhou, H.; Jiang, H.; Cole, P. A.; Aster, J. C.; Sprinzak, D.; Blacklow, S. C.
10.1101/2024.03.01.582834 — biochemistry — Posted on 2024-03-03
4860 Structure-guided aminoacylation and assembly of chimeric RNAs
Radakovic, A.; Lewicka, A.; Todisco, M.; Aitken, H. R. M.; Weiss, Z.; Kim, S.; Bannan, A.; Piccirilli, J. A.; Szostak, J. W.
10.1101/2024.03.02.583109 — biochemistry — Posted on 2024-03-03
4861 Natural Induction: Spontaneous adaptive organisation without natural selection
Buckley, C. L.; Lewens, T.; Levin, M.; Millidge, B.; Tschantz, A.; Watson, R. A.
10.1101/2024.02.28.582499 — evolutionary biology — Posted on 2024-03-03
4862 Cellular mechanotransduction of human osteoblasts in microgravity
Wubshet, N. H.; Cai, G.; Chen, S. J.; Sullivan, M.; Reeves, M.; Mays, D.; Harrison, M.; Varnado, P.; Yang, B. A.; Arreguin-Martinez, E.; Qu, Y.; Lin, S.-S.; Duran, P.; Aguilar, C. A.; Giza, S.; Clements, T.; Liu, A. P.
10.1101/2024.03.03.583164 — cell biology — Posted on 2024-03-03
4864 Quantitative profiling of human translation initiation reveals regulatory elements that potently affect endogenous and therapeutically modified mRNAs
Lewis, C. J. T.; Xie, L.; Bhandarkar, S.; Jin, D.; Abdallah, K. S.; Draycott, A. S.; Chen, Y.; Thoreen, C. C.; Gilbert, W. V.
10.1101/2024.02.28.582532 — systems biology — Posted on 2024-03-03
4868 Molecular mechanism of Mad2 conformational conversion promoted by the Mad2-interaction motif of Cdc20
Yu, C. W. H.; Fischer, E. S.; Greener, J. G.; Yang, J.; Zhang, Z.; Freund, S. M. V.; Barford, D.
10.1101/2024.03.03.583158 — biochemistry — Posted on 2024-03-03
4871 Metastable condensates suppress conversion to amyloid fibrils
Das, T.; Zaidi, F.; Farag, M.; Ruff, K. M.; Messing, J.; Taylor, J. P.; Pappu, R. V.; Mittag, T.
10.1101/2024.02.28.582569 — biophysics — Posted on 2024-03-03
4873 Geny: A Genotyping Tool for Allelic Decomposition of Killer Cell Immunoglobulin-Like Receptor Genes
Zhou, Q.; Ghezelji, M.; Hari, A.; Ford, M. K. B.; Holley, C.; COVNET Consortium, ; Mirabello, L.; Chanock, S.; Sahinalp, C.; Numanagic, I.
10.1101/2024.02.27.582413 — bioinformatics — Posted on 2024-03-03
4878 Changes in Walking Function and Neural Control following Pelvic Cancer Surgery with Reconstruction
Li, G.; Ao, D.; Vega, M. M.; Zandiyeh, P.; Chang, S.-H.; Penny, A. N.; Lewis, V. O.; Fregly, B. J.
10.1101/2024.02.27.582423 — bioengineering — Posted on 2024-03-03
4879 The Spx stress regulator confers high-level β-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin resistant Staphylococcus aureus
Nielsen, T. K.; Petersen, I. B.; Xu, L.; Barbuti, M. D.; Mebus, V. H.; Justh, A.; Alqarzaee, A. A.; Jacques, N.; Oury, C.; Thomas, V. C.; Kjos, M.; Henriksen, C.; Frees, D.
10.1101/2024.03.01.582999 — microbiology — Posted on 2024-03-03
4880 The aging-induced long non-coding RNA MIRIAL controls endothelial cell and mitochondrial function
Kohnle, C.; Koziarek, S.; Warwick, T.; Theodorou, K.; Fischer, A.; Juni, R. P.; Muhly Reinholz, M.; Busscher, D.; Lam, F.; Vetter, F.; Wagner, J. U. G.; Sommer, J.; Gimbel, A. T.; Stanicek, L.; Guenther, S.; Wittig, I.; Maegdefessel, L.; Leisegang, M. S.; Brandes, R. P.; Dimmeler, S.; Boon, R. A.
10.1101/2024.02.28.582649 — cell biology — Posted on 2024-03-03
4881 Early-stage lung adenocarcinoma is driven by an injury-associated, plastic cell state dependent on a KRAS-ITGA3-SRC axis
Moye, A. L.; Dost, A. F. M.; Ietswaart, R.; Sengupta, S.; Ya, V.; Aluya, C.; Fahey, C. G.; Louie, S. M.; Paschini, M.; Kim, C. F.
10.1101/2024.02.27.582165 — cancer biology — Posted on 2024-03-03
4882 Dark-based Optical Sectioning assists Background Removal in Fluorescence Microscopy
Cao, R.; Li, Y.; Wang, W.; Zhang, G.; Wang, G.; Sun, Y.; Renc, W.; Sun, J.; Hou, Y.; Xu, X.; Hu, J.; Lu, Y.; Li, C.; Wu, J.; Li, M.; Qu, J.; Xi, P.
10.1101/2024.03.02.578598 — bioinformatics — Posted on 2024-03-03
4884 Identification of an evolutionary conserved binding motif responsible for the recruitment of NMD factors to the UPF1 helicase
Barbarin-Bocahu, I.; Ulryck, N.; Rigobert, A.; Ruiz Gutierrez, N.; Decourty, L.; Raji, M.; Garkhal, B.; Le Hir, H.; Saveanu, C.; Graille, M.
10.1101/2024.02.27.582253 — biochemistry — Posted on 2024-03-03
4886 Evolution Under Thermal Stress Affects Escherichia colis Resistance to Antibiotics
Bullivant, A.; Lozano-Huntelman, N.; Tabibian, K.; Leung, V.; Armstrong, D.; Dudley, H.; Savage, V. M.; Rodriguez-Verdugo, A.; Yeh, P.
10.1101/2024.02.27.582334 — evolutionary biology — Posted on 2024-03-03
4887 The transcriptional regulator Lrp activates the expression of genes involved in tilivalline enterotoxin biosynthesis in Klebsiella oxytoca
De la Cruz, M. A.; Valdez-Salazar, H. A.; Robles-Leyva, N.; Siqueiros-Cendon, T.; Rascon-Cruz, Q.; Rodriguez-Valverde, D.; Leon-Montes, N.; Soria-Bustos, J.; Rosales-Reyes, R.; Cedillo, M. L.; Yanez-Santos, J. A.; Ibarra, J. A.; Torres, J.; Giron, J. A.; Fox, J. G.; Ares, M. A.
10.1101/2024.02.29.582825 — molecular biology — Posted on 2024-03-03
4888 The need for high-resolution gut microbiome characterization to design efficient strategies for sustainable aquaculture production
Gupta, S.; de Leon, A. V.-P.; Kodama, M.; Hötzinger, M.; Clausen, C. G.; Pless, L.; Verissimo, A.; Stengel, B.; Calabuig, V.; Kvingedal, R.; Skugor, S.; Westereng, B.; Harvey, T. N.; Nordborg, A.; Bertilsson, S.; Limborg, M. T.; Morkore, T.; Sandve, S. R.; Pope, P. B.; Hvidsten, T. R.; La Rosa, S. L.
10.1101/2024.02.29.582783 — microbiology — Posted on 2024-03-03
4889 Stand age diversity and climate change affects forests' resilience and stability, although unevenly
Vangi, E.; Dalmonech, D.; Cioccolo, E.; Marano, G.; Bianchini, L.; Puchi, P.; Grieco, E.; Cescatti, A.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2024-03-03
4893 Population estimates of shorebirds on the Atlantic Coast of southern South America generated from large-scale, simultaneous, volunteer-led surveys
Faria, F.; Aldabe, J.; Almeida, J.; Bonanno, J.; Bugoni, L.; Clay, R.; Garcia-Walther, J.; Gonzalez, A.; Lesterhuis, A.; Nunes, G.; Senner, N.
10.1101/2024.02.26.582090 — ecology — Posted on 2024-03-03
4894 Mycobacterium tuberculosis infection associated immune perturbations correlate with antiretroviral immunity
Tepekule Mueller, B.; Joerimann, L.; Schenkel, C. D.; Opitz, L.; Tschumi, J.; Wolfensberger, R.; Neumann, K.; Kusejko, K.; Zeeb, M.; Boeck, L.; Kaelin, M.; Notter, J.; Furrer, H.; Hoffmann, M.; Hirsch, H. H.; Calmy, A.; Cavassini, M.; Labhardt, N. D.; Bernasconi, E.; Metzner, K. J.; Braun, D. L.; Guenthard, H. F.; Kouyos, R. D.; Duffy, F.; Nemeth, J.; the Swiss HIV Cohort Study,
10.1101/2023.07.14.548872 — immunology — Posted on 2024-03-03
4895 Neurons in the ventral striatopallidal complex modulate lateral hypothalamic orexin/hypocretin neuron activity: Implications for reward-seeking
Mitchell, C. S.; Mohammadkhani, A.; Manning, E. E.; Campbell, E. J.; Fisher, S. D.; Yeoh, J. W.; Pearl, A. J.; Iredale, J. A.; Burton, N. J.; Qiao, M.; Bains, J. S.; McNally, G. P.; Andrews, Z. A.; Graham, B. A.; Scammel, T. E.; Lowell, B. B.; Kong, D.; Borgland, S. L.; Dayas, C. V.
10.1101/2020.03.05.979468 — neuroscience — Posted on 2024-03-03
4898 Structural insights into sphingosine 1-phosphate receptor 4 activation
Gao, W.; Gan, S.; Zhang, M.; Inoue, A.; Xie, M.; He, H.; Zhu, H.; Guo, S.; Qiu, C.; Chang, D.; Yu, J.; Deng, Z.; Ye, F.; Li, S.; Zhang, J.; Zhao, Z.; Xue, M.; Ofosuhene, B.; Xu, Y.; Lin, H.; Qian, X.; Zhu, L.; Du, Y.; Li, H.
10.1101/2024.03.02.583092 — biochemistry — Posted on 2024-03-03
4899 Arid5a uses disordered extensions of its core ARID domain for distinct DNA- and RNA-recognition and gene regulation
von Ehr, J.; Oberstrass, L.; Yazgan, E.; Schnaubelt, L. I.; Bluemel, N.; McNicoll, F.; Weigand, J. E.; Zarnack, K.; Mueller-McNicoll, M.; Korn, S. M.; Schlundt, A.
10.1101/2024.02.29.582703 — biochemistry — Posted on 2024-03-03
4900 Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allosterically
Nandwani, N.; Bhowmik, D.; Childers, M. C.; Goluguri, R. R.; Dawood, A.; Regnier, M.; Spudich, J. A.; Ruppel, K. M.
10.1101/2024.02.29.582851 — biochemistry — Posted on 2024-03-03
4904 A novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
Massoni, S. C.; Evans, N.; Hantke, I.; Fenton, C.; Torpey, J. H.; Collins, K. M.; Krysztofinska, E. M.; Muench, J. H.; Thapaliya, A.; Martinez-Lumbreras, S.; Martin, S. H.; Prior, C. B.; Turgay, K.; Isaacson, R. L.; Camp, A. H.
10.1101/2024.03.02.583065 — microbiology — Posted on 2024-03-03
4908 Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer
He, T.; Cheng, C.; Qiao, Y.; Cho, H.; Young, E.; Mannan, R.; Mahapatra, S.; Miner, S. J.; Zheng, Y.; Kim, N.; Zeng, V. Z.; Wisniewski, J. P.; Hou, S.; Jackson, B.; Cao, X.; Su, F.; Wang, R.; Chang, Y.; Kuila, B.; Mukherjee, S.; Dukare, S.; Aithal, K. B.; D.S., S.; Abbineni, C.; Lyssiotis, C. A.; Parolia, A.; Xiao, L.; Chinnaiyan, A. M.
10.1101/2024.02.29.582768 — cancer biology — Posted on 2024-03-03
4911 RNA G-quadruplexes and calcium ions synergistically induce Tau phase transition in vitro
Yabuki, Y.; Matsuo, K.; Komiya, G.; Kudo, K.; Hori, K.; Ikenoshita, S.; Kawata, Y.; Mizobata, T.; Shioda, N.
10.1101/2024.03.01.582861 — biochemistry — Posted on 2024-03-03
4913 Aroma compounds profile is affected by the initial yeast ratio in wort co-fermentations
Aguiar-Cervera, J.; Visinoni, F.; Zhang, P.; Hollywood, K.; Vrhovsek, U.; Severn, O.; Delneri, D.
10.1101/2024.03.01.583027 — microbiology — Posted on 2024-03-02
4914 Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus
Elsaman, H.; Golubtsov, E.; Brazil, S.; Ng, N.; Klugherz, I.; Dichtl, K.; Mueller, C.; Wagener, J.
10.1101/2024.03.02.582832 — microbiology — Posted on 2024-03-02
4917 The fork restart factor PHF6 interacts with RRM2 and binds to H3K56ac marked nascent DNA
Depestel, L.; Bekaert, S.-L.; Sanders, E.; Van Damme, C.; Eggermont, A.; Loontiens, S.; Tilleman, L.; Van Nieuwerburgh, F.; Delhaye, L.; Van Vlierberghe, P.; Eyckerman, S.; Speleman, F.; Durinck, K.
10.1101/2023.03.08.531704 — cancer biology — Posted on 2024-03-02
4919 Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria
Sastre-Dominguez, J.; DelaFuente, J.; Toribio-Celestino, L.; Herencias, C.; Herrador-Gomez, P.; Costas, C.; Hernandez-Garcia, M.; Canton, R.; Rodriguez-Beltran, J.; Santos-Lopez, A.; San Millan, A.
10.1101/2024.03.01.582297 — microbiology — Posted on 2024-03-02
4920 Biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing with RISER
Sneddon, A.; Ravindran, A.; Shanmuganandam, S.; Kanchi, M.; Hein, N.; Jiang, S.; Shirokikh, N. E.; Eyras, E.
10.1101/2022.11.29.518281 — bioinformatics — Posted on 2024-03-02
4921 Prediction of m6A and m5C at single-molecule resolution reveals a cooccurrence of RNA modifications across the transcriptome
Acera Mateos, P.; Sethi, A. J.; Ravindran, A.; Srivastava, A.; Woodward, K.; Mahmud, S.; Kanchi, M.; Guarnacci, M.; Xu, J.; Yuen, Z. W.-S.; Zhou, Y.; Sneddon, A.; Hamilton, W.; Gao, J.; Starrs, L. M.; Hayashi, R.; Wickramasinghe, V. O.; Zarnack, K.; Preiss, T.; Burgio, G.; Dehorter, N.; Shirokikh, N. E.; Eyras, E.
10.1101/2022.03.14.484124 — bioinformatics — Posted on 2024-03-02
4922 O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis
Masclef, L.; Ahmed, O.; Iannantuono, N.; Gagnon, J.; Gushul-Leclaire, M.; Boulay, k.; Estavoyer, B.; Echbicheb, M.; Poy, M.; Ali Boubacar, K.; Boubekeur, A.; Menggad, S.; Schcolnik-Cabrera, A.; Aurelio, B.; Bonneil, E.; Thibault, P.; Hulea, L.; Tanaka, Y.; Mallette, F. A.; Drouin, J.; Affar, E. B.
10.1101/2024.03.01.582838 — molecular biology — Posted on 2024-03-02
4923 Ultrastructural analysis reveals mitochondrial placement independent of synapse placement in fine caliber C. elegans neurons
Riboul, D. V.; Crill, S.; Oliva, C. D.; Restifo, M. G.; Joseph, R.; Joseph, K.; Nguyen, K. C.; Hall, D. H.; Fily, Y.; Macleod, G. T.
10.1101/2023.05.30.542959 — neuroscience — Posted on 2024-03-02
4929 Protein Kinase A is Functional Component of Focal Adhesions
Kang, M.; Senatore, A. J.; Naughton, H.; McTigue, M.; Beltman, R. J.; Herppich, A. A.; Pflum, M. K. H.; Howe, A. K.
10.1101/2023.08.18.553932 — cell biology — Posted on 2024-03-02
4930 Skeletal muscle effects of antisense oligonucleotides targeting glycogen synthase 1 in a mouse model of Pompe disease
Weiss, L.; Carrer, M.; Shmara, A.; Cheng, C.; Yin, H.; Ta, L.; Boock, V.; Fazeli, Y.; Chang, M.; Paguio, M.; Lee, J.; Yu, H.; Martin, A.; Raben, N.; Weiss, J.; Grossman, T.; Jafar-nejad, P.; Kimonis, V.
10.1101/2024.02.22.580414 — molecular biology — Posted on 2024-03-02
4931 Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses
Xiao, H.; Ulmert, I.; Bach, L.; Huber, J.; Narasimhan, H.; Kurochkin, I.; Chang, Y.; Holst, S.; Moerbe, U.; Zhang, L.; Schlitzer, A.; Pereira, F.; Schraml, B.; Baumjohann, D.; Lahl, K.
10.1101/2022.08.10.503322 — immunology — Posted on 2024-03-02
4932 Asparagine availability controls B cell homeostasis
Yazicioglu, Y. F.; Marin, E.; Bentkowska, K.; Andrew, H.; Mitchell, R.; Wong, Z. Y.; Fergusson, J.; Johnstone, J. C.; Ali, M.; Kronsteiner, B.; Coles, M.; Buckley, C.; Dunachie, S.; Clarke, A.
10.1101/2023.04.03.535433 — immunology — Posted on 2024-03-02
4933 Where top-down meets bottom-up: Cell-type specific connectivity map of the whisker system
Rault, N.; Bergmans, T.; Delfstra, N.; Kleijnen, B. J.; Zeldenrust, F.; Celikel, T.
10.1101/2023.07.31.551377 — neuroscience — Posted on 2024-03-02
4934 Skin keratinocyte-derived SIRT1 and BDNF modulate mechanical allodynia in mouse models of diabetic neuropathy
O'Brien, J.; Niehaus, P.; Chang, K.; Remark, J.; Barrett, J.; Dasgupta, A.; Adenegan, M.; Salimian, M.; Kevas, Y.; Chandrasekeran, K.; Kristian, T.; Chellappan, R.; Rubin, S.; Kiemen, A.; Lu, C. P.-J.; Russell, J.; Ho, C.-Y.
10.1101/2023.01.24.523981 — neuroscience — Posted on 2024-03-02
4935 Automated model discovery for human cardiac tissue: Discovering the best model and parameters
Martonova, D.; Peirlinck, M.; Linka, K.; Holzapfel, G. A.; Leyendecker, S.; Kuhl, E.
10.1101/2024.02.27.582427 — bioengineering — Posted on 2024-03-02
4936 Optically active, paper-based scaffolds for 3D cardiac tissue engineering
Guo, F.; Jooken, S.; Ahmad, A.; Yu, W.; Deschaume, O.; Thielemans, W.; Bartic, C.
10.1101/2024.03.01.582954 — bioengineering — Posted on 2024-03-02
4937 Latest RNA and DNA nanopore sequencing allows for rapid avian influenza profiling
Perlas, A.; Reska, T.; CROVILLE, G.; Tarres-Freixas, F.; Guerin, J.-L.; Majo, N.; Urban, L.
10.1101/2024.02.28.582540 — genomics — Posted on 2024-03-02
4938 Light-microscopy based dense connectomic reconstruction of mammalian brain tissue
Tavakoli, M. R.; Lyudchik, J.; Januszewski, M.; Vistunou, V.; Agudelo, N.; Vorlaufer, J.; Sommer, C.; Kreuzinger, C.; Oliveira, B.; Cenameri, A.; Novarino, G.; Jain, V.; Danzl, J. G.
10.1101/2024.03.01.582884 — neuroscience — Posted on 2024-03-02
4940 A novel tomato inter-specific (Solanum lycopersicum var. cerasiforme and S. pimpinellifolium) MAGIC population facilitates trait association and candidate gene discovery in untapped exotic germplasm
Arrones, A.; Antar, O.; Pereira-Dias, L.; Solana, A.; Ferrante, P.; Aprea, G.; Plazas, M.; Prohens, J.; Diez, M. J.; Giuliano, G.; Gramazio, P.; Vilanova, S.
10.1101/2024.02.28.582481 — plant biology — Posted on 2024-03-02
4941 Super Pangenome of Grapevines Empowers Improvement of the Oldest Domesticated Fruit
Guo, L.; Wang, X.; Ayhan, D. H.; Rhaman, M. S.; Yan, M.; Jiang, J.; Wang, D.; Zheng, W.; Mei, J.; Ji, W.; Jiao, J.; Chen, S.; Sun, J.; Yi, S.; Meng, D.; Wang, J.; Bhuiyan, M. N.; Qin, G.; Guo, L.; Yang, Q.; Zhang, X.; Sun, H.; Liu, C.; Ye, W.
10.1101/2024.02.28.582440 — plant biology — Posted on 2024-03-02
4943 Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior
Zeledon, E. V.; Baxt, L. A.; Khan, T. A.; Michino, M.; Miller, M.; Huggins, D. J.; Jiang, C. S.; Vosshall, L. B.; Duvall, L. B.
10.1101/2024.02.28.582529 — pharmacology and toxicology — Posted on 2024-03-02
4944 Identification of microRNAs regulated by E2F transcription factors in human pluripotent stem cells
Varela, M. S. R.; Vautier, M. F.; Mucci, S.; Isaja, L.; Fernandez, E. A.; Sevlever, G. E.; Scassa, M. E.; Romorini, L.
10.1101/2024.02.28.582539 — developmental biology — Posted on 2024-03-02
4946 Expression of fibroblast activation protein-α in human deep venous thrombus
Oguri, N.; Gi, T.; Nakamura, E.; Furukoji, E.; Goto, H.; Maekawa, K.; Tsuji, A. B.; Nishii, R.; Aman, M.; Moriguchi-Goto, S.; Sakae, T.; Azuma, M.; Yamashita, A.
10.1101/2024.02.27.582425 — pathology — Posted on 2024-03-02
4947 Nanogap Solid-State Single-Molecule Detection at Mars, Europa, and Microgravity Conditions
Ramirez-Colon, J. L.; Johnson, E.; Duzdevich, D.; Lee, S.; Soderblom, J.; Zuber, M. T.; Taniguchi, M.; Ohshiro, T.; Komoto, Y.; Carr, C. E.
10.1101/2024.02.29.582359 — biophysics — Posted on 2024-03-02
4949 CZ ID: a cloud-based, no-code platform enabling advanced long read metagenomic analysis
Simmonds, S. E.; Ly, L.; Lim, R.; Morse, T.; Thakku, S. G.; Rosario Cora, K.; Caballero Perez, J.; Puschnik, A. S.; Mwakibete, L.; Hickey, S.; Beaulaurier, J.; Tato, C.; CZ ID Team, ; Kalantar, K.
10.1101/2024.02.29.579666 — bioinformatics — Posted on 2024-03-02
4950 Phospho-Tune: Enhanced Structural Modeling of Phosphorylated Protein Interactions
Glukhov, E.; Averkava, V.; Kotelnikov, S.; Stepanenko, D.; Nguyen, T.; Mitchell, J. C.; Simmerling, C.; Vajda, S.; Emili, A.; Padhorny, D.; Kozakov, D.
10.1101/2024.02.29.582580 — bioinformatics — Posted on 2024-03-02
4951 PopGenPlayground: a population genomics analysis pipeline
Wolfsberger, W. W.; Shchubelka, K.; Oleksyk, O. T.; Hasynets, Y.; Patskun, S.; Vakerych, M.; Kish, R.; Mirutenko, V.; Mirutenko, V.; Cotoraci, C. A.; Pop, C.; Neagu, O.; Balta, C.; Herman, H.; Mare, P.; Dumitra, S.; Papiu, H.; Hermenean, A.; Oleksyk, T. K.
10.1101/2024.02.27.582400 — bioinformatics — Posted on 2024-03-02
4952 Expansion microscopy for super-resolution imaging of collagen-abundant tissues
Chuang, Y.-H.; Wu, Y.-F.; Lin, Y.-H.; Zhou, Y.-X.; Hsu, S.-C.; Lin, S.-J.; Chu, L.-A.
10.1101/2024.02.28.582497 — bioengineering — Posted on 2024-03-02
4953 Imaging of cellular dynamics in vitro and in situ: from a whole organism to sub-cellular imaging with self-driving, multi-scale microscopy
Daetwyler, S.; Mazloom-Farsibaf, H.; Zhou, F. Y.; Segal, D.; Sapoznik, E.; Westcott, J. M.; Brekken, R. A.; Danuser, G.; Fiolka, R. P.
10.1101/2024.02.28.582579 — bioengineering — Posted on 2024-03-02
4954 The fungal protein Jps1 facilitates unconventional protein secretion through a direct phosphoinositide interaction
Dali, S.; Schultz, M.; Koester, M.; Kamel, M.; Busch, M.; Steinchen, W.; Haensch, S.; Reiners, J.; Smits, S.; Kedrov, A.; Altegoer, F.; Schipper, K.
10.1101/2024.02.29.582524 — biochemistry — Posted on 2024-03-02
4957 3D Transcranial ultrasound localization microscopy reveals major arteries in the sheep brain
Coudert, A.; Denis, L.; Chavignon, A.; Bodard, S.; Naveau, M.; Pro Sistiaga, P.; Saulnier, R.; Orset, C.; Vivien, D.; Chappard, C.; Couture, O.
10.1101/2024.02.28.582489 — physiology — Posted on 2024-03-02
4959 Platinum drug reprogramming of protein phosphorylation
Qi, L.; Hou, Y.; Luo, Q.; Liu, X.; Zhang, Y.; Jia, F.; Fang, T.; Zhao, Y.; Wang, F.; Xu, Y.; Li, X.; Yu, W.; Wang, S.; Xin, B.; Sadler, P.
10.1101/2024.02.28.582513 — cancer biology — Posted on 2024-03-02
4960 PRMT5 inhibition preferentially targets MYCN-amplified neuroblastoma via altered transcriptional and splicing programmes regulating key cancer cell fitness pathways.
Bojko, J.; Kollareddy, M.; Szemes, M.; Bellamy, J.; Poon, E.; Moukachar, A.; Legge, D.; Vincent, E. E.; Jones, N.; Malik, S.; Greenhough, A.; Paterson, A.; Park, J. H.; Gallacher, K.; Chesler, L.; Malik, K.
10.1101/2024.02.28.582087 — cancer biology — Posted on 2024-03-02
4961 Karyotype Evolution in Response to Chemoradiotherapy and Upon Recurrence of Esophageal Adenocarcinomas.
van der Sluis, K.; Sandick, J. W.; Koemans, W. J.; van den Bosch, T.; Broeks, A.; Peters, D.; Seignette, I. M.; Rausch, C. R.; van Dijk, E.; Snaebjornsson, P.; van den Berg, J. G.; van Grieken, N. C. T.; Ylstra, B.; Carvalho, B.; Miedema, D. M.; Kodach, L. L.
10.1101/2024.02.28.582275 — bioinformatics — Posted on 2024-03-02
4962 Machine Learning Classification of 53BP1 Foci
Benitez-Jones, M. X.; Keegan, S.; Jamshahi, S.; Fenyo, D.
10.1101/2024.02.28.582150 — bioinformatics — Posted on 2024-03-02
4966 ROUA Database: 300 Human Genomes from the border of Ukraine and Romania
Shchubelka, K. K.; Wolfsberger, W.; Oleksyk, O.; Hasynets, Y.; Patskun, S.; Vakerych, M.; Kish, R.; Mirutenko, V.; Mirutenko, V.; Cotoraci, C. A.; Pop, C.; Neagu, O.; Balta, C.; Herman, H.; Mare, P.; Dumitra, S.; Papiu, H.; Hermenean, A.; Oleksyk, T. K.
10.1101/2024.02.27.582437 — genomics — Posted on 2024-03-02
4967 Arctic greening drives changes in the diet and gut microbiome of a resident herbivore with consequences for fitness
Kamenova, S.; Albon, S.; Loe, L. E.; Irvine, J.; Langvatn, R.; Gusarova, G.; de Muinck, E.; Trosvik, P.
10.1101/2024.02.27.582426 — ecology — Posted on 2024-03-02
4968 Single nucleus transcriptomics supports a role for CCNA2-induced human adult cardiomyocyte cytokinesis
Bouhamida, E.; Vadakke-Madathil, S.; Mathiyalagan, P.; Ranjan, A.; Sherman, C.; Miller, P. E.; Ghetti, A.; Abi-Gerges, N.; Chaudhry, H. W.
10.1101/2024.03.01.583057 — cell biology — Posted on 2024-03-02
4969 RIPK3 coordinates RHIM domain-dependent inflammatory transcription in neurons
Kofman, S. B.; Chu, L. H.; Ames, J. M.; Chavarria, S. D.; Lichauco, K.; Daniels, B. P.; Oberst, A.
10.1101/2024.02.29.582857 — immunology — Posted on 2024-03-02
4970 Single-nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root
Liu, X.; Zeng, Q.; Yang, H.; Li, W.; Chen, Q.; Yin, K.; Pan, Z.; Wang, K.; Luo, M.; Shu, C.; Zhou, Z.
10.1101/2024.02.27.582442 — pathology — Posted on 2024-03-02
4971 Aberrant subcellular localization of mismatch repair protein MLH1 dysregulates the cell cycle to create new therapeutic opportunities
Haricharan, S.; Mazumder, A.; DeWitt, T.; Oropeza, E.; Punturi, N.; Lozano, D.; Sajjadi, E.; Guerini-Rocco, E.; Venetis, K.; Ivanova, M.; Mane, E.; Fusco, N.
10.1101/2024.02.27.582389 — cancer biology — Posted on 2024-03-02
4972 Easy, fast and reproducible Stochastic Cellular Automata with 'chouca'
Genin, A.; Dupont, G.; Valencia, D.; Zucconi, M.; Avila-Thieme, M. I.; Navarrete, S.; Wieters, E.
10.1101/2023.11.08.566206 — ecology — Posted on 2024-03-02
4973 Omega-3 polyunsaturated fatty acids modify glucose metabolism in THP-1 monocytes
Byun, M. J.; Armon, R.; Souza, T.; Anderson, H. D.; Saleem, A.; Pauls, S. D.
10.1101/2024.03.01.582966 — cell biology — Posted on 2024-03-02
4977 Cytochrome oxidase requirements in Bordetella reveal insights into evolution towards life in the mammalian respiratory tract
McKay, L. S.; Spandrio, A. R.; Johnson, R. M.; Sobran, M. A.; Marlatt, S.; Mote, K. B.; Dedloff, M. R.; Nash, Z. M.; Julio, S. M.; Cotter, P. A.
10.1101/2024.02.29.582880 — microbiology — Posted on 2024-03-02
4978 Evolution of pH-sensitive transcription termination during adaptation to repeated long-term starvation.
Worthan, S. B.; McCarthy, R. D. P.; Delaleau, M.; Stikeleather, R.; Bratton, B. P.; Boudvillain, M.; Behringer, M. G.
10.1101/2024.03.01.582989 — microbiology — Posted on 2024-03-02
4979 Fes-deficient macrophages enhance CD8+ T cell priming and tumour control through increased proinflammatory cytokine production and presentation
Laight, B. J.; Dmytryk, N.; Harper, D.; Zhang, C. S.; Garven, A.; Simpson, A. L.; Berman, D. M.; Kment, J.; Alotaibi, F.; Shi, C.; Gao, Y.; Vlasschaert, C.; LeBrun, D.; Tyryshkin, K.; Craig, A.; Basta, S.; Koti, M.; Greer, P. A.
10.1101/2024.02.27.581601 — immunology — Posted on 2024-03-02
4981 Seminal root angle is associated with root system architecture in durum wheat
Kang, Y.; Rambla, C.; Haeften, S.; Fu, B.; Akinlade, O.; Potgieter, A.; Borrell, A.; Mace, E.; Jordan, D.; Alahmad, S.; Hickey, L.
10.1101/2024.02.27.582216 — plant biology — Posted on 2024-03-02
4982 Sterile kidney tissue injury induces neutrophil swarming in lung alveolar capillaries
Komaru, Y.; Ning, L.; Lama, C.; Suresh, A.; Kefaloyianni, E.; Miller, M. J.; Herrlich, A.
10.1101/2024.02.27.582396 — physiology — Posted on 2024-03-02
4983 PIKfyve controls dendritic cell function and tumor immunity
Choi, J. E.; Qiao, Y.; Kryczek, I.; Yu, J.; Gurkan, J.; Bao, Y.; Gondal, M.; Tien, J. C.-Y.; Maj, T.; Yazdani, S.; Parolia, A.; Xia, H.; Zhou, J.; Wei, S.; Grove, S.; Vatan, L.; Lin, H.; Li, G.; Zheng, Y.; Zhang, Y.; Cao, X.; Su, F.; Wang, R.; He, T.; Cieslik, M.; Green, M. D.; Zou, W.; Chinnaiyan, A. M.
10.1101/2024.02.28.582543 — cancer biology — Posted on 2024-03-02
4984 Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB
Osei, B.; May, B. H.; Stiefel, C. M.; West, K. L.; Zafar, M. K.; Thomoson, M. D.; Bergstrom, E.; Leung, J. W.; Enemark, E. J.; Byrd, A. K.
10.1101/2024.02.27.582415 — biochemistry — Posted on 2024-03-02
4986 Label-free imaging of cellular organization in living mammalian cells via external apodization phase-contrast microscopy
Sari, L. N.; Miyamoto, T.; Nishimura, T.; Kainoh, K.; Onodera, N.; Kano, M.; Masuda, M.; Tamura, Y.; Hayashi, Y.; Yamamoto, Y.; Takahashi, S.-I.; Mishima, Y.; Yoneyama, Y.; Takeuchi, Y.; Ohno, H.; Ohashi, Y.; Sekiya, M.; Matsuzaka, T.; Shimano, H.
10.1101/2024.03.01.582671 — cell biology — Posted on 2024-03-02
4988 Deciphering mixed infections by plant RNA virus and reconstructing complete genomes simultaneously present within-host
BANGRATZ, M.; COMTE, A.; BILLARD, E.; GUIGMA, A. K.; GANDOLFI, G.; KASSANKOGNO, A. I.; SEREME, D.; POULICARD, N.; TOLLENAERE, C.
10.1101/2024.02.29.582683 — molecular biology — Posted on 2024-03-02
4989 PTCHD1 interacts with the SNARE-associated protein SNAPIN in vitro via its first exoplasmic loop
Pastore, S. F.; Xie, C. T. Y.; Muhammad, T.; El-masri, S.; Frankland, P.; Hamel, P. A.; Vincent, J. B.
10.1101/2024.02.29.582618 — molecular biology — Posted on 2024-03-02
4991 Targeting Iron - Respiratory Reciprocity Promotes Bacterial Death
Sharifian Gh., M.; Norouzi, F.; Sorci, M.; Zaid, T. S.; Pier, G. B.; Achimovich, A. M.; Ongwae, G. M.; Liang, B.; Ryan, M.; Lemke, M.; Belfort, G.; Gadjeva, M.; Gahlmann, A.; Pires, M. M.; Venter, H.; Harris, T. E.; Laurie, G. W.
10.1101/2024.03.01.582947 — microbiology — Posted on 2024-03-02
4994 Hominin brain size increase has emerged from within-species encephalization
Puschel, T. A.; Nicholson, S. L.; Baker, J.; Barton, R. A.; Venditti, C.
10.1101/2024.02.29.582715 — paleontology — Posted on 2024-03-02
4997 On the dynamic contact angle of capillary-driven microflows in open channels
Tokihiro, J. C.; McManamen, A. M.; Phan, D. N.; Thongpang, S.; Blake, T. D.; Theberge, A. B.; Berthier, J.
10.1101/2023.04.24.537941 — bioengineering — Posted on 2024-03-02
5000 Disordered proteins interact with the chemical environment to tune their protective function during drying
KC, S.; Nguyen, K. H.; Nicholson, V.; Walgren, A.; Trent, T.; Gollub, E.; Ramero, S.; Holehouse, A. S.; Sukenik, S.; Boothby, T. C.
10.1101/2024.02.28.582506 — biochemistry — Posted on 2024-03-02
5001 A DNA base-specific sequence interposed between CRX and NRL contributes to RHODOPSIN expression.
Maritato, R.; Medugno, A.; D'Andretta, E.; De Riso, G.; Lupo, M.; Botta, S.; Marrocco, E.; Renda, M.; Sofia, M.; Mussolino, C.; Bacci, M. L.; Surace, E. M.
10.1101/2023.12.22.573078 — genetics — Posted on 2024-03-02
5003 A DIFFERENTIAL REQUIREMENT FOR THE CILIOPATHY GENE RPGRIP1L IN HUMAN AND MOUSE SPINAL PROGENITOR FATE SPECIFICATION
Wiegering, A.; Anselme, I.; Brunetti, L.; Metayer-Derout, L.; Calderon, D.; Thomas, S.; Nedelec, S.; Eschstruth, A.; Schneider-Maunoury, S.; STEDMAN, A.
10.1101/2024.02.28.582477 — developmental biology — Posted on 2024-03-02
5007 A quantitative pipeline to assess secretion of human leptin coding variants reveals mechanisms underlying leptin deficiencies
Baird, H. J. M.; Shun-Shion, A. S.; Mendes De Oliveira, E.; Stalder, D.; Eden, J.; Chambers, J. E.; Farooqi, I. S.; Gershlick, D. C.; Fazakerley, D. J.
10.1101/2024.03.01.582913 — cell biology — Posted on 2024-03-02
5009 A proximity complementation assay to identify small molecules that enhance the traffic of ABCA4 misfolding variants.
Piccolo, D.; Zarouchlioti, C.; Bellingham, J.; Guarascio, R.; Ziaka, K.; Molday, R. S.; Cheetham, M. E.
10.1101/2024.03.01.582985 — molecular biology — Posted on 2024-03-02
5011 Under the radar: differential responses of bed bugs to an entomopathogen, environmental bacteria, and a human pathogen
Walt, H. K.; Bronzato-Badial, A.; Maedo, S. E.; Hinton, J. A.; King, J. G.; Pietri, J.; Hoffmann, F. G.
10.1101/2024.02.28.582586 — molecular biology — Posted on 2024-03-02
5012 Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria
Sastre-Dominguez, J.; DelaFuente, J.; Toribio-Celestino, L.; Herencias, C.; Herrador-Gomez, P.; Costas, C.; Hernandez-Garcia, M.; Canton, R.; Rodriguez-Beltran, J.; Santos-Lopez, A.; San Millan, A.
10.1101/2024.03.01.582297 — microbiology — Posted on 2024-03-02
5013 Sticking together: Independent evolution of biofilm formation in different species of staphylococci has occurred multiple times via different pathways
Crossman, L.; Sims, L. P.; Dean, R.; Felgate, H. M.; Diaz Calvo, T.; Hill, C. L.; McNamara, I.; Webber, M. A.; Wain, J. A.
10.1101/2024.03.01.582901 — microbiology — Posted on 2024-03-02
5014 Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal
Cisneros, W. J.; Walter, M.; Soliman, S. H. A.; Simons, L. M.; Cornish, D.; Halle, A. W.; Kim, E.-Y.; Wolinsky, S. M.; Shilatifard, A.; Hultquist, J. F.
10.1101/2024.03.01.582881 — microbiology — Posted on 2024-03-02
5015 Tick-borne pathogens identified in Hyalomma marginatum (Acari: Ixodidae) collected from various vertebrate hosts in the South of France
Bernard, C.; Pollet, T.; Galon, C.; Joly Kukla, C.; Cicculli, V.; Falchi, A.; Grech-Angelini, S.; Poli, P.-E.; Bastien, M.; Combes, B.; Moutailler, S.; Holzmuller, P.; Vial, L.
10.1101/2024.03.01.582933 — microbiology — Posted on 2024-03-02
5017 A platform for the recombinant production of Group A Streptococcus glycoconjugate vaccines
Ajay Castro, S.; Passmore, I. J.; Ndeh, D.; Shaw, H. A.; Ruda, A.; Burns, K.; Thomson, S.; Nagar, R.; Alagesan, K.; Lucas, K.; Abouelhadid, S.; Reglinski, M.; Schwarz- Linek, U.; Mawas, F.; Widmalm, G.; Wren, B. W.; Dorfmueller, H. C.
10.1101/2024.03.01.582896 — microbiology — Posted on 2024-03-02
5018 Differential gene expression and chromatin accessibility in the rat medial prefrontal cortex mediating individual variability in vulnerability to opioid use
Liu, S. X.; Muelken, P.; Maxim, Z. L.; Ramakrishnan, A.; Estill, M. S.; LeSage, M. G.; Smethells, J. R.; Shen, L.; Tran, P. V.; Harris, A. C.; Gewirtz, J. C.
10.1101/2024.02.29.582799 — neuroscience — Posted on 2024-03-02
5020 Gluk4-containing kainate receptors regulate synaptic communication in the motor cortex and reduce axon degeneration in adult mice
Ricci, R.; Fletcher, J. L.; Makowiecki, K.; Pepper, R.; Fortune, A.; Cullen, C. L.; Connelly, W. M.; Charlesworth, J.; Blackburn, N. B.; Pitman, K. A.; Young, K.
10.1101/2024.02.29.582867 — neuroscience — Posted on 2024-03-02
5021 NEK1 haploinsufficiency impairs ciliogenesis in human iPSC-derived motoneurons and brain organoids
Sorce, M. N.; Invernizzi, S.; Casiraghi, V.; Santangelo, S.; Lattuada, C.; Podini, P.; Brusati, A.; Silva, A.; Peverelli, S.; Quattrini, A.; Silani, V.; Bossolasco, P.; Ratti, A.
10.1101/2024.02.29.582696 — neuroscience — Posted on 2024-03-02
5022 Macroscale brain states support the control of semantic cognition
Wang, X.; Krieger-Redwood, K.; Cui, Y.; Smallwood, J.; Du, Y.; Jefferies, E.
10.1101/2024.02.29.582250 — neuroscience — Posted on 2024-03-02
5023 Prothrombin Knockdown Protects Podocytes and Reduces Proteinuria in Glomerular Disease
Waller, A. P.; Wolfgang, K. J.; Pruner, I.; Stevenson, Z. S.; Abdelghani, E.; Muralidharan, K.; Wilkie, T. K.; Blissett, A. R.; Calomeni, E. P.; Vetter, T. A.; Brodsky, S. V.; Smoyer, W. E.; Nieman, M. T.; Kerlin, B. A.
10.1101/2023.06.20.544360 — physiology — Posted on 2024-03-02
5025 A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation.
Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Thompson, C.; Kural, C.; Shepherd, D. P.; Presse, S. P.
10.1101/2023.12.07.570701 — biophysics — Posted on 2024-03-02
5026 Metabolic phenotyping of healthy and diseased human RPE cells
Rizwan, S.; Toothman, B.; Li, B.; Engel, A. J.; Lim, R. R.; Chao, J. R.; Du, J.
10.1101/2024.02.28.582405 — biochemistry — Posted on 2024-03-02
5028 Integrated single-nuclei and spatial transcriptomic analysis reveals propagation of early acute vein harvest and distension injury signaling pathways following arterial implantation
Michaud, M. E.; Mota, L.; Bakhtiari, M.; Thomas, B. E.; Tomeo, J.; Pilcher, W.; Contreras, M.; Ferran, C.; Bhasin, S.; Pradhan-Nabzdyk, L.; LoGerfo, F. W.; Liang, P.; Bhasin, M.
10.1101/2023.10.31.564995 — genomics — Posted on 2024-03-02
5029 Genomic fingerprints of the world's soil ecosystems
Graham, E. B.; Garayburu-Caruso, V. A.; Wu, R.; Zheng, J.; Jones, G.; McClure, R.
10.1101/2023.11.02.563126 — ecology — Posted on 2024-03-02
5030 Sputum production and salivary microbiome in COVID-19 patients reveals oral-lung axis
Lu, K. Y.-F.; Alqaderi, H.; Bin Hasan, S.; Alhazmi, H.; Alghounaim, M.; Devarajan, S.; Freire, M.; Altabtbaei, K.
10.1101/2024.02.29.582705 — microbiology — Posted on 2024-03-01
5032 High-dimensional mass cytometry reveals stemness state heterogeneity in pancreatic ductal adenocarcinoma
Ervin, E. H.; Ahern, D.; Liu, F.; Rendek, A.; Soonawalla, Z.; Oppermann, U.; Hulley, P.; Pauklin, S.
10.1101/2024.02.27.582358 — cancer biology — Posted on 2024-03-01
5033 The diversity of clinical Mycobacterium abscessus isolates in morphology, glycopeptidolipids and infection rates in a macrophage model
Pichler, V.; Dalkilic, L.; Shoaib, G.; Shapira, T.; Rankine-Wilson, L.; Boudehen, Y.-M.; Chao, J.; Sexton, D. L.; Prieto, M. D.; Quon, B.; Tocheva, E. I.; Kremer, L.; Hsiao, W.; Av-Gay, Y.
10.1101/2024.02.29.582856 — microbiology — Posted on 2024-03-01
5036 Dual agonism of sodium iodide symporter function in vivo
Brookes, K.; Thornton, C. M.; Zha, L.; Kim, J.; Small, B.; Manivannan, S.; Nieto, H. R.; Adcock, H.; Bottegoni, G.; Cox, L. R.; Kannappan, V.; Wang, W.; Gorvin, C. M.; Jhiang, S.; Ringel, M. D.; Campbell, M. J.; Sunassee, K.; Blower, P. J.; Boelaert, K.; Smith, V. E.; Read, M. L.; McCabe, C. J.
10.1101/2024.02.27.582332 — cancer biology — Posted on 2024-03-01
5037 Increased dosage of wild-type KRAS protein drives KRAS-mutant lung tumorigenesis and drug resistance
Ivanisevic, T.; Magits, W.; Ma, Y.; Zhao, P.; Van Boxel, E.; Lechat, B.; Stites, E.; Vande Velde, G.; Sewduth, R.; Sablina, A.
10.1101/2024.02.27.582346 — cancer biology — Posted on 2024-03-01
5039 Compartment-Specific Antibody Correlates of Protection to SARS-CoV-2 Omicron in Macaques
Tong, X.; Wang, Q.; Jung, W.; Chicz, T. M.; Blanc, R.; Parker, L. J.; Barouch, D. H.; McNamara, R. P.
10.1101/2024.03.01.582951 — immunology — Posted on 2024-03-01
5041 High-throughput algorithm predicts F-Type ATP synthase rotor ring stoichiometries of 8 to 27 protomers
Osipov, S.; Zinoviev, E.; Anuchina, A.; Kuzmin, A.; Minaeva, A.; Ryzhykau, Y.; Vlasov, A.; Gushchin, I.
10.1101/2024.02.27.582367 — bioinformatics — Posted on 2024-03-01
5042 Using machine learning to count Antarctic shag (Leucocarbo bransfieldensis) nests on images captured by Remotely Piloted Aircraft Systems
Cusick, A.; Fudala, K.; Storozenko, P. P.; Swiezewski, J.; Kaleta, J.; Oosthuizen, W. C.; Pfeifer, C.; Bialik, R. J.
10.1101/2024.02.27.582379 — ecology — Posted on 2024-03-01
5045 Staphylococcus aureus lipid factors modulate melanoma clustering and invasion in zebrafish
Giese, M.; Ramakrishnan, G.; Steenberge, L.; Dovan, J.; Sauer, J.; Huttenlocher, A.
10.1101/2024.02.27.582365 — cancer biology — Posted on 2024-03-01
5046 HKDC1 Promotes Liver Cancer Stemness Under Hypoxia via Stabilizing β-Catenin
Fan, L.; Tian, C.; Yang, W.; Liu, X.; Dhungana, Y.; Tan, H.; Glazer, E. S.; Yu, J.; Peng, J.; Ma, L.; Ni, M.; Zhu, L.
10.1101/2024.02.27.581958 — cancer biology — Posted on 2024-03-01
5047 Circulating (poly)phenol metabolites in the brain: unveiling in vitro and in vivo blood-brain barrier transport
Carecho, R.; Marques, D.; Carregosa, D.; Masuero, D.; Garcia-Aloy, M.; Tramer, F.; Passamonti, S.; Vrhovsek, U.; Ventura, R.; Brito, M. A.; Nunes dos Santos, C.; Figueira, I.
10.1101/2024.02.27.582339 — biochemistry — Posted on 2024-03-01
5049 Cognate Antigen Engagement Induces HIV-1 Expression In CD4+ T Cells From People On Long-Term ART
Moskovjlevic, M.; Dragoni, F.; Board, N. L.; Wu, F.; Lai, J.; Zhang, H.; White, J. R.; Ho, R.; Lynn, K.; Tebas, P.; Mounzer, K.; Deeks, S. G.; Montaner, L. J.; Siliciano, J. D.; Simonetti, F. R.; Siliciano, R. F.
10.1101/2024.02.27.582096 — immunology — Posted on 2024-03-01
5050 Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5
Harrison, T.; Alam, N.; Farrell, B.; Quinkert, D.; Lias, A.; King, L.; Draper, S. J.; Higgins, M. K.; Campeotto, I.
10.1101/2024.02.29.582763 — immunology — Posted on 2024-03-01
5056 Arf family GTPases are present in Asgard archaea
Vargova, R.; Chevreau, R.; Alves, M.; Courbin, C.; Terry, K.; Legrand, P.; Elias, M.; Menetrey, J.; Dacks, J. B.; Jackson, C. L.
10.1101/2024.02.28.582541 — evolutionary biology — Posted on 2024-03-01
5057 High resolution live cell imaging to define ultrastructural and dynamic features of the halotolerant yeast Debaryomyces hansenii
Xelhuantzi, M. S. C.; Ghete, D.; Milburn, A.; Ioannou, S.; Mudd, P.; Calder, G.; Ramos, J.; O'Toole, P. J.; Genever, P. G.; MacDonald, C.
10.1101/2024.03.01.582977 — cell biology — Posted on 2024-03-01
5058 The USH3A causative gene clarin1 functions in Muller glia to maintain retinal photoreceptors
Nonarath, H. J. T.; Simpson, S. L.; Slobodianuk, T. L.; Collery, R. F.; Dinculescu, A.; Link, B. A.
10.1101/2024.02.29.582878 — cell biology — Posted on 2024-03-01
5059 Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis
Dill-McFarland, K. A.; Simmons, J. D.; Peterson, G. J.; Nguyen, F. K.; Campo, M.; Benchek, P.; Stein, C.; Vaisar, T.; Mayanja-Kizza, H.; Boom, W. H.; Hawn, T.
10.1101/2024.02.27.582348 — immunology — Posted on 2024-03-01
5063 Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived sSCF
Mao, C.; Chen, Y.; xing, d.; zhang, t.; Mei, D.; han, z.; xie, w.; Long, C.; Lin, Y.; yu, j.; Xiang, D.; Lu, M.; shen, x.; xue, x.
10.1101/2024.02.27.582307 — immunology — Posted on 2024-03-01
5065 Retrograde tracing of breast cancer-associated sensory neurons
Kallogjerovic, S.; Velazquez Quesada, I.; Hadap, R.; Gligorijevic, B.
10.1101/2024.02.26.582088 — cancer biology — Posted on 2024-03-01
5066 Macrophages foster adaptive anti-tumor immunity by ZEB1-dependent cytotoxic T cell chemoattraction
Fuchs, K.; Armstark, I.; van Roey, R.; Hajjaj, Y.; D`Avanzo, E.; Liguori, R.; Ferrazzi, F.; Ackermann, J.; Amon, L.; Alfredo, M.; Faas, M.; Huebner, J.; Hoffmann, M. H.; Kroenke, G.; Becker, C.; Dudziak, D.; Nimmerjahn, F.; Brabletz, S.; Stemmler, M. P.; Brabletz, T.; Schuhwerk, H.
10.1101/2024.02.26.582102 — cancer biology — Posted on 2024-03-01
5067 Armored Bicistronic CAR T Cells with Dominant-negative TGF-β Receptor II to Overcome Resistance in Glioblastoma.
Li, N.; Rodriguez, J. L.; Yin, Y.; Logun, M. T.; Yu, S.; Hicks, K. A.; Zhang, V.; Zhang, L.; Xie, C.; Wang, J.; Fraietta, J. A.; Binder, Z. A.; Lin, Z.; O'Rourke, D. M.
10.1101/2024.02.26.582107 — cancer biology — Posted on 2024-03-01
5068 DACIT: Device for Axon - Cancer cell Interaction Testing in 2D and 3D
Velazquez Quesada, I.; Allison, K.; Alizadeh, V.; Hesketh, N.; Thomas, G.; Tuzel, E.; Gligorijevic, B.
10.1101/2024.02.26.582218 — cancer biology — Posted on 2024-03-01
5069 Spatial transcriptomics profiling of gallbladder adenocarcinoma: a detailed two-case study of progression from precursor lesions to cancer
Pirenne, S.; Manzano-Nunez, F.; Loriot, A.; Cordi, S.; Desmet, L.; Aydin, S.; Hubert, C.; Toffoli, S.; Limaye, N.; Sempoux, C.; Komuta, M.; Gatto, L.; Lemaigre, F. P.
10.1101/2024.02.27.582232 — cancer biology — Posted on 2024-03-01
5071 Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk using QCM-D
Kerivan, E. M.; Amari, V. N.; Weeks, W. B.; Hardin, L. H.; Tobin, L.; Alazzam, O. Y.; Reinemann, D.
10.1101/2024.02.26.582155 — biophysics — Posted on 2024-03-01
5073 N-formylation modifies membrane damage associated to PSMα3 interfacial fibrillation
Bonnecaze, L.; Jumel, K.; Vial, A.; Khemtemourian, L.; Feuillie, C.; Molinari, M.; Lecomte, S.; Mathelie-Guinlet, M.
10.1101/2024.02.27.582255 — biophysics — Posted on 2024-03-01
5079 Exploring a large cancer cell line RNA-sequencing dataset with k-mers
Bessiere, C.; Xue, H.; Guibert, B.; Boureux, A.; Ruffle, F.; Viot, J.; Chikhi, R.; Salson, M.; Marchet, C.; Commes, T.; Gautheret, D.
10.1101/2024.02.27.581927 — bioinformatics — Posted on 2024-03-01
5080 mulea - an R package for enrichment analysis using multiple ontologies and empirical FDR correction
Turek, C.; Olbei, M.; Stirling, T.; Fekete, G.; Tasnadi, E.; Gul, L.; Bohar, B.; Papp, B.; Jurkowski, W.; Ari, E.
10.1101/2024.02.28.582444 — bioinformatics — Posted on 2024-03-01
5084 Device Design and Diagnostic Imaging of Radiopaque 3D Printed Tissue Engineering Scaffolds
Delemeester, M.; Pawelec, K.; Hix, J.; Siegenthaler, J.; Lissy, M.; Douek, P.; Hoummeau, A.; Si-Mohamed, S.; Shapiro, E.
10.1101/2024.02.26.582070 — bioengineering — Posted on 2024-03-01
5090 Deep learning modeling of ribosome profiling reveals regulatory underpinnings of translatome and interprets disease variants
He, J.; Xiong, L.; Shi, S.; Li, C.; Chen, K.; Fang, Q.; Nan, J.; Ding, K.; Li, J.; Mao, Y.; Boix, C. A.; Hu, X.; Kellis, M.; Xiong, X.
10.1101/2024.02.26.582217 — genomics — Posted on 2024-03-01
5091 Assessing methylation detection for primary human tissue using Nanopore sequencing
Genner, R.; Akeson, S.; Meredith, M.; Jerez, P. A.; Malik, L.; Baker, B.; Miano-Burkhardt, A.; Team, C.-l.-r.; Paten, B.; Billingsley, K. J.; Blauwendraat, C.; Jain, M.
10.1101/2024.02.29.581569 — genomics — Posted on 2024-03-01
5093 Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner
Senaldi, L.; Hassan, N.; Cullen, S.; Balaji, U.; Trigg, N.; Gu, J.; Finkelstein, H.; Phillips, K.; Conine, C.; Smith-Raska, M.
10.1101/2024.02.27.582278 — genetics — Posted on 2024-03-01
5096 Factors that influence the caste ratio in a bacterial division of labour
Avitia Dominguez, L.; Yu, Z.; Chopra, V.; Merks, R. M. H.; van Dijk, B.; Rozen, D.
10.1101/2024.02.28.582448 — evolutionary biology — Posted on 2024-03-01
5098 Phylogeny, morphology, virulence, ecology, and host range of Ordospora pajunii (Ordosporidae), a microsporidian symbiont of Daphnia spp.
Dziuba, M. K.; McIntire, K. M.; Seto, K.; Davenport, E. S.; Rogalski, M. A.; Gowler, C. D.; Baird, E.; Vaandrager, M.; Huerta, C.; Jaye, R.; Corcoran, F. E.; Withrow, A.; Ahrendt, S.; Salamov, A.; Nolan, M.; Tejomurthula, S.; Barry, K.; Grigoriev, I.; James, T.; Duffy, M. A.
10.1101/2023.04.21.537887 — ecology — Posted on 2024-03-01
5099 How to quantify developmental synchrony in malaria parasites
Greischar, M. A.; Savill, N. J.; Reece, S. E.; Mideo, N.
10.1101/2024.02.27.582296 — ecology — Posted on 2024-03-01
5100 Senescence of endplate osteoclasts induces sensory innervation and spinal pain
Pan, D.; Benkato, K. G.; Han, X.; Zheng, J.; Kumar, V.; Wan, M.; Zheng, J.; Cao, X.
10.1101/2023.10.26.564218 — cell biology — Posted on 2024-03-01
5101 FHOD-1/profilin-mediated actin assembly protect sarcomeres against contraction-induced deformation in C. elegans
Kimmich, M. J.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.
10.1101/2024.02.29.582848 — cell biology — Posted on 2024-03-01
5104 HDAC1 controls the generation and maintenance of effector-like CD8+ T cells during chronic viral infection
Rica, R.; Waldherr, M.; Schülein, M.; Miyakoda, E.; Sandner, L.; Stolz, V.; Waltenberger, D.; Krausgruber, T.; Bock, C.; Boucheron, N.; Ellmeier, W.; Sakaguchi, S.
10.1101/2024.02.28.580886 — immunology — Posted on 2024-03-01
5105 Dynamic role of monocytes and meningeal macrophages in bacterial meningoencephalitis
Gres, V.; Lohrmann, F.; Fuchs, V.; Pahutan Bosch, L. F.; Lösslein, A. K.; Neuber, J.; Mansoori Moghadam, Z.; Martins, T.; Baasch, S.; Henschel, J.; Freudenhammer, M.; Prinz, M.; Kierdorf, K.; Kolter, J.; Erny, D.; Henneke, P.
10.1101/2024.02.27.582183 — immunology — Posted on 2024-03-01
5107 A general strategy to engineer high-performance mammalian Whole-Cell Biosensors
Mallozzi, A.; Fusco, V.; Ragazzini, F.; Praznik, A.; Jerala, R.; di Bernardo, D.
10.1101/2024.02.28.582526 — synthetic biology — Posted on 2024-03-01
5108 Chitosan induces salicylic acid local and systemically in banana plants and reduces colonization by the pathogen Fusarium oxysporum f. sp. cubense TR4
Lopez-Moya, F.; Zorrilla-Fontanesi, J.; Lozano-Soria, A.; Fernandez-De Larrinoa Ganado, N.; Moreno-Gonzalez, C. M.; Hernandez, A.; Torres, A.; Gonzalez-Silvera, D.; Gunse, B.; Lopez-Jimenez, J. A.; Lopez-Llorca, L. V.
10.1101/2024.02.27.582266 — plant biology — Posted on 2024-03-01
5109 Chromosome-scale pearl millet genomes reveal a CARLACTONOIC ACID METHYL TRANSFERASE as key determinant of strigolactone pattern and Striga susceptibility
Kuijer, H. N.; Wang, J. Y.; Bougouffa, S.; Abrouk, M.; Jamil, M.; Incitti, R.; Alam, I.; Balakrishna, A.; Alvarez, D.; Votta, C.; Chen, G.-T.; Martinez, C.; Zuccolo, A.; Berqdar, L.; Sioud, S.; Fiorilli, V. N.; de Lera, A. R.; Lanfranco, L.; Gojobori, T.; Wing, R. A.; Krattinger, S.; Gao, X.; Al-Babili, S.
10.1101/2024.02.28.582441 — plant biology — Posted on 2024-03-01
5112 Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice
Mahmood, S.; Morrice, N. Z.; Thompson, D.; Milanizadeh, S.; Wilson, S.; Whitfield, P. D.; Mcilroy, G. D.; Rochford, J. J.; Mody, N.
10.1101/2024.02.27.582262 — physiology — Posted on 2024-03-01
5114 Bio-guided isolation of a new sesquiterpene from Artemisia cina with anthelmintic activity against Haemonchus contortus L3 infective larvae
Arango-De la Pava, L. D.; Gonzalez-Cortazar, M.; Zamilpa, A.; Cuellar-Ordaz, J. A.; de la Cruz-Cruz, H. A.; Higuera-Piedrahita, R. I.; Lopez-Arellano, R.
10.1101/2024.02.26.582230 — pharmacology and toxicology — Posted on 2024-03-01
5115 SIEGA the integrated genomic surveillance system of Andalusia, a One Health regional resource connected with the clinic
Casimiro-Soriguer, C. S.; Perez-Florido, J.; Robles, E. A.; Lara, M.; Aguado, A.; Iglesias, M. A. R.; Lepe, J. A.; Garcia, F.; Perez-Alegre, M.; Andujar, E.; Jimenez, V. E.; Camino, L. P.; Lorusso, N.; Ameyugo, U.; Vazquez, I. M.; Lozano, C. M.; Chaves, J. A.; Dopazo, J.
10.1101/2024.02.29.582716 — microbiology — Posted on 2024-03-01
5117 The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness
Zeng, H.; Zhu, X.; Wu, Y.; Li, Y.; Zhou, X.; Watzlawik, J.; Chen, Y. M.; Raybuck, A.; Billadeau, D.; Shapiro, V.; Springer, W.; Sun, J.; Boothby, M. R.
10.1101/2024.02.26.582122 — immunology — Posted on 2024-03-01
5119 HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in in vitro and in vivo models of amyotrophic lateral sclerosis
Silvestri, B.; Mochi, M.; Mawrie, D.; de Turris, V.; Colantoni, A.; Borhy, B.; Medici, M.; Anderson, E. N.; Garone, M. G.; Zammerilla, C. P.; Pandey, U. B.; Rosa, A.
10.1101/2023.08.22.554258 — neuroscience — Posted on 2024-03-01
5122 A Micro-scale Humanized Ventilator-on-a-Chip to Examine the Injurious Effects of Mechanical Ventilation
Gabela-Zuniga, B.; Shukla, V. C.; Bobba, C.; Higuita-Castro, N.; Powell, H. M.; Englert, J. A.; Ghadiali, S. N.
10.1101/2024.02.26.582200 — bioengineering — Posted on 2024-03-01
5123 Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells
Cloarec-Ung, F.-M.; Beaulieu, J.; Suthananthan, A.; Lehnertz, B.; Sauvageau, G.; Sheppard, H. M.; Knapp, D. J.
10.1101/2023.05.26.542436 — bioengineering — Posted on 2024-03-01
5126 CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit
Yi, F.; Cohen, T.; Zimmerman, N.; Dundar, F. A.; Zumbo, P.; Eltilib, R.; Brophy, E. J.; Arkin, H.; Feucht, J.; Gormally, M. V.; Hackett, C. S.; Kropp, K. N.; Etxeberria, I.; Chandran, S. S.; Park, J. H.; Hsu, K. C.; Sadelain, M.; Betel, D.; Klebanoff, C. A.
10.1101/2024.02.26.582108 — immunology — Posted on 2024-03-01
5127 Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension
Harvey, L. D.; Alotaibi, M.; Kim, H.-J. J.; Tai, Y.-Y.; Tang, Y.; Sun, W.; El Khoury, W.; Woodcock, C.-S. C.; Aaraj, Y. A.; St. Croix, C. M.; Stolz, D. B.; Lee, J.; Cheng, M. H.; Schwantes-An, T.-H.; Desai, A. A.; Pauciulo, M. W.; Nichols, W. C.; Webb, A.; Lafyatis, R.; Nouraie, M.; Wu, H.; McDonald, J. G.; Chauvet, C.; Cheng, S.; Bahar, I.; Bertero, T.; Benza, R. L.; Jain, M.; Chan, S. Y.
10.1101/2024.02.26.582142 — physiology — Posted on 2024-03-01
5130 Optimal inventorying and monitoring of taxonomic, phylogenetic and functional diversity
Cardoso, P.; Arnedo, M. A.; Macias-Hernandez, N.; Carvalho, W. D.; Carvalho, J. C.; Hilario, R.
10.1101/060400 — ecology — Posted on 2024-03-01
5133 Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination
Clark, J.; Hoxie, I.; Adelsberg, D.; Sapse, I.; Andreata-Santos, R.; Yong, J.; Amanat, F.; Tcheou, J.; Raskin, A.; Singh, G.; Gonzalez-Dominguez, I.; Edgar, J.; Bournazos, S.; Sun, W.; Carreno, J. M.; Simon, V.; Ellebedy, A.; Bajic, G.; Krammer, F.
10.1101/2024.02.28.582613 — immunology — Posted on 2024-03-01
5135 Advancing single cell technology: iSCseq drives living subcellular transcriptomic profiling in osteoimmune diversity
Okada, H.; Terui, Y.; Seki, M.; Terashima, A.; Tani, S.; Motooka, D.; Kanazawa, S.; Hosonuma, M.; Miyahara, J.; Makabe, K.; Omata, Y.; Onodera, S.; Yano, F.; Kajiya, H.; Gori, F.; Saito, T.; Okabe, K.; Suzuki, Y.; Baron, R.; Chung, U.-i.; Tanaka, S.; Hojo, H.
10.1101/2022.09.05.506360 — genomics — Posted on 2024-03-01
5136 Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
Aramburu, O.; Pardo, B. G.; Rodriguez-Villamayor, P.; Blanco Hortas, A.; Lamas, J.; Dewari, P. S.; Perojil, D.; Boudinot, P.; Macqueen, D. J.; Bouza, C.; Martinez, P.
10.1101/2024.02.15.580452 — genomics — Posted on 2024-03-01
5144 Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice
Fischer, A. A. M.; Robertson, H. B.; Kong, D.; Grimm, M. M.; Grether, J.; Groth, J.; Baltes, C.; Fliegauf, M.; Lautenschlaeger, F.; Grimbacher, B.; Ye, H.; Helms, V.; Weber, W.
10.1101/2023.10.16.562453 — synthetic biology — Posted on 2024-03-01
5145 The landscape of biomedical research
Gonzalez-Marquez, R.; Schmidt, L.; Schmidt, B. M.; Berens, P.; Kobak, D.
10.1101/2023.04.10.536208 — scientific communication and education — Posted on 2024-03-01
5148 Cancer immunotherapy responses persist after lymph node resection
Zhou, H.; Baish, J. W.; O'Melia, M. J.; Darragh, L. B.; Specht, E.; Czapla, J.; Lei, P.-j.; Menzel, L.; Rajotte, J. J.; Nikmaneshi, M. R.; Razavi, M. S.; Vander Heiden, M. G.; Ubellacker, J. M.; Munn, L. L.; Boland, G. M.; Cohen, S.; Karam, S. D.; Padera, T. P.
10.1101/2023.09.19.558262 — cancer biology — Posted on 2024-03-01
5149 NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis
Parolia, A.; Eyunni, S.; Verma, B. K.; Young, E.; Liu, L.; George, J.; Aras, S.; Das, C. K.; Mannan, R.; ur Rasool, R.; Luo, J.; Carson, S. E.; Mitchell-Velasquez, E.; Liu, Y.; Xiao, L.; Gajjala, P. R.; Jaber, M.; He, T.; Qiao, Y.; Pang, M.; Zhang, Y.; Alhusayan, M.; Cao, X.; Tavana, O.; Hou, C.; Wang, Z.; Ding, K.; Chinnaiyan, A. M.; Asangani, I. A.
10.1101/2024.02.22.581560 — cancer biology — Posted on 2024-03-01
5150 ConBoTNet: supervised contrastive learning enhances MHC-II peptide binding affinity prediction
Shen, L.-C.; Yan, L.; Liu, Z.; Zhang, Y.; Wang, Z.; Guo, Y.; Rossjohn, J.; Song, J.; Yu, D.-J.
10.1101/2023.12.21.572942 — bioinformatics — Posted on 2024-03-01
5151 FLOP: Tasks for Fitness Landscapes Of Protein wildtypes
Groth, P. M.; Michael, R.; Salomon, J.; Tian, P.; Boomsma, W.
10.1101/2023.06.21.545880 — bioinformatics — Posted on 2024-03-01
5152 Interactive visualisation of raw nanopore signal data with Squigualiser
Samarakoon, H.; Liyanage, K.; Ferguson, J.; Parameswaran, S.; Gamaarachchi, H.; Deveson, I.
10.1101/2024.02.19.581111 — bioinformatics — Posted on 2024-03-01
5154 Engineering an Escherichia coli strain for production of long single-stranded DNA
Shen, K.; Flood, J. J.; Zhang, Z.; Ha, A.; Shy, B. R.; Dueber, J. E.; Douglas, S. M.
10.1101/2024.02.27.582394 — bioengineering — Posted on 2024-03-01
5155 Microwave assisted acidification for green hydrogen and organic acids production
Barth, M.; Werner, M.; Otto, P.; Richwien, B.; Bahramsari, S.; Krause, M.; Schwan, B.; Abendroth, C.
10.1101/2023.11.18.567651 — bioengineering — Posted on 2024-03-01
5156 ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies
Bartolome, A.; Heiby, J. C.; Di Fraia, D.; Heinze, I.; Knaudt, H.; Spaeth, E.; Omrani, O.; Minetti, A.; Hofmann, M.; Kirkpatrick, J. M.; Dau, T.; Ori, A.
10.1101/2022.08.09.503299 — biochemistry — Posted on 2024-03-01
5157 Eco-evolutionary dynamics of partially migratory metapopulations in spatially and seasonally varying environments
Haaland, T. R.; Payo-Payo, A.; Acker, P.; Fortuna, R. R.; Burthe, S.; Ratikainen, I. I.; Daunt, F.; Reid, J. M.
10.1101/2023.11.28.568986 — evolutionary biology — Posted on 2024-03-01
5160 miR-203 controls developmental timing and early fate restriction during preimplantation embryogenesis
Gonzalez-Martinez, J.; Sanchez-Belmonte, A.; Ayala, E.; Garcia, A.; Nogueira, E.; Munoz, J.; Melati, A.; Gimenez, D.; Losada, A.; Ortega, S.; Malumbres, M.
10.1101/2024.02.06.579214 — developmental biology — Posted on 2024-03-01
5164 The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures
Antunes, B.; Zanchi, C.; Johnston, P. R.; Maron, B.; Witzany, C.; Regoes, R. R.; Hayouka, Z.; Rolff, J.
10.1101/2024.02.22.581582 — microbiology — Posted on 2024-03-01
5165 Human MX1 orchestrates the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs
McKellar, J.; Garcia de Gracia, F.; Aube, C.; Chaves Valadao, A. L.; Tauziet, M.; Arnaud-Arnould, M.; Rebendenne, A.; Neyret, A.; Labaronne, E.; Ricci, E. P.; Delaval, B.; Gaudin, R.; Naffakh, N.; Gallois-Montbrun, S.; Moncorge, O.; Goujon, C.
10.1101/2024.02.22.581565 — microbiology — Posted on 2024-03-01
5167 Natural variation of immune epitopes reveals intrabacterial antagonism
Stevens, D. M.; Moreno-Perez, A.; Weisberg, A. J.; Ramsing, C.; Fliegmann, J.; Zhang, N.; Madrigal, M.; Martin, G.; Steinbrenner, A.; Felix, G.; Coaker, G.
10.1101/2023.09.21.558511 — microbiology — Posted on 2024-03-01
5168 E. coli leverages growth arrest to remodel its proteome upon entry into starvation
Gervais, T.; Kscheschinski, B.; Mell, M.; Goepfert, N.; van Nimwegen, E.; Julou, T.
10.1101/2024.02.29.582700 — microbiology — Posted on 2024-03-01
5171 Speech prosody enhances the neural processing of syntax
Degano, G.; Donhauser, P.; Gwilliams, L.; Merlo, P.; Golestani, N.
10.1101/2023.07.03.547482 — neuroscience — Posted on 2024-03-01
5173 Minimum Effective Dose of Clemastine in a Mouse Model of Preterm White Matter Injury
Odell, E. P.; Jabassini, N.; Schniedewind, B.; Pease-Raissi, S. E.; Frymoyer, A.; Christians, U.; Green, A. J.; Chan, J. R.; Ostrem, B. E. L.
10.1101/2024.02.08.578953 — neuroscience — Posted on 2024-03-01
5175 Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1
Kupke, J.; Klimmt, J.; Mudlaff, F.; Schwab, M.; Lutsik, P.; Plass, C.; Sticht, C.; Oliveira, A. M. M.
10.1101/2023.05.22.541739 — neuroscience — Posted on 2024-03-01
5178 Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI
Zhu, A. H.; Nir, T. M.; Javid, S.; Villalon-Reina, J. E.; Rodrigue, A. L.; Strike, L. T.; de Zubicaray, G. I.; McMahon, K. L.; Wright, M. J.; Medland, S. E.; Blangero, J. E.; Glahn, D. C.; Kochunov, P.; Haberg, A. K.; Thompson, P. M.; Jahanshad, N.
10.1101/2024.02.22.581646 — neuroscience — Posted on 2024-03-01
5182 Medial accumbens shell spiny projection neurons encode relative reward preference
Pedersen, C. E.; Gowrishankar, R.; Piantadosi, S. C.; Castro, D. C.; Hjort, M. M.; Zhou, Z. C.; Kan, S. A.; Murphy, P. J.; O'Neill, P. R.; Bruchas, M.
10.1101/2022.09.18.508426 — neuroscience — Posted on 2024-03-01
5184 Architecture and flexibility of native kinetochores revealed by structural studies utilizing a thermophilic yeast
Barrero, D. J.; Wijeratne, S. S.; Zhao, X.; Cunningham, G. F.; Yan, R.; Nelson, C. R.; Arimura, Y.; Funabiki, H.; Asbury, C. L.; Yu, Z.; Subramanian, R.; Biggins, S.
10.1101/2024.02.28.582571 — biophysics — Posted on 2024-03-01
5185 Magnesium Transporter MgtA revealed as a Dimeric P-type ATPase
Zeinert, R.; Zhou, F.; Franco, P. H. C.; Zoeller, J.; Lessen, H.; Aravind, L.; Langer, J.; Sodt, A. J.; Storz, G.; Matthies, D.
10.1101/2024.02.28.582502 — biophysics — Posted on 2024-03-01