date is 2018-01
Select an archive month  
May 2025
April 2025
March 2025
February 2025
January 2025
December 2024
November 2024
October 2024
September 2024
August 2024
July 2024
June 2024
May 2024
April 2024
March 2024
February 2024
January 2024
December 2023
November 2023
October 2023
September 2023
August 2023
July 2023
June 2023
May 2023
April 2023
March 2023
February 2023
January 2023
December 2022
November 2022
October 2022
September 2022
August 2022
July 2022
June 2022
May 2022
April 2022
March 2022
February 2022
January 2022
December 2021
November 2021
October 2021
September 2021
August 2021
July 2021
June 2021
May 2021
April 2021
March 2021
February 2021
January 2021
December 2020
November 2020
October 2020
September 2020
August 2020
July 2020
June 2020
May 2020
April 2020
March 2020
February 2020
January 2020
December 2019
November 2019
October 2019
September 2019
August 2019
July 2019
June 2019
May 2019
April 2019
March 2019
February 2019
January 2019
December 2018
November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013

Archive, 2018-01

4 Ferrous iron mediates translation
Bray, M. S.; Bowman, J. C.; Petrov, A. S.; Williams, L. D.; Glass, J. B.
10.1101/256958 — biochemistry — Posted on 2018-01-31
6 Biased competition in the absence of input bias: predictions from corticostriatal computation
Ardid, S.; Sherfey, J. S.; McCarthy, M. M.; Hass, J.; Pittman-Polletta, B. R.; Kopell, N.
10.1101/258053 — neuroscience — Posted on 2018-01-31
11 Mitochondrial targeting of glycolysis in a major lineage of eukaryotes
Rio Bartulos, C.; Rogers, M. B.; Williams, T. A.; Gentekaki, E.; Brinkmann, H.; Cerff, R.; Liaud, M.-F.; Hehl, A. B.; Yarlett, N. R.; Gruber, A.; Kroth, P. G.; van der Giezen, M.
10.1101/257790 — evolutionary biology — Posted on 2018-01-31
12 Gene flow mediates the role of sex chromosome meiotic drive during complex speciation
Meiklejohn, C. D.; Landeen, E. L.; Gordon, K. E.; Rzatkiewicz, T.; Kingan, S. B.; Geneva, A. J.; Vedanayagam, J. P.; Muirhead, C. A.; Garrigan, D.; Stern, D. L.; Presgraves, D. C.
10.1101/024711 — evolutionary biology — Posted on 2018-01-31
16 Microfluidics for Electrophysiology, Imaging, and Behavioral Analysis of Hydra
Badhiwala, K.; Gonzales, D. L.; Vercosa, D. G.; Avants, B.; Robinson, J.
10.1101/257691 — neuroscience — Posted on 2018-01-31
19 Comprehensive antibiotic-linked mutation assessment by Resistance Mutation Sequencing (RM-seq)
Guerillot, R.; Li, L.; Baines, S.; Howden, B. O.; Schultz, M.; Seemann, T.; Monk, I.; Pidot, S. J.; Gao, W.; Giulieri, S.; Goncalves da Silva, A.; D'Agata, A.; Tomita, T.; Peleg, A. Y.; Stinear, T. P.; Howden, B. P.
10.1101/257915 — genomics — Posted on 2018-01-31
20 Leveraging allele-specific expression to refine fine-mapping for eQTL studies
Zou, J.; Hormozdiari, F.; Jew, B.; Ernst, J.; Sul, J. H.; Eskin, E.
10.1101/257279 — genetics — Posted on 2018-01-31
27 Visualizing structure-mediated interactions in supercoiled DNA molecules
Scott, S.; Xu, Z. M.; Kouzine, F.; Berard, D. J.; Shaheen, C.; Gravel, B.; Saunders, L.; Hofkirchner, A.; Leroux, C.; Laurin, J.; Levens, D.; Benham, C. J.; Leslie, S. R.
10.1101/257949 — biophysics — Posted on 2018-01-31
28 Big data and single cell transcriptomics: implications for ontological representation
Aevermann, B. D.; Novotny, M.; Bakken, T.; Miller, J. A.; Diehl, A. D.; Osumi-Sutherland, D.; Lasken, R. S.; Lein, E.; Scheuermann, R. H.
10.1101/257352 — bioinformatics — Posted on 2018-01-31
30 A bacterial growth law out of steady-state
Korem Kohanim, Y.; Levi, D.; Jona, G.; Bren, A.; Alon, U.
10.1101/257709 — systems biology — Posted on 2018-01-31
31 Dopamine signaling modulates the stability and integration of intrinsic brain networks
Shafiei, G.; Zeighami, Y.; Clark, C. A.; Coull, J. T.; Nagano-Saito, A.; Leyton, M.; Dagher, A.; Misic, B.
10.1101/252528 — neuroscience — Posted on 2018-01-31
32 Learning to read increases the informativeness of distributed ventral temporal responses
Nordt, M.; Gomez, J.; Natu, V.; Jeska, B.; Barnett, M.; Grill-Spector, K.
10.1101/257055 — neuroscience — Posted on 2018-01-31
33 Partially Overlapping Brain Networks for Singing and Cello Playing
Segado, M.; Hollinger, A.; Thibodeau, J.; Penhune, V.; Zatorre, R.
10.1101/257923 — neuroscience — Posted on 2018-01-31
34 Functional wiring of the human medial temporal lobe
Solomon, E. A.; Stein, J. M.; Das, S.; Gorniak, R.; Sperling, M. R.; Worrell, G.; Gross, R. E.; Lega, B.; Jobst, B. C.; Rizzuto, D. S.; Kahana, M. J.
10.1101/257899 — neuroscience — Posted on 2018-01-31
36 Frequent variants in the Japanese population determine quasi-Mendelian inheritance of rare retinal ciliopathy
Nikopoulos, K.; Cisarova, K.; Koskiniemi-Kuendig, H.; Miyake, N.; Farinelli, P.; Quinodoz, M.; Imran, M.; Prunotto, A.; Akiyama, M.; Kamatani, Y.; Terao, C.; Miya, F.; Ikeda, Y.; Ueno, S.; Fuse, N.; Murakami, A.; Terasaki, H.; Sonoda, K.-H.; Ishibashi, T.; Kubo, M.; Cremers, F. P. M.; Matsumoto, N.; Nishiguchi, K. M.; Nakazawa, T.; Rivolta, C.
10.1101/257634 — genomics — Posted on 2018-01-31
37 Genetic basis of transgressive segregation in rice heading phenotypes
Koide, Y.; Uchiyama, T.; Ota, Y.; Sakaguchi, S.; Tezuka, A.; Nagano, A. J.; Ishiguro, S.; Takamure, I.; Kishima, Y.
10.1101/257766 — genetics — Posted on 2018-01-31
41 The age-regulated zinc finger factor ZNF367 is a new modulator of embryonic neurogenesis
Naef, V.; Monticelli, S.; Corsinovi, D.; Mazzetto, M. T.; Cellerino, A.; Ori, M.
10.1101/255919 — developmental biology — Posted on 2018-01-31
43 Cross-type Biomedical Named Entity Recognition with Deep Multi-Task Learning
Wang, X.; Zhang, Y.; Ren, X.; Zhang, Y.; Zitnik, M.; Shang, J.; Langlotz, C.; Han, J.
10.1101/256453 — bioinformatics — Posted on 2018-01-31
44 Nucleosome turnover is sufficient to establish varied histone methylation states
Chory, E. J.; Calarco, J. P.; Hathaway, N. A.; Bell, O.; Neel, D.; Crabtree, G. R.
10.1101/256321 — molecular biology — Posted on 2018-01-31
46 Mechanical mapping of spinal cord development and repair in living zebrafish larvae using Brillouin microscopy
Schlüssler, R.; Möllmert, S.; Abuhattum, S.; Cojoc, G.; Müller, P.; Kim, K.; Möckel, C.; Zimmermann, C.; Czarske, J.; Guck, J.
10.1101/181560 — biophysics — Posted on 2018-01-31
47 Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia
Bansal, V.; Mitjans, M.; Burik, C. A. P.; Karlsson Linner, R.; Okbay, A.; Rietveld, C. A.; Begemann, M.; Bonn, S.; Ripke, S.; Vlaming, R. d.; Nivard, M. G.; Ehrenreich, H.; Koellinger, P. D.
10.1101/114405 — genetics — Posted on 2018-01-31
52 Deep learning using EEG spectrograms for prognosis in idiopathic rapid eye movement behavior disorder (RBD)
Ruffini, G.; Ibanez Soria, D.; Dubreuil, L.; Gagnon, J.-F.; Montplaisir, J.; Soria-Frisch, A.
10.1101/240267 — bioinformatics — Posted on 2018-01-31
55 Spatial Topography of Individual-Specific Cortical Networks Predicts Human Cognition, Personality and Emotion
Kong, R.; Li, J.; Sun, N.; Sabuncu, M. R.; Liu, H.; Schaefer, A.; Zuo, X.-N.; Holmes, A.; Eickhoff, S. B.; Yeo, B. T. T.
10.1101/213041 — neuroscience — Posted on 2018-01-31
56 An empirical, 21st century evaluation of phrenology
Parker Jones, O.; Alfaro-Almagro, F.; Jbabdi, S.
10.1101/243089 — neuroscience — Posted on 2018-01-31
57 Prospects for recurrent neural network models to learn RNA biophysics from high-throughput data
Wu, M. J.; Andreasson, J. O.; Kladwang, W.; Greenleaf, W. J.; Eterna participants, ; Das, R.
10.1101/227611 — biophysics — Posted on 2018-01-31
58 Sinusoidal Voltage Protocols For Rapid Characterisation Of Ion Channel Kinetics
Beattie, K. A.; Hill, A. P.; Bardenet, R.; Cui, Y.; Vandenberg, J. I.; Gavaghan, D. J.; de Boer, T. P.; Mirams, G. R.
10.1101/100677 — biophysics — Posted on 2018-01-31
60 C-BERST: Defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2
Gao, X. D.; Tu, L.-C.; Mir, A.; Rodriguez, T.; Ding, Y.; Leszyk, J.; Dekker, J.; Shaffer, S. A.; Zhu, L. J.; Wolfe, S. A.; Sontheimer, E. J.
10.1101/171819 — molecular biology — Posted on 2018-01-31
61 Genomics-Based Identification of Microorganisms in Human Ocular Body Fluid
Kirstahler, P.; Solborg Bjerrum, S.; Friis-Moller, A.; la Cour, M.; Aarestrup, F. M.; Westh, H.; Pamp, S. J.
10.1101/176529 — microbiology — Posted on 2018-01-31
62 Analysis And Correction Of Compositional Bias In Sparse Sequencing Count Data
Kumar, M. S.; Slud, E. V.; Okrah, K.; Hicks, S. C.; Hannenhalli, S.; Corrada Bravo, H.
10.1101/142851 — genomics — Posted on 2018-01-31
65 Modeling Epidemics in Seed Systems: Sweetpotato in Northern Uganda
Andersen, K.; Buddenhagen, C.; Rachkara, P.; Gibson, R.; Kalule, S.; Phillips, D.; Garrett, K.
10.1101/107359 — ecology — Posted on 2018-01-31
66 Diversity loss selects for altered plant phenotypic responses to local arbuscular mycorrhizal communities
Hahl, T.; van Moorsel, S. J.; Schmid, M. W.; Zuppinger-Dingley, D.; Schmid, B.; Wagg, C.
10.1101/216986 — ecology — Posted on 2018-01-31
67 Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases
Kaiser, F.; Bittrich, S.; Salentin, S.; Leberecht, C.; Haupt, V. J.; Krautwurst, S.; Schroeder, M.; Labudde, D.
10.1101/198846 — bioinformatics — Posted on 2018-01-31
68 Asymmetric Overlap in Neuronal Sensation Constraints Rational Choice in C. elegans
Cohen, D.; Volovich, M.; Zeevi, Y.; Louie, K.; Levy, D. J.; Rechavi, O.
10.1101/257535 — neuroscience — Posted on 2018-01-31
71 ANIMA: Association Network Integration for Multiscale Analysis
Deffur, A.; Wilkinson, R. J.; Mayosi, B. M.; Mulder, N. M.
10.1101/257642 — systems biology — Posted on 2018-01-31
72 Reproducible model development in the Cardiac Electrophysiology Web Lab
Daly, A. C.; Clerx, M.; Beattie, K. A.; Cooper, J.; Gavaghan, D. J.; Mirams, G. R.
10.1101/257683 — systems biology — Posted on 2018-01-31
74 A proposal for a standardized bacterial taxonomy based on genome phylogeny
Parks, D. H.; Chuvochina, M.; Waite, D. W.; Rinke, C.; Skarshewski, A.; Chaumeil, P.-A.; Hugenholtz, P.
10.1101/256800 — microbiology — Posted on 2018-01-31
75 Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain
Ronneau, S.; Caballero-Montes, J.; Mayard, A.; Garcia-Pino, A.; Hallez, R.
10.1101/257592 — microbiology — Posted on 2018-01-31
79 Pcdh18a-positive tip cells instruct notochord formation in zebrafish
Bosze, B.; Mattes, B.; Sinner, C.; Stricker, K.; Gourain, V.; Thumberger, T.; Tlili, S.; Weber, S.; Wittbrodt, J.; Saunders, T. E.; Straehle, U.; Schug, A.; Scholpp, S.
10.1101/257717 — developmental biology — Posted on 2018-01-31
85 Arabidopsis Lunapark proteins are involved in ER cisternae formation
Kriechbaumer, V.; Breeze, E.; Pain, C.; Tolmie, F.; Frigerio, L.; Hawes, C.
10.1101/256743 — plant biology — Posted on 2018-01-31
86 A Single Dose Of Ayahuasca Modulates Salivary Cortisol In Treatment-Resistant Depression
Galvao, A. C. M.; Almeida, R. N.; Silva, E. A. d. S.; de Morais Freire, F. A.; Palhano-Fontes, F.; Onias, H.; Arcoverdee, E.; Maia-de-Oliveira, J. P.; Araujo, D.; Lobao-Soares, B.; Galvao-Coelho, N. L.
10.1101/257238 — physiology — Posted on 2018-01-31
87 Human POMC processing in vitro and in vivo revealed by quantitative peptidomics
Kirwan, P.; Kay, R. G.; Brouwers, B.; Perez, V. H.; Jura, M.; Larraufie, P.; Pembroke, J.; Bartels, T.; White, A.; Gribble, F.; Reimann, F.; Farooqi, I. S.; O'Rahilly, S.; Merkle, F. T.
10.1101/257121 — neuroscience — Posted on 2018-01-31
89 Association of a lincRNA postmortem with suicide by violent means and in vivo with aggressive phenotypes
Punzi, G.; Ursini, G.; Viscanti, G.; Radulescu, E.; Shin, J. H.; Quarto, T.; Catanesi, R.; Blasi, G.; Jaffe, A.; Deep-Soboslay, A.; Hyde, T.; Kleinman, J.; Bertolino, A.; Weinberger, D.
10.1101/257188 — neuroscience — Posted on 2018-01-31
90 The behavioral and neurobiological effects of reduced Brd1 expression in mice are sex-biased and implicate gender dependent dysregulation of nuclear receptor mediated signaling in mental disorders
Rajkumar, A. P.; Qvist, P.; Larsen, S. H.; Lazarus, R.; Pallesen, J.; Nava, N.; Winther, G.; Liebenberg, N.; Paternoster, V.; Fryland, T.; Palmfeldt, J.; Fejgin, K.; Mork, A.; Nyegaard, M.; Pakkenberg, B.; Didriksen, M.; Nyengaard, J. R.; Wegener, G.; Mors, O.; Christensen, J. H.; Borglum, A. D.
10.1101/257170 — neuroscience — Posted on 2018-01-31
91 Motor Cortex Encodes A Value Function Consistent With Reinforcement Learning
Tarigoppula, V. S. A.; Choi, J. S.; Hessburg, J. H.; McNiel, D. B.; Marsh, B. T.; Francis, J. T.
10.1101/257337 — neuroscience — Posted on 2018-01-31
92 Anatomical, Physiological, and Functional Heterogeneity of the Dorsal Raphe Serotonin System
Ren, J.; Friedmann, D.; Xiong, J.; Liu, C. D.; DeLoach, K. E.; Ran, C.; Pu, A.; Sun, Y.; Weissbourd, B.; Neve, R. L.; Horowitz, M.; Luo, L.
10.1101/257378 — neuroscience — Posted on 2018-01-31
95 The plasma miR-122 basal levels respond to circulating catecholamine in rats
Peng, X.; Li, Q.; Lu, S.; He, X.; Yu, S.; Zhang, Z.; Xu, G.; Li, L.; Yang, T.; Zhu, J.; Zhu, W.; Wu, Z.; Luo, D.; Zhu, J.; Xu, B.; Huang, J.; Yin, H.; Xu, K.
10.1101/257402 — molecular biology — Posted on 2018-01-31
96 N6-methyladenosine Binding Proteins Negatively Regulate HIV-1 Infectivity and Viral Production
Lu, W.; Tirumuru, N.; Koneru, P. C.; Liu, C.; Kvaratskhelia, M.; He, C.; Wu, L.
10.1101/257410 — microbiology — Posted on 2018-01-31
97 Ferroptosis-like signaling facilitates a potent innate defense against Plasmodium infection
Kain, H. S.; Arang, N.; Glennon, E.; Douglass, A. N.; Dudgeon, D. R.; Johnson, J. S.; Aderem, A.; Kaushansky, A.
10.1101/257287 — microbiology — Posted on 2018-01-31
100 A Gender-Dependent Molecular Switch of Inflammation via MyD88/Estrogen Receptor-alpha Interaction
El Sabeh, R.; Bonnet, M.; Le Corf, K.; Lang, K.; Kfoury, A.; Badran, B.; Hussein, N.; Virard, F.; Treilleux, I.; Le Romancer, M.; Lebecque, S.; Manie, S.; Coste, I.; Renno, T.
10.1101/255778 — immunology — Posted on 2018-01-31
102 DNA Topoisomerase I differentially modulates R-loops across the human genome
Manzo, S.; Hartono, S. R.; Sanz, L.; De Biasi, S.; Cossarizza, A.; Capranico, G.; Chedin, F.
10.1101/257303 — genomics — Posted on 2018-01-31
103 Next generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM
Jia, Y.; Xu, R.-G.; Ren, X.; Ewen-Campen, B.; Rajakumar, R.; Zirin, J.; Yang-Zhou, D.; Zhao, R.; Wang, F.; Mao, D.; Peng, P.; Qiao, H.-H.; Wang, X.; Liu, L.-P.; Xu, B.; Ji, J.-Y.; Lu, Q.; Sun, J.; Perrimon, N.; Ni, J.-Q.
10.1101/252031 — genetics — Posted on 2018-01-31
104 Bayesian model comparison for rare variant association studies of multiple phenotypes
DeBoever, C.; Aguirre, M.; Tanigawa, Y.; Spencer, C. C. A.; Poterba, T.; Daly, M. J.; Pirinen, M.; Rivas, M. A.
10.1101/257162 — genetics — Posted on 2018-01-31
106 Predatory Behavior is Primary Predictor of Movement of Wildland-Urban Cougars
Buderman, F. E.; Hooten, M. B.; Alldredge, M.; Hanks, E. M.; Ivan, J. S.
10.1101/257295 — ecology — Posted on 2018-01-31
112 Structural and histone binding studies of the chromo barrel domain of TIP60
Zhang, Y.; Lei, M.; Liang, X.; Loppnau, P.; Li, Y.; Min, J.; Liu, Y.
10.1101/257485 — biochemistry — Posted on 2018-01-31
113 Crystal structure of chromo barrel domain of RBBP1
Lei, M.; Feng, Y.; Zhou, M.; Yang, Y.; Loppnau, P.; Li, Y.; Yang, Y.; Liu, Y.
10.1101/257527 — biochemistry — Posted on 2018-01-31
120 An Epiblast Stem Cell derived multipotent progenitor population for axial extension
Edri, S.; Hayward, P.; Baillie-Johnson, P.; Steventon, B.; Martinez Arias, A.
10.1101/242461 — developmental biology — Posted on 2018-01-30
122 Learning a neural response metric for retinal prosthesis
Shah, N. P.; Madugula, S.; Chichilnisky, E. J.; Shlens, J.; Singer, Y.
10.1101/226530 — neuroscience — Posted on 2018-01-30
125 Conditional upregulation of KCC2 selectively enhances neuronal inhibition during seizures
Goulton, C. S.; Watanabe, M.; Cheung, D. L.; Wang, K. W.; Oba, T.; Khoshaba, A.; Lai, D.; Inada, H.; Eto, K.; Nakamura, K.; Power, J. M.; Lewis, T. M.; Housley, G. D.; Wake, H.; Nabekura, J.; Moorhouse, A. J.
10.1101/253831 — neuroscience — Posted on 2018-01-30
126 Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoires
Zhang, W.; Li, X.; Wang, L.; Deng, J.; Lin, L.; Tian, L.; Wu, J.; Yang, H.; Wang, J.; Qiu, P.; Fu, T.-M.; Saksena, N. K.; Wang, I.-M.; Liu, X.
10.1101/254599 — immunology — Posted on 2018-01-30
127 Genome-wide Analysis of Insomnia (N=1,331,010) Identifies Novel Loci and Functional Pathways
Jansen, P. R.; Watanabe, K.; Stringer, S.; Skene, N.; Bryois, J.; Hammerschlag, A. R.; de Leeuw, C. A.; Benjamins, J.; Munoz-Manchado, A. B.; Nagel, M.; Savage, J. E.; Tiemeier, H.; White, T.; Tung, J. Y.; Hinds, D. A.; Vacic, V.; Sullivan, P. F.; van der Sluis, S.; Polderman, T. J.; Smit, A. B.; Hjerling-Leffler, J.; van Someren, E. J.; Posthuma, D.
10.1101/214973 — genetics — Posted on 2018-01-30
131 Sleep problems are associated with hypersensitivity to touch in children with autism
Tzischinsky, O.; Meiri, G.; Manelis, L.; Bar-Sinai, A.; Fluser, H.; Michaelovski, A.; Zivan, O.; Ilan, M.; Faroy, M.; Menashe, I.; Dinstein, I.
10.1101/255323 — neuroscience — Posted on 2018-01-30
132 Stability of association between Arabidopsis thaliana and Pseudomonas pathogens over evolutionary time scales
Karasov, T. L.; Almario, J.; Friedemann, C.; Ding, W.; Giolai, M.; Heavens, D.; Kersten, S.; Lundberg, D. S.; Neumann, M.; Regalado, J.; Neher, R. A.; Kemen, E.; Weigel, D.
10.1101/241760 — microbiology — Posted on 2018-01-30
133 Is IκBζ constitutively expressed in mammalian airway epithelium?
Sundaram, K.; Mitra, S.; Jaynes, F.; Lorscheid, S.; Steiner, H.; Flechtner, A.; Sarkar, A.; Shilo, K.; Boyaka, P. N.; Schulze-Osthoff, K.; Wewers, M. D.
10.1101/255331 — immunology — Posted on 2018-01-30
136 Inherited DNA Repair Defects in Colorectal Cancer
AlDubayan, S.; Giannakis, M.; Moore, N.; Han, G. C.; Reardon, B.; Hamada, T.; Jasmine, X.; Nishihara, R.; Qian, Z.; Yurgelun, M.; Syngal, S.; Garraway, L.; Ogino, S.; Fuchs, C.; Van Allen, E.
10.1101/256917 — genetics — Posted on 2018-01-30
138 Hematopoietic stem cells differentiate into restricted myeloid progenitors before cell division
Grinenko, T.; Eugster, A.; Thielecke, L.; Ramasz, B.; Krueger, A.; Dietz, S.; Glauche, I.; Gerbaulet, A.; von Bonin, M.; Basak, O.; Clevers, H.; Chavakis, T.; Wielockx, B.
10.1101/256024 — cell biology — Posted on 2018-01-30
139 TMEM16F activation by Ca2+ triggers plasmalemma expansion and directs PD-1 trafficking
Bricogne, C.; Fine, M.; Pereira, P. M.; Wang, Y.; Sung, J.; Tijani, M.; Henriques, R.; Collins, M. K.; Hilgemann, D.
10.1101/249227 — cell biology — Posted on 2018-01-30
142 Label-free assessment of red blood cell storage lesions by deep learning
Doan, M.; Sebastian, J. A.; Pinto, P. N.; McQuin, C.; Goodman, A.; Wolkenhauer, O.; Parsons, M. J.; Acker, J. P.; Rees, P.; Hennig, H.; Kolios, M. C.; Carpenter, A. E.
10.1101/256180 — bioinformatics — Posted on 2018-01-30
143 Ontology-based validation and identification of regulatory phenotypes
Kulmanov, M.; Schofield, P. N.; Gkoutos, G. V.; Hoehndorf, R.
10.1101/256529 — bioinformatics — Posted on 2018-01-30
146 Social behavior and anxiety contribute to nicotine self-administration in adolescent outbred rats
Wang, T.; Han, W.; Chitre, A.; Polesskaya, O.; Solberg Woods, L. C.; Palmer, A. A.; Chen, H.
10.1101/257097 — animal behavior and cognition — Posted on 2018-01-30
152 A proposal for a standardized bacterial taxonomy based on genome phylogeny
Parks, D. H.; Chuvochina, M.; Waite, D. W.; Rinke, C.; Skarshewski, A.; Chaumeil, P.-A.; Hugenholtz, P.
10.1101/256800 — microbiology — Posted on 2018-01-30
153 Detection and removal of barcode swapping in single-cell RNA-seq data
Griffiths, J. A.; Richard, A. C.; Bach, K.; Lun, A. T. L.; Marioni, J. C.
10.1101/177048 — genomics — Posted on 2018-01-30
155 ECM cross-linking regulates invadopodia dynamics
Esmaeili Pourfarhangi, K.; Bergman, A.; Gligorijevic, B.
10.1101/198580 — cancer biology — Posted on 2018-01-30
159 Efficient enrichment cloning of TAL effector genes from Xanthomonas
Tran, T. T.; Doucoure, H.; Hutin, M.; Szurek, B.; Cunnac, S.; Koebnik, R.
10.1101/256057 — microbiology — Posted on 2018-01-30
163 DNA methylation mediates genetic liability to non-syndromic cleft lip/palate
Howe, L. J.; Richardson, T. G.; Arathimos, R.; Alvizi, L.; Passos-Bueno, M.-R.; Stanier, P.; Nohr, E.; Ludwig, K. U.; Mangold, E.; Knapp, M.; Stergiakouli, E.; St Pourcain, B.; Davey Smith, G.; Sandy, J.; Relton, C. L.; Lewis, S. J.; Hemani, G.; Sharp, G. C.
10.1101/256842 — genetics — Posted on 2018-01-30
166 Mind-wandering in people with hippocampal damage
McCormick, C.; Rosenthal, C. R.; Miller, T. D.; Maguire, E.
10.1101/159681 — neuroscience — Posted on 2018-01-30
167 A probabilistic approach to discovering dynamic full-brain functional connectivity patterns
Manning, J. R.; Zhu, X.; Willke, T.; Ranganath, R.; Stachenfeld, K.; Hasson, U.; Blei, D. M.; Norman, K. A.
10.1101/106690 — neuroscience — Posted on 2018-01-30
169 Integration of single-cell RNA-seq data into metabolic models to characterize tumour cell populations
Damiani, C.; Maspero, D.; Di Filippo, M.; Colombo, R.; Pescini, D.; Graudenzi, A.; Westerhof, H. V.; Alberghina, L.; Vanoni, M. E.; Mauri, G.
10.1101/256644 — systems biology — Posted on 2018-01-30
170 Crop domestication and pathogen virulence: Interactions of tomato and Botrytis genetic diversity
Soltis, N. E.; Atwell, S.; Shi, G.; Fordyce, R.; Gwinner, R.; Gao, D.; Shafi, A.; Kliebenstein, D.
10.1101/255992 — plant biology — Posted on 2018-01-30
178 CozEa and CozEb play overlapping and essential roles in controlling cell division in Staphylococcus aureus
Stamsas, G. A.; Myrbraten, I.; Straume, D.; Salehian, Z.; Veening, J.-W.; Havarstein, L. S.; Kjos, M.
10.1101/256560 — microbiology — Posted on 2018-01-30
179 The contribution of non-canonical splicing mutations to severe dominant developmental disorders
Lord, J.; Gallone, G.; Short, P. J.; McRae, J. F.; Ironfield, H.; Wynn, E. H.; Gerety, S. S.; He, L.; Kerr, B.; Johnson, D. S.; McCann, E.; Kinning, E.; Flinter, F.; Temple, I. K.; Clayton-Smith, J.; McEntagart, M.; Lynch, S. A.; Joss, S.; Douzgou, S.; Dabir, T.; Clowes, V.; McConnell, V. P. M.; Lam, W.; Wright, C. F.; FitzPatrick, D. R.; Firth, H. V.; Barrett, J. C.; Hurles, M. E.; on behalf of the DDD study,
10.1101/256636 — genetics — Posted on 2018-01-30
181 Limb bone scaling in hopping diprotodonts and quadrupedal artiodactyls
Doube, M.; Felder, A. A.; Chua, M. Y.; Lodhia, K.; Kłosowski, M. M.; Hutchinson, J. R.; Shefelbine, S. J.
10.1101/256768 — evolutionary biology — Posted on 2018-01-30
182 Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart
Sanchez-Iranzo, H.; Galardi-Castilla, M.; Sanz-Morejon, A.; Gonzalez-Rosa, J. M.; Costa, R.; Ernst, A.; Sainz de Aja, J.; Langa, J.; Mercader, N.
10.1101/254748 — developmental biology — Posted on 2018-01-30
185 Bend-Induced Twist Waves and the Structure of Nucleosomal DNA
Skoruppa, E.; Nomidis, S. K.; Marko, J. F.; Carlon, E.
10.1101/256818 — biophysics — Posted on 2018-01-30
189 Estimating the statistical performance of different approaches to meta-analysis of data from animal studies in identifying the impact of aspects of study design
Wang, Q.; Liao, J.; Hair, K.; Bannach-Brown, A.; Bahor, Z.; Currie, G. L.; McCann, S. K.; Howells, D. W.; Sena, E. S.; Macleod, M. R.
10.1101/256776 — bioinformatics — Posted on 2018-01-30
192 FlowPot axenic plant growth system for microbiota research
Kremer, J. M.; Paasch, B. C.; Rhodes, D.; Thireault, C.; Froehlich, J. E.; Schulze-Lefert, P.; Tiedje, J. M.; He, S. Y.
10.1101/254953 — plant biology — Posted on 2018-01-30
194 Antimalarial pantothenamide metabolites target acetyl-CoA synthesis in Plasmodium falciparum
Allman, E. L.; Beuckens-Schortinghuis, C. A.; Blaauw, R. H.; Bolscher, J. M.; Bonnert, R.; Botman, P. N.; Campo, B.; Dechering, K. J.; Fischli, C.; Hermkens, P. H.; Jockowski, S.; Jansen, P. A.; Kooij, T. W.; Koolen, K. M.; Miller, K.; Llinas, M.; Pett, H.; Reeves, S.; Rutjes, F. P.; Sauerwein, R.; Sax, S.; Schalkwijk, J.; Scheurer, C.; Trevitt, G.; Vos, M. W.; De Vries, L. E.; Wittlin, S.; Josling, G.
10.1101/256669 — pharmacology and toxicology — Posted on 2018-01-30
195 Combinatorial Tissue Engineering Partially Restores Function after Spinal Cord Injury
Hakim, J.; Rodysill, B.; Chen, B. K.; Schmeichel, A.; Yaszemski, M. J.; Windebank, A.; Madigan, N.
10.1101/254821 — neuroscience — Posted on 2018-01-30
201 Evolution at two time frames: polymorphisms from an ancient singular divergence event fuel contemporary parallel evolution
Van Belleghem, S.; Vangestel, C.; De Wolf, K.; De Corte, Z.; Moest, M.; Rastas, P.; De Meester, L.; Hendrickx, F.
10.1101/255554 — evolutionary biology — Posted on 2018-01-30
210 Sleep problems are associated with hypersensitivity to touch in children with autism
Tzischinsky, O.; Meiri, G.; Manelis, L.; Bar-Sinai, A.; Fluser, H.; Michaelovski, A.; Zivan, O.; Ilan, M.; Faroy, M.; Menashe, I.; Dinstein, I.
10.1101/255323 — neuroscience — Posted on 2018-01-30
213 A high-quality sequence of Rosa chinensis to elucidate genome structure and ornamental traits
Hibrand, L.; Ruttink, T.; Hamama, L.; Kirov, I.; Lakhwani, D.; Zhou, N.-N.; Bourke, P.; Daccord, N.; Leus, L.; Schulz, D.; Van deGeest, H.; Hesselink, T.; Van Laere, K.; Balzergue, S.; Thouroude, T.; Chastellier, A.; Jeauffre, J.; Voisine, L.; Gaillard, S.; Borm, T.; Arens, P.; Voorrips, R.; Maliepaard, C.; Neu, E.; Linde, M.; Le Paslier, M.-C.; Berard, A.; Bounon, R.; Clotault, J.; Choisne, N.; Quesneville, H.; Kawamura, K.; Aubourg, S.; Sakr, S.; Smulder, R.; Schijlen, E.; Bucher, E.; Debener, T.; De Riek, J.; Foucher, F.
10.1101/254102 — genomics — Posted on 2018-01-30
218 DREAM-Yara: An implementation of an exact read mapper for very large databases
Dadi, T. H.; Piro, V.; Andrusch, A.; Seiler, E.; Renard, B.; Reinert, K.
10.1101/256354 — bioinformatics — Posted on 2018-01-30
219 A robot-based gait training therapy for pediatric population with Cerebral Palsy: goal setting, proposal and preliminary clinical implementation
Bayon, C.; Martin-Lorenzo, T.; Moral-Saiz, B.; Ramirez, O.; Perez-Somarriba, A.; Lerma-Lara, S.; Martinez-Caballero, I.; Rocon, E.
10.1101/255448 — bioengineering — Posted on 2018-01-30
221 iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
Oikonomidi, I.; Burbridge, E.; Cavadas, M.; Sullivan, G.; Clancy, D.; Collis, B.; Brezinova, J.; Humpolickova, J.; Hu, T.; Bileck, A.; Gerner, C.; Bolado, A.; von Kriegsheim, A.; Strisovsky, K.; Martin, S. J.; Adrain, C.
10.1101/255745 — biochemistry — Posted on 2018-01-30
222 Opposing effects of population density and stress on Escherichia coli mutation rate
Krasovec, R.; Richards, H.; Gifford, D. R.; Belavkin, R. V.; Channon, A.; Aston, E.; McBain, A. J.; Knight, C. G.
10.1101/256305 — evolutionary biology — Posted on 2018-01-30
227 When metabolism meets physiology: Harvey and Harvetta
Thiele, I.; Sahoo, S.; Heinken, A.; Heirendt, L.; Aurich, M. K.; Noronha, A.; Fleming, R. M. T.
10.1101/255885 — systems biology — Posted on 2018-01-29
230 Immune cellular homeostasis in early life is determined by genetic variants of cellular production and turnover
Dubovik, T.; Starosvetsky, E.; LeRoy, B.; Normand, R.; Admon, Y.; Alpert, A.; Ofran, Y.; G'Sell, M.; Shen-Orr, S. S.
10.1101/256073 — immunology — Posted on 2018-01-29
231 On the design of CRISPR-based single cell molecular screens
Hill, A. J.; McFaline-Figueroa, J. L.; Starita, L. M.; Gasperini, M. J.; Matreyek, K. A.; Packer, J.; Jackson, D.; Shendure, J.; Trapnell, C.
10.1101/254334 — genomics — Posted on 2018-01-29
234 Massively parallel dissection of human accelerated regions in human and chimpanzee neural progenitors
Ryu, H.; Inoue, F.; Whalen, S.; Williams, A.; Kircher, M.; Martin, B.; Alvarado, B.; Samee, M. A. H.; Keough, K.; Thomas, S.; Kriegstein, A.; Shendure, J.; Pollen, A.; Ahituv, N.; Pollard, K.
10.1101/256313 — evolutionary biology — Posted on 2018-01-29
235 A role for RNA and DNA:RNA hybrids in the modulation of DNA repair by homologous recombination
D'Alessandro, G.; Adamowicz, M.; Whelan, D.; Howard, S. M.; Jones-Weinert, C. W.; Matti, V.; Rothenberg, E.; Cejka, P.; d'Adda di Fagagna, F.
10.1101/255976 — cell biology — Posted on 2018-01-29
236 Hematopoietic stem cells differentiate into restricted myeloid progenitors before cell division
Grinenko, T.; Eugster, A.; Thielecke, L.; Ramazs, B.; Krueger, A.; Dietz, S.; Glauche, I.; Gerbaulet, A.; von Bonin, M.; Basak, O.; Clevers, H.; Chavakis, T.; Weilockx, B.
10.1101/256024 — cell biology — Posted on 2018-01-29
237 Targeting the SUMO pathway primes all-trans-retinoic acid-induced differentiation of non promyelocytic Acute Myeloid Leukemias
Baik, H.; Boulanger, M.; Hosseini, M.; Kowalczyk, J.; Zaghdoudi, S.; Salem, T.; Sarry, J.-E.; Hicheri, Y.; Cartron, G.; Piechaczyk, M.; bossis, g.
10.1101/254946 — cancer biology — Posted on 2018-01-29
238 Genome-wide identification of CDC34 that stabilizes EGFR and promotes lung carcinogenesis
Zhao, X.-C.; Wang, G.-Z.; Zhou, Y.-C.; Liu, J.; Ma, L.; Zhang, C.; Zhang, D.-L.; Gao, S.-H.; Qu, L.-W.; Zhang, B.; Wang, C.-L.; Huang, Y.-C.; Chen, L.; Zhou, G.-B.
10.1101/255844 — cancer biology — Posted on 2018-01-29
243 Artefactual formation of pyruvate from in-source conversion of lactate
Snyder, N. W.; Trefely, S.; Mesaros, C.; Xu, P.; Doan, M.; Jiang, H.; Altinok, O.; Orynbayeva, Z.
10.1101/256271 — biochemistry — Posted on 2018-01-29
247 PET Brain imaging of α7-nAChR with ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia
Wong, D. F.; Kuwabara, H.; Horti, A. G.; Roberts, J.; Nandi, A.; Cascella, N.; Brasic, J. R.; Weerts, E.; Kitzmiller, K.; Phan, J. A.; Gapasin, L.; Sawa, A.; Valentine, H.; Wand, G.; George, N.; McDonald, M.; Kem, W.; Freedman, R.; Gjedde, A.
10.1101/245118 — neuroscience — Posted on 2018-01-29
249 Predicting E. coli concentrations using limited qPCR deployments at Chicago beaches
Lucius, N.; Rose, K.; Osborn, C.; Sweeney, M. E.; Chesak, R.; Little, D. Y.; Beslow, S.; Schenk, T.
10.1101/250480 — bioinformatics — Posted on 2018-01-29
251 BDNF and Tau as biomarkers of severity in Multiple Sclerosis
Islas-Hernandez, A.; Aguilar-Talamantes, H. S.; Bertado-Cortes, B.; Mejia-delCastillo, G. d. J.; Carrera-Pineda, R.; Cuevas-Garcia, C. F.; Garcia-delaTorre, P.
10.1101/236158 — neuroscience — Posted on 2018-01-29
252 Increasing tolerance of hospital Enterococcus faecium to hand-wash alcohols
Pidot, S. J.; Gao, W.; Buultjens, A. H.; Monk, I. R.; Guerillot, R.; Carter, G. P.; Lee, J. Y. H.; Lam, M. M. C.; Ballard, S. A.; Grayson, M. L.; Mahony, A. A.; Grabsch, E. A.; Kotsanas, D.; Korman, T.; Coombs, G. W.; Robinson, J. O.; Goncalves da Silva, A.; Seemann, T.; Howden, B. P.; Johnson, P. D. R.; Stinear, T. P.
10.1101/053728 — microbiology — Posted on 2018-01-29
254 Allele-specific CRISPR/Cas9 genome editing of the single-base P23H mutation for rhodopsin associated dominant retinitis pigmentosa
Li, P.; Kleinstiver, B. P.; Leon, M. Y.; Prew, M. S.; Navarro-Gomez, D.; Greenwald, S. H.; Pierce, E. A.; Joung, J. K.; Liu, Q.
10.1101/197962 — genetics — Posted on 2018-01-29
256 Continuous interdomain orientation distributions reveal components of binding thermodynamics
Qi, Y.; Martin, J. W.; Barb, A. W.; Thelot, F.; Yan, A.; Donald, B. R.; Oas, T. G.
10.1101/200238 — biophysics — Posted on 2018-01-29
257 Deep learning using EEG spectrograms for prognosis in idiopathic rapid eye movement behavior disorder (RBD)
Ruffini, G.; Ibanez Soria, D.; Dubreuil, L.; Gagnon, J.-F.; Montplaisir, J.; Soria-Frisch, A.
10.1101/240267 — bioinformatics — Posted on 2018-01-29
258 COSSMO: Predicting Competitive Alternative Splice Site Selection using Deep Learning
Bretschneider, H.; Gandhi, S.; Zuberi, K.; Deshwar, A. G.; Frey, B. J.
10.1101/255257 — bioinformatics — Posted on 2018-01-29
260 Causal explanation of individual differences in human sensorimotor memory formation
Petitet, P.; O'Reilly, J. X.; Goncalves, A. M.; Salvan, P.; Kitazawa, S.; Johansen-Berg, H.; O'Shea, J.
10.1101/255091 — neuroscience — Posted on 2018-01-29
262 Systematic detection of amino acid substitutions in proteome reveals a mechanistic basis of ribosome errors
Mordret, E.; Yehonadav, A.; Barnabas, G. D.; Cox, J.; Dahan, O.; Geiger, T.; Lindner, A. B.; Pilpel, Y.
10.1101/255943 — systems biology — Posted on 2018-01-29
263 Is IκBζ constitutively expressed in mammalian airway epithelium?
Sundaram, K.; Mitra, S.; Jaynes, F.; Lorscheid, S.; Steiner, H.; Flechtner, A.; Sarkar, A.; Shilo, K.; Boyaka, P. N.; Schulze-Osthoff, K.; Wewers, M. D.
10.1101/255331 — immunology — Posted on 2018-01-29
264 Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology
Howe, L. J.; Lee, M. K.; Sharp, G. C.; Davey Smith, G.; St Pourcain, B.; Shaffer, J. R.; Marazita, M. L.; Feingold, E.; Zhurov, A.; Stergiakouli, E.; Sandy, J.; Richmond, S.; Weinberg, S. M.; Hemani, G.; Lewis, S. J.
10.1101/255901 — genetics — Posted on 2018-01-29
268 Tracing the Ancestry of Operons in Bacteria
Nguyen, H. N.; Jain, A.; Eulenstein, O.; Friedberg, I.
10.1101/212886 — evolutionary biology — Posted on 2018-01-29
275 Individual differences in functional brain connectivity predict temporal discounting preference in the transition to adolescence
Anandakumar, J.; Mills, K.; Earl, E.; Irwin, L.; Miranda-Dominguez, O.; Demeter, D. V.; Walton-Weston, A.; Karalunas, S.; Nigg, J.; Fair, D. A.
10.1101/255679 — neuroscience — Posted on 2018-01-29
279 Genomic copy-number loss is rescued by self-limiting production of DNA circles
Mansisidor, A. R.; Molinar, T.; Srivastava, P.; Blitzblau, H.; Klein, H.; Hochwagen, A.
10.1101/255471 — molecular biology — Posted on 2018-01-29
280 Cotranslational folding of a pentarepeat β-helix protein
Notari, L.; Martinez-Carranza, M.; Stenmark, P.; Von Heijne, G.
10.1101/255810 — molecular biology — Posted on 2018-01-29
283 Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoires
Zhang, W.; Li, X.; Wang, L.; Deng, J.; Lin, L.; Tian, L.; Wu, J.; Yang, H.; Wang, J.; Qiu, P.; Fu, T.-M.; Saksena, N. K.; Wang, I.-M.; Liu, X.
10.1101/254599 — immunology — Posted on 2018-01-29
284 Gut bacterial metabolite Urolithin A (UA) mitigates Ca2+ 1 entry inT cells by regulating miR-10a-5p
Zhang, S.; Maghout, T.; Cao, H.; Pelzl, L.; Salkere, M.; Cheng, A.; Lang, F.; Singh, Y.
10.1101/255588 — immunology — Posted on 2018-01-29
286 Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements
Andermann, T.; Fernandes, A. M.; Olsson, U.; Topel, M.; Pfeil, B.; Oxelman, B.; Aleixo, A.; Faircloth, B. C.; Antonelli, A.
10.1101/255752 — evolutionary biology — Posted on 2018-01-29
287 Coexistence of multiple endemic and pandemic lineages of the rice blast pathogen
Gladieux, P.; Ravel, S.; Rieux, A.; Cros-Arteil, S.; Adreit, H.; Milazzo, J.; Thierry, M.; Fournier, E.; Terauchi, R.; Tharreau, D.
10.1101/179895 — evolutionary biology — Posted on 2018-01-29
289 Halogen-aromatic π-interactions modulate inhibitor residence time
Heroven, C.; Georgi, V.; Ganotra, G. K.; Brennan, P. E.; Wolfreys, F.; Wade, R. C.; Fernandez-Montalvan, A. E.; Chaikuad, A.; Knapp, S.
10.1101/255513 — biophysics — Posted on 2018-01-29
294 Environmental adaptation of olfactory receptor distributions
Tesileanu, T.; Cocco, S.; Monasson, R.; Balasubramanian, V.
10.1101/255547 — neuroscience — Posted on 2018-01-29
295 Neural circuitry of a polycystin-mediated hydrodynamic startle response for predator avoidance
Bezares-Calderon, L. A.; Berger, J.; Jasek, S.; Veraszto, C.; Mendes, S.; Guehmann, M.; Almeda, R.; Shahidi, R.; Jekely, G.
10.1101/255570 — neuroscience — Posted on 2018-01-29
299 An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein
Dewari, P. S.; Southgate, B.; Mccarten, K.; Monogarov, G.; O'Duibhir, E.; Quinn, N.; Tyrer, A.; Plumb, C.; Blin, C.; Finch, R.; Bressan, R. B.; Morrison, G.; Jacobi, A. M.; Behlke, M. A.; von Kriegsheim, A.; Tomlinson, S.; Krijgsveld, J.; Pollard, S. M.
10.1101/255737 — cell biology — Posted on 2018-01-29
300 Membrane bending energy and tension govern mitochondrial division
Carlini, L.; Mahecic, D.; Kleele, T.; Roux, A.; Manley, S.
10.1101/255356 — biophysics — Posted on 2018-01-29
301 Phylodynamic model adequacy using posterior predictive simulations
Duchene, S.; Bouckaert, R.; Duchene, D. A.; Stadler, T.; Drummond, A. J.
10.1101/255596 — bioinformatics — Posted on 2018-01-29
302 Sub-voxel light-sheet microscopy for high-resolution, high-throughput volumetric imaging of large biomedical specimens
Fei, P.; Nie, J.; Lee, J.; Ding, Y.; Li, S.; Yu, Z.; Zhang, H.; Hagiwara, M.; Yu, T.; Segura, T.; Ho, C.-M.; Zhu, D.; Hsiai, T. K.
10.1101/255695 — bioengineering — Posted on 2018-01-29
305 Gene composition as a potential barrier to large recombinations in the bacterial pathogen Klebsiella pneumoniae
Comandatore, F.; Sassera, D.; Bayliss, S. C.; Scaltriti, E.; Gaiarsa, S.; Cao, X.; Gales, A.; Saito, R.; Pongolini, S.; Brisse, S.; Feil, E.; Bandi, C.
10.1101/255349 — evolutionary biology — Posted on 2018-01-28
306 Multicolor single particle reconstruction of protein complexes
Sieben, C.; Banterle, N.; Douglass, K.; Gonczy, P.; Manley, S.
10.1101/255364 — cell biology — Posted on 2018-01-28
308 Unbiased construction of a temporally consistent morphological atlas of neonatal brain development
Schuh, A.; Makropoulos, A.; Robinson, E. C.; Cordero-Grande, L.; Hughes, E.; Hutter, J.; Price, A. N.; Murgasova, M.; Teixeira, R. P. A. G.; Tusor, N.; Steinweg, J. K.; Victor, S.; Rutherford, M. A.; Hajnal, J. V.; Edwards, A. D.; Rueckert, D.
10.1101/251512 — neuroscience — Posted on 2018-01-28
311 Increased prefrontal activity with aging reflects nonspecific neural responses rather than compensation
Morcom, A. M.; Cambridge Centre for Ageing and Neuroscience (Cam-CAN), ; Henson, R. N.
10.1101/156935 — neuroscience — Posted on 2018-01-28
314 Interrogation of human hematopoiesis at single-cell and single-variant resolution
Lareau, C. A.; Ulirsch, J. C.; Bao, E. L.; Ludwig, L. S.; Guo, M. H.; Benner, C.; Satpathy, A. T.; Salem, R.; Hirschhorn, J. N.; Finucane, H. K.; Aryee, M. J.; Buenrostro, J. D.; Sankaran, V. G.
10.1101/255224 — genetics — Posted on 2018-01-28
315 Valection: Design Optimization for Validation and Verification Studies
Cooper, C. I.; Yao, D.; Sendorek, D. H.; Yamaguchi, T. N.; P'ng, C.; Houlahan, K. E.; Caloian, C.; Fraser, M.; SMC-DNA Challenge Participants, ; Ellrott, K.; Margolin, A. A.; Bristow, R. G.; Stuart, J. M.; Boutros, P. C.
10.1101/254839 — bioinformatics — Posted on 2018-01-28
319 Analysis of proteins in computational models of synaptic plasticity
Heil, K. F.; Wysocka, E.; Sorokina, O.; Hellgren Kotaleski, J.; Simpson, T. I.; Armstrong, J. D.; Sterratt, D. C.
10.1101/254094 — neuroscience — Posted on 2018-01-28
320 The Juicebox Assembly Tools module facilitates de novo assembly of mammalian genomes with chromosome-length scaffolds for under $1000
Dudchenko, O.; Shamim, M. S.; Batra, S.; Durand, N. C.; Musial, N. T.; Mostofa, R.; Pham, M.; Glenn St Hilaire, B.; Yao, W.; Stamenova, E.; Hoeger, M.; Nyquist, S. K.; Korchina, V.; Pletch, K.; Flanagan, J. P.; Tomaszewicz, A.; McAloose, D.; Perez Estrada, C.; Novak, B. J.; Omer, A. D.; Aiden, E. L.
10.1101/254797 — genomics — Posted on 2018-01-28
321 Parp3 promotes long-range end-joining in murine cells
Layer, J. V.; Cleary, J. P.; Brown, A. J.; Stevenson, K. E.; Morrow, S. N.; Van Scoyk, A.; Blasco, R. B.; Karaca, E.; Meng, F.-L.; Frock, R. L.; Tivey, T.; Kim, S. S.; Fuchs, H.; Chiarle, R.; Alt, F. W.; Roberts, S. A.; Weinstock, D. M.; Day, T.
10.1101/255281 — cancer biology — Posted on 2018-01-28
322 From 1D sequence to 3D chromatin dynamics and cellular functions: a phase separation perspective
Liu, S.; Zhang, L.; Quan, H.; Tian, H.; Meng, L.; Yang, L.; Feng, H.; Gao, Y. Q.
10.1101/255174 — biophysics — Posted on 2018-01-28
328 Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-specific Immune Changes
DiNardo, A. R.; Nishiguchi, T.; Mace, E. M.; Rajapakshe, K.; Mtetwa, G.; Kay, A.; Maphalala, G.; Secor, W. E.; Mejia, R. A.; Coarfa, C.; Bhalla, K. N.; Graviss, E. A.; Orange, J. S.; Makedonas, G.; Mandalakas, A. M.
10.1101/255125 — immunology — Posted on 2018-01-27
329 Metabolic mechanisms of interaction within a defined gut microbiota
Medlock, G. L.; Carey, M. A.; McDuffie, D. G.; Mundy, M. B.; Giallourou, N.; Swann, J. R.; Kolling, G.; Papin, J. A.
10.1101/250860 — microbiology — Posted on 2018-01-27
330 Genomic dissection of Systemic Lupus Erythematosus: Distinct Susceptibility, Activity and Severity Signatures
Panousis, N. I.; Bertsias, G.; Ongen, H.; Gergianaki, I.; Tektonidou, M.; Trachana, M.; Romano-Palumbo, L.; Bielser, D.; Howald, C.; Pamfil, C.; Fanouriakis, A.; Kosmara, D.; Repa, A.; Sidiropoulos, P.; Dermitzakis, E. T.; Boumpas, D. T.
10.1101/255109 — genomics — Posted on 2018-01-27
334 A comprehensive manually-curated Compendium of Bovine Transcription Factors
de Souza, M. M.; Vaquerizas, J. M.; Zerlotini, A.; Geistlinger, L.; Hernandez-Rodriguez, B.; Tizioto, P.; Taylor, J. F.; Rocha, M. I.; Diniz, W. J.; Coutinho, L.; Regitano, L. C. d. A.
10.1101/254011 — genomics — Posted on 2018-01-27
336 Taxonomic identification from metagenomic and metabarcoding data using any genetic marker
Bengtsson-Palme, J.; Richardsson, R. T.; Meola, M.; Wurzbacher, C.; Tremblay, E. D.; Thorell, K.; Kanger, K.; Eriksson, M.; Bilodeau, G. J.; Johnson, R. M.; Hartmann, M.; Nilsson, H.
10.1101/253377 — bioinformatics — Posted on 2018-01-27
338 A strategy to exploit surrogate sire technology in animal breeding programs
Gottardo, P.; Gorjanc, G.; Battagin, M.; Gaynor, C. R.; Jenko, J.; Freixedes, R. R.; Whitelaw, B.; Mileham, A.; Herring, W.; Hickey, J.
10.1101/199893 — genetics — Posted on 2018-01-27
340 Viral diversity is an obligate consideration in CRISPR/Cas9 designs for HIV cure
Roychoudhury, P.; De Silva Feelixge, H.; Reeves, D. B.; Mayer, B. T.; Stone, D.; Schiffer, J. T.; Jerome, K. R.
10.1101/255133 — bioinformatics — Posted on 2018-01-27
342 In vivo clonal analysis reveals spatiotemporal regulation of thalamic nucleogenesis
Wong, S.; Scott, E. P.; Borgenheimer, E.; Freeman, M.; Ming, G.-l.; Wu, Q.-F.; Song, H.; Nakagawa, Y.
10.1101/238964 — neuroscience — Posted on 2018-01-27
345 Linking drug target and pathway activation for effective therapy using multi-task learning
Yang, M.; Simm, J.; Lam, C. C.; Zakeri, P.; van Westen, G. J. P.; Moreau, Y.; Saez-Rodriguez, J.
10.1101/225573 — bioinformatics — Posted on 2018-01-27
346 Hi-TOM: a platform for high-throughput tracking of mutations induced by CRISPR/Cas systems
Liu, Q.; Wang, C.; Jiao, X.; Zhang, H.; Song, L.; Li, Y.; Gao, C.; Wang, K.
10.1101/235903 — bioinformatics — Posted on 2018-01-27
349 Noise-driven Cell Differentiation and the Emergence of Organization
Safdari, H.; Kalirad, A.; Picioreanu, C.; Tusserkani, R.; Goliaei, B.; Sadeghi, M.
10.1101/220525 — developmental biology — Posted on 2018-01-27
353 The anthelmintic niclosamide is a potent TMEM16A antagonist that fully bronchodilates airways
Miner, K.; Liu, B.; Wang, P.; Labitzke, K.; Gaida, K.; Chen, J. J.; Liu, L.; Leith, A.; Elliott, R.; Henckels, K.; Trueblood, E.; Hensley, K.; Xia, X.-Z.; Homann, O.; Bennett, B.; Fiorino, M.; Whoriskey, J.; Escobar, S.; Yu, G.; McGivern, J.; Wong, M.; Born, T. L.; Budelsky, A.; Comeau, M.; Smith, D.; Phillips, J.; Johnston, J. A.; Weikl, K.; Powers, D.; Mohn, D.; Hochheimer, A.; Sullivan, J. K. K.
10.1101/254888 — physiology — Posted on 2018-01-27
354 Inter- and intra-domain functional redundancy in the rumen microbiome during plant biomass degradation
Soellinger, A.; Tveit, A. T.; Poulsen, M.; Noel, S. J.; Bengtsson, M.; Bernhardt, J.; Frydendahl Hellwing, A. L.; Lund, P.; Riedel, K.; Schleper, C.; Hojberg, O.; Urich, T.
10.1101/254672 — microbiology — Posted on 2018-01-27
355 Gut microbiome transition across a lifestyle gradient in Himalaya
Jha, A. R.; Davenport, E. R.; Gautam, Y.; Bhandari, D.; Tandukar, S.; Ng, K.; Holmes, S.; Gautam, G. P.; Sherchand, J. B.; Bustamante, C.; Sonnenburg, J.
10.1101/253450 — microbiology — Posted on 2018-01-27
356 Genetic factors and age are the strongest predictors of humoral immune responses to common pathogens and vaccines
Scepanovic, P.; Alanio, C.; Hammer, C.; Hodel, F.; Bergstedt, J.; Patin, E.; Thorball, C. W.; Chaturvedi, N.; Charbit, B.; Abel, L.; Quintana-Murci, L.; Duffy, D.; Albert, M. L.; Fellay, J.; The Milieu Interieur Consortium,
10.1101/254706 — genomics — Posted on 2018-01-27
357 Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide
Zhivagui, M.; Ardin, M.; Ng, A. W. T.; Churchwell, M.; Pandey, M.; Villar, S.; Cahais, V.; Robitaille, A.; Bouaoun, L.; Heguy, A.; Guyton, k.; Stampfer, M.; McKay, J.; Hollstein, M.; Olivier, M.; Rozen, S.; Beland, F.; Korenjak, M.; Zavadil, J.
10.1101/254664 — genomics — Posted on 2018-01-27
358 Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data Across 27 Tissue Types
Funk, C. C.; Jung, S.; Richards, M. A.; Rodriguez, A.; Shannon, P.; Donovan, R.; Heavner, B.; Chard, K.; Xiao, Y.; Glusman, G.; Erteskin-Taner, N.; Golde, T.; Toga, A.; Hood, L.; Van Horn, J. D.; Kesselman, C.; Foster, I.; Ament, S.; Madduri, R.; Price, N. D.
10.1101/252023 — bioinformatics — Posted on 2018-01-27
367 Microglia inhibition rescues developmental hypofrontality in a mouse model of mental illness
Chini, M.; Lindemann, C.; Poepplau, J. A.; Xu, X.; Ahlbeck, J.; Bitzenhofer, S. H.; Mulert, C.; Hanganu-Opatz, I. L.
10.1101/254656 — neuroscience — Posted on 2018-01-27
369 Truncation and Motif Based Pan-Cancer Analysis Highlights Novel Tumor Suppressing Kinases.
Hudson, A.; Stepehnson, N.; Li, C.; Trotter, E.; Fletcher, A.; Katona, G.; Bieniasz-Krzywiec, P.; Howell, M.; Wirth, C.; Miller, C.; Brognard, J.
10.1101/254813 — cancer biology — Posted on 2018-01-27
370 Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration ofinflammatory immune cells in EGFR mutant lung tumors
Ayeni, D.; Miller, B.; Kuhlmann, A.; Ho, P.-C.; Robles-Oteiza, C.; Gaefele, M.; Levy, S.; de Miguel, F.; Perry, C.; Guan, T.; Zelterman, D.; Homer, R.; Liu, Z.; Kaech, S.; Politi, K.
10.1101/254847 — cancer biology — Posted on 2018-01-27
374 Exposure of zebra mussels to extracorporeal shock waves demonstrates formation of new mineralized tissue inside and outside the focus zone
Sternecker, K.; Geist, J.; Beggel, S.; Dietz-Laursonn, K.; de la Fuente, M.; Frank, H.-G.; Furia, J. P.; Milz, S.; Schmitz, C.
10.1101/254771 — biophysics — Posted on 2018-01-27
376 Identification of novel rare sequence variation underlying heritable pulmonary arterial hypertension
Gräf, S.; Haimel, M.; Bleda, M.; Hadinnapola, C.; Southgate, L.; Li, W.; Hodgson, J.; Liu, B.; Salmon, R. M.; Southwood, M.; UK PAH Cohort Study Consortium, ; NIHR BioResource - Rare Disease Consortium, ; Machado, R. D.; Martin, J. M.; Treacy, C. M.; Yates, K.; Daugherty, L. C.; Shamardina, O.; Whitehorn, D.; Holden, S.; Aldred, M.; Bogaard, H. J.; Church, C.; Coghlan, G.; Condliffe, R.; Corris, P. A.; Danesino, C.; Eyries, M.; Gall, H.; Ghio, S.; Ghofrani, H.-A.; Gibbs, J. S. R.; Girerd, B.; Houweling, A. C.; Howard, L.; Humbert, M.; Kiely, D. G.; Kovacs, G.; MacKenzie Ross, R. V.;
10.1101/185272 — genetics — Posted on 2018-01-26
377 Genetically encoded ratiometric indicators for potassium ion
Shen, Y.; Wu, S.-Y.; Rancic, V.; Qian, Y.; Miyashita, S.-I.; Ballanyi, K.; Campbell, R. E.; Dong, M.
10.1101/254383 — bioengineering — Posted on 2018-01-26
378 Mapping nonapoptotic caspase activity with a transgenic reporter in mice
Nicholls, P.; Pack, T.; Urs, N.; Kumar, S.; Turu, G.; Calabrese, E.; Roberts, W.; Fan, P.; Ostapchenko, V.; Guzman, M.; Beraldo, F.; Prado, V.; Prado, M.; Spasojevic, I.; Snyder, J.; Dzirasa, K.; Johnson, G. A.; Caron, M.
10.1101/196105 — neuroscience — Posted on 2018-01-26
381 Heat shock factor 5 is conserved in vertebrates and essential forspermatogenesis in zebrafish
Orban, L.; Saju, J. M.; Hossain, M. S.; Liew, W. C.; Pradhan, A.; Thevasagayam, N. M.; Anand, A.; Olsson, P.-E.
10.1101/254615 — developmental biology — Posted on 2018-01-26
382 Idiosyncratic, retinotopic bias in face identification modulated by familiarity
Visconti di Oleggio Castello, M.; Taylor, M.; Cavanagh, P.; Gobbini, M. I.
10.1101/253468 — neuroscience — Posted on 2018-01-26
383 Enhancing resolution of natural methylome reprogramming behavior in plants
Sanchez, R.; Yang, X.; Kundariya, H.; Barreras, J. R.; Wamboldt, Y.; Mackenzie, S.
10.1101/252106 — genomics — Posted on 2018-01-26
386 Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in precision-medicine oriented early phase clinical trials
Pedro Torres-Ayuso, ; Sahoo, S.; Galvin, M.; Leong, H. S.; Frese, K. K.; Cook, N.; Hughes, A.; Marais, R.; Dive, C.; Krebs, M. G.; Brognard, J.
10.1101/254342 — clinical trials — Posted on 2018-01-26
387 Integrating animal movement with habitat suitability for estimating dynamic landscape connectivity
van Toor, M. L.; Kranstauber, B.; Newman, S. H.; Prosser, D. J.; Takekawa, J. Y.; Technitis, G.; Weibel, R.; Wikelski, M.; Safi, K.
10.1101/224766 — ecology — Posted on 2018-01-26
395 Ventricular chamber-specific Pitx2 insufficiency leads to cardiac hypertrophy and arrhythmias
Chinchilla, A.; Esteban, F. J.; Lozano-Velasco, E.; Hernandez-Torres, F.; Dominguez, J. N.; Aranega, A. E.; Franco, D.
10.1101/253062 — developmental biology — Posted on 2018-01-26
396 Rapid Whole Genome Sequencing Decreases Morbidity and Healthcare Cost of Hospitalized Infants
Farnaes, L.; Hildreth, A.; Sweeney, N.; Clark, M.; Chowdhury, S.; Nahas, S.; Cakici, J.; Benson, W.; Kaplan, R.; Kronick, R.; Bainbridge, M.; Friedman, J.; Gold, J.; Ding, Y.; Veeraraghavan, N.; Dimmock, D.; kingsmore, S.; RCIGM Investigators,
10.1101/253534 — clinical trials — Posted on 2018-01-26
397 Signaling pathway screening platforms are an efficient approach toidentify therapeutic targets in precision-medicine oriented early phaseclinical trials
Torres Ayuso, ; Sahoo, S.; Galvin, M.; Leong, H. S.; Frese, K. K.; Cook, N.; Hughes, A.; Marais, R.; Dive, C.; Krebs, M. G.; Brognard, J.
10.1101/254342 — clinical trials — Posted on 2018-01-26
398 Fluidigm2PURC: automated processing and haplotype inference for double-barcoded PCR amplicons
Blischak, P. D.; Latvis, M.; Morales-Briones, D. F.; Johnson, J. C.; Di Stilio, V. S.; Wolfe, A. D.; Tank, D. C.
10.1101/242677 — bioinformatics — Posted on 2018-01-26
399 Inheritance of OCT4 predetermines fate choice in human embryonic stem cells
Wolff, S. C.; Dumitru, R.; Kedziora, K. M.; Dungee, C. D.; Zikry, T. M.; Haggerty, R. A.; Cheng, J.; Beltran, A. S.; Purvis, J. E.
10.1101/137299 — systems biology — Posted on 2018-01-26
400 Advanced Lesion Symptom Mapping Analyses And Implementation As BCBtoolkit
Foulon, C.; Cerliani, L.; Kinkingnehun, S.; Levy, R.; Rosso, C.; Urbanski, M.; Volle, E.; Thiebaut de Schotten, M.
10.1101/133314 — neuroscience — Posted on 2018-01-26
401 Reliability and correlation of fMRI, ECoG and EEG during natural stimulus processing
Haufe, S.; DeGuzman, P.; Henin, S.; Arcaro, M.; Honey, C. J.; Hasson, U.; Parra, L. C.
10.1101/207456 — neuroscience — Posted on 2018-01-26
403 Diversity and evolution of the emerging Pandoraviridae family
Legendre, M.; Fabre, E.; Poirot, O.; Jeudy, S.; Lartigue, A.; Alempic, J.-M.; Beucher, L.; Philippe, N.; Bertaux, L.; Labadie, K.; Coute, Y.; Abergel, C.; Claverie, J.-M.
10.1101/230904 — microbiology — Posted on 2018-01-26
404 Gut microbiota composition impacts host gene expression by changing chromatin accessibility
Richards, A.; Muehlbauer, A. L.; Alazizi, A.; Burns, M. B.; Gould, T. J.; Cascardo, C.; Pique-Regi, R.; Blekhman, R.; Luca, F.
10.1101/210294 — genomics — Posted on 2018-01-26
406 Detecting host-parasitoid interactions in an invasive Lepidopteran using nested tagging DNA-metabarcoding
Kitson, J. J. N.; Hahn, C.; Sands, R. J.; Straw, N. A.; Evans, D. M.; Lunt, D. H.
10.1101/035071 — ecology — Posted on 2018-01-26
410 The burden of dengue fever and chikungunya in southern coastal Ecuador: Epidemiology, clinical presentation, and phylogenetics from the first two years of a prospective study
Stewart-Ibarra, A. M.; Ryan, S. J.; Kenneson, A.; King, C. A.; Abbott, M.; Barbachano-Guerrero, A.; Beltran-Ayala, E.; Borbor-Cordova, M. J.; Cardenas, W.; Cueva, C.; Finkelstein, J. L.; Lupone, C. D.; Jarman, R. G.; Maljkovic Berry, I.; Mehta, S.; Polhemus, M.; Silva, M.; Endy, T. P.
10.1101/102004 — epidemiology — Posted on 2018-01-26
411 Gradual repression of selenoprotein W ensures physiological bone remodelling
Kim, H.; Lee, K.; Kim, J. M.; Kim, J.-R.; Lee, H.-W.; Chung, Y. W.; Shin, H.-I.; Park, E.-S.; Rho, J.; Lee, S. H.; Kim, N.; Lee, S. Y.; Choi, Y.; Jeong, D.
10.1101/254433 — physiology — Posted on 2018-01-26
412 A genetically encoded biosensor reveals location bias of opioid drug action
Stoeber, M.; Jullie, D.; Laeremans, T.; Steyaert, J.; Schiller, P. W.; Manglik, A.; von Zastrow, M.
10.1101/254490 — neuroscience — Posted on 2018-01-26
416 Multiple large-scale gene and genome duplications during the evolution of hexapods
Li, Z.; Tiley, G.; Galuska, S.; Reardon, C.; Kidder, T.; Rundell, R.; Barker, M. S.
10.1101/253609 — evolutionary biology — Posted on 2018-01-26
419 Dawn and photoperiod sensing by phytochrome A
Seaton, D.; Toledo-Ortiz, G.; Kubota, A.; Ganpudi, A.; Imaizumi, T.; Halliday, K.
10.1101/253989 — plant biology — Posted on 2018-01-25
423 Acute antidepressant effect of ayahuasca in juvenile non-human primate model of depression.
Santos da Silva, F.; Silva, E. A. d. S.; de Sousa Junior, G. M.; Maia-de-Oliveira, J. P.; Rachetti, V. d. P. S.; Barros de Araujo, D.; Cordeiro de Sousa, M. B.; Lobao Soares, B.; Leite Galvao-Coelho, N.
10.1101/254268 — neuroscience — Posted on 2018-01-25
425 Proteome-scale detection of drug-target interactions using correlations in transcriptomic perturbations
Pabon, N. A.; Xia, Y.; Estabrooks, S. K.; Ye, Z.; Herbrand, A. K.; Sub, E.; Biondi, R. M.; Assimon, V. A.; Gestwicki, J. E.; Brodsky, J. L.; Camacho, C. J.; Bar-Joseph, Z.
10.1101/254367 — genomics — Posted on 2018-01-25
432 Bayesian multi-scale modeling of macromolecular structures based on cryo-electron microscopy density maps
Hanot, S.; Bonomi, M.; Greenberg, C. H.; Sali, A.; Nilges, M.; Vendruscolo, M.; Pellarin, R.
10.1101/113951 — bioinformatics — Posted on 2018-01-25
434 Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1
Jabbari, N.; Glusman, G.; Joesch-Cohen, L. M.; Reddy, P. J.; Moritz, R. L.; Hood, L.; Lausted, C. G.
10.1101/200766 — genomics — Posted on 2018-01-25
436 Proteomic Profiling of Mammalian COPII Vesicles
Adolf, F.; Rhiel, M.; Hessling, B.; Hellwig, A.; Wieland, F. T.
10.1101/253294 — biochemistry — Posted on 2018-01-25
440 Exposure to the oral host niche yields rapid phenotypic and genotypic diversification in Candida albicans
Forche, A.; Cromie, G.; Gerstein, A. C.; Solis, N. V.; Pisithkul, T.; Srifa, W.; Jeffery, E.; Filler, S. G.; Dudley, A.; Berman, J.
10.1101/254201 — genetics — Posted on 2018-01-25
441 Systematic meta-analyses identify differentially expressed microRNAs in Parkinson’s disease
Schulz, J.; Takousis, P.; Wohlers, I.; Itua, I.; Dobricic, V.; Binder, H.; Middleton, L.; Ioannidis, J.; Perneczky, R.; Bertram, L.; Lill, C.
10.1101/253849 — genetics — Posted on 2018-01-25
442 Reduced-nutrient leachates in cash cover crop-soybean systems
Thom, M.; Forcella, F.; Eberle, C.; Matthees, H.; Weyers, S.; Gesch, R.; Ott, M.; Feyereisen, G.; Strock, J.; Wyse, D.
10.1101/254169 — ecology — Posted on 2018-01-25
445 Genetically encoded ratiometric indicators for potassium ion
Shen, Y.; Wu, S.-Y.; Rancic, V.; Qian, Y.; Miyashita, S.-I.; Ballanyi, K.; Campbell, R. E.; Dong, M.
10.1101/254383 — bioengineering — Posted on 2018-01-25
448 Idiosyncratic, retinotopic bias in face identification modulated by familiarity
Visconti di Oleggio Castello, M.; Taylor, M.; Cavanagh, P.; Gobbini, M. I.
10.1101/253468 — neuroscience — Posted on 2018-01-25
449 Conditional upregulation of KCC2 selectively enhances neuronal inhibition during seizures
Goulton, C. S.; Watanabe, M.; Cheung, D. L.; Wang, K. W.; Oba, T.; Khoshaba, A.; Lai, D.; Inada, H.; Eto, K.; Nakamura, K.; Power, J. M.; Lewis, T. M.; Housley, G. D.; Wake, H.; Nabekura, J.; Moorhouse, A. J.
10.1101/253831 — neuroscience — Posted on 2018-01-25
450 Fast Memory Integration Facilitated by Schema Consistency
Zhang, Q.; Popov, V.; Koch, G. E.; Calloway, R. C.; Coutanche, M. N.
10.1101/253393 — neuroscience — Posted on 2018-01-25
451 Toxoplasma gondii infection triggers chronic cachexia and sustained commensal dysbiosis in mice
Hatter, J. A.; Melchore, S. J.; Kouch, M.; Ng, K.; Bouley, D. W.; Boothroyd, J. C.; Ewald, S. E.
10.1101/247866 — microbiology — Posted on 2018-01-25
452 Assembly and validation of conserved long non-coding RNAs in the ruminant transcriptome
Bush, S. J.; Muriuki, C.; McCulloch, M. E. B.; Farquhar, I. L.; Clark, E. L.; Hume, D. A.
10.1101/253997 — genomics — Posted on 2018-01-25
458 Quantitative variation within a species for traits underpinning C4 photosynthesis
Reeves, G.; Singh, P.; Rossberg, T. A.; Sogbohossou, D.; Schranz, E.; Hibberd, J.
10.1101/253211 — plant biology — Posted on 2018-01-25
461 The yeast GRASP Grh1 displays a high polypeptide backbone mobility along with an amyloidogenic behavior
Fontana, N. A.; Fonseca-Maldonado, R.; Mendes, L. F. S.; Meleiro, L. P.; Costa-Filho, A. J.
10.1101/254144 — biophysics — Posted on 2018-01-25
463 A molecular framework for functional versatility of HECATE transcription factors
Gaillochet, C.; Jamge, S.; van der Wal, F.; Angenent, G.; Immink, R.; Lohmann, J. U.
10.1101/253815 — plant biology — Posted on 2018-01-25
470 Core Proteome and Architecture of COPI Vesicles
Rhiel, M.; Hessling, B.; Gao, Q.; Hellwig, A.; Adolf, F.; Wieland, F. T.
10.1101/254052 — biochemistry — Posted on 2018-01-25
472 Pain-related fear - From different fear constructs to dissociable neural sources
Meier, M. L.; Humphreys, B. K.; Vrana, A.; Seifritz, E.; Staempfli, P.; Schweinhardt, P.
10.1101/251751 — neuroscience — Posted on 2018-01-25
475 Using imaging photoplethysmography for heart rate estimation in non-human primates
Unakafov, A. M.; Moeller, S.; Kagan, I.; Gail, A.; Treue, S.; Wolf, F.
10.1101/252403 — bioengineering — Posted on 2018-01-25
478 Widely Used Commercial ELISA Does Not Detect Precursor ofHaptoglobin2, but Recognizes Properdin as a Potential Second Member of the Zonulin Family
Scheffler, L.; Crane, A.; Heyne, H. O.; Toenjes, A.; Schleinitz, D.; Ihling, C. H.; Stumvoll, M.; Freire, R.; Fiorentino, M.; Fasano, A.; Kovacs, P.; Heiker, J. T.
10.1101/157578 — molecular biology — Posted on 2018-01-25
479 Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation
Rodrigues-Alcazar, J. F.; Ataide, M. A.; Engels, G.; Schmitt-Mabmunyo, C.; Garbi, N.; Kastenmueller, W.; Latz, E.; Franklin, B. S.
10.1101/252957 — immunology — Posted on 2018-01-25
480 Combining global tree cover loss data with historical national forest-cover maps to look at six decades of deforestation and forest fragmentation in Madagascar
Vieilledent, G.; Grinand, C.; Rakotomalala, F. A.; Ranaivosoa, R.; Rakotoarijaona, J.-R.; Allnutt, T. F.; Achard, F.
10.1101/147827 — ecology — Posted on 2018-01-25
485 Developmental genetics of corolla tube formation: role of the tasiRNA-ARF pathway
Ding, B.; Xia, R.; Gurung, V.; Sagawa, J. M.; Stanley, L. E.; Strobel, M.; Lin, Q.; Diggle, P. K.; Meyers, B. C.; Yuan, Y.-W.
10.1101/253112 — plant biology — Posted on 2018-01-25
487 Neural engagement with online educational videos predicts learning performance for individual students
Cohen, S. S.; Madsen, J.; Touchan, G.; Robles, D.; Lima, S. F. A.; Henin, S.; Parra, L. C.
10.1101/253260 — neuroscience — Posted on 2018-01-25
489 A compact head-mounted endoscope for in vivo calcium imaging in freely-behaving mice
Jacob, A. D.; Ramsaran, A. I.; Mocle, A. J.; Tran, L. M.; Yan, C.; Frankland, P. W.; Josselyn, S. A.
10.1101/252205 — neuroscience — Posted on 2018-01-25
491 Sex-specific impact of prenatal androgens on intrinsic functional connectivity between social brain default mode subsystems
Lombardo, M. V.; Auyeung, B.; Pramparo, T.; Quartier, A.; Courraud, J.; Holt, R. J.; Waldman, J.; Ruigrok, A.; Mooney, N.; Lai, M.-C.; Kundu, P.; Bullmore, E. T.; Mandel, J.-L.; Piton, A.; Baron-Cohen, S.
10.1101/253310 — neuroscience — Posted on 2018-01-25
493 Neuromagnetic signatures of the spatiotemporal transformation for reaching
Blohm, G.; Alikhanian, H.; Gaetz, W.; Goltz, H. C.; DeSouza, J. F.; Cheyne, D. O.; Crawford, J. D.
10.1101/253328 — neuroscience — Posted on 2018-01-25
495 A perceptual decision making EEG/fMRI data set
Georgie, Y. K.; Porcaro, C.; Mayhew, S.; Bagshaw, A. P.; Ostwald, D.
10.1101/253047 — neuroscience — Posted on 2018-01-25
497 Metabarcoding analysis on European coastal samples reveals new molecular metazoan diversity
Lopez-Escardo, D.; Paps, J.; de Vargas, C.; Massana, R.; Ruiz-Trillo, I.; del Campo, J.
10.1101/253146 — microbiology — Posted on 2018-01-25
499 Multivariate analysis of the cotton seed ionome reveals a shared genetic architecture
Pauli, D.; Ziegler, G.; Ren, M.; Jenks, M. A.; Hunsaker, D. J.; Zhang, M.; Baxter, I.; Gore, M. A.
10.1101/213777 — genetics — Posted on 2018-01-25
502 Vascular plants are strong predictors of multi-taxon species richness
Brunbjerg, A. K.; Bruun, H. H.; Dalby, L.; Flojgaard, C.; Froslev, T.; Hoye, T. T.; Goldberg, I.; Laessoe, T.; Hansen, M. D. D.; Brondum, L.; Skipper, L.; Fog, K.; Ejrnaes, R.
10.1101/252999 — ecology — Posted on 2018-01-25
503 In Vivo Measurements of the Frequency-Dependent Impedance of the Spinal Cord
Utz, M.; Miller, J. W.; Reddy, C. G.; Wilson, S.; Abode-Iyamah, k. O.; Fredericks, D. C.; Gillies, G. T.; Howard, M. A.
10.1101/252965 — biophysics — Posted on 2018-01-25
504 qFit-ligand reveals widespread conformational heterogeneity of drug-like molecules in X-ray electron density maps
van Zundert, G. C.; Hudson, B. M.; Keedy, D. A.; Fonseca, R.; Heliou, A.; Suresh, P.; Borrelli, K.; Day, T.; Fraser, J. S.; van den Bedem, H.
10.1101/253419 — biophysics — Posted on 2018-01-25
505 WEADE: a workflow for enrichment analysis and data exploration
Trost, N.; Rempel, E.; Ermakova, O.; Tamirisa, S.; Parcalabescu, L.; Boutros, M.; Lohmann, J. U.; Lohmann, I.
10.1101/252924 — bioinformatics — Posted on 2018-01-25
506 A structural equation model for imaging genetics using spatial transcriptomics
Huisman, S. M. H.; Mahfouz, A.; Batmanghelich, N. K.; Lelieveldt, B. P. F.; Reinders, M. J. T.
10.1101/253443 — bioinformatics — Posted on 2018-01-25
510 Three-dimensional human axon tracts derived from cerebral organoids
Cullen, D. K.; Struzyna, L. A.; Jgamadze, D.; Gordian-Velez, W. J.; Lim, J.; Wofford, K. L.; Browne, K. D.; Chen, H. I.
10.1101/253369 — bioengineering — Posted on 2018-01-25
511 Dynamic combination of sensory and reward information under time pressure
Farashahi, S.; Ting, C.-C.; Kao, C.-H.; Wu, S.-W.; Soltani, A.
10.1101/253641 — neuroscience — Posted on 2018-01-25
512 Valproic acid attenuates hyperglycemia-induced complement and coagulation cascade gene expression
Felisbino, M. B.; Ziemann, M.; Khurana, I.; de Oliveira, C. B. M.; Mello, M. L. S.; El-Osta, A.
10.1101/253591 — molecular biology — Posted on 2018-01-25
514 A MinION-based pipeline for fast and cost-effective DNA barcoding
Srivathsan, A.; Baloglu, B.; Wang, W.; Tan, W. X.; Bertrand, D.; Ng, A. H. Q.; Boey, E. J. H.; Koh, J. J. Y.; Nagarajan, N.; Meier, R.
10.1101/253625 — bioinformatics — Posted on 2018-01-25
515 Attention periodically samples competing stimuli during binocular rivalry
Davidson, M. J.; Alais, D.; van Boxtel, J. J. A.; Tsuchiya, N.
10.1101/253740 — neuroscience — Posted on 2018-01-25
516 Multiplex Chromatin Interaction Analysis with Single-Molecule Precision
Zheng, M.; Tian, S. Z.; Maurya, R.; Lee, B.; Kim, M.; Capurso, D.; Piecuch, E.; Gong, L.; Zhu, J. J.; Wong, C. H.; Ngan, C. Y.; Wang, P.; Ruan, X.; Wei, C.-L.; Ruan, Y.
10.1101/252049 — genomics — Posted on 2018-01-25
520 Comparing complex variants in family trios
Toptas, B. C.; Rakocevic, G.; Komar, P.; Kural, D.
10.1101/253492 — bioinformatics — Posted on 2018-01-24
521 Behavioral and neural evidence of the rewarding value of exercise behaviors: A systematic review
Cheval, B.; Radel, R.; Neva, J. L.; Boyd, L. A.; Swinnen, S. P.; Sander, D.; Boisgontier, M. P.
10.1101/211425 — neuroscience — Posted on 2018-01-24
523 E. coli translation strategies differ across nutrient conditions
Li, S. H.-J.; Li, Z.; Park, J. O.; King, C. G.; Rabinowitz, J. D.; Wingreen, N. S.; Gitai, Z.
10.1101/224204 — microbiology — Posted on 2018-01-24
524 DNA methylation regulates transcriptional homeostasis of algal endosymbiosis in the coral model Aiptasia
Li, Y.; Liew, Y. J.; Cui, G.; Cziesielski, M. J.; Zahran, N.; Michell, C. T.; Voolstra, C. R.; Aranda Lastra, M.
10.1101/213066 — ecology — Posted on 2018-01-24
527 Cost evaluation during decision making in patients at early stages of psychosis
Ermakova, A. O.; Gileadi, N.; Knolle, F.; Justicia Diaz, A.; Anderson, R.; Fletcher, P. C.; Moutoussis, M.; Murray, G.
10.1101/225920 — neuroscience — Posted on 2018-01-24
528 Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four dimensional imaging
Politi, A. Z.; Cai, Y.; Walther, N.; Hossain, M. J.; Koch, B.; Wachsmuth, M.; Ellenberg, J.
10.1101/188862 — molecular biology — Posted on 2018-01-24
529 Generation and validation of homozygous fluorescent knock-in cells using genome editing
Koch, B.; Nijmeijer, B.; Kueblbeck, M.; Cai, Y.; Walther, N.; Ellenberg, J.
10.1101/188847 — molecular biology — Posted on 2018-01-24
530 Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation
Rodrigues-Alcazar, J. F.; Ataide, M. A.; Engels, G.; Schmitt-Mabmunyo, C.; Garbi, N.; Kastenmueller, W.; Latz, E.; Franklin, B. S.
10.1101/252957 — immunology — Posted on 2018-01-24
532 Reliability of Whole-Exome Sequencing for Assessing Intratumor Genetic Heterogeneity
Shi, W.; Ng, C. K. Y.; Lim, R. S.; Jiang, T.; Kumar, S.; Li, X.; Wali, V. B.; Piscuoglio, S.; Gerstein, M. B.; Chagpar, A. B.; Weigelt, B.; Pusztai, L.; Reis-Filho, J. S.; Hatzis, C.
10.1101/253195 — genomics — Posted on 2018-01-24
533 Genomewide association study identifies 30 loci associated with bipolar disorder
Stahl, E.; Breen, G.; Forstner, A.; McQuillin, A.; Ripke, S.; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Cichon, S.; Scott, L.; Ophoff, R.; Andreassen, O. A.; Kelsoe, J.; Sklar, P.
10.1101/173062 — genetics — Posted on 2018-01-24
537 The Specificity of IQGAP1 Toward the PI3K-Akt Pathway is Dependent on the IQ3 motif
Chen, M.; Wen, T.; Choi, S.; Thapa, N.; Jung, O.; Lambert, P.; Rapraeger, A. C.; Anderson, R. A.
10.1101/250936 — cell biology — Posted on 2018-01-24
538 Correlative live and super-resolution imaging reveals the dynamic structure of replication domains
Xiang, W.; Roberti, M. J.; Heriche, J.-K.; Huet, S.; Alexander, S.; Ellenberg, J.
10.1101/189373 — cell biology — Posted on 2018-01-24
539 Role of IQGAP1 in Head and Neck Carcinogenesis
Wei, T.; Choi, S.; Buehler, D.; Rapraeger, A.; Anderson, R.; Lambert, P.
10.1101/253484 — cancer biology — Posted on 2018-01-24
542 Structure-guided design of a cell penetrating peptide preventing cAMP modulation of HCN channels
Moroni, A.; Saponaro, A.; Cantini, F.; Porro, A.; Bucchi, A.; DiFrancesco, D.; Maione, V.; Donadoni, C.; Introini, B.; Mesirca, P.; Mangoni, M. E.; Thiel, G.; Banci, L.; Santoro, B.
10.1101/253096 — physiology — Posted on 2018-01-24
543 Gene Expression-Based Drug Repurposing to Target Ageing
Donertas, H. M.; Fuentealba Valenzuela, M.; Partridge, L.; Thornton, J.
10.1101/253344 — systems biology — Posted on 2018-01-24
546 SlARF10, an auxin response factor, is required for chlorophyll and sugar accumulation during tomato fruit development
Mei, L.; Yuan, Y.; Wu, M.; Gong, Z.; Zhang, Q.; Yang, F.; Zhang, Q.; Luo, Y.; Xu, X.; Zhang, W.; Miao, M.; Li, Z.; Deng, W.
10.1101/253237 — plant biology — Posted on 2018-01-24
553 The Streptococcus pneumoniae Competence-Induced BriC Peptide Promotes Nasopharyngeal Colonization and Impacts Biofilm Development
Aggarwal, S. D.; Eutsey, R.; West-Roberts, J.; Domenech, A.; Xu, W.; Abdullah, I. T.; Mitchell, A. P.; Veening, J.-W.; Yesilkaya, H.; Hiller, N. L.
10.1101/245902 — microbiology — Posted on 2018-01-24
554 Cell adhesion and fluid flow jointly initiate genotype spatial distribution in biofilms
Martinez-Garcia, R.; Nadell, C. D.; Hartmann, R.; Drescher, K.; Bonachela, J. A.
10.1101/243055 — microbiology — Posted on 2018-01-24
557 Whole genome sequencing for predicting Mycobacterium abscessus drug susceptibility
Lipworth, S. I. W.; Hough, N.; Leach, L.; Morgan, M.; Jeffrey, K.; Andersson, M.; Robinson, E.; Smith, G.; Crook, D.; Peto, T.; Walker, T.
10.1101/251918 — microbiology — Posted on 2018-01-24
558 Natural Secretory Immunoglobulins Enhance Norovirus Infection
Turula, H.; Bragazzi-Cunha, J.; Ramakrishnan, S.; Wilke, C.; Gonzalez-Hernandez, M.; Pry, A.; Fava, J.; Svoboda, S.; Shah, Y.; Corthesy, B.; Moore, B.; Wobus, C. E.
10.1101/253286 — microbiology — Posted on 2018-01-24
559 Endotoxin Tolerance Induced by Different TLR Ligands
Butcher, S. K.; O'Carroll, C.; Wells, C. A.; Carmody, R.
10.1101/250415 — immunology — Posted on 2018-01-24
560 Whole genome sequence of Mapuche-Huilliche Native Americans
Vidal, E. A.; Moyano, T. C.; Bustos, B. I.; Perez-Palma, E.; Moraga, C.; Montecinos, A.; Azocar, L.; Soto, D. C.; Riveras, E.; Vidal, M.; Di Genova, A.; Puschel, K.; Nuernberg, P.; Buch, S.; Hampe, J.; Allende, M. L.; Cambiazo, V.; Gonzalez, M.; Hodar, C.; Montecino, M.; Munoz-Espinoza, C.; Orellana, A.; Reyes-Jara, A.; Travisany, D.; Vizoso, P.; Moraga, M.; Eyheramendy, S.; Maass, A.; De Ferrari, G. V.; Miquel, J. F.; Gutierrez, R. A.
10.1101/252619 — genomics — Posted on 2018-01-24
563 Guiding Vaccine Efficacy Trial Design During Public Health Emergencies: An interactive web-based decision support tool
Bellan, S. E.; Eggo, R. M.; Gsell, P.-S.; Kucharski, A.; Dean, N.; Donohue, R.; Zook, M.; Odhiambo, F.; Longini, I.; Brisson, M.; Mahon, B.; Henao-Restrepo, A. M.
10.1101/252783 — epidemiology — Posted on 2018-01-24
565 Highly efficient chondrogenic differentiation of human iPSCs and purification via a reporter allele generated by CRISPR-Cas9 genome editing
Adkar, S. S.; Wu, C.-L.; Willard, V. P.; Dicks, A.; Ettyreddy, A.; Steward, N.; Bhutani, N.; Gersbach, C. A.; Guilak, F.
10.1101/252767 — cell biology — Posted on 2018-01-24
566 Detection of HPV E7 transcription at single-cell resolution in epidermis
Lukowski, S.; Tuong, K.; Noske, K.; Senabouth, A.; Nguyen, Q.; Soyer, P.; Frazer, I.; Powell, J.
10.1101/252858 — cell biology — Posted on 2018-01-24
567 Loss of E-cadherin enhances IGF1-IGF1R pathway activation and sensitizes breast cancers to anti-IGF1R inhibitors
Nagle, A.; Levine, K. M.; Tasdemir, N.; Scott, J. A.; Burlbaugh, K.; Kehm, J.; Katz, T. A.; Boone, D. N.; Jacobsen, B. M.; Atkinson, J. M.; Oesterreich, S.; Lee, A. V.
10.1101/253278 — cancer biology — Posted on 2018-01-24
568 Beyond synthetic lethality: multiple gene interaction types play a key functional role in cancer
Magen, A.; Das, A.; Sang Lee, J.; Sharmin, M.; Lugo, A.; Gutkind, S.; Ruppin, E.; Hannenhalli, S.
10.1101/253120 — cancer biology — Posted on 2018-01-24
569 MST1R/RON and EGFR in a complex with syndecans sustain carcinoma S-phase progression by preventing p38MAPK activation
Beauvais, D. M.; Short, K.; Stueven, N.; Nelson, S. E.; Lee, D.; Jung, O.; Anderson, R. A.; Lambert, P. F.; Rapraeger, A. C.
10.1101/252742 — cancer biology — Posted on 2018-01-24
570 The Folding Pathway of an Ig Domain is Conserved On and Off the Ribosome
Tian, P.; Steward, A.; Kudva, R.; Su, T.; Shilling, P. J.; Nickson, A. A.; Hollins, J. J.; Beckmann, R.; Von Heijne, G.; Best, R.; Clarke, J.
10.1101/253013 — biophysics — Posted on 2018-01-24
572 Detection of de novo copy number deletions from targeted sequencing of trios
Fu, J. M.; Leslie, E. J.; Scott, A. F.; Murray, J. C.; Marazita, M. L.; Beaty, T. H.; Scharpf, R. B.; Ruczinski, I.
10.1101/252833 — bioinformatics — Posted on 2018-01-24
575 Natural Gaze Data Driven Wheelchair
Raymond, L.-A.; Piccini, M.; Subramanian, M.; Orlov, P.; Faisal, A.
10.1101/252684 — bioengineering — Posted on 2018-01-24
576 Spatiotemporal mosaic patterning of pluripotent stem cells using CRISPR interference
Libby, A. R. G.; Joy, D. A.; So, P.-L.; Mandegar, M. A.; Muncie, J. M.; Weaver, V. M.; Conklin, B. R.; McDevitt, T. C.
10.1101/252189 — bioengineering — Posted on 2018-01-24
577 Structural variability of EspG chaperones from mycobacterial ESX-1, ESX-3 and ESX-5 type VII secretion systems
Tuukkanen, A. T.; Freire, D.; Chan, S.; Arbing, M. A.; Reed, R. W.; Evans, T. J.; Zenkeviciute, G.; Kim, J.; Kahng, S.; Sawaya, M. R.; Wilmanns, M.; Eisenberg, D.; Parret, A. H. A.; Korotkov, K. V.
10.1101/250803 — biochemistry — Posted on 2018-01-24
579 Coincident binding of synthetic and natural ligands to the nuclear receptor PPARγ
Shang, J.; Brust, R.; Mosure, S. A.; Bass, J.; Munoz-Tello, P.; Lin, H.; Hughes, T. S.; Tang, M.; Ge, Q.; Kamekencka, T. M.; Kojetin, D. J.
10.1101/252817 — biochemistry — Posted on 2018-01-24
580 Proteomic Profiling of Mammalian COPII Vesicles
Adolf, F.; Rhiel, M.; Hessling, B.; Hellwig, A.; Wieland, F. T. T.
10.1101/253294 — biochemistry — Posted on 2018-01-24
584 Measurement of the Persistence Length of Cytoskeletal Filaments using Curvature Distributions
Wisanpitayakorn, P.; Mickolajczyk, K. J.; Hancock, W. O.; Vidali, L.; Tuzel, E.
10.1101/252551 — biophysics — Posted on 2018-01-23
585 Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance.
Stein-O'Brien, G.; Kagohara, L. T.; Li, S.; Thakar, M.; Ranaweera, R.; Ozawa, H.; Cheng, H.; Considine, M.; Schmitz, S.; Favorov, A.; Danilova, L.; Califano, J. A.; Izumchenko, E.; Gaykalova, D. A.; Chung, C. H.; Fertig, E. J.
10.1101/136564 — systems biology — Posted on 2018-01-23
587 Unbiased construction of a temporally consistent morphological atlas of neonatal brain development
Schuh, A.; Makropoulos, A.; Robinson, E. C.; Cordero-Grande, L.; Hughes, E.; Hutter, J.; Price, A.; Murgasova, M.; Teixeira, R. P. A. G.; Tusor, N.; Steinweg, J. K.; Victor, S.; Rutherford, M. A.; Hajnal, J. V.; Edwards, A. D.; Rueckert, D.
10.1101/251512 — neuroscience — Posted on 2018-01-23
588 Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy
Weigert, M.; Schmidt, U.; Boothe, T.; Müller, A.; Dibrov, A.; Jain, A.; Wilhelm, B.; Schmidt, D.; Broaddus, C.; Culley, S.; Rocha-Martins, M.; Segovia-Miranda, F.; Norden, C.; Henriques, R.; Zerial, M.; Solimena, M.; Rink, J.; Tomancak, P.; Royer, L.; Jug, F.; Myers, E. W.
10.1101/236463 — bioinformatics — Posted on 2018-01-23
591 Dopamine and eye movement control in Parkinson’s disease: deficits in corollary discharge signals
Railo, H.; Olkoniemi, H.; Eeronheimo, E.; Paakkonen, O.; Joutsa, J.; Kaasinen, V.
10.1101/245381 — neuroscience — Posted on 2018-01-23
592 NRSF-mediated repression of neuronal genes in developing brain persists in the absence of NRSF-Sin3 interaction
Hall, A. M.; Short, A. K.; Singh-Taylor, A.; Daglian, J.; Mishina, T.; Schmidt, W. K.; Kouji, H.; Baram, T. Z.
10.1101/245993 — neuroscience — Posted on 2018-01-23
597 The fitness landscape of the codon space across environments
Fragata, I.; Matuszweski, S.; Schmitz, M. A.; Bataillon, T.; Jensen, J. D.; Bank, C.
10.1101/252395 — evolutionary biology — Posted on 2018-01-23
598 Evidence for subsoil specialization in arbuscular mycorrhizal fungi
Sosa-Hernandez, M. A.; Roy, J.; Hempel, S.; Rillig, M. C.
10.1101/252544 — ecology — Posted on 2018-01-23
599 Chiral cilia orientation in the left-right organizer
Rua Ferreira, R.; Pakula, G.; Vilfan, A.; Supatto, W.; Vermot, J.
10.1101/252502 — developmental biology — Posted on 2018-01-23
600 The Chlamydia type III effector TarP alters the dynamics and organization of host focal adhesions
Pedrosa, A. T.; Nogueira, A. T.; Thwaites, T. R.; Aaron, J.; Chew, T.-L.; Carabeo, R. A.
10.1101/250563 — cell biology — Posted on 2018-01-23
602 Microtubule acetylation is required for mechanosensation in Drosophila
Yan, C.; Wang, F.; Peng, Y.; Williams, C. R.; Jenkins, B.; Willdonger, J.; Tuthill, J. C.; Xiang, Y.; Rogers, S. L.; Parrish, J. Z.
10.1101/252601 — cell biology — Posted on 2018-01-23
603 Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations
Hauser, K.; Negron, C.; Albanese, S. K.; Ray, S.; Steinbrecher, T.; Abel, R.; Chodera, J. D.; Wang, L.
10.1101/239012 — cancer biology — Posted on 2018-01-23
604 Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins
Allen, R. M.; Zhao, S.; Ramirez-Solano, M. A.; Michell, D. L.; Wang, Y.; Shyr, Y.; Sethupathy, P.; Linton, M. F.; Graf, G. A.; Sheng, Q.; Vickers, K. C.
10.1101/246900 — bioinformatics — Posted on 2018-01-23
605 Modifiable risk factors moderate the relationship between amyloid and cognition in midlife
Clark, L. R.; Koscik, R. L.; Allison, S. L.; Berman, S. E.; Carlsson, C. M.; Norton, D. L.; Bendlin, B. B.; Asthana, S.; Betthauser, T. J.; Christian, B. T.; Johnson, S. C.
10.1101/229062 — neuroscience — Posted on 2018-01-23
606 Longitudinal standards for mid-life cognitive performance: Identifying abnormal within-person changes in the Wisconsin Registry for Alzheimer’s Prevention
Koscik, R. L.; Jonaitis, E. M.; Clark, L. R.; Mueller, K. D.; Allison, S. L.; Gleason, C. E.; Chappell, R. J.; Hermann, B. P.; Johnson, S. C.
10.1101/229146 — neuroscience — Posted on 2018-01-23
607 Characterizing the effects of sex, APOE ɛ4, and literacy on mid-life cognitive trajectories: Application of Information-Theoretic model-averaging and multi-model inference techniques to the Wisconsin Registry for Alzheimer’s Prevention Study
Koscik, R. L.; Norton, D. L.; Allison, S. L.; Jonaitis, E. M.; Clark, L. R.; Mueller, K. D.; Hermann, B. P.; Engelman, C. D.; Gleason, C. E.; Sager, M. A.; Chappell, R. J.; Johnson, S. C.
10.1101/229237 — neuroscience — Posted on 2018-01-23
609 Comparison of Small Gut and Whole Gut Microbiota of First-Degree Relatives with Adult Celiac Disease Patients and Controls
Shetty, S. A.; Bodkhe, R.; Dhotre, D. P.; Verma, A. K.; Bhatia, K.; Mishra, A.; Kaur, G.; Pande, P.; Bangarusamy, D. K.; Santosh, B. P.; Perumal, R. C.; Ahuja, V.; Shouche, Y. S.; Makharia, G. K.
10.1101/227272 — microbiology — Posted on 2018-01-23
610 Marine proteorhodopsins rival photosynthesis in solar energy capture
Gomez-Consarnau, L.; Levine, N. M.; Cutter, L. S.; Wang, D.; Seegers, B.; Aristegui, J.; Fuhrman, J. A.; Gasol, J. M.; Sanudo-Wilhelmy, S. A.
10.1101/231167 — ecology — Posted on 2018-01-23
611 Cardiac metabolic effects of KNa1.2 channel deletion, and evidence for its mitochondrial localization.
Smith, C. O.; Wang, Y. T.; Nadtochiy, S. M.; Miller, J. H.; Jonas, E. A.; Dirksen, R. T.; Nehrke, K.; Brookes, P. S.
10.1101/223321 — cell biology — Posted on 2018-01-23
612 Genome analysis and data sharing informs timing of molecular events in pancreatic neuroendocrine tumour
Quevedo, R.; Spreafico, A.; Bruce, J.; Danesh, A.; Giesler, A.; Hanna, Y.; Have, C.; Li, T.; Yang, S. Y. C.; Zhang, T.; Asa, S. L.; Haibe-Kains, B.; Kamel-Reid, S.; Krzyzanowska, M.; Smith, A.; Singh, S.; Siu, L. L.; Pugh, T. J.
10.1101/232850 — cancer biology — Posted on 2018-01-23
613 Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy
Weigert, M.; Schmidt, U.; Boothe, T.; Müller, A.; Dibrov, A.; Jain, A.; Wilhelm, B.; Schmidt, D.; Broaddus, C.; Culley, S.; Rocha-Martins, M.; Segovia-Miranda, F.; Norden, C.; Henriques, R.; Zerial, M.; Solimena, M.; Rink, J.; Tomancak, P.; Royer, L.; Jug, F.; Myers, E. W.
10.1101/236463 — bioinformatics — Posted on 2018-01-23
614 The importance of geometry in the corneal micropocket angiogenesis assay
Grogan, J. A.; Connor, A. J.; Pitt-Francis, J. M.; Maini, P. K.; Byrne, H. M.
10.1101/193433 — physiology — Posted on 2018-01-23
615 Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid
Clark, L.; Berman, S.; Norton, D.; Koscik, R.; Jonaitis, E.; Blennow, K.; Bendlin, B.; Asthana, S.; Johnson, S.; Zetterberg, H.; Carlsson, C.
10.1101/220756 — neuroscience — Posted on 2018-01-23
616 Neural circuits for long-range color filling-in
Gerardin, P.; Abbatecola, C.; Devinck, F.; Kennedy, H.; Dojat, M.; Knoblauch, K.
10.1101/223156 — neuroscience — Posted on 2018-01-23
620 Enhancing resolution of natural methylome reprogramming behavior in plants
Sanchez, R.; Yang, X.; Kundariya, H.; Barreras, J. R.; Wamboldt, Y.; Mackenzie, S.
10.1101/252106 — genomics — Posted on 2018-01-23
621 Ethylene mitigates waterlogging stress by regulating glutathione biosynthesis-related transcripts in soybeans
Kim, Y.; Seo, C.-W.; Khan, A. L.; Mun, B.-G.; Shahzad, R.; Ko, J.-W.; Yun, B.-W.; Lee, I.-J.
10.1101/252312 — plant biology — Posted on 2018-01-23
622 Lrfn2-mutant mice display suppressed synaptic plasticity and inhibitory synapse development and abnormal social communication and startle response
Li, Y.; Kim, R.; Cho, Y. S.; Kim, D.; Kim, K.; Roh, J. D.; Park, H.; Yang, E.; Kim, S.-J.; Ko, J.; Kim, H.; Bae, Y.-C.; Kim, E.
10.1101/252429 — neuroscience — Posted on 2018-01-23
624 Altered Developmental Trajectories in Intrinsic Function between Default, Salience, and Executive Networks in High-Functioning Autism
Yang, L.; Chen, X.; Li, X.; Shen, Y.-Q.; Wang, H.; Liu, J.-R.; Mei, T.; Ji, Z.-Z.; Guo, Y.-Q.; Wang, F.-F.; Xu, L.-Z.; Tang, X.-Z.; Ma, Z.-H.; Wang, L.-Q.; Liu, J.; Cao, Q.-J.; Yan, C.-G.
10.1101/252320 — neuroscience — Posted on 2018-01-23
625 Cellular tolerance at the μ-opioid receptor is phosphorylation dependent
Williams, J. T.; Arttamangkul, S.; Heinze, D. A.; Bunzow, J. R.; Song, X.
10.1101/252387 — neuroscience — Posted on 2018-01-23
628 Latin Americans show wide-spread Converso ancestry and the imprint of local Native ancestry on physical appearance
Chacon-Duque, J. C.; Adhikari, K.; Fuentes-Guajardo, M.; Mendoza-Revilla, J.; Acuna-Alonzo, V.; Barquera Lozano, R.; Quinto-Sanchez, M.; Gomez-Valdes, J.; Everardo Martinez, P.; Villamil-Ramirez, H.; Hunemeier, T.; Ramallo, V.; Silva de Cerqueira, C. C.; Hurtado, M.; Villegas, V.; Granja, V.; Villena, M.; Vasquez, R.; Llop, E.; Sandoval, J. R.; Salazar-Granara, A. A.; Parolin, M.-L.; Sandoval, K.; Penaloza-Espinosa, R. I.; Rangel-Villalobos, H.; Winkler, C.; Klitz, W.; Bravi, C.; Molina, J.; Corach, D.; Barrantes, R.; Gomes, V.; Resende, C.; Gusmao, L.; Amorim, A.; Xue, Y.; Dugoujon, J.-M.; Mo
10.1101/252155 — genetics — Posted on 2018-01-23
630 A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research
De Jager, P.; Ma, Y.; McCabe, C.; Xu, J.; Vardarajan, B. N.; Felsky, D.; Klein, H.-U.; White, C. C.; Peters, M. A.; Lodgson, B.; Nejad, P.; Tang, A.; Mangravite, L. M.; Yu, L.; Gaiteri, C.; Mostafavi, S.; Schneider, J. A.; Bennett, D. A.
10.1101/251967 — cell biology — Posted on 2018-01-23
633 Feedback control of neurogenesis by tissue packing
Hiscock, T. W.; Miesfeld, J. B.; Mosaliganti, K. R.; Link, B. A.; Megason, S. G.
10.1101/252445 — developmental biology — Posted on 2018-01-23
635 Harmonizing semantic annotations for computational models in biology
Neal, M. L.; König, M.; Nickerson, D.; Mısırlı, G.; Kalbasi, R.; Dräger, A.; Atalag, K.; Chelliah, V.; Cooling, M.; Cook, D. L.; Crook, S.; de Alba, M.; Friedman, S. H.; Garny, A.; Gennari, J. H.; Gleeson, P.; Golebiewski, M.; Hucka, M.; Juty, N.; Le Novere, N.; Myers, C.; Olivier, B. G.; Sauro, H. M.; Scharm, M.; Snoep, J. L.; Toure, V.; Wipat, A.; Wolkenhauer, O.; Waltemath, D.
10.1101/246470 — scientific communication and education — Posted on 2018-01-23
639 Rhythmic neural spiking and attentional samplingarising from cortical receptive field interactions
Kienitz, R.; Schmiedt, J. T.; Shapcott, K. A.; Kouroupaki, K.; Saunders, R.; Schmid, M. C.
10.1101/252130 — neuroscience — Posted on 2018-01-23
641 Polygenic scores without external summary statistics
Mak, T.; Porsch, R. M.; Choi, S. W.; Sham, P. C.
10.1101/252270 — genomics — Posted on 2018-01-23
642 An atlas of silencer elements for the human and mouse genomes
Doni Jayavelu, N.; Jajodia, A.; Mishra, A.; Hawkins, R. D.
10.1101/252304 — genomics — Posted on 2018-01-23
644 Selection-free, high frequency genome editing by homologous recombination of human pluripotent stem cells using Cas9 RNP and AAV6
Martin, R.; Ikeda, K.; Uchida, N.; Cromer, M. K.; Nishimura, T.; Dever, D. P.; Camarena, J.; Bak, R.; Lausten, A.; Jakobsen, M. R.; Wiebking, V.; Sebastiano, V.; Nakauchi, H.; Porteus, M. H.
10.1101/252163 — bioengineering — Posted on 2018-01-23
647 phospho-ERK is a response biomarker to a combination of sorafenib and MEK inhibition in liver cancer
Bernards, R. R.; Wang, C.; Jin, H.; Gao, D.; Evers, B.; Jin, G.; Xue, Z.; Wang, L.; Beijersbergen, R.; Qin, W.-X.
10.1101/252452 — cancer biology — Posted on 2018-01-23
648 High precision automated detection of labelednuclei in terabyte-scale whole-brain volumetricimage data of mouse
Pahariya, G.; Das, S.; Jayakumar, J.; Bannerjee, S.; Vangala, V.; Ram, K.; Mitra, P. P.
10.1101/252247 — neuroscience — Posted on 2018-01-23
649 2-APB arrests human keratinocyte proliferation and inhibits cutaneous squamous cell carcinoma in vitro
Nelson, A. M.; Moayedi, Y.; Greenberg, S. A.; Ruiz, M. E.; Jensen, U. B.; Owens, D. M.; Lumpkin, E. A.
10.1101/249821 — cell biology — Posted on 2018-01-23
650 Spatiotemporal mosaic patterning of pluripotent stem cells using CRISPR interference
Libby, A. R. G.; Joy, D. A.; Po, P.-L.; Mandegar, M. A.; Muncie, J. M.; Weaver, V. M.; Conklin, B. R.; McDevitt, T. C.
10.1101/252189 — bioengineering — Posted on 2018-01-23
651 Compressed timeline of recent experience in monkey lPFC
Tiganj, Z.; Cromer, J. A.; Roy, J. E.; Miller, E. K.; Howard, M. W.
10.1101/126219 — neuroscience — Posted on 2018-01-22
655 High-resolution wide-field human brain tumor margin detection and in vivo murine neuroimaging
Yecies, D.; Liba, O.; SoRelle, E.; Dutta, R.; Yuan, E.; Vogel, H.; Grant, G.; de la Zerda, A.
10.1101/252080 — bioengineering — Posted on 2018-01-22
656 Quantitative Assessment of Protein Activity in Orphan Tissues and Single Cells Using the metaVIPER Algorithm
Ding, H.; Douglass, E. F.; Sonabend, A. M.; Mela, A.; Bose, S.; Gonzalez, C.; Canoll, P. D.; Sims, P. A.; Alvarez, M. J.; Califano, A.
10.1101/252072 — systems biology — Posted on 2018-01-22
657 Fine-tuning of ABA responses by the protein kinase WNK8
Waadt, R.; Hashimoto, K.; Jawurek, E.; Krebs, M.; Scholz, M.; Hong-Hermesdorf, A.; Li, Y.; Hippler, M.; Grill, E.; Kudla, J.; Schumacher, K.
10.1101/251975 — plant biology — Posted on 2018-01-22
659 From preliminary to definitive plans: two classes of neurons in frontal eye field
Glaser, J. I.; Wood, D. K.; Lawlor, P. N.; Segraves, M. A.; Kording, K. P.
10.1101/251835 — neuroscience — Posted on 2018-01-22
661 A constraint-based model reveals hysteresis in island biogeography
Burger, J. R.; Anderson, R. P.; Balk, M. A.; Fristoe, T. S.
10.1101/251926 — ecology — Posted on 2018-01-22
663 Molecular control of gene expression by Brucella BaaR, an IclR-family repressor
Herrou, J.; Czyc, D. M.; Fiebig, A.; Willett, J. W.; Kim, Y.; Wu, R.; Babnigg, G.; Crosson, S.
10.1101/251942 — biochemistry — Posted on 2018-01-22
664 Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain
Bellessort, B.; Bachelot, A.; Grouthier, V.; De Lombares, C.; Narboux-Neme, N.; Garagnani, P.; Pirazzini, C.; Astigiano, S.; Mastracci, L.; Fontaine, A.; Alfama, G.; Duvernois-Berthet, E.; Levi, G.
10.1101/251397 — pharmacology and toxicology — Posted on 2018-01-22
666 Effect of head volume conduction on directed connectivity estimated between reconstructed EEG sources
Anzolin, A.; Presti, P.; Van de Steen, F.; Astolfi, L.; Haufe, S.; Marinazzo, D.
10.1101/251223 — neuroscience — Posted on 2018-01-22
668 Loss of PRMT5 promotes PDGFRα degradation during oligodendrocyte differentiation and myelination
Calabretta, S.; Vogel, G.; Yu, Z.; Choquet, K.; Darbelli, L.; Nicholson, T. B.; Kleinman, C. L.; Richard, S.
10.1101/252056 — molecular biology — Posted on 2018-01-22
670 Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1
Jabbari, N.; Glusman, G.; Joesch-Cohen, L. M.; Reddy, P. J.; Moritz, R. L.; Hood, L.; Lausted, C. G.
10.1101/200766 — genomics — Posted on 2018-01-22
671 A non-canonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells
Srinivasan, S.; Burckhardt, C. J.; Bhave, M.; Chen, Z.; Chen, P.-H.; Wang, X.; Danuser, G.; Schmid, S. L.
10.1101/251983 — cell biology — Posted on 2018-01-22
672 The actin cytoskeleton of the mouse sperm flagellum is organized in a helical structure
Gervasi, M. G.; Xu, X.; Carbajal-Gonzalez, B.; Buffone, M. G.; Visconti, P.; Krapf, D.
10.1101/252064 — cell biology — Posted on 2018-01-22
674 Comprehensive, integrated and phased whole-genome analysis of the primary ENCODE cell line K562
Zhou, B.; Ho, S. S.; Zhu, X.; Zhang, X.; Spies, N.; Byeon, S.; Arthur, J. G.; Pattni, R.; Ben-Efraim, N.; Haney, M. S.; Haraksingh, R. R.; Song, G.; Perrin, D.; Wong, W. H.; Abyzov, A.; Urban, A. E.
10.1101/192344 — genomics — Posted on 2018-01-22
675 Large differences in small RNA composition between human biofluids
Godoy, P. M.; Bhakta, N. R.; Barczak, A. J.; Cakmak, H.; Fisher, S.; Mackenzie, T. C.; Patel, T.; Price, R. W.; Smith, J. F.; Woodruff, P. G.; Erle, D. J.
10.1101/251496 — genomics — Posted on 2018-01-22
677 Higher transcriptome stability during aging in long-lived giant mole-rats compared to short-lived rats
Sahm, A.; Bens, M.; Henning, Y.; Vole, C.; Groth, M.; Schwab, M.; Platzer, M.; Szafranski, K.; Dammann, P.
10.1101/251777 — systems biology — Posted on 2018-01-22
680 Network-based asymmetry of the human auditory system
Misic, B.; Betzel, R. F.; Griffa, A.; de Reus, M. A.; He, Y.; Zuo, X.-N.; van den Heuvel, M. P.; Hagmann, P.; Sporns, O.; Zatorre, R. J.
10.1101/251827 — neuroscience — Posted on 2018-01-22
681 nNOS-expressing neurons in the ventral tegmental area and substantia nigra pars compacta
Paul, E.; Kalk, E.; Tossell, K.; Irvine, E.; Withers, D.; Leiper, J.; Ungless, M. A.
10.1101/251843 — neuroscience — Posted on 2018-01-22
682 Interaction of septin 7 and DOCK8 in equine lymphocytes reveals novel insights into signaling pathways associated with autoimmunity
Schauer, M.; Kleinwort, K. J. H.; Degroote, R. L.; Wiedemann, C.; Kremmer, E.; Hauck, S. M.; Deeg, C. A.
10.1101/251819 — immunology — Posted on 2018-01-22
683 Rapid and dynamic alternative splicing impacts the Arabidopsis cold response transcriptome
Calixto, C. P. G.; Guo, W.; James, A. B.; Tzioutziou, N. A.; Entizne, J. C.; Panter, P. E.; Knight, H.; Nimmo, H. G.; Zhang, R.; Brown, J.
10.1101/251876 — genomics — Posted on 2018-01-22
684 Modeling Avian Full Annual Cycle Distribution and Population Trends with Citizen Science Data
Fink, D.; Auer, T.; Ruiz-Gutierrez, V.; Hochachka, W. M.; Johnston, A.; La Sorte, F. A.; Kelling, S.
10.1101/251868 — ecology — Posted on 2018-01-22
697 Severely impaired bone material quality in Chihuahua zebrafish resembles classical dominant human osteogenesis imperfecta
Fiedler, I. A. K.; Schmidt, F. N.; Plumeyer, C.; Milovanovic, P.; Gioia, R.; Tonelli, F.; Forlino, A.; Busse, B.
10.1101/251652 — pathology — Posted on 2018-01-22
699 A probabilistic atlas of the human pyramidal tract in 410 healthy participants
Chenot, Q.; Tzourio-Mazoyer, N.; Rheault, F.; Descoteaux, M.; Crivello, F.; Zago, L.; Mellet, E.; Jobard, G.; Joliot, M.; Mazoyer, B.; Petit, L.
10.1101/251108 — neuroscience — Posted on 2018-01-22
701 Unbiased construction of a temporally consistent morphological atlas of neonatal brain development
Schuh, A.; Makropoulos, A.; Robinson, E. C.; Cordero-Grande, L.; Hughes, E.; Hutter, J.; Price, A.; Murgasova, M.; Teixeira, R. P. A. G.; Tusa, N.; Steinweg, J.; Victor, S.; Rutherford, M. A.; Hajnal, J. V.; Edwards, D. A.; Rueckert, D.
10.1101/251512 — neuroscience — Posted on 2018-01-22
703 Linear-Nonlinear-Time-Warp-Poisson models of neural activity
Lawlor, P. N.; Perich, M. G.; Miller, L. E.; Kording, K. P.
10.1101/194498 — neuroscience — Posted on 2018-01-22
704 Effect of head volume conduction on directed connectivity estimated between reconstructed EEG sources
Anzolin, A.; Presti, P.; Van de Steen, F.; Astolfi, L.; Haufe, S.; Marinazzo, D.
10.1101/251223 — neuroscience — Posted on 2018-01-22
706 The Neural Architecture of Executive Functions Is Established by Middle Childhood
Engelhardt, L. E.; Harden, K. P.; Tucker-Drob, E. M.; Church, J. A.
10.1101/251447 — neuroscience — Posted on 2018-01-22
708 E. coli translation strategies differ across nutrient conditions
Li, S. H.-J.; Li, Z.; Park, J. O.; King, C. G.; Rabinowitz, J. D.; Wingreen, N. S.; Gitai, Z.
10.1101/224204 — microbiology — Posted on 2018-01-22
709 A genomic island of Streptomyces coelicolor with the self-contained regulon of an ECF sigma factor
Kao, C. M.; Karoonuthaisiri, N.; Weaver, D.; Vroom, J. A.; Gai, S. A.; Ho, M.-L.; Patel, K. G.
10.1101/247056 — microbiology — Posted on 2018-01-22
710 A hypermorphic Nfkbid allele represents an Idd7 locus gene contributing to impaired thymic deletion of autoreactive diabetogenic CD8+ T-cells in NOD mice.
Presa, M.; Racine, J. J.; Lamont, D.; Dwyer, J.; Ratiu, J.; Sarsani, V. K.; Chen, Y.-G.; Geurts, A.; Schmitz, I.; Stearns, T.; Allocco, J.; Chapman, H. D.; Serreze, D. V.
10.1101/249094 — immunology — Posted on 2018-01-22
712 Large differences in small RNA composition between human biofluids
Godoy, P. M.; Bhakta, N. R.; Barczak, A. J.; Cakmak, H.; Fisher, S.; Mackenzie, T. C.; Patel, T.; Price, R. W.; Smith, J. F.; Woodruff, P. G.; Erle, D. J.
10.1101/251496 — genomics — Posted on 2018-01-22
713 Including phenotypic causal networks in genome-wide association studies using mixed effects structural equation models
Momen, M.; Mehrgardi, A. A.; Roudbar, M. A.; Kranis, A.; Pinto, R. M.; Valente, B. D.; Morota, G.; Rosa, G. J.; Gianola, D.
10.1101/251421 — genetics — Posted on 2018-01-22
714 Timing malaria transmission with mosquito fluctuations
Pigeault, R.; Caudron, Q.; Nicot, A.; Rivero, A.; Gandon, S.
10.1101/251728 — evolutionary biology — Posted on 2018-01-22
719 New mining concessions will severely decrease biodiversity and ecosystem services in Ecuador
Roy, B. A.; Zorrilla, M.; Endara, L.; Thomas, D. C.; Vandegrift, R.; Rubenstein, J. M.; Policha, T.; Rios-Touma, B.
10.1101/251538 — ecology — Posted on 2018-01-22
721 The universal mechanism of intermediate filament transport
Robert, A.; Tian, P.; Adam, S. A.; Goldman, R. D.; Gelfand, V. I.
10.1101/251405 — cell biology — Posted on 2018-01-22
723 Autometa: Automated extraction of microbial genomes from individual shotgun metagenomes
Miller, I. J.; Rees, E. R.; Ross, J.; Miller, I.; Baxa, J.; Lopera, J.; Kerby, R. L.; Rey, F. E.; Kwan, J. C.
10.1101/251462 — bioinformatics — Posted on 2018-01-22
727 Imaging neural activity in the ventral nerve cord of behaving adult Drosophila
Chen, C.-L.; Hermans, L.; Viswanathan, M. C.; Fortun, D.; Unser, M.; Cammarato, A.; Dickinson, M. H.; Ramdya, P.
10.1101/250118 — neuroscience — Posted on 2018-01-22
728 Ciliary and rhabdomeric photoreceptor-cell circuits form a spectral depth gauge in marine zooplankton
Veraszto, C.; Guhmann, M.; Jia, H.; Rajan, V. B. V.; Bezares-Calderon, L. A.; Lopez, C. P.; Randel, N.; Shahidi, R.; Michiels, N. K.; Yokoyama, S.; Tessmar-Raible, K.; Jekely, G.
10.1101/251686 — neuroscience — Posted on 2018-01-22
731 How Do Telomeres Block Checkpoint Activation?
Runge, K.; Audry, J.; Wang, J.; Eisenstatt, J.; Sanders, S. L.; Berkner, K. L.
10.1101/251389 — molecular biology — Posted on 2018-01-22
737 Sex Differences In The Adult Human Brain: Evidence From 5,216 UK Biobank Participants
Ritchie, S. J.; Cox, S. R.; Shen, X.; Lombardo, M. V.; Reus, L. M.; Alloza, C.; Harris, M. A.; Alderson, H.; Hunter, S.; Neilson, E.; Liewald, D. C.; Auyeung, B.; Whalley, H. C.; Lawrie, S. M.; Gale, C. R.; Bastin, M. E.; McIntosh, A. M.; Deary, I. J.
10.1101/123729 — neuroscience — Posted on 2018-01-22
738 Replication timing shapes the cancer epigenome and the nature of chromosomal rearrangements
Du, Q.; Bert, S. A.; Armstrong, N. J.; Caldon, C. E.; Song, J. Z.; Nair, S. S.; Gould, C. M.; Luu, P. L.; Khoury, A.; Qu, W.; Zotenko, E.; Stirzaker, C.; Clark, S.
10.1101/251280 — genomics — Posted on 2018-01-22
739 HOTAIR ancient sequence suggests regulatory roles both in cis and trans
Nepal, C.; Hadzheiv, Y.; Pundhir, S.; Mydel, P.; Lenhard, B.; Mueller, F.; Andersen, J. B.
10.1101/250621 — genomics — Posted on 2018-01-22
742 Functional repurposing of regulatory element activity during mammalian evolution
Carelli, F. N.; Liechti, A.; Halbert, J.; Warnefors, M.; Kaessmann, H.
10.1101/251371 — genomics — Posted on 2018-01-22
745 Global determinants of navigation ability
Coutrot, A.; Silva, R.; Manley, E.; de Cothi, W.; Sami, S.; Bohbot, V.; Wiener, J.; Hölscher, C.; Dalton, R. C.; Hornberger, M.; Spiers, H.
10.1101/188870 — neuroscience — Posted on 2018-01-21
746 Generic assembly patterns in complex ecological communities
Barbier, M.; Arnoldi, J.-F.; Bunin, G.; Loreau, M.
10.1101/145862 — ecology — Posted on 2018-01-21
748 Parallel holographic illumination enables sub-millisecond two-photon optogenetic activation in mouse visual cortex in vivo
Chen, I.-W.; Ronzitti, E.; Lee, B. R.; Daigle, T. L.; Zeng, H.; Papagiakoumou, E.; Emiliani, V.
10.1101/250795 — neuroscience — Posted on 2018-01-21
749 E. coli translation strategies differ across nutrient conditions
Li, S. H.-J.; Li, Z.; Park, J. O.; King, C. G.; Rabinowitz, J. D.; Wingreen, N. S.; Gitai, Z.
10.1101/224204 — microbiology — Posted on 2018-01-21
754 HDL-AuNPs-BMS nanoparticle conjugates as molecularly targeted therapy for leukemia
Shen, N.; Yan, F.; Pang, J.; Gao, Z.; Al-Kali, A.; Haynes, C. L.; Litzow, M. R.; Liu, S.
10.1101/250985 — cancer biology — Posted on 2018-01-20
755 Generation of a novel growth-enhanced and reduced environmental impact transgenic pig strain
Zhang, X.; Li, Z.; Yang, H.; Liu, D.; Cai, G.; Li, G.; Mo, J.; Wang, D.; Zhong, C.; Wang, H.; Sun, Y.; Shi, J.; Zheng, E.; Meng, F.; Zhang, M.; He, X.; Zhou, R.; Zhang, J.; Huang, M.; Zhang, R.; Li, N.; Zhe, F.; Yang, J.; Wu, Z.
10.1101/250902 — biochemistry — Posted on 2018-01-20
757 Listeria monocytogenes virulence factors are secreted in biologically active Extracellular Vesicles
Coelho, C.; Brown, L.; Maryam, M.; Burnet, M. C.; Kyle, J. E.; Heyman, H. M.; Vij, R.; Ramirez, J.; Prados-Rosales, R.; Lauvau, G.; Nakayasu, E. S.; Brady, N. R.; Hamacher-Brady, A.; Coppens, I.; Casadevall, A.
10.1101/210906 — microbiology — Posted on 2018-01-20
758 Genome-wide Meta-analysis of 158,000 Individuals of European Ancestry Identifies Three Loci Associated with Chronic Back Pain
Suri, P.; Palmer, M. R.; Tsepilov, Y. A.; Freidin, M. B.; Boer, C. G.; Yau, M. S.; Evans, D. S.; Gelemanovic, A.; Bartz, T. M.; Nethander, M.; Arbeeva, L.; Karssen, L.; Neogi, T.; Campbell, A.; Mellstrom, D.; Ohlsson, C.; Marshall, L. M.; Orwoll, E.; Uitterlinden, A.; Rotter, J. I.; Lauc, G.; Psaty, B. M.; Karlsson, M. K.; Lane, N. E.; Jarvik, G. P.; Polasek, O.; Hochberg, M.; Jordan, J. M.; Van Meurs, J. B.; Jackson, R.; Nielson, C. M.; Mitchell, B. D.; Smith, B. H.; Hayward, C.; Smith, N. L.; Aulchenko, Y. S.; Williams, F. M.
10.1101/244483 — genomics — Posted on 2018-01-20
760 Marine proteorhodopsins rival photosynthesis in solar energy capture
Gomez-Consarnau, L.; Levine, N. M.; Cutter, L. S.; Wang, D.; Seegers, B.; Aristegui, J.; Fuhrman, J. A.; Gasol, J. M.; Sanudo-Wilhelmy, S. A.
10.1101/231167 — ecology — Posted on 2018-01-20
762 Microtubule dynamics regulates mitochondrial fission
Mehta, K.; Chug, M. K.; Jhunjhunwala, S.; Ananthanarayanan, V.
10.1101/178913 — cell biology — Posted on 2018-01-20
763 The Chlamydia type III effector TarP alters the dynamics and organization of host cell focal adhesions
Pedrosa, A. T.; Nogueira, A. T.; Thwaites, T. R.; Aaron, J.; Chew, T.-L.; Carabeo, R. A.
10.1101/250563 — cell biology — Posted on 2018-01-20
765 Irreversible temperature gating in trpv1 sheds light on channel activation
Sanchez-Moreno, A.; Guevara-Hernandez, E.; Contreras-Cervera, R.; Rangel-Yescas, G.; Ladron-de-Guevara, E.; Rosenbaum, T.; Islas, L. D.
10.1101/251124 — biophysics — Posted on 2018-01-20
767 Improved phylogenetic resolution within Siphonophora (Cnidaria) with implications for trait evolution
Munro, C.; Siebert, S.; Zapata, F.; Howison, M.; Damian-Serrano, A.; Church, S. H.; Goetz, F. E.; Pugh, P. R.; Haddock, S. H. D.; Dunn, C. W.
10.1101/251116 — evolutionary biology — Posted on 2018-01-20
768 Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer
Kumar, B.; Rosenberg, A. Z.; Choi, S. M.; Fox-Talbot, K.; De Marzo, A. M.; Nonn, L.; Brennen, W. N.; Marchionni, L.; Halushka, M. K.; Lupold, S. E.
10.1101/251090 — cancer biology — Posted on 2018-01-20
769 Inference of CRISPR Edits from Sanger Trace Data
Hsiau, T.; Maures, T.; Waite, K.; Yang, J.; Kelso, R.; Holden, K.; Stoner, R.
10.1101/251082 — bioinformatics — Posted on 2018-01-20
772 Assessing Combinability of Phylogenomic Data using Bayes Factors
Neupane, S.; Fucikova, K.; Lewis, L. A.; Kuo, L.; Chen, M.-H.; Lewis, P.
10.1101/250969 — evolutionary biology — Posted on 2018-01-19
774 Equivalent high-resolution identification of neuronal cell types with single-nucleus and single-cell RNA-sequencing
Bakken, T. E.; Hodge, R. D.; Miller, J. M.; Yao, Z.; Nguyen, T. N.; Aevermann, B.; Barkan, E.; Bertagnolli, D.; Casper, T.; Dee, N.; Garren, E.; Goldy, J.; Gray, L. T.; Kroll, M.; Lasken, R. S.; Lathia, K.; Parry, S.; Rimorin, C.; Scheuermann, R. H.; Schork, N. J.; Shehata, S. I.; Tieu, M.; Phillips, J. W.; Bernard, A.; Smith, K. A.; Zeng, H.; Lein, E. S.; Tasic, B.
10.1101/239749 — neuroscience — Posted on 2018-01-19
777 HIF-2α is essential for carotid body development and function
Johnson, R.; Macias, D.; Lopez-Barneo, J.; Cowburn, A. S.; Torres-Torrelo, H.; Ortega-Saenz, P.
10.1101/250928 — bioinformatics — Posted on 2018-01-19
778 Efficient Homology Directed Repair by Cas9:DNA Localization and Cationic Polymeric Transfection in Mammalian Cells
Roche, P. J.; Gytz, H.; Hussain, F.; Cameron, C. J.; Paquette, D.; Blanchette, M.; Dostie, J.; Nagar, B.; Akavia, U. D.
10.1101/248179 — biochemistry — Posted on 2018-01-19
780 Molecular crypsis by pathogenic fungi using human factor H. A numerical model
Lang, S. N.; Germerodt, S.; Glock, C.; Skerka, C.; Zipfel, P.; Schuster, S.
10.1101/250662 — systems biology — Posted on 2018-01-19
781 Pathogenic mycobacteria manipulate host low density lipoprotein metabolism
Johansen, M. D.; Hortle, E.; Kasparian, J.; Romero, A.; Novoa, B.; Figueras, A.; Britton, W.; de Silva, K.; Purdie, A. C.; Oehlers, S. H.
10.1101/250548 — immunology — Posted on 2018-01-19
785 Sharq, a versatile preprocessing and QC pipeline for Single Cell RNA-seq
Candelli, T.; Lijnzaad, P.; Muraro, M. J.; van Oudenaarden, A.; Margaritis, T.; Holstege, F.
10.1101/250811 — bioinformatics — Posted on 2018-01-19
787 Seidr: A toolkit for calculation of crowd networks
Schiffthaler, B.; Serrano, A.; Delhomme, N.; Street, N. R.
10.1101/250696 — bioinformatics — Posted on 2018-01-19
790 Data-driven models of dominantly-inherited Alzheimer’s disease progression
Oxtoby, N. P.; Young, A. L.; Cash, D. M.; Benzinger, T. L. S.; Fagan, A. M.; Morris, J. C.; Bateman, R. J.; Fox, N. C.; Schott, J. M.; Alexander, D. C.
10.1101/250654 — neuroscience — Posted on 2018-01-19
791 Fatigue influences the recruitment, but not structure, of muscle synergies
Ortega-Auriol, P.; Besier, T. F.; Byblow, W. D.; McMorland, A. J.
10.1101/250522 — neuroscience — Posted on 2018-01-19
792 Quantitative analysis of synaptic pathology and neuroinflammation: an initial study in a female rhesus monkey model of the “synaptic” phase of Alzheimer’s disease
Beckman, D.; Donis-Cox, K.; Ott, S.; Roberts, M.; Novik, L.; Janssen, W. G.; Bliss-Moreau, E.; Rudebeck, P. H.; Baxter, M. G.; Morrison, J. H.
10.1101/251025 — neuroscience — Posted on 2018-01-19
793 Metagenomics reveals diet-specific specialization in fungus gardens of grass- and dicot-cutter ants
Khadempour, L.; Fan, H.; Keefover-Ring, K.; Carlos, C.; Nagamoto, N. S.; Dam, M. A.; Pupo, M. T.; Currie, C. R.
10.1101/250993 — microbiology — Posted on 2018-01-19
795 Differential Antiviral Activities of RSV Inhibitors in Human Airway Epithelium
Mirabelli, C.; Jaspers, M.; Boon, M.; Jorissen, M.; Koukni, M.; Bardiot, D.; Chaltin, P.; Marchand, A.; Neyts, J.; Jochmans, D.
10.1101/250639 — microbiology — Posted on 2018-01-19
796 Identification of rare de novo epigenetic variations in congenital disorders
Barbosa, M.; Joshi, R. S.; Garg, P.; Martin-Trujillo, A.; Patel, N.; Jadhav, B.; Watson, C. T.; Gibson, W.; Chetnik, K.; Tessereau, C.; Mei, H.; de Rubeis, S.; Reichert, J.; Lopes, F.; Vissers, L.; Kleefstra, T.; Grice, D. E.; Edelmann, L.; Soares, G.; Maciel, P.; Brunner, H. G.; Buxbaum, J. D.; Gelb, B. D.; Sharp, A.
10.1101/250787 — genomics — Posted on 2018-01-19
797 Human local adaptation of the TRPM8 cold receptor along a latitudinal cline
Key, F. M.; Abdul-Aziz, M. A.; Mundry, R.; Peter, B.; Sekar, A.; D Amato, M.; Dennis, M. Y.; Schmidt, J. M.; Andres, A. M.
10.1101/251033 — genetics — Posted on 2018-01-19
798 Mitogenomic data indicate admixture components of Asian Hun and Srubnaya origin in the Hungarian Conquerors
Neparaczki, E.; Maroti, Z.; Kalmar, T.; Kocsy, K.; Maar, K.; Bihari, P.; Nagy, I.; Fothi, E.; Pap, I.; Kustar, A.; Palfi, G.; Rasko, I.; Zink, A.; Torok, T.
10.1101/250688 — genetics — Posted on 2018-01-19
800 Assessing Combinability of Phylogenomic Data using Bayes Factors
Neupane, S.; Fucikova, K.; Lewis, L. A.; Kuo, L.; Chen, M.-H.; Lewis, P.
10.1101/250969 — evolutionary biology — Posted on 2018-01-19
801 Neonate gut and respiratory microbiota: coordinated development through time and space
Grier, A.; McDavid, A.; Wang, B.; Qui, X.; Java, J.; Bandyopadhyay, S.; Holden-Wiltse, J.; Kessler, H. A.; Gill, A. L.; Huyck, H.; Falsey, A. R.; Topham, D. J.; Scheible, K. M.; Caserta, M. T.; Pryhuber, G. S.; Gill, S. R.
10.1101/247122 — developmental biology — Posted on 2018-01-19
804 Single Cell Molecular Alterations Reveal Pathogenesis and Targets of Concussive Brain Injury
Arneson, D.; Zhuang, Y.; Byun, H. R.; Ahn, I. S.; Ying, Z.; Zhang, G.; Gomez-Pinilla, F.; Yang, X.
10.1101/250381 — systems biology — Posted on 2018-01-19
805 The Healthy Nevada Project: rapid recruitment for population health study
Grzymski, J. J.; Coppes, M. J.; Metcalf, J.; Galanopoulos, C.; Rowan, C.; Henderson, M.; Read, R. W.; Reed, H.; Lipp, B.; Miceli, D.; Rybarski, S.; Slonim, A.
10.1101/250274 — scientific communication and education — Posted on 2018-01-19
806 Expression of SULTR2;2 in the Arabidopsis bundle sheath is mediated by a highly conserved positive regulator
Kirschner, S.; Woodfield, H.; Prusko, K.; Koczor, M.; Gowik, U.; Hibberd, J. M.; Westhoff, P.
10.1101/250738 — plant biology — Posted on 2018-01-19
809 CSF biomarkers are differentially related to structural and functional changes in dementia of the Alzheimer’s type
Malpas, C. B.; Saling, M. M.; Velakoulis, D.; Desmond, P.; Hicks, R. J.; Zetterberg, H.; Blennow, K.; O'Brien, T. J.
10.1101/250449 — neuroscience — Posted on 2018-01-19
812 Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0
Sperschneider, J.; Dodds, P. N.; Gardiner, D. M.; Singh, K. B.; Taylor, J. M.
10.1101/250464 — bioinformatics — Posted on 2018-01-19
813 Treemmer: a tool to reduce large phylogenetic datasets with minimal loss of diversity
Menardo, F.; Loiseau, C.; Brites, D.; Coscolla, M.; Gygli, S.; Rutaihwa, L.; Trauner, A.; Beisel, C.; Borrell, S.; Gagneux, S.
10.1101/249391 — bioinformatics — Posted on 2018-01-19
817 Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention
Inouye, M.; Abraham, G.; Nelson, C. P.; Wood, A. M.; Sweeting, M. J.; Dudbridge, F.; Lai, F. Y.; Kaptoge, S.; Brozynska, M.; Wang, T.; Ye, S.; Webb, T. R.; Rutter, M. K.; Tzoulaki, I.; Patel, R. S.; Loos, R. J.; Keavney, B.; Hemingway, H.; Thompson, J.; Watkins, H.; Deloukas, P.; Di Angelantonio, E.; Butterworth, A. S.; Danesh, J.; Samani, N. J.
10.1101/250712 — genetics — Posted on 2018-01-19
819 Expression of SULTR2;2 in the Arabidopsis bundle sheath is mediated by a highly conserved positive regulator
Hibberd, J. M.; Kirschner, S.; Woodfield, H.; Prusko, K.; Koczor, M.; Gowik, U.; Westhoff, P.
10.1101/250738 — plant biology — Posted on 2018-01-19
820 Synergistic binding of bHLH transcription factors to the promoter of the maize NADP-ME gene used in C4 photosynthesis is based on an ancient code found in the ancestral C3 state
Borba, A. R.; Serra, T. S.; Gorska, A.; Gouveia, P.; Cordeiro, A. M.; Reyna-Llorens, I.; Knerova, J.; Barros, P. M.; Abreu, I. A.; Oliveira, M. M. O.; Hibberd, J. M.; Saibo, N. J. M.
10.1101/230136 — plant biology — Posted on 2018-01-19
822 BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior
Maynard, K. R.; Hobbs, J. W.; Phan, B. N.; Gupta, A.; Rajpurohit, S.; Williams, C.; Rajpurohit, N.; Shin, J. H.; Jaffe, A. E.; Martinowich, K.
10.1101/250332 — neuroscience — Posted on 2018-01-19
824 Systems biology analysis of mitogen activated protein kinase inhibitor resistance in malignant melanoma
Zecena, H.; Tveit, D.; Wang, Z.; Farhat, A.; Panchal, P.; Liu, J.; Singh, S.; Sanghera, A.; Bainiwal, A.; Teo, S.; Meyskens, F.; Liu-Smith, F.; Filipp, F. V.
10.1101/231142 — systems biology — Posted on 2018-01-19
825 Genome-encoded Cytoplasmic Double-Stranded RNAs, Found in C9ORF72 ALS-FTD Brain, Provoke Propagated Neuronal Death
Rodriguez, S.; Schrank, B. R.; Sahin, A.; Al-Lawati, H.; Constantino, I.; Benz, E.; Fard, D.; Albers, A. D.; Cao, L.; Gomez, A. C.; Ratti, E.; Cudkowicz, M.; Frosch, M. P.; Talkowski, M.; Sorger, P. K.; Hyman, B. T.; Albers, M. W.
10.1101/248328 — neuroscience — Posted on 2018-01-19
826 Passive Audio Vocal Capture and Measurement in the Evaluation of Selective Mutism
Xu, H.; Stroud, J.; Jozanovic, R.; Clucas, J.; Son, J.; Koo, B.; Schwarz, J.; Klein, A.; Busman, R.; Milham, M. P.
10.1101/250308 — neuroscience — Posted on 2018-01-19
827 Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration
Challis, R. C.; Kumar, S. R.; Chan, K. Y.; Challis, C.; Jang, M. J.; Rajendran, P. S.; Tompkins, J. D.; Shivkumar, K.; Deverman, B. E.; Gradinaru, V.
10.1101/246405 — neuroscience — Posted on 2018-01-19
828 MicroRNA-122 supports robust innate immunity in hepatocytes by suppressing STAT3 phosphorylation
Xu, H.; Xu, S.-J.; Xie, S.-J.; Zhang, Y.; Yang, J.-H.; Zhang, W.-Q.; Zheng, M.-N.; Zhou, H.; Qu, L.-H.
10.1101/250746 — molecular biology — Posted on 2018-01-19
833 Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors
Rohde, J. M.; Brimacombe, K. R.; Liu, L.; Pacold, M. E.; Yasgar, A.; Cheff, D. M.; Lee, T. D.; Rai, G.; Baljinnyam, B.; Li, Z.; Simeonov, A.; Hall, M. D.; Shen, M.; Sabatini, D. M.; Boxer, M. B.
10.1101/250340 — cancer biology — Posted on 2018-01-19
835 Evaluating Cell Identity from Transcription Profiles
Mah, N.; Taskova, K.; El Amrani, K.; Hariharan, K.; Kurtz, A.; Andrade-Navarro, M. A.
10.1101/250431 — bioinformatics — Posted on 2018-01-19
836 Predicting E. coli concentrations using limited qPCR deployments at Chicago beaches
Lucius, N.; Rose, K.; Osborn, C.; Sweeney, M. E.; Chesak, R.; Little, D. Y.; Beslow, S.; Schenk, T.
10.1101/250480 — bioinformatics — Posted on 2018-01-19
840 Epigenome-wide association in adipose tissue from the METSIM cohort
Orozco, L. D.; Farrell, C.; Hale, C.; Rubbi, L.; Rinaldi, A.; Civelek, M.; Pam, C.; Lam, L.; Montoya, D.; Edillor, C.; Seldin, M.; Boehnke, M.; Mohlke, K.; Jacobsen, S.; Kuusisto, J.; Laakso, M.; Lusis, A. J.; Pellegrini, M.
10.1101/223495 — genetics — Posted on 2018-01-19
841 Size-dependent segregation controls macrophage phagocytosis of antibody-opsonized targets
Bakalar, M. H.; Joffe, A. M.; Schmid, E.; Son, S.; Podolski, M.; Fletcher, D. A.
10.1101/250373 — cell biology — Posted on 2018-01-19
842 Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma
Yuan, J.; Levitin, H. M.; Frattini, V.; Bush, E. C.; Samanamud, J.; Ceccarelli, M.; Dovas, A.; Zanazzi, G.; Canoll, P.; Bruce, J. N.; Lasorella, A.; Iavarone, A.; Sims, P. A.
10.1101/250704 — cancer biology — Posted on 2018-01-19
845 Dopaminergic drug effects on probability weighting during risky decision-making
Ojala, K. E.; Janssen, L. K.; Hashemi, M. M.; Timmer, M. H. M.; Geurts, D. E. M.; ter Huurne, N. P.; Cools, R.; Sescousse, G.
10.1101/171587 — neuroscience — Posted on 2018-01-19
846 ESCRT-III acts in scissioning new peroxisomes from the ER
Mast, F. D.; Herricks, T.; Strehler, K. M.; Miller, L. R.; Saleem, R. A.; Rachubinski, R. A.; Aitchison, J. D.
10.1101/147603 — cell biology — Posted on 2018-01-19
847 Opportunities And Obstacles For Deep Learning In Biology And Medicine
Ching, T.; Himmelstein, D. S.; Beaulieu-Jones, B. K.; Kalinin, A. A.; Do, B. T.; Way, G. P.; Ferrero, E.; Agapow, P.-M.; Zietz, M.; Hoffman, M. M.; Xie, W.; Rosen, G. L.; Lengerich, B. J.; Israeli, J.; Lanchantin, J.; Woloszynek, S.; Carpenter, A. E.; Shrikumar, A.; Xu, J.; Cofer, E. M.; Lavender, C. A.; Turaga, S. C.; Alexandari, A. M.; Lu, Z.; Harris, D. J.; DeCaprio, D.; Qi, Y.; Kundaje, A.; Peng, Y.; Wiley, L. K.; Segler, M. H. S.; Boca, S. M.; Swamidass, S. J.; Huang, A.; Gitter, A.; Greene, C. S.
10.1101/142760 — bioinformatics — Posted on 2018-01-19
849 Loop Assembly: a simple and open system for recursive fabrication of DNA circuits
Pollak, B.; Cerda, A.; Delmans, M.; Alamos, S.; Moyano, T.; West, A.; Gutierrez, R. A.; Patron, N.; Federici, F.; Haseloff, J.
10.1101/247593 — synthetic biology — Posted on 2018-01-18
851 Inherited BRCA1 epimutation as a novel cause of breast and ovarian cancer
Evans, D. G. R.; van Veen, E. M.; Byers, H. J.; Wallace, A. J.; Ellingford, J. M.; Beaman, G.; Santoyo-Lopez, J.; Aitman, T. J.; Eccles, D. M.; Lalloo, F. I.; Smith, M. J.; Newman, W. G.
10.1101/246934 — genetics — Posted on 2018-01-18
854 The expa1-1 mutant reveals a new biophysical lateral root organogenesis checkpoint
Ramakrishna, P.; Rance, G. A.; Vu, L. D.; Murphy, E.; Swarup, K.; Moirangthem, K.; Jorgensen, B.; van de Cotte, B.; Goh, T.; Lin, Z.; Voss, U.; Beeckman, T.; Bennett, M. J.; Gevaert, K.; De Smet, I.
10.1101/249961 — plant biology — Posted on 2018-01-18
855 Single-cell transcriptional dynamics of flavivirus infection
Zanini, F.; Pu, S.-Y.; Bekerman, E.; Einav, S.; Quake, S. R.
10.1101/203331 — microbiology — Posted on 2018-01-18
857 Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy
Arbel, H.; Fisher, W. W.; Hammonds, A. S.; Wan, K. H.; Park, S.; Weiszmann, R.; Keranen, S.; Henriquez, C.; Solari, O. S.; Bickel, P. J.; Biggin, M.; Celniker, S. E.; Brown, J. B.
10.1101/250241 — genomics — Posted on 2018-01-18
861 Parallels between experimental and natural evolution of legume symbionts
Clerissi, C.; Touchon, M.; Capela, D.; Tang, M.; Cruveiller, S.; Parker, M. A.; Moulin, L.; Masson-Boivin, C.; Rocha, E. P. C.
10.1101/250159 — evolutionary biology — Posted on 2018-01-18
862 Measuring mosquito-borne viral suitability and its implications for Zika virus transmission in Myanmar
Perez, P. N.; Alcantara, L. C.; Obolski, U.; Maia de Lima, M.; Ashley, E.; Smithuis, F.; Horby, P.; Maude, R. J.; Lourenco, J.
10.1101/231373 — epidemiology — Posted on 2018-01-18
864 MicroRNA regulation of the MRN complex impacts DNA damage, cellular senescence and angiogenic signaling
Espinosa-Diez, C.; Wilson, R.; Chatterjee, N.; Hudson, C.; Ruhl, R.; Hipfinger, C.; Helms, E.; Khan, O. F.; Anderson, D. G.; Anand, S.
10.1101/132258 — cancer biology — Posted on 2018-01-18
865 A Multifactorial Model of T Cell Expansion and Durable Clinical Benefit in Response to a PD-L1 Inhibitor
Leiserson, M. D.; Syrgkanis, V.; Gilson, A.; Dudik, M.; Bajorin, D. F.; Rosenberg, J.; Funt, S.; Snyder, A.; Mackey, L.
10.1101/231316 — cancer biology — Posted on 2018-01-18
866 Evolution of an intratumoral ecology susceptible to successive treatment in breast cancer xenografts
Kim, H.; Kumar, P.; Menghi, F.; Noorbakhsh, J.; Cerveira, E.; Ryan, M.; Zhu, Q.; Ananda, G.; George, J.; Chen, H.; Mockus, S.; Zhang, C.; Yang, Y.; Keck, J.; Karuturi, R. K. M.; Bult, C. J.; Lee, C.; Liu, E. T.; Chuang, J. H.
10.1101/249797 — cancer biology — Posted on 2018-01-18
867 Enzyme Intermediates Captured "on-the-fly" by Mix-and-Inject Serial Crystallography
Olmos, J.; Pandey, S.; Martin-Garcia, J. M.; Calvey, G.; Katz, A.; Knoska, J.; Kupitz, C.; Hunter, M. S.; Liang, M.; Oberthuer, D.; Yefanov, O.; Wiedorn, M.; Heymann, M.; Holl, M.; Pande, K.; Barty, A.; Miller, M. D.; Stern, S.; Roy-Chowdhury, S.; Coe, J. D.; Nagaratnam, N.; Zook, J.; Verburgt, J.; Norwood, T.; Poudyal, I.; Xu, D.; Koglin, J.; Seaberg, M.; Zhao, Y.; Bajt, S.; Grant, T.; Mariani, V.; Nelson, G.; Subramanian, G.; Bae, E.; Fromme, R.; Fung, R.; Schwander, P.; Frank, M.; White, T.; Weierstall, U.; Zatsepin, N.; Spence, J.; Fromme, P.; Chapman, H. N.; Pollack, L.; Tremblay, L.; Our
10.1101/202432 — biophysics — Posted on 2018-01-18
868 Non-coding Transcriptome Maps Across Twenty Tissues of the Korean Black Chicken, Yeonsan Ogye
Hong, H.; Chai, H.-H.; Nam, K.; Lim, D.; Lee, K.-T.; Do, Y. J.; Cho, C.-Y.; Nam, J.-W.
10.1101/223644 — bioinformatics — Posted on 2018-01-18
870 Transgenic mouse lines expressing the 3xFLAG-dCas9 protein for enChIP analysis
Fujita, T.; Kitaura, F.; Oji, A.; Tanigawa, N.; Yuno, M.; Ikawa, M.; Taniuchi, I.; Fujii, H.
10.1101/221820 — biochemistry — Posted on 2018-01-18
871 Passive Audio Vocal Capture and Measurement in the Evaluation of Selective Mutism
Xu, H.; Stroud, J.; Jozanovic, R.; Clucas, J.; Son, J.; Koo, B.; Schwarz, J.; Klein, A.; Busman, R.; Milham, M. P.
10.1101/250308 — neuroscience — Posted on 2018-01-18
872 Laboratory and Molecular Surveillance of Paediatric Typhoidal Salmonella in Nepal: Antimicrobial Resistance and Implications for Vaccine Policy
Britto, C.; Dyson, Z. A.; Duchene, S.; Carter, M.; Gurung, M.; Kelly, D.; Murdoch, D.; Ansari, I.; Thorson, S.; Shrestha, S.; Adhikari, N.; Dougan, G.; Holt, K.; Pollard, A.
10.1101/250142 — molecular biology — Posted on 2018-01-18
873 Cytokinin signaling in Mycobacterium tuberculosis
Samanovic, M. I.; Hsu, H.-C.; Jones, M. B.; Jones, V.; McNeil, M. R.; Becker, S. H.; Jordan, A. T.; Strnad, M.; Xu, C.; Jackson, M.; Li, H.; Darwin, K. H.
10.1101/168815 — microbiology — Posted on 2018-01-18
878 Dynein catch bond as a mediator of codependent bidirectional cellular transport
Puri, P.; Gupta, N.; Chandel, S.; Naskar, S.; Nair, A.; Chaudhuri, A.; Mitra, M. K.; Muhuri, S.
10.1101/250175 — biophysics — Posted on 2018-01-18
879 Experimental Directory Structure (Exdir): An alternative to HDF5 without introducing a new file format
Dragly, S.-A.; Hobbi Mobarhan, M.; Lepperod, M.; Tennoe, S.; Hafting, T.; Fyhn, M.; Malthe-Sorenssen, A.
10.1101/249979 — bioinformatics — Posted on 2018-01-18
881 A Toolbox for Discrete Modelling of Cell Signalling Dynamics
Paterson, Y. Z.; Shorthouse, D.; Pleijzier, M. W.; Piterman, N.; Bendtsen, C.; Hall, B. A.; Fisher, J.
10.1101/249888 — systems biology — Posted on 2018-01-18
882 Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers
Guo, T.; Li, L.; Zhong, Q.; Rupp, N. J.; Charmpi, K.; Wong, C. E.; Wagner, U.; Rueschoff, J. H.; Jochum, W.; Fankhauser, C.; Saba, K.; Poyet, C.; Wild, P. J.; Aebersold, R.; Beyer, A.
10.1101/250167 — systems biology — Posted on 2018-01-18
887 Audio-tactile and peripersonal space processing around the trunk in human parietal and temporal cortex: an intracranial EEG study
Bernasconi, F.; Noel, J.-P.; Park, H.; Faivre, N.; Seeck, M.; Spinelli, L.; Schaller, K.; Blanke, O.; Serino, A.
10.1101/249078 — neuroscience — Posted on 2018-01-18
890 The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1
Ernst, R.; Gecht, M.; Fischer, S.; Seybert, A.; Frangakis, A. S.; Stelzer, E.; Covino, R.; Hummer, G.; Hofbauer, H. F.
10.1101/250019 — biochemistry — Posted on 2018-01-18
892 Reduced expression of C/EBPβ-LIP extends health- and lifespan in mice
Müller, C.; Zidek, L. M.; Ackermann, T.; de Jong, T.; Liu, P.; Kliche, V.; Zaini, M. A.; Kortman, G.; Harkema, L.; Verbeek, D. S.; Tuckermann, J. P.; von Maltzahn, J.; de Bruin, A.; Wang, Z.-Q.; Guryev, V.; Calkhoven, C. F.
10.1101/250100 — cell biology — Posted on 2018-01-18
893 Improving the Generation and Selection of Virtual Populations in Quantitative Systems Pharmacology Models
Rieger, T. R.; Allen, R. J.; Bystricky, L.; Chen, Y.; Colopy, G.; Cui, Y.; Gonzalez, A.; Liu, Y.; White, R.; Everett, R.; Banks, H. T.; Musante, C. J.
10.1101/196089 — pharmacology and toxicology — Posted on 2018-01-18
894 Complete avian malaria parasite genomes reveal features associated with lineage specific evolution in birds and mammals
Boehme, U.; Otto, T. D.; Cotton, J.; Steinbiss, S.; Sanders, M.; Oyola, S. O.; Nicot, A.; Gandon, S.; Patra, K. P.; Herd, C.; Bushell, E.; Modrzynska, K. K.; Billker, O.; Vinetz, J. M.; Rivero, A.; Newbold, C. I.; Berriman, M.
10.1101/086504 — genomics — Posted on 2018-01-18
897 Micro-hotspots of Risk in Urban Cholera Epidemics
Azman, A.; Luquero Alcalde, F. J.; Salje, H.; Naibei, N.; Adalbert, N.; Ali, M.; Bertuzzo, E.; Finger, F.; Toure, B.; Massing, L. A.; Ramazani, R.; Cardon, A.; Saga, B.; Allan, M.; Olson, D.; Leglise, J.; Porten, K.; Lessler, J.
10.1101/248476 — epidemiology — Posted on 2018-01-18
898 The PrEP Care Continuum and Racial Disparities in HIV Incidence among Men Who Have Sex with Men
Jenness, S. M.; Maloney, K. M.; Smith, D. K.; Hoover, K. W.; Goodreau, S. M.; Rosenberg, E. S.; Weiss, K. M.; Liu, A. Y.; Rao, D.; Sullivan, P. S.
10.1101/249540 — epidemiology — Posted on 2018-01-18
901 Observation weights to unlock bulk RNA-seq tools for zero inflation and single-cell applications
Van den Berge, K.; Perraudeau, F.; Soneson, C.; Love, M. I.; Risso, D.; Vert, J.-P.; Robinson, M. D.; Dudoit, S.; Clement, L.
10.1101/250126 — bioinformatics — Posted on 2018-01-18
903 Quantitative Trait Loci Controlling Phytophthora cactorum Resistance in the Cultivated Octoploid Strawberry (Fragaria x ananassa)
Nellist, C. F.; Vickerstaff, R.; Sobczyk, M. K.; Marina-Montes, C.; Brain, P.; Wilson, F. M.; Simpson, D. W.; Whitehouse, A. B.; Harrison, R.
10.1101/249573 — plant biology — Posted on 2018-01-18
904 In vivo monitoring of plant small GTPase activation using a Förster resonance energy transfer biosensor
Won, H. L.; Akamatsu, A.; Wang, Q.; Higuchi, M.; Matsuda, T.; Okuda, J.; Kosami, K.-i.; Inada, N.; Kawasaki, T.; Nagawa, S.; Tan, L.; Kawano, Y.; Shimamoto, K.
10.1101/249938 — plant biology — Posted on 2018-01-18
905 The expa1-1 mutant reveals a new biophysical lateral root organogenesis checkpoint
Ramakrishna, P.; Rance, G. A.; Vu, L. D.; Murphy, E.; Swarup, K.; Moirangthem, K.; Jorgensen, B.; van de Cotte, B.; Goh, T.; Lin, Z.; Voss, U.; Beeckman, T.; Bennett, M. J.; Gevaert, K.; De Smet, I.
10.1101/249961 — plant biology — Posted on 2018-01-18
906 Identification of powdery mildew resistance QTL in Fragaria x ananassa
Cockerton, H. M.; Vickerstaff, R. J.; Wilson, F.; Karlstrom, A.; Sobczyk, M.; Passey, A. J.; He, J. Q.; McLeary, K. J.; Sargent, D. J.; Pakozdi, K.; Harrison, N.; Lumbreras Martinez, M.; Antanaviciute, L.; Simpson, D. W.; Harrison, R. J.
10.1101/196485 — pathology — Posted on 2018-01-18
909 Genetic potential for disease resistance in a critically endangered frog decimated by chytridiomycosis.
Kosch, T. A.; Silva, C. N. S.; Brannelly, L. A.; Roberts, A.; Lau, Q.; Berger, L.; Skerratt, L. F.
10.1101/247999 — genomics — Posted on 2018-01-18
910 TAS2R38 predisposition to bitter taste associated with differential changes in vegetable intake in response to a community-based dietary intervention
Calancie, L.; Keyserling, T. C.; Smith-Taillie, L.; Robasky, K.; Patterson, C.; Ammerman, A. S.; Schisler, J. C.
10.1101/249763 — genomics — Posted on 2018-01-18
912 Shallow evolutionary divergence between two Andean hummingbirds: Speciation with gene flow?
Palacios, C.; Garcia-R, S.; Parra, J. L.; Cuervo, A. M.; Stiles, F. G.; McCormack, J. E.; Cadena, C. D.
10.1101/249755 — evolutionary biology — Posted on 2018-01-18
914 Evolution of an intratumoral ecology susceptible to successive treatment in breast cancer xenografts
Kim, H.; Kumar, P.; Menghi, F.; Noorbakhsh, J.; Cerveira, E.; Ryan, M.; Zhu, Q.; Ananda, G.; George, J.; Chen, H.; Mockus, S.; Zhang, C.; Yang, Y.; Keck, J.; Karuturi, R. K. M.; Bult, C. J.; Lee, C.; Liu, E. T.; Chuang, J. H.
10.1101/249797 — cancer biology — Posted on 2018-01-18
917 The Delirium and Population Health Informatics Cohort study protocol: ascertaining the determinants and outcomes from delirium in a whole population.
Davis, D.; Richardson, S.; Hornby, J.; Bowden, H.; Hoffmann, K.; Weston-Clarke, M.; Green, F.; Chaturvedi, N.; Hughes, A.; Kuh, D.; Sampson, E.; Mizoguchi, R.; Cheah, K. L.; Romain, M.; Sinha, A.; Jenkin, R.; Brayne, C.; MacLulllich, A.
10.1101/248559 — epidemiology — Posted on 2018-01-17
919 Mutations in efflux pump Rv1258c (Tap) cause resistance to pyrazinamide and other drugs in M. tuberculosis
Liu, J.; Shi, W.; Zhang, S.; Cassell, G.; Maslov, D.; Shur, K.; Bekker, O.; Danilenko, V.; Hao, X.; Zhang, Y.
10.1101/249102 — microbiology — Posted on 2018-01-17
920 Transcranial in vivo recording of neural activity in the rodent brain with near-infrared photoacoustic voltage-sensitive dye imaging
Kang, J.; Zhang, H. K.; Kadam, S. D.; Fedorko, J.; Valentine, H.; Yan, P.; Kang, J. U.; Rahmim, A.; Gjedde, A.; Loew, L. M.; Wong, D. F.; Boctor, E. M.
10.1101/202408 — neuroscience — Posted on 2018-01-17
924 Real-space refinement in Phenix for cryo-EM and crystallography
Afonine, P. V.; Poon, B. K.; Read, R. J.; Sobolev, O. V.; Terwilliger, T. C.; Urzhumtsev, A.; Adams, P. D.
10.1101/249607 — bioinformatics — Posted on 2018-01-17
926 FAIRsharing: working with and for the community to describe and link data standards, repositories and policies
Sansone, S.-A.; McQuilton, P.; Rocca-Serra, P.; Gonzalez-Beltran, A.; Izzo, M.; Lister, A.; Thurston, M.; FAIRsharing Community,
10.1101/245183 — scientific communication and education — Posted on 2018-01-17
927 PDE5 inhibition improves symptom-free survival and restores transverse tubule loss and catecholamine responsiveness in heart failure
Lawless, M.; Caldwell, J. L.; Radcliffe, E. J.; Madders, G. W.; Huthchings, D. C.; Woods, L. S.; Church, S. J.; Unwin, R. D.; Kirkwood, G. J.; Becker, L. K.; Pearman, C. M.; Taylor, R. F.; Eisner, D. A.; Dibb, K. M.; Trafford, A. W.
10.1101/248187 — physiology — Posted on 2018-01-17
930 Locally coordinated synaptic plasticity shapes cell-wide plasticity of visual cortex neurons in vivo
El-Boustani, S.; Ip, J. P. K.; Breton-Provencher, V.; Okuno, H.; Bito, H.; Sur, M.
10.1101/249706 — neuroscience — Posted on 2018-01-17
931 Cultivation and genomics of the first freshwater SAR11 (LD12) isolate
Henson, M. W.; Lanclos, V. C.; Faircloth, B. C.; Thrash, J. C.
10.1101/093567 — microbiology — Posted on 2018-01-17
932 scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
Clark, S. J.; Argelaguet, R.; Kapourani, C.-A.; Stubbs, T. M.; Lee, H. J.; Alda-Catalinas, C.; Krueger, F.; Sanguinetti, G.; Kelsey, G.; Marioni, J. C.; Stegle, O.; Reik, W.
10.1101/138685 — genomics — Posted on 2018-01-17
934 Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling
Cantu, C.; Felker, A.; Zimmerli, D.; Chiavacci, E.; Cabello, E. M.; Kirchgeorg, L.; Valenta, T.; Hausmann, G.; Ripoll, J.; Vilain, N.; Aguet, M.; Basler, K.; Mosimann, C.
10.1101/249680 — genetics — Posted on 2018-01-17
935 Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity
van Setten, J.; Brody, J. A.; Jamshidi, Y.; Swenson, B. R.; Butler, A. M.; Campbell, H.; Del Greco, F. M.; Evans, D. S.; Gibson, Q.; Gudbjartsson, D. F.; Kerr, K. F.; Krijthe, B. P.; Lyytikainen, L.-P.; Muller, C.; Muller-Nurasyid, M.; Nolte, I. M.; Padmanabhan, S.; Ritchie, M. D.; Robino, A.; Smith, A. V.; Steri, M.; Tanaka, T.; Teumer, A.; Trompet, S.; Ulivi, S.; Verweij, N.; Yin, X.; Arnar, D. O.; Asselbergs, F. W.; Bader, J. S.; Barnard, J.; Bis, J.; Blankenberg, S.; Boerwinkle, E.; Bradford, Y.; Buckley, B. M.; Chung, M. K.; Crawford, D.; den Hoed, M.; Denny, J.; Dominiczak, A. F.; Ehret,
10.1101/241489 — genetics — Posted on 2018-01-17
936 Phylodynamic assessment of intervention strategies for the West African Ebola virus outbreak
Dellicour, S.; Baele, G.; Dudas, G.; Faria, N. R.; Pybus, O. G.; Suchard, M. A.; Rambaut, A.; Lemey, P.
10.1101/163691 — epidemiology — Posted on 2018-01-17
939 Stochastic methods for inferring states of cell migration
Allen, R. J.; Welch, C.; Pankow, N.; Hahn, K.; Elston, T. C.
10.1101/249656 — cell biology — Posted on 2018-01-17
940 Dynamic action of the Sec machinery during initiation, protein translocation and termination revealed by single molecule fluorescence
Fessl, T.; Watkins, D.; Oatley, P.; Allen, W. J.; Corey, R. A.; Horne, J.; Baldwin, S. A.; Radford, S. E.; Collinson, I.; Tuma, R.
10.1101/248310 — biophysics — Posted on 2018-01-17
948 A structural mechanism for directing inverse agonism of PPARγ
Brust, R.; Shang, J.; Fuhrmann, J.; Bass, J.; Cano, A.; Heidari, Z.; Chrisman, I.; Blayo, A.-L.; Griffin, P.; Kamenecka, T.; Hughes, T.; Kojetin, D.
10.1101/245852 — biochemistry — Posted on 2018-01-17
949 Navigating in vitro bioactivity data: investigating available resources using model compounds
Ilmjarv, S.; Augsburger, F.; Bolleman, J. T.; Liechti, R.; Bridge, A.; Sandstrom, J.; Jaquet, V.; Xenarios, I.; Krause, K.-H.
10.1101/248898 — pharmacology and toxicology — Posted on 2018-01-17
951 Adaptation decorrelates shape representations
Mattar, M. G.; Olkkonen, M.; Epstein, R. A.; Aguirre, G. K.
10.1101/249045 — neuroscience — Posted on 2018-01-17
954 Multi-scale mapping along the auditory hierarchy using high-resolution functional UltraSound in the awake ferret
Bimbard, C.; Demene, C.; Girard, C.; Radtke-Schuller, S.; Shamma, S.; Tanter, M.; Boubenec, Y.
10.1101/249417 — neuroscience — Posted on 2018-01-17
957 Mutations in efflux pump Rv1258c (Tap) cause resistance to pyrazinamide and other drugs in M. tuberculosis
Zhang, Y.; Liu, J.; Zhang, S.; Cassell, G.; Maslov, D.; Hao, X.; Shur, K.; Bekker, O.; Danilenko, V.; Shi, W.
10.1101/249102 — microbiology — Posted on 2018-01-17
958 Structure of the Core of the Type Three Secretion System ExportApparatus
Kuhlen, L.; Abrusci, P.; Johnson, S.; Gault, J.; Deme, J.; Caesar, J.; Dietsche, T.; Mebrhatu, M. T.; Ganief, T.; Macek, B.; Wagner, S.; Robinson, C. V.; Lea, S. M.
10.1101/249128 — microbiology — Posted on 2018-01-17
960 Conserved collateral susceptibility networks in diverse clinical strains of Escherichia coli.
Podnecky, N. L.; Fredheim, E. G.; Kloos, J.; Sorum, V.; Primicerio, R.; Roberts, A. P.; Rozen, D. E.; Samuelsen, O.; Johnsen, P. J.
10.1101/248872 — microbiology — Posted on 2018-01-17
964 Linking heat attentions and the moment of LH surge in dairy cows - how close can we get?
Adriaens, I.; Saeys, W.; Lamberigts, C.; Berth, M.; Geerinckx, K.; Leroy, J.; De Ketelaere, B.; Aernouts, B.
10.1101/249169 — bioengineering — Posted on 2018-01-17
966 Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function
Adewoye, A. B.; Shrine, N.; Odenthal-Hesse, L.; Welsh, S.; Malarstig, A.; Jelinsky, S.; Kilty, I.; Tobin, M. D.; Hollox, E. J.; Wain, L. V.
10.1101/249508 — genetics — Posted on 2018-01-17
968 Enhanced photon collection enables four dimensional fluorescence nanoscopy of living systems
Masullo, L.; Boden, A.; Pennacchietti, F.; Coceano, G.; Ratz, M.; Testa, I.
10.1101/248880 — biophysics — Posted on 2018-01-17
970 Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing
Das, S.; Pettersson, F.; Behra, P. R. K.; Mallick, A.; Cheramie, M.; Shirreff, L.; Tanner DuCote, T.; Dasgupta, S.; Ennis, D. G.; Kirsebom, L.
10.1101/249532 — genomics — Posted on 2018-01-17
971 The genome of the biting midge Culicoides sonorensis and gene expression analyses of vector competence for Bluetongue virus
Morales Hojas, R.; Hinsley, M.; Armean, I. M.; Silk, R.; Harrup, L. E.; Gonzalez-Uriarte, A.; Veronesi, E.; Campbell, L.; Nayduch, D.; Saski, C.; Tabachnick, W. J.; Kersey, P.; Carpenter, S.; Fife, M.
10.1101/249482 — genomics — Posted on 2018-01-17
977 Predicting future learning from baseline network architecture
Mattar, M. G.; Wymbs, N. F.; Bock, A. S.; Aguirre, G. K.; Grafton, S. T.; Bassett, D. S.
10.1101/056861 — neuroscience — Posted on 2018-01-17
978 Spike sorting with Gaussian mixture models
Souza, B. C.; Lopes-dos-Santos, V.; Bacelo, J.; Tort, A. B.
10.1101/248864 — neuroscience — Posted on 2018-01-17
979 Growing oocyte specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR
Joh, K.; Matsuhisa, F.; Kitajima, S.; Nishioka, K.; Higashimoto, K.; Yatsuki, H.; Kono, T.; Koseki, H.; Soejima, H.
10.1101/249524 — molecular biology — Posted on 2018-01-17
981 Diverse spatial organization of photosynthetic membranes among purple nonsulfur bacteria
LaSarre, B.; Kysela, D. T.; Stein, B. D.; Ducret, A.; Brun, Y. V.; McKinlay, J. B.
10.1101/248997 — microbiology — Posted on 2018-01-17
983 Validation of a 14-drug microtitre plate that includes delamanid and bedaquiline for susceptibility testing of M. tuberculosis
Rancoita, P. M.; Cugnata, F.; Gibertoni Cruz, A. L.; Borroni, E.; Hoosdally, S. J.; Walker, T. M.; Grazian, C.; Davies, T. J.; Peto, T. E.; Crook, D. W.; Fowler, P. W.; Cirillo, D. M.; the CRyPTIC Consortium,
10.1101/244731 — microbiology — Posted on 2018-01-17
985 A centrosome asymmetry switch in fly neural stem cells
Gallaud, E.; Ramdas Nair, A.; Monnard, A.; Singh, P.; Pham, T.; Salvador Garcia, D.; Ferrand, A.; Cabernard, C.
10.1101/249375 — cell biology — Posted on 2018-01-17
986 Ostreococcus tauri is a high-lipid content green algae that extrudes clustered lipid droplets
Smallwood, C. R.; Chrisler, W.; Chen, J.-H.; Patello, E.; Thomas, M.; Boudreau, R.; Ekman, A.; Wang, H.; McDermott, G.; Evans, J. E.
10.1101/249052 — cell biology — Posted on 2018-01-17
987 Substrate deformations induce directed keratinocyte migration
Zarkoob, H.; Chinnathambi, S.; Selby, J. C.; Sander, E. A.
10.1101/249037 — biophysics — Posted on 2018-01-17
989 The Small β-barrel Domain: A Survey-based Structural Analysis
Youkharibache, P.; Veretnik, S.; Li, Q.; Stanek, K. A.; Mura, C.; Bourne, P. E.
10.1101/140376 — bioinformatics — Posted on 2018-01-17
990 Partially methylated domains are hallmarks of a cell specific epigenome topology
Salhab, A.; Nordström, K.; Kattler, K.; Ebert, P.; Ramirez, F.; Arrigoni, L.; Müller, F.; Cadenas, C.; Hengstler, J.; Lengauer, T.; Manke, T.; DEEP Consortium, ; Walter, J.
10.1101/249334 — bioinformatics — Posted on 2018-01-17
991 Accurate analysis of genuine CRISPR editing events with ampliCan
Labun, K.; Guo, X.; Chavez, A.; Church, G.; Gagnon, J. A.; Valen, E.
10.1101/249474 — bioinformatics — Posted on 2018-01-17
993 A novel system for online fertility monitoring based on milk progesterone
Adriaens, I.; Saeys, W.; Huybrechts, T.; Lamberigts, C.; Francois, L.; Geerinckx, K.; Leroy, J.; De Ketelaere, B.; Aernouts, B.
10.1101/248971 — bioengineering — Posted on 2018-01-17
995 Insects and incest: sib-mating tolerance in natural populations of a parasitoid wasp
Collet, M.; Amat, I.; Sauzet, S.; Auguste, A.; Fauvergue, X.; Mouton, L.; Desouhant, E.
10.1101/169268 — animal behavior and cognition — Posted on 2018-01-17
996 Loss of Trem2 in microglia leads to widespread disruption of cell co-expression networks in mouse brain
Carbajosa, G.; Malki, K.; Lawless, N.; Wang, H.; Ryder, J. W.; Wozniak, E.; Wood, K.; Mein, C. A.; Dobson, R. J. B.; Collier, D. A.; O'Neill, M. J.; Hodges, A. K.; Newhouse, S. J.
10.1101/248757 — systems biology — Posted on 2018-01-17
998 Cultivation and genomics of the first freshwater SAR11 (LD12) isolate
Henson, M. W.; Lanclos, V. C.; Faircloth, B. C.; Thrash, J. C.
10.1101/093567 — microbiology — Posted on 2018-01-17
999 Increased PHGDH expression uncouples hair follicle cycle progression and promotes inappropriate melanin accumulation
Mattaini, K. R.; Sullivan, M. R.; Lau, A. N.; Fiske, B. P.; Bronson, R. T.; Vander Heiden, M. G.
10.1101/249250 — developmental biology — Posted on 2018-01-17
1002 ExomeSlicer: a resource for the development and validation of exome-based clinical panels
Niazi, R.; Gonzalez, M. A.; Balciuniene, J.; Evans, P.; Sarmady, M.; Abou Tayoun, A. N.
10.1101/248906 — genomics — Posted on 2018-01-16
1003 Multiplex Assessment of Protein Variant Abundance by Massively Parallel Sequencing
Matreyek, K. A.; Starita, L. M.; Stephany, J. J.; Martin, B.; Chiasson, M. A.; Gray, V. E.; Kircher, M.; Khechaduri, A.; Dines, J. N.; Hause, R. J.; Bhatia, S.; Evans, W. E.; Relling, M. V.; Yang, W.; Shendure, J.; Fowler, D. M.
10.1101/211011 — genetics — Posted on 2018-01-16
1004 ORBIT: a new paradigm for geneticengineering of mycobacterial chromosomes
Murphy, K. C.; Nelson, S. J.; Nambi, S.; Papavinasasundaram, K.; Baer, C. E.; Sassetti, C. M.
10.1101/249292 — genetics — Posted on 2018-01-16
1005 miR-10b Deficiency Affords Atherosclerosis Resistance
Nakahara, M.; Kobayashi, N.; Oka, M.; Nakano, K.; Okamura, T.; Yuo, A.; Saeki, K.
10.1101/248641 — cell biology — Posted on 2018-01-16
1006 TMEM16F activation by Ca2+ triggers plasmalemma expansion and directs PD-1 trafficking
Bricogne, C.; Fine, M.; Pereira, P. M.; Sung, J.; Tijani, M.; Henriques, R.; Collins, M. K.; Hilgemann, D.
10.1101/249227 — cell biology — Posted on 2018-01-16
1007 Phosphorylation of GMFγ by c-Abl coordinates lamellipodial and focal adhesion dynamics
Gerlach, B. D.; Liao, G.; Tubbesing, K.; Rezey, A. C.; Wang, R.; Barroso, M.; Tang, D. D.
10.1101/248914 — cell biology — Posted on 2018-01-16
1008 Proteasome Substrate Capture and Gate Activation by Mycobacterium tuberculosis PafE
Hu, K.; Jastrab, J. B.; Zhang, S.; Kovach, A.; Zhao, G.; Darwin, K. H.; Li, H.
10.1101/249060 — biochemistry — Posted on 2018-01-16
1009 In search of non-coding driver mutations by deep sequencing of regulatory elements in colorectal cancer
Poulos, R. C.; Perera, D.; Packham, D.; Shah, A.; Janitz, C.; Pimanda, J. E.; Hawkins, N.; Ward, R. L.; Hesson, L. B.; Wong, J. W.
10.1101/249300 — biochemistry — Posted on 2018-01-16
1013 Methyl-CpG binding domain 2 (Mbd2) deficiency causes cognitive, social and emotional functional deficits
Lax, E.; Do-Carmo, S.; Enuka, Y.; Mahmood, N.; Rabbani, S.; Wang, L.; Cuello, C.; Hancock, W. W.; Yarden, Y.; Szyf, M.
10.1101/247197 — neuroscience — Posted on 2018-01-16
1014 Using Network Analysis to Localize the Epileptogenic Zone from Invasive EEG Recordings in Intractable Focal Epilepsy
Li, A.; Chennuri, B.; Subramanian, S.; Yaffe, R.; Gliske, S.; Stacey, W.; Norton, R.; Jordan, A.; Zaghloul, K. A.; Inati, S. K.; Agrawal, S.; Haagensen, J.; Hopp, J.; Atallah, C.; Johnson, E.; Crone, N.; Anderson, W. S.; Fitzgerald, Z.; Bulacio, J.; Gale, J. T.; Sarma, S. V.; Gonzalez-Martinez, J.
10.1101/247387 — neuroscience — Posted on 2018-01-16
1015 CityNet - Deep Learning Tools for Urban Ecoacoustic Assessment
Fairbrass, A. J.; Firman, M.; Williams, C.; Brostow, G. J.; Titheridge, H.; Jones, K. E.
10.1101/248708 — ecology — Posted on 2018-01-16
1019 Regulation of Eag by calcium/calmodulin controls presynaptic excitability in Drosophila
Bronk, P.; Kuklin, E. A.; Gorur-Shandilya, S.; Liu, C.; Wiggin, T. D.; Reed, M. L.; Marder, E.; Griffith, L. C.
10.1101/215293 — neuroscience — Posted on 2018-01-16
1022 Balance between mutually exclusive traits shifted by variants of a yeast transcription factor
Dorrity, M. W.; Cuperus, J. T.; Carlisle, J. A.; Fields, S.; Queitsch, C.
10.1101/117911 — genomics — Posted on 2018-01-16
1023 De novo mutations involved in post-transcriptional dysregulation contribute to six neuropsychiatric disorders
Mao, F.; Wang, L.; Zhao, X.; Xiao, L.; Li, X.; Liu, Q.; He, X.; Rao, R. C.; Li, J.; Teng, H.; Dou, Y.; Sun, Z.
10.1101/175844 — genomics — Posted on 2018-01-16
1026 Lattice defects induce microtubule self-renewal
Thery, M.; Schaedel, L.; Chretien, D.; Aumeier, C.; Gaillard, J.; Blanchoin, L.; John, K.
10.1101/249144 — cell biology — Posted on 2018-01-16
1028 Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury
Stumm, J.; Vallecillo Garcia, P.; vom Hofe-Schneider, S.; Ollitrault, D.; Schrewe, H.; Economides, A.; Marazzi, G.; Sassoon, D.; Stricker, S.
10.1101/249003 — cell biology — Posted on 2018-01-16
1029 Targeting histone deacetylase activity to arrest cell growth and promote neural differentiation in Ewing sarcoma
Souza, B. K.; Lopez, P. L. d. C.; Menegotto, P. R.; Vieira, I. A.; Kersting, N.; Abujamra, A. L.; Brunetto, A. T.; Brunetto, A. L.; Gregianin, L.; de Farias, C. B.; Thiele, C. J.; Roesler, R.
10.1101/191700 — cancer biology — Posted on 2018-01-16
1032 Identifying differentially methylated sites in samples with varying tumor purity
Häkkinen, A.; Alkodsi, A.; Facciotto, C.; Zhang, K.; Kaipio, K.; Leppä, S.; Carpen, O.; Grenman, S.; Hynninen, J.; Hietanen, S.; Lehtonen, R.; Hautaniemi, S.
10.1101/248781 — bioinformatics — Posted on 2018-01-16
1034 Beyond the ribosome: proteome-wide secretability studies using SECRiFY
Boone, M.; Ramasamy, P.; Maddelein, D.; Turan, D.; Vandermarliere, E.; Vranken, W.; Callewaert, N.
10.1101/241349 — molecular biology — Posted on 2018-01-16
1043 Structure and diversity of urinary cell-free DNA informative of host-pathogen interactions in human urinary tract infection
Burnham, P.; Dadhania, D.; Heyang, M.; Chen, F.; Westblade, L. F.; Suthanthiran, M.; Lee, J. R.; De Vlaminck, I.
10.1101/177402 — genomics — Posted on 2018-01-16
1048 Interfering with MIF-CD74 signalling on macrophages and dendritic cells with a peptide-based approach restores the immune response against metastatic melanoma.
Figueiredo, C. R.; Azevedo, R. A.; Mousdell, S.; Resende-Lara, P. T.; Ireland, L.; Santos, A.; Girola, N.; Cunha, R. L. O. R.; Schmid, M.; Polonelli, L.; Travassos, L. R.; Mielgo, A.
10.1101/248807 — cancer biology — Posted on 2018-01-16
1049 MaREA: Metabolic feature extraction, enrichment and visualization of RNAseq data
Graudenzi, A.; Maspero, D.; Isella, C.; Di Filippo, M.; Mauri, G.; Medico, E.; Antoniotti, M.; Damiani, C.
10.1101/248724 — bioinformatics — Posted on 2018-01-16
1054 The Viral protein Corona Directs Viral Pathogenesis and Amyloid Aggregation
Ezzat, K.; Pernemalm, M.; Palsson, S.; Roberts, T. C.; Jarver, P.; Dondalska, A.; Bestas, B.; Sobkowiak, M. J.; Levanen, B.; Skold, M.; Thompson, E. A.; Wood, M. J. A.; Power, U. F.; Masich, S.; Linden, A.; Sandberg, J. K.; Lehtio, J.; Spetz, A.-L.; Andaloussi, S. E.
10.1101/246785 — microbiology — Posted on 2018-01-16
1056 Utility of Attention-Deficit/Hyperactivity Disorder Trait Measure in Population Genetics: A Polygenic Risk Study
Burton, C. L.; Wright, L.; Shan, J.; Xiao, B.; Dupuis, A.; Goodale, T.; Shaheen, S.-M.; Corfield, E. C.; Arnold, P. D.; Schachar, R. J.; Crosbie, J.
10.1101/248484 — genetics — Posted on 2018-01-16
1057 Long-term prevalence data reveals spillover dynamics in a multi-host (Artemia), multi-parasite (Microsporidia) community
Lievens, E. J. P.; Rode, N. O.; Landes, J.; Segard, A.; Jabbour-Zahab, R.; Michalakis, Y.; Lenormand, T.
10.1101/248542 — ecology — Posted on 2018-01-16
1058 Zebrabase: An intuitive tracking solution for aquatic model organisms
Oltova, J.; Jindrich, J.; Skuta, C.; Svoboda, O.; Machonova, O.; Bartunek, P.
10.1101/248666 — developmental biology — Posted on 2018-01-16
1059 Recapitulation of human germline coding variation in an ultra-mutated infant leukemia
Gout, A. M.; Kotecha, R. S.; Kaur, P.; Abad, A.; Foley, B.; Carter, K. W.; Cole, C. H.; Bond, C. S.; Kees, U.; Waithman, J.; Cruickshank, M.
10.1101/248690 — cancer biology — Posted on 2018-01-16
1062 Whole Genome Sequencing and Rare Variant Analysis in Essential Tremor Families
Odgerel, Z.; Hernandez, N.; Park, J.; Ottman, R.; Louis, E.; Clark, L.
10.1101/248443 — genetics — Posted on 2018-01-16
1064 Reimplementation of the Potjans-Diesmann cortical microcircuit model: from NEST to Brian
Shimoura, R. O.; Kamiji, N. L.; Pena, R. F. d. O.; Cordeiro, V. L.; Ceballos, C. C.; Romaro, C.; Roque, A. C.
10.1101/248401 — systems biology — Posted on 2018-01-16
1066 Microbiota-independent antiviral protection conferred by aminoglycoside antibiotics
Gopinath, S.; Kim, M. V.; Rakib, T.; Wong, P. W.; van Zandt, M.; Barry, N. A.; Kaisho, T.; Goodman, A. L.; Iwasaki, A.
10.1101/248617 — immunology — Posted on 2018-01-16
1067 Risk Factors for Fouling Biomass: Evidence from Small Vessels in Australia
Lane, S.; Hollings, T.; Hayes, K. R.; McEnnulty, F. R.; Green, M.; Robinson, A. P.
10.1101/248567 — ecology — Posted on 2018-01-16
1068 USP7 cooperates with NOTCH1 to drive the oncogenic transcriptionalprogram in T cell leukemia
Ntziachristos, P.; Arcipowski, K.; Jin, Q.; Martinez, C. A.; Zhu, Y.; Gutierrez Diaz, B. T.; Wang, K.; Johnson, M.; Volk, A. G.; Wang, F.; wu, J.; Wang, H.; Sokirniy, I.; Thomas, P.; Goo, Y. A.; Abshiru, N.; Hijiya, N.; Peirs, S.; Vandamme, N.; Berx, G.; Goosens, S.; Marshall, S. A.; Randleman, E. J.; Takahashi, Y.-h.; Wang, L.; Bartom, E.; Collings, C.; Van Vlierberghe, P.; strikoudis, A.; kelly, S.; Ueberheide, B.; Mantis, C.; Kandela, I.; Bourquin, J.-P.; Bornhauser, B.; Serafin, V.; Bresolin, S.; Paganin, M.; Accordi, B.; Basso, G.; Kelleher, N. L.; Weinstock, J.; Kumar, S.; Crispino, J. D
10.1101/248427 — cancer biology — Posted on 2018-01-16
1071 Efficient Homology Directed Repair by Cas9:DNA Localization and Cationic Polymeric Transfection in Mammalian Cells
Roche, P. J.; Gytz, H.; Hussain, F.; Cameron, C. J.; Paquette, D.; Blanchette, M.; Dostie, J.; Nagar, B.; Akavia, U. D.
10.1101/248179 — biochemistry — Posted on 2018-01-16
1072 The evolution, distribution and diversity of endogenous circoviral elements
Dennis, T. P. W.; Souza, W. M.; Marsile-Medun, S.; Singer, J. B.; Wilson, S. J.; Gifford, R. J.
10.1101/207399 — evolutionary biology — Posted on 2018-01-16
1080 Spindly is Required for Rapid Migration of Human Cells.
Conte, C.; Baird, M.; Davidson, M. W.; Griffis, E. R.
10.1101/248393 — cell biology — Posted on 2018-01-15
1082 Chronic inflammation delays cell migration to villi in the intestinal epithelium
Muraro, D.; Parker, A.; Vaux, L.; Filippi, S.; Fletcher, A.; Watson, A.; Pin, C.; Maini, P.; Byrne, H.
10.1101/248344 — systems biology — Posted on 2018-01-15
1083 Cooperating yet distinct brain networks engaged during naturalistic paradigms: A meta-analysis of functional MRI results
Bottenhorn, K. L.; Flannery, J. S.; Boeving, E. R.; Riedel, M. C.; Eickhoff, S. B.; Sutherland, M. T.; Laird, A. R.
10.1101/165951 — neuroscience — Posted on 2018-01-15
1086 The representational dynamics of task and object processing in humans
Hebart, M. N.; Bankson, B. B.; Harel, A.; Baker, C. I.; Cichy, R. M.
10.1101/153684 — neuroscience — Posted on 2018-01-15
1093 Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies different amino acid preferences between peptide-based substrates and inhibitors.
Deu, E.; de Vries, L. E.; Sanchez, M. I.; Groborz, K.; Kuppens, L.; Poreba, M.; Lehmann, C.; Yuan, F.; Arastu-Kapur, S.; Bogyo, M.; Drag, M.
10.1101/246124 — biochemistry — Posted on 2018-01-15
1094 Loop Assembly: a simple and open system for recursive fabrication of DNA circuits
Pollak, B.; Cerda, A.; Delmans, M.; Alamos, S.; Moyano, T.; West, A.; Gutierrez, R. A.; Patron, N.; Federici, F.; Haseloff, J.
10.1101/247593 — synthetic biology — Posted on 2018-01-15
1097 A simulation study investigating power estimates in Phenome-Wide Association Studies
Verma, A.; Bradford, Y.; Dudek, S.; Verma, S. S.; Pendergrass, S. A.; Ritchie, M. D.
10.1101/115550 — genomics — Posted on 2018-01-15
1098 Resistance gene discovery and cloning by sequence capture and association genetics
Arora, S.; Steuernagel, B.; Chandramohan, S.; Long, Y.; Matny, O.; Johnson, R.; Enk, J.; Periyannan, S.; Hatta, M. A. M.; Athiyannan, N.; Cheema, J.; Yu, G.; Kangara, N.; Ghosh, S.; Szabo, L. J.; Poland, J.; Bariana, H.; Jones, J. D. G.; Bentley, A. R.; Ayliffe, M.; Olson, E.; Xu, S. S.; Steffenson, B. J.; Lagudah, E.; Wulff, B. B. H.
10.1101/248146 — genomics — Posted on 2018-01-15
1099 Identification of loci where DNA methylation potentially mediate genetic risk of type 1 diabetes
Ye, J.; Richardson, T. G.; McArdle, W.; Relton, C.; Gillespie, K. M.; Suderman, M.; Hemani, G.
10.1101/248260 — genomics — Posted on 2018-01-15
1103 Quantifying the performance of MEG source reconstruction using resting state data
Little, S. J.; Bonaiuto, J.; Meyer, S.; Lopez, J.; Bestmann, S.; Barnes, G.
10.1101/248252 — neuroscience — Posted on 2018-01-15
1105 Identifying long indels in exome sequencing data of patients with intellectual disability
Pajusalu, S.; Pfundt, R.; Vissers, L. E. L. M.; Kwint, M. P.; Reimand, T.; Ounap, K.; Veltman, J. A.; Hehir-Kwa, J.
10.1101/244756 — genomics — Posted on 2018-01-15
1110 Microbial biogeography of 1,000 geothermal springs in New Zealand
Power, J. F.; Carere, C. R.; Lee, C. K.; Wakerley, G. L.; Evans, D. W.; Button, M.; White, D.; Climo, M. D.; Hinze, A. M.; Morgan, X. C.; McDonald, I. R.; Cary, S. C.; Stott, M. B.
10.1101/247759 — microbiology — Posted on 2018-01-15
1116 HEx: a heterologous expression platform for the discovery of fungal natural products
Harvey, C. J.; Tang, M.; Schlecht, U.; Horecka, J.; Fischer, C. R.; Lin, H.-c.; Li, J.; Naughton, B.; Cherry, J.; Miranda, M.; Fuga Li, Y.; Chu, A. M.; Hennessy, J. R.; Vandova, G. A.; Inglis, D.; Aiyar, R.; Steinmetz, L. M.; Davis, R. W.; Medema, M. H.; Sattely, E.; Khosla, C.; St. Onge, R. P.; Tang, Y.; Hillenmeyer, M. E.
10.1101/247940 — synthetic biology — Posted on 2018-01-15
1117 Transcription factor dynamics reveals a circadian code for fat cell differentiation
Bahrami-Nejad, Z.; Zhao, M. L.; Tholen, S.; Hunerdosse, D.; Tkach, K. E.; van Schie, S.; Chung, M.; Teruel, M. N.
10.1101/245332 — physiology — Posted on 2018-01-15
1123 Beyond the ribosome: proteome-wide secretability studies using SECRiFY
Boone, M.; Ramasamy, P.; Maddelein, D.; Turan, D.; Vandermarliere, E.; Vranken, W.; Callewaert, N.
10.1101/241349 — molecular biology — Posted on 2018-01-15
1124 Arabidopsis thaliana populations support long-term maintenance and parallel expansions of related Pseudomonas pathogens
Karasov, T. L.; Almario, J.; Friedemann, C.; Ding, W.; Giolai, M.; Heavens, D.; Kersten, S.; Lundberg, D. S.; Neumann, M.; Regalado, J.; Neher, R. A.; Kemen, E.; Weigel, D.
10.1101/241760 — microbiology — Posted on 2018-01-15
1125 Viromic analysis of wastewater input to a river catchment reveals a diverse assemblage of RNA viruses
Adriaenssens, E.; Farkas, K.; Harrison, C.; Jones, D.; Allison, H. E.; McCarthy, A. J.
10.1101/248203 — microbiology — Posted on 2018-01-15
1128 Combining high-throughput micro-CT-RGB phenotyping and genome-wide association study to dissect the genetic architecture of tiller growth in rice
Wu, D.; Guo, Z.; Ye, J.; Liu, J.; Chen, G.; Zheng, J.; Yan, D.; Yang, X.; Xiong, X.; Liu, Q.; Niu, Z.; Xiong, L.; Yang, W.
10.1101/247841 — genetics — Posted on 2018-01-15
1129 Patterns of polymorphism, selection and linkage disequilibrium in the subgenomes of the allopolyploid Arabidopsis kamchatica
Paape, T.; Briskine, R. V.; Lischer, H. E. L.; Halstead-Nussloch, G.; Shimizu-Inatsugi, R.; Hatekayama, M.; Tanaka, K.; Nishiyama, T.; Sabirov, R.; Sese, J.; Shimizu, K. K.
10.1101/248195 — evolutionary biology — Posted on 2018-01-15
1130 Early diverging insect pathogenic fungi of the order Entomophthorales possess diverse and unique subtilisin-like serine proteases
Arnesen, J. A.; Malagocka, J.; Gryganskyi, A.; Grigoriev, I. V.; Voigt, K.; Stajich, J. E.; De Fine Licht, H. H. H.
10.1101/247858 — evolutionary biology — Posted on 2018-01-15
1131 In toto live imaging in scuttle fly Megaselia abdita reveals transitions towards a novel extraembryonic architecture.
Caroti, F.; Gonzalez Avalos, E.; Gonzalez Avalos, P.; Kromm, D.; Noeske, V.; Wosch, M.; Schütz, L.; Hufnagel, L.; Lemke, S.
10.1101/236364 — evolutionary biology — Posted on 2018-01-15
1132 Mutation accumulation differentially impacts ageing in mammalian tissues
Turan, Z. G.; Parvizi, P.; Donertas, H. M.; Tung, J.; Khaitovich, P.; Somel, M.
10.1101/247700 — evolutionary biology — Posted on 2018-01-15
1134 The mammalian decidual cell evolved from a cellular stress response
Erkenbrack, E. M.; Maziarz, J. D.; Griffith, O. W.; Liang, C.; Chavan, A. R.; Wagner, G. P.
10.1101/246397 — evolutionary biology — Posted on 2018-01-15
1137 Integration and analysis of CPTAC proteomics data in the context of cancer genomics in the cBioPortal
Wu, P.; Heins, Z. J.; Muller, J. T.; Abeshouse, A. A.; Sun, Y.; Schultz, N.; Fenyo, D.; Gao, J.
10.1101/247718 — cancer biology — Posted on 2018-01-15
1138 Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis
Halama, A.; Kulinski, M.; Dib, S. S.; Zaghlool, S. B.; Siveen, K. S.; Iskandarani, A.; Satheesh, N. J.; Bhagwat, A. M.; Uddin, S.; Kastenmueller, G.; Elemento, O.; Gross, S. S.; Suhre, K.
10.1101/230433 — cancer biology — Posted on 2018-01-15
1139 Fast and Flexible GPU Accelerated Binding Free Energy Calculations within the AMBER Molecular Dynamics Package
Mermelstein, D. J.; Lin, C.; Nelson, G.; Kretsch, R.; McCammon, J. A.; Walker, R. C.
10.1101/247692 — biophysics — Posted on 2018-01-15
1141 Data-driven characterization of molecular phenotypes across heterogenous sample collections
Mehtonen, J.; Polonen, P.; Hayrynen, S.; Lin, J.; Liuksiala, T.; Granberg, K.; Lohi, O.; Hautamaki, V.; Nykter, M.; Heinaniemi, M.
10.1101/248096 — bioinformatics — Posted on 2018-01-15
1142 Functional interaction of low-homology FRPs from different cyanobacteria with Synechocystis OCP
Slonimskiy, Y. B.; Maksimov, E. G.; Lukashev, E. P.; Moldenhauer, M.; Jeffries, C. M.; Svergun, D. I.; Friedrich, T.; Sluchanko, N. N.
10.1101/247882 — biochemistry — Posted on 2018-01-15
1145 FANCM-family branchpoint translocases remove co-transcriptional R-loops
Hodson, C.; O'Rourke, J. J.; van Twest, S.; Murphy, V. J.; Dunn, E.; Deans, A. J.
10.1101/248161 — biochemistry — Posted on 2018-01-15
1149 Epigenetic Drift of H3K27me3 in Aging Links Glycolysis to Healthy Longevity
Ma, Z.; Wang, H.; Cai, Y.; Wang, H.; Niu, K.; Wu, X.; Ma, H.; Yang, Y.; Tong, W.; Liu, F.; Liu, Z.; Zhang, Y.; Liu, R.; Zhu, Z.-J.; Liu, N.
10.1101/247726 — molecular biology — Posted on 2018-01-15
1150 Inherited BRCA1 epimutation as a novel cause of breast and ovarian cancer
Evans, D. G. R.; van Veen, E. M.; Byers, H. J.; Wallace, A. J.; Ellingford, J. M.; Beaman, G.; Santoyo-Lopez, J.; Aitman, T. J.; Eccles, D. M.; Lalloo, F. I.; Smith, M. J.; Newman, W. G.
10.1101/246934 — genetics — Posted on 2018-01-15
1151 Evolution of sexually-transferred steroids in Anopheles mosquitoes
Pondeville, E.; Puchot, N.; Lang, M.; Cherrier, F.; Schaffner, F.; Dauphin-Villemant, C.; Bischoff, E.; Bourgouin, C.
10.1101/248112 — evolutionary biology — Posted on 2018-01-15
1153 Combining global tree cover loss data with historical national forest-cover maps to look at six decades of deforestation and forest fragmentation in Madagascar
Vieilledent, G.; Grinand, C.; Rakotomalala, F. A.; Ranaivosoa, R.; Rakotoarijaona, J.-R.; Allnutt, T. F.; Achard, F.
10.1101/147827 — ecology — Posted on 2018-01-15
1155 Metabolic co-dependence drives the evolutionary ancient Hydra-Chlorella symbiosis
Hamada, M.; Schröder, K.; Bathia, J.; Kürn, U.; Fraune, S.; Khalturina, M.; Khalturin, K.; Shinzato, C.; Satoh, N.; Bosch, T. C. G.
10.1101/234757 — evolutionary biology — Posted on 2018-01-15
1156 GWAS on family history of Alzheimer’s disease
Marioni, R.; Harris, S. E.; McRae, A. F.; Zhang, Q.; Hagenaars, S. P.; Hill, W. D.; Davies, G.; Ritchie, C. W.; Gale, C.; Starr, J. M.; Goate, A.; Porteous, D. J.; Yang, J.; Evans, K. L.; Deary, I. J.; Wray, N. R.; Visscher, P. M.
10.1101/246223 — genetics — Posted on 2018-01-15
1159 Pervasive contingency and entrenchment in a billion years of Hsp90 evolution
Starr, T. N.; Flynn, J. M.; Mishra, P.; Bolon, D. N. A.; Thornton, J. W.
10.1101/189803 — evolutionary biology — Posted on 2018-01-14
1160 Development and worldwide use of a non-lethal and minimal population-level impact protocols for the isolation of chytrids from amphibians
Fisher, M. C.; Ghosh, P.; Shelton, J. M. G.; Bates, K.; Brookes, L.; Wierzbicki, C.; Rosa, G. M.; Farrer, R. A.; Aanensen, D. M.; Alvarado-Rybak, M.; Bataille, A.; Berger, L.; Boell, S.; Bosch, J.; Clare, F. C.; Courtois, E.; Crottini, A.; Cunningham, A. A.; Doherty-Bone, T. M.; Gebresenbet, F.; Gower, D. J.; Hoglund, J.; Jenkinson, T. S.; Kosch, T. A.; James, T. Y.; Lambertini, C.; Laurila, A.; Lin, C.-F.; Loyau, A.; Martel, A.; Meurling, S.; Miaud, C.; Minting, P.; Ndriantsoa, S.; Ribeiro, L. P.; Ribeiro, L.; Pasmans, F.; Rakotonanahary, T.; Rabemananjara, F. C. E.; Schmeller, D. S.; Schmidt
10.1101/246538 — ecology — Posted on 2018-01-14
1161 Mechanical strain can increase segment number in live chick embryos
Nelemans, B. K. A.; Schmitz, M.; Tahir, H.; Merks, R. M. H.; Smit, T. H.
10.1101/211623 — developmental biology — Posted on 2018-01-14
1162 Population-Averaged Atlas of the Macroscale Human Structural Connectome and Its Network Topology
Yeh, F.-C.; Panesar, S.; Fernandes, D.; Meola, A.; Yoshino, M.; Fernandez-Miranda, J. C.; Vettel, J.; Verstynen, T.
10.1101/136473 — neuroscience — Posted on 2018-01-14
1164 Ageing synaptic vesicles are inactivated by contamination with SNAP25
Truckenbrodt, S.; Viplav, A.; Jaehne, S.; Vogts, A.; Denker, A.; Wildhagen, H.; Fornasiero, E. F.; Rizzoli, S. O.
10.1101/172239 — neuroscience — Posted on 2018-01-14
1165 X10 Expansion Microscopy Enables 25 nm Resolution on Conventional Microscopes
Truckenbrodt, S.; Maidorn, M.; Crzan, D.; Wildhagen, H.; Kabatas, S.; Rizzoli, S. O.
10.1101/172130 — cell biology — Posted on 2018-01-14
1167 Microfluidic device for on-chip mixing and encapsulation of lysates
Chang, J.-C.; Swank, Z.; Keiser, O.; Maerkl, S. J.; Amstad, E.
10.1101/247627 — synthetic biology — Posted on 2018-01-14
1168 Aberrant calcium signaling in astrocytes inhibits neuronal excitability in a human Down syndrome stem cell model
Tian, L.; Or, G.; Wang, Y.; Shi, G.; Wang, Y.; Sun, J.; Papadopoulos, S.; Broussard, G.; Unger, E.; Deng, W.; Weick, J.; Bhattacharyya, A.; Chen, C.-Y.; Yu, G.; Looger, L.
10.1101/247585 — neuroscience — Posted on 2018-01-14
1170 Precise temporal regulation of alternative splicing during neural development
Weyn-Vanhentenryck, S. M.; Feng, H.; Ustianenko, D.; Duffie, R.; Yan, Q.; Jacko, M.; Martinez, J. C.; Goodwin, M.; Zhang, X.; Hengst, U.; Lomvardas, S.; Swanson, M. S.; Zhang, C.
10.1101/247601 — molecular biology — Posted on 2018-01-14
1171 ZFP36 RNA-binding proteins restrain T-cell activation and anti-viral immunity
Moore, M. J.; Blachere, N. E.; Fak, J. J.; Park, C. Y.; Sawicka, K.; Parveen, S.; Zucker-Scharff, I.; Moltedo, B.; Rudensky, A.; Darnell, R.
10.1101/247668 — molecular biology — Posted on 2018-01-14
1172 Beyond the ribosome: proteome-wide secretability studies using SECRiFY
Boone, M.; Ramasamy, P.; Maddelein, D.; Turan, D.; Martens, L.; Vandermarliere, E.; Vranken, W.; Callewaert, N.
10.1101/241349 — molecular biology — Posted on 2018-01-14
1175 Classification of Single Particles from Human Cell Extract Reveals Distinct Structures
Verbeke, E. J.; Mallam, A. L.; Drew, K.; Marcotte, E. M.; Taylor, D. W.
10.1101/247254 — biochemistry — Posted on 2018-01-14
1176 Computational haplotype recovery and long-read validation identifies novel isoforms of industrially relevant enzymes from natural microbial communities
Nicholls, S. M.; Aubrey, W.; Edwards, A.; de Grave, K.; Huws, S.; Schietgat, L.; Soares, A.; Creevey, C. J.; Clare, A.
10.1101/223404 — bioinformatics — Posted on 2018-01-13
1177 Non-monotonic spatial structure of inter-neuronal correlations in prefrontal microcircuits
Safavi, S.; Dwarakanath, A.; Kapoor, V.; Werner, J.; Hatsopoulos, N. G.; Logothetis, N. K.; Panagiotaropoulos, T. I.
10.1101/128249 — neuroscience — Posted on 2018-01-13
1184 Building a genome browser with GIVE
Cao, X.; Yan, Z.; Wu, Q.; Zheng, A.; Zhong, S.
10.1101/177832 — bioinformatics — Posted on 2018-01-13
1187 Novel metrics for quantifying bacterial genome composition skews
Joesch-Cohen, L. M.; Robinson, M.; Jabbari, N.; Lausted, C.; Glusman, G.
10.1101/176370 — genomics — Posted on 2018-01-12
1188 BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues
Zou, L. S.; Erdos, M. R.; Taylor, D. L.; Chines, P. S.; Varshney, A.; Genome Institute, T. M.; Parker, S. C. J.; Collins, F. S.; Didion, J. P.
10.1101/207506 — genomics — Posted on 2018-01-12
1191 A laboratory demand optimisation project in primary care
Bucholc, M.; O'Kane, M.; O'Hare, B.; Mullan, C.; Cavanagh, P.; Ashe, S.; Wong-Lin, K.
10.1101/247163 — pathology — Posted on 2018-01-12
1192 Focused learning promotes continual task performance in humans
Flesch, T.; Balaguer, J.; Dekker, R.; Nili, H.; Summerfield, C.
10.1101/247460 — neuroscience — Posted on 2018-01-12
1193 Structural and functional influences of urban and rural childhoods on the medial prefrontal cortex
Zhang, X.; Yan, H.; Yu, H.; Zhao, X.; Shah, S.; Dong, Z.; Yang, G.; Zhang, X.; Chen, Q.; Li, J.; Jiang, S.; Muse, T.; Liao, J.; Zhang, Y.; Yue, W.; Weinberger, D. R.; Zhang, D.; Tan, H. Y.
10.1101/246876 — neuroscience — Posted on 2018-01-12
1196 Genome-wide gene-environment analyses of depression and reported lifetime traumatic experiences in UK Biobank
Coleman, J. R. I.; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; UK Biobank Mental Health Consortium, ; Eley, T. C.; Breen, G.
10.1101/247353 — genomics — Posted on 2018-01-12
1197 Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels
Rees, E.; Carrera, N.; Morgan, J.; Hambridge, K.; Escott-Price, V.; Pocklington, A. J.; Richards, A. L.; Pardinas, A. F.; GROUP Investigators, ; McDonald, C.; Donohoe, G.; Morris, D. W.; Kenny, E.; Kelleher, E.; Gill, M.; Corvin, A.; Kirov, G.; Walters, J. T. R.; Holmans, P.; Owen, M. J.; O'Donovan, M. C.
10.1101/246850 — genetics — Posted on 2018-01-12
1199 Secondary contacts between European white oaks reveal genes underlying reproductive isolation
Leroy, T.; Rougemont, Q.; Bodenes, C.; Lalanne, C.; Belser, C.; Labadie, K.; Le Provost, G.; Aury, J.-M.; Kremer, A.; Plomion, C.
10.1101/246637 — evolutionary biology — Posted on 2018-01-12
1201 An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time
Razy-Krajka, F.; Gravez, B.; Kaplan, N.; Racioppi, C.; Wang, W.; Christiaen, L.
10.1101/138701 — developmental biology — Posted on 2018-01-12
1202 Cancer exosomes induce tumor neo-neurogenesis potentiating tumor growth
Madeo, M.; Colbert, P. L.; Vermeer, D. W.; Lucido, C. T.; Vichaya, E. G.; Grossberg, A. J.; Cain, J. T.; Muirhead, D.; Rickel, A. P.; Hong, Z.; Spanos, W. C.; Lee, J. H.; Dantzer, R.; Vermeer, P. D.
10.1101/247452 — cancer biology — Posted on 2018-01-12
1203 Genome analysis and data sharing informs timing of molecular events in pancreatic neuroendocrine tumour
Quevedo, R.; Spreafico, A.; Spreafico, A.; Bruce, J.; Danesh, A.; Giesler, A.; Hanna, Y.; Have, C.; Li, T.; Yang, S. Y. C.; Zhang, T.; Asa, S. L.; Haibe-Kains, B.; Kamel-Reid, S.; Krzyzanowska, M.; Smith, A.; Singh, S.; Siu, L. L.; Pugh, T. J.
10.1101/232850 — cancer biology — Posted on 2018-01-12
1204 Physical Principles of HIV Integration
Michieletto, D.; Lusic, M.; Marenduzzo, D.; Orlandini, E.
10.1101/247437 — biophysics — Posted on 2018-01-12
1208 A robust method for RNA extraction and purification from a single adult mouse tendon
Grinstein, M.; Dingwall, H. L.; Shah, R. R.; Capellini, T. D.; Galloway, J. L.
10.1101/247379 — molecular biology — Posted on 2018-01-12
1210 Type-2 CD8+ T lymphocytes responsive to PGD2 and LTE4 in severe eosinophilic asthma
Hilvering, B.; Hinks, T. S.; Stoger, L.; Marchi, E.; Salimi, M.; Shrimanker, R.; Liu, W.; Chen, W.; Luo, J.; Go, S.; Powell, T.; Cane, J.; Thulborn, S.; Kurioka, A.; Leng, T.; Matthews, J.; Connolly, C.; Borg, C.; Bafadhel, M.; Willberg, C.; Ramasamy, A.; Djukanovic, R.; Ogg, G.; Pavord, I. D.; Klenerman, P.; Xue, L.
10.1101/247171 — immunology — Posted on 2018-01-12
1211 RNA-seq transcript quantification from reduced-representation data in recount2
Fu, J.; Kammers, K.; Nellore, A.; Collado-Torres, L.; Leek, J. T.; Taub, M. A.
10.1101/247346 — genomics — Posted on 2018-01-12
1213 MITOMIX, an Algorithm to Reconstruct Population Admixture Histories Indicates Ancient European Ancestry of Modern Hungarians
Maroti, Z.; Torok, T.; Neparaczki, E.; Rasko, I.; Nagy, I.; Maroti, M.; Varga, T.; Bihari, P.; Boldogkoi, Z.; Tombacz, D.; Kalmar, T.
10.1101/247395 — genetics — Posted on 2018-01-12
1215 Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells
Murmann, A. E.; Gao, Q. Q.; Putzbach, W.; Patel, M.; Bartom, E. T.; Law, C.; Bridgeman, B.; Chen, S.; McMahon, K. M.; Thaxton, C. S.; Peter, M. E.
10.1101/247429 — cancer biology — Posted on 2018-01-12
1218 Targeted genome fragmentation with CRISPR/Cas9 improves hybridization capture, reduces PCR bias, and enables efficient high-accuracy sequencing of small targets
Nachmanson, D.; Lian, S.; Schmidt, E. K.; Hipp, M. J.; Baker, K. T.; Zhang, Y.; Tretiakova, M.; Loubet-Senear, K.; Kohrn, B. F.; Salk, J. J.; Kennedy, S. R.; Risques, R. A.
10.1101/207027 — genomics — Posted on 2018-01-12
1219 Comparison of village dog and wolf genomes highlights the pivotal role of the neural crest in dog domestication
Pendleton, A. L.; Shen, F.; Taravella, A. M.; Emery, S.; Veeramah, K. R.; Boyko, A. R.; Kidd, J. M.
10.1101/118794 — evolutionary biology — Posted on 2018-01-12
1221 Cause and consequences of genome duplication in haploid yeast populations
Fisher, K. J.; Buskirk, S. W.; Vignogna, R. C.; Marad, D. A.; Lang, G. I.
10.1101/247320 — evolutionary biology — Posted on 2018-01-12
1222 De novo origin of multicellularity in response to predation
Herron, M. D.; Borin, J. M.; Boswell, J. C.; Walker, J.; Knox, C. A.; Boyd, M.; Rosenzweig, F.; Ratcliff, W. C.
10.1101/247361 — evolutionary biology — Posted on 2018-01-12
1224 Wnt signalling drives context-dependent differentiation or proliferation in neuroblastoma
Szemes, M.; Greenhough, A.; Melegh, Z.; Malik, S.; Yuksel, A.; Catchpoole, D.; Gallacher, K.; Kollareddy, M.; Park, J. H.; Malik, K.
10.1101/236745 — cancer biology — Posted on 2018-01-12
1225 Engineering of a Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity
Mishra, S.; Chandler, S. A.; Williams, D.; Claxton, D. P.; Koteiche, H. A.; Stewart, P. L.; Benesch, J. L. P.; Mchaourab, H. S.
10.1101/247288 — biochemistry — Posted on 2018-01-12
1226 Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calmodulin (CaM) Effector in Mouse Brain
Evans, P. R.; Gerber, K. J.; Dammer, E. B.; Duong, D. M.; Goswami, D.; Lustberg, D. J.; Zou, J.; Yang, J. J.; Dudek, S. M.; Griffin, P. R.; Seyfried, N. T.; Hepler, J. R.
10.1101/247270 — biochemistry — Posted on 2018-01-12
1228 Intratumoral Heterogeneity of Tumor Infiltration of Glioblastoma Revealed by Joint Histogram Analysis of Diffusion Tensor Imaging
Li, C.; Wang, S.; Yan, J.-L.; Piper, R. J.; Liu, H.; Torheim, T.; Kim, H.; Zou, J.; Boonzaier, N. R.; Sinha, R.; Matys, T.; Markowetz, F.; Price, S. J.
10.1101/187450 — neuroscience — Posted on 2018-01-12
1230 Speech intelligibility predicted from neural entrainment of the speech envelope
Vanthornhout, J.; Decruy, L.; Wouters, J.; Simon, J. Z.; Francart, T.
10.1101/246660 — neuroscience — Posted on 2018-01-12
1231 Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity
Rounge, T. B.; Umu, S. U.; Keller, A.; Meese, E.; Ursin, G.; Tretli, S.; Lyle, R.; Langseth, H.
10.1101/247155 — molecular biology — Posted on 2018-01-12
1233 Targeted genome fragmentation with CRISPR/Cas9 improves hybridization capture, reduces PCR 3 bias, and enables efficient high-accuracy sequencing of small targets
Nachmanson, D.; Lian, S.; Schmidt, E. K.; Hipp, M. J.; Baker, K. T.; Zhang, Y.; Tretiakova, M.; Loubet-Senear, K.; Kohrn, B. F.; Salk, J. J.; Kennedy, S. R.; Risques, R. A.
10.1101/207027 — genomics — Posted on 2018-01-12
1234 Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
Lee, J. J.; Sanchez-Martinez, A.; Martinez Zarate, A.; Beninca, C.; Mayor, U.; Clague, M. J.; Whitworth, A. J.
10.1101/235077 — cell biology — Posted on 2018-01-12
1237 Mapping the human brain’s cortical-subcortical functional network organization
Spronk, M.; Ji, J. L.; Kulkarni, K.; Repovs, G.; Anticevic, A.; Cole, M. W.
10.1101/206292 — neuroscience — Posted on 2018-01-12
1239 A genomic island of Streptomyces coelicolor harbors the self-contained regulon of an ECF sigma factor
Kao, C. M.; Karoonuthaisiri, N.; Weaver, D.; Vroom, J. A.; Gai, S. A.; Ho, M.-L.; Patel, K. G.
10.1101/247056 — microbiology — Posted on 2018-01-12
1240 Host shifts result in parallel genetic changes when viruses evolve in closely related species
Longdon, B.; Day, J. P.; Alves, J. M.; Smith, S. C.; Houslay, T. M.; McGonigle, J. E.; Tagliaferri, L.; Jiggins, F. M.
10.1101/226175 — evolutionary biology — Posted on 2018-01-12
1245 Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration
Challis, R. C.; Kumar, S. R.; Chan, K. Y.; Challis, C.; Jang, M. J.; Rajendran, P. S.; Tompkins, J. D.; Shivkumar, K.; Deverman, B. E.; Gradinaru, V.
10.1101/246405 — neuroscience — Posted on 2018-01-11
1246 Speech intelligibility predicted from neural entrainment of the speech envelope
Vanthornhout, J.; Decruy, L.; Wouters, J.; Simon, J.; Francart, T.
10.1101/246660 — neuroscience — Posted on 2018-01-11
1250 HCMV glycoprotein B subunit vaccine efficacy was mediated by non-neutralizing antibody effector functions
Nelson, C. S.; Huffman, T.; Cisneros de la Rosa, E.; Xi, G.; Vandergrift, N.; Pass, R. F.; Pollara, J.; Permar, S. R.
10.1101/246884 — immunology — Posted on 2018-01-11
1251 Signatures of host specialization and a recent transposable element burst in the dynamic one-speed genome of the fungal barley powdery mildew pathogen
Frantzeskakis, L.; Kracher, B.; Kusch, S.; Yoshikawa-Maekawa, M.; Bauer, S.; Pesersen, C.; Spanu, P. D.; Maekawa, T.; Schulze-Lefert, P.; Panstruga, R.
10.1101/246280 — genomics — Posted on 2018-01-11
1254 High accuracy haplotype-derived allele frequencies from ultra-low coverage pool-seq samples
Tilk, S.; Bergland, A. O.; Goodman, A.; Schmidt, P.; Petrov, D.; Greenblum, S.
10.1101/244004 — evolutionary biology — Posted on 2018-01-11
1259 Automated map sharpening by maximization of detail and connectivity
Terwilliger, T. C.; Sobolev, O.; Afonine, P. V.; Adams, P. D.
10.1101/247049 — biochemistry — Posted on 2018-01-11
1264 A genomic island of Streptomyces coelicolor harbors the self-contained regulon of an ECF sigma factor
Kao, C. M.; Karoonuthaisiri, N.; Weaver, D.; Vroom, J. A.; Gai, S. A.; Ho, M.-L.; Patel, K. G.
10.1101/247056 — microbiology — Posted on 2018-01-11
1266 Climate change will lead to pronounced shifts in the diversity of soil microbial communities
Ladau, J.; Shi, Y.; Jing, X.; He, J.-S.; Chen, L.; Lin, X.; Fierer, N.; Gilbert, J. A.; Pollard, K. S.; Chu, H.
10.1101/180174 — ecology — Posted on 2018-01-11
1267 Larger legume plants host a greater diversity of symbiotic nitrogen-fixing bacteria
Dinnage, R.; Simonsen, A. K.; Cardillo, M.; Thrall, P. H.; Barrett, L. G.; Prober, S. M.
10.1101/246611 — ecology — Posted on 2018-01-11
1269 Larger legume plants host a greater diversity of symbiotic nitrogen-fixing bacteria
Dinnage, R.; Simonsen, A. K.; Cardillo, M.; Thrall, P. H.; Barrett, L. G.; Prober, S. M.
10.1101/246611 — ecology — Posted on 2018-01-11
1271 Transcription factor dynamics reveals a circadian code for fat cell differentiation
Bahrami-Nejad, Z.; Zhao, M. L.; Tholen, S.; Hunerdosse, D.; Tkach, K. M.; van Schie, S.; Chung, M.; Teruel, M. N.
10.1101/245332 — cell biology — Posted on 2018-01-11
1272 Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins
Allen, R. M.; Zhao, S.; Ramirez-Solano, M. A.; Michell, D. L.; Wang, Y.; Shyr, Y.; Sethupathy, P.; Linton, M. F.; Graf, G. A.; Sheng, Q.; Vickers, K. C.
10.1101/246900 — bioinformatics — Posted on 2018-01-11
1273 A genomic island of Streptomyces coelicolor harbors the self-contained regulon of an ECF sigma factor
Kao, C. M.; Karoonuthaisiri, N.; Weaver, D.; Vroom, J. A.; Gai, S. A.; Ho, M.-L.; Patel, K. G.
10.1101/247056 — microbiology — Posted on 2018-01-11
1274 Zebrafish type I collagen mutants faithfully recapitulate human type I collagenopathies
Gistelinck, C.; Kwon, R. Y.; Malfait, F.; Symoens, S.; Harris, M. P.; Henke, K.; Fisher, S.; Sips, P.; Guillemyn, B.; Beck, J. W.; Vermassen, P.; De Saffel, H.; Weis, M.; De Paepe, A.; Eyre, D. R.; Willaert, A.; Coucke, P.
10.1101/247023 — genetics — Posted on 2018-01-11
1276 Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis
Martinez-Abadias, N.; Mateu Estivill, R.; Sastre Tomas, J.; Motch Perrine, S.; Yoon, M.; Robert-Moreno, A.; Swoger, J.; Russo, L.; Kawasaki, K.; Richtsmeier, J.; Sharpe, J.
10.1101/246256 — developmental biology — Posted on 2018-01-11
1277 FoxN1-dependent thymic epithelial cells promote T-cell leukemia development
Ghezzo, M. N.; Fernandes, M. T.; Machado, R. S.; Pacheco-Leyva, I.; Araujo, M. A.; Kalathur, R. K. R.; Futschik, M. E.; Alves, N. L.; Rodrigues dos Santos, N.
10.1101/247015 — cancer biology — Posted on 2018-01-11
1280 Limitation of alignment-free tools in total RNA-seq quantification
Wu, D. C.; Yao, J.; Ho, K. S.; Lambowitz, A. M.; Wilke, C. O.
10.1101/246967 — bioinformatics — Posted on 2018-01-11
1282 Evidence for hyper-reductive redox in a subset of heart failure patients
Sairam, T.; Patel, A. N.; Subrahmanian, M.; Gopalan, R.; Pogwizd, S. M.; Ramalingam, S.; Ramalingam, S.; Namakkal-Soorappan, R.
10.1101/246413 — biochemistry — Posted on 2018-01-11
1284 Data-driven approaches improve Tau-PET biomarkers in Alzheimer’s disease
Vogel, J. W.; Mattsson, N.; Iturria-Medina, Y.; Strandberg, T. O.; Scholl, M.; Dansereau, C.; Villeneuve, S.; van der Flier, W. M.; Scheltens, P.; Bellec, P.; Evans, A. C.; Hansson, O.; Ossenkoppele, R.; the Alzheimer's Disease Neuroimaging Initiative, ; the Swedish BioFINDER study,
10.1101/244574 — neuroscience — Posted on 2018-01-11
1285 Open Source Brain: a collaborative resource for visualizing, analyzing, simulating and developing standardized models of neurons and circuits
Gleeson, P.; Cantarelli, M.; Marin, B.; Quintana, A.; Earnshaw, M.; Piasini, E.; Birgiolas, J.; Cannon, R. C.; Cayco-Gajic, N. A.; Crook, S.; Davison, A. P.; Dura-Bernal, S.; Ecker, A.; Hines, M. L.; Idili, G.; Larson, S.; Lytton, W. W.; Majumdar, A.; McDougal, R. A.; Sivagnanam, S.; Solinas, S.; Stanislovas, R.; van Albada, S. J.; Van Geit, W.; Silver, R. A.
10.1101/229484 — neuroscience — Posted on 2018-01-11
1286 Non-monotonic spatial structure of inter-neuronal correlations in prefrontal microcircuits
Safavi, S.; Dwarakanath, A.; Kapoor, V.; Werner, J.; Hatsopoulos, N. G.; Logothetis, N. K.; Panagiotaropoulos, T. I.
10.1101/128249 — neuroscience — Posted on 2018-01-11
1287 Direct Imaging of the circular chromosome of a live bacterium
Wu, F.; Japaridze, A.; Zheng, X.; Kerssemakers, J. W. J.; Dekker, C.
10.1101/246389 — microbiology — Posted on 2018-01-11
1288 Fine mapping chromatin contacts in capture Hi-C data
Eijsbouts, C.; Burren, O.; Newcombe, P.; Wallace, C.
10.1101/243642 — genomics — Posted on 2018-01-11
1289 Factor Structure and Heritability of Obsessive-Compulsive Traits in Children and Adolescents in the General Population
Burton, C. L.; Park, L. S.; Corfield, E. C.; Forget-Dubois, N.; Dupuis, A.; Sinopoli, V. M.; Shan, J.; Goodale, T.; Shaheen, S.-M.; Crosbie, J.; Schachar, R. J.; Arnold, P. D.
10.1101/246520 — genetics — Posted on 2018-01-11
1292 SpaRC: Scalable Sequence Clustering using Apache Spark
Shi, L.; Meng, X.; Tseng, E.; Mascagni, M.; Wang, Z.
10.1101/246496 — bioinformatics — Posted on 2018-01-11
1294 Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies different amino acid preferences between peptide-based substrates and inhibitors.
Deu, E.; de Vries, L. E.; Sanchez, M. I.; Groborz, K.; Kuppens, L.; Poreba, M.; Lehmann, C.; Yuan, F.; Arastu-Kapur, S.; Bogyo, M.; Drag, M.
10.1101/246124 — biochemistry — Posted on 2018-01-11
1295 In spoken word recognition the future predicts the past
Gwilliams, L.; Linzen, T.; Poeppel, D.; Marantz, A.
10.1101/150151 — neuroscience — Posted on 2018-01-11
1296 Population structure of the Brachypodium species complex and genome wide association of agronomic traits in response to climate.
Wilson, P. B.; Streich, J. C.; Murray, K. D.; Eichten, S. R.; Cheng, R.; Aitken, N. C.; Spokas, K.; Warthmann, N.; Accession Contributers, ; Borevitz, J. O.
10.1101/246074 — plant biology — Posted on 2018-01-11
1297 Development of subcortical volumes across adolescence in males and females: A multisample study of longitudinal changes
Herting, M. M.; Johnson, C.; Mills, K. L.; Vijayakumar, N.; Dennison, M.; Liu, C.; Goddings, A.-L.; Dahl, R. E.; Sowell, E. R.; Whittle, S.; Allen, N. B.; Tamnes, C. K.
10.1101/171389 — neuroscience — Posted on 2018-01-11
1298 Development and worldwide use of a non-lethal and minimal population-level impact protocols for the isolation of chytrids from amphibians
Fisher, M. C.; Ghosh, P.; Shelton, J. M. G.; Bates, K.; Brookes, L.; Wierzbicki, C.; Rosa, G. M.; Farrer, R. A.; Aanensen, D. M.; Alvarado-Rybak, M.; Bataille, A.; Berger, L.; Boell, S.; Bosch, J.; Clare, F.; Courtois, E.; Crottini, A.; Cunningham, A.; Doherty-Bone, T.; Gebresenbet, F.; Gower, D.; Hoglund, J.; Jenkinson, T.; Kosch, T.; James, T.; Lambertini, C.; Laurila, A.; Lin, C.-F.; Loyau, A.; Martel, A.; Meurling, S.; Miaud, C.; Minting, P.; Ndriantsoa, S.; Ribeiro, L.; Pasmans, F.; Rakotonanahary, T.; Rabemananjara, F.; Schmeller, D.; Schmidt, B.; Skerratt, L.; Smith, F.; Soto-Azat, C.;
10.1101/246538 — ecology — Posted on 2018-01-11
1299 E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo
Wang, X.; Zhang, K.; Ji, Z.; Cheng, C.; Zhao, H.; Sheng, Y.; Li, X.; Fan, L.; Dong, B.; Xue, W.; Gao, W.-Q.; Zhu, H.
10.1101/245449 — developmental biology — Posted on 2018-01-11
1307 Effective polyploidy causes phenotypic delay and influences bacterial evolvability
Sun, L.; Alexander, H. K.; Bogos, B.; Kiviet, D. J.; Ackermann, M.; Bonhoeffer, S.
10.1101/226654 — evolutionary biology — Posted on 2018-01-11
1309 miR-132 controls mouse pancreatic beta cell proliferation and survival through the Pten/Akt/Foxo3 signaling
MZIAUT, H.; Henniger, G.; Ganss, K.; Hempel, S.; Wolk, S.; McChord, J.; Chowdhury, K. C.; Knoch, K. P.; Weitz, J.; Grutzmann, R.; Pilarsky, C.; Solimena, M.; Kersting, S.
10.1101/233098 — cell biology — Posted on 2018-01-11
1310 Hi-TOM: a platform for high-throughput tracking of mutations induced by CRISPR/Cas systems
Liu, Q.; Wang, C.; Jiao, X.; Zhang, H.; Song, L.; Li, Y.; Gao, C.; Wang, K.
10.1101/235903 — bioinformatics — Posted on 2018-01-11
1312 Splice Expression Variation Analysis (SEVA) for Inter-tumor Heterogeneity of Gene Isoform Usage in Cancer
Afsari, B.; Guo, T.; Considine, M.; Florea, L.; Tsukamoto Kagohara, L.; Stein-O'Brien, G. L.; Kelley, D.; Flam, E.; Zambo, K. D.; Ha, P.; Geman, D.; Ochs, M. F.; Califano, J. A.; Gaykalova, D. A.; Favorov, A. V.; Fertig, E. J.
10.1101/091637 — genomics — Posted on 2018-01-11
1313 Identification of a novel, NF-κB nucleolar stress response pathway
Chen, J.; Lobb, I.; Morin, P.; Novo, S.; Simpson, J.; Kennerknecht, K.; Oakley, F.; Stark, L.
10.1101/100255 — cell biology — Posted on 2018-01-11
1314 Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites
Meerstein-Kessel, L.; van der Lee, R.; Stone, W.; Lanke, K.; Baker, D. A.; Alano, P.; Silvestrini, F.; Janse, C. J.; Khan, S. M.; van de Vegte-Bolmer, M.; Graumans, W.; Siebelink-Stoter, R.; Kooij, T. W.; Marti, M.; Drakeley, C.; Campo, J. J.; van Dam, T. J.; Sauerwein, R.; Bousema, T.; Huynen, M. A.
10.1101/199356 — microbiology — Posted on 2018-01-11
1315 Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa
Lourenco, J.; Monteiro, M. d. L.; Valdez, T.; Rodrigues, J. M.; Pybus, O.; Faria, N. R.
10.1101/198952 — epidemiology — Posted on 2018-01-11
1324 Whole brain comparative anatomy using connectivity blueprints
Mars, R. B.; Sotiropoulos, S. N.; Passingham, R. E.; Sallet, J.; Verhagen, L.; Krapitchev, A. A.; Sibson, N.; Jbabdi, S.
10.1101/245209 — neuroscience — Posted on 2018-01-10
1326 Thalamostriatal Interactions in Human Reversal Learning
Bell, T.; Langdon, A.; Lindner, M.; Lloyd, W.; Christakou, A.
10.1101/246371 — neuroscience — Posted on 2018-01-10
1327 SUCCESSIVE BLOODMEALS ENHANCE VIRUS DISSEMINATION WITHIN MOSQUITOES AND INCREASE TRANSMISSION POTENTIAL
Armstrong, P. M.; Ehrlich, H.; Bransfield, A.; Warren, J. L.; Pitzer, V. E.; Brackney, D. E.
10.1101/246306 — microbiology — Posted on 2018-01-10
1330 Count does not recover major events of gene flux in real biological data
Kapust, N.; Nelson-Sathi, S.; Schoenfeld, B.; Hazkani-Covo, E.; Bryant, D.; Lockhart, P. J.; Roettger, M.; Xavier, J. C.; Martin, W. F.
10.1101/246272 — evolutionary biology — Posted on 2018-01-10
1332 Oncogenic role of sFRP2 in P53-mutant osteosarcoma development via autocrine and paracrine mechanism
Kim, H. S.; Yoo, S.; Bernitz, J. M.; Yuan, Y.; Gomes, A. M.; Daniel, M. G.; Su, J.; Demicco, E. G.; Zhu, J.; Moore, K. A.; Lee, D.-F.; Lemischka, I. R.; Schaniel, C.
10.1101/246454 — cancer biology — Posted on 2018-01-10
1337 Using paired serology and surveillance data to quantify dengue transmission and control during a large outbreak in Fiji
Kucharski, A. J.; Kama, M.; Watson, C. H.; Aubry, M.; Funk, S.; Henderson, A. D.; Brady, O.; Vanhomwegen, J.; Manuguerra, J.-C.; Lau, C. L.; Edmunds, J.; Aaskov, J.; Nilles, E. J.; Cao-Lormeau, V.-M.; Hue, S.; Hibberd, M.
10.1101/246116 — epidemiology — Posted on 2018-01-10
1343 RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes
Bennett, A. H.; ODonohue, M. F.; Gundry, S. R.; Chan, A. T.; Widrick, J.; Draper, I.; Chakraborty, A.; Zhou, Y.; Zon, L. I.; Gleizes, P.-E.; Beggs, A. H.; Gupta, V. A.
10.1101/125484 — genetics — Posted on 2018-01-10
1347 Neuraminidase inhibitors - is it time to call it a day?
Parra-Rojas, C.; Nguyen, V. K.; Hernandez-Mejia, G.; Hernandez-Vargas, E.
10.1101/245175 — systems biology — Posted on 2018-01-10
1350 A master regulatory network restoring brain glutamate homeostasis is coordinately activated in stroke
Kobayashi, M.; Anderson, C.; Benakis, C.; Moore, M. J.; Mele, A.; Fak, J. J.; Park, C. Y.; Zhou, P.; Anrather, J.; Iadecola, C.; Darnell, R. B.
10.1101/245928 — neuroscience — Posted on 2018-01-10
1351 Causal Discovery of Feedback Networks with Functional Magnetic Resonance Imaging
Sanchez-Romero, R.; Ramsey, J. D.; Zhang, K.; Glymour, M. R. K.; Huang, B.; Glymour, C.
10.1101/245936 — neuroscience — Posted on 2018-01-10
1352 A scalable method to improve gray matter segmentation at ultra high field MRI
Gulban, O. F.; Schneider, M.; Marquardt, I.; Haast, R. A. M.; De Martino, F.
10.1101/245738 — neuroscience — Posted on 2018-01-10
1354 Sleep deprivation selectively up-regulates an amygdala-hypothalamic circuit involved in food reward
Rihm, J.; Menz, M. M.; Schultz, H.; Bruder, L.; Schilbach, L.; Schmid, S. M.; Peters, J.
10.1101/245845 — neuroscience — Posted on 2018-01-10
1356 Action-outcome knowledge dissociates from behavior in obsessive-compulsive disorder following contingency degradation
Vaghi, M. M.; Cardinal, R. N.; Apergis-Schoute, A. M.; Fineberg, N. A.; Sule, A.; Robbins, T. W.
10.1101/245944 — neuroscience — Posted on 2018-01-10
1357 BRD4 Deficiency Selectively Affects a Unique Developmental Subpopulation in Thymocytes
Gegonne, A.; Chen, Q.-R.; Dey, A.; Etzensperger, R.; Tai, X.; Singer, A.; Meerzaman, D.; Ozato, K.; Singer, D.
10.1101/245662 — immunology — Posted on 2018-01-10
1360 Genetic architecture of gene expression traits across diverse populations
Mogil, L. S.; Andaleon, A.; Badalamenti, A.; Dickinson, S. P.; Guo, X.; Rotter, J. I.; Johnson, W. C.; Im, H. K.; Liu, Y.; Wheeler, H. E.
10.1101/245761 — genomics — Posted on 2018-01-10
1362 Src-transformed cells hijack mitosis to extrude from the epithelium
Anton, K. A.; Kajita, M.; Narumi, R.; Fujita, Y.; Tada, M.
10.1101/246199 — cell biology — Posted on 2018-01-10
1367 ErbB4 deletion in noradrenergic neurons in the locus coeruleus induces mania-like behavior via elevated catecholamines
Cao, S.-X.; Zhang, Y.; Hu, X.-Y.; Hong, B.; Sun, P.; He, H.-Y.; Geng, H.-Y.; Bao, A.-M.; Duan, S.; Yang, J.-M.; Gao, T.-M.; Lian, H.; Li, X.-M.
10.1101/246215 — neuroscience — Posted on 2018-01-10
1370 Subgoal- and Goal-Related Prediction Errors in Medial Prefrontal Cortex
Ribas Fernandes, J. J. F.; Shahnazian, D.; Holroyd, C. B.; Botvinick, M. M.
10.1101/245829 — neuroscience — Posted on 2018-01-10
1371 The thermodynamic landscape of carbon redox biochemistry
Jinich, A.; Sanchez-Lengeling, B.; Ren, H.; Goldford, J. E.; Noor, E.; Sanders, J. N.; Segre, D.; Aspuru-Guzik, A.
10.1101/245811 — systems biology — Posted on 2018-01-10
1372 Exploring protein orthogonality in immune space: a case study with AAV and Cas9 orthologs
Moreno, A. M.; Palmer, N.; Aleman, F.; Chen, G.; Pla, A.; Chew, W. L.; Law, M.; Mali, P.
10.1101/245985 — synthetic biology — Posted on 2018-01-10
1373 Differential 3’ Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types
Jereb, S.; Hwang, H.-W.; Van Otterloo, E.; Govek, E.-E.; Fak, J. J.; Yuan, Y.; Hatten, M. E.; Darnell, R. B.
10.1101/245886 — neuroscience — Posted on 2018-01-10
1374 Functionally asymmetric motor neurons coordinate locomotion of Caenorhabditis elegans
Tolstenkov, O.; Van der Auwera, P.; Liewald, J. F.; Steuer Costa, W.; Bazhanova, O.; Gemeinhardt, T. M.; Bergs, A. C. F.; Gottschalk, A.
10.1101/244434 — neuroscience — Posted on 2018-01-10
1375 Data-mining of Antibiotic Resistance Genes Provides Insight into the Community Structure of Ocean Microbiome
Hao, S.; Yang, P.; Han, M.; Xu, J.; Yu, S.; Chen, C.; Chen, W.-H.; Zhang, H.; Ning, K.
10.1101/246033 — microbiology — Posted on 2018-01-10
1378 Hemodynamic forces tune the arrest, adhesion and extravasation of circulating tumor cells
Follain, G.; Osmani, N.; Azevedo, S.; Allio, G.; Mercier, L.; Karreman, M.; Solecki, G.; Garcia-Leon, M. J.; Lefebvre, O.; Fekonja, N.; Hille, C.; Chabannes, V.; Dolle, G.; Metivet, T.; Der Hovsepian, F.; Prudhomme, C.; Ruthensteiner, B.; Pichot, A.; Paul, N.; Carapito, R.; Bahram, S.; Kemmling, A.; Siemonsen, S.; Schneider, T.; Fiehler, J.; Glatzel, M.; Winkler, F.; Schwab, Y.; Pantel, K.; Harlepp, S.; Goetz, J. G.
10.1101/183046 — cancer biology — Posted on 2018-01-10
1379 TOGGLe, a flexible framework for easily building complex workflows and performing robust large-scale NGS analyses
Tranchant-Dubreuil, C.; Ravel, S.; Monat, C.; Sarah, G.; Diallo, A.; Helou, L.; Dereeper, A.; Tando, N.; Orjuela-Bouniol, J.; Sabot, F.
10.1101/245480 — bioinformatics — Posted on 2018-01-10
1384 Mid-Infrared Spectroscopy Study of Effects of Neonicotinoids on Forager Honey Bee (Apis mellifera) Fat Bodies and Their Connection to Colony Collapse Disorder
Feng, Y.; Luthra, A.; Ding, K.; Yang, Y.; Savage, J.; Wei, X.; Moeschter, R.; Ahuja, S.; Villegas, V.; Torbina, B.; Ahooja, A.; Ellis, T.; Boechler, A.-M.; Roberts, A.
10.1101/205112 — pharmacology and toxicology — Posted on 2018-01-09
1388 Adaptive potential of a drug-targeted viral protein as a function of environmental stress
Dai, L.; Du, Y.; Qi, H.; Huber, C. D.; Wu, N. C.; Wang, E.; Lloyd-Smith, J. O.; Sun, R.
10.1101/078428 — evolutionary biology — Posted on 2018-01-09
1391 Collicular circuits for flexible sensorimotor routing
Duan, C. A.; Pagan, M.; Piet, A. T.; Kopec, C. D.; Akrami, A.; Riordan, A. J.; Erlich, J. C.; Brody, C. D.
10.1101/245613 — neuroscience — Posted on 2018-01-09
1393 Heartfelt Face Perception via the Interoceptive Pathway - a MEG study
Kim, J.; Park, H.-d.; Kim, K. W.; Shin, D. W.; Lim, S.; Kwon, H.; Kim, M.-Y.; Kim, K.; Jeong, B.
10.1101/200980 — neuroscience — Posted on 2018-01-09
1395 Resolving the Full Spectrum of Human Genome Variation using Linked-Reads
Marks, P.; Garcia, S.; Martinez Barrio, A.; Belhocine, K.; Bernate, J.; Bharadwaj, R.; Bjornson, K.; Catalanotti, C.; Delaney, J.; Fehr, A.; Galvin, B.; Heaton, H.; Herschleb, J.; Hindson, C.; Holt, E.; Jabara, C. B.; Jett, S.; Keivanfar, N.; Kyriazopoulou-Panagiotopoulou, S.; Lek, M.; Lin, B.; Lowe, A.; Mahamdallie, S.; Maheshwari, S.; Makarewicz, T.; Marshall, J.; Meschi, F.; O'keefe, C.; Ordonez, H.; Patel, P.; Price, A.; Royall, A.; Ruark, E.; Seal, S.; Schnall-Levin, M.; Shah, P.; Williams, S.; Wu, I.; Wei Xu, A.; Rahman, N.; MacArthur, D.; Church, D. M.
10.1101/230946 — genomics — Posted on 2018-01-09
1396 Evaluation of gene-based family-based methods to detect novel genes associated with familial late onset Alzheimer disease
Fernandez, M. V.; Budde, J.; Del-Aguila, J.; Ibanez, L.; Deming, Y.; Harari, O.; Norton, J.; Morris, J. C.; Goate, A.; NIA-LOAD family study group, ; NCRAD, ; Cruchaga, C.
10.1101/242545 — genetics — Posted on 2018-01-09
1400 Is phylogenetic diversity a surrogate for functional diversity across clades and space?
Mazel, F.; Pennell, M.; Cadotte, M.; Diaz, S.; Dalla Riva, G.; Grenyer, R.; Leprieur, F.; Mooers, A.; Mouillot, D.; Tucker, C.; Pearse, W.
10.1101/243923 — ecology — Posted on 2018-01-09
1402 Observing the Cell in Its Native State: Imaging Subcellular Dynamics in Multicellular Organisms
Liu, T.-l.; Upadhyayula, S.; Milkie, D. E.; Singh, V.; Wang, K.; Swinburne, I. A.; Mosaliganti, K. R.; Collins, Z. M.; Hiscock, T. W.; Shea, J.; Kohrman, A. Q.; Medwig, T. N.; Dambournet, D.; Forster, R.; Cunniff, B.; Ruan, Y.; Yashiro, H.; Scholpp, S.; Meyerowitz, E. M.; Hockemeyer, D.; Drubin, D. G.; Martin, B. L.; Matus, D. Q.; Koyama, M.; Megason, S. G.; Kirchhausen, T.; Betzig, E.
10.1101/243352 — cell biology — Posted on 2018-01-09
1403 Network analysis of mass spectrometry imaging data from colorectal cancer identifies key metabolites common to metastatic development.
Inglese, P.; Strittmatter, N.; Doria, L.; Mroz, A.; Speller, A.; Poynter, L.; Dannhorn, A.; Kudo, H.; Mirnezami, R.; Goldin, R. D.; Nicholson, J. K.; Takats, Z.; Glen, R. C.
10.1101/230052 — cancer biology — Posted on 2018-01-09
1406 TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
Ji, L.; Jordan, W. T.; Shi, X.; Hu, L.; He, C.; Schmitz, R. J.
10.1101/151027 — plant biology — Posted on 2018-01-09
1407 Population Coding Of Conditional Probability Distributions In Dorsal Premotor Cortex
Glaser, J. I.; Perich, M. G.; Ramkumar, P.; Miller, L. E.; Kording, K. P.
10.1101/137026 — neuroscience — Posted on 2018-01-09
1411 Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers
Meier, B.; Volkova, N.; Hong, Y.; Schofield, P.; Campbell, P. J.; Gerstung, M.; Gartner, A.
10.1101/149153 — genomics — Posted on 2018-01-09
1412 Creating a universal SNP and small indel variant caller with deep neural networks
Poplin, R.; Newburger, D.; Dijamco, J.; Nguyen, N.; Loy, D.; Gross, S. S.; McLean, C. Y.; DePristo, M. A.
10.1101/092890 — genomics — Posted on 2018-01-09
1415 Critical transitions and the fragmenting of global forests
Saravia, L. A.; Doyle, S. R.; Bond-Lamberty, B.
10.1101/091751 — ecology — Posted on 2018-01-09
1416 A quantitative map of human Condensins provides new insights into mitotic chromosome architecture
Walther, N.; Hossain, M. J.; Politi, A. Z.; Koch, B.; Kueblbeck, M.; Oedegaard-Fougner, O.; Lampe, M.; Ellenberg, J.
10.1101/237834 — cell biology — Posted on 2018-01-09
1418 Heterochromatin drives organization of conventional and inverted nuclei
Falk, M.; Feodorova, Y.; Naumova, N.; Imakaev, M.; Lajoie, B. R.; Leonhardt, H.; Joffe, B.; Dekker, J.; Fudenberg, G.; Solovei, I.; Mirny, L.
10.1101/244038 — biophysics — Posted on 2018-01-09
1419 Identifying biomarkers of anti-cancer drug synergy using multi-task learning
Aben, N.; de Ruiter, J. R.; Bosdriesz, E.; Kim, Y.; Bounova, G.; Vis, D. J.; Wessels, L. F. A.; Michaut, M.
10.1101/243568 — bioinformatics — Posted on 2018-01-09
1420 Novel phosphorylation states of the yeast spindle pole body
Fong, K. K.; Zelter, A.; Graczyk, B.; Hoyt, J. M.; Riffle, M.; Johnson, R.; MacCoss, M. J.; Davis, T. N.
10.1101/245340 — biochemistry — Posted on 2018-01-09
1422 Expression of the Eight GABAA Receptor α Subunits in the Developing Zebrafish Central Nervous System
Monesson-Olson, B.; McClain, J. J.; Case, A. E.; Dorman, H. E.; Turkewitz, D. R.; Steiner, A. B.; Downes, G. B.
10.1101/244590 — neuroscience — Posted on 2018-01-09
1423 Whole body transcriptomes and new insights into the biology of the tick Ixodes ricinus
Charrier, P. N.; Couton, M.; Voordouw, M. J.; Rais, O.; Durand-Hermouet, A.; Hervet, C.; Plantard, O.; Rispe, C.
10.1101/244830 — genomics — Posted on 2018-01-09
1424 Targeted epigenomic changes to the maize methylome resulting from tissue culture
Han, Z.; Crisp, P. A.; Stelpflug, S.; Kaeppler, S.; Li, Q.; Springer, N. M.
10.1101/242081 — plant biology — Posted on 2018-01-09
1425 Manipulation of central amygdala neurotensin neurons alters alcohol consumption
Torruella-Suarez, M. L.; Vandenberg, J. R.; Tipton, G. J.; Luster, B. R.; Dange, K.; Patel, G. K.; McHenry, J. A.; Hardaway, J. A.; Kantak, P. A.; Crowley, N. A.; DiBerto, J. F.; Faccidomo, S. P.; Hodge, C. W.; Stuber, G. D.; McElligott, Z. A.
10.1101/245274 — neuroscience — Posted on 2018-01-09
1430 Genus-wide sequencing supports a two-locus model for sex-determination in Phoenix
Torres, M. F.; Mathew, L. S.; Ahmed, I.; Al-Azwani, I. K.; Krueger, R.; Rivera, D.; Mohamoud, Y. A.; Clark, A. G.; Suhre, K.; Malek, J. A.
10.1101/245514 — genomics — Posted on 2018-01-09
1431 Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Mahajan, A.; Taliun, D.; Thurner, M.; Robertson, N. R.; Torres, J. M.; Rayner, N. W.; Steinthorsdottir, V.; Scott, R. A.; Grarup, N.; Cook, J. P.; Schmidt, E. M.; Wuttke, M.; Sarnowski, C.; Mägi, R.; Nano, J.; Gieger, C.; Trompet, S.; Lecoeur, C.; Preuss, M.; Prins, B. P.; Guo, X.; Bielak, L. F.; DIAMANTE Consortium, ; Bennett, A. J.; Bork-Jensen, J.; Brummett, C. M.; Canouil, M.; Eckardt, K.-U.; Fischer, K.; Kardia, S. L.; Kronenberg, F.; Läll, K.; Liu, C.-T.; Locke, A. E.; Luan, J.; Ntalla, I.; Nylander, V.; Schönherr, S.; Schurmann, C.; Yengo, L.; Bottinger, E. P.;
10.1101/245506 — genomics — Posted on 2018-01-09
1432 Comparison of two African rice species through a new pan-genomic approach on massive data
Monat, C.; Tranchand, C.; Engelen, S.; Labadie, K.; Paradis, E.; Tando, N.; Sabot, F.
10.1101/245431 — genomics — Posted on 2018-01-09
1436 In silico design of ligand triggered RNA switches
Findeiss, S.; Hammer, S.; Wolfinger, M. T.; Kühnl, F.; Flamm, C.; Hofacker, I. L.
10.1101/245464 — bioinformatics — Posted on 2018-01-09
1437 Quantum chemistry reveals the thermodynamic principles of redoxbiochemistry
Jinich, A.; Flamholz, A.; Ren, H.; Kim, S.-J.; Sanchez-Lengeling, B.; Cotton, C. A. R.; Noor, E.; Aspuru-Guzik, A.; Bar-Even, A.
10.1101/245365 — biochemistry — Posted on 2018-01-09
1444 Transcription factor dynamics reveals a circadian code for fat cell differentiation
Bahrami-Nejad, Z.; Zhao, M. L.; Tholen, S.; Hunerdosse, D.; Tkach, K. M.; van Schie, S.; Chung, M.; Teruel, M. N.
10.1101/245332 — cell biology — Posted on 2018-01-09
1448 Neuron-specific cTag-CLIP reveals cell-specific diversity of functional RNA regulation in the brain
Saito, Y.; Yuan, Y.; Zucker-Scharff, I.; Fak, J. J.; Tajima, Y.; Licatalosi, D. D.; Darnell, R. B.
10.1101/244905 — neuroscience — Posted on 2018-01-08
1449 First spikes in visual cortex enable perceptual discrimination
Resulaj, A.; Ruediger, S.; Olsen, S. R.; Scanziani, M.
10.1101/245191 — neuroscience — Posted on 2018-01-08
1450 PET Brain imaging of α7-nAChR with ASEM Reproducibility, occupancy, receptor density, and changes in schizophrenia
Wong, D. F.; Kuwabara, H.; Horti, A. G.; Roberts, J.; Nandi, A.; Cascella, N.; Brasic, J. R.; Weerts, E.; Kitzmiller, K.; Phan, J. A.; Gapasin, L.; Sawa, A.; Valentine, H.; Wand, G.; George, N.; McDonald, M.; Kem, W.; Freedman, R.; Gjedde, A.
10.1101/245118 — neuroscience — Posted on 2018-01-08
1451 Comparative genomics of Pseudomonas syringae reveals convergent gene gain and loss associated with specialisation onto cherry (Prunus avium)
Hulin, M. T.; Armitage, A. D.; Vicente, J. G.; Holub, E. B.; Baxter, L.; Bates, H. P.; Mansfield, J. W.; Jackson, R. W.; Harrison, R. J.
10.1101/244715 — microbiology — Posted on 2018-01-08
1457 Varicella-zoster virus CNS vasculitis and RNA polymerase III gene mutation in identical twins
Carter-Timofte, M.; Hansen, A. F.; Mardahl, M.; Fribourg, S.; Rapaport, F.; Zhang, S.-Y.; Casanova, J.-L.; Paludan, S. R.; Christiansen, M.; Larsen, C. S.; Mogensen, T. H.
10.1101/244848 — immunology — Posted on 2018-01-08
1458 Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons
Yuan, Y.; Xie, S.; Darnell, J. C.; Darnell, A. J.; Saito, Y.; Phatnani, H.; Murphy, E. A.; Zhang, C.; Maniatis, T.; Darnell, R. B.
10.1101/237347 — neuroscience — Posted on 2018-01-08
1460 Modified penetrance of coding variants by cis-regulatory variation shapes human traits
Castel, S. E.; Cervera, A.; Mohammadi, P.; Aguet, F.; Reverter, F.; Wolman, A.; Guigo, R.; Iossifov, I.; Vasileva, A.; Lappalainen, T.
10.1101/190397 — genetics — Posted on 2018-01-08
1461 Integration of Brassinosteroid and Phytosulfokine Signalling Controls Vascular Cell Fate in the Arabidopsis Root
Holzwart, E.; Huerta, A. I.; Gloeckner, N.; Garnelo Gomez, B.; Ladwig, F.; Augustin, S.; Askani, J. C.; Schuerholz, A.-K.; Harter, K.; Wolf, S.
10.1101/244749 — plant biology — Posted on 2018-01-08
1463 Evaluation of gene-based family-based methods to detect novel genes associated with familial late onset Alzheimer disease
Cruchaga, C.; Feranndez, M. V.; Budde, J.; Del-Aguila, J.; Ibanez, L.; Deming, Y.; Harari, O.; Norton, J.; Morris, J. C.; Goate, A.
10.1101/242545 — genetics — Posted on 2018-01-08
1465 Deep Learning Based Proarrhythmia Analysis Using Field Potentials Recorded from Human Pluripotent Stem Cells Derived Cardiomyocytes
Golgooni, Z.; Mirsadeghi, S.; Soleymani Baghshah, M.; Ataee, P.; Baharvand, H.; Pahlavan, S.; Rabiee, H. R.
10.1101/244442 — bioinformatics — Posted on 2018-01-08
1467 A Portable Structural Analysis Library for Reaction Networks
Bedaso, Y. M.; Bergmann, F.; Choi, K. M.; Sauro, H. M.
10.1101/245068 — systems biology — Posted on 2018-01-08
1472 mTOR complex 1 pathway activation in severe keratoconus; the functional implications of GWAS identified loci.
Wisse, R. P.; Kuiper, J. J.; de Veij Mestdagh, G. M.; Wichers, C. G.; Hiddingh, S.; Vazirpanah, N.; Imhof, S. M.; Radstake, T. R.; Broen, J. C.
10.1101/244897 — molecular biology — Posted on 2018-01-08
1474 Oscillating bacterial expression states generate herd immunity to viral infection
Turkington, C. J. R.; Morozov, A.; Clokie, M. R. J.; Bayliss, C. D.
10.1101/244814 — microbiology — Posted on 2018-01-08
1476 The smallest intestine (TSI) - a low volume in vitro model of the small intestine with increased throughput
Cieplak, T.; Wiese, M.; Nielsen, S.; Van de Wiele, T.; van den Berg, F.; Nielsen, D. S.
10.1101/244764 — microbiology — Posted on 2018-01-08
1477 Validation of a 14-drug microtitre plate that includes delamanid and bedaquiline for susceptibility testing of M. tuberculosis
Rancoita, P. M.; Cugnata, F.; Gibertoni Cruz, A. L.; Borroni, E.; Hoosdally, S. J.; Walker, T. M.; Grazian, C.; Davies, T. J.; Peto, T. E.; Crook, D. W.; Fowler, P. W.; Cirillo, D. M.; the CRyPTIC Consortium,
10.1101/244731 — microbiology — Posted on 2018-01-08
1479 Genotype Imputation Performance of Three Reference Panels Using African Ancestry Individuals
Vergara, C.; Parker, M. M.; Franco, L.; Cho, M. H.; Valencia-Duarte, A. V.; Beaty, T. H.; Duggal, P.
10.1101/245035 — genetics — Posted on 2018-01-08
1480 Transcriptomic response to host and non-host plants during oviposition in two closely related moth species
Orsucci, M.; Audiot, P.; Nidelet, S.; Dorkeld, F.; Pommier, A.; Vabre, M.; Severac, D.; Rohmer, M.; Gschloessl, B.; Streiff, R.
10.1101/244806 — evolutionary biology — Posted on 2018-01-08
1481 Phylogenomics and barcoding of Panax: toward the identification of ginseng species
Manzanilla, V.; Kool, A.; Nguyen Nhat, L.; Nong Van, H.; Hien, L. T. T.; de Boer, H.
10.1101/244780 — evolutionary biology — Posted on 2018-01-08
1482 Heterogeneous susceptibility to rotavirus infection and gastroenteritis in two birth cohort studies: parameter estimation and epidemiological implications
Lewnard, J. A.; Lopman, B. A.; Parashar, U. D.; Bennett, A.; Bar-Zeev, N.; Cunliffe, N. A.; Samuel, P.; Guerrero, M. L.; Ruiz-Palacios, G. M.; Kang, G.; Pitzer, V. E.
10.1101/242172 — epidemiology — Posted on 2018-01-08
1483 Malaria during pregnancy and newborns outcome in an unstable transmission area in Brazil: a population-based record linkage study
Dombrowski, J. G.; Souza, R. M.; Silva, N. R. M.; Barateiro, A.; Epiphanio, S.; Goncalves, L. A.; Marinho, C. R. F.
10.1101/244178 — epidemiology — Posted on 2018-01-08
1485 An ancient integration in a plant NLR is maintained as a trans-species polymorphism
Brabham, H. J.; Hernandez-Pinzon, I.; Holden, S.; Lorang, J.; Moscou, M. J.
10.1101/239541 — plant biology — Posted on 2018-01-08
1488 Radial glial lineage progression and differential intermediate progenitor amplification underlie striatal compartments and circuit organization
Kelly, S. M.; He, M.; Lee, J.; Kim, Y.; Gibb, L. G.; Wu, P.; Matho, K.; Osten, P.; Graybiel, A. M.; Huang, Z. J.
10.1101/244327 — neuroscience — Posted on 2018-01-08
1490 Automated detection of Mycobacterial growth on 96-well plates for rapid and accurate Tuberculosis drug susceptibility testing
Fowler, P. W.; Gibertoni Cruz, A. L.; Hoosdally, S. J.; Jarrett, L.; Borroni, E.; Chiacchiaretta, M.; Rathod, P.; Walker, T. M.; Robinson, E.; Peto, T. E.; Cirillo, D. M.; Smith, E. G.; Crook, D. W.
10.1101/229427 — microbiology — Posted on 2018-01-08
1491 Sequential regulatory activity prediction across chromosomes with convolutional neural networks
Kelley, D. R.; Reshef, Y. A.; Belanger, D.; McLean, C.; Snoek, J.; Bileschi, M.
10.1101/161851 — genomics — Posted on 2018-01-08
1492 Non-B DNA affects polymerization speed and error rate in sequencers and living cells
Guiblet, W. M. F.; Cremona, M. A.; Cechova, M.; Harris, R. S.; Kejnovska, I.; Kejnovsky, E.; Eckert, K.; Chiaromonte, F.; Makova, K. D.
10.1101/237461 — genomics — Posted on 2018-01-08
1496 Reducing Pyrrolysine tRNA Copy Number Improves Live Cell Imaging of Bioorthogonally Labeled Proteins
Aloush, N.; Schvartz, T.; König, A.; Cohen, S.; Tam, B.; Akabayov, B.; Nachmias, D.; Ben-David, O.; Elia, N.; Arbely, E.
10.1101/161984 — synthetic biology — Posted on 2018-01-08
1497 TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
Ji, L.; Jordan, W. T.; Shi, X.; Hu, L.; He, C.; Schmitz, R. J.
10.1101/151027 — plant biology — Posted on 2018-01-08
1499 Expression of the Eight GABAA Receptor α Subunits in the Developing Zebrafish Central Nervous System
Monesson-Olson, B.; McClain, J. J.; Case, A. E.; Dorman, H. E.; Turkewitz, D. R.; Steiner, A. B.; Downes, G.
10.1101/244590 — neuroscience — Posted on 2018-01-08
1502 The BAP1 deubiquitinase complex is a general transcriptional co-activator
Campagne, A.; Zielinski, D.; Michaud, A.; Le Corre, S.; Dingli, F.; Chen, H.; Vassilev, I.; Lee, M.-K.; Servant, N.; Loew, D.; Pasmant, E.; Postel-Vinay, S.; Wassef, M.; Margueron, R.
10.1101/244152 — genomics — Posted on 2018-01-08
1503 Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use
Pasman, J. A.; Verweij, K. J. H.; Gerring, Z.; Stringer, S.; Sanchez-Roige, S.; Treur, J. L.; Abdellaoui, A.; Nivard, M. G.; Baselmans, B. M. L.; Ong, J.-S.; Ip, H. F.; van der Zee, M. D.; Bartels, M.; Day, F. R.; Fontanillas, P.; Elson, S. L.; the 23andMe Research Team, ; de Wit, H.; Davis, L. K.; MacKillop, J.; International Cannabis Consortium, ; Derringer, J. L.; Branje, S. J. T.; Hartman, C. A.; Heath, A. C.; van Lier, P. A. C.; Madden, P. A. F.; Magi, R.; Meeus, W.; Montgomery, G. W.; Oldehinkel, A. J.; Pausova, Z.; Ramos-Quiroga, J. A.; Paus, T.; Ribases, M.; Kaprio, J.; Boks, M. P. M
10.1101/234294 — genetics — Posted on 2018-01-08
1504 A compromised gsdf signaling leads to gamatogenesis confusion and subfertility in medaka
Guan, G.; Xu, S.; Guo, A.; Zhao, X.; Zhang, Y.; Sun, K.; Kang, Y.; Chang, Y.; Wu, X.; Chen, L.
10.1101/238436 — evolutionary biology — Posted on 2018-01-08
1507 No evidence that more physically attractive women have higher estradiol or progesterone
Jones, B. C.; Hahn, A. C.; Fisher, C. I.; Wang, H.; Kandrik, M.; Lao, J.; Han, C.; Lee, A. J.; Holzleitner, I. J.; DeBruine, L. M.
10.1101/136515 — animal behavior and cognition — Posted on 2018-01-08
1509 Critical transitions and the fragmenting of global forests
Saravia, L. A.; Doyle, S. R.; Bond-Lamberty, B.
10.1101/091751 — ecology — Posted on 2018-01-08
1510 Agricultural Pollution Risks Influence Microbial Ecology in Honghu Lake
Han, M.; Dsouza, M.; Zhou, C.; Li, H.; Zhang, J.; Chen, C.; Yao, Q.; Zhong, C.; Zhou, H.; Gilbert, J. A.; Wang, Z.; Ning, K.
10.1101/244657 — microbiology — Posted on 2018-01-08
1511 HOTAIR primes the Ewing sarcoma family of tumors for tumorigenesis via epigenetic dysregulation involving LSD1
Siddiqui, H.; Selich-Anderson, J.; Felgenhauer, J.; Fitch, J.; Nadella, V.; Taslim, C.; Tomino, L.; Theisen, E.; Otsuru, S.; Horwitz, E.; Lessnick, S. L.; White, P.; Shah, N.
10.1101/244558 — cancer biology — Posted on 2018-01-08
1515 Genome-wide Meta-analysis of 158,000 Individuals of European Ancestry Identifies Three Loci Associated with Chronic Back Pain
Suri, P.; Palmer, M. R.; Tsepilov, Y. A.; Freidin, M. B.; Boer, C. G.; Yau, M.; Evans, D. S.; Gelemanovic, A.; Bartz, T. M.; Nethander, M.; Arbeeva, L.; Karssen, L.; Neogi, T.; Campbell, A.; Mellstrom, D.; Ohlsson, C.; Marshall, L. M.; Orwoll, E.; Uitterlinden, A.; Lauc, G.; Psaty, B. M.; Karlsson, M. K.; Lane, N. E.; Jarvik, G. P.; Polasek, O.; Hochberg, M.; Jordan, J. M.; Van Meurs, J. B.; Jackson, R.; Nielson, C. M.; Mitchell, B. D.; Smith, B. H.; Hayward, C.; Smith, N.; Aulchenko, Y. S.; Williams, F. M.
10.1101/244483 — genomics — Posted on 2018-01-08
1516 Building superfast muscles: insights from molecular parallelism in fast-twitch muscle proteins in echolocating mammals
Lee, J.-H.; Lewis, K. M.; Moural, T. W.; Kirilenko, B.; Borgonovo, B.; Prange, G.; Koessl, M.; Huggenberger, S.; Kang, C.; Hiller, M.
10.1101/244566 — evolutionary biology — Posted on 2018-01-08
1517 Molecular phylogeny of Odontosyllis (Annelida, Syllidae): A recent and rapid radiation of marine bioluminescent worms.
Verdes, A.; Alvarez-Campos, P.; Nygren, A.; San Martin, G.; Rouse, G.; Deheyn, D. D.; Gruber, D. F.; Holford, M.
10.1101/241570 — evolutionary biology — Posted on 2018-01-08
1518 Fidaxomicin jams M. tuberculosis RNA polymerase motions needed for initiation via RbpA contacts
Boyaci, H.; Chen, J.; Lilic, M.; Palka, M.; Mooney, R. A.; Landick, R.; Darst, S. A.; Campbell, E. A.
10.1101/244533 — biophysics — Posted on 2018-01-08
1519 Role of dynamic cooperativity in the mechanism of hexameric M17 aminopeptidases.
Drinkwater, N.; Yang, W.; Riley, B. T.; Kannan Sivaraman, K.; Kass, I.; Buckle, A. M.; McGowan, S.
10.1101/244665 — biochemistry — Posted on 2018-01-08
1520 Observing the Cell in Its Native State: Imaging Subcellular Dynamics in Multicellular Organisms
Liu, T.-l.; Upadhyayula, S.; Milkie, D. E.; Singh, V.; Wang, K.; Swinburne, I. A.; Mosaliganti, K. R.; Collin, Z. M.; Hiscock, T. W.; Shea, J.; Kohrman, A. Q.; Medwig, T. N.; Dambournet, D.; Forster, R.; Cunniff, B.; Ruan, Y.; Yashiro, H.; Scholpp, S.; Meyerowitz, E. M.; Hockemeyer, D.; Drubin, D. G.; Martin, B. L.; Matus, D. Q.; Koyama, M.; Megason, S. G.; Kirchhausen, T.; Betzig, E.
10.1101/243352 — cell biology — Posted on 2018-01-08
1527 The Developing Human Connectome Project: a Minimal Processing Pipeline for Neonatal Cortical Surface Reconstruction
Makropoulos, A.; Robinson, E. C.; Schuh, A.; Wright, R.; Fitzgibbon, S.; Bozek, J.; Counsell, S. J.; Steinweg, J.; Passerat-Palmbach, J.; Lenz, G.; Mortari, F.; Tenev, T.; Duff, E. P.; Bastiani, M.; Cordero-Grande, L.; Hughes, E.; Tusor, N.; Tournier, J.-D.; Hutter, J.; Price, A. N.; Murgasova, M.; Kelly, C.; Rutherford, M. A.; Smith, S. M.; Edwards, A. D.; Hajnal, J. V.; Jenkinson, M.; Rueckert, D.
10.1101/125526 — neuroscience — Posted on 2018-01-07
1529 Characterization of strawberry (Fragaria vesca) sequence genome
Ao, L.; Lide, C.; Zhongjie, L.; Mengjie, C.; Lingfei, S.; Haifeng, J.; Jinggui, F.
10.1101/244418 — bioinformatics — Posted on 2018-01-07
1530 Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons
Yuan, Y.; Xie, S.; Darnell, J. C.; Darnell, A. J.; Saito, Y.; Phatnani, H.; Murphy, E.; Zhang, C.; Maniatis, T.; Darnell, R.
10.1101/237347 — neuroscience — Posted on 2018-01-07
1536 Genome-wide enhancer - gene regulatory maps in two vertebrate genomes
Clement, Y.; Torbey, P.; Gilardi-Hebenstreit, P.; Roest Crollius, H.
10.1101/244475 — genomics — Posted on 2018-01-07
1540 Control and the Analysis of Cancer Growth Models
Tannenbaum, A. R.; Georgiou, T.; Deasy, J.; Norton, L.
10.1101/244301 — cancer biology — Posted on 2018-01-07
1544 Rapid sensing of L-leucine by human and murine hypothalamic neurons: neurochemical and mechanistic insights
Heeley, N.; Kirwan, P.; Darwish, T.; Arnaud, M.; Evans, M.; Merkle, F.; Reimann, F.; Gribble, F.; Blouet, C.
10.1101/244111 — neuroscience — Posted on 2018-01-07
1545 Inferring Species Trees Using Integrative Models of Species Evolution
Ogilvie, H. A.; Vaughan, T. G.; Matzke, N. J.; Slater, G. J.; Stadler, T.; Welch, D.; Drummond, A. J.
10.1101/242875 — evolutionary biology — Posted on 2018-01-07
1547 Rapid Identification and Validation of Novel Rheumatoid Arthritis Drug Treatments using an Integrative Bioinformatics Platform
Daugherty, A. C.; Farrington, C.; Hakin, I.; Mujahid, S.; Noblin, E. S.; Radin, A. M.; Chua, M.-S.; Rabe, M.; Fernald, G.; Ford, D.; Sirota, M.; Schaevitz, L.; Radin, A. A.
10.1101/243998 — bioinformatics — Posted on 2018-01-07
1551 A computational framework for converting high-throughput DNA sequencing data into neural circuit connectivity.
Oyibo, H.; Cao, C.; Ferrante, D. D.; Zhan, H.; Koulakov, A. A.; Enquist, L.; Dubnau, J.; Zador, A.
10.1101/244079 — neuroscience — Posted on 2018-01-07
1552 The BAP1 deubiquitinase complex is a general transcriptional co-activator
Campagne, A.; Zielinski, D.; Michaud, A.; Le Corre, S.; Dingli, F.; Chen, H.; Vassilev, I.; Lee, M.-K.; Servant, N.; Loew, D.; Pasmant, E.; Postel-Vinay, S.; Wassef, M.; Margueron, R.
10.1101/244152 — genomics — Posted on 2018-01-07
1556 The evolutionary history of Nebraska deer mice: local adaptation in the face of strong gene flow
Pfeifer, S. P.; Laurent, S.; Sousa, V. C.; Linnen, C. R.; Foll, M.; Excoffier, L.; Hoekstra, H. E.; Jensen, J. D.
10.1101/152694 — evolutionary biology — Posted on 2018-01-06
1557 Targeting histone deacetylase activity to arrest cell growth and promote neural differentiation in Ewing sarcoma
Souza, B. K.; Lopez, P. L. d. C.; Menegotto, P. R.; Vieira, I. A.; Kersting, N.; Abujamra, A. L.; Brunetto, A. T.; Brunetto, A. L.; Gregianin, L.; de Farias, C. B.; Thiele, C. J.; Roesler, R.
10.1101/191700 — cancer biology — Posted on 2018-01-06
1561 Dynamin-2 facilitates Atg9 recycling from nascent autophagosomes
Martorell Riera, A.; Iriondo Martinez, C.; Itskanov, S.; Steffen, J.; Roach, B.; Koehler, C. M.; Van der Bliek, A. M.
10.1101/241901 — cell biology — Posted on 2018-01-06
1563 A systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria
Belliveau, N. M.; Barnes, S. L.; Ireland, W. T.; Jones, D. L.; Sweredoski, M. J.; Moradian, A.; Hess, S.; Kinney, J. B.; Phillips, R.
10.1101/239335 — biophysics — Posted on 2018-01-06
1566 Rapid, noninvasive, and unsupervised detection of sleep/wake using piezoelectric monitoring for pharmacological studies in narcoleptic mice
Black, S. W.; Sun, J. D.; Laihsu, A.; Kimura, N.; Santiago, P.; Donohue, K. D.; O'Hara, B. F.; Bersot, R.; Humphries, P. S.
10.1101/226522 — neuroscience — Posted on 2018-01-05
1569 BOFdat: generating biomass objective function stoichiometric coefficients from experimental data
Lachance, J.-C.; Monk, J. M.; Lloyd, C. J.; Seif, Y.; Palsson, B. O.; Rodrigue, S.; Feist, A. M.; King, Z. A.; Jacques, P.-E.
10.1101/243881 — systems biology — Posted on 2018-01-05
1576 The Homeostatic Logic of Reward
Morville, T.; Friston, K.; Burdakov, D.; Siebner, H. R.; Hulme, O. J.
10.1101/242974 — neuroscience — Posted on 2018-01-05
1580 An empirical, 21st century evaluation of phrenology
Parker Jones, O.; Alfaro-Almagro, F.; Jbabdi, S.
10.1101/243089 — neuroscience — Posted on 2018-01-05
1581 Optogenetic dissection of descending behavioral control in Drosophila
Cande, J.; Berman, G. J.; Namiki, S.; Qiu, J.; Korff, W.; Card, G.; Shaevitz, J. W.; Stern, D. L.
10.1101/230128 — neuroscience — Posted on 2018-01-05
1583 Cross-feeding modulates antibiotic tolerance in bacterial communities
Adamowicz, E. M.; Hunter, R. C.; Flynn, J.; Harcombe, W. R.
10.1101/243949 — microbiology — Posted on 2018-01-05
1584 Fe oxidation by a fused cytochrome-porin common to diverse Fe-oxidizing bacteria
Chan, C.; McAllister, S. M.; Garber, A.; Hallahan, B. J.; Rozovsky, S.
10.1101/228056 — microbiology — Posted on 2018-01-05
1585 Listeria monocytogenes InlP interacts with afadin and facilitates basement membrane crossing
Faralla, C.; Bastounis, E. E.; Ortega, F. E.; Light, S. H.; Rizzuto, G.; Nocadello, S.; Anderson, W. F.; Robbins, J. R.; Theriot, J. A.; Bakardjiev, A. I.
10.1101/242222 — microbiology — Posted on 2018-01-05
1586 Transcriptome assembly and annotation of johnsongrass (Sorghum halepense) rhizomes identifies candidate rhizome specific genes
Ryder, N.; Dorn, K. M.; Huitsing, M.; Adams, M.; Ploegstra, J.; DeHaan, L.; Larson, S.; Tintle, N.
10.1101/243956 — genomics — Posted on 2018-01-05
1590 Is phylogenetic diversity a surrogate for functional diversity across clades and space?
Mazel, F.; Pennell, M.; Cadotte, M.; Diaz, S.; Dalla Riva, G.; Grenyer, R.; Leprieur, F.; Mooers, A.; Mouillot, D.; Tucker, C.; Pearse, W.
10.1101/243923 — ecology — Posted on 2018-01-05
1592 Multicenter validation of a sepsis prediction algorithm using only vital sign data in the emergency department, general ward and ICU
Mao, Q.; Jay, M.; Hoffman, J.; Calvert, J.; Barton, C.; Shimabukuro, D.; Shieh, L.; Chettipally, U.; Fletcher, G.; Kerem, Y.; Zhou, Y.; Das, R.
10.1101/243964 — bioinformatics — Posted on 2018-01-05
1596 Comparative Network Reconstruction using Mixed Integer Programming
Bosdriesz, E.; Prahallad, A.; Klinger, B.; Sieber, A.; Bosma, A.; Bernards, R.; Bluthgen, N.; Wessels, L. F.
10.1101/243709 — systems biology — Posted on 2018-01-05
1598 Otx2 signals from the choroid plexus to regulate adult neurogenesis
Planques, A.; Oliveira Moreira, V.; Dubreuil, C.; Prochiantz, A.; Di Nardo, A. A.
10.1101/243659 — neuroscience — Posted on 2018-01-05
1599 Microbiota Accessible Carbohydrates Facilitate Clearance of Clostridium difficile
Hryckowian, A. J.; Van Treuren, W.; Smits, S. A.; Davis, N. M.; Gardner, J. O.; Bouley, D. M.; Sonnenburg, J. L.
10.1101/243253 — microbiology — Posted on 2018-01-05
1600 Fine mapping chromatin contacts in capture Hi-C data
Eijsbouts, C.; Burren, O.; Newcombe, P.; Wallace, C.
10.1101/243642 — genomics — Posted on 2018-01-05
1601 Efficacy and dynamics of self-targeting CRISPR/Cas constructs for gene editing in the retina.
Li, F.; Hung, S. S.; Wang, J.-H.; Chrysostomou, V.; Wong, V. H.; Bender, J. A.; Tu, L.; Pebay, A.; King, A. E.; Cook, A. L.; Wong, R. C.; Bui, B. V.; Hewitt, A.; Liu, G.-S.
10.1101/243683 — genetics — Posted on 2018-01-05
1605 Building online genomics applications using BioPyramid
Stephenson, L.; Wakeham, Y.; Seidenman, N.; Choi, J.
10.1101/243378 — bioinformatics — Posted on 2018-01-05
1608 Cytokinin activity of N6-benzyladenine derivatives assayed by interaction with the receptors in planta, in vitro, and in silico
Savelieva, E. M.; Oslovsky, V. E.; Karlov, D. S.; Kurochkin, N. N.; Getman, I. A.; Lomin, S. N.; Sidorov, G. V.; Mikhailov, S. N.; Osolodkin, D. I.; Romanov, G. A.
10.1101/241281 — plant biology — Posted on 2018-01-05
1609 Coordinated activity of sleep and arousal neurons for stabilizing sleep/wake states in Drosophila
Ni, J. D.; Ogunmowo, T. H.; Hackbart, H.; Elsheikh, A.; Gurav, A. S.; Verdegaal, A. A.; Montell, C.
10.1101/243444 — neuroscience — Posted on 2018-01-05
1613 Efficient neural decoding of self-location with a deep recurrent network
Tampuu, A.; Matiisen, T.; Olafsdottir, H. F.; Barry, C.; Vicente, R.
10.1101/242867 — neuroscience — Posted on 2018-01-05
1615 Designed hybrids facilitate efficient generation of high-resolution linkage maps
Yoshitake, K.; Igarashi, Y.; Mizukoshi, M.; Kinoshita, S.; Mitsuyama, S.; Suzuki, Y.; Saito, K.; Watabe, S.; Asakawa, S.
10.1101/243451 — genomics — Posted on 2018-01-05
1616 Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent Giant Cell Arteritis
De Smit, E.; Lukowski, S. W.; Anderson, L.; Senabouth, A.; Dauyey, K.; Song, S.; Wyse, B.; Wheeler, L.; Chen, C. Y.; Cao, K.; Yuen, A. W. T.; Shuey, N.; Clarke, L.; Sanchez, I. L.; Hung, S. S.; Pebay, A.; Mackey, D. A.; Brown, M. A.; Hewitt, A.; Powell, J. E.
10.1101/243493 — genomics — Posted on 2018-01-05
1617 Protein-coding variation and introgression of regulatory alleles drive plumage pattern diversity in the rock pigeon
Vickrey, A.; Bruders, R.; Kronenberg, Z.; Mackey, E.; Bohlender, R. J.; Maclary, E.; Osborne, E. J.; Johnson, K. P.; Huff, C. D.; Yandell, M.; Shapiro, M.
10.1101/242552 — evolutionary biology — Posted on 2018-01-05
1618 Naa10p promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas
Chien, M.-H.; Lee, W.-J.; Yang, Y.-C.; Tan, P.; Pan, K.-F.; Tsai, H.-C.; Hsu, C.-H.; Hsiao, M.; Hua, K.-T.
10.1101/243592 — cancer biology — Posted on 2018-01-05
1620 Identifying biomarkers of anti-cancer drug synergy using multi-task learning
Aben, N.; de Ruiter, J.; Bosdriesz, E.; Kim, Y.; Bounova, G.; Vis, D.; Wessels, L.; Michaut, M.
10.1101/243568 — bioinformatics — Posted on 2018-01-05
1621 Dynamics of ribosomes and release factors during translation termination in E. coli
Adio, S.; Sharma, H.; Senyushkina, T.; Karki, P.; Maracci, C.; Holtkamp, W.; Peske, F.; Rodnina, M. V.
10.1101/243485 — biochemistry — Posted on 2018-01-05
1622 The Rhodobacter sphaeroides methionine sulfoxide reductase MsrP can reduce R- and S- diastereomers of methionine sulfoxide from a broad-spectrum of protein substrates.
Tarrago, L.; Grosse, S.; Siponen, M. I.; Lemaire, D.; Alonso, B.; Miotello, G.; Armengaud, J.; Arnoux, P.; Pignol, D.; Sabaty, M.
10.1101/243626 — biochemistry — Posted on 2018-01-05
1623 Bias toward long gene misregulation in synaptic disorders can be an artefact of amplification-based methods
Raman, A. T.; Pohodich, A. E.; Wan, Y.-W.; Yalamanchili, H. K.; Lowry, B.; Zoghbi, H. Y.; Liu, Z.
10.1101/240705 — neuroscience — Posted on 2018-01-05
1626 A novel multi SNP based method for the identification of subspecies and associated lineages and sub-lineages of the Mycobacterium tuberculosis complex by whole genome sequencing
Lipworth, S. I. W.; Jajou, R.; de Neeling, H.; Bradley, P.; van der Hoek, W.; Maphalala, G.; Bonnet, M.; Sanchez-Padilla, E.; Diel, R.; Niemann, S.; Iqbal, Z.; Smith, G.; Peto, T.; Crook, D.; Walker, T. M.; van Soolingen, D.
10.1101/213850 — microbiology — Posted on 2018-01-05
1629 De novo Variants In Neurodevelopmental Disorders With Epilepsy
Heyne, H. O.; Singh, T.; Stamberger, H.; EuroEPINOMICS RES Consortium, ; Abou Jamra, R.; Caglayan, H.; Craiu, D.; De Jonghe, P.; Guerrini, R.; Helbig, K. L.; Koeleman, B. P. C.; Kosmicki, J. A.; Linnankivi, T.; May, P.; Muhle, H.; Moeller, R. S.; Neubauer, B.; Palotie, A.; Pendziwiat, M.; Striano, P.; Tang, S.; Wu, S.; Poduri, A.; Weber, Y.; Weckhuysen, S.; Sisodiya, S. M.; Daly, M.; Helbig, I.; Lal, D.; Lemke, J. R.
10.1101/123323 — genetics — Posted on 2018-01-05
1631 GSK3 Controls Migration of the Neural Crest Lineage
Gonzalez Malagon, S. G.; Lopez Munoz, A.; Doro, D.; Bolger, T.; Poon, E.; Tucker, E.; Adel Al-Lami, H.; Krause, M.; Phiel, C.; Chesler, L.; Liu, K. J.
10.1101/243170 — developmental biology — Posted on 2018-01-05
1632 Breast cancer brain metastases show increased levels of genomic aberration based homologous recombination deficiency scores relative to their corresponding primary tumors
Diossy, M.; Reiniger, L.; Sztupinszki, Z.; Krzystanek, M.; Timms, K. M.; Neff, C.; Solimeno, C.; Pruss, D.; Eklund, A. C.; Toth, E.; Kiss, O.; Rusz, O.; Cserni, G.; Zombori, T.; Szekely, B.; Csabai, I.; Szallasi, Z.
10.1101/243535 — cancer biology — Posted on 2018-01-05
1635 Modelling Signalling Networks from Perturbation Data
Dorel, M.; Klinger, B.; Sieber, A.; Prahallad, A.; Gross, T.; Bosdriesz, E.; Wessels, L.; Bluthgen, N.
10.1101/243600 — bioinformatics — Posted on 2018-01-05
1637 SLO potassium channels antagonize premature decision making in C. elegans
Aoki, I.; Tateyama, M.; Shimomura, T.; Ihara, K.; Kubo, Y.; Nakano, S.; Mori, I.
10.1101/243220 — neuroscience — Posted on 2018-01-05
1641 Identification of Pre-Existing Adaptive Immunity to Cas9 Proteins in Humans
Charlesworth, C. T.; Deshpande, P. S.; Dever, D. P.; Dejene, B.; Gomez-Ospina, N.; Mantri, S.; Pavel-Dinu, M.; Camarena, J.; Weinberg, K. I.; Porteus, M. H.
10.1101/243345 — immunology — Posted on 2018-01-05
1642 Mapping and dynamics of regulatory DNA during seed development
Sullivan, A. M.; Arsovski, A. A.; Thompson, A.; Sandstrom, R.; Thurman, R. E.; Neph, S.; Johnson, A. K.; Sullivan, S. T.; Sabo, P. J.; Neri, F. V.; Weaver, M.; Diegel, M.; Nemhauser, J. L.; Stamatoyannopoulos, J. A.; Bubb, K. L.; Queitsch, C.
10.1101/235325 — plant biology — Posted on 2018-01-04
1645 Anterior thalamic excitation and feed-forward inhibition of presubicular neurons projecting to medial entorhinal cortex
Nassar, M.; Simonnet, J.; Huang, L.-W.; Mathon, B.; Cohen, I.; Bendels, M. H.; Beraneck, M.; Miles, R.; Fricker, D.
10.1101/243022 — neuroscience — Posted on 2018-01-04
1646 Peripheral, intrareceptor inhibition in mosquito olfaction
Xu, P.; Choo, Y.-M.; Chen, Z.; Zeng, F.; Tan, K.; Chen, T.-Y.; Cornel, A. J.; Liu, N.; Leal, W. S.
10.1101/243162 — neuroscience — Posted on 2018-01-04
1648 Long Noncoding RNA-Maternally Expressed Gene 3 Contributes to Hypoxic Pulmonary Hypertension
Zhu, D.; Xing, Y.; Zheng, X.; Fu, Y.; Qi, J.; Li, M.; Peng, H.; Ma, M.; Wang, S.; Li, S.
10.1101/243063 — molecular biology — Posted on 2018-01-04
1649 Investigating the viral ecology of global bee communities with high-throughput metagenomics
Galbraith, D. A.; Fuller, Z.; Brockmann, A.; Frazier, M.; Gikungu, M. W.; Kapheim, K. M.; Kerby, J. T.; Kocher, S. D.; Losyev, O.; Muli, E.; Patch, H. M.; Sakamoto, J. M.; Stanley, S.; Vaudo, A. D.; Grozinger, C. M.
10.1101/243139 — genomics — Posted on 2018-01-04
1650 Olfactory and Vomeronasal Receptor Feedback Employ Divergent Mechanisms of PERK Activation
Dalton, R.; Karagoz, E.; Kahiapo, J.; Sharma, R.; Bashkirova, L.; Lyons, D.; Matsunami, H.; Walter, P.
10.1101/239830 — cell biology — Posted on 2018-01-04
1651 A testosterone metabolite 19-hydroxyandrostenedione induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olfactory receptor
Abaffy, T.; Bain, J. R.; Muehlbauer, M. J.; Spasojevic, I.; Lodha, S.; Bruguera, E.; Neal, S. K.; Kim, S. Y.; Matsunami, H.
10.1101/243204 — cancer biology — Posted on 2018-01-04
1654 Inferring identical by descent sharing of sample ancestors promotes high resolution relative detection
Ramstetter, M. D.; Dyer, T. D.; Lehman, D. M.; Curran, J. E.; Duggirala, R.; Blangero, J.; Mezey, J. G.; Williams, A. L.
10.1101/243048 — genetics — Posted on 2018-01-04
1655 HIV-1 unmasks the plasticity of innate lymphoid cells
Wang, Y.; Gellatly, K.; Derr, A.; Jaiswal, S.; Kucukural, A.; McDonel, P.; Greenough, T.; Houghton, J.; Garber, M.; Luban, J.
10.1101/221010 — immunology — Posted on 2018-01-04
1656 Criterion Setting is Implemented through Flexible Adjustment of Neural Excitability in Human Visual Cortex
Kloosterman, N. A.; de Gee, J. W.; Werkle-Bergner, M.; Lindenberger, U.; Garrett, D. D.; Fahrenfort, J. J.
10.1101/229989 — neuroscience — Posted on 2018-01-04
1660 UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity
Sun, J.; Liu, Y.; Jia, Y.; Tran, J.; Hao, X.; Lin, W.; Lynch, G.; Baudry, M.; Bi, X.
10.1101/242057 — neuroscience — Posted on 2018-01-04
1661 Plasmodium falciparum infection during pregnancy impairs fetal head growth: prospective and populational-based retrospective studies
Dombrowski, J. G.; Souza, R. M.; Lima, F. A.; Bandeira, C. L.; Murillo, O.; Costa, D. S.; Peixoto, E. P. M.; Cunha, M. P.; Zanotto, P. M. A.; Bevilacqua, E.; Grisotto, M. A. G.; Lima, A. C. P.; Singer, J. M.; Campino, S.; Clark, T. G.; Epiphanio, S.; Goncalves, L. A.; Marinho, C. R. F.
10.1101/203059 — epidemiology — Posted on 2018-01-04
1663 The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization
Prudencio, P.; Guilgur, L. G.; Sobral, J.; Becker, J. D.; Martinho, R. G.; Navarro-Costa, P.
10.1101/242008 — developmental biology — Posted on 2018-01-04
1664 PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation
Ronson, G.; Piberger, A. L.; Higgs, M.; Olsen, A.; Stewart, G.; McHugh, P.; Petermann, E.; Lakin, N.
10.1101/243071 — cell biology — Posted on 2018-01-04
1666 RNA-binding proteins with mixed charge domains self-assemble and aggregate in Alzheimer’s Disease
Bishof, I.; Dammer, E. B.; Duong, D. M.; Gearing, M.; Lah, J. J.; Levey, A. I.; Seyfried, N. T.
10.1101/243014 — biochemistry — Posted on 2018-01-04
1667 Fit to speak - Physical fitness is associated with reduced language decline in healthy ageing
Segaert, K.; Lucas, S. J. E.; Burley, C. V.; Segaert, P.; Milner, A. E.; Ryan, M.; Wheeldon, L.
10.1101/197095 — neuroscience — Posted on 2018-01-04
1668 Calcium channel levels at single synapses predict release probability and are upregulated in homeostatic potentiation
Gratz, S. J.; Bruckner, J. J.; Hernandez, R. X.; Khateeb, K.; Macleod, G.; O'Connor-Giles, K. M.
10.1101/240051 — neuroscience — Posted on 2018-01-04
1669 Mixed model association for biobank-scale data sets
Loh, P.-R.; Kichaev, G.; Gazal, S.; Schoech, A. P.; Price, A. L.
10.1101/194944 — genetics — Posted on 2018-01-04
1670 Reward signalling in brainstem nuclei under glycemic flux
Morville, T.; Madsen, K.; Siebner, H.; Hulme, O. J.
10.1101/243006 — neuroscience — Posted on 2018-01-04
1671 Phylogenetic distribution of roseobacticides in the Roseobacter group and their effect on microalgae
Sonnenschein, E. C.; Phippen, C. B. W.; Bentzon-Tilia, M.; Rasmussen, S. A.; Nielsen, K. F.; Gram, L.
10.1101/242842 — microbiology — Posted on 2018-01-04
1672 CHC22 Clathrin Diverts GLUT4 from the ER-to-Golgi Intermediate Compartment for Intracellular Sequestration
Camus, S. M.; Camus, M. D.; Sadacca, L. A.; Esk, C.; Gould, G. W.; Kioumourtzoglou, D.; Bryant, N. J.; Mukherjee, S.; Brodsky, F. M.
10.1101/242941 — cell biology — Posted on 2018-01-04
1674 Targeting the DNM3OS / miR-199a~214 cluster for the treatment of fibroproliferative diseases
Savary, G.; Buscot, M.; Dewaeles, E.; Diazzi, S.; Nottet, N.; Courcot, E.; Fassy, J.; Lebrigand, K.; Henaoui, I. S.; Martis, N.; Van der Hauwaert, C.; Leroy, S.; Plantier, L.; Paquet, A.; Lino Cardenas, C. L.; Vassaux, G.; Crestani, B.; Wallaert, B.; Rezzonico, R.; Brousseau, T.; Glowacki, F.; Bellusci, S.; Perrais, M.; Broly, F.; Barbry, P.; Marquette, C.-H.; Cauffiez, C.; Pottier, N.; Mari, B.
10.1101/242040 — pathology — Posted on 2018-01-04
1677 Sleep-like bistability, loss of causality and complexity in the brain of Unresponsive Wakefulness Syndrome patients
Rosanova, M.; Fecchio, M.; Casarotto, S.; Sarasso, S.; Casali, A. G.; Pigorini, A.; Comanducci, A.; Seregni, F.; Devalle, G.; Bodart, O.; Boly, M.; Gosseries, O.; Laureys, S.; Massimini, M.
10.1101/242644 — neuroscience — Posted on 2018-01-04
1679 Acute Hyperalgesia and Delayed Dry Eye After Corneal Abrasion Injury
Hegarty, D. M.; Hermes, S. M.; Morgan, M. M.; Aicher, S. A.
10.1101/242685 — neuroscience — Posted on 2018-01-04
1681 Chromatin Functional States Correlate with HIV Latency Reversal in Infected Primary CD4+ T Cells
Battivelli, E.; Dahabieh, M. S.; Abdel-Mohsen, M.; Svensson, J. P.; Tojal Da Silva, I.; Cohn, L. B.; Gramatica, A.; Deeks, S.; Greene, W. C.; Pillai, S. K.; Verdin, E.
10.1101/242958 — microbiology — Posted on 2018-01-04
1682 The Tudor protein Veneno assembles the ping-pong amplification complex that produces viral piRNAs in Aedes mosquitoes
Joosten, J.; Miesen, P.; Pennings, B.; Jansen, P. W.; Huynen, M. A.; Vermeulen, M.; Van Rij, R. P.
10.1101/242305 — microbiology — Posted on 2018-01-04
1683 B cell defects observed in Nod2 knockout mice are a consequence of a Dock2 mutation frequently found in inbred strains
Wong, S.-Y.; Coffre, M.; Ramanan, D.; Gomez, L. E.; Peters, L.; Schadt, E.; Koralov, S.; Cadwell, K.
10.1101/242586 — immunology — Posted on 2018-01-04
1684 Genome-wide association study implicates CHRNA2 in cannabis use disorder
Demontis, D.; Rajagopal, V. M.; Als, T. D.; Grove, J.; Pallesen, J.; Hjorthoj, C.; Qvist, P.; Christensen, J. H.; Bybjerg-Grauholm, J.; Baekvad-Hansen, M.; Huckins, L. M.; Stahl, E. A.; Timmermann, A.; Agerbo, E.; Hougaard, D. M.; Werge, T.; Mors, O.; Mortensen, P. B.; Nordentoft, M.; Daly, M.; Nyegaard, M.; Borglum, A. D.
10.1101/237321 — genomics — Posted on 2018-01-04
1685 Generalizing Genetic Risk Scores from Europeans to Hispanics/Latinos
Grinde, K. E.; Qi, Q.; Thornton, T. A.; Liu, S.; Shadyab, A. H.; Chan, K. H. K.; Reiner, A. P.; Sofer, T.
10.1101/242404 — genetics — Posted on 2018-01-04
1686 Genome-wide association study of 1 million people identifies 111 loci for atrial fibrillation
Nielsen, J. B.; Thorolfsdottir, R. B.; Fritsche, L. G.; Zhou, W.; Skov, M. W.; Graham, S. E.; Herron, T. J.; McCarthy, S.; Schmidt, E. M.; Sveinbjornsson, G.; Surakka, I.; Mathis, M. R.; Yamazaki, M.; Crawford, R. D.; Gabrielsen, M. E.; Skogholt, A. H.; Holmen, O. L.; Lin, M.; Wolford, B. N.; Dey, R.; Dalen, H.; Sulem, P.; Chung, J. H.; Backman, J. D.; Arnar, D. O.; Thorsteinsdottir, U.; Baras, A.; ODushlaine, C.; Holst, A. G.; Wen, X.; Hornsby, W.; Dewey, F. E.; Boehnke, M.; Kheterpal, S.; Lee, S.; Kang, H. M.; Holm, H.; Kitzman, J.; Shavit, J. A.; Jalife, J.; Brummett, C. M.; Teslovich, T. M
10.1101/242149 — genetics — Posted on 2018-01-04
1690 Symbiont switching and alternative resource acquisition strategies drive mutualism breakdown
Werner, G. D. A.; Cornelissen, J. H. C.; Cornwell, W. K.; Soudzilovskaia, N. A.; Kattge, J.; West, S. A.; Kiers, E. T.
10.1101/242834 — evolutionary biology — Posted on 2018-01-04
1691 Impacts of a millennium drought on butterfly faunal dynamics
Forister, M. L.; Fordyce, J. A.; Nice, C. C.; Thorne, J. H.; Waetjen, D. P.; Shapiro, A. M.
10.1101/242560 — ecology — Posted on 2018-01-04
1692 Mutational landscape of a chemically-induced mouse model of liver cancer
Connor, F.; Rayner, T. F.; Feig, C.; Aitken, S. J.; Lukk, M.; Odom, D. T.
10.1101/242891 — cancer biology — Posted on 2018-01-04
1693 Machine Learning approach to Predicting Stem-Cell Donor Availability
Sivasankaran, A.; Williams, E.; Switzer, G. E.; Cherkassky, V.; Maiers, M.
10.1101/242719 — bioinformatics — Posted on 2018-01-04
1697 Root Responses to Heterogeneous Nitrate Availability are Mediated by trans-Zeatin in Arabidopsis Shoots
Poitout, A.; Crabos, A.; Petrik, I.; Novak, O.; Krouk, G.; Lacombe, B.; Ruffel, S.
10.1101/242420 — plant biology — Posted on 2018-01-04
1698 A Comprehensive Tool Set for Inducible, Cell Type-Specific Gene Expression in Arabidopsis
Schuerholz, A.-K.; Lopez-Salmeron, V.; Li, Z.; Forner, J.; Wenzl, C.; Gaillochet, C.; Augustin, S.; Vilches Barro, A.; Fuchs, M.; Gebert, M.; Vermeer, J. E. M.; Lohmann, J. U.; Greb, T.; Wolf, S.
10.1101/242347 — plant biology — Posted on 2018-01-04
1699 Acetylcholine-dependent phasic dopamine activity signals exploratory locomotion and choices
Naude, J.; Didienne, S.; Takillah, S.; Prevost-Solie, C.; Maskos, U.; Faure, P.
10.1101/242438 — neuroscience — Posted on 2018-01-04
1701 Inhalation frequency controls reformatting of mitral/tufted cell odor representations in the olfactory bulb
Diaz-Quesada, M.; Youngstrom, I. A.; Tsuno, Y.; Hansen, K. R.; Economo, M. N.; Wachowiak, M.
10.1101/242784 — neuroscience — Posted on 2018-01-04
1703 Uncovering temporal structure in hippocampal output patterns
Maboudi, K.; Ackermann, E.; Pfeiffer, B. E.; Foster, D. J.; Diba, K.; Kemere, C.
10.1101/242594 — neuroscience — Posted on 2018-01-04
1704 A polymer probe-based system for high density, long-lasting electrophysiological recordings across distributed neuronal circuits
Chung, J. E.; Joo, H. R.; Fan, J. L.; Liu, D. F.; Barnett, A. H.; Chen, S.; Geaghan-Breiner, C.; Karlsson, M. P.; Karlsson, M.; Lee, K. Y.; Liang, H.; Magland, J. F.; Mehaffey, W. H.; Tooker, A. C.; Brainard, M. S.; Greengard, L. F.; Tolosa, V. M.; Frank, L. M.
10.1101/242693 — neuroscience — Posted on 2018-01-04
1705 Efficient neural decoding of spatial location with a deep recurrent network
Tampuu, A.; Matiisen, T.; Olafsdottir, H. F.; Barry, C.; Vicente, R.
10.1101/242867 — neuroscience — Posted on 2018-01-04
1707 A novel polymorphism in nitric oxide synthase interacting protein (NOSIP) modulates nitric oxide synthesis and influences mortality in human sepsis
Mukherjee, R.; Singh, D. K.; Barman, P. K.; Prusty, B. K.; Thatoi, P.; Tripathy, R.; Das, B. K.; Ravindran, B.
10.1101/038398 — immunology — Posted on 2018-01-04
1708 Whole genome and transcriptome maps of the entirely black native Korean chicken breed Yeonsan Ogye
Sohn, J.-i.; Nam, K.; Kim, J.-M.; Hong, H.; Lim, D.; Lee, K.-T.; Do, Y. J.; Cho, C. Y.; Kim, N.; Nam, J.-W.; Chae, H.-H.
10.1101/224311 — genomics — Posted on 2018-01-04
1709 Putative bovine topological association domains and CTCF binding motifs can reduce the search space for causative regulatory variants of complex traits
Wang, M.; Hancock, T. P.; Chamberlain, A. J.; Vander Jagt, C. J.; Pryce, J. E.; Cocks, B. G.; Goddard, M. E.; Hayes, B. J.
10.1101/242792 — genomics — Posted on 2018-01-04
1710 The Shared Genetic Basis of Human Fluid Intelligence and Brain Morphology
Ge, T.; Chen, C.-Y.; Vettermann, R.; Tuominen, L. J.; Holt, D. J.; Sabuncu, M. R.; Smoller, J. W.
10.1101/242776 — genetics — Posted on 2018-01-04
1711 Synchronous diversification of Sulawesi’s iconic artiodactyls driven by recent geological events
Frantz, L.; Rudzinski, A.; Mansyursyah Surya Nugraha, A.; Evin, A.; Burton, J.; Hulme-Beaman, A.; Linderholm, A.; Barnett, R.; Vega, R.; Irving-Pease, E.; Haile, J.; Allen, R.; Leus, K.; Shephard, J.; Hillyer, M.; Gillemot, S.; van den Hurk, J.; Ogle, S.; Atofanei, C.; Thomas, M.; Johansson, F.; Mustari, A.; Williams, J.; Mohamad, K.; Damayanti, C.; Wiryadi, I.; Obbles, D.; Day, H.; Yasin, M.; Meker, S.; McGuire, J.; Evans, B.; von Rintelen, T.; Ho, S.; Searle, J.; Kitchener, A.; Macdonald, A.; Shaw, D.; Hall, R.; Galbusera, P.; Larson, G.
10.1101/241448 — evolutionary biology — Posted on 2018-01-04
1712 Asymmetric histone incorporation during DNA replication in Drosophila male germline stem cells
Wooten, M.; Nizami, Z.; Yang, X.; Snedeker, J.; Ranjan, R.; Kim, J. M.; Urban, E.; Tran, V.; Buss, J.; Gall, J.; Xiao, J.; Chen, X.
10.1101/242768 — developmental biology — Posted on 2018-01-04
1716 Breast Cancer Histopathological Image Classification: A Deep Learning Approach
Habibzadeh Motlagh, N.; Jannesary, M.; Aboulkheyr, H.; Khosravi, P.; Elemento, O.; Totonchi, M.; Hajirasouliha, I.
10.1101/242818 — bioinformatics — Posted on 2018-01-04
1718 No evidence that more physically attractive women have higher estradiol or progesterone
Jones, B. C.; Hahn, A. C.; Fisher, C. I.; Wang, H.; Kandrik, M.; Lao, J.; Han, C.; Lee, A. J.; Holzleitner, I. J.; DeBruine, L. M.
10.1101/136515 — animal behavior and cognition — Posted on 2018-01-04
1720 An Epiblast Stem Cell derived multipotent progenitor population for axial extension
Edri, S.; Hayward, P.; Baillie-Johnson, P.; Steventon, B.; Martinez Arias, A.
10.1101/242461 — developmental biology — Posted on 2018-01-04
1722 Viral gain-of-function experiments uncover residues under diversifying selection in nature
Maddamsetti, R.; Johnson, D. T.; Spielman, S. J.; Petrie, K. L.; Marks, D. S.; Meyer, J. R.
10.1101/242495 — evolutionary biology — Posted on 2018-01-03
1724 Selective attention controls olfaction in rodents
Carlson, K. S.; Gadziola, M. A.; Dauster, E. S.; Wesson, D. W.
10.1101/236331 — neuroscience — Posted on 2018-01-03
1725 Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community
Yan, J.; Grantham, M.; Pantelic, J.; Bueno de Mesquita, P. J.; Albert, B.; Liu, F.; Ehrman, S.; Milton, D. K.; EMIT Consortium,
10.1101/194985 — epidemiology — Posted on 2018-01-03
1730 Temporally feathered intensity modulated radiation therapy: a planning technique to reduce normal tissue toxicity
Alfonso, J. C. L.; Parsai, S.; Joshi, N.; Godley, A.; Shah, C.; Koyfman, S. A.; Caudell, J. J.; Fuller, C. D.; Enderling, H.; Scott, J.
10.1101/184044 — biophysics — Posted on 2018-01-03
1731 The GCTx format and cmap{Py, R, M} packages: resources for the optimized storage and integrated traversal of dense matrices of data and annotations
Enache, O. M.; Lahr, D. L.; Natoli, T. E.; Litichevskiy, L.; Wadden, D.; Flynn, C.; Gould, J.; Asiedu, J. K.; Narayan, R.; Subramanian, A.
10.1101/227041 — bioinformatics — Posted on 2018-01-03
1734 Phylofactorization - a graph partitioning algorithm to identify phylogenetic scales of ecological data
Washburne, A. D.; Silverman, J. D.; Morton, J. T.; Becker, D.; Crowley, D.; Mukherjee, S.; David, L. A.; Plowright, R. K.
10.1101/235341 — ecology — Posted on 2018-01-03
1735 DeepSimulator: a deep simulator for Nanopore sequencing
Li, Y.; Han, R.; Bi, C.; Li, M.; Wang, S.; Gao, X.
10.1101/238683 — bioinformatics — Posted on 2018-01-03
1737 meaRtools: an R package for the Comprehensive Analysis of Neuronal Networks Recorded on Multi-Electrode Arrays
Gelfman, S.; Wang, Q.; Lu, Y.-F.; Hall, D.; Bostick, C.; Dhindsa, R.; Halvorsen, M.; McSweeney, K. M.; Cotterill, E.; Edinburgh, T.; Petrovski, S.; Boland, M. J.; Allen, A. S.; Goldstein, D. B.; Eglen, S. J.
10.1101/242065 — neuroscience — Posted on 2018-01-03
1739 Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
Bunnik, E. M.; Cook, K. B.; Varoquaux, N.; Batugedara, G.; Prudhomme, J.; Shi, L.; Andolina, C.; Ross, L. S.; Brady, D.; Fidock, D. A.; Nosten, F.; Tewari, R.; Sinnis, P.; Ay, F.; Vert, J.-P.; Noble, W.; Le Roch, K. G.
10.1101/242123 — systems biology — Posted on 2018-01-03
1741 Isolation of nucleic acids from low biomass samples: detection and removal of sRNA contaminants
Heintz-Buschart, A.; Yusuf, D.; Kaysen, A.; Etheridge, A.; Fritz, J. V.; May, P.; de Beaufort, C.; Upadhyaya, B. B.; Ghosal, A.; Galas, D. J.; Wilmes, P.
10.1101/232975 — molecular biology — Posted on 2018-01-03
1742 The genome of the water strider Gerris buenoi reveals expansions of gene repertoires associated with adaptations to life on the water
Armisen, D.; Rajakumar, R.; Friedrich, M.; Benoit, J. B.; Robertson, H. M.; Panfilio, K. A.; Ahn, S.-J.; Poelchau, M. F.; Chao, H.; Dinh, H.; Doddapaneni, H.; Dugan-Perez, S.; Gibbs, R. A.; Hughes, D. S.; Han, Y.; Lee, S. L.; Murali, S. C.; muzny, D. M.; Qu, J.; Worley, K. C.; Munoz-Torres, M.; Abouheif, E.; Bonneton, F.; Chen, T.; Childers, C.; Cridge, A. G.; Crumiere, A. J.; Decaras, A.; Didion, E. M.; Duncan, E.; Elpidina, E. N.; Fave, M.-J.; Finet, C.; Jacobs, C. G.; Jarvela, A.; Jennings, E. J.; Jones, J. W.; Lesoway, M. P.; Lovegrove, M.; Martynov, A.; Oppert, B.; Lilico-Ouachour, A.; Ra
10.1101/242230 — genomics — Posted on 2018-01-03
1744 A butterfly chromonome reveals selection dynamics during extensive and cryptic chromosomal reshuffling
Hill, J. A.; Neethiraj, R.; Rastas, P.; Clark, N.; Morehouse, N.; de la Paz Celorio-Mancera, M.; Cols, J. C.; Dircksen, H.; Meslin, C.; Sikkink, K.; Vives, M.; Vogel, H.; Wiklund, C.; Boggs, C. L.; Nylin, S.; Wheat, C.
10.1101/233700 — evolutionary biology — Posted on 2018-01-03
1751 Cross-Modal Cue Effects in Motion Transparency Processing
Hanada, G. M.; Ahveninen, J.; Calabro, F. J.; Yengo-Kahn, A.; Vaina, L. M.
10.1101/242214 — neuroscience — Posted on 2018-01-03
1752 Aged blood inhibits hippocampal neurogenesis and activates microglia through VCAM1 at the blood-brain barrier
Yousef, H.; Czupalla, C. J.; Lee, D.; Burke, A.; Chen, M.; Zandstra, J.; Berber, E.; Lehallier, B.; Mathur, V.; Nair, R. V.; Bonanno, L.; Merkel, T.; Schwaninger, M.; Quake, S.; Butcher, E. C.; Wyss-Coray, T.
10.1101/242198 — neuroscience — Posted on 2018-01-03
1754 Whole genome and transcriptome maps of the entirely blacknative Korean chicken breed Yeonsan Ogye
Sohn, J.-i.; Nam, K.; Kim, J.-M.; Hong, H.; Lim, D.; Lee, K.-T.; Do, Y. J.; Cho, C. Y.; Kim, N.; Nam, J.-W.; Chae, H.-H.
10.1101/224311 — genomics — Posted on 2018-01-03
1755 The genomic footprint of climate adaptation in Chironomus riparius
Waldvogel, A.-M.; Wieser, A.; Schell, T.; Patel, S.; Schmidt, H.; Hankeln, T.; Feldmeyer, B.; Pfenninger, M.
10.1101/118190 — evolutionary biology — Posted on 2018-01-03
1757 Measuring mosquito-borne viral suitability and its implications for Zika virus transmission in Myanmar
Perez, P. N.; Alcantara, L. C.; Obolski, U.; Maia de Lima, M.; Ashley, E.; Smithuis, F.; Horby, P.; Maude, R. J.; Lourenco, J.
10.1101/231373 — epidemiology — Posted on 2018-01-03
1759 Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
Bunnik, E. M.; Cook, K. B.; Varoquaux, N.; Batugedara, G.; Prudhomme, J.; Shi, L.; Andolina, C.; Ross, L. S.; Brady, D.; Fidock, D. A.; Nosten, F.; Tewari, R.; Sinnis, P.; Ay, F.; Vert, J.-P.; Noble, W.; Le Roch, K. G.
10.1101/242123 — systems biology — Posted on 2018-01-02
1760 meaRtools: an R package for the Comprehensive Analysis of Neuronal Networks Recorded on Multi-Electrode Arrays
Gelfman, S.; Wang, Q.; Lu, Y.-F.; Hall, D.; Bostick, C.; Dhindsa, R.; Halvorsen, M.; McSweeney, K. M.; Cotterill, E.; Edinburgh, T.; Petrovski, S.; Boland, M. J.; Allen, A. S.; Goldstein, D. B.; Eglen, S. J.
10.1101/242065 — neuroscience — Posted on 2018-01-02
1762 DAtest: a framework for choosing differential abundance or expression method
Russel, J.; Thorsen, J.; Brejnrod, A. D.; Bisgaard, H.; Sorensen, S. J.; Burmolle, M.
10.1101/241802 — bioinformatics — Posted on 2018-01-02
1764 Digital museum of retinal ganglion cells with dense anatomy and physiology
Bae, J. A.; Mu, S.; Kim, J. S.; Turner, N. L.; Tartavull, I.; Kemnitz, N.; Jordan, C. S.; Norton, A. D.; Silversmith, W. M.; Prentki, R.; Sorek, M.; David, C.; Jones, D. L.; Bland, D.; Sterling, A. L. R.; Park, J.; Briggman, K. L.; Seung, H. S.; the EyeWirers,
10.1101/182758 — neuroscience — Posted on 2018-01-02
1767 Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site
Molinski, S. V.; Shahani, V. M.; Subramanian, A. S.; MacKinnon, S. S.; Woollard, G.; Laforet, M.; Laselva, O.; Morayniss, L. D.; Bear, C. E.; Windemuth, A.
10.1101/242073 — biochemistry — Posted on 2018-01-02
1768 Dynamin-2 facilitates Atg9 recycling from nascent autophagosomes
Martorell Riera, A.; Iriondo Martinez, C.; Itskanov, S.; Steffen, J.; Roach, B.; Koehler, C. M.; Van der Bliek, A. M.
10.1101/241901 — cell biology — Posted on 2018-01-02
1770 Organization of Area hV5/MT+ in Subjects with Homonymous Visual Field Defects
Papanikolaou, A.; Keliris, G. A.; Papageorgiou, T. D.; Schiefer, U.; Logothetis, N. K.; Smirnakis, S. M.
10.1101/241836 — neuroscience — Posted on 2018-01-02
1772 Active avoidance requires inhibitory signaling in the rodent prelimbic prefrontal cortex
Diehl, M. M.; Bravo-Rivera, C.; Rodriguez-Romaguera, J.; Pagan-Rivera, P. A.; Burgos-Robles, A.; Quirk, G.
10.1101/241943 — neuroscience — Posted on 2018-01-02
1774 Representativeness and robustness of TCR repertoire diversity assessment by high-throughput sequencing
Chaara, W.; Mariotti-Ferrandiz, E.; Gonzalez-Tort, A.; Florez, L.; Six, A.; Klatzmann, D.
10.1101/242024 — immunology — Posted on 2018-01-02
1775 Euchromatic histone methyltransferases regulate peripheral heterochromatin tethering via histone and non-histone protein methylations
Ketkar, A. A.; Rao, R. A.; Kedia, N.; Ravindran, F.; Lakshmanan, V.; Kumar, P.; Mohanty, A.; Kumar, S.; Raja, S. O.; Gulyani, A.; Chaturvedi, C.; Brand, M.; Palakodeti, D.; Rampalli, S.
10.1101/240952 — genetics — Posted on 2018-01-02
1778 Dense reconstruction of brain-wide neuronal population close to the ground truth
Zhou, H.; Li, S.; Li, A.; Feng, X.; Li, N.; Han, J.; Kang, H.; Chen, Y.; Li, Y.; Fang, W.; Liu, Y.; Lin, H.; Jin, S.; Li, Z.; Xu, F.; Zhang, Y.-h.; Lv, X.; Liu, X.; Gong, H.; Luo, Q.; Quan, T.; Zeng, S.
10.1101/223834 — neuroscience — Posted on 2018-01-02
1781 Discordant association of the CREBRF rs373863828 minor allele with increased body mass index and protection from type 2 diabetes in Maori and Pacific (Polynesian) people living in Aotearoa New Zealand
Krishnan, M.; Major, T. J.; Topless, R. K.; Dewes, O.; Yu, L.; Thompson, J. M.; McCowan, L.; de Zoysa, J.; Stamp, L. K.; Dalbeth, N.; Harre Hindmarsh, J.; Rapana, N.; Deka, R.; Eng, W. W.; Weeks, D. E.; Minster, R. L.; McGarvey, S. T.; Viali, S.; Naseri, T.; Reupena, M.; Wilcox, P.; Grattan, D.; Shepherd, P. R.; Shelling, A. N.; Murphy, R.; Merriman, T. R.
10.1101/188110 — genetics — Posted on 2018-01-02
1783 The effectiveness of glass beads for plating cell cultures
Prusokas, A.; Hawkins, M.; Nieduszynski, C.; Retkute, R.
10.1101/241752 — biophysics — Posted on 2018-01-02
1784 NanoPack: visualizing and processing long read sequencing data
De Coster, W.; D'Hert, S.; Schultz, D. T.; Cruts, M.; Van Broeckhoven, C.
10.1101/237180 — bioinformatics — Posted on 2018-01-02
1786 Phospholipid flipping facilitates annexin translocation across membranes
Stewart, S. E.; Ashkenazi, A.; Williamson, A.; Rubinsztein, D. C.; Moreau, K.
10.1101/241976 — cell biology — Posted on 2018-01-02
1789 Chromosome Removal Via Cellular Fragmentation and Aneuploid Blastomere Exclusion in Primate Embryos
Daughtry, B. L.; Rosenkrantz, J. L.; Lazar, N. H.; Fei, S. S.; Redmayne, N.; Torkenczy, K. A.; Adey, A.; Gao, L.; Park, B.; Nevonen, K. A.; Carbone, L.; Chavez, S. L.
10.1101/241851 — developmental biology — Posted on 2018-01-02
1790 Dynamin-2 facilitates Atg9 recycling from nascent autophagosomes
Martorell Rivera, A.; Iriondo Martinez, C.; Itskanov, S.; Steffen, J.; Roach, B.; Koehler, C. M.; Van der Bliek, A. M.
10.1101/241901 — cell biology — Posted on 2018-01-02
1801 Using insects to detect, monitor and predict the distribution of Xylella fastidiosa: a case study in Corsica
Cruaud, A.; Gonzalez, A.-A.; Godefroid, M.; Nidelet, S.; Streito, J.-C.; Thuillier, J.-M.; Rossi, J.-P.; Santoni, S.; Rasplus, J.-Y.
10.1101/241513 — ecology — Posted on 2018-01-01
1802 DECODE-ing sparsity patterns in single-cell RNA-seq
Mohammadi, S.; Davila-Velderrain, J.; Kellis, M.; Grama, A.
10.1101/241646 — bioinformatics — Posted on 2018-01-01
1804 Glucocorticoid-Induced Metabolic Disturbances are Exacerbated in Obesity
Harvey, I.; Stephenson, E. J.; Redd, J. R.; Tran, Q. T.; Hochberg, I.; Qi, N.; Bridges, D.
10.1101/184507 — physiology — Posted on 2018-01-01
1806 Understanding How Microbiomes Influence the Systems they Inhabit: Moving from a correlative to a causal research framework
Hall, E.; Bernhardt, E.; Bier, R.; Bradford, M.; Boot, C.; Cotner, J.; del Giorgio, P.; Evans, S.; Graham, E.; Jones, S.; Lennon, J.; Locey, K.; Nemergut, D.; Osborne, B.; Rocca, J.; Schimel, J.; Wallenstein, M.
10.1101/065128 — microbiology — Posted on 2018-01-01
1807 Acoustically Targeted Chemogenetics for Noninvasive Control of Neural Circuits
Szablowski, J. O.; Lue, B.; Lee-Gosselin, A.; Malounda, D.; Shapiro, M. G.
10.1101/241406 — neuroscience — Posted on 2018-01-01
1809 The effectiveness of glass beads for plating cell cultures
Prusokas, A.; Hawkins, M.; Nieduszynski, C.; Retkute, R.
10.1101/241752 — biophysics — Posted on 2018-01-01
1810 Mammalian genomic regulatory regions predicted by utilizing human genomics, transcriptomics and epigenetics data
Nguyen, Q. H.; Tellam, R. L.; Naval-Sanchez, M.; Porto-Neto, L. R.; Barendse, W.; Reverter, A.; Hayes, B. J.; Kijas, J. W.; Dalrymple, B. P.
10.1101/143990 — genomics — Posted on 2018-01-01