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Archive, 2022-11

2 Mincle-GSDMD-mediated release of IL-1β containing small extracellular vesicles contributes to ethanol-induced liver injury
Zhang, Q.; Liu, W.; Bulek, K.; Wang, H.; McMullen, M. R.; Wu, X.; Welch, N.; Zhang, R.; Dasarathy, J.; Srinivasan, D.; Laura, N.; Li, X.
10.1101/2022.11.30.518545 — immunology — Posted on 2022-11-30
3 Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
DeBlasi, J. M.; Falzone, A.; Caldwell, S.; Prieto-Farigua, N.; Prigge, J. R.; Schmidt, E. E.; Chio, I. I. C.; Karreth, F. A.; DeNicola, G. M.
10.1101/2022.08.24.504986 — cancer biology — Posted on 2022-11-30
6 Targeting of MMP-13 prevents aortic aneurysm formation in Marfan mice
Zimmermann, L.-M. A.; Furlan, A. G.; Mehrkens, D.; Geissen, S.; Zuk, A. V.; Pryymachuk, G.; Pykarek, N.; van Beers, T.; Sonntag-Bensch, D.; Marzi, J.; Schenke-Layland, K.; Brinckmann, J.; Grandoch, M.; Zigrino, P.; Baldus, S.; Sengle, G.
10.1101/2022.11.30.518511 — biochemistry — Posted on 2022-11-30
7 Transposable elements drive the evolution of metazoan zinc finger genes
Wells, J. N.; Chang, N.-C.; McCormick, J.; Coleman, C.; Ramos, N.; Jin, B.; Feschotte, C.
10.1101/2022.11.29.518450 — genomics — Posted on 2022-11-30
8 Detection of IL23p40 via Positron Emission Tomography Visualized Inflammatory Bowel Disease
Rezazadeh, F.; Ramos, N.; Saliganan, A.-D.; Al-Hallak, N.; Chen, K.; Mohamad, B.; Wiesend, W. N.; Viola, N. T.
10.1101/2022.11.30.518419 — molecular biology — Posted on 2022-11-30
9 Different low-complexity regions of SFPQ play distinct roles in the formation of biomolecular condensates
Marshall, A. C.; Cummins, J.; Kobelke, S.; Zhu, T.; Widagdo, J.; Anggono, V.; Hyman, A.; Fox, A. H.; Bond, C. S.; Lee, M.
10.1101/2022.11.30.518278 — molecular biology — Posted on 2022-11-30
11 Non-redundant dimethyl sulfoxide reductases influence Salmonella enterica serotype Typhimurium anaerobic growth and virulence
Cruz, E.; Haeberle, A. L.; Westerman, T. L.; Durham, M. E.; Suyemoto, M. M.; Knodler, L. A.; Elfenbein, J. R.
10.1101/2022.11.29.517730 — microbiology — Posted on 2022-11-30
12 Circadian regulation of human immunodeficiency virus type 1 replication
Borrmann, H.; Ulkar, G.; Kliszczak, A. E.; Ismed, D.; Schilling, M.; Magri, A.; Harris, J. M.; Balfe, P.; Vasudevan, S.; Borrow, P.; Zhuang, X.; McKeating, J. A.
10.1101/2022.11.30.518024 — microbiology — Posted on 2022-11-30
13 A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome.
Clerissi, C.; Luo, X.; Lucasson, A.; Mortaza, S.; de Lorgeril, J.; Toulza, E.; Petton, B.; Escoubas, J.-M.; Degremont, L.; Gueguen, Y.; Destoumieux Garzon, D.; Jacq, A.; Mitta, G.
10.1101/2020.11.16.384644 — microbiology — Posted on 2022-11-30
16 A 2.8A structure of zoliflodacin in a DNA-cleavage complex with Staphylococcus aureus DNA gyrase
Morgan, H.; Lipka-Lloyd, M.; Warren, A. J.; Hughes, N.; Holmes, J.; Burton, N. P.; Mahenthiralingam, E.; Bax, B. D.
10.1101/2022.11.30.518515 — biophysics — Posted on 2022-11-30
18 Mathematical modeling and biochemical analysis support partially ordered CaM-MLCK binding
MacEwen, M. J.; Rusnac, D. V.; Ermias, H.; Dexter, J. P.; Sancak, Y.; Locke, T. L. M.; Gizinski, H. E.
10.1101/2022.06.08.495195 — biochemistry — Posted on 2022-11-30
20 Temporal landscape of mitochondrial proteostasis governed by the UPRmt
Uoselis, L.; Lindblom, R.; Skulsuppaisarn, M.; Khuu, G.; Nguyen, T. N.; Rudler, D. L.; Filipovska, A.; Schittenhelm, R. B.; Lazarou, M.
10.1101/2022.11.30.518286 — cell biology — Posted on 2022-11-30
21 Regulation of replicative histone RNA metabolism by the histone chaperone ASF1
Almouzni, G.; Mendiratta, S.; Ray-Gallet, D.; Gatto, A.; Lemaire, S.; Kerlin, M. A.; Coulon, A.
10.1101/2022.11.30.518476 — molecular biology — Posted on 2022-11-30
24 Regulation of pSYSA defense plasmid copy number in Synechocystis through RNase E and a highly transcribed asRNA
Kaltenbrunner, A.; Reimann, V.; Hoffmann, U. A.; Aoyagi, T.; Sakata, M.; Nimura-Matsune, K.; Watanabe, S.; Steglich, C.; Wilde, A.; Hess, W. R.
10.1101/2022.11.30.518505 — microbiology — Posted on 2022-11-30
27 Origin and Evolution of Pseudomurein Biosynthetic Gene Clusters
Lupo, V.; Roomans, C.; Royen, E.; Ongena, L.; Jacquemin, O.; Kerff, F.; Baurain, D.
10.1101/2022.11.30.518518 — microbiology — Posted on 2022-11-30
32 FMRP phosphorylation modulates neuronal translation through YTHDF1
Zou, Z.; Wei, J.; Chen, Y.; Kang, Y.; Shi, H.; Yang, F.; Chen, S.; Zhou, Y.; Sepich-Poore, C.; Zhuang, X.; Zhou, X.; Jiang, H.; Wen, Z.; Jin, P.; Luo, C.; He, C.
10.1101/2022.11.29.518448 — molecular biology — Posted on 2022-11-30
33 Hematopoiesis and cell growth are differentially regulated by TAL1 isoforms
Sharma, A.; Mistriel-Zerbib, S.; Najar, R. A.; Engal, E.; Bentata, M.; Taqatqa, N.; Dahan, S.; Cohen, K.; Jaffe-Herman, S.; Geminder, O.; Baker, M.; Nevo, Y.; Plaschkes, I.; Kay, G.; Drier, Y.; Berger, M.; Salton, M.
10.1101/2022.11.30.518304 — molecular biology — Posted on 2022-11-30
34 Divergent and diversified proteome content across a serially acquired plastid lineage
Novak Vanclova, A. M. G.; Nef, C.; Vancl, A.; Liu, F.; Füssy, Z.; Bowler, C.; Dorrell, R. G.
10.1101/2022.11.30.518497 — microbiology — Posted on 2022-11-30
35 Translation-dependent downregulation of Cas12a mRNA by an anti-CRISPR protein
Marino, N. D.; Talaie, A.; Carion, H.; Zhang, Y.; Silas, S.; Li, Y.; Bondy-Denomy, J.
10.1101/2022.11.29.518452 — microbiology — Posted on 2022-11-30
37 SARS-CoV-2 Envelope-mediated Golgi pH dysregulation interferes with ERAAP retention in cells
Vargas-Zapata, V.; Geiger, K. M.; Tran, D.; Ma, J.; Mao, X.; Puschnik, A. S.; Coscoy, L.
10.1101/2022.11.29.518257 — cell biology — Posted on 2022-11-30
39 Rational strain design with minimal phenotype perturbation
Narayanan, B.; Weilandt, D. R.; Masid, M.; Miskovic, L.; Hatzimanikatis, V.
10.1101/2022.11.14.516382 — systems biology — Posted on 2022-11-30
40 Self-regulation of PIN1-driven auxin transport by cell surface-based auxin signaling in Arabidopsis
Wang, J.; Chang, M.; Huang, R.; Gallei, M.; Friml, J.; Yu, Y.; Wen, M.; Yang, Z.; Xu, T.
10.1101/2022.11.30.518523 — plant biology — Posted on 2022-11-30
45 High-resolution neural recordings improve the accuracy of speech decoding
Duraivel, S.; Rahimpour, S.; Chiang, C.-H.; Trumpis, M.; Wang, C.; Barth, K.; Lad, S. P.; Friedman, A. H.; Southwell, D. G.; Sinha, S. R.; Viventi, J.; Cogan, G. B.
10.1101/2022.05.19.492723 — neuroscience — Posted on 2022-11-30
46 Cell surface auxin signalling directly targets PIN-mediated auxin fluxes for adaptiveplant development
Rodriguez, L.; Fiedler, L.; Zou, M.; Giannini, C.; Monzer, A.; Gelova, Z.; Verstraeten, I.; Hajny, J.; Tan, S.; Hoermayer, L.; Li, L.; Marques-Bueno, M. M.; Molnar, G.; Xu, T.; Kulich, I.; Jaillais, Y.; Friml, J.
10.1101/2022.11.30.518503 — plant biology — Posted on 2022-11-30
48 FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
Wilde, B. R.; Chakraborty, N.; Matulionis, N.; Ueno, D.; Hernandez, S.; Esplin, E. D.; Ouyang, K.; Nykamp, K.; Shuch, B.; Christofk, H. R.
10.1101/2022.08.15.504023 — cancer biology — Posted on 2022-11-30
50 LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics
Ruffini, G.; Damiani, G.; Lozano-Soldevilla, D.; Deco, N.; Rosas, F.; Kiani, N.; Ponce-Alvarez, A.; Kringelbach, M. L.; Carhart-Harris, R.; Deco, G. L.
10.1101/2022.08.27.505518 — neuroscience — Posted on 2022-11-30
54 A Principal Odor Map Unifies Diverse Tasks in Human Olfactory Perception
Lee, B. K.; Mayhew, E. J.; Sanchez-Lengeling, B.; Wei, J. N.; Qian, W. W.; Little, K.; Andres, M.; Nguyen, B. B.; Moloy, T.; Parker, J. K.; Gerkin, R. C.; Mainland, J. D.; Wiltschko, A. B.
10.1101/2022.09.01.504602 — neuroscience — Posted on 2022-11-30
57 Time-Aligned Hourglass Gastrulation Models in Rabbit and Mouse
Mayshar, Y.; Raz, O.; Cheng, S.; Ben-Yair, R.; Hadas, R.; Reines, N.; Mittnenzweig, M.; Ben-Kiki, O.; Lifshitz, A.; Tanay, A.; Stelzer, Y.
10.1101/2022.11.13.516304 — evolutionary biology — Posted on 2022-11-30
59 Distinct feedforward and feedback pathways for cell-type specific attention effects
Spyropoulos, G.; Schneider, M.; van Kempen, J.; Gieselmann, M. A.; Thiele, A.; Vinck, M.
10.1101/2022.11.04.515185 — neuroscience — Posted on 2022-11-30
62 Contrasting genomic consequences of anthropogenic reintroduction and natural recolonisation in high-arctic wild reindeer
Burnett, H. A.; Bieker, V. C.; Le Moullec, M.; Peeters, B.; Rosvold, J.; Pedersen, A. O.; Dalen, L.; Loe, L. E.; Jensen, H.; Hansen, B. B.; Martin, M. D.
10.1101/2022.11.25.517957 — genomics — Posted on 2022-11-30
63 Membrane permeability differentiation at the lipid divide
Lapinska, U.; Glover, G.; Kahveci, Z.; Irwin, N.; Milner, D.; Tourte, M.; Albers, S.-V.; Santoro, A. E. S.; Richards, T. A.; Pagliara, S.
10.1101/2021.10.12.464042 — evolutionary biology — Posted on 2022-11-30
64 Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.
Kehrer, T.; Cupic, A.; Ye, C.; Yildiz, S.; Bouhhadou, M.; Crossland, N. A.; Barrall, E.; Cohen, P.; Tseng, A.; Cagatay, T.; Rathnasinghe, R.; Flores, D.; Jangra, S.; Alam, F.; Mena, N.; Aslam, S.; Saqi, A.; Marin, A.; Rutkowska, M.; Ummadi, M. R.; Pisanelli, G.; Richardson, R. B.; Veit, E. C.; Fabius, J. M. A.; Soucheray, M.; Polacco, B. J.; Evans, M. J.; Swaney, D. L.; Gonzalez-Reiche, A. S.; Sordillo, E. M.; van Bakel, H.; Simon, V.; Zuliani-Alvarez, L.; Fontoura, B. M. A.; Rosenberg, B. R.; Krogan, N. J.; Martinez-Sobrido, L.; Garcia-Sastre, A.; Miorin, L.
10.1101/2022.10.18.512708 — microbiology — Posted on 2022-11-30
65 A novel method to selectively elicit cold sensations without touch
Ezquerra-Romano, I.; Chowdhury, M.; Leone, C. M.; Iannetti, G.; Haggard, P.
10.1101/2022.06.14.496120 — neuroscience — Posted on 2022-11-30
68 Natural variability in bee brain size and symmetry revealed by micro-CT imaging and deep learning
Lösel, P. D.; Monchanin, C.; Lebrun, R.; Jayme, A.; Relle, J.; Devaud, J.-M.; Heuveline, V.; Lihoreau, M.
10.1101/2022.10.12.511944 — animal behavior and cognition — Posted on 2022-11-30
72 Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression
Grotehans, N.; McGarry, L.; Nolte, H.; Kroker, M.; Narbona-Perez, A. J.; Deshwal, S.; Giavalisco, P.; Langer, T.; MacVicar, T.
10.1101/2022.11.29.518352 — cell biology — Posted on 2022-11-30
78 PTEN-induced kinase 1 gene single-nucleotide variants as biomarkers in adjuvant chemotherapy for colorectal cancer
Mihara, Y.; Hirasaki, M.; Horita, Y.; Fujino, T.; Fukushima, H.; Kamakurab, Y.; Uranishi, K.; Hirano, Y.; Ryozawa, S.; Yasuda, M.; Makino, Y.; Shibasaki, S.; Hamaguchi, T.
10.1101/2022.11.28.518259 — cancer biology — Posted on 2022-11-30
79 Building Fluorescence Lifetime Maps Photon-by-photon by Leveraging Spatial Correlations
Fazel, M.; Jazani, S.; Scipioni, L.; Vallmitjana, A.; Zhu, S.; Gratton, E.; Digman, M.; Presse, S.
10.1101/2022.11.29.518311 — biophysics — Posted on 2022-11-30
80 A Possible Unitary Mechanism for General Anesthesia
Gupta, A.; Sang, Y.; Fontanesi, C.; Turin, L.; Naaman, R.
10.1101/2022.11.29.518334 — biophysics — Posted on 2022-11-30
81 Methylmap: visualization of modified nucleotides for large cohort sizes
Coopman, E.; Van den Broeck, M.; De Pooter, T.; Joris, G.; Dickson, D. W.; Strazisar, M.; Rademakers, R.; De Coster, W.
10.1101/2022.11.28.518239 — bioinformatics — Posted on 2022-11-30
83 Wet Adhesive Hydrogels to Correct Malacic Trachea (Tracheomalacia): A Proof of Concept
Uslu, E.; Rana, V.; Anagnostopoulos, S.; Karami, P.; Bergadano, A.; Courbon, C.; Gorostidi, F.; Sandu, K.; Stergiopulos, N.; Pioletti, D.
10.1101/2022.11.29.518329 — bioengineering — Posted on 2022-11-30
85 Comparative transcriptomics reveals divergent paths of chitinase evolution underlying dietary convergence in ant-eating mammals
Allio, R.; Teullet, S.; Lutgen, D.; Magdeleine, A.; Koual, R.; Tilak, M.-K.; de Thoisy, B.; Emerling, C. A.; Lefebure, T.; Delsuc, F.
10.1101/2022.11.29.518312 — evolutionary biology — Posted on 2022-11-30
87 Feline Coronavirus Infection of Domestic Cats Causes Development of Cross-Reactive Antibodies to SARS-CoV-2 Receptor Binding Domain
Yamamoto, J. K.; Edison, L. K.; Rowe-Haas, D. K.; Takano, T.; Glior, C.; Crews, C. D.; Tuanyok, A.; Arukha, A. P.; Shiomitsu, S.; Walden, H. D. S.; Hohdatsu, T.; Tompkins, S. M.; Morris, J. G.; Sahay, B.; Kariyawasam, S.
10.1101/2022.11.23.517619 — microbiology — Posted on 2022-11-30
90 Enhancing single-cell proteomics through tailored Data-Independent Acquisition and micropillar array-based chromatography
Petrosius, V.; Aragon-Fernandez, P.; Uresin, N.; Phlairaharn, T.; Furtwangler, B.; Op de Beeck, J.; Thomsen, S. F.; auf dem Keller, U.; Porse, B. T.; Schoof, E. M.
10.1101/2022.11.29.518366 — systems biology — Posted on 2022-11-30
91 Image-based quantification of Arabidopsis thaliana stomatal aperture from leaf images
Takagi, M.; Hirata, R.; Aihara, Y.; Hayashi, Y.; Aihara, M. M.; Ando, E.; Kono, M. Y.; Tomiyama, M.; Kinoshita, T.; Mine, A.; Toda, Y.
10.1101/2022.11.30.518467 — plant biology — Posted on 2022-11-30
94 Bimodal electroencephalography-functional magnetic resonance imaging dataset for inner-speech recognition
Simistira Liwicki, F.; Gupta, V.; Saini, R.; De, K.; Abid, N.; Rakesh, S.; Wellington, S.; Wilson, H.; Liwicki, M.; Eriksson, J.
10.1101/2022.05.24.492109 — neuroscience — Posted on 2022-11-30
97 Persulfidation of DJ-1 : Mechanism and Consequences
Galardon, E.; Mathas, N.; Padovani, D.; Le Corre, L.; Poncet, G.; Dairou, J.
10.1101/2022.11.09.515774 — biochemistry — Posted on 2022-11-30
98 Transcriptome responses of the aphid vector Myzus persicae are shaped by identities of the host plant and the virus
Chesnais, Q.; Golyaev, V.; Velt, A.; Rustenholz, C.; Verdier, M.; Brault, V.; Pooggin, M. M.; Drucker, M.
10.1101/2022.07.18.500449 — plant biology — Posted on 2022-11-30
100 Cell-surface protein YwfG of Lactococcus lactis binds to α-1,2-linked mannose
Tsuchiya, W.; Fujimoto, Z.; Inagaki, N.; Nakagawa, H.; Tanaka, M.; Kimoto-Nira, H.; Yamazaki, T.; Suzuki, C.
10.1101/2022.08.19.504583 — microbiology — Posted on 2022-11-30
103 AATF Inhibition Exerts Antiangiogenic Effects AgainstHuman Hepatocellular Carcinoma
S, D.; Srinivas, A. N.; Prashant, A.; Satish, S.; Vishwanath, P.; Santhekadur, P. K.; Kumar, D. P.
10.1101/2022.11.28.518287 — cancer biology — Posted on 2022-11-30
106 From primordial clocks to circadian oscillators
Pitsawong, W.; Padua, R. A.; Grant, T.; Hoemberger, M.; Otten, R.; Bradshaw, N.; Grigorieff, N.; Kern, D.
10.1101/2022.11.28.518275 — biochemistry — Posted on 2022-11-29
114 The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile
Auria, E.; Hunault, L.; ENGLAND, P.; Monot, M.; Pipoli Da Fonseca, J.; Matondo, M.; Duchateau, M.; Tremblay, Y. D.; Dupuy, B.
10.1101/2022.11.29.518320 — microbiology — Posted on 2022-11-29
116 An integrated resource for functional and structural connectivity of the marmoset brain
Tian, X.; Chen, Y.; Majka, P.; Szczupak, D.; Sanz-Perl, Y.; Yen, C. C.-C.; Tong, C.; Feng, F.; Jiang, H.; Glen, D.; Deco, G.; Rosa, M. G. P.; Silva, A. C.; Liang, Z.; Liu, C.
10.1101/2021.11.12.468389 — neuroscience — Posted on 2022-11-29
117 Next generation protein-based materials capture and preserve projectiles from supersonic impacts
Doolan, J. A.; Alesbrook, L. S.; Baker, K. B.; Brown, I. R.; Williams, G. T.; Hiscock, J. R.; Goult, B. T.
10.1101/2022.11.29.518433 — synthetic biology — Posted on 2022-11-29
118 PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
Nikolatou, K.; Sandilands, E.; Roman-Fernandez, A.; Cumming, E. M.; Freckmann, E. C.; Lilla, S.; Buetow, L.; McGarry, L.; Neilson, M.; Shaw, R.; Strachan, D.; Miller, C.; Huang, D. T.; McNeish, I. A.; Norman, J. C.; Zanivan, S.; Bryant, D.
10.1101/2022.11.29.518198 — cancer biology — Posted on 2022-11-29
123 Tissue- and sex-specific DNA damage tracks aging in rodents and humans
Guilbaud, A.; Ghanegolmohammadi, F.; Wang, Y.; Leng, J.; Kreymerman, A.; Gamboa Varela, J.; Garbern, J.; Elwell, H.; Cao, F.; Ricci-Blair, E. M.; Liang, C.; Balamkundu, S.; Vidoudez, C.; DeMott, M. S.; Bedi, K.; Margulies, K. B.; Bennett, D. A.; Palmer, A. A.; Barkley-Levenson, A.; Lee, R. T.; Dedon, P. C.
10.1101/2022.11.28.518087 — biochemistry — Posted on 2022-11-29
125 LSR Targets YAP to Modulate Intestinal Paneth Cell Differentiation
An, Y.; Wang, C.; Fan, B.; Li, Y.; Kong, F.; Zhou, C.; Cao, Z.; Liu, J.; Wang, M.; Sun, H.; Zhao, S.; Gong, Y.
10.1101/2022.10.30.514401 — developmental biology — Posted on 2022-11-29
126 Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2
Alonso-Gil, D.; Cuadrado, A.; Gimenez-Llorente, D.; Rodriguez-Corsino, M.; Losada, A.
10.1101/2022.11.29.518367 — cell biology — Posted on 2022-11-29
130 The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells
Chen, X.; Yang, H. T.; Zhang, B.; Phillips, J. W.; Cheng, D.; Rigo, F.; Witte, O. N.; Xing, Y.; Black, D. L.
10.1101/2022.11.29.518269 — molecular biology — Posted on 2022-11-29
133 Type I IFN signaling mediates NET release to promote Mycobacterium tuberculosis replication and granuloma caseation
Sur Chowdhury, C.; Kinsella, R. L.; Nehls, E. M.; Naik, S. K.; Lane, D. S.; Talukdar, P.; Chavez, S. M.; Smirnov, A.; Beatty, W.; Kreamalmeyer, D.; Mattila, J. T.; Stallings, C. L.
10.1101/2022.11.29.518376 — microbiology — Posted on 2022-11-29
134 Cell dichotomous role of STING in pulmonary hypertension
Pham, A. T.; Oliveira, A. C.; Fu, C.; Alves, M. D.; Dupee, Z.; Mukhsinova, L.; Ebrahimi, E.; Patel, H.; Patel, R.; Nguyen, A.; jin, l.; Bryant, A. J.
10.1101/2022.11.29.518422 — immunology — Posted on 2022-11-29
135 Gender impacts the relationship between mood disorder symptoms and effortful avoidance performance
Forys, B. J.; Tomm, R. J.; Stamboliyska, D.; Terpstra, A. R.; Clark, L.; Chakrabarty, T.; Floresco, S. B.; Todd, R. M.
10.1101/2022.06.21.497075 — neuroscience — Posted on 2022-11-29
137 Wikipedia as a tool for contemporary history of science: A case study on CRISPR
Benjakob, O.; Guley, O.; Sevin, J.-M.; Blondel, L.; Augustoni, A.; Collet, M.; Jouveshomme, L.; Amit, R.; Linder, A.; Aviram, R.
10.1101/2022.11.25.517950 — scientific communication and education — Posted on 2022-11-29
139 A general method for the development of multicolor biosensors with large dynamic ranges
Hellweg, L.; Edenhofer, A.; Barck, L.; Huppertz, M.-C.; Frei, M. S.; Tarnawski, M.; Bergner, A.; Koch, B.; Johnsson, K.; Hiblot, J.
10.1101/2022.11.29.518186 — biochemistry — Posted on 2022-11-29
141 Unappreciated Subcontinental Admixture in Europeans and European Americans: Implications for Genetic Epidemiology Studies
Gouveia, M. H.; Bentley, A. R.; Tarazona-Santos, E.; Bustamante, C. D.; Adeyemo, A. A.; Rotimi, C. R.; Shriner, D.
10.1101/2022.11.28.518227 — evolutionary biology — Posted on 2022-11-29
142 Localization of the pioneer factor GAF to subnuclear foci is driven by DNA binding and required to silence satellite repeat expression
Gaskill, M. M.; Soluri, I. V.; Branks, A. E.; Boka, A. P.; Stadler, M. R.; Vietor, K.; Huang, H.-Y. S.; Gibson, T. J.; Mir, M.; Blythe, S. A.; Harrison, M. M.
10.1101/2022.11.29.518380 — developmental biology — Posted on 2022-11-29
147 Identifying eukaryotes in drinking water metagenomes and factors influencing their biogeography.
Gabrielli, M.; Dai, Z.; Delafont, V.; Timmers, P.; van der Wielen, P.; Antonelli, M.; Pinto, A. J.
10.1101/2022.11.29.518372 — microbiology — Posted on 2022-11-29
151 Widespread, depth-dependent microstructural damage in the cortex of children with drug resistant focal epilepsy: A quantitative T1 and T2 mapping study
Casella, C.; Vecchiato, K.; Cromb, D.; Guo, Y.; Winkler, A. M.; Hughes, E.; Dillon, L.; Green, E.; Colford, K.; Egloff, A.; Siddiqui, A.; Price, A.; Cordero Grande, L.; Wood, T. C.; Malik, S.; Teixeira, R. P. A. G.; Carmichael, D. W.; O'Muircheartaigh, J.
10.1101/2022.11.29.518330 — neuroscience — Posted on 2022-11-29
153 Epigenetic and Signaling Determinants of Blood-Brain Barrier-Regulatory Genetic Networks
Pandit, P. K. T.; Sadanandan, J.; Thomas, S.; Mathew, I. E.; Huang, Z.; Blackburn, S. L.; Tandon, N.; Lokhande, H.; McCrea, P. D.; Bresnick, E. H.; Dash, P. K.; McBride, D. W.; Harmanci, A.; Jose, D.; Dienel, A. C.; Zeineddine, H. A.; Hong, S.
10.1101/2022.11.29.516809 — neuroscience — Posted on 2022-11-29
156 Compression supports low-dimensional representations of behavior across neural circuits
Zhou, D.; Kim, J. Z.; Pines, A. R.; Sydnor, V. J.; Roalf, D. R.; Detre, J. A.; Gur, R. C.; Gur, R. E.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2022.11.29.518415 — neuroscience — Posted on 2022-11-29
160 Endozoicomonas-chlamydiae interactions in cell-associated microbial aggregates of the coral Pocillopora acuta
Maire, J.; Tandon, K.; Collingro, A.; van de Meene, A.; Damjanovic, K.; Gotze, C. R.; Stephenson, S.; Philip, G. K.; Horn, M.; Cantin, N. E.; Blackall, L. L.; van Oppen, M. J. H.
10.1101/2022.11.28.517745 — microbiology — Posted on 2022-11-29
161 SARS-CoV-2 Vaccine Booster Elicits Robust Prolonged Maternal Antibody Responses and Passive Transfer Via The Placenta And Breastmilk
Marshall, N. E.; Blanton, M. B.; Doratt, B. M.; Malherbe, D. C.; Rincon, M.; True, H.; McDonald, T.; Beauregard, C.; Adatorwovor, R.; Messaoudi, I.
10.1101/2022.11.29.518385 — immunology — Posted on 2022-11-29
162 Host genetic background is a barrier to broadly effective vaccine protection: Relevance to BCG and Mycobacterium tuberculosis Infection
Lai, R.; Gong, D.; Williams, T.; Ogunsola, A. F.; Cavallo, K.; Arlehamn, C. L.; Beamer, G.; Ferris, M.; Sassetti, C. M.; Lauffenburger, D.; Behar, S.
10.1101/2022.09.19.508548 — immunology — Posted on 2022-11-29
166 Design principles of caveolins across metazoa and beyond
Han, B.; Wilson, L. F. L.; Gulsevin, A.; Meiler, J.; Karakas, E.; Kenworthy, A. K.
10.1101/2022.11.15.516482 — biophysics — Posted on 2022-11-29
167 Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Methyltransferases
Gericke, L.; Karst, L. C.; Mhaindarkar, D.; Jahn, S.; Kuge, M.; Mohr, M. K. F.; Gagsteiger, J.; Cornelissen, N. V.; Wen, X.; Mordhorst, S.; Jessen, H.; Rentmeister, A.; Seebeck, F. P.; Layer, G.; Loenarz, C.; Andexer, J. N.
10.1101/2022.09.26.509380 — biochemistry — Posted on 2022-11-29
169 Global determinants of insect genetic diversity
French, C. M.; Bertola, L. D.; Carnaval, A. C.; Economo, E. P.; Kass, J. M.; Lohman, D. J.; Marske, K. A.; Meier, R.; Overcast, I.; Rominger, A. J.; Staniczenko, P.; Hickerson, M. J.
10.1101/2022.02.09.479762 — evolutionary biology — Posted on 2022-11-29
174 ApoE isoforms differentially regulate neuronal membrane proteasomes to shift the threshold for pathological aggregation of endogenous Tau
Paradise, V.; Sabu, M.; Bafia, J.; Sharif, N. A.; Nguyen, C.; Dhanraj Mukim, R.; Wang, X.; Fu, J.; Ndubisi, J.; Maldonado, G.; Strickland, M.; Figueroa, H.; Almeida, D. L.; Hyman, B. T.; Holtzman, D. M.; Nuriel, T.; Ramachandran, K. V.
10.1101/2022.11.29.518293 — neuroscience — Posted on 2022-11-29
177 Bioschemas Training Profiles: A set of specifications for standardizing training information to facilitate the discovery of training programs and resources
Jael Castro, L.; Palagi, P. M.; Beard, N.; Bioschemas Training Profiles Group Members, ; ELIXIR FAIR Training Focus Group, ; The GOBLET Foundation, ; Attwood, T. K.; Brazas, M. D.
10.1101/2022.11.24.516513 — scientific communication and education — Posted on 2022-11-29
179 Remodelled Ribosomes Synthesise a Specific Proteome in Proliferating Plant Tissue during Cold
Martinez-Seidel, F.; Suwanchaikasem, P.; Gentry-Torfer, D.; Rajarathinam, Y.; Ebert, A.; Erban, A.; Firmino, A. A.; Nie, S.; Leeming, M. G.; Williamson, N. A.; Roessner, U.; Kopka, J.; Boughton, B. A.
10.1101/2022.11.28.518201 — plant biology — Posted on 2022-11-29
185 Brewpitopes: a pipeline to refine B-cell epitope predictions during public health emergencies
Farriol-Duran, R.; Lopez-Aladid, R.; Porta-Pardo, E.; Torres, A.; Fernandez-Barat, L.
10.1101/2022.11.28.518301 — bioinformatics — Posted on 2022-11-29
186 Reducing the foreign body response on human cochlear implants and their materials in vivo with photografted zwitterionic hydrogel coatings
Horne, R. R.; Ben-Shlomo, N.; Jensen, M.; Ellerman, M.; Escudero, C.; Hua, R. Z.; Bennion, D.; Guymon, C. A.; Hansen, M. R.
10.1101/2022.11.28.518125 — bioengineering — Posted on 2022-11-29
194 Endozoicomonas-chlamydiae interactions in cell-associated microbial aggregates of the coral Pocillopora acuta
Maire, J.; Tandon, K.; Collingro, A.; van de Meene, A.; Damjanovic, K.; Gotze, C. R.; Stephenson, S.; Philip, G. K.; Horn, M.; Cantin, N. E.; Blackall, L. L.; van Oppen, M. J. H.
10.1101/2022.11.28.517745 — microbiology — Posted on 2022-11-29
195 Structural Elucidation of a Protective B cell Epitope on Outer Surface Protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi
Rudolph, M. J.; Davis, S.; Haque, H. M. E.; Weis, D. D.; Vance, D. J.; Piazza, C. L.; Ejemel, M.; Cavacini, L. A.; Wang, Y.; Mbow, L.; Gilmore, R. D.; Mantis, N. J.
10.1101/2022.11.28.518297 — immunology — Posted on 2022-11-29
196 Structural and Computational Design of a SARS-CoV-2 Spike Antigen with Increased Receptor Binding Domain Exposure and Improved Immunogenicity
Williams, J.; Biancucci, M.; Lessen, L.; Tian, S.; Balsaraf, A.; Chen, L.; Chesterman, C.; Maruggi, G.; Vandepaer, S.; Huang, Y.; Mallett, C.; Steff, A.-M.; Bottomley, M.; Malito, E.; Wahome, N.; Harshbarger, W.
10.1101/2022.11.29.518231 — immunology — Posted on 2022-11-29
197 Myeloid-specific KDM6B inhibition sensitizes Glioblastoma to PD1 blockade
Goswami, S.; Raychaudhuri, D.; Singh, P.; Natarajan, S. M.; Chen, Y.; Poon, C.; Hennessey, M.; Zhang, J.; Anandhan, S.; Kerrigan, B. P.; Macaluso, M. D.; He, Z.; Jindal, S.; Lang, F. F.; Basu, S.; Sharma, P.
10.1101/2022.11.28.518243 — immunology — Posted on 2022-11-29
199 Experience Adaptively Tunes the Timing Rules for Associative Plasticity
Jayabal, S.; Bhasin, B. J.; Suvrathan, A.; DiSanto, J.; Goldman, M. S.; Raymond, J. L.
10.1101/2022.11.28.518128 — neuroscience — Posted on 2022-11-29
200 Non-invasive diagnostic method to objectively measure olfaction and diagnose smell disorders by molecularly targeted fluorescent imaging agent
Adilbay, D.; Gonzales, J.; Zazhytska, M.; Demetrio de Souza Franca, P.; Roberts, S.; Viray, T.; Artschwager, R.; Patel, S.; Kodra, A.; Overdevest, J. B.; Chow, C. Y.; King, G. F.; Jain, S. K.; Ordonez, A. A.; Caroll, L. S.; Reiner, T.; Pillarsetty, N.
10.1101/2021.10.07.463532 — neuroscience — Posted on 2022-11-29
202 Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development
Schonke, M.; Ying, Z.; Kovynev, A.; In het Panhuis, W.; Binnendijk, A.; van der Poel, S.; Pronk, A. C. M.; Streefland, T. C. M.; Hoekstra, M.; Kooijman, S.; Rensen, P. C. N.
10.1101/2022.11.28.518180 — physiology — Posted on 2022-11-29
203 Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant SMO and GLI into Glioma Primary Cilia
Shi, P.; Tian, J.; Mallinger, J.; Deleyrolle, L.; McIntyre, J.; Caspary, T.; Breunig, J.; Sarkisian, M. R.
10.1101/2022.11.28.518234 — cancer biology — Posted on 2022-11-29
207 Rethinking bacterial relationships in light of their molecular abilities
Mahlich, Y.; Zhu, C.; Chung, H.; Velaga, P. K.; de Paolis Kaluza, M. C.; Radivojac, P.; Friedberg, I.; Bromberg, Y.
10.1101/2022.11.28.518265 — bioinformatics — Posted on 2022-11-29
209 Soft and stretchable organic bioelectronics for continuous intra-operative neurophysiological monitoring during microsurgery
Zhou, W.; Jiang, Y.; Xu, Q.; Chen, L.; Qiao, H.; Wang, Y.-X.; Lai, J.-C.; Zhong, D.; Zhang, Y.; Li, W.; Du, Y.; Wang, X.; Lei, J.; Dong, G.; Guan, X.; Ma, S.; Kang, P.; Yuan, L.; Zhang, M.; Tok, J. B. H.; Li, D.; Bao, Z.; Jia, W.
10.1101/2022.11.28.518170 — bioengineering — Posted on 2022-11-29
210 From primordial clocks to circadian oscillators
Pitsawong, W.; Padua, R. A.; Grant, T.; Hoemberger, M.; Otten, R.; Bradshaw, N.; Grigorieff, N.; Kern, D.
10.1101/2022.11.28.518275 — biochemistry — Posted on 2022-11-29
211 Tissue- and sex-specific DNA damage tracks aging in rodents and humans
Guilbaud, A.; Ghanegolmohammadi, F.; Wang, Y.; Leng, J.; Kreymerman, A.; Gamboa Varela, J.; Garbern, J.; Elwell, H.; Cao, F.; Ricci-Blair, E. M.; Liang, C.; Balamkundu, S.; Vidoudez, C.; DeMott, M. S.; Bedi, K.; Margulies, K. B.; Bennett, D. A.; Palmer, A. A.; Barkley-Levenson, A.; Lee, R. T.; Dedon, P. C.
10.1101/2022.11.28.518087 — biochemistry — Posted on 2022-11-29
212 SapBase (Sapinaceae Genomic DataBase): a central portal for functional and comparative genomics of Sapindaceae species
Li, J.; Chen, C.; Zeng, Z.; Wu, F.; Feng, J.; Liu, B.; Mai, Y.; Chu, X.; Wei, W.; Li, X.; Liang, Y.; Liu, Y.; Xu, J.; Xia, R.
10.1101/2022.11.25.517904 — genomics — Posted on 2022-11-29
213 A draft genome of the ascomycotal fungal species Pseudopithomyces maydicus (family Didymosphaeriaceae)
Arumugam, K.; Ho, S.; Bessarab, I.; Goh, F. Q. Y.; Haryono, M. A. S.; Santillan, E.; Wuertz, S.; Chow, Y.; Williams, R. B. H.
10.1101/2022.11.26.518055 — genomics — Posted on 2022-11-29
214 Extensive somatic nuclear exchanges shape global populations of the wheat leaf rust pathogen Puccinia triticina
Sperschneider, J.; Hewitt, T.; Lewis, D.; Periyannan, S.; Milgate, A.; Hickey, L.; Mago, R.; Dodds, P.; Figueroa, M.
10.1101/2022.11.28.518271 — genomics — Posted on 2022-11-29
221 Polyethylene glycol (PEG)-associated immunological effects triggered by clinically relevant lipid nanoparticles
Wang, H.; Wang, Y.; Yuan, C.; Xu, X.; Zhou, W.; Huang, Y.; Lu, H.; Zheng, Y.; Luo, G.; Shang, J.; Sui, M.
10.1101/2022.11.24.516986 — immunology — Posted on 2022-11-29
222 Macrophage and neutrophil heterogeneity at single-cell spatial resolution in inflammatory bowel disease
Garrido-Trigo, A.; Corraliza, A.; Veny, M.; Dotti, I.; Melon-Ardanaz, E.; Rill, A.; Crowell, H. L.; Corbi, A.; Gudino, V.; Esteller, M.; Alvarez-Teubel, I.; Aguilar, D.; Masamunt, M. C.; Killingbeck, E.; Kim, Y.; Leon, M.; Visvanathan, S.; Marchese, D.; Caratu, G.; Martin-Cardona, A.; Esteve, M.; Panes, J.; Ricart, E.; Mereu, E.; Heyn, H.; Salas, A.
10.1101/2022.11.28.518139 — immunology — Posted on 2022-11-29
223 Multivalent Human Cytomegalovirus Glycoprotein B Nucleoside-Modified mRNA Vaccines Demonstrate a Greater Breadth in T cell but not Antibody Responses
Permar, S. R.; Wang, H.-Y.; Li, L.; Nelson, C. S.; Barfield, R.; Valencia, S.; Chan, C.; Muramatsu, H.; Lin, P. J. C.; Pardi, N.; An, Z.; Weissman, D.
10.1101/2022.11.23.517695 — immunology — Posted on 2022-11-29
224 Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis
Patterson, M. T.; Firulyova, M. M.; Xu, Y.; Bishop, C.; Zhu, A.; Schrank, P. R.; Ronayne, C. E.; Fredrickson, G.; Kennedy, A. E.; Acharya, N.; Revelo, X.; Stromnes, I. M.; Bold, T. D.; Zaitsev, K.; Williams, J. W.
10.1101/2022.11.28.518255 — immunology — Posted on 2022-11-29
230 Deep Learning Allows Assessment of Risk of Metastatic Relapse from Invasive Breast Cancer Histological Slides
Garberis, I.; Gaury, V.; Saillard, C.; Drubay, D.; Elgui, K.; Schmauch, B.; Jaeger, A.; Herpin, L.; Linhart, J.; Sapateiro, M.; Bernigole, F.; Kamoun, A.; Bendjebbar, E.; de Lavergne, A.; Dubois, R.; Auffret, M.; Guillou, L.; Bousaid, I.; Azoulay, M.; Lemonnier, J.; Sefta, M.; Jacquet, A.; Sarrazin, A.; Reboud, J.-F.; Brulport, F.; Dachary, J.; Pistilli, B.; Delaloge, S.; Courtiol, P.; Andre, F.; Aubert, V.; Lacroix-Triki, M.
10.1101/2022.11.28.518158 — pathology — Posted on 2022-11-29
231 T-cell receptor specific protein language model for prediction and interpretation of epitope binding (ProtLM.TCR)
Essaghir, A.; Sathiyamoorthy, N. K.; Smyth, P.; Postelnicu, A.; Ghiviriga, S.; Ghita, A.; Singh, A.; Kapil, S.; Phogat, S.; Singh, G.
10.1101/2022.11.28.518167 — bioinformatics — Posted on 2022-11-29
235 Phylogeographic reconstruction of the emergence and spread of Powassan virus in the northeastern United States
Vogels, C. B. F.; Brackney, D. E.; Dupuis, A. P.; Robich, R. M.; Fauver, J. R.; Brito, A. F.; Williams, S. C.; Anderson, J. F.; Lubelczyk, C. B.; Lange, R. E.; Prusinski, M. A.; Kramer, L. D.; Gangloff-Kaufmann, J. L.; Goodman, L. B.; Baele, G.; Smith, R. P.; Armstrong, P. M.; Ciota, A. T.; Dellicour, S.; Grubaugh, N. D.
10.1101/2022.10.14.512245 — genomics — Posted on 2022-11-29
239 Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation
Ilamathi, H. S.; Benhammouda, S.; Lounas, A.; Al-Naemi, K.; Desrochers-Goyette, J.; Lines, M. A.; Richard, F.; Vogel, J.; Germain, M.
10.1101/2021.12.09.472002 — cell biology — Posted on 2022-11-29
240 Landscape-scale exposure to multiazole-resistant Aspergillus fumigatus bioaerosols
Shelton, J. M. G.; Rhodes, J.; Uzzell, C. B.; Hemmings, S.; Brackin, A. P.; Sewell, T. R.; Alghamdi, A.; Dyer, P. S.; Fraser, M.; Borman, A. M.; Johnson, E. M.; Piel, F. B.; Singer, A. C.; Fisher, M.
10.1101/2022.11.07.515445 — microbiology — Posted on 2022-11-29
241 Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Rouet, R.; Henry, J. Y.; Johansen, M. D.; Sobti, M.; Balachandran, H.; Langley, D. B.; Walker, G.; Lenthall, H.; Jackson, J.; Ubiparipovic, S.; Mazigi, O.; Schofield, P.; Burnett, D. L.; Brown, S. H. J.; Martinello, M.; Hudson, B.; Gilroy, N.; Post, J. J.; Kelleher, A.; Jäck, H.-M.; Goodnow, C.; Turville, S. G.; Rawlinson, W. D.; Bull, R. A.; Stewart, A. G.; Hansbro, P. M.; Christ, D.
10.1101/2022.10.19.512954 — immunology — Posted on 2022-11-29
243 Single-cell Mendelian randomisation identifies cell-type specific genetic effects on human brain disease and behaviour
Haglund, A.; Zuber, V.; Yang, Y.; Abouzeid, M.; Feleke, R.; Ko, J.-H.; Nott, A.; Babtie, A. C.; Mills, J. D.; Muhammed, L.; Laaniste, L.; Gveric, D. O.; Clode, D.; Pagni, S.; Bellampalli, R.; Somani, A.; McDade, K.; Anink, J. J.; Mesarosova, L.; Aronica, E.; Thom, M.; Sisodiya, S. M.; Srivastava, P. K.; Malhotra, D.; Bryois, J.; Bottolo, L.; Johnson, M. R.
10.1101/2022.11.28.517913 — neuroscience — Posted on 2022-11-29
249 A semi-supervised Bayesian mixture modelling approach for joint batch correction and classification
Coleman, S.; Nicholls, K. C.; Castro Dopico, X.; Karlsson Hedestam, G. B.; Kirk, P. D.; Wallace, C.
10.1101/2022.01.14.476352 — bioinformatics — Posted on 2022-11-29
250 NetworkExtinction: an R package to simulate extinction's propagation and rewiring potential in ecological networks
Avila-Thieme, M. I.; Corcoran, D.; Kusch, E.; Castillo, S. P.; Valdovinos, F. S.; Navarrete, S. A.; Marquet, P. A.
10.1101/2020.10.17.305391 — ecology — Posted on 2022-11-29
253 Eosinophilic esophagitis-associated epithelial remodeling may limit esophageal carcinogenesis
Fuller, A. D.; Karami, A. L.; Kabir, M. F.; Klochkova, A.; Jackson, J. L.; Mu, A.; Tan, Y.; Klein-Szanto, A.; Whelan, K. A.
10.1101/2022.11.28.517589 — cell biology — Posted on 2022-11-29
254 Structural and functional specializations of human fast spiking neurons support fast cortical signaling
Wilbers, R.; Galakhova, A. A.; Heistek, T. S.; Metodieva, V. D.; Hagemann, J.; Heyer, D. B.; Mertens, E. J.; Deng, S.; Idema, S.; de Witt Hamer, P. C.; Noske, D. P.; van Schie, P.; Kommers, I.; Luan, G.; Li, T.; Shu, Y.; de Kock, C. P. J.; Mansvelder, H. D.; Goriounova, N. A.
10.1101/2022.11.29.518193 — neuroscience — Posted on 2022-11-29
255 Signatures of electrical stimulation driven network interactions in the human limbic system
Ojeda Valencia, G.; Gregg, N. M.; Worrell, G. A.; Huang, H.; Lundstrom, B.; Brinkmann, B.; Pal Attia, T.; Van Gompel, J.; Bernstein, M. A.; In, M.-H.; Huston, J. I.; Miller, K. J.; Hermes, D.
10.1101/2022.11.23.517746 — neuroscience — Posted on 2022-11-29
258 Population-level integration of single-cell datasets enables multi-scale analysis across samples
De Donno, C.; Hediyeh-Zadeh, S.; Wagenstetter, M.; Moinfar, A. A.; Zappia, L.; Lotfollahi, M.; Theis, F. J.
10.1101/2022.11.28.517803 — genomics — Posted on 2022-11-29
260 Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC- βH5 beta cells
Frorup, C.; Gerwig, R.; Sondergaard Svane, C. A.; Mendes Lopes de Melo, J.; Floyel, T.; Pociot, F.; Kaur, S.; Storling, J.
10.1101/2022.11.29.518315 — cell biology — Posted on 2022-11-29
262 Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signalling pathway
Dulloo, I.; Tellier, M.; Levet, C.; Chikh, A.; Zhang, B.; Webb, C. M.; Kelsell, D. P.; Freeman, M.
10.1101/2022.11.28.518246 — cell biology — Posted on 2022-11-29
263 Utilization of an Artery-on-a-chip to unravel novel regulators and therapeutic targets in vascular diseases
Paloschi, V.; Pauli, J.; Winski, G.; Wu, Z.; Li, Z.; Glukha, N.; Hummel, N.; Rogowitz, R.; Meucci, S.; Botti, L.; Busch, A.; Chernogubova, E.; Jin, H.; Sachs, N.; Eckstein, H.-H.; Boon, R. A.; Bausch, A. R.; Maegdefessel, L.
10.1101/2022.11.29.517312 — cell biology — Posted on 2022-11-29
264 The human sperm head spins with a conserved direction during swimming in 3D
Corkidi, G.; Montoya, F.; Gonzalez-Cota, A. L.; Hernandez-Herrera, P.; Bruce, N. C.; Bloomfield-Gadelha, H.; Darszon, A.
10.1101/2022.11.28.517870 — cell biology — Posted on 2022-11-29
265 Aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk
Goody, P. R.; Christmann, D.; Goody, D.; Nehl, D.; Backer, K.; Wilhelm-Juengling, K.; Uchida, S.; Moore, J. B.; Zimmer, S.; Bakhtiary, F.; Pfeifer, A.; Latz, E.; Nickenig, G.; Jansen, F.; Hosen, M. R.
10.1101/2022.11.29.518326 — cell biology — Posted on 2022-11-29
266 Oxygen is a critical regulator of cellular metabolism and function in cell culture
Tan, J.; Virtue, S.; Norris, D. M.; Conway, O. J.; Yang, M.; Gribben, C.; Lutgu, F.; Krycer, J. R.; Mills, R. J.; Kamzolas, I.; Pereira, C.; Dale, M.; Shun-Shion, A. S.; Baird, H. J.; Horscroft, J. A.; Sowton, A. P.; Ma, M.; Carobbio, S.; Petsalaki, E.; Murray, A. J.; Gershlick, D. C.; Hudson, J. E.; Vallier, L.; Fisher-Wellman, K. H.; Frezza, C.; Vidal-Puig, A.; Fazakerley, D. J.
10.1101/2022.11.29.516437 — cell biology — Posted on 2022-11-29
268 Spatial scale influences taxon conservation in the eukaryotic virome of a mosquito
Gil, P.; Exbrayat, A.; Loire, E.; Rakotoarivoany, I.; Charriat, F.; Baldet, T.; Boisseau, M.; Marie, A.; Frances, B.; L'Ambert, G.; Bessat, M.; Otify, Y.; Goffredo, M.; Mancini, G.; Busquets, N.; Birnberg, L.; Talavera, S.; Aranda, C.; Ayari-Fakhfakh, E. S.; Mejri, S.; Sghaier, S.; Bennouna, A.; El Rhaffouli, H.; Balenghien, T.; Chlyeh, G.; Fihri, O. F.; Reveillaud, J.; Simonin, Y.; Eloit, M.; Gutierrez, S.
10.1101/2022.11.23.517782 — ecology — Posted on 2022-11-29
270 Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Sampedro-Castaneda, M.; Baltussen, L. L.; Lopes, A. T.; Qiu, Y.; Sirvio, L.; Mihaylov, S. R.; Claxton, S.; Richardson, J. C.; Lignani, G.; Ultanir, S. K.
10.1101/2022.11.24.517538 — neuroscience — Posted on 2022-11-29
272 Comparative genomic analysis between Leonurus japonicus and Leonurus sibiricus
Yang, D.-j.; Yan, M.-x.; Li, P.; Liu, P.; Gao, Y.; Jiang, Y.; He, Z.-k.; Zhong, X.; Wu, S.; Kong, Y.; Yang, J.; Wang, H.-x.; Huang, Y.-b.; Wang, L.; Chen, X.-y.; Hu, Y.-h.; Zhao, Q.; Xu, P.
10.1101/2022.11.27.518111 — plant biology — Posted on 2022-11-29
274 Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands
Fierro, F.; Peri, L.; Huebner, H.; Tabor-Schkade, A.; Waterloo, L.; Loeber, S.; Pfeiffer, T.; Weikert, D.; Dingjan, T.; Margulis, E.; Gmeiner, P.; Niv, M. Y.
10.1101/2022.11.24.517821 — bioinformatics — Posted on 2022-11-29
275 A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma
Sidik, S.; Valleau, D.; Acevedo-Sanchez, Y.; Godoy, L. C.; Pasaje, C. F. A.; Huynh, M.-H.; Carruthers, V. B.; Niles, J. C.; Lourido, S.
10.1101/2022.11.28.518173 — microbiology — Posted on 2022-11-29
277 Fc-gamma receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2
Mackin, S. R.; Desai, P.; Whitener, B. M.; Karl, C. E.; Liu, M.; Baric, R. S.; Edwards, D. K.; Chicz, T. M.; McNamara, R. P.; Alter, G.; Diamond, M. S.
10.1101/2022.11.27.518117 — microbiology — Posted on 2022-11-29
283 Whole genome sequencing reveals fine-scale climate associated adaptive divergence near the range limits of a temperate reef fish.
Nugent, C. M.; Kess, T.; Brachmann, M. K.; Langille, B. L.; Duffy, S.; Lehnert, S. J.; Wringe, B.; Bentzen, P.; Bradbury, I. R.
10.1101/2022.11.28.517507 — genomics — Posted on 2022-11-28
288 Caught in the Act: targeted mutagenesis of the herpesvirus fusogen central helix captures transition states
Zhou, M.; Vollmer, B.; Machala, E.; Chen, M.; Grünewald, K.; Arvin, A. M.; Chiu, W.; Oliver, S. L.
10.1101/2022.11.23.517751 — microbiology — Posted on 2022-11-28
293 Glucose modulates transcription factor dimerization to enable tissue differentiation
Lopez-Pajares, V.; Bhaduri, A.; Zhao, Y.; Gowrishankar, G.; Donohue, L.; Guo, M. G.; Siprashvili, Z.; Miao, W.; Nguyen, D. T.; Li, A. M.; Shanderson, R. L.; Meyers, R. M.; Guerrero, A.; Garcia, O. S.; Tao, S.; Meservey, L. M.; Yang, X.; Gambhir, S. S.; Ye, J.; Khavari, P. A.
10.1101/2022.11.28.518222 — molecular biology — Posted on 2022-11-28
294 Mitotic bookmarking redundancy by nuclear receptors mediates robust post-mitotic reactivation of the pluripotency network.
Chervova, A.; Molliex, A.; Baymaz, I.; Papadopolou, T.; Mueller, F.; Hercul, E.; Fournier, D.; Dubos, A.; Gaiani, N.; Beli, P.; Festuccia, N.; Navarro, P.
10.1101/2022.11.28.518105 — molecular biology — Posted on 2022-11-28
299 CSF1R inhibitor levels determine sex-specific phenotype of resilient microglia and neurofunctional rescue leading to extended survival in tauopathy mice
Johnson, N. R.; Yuan, P.; Castillo, E.; Lopez, T. P.; Yue, W.; Bond, A.; Rivera, B. M.; Sullivan, M. C.; Hirouchi, M.; Giles, K.; Aoyagi, A.; Condello, C.
10.1101/2021.03.20.436288 — neuroscience — Posted on 2022-11-28
300 Cacna2d2 is an hnRNP H target of the striatal mRNA targetome and regulates methamphetamine behavior
Ruan, Q. T.; Lynch, W. B.; Cole, R. H.; Rieger, M. A.; Beierle, J. A.; Yao, E. J.; Cox, J. W.; Kandola, A.; Richardson, K. T.; Chen, M. M.; Kelliher, J. C.; Babbs, R. K.; Ash, P. E. A.; Wolozin, B.; Szumlinski, K. K.; Johnson, W. E.; Dougherty, J.; Bryant, C. D.
10.1101/2021.07.06.451358 — neuroscience — Posted on 2022-11-28
302 Molecular machines stimulate intercellular calcium waves and cause muscle contraction
Beckham, J. L.; van Venrooy, A. R.; Kim, S.; Li, G.; Li, B.; Duret, G.; Arnold, D.; Zhao, X.; Santos, A. L.; Chaudhry, G.; Robinson, J. T.; Tour, J.
10.1101/2022.11.04.515191 — bioengineering — Posted on 2022-11-28
305 Selection-driven trait loss in independently evolved cavefish populations
Moran, R. L.; Richards, E. J.; Ornelas-Garcia, C. P.; Gross, J. B.; Donny, A.; Wiese, J.; Keene, A. C.; Kowalko, J. E.; Rohner, N.; McGaugh, S. E.
10.1101/2022.11.28.518185 — evolutionary biology — Posted on 2022-11-28
308 The human-specific miR-6762-5p is an activator of RhoA GTPase enhancing Shigella flexneri intercellular spreading
Reisacher, C.; Saifi, E.; Ageron-Ardila, E.; Mallmann, R. T.; Klugbauer, N.; Skurnik, D.; Arbibe, L.
10.1101/2022.11.28.518194 — microbiology — Posted on 2022-11-28
312 Resilient CD8+ T cells maintain a high cytotoxic capacity by balancing ROS via ME1 upregulation
Gicobi, J. K.; Mao, Z.; DeFranco, G.; Li, Y.; Liu, C.; Hirdler, J. B.; Vianzon, V. V.; Dellacecca, E. R.; Hsu, M. A.; Barham, W.; Kim, Y. H.; Feven, A.; Harmsen, W. S.; Yan, Y.; Dronca, R. S.; Zhu, M.; Markovic, S.; Mansfield, A. S.; Lin, Y.; Wu, X.; Owen, D.; Grams, M. P.; Orme, J. J.; Lucien, F.; Zeng, H.; Park, S. S.; Dong, H.
10.1101/2022.11.25.517988 — immunology — Posted on 2022-11-28
314 Single-cell Mendelian randomisation identifies cell-type specific genetic effects on human brain disease and behaviour
Haglund, A.; Zuber, V.; Yang, Y.; Abouzeid, M.; Feleke, R.; Ko, J.-H.; Nott, A.; Babtie, A. C.; Mills, J. D.; Muhammed, L.; Laaniste, L.; Gveric, D. O.; Clode, D.; Pagni, S.; Bellampalli, R.; Somani, A.; McDade, K.; Anink, J. J.; Mesarosova, L.; Aronica, E.; Thom, M.; Sisodiya, S. M.; Srivastava, P. K.; Malhotra, D.; Bryois, J.; Bottolo, L.; Johnson, M. R.
10.1101/2022.11.28.517913 — neuroscience — Posted on 2022-11-28
319 Mitochondrial Pyruvate Carrier Inhibition Initiates Metabolic Crosstalk to Stimulate Branched Chain Amino Acid Catabolism
Ferguson, D.; Eichler, S. J.; Yiew, N. K. H.; Colca, J. R.; Cho, K.; Lutkewitte, A. J.; Patti, G. J.; McCommis, K. S.; Niemi, N. M.; Finck, B. N.
10.1101/2022.05.11.491550 — physiology — Posted on 2022-11-28
320 Transcriptional signals of dedifferentiation in human cancer
Kildisiute, G.; Kalyva, M.; Elmentaite, R.; van Dongen, S.; Thevanesan, C.; Piapi, A.; Ambridge, K.; Prigmore, E.; Haniffa, M.; Teichmann, S. A.; Straathof, K.; Cortes-Ciriano, I.; Behjati, S.; Young, M. D.
10.1101/2022.11.28.518191 — cancer biology — Posted on 2022-11-28
322 Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures
Bucki, R.; Iwamoto, D.; Shi, X.; Kerr, K. E.; Byfield, F. J.; Suprewicz, L.; Sklodowski, K.; Sutaria, J.; Misiak, P.; Wilczewska, A.; Ramachandran, S.; Wolfe, A.; Thanh, M.-T. H.; Whalen, E.; Patteson, A. E.; Janmey, P.
10.1101/2022.11.28.518249 — biophysics — Posted on 2022-11-28
323 Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells
Dong, W.; Keibler, M. A.; Moon, S. J.; Cho, P.; Liu, N.; Berrios, C. J.; Kelleher, J.; Sikes, H. D.; Iliopoulos, O.; Coloff, J.; Vander Heiden, M.; Stephanopoulos, G.
10.1101/2022.04.08.486845 — biochemistry — Posted on 2022-11-28
325 Distinct Differences in Gene Expression Profiles in Early and Late Stage Rhodesiense HAT Individuals in Malawi
Nambala, P.; Mulindwa, J.; Noyes, H.; Namulondo, J.; Nyangiri, O.; Matovu, E.; MacLeod, A.; Musaya, J.
10.1101/2022.11.28.518140 — genetics — Posted on 2022-11-28
329 Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination
Adams, L. E.; Leist, S. R.; Dinnon, K. H.; West, A.; Gully, K. L.; Anderson, E.; Loome, J. F.; Madden, E.; Powers, J.; Schaefer, A.; Sarkar, S.; Castillo, I.; Maron, J.; McNamara, R. P.; Bertera, H. L.; Zweigart, M. R.; Higgins, J. S.; Hampton, B. K.; Lakshmanane, P.; Alter, G.; Montgomery, S.; Baxter, V.; Heise, M. T.; Baric, R. S.
10.1101/2022.11.28.518175 — microbiology — Posted on 2022-11-28
330 Population genomics, resistance, pathogenic potential, and mobile genetic elements of carbapenem-resistant Klebsiella pneumoniae causing infections in Chile
Veloso, M.; Acosta, J.; Arros, P.; Berrios-Pasten, C.; Rojas, R.; Varas, M.; Allende, M. L.; Chavez, F. P.; Araya, P.; Hormazabal, J. C.; Lagos, R.; Marcoleta, A. E.
10.1101/2022.11.28.517876 — microbiology — Posted on 2022-11-28
332 The simulation of functional heterogeneity in procedurally generated fibrotic atrial tissue
Kalinin, A.; Kovalenko, S.; Berezhnoy, A. K.; Slotvitsky, M. M.; Shcherbina, S.; Syrovnev, V.; Tsvelaya, V. A.
10.1101/2022.11.28.518223 — biophysics — Posted on 2022-11-28
333 Zebrafish screen of high-confidence effector genes at insomnia GWAS loci implicates conserved regulators of sleep-wake behaviors
Zimmerman, A. J.; Doldur-Balli, F.; Keenan, B. T.; Shetty, Z. Y.; Palermo, J.; Chesi, A.; Sonti, S.; Pahl, M. C.; Brown, E. B.; Pippin, J. A.; Wells, A. D.; Mazzotti, D. R.; Veatch, O. J.; Krishnan, A.; Gehrman, P. R.; Keene, A. C.; Grant, S. F. A.; Pack, A. I.
10.1101/2022.10.05.511011 — genetics — Posted on 2022-11-28
334 Loss of Bcl6 transcriptionally alters classical dendritic cells and diminishes T follicular helper cell and Th17-inducing cDC2 in mice
Xiao, H.; Ulmert, I.; Huber, J.; Narasimhan, H.; Bach, L.; Kurochkin, I.; Moerbe, U.; Zhang, L.; Schlitzer, A.; Pereira, F.; Schraml, B.; Baumjohann, D.; Lahl, K.
10.1101/2022.08.10.503322 — immunology — Posted on 2022-11-28
335 LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics
Ruffini, G.; Damiani, G.; Lozano-Soldevilla, D.; Deco, N.; Rosas, F.; Kiani, N.; Ponce-Alvarez, A.; Kringelbach, M. L.; Carhart-Harris, R.; Deco, G. L.
10.1101/2022.08.27.505518 — neuroscience — Posted on 2022-11-28
339 Systematic Discovery of Antibacterial and Antifungal Bacterial Toxins
Nachmias, N.; Dotan, N.; Fraenkel, R.; Rocha, M. C.; Kluzek, M.; Shalom, M.; Rivitz, A.; Shamash-Halevy, N.; Cahana, I.; Deouell, N.; Klein, J.; Schlezinger, N.; Tzarum, N.; Oppenheimer-Shaanan, Y.; Levy, A.
10.1101/2021.10.19.465003 — microbiology — Posted on 2022-11-28
343 Extracellular disintegration of viral proteins as an innovative strategy for developing broad-spectrum antivirals against coronavirus
Sun, K.; Ding, Z.; Jia, X.; Cheng, H.; Li, Y.; Wu, Y.; Li, Z.; Huang, X.; Pu, F.; Li, E.; Wang, G.; Wang, W.; Ding, Y.; Wong, G.; Chiu, S.; Lan, J.; Hu, A.
10.1101/2022.11.24.517008 — biochemistry — Posted on 2022-11-28
346 Highly potent antisense oligonucleotides (ASOs) targeting the SARS-CoV-2 RNA genome
Dauksaite, V.; Tas, A.; Wachowius, F.; Spruit, A.; van Hemert, M.; Snijder, E.; van der Veer, E. P.; van Zonneveld, A. J.
10.1101/2022.11.28.518195 — molecular biology — Posted on 2022-11-28
347 Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants
Wang, Q.; Iketani, S.; Li, Z.; Liu, L.; Guo, Y.; Huang, Y.; Bowen, A. D.; Liu, M.; Wang, M.; Yu, J.; Valdez, R.; Lauring, A. S.; Sheng, Z.; Wang, H. H.; Gordon, A.; Liu, L.; Ho, D. D.
10.1101/2022.11.23.517532 — microbiology — Posted on 2022-11-28
349 Long-term immune protection against SARS-CoV-2 escape variants upon a single vaccination with murine cytomegalovirus expressing the spike protein
Kim, Y.; Jackobsen, H.; Fuerholzner, B.; Eschke, K.; Hoffmann, M.; Chaudhry, M. Z.; Bertoglio, F.; Hust, M.; Widera, M.; Ciesek, S.; Poehlmann, S.; Cicin-Sain, L.
10.1101/2022.11.25.517953 — immunology — Posted on 2022-11-28
350 Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2
Bianchini, F.; Crivelli, V.; Abernathy, M. E.; Guerra, C.; Palus, M.; Muri, J.; Marcotte, H.; Piralla, A.; Pedotti, M.; De, R.; Simonelli, L.; Matkovic, M.; Toscano, C.; Biggiogero, M.; Calvaruso, V.; Svoboda, P.; Cervantes Rincon, T.; Fava, T.; Podesvova, L.; Shanbhag, A. A.; Celoria, A.; Sgrignani, J.; Stefanik, M.; Hoenig, V.; Pranclova, V.; Michalcikova, T.; Prochazka, J.; Guerrini, G.; Mehn, D.; Ciabattini, A.; Abolhassani, H.; Jarrossay, D.; Uguccioni, M.; Medaglini, D.; Pan-Hammarstroem, Q.; Calzolai, L.; Fernandez, D.; Baldanti, F.; Franzetti-Pellanda, A.; Garzoni, C.; Sedlacek, R.; Ru
10.1101/2022.11.24.515932 — immunology — Posted on 2022-11-28
354 Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma
Panovska, D.; Nazari, P.; Cole, B.; Creemers, P.-J.; Derweduwe, M.; Solie, L.; Van Gassen, S.; Claeys, A.; Verbeke, T.; Saeys, Y.; Van Der Planken, D.; Bosisio, F. M.; Put, E.; Bamps, S.; Clement, P.; Verfaillie, M.; Sciot, R.; Ligon, K. L.; De Vleeschouwer, S.; Martinez, A.; De Smet, F.
10.1101/2022.10.17.512525 — cancer biology — Posted on 2022-11-28
360 PhosphoLingo: protein language models for phosphorylation site prediction
Zuallaert, J.; Ramasamy, P.; Bouwmeester, R.; Callewaert, N.; Degroeve, S.
10.1101/2022.11.28.518163 — bioinformatics — Posted on 2022-11-28
363 Antimicrobial resistance gene lack in tick-borne pathogenic bacteria
Papp, M.; Toth, A. G.; Valcz, G.; Makrai, L.; Nagy, S. A.; Farkas, R.; Solymosi, N.
10.1101/2022.11.28.518145 — genomics — Posted on 2022-11-28
364 Generate a new crucian carp (Carassius auratus) strain without intermuscular bones by knocking out bmp6
Kuang, Y.; Zheng, X.; Cao, D.; Sun, Z.; Tong, G.; Xu, H.; Yan, T.; Tang, S.; Chen, Z.; Zhang, T.; Zhang, T.; Dong, L.; Yang, X.; Zhou, H.; Guo, W.; Sun, X.
10.1101/2022.11.28.518130 — genetics — Posted on 2022-11-28
367 Genomic consequences of range expansion and colonisation in the reed warbler (Acrocephalus scirpaceus)
Saetre, C. L. C.; Rönkä, K.; Ravinet, M.; Vitulano, S.; Caldarella, M.; Prochazka, P.; Stokke, B.; Cuevas, A.; Bergman, N.; Thorogood, R.; Jakobsen, K. S.; Torresen, O. K.; Eroukhmanoff, F.
10.1101/2022.11.28.518135 — evolutionary biology — Posted on 2022-11-28
368 Evolution along allometric lines of least resistance: Morphological differentiation in Pristurus geckos
Tejero-Cicuendez, H.; Menendez, I.; Talavera, A.; Riano, G.; Burriel-Carranza, B.; Simo-Riudalbas, M.; Carranza, S.; Adams, D. C.
10.1101/2022.11.28.518148 — evolutionary biology — Posted on 2022-11-28
372 Reconceptualizing beta diversity: a hypervolume geometric approach
Song, C.; Lu, M.; Bennett, J. R.; Gilbert, B.; Fortin, M.-J.; Gonzalez, A.
10.1101/2022.11.27.518099 — ecology — Posted on 2022-11-28
377 Noncannonical functions of Ku may underlie essentiality in human cells
Kelly, R. D.; Parmar, G.; Bayat, L.; Maitland, M. E. R.; Lajoie, G. A.; Edgell, D. R.; Schild-Poulter, C.
10.1101/2022.11.28.518141 — molecular biology — Posted on 2022-11-28
378 Proteomic Analysis Defines the Interactome of Telomerase in the Protozoan Parasite, Trypanosoma brucei
Davis, J. A.; Reyes, A. V.; Nitika, ; Saha, A.; Wolfgeher, D. J.; Xu, S.-L.; Truman, A.; Li, B.; Chakrabarti, K.
10.1101/2022.11.27.518122 — molecular biology — Posted on 2022-11-28
379 Ultrastructural characterization of a viral RNA and G-protein containing, membranous organelle formed in respiratory syncytial virus infected cells
Vijayakrishnan, S.; Burns, A. M.; Blanchard, E. L.; Spink, M. C.; Gilchrist, J.; Howe, A.; Darrow, M. C.; Harkiolaki, M.; Wu, C.-Y.; Dutch, R. E.; Santangelo, P.; Fearns, R.; Bhella, D.
10.1101/2022.11.28.517999 — microbiology — Posted on 2022-11-28
382 Cross-species analysis identifies conserved transcriptional mechanisms of neutrophil maturation
Kirchberger, S.; Shoeb, M. R.; Lazic, D.; Fischer, K.; Shaw, L. E.; Nogueira, F.; Rifatbegovic, F.; Bozsaky, E.; Ladenstein, R.; Bodenmiller, B.; Lion, T.; Traver, D.; Farlik, M.; Taschner-Mandl, S.; Halbritter, F.; Distel, M.
10.1101/2022.11.28.518146 — immunology — Posted on 2022-11-28
385 Balance between direct and indirect pathways of the nucleus accumbens controls social behavior in mice
Le Merrer, J.; Detraux, B.; Gandia, J.; De Groote, A.; Fonteneau, M.; de Kerchove d'Exaerde, A.; Becker, J. A. J.
10.1101/2022.11.28.518147 — neuroscience — Posted on 2022-11-28
386 Astrocyte MCT1 expression does not contribute to the axonal degenerative phenotype observed with ubiquitous MCT1 depletion.
Phillips, T.; Thompson, E. G.; Vijayakumar, B. G.; Kent, E. R.; Millar, S. J.; Vidensky, S.; Farah, M. H.; Rothstein, J. D.
10.1101/2022.11.27.518094 — neuroscience — Posted on 2022-11-28
387 Global Endometrial DNA Multi-omics Analysis Reveals Insights into mQTL Regulation and Associated Endometriosis Disease Risk
Mortlock, S.; Houshdaran, S.; Kosti, I.; Rahmioglu, N.; Nezhat, C.; Vitonis, A. F.; Andrews, S. V.; Grosjean, P.; Paranjpe, M.; Horne, A. W.; Jacoby, A.; Lager, J.; Opoku-Anane, J.; Vo, K. C.; Manvelyan, E.; Sen, S.; Ghukasyan, Z.; Collins, F.; Santamaria, X.; Saunders, P.; Kober, K.; McRae, A. F.; Terry, K. L.; Vallve-Juanico, J.; Becker, C.; Rogers, P. A. W.; Irwin, J. C.; Zondervan, K.; Montgomery, G. W.; Missmer, S.; Sirota, M.; Giudice, L.
10.1101/2022.11.27.518106 — systems biology — Posted on 2022-11-28
389 ABLs and TMKs are co-receptors for extracellular auxin
Yu, Y.; Tang, W.; Lin, W.; Li, W.; Zhou, X.; Li, Y.; Chen, R.; Zheng, R.; Qin, G.; Cao, W.; Perez, P.; Huang, R.; Ma, J.; Lin, J.; Jiang, L.; Xu, T.; Yang, Z.
10.1101/2022.11.28.518138 — plant biology — Posted on 2022-11-28
391 Inferring Spatially Resolved Transcriptomics Data from Whole Slide Images for the Assessment of Colorectal Tumor Metastasis: A Feasibility Study
Fatemi, M.; Feng, E.; Sharma, C.; Azher, Z.; Goel, T.; Ramwala, O.; Palisoul, S.; Barney, R.; Perreard, L.; Kolling, F.; Salas, L. A.; Christensen, B.; Tsongalis, G.; Vaickus, L.; Levy, J.
10.1101/2022.11.24.517856 — pathology — Posted on 2022-11-28
395 Evidence that SPIO Chain Formation is Essential for High-Resolution MPI
Colson, C.; Fung, K. L. B.; Bryan, J.; Tay, Z. W.; Fellows, B. D.; Sayuujya, C.; Kuo, R.; Chandrasekharan, P.; Conolly, S. M.
10.1101/2022.11.27.518061 — bioengineering — Posted on 2022-11-28
397 Hypoxic tumors are sensitive to FLASH radiotherapy
Leavitt, R. J.; Almeida, A.; Grilj, V.; Montay-Gruel, P.; Godfroid, C.; Petit, B.; Bailat, C.; Limoli, C. L.; Vozenin, M.-C.
10.1101/2022.11.27.518083 — cancer biology — Posted on 2022-11-28
400 β-Lapachone Regulates Mammalian Inositol Pyrophosphate Levels in an NQO1- and Oxygen-dependent Manner
Eisenbeis, V. B.; Qiu, D.; Strotmann, L.; Liu, G.; Prucker, I.; Ritter, K.; Loenarz, C.; Saiardi, A.; Jessen, H. J.
10.1101/2022.11.27.518098 — biochemistry — Posted on 2022-11-28
402 The connectome of an insect brain
Winding, M.; Pedigo, B. D.; Barnes, C. L.; Patsolic, H. G.; Park, Y.; Kazimiers, T.; Fushiki, A.; Andrade, I. V.; Li, F.; Valdes-Aleman, J.; Khandelwal, A.; Randel, N.; Barsotti, E.; Correia, A.; Fetter, R. D.; Hartenstein, V.; Priebe, C. E.; Vogelstein, J. T.; Cardona, A.; Zlatic, M.
10.1101/2022.11.28.516756 — neuroscience — Posted on 2022-11-28
403 PTPN1 deficiency modulates BMPR2 signaling and induces endothelial dysfunction in Pulmonary Arterial Hypertension
Ali, M. K.; Tian, X.; Zhao, L.; Schimmel, K.; Rhodes, C. J.; Wilkins, M.; Nicolls, M. R.; Spiekerkoetter, E.
10.1101/2022.11.27.518092 — cell biology — Posted on 2022-11-28
404 DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon
Wolfson, R. L.; Abdelaziz, A.; Rankin, G.; Kushner, S.; Qi, L.; Mazor, O.; Choi, S.; Sharma, N.; Ginty, D. D.
10.1101/2022.11.27.518103 — neuroscience — Posted on 2022-11-28
405 New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy
Yang, Y.; Garringer, H. J.; Shi, Y.; Lövestam, S.; Zhang, X.; Kotecha, A.; Bacioglu, M.; Koto, A.; Takao, M.; Spillantini, M. G.; Ghetti, B.; Vidal, R.; Murzin, A. G.; Scheres, S. H.; Goedert, M.
10.1101/2022.11.23.517690 — neuroscience — Posted on 2022-11-28
406 Multifaceted quality assessment of gene repertoire annotation with OMArk
Nevers, Y.; Rossier, V.; Train, C.; Altenhoff, A. M.; Dessimoz, C.; Glover, N.
10.1101/2022.11.25.517970 — bioinformatics — Posted on 2022-11-28
407 A lysosomal lipid transport pathway that enables cell survival under cholinelimitation
Scharenberg, S. G.; Dong, W.; Nyame, K.; Levin-Konigsberg, R.; Krishnan, A. R.; Rawat, E. S.; Spees, K.; Bassik, M. C.; Abu-Remaileh, M.
10.1101/2022.11.27.517422 — cell biology — Posted on 2022-11-28
408 Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
Kahraman, S.; Shibue, K.; De Jesus, D. F.; Hu, J.; Manna, D.; Wagner, B.; Choudhary, A.; Kulkarni, R. N.
10.1101/2022.11.27.518097 — cell biology — Posted on 2022-11-28
413 Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-TSCM cells using qCART, the Quantum pBac-based CAR-T system
Chang, P. S.; Chen, Y.-C.; Hua, W.-K.; Hsu, J. C.; Tsai, J.-C.; Huang, Y.-W.; Kao, Y.-H.; Wu, P.-H.; Chang, Y.-F.; Chang, M. C.; Chang, Y. C.; Jian, S.-L.; Lai, J.-S.; Lai, M.-T.; Yang, W.-C.; Shen, C.-N.; Wen, K.-L. K.; Wu, S. C.-Y.
10.1101/2022.05.03.490475 — cancer biology — Posted on 2022-11-28
414 Quantum CART (qCART), a piggyBac-based system for development and production of virus-free multiplex CAR-T cell therapy
Chen, Y.-C.; Hua, W.-K.; Hsu, J. C.; Chang, P. S.; Wen, K.-L. K.; Huang, Y.-W.; Tsai, J.-C.; Kao, Y.-H.; Wu, P.-H.; Wang, P.-N.; Chen, K.-F.; Liao, W.-T.; Wu, S. C.-Y.
10.1101/2022.05.03.490469 — cancer biology — Posted on 2022-11-28
415 PIEZO2 in somatosensory neurons controls gastrointestinal transit
Servin-Vences, M. R.; Lam, R. M.; Koolen, A.; Wang, Y.; Saade, D. N.; Loud, M.; Kacmaz, H.; Beyder, A.; Marshall, K. L.; Bonnemann, C.; Chesler, A. T.; Patapoutian, A.
10.1101/2022.11.27.518109 — neuroscience — Posted on 2022-11-28
417 Quantum pBac: An effective, high-capacity piggyBac-based gene integration vector system for unlocking gene therapy potential
Hua, W.-K.; Hsu, J. C.; Chen, Y.-C.; Chang, P. S.; Wen, K.-L. K.; Wang, P.-N.; Yu, Y.-S.; Chen, Y.-C.; Cheng, I.-C.; Wu, S. C.-Y.
10.1101/2022.04.29.490002 — cancer biology — Posted on 2022-11-28
419 Expected Costs of Mental Efforts are Updated When People Exert Effort, not by Prospective Information
Nagase, A. M.; Westbrook, A.; Onoda, K.; Morita, K.; Kawagoe, T.; Yamaguchi, S.; Akaishi, R.; Hanajima, R.
10.1101/2022.11.26.518013 — neuroscience — Posted on 2022-11-27
423 NR5A2 connects genome activation to the first lineage segregation in early mouse development
Lai, F.; Li, L.; Hu, X.; Liu, B.; Zhu, Z.; Liu, L.; Tian, H.; Xu, K.; Lu, X.; Li, Q.; Kong, F.; Wang, L.; Lin, Z.; Deng, H.; Li, J.; Xie, W.
10.1101/2022.11.25.518012 — developmental biology — Posted on 2022-11-27
424 Coordinated multiplexing of information about separate objects in visual cortex
Jun, N. Y.; Ruff, D. A.; Kramer, L. E.; Bowes, B.; Tokdar, S. T.; Cohen, M. R.; Groh, J. M.
10.1101/777912 — neuroscience — Posted on 2022-11-27
427 Prediction of Stroke Outcome in Mice Based on Non-Invasive MRI and Behavioral Testing
Knab, F.; Koch, S. P.; Major, S.; Farr, T. D.; Mueller, S.; Euskirchen, P.; Eggers, M.; Kuffner, M. T. C.; Walter, J.; Dreier, J. P.; Endres, M.; Dirnagl, U.; Wenger, N.; Hoffmann, C.; Boehm-Sturm, P.; Harms, C.
10.1101/2022.05.13.491869 — neuroscience — Posted on 2022-11-27
428 Fronto-parietal networks shape human conscious report through attention gain and reorienting
Liu, J.; Bayle, D. J.; Spagna, A.; Sitt, J. D.; Bourgeois, A.; Lehongre, K.; Fernandez-Vidal, S.; Adam, C.; Lambrecq, V.; Navarro, V.; Malkinson, T. S.; Bartolomeo, P.
10.1101/2022.04.10.487690 — neuroscience — Posted on 2022-11-27
429 A Multi-Parametric and High-Throughput Platform for Host-Virus Binding Screens
Schlegel, J.; Porebski, B.; Andronico, L.; Hanke, L.; Edwards, S.; Brismar, H.; Murrell, B.; McInerney, G. M.; Fernandez-Capetillo, O.; Sezgin, E.
10.1101/2022.10.10.511545 — synthetic biology — Posted on 2022-11-27
431 Microenvironmental Snail1 is a driver of immunosuppression in melanoma
Arumi-Planas, M.; Rodriguez-Baena, F. J.; Cabello-Torres, F.; Gracia, F.; Lopez-Blau, C.; Nieto, A.; Sanchez-Laorden, B.
10.1101/2022.11.23.517623 — cancer biology — Posted on 2022-11-27
434 Magnetic Bead Based Proximity Extension Assay for Sensitive Protein and Extracellular Vesicles Detection
Muthelo, P. M.; Ebai, T.; Doulabi, E. M.; Al-Amin, R. A.; Wu, Y.; Kamali-Moghaddam, M.; Landegren, U.
10.1101/2022.11.27.518072 — biochemistry — Posted on 2022-11-27
438 Parametric information about eye movements is sent to the ears
Lovich, S. N.; King, C. D.; Murphy, D. L. K.; Landrum, R.; Shera, C. A.; Groh, J. M.
10.1101/2022.11.27.518089 — neuroscience — Posted on 2022-11-27
440 Inferring delays in partially observed gene regulatory networks
Hong, H.; Cortez, M. J.; Cheng, Y.-Y.; Kim, H. J.; Choi, B.; Josic, K.; Kim, J. K.
10.1101/2022.11.27.518074 — bioinformatics — Posted on 2022-11-27
442 Fungal antibiotics control bacterial community diversity in the cheese rind microbiome
Tannous, J.; Cosetta, C.; Drott, M. T.; Rush, T. A.; Abraham, P. E.; Giannone, R. J.; Keller, N. P.; Wolfe, B. E.
10.1101/2022.11.26.518062 — microbiology — Posted on 2022-11-27
446 Two differentiated brain systems micro-structurally associated with obesity
Kitzbichler, M. G.; Martins, D. G.; Bethlehem, R. A. I.; Dear, R.; Romero-Garcia, R.; Warrier, V.; Seidlitz, J.; Dipasquale, O.; Turkheimer, F. E.; Cercignani, M.; Bullmore, E. T.; Harrison, N. A.
10.1101/2022.11.25.517981 — neuroscience — Posted on 2022-11-27
448 Expected Costs of Mental Efforts are Updated When People Exert Effort, not by Prospective Information
Nagase, A. M.; Westbrook, A.; Onoda, K.; Morita, K.; Kawagoe, T.; Yamaguchi, S.; Akaishi, R.; Hanajima, R.
10.1101/2022.11.26.518013 — neuroscience — Posted on 2022-11-27
450 SLIDE: Significant Latent Factor Interaction Discovery and Exploration across biological domains
Rahimikollu, J.; Xiao, H.; Rosengart, A. E.; Tabib, T.; Zdinak, P. M.; He, K.; Bing, X.; Bunea, F.; Wegkamp, M.; Poholek, A. C.; Joglekar, A. V.; Lafyatis, R. A.; Das, J.
10.1101/2022.11.25.518001 — systems biology — Posted on 2022-11-27
454 Instantly adhesive and ultra-elastic patches for dynamic organ and wound repair
Chansoria, P.; Bonacquisti, E. E.; Heavey, M. M.; Le, L.; Maruthamuthu, M. K.; Blackwell, J.; Jasiewicz, N.; Sellers, R.; Maile, R.; Wallet, S. M.; Egan, T.; Nguyen, J.
10.1101/2022.11.25.517820 — bioengineering — Posted on 2022-11-27
456 Calculating functional diversity metrics using neighbor-joining trees
Cardoso, P.; Guillerme, T.; Mammola, S.; Matthews, T.; Rigal, F.; Graco-Roza, C.; Stahls, G.; Carvalho, J. C.
10.1101/2022.11.27.518065 — ecology — Posted on 2022-11-27
457 Anti-chemokine antibodies after SARS-CoV-2 infection correlate with favorable disease course
Muri, J.; Cecchinato, V.; Cavalli, A.; Shanbhag, A. A.; Matkovic, M.; Biggiogero, M.; Maida, P. A.; Moritz, J.; Toscano, C.; Ghovehoud, E.; Furlan, R.; Barbic, F.; Voza, A.; De Nadai, G.; Cervia, C.; Zurbuchen, Y.; Taeschler, P.; Murray, L. A.; Danelon-Sargenti, G.; Moro, S.; Gong, T.; Piffaretti, P.; Bianchini, F.; Crivelli, V.; Podesvova, L.; Pedotti, M.; Jarrossay, D.; Sgrignani, J.; Thelen, S.; Uhr, M.; Bernasconi, E.; Rauch, A.; Manzo, A.; Ciurea, A.; Rocchi, M. B. L.; Varani, L.; Moser, B.; Bottazzi, B.; Thelen, M.; Fallon, B. A.; Boyman, O.; Mantovani, A.; Garzoni, C.; Franzetti-Pelland
10.1101/2022.05.23.493121 — immunology — Posted on 2022-11-27
458 Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands
Fierro, F.; Peri, L.; Huebner, H.; Tabor-Schkade, A.; Waterloo, L.; Loeber, S.; Pfeiffer, T.; Dingjan, T.; Margulis, E.; Gmeiner, P.; Niv, M. Y.
10.1101/2022.11.24.517821 — bioinformatics — Posted on 2022-11-27
459 Divergent and dominant anti-inflammatory effects of patient-derived anti-citrullinated protein antibodies (ACPA) in arthritis development
Raposo, B.; Afonso, M. G.; Israelsson, L.; Wähämaa, H.; Stalesen, R.; Wermeling, F.; Hensvold, A.; Grönwall, C.; Rethi, B.; Klareskog, L.; Malmström, V.
10.1101/2022.09.30.510377 — immunology — Posted on 2022-11-27
462 The cytochrome b carboxyl-terminal region is necessary for mitochondrial Complex III assembly
Flores-Mireles, D.; Camacho-Villasana, Y.; Lutikurti, M.; Garcia-Guerrero, A. E.; Lozano-Rosas, G.; Chagoya, V.; Gutierrez-Cirlos, E. B.; Brandt, U.; Cabrera-Orefice, A.; Perez-Martinez, X.
10.1101/2022.11.25.517933 — biochemistry — Posted on 2022-11-27
466 Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy
Cunha, P. P.; Minogue, E.; Krause, L. C.; Hess, R. M.; Bargiela, D.; Wadsworth, B. J.; Barbieri, L.; Brombach, C.; Foskolou, I. P.; Bogeski, I.; Velica, P.; Johnson, R.
10.1101/2022.11.25.517976 — immunology — Posted on 2022-11-27
468 microRNA165 and 166 modulate salt stress response of the Arabidopsis root.
Scintu, D.; Scacchi, E.; Cazzaniga, F.; Vinciarelli, F.; De Vivo, M.; Shtin, M.; Svolacchia, N.; Bertolotti, G.; Unterholzner, S. J.; Del Bianco, M.; Timmermans, M.; Di Mambro, R.; Sabatini, S.; Costantino, P.; Dello Ioio, R.
10.1101/2022.11.25.517945 — plant biology — Posted on 2022-11-27
471 SlideCNA: Spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data
Zhang, D. K.; Segerstolpe, A.; Slyper, M.; Waldman, J.; Murray, E.; Cohen, O.; Ashenberg, O.; Abravanel, D.; Jane-Valbuena, J.; Mages, S.; Lako, A.; Helvie, K.; Rozenblatt-Rosen, O.; Rodig, S.; Chen, F.; Wagle, N.; Regev, A.; Klughammer, J.
10.1101/2022.11.25.517982 — bioinformatics — Posted on 2022-11-27
472 Genetic variation in mouse islet Ca2+ oscillations reveals novel regulators of islet function
Emfinger, C.; Clark, L. E.; Schueler, K. L.; Simonett, S.; Stapleton, D. S.; Mitok, K.; Merrins, M. J.; Keller, M. P.; Attie, A. D.
10.1101/2022.11.26.517741 — biochemistry — Posted on 2022-11-27
473 The dynamic nature of neurotensin receptor 1 (NTS1) allostery and signaling bias
Bumbak, F.; Inoue, A.; Pons, M.; Paniagua, J. C.; Yan, F.; Wu, H.; ROBSON, S. A.; Bathgate, R. A. D.; Scott, D. J.; Gooley, P. R.; Ziarek, J. J.
10.1101/2022.11.25.517797 — biochemistry — Posted on 2022-11-27
474 Contrasting genomic consequences of anthropogenic reintroduction and natural recolonisation in high-arctic wild reindeer
Burnett, H. A.; Bieker, V. C.; Le Moullec, M.; Peeters, B.; Rosvold, J.; Pedersen, A. O.; Dalen, L.; Loe, L. E.; Jensen, H.; Hansen, B. B.; Martin, M. D.
10.1101/2022.11.25.517957 — genomics — Posted on 2022-11-27
478 The virome of the invasive Asian bush mosquito Aedes japonicus in Europe
Abbo, S. R.; de Almeida, J. P. P.; Olmo, R. P.; Balvers, C.; Griep, J. S.; Linthout, C.; Koenraadt, C. J. M.; Silva, B. M.; Fros, J. J.; Aguiar, E. R. G. R.; Marois, E.; Pijlman, G. P.; Marques, J. T.
10.1101/2022.11.26.518030 — microbiology — Posted on 2022-11-26
479 Quantitative analyses of T cell motion in tissue reveals factors driving T cell search in tissues
Torres, D. J.; Mrass, P.; Byrum, J.; Gonzales, A.; Martinez, D.; Juarez, M. E.; Thompson, E.; Vezys, V.; Cannon, J. L.
10.1101/2022.11.17.516891 — immunology — Posted on 2022-11-27
480 Quantitative assessment of angioplasty induced vascular inflammation with 19F cardiovascular magnetic resonance imaging
Nienhaus, F.; Walz, M.; Rothe, M.; Jahn, A.; Pfeiler, S.; Busch, H. L.; Stern, M.; Heiss, C.; Vornholz, L.; Cames, S.; Cramer, M.; Schrauwen-Hinderling, V.; Gerdes, N.; Temme, S.; Roden, M.; Floegel, U.; Kelm, M.; Boenner, F.
10.1101/2022.11.25.518014 — immunology — Posted on 2022-11-27
481 Cell type-specific attenuation of brassinosteroid signalling drives stomatal asymmetric cell division
Kim, E.-J.; Zhang, C.; Guo, B.; Eekhout, T.; Houbaert, A.; Wendrich, J. R.; Vandamme, N.; Tiwari, M.; Simon--Vezo, C.; Vanhoutte, I.; Saeys, Y.; Wang, K.; Zhu, Y.; De Rybel, B.; Russinova, E.
10.1101/2022.11.26.518021 — plant biology — Posted on 2022-11-27
483 Centromere-associated retroelement evolution in Drosophila melanogaster reveals an underlying conflict
Hemmer, L. W.; Negm, S.; Geng, X.; Courret, C.; Navarro-Dominguez, B.; Speece, I.; Wei, X.; Altidor, E.; Chaffer, J.; Sproul, J. S.; Larracuente, A. M.
10.1101/2022.11.25.518008 — genomics — Posted on 2022-11-26
489 Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of Legionella pneumophila
Lin, J. D.; Stogios, P. J.; Abe, K. T.; Wang, A.; MacPherson, J.; Skarina, T.; Gingras, A.-C.; Savchenko, A.; Ensminger, A. W.
10.1101/2022.11.26.518041 — microbiology — Posted on 2022-11-26
497 Unique functions of two overlapping PAX6 retinal enhancers
Uttley, K.; Papanastasiou, A. S.; Lahne, M.; Brisbane, J. M.; MacDonald, R. B.; Bickmore, W. A.; Bhatia, s.
10.1101/2022.11.25.517987 — genetics — Posted on 2022-11-26
499 A primary microcephaly-associated sas-6 mutation perturbs centrosome duplication and ciliogenesis in Caenorhabditis elegans
Bergwell, M.; Smith, A.; Smith, E.; Duran, R.; Haastrup, E.; Napier-Jameson, R.; Dierlam, C.; Seidel, R.; Potter, W.; Norris, A.; Iyer, J.
10.1101/2022.11.25.518003 — genetics — Posted on 2022-11-26
500 Variation in anthelmintic responses are driven by genetic differences among diverse C. elegans strains
Shaver, A. O.; Wit, J.; Dilks, C. M.; Crombie, T. A.; Li, H.; Aroian, R. V.; Andersen, E. C.
10.1101/2022.11.26.518036 — genetics — Posted on 2022-11-26
502 The endocytic recycling pathway is controlled by the ADP-ribosylated GTPase Rab14
Corteggio, A.; Lo Monte, M.; Schembri, L.; Dathan, N.; Di Paola, S.; Grimaldi, G.; Corda, D.
10.1101/2022.11.26.517555 — cell biology — Posted on 2022-11-26
504 Structural and dynamical basis for the interaction of HSP70-EEVD with JDP Sis1
Matos, C. O.; Pinheiro, G. M. S.; Caruso, I. P.; Amorim, G. C.; Almeida, F. C. L.; Ramos, C. H. I.
10.1101/2022.11.26.517237 — molecular biology — Posted on 2022-11-26
508 Resilient CD8+ T cells maintain a high cytotoxic capacity by balancing ROS via ME1 upregulation
Gicobi, J. K.; Mao, Z.; DeFranco, G.; Li, Y.; Liu, C.; Hirdler, J. B.; Vianzon, V. V.; Dellacecca, E. R.; Hsu, M. A.; Barham, W.; Kim, Y. H.; Feven, A.; Harmsen, W. S.; Yan, Y.; Dronca, R. S.; Zhu, M.; Markovic, S.; Mansfield, A. S.; Lin, Y.; Wu, X.; Owen, D.; Grams, M. P.; Orme, J. J.; Lucien, F.; Zeng, H.; Park, S. S.; Dong, H.
10.1101/2022.11.25.517988 — immunology — Posted on 2022-11-26
510 Developing best practices for genotyping-by-sequencing analysis using linkage maps as benchmarks
Taniguti, C. H.; Taniguti, L. M.; Amadeu, R. R.; Lau, J.; Gesteira, G. d. S.; Oliveira, T. d. P.; Ferreira, G. C.; Pereira, G. d. S.; Byrne, D.; Mollinari, M.; Riera-Lizarazu, O.; Garcia, A. A. F.
10.1101/2022.11.24.517847 — bioinformatics — Posted on 2022-11-26
512 Proteomic Landscape of Human Spermatozoa: Optimized Extraction Method and Application
Luo, M.; Su, T.; Wang, S.; Chen, J.; Cheng, Q.; Lin, T.; Chen, Y.; Gong, M.; Yang, H.; Li, F.; Zhang, Y.
10.1101/2022.11.25.518017 — biochemistry — Posted on 2022-11-26
514 Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2
Tsyklauri, O.; Chadimova, T.; Niederlova, V.; Kovarova, J.; Michalik, J.; Malatova, I.; Janusova, S.; Ivashchenko, O.; Rossez, H.; Drobek, A.; Vecerova, H.; Galati, V.; Kovar, M.; Stepanek, O.
10.1101/2021.11.10.467495 — immunology — Posted on 2022-11-26
515 Spatio-Temporal Dynamics of Oscillatory Brain Activity during the Observation of Actions and Interactions between Point-light Agents
Friedrich, E. V. C.; Zillekens, I.; Biel, A. L.; O'Leary, D.; Singer, J.; Seegenschmiedt, E. V.; Sauseng, P.; Schilbach, L.
10.1101/2022.08.16.504090 — neuroscience — Posted on 2022-11-26
519 NR5A2 connects genome activation to the first lineage segregation in early mouse development
Lai, F.; Li, L.; Hu, X.; Liu, B.; Zhu, Z.; Liu, L.; Tian, H.; Xu, K.; Lu, X.; Li, Q.; Kong, F.; Wang, L.; Lin, Z.; Deng, H.; Li, J.; Xie, W.
10.1101/2022.11.25.518012 — developmental biology — Posted on 2022-11-26
520 Extracellular matrix protein anosmin-1 overexpression regulates dopaminergic phenotype in the CNS and the PNS with no pathogenic consequences in MPTP model of Parkinson disease
Villadiego, J.; Garcia-Swinburn, R.; Garcia-Gonzalez, D.; Lebron-Galan, R.; Murcia-Belmonte, V.; Garcia-Roldan, E.; Suarez-Luna, N.; Nombela, C.; Marchena, M.; de Castro, F.; Toledo-Aral, J. J.
10.1101/2022.11.25.517917 — neuroscience — Posted on 2022-11-26
522 Kinetic models for PET displacement studies
Laurell, G. L.; Plaven-Sigray, P.; Johansen, A.; Raval, N. R.; Nasser, A.; Madsen, C. A.; Madsen, J.; Hansen, H. D.; Donovan, L. L.; Knudsen, G. M.; Lammertsma, A. A.; Ogden, R. T.; Svarer, C.; Schain, M.
10.1101/2022.11.25.517914 — neuroscience — Posted on 2022-11-26
527 Self-Regulation of Visual Word Form Area activation with real-time fMRI neurofeedback
Haugg, A.; Frei, N.; Menghini, M.; Stutz, F.; Steinegger, S.; Roethlisberger, M.; Brem, S.
10.1101/2022.11.25.517926 — neuroscience — Posted on 2022-11-26
530 Dendritic modulation enables multitask representation learning in hierarchical sensory processing pathways
Wybo, W. A. M.; Tsai, M. C.; Tran, V. A. K.; Illing, B.; Jordan, J.; Morrison, A.; Senn, W.
10.1101/2022.11.25.517941 — neuroscience — Posted on 2022-11-26
532 Mimicking genuine drought responses using a high throughput plate assay
Gonzalez, S.; Swift, J.; Xu, J.; Illouz-Eliaz, N.; Nery, J. R.; Ecker, J. R.
10.1101/2022.11.25.517922 — plant biology — Posted on 2022-11-26
533 Self-Supervised Maize Kernel Classification and Segmentation for Embryo Identification
Dong, D.; Nagasubramanian, K.; Wang, R.; Frei, U. K.; Jubery, T. Z.; Lübberstedt, T.; Ganapathysubramanian, B.
10.1101/2022.11.25.517990 — plant biology — Posted on 2022-11-26
534 An ultra-fast, proteome-wide response to the plant hormone auxin
Roosjen, M.; Kuhn, A.; Mutte, S.; Boeren, S.; Krupar, P.; Koehorst, J. J.; Fendrych, M.; Friml, J.; Weijers, D.
10.1101/2022.11.25.517949 — plant biology — Posted on 2022-11-26
536 Brain-wide measurement of protein turnover with high spatial and temporal resolution
Mohar, B.; Grimm, J. B.; Patel, R.; Brown, T. A.; Tillberg, P.; Lavis, L. D.; Spruston, N.; Svoboda, K.
10.1101/2022.11.12.516226 — neuroscience — Posted on 2022-11-26
538 Imaging crossing fibers in mouse, pig, monkey, and human brain using small-angle X-ray scattering
Georgiadis, M.; Menzel, M.; Reuter, J. A.; Born, D.; Kovacevich, S.; Alvarez, D.; Gao, Z.; Guizar-Sicairos, M.; Weiss, T. M.; Axer, M.; Rajkovic, I.; Zeineh, M. M.
10.1101/2022.09.30.510198 — neuroscience — Posted on 2022-11-26
541 ALT in Pediatric High-Grade Gliomas Can Occur without ATRX Mutation and is Enriched in Patients with Pathogenic Germline MMR Variants
Stundon, J. L.; Ijaz, H.; Gaonkar, K. S.; Kaufman, R. S.; Jin, R.; Karras, A.; Vaksman, Z.; Kim, J.; Corbett, R. J.; Lueder, M. R.; Miller, D. P.; Guo, Y.; Santi, M.; Li, M.; Lopez, G.; Storm, P. B.; Resnick, A. C.; Waanders, A. J.; MacFarland, S. P.; Stewart, D.; Diskin, S. J.; Rokita, J. L.; Cole, K. A.
10.1101/2022.08.05.502870 — cancer biology — Posted on 2022-11-26
545 SNP discovery by exome capture and resequencing in a pea genetic resource collection
AUBERT, G.; Kreplak, J.; Leveugle, M.; Duborjal, H.; Klein, A.; Boucherot, K.; Vieille, E.; Chabert-Martinello, M.; Cruaud, C.; Bourion, V.; Lejeune-Henaut, I.; Pilet-Nayel, M.-L.; Francillonne, N.; Tayeh, N.; Pichon, J.-P.; Riviere, N.; Burstin, J.
10.1101/2022.08.03.502586 — genomics — Posted on 2022-11-26
548 Identification of heterokaryon incompatibility genes in Aspergillus fumigatus highlights a narrow footprint of ancient balancing selection
Auxier, B.; Zhang, J.; Reyes Marquez, F.; Senden, K.; van den Heuvel, J.; Aanen, D. K.; Snelders, E.; Debets, A. J. M.
10.1101/2022.11.25.517501 — evolutionary biology — Posted on 2022-11-26
549 Increased birth rank of homosexual males: disentangling the older brother effect and sexual antagonism hypothesis
Raymond, M.; Turek, D.; Durand, V.; Nila, S.; Suryobroto, B.; Vadez, J.; Barthes, J.; Apostolou, M.; Crochet, P.-A.
10.1101/2022.02.22.481477 — evolutionary biology — Posted on 2022-11-26
550 Deletion of the ion channel Trpm4 increases cardiac inflammatory markers and fibrosis after myocardial infarction in mice
Boukenna, M.; Rougier, J.-S.; Aghagolzadeh, P.; Pradervand, S.; Guichard, S.; Haemmerli, A.-F.; Pedrazzini, T.; Abriel, H.
10.1101/2022.10.24.513479 — molecular biology — Posted on 2022-11-26
551 E. faecalis acquires resistance to antimicrobials and insect immunity via common mechanisms
Wadhawan, A.; Simoes da Silva, C. J.; Nunes, C. D.; Edwards, A. M.; Dionne, M. S.
10.1101/2022.08.17.504265 — microbiology — Posted on 2022-11-26
553 Falcon gut microbiome is shaped by diet and enriched in Salmonella
Ahmad, A.; Ridgeway, S.; Shibl, A. A.; Idaghdour, Y.; Jha, A.
10.1101/2022.11.25.517295 — ecology — Posted on 2022-11-25
556 Uterine NK cells underexpress receptors recognizing HLA-C2 and HLA-G in reproductive failure
Woon, E. V.; Nikolaou, D.; MacLaran, K.; Norman-Taylor, J.; Bhagwat, P.; Cuff, A. O.; Johnson, M. R.; Male, V.
10.1101/2022.11.25.517971 — immunology — Posted on 2022-11-25
558 Mechanisms of ion selectivity and rotor coupling in the bacterial flagellar sodium-driven stator unit
Hu, H.; Popp, P.; Santiveri, M.; Eguiara, A.; Yan, Y.; Liu, Z.; Wadhwa, N.; Wang, Y.; Erhardt, M.; Taylor, N. M. I.
10.1101/2022.11.25.517900 — microbiology — Posted on 2022-11-25
559 Chromatin activity identifies differential gene regulation across human ancestries
Pettie, K. P.; Mumbach, M.; Lea, A. J.; Ayroles, J.; Chang, H. Y.; Kasowski, M.; Fraser, H. B.
10.1101/2022.11.25.517959 — genomics — Posted on 2022-11-25
563 Virulence adaptation of Pseudomonas aeruginosa phospholipase mutant with altered membrane phospholipid composition
Caliskan, M.; Poschmann, G.; Gudzuhn, M.; Waldera-Lupa, D.; Streit, W.; Jaeger, K.-E.; Stuehler, K.; Kovacic, F.
10.1101/2022.11.25.517918 — molecular biology — Posted on 2022-11-25
565 Beyond viral detection: multitrophic effects of covert infection with an RNA virus in medfly.
Hernandez-Pelegrin, L.; Garcia-Martinez, R.; Llacer, E.; Nieves, L.; Llopis-Gimenez, A.; Catala-Oltra, M.; Dembilio, O.; Perez-Hedo, M.; Urbaneja, A.; Ros, V. I. D.; Beitia, F.; Herrero, S.
10.1101/2022.11.25.517915 — microbiology — Posted on 2022-11-25
567 A serine-folate metabolic unit controls resistance and tolerance of infection
Grimes, K.; Beckwith, E. J.; Pearson, W. H.; Jacobson, J.; Chaudhari, S.; Aughey, G. N.; Larrouy-Maumus, G.; Southall, T. D.; Dionne, M. S.
10.1101/2022.11.25.517956 — immunology — Posted on 2022-11-25
568 BDNF and TRiC-inspired Reagents Rescue Cortical Synaptic Deficits in a Mouse Model of Huntington's Disease
Gu, Y.; Pope, A.; Smith-Geater, C.; Carmona, C.; Johnstone, A.; Shi, L.; Chen, X.; Santos, S.; Bacon-Brenes, C. C.; Shoff, T.; Kleczko, K. M.; Frydman, J.; Thompson, L. M.; Mobley, W. C.; Wu, C.
10.1101/2022.11.25.517123 — neuroscience — Posted on 2022-11-25
571 A RAF-like kinase mediates a deeply conserved, ultra-rapid auxin response
Kuhn, A.; Roosjen, M.; Mutte, S.; Dubey, S. M.; Carrillo Carrasco, P.; Monzer, A.; Kohchi, T.; Nishihama, R.; Fendrych, M.; Friml, J.; Sprakel, J.; Weijers, D.
10.1101/2022.11.25.517951 — plant biology — Posted on 2022-11-25
573 A first-in-class Wiskott-Aldrich syndrome protein (WASp) activator with anti-tumor activity in hematological cancers
Spriano, F.; Sartori, G.; Barnabei, L.; Arribas, A. J.; Guala, M.; Del Amo, A. M.; Tomasso, M. R.; Tarantelli, C.; Cascione, L.; Golino, G.; Riveiro, M. E.; Bortolozzi, R.; Lupia, A.; Paduano, F.; Huguet, S.; Rezai, K.; Margheriti, F.; Ventura, P.; Guarda, G.; Costa, G.; Rocca, R.; Cavalli, A.; Viola, G.; Driessen, C.; Zucca, E.; Stathis, A.; Bornhauser, B.; Alcaro, S.; Trapasso, F.; Cristobal, S.; Padrick, S. B.; Pazzi, N.; Cavalli, F.; Bertoni, F.; Gaudio, E.
10.1101/2022.11.25.517686 — cancer biology — Posted on 2022-11-25
577 Transcriptional diversity in synaptic gene sets is sufficient to discriminate cortical neuronal identity
Roig Adam, A.; Martinez Lopez, J.; van der Spek, S.; The SYNGO consortium, ; Sullivan, P. F.; Smit, A.; Verhage, M.; Hjerling-Leffler, J.
10.1101/2022.11.25.517899 — neuroscience — Posted on 2022-11-25
580 Visualization of Incrementally Learned Projection Trajectories for Longitudinal Data
Malepathirana, T. A.; Senanayake, D.; Gautam, V.; Engel, M.; Balez, R.; Lovelace, M.; Sundaram, G.; Heng, B.; Chow, S.; Marquis, C.; Guillemin, G.; Brew, B.; Jagadish, C.; Ooi, L.; Halgamuge, S.
10.1101/2022.11.25.515889 — bioinformatics — Posted on 2022-11-25
584 A simplified, amplicon-based method for whole genome sequencing of human respiratory syncytial viruses
Dong, X.; Deng, Y.-M.; Aziz, A.; Whitney, P.; Clark, J.; Harris, P.; Bautista, C.; Costa, A. M.; Waller, G.; Daley, A. J.; Wieringa, M.; Korman, T.; Barr, I. G.
10.1101/2022.11.24.516812 — genomics — Posted on 2022-11-25
585 An international scholastic network to generate LexA enhancer-trap lines for Drosophila
Kim, E. S.; Rajan, A.; Chang, K.; Gulick, C.; English, E.; Nakada, S.; Beard, C.; O'Connor, S.; Mastroianni, S.; Downey, E.; Feigenbaum, M.; Tolentino, C.; Pace, A.; Khan, M.; Moon, S.; DiPrima, J.; Syed, A.; Lin, F.; Govindarajan, S.; Abukhadra, Y.; Bacon, I.; Beckerle, J.; Bloomfield, O.; Cho, S.; Esi Donkor, N.; Garberg, L.; Harrington, A.; Hoang, M.; Lawani, N.; Noori, A.; Park, E.; Parsons, E.; Oravitan, P.; Chen, M.; Molina, C.; Richmond, C.; Reddi, A.; Huang, J.; Shugrue, C.; Coviello, R.; Unver, S.; Indelicarto, M.; Islamovic, E.; McIlroy, R.; Yang, A.; Hamad, M.; Griffin, E.; Ahmed, Z
10.1101/2022.11.24.517565 — genetics — Posted on 2022-11-25
586 Identification of heterokaryon incompatibility genes in Aspergillus fumigatus highlights a narrow footprint of ancient balancing selection
Auxier, B.; Zhang, J.; Reyes Marquez, F.; van den Heuvel, J.; Senden, K.; Aanen, D. K.; Debets, A. J. M.; Snelders, E.
10.1101/2022.11.25.517501 — evolutionary biology — Posted on 2022-11-25
587 A non-invasive, fast on/off 'Odourgenetic' Method to Manipulate Physiology
ke, c.; cao, g.; Su, S.; Wu, Y.; Xu, X.; Hao, X.; Lu, W.; Li, X.; Wang, L.; Tian, W.; Gao, Y.
10.1101/2022.11.25.517891 — cell biology — Posted on 2022-11-25
590 MMR vaccination induces a trained immunity program characterized by functional and metabolic reprogramming of γδ T cells
Roring, R. J.; Debisarun, P. A.; Botey-Bataller, J.; Suen, K. T.; Bulut, O.; Kilic, G.; Koeken, V. A. C. M.; Sarlea, A.; Bahrar, H.; Dijkstra, H.; Lemmers, H.; Goessling, K. L.; Ruechel, N.; Ostermann, P. N.; Mueller, L.; Schaal, H.; Adams, O.; Borkhardt, A.; Ariyurek, Y.; de Meijer, E. J.; Kloet, S.; ten Oever, J.; Placek, K.; Li, Y.; Netea, M. G.
10.1101/2022.11.24.516894 — immunology — Posted on 2022-11-25
592 Multi-omics analyses of single cell-derived colorectal cancer organoids reveal intratumor heterogeneity and immune response diversity
Yue, J.; Li, J.; Xu, Q.; Ma, Q.; Chen, C.; Liu, S.; Sun, H.-X.; Sui, q.; Mu, F.; Ding, P.; Liu, L.; Perez-Moreno, M.; Zhang, X.
10.1101/2022.11.25.517889 — cancer biology — Posted on 2022-11-25
593 Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits
Mohamed, G. A.; Mahmood, S.; Ognjenovic, N. B.; Lee, M. K.; Wilkins, O. M.; Christensen, B. C.; Muller, K. E.; Pattabiraman, D. R.
10.1101/2022.11.25.517090 — cancer biology — Posted on 2022-11-25
594 Lipid Driven Inter-leaflet Coupling of Plasma Membrane Order Regulates FcεRI Signaling in Mast Cells
Yang, G.-S.; Wagenknecht-Wiesner, A.; Yin, B.; Suresh, P.; London, E.; Baird, B.; Bag, N.
10.1101/2022.11.24.517890 — biophysics — Posted on 2022-11-25
596 ADeS: a deep learning based Apoptosis Detection System for live cell imaging.
Pulfer, A.; Pizzagalli, D. U.; Gagliardi, P. A.; Hinderling, L.; Lopez, P.; Zayats, R.; Barbera, P. C.; Antonello, P.; Segura, M. P.; Giusti, A.; Thelen, M.; Gambardella, L. M.; Murooka, T.; Pertz, O.; Krause, R.; Gonzalez, S. F.
10.1101/2022.11.23.517318 — bioinformatics — Posted on 2022-11-25
598 Developing best practices for genotyping-by-sequencing analysis using linkage maps as benchmarks
Taniguti, C. H.; Taniguti, L. M.; Amadeu, R. R.; Mollinari, M.; Pereira, G. d. S.; Riera-Lizarazu, O.; Lau, J.; Byrne, D.; Gesteira, G. d. S.; Oliveira, T. d. P.; Ferreira, G. C.; Garcia, A. A. F.
10.1101/2022.11.24.517847 — bioinformatics — Posted on 2022-11-25
599 Predicting and Interpreting Protein Developability via Transfer of Convolutional Sequence Representation
Golinski, A. W.; Schmitz, Z. D.; Nielson, G. H.; Johnson, B.; Saha, D.; Appiah, S.; Hackel, B. J.; Martiniani, S.
10.1101/2022.11.21.517400 — bioinformatics — Posted on 2022-11-25
601 RNAlysis: analyze your RNA sequencing data without writing a single line of code
Teichman, G.; Cohen, D.; Ganon, O.; Dunsky, N.; Shani, S.; Gingold, H.; Rechavi, O.
10.1101/2022.11.25.517851 — bioinformatics — Posted on 2022-11-25
603 A multi-omics atlas of the human retina at single-cell resolution
Liang, Q.; Cheng, X.; Wang, J.; Owen, L.; Shakoor, A.; Lillvis, J. L.; Zhang, C.; Farkas, M.; Kim, I.; Li, Y.; DeAngelis, M. M.; Chen, R.
10.1101/2022.11.21.517389 — genomics — Posted on 2022-11-25
604 Efficient Gene Transduction in Pigs and Macaques with the Engineered AAV Vector AAV.GT5 for Hemophilia B Gene Therapy
Kashiwakura, Y.; Endo, K.; Ugajin, A.; Kikuchi, T.; Hishikawa, S.; Nakamura, H.; Katakai, Y.; Baatartsogt, N.; Hiramoto, T.; Hayakawa, M.; Kamoshita, N.; Yamazaki, S.; Kume, A.; Mori, H.; Sata, N.; Sakata, Y.; Muramatsu, S.-i.; Ohmori, T.
10.1101/2022.11.24.517886 — genetics — Posted on 2022-11-25
605 Precision RNAi using synthetic shRNAmir target sites
Hoffmann, T.; Hörmann, A.; Corcokovic, M.; Zmajkovic, J.; Hinterndorfer, M.; Salkanovic, J.; Spreitzer, F.; Köferle, A.; Gitschtaler, K.; Popa, A.; Oberndorfer, S.; Andersch, F.; Schaefer, M.; Fellner, M.; Budano, N.; Ruppert, J. G.; Chetta, P.; Wurm, M.; Zuber, J.; Neumüller, R. A.
10.1101/2022.11.24.517802 — genetics — Posted on 2022-11-25
607 Induced responses contribute to rapid plant adaptation to herbivory
Malacrino, A.; Böttner, L.; Nouere, S.; Huber, M.; Schäfer, M.; Xu, S.
10.1101/2022.11.24.517793 — evolutionary biology — Posted on 2022-11-25
610 Nutritional and host environments determine community ecology and keystone species in a synthetic gut bacterial community
Weiss, A. S.; Niedermeier, L. S.; von Strempel, A.; Burrichter, A. G.; Ring, D.; Meng, C.; Kleigrewe, K.; Lincetto, C.; Hübner, J.; Stecher, B.
10.1101/2022.11.24.516551 — ecology — Posted on 2022-11-25
611 Spatial scale influences taxon conservation in the eukaryotic virome of a mosquito
Gil, P.; Exbrayat, A.; Loire, E.; Rakotoarivoany, I.; Charriat, F.; Baldet, T.; Boisseau, M.; Marie, A.; Frances, B.; L'Ambert, G.; Bessat, M.; Otify, Y.; Goffredo, M.; Mancini, G.; Busquets, N.; Birnberg, L.; Talavera, S.; Aranda, C.; Ayari-Fakhfakh, E. S.; Mejri, S.; Sghaier, S.; Bennouna, A.; El Rhaffouli, H.; Balenghien, T.; Chlyeh, G.; Fihri, O. F.; Reveillaud, J.; Simonin, Y.; Eloit, M.; Gutierrez, S.
10.1101/2022.11.23.517782 — ecology — Posted on 2022-11-25
616 Gasdermin D is the only Gasdermin that provides non-redundant protection against acute Salmonella gut infection
Fattinger, S. A.; Maurer, L.; Geiser, P.; Enz, U.; Ganguillet, S.; Gul, E.; Kroon, S.; Demarco, B.; Furter, M.; Barthel, M.; Pelczar, P.; Shao, F.; Broz, P.; Sellin, M. E.; Hardt, W.-D.
10.1101/2022.11.24.517575 — immunology — Posted on 2022-11-25
617 Inhibition of myeloperoxidase prevents thoracic aortic aneurysm formation in Marfan mice
Mehrkens, D.; Nettersheim, F. S.; Ballmann, F.; Bastigkeit, J.; Brueckner, A.; Dohr, J.; Geissen, S.; De Vore, L.; Schelemei, P.; Picard, F. R.; Kochen, M.; Braumann, S.; Kreuzberg, W.; Hof, A.; Guthoff, H.; Brandtner, A.; Quaye Mensah, B.; Groenink, M.; van Andel, M.; Mieremet, A.; Pfeiler, S.; Gerdes, N.; Floegel, U.; Zimmermann, L.-M.; Sengle, G.; Eich, M.-L.; Schoemig-Mariefka, B.; Adam, M.; Fleischmann, B. K.; Wenzel, D.; de Waard, V.; Klinke, A.; Baldus, S.; Mollenhauer, M.; Winkels, H.
10.1101/2022.11.24.517172 — immunology — Posted on 2022-11-25
623 Ethylene-mediated phosphorylation of ORESARA1 induces sequential leaf death during flooding in Arabidopsis
Rankenberg, T.; van Veen, H.; Sedaghatmehr, M.; Liao, C.-Y.; Devaiah, M. B.; Balazadeh, S.; Sasidharan, R.
10.1101/2022.11.23.517613 — plant biology — Posted on 2022-11-25
624 Completing the TRB family: newly characterized members show ancient evolutionary origins and distinct localization, yet similar interactions
Kusova, A.; Steinbachova, L.; Prerovska, T.; Drabkova, L. Z.; Palecek, J.; Khan, A.; Rigoova, G.; Gadiou, Z.; Jourdain, C.; Sticker, T.; Schubert, D.; Honys, D.; Schrumpfova, P. P.
10.1101/2022.11.23.517682 — plant biology — Posted on 2022-11-25
625 Organization, genomic targeting and assembly of three distinct SWI/SNF chromatin remodeling complexes in Arabidopsis
Li, C.; Fu, W.; Yu, Y.; Shu, J.; Yu, Z.; Zhu, T.; Zhong, Y.; Zhang, Z.; Liang, Z.; Cui, Y.; Chen, C.
10.1101/2022.11.24.517835 — plant biology — Posted on 2022-11-25
626 Mechanical wounding impacts the growth versus defence balance in tomato (Solanum lycopersicum)
Cunha, A. F. A.; Rodrigues, P. H. D.; Anghinoni, A. C.; Paiva, V. J. d.; Pinheiro, D. G. d. S.; Campos, M. L.
10.1101/2022.11.24.517841 — plant biology — Posted on 2022-11-25
627 Calredoxin regulates the chloroplast NADPH-dependent thioredoxin reductase in Chlamydomonas reinhardtii
Zinzius, K.; Marchetti, G. M.; Fischer, R.; Milrad, Y.; Oltmanns, A.; Kelterborn, S.; Yacoby, I.; Hegemann, P.; Scholz, M.; Hippler, M.
10.1101/2022.11.22.517551 — plant biology — Posted on 2022-11-25
629 Monitoring the intestinal magnetic field with optically pumped atomic magnetometers
Sun, C.; Zhao, B.; Wu, T.; Zhang, J.; Leng, Y.; Guo, H.; CREAM Bioelectromagnetism Group,
10.1101/2022.11.23.517508 — physiology — Posted on 2022-11-25
630 3DProtDTA: the deep learning model for drug-target affinity prediction based on the residue-level protein graphs
Voitsitskyi, T.; Stratiichuk, R.; Koleiev, I.; Popryho, L.; Ostrovsky, Z.; Henitsoi, P.; Khropachev, I.; Vozniak, V.; Zhytar, R.; Nechepurenko, D.; Yesylevskyy, S.; Nafiev, A.; Starosyla, S.
10.1101/2022.11.24.517815 — pharmacology and toxicology — Posted on 2022-11-25
631 Platelets favor the outgrowth of established metastases
Garcia-Leon, M. J.; Lefebvre, O.; Follain, G.; Mouriaux, C.; Busnelli, I.; Larnicol, A.; Colin, F.; Mittelheisser, V.; Peralta, M.; Bourdon, C.; Samaniego, R.; Jandrot-Perrus, M.; Mangin, P. H.; Goetz, J. G.
10.1101/2022.10.28.514195 — cancer biology — Posted on 2022-11-25
633 ExposomeX: Integrative Exposomic Platform Expediates Discovery of "Exposure-Biology-Disease" Nexus
Wang, B.; Lan, C.; Zhang, G.; Ren, M.; Feng, Y.; Gao, N.; Lin, W.; Jiangtulu, B.; Liu, Z.; Shao, X.; Su, S.; Wang, Y.; Wang, H.; Zhao, F.; Peng, B.; Ji, X.; Chen, X.; Nian, M.; Fang, M.
10.1101/2022.11.23.517586 — bioinformatics — Posted on 2022-11-25
637 Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands
Fierro, F.; Peri, L.; Huebner, H.; Tabor-Schkade, A.; Waterloo, L.; Loeber, S.; Pfeiffer, T.; Dingjan, T.; Margulis, E.; Gmeiner, P.; Niv, M. Y.
10.1101/2022.11.24.517821 — bioinformatics — Posted on 2022-11-25
638 SCALA: A web application for multimodal analysis of single cell next generation sequencing data
Tzaferis, C.; Karatzas, E.; Baltoumas, F. A.; Pavlopoulos, G. A.; Kollias, G.; Konstantopoulos, D.
10.1101/2022.11.24.517826 — bioinformatics — Posted on 2022-11-25
640 Predicting Lung Cancer in Korean Never-Smokers with Polygenic Risk Scores
Kim, J.; Park, Y. S.; Kim, J. H.; Hong, Y.-C.; Kim, Y.-C.; Oh, I.-J.; Jee, S. H.; Ahn, M.-J.; Kim, J.-W.; Yim, J.-J.; Won, S.
10.1101/2022.11.23.515119 — bioinformatics — Posted on 2022-11-25
643 Micromagnetic Stimulation (μMS) Dose-Response of the Rat Sciatic Nerve
Saha, R.; Sanger, Z.; Bloom, R.; Benally, O.; Wu, K.; Tonini, D.; Low, W. C.; Keirstead, S.; Netoff, T. I.; Wang, J.-P.
10.1101/2022.11.23.517726 — bioengineering — Posted on 2022-11-25
645 A multi-layer mean-field model for the cerebellar cortex: design, validation, and prediction
Lorenzi, R. M.; Geminiani, A.; Zerlaut, Y.; Destexhe, A.; Gandini Wheeler-Kingshott, C. A. M.; Palesi, F.; Casellato, C.; D'Angelo, E.
10.1101/2022.11.24.517708 — bioengineering — Posted on 2022-11-25
648 An in vivo massively parallel platform for deciphering tissue-specific regulatory function
Brown, A. R.; Fox, G. A.; Kaplow, I. M.; Lawler, A. J.; Phan, B. N.; Wirthlin, M. E.; Ramamurthy, E.; May, G. E.; Chen, Z.; Su, Q.; McManus, C. J.; Pfenning, A. R.
10.1101/2022.11.23.517755 — genomics — Posted on 2022-11-25
651 Natural genetic variation in the pheromone production of C. elegans
Lee, D.; Fox, B. W.; Palomino, D. C. F.; Panda, O.; Tenjo, F. J.; Evans, K. S.; Stevens, L.; Koury, E.; Rodrigues, P. R.; Kolodziej, A. R.; Schroeder, F. C.; Andersen, E. C.
10.1101/2022.11.23.517769 — evolutionary biology — Posted on 2022-11-25
653 Recent evolution of a maternally-acting sex-determining supergene in a fly with single-sex broods
Baird, R. B.; Urban, J. M.; Mongue, A. J.; Jaron, K. S.; Hodson, C. N.; Grewoldt, M.; Martin, S. H.; Ross, L.
10.1101/2022.11.24.517840 — evolutionary biology — Posted on 2022-11-25
656 Universal microbial reworking of dissolved organic matter along environmental gradients
Freeman, E. C.; Emilson, E. J.; Dittmar, T.; Braga, L. P.; Emilson, C. E.; Goldhammer, T.; Martineau, C.; Singer, G.; Tanentzap, A. J.
10.1101/2022.11.23.517109 — ecology — Posted on 2022-11-25
658 Maintaining structural and functional homeostasis of the Drosophila respiratory epithelia requires stress-modulated JAK/STAT activity
Niu, X.; Fink, C.; Kallsen, K.; Shi, L.; Mincheva, V.; Franzenburg, S.; Prange, R. D.; Bossen, J.; Heine, H.; Roeder, T.
10.1101/2020.06.19.160929 — cell biology — Posted on 2022-11-25
660 Genetic insights into the causal relationship between physical activity and cognitive functioning
Cheval, B.; Darrous, L.; Choi, K.; Klimentidis, Y.; Raichlen, D.; Alexander, G.; Cullati, S.; Kutalik, Z.; Boisgontier, M. P.
10.1101/2020.10.16.342675 — neuroscience — Posted on 2022-11-25
662 A Multimodal Atlas of Tumor Metabolism Reveals the Architecture of Gene-Metabolite Co-regulation
Benedetti, E.; Liu, E. M.; Tang, C.; Kuo, F.; Buyukozkan, M.; Park, T.; Park, J.; Correa, F.; Hakimi, A. A.; Intlekofer, A. M.; Krumsiek, J.; Reznik, E.
10.1101/2022.11.23.517549 — cancer biology — Posted on 2022-11-25
663 BLEND: A Fast, Memory-Efficient, and Accurate Mechanism to Find Fuzzy Seed Matches in Genome Analysis
Firtina, C.; Park, J.; Alser, M.; Kim, J. S.; Senol Cali, D.; Shahroodi, T.; Mansouri Ghiasi, N.; Singh, G.; Kanellopoulos, K.; Alkan, C.; Mutlu, O.
10.1101/2022.11.23.517691 — bioinformatics — Posted on 2022-11-25
664 MSdb: an integrated expression atlas of human musculoskeletal system
Lin, J.; Tian, R.; Xue, Z.; Ruan, D.; Chen, P.; Xu, Y.; Dai, C.; Shen, W.; Ouyang, H.; Liu, W.
10.1101/2022.11.23.517756 — bioinformatics — Posted on 2022-11-25
668 Miniature spatial transcriptomics for studying parasite-endosymbiont relationships at the micro scale
Sounart, H.; Voronin, D.; Masarapu, Y.; Chung, M.; Saarenpaa, S.; Ghedin, E.; Giacomello, S.
10.1101/2022.11.23.517653 — genomics — Posted on 2022-11-25
669 Polygenic Prediction of Molecular Traits using Large-Scale Meta-analysis Summary Statistics
Pain, O.; Gerring, Z. F.; Derks, E. F.; Wray, N. R.; Gusev, A.; Al-Chalabi, A.
10.1101/2022.11.23.517213 — genomics — Posted on 2022-11-25
670 Genomic and machine learning-based screening of aquaculture associated introgression into at-risk wild North American Atlantic salmon (Salmo salar) populations.
Nugent, C. M.; Kess, T.; Brachmann, M. K.; Langille, B. L.; Holborn, M. K.; Beck, S. V.; Smith, N.; Duffy, S.; Lehnert, S. J.; Wringe, B.; Bentzen, P.; Bradbury, I. R.
10.1101/2022.11.23.517511 — genomics — Posted on 2022-11-25
672 Patterns of genetic differentiation imply distinct evolutionary histories of the sibling mosquito species Anopheles messeae and Anopheles daciae in Eurasia
Brusentsov, I. I.; Gordeev, M. I.; Yurchenko, A. A.; Karagodin, D. A.; Moskaev, A. V.; Hodge, J. M.; Burlak, V. A.; Artemov, G. N.; Sibataev, A. K.; Becker, N.; Sharakhov, I. V.; Baricheva, E. M.; Sharakhova, M. V.
10.1101/2022.11.23.517664 — evolutionary biology — Posted on 2022-11-25
675 Spatial expression of an mRNA encoding Tie2-agonist in the capillary endothelium of the lung prevents pulmonary vascular leakage
Radloff, K.; Gutbier, B.; Dunne, C. M.; Moradian, H.; Gossen, M.; Ahrens, K. M.; Kneller, L.; Wang, Y.; Moga, A.; Gkionis, L.; Keil, O.; Fehring, V.; Tondera, D.; Giese, K.; Santel, A.; Kaufmann, J.; Witzenrath, M.
10.1101/2022.10.12.511878 — molecular biology — Posted on 2022-11-25
676 Plasticity in centromere organization: Holocentromeres can consist of merely a few megabase-sized satellite arrays
Kuo, Y.-T.; Camara, A. S.; Schubert, V.; Neumann, P.; Macas, J.; Melzer, M.; Chen, J.; Fuchs, J.; Abel, S.; Klocke, E.; Huettel, B.; Himmelbach, A.; Demidov, D.; Dunemann, F.; Mascher, M.; Ishii, T.; Marques, A.; Houben, A.
10.1101/2022.11.23.516916 — plant biology — Posted on 2022-11-25
677 Functional evolutionary convergence of long noncoding RNAs involved in embryonic development.
Olazagoitia-Garmendia, A.; Senovilla-Ganzo, R.; Garcia-Moreno, F.; Castellanos-Rubio, A.
10.1101/2022.06.15.496228 — molecular biology — Posted on 2022-11-25
678 Functional and microstructural plasticity following social and interoceptive mental training.
Valk, S. L.; Kanske, P.; Park, B.-y.; Hong, S.-J.; Boeckler, A.; Trautwein, F.-M.; Bernhardt, B. C.; Singer, T.
10.1101/2020.11.11.377895 — neuroscience — Posted on 2022-11-25
685 Not all pathways are the same - unique adaptations to submerged environments emerge from comparative seagrass genomics
Bayer, P. E.; Fraser, M. W.; Martin, B. C.; Petereit, J.; Severn-Ellis, A. A.; Sinclair, E. A.; Batley, J.; Kendrick, G. A.; Edwards, D.
10.1101/2022.11.22.517588 — plant biology — Posted on 2022-11-24
687 Metabolic collaboration between cells in the tumor microenvironment has a negligible effect on tumor growth
Gustafsson, J.; Roshanzamir, F.; Hagnestal, A.; Patel, S. M.; Daudu, O. I.; Becker, D. F.; Robinson, J. L.; Nielsen, J.
10.1101/2022.02.08.479584 — cancer biology — Posted on 2022-11-24
688 miR-210 expression is strongly hypoxia-induced in anaplastic thyroid cancer cell lines and is associated with extracellular vesicles & Argonaute-2
Powell, B. H.; Turchinovich, A.; Wang, Y.; Gololobova, O.; Buschmann, D.; Zeiger, M. A.; Umbricht, C. B.; Witwer, K. W.
10.1101/2022.11.23.515840 — cancer biology — Posted on 2022-11-24
690 AirLift: A Fast and Comprehensive Technique for Remapping Alignments between Reference Genomes
Kim, J. S.; Firtina, C.; Cavlak, M. B.; Cali, D. S.; Hajinazar, N.; Alser, M.; Alkan, C.; Mutlu, O.
10.1101/2021.02.16.431517 — bioinformatics — Posted on 2022-11-24
692 OpenFold: Retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization
Ahdritz, G.; Bouatta, N.; Kadyan, S.; Xia, Q.; Gerecke, W.; O'Donnell, T. J.; Berenberg, D.; Fisk, I.; Zanichelli, N.; Zhang, B.; Nowaczynski, A.; Wang, B.; Stepniewska-Dziubinska, M. M.; Zhang, S.; Ojewole, A.; Guney, M. E.; Biderman, S.; Watkins, A. M.; Ra, S.; Lorenzo, P. R.; Nivon, L.; Weitzner, B.; Ban, Y.-E. A.; Sorger, P. K.; Mostaque, E.; Zhang, Z.; Bonneau, R.; AlQuraishi, M.
10.1101/2022.11.20.517210 — bioinformatics — Posted on 2022-11-24
695 A dopaminergic memory circuit controls acute valence
Mohammad, F.; Mai, Y.; Ho, J.; Zhang, X.; Ott, S.; Stewart, J. C.; Claridge-Chang, A.
10.1101/2022.11.23.517775 — animal behavior and cognition — Posted on 2022-11-24
697 Developing a temperature-inducible transcriptional rheostat in Neurospora crassa
Tabilo-Agurto, C.; Del Rio-Pinilla, V.; Eltit-Villarroel, V.; Goity, A.; Munoz-Guzman, F.; Larrondo, L. F.
10.1101/2022.11.24.517854 — molecular biology — Posted on 2022-11-24
700 Characterization of Genomic Diversity In Bacteriophages Infecting Rhodococcus
Garza, D. R.; Di Blasi, D.; Bruns, J. A.; Empson, B.; Ghannam, M.; Light, I.; Castillo, S.; Quijada, B.; Zorawik, M.; Garcia-Vedrenne, A. E.; Freise, A. C.
10.1101/2022.11.23.517428 — microbiology — Posted on 2022-11-24
701 Unique genomic sequences in novel Mycobacterium avium subsp. hominissuis lineage enabled fine scale tracing the transmission route during pig movement
Komatsu, T.; Ohya, K.; Ota, A.; Nishiuchi, Y.; Yano, H.; Matsuo, K.; Odoi, J. O.; Suganuma, S.; Sawai, K.; Hasebe, A.; Asai, T.; Yanai, T.; Fukushi, H.; Wada, T.; Yoshida, S.; Arikawa, K.; Ito, T.; Kawai, M.; Ato, M.; Baughn, A. D.; Iwamoto, T.; MARUYAMA, F.
10.1101/2022.04.04.487006 — microbiology — Posted on 2022-11-24
702 An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission
Li, W.; Wang, T.; Mekhemadhom Rajendrakumar, A.; Acharya, G.; Miao, Z.; Varghese, B. P.; Yu, H.; Dhakal, B.; LeRoith, T.; Tuo, W.; Zhu, X.
10.1101/2022.11.23.517678 — immunology — Posted on 2022-11-24
703 Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity
Textor, J.; Buytenhuijs, F.; Rogers, D.; Mallet Gauthier, E.; Sultan, S.; Wortel, I. M. N.; Kalies, K.; Fähnrich, A.; Pagel, R.; Melichar, H.; Westermann, J.; Mandl, J. N.
10.1101/2022.11.23.517563 — immunology — Posted on 2022-11-24
710 retro-Tango enables versatile retrograde circuit tracing in Drosophila
Sorkac, A.; Mosneanu, R. A.; Crown, A. M.; Savas, D.; Okoro, A. M.; Talay, M.; Barnea, G.
10.1101/2022.11.24.517859 — neuroscience — Posted on 2022-11-24
713 All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals
Bergs, A. C.; Liewald, J. F.; Rodriguez-Rozada, S.; Liu, Q.; Wirt, C.; Bessel, A.; Zeitzschel, N.; Durmaz, H.; Nozownik, A.; Jospin, M.; Vierock, J.; Bargmann, C.; Hegemann, P.; Wiegert, J. S.; Gottschalk, A.
10.1101/2022.06.03.494532 — neuroscience — Posted on 2022-11-24
715 Rat prefrontal cortex is not crucial for cognitive control during spatial learning and memory
Park, E.; Reilly, K. O.; Grubbs, G.; Taborga, D.; Nicholas, K.; Ahmeda, A. S.; Ruiz, N.; Kim, N.; Segura-Carrillo, S.; Fenton, A. A.
10.1101/2019.12.20.884262 — neuroscience — Posted on 2022-11-24
718 The role of the thalamus in human reinforcement learning
Collomb-Clerc, A.; Gueguen, M. C.; Minotti, L.; Kahane, P.; Navarro, V.; Bartolomei, F.; Carron, R.; Regis, J.; Chabardes, S.; Palminteri, S.; Bastin, J.
10.1101/2022.11.23.517731 — neuroscience — Posted on 2022-11-24
721 Acinar-to-ductal metaplasia in the pancreas requires a glycolytic switch and functional mitochondria
Neuss, T.; Wirges, N.; Chen, M.-C.; Usluer, S.; Oellinger, R.; Lier, S.; Dudek, M.; Madl, T.; Jastroch, M.; Steiger, K.; Schmitz, W.; Einwaechter, H.; Schmid, R. M.
10.1101/2022.06.27.495427 — cancer biology — Posted on 2022-11-24
726 A preclinical model of THC edibles that produces high-dose cannabimimetic responses
English, A.; Uittenbogaard, F.; Torrens, A.; Sarroza, D.; Slaven, A.; Piomelli, D.; Bruchas, M.; Stella, N.; Land, B. B.
10.1101/2022.11.23.517743 — animal behavior and cognition — Posted on 2022-11-24
727 Epigenomic tomography for probing spatially-defined molecular state in the brain
Liu, Z.; Deng, C.; Zhou, Z.; Xiao, Y.; Jiang, S.; Zhu, B.; Naler, L. B.; Jia, X.; Yao, D. D.; Lu, C.
10.1101/2022.11.24.517865 — genomics — Posted on 2022-11-24
728 Probing the genetic code and impacts of mistranslation using tRNAAla anticodon variants
Cozma, E.; Rao, M.; Dusick, M.; Genereaux, J.; Rodriguez-Mias, R. A.; Villen, J.; Brandl, C. J.; Berg, M. D.
10.1101/2022.11.23.517754 — molecular biology — Posted on 2022-11-24
729 Copiotrophs dominate rhizosphere microbiomes and growth rate potential is a major factor explaining the rhizosphere effect
Lopez, J. L.; Pappas, N.; Poppeliers, S. W.; Sanchez-Gil, J. J.; Fourie-Fouche, A.; de Jonge, R.; Dutilh, B. E.
10.1101/2022.11.24.517860 — microbiology — Posted on 2022-11-24
732 Naturalistic viewing: An open-access dataset using simultaneous EEG-fMRI
Telesford, Q. K.; Gonzalez-Moreira, E.; Xu, T.; Tian, Y.; Colcombe, S. J.; Cloud, J.; Russ, B. E.; Falchier, A.; Nentwich, M.; Madsen, J.; Parra, L. C.; Schroeder, C.; Milham, M.; Franco, A. R.
10.1101/2022.11.23.517540 — neuroscience — Posted on 2022-11-24
734 Fast imaging of millimeter-scale areas with beam deflection transmission electron microscopy
Zheng, Z.; Own, C. S.; Wanner, A. A.; Koene, R. A.; Hammerschmith, E. W.; Silversmith, W. M.; Kemnitz, N.; Tank, D. W.; Seung, H. S.
10.1101/2022.11.23.517701 — neuroscience — Posted on 2022-11-24
735 Integration of optic flow into the sky compass network in the brain of the desert locust
Zittrell, F.; Pabst, K.; Carlomagno, E.; Rosner, R.; Pegel, U.; Endres, D. M.; Homberg, U.
10.1101/2022.11.24.517785 — neuroscience — Posted on 2022-11-24
736 Poly ADP-Ribose Signaling is Dysregulated in Huntington Disease Patients
Maiuri, T.; Bazan, C. B.; Harding, R. J.; Begeja, N.; Kam, T.-I.; Byrne, L. M.; Rodrigues, F. B.; Warner, M. M.; Neuman, K.; Mansoor, M.; Badiee, M.; Dasovich, M.; Leung, A. K.; Andres, S. N.; Wild, E. J.; Dawson, T. M.; Dawson, V. L.; Arrowsmith, C. H.; Truant, R.
10.1101/2022.11.23.517669 — neuroscience — Posted on 2022-11-24
738 Activity-regulated gene expression across cell types of the mouse hippocampus
Nelson, E. D.; Maynard, K. R.; Nicholas, K. R.; Tran, M. N.; Divecha, H. R.; Collado-Torres, L.; Hicks, S. C.; Martinowich, K.
10.1101/2022.11.23.517593 — neuroscience — Posted on 2022-11-24
739 Hierarchical Modular Structure of the Drosophila Connectome
Kunin, A. B.; Guo, J.; Bassler, K. E.; Pitkow, X.; Josic, K.
10.1101/2022.11.23.517722 — neuroscience — Posted on 2022-11-24
740 The Neural Correlates of Arousal: The Ventral Posterolateral Nucleus-Global Transient Co-Activation
Han, J.; Xie, Q.; Wu, X.; Huang, Z.; Tanabe, S.; Fogel, S.; Hudetz, A. G.; Wu, H.; Northoff, G.; Mao, Y.; He, S.; Qin, P.
10.1101/2022.11.23.517776 — neuroscience — Posted on 2022-11-24
742 The AUX1-AFB1-CNGC14 module establishes longitudinal root surface pH profile
Serre, N. B.; Wernerova, D.; Vittal, P.; Dubey, S. M.; Medvecka, E.; Jelinkova, A.; Petrasek, J.; Grossmann, G.; Fendrych, M.
10.1101/2022.11.23.517700 — plant biology — Posted on 2022-11-24
744 Optimal clustering for quantum refinement of biomolecular structures: Q|R#4
Wang, Y.; Kruse, H.; Moriarty, N. W.; Waller, M. P.; Afonine, P. V.; Biczysko, M.
10.1101/2022.11.24.517825 — biochemistry — Posted on 2022-11-24
745 Multiplexed selectivity screening of anti-GPCR antibodies
Dahl, L.; Kotliar, I.; Bendes, A.; Dodig-Crnkovic, T.; Fromm, S.; Elofsson, A.; Uhlen, M.; Sakmar, T. P.; Schwenk, J.
10.1101/2022.11.24.517810 — biochemistry — Posted on 2022-11-24
746 Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10
Ivaldo, C.; Passalacqua, M.; Furfaro, A. L.; d'Abramo, C.; Ruiz, S.; Chatterjee, P. K.; Metz, C. N.; Nitti, M.; Marambaud, P.
10.1101/2022.11.23.517709 — cell biology — Posted on 2022-11-24
749 Genomics of Preaxostyla Flagellates Illuminates Evolutionary Transitions and the Path Towards Mitochondrial Loss
Novak, L. V. F.; Treitli, S. C.; Pyrih, J.; Hałakuc, P.; Pipaliya, S. V.; Vacek, V.; Brzon, O.; Soukal, P.; Eme, L.; Dacks, J. B.; Karnkowska, A.; Elias, M.; Hampl, V.
10.1101/2022.11.24.517819 — microbiology — Posted on 2022-11-24
752 Dynamics of methane cycling microbiome during methane flux hot moments from riparian buffer systems
Obregon, D.; Mafa-Attoye, T.; Baskerville, M.; Mitter, E.; Fonseca de Souza, L.; Oelbermann, M.; Thevathasan, N.; Tsai, S. M.; Dunfield, K. E.
10.1101/2022.11.24.517857 — microbiology — Posted on 2022-11-24
754 CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake
Nikolaou, S.; Juin, A.; Whitelaw, J. A.; Paul, N. R.; Fort, L.; Nixon, C.; Spence, H. J.; Bryson, S.; Machesky, L. M.
10.1101/2022.11.23.517689 — cancer biology — Posted on 2022-11-24
756 Platelet pannexin-1 channels modulate inflammation during abdominal aortic aneurysm formation
Metz, L. M.; Feige, T.; de Biasi, L.; Ehrenberg, A.; Mulorz, J.; Toska, L. M.; Reusswig, F.; Quast, C.; Gerdes, N.; Kelm, M.; Schelzig, H.; Elvers, M.
10.1101/2022.11.23.517652 — cell biology — Posted on 2022-11-24
757 Inhibition of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosis
Nemade, H. N.; Mehrkens, D.; Lottermoser, H. S.; Yilmaz, Z. E.; Schelemei, P.; Picard, F. R.; Geissen, S.; Schwab, G. F.; Hoyer, F. F.; Guthoff, H.; Hof, A.; Nettersheim, F. S.; Sachinidis, A.; Winkels, H.; Baldus, S.; Pasparakis, M.; Adam, M.; Mollenhauer, M.
10.1101/2022.11.24.517638 — cell biology — Posted on 2022-11-24
758 Autolysosomal exocytosis of lipids protect neurons from ferroptosis
Ralhan, I.; Chang, J.; Moulton, M. J.; Goodman, L. D.; Lee, N. Y.; Plummer, G.; Pasolli, H. A.; Matthies, D.; Bellen, H. J.; Ioannou, M. S.
10.1101/2022.11.24.517842 — cell biology — Posted on 2022-11-24
759 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation
Ast, T.; Itoh, Y.; Sadre, S.; McCoy, J. G.; Namkoong, G.; Chicherin, I.; Joshi, P. R.; Kamenski, P.; Suess, D. L. M.; Amunts, A.; Mootha, V. K.
10.1101/2022.11.24.517765 — cell biology — Posted on 2022-11-24
760 Impairment of lipid homoeostasis causes accumulation of protein aggregates in the lysosome
Yong, J.; Villalta, J. E.; Vu, N.; Kukurugya, M. A.; Bennett, B. D.; Lopez, M. P.; Lazzari-Dean, J. R.; Hake, K.; Jan, C. H.
10.1101/2022.11.23.517579 — cell biology — Posted on 2022-11-24
765 Mapping the content of comments on bioRxiv and medRxiv preprints
Carneiro, C. F. D.; Costa, G.; Neves, K.; Abreu, M. B.; Tan, P. B.; Rayee, D.; Boos, F.; Andrejew, R.; Lubiana, T.; Malicki, M.; Amaral, O. B.
10.1101/2022.11.23.517621 — scientific communication and education — Posted on 2022-11-24
766 Individual identity and environmental conditions explain different aspects of sleep behaviour in wild boar
Mortlock, E.; Silovsky, V.; Guldenpfennig, J.; Faltusova, M.; Olejarz, A.; Borger, L.; Jezek, M.; Jennings, D. J.; Capellini, I.
10.1101/2022.11.23.517569 — ecology — Posted on 2022-11-24
767 MERISTEM-DEFECTIVE/DEFECTIVELY ORGANIZED TRIBUTARIES2 regulates the balance between stemness and differentiation in the root meristem through RNA splicing control.
Thompson, H. L.; Shen, W.; Matus, R.; Kakkar, M.; Jones, C.; Dolan, D.; Grellscheid, S.; Yang, X.; Zhang, N.; Mozaffari-Jovin, S.; Chen, C.; Zhang, X.; Topping, J. F.; Lindsey, K.
10.1101/2022.11.23.517632 — plant biology — Posted on 2022-11-24
769 Interactive explainable AI platform for graph neural networks
Beinecke, J. M.; Saranti, A.; Angerschmid, A.; Pfeifer, B.; Klemt, V.; Holzinger, A.; Hauschild, A.-C.
10.1101/2022.11.21.517358 — bioinformatics — Posted on 2022-11-24
775 Neuronal IL-17 controls C. elegans developmental diapause through p53/CEP-1
Godthi, A.; Srijit, D.; Cruz-Corchado, J.; Deonarine, A.; Misel-Wuchter, K.; Issuree, P. D.; Prahlad, V.
10.1101/2022.11.22.517560 — developmental biology — Posted on 2022-11-24
778 Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms
Rodriguez-Blazquez, A.; Carabias, A.; Moran-Vaquero, A.; de Cima, S.; Luque-Ortega, J. R.; Alfonso, C.; Schuck, P.; Manso, J. A.; Macedo-Ribeiro, S.; Guerrero, C.; de Pereda, J. M.
10.1101/2022.11.24.515150 — molecular biology — Posted on 2022-11-24
779 Cytokine profiles in adults with imported malaria: insights from the PALUREA cohort study
de Roquetaillade, C.; Laouenan, C.; Mira, J.-P.; Roy, C.; Thuong, M.; Azoulay, E.; Gruson, D.; Jacobs, F.; Chommeloux, J.; Raffi, F.; Hocqueloux, L.; Imbert, P.; Jeantils, V.; Delassus, J.-L.; Matheron, S.; Fitting, C.; Timsit, J.-F.; Bruneel, F.
10.1101/2022.11.23.517616 — immunology — Posted on 2022-11-24
780 Spatial transcriptomics of T and B cell receptors uncovers lymphocyte clonal dynamics in human tissue.
Engblom, C.; Thrane, K.; Lin, Q.; Andersson, A.; Toosi, H.; Chen, X.; Steiner, E.; Mantovani, G.; Hagemann-Jensen, M.; Saarenpaa, S.; Jangard, M.; Michaelsson, J.; Hartman, J.; Lagergren, J.; Mold, J. E.; Lundeberg, J.; Frisen, J.
10.1101/2022.11.22.516865 — immunology — Posted on 2022-11-24
781 Characterization of spatiotemporal dynamics in EEG data during picture naming with optical flow patterns
Volpert, V.; Xu, B.; Tchechmedjiev, A.; Harispe, S.; Aksenov, A.; Mesnildrey, Q.; Beuter, A.
10.1101/2022.11.24.517789 — neuroscience — Posted on 2022-11-24
782 Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Sampedro-Castaneda, M.; Baltussen, L. L.; Lopes, A. T.; Qiu, Y.; Sirvio, L.; Mihaylov, S. R.; Claxton, S.; Richardson, J. C.; Lignani, G.; Ultanir, S. K.
10.1101/2022.11.24.517538 — neuroscience — Posted on 2022-11-24
784 Brain criticality predicts individual synchronization levels in humans
Fusca, M.; Siebenhuhner, F.; Wang, S. H.; Myrov, V.; Arnulfo, G.; Nobili, L.; Palva, J. M.; Palva, S.
10.1101/2022.11.24.517800 — neuroscience — Posted on 2022-11-24
785 Holistic monitoring of freshwater and terrestrial vertebrates by camera trapping and environmental DNA
Holm, A. M. R.; Knudsen, S. W.; Maansson, M.; Pedersen, D. E.; Nordfoss, P. H.; Johansson, D. K.; Gramsbergen, M.; Havmoller, R. W.; Sigsgaard, E. E.; Thomsen, P. F.; Olsen, M. T.; Moller, P. R.
10.1101/2022.11.23.517571 — zoology — Posted on 2022-11-24
790 Node-degree aware edge sampling mitigates inflated classification performance in biomedical graph representation learning
Cappelletti, L.; Rekerle, L.; Fontana, T.; Hansen, P.; Casiraghi, E.; Ravanmehr, V.; Mungall, C. J.; Yang, J.; Spranger, L.; Karlebach, G.; Caufield, J. H.; Carmody, L.; Coleman, B.; Oprea, T.; Reese, J.; Valentini, G.; Robinson, P. N.
10.1101/2022.11.21.517376 — bioinformatics — Posted on 2022-11-24
793 Peptide-MHC Structure Prediction With Mixed Residue and Atom Graph Neural Network
Delaunay, A. P.; Fu, Y.; Begue, A.; McHardy, R.; Djermani, B. A.; Rooney, M.; Tovchigrechko, A.; Copoiu, L.; Skwark, M. J.; Lopez Carranza, N.; Lang, M.; Beguir, K.; Sahin, U.
10.1101/2022.11.23.517618 — bioinformatics — Posted on 2022-11-24
794 Optimization-Based Decoding of Imaging Spatial Transcriptomics Data
Bryan, J. P.; Binan, L.; McCann, C.; Eldar, Y. C.; Farhi, S. L.; Cleary, B.
10.1101/2022.11.22.517523 — bioinformatics — Posted on 2022-11-24
797 Adaptive nanopore sequencing for single cell characterization of cancer mutations and gene rearrangements
Grimes, S. M.; Kim, H. S.; Roy, S.; Sathe, A.; Ayala, C. I.; Almeida-Notestine, A. F.; Haebe, S.; Shree, T.; Levy, R.; Lau, B. T.; Ji, H. P.
10.1101/2022.11.22.517284 — genomics — Posted on 2022-11-24
798 Bursts in biosynthetic gene cluster transcription are accompanied by surges of natural compound production in the myxobacterium Sorangium sp.
Boldt, J.; Lukoseviciute, L.; Fu, C.; Steglich, M.; Bunk, B.; Junker, V.; Gollasch, A.; Trunkwalter, B.; Mohr, K.; Beckstette, M.; Wink, J.; Overmann, J.; Muller, R.; Nubel, U.
10.1101/2022.11.24.517636 — genomics — Posted on 2022-11-24
803 Drivers of mangrove vulnerability and resilience to tropical cyclones in the North Atlantic Basin
Amaral, C.; Poulter, B.; Lagomasino, D.; Fatoyinbo, T.; Taillie, P.; Lizcano, G.; Canty, S.; Herrera Silveira, J.; Teutli-Hernandez, C.; Cifuentes, M.; Charles, S.; Moreno, C. S.; Gonzalez-Trujillo, J.; Roman-Cuesta, R. M.
10.1101/2022.11.22.517275 — ecology — Posted on 2022-11-24
808 Transcriptome mining extends the host range of the Flaviviridae to non-bilaterians
Mifsud, J. C.; Costa, V. A.; Petrone, M. E.; Marzinelli, E. M.; Holmes, E. C.; Harvey, E.
10.1101/2022.11.24.517790 — microbiology — Posted on 2022-11-24
812 Boost the resilience of Protected Areas to shocks by reducing their dependency on tourism
Wilme, L.; Andrianambinina, F. O. D.; Schuurman, D.; Rakotoarijaona, M. A.; Razanajovy, C. N.; Ramparany, H. M.; Rafanoharana, S. C.; Rasamuel, H. A.; Faragher, K. D.; Waeber, P. O.
10.1101/2022.11.21.517412 — scientific communication and education — Posted on 2022-11-24
813 PlantServation: time-series phenotyping using machine learning revealed seasonal pigment fluctuation in diploid and polyploid Arabidopsis
Akiyama, R.; Goto, T.; Tameshige, T.; Sugisaka, J.; Kuroki, K.; Sun, J.; Akita, J.; Hatakeyama, M.; Kudoh, H.; Kenta, T.; Tonouchi, A.; Shimahara, Y.; Sese, J.; Kutsuna, N.; Shimizu-Inatsugi, R.; Shimizu, K. K.
10.1101/2022.11.21.517294 — plant biology — Posted on 2022-11-24
815 A single Verticillium dahliae effector determines pathogenicity on tomato by targeting auxin response factors
Li, J.; Faino, L.; Lorencini Fiorin, G.; Bashyal, S.; Schaveling, A.; van den Berg, G.; Seidl, M. F.; Thomma, B.
10.1101/2022.11.22.517554 — plant biology — Posted on 2022-11-24
816 Not all pathways are the same - unique adaptations to submerged environments emerge from comparative seagrass genomics
Bayer, P. E.; Fraser, M. W.; Martin, B. C.; Petereit, J.; Severn-Ellis, A. A.; Sinclair, E. A.; Batley, J.; Kendrick, G. A.; Edwards, D.
10.1101/2022.11.22.517588 — plant biology — Posted on 2022-11-24
818 ALMT-independent guard cell R-type anion currents
Jaslan, J.; Marten, I.; Jakobson, L.; Arjus, T.; Deeken, R.; Sarmiento, C.; De Angeli, A.; Bosche, M.; Kollist, H.; Hedrich, R.
10.1101/2022.11.24.517516 — plant biology — Posted on 2022-11-24
822 Assessment of Emerging Pretraining Strategies in Interpretable Multimodal Deep Learning for Cancer Prognostication
Azher, Z.; Suvarna, A.; Chen, J.-Q.; Zhang, Z.; Christensen, B.; Salas, L.; Vaickus, L.; Levy, J.
10.1101/2022.11.21.517440 — pathology — Posted on 2022-11-24
823 MuVEH and mitoMuVEH improve discovery of genetic variation from single cells.
Ransom, M. R.; Engel, K. L.; Stevens, B. M.; Jordan, C. T.; Gillen, A. E.
10.1101/2022.11.22.517553 — cancer biology — Posted on 2022-11-24
824 Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14
Miller, Z. A.; Jolivert, J. F.; Ma, R. Z.; Muthuswami, S.; Mueller, A.; McMahon, D. B.; Carey, R. M.; Lee, R. J.
10.1101/2022.11.22.517413 — cancer biology — Posted on 2022-11-24
827 Starfysh reveals heterogeneous spatial dynamics in the breast tumor microenvironment
He, S.; Jin, Y.; Nazaret, A.; Shi, L.; Chen, X.; Rampersaud, S.; Dhillon, B. S.; Valdez, I.; Friend, L. E.; Fan, J. L.; Park, C. Y.; Mintz, R.; Lao, Y.-H.; Carrera, D.; Fang, K. W.; Mehdi, K.; Rohde, M.; McFaline-Figueroa, J. L.; Blei, D.; Leong, K. W.; Rudensky, A. Y.; Plitas, G.; Azizi, E.
10.1101/2022.11.21.517420 — bioinformatics — Posted on 2022-11-24
828 HAPPY: A deep learning pipeline for mapping cell-to-tissue graphs across placenta histology whole slide images
Vanea, C.; Dzigurski, J.; Rukins, V.; Dodi, O.; Siigur, S.; Salumae, L.; Meir, K.; Parks, W. T.; Hochner-Celnikier, D.; Fraser, A.; Hochner, H.; Laisk, T.; Ernst, L. M.; Lindgren, C. M.; Nellaker, C.
10.1101/2022.11.21.517353 — bioinformatics — Posted on 2022-11-24
829 Fragment-Based Hit Discovery via Unsupervised Learning of Fragment-Protein Complexes
McCorkindale, W. J.; Ahel, I.; Barr, H.; Correy, G. J.; Fraser, J. S.; London, N.; Schuller, M.; Shurrush, K.; Lee, A. A.
10.1101/2022.11.21.517375 — bioinformatics — Posted on 2022-11-24
830 excluderanges: exclusion sets for T2T-CHM13, GRCm39, and other genome assemblies
Ogata, J. D.; Mu, W.; Davis, E. S.; Xue, B.; Harrell, J. C.; Sheffield, N. C.; Phanstiel, D. H.; Love, M. I.; Dozmorov, M. G.
10.1101/2022.11.21.517407 — bioinformatics — Posted on 2022-11-24
833 Rapid Real-time Squiggle Classification for Read Until Using RawMap
Sadasivan, H.; Wadden, J.; Goliya, K.; Wiens, J.; Dickson, R. P.; Blaauw, D.; Das, R.; Narayanasamy, S.
10.1101/2022.11.22.517599 — bioinformatics — Posted on 2022-11-24
838 Bioresorbable mesenchymal stem cell-loaded electrospun polymeric scaffold inhibits neointimal hyperplasia following arteriovenous fistula formation in a rat model of chronic kidney disease
Barcena, A. J. R.; Perez, J. V. D.; Bernardino, M.; Damasco, J. A.; Cortes, A.; Del Mundo, H.; San Valentin, E. M. D.; Klusman, C.; Canlas, G.; Heralde, F. M.; Avritscher, R.; Fowlkes, N.; Cheng, J.; Huang, S. Y.; Melancon, M. P.
10.1101/2022.11.21.517369 — bioengineering — Posted on 2022-11-24
839 IMPASTO: Multiplexed cyclic imaging without signal removal via self-supervised neural unmixing
Kim, H.; Bae, S.; Cho, J.; Nam, H.; Seo, J.; Han, S.; Yi, E.; Kim, E.; Yoon, Y.-G.; Chang, J.-B.
10.1101/2022.11.22.517463 — bioengineering — Posted on 2022-11-24
843 Exploring the association between Body Mass Index, Sex and Gene Expression in human colorectal epithelium
Lemler, L.; Donnelly, K.; Tomlinson, I.; Timofeeva, M.; Theodoratou, E.; Rozadilla, C. F.; Fernandez-Tajes, J.; Grimes, G.; Farrington, S.; Dunlop, M.
10.1101/2022.11.21.515057 — genomics — Posted on 2022-11-24
844 Characterization of caffeine response regulatory variants in vascular endothelial cells
Boye, C.; Kalita, C.; Findley, A. S.; Alazizi, A.; Wei, J.; Wen, X.; Pique-Regi, R.; Luca, F.
10.1101/2022.11.22.517533 — genomics — Posted on 2022-11-24
845 Neuron Navigator 1 Regulates Learning, Memory, and the Response to Multiple Potentially Addictive Drugs
Bagley, J. R.; Tan, Y.; Zu, W.; Cheng, Z.; Takeda, S.; Fang, Z.; Arslan, A.; Wang, M.; Guan, Y.; Jiang, L.; Jian, R.; Gu, F.; Parada, I.; Prince, D. A.; Jentsch, J. D.; Peltz, G.
10.1101/2022.11.21.517383 — genetics — Posted on 2022-11-24
846 Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria vector
Small, S. T.; Costantini, C.; Sagnon, N.; Guelbeogo, M. W.; Emrich, S. J.; Kern, A. D.; Fontaine, M. C.; Besansky, N. J.
10.1101/2022.11.21.517335 — evolutionary biology — Posted on 2022-11-24
848 Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus
Steenwyk, J. L.; Balamurugan, C.; Raja, H. A.; Goncalves, C.; Li, N.; Martin, F.; Berman, J.; Oberlies, N. H.; Gibbons, J. G.; Goldman, G. H.; Geiser, D. M.; Hibbett, D. S.; Rokas, A.
10.1101/2022.11.22.517304 — evolutionary biology — Posted on 2022-11-24
851 Neighbourhood species richness and drought-tolerance traits modulate tree growth and δ13C responses to drought
Schnabel, F.; Barry, K. E.; Eckhardt, S.; Guillemot, J.; Geilmann, H.; Kahl, A.; Moossen, H.; Bauhus, J.; Wirth, C.
10.1101/2022.11.22.517351 — ecology — Posted on 2022-11-24
855 Anti-integrin αvβ6 autoantibodies are a novel predictive biomarker in ulcerative colitis
Livanos, A. E.; Dunn, A.; Fischer, J.; Ungaro, R. C.; Turpin, W.; Lee, S.-H.; Rui, S.; Del Valle, D. M.; Julia, J. J.; Martinez-Delgado, G.; Riddle, M. S.; Murray, J. A.; Laird, R. M.; Torres, J.; Agrawal, M.; Magee, J. S.; Dervieux, T.; Gnjatic, S.; Sheppard, D.; Sands, B. E.; Porter, C. K.; Croitoru, K.; Petralia, F.; Colombel, J.-F.; Mehandru, S.
10.1101/2022.11.21.517399 — immunology — Posted on 2022-11-24
857 Proteome mapping of the human pancreatic islet microenvironment reveals endocrine-exocrine signaling sphere of influence
Gosline, S. J.; Velickovic, M.; Pino, J. C.; Day, L. Z.; Attah, I. K.; Swenson, A. C.; Danna, V.; Rodland, K. D.; Chen, J.; Mathews, C. E.; Cambell-Thompson, M.; Laskin, J.; Burnum-Johnson, K. E.; Zhu, Y.; Piehowski, P.
10.1101/2022.11.21.517388 — systems biology — Posted on 2022-11-24
863 Identifying Protein Haplotypes by Mass Spectrometry
Vasicek, J.; Skiadopoulou, D.; Kuznetsova, K. G.; Johansson, S.; Njolstad, P. R.; Bruckner, S.; Kall, L.; Vaudel, M.
10.1101/2022.11.21.517096 — bioinformatics — Posted on 2022-11-24
866 Tissue-specific overexpression of the double-stranded RNA transporter SID-1 limits lifespan in C. elegans
Camara, H.; Vergani-Junior, C. A.; Pinto, S.; Knittel, T. L.; Salgueiro, W. G.; Tonon-da-Silva, G.; Ramirez, J.; De-Souza, E. A.; Mori, M. A.
10.1101/2022.11.23.517635 — molecular biology — Posted on 2022-11-24
867 Structure and function of Plasmodium actin II in the parasite mosquito stages
Lopez, A. J.; Andreadaki, M.; Vahokoski, J.; Deligianni, E.; Calder, L. J.; Camerini, S.; Freitag, A.; Bergmann, U.; Rosenthal, P. B.; Siden-Kiamos, I.; Kursula, I.
10.1101/2022.11.22.517348 — biochemistry — Posted on 2022-11-24
868 The structural basis of the multi-step allosteric activation of Aurora B kinase
Sekulic, N.; Segura-Pena, D.; Hovet, O.; Gogoi, H.; Dawicki-McKenna, J. M.; Hansen Woien, S. M.; Carrer, M.; Black, B. E.; Cascella, M.
10.1101/2022.11.23.517677 — biochemistry — Posted on 2022-11-24
869 Biofilm characterization in the maize pathogen, Fusarium verticillioides
Peremore, C.; Wingfield, B.; Santana, Q.; Steenkamp, E.; Motaung, T. E.
10.1101/2022.11.18.517162 — microbiology — Posted on 2022-11-24
870 Feline Coronavirus Infection of Domestic Cats Causes Development of Cross-Reactive Antibodies to SARS-CoV-2 Receptor Binding Domain
Yamamoto, J. K.; Edison, L. K.; Rowe-Haas, D. K.; Takano, T.; Glior, C.; Crews, C. D.; Tuanyok, A.; Arukha, A. P.; Shiomitsu, S.; Walden, H. D. S.; Hohdatsu, T.; Tompkins, S. M.; Morris, J. G.; Sahay, B.; Kariyawasam, S.
10.1101/2022.11.23.517619 — microbiology — Posted on 2022-11-24
880 LUZP1 regulates the constriction velocity of the contractile ring during cytokinesis
Hyodo, T.; Asano-Inami, E.; Ito, S.; Sugiyama, M.; Nawa, A.; Rahman, M. L.; Hasan, M. N.; Mihara, Y.; Lam, V. Q.; Karnan, S.; Ota, A.; Tsuzuki, S.; Hamaguchi, M.; Hosokawa, Y.; Konishi, H.
10.1101/2022.07.04.498656 — cell biology — Posted on 2022-11-24
882 Development of two microbial source tracking markers for detection of wastewater-associated Escherichia coli isolates
Gomi, R.; Haramoto, E.; Wada, H.; Sugie, Y.; Ma, C.-Y.; Raya, S.; Malla, B.; Nishimura, F.; Tanaka, H.; Ihara, M.
10.1101/2022.08.23.505042 — microbiology — Posted on 2022-11-24
884 Genomic differentiation among European perch in the western Baltic Sea reflects colonization history and local adaptation
Skovrind, M.; Pacheco, G.; Christensen, E. A. F.; Gopalakrishnan, S.; Fietz, K.; Holm-Hansen, T. H.; Vieira, F. G.; Krag, M. A.; Carl, H.; Gilbert, M. T. P.; Olsen, M. T.; Moller, P. R.
10.1101/2022.11.23.516742 — molecular biology — Posted on 2022-11-24
885 Cerebral malaria is regulated by host mediated changes in Plasmodium gene expression
Cimperman, C.; Pena, M.; Gokcek, S.; Theall, B.; Patel, M.; Sharma, A.; Qi, C.; Sturdevant, D.; Miller, L.; Collins, P.; Pierce, S.; Akkaya, M.
10.1101/2022.11.23.517617 — microbiology — Posted on 2022-11-24
889 A model for Scc2p Stimulation of Cohesin's ATPase and its Inhibition by Acetylation of Smc3p
Boardman, K. M.; Xiang, S.; Chatterjee, F.; Mbonu, U.; Guacci, V. A.; Koshland, D.
10.1101/2022.11.23.517716 — genetics — Posted on 2022-11-23
890 Genetic mapping of craniofacial traits in the Mexican tetra reveals loci associated with bite differences between cave and surface fish
Powers, A. K.; Hyacinthe, C.; Riddle, M.; Kim, Y. K.; Amaismeier, A.; Thiel, K.; Martineau, B.; Ferrante, E.; Moran, R.; McGaugh, S.; Boggs, T.; Gross, J. B.; Tabin, C. E.
10.1101/2022.11.23.517717 — evolutionary biology — Posted on 2022-11-23
892 Physiological adaptation of sulfate reducing bacteria in syntrophic partnership with anaerobic methanotrophic archaea
Murali, R.; Yu, H.; Speth, D.; Wu, F.; Metcalfe, K. S.; Cremiere, A.; Laso-Perez, R.; Malmstrom, R.; Goudeau, D.; Woyke, T.; Hatzenpichler, R.; Chadwick, G.; Orphan, V. J.
10.1101/2022.11.23.517749 — microbiology — Posted on 2022-11-23
893 From cereus to anthrax and back again: The role of the PlcR regulator in the cross-over strain Bacillus cereus G9241
Manoharan, S.; Taylor-Joyce, G.; Brooker, T.; Hernandez-Rodriguez, C. S.; Hapeshi, A.; Baldwin, V.; Baillie, L.; Oyston, P.; Waterfield, N. R.
10.1101/2022.07.06.498675 — microbiology — Posted on 2022-11-23
894 Integrated Multi-omics Analyses of NFKB1 patients B cells points towards an up regula-tion of NF-κB network inhibitors
Camacho-Ordonez, N.; Ramirez, N.; Posadas-Cantera, S.; Caballero-Oyteza, A.; Fliegauf, M.; Zhao, F.; Guarini, M.; Gernedl, V.; Pecoroaro, M.; Warnatz, K.; Bock, C.; Ballestar, E.; Geiger, R.; Proietti, M.; Grimbacher, B.
10.1101/2022.11.22.517350 — immunology — Posted on 2022-11-23
898 Enzymatic assembly of small synthetic genes with repetitive elements
Nguyen, M. T. A.; Gobry, M. V.; Vallina, N. S.; Pothoulakis, G.; Andersen, E. S.
10.1101/2022.11.23.517630 — synthetic biology — Posted on 2022-11-23
902 The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate
Araya-Secchi, R.; Bugge, K.; Seiffert, P.; Petry, A.; Haxholm, G. W.; Lindorff-Larsen, K.; Pedersen, S. F.; Arleth, L.; Kragelund, B. B.
10.1101/2022.11.23.517650 — biophysics — Posted on 2022-11-23
905 Single Photon smFRET. I. Theory and Conceptual Basis
Saurabh, A.; Fazel, M.; Safar, M.; Sgouralis, I.; Presse, S.
10.1101/2022.07.20.500887 — biophysics — Posted on 2022-11-23
909 Mix-and-extrude using 3D printed nozzles for time-resolved membrane protein crystallography
Vakili, M.; Han, H.; Schmidt, C.; Wrona, A.; Kloos, M.; de Diego, I.; Dorner, K.; Valerio, J.; Round, E.; Lorenzen, K.; Schulz, J.
10.1101/2022.11.23.517685 — biochemistry — Posted on 2022-11-23
911 Zebrafish screen of high-confidence effector genes at insomnia GWAS loci implicates conserved regulators of sleep-wake behaviors
Zimmerman, A. J.; Doldur-Balli, F.; Keenan, B. T.; Shetty, Z. Y.; Palermo, J.; Chesi, A.; Sonti, S.; Pahl, M. C.; Brown, E. B.; Pippin, J. A.; Wells, A. D.; Mazzotti, D. R.; Veatch, O. J.; Krishnan, A.; Gehrman, P. R.; Keene, A. C.; Grant, S. F. A.; Pack, A. I.
10.1101/2022.10.05.511011 — genetics — Posted on 2022-11-23
915 Imaging with spatio-temporal modelling to characterize the dynamics of plant-pathogen lesions
Leclerc, M.; Jumel, S.; Hamelin, F. M.; Treilhaud, R.; Parisey, N.; Mammeri, Y.
10.1101/2022.01.13.476165 — ecology — Posted on 2022-11-23
916 A novel crosstalk between Nrf2 and Smad2/3 bridged by two nuanced Keap1 isoforms
Chen, F.; Xiao, M.; Lou, D.; Wang, Q.; Wufur, R.; Hu, S.; Zhang, Z.; Wang, Y.; Zhang, Y.
10.1101/2022.11.22.517594 — cell biology — Posted on 2022-11-23
917 CRISPRi in Deinococcus radiodurans
Misra, C. S.; Pandey, N.; Appukuttan, D.; Rath, D.
10.1101/2022.11.23.517625 — molecular biology — Posted on 2022-11-23
919 The influence of extrachromosomal elements in the anthrax cross-over strain Bacillus cereus G9241.
Taylor-Joyce, G.; Manoharan, S.; Brooker, T.; Hernandez-Rodriguez, C. S.; Baillie, L.; Oyston, P.; Hapeshi, A.; Waterfield, N. R.
10.1101/2022.07.13.499895 — microbiology — Posted on 2022-11-23
920 First Detection of Epizootic Haemorrhagic Disease virus in the European Union, Italy-2022.
Lorusso, A.; Cappai, S.; Loi, F.; Pinna, L.; Ruiu, A.; Puggioni, G.; Guercio, A.; Purpari, G.; Vicari, D.; Sghaier, S.; Zientara, S.; Spedicato, M.; Hammami, S.; Ben Hassine, T.; Portanti, O.; Breard, E.; Sailleau, C.; Ancora, M.; Di Sabatino, D.; Morelli, D.; Calistri, P.; Savini, G.
10.1101/2022.11.23.517495 — microbiology — Posted on 2022-11-23
922 Characterization of Genomic Diversity In Bacteriophages Infecting Rhodococcus
Garza, D. R.; Di Blasi, D.; Bruns, J. A.; Empson, B.; Ghannam, M.; Light, I.; Castillo, S.; Zorawik, M.; Garcia-Vedrenne, A. E.; Freise, A. C.
10.1101/2022.11.23.517428 — microbiology — Posted on 2022-11-23
923 A Bayesian model for human directional localization of broadband static sound sources
Barumerli, R.; Majdak, P.; Geronazzo, M.; Avanzini, F.; Meijer, D.; Baumgartner, R.
10.1101/2022.10.25.513770 — neuroscience — Posted on 2022-11-23
924 Homunculus Interruptus: A motor association area in the depth of the central sulcus
Jensen, M. A.; Huang, H.; Ojeda Valencia, G.; Klassen, B. T.; van den Boom, M. A.; Kaufmann, T. J.; Schalk, G.; Brunner, P.; Hermes, D.; Worrell, G. A.; Miller, K. J.
10.1101/2022.11.20.517292 — neuroscience — Posted on 2022-11-23
925 Supramodal Shape Representation in the Human Brain
Xu, Y.; Vignali, L.; Sigismondi, F.; Crepaldi, D.; Bottini, R.; Collignon, O.
10.1101/2022.11.22.517472 — neuroscience — Posted on 2022-11-23
927 Systematic characterization of brain cellular crosstalk signaling networks in Alzheimer's disease reveals a novel role for SEMA6D in TREM2-dependent microglial activation
D'Oliveira Albanus, R.; Finan, G.; Brase, L.; Chen, S.; Guo, Q.; Kannan, A.; Acquarone, M.; You, S.-F.; Novotny, B. C.; Ribeiro Pereira, P. M.; Morris, J. C.; McDade, E.; Cruchaga, C.; Chhatwal, J. P.; Dominantly Inherited Alzheimer Network (DIAN), ; Mace, E. E.; Benitez, B. A.; Piccio, L.; Sutherland, G. T.; Ma, Q.; Fu, H.; Karch, C. M.; Harari, O.; Kim, T.-W.
10.1101/2022.11.11.516215 — neuroscience — Posted on 2022-11-23
928 Competing neural representations of choice shape evidence accumulation in humans
Bond, K. A. M.; Rasero, J.; Madan, R.; Bahuguna, J.; Rubin, J.; Verstynen, T.
10.1101/2022.10.03.510668 — neuroscience — Posted on 2022-11-23
930 miRNome profiling of lung cancer metastases revealed a key role for miRNA-PD-L1 axis in the modulation of chemotherapy response
Cuttano, R.; Colangelo, T.; Guarize, J.; Dama, E.; Cocomazzi, M. P.; Mazzarelli, F.; Melocchi, V.; Palumbo, O.; Marino, E.; Belloni, E.; Montani, F.; Vecchi, M.; Barberis, M.; Graziano, P.; Pasquier, A.; Sanz-Ortega, J.; Montuenga, L. M.; Carbonelli, C.; Spaggiari, L.; Bianchi, F.
10.1101/2022.11.23.517634 — cancer biology — Posted on 2022-11-23
933 Structural and biochemical insights into heterotetramer formation between human oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Tariq, M.; Ikeya, T.; Togashi, N.; Fairall, L.; Bueno-Alejo, C.; Kamei, S.; Romartinez-Alonso, B.; Muro Campillo, M. A.; Hudson, A. J.; Ito, Y.; Schwabe, J. W.; Dominguez, C.; Tanaka, K.
10.1101/2022.10.10.511529 — biochemistry — Posted on 2022-11-23
937 Integrated transcriptome and proteomeanalysis in human brain organoids revealsposttranscriptional regulation of ribosomalgenes.
Sidhaye, J.; Trepte, P.; Sepke, N.; Novatchkova, M.; Schutzbier, M.; Duernberger, G.; Mechtler, K.; Knoblich, J. A.
10.1101/2022.10.07.511280 — developmental biology — Posted on 2022-11-23
938 CITED2 is a Conserved Regulator of the Uterine-Placental Interface
Kuna, M.; Dhakal, P.; Iqbal, K.; Dominguez, E. M.; Kent, L. N.; Muto, M.; Moreno-Irusta, A.; Kozai, K.; Varberg, K. M.; Okae, H.; Arima, T.; Sucov, H. M.; Soares, M. J.
10.1101/2022.06.15.496287 — developmental biology — Posted on 2022-11-23
940 Individual bat viromes reveal the co-infection, spillover and emergence risk of potential zoonotic viruses
Wang, J.; Pan, Y.; Yang, L.-f.; Yang, W.-h.; Luo, C.-m.; Wang, J.; Kuang, G.-p.; Wu, W.-c.; Gou, Q.-y.; Xin, G.-y.; Li, B.; Luo, H.-l.; Chen, Y.-q.; Shu, Y.-l.; Guo, D.; Gao, Z.-h.; Liang, G.; Li, J.; Holmes, E. C.; Feng, Y.; Shi, M.
10.1101/2022.11.23.517609 — microbiology — Posted on 2022-11-23
942 Engineered reporter phages for rapid detection of Escherichia coli, Klebsiella spp., and Enterococcus spp. in urine
Meile, S.; Du, J.; Staubli, S.; Grossmann, S.; Koliwer-Brandl, H.; Piffaretti, P.; Leitner, L.; Matter, C. I.; Baggenstos, J.; Hunold, L.; Milek, S.; Guebeli, C.; Kozomara-Hocke, M.; Neumeier, V.; Botteon, A.; Klumpp, J.; Marschall, J.; McCallin, S.; Zbinden, R.; Kessler, T. M.; Loessner, M. J.; Dunne, M.; Kilcher, S.
10.1101/2022.11.23.517494 — microbiology — Posted on 2022-11-23
943 Rasputin/G3BP mediates o-nyong-nyong virus subversion of antiviral immunity in Anopheles coluzzii
Cottis, S.; Blisnick, A.; Mitri, C.; Brito-Fravallo, E.; Matondo, M.; Failloux, A.-B.; Vernick, K. D.
10.1101/2022.11.23.517724 — microbiology — Posted on 2022-11-23
944 Fatty acid elongases 1-3 have distinct roles in mitochondrial function, growth and lipid homeostasis in Trypanosoma cruzi.
Pagura, L.; Dumoulin, P. C.; Ellis, C. C.; Estevao, I. L.; Mendes, M. T.; Almeida, I. C.; Burleigh, B. A.
10.1101/2022.11.22.517509 — microbiology — Posted on 2022-11-23
945 Functional promiscuity of small multidrug resistance transporters from Staphylococcus aureus, Pseudomonas aeruginosa, and Francisella tularensis
Spreacker, P. J.; Porter, C. J.; Wegrzynowicz, A.; Beeninga, W. F.; Demas, S. P.; Powers, E. N.; Henzler-Wildman, K. A.
10.1101/2022.11.22.517605 — microbiology — Posted on 2022-11-23
946 Apicomplexans predict thermal stress mortality in the Mediterranean coral Paramuricea clavata
Bonacolta, A. M.; Miravall, J.; Gomez-Gras, D.; Ledoux, J.-B.; Lopez-Sendino, P.; Garrabou, J.; Massana, R.; del Campo, J.
10.1101/2022.11.23.517658 — microbiology — Posted on 2022-11-23
947 Prophages regulate Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta
Natarajan, O.; Gibboney, S. L.; Young, M. N.; Lim, S. J.; Pluta, N.; Atkinson, C. G. F.; Leigh, B. A.; Liberti, A.; Kees, E. D.; Breitbart, M.; Gralnick, J. A.; Dishaw, L. J.
10.1101/2022.11.23.517592 — microbiology — Posted on 2022-11-23
949 Structure of LRRK1 and mechanisms of autoinhibition and activation
Reimer, J. M.; Dickey, A. M.; Lin, Y. X.; Abrisch, R. G.; Mathea, S.; Chatterjee, D.; Fay, E. J.; Daugherty, M. D.; Reck-Peterson, S. L.; Leschziner, A. E.
10.1101/2022.11.22.517582 — biochemistry — Posted on 2022-11-23
950 Monkeypox virus quadrivalent mRNA vaccine induces antibody responses and cellular immunity and protects mice against Vaccinia virus
Sang, Y.; Zhang, Z.; Liu, F.; Lu, H.; Yu, C.; Sun, H.; Long, J.; Cao, Y.; Mai, J.; Wang, X.; Fang, J.; Wang, Y.; Huang, W.; Yang, J.; Wang, S.
10.1101/2022.11.22.517500 — immunology — Posted on 2022-11-23
951 Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 Spike protein
Kuhn, C. C.; Basnet, N.; Bodakuntla, S.; Alvarez- Brecht, P.; Nichols, S.; Martinez-Sanchez, A.; Agostini, L.; Soh, Y.-M.; Takagi, J.; Biertumpfel, C.; Mizuno, N.
10.1101/2022.11.22.517574 — cell biology — Posted on 2022-11-23
952 Molecular and cellular similarities in the brain of SARS-CoV-2 and Alzheimer's disease individuals
Griggs, E.; Trageser, K.; Naughton, S.; Yang, E.-J.; Mathew, B.; Van Hyfte, G.; Hellmers, L.; Jette, N.; Estill, M.; Shen, L.; Fischer, T.; Pasinetti, G.
10.1101/2022.11.23.517706 — neuroscience — Posted on 2022-11-23
953 Organism-wide secretome mapping uncovers pathways of tissue crosstalk in exercise
Wei, W.; Riley, N. M.; Lyu, X.; Shen, X.; Guo, J.; Zhao, M.; Moya-Garzon, M. D.; Basu, H.; Tung, A.; Li, V. L.; Huang, W.; Svensson, K. J.; Snyder, M. P.; Bertozzi, C. R.; Long, J. Z.
10.1101/2022.11.21.517385 — systems biology — Posted on 2022-11-23
954 Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature
Zane, F.; Bouzid, H.; Besse, S.; Sosa Marmol, S.; Molina, J. L.; Cansell, C.; Aprahamian, F.; Durand, S.; Ayache, J.; Antoniewski, C.; Rera, M.
10.1101/2022.11.22.517330 — systems biology — Posted on 2022-11-23
956 Differential metabolic adaptations define responses of winner and loser oncogenic mutant stem cells in skin epidermis in vivo
Hemalatha, A.; Li, Z.; Tai, K.; Gonzalez, D. G.; Lathrop, E.; Gil, D.; Matte-Martone, C.; Ganesan, S.; Yun, S.; Gonzalez, L. E.; Skala, M. C.; Perry, R. J.; Greco, V.
10.1101/2022.11.21.517380 — cancer biology — Posted on 2022-11-23
960 Binding and sequestration of poison frog alkaloids by a plasma globulin
Alvarez-Buylla, A.; Moya Garzon, M. D.; Rangel, A. E.; Tapia, E. E.; Soh, H. T.; Coloma, L. A.; Long, J. Z.; O'Connell, L. A.
10.1101/2022.11.22.517437 — physiology — Posted on 2022-11-23
964 Recording animal-view videos of the natural world
Vasas, V.; Lowell, M. C.; Villa, J.; Jamison, Q. D.; Siegle, A. G.; Katta, P. K. R.; Bhagavathula, P.; Kevan, P. G.; Fulton, D.; Losin, N.; Kepplinger, D.; Salehian, S.; Forkner, R. E.; Hanley, D.
10.1101/2022.11.22.517269 — animal behavior and cognition — Posted on 2022-11-23
966 Cooperative breeding in a plural breeder: the vulturine guineafowl (Acryllium vulturinum)
Nyaguthii, B.; Dehnen, T.; Klarevas-IRby, J. A.; Papageorgiou, D.; Kosgey, J.; Farine, D. R.
10.1101/2022.11.23.517633 — animal behavior and cognition — Posted on 2022-11-23
967 IFNγ drives neuroinflammation and demyelination in a mouse model of multiple system atrophy
Gallups, N. J.; Childers, G. M.; Webster, J. M.; Yang, Y.-T.; Zane, A.; Mudium, N.; Manfredsson, F.; Kordower, J.; Harms, A. S.
10.1101/2022.11.22.517543 — neuroscience — Posted on 2022-11-23
968 Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer's disease
Pierson, S.; Fiock, K.; Wang, R.; Balasubramanian, N.; Khan, K.; Betters, R.; Lee, G.; Hefti, M. M.; Marcinkiewcz, C. A.
10.1101/2022.11.22.517403 — neuroscience — Posted on 2022-11-23
969 Predictive coordination of breathing during speaking and listening
Abbasi, O.; Kluger, D. S.; Chalas, N.; Steingraeber, N.; Meyer, L.; Gross, J.
10.1101/2022.11.23.517631 — neuroscience — Posted on 2022-11-23
972 Precision super-resolution cryo-correlative light and electron microscopy for rapid in situ structural analyses of optogenetically-positioned organelles
Redpath, G. M. I.; Rae, J. A.; Yao, Y.; Ruan, J.; Cagigas, M. L.; Whan, R.; Hardeman, E. C.; Gunning, P. W.; Ananthanarayanan, V.; Parton, R. G.; Ariotti, N.
10.1101/2022.11.22.516823 — cell biology — Posted on 2022-11-23
973 MAP4K4 regulates biomechanical forces at adherens junctions and focal adhesions to promote collective cell migration
Alberici Delsin, L. E.; Plutoni, C.; Clouvel, A.; Keil, S.; Marpeaux, L.; Elouassouli, L.; Khavari, A.; Ehrlicher, A.; Emery, G.
10.1101/2022.11.22.517545 — cell biology — Posted on 2022-11-23
974 Identifying Biomarkers of Retinal Pigment Epithelial Cell Stem Cell-derived RPE Cell Heterogeneity and Transplantation Efficacy
Farjood, F.; Manos, J. D.; Wang, Y.; Williams, A. L.; Zhao, C.; Borden, S.; Alam, N.; Prusky, G.; Temple, S.; Stern, J. H.; Boles, N. C.
10.1101/2022.11.22.517447 — cell biology — Posted on 2022-11-23
977 Enhancing Mitochondrial Functions by Optogenetic Clustering
Qiu, K.; Zou, W.; Tian, Z.; Huang, T.; Tsai, N.-P.; Zhang, K.; Diao, J.
10.1101/2022.11.22.517578 — cell biology — Posted on 2022-11-23
978 Golgi-IP, a novel tool for multimodal analysis of Golgi molecular content
Fasimoye, R.; Dong, W.; Nirujogi, R. S.; Rawat, E. S.; Iguchi, M.; Nyame, K.; Phung, T. K.; Bagnoli, E.; Prescott, A. R.; Alessi, D. R.; Abu-remaileh, M.
10.1101/2022.11.22.517583 — cell biology — Posted on 2022-11-23
979 Plasmodium exoerythrocytic parasites redirect trafficking of human proteins to the parasitophorous vacuole
Calla, J.; Mittal, N.; LaMonte, G.; Liffner, B.; Godinez-Macias, K.; Carolino, K.; Walker, G. T.; Zou, B. Y.; Paytas, E.; Guerra, L.; Tong-Rios, C.; Campo, B.; Vinetz, J. M.; Gamboa, D.; Raffatellu, M.; Absalon, S.; Winzeler, E.
10.1101/2022.11.22.517223 — cell biology — Posted on 2022-11-23
980 GenSLMs: Genome-scale language models reveal SARS-CoV-2 evolutionary dynamics.
Zvyagin, M. T.; Brace, A.; Hippe, K.; Deng, Y.; Zhang, B.; Orozco Bohorquez, C.; Clyde, A.; Kale, B.; Perez-Rivera, D.; Ma, H.; Mann, C. M.; Irvin, M.; Pauloski, J. G.; Ward, L.; Hayot, V.; Emani, M.; Foreman, S.; Xie, Z.; Lin, D.; Shukla, M.; Nie, W.; Romero, J.; Dallago, C.; Vahdat, A.; Xiao, C.; Gibbs, T.; Foster, I.; Davis, J. J.; Papka, M. E.; Brettin, T.; Anandkumar, A.; Vishwanath, V.; Ramanathan, A.
10.1101/2022.10.10.511571 — bioinformatics — Posted on 2022-11-23
982 Neuroblastoma-associated chromosomal aberrations drive cell identity loss in human neural crest via disruption of developmental regulators
Saldana-Guerrero, I. M.; Montano-Gutierrez, L. F.; Hafemeister, C.; Stavish, D.; Shaw, L. E.; Fetahu, I. S.; Wenninger-Weinzierl, A.; Sturtzel, C.; Souilhol, C.; Tarelli, S.; Shoeb, M. R.; Bernkopf, M.; Bozatzi, P.; Guarini, M.; Bozsaky, E.; Buri, M. C.; Putz, E. M.; Andrews, P. W.; Barbaric, I.; Bryant, H. E.; Distel, M.; Taschner-Mandl, S.; Farlik, M.; Tsakiridis, A.; Halbritter, F.
10.1101/2022.11.21.515753 — cancer biology — Posted on 2022-11-23
984 A human mitofusin 2 mutation causes mitophagic cardiomyopathy
Franco, A.; Li, J.; Kelly, D. P.; Hershberger, R. E.; Marian, A. J.; Lewis, R. M.; Song, M.; Dang, X.; Schmidt, A. D.; Mathyer, M. E.; Strong, C. d. G.; Dorn, G. W.
10.1101/2022.11.22.517462 — developmental biology — Posted on 2022-11-23
985 An intact S-layer is advantageous to Clostridioides difficile within the host.
Ormsby, M. J.; Vaz, F.; Kirk, J. A.; Barwinska-Sendra, A.; Hallam, J. C.; Lanzoni-Mangutchi, P.; Cole, J.; Chaudhuri, R. R.; Salgado, P. S.; Fagan, R. P.; Douce, G.
10.1101/2022.11.22.517470 — microbiology — Posted on 2022-11-23
986 dsRNA-induced immunity targets plasmodesmata and is suppressed by viral movement proteins
Huang, C.; Sede, A. R.; Elvira-Gonzalez, L.; Yan, Y.; Rodriguez, M.; Mutterer, J.; Boutant, E.; Shan, L.; Heinlein, M.
10.1101/2022.11.21.517408 — plant biology — Posted on 2022-11-23
988 Investigating the potential of packed cell volume for deducing hemoglobin: Cholistani camels in perspective
Farooq, U.; Idris, M.; Sajjad, N.; Lashari, M. H.; Ahmad, S.; Rehman, Z. U.; Rashid, H.; Mahmood, A.; Hameed, S.
10.1101/2022.11.15.516630 — physiology — Posted on 2022-11-23
990 A ubiquitous spectrolaminar motif of local field potential power across the primate cortex
Mendoza-Halliday, D.; Major, A. J.; Lee, N.; Lichtenfeld, M.; Carlson, B.; Mitchell, B.; Meng, P. D.; Xiong, Y.; Westerberg, J. A.; Maier, A.; Desimone, R.; Miller, E. K.; Bastos, A. M.
10.1101/2022.09.30.510398 — neuroscience — Posted on 2022-11-22
993 Design principles of caveolins across metazoa and beyond
Han, B.; Wilson, L. F. L.; Gulsevin, A.; Meiler, J.; Karakas, E.; Kenworthy, A. K.
10.1101/2022.11.15.516482 — biophysics — Posted on 2022-11-22
998 Structural and biochemical insights into heterotetramer formation between human oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Tariq, M.; Ikeya, T.; Togashi, N.; Fairall, L.; Bueno-Alejo, C.; Kamei, S.; Romartinez-Alonso, B.; Muro Campillo, M. A.; Hudson, A. J.; Ito, Y.; Schwabe, J. W.; Dominguez, C.; Tanaka, K.
10.1101/2022.10.10.511529 — biochemistry — Posted on 2022-11-22
1000 The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
Rozowsky, J.; Drenkow, J.; Yang, Y.; Gursoy, G.; Galeev, T.; Borsari, B.; Epstein, C.; Xiong, K.; Xu, J.; Gao, J.; Yu, K.; Berthel, A.; Chen, Z.; Navarro, F.; Liu, J.; Sun, M.; Wright, J.; Chang, J.; Cameron, C.; Shoresh, N.; Gaskell, E.; Adrian, J.; Aganezov, S.; Balderrama-Gutierrez, G.; Banskota, S.; Corona, G.; Chee, S.; Chhetri, S.; Martins, G.; Danyko, C.; Davis, C.; Farid, D.; Farrell, N.; Gabdank, I.; Gofin, Y.; Gorkin, D.; Gu, M.; Hecht, V.; Hitz, B.; Issner, R.; Kirsche, M.; Kong, X.; Lam, B.; Li, S.; Li, B.; Li, T.; Li, X.; Lin, K.; Luo, R.; Mackiewicz, M.; Moore, J.; Mudge, J.; Nel
10.1101/2021.04.26.441442 — genomics — Posted on 2022-11-22
1003 A novel RHH family transcription factor aCcr1 and its viral homologs dictate cell cycle progression in archaea
Yang, Y.; Liu, J.; Fu, X.; Zhou, F.; Zhang, S.; Zhang, X.; Huang, Q.; Krupovic, M.; She, Q.; Ni, J.; Shen, Y.
10.1101/2022.07.07.499082 — microbiology — Posted on 2022-11-22
1006 Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons
Venkatesan, S.; Chen, T.; Liu, Y.; Turner, E. E.; Tripathy, S.; Lambe, E. K.
10.1101/2022.06.20.496737 — neuroscience — Posted on 2022-11-22
1007 Tracking the neural dynamics of semantic composition through negation
Zuanazzi, A.; Ripolles, P.; Lin, W. M.; Gwilliams, L.; King, J.-R.; Poeppel, D.
10.1101/2022.10.14.512299 — neuroscience — Posted on 2022-11-22
1008 CHRNA5 links chandelier cells to protection against amyloid pathology in human aging and Alzheimer's Disease
Rybnicek, J.; Chen, Y.; Milic, M.; McLaurin, J.; De Jager, P.; Schneider, J. A.; Wang, Y.; Bennett, D. A.; Tripathy, S.; Felsky, D.; Lambe, E. K.
10.1101/2022.05.03.490491 — neuroscience — Posted on 2022-11-22
1012 Mechanism of RanGTP priming the release of H2A-H2B from Kap114 and Importin-9
Jiou, J.; Shaffer, J. M.; Bernardes, N. E.; Tripathi, K.; Fung, H. Y. J.; . Olaluwoye, O. S.; Kikumoto Dias, J.; Chook, Y. M.; D'Arcy, S.
10.1101/2022.11.22.517512 — biochemistry — Posted on 2022-11-22
1015 AKT1-FOXO4 AXIS RECIPROACLLY REGULATES HEMOCHORIAL PLACENTATION
Kozai, K.; Moreno Irusta, A.; Iqbal, K.; Winchester, M.-L.; Scott, R. L.; Simon, M. E.; Muto, M.; Parrish, M. R.; Soares, M. J.
10.1101/2022.06.15.496110 — developmental biology — Posted on 2022-11-22
1016 Notch engagement by Jag1 nanoscale clusters indicates a force-independent mode of activation
Smyrlaki, I.; Fördös, F.; Rocamonde Lago, I.; Wang, Y.; Lentini, A.; Luca, V. C.; Reinius, B.; Teixeira, A. I.; Högberg, B.
10.1101/2022.11.22.517517 — cell biology — Posted on 2022-11-22
1017 Chronic Glucocorticoid Stress Reveals Increased Energy Expenditure and Accelerated Aging as Cellular Features of Allostatic Load
Bobba-Alves, N.; Sturm, G.; Lin, J.; Ware, S. A.; Karan, K. R.; Monzel, A. S.; Bris, C.; Procaccio, V.; Lenaers, G.; Higgins-Chen, A.; Levine, M.; Horvath, S.; Santhanam, B. S.; Kaufman, B. A.; Hirano, M.; Epel, E. S.; Picard, M.
10.1101/2022.02.22.481548 — cell biology — Posted on 2022-11-22
1021 Molecular Neurobiology of Loss
Smail, M. A.; Smith, B. L.; Shukla, R.; Alganem, K.; Eby, H. M.; Bollinger, J. L.; Parikh, R. K.; Chambers, J. B.; Reigle, J. K.; Moloney, R. D.; Nawreen, N.; Wohleb, E. S.; Pantazopoulos, H.; McCullumsmith, R. E.; Herman, J. P.
10.1101/2022.07.13.499899 — neuroscience — Posted on 2022-11-22
1022 A tRNA Modification-based strategy for Identifying amiNo acid Overproducers (AMINO)
Guo, H.; Ma, X.; Wang, N.; Ding, T.; Zheng, B.; Guo, L.; Huang, C.; Zhang, W.; Sun, L.; huo, y.
10.1101/2022.11.21.517450 — synthetic biology — Posted on 2022-11-22
1023 Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria
Dolcemascolo, R.; Heras-Herandez, M.; Goiriz, L.; Montagud-Martinez, R.; Requena-Menendez, A.; Marquez-Costa, R.; Ruiz, R.; Perez-Rafols, A.; Higuera-Rodriguez, R. A.; Perez-Ropero, G.; Vranken, W. F.; Martelli, T.; Kaiser, W.; Buijs, J.; Rodrigo, G.
10.1101/2022.11.22.516435 — synthetic biology — Posted on 2022-11-22
1025 MMP2 loss leads to defective parturition and severe dystocia in mice
Kalev-Altman, R.; Levy, T.; Shpigel, N. Y.; Monsonego-Ornan, E.; Sela-Donenfeld, D.
10.1101/2022.11.22.517326 — physiology — Posted on 2022-11-22
1026 Comprehensive glycoprofiling of oral tumours associates N-glycosylation with lymph node metastasis and patient survival
Moretto Carnielli, C.; Melo de Lima Morais, T.; Malta de Sa Patroni, F.; Prado Ribeiro, A. C.; Brandao, T. B.; Sobroza, E.; Luongo Matos, L.; Kowalski, L. P.; Paes Leme, A.; Kawahara, R.; Thaysen-Andersen, M.
10.1101/2022.11.21.517331 — cancer biology — Posted on 2022-11-22
1028 CRISPR/Cas9-based repeat depletion for the high-throughput genotyping of complex plant genomes
Rossato, M.; Marcolungo, L.; De Antoni, L.; Lopatriello, G.; Bellucci, E.; Cortinovis, G.; Frascarelli, G.; Nanni, L.; Bitocchi, E.; Di Vittori, V.; Vincenzi, L.; Lucchini, F.; Bett, K.; Ramsay, L.; Konkin, D. J.; Delledonne, M.; Papa, R.
10.1101/2022.11.22.517518 — genomics — Posted on 2022-11-22
1029 Uncharacterized protein c17orf80: a novel interactor of human mitochondrial nucleoids
Potter, A.; Hangas, A.; Goffart, S.; Huynen, M. A.; Cabrera-Orefice, A.; Spelbrink, J. N.
10.1101/2022.11.21.516320 — molecular biology — Posted on 2022-11-22
1032 Massively parallel single-cell sequencing of genetic loci in diverse microbial populations
Lan, F.; Saba, J.; Ross, T. D.; Zhou, Z.; Krauska, K.; Anantharaman, K.; Landick, R.; Venturelli, O. S.
10.1101/2022.11.21.517444 — microbiology — Posted on 2022-11-22
1033 Factors governing attachment of Rhizobium leguminosarum to legume roots
Parsons, J.; Cocker, C.; East, A.; Wheatley, R.; Ramachandran, V.; Kaschani, F.; Kaiser, M.; Poole, P.
10.1101/2022.11.21.517457 — microbiology — Posted on 2022-11-22
1036 Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation
Zein, L.; Grossmann, J.; Swoboda, H.; Borgel, C.; Wilke, B.; Awe, S.; Nist, A.; Stiewe, T.; Stehling, O.; Freibert, S.-A.; Adhikary, T.; Chung, H.-R.
10.1101/2022.11.22.516855 — immunology — Posted on 2022-11-22
1037 Reducing brain kynurenic acid synthesis precludes kynurenine-induced sleep disturbances
Rentschler, K. M.; Milosavljevic, S.; Baratta, A. M.; Wright, C. J.; Piroli, M. V.; Wagner, N. T.; Pocivavsek, A.
10.1101/2022.11.21.517377 — neuroscience — Posted on 2022-11-22
1039 High-fat diet feeding triggers a regenerative response in the adult zebrafish brain
Azbazdar, Y.; Poyraz, Y. K.; Ozalp, O.; Nazli, D.; Ipekgil, D.; Cucun, G.; Ozhan, G.
10.1101/2022.11.22.517521 — neuroscience — Posted on 2022-11-22
1043 Influence of pump laser fluence on ultrafast structural changes in myoglobin
Barends, T. R. M.; Bhattacharyya, S.; Gorel, A.; Schiro, G.; Bacellar, C.; Cirelli, C.; Colletier, J.-P.; Foucar, L.; Gruenbein, M. L.; Hartmann, E.; Hilpert, M.; Johnson, P.; Kloos, M.; Knopp, G.; Marekha, B.; Nass, K.; Ozerov, D.; Stricker, M.; Weik, M.; Doak, B.; Shoeman, R.; Milne, C.; Huix-Rotllant, M.; Cammarata, M.; Schlichting, I.
10.1101/2022.11.22.517513 — biophysics — Posted on 2022-11-22
1045 O-GlcNAcylation promotes YTHDF1 cytosolic localization and colorectal cancer tumorigenesis
Li, J.; Ahmad, M.; Sang, L.; Zhan, Y.; Wang, Y.; Yan, Y.; Liu, Y.; Mi, W.; Lu, M.; Dai, Y.; Zhang, R.; Dong, M.-Q.; Yang, Y.; Wang, X.; Sun, J.; Li, J.
10.1101/2022.11.21.517456 — biochemistry — Posted on 2022-11-22
1046 AlphaFold predictions: great hypotheses but no match for experiment
Terwilliger, T. C.; Leibschner, D. L.; Croll, T.; Williams, C. J.; McCoy, A. J.; Poon, B. K.; Afonine, P.; Oeffner, R. D.; Richardson, J. S.; Read, R. J.; Adams, P. D.
10.1101/2022.11.21.517405 — biochemistry — Posted on 2022-11-22
1047 Expanding the Huntingtons disease research toolbox; validated huntingtin subdomain constructs for biochemical and structural investigation of the huntingtin protein
Alteen, M. G.; Deme, J. C.; Alvarez, C. P.; Loppnau, P.; Hutchinson, A.; Seitova, A.; Chandrasekaran, R.; Silva Ramos, E.; Secker, C.; Alqazzaz, M.; Wanker, E. E.; Lea, S. M.; Arrowsmith, C. H.; Harding, R. J.
10.1101/2022.11.21.516512 — biochemistry — Posted on 2022-11-22
1050 Environmental and genetic drivers of population differences in SARS-CoV-2 immune responses
Aquino, Y.; Bisiaux, A.; Li, Z.; O'Neill, M.; Mendoza-Revilla, J.; Merkling, S. H.; Kerner, G.; Hasan, M.; Libri, V.; Bondet, V.; Smith, N.; de Cevins, C.; Menager, M. M.; Luca, F.; Pique-Regi, R.; Barba-Spaeth, G.; Pietropaoli, S.; Schwartz, O.; Leroux-Roels, G.; Lee, C.-K.; Leung, K.; Wu, J. T. K.; Peiris, J. S. M.; Bruzzone, R.; Abel, L.; Casanova, J.-L.; Valkenburg, S. A.; Duffy, D. A.; Patin, E.; Rotival, M.; Quintana-Murci, L.
10.1101/2022.11.22.517073 — genomics — Posted on 2022-11-22
1052 EEG and pupillometric signatures of working memory overload
Kosachenko, A. I.; Kasanov, D.; Kotyusov, A. I.; Pavlov, Y. G.
10.1101/2022.11.21.517347 — neuroscience — Posted on 2022-11-22
1053 A replication study on key neurodevelopmental pathways affected by valproate treatment ofneural precursor cells
sukumaran, s.; M, S.; Iyer, S.; Banerjee, A.; Purushottam, M.; Jain, S.; Viswanath, B.; Sud, R.
10.1101/2022.11.21.517445 — neuroscience — Posted on 2022-11-22
1055 Supramodal Shape Representation in the Human Brain
Xu, Y.; Vignali, L.; Sigismondi, F.; Crepaldi, D.; Bottini, R.; Collignon, O.
10.1101/2022.11.22.517472 — neuroscience — Posted on 2022-11-22
1057 Isolated catatonia-like executive dysfunction in micewith forebrain-specific loss of myelin integrity
Arinrad, S.; Depp, C.; Siems, S. B.; Sasmita, A. O.; Eichel, M. A.; Ronnenberg, A.; Hammerschmidt, K.; Lueders, K. A.; Werner, H. B.; Ehrenreich, H.; Nave, K.-A.
10.1101/2022.11.21.517320 — neuroscience — Posted on 2022-11-22
1060 Magnetic resonance imaging datasets with anatomical fiducials for quality control and registration
Taha, A.; Gilmore, G.; Abbass, M.; Kai, J.; Kuehn, T.; Demarco, J.; Gupta, G.; Zajner, C.; Cao, D.; Chevalier, R.; Ahmed, A.; Hadi, A.; Karat, B.; Stanley, O. W.; Park, P.; Ferko, K. M.; Hemachandra, D.; Vassallo, R.; Jach, M.; Thurairajah, A.; Wong, S.; Ogunsanya, F.; Tenorio, M. C.; Khan, A. R.; Lau, J. C.
10.1101/2022.11.21.516173 — neuroscience — Posted on 2022-11-22
1061 Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment
Kolb, J.; John, N.; Kim, K.; Möckel, C.; Rosso, G.; Möllmert, S.; Kurbel, V.; Parmar, A.; Sharma, G.; Beck, T.; Müller, P.; Schlüssler, R.; Frischknecht, R.; Wehner, A.; Krombholz, N.; Steigenberger, B.; Blümcke, I.; Singh, K.; Guck, J.; Kobow, K.; Wehner, D.
10.1101/2022.11.21.517128 — neuroscience — Posted on 2022-11-22
1065 Stress-associated purinergic receptors code for fatal suicidality in the hippocampal-hypothalamic-prefrontal circuit
Zhang, L.; Verwer, R. W. H.; van Heerikhuize, J.; Balesar, R.; Correa-da-Silva, F.; Slabe, Z.; Lucassen, P. J.; Swaab, D. F.
10.1101/2022.11.22.516142 — neuroscience — Posted on 2022-11-22
1068 Prior movement of one arm facilitates motor adaptation in the other
Gippert, M.; Leupold, S.; Heed, T.; Howard, I. S.; Villringer, A.; Nikulin, V.; Sehm, B.
10.1101/2022.11.22.517483 — neuroscience — Posted on 2022-11-22
1069 Efficacy of Non-invasive Brain Stimulation on Vision: A Systematic Review and Meta-analysis
Bello, U. M.; Wang, J.; Park, A. S.; Tan, K. W.; Cheung, B. W.; Thompson, B. B.; Cheong, A. M.
10.1101/2022.11.22.517490 — neuroscience — Posted on 2022-11-22
1070 Cross-movie prediction of individualized functional topography
Jiahui, G.; Feilong, M.; Nastase, S. A.; Haxby, J. V.; Gobbini, M. I.
10.1101/2022.11.21.517253 — neuroscience — Posted on 2022-11-22
1071 Mapping neuroinflammation in vivo with diffusion-MRI in rats given a systemic lipopolysaccharide challenge
Kim, E.; Carreira Figueiredo, I.; Simmons, C.; Randall, K.; Rojo Gonzalez, L.; Wood, T. C.; Ranieri, B.; Sureda-Gibert, P.; Pariante, C.; NIMA Consortium, ; Pasternak, O.; Dell'Acqua, F.; Turkheimer, F. E.; Cash, D.
10.1101/2022.11.22.517484 — neuroscience — Posted on 2022-11-22
1074 Mitochondrial defects leading to arrested spermatogenesis and ferroptosis in a mouse model of Leigh Syndrome
Radaelli, E.; Assenmacher, C.-A.; Banerjee, E.; Manero, F.; Khiati, S.; Girona, A.; Lopez-Lluch, G.; Navas, P.; Spinazzi, M.
10.1101/2022.11.22.517461 — cell biology — Posted on 2022-11-22
1077 SMARCB1 loss creates patient-specific MYC topologies that drive malignant rhabdoid tumor growth
Liu, N. Q.; Paassen, I.; Custers, L.; Teunissen, H.; Ayyildiz, D.; He, J.; Hoving, E. W.; de Wit, E.; Drost, J.
10.1101/2022.11.21.516939 — cancer biology — Posted on 2022-11-22
1079 Plastid Genome Assembly Using Long-read Data (ptGAUL)
Zhou, W.; Armijos, C.; Lee, C.; Lu, R.; Wang, J.; Ruhlman, T.; Jansen, R.; Jones, A.; Jones, C.
10.1101/2022.11.19.517194 — bioinformatics — Posted on 2022-11-22
1080 SUMO - In Silico Sequence Assessment Using Multiple Optimization Parameters
Evers, A.; Malhotra, S.; Bolick, W.-G.; Najafian, A.; Borisovska, M.; Warszawski, S.; Fomekong Nanfack, Y.; Kuhn, D.; Rippmann, F.; Crespo, A.; Sood, V.
10.1101/2022.11.19.517175 — bioinformatics — Posted on 2022-11-22
1081 Computational investigations in inhibition of alcohol/aldehyde dehydrogenase in lignocellulosic hydrolysates
Kumar, K.; Mohammad, A. S.; Pragati, ; Chandane, P.; Yadav, S.; Kori, M.; Ram, A. S.; Barbora, L.; Moholkar, V. S.
10.1101/2022.11.19.517192 — bioinformatics — Posted on 2022-11-22
1085 The binding sites of E2F transcription factor in Drosophila metabolic genes are functionally distinct
Zappia, M. P.; Kwon, Y.-J.; Westacott, A.; Liseth, I.; Lee, H. M.; Islam, A.; Kim, J.; Frolov, M. V.
10.1101/2022.11.22.517506 — developmental biology — Posted on 2022-11-22
1087 The Lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope accessibility
Wallace, M.; Fedorchak, G. R.; Agrawal, R.; Gilbert, R. M.; Patel, J.; Park, S.; Paszek, M.; Lammerding, J.
10.1101/2022.11.22.517482 — cell biology — Posted on 2022-11-22
1089 Feedback brings scene information to the representation of occluded image regions in area V1 of monkeys and humans
Papale, P.; Wang, F.; Morgan, A. T.; Chen, X.; Gilhuis, A.; Petro, L. S.; Muckli, L.; Roelfsema, P. R.; Self, M. W.
10.1101/2022.11.21.517305 — neuroscience — Posted on 2022-11-22
1093 BEHAVIOURAL VOLUNTARY AND SOCIAL BIOASSAYS ENABLING IDENTIFICATION OF COMPLEX AND SEX DEPENDENT PAIN- (-RELATED) PHENOTYPES IN RATS WITH BONE CANCER
Segelcke, D.; Linnemann, J.; Pradier, B.; Kronenberg, D.; Stange, R.; Richter, H.; Goerlich, D.; Baldini, N.; Di Pompo, G.; Verri, W. A.; Avent, S.; Pogatzki-Zahn, E. M.
10.1101/2022.11.19.517016 — cancer biology — Posted on 2022-11-22
1096 OpenFold: Retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization
Ahdritz, G.; Bouatta, N.; Kadyan, S.; Xia, Q.; Gerecke, W.; O'Donnell, T. J.; Berenberg, D.; Fisk, I.; Zanichelli, N.; Zhang, B.; Nowaczynski, A.; Wang, B.; Stepniewska-Dziubinska, M. M.; Zhang, S.; Ojewole, A.; Guney, M. E.; Biderman, S.; Watkins, A. M.; Ra, S.; Lorenzo, P. R.; Nivon, L.; Weitzner, B.; Ban, Y.-E. A.; Sorger, P. K.; Mostaque, E.; Zhang, Z.; Bonneau, R.; AlQuraishi, M.
10.1101/2022.11.20.517210 — bioinformatics — Posted on 2022-11-22
1099 A Framework for Designing Efficient Deep Learning-Based Genomic Basecallers
Singh, G.; Alser, M.; Khodamoradi, A.; Denolf, K.; Firtina, C.; Cavlak, M. B.; Corporaal, H.; Mutlu, O.
10.1101/2022.11.20.517297 — genomics — Posted on 2022-11-22
1105 In-depth characterization of the Syrian hamster as translational model for COVID-19 in humans
Castellan, M.; Zamperin, G.; Franzoni, G.; Foiani, G.; Zorzan, M.; Drzewniokova, P.; Mancin, M.; Brian, I.; Bortolami, A.; Pagliari, M.; Oggiano, A.; Vascellari, M.; Panzarin, V.; Crovella, S.; Monne, I.; Terregino, C.; De Benedictis, P.; Leopardi, S.
10.1101/2022.11.22.517339 — immunology — Posted on 2022-11-22
1106 Nirmatrelvir treatment blunts the development of antiviral adaptive immune responses in SARS-CoV-2 infected mice
Fumagalli, V.; Di Lucia, P.; Rava, M.; Marotta, D.; Bono, E.; Grassi, S.; Donnici, L.; Cannalire, R.; Stefanelli, I.; Ferraro, A.; Esposito, F.; Pariani, E.; Inverso, D.; Montesano, C.; Delbue, S.; Tramontano, E.; De Francesco, R.; Summa, V.; Guidotti, L.; Iannacone, M.
10.1101/2022.11.22.517465 — immunology — Posted on 2022-11-22
1107 Instantaneous antidepressant effect of lateral habenula deep brain stimulation in rats studied with functional magnetic resonance imaging
Li, G.; Bo, B.; Wang, P.; Qian, P.; Li, M.; Li, Y.; Tong, C.; Zhang, K.; Zhang, B.; Jiang, T.; Liang, Z.; Duan, X.
10.1101/2022.11.20.517264 — neuroscience — Posted on 2022-11-22
1112 Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England
Yu, Q.; Ascensao, J. A.; Okada, T.; The COVID-19 Genomics UK (COG-UK) consortium, ; Boyd, O.; Volz, E.; Hallatschek, O.
10.1101/2022.11.21.517390 — evolutionary biology — Posted on 2022-11-22
1115 Epigenetic variations are landmarks of freshwater adaptation in threespine sticklebacks
Golden, A.; Starshin, A.; Mazur, A.; Mugue, N.; Kaplun, D.; Artemov, A.; Khrameeva, E.; Prokhortchouk, E.
10.1101/2022.08.22.504457 — evolutionary biology — Posted on 2022-11-22
1116 Stress deceleration theory - chronic adolescent stress exposure results in decelerated neurobehavioral maturation
Jadhav, K.; Hoffman, A.; Burgisser, M.; Rosetti, C.; Aeschlimann, L.; Lupica, C. R.; Boutrel, B.
10.1101/2021.11.21.469381 — neuroscience — Posted on 2022-11-22
1118 Multi-omics analysis reveals the molecular response to heat stress in a "red tide" dinoflagellate
Dougan, K. E.; Deng, Z.-L.; Woehlbrand, L.; Reuse, C.; Bunk, B.; Chen, Y.; Hartlich, J.; Hiller, K.; John, U.; Kalvelage, J.; Mansky, J.; Neumann-Schaal, M.; Overmann, J.; Petersen, J.; Sanchez-Garcia, S.; Schmidt-Hohagen, K.; Shah, S.; Sproer, C.; Sztajer, H.; Wang, H.; Bhattacharya, D.; Rabus, R.; Jahn, D.; Chan, C. X.; Wagner-Doebler, I.
10.1101/2022.07.25.501386 — genomics — Posted on 2022-11-22
1119 HSV-1 infection induces a downstream shift of promoter-proximal pausing for most host genes
Weiss, E.; Hennig, T.; Grassl, P.; Djakovic, L.; Whisnant, A. W.; Juerges, C. S.; Koller, F.; Kluge, M.; Erhard, F.; Doelken, L.; Friedel, C. C.
10.1101/2022.09.28.509911 — molecular biology — Posted on 2022-11-22
1120 Novel mRNA vaccines encoding Monkeypox virus M1R and A35R protect mice from a lethal virus challenge
Hou, F.; Zhang, Y.; Liu, X.; Murad, Y.; Xu, J.; Yu, Z.; Hua, X.; Song, Y.; Ding, J.; Huang, H.; Zhao, R.; Jia, W.; Yang, X.
10.1101/2022.11.19.517190 — immunology — Posted on 2022-11-22
1121 Disentangling the role of NAc D1 and D2 cells in hedonic eating
Guillaumin, M. C. C.; Viskaitis, P.; Bracey, E.; Burdakov, D.; Peleg-Raibstein, D.
10.1101/2022.10.29.514339 — neuroscience — Posted on 2022-11-22
1122 Prioritization of abiotic and biotic plant stress responses through ABI1 phosphatase and CPK5 calcium-dependent protein kinase switch
Seybold, H.; Bortlik, J.; Jiang, X.; Liese, A.; Conrads, B.; Hoehenwarter, W.; Matschi, S.; Romeis, T.
10.1101/839662 — plant biology — Posted on 2022-11-22
1123 Ultrasound treatment inhibits SARS-CoV-2 in vitro infectivity
Veras, F. P.; Martins, R.; Arruda, E.; Cunha, F. Q.; Bruno, O. M.
10.1101/2022.11.21.517338 — biophysics — Posted on 2022-11-22
1125 Predicting the Key Regulators of Cell Identity in Human Adult Pancreas
Vanheer, L.; Fantuzzi, F.; To, S. K.; Schiavo, A. A.; Van Haele, M.; Haesen, T.; Yi, X.; Janiszewski, A.; Chappell, J.; Rihoux, A.; Sawatani, T.; Roskams, T.; Pattou, F.; Kerr-Conte, J.; Cnop, M.; Pasque, V.
10.1101/2020.09.23.310094 — bioinformatics — Posted on 2022-11-22
1127 YgfB increases β-lactam resistance in Pseudomonas aeruginosa by counteracting AlpA-mediated ampDh3 expression
Eggers, O.; Renschler, F.; Michalek, L. A.; Wackler, N.; Walter, E.; Smollich, F.; Klein, K.; Sonnabend, M.; Egle, V.; Angelov, A.; Engesser, C.; Borisova, M.; Mayer, C.; Schuetz, M.; Bohn, E.
10.1101/2022.07.05.498809 — microbiology — Posted on 2022-11-22
1128 PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven adaptive resistance
Wong, C. W.; Evangelou, C.; Sefton, K. N.; Leshem, R.; Sergiou, K.; Fernandez Carro, M. L.; Uzuner, E.; Mole, H.; Telfer, B. A.; Wilcock, D. J.; Smith, M. P.; Kunii, K.; Perl, N. R.; Lorigan, P.; Williams, K. J.; Rao, P. E.; Nagaraju, R. T.; Niepel, M.; Hurlstone, A. F. L.
10.1101/2022.11.18.517143 — cancer biology — Posted on 2022-11-22
1129 Heterogeneous distribution of sex ratio distorters in natural populations of the isopod Armadillidium vulgare
Durand, S.; Lheraud, B.; Giraud, I.; Bech, N.; Grandjean, F.; Rigaud, T.; Peccoud, J.; Cordaux, R.
10.1101/2022.09.29.510044 — evolutionary biology — Posted on 2022-11-22
1130 Lipid Desaturation Regulates the Balance between Self-renewal and Differentiation in Mouse Blastocyst-derived Stem Cells
Thomas, C.; Haimson, R. B.; Zacharia, A.; Orih, P.; Shehadeh, A.; Saidemberg, D.; Kogan, N. M.; Alfandary, S.; Serruya, R.; Dagan, A.; Petit, I.; Moussaieff, A.
10.1101/2022.07.28.501839 — developmental biology — Posted on 2022-11-22
1131 An SNF2 helicase-like protein links mitotic transcription termination to sister chromatid resolution
Carmo, C.; Coelho, J.; Silva, R.; Tavares, A.; Boavida, A.; Gaetani, P.; Martinho, R. G.; Oliveira, R. A.
10.1101/2022.11.21.517340 — cell biology — Posted on 2022-11-22
1132 The velvet family proteins mediate low resistance to isoprothiolane in Magnaporthe oryzae
Meng, F.-Z.; Wang, Z.-Q.; Luo, M.; Wei, W.-K.; Yin, L.-F.; Yin, W.-X.; Schnabel, G.; Luo, C.
10.1101/2022.11.20.517298 — microbiology — Posted on 2022-11-22
1133 Genome editing of an African elite rice variety confers resistance against endemic and emerging Xanthomonas oryzae pv. oryzae strains
Schepler-Luu, V.; Sciallano, C.; Stiebner, M.; Ji, C.; Boulard, G.; Diallo, A.; Auguy, F.; Char, S. N.; Arra, Y.; Schenstnyi, K.; Buchholzer, M.; Loo, E. P. I.; Bilaro, A. L.; Lihepanyama, D.; Mkuya, M.; Murori, R.; Oliva, R.; Cunnac, S.; Yang, B.; Szurek, B.; Frommer, W. B.
10.1101/2022.11.20.517251 — plant biology — Posted on 2022-11-22
1135 Matchtigs: minimum plain text representation of kmer sets
Schmidt, S.; Khan, S.; Alanko, J.; Pibiri, G. E.; Tomescu, A. I.
10.1101/2021.12.15.472871 — bioinformatics — Posted on 2022-11-22
1136 AlphaFold2-based fusion design deciphers crucial role of the E3 UFL1 N-terminal helix in E2 UFC1 binding and ufmylation
Banerjee, S.; Varga, J. K.; Kumar, M.; Zoltsman, G.; Isupov, M. N.; Rosenzweig, R.; Schueler-Furman, O.; Wiener, R.
10.1101/2022.09.15.508077 — biochemistry — Posted on 2022-11-22
1137 Behavioral and neural evidence that robots are implicitly perceived as a threat
Wei, Z.; Chen, Y.; Ren, J.; Piao, Y.; Zhang, P.; Zhao, Q.; Zha, R.; Qiu, B.; Zhang, D.; Bi, Y.; Han, S.; Li, C.; Zhang, X.
10.1101/2021.08.13.456053 — neuroscience — Posted on 2022-11-22
1138 Genome-wide prediction of dominant and recessive neurodevelopmental disorder risk genes
Dhindsa, R. S.; Weido, B.; Dhindsa, J. S.; Shetty, A. J.; Sands, C.; Petrovski, S.; Vitsios, D.; Zoghbi, A. W.
10.1101/2022.11.21.517436 — genetics — Posted on 2022-11-21
1139 Homunculus Interruptus: A motor association area in the depth of the central sulcus
Jensen, M. A.; Huang, H.; Ojeda Valencia, G.; Klassen, B.; van den Boom, M.; Kaufmann, T.; Schalk, G.; Brunner, P.; Hermes, D.; Worrell, G.; Miller, K. J.
10.1101/2022.11.20.517292 — neuroscience — Posted on 2022-11-21
1140 Learning Fast and Slow: Increased cortical plasticity leads to memory interference and enhanced hippocampal-cortical interactions
Navarro-Lobato, I.; Aleman-Zapata, A.; Samanta, A.; Bogers, M.; Narayanan, S.; Rayan, A.; Alonso, A.; van der Meij, J.; Khamassi, M.; Khan, Z. U.; Genzel, L.
10.1101/2022.11.21.517356 — neuroscience — Posted on 2022-11-21
1141 Disentangling the complex gene interaction networks between rice and the blast fungus identifies a new pathogen effector
Sugihara, Y.; Abe, Y.; Takagi, H.; Abe, A.; Shimizu, M.; Ito, K.; Kanzaki, E.; Oikawa, K.; Kourelis, J.; Langner, T.; Win, J.; Bialas, A.; Ludke, D.; Contreras, M. P.; Chuma, I.; Saitoh, H.; Kobayashi, M.; Zheng, S.; Tosa, Y.; Banfield, M. J.; Kamoun, S.; Terauchi, R.; Fujisaki, K.
10.1101/2022.07.19.500555 — plant biology — Posted on 2022-11-21
1143 The Effect of Polymer Length in Phase Separation
Valdes-Garcia, G.; Gamage, K.; Smith, C.; Martirosova, K.; Feig, M.; Lapidus, L.
10.1101/2022.11.21.517354 — biophysics — Posted on 2022-11-21
1144 Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase
Scheerer, D.; Adkar, B. V.; Bhattacharyya, S.; Levy, D.; Iljina, M.; Riven, I.; Dym, O.; Haran, G.; Shakhnovich, E.
10.1101/2022.11.21.517316 — biophysics — Posted on 2022-11-21
1146 Welcome to the big leaves: best practices for improving genome annotation in non-model plant genomes
Vuruputoor, V. S.; Monyak, D.; Fetter, K. C.; Webster, C.; Zaman, S.; Bhattarai, A.; Bennett, J.; McEvoy, S.; Shrestha, B.; Caballero, M.; Wegrzyn, J.
10.1101/2022.10.03.510643 — bioinformatics — Posted on 2022-11-21
1147 Exome-wide benchmark of difficult-to-sequence regions using short-read next-generation DNA sequencing
Hijikata, A.; Suyama, M.; Kikugawa, S.; Matoba, R.; Naruto, T.; Enomoto, Y.; Kurosawa, K.; Harada, N.; Yanagi, K.; Kaname, T.; Miyako, K.; Takazawa, M.; Sasai, H.; Hosokawa, J.; Itoga, S.; Yamaguchi, T.; Kosho, T.; Matsubara, K.; Kuroki, Y.; Fukami, M.; Adachi, K.; Nanba, E.; Tsuchida, N.; Uchiyama, Y.; Matsumoto, N.; Nishimura, K.; Ohara, O.
10.1101/2022.11.20.517268 — genomics — Posted on 2022-11-21
1148 An updated evolutionary history and taxonomy of Mycobacterium tuberculosis lineage 5, also called M. africanum
Sahal, M. R.; Senelle, G.; La, K.; Molina-Moya, B.; Dominguez, J. A.; Panda, T.; Cambau, E.; Refregier, G.; Guyeux, C.; Sola, C. N.
10.1101/2022.11.21.517336 — genomics — Posted on 2022-11-21
1149 The Mangrove Microbiome of the Malay Peninsula
Wainwright, B. J.; Hickman, K. J. E.; Millar, T.; Bowen, L.; Lee, J. N.; Yeo, Z. Y.; Huang, D.; Zahn, G. L.
10.1101/2022.11.21.517418 — ecology — Posted on 2022-11-21
1150 Ratiometric sensing of Pnt and Yan transcription factor levels confers ultrasensitivity to photoreceptor fate transitions in Drosophila
Bernasek, S. M.; Hur, S. S.; Pelaez, N.; Boisclair Lachance, J.-F.; Bakker, R.; Navarro, H. T.; Sanchez-Luege, N.; Amaral, L. A. N.; Bagheri, N.; Rebay, I.; Carthew, R. W.
10.1101/430744 — developmental biology — Posted on 2022-11-21
1151 Structural analysis of Toxoplasma gondii sortilin
Honfozo, A.; Ghouil, R.; Alayi, T. D.; Ouldali, M.; Arteni, A.-A.; Atindehou, C. M.; Fanou, L. A.; Hathout, Y.; Zinn-Justin, S.; Tomavo, S.
10.1101/2022.11.17.516902 — cell biology — Posted on 2022-11-21
1152 Interferon-gamma Elicits Pathological Hallmarks of ALS in Human Motor Neurons
Chun, C.; Lee, J. H.; Bothwell, M.; Nghiem, P.; Smith, A. S. T.; Mack, D. L.
10.1101/2022.11.18.517141 — neuroscience — Posted on 2022-11-21
1153 An integrated resource for functional and structural connectivity of the marmoset brain
Tian, X.; Chen, Y.; Majka, P.; Szczupak, D.; Sanz-Perl, Y.; Yen, C. C.-C.; Tong, C.; Feng, F.; Jiang, H.; Glen, D.; Deco, G.; Rosa, M. G. P.; Silva, A. C.; Liang, Z.; Liu, C.
10.1101/2021.11.12.468389 — neuroscience — Posted on 2022-11-21
1156 3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay
Zhang, Y.; Jiang, F.; Zhao, Y. C.; Wang, Y.; Aye, S. S. S.; Cho, A.-N.; Fang, G.; Cox, C. D.; Zreiqat, H.; Lu, Z. F.; Lu, H.; Ju, L. A.
10.1101/2022.11.19.517181 — bioengineering — Posted on 2022-11-21
1158 Natural strongyle infection reduces relative abundance of inflammation-inducing Prevotella in wild primates
Cizauskas, C. A.; Washburne, A. D.; Knelman, J. E.; Hansen, C. B.; Nderitu, A. M.; Esinyon, P. L.; Dobson, A.; Graham, A. L.
10.1101/2022.06.02.494558 — ecology — Posted on 2022-11-21
1159 Dynamic of Mayaro virus transmission between Aedes aegypti and Culex quinquefasciatus mosquitoes and a mice model
Krokovsky, L.; Lins, C. R. B.; Guedes, D. R. D.; Wallau, G. d. L.; Ayres, C. F. J.; Paiva, M. H. S.
10.1101/2022.11.20.517299 — molecular biology — Posted on 2022-11-21
1160 arfA antisense RNA regulates MscL excretory activity
Morra, R.; Pratama, F.; Butterfield, T.; Tomazetto, G.; Young, K.; Lopez Perez, R.; Dixon, N.
10.1101/2022.11.21.517365 — molecular biology — Posted on 2022-11-21
1164 Flow cytometry-based biomarker assay for in vitro identification of heat tolerance conferring coral symbionts
Buerger, P.; Buler, M.; Yeap, H. L.; Edwards, O. R.; van Oppen, M. J.; John, O. G.; Court, L.
10.1101/2022.11.21.517290 — microbiology — Posted on 2022-11-21
1165 The role of bacterial size, shape and surface in macrophage engulfment of uropathogenic E. coli cells
Peterson, E.; Söderström, B.; Prins, N.; Le, G. H. B.; Hartley-Tassell, L. E.; Evenhuis, C.; Birkholm Gronnemose, R.; Andersen, T. E.; Moller-Jensen, J.; Iosifidis, G.; Duggin, I. G.; Saunders, B.; Bottomley, A. L.; Harry, E. J.
10.1101/2022.11.20.517300 — microbiology — Posted on 2022-11-21
1167 Spherocytosis-related L1340P mutation in ankyrin affects its interactions with spectrin
Machnicka, B.; Czogalla, A.; Boguslawska, D. M.; Stasiak, P.; Sikorski, A. F.
10.1101/2022.11.21.517333 — biochemistry — Posted on 2022-11-21
1169 Discovery and biosynthetic assessment of Streptomyces ortus sp nov. isolated from a deep-sea sponge
Williams, S. E.; Back, C. R.; Best, E.; Mantell, J.; Stach, J. E. M.; Williams, T. A.; Race, P. R.; Curnow, P.
10.1101/2022.11.21.517041 — genomics — Posted on 2022-11-21
1170 FAP106 is an interaction hub required for assembly of conserved and lineage-specific microtubule inner proteins at the cilium inner junction
Shimogawa, M. M.; Wijono, A. S.; Wang, H.; Zhang, J.; Sha, J.; Szombathy, N.; Vadakkan, S.; Pelayo, P.; Jonnalagadda, K.; Wohlschlegel, J. A.; Zhou, Z. H.; Hill, K.
10.1101/2022.11.11.516029 — cell biology — Posted on 2022-11-21
1171 Atomistic structure of the interlocking claw-like amyloid fibril of full-length glucagon
Jeong, H.; Lin, Y.; Kim, J. H.; Yu, W.; Heo, Y.; Won, H.-S.; Okumura, M.; Lee, Y.-H.
10.1101/2022.11.21.517306 — molecular biology — Posted on 2022-11-21
1173 mRNA targeting eliminates the need for the signal recognition particle during membrane protein insertion in bacteria
Sarmah, P.; Shang, W.; Origi, A.; Licheva, M.; Kraft, C.; Ulbrich, M. H.; Lichtenberg, E.; Wilde, A.; Koch, H.-G.
10.1101/2022.11.21.517368 — microbiology — Posted on 2022-11-21
1175 Longitudinal dynamics of the human vaginal ecosystem across the reproductive cycle
Costello, E. K.; DiGiulio, D. B.; Robaczewska, A.; Symul, L.; Wong, R. J.; Shaw, G. M.; Stevenson, D. K.; Holmes, S. P.; Kwon, D. S.; Relman, D. A.
10.1101/2022.11.20.517263 — microbiology — Posted on 2022-11-21
1178 Patterns and determinants of the global herbivorous mycobiome
Meili, C.; Jones, A. L.; Arreola, A. X.; Habel, j.; Pratt, C. J.; Hanafy, R. A.; Wang, Y.; Yassin, A. S.; TagElDein, M. A.; Moon, C.; Janssen, P. H.; Shrestha, M.; Rajbhandari, P.; Nagler, M.; Vinzelj, J. M.; Podmirseg, S. M.; Stajich, J. E.; Goetsch, A. L.; Hayes, J.; Young, D.; Fliegerova, K.; Grilli, D. J.; Vodicka, R.; Moniello, G.; Mattiello, S.; Kashef, M. T.; Nagy, Y. I.; Edwards, J. A.; Dagar, S. S.; Foote, A. P.; Youssef, N. H.; Elshahed, M. S.
10.1101/2022.11.21.517404 — microbiology — Posted on 2022-11-21
1183 Tetraspanner-based nanodomains modulate BAR domain-induced membrane curvature
Haase, D.; Rasch, C.; Keller, U.; Elting, A.; Wittmar, J.; Janning, A.; Kahms, M.; Schuberth, C.; Klingauf, J.; Wedlich-Soldner, R.
10.1101/2022.11.21.517310 — cell biology — Posted on 2022-11-21
1184 Divisome core complex in bacterial cell division revealed by cryo-EM
Kashammer, L.; van den Ent, F.; Jeffery, M.; Jean, N. L.; Hale, V. L.; Lowe, J.
10.1101/2022.11.21.517367 — molecular biology — Posted on 2022-11-21
1185 Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy
Sanches Peres, R.; Thomas, T.; Friedrich, M.; Pohin, M.; Pearson, C.; Ferreira, R.; Mann, E.; Trzupek, D.; Rich-Griffin, C.; Jainarayanan, A.; Jones, K.; Gu, Y.; Todd, J.; Uhlig, H.; Buckley, C.; Dendrou, C.; Travis, S.; Powrie, F.
10.1101/2022.11.21.517257 — immunology — Posted on 2022-11-21
1186 De novo identification of CD4+ T cell epitopes
Zdinak, P.; Grebinoski, S.; Torrey, J.; Zarate-Martinez, E.; Hicks, L.; Ranjan, R.; Trivedi, N.; Arshad, S.; Anderson, M.; Vignali, D.; Joglekar, A. V.
10.1101/2022.11.21.517373 — immunology — Posted on 2022-11-21
1187 Ultrasound treatment inhibits SARS-CoV-2 in vitro infectivity
Veras, F. P.; Martins, R.; Arruda, E.; Cunha, F. Q.; Bruno, O. M.
10.1101/2022.11.21.517338 — biophysics — Posted on 2022-11-21
1189 Differential haplotype expression in class I MHC genes during SARS-CoV-2 infection of human lung cell lines
Francisco Junior, R. d. S.; Temerozo, J. R.; Ferreira, C. d. S.; Martins, Y.; Souza, T. M. L.; Medina-Acosta, E.; de Vasconcelos, A. T. R.
10.1101/2022.11.20.517193 — genomics — Posted on 2022-11-21
1193 SARS-CoV-2 exposure in Norwegian rats (Rattus norvegicus) from New York City
Wang, Y.; Lenoch, J.; Kohler, D.; DeLiberto, T.; Tang, C.; Li, T.; Tao, Y.; Guan, M.; Compton, S.; Zeiss, C. J.; Hang, J.; Wan, X.-F.
10.1101/2022.11.18.517156 — microbiology — Posted on 2022-11-21
1194 Paxlovid-like nirmatrelvir/ritonavir fails to block SARS-CoV-2 transmission in ferrets
Cox, R.; Lieber, C. M.; Wolf, J. D.; Karimi, A.; Lieberman, N. A. P.; Sticher, Z. M.; Roychoudhury, P.; Andrews, M. K.; Krueger, R. E.; Natchus, M. G.; Painter, G. R.; Kolykhalov, A.; Greninger, A. L.; Plemper, R. K.
10.1101/2022.11.20.517271 — microbiology — Posted on 2022-11-21
1195 Comparative aerosol and surface stability of SARS-CoV-2 Variants of Concern
Bushmaker, T.; Yinda, K. C.; Morris, D.; Holbrook, M.; Gamble, A.; Adney, D.; Bushmaker, C.; van Doremalen, N.; Fischer, R.; Plowright, R.; Lloyd-Smith, J. O.; Munster, V.
10.1101/2022.11.21.517352 — microbiology — Posted on 2022-11-21
1197 Novel mRNA vaccines encoding Monkeypox virus M1R and A35R protect mice from a lethal virus challenge
Hou, F.; Zhang, Y.; Liu, W.; Murad, Y.; Xu, J.; Yu, Z.; Hua, X.; Song, Y.; Ding, J.; Huang, C.; Jia, W.; Yang, X.
10.1101/2022.11.19.517190 — immunology — Posted on 2022-11-21
1198 SARS-CoV-2 variant transition dynamics are associated with vaccination rates, number of co-circulating variants, and natural immunity
Beesley, L. J.; Moran, K. R.; Wagh, K.; Castro, L.; Theiler, J.; Yoon, H.; Fischer, W.; Hengartner, N. W.; Korber, B.; Del Valle, S.
10.1101/2022.11.18.517139 — bioinformatics — Posted on 2022-11-21
1201 Pleural macrophages translocate to the lung during infection to promote improved influenza outcomes
Stumpff, J. P.; Kim, S. Y.; Forero, A.; Nishida, A.; Steuerman, Y.; Gat-Viks, I.; Nair, M. G.; Morrison, J.
10.1101/2022.05.25.493482 — microbiology — Posted on 2022-11-21
1203 Ensemble-specific deficit in neuronal intrinsic excitability in aged mice
Chen, L.; Francisco, T. R.; Baggetta, A. M.; Zaki, Y.; Ramirez, S.; Clem, R.; Shuman, T.; Cai, D. J.
10.1101/2022.06.02.494525 — neuroscience — Posted on 2022-11-21
1205 A deep learning and digital archaeology approach for mosquito repellent discovery
Wei, J. N.; Vlot, M.; Sanchez-Lengeling, B.; Lee, B. K.; Berning, L.; Vos, M. W.; Henderson, R. W.; Qian, W. W.; Ando, D. M.; Groetsch, K. M.; Gerkin, R. C.; Wiltschko, A. B.; Dechering, K. J.
10.1101/2022.09.01.504601 — bioengineering — Posted on 2022-11-21
1206 Rational optimization of a transcription factor activation domain inhibitor
Basu, S.; Martinez-Cristobal, P.; Pesarrodona, M.; Frigole-Vivas, M.; Szulc, E.; Lewis, M.; Banuelos, A.; Sanchez-Zarzalejo, C.; Bielskute, S.; Zhu, J.; Pombo-Garcia, K.; Garcia-Cabau, C.; Batlle, C.; Mateos, B.; Biesaga, M.; Escobedo, A.; Bardia, L.; Verdaguer, X.; Ruffoni, A.; Mawji, N. R.; Wang, J.; Tam, T.; Brun-Heath, I.; Ventura, S.; Meierhofer, D.; Garcia, J.; Robustelli, P.; Stracker, T. H.; Sadar, M. D.; Riera, A.; Hnisz, D.; Salvatella, X.
10.1101/2022.08.18.504385 — biochemistry — Posted on 2022-11-21
1207 Large scale functional screen identifies genetic variants with splicing effects in modern and archaic humans
Rong, S.; Neil, C. R.; Maguire, S.; Meremikwu, I. C.; Meyerson, M.; Evans, B. J.; Fairbrother, W. G.
10.1101/2022.11.20.515225 — genomics — Posted on 2022-11-21
1210 The midbody and midbody remnant are assembly sites for RNA and active translation
Park, S.; Dahn, R. D.; Kurt, E.; Presle, A.; VandenHeuvel, K.; Moravec, C.; Jambhekar, A.; Olukoga, O. K.; Shepherd, J. D.; Echard, A. D.; Blower, M. D.; Skop, A. R.
10.1101/2022.11.01.514698 — cell biology — Posted on 2022-11-21
1211 Transcriptome network analysis implicates CX3CR1-positive type 3 dendritic cells in non-infectious uveitis
Hiddingh, S.; Pandit, A.; Verhagen, F.; Rijken, R.; Servaas, N.; Komer-Wichers, R.; Dam-van Loon, N. t.; Imhof, S. S.; Radstake, T.; de Boer, J. H.; Kuiper, J. J. W.
10.1101/2021.11.16.468816 — immunology — Posted on 2022-11-21
1213 An Agent-Based Model of monocyte differentiation into Tumour-Associated Macrophages in Chronic Lymphocytic Leukemia
Verstraete, N.; Marku, M.; Domagala, M.; Bordenave, J.; Arduin, H.; Fournie, J. J.; Ysebaert, L.; Poupot, M.; Pancaldi, V.
10.1101/2021.12.17.473137 — systems biology — Posted on 2022-11-21
1219 GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data
Ajaib, S. A.; Lodha, D.; Pollock, S.; Hemmings, G.; Finetti, M.; Gusnanto, A.; Chakrabarty, A.; Ismail, A.; Wilson, E.; Varn, F. S.; Hunter, B.; Filby, A.; Brockman, A. A.; McDonald, D.; Verhaak, R.; Ihrie, R. A.; Stead, L. F.
10.1101/2022.11.19.517187 — cancer biology — Posted on 2022-11-21
1220 Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies
Planas, D.; Bruel, T.; Staropoli, I.; Guivel-Benhassine, F.; Porrot, F.; Maes, P.; Grzelak, L.; Prot, M.; Mougari, S.; Planchais, C.; Puech, J.; Saliba, M.; Sahraoui, R.; Femy, F.; Morel, N.; Dufloo, J.; Sanjuan, R.; Mouquet, H.; Andre, E.; Hocqueloux, L.; Simon-Loriere, E.; Veyer, D.; Prazuck, T.; Pere, H.; Schwartz, O.
10.1101/2022.11.17.516888 — microbiology — Posted on 2022-11-21
1221 The use of non-functional clonotypes as a natural calibrator for quantitative bias correction in adaptive immune receptor repertoire profiling
Smirnova, A. O.; Miroshnichenkova, A. M.; Olshanskaya, Y. V.; Maschan, M. A.; Lebedev, Y. B.; Chudakov, D. M.; Mamedov, I.; Komkov, A. Y.
10.1101/2021.03.24.436794 — immunology — Posted on 2022-11-21
1223 Smart squirrels use a mortise-tenon structure to fix nuts on understory twigs
Xu, H.; Xia, L.; Spence, J. R.; Lin, M.; Lu, C.; Li, Y.; Chen, J.; Luo, T.; Li, Y.; Fang, S.
10.1101/2022.11.20.517261 — ecology — Posted on 2022-11-21
1224 A multispecific antibody prevents immune escape and confers pan-SARS-CoV-2 neutralization
Misasi, J.; Wei, R. R.; Wang, L.; Pegu, A.; Wei, C.-J.; Oloniniyi, O.; Zhou, T.; Moliva, J. I.; Zhao, B.; Choe, M.; Yang, E. S.; Zhang, Y.; Boruszczak, M.; Chen, M.; Leung, K.; Li, J.; Yang, Z.-Y.; Andersen, H.; Carlton, K.; Godbole, S.; Harris, D. R.; Henry, A. R.; Ivleva, V. B.; Lei, P.; Liu, C.; Longobardi, L.; Merriam, J. S.; Nase, D.; Olia, A. S.; Pessaint, L.; Porto, M.; Shi, W.; Wolff, J. J.; Douek, D. C.; Suthar, M. S.; Gall, J.; Koup, R. A.; Kwong, P. D.; Mascola, J. R.; Nabel, G. J.; Sullivan, N. J.
10.1101/2022.07.29.502029 — immunology — Posted on 2022-11-21
1225 Inhibition of ADORA1 attenuates hepatic steatosis by gut microbiota-derived acetic acid from Astragalus polysaccharides
Hong, Y.; Zheng, N.; He, X.; Zhong, J.; Ma, J.; Zhao, A.; Zheng, X.; Gu, Y.; Yao, J.; Li, Y.; Yuan, L.; Lin, M.; Lu, X.; Ping, J.; Song, P.; Li, B.; Han, R.; Sheng, L.; Zhang, W.; Ding, K.; Liu, J.; Jia, W.; Li, H.
10.1101/639195 — physiology — Posted on 2022-11-21
1226 Macroscale Thalamic Functional Organization Disturbances And Underlying Core Cytoarchitecture In Early-Onset Schizophrenia
Fan, Y.-S.; Xu, Y.; Bayrak, S.; Shine, J.; Wan, B.; Li, H.; Li, L.; Yang, S.; Meng, Y.; Valk, S. L.; Chen, H.
10.1101/2022.05.11.489776 — neuroscience — Posted on 2022-11-21
1228 Species-conserved mechanisms of cognitive flexibility in complex environments
Baehner, F.; Popov, T.; Hermann, S.; Boehme, N.; Merten, T.; Zingone, H.; Koppe, G.; Meyer-Lindenberg, A.; Toutounji, H.; Durstewitz, D.
10.1101/2022.11.14.516439 — neuroscience — Posted on 2022-11-21
1230 De novo analysis of bulk RNA-seq data at spatially resolved single-cell resolution
Liao, J.; Qian, J.; Fang, Y.; Chen, Z.; Zhuang, X.; Zhang, N.; Shao, X.; Hu, Y.; Yang, P.; Cheng, J.; Hu, Y.; Yu, L.; Yang, H.; Zhang, J.; Lu, X.; Shao, L.; Wu, D.; Gao, Y.; Chen, H.; Fan, X.
10.1101/2022.01.15.476472 — bioinformatics — Posted on 2022-11-21
1231 Initial niche condition determines the aging speed and regenerative activity of quiescent cells
Liu, Q.; Sheng, N.; Zhang, Z.; He, C.; Zhao, Y.; Sun, H.; Chen, J.; Yang, X.; Tang, C.
10.1101/2022.09.06.506737 — cell biology — Posted on 2022-11-21
1233 Hierarchical whole-brain dynamics of auditory predictive coding at the fine-grained milliseconds level
Bonetti, L.; Fernandez-Rubio, G.; Carlomagno, F.; Pantazis, D.; Vuust, P.; Kringelbach, M. L.
10.1101/2022.11.19.517195 — neuroscience — Posted on 2022-11-21
1236 HSP70-binding motifs function as protein quality control degrons
Abildgaard, A. B.; Voutsinos, V.; Petersen, S. D.; Larsen, F. B.; Kampmeyer, C.; Johansson, K. E.; Stein, A.; Ravid, T.; Andreasson, C.; Jensen, M. K.; Lindorff-Larsen, K.; Hartmann-Petersen, R.
10.1101/2021.12.22.473789 — biochemistry — Posted on 2022-11-21
1238 Large scale functional screen identifies genetic variants with splicing effects in modern and archaic humans
Rong, S.; Neil, C. R.; Maguire, S.; Meremikwu, I. C.; Meyerson, M.; Evans, B. J.; Fairbrother, W. G.
10.1101/2022.11.20.515225 — genomics — Posted on 2022-11-20
1239 Homeotic compartment curvature and tension control spatiotemporal folding dynamics.
Villedieu, A.; Alpar, L.; Gaugue, I.; Joudat, A.; Graner, F.; Bosveld, F.; Bellaiche, Y.
10.1101/2022.11.19.517180 — developmental biology — Posted on 2022-11-21
1242 Resting-State fMRI reveals Longitudinal Alterations in Brain Network Connectivity in a Mouse Model of Huntington's Disease
Vasilkovska, T.; Adhikari, M. H.; Van Audekerke, J.; Pustina, D.; Cachope, R.; Tang, H.; Liu, L.; Munoz-Sanjuan, I.; Van der Linden, A.; Verhoye, M.
10.1101/2022.11.19.517166 — neuroscience — Posted on 2022-11-21
1243 Matchtigs: minimum plain text representation of kmer sets
Schmidt, S.; Khan, S.; Alanko, J.; Pibiri, G. E.; Tomescu, A. I.
10.1101/2021.12.15.472871 — bioinformatics — Posted on 2022-11-21
1250 Robust and Highly Efficient Extractions of Proteins from Bones enable Deep, High-Throughput Proteomic Quantification to Gain Insights into Bone Biology
Rose, J. P.; Schurman, C. A.; King, C. D.; Bons, J.; Burton, J. B.; Patel, S. K.; O'Broin, A.; Alliston, T.; Schilling, B.
10.1101/2022.11.20.517228 — biochemistry — Posted on 2022-11-20
1251 The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch.
Photenhauer, A. L.; Cerqueira, F. M.; Villafuerte-Vega, R.; Armbruster, K. M.; Marecek, F.; Chen, T.; Wawrzak, Z.; Hopkins, J. B.; Kooi, C. W. V.; Janecek, S.; Ruotolo, B. T.; Koropatkin, N. M.
10.1101/2022.11.20.514607 — molecular biology — Posted on 2022-11-20
1255 Global connectivity and networks of marine reserves
McDowell, J.; Mouillot, D.; Pollock, L.; Andrello, M.; Velez, L.; Barrier, N.; Manel, S.
10.1101/2022.11.20.515214 — systems biology — Posted on 2022-11-20
1256 Split selectable marker mediated gene stacking in plants
Yuan, G.; Lu, H.; De, K.; Hassan, M. M.; Wellington, M.; Tuskan, G. A.; Yang, X.
10.1101/2022.11.19.517202 — plant biology — Posted on 2022-11-20
1257 Maresin 1 Repletion Improves Muscle Regeneration After Volumetric Muscle Loss
Castor-Macias, J. A.; Larouche, J. A.; Wallace, E. C.; Spence, B. D.; Eames, A.; Yang, B. A.; Davis, C.; Brooks, S. V.; Maddipati, K. R.; Markworth, J. F.; Aguilar, C. A.
10.1101/2022.11.19.517113 — physiology — Posted on 2022-11-20
1259 A robotic system for automated genetic manipulation and analysis of Caenorhabditis elegans on agar media
Li, Z.; Fouad, A. D.; Bowlin, P.; Fan, Y.; He, S.; Chang, M.-C.; Du, A.; Teng, C.; Kassouni, A.; Ji, H.; Raizen, D. M.; Fang-Yen, C.
10.1101/2022.11.18.517134 — bioengineering — Posted on 2022-11-20
1262 Artisanal and farmers bread making practices differently shape fungal species community composition in French sourdoughs
Michel, E.; Masson, E.; Bubbendorf, S.; Lapicque, L.; Nidelet, T.; Segond, D.; Guezenec, S.; Marlin, T.; Devillers, H.; Rue, O.; Onno, B.; Legrand, J.; Sicard, D.
10.1101/679472 — ecology — Posted on 2022-11-20
1263 Ventral striatal dopamine encodes unique properties of visual stimuli in mice
Gonzalez, L. S.; Fisher, A. A.; D'Souza, S. P.; Cotella, E. M.; Lang, R. A.; Robinson, J. E.
10.1101/2022.09.20.508670 — neuroscience — Posted on 2022-11-20
1265 Subcortical circuit dysfunctions delay perceptual decision-making in autism models
Burnett, L. E.; Koppensteiner, P.; Symonova, O.; Masson, T.; Vega-Zuniga, T.; Contreras, X.; Ruelicke, T.; Shigemoto, R.; Novarino, G.; Joesch, M.
10.1101/2022.10.11.511691 — neuroscience — Posted on 2022-11-20
1267 MSP1 encodes an essential RNA-binding PPR factor required for nad1 maturation and complex I biogenesis in Arabidopsis mitochondria
Best, C.; Mizrahi, R.; Edris, R.; Tang, H.; Zer, H.; Colas des Francs-Small, C.; Finkel, O. M.; Zhu, H.; Small, I. D.; Ostersetzer, O.
10.1101/2022.11.12.516219 — plant biology — Posted on 2022-11-20
1269 GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data
Ajaib, S. A.; Lodha, D.; Pollock, S.; Hemmings, G.; Finetti, M.; Gusnanto, A.; Chakrabarty, A.; Ismail, A.; Wilson, E.; Varn, F. S.; Hunter, B.; Filby, A.; Brockman, A. S.; McDonald, D.; Verhaak, R.; Ihrie, R. A.; Stead, L. F.
10.1101/2022.11.19.517187 — cancer biology — Posted on 2022-11-20
1271 Optogenetic dissection of transcriptional repression in a multicellular organism
Zhao, J.; Lammers, N. C.; Alamos, S.; Kim, Y. J.; Martini, G.; Garcia, H. G.
10.1101/2022.11.20.517211 — biophysics — Posted on 2022-11-20
1277 Antagonistic antimalarial properties of a methoxyamino chalcone derivative and 3-hydroxypyridinones in combination with dihydroartemisinin against Plasmodium falciparum
Kampoun, T.; Koonyosying, P.; Ruangsuriya, J.; Prommana, P.; Shaw, P. J.; Kamchonwongpaisan, S.; Suwito, H.; Puspaningsih, N. N.; Uthaipibull, C.; Srichairatanakool, S.
10.1101/2022.11.19.517177 — biochemistry — Posted on 2022-11-20
1278 Long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity
Weller, C. A.; Andreev, I.; Chambers, M. J.; Park, M.; NISC Comparative Sequencing Program, ; Bloom, J. S.; Sadhu, M. J.
10.1101/2022.11.19.517216 — genomics — Posted on 2022-11-20
1279 Robust identification of extrachromosomal DNA and genetic variants using multiple genetic abnormality sequencing (MGA-Seq)
Lin, D.; Zou, Y.; Wang, J.; Xiao, Q.; Lin, F.; Zhang, N.; Teng, Z.; Li, S.; Wei, Y.; Zhou, F.; Yin, R.; Zhang, S.; Wu, C.; Zhang, J.; Hu, S.; Dong, S.; Li, X.; Ye, S.; Sun, H.; Cao, G.
10.1101/2022.11.18.517160 — genomics — Posted on 2022-11-20
1281 Protected area planning to conserve biodiversity in an uncertain future
Schuster, R.; Buxton, R.; Hanson, J. O.; Binley, A. D.; Pittman, J.; Tulloch, V.; La Sorte, F. A.; Roehrdanz, P. R.; Verburg, P. H.; Rodewald, A. D.; Wilson, S.; Possingham, H. P.; Bennett, J. R.
10.1101/2022.11.18.517054 — ecology — Posted on 2022-11-20
1282 Homeotic compartment curvature and tension control spatiotemporal folding dynamics.
Villedieu, A.; Alpar, L.; Gaugue, I.; Joudat, A.; Graner, F.; Bosveld, F.; Bellaiche, Y.
10.1101/2022.11.19.517180 — developmental biology — Posted on 2022-11-20
1284 Improved high-dimensional multivariate autoregressive model estimation of human electrophysiological data using fMRI priors
Nagle, A.; Gerrelts, J. P.; Krause, B.; Boes, A. D.; Bruss, J. E.; Nourski, K. V.; Banks, M. I.; Van Veen, B.
10.1101/2022.11.18.516669 — neuroscience — Posted on 2022-11-20
1290 Canagliglozin extends life span and leads to less weight gain in C57BL6 male mice
Habeos, E. E.; Filippopoulou, F.; Kanakis, M.; Habeos, G. I.; Lagoumintzis, G.; Taraviras, S.; Chartoumpekis, D. V.
10.1101/2022.11.20.517248 — physiology — Posted on 2022-11-20
1293 Using Attention-based Deep Learning to Predict ERG:TMPRSS2 Fusion Status in Prostate Cancer from Whole Slide Images
Omar, M.; Xu, Z.; Rand, S. B.; Mohammad, M.; Salles, D. C.; Schaeffer, E. M.; Robinson, B. D.; Lotan, T. L.; Loda, M.; Marchionni, L.
10.1101/2022.11.18.517111 — pathology — Posted on 2022-11-20
1294 Computational structure prediction methods enable the systematic identification of oncogenic mutations
Fu, X.; Reglero, C.; Swamy, V.; Loh, J. W.; Khiabanian, H.; Albero, R.; Forouhar, F.; Al Quraishi, M.; Ferrando, A. A.; Rabadan, R.
10.1101/2022.11.18.517015 — cancer biology — Posted on 2022-11-20
1296 Lipid nanodisc scaffold and size alters the structure of a pentameric ligand-gated ion channel
Dalal, V.; Arcario, M. J.; Petroff, J. T.; Dietzen, N. M.; Rau, M. J.; Fitzpatrick, J. A. J.; Brannigan, G.; Cheng, W. W. L.
10.1101/2022.11.20.517256 — biophysics — Posted on 2022-11-20
1297 An Automatized Workflow to Study Mechanistic Indicators for Driver Gene Prediction with Moonlight
Saksager, A.; Nourbakhsh, M.; Tom, N.; Chen, X. S.; Colaprico, A.; Olsen, C.; Tiberti, M.; Papaleo, E.
10.1101/2022.11.18.517066 — bioinformatics — Posted on 2022-11-20
1298 CAGEE: computational analysis of gene expression evolution
Bertram, J.; Fulton, B.; Tourigny, J.; Pena-Garcia, Y.; Moyle, L. C.; Hahn, M. W.
10.1101/2022.11.18.517074 — bioinformatics — Posted on 2022-11-20
1299 SurvBoard: Standardised Benchmarking for Multi-omics Cancer Survival Models
Wissel, D.; Janakarajan, N.; Grover, A.; Toniato, E.; Martinez, M. R.; Boeva, V.
10.1101/2022.11.18.517043 — bioinformatics — Posted on 2022-11-20
1302 Bioinformatically predicted emulsifying peptides and potato protein hydrolysate improves the oxidative stability of microencapsulated fish oil
Bjoerlie, M.; Yesiltas, B.; Garcia-Moreno, P. J.; Espejo-Carpio, F. J.; Rahmani-Manglano, N. E.; Guadix, E. M.; Jafarpour, A.; Hansen, E. B.; Marcatili, P.; Gregersen Echers, S.; Overgaard, M. T.; Jacobsen, C.
10.1101/2022.11.18.517034 — bioengineering — Posted on 2022-11-20
1304 A direct fiber approach to model sclera collagen architecture and biomechanics
Ji, F.; Bansal, M.; Wang, B.; Hua, Y.; Islam, M. R.; Matuschke, F.; Axer, M.; Sigal, I. A.
10.1101/2022.11.20.517259 — bioengineering — Posted on 2022-11-20
1305 Phase-specific signatures of wound fibroblasts and matrix patterns define cancer-associated fibroblast subtypes
Wietecha, M. S.; Lauenstein, D.; Cangkrama, M.; Seiler, S.; Jin, J.; Goppelt, A.; Claassen, M.; Levesque, M.; Dummer, R.; Werner, S.
10.1101/2022.11.18.516967 — genomics — Posted on 2022-11-20
1309 Single-cell multi-omics reveals dynamics of purifying selection of pathogenic mitochondrial DNA across human immune cells
Lareau, C. A.; Dubois, S. M.; Buquicchio, F. A.; Hsieh, Y.-H.; Garg, K.; Kautz, P.; Nitsch, L.; Praktiknjo, S. D.; Maschmeyer, P.; Verboon, J. M.; Gutierrez, J. C.; Yin, Y.; Fiskin, E.; Luo, W.; Mimitou, E.; Muus, C.; Malhotra, R.; Parikh, S.; Fleming, M. D.; Oevermann, L.; Schulte, J.; Eckert, C.; Kundaje, A.; Smibert, P.; Satpathy, A. T.; Regev, A.; Sankaran, V. G.; Agarwal, S.; Ludwig, L. S.
10.1101/2022.11.20.517242 — genetics — Posted on 2022-11-20
1310 A novel method revealing animal evolutionary relationships based on milk Mid-infrared
Zhang, S.; Fan, Y.; Han, J.; Wang, H.; Nan, L.; Luo, X.; Chu, C.; Wang, L.; Liu, L.; Li, Y.; Li, C.; Ren, X.; Ding, L.; Liu, W.; Hao, X.; Chen, Y.; Liu, G.; Zhou, Y.
10.1101/2022.11.18.517067 — evolutionary biology — Posted on 2022-11-20
1314 Multi-site assessment of reproducibility in high-content live cell imaging data
Hu, J.; Serra-Picamal, X.; Bakker, G.-J.; Troys, M. V.; Winograd-katz, S.; Ege, N.; Gong, X.; Didan, Y.; Grosheva, I.; Polansky, O.; Bakkali, K.; Hamme, E. V.; Erp, M. v.; Vullings, M.; Weiss, F.; Clucas, J.; Dowbaj, A. M.; Sahai, E.; Ampe, C.; Geiger, B.; Friedl, P.; Bottai, M.; Stromblad, S.
10.1101/2022.11.18.516878 — cell biology — Posted on 2022-11-20
1316 Social stress induces autoimmune responses against the brain to promote stress susceptibility
Shimo, Y.; Cathomas, F.; Lin, H.-y.; Chan, K.; Parise, L. F. F.; Li, L.; Ferrer-Perez, C.; Costi, S.; Murrough, J. W.; Russo, S. J.
10.1101/2022.11.18.517081 — immunology — Posted on 2022-11-20
1323 Deep mutational scanning of essential bacterial proteins can guide antibiotic development
Dewachter, L.; Brooks, A. N.; Noon, K.; Cialek, C.; Clark-ElSayed, A.; Schalck, T.; Krishnamurthy, N.; Versees, W.; Vranken, W.; Michiels, J.
10.1101/2022.05.23.493065 — microbiology — Posted on 2022-11-20
1324 Perceptual learning improves discrimination while distorting appearance
Szpiro, S. F. A.; Burlingham, C. S.; Simoncelli, E. P.; Carrasco, M.
10.1101/2022.09.08.507104 — neuroscience — Posted on 2022-11-20
1325 In vitro and in silico analysis proving DPP4 inhibition and diabetes associated gene network modulation by a polyherbal formulation - Nisakathakadi Kashaya.
Thottappillil, A.; Sahoo, S.; Chakraborty, A.; Kouser, S.; Ravi, V.; Garawadmath, S.; Banvi, P. G.; Kukkupuni, S. K.; Mohan, S.; Chethala N, V.
10.1101/2022.07.15.500175 — systems biology — Posted on 2022-11-20
1326 Protein Language Model Predicts Mutation Pathogenicity and Clinical Prognosis
Liu, X.; Yang, X.; Ouyang, L.; Guo, G.; Su, J.; Xi, R.; Yuan, K.; Yuan, F.
10.1101/2022.09.30.510294 — bioinformatics — Posted on 2022-11-20
1329 An HBV mRNA vaccine with favorable virological suppression and superior immunity
Zhao, H.; Yu, Y.; Liu, Z.; Huang, L.; Yang, A.; Jiao, L.; Song, Z.; Wang, Y.; Bao, C.; Yu, R.; Yu, L.; Wang, G.; Wang, D.; Han, Q.; Zhang, L.; Huang, L.; Zhang, J.; Yang, Y.; Lin, A.
10.1101/2022.11.18.517095 — immunology — Posted on 2022-11-20
1331 Environmental effects on genetic variance and the alignment with plasticity and selection
Walter, G. M.; Monro, K.; Terranova, D.; la Spina, E.; Majorana, M. G.; Pepe, G.; Clark, J.; Cozzolino, S.; Cristaudo, A.; Hiscock, S. J.; Bridle, J. R.
10.1101/2021.02.08.430333 — evolutionary biology — Posted on 2022-11-20
1333 Widespread Increase in Enhancer-Promoter Interactions during Developmental Enhancer Activation in Mammals
Chen, Z.; Snetkova, V.; Bower, G.; Jacinto, S.; Clock, B.; Barozzi, I.; Mannion, B. J.; Alcaina-Caro, A.; Lopez-Rios, J.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.; Kvon, E. Z.
10.1101/2022.11.18.516017 — genomics — Posted on 2022-11-20
1334 Interferon-gamma Elicits Pathological Hallmarks of ALS in Human Motor Neurons
Chun, C.; Lee, J.; Bothwell, M.; Nghiem, P.; Smith, A. S. T.; Mack, D. L.
10.1101/2022.11.18.517141 — neuroscience — Posted on 2022-11-19
1336 Population genomics reveals mechanisms and dynamics of de novo proto-gene emergence in Drosophila melanogaster
Grandchamp, A.; Kühl, L.; Lebherz, M. K.; Brüggemann, K.; Parsch, J.; Bornberg-Bauer, E.
10.1101/2022.11.19.517182 — genomics — Posted on 2022-11-19
1337 An HBV mRNA vaccine with favorable virological suppression and superior immunity
Lin, A.; Zhao, H.; Yu, Y.; Liu, Z.; Huang, L.; Yang, A.; Jiao, L.; Song, Z.; Wang, Y.; Bao, C.; Yu, R.; Yu, L.; Wang, G.; Wang, D.; Han, Q.; Zhang, L.; Huang, L.; Zhang, J.; Yang, Y.
10.1101/2022.11.18.517095 — immunology — Posted on 2022-11-19
1338 Single cell antigen receptor analysis reveals lymphocyte developmental origins
Suo, C.; Polanski, K.; Dann, E.; Lindeboom, R. G. H.; Vilarrasa Blasi, R.; Vento-Tormo, R.; Haniffa, M.; Meyer, K. B.; Tuong, Z. K.; Clatworthy, M. R.; Teichmann, S.
10.1101/2022.11.18.517068 — immunology — Posted on 2022-11-19
1339 Sex-specific transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice
Olusakin, J.; Kumar, G.; Basu, M.; Calarco, C. A.; Fox, M. E.; Alipio, J. B.; Haga, C.; Turner, M. D.; Keller, A.; Ament, S. A.; Lobo, M. K.
10.1101/2022.11.18.517129 — neuroscience — Posted on 2022-11-19
1341 Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state
Barrett, T. F.; Patel, B.; Khan, S. M.; Yim, A. K. Y.; Pugazenthi, S.; Mahlokozera, T.; Mullins, R. D. Z.; Zipfel, G. J.; Herzog, J. A.; Chicoine, M. R.; Wick, C. C.; Durakovic, N.; Osbun, J. W.; Shew, M.; Sweeney, A. D.; Patel, A. J.; Buchman, C. A.; Petti, A. A.; Puram, S. V.; Kim, A. H.
10.1101/2022.11.18.517051 — cancer biology — Posted on 2022-11-19
1342 CryoEM Reveals Oligomeric Isomers of a Multienzyme Complex and Assembly Mechanics
Lee, J. K. J.; Liu, Y.; Hu, J. J.; Aphasizheva, I.; Aphasizhev, R.; Zhou, Z. H.
10.1101/2022.11.18.517149 — biophysics — Posted on 2022-11-19
1344 NLP-based tools for localization of the Epileptogenic Zone in patients with drug-resistant focal epilepsy
Mora, S.; Turrisi, R.; Chiarella, L.; Tassi, L.; Mai, R.; Nobili, L.; Barla, A.; Arnulfo, G.
10.1101/2022.11.18.516120 — bioengineering — Posted on 2022-11-19
1347 Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases
Cheng, X.; Barakat, R.; Gorden, A.; Snella, E.; Zhang, Y.; Dorman, K.; Fidanza, A.; Campbell, C. A.; Espin Palazon, R.
10.1101/2022.11.19.517153 — developmental biology — Posted on 2022-11-19
1349 Distinct states of nucleolar stress induced by anti-cancer drugs
Potapova, T. A.; Unruh, J. R.; Conkright-Fincham, J. J.; Banks, C. A. S.; Florens, L.; Schneider, D. A.; Gerton, J. L.
10.1101/2022.11.18.517150 — cell biology — Posted on 2022-11-19
1350 Biofilm characterization in the maize pathogen, Fusarium verticillioides
Peremore, C.; Wingfield, B.; Santana, Q.; Steenkamp, E.; Motaung, T. E.
10.1101/2022.11.18.517162 — microbiology — Posted on 2022-11-19
1355 Cell-free biosynthesis combined with deep learning accelerates de novo-development of antimicrobial peptides
Pandi, A.; Adam, D.; Zare, A.; Trinh, V. T.; Schaefer, S. L.; Wiegand, M.; Klabunde, B.; Bobkova, E.; Kushwaha, M.; Foroughijabbari, Y.; Braun, P.; Spahn, C.; Preusser, C.; von Strandmann, E. P.; Bode, H. B.; von Buttlar, H.; Bertrams, W.; Jung, A. L.; Abendroth, F.; Schmeck, B.; Hummer, G.; Vazquez, O.; Erb, T. J.
10.1101/2022.11.19.517184 — synthetic biology — Posted on 2022-11-19
1356 Accurate Computational Design of 3D Protein Crystals
Li, Z.; Wang, S.; Nattermann, U.; Bera, A. K.; Borst, A. J.; Bick, M. J.; Yang, E. C.; Sheffler, W.; Lee, B.; Seifert, S.; Nguyen, H.; Kang, A.; Dalal, R.; Lubner, J. M.; Hsia, Y.; Haddox, H.; Courbet, A. P.; Dowling, Q.; Miranda, M.; Favor, A.; Etemadi, A.; Edman, N. I.; Yang, W.; Sankaran, B.; Negahdari, B.; Baker, D.
10.1101/2022.11.18.517014 — synthetic biology — Posted on 2022-11-19
1357 Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries
Misek, S. A.; Fultineer, A.; Kalfon, J.; Noorbakhsh, J.; Boyle, I.; Dempster, J.; Petronio, L.; Huang, K.; Saadat, A.; Green, T.; Brown, A.; Doench, J. G.; Root, D. E.; McFarland, J.; Beroukhim, R.; Boehm, J. S.
10.1101/2022.11.18.517155 — cancer biology — Posted on 2022-11-19
1358 Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation
Han, L.; Wu, X.; Wang, O.; Velander, W. H.; Aynardi, M.; Halstead, E. S.; Li, Y.; Wang, Y.; Dong, C.; Lei, Y.
10.1101/2022.11.19.517148 — bioengineering — Posted on 2022-11-19
1359 Targeted degradation of PRC1 components, BMI1 and RING1B, via a novel protein complex degrader strategy
Park, K.-S.; Qin, L.; Kabir, M.; Luo, K.; Dale, B.; Zhong, Y.; Kim, A.; Wang, G.; Kaniskan, H. U.; Jin, J.
10.1101/2022.11.19.517138 — biochemistry — Posted on 2022-11-19
1362 Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate
Ruettermann, M.; Koci, M.; Lill, P.; Klink, B. U.; Erdmann, R.; Gatsogiannis, C.
10.1101/2022.11.19.517173 — molecular biology — Posted on 2022-11-19
1365 Effect of biomaterial stiffness on cardiac mechanics in a biventricular infarcted rat heart model with microstructural representation of in situ intramyocardial injectate
Motchon, Y. D.; Sack, K. L.; Sirry, M. S.; Kruger, M.; Pauwels, E.; Van Loo, D.; De Muynck, A.; Van Hoorebeke, L.; Davies, N. H.; Franz, T.
10.1101/2022.05.23.493036 — biophysics — Posted on 2022-11-19
1367 2-hydroxyglutarate controls centromere and heterochromatin conformation and function in the male germline
Mayorek, N.; Schlossberg, M.; Mansour, Y.; Pillar, N.; Stein, I.; Mushasha, F.; Baziza, G.; Medvedev, E.; Manevitch, Z.; Menzel, J.; Aizenshtein, E.; Sarvin, B.; Sarvin, N.; Shlomi, T.; Klutstein, M.; Pikarsky, E.
10.1101/2022.05.29.493890 — cell biology — Posted on 2022-11-19
1369 The use of non-functional clonotypes as a natural calibrator for multiplex PCR bias correction in adaptive immune receptor repertoire profiling
Smirnova, A. O.; Miroshnichenkova, A. M.; Olshanskaya, Y. V.; Maschan, M. A.; Lebedev, Y. B.; Chudakov, D. M.; Mamedov, I.; Komkov, A. Y.
10.1101/2021.03.24.436794 — immunology — Posted on 2022-11-19
1371 Wenzhou shrimp virus 8 (WzSV8) detection by unique inclusions in shrimp hepatopancreatic E-cellsand by RT-PCR
Srisala, J.; Thaiue, D.; Saguanrut, P.; Taengchaiyaphum, S.; Flegel, T. W.; Sritunyalucksana, K.
10.1101/2022.08.15.504032 — zoology — Posted on 2022-11-19
1374 The Impact of Colistin Resistance on the Activation of Innate Immunity by Lipopolysaccharide Modification
Avendano-Ortiz, J.; Ponce-Alonso, M.; Llanos-Gonzalez, E.; Barragan-Praga, H.; Ballestero, L.; Lozano-Rodriguez, R.; Marquez-Garrido, F. J.; Hernandez-Perez, J. M.; Morosini, M. I.; Canton, R.; del Campo, R.; Lopez-Collazo, E.
10.1101/2022.11.17.517013 — microbiology — Posted on 2022-11-19
1375 Running ahead of evolution - AI based simulation for predicting future high-risk SARS-CoV-2 variants
Chen, J.; Nie, Z.; Wang, Y.; Wang, K.; Xu, F.; Hu, Z.; Zheng, B.; Wang, Z.; Song, G.; Zhang, J.; Fu, J.; Huang, X.; Wang, Z.; Ren, Z.; Wang, Q.; Li, D.; Wei, D.; zhou, B.; Yang, C.; Tian, Y.
10.1101/2022.11.17.516989 — bioinformatics — Posted on 2022-11-19
1378 CD90 is not constitutively expressed in functional innate lymphoid cells
Schroeder, J.-H.; Beattie, G.; Lo, J. W.; Zabinski, T.; Jenner, R.; Powell, N.; Neves, J. F.; Lord, G. M.
10.1101/2021.12.11.472210 — immunology — Posted on 2022-11-19
1381 Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations
Kafkova, A.; Tilokani, L.; Trcka, F.; Sramkova, V.; Vancova, M.; Bily, T.; Nebesarova, J.; Prudent, J.; Trnka, J.
10.1101/2021.03.09.434520 — biochemistry — Posted on 2022-11-19
1382 Transcription shapes 3D chromatin organization by interacting with loop extrusion
Banigan, E. J.; Tang, W.; van den Berg, A. A.; Stocsits, R. R.; Wutz, G.; Brandao, H. B.; Busslinger, G. A.; Peters, J.-M.; Mirny, L. A.
10.1101/2022.01.07.475367 — genomics — Posted on 2022-11-18
1385 Transcriptomically unique endolysosomal and homeostatic microglia populations in Alzheimer's disease and aged human brain
Prater, K. E.; Green, K. J.; Mamde, S.; Sun, W.; Cochoit, A.; Smith, C.; Chiou, K. L.; Heath, L. M.; Rose, S.; Wiley, J.; Keene, C. D.; Kwon, R. Y.; Snyder-Mackler, N.; Blue, E.; Logsdon, B.; Young, J. E.; Shojaie, A.; Garden, G. A.; Jayadev, S.
10.1101/2021.10.25.465802 — neuroscience — Posted on 2022-11-18
1386 Neonatal brain dynamic functional connectivity: impact of preterm birth and association with early childhood neurodevelopment
Franca, L. G. S.; Ciarrusta, J.; Gale-Grant, O.; Fenn-Moltu, S.; Fitzgibbon, S. P.; Chew, A.; Falconer, S.; Dimitrova, R.; Cordero-Grande, L.; Price, A. N.; Hughes, E.; O'Muircheartaigh, J.; Duff, E.; Tuulari, J. J.; Deco, G.; Counsell, S. J.; Hajnal, J. V.; Nosarti, C.; Arichi, T.; Edwards, D.; McAlonan, G.; Batalle, D.
10.1101/2022.11.16.516610 — neuroscience — Posted on 2022-11-18
1387 Lipid hydroperoxides promote sarcopenia through carbonyl stress
Eshima, H.; Shahtout, J. L.; Siripoksup, P.; Pearson, M. J.; Mahmassani, Z. S.; Ferrara, P. J.; Lyons, A. W.; Maschek, J. A.; Peterlin, A. D.; Verkerke, A. R. P.; Johnson, J. M.; Salcedo, A.; Petrocelli, J. J.; Miranda, E. R.; Anderson, E. J.; Boudina, S.; Ran, Q.; Cox, J. E.; Drummond, M. J.; Funai, K.
10.1101/2021.12.17.473200 — physiology — Posted on 2022-11-18
1389 Truncated Caveolin-3 Mutation In Familial Barretts Esophagus
Garman, K. S.; von Furstenberg, R.; Fecteau, R.; Becker, T. C.; Purkayastha, B.; Falk, G. W.; Dawson, D.; Willis, J. E.; McCall, S.; Blum, A.; Guda, K.; Chak, A.
10.1101/2021.05.15.444305 — cancer biology — Posted on 2022-11-18
1390 Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins
Pesce, F.; Newcombe, E. A.; Seiffert, P.; Tranchant, E. E.; Olsen, J. G.; Grace, C. R.; Kragelund, B. B.; Lindorff-Larsen, K.
10.1101/2022.06.11.495732 — biophysics — Posted on 2022-11-18
1391 Causal identification of single-cell experimental perturbation effects with CINEMA-OT
Dong, M.; Wang, B.; Wei, J.; Perry, C.; Frey, A.; Ouerghi, F.; Foxman, E. F.; Ishizuka, J. J.; Dhodapkar, R. M.; van Dijk, D.
10.1101/2022.07.31.502173 — bioinformatics — Posted on 2022-11-18
1394 Four decades of phenology in an alpine amphibian: trends, stasis, and climatic drivers
Lenzi, O.; Grossenbacher, K.; Zumbach, S.; Luescher, B.; Althaus, S.; Schmocker, D.; Recher, H.; Thoma, M.; Ozgul, A.; Schmidt, B. R.
10.1101/2022.08.16.503739 — ecology — Posted on 2022-11-18
1395 Low-level repressive histone marks fine-tune stemness gene transcription in neural stem cells
Rajan, A.; Anhezini, L.; Rives-Quinto, N.; Neville, M. C.; Larson, E. D.; Goodwin, S.; Harrison, M. M.; Lee, C.-Y.
10.1101/2022.11.18.517130 — developmental biology — Posted on 2022-11-18
1396 Endocytosis in Trypanosoma cruzi Depends on Proper Recruitment and Regulation of Functionally Redundant Myosin Motors
Chasen, N. M.; Etheridge, M. G.; Campbell, P. C.; de Graffenried, C. L.; Bimpeh, K.; Hines, K. M.; Etheridge, R. D.
10.1101/2022.11.17.517012 — microbiology — Posted on 2022-11-18
1397 Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal.
Rieskamp, J. D.; Rosado-Burgos, I.; Christofi, J. E.; Ansar, E.; Einstein, D.; Walters, A. E.; Valentini, V.; Bruno, J. P.; Kirby, E. D.
10.1101/2022.10.31.514562 — neuroscience — Posted on 2022-11-18
1400 Commitment in the Pink1/Parkin mitophagy decision circuit
Waters, C. S.; Angenent, S. B.; Altschuler, S. J.; Wu, L. F.
10.1101/2022.10.07.510659 — systems biology — Posted on 2022-11-18
1403 Denoising physiological data collected during multi-band, multi-echo EPI sequences
Bottenhorn, K. L.; Salo, T.; Riedel, M. C.; Sutherland, M. T.; Robinson, J. L.; Musser, E. D.; Laird, A. R.
10.1101/2021.04.01.437293 — physiology — Posted on 2022-11-18
1406 HiTaC: Hierarchical Taxonomic Classification of Fungal ITS Sequences
Miranda, F. M.; Azevedo, V. A. C.; Renard, B. Y.; C. Piro, V.; Ramos, R. T. J.
10.1101/2020.04.24.014852 — bioinformatics — Posted on 2022-11-18
1408 Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma
Resztak, J.; Choe, J.; Wei, J.; Bruinsma, R.; Houpt, R.; Alazizi, A.; Mair-Meijers, H.; Wen, X.; Slatcher, R.; Zilioli, S.; Pique-Regi, R.; Luca, F.
10.1101/2021.11.24.469939 — genomics — Posted on 2022-11-18
1409 Integrating opportunistic and structured non-invasive surveys with spatial capture-recapture models to map connectivity of the Pyrenean brown bear population
Kervellec, M.; Milleret, C.; Vanpe, C.; Quenette, P.-Y.; Sentilles, J.; Palazon, S.; Jordana, I. A.; Jato, R.; Elosegui Irurtia, M. M.; Gimenez, O.
10.1101/2022.05.13.491807 — ecology — Posted on 2022-11-18
1411 Plant pathogenic Ralstonia phylotypes evolved divergent respiratory strategies and behaviors to thrive in xylem
Truchon, A. N.; Dalsing, B. L.; Khokhani, D.; MacIntyre, A.; McDonald, B. R.; Ailloud, F.; Klassen, J.; Gonzalez-Orta, E. T.; Currie, C.; Prior, P.; Lowe-Power, T. M.; Allen, C.
10.1101/2022.11.09.515861 — microbiology — Posted on 2022-11-18
1412 Multi-scale structural alterations of the thalamus and basal ganglia in focal epilepsy as demonstrated by 7T MRI
Haast, R. A.; Testud, B.; Makhalova, J.; Dary, H.; Cabane, A.; Le Troter, A.; Ranjeva, J.-P.; Bartolomei, F.; Guye, M.
10.1101/2022.11.01.514655 — neuroscience — Posted on 2022-11-18
1415 Activity-dependent lateral inhibition signals for synaptic competition
Fujimoto, S.; Leiwe, M. N.; Aihara, S.; Sakaguchi, R.; Muroyama, Y.; Kobayakawa, R.; Kobayakawa, K.; Saito, T.; Imai, T.
10.1101/625616 — neuroscience — Posted on 2022-11-18
1416 Hub types and their translational actions in research meetings: a conversation analytic approach
Bet, M. D. A.; Antvelink, A. R.; van der Burgt, S. M. E.; Peerdeman, S. M.; Geurts, J. J. G.; Lamerichs, J. M. W. J.; Douw, L.
10.1101/2022.11.15.516566 — scientific communication and education — Posted on 2022-11-18
1417 Sodium regulates PLC and IP3R-mediated calcium signalling in invasive breast cancer cells
James, A. D.; Unthank, K. P.; Jones, I.; Sajjaboontawee, N.; Sizer, R. E.; Chawla, S.; Evans, G. J. O.; Brackenbury, W. J.
10.1101/2022.08.10.503447 — cancer biology — Posted on 2022-11-18
1419 A multi-scale transcriptional regulatory network knowledge base for Escherichia coli
Lamoureux, C. R.; Decker, K. T.; Sastry, A. V.; Rychel, K.; Gao, Y.; McConn, J. L.; Zielinski, D. C.; Palsson, B. O.
10.1101/2021.04.08.439047 — bioinformatics — Posted on 2022-11-18
1434 PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven adaptive resistance
Wong, C. W.; Evangelou, C.; Sefton, K. N.; Leshem, R.; Sergiou, K.; Fernandez Carro, M. L.; Uzuner, E.; Mole, H.; Telfer, B. A.; Wilcock, D. J.; Smith, M. P.; Kunii, K.; Perl, N. R.; Lorigan, P.; Williams, K. J.; Rao, P. E.; Nagaraju, R. T.; Niepel, M.; Hurlstone, A. F. L.
10.1101/2022.11.18.517143 — cancer biology — Posted on 2022-11-18
1437 Characterizing a century of genetic diversity and contemporary antigenic diversity of N1 neuraminidase in IAV from North American swine
Hufnagel, D. E.; Young, K. M.; Arendsee, Z.; Gay, L. C.; Caceres, C. J.; Rajao, D. S.; Perez, D. R.; Vincent Baker, A. L.; Anderson, T. K.
10.1101/2022.11.18.517097 — evolutionary biology — Posted on 2022-11-18
1438 The Response of the Eukaryotic Replisome to G-quadruplex- and i-motif-forming Sequences
Williams, S. L.; Casas-Delucchi, C. S.; Raguseo, F.; Guneri, D.; Minamino, M.; Fletcher, E. E.; Yeeles, J. T.; Waller, Z. A.; Di Antonio, M.; Coster, G.
10.1101/2022.11.18.517070 — molecular biology — Posted on 2022-11-18
1442 A NEW VARIANT OF HEPATITIS A VIRUS CAUSING TRANSIENT LIVER ENZYME ELEVATIONS IN MAURITIUS-ORIGIN LABORATORY-HOUSED CYNOMOLGUS MACAQUES
Mecklenburg, L.; Ducore, R.; Boyle, M.; Newell, A.; Boone, L.; Luft, J.; Romeike, A.; Haverkamp, A.-K.; Mansfield, K.; Baczenas, J.; Minor, N.; O'Connor, S. L.; O'Connor, D. H.
10.1101/2022.11.18.515766 — microbiology — Posted on 2022-11-18
1444 CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages
Mohamed, S. H.; Vonhoffelen, E.; Fu, M. S.; Cosway, E.; Anderson, G.; Vande Velde, G.; Drummond, R. A.
10.1101/2022.11.18.517077 — immunology — Posted on 2022-11-18
1445 Antagonism between viral infection and innate immunity at the single-cell level
Grabowski, F.; Kochanczyk, M.; Korwek, Z.; Czerkies, M.; Prus, W.; Lipniacki, T.
10.1101/2022.11.18.517110 — systems biology — Posted on 2022-11-18
1450 Overexpression of PSR1 in Chlamydomonas reinhardtii induces luxury phosphorus uptake
Slocombe, S. P.; Burgos, T. Z.; Chu, L.; Mehrshahi, P.; Davey, M. P.; Smith, A. G.; Camargo-Valero, M. A.; Baker, A.
10.1101/2022.11.18.517064 — bioengineering — Posted on 2022-11-18
1452 Accelerating crystal structure determination with iterative AlphaFold prediction
Terwilliger, T. C.; Afonine, P. V.; Liebschner, D.; Croll, T. I.; McCoy, A. J.; Oeffner, R. D.; Williams, C. J.; Poon, B. K.; Richardson, J. S.; Read, R. J.; Adams, P. D.
10.1101/2022.11.18.517112 — biochemistry — Posted on 2022-11-18
1453 Endocrine disruption of early uterine differentiation causes adenocarcinoma mediated by Wnt/β-catenin- and PI3K/AKT signaling
Padilla-Banks, E.; Jefferson, W. N.; Papas, B. N.; Suen, A. A.; Xu, X.; Carreon, D. V.; Willson, C. J.; Quist, E. M.; Williams, C. J.
10.1101/2022.11.18.517135 — developmental biology — Posted on 2022-11-18
1454 Streptomyces alleviate abiotic stress in plant by producing pteridic acids
Yang, Z.; Stroebech, E.; Qiao, Y.; Konakalla, N. C.; Harris, P.; Peschel, G.; Rosenbaum, M.; Weber, T.; Andreasson, E.; Ding, L.
10.1101/2022.11.18.517137 — microbiology — Posted on 2022-11-18
1455 In silico docking screen identifies airway host protease targets for human SERPINs
Rodriguez Galvan, J. J.; de Vries, M.; Fisher, A.; Prescott, R. A.; Crosse, K. M.; Duerr, R.; Dittmann, M.
10.1101/2022.11.18.517133 — microbiology — Posted on 2022-11-18
1456 Distinct super-enhancer elements differentially control Il2ra gene expression in a cell-type specific fashion
Spolski, R.; Li, P.; Chandra, V.; Shin, B.; Liu, C.; Oh, J.; Ren, M.; Enomoto, Y.; West, E. E.; Christensen, S.; Wan, E. C. K.; Ge, M.; Lin, J.-X.; Vijayanand, P.; Rothenberg, E. V.; Leonard, W. J.
10.1101/2022.11.18.516445 — immunology — Posted on 2022-11-18
1459 Deducing ensemble dynamics and information flow from the whole-brain imaging data
Toyoshima, Y.; Sato, H.; Nagata, D.; Kanamori, M.; Jang, M. S.; Kuze, K.; Oe, S.; Teramoto, T.; Iwasaki, Y.; Yoshida, R.; Ishihara, T.; Iino, Y.
10.1101/2022.11.18.517011 — neuroscience — Posted on 2022-11-18
1462 Steroidogenesis and androgen/estrogen signaling pathways are altered in in vitro matured testicular tissues of prepubertal mice
Moutard, L.; Goudin, C.; Jaeger, C.; Duparc, C.; Louiset, E.; Pereira, T.; Fraissinet, F.; Delessard, M.; Saulnier, J.; Rives-Feraille, A.; Delalande, C.; Lefebvre, H.; Rives, N.; Dumont, L.; Rondanino, C.
10.1101/2022.11.18.517042 — developmental biology — Posted on 2022-11-18
1465 Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons
MOREAU, M. X.; SAILLOUR, Y.; ELLORIAGA, V.; BOULOUDI, B.; DELBERGHE, E.; DEUTSCH GUERRERO, T.; OCHANDORENA-SAA, A.; MAESO-ALONSO, L.; MARQUES, M. M.; MARIN, M. C.; SPASSKY, N.; PIERANI, A.; CAUSERET, F.
10.1101/2022.11.18.517020 — developmental biology — Posted on 2022-11-18
1466 Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis
Mota-Gomez, I.; Rodriguez, J. A.; Dupont, S.; Lao, O.; Jedamzick, J.; Kuhn, R.; Lacadie, S.; Garcia-Moreno, S. A.; Hurtado, A.; Acemel, R. D.; Capel, B.; Marti-Renom, M. A.; Lupianez, D. G.
10.1101/2022.11.18.516861 — developmental biology — Posted on 2022-11-18
1469 Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer's Disease
Daniels, M. J. D.; Lefevre, L.; Drake, A.; Szymkowiak, S.; McCulloch, L.; Tzioras, M.; Barrington, J.; Dando, O. R.; He, X.; Mohammad, M.; Sasaguri, H.; Saito, T.; Saido, T. C.; Spires-Jones, T. L.; McColl, B. W.
10.1101/2022.11.18.516922 — neuroscience — Posted on 2022-11-18
1470 Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation
Park, E.; Kao, H.-Y.; Jourdi, H.; van Dijk, M.; Carrillo-Segura, S.; Tunnell, K. W.; Gutierrez, J.; Wallace, E. J.; Troy-Regier, M.; Radwan, B.; Lesburgueres, E.; Alarcon, J. M.; Fenton, A. A.
10.1101/2022.11.18.517075 — neuroscience — Posted on 2022-11-18
1471 Subcellular proteome of radial glia reveals non-muscle myosins control basal endfeet to mediate interneuron organization
D'Arcy, B.; Lennox, A.; Manso Musso, C.; Bracher, A.; Escobar-Tomlienovich, C.; Perez-Sanchez, S.; Silver, D. L.
10.1101/2022.11.18.517018 — neuroscience — Posted on 2022-11-18
1477 Human Early Syncytiotrophoblasts Are Highly Susceptible to SARS-CoV-2 Infection
Liu, P.; RUAN, D.; Ye, Z.-W.; Yuan, S.; Li, Z.; Zhang, W.; Ong, C. P.; Tang, K.; Guo, J.; Xuan, Y.; Tam, T. T. K. K.; Huang, Y.; Zhang, Q.; Lee, C.-L.; Chiu, P. C. N.; Liu, F.; Jin, D.-Y.
10.1101/2022.11.17.516978 — cell biology — Posted on 2022-11-18
1478 Endocytosis in Trypanosoma cruzi Depends on Proper Recruitment and Regulation of Functionally Redundant Myosin Motors
Chasen, N. M.; Etheridge, M. G.; Campbell, P. C.; de Graffenried, C. L.; Bimpeh, K.; Hines, K. M.; Etheridge, R. D.
10.1101/2022.11.17.517012 — microbiology — Posted on 2022-11-18
1479 Innate immune response to SARS-1 CoV-2 infection contributes to neuronal damage in human iPSC-derived peripheral neurons
Passos, V.; Henkel, L. M.; Wang, J.; Zapatero-Belinchon, F. J.; Moeller, R.; Sun, G.; Waltl, I.; Ritter, B.; Kropp, K. A.; Zhu, S.; Deleidi, M.; Kalinke, U.; Hoeglinger, G.; Gerold, G.; Wegner, F.; Viejo-Borbolla, A.
10.1101/2022.11.18.517047 — microbiology — Posted on 2022-11-18
1481 Rising SARS-CoV-2 Seroprevalence and Patterns of Cross-Variant Antibody Neutralization in UK Domestic Cats
Tyson, G. B.; Jones, S.; Logan, N.; McDonald, M.; Murcia, P. R.; Willett, B. J.; Weir, W.; Hosie, M. J.
10.1101/2022.11.18.517046 — immunology — Posted on 2022-11-18
1482 A novel fishing cat reference genome for the evaluation of potential germline risk variants
Carroll, R. A.; Rice, E. S.; Murphy, W. J.; Lyons, L. A.; Coghill, L. M.; Swanson, W. F.; Terio, K. A.; Boyd, T.; Warren, W. C.
10.1101/2022.11.17.516921 — zoology — Posted on 2022-11-18
1484 In silico network-based screening reveals candidates for endothelial dysfunction therapy
Pinheiro-de-Sousa, I.; Giudice, G.; Fonseca-Alaniz, M. H.; Modestia, S. M.; Mattioli, S. V.; Fang, Y.; Petsalaki, E.; Krieger, J. E.
10.1101/2022.11.17.516953 — systems biology — Posted on 2022-11-18
1486 Deconvolution of plasma pharmacokinetics from dynamic heart imaging data obtained by SPECT/CT imaging
Wang, Z.; Wang, L.; Ebbini, M.; Curran, G. L.; Min, P. H.; Siegel, R. A.; Lowe, V. J.; Kandimalla, K. K.
10.1101/2022.11.17.517003 — pharmacology and toxicology — Posted on 2022-11-18
1487 Hamsters are a model for COVID-19 alveolar regeneration mechanisms: an opportunity to understand post-acute sequelae of SARS-CoV-2
Heydemann, L.; Ciurkiewicz, M.; Beythien, G.; Becker, K.; Schughart, K.; Stanelle-Bertram, S.; Schaumburg, B.; Mounogou-Kouassi, N.; Beck, S.; Zickler, M.; Kuehnel, M.; Gabriel, G.; Beineke, A.; Baumgaertner, W.; Armando, F.
10.1101/2022.11.17.515635 — pathology — Posted on 2022-11-18
1491 Cellular Maturation of Oligodendrocytes is Governed by Transient Gene Melting
Allan, K. C.; Miller, T. E.; Morton, A. R.; Scavuzzo, M. A.; Elitt, M. S.; Clayton, B. L.; Hu, L. R.; Vrabic, J. K.; Olsen, H. E.; Factor, D. C.; Henninger, J. E.; Young, R. A.; Lin, C. Y.; Scacheri, P. C.; Tesar, P. J.
10.1101/2022.11.17.516981 — developmental biology — Posted on 2022-11-18
1492 Evolutionarily conserved waves of tooth replacement in the gecko are dependent on local signaling
Brink, K. S.; Cytrynbaum, E. N.; Grieco, T. M.; Henriquez, J. I.; Zhitnitsky, A.; Richman, J. M.
10.1101/2022.11.17.513312 — developmental biology — Posted on 2022-11-18
1493 Rab11 is essential to pancreas morphogenesis, lumen formation and endocrine mass.
Barlow, H. R.; Htike, Y.; Fassetta, L.; Ahuja, N.; Bierschenk, T.; Azizoglu, D. B.; Flores, J.; Gao, N.; Marciano, D.; Cleaver, O.
10.1101/2022.11.17.516976 — developmental biology — Posted on 2022-11-18
1494 Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that comprise distinct phasevarions
Nahar, N.; Tram, G.; Jen, F. E.- C.; Phillips, Z. N.; Weinert, L.; Bosse, J.; Jabbari, J.; Gouil, Q.; Du, M.; Ritchie, M. E.; Bowden, R.; Langford, P. R.; Tucker, A. W.; Jennings, M. P.; Turni, C.; Blackall, P. J.; Atack, J. M.
10.1101/2022.11.17.516983 — microbiology — Posted on 2022-11-18
1499 Statistically unbiased prediction enables accurate denoising of voltage imaging data
Eom, M.; Han, S.; Kim, G.; Cho, E.-S.; Sim, J.; Park, P.; Lee, K.-H.; Kim, S.; Rozsa, M.; Svoboda, K.; Choi, M.; Kim, C.-H.; Cohen, A.; Chang, J.-B.; Yoon, Y.-G.
10.1101/2022.11.17.516709 — neuroscience — Posted on 2022-11-18
1504 Esr1+ hypothalamic-habenula neurons shape aversive states.
Calvigioni, D.; Fuzik, J.; Le Merre, P.; Slashcheva, M.; Jung, F.; Ortiz, C.; Lentini, A.; Csillag, V.; Graziano, M.; Nikolakopoulou, I.; Weglage, M.; Lazaridis, I.; Kim, H.; Lenzi, L.; Park, H.; Reinius, B.; Carlen, M.; Meletis, K.
10.1101/2022.11.17.516965 — neuroscience — Posted on 2022-11-18
1511 Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways
Pun, M.; Pratt, D.; Nano, P. R.; Joshi, P. K.; Jiang, L.; Englinger, B.; Rao, A.; Cieslik, M.; Chinnaiyan, A. M.; Aldape, K.; Pfister, S.; Filbin, M.; Bhaduri, A.; Venneti, S.
10.1101/2022.11.17.516833 — cancer biology — Posted on 2022-11-18
1512 Collective gradient sensing by swimming bacteria without clustering
Kai, T.; Abe, T.; Yoshinaga, N.; Nakamura, S.; Kudo, S.; Toyabe, S.
10.1101/2022.11.17.516991 — biophysics — Posted on 2022-11-18
1513 Inferring ligand-receptor cellular networks from bulk and spatial transcriptomic datasets with BulkSignalR
VILLEMIN, J.-P.; Bassaganyas, L.; Pourquier, D.; Boissiere, F.; Cabello-Aguilar, S.; Crapez, E.; Tanos, R.; Cornillot, E.; Turtoi, A.; Colinge, J.
10.1101/2022.11.17.516911 — bioinformatics — Posted on 2022-11-18
1514 PlantTribes2: tools for comparative gene family analysis in plant genomics
Wafula, E. K.; Zhang, H.; Kuster, G. V.; Leebens-Mack, J.; Honaas, L.; dePamphilis, C.
10.1101/2022.11.17.516924 — bioinformatics — Posted on 2022-11-18
1516 Integrated single cell analysis reveals co-evolution of malignant B cells and the tumor microenvironment in transformed follicular lymphoma
Sarkozy, C.; Wu, S.; Takata, K.; Aoki, T.; Neriah, S. B.; Milne, K.; Goodyear, T.; Strong, C.; Rastogi, T.; Lai, D.; Sehn, L. H.; Farinha, P.; Nelson, B. H.; Weng, A.; Scott, D. W.; Craig, J. W.; Steidl, C.; Roth, A.
10.1101/2022.11.17.516951 — bioinformatics — Posted on 2022-11-18
1521 ppGpp is Present in and Functions to Regulate Sleep in Drosophila
Dai, X.; Yang, W.; Zhang, X.; Zhou, E.; Liu, Y.; Wang, T. V.; Zhang, W.; Zhang, X.; Rao, Y.
10.1101/2022.11.17.516975 — genetics — Posted on 2022-11-18
1523 Association of spinocerebellar ataxia related variants with myokymia and neuromyotonia in dogs
Vanhaesebrouck, A.; Van Poucke, M.; Stee, K.; Peelman, L.; Van Ham, L.; Bhatti, S. F.
10.1101/2022.11.17.516927 — genetics — Posted on 2022-11-18
1524 Linking movement and dive data to prey distribution models: new insights in foraging behaviour and potential pitfalls of movement analyses
Florko, K. R.; Shuert, C. R.; Cheung, W. W.; Ferguson, S.; Jonsen, I. D.; Rosen, D. A.; Sumaila, U. R.; Tai, T. C.; Yurkowski, D. J.; Auger-Methe, M.
10.1101/2022.11.17.516808 — ecology — Posted on 2022-11-18
1525 Evaluation of Renal Markers in Systemic Autoimmune Diseases
Krishnamurthy, H.; Yang, Y.; Song, Q.; Krishna, K.; Jayaraman, V.; Wang, T.; Bei, K.; Rajasekaran, J. J.
10.1101/2022.11.17.516932 — immunology — Posted on 2022-11-18
1527 Sleep deprivation measured by voice analysis
Thoret, E.; Andrillon, T.; Gauriau, C.; Leger, D.; Pressnitzer, D.
10.1101/2022.11.17.516913 — neuroscience — Posted on 2022-11-18
1528 Callosal inputs generate side-invariant receptive fields in the barrel cortex
Montanari, R.; Alonso-Andres, A.; Cabrera-Moreno, J.; Alegre-Cortes, J.; Reig, R.
10.1101/2022.11.17.516910 — neuroscience — Posted on 2022-11-18
1535 The central role of pyruvate metabolism on the epigenetic and molecular maturation of bovine cumulus-oocytes complexes.
Alcantara da Silva, J. V.; Ispada, J.; Junior, A. M. d. F.; Bruna de Lima, C.; dos Santos, E.; Chiaratti, M.; Perecin Nociti, R.; Milazzotto, M. P.
10.1101/2022.11.17.516185 — molecular biology — Posted on 2022-11-18
1536 Hypothalamic vasopressin sex differentiation is established during embryonic neurogenesis
Zheng, J.; Moazen, P.; Baimoukhametova, D.; Lebel, C.; Bains, J. S.; Kurrasch, D.
10.1101/2022.11.17.516788 — neuroscience — Posted on 2022-11-18
1538 3D reconstruction of ultra-high resolution neurotransmitter receptor atlases in human and non-human primate brains
Funck, T.; Wagstyl, K.; Lepage, C.; Omidyeganeh, M.; Toussaint, P. J.; Amunts, K.; Thiel, A.; Palomero-Gallagher, N.; Evans, A. C.
10.1101/2022.11.18.517039 — neuroscience — Posted on 2022-11-18
1539 The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
Stewart, H.; Lu, Y.; O'Keefe, S.; Valpadashi, A.; Cruz-Zaragoza, L. D.; Michel, H. A.; Nguyen, S. K.; Carnell, G. W.; Lukhovitskaya, N.; Milligan, R.; Jungreis, I.; Lulla, V.; Davidson, A. D.; Matthews, D. A.; High, S.; Rehling, P.; Emmott, E.; Heeney, J. L.; Edgar, J. R.; Smith, G. L.; Firth, A. E.
10.1101/2022.11.15.516323 — microbiology — Posted on 2022-11-18
1541 Factors associated with adherence to annual rabies vaccination in dogs and cats in the municipality of Curuca, Eastern Amazon
de Andrade, E. A.; Nascimento, K. K. G.; Silva, M. B.; Morais, J. V.; Carneiro, M. J. C.; Monteiro, M. V.; Azevedo, C. F.; Rocha, C. M. B.; Chaves, L. B.; Scheffer, K. C.; Cunha-Neto, R. d. S.; Abel, I.
10.1101/2022.11.15.516558 — scientific communication and education — Posted on 2022-11-18
1546 Dietary fibre controls blood pressure and cardiovascular risk by lowering large intestinal pH and activating the proton-sensing receptor GPR65
Xie, L.; Rhys-Jones, D.; Muralitharan, R. R.; Dinakis, E.; Nakai, M.; Paterson, M.; Peh, A.; Jama, H.; Salimova, E.; Anderson, D.; Ang, C.; Alam, M. J.; Yap, Y.-A.; Creek, D.; Robert, R.; Yao, C.; So, D.; Head, G.; Gibson, P. R.; Muir, J.; O'Donnell, J.; Mackay, C. R.; Marques, F. Z.
10.1101/2022.11.17.516695 — molecular biology — Posted on 2022-11-18
1547 Hippocampal-cortical functional connectivity during memory encoding and retrieval
Raud, L.; Sneve, M. H.; Vidal-Pineiro, D.; Sorensen, O.; Folvik, L.; Ness, H. T.; Mowinckel, A. M.; Grydeland, H.; Walhovd, K. B.; Fjell, A. M.
10.1101/2022.09.02.506311 — neuroscience — Posted on 2022-11-18
1548 Arabidopsis pollen Prolyl-hydroxylases P4H4/6 are required for correct hydroxylation and secretion of LRX11 in pollen tubes
Sede, A. R.; Wengier, D. L.; Borassi, C.; Ricardi, M.; Somoza, S. C.; Aguilo, R.; Estevez, J.; Muschietti, J. P.
10.1101/2022.11.16.516804 — plant biology — Posted on 2022-11-18
1551 ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development
Graham-Paquin, A.-L.; Saini, D.; Sirois, J.; Hossain, I.; Katz, M. S.; Zhuang, Q. K.-W.; Kwon, S. Y.; Yamanaka, Y. A.; Bourque, G.; Bouchard, M.; Pastor, W. A.
10.1101/2022.09.13.507699 — molecular biology — Posted on 2022-11-18
1556 Strategic self-control of arousal boosts sustained attention
de Gee, J. W.; Mridha, Z.; Hudson, M.; Shi, Y.; Ramsaywak, H.; Smith, S.; Karediya, N.; Thompson, M.; Jaspe, K.; Zhang, W.; McGinley, M. J.
10.1101/2022.03.04.482962 — neuroscience — Posted on 2022-11-18
1557 Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance
Huang, J.; Tao, H.; Yancey, P. G.; Leuthner, Z.; May-Zhang, L.; Jung, J.-Y.; Zhang, Y.; Ding, L.; Amarnath, V.; Liu, D.; Collins, S.; Davies, S. S.; Linton, M. F.
10.1101/529339 — pharmacology and toxicology — Posted on 2022-11-18
1560 Neonatal brain dynamic functional connectivity: impact of preterm birth and association with early childhood neurodevelopment
Franca, L. G. S.; Ciarrusta, J.; Gale-Grant, O.; Fenn-Moltu, S.; Fitzgibbon, S. P.; Chew, A.; Falconer, S.; Dimitrova, R.; Cordero-Grande, L.; Price, A. N.; Hughes, E.; O'Muircheartaigh, J.; Duff, E.; Tuulari, J. J.; Deco, G.; Counsell, S. J.; Nosarti, C.; Arichi, T.; Edwards, D.; McAlonan, G.; Batalle, D.
10.1101/2022.11.16.516610 — neuroscience — Posted on 2022-11-17
1562 Assigning functionality to cysteines by base editing of cancer dependency genes
Li, H.; Remsberg, J.; Won, S. J.; Zhao, K.; Huang, T.; Lu, B.; Simon, G.; Liu, D.; Cravatt, B.
10.1101/2022.11.17.516964 — systems biology — Posted on 2022-11-17
1563 Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia
Gilioli, D.; Fusco, S.; Tavella, T.; Giannetti, K.; Conti, A.; Santoro, A.; Carsana, E.; Beretta, S.; Schonlein, M.; Gambacorta, V.; Aletti, F. M.; Carraba, M. G.; Bonini, C.; Ciceri, F.; Merelli, I.; Vago, L.; Schmitt, C. A.; Di Micco, R.
10.1101/2022.11.17.515658 — cancer biology — Posted on 2022-11-17
1564 Phosphatidylserine-exposing medium/large extracellular vesicles: potential cancer biomarkers
Perez, G. I.; Bernard, M. P.; Vocelle, D.; Zarea, A. A.; Schneider, D.; Bauzon, M.; Hermiston, T.; Kanada, M.
10.1101/2022.11.17.516966 — cancer biology — Posted on 2022-11-17
1565 Whole genome error-corrected sequencing for sensitive circulating tumor DNA cancer monitoring
Cheng, A. P.; Widman, A. J.; Arora, A.; Rusinek, I.; Hooper, W. F.; Murray, R.; Halmos, D.; Langanay, T.; Inghirami, G.; Germer, S.; Marton, M.; Manaa, D.; Helland, A.; Furatero, R.; McClintock, J.; Winterkorn, L.; Steinsnyder, Z.; Wang, Y.; Rajagopalan, S.; Alimohamed, A. I.; Malbari, M. S.; Saxena, A.; Callahan, M. K.; Frederick, D. T.; Spain, L.; Jaimovich, A.; Lipson, D.; Turajlic, S.; Zody, M. C.; Altorki, N. K.; Wolchok, J. D.; Postow, M. A.; Robine, N.; Boland, G.; Landau, D. A.
10.1101/2022.11.17.516904 — genomics — Posted on 2022-11-17
1566 Evolutionary insights from profiling LINE-1 activity at allelic resolution in a single human genome
Yang, L.; Metzger, G. A.; Padilla Del Valle, R.; Delgadillo Rubalcaba, D.; McLaughlin, R. N.
10.1101/2022.11.17.516944 — genetics — Posted on 2022-11-17
1567 Branched germline cysts and female-specific cyst fragmentation facilitate oocyte determination in mice
Ikami, K.; Shoffner, S.; Weh, M. G. T.; Schnell, S.; Ma, J.; Yoshida, S.; Miranda, E. D.; Ko, S.; Lei, L.
10.1101/2022.11.17.516957 — developmental biology — Posted on 2022-11-17
1568 IκBα controls dormancy induction in Hematopoietic stem cell development via retinoic acid
Thambyrajah, R.; Fadlullah, Z.; Proffitt, M.; Neo, W. H.; Guillen, Y.; Casado-Pelaez, M.; Herrero-Molinero, P.; Brujas, C.; Castelluccio, N.; Gonzalez, J.; Iglesias, A.; Marruecos, L.; Ruiz-Herguido, C.; Esteller, M.; Mereu, E.; Lacaud, G.; Espinosa, L.; Bigas, A.
10.1101/2022.11.17.516971 — cell biology — Posted on 2022-11-17
1570 Potently neutralizing human monoclonal antibodies against the zoonotic pararubulavirus Sosuga virus
Parrington, H. M.; Kose, N.; Armstrong, E.; Handal, L. S.; Diaz, S.; Reidy, J. X.; Dong, J.; Stewart-Jones, G. B. E.; Shrivastava-Ranjan, P.; Jain, S.; Albarino, C. G.; Carnahan, R. H.; Crowe, J. E.
10.1101/2022.11.17.516973 — immunology — Posted on 2022-11-17
1572 Rapid Single-Shot Synthesis of the 217 Amino Acid-Long N-Terminal Domain of Pyocin S2
Saebi, A.; Brown, J. S.; Marando, V. M.; Hartrampf, N.; Chumbler, N. M.; Hanna, S.; Poskus, M.; Loas, A.; Kiessling, L. L.; Hung, D. T.; Pentelute, B. L.
10.1101/2022.11.17.516969 — synthetic biology — Posted on 2022-11-17
1573 Toxicity impacts on human adipose MSCs acutely exposed to Aroclor and non-Aroclor mixtures of PCBs.
Behan-Bush, R. M.; Liszewski, J. N.; Schrodt, M. V.; Vats, B.; Li, X.; Lehmler, H.-J.; Klingelhutz, A. J.; Ankrum, J. A.
10.1101/2022.11.17.516943 — pharmacology and toxicology — Posted on 2022-11-17
1574 Determining the toxicity and potential for environmental transport of pyridine using the brown crab Cancer pagurus (L.)
Eastabrook, C. L.; Morales Maqueda, M.; Vagg, C.; Idomeh, J.; Nasif-Whiteshone, T.; Lawrence, P.; Bronowska, A.; Bothwell, J. H.; Sallach, B.; Redfern, J.; Caldwell, G. S.
10.1101/2022.11.17.516169 — pharmacology and toxicology — Posted on 2022-11-17
1575 DeepBryo: a web app for AI-assisted morphometric characterization of cheilostome bryozoans
Di Martino, E.; Berning, B.; Gordon, D. P.; Kuklinski, P.; Liow, L. H.; Ramsfjell, M. H.; Ribeiro, H. L.; Smith, A. M.; Taylor, P. D.; Voje, K. L.; Waeschenbach, A.; Porto, A.
10.1101/2022.11.17.516938 — bioinformatics — Posted on 2022-11-17
1576 Identification of genomic alterations with clinical impact in canine splenic hemangiosarcoma
Estabrooks, T.; Gurinovich, A.; Pietruska, J.; Lewis, B.; Harvey, G.; Post, G.; Lambert, L.; Rodrigues, L. C.; White, M. E.; Lopes, C.; London, C. A.; Megquier, K.
10.1101/2022.11.17.516327 — genomics — Posted on 2022-11-17
1578 Standardization of Data Analysis for RT-QuIC-based Detection of Chronic Wasting Disease
Rowden, G.; Picasso-Risso, C.; Li, M.; Schwabenlander, M. D.; Wolf, T. M.; Larsen, P. A.
10.1101/2022.11.17.516950 — molecular biology — Posted on 2022-11-17
1579 Improved Neutralization of Omicron BA.4/5, BA.4.6, BA.2.75.2, BQ.1.1, and XBB.1 with Bivalent BA.4/5 Vaccine
Zou, J.; Kurhade, C.; Patel, S.; Kitchin, N.; Tompkins, K.; Cutler, M.; Cooper, D.; Yang, Q.; Cai, H.; Muik, A.; Zhang, Y.; Lee, D.-Y.; Sahin, U.; Anderson, A. S.; Gruber, W. C.; Xie, X.; Swanson, K. A.; Shi, P.-Y.
10.1101/2022.11.17.516898 — microbiology — Posted on 2022-11-17
1580 Autotrophic biofilms sustained by deeply-sourced groundwater host diverse CPR bacteria implicated in sulfur and hydrogen metabolism
Alvarado, L. E. V.; Fakra, S. C.; Probst, A. J.; Giska, J. R.; Jaffe, A. L.; Oltrogge, L. M.; West-Roberts, J.; Rowland, J.; Manga, M.; Savage, D. F.; Greening, C.; Baker, B. J.; Banfield, J. F.
10.1101/2022.11.17.516901 — microbiology — Posted on 2022-11-17
1581 KDM5A/B promotes HIV-1 latency and KDM5 inhibitors promote HIV-1 lytic reactivation
Li, T.-W.; Zhou, D.; Wu, Z.; Fiches, G. N.; Wang, X.; Park, Y.; Jiang, W.; Ho, W.-Z.; Badley, A. D.; Santoso, N. G.; Qi, J.; Zhu, J.
10.1101/2022.11.17.516956 — microbiology — Posted on 2022-11-17
1584 Quantitative analyses of T cell motion in tissue reveals factors driving T cell search in tissues
Torres, D. J.; Mrass, P.; Byrum, J.; Gonzales, A.; Martinez, D.; Juarez, M. E.; Thompson, E.; Vezys, V.; Cannon, J. L.
10.1101/2022.11.17.516891 — immunology — Posted on 2022-11-17
1585 Inflammatory ER Stress Responses Dictate the Immunopathogenic Progression of Systemic Candidiasis
Awasthi, D.; Chopra, S.; Cho, B. A.; Emmanuelli, A.; Sandoval, T. A.; Hwang, S.-M.; Chae, C.-S.; Salvagno, C.; Tan, C.; Vasquez-Urbina, L.; Fernandez Rodriguez, J. J.; Santagostino, S. F.; Iwawaki, T. R.; Romero-Sandoval, E. A.; Sanchez Crespo, M.; Morales, D. K.; Iliev, I. D.; Hohl, T. M.; Cubillos-Ruiz, J. R.
10.1101/2022.11.17.513879 — immunology — Posted on 2022-11-17
1586 DNAJB6 Isoform Specific Knockdown: Therapeutic Potential for LGMDD1
Findlay, A. R.; Paing, M. M.; Daw, J. A.; Bengoechea, R.; Pittman, S. K.; Li, S.; Wang, F.; Miller, T. M.; True, H. L.; Weihl, C. C.
10.1101/2022.11.17.516920 — neuroscience — Posted on 2022-11-17
1587 Binding Site-enhanced Sequence Pretraining and Out-of-cluster Meta-learning Predict Genome-Wide Chemical-Protein Interactions for Dark Proteins
Cai, T.; Xie, L.; Zhang, S.; Chen, M.; He, D.; Badkul, A.; Liu, Y.; Namballa, H. K.; Dorogan, M.; Harding, W. W.; Mura, C.; Bourne, P. E.; Xie, L.
10.1101/2022.11.15.516682 — systems biology — Posted on 2022-11-17
1589 Structure and dynamics of human perilipin 3 membrane association
Choi, Y.-M.; Ajjaji, D.; Fleming, K. D.; Borbat, P. P.; Jenkins, M. L.; Moeller, B. E.; Freed, J. H.; Burke, J. E.; Thiam, A. R.; Airola, M. V.
10.1101/2022.11.17.516819 — biochemistry — Posted on 2022-11-17
1590 Wenzhou shrimp virus 8 (WzSV8) detection by unique inclusions in shrimp hepatopancreatic E-cellsand by RT-PCR
Srisala, J.; Thaiue, D.; Saguanrut, P.; Taengchaiyaphum, S.; Flegel, T. W.; Sritunyalucksana, K.
10.1101/2022.08.15.504032 — zoology — Posted on 2022-11-17
1592 Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
Rinaldi, C.; Waters, C. S.; Kumbier, K.; Rao, L.; Nichols, R. J.; Jacobson, M. P.; Wu, L. F.; Altschuler, S. J.
10.1101/2022.10.25.513743 — systems biology — Posted on 2022-11-17
1593 A secreted protease-like protein in Zymoseptoria tritici is responsible for avirulence on Stb9 resistance gene in wheat
AMEZROU, R.; AUDEON, C.; COMPAIN, J.; GELISSE, S.; DUCASSE, A.; SAINTENAC, C.; LAPALU, N.; ORFORD, S.; CROLL, D.; AMSELEM, J.; FILLINGER, S.; MARCEL, T. C.
10.1101/2022.10.31.514577 — plant biology — Posted on 2022-11-17
1595 Differential Histone-DNA Interactions Dictate Nucleosome Recognition of the Pioneer Transcription Factor Sox
Ozden, B.; Boopathi, R.; Barlas, A. B.; Lone, I. N.; Bednar, J.; Petosa, C.; Kale, S.; Hamiche, A.; Angelov, D.; Dimitrov, S.; Karaca, E.
10.1101/2021.12.07.471700 — biophysics — Posted on 2022-11-17
1598 Histone deacetylase 3 regulates microglial function through histone deacetylation
Meleady, L.; Towriss, M.; Kim, J.; Bacarac, V.; Rowland, M.; Ciernia, A. V.
10.1101/2022.09.08.507183 — neuroscience — Posted on 2022-11-17
1600 Sex differences in pain: Spinal cord injury in female and male mice elicits neuropathic pain symptoms
Lee, S. E.; Greenough, E. K.; Oancea, P.; Scheinfeld, A. R.; Douglas, A. M.; Gaudet, A. D.
10.1101/2022.10.18.512805 — neuroscience — Posted on 2022-11-17
1601 Eelbrain: A Python toolkit for time-continuous analysis with temporal response functions
Brodbeck, C.; Das, P.; Gillis, M.; Kulasingham, J. P.; Bhattasali, S.; Gaston, P.; Resnik, P.; Simon, J. Z.
10.1101/2021.08.01.454687 — neuroscience — Posted on 2022-11-17
1602 An Optrode Array for Spatiotemporally Precise Large-Scale Optogenetic Stimulation of Deep Cortical Layers in Non-human Primates
Clark, A. M.; Ingold, A.; Reiche, C. F.; Cundy, D.; Balsor, J. L.; Federer, F.; McAlinden, N.; Cheng, Y.; Rolston, J. D.; Rieth, L.; Dawson, M. D.; Mathieson, K.; Blair, S.; Angelucci, A.
10.1101/2022.02.09.479779 — neuroscience — Posted on 2022-11-17
1603 Functional and microstructural plasticity following social and interoceptive mental training.
Valk, S. L.; Kanske, P.; Park, B.-y.; Hong, S.-J.; Boeckler, A.; Trautwein, F.-M.; Bernhardt, B. C.; Singer, T.
10.1101/2020.11.11.377895 — neuroscience — Posted on 2022-11-17
1608 Weakly supervised identification of microscopic human breast cancer-related optical signatures from normal-appearing breast tissue
Shi, J.; Tu, H.; Park, J.; Marjanovic, M.; Higham, A. M.; Luckey, N. N.; Cradock, K. A.; Liu, Z. G.; Boppart, S. A.
10.1101/2022.05.24.493356 — bioinformatics — Posted on 2022-11-17
1609 Rapid evolutionary diversification of the flamenco locus in the D. simulans clade
Signor, S.; Vedanayagam, J.; Kim, B. Y.; Wierzbicki, F.; Kofler, R.; Lai, E. C.
10.1101/2022.09.29.510127 — evolutionary biology — Posted on 2022-11-17
1610 Transcriptional regulation and repressive condensates modulate a proliferative-invasive cellular switch in vivo
Medwig-Kinney, T. N.; Kinney, B. A.; Martinez, M. A. Q.; Yee, C.; Sirota, S. S.; Mullarkey, A. A.; Somineni, N.; Hippler, J.; Zhang, W.; Shen, K.; Hammell, C. M.; Pani, A. M.; Matus, D. Q.
10.1101/2022.09.30.510381 — developmental biology — Posted on 2022-11-17
1611 Adaptation to ex vivo culture drives human haematopoietic stem cell loss of repopulation capacity in a cell cycle independent manner
Johnson, C. S.; Sham, K.; Belluschi, S.; Wang, X.; Lau, W.; Kaufmann, K. B.; Krivdova, G.; Calderbank, E. F.; Mende, N.; McLeod, J.; Mantica, G.; Williams, M. J.; Grey-Wilson, C.; Drakopoulos, M.; Sinha, S.; Diamanti, E.; Basford, C.; Green, A. R.; Wilson, N. K.; Howe, S. J.; Dick, J. E.; Gottgens, B.; Francis, N.; Laurenti, E.
10.1101/2022.11.17.516906 — cell biology — Posted on 2022-11-17
1612 ESYT1 tethers the endoplasmic reticulum to mitochondria and is required for mitochondrial lipid and calcium homeostasis
Janer, A.; Morris, J. L.; Krols, M.; Antonicka, H.; Aaltonen, M. J.; Lin, Z.-Y.; Gingras, A.-C.; Prudent, J.; Shoubridge, E. A.
10.1101/2022.11.14.516495 — cell biology — Posted on 2022-11-17
1613 Spatial Localization Ability of Planarians Identified Through the Light Maze Paradigm
Qian, R.; Yan, Y.; Zhang, Y.; Chi, Y.; Chen, Y.; Hao, K.; Xu, Z.; Yang, G.; Shao, Z.; Wang, Y.; Li, X.; Lu, C.; Chen, K.; Pei, Y.; Zhang, W.; Wang, B.; Ying, Z.; Huang, K.
10.1101/2022.11.17.516918 — animal behavior and cognition — Posted on 2022-11-17
1615 Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies
Planas, D.; Bruel, T.; Staropoli, I.; Guivel-Benhassine, F.; Porrot, F.; Maes, P.; Grzelak, L.; Prot, M.; Mougari, S.; Planchais, C.; Puech, J.; Saliba, M.; Sahraoui, R.; Femy, F.; Morel, N.; Dufloo, J.; Sanjuan, R.; Mouquet, H.; Andre, E.; Hocqueloux, L.; Simon-Loriere, E.; Veyer, D.; Prazuck, T.; Pere, H.; Schwartz, O.
10.1101/2022.11.17.516888 — microbiology — Posted on 2022-11-17
1616 Free energy perturbation calculations of mutation effects on SARS-CoV-2 RBD::ACE2 binding affinity
Sergeeva, A. P.; Katsamba, P. S.; Sampson, J. M.; Bahna, F.; Mannepalli, S.; Morano, N. C.; Shapiro, L.; Friesner, R. A.; Honig, B.
10.1101/2022.08.01.502301 — biophysics — Posted on 2022-11-17
1619 The Cul5 E3 Ligase Complex Is a Key Negative Feedback Regulator of TCR/IL2 Signaling and Anti-Tumor Activity in CD8+ T Cells
Liao, X.; Li, W.; Li, A.; Rajendran, B. K.; Ren, J.; Zhou, H.; Calderwood, D.; Turk, B.; Tang, W.; Liu, Y.; Wu, D.
10.1101/2022.11.16.516824 — immunology — Posted on 2022-11-17
1622 A cell circuit approach to dissect fibroblast-macrophage interactions in the tumor microenvironment
Mayer, S.; Milo, T.; Isaacson, A.; Halperin, C.; Miyara, S.; Stein, Y.; Pevsner-Fischer, M.; Tzahor, E.; Alon, U.; Scherz-Shouval, R.
10.1101/2022.11.17.516850 — cancer biology — Posted on 2022-11-17
1623 DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer
Zhivagui, M.; Hoda, A.; Valenzuela, N.; Yeh, Y.-Y.; Dai, J.; He, Y.; Nandi, S.; Otlu, B.; Van Houten, B.; Alexandrov, L. B.
10.1101/2021.02.03.429605 — cancer biology — Posted on 2022-11-17
1624 Dynamic traction force measurements of migrating immune cells in 3D matrices
Boehringer, D.; Condor, M.; Bischof, L.; Czerwinski, T.; Bauer, A.; Voskens, C.; Budday, S.; Mark, C.; Fabry, B.; Gerum, R.
10.1101/2022.11.16.516758 — biophysics — Posted on 2022-11-17
1627 Cell response to extracellular matrix energy dissipation outweighs rigidity sensing
Huerta-Lopez, C.; Clemente-Manteca, A.; Velazquez-Carreras, D.; Espinosa, F. M.; Sanchez, J. G.; Saez, P.; Martinez-del-Pozo, A.; Garcia-Garcia, M.; Martin-Colomo, S.; Rodriguez-Blanco, A.; Esteban-Gonzalez, R.; Martin-Zamora, F. M.; Gutierrez-Rus, L.; Garcia, R.; Roca-Cusachs, P.; Elosegui-Artola, A.; del Pozo, M. A.; Herrero-Galan, E.; Plaza, G. R.; Alegre-Cebollada, J.
10.1101/2022.11.16.516826 — bioengineering — Posted on 2022-11-17
1628 Microlenses fabricated by two-photon laser polymerisation for intravital cell imaging with non-linear excitation microscopy
Marini, M.; Nardini, A.; Martinez Vazquez, R.; Conci, C.; Bouzin, M.; Collini, M.; Osellame, R.; Cerullo, G.; Kariman, B. S.; Farsari, M.; Kabouraki, E.; Raimondi, M. T.; Chirico, G.
10.1101/2022.11.17.516871 — bioengineering — Posted on 2022-11-17
1629 A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Thijssen, V.; Hurdiss, D. L.; Debski-Antoniak, O. J.; Spence, M. A.; Franck, C.; Norman, A.; Aggarwal, A.; Mokiem, N. J.; van Dongen, D. A. A.; Vermeir, S. W.; Liu, M.; Chatziandreou, M.; Donselaar, T.; Du, W.; Drulyte, I.; Bosch, B. J.; Snijder, J.; Turville, S. G.; Payne, R. J.; Jackson, C. J.; van Kuppeveld, F. J. M.; Jongkees, S. A. K.
10.1101/2022.11.11.516114 — biochemistry — Posted on 2022-11-17
1632 Histone exchange sensors reveal variant specific dynamics in mouse embryonic stem cells
Dunjic, M.; Jonas, F.; Yaakov, G.; More, R.; Mayshar, Y.; Rais, Y.; Barkai, N.; Stelzer, Y.
10.1101/2022.11.16.516734 — genomics — Posted on 2022-11-17
1636 Tree growth enhancement drives a persistent biomass gain in unmanaged temperate forests
Marques, L.; Weng, E.; Bugmann, H.; Forrester, D. I.; Rohner, B.; Hobi, M. L.; Trotsiuk, V.; Stocker, B. D.
10.1101/2022.11.16.516717 — ecology — Posted on 2022-11-17
1641 Three-dimensional molecular architecture of mouse organogenesis
Qu, F.; Li, W.; Xu, J.; Zhang, R.; Ke, J.; Ren, X.; Meng, X.; Qin, L.; Zhang, J.; Lu, F.; Zhang, Z.; Zhou, X.; Luo, X.; Wu, G.; Pei, D.; Chen, J.; Cui, G.; Suo, S.; Peng, G.
10.1101/2022.11.17.516228 — developmental biology — Posted on 2022-11-17
1642 A stable reference human transcriptome and proteome as a standard for reproducible omics experiments
Lu, S.; Lu, H.; Zheng, T.; Yuan, H.; Du, H.; Gao, Y.; Liu, Y.; Pan, X.; Zhang, W.; Fu, S.; Sun, Z.; Jin, J.; He, Q.-Y.; Chen, Y.; Zhang, G.
10.1101/2022.11.16.516732 — cell biology — Posted on 2022-11-17
1643 Initiation of fibronectin fibrillogenesis is an enzyme-dependent process
Melamed, S.; Zaffryar-Eilot, S.; Nadjar-Boger, E.; Aviram, R.; Zhao, H.; Yaseen-Badarne, W.; Kalev-Altman, R.; Sela-Donenfeld, D.; Lewinson, O.; Astrof, S.; Hasson, P.; Wolfenson, H.
10.1101/2022.11.16.516843 — cell biology — Posted on 2022-11-17
1646 BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B12 uptake in gut Bacteroides.
Abellon-Ruiz, J.; Jana, K.; Silale, A.; Frey, A. M.; Basle, A.; Trost, M.; Kleinekathofer, U.; van den Berg, B.
10.1101/2022.11.17.516869 — microbiology — Posted on 2022-11-17
1647 Genome-wide libraries for protozoan pathogens drug target screening using yeast surface display
Heslop, R.; Gao, M.; Brito Lira, A.; Sternlieb, T.; Loock, M.; Sanghi, S. R.; Cestari, I.
10.1101/2022.11.17.516844 — microbiology — Posted on 2022-11-17
1648 Evidence for a putative isoprene reductase in Acetobacterium wieringae
Kronen, M.; Vazquez-Campos, X.; Wilkins, M. R.; Lee, M.; Manefield, M. J.
10.1101/2022.11.16.516518 — microbiology — Posted on 2022-11-17
1649 Malaria drives unique regulatory responses across multiple immune cell subsets
Dooley, N. L.; Pava, Z.; Loughland, J. R.; Hamelink, J.; Berry, K.; Andrew, D.; Soon, M. S. F.; SheelaNair, A.; Piera, K. A.; William, T.; Barber, B.; Grigg, M. J.; Engwerda, C. R.; Lopez, J. A.; Anstey, N. M.; Boyle, M. J.
10.1101/2022.11.16.516822 — immunology — Posted on 2022-11-17
1650 A dynamic atlas of immunocyte migration from the gut
Galvan-Pena, S.; Zhu, Y.; Hanna, B. S.; Mathis, D.; Benoist, C.
10.1101/2022.11.16.516757 — immunology — Posted on 2022-11-17
1651 Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD
Li, J.; Jaiswal, M. K.; Chien, J.-F.; Kozlenkov, A.; Zhou, P.; Gardashli, M.; Pregent, L. J.; Engelberg-Cook, E.; Dickson, D. W.; Belzil, V. V.; Mukamel, E. A.; Dracheva, S.
10.1101/2022.11.17.516859 — neuroscience — Posted on 2022-11-17
1654 Brain-age prediction: a systematic comparison of machine learning workflows
More, S.; Antonopoulos, G.; Hoffstaedter, F.; Caspers, J.; Eickhoff, S. B.; Patil, K. R.
10.1101/2022.11.16.515405 — neuroscience — Posted on 2022-11-17
1655 A tonically active neuron continuously drives mutually exclusive motor states at different timescales
Meng, J.; Ahamed, T.; Yu, B.; Hung, W.; El Mouridi, S.; Zhang, Z.; Wang, Z.; Wen, Q.; Boulin, T.; Gao, S.; Zhen, M.
10.1101/2022.04.06.487231 — neuroscience — Posted on 2022-11-17
1658 Real-time library search increases cross-link identification depth across all levels of sample complexity
Ruwolt, M.; He, Y.; Lima, D. B.; Barshop, W.; Broichhagen, J.; Huguet, R.; Viner, R.; Liu, F.
10.1101/2022.11.16.516769 — systems biology — Posted on 2022-11-17
1664 Synergy of HLA class I and II shapes the timing of antitumor immune response
Papp, B. T.; Fulop, A. T.; Balogh, G. M.; Koncz, B.; Spekhardt, D.; Manczinger, M.
10.1101/2022.11.16.516740 — cancer biology — Posted on 2022-11-17
1665 Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis
Pontius, W. D.; Hong, E. S.; Faber, Z. J.; Gray, J.; Peacock, C.; Bayles, I.; Lovrenert, K.; Bartels, C. F.; Scacheri, P. C.
10.1101/2022.11.15.516627 — cancer biology — Posted on 2022-11-17
1666 A combination of Metformin and Epigallocatechin Gallate Potentiates Glioma Chemotherapy in vivo
Kuduvalli, S. S.; S, D. P.; Vaithy, A.; Purushothaman, M.; Muralidharan, A. R.; Kumar B, A.; Mezger, M.; Antony, J. S.; Subramani, M.; Dubashi, B.; Biswas, I.; K P, G.; T. S, A.
10.1101/2022.11.16.516766 — cancer biology — Posted on 2022-11-17
1673 Comparative Mucomic Analysis of Three Functionally Distinct Cornu aspersum Secretions
Cerullo, A. R.; McDermott, M.; Pepi, L. E.; Liu, Z.-L.; Barry, D.; Zhang, S.; Chen, X.; Azadi, P.; Holford, M.; Braunschweig, A. B.
10.1101/2022.11.16.516827 — biochemistry — Posted on 2022-11-17
1674 Multi-'Omic Integration via Similarity Network Fusion to Detect Molecular Subtypes of Aging
Yang, M.; Matan-Lithwick, S.; Wang, Y.; De Jager, P.; Bennett, D. A.; Felsky, D.
10.1101/2022.11.16.516806 — genomics — Posted on 2022-11-17
1676 Rapid and Signal Crowdedness-Robust In-Situ Sequencing through Hybrid Block Coding
Chang, T.; Han, W.; Jiang, M.; Li, J.; Shen, J.; Chen, Z.; Fei, P.; Ren, X.; Pang, Y.; Wang, G.; Wang, J.; Huang, Y.
10.1101/2022.11.16.516714 — genomics — Posted on 2022-11-17
1682 Epigenetic variation in the Lombardy poplar along climatic gradients is independent of genetic structure and persists across clonal reproduction
Diez Rodriguez, B.; Galanti, D.; Nunn, A.; Pena-Ponton, C.; Perez-Bello, P.; Sammarco, I.; Jandrasits, K.; Becker, C.; De Paoli, E.; Verhoeven, K. J. F.; Opgenoorth, L.; Heer, K.
10.1101/2022.11.17.516862 — ecology — Posted on 2022-11-17
1684 Amino acid intake strategies define pluripotent cell states
Todorova, P. K.; Jackson, B. T.; Garg, V.; Paras, K. I.; Chen, Y.; Baksh, S. C.; Yan, J.; Hadjantonakis, A.-K.; Finley, L.
10.1101/2022.11.16.516803 — developmental biology — Posted on 2022-11-17
1685 ETV2 upregulation marks the specification of early cardiomyocytes and endothelial cells during co-differentiation
Cao, X.; Mircea, M.; Yakala, G. K.; van den Hil, F. E.; Brescia, M.; Mei, H.; Mummery, C. L.; Semrau, S.; Orlova, V. V.
10.1101/2022.11.15.516686 — developmental biology — Posted on 2022-11-17
1687 Cas9-mediated tagging of endogenous loci using HITAG
Kim, J.; Kratz, A.; Sheng, J.; Zhang, L.; Singh, B. K.; Chavez, A.
10.1101/2022.11.16.516691 — cell biology — Posted on 2022-11-17
1688 Novel therapeutic strategies for injured endometrium: Autologous intrauterine transplantation of menstrual blood-derived cells from infertile patients
Hosoya, S.; Yokomizo, R.; Kishigami, H.; Fujiki, Y.; Kaneko, E.; Amita, M.; Saito, T.; Kishi, H.; Sago, H.; Okamoto, A.; UMEZAWA, A.
10.1101/2022.11.17.516854 — cell biology — Posted on 2022-11-17
1689 Wsc1 acts as a piezosensor in Saccharomyces cerevisiae, enhancing glycerol efflux via aquaglyceroporin Fps1 in response to high hydrostatic pressure
Mochizuki, T.; Tanigawa, T.; Shindo, S.; Suematsu, M.; Oguchi, Y.; Mioka, T.; Kato, Y.; Fujiyama, M.; Hatano, E.; Yamaguchi, M.; Chibana, H.; Abe, F.
10.1101/2022.11.15.516693 — cell biology — Posted on 2022-11-17
1690 A Legionella pneumophila effector impedes host gene silencing to promote virulence
Toinon, J.; Rolando, M.; Charvin, M.; Filopon, D.; Schiavolin, L.; Sy, K. A.; Vu, H.-C.; Gallois-Montbrun, S.; Alam, A.; Rusniok, C.; Lombard, B.; Loew, D.; Buchrieser, C.; Navarro, L.
10.1101/2022.11.16.516792 — molecular biology — Posted on 2022-11-17
1692 Structured surveys of Australian native possum excreta predict Buruli ulcer occurrence in humans
Vandelannoote, K.; Buultjens, A. H.; Porter, J. L.; Velink, A.; Wallace, J. R.; Blasdell, K. R.; Dunn, M.; Boyd, V.; Fyfe, J. A. M.; Tay, E. L.; Johnson, P. D. R.; Windecker, S.; Golding, N.; Stinear, T. P.
10.1101/2022.11.16.516821 — microbiology — Posted on 2022-11-17
1693 An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis
Reuter, J.; Otten, C.; Jacquier, N.; Lee, J.; Mengin-Lecreulx, D.; Loeckener, I.; Mayer, R.; Corona, F.; Dannenberg, J.; Aeby, S.; Buehl, H.; Greub, G.; Vollmer, W.; Schneider, T.; Henrichfreise, B.
10.1101/2022.11.17.516864 — microbiology — Posted on 2022-11-17
1696 Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung.
Kersten, K.; You, R.; Liang, S.; Tharp, K.; Pollack, J.; Weaver, V. M.; Krummel, M. F.; Headley, M. B.
10.1101/2022.11.15.516217 — immunology — Posted on 2022-11-17
1699 Consciousness is indexed by analogous cortical reorganization during sleep and anesthesia
Krause, B. M.; Campbell, D. I.; Kovach, C. K.; Mueller, R. N.; Kawasaki, H.; Nourski, K. V.; Banks, M. I.
10.1101/2022.11.15.516653 — neuroscience — Posted on 2022-11-17
1700 Histone H2A monoubiquitination in the thalamus regulates cocaine effects and addiction risk
Cheron, J.; Beccari, L.; Hague, P.; Icick, R.; Defrance, M.; Carusone, T.; Despontin, C.; Bhogaraju, S.; Vorspan, F.; Bonnefont, J.; de Kerchove d'Exaerde, A.
10.1101/2022.11.16.516716 — neuroscience — Posted on 2022-11-17
1701 Targeting Staufen 1 with antisense oligonucleotides for treating ALS and SCA2
Scoles, D. R.; Paul, S.; Dansithong, W.; Figueroa, K. P.; Gandelman, M.; Royzen, F.; Anderson, C. J.; Pulst, S. M.
10.1101/2022.11.16.516816 — neuroscience — Posted on 2022-11-17
1704 Cell type-specific assessment of cholesterol distribution in models of neurodevelopmental disorders
Czernecki, C.; Dixit, S.; Riezman, I.; Innocenti, S.; Pfrieger, F.; Riezman, H.; Scheiffele, P.
10.1101/2022.11.16.516849 — neuroscience — Posted on 2022-11-17
1705 Oscillatory brain networks in continuous speaking and listening
Abbasi, O.; Steingraeber, N.; Chalas, N.; Kluger, D. S.; Gross, J.
10.1101/2022.11.17.516860 — neuroscience — Posted on 2022-11-17
1706 Identifying genes and pathways linking astrocyte regional specificity to Alzheimer's disease susceptibility
Zhang, R.; Knudsen, M.; Vasques, P. D. C.; Tadych, A.; Rodriguez-Rodriguez, P.; Greengard, P.; Roussarie, J.-P.; Milosevic, A.; Troyanskaya, O. G.
10.1101/2022.11.16.515390 — systems biology — Posted on 2022-11-17
1707 Emergence of division of labor in tissues through cell interactions and spatial cues
Adler, M.; Moriel, N.; Goeva, A.; Avraham-Davidi, I.; Mages, S.; Adams, T. S.; Kaminski, N.; Macosko, E. Z.; Regev, A.; Medzhitov, R.; Nitzan, M.
10.1101/2022.11.16.516540 — systems biology — Posted on 2022-11-17
1708 Defining the Parameters to Improve Plant Regeneration with Developmental Regulators
Nasti, R. A.; Cody, J. P.; Zinselmeier, M. H.; Badey, N. B.; Sridhar, A.; Sharma, A.; Maher, M. F.; Blackman, B. K. A.; Voytas, D.
10.1101/2022.11.15.516675 — plant biology — Posted on 2022-11-17
1710 A study on packed cell volume for deducing hemoglobin: Cholistani camels in perspective
Farooq, U.; Idris, M.; Lashari, M. H.; Ahmad, S.; Sajjad, N.; Rehman, Z. U.; Rashid, H.; Mahmood, A.; Hameed, S.
10.1101/2022.11.15.516630 — physiology — Posted on 2022-11-17
1713 SLC25A51 impacts drug sensitivity in AML cells by sustaining mitochondrial oxidative flux
Lu, M.-J.; Busquets, J.; Impedovo, V.; Chang, Y.-T.; Matsui, W.; Tiziani, S.; Cambronne, X. A.
10.1101/2022.11.15.516643 — cancer biology — Posted on 2022-11-17
1714 Germline determinants of the prostate tumor genome
Houlahan, K. E.; Yuan, J.; Schwarz, T.; Livingstone, J.; Fox, N. S.; Jaratlerdsiri, W.; van Riet, J.; Taraszka, K.; Kurganovs, N.; Zhu, H.; Sietsma Penington, J.; Jung, C.-H.; Yamaguchi, T. N.; Jiang, J.; Heisler, L. E.; Jovelin, R.; Ramanand, S. G.; Bell, C.; O'Connor, E.; Mutambirwa, S. B. A.; Seo, J.-H.; Costello, A. J.; Pomerantz, M. M.; Pope, B. J.; Zaitlen, N.; Kishan, A. U.; Corcoran, N. M.; Bristow, R. G.; Waszak, S. M.; Bornman, R. M. S.; Gusev, A.; Lokema, M. P.; Weischenfeldt, J.; Hung, R.; He, H. H.; Hayes, V.; Pasaniuc, B.; Freedman, M.; Hovens, C. M.; Mani, R. S.; Boutros, P. C.
10.1101/2022.11.16.516773 — cancer biology — Posted on 2022-11-17
1715 A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer
Ware, K. E.; Thomas, B. C.; Olawuni, P.; Sheth, M. U.; Hawkey, N.; M, Y.; Miller, B. C.; Vietor, K.; Jolly, M. K.; Kim, S. Y.; Armstrong, A. J.; Somarelli, J. A.
10.1101/2022.11.15.516649 — cancer biology — Posted on 2022-11-17
1716 Analysis of cancer genomic amplifications identifies druggable collateral dependencies within the amplicon
Pons, G.; Gallo-Oller, G.; Navarro, N.; Zarzosa, P.; Sansa-Girona, J.; Garcia-Gilabert, L.; Magdaleno, A.; Segura, M. F.; Sanchez de Toledo, J.; Gallego, S.; Moreno, L.; Roma, J.
10.1101/2022.11.16.516737 — cancer biology — Posted on 2022-11-17
1721 ChromFormer: A transformer-based model for 3Dgenome structure prediction
Valeyre, H.; Pati, P.; Gossi, F.; Ram Somnath, V.; Martinelli, A. L.; Rapsomaniki, M. A.
10.1101/2022.11.15.516571 — bioinformatics — Posted on 2022-11-17
1722 Conformational epistasis impairs AlphaFold structural predictions
Sawicki, L. R.; Benitez, G. I.; Carletti, M. S.; Palopoli, N.; Fornasari, M. S.; Parisi, G. D.
10.1101/2022.11.15.516638 — bioinformatics — Posted on 2022-11-17
1727 Inferring a cell's capabilities from omics data with ImmCellFie
Masson, H. O.; Borland, D.; Reilly, J.; Telleria, A.; Shrivastava, S.; Watson, M.; Bustillo, L.; Li, Z.; Capps, L.; Kellman, B. P.; King, Z. A.; Richelle, A.; Lewis, N. E.; Robasky, K.
10.1101/2022.11.16.516672 — bioinformatics — Posted on 2022-11-17
1728 The effect of background noise and its removal on the analysis of single-cell expression data
Janssen, P.; Kliesmete, Z.; Vieth, B.; Adiconis, X.; Simmons, S.; Marshall, J.; McCabe, C.; Heyn, H.; Levin, J. Z.; Enard, W.; Hellmann, I.
10.1101/2022.11.16.516780 — bioinformatics — Posted on 2022-11-17
1729 Snapper: a high-sensitive algorithm to detect methylation motifs based on Oxford Nanopore reads
Konanov, D. N.; Babenko, V. N.; Belova, A. M.; Madan, A. G.; Boldyreva, D. I.; Glushchenko, O. E.; Butenko, I. O.; Fedorov, D. E.; Manolov, A. I.; Lazarev, V. N.; Govorun, V. M.; Ilina, E. N.
10.1101/2022.11.15.516621 — bioinformatics — Posted on 2022-11-17
1731 Quality control for the target decoy approach for peptide identification
Debrie, E.; Malfait, M.; Gabriels, R.; Declerq, A.; Sticker, A.; Martens, L.; Clement, L.
10.1101/2022.11.17.516857 — bioinformatics — Posted on 2022-11-17
1734 Graphene-based thin film microelectrode technology for in vivo high resolution neural recording and stimulation
Viana, D.; Walston, S. T.; Illa, X.; del Valle, J.; Hayward, A.; Dodd, A.; Loret, T.; Prats-Alfonso, E.; de la Oliva, N.; Palma, M.; del Corro, E.; Rodriguez-Meana, B.; Bernicola, M. d. P.; Rodriguez-Lucas, E.; Gener, T. A.; de la Cruz, J. M.; Torres-Miranda, M.; Duvan, F. T.; Ria, N.; Sperling, J.; Marti-Sanchez, S.; Chiara Spadaro, M.; Hebert, C.; Masvidal-Codina, E.; Savage, S.; Arbiol, J.; Guimera-Brunet, A.; Puig, M. V.; Navarro, X.; Yvert, B.; Kostarelos, K.; Garrido, J. A.
10.1101/2022.11.16.515761 — bioengineering — Posted on 2022-11-17
1735 Trabecular bone remodeling in the ageing mouse: a micro-multiphysics agent-based in silico model using cell-type-specific mechanomic profiles
Boaretti, D.; Marques, F. C.; Ledoux, C.; Singh, A.; Kendall, J. J.; Wehrle, E.; Kuhn, G. A.; Bansod, Y. D.; Schulte, F.; Müller, R.
10.1101/2022.11.16.516723 — bioengineering — Posted on 2022-11-17
1736 Coupling of perinuclear actin cap and nuclear mechanics regulates flow-induced YAP spatiotemporal nucleocytoplasmic transport
Ma, T.; Liu, X.; Su, H.; Li, S.; Gao, C.; Liang, Z.; Zhang, D.; Zhang, X.; Li, K.; Hu, K.; Wang, L.; Wang, M.; Wu, F.; Yue, S.; Hong, W.; Chen, X.; Deng, X.; Wang, P.; Fan, Y.
10.1101/2022.11.15.516697 — bioengineering — Posted on 2022-11-17
1738 Haplotype-resolved de novo genome assemblies of four coniferous tree species
Shirasawa, K.; Mishima, K.; Hirakawa, H.; Hirao, T.; Tsubomura, M.; Nagano, S.; Iki, T.; Isobe, S.; Takahashi, M.
10.1101/2022.11.16.516598 — genomics — Posted on 2022-11-17
1739 Characterizing the landscape of gene expression variance in humans
Wolf, S.; Melo, D.; Garske, K. M.; Pallares, L. F.; Ayroles, J. F.
10.1101/2022.11.15.516646 — genomics — Posted on 2022-11-17
1745 Traction force reconstruction assessment on real three-dimensional matrices and cellular morphologies
Apolinar-Fernandez, A.; Barrasa-Fano, J.; Condor, M.; Van Oosterwyck, H.; Sanz-Herrera, J. A.
10.1101/2022.11.16.516745 — cell biology — Posted on 2022-11-17
1750 68Ga-Bisphosphonates for the Imaging of Extraosseous Calcification by Positron Emission Tomography
Keeling, G.; Baark, F.; Katsamenis, O. L.; Xue, J.; Blower, P. J.; Bertazzo, S.; T. M. de Rosales, R.
10.1101/2022.11.15.516425 — pharmacology and toxicology — Posted on 2022-11-17
1756 Decoding trans-saccadic prediction error
Barne, L. C.; Giordano, J.; Collins, T.; Desantis, A.
10.1101/2022.03.21.485172 — neuroscience — Posted on 2022-11-17
1757 Targeting aggressive B-cell lymphomas through pharmacological activation of the mitochondrial protease OMA1
Schwarzer, A.; Oliveira, M.; Kleppa, M.-J.; Slattery, S. D.; Anantha, A.; Cooper, A.; Hannink, M.; Schambach, A.; Dorrie, A.; Kotlyarov, A.; Gaestel, M.; Hembrough, T.; Levine, J.; Luther, M.; Stocum, M.; Stiles, L.; Weinstock, D.; Liesa, M.; Kostura, M. J.
10.1101/2022.06.12.495213 — cancer biology — Posted on 2022-11-17
1759 Incorporating Pre-training Paradigm for Antibody Sequence-Structure Co-design
Gao, K.; Wu, L.; Zhu, J.; Peng, T.; Xia, Y.; He, L.; Xie, S.; Qin, T.; Liu, H.; He, K.; Liu, T.-Y.
10.1101/2022.11.14.516404 — molecular biology — Posted on 2022-11-17
1761 Myonuclear alterations associated with exercise are independent of age in humans
Battey, E.; Ross, J. A.; Hoang, A.; Wilson, D. G. S.; Han, Y.; Levy, Y.; Pollock, R. D.; Kalakoutis, M.; Pugh, J. N.; Close, G. L.; Ellison-Hughes, G. M.; Lazarus, N.; Harridge, S. D. R.; Iskratsch, T.; Ochala, J.; Stroud, M.
10.1101/2022.09.20.506578 — cell biology — Posted on 2022-11-17
1762 Non-invasive real-time genomic monitoring of the critically endangered kakapo
Urban, L.; Miller, A. K.; Eason, D.; Vercoe, D.; Shaffer, M.; Wilkinson, S. P.; Jeunen, G.-J.; Gemmell, N. J.; Digby, A.
10.1101/2022.11.14.516431 — genomics — Posted on 2022-11-17
1763 Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations
Huelsz-Prince, G.; Kok, R. N. U.; Goos, Y. J.; Bruens, L.; Zheng, X.; Ellenbroek, S. I. J.; van Rheenen, J.; Tans, S. J.; van Zon, J. S.
10.1101/2022.03.17.484731 — cell biology — Posted on 2022-11-17
1765 De-differentiation and Proliferation of Artery Endothelial Cells Drive Coronary Collateral Development
Arolkar, G.; K, S.; Wang, H.; Gonzalez, K. M.; Kumar, S.; Bishnoi, B.; Rios Coronado, P. E.; Woo, J. Y.; Red-Horse, K.; Das, S.
10.1101/2022.07.27.501689 — developmental biology — Posted on 2022-11-17
1766 Improved Protocol for Single Nucleus RNA-sequencing of Frozen Human Bladder Tumor Biopsies
Schmokel, S. S.; Nordentoft, I. K.; Lindskrog, S. V.; Lamy, P.; Knudsen, M.; Jensen, J. B.; Dyrskjot, L.
10.1101/2022.10.14.512220 — cancer biology — Posted on 2022-11-17
1767 Deciphering anti-infectious compounds from Peruvian medicinal Cordoncillos extract library through multiplexed assays and chemical profiling
Vasquez-Ocmin, P. G.; Cojean, S.; Roumy, V.; Marti, G.; Pomel, S.; Gadea, A.; Leblanc, K.; Dennemont, I.; Ruiz-Vasquez, L.; Cotrina, H. R.; Mesia, W. R.; Bertani, S.; Mesia, L. R.; Maciuk, A.
10.1101/2022.11.15.516654 — biochemistry — Posted on 2022-11-17
1769 A mechanism for the elimination of IgE plasma cells
Wade-Vallance, A. K.; Yang, Z.; Libang, J. B.; Robinson, M. J.; Tarlinton, D. M.; Allen, C. D. C.
10.1101/2022.05.11.491510 — immunology — Posted on 2022-11-17
1770 TCGADEPMAP -- Mapping Translational Dependencies and Synthetic Lethalities within The Cancer Genome Atlas
Shi, X.; Gekas, C.; Verduzco, D.; Petiwala, S.; Jeffries, C.; Lu, C.; Murphy, E.; Anton, T.; Vo, A.; Xiao, Z.; Narayanan, P.; Barnes, M.; Roy, S.; Ramathal, C.; Flister, M. J.; Dezso, Z.
10.1101/2022.03.24.485544 — cancer biology — Posted on 2022-11-16
1773 Cell type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening
Tan, J.; Shenker-Tauris, N.; Rodriguez-Hernaez, J.; Wang, E.; Sakellaropoulos, T.; Boccalatte, F.; Thandapani, P.; Skok, J.; Aifantis, I.; Fenyo, D.; Xia, B.; Tsirigos, A.
10.1101/2022.03.05.483136 — genomics — Posted on 2022-11-16
1776 Blebs Promote Cell Survival by Assembling Oncogenic Signaling Hubs
Weems, A. D.; Welf, E. S.; Driscoll, M. K.; Zhou, F.; Mazloom-Farsibaf, H.; Chang, B.-J.; Murali, V. S.; Gihana, G. M.; Weiss, B. G.; Chi, J.; Rajendran, D.; Dean, K. M.; Fiolka, R. P.; Danuser, G.
10.1101/2021.04.23.441200 — cell biology — Posted on 2022-11-16
1777 H4K16ac activates transcription of transposable elements and contribute to their cis regulatory function
Pal, D.; Patel, M.; Boulet, F.; Sundarraj, J.; Grant, O. A.; Branco, M. R.; Basu, S.; Santos, S.; Zabet, N. R.; Scaffidi, P.; Pradeepa, M. M.
10.1101/2022.04.29.488986 — molecular biology — Posted on 2022-11-16
1780 Neuroimaging alterations and relapse in early-stage psychosis
Mihaljevic, M.; Nagpal, A.; Etyemez, S.; Narita, Z.; Ross, A.; Schaub, R.; Cascella, N.; Coughlin, J. M.; Nestadt, G.; Nucifora, F. C.; Sedlak, T. W.; Ishizuka, K.; Calhoun, V.; Faria, A.; Yang, K.; Sawa, A.
10.1101/2021.12.10.472143 — neuroscience — Posted on 2022-11-16
1781 Using temperature to analyse the neural basis of a time-based decision
Monteiro, T.; Rodrigues, F. S.; Pexirra, M.; Cruz, B. F. P.; Goncalves, A. I.; Rueda-Orozco, P. E.; Paton, J. J.
10.1101/2020.08.24.251827 — neuroscience — Posted on 2022-11-16
1785 Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks
Wollman, A. J.; Syeda, A.; Howard, J.; Leech, A.; Guy, C.; McGlynn, P.; Hawkins, M.; Leake, M. C.
10.1101/2021.02.22.432310 — biophysics — Posted on 2022-11-16
1786 Context-Aware Transcript Quantification from Long Read RNA-Seq data with Bambu
Chen, Y.; Sim, A. D.; Wan, Y. K.; Yeo, K.; Lee, J. J. X.; Ling, M. H.; Love, M. I.; Göke, J.
10.1101/2022.11.14.516358 — bioinformatics — Posted on 2022-11-16
1791 Identification of Aryl Hydrocarbon Receptor as a Barrier to HIV-1 Infection and Outgrowth in CD4+ T-Cells
Chatterjee, D.; Zhang, Y.; Wiche Salinas, T. R.; Ngassaki-Yoka, C.-D.; Chen, H.; Smail, Y.; Goulet, J.-P.; Bell, B.; Routy, J.-P.; Ancuta, P.
10.1101/2022.10.17.512596 — immunology — Posted on 2022-11-16
1793 Necroptosis inhibition counteracts neurodegeneration, memory decline and key hallmarks of aging, promoting brain rejuvenation.
Arrazola, M. S.; Lira, M.; Quiroz, G.; Veliz-Valverde, F.; Iqbal, S.; Eaton, S. L.; Kline, R. A.; Lamont, D. J.; Huerta, H.; Ureta, G.; Bernales, S.; Cardenas, J. C.; Cerpa, W.; Wishart, T. M.; Court, F. A.
10.1101/2021.11.10.468052 — neuroscience — Posted on 2022-11-16
1797 Cooperative action of separate interaction domains promotes high-affinity DNA binding of Arabidopsis thaliana ARF transcription factors
Fontana, M.; Roosjen, M.; Crespo Garcia, I.; van den Berg, W.; Malfois, M.; Boer, R.; Weijers, D.; Hohlbein, J.
10.1101/2022.11.16.516730 — biochemistry — Posted on 2022-11-16
1799 Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions
Cornish, A.; Gruber, A.; Kinnersley, B.; Chubb, D.; Frangou, A.; Caravagna, G.; Noyvert, B.; Lakatos, E.; Wood, H.; Arnedo-Pac, C.; Culliford, R.; Househam, J.; Cross, W.; Sud, A.; Law, P.; Ni Leathlobhair, M.; Hawari, A.; Thorn, S.; Sherwood, K.; Gul, G.; Fernandez-Tajes, J.; Zapata, L.; Alexandrov, L.; Murugaesu, N.; Sosinsky, A.; Mitchell, J.; Lopez-Bigas, N.; Quirke, P.; Church, D.; Tomlinson, I.; Sottoriva, A.; Graham, T.; Wedge, D.; Houlston, R.
10.1101/2022.11.16.515599 — genomics — Posted on 2022-11-16
1800 Endo-parasitoid lifestyle promotes endogenization and domestication of dsDNA viruses
GUINET, B.; Lepetit, D.; Charlat, S.; Buhl, P. N.; Notton, D. G.; Cruaud, A.; Rasplus, J.-Y.; Stigenberg, J.; de Vienne, D. M.; Boussau, B.; Varaldi, J.
10.1101/2022.11.16.515002 — genomics — Posted on 2022-11-16
1803 SLC3A2 N-glycosylation and alternate evolutionary trajectories for amino acid metabolism
Zhang, C.; Shafaq-Zadah, M.; Pawling, J.; Hesketh, G. G.; Ng, D.; Dransart, E.; Pacholczyk, K.; Longo, J.; Gingras, A.-C.; Penn, L. Z.; Johannes, L.; Dennis, J. W.
10.1101/2022.11.15.516651 — cell biology — Posted on 2022-11-16
1804 The critical role of BTRC in hepatic steatosis as an ATGL E3 ligase
Qi, W.; Fang, Z.; Luo, C.; Hong, H.; Long, Y.; Dai, Z.; Liu, J.; Zeng, Y.; Zhou, T.; Xia, Y.; Yang, X.; Gao, G.
10.1101/2022.11.15.516629 — cell biology — Posted on 2022-11-16
1807 Pioneer factor Pax7 initiates two-step cell-cycle dependent chromatin opening
Gouhier, A.; Dumoulin-Gagnon, J.; Lapointe-Roberge, V.; Balsalobre, A.; DROUIN, J.
10.1101/2022.11.16.516735 — molecular biology — Posted on 2022-11-16
1810 Amplicon sequencing reveals complex infection in infants congenitally infected with Trypanosoma cruzi and informs the dynamics of parasite transmission
Hakim, J. M.; Waltmann, A.; Tinajeros, F.; Kharabora, O.; Malaga Machaca, E.; Calderon, M.; Menduina, M. d. C.; Wang, J.; Rueda, D.; Zimic, M.; Verastegui, M.; Juliano, J. J.; Gilman, R. H.; Mugnier, M. R.; Bowman, N. M.; Chagas working group,
10.1101/2022.11.16.516746 — microbiology — Posted on 2022-11-16
1811 Mycobacteria form viable cell wall-deficient cells that are undetectable by conventional diagnostics
Dannenberg, N.; Carrion Bravo, V.; Weijers, T.; Spaink, H.; Ottenhoff, T.; Briegel, A.; Claessen, D.
10.1101/2022.11.16.516772 — microbiology — Posted on 2022-11-16
1812 Contemporary human H3N2 influenza A viruses require a low threshold of suitable glycan receptors for efficient infection
Spruit, C. M.; Sweet, I. R.; Bestebroer, T.; Lexmond, P.; Qiu, B.; Damen, M. J.; Fouchier, R. A.; Snijder, J.; Herfst, S.; Boons, G.-J.; de Vries, R. P.
10.1101/2022.11.16.516725 — microbiology — Posted on 2022-11-16
1813 Endothelial Caveolin-1 and CXCL10 promote transcellular migration of autoreactive T cells across the blood-brain barrier
Trevino, T. N.; Almousawi, A. A.; Ochoa-Raya, A.; Zemanski, K.; Oliveira, S. D.; Marottoli, F. M.; Tai, L. M.; Minshall, R. D.; Lutz, S. E.
10.1101/2022.11.15.516689 — immunology — Posted on 2022-11-16
1815 Deep-learning based bioactive therapeutic peptides generation and screening
Zhang, H.; Saravanan, K. M.; Wei, Y.; Jiao, Y.; Yang, Y.; Pan, Y.; Wu, X.; Zhang, J. Z. H.
10.1101/2022.11.14.516530 — bioinformatics — Posted on 2022-11-16
1816 CRISPRi-Driven Osteogenesis in Adipose-Derived Stem Cells for Bone Healing and Tissue Engineering
Weston, J. D.; Austin, B.; Levis, H.; Zitnay, J.; Weiss, J. A.; Lawrence, B.; Bowles, R. D.
10.1101/2022.11.15.513563 — bioengineering — Posted on 2022-11-16
1817 Cross-linking mass spectrometry discovers, evaluates, and validates the experimental and predicted structural proteome
Bartolec, T. K.; Vazquez-Campos, X.; Norman, A.; Luong, C.; Payne, R. J.; Wilkins, M. R.; Mackay, J. P.; Low, J. K. K.
10.1101/2022.11.16.516813 — biochemistry — Posted on 2022-11-16
1818 Deciphering anti-infectious compounds from Peruvian medicinal Condocillos extract library through multiplexed assays and chemical profiling
Vasquez-Ocmin, P. G.; Cojean, S.; Roumy, V.; Marti, G.; Pomel, S.; Gadea, A.; Leblanc, K.; Dennemont, I.; Ruiz-Vasquez, L.; Cotrina, H. R.; Mesia, W. R.; Bertani, S.; Mesia, L. R.; Maciuk, A.
10.1101/2022.11.15.516654 — biochemistry — Posted on 2022-11-16
1821 Molecular epidemiology of Infectious Spleen and Kidney Necrosis Virus (ISKNV) in Ghanaian cultured tilapia
Ayiku, A. N. A.; Adelani, A. A.; Appenteng, P.; Nkansah, M.; Ngoi, J. M.; Morang'a, C. M.; Paley, R.; Cudjoe, K. S.; Verner-Jeffrey, D.; Quashie, P. K.; Duodu, S.
10.1101/2022.11.15.516701 — molecular biology — Posted on 2022-11-16
1824 LXR-inducible host E3 ligase IDOL targets a human cytomegalovirus reactivation determinant to promote latency
Mlera, L.; Zeltzer, S.; Collins-McMillen, D. K.; Buehler, J.; Moy, M.; Caviness, K.; Cicchini, L.; Goodrum, F.
10.1101/2022.11.15.516687 — microbiology — Posted on 2022-11-16
1825 Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence
Jia, X.; Pan, Z.; Yuan, Y.; Luo, B.; Luo, Y.; Mukherjee, S.; Jia, G.; Liu, L.; Ling, X.; Yang, X.; Miao, Z.; Wei, X.; Bujnicki, J. M.; Zhao, K.; Su, Z.
10.1101/2022.11.16.516715 — microbiology — Posted on 2022-11-16
1827 Adaptive archaic introgression related to cellular zinc homeostasis in humans
Roca-Umbert, A.; Garcia-Calleja, J.; Vogel-Gonzalez, M.; Fierro-Villegas, A.; Bosnjak, A.; Ill-Raga, G.; Herrera-Fernandez, V.; Muntane, G.; Campelo, F.; Vicente, R.; Bosch, E.
10.1101/2022.06.29.498106 — evolutionary biology — Posted on 2022-11-16
1831 Episodic memory formation in unrestricted viewing
Nikolaev, A. R.; Bramao, I.; Johansson, R.; Johansson, M.
10.1101/2022.05.24.485821 — neuroscience — Posted on 2022-11-16
1832 A minimal-complexity light-sheet microscope maps network activity in 3D neuronal systems
Wysmolek, P. M.; Kiessler, F. D.; Salbaum, K. A.; Shelton, E. R.; Sonntag, S.; Serwane, F.
10.1101/2022.06.20.496852 — neuroscience — Posted on 2022-11-16
1833 MiR-138-5p upregulation during neuronal maturation parallels with an increase in neuronal survival
Barreda-Manso, M. A.; Soto, A.; Munoz-Galdeano, T.; Reigada, D.; Nieto-Diaz, M.; Maza, R. M.
10.1101/2022.11.15.516547 — neuroscience — Posted on 2022-11-16
1834 Modelling dementia in Drosophila uncovers shared and specific targets of TDP-43 proteinopathy across ALS and FTD relevant circuits
Godfrey, R. K.; Bjork, R. T.; Alsop, E.; Ruvalcaba, H. C.; Antone, J.; Michael, A. F.; Williams, C.; Hala'ufia, G.; Blythe, A. D.; Hall, M.; Van Keuren-Jensen, K.; Zarnescu, D. C.
10.1101/2022.11.16.516763 — neuroscience — Posted on 2022-11-16
1836 Hello darkness, my old friend: 3-Ketoacyl-Coenzyme A Synthase4 is a branch point in the regulation of triacylglycerol synthesis in Arabidopsis
Luzarowska, U.; Russ, A.-K.; Joubes, J.; Batsale, M.; Szymanski, J. J.; Thirumalaikumar, V. P.; Luzarowski, M.; Wu, S.; Zhu, F.; Endres, N.; Khedhayir, S.; Schumacher, J.; Jasinska, W.; Xu, K.; Correa, S. M.; Weil, S.; Skirycz, A.; Fernie, A. R.; Li-Beisson, Y.; Fusari, C. M.; Brotman, Y.
10.1101/2020.07.27.223388 — genetics — Posted on 2022-11-16
1837 SUMOylation regulates Lem2 function in centromere clustering and silencing
Strachan, J.; Leidecker, O.; Spanos, C.; Le Coz, C.; Chapman, E.; Arsenijevic, A.; Zhang, H.; Zhao, N.; Bayne, E. H.
10.1101/2022.11.02.514898 — cell biology — Posted on 2022-11-16
1838 Validation of scRNA-seq by scRT-ddPCR using the example of ErbB2 in MCF7 cells
Lange, T.; Gross, T.; Jeney, A.; Scherzinger, J.; Sinkala, E.; Niemöller, C.; Zimmermann, S.; Koltay, P.; von Stetten, F.; Zengerle, R.; Jeney, C.
10.1101/2022.05.31.494164 — molecular biology — Posted on 2022-11-16
1840 Dynamics of alpha suppression index both modality specific and general attention processes
Clements, G. M.; Gyurkovics, M.; Low, K. A.; Kramer, A. F.; Beck, D. M.; Fabiani, M.; Gratton, G.
10.1101/2022.11.16.516776 — neuroscience — Posted on 2022-11-16
1842 3D reconstruction of the cerebellar germinal layer reveals intercytoplasmic connections between developing granule cells
Cordero Cervantes, D.; Khare, H.; Wilson, A. M.; Mendoza, N. D.; Coulon--Mahdi, O.; Lichtman, J. W.; Zurzolo, C.
10.1101/2022.08.21.504684 — neuroscience — Posted on 2022-11-16
1843 Median eminence myelin continuously turns over in adult mice
Buller, S.; Kohnke, S.; Hansford, R.; Shimizu, T.; Richardson, W. D.; Blouet, C.
10.1101/2022.11.16.516753 — neuroscience — Posted on 2022-11-16
1845 Auditory prediction hierarchy in the human hippocampus and amygdala
Tzovara, A.; Fedele, T.; Sarnthein, J.; Ledergerber, D.; Lin, J. J.; Knight, R. T.
10.1101/2022.11.16.516768 — neuroscience — Posted on 2022-11-16
1847 Functional organization of social perception in the human brain
Santavirta, S.; Karjalainen, T.; Nazari-Farsani, S.; Hudson, M.; Putkinen, V.; Seppala, K.; Sun, L.; Glerean, E.; Hirvonen, J.; Karlsson, H. K.; Nummenmaa, L.
10.1101/2021.12.17.473175 — neuroscience — Posted on 2022-11-16
1848 Transcriptomic and functional mapping of autism associated environmental factors in differentiating human neural progenitors
Arora, A.; Becker, M.; Marques, C.; Oksanen, M.; Li, D.; Mastropasqua, F.; Watts, M. E.; Arora, M.; Falk, A.; Daub, C. O.; Lanekoff, I.; Tammimies, K.
10.1101/2022.06.27.497311 — neuroscience — Posted on 2022-11-16
1849 A systematically optimized awake mouse fMRI paradigm
Xu, W.; Pei, M.; Zhang, K.; Tong, C.; Bo, B.; Feng, J.; Zhang, X.-Y.; Liang, Z.
10.1101/2022.11.16.516376 — neuroscience — Posted on 2022-11-16
1850 Subspace partitioning in human prefrontal cortex resolves cognitive interference
Weber, J.; Iwama, G.; Solbakk, A.-K.; Blenkmann, A. O.; Larsson, P. G.; Ivanovic, J.; Knight, R. T.; Endestad, T.; Helfrich, R.
10.1101/2022.11.16.516719 — neuroscience — Posted on 2022-11-16
1857 Overruled by nature: A plastic response to an ecological regime shift disconnects a gene and its trait
Besnier, F.; Skaala, O.; Wennevik, V.; Ayllon, F.; Utne, K.; Fjeldheim, P. t.; Andersen, K. C.; Knutar, S.; Glover, K. A.
10.1101/2022.10.27.514021 — genetics — Posted on 2022-11-16
1858 Beta-Cyclodextrins as affordable antivirals to treat coronavirus infection
Raich-Regue, D.; Tenorio, R.; Fernandez-de-Castro, I.; Perez-Zsolt, D.; Munoz-Basagoiti, J.; Sachse, M.; Fernandez-Sanchez, S.; Gallemi, M.; Ortega-Gonzalez, P.; Fernandez-Oliva, A.; Gabaldon, J.; Nunez-Delicado, E.; Casas, J.; Tarres, F.; Vergara-Alert, J.; Segales, J.; Carrillo, J.; Blanco, J.; Clotet, B.; Ceron-Carrasco, J.; Izquierdo-Useros, N.; Risco, C.
10.1101/2022.11.16.516726 — microbiology — Posted on 2022-11-16
1860 Molecularly distinct memory CD4+ T cells are induced by SARS-CoV-2 infection and mRNA vaccination
Gray-Gaillard, S. L.; Solis, S.; Monteiro, C.; Chen, H.; Ciabattoni, G.; Samanovic, M. I.; Cornelius, A. R.; Williams, T.; Geesey, E.; Rodriguez, M.; Ortigoza, M. B.; Ivanova, E. N.; Koralov, S. B.; Mulligan, M. J.; Herati, R. S.
10.1101/2022.11.15.516351 — immunology — Posted on 2022-11-16
1861 High-sensitivity vision restoration via ectopic expression of chimeric rhodopsin in mice
Katada, Y.; Yoshida, K.; Serizawa, N.; Kobayashi, K.; Negishi, K.; Hideyuki, O.; Kandori, H.; Tsubota, K.; Kurihara, T.
10.1101/2020.09.17.301523 — neuroscience — Posted on 2022-11-16
1863 The City Nature Challenge - A global citizen science phenomenon contributing to biodiversity knowledge and informing local government practices
Palma, E.; Mata, L.; Cohen, K.; Evans, D.; Gandy, B.; Gaskell, N.; Hatchman, H.; Mezzetti, A.; Neumann, D.; O'Keefe, J.; Shaw, A.; Wells, M.; Williams, L.; Hahs, A. K.
10.1101/2022.11.14.516526 — scientific communication and education — Posted on 2022-11-16
1864 An open-access EEG dataset for speech decoding: Exploring the role of articulation and coarticulation
Moriera, J. P. C.; Carvalho, V. R.; Mendes, E. M. A. M.; Fallah, A.; Sejnowski, T. J.; Lainscsek, C.; Comstock, L. B.
10.1101/2022.11.15.516461 — neuroscience — Posted on 2022-11-16
1867 Exploration of mechanisms of drug resistance by polyaneuploid cancer cells in a microfluidic device and patient tissues
Lim, W.; Hwang, I.; Zhang, J.; Chen, Z.; Jeonghun, J.; Koo, B.-K.; Kim, S.; Lee, J. E.; Pienta, K. j.; Amend, S. R.; Austin, R. H.; Ahn, J.-Y.; Park, S.
10.1101/2022.11.14.515727 — cancer biology — Posted on 2022-11-16
1872 Exome sequencing identifies variants associated with semen quality in Holstein Friesian and Hallikar bulls.
Kunnath, S. K.; Kerekoppa, R.; Katakatelware, M. A.; A, K.; S, J.; D, D.; A, M.; M, J. D.; A, A.; Mall, S.; T S, K. P.
10.1101/2022.11.14.516500 — genomics — Posted on 2022-11-16
1873 Tau polarizes an aging transcriptional signature to excitatory neurons and glia
Wu, T.; Deger, J. M.; Ye, H.; Guo, C.; Dhindsa, J.; Pekarek, B. T.; Al-Ouran, R.; Liu, Z.; Al-Ramahi, I.; Botas, J.; Shulman, J. M.
10.1101/2022.11.14.516410 — genomics — Posted on 2022-11-16
1876 Phenotypic, functional and molecular characterisation of human in vitro-generated IL-17A+ CD8+ T-cells
Gray, E. H.; Srenathan, U.; Durham, L. E.; Lalnunhlimi, S.; Steel, K. J. A.; Catrina, A.; Kirkham, B. W.; Taams, L. S.
10.1101/2022.11.14.516164 — immunology — Posted on 2022-11-16
1877 AhR-mediated activation of innate lymphocytes restrains tissue-resident memory-like CD8+ T cell responses during contact hypersensitivity
Romero-Suarez, S.; Correia, M. P.; Jeong, M.; Ast, V.; Platten, M.; Sexl, V.; Mogler, C.; Cerwenka, A.; Stojanovic, A.
10.1101/2022.11.14.516493 — immunology — Posted on 2022-11-16
1878 Human and murine neutrophils share core transcriptional programs in both homeostatic and inflamed contexts
Hackert, N. S.; Radtke, F. A.; Exner, T.; Lorenz, H.-M.; Mueller-Tidow, C.; Nigrovic, P. A.; Wabnitz, G.; Grieshaber-Bouyer, R.
10.1101/2022.11.13.516246 — immunology — Posted on 2022-11-16
1880 Rational strain design with minimal phenotype perturbation
Narayanan, B.; Weilandt, D. R.; Miskovic, L.; Hatzimanikatis, V.
10.1101/2022.11.14.516382 — systems biology — Posted on 2022-11-16
1885 A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing drugs in RB1-deficient ovarian and breast cancer cells
Bulanova, D.; Akimov, Y.; Senkowski, W.; Oikkonen, J.; Gall-Mas, L.; Timonen, S.; Elmadani, M.; Hynninen, J.; Hautaniemi, S.; Aittokallio, T.; Wennerberg, K.
10.1101/2022.11.14.516369 — cancer biology — Posted on 2022-11-16
1886 A transcriptional response to replication stress selectively expands a subset of BRCA2-mutant mammary epithelial cells
Ghaderi Najafabadi, M.; Gray, G. K.; Kong, L. R.; Gupta, K.; Perera, D.; Brugge, J. S.; Venkitaraman, A.; Shehata, M.
10.1101/2022.11.14.516328 — cancer biology — Posted on 2022-11-16
1888 Application of a Latent Trait Modeling Method for Missing Data Across Datasets: Guidance on Appropriate Factor Structure
bartlett, c.; Gorham, T. J.; Knapp, E. A.; Kress, A. M.; Klamer, B.; Buyske, S.; Lau, B.; Petrill, S. A.
10.1101/2022.11.14.516488 — bioinformatics — Posted on 2022-11-16
1891 The repertoire of copy number alteration signatures in human cancer
Tao, Z.; Wang, S.; Wu, C.; Wu, T.; Zhao, X.; Ning, W.; Wang, G.; Wang, J.; Chen, J.; Diao, K.; Chen, F.; Liu, X.-S.
10.1101/2022.11.14.516412 — bioinformatics — Posted on 2022-11-16
1893 Controlled Hydrogen Sulfide Delivery to Enhance Cell Survival in Bone Tissue Engineering
Ghavimi, S. A. A.; Faulkner, T. J.; Tata, R. R.; Lungren, E. S.; Zhang, R.; Bumann, E. E.; Ulery, B.
10.1101/2022.11.14.516486 — bioengineering — Posted on 2022-11-16
1895 Optimizing bioink composition for human chondrocyte expression of lubricin
Martyniak, K.; Kennedy, S.; Cruz, M. A.; Karimzadeh, M.; Jeon, O.; Alsberg, E.; Kean, T. J.
10.1101/2022.11.14.516490 — bioengineering — Posted on 2022-11-16
1896 Pervasive evolution of tissue-specificity of ancestral genes differentially shaped vertebrates and insects
Mantica, F.; Iniguez, L. P.; Marquez, Y.; Permanyer, J.; Torres-Mendez, A.; Cruz, J.; Franch-Marro, X.; Tulenko, F.; Burguera, D.; Bertrand, S.; Doyle, T.; Nouzova, M.; Currie, P.; Noriega, F. G.; Escriva, H.; Arnone, M. I.; Albertin, C. B.; Wotton, K.; Almudi, I.; Martin, D.; Irimia, M.
10.1101/2022.11.14.516384 — genomics — Posted on 2022-11-16
1897 Genetic architecture of acute hyperthermia resistance in juvenile rainbow trout (Oncorhynchus mykiss) and genetic correlations with production traits
Lagarde, H.; Lallias, D.; Patrice, P.; Prchal, M.; Francois, Y.; D'Ambrosio, J.; Segret, E.; Acin-Perez, A.; Cachelou, F.; Haffray, P.; Dehaullon, A.; Dupont-Nivet, M.; Phocas, F.
10.1101/2022.11.14.516387 — genomics — Posted on 2022-11-16
1899 Somatic Loss of the Y Chromosome and Alzheimer's Disease Risk
Palmer, E. L.; Benchek, P.; Wheeler, N. R.; Smeiszek, S.; Naj, A. C.; Haines, J. L.; Pericak-Vance, M. A.; Forsberg, L. A.; Cukier, H. N.; Song, Y.; Bush, W.
10.1101/2022.11.14.516433 — genetics — Posted on 2022-11-16
1901 Host genomic variation shapes gut microbiome diversity in threespine stickleback fish
Small, C. M.; Beck, E. A.; Currey, M. C.; Tavalire, H. F.; Bassham, S.; Cresko, W. A.
10.1101/2022.11.14.516485 — evolutionary biology — Posted on 2022-11-16
1902 Molecular analyses place the genus Keraunea outside Convolvulaceae
Munoz-Rodriguez, P.; Wood, J. R. I.; Villaescusa Gonzalez, L.; Davis, C. C.; Goodwin, Z. A.; Scotland, R. W.
10.1101/2022.11.14.516456 — evolutionary biology — Posted on 2022-11-16
1906 Blood Transcriptional Correlates of BCG-Induced Protection Against Tuberculosis in Rhesus Macaques
Liu, Y. E.; Darrah, P. A.; Zeppa, J. J.; Kamath, M.; Laboune, F.; Doueck, D. C.; Maiello, P.; Roederer, M.; Flynn, J. L.; Seder, R. A.; Khatri, P.
10.1101/2022.11.14.516343 — immunology — Posted on 2022-11-16
1907 Identification and Characterization of ML321: a Novel and Highly Selective D2 Dopamine Receptor Antagonist with Efficacy in Animal Models that Predict Atypical Antipsychotic Activity
Free, R. B.; Nilson, A. N.; Boldizsar, N. M.; Doyle, T.; Rodriguiz, R. M.; Pogorelov, V. M.; Machino, M.; Lee, K. H.; Bertz, J. W.; Xu, J.; Lim, H. D.; Dulcey, A. E.; Mach, R. H.; Woods, J. H.; Lane, J. R.; Shi, L.; Marugan, J. J.; Wetsel, W. C.; Sibley, D. R.
10.1101/2022.11.14.516475 — pharmacology and toxicology — Posted on 2022-11-16
1908 Context-Aware Transcript Quantification from Long Read RNA-Seq data with Bambu
Chen, Y.; Sim, A. D.; Wan, Y. K.; Yeo, K.; Lee, J. J. X.; Ling, M. H.; Love, M. I.; Goeke, J.
10.1101/2022.11.14.516358 — bioinformatics — Posted on 2022-11-16
1910 Latent factor in Brain RNA-seq studies reflects cell type and clinical heterogeneity
Liu, Z.; Al-Ouran, R.; Liu, C.; Wang, L.; Wan, Y.; Li, X.; Milosavljevic, A.; Shulman, J.
10.1101/2022.11.13.516360 — genomics — Posted on 2022-11-16
1920 FORGEdb: systematic analysis of candidate causal variants to uncover target genes and mechanisms in complex traits.
Breeze, C. E.; Haugen, E.; Gutierrez-Arcelus, M.; Yao, X.; Teschendorff, A.; Beck, S.; Dunham, I.; Stamatoyannopoulos, J.; Franceschini, N.; Machiela, M.; Berndt, S.
10.1101/2022.11.14.516365 — genomics — Posted on 2022-11-16
1923 Cell-type specific developmental defects in PTEN-mutant cortical organoids converge on abnormal circuit activity
Pigoni, M.; Uzquiano, A.; Paulsen, B.; Kedaigle, A. J.; Yang, S. M.; Symvoulidis, P.; Adiconis, X.; Velasco, S.; Sartore, R.; Kim, K.; Tucewicz, A.; Tsafou, K.; Jin, X.; Barrett, L.; Chen, F.; Boyden, E.; Regev, A.; Levin, J. Z.; Arlotta, P.
10.1101/2022.11.15.516664 — neuroscience — Posted on 2022-11-16
1924 Adaptive plasticity in development rate and genetic variance in survival increase the potential for adapting to novel environments
Walter, G. M.; Terranova, D.; la Spina, E.; Majorana, M. G.; Pepe, G.; du Plessis, S.; Clark, J.; Cozzolino, S.; Cristaudo, A. E.; Hiscock, S. J.; Bridle, J. R.
10.1101/2021.02.04.429835 — evolutionary biology — Posted on 2022-11-16
1926 Efficient SARS-CoV-2 detection utilizing chitin-immobilized nanobodies synthesized in Ustilago maydis
Philipp, M.; Müller, L.; Andree, M.; Hussnaetter, K. P.; Schaal, H.; Feldbrügge, M.; Schipper, K.
10.1101/2022.11.11.516239 — molecular biology — Posted on 2022-11-16
1927 Targeted high throughput mutagenesis of the human spliceosome reveals its in vivo operating principles
Beusch, I.; Rao, B.; Studer, M.; Luhovska, T.; Sukyte, V.; Lei, S.; Oses-Prieto, J. A.; SeGraves, E.; Burlingame, A.; Jonas, S.; Madhani, H. D.
10.1101/2022.11.13.516350 — molecular biology — Posted on 2022-11-16
1928 A dynamic epibiont community associated with the bone eating worm Osedax
Goffredi, S.; Panossian, B.; Brzechffa, C.; Field, N.; King, C.; Moggioli, G.; Rouse, G. W.; Martin-Duran, J. M.; Henry, L.
10.1101/2022.11.14.516544 — microbiology — Posted on 2022-11-16
1929 The Src and Abl family kinases activate the Spleen Tyrosine Kinase to maximize phagocytosis and Leishmania infection
Ullah, I.; Barrie, U.; Kernen, R. M.; Mamula, E. T.; Datta, A.; Booshehri, L. M.; Rhodes, E. L.; Bradford, J. M.; Wetzel, D. M.
10.1101/2022.11.14.513575 — microbiology — Posted on 2022-11-16
1930 Functional organization of social perception in the human brain
Santavirta, S.; Karjalainen, T.; Nazari-Farsani, S.; Hudson, M.; Putkinen, V.; Seppala, K.; Sun, L.; Glerean, E.; Hirvonen, J.; Karlsson, H. K.; Nummenmaa, L.
10.1101/2021.12.17.473175 — neuroscience — Posted on 2022-11-16
1931 Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in inbred and recombinant inbred mice
Khan, A. H.; Bagley, J. R.; LaPierre, N.; Gonzalez-Figueroa, C.; Spencer, T. C.; Choudhury, M.; Xiao, X.; Eskin, E.; Jentsch, J. D.; Smith, D. J.
10.1101/2022.11.10.516062 — genetics — Posted on 2022-11-16
1933 Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons
Pietilainen, O.; Trehan, A.; Meyer, D.; Tegtmeyer, M.; Valakh, V.; Gebre, H.; Chen, T.; Vartiainen, E.; Farhi, S. L.; Eggan, K.; McCarroll, S. A.; Nehme, R.
10.1101/2021.09.11.459765 — molecular biology — Posted on 2022-11-16
1934 Control of cell proliferation by memories of mitosis
Meitinger, F.; Davis, R. L.; Martinez, M. B.; Shiau, A. K.; Oegema, K.; Desai, A.
10.1101/2022.11.14.515741 — cancer biology — Posted on 2022-11-16
1935 Design principles of caveolins across metazoa and beyond
Han, B.; Wilson, L. F. L.; Gulsevin, A.; Meiler, J.; Karakas, E.; Kenworthy, A. K.
10.1101/2022.11.15.516482 — biophysics — Posted on 2022-11-16
1937 Age-dependent dysregulation of locus coeruleus firing in a transgenic rat model of Alzheimers disease
Kelberman, M.; Rorabaugh, J. M.; Anderson, C. R.; Marriott, A.; DePuy, S. D.; Rasmussen, K.; McCann, K. E.; Weiss, J. M.; Weinshenker, D.
10.1101/2022.11.15.516661 — neuroscience — Posted on 2022-11-15
1939 Elevated alpha-synuclein attenuates phagocytosis in SNCA triplication human iPSC-derived neuron:microglia co-cultures
Lieberman, R.; Elnaggar, K.; Jesseman, K.; DeFrancisco, S.; Degouveia, K.; Suneby, E.; Wu, H.; Rojas, L. A.; Graef, J. D.
10.1101/2022.11.15.516591 — neuroscience — Posted on 2022-11-15
1940 Food recognition in a blood-feeding insect: characterization of the pharyngeal taste organ
Ortega-Insaurralde, I.; Latorre-Estivalis, J. M.; Costa-da-Silva, A. L.; Cano, A.; Insausti, T.; Morales, H. S.; Pontes, G.; Beron de Astrada, M.; Ons, S.; DeGennaro, M.; Barrozo, R. B.
10.1101/2022.11.15.516640 — neuroscience — Posted on 2022-11-15
1941 Neuroanatomical substrates in Parkinson's Disease psychosis and their association with serotonergic receptor gene expression: A coordinate-based meta-regression analysis.
Pisani, S.; Gunasekera, B.; Lu, Y.; Vignando, M.; ffytche, D.; Aarsland, D.; Chaudhuri, K. R.; Ballard, C.; Lee, J.-Y.; Kim, Y. K.; Velayudhan, L.; Bhattacharyya, S.
10.1101/2022.11.14.516465 — neuroscience — Posted on 2022-11-15
1944 Social Curiosity in Monkeys
Joiner, J. A.; Nair, A. R.; Fagan, N. A.; Chang, S. W. C.
10.1101/2022.11.15.516657 — animal behavior and cognition — Posted on 2022-11-15
1945 Spatiotemporal coordination of stem cell behavior following alveolar injury
Chioccioli, M.; Magruder, S.; McDonough, J. E.; Nouws, J.; Gonzalez, D.; Borriello, L.; Traub, B.; Ye, X.; Hendry, C. E.; Entenberg, D.; Krishnaswamy, S.; Kaminski, N.; Sauler, M.
10.1101/2022.10.28.514255 — cell biology — Posted on 2022-11-15
1947 Evidence for Embracing Normative Modeling
Rutherford, S.; Barkema, P.; Tso, I. F.; Sripada, C.; Beckmann, C. F.; Ruhe, H. G.; Marquand, A. F.
10.1101/2022.11.14.516460 — neuroscience — Posted on 2022-11-15
1953 Thyroid Hormone T4 Mitigates Traumatic Brain Injury via Dynamically Remodeling Cell Type Specific Genes and Pathways
Zhang, G.; Diamante, G.; Ahn, I.; Ying, Z.; Phi, N.; Wang, N.; Arneson, D.; Cely, I.; Gomez-Pinilla, F.; Yang, X.
10.1101/2022.11.15.516648 — neuroscience — Posted on 2022-11-15
1954 When and why grid cells appear or not in trained path integrators
Sorscher, B.; Mel, G. C.; Nayebi, A.; Giocomo, L.; Yamins, D.; Ganguli, S.
10.1101/2022.11.14.516537 — neuroscience — Posted on 2022-11-15
1957 Single-cell RNA sequencing implicates venous endothelial cells as a source of VEGF-mediated neo-angiogenesis in neuroinflammation
Shahriar, S.; Price, M. Z.; Wayne, C. R.; Glendinning, M. D.; Prochilo, G.; Stuhlmann, H.; Biswas, S.; Menon, V.; Agalliu, D.
10.1101/2022.11.15.516660 — neuroscience — Posted on 2022-11-15
1958 UNSUPERVISED HARMONIZATION OF BRAIN MRI USING 3D CYCLE GANS AND ITS EFFECT ON BRAIN AGE PREDICTION
Komandur, D.; Gupta, U.; Chattopadhyay, T.; Dhinagar, N.; Thomopoulos, S. I.; Chen, J.-C.; Beavers, D.; Steeg, G. v.; Thompson, P. M.
10.1101/2022.11.15.516349 — neuroscience — Posted on 2022-11-15
1961 MiR-138-5p upregulation during neuronal maturation parallels with an increase in neuronal survival
Barreda-Manso, M. A.; Soto, A.; Munoz-Galdeano, T.; Reigada, D.; Nieto-Diaz, M.; Maza, R. M.
10.1101/2022.11.15.516547 — neuroscience — Posted on 2022-11-15
1962 Understanding Lesion Progression in a Chronic Model of Cerebral Cavernous Malformations through Combined MRI and Histology
Fisher, D. G.; Sharifi, K. A.; Ulutas, E. Z.; Kumar, J. S.; Kalani, M. Y. S.; Miller, G. W.; Price, R. J.; Tvrdik, P.
10.1101/2022.11.15.516639 — neuroscience — Posted on 2022-11-15
1963 Brain region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
Farsi, Z.; Nicolella, A.; Simmons, S. K.; Aryal, S.; Shepard, N.; Brenner, K.; Lin, S.; Herzog, L. E.; Shin, W.; Gazestani, V.; Song, B.; Bonanno, K.; Keshishian, H.; Carr, S. A.; Macosko, E.; Datta, S. R.; Dejanovic, B.; Kim, E.; Levin, J. Z.; Sheng, M.
10.1101/2022.11.15.516665 — neuroscience — Posted on 2022-11-15
1966 Variation in mate competition favors phenotypic plasticity in male coloration of an African cichlid
Fialkowski, R. J.; Funnell, T. R.; Piefke, T. J.; Border, S. E.; Aufdemberge, P. M.; Hartman, H. A.; Dijkstra, P. D.
10.1101/2022.11.15.516656 — animal behavior and cognition — Posted on 2022-11-15
1968 Conscious perception and the role of the basal ganglia: preliminary findings from a deep brain stimulation study
Boonstra, E. A.; Bais, M. N.; van Schouwenburg, M. R.; van den Munckhof, P.; Smit, D. J. A.; Denys, D.; Slagter, H. A.
10.1101/2022.11.15.516581 — neuroscience — Posted on 2022-11-15
1979 The UBP5 histone H2A deubiquitinase counteracts PRC2-mediated repression to regulate Arabidopsis development and stress responses
Godwin, J.; March, E.; Govindasamy, M.; Bourbousse, C.; Wolff, L.; Fort, A.; Krzyszton, M.; Lopez, J.; Swiezewski, S.; Barneche, F.; Schubert, D.; Farrona, S.
10.1101/2022.11.15.516593 — developmental biology — Posted on 2022-11-15
1980 Pseudomonas aeruginosa mechanosensing controls cell polarity during twitching by activating two antagonistic response regulators
Kuhn, M. J.; Macmillan, H.; Tala, L.; Inclan, Y.; Patino, R.; Pierrat, X.; Al-Mayyah, Z.; Engel, J. N.; Persat, A.
10.1101/2022.11.15.516588 — microbiology — Posted on 2022-11-15
1982 PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum.
Jonsdottir, T. K.; Elsworth, B.; Cobbold, S.; Gabriela, M.; Charnaud, S. C.; Dans, M. G.; Parkyn Schneider, M.; McConville, M.; Bullen, H. E.; Crabb, B. S.; Gilson, P. R.
10.1101/2022.11.15.516562 — microbiology — Posted on 2022-11-15
1984 Subset-specific mitochondrial and DNA damage shapes T cell responses to fever and inflammation
Heintzman, D.; Elasy, J. H.; Chi, C.; Ye, X.; Krystoviak, E.; Khan, W.; Olson, L. M.; Jones, A.; Voss, K.; Patterson, A.; Sugiura, A.; Mason, F. M.; Hong, H.; Bass, L. E.; Beier, K. L.; Deng, W.; Lyssiotis, C. A.; Bick, A. G.; Rathmell, W. K.; Rathmell, J.
10.1101/2022.11.14.516478 — immunology — Posted on 2022-11-15
1986 Live-cell super-resolution imaging of actin using LifeAct-14 with a PAINT-based approach
Bhaskar, H.; Kleinjan, D.-J.; Oi, C.; Gidden, Z.; Rosser, S.; Horrocks, M. H.; Regan, L.
10.1101/2022.11.15.516635 — synthetic biology — Posted on 2022-11-15
1988 Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning
Maasch, J. R. M. A.; Torres, M. D. T.; Melo, M. C. R.; de la Fuente-Nunez, C.
10.1101/2022.11.15.516443 — bioengineering — Posted on 2022-11-15
1989 Aim18p and Aim46p are CHI-domain-containing mitochondrial hemoproteins in Saccharomyces cerevisiae.
Schmitz, J. M.; Wolters, J. F.; Murray, N. H.; Guerra, R. M.; Bingman, C. A.; Hittinger, C. T.; Pagliarini, D. J.
10.1101/2022.11.15.516536 — biochemistry — Posted on 2022-11-15
1990 In-depth specificity profiling of Pro-Pro endopeptidases (PPEPs) using combinatorial synthetic peptide libraries
Claushuis, B.; Cordfunke, R. A.; de Ru, A. H.; Otte, A.; van Leeuwen, H. C.; Klychnikov, O. I.; van Veelen, P. A.; Corver, J.; Drijfhout, J. W.; Hensbergen, P. J.
10.1101/2022.11.15.516584 — biochemistry — Posted on 2022-11-15
1991 A Peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms
Cao, M.; Day, A. M.; Galler, M.; Latimer, H. R.; Byrne, D.; Bennett, E.; Dwyer, E.; Eyers, P. A.; Veal, E. A.
10.1101/2022.11.15.513554 — biochemistry — Posted on 2022-11-15
1992 Highly accurate genome assembly of an improved high-yielding silkworm strain, Nichi01
Waizumi, R.; Tsubota, T.; Jouraku, A.; Kuwazaki, S.; Yokoi, K.; Iizuka, T.; Yamamoto, K.; Sezutsu, H.
10.1101/2022.11.14.516399 — genomics — Posted on 2022-11-15
1995 Expression of retrotransposons contributes to aging in Drosophila
Schneider, B. K.; Sun, S.; Lee, M.; Li, W.; Skvir, N.; Neretti, N.; Vijg, J.; Secombe, J.
10.1101/2022.11.14.516438 — genetics — Posted on 2022-11-15
1997 Improved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq
Schwarzl, T.; Sahadevan, S.; Lang, B.; Miladi, M.; Backofen, R.; Huber, W.; Hentze, M.; Tartaglia, G. G.
10.1101/2022.11.15.516416 — molecular biology — Posted on 2022-11-15
1998 CRISPR-based tools for genetic manipulation in pathogenic Sporothrix species
Hatinguais, R.; Leaves, I.; Brown, G. D.; Brown, A. J. P.; Brock, M.; Peres da Silva, R.
10.1101/2022.11.15.516583 — molecular biology — Posted on 2022-11-15
2001 Peptidyl tRNA hydrolase is required for robust prolyl-tRNA turnover in Mycobacterium tuberculosis
Tomasi, F. G.; Schweber, J. T. P.; Kimura, S.; Zhu, J.; Cleghorn, L. A. T.; Green, S. R.; Davis, S. H.; Waldor, M. K.; Rubin, E. J.
10.1101/2022.11.15.516451 — microbiology — Posted on 2022-11-15
2005 Circuit-specific selective vulnerability in the DMN persists in the face of widespread amyloid burden.
Brunwasser, S. J.; Farris, C.; Elmore, H.; Dyer, E. L.; Nair, K. B.; Whitesell, J. D.; Harris, J. A.; Hengen, K. B.
10.1101/2022.11.14.516510 — neuroscience — Posted on 2022-11-15
2006 Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice
Bedard, M. L.; Lord, J. S.; Perez, P. J.; Bravo, I. M.; Teklezghi, A. T.; Tarantino, L. M.; Diering, G. H.; McElligott, Z. A.
10.1101/2022.04.06.487380 — neuroscience — Posted on 2022-11-15
2007 Microparticle-delivered Cxcl9 prolongs Braf inhibitor efficacy in melanoma
Romano, G.; Paradiso, F.; Li, P.; Shukla, P.; Barger, L. N.; El Naggar, O.; Miller, J. P.; Liang, R. J.; Helms, T. L.; Lazar, A. J.; Wargo, J. A.; Taraballi, F.; Costello, J. C.; Kwong, L. N.
10.1101/2022.05.24.493271 — cancer biology — Posted on 2022-11-15
2010 Identifying strengths and weaknesses of methods for computational network inference from single cell RNA-seq data
McCalla, S. G.; Fotuhi Siahpirani, A.; Li, J.; Pyne, S.; Stone, M.; Periyasamy, V.; Shin, J.; Roy, S.
10.1101/2021.06.01.446671 — bioinformatics — Posted on 2022-11-15
2017 Twist1 and balanced retinoic acid signaling act to suppress cortical folding in mice
Ho-Nguyen, K.-T.; Jain, M.; Matrongolo, M. J.; Ang, P. S.; Schaper, S.; Tischfield, M. A.
10.1101/2022.09.27.509818 — neuroscience — Posted on 2022-11-15
2019 Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior
Benisty, H.; Barson, D.; Moberly, A. H.; Lohani, S.; Coifman, R. R.; Mishne, G.; Crair, M. C.; Cardin, J. A.; Higley, M. J.
10.1101/2021.08.15.456390 — neuroscience — Posted on 2022-11-15
2020 Brassinosteroid gene regulatory networks at cellular resolution
Nolan, T. M.; Vukasinovic, N.; Hsu, C.-W.; Zhang, J.; Vanhoutte, I.; Shahan, R.; Taylor, I. W.; Greenstreet, L.; Heitz, M.; Afanassiev, A.; Wang, P.; Szekely, P.; Brosnan, A.; Yin, Y.; Schiebinger, G.; Ohler, U.; Russinova, E.; Benfey, P. N.
10.1101/2022.09.16.508001 — plant biology — Posted on 2022-11-15
2021 dATP Elevation Induces Myocardial Metabolic Remodeling to Support Improved Cardiac Function
Mhatre, K. N.; Murray, J. D.; Flint, G.; McMillen, T. S.; Weber, G.; Shakeri, M.; Tu, A.-Y.; Steczina, S.; Weiss, R. S.; Marcinek, D.; Murry, C. E.; Raftery, D.; Tian, R.; Moussavi-Harami, F.; Regnier, M.
10.1101/2022.11.07.515235 — physiology — Posted on 2022-11-15
2022 The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
Stewart, H.; Lu, Y.; O'Keefe, S.; Valpadashi, A.; Cruz-Zaragoza, L. D.; Michel, H. A.; Nguyen, S. K.; Carnell, G. W.; Lukhovitskaya, N.; Milligan, R.; Jungreis, I.; Lulla, V.; Davidson, A. D.; Matthews, D. A.; High, S.; Rehling, P.; Emmott, E.; Heeney, J. L.; Edgar, J. R.; Smith, G. L.; Firth, A. E.
10.1101/2022.11.15.516323 — microbiology — Posted on 2022-11-15
2023 Colonisation debt: when invasion history impacts current range expansion
Morel-Journel, T.; Haond, M.; Duan, L.; Mailleret, L.; Vercken, E.
10.1101/2022.11.13.516255 — ecology — Posted on 2022-11-15
2025 Cross-kingdom analysis of microbial communities in Cystic Fibrosis and Bronchiectasis
Cuthbertson, L.; Ish-horowicz, J.; Felton, I.; James, P.; Turek, E.; Cox, M. J.; Loebinger, M. R.; Simmonds, N. J.; Filippi, S. L.; Moffatt, M. F.; Cookson, W. O.
10.1101/2022.01.11.475678 — molecular biology — Posted on 2022-11-15
2026 The microbial composition and functional roles of different kombucha products in Singapore
Hooi, S. L.; Dwiyanto, J.; Toh, K. Y.; Tan, G.; Chong, C. W.; Lee, J. W. J.; Lim, J.
10.1101/2022.11.14.516366 — microbiology — Posted on 2022-11-15
2027 Non-Gaussian Normative Modelling With Hierarchical Bayesian Regression
de Boer, S. A. A.; Kia, S. M.; Rutherford, S.; Zabihi, M.; Fraza, C.; Barkema, P.; Westlye, L. T.; Andreassen, O.; Hinne, M.; Beckmann, C. F.; Marquand, A. F.
10.1101/2022.10.05.510988 — neuroscience — Posted on 2022-11-15
2028 Flexible communication between cell assemblies and 'reader' neurons
Boucly, C. J.; Pompili, M. N.; Todorova, R.; Leroux, E. M.; Wiener, S.; Zugaro, M.
10.1101/2022.09.06.506754 — neuroscience — Posted on 2022-11-15
2029 Excessive self-grooming, gene dysregulation and imbalance between the striosome and matrix compartments in the striatum of Shank3 mutant mice
Ferhat, A.-T.; Biton, A.; Verpy, E.; Forget, B.; de Chaumont, F.; Mueller, F.; Le Sourd, A.-M.; Coqueran, S.; Schmitt, J.; Rochefort, C.; Rondi-Reig, L.; Leboucher, A.; Boland, A.; Fin, B.; Deleuze, J.-F.; Boeckers, T.; Ey, E.; Bourgeron, T.
10.1101/2022.01.19.476922 — neuroscience — Posted on 2022-11-15
2030 Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of diverse feature set
Stein, D.; Sevim Bayrak, C.; Wu, Y.; Kars, M. E.; Stenson, P. D.; Cooper, D. N.; Schlessinger, A.; Itan, Y.
10.1101/2022.06.08.495288 — genetics — Posted on 2022-11-15
2032 The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury
Rogala, S.; Ali, T.; Melissari, M.-T.; Waehrisch, S.; Schuster, P.; Sarre, A.; Boettger, T.; Rogg, E.-M.; Kaur, J.; Krishnan, J.; Dimmeler, S.; Ounzain, S.; Pedrazzini, T.; Herrmann, B. G.; Grote, P.
10.1101/2022.11.14.516395 — developmental biology — Posted on 2022-11-15
2033 Single-molecule analysis of receptor-beta-arrestin interactions in living cells
Grimes, J.; Koszegi, Z.; Lanoiselee, Y.; Miljus, T.; O'Brien, S. L.; Stepniewski, T. M.; Medel-Lacruz, B.; Baidya, M.; Makarova, M.; Owen, D. M.; Shukla, A. K.; Selent, J.; Hill, S. J.; Calebiro, D.
10.1101/2022.11.15.516577 — cell biology — Posted on 2022-11-15
2034 ESYT1 tethers the endoplasmic reticulum to mitochondria and is required for mitochondrial lipid and calcium homeostasis
janer, a.; Morris, J. l.; krols, m.; Antonicka, H.; aaltonen, m. j.; Lin, Z.-Y.; Gingras, A.-C.; Prudent, J.; shoubridge, e. a.
10.1101/2022.11.14.516495 — cell biology — Posted on 2022-11-15
2035 Viral Airway Injury Promotes Cell Engraftment in an In Vitro Model of Cystic Fibrosis Cell Therapy
Lee, R. E.; Mascenik, T. M.; Major, S. C.; Lewis, C. A.; Bear, J. E.; Pickles, R. J.; Randell, S. H.
10.1101/2022.11.14.516213 — cell biology — Posted on 2022-11-15
2037 Type I interferon shapes the distribution and tropism of tick-borne flavivirus
Chotiwan, N.; Rosendal, E.; Willekens, S. M. A.; Schexnaydre, E.; Nilsson, E.; Lindqvist, R.; Hahn, M.; Mihai, I. S.; Morini, F.; Zhang, J.; Ebel, G.; Carlson, L.-A.; Henriksson, J.; Ahlgren, U.; Marcellino, D.; Overby, A. K.
10.1101/2021.11.16.468804 — microbiology — Posted on 2022-11-15
2038 Chromatin states at homeoprotein loci distinguish axolotl limb segments prior to regeneration
Kawaguchi, A.; Wang, J.; Knapp, D.; Murawala, P. M.; Nowoshilow, S.; Masselink, W.; Taniguchi-Sugiura, Y.; Fei, J.; Tanaka, E. M.
10.1101/2022.11.14.516253 — developmental biology — Posted on 2022-11-15
2039 rRNA transcription is integral to liquid-liquid phase separation and maintenance of nucleolar structure
Dash, S.; Lamb, M. C.; Lange, J. J.; McKinney, M. C.; Tsuchiya, D.; Guo, F.; Zhao, X.; Corbin, T. J.; Kirkman, M.; Delventhal, K.; Moore, E. L.; McKinney, S. A.; Shiang, R.; Trainor, P.
10.1101/2022.11.14.516489 — developmental biology — Posted on 2022-11-15
2040 Fisetin Attenuates Cellular Senescence Accumulation During Culture Expansion of Human Adipose-Derived Stem Cells
Mullen, M. T.; Goff, A.; Billings, J.; Kloser, H.; Huard, C.; Mitchell, J.; Hambright, W. S.; Ravuri, S.; Huard, J.
10.1101/2022.11.15.516580 — cell biology — Posted on 2022-11-15
2041 Transcription regulates bleb formation and stability independent of nuclear rigidity
Berg, I. K.; Currey, M. L.; Gupta, S.; Berrada, Y.; Nyugen Viet, B.; Pho, M.; Patteson, A. E.; Schwarz, J.; Banigan, E. J.; Stephens, A. D.
10.1101/2022.11.14.516344 — cell biology — Posted on 2022-11-15
2042 The GxcM-Fbp17/RacC-WASP signaling cascade regulates polarized cortex assembly in migrating cells
Li, D.; Yang, Y.; Wang, Y.; Chao, X.; Huang, J.; Singh, S. P.; Zhang, C.; Lou, J.; Gao, P.; Huang, S.; Cai, H.
10.1101/2022.11.14.515780 — cell biology — Posted on 2022-11-15
2043 Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation
Li, T. Y.; Wang, Q.; Gao, A. W.; Li, X.; Mottis, A.; Shong, M.; Auwerx, J.
10.1101/2022.11.14.516427 — cell biology — Posted on 2022-11-15
2046 Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-causing mutations
Hussein, Y.; Tripathi, U.; Choudhary, A.; Nayak, R.; Peles, D.; Rosh, I.; Djamus, J.; Spiegel, R.; Garin-Shkolnik, T.; Stern, S.
10.1101/2022.11.02.514882 — neuroscience — Posted on 2022-11-15
2048 Cerebrovascular damage caused by the gut microbe-derived uraemic toxin p-cresol sulfate isprevented by blockade of the epidermal growth factor receptor
Shah, S. N.; Knausenberger, T. B.-A.; Connell, E.; Le Gall, G.; Hardy, T. A.; Randall, D. W.; McCafferty, K.; Yaqoob, M. M.; Solito, E.; Müller, M.; Stachulski, A. V.; Glen, R. C.; Vauzour, D.; Hoyles, L.; McArthur, S.
10.1101/2022.11.12.516113 — systems biology — Posted on 2022-11-15
2054 Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma
Dolgalev, I.; Zhou, H.; Shenker-Tauris, N.; Le, H.; Sakellaropoulos, T.; Coudray, N.; Zhu, K.; Vasudevaraja, V.; Yeaton, A.; Goparaju, C. V.; Li, Y.; Sulaiman, I.; Tsay, J.-C. J.; Meyn, P.; Mohamed, H.; Sydney, I.; Ramaswami, S.; Narula, N.; Kulicke, R.; Davis, F. P.; Stransky, N.; Smolen, G. A.; Cheng, W.-Y.; Cai, J.; Punekar, S.; Velcheti, V.; Poirier, J. T.; Neel, B.; Wong, K.-K.; Chiriboga, L.; Heguy, A.; Papagiannakopoulos, T.; Snuderl, M.; Segal, L. N.; Moreira, A. L.; Pass, H. I.; Tsirigos, A.
10.1101/2022.11.10.516003 — bioinformatics — Posted on 2022-11-15
2056 Multiscale model of the different modes of cancer cell invasion
Ruscone, M.; Montagud, A.; Chavrier, P.; Destaing, O.; Bonnet, I.; Zinovyev, A.; Barillot, E.; Noel, V.; Calzone, L.
10.1101/2022.10.07.511296 — bioinformatics — Posted on 2022-11-15
2057 Decoding the Variant-to-Function Relationship for LIPA, a Risk Locus for CAD
Li, F.; Flynn, E.; Shi, J.; Wu, X.; Wang, Z.; Xue, C.; Cheng, H.; Meng, Y.; Cui, J.; Zhu, Y.; Rozenblyum, A.; Chun, J.; Hernandez-Ono, A.; Razani, B.; Westerterp, M.; Bauer, R. C.; Suh, Y.; Hao, K.; Lappalainen, T.; Zhang, H.
10.1101/2022.11.12.516293 — genomics — Posted on 2022-11-15
2058 Genome-Wide Association Study Finds Multiple Loci Associated with Intraocular Pressure in HS Rats
Fowler, S.; Wang, T.; Munro, D.; Kumar, A.; Chitre, A. S.; Hollingsworth, T.; Martinez, A. G.; St. Pierre, C. L.; Bimschleger, H.; Gao, J.; Cheng, R.; Mohammadi, P.; Chen, H.; Palmer, A. A.; Polesskaya, O.; Jablonski, M. M.
10.1101/2022.08.16.503865 — genomics — Posted on 2022-11-15
2059 Time-Aligned Hourglass Gastrulation Models in Rabbit and Mouse
Mayshar, Y.; Raz, O.; Cheng, S.; Ben-Yair, R.; Hadas, R.; Reines, N.; Mittnenzweig, M.; Ben-Kiki, O.; Lifshitz, A.; Tanay, A.; Stelzer, Y.
10.1101/2022.11.13.516304 — evolutionary biology — Posted on 2022-11-15
2060 Diverging trends and drivers of Arctic flower production over space and time
Becker-Scarpitta, A.; Antao, L. H.; Martin Schmidt, N.; Blanchet, G. F.; Kaarlejärvi, E.; Raundrup, K.; Roslin, T.
10.1101/2022.11.15.516565 — ecology — Posted on 2022-11-15
2062 IL-11 disrupts alveolar epithelial progenitor function
Kortekaas, R. K.; Geillinger-Kaestle, K. E.; Borghuis, T.; Belharch, K.; Webster, M.; Timens, W.; Burgess, J. K.; Gosens, R.
10.1101/2022.11.11.516088 — cell biology — Posted on 2022-11-15
2063 Fibroblast-expressed LRRC15 suppresses SARS-CoV-2 infection and controls antiviral and antifibrotic transcriptional programs.
Loo, L.; Waller, M. A.; Moreno, C. L.; Cole, A. J.; Stella, A. O.; Pop, O.-T.; Jochum, A.-K.; Ali, O. H.; Denes, C. E.; Hamoudi, Z.; Chung, F.; Aggarwal, A.; Low, J. K. K.; Patel, K.; Siddique, R.; Kang, T.; Mathivanan, S.; Mackay, J.; Flatz, L.; Turville, S.; Hesselson, D.; Neely, G. G.
10.1101/2021.11.09.467981 — cell biology — Posted on 2022-11-15
2065 The tissue-specific autophagic response to nutrient deprivation
Yang, Y. J.; Grosso Jasutkar, H.; Griffey, C. J.; Kim, K.; Melia, T.; Dephoure, N.; Yamamoto, A.
10.1101/2022.11.12.516287 — physiology — Posted on 2022-11-15
2071 Discovery and validation of the binding poses of allosteric fragment hits to PTP1b: From molecular dynamics simulations to X-ray crystallography
Greisman, J. B.; Willmore, L.; Yeh, C. Y.; Giordanetto, F.; Shahamadtar, S.; Nisonoff, H.; Maragakis, P.; Shaw, D. E.
10.1101/2022.11.14.516467 — biophysics — Posted on 2022-11-15
2072 Tumor proliferation and invasion are coupled through cell-extracellular matrix friction
Crawford, A. J.; Gomez-Cruz, C.; Russo, G. C.; Huang, W.; Bhorkar, I.; Munoz-Barrutia, A.; Wirtz, D.; Garcia-Gonzalez, D.
10.1101/2022.11.15.516548 — biophysics — Posted on 2022-11-15
2075 Identification of variation in Fibromelanosis region on chromosome 20 for determining the purity of Indonesian Cemani chicken
Dharmayanthi, A. B.; Kinoshita, K.; Khaerunnisa, I.; Safitry, R. S.; Iryanto, S. B.; Yohanna, ; Sutikno, ; Ishak, A. B. L.; Zein, M. S. A.; Satta, Y.; Akiyama, T.; Sumantri, C.
10.1101/2022.11.13.516295 — genetics — Posted on 2022-11-15
2076 Colonisation debt: when invasion history impacts current range expansion
Morel-Journel, T.; Haond, M.; Duan, L.; Mailleret, L.; Vercken, E.
10.1101/2022.11.13.516255 — ecology — Posted on 2022-11-15
2078 Decoding gene regulation in the mouse embryo using single-cell multi-omics
Argelaguet, R.; Lohoff, T.; Li, J. G.; Nakhuda, A.; Drage, D.; Krueger, F.; Velten, L.; Clark, S. J.; Reik, W.
10.1101/2022.06.15.496239 — developmental biology — Posted on 2022-11-15
2079 Systematic identification and characterization of novel genes in the regulation and biogenesis of photosynthetic machinery
Kafri, M.; Patena, W.; Martin, L.; Wang, L.; Gomer, G.; Sirkejyan, A. K.; Goh, A.; Wilson, A. T.; Gavrilenko, S. E.; Breker, M.; Roichman, A.; McWhite, C. D.; Rabinowitz, J. D.; Cross, F. R.; Wuhr, M.; Jonikas, M. C.
10.1101/2022.11.12.515357 — cell biology — Posted on 2022-11-15
2080 Nanoscopy of organelles and tissues with iterative ultrastructure expansion microscopy (iU-ExM)
Louvel, V.; Haase, R.; Mercey, O.; Laporte, M. H.; Soldati-Favre, D.; Hamel, V.; Guichard, P.
10.1101/2022.11.14.516383 — cell biology — Posted on 2022-11-15
2081 Promoter-adjacent DNA hypermethylation can downmodulate gene expression: TBX15 in the muscle lineage
Ehrlich, K. C.; Lacey, M.; Baribault, C.; Sen, S.; Olivier Esteve, P.; Pradhan, S. C.; Ehrlich, M.
10.1101/2022.11.14.516527 — molecular biology — Posted on 2022-11-15
2082 Incorporating Pre-training Paradigm for Antibody Sequence-Structure Co-design
Gao, K.; Wu, L.; Zhu, J.; Peng, T.; Xia, Y.; He, L.; Xie, S.; Qin, T.; Liu, H.; He, K.; Liu, T.-Y.
10.1101/2022.11.14.516404 — molecular biology — Posted on 2022-11-15
2084 The nanomechanical fingerprint of colorectal-derived peritoneal metastasis
Lorenc, E.; Varinelli, L.; Chighizola, M.; Brich, S.; Pisati, F.; Guaglio, M.; Baratti, D.; Deraco, M.; Gariboldi, M.; Podesta, A.
10.1101/2022.08.17.504271 — biophysics — Posted on 2022-11-15
2085 Molecular Dynamics guided Brownian tomography of apoferritin in liquid water
Acosta-Gutierrez, S.; De Pace, C.; Ing, G.; Marchello, G.; Wilkinson, N.; Gervasio, F.; Ruiz-Perez, L.; Battaglia, G.
10.1101/2021.04.30.442083 — biophysics — Posted on 2022-11-15
2086 FASSO: An AlphaFold based method to assign functional annotations by combining sequence and structure orthology
Andorf, C. M.; Sen, S.; Hayford, R. K.; Portwwod, J. L.; Cannon, E. K.; Harper, L. C.; Gardiner, J. M.; Sen, T. Z.; Woodhouse, M. R.
10.1101/2022.11.10.516002 — bioinformatics — Posted on 2022-11-15
2087 Formation process of the twinning β-form anhydrous guanine platelets in the scallop eyes
Guo, D.; Liu, Y.; Hou, X.; Wang, X.; Fan, C.; Bao, L.; He, X.; Zhang, H.; Ma, Y.
10.1101/2022.11.14.516375 — biochemistry — Posted on 2022-11-15
2088 Characterisation of fasting and postprandial NMR metabolites: insights from the ZOE PREDICT 1 Study
Bermingham, K. M.; Mazidi, M.; Franks, P. W.; Maher, T.; Valdes, A. M.; Linenberg, I.; Wolf, J.; Hadjigeorgiou, G.; Spector, T. D.; Menni, C.; Ordovas, J. M.; Berry, S. E.; Hall, W. L.
10.1101/2022.11.14.516406 — biochemistry — Posted on 2022-11-15
2090 Regulation of ATAD2B bromodomain binding activity by the histone code
Phillips, M.; Quinn, K.; Paculova, H.; Montgomery, C.; Joseph, F. M.; Boyson, S. P.; Chang, S.; Nix, J. C.; Young, N. L.; Frietze, S. E.; Glass, K. C.
10.1101/2022.11.14.516501 — biochemistry — Posted on 2022-11-15
2095 Targeting long non-coding RNA NUDT6 enhances smooth muscle cell survival and limits vascular disease progression
Winter, H.; Winski, G.; Busch, A.; Chernogubova, E.; Fasolo, F.; Wu, Z.; Backlund, A.; Khomtchouk, B. B.; Van Booven, D.; Sachs, N.; Eckstein, H.-H.; Wittig, I.; Boon, R. A.; Jin, H.; Maegdefessel, L.
10.1101/2022.11.14.516372 — molecular biology — Posted on 2022-11-15
2096 Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti
Merkling, S. H.; Crist, A. B.; Henrion-Lacritick, A.; Frangeul, L.; Gausson, V.; Blanc, H.; Baidaliuk, A.; Saleh, M.-C.; Lambrechts, L.
10.1101/2022.11.14.516413 — microbiology — Posted on 2022-11-15
2097 Diversified repertoire of phage defenses in Klebsiella pneumoniae: Bi-directional steering effects impacting antibiotic susceptibility
Nang, S. C.; Lu, J.; Yu, H.; Wickremasinghe, H.; Azad, M. A. K.; Han, M.; Zhao, J.; Rao, G.; Bergen, P. J.; Velkov, T.; Sherry, N.; McCarthy, D. T.; Aslam, S.; Schooley, R. T.; Howden, B. P.; Barr, J. J.; Zhu, Y.; Li, J.
10.1101/2022.11.14.516531 — microbiology — Posted on 2022-11-15
2099 Distributed Compact Plasma Reactor Sterilization for Planetary Protection in Space Missions
Choudhury, B.; Revazishvili, T.; Roy, S.; Lozada, M.; Roy, S.; Mastro, E.; Portugal, S.
10.1101/2022.11.14.516453 — microbiology — Posted on 2022-11-15
2104 Septins and K63 chains form separate bacterial microdomains during autophagy of entrapped Shigella
Lobato-Marquez, D.; Conesa, J. J.; Lopez-Jimenez, A. T.; Divine, M. E.; Pruneda, J. N.; Mostowy, S.
10.1101/2022.11.14.516380 — microbiology — Posted on 2022-11-15
2106 De novo design of modular peptide binding proteins by superhelical matching
Wu, K.; Bai, H.; Chang, Y.-T.; Redler, R.; McNally, K. E.; Sheffler, W.; Brunette, T.; Hicks, D. R.; Morgan, T. E.; Stevens, T. J.; Broerman, A.; Goreshnik, I.; DeWitt, M.; Chow, C. M.; Shen, Y.; Stewart, L.; Derivery, E.; Silva, D. A.; Bhabha, G.; Ekiert, D.; Baker, D.
10.1101/2022.11.14.514089 — biochemistry — Posted on 2022-11-15
2109 The microbial composition and functional roles of different kombucha products in Singapore
Hooi, S. L.; Dwiyanto, J.; Toh, K. Y.; Tan, G.; Chong, C. W.; Lee, J. W. J.; Lim, J.
10.1101/2022.11.14.516366 — microbiology — Posted on 2022-11-15
2111 Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation
Goers, L.; Kim, K.; Canning, P. J.; Stedman, T. C.; Mou, X.; Heinz Ernst, N.; Coers, J.; lesser, c. F.
10.1101/2022.11.14.516511 — microbiology — Posted on 2022-11-15
2112 Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting Mycobacterium tuberculosis
Roy, S.; Berida, T.; McKee, S. R.; Chatterjee, S.; Li, W.; Pandey, P.; Tripathi, S. K.; Doerksen, R. J.; Jackson, M.; Ducho, C.; Stallings, C. L.
10.1101/2022.11.14.516356 — microbiology — Posted on 2022-11-15
2115 Field dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging
Fu, S.; Shi, W.; Luo, T.; He, Y.; Zhou, L.; Yang, J.; Yang, Z.; Liu, J.; Liu, X.; Guo, Z.; Yang, C.; Liu, C.; Huang, Z.-l.; Ries, J.; Zhang, M.; Xi, P.; Jin, D.; Li, Y.
10.1101/2022.10.14.512179 — biophysics — Posted on 2022-11-15
2117 Identification of a sensory neuron Cav2.3 inhibitor within a new superfamily of macro-conotoxins
Hackney, C. M.; Florez Salcedo, P.; Mueller, E.; Kjelgaard, L. D.; Watkins, M.; Zachariassen, L. G.; Tuelung, P. S.; McArthur, J. R.; Adams, D. J.; Kristensen, A. S.; Olivera, B.; Finol-Urdaneta, R. K.; Safavi, H.; Morth, J. P.; Ellgaard, L.
10.1101/2022.07.04.498665 — biochemistry — Posted on 2022-11-15
2118 Novel Methods for Multi-ancestry Polygenic Prediction and their Evaluations in 5.1 Million Individuals of Diverse Ancestry
Zhang, H.; Zhan, J.; Jin, J.; Lu, W.; Zhao, R.; Ahearn, T. U.; Yu, Z.; O'Connell, J.; Jiang, Y.; Chen, T.; Okuhara, D.; 23andMe Research Team, ; Garcia-Closas, M.; Lin, X.; Koelsch, B. L.; Chatterjee, N.
10.1101/2022.03.24.485519 — genetics — Posted on 2022-11-15
2121 IL-11 disrupts alveolar epithelial progenitor function
Kortekaas, R. K.; Geillinger-Kaestle, K. E.; Borghuis, T.; Belharch, K.; Webster, M.; Timens, W.; Burgess, J. K.; Gosens, R.
10.1101/2022.11.11.516088 — cell biology — Posted on 2022-11-15
2124 CAR modulates plasma membrane nano-organization and immune signaling downstream of RALF1-FERONIA signaling pathway
Chen, W.; Zhou, H.; Xu, F.; Yu, M.; Coego, A.; Rodriguez, L.; Lu, Y.; Xie, Q.; Fu, Q.; Chen, J.; Xu, G.; Wu, D.; Li, X.; Li, X.; Jaillais, Y.; Rodriguez, P. L.; Zhu, S.; Yu, F.
10.1101/2021.10.13.464316 — plant biology — Posted on 2022-11-15
2125 Vernalization-triggered expression of the antisense transcript COOLAIR is mediated by CBF genes
Jeon, M.; Jeong, G.; Yang, Y.; Luo, X.; Jeong, D.; Hyun, Y.; Kyung, J.; He, Y.; Lee, I.
10.1101/2021.10.07.463455 — plant biology — Posted on 2022-11-15
2126 mb-PHENIX: Diffusion and Supervised Uniform Manifold Approximation for denoising microbiota data
Padron-Manrique, C.; Vazquez-Jimenez, A.; Esquivel-Hernandez, D. A.; Martinez-Lopez, Y. E.; Neri-Rosario, D.; Sanchez, J. P.; Giron-Villalobos, D.; Resendis-Antonio, O.
10.1101/2022.06.23.497285 — bioinformatics — Posted on 2022-11-15
2129 Single cell profiling reveals strain-specific differences in myeloid inflammatory potential in the rat liver
Pouyabahar, D.; Chung, S. W.; Pezzutti, O. I.; Perciani, C. T.; Wang, X.; Ma, X.-Z.; Jiang, C.; Camat, D.; Chung, T.; Sekhon, M.; Manuel, J.; Chen, X.-C.; McGilvray, I. D.; MacParland, S.; Bader, G.
10.1101/2022.11.11.516225 — genomics — Posted on 2022-11-14
2131 Robustness of a multivariate composite score when evaluating distress of animal models for gastrointestinal diseases
Talbot, S. R.; Kumstel, S.; Schulz, B.; Tang, G.; Abdelrahman, A.; Seume, N.; Wendt, E. H. U.; Eichberg, J.; Hager, C.; Bleich, A.; Vollmar, B.; Zechner, D.
10.1101/2022.11.14.516441 — animal behavior and cognition — Posted on 2022-11-14
2132 Quantification of Early Gait Development: Expanding the Application of Catwalk Technology to an Infant Rhesus Macaque Model
Kabakov, S. A.; Crary, E.; Menna, V.; Razo, E. R.; Eickhoff, J. C.; Dulaney, N. R.; Drew, J. R.; Bach, K.; Poole, A. M.; Stumpf, M.; Mitzey, A. M.; Malicki, K. B.; Schotzko, M. L.; Pickett, K. A.; Schultz-Darken, N. J.; Emborg, M. E.; O'Connor, D. H.; Golos, T. G.; Mohr, E. L.; Ausderau, K. K.
10.1101/2022.11.14.516450 — animal behavior and cognition — Posted on 2022-11-14
2134 Epigenetic age acceleration predicts subject-specific white matter degeneration in the human brain.
Newman, B. T.; Danoff, J. S.; Lynch, M. E.; Giamberardino, S.; Gregory, S. G.; Connelly, J. J.; Druzgal, T. J.; Morris, J. P.
10.1101/2022.11.14.516491 — neuroscience — Posted on 2022-11-14
2141 Sex-Specific Changes in Neuronal Activity and Affective Behavior after Chronic Alcohol Consumption in CRF1-cre Transgenic Rats
Quadir, S. G.; Arleth, G. M.; Cone, M. G.; High, M. W.; Ramage, M. C.; Effinger, D. P.; Echeveste Sanchez, M.; Herman, M. A.
10.1101/2022.11.14.516444 — neuroscience — Posted on 2022-11-14
2143 Cortical reactivations predict future sensory responses
Nguyen, N. D.; Lutas, A.; Fernando, J.; Vergara, J.; McMahon, J.; Dimidschstein, J.; Andermann, M. L.
10.1101/2022.11.14.516421 — neuroscience — Posted on 2022-11-14
2145 An MR-based brain template and atlas for optical projection tomography and light sheet fluorescence microscopy
Willekens, S. M.; Morini, F.; Mediavilla, T.; Nilsson, E.; Oradd, G.; Hahn, M.; Chotiwan, N.; Visa Majoral, M.; Berggren, P.-O.; Ilegems, E.; Overby, A. K.; Ahlgren, U.; Marcellino, D.
10.1101/2022.11.14.516420 — neuroscience — Posted on 2022-11-14
2146 Ketone ester-enriched diet ameliorates motor and dopamine release deficits in MitoPark mice
Mahajan, V. R.; Nadel, J. A.; King, M. T.; Pawlosky, R. J.; Davis, M. I.; Veech, R. L.; Lovinger, D. M.; Salinas, A.
10.1101/2022.11.14.516368 — neuroscience — Posted on 2022-11-14
2152 A consensus score to combine inferences from multiple centres
Haselimashhadi, H.; Babalola, K.; Wilson, R.; Groza, T.; Munoz-Fuentes, V.
10.1101/2022.11.10.515944 — bioinformatics — Posted on 2022-11-14
2162 Species-conserved mechanisms of cognitive flexibility in complex environments
Baehner, F.; Popov, T.; Hermann, S.; Boehme, N.; Merten, T.; Zingone, H.; Koppe, G.; Meyer-Lindenberg, A.; Toutounji, H.; Durstewitz, D.
10.1101/2022.11.14.516439 — neuroscience — Posted on 2022-11-14
2163 Circuit-specific selective vulnerability in the DMN persists in the face of widespread amyloid burden.
Brunwasser, S. J.; Farris, C.; Elmore, H.; Dyer, E. L.; Nair, K. B.; Whitesell, J. D.; Harris, J. A.; Hengen, K. B.
10.1101/2022.11.14.516510 — neuroscience — Posted on 2022-11-14
2164 The GLM-Spectrum: A multilevel framework for spectrum analysis with covariate and confound modelling
Quinn, A. J.; Atkinson, L. Z.; Gohil, C.; Kohl, O.; Pitt, J.; Zich, C.; Nobre, A. C.; Woolrich, M. W.
10.1101/2022.11.14.516449 — neuroscience — Posted on 2022-11-14
2168 Using large-scale whole-genome sequence data for single-step genomic predictions in maternal and terminal pig lines
Jang, S.; Ros-Freixedes, R.; Hickey, J. M.; Chen, C.-Y.; Herring, W.; Misztal, I.; Lourenco, D.
10.1101/2022.11.11.516229 — genomics — Posted on 2022-11-14
2174 Genetic pathways regulating the longitudinal acquisition of cocaine self administration in mice
Khan, A. H.; Bagley, J. R.; LaPierre, N.; Gonzalez-Figueroa, C.; Spencer, T. C.; Choudhury, M.; Xiao, X.; Eskin, E.; Jentsch, J. D.; Smith, D. J.
10.1101/2022.11.10.516062 — genetics — Posted on 2022-11-14
2181 An RFX transcription factor regulated ciliogenesis in the progenitors of choanoflagellates and animals
Coyle, M.; Tajima, A.; Leon, F.; Choksi, S. P.; Yang, A.; Espinoza, S.; Hughes, T. R.; Reiter, J. F.; Booth, D. S.; King, N.
10.1101/2022.11.11.515474 — evolutionary biology — Posted on 2022-11-14
2183 Genome-wide association study highlights escape from aphids by delayed growth in Arabidopsis thaliana
Xu, C.; Sato, Y.; Yamazaki, M.; Brasser, M.; Barbour, M. A.; Bascompte, J.; Shimizu, K. K.
10.1101/2022.11.10.515564 — ecology — Posted on 2022-11-14
2184 Selective brain cooling monitored by CT perfusion as adjuvant therapy in a porcine model of severe ischemic stroke
Tong, O. L. H.; Chung, K. J.; Hadway, J.; Morrison, L.; Desjardins, L.; Tyler, S.; Flamminio, M.; Keenliside, L.; Lee, T.-Y.
10.1101/2022.11.11.516055 — neuroscience — Posted on 2022-11-14
2191 Comparison of machine learning to deep learning for automated annotation of Gleason patterns in whole mount prostate cancer histology.
Duenweg, S. R.; Brehler, M.; Bobholz, S. A.; Lowman, A. K.; Winiarz, A.; Kyereme, F.; Nencka, A.; Iczkowski, K. A.; LaViolette, P.
10.1101/2022.11.10.516007 — pathology — Posted on 2022-11-14
2192 Nucleation of Biomolecular Condensates from Finite-Sized Simulations
Li, L.; Paloni, M.; Finney, A. R.; Barducci, A.; Salvalaglio, M.
10.1101/2022.11.11.515961 — biophysics — Posted on 2022-11-14
2199 OpenMEA: Open-Source Microelectrode Array Platform for Bioelectronic Interfacing
O'Leary, G. M.; Khramtsov, I.; Ramesh, R.; Perez-Ignacio, A.; Shah, P.; Moradi Chameh, H.; Gierlach, A.; Genov, R.; Valiante, T.
10.1101/2022.11.11.516234 — bioengineering — Posted on 2022-11-14
2200 From Pigs to Silkworms: Cognition and Welfare across 10 Farmed Taxa
Miller, R.; Schiestl, M.; Trevarthen, A.; Gaffney, L.; Lavery, J. M.; Fischer, B.; Schnell, A.
10.1101/2022.11.11.516141 — animal behavior and cognition — Posted on 2022-11-14
2202 DrFARM: Identification and inference for pleiotropic gene in GWAS
Chan, L. S.; Li, G.; Fauman, E. B.; Laakso, M.; Boehnke, M.; Song, P. X. K.
10.1101/2022.11.10.515671 — genomics — Posted on 2022-11-14
2203 PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry
Burley, K. L.; Fitzgibbon, L.; van Heel, D. A.; Vuckovic, D.; Mumford, A.
10.1101/2022.11.11.516129 — genomics — Posted on 2022-11-14
2207 Multi-omic spatial profiling reveals the unique virus-driven immune landscape of COVID-19 placentitis
Pugh, M.; Fennel, E.; Leahy, C. I.; Perry, T.; Hargitai, B.; Marton, T.; Hunter, K. J.; Halford, G.; Yilmaz, H. O.; Stamataki, Z.; Reynolds, G.; Hill, H. J.; Willcox, B. E.; Steven, N. M.; Thornton, C. A.; Dojcinov, S.; Culhane, A.; Murray, P. G.; Taylor, G. S.
10.1101/2022.11.14.516398 — immunology — Posted on 2022-11-14
2208 Genetic and structural data on the SARS-CoV-2 Omicron BQ.1 variant reveal its low potential for epidemiological expansion
Scarpa, F.; Sanna, D.; Benvenuto, D.; Borsetti, A.; Azzena, I.; Casu, M.; Fiori, P. L.; Giovanetti, M.; Maruotti, A.; Ceccarelli, G.; Caruso, A.; Caccuri, F.; Cauda, R.; Cassone, A.; Pascarella, S.; Ciccozzi, M.
10.1101/2022.11.11.516052 — molecular biology — Posted on 2022-11-14
2210 Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses
Radic, L.; Sliepen, K.; Yin, V.; Brinkkemper, M.; Capella-Pujol, J.; Schriek, A. I.; Torres, J. L.; Bangaru, S.; Burger, J. A.; Poniman, M.; Bontjer, I.; Bouhuijs, J. H.; Gideonse, D.; Eggink, D.; Ward, A. B.; Heck, A. J. R.; van Gils, M. J.; Sanders, R. W.; Schinkel, J.
10.1101/2022.11.11.516125 — immunology — Posted on 2022-11-14
2212 Single-cell gene expression and chromatin accessibility profiling of human pancreatic islets at basal and stimulatory conditions nominates mechanisms of type 1 diabetes genetic risk
D'Oliveira Albanus, R.; Tang, X.; Taylor, H. J.; Manickam, N.; Erdos, M.; Narisu, N.; Han, Y.; Orchard, P.; Varshney, A.; Liu, C.; Naji, A.; HPAP Consortium, ; Collins, F. S.; Chen, S.; Parker, S. C. J.
10.1101/2022.11.12.516291 — genomics — Posted on 2022-11-14
2214 Targeting IRS-1/2 in uveal melanoma inhibits in vitro cell growth, survival and migration, and in vivo tumor growth.
Chattopadhyay, C.; Bhattacharya, R.; Roszik, J.; Khan, F.; Wells, G. A.; Villanueva, H.; Qin, Y.; Bhattacharya, R.; Patel, S.; Grimm, E. A.
10.1101/2022.10.26.513928 — cell biology — Posted on 2022-11-14
2215 A new LD protein, ApoL6 disrupts the Perilipin 1-HSL interaction to inhibit lipolysis
Wang, Y.; Nguyen, H. P.; Xue, P.; Xie, Y.; Yi, D.; Lin, F.; Viscarra, J. A.; Ibe, N. U.; Duncan, R. E.; Sul, H. S.
10.1101/2022.11.10.516022 — molecular biology — Posted on 2022-11-14
2216 Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans
Gusa, A.; Yadav, V.; Roth, C.; Williams, J. D.; Shouse, E. M.; Magwene, P. M.; Heitman, J.; Jinks-Robertson, S.
10.1101/2022.06.10.495668 — microbiology — Posted on 2022-11-14
2217 Oxygen concentration modulates colibactin production
Bossuet-Greif, N.; Guyonnet, C.; Chagneau, C.; Tang-Fichaux, M.; Penary, M.; Loubet, D.; Branchu, P.; Oswald, E.; Nougayrede, J.-P.
10.1101/2022.06.20.496773 — microbiology — Posted on 2022-11-14
2219 Measuring brain critical dynamics to inform Brain-Computer Interfaces
Corsi, M.-C.; Sorrentino, P.; Schwartz, D.; George, N.; Hugueville, L.; Kahn, A. E.; Dupont, S.; Bassett, D. S.; Jirsa, V.; De Vico Fallani, F.
10.1101/2022.06.14.495887 — neuroscience — Posted on 2022-11-14
2220 Plants cope with fluctuating light by frequency-dependent non-photochemical quenching and cyclic electron transport
Niu, Y.; Lazar, D.; Holzwarth, A. R.; Kramer, D. M.; Matsubara, S.; Fiorani, F.; Poorter, H.; Schrey, S. D.; Nedbal, L.
10.1101/2022.02.09.479783 — plant biology — Posted on 2022-11-14
2221 Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2
Loschwitz, J.; Steffens, N.; Wang, X.; Schaeffler, M.; Pfeffer, K.; Degrandi, D.; Strodel, B.
10.1101/2022.04.27.489784 — biophysics — Posted on 2022-11-14
2224 A Synthetic Dynamic PVA Photoresin for Ultrafast Volumetric Bioprinting
Qiu, W.; Gehlen, J.; Bernero, M.; Gehre, C.; Schadli, G. N.; Muller, R.; Qin, X.-H.
10.1101/2022.10.20.513079 — bioengineering — Posted on 2022-11-14
2225 Convergent Evolution and B-Cell Recirculation inGerminal Centers in a Human Lymph Node
Pelissier, A.; Stratigopoulou, M.; Donner, N.; Dimitriadis, E.; Bende, R. J.; Guikema, J. E.; Martinez, M. R.; van Noesel, C. J. M.
10.1101/2022.11.09.463832 — evolutionary biology — Posted on 2022-11-14
2226 Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics
Thaler, R.; Yoshizaki, K.; Nguyen, T.; Fukumoto, S.; DenBesten, p.; Bikle, D. D.; Oda, Y.
10.1101/2022.09.08.507153 — developmental biology — Posted on 2022-11-14
2228 Alveolar epithelial cell differentiation during lung repair requires cell-extracellular matrix interactions
Sucre, J. M. S.; Bock, F.; Negretti, N. M.; Benjamin, J. T.; Gulleman, P. M.; Dong, X.; Ferguson, K. T.; Jetter, C. S.; Han, W.; Liu, Y.; Kook, S.; Gokey, J.; Guttentag, S. H.; Kropski, J. A.; Blackwell, T. S.; Zent, R.; Plosa, E. J.
10.1101/2022.08.05.502988 — cell biology — Posted on 2022-11-14
2229 Inhibition drives habituation of a larval zebrafish visual response
Lamire, L.-A.; Haesemeyer, M.; Engert, F.; Granato, M.; Randlett, O.
10.1101/2022.06.17.496451 — neuroscience — Posted on 2022-11-14
2233 Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer
Laise, P.; Turunen, M.; Curiel Garcia, A.; Tomassoni, L.; Maurer, C.; Elyada, E.; Schmierer, B.; Worley, J.; Kesner, J.; Tan, X.; Calvo Fernandez, E.; Wong, K.; Wasko, U.; Tagore, S.; Wang, A. L. E.; Ge, S.; Iuga, A. C.; Griffin, A.; Wong, W.; Manji, G.; Alvarez, M. J.; Notta, F.; Tuveson, D.; Olive, K. P.; Califano, A.
10.1101/2020.10.27.357269 — cancer biology — Posted on 2022-11-14
2234 Bioprinting microporous functional living materials from protein-based core-shell microgels
Ou, Y.; Cao, S.; Zhu, H.; Guo, C.; Zhang, Y.; Yan, W.; Xin, F.; Dong, W.; Zhang, Y.; Narita, M.; Yu, Z.; Knowles, T. P. J.
10.1101/2022.05.03.490444 — bioengineering — Posted on 2022-11-14
2235 Innovation and elaboration on the avian tree of life
Guillerme, T.; Bright, J.; Cooney, C.; Hughes, E. C.; Varley, Z.; Cooper, N.; Beckerman, A. P.; Thomas, G. H.
10.1101/2022.08.12.503188 — evolutionary biology — Posted on 2022-11-14
2236 Terminal differentiation of villus-tip enterocytes is governed by distinct members of Tgfβ superfamily
Berkova, L.; Fazilaty, H.; Yang, Q.; Kubovciak, J.; Stastna, M.; Hrckulak, D.; Vojtechova, M.; Brugger, M. D.; Hausmann, G.; Liberali, P.; Korinek, V.; Basler, K.; Valenta, T.
10.1101/2022.11.11.516138 — cell biology — Posted on 2022-11-14
2240 Metabolic consequences of various fruit-based diets in a generalist insect species
Olazcuaga, L.; Baltenweck, R.; Lemenager, N.; Maia-Grondard, A.; Claudel, P.; Hugueney, P.; Foucaud, J.
10.1101/2022.10.21.513142 — ecology — Posted on 2022-11-14
2241 Autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes.
Fazel Darbandi, S.; An, J. Y.; Lim, K.; Page, N. F.; Liang, L.; Ypsilanti, A.; Markenscoff-Papadimitriou, E.; State, M. W.; Nord, A. S.; Sanders, S. J.; Rubenstein, J. L. R.
10.1101/2022.10.17.512583 — genomics — Posted on 2022-11-14
2242 Selective accumulation of matrix proteins inside of peroxisomal subdomains
Ast, J.; Bäcker, N.; Martorana, D.; Renicke, C.; Stehlik, T.; Heimerl, T.; Taxis, C.; Bange, G.; Bölker, M.; Sandrock, B.; Schink, K.; Freitag, J.
10.1101/2022.10.02.510529 — cell biology — Posted on 2022-11-14
2244 Some like it hotter: differential thermal preferences among lizard color morphs
Thompson, A.; Kapsanaki, V.; Liwanag, H. E. M.; Pafilis, P.; Wang, I. J.; Brock, K. M.
10.1101/2022.11.11.516149 — zoology — Posted on 2022-11-14
2245 Characterizing microplastic ingestion, transformation, and excretion in insects using fluorescent plastics
Ritchie, M. W.; Cheslock, A.; Bourdages, M. P. T.; Hamilton, B. M.; Provencher, J. F.; Allison, J. E.; MacMillan, H. A.
10.1101/2022.11.11.516210 — zoology — Posted on 2022-11-14
2247 Electron Videography of a Lipid-Protein Tango
Smith, J. W.; Carnevale, L. N.; Das, A.; Chen, Q.
10.1101/2022.11.13.516315 — biophysics — Posted on 2022-11-14
2248 Behavioral dissection of hunger states in Drosophila
Weaver, K. J.; Raju, S.; Rucker, R. A.; Chakraborty, T.; Holt, R. A.; Pletcher, S.
10.1101/2022.11.11.516105 — animal behavior and cognition — Posted on 2022-11-14
2249 CHK1-CDC25A-CDK1 regulate cell cycle progression in early mouse embryos to protect genome integrity
Knoblochova, L.; Duricek, T.; Vaskovicova, M.; Zorzompokou, C.; Rayova, D.; Ferencova, I.; Baran, V.; Schultz, R. M.; Hoffmann, E. R.; Drutovic, D.
10.1101/2022.11.13.516318 — developmental biology — Posted on 2022-11-14
2250 Bone Marrow- and Umbilical Cord-Derived Mesenchymal Stem Cell Secretome Alters Gene Expression and Upregulates Motility of Human Endometrial Stromal Cells
Zhao, Q.; Larios, K.; Naaldijk, Y.; Sherman, L.; Chemerinski, A.; Okereke, K.; Rameshwar, P.; Lemenze, A.; Douglas, N. C.; Morelli, S. S.
10.1101/2022.11.12.516251 — cell biology — Posted on 2022-11-14
2252 Effective cell membrane tension is independent of polyacrylamide substrate stiffness
Kreysing, E.; Mc Hugh, J.; Foster, S. K.; Andresen, K.; Greenhalgh, R. D.; Pillai, E. K.; Dimitracopoulos, A.; Keyser, U. F.; Franze, K.
10.1101/2021.11.09.467973 — biophysics — Posted on 2022-11-14
2254 Pulsed stimulated Brillouin microscopy enables high-sensitivity mechanical imaging of live and fragile biological specimens
Yang, F.; Bevilacqua, C.; Hambura, S.; Neves, A.; Gopalan, A.; Watanabe, K.; Govendir, M.; Bernabeu, M.; Ellenberg, J.; Diz-Munoz, A.; Köhler, S.; Rapti, G.; Jechlinger, M.; Prevedel, R.
10.1101/2022.11.10.515835 — bioengineering — Posted on 2022-11-14
2255 Diving Behavior Reveals Humidity Sensing Ability of Water Deprived Planarians
Pei, Y.; Qian, R.; Yan, Y.; Zhang, Y.; Tan, L.; Li, X.; Lu, C.; Chen, Y.; Chi, Y.; Hao, K.; Xu, Z.; Yang, G.; Shao, Z.; Wang, Y.; Huang, K.
10.1101/2022.10.12.511880 — animal behavior and cognition — Posted on 2022-11-14
2256 Genomic innovation and horizontal gene transfer shaped plant colonization and biomass degradation strategies of a globally prevalent fungal pathogen
Sahu, N.; Indic, B.; Wong-Bajracharya, J.; Merenyi, Z.; Ke, H.-M.; Ahrendt, S.; Monk, T.-L.; Kocsube, S.; Drula, E.; Lipzen, A.; Balint, B.; Henrissat, B.; Andreopoulos, B.; Martin, F. M.; Harder, C. B.; Rigling, D.; Ford, K. L.; Foster, G. D.; Pangilinan, J.; Papanicolaou, A.; Barry, K.; LaButti, K.; Viragh, M.; Koriabine, M.; Yan, M.; Riley, R.; Champramary, S.; Plett, K. L.; Grigoriev, I. V.; Tsai, I. J.; Slot, J.; Sipos, G.; Plett, J.; Nagy, L. G.
10.1101/2022.11.10.515791 — genomics — Posted on 2022-11-14
2259 Integration of short- and long-term responses to environmental stimuli shape seasonal transcriptome dynamics
Kurita, Y.; Takimoto, H.; Kamitani, M.; Hashida, Y.; Kashima, M.; Tezuka, A.; Tanabata, T.; Nagano, A. J.
10.1101/2021.08.02.454700 — plant biology — Posted on 2022-11-14
2263 Fendrr synergizes with Wnt signalling to regulate fibrosis related genes during lung development via its RNA:dsDNA Triplex Element
Ali, T.; Rogala, S.; Krause, N. M.; Bains, J. K.; Melissari, M.-T.; Waehrisch, S.; Herrmann, B. G.; Schwalbe, H.; Grote, P.
10.1101/2021.11.02.466973 — developmental biology — Posted on 2022-11-13
2264 Plasmodium DDI1 is a potential therapeutic target and important chromatin-associated protein
Tanneru, N.; Nivya, M. A.; Adhikari, N.; Saxena, K.; Rizvi, Z.; Sudhakar, R.; Nagwani, A. K.; ..., A.; Al-Nihmi, F. M. A.; Arun Kumar, K.; Sijwali, P. S.
10.1101/2021.10.29.466443 — cell biology — Posted on 2022-11-13
2267 Thymic macrophages consist of two populations with distinct localization and origin
Zhou, T.-A.; Hsu, H.-P.; Tu, Y.-H.; Cheng, H.-K.; Lin, C.-Y.; Chen, N.-J.; Tsai, J.-W.; Robey, E. A.; Huang, H.-C.; Hsu, C.-L.; Dzhagalov, I. L.
10.1101/2021.11.04.467238 — immunology — Posted on 2022-11-13
2272 Precision engineering of biological function with large-scale measurements and machine learning
Tack, D. S.; Tonner, P. D.; Pressman, A.; Olson, N. D.; Levy, S. F.; Romantseva, E. F.; Alperovich, N.; Vasilyeva, O.; Ross, D.
10.1101/2022.08.04.502789 — synthetic biology — Posted on 2022-11-13
2273 A Scalable and Adaptive Ultra-high-density Fan-out Strategy for High-throughput Flexible Microelectrodes
Zhang, H.; Wang, Y.; Yang, X.; Yuan, M.; Yang, X.; Gui, Q.; Wang, Y.; Chen, H.; Liu, R.; Pei, W.
10.1101/2022.11.07.515530 — bioengineering — Posted on 2022-11-13
2275 Convergent Evolution and B-Cell Recirculation inGerminal Centers in a Human Lymph Node
Pelissier, A.; Stratigopoulou, M.; Donner, N.; Dimitriadis, E.; Bende, R. J.; Guikema, J. E.; Martinez, M. R.; van Noesel, C. J. M.
10.1101/2022.11.09.463832 — evolutionary biology — Posted on 2022-11-13
2276 Expression bias in retinoic acid responsive genes defines variations in neural differentiation of human pluripotent stem cells
Kim, S. K.; Seo, S.; Stein-O'Brien, G.; Jaishankar, A.; Ogawa, K.; Micali, N.; Luria, V.; Karger, A.; Wang, Y.; Hyde, T.; Kleinman, J.; Voss, T.; Fertig, E.; Shin, J. H.; Burli, R.; Cross, A. J.; Brandon, N. J.; Weinberger, D. R.; Chenoweth, J. G.; Hoeppner, D. J.; Sestan, N.; Colantuoni, C.; McKay, R. D.
10.1101/2021.03.17.435870 — developmental biology — Posted on 2022-11-13
2277 The variegation of human brain vulnerability to rare genetic disorders and convergence with behaviorally defined disorders
Levitis, E.; Liu, S.; Whitman, E. T.; Warling, A.; Torres, E.; Clasen, L. S.; Lalonde, F.; Sarlls, J.; Alexander, D. C.; Raznahan, A.
10.1101/2022.11.12.516252 — neuroscience — Posted on 2022-11-13
2279 Recombinant protein delivery enables modulation of the phototransduction cascade in mouse retina
Asteriti, S.; Marino, V.; Avesani, A.; Biasi, A.; Dal Cortivo, G.; Cangiano, L.; Dell'Orco, D.
10.1101/2022.11.10.516027 — neuroscience — Posted on 2022-11-13
2281 Decoding Motor Plans Using a Closed-Loop Ultrasonic Brain-Machine Interface
Griggs, W. S.; Norman, S. L.; Deffieux, T.; Segura, F.; Osmanski, B.-F.; Chau, G.; Christopoulos, V. N.; Liu, C.; Tanter, M.; Shapiro, M. G.; Andersen, R. A.
10.1101/2022.11.10.515371 — neuroscience — Posted on 2022-11-13
2283 DeepOM: Single-molecule optical genome mapping via deep learning
Nogin, Y.; Detinis Zur, T.; Margalit, S.; Barzilai, I.; Alalouf, O.; Ebenstein, Y.; Shechtman, Y.
10.1101/2022.11.04.512597 — bioinformatics — Posted on 2022-11-13
2285 ExplaiNN: interpretable and transparent neural networks for genomics
Novakovsky, G.; Fornes, O.; Saraswat, M.; Mostafavi, S.; Wasserman, W. W.
10.1101/2022.05.20.492818 — genomics — Posted on 2022-11-13
2288 CelltypeR: A framework to identify and characterize cell types in human midbrain organoids using flow cytometry
Thomas, R. A.; Sirois, J. M.; Li, S.; Gestin, A.; Piscopo, V. E.; Lepine, P.; Mathur, M.; Chen, C. X. Q.; Soubannier, V.; Goldsmith, T. M.; Fawaz, L.; Durcan, T. M.; Fon, E. A.
10.1101/2022.11.11.516066 — neuroscience — Posted on 2022-11-13
2289 SUMO2 Protects Against Tau-induced Synaptic and Cognitive Dysfunction
Orsini, F.; Argyrousi, E. K.; Restelli, E.; Ford, L. K.; Takamura, H.; Matsuzaki, S.; Zentilin, L.; Pascente, R.; Kanaan, N. M.; Soni, R.; Katayama, T.; Chiesa, R.; Forloni, G.; Kosik, K. S.; Kandel, E. R.; Fraser, P. E.; Arancio, O.; Fioriti, L.
10.1101/2022.11.11.516192 — neuroscience — Posted on 2022-11-13
2293 Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease
Leyns, C. E. G.; Prigent, A.; Beezhold, B.; Yao, L.; Hatcher, N.; Tao, P.; Kang, J.; Suh, E.; Van Deerlin, V. M.; Trojanowski, J. Q.; Lee, V. M. Y.; Kennedy, M.; Fell, M.; Henderson, M. X.
10.1101/2022.11.11.516171 — neuroscience — Posted on 2022-11-13
2295 Monkey-to-human transfer of brain computer interface decoders
Rizzoglio, F.; Altan, E.; Ma, X.; Bodkin, K. L.; Dekleva, B.; Solla, S. A.; Kennedy, A.; Miller, L. E.
10.1101/2022.11.12.515040 — neuroscience — Posted on 2022-11-13
2302 Pilot MRI study of carbon monoxide (CO) against ischemic stroke in mice: blood brain barrier integrity and metabolic pattern
Oliveira, S. R.; Castelhano, J.; Sereno, J.; Petrella, L.; Castelo-Branco, M.; Vieira, H. L.; Duarte, C. B.
10.1101/2022.11.10.515956 — neuroscience — Posted on 2022-11-13
2305 Brain-wide representations of behavior spanning multiple timescales and states in C. elegans
Atanas, A. A.; Kim, J.; Wang, Z.; Bueno, E.; Becker, M.; Kang, D.; Park, J.; Estrem, C.; Kramer, T. S.; Baskoylu, S.; Mansingkha, V.; Flavell, S. W.
10.1101/2022.11.11.516186 — neuroscience — Posted on 2022-11-13
2309 Quantifying Evoked Responses through Encoded Information
Fuhrer, J.; Glette, K.; Endestad, T.; Solbakk, A.-K.; Blenkmann, A.
10.1101/2022.11.11.516096 — neuroscience — Posted on 2022-11-13
2314 Transforming a head direction signal into a goal-oriented steering command
Westeinde, E. A.; Kellogg, E.; Dawson, P. M.; Lu, J.; Hamburg, L.; Midler, B.; Druckmann, S.; Wilson, R. I.
10.1101/2022.11.10.516039 — neuroscience — Posted on 2022-11-13
2318 3MDR, a microcomputer-controlled visual stimulation device for psychotherapy-like treatments of mice
Jauch, I.; Kamm, J.; Benn, L.; Rettig, L.; Friederich, H.-C.; Tesarz, J.; Kuner, T.; Wieland, S.
10.1101/2022.11.10.516035 — neuroscience — Posted on 2022-11-13
2319 Neuroelectrophysiology-Compatible Electrolytic Lesioning
Bray, I. E.; Clarke, S. E.; Casey, K. M.; Nuyujukian, P.; Brain Interfacing Laboratory,
10.1101/2022.11.10.516056 — neuroscience — Posted on 2022-11-13
2322 Optopharmacological tools for precise spatiotemporal control of oxytocin signaling in the central nervous system and periphery
Ahmed, I.; Liu, J.; Gieniec, K.; Bair-Marshall, C.; Adewakun, A.; Hetzler, B.; Arp, C.; Khatri, L.; Vanwalleghem, G.; Seidenberg, A.; Cowin, P.; Trauner, D.; Chao, M.; Davis, F.; Tsien, R.; Froemke, R.
10.1101/2022.11.10.516001 — neuroscience — Posted on 2022-11-13
2324 Brain-wide measurement of protein turnover with high spatial and temporal resolution
Mohar, B.; Grimm, J. B.; Patel, R.; Brown, T. A.; Tillberg, P.; Lavis, L. D.; Spruston, N.; Svoboda, K.
10.1101/2022.11.12.516226 — neuroscience — Posted on 2022-11-13
2327 Neuromodulatory organization in the developing rat somatosensory cortex
Colangelo, C.; Munoz, A.; Antonietti, A.; Anton-Fernandez, A.; Romani, A.; Herttuainen, J.; Markram, H.; DeFelipe, J.; Ramaswamy, S.
10.1101/2022.11.11.516108 — neuroscience — Posted on 2022-11-13
2330 Metal-Induced Energy Transfer (MIET) for Live-Cell Imaging with Fluorescent Proteins
Hauke, L.; Isbaner, S.; Ghosh, A.; Guido, I.; Turco, L.; Chizhik, A. I.; Gregor, I.; Karedla, N.; Rehfeldt, F.; Enderlein, J.
10.1101/2022.11.12.516247 — biophysics — Posted on 2022-11-13
2333 Systematic characterization of brain cellular crosstalk signaling networks in Alzheimer's disease reveals a novel role for SEMA6D in TREM2-dependent microglial activation
D'Oliveira Albanus, R.; Finan, G.; Brase, L.; Chen, S.; Guo, Q.; Kannan, A.; Acquarone, M.; You, S.-F.; Novotny, B. C.; Ribeiro Pereira, P. M.; Morris, J. C.; Bateman, R. J.; McDade, E.; Cruchaga, C.; Chhatwal, J. P.; Dominantly Inherited Alzheimer Network (DIAN), ; Mace, E. E.; Benitez, B. A.; Piccio, L.; Sutherland, G. T.; Ma, Q.; Fu, H.; Karch, C. M.; Harari, O.; Kim, T.-W.
10.1101/2022.11.11.516215 — neuroscience — Posted on 2022-11-13
2334 Neuropathic injury drives a generalized negative affective state in mice
Norris, M. R.; Bilbily, J.; Becker, L. J.; Borges, G.; Chang, Y.-H.; Dunn, S. S.; Madasu, M. K.; Al-Hasani, R.; Creed, M. C.; McCall, J. G.
10.1101/2022.11.10.515959 — neuroscience — Posted on 2022-11-13
2336 More hot air: measuring the paradox of European ecology conferences
Smith, G. C.; Begeman, L.; Coles, A.; Gilot-Fromont, E.; Lopez-Olvera, J. R.; Vale, A.; Vogler, B. R.; Kuiken, T.
10.1101/2022.11.10.516028 — scientific communication and education — Posted on 2022-11-13
2337 Genomic variations drive phenotypic heterogeneity in pancreatic cancer cells
Xie, G.; Usman, O. H.; Kumar, S.; Patel, D.; Kavanaugh, M.; Wang, Y. J.; Irianto, J.
10.1101/2022.11.11.516211 — cancer biology — Posted on 2022-11-13
2338 Differential roles of extracellular matrix proteins on primary and metastatic pancreatic cancer cells
Usman, O. H.; Kumar, S.; Walker, R. R.; Xie, G.; Jalil, A. R.; Ramakrishnan, S.; Dooling, L. J.; Wang, Y. J.; Irianto, J.
10.1101/2022.11.11.516201 — cancer biology — Posted on 2022-11-13
2341 The impact of culture variables on 3D human in vitro bone remodeling; a design of experiments approach
de Wildt, B. W. M.; Cuypers, L. A. B.; Cramer, E. . E. A.; Wentzel, A. S.; Ito, K.; Hofmann, S.
10.1101/2022.11.11.516134 — bioengineering — Posted on 2022-11-13
2346 Enhanced protein synthesis is a defining requirement for neonatal B cell development
Akerstrand, H.; Boldrin, E.; Montano, G.; Vanhee, S.; Olsson, K.; Krausse, N.; Vergani, S.; Ciesla, M.; Bellodi, C.; Yuan, J.
10.1101/2022.11.11.515795 — immunology — Posted on 2022-11-13
2347 Mutation-Guided Vaccine Design: A Strategy for Developing Boosting Immunogens for HIV Broadly Neutralizing Antibody Induction
Wiehe, K.; Saunders, K. O.; Stalls, V.; Cain, D. W.; Venkatayogi, S.; Martin Beem, J. S.; Berry, M.; Evangelous, T.; Henderson, R.; Hora, B.; Xia, S.-M.; Jiang, C.; Newman, A.; Bowman, C.; Lu, X.; Bryan, M. E.; Bal, J.; Sanzone, A.; Chen, H.; Eaton, A.; Tomai, M. A.; Fox, C. B.; Tam, Y.; Barbosa, C.; Bonsignori, M.; Muramatsu, H.; Alam, M.; Montefiori, D.; Williams, W. B.; Pardi, N.; Tian, M.; Weissman, D.; Alt, F. W.; Acharya, P.; Haynes, B. F.
10.1101/2022.11.11.516143 — immunology — Posted on 2022-11-13
2348 Natural Killer activating Multimeric Immunotherapeutic compleXes (NaMiX) induce cytotoxic activity and killing of HIV-1 infected cells
Schober, R.; Brandus, B.; Laeremans, T.; Iserentant, G.; Dessilly, G.; Zimmer, J.; Moutschen, M.; Aerts, J. L.; Dervillez, X.; Seguin-Devaux, C.
10.1101/2022.11.11.516216 — immunology — Posted on 2022-11-13
2352 Catch bonds in sickle cell disease: shear-enhanced adhesion of red blood cells to laminin
Goreke, U.; Iram, S.; Singh, G.; Dominguez-Medina, S.; Man, Y.; Bode, A.; An, R.; Little, J. A.; Wirth, C. L.; Hinczewski, M.; Gurkan, U. A.
10.1101/2022.11.12.515898 — biophysics — Posted on 2022-11-13
2353 Degenerative changes are associated with severity of anterior cruciate ligament injury within the skeletally immature joint
Howe, D.; Thompson, J. D.; Teeter, S. D.; Barlow, O.; Griffith, E. H.; Schnabel, L. V.; Spang, J. T.; Fisher, M. B.
10.1101/2022.11.12.516262 — bioengineering — Posted on 2022-11-13
2355 X-inactivation states of single cell transcriptomes reveal cellular phylogenies in human females
Predeus, A.; Arutyunyan, A.; Jardine, L.; Suo, C.; Dann, E.; Hoo, R.; Prete, M.; Haniffa, M.; Mitchell, T. J.; Vento-Tormo, R.; Young, M. D.
10.1101/2022.11.10.515645 — genomics — Posted on 2022-11-13
2356 Single-cell gene expression and chromatin accessibility profiling of human pancreatic islets at basal and stimulatory conditions nominates mechanisms of type 1 diabetes genetic risk
D'Oliveira Albanus, R.; Tang, X.; Taylor, H. J.; Erdos, M.; Narisu, N.; Han, Y.; Orchard, P.; Varshney, A.; Liu, C.; Naji, A.; HPAP Consortium, ; Collins, F. S.; Chen, S.; Parker, S. C. J.
10.1101/2022.11.12.516291 — genomics — Posted on 2022-11-13
2362 A physiologically based model of bile acid metabolism in mice
Kister, B.; Viehof, A.; Rolle-Kampczyk, U.; Schwentker, A.; Treichel, N. S.; Jennings, S.; Wirtz, T.; Blank, L. M.; Hornef, M. W.; von Bergen, M.; Clavel, T.; Kuepfer, L.
10.1101/2022.11.10.515857 — systems biology — Posted on 2022-11-13
2366 DeepCCI: a deep learning framework for identifying cell-cell interactions from single-cell RNA sequencing data
Jiang, Q.; Yang, W.; Xu, Z.; Luo, M.; Cai, Y.; Xu, C.; Wang, P.; Wei, S.; Xue, G.; Jing, X.; Cheng, R.; Que, J.; Zhou, W.; Pang, F.; Nie, H.
10.1101/2022.11.11.516061 — bioinformatics — Posted on 2022-11-13
2367 Genomic innovation and horizontal gene transfer shaped plant colonization and biomass degradation strategies of a globally prevalent fungal pathogen
Sahu, N.; Indjic, B.; Wong-Bajracharya, J.; Merenyi, Z.; Ke, H.-M.; Ahrendt, S.; Monk, T.-L.; Kocsube, S.; Drula, E.; Lipzen, A.; Balint, B.; Henrissat, B.; Andreopoulos, B.; Martin, F. M.; Harder, C. B.; Rigling, D.; Ford, K. L.; Foster, G. D.; Pangilinan, J.; Papanicolaou, A.; Barry, K.; LaButti, K.; Viragh, M.; Koriabine, M.; Yan, M.; Riley, R.; Champramary, S.; Plett, K. L.; Grigoriev, I. V.; Tsai, I. J.; Slot, J.; Sipos, G.; Plett, J.; Nagy, L. G.
10.1101/2022.11.10.515791 — genomics — Posted on 2022-11-13
2369 Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma-derived metabolite cues
Kyle, K. E.; Puckett, S. P.; Caraballo Rodriguez, A. M.; Rivera Chavez, J.; Samples, R. M.; Earp, C. E.; Raja, H. A.; Pearce, C. J.; Ernst, M.; van der Hooft, J. J. J.; Adams, M. E.; Oberlies, N. H.; Dorrestein, P. C.; Klassen, J. L.; Balunas, M. J.
10.1101/2022.11.12.516288 — microbiology — Posted on 2022-11-13
2370 Plethora of QTLs found in Arabidopsis thaliana reveals complexity of genetic variation for photosynthesis in dynamic light conditions
Theeuwen, T. P. J. M.; Logie, L. L.; Put, S.; Bagheri, H.; Losinski, K.; Drouault, J.; Flood, P. J.; Hanhart, C.; Becker, F. F. M.; Wijfjes, R.; Hall, D.; Kramer, D. M.; Harbinson, J.; Aarts, M. G. M.
10.1101/2022.11.13.516256 — plant biology — Posted on 2022-11-13
2371 Contrasting effector profiles between bacterial colonisers of kiwifruit reveal redundant roles and interplay converging on PTI-suppression and RIN4
Jayaraman, J.; Yoon, M.; Hemara, L. M.; Bohne, D.; Tahir, J.; Chen, R.; Brendolise, C.; Rikkerink, E. H.; Templeton, M. D.
10.1101/2022.11.12.516272 — plant biology — Posted on 2022-11-13
2372 Plastid DNA sequences and oospore characters of some European species of Tolypella section Tolypella (Obtusifolia, Characeae) indicate a new cryptic Tolypella species from the Mediterranean island Sardinia
Holzhausen, A.; Nowak, P.; Ballot, A.; Becker, R.; Gebert, J.; Gregor, T.; Karol, K. G.; Lambert, E.; Perez, W.; Raabe, U.; Schneider, S. C.; Stewart, N.; van de Weyer, K.; Wilde, V.; Schubert, H.
10.1101/2022.11.11.516156 — plant biology — Posted on 2022-11-13
2374 The NDH complex reveals a trade-off that constrains maximising photosynthesis in Arabidopsis thaliana
Theeuwen, T. P. J. M.; Lawson, A. W.; Tijink, D.; Fornaguera, F.; Becker, F. F. M.; Caracciolo, L.; Fisher, N.; Kramer, D. M.; Wijnker, E.; Harbinson, J.; Aarts, M. G. M.
10.1101/2022.11.13.516254 — plant biology — Posted on 2022-11-13
2375 MSP1 encodes an essential RNA-binding PPR factor required for nad1 maturation and complex I biogenesis in Arabidopsis mitochondria
Best, C.; Mizrahi, R.; Edris, R.; Tang, H.; Zer, H.; Colas des Francs-Small, C.; Finkel, O. M.; Zhu, H.; Small, I. D.; Ostersetzer, O.
10.1101/2022.11.12.516219 — plant biology — Posted on 2022-11-13
2376 Latch Verified Bulk-RNA Seq toolkit: a cloud-based suite of workflows for bulk RNA-seq quality control, analysis, and functional enrichment
Le, H. G. B. H.; Steenwyk, J. L.; Manske, N.; Smolin, M.; Abdulali, A.; Kamat, A.; Kanchana, R.; Giffin, K.; Andere, A.; Workman, K.
10.1101/2022.11.10.516016 — bioinformatics — Posted on 2022-11-13
2378 The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling
Matos-Filipe, P.; Garcia-Illarramendi, J. M.; Jorba, G.; Oliva, B.; Farres, J.; Mas, J. M.
10.1101/2022.11.10.515995 — bioinformatics — Posted on 2022-11-13
2380 Structural basis for ubiquitylation by HOIL-1
Wu, Q.; Koliopoulos, M. G.; Rittinger, K.; Stieglitz, B.
10.1101/2022.11.13.516300 — biochemistry — Posted on 2022-11-13
2384 Neonatal Fc receptor is a functional receptor for human astrovirus
Haga, K.; Takai-Todaka, R.; Kato, A.; Nakanishi, A.; Katayama, K.
10.1101/2022.11.13.516297 — microbiology — Posted on 2022-11-13
2385 Flap-enabled next-generation capture (FENGC): precision targeted single-molecule profiling of epigenetic heterogeneity, chromatin dynamics, and genetic variation
Zhou, M.; Nabilsi, N. H.; Wang, A.; Gauthier, M.-P. L.; Murray, K. O.; Azari, H.; Owens, W. S.; Newman, J. R. B.; Pardo-Palacios, F. J.; Conesa, A.; Riva, A.; Clanton, T. L.; Reynolds, B. A.; Concannon, P.; Brant, J. O.; Bacher, R.; Kladde, M. P.
10.1101/2022.11.08.515732 — cancer biology — Posted on 2022-11-13
2392 Time-resolved cryo-EM reveals early ribosome assembly in action
Qin, B.; Lauer, S. M.; Balke, A.; Vieira-Vieira, C.; Buerger, J.; Mielke, T.; Selbach, M.; Scheerer, P.; Spahn, C.; Nikolay, R.
10.1101/2022.11.12.516267 — biophysics — Posted on 2022-11-12
2393 Glycerolipid defects in skeletal muscle contribute to rhabdomyolysis in Tango2 deficiency
Casey, J. G.; Kim, E. S.; Tao, B. S.; Mansur, A.; Wallace, E. D.; Gupta, V. A.
10.1101/2022.11.12.516274 — genetics — Posted on 2022-11-12
2394 West Nile Virus spread in Europe - phylogeographic pattern analysis and key drivers
Lu, L.; Zhang, F.; Oude Munnink, B.; Munger, E.; Sikkema, R.; Pappa, S.; Tsioka, K.; Sinigaglia, A.; Molin, E. D.; Shih, B.; Gunther, A.; Pohlmann, A.; Beer, M.; Taylor, R. A.; Bartumeus, F. A.; Woolhouse, M. E. J.; Aarestrup, F. M.; Barzon, L.; Papa, A.; Lycett, S. J.; Koopmans, M.
10.1101/2022.11.10.515886 — evolutionary biology — Posted on 2022-11-12
2396 Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration
Ng, B.; Huang, K. Y.; Pua, C. J.; Lim, W.-W.; Kuthubudeen, F.; Hii, A. A.; Viswanathan, S.; Petretto, E. G.; Cook, S. A.
10.1101/2022.11.11.516109 — immunology — Posted on 2022-11-12
2399 Elimusertib outperforms standard of care chemotherapy in preclinical patient-derived pediatric solid tumor models
Pusch, F. F.; Dorado Garcia, H.; Xu, R.; Gürgen, D.; Bei, Y.; Brückner, L.; Röefzaad, C.; von Stebut, J.; Bardinet, V.; Chamorro Gonzalez, M. d. R.; Eggert, A.; Schulte, J. H.; Hundsdörfer, P.; Seifert, G.; Haase, K.; Schäfer, B.; Wachtel, M.; Kühl, A.; Ortiz, M.; Wengner, A. M.; Scheer, M.; Henssen, A. G.
10.1101/2022.11.10.515290 — cancer biology — Posted on 2022-11-12
2400 RUNX1 is regulated by androgen receptor to promote cancer stem markers and chemotherapy resistance in triple negative breast cancer.
Fernandez, N. B.; Sosa, S. M.; Roberts, J. T.; Recouvreux, M. S.; Rocha-Viegas, L.; Christenson, J. L.; Spoelstra, N. S.; Couto, F. L.; Raimondi, A. R.; Richer, J. K.; Rubinstein, N.
10.1101/2022.11.12.516193 — cancer biology — Posted on 2022-11-12
2402 Mapping phosphorylation post-translational modifications along single peptides with nanopores
Nova, I. C.; Ritmejeris, J.; Brinkerhoff, H.; Koenig, T. J. R.; Gundlach, J. H.; Dekker, C.
10.1101/2022.11.11.516163 — biophysics — Posted on 2022-11-12
2404 A DNA origami fiducial for accurate 3D AFM imaging
Kolbeck, P. J.; Dass, M.; Martynenko, I.; van Dijk-Moes, R.; Brouwer, K. J. H.; van Blaaderen, A.; Vanderlinden, W.; Liedl, T.; Lipfert, J.
10.1101/2022.11.11.516090 — biophysics — Posted on 2022-11-12
2406 Two pup vocalization types are genetically and functionally separable in deer mice
Jourjine, N.; Woolfolk, M. L.; Sanguinetti-Scheck, J. I.; Sabatini, J. E.; McFadden, S.; Lindholm, A. K.; Hoekstra, H. E.
10.1101/2022.11.11.516230 — evolutionary biology — Posted on 2022-11-12
2408 Hotspots for snake fungal disease across Europe are maintained by host and pathogen identity
Blanvillain, G.; Lorch, J.; Joudrier, N.; Bury, S.; Cuenot, T.; Franzen, M.; Freiria, F. M.; Guiller, G.; Halpern, B.; Kolanek, A.; Kurek, K.; Lourdais, O.; Michon, A.; Musilova, R.; Schweiger, S.; Szulc, B.; Ursenbacher, S.; Zinenko, O.; Hoyt, J. R.
10.1101/2022.11.10.515990 — ecology — Posted on 2022-11-12
2409 Small proteome of the nitrogen-fixing plant symbiont Sinorhizobium meliloti
Hadjeras, L.; Heiniger, B.; Maass, S.; Scheuer, R.; Gelhausen, R.; Azarderakhsh, S.; Barth-Weber, S.; Backofen, R.; Becher, D.; Ahrens, C. H.; Sharma, C. M.; Evguenieva-Hackenberg, E.
10.1101/2022.11.12.516264 — molecular biology — Posted on 2022-11-12
2414 Genome-scale CRISPR screening reveals host factors required for ribosome formation and viral replication
Ohlson, M. B.; Kumar, A.; Eitson, J. L.; Jang, S.; Ni, C.; Xing, C.; Buszczak, M.; Schoggins, J. W.
10.1101/2022.11.12.515717 — microbiology — Posted on 2022-11-12
2415 Risk Assessment of the newly emerged H7N9 avian influenza viruses
Chang, P.; Sadeyen, J.-R.; Bhat, S.; Daines, R.; Hussain, A.; Yilmaz, H.; Iqbal, M.
10.1101/2022.11.11.516200 — microbiology — Posted on 2022-11-12
2416 PD-1 is induced on tumor-associated macrophages in obesity to directly restrain anti-tumor immunity
Bader, J. E.; Wolf, M. M.; Madden, M. Z.; Reinfeld, B. I.; Arner, E. N.; Hathaway, E. S.; Steiner, K. K.; Needle, G. A.; Landis, M. D.; Cottam, M. A.; Ye, X.; Christofides, A.; Boussiotis, V. A.; Haake, S. M.; Beckermann, K. E.; Rathmell, W. K.; Hasty, A. H.; Rathmell, J. C.
10.1101/2022.11.12.515348 — immunology — Posted on 2022-11-12
2421 ASO targeting temperature-controlled RBM3 poison exon splicing prevents neurodegeneration in vivo
Preussner, M.; Smith, H. L.; Zhang, M.; Hughes, D.; Emmerichs, A.-K.; Scalzitti, S.; Peretti, D.; Swinden, D.; Neumann, A.; Haltenhof, T.; Mallucci, G. R.; Heyd, F.
10.1101/2022.10.26.513170 — molecular biology — Posted on 2022-11-12
2428 Decoding murine cytomegalovirus
Lodha, M.; Muchsin, I.; Jürges, C.; Juranic Lisnic, V.; L'Hernault, A.; Rutkowski, A.; Prusty, B.; Grothey, A.; Milic, A.; Hennig, T.; Jonjic, S.; Friedel, C.; Erhard, F.; Doelken, L.
10.1101/2022.11.10.515907 — microbiology — Posted on 2022-11-12
2429 Terminal differentiation of enterocytes is governed by distinct members of Tgfβ superfamily
Valenta, T.; Berkova, L.; Fazilaty, H.; Yang, Q.; Kubovciak, J.; Stastna, M.; Hrckulak, D.; Vojtechova, M.; Brugger, M.; Hausmann, G.; Liberali, P.; Korinek, V.; Basler, K.
10.1101/2022.11.11.516138 — cell biology — Posted on 2022-11-12
2430 Parallel Activation of Src and Hif1α Increases Localized Glycolytic ATP Generation for Re-assembly of Endothelial Adherens Junctions
Wang, L.; Gajwani, P.; Chaturvedi, P.; Hong, Z.; Ye, Z.; Schwarz, G.; Pohl-Avila, N.; Ray, A.-M.; Krantz, S.; Toth, P. T.; Leckband, D. E.; Karginov, A. V.; Rehman, J.
10.1101/2022.11.11.516184 — cell biology — Posted on 2022-11-12
2432 A miRNA screen identifies a transcriptional program controlling adult stem cell maintenance in mammary organoids
Delom, F.; Vlachavas, E.-I.; Lemaitre, G.; Robert, J.; Chatziioannou, A.; Puceat, M.; Fessart, D.
10.1101/314658 — cell biology — Posted on 2022-11-12
2435 NORDIC Increases the Sensitivity and Preserves the Spatiotemporal Precision of fMRI Responses
Dowdle, L. T.; Vizioli, L.; Moeller, S.; Akcakaya, M.; Olman, C.; Ghose, G. M.; Yacoub, E.; Ugurbil, K.
10.1101/2021.08.26.457833 — neuroscience — Posted on 2022-11-12
2436 Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages
Causeret, F.; Fayon, M.; Moreau, M. X.; Ne, E.; Oleari, R.; Parras, C.; Cariboni, A.; Pierani, A.
10.1101/2022.11.12.514524 — developmental biology — Posted on 2022-11-12
2437 A tracheal aspirate-derived airway basal cell model reveals a pro-inflammatory epithelial defect in congenital diaphragmatic hernia
Wagner, R.; Amonkar, G. M.; Wang, W.; Shui, J. E.; Bankoti, K.; Tse, W. H.; High, F. A.; Zalieckas, J.; Buchmiller, T. L.; Zani, A.; Keijzer, R.; Donahoe, P. K.; Lerou, P. H.; Ai, X.
10.1101/2022.11.10.515365 — developmental biology — Posted on 2022-11-12
2441 Male mammalian meiosis and spermiogenesis is critically dependent on the shared functions of the katanins KATNA1 and KATNAL1
Dunleavy, J. E.; Graffeo, M.; Wozniak, K.; O'Connor, A. E.; Merriner, D. J.; Nguyen, J.; Schittenhelm, R. B.; Houston, B. J.; O'Bryan, M.
10.1101/2022.11.11.516072 — cell biology — Posted on 2022-11-12
2443 FAP106 is an interaction hub required for stable assembly of conserved and lineage-specific proteins at the cilium inner junction
Shimogawa, M. M.; Wijono, A. S.; Wang, H.; Sha, J.; Szombathy, N.; Vadakkan, S.; Pelayo, P.; Jonnalagadda, K.; Wohlschlegel, J. A.; Zhou, Z. H.; Hill, K.
10.1101/2022.11.11.516029 — cell biology — Posted on 2022-11-12
2444 The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus
Bhosle, V. K.; Sun, C.; Patel, S.; Westman, J.; Ammendolia, D. A.; Fine, N.; Li, Z.; Sharma, M.; Glogauer, J.; Capurro, M. I.; Jones, N. L.; Glogauer, M.; Grinstein, S.; Robinson, L. A.
10.1101/2022.11.11.515814 — cell biology — Posted on 2022-11-12
2445 IL-11 disrupts alveolar epithelial progenitor function
Kortekaas, R. K.; Geillinger-Kaestle, K. E.; Borghuis, T.; Belharch, K.; Webster, M.; Timens, W.; Burgess, J. K.; Gosens, R.
10.1101/2022.11.11.516088 — cell biology — Posted on 2022-11-12
2447 Germinal Centers Convergent Evolution and B cell Recirculation in Human Lymph Nodes
Pelissier, A.; Stratigopoulou, M.; Donner, N.; Dimitriadis, E.; Bende, R. J.; Guikema, J. E.; Martinez, M. R.; van Noesel, C. J. M.
10.1101/2022.11.09.463832 — evolutionary biology — Posted on 2022-11-12
2449 Neurochemistry-enriched dynamic causal models of magnetoencephalography, using magnetic resonance spectroscopy
Jafarian, A.; Hughes, L.; Adams, N. E.; Lanskey, J.; Naessens, M.; Rouse, M. A.; Murley, A. G.; Friston, K.; Rowe, J.
10.1101/2022.06.17.493881 — neuroscience — Posted on 2022-11-12
2450 Identifying Optimal Neuroinflammation Treatment Using Nanoligomer Discovery Engine
Sharma, S.; Borski, C.; Hanson, J.; Garcia, M. A.; Link, C. D.; Hoeffer, C. A.; Chatterjee, A.; Nagpal, P.
10.1101/2022.08.23.505002 — neuroscience — Posted on 2022-11-12
2451 Catch bond models may explain how force amplifies TCR signaling and antigen discrimination
Choi, H.-K.; Li, K.; Cong, P.; Rushdi, M. N.; Ge, C.; Chen, W.; Lou, J.; Zhu, C.
10.1101/2022.01.17.476694 — biophysics — Posted on 2022-11-12
2453 A bi-functional PARP-HDAC inhibitor with activity in Ewing sarcoma
Ramos, L.; Truong, S.; Zhai, B.; Joshi, J.; Ghaidi, F.; Lizardo, M. M.; Shyp, T.; Adomat, H.; LeBihan, S.; Collins, C. C.; Bacha, J.; Brown, D.; Langlands, J.; Shen, W.; Lallous, N.; Sorensen, P. H.; Daugaard, M.
10.1101/2022.11.10.515994 — cancer biology — Posted on 2022-11-12
2454 A compendium of genetic regulatory effects across pig tissues
Jinyan, T.; Gao, Y.; Yin, H.; Bai, Z.; Liu, S.; Zeng, H.; Bai, L.; Cai, Z.; Zhao, B.; Li, X.; Xu, Z.; Lin, Q.; Pan, Z.; Yang, W.; Yu, X.; Guan, D.; Hou, Y.; Keel, B. N.; Rohrer, G. A.; Lindholm-Perry, A. K.; Oliver, W. T.; Ballester, M.; Crespo-Piazuelo, D.; Quintanilla, R.; Canela-Xandri, O.; Rawlik, K.; Xia, C.; Yao, Y.; Zhao, Q.; Yao, W.; Yang, L.; Li, H.; Zhang, H.; Liao, W.; Chen, T.; Karlskov-Mortensen, P.; Fredholm, M.; Amills, M.; Clop, A.; Giuffra, E.; Wu, J.; Cai, X.; Diao, S.; Pan, X.; Wei, C.; Li, J.; Cheng, H.; Wang, S.; Su, G.; Sahana, G.; Lund, M. S.; Dekkers, J. C. M.; Kramer,
10.1101/2022.11.11.516073 — genomics — Posted on 2022-11-11
2457 Nucleus accumbens dopamine release reflects the selective nature of pair bonds
Pierce, A. F.; Protter, D. S.; Chapel, G. D.; Cameron, R. T.; Donaldson, Z.
10.1101/2022.11.10.516053 — neuroscience — Posted on 2022-11-11
2459 Auditory cortex encodes lipreading information through spatially distributed activity
Karthik, G.; Cao, C. Z.; Demidenko, M. I.; Jahn, A.; Stacey, W.; Wasade, V. S.; Brang, D.
10.1101/2022.11.11.516209 — neuroscience — Posted on 2022-11-11
2461 Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells
Glaser, V.; Flugel, C. L.; Kath, J.; Du, W.; Drosdek, V.; Franke, C.; Stein, M.; Pruss, A.; Schmueck-Henneresse, M.; Volk, H.-D.; Reinke, P.; Wagner, D. L.
10.1101/2022.11.11.516008 — bioengineering — Posted on 2022-11-11
2462 Structural Assessment of the Full-Length Wild-Type Tumor Suppressor Protein p53 by Mass Spectrometry-Guided Computational Modeling
Di Ianni, A.; Tueting, C.; Kipping, M.; Ihling, C. H.; Koeppen, J. S.; Iacobucci, C.; Arlt, C.; Kastritis, P. L.; Sinz, A.
10.1101/2022.11.11.516092 — biochemistry — Posted on 2022-11-11
2464 Pentameric assembly of glycine receptor intracellular domains provides insights into gephyrin clustering
Macha, A.; Gruenewald, N.; Havarushka, N.; Burdina, N.; Toelzer, C.; Merkler, Y.; Cabrera-Orefice, A.; Pauly, T.; Brandt, U.; Nagel-Steger, L.; Niefind, K.; Schwarz, G.
10.1101/2022.11.10.512828 — biochemistry — Posted on 2022-11-11
2465 Tautomer-specific deacylation and {Omega}-loop flexibility explain carbapenem-hydrolyzing, broad-spectrum activity of the KPC-2 β-lactamase
Tooke, C. L.; Hinchliffe, P.; Beer, M.; Zinovjev, K.; Colenso, C. K.; Schofield, C. J.; Mulholland, A. J.; Spencer, J.
10.1101/2022.11.11.516172 — biochemistry — Posted on 2022-11-11
2466 Pyrophosphoproteomics: extensive protein pyrophosphorylation revealed in human cell lines
Morgan, J. A. M.; Singh, A.; Kurz, L.; Nadler-Holly, M.; Penkert, M.; Krause, E.; Liu, F.; Bhandari, R.; Fiedler, D.
10.1101/2022.11.11.516170 — biochemistry — Posted on 2022-11-11
2467 Environmental activity-based protein profiling for function-driven enzyme discovery from natural communities
Ninck, S.; Klaus, T.; Kochetkova, T. V.; Esser, S. P.; Sewald, L.; Kaschani, F.; Braesen, C.; Probst, A. J.; Kublanov, I.; Siebers, B.; Kaiser, M.
10.1101/2022.11.11.516116 — biochemistry — Posted on 2022-11-11
2471 Inflammation-Responsive Micellar Nanoparticles from Degradable Polyphosphoramidates for Targeted Delivery to Myocardial Infarction
Liang, Y.; Sullivan, H.; Carrow, K.; Korpanty, J.; Worthington, K.; Luo, C.; Christman, K. L.; Gianneschi, N. C.
10.1101/2022.11.11.516224 — biochemistry — Posted on 2022-11-11
2473 Core Defense Hotspots within Pseudomonas aeruginosa are a consistent and rich source of anti-phage defense systems
Johnson, M. C.; Laderman, E.; Huiting, E. C.; Zhang, C.; Davidson, A. R.; Bondy-Denomy, J. R.
10.1101/2022.11.11.516204 — genomics — Posted on 2022-11-11
2476 The circular RNA Ataxia-telangiectasia mutated (cATM) regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms
Fasolo, F.; Winsky, G.; Li, Z.; Wu, Z.; Winter, H.; Glukha, N.; Roy, J.; Hultgren, R.; Pauli, J.; Busch, A.; Sachs, N.; Knappich, C.; Eckstein, H.-H.; Boon, R.; Paloschi, V.; Maegdefessel, L.
10.1101/2022.11.11.516115 — molecular biology — Posted on 2022-11-11
2477 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless
Jagtap, P. K. A.; Mueller, M.; Kiss, A. E.; Thomae, A. W.; Lapouge, K.; Beck, M.; Becker, P. B.; Hennig, J.
10.1101/2022.11.11.516098 — molecular biology — Posted on 2022-11-11
2478 Defining transcription factor nucleosome binding with Pioneer-seq
Tsompana, M.; Wilson, P.; Murugaiyan, V.; Handelmann, C.; Buck, M. J.
10.1101/2022.11.11.516133 — molecular biology — Posted on 2022-11-11
2479 ame-miR-34 modulates the larval body weight and immune response of Apis mellifera workers to Ascosphara apis invasion
wu, y.; Guo, Y.; Fan, X.; Zhao, H.; Zhang, Y.; Guo, S.; Jing, X.; Liu, Z.; Feng, P.; Liu, X.; Zou, P.; Li, Q.; Na, Z.; Zhang, K.; Chen, D.; Guo, R.
10.1101/2022.11.10.515915 — molecular biology — Posted on 2022-11-11
2480 Transcription-independent hold of the G1/S transition is exploited to cope with DNA replication stress
Jin, Y.; lan, G.; Zhang, J.; Sun, H.; Li, X.; Cao, Q.; Tang, C.; Yang, X.; Lou, H.; Hou, W.
10.1101/2022.11.10.515958 — molecular biology — Posted on 2022-11-11
2484 Fluid flow structures gut microbiota biofilm communities by distributing public goods
Wong, J. P. H.; Fischer-Stettler, M.; Zeeman, S. C.; Battin, T. J.; Persat, A.
10.1101/2022.11.11.516095 — microbiology — Posted on 2022-11-11
2485 The rVSV-EBOV vaccine provides limited cross-protection against Sudan virus in guinea pigs
Cao, W.; He, S.; Liu, G.; Schulz, H.; Emeterio, K.; Chan, M.; Tierney, K.; Azaransky, K.; Soule, G.; Tailor, N.; Salawudeen, A.; Nichols, R.; Fusco, J.; Safronetz, D.; Banadyga, L.
10.1101/2022.11.11.516195 — microbiology — Posted on 2022-11-11
2487 Modeling multiphage-bacteria kinetics to predict phage therapy potency and longevity
Yu, Z.; Luong, T.; Banuelos, S.; Sue, A.; Horn, M. A.; Ryu, H.; Roach, D. R.; Segal, R.; Huang, Q.
10.1101/2022.11.11.516137 — microbiology — Posted on 2022-11-11
2490 Attenuated humoral responses in HIV infection after SARS-CoV-2 vaccination are linked to global B cell defects and cellular immune profiles
Touizer, E.; Alrubbayi, A.; Ford, R.; Hussain, N.; Pereyra Gerber, P.; Shum, H.-L.; Rees-Spear, C.; Muir, L.; Gea-Mallorqui, E.; Kopycinski, J.; Jankovic, D.; Pinder, C.; Fox, T. A.; Williams, I.; Mullender, C.; Maan, I.; Waters, L.; Johnson, M.; Madge, S.; Youle, M.; Barber, T.; Burns, F.; Kinloch, S.; Rowland-Jones, S.; Gilson, R.; Matheson, N. J.; Morris, E.; Peppa, D.; McCoy, L. E.
10.1101/2022.11.11.516111 — immunology — Posted on 2022-11-11
2493 A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Thijssen, V.; Hurdiss, D. L.; Debski-Antoniak, O. J.; Spence, M. A.; Franck, C.; Norman, A.; Aggarwal, A.; Mokiem, N. J.; van Dongen, D. A. A.; Vermeir, S. W.; Liu, M.; Chatziandreou, M.; Donselaar, T.; Du, W.; Drulyte, I.; Bosch, B. J.; Snijder, J.; Turville, S. G.; Payne, R. J.; Jackson, C. J.; van Kuppeveld, F. J. M.; Jongkees, S. A. K.
10.1101/2022.11.11.516114 — biochemistry — Posted on 2022-11-11
2494 Development of novel cytoprotective small compounds inhibiting mitochondria-dependent apoptosis
Matsuyama, S.; Matsuyama, M.; Ortega, J.; Fedorov, Y.; Scott-McKean, J.; Muller-Greven, J.; Buck, M.; Adams, D.; Jastrzebska, B.; Greenlee, W.
10.1101/2022.10.12.511987 — cell biology — Posted on 2022-11-11
2496 The single-cell atlas of the murine reproductive tissues during preterm labor
Garcia-Flores, V.; Romero, R.; Peyvandipour, A.; Galaz, J.; Pusod, E.; Panaitescu, B.; Miller, D.; Xu, Y.; Tao, L.; Liu, Z.; Tarca, A. L.; Pique-Regi, R.; Nardhy Gomez-Lopez, N.
10.1101/2022.04.27.489704 — immunology — Posted on 2022-11-11
2497 Ngfr suppresses Lcn2/Slc22a17 signaling, induces neurogenesis and reduces amyloid pathology in the hippocampus of APP/PS1dE9 mouse
Siddiqui, T.; Cosacak, M. I.; popova, S.; Bhattarai, P.; Lee, A. J.; Min, Y.; Wang, X.; Allen, M.; Is, O.; Atasavum, Z. T.; Vardarajan, B. N.; Santa-Maria, I.; tosto, g.; Mayeux, R.; Ertekin-Taner, N.; Kizil, C.
10.1101/2022.08.20.504608 — neuroscience — Posted on 2022-11-11
2498 Predictive link between systemic metabolism and cytokine signatures in the brain of apolipoprotein E ϵ4 mice
Fleeman, R. M.; Snyder, A. M.; Kuhn, M. K.; Chan, D. C.; Smith, G. C.; Crowley, N. A.; Arnold, A. C.; Proctor, E. A.
10.1101/2022.02.11.480074 — physiology — Posted on 2022-11-11
2499 Adipose tissue mitochondrial respiration in Atlantic salmon: implications for sex-dependent life-history variation
Prokkola, J. M.; Wagner, A.; Koskinen, E.; Debes, P. V.; House, A.; Asheim, E. R.; Primmer, C. R.; Pirinen, E.; Aykanat, T.
10.1101/2022.07.25.501389 — physiology — Posted on 2022-11-11
2502 Identification of functional immune and neuronal tumor cells in glioma
Curry, R. N.; McDonald, M. F.; Ma, Q.; Meyer, J.; Aiba, I.; Lozzi, B.; Cervantes, A.; Ko, Y.; Luna-Figueroa, E.; Choi, D.-J.; Lee, Z.-F.; Jing, J.; Harmanci, A. O.; Rosenbaum, A.; He, P.; Mohila, C.; Jalali, A.; Noebels, J.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2022.11.05.515316 — cancer biology — Posted on 2022-11-11
2504 In-vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma
Kaushik, A.; Burroughs, L. K.; Tarangelo, A.; Ragavan, M.; Wu, C.-Y.; Li, X.; Ahumada, K.; Tcheuyap, V. T.; Saatchi, F.; Do, Q.; Yong, C.; Rosales, T.; Stevens, C.; Rao, A. D.; Faubert, B.; Pachnis, P.; Zacharias, L. G.; Vu, H.; Cai, F.; Mathews, T. P.; Slusher, B. S. P.; Kapur, P.; Sun, X.; Merritt, M.; Brugarolas, J.; DeBerardinis, R. J.
10.1101/2022.10.31.514397 — cancer biology — Posted on 2022-11-11
2506 Cancer phylogenetic tree inference at scale from 1000s of single cell genomes
Salehi, S.; Dorri, F.; Chern, K.; Kabeer, F.; Rusk, N.; Funnell, T.; Williams, M. J.; Lai, D.; Andronescu, M.; Campbell, K. R.; McPherson, A.; Aparicio, S.; Roth, A.; Shah, S. P.; Bouchard-Cote, A.
10.1101/2020.05.06.058180 — bioinformatics — Posted on 2022-11-11
2508 The systematic assessment of completeness of public metadata accompanying omics studies
Huang, Y.-N.; Rajesh, A.; Ayyala, R.; Sarkar, A.; Guo, R.; Ling, E.; Nakashidze, I.; Wong, M. Y.; Hu, J.; Yu, D.; Peng, Q.; Scheg, G.; Patel, K. K.; Ramesh, T.; Wang, K.; Yadav, A.; Liu, F.; Mehta, J. H.; Boldirev, G.; Nosov, A.; Chang, Y.; Abedalthagafi, M. S.; Mangul, S.
10.1101/2021.11.22.469640 — bioinformatics — Posted on 2022-11-11
2509 Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms
Pividori, M.; Lu, S.; Li, B.; Su, C.; Johnson, M. E.; Wei, W.-Q.; Feng, Q.; Namjou, B.; Kiryluk, K.; Kullo, I.; Luo, Y.; Sullivan, B. D.; Voight, B. F.; Skarke, C.; Ritchie, M. D.; Grant, S. F. A.; Greene, C. S.
10.1101/2021.07.05.450786 — bioinformatics — Posted on 2022-11-11
2511 CryoEM reveals unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors
Kschonsak, M.; Jao, C. C.; Arthur, C. P.; Rohou, A. L.; Bergeron, P.; Ortwine, D.; McKerrall, S. J.; Hackos, D. H.; Deng, L.; Chen, J.; Peter, D. S.; Volgraf, M.; Wright, M.; Payandeh, J.; Ciferri, C.; Tellis, J. C.
10.1101/2022.11.10.515983 — bioengineering — Posted on 2022-11-11
2512 Mechanism for kinetic polarity revealed by FtsZ from a cell wall-less bacterium Spiroplasma
Chakraborty, J.; Poddar, S. M.; Dutta, S.; Bahulekar, V.; Harne, S.; SRINIVASAN, R.; Gayathri, P.
10.1101/2022.10.13.512043 — biochemistry — Posted on 2022-11-11
2513 Bat teeth illuminate the diversification of mammalian tooth classes
Sadier, A.; Anthwal, N.; Krause, A.; Dessalles, R.; Lake, M.; Bentolila, L.; Haase, R.; Nieves, N.; Santana, S.; Sears, K. E.
10.1101/2021.12.05.471324 — evolutionary biology — Posted on 2022-11-11
2514 Germinal Centers Convergent Evolution and B cell Recirculation in Human Lymph Nodes
Pelissier, A.; Stratigopoulou, M.; Donner, N.; Dimitriadis, E.; Bende, R. J.; Guikema, J. E.; Martinez, M. R.; van Noesel, C. J. M.
10.1101/2022.11.09.463832 — evolutionary biology — Posted on 2022-11-11
2517 Corruption of DNA End-Joining in Mammalian Chromosomes by Progerin Expression as Revealed by a Model Cell Culture System
Joudeh, L. A.; DiCintio, A. J.; Ries, M. R.; Gasperson, A. S.; Griffin, K. E.; Robbins, V. P.; Bonner, M.; Nolan, S.; Black, E.; Waldman, A. S.
10.1101/2022.07.18.500488 — molecular biology — Posted on 2022-11-11
2518 Rapid bacterial and fungal successional dynamics in first year after Chaparral wildfire
Pulido-Chavez, M. F.; Randolph, J. W. J.; Zalman, C.; Larios, L.; Homyak, P. M.; Glassman, S. I.
10.1101/2021.12.07.471678 — microbiology — Posted on 2022-11-11
2519 Sex-biasing influence of autism-associated Ube3a gene overdosage at connectomic, behavioral and transcriptomic levels
Montani, C.; Pagani, M.; De Guzman, E.; Balasco, L.; Alvino, F.; De Felice, A.; Galbusera, A.; Nickl-Jockstat, T.; Lau, P.; Borsotti, N.; Pasqualetti, M.; Mattioni, L.; Provenzano, G.; Bozzi, Y.; Lombardo, M.; Gozzi, A.
10.1101/2022.10.25.513747 — neuroscience — Posted on 2022-11-11
2523 A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta
Carter, B.; Huang, P.; Liu, G.; Liang, Y.; Lin, P. J. C.; Peng, B.-H.; McKay, L.; Dimitrakakis, A.; Hsu, J.; Tat, V.; Saenkham-Huntsinger, P.; Chen, J.; Kaseke, C.; Gaiha, G. D.; Xu, Q.; Griffiths, A.; Tam, Y. K.; Tseng, C.-T. K.; Gifford, D. K.
10.1101/2022.09.23.509206 — immunology — Posted on 2022-11-11
2525 Automatic antibiotic resistance prediction in Klebsiella pneumoniae based on MALDI-TOF mass spectra
Guerrero-Lopez, A.; Sevilla-Salcedo, C.; Candela, A.; Hernandez-Garcia, M.; Cercenado, E.; Olmos, P. M.; Canton, R.; Munoz, P.; Gomez-Verdejo, V.; del Campo, R.; Rodriguez-Sanchez, B.
10.1101/2021.10.04.463058 — microbiology — Posted on 2022-11-11
2526 In-silico enrichment of bacterial plasmids by chromosomal depletion using nanopore adaptive sampling
Ulrich, J.-U.; Epping, L.; Pilz, T.; Walther, B.; Stingl, K.; Semmler, T.; Renard, B. Y.
10.1101/2022.10.03.510741 — bioinformatics — Posted on 2022-11-11
2528 Systematic mining and genetic characterization of regulatory factors for wheat spike development
Lin, X.; Xu, Y.; Wang, D.; Yang, Y.; Zhang, X.; Bie, X.; Wang, H.; Jiang, J.; Ding, Y.; Lu, F.; Zhang, X.; Zhang, X.; Fu, X.; Xiao, J.
10.1101/2022.11.11.516122 — plant biology — Posted on 2022-11-11
2530 Medicago truncatula ABCG40 is a cytokinin importer negatively regulating lateral root density and nodule number
Jamruszka, T.; Banasiak, J.; Pawela, A.; Jarzyniak, K.; Xia, J.; Biala, W.; Plackova, L.; Iacobini, F. R.; Novak, O.; Geisler, M. M.; Jasinski, M.
10.1101/2022.11.10.516000 — plant biology — Posted on 2022-11-11
2531 A call to rethink the cognitive benefits of physical exercise
Ciria, L. F.; Romn-Caballero, R.; Vadillo, M. A.; Holgado, D.; Luque-Casado, A.; Perakakis, P.; Sanabria, D.
10.1101/2022.02.15.480508 — neuroscience — Posted on 2022-11-11
2536 Adaptive foraging behaviour increases vulnerability to climate change
Gauzens, B.; Rosenbaum, B.; Kalinkat, G.; Boy, T.; Jochum, M.; Kortsch, S.; O'Gorman, E. J.; Brose, U.
10.1101/2021.05.05.442768 — ecology — Posted on 2022-11-11
2538 Ultra-fast joint-genotyping with SparkGOR
Gudbjartsson, H.; Isleifsson, H. b.; Ragnarsson, B.; Guimaraes, R.; Wu, H.; Olafsdottir, H.; Stefasson, S. K.
10.1101/2022.10.25.513331 — bioinformatics — Posted on 2022-11-11
2540 Ciliary tip actin dynamics regulate the cadenceof photoreceptor disc formation
Megaw, R.; Moye, A.; Zhang, Z.; Newton, F.; McPhie, F.; Murphy, L. C.; McKie, L.; He, F.; Jungnickel, M. K.; von Kriegsheim, A.; Machesky, L.; Wensel, T. G.; Mill, P.
10.1101/2022.11.10.516020 — cell biology — Posted on 2022-11-11
2541 EV Fingerprinting: Resolving extracellular vesicle heterogeneity using multi-parametric flow cytometry
von Lersner, A. K.; Fernandes, F. C. L.; Ozawa, P. M. M.; Vagner, T.; Lima, S. M.; Sung, B. H.; Wehbe, M.; Franze, K.; Wilson, J. T.; Irish, J. M.; Weaver, A.; Di Vizio, D.; Zijlstra, A.
10.1101/2022.11.10.515864 — cell biology — Posted on 2022-11-11
2547 The H3K4me1 histone mark recruits DNA repair to functionally constrained genomic regions in plants
Quiroz, D.; Lopez-Mateos, D.; Zhao, K.; Pierce, A.; Ortega, L.; Ali, A.; Carbonell-Bejerano, P.; Yarov-Yarovoy, V.; Monroe, G.
10.1101/2022.05.28.493846 — genomics — Posted on 2022-11-11
2548 De-differentiation and Proliferation of Artery Endothelial Cells Drive Coronary Collateral Development
Arolkar, G.; K, S.; Wang, H.; Gonzalez, K. M.; Kumar, S.; Rios Coronado, P. E.; Woo, J. Y.; Red-Horse, K.; Das, S.
10.1101/2022.07.27.501689 — developmental biology — Posted on 2022-11-11
2551 Time as a supervisor: temporal regularity and auditory object learning
DiTullio, R. W.; Piasini, E.; Chaudhari, P.; Balasubramanian, V.; Cohen, Y. E.
10.1101/2022.11.10.515986 — neuroscience — Posted on 2022-11-10
2559 CryoEM reveals unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors
Kschonsak, M.; Jao, C. C.; Arthur, C. P.; Rohou, A. L.; Bergeron, P.; Ortwine, D.; McKerrall, S. J.; Hackos, D. H.; Deng, L.; Chen, J.; Peter, D. S.; Volgraf, M.; Wright, M.; Payandeh, J.; Tellis, J. C.; Ciferri, C.
10.1101/2022.11.10.515983 — bioengineering — Posted on 2022-11-10
2563 Extensive genomic divergence among 61 strains of Chlamydia psittaci
Sachse, K.; Holzer, M.; Vorimore, F.; Barf, L.-M.; Lamkiewicz, K.; Sachse, C.; Laroucau, K.; Marz, M.
10.1101/2022.11.10.515926 — genomics — Posted on 2022-11-10
2567 Cell autonomous requirement of imprinted XCI inextra-embryonic polar trophoblast cells
Wang, F.; Chander, A.; Yoon, Y.; Wallingford, M.; Espejo-Serrano, C.; Bustos, F.; Findlay, G. M.; Mager, J.; Bach, I.
10.1101/2022.11.10.515976 — developmental biology — Posted on 2022-11-10
2568 Development of a mouse model for postresectional liver failure.
van Mierlo, K. M. C.; van Himbeeck, C.; Lebrun, V.; Jansen, P. L. M.; Dejong, C. H. C.; Leclercq, I. A.; Damink, S. W. M. O.; Schaap, F. G.
10.1101/2022.11.10.515992 — cell biology — Posted on 2022-11-10
2570 The FXR agonist obeticholic acid does not stimulate liver regeneration in hepatectomized mice.
van Mierlo, K. M. C.; Dahrenmoller, C.; Lebrun, V.; Jansen, P. L. M.; Dejong, C. H. C.; Leclercq, I. A.; Olde Damink, S. W. M.; Schaap, F. G.
10.1101/2022.11.10.515905 — cell biology — Posted on 2022-11-10
2572 Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes
Casado, P.; Rio-Machin, A.; Miettinen, J. J.; Bewicke-Copley, F.; Rouault-Pierre, K.; Krizsan, S.; Parsons, A.; Rajeeve, V.; Miraki-Moud, F.; Taussig, D. C.; Bödör, C.; Gribben, J.; Heckman, C.; Fitzgibbon, J.; Cutillas, P. R.
10.1101/2022.11.10.515949 — molecular biology — Posted on 2022-11-10
2573 A new LD protein, ApoL6 disrupts the Perilipin 1-HSL interaction to inhibit lipolysis
Wang, Y.; Nguyen, H. P.; Xue, P.; Xie, Y.; Yi, D.; Lin, F.; Viscarra, J. A.; Ibe, N. U.; Duncan, R. E.; Sul, H. S.
10.1101/2022.11.10.516022 — molecular biology — Posted on 2022-11-10
2574 Identification of small molecules with virus growth enhancement properties
Garcia-Murria, M. J.; Gadea-Salom, L.; Moreno, S.; Zaragoza, O.; Brun, A.; Mingarro, I.; Martinez-Gil, L.
10.1101/2022.11.08.515589 — microbiology — Posted on 2022-11-10
2576 An update on eukaryotic viruses revived from ancient permafrost
Alempic, J.-M.; Lartigue, A.; Goncharov, A. E.; Grosse, G.; Strauss, J.; Tikhonov, A. N.; Fedorov, A. N.; Poirot, O.; Legendre, M.; Santini, S.; Abergel, C.; Claverie, J.-M.
10.1101/2022.11.10.515937 — microbiology — Posted on 2022-11-10
2579 The effect of wheat genotype on its microbiome is more evident in roots than rhizosphere and is strongly influenced by time
Quiza, L.; Tremblay, J.; Page, A.; Greer, C.; Pozniak, C.; Li, R.; Haug, B.; Hemmingsen, S.; St-Arnaud, M.; Yergeau, E.
10.1101/2022.11.10.515967 — microbiology — Posted on 2022-11-10
2581 Integration of exogenous and endogenous co-stimulatory signals by CAR-Tregs
Rosado-Sanchez, I.; Haque, M.; Salim, K.; Speck, M.; Fung, V.; Boardman, D.; Mojibian, M.; Raimondi, G.; Levings, M. K.
10.1101/2022.11.10.516049 — immunology — Posted on 2022-11-10
2582 ALiCE: A versatile, high yielding and scalable eukaryotic cell-free protein synthesis (CFPS) system
Das Gupta, M.; Flaskamp, Y.; Roentgen, R.; Juergens, H.; Armero Gimenez, J.; Albrecht, F.; Hemmerich, J.; Ahmad Arfi, Z.; Neuser, J.; Spiegel, H.; Yeliseev, A.; Song, L.; Qiu, J.; Williams, C.; Finnern, R.
10.1101/2022.11.10.515920 — biochemistry — Posted on 2022-11-10
2583 HIV-1 infection reduces NAD capping of host cell snRNA and snoRNA
Benoni, B.; Benoni, R.; Trylcova, J.; Grab, K.; Paces, J.; Weber, J.; Stanek, D.; Kowalska, J.; Bednarova, L.; Keckesova, Z.; Gahurova, L.; Cahova, H.
10.1101/2022.11.10.515957 — biochemistry — Posted on 2022-11-10
2584 Nucleotide-free structures of Kif20A illuminate the atypical allostery in this mitotic kinesin-6
Ranaivoson, F. M.; Crozet, V.; Benoit, M.; Mohammed Khalid, A. A.; Kikuti, C.; Sirkia, H.; El Marjou, A.; Asenjo, A.; Sosa, H.; Schmidt, C.; Rosenfeld, S.; Houdusse, A.
10.1101/2022.11.10.515925 — biochemistry — Posted on 2022-11-10
2587 An intranasal self-amplifying RNA SARS-CoV-2 vaccine produces durable respiratory and systemic immunity
Jennewein, M. F.; Beaver, S.; Battisti, P.; Bakken, J.; Hanson, D.; Mohamath, R.; Singh, J.; Cross, N.; Reed, S.; Gerhardt, A.; Casper, C.; Voigt, E. A.
10.1101/2022.11.10.515993 — immunology — Posted on 2022-11-10
2589 A highly contiguous genome assembly of red perilla (Perilla frutescens) domesticated in Japan
Tamura, K.; Sakamoto, M.; Tanizawa, Y.; Mochizuki, T.; Matsushita, S.; Kato, Y.; Ishikawa, T.; Okuhara, K.; Nakamura, Y.; Bono, H.
10.1101/2022.09.16.508052 — plant biology — Posted on 2022-11-10
2591 Limited emergence of resistance to Integrase strand transfer inhibitors (INSTIs) in HIV-experienced patients failing dolutegravir-based antiretroviral therapy: Cross-sectional analysis from a Northeast Nigerian cohort
Abdullahi, A.; Kida, I. M.; Maina, U. A.; Ibrahim, A. H.; Mshelia, J.; Wisso, H.; Adamu, A.; Onyemata, J. E.; Yusuph, H.; Aliyu, S.; Charurat, M.; Abimiku, A.; AbelerDorner, L.; Fraser, C.; Bonsall, D.; Kemp, S.; Gupta, R. K.
10.1101/2022.11.08.515598 — molecular biology — Posted on 2022-11-10
2592 "Self-inactivating" rabies viruses are susceptible to loss of their intended attenuating modification
Jin, L.; Matsuyama, M.; Sullivan, H. A.; Zhu, M.; Lavin, T. K.; Hou, Y.; Lea, N. E.; Pruner, M. T.; Dam Ferdinez, M. L.; Wickersham, I. R.
10.1101/550640 — neuroscience — Posted on 2022-11-10
2593 Off-manifold coding in visual cortex revealed by sleep
de Oliveira, E. F.; Kim, S.; Qiu, T. S.; Peyrache, A.; Batista-Brito, R.; Sjulson, L.
10.1101/2022.06.10.495710 — neuroscience — Posted on 2022-11-10
2594 A stable, distributed code for cue value in mouse cortex during reward learning
Ottenheimer, D. J.; Hjort, M. M.; Bowen, A. J.; Steinmetz, N. A.; Stuber, G. D.
10.1101/2022.07.13.499930 — neuroscience — Posted on 2022-11-10
2599 Ultra-fast joint-genotyping with SparkGOR
Gudbjartsson, H.; Isleifsson, H. b.; Ragnarsson, B.; Guimaraes, R.; Wu, H.; Olafsdottir, H.; Stefasson, S. K.
10.1101/2022.10.25.513331 — bioinformatics — Posted on 2022-11-10
2600 Probing lung function at high spatiotemporal resolution using a novel crystal ribcage
Banerji, R.; Grifno, G. N.; Shi, L.; Smolen, D.; LeBourdais, R.; Muhvich, J.; Eberman, C.; Hiller, B.; Lee, J.; Regan, K.; Zheng, S.; Zhang, S. S.; Pihl, R.; Traber, K.; Ligresti, G.; Mizgerd, J. P.; Suki, B.; Nia, H. T.
10.1101/2022.10.28.514251 — bioengineering — Posted on 2022-11-10
2601 Semi-quantitative detection of pseudouridine modifications and type I/II hypermodifications in human mRNAs using direct and long-read sequencing
Tavakoli, S.; Nabizadehmashhadtoroghi, M.; Makhamreh, A.; Gamper, H.; McCormick, C. A.; Rezapour, N.; Hou, Y.-M.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2021.11.03.467190 — genomics — Posted on 2022-11-10
2607 Ehrlichia ruminantium uses its transmembrane protein Ape to adhere to host bovine aortic endothelial cells
Pinarello, V.; Bencurova, E.; Marcelino, I.; Gros, O.; Puech, C.; Bhide, M.; Vachiery, N.; MEYER, D. F.
10.1101/2021.06.15.447525 — microbiology — Posted on 2022-11-10
2608 Gut microbiota bacterial strain richness is species specific and limits therapeutic engraftment
Chen-Liaw, A.; Aggarwala, V.; Mogno, I.; Haifer, C.; Eggers, J.; Li, Z.; Helmus, D.; Hart, A.; Wehkamp, J.; Lamouse-Smith, E.; Kerby, R. L.; Rey, F. E.; Colombel, J. F.; Kamm, M.; Borody, T. J.; Grinspan, A.; Paramsothy, S.; Kaakoush, N.; Dubinsky, M. C.; Faith, J. J.
10.1101/2022.11.01.514782 — microbiology — Posted on 2022-11-10
2609 TREM1+ regulatory myeloid cells expand in steatohepatitis-HCC and associate with poor prognosis and therapeutic resistance to immune checkpoint blockade
Giraud, J.; Chalopin, D.; Ramel, E.; Boyer, T.; Zouine, A.; Derieppe, M.-A.; Larmonier, N.; Adotevi, O.; Le Bail, B.; Blanc, J.-F.; Chiche, L.; Nikolski, M.; Saleh, M.
10.1101/2022.11.09.515839 — immunology — Posted on 2022-11-10
2610 Selective integration of diverse taste inputs within a single taste modality
Deere, J. U.; Sarkissian, A. A.; Yang, M.; Uttley, H. A.; Martinez Santana, N.; Nguyen, L.; Ravi, K.; Devineni, A. V.
10.1101/2022.02.09.479727 — neuroscience — Posted on 2022-11-10
2611 Adolescent binge drinking leads to long lasting changes in cortical microcircuits in mice
Sicher, A. R.; Starnes, W. D.; Griffith, K. R.; Dao, N. C.; Smith, G. C.; Brockway, D. F.; Crowley, N. A.
10.1101/2022.08.02.502367 — neuroscience — Posted on 2022-11-10
2612 The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling
Alexander, K. D.; Ramachandran, S.; Biswas, K.; Lambert, C. M.; Russell, J.; Oliver, D.; Armstrong, W.; Rettler, M.; Doitsidou, M.; Benard, C.; Francis, M. M.
10.1101/2022.10.21.512874 — neuroscience — Posted on 2022-11-10
2613 Neuronal E93 regulates metabolic homeostasis
Yip, C.; Wyler, S.; Yamazaki, S.; Rothenfluh, A.; Lee, S.; YOU, Y.-J.; Elmquist, J.
10.1101/2022.10.06.511196 — physiology — Posted on 2022-11-10
2616 Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation
Hilligan, K. L.; Oyesola, O. O.; Namasivayam, S.; Howard, N.; Clancy, C. S.; Oland, S. D.; Garza, N. L.; Lafont, B. A. P.; Johnson, R. F.; Mayer-Barber, K. D.; Sher, A.; Loke, P.
10.1101/2022.11.09.515832 — immunology — Posted on 2022-11-10
2617 TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions
Griffin, P. T.; Kane, A. E.; Trapp, A.; Li, J.; Arnold, M.; Poganik, J. R.; McNamara, M. S.; Meer, M. V.; Hoffman, N.; Amorim, J.; Tian, X.; MacArthur, M. R.; Mitchell, S. J.; Mueller, A. L.; Carmody, C.; Vera, D. L.; Kerepesi, C.; Noren Hooten, N.; Mitchell, J. R.; Evans, M. K.; Gladyshev, V. N.; Sinclair, D. A.
10.1101/2021.10.25.465725 — genomics — Posted on 2022-11-10
2618 Germinal Centers Convergent Evolution and B cell Recirculation in Human Lymph Nodes
Pelissier, A.; Stratigopoulou, M.; Donner, N.; Dimitriadis, E.; Bende, R. J.; Martinez, M. R.; Guikema, J. E.; van Noesel, C. J. M.
10.1101/2022.11.09.463832 — evolutionary biology — Posted on 2022-11-10
2619 Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow in a butterfly
Rodriguez de Cara, M. A.; Jay, P.; Rougemont, Q.; Chouteau, M.; Whibley, A.; Huber, B.; Piron-Prunier, F.; Ramos, R. R.; Freitas, A. V. L.; Salazar, C.; Silva-Brandao, K. L.; Torres, T. T.; Joron, M.
10.1101/2021.09.29.462348 — evolutionary biology — Posted on 2022-11-10
2620 The genome of the bee louse fly reveals deep convergences in the evolution of social inquilinism
Legout, H.; Ogereau, D.; Carcaud, J.; Filee, J.; Garnery, L.; Gilbert, C.; Requier, F.; Sandoz, J.-C.; Yassin, A.; Bastide, H.
10.1101/2022.11.08.515706 — evolutionary biology — Posted on 2022-11-10
2621 Estimating abundance of a recovering transboundary brown bear population with capture-recapture models
Vanpe, C.; Piedallu, B.; Quenette, P.-Y.; Sentilles, J.; Queney, G.; Palazon, S.; Jordana, I. A.; Jato, R.; Irurtia, M. M. E.; de la Torre, J. S.; Gimenez, O.
10.1101/2021.12.08.471719 — ecology — Posted on 2022-11-10
2622 High-risk microbial signatures are associated with severe parasitemia in controlled Plasmodium infections of both humans and rhesus macaques
Gustin, A. T.; Broedlow, C. A.; Hager, K.; Coronado, E.; Wangari, S.; Iwayama, N.; Ahrens, C. Y.; Garrison, W. D.; Guerriero, K. A.; De Paris, K.; Gale, M.; Klatt, N. R.; Kublin, J. G.; Manuzak, J. A.
10.1101/2022.09.06.506695 — microbiology — Posted on 2022-11-10
2623 deCLUTTER2+ pipeline to analyze calcium traces in a novel stem cell model for ventral midbrain patterned astrocytes
Grochowska, M. M.; Ferraro, F.; Carreras Mascaro, A.; Natale, D.; Winkelaar, A.; Boumeester, V.; Breedveld, G. J.; Bonifati, V.; Mandemakers, W.
10.1101/2022.11.08.515628 — neuroscience — Posted on 2022-11-10
2629 Massive proteogenomic reanalysis of publicly available proteomic datasets of human tissues in search for protein recoding via adenosine-to-inosine RNA editing
Levitsky, L. I.; Ivanov, M. V.; Goncharov, A. O.; Kliuchnikova, A. A.; Bubis, J. A.; Lobas, A. A.; Solovyeva, E. M.; Pyatnitskiy, M. A.; Ovchinnikov, R. K.; Kukharsky, M. S.; Farafonova, T. E.; Novikova, S. E.; Zgoda, V. G.; Tarasova, I. A.; Gorshkov, M. V.; Moshkovskii, S. A.
10.1101/2022.11.10.515815 — bioinformatics — Posted on 2022-11-10
2637 Uncovering Cross-Cohort Molecular Features with Multi-Omics Integration Analysis
Jiang, M.-Z.; Aguet, F.; Ardlie, K.; Chen, J.; Cornell, E.; Cruz, D.; Durda, P.; Gabriel, S. B.; Gerszten, R. E.; Guo, X.; Johnson, C. W.; Kasela, S.; Lange, L. A.; Lappalainen, T.; Liu, Y.; Reiner, A. P.; Smith, J.; Sofer, T.; Taylor, K. D.; Tracy, R. P.; VanDenBerg, D. J.; Wilson, J. G.; Rich, S. S.; Rotter, J. I.; Love, M. I.; Raffield, L. M.; Li, Y.
10.1101/2022.11.10.515908 — genomics — Posted on 2022-11-10
2638 Genetic drivers of chromosomal integron stability
Richard, E.; Darracq, B.; Littner, E.; Vit, C.; Whiteway, C.; Bos, J.; Fournes, F.; Garriss, G.; Conte, V.; Lapaillerie, D.; Parissi, V.; Rousset, F.; Skovgaard, O.; Bikard, D.; Rocha, E.; Mazel, D.; Loot, C.
10.1101/2022.08.03.502626 — genetics — Posted on 2022-11-10
2643 Adjuvant effects of multifunctional transcription factor and BCG ‎target YB-1: exogenous YB-1 enhances specific antibody ‎production in vivo and protects mice against lethal E. coli ‎challenge
Shepelyakovskaya, A. O.; Alekseeva, L.; Meshcheryoakova, E. A.; Boziev, K.; Tsitrina, A.; Ivanov, V.; Brovko, F.; Kotelevtsev, Y.; Lathe, R.; Laman, A. G.
10.1101/2022.11.09.515841 — immunology — Posted on 2022-11-10
2644 TREM1+ regulatory myeloid cells expand in steatohepatitis-HCC and associate with poor prognosis and therapeutic resistance to anti-PD-1 blockade
Giraud, J.; Chalopin, D.; Ramel, E.; Boyer, T.; Zouine, A.; Derieppe, M.-A.; Larmonier, N.; Adotevi, O.; Le Bail, B.; Blanc, J.-F.; Chiche, L.; Nikolski, M.; Saleh, M.
10.1101/2022.11.09.515839 — immunology — Posted on 2022-11-10
2647 A comparative atlas of single-cell chromatin accessibility in the human brain
Li, Y. E.; Preissl, S.; Miller, M.; Johnson, N. D.; Wang, Z.; Jiao, H.; Zhu, C.; Wang, Z.; Xie, Y.; Poirin, O.; Kern, C.; Pinto-Duarte, A.; Tian, W.; Siletti, K.; Emerson, N.; Osteen, J.; Lucero, J.; Lin, L.; Yang, Q.; Espinoza, S.; Zhu, Q.; Zemke, N.; Yanny, A. M.; Nyhus, J.; Dee, N.; Casper, T.; Shapovalova, N.; Hirschstein, D.; Hodge, R. D.; Linnarsson, S.; Bakken, T. E.; Levi, B.; Keene, C. D.; Shang, J.; Lein, E. S.; Wang, A.; Behrens, M. M.; Ecker, J. R.; Ren, B.
10.1101/2022.11.09.515833 — neuroscience — Posted on 2022-11-10
2649 BatCount: A software program to count moving animals
Bentley, I.; Kuczynska, V.; Eddington, V. M.; Armstrong, M.; Kloepper, L. N.
10.1101/2022.11.09.515821 — zoology — Posted on 2022-11-10
2651 Engineering of NEMO as calcium indicators with ultra-high dynamics and sensitivity
Li, J.; Shang, Z.; Chen, J.-H.; Gu, W.; Yao, L.; Yang, X.; Sun, X.; Wang, L.; Wang, T.; Liu, S.; Li, J.; Hou, T.; Xing, D.; Gill, D. L.; Li, J.; Wang, S.-Q.; Hou, L.; Zhou, Y.; Tang, A.-H.; Zhang, X.; Wang, Y.
10.1101/2022.08.23.504677 — synthetic biology — Posted on 2022-11-10
2652 Overruled by nature: A plastic response to an ecological regime shift disconnects a gene and its trait
Besnier, F.; Skaala, O.; Wennevik, V.; Ayllon, F.; Utne, K.; Fjeldheim, P. t.; Andersen, K. C.; Knutar, S.; Glover, K. A.
10.1101/2022.10.27.514021 — genetics — Posted on 2022-11-10
2655 Perception of Rigidity in Three- and Four-Dimensional Spaces
He, D.; Nguyen, D.-T.; Ogmen, H.; Nishina, S.; Yazdanbakhsh, A.
10.1101/2022.11.09.515874 — neuroscience — Posted on 2022-11-10
2656 Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits
Zhang, J.; Zhang, M.; Wang, Q.; Wen, H.; Liu, Z.; Wang, F.; Wang, Y.; Yao, F.; Song, N.; Kou, Z.; Li, Y.; Guo, F.; ZHU, S.
10.1101/2022.11.09.514853 — neuroscience — Posted on 2022-11-10
2657 Identification of a unique transcriptomic signature associated with islet amyloidosis
Barovic, M.; Steinmeyer, K.; Kipke, N.; Schoeniger, E.; Friedland, D.; Marzetta, F.; Forberger, A.; Baretton, G.; Weitz, J.; Aust, D.; Ibberson, M.; Distler, M.; Schulte, A.; Solimena, M.
10.1101/2022.11.09.515784 — systems biology — Posted on 2022-11-10
2659 Breast cancer mutations HER2 V777L and PIK3CA H1047R activate the p21/CDK4/6/Cyclin D1 axis driving tumorigenesis and drug resistance.
Cheng, X.; Sun, Y.; Highkin, M.; Vemalapally, N.; Jin, X.; Zhou, B.; Prior, J. L.; Tipton, A. R.; Li, S.; Iliuk, A.; Achilefu, S.; Hagemann, I. S.; Edwards, J. R.; Bose, R.
10.1101/2022.11.09.515796 — cancer biology — Posted on 2022-11-10
2660 Quisinostat is a brain-penetrant radiosensitizer in glioblastoma
Lo Cascio, C.; Margaryan, T.; Melendez, E. L.; McNamara, J. B.; White, C. I.; Knight, W.; Ganta, S.; Opachich, Z.; Yoo, W.; Sanai, N.; Mehta, S.; Tovmasyan, A.
10.1101/2022.11.09.515859 — cancer biology — Posted on 2022-11-10
2662 Hybran: Hybrid Reference Transfer and ab initio Prokaryotic Genome Annotation
Elghraoui, A.; Gunasekaran, D.; Ramirez-Busby, S. M.; Bishop, E.; Valafar, F.
10.1101/2022.11.09.515824 — bioinformatics — Posted on 2022-11-10
2667 Long-read genome assemblies reveals a cis-regulatory landscape associated with phenotypic divergence in two sister Siniperca fishes
Tu, G.; Chen, Q.; Zhang, X.; Jiang, R.; Zhang, L.; Lai, C.; Yan, Z.; Lv, Y.; Weng, S.-P.; Zhang, L.; He, J.; Wang, M.
10.1101/2022.11.09.515789 — genomics — Posted on 2022-11-10
2669 Germinal Centers Convergent Evolution and B cell Recirculation in Human Lymph Nodes
Pelissier, A.; Stratigopoulou, M.; Donner, N.; Dimitriadis, E.; Bende, R. J.; Martinez, M. R.; Guikema, J. E.; van Noesel, C. J. M.
10.1101/2022.11.09.463832 — evolutionary biology — Posted on 2022-11-10
2673 Effects of lactate, super-GDF9 and low oxygen tension during biphasic in vitro maturation on the bioenergetic profiles of mouse cumulus-oocyte-complex
Akin, N.; Ates, G.; von Mengden, L.; Herta, A.-C.; Meriggioli, C.; Billooye, K.; Stocker, W. A.; Ghesquiere, B.; Harrison, C. A.; Klamt, F.; Massie, A.; Smitz, J.; Anckaert, E.
10.1101/2022.11.09.514870 — developmental biology — Posted on 2022-11-10
2677 A novel deep learning pipeline for cell typing and phenotypic marker quantification in multiplex imaging
Markovits, E.; Dankovich, T.; Gluskin, R.; Weiss, I.; Gutwillig, A.; Dicker, T.; Dagan, S.; Elran, R.; Arbiv, B.; Shachaf, Y.; Bart, A.; Debby, A.; Asher, N.; Ben-Betzalel, G.; Shapira-Frommer, R.; Barshack, I.; Zelichov, O.
10.1101/2022.11.09.515776 — immunology — Posted on 2022-11-10
2678 FLASH and Conventional Radiation Induce Differential Immune Responses in Diffuse Intrinsic Pontine Glioma, Highlighting Potential for Combination Immunotherapy
Padilla, O.; Minns, H. E.; Wei, H.-J.; Webster-Carrion, A.; Tazhibi, M.; McQuillan, N. M.; Zhang, X.; Yeh, R.; Zhang, Z.; Hei, T. K.; Szalontay, L.; Pavisic, J.; Garty, G.; Garvin, J. H.; Canoll, P. D.; Vanpouille-Box, C.; Menon, V.; Olah, M.; Wu, C.-C.; Rabadan, R.; Gartrell, R. D.
10.1101/2022.11.09.515507 — immunology — Posted on 2022-11-10
2679 Tumor-specific CD4 T cells instruct monocyte differentiation in pancreatic ductal adenocarcinoma
Patterson, M. T.; Burrack, A. L.; Xu, Y.; Schmiechen, Z. C.; Schrank, P. R.; Kennedy, A. E.; Firulyova, M. M.; Miller, E. A.; Cruz-Hinojoza, E.; Zaitsev, K.; Williams, J. W.; Stromnes, I. M.
10.1101/2022.11.09.515858 — immunology — Posted on 2022-11-10
2681 Plant secondary metabolite-dependent plant-soil feedbacks can improve crop yield in the field
Gfeller, V.; Waelchli, J.; Pfister, S.; Deslandes-Herold, G.; Mascher, F.; Glauser, G.; Aeby, Y.; Mestrot, A.; Robert, C. A. M.; Schlaeppi, K.; Erb, M.
10.1101/2022.11.09.515047 — plant biology — Posted on 2022-11-10
2682 Stomatal density affects rice mesophyll cell size and shape and modulates a conserved pattern of cells through the leaf
Sloan, J. M.; Im-Chai, S.; Ngai, Q. Y.; Xiao, Y.; Armand, J.; Wilson, M. J.; Zhu, X.-G.; Fleming, A. J.
10.1101/2022.11.09.515764 — plant biology — Posted on 2022-11-10
2687 Quantitative imaging of gene therapy delivery vehicles using CEST-NMR/MRI
Lam, B.; Velasquez, M.; Velasquez-Mao, A. J.; Godines, K.; AlGhuraibawi, W.; Wendland, M.; Pelton, J. G.; Vandsburger, M.
10.1101/2022.11.09.515733 — bioengineering — Posted on 2022-11-10
2697 Survivin is a mechanosensitive cell cycle regulator in vascular smooth muscle cells
Biber, J. C.; Sullivan, A.; Brazzo, J. A.; Krajnik, A.; Heo, Y.; Poppenberg, K. E.; Tutino, V. M.; Heo, S.-J.; Kolega, J.; Lee, K.; Bae, Y.
10.1101/2022.11.09.515885 — cell biology — Posted on 2022-11-10
2698 Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair
Korsten, G.; Pelle, R. A.; Hoogenberg, B.; Kampinga, H. H.; Kapitein, L. C.
10.1101/2022.11.09.515785 — cell biology — Posted on 2022-11-10
2699 Adaptive preservation of orphan ribosomal proteins in chaperone-stirred condensates
Ali, A.; Garde, R.; Schaffer, O. C.; Bard, J. A. M.; Husain, K.; Keyport Kik, S.; Davis, K. A.; Luengo-Woods, S.; Drummond, D. A.; Squires, A. H.; Pincus, D.
10.1101/2022.11.09.515856 — cell biology — Posted on 2022-11-10
2700 Through the eye to the brain: Modulating locus coeruleus-mediated arousal via pupil-based neurofeedback
Meissner, S. N.; Baechinger, M.; Kikkert, S.; Imhof, J.; Missura, S.; Carro Dominguez, M.; Wenderoth, N.
10.1101/2022.08.26.505388 — neuroscience — Posted on 2022-11-10
2702 A phloem-localized Arabidopsis metacaspase (AtMC3) improves drought tolerance
Pitsili, E.; Rodriguez- Trevino, R.; Ruiz-Solani, N.; Demir, F.; Kastanaki, E.; Dambire, C.; de Pedro, R.; Vercammen, D.; Salguero-Linares, J.; Hall, H.; Mantz, M.; Schuler, M.; Tuominen, H.; Van Breusegem, F.; Valls, M.; Munne-Bosch, S.; Holdsworth, M.; Huesgen, P.; Rodriguez-Villalon, A.; Coll, N. S.
10.1101/2022.11.09.515759 — plant biology — Posted on 2022-11-10
2704 EUGENe: A Python toolkit for predictive analyses of regulatory sequences
Klie, A.; Stites, H.; Jores, T.; Solvason, J. J.; Farley, E. K.; Carter, H.
10.1101/2022.10.24.513593 — bioinformatics — Posted on 2022-11-09
2705 Immune Contexture of Isocitrate Dehydrogenase stratified Human Gliomas
Gupta, P.; Dang, M.; Oberai, S.; Peshoff, M. M.; Milam, N.; Ahmed, A.; Bojja, K.; Tran, T. M.; Cox, K.; Shehwana, H.; Matsuoka, C. K.; Li, J.; Gumin, J.; Goldman, A.; Seth, S. A.; Maheshwari, A.; Lang, F. F.; Navin, N. E.; Heimberger, A. B.; Dwyer, K. C.; Wang, L.; Bhat, K. P.
10.1101/2022.11.08.514794 — immunology — Posted on 2022-11-09
2707 Challenges in antibody structure prediction
Fernandez-Quintero, M. L.; Kokot, J.; Waibl, F.; Fischer, A.-L. M.; Quoika, P.; Deane, C. M.; Liedl, K.
10.1101/2022.11.09.515600 — bioinformatics — Posted on 2022-11-09
2708 A live cell protein complementation assay for ORFeome-wide probing of human HOX interactomes
Jia, Y.; Reboulet, J.; Gillet, B.; Hughes, S.; Forcet, C.; Tribollet, V.; Hadj Sleiman, N.; Kundlacz, C.; Vanacker, J.-M.; Bleicher, F.; Merabet, S.
10.1101/2022.11.09.515750 — molecular biology — Posted on 2022-11-09
2709 Neurobehavioral precursors of compulsive cocaine-seeking in dual fronto-striatal circuits
Jones, J.; Belin-Rauscent, A.; Jupp, B.; Fouyssac, M.; Sawiak, S.; Zuhlsdorff, K.; Zhukovsky, P.; Velazquez, C.; Robbins, T.; Everitt, B. J.; Belin, D.; Dalley, J.
10.1101/2022.11.09.515779 — neuroscience — Posted on 2022-11-09
2710 Modular, cement-free, customized headpost and connector-chamber implants for macaques
Psarou, E.; Vezoli, J.; Schölvinck, M. L.; Ferracci, P.-A.; Zhang, Y.; Grothe, I.; Roese, R.; Fries, P.
10.1101/2022.11.09.515849 — neuroscience — Posted on 2022-11-09
2715 Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Forrest, M. P.; Dos Santos, M.; Piguel, N. H.; Wang, Y. Z.; Yoon, S.; Bagchi, V. A.; Hawkins, N. A.; Dionisio, L. E.; Simkin, D.; Martin-de-Saavedra, M. D.; Gao, R.; Horan, K. E.; George, A. L.; LeDoux, M.; Kearney, J. A.; Savas, J.; Penzes, P.
10.1101/2022.11.09.515866 — neuroscience — Posted on 2022-11-09
2718 Estimation of Vertex-wise Sulcal Width Maps on Cortical Surfaces
Fernandez-Pena, A.; Navas-Sanchez, F. J.; Martin de Blas, D.; Marcos-Vidal, L.; M. Gordaliza, P.; Martinez-Tejada, I.; Janssen, J.; Carmona, S.; Desco, M.; Aleman-Gomez, Y.
10.1101/2022.11.09.515775 — neuroscience — Posted on 2022-11-09
2723 Demographic Reporting and Phenotypic Exclusion in fNIRS
Kwasa, J.; Peterson, H. M.; Jones, L.; Karrobi, K.; Parker, T.; Nickerson, N.; Wood, S.
10.1101/2022.11.08.515730 — neuroscience — Posted on 2022-11-09
2725 Flexible, Scalable, High Channel Count Stereo-Electrode for Recording in the Human Brain
Lee, K.; Paulk, A. C.; Ro, Y. G.; Cleary, D. R.; Tonsfeldt, K. J.; Kfir, Y.; Pezaris, J.; Tchoe, Y.; Lee, J.; Bourhis, A. M.; Vatsyayan, R.; Russman, S. M.; Yang, J. C.; Baohan, A.; Richardson, M.; Williams, Z. M.; Fried, S.; Raslan, A.; Halgren, E.; Cash, S. S.; Dayeh, S. A.
10.1101/2022.11.08.515705 — neuroscience — Posted on 2022-11-09
2727 Computational design of BclxL inhibitors that target transmembrane domain interactions
Duart, G.; Elazar, A.; Weinstein, J.; Gadea-Salom, L.; Ortiz-Mateu, J.; Fleishman, S.; Mingarro, I.; Martinez-Gil, L.
10.1101/2022.11.09.515782 — biochemistry — Posted on 2022-11-09
2730 The structural, dynamical and biochemical characterizations of Verticillium dahliae pectate lyase, VdPelB, highlight its specificities
Safran, J.; Ung, V.; Bouckaert, J.; Habrylo, O.; Molinie, R.; Fontaine, J.-X.; Lemaire, A.; Voxeur, A.; Pilard, S.; Pau-Roblot, C.; Mercadante, D.; Pelloux, J.; Senechal, F.
10.1101/2022.11.09.515409 — biochemistry — Posted on 2022-11-09
2731 Ageing in a collective: The impact of ageing individuals on social network structure
Siracusa, E. R.; Pereira, A. S.; Bohr Brask, J.; Negron-Del Valle, J. E.; Phillips, D.; Cayo Biobank Research Unit, ; Platt, M. L.; Higham, J. P.; Snyder-Mackler, N.; Brent, L. J. N.
10.1101/2022.08.10.503309 — animal behavior and cognition — Posted on 2022-11-09
2732 Complementary Ribo-seq approaches map the translatome and provide a small protein census in the foodborne pathogen Campylobacter jejuni
Froschauer, K.; Svensson, S. L.; Gelhausen, R.; Fiore, E.; Kible, P.; Klaude, A.; Kucklick, M.; Fuchs, S.; Eggenhofer, F.; Engelmann, S.; Backofen, R.; Sharma, C. M.
10.1101/2022.11.09.515450 — genomics — Posted on 2022-11-09
2734 A nematode model to evaluate microdeletion phenotype expression
Antkowiak, K. R.; Coskun, P.; Noronha, S. T.; Tavella, D.; Massi, F.; Ryder, S. P.
10.1101/2022.11.09.515676 — genetics — Posted on 2022-11-09
2735 Case-only exome variation analysis of severe alcohol dependence using a multivariate hierarchical gene clustering approach
Gentry, A. E.; Alexander, J.; Ahangari, M.; Peterson, R. E.; Miles, M. F.; Bettinger, J. C.; Davies, A. G.; Groteweil, M.; Bacanu, S.-A.; Kendler, K. S.; Riley, B. P.; Webb, B. T.
10.1101/2022.03.16.484608 — genetics — Posted on 2022-11-09
2736 Characterization of TMEM43 as a novel ion channel
Jang, M. W.; Won, J.; Han, Y.-E.; Lee, J.-H.; Han, A.-r.; Kim, H. M.; Lee, C. J.
10.1101/2022.11.08.515259 — molecular biology — Posted on 2022-11-09
2738 FUS modulates the level of ribosomal RNA modifications by regulating a subset of snoRNA expression
Gawade, K.; Plewka, P.; Hafner, S. J.; Lund, A. H.; Marchand, V.; Motorin, Y.; Szczesniak, M. W.; Raczynska, K. D.
10.1101/2022.11.09.515592 — molecular biology — Posted on 2022-11-09
2739 Plant pathogenic Ralstonia phylotypes evolved divergent respiratory strategies and behaviors to thrive in xylem
Truchon, A. N.; Dalsing, B. L.; Khokhani, D.; MacIntyre, A.; McDonald, B. R.; Ailloud, F.; Klassen, J.; Gonzalez-Orta, E. T.; Currie, C.; Prior, P.; Lowe-Power, T. M.; Allen, C.
10.1101/2022.11.09.515861 — microbiology — Posted on 2022-11-09
2740 Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission
Sapiro, A. L.; Hayes, B. M.; Volk, R. F.; Zhang, J. Y.; Brooks, D. M.; Martyn, C.; Radkov, A.; Zhao, Z.; Kinnersley, M.; Secor, P. R.; Zaro, B. W.; Chou, S.
10.1101/2022.11.09.515847 — microbiology — Posted on 2022-11-09
2741 Shigella serotypes associated with carriage in humans establish persistent infection in zebrafish
Torraca, V.; Brokatzky, D.; Miles, S. L.; Chong, C. E.; De Silva, P. M.; Baker, S.; Jenkins, C.; Holt, K. E.; Baker, K. S.; Mostowy, S.
10.1101/2022.11.08.515620 — microbiology — Posted on 2022-11-09
2747 Expanding the molecular and morphological diversity of Apusomonadida, a deep-branching group of gliding bacterivorous protists
Torruella, G.; Galindo, L. J.; Moreira, D.; Ciobanu, M.; Heiss, A. A.; Yubuki, N.; Kim, E.; Lopez-Garcia, P.
10.1101/2022.11.09.515670 — microbiology — Posted on 2022-11-09
2749 Biofilms preserve transmissibility of a multi-drug resistance plasmid
Metzger, G. A.; Ridenhour, B. J.; France, M.; Gliniewicz, K.; Millstein, J.; Settles, M. L.; Forney, L. . J.; Stalder, T.; Top, E. M.
10.1101/2022.04.18.488688 — microbiology — Posted on 2022-11-09
2750 Differential requirement for IRGM proteins during tuberculosis infection in mice
Wilburn, K. M.; Meade, R. K.; Heckenberg, E. M.; Dockterman, J.; Coers, J.; Sassetti, C. M.; Olive, A. J.; Smith, C. M.
10.1101/2022.11.09.515519 — microbiology — Posted on 2022-11-09
2754 Peyers Patch B cells undergo cell death via neutrophil-released toxic DNA following sterile tissue injury
Tuz, A. A.; Beer, A.; Gallert, M.; Ttoouli, D.; Ghosh, S.; Sata, S. P.; Kraus, A.; Zwirnlein, F.; Kaygusuz, V.; Lakovic, V.; Qefalia, A.; Antler, M.; Korste, S.; Kaltwasser, B.; Abdelrahman, H.; Mohamud-Yusuf, A.; Wang, C.; Haeusler, L.; Lueong, S.; Stenzel, M.; Frank, B.; Koehrmann, M.; Siveke, J.; Totzeck, M.; Hoffmann, D.; Grueneboom, A.; Hagemann, N.; Hasenberg, A.; Sickmann, A.; Chen, J.; Hermann, D. M.; Gunzer, M.; Singh, V.
10.1101/2022.11.09.515763 — immunology — Posted on 2022-11-09
2755 Endosomal GLUT3 is essential for alternative macrophage signaling, polarization, and function
Yu, D.-M.; Zhao, J.; Lee, E. E.; Rose, E. K.; Mahapatra, R.; Choe, J.-Y.; Abel, E. D.; Wang, R. C.
10.1101/2022.11.09.515804 — immunology — Posted on 2022-11-09
2756 Asymmetric cell division safeguards memory CD8 T cell development
Graebnitz, F.; Stark, D.; Shlesinger, D.; Petkidis, A.; Borsa, M.; Yermanos, A.; Carr, A.; Barandun, N.; Wehling, A.; Balaz, M.; Schroeder, T.; Oxenius, A.
10.1101/2022.11.08.515624 — immunology — Posted on 2022-11-09
2757 Tailored synthetic sRNAs dynamically tune multilayer genetic circuits
Velazquez Sanchez, A. K.; Klopprogge, B.; Zimmermann, K.-H.; Ignatova, Z.
10.1101/2022.11.09.515794 — synthetic biology — Posted on 2022-11-09
2759 LambdaPP: Fast and accessible protein-specific phenotype predictions
Olenyi, T.; Marquet, C.; Heinzinger, M.; Kroeger, B.; Nikolova, T.; Saendig, P.; Bernhofer, M.; Schuetze, K.; Littmann, M.; Mirdita, M.; Steinegger, M.; Dallago, C.; Rost, B.
10.1101/2022.08.04.502750 — bioinformatics — Posted on 2022-11-09
2764 Near-Physiological in vitro Assembly of 50S Ribosomes Involves Parallel Pathways
Dong, X.; Doerfel, L. K.; Sheng, K.; Rabuck-Gibbons, J. N.; Popova, A. M.; Lyumkis, D.; Williamson, J. R.
10.1101/2022.11.09.515862 — biochemistry — Posted on 2022-11-09
2765 CineFinch: An animated female zebra finch for studying courtship interactions
Phaniraj, N.; Joshi, S.; Trimbake, P.; Pujari, A.; Ramadurai, S.; Kalra, S.; Ratnaparkhi, N.; Rajan, R.
10.1101/2022.11.02.514933 — animal behavior and cognition — Posted on 2022-11-09
2767 TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions
Griffin, P. T.; Kane, A. E.; Trapp, A.; Li, J.; Arnold, M.; Poganik, J. R.; McNamara, M. S.; Meer, M. V.; Hoffman, N.; Amorim, J.; Tian, X.; MacArthur, M. R.; Mitchell, S. J.; Mueller, A. L.; Carmody, C.; Vera, D. L.; Kerepesi, C.; Noren Hooten, N.; Mitchell, J. R.; Evans, M. K.; Gladyshev, V. N.; Sinclair, D. A.
10.1101/2021.10.25.465725 — genomics — Posted on 2022-11-09
2770 SARS-CoV-2 ORF8 limits expression levels of Spike antigen.
Kim, I.-J.; Lee, Y.-h.; Khalid, M. M.; Zhang, Y.; Ott, M.; Verdin, E.
10.1101/2022.11.09.515752 — microbiology — Posted on 2022-11-09
2771 Infection and chronic disease activate a brain-muscle signaling axis that regulates muscle performance
Yang, S.; Tian, M.; Dai, Y.; Feng, S.; Wang, Y.; Chhangani, D.; Ou, T.; Li, W.; Yang, Z.; McAdow, J.; Rincon-Limas, D.; Yin, X.; Tai, W.; Chen, G.; Johnson, A. N.
10.1101/2020.12.20.423533 — immunology — Posted on 2022-11-09
2776 Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of alpha-synuclein inclusions
Lam, I.; Ndayisaba, A.; Lewis, A. J.; Fu, Y.; Sagredo, G. T.; Zaccagnini, L.; Sandoe, J.; Sanz, R. L.; Vahdatshoar, A.; Martin, T. D.; Morshed, N.; Ichihashi, T.; Tripathi, A.; Ramalingam, N.; Oettgen-Suazo, C.; Bartels, T.; Schabinger, M.; Hallacli, E.; Jiang, X.; Verma, A.; Tea, C.; Wang, Z.; Hakozaki, H.; Yu, X.; Hyles, K.; Park, C.; Theunissen, T. W.; Wang, H.; Jaenisch, R.; Lindquist, S.; Stevens, B.; Stefanova, N.; Wenning, G.; Luk, K. C.; Sanchez Pernaute, R.; Gomez-Esteban, J. C.; Felsky, D.; Kiyota, Y.; Sahni, N.; Yi, S. S.; Chung, C.-Y.; Stahlberg, H.; Ferrer, I.; Schoneberg, J.; Ell
10.1101/2022.11.08.515615 — neuroscience — Posted on 2022-11-09
2778 Impact of variants of concern on SARS-CoV-2 viral dynamics in non-human primates.
Marc, A.; Marlin, R.; Donati, F.; Prague, M.; Kerioui, M.; Herate, C.; Alexandre, M.; Dereuddre-bosquet, N.; Bertrand, J.; Contreras, V.; Behillil, S.; Maisonnasse, P.; Van Der Werf, S.; Le Grand, R.; Guedj, J.
10.1101/2022.11.09.515748 — microbiology — Posted on 2022-11-09
2779 Cross-neutralization and viral fitness of SARS-CoV-2 Omicron sublineages
Xia, H.; Yeung, J.; Kalveram, B.; Bills, C. J.; Chen, J. Y.-C.; Kurhade, C.; Zou, j.; Widen, S. G.; Mann, B. R.; Kondor, R. J.; Davis, T. C.; Zhou, B.; Wentworth, D. E.; Xie, X.; Shi, P.-Y.
10.1101/2022.11.08.515725 — microbiology — Posted on 2022-11-09
2781 The genome of the bee louse fly reveals deep convergences in the evolution of social inquilinism
Legout, H.; Ogereau, D.; Filee, J.; Garnery, L.; Gilbert, C.; Requier, F.; Yassin, A.; Bastide, H.
10.1101/2022.11.08.515706 — evolutionary biology — Posted on 2022-11-09
2783 A new concept in antiviral drug design
Mackenzie-Kludas, C.; Wu, W.-Y.; Jin, B.; McKimm-Breschkin, J. L.; Seah, E. L.; Jones, P.; Fairmaid, E.; Tai, C. M. K.; Oh, D. Y.; Jenkins, P.; Hurt, A. C.; Brown, L. E.
10.1101/2022.11.08.515737 — microbiology — Posted on 2022-11-09
2784 Investigation of the neural effects of memory training to reduce false memories in older adults: Univariate and multivariate analyses
Turney, I. C.; Chamberlain, J. D.; Hakun, J. G.; Steinkrauss, A. C.; Ross, L. A.; Kirchhoff, B. A.; Dennis, N. A.
10.1101/2022.11.08.515495 — neuroscience — Posted on 2022-11-09
2786 Microglial process dynamics enhance neuronal activity by shielding GABAergic synaptic inputs
Haruwaka, K.; Ying, Y.; Liang, Y.; Umpierre, A. D.; Yi, M.-H.; Kremen, V.; Chen, T.; Xie, T.; Dong, H.; Worrell, G.; Wu, L.-J.
10.1101/2022.11.08.515728 — neuroscience — Posted on 2022-11-09
2787 Whole-Brain fMRI Functional Connectivity Signatures Predict Sustained Emotional Experience in Naturalistic Contexts
Xu, S.; Zhang, Z.; Li, L.; Zhou, Y.; Lin, D.; Zhang, L.; Huang, G.; Liu, X.; Becker, B.; Liang, Z.
10.1101/2022.11.08.515743 — neuroscience — Posted on 2022-11-09
2790 Signature morpho-electric properties of diverse GABAergic interneurons in the human neocortex
Lee, B.; Dalley, R.; Miller, J. A.; Chartrand, T.; Close, J.; Mann, R.; Mukora, A.; Ng, L.; Alfiler, L.; Baker, K.; Bertagnolli, D.; Brouner, K.; Casper, T.; Csajbok, E.; Dee, N.; Donadio, N.; Driessens, S. L. W.; Egdorf, T.; Enstrom, R.; Galakhova, A. A.; Gary, A.; Gelfand, E.; Goldy, J.; Hadley, K.; Heistek, T. S.; Hill, D.; Johansen, N.; Jorstad, N.; Kim, L.; Kocsis, A. K.; Kruse, L.; Kunst, M.; Leon, G.; Long, B.; Mallory, M.; Maxwell, M.; McGraw, M.; McMillen, D.; Melief, E. J.; Molnar, G.; Mortrud, M. T.; Newman, D.; Nyhus, J.; Opitz-Araya, X.; Pham, T.; Pom, A.; Potekhina, L.; Rajanbabu
10.1101/2022.11.08.515739 — neuroscience — Posted on 2022-11-09
2791 Translational fusion of terpene synthases enhances metabolic flux by increasing protein stability
Cheah, L. C.; Liu, L.; Stark, T.; Plan, M.; Peng, B.; Lu, Z.; Schenk, G.; Sainsbury, F.; Vickers, C. E.
10.1101/2022.11.08.515726 — synthetic biology — Posted on 2022-11-09
2792 Knockdown of mitochondrial atp1 mRNA by a custom-designed pentatricopeptide repeat protein alters F1Fo ATP synthase
Yang, F.; Vincis Pereira Sanglard, L. M.; Lee, C.-P.; Stroeher, E.; Singh, S.; Oh, G. G. K.; Millar, A. H.; Small, I. D.; Colas des Francs-Small, C.
10.1101/2022.11.08.515711 — plant biology — Posted on 2022-11-09
2794 Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors
Hoffman, S. E.; Dowrey, T. W.; Martin, C. V.; Bi, K.; Titchen, B. M.; Johri, S.; DelloStritto, L.; Patel, M.; Mackichan, C.; Inga, S.; Chen, J.; Grimaldi, G.; Napolitano, S.; Wakiro, I.; Wu, J.; Yeung, J.; Rotem, A.; Shannon, E.; Clancy, T. E.; Wang, J.; Denning, S.; Brais, L.; Huang, Y.; Kao, K. Z.; Rodig, S.; Hornick, J. L.; Vigneau, S.; Park, J.; Kulke, M. H.; Chan, J.; Van Allen, E. M.; Murphy, G. J.
10.1101/2022.11.08.515538 — cancer biology — Posted on 2022-11-09
2795 Flap-enabled next-generation capture (FENGC): precision targeted single-molecule profiling of epigenetic heterogeneity, chromatin dynamics, and genetic variation
Zhou, M.; Nabilsi, N. H.; Wang, A.; Gauthier, M.-P. L.; Murray, K. O.; Azari, H.; Owens, W. S.; Newman, J. R. B.; Pardo-Palacios, F. J.; Conesa, A.; Riva, A.; Clanton, T. L.; Reynolds, B. A.; Concannon, P.; Brant, J. O.; Bacher, R.; Kladde, M. P.
10.1101/2022.11.08.515732 — cancer biology — Posted on 2022-11-09
2796 Single Pixel Reconstruction Imaging: taking confocal imaging to the extreme
Streckaite, S.; Frolov, D.; Chmeliov, J.; Gelzinis, A.; Ilioaia, C.; Rimsky, S.; van Grondelle, R.; Valkunas, L.; Gall, A.; Robert, B.
10.1101/2022.11.08.515455 — biophysics — Posted on 2022-11-09
2798 Technical Note: STRATIS: A Cloud-enabled Software Toolbox for Radiotherapy and Imaging Analysis
Apte, A.; LoCastro, E.; Iyer, A.; Jiang, J.; Oh, J. H.; Veeraraghavan, H.; Dave, A.; Deasy, J. O.
10.1101/2022.11.08.515686 — bioinformatics — Posted on 2022-11-09
2799 The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from Males
Morena da Silva, F.; Lim, S.; Cabrera, A. R.; Schrems, E. R.; Jones, R. G.; Rosa-Caldwell, M.; Washington, T. A.; Murach, K. A.; Greene, N. P.
10.1101/2022.11.08.515691 — bioinformatics — Posted on 2022-11-09
2802 Pipeline for transferring annotations between proteins beyond globular domains
Martinez-Perez, E.; Pajkos, M.; Tosatto, S. C. E.; Gibson, T. J.; Dosztanyi, Z.; Marino-Buslje, C.
10.1101/2022.11.08.515674 — bioinformatics — Posted on 2022-11-09
2803 First superferromagnetic remanence characterization and scan optimization for super-resolution Magnetic Particle Imaging
Fung, K. L. B.; Colson, C.; Bryan, J.; Saayujya, C.; Mokkarala-Lopez, J.; Hartley, A.; Yousuf, K.; Kuo, R.; Lu, Y.; Fellows, B. D.; Chandrasekharan, P.; Conolly, S. M.
10.1101/2022.11.08.515719 — bioengineering — Posted on 2022-11-09
2805 Endometrial decidualization status modulates endometrial perivascular complexity and trophoblast outgrowth in gelatin hydrogels
Zambuto, S. G.; Theriault, H.; Jain, I.; Crosby, C.; Pintescu, I.; Chiou, N. Y.; Zoldan, J.; Underhill, G.; Clancy, K. B.; Harley, B.
10.1101/2022.11.08.515680 — bioengineering — Posted on 2022-11-09
2807 Genomics reveals introgression and purging of deleterious mutations in the Arabian leopard (Panthera pardus nimr)
Riano, G.; Fontsere, C.; de Manuel, M.; Talavera, A.; Burriel-Carranza, B.; Tejero-Cicuendez, H.; AlGethami, R. H. M.; Shobrak, M.; Marques-Bonet, T.; Carranza, S.
10.1101/2022.11.08.515636 — genomics — Posted on 2022-11-09
2813 Trait diversity metrics can perform well with highly incomplete datasets
Stewart, K.; Carmona, C. P.; Clements, C.; Venditti, C.; Tobias, J. A.; Gonzalez-Suarez, M.
10.1101/2022.11.08.515633 — ecology — Posted on 2022-11-09
2815 Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA
Kleinehr, J.; Daniel, K.; Günl, F.; Janowski, J.; Brunotte, L.; Liebmann, M.; Behrens, M.; Gerdemann, A.; Klotz, L.; Esselen, M.; Humpf, H.-U.; Ludwig, S.; Hrincius, E. R.
10.1101/2022.11.09.515749 — microbiology — Posted on 2022-11-09
2816 Asymmetric cell division safeguards memory CD8 T cell development
Graebnitz, F.; Stark, D.; Shlesinger, D.; Petkidis, A.; Borsa, M.; Yermanos, A.; Carr, A.; Barandun, N.; Wehling, A.; Balaz, M.; Schroeder, T.; Oxenius, A.
10.1101/2022.11.08.515624 — immunology — Posted on 2022-11-09
2817 Correction of age-associated defects in dendritic cell functions enables CD4+ T cells to eradicate tumors in the elderly
Zhivaki, D.; Borriello, F.; Kennedy, S.; Evavold, C. L.; Bahleda, K. M.; Chapman, K. L.; Zanoni, I.; Kagan, J. C.
10.1101/2022.11.08.515695 — immunology — Posted on 2022-11-09
2818 deCLUTTER2+ pipeline to analyze calcium traces in a novel stem cell model for ventral midbrain patterned astrocytes
Grochowska, M. M.; Ferraro, F.; Carreras Mascaro, A.; Natale, D.; Winkelaar, A.; Boumeester, V.; Breedveld, G. J.; Bonifati, V.; Mandemakers, W.
10.1101/2022.11.08.515628 — neuroscience — Posted on 2022-11-09
2819 Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of alpha-synuclein inclusions
Lam, I.; Ndayisaba, A.; Lewis, A. J.; Fu, Y.; Sagredo, G. T.; Zaccagnini, L.; Sandoe, J.; Sanz, R. L.; Vahdatshoar, A.; Martin, T. D.; Morshed, N.; Ichihashi, T.; Tripathi, A.; Ramalingam, N.; Oettgen-Suazo, C.; Bartels, T.; Schabinger, M.; Hallacli, E.; Jiang, X.; Verma, A.; Tea, C.; Wang, Z.; Hakozaki, H.; Yu, X.; Hyles, K.; Park, C.; Theunissen, T. W.; Wang, H.; Jaenisch, R.; Lindquist, S.; Stevens, B.; Stefanova, N.; Wenning, G.; Luk, K. C.; Sanchez Pernaute, R.; Gomez-Esteban, J. C.; Felsky, D.; Kiyota, Y.; Sahni, N.; Yi, S. S.; Chung, C.-Y.; Stahlberg, H.; Ferrer, I.; Schoneberg, J.; Ell
10.1101/2022.11.08.515615 — neuroscience — Posted on 2022-11-09
2821 NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice
Zhang, R.; Mao, W.; Niu, L.; Bao, W.; Wang, Y.; Yang, Z.; Zhu, Y.; Song, H.; Chen, J.; Li, G.; Cai, M.; Yuan, Z.; Dong, J.; Zhang, M.; Xiong, N.; Wei, J.; Dong, Z.
10.1101/2022.11.08.515655 — neuroscience — Posted on 2022-11-09
2823 Molecular diversity and connectivity of accessory olfactory system neurons
Prakash, N.; Matos, H. Y.; Sebaoui, S.; Tsai, L.; Tran, T.; Aromolaran, A.; Atrachji, I.; Campbell, N.; Goodrich, M.; Hernandez-Pineda, D.; Herrero, M.; Hirata, T.; Lischinsky, J.; Martinez, W.; Torii, S.; Yamashita, S.; Sokolowski, K.; Esumi, S.; Kawasawa, Y. I.; Hashimoto-Torii, K.; Jones, K. S.; Corbin, J. G.
10.1101/2022.11.08.515541 — neuroscience — Posted on 2022-11-09
2826 Multilevel Modelling of Gaze from Hearing-impaired Listeners following a Realistic Conversation
Shiell, M. M.; Christensen, J. H.; Skoglund, M.; Keidser, G.; Zaar, J.; Rotger-Griful, S.
10.1101/2022.11.08.515622 — neuroscience — Posted on 2022-11-09
2827 GABAergic neuron-to-glioma synapses in diffuse midline gliomas
Barron, T.; Yalcin, B.; Mochizuki, A.; Cantor, E.; Shamardani, K.; Tlais, D.; Franson, A.; Lyons, S.; Mehta, V.; Maleki Jahan, S.; Taylor, K. R.; Keough, M. B.; Xu, H.; Su, M.; Quezada, M. A.; Woo, P. J.; Fisher, P. G.; Campen, C. J.; Partap, S.; Koschmann, C.; Monje, M.
10.1101/2022.11.08.515720 — neuroscience — Posted on 2022-11-09
2829 Individual differences in volitional social motivation in male and female mice following social stress.
Navarrete, J.; Schneider, K. N.; Smith, B. M.; Goodwin, N. L.; Zhang, Y. Y.; Gross, E.; Tsai, V. S.; Heshmati, M.; Golden, S. A.
10.1101/2022.11.08.515718 — neuroscience — Posted on 2022-11-09
2830 Tailoring confocal microscopy for in-cell photophysiology studies
Storti, M.; Hsine, H.; UWIZEYE, C.; Bastien, O.; Yee, D.; Chevalier, F.; Giustini, C.; Beal, D.; Decelle, J.; Curien, G.; TOLLETER, D.; Finazzi, G.
10.1101/2022.11.08.515612 — plant biology — Posted on 2022-11-09
2832 The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers
Ishii, A.; Shan, J.; Sheng, X.; Kim, E.; Watanabe, A.; Yokono, M.; Noda, C.; Song, C.; Murata, K.; Liu, Z.; Minagawa, J.
10.1101/2022.11.08.515661 — plant biology — Posted on 2022-11-09
2833 Thermal acclimation in a non-migratory songbird occurs via changes to thermogenic capacity, but not conductance
Schweizer, R. M.; Romero, A.; Tobalske, B. W.; Semenov, G.; Carling, M. D.; Rice, A. M.; Taylor, S. A.; Cheviron, Z. A.
10.1101/2022.11.08.515677 — physiology — Posted on 2022-11-09
2835 Emergence of ion-channel mediated electrical oscillations in E. coli biofilms
Akabuogu, E. U.; Martorelli, V.; Krasovec, R.; Roberts, I. S.; Waigh, T. A.
10.1101/2022.11.09.515771 — biophysics — Posted on 2022-11-09
2836 Lysosomal calcium loading promotes arrhythmias by potentiating ryanodine receptor release
Meng, Z.; Capel, R.-A.; Bose, S. J.; Bosch, E.; Jong, S. d.; Planque, R.; Galione, A.; Burton, R. A.; Bueno-Orovio, A.
10.1101/2022.11.09.515777 — biophysics — Posted on 2022-11-09
2843 Persulfidation of DJ-1 : Mechanism and Consequences
Galardon, E.; Mathas, N.; Padovani, D.; Le Corre, L.; Poncet, G.; Dairou, J.
10.1101/2022.11.09.515774 — biochemistry — Posted on 2022-11-09
2844 Association Between Polygenic Risk Score And Gut Microbiome Of Multiple Sclerosis
Elsayed, N. S.; Valenzuela, R. K.; Kitchner, T.; Le, T.; Mayer, J.; Tang, Z.-Z.; Bayanagari, V. R.; Lu, Q.; Aston, P.; Anantharaman, K.; Shukla, S. K.
10.1101/2022.11.07.515482 — genetics — Posted on 2022-11-09
2846 Mapping human social brain specialisation beyond the neuron using multimodal imaging in human infants
Siddiqui, M.; Pinti, P.; Brigadoi, S.; Lloyd-Fox, S.; Elwell, C. E.; Johnson, M. H.; Tachtsidis, I.; Jones, E. J.
10.1101/2022.11.08.514512 — developmental biology — Posted on 2022-11-09
2847 Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells
Kobayashi-Ishihara, M.; Smutna, K. F.; Alonso, F. E.; Argilaguet, J.; Esteve-Codina, A.; Geiger, K.; Genesca, M.; Grau-Exposito, J.; Duran-Castells, C.; Rogenmoser, S.; Böttcher, R.; Jungfleisch, J.; Oliva, B.; Martinez, J. P.; Li, M.; David, M.; Yamagishi, M.; Ruiz-Riol, M.; Brander, C.; Tsunetsugu-Yokota, Y.; Buzon, M. J.; Diez, J.; Meyerhans, A.
10.1101/2022.11.09.512793 — immunology — Posted on 2022-11-09
2848 Sodium channel endocytosis drives axon initial segment plasticity
FREAL, A.; Jamann, N.; Ten Bos, J.; Jansen, J.; Petersen, N.; Ligthart, T.; Hoogenraad, C.; Kole, M. H. P.
10.1101/2022.11.09.515770 — neuroscience — Posted on 2022-11-09
2849 FIRST INSIGHTS IN A NON-RODENT MODEL SPECIES OF THE OLFACTORY LIMBUS. THE RED FOX (Vulpes vulpes) AS A CASE IN POINT
ORTIZ-LEAL, I.; TORRES, M. V.; VARGAS-BARROSO, V.; FIDALGO, L. E.; LOPEZ-BECEIRO, A. M.; LARRIVA-SAHD, J. A.; SANCHEZ-QUINTEIRO, P.
10.1101/2022.11.08.515585 — neuroscience — Posted on 2022-11-09
2850 Different outcomes of neonatal and adult Zika virus infection on startle reflex and prepulse inhibition in mice
Souza, I. N.; Andrade, B. S.; Frost, P. S.; Neris, R. L.; Gavino-Leopoldino, D.; Da Poian, A. T.; Assuncao-Miranda, I.; Figueiredo, C. P.; Clarke, J. R.; Neves, G. A.
10.1101/2022.11.08.515594 — neuroscience — Posted on 2022-11-09
2852 The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain.
Leistner, C.; Wilkinson, M.; Burgess, A.; Goodbody, S.; Xu, Y.; Deuchars, S.; Radford, S. E.; Ranson, N. A.; Frank, R. A. W.
10.1101/2022.11.08.515609 — neuroscience — Posted on 2022-11-09
2853 Sensory tuning in neuronal movement commands
Baumann, M. P.; Bogadhi, A. R.; Denninger, A. F.; Hafed, Z. M.
10.1101/2022.11.08.515621 — neuroscience — Posted on 2022-11-09
2854 Non-invasive disruption of the blood-brain barrier in the marmoset monkey
Szczupak, D.; Choi, S.-H.; Alikaya, A.; Mou, Y.; Silva, A. C.; Schaeffer, D. J.
10.1101/2022.11.08.515696 — neuroscience — Posted on 2022-11-09
2855 Systems-level transcriptional regulation of Caenorhabditis elegans metabolism
Walhout, A. J.; Nanda, S.; Jacques, M.-A.; Wang, W.; Myers, C. L.; Yilmaz, S.
10.1101/2022.11.08.515576 — systems biology — Posted on 2022-11-09
2856 COMPUTATIONAL EVIDENCE FOR MULTI-LAYER CROSSTALK BETWEEN THE CADHERIN-11 AND PDGFR PATHWAYS
Karagoz, Z.; Passanha, F. R.; Robeerst, L.; van Griensven, M.; LaPointe, V.; Carlier, A.
10.1101/2022.11.08.514892 — systems biology — Posted on 2022-11-09
2857 Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver
Thapa, K.; Kadiri, J. J.; Saukkonen, K.; Pennanen, I.; Cai, M.; Savontaus, E.; Rinne, P.
10.1101/2022.11.08.515543 — physiology — Posted on 2022-11-09
2859 Wildflower phenological escape differs by continent and spring temperature
Lee, B. R.; Miller, T.; Rosche, C.; Yang, Y.; Heberling, J. M.; Kuebbing, S. E.; Primack, R. B.
10.1101/2022.09.28.509910 — ecology — Posted on 2022-11-09
2861 Native and invasive populations of the ectomycorrhizal death cap Amanita phalloides are highly sexual but dispersal limited
Golan, J. J.; Adams, C.; Cross, H.; Elmore, H.; Gardes, M.; Glassman, S. I.; Goncalves, S.; Hess, J. I.; Richard, F.; Wang, Y.-W.; Wolfe, B.; Pringle, A.
10.1101/799254 — microbiology — Posted on 2022-11-09
2862 Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture
Risner, K.; Tieu, K. V.; Wang, Y.; Getz, M.; Bakovic, A.; Bhalla, N.; Nathan, S.; Conway, D. E.; Macklin, P.; Narayanan, A.
10.1101/2020.08.12.246389 — microbiology — Posted on 2022-11-09
2867 Infection-Induced Extracellular Vesicles Evoke Neuronal Transcriptional and Epigenetic Changes
Tedford, E.; Badya, N. B.; Laing, C.; Asaoka, N.; Kaneko, S.; Filippi, B. M.; McConkey, G. A.
10.1101/2020.11.26.399345 — microbiology — Posted on 2022-11-09
2869 Joint Instability Causes Catabolic Enzyme Production in Chondrocytes prior to Synovial Cells in Novel Non-Invasive ACL ruptured Mouse Model
Takahata, K.; Arakawa, K.; Enomoto, S.; Usami, Y.; Nogi, K.; Saitou, R.; Ozone, K.; Takahashi, H.; Yoneno, M.; Kokubun, T.
10.1101/2022.05.28.493828 — molecular biology — Posted on 2022-11-09
2870 FLAIRR-seq: A novel method for single molecule resolution of near full-length immunoglobulin heavy chain repertoires
Ford, E. E.; Tieri, D.; Rodriguez, O. L.; Francoeur, N. J.; Soto, J.; Kos, J. T.; Peres, A.; Gibson, W. S.; Silver, C. A.; Deikus, G.; Hudson, E.; Woolley, C. R.; Beckmann, N.; Charney, A.; Mitchell, T. C.; Yaari, G.; Sebra, R. P.; Watson, C. T.; Smith, M. L.
10.1101/2022.09.24.509352 — immunology — Posted on 2022-11-09
2871 Cerebellar contributions to a brainwide network for reversal learning
Verpeut, J. L.; Bergeler, S.; Kislin, M.; Townes, F. W.; Klibaite, U.; Dhanerawala, Z. M.; Hoag, A.; Jung, C.; Lee, J.; Pisano, T. J.; Seagraves, K. M.; Shaevitz, J. W.; Wang, S. S.- H.
10.1101/2021.12.07.471685 — neuroscience — Posted on 2022-11-09
2872 Orexin cells efficiently decode blood glucose dynamics to drive adaptive behavior
Viskaitis, P.; Tesmer, A.; Karnani, M. M.; Arnold, M.; Donegan, D.; Bracey, E.; Grujic, N.; Peleg-Raibstein, D.; Burdakov, D.
10.1101/2022.04.14.488310 — neuroscience — Posted on 2022-11-09
2873 Engineering Escherichia coli to utilize erythritol as sole carbon source
Ba, F.; Ji, X.; Huang, S.; Zhang, Y.; Liu, W.-Q.; Liu, Y.; Ling, S.; Li, J.
10.1101/2022.10.03.510612 — synthetic biology — Posted on 2022-11-09
2874 Intracortical remodelling increases in highly-loaded bone after exercise cessation
da Silva, R. G. C.; Sun, T. C.; Mishra, A. P.; Boyde, A.; Doube, M.; Riggs, C. M.
10.1101/2022.05.06.490923 — physiology — Posted on 2022-11-09
2875 CAPG: Comprehensive Allopolyploid Genotyper
Kulkarni, R.; Zhang, Y.; Cannon, S. B.; Dorman, K. S.
10.1101/2022.04.21.488948 — bioinformatics — Posted on 2022-11-09
2876 Efficient recovery of complete gut phage genomes by combined short- and long- sequencing
Chen, W.; Chen, J.; Sun, C.; Dong, Y.; Jin, M.; Lai, S.; Jia, L.; Zhao, X.; Gao, N. L.; Liu, Z.; Bork, P.; Zhao, X.-M.
10.1101/2022.07.03.498593 — bioinformatics — Posted on 2022-11-09
2877 Potassium regulates axon-oligodendrocyte signaling and metabolic coupling in white matter
Looser, Z. J.; Ravotto, L.; Jung, R. B.; Werner, H. B.; Ruhwedel, T.; Moebius, W.; Bergles, D. E.; Barros, L. F.; Nave, K.-A.; Weber, B.; Saab, A. S.
10.1101/2022.11.08.515614 — neuroscience — Posted on 2022-11-09
2879 Cerebellar granule neurons induce Cyclin D1 in an early stage of Huntington's disease
Bauer, S.; Chen, C.-Y.; Jonson, M.; Kaczmarczyk, L.; Magadi, S.; Jackson, W. S.
10.1101/2022.11.08.515613 — bioinformatics — Posted on 2022-11-09
2881 Insular cortex to ventral striatum synapses encode valence of social interaction
Espinosa, P.; Girard, B.; Lucchini, M.; Campanelli, F.; Tiriticco, V.; Bellone, C.
10.1101/2022.11.08.515650 — neuroscience — Posted on 2022-11-09
2886 Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment
Sulit, A. K.; Daigneault, M.; Allen-Vercoe, E.; Silander, O. K.; Hock, B.; McKenzie, J.; Pearson, J.; Frizelle, F. A.; Schmeier, S.; Purcell, R.
10.1101/2022.04.26.489473 — cancer biology — Posted on 2022-11-08
2891 Functional differentiation of Sec13 paralogs in the euglenozoan protists
Faktorova, D.; Zahonova, K.; Benz, C.; Dacks, J. B.; Field, M. C.; Lukes, J.
10.1101/2022.11.08.515606 — evolutionary biology — Posted on 2022-11-08
2892 Emergent coexistence in multispecies microbial communities
Chang, C.-Y.; Bajic, D.; Vila, J. C. C.; Estrela, S.; Sanchez, A.
10.1101/2022.05.20.492860 — ecology — Posted on 2022-11-08
2894 Proteolysis-free cell migration through crowded environments via mechanical worrying
Driscoll, M. K.; Welf, E. S.; Weems, A. D.; Sapoznik, E.; Zhou, F.; Murali, V. S.; Garcia-Arcos, J. M.; Roh-Johnson, M.; Piel, M.; Dean, K. M.; Fiolka, R. P.; Danuser, G.
10.1101/2020.11.09.372912 — cell biology — Posted on 2022-11-08
2895 Live Imaging of Cutaneous Wound Healing in Zebrafish
Greenspan, L. J.; Ameyaw, K.; Castranova, D.; Mertus, C.; Weinstein, B. M.
10.1101/2022.11.07.515499 — cell biology — Posted on 2022-11-08
2900 Excitation creates a distributed pattern of cortical suppression due to varied recurrent input
O'Rawe, J. F.; Zhou, Z.; Li, A. J.; LaFosse, P. K.; Goldbach, H. C.; Histed, M. H.
10.1101/2022.08.31.505844 — neuroscience — Posted on 2022-11-08
2902 Integrative single-cell characterization of hypothalamus sex-differential and obesity-associated genes and regulatory elements
Nguyen, H. P.; Chan, C. S.; Cintron, D. L.; Sheng, R.; Harshman, L.; Nobuhara, M.; Ushiki, A.; Biellak, C.; An, K.; Gordon, G. M.; Mifsud, F.; Blake, A.; Huang, E. J.; Hemberg, M.; Vaisse, C.; Ahituv, N.
10.1101/2022.11.06.515311 — neuroscience — Posted on 2022-11-08
2903 Anatomically-based skeleton kinetics and pose estimation in freely-moving rodents
Monsees, A.; Voit, K.-M.; Wallace, D. J.; Sawinski, J.; Leks, E.; Scheffler, K.; Macke, J. H.; Kerr, J. N.
10.1101/2021.11.03.466906 — neuroscience — Posted on 2022-11-08
2906 Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities
Roider, T.; Baertsch, M. A.; Fitzgerald, D.; Voehringer, H.; Brinkmann, B. J.; Czernilofsky, F.; Knoll, M.; Llao-Cid, L.; Bruch, P.-M.; Liebers, N.; Schuerch, C. M.; Passerini, V.; Brobeil, A.; Mechtersheimer, G.; Mueller-Tidow, C.; Weigert, O.; Seiffert, M.; Nolan, G. P.; Huber, W.; Dietrich, S.
10.1101/2022.11.04.514366 — cancer biology — Posted on 2022-11-08
2907 The Circadian Clock is Disrupted in Pancreatic Cancer
Schwartz, P. B.; Nukaya, M.; Berres, M.; Rubinstein, C. D.; Wu, G.; Hogenesch, J.; Bradfield, C.; Ronnekleiv-Kelly, S.
10.1101/2022.11.01.514735 — cancer biology — Posted on 2022-11-08
2908 The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
Johannessen, J. A.; Formica, M.; Brathen, N. R.; Al Outa, A.; Aarsund, M.; Therrien, M.; Enserink, J. M.; Knaevelsrud, H.
10.1101/2022.11.08.515565 — cancer biology — Posted on 2022-11-08
2911 Identification of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia
Guhathakurta, P.; Rebbeck, R. T.; Denha, S. A.; Keller, A. R.; Carter, A. L.; Atang, A. E.; Svensson, B.; Thomas, D. D.; Hays, T. S.; Avery, A. W.
10.1101/2022.11.08.515660 — biophysics — Posted on 2022-11-08
2912 RAD-TGTs: Measurement of cellular tensions via flow cytometry and DNA sequencing enabled by force-dependent rupture and delivery of DNA tension probes
Pawlak, M. R.; Smiley, A. T.; Kelly, M. D.; Shamsan, G. A.; Anderson, S. M.; Smeester, B. A.; Largaespada, D. A.; Odde, D. J.; Gordon, W. R.
10.1101/2022.11.08.515662 — biophysics — Posted on 2022-11-08
2913 Single Photon smFRET. I. Theory and Conceptual Basis
Saurabh, A.; Fazel, M.; Safar, M.; Sgouralis, I.; Presse, S.
10.1101/2022.07.20.500887 — biophysics — Posted on 2022-11-08
2917 Increasing information gain in animal research by improving statistical model accuracy
Waterkamp, C.; von Kortzfleisch, V. T.; Neu, C.; Kitanovski, S.; Richter, S. H.; Hoffmann, D.
10.1101/2022.06.03.494726 — bioinformatics — Posted on 2022-11-08
2920 What drives chorismate mutase to top performance? Insights from a combined in silico and in vitro study
Thorbjornsrud, H. V.; Bressan, L.; Khatanbaatar, T.; Carrer, M.; Wuerth-Roderer, K.; Cordara, G.; Kast, P.; Cascella, M.; Krengel, U.
10.1101/2022.11.08.515563 — biochemistry — Posted on 2022-11-08
2923 The genome of the brackish-water malaria vector Anopheles aquasalis
Sepulveda, C. C. P.; Alencar, R. M.; Martinez-Villegas, L. E.; Bahia, A. C.; Santana, R. A.; Souza, I. B.; D'Elia, G. M. A.; Duarte, A. P. M.; Lacerda, M. V. G.; Monteiro, W. M.; Secundino, N. F. C.; Koerich, L. B.; Pimenta, P. F. P.
10.1101/2022.11.08.515629 — genomics — Posted on 2022-11-08
2927 High-resolution promoter interaction analysis in Type 3 Innate Lymphoid Cells implicates Batten Disease gene CLN3 in Crohn's Disease aetiology
Malysheva, V.; Ray-Jones, H.; Cazares, T. A.; Clay, O.; Ohayon, D.; Artemov, P.; Wayman, J. A.; Della Rosa, M.; Petitjean, C.; Booth, C.; Ellaway, J. I. J.; Orchard, W.; Chen, X.; Parameswaran, S.; Nagano, T.; Fraser, P.; Schoenfelder, S.; Weirauch, M.; Kottyan, L. C.; Smith, D. F.; Powell, N.; Weimer, J.; Wallace, C.; Miraldi, E. R.; Waggoner, S.; Spivakov, M.
10.1101/2022.10.19.512842 — genetics — Posted on 2022-11-08
2931 Nucleosome sensitivity distinguishes colon polyps based on their transformation status
Khadem, M.; Kossick, K.; Fedyshyn, Y.; Boardman, L.; Dennis, J. H.; Druliner, B.
10.1101/2022.11.08.515478 — molecular biology — Posted on 2022-11-08
2932 Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies
Molitor, L.; Klostermann, M.; Bacher, S.; Merl-Pham, J.; Spranger, N.; Burczyk, S.; Ketteler, C.; Rusha, E.; Tews, D.; Pertek, A.; Proske, M.; Busch, A.; Reschke, S.; Feederle, R.; Hauck, S. M.; Blum, H.; Drukker, M.; Fischer-Posovszky, P.; Koenig, J.; Zarnack, K.; Niessing, D.
10.1101/2022.02.09.479353 — molecular biology — Posted on 2022-11-08
2933 Human Nucleolar Protein 7 (NOL7) is required for pre-rRNA transcription and pre-18S rRNA processing
McCool, M. A.; Bryant, C. J.; Huang, H.; Ogawa, L. M.; Farley-Barnes, K. I.; Sondalle, S. B.; Abriola, L.; Surovtseva, Y. V.; Baserga, S. J.
10.1101/2022.11.08.515626 — molecular biology — Posted on 2022-11-08
2934 Fasciola hepatica juveniles interact with the host fibrinolytic system as a potential early-stage invasion mechanism
Serrat, J.; Becerro-Recio, D.; Torres-Valle, M.; Simon, F.; Valero, M. A.; Bargues, M. D.; Mas-Coma, S.; Siles-Lucas, M.; Gonzalez-Miguel, J.
10.1101/2022.11.07.515559 — molecular biology — Posted on 2022-11-08
2935 ToDD: Topological Compound Fingerprinting in Computer-Aided Drug Discovery
Demir, A.; Coskunuzer, B.; Segovia-Dominguez, I.; Chen, Y.; Gel, Y.; Kiziltan, B.
10.1101/2022.11.08.515685 — molecular biology — Posted on 2022-11-08
2936 On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur thanks to the previously uncharacterized homocysteine synthase Yll058w
Van Oss, S. B.; Parikh, S. B.; Coelho, N. C.; Wacholder, A.; Belashov, I.; Zdancewicz, S.; Michaca, M.; Xu, J.; Kang, Y. P.; Ward, N. P.; Yoon, S. J.; McCourt, K. M.; McKee, J.; Ideker, T.; VanDemark, A. P.; DeNicola, G. M.; Carvunis, A.-R.
10.1101/2022.01.19.476918 — molecular biology — Posted on 2022-11-08
2939 Application of Quasimetagenomics Methods to Define Microbial Diversity and Subtype Listeria monocytogenes in Dairy and Seafood Production Facilities
Kocurek, B. J.; Ramachandran, P.; Grim, C. J.; Morin, P.; Howard, L.; Ottesen, A.; Timme, R. E.; Leonard, S. R.; Rand, H.; Strain, E. A.; Tadesse, D. A.; Pettengill, J.; Lacher, D. W.; Mammel, M. K.; Jarvis, K. G.
10.1101/2022.11.07.515551 — microbiology — Posted on 2022-11-08
2940 Shigella serotypes associated with carriage in humans establish persistent infection in zebrafish
Torraca, V.; Brokatzky, D.; Miles, S. L.; Chong, C. E.; De Silva, P. M.; Baker, S.; Jenkins, C.; Holt, K. E.; Baker, K. S.; Mostowy, S.
10.1101/2022.11.08.515620 — microbiology — Posted on 2022-11-08
2941 Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system
Blanc, M.; Lettl, C.; Guerin, J.; Vieille, A.; Furler, S.; Briand-Schumacher, S.; Dreier, B.; Berge, C.; Pluckthun, A.; Vadon-Le Goff, S.; Fronzes, R.; Rousselle, P.; Fischer, W.; TERRADOT, L.
10.1101/2022.11.08.515452 — microbiology — Posted on 2022-11-08
2943 Ex vivo intestinal permeability assay (X-IPA) for tracking barrier function dynamics
Bootz-Maoz, H.; Simon, A.; Del Mare-Roumani, S.; Bennet, Y.; Zheng, D.; Amidror, S.; Elinav, E.; Yissachar, N.
10.1101/2022.11.08.515584 — microbiology — Posted on 2022-11-08
2944 Membrane-remodeling protein ESCRT-III homologs incarnate the evolution and morphogenesis of multicellular magnetotactic bacteria
Zhang, W.; Chen, J.; DAI, J.; Zhu, S.; Guenno, H. L.; Kosta, A.; Pan, H.; Qian, X.-X.; Santini, C. L.; Menguy, N.; Li, X.; Chen, Y.; Liu, J.; Cui, K.; Zhao, Y.; Liu, G.; Durand, E.; Zhang, W.-J.; Roussel, A.; Xiao, T.; Wu, L.-F.
10.1101/2022.11.08.515611 — microbiology — Posted on 2022-11-08
2945 Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by metastasis
Rahim, M. K.; Okholm, T. L. H.; Jones, K. B.; McCarthy, E. E.; Liu, C. C.; Yee, J. L.; Tamaki, S. J.; Marquez, D. M.; Tenvooren, I.; Wai, K.; Cheung, A.; Davidson, B. R.; Johri, V.; Samad, B.; O'Gorman, W. E.; Krummel, M. F.; Combes, A. J.; Angelo, M.; Fong, L.; Algazi, A. P.; Ha, P.; Spitzer, M. H.
10.1101/2022.11.08.513062 — immunology — Posted on 2022-11-08
2946 Activation-inducible CAR expression enables precise control over engineered CAR T cell function
Fraessle, S. P.; Tschulik, C.; Effenberger, M.; Cletiu, V.; Gerget, M.; Schober, K.; Busch, D. H.; Germeroth, L.; Stemberger, C.; Poltorak, M. P.
10.1101/2022.11.08.515608 — immunology — Posted on 2022-11-08
2947 Stabilizing brain-computer interfaces through alignment of latent dynamics
Karpowicz, B. M.; Ali, Y. H.; Wimalasena, L. N.; Sedler, A. R.; Keshtkaran, M. R.; Bodkin, K.; Ma, X.; Miller, L. E.; Pandarinath, C.
10.1101/2022.04.06.487388 — neuroscience — Posted on 2022-11-08
2948 Mechanisms underlying reshuffling of visual responses by optogenetic stimulation in mice and monkeys
Sanzeni, A.; Palmigiano, A.; Nguyen, T. H.; Luo, J.; Nassi, J. J.; Reynolds, J. H.; Histed, M. H.; Miller, K. D.; Brunel, N.
10.1101/2022.07.13.499597 — neuroscience — Posted on 2022-11-08
2949 Route-dependent spatial engram tagging in mouse dentate gyrus
Wilmerding, L. K.; Kondratyev, I.; Ramirez, S.; Hasselmo, M. E.
10.1101/2022.06.20.496824 — neuroscience — Posted on 2022-11-08
2950 Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later.
Attaheri, A.; Ni Choisdealbha, A.; Rocha, S.; Brusini, P.; Di Liberto, G. M.; Mead, N.; Olawole-Scott, H.; Boutris, P.; Gibbon, S.; Williams, I.; Grey, C.; Alfaro e Oliveira, M.; Brough, C.; Flanagan, S.; Goswami, U.
10.1101/2022.11.02.514963 — neuroscience — Posted on 2022-11-08
2951 Genomic and transcriptomic landscape of advanced renal cell cancer to individualize treatment strategy
de Joode, K.; van de Geer, W. S.; van Leenders, G. J. L. H.; Hamberg, P.; Westgeest, H. M.; Beeker, A.; Oosting, S. F.; van Rooijen, J. M.; Beerepoot, L. V.; Labots, M.; Mathijssen, R. H. J.; Lolkema, M. P.; Cuppen, E.; Sleijfer, S.; van de Werken, H. J. G.; van der Veldt, A. A. M.
10.1101/2022.04.22.488773 — cancer biology — Posted on 2022-11-08
2955 Enhanced stability of the SARS CoV-2 spike glycoprotein trimer following modification of an alanine cavity in the protein core.
Poumbourios, P.; Langer, C.; Boo, I.; Zakir, T.; Center, R. J.; Akerman, A.; Milogiannakis, V.; Aggarwal, A.; Turville, S. G.; Drummer, H. E.
10.1101/2022.11.08.515567 — microbiology — Posted on 2022-11-08
2956 Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection.
Milighetti, M.; Peng, Y.; Tan, C. C. S.; Mark, M.; Nageswaran, G.; Byrne, S.; Ronel, T.; Peacock, T.; Mayer, A.; Chandran, A.; Rosenheim, J.; Wheelan, M.; Yao, X.; Liu, G.; Felce, S. L.; Dong, T.; Mentzer, A. J.; Knight, J. C.; Balloux, F.; Greenstein, E.; Reich-Zeliger, S.; Pade, C.; Gibbons, J. M.; Semper, A.; Brooks, T.; Otter, A.; Altmann, D. M.; Boyton, R. J.; Maini, M. K.; McKnight, A.; Manisty, C.; Treibel, T. A.; Moon, J. C.; COVIDsortium Investigators, ; Noursadeghi, M.; Chain, B.
10.1101/2022.11.08.515436 — immunology — Posted on 2022-11-08
2958 mEnrich-seq: Methylation-guided enrichment sequencing of bacterial taxa of interest from microbiome
Cao, L.; Kong, Y.; Fan, Y.; Ni, M.; Tourancheau, A.; Ksiezarek, M.; Mead, E. A.; Koo, T.; Gitman, M. R.; Zhang, X.-S.; Fang, G.
10.1101/2022.11.07.515285 — genomics — Posted on 2022-11-08
2959 Kinesin family motors modify transcription mediated by ERR1 using a conserved nuclear receptor box motif
Seneviratne, P. B.; Lidagoster, S.; Valbuena-Castor, S.; Lashley, K.; Saha, S.; Kreitzer, G.
10.1101/2022.11.08.515201 — cell biology — Posted on 2022-11-08
2960 Microtubule binding-induced allostery promotes LIS1 dissociation from dynein prior to cargo transport
Ton, W. D.; Wang, Y.; Chai, P.; Beauchamp-Perez, C.; Flint, N. T.; Lammers, L. G.; Xiong, H.; Zhang, K.; Markus, S. M.
10.1101/2022.11.08.515461 — cell biology — Posted on 2022-11-08
2964 Lifelong temporal dynamics of the gut microbiome associated with longevity in mice
Takayasu, L.; Watanabe, E.; Umeyama, T.; Kurokawa, R.; Ogata, Y.; Kiguchi, Y.; Masuoka, H.; Umezaki, M.; Hattori, M.; Suda, W.
10.1101/2022.11.07.515511 — microbiology — Posted on 2022-11-08
2965 IL-33-induced neutrophilic inflammation and NETosis underlie rhinovirus-triggered exacerbations of asthma
Curren, B.; Ahmed, T.; Howard, D. R.; Ullah, A.; Sebina, I.; Rashid, R.; Sikder, A. A.; Bissell, A.; Ngo, S.; Jackson, D.; Toussaint, M.; Edwards, M.; Johnston, S.; McSorley, H. J.; Phipps, S.
10.1101/2022.11.07.515526 — immunology — Posted on 2022-11-08
2967 Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2
Lee, Y.; Yeo, I. S.; Kim, N.; Lee, D.-K.; Kim, K.-T.; Yoon, J.; Hong, Y. B.; Choi, B.-O.; Kosodo, Y.; Kim, D.; Park, J.; Song, M.-R.
10.1101/2022.11.07.515417 — neuroscience — Posted on 2022-11-08
2969 A F420-dependent single domain chemogenetic tool for protein de-dimerization
Antoney, J.; Kainrath, S.; Ahmed, F. H.; Kang, S. W.; Mackie, E. R. R.; Soares da Costa, T. P.; Jackson, C. J.; Janovjak, H.
10.1101/2022.11.07.515376 — synthetic biology — Posted on 2022-11-08
2975 scAN10: A reproducible and standardized pipeline for processing 10X single cell RNAseq data
Lepetit, M.; Ilie, M. D.; Chanal, M.; Raverot, G.; Bertolino, P.; Picard, F.; Gandrillon, O.
10.1101/2022.11.07.515546 — bioinformatics — Posted on 2022-11-08
2978 A Scalable and Adaptive Ultra-high-density Fan-out Strategy for High-throughput Flexible Microelectrodes
Zhang, H.; Wang, Y.; Yang, X.; Yuan, M.; Yang, X.; Gui, Q.; Wang, Y.; Chen, H.; Liu, R.; Pei, W.
10.1101/2022.11.07.515530 — bioengineering — Posted on 2022-11-08
2980 A more complete story of the genetic bases of resistance to the rice hoja blanca disease
Silva, A.; Montoya, M. E.; Quintero, C.; Cuasquer, J.; Tohme, J.; Graterol, E.; Cruz, M.; Lorieux, M.
10.1101/2022.11.07.515427 — genetics — Posted on 2022-11-08
2984 Out of thin air: surveying tropical bat roosts through air sampling of eDNA
Garrett, N. R.; Watkins, J.; Francis, C.; Simmons, N. B.; Ivanova, N. V.; Naaum, A.; Briscoe, A.; Drinkwater, R.; Clare, E. L.
10.1101/2022.11.07.515479 — ecology — Posted on 2022-11-08
2985 Live Imaging of Cutaneous Wound Healing in Zebrafish
Weinstein, B. M.; Greenspan, L. J.; Ameyaw, K.; Castranova, D.; Mertus, C.
10.1101/2022.11.07.515499 — cell biology — Posted on 2022-11-08
2988 Bursting Translation on Single mRNAs in Live Cells
Livingston, N. M.; Kwon, J.; Valera, O.; Saba, J. A.; Sinha, N. K.; Reddy, P.; Nelson, B.; Wolfe, C.; Ha, T.; Green, R.; Liu, J.; Wu, B.
10.1101/2022.11.07.515520 — molecular biology — Posted on 2022-11-08
2994 Tracing the development and lifespan change of population-level structural asymmetry in the cerebral cortex
Roe, J. M.; Vidal-Pineiro, D.; Amlien, I. K.; Pan, M.; Sneve, M. H.; Thiebaut de Schotten, M.; Friedrich, P.; Sha, Z.; Francks, C.; Wang, Y.; Walhovd, K. B.; Fjell, A. M.; Westerhausen, R.
10.1101/2021.11.25.469988 — neuroscience — Posted on 2022-11-08
2996 Exploiting Embryonic Niche Conditions to Grow Wilms Tumor Blastema in Culture
Wojcik, H.; Lovvorn, H. N.; Hollingshead, M.; Pierce, J.; Stotler, H.; Murphy, A. J.; Borgel, S.; Phelps, H. M.; Correa, H.; Perantoni, A. O.
10.1101/2022.11.07.515473 — cancer biology — Posted on 2022-11-08
2998 GIL: A Python package for designing custom indexing primers
Mateyko, N.; Tariq, O.; Chen, X. E.; Cheney, W.; Salaudeen, A. L.; Luthra, I.; Nikpour, N.; Rafi, A. M.; Kamali Deghan, H.; Jensen, C.; de Boer, C.
10.1101/2022.11.04.514296 — bioinformatics — Posted on 2022-11-08
3002 Time to first cigarette and its impact on lung tumorigenesis
Zhang, T.; Sang, J.; Caporaso, N.; Gu, F.; Hutchinson, A.; Consonni, D.; Pesatori, A. C.; Homer, R.; Chanock, S.; Landi, M. T.
10.1101/2022.11.07.515434 — genomics — Posted on 2022-11-08
3003 Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing
Auer, P. L.; Jakubek, Y. A.; Zhou, Y.; Stilp, A. M.; Bacon, J.; Wong, J.; Mitchell, B.; Lewis, J.; Boerwinkle, E.; Loos, R. J. F.; Preuss, M.; Barnes, K.; Pankratz, N.; Fornage, M.; Redline, S.; Psaty, B. M.; Bis, J. C.; Silverman, E.; Cho, M.; Yun, J.; Ramachandran, V.; Mathias, R. A.; Taub, M.; Peyser, P. A.; Smith, J. A.; Kardia, S.; Arnett, D.; North, K. E.; Raffield, L. M.; Carson, A.; Doyle, M.; Rich, S.; Rotter, J.; Guo, X.; Cox, N.; Mack, T.; Chasman, D.; Machiela, M.; Ozcan, Z.; Conomos, M.; Li, Y.; Desai, P.; Bick, A.; Reiner, A. P.; Scheet, P.
10.1101/2022.11.07.515222 — genomics — Posted on 2022-11-08
3004 Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex
Fujita, M.; Gao, Z.; Zeng, L.; McCabe, C.; White, C. C.; Ng, B.; Green, G. S.; Rozenblatt-Rosen, O.; Phillips, D.; Amir-Zilberstein, L.; Lee, H.; Pearse, R. V.; Khan, A.; Vardarajan, B. N.; Kiryluk, K.; Ye, C. J.; Klein, H.-U.; Wang, G.; Regev, A.; Habib, N.; Schneider, J. A.; Wang, Y.; Young-Pearse, T.; Mostafavi, S.; Bennett, D. A.; Menon, V.; De Jager, P. L.
10.1101/2022.11.07.515446 — genomics — Posted on 2022-11-08
3005 High Coverage Mitogenomes and Y-Chromosomal Typing Reveal Ancient Lineages in the Modern-day Szekely Population in Romania
Borbely, N.; Szekely, O.; Szeifert, B.; Gerber, D.; Mathe, I.; Benko, E.; Mende, B. G.; Egyed, B.; Pamjav, H.; Szecsenyi-Nagy, A.
10.1101/2022.11.07.515481 — genetics — Posted on 2022-11-08
3008 Urban ecological connectivity as a planning tool for different animal species.
Kirk, H.; Soanes, K.; Amati, M.; Bekessy, S.; Harrison, L.; Parris, K.; Ramalho, C.; van der Ree, R.; Threlfall, C.
10.1101/2022.11.06.515356 — ecology — Posted on 2022-11-08
3009 A phenomic modeling approach for using chlorophyll-a fluorescence-based measurements on coral photosymbionts: a step towards bio-optical bleaching prediction
Hoadley, K.; Lockridge, G.; McQuagge, A.; Pahl, K. B.; Lowry, S.; Wong, S.; Craig, Z.; Petrik, C.; Klepac, C.; Muller, E.
10.1101/2022.11.07.515332 — ecology — Posted on 2022-11-08
3010 A gene essentiality signature for studying the mechanism of action of drugs
Wang, W.; Bao, J.; Zheng, S.; Huang, S.; Aldahdooh, J.; Wang, Y.; Eriksson, J. T.; Tanoli, Z.; Tang, J.
10.1101/2022.11.07.514541 — systems biology — Posted on 2022-11-08
3011 Single Photon smFRET. I. Theory and Conceptual Basis
Saurabh, A.; Fazel, M.; Safar, M.; Sgouralis, I.; Presse, S.
10.1101/2022.07.20.500887 — biophysics — Posted on 2022-11-08
3012 Single Photon smFRET. III. Application to Pulsed Illumination
Safar, M.; Saurabh, A.; Sarkar, B.; Fazel, M.; Ishii, K.; Tahara, T.; Sgouralis, I.; Presse, S.
10.1101/2022.07.20.500892 — biophysics — Posted on 2022-11-08
3016 A personal, reference quality, fully annotated genome from a Saudi individual
Kulmanov, M.; Tawfiq, R.; Al Ali, H.; Abdelhakim, M.; Alarawi, M.; Aldakhil, H.; Alhattab, D.; Alsolme, E.; Althagafi, A.; Angelov, A.; Bougouffa, S.; Driguez, P.; Liu, Y.; Park, C.; Putra, A.; Reyes-Ramos, A. M.; Hauser, C. A. E.; Cheung, M. S.; Abedalthagafi, M. S.; Hoehndorf, R.
10.1101/2022.11.05.515129 — bioinformatics — Posted on 2022-11-08
3017 Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits
Akle, S.; Chun, S.; Teodosiadis, A.; Cade, B. E.; Wang, H.; Sofer, T.; Evans, D. S.; Stone, K. L.; Gharib, S. A.; Mukherjee, S.; Palmer, L. J.; Hillman, D.; Rotter, J. I.; Stamatoyannopoulos, J. A.; Redline, S.; Cotsapas, C.; Sunyaev, S. R.
10.1101/832162 — genetics — Posted on 2022-11-08
3019 Multi-Layered Maps of Neuropil with Segmentation-Guided Contrastive Learning
Dorkenwald, S.; Li, P.; Januszewski, M.; Berger, D. R.; Maitin-Shepard, J.; Bodor, A. L.; Collman, F.; Schneider-Mizell, C. M.; Macarico da Costa, N.; Lichtman, J. W.; Jain, V.
10.1101/2022.03.29.486320 — neuroscience — Posted on 2022-11-08
3020 High-sensitivity vision restoration via ectopic expression of chimeric rhodopsin in mice
Katada, Y.; Yoshida, K.; Serizawa, N.; Kobayashi, K.; Negishi, K.; Hideyuki, O.; Kandori, H.; Tsubota, K.; Kurihara, T.
10.1101/2020.09.17.301523 — neuroscience — Posted on 2022-11-08
3022 Comparative analysis of single-cell and single-nucleus RNA-sequencing in a rabbit model of retinal detachment-related proliferative vitreoretinopathy.
Santiago, C. P.; Gimmen, M. Y.; Lu, Y.; McNally, M. M.; Duncan, L. H.; Creamer, T.; Orzolek, L.; Blackshaw, S.; Singh, M.
10.1101/2022.11.07.515504 — neuroscience — Posted on 2022-11-08
3026 Functional and structural asymmetry suggest a unifying principle for catalysis in integral membrane-bound pyrophosphatases
Strauss, J.; Wilkinsion, C.; Vidilaseris, K.; Ribeiro, O.; Liu, J.; Hillier, J.; Malinen, A.; Gehl, B.; Jeuken, L.; Pearson, A.; Goldman, A.
10.1101/2022.11.07.515396 — biochemistry — Posted on 2022-11-07
3027 Genomic Structural Equation Modeling Reveals Latent Phenotypes in the Human Cortex with Distinct Genetic Architecture
Morey, R. A.; Zheng, Y.; Sun, D.; Garrett, M. E.; Gasperi, M.; Maihofer, A. X.; Baird, L.; Grasby, K.; Huggins, A.; Haswell, C. C.; Thompson, C. P. M.; Medland, S.; Gustavson, D. E.; Panizzon, M. S.; Kremen, W. S.; Nievergelt, C. M.; Ashley-Koch, A. E.; Logue, M. W.
10.1101/2022.11.04.515213 — genomics — Posted on 2022-11-08
3029 The septate junction component Bark beetle is required for Drosophila intestinal barrier function and homeostasis
Hodge, R.; Ghannam, M.; Edmond, E.; de la Torre, F.; D'Alterio, C.; Kaya, N. H.; Resnik-Docampo, M.; Reiff, T.; Jones, D. L.
10.1101/2022.11.07.515432 — cell biology — Posted on 2022-11-07
3030 A rapid platform for 3D patient-derived cutaneous neurofibroma organoid establishment and screening
Nguyen, H. T. L.; Kohl, E.; Bade, J.; Eng, S. E.; Tosevska, A.; Al Shihabi, A.; Hong, J. J.; Dry, S.; Boutros, P. C.; Panossian, A.; Gosline, S. J.; Soragni, A.
10.1101/2022.11.07.515469 — systems biology — Posted on 2022-11-07
3032 Incoherent merger network for robust ratiometricgene expression response
Kwon, U.; Huang, H.-H.; Chavez, J. L.; Harbaugh, K.; Harbaugh, S.; del Vecchio, D.
10.1101/2022.11.07.515449 — synthetic biology — Posted on 2022-11-07
3034 dATP Elevation Induces Myocardial Metabolic Remodeling to Support Improved Cardiac Function
Mhatre, K. N.; Murray, J. D.; Flint, G.; McMillen, T. S.; Weber, G.; Shakeri, M.; Tu, A.-Y.; Steczina, S.; Weiss, R. S.; Marcinek, D.; Murry, C. E.; Raftery, D.; Tian, R.; Moussavi-Harami, F.; Regnier, M.
10.1101/2022.11.07.515235 — physiology — Posted on 2022-11-07
3035 A Peptide Triple Agonist of GLP-1, Neuropeptide Y1, and Neuropeptide Y2 Receptors Promotes Glycemic Control and Weight Loss
Chichura, K. S.; Elfers, C. T.; Salameh, T.; Kamat, V.; Chepurny, O. G.; McGivney, A.; Milliken, B. T.; Holz, G. G.; Appleby, S. V.; Hayes, M. R.; Sweet, I. R.; Roth, C. L.; Doyle, R. P.
10.1101/2022.11.07.515458 — pharmacology and toxicology — Posted on 2022-11-07
3039 DNA-caged Nanoparticles via Electrostatic Self-Assembly
Jergens, E.; de Araujo Fernandes-Junior, S.; Cui, Y.; Robbins, A.; Castro, C.; Poirier, M. G.; Gurcan, M. N.; Otero, J. J.; Winter, J. O.
10.1101/2022.11.07.515456 — bioengineering — Posted on 2022-11-07
3040 Human cerebrospinal fluid sample preparation and annotation for integrated lipidomics and metabolomics profiling studies
Hooshmand, K.; Xu, J.; Simonsen, A. H.; Wretlind, A.; Zawadzki, A. d.; Sulek, K.; Hasselbalch, S. G.; Legido-quigley, C.
10.1101/2022.11.07.515425 — biochemistry — Posted on 2022-11-07
3043 Unearthing modes of climatic adaptation in underground storage organs across Liliales
Tribble, C. M.; May, M. R.; Jackson-Gain, A.; Zenil-Ferguson, R.; Specht, C. D.; Rothfels, C. J.
10.1101/2021.09.03.458928 — evolutionary biology — Posted on 2022-11-07
3044 Kelpwatch: A new visualization and analysis tool to explore kelp canopy dynamics reveals variable response to and recovery from marine heatwaves
Bell, T.; Cavanaugh, K. C.; Saccomanno, V. R.; Cavanaugh, K. C.; Houskeeper, H. F.; Eddy, N.; Schuetzenmeister, F.; Rindlaub, N.; Gleason, M.
10.1101/2022.07.04.498739 — ecology — Posted on 2022-11-07
3046 Rules for hardening influenza A virus liquid condensates
Etibor, T. A.; Vale-Costa, S.; Sridharan, S.; Bras, D.; Becher, I.; Mello, V. H.; Ferreira, F.; Alenquer, M.; Savitski, M. M.; Amorim, M. J.
10.1101/2022.08.03.502602 — cell biology — Posted on 2022-11-07
3047 Spatiotemporal coordination of stem cell behavior following alveolar injury
Chioccioli, M.; Magruder, S.; McDonough, J. E.; Nouws, J.; Gonzalez, D.; Borriello, L.; Traub, B.; Ye, X.; Hendry, C. E.; Entenberg, D.; Krishnaswamy, S.; Kaminski, N.; Sauler, M.
10.1101/2022.10.28.514255 — cell biology — Posted on 2022-11-07
3051 Comparison of HAV and HCV infections in vivo and in vitro reveals distinct patterns of innate immune evasion and activation
Colasanti, O.; Burm, R.; Huang, H.-E.; Riedl, T.; Traut, J.; Gillich, N.; Li, T.-F.; Corneillie, L.; Faure-Dupuy, S.; Gruenvogel, O.; Heide, D.; Lee, J.-Y.; Tran, C. S.; Merle, U.; Chironna, M.; Florian, V. W.; Esser-Nobis, K.; Binder, M.; Bartenschlager, R.; Heikenwaelder, M.; Meuleman, P.; Lohmann, V.
10.1101/2022.11.07.515428 — immunology — Posted on 2022-11-07
3053 Engineering circuits of human iPSC-derived neurons and rat primary glia
Girardin, S.; Ihle, S. J.; Menghini, A.; Krubner, M.; Tognola, L.; Duru, J.; Ruff, T.; Fruh, I.; Muller, M.; Vörös, J.
10.1101/2022.11.07.515431 — neuroscience — Posted on 2022-11-07
3056 Growth hormone receptor (GHR) in AgRP neurons regulatesthermogenesis in aged mice in a sex-specific manner
Stilgenbauer, L.; de Lima, J. B. M.; Debarba, L. K.; Khan, M.; Koshko, L.; Kopchick, J. J.; Bartke, A.; Schneider, A.; Sadagurski, M.
10.1101/2022.08.31.506031 — neuroscience — Posted on 2022-11-07
3059 Protective role of podocytic IL-15/STAT5 pathway in experimental focal and segmental glomerulosclerosis
Niasse, A.; Louis, K.; Lenoir, O.; Schwarz, C.; Xu, X.; Couturier, A.; DOBOSZIEWICZ, H.; Corchia, A.; Placier, S.; Vandermeersch, S.; Hennighausen, L.; Frere, P.; Galichon, P.; Surin, B.; Ouchelouche, S.; Louedec, L.; Migeon, T.; Verpont, M.-C.; Buob, D.; Dubois-Xu, Y.-C.; Francois, H.; Rondeau, E.; Mesnard, L.; Hadchouel, J.; Luque, Y.
10.1101/2022.11.07.515420 — pathology — Posted on 2022-11-07
3060 Identification of functional immune and neuronal tumor cells in glioma
Curry, R. N.; McDonald, M. F.; Ma, Q.; Meyer, J.; Aiba, I.; Lozzi, B.; Cervantes, A.; Ko, Y.; Luna-Figuera, E.; Choi, D.-J.; Lee, Z.-F.; Jing, J.; Harmanci, A. O.; Rosenbaum, A.; He, P.; Mohila, C.; Jalali, A.; Noebels, J.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2022.11.05.515316 — cancer biology — Posted on 2022-11-07
3063 Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities
Roider, T.; Baertsch, M. A.; Fitzgerald, D.; Voehringer, H.; Brinkmann, B. J.; Czernilofsky, F.; Knoll, M.; Llao-Cid, L.; Bruch, P.-M.; Liebers, N.; Schuerch, C. M.; Passerini, V.; Brobeil, A.; Mueller-Tidow, C.; Weigert, O.; Seiffert, M.; Nolan, G. P.; Huber, W.; Dietrich, S.
10.1101/2022.11.04.514366 — cancer biology — Posted on 2022-11-07
3064 Allosteric activation of cell wall synthesis during bacterial growth
Shlosman, I.; Fivenson, E.; Gilman, M.; Sisley, T.; Walker, S.; Bernhardt, T. G.; Kruse, A. C.; Loparo, J. J.
10.1101/2022.11.07.515454 — biophysics — Posted on 2022-11-07
3067 Folding stabilities of ribosome-bound nascent polypeptides probed by mass spectrometry
Tan, R.; Hoare, M.; Welle, K. A.; Swovick, K.; Hryhorenko, J. R.; Ghaemmaghami, S.
10.1101/2022.11.07.515500 — biochemistry — Posted on 2022-11-07
3068 Goldilocks calcium and the mitochondrial respiratory chain: too much, too little, just right
Vilas-Boas, E. A.; Cabral-Costa, J. V.; Ramos, V. M.; Caldeira da Silva, C. C.; Kowaltowski, A. J.
10.1101/2022.04.12.488015 — biochemistry — Posted on 2022-11-07
3069 Development of a high-throughput starch digestibility assay reveals wide variation among the A. E. Watkins wheat landrace collection
Zafeiriou, P.; Savva, G. M.; Ahn-Jarvis, J. H.; Warren, F. J.; Pasquariello, M.; Griffiths, S.; Seung, D.; Hazard, B. A.
10.1101/2022.11.04.515016 — biochemistry — Posted on 2022-11-07
3071 Whole-body gene expression atlas of an adult metazoan
Ghaddar, A.; Armingol, E.; Huynh, C.; Gevirtzman, L.; Lewis, N. E.; Waterston, R.; O'Rourke, E.
10.1101/2022.11.06.515345 — genomics — Posted on 2022-11-07
3076 GDF3 simultaneously antagonizes BMP signaling and activates TGFβ receptor signaling
Ramachandran, D.; Kotikalapudi, N.; Maridas, D. E.; Gulko, A.; Tsai, L. T.; Rosen, V.; Banks, A. S.
10.1101/2022.11.07.515236 — cell biology — Posted on 2022-11-07
3078 4-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses
Lieber, C. M.; Aggarwal, M.; Yoon, J.-J.; Cox, R.; Sourimant, J.; Toots, M.; Kang, H.-J.; Johnson, S. K.; Jones, C. A.; Sticher, Z. M.; Kolykhalov, A.; Sindaine, M. T.; Tompkins, S. M.; Planz, O.; Painter, G. R.; Natchus, M. G.; Sakamoto, K.; Plemper, R. K.
10.1101/2022.11.05.515296 — microbiology — Posted on 2022-11-07
3079 Landscape-scale exposure to multiazole-resistant Aspergillus fumigatus bioaerosols
Shelton, J. M. G.; Rhodes, J.; Uzzell, C. B.; Hemmings, S.; Brackin, A. P.; Sewell, T. R.; Alghamdi, A.; Dyer, P. S.; Fraser, M.; Borman, A. M.; Johnson, E. M.; Piel, F. B.; Singer, A. C.; Fisher, M.
10.1101/2022.11.07.515445 — microbiology — Posted on 2022-11-07
3081 Adenovirus type 34 and HVR1-deleted Adenovirus type 5 do not bind to PF4: clearing the path towards vectors without thrombosis risk
Sallard, E.; Pembaur, D.; Schroeer, K.; Schellhorn, S.; Koukou, G.; Schmidt, N.; Zhang, W.; Kreppel, F.; Ehrhardt, A.
10.1101/2022.11.07.515483 — microbiology — Posted on 2022-11-07
3083 Multilevel human secondary lymphoid immune system compartmentalization revealed by complementary multiplexing and mass spectrometry imaging approaches
Oyler, B. L.; Valencia-Davila, J. A.; Moysi, E.; Molyvdas, A.; Ioannidou, K.; March, K.; Ambrozak, D.; DeLeval, L.; Fabozzi, G.; Woods, A. S.; Koup, R. A.; Petrovas, C.
10.1101/2022.11.01.514691 — immunology — Posted on 2022-11-07
3084 Heavy-chain CDR3-engineered B cells facilitate in vivo evaluation of HIV-1 vaccine candidates
He, W.; Ou, T.; Skamangas, N.; Bailey, C.; Bronkema, N.; Guo, Y.; Yin, Y.; Kobzarenko, V.; Zhang, X.; Pan, A.; Liu, X.; Allwardt, A.; Mitra, D.; Quinlan, B.; Sanders, R.; Choe, H.; Farzan, M.
10.1101/2022.11.07.515497 — immunology — Posted on 2022-11-07
3085 Continuous automated MRS data analysis workflow for applied studies
Zoellner, H. J.; Davies-Jenkins, C. W.; Lee, E. G.; Hendrickson, T. J.; Edden, R. A.; Gudmundson, A. T.; Oeltzschner, G.
10.1101/2022.11.03.515056 — neuroscience — Posted on 2022-11-07
3086 Periodic neglect after frontoparietal lesions provides causal evidence for rhythmic attention sampling
Raposo, I.; Szczepanski, S.; Haaland, K.; Endestad, T.; Solbakk, A.-K.; Knight, R. T.; Helfrich, R. F.
10.1101/2022.11.07.515418 — neuroscience — Posted on 2022-11-07
3090 Bias in group-level EEG microstate analysis
Murphy, M.; Wang, J.; Jiang, C.; Wang, L.; Kozhemiako, N.; Wang, Y.; GRINS Consortium, ; Pan, J. Q.; Purcell, S. M.
10.1101/2022.11.07.515464 — neuroscience — Posted on 2022-11-07
3091 Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills
Vassiliadis, P.; Beanato, E.; Popa, T.; Windel, F.; Morishita, T.; Neufeld, E.; Duque, J.; Derosiere, G.; Wessel, M. J.; Hummel, F. C.
10.1101/2022.11.07.515477 — neuroscience — Posted on 2022-11-07
3093 DNA origami directed virus capsid polymorphism
Seitz, I.; Kumpula, E.-P.; Anaya-Plaza, E.; Cornelissen, J. J.; Linko, V.; Huiskonen, J. T.; Kostiainen, M. A.
10.1101/2022.11.07.515152 — bioengineering — Posted on 2022-11-07
3094 ARF6 is a host factor for SARS-CoV-2 infection in vitro
Mirabelli, C.; Sherman, E. J.; Bragazzi Cunha, J.; Wotring, J. W.; El Saghir, J.; Harder, J.; Sexton, J. Z.; Emmer, B. T.; Wobus, C. E.
10.1101/2022.06.09.495482 — microbiology — Posted on 2022-11-07
3097 The soil microbiome reduces Striga infection of sorghum by modulation of host-derived signaling molecules and root development
Kawa, D.; Thiombiano, B.; Shimels, M.; Taylor, T.; Walmsley, A.; Vahldick, H. E.; Leite, M. F.; Musa, Z.; Bucksch, A.; Dini-Andreote, F.; Chen, A. J.; Daksa, J.; Etalo, D.; Tessema, T.; Kuramae, E. E.; Raaijmakers, J. M.; Bouwmeester, H.; Brady, S. M.
10.1101/2022.11.06.515382 — plant biology — Posted on 2022-11-07
3098 Temporal Vascular Endothelial Growth Factor Sub-type gene Switching in SARS-CoV Pathogenesis. Interpretation through in vivo Murine C57BL Models
Rashid, A.; Malik, Z. A.; Sharma, V.; Sharma, A.; Gupta, L.; Alkhazaimi, H.; Shaikh, G.; Al-Dubai, A.; Hussain, A.
10.1101/2022.11.06.515327 — immunology — Posted on 2022-11-07
3099 Novel inhibitors against COVID-19 main protease suppressed viral infection
Ramachandran, V.; Liu, Y.; He, Q.; Tang, A.; Ronaldson, P.; Schenten, D.; Chang, R.
10.1101/2022.11.05.515305 — pathology — Posted on 2022-11-07
3101 Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses
Jiang, B.; Schmitt, M. J.; Rand, U.; Company, C.; Grossmann, M.; Serresi, M.; Cicin-Sain, L.; Gargiulo, G.
10.1101/2022.11.05.515197 — bioengineering — Posted on 2022-11-07
3102 Wildlife exposure to SARS-CoV-2 across a human use gradient
Goldberg, A. R.; Langwig, K. E.; Marano, J. M.; Sharp, A. K.; Brown, K. L.; Ceci, A.; Kailing, M. J.; Briggs, R.; Roby, C.; Brown, A. M.; Weger-Lucarelli, J.; Finkielstein, C. v.; Hoyt, J. R.
10.1101/2022.11.04.515237 — ecology — Posted on 2022-11-07
3103 Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains
Yang, Y.; Zhang, W.; Murzin, A. G.; Schweighauser, M.; Huang, M.; Lovestam, S.; Peak-Chew, S. Y.; Saito, T.; Saido, T. C.; McDonald, J.; Lavenir, I.; Ghetti, B.; Graff, C.; Kumar, A.; Nordberg, A.; Goedert, M.; Scheres, S. H.
10.1101/2022.11.07.515410 — neuroscience — Posted on 2022-11-07
3106 Platelets supply p38 MAPK signaling that licenses pro-inflammatory cytokine responses of human monocytes
Hawwari, I.; Rosero, N.; Ribeiro, L. S.; Demczuk, A.; Teichmann, L. S.; Meffert, L.; Bertheloot, D.; Franklin, B. S.
10.1101/2022.08.10.503291 — immunology — Posted on 2022-11-07
3109 The Siglec-sialic acid-axis is a target for innate immunotherapy of glioblastoma
Schmassmann, P.; Roux, J.; Buck, A.; Tatari, N.; Hogan, S.; Wang, J.; Lee, S.; Snijder, B.; Martins, T. A.; Ritz, M.-F.; Shekarian, T.; Kaymak, D.; McDaid, M.; Weller, M.; Weiss, T.; Laubli, H.; Hutter, G.
10.1101/2022.11.07.515406 — cancer biology — Posted on 2022-11-07
3110 Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome
Dinstag, G.; Shulman, E. D.; Elis, E.; Ben-Zvi, D. S.; Tirosh, O.; Maimon, E.; Meilijson, I.; Elalouf, E.; Temkin, B.; Vitkovsky, P.; Schiff, E.; Hoang, D.-T.; Sinha, S.; Nair, N. U.; Sang Lee, J.; Schaffer, A. A.; Ronai, Z.; Juric, D.; Apolo, A. B.; Dahut, W. L.; Lipkowitz, S.; Berger, R.; Kurzrock, R.; Papanicolau-Sengos, A.; Karzai, F.; Gilbert, M. R.; Aldape, K.; Rajagopal, P. S.; Beker, T.; Ruppin, E.; Aharonov, R.
10.1101/2022.02.27.481627 — bioinformatics — Posted on 2022-11-07
3111 Human cerebrospinal fluid sample preparation and annotation for integrated lipidomics and metabolomics profiling studies
Hooshmand, K.; Xu, J.; Simonsen, A. H.; Wretlind, A.; Zawadzki, A. d.; Sulek, K.; Hasselbalch, S. G.; Legido-quigley, C.
10.1101/2022.11.07.515425 — biochemistry — Posted on 2022-11-07
3112 Structural Insights into Branch Site Proofreading by Human Spliceosome
Zhang, X.; Zhan, X.; Bian, T.; Yang, F.; Li, P.; Lu, Y.; Xing, Z.; Cliff Zhang, Q.; Shi, Y.
10.1101/2022.11.07.515429 — biochemistry — Posted on 2022-11-07
3117 DNA methylation regulates sex-biased gene expression in the house sparrow
Lundregan, S. L.; Makinen, H.; Viitaniemi, H.; Ronning, B.; Jensen, H.; Husby, A.
10.1101/2022.11.07.515394 — evolutionary biology — Posted on 2022-11-07
3121 A novel pathway of functional microRNA uptake and mitochondria delivery
Liu, J.; Li, W.; Li, J.; Song, E.; Liang, H.; Rong, W.; Jiang, X.; Xu, N.; Wang, W.; Qu, S.; Zhang, Y.; Zhang, C.-Y.; Zen, K.
10.1101/2022.11.07.515397 — cell biology — Posted on 2022-11-07
3126 Positive associations matter: microbial relationships drive tick microbiome composition
Fountain-Jones, N. M.; Khoo, B. S.; Rau, A.; Berman, J. D.; Burton, E. N.; Oliver, J. D.
10.1101/2022.11.06.515366 — microbiology — Posted on 2022-11-07
3127 Shigella ipaA mediates actin bundling through diffusible vinculin oligomers with activation imprint
Valencia-Gallardo, C. M.; Aguilar, D. I.; Khakzad, H.; Cocom-Chan, B.; Bou-Nader, C.; Velours, C.; Zarrouk, Y.; Le Clainche, C.; Malosse, C.; Borges-Lima, D.; Quenech'Du, N.; Mazhar, B.; Essid, S.; Fontecave, M.; Asnacios, A.; Chamot-Rooke, J.; Malmstrom, L.; Tran Van Nhieu, G.
10.1101/2022.11.07.515412 — microbiology — Posted on 2022-11-07
3131 Biomechanics of Finger Pad Response under Torsion
du Bois de Dunilac, S.; Cordova Bulens, D.; Lefevre, P.; Redmond, S. J.; Delhaye, B. P.
10.1101/2022.11.07.515186 — neuroscience — Posted on 2022-11-07
3132 Rescue of the increased susceptibility to Mild Chronic Oxidative Stress of iNeurons carrying the MAPT Chromosome 17q21.3 H1/H1 risk allele by FDA-approved compounds
Sadikoglou, E.; Domingo-Fernandez, D.; Savytska, N.; Fernandes, N.; Rizzu, P.; Illarionova, A.; Strauss, T.; Schwarz, S.; Kodamullil, A.; Hoeglinger, G.; Dhingra, A.; Heutink, P.
10.1101/2022.11.07.515284 — neuroscience — Posted on 2022-11-07
3133 Visual category representations in the infant brain
Xie, S.; Hoehl, S.; Moeskops, M.; Kayhan, E.; Kliesch, C.; Turtleton, B.; Koester, M.; Cichy, R. M.
10.1101/2021.11.03.466293 — neuroscience — Posted on 2022-11-07
3138 PKM2-mediated epigenetic reprogramming regulates hypoxic expression of PFKFB3 to promote breast cancer progression
Pandkar, M. R.; Raveendran, A.; Biswas, K.; Mutnuru, S. A.; Mishra, J.; Samaiya, A.; Sharan, S. K.; Shukla, S.
10.1101/2022.11.06.515384 — cancer biology — Posted on 2022-11-07
3139 Immunogenicity of non-canonical HLA-tumor ligands identified through proteogenomics
Lozano-Rabella, M.; Garcia-Garijo, A.; Palomero, J.; Yuste-Estevanez, A.; Erhard, F.; Martin-Liberal, J.; Ochoa de Olza, M.; Matos, I.; Gartner, J. J.; Ghosh, M.; Canals, F.; Vidal, A.; Piulats, J. M.; Matias-Guiu, X.; Brana, I.; Munoz-Couselo, E.; Garralda, E.; Schlosser, A.; Gros, A.
10.1101/2022.11.07.514886 — cancer biology — Posted on 2022-11-07
3146 Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection and reproduction in a wild rodent
Wanelik, K. M.; Begon, M.; Bradley, J. E.; Friberg, I. M.; Jackson, J. A.; Taylor, C. H.; Paterson, S.
10.1101/841825 — ecology — Posted on 2022-11-07
3147 Megacolonies: an alternative social organization in anemonefishes?
Mercader, M.; Zwahlen, J.; Hayashi, K.; Takamiyagi, H.; Tseng, Y.-C.; Nguyen, H.-T.; Asada, K.; Sowinski, J.; Rimer, J.; Lecchini, D.; Laudet, V.
10.1101/2022.11.06.515354 — ecology — Posted on 2022-11-07
3149 A missense mutation in zinc finger homeobox-3 (ZFHX3) impedes growth and alters metabolism and hypothalamic gene expression in mice.
Nolan, P. M.; Banks, G.; Bourbia, N.; Wilcox, A. G.; Bentley, L.; Moir, L.; Kent, L.; Hillier, R.; Wilson, D.; Barrett, P.; Dumbell, R.
10.1101/2022.05.25.493441 — physiology — Posted on 2022-11-07
3151 Joint Learning of Full-structure Noise in Hierarchical Bayesian Regression Models
Hashemi, A.; Cai, C.; Gao, Y.; Ghosh, S.; Müller, K.-R.; Nagarajan, S.; Haufe, S.
10.1101/2021.11.28.470264 — neuroscience — Posted on 2022-11-07
3153 Tumor-educated Gr1+CD11b+ cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6-JAK signaling
Peyvandi, S.; Bulliard, M.; Kauzlaric, A.; Coquoz, O.; Huang, Y.-t.; Duffey, N.; Gafner, L.; Lorusso, G.; Fournier, N.; Lan, Q.; Rüegg, C.
10.1101/2022.10.26.513889 — cancer biology — Posted on 2022-11-07
3154 Interdisciplinary analyses of Bronze Age communities from Western Hungary reveal complex population histories
Gerber, D.; Szeifert, B.; Szekely, O.; Egyed, B.; Gyuris, B.; Giblin, J. I.; Horvath, A.; Kohler, K.; Kulcsar, G.; Kustar, A.; Major, I.; Molnar, M.; Palcsu, L.; Szeverenyi, V.; Fabian, S.; Mende, B. G.; Bondar, M.; Ari, E.; Kiss, V.; Szecsenyi-Nagy, A.
10.1101/2022.02.03.478968 — genomics — Posted on 2022-11-07
3162 The transcriptional repressor Opi1 modulates the DNA Damage Response by downregulation of inositol pyrophosphates in Saccharomyces cerevisiae
Panessa, G. M.; Pires, M. R.; Pires, R. R.; Jekabson, R.; Tsuchida, E. T.; de Souza-Pinto, N. C.; da Cunha, F. M.; Cussiol, J. R. R.
10.1101/2022.11.04.515212 — cell biology — Posted on 2022-11-07
3163 Bayesian Additive Regression Trees for Genotype by Environment Interaction Models
Sarti, D. A.; Prado, E. B.; Inglis, A.; dos Santos, A. A. L.; Hurley, C.; Moral, R. d. A.; Parnell, A.
10.1101/2021.05.07.442731 — bioinformatics — Posted on 2022-11-07
3165 Optimizing and benchmarking polygenic risk scores with GWAS summary statistics
Zhao, Z.; Gruenloh, T.; Wu, Y.; Sun, Z.; Miao, J.; Wu, Y.; Song, J.; Lu, Q.
10.1101/2022.10.26.513833 — genetics — Posted on 2022-11-07
3168 Arbuscular mycorrhizal fungus Rhizophagus irregularis expresses an outwardly Shaker-like channel involved in potassium nutrition of rice (Oryza sativa L.)
Corratge-Faillie, C.; Chmaiss, L.; Zhour, H.; Lolivier, J.-P.; Audebert, P.-A.; Bui, T. X.; Seck, M.; Chinachanta, K.; Fizames, C.; Wipf, D.; Sentenac, H.; Very, A.-A.; Courty, P.-E.; Luu, D. T.
10.1101/2022.11.04.515200 — plant biology — Posted on 2022-11-07
3171 Percolate: an exponential family JIVE model to design DNA-based predictors of drug response
Mourragui, S.; Loog, M.; van Nee, M.; van de Wiel, M. A.; Reinders, M.; Wessels, L.
10.1101/2022.09.11.507473 — bioinformatics — Posted on 2022-11-07
3172 An equine Endothelin 3 cis-regulatory variant links blood pressure modulation to elite racing performance
Fegraeus, K.; Rosengren, M. K.; Naboulsi, R.; Orlando, L.; Abrink, M.; Thorsell, A.; Jouni, A.; Velie, B. D.; Raine, A.; Egner, B.; Mattsson, C. M.; Andersson, G.; Meadows, J. R.; Lindgren, G.
10.1101/2022.11.04.515141 — genetics — Posted on 2022-11-07
3175 Identification of functional immune and neuronal tumor cells in glioma
Curry, R. N.; McDonald, M. F.; Ma, Q.; Meyer, J.; Aiba, I.; Lozzi, B.; Cervantes, A.; Ko, Y.; Luna-Figuera, E.; Choi, D.-J.; Lee, Z.-F.; Jing, J.; Harmanci, A. O.; Rosenbaum, A.; He, P.; Mohila, C.; Jalali, A.; Noebels, J.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2022.11.05.515316 — cancer biology — Posted on 2022-11-06
3179 Establishment and characterisation of oviductal organoids from farm and companion animals
Lawson, E. F.; Ghosh, A.; Blanch, V.; Grupen, C. G.; Aitken, R. J.; Lim, R.; Drury, H. R.; Baker, M. A.; Gibb, Z.; Tanwar, P. S.
10.1101/2022.11.05.515300 — developmental biology — Posted on 2022-11-06
3180 Transcriptomic cytoarchitecture reveals principles of human neocortex organization
Jorstad, N. L.; Close, J.; Johansen, N.; Yanny, A. M.; Barkan, E. R.; Travaglini, K. J.; Bertagnolli, D.; Campos, J.; Casper, T.; Crichton, K.; Dee, N.; Ding, S.-L.; Gelfand, E.; Goldy, J.; Hirschstein, D.; Kroll, M.; Kunst, M.; Lathia, K.; Long, B.; Martin, N.; McMillen, D.; Pham, T.; Rimorin, C.; Ruiz, A.; Shapovalova, N.; Shehata, S.; Siletti, K.; Somasundaram, S.; Sulc, J.; Tieu, M.; Torkelson, A.; Tung, H.; Ward, K.; Callaway, E. M.; Hof, P. R.; Keene, C. D.; Levi, B. P.; Linnarsson, S.; Mitra, P. P.; Smith, K.; Hodge, R. D.; Bakken, T. E.; Lein, E. S.
10.1101/2022.11.06.515349 — neuroscience — Posted on 2022-11-06
3181 Rewarding Value or Prediction Error: Settling the debate over the role of dopamine in reward learning
Usypchuk, A.; Maes, E.; Lozzi, M.; Gardner, M.; Schoenbaum, G.; Esber, G. R.; Iordanova, M.
10.1101/2022.11.06.515338 — neuroscience — Posted on 2022-11-06
3183 The reef-building coral Galaxea fascicularis: a new model system for coral symbiosis research
Puntin, G.; Craggs, J.; Hayden, R.; Engelhardt, K.; McIlroy, S.; Sweet, M.; Baker, D. M.; Ziegler, M.
10.1101/2022.06.02.494472 — systems biology — Posted on 2022-11-06
3190 Neutralization of zoonotic simian foamy viruses: genotype-specific epitopes within the receptor-binding domain
Dynesen, L. T.; Fernandez, I.; Coquin, Y.; Delaplace, M.; Montange, T.; Njouom, R.; Bilounga-Ndongo, C.; Rey, F. A.; Gessain, A.; Backovic, M.; Buseyne, F.
10.1101/2022.11.06.515319 — microbiology — Posted on 2022-11-06
3192 Integrative single-cell characterization of hypothalamus sex-differential and obesity-associated genes and regulatory elements
Nguyen, H. P.; Chan, C. S.; Cintron, D. L.; Sheng, R.; Harshman, L.; Nobuhara, M.; Ushiki, A.; Biellak, C.; An, K.; Gordon, G. M.; Mifsud, F.; Blake, A.; Huang, E. J.; Hemberg, M.; Vaisse, C.; Ahituv, N.
10.1101/2022.11.06.515311 — neuroscience — Posted on 2022-11-06
3193 A novel antidepressant acting via allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneurons
Zhang, J.; Duan, J.; Ye, L.; Li, W.; Zhou, H.; Liu, F.; Xiaoting, T.; Xie, Y.; Huang, Y.; Sun, Y.; Zhou, H.; Huang, C.; Li, Y.; Zhu, S.; Guo, F.
10.1101/2022.11.06.514872 — neuroscience — Posted on 2022-11-06
3195 The Cousa objective: a long working distance air objective for multiphoton imaging in vivo
Yu, C.-H.; Yu, Y.; Adsit, L. M.; Chang, J. T.; Barchini, J.; Moberly, A. H.; Benisty, H.; Kim, J.; Ricci, A. J.; Fitzpatrick, D.; Cardin, J. A.; Higley, M.; Smith, G. B.; Nielsen, K. J.; Smith, I. T.; Smith, S. L.
10.1101/2022.11.06.515343 — neuroscience — Posted on 2022-11-06
3197 The role of the cerebellum in learning to predict reward: evidence from cerebellar ataxia
Nicholas, J.; Amlang, C.; Lin, C.-Y.; Montaser-Kouhsari, L.; Desai, N.; Pan, M.-K.; Kuo, S.-H.; Shohamy, D.
10.1101/2022.11.04.515251 — neuroscience — Posted on 2022-11-06
3201 Age variability and time averaging in oyster reef death assemblages
Durham, S. R.; Dietl, G. P.; Hua, Q.; Handley, J. C.; Kaufman, D.; Clark, C. P.
10.1101/2022.11.05.515182 — paleontology — Posted on 2022-11-06
3202 Identification of functional immune and neuronal tumor cells in glioma
Curry, R. N.; McDonald, M. F.; Ma, Q.; Meyer, J.; Aiba, I.; Lozzi, B.; Cervantes, A.; Ko, Y.; Luna-Figuera, E.; Choi, D.-J.; Lee, Z.-F.; Jing, J.; Harmanci, A. O.; Rosenbaum, A.; He, P.; Mohila, C.; Jalali, A.; Noebels, J.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.
10.1101/2022.11.05.515316 — cancer biology — Posted on 2022-11-06
3208 mimicINT: a workflow for microbe-host protein interaction inference
Choteau, S. A.; Cristianini, M.; Maldonado, K.; Drets, L.; Boujeant, M.; Brun, C.; Spinelli, L.; Zanzoni, A.
10.1101/2022.11.04.515250 — bioinformatics — Posted on 2022-11-06
3211 Orphan quality control shapes network dynamics and gene expression
Mark, K. G.; Kolla, S.; Garshott, D.; Martinez-Gonzalez, B.; Xu, C.; Akopian, D.; Haakonsen, D. L.; See, S. K.; Rape, M.
10.1101/2022.11.06.515368 — biochemistry — Posted on 2022-11-06
3212 Spatially resolved single-cell multiomics map of human trophoblast differentiation in early pregnancy
Arutyunyan, A.; Roberts, K.; Sheridan, M. A.; Kats, I.; Garcia-Alonso, L.; Velten, B.; Troule-Lozano, K.; Hoo, R.; Marconato, L.; Handfield, L.-F.; Tuck, L.; Gardner, L.; Mazzeo, C. I.; Kelava, I.; Prigmore, E.; Teichmann, S.; Bayraktar, O.; Moffett, A.; Stegle, O.; Turco, M. Y.; Vento-Tormo, R.
10.1101/2022.11.06.515326 — genomics — Posted on 2022-11-06
3213 Whole-body gene expression atlas of an adult metazoan
Ghaddar, A.; Armingol, E.; Huynh, C.; Gevirtzman, L.; Lewis, N. E.; Waterston, R.; O'Rourke, E.
10.1101/2022.11.06.515345 — genomics — Posted on 2022-11-06
3219 Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor
Nicastro, R.; Brohee, L.; Alba, J.; Nuechel, J.; Figlia, G.; Kipschull, S.; Gollwitzer, P.; Romero-Pozuelo, J.; Fernandes, S. A.; Lamprakis, A.; Vanni, S.; Teleman, A. A.; De Virgilio, C.; Demetriades, C.
10.1101/2022.11.06.515351 — cell biology — Posted on 2022-11-06
3220 Two RhoGEF isoforms with distinct localisation act in concert to control asymmetric cell division
Montembault, E.; Deduyer, I.; Claverie, M.-C.; Bouit, L.; Tourasse, N. J.; Dupuy, D.; McCusker, D.; Royou, A.
10.1101/2022.11.06.515358 — cell biology — Posted on 2022-11-06
3222 Dynamic growth re-orientation orchestrates flatness in the Arabidopsis leaf
Harline, K.; Fruleux, A.; Lane, B.; Mosca, G.; Strauss, S.; Tavakolian, N.; Satterlee, J. W.; Li, C.-B.; Singh, A.; Smith, R. S.; Boudaoud, A. S.; Roeder, A. H. K.
10.1101/2022.11.01.514736 — plant biology — Posted on 2022-11-06
3223 A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant co-stabilization of cyclin D1 and p21
Belanger, F.; Roussel, C.; Sawchyn, C.; Gezzar-Dandashi, S.; Ishimwe, A. B. K.; Mallette, F. A.; Wurtele, H.; Drobetsky, E. A.
10.1101/2022.04.14.488378 — molecular biology — Posted on 2022-11-06
3224 Perturbation of Lipid Bilayers by Biomimetic Photoswitches Based on Cyclocurcumin
Delova, A.; Losantos, R.; Pecourneau, J.; Bernhard, Y.; Mourer, M.; Pasc, A.; Monari, A.
10.1101/2022.09.11.507454 — biophysics — Posted on 2022-11-06
3229 Characterisation of acetogen formatotrophic potential using E. limosum
Wood, J. C.; Gonzalez-Garcia, R. A.; Daygon, D.; Talbo, G.; Plan, M. R.; Marcellin, E.; Virdis, B.
10.1101/2022.11.02.514939 — bioengineering — Posted on 2022-11-06
3230 OpenFIBSEM: an application programming interface for easy FIB/SEM automation
Cleeve, P.; Dierickx, D.; Buckley, G.; Gorelick, S.; Naegele, L.; Burne, L.; Whisstock, J. C.; de Marco, A.
10.1101/2022.11.01.514681 — cell biology — Posted on 2022-11-06
3232 Extreme tolerable winds for seabirds are determined by morphology
Nourani, E.; Safi, K.; de Grissac, S.; Anderson, D. J.; Cole, N. C.; Fell, A.; Gremillet, D.; Lempidakis, E.; Lerma, M.; McKee, J. L.; Pichegru, L.; Provost, P.; Rattenborg, N. C.; Ryan, P. G.; Santos, C. D.; Schoombie, S.; Tatayah, V.; Weimerskirch, H.; Wikelski, M.; Shepard, E.
10.1101/2022.05.02.490292 — animal behavior and cognition — Posted on 2022-11-06
3235 Reducing mitochondrial ribosomal gene expression does not alter metabolic health or lifespan in mice
Reid, K.; Daniels, E. G.; Vasam, G.; Kamble, R.; Janssens, G. E.; Hu, M.; Green, A. E.; Houtkooper, R. H.; Menzies, K. J.
10.1101/2022.11.05.515295 — cell biology — Posted on 2022-11-05
3236 XIST ribonucleoproteins promote female sex-biased autoimmunity
Dou, D. R.; Zhao, Y.; Belk, J. A.; Casey, K. M.; Chen, D. C.; Li, R.; Yu, B.; Abe, B. T.; Kraft, K.; Hellstrom, C.; Sjoberg, R.; Chang, S. E.; Feng, A.; Goldman, D. W.; Shah, A. A.; Petri, M.; Wigley, F. M.; Chung, L. S.; Fiorentino, D. F.; Lundberg, E. K.; Wutz, A.; Utz, P. J.; Chang, H.
10.1101/2022.11.05.515306 — molecular biology — Posted on 2022-11-05
3238 Heads in the clouds: marine viruses disperse bidirectionally along the natural water cycle
Rahlff, J.; Esser, S. P.; Plewka, J.; Heinrichs, M. E.; Soares, A.; Scarchilli, C.; Grigioni, P.; Wex, H.; Giebel, H.-A.; Probst, A. J.
10.1101/2022.06.21.497027 — microbiology — Posted on 2022-11-05
3239 FLAIRR-seq: A novel method for single molecule resolution of near full-length immunoglobulin heavy chain repertoires
Ford, E. E.; Tieri, D.; Rodriguez, O. L.; Francoeur, N. J.; Soto, J.; Kos, J. T.; Gibson, W. S.; Silver, C. A.; Deikus, G.; Hudson, E.; Woolley, C. R.; Beckmann, N.; Charney, A.; Mitchell, T. C.; Sebra, R. P.; Watson, C. T.; Smith, M. L.
10.1101/2022.09.24.509352 — immunology — Posted on 2022-11-05
3240 High-throughput Identification of Novel Heat Tolerance Genes via Genome-wide Pooled Mutant Screens in the Model Green Alga Chlamydomonas reinhardtii
Mattoon, E. M.; McHargue, W.; Bailey, C. E.; Zhang, N.; Chen, C.; Eckhardt, J.; Daum, C. G.; Zane, M.; Pennacchio, C.; Schmutz, J.; O'Malley, R. C.; Cheng, J.; Zhang, R.
10.1101/2022.07.13.499508 — plant biology — Posted on 2022-11-05
3243 Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities
Roider, T.; Baertsch, M. A.; Fitzgerald, D.; Voehringer, H.; Brinkmann, B. J.; Czernilofsky, F.; Knoll, M.; Llao-Cid, L.; Bruch, P.-M.; Schuerch, C. M.; Passerini, V.; Brobeil, A.; Mueller-Tidow, C.; Weigert, O.; Seiffert, M.; Nolan, G. P.; Huber, W.; Dietrich, S.
10.1101/2022.11.04.514366 — cancer biology — Posted on 2022-11-05
3244 Repurposing clemastine to target glioblastoma cell stemness
Sun, M. A.; Yang, R.; Liu, H.; Wang, W.; Song, X.; Hu, B.; Reynolds, N.; Roso, K.; Chen, L. H.; Greer, P. K.; Keir, S. T.; McLendon, R. E.; Cheng, S.-Y.; Bigner, D. D.; Ashley, D. M.; Pirozzi, C. J.; He, Y.
10.1101/2022.11.05.515291 — cancer biology — Posted on 2022-11-05
3246 Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes
Company, C.; Schmitt, M. J.; Dramaretska, Y.; Kertalli, S.; Jiang, B.; Serresi, M.; Barozzi, I.; Gargiulo, G.
10.1101/2022.11.04.515171 — bioengineering — Posted on 2022-11-05
3248 Photonic-Plasmonic Coupling Enhanced Fluorescence Enabling Digital-Resolution Ultrasensitive Protein Detection
Barya, P.; Xiong, Y.; Shepherd, S.; Gupta, R.; Akin, L. D.; Tibbs, J.; Lee, H. K.; Singamaneni, S.; Cunningham, B. T.
10.1101/2022.10.29.514360 — bioengineering — Posted on 2022-11-05
3251 Biosphere functional integrity for people and Planet
Mohamed, A.; DeClerck, F.; Verburg, P.; Obura, D.; Abrams, J. F.; Zafra-Calvo, N.; Rocha, J. C.; Estrada-Carmona, N.; Fremier, A.; Jones, S. K.; Meier, I.; Sewart-Koster, B.
10.1101/2022.06.24.497294 — ecology — Posted on 2022-11-05
3252 Model estimates of metazoans' contributions to the biological carbon pump
Pinti, J.; DeVries, T.; Norin, T.; Serra-Pompei, C.; Proud, R.; Siegel, D. A.; Kiorboe, T.; Petrik, C. M.; Andersen, K. H.; Brierley, A. S.; Visser, A. W.
10.1101/2021.03.22.436489 — ecology — Posted on 2022-11-05
3253 Establishment and characterisation of oviductal organoids from farm and companion animals
Lawson, E.; Ghosh, A.; Blanch, V.; grupen, c.; Aitken, j.; Lim, r.; drury, h.; Baker, M. A.; Gibb, Z.; Tanwar, P.
10.1101/2022.11.05.515300 — developmental biology — Posted on 2022-11-05
3256 Exploring the genome and protein space of viruses
Lu, C.; Wu, Y.; Mao, L.; Ge, X.; Wu, A.; Deng, L.; Sun, F.; Jiang, Y.; Peng, Y.
10.1101/2022.11.05.515293 — microbiology — Posted on 2022-11-05
3258 Asymmetric Signaling Across the Hierarchy of Cytoarchitecture within the Human Connectome
Parkes, L.; Kim, J. Z.; Stiso, J.; Calkins, M. E.; Cieslak, M.; Gur, R. E.; Gur, R. C.; Moore, T. M.; Ouellet, M.; Roalf, D. R.; Shinohara, R. T.; Wolf, D. H.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2022.05.13.491642 — neuroscience — Posted on 2022-11-05
3260 Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-causing mutations
Hussein, Y.; Tripathi, U.; Choudhary, A.; Nayak, R.; Peles, D.; Rosh, I.; Djamus, J.; Spiegel, R.; Garin-Shkolnik, T.; Stern, S.
10.1101/2022.11.02.514882 — neuroscience — Posted on 2022-11-05
3268 Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer
Mah, C. Y.; Nguyen, A. D. T.; Niijima, T.; Helm, M.; Dehairs, J.; Ryan, F. J.; Ryan, N.; Mills, I. G.; Swinnen, J. V.; Lynn, D. J.; Nassar, Z. D.; Butler, L. M.
10.1101/2022.11.05.515262 — cancer biology — Posted on 2022-11-05
3269 Improving annotation propagation on molecular networks through random walks: Introducing ChemWalker
Borelli, T. C.; Arini, G. S.; Feitosa, L. G. P.; Dorrestein, P. C.; Lopes, N. P.; da Silva, R. R.
10.1101/2022.11.04.514505 — bioinformatics — Posted on 2022-11-05
3272 WarpSTR: Determining tandem repeat lengths using raw nanopore signals
Sitarcik, J.; Vinar, T.; Brejova, B.; Krampl, W.; Budis, J.; Radvanszky, J.; Lucka, M.
10.1101/2022.11.05.515275 — bioinformatics — Posted on 2022-11-05
3275 CTCF mediates the Activity-by-contact derived cis-regulatory hubs
Anene Nzelu, G.; Lee, M.; Mangnier, L.; Padilla, C.; Lee, D. P.; Tan, W.; Zheng, W. H.; Li, P.; Gan, L.; Kit, C. C.; Lim, Y. P.; Wang, R. M.; Bilodeau, S.; Bureau, A.; Foo, R.
10.1101/2022.11.04.515249 — molecular biology — Posted on 2022-11-05
3276 A multifunctional LysM effector of Botrytis cinerea contributes to plant infection
Crumiere, M.; De Vallee, A.; Rascle, C.; Nahar, S.; van Kan, J. A. L.; BRUEL, C.; Poussereau, N.; CHOQUER, M.
10.1101/2022.11.05.515289 — microbiology — Posted on 2022-11-05
3280 Peptidergic modulation of motor neuron output via CART signaling at C bouton synapses
Eleftheriadis, P. E.; Pothakos, K.; Sharples, S. A.; Apostolou, P. E.; Mina, M.; Tetringa, E.; Miles, G. B.; Zagoraiou, L.
10.1101/2022.11.05.515234 — neuroscience — Posted on 2022-11-05
3281 In vivo 18F-DOPA PET imaging identifies a dopaminergic deficit in a rat model with a G51D α-synuclein mutation
Morley, V.; Singh-Dolt, K.; Alcaide-Corral, C. J.; Walton, T.; Lucatelli, C.; Mashimo, T.; Tavares, A.; Kunath, T.
10.1101/2022.11.05.515268 — neuroscience — Posted on 2022-11-05
3283 Disruption of Zea mays isochorismate synthase1 decreases PHENYLALANINE AMMONIA LYASE activity and suppresses hypersensitive response-induced metabolism
Benke, R. L.; McCoy, R. M.; Ibrahim, I. M.; Simpson, J. P.; Muro-Villanueva, F.; Zhan, R. R.; Chapple, C.; Widhalm, J. R.; Puthiyaveetil, S.; Johal, G. S.; Dilkes, B. P.
10.1101/2022.11.04.515247 — plant biology — Posted on 2022-11-05
3286 Uncovering molecular grammars of intrinsically disordered regions that organize nucleolar fibrillar centers
King, M. R.; Lin, A. Z.; Ruff, K. M.; Farag, M.; Ouyang, W.; Vahey, M. D.; Lundberg, E.; Pappu, R. V.
10.1101/2022.11.05.515292 — biophysics — Posted on 2022-11-05
3291 Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution
Tomas-Daza, L.; Rovirosa, L.; Lopez-Marti, P.; Nieto-Aliseda, A.; Serra, F.; Planas-Riverola, A.; Molina, O.; McDonald, R.; Ghevaert, C.; Cuatrecasas, E.; Costa, D.; Camos, M.; Bueno, C.; Menedez, P.; Valencia, A.; Javierre, B. M.
10.1101/2022.11.04.515239 — genomics — Posted on 2022-11-05
3294 Defects in lipid homeostasis reflect the function of TANGO2 in Acyl-CoA metabolism
Lujan, A. L.; Foresti, O.; Brouwers, N.; Mateo Farre, A.; Vignoli, A.; Wojnacki, J.; Malhotra, V.
10.1101/2022.11.05.515282 — cell biology — Posted on 2022-11-05
3296 Human influenza A virus H1N1 1 in marine mammals in California, 2019
Plancarte, M.; Kovalenko, G.; Baldassano, J.; Ramirez, A. L.; Ramirez, A. L.; Carrillo, S.; Duignan, P. J.; Goodfellow, I. G.; Bortz, E.; Dutta, J.; van Bakel, H.; Coffey, L. L.
10.1101/2022.11.04.515242 — microbiology — Posted on 2022-11-05
3297 Oral Feeding of Nanoplastics reduces Brain function of Mice by Inducing Intestinal IL-1β-producing Macrophages
Yang, Q.; Dai, H.; Chen, Y.; Wang, B.; Xu, J.; Zhang, Y.; Chen, Y.; Xu, F.; Ma, Q.; Lin, F.; Wang, C.
10.1101/2022.11.04.515261 — immunology — Posted on 2022-11-05
3300 Local and long-distance organization of prefrontal cortex circuits in the marmoset brain
Watakabe, A.; Skibbe, H.; Nakae, K.; Abe, H.; Ichinohe, N.; Rachmadi, M. F.; Wang, J.; Takaji, M.; Mizukami, H.; Woodward, A.; Gong, R.; Hata, J.; Van Essen, D. C.; Okano, H.; Ishii, S.; Yamamori, T.
10.1101/2021.12.26.474213 — neuroscience — Posted on 2022-11-05
3306 Consistent individual positions within roosts in Spix's disc-winged bats
Giacomini, G.; Chaves-Ramirez, S.; Hernandez-Pinson, A.; Barrantes, J. P.; Chaverri, G.
10.1101/2022.11.04.515223 — ecology — Posted on 2022-11-05
3309 Towards a mesoscale physical modeling framework for stereotactic-EEG recordings
Mercadal, B.; Lopez-Sola, E.; Galan-Gadea, A.; Al Harrach, M.; Sanchez, R.; Salvador, R.; Bartolomei, F.; Wendling, F.; Ruffini, G.
10.1101/2022.07.06.498826 — neuroscience — Posted on 2022-11-05
3312 Shared requirement for MYC upstream super-enhancer in tissue regeneration and cancer
Sur, I. K.; Zhao, W.; Zhang, J.; Kling Pilstrom, M.; Rozell, B.; Webb, A.; Cheng, H.; Ristimaki, A.; Katajisto, P.; Enge, M.; Rannikmae, H.; de la Roche, M. A.; Taipale, J.
10.1101/2022.11.04.515076 — cancer biology — Posted on 2022-11-05
3313 Membrane curvature governs the distribution of Piezo1 in live cells
Yang, S.; Miao, X.; Arnold, S.; Li, B.; Ly, A. T.; Wang, H.; Wang, M.; Guo, X.; Pathak, M. M.; Zhao, W.; Cox, C. D.; Shi, Z.
10.1101/2022.06.22.497259 — biophysics — Posted on 2022-11-05
3314 Rapid assessment of susceptibility of bacteria and erythrocytes to antimicrobial peptides by single-cell impedance cytometry
Troiano, C.; De Ninno, A.; Casciaro, B.; Riccitelli, F.; Park, Y.; Massoud, R.; Mangoni, M. L.; Bisegna, P.; Stella, L.; Caselli, F.
10.1101/2022.11.04.515154 — biophysics — Posted on 2022-11-05
3317 A specific mesh-like organization of human septin octameric complex drives membrane reshaping and curvature sensitivity
Nakazawa, K.; Kumar, G.; Chauvin, B.; Di Cicco, A.; Pellegrino, L.; Trichet, M.; Hajj, B.; Cabral, J.; Sain, A.; Mangenot, S.; Bertin, A.
10.1101/2022.11.02.514824 — biophysics — Posted on 2022-11-05
3318 Contrasting drugs from decoys
Sledzieski, S.; Singh, R.; Cowen, L.; Berger, B.
10.1101/2022.11.03.515086 — bioinformatics — Posted on 2022-11-04
3323 Accurate Mutation Effect Prediction using RoseTTAFold
Mansoor, S.; Baek, M.; Juergens, D.; Watson, J. L.; Baker, D.
10.1101/2022.11.04.515218 — biochemistry — Posted on 2022-11-05
3326 Ts66Yah, an upgraded Ts65Dn mouse model for Down syndrome, for only the region homologous to Human chromosome 21
Duchon, A.; Muniz Moreno, M. d. M.; Chevalier, C.; Nalesso, V.; Andre, P.; Fructuoso-Castellar, M.; Mondino, M.; Po, C.; Noblet, V.; Birling, M.-C.; Potier, M.-C.; Herault, Y.
10.1101/2022.06.06.494940 — genetics — Posted on 2022-11-05
3327 Regulatory fine-tuning and horizontal gene transfer stabilize mobile colistin resistance
Ogunlana, L. O.; Shaw, L.; Kuar, D.; Jangir, P.; Walsh, T.; Uphoff, S.; MacLean, C.
10.1101/2022.11.04.515217 — evolutionary biology — Posted on 2022-11-04
3330 ATNr : Allometric trophic models in R
Gauzens, B.; Brose, U.; Delmas, E.; Berti, E.
10.1101/2022.08.26.505404 — ecology — Posted on 2022-11-05
3331 Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier
Hu, X.; Xiao, W.; Lei, Y.; Green, A. J.; Li, X.; Maradana, M. R.; Gao, Y.; Xie, X.; Wang, R.; Chennell, G.; Basson, M. A.; Kille, P.; Maret, W.; Bewick, G.; Zhou, Y.; Hogstrand, C.
10.1101/2022.11.03.515052 — cell biology — Posted on 2022-11-04
3332 Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA scanning and recruitment to oxidized bases in living cells
D'Augustin, O.; Gaudon, V.; Siberchicot, C.; Smith, R.; Chapuis, C.; DEPAGNE, J.; Veaute, X.; BUSSO, D.; Di-Guilmi, A.-M.; Castaing, B.; Radicella, J. P.; Campalans, A.; Huet, S.
10.1101/2022.11.04.515179 — cell biology — Posted on 2022-11-05
3333 Subcytoplasmic location of translation controls protein output
Horste, E. L.; Zhen, G.; Fansler, M. M.; Chen, X.; Lee, F. C. Y.; Ule, J.; Mayr, C.
10.1101/2022.11.04.515216 — molecular biology — Posted on 2022-11-04
3334 Targeted metagenomics using probe capture detects a larger diversity of nitrogen and methane cycling genes in complex microbial communities than traditional metagenomics
Siljanen, H. M. P.; Manoharan, L.; Hilts, A. S.; Bagnoud, A.; Alves, R. J. E.; Jones, C. M.; Sousa, F.; Hallin, S.; Biasi, C.; Schleper, C.
10.1101/2022.11.04.515048 — microbiology — Posted on 2022-11-04
3335 Determinants of the microbiome spatial variability in chronic rhinosinusitis
Szaleniec, J.; Bezshapkin, V.; Krawczyk, A.; Kopera, K.; Zapala, B.; Gosiewski, T.; Kosciolek, T.
10.1101/2022.10.02.509831 — microbiology — Posted on 2022-11-04
3336 Autophagy is required in macrophages and dendritic cells to prevent early recruitment of neutrophils during Mycobacterium tuberculosis infection
Kinsella, R. L.; Kimmey, J. M.; Smirnov, A.; Woodson, R.; Gaggioli, M. R.; Chavez, S. M.; Kreamalmeyer, D.; Stallings, C. L.
10.1101/2022.11.04.515221 — immunology — Posted on 2022-11-04
3337 Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors
Demerle, C.; Gorvel, L.; Mello, M.; Pastor, S.; Degos, C.; Zarubica, A.; Angelis, F.; FIORE, F.; Nunes, J.; Malissen, B.; Greillier, L.; Guittard, G.; Luche, H.; Barlesi, F.; Olive, D.
10.1101/2022.11.04.515180 — immunology — Posted on 2022-11-05
3339 Rapid volumetric brain changes after acute psychosocial stress
Uhlig, M.; Reinelt, J. D.; Lauckner, M.; Schaare, H. L.; Kumral, D.; Mildner, T.; Babayan, A.; Moeller, H. E.; Engert, V.; Villringer, A.; Gaebler, M.
10.1101/2021.12.01.470604 — neuroscience — Posted on 2022-11-04
3340 A Peptide-Centric Quantitative Proteomics Dataset for the Phenotypic Assessment of Alzheimer's Disease
Merrihew, G. E.; Park, J.; Plubell, D.; Searle, B. C.; Keene, C. D.; Larsen, E. B.; Bateman, R.; Perrin, R. J.; Chhatwal, J. P.; Farlow, M. R.; McLean, C. A.; Ghetti, B.; Newell, K. L.; Frosh, M. P.; Montine, T.; MacCoss, M. J.
10.1101/2022.11.04.515203 — neuroscience — Posted on 2022-11-04
3341 Organ- and function-specific anatomical organization of the vagus nerve supports fascicular vagus nerve stimulation
Jayaprakash, N.; Song, W.; Toth, V.; Vardhan, A.; Levy, T.; Tomaio, J.; Qanud, K.; Mughrabi, I.; Chang, Y.-C.; Rob, M.; Daytz, A.; Abbas, A.; Nassrallah, Z.; Volpe, B.; Tracey, K. J.; Al-Abed, Y.; Datta-Chaudhuri, T.; Miller, L.; Barbe, M.; Lee, S.; Zanos, T.; Zanos, S.
10.1101/2022.03.07.483266 — neuroscience — Posted on 2022-11-04
3343 Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem stem cell adhesion and migration during aging
Yeo, R. W.; Zhou, O. Y.; Zhong, B. L.; Sun, E. D.; Navarro Negredo, P.; Nair, S.; Sharmin, M.; Ruetz, T. J.; Wilson, M.; Kundaje, A.; Dunn, A. R.; Brunet, A.
10.1101/2021.03.29.437585 — neuroscience — Posted on 2022-11-05
3348 The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2
Chaib, S.; Lopez-Dominguez, J. A.; Lalinde, M.; Prats, N.; Marin, I.; Meyer, K.; Munoz, M. I.; Aguilera, M.; Mateo, L.; Attolini, C. S.-O.; Llanos, S.; Escorihuela, M.; Perez-Ramos, S.; Al-Shahrour, F.; Cash, T. P.; Tchkonia, T.; Kirkland, J. L.; Arribas, J.; Serrano, M.
10.1101/2022.11.04.501681 — cancer biology — Posted on 2022-11-04
3349 GSK-3484862 targets DNMT1 for degradation in cells
Chen, Q.; Zeng, Y.; Hwang, J. W.; Liu, B.; Dai, N.; Correa, I. R.; Estecio, M. R.; Zhang, X.; Santos, M. A.; Chen, T.; Cheng, X.
10.1101/2022.11.03.514954 — cancer biology — Posted on 2022-11-04
3350 Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
Nigam, N.; Bernard, B.; Kim, S.; Burkitt, K.; Tsai, D.; Robbins, Y.; Sievers, C.; Allen, C. T.; Bennett, R. L.; Tettey, T. T.; Carter, B.; Bao, R.; Rinaldi, L.; Lingen, M. W.; Sater, H.; Edmondson, E. F.; Cheng, H.; Luo, X.; Brennan, K.; Chen, C.; Sevilla, S.; Murali, M.; Sakata, S.; Takeuchi, K.; Nakamura, Y.; Uppaluri, R.; Sunwoo, J. B.; Van Waes, C.; Licht, J. D.; Hager, G. L.; Saloura, V.
10.1101/2022.11.04.515098 — cancer biology — Posted on 2022-11-04
3351 Flotillin-2 regulates EGFR activation, degradation, and cancer growth
Wisniewski, D. J.; Liyasova, M. S.; Korrapati, S.; Zhang, X.; Ratnayake, S.; Chen, Q.; Gilbert, S. F.; Catalano, A.; Voeller, D.; Meerzaman, D.; Guha, U. J.; Porat-Shliom, N.; Annunziata, C.; Lipkowitz, S.
10.1101/2022.03.11.483779 — cancer biology — Posted on 2022-11-04
3353 TCR_Explore: a novel webtool for T cell receptor repertoire analysis
Mullan, K. A.; Zhang, J. B.; Jones, C. M.; Goh, S. J. R.; Revote, J.; Illing, P. T.; Purcell, A. W.; La Gruta, N. L.; Li, C.; Mifsud, N. A.
10.1101/2022.11.03.514642 — bioinformatics — Posted on 2022-11-04
3358 Machine-learning based detection of adventitious microbes in T-cell therapy cultures using long read sequencing
Strutt, J. P. B.; Natarajan, M.; Lee, E.; Barone, P. W.; Wolfrum, J. M.; Williams, R. B. H.; Sin, W. X.; Rice, S. A.; Springs, S. L.
10.1101/2022.11.03.514634 — bioinformatics — Posted on 2022-11-04
3362 Molecular understanding of Eubacterium limosum chemostat methanol metabolism
Wood, J. C.; Gonzalez-Garcia, R. A.; Daygon, D.; Talbo, G.; Plan, M. R.; Marcellin, E.; Virdis, B.
10.1101/2022.11.04.514945 — bioengineering — Posted on 2022-11-04
3363 Magnetic Levitation and Sorting of Neoplastic Circulating Cell Hybrids
Liang, K.; Yaman, S.; Patel, R. K.; Parappilly, M. S.; Walker, B. S.; Wong, M. H.; Durmus, N. G.
10.1101/2022.11.03.515127 — bioengineering — Posted on 2022-11-04
3364 Molecular machines stimulate intercellular calcium waves and cause muscle contraction
Beckham, J. L.; van Venrooy, A. R.; Kim, S.; Li, G.; Li, B.; Duret, G.; Arnold, D.; Zhao, X.; Santos, A. L.; Chaudhry, G.; Robinson, J. T.; Tour, J.
10.1101/2022.11.04.515191 — bioengineering — Posted on 2022-11-04
3365 Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes
Gargiulo, G.; Company, C.; Schmitt, M. J.; Dramaretska, Y.; Kertalli, S.; Jiang, B.; Serresi, M.; Barozzi, I.
10.1101/2022.11.04.515171 — bioengineering — Posted on 2022-11-04
3366 Nasopharyngeal competition dynamics are likely to be altered following vaccine introduction: bacteriocin prevalence and diversity among Icelandic and Kenyan pneumococci
Butler, M. E.; Jansen van Rensburg, M. J.; Karani, A.; Mvera, B.; Akech, D.; Akter, A.; Forrest, C.; van Tonder, A. J.; Quirk, S. J.; Haraldsson, G.; Bentley, S. D.; Erlendsdottir, H.; Haraldsson, A.; Kristinsson, K. G.; Scott, J. A. G.; Brueggemann, A. B.
10.1101/2022.11.03.514821 — genomics — Posted on 2022-11-04
3370 Drivers of dispersal and diversification in bromeliads
Kessous, I. M.; Farooq, H.; Testo, W.; Torres Jimenez, M. F.; Neves, B.; Pinto, A. R.; Salgueiro, F.; Costa, A. F.; Bacon, C.
10.1101/2022.11.04.515068 — evolutionary biology — Posted on 2022-11-04
3371 Sex Chromosome Heteromorphism and the Fast-X Effect in Poeciliids
Darolti, I.; Fong, L.; Sandkam, B. A.; Metzger, D. C. H.; Mank, J. E.
10.1101/2021.09.03.458929 — evolutionary biology — Posted on 2022-11-04
3373 Development of an insect sample fractionizer for biodiversity research
Hoerren, T.; Sorg, M.; Hallmann, C.; Stenmans, W.; Ssymank, A.; Theumert, H.; Fleischer, B.; Schwan, H.
10.1101/2022.11.04.515206 — ecology — Posted on 2022-11-04
3376 Microplastics are present in follicular fluid and compromise gamete function in vitro: Is the Anthropocene throw-away society throwing away fertility?
Grechi, N.; Franko, R.; Rajaraman, R.; Stoeckl, J. B.; Trapphoff, T.; Dieterle, S.; Frohlich, T.; Noonan, M.; de Almeida Monteiro Melo Ferraz, M.
10.1101/2022.11.04.514813 — developmental biology — Posted on 2022-11-04
3377 Spatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function
Roman-Fernandez, A.; Mansour, M.; Kugeratski, F. G.; Anand, J.; Sandilands, E.; Galbraith, L.; Rakovic, K.; Freckmann, E. C.; Cumming, E. M.; Park, J.; Nikolatou, K.; Lilla, S.; Shaw, R.; Strachan, D.; Mason, S.; Patel, R.; McGarry, L.; Katoch, A.; Campbell, K.; Nixon, C.; Miller, C. J.; Leung, H. Y.; Le Quesne, J.; Norman, J. C.; Zanivan, S. R.; Blyth, K.; Bryant, D. M.
10.1101/2022.11.04.515043 — cell biology — Posted on 2022-11-04
3378 V0-ATPase downregulation induces MVID-like brush border defects independently of apical trafficking in the mammalian intestine
Bidaud-Meynard, A.; Nicolle, O.; Bourdais, A.; Duclos, M.; Saleh, J.; Ruemmele, F.; Farin, H. F.; Delacour, D.; Moshous, D.; Michaux, G.
10.1101/2022.11.04.515188 — cell biology — Posted on 2022-11-04
3383 Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches
Asahi, T.; Abe, S.; Cui, G.; Shimba, A.; Nabekura, T.; Miyachi, H.; Kitano, S.; Ohira, K.; Dijkstra, J. M.; Miyazaki, M.; Shibuya, A.; Ohno, H.; Ikuta, K.
10.1101/2022.11.03.514990 — immunology — Posted on 2022-11-04
3384 Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced bactericidal activity
Darroch, H.; Keerthisinghe, P.; Sung, Y. J.; Prankerd-Gough, A.; Crosier, P.; Astin, J.; Hall, C.
10.1101/2022.11.03.515114 — immunology — Posted on 2022-11-04
3385 Tuning the potency and therapeutic window of ImmTAC molecules by affinity modulation
Robertson, I. B.; Mulvaney, R. M.; Dieckmann, N.; Vantellini, A.; Canestraro, M.; Amicarella, F.; O'Dwyer, R.; Cole, D. K.; Harper, S.; Dushek, O.; Kirk, P.
10.1101/2022.11.03.511676 — immunology — Posted on 2022-11-04
3386 A cellular and spatial map of salivary glands at single cell resolution reveals the functional basis of tertiary lymphoid structure formation in Sjogren's syndrome
Nayar, S.; Turner, J. D.; Asam, S.; Fennell, E.; Pugh, M.; Colafrancesco, S.; Berardicurti, O.; Smith, C. G.; Flint, J.; Teodosio, A.; Iannizzotto, V.; Gardner, D. G.; Roon, J. v.; Korsunsky, I.; Roche Fibroblast Network Consortium, ; Bowman, S. J.; Ng, W.-F.; Croft, A. P.; Filer, A.; Fisher, B. A.; Buckley, C. D.; Barone, F.
10.1101/2022.11.03.514908 — immunology — Posted on 2022-11-04
3388 gMCStool: automated network-based tool to search for metabolic vulnerabilities in cancer
Valcarcel, L. V.; San Jose-Eneriz, E.; Ordonez, R.; Apaolaza, I.; Valcarcel, A.; Garate, L.; San Miguel, J.; Pineda-Lucena, A.; Agirre, X.; Prosper, F.; Planes, F. J.
10.1101/2022.11.03.514827 — systems biology — Posted on 2022-11-04
3391 Towards Environmental Control of Microbiomes
Sharpless, W. A.; Sander, K. B.; Song, F.; Kuehl, J. V.; Arkin, A. P.
10.1101/2022.11.04.515211 — systems biology — Posted on 2022-11-04
3393 Selective degradation of ARF monomers controls auxin response in Marchantia
Das, S.; de Roij, M.; Bellows, S.; Kohlen, W.; Farcot, E.; Weijers, D.; Borst, J. W.
10.1101/2022.11.04.515187 — plant biology — Posted on 2022-11-04
3394 Arbuscular mycorrhizal fungus Rhizophagus irregularis expresses an outwardly Shaker-like channel involved in potassium nutrition of rice (Oryza sativa L.)
Luu, D. T.; Corratge-Faillie, C.; Chmaiss, L.; Zhour, H.; Lolivier, J.-P.; Audebert, P.-A.; Bui, T. X.; Seck, M.; Chinachanta, K.; Fizames, C.; Wipf, D.; Sentenac, H.; Very, A.-A.; Courty, P.-E.
10.1101/2022.11.04.515200 — plant biology — Posted on 2022-11-04
3395 Methylglyoxal controls tomato fruit ripening by regulating ethylene biosynthesis
Kumar, R.; Gambhir, P.; Raghuvanshi, U.; Parida, A.; Kujur, S.; Sharma, S.; Sharma, A. K.; Sopory, S. K.
10.1101/2022.11.03.515062 — plant biology — Posted on 2022-11-04
3396 OsPSTOL1 is prevalent in upland rice and its expression in wheat enhances root growth and hastens low phosphate signaling
Kettenburg, A. T.; Lopez, M. A.; Yogendra, K.; Prior, M. J.; Rose, T.; Bimson, S.; Heuer, S.; Roy, S. J.; Bailey-Serres, J.
10.1101/2022.11.03.515113 — plant biology — Posted on 2022-11-04
3397 Nuclei isolation protocol from diverse angiosperm species
Li, C.; Wood, J. C.; Deans, N. C.; Jarrell, A. F.; Martin, D.; Mailloux, K.; Wang, Y.-W.; Buell, C. R.
10.1101/2022.11.03.515090 — plant biology — Posted on 2022-11-04
3398 Enteric Glial Cell Network Function is Required for Epithelial Barrier Restitution following Intestinal Ischemic Injury in the Early Postnatal Period
Ziegler, A. L.; Erwin, S. J.; Caldwell, M. L.; Touvron, M.; Pridgen, T. A.; Magness, S. T.; Odle, J.; Van Landeghem, L. L.; Blikslager, A. T.
10.1101/2022.11.04.514575 — physiology — Posted on 2022-11-04
3399 Oral mTOR Inhibition Limits And Reduces Actinic Keratosis And Cutaneous Squamous Cell Carcinoma In A UVB-Induced Mouse Model
Booty, M. G.; Komalo, B.; Hosny, A.; Headland, S. E.; Fernandez-Figueras, M.-T.; Nguyen, A. M.; Cousin, W.; Heinrich, J.; Nicolaisen, L.; DeVay, R. M.; White, B.; elabd, c.
10.1101/2022.11.03.513568 — pharmacology and toxicology — Posted on 2022-11-04
3400 Ceramide synthase 6 (CerS6) promotes alcohol-induced fatty liver by promoting metabolic dysfunction and upregulating lipid droplet-associated proteins
Jeon, S.; Scorletti, E.; Buyco, D.; Lin, C.; Saiman, Y.; Martin, J.; Hooks, R.; Ogretmen, B.; Argemi, J.; Melo, L.; Bataller, R.; Carr, R. M.
10.1101/2022.11.03.514971 — pathology — Posted on 2022-11-04
3401 Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
Fischer, S.; Trinh, V. T.; Simon, C.; Weber, L. M.; Forne, I.; Nist, A.; Bange, G.; Abendroth, F.; Stiewe, T.; Steinchen, W.; Liefke, R.; Vazquez, O.
10.1101/2022.11.04.515028 — cancer biology — Posted on 2022-11-04
3406 DeepOM: Single-molecule optical genome mapping via deep learning
Nogin, Y.; Detinis Zur, T.; Margalit, S.; Barzilai, I.; Alalouf, O.; Ebenstein, Y.; Shechtman, Y.
10.1101/2022.11.04.512597 — bioinformatics — Posted on 2022-11-04
3409 ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins.
Abanades, B.; Wong, W. K.; Boyles, F.; Georges, G.; Bujotzek, A.; Deane, C. M.
10.1101/2022.11.04.514231 — bioinformatics — Posted on 2022-11-04
3413 Stronger transcriptomic response to feed intake in the duodenum of pig with high feed efficiency from a divergent selection experiment
Devailly, G.; Feve, K.; Saci, S.; Sarry, J.; Valiere, S.; Lluch, J.; Bouchez, O.; Ravon, L.; Billon, Y.; Gilbert, H.; Beaumont, M.; Demars, J.
10.1101/2022.11.03.515018 — genomics — Posted on 2022-11-04
3414 Sequencing by avidity enables high accuracy with low reagent consumption
Arslan, S.; Garcia, F. J.; Guo, M.; Kellinger, M. W.; Kruglyak, S.; LeVieux, J. A.; Mah, A. H.; Wang, H.; Zhao, J.; Zhou, C.; Altomare, A.; Bailey, J.; Byrne, M. B.; Chang, C.; Chen, S. X.; Dennler, C. N.; Dien, V. T.; Fuller, D.; Kelley, R.; Khandan, O.; Klein, M. G.; Kim, M.; Lajoie, B. R.; Lin, B.; Liu, Y.; Lopez, T.; Mains, P. T.; Price, A. D.; Robertson, S. R.; Taylor-Weiner, H.; Tippana, R.; Tomaney, A. B.; Zhang, S.; Ambroso, M. R.; Bajari, R.; Bellizzi, A. M.; Benitez, C. B.; Berard, D. R.; Berti, L.; Blease, K. N.; Blum, A. P.; Boddicker, A. M.; Bondar, L.; Brown, C.; Bui, C. A.; Call
10.1101/2022.11.03.514117 — genomics — Posted on 2022-11-04
3416 CrusTome: A transcriptome database resource for large-scale analyses across Crustacea
Perez-Moreno, J. L.; Kozma, M. T.; DeLeo, D. M.; Bracken-Grissom, H. D.; Durica, D. S.; Mykles, D. L.
10.1101/2022.11.03.515067 — genomics — Posted on 2022-11-04
3417 Modest transcriptomic response to polyploidization in allohexaploid wheat synthetics
Banouh, M.; Armisen, D.; Bouguennec, A.; Huneau, C.; Sow, M.-D.; Pont, C.; Salse, J.; Civan, P.
10.1101/2022.11.04.515153 — genomics — Posted on 2022-11-04
3418 An equine Endothelin 3 cis-regulatory variant links blood pressure modulation to elite racing performance
Fegraeus, K.; Rosengren, M. K.; Naboulsi, R.; Orlando, L.; Abrink, M.; Thorsell, A.; Jouni, A.; Velie, B. D.; Raine, A.; Egner, B.; Mattsson, C. M.; Andersson, G.; Meadows, J. R.; Lindgren, G.
10.1101/2022.11.04.515141 — genetics — Posted on 2022-11-04
3419 Development of a novel oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia.
Morini, E.; Chekuri, A.; Logan, E.; Bolduc, J.; Kirchner, E.; Salani, M.; Krauson, A.; Narasimhan, J.; Gabbeta, V.; Grover, S.; Dakka, A.; Mollin, A.; Jung, S.; Zhao, X.; Zhang, N.; Zhang, S.; Arnold, M.; Woll, M.; Naryshkin, N.; Weetall, M.; Slaugenhaupt, S.
10.1101/2022.11.04.515198 — genetics — Posted on 2022-11-04
3423 Ancient dolphin genomes reveal rapid repeated adaptation to coastal waters
Louis, M.; Korlevic, P.; Nykanen, M.; Archer, F.; Berrow, S.; Brownlow, A.; Lorenzen, E.; O'Brien, J.; Post, K.; Racimo, F.; Rogan, E.; Rosel, P. E.; Sinding, M.-H. S.; van der Es, H.; Wales, N.; Fontaine, M. C.; Gaggiotti, O. E.; Foote, A. D.
10.1101/2022.11.03.515020 — evolutionary biology — Posted on 2022-11-04
3425 Host-driven temperature dependence of viral infection in honey bees
Palmer-Young, E. C.; Ryabov, E. V.; Markowitz, L.; Boncristiani, D. L.; Grubbs, K.; Pawar, A.; Peterson, R.; Evans, J. D.
10.1101/2022.11.03.515055 — ecology — Posted on 2022-11-04
3432 Transcriptomic landscape of early hair follicle and epidermal development
Sulic, A.-M.; Das Roy, R.; Papagno, V.; Lan, Q.; Saikkonen, R.; Jernvall, J.; Thesleff, I.; Mikkola, M. L.
10.1101/2022.11.03.515012 — developmental biology — Posted on 2022-11-04
3434 Integrated transcriptome and lineage analyses reveal novel catecholaminergic cardiomyocytes contributing to the cardiac conduction system in murine heart
Sun, T.; Grassam-Rowe, A.; Pu, Z.; Ren, H.; An, Y.; Guo, X.; Hu, W.; Liu, Y.; Li, Y.; Liu, Z.; Kou, K.; Ou, X.; Chen, T.; Fan, X.; Liu, Y.; Tu, S.; He, Y.; Ren, Y.; Chen, A.; Shang, Z.; Xia, Z.; Miquerol, L.; Smart, N.; Zhang, H.; Tan, X.; Shou, W.; Lei, M.
10.1101/2022.11.04.515095 — cell biology — Posted on 2022-11-04
3436 IGF2BP2 is Induced by Stress in the Heart and Mediates Dilated Cardiomyopathy
Krumbein, M.; Oberman, F.; Cinnamon, Y.; Golomb, M.; May, D.; Vainer, G.; Belzer, V.; Meir, K.; Fridman, I.; Haybaeck, J.; Poelzl, G.; Kehat, I.; Beeri, R.; Kessler, S.; Yisraeli, J. K.
10.1101/2022.11.03.515033 — cell biology — Posted on 2022-11-04
3438 Mosquito bites and stages specific antibody responses against Plasmodium falciparum in southern Ghana
Kwapong, S. S.; Asare, K. K.; Kusi, K. A.; Pappoe, F.; Ndam, N.; Tahar, R.; Poinsignon, A.; Amoah, L. E.
10.1101/2022.11.03.514987 — immunology — Posted on 2022-11-04
3441 IL-17A promotes epithelial cell IL-33 production during nematode lung migration
Ajendra, J.; Pearson, S.; Parkinson, J.; Chan, B. H. K.; McSorley, H. J.; Sutherland, T. E.; Allen, J. E.
10.1101/2022.11.03.515050 — immunology — Posted on 2022-11-04
3442 Glucocorticoid involvement in reproductive biology
Mullins, L. J.; Morley, S. D.; Kenyon, C. J.; Mullins, J. J.
10.1101/2022.11.03.515013 — physiology — Posted on 2022-11-04
3443 Discovery of aphid-transmitted Rice tiller inhibition virus from native plants through metagenomic sequencing
Yan, W.; Zhu, Y.; Liu, W.-C.; Zou, C.-w.; Jia, B.; Chen, Z.-Q.; Han, Y.; Wu, J.; Yang, D.-L.; Chen, B.; Li, R.; Ding, S.-W.; Wu, Q.; Guo, Z.
10.1101/2022.11.04.515094 — pathology — Posted on 2022-11-04
3448 A CMOS-based highly scalable flexible neural electrode interface
Zhao, E. T.; Hull, J.; Hemed, N.; Ulusan, H.; Bartram, J.; Zhang, A.; Wang, P.; Pham, A.; Ronchi, S.; Huguenard, J.; Hierlemann, A.; Melosh, N.
10.1101/2022.11.03.514455 — bioengineering — Posted on 2022-11-04
3450 SOX9 elongates cell cycle phases and biases fate decisions in human intestinal stem cells
Burclaff, J.; Bliton, R. J.; Breau, K. A.; Cotton, M. J.; Hinesley, C. M.; Ok, M. T.; Sweet, C. W.; Zheng, A.; Bankaitis, E. D.; Ariel, P.; Magness, S. T.
10.1101/2022.11.03.514885 — cell biology — Posted on 2022-11-04
3451 Extraintestinal survival and host immune response to Vibrio cholerae
Duodu, S.; Agyei, F. K.; Adade, N. E.; Anabire, N. G.; Appiah, V.; Bediako, Y.
10.1101/2022.11.03.515087 — microbiology — Posted on 2022-11-04
3452 Loss of Mfn1 but not Mfn2 enhances adipogenesis
Mann, J. P.; Tabara, L.; Alvarez-Guaita, A.; Dong, L.; Haider, A.; Lim, K.; Tandon, P.; Minchin, J. E.; O'Rahilly, S.; Patel, S.; Fazakerley, D. J.; Prudent, J.; Semple, R. K.; Savage, D. B.
10.1101/2022.11.04.515167 — cell biology — Posted on 2022-11-04
3453 First reported detection of the mobile colistin resistance genes, mcr-8 and mcr-9, in the Irish environment
Cahill, N.; Hooban, B.; Fitzhenry, K.; Joyce, A.; OConnor, L.; Miliotis, G.; McDonagh, F.; Burke, L.; Chueiri, A.; Farrell, M. L.; Bray, J. E.; Delappe, N.; Brennan, W.; Prendergast, D.; Gutierrez, M.; Burgess, C.; Cormican, M.; Morris, D.
10.1101/2022.11.03.515100 — microbiology — Posted on 2022-11-04
3454 Depleting cationic lipids involved in antimicrobial resistance drives adaptive lipid remodeling in Enterococcus faecalis
Rashid, R.; Nair, Z. J.; Chia, D. M. H.; Chong, K. K. L.; Cazenave-Gassiot, A.; Morley, S. A.; Allen, D. K.; Chen, S. L.; Chng, S.-S.; Wenk, M. R.; Kline, K. A.
10.1101/2022.11.04.515160 — microbiology — Posted on 2022-11-04
3457 Antigen self-anchoring onto bacteriophage T5 capsid-like particles for vaccine design
VERNHES, E.; LARBI CHERIF, L.; DUCROT, N.; OULDALI, M.; ZIG, L.; SIDIBE, N. d.; HOOS, S.; RAMIREZ-CHAMORRO, L.; RENOUARD, M.; ROSSIER, O.; ENGLAND, P.; SCHOEHN, G.; BOULANGER, P.; BENIHOUD, K.
10.1101/2022.11.03.515007 — immunology — Posted on 2022-11-04
3458 Rational Chemical Design of Molecular Glue Degraders
Toriki, E. S.; Papatzimas, J. W.; Nishikawa, K.; Dovala, D.; McGregor, L. M.; Hesse, M. J.; McKenna, J. M.; Tallarico, J. A.; Schirle, M.; Nomura, D. K.
10.1101/2022.11.04.512693 — biochemistry — Posted on 2022-11-04
3459 Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock
Tariq, D.; Maurici, N.; Bartholomai, B.; Chandrasekaran, S.; Dunlap, J. C.; Bah, A.; CRANE, B. R.
10.1101/2022.11.03.515097 — biochemistry — Posted on 2022-11-04
3461 Development of a high-throughput starch digestibility assay reveals wide variation among the A. E. Watkins wheat landrace collection
Zafeiriou, P.; Savva, G. M.; Ahn-Jarvis, J. H.; Warren, F. J.; Pasquariello, M.; Griffiths, S.; Seung, D.; Hazard, B. A.
10.1101/2022.11.04.515016 — biochemistry — Posted on 2022-11-04
3462 Cryo-EM structure of the chain-elongating E3 ligase UBR5
Hodakova, Z.; Grishkovskaya, I.; Brunner, H. L.; Bolhuis, D. L.; Belacic, K.; Schleiffer, A.; Kotisch, H.; Brown, N. G.; Haselbach, D.
10.1101/2022.11.03.515015 — biochemistry — Posted on 2022-11-04
3464 A condensate forming tether for lariat debranching enzyme is defective in non-photosensitive trichiothiodystrophy
Townley, B. A.; Buerer, L.; Bacolla, A.; Rusanov, T.; Schmidt, N.; Srivatsan, S. N.; Clark, N. E.; Mansoori, F.; Sample, R. A.; Brickner, J. R.; McDonald, D.; Tsai, M.-S.; Walter, M.; Wozniak, D. F.; Holehouse, A. S.; Tainer, J.; Fairbrother, W.; Mosammaparast, N.
10.1101/2022.11.03.515106 — biochemistry — Posted on 2022-11-04
3466 Detection and Whole Genome of Japanese Encephalitis Virus Genotype III strains isolated from Indian Pig and Mosquito vector
Pegu, S. R.; Das, P. J.; Sonowal, J.; Sengar, G. S.; Deb, R.; Rajkhowa, S.; Choudhury, M.; Gulati, B. R.; Gupta, V. K.
10.1101/2022.11.03.515130 — genomics — Posted on 2022-11-04
3467 RNA m6A and 5hmC regulate monocyte and macrophage gene expression programs
Pinello, N.; Song, R.; Lee, Q.; Calonne, E.; Duan, K.-L.; Wong, E.; Tieng, J.; Mehravar, M.; Rong, B.; Lan, F.; Roediger, B.; Ma, C.-J.; Yuan, B.-F.; Rasko, J. E.; Larance, M.; Ye, D.; Fuks, F.; Wong, J. J.-L.
10.1101/2022.11.03.514952 — molecular biology — Posted on 2022-11-04
3468 PRMT5 links lipid metabolism to contractile function of skeletal muscles
Kim, K. H.; Jia, Z.; Strange, M. M.; Chen, J.; Qiu, J.; Oprescu, S. N.; Chen, X.; Syed, S. A.; Yue, F.; Roseguini, B. T.; Imbalzano, A. N.; Hu, C.; Kuang, S.
10.1101/2022.11.04.515165 — molecular biology — Posted on 2022-11-04
3469 Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments
Musawi, S.; Donnio, L.-M.; Magnani, C.; Binda, O.; Cote, J.; Lomonte, P.; Mari, P.-O.; Giglia-Mari, G.
10.1101/2022.11.04.515196 — molecular biology — Posted on 2022-11-04
3473 Assessment of infant outgrowth of cow's milk allergy in relation to the faecal microbiome and metaproteome
Hendrickx, D. M.; An, R.; Boeren, S.; Mutte, S. K.; PRESTO study team, ; Lambert, J. M.; Belzer, C.
10.1101/2022.11.03.514997 — microbiology — Posted on 2022-11-04
3474 Prediction of elimination of intrahepatic cccDNA in hepatitis B virus-infected patients by a combination of noninvasive viral markers
Iwami, S.; Iwamoto, M.; Wakita, T.; Watashi, K.; Perelson, A. S.; Tanaka, Y.; Dandri, M.; Aihara, K.; Muramatsu, M.; Iwami, S.; Kawakami, E.; Allweiss, L.; Tangkijvanich, P.; Chuaypen, N.; Atsukawa, M.; Matsui, T.; Tsukuda, S.; Hayashi, S.; Kim, K. S.; Kitagawa, K.; Nishiyama, T.; Nakamura, N.; Fujita, Y.
10.1101/2022.11.04.515164 — microbiology — Posted on 2022-11-04
3475 Description of Gloeomargarita ahousahtiae sp. nov., a thermophilic member of the order Gloeomargaritales with intracellular carbonate inclusions
Bacchetta, T.; Lopez-Garcia, P.; Gutierrez-Preciado, A.; Mehta, N.; Skouri-Panet, F.; Benzerara, K.; Ciobanu, M.; Yubuki, N.; Tavera, R.; Moreira, D.
10.1101/2022.11.03.515036 — microbiology — Posted on 2022-11-04
3477 MorphoAST: A Machine Learning Workflow for Sub-Doubling Time Single Cell Antimicrobial Susceptibility Testing
Tjandra, K. C.; Ram-Mohan, N. C.; Roshardt, M.; Qu, Z.; Zudock, E. J.; Mach, K. E.; Erminaga, O.; Liao, J. C.; Yang, S.; Wong, P. K.
10.1101/2022.11.03.515093 — microbiology — Posted on 2022-11-04
3478 Shigella induces epigenetic reprogramming of zebrafish neutrophils
Gomes, M. C.; Brokatzky, D.; Bielecka, M. K.; Wardle, F. C.; Mostowy, S.
10.1101/2022.11.03.515069 — microbiology — Posted on 2022-11-04
3481 Investigating the zoonotic origin of the Marburg virus outbreak in Guinea in 2021
Makenov, M. T.; Boumbaly, S.; Tolno, F. R.; Sacko, N.; Leno, T. N.; Mansare, O.; Kolie, B.; Stukolova, O.; Morozkin, E.; Kholodilov, I.; Zhurenkova, O.; Fyodorova, M.; Akimkin, V.; Popova, A.; Conde, N.; Boiro, M. Y.; Karan, L.
10.1101/2022.11.03.514981 — microbiology — Posted on 2022-11-04
3482 Integrated protein-protein interaction and RNA interference screens reveal novel restriction and dependency factors for a tick-borne flavivirus in its human host
Sourisseau, M.; Unterfinger, Y.; Lemasson, M.; Caignard, G.; Piumi, F.; Grot, A.; Moutailler, S.; Vitour, D.; Coulpier, M.; Lacour, S. A.; Richardson, J.
10.1101/2022.11.03.514869 — microbiology — Posted on 2022-11-04
3484 Cryo-electron microscopy of the f1 filamentous phage reveals a new paradigm in viral infection and assembly
Conners, R.; Leon-Quezada, R. I.; McLaren, M.; Bennett, N.; Daum, B.; Rakonjac, J.; Gold, V.
10.1101/2022.11.03.514279 — microbiology — Posted on 2022-11-04
3485 Autophagy protects against high-dose Mycobacterium tuberculosis infection
Feng, S.; Nehls, E. M.; Kinsella, R. L.; Chavez, S. M.; Naik, S. K.; McKee, S. R.; Dubey, N.; Samuels, A.; Swain, A.; Cui, X.; Hendrix, S. V.; Woodson, R.; Kreamalmeyer, D.; Smirnov, A.; Artyomov, M. N.; Virgin, H. W.; Wang, Y.-T.; Stallings, C. L.
10.1101/2022.11.04.515158 — microbiology — Posted on 2022-11-04
3488 HIV-1 Vpr induces ciTRAN to prevent transcriptional silencing of the provirus
Bhardwaj, V.; Singh, A.; Dalavi, R.; Ralte, L.; Chawngthu, R. L.; Senthil Kumar, N.; Vijay, N.; Chande, A.
10.1101/2022.11.04.515166 — microbiology — Posted on 2022-11-04
3493 Seeing our hand or a tool during visually-guided actions: different effects on the somatosensory and visual cortices
Mathieu, B.; Abillama, A.; More, S.; Mercier, C.; Simoneau, M.; Danna, J.; Mouchnino, L.; Blouin, J.
10.1101/2022.11.04.515184 — neuroscience — Posted on 2022-11-04
3495 Size-Dependent Transport of Cerebrospinal Fluid Tracers in Mouse Brain Observed by Dynamic Contrast-Enhanced MRI
Zhu, Y.; Wang, G.; Kolluru, C.; Gu, Y.; Gao, H.; Zhang, J.; Wang, Y.; Wilson, D. L.; Zhu, X.; Flask, C. A.; Yu, X.
10.1101/2022.11.03.515111 — neuroscience — Posted on 2022-11-04
3498 Distinct feedforward and feedback pathways for cell-type specific attention effects in macaque V4.
Spyropoulos, G.; Schneider, M.; van Kempen, J.; Gieselmann, M. A.; Thiele, A.; Vinck, M.
10.1101/2022.11.04.515185 — neuroscience — Posted on 2022-11-04
3500 Lipidomic alterations in the cerebral cortex and white matter in sporadic Alzheimer's disease
Obis, E.; Sol, J.; Andres-Benito, P.; Martin-Gari, M.; Mota-Martorell, N.; Galo-Licona, J. D.; Pinol-Ripoll, G.; Portero-Otin, M.; Ferrer, I.; Jove, M.; Pamplona, R.
10.1101/2022.11.04.515175 — neuroscience — Posted on 2022-11-04
3501 Faecal microbiota transplantation from Alzheimer's participants induces impairments in neurogenesis and cognitive behaviours in rats
Grabrucker, S.; Marizzoni, M.; Silajdzic, E.; Lopizzo, N.; Mombelli, E.; Nicolas, S.; Dohm-Hansen, S.; Scassellati, C.; Moretti, D.; Rosa, M.; Hoffmann, K.; English, J. A.; Lavelle, A.; O'Neill, C.; Thuret, S.; Cattaneo, A.; Nolan, Y. M.
10.1101/2022.11.04.515189 — neuroscience — Posted on 2022-11-04
3502 A primary sensory cortical interareal feedforward inhibitory circuit for tacto-visual integration
Weiler, S.; Rahmati, V.; Isstas, M.; Wutke, J.; Stark, A. W.; Franke, C.; Geis, C.; Witte, O. W.; Huebener, M.; Bolz, J.; Margrie, T. W.; Holthoff, K.; Teichert, M.
10.1101/2022.11.04.515161 — neuroscience — Posted on 2022-11-04
3507 Evaluation of antibody kinetics and durability in health subjects vaccinated with inactivated COVID-19 vaccine (CoronaVac): A cross-sectional and cohort study in Zhejiang, China
Zhang, H.; Hua, Q.; Xu, N.; Zhang, X.; Chen, B.; Ma, X.; Hu, J.; Chen, Z.; Yu, P.; Lei, H.; Wang, S.; Ding, L.; Fu, J.; Liao, Y.; Yang, J.; Jiang, J.; Lv, H.
10.1101/2022.11.03.515011 — immunology — Posted on 2022-11-04
3508 Mapping the convergence of genes for coronary artery disease onto endothelial cell programs
Schnitzler, G. R.; Kang, H.; Lee-Kim, V. S.; Ma, R. X.; Zeng, T.; Angom, R. S.; Fang, S.; Vellarikkal, S. K.; Zhou, R.; Guo, K.; Sias-Garcia, O.; Bloemendal, A.; Munson, G.; Guckelberger, P.; Nguyen, T. H.; Bergman, D. T.; Cheng, N.; Cleary, B.; Aragam, K.; Mukhopadhyay, D.; Lander, E. S.; Finucane, H. K.; Gupta, R. M.; Engreitz, J. M.
10.1101/2022.11.01.514606 — genomics — Posted on 2022-11-04
3509 A specific mesh-like organization of human septin octameric complex drives membrane reshaping and curvature sensitivity
Nakazawa, K.; Kumar, G.; Chauvin, B.; Di Cicco, A.; Pellegrino, L.; Trichet, M.; Hajj, B.; Cabral, J.; Sain, A.; Mangenot, S.; Bertin, A.
10.1101/2022.11.02.514824 — biophysics — Posted on 2022-11-04
3510 Fine-scale variability in coral bleaching and mortality during a marine heatwave
Yadav, S.; Roach, T.; McWilliam, M. J.; Caruso, C.; Rocha de Souza, M.; Foley, C.; Allen, C.; Dilworth, J.; Huckeba, J.; Santoro, E. P.; Wold, R.; Simpson, J.; Miller, S.; Hancock, J. R.; Drury, C.; Madin, J. S.
10.1101/2022.11.01.514760 — ecology — Posted on 2022-11-04
3511 Identification of NAD-RNAs and ADPR-RNA decapping in the archaeal model organisms Sulfolobus acidocaldarius and Haloferax volcanii
Gomes-Filho, J. V.; Breuer, R.; Morales-Filloy, H. G.; Pozhydaieva, N.; Borst, A.; Paczia, N.; Soppa, J.; Höfer, K.; Jäschke, A.; Randau, L.
10.1101/2022.11.02.514978 — molecular biology — Posted on 2022-11-04
3512 The conserved protein WhiA influences branched-chain fatty acid precursors in Bacillus subtilis
Hamoen, L. W.; de Sousa, J.; Bohorquez, L.; Garcia-Garcia, T.; Dugar, G.; Jonker, M. J.; Wang, B.; Noirot-Gros, M.-F.; Lalk, M.
10.1101/2022.11.02.514974 — microbiology — Posted on 2022-11-04
3513 Dual RNA-Seq profiling unveils mycoparasitic activities of Trichoderma atroviride against haploid Armillaria ostoyae in antagonistic interaction assays
Chen, L.; Champramary, S.; Sahu, N.; Indic, B.; Szucs, A.; Nagy, G.; Maroti, G.; Pap, B.; Languar, O.; Vagvölgyi, C.; Nagy, L. G.; Kredics, L.; Sipos, G.
10.1101/2022.11.02.514975 — microbiology — Posted on 2022-11-04
3514 Multi-model order spatially constrained ICA reveals highly replicable group differences and consistent predictive results from fMRI data
Meng, X.; Iraji, A.; Fu, Z.; Kochunov, P.; Belger, A.; Ford, J.; McEwen, S.; Mathalon, D. H.; Mueller, B. A.; Pearlson, G. D.; Potkin, S. G.; Preda, A.; Turner, J.; Erp, T. G. M. v.; Sui, J.; Calhoun, V.
10.1101/2022.11.02.514809 — neuroscience — Posted on 2022-11-04
3515 Dodecyl Creatine Ester Improves Cognitive Function and Identifies Drivers of Creatine Deficiency.
Mabondzo, A.; Harati, R.; Broca-Brisson, L.; Guyot, A.-C.; Costa, N.; Cacciante, F.; Putignano, E.; Baroncelli, L.; Skelton, M.; Saab, C.; Martini, E.; Benech, H.; Joudinaud, T.; Gaillard, J.-C.; Armengaud, J.; Hamoudi, R. A.
10.1101/2022.11.03.514982 — neuroscience — Posted on 2022-11-04
3516 Antiviral effect of candies containing persimmon-derived tannin against SARS-CoV-2 delta strain
Furukawa, R.; Kitabatake, M.; Ouji-Sageshima, N.; Tomita, D.; Kumamoto, M.; Suzuki, Y.; Nakano, A.; Nakano, R.; Matsumura, Y.; Kayano, S.-i.; Yano, H.; Tamaki, S.; Ito, T.
10.1101/2022.10.31.513793 — microbiology — Posted on 2022-11-04
3519 Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species
Essaidi-Laziosi, M.; Perez Rodriguez, F. J.; Alvarez, C.; Sattonnet-Roche, P.; Torriani, G.; Bekliz, M.; Adea, K.; Lenk, M.; Preiser, W.; Suliman, T.; Muller, M. A.; Drosten, C.; Kaiser, L.; Eckerle, I.
10.1101/2022.10.04.510352 — microbiology — Posted on 2022-11-04
3520 It Takes Two: Bimodal interactions between the SARS-CoV-1 fusion peptide and Ca2+ ions promote membrane insertion and viral entry
Carten, J.; Bidon, M. K.; Khelashvili, G.; Straus, M.; Tang, T.; Jaimes, J. A.; Weinstein, H.; Whittaker, G.; Daniel, S.
10.1101/2022.03.03.482731 — microbiology — Posted on 2022-11-04
3522 The effect of lysergic acid diethylamide (LSD) on whole-brain functional and effective connectivity
Bedford, P.; Hauke, D. J.; Wang, Z.; Roth, V.; Nagy-Huber, M.; Holze, F.; Ley, L.; Vizeli, P.; Liechti, M. E.; Borgwardt, S.; Müller, F.; Diaconescu, A. O.
10.1101/2022.11.01.514687 — neuroscience — Posted on 2022-11-04
3529 FLI1 and FRA1 transcription factors drive the transcriptional regulatory networks characterizing muscle invasive bladder cancer
Guneri Sozeri, P. Y.; Ozden Yilmaz, G.; Kisim, A.; Cakiroglu, E.; Eray, A.; Uzuner, H.; Karakulah, G.; Pesen Okvur, D.; Senturk, S.; Erkek Ozhan, S.
10.1101/2021.11.22.468946 — cancer biology — Posted on 2022-11-04
3530 RAPTOR: A Five-Safes approach to a secure, cloud native and serverless genomics data repository
Shih, C. C.; Chen, J.; Lee, A. S.; Bertin, N.; Hebrard, M.; Khor, C. C.; Li, Z.; Tan, J. H. J.; Meah, W. Y.; Peh, S. Q.; Mok, S. Q.; Sim, K. S.; Liu, J.; Wang, L.; Wong, E.; Li, J.; Tin, A.; Cheng, C.-Y.; Heng, C.-K.; Yuan, J.-M.; Koh, W.-P.; Saw, S. M.; Friedlander, Y.; Sim, X.; Chai, J. F.; Chong, Y. S.; Davila, S.; Goh, L. L.; Lee, E. S.; Wong, T. Y.; Karnani, N.; Leong, K. P.; Yeo, K. K.; Chambers, J. C.; Lim, S. C.; Goh, R. S. M.; Tan, P.; Dorajoo, R.
10.1101/2022.10.27.514127 — genomics — Posted on 2022-11-04
3534 Metabolic clearance rate modeling: A translational approach to quantifying cerebral metabolism using hyperpolarized pyruvate.
Grist, J. T.; Boegh, N.; Hansen, E.; Schneider, A.; Healicon, R.; Ball, V.; Miller, J.; Smart, S.; Couch, Y.; Buchan, A.; Tyler, D.; Laustsen, C.
10.1101/2022.11.02.514924 — physiology — Posted on 2022-11-04
3539 The BRCA1 isoform, BRCA1-IRIS, operates independently of the full-length BRCA1 in the Fanconi anemia pathway
Li, A. G.; Chan, B. C.; Murphy, E. C.; He, Y.; Ors, M.; Kong, Q.; Cantor, S. B.; Brugge, J. S.; Brown, M.; Livingston, D. M.
10.1101/2022.11.02.514969 — molecular biology — Posted on 2022-11-04
3541 Apoptotic contraction drives target cell release by cytotoxic T cells
Sanchez, E. E.; Tello-Lafoz, M.; Guo, A. J.; de Jesus, M.; Winer, B. Y.; Budhu, S.; Chan, E.; Rosiek, E.; Kondo, T.; Dusold, J.; Taylor, N.; Altan-Bonnet, G.; Olson, M. F.; Huse, M.
10.1101/2022.11.02.514865 — immunology — Posted on 2022-11-04
3543 Deep learning for histopathological subtyping and grading of lung adenocarcinoma
Lami, K.; Ota, N.; Yamaoka, S.; Bychkov, A.; Matsumoto, K.; Uegami, W.; Attanoos, R.; Berezowska, S.; Brcic, L.; Cavazza, A.; English, J.; Fabro, A. T.; Ishida, K.; Kashima, Y.; Kitamura, Y.; Larsen, B. T.; Marchevsky, A. M.; Miyazaki, T.; Morimoto, S.; Ozasa, M.; Roden, A. C.; Schneider, F.; Smith, M. L.; Tabata, K.; Takano, A. M.; Tomonori, T.; Tsushiya, T.; Nagayasu, T.; Sakanashi, H.; Fukuoka, J.
10.1101/2022.11.02.514811 — pathology — Posted on 2022-11-04
3547 Ras-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophy
Cuevas-Navarro, A.; Wagner, M.; Van, R.; Swain, M.; Allison, M. R.; Cheng, A.; Messing, S.; Simanshu, D. K.; Sale, M. J.; McCormick, F.; Stephen, A. G.; Castel, P.
10.1101/2022.11.02.514888 — biochemistry — Posted on 2022-11-03
3552 Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo
Melig, G.; Nobuhisa, I.; Saito, K.; Tsukahara, R.; Itabashi, A.; Kanai, Y.; Kanai-Azuma, M.; Osawa, M.; Oshima, M.; Iwama, A.; Taga, T.
10.1101/2022.11.01.513960 — developmental biology — Posted on 2022-11-03
3553 Single-cell assessment of trophoblast stem cell-based organoids as human placenta-modeling platforms
Shannon, M. J.; McNeill, G. L.; Koksal, B.; Baltayeva, J.; Wachter, J.; Castellana, B.; Penaherrera, M. S.; Robinson, W.; Leung, P. C. K.; Beristain, A. G.
10.1101/2022.11.02.514970 — developmental biology — Posted on 2022-11-03
3554 Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors
Williams, R.; Taylor, G.; Ling, I. T. C.; Candido-Ferreira, I.; Mayes, S.; Bozhilov, Y.; Tyser, R. C. V.; Srinivas, S.; Hughes, J. R.; Sauka-Spengler, T.
10.1101/2022.11.03.515045 — developmental biology — Posted on 2022-11-04
3555 Differentiation is accompanied by a progressive loss in transcriptional memory
Fourneaux, C.; Racine, L.; Koering, C.; Dussurgey, S.; Vallin, E.; Moussy, A.; Parmentier, R.; Brunard, F.; Stockholm, D.; Modolo, L.; Picard, F.; Gandrillon, O.; Paldi, A.; Gonin-Giraud, S.
10.1101/2022.11.02.514828 — cell biology — Posted on 2022-11-03
3557 A TYPE 2 INNATE LYMPHOID CELL-INTERLEUKIN 9 CIRCUIT INDUCES PANETH CELL METAPLASIA AND SMALL INTESTINAL REMODELING
Yuan, C.-Y.; Rayasam, A.; Moe, A.; Xu, W.; Szabo, A.; Hayward, M.; Wells, C.; Salzman, N.; Drobyski, W.
10.1101/2022.11.02.514603 — immunology — Posted on 2022-11-03
3558 Epigenetically distinct synaptic architecture in clonal compartments in the teleostean dorsal pallium
Isoe, Y.; Nakamura, R.; Nonaka, S.; Kamei, Y.; Okuyama, T.; Yamamoto, N.; Takeuchi, H.; Takeda, H.
10.1101/2022.10.01.510385 — neuroscience — Posted on 2022-11-03
3560 Laurdan discerns lipid membrane hydration and cholesterol content
Orlikowska-Rzeznik, H.; Krok, E.; Chattopdhyay, M.; Lester, A.; Piatkowski, L.
10.1101/2022.11.02.514927 — biophysics — Posted on 2022-11-03
3569 Low-frequency motor cortex EEG predicts four levels of rate of change of force during ankle dorsiflexion
O'Keeffe, R.; Shirazi, S. Y.; Del Vecchio, A.; Ibanez, J.; Mrachacz-Kersting, N.; Bighamian, R.; Rizzo, J.; Farina, D.; Atashzar, S. F. F.
10.1101/2022.11.02.514949 — bioengineering — Posted on 2022-11-03
3570 Epicardial reservoir-enabled multidose delivery of exogenous FSTL1 leads to improved cardiac function, healing, and angiogenesis.
Varela, C. E.; Monahan, D. S.; Islam, S.; Whyte, W.; Bonnemain, J.; Ngoy, S.; Fisch, S.; Duffy, G. P.; Roche, E. T.
10.1101/2022.11.02.513725 — bioengineering — Posted on 2022-11-03
3571 A Model of High-Speed Endovascular Sonothrombolysis with Vortex Ultrasound-Induced Shear Stress to Treat Cerebral Venous Sinus Thrombosis
Zhang, B.; Wu, H.; Kim, H.; Welch, P. J.; Cornett, A.; Stocker, G.; Nogueira, R. G.; Kim, J.; Owens, G.; Dayton, P. A.; Xu, Z.; Shi, C.; Jiang, X.
10.1101/2022.11.02.514936 — bioengineering — Posted on 2022-11-03
3572 Characterization of N distribution in different organs of winter wheat using UAV-based remote sensing
Wang, F.; Li, W.; Liu, Y.; Qin, W.; Ma, L.; Zhang, Y.; Sun, Z.; Wang, Z.; Li, F.; Yu, K.
10.1101/2022.11.02.514839 — bioengineering — Posted on 2022-11-03
3582 Overconfidence undermines global wildlife abundance trends
Johnson, T. F.; Beckerman, A. P.; Childs, D. Z.; Griffiths, C.; Capdevila, P.; Clements, C.; Besson, M.; Gregory, R.; Evans, K.; Thomas, G. H.; Delmas, E.; Webb, T.; Freckleton, R.
10.1101/2022.11.02.514877 — ecology — Posted on 2022-11-03
3583 Mechanisms of vascular maturation and maintenance captured by longitudinal imaging of live mouse skin
Kam, C. Y.; Singh, I. D.; Matte-Martone, C.; Gonzalez, D. G.; Sola, P.; Solanas, G.; Bonjoch, J.; Marsh, E. D.; Hirschi, K. K.; Greco, V.
10.1101/2022.11.02.514907 — developmental biology — Posted on 2022-11-03
3584 SUMOylation regulates Lem2 function in centromere clustering and silencing
Strachan, J.; Leidecker, O.; Spanos, C.; Le Coz, C.; Chapman, E.; Arsenijevic, A.; Zhang, H.; Zhao, N.; Bayne, E. H.
10.1101/2022.11.02.514898 — cell biology — Posted on 2022-11-03
3590 Eos promotes TH2 differentiation by propagating the IL-2/STAT5 signaling pathway.
Tuazon, J. A.; Read, K. A.; Sreekumar, B. K.; Yaeger, M. J.; Varikuti, S.; Jones, D. M.; Warren, R. T.; Powell, M. D.; Rasheed, M. N.; Duncan, E. G.; Childs, L. M.; Gowdy, K. M.; Oestreich, K. J.
10.1101/2022.11.02.514868 — immunology — Posted on 2022-11-03
3591 Single-cell transcriptomics reveals subset-specific metabolic profiles underpinning the bronchial epithelial response to flagellin
Ramirez-Moral, I.; Schuurman, A. R.; Butler, J. M.; Yu, X.; de Haan, K.; van Leeuwen, S.; de Vos, A. D.; de Jong, M. D.; Vieira Braga, F. A.; van der Poll, T.
10.1101/2022.11.02.514918 — immunology — Posted on 2022-11-03
3593 Quartet metabolite reference materials for assessing inter-laboratory reliability and data integration of metabolomic profiling
Zhang, N.; Zhang, P.; Chen, Q.; Zhou, K.; Liu, Y.; Wang, H.; Xie, Y.; Ren, L.; Hou, W.; Yang, J.; Yu, Y.; Zheng, Y.; Shi, L.
10.1101/2022.11.01.514762 — systems biology — Posted on 2022-11-03
3594 Towards universal synthetic heterotrophy using a metabolic coordinator
Sullivan, S. F.; Shetty, A.; Bharadwaj, T.; Krishna, N.; Trivedi, V. D.; Endalur Gopinarayanan, V.; Sellers, D. M.; Kumar R, P.; Nair, N. U.
10.1101/2022.11.02.514957 — synthetic biology — Posted on 2022-11-03
3595 A gene silencing screen uncovers diverse tools for targeted gene repression in Arabidopsis
Wang, M.; Zhong, Z.; Gallego-Bartolome, J.; Li, Z.; Feng, S.; Kuo, P. H.; Kan, R. L.; Richey, J.; Jami-Alahmadi, Y.; Wohlschlegel, J.; Jacobsen, S. E.
10.1101/2022.11.01.514775 — plant biology — Posted on 2022-11-03
3596 Limiting etioplast gene-expression induces apical hook twisting during skoto-morphogenesis of Arabidopsis seedlings
Sajib, S. A.; Grubler, B.; Oukacine, C.; Delannoy, E.; Courtois, F.; Mauve, C.; Lurin, C.; Gakiere, B.; Pfannschmidt, T.; Merendino, L.
10.1101/2022.11.02.514823 — plant biology — Posted on 2022-11-03
3600 Gene model correction for PVRIG in single cell and bulk sequencing data enables accurate detection and study of its functional relevance
Nemzer, S.; Sabath, N.; Wool, A.; Alteber, Z.; Ando, H.; Nickles-Fader, A.; Wang, T.-L.; Shih, I.-M.; Pardoll, D. M.; Ganguly, S.; Turpaz, Y.; Levine, Z.; Granit, R. Z.
10.1101/2022.11.02.514879 — bioinformatics — Posted on 2022-11-03
3601 An information theoretic approach to detecting spatially varying genes
Jones, D. C.; Danaher, P.; Kim, Y.; Beechem, J. M.; Gottardo, R.; Newell, E. W.
10.1101/2022.11.02.514777 — bioinformatics — Posted on 2022-11-03
3604 Characterisation of acetogen formatotrophic potential using E. limosum
Wood, J. C.; Gonzalez-Garcia, R. A.; Daygon, D.; Talbo, G.; Plan, M. R.; Marcellin, E.; Virdis, B.
10.1101/2022.11.02.514939 — bioengineering — Posted on 2022-11-03
3605 Bio-friendly long-term subcellular dynamic recording by self-supervised image enhancement microscopy
Zhang, G.; Li, X.; Zhang, Y.; Han, X.; Li, X.; Yu, J.; Liu, B.; Wu, J.; Yu, L.; Dai, Q.
10.1101/2022.11.02.514874 — bioengineering — Posted on 2022-11-03
3606 IPSILESIONAL HIPPOCAMPAL GABA CORRELATES WITH COGNITIVE IMPAIRMENT AND MALADAPTIVE NEUROGENESIS AFTER STROKE IN MICE
Torres-Lopez, C.; Cuartero, M. I.; Garcia-Culebras, A.; De La Parra, J.; Fernandez-Valle, M. E.; Benito, M.; Vazquez-Reyes, S.; Jareno-Flores, T.; Hurtado, O.; Buckwalter, M. S.; Garcia-Segura, J. M.; Lizasoain, I.; Moro, M. A.
10.1101/2022.11.02.514653 — animal behavior and cognition — Posted on 2022-11-03
3607 The fine-scale recombination rate variation and associations with genomic features in a butterfly
Palahi i Torres, A.; Höök, L.; Näsvall, K.; Shipilina, D.; Wiklund, C.; Vila, R.; Pruisscher, P.; Backström, N.
10.1101/2022.11.02.514807 — genomics — Posted on 2022-11-03
3609 Single-cell multi-omics decodes regulatory programs during development of mouse secondary palate
Yan, F.; Suzuki, A.; Iwaya, C.; Pei, G.; Chen, X.; Yoshioka, H.; Yu, M.; Simon, L. M.; Iwata, J.; Zhao, Z.
10.1101/2022.11.02.514609 — developmental biology — Posted on 2022-11-03
3613 Disruption of HIF1A translational control attenuates the HIF-dependent hypoxic response and solid tumour formation in vivo
Hunter, J. E.; McHugh, O.; Ecclestone, G. B.; Child, F.; Mearns, H.; Robson, G.; Dadzie, M.; Rocha, S.; Perkins, N. D.; Kenneth, N. S.
10.1101/2022.11.02.514731 — cancer biology — Posted on 2022-11-03
3614 MULTISCALE ANALYSIS AND VALIDATION OF EFFECTIVE DRUG COMBINATIONS TARGETING DRIVER KRAS MUTATIONS IN NON-SMALL CELL LUNG CANCER
BRUGGEMANN, L.; Falls, Z.; Mangione, W.; Schwartz, S. A.; Battaglia, S.; Aalinkeel, R.; Mahajan, S. D.; Samudrala, R.
10.1101/2022.09.21.508953 — bioinformatics — Posted on 2022-11-03
3615 CineFinch: An animated female zebra finch for studying courtship interactions
Phaniraj, N.; Joshi, S.; Trimbake, P.; Pujari, A.; Ramadurai, S.; Kalra, S.; Ratnaparkhi, N.; Rajan, R.
10.1101/2022.11.02.514933 — animal behavior and cognition — Posted on 2022-11-03
3617 A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency
Hsieh, E.; Janssens, D. H.; Paddison, P. J.; Browne, E. P.; Henikoff, S.; Ohainle, M.; Emerman, M.
10.1101/2022.08.23.504195 — microbiology — Posted on 2022-11-03
3618 Artificial Gravity During a Spaceflight Analog Alters Brain Sensory Connectivity
McGregor, H. R.; Lee, J. K.; Mulder, E. R.; De Dios, Y. E.; Beltran, N. E.; Wood, S. J.; Bloomberg, J. J.; Mulavara, A. P.; Seidler, R. D.
10.1101/2022.11.02.514887 — neuroscience — Posted on 2022-11-03
3622 Development and validation of an fMRI-informed EEG model of reward-related ventral striatum activation
Singer, N.; Poker, G.; Dunsky, N.; Nemni, S.; Doron, M.; Baker, T.; Dagher, A.; Zatorre, R.; Hendler, T.
10.1101/2022.11.01.514407 — neuroscience — Posted on 2022-11-03
3625 The molecular genetic landscape of human brain size variation
Seidlitz, J.; Mallard, T. T.; Vogel, J. W.; Lee, Y. H.; Warrier, V.; Ball, G.; Hansson, O.; Hernandez, L. M.; Mandal, A. S.; Wagstyl, K.; Lombardo, M. V.; Courchesne, E.; Glessner, J. T.; Satterthwaite, T. D.; Bethlehem, R. A. I.; Lifespan Brain Chart Consortium, ; Tasaki, S.; Ng, B.; Gaiteri, C.; Smoller, J. W.; Ge, T.; Gandal, M. J.; Alexander-Bloch, A. F.
10.1101/2022.11.03.514996 — neuroscience — Posted on 2022-11-03
3626 Astrocytes regulate spatial memory in a sex-specific manner
Meadows, S. M.; Palaguachi, F.; Licht-Murava, A.; Barnett, D.; Zimmer, T. S.; Zhou, C.; McDonough, S. R.; Orr, A. L.; Orr, A. G.
10.1101/2022.11.03.511881 — neuroscience — Posted on 2022-11-03
3627 Beta band rhythms influence reaction times
Rassi, E.; Lin, W. M.; Zhang, Y.; Emmerzaal, J.; Haegens, S.
10.1101/2022.11.03.515019 — neuroscience — Posted on 2022-11-03
3628 Munc13 and SNAP25 dependent tethering plays a key role in synaptic vesicle priming
Papantoniou, C.; Laugks, U.; Betzin, J.; Capitanio, C.; Ferrero, J. J.; Sanchez-Prieto, J.; Schoch, S.; Brose, N.; Baumeister, W.; Cooper, B. H.; Imig, C.; Lucic, V.
10.1101/2022.04.10.487799 — neuroscience — Posted on 2022-11-03
3629 Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later.
Attaheri, A.; Ni Choisdealbha, A.; Rocha, S.; Brusini, P.; Di Liberto, G. M.; Mead, N.; Olawole-Scott, H.; Boutris, P.; Gibbon, S.; Williams, I.; Grey, C.; Alfaro e Oliveira, M.; Brough, C.; Flanagan, S.; Goswami, U.
10.1101/2022.11.02.514963 — neuroscience — Posted on 2022-11-03
3633 High resolution mapping of the breast cancer tumor microenvironment using integrated single cell, spatial and in situ analysis of FFPE tissue
Janesick, A.; Shelansky, R.; Gottscho, A.; Wagner, F.; Rouault, M.; Beliakoff, G.; Faria de Oliveira, M.; Kohlway, A.; Abousoud, J.; Morrison, C.; Drennon, T. Y.; Mohabbat, S.; Williams, S.; 10x Development Teams, ; Taylor, S.
10.1101/2022.10.06.510405 — cancer biology — Posted on 2022-11-03
3634 JINXED: Just in time crystallization for easy structure determination of biological macromolecules
Henkel, A.; Galchenkova, M.; Maracke, J.; Yefanov, O.; Hakanpaeae, J.; Mesters, J. R.; Chapman, H. N.; Oberthuer, D.
10.1101/2022.10.26.513656 — biophysics — Posted on 2022-11-03
3637 Loss of altruism in the social amoeba Dictyostelium discoideum is associated with the G protein-coupled receptor grlG
Walker, L. M.; Sherpa, R. N.; Ivaturi, S.; Brock, D. A.; Walker, J. R.; Strassmann, J. E.; Queller, D. C.
10.1101/2022.10.21.513250 — evolutionary biology — Posted on 2022-11-03
3639 Accurate tropical forest individual tree crown delineation from RGB imagery using Mask R-CNN
Ball, J. G. C.; Hickman, S. H. M.; Jackson, T. D.; Koay, X. J.; Hirst, J.; Jay, W.; Aubry-Kientz, M.; Vincent, G.; Coomes, D. A.
10.1101/2022.07.10.499480 — ecology — Posted on 2022-11-03
3641 Two Competing Guilds as a Core Microbiome Signature for Health Recovery
Wu, G.; Xu, T.; Zhao, N.; Lam, Y. Y.; Ding, X.; Wei, D.; Fan, J.; Shi, Y.; Li, X.; Li, M.; Ji, S.; Wang, X.; Fu, H.; Zhang, F.; Peng, Y.; Shi, Y.; Zhang, C.; Zhao, L.
10.1101/2022.05.02.490290 — microbiology — Posted on 2022-11-03
3642 CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy
Sharp, C.; Thompson, B. H.; Nash, T. J.; Lee, O.; Pinto, R. M.; Thorley, L.; Lin, Y.-T.; Sives, S.; Wise, H.; Clohisey, S. M. R.; Grey, F.; Vervelde, L.; Simmonds, P.; Digard, P.; Gaunt, E. R.
10.1101/2022.04.29.490024 — microbiology — Posted on 2022-11-03
3647 Shadow imaging for panoptical visualisation of living brain tissue
Dembitskaya, Y.; Boyce, A. K. J.; Idziak, A.; Pourkhalili Langeroudi, A.; Le Bourdelles, G.; Girard, J.; Arizono, M.; Ducros, M.; Sato-Fitoussi, M.; Ochoa de Amezaga, A.; Oizel, K.; Bancelin, S.; Mercier, L.; Pfeiffer, T.; Thompson, R. J.; Kim, S. K.; Bikfalvi, A.; Nagerl, V.
10.1101/2022.11.03.511028 — neuroscience — Posted on 2022-11-03
3650 A permissive role for dopamine in the production of vigorous movements
Liu, H.; Melani, R.; Sankaramanchi, A.; Zeng, R.; Maltese, M.; Martin, J. R.; Tritsch, N. X.
10.1101/2022.11.03.514328 — neuroscience — Posted on 2022-11-03
3651 Imaging the Neural Substrate of Trigeminal Neuralgia Pain Using Deep Learning
liang, y.; zhao, q.; Hu, Z.; Bo, K.; Meyyappan, S.; Neubert, J.; Ding, M.
10.1101/2022.11.02.514527 — neuroscience — Posted on 2022-11-03
3655 Parabolic avalanche scaling in the synchronization of cortical cell assemblies
Capek, E.; Lins-Ribeiro, T.; Srinivasan, K.; Miller, S. R.; Victor, M.; Geist, E.; Vakili, A.; Pajevic, S.; Chialvo, D. R.; Plenz, D.
10.1101/2022.11.02.514938 — neuroscience — Posted on 2022-11-03
3656 HB-EGF and zinc activate EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures
Pastor-Alonso, O.; Dura, I.; Bernardo-Castro, S.; Varea, E.; Muro-Garcia, T.; Martin-Suarez, S.; Encinas-Perez, J. M.; Pineda, J. R.
10.1101/2022.11.02.514820 — neuroscience — Posted on 2022-11-03
3659 5-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in mice
Jefferson, S. J.; Gregg, I.; Dibbs, M.; Liao, C.; Wu, H.; Davoudian, P. A.; Sprouse, J. S.; Sherwood, A. M.; Kaye, A. P.; Pittenger, C.; Kwan, A. C.
10.1101/2022.11.03.515044 — neuroscience — Posted on 2022-11-03
3660 Learning low-dimensional generalizable naturalfeatures from retina using a U-net
Wang, S.; Hoshal, B.; de Laittre, E.; Marre, O.; Berry, M. J.; Palmer, S.
10.1101/2022.11.02.514893 — neuroscience — Posted on 2022-11-03
3665 DIFFERENTIAL MEMORY IMPAIRMENT ACROSS RELATIONAL DOMAINS IN TEMPORAL LOBE EPILEPSY
Tavakol, S.; Kebets, V.; Royer, J.; Li, Q.; Auer, H.; DeKraker, J.; Jefferies, E.; Bernasconi, N.; Bernasconi, A.; Helmstaedter, C.; Caciagli, L.; Frauscher, B.; Smallwood, J.; Bernhardt, B.
10.1101/2022.11.01.514752 — neuroscience — Posted on 2022-11-03
3667 Spatial cell type mapping of multiple sclerosis lesions
Lerma-Martin, C.; Badia-i-Mompel, P.; Ramirez Flores, R. O.; Sekol, P.; Hofmann, A.; Thaewel, T.; Riedl, C. J.; Wuennemann, F.; Ibarra-Arellano, M. A.; Trobisch, T.; Eisele, P.; Schapiro, D.; Haeussler, M.; Hametner, S.; Saez-Rodriguez, J.; Schirmer, L.
10.1101/2022.11.03.514906 — neuroscience — Posted on 2022-11-03
3668 Independent component analysis reveals an early hippocampal recognition system using intracerebral evoked potentials in humans
Lopez-Madrona, V. J.; Trebuchon, A.; Mindruta, I.; Barbeau, E. J.; Barborica, A.; Pistol, C.; Oane, I.; ALARIO, F.- X.; Benar, C. G.
10.1101/2022.11.02.513525 — neuroscience — Posted on 2022-11-03
3669 Preservation of thalamocortical circuitry is essential for good recovery in comatose survivors of cardiac arrest
Tewarie, P. K.; Tjepkema-Cloostermans, M. C.; Abeysuriya, R. G.; Hofmeijer, J.; van Putten, M. J. A. M.
10.1101/2022.11.02.514844 — neuroscience — Posted on 2022-11-03
3671 Effect of selective lesions of nucleus accumbens μ-opioid receptor-expressing cells on heroin self-administration in male and female rats: a study with novel Oprm1-Cre knock-in rats
Bossert, J. M.; Mejias-Aponte, C. A.; Saunders, T. L.; Altidor, L. K.-P.; Emery, M. A.; Fredriksson, I.; Batista, A.; Claypool, S. M.; Caldwell, K. E.; Reiner, D. J.; Chow, J. J.; Foltz, M.; Kumar, V.; Seasholtz, A.; Hughes, E. D.; Filipiak, W. E.; Harvey, B. K.; Richie, C. T.; Vautier, F.; Gomez, J. L.; Michaelides, M.; Kieffer, B. L.; Watson, S. J.; Akil, H.; Shaham, Y.
10.1101/2022.11.02.514895 — neuroscience — Posted on 2022-11-03
3673 Regulation of human trophoblast gene expression by endogenous retroviruses
Frost, J. M.; Amante, S. M.; Okae, H.; Jones, E. M.; Ashley, B.; Lewis, R. M.; Cleal, J. K.; Caley, M. P.; Arima, T.; Maffucci, T.; Branco, M. R.
10.1101/2022.04.26.489485 — genetics — Posted on 2022-11-03
3674 Molecular Mechanism for Bacterial Degradation of Plant Hormone Auxin
Ma, Y.; Li, X.; Wang, F.; Zhang, L.; Che, X.; Yu, D.; Liu, X.; Li, Z.; Sun, H.; Yu, G.; Zhang, H.
10.1101/2022.11.01.514793 — microbiology — Posted on 2022-11-03
3675 Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation
Lemerle, E.; Laine, J.; Moulay, G.; Bigot, A.; Labasse, C.; Madelaine, A.; Canette, A.; Aubin, P.; Vallat, J.-M.; Romero, N. B.; Bitoun, M.; Mouly, V.; Isabelle, M.; Cadot, B.; Picas, L.; Vassilopoulos, S.
10.1101/2022.11.01.514746 — cell biology — Posted on 2022-11-03
3678 Towards increased accuracy and reproducibility in SARS-CoV-2 next generation sequence analysis for public health surveillance
Connor, R.; Yarmosh, D. A.; Maier, W.; Shakya, M.; Martin, R.; Bradford, R.; Brister, J. R.; Chain, P. S.; Copeland, C. A.; di Iulio, J.; Ebert, P.; Jin, Y.; Gutni, J.; Katz, K. S.; Kochergin, A.; LaRosa, T.; Li, J.; Li, P.-E.; Lo, C.-c.; Rashid, S.; Svarovskaia, E. S.; Xiao, C.; Zalunin, V.; Pruitt, K. D.
10.1101/2022.11.03.515010 — bioinformatics — Posted on 2022-11-03
3682 Human FcγRIIIa activation on splenic macrophages drives the in vivo pathogenesis of dengue disease
Yamin, R.; Kao, K. S.; MacDonald, M. R.; Cantaert, T.; Rice, C. M.; Ravetch, J. V.; Bournazos, S.
10.1101/2022.11.02.514909 — immunology — Posted on 2022-11-03
3683 G protein-biased LPAR1 agonism promotes prototypic antidepressant effects
Kajitani, N.; Okada-Tsucioka, M.; Inoue, A.; Miyano, K.; Masuda, T.; Boku, S.; Iwamoto, K.; Ohtsuki, S.; Uezono, Y.; Aoki, J.; Takebayashi, M.
10.1101/2022.11.02.514841 — neuroscience — Posted on 2022-11-03
3684 A land plant specific VPS13 mediates polarized vesicle trafficking in germinating pollen
Tangpranomkorn, S.; Igarashi, M.; Ishizuna, F.; Kato, Y.; Suzuki, T.; Fujii, S.; Takayama, S.
10.1101/2022.11.01.514778 — plant biology — Posted on 2022-11-03
3685 MORC proteins regulate transcription factor binding by mediating chromatin compaction in active chromatin regions
Zhong, Z.; Xue, Y.; Harris, C. J.; Wang, M.; Li, Z.; Ke, Y.; Jami-Alahmadi, Y.; Feng, S.; Wohlschlegel, J. A.; Jacobsen, S. E.
10.1101/2022.11.01.514783 — plant biology — Posted on 2022-11-03
3687 Phase-separating pyrenoid proteins form complexes in the dilute phase
He, G.; GrandPre, T.; Wilson, H.; Zhang, Y.; Jonikas, M. C.; Wingreen, N. S.; Wang, Q.
10.1101/2022.11.01.514800 — biophysics — Posted on 2022-11-03
3688 Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B
Mehlman, T. S.; Biel, J. T.; Azeem, S. M.; Nelson, E. R.; Hossain, S.; Dunnett, L. E.; Paterson, N. G.; Douangamath, A.; Talon, R.; Axford, D.; Orins, H.; von Delft, F.; Keedy, D. A.
10.1101/2022.11.02.514751 — biophysics — Posted on 2022-11-03
3690 Multiplexed neuropeptide mapping in ant brains integrating microtomography and 3D mass spectrometry imaging
Geier, B. G.; Gil Mansilla, E.; Liutkeviciute, Z.; Hellinger, R.; Vanden Broeck, J.; Oetjen, J.; Liebeke, M.; Gruber, C. W.
10.1101/2022.11.02.514707 — biophysics — Posted on 2022-11-03
3692 Metals and metal isotopes in insect wings: Implications for diet, geolocation and pollution exposure
Reich, M. S.; Kindra, M.; Dargent, F.; Hu, L.; Flockhart, D. T. T.; Norris, D. R.; Kharouba, H.; Talavera, G.; Bataille, C. P.
10.1101/2022.11.02.514901 — ecology — Posted on 2022-11-03
3694 The gradient model of brain organization in decisions involving 'empathy for pain'
Labek, K.; Sittenberger, E.; Kienhoefer, V.; Rabl, L.; Messina, I.; Schurz, M.; Stingl, J. C.; Viviani, R.
10.1101/2021.11.28.470235 — neuroscience — Posted on 2022-11-03
3696 The Circadian Clock is Disrupted in Pancreatic Cancer
Schwartz, P. B.; Nukaya, M.; Berres, M.; Rubinstein, C. D.; Wu, G.; Hogenesch, J.; Bradfield, C.; Ronnekleiv-Kelly, S.
10.1101/2022.11.01.514735 — cancer biology — Posted on 2022-11-03
3700 Adipose triglyceride lipase is regulated by CAMKK2-AMPK signaling and drives advanced prostate cancer
Awad, D.; Pulliam, T. L.; Spradlin, M. L.; Cao, P. H.-A.; Subramani, E.; Tellman, T. V.; Ribeiro, C. F.; Pakula, H.; Ackroyd, J. J.; Murray, M. M.; Han, J. J.; Piyarathna, B.; Drake, J. M.; Ittmann, M. M.; Coarfa, C.; Farach-Carson, M. C.; Loda, M.; Eberlin, L. S.; Frigo, D. E.
10.1101/2022.11.02.514910 — cancer biology — Posted on 2022-11-03
3701 Triggered Release from Thermosensitive Liposomes Improves Tumor Targeting of Vinorelbine
Regenold, M.; Kaneko, K.; Wang, X.; Peng, H. B.; Evans, J. C.; Bannigan, P.; Allen, C.
10.1101/2022.11.02.514937 — cancer biology — Posted on 2022-11-03
3703 Disruption of HIF1A translational control attenuates the HIF-dependent hypoxic response and solid tumour formation in vivo
Hunter, J. E.; McHugh, O.; Ecclestone, G. B.; Child, F.; Mearns, H.; Robson, G.; Dadzie, M.; Rocha, S.; Perkins, N. D.; Kenneth, N. S.
10.1101/2022.11.02.514731 — cancer biology — Posted on 2022-11-03
3705 Combination of Volasertib and Rapamycin Inhibits the Regrowth of TSC2-Deficient Tumors
Valianou, M.; Zhang, E. Y.; Johnson, D. L.; Meyers, R.; Markiewski, M. M.; Karbowniczek, M.; Pfeffer, L. M.; Yu, J. J.; Bissler, J. J.; Astrinidis, A.
10.1101/2022.11.02.512640 — cancer biology — Posted on 2022-11-03
3711 Diel fluctuations in in-vivo SnRK1 activity in Arabidopsis rosettes during light-dark cycles
Avidan, O.; Alexandre Moraes, T.; Mengin, V.; Feil, R.; Rolland, F. A.; Stitt, M.; Lunn, J. E.
10.1101/2022.09.23.509272 — plant biology — Posted on 2022-11-03
3713 The neuropeptidergic connectome of C. elegans
Ripoll-Sanchez, L.; Watteyne, J.; Sun, H.; Fernandez, R.; Taylor, S.; Weinreb, A.; Hammarlund, M.; Miller, D. M.; Hobert, O.; Beets, I.; Vertes, P. E.; Schafer, W. R.
10.1101/2022.10.30.514396 — neuroscience — Posted on 2022-11-03
3715 Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-causing mutations
Hussein, Y.; Tripathi, U.; Choudhary, A.; Nayak, R.; Peles, D.; Rosh, I.; Djamus, J.; Spiegel, R.; Garin-Shkolnik, T.; Stern, S.
10.1101/2022.11.02.514882 — neuroscience — Posted on 2022-11-03
3716 A new gene encoding a cytosolic glutamine synthetase in pine is linked to developing tissues
Valderrama-Martin, J. M.; Ortigosa, F.; Aledo, J. C.; Avila, C.; Canovas, F. M.; Canas, R. A.
10.1101/2022.10.27.514046 — plant biology — Posted on 2022-11-03
3717 Using evolutionary constraint to define novel candidate driver genes in medulloblastoma
Roy, A.; Sakthikumar, S.; Kozyrev, S. V.; Nordin, J.; Pensch, R.; Pettersson, M. E.; Karlsson, E.; Lindblad-Toh, K.; Forsberg-Nilsson, K.
10.1101/2022.11.02.514465 — cancer biology — Posted on 2022-11-03
3718 Determinants of sugar-induced influx in the mammalian fructose transporter GLUT5
McComas, S.; Reichenbach, T.; Mitrovic, D.; Alleva, C.; Bonaccorsi, M.; Delemotte, L.; Drew, D.
10.1101/2022.06.17.495601 — biophysics — Posted on 2022-11-03
3722 Integration of metabolism and regulation reveals rapid adaptability to growth on non-native substrates.
Trivedi, V. D.; Sullivan, S. F.; Choudhury, D.; Endalur Gopinarayanan, V.; Hart, T.; Nair, N. U.
10.1101/2022.05.21.492926 — synthetic biology — Posted on 2022-11-02
3726 Distinct Wolbachia localization patterns in oocytes of diverse host species reveal multiple strategies of maternal transmission
Radousky, Y. A.; Hague, M. T. J.; Fowler, S.; Paneru, E.; Codina, A.; Rugamas, C.; Hartzog, G.; Cooper, B. S.; Sullivan, W.
10.1101/2022.10.28.514302 — cell biology — Posted on 2022-11-02
3728 Multimodal profiling of term human decidua reveals tissue-specific immune adaptations with maternal obesity
Sureshchandra, S.; Doratt, B. M.; Mendoza, N.; Rincon, M.; Marshall, N. E.; Messaoudi, I.
10.1101/2022.11.01.514598 — immunology — Posted on 2022-11-02
3729 Dissociating Language and Thought in Human Reasoning
Coetzee, J. P.; Johnson, M. A.; Lee, Y.; Wu, A. D.; Iacoboni, M.; Monti, M.
10.1101/336123 — neuroscience — Posted on 2022-11-02
3730 Identifying cross-lineage dependencies of cell-type specific regulators in gastruloids
Braccioli, L.; van den Brand, T.; Saiz, N. A.; Fountas, C.; Celie, P. H.; Kazokaite-Adomaitiene, J.; de Wit, E.
10.1101/2022.11.01.514697 — systems biology — Posted on 2022-11-02
3731 Tomato geranylgeranyl diphosphate synthase isoform 1 specifically interacts with phytoene synthase isoform 3 to produce strigolactones in tomato roots.
Ezquerro, M.; Li, C.; Barja, M. V.; Burbano, E.; Perez-Perez, J.; Wang, Y.; Dong, L.; Lison, P.; Lopez-Gresa, M. P.; Bouwmeester, H.; Rodriguez-Concepcion, M.
10.1101/2022.11.01.514744 — plant biology — Posted on 2022-11-02
3732 Feasibility of intranasal delivery of thin-film freeze-dried, mucoadhesive AS01B-adjuvanted vaccine powders
Yu, Y.-S.; AboulFotouh, K.; Williams, G.; Suman, J.; Cano, C.; Warnken, Z. N.; Williams, R. O.; Cui, Z.
10.1101/2022.11.01.514748 — pharmacology and toxicology — Posted on 2022-11-02
3734 Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
Graziano, V.; Dannhorn, A.; Hulme, H.; Williamson, K.; Buckley, H.; Karim, S. A.; Lee, S. Y.; Kaistha, B. P.; Islam, S.; Thaventhiran, J. E. D.; Richards, F. M.; Goodwin, R.; Brais, R.; Morton, J. P.; Dovedi, S. J.; Schuller, A. G.; Eyles, J.; Jodrell, D. I.
10.1101/2022.05.24.493238 — cancer biology — Posted on 2022-11-02
3735 Characterization of a novel estrogen- and progesterone-responsive endometrial cancer cell line: HCI-EC-23
Rush, C. M.; Blanchard, Z.; Polaski, J. T.; Osborne, K. S.; Osby, K.; Vahrenkamp, J. M.; Yang, C.-H.; Lum, D. H.; Hagan, C. R.; Leslie, K. K.; Pufall, M. A.; Thiel, K. W.; Gertz, J.
10.1101/2022.08.25.505203 — cancer biology — Posted on 2022-11-02
3736 FkpA Enhances Membrane Protein Folding using an Extensive Interaction Surface
Devlin, T.; Marx, D. C.; Roskopf, M. A.; Bubb, Q. R.; Plummer, A. M.; Fleming, K. G.
10.1101/2022.11.01.514694 — biophysics — Posted on 2022-11-02
3737 Observation of a single protein by ultrafast X-ray diffraction
Ekeberg, T.; Assalauova, D.; Bielecki, J.; Boll, R.; Daurer, B. J.; Eichacker, L. A.; Franken, L. E.; Galli, D. E.; Gelisio, L.; Gumprecht, L.; Gunn, L. H.; Hajdu, J.; Hartmann, R.; Hasse, D.; Ignatenko, A.; Koliyadu, J.; Kulyk, O.; Kurta, R.; Kuster, M.; Lugmayr, W.; Lübke, J.; Mancuso, A. P.; Mazza, T.; Nettelblad, C.; Ovcharenko, Y.; Rivas, D. E.; Samanta, A. K.; Schmidt, P.; Sobolev, E.; Timneanu, N.; Usenko, S.; Westphal, D.; Wollweber, T.; Worbs, L.; Xavier, P. L.; Yousef, H.; Ayyer, K.; Chapman, H. N.; Sellberg, J. A.; Seuring, C.; Vartanyants, I. A.; Küpper, J.; Meyer, M.; Maia, F. R
10.1101/2022.03.09.483477 — biophysics — Posted on 2022-11-02
3739 A microwell platform for high-throughput longitudinal phenotyping and selective retrieval of organoids
Sockell, A.; Wong, W.; Longwell, S.; Vu, T.; Karlsson, K.; Mokhtari, D. A.; Schaepe, J.; Lo, Y.-H.; Cornelius, V.; Kuo, C.; Van Valen, D. A.; Curtis, C.; Fordyce, P. M.
10.1101/2022.11.01.514733 — bioengineering — Posted on 2022-11-02
3742 Multispecies autocatalytic RNA reaction networks in coacervates
Ameta, S.; Kumar, M.; Chakraborty, N.; Matsubara, Y. J.; S, P.; Gandavadi, D.; Thutupalli, S.
10.1101/2022.11.01.514660 — evolutionary biology — Posted on 2022-11-02
3746 Multilevel human secondary lymphoid immune system compartmentalization revealed by complementary multiplexing and mass spectrometry imaging approaches
Oyler, B. L.; Valencia-Davila, J. A.; Moysi, E.; Molyvdas, A.; Ioannidou, K.; March, K.; Ambrozak, D.; DeLeval, L.; Fabozzi, G.; Woods, A. S.; Koup, R. A.; Petrovas, C.
10.1101/2022.11.01.514691 — immunology — Posted on 2022-11-02
3747 Multi-scale structural alterations of basal ganglia in focal epilepsy as demonstrated by 7T MRI
Haast, R. A.; Testud, B.; Makhalova, J.; Dary, H.; Cabane, A.; Le Troter, A.; Ranjeva, J.-P.; Bartolomei, F.; Guye, M.
10.1101/2022.11.01.514655 — neuroscience — Posted on 2022-11-02
3751 Integrated Multi-Omics Analysis of Brain Aging in Female Nonhuman Primates Reveals Altered Signaling Pathways Relevant to Age-Related Disorders
Cox, L. A.; Puppala, S.; Chan, J.; Zimmerman, K.; Hamid, Z.; Ampong, I.; Huber, H. F.; Li, G.; Jadhav, A. Y.; Wang, B.; Li, C.; Shively, C.; Clarke, G.; Register, T. C.; Nathanielsz, P. W.; Olivier, M.
10.1101/2022.11.01.514742 — systems biology — Posted on 2022-11-02
3752 Dispersal and Plant Arrangement Condition the Timing and Magnitude of Coffee Rust Infection
Van Cauwelaert, E. M.; Gonzalez, C. G.; Boyer, D.; Hajian-Forooshani, Z.; Vandermeer, J.; Benitez, M.
10.1101/2022.04.07.487552 — systems biology — Posted on 2022-11-02
3757 Endoplasmic reticulum calnexins participate in the primary root growth response to phosphate deficiency
Montpetit, J.; Clua, J.; Hsieh, Y.-F.; Vogiatzaki, E.; Mueller, J.; Abel, S.; Strasser, R.; Poirier, Y.
10.1101/2022.11.01.514754 — plant biology — Posted on 2022-11-02
3759 Dynamic growth re-orientation orchestrates flatness in the Arabidopsis leaf
Harline, K.; Fruleux, A.; Lane, B.; Mosca, G.; Strauss, S.; Tavakolian, N.; Satterlee, J. W.; Li, C.-B.; Singh, A.; Smith, R. S.; Boudaoud, A. S.; Roeder, A. H. K.
10.1101/2022.11.01.514736 — plant biology — Posted on 2022-11-02
3760 Inhibition of the BMP pathway suppresses tumor growth via downregulation of EGFR in MEK/ERK-dependent colorectal cancer
Shimizu, S.; Kondo, J.; Onuma, K.; Ota, K.; Kamada, M.; Harada, Y.; Tanaka, Y.; Adachi Nakazawa, M.; Tamada, Y.; Okuno, Y.; Kawada, K.; Obama, K.; Coffey, R. J.; Fujiwara, Y.; Inoue, M.
10.1101/2022.11.01.514643 — cancer biology — Posted on 2022-11-02
3761 The Circadian Clock is Disrupted in Pancreatic Cancer
Schwartz, P. B.; Nukaya, M.; Berres, M.; Rubinstein, C. D.; Wu, G.; Hogenesch, J.; Bradfield, C.; Ronnekleiv-Kelly, S.
10.1101/2022.11.01.514735 — cancer biology — Posted on 2022-11-02
3762 Photocontrolled Release of Nitric Oxide for Precise Management of NO Concentration in a Solution
Zhermolenko, E. O.; Karogodina, T. Y.; Vorobev, A. Y.; Panfilov, M. A.; Moskalensky, A. E.
10.1101/2022.11.01.514656 — biophysics — Posted on 2022-11-02
3769 cLD: Rare-variant disequilibrium between genomic regions identifies novel genomic interactions
Wang, D.; He, J.; Perera, D.; Cao, C.; Kossinna, P.; Li, Q.; Zhang, W.; Alexander, P.; Wu, J.; Zhang, Q.
10.1101/2022.02.16.480745 — bioinformatics — Posted on 2022-11-02
3772 Cytotoxicity, Mutagenicity and Genotoxicity of Electronic Cigarettes Emission Aerosols Compared to Cigarette Smoke: the REPLICA project
Emma, R.; Fuochi, V.; Distefano, A.; Rust, S.; Zadjali, F.; Tobi, M. A.; Zadjali, R.; Alharthi, Z.; Pulvirenti, R.; Furneri, P. M.; Polosa, R.; Caruso, M.; Li Volti, G.
10.1101/2022.10.28.514205 — biochemistry — Posted on 2022-11-02
3776 A generalizable epigenetic clock captures aging in two nonhuman primates.
Goldman, E. A.; Watowich, M. M.; Chiou, K. L.; Mercer, A.; Sams, S. N.; Horvath, J. E.; Anderson, J.; Cayo Biobank Research Unit, ; Tung, J.; Higham, J. P.; Brent, L. J.; Martinez, M. I.; Montague, M. J.; Platt, M. L.; Sterner, K. N.; Snyder-Mackler, N.
10.1101/2022.11.01.514719 — evolutionary biology — Posted on 2022-11-02
3778 Consumer feces impact coral health in guild-specific ways
Grupstra, C. G. B.; Howe-Kerr, L. I.; van der Meulen, J. A.; Veglia, A. J.; Coy, S. R.; Correa, A.
10.1101/2022.10.31.514626 — ecology — Posted on 2022-11-02
3781 Selecting coral species for reef restoration
Madin, J.; McWilliam, M.; Quigley, K.; Bay, L.; Bellwood, D.; Doropoulos, C.; Fernandes, L.; Harrison, P.; Hoey, A.; Mumby, P.; Richards, Z.; Riginos, C.; Schiettekatte, N.; Suggett, D.; van Oppen, M.
10.1101/2021.11.03.467181 — ecology — Posted on 2022-11-02
3782 Global terrestrial nitrogen uptake and nitrogen use efficiency
Peng, Y.; Prentice, I. C.; Bloomfield, K. J.; Campioli, M.; Guo, Z.; Sun, Y.; Tian, D.; Wang, X.; Vicca, S.; Stocker, B. D.
10.1101/2022.11.01.514661 — ecology — Posted on 2022-11-02
3783 Incorporating space in hierarchical capture mark recapture models: can we better capture variance?
Van der Drift, A.-M. R.; Leirs, H.; Mariën, J.; Sabuni, C.; Mulungu, L.; Kirkpatrick, L.
10.1101/2022.11.01.514665 — ecology — Posted on 2022-11-02
3784 Foxa2 lineage+ mesendoderm forms a competitive pulmonary mesenchyme niche crucial for generating the entire lungs
Miura, A.; Sarmah, H.; Tanaka, J.; Hwang, Y.; Sawada, A.; Shimamura, Y.; Fang, Y.; Shimizu, D.; Ninish, Z.; Suer, J. L.; Dubois, N.; Davis, J.; Toyooka, S.; Wu, J.; Que, J.; Hawkins, F. J.; Lin, C.-S.; Mori, M.
10.1101/2022.10.31.514628 — developmental biology — Posted on 2022-11-02
3786 Genomic Characterization of Rare Earth Binding by Shewanella oneidensis
Medin, S.; Schmitz, A. M.; Pian, B.; Mini, K.; Reid, M. C.; Holycross, M.; Gazel, E.; Wu, M.; Barstow, B.
10.1101/2022.10.31.514631 — systems biology — Posted on 2022-11-02
3787 Targeting BET Proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
Letson, C.; Balasis, M. E.; Newman, H.; Binder, M.; Vedder, A.; Kinose, F.; Ball, M.; Kruer, T.; Quintana, A.; Lasho, T. L.; Finke, C. M.; Almada, L. L.; Grants, J. M.; Zhang, G.; Fernandez-Zapico, M. E.; Gaspar-Maia, A. E.; Lancet, J.; Komrokji, R.; Haura, E.; Reuther, G. W.; Karsan, A.; Rix, U.; Patnaik, M. M.; Padron, E.
10.1101/2022.11.01.514753 — cancer biology — Posted on 2022-11-02
3788 Molecular determinants of fibrillation in a viral amyloidogenic domain from combined biochemical and biophysical studies
Nilsson, J. F.; Baroudi, H.; Gondelaud, F.; Pesce, G.; Bignon, C.; Ptchelkine, D.; Chamieh, J.; Cottet, H.; Kajava, A. V.; Longhi, S.
10.1101/2022.11.02.514851 — biochemistry — Posted on 2022-11-02
3789 Variation in histone configurations correlates with gene expression across nine inbred strains of mice
Tyler, A. L.; Spruce, C.; Kursawe, R.; Haber, A.; Ball, R. L.; Pitman, W. A.; Fine, A. D.; Raghupathy, N.; Walker, M.; Philip, V. M.; Baker, C. L.; Mahoney, J. M.; Churchill, G. A.; Trowbridge, J. J.; Stitzel, M. L.; Paigen, K.; Petkov, P. M.; Carter, G. W.
10.1101/2022.11.02.514900 — genomics — Posted on 2022-11-02
3796 The neuroprotective effects of estrogen and estrogenic compounds in spinal cord injury
Shvetcov, A.; Ruitenberg, M. J.; Delerue, F.; Gold, W. A.; Brown, D. A.; Finney, C. A.
10.1101/2022.10.30.514438 — neuroscience — Posted on 2022-11-02
3800 Molecular dynamics simulations of the calmodulin-induced alpha-helix in the SK2 calcium-gated potassium ion channel
Ramis, R.; Ballesteros, O. R.; Muguruza-Montero, A.; M-Alicante, S.; Nunez, E.; Villarroel, A.; Leonardo, A.; Bergara, A.
10.1101/2022.11.02.514819 — biophysics — Posted on 2022-11-02
3802 Bax Forms a Membrane Surface Protein-Lipid Complex as it Initiates Apoptosis
Clifton, L. A.; Wacklin-Knecht, H. P.; Aden, J.; Mushtaq, A. U.; Sparrman, T.; Grobner, G.
10.1101/2022.11.01.514672 — biophysics — Posted on 2022-11-02
3803 Structural insights into 3Fe-4S ferredoxins diversity in M.tuberculosis highlighted by a first redox complex with P450.
Gilep, A.; Varaksa, T.; Bukhdruker, S.; Kavaleuski, A.; Ryzhykau, Y.; Smolskaya, S.; Sushko, T.; Tsumoto, K.; Grabovec, I.; Kapranov, I.; Okhrimenko, I.; Marin, E.; Shevtsov, M.; Mishin, A.; Kovalev, K.; Kuklin, A.; Gordeliy, V.; Kaluzhskiy, L.; Gnedenko, O.; Yablokov, E.; Ivanov, A.; Borshchevskiy, V.; Strushkevich, N.
10.1101/2022.11.02.514812 — biochemistry — Posted on 2022-11-02
3804 Ultra-sensitive platelet proteome maps the O-glycosylation landscape and charts the response to thrombin dosage
Houlahan, C.; Kong, Y.; Johnston, B.; Cielesh, M.; Chau, T. H.; Coleman, P.; Hao, H.; Haltiwanger, R. S.; Thaysen-Andersen, M.; Passam, F. H.; Larance, M.
10.1101/2022.11.01.514776 — biochemistry — Posted on 2022-11-02
3810 Co-translational binding of importins to nascent proteins
Seidel, M.; Romanov, N.; Obarska-Kosinska, A.; Becker, A.; Azevedo, N.; Provaznik, J.; Nagaraja, S. R.; Landry, J. J. M.; Benes, V.; Beck, M.
10.1101/2022.11.02.514836 — molecular biology — Posted on 2022-11-02
3811 Enterobacteriaceae isolated from patients share antibiotic resistance conferring plasmids recently acquired from those isolated from sinks in the same treatment room
Taylor, B. P.; Che, Y.; Passarelli, H.; Smollan, G.; Cohen, C.; Rapaport, R.; Tal, I.; Zade, N. P.; Jaber, H.; Keller, N.; Hanage, W. P.; Regev-Yochay, G.
10.1101/2022.11.01.514792 — microbiology — Posted on 2022-11-02
3813 Gut microbiota bacterial strain richness is species specific and limits therapeutic engraftment
Chen-Liaw, A.; Aggarwala, V.; Mogno, I.; Haifer, C.; Eggers, J.; Li, Z.; Helmus, D.; Hart, A.; Wehkamp, J.; Lamouse-Smith, E.; Kerby, R. L.; Rey, F. E.; Colombel, J. F.; Kamm, M.; Borody, T. J.; Grinspan, A.; Paramsothy, S.; Kaakoush, N.; Dubinsky, M. C.; Faith, J. J.
10.1101/2022.11.01.514782 — microbiology — Posted on 2022-11-02
3816 Substantial Neutralization Escape by the SARS-CoV-2 Omicron Variant BQ.1.1
Miller, J.; Hachmann, N.; Collier, A.-r.; Lasrado, N.; Mazurek, C.; Patio, R.; Powers, O.; Surve, N.; Theiler, J.; Korber, B.; Barouch, D. H.
10.1101/2022.11.01.514722 — immunology — Posted on 2022-11-02
3817 Non-invasive temporal interference electrical stimulation of the human hippocampus
Violante, I. R.; Alania, K.; Cassara, A. M.; Neufeld, E.; Acerbo, E.; Carron, R.; Williamson, A.; Kurtin, D. L.; Rhodes, E.; Hampshire, A.; Kuster, N.; Boyden, E. S.; Pascual-Leone, A.; Grossman, N.
10.1101/2022.09.14.507625 — neuroscience — Posted on 2022-11-02
3818 Ketone body metabolism declines with age in mice in a sex-dependent manner
Eap, B.; Nomura, M.; Panda, O.; Garcia, T. Y.; King, C. D.; Rose, J. P.; Leone, T. C.; Kelly, D. P.; Schilling, B.; Newman, J. C.
10.1101/2022.10.05.511032 — physiology — Posted on 2022-11-02
3819 Toeholder: a software for automated design and in silico validation of toehold riboswitches
Cisneros Caballero, A. F.; Rouleau, F. D.; Bautista, C.; Lemieux, P.; Dumont-Leblond, N.
10.1101/2021.11.09.467922 — bioinformatics — Posted on 2022-11-02
3820 Cellular profiling of a recently-evolved social behavior
Johnson, Z. V.; Hegarty, B. E.; Gruenhagen, G. W.; Lancaster, T. J.; McGrath, P. T.; Streelman, J. T.
10.1101/2022.08.09.503380 — animal behavior and cognition — Posted on 2022-11-02
3821 Generalization of contextual fear is sex-specifically affected by high salt intake
Beaver, J. N.; Weber, B. L.; Ford, M. T.; Anello, A. E.; Ruffin, K. M.; Kassis, S. K.; Gilman, L.
10.1101/2022.09.20.508397 — neuroscience — Posted on 2022-11-02
3822 Precision engineering of biological function with large-scale measurements and machine learning
Tack, D. S.; Tonner, P. D.; Pressman, A.; Olson, N. D.; Levy, S. F.; Romantseva, E. F.; Alperovich, N.; Vasilyeva, O.; Ross, D.
10.1101/2022.08.04.502789 — synthetic biology — Posted on 2022-11-02
3823 Curvature Sensing and Membrane Remodeling of the VPS37A N-terminal Domain during Autophagy
Ye, Y.; Liang, X.; Wang, G.; Bewley, M. C.; Liu, X.; Flanagan, J. M.; Wang, H.-G.; Takahashi, Y.; Tian, F.
10.1101/2022.11.01.514784 — biochemistry — Posted on 2022-11-02
3824 Imprinted Dlk1 dosage as a size determinant of the mammalian pituitary gland
Scagliotti, V.; Vignola, M. L.; Willis, T. L.; Howard, M.; Marinelli, E.; Gaston-Massuet, C.; Andoniadou, C. L.; Charalambous, M.
10.1101/2022.11.01.514745 — developmental biology — Posted on 2022-11-02
3825 The midbody and midbody remnant are assembly sites for RNA and active translation
Park, S.; Dahn, R. D.; Kurt, E.; Presle, A.; VandenHeuvel, K.; Moravec, C.; Jambhekar, A.; Olukoga, O. K.; Shepherd, J. D.; Echard, A. D.; Blower, M. D.; Skop, A. R.
10.1101/2022.11.01.514698 — cell biology — Posted on 2022-11-02
3828 AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion
Kneppers, A. E. M.; Theret, M.; Ben Larbi, S.; Gsaier, L.; Saugues, A.; Dabadie, C.; Ferry, A.; Sakamoto, K.; Mounier, R.
10.1101/2022.11.02.514556 — cell biology — Posted on 2022-11-02
3830 OpenFIBSEM: an application programming interface for easy FIB/SEM automation
Cleeve, P.; Dierickx, D.; Buckley, G.; Gorelick, S.; Naegele, L.; Burne, L.; Whisstock, J. C.; de Marco, A.
10.1101/2022.11.01.514681 — cell biology — Posted on 2022-11-02
3831 Primordial germ cells adjust their protrusion type while migrating in different tissue contexts in vivo
Truszkowski, L.; Batur, D.; Long, H.; Tarbashevich, K.; Vos, B. E.; Trappmann, B.; Raz, E.
10.1101/2022.11.02.514858 — cell biology — Posted on 2022-11-02
3832 PARK15/FBXO7 is dispensable for PINK1/Parkin-dependent mitophagy in iNeuron and HeLa cell systems
Kraus, F.; Goodall, E. A.; Smith, I. R.; Jiang, Y.; Paoli, J. C.; Zhang, J.; Paulo, J. A.; Harper, J. W.
10.1101/2022.11.02.514817 — cell biology — Posted on 2022-11-02
3833 Early endosomes act as local exocytosis hubs to repair endothelial membrane damage
Raj, N.; Greune, L.; Kahms, M.; Mildner, K.; Franzkoch, R.; Psathaki, O. E.; Zobel, T.; Zeuschner, D.; Klingauf, J.; Gerke, V.
10.1101/2022.11.02.514845 — cell biology — Posted on 2022-11-02
3838 P bodies coat germ granules to promote transgenerational gene silencing in C. elegans
Du, Z.; Shi, K.; Brown, J. S.; He, T.; Wu, W.-S.; Zhang, Y.; Lee, H.-C.; Zhang, D.
10.1101/2022.11.01.514641 — cell biology — Posted on 2022-11-02
3840 Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal.
Rieskamp, J. D.; Rosado-Burgos, I.; Christofi, J. E.; Ansar, E.; Einstein, D.; Walters, A. E.; Valentini, V.; Bruno, J. P.; Kirby, E. D.
10.1101/2022.10.31.514562 — neuroscience — Posted on 2022-11-02
3842 Genomics highlight an underestimation of the urban heat island effect on red oak phenology
Blumstein, M. J.; Webster, S.; Basler-Chateau, D.; Hopkins, R.; Des Marais, D. L.
10.1101/2022.08.03.502691 — plant biology — Posted on 2022-11-02
3843 Illuminating kinase inhibitors biology by cell signaling profiling.
Medvedev, A.; Makarov, S.; Medvedeva, L. A.; Martsen, E.; Gorman, K. L.; Lin, B.; Makarov, S. S.
10.1101/2022.04.03.486887 — pharmacology and toxicology — Posted on 2022-11-02
3844 Light-driven biological actuators to probe the rheology of 3D microtissues
Mery, A.; Ruppel, A.; Revilloud, J.; Balland, M.; Cappello, G.; Boudou, T.
10.1101/2022.01.05.475039 — biophysics — Posted on 2022-11-02
3849 Lipotype acquisition during neural development in vivo is not recapitulated in stem cell-derived neurons
Gopalan, A. B.; van Uden, L.; Sprenger, R. R.; Fernandez-Novel Marx, N.; Bogetofte, H.; Neveu, P.; Meyer, M.; Noh, K.-M.; Diz-Munoz, A.; Ejsing, C. S.
10.1101/2022.08.31.505694 — developmental biology — Posted on 2022-11-02
3851 Carbon partitioning and metabolic control by the TPT3 triose phosphate translocator of Chlamydomonas reinhardtii
Huang, W.; Krishnan, A.; Plett, A.; Meagher, M.; Linka, N.; Wang, Y.; Ren, B.; Findinier, J.; Redekop, P.; Fakhimi, N.; Kim, R. G.; Karns, D. A.; Boyle, N.; Posewitz, M.; Grossman, A. R.
10.1101/2022.07.25.501471 — microbiology — Posted on 2022-11-02
3853 Accuracy and data efficiency in deep learning models of protein expression
Nikolados, E.-M.; Wongprommoon, A.; Mac Aodha, O.; Cambray, G.; Oyarzun, D. A.
10.1101/2021.11.18.468948 — synthetic biology — Posted on 2022-11-02
3854 LENS - Landscape of Effective Neoantigens Software
Vensko, S. P.; Olsen, K.; Bortone, D. S.; Smith, C. C.; Chai, S.; Beckabir, W.; Fini, M.; Rubinsteyn, A.; Vincent, B.
10.1101/2022.04.01.486738 — cancer biology — Posted on 2022-11-02
3855 The slow evolving genome of the xenacoelomorph worm Xenoturbella bocki
Schiffer, P. H.; Natsidis, P.; Leite, D. J.; Robertson, H.; Lapraz, F.; Marletaz, F.; Fromm, B.; Baudry, L.; Simpson, F.; Hoye, E.; Zakrzewski, A.-C.; Kapli, P.; Hoff, K. J.; Mueller, S.; Marbouty, M.; Marlow, H.; Copley, R. H.; Koszul, R.; Sarkies, P.; Telford, M. J.
10.1101/2022.06.24.497508 — evolutionary biology — Posted on 2022-11-02
3856 Evolution of immune genes in island birds: reduction in population sizes can explain island syndrome
Barthe, M.; Doutrelant, C.; Covas, R.; Melo, M.; Illera, J. C.; Tilak, M.-K.; Colombier, C.; Leroy, T.; Loiseau, C.; Nabholz, B.
10.1101/2021.11.21.469450 — evolutionary biology — Posted on 2022-11-02
3858 COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS.
Tucker, E.; Jimenez, I.; Chen, L.; Bellini, A.; Gorrini, C.; Calton, E.; Gao, Q.; Che, H.; Poon, E.; Jamin, Y.; Martins da Costa, B.; Barker, K.; Shrestha, S.; Hutchinson, C.; Dhariwal, S.; Goodman, A.; Del Nery, E.; Gestraud, P.; Bhalshankar, J.; Iddir, Y.; Saberi-Ansari, E.; Saint-Charles, A.; Geoerger, B.; Marques Da Costa, J.; Pierre-Eugene, C.; Janouiex, I.; Decaudin, D.; Nemati, F.; Carcaboso, A.; Surdez, D.; Delattre, O.; George, S.; Chesler, L.; Tweddle, D.; Schleiermacher, G.
10.1101/2022.10.30.512477 — cancer biology — Posted on 2022-11-02
3860 Allelic and Gene Dosage Effects Involving Uromodulin Aggregates Drive Autosomal Dominant Tubulointerstitial Kidney Disease
Schiano, G.; Lake, J.; Mariniello, M.; Schaeffer, C.; Harvent, M.; Rampoldi, L.; Olinger, E. G.; Devuyst, O.
10.1101/2022.09.13.507770 — genetics — Posted on 2022-11-02
3863 Phosphatidylethanolamine facilitates mitochondrial pyruvate entry to regulate metabolic flexibility
Siripoksup, P.; Cao, G.; Cluntun, A. A. A.; Maschek, J. A.; Pearce, Q.; Lang, M. J.; Eshima, H.; Opurum, P. C.; Mahmassani, Z. S.; Taylor, E. B.; Cox, J. E.; Drummond, M. J.; Rutter, J.; Funai, K.
10.1101/2022.11.01.514767 — physiology — Posted on 2022-11-02
3864 Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods.
Charitakis, N. C.; Salim, A.; Piers, A. T.; Watt, K. I.; Porrello, E. R. C.; Elliott, D. A.; Ramialison, M.
10.1101/2022.10.31.514623 — bioinformatics — Posted on 2022-11-02
3875 The effect of lysergic acid diethylamide (LSD) on whole-brain functional and effective connectivity
Bedford, P.; Hauke, D. J.; Wang, Z.; Roth, V.; Nagy-Huber, M.; Holze, F.; Ley, L.; Vizeli, P.; Liechti, M. E.; Borgwardt, S.; Müller, F.; Diaconescu, A. O.
10.1101/2022.11.01.514687 — neuroscience — Posted on 2022-11-01
3876 Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
Neel, D. V.; Basu, H.; Gunner, G.; Bergstresser, M. D.; Giadone, R. M.; Chung, H.; Miao, R.; Chou, V.; Brody, E. M.; Jiang, X.; Lee, E. B.; Marques, C.; Held, A.; Wainger, B.; Lagier-Tourenne, C.; Zhang, Y.-J.; Petrucelli, L.; Young-Pearse, T.; Chen-Plotkin, A.; Rubin, L. L.; Lieberman, J.; Chiu, I.
10.1101/2022.11.01.513927 — neuroscience — Posted on 2022-11-01
3877 Retinitis pigmentosa associated mutations in mouse Prpf8 cause misexpression of circRNAs and degeneration of cerebellar granule neurons
Krausova, M.; Kreplova, M.; Banik, P.; Kubovciak, J.; Modrak, M.; Zubova, D.; Lindovsky, J.; Kubik-Zahoradna, A.; Palkova, M.; Kolar, M.; Prochazka, J.; Sedlacek, R.; Stanek, D.
10.1101/2022.11.01.514674 — neuroscience — Posted on 2022-11-01
3878 Cholinergic modulation supports DMN suppression during resting state
Sanda, P.; Hlinka, J.; van den Berg, M.; Bazhenov, M.; Keliris, G. A.; Krishnan, G.
10.1101/2022.11.01.514686 — neuroscience — Posted on 2022-11-01
3879 Ketamine induces multiple individually distinct whole-brain functional connectivity signatures
Moujaes, F.; Ji, J. L.; Rahmati, M.; Burt, J.; Schleifer, C. H.; Adkinson, B.; Savic, A.; Santamauro, N.; Tamayo, Z.; Diehl, C.; Kolobaric, A.; Flynn, M.; Rieser, N. M.; Fonteneau, C.; Camarro, T.; Xu, J.; Cho, Y.; Repovs, G.; Fineberg, S.; Morgan, P.; Seifritz, E.; Vollenweider, F. X.; Krystal, J.; Murray, J. D.; Preller, K. H.; Anticevic, A.
10.1101/2022.11.01.514692 — neuroscience — Posted on 2022-11-01
3884 FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
Fujino, Y.; Ueyama, M.; Ishiguro, T.; Ozawa, D.; Sugiki, T.; Ito, H.; Murata, A.; Ishiguro, A.; Gendron, T.; Mori, K.; Tokuda, E.; Taminato, T.; Konno, T.; Koyama, A.; Kawabe, Y.; Takeuchi, T.; Furukawa, Y.; Fujiwara, T.; Ikeda, M.; Mizuno, T.; Mochizuki, H.; Mizusawa, H.; Wada, K.; Ishikawa, K.; Onodera, O.; Nakatani, K.; Taguchi, H.; Petrucelli, L.; Nagai, Y.
10.1101/2022.11.01.514717 — neuroscience — Posted on 2022-11-01
3888 Cellular profiling of a recently-evolved social behavior
Johnson, Z. V.; Hegarty, B. E.; Gruenhagen, G. W.; Lancaster, T. J.; McGrath, P. T.; Streelman, J. T.
10.1101/2022.08.09.503380 — genomics — Posted on 2022-11-01
3890 Sex differences in islet stress responses support female beta cell resilience
Brownrigg, G. P.; Xia, Y. H.; Jamie Chu, C. M.; Wang, S.; Chao, C.; Zhang, J. A.; Skovso, S.; Panzhinskiy, E.; Hu, X.; Johnson, J. D.; Rideout, E. J.
10.1101/2022.05.10.491428 — cell biology — Posted on 2022-11-01
3891 Accelerating the clock: Interconnected speedup of energetic and molecular dynamics during aging in cultured human cells
Sturm, G.; Bobba-Alves, N.; Tumasian, R. A.; Michelson, J.; Ferrucci, L.; Kempes, C. P.; Picard, M.
10.1101/2022.05.10.491392 — cell biology — Posted on 2022-11-01
3892 Organ- and function-specific anatomical organization and bioelectronic modulation of the vagus nerve
Jayaprakash, N.; Toth, V.; Song, W.; Vardhan, A.; Levy, T.; Tomaio, J.; Qanud, K.; Mughrabi, I.; Chang, Y.-C.; Rob, M.; Daytz, A.; Abbas, A.; Nassrallah, Z.; Volpe, B.; Tracey, K. J.; Al-Abed, Y.; Datta-Chaudhuri, T.; Miller, L.; Barbe, M.; Lee, S.; Zanos, T.; Zanos, S.
10.1101/2022.03.07.483266 — neuroscience — Posted on 2022-11-01
3893 Antigen presentation by discrete class I molecules on brain endothelium dynamically regulates T-cell mediated neuropathology in experimental cerebral malaria
Fain, C. E.; Zheng, J.; Jin, F.; Ayasoufi, K.; Wu, Y.; Lilley, M. T.; Dropik, A. R.; Wolf, D. M.; Rodriguez, R. C.; Aibaidula, A.; Tritz, Z. P.; Bouchal, S. M.; Pewe, L. L.; Urban, S. L.; Chen, Y.; Chang, S.-Y.; Hansen, M. J.; Kachergus, J. M.; Shi, J.; Thompson, A. A.; Harty, J. T.; Parney, I. F.; Sun, J.; Wu, L.-J.; Johnson, A. J.
10.1101/2022.10.30.514412 — neuroscience — Posted on 2022-11-01
3903 CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model
Morera, C.; Kim, J.; Paredes-Redondo, A.; Nobles, M.; Rybin, D.; Moccia, R.; Kowala, A.; Meng, J.; Garren, S.; Liu, P.; Morgan, J. E.; Muntoni, F.; Christoforou, N.; Owens, J.; Tinker, A.; Lin, Y.-Y.
10.1101/2022.02.17.480850 — cell biology — Posted on 2022-11-01
3904 The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance
Brazane, M.; Dimitrova, D. G.; Pigeon, J.; Paolantoni, C.; Tao, Y.; Marchand, V.; Da Silva, B.; Schaefer, E.; Angelova, M. T.; Stark, Z.; Delatycki, M.; Dudding, T.; Gecz, J.; Placais, P.-Y.; Teysset, L.; Preat, T.; Piton, A.; Hassan, B. A.; Roignant, J.-Y.; Motorin, Y.; Carre, C.
10.1101/2021.02.06.430044 — molecular biology — Posted on 2022-11-01
3905 Bacterial Microbiome and Host Inflammatory Gene Expression in Foreskin Tissue
Maust, B. S.; Petkov, S.; Herrera, C.; Feng, C.; Brown, B. P.; Lebina, L.; Opoka, D.; Ssemata, A.; Pillay, N.; Serwanga, J.; Seatlholo, P.; Namubiru, P.; Odoch, G.; Mugaba, S.; Seiphetlo, T.; Gray, C. M.; Kaleebu, P.; Webb, E. L.; Martinson, N.; Chiodi, F.; Fox, J.; Jaspan, H. B.; the CHAPS team,
10.1101/2022.08.29.505718 — microbiology — Posted on 2022-11-01
3906 Network Segregation Predicts Processing Speed in the Cognitively Healthy Oldest-old
Nolin, S. A.; Faulkner, M. E.; Stewart, P.; Merritt, S.; Rezaei, R. F.; Bharadwaj, P. K.; Franchetti, M. K.; Raichlen, D. A.; Jessup, C. J.; Hishaw, G. A.; Van Etten, E. J.; Trouard, T. P.; Geldmacher, D.; Wadley, V. G.; Alperin, N.; Porges, E. S.; Woods, A. J.; Cohen, R. A.; Levin, B. E.; Rundek, T.; Alexander, G. E.; Visscher, K. M.
10.1101/2021.10.05.463207 — neuroscience — Posted on 2022-11-01
3908 Essential elements of radical pair magnetosensitivity in Drosophila
Bradlaugh, A.; Fedele, G.; Munro, A.; Hansen, C.; Patel, S.; Kyriacou, C.; Jones, A. R.; Rosato, E.; Baines, R.
10.1101/2021.10.29.466426 — physiology — Posted on 2022-11-01
3909 Skeletal muscle nuclei in mice are not post-mitotic
Borowik, A. K.; Davidyan, A.; Peelor, F. F.; Voloviceva, E.; Doidge, S.; Bubak, M. P.; Mobley, C. B.; McCarthy, J. J.; Dupont-Versteegden, E. E.; Miller, B. F.
10.1101/2022.10.24.513426 — physiology — Posted on 2022-11-01
3911 DiSCERN - Deep Single Cell Expression ReconstructioN for improved cell clustering and cell subtype and state detection
Hausmann, F.; Ergen, C.; Khatri, R.; Marouf, M.; Hänzelmann, S.; Gagliani, N.; Huber, S.; Machart, P.; Bonn, S.
10.1101/2022.03.09.483600 — bioinformatics — Posted on 2022-11-01
3915 Small Molecule Inducers of Neuroprotective miR-132 Identified by HTS-HTS in Human iPSC-derived Neurons
Nguyen, L. D.; Wei, Z.; Silva, M. C.; Barberan-Soler, S.; Rabinovsky, R.; Muratore, C. R.; Stricker, J. M. S.; Hortman, C.; Young-Pearse, T. L.; Haggarty, S. J.; Krichevsky, A. M.
10.1101/2022.11.01.514550 — neuroscience — Posted on 2022-11-01
3919 RNA-mediated double-strand break repair in human cells
Jeon, Y.; Ferrari, M. M.; Channagiri, T.; Xu, P.; Balachander, S.; Park, V. S.; Marsili, S.; Pursell, Z. F.; Jonoska, N.; Storici, F.
10.1101/2022.11.01.514688 — molecular biology — Posted on 2022-11-01
3920 Impaired HIV-specific T-cell responses in HIV and S. mansoni coinfected Ugandans.
Obuku, A. E.; Sharma, A. A.; Rukundo, A.; Odong, M.; Auma, B.; Serwanga, J. S.; Nkangi, R.; Nakitto, Z.; Joloba, M.; Pantaleo, G.; Kaleebu, P.; Sekaly, R. P.
10.1101/2022.11.01.514652 — immunology — Posted on 2022-11-01
3922 Cortical microstructural gradients capture memory network reorganization in temporal lobe epilepsy
Royer, J.; Lariviere, S.; Rodriguez-Cruces, R.; Gift Cabalo, D.; Tavakol, S.; Auer, H.; Park, B.-y.; Paquola, C.; Smallwood, J.; Jefferies, E.; Caciagli, L.; Bernasconi, A.; Bernasconi, N.; Frauscher, B.; Bernhardt, B. C.
10.1101/2022.10.31.513891 — neuroscience — Posted on 2022-11-01
3929 Synchro-PASEF allows precursor-specific fragment ion extraction and interference removal in data-independent acquisition
Skowronek, P.; Krohs, F.; Lubeck, M.; Wallmann, G.; Itang, E.; Koval, P.; Wahle, M.; Thielert, M.; Meier, F.; Willems, S.; Raether, O.; Mann, M.
10.1101/2022.11.01.514654 — biochemistry — Posted on 2022-11-01
3930 Changes in functional composition and gene expression in eukaryotic plankton at the Atlantic-Arctic Polar front
Fremont, P.; Da Silva, C.; Campese, L.; VILLAR, E.; Rastogi, A.; Aury, J.-M.; Bowler, C.; Karp-Boss, L.; Wincker, P.; Pelletier, E.; Gehlen, M.; Iudicone, D.; Jaillon, O.
10.1101/2022.11.01.514737 — genomics — Posted on 2022-11-01
3931 Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men
Sexton, C. L.; Godwin, J. S.; McIntosh, M. C.; Ruple, B. A.; Osburn, S. C.; Hollingsworth, B. R.; Kontos, N. J.; Agostinelli, P. J.; Kavazis, A. N.; Ziegenfuss, T. N.; Lopez, H. L.; Smith, R.; Young, K. C.; Dwaraka, V. B.; Fruge, A. D.; Mobley, C. B.; Sharples, A. P.; Roberts, M. D.
10.1101/2022.11.01.514721 — molecular biology — Posted on 2022-11-01
3933 Inactivation of Influenza A virus by pH conditions encountered in expiratory aerosol particles results from localized conformational changes within Haemagglutinin and Matrix 1 proteins.
David, S. C.; Vadas, O.; Glas, I.; Schaub, A.; Luo, B.; D'Angelo, G. C.; Paz Montoya, J.; Bluvshtein, N.; Hugentobler, W.; Klein, L.; Motos, G.; Pohl, M.; Violaki, K.; Nenes, A.; Krieger, U.; Stertz, S.; Peter, T.; Kohn, T.
10.1101/2022.11.01.514690 — microbiology — Posted on 2022-11-01
3934 Within-patient and global evolutionary dynamics of Klebsiella pneumoniae ST17
Hetland, M. A. K.; Hawkey, J.; Bernhoff, E.; Bakksjo, R.-J.; Kaspersen, H.; Rettedal, S. I.; Sundsfjord, A.; Holt, K. E.; Löhr, I. H.
10.1101/2022.11.01.514664 — microbiology — Posted on 2022-11-01
3936 Nanosized extracellular vesicles released by Neurospora crassa hyphae
Medina-Castellanos, E.; Salgado-Bautista, D. A.; Martinez-Andrade, J. M.; Cadena-Nava, R. D.; Riquelme, M.
10.1101/2022.11.01.514727 — microbiology — Posted on 2022-11-01
3938 Dual function of the O-antigen WaaL ligase of Aggregatibacter actinomycetemcomitans
Danforth, D.; Melloni, M.; Thorpe, R.; Cohen, A. J.; Voogt, R.; Tristano, J.; Mintz, K.
10.1101/2022.10.31.514599 — microbiology — Posted on 2022-11-01
3939 A CRISPRi-based genetic resource to study essential Staphylococcus aureus genes
Reed, P.; Sorg, M.; Alwardt, D.; Serra, L.; Veiga, H.; Schaeper, S.; Pinho, M. G.
10.1101/2022.10.31.514627 — microbiology — Posted on 2022-11-01
3941 Automated analysis of PD1 and PDL1 in lymph nodes and the microenvironment of transmissible tumors in Tasmanian devils
Russell, G. G.; Palmieri, C.; Darby, J.; Morris, G. P.; Fountain-Jones, N. M.; Pye, R.; Flies, A. S.
10.1101/2022.10.31.513798 — immunology — Posted on 2022-11-01
3942 Predestined neutrophil heterogeneity in homeostasis varies in transcriptional and phenotypic response to Candida
Scherer, A. K.; Hopke, A.; Xu, S.; Viens, A.; Alexander, N. J.; Timmer, K. D.; Archambault, D.; Floyd, D.; Atallah, N. J.; Rhee, C.; Cetinbas, M.; Scadden, D.; Irimia, D.; Sykes, D. B.; Sadreyev, R. I.; Mansour, M. K.
10.1101/2022.11.01.514676 — immunology — Posted on 2022-11-01
3943 DNA-PKcs is required for cGAS/STING-dependent viral DNA sensing in human cells
Hristova, D. B.; Oliveira, M.; Wagner, E.; Melcher, A.; Harrington, K. J.; Belot, A.; Ferguson, B. J.
10.1101/2022.11.01.514678 — immunology — Posted on 2022-11-01
3945 A low-cost recombinant glycoconjugate vaccine confers immunogenicity and protection against enterotoxigenic Escherichia coli infections in mice
Williams, A. J.; Warfel, K. F.; Desai, P.; Li, J.; Lee, J.-J.; Wong, D. A.; Sobol, S. E.; Jewett, M. C.; Chang, Y.-F.; DeLisa, M. P.
10.1101/2022.10.31.514630 — synthetic biology — Posted on 2022-11-01
3946 Cooltools: enabling high-resolution Hi-C analysis in Python
Open 2C, ; Abdennur, N.; Abraham, S.; Fudenberg, G.; Flyamer, I. M.; Galitsyna, A. A.; Goloborodko, A.; Imakaev, M.; Oksuz, B. A.; Venev, S. V.
10.1101/2022.10.31.514564 — bioinformatics — Posted on 2022-11-01
3948 Structure of the human UBR5 E3 ubiquitin ligase
Wang, F.; He, Q.; Zhan, W.; Yu, Z.; Fink-Groner, E.; Ma, X.; Lin, G.; Li, H.
10.1101/2022.10.31.514604 — biochemistry — Posted on 2022-11-01
3953 Genomics and Phenomics Enabled Prebreeding Improved Early-Season Chilling Tolerance in Sorghum
Marla, S. R.; Felderhoff, T.; Hayes, C.; Perumal, R.; Wang, X.; Poland, J.; Morris, G. P.
10.1101/2022.10.31.514536 — genetics — Posted on 2022-11-01
3954 HAND1 knockdown disrupts trophoblast global gene expression
Fresch, R.; Courtney, J. A.; Brockway, H. M.; Wilson, R.; Jones, H.
10.1101/2022.11.01.514704 — genetics — Posted on 2022-11-01
3957 Profiling cell envelope-antibiotic interactions reveals vulnerabilities to β-lactams in a multidrug-resistant bacterium
Hogan, A. M.; Maydaniuk, D. T.; Natarajan, A.; Leon, B.; Batun, Z.; Motnenko, A.; Bosch, A.; Cardona, S. T.
10.1101/2022.11.01.510852 — microbiology — Posted on 2022-11-01
3963 Targeting AAV vectors to the CNS via de novo engineered capsid-receptor interactions
Huang, Q.; Chen, A. T.; Chan, K. Y.; Sorensen, H.; Barry, A. J.; Azari, B.; Beddow, T.; Zheng, Q.; Zhao, B.; Tobey, I. G.; Eid, F.-E.; Chan, Y. A.; Deverman, B. E.
10.1101/2022.10.31.514553 — synthetic biology — Posted on 2022-11-01
3964 Genome editing in plants using the compact editor Cas{Phi}
Li, Z.; Zhong, Z.; Wu, Z.; Pausch, P.; Al-Shayeb, B.; Amerasekerae, J.; Doudna, J. A.; Jacobsen, S. E.
10.1101/2022.10.31.514567 — plant biology — Posted on 2022-11-01
3965 A secreted protease-like protein in Zymoseptoria tritici is responsible for avirulence on Stb9 resistance gene in wheat
AMEZROU, R.; AUDEON, C.; COMPAIN, J.; GELISSE, S.; DUCASSE, A.; SAINTENAC, C.; LAPALU, N.; ORFORD, S.; CROLL, D.; AMSELEM, J.; FILLINGER, S.; MARCEL, T. C.
10.1101/2022.10.31.514577 — plant biology — Posted on 2022-11-01
3966 Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart
Zhang, M.; Feng, N.; Thapa, D.; Stoner, M. W.; Manning, J. R.; McTiernan, C. F.; Yang, X.; Peng, Z.; Jurczak, M. J.; Guimaraes, D.; Shiva, S.; Kaufman, B. A.; Sack, M. N.; Scott, I.
10.1101/2022.10.31.514513 — physiology — Posted on 2022-11-01
3969 The aminoglycoside streptomycin triggers ferroptosis in tumor initiating cells
Guillorit, H.; Relier, S.; Zagiel, B.; Di Giorgio, A.; Cazevieille, C.; Bansard, L.; Bouclier, C.; Mialhe, X.; Brisset, M.; Hideg, S.; Choquet, A.; Planque, C.; Bastide, A.; Pannequin, J.; Duca, M.; Macari, F.; David, A.
10.1101/2022.10.31.514281 — cancer biology — Posted on 2022-11-01
3971 Learning the shape of protein micro-environments with a holographic convolutional neural network
Pun, M. N.; Ivanov, A.; Bellamy, Q.; Montague, Z.; LaMont, C.; Bradley, P.; Otwinowski, J.; Nourmohammad, A.
10.1101/2022.10.31.514614 — biophysics — Posted on 2022-11-01
3979 Optimization of genomewide CRISPR screens using AsCas12a and multi-guide arrays
Petiwala, S.; Modi, A.; Anton, T.; Murphy, E.; Kadri, S.; Hu, H.; Lu, C.; Flister, M. J.; Verduzco, D.
10.1101/2022.10.31.514561 — genetics — Posted on 2022-11-01
3981 Historical use of coastal wetlands by small-scale fisheries in the Northern Gulf of California
Morzaria-Luna, H. N.; Urquidi, M.; Cruz-Pinon, G.; Dorantes Hernandez, J. M.; Valdivia Jimenez, P. A.; Sanchez Cruz, A.; Martinez, I.
10.1101/2022.10.31.513536 — ecology — Posted on 2022-11-01
3982 Reemergence of cholera in Haiti
Rubin, D. H.; Zingl, F. G.; Leitner, D. R.; Ternier, R.; Compere, V.; Marseille, S.; Slater, D. M.; Harris, J. B.; Chowdhury, F.; Qadri, F.; Boncy, J.; Ivers, L. C.; Waldor, M. K.
10.1101/2022.10.31.514591 — microbiology — Posted on 2022-11-01
3984 A novel anti-cancer therapy with nuclear export inhibitor Selinexor in combination with oncolytic myxoma virus
Rahman, M. M.; Oosterom, F. v.; Enow, J. A.; Hossain, M.; Gutierrez-Jensen, A. D.; Cashen, M.; Everts, A.; Lowe, K.; Kilbourne, J.; Daggett-Vondras, J.; Karr, T. L.; McFadden, G.
10.1101/2022.10.31.514585 — microbiology — Posted on 2022-11-01
3986 Calcium and Bicarbonate Signaling Pathways have Pivotal, Resonating Roles in Matching ATP Production to Demand
Greiser, M.; Karbowski, M.; Kaplan, A. D.; Coleman, A. K.; Mannella, C. A.; Lederer, W. J.; Boyman, L.
10.1101/2022.10.31.514581 — physiology — Posted on 2022-11-01
3987 In-vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma
DeBerardinis, R. J.; Kaushik, A.; Burroughs, L. K.; Tarangelo, A.; Ragavan, M.; Wu, C.-Y.; Li, X.; Ahumada, K.; Tcheuyap, V. T.; Saatchi, F.; Do, Q.; Yong, C.; Rosales, T.; Stevens, C.; Rao, A. D.; Faubert, B.; Pachnis, P.; Zacharias, L. G.; Vu, H.; Cai, F.; Mathews, T. P.; Slusher, B. S. P.; Kapur, P.; Sun, X.; Merritt, M.; Brugarolas, J.; Zhang, Y.; Chiang, J.-C.; Genovese, G.
10.1101/2022.10.31.514397 — cancer biology — Posted on 2022-11-01
3988 Glutamine mimicry suppresses tumor progression through asparagine metabolism in pancreatic ductal adenocarcinoma
Recouvreux, M. V.; Galapate, C. M.; Grenier, S.; Esparza, E.; Zhang, Y.; Maganti, S.; Naeem, R.; Scott, D. A.; Lowy, A. M.; Tiriac, H.; Commisso, C.
10.1101/2022.10.31.514261 — cancer biology — Posted on 2022-11-01
3989 Nascent-Chain Interaction Networks and Their Effect on the Bacterial Ribosome
Masse, M. M.; Guzman-Luna, V.; Varela, A. E.; Hutchinson, R. B.; Srivastava, A.; Wei, W.; Fuchs, A. M.; Cavagnero, S.
10.1101/2022.10.31.514555 — biophysics — Posted on 2022-11-01
3991 An optimised method for recovery and quantification of laboratory generated SARS-CoV-2 aerosols by plaque assay.
Byrne, R. L.; Gould, S.; Edwards, T.; Wooding, D.; Atkinson, B.; Moore, G.; Collings, K.; Boisdon, C.; Maher, S.; Biagini, G.; Adams, E. R.; Fletcher, T.; Pennington, S. H.
10.1101/2022.10.31.514483 — molecular biology — Posted on 2022-11-01
3992 mRNA bivalent booster enhances neutralization against BA.2.75.2 and BQ.1.1
Davis-Gardner, M. E.; Lai, L.; Wali, B.; Samaha, H.; Solis, D.; Lee, M.; Porter-Morrison, A.; Hentenaar, I. T.; Yamamoto, F.; Godbole, S.; Douek, D. C.; Lee, F. E.-H.; Rouphael, N.; Moreno, A.; Pinsky, B. A.; Suthar, M. S.
10.1101/2022.10.31.514636 — immunology — Posted on 2022-11-01
3993 Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody to antigenically distinct omicron SARS-CoV-2 subvariants
Changrob, S.; Halfmann, P. J.; Liu, H.; Torres, J. L.; McGrath, J. J. C.; Ozorowski, G.; Li, L.; Kuroda, M.; Maemura, T.; Huang, M.; Wilbanks, D. G.; Zheng, N.-Y.; Turner, H. L.; Erickson, S. A.; Fu, Y.; Singh, G.; Krammer, F.; Sather, D. N.; Ward, A. B.; Wilson, I. A.; Kawaoka, Y.; Wilson, P. C.
10.1101/2022.10.31.514592 — immunology — Posted on 2022-11-01
3998 Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line
Moradi Marjaneh, M.; Kirk, E. P.; Patrick, R.; Alankerage, D.; Humphreys, D. T.; Del Monte-Nieto, G.; Janbandhu, V.; Doan, T.; Dunwoodie, S. L.; Wong, E. S.; Moran, C.; Martin, I. C. A.; Thomson, P. C.; Harvey, R. P.
10.1101/2022.10.31.514499 — genetics — Posted on 2022-11-01
4001 Landscape heterogeneity and soil biota are central to multi-taxa diversity for landscape restoration
Montoya Sanchez, V.; Kreft, H.; Arimond, I.; Ballauff, J.; Berkelmann, D.; Brambach, F.; Daniel, R.; Grass, I.; Hines, J.; Hoelscher, D.; Irawan, B.; Krause, A.; Polle, A.; Potapov, A.; Sachsenmaier, L.; Scheu, S.; Sundawati, L.; Tscharntke, T.; Zemp, D. C.; Guerrero Ramirez, N. R.
10.1101/2022.10.31.514517 — ecology — Posted on 2022-11-01
4005 Prospective isolation according to melanin pigment content of melanoma cells with heterogeneous potentials for disease propagation
Fedele, C.; Kuser Abali, G.; Rossi, R.; Zhao, P.; Li, J.; Szeto, P.; Zhang, Y.; Wong, N. C.; Andrews, M.; Shackleton, M.
10.1101/2022.10.31.514484 — cancer biology — Posted on 2022-11-01
4012 Falign: An effective alignment tool for long noisy 3C data
Xiao, C.-L.; Chen, Y.; Lin, Z.-B.; Niu, L.-J.; Zhong, J.-Y.; Liu, Y.-Z.; Hou, C.-H.; Luo, F.
10.1101/2022.10.30.514399 — bioinformatics — Posted on 2022-11-01
4013 Dually biofortified cisgenic tomatoes with increased flavonoids and branched-chain amino acids content
Vazquez-Vilar, M.; Fernandez-del-Carmen, A.; Garcia-Carpintero, V.; Drapal, M.; Presa, S.; Ricci, D.; Diretto, G.; Rambla, J. L.; Fernandez-Munoz, R.; Espinosa-Ruiz, A.; Fraser, P. D.; Martin, C.; Granell, A.; Orzaez, D.
10.1101/2022.10.31.514528 — bioengineering — Posted on 2022-11-01
4014 e-cone and d-cone singularities drive submucosal collagen fiber remodeling in intestinal anastomotic surgery
Fleischer, B.; Nguyen, N.; Pal, A.; Khabaz, K.; Tsamis, A.; Efrati, E.; Witten, T.; Alverdy, J.; Pocivavsek, L.
10.1101/2022.10.31.514540 — bioengineering — Posted on 2022-11-01
4015 Sphere-sequencing unveils local tissue microenvironments at single cell resolution
Handler, K.; Bach, K.; Borrelli, C.; Ficht, X.; Acar, I. E.; Moor, A. E.
10.1101/2022.10.31.514509 — genomics — Posted on 2022-11-01
4020 Different helminth parasites show contrasting relationships with age in a wild ungulate
Albery, G. F.; Morris, S.; Morris, A.; Kenyon, F.; McBean, D.; Pemberton, J. M.; Nussey, D. H.; Firth, J. A.
10.1101/2022.10.31.514008 — ecology — Posted on 2022-11-01
4023 RSV-induced Expanded Ciliated Cells Contribute to Bronchial Wall Thickening
Talukdar, S. N.; Osan, J.; Ryan, K.; Grove, B.; Perley, D.; Kumar, B. D.; Yang, S.; Dallman, S.; Hollingsworth, L.; Bailey, K. L.; Mehedi, M.
10.1101/2022.10.31.514471 — microbiology — Posted on 2022-11-01
4025 Paradox Found: Global Accounting of Lymphocyte Protein Synthesis
Seedhom, M.; Dersh, D.; Holly, J.; Pavon-Eternod, M.; Wei, J.; Shores, L.; David, A.; Santos, J.; Hickman, H.; Yewdell, J.
10.1101/2022.10.31.514539 — immunology — Posted on 2022-11-01
4031 Breast cancer progression and metastasis to lymph nodes reveals cancer cell plasticity and MHC class II-mediated immune regulation
Lei, P.-J.; Pereira, E.; Andersson, P.; Amoozgar, Z.; Wijnbergen, J. W. V.; O'Melia, M. J.; Zhou, H.; Chatterjee, S.; Ho, W. W.; Posada, J. M.; Kumar, A. S.; Morita, S.; Chuang, C.; Ergin, I.; Jones, D.; Huang, P.; Beyaz, S.; Padera, T. P.
10.1101/2022.10.30.514441 — cancer biology — Posted on 2022-11-01
4044 Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing Mcl-1-addicted cancer cells
Sneyers, F.; Kerkhofs, M.; Welkenhuyzen, K.; Speelman-Rooms, F.; Shemy, A.; Voet, A. R.; Eelen, G.; Dewerchin, M.; Tait, S.; Ghesquiere, B.; Bootman, M. D.; Bultynck, G.
10.1101/2022.10.31.512457 — cell biology — Posted on 2022-11-01
4045 Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I.
Okuma, H.; Saijo-Hamano, Y.; Sherif, A. A.; Hoshizaki, E.; Sakai, N.; Kato, T.; Imasaki, T.; Nitta, E.; Sasai, M.; Maniwa, Y.; Kosako, H.; Standley, D. M.; Yamamoto, M.; Nitta, R.
10.1101/2022.10.31.514472 — microbiology — Posted on 2022-11-01
4046 CRISPR/FnCas12a-mediated efficient multiplex and iterative genome editing in bacterial plant pathogens without donor DNA templates
Yan, F.; Wang, J.; Zhang, S.; Lu, Z.; Li, S.; Ji, Z.; Song, C.; Chen, G.; Xu, J.; Feng, J.; Zhou, X.; Zhou, H.
10.1101/2022.10.31.514474 — microbiology — Posted on 2022-11-01
4048 Druggable Growth Dependencies and Tumor Evolution Analysis in Patient-Derived Organoids of Neuroendocrine Cancer
Dayton, T. L.; Alcala, N.; Moonen, L.; den Hartigh, L.; Mangiante, L.; Lap, L.; Dost, A. F. M.; Beumer, J.; Levy, S.; van Leeuwaarde, R. S.; Hackeng, W. M.; Samsom, K.; Voegele, C.; Sexton-Oates, A.; Begthel, H.; Korving, J.; Hillen, L.; Brosens, L. A. A.; Lantuejoul, S.; Jaksani, S.; Kok, N. F. M.; Hartemink, K. J.; Klomp, H. M.; Rinkes, I. H. M. B.; Dingemans, A.-M.; Valk, G. D.; Vriens, M. R.; Buikhuisen, W.; van den Berg, J.; Tesselaar, M.; Derks, J.; Speel, E. J.; Foll, M.; Fernandez-Cuesta, L.; Clevers, H.
10.1101/2022.10.31.514549 — cancer biology — Posted on 2022-11-01
4049 Neotelomere formation by human telomerase
Kinzig, C. G.; Zakusilo, G.; Takai, K. K.; de Lange, T.
10.1101/2022.10.31.514589 — cancer biology — Posted on 2022-11-01
4051 USP10 strikes down Wnt/β-catenin signaling by dual-wielding deubiquitinase activity and phase transition potential
Wang, Y.; Mao, A.; Liu, J.; Li, P.; Zheng, S.; Tong, T.; Li, Z.; Zhang, H.; Ma, L.; Lin, J.; Pang, Z.; Han, Q.; Li, F.; Zhang, X.; Chen, M.; He, X.; Zhang, X.; Fei, T.; Liu, B.; Gao, D.; Cao, L.; Wang, Q.; Li, Y.; Sheng, R.
10.1101/2022.10.31.514466 — cell biology — Posted on 2022-11-01
4052 Chronological aging impacts abundance, function and microRNA content of extracellular vesicles produced by human epidermal keratinocytes
Nedachi, T.; Bonod, C.; Rorteau, J.; Chinoune, W.; Ischiuchi, Y.; Hugues, S.; Gillet, B.; Sigaudo-Roussel, D.; Lamartine, J.
10.1101/2022.10.31.514487 — cell biology — Posted on 2022-11-01
4053 The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
Lavie, J.; Lalou, C.; Mahouf, W.; Dupuy, J.-W.; Lacaule, A.; Ars, A.; Lacombe, D.; Duchene, A.-M.; Raymond, A.-A.; Rezvani, H. R.; Ngondo, P.; Benard, G.
10.1101/2022.11.01.514535 — cell biology — Posted on 2022-11-01
4054 Allosteric inhibition of the epidermal growth factor receptor through disruption of transmembrane interactions
Rybak, J. A.; Sahoo, A. R.; Kim, S.; Pyron, R. J.; Pitts, S. B.; Guleryuz, S.; Smith, A. W.; Buck, M.; Barrera, F. N.
10.1101/2022.10.31.514582 — cell biology — Posted on 2022-11-01
4055 Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development
Aljiboury, A. A.; Ingram, E.; Krishnan, N.; Ononiwu, F.; Pal, D.; Manikas, J.; Taveras, C.; Hall, N. A.; Da Silva, J.; Freshour, J.; Hehnly, H.
10.1101/2022.10.31.514532 — cell biology — Posted on 2022-11-01
4057 An Iron-Calcium-Miro Axis Influences Parkinson Risk and Neurodegeneration
Bharat, V.; Vanhauwaert, R.; Li, L.; Muir, C. M.; Durairaj, A. S.; Chandra, S.; Le Guen, Y.; Nandakishore, P.; Hsieh, C.-H.; Rensi, S. E.; Altman, R.; Greicius, M. D.; Feng, L.; Wang, X.
10.1101/2022.10.30.513580 — cell biology — Posted on 2022-11-01
4061 Self-Assembly of Tunable Intrinsically DisorderedPeptide Amphiphiles
Ehm, T.; Shinar, H.; Jacoby, G.; Meir, S.; Koren, G.; Segal Asher, M.; Korpanty, J.; Thompson, M. P.; Gianneschi, N. C.; Kozlov, M. M.; Azoulay-Ginsbur, S. E.; Amir, R.; Raedler, J. O.; Beck, R.
10.1101/2022.10.28.514176 — biophysics — Posted on 2022-11-01
4062 Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells
Sakata, Y.; Cheng, K.; Mayama, M.; Seita, Y.; Detlefsen, A. J.; Mesaros, C. A.; Penning, T. M.; Shishikura, K.; Yang, W.; Auchus, R. J.; Strauss, J. F.; Sasaki, K.
10.1101/2022.10.31.514433 — developmental biology — Posted on 2022-11-01
4064 System-wide mapping of neuropeptide-GPCR interactions in C. elegans
Beets, I.; Zels, S.; Vandewyer, E.; Demeulemeester, J.; Caers, J.; Baytemur, E.; Schafer, W. R.; Vertes, P. E.; Mirabeau, O.; Schoofs, L.
10.1101/2022.10.30.514428 — neuroscience — Posted on 2022-11-01
4065 Axon guidance pathways modulate neurotoxicity of ALS-associated UBQLN2
Kim, S. H.; Nichols, K. D.; Anderson, E. N.; Liu, Y.; Ramesh, N.; Jia, W.; Kuerbis, C. J.; Scalf, M.; Smith, L. M.; Pandey, U. B.; Tibbetts, R. S.
10.1101/2022.10.31.514355 — neuroscience — Posted on 2022-11-01
4066 Psychedelics enhance the effects of brain stimulation in rodents
Dwiel, L.; Henricks, A. M.; Bragg, E.; Nicol, J.; Gui, J.; Doucette, W.
10.1101/2022.10.31.514588 — neuroscience — Posted on 2022-11-01
4067 YTHDF2 in dentate gyrus is the m6A reader mediating m6A modification in hippocampus-dependent learning and memory
Zhuang, M.; Geng, X.; Han, P.; Liang, F.; Che, P.; Liu, C.; Yang, L.; Yu, J.; Zhang, Z.; Dong, W.; Ji, S.-J.
10.1101/2022.10.31.514574 — neuroscience — Posted on 2022-11-01
4068 Antigen presentation by discrete class I molecules on brain endothelium dynamically regulates T-cell mediated neuropathology in experimental cerebral malaria
Fain, C. E.; Zheng, J.; Jin, F.; Ayasoufi, K.; Wu, Y.; Lilley, M. T.; Dropik, A. R.; Wolf, D. M.; Rodriguez, R. C.; Aibaidula, A.; Tritz, Z. P.; Bouchal, S. M.; Pewe, L. L.; Urban, S. L.; Chen, Y.; Chang, S.-Y.; Hansen, M. J.; Kachergus, J. M.; Shi, J.; Thompson, A. A.; Harty, J. T.; Parney, I. F.; Sun, J.; Wu, L.-J.; Johnson, A. J.
10.1101/2022.10.30.514412 — neuroscience — Posted on 2022-11-01
4071 Intermediate Gray Matter Interneurons in the Lumbar Spinal Cord Play a Critical and Necessary Role in Coordinated Locomotion
Kuehn, N.; Schwarz, A.; Beretta, C. A.; Schwarte, Y.; Schmitt, F.; Motsch, M.; Weidner, N.; Puttagunta, R.
10.1101/2022.10.31.514612 — neuroscience — Posted on 2022-11-01
4073 A mesocorticolimbic signature of pleasure in the human brain
Kragel, P. A.; Treadway, M. T.; Admon, R.; Pizzagalli, D. A.; Hahn, E. C.
10.1101/2022.10.31.514244 — neuroscience — Posted on 2022-11-01
4074 TRPA1 activation in non-sensory supporting cells contributes to regulation of cochlear sensitivity after acoustic trauma
Velez-Ortega, A. C.; Stepanyan, R.; Edelmann, S. E.; Torres-Gallego, S.; Park, C.; Marinkova, D. A.; Nowacki, J. S.; Sinha, G. P.; Frolenkov, G. I.
10.1101/2022.10.30.514409 — neuroscience — Posted on 2022-11-01
4075 A multivariate regressor of patterned dopamine release predicts relapse to cocaine
Lujan, M. A.; Young-Morrison, R.; Engi, S. A.; Oliver, B. L.; Zhang, L.-Y.; Wenzel, J. M.; Li, Y.; Zlebnik, N. E.; Cheer, J. F.
10.1101/2022.10.31.514534 — neuroscience — Posted on 2022-11-01
4081 Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule regulation
Pinzi, L.; Conze, C.; Bisi, N.; Torre, G. D.; Monteiro-Abreu, N.; Trushina, N. I.; Soliman, A.; Krusenbaum, A.; Dolouei, M. K.; Hellwig, A.; Christodoulou, M. S.; Passarella, D.; Bakota, L.; Rastelli, G.; Brandt, R.
10.1101/2022.10.31.514565 — neuroscience — Posted on 2022-11-01
4082 Neurofluid Coupling during Sleep and Wake States
Vijayakrishnan Nair, V.; R Kish, B.; Li Hui Chong, P.; Yang, H.-C.; Wu, Y.-C.; Tong, Y.; Schwichtenberg, A.
10.1101/2022.10.31.514639 — neuroscience — Posted on 2022-11-01
4083 Excessive Firing of Dyskinesia-Associated Striatal Direct Pathway Neurons is Gated By Dopamine and Excitatory Synaptic Input
Ryan, M. B.; Girasole, A. E.; McGregor, M. M.; Brakaj, R.; Paletzki, R. F.; Gerfen, C. R.; Nelson, A. B.
10.1101/2022.10.31.514594 — neuroscience — Posted on 2022-11-01
4085 Ultrastructural effects of sleep and wake on the parallel fiber synapses of the cerebellum
Loschky, S. S.; Spano, G. M.; Marshall, W.; Schroeder, A.; Nemec, K. M.; Schiereck, S. S.; de Vivo, L.; Bellesi, M.; Banningh, S. W.; Tononi, G.; Cirelli, C.
10.1101/2022.10.31.514498 — neuroscience — Posted on 2022-11-01
4086 Cholesterol-containing liposomes decorated with Au nanoparticles as minimal tunable fusion machinery
Canepa, E.; Bochicchio, D.; Silva, P. H. J.; Stellacci, F.; Dante, S.; Rossi, G.; Relini, A.
10.1101/2022.10.28.514049 — biophysics — Posted on 2022-11-01
4087 Effect of Nrf2 Loss on Senescence and Cognition of Tau-Based P301S Mice
Riordan, R. T.; Wang, R.; Yu, Z.; Ross, G.; Valerio, J.; Dimas-Munoz, J.; Heredia, V.; Magnusson, K. R.; Galvan, V.; Perez, V. I.
10.1101/2022.10.31.514571 — animal behavior and cognition — Posted on 2022-11-01
4092 LRRK2 regulates dendritic spine dynamics through interaction with post-synaptic actin cytoskeleton
Tombesi, G.; Chen, C.; Favetta, G.; Plotegher, N.; Sevegnani, M.; Marte, A.; Battisti, I.; Civiero, L.; Onofri, F.; Piccoli, G.; Arrigoni, G.; Manzoni, C.; Parisiadou, L.; Greggio, E.
10.1101/2022.10.31.514622 — neuroscience — Posted on 2022-11-01
4094 Aging impairs astrocytes in the human cerebral cortex
Popov, A.; Brazhe, N.; Morozova, K.; Yashin, K.; Bychkov, M.; Nosova, O.; Sutyagina, O.; Brazhe, A.; Parshina, E.; Li, L.; Medyanik, I.; Korzhevskii, D. E.; Shenkarev, Z.; Lyukmanova, E.; Verkhratsky, A.; Semyanov, A.
10.1101/2022.10.31.514523 — neuroscience — Posted on 2022-11-01
4096 High-Resolution EEG Source Reconstruction with Boundary Element Fast Multipole Method Using Reciprocity Principle and TES Forward Model Matrix
Wartman, W. A.; Raij, T.; Rachh, M.; Lin, F.-H.; Weise, K.; Knoesche, T. R.; Maess, B.; Wolters, C. H.; Haemaelaeinen, M.; Nummenmaa, A. R.; Makaroff, S. N.
10.1101/2022.10.30.514418 — neuroscience — Posted on 2022-11-01
4099 LRRK2 regulates dendritic spine dynamics through interaction with post-synaptic actin cytoskeleton
Tombesi, G.; Chen, C.; Favetta, G.; Plotegher, N.; Sevegnani, M.; Marte, A.; Battisti, I.; Civiero, L.; Onofri, F.; Piccoli, G.; Arrigoni, G.; Manzoni, C.; Parisiadou, L.; Greggio, E.
10.1101/2022.10.31.514622 — neuroscience — Posted on 2022-11-01
4100 FGF21 has a sex-specific role in calorie-restriction-induced beiging of white adipose tissue in mice
Calubag, M. F.; Ademi, I.; Yeh, C.-Y.; Babygirija, R.; Bhoopat, A. M.; Kasza, I.; Sonsalla, M. M.; Green, C. L.; Pak, H. H.; Lamming, D.
10.1101/2022.07.29.501882 — physiology — Posted on 2022-11-01