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Archive, 2024-10

3 Diminished placental Factor XIIIA1 expression associates with long term ART and preterm birth in pregnant people living with HIV.
Ojwach, D.; Annels, N.; Sunshine, S.; Simpkin, D.; Duruanyanwu, J.; Webber, T.; Alinde, B.; Ikumi, N.; Zulu, M.; Madlala, H.; Myer, L.; Malaba, T.; Newell, M.-L.; Campagnolo, P.; Gordon, S.; Jaspan, H. B.; Gray, C.; Martinez Estrada, F.
10.1101/2024.10.30.620906 — immunology — Posted on 2024-10-31
5 Practice beyond performance stabilization increases the use of online adjustments to unpredictable perturbations in an interceptive task
Couto, C.; Leite, C.; Campos, C.; Portes, L.; Matos, C.; Santos, S.; Ambrosio, N.; Yehia, H. C.; Ugrinowitsch, H.
10.1101/2024.10.30.621165 — neuroscience — Posted on 2024-10-31
9 Inosculation As A Tool For Living Architecture: Methods And Early Results
Faucon, P.; Fertet, A.; Bombail, A.; Gouguec, C.; Montil, C.; de la Sayette, A.
10.1101/2024.10.30.621064 — plant biology — Posted on 2024-10-31
11 Genomic surveillance and molecular evolution of fungicide resistance in European populations of wheat powderymildew
Minadakis, N.; Jigisha, J.; Cornetti, L.; Kunz, L.; Mueller, M. C.; Torriani, S. F.; Menardo, F.
10.1101/2024.10.30.621051 — pathology — Posted on 2024-10-31
12 5-methylcytosine and 5-hydroxymethylcytosine are synergistic biomarkers for early detection of colorectal cancer
Puddu, F.; Johansson, A.; Modat, A.; Scotcher, J.; Sethi, R.; Harding, N.; Hill, M.; Lleshi, E.; Teyssandier, J.; Crawford, R.; Charlesworth, T.; Osborne, R. J.; Balasubramanian, S.; Creed, P.; Yu, S.; Lumby, C.; Wilson, M.
10.1101/2024.10.30.621123 — cancer biology — Posted on 2024-10-31
13 Sequence clustering with PaSiMap in Jalview
Morell, T.; Procter, J.; Barton, G. J.; Diederichs, K.; Mayans, O.; Fleming, J. R.
10.1101/2024.10.30.621149 — biochemistry — Posted on 2024-10-31
15 GENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing
Kaur, G.; Perteghella, T.; Carbonell-Sala, S.; Gonzalez-Martinez, J.; Hunt, T.; Madry, T.; Jungreis, I.; Arnan, C.; Lagarde, J.; Borsari, B.; Sisu, C.; Jiang, Y.; Bennett, R.; Berry, A.; Cerdan-Velez, D.; Cochran, K.; Vara, C.; Davidson, C.; Donaldson, S.; Dursun, C.; Gonazlez-Lopez, S.; Gopal Das, S.; Hardy, M.; Hollis, Z.; Kay, M.; Montanes, J. C.; Ni, P.; Nurtdinov, R.; Palumbo, E.; Pulido-Quetglas, C.; Suner, M.-M.; Yu, X.; Zhang, D.; Loveland, J. E.; Alba, M. M.; Diekhans, M.; Tanzer, A.; Mudge, J. M.; Flicek, P.; Martin, F. J.; Gerstein, M.; Kellis, M.; Kundaje, A.; Paten, B.; Tress, M.
10.1101/2024.10.29.620654 — genomics — Posted on 2024-10-31
16 The global dispersal of visceral leishmaniasis occurred within human history
Reis-Cunha, J. L.; Grace, C. A.; Ahmed, S.; Harnqvist, S. E.; Lynch, C. M.; Boite, M. C.; Barcellos, G.; Lachaud, L.; Bastien, P.; Munt, H.; Mottram, J. C.; Cupolillo, E.; Jeffares, D. C.
10.1101/2024.10.30.621037 — evolutionary biology — Posted on 2024-10-31
17 Saltational episodes of reticulate evolution in the Drosophila saltans species group
Prediger, C.; Ferreira, E. A.; Zorzato, S. V.; Hua-Van, A.; Klasson, L.; Miller, W.; Yassin, A.; Madi-Ravazzi, L.
10.1101/2023.10.09.561511 — evolutionary biology — Posted on 2024-10-31
18 Aridity and coexistence with vascular plants determine the dynamics of coastal dune bryophyte communities
Varela, Z.; Chozas, S.; Lobo, S.; Giraldez, P.; Monteiro, J.; Branquinho, C.; Hortal, J.
10.1101/2024.10.29.620786 — ecology — Posted on 2024-10-31
20 Shared pathway-specific network mechanisms of dopamine and deep brain stimulation for the treatment of Parkinson's disease
Binns, T. S.; Köhler, R. M.; Vanhoecke, J.; Chikermane, M.; Gerster, M.; Merk, T.; Pellegrini, F.; Busch, J. L.; Habets, J. G. V.; Cavallo, A.; Beyer, J.-C.; Al-Fatly, B.; Li, N.; Horn, A.; Krause, P.; Faust, K.; Schneider, G.-H.; Haufe, S.; Kühn, A. A.; Neumann, W.-J.
10.1101/2024.04.14.586969 — neuroscience — Posted on 2024-10-31
27 Revolutionizing large-scale DNA synthesis with microchip-based massive in parallel synthesis system
Zhang, X.; Jiang, X.; Wang, Y.; Chen, Q.; Zhang, R.; Jiang, H.; Zhang, H.; Beltran, A.; Yang, W.; Liang, C.; Chen, N.; Huang, Y.; Ding, G.; Xie, C.; Gao, N.; Zheng, K.; Liu, J.; Xu, W.; Huang, J.; Cai, D.; Zhu, L.; Mo, S.; Shen, M.; Zhang, W.; Lehner, B.; Ni, M.; Wang, J.; Xu, X.; Shen, Y.
10.1101/2024.10.30.619547 — synthetic biology — Posted on 2024-10-31
28 Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Masson, C.; Scandola, C.; Rinckel, J.-Y.; Proamer, F.; Janus-Bell, E.; Batool, F.; OSMANI, N.; GOETZ, J. G.; Mallo, L.; Leon, C.; Bornert, A.; Poincloux, R.; destaing, o.; Mansson, A.; QIAN, H.; Lehmann, M.; Eckly, A.
10.1101/2024.09.30.615769 — physiology — Posted on 2024-10-31
31 A circuit involving the lncRNA MB3 and the driver genes MYC and OTX2 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5
Grandioso, A.; Tollis, P.; Pellegrini, F. R.; Falvo, E.; Palma, A.; Migliaccio, F.; Belvedere, A.; Rea, J.; Tisci, G.; Carissimo, A.; Bozzoni, I.; Trisciuoglio, D.; Ballarino, M.; Ceci, P.; Laneve, P.
10.1101/2024.10.21.619459 — cancer biology — Posted on 2024-10-31
32 Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts
Weinfurtner, K.; Tischfield, D.; McClung, G.; Crainic, J.; Gordan, J.; Jiao, J.; Furth, E. E.; Li, W.; Tuzneen Supan, E.; Nadolski, G. J.; Hunt, S. J.; Kaplan, D. E.; Gade, T. P.
10.1101/2023.10.05.561117 — cancer biology — Posted on 2024-10-31
33 Thoracic Aortic Three-Dimensional Geometry
Beeche, C.; Dib, M.-J.; Zhao, B.; Azzo, J.-D.; Tavolinejad, H.; Maynard, H.; Duda, J.; Gee, J.; Salman, O.; Witschey, W.; Chirinos, J.
10.1101/2024.05.09.593413 — bioinformatics — Posted on 2024-10-31
34 Effect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages
Wychowaniec, J. K.; Bektas, E. I.; Vernengo, A. J.; Mürner, M.; Airoldi, M.; Tipay, P. S.; Sapudom, J.; Teo, J.; Eglin, D.; D'Este, M.
10.1101/2024.01.11.575241 — bioengineering — Posted on 2024-10-31
37 Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of RNA sensor MDA5 in atherosclerosis
Weldy, C. S.; Li, Q.; Monteiro, J. P.; Guo, H.; Galls, D.; Gu, W.; Cheng, P. P.; Ramste, M.; Li, D. Y.; Palmisano, B. T.; Sharma, D.; Worssam, M. D.; Zhao, Q.; Bhate, A.; Kundu, R.; Nguyen, T.; Li, J. B.; Quertermous, T.
10.1101/2024.07.08.602569 — genomics — Posted on 2024-10-31
38 DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project
Mariner, B. L.; McCoy, B. M.; Greenier, A.; Brassington, L.; Slikas, E.; Adjangba, C.; Marye, A.; Harrison, B. R.; Bamberger, T.; Algavi, Y.; Muller, E.; Harris, A.; Rout, E.; The Dog Aging Project Consortium, ; Avery, A.; Borenstein, E.; Promislow, D.; Snyder-Mackler, N.
10.1101/2024.10.08.617286 — genomics — Posted on 2024-10-31
43 p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD
Regnier, M.; Polizzi, A.; Fougeray, T.; Fougerat, A.; Perrier, P.; Anderson, K.; Lippi, Y.; Smati, S.; Lukowicz, C.; Lasserre, F.; Fouche, E.; Huillet, M.; Rives, C.; Tramunt, B.; Naylies, C.; Garcia, G.; Rousseau-Bacquie, E.; Bertrand-Michel, J.; Canlet, C.; Chevolleau-Mege, S.; Debrauwer, L.; Heymes, C.; Burcelin, R.; Levade, T.; Gourdy, P.; Wahli, W.; Blum, Y.; Gamet-Payrastre, L.; Ellero-Simatos, S.; Guillermet-Guibert, J.; Hawkins, P.; Stephens, L.; Postic, C.; Montagner, A.; Loiseau, N.; Guillou, H.
10.1101/2024.01.09.574858 — cell biology — Posted on 2024-10-31
44 Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
Raig, N. D.; Surridge, K. J.; Sanz-Murillo, M.; Dederer, V.; Kramer, A.; Schwalm, M. P.; Elson, L.; Chatterjee, D.; Mathea, S.; Hanke, T.; Leschziner, A. E.; Reck-Peterson, S. L.; Knapp, S.
10.1101/2024.09.17.613365 — cell biology — Posted on 2024-10-31
45 Chromatin-associated lncRNA-splicing factor condensates regulate hypoxia responsive RNA processing of genes pre-positioned near nuclear speckles
Song, Y. J.; Shinn, M. K.; Bangru, S.; Wang, Y.; Sun, Q.; Hao, Q.; Chaturvedi, P.; Freier, S. M.; Perez-Pinera, P.; Nelson, E. R.; Belmont, A. S.; Guttman, M.; Prasantth, S. G.; Kalsotra, A.; Pappu, R. V.; Kannanganattu, P. V.
10.1101/2024.10.31.621310 — molecular biology — Posted on 2024-10-31
46 Host PIK3C3 promotes Shigella flexneri spread from cell to cell through vacuole formation
Rolland, S. J.; Lifschin, Z. J.; Weddle, E. A.; Yum, L. K.; Miyake, T.; Engel, D. A.; Agaisse, H. F.
10.1101/2024.10.31.621244 — microbiology — Posted on 2024-10-31
48 Glycoprotein K8.1 is Critical for Liver and Bone Marrow Tropism of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) in the Marmoset Infection Model
Hennig, C. S.; Roshani, B.; Schlagowski, S.; Grosskopf, A. K.; Merida Ruiz, S. A.; Vestweber, R.; Bleyer, M.; Stolte-Leeb, N.; Pöhlmann, S.; Whitby, D.; Ensser, A.; Hahn, A. S. S.
10.1101/2024.10.31.621273 — microbiology — Posted on 2024-10-31
49 H2 consumption by acetogenic bacteria follows first-order kinetics
Munoz, L.; Chakraborty, S.; Gron, L. V.; Bambace, M. F.; Catalano, J.; Philips, J.
10.1101/2024.05.08.593002 — microbiology — Posted on 2024-10-31
50 MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
Graca, A. P.; Nikitushkin, V.; Ellerhorst, M.; Vilhena, C.; Klassert, T.; Starick, A.; Siemers, M.; Al-Jammal, W. K.; Vilotijevic, I.; Slevogt, H.; Papenfort, K.; Lackner, G.
10.1101/2024.03.26.586840 — microbiology — Posted on 2024-10-31
52 Induction of Hepatitis B Core Protein Aggregation Targeting an Unconventional Binding Site
Khayenko, V.; Makbul, C.; Schulte, C.; Hemmelmann, N.; Kachler, S.; Boettcher, B.; Maric, H. M.
10.1101/2024.04.29.591677 — microbiology — Posted on 2024-10-31
54 Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark
Karpowicz, B. M.; Ye, J.; Fan, C.; Tostado-Marcos, P.; Rizzoglio, F.; Washington, C.; Scodeler, T.; de Lucena, D.; Nason-Tomaszewski, S. R.; Mender, M. J.; Ma, X.; Arneodo, E. M.; Hochberg, L. R.; Chestek, C. A.; Henderson, J. M.; Gentner, T. Q.; Gilja, V.; Miller, L. E.; Rouse, A. G.; Gaunt, R. A.; Collinger, J. L.; Pandarinath, C.
10.1101/2024.09.15.613126 — neuroscience — Posted on 2024-10-31
58 A MESOSCALE CONNECTOME-BASED MODEL OF CONSCIOUS ACCESS IN THE MACAQUE MONKEY
Klatzmann, U.; Froudist-Walsh, S.; Bliss, D. P.; Theodoni, P.; Mejias, J. F.; Niu, M.; Rapan, L.; Palomero-Gallagher, N.; Sergent, C.; Dehaene, S.; Wang, X.-J.
10.1101/2022.02.20.481230 — neuroscience — Posted on 2024-10-31
59 Awakening of the RuMP cycle for synthetic methylotrophy in the thermophile Parageobacillus thermoglucosidasius.
Paredes-Barrada, M.; Mathissen, A. S.; van der Molen, R. A.; Jimenez-Huesa, P. J.; Polano, M. E.; Donati, S.; Abele, M.; Ludwig, C.; van Kranenburg, R.; Claassens, N. J.
10.1101/2024.10.31.621308 — synthetic biology — Posted on 2024-10-31
62 Tomato cystatin SlCYS8 as a trigger of drought tolerance and tuber yield in potato
Dorval, M.; Langlois, A.; Tremblay, J.; Veillet, G.; Chiasson, M.-A.; Goulet, M.-C.; Gumiere, T.; Pepin, S.; Goulet, C.; Michaud, D.
10.1101/2024.09.11.612519 — plant biology — Posted on 2024-10-31
63 Replication stress inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors
Zhou, J.; Zhou, X. A.; Hu, L.; Ma, Y.; Zhan, J.; Xu, Z.; Zhou, M.; Shen, Q.; Liu, Z.; Ma, S.; Xie, Y.; Wang, J.
10.1101/2023.07.20.549893 — cancer biology — Posted on 2024-10-31
67 APOBEC3A, not APOBEC3B, drives deaminase mutagenesis in human gastric epithelium
An, Y.; Lee, J.-H.; Lim, J.; Youk, J.; Park, S.; Park, J.-H.; Yi, K.; Kim, T.; Nam, C. H.; Lee, W. H.; Oh, S. A.; Bae, Y. J.; Lee, J.; Park, J. W.; Kim, J.-H.; Kim, H.; Snippert, H.; Koo, B.-K.; Ju, Y. S.
10.1101/2024.10.28.620744 — genomics — Posted on 2024-10-31
68 PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation
Shu, Y.; Hu, S. W.; Jeong, S.; Jiang, L.; Koo, H.; Wang, Z.; Choi, W. H.; Zhu, B.; Seok, H.; Zhou, Y.; Kim, M. G.; Mu, D.; Guo, H.; Zhou, Z.; Jung, S. H.; Zhang, Y.; Chae, H. B.; Chen, L.; Lee, S.-Y.; Guo, L.; Suh, M.-W.; Xiao, Y.; Park, M. K.; Tang, H.; Song, J.-J.; Chen, X.; Chen, A.; Lee, J. H.; Bae, S.; Lee, S.-Y.
10.1101/2024.10.29.620803 — genetics — Posted on 2024-10-31
72 Hydrophobic tails enable diverse functions of the extracellular chaperone clusterin
Yuste-Checa, P.; Carvajal, A. I.; Chenchen, M.; Paatz, S.; Hartl, F.-U.; Bracher, A.
10.1101/2024.10.30.620894 — molecular biology — Posted on 2024-10-31
73 Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection
Chen, Z.-S.; Huang, H.-C.; Wang, X.; Schön, K.; Jia, Y.; Lebens, M.; Besavilla, D.; Murti, J.; Ji, Y.; Sarshad, A.; Deng, G.; Zhu, Q.; Angeletti, D.
10.1101/2024.10.31.621368 — microbiology — Posted on 2024-10-31
74 Evolutionary divergence of drug-binding sites in bacterial ribosomes
Ekemezie, C. L.; Chan, L. I.; Brown, C. R.; Helena-Bueno, K.; Williams, T.; Melnikov, S. V.
10.1101/2024.10.31.621234 — microbiology — Posted on 2024-10-31
75 Microbial succession, community assembly and adaptation over five years in a newly discovered deep-sea cold seep
Liang, Q.; Liu, X.; Wang, J.; Chen, T.; Han, Y.; Zhang, L.; Li, S.; Zhao, J.; Dong, Y.; Guo, B.; Xiao, X.; Dong, X.
10.1101/2024.10.31.619006 — microbiology — Posted on 2024-10-31
76 Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk
Marli, M. T.; Nordraak, A. O. O.; de Bakker, V.; Winther, A. R.; Liu, X.; Veening, J.-W.; Porecellato, D.; Kjos, M.
10.1101/2024.10.31.621336 — microbiology — Posted on 2024-10-31
81 Quality of vaccination-induced T cell responses is conveyed by polyclonality and high, but not maximum, antigen receptor avidity
Kocher, K.; Drost, F.; Tesfaye, A. M.; Moosmann, C.; Schuelein, C.; Grotz, M.; D'Ippolito, E.; Graw, F.; Spriewald, B.; Busch, D. H.; Bogdan, C.; Tenbusch, M.; Schubert, B.; Schober, K.
10.1101/2024.10.30.620795 — immunology — Posted on 2024-10-31
82 Antigenic imprinting dominates humoral responses to new variants of SARS-CoV-2 in a hamster model of COVID-19
Degryse, J.; Maas, E.; Lassauniere, R.; Geerts, K.; Kumpanenko, Y.; Weynand, B.; Maes, P.; Neyts, J.; Thibaut, H. J.; Alpizar, Y. A.; Dallmeier, K.
10.1101/2024.10.30.621174 — immunology — Posted on 2024-10-31
84 A Bayesian Framework for Genome-wide Circadian Rhythmicity Biomarker Detection
Ding, H.; Meng, L.; Zhang, Y.; Bryant, A. J.; Xing, C.; Esser, K. A.; Chen, L.; Huo, Z.
10.1101/2024.10.28.620703 — bioinformatics — Posted on 2024-10-31
86 Elevated temperature during rearing diminishes swimming and disturbs the metabolism of yellow perch larvae
Easwaramoorthy, M.; Thompson, W. A.; Fraz, S.; Nederveen, J.; Hartenstein, P.; Laframboise, L.; Manzon, R.; Somers, C.; Wilson, J. Y.
10.1101/2024.10.30.621200 — developmental biology — Posted on 2024-10-31
87 BROADband brain Network Estimation via Source Separation (BROAD-NESS)
Bonetti, L.; Fernandez-Rubio, G.; Andersen, M. H.; Malvaso, C.; Carlomagno, F.; Testa, C.; Vuust, P.; Kringelbach, M. L.; Rosso, M.
10.1101/2024.10.31.621257 — neuroscience — Posted on 2024-10-31
88 The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells
Weaver, M. R.; Shkoruta, D.; Pellegatta, M. R.; Berti, C.; Palmisano, M.; Ferguson, S.; Hurley, E.; French, J.; Patel, S.; Belin, S.; Selbach, M.; Paul, F. E.; Sim, F.; Poitelon, Y.; Feltri, M. L.
10.1101/2024.10.30.620661 — neuroscience — Posted on 2024-10-31
90 Lipid Disbalance Affects Neuronal Dendrite Growth and Maintenance in a Human Ceramide Synthase Disease Model
Ziegler, A. B.; Wesselmann, C.; Beckschaefer, K.; Wulf, A.-L.; Dhiman, N.; Soba, P.; Thiele, C.; Bauer, R.; Tavosanis, G.
10.1101/2024.10.31.621235 — neuroscience — Posted on 2024-10-31
91 Multiscale Quantification of Hemispheric Asymmetry in Cortical Maps Using Geometric Eigenmodes
Milloz, A.; Vogel, J.; Olsen, A.; Pang, J. C.; Strandberg, O.; Anijärv, T. E.; Stomrud, E.; Palmqvist, S.; Spotorno, N.; Ossenkoppele, R.; Van De Ville, D.; Hansson, O.; Behjat, H.
10.1101/2024.10.31.621232 — neuroscience — Posted on 2024-10-31
93 Sex and Region-Specific Disruption of Autophagy and Mitophagy in Alzheimer's Disease: Linking Cellular Dysfunction to Cognitive Decline
Adlimoghaddam, A.; Fayazbakhsh, F.; Mohammadi, M.; Babaei, Z.; Behrooz, A. B.; Tabasi, F.; Guan, T.; Behshti, I.; Aghaei, M.; Klionsky, D. J.; Albensi, B. C.; Ghavami, S.
10.1101/2024.10.30.621097 — neuroscience — Posted on 2024-10-31
94 A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit
Sun, J.; Rojo-Cortes, F. R.; Ulian-Benitez, S.; Forero, M. G.; Li, G.; Singh, D.; Wang, X.; Cachero, S.; Moreira, M.; Kavanagh, D.; Jefferis, G. S. X. E.; Croset, V.; Hidalgo, A.
10.1101/2023.01.04.522695 — neuroscience — Posted on 2024-10-31
98 The persistent effects of predator odor stressor enhance interoceptive sensitivity to alcohol through GABA-A receptor adaptations in the prelimbic cortex in male, but not female rats
Tyler, R. E.; Bluitt, M. N.; Voorhies, K. J.; Liu, W.; Magee, S. N.; Pitrolo, E. R.; Cordero, V. L.; Ornelas, L. C.; Krieman, C. G.; Bender, B. N.; Moresa, A. M.; Besheer, J.
10.1101/2024.10.30.621141 — neuroscience — Posted on 2024-10-31
101 Impaired maturation of wild-type superoxide dismutase 1 associated with neurodegeneration in Parkinson disease brain and a novel murine model
Abdeen, A. H.; Trist, B. G.; Nikseresht, S.; Harwood, R.; Roudeau, S.; Rowlands, B. D.; Kreilaus, F.; Cottam, V.; Mor, D.; Richardson, M.; Siciliano, J.; Forkgen, J.; Schaffer, G.; Genoud, S.; Li, A. A.; Proschogo, N.; Antonio, B.; Falkenberg, G.; Brueckner, D.; Kysenius, K.; Liddell, J. R.; Fat, S. C. M.; Wu, S.; Fifita, J.; Lockwood, T. E.; Bishop, D. P.; Blair, I.; Ortega, R.; Crouch, P. J.; Double, K. L.
10.1101/2024.10.29.620972 — neuroscience — Posted on 2024-10-31
104 A Protocol for Neuralized Murine Olfactory Organoids
Ozgun, A.; Suman, P.; Coulombe, J.; aSCENT-PD Investigators, ; Brown, E. G.; Tomlinson, J. J.; Woulfe, J. M.; Schlossmacher, M. G.
10.1101/2024.10.29.620938 — neuroscience — Posted on 2024-10-31
106 Mental Rotation is a weak measure of the propensity to visualise.
Arnold, D. H.; Bouyer, L. N.; Saurels, B. H.; Pellicano, E.; Schwarzkopf, D. S. H.
10.1101/2024.10.29.620977 — neuroscience — Posted on 2024-10-31
112 A Novel Human TBCK- Neuronal Cell Model Results in Severe Neurodegeneration and Partial Rescue with Mitochondrial Fission Inhibition
Angireddy, R.; Murali, S.; Karisetty, B. C.; Kossenkov, A.; Katsura, K.; Ohl, L.; Smith, S.; Clark, K.; Bhoj, E.; Diaz, A.
10.1101/2024.10.30.621078 — neuroscience — Posted on 2024-10-31
113 Tit wit: environmental and genetic drivers of cognitive variation along an urbanization gradient
Thompson, M. J.; Gervais, L.; Bharath, D.; Caro, S. P.; Chaine, A. S.; Perrier, C.; Reale, D.; Charmantier, A.
10.1101/2024.10.30.621098 — animal behavior and cognition — Posted on 2024-10-31
114 Spatiotemporal map of the developing human reproductive tract at single-cell resolution
Lorenzi, V.; Mazzeo, C. I.; Yayon, N.; Ruiz-Morales, E. R.; Sancho-Serra, C.; Wong, F. C. K.; Mareckova, M.; Tuck, L.; Roberts, K.; Li, T.; Jacques, M.-A.; He, X.; Barker, R.; Crespo, B.; Cakir, B.; Murray, S.; Prete, M.; Gu, Y.; Kelava, I.; Garcia-Alonso, L.; Marioni, J. C.; Tormo, R. V.
10.1101/2024.10.30.621114 — developmental biology — Posted on 2024-10-31
116 Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along cochlear axis
Yan, M.; Zhang, P.; Wang, Y.; Wang, H.; Li, J.; Guo, X.; Zeng, X.; Gao, Y.; Dong, J.; Zhu, B.; Deng, D.; Ma, L.; Feng, Y.; Wu, H.-J.; Zhao, Y.; Li, J.
10.1101/2024.10.30.621022 — developmental biology — Posted on 2024-10-31
119 Sequential transcriptional programs underpin activation of quiescent hippocampal stem cells.
Rigo, P.; Ahmed-de-Prado, S.; Johnston, R. L.; Choudhury, C.; Guillemot, F.; Harris, L.
10.1101/2024.10.29.620545 — neuroscience — Posted on 2024-10-31
120 IL-17A Alters Human Cortical Development in a 3D Ex Vivo Model of Maternal Immune Activation
Assir, M. Z. K.; Yanakiev, M.; Gim, D. H.; Valkila, S. S. M.; Muscolino, P.; Fowler, P.; Berg, D. A.; Kang, E.
10.1101/2024.10.30.621011 — neuroscience — Posted on 2024-10-31
123 Distinct representations of economic variables across regions and projections of the frontal cortex
Majumdar, A.; Ashcroft, C.; Fritsche, M.; Zatka-Haas, P.; Walker, N.; Bijoch, L.; Mistry, L.; Rominto, A.; Duckworth-Essilfie, T.; Swann, J.; Molnar, Z.; Packer, A.; Butt, S.; Lak, A.
10.1101/2024.10.30.621089 — neuroscience — Posted on 2024-10-31
126 Abstract rule generalization for composing novel meaning recruits the frontoparietal control network
Zheng, X. Y.; Garvert, M. M.; den Ouden, H. E. M.; Horstman, L. I.; Richter, D.; Cools, R.
10.1101/2024.10.30.621101 — neuroscience — Posted on 2024-10-31
130 Astrocyte transcriptomic analysis identifies glypican 5 downregulation as a contributor to synaptic dysfunction in Alzheimer disease models
Salas, I. H.; Paumier, A.; Tao, T.; Derevyanko, A.; Switzler, C.; Burgado, J.; Movsesian, M.; Metanat, S.; Dawoodtabar, T.; Asbell, Q.; Fassihi, A.; Allen, N. J.
10.1101/2024.10.30.621182 — neuroscience — Posted on 2024-10-31
132 Secondary motor cortex tracks decision value and supports behavioral flexibility during non-instructed choice
Augusto, E.; Kouskoff, V.; Chenouard, N.; Giraudet, M.; Peltier, L.; de Miranda, A.; Louis, A.; Alonso, L.; Gambino, F.
10.1101/2024.10.29.620931 — neuroscience — Posted on 2024-10-31
137 Single-cell profiling of cortical tubers in tuberous sclerosis complex shows molecular structure preservation and massive reorganization of metabolism
Sorensen, F. N. F.; Petanjek, T. L.; Scheper, M.; Rydbirk, R.; Korshunova, I.; Anink, J.; Mühlebner, A.; Mills, J. D.; Petanjek, Z.; Aronica, E.; Khodosevich, K.
10.1101/2024.10.31.621014 — neuroscience — Posted on 2024-10-31
141 Monitoring the Coating of Single DNA Origami Nanostructures with a Molecular Fluorescence Lifetime Sensor
Scheckenbach, M.; Brueggenthies, G. A.; Schroeder, T.; Betuker, K.; Wassermann, L. M.; Tinnefeld, P.; Heuer-Jungemann, A.; Glembockyte, V.
10.1101/2024.10.28.620667 — biophysics — Posted on 2024-10-31
143 Improved Allele Frequencies in gnomAD through Local Ancestry Inference
Atkinson, E. G.; Kore, P.; Wilson, M.; Tiao, G.; Chao, K. R.; Darnowsky, P.; Watts, N.; Honorato-Mauer, J.; Baxter, S. M.; Genome Aggregation Database Consortium, ; Rehm, H.; Daly, M.; Karczewski, K. J.
10.1101/2024.10.30.620961 — genomics — Posted on 2024-10-31
145 Territorial behavior as a route of social microbial transmission in an asocial mammal
Petrullo, L.; Webber, Q.; Raulo, A.; Boutin, S.; Lane, J. E.; McAdam, A. G.; Dantzer, B.
10.1101/2024.10.28.620674 — ecology — Posted on 2024-10-31
147 Machine learning models reveal environmental and genetic factors associated with the plant circadian clock
Reynolds, C.; Colmer, J.; Rees, H.; Khajouei, E.; Rusholme-Pilcher, R. L.; Kudoh, H.; Dodd, A. N.; Hall, A.
10.1101/2024.10.28.620591 — plant biology — Posted on 2024-10-31
148 Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism
Kavanagh, M. E.; McLean, K. J.; Gilbert, S. H.; Amadi, C.; Snee, M.; Tunnicliffe, R. B.; Arora, K.; Boshoff, H.; Fanourakis, A.; Rebello-Lopez, M. J.; Ortega-Muro, F.; Levy, C.; Munro, A. W.; Leys, D.; Abell, C.; Coyne, A. G.
10.1101/2024.10.28.620643 — pharmacology and toxicology — Posted on 2024-10-31
151 Diffusion-based artificial genomes and their usefulness for local ancestry inference
Szatkownik, A.; Planche, L.; Demeulle, M.; Chambe, T.; Avila Arcos, M.; Huerta-Sanchez, E.; Furtlehner, C.; Charpiat, G.; Jay, F.; Yelmen, B.
10.1101/2024.10.28.620648 — bioinformatics — Posted on 2024-10-31
153 Design of Novel Dehalogenases using Protein Large Language Models
Garcia, L. N.; Nauber, W.; Dahlgren, C.; Reyes, T.; Santos, J.; Chung, R.; Kapur, M.; Barsever, M.; Thomson, M.; Lourenco, A.
10.1101/2024.10.28.620469 — bioengineering — Posted on 2024-10-31
154 Improving Accuracy of Somatic Mutation Profiling in Large Epidemiologic Studies: Addressing Cases without Matched Normal Samples
Arora, A.; Luo, L.; Kostrzewa, C. E.; Reiner, A.; Seshan, V. E.; Ernstoff, M. S.; Edmiston, S. N.; Conway, K.; Gorlov, I.; Busam, K.; Orlow, I.; Hernando, E.; Thomas, N. E.; Berwick, M.; Begg, C. B.; Shen, R.
10.1101/2024.10.28.617052 — genomics — Posted on 2024-10-31
155 A near telomere-to-telomere phased reference assembly for the male mountain gorilla
Nelson, D. R.; Muvunyi, R.; Hazzouri, K. M.; Tumushime, J.-C.; Nzayisenga, G.; Nziza, J.; Meert, W.; Karim, L.; Coppieters, W.; Munson, K. M.; Yoo, D.; Eichler, E.; Salehi-Ashtiani, K.; Twizere, J.-C.
10.1101/2024.10.28.620258 — genomics — Posted on 2024-10-31
156 Genetic diversity and population structure of pedunculate oaks (Quercus robur) in Wytham Woods
Hung, T. H.; Formaggia, E.; Morley, L.; Kirby, K.; Salguero-Gomez, R.; Sheldon, B. C.; MacKay, J. J.
10.1101/2024.10.28.619668 — genomics — Posted on 2024-10-31
158 The effects of CDC45 mutations on DNA replication and genome stability
Denkiewicz-Kruk, M.; Chaudhry, D.; Krasilia, A.; Jedrychowska, M.; Fijalkowska, I. J.; Dmowski, M.
10.1101/2024.10.28.620574 — genetics — Posted on 2024-10-31
162 Contrasting macroevolutionary patterns in the human N-glycosylation pathway
Kifer, D.; Corak, N.; Domazet-Loso, M.; Kasalo, N.; Lauc, G.; Klobucar, G.; Domazet-Loso, T.
10.1101/2024.10.30.621208 — evolutionary biology — Posted on 2024-10-31
165 A randomized controlled trial of the effectiveness of a community-based rabies vaccination strategy
Lankester, F.; Lugelo, A.; Changalucha, J.; Anderson, D.; Duamor, C. T.; Czupryna, A.; Lushasi, K.; Ferguson, E.; Swai, E. S.; Nonga, H.; Sambo, M.; Cleaveland, S.; Wyke, S.; Johnson, P. C. D.; Hampson, K.
10.1101/2024.10.28.620430 — immunology — Posted on 2024-10-31
166 Synaptic gene expression is coordinated across development by conserved chromatin regulators
Kentro, J. A.; Singh, G.; Pham, T. M.; Currie, J.; Khullar, S.; Medeiros, A. T.; Larschan, E.; O'Connor-Giles, K. M.
10.1101/2024.10.30.621128 — neuroscience — Posted on 2024-10-31
167 Mapping intratumoral myeloid-T cell interactomes at single-cell resolution reveals targets for overcoming checkpoint inhibitor resistance
Bridges, K.; Pizzurro, G. A.; Baysoy, A.; Baskaran, J. P.; Xu, Z.; Mathew, V.; Tripple, V.; LaPorte, M.; Park, K.; Damsky, W.; Kluger, H.; Fan, R.; Kaech, S. M.; Bosenberg, M. W.; Miller-Jensen, K.
10.1101/2024.10.28.620093 — systems biology — Posted on 2024-10-31
172 Disentangling the contributions of stress fibres and the unbundled actin meshwork to the anisotropy of cortical tension in response to cell shape
Fage, F.; Asnacios, S.; Pluta, A.; Richert, A.; Vias, C.; Fouchard, J.; Enslen, H.; Etienne, J.; Callan-jones, A.; THERY, M.; Pereira, D.; Asnacios, A.
10.1101/2024.10.25.620349 — biophysics — Posted on 2024-10-31
173 Small-molecule modulators of lipid raft stability and protein-raft partitioning
Stefanski, K. M.; Huang, H.; Luu, D. D.; Hutchison, J. M.; Saksena, N.; Fisch, A. J.; Hasaka, T. P.; Bauer, J. A.; Kenworthy, A. K.; Van Horn, W. D.; Sanders, C.
10.1101/2024.10.28.620521 — biophysics — Posted on 2024-10-31
180 Computational design of Bax-inhibiting peptides
Vlaar, T.; Mayer, B. M.; van der Heide, L. P.; Ilie, I. M.
10.1101/2024.10.28.617283 — bioengineering — Posted on 2024-10-31
184 Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells
Herbst, M.; Koksal, H.; Brunn, S.; Zanetti, D.; Domocos, I.; De Stefani, V.; Pereira, P.; Nater, M.; Cecconi, V.; van den Broek, M.
10.1101/2024.10.28.620471 — immunology — Posted on 2024-10-31
186 A hierarchical coordinate system for sequence memory in human entorhinal cortex.
Shpektor, A.; Bakermans, J. J. W.; Baram, A. B.; Sarnthein, J.; Ledergerber, D.; Imbach, L.; Muller-Seydlitz, E.; Barron, H. C.; Behrens, T. E. J.
10.1101/2024.10.30.620612 — neuroscience — Posted on 2024-10-31
188 The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus
Bao, H.; Wang, Y.; Li, H.; Wang, Q.; Lei, Y.; Ye, Y.; Wadood, S. F.; Zhu, H.; Staehelin, C.; Stacey, G.; Xu, S.; Cao, Y.
10.1101/2024.03.06.583716 — plant biology — Posted on 2024-10-31
189 Crystal structure of a Photosystem II-related, Manganese-binding, TPM-domain protein at a 1.6 A resolution
Vidal-Meireles, A.; Malesinski, S.; Horrenberger, Y.; Monteil, C.; Alric, J.; Siponen, M.; Johnson, X.
10.1101/2024.10.28.620569 — plant biology — Posted on 2024-10-31
190 BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma
Clark, C.; Barzegar Behrooz, A.; Da Silva Rosa, S. C.; Jacobs, J.; Weng, X.; Srivastava, A.; Vitorino, R.; Ande, S. R.; Ravandi, A.; Dhingra, S.; Pecic, S.; Miller, D.; Shojaei, S.; Ghavami, S.
10.1101/2024.08.23.609447 — cancer biology — Posted on 2024-10-31
194 CFC-seq: identification of full-length capped RNAs unveil enhancer-derived transcription
Yip, C. W.; Parr, C.; Takahashi, H.; Yasuzawa, K.; Valentine, M.; Nishiyori-Sueki, H.; Ugolini, C.; Ranzani, V.; Murata, M.; Kato, M.; Kang, W.; Yip, W. H.; Shibayama, Y.; Sim, A. D.; Chen, Y.; Shu, X.; Moody, J. D.; Umarov, R.; Chang, J.-C.; Pandolfini, L.; Kawashima, T.; Tagami, M.; Nobusada, T.; Kouno, T.; Alfonso Gonzalez, C.; Albanese, R.; Dossena, F.; Haberman, N.; Ozaki, K.; Kasukawa, T.; Lenhard, B.; Frith, M.; Bodega, B.; Nicassio, F.; Calviello, L.; Bienko, M.; Legnini, I.; Hilgers, V.; Gustincich, S.; Goeke, J.; Lecellier, C. H.; Shin, J. W.; Hon, C.-C.; Carninci, P.
10.1101/2024.10.31.620483 — genomics — Posted on 2024-10-31
196 Chemical cues from beetle larvae trigger proliferation and putative virulence gene expression of a plant pathogen
Cambon, M. C.; Thomas, G.; Caulfield, J. C.; Crampton, M.; Reed, K.; Doonan, J. M.; Hussain, U.; Denman, S.; Vuts, J.; McDonald, J. E.
10.1101/2023.11.21.568124 — ecology — Posted on 2024-10-31
199 RNPS1 in PSAP complex controls periodic pre-mRNA splicing over the cell cycle
Fukumura, K.; Masuda, A.; Takeda, J.-i.; Nagano, O.; Saya, H.; Ohno, K.; Mayeda, A.
10.1101/2023.11.20.567984 — molecular biology — Posted on 2024-10-31
201 Biosynthesis of mitis group streptococcal glycolipids and their roles in physiology and antibiotic susceptibility
Wei, Y.; Chen, G. H.; Yaqub, M.; Kim, E.; Tillett, L. E.; Joyce, L. R.; Dillon, N. A.; Palmer, K. L.; Guan, Z.
10.1101/2024.10.30.621112 — microbiology — Posted on 2024-10-31
203 Study-Phase Reinstatement
Halpern, D.; Lega, B.; Gross, R. E.; Sperling, M. R.; Wu, C.; Aronson, J. P.; Jobst, B. C.; Kahana, M. J.
10.1101/2023.10.04.560946 — neuroscience — Posted on 2024-10-31
205 Olfactory cortical outputs recruit and shape distinct brain-wide spatiotemporal networks
Ma, T.; Wang, X.; Lin, X.; Wen, J.; Xie, L.; Khong, P.-L.; Cao, P.; Wu, E. X.; Leong, A. T. L.
10.1101/2024.07.19.604242 — neuroscience — Posted on 2024-10-31
207 Nosemosis negatively affects honeybee survival: experimental and meta-analytic evidence
Ostap-Chec, M.; Cait, J.; Scott, W. R.; Arct, A.; Moron, D.; Rapacz, M.; Miler, K.
10.1101/2024.02.27.581909 — pathology — Posted on 2024-10-31
208 Decoupling individual host response and immune cell engager cytotoxic potency
Gonzalez Gutierrez, C.; Aimard, A.; Pelicot-Biarnes, M.; Kerfelec, B.; Puech, P.-H.; Robert, P.; Piazza, F.; Chames, P.; Limozin, L.
10.1101/2024.06.22.600188 — biophysics — Posted on 2024-10-31
212 Human Plasma Proteomic Profile of Clonal Hematopoiesis
Yu, Z.; Vromman, A.; Nguyen, N. Q. H.; Schuermans, A.; Rentz, T.; Vellarikkal, S. K.; Uddin, M. M.; Niroula, A.; Griffin, G.; Honigberg, M. C.; Lin, A. E.; Gibson, C. J.; Katz, D. H.; Tahir, U.; Fang, S.; Haidermota, S.; Ganesh, S.; Antoine, T.; Weinstock, J.; Austin, T. R.; Vasan, R. S.; peloso, G. M.; Hornsby, W.; Ganz, P.; Manson, J. E.; Haring, B.; Kooperberg, C. L.; Reiner, A. P.; Bis, J. C.; Psaty, B. M.; Min, Y.-I.; Correa, A.; Lange, L. A.; Post, W.; Rotter, J. I.; Rich, S. S.; Wilson, J. G.; Ebert, B. L.; Yu, B.; Ballantyne, C. M.; Coresh, J.; Sankaran, V. G.; Bick, A. G.; Jaiswal, S.
10.1101/2023.07.25.550557 — genetics — Posted on 2024-10-31
214 LoxCode in vivo clonal barcoding resolves mammalian epiblast contribution to fetal organs
Weber, T. S.; Biben, C.; Miles, D. C.; Glaser, S.; Tomei, S.; Kueh, A. J.; Pal, M.; Zhang, S.; Tam, P.; Taoudi, S.; Naik, S. H.
10.1101/2023.01.02.522501 — developmental biology — Posted on 2024-10-31
215 Single-cell transcriptomics reveal individual and synergistic effects of Trisomy 21 and GATA1s on hematopoiesis
Takasaki, K.; Wafula, E. K.; Kumar, S. S.; Smith, D.; Sit, Y. T.; Gagne, A. L.; French, D. L.; Thom, C. S.; Chou, S. T.
10.1101/2024.05.24.595827 — molecular biology — Posted on 2024-10-31
216 TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing
Pogorelyy, M. V.; Kirk, A. M.; Adhikari, S.; Minervina, A. A.; Sundararaman, B.; Vegesana, K.; Brice, D. C.; Scott, Z. B.; SJTRC Study Team, ; Thomas, P. G.
10.1101/2024.09.16.613345 — immunology — Posted on 2024-10-31
219 Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy
Creed, R. B.; Harris, S. C.; Sridhar, S.; du Lac, S.; Zee, D. S.; Dunn, F. A.; Bouvier, G.; Nelson, A. B.
10.1101/2024.09.20.614197 — neuroscience — Posted on 2024-10-31
222 Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk
Kramer, N. E.; Byun, S.; Coryell, P.; D'Costa, S.; Thulson, E.; Kim, H.; Parkus, S. M.; Bond, M. L.; Klein, E. R.; Shine, J.; Chubinskaya, S.; Love, M. I.; Mohlke, K. L.; Diekman, B. O.; Loeser, R. F.; Phanstiel, D. H.
10.1101/2024.05.05.592567 — genetics — Posted on 2024-10-31
226 Validation of Reference Genes for RT-qPCR Relative Expression Analysis in Pre-Adult Stages of Taenia solium
Castaneda, D.; Maravi, J. d. C.; Gutierrez-Loli, R.; Villar, V.; Blume La Torre, J.; Del Aguila, S. W.; Guerra-Giraldez, C.
10.1101/2022.03.22.485324 — microbiology — Posted on 2024-10-31
227 Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder
Green, N.; Gao, H.; Chu, X.; Yuan, Q.; McGuire, P.; Lai, D.; Jiang, G.; Xuei, X.; Reiter, J. L.; Stevens, J.; Sutherland, G. T.; Goate, A. M.; Pang, Z. P.; Slesinger, P.; Hart, R. P.; Tischfield, J. A.; Agrawal, A.; Wang, Y.; Duren, Z.; Edenberg, H. J.; Liu, Y.
10.1101/2024.08.02.606355 — neuroscience — Posted on 2024-10-31
228 Mapping patterns of thought onto brain activity during movie-watching
Wallace, R. S.; Mckeown, B.; Goodall-Halliwell, I.; Chitiz, L.; Forest, P.; Karapanagiotidis, T.; Mulholland, B.; Turnbull, A. G.; Vanderwal, T.; Hardikar, S.; Alam, T. G.; Bernhardt, B.; Wang, H.-T.; Strawson, W.; Milham, M.; Xu, T.; Margulies, D.; Poerio, G. L.; Jefferies, E. S.; Skipper, J. I.; Wammes, J.; Leech, R.; Smallwood, J.
10.1101/2024.01.31.578244 — neuroscience — Posted on 2024-10-31
229 Silicon Nitride Induces Osteoconduction Via Activated Mitochondrial Oxidative Phosphorylation and Neovascularization
Gonzales, W. D.; Khade, R.; Kondo, T.; Arimoto, S.; Inagaki, T.; Hokugo, A.; Kaczor-Urbanowicz, K. E.; McEntire, B.; Bock, R. M.; Ogawa, T.; Pezzotti, G.; Nishimura, I.
10.1101/2024.07.09.602787 — bioengineering — Posted on 2024-10-31
230 TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence
Kahlhofer, J.; Marchet, N.; Seifert, B.; Zubak, K.; Hotze, M.; Egger, A.-S.; Manzl, C.; Weyer, Y.; Weys, S.; Offterdinger, M.; Herzog, S.; Reiterer, V.; Kwiatkowski, M.; Wortmann, S. B.; Nemati, S.; Mayr, J. A.; Zschocke, J.; Radlinger, B.; Thedieck, K.; Huber, L. A.; Farhan, H.; de Araujo, M. E.; Kaser, S.; Scholl-Burgi, S.; Karall, D.; Teis, D.
10.1101/2024.10.29.620655 — cell biology — Posted on 2024-10-30
232 A synthetic platform for multiplex screening of cell-cell communication between soil fungi
Schiesaro, G.; Undabarrena, A.; Sorensen, M. B.; Wäneskog, M.; Jönsson, M.; Tenente, R.; Rago, D.; Deichmann, M.; Hoch-Schneider, E.; Kandasamy, V.; Özdemir, E.; Cruz-Morales, P.; Frimurer, T. M.; Clemmensen, L. K. H.; Jensen, M. K.; Jensen, E. D.
10.1101/2024.10.30.620951 — synthetic biology — Posted on 2024-10-30
233 AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic beta-solenoid structures for repeat proteins
Pratt, O. S.; Elliott, L. G.; Haon, M.; Mesdaghi, S.; Price, R. M.; Simpkin, A. J.; Rigden, D. J.; Rigden, D. J.
10.1101/2024.10.30.621056 — bioinformatics — Posted on 2024-10-30
234 Neurons and astrocytes have distinct organelle signatures and responses to stress
Rhoads, S. N.; Dong, W.; Hsu, C.-H.; Mfulama, N. R.; Ragusa, J. V.; Ye, M.; Henrie, A.; Zanellati, M. C.; Diering, G. H.; Cohen, T. J.; Cohen, S.
10.1101/2024.10.30.621066 — cell biology — Posted on 2024-10-30
236 Human spermatogenesis leads to a reduced nuclear pore structure and function
dos Santos, A.; Knowles, O.; Dendooven, T.; Hale, T.; Burt, A.; Kolata, P.; Cannone, G.; Bellini, D.; Barford, D.; Allegretti, M.
10.1101/2024.10.30.620797 — cell biology — Posted on 2024-10-30
237 ER O-glycosylation in synovial fibroblasts drives cartilage degradation
Tran, L. S.; Chia, J.; Le Guezennec, X.; Tham, K. M.; Nguyen, A. T.; Sandrin, V.; Chen, W. C.; Tan, T. L.; Sechachalam, S.; Leong, K. P.; Bard, F. A.
10.1101/2024.10.30.621134 — cell biology — Posted on 2024-10-30
241 SeqTagger, a rapid and accurate tool to demultiplex direct RNA nanopore sequencing datasets
Pryszcz, L. P.; Diensthuber, G.; Llovera, L.; Medina, R.; Delgado-Tejedor, A.; Cozzuto, L.; Ponomarenko, J.; Novoa, E. M.
10.1101/2024.10.29.620808 — genomics — Posted on 2024-10-30
242 Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors
Bamidele, N.; Andosoria, A.; Chen, Z.; Cheng, H.; Panwala, R.; Jazbec, E.; Sontheimer, E. J.
10.1101/2024.10.30.620986 — molecular biology — Posted on 2024-10-30
244 Netupitant Exhibits Potent Activity on Mycobacterium tuberculosis Persisters
Eldesouky, H. E.; Jones, R. M.; Gleason, N.; Mohammed, S.; Xing, E.; Li, P.-K.; Sherman, D. R.
10.1101/2024.10.30.620736 — microbiology — Posted on 2024-10-30
245 Dickeya ananae sp. nov., pectinolytic bacterium isolated from pineapple (Ananas comosus)
Dobhal, S.; Cotte-Pattat, N.; Arizala, D.; Sari, G. B.; Chuang, S.-C.; Alvarez, A.; Arif, M.
10.1101/2024.10.29.620964 — microbiology — Posted on 2024-10-30
246 Biosynthesis of mitis group streptococcal glycolipids and their roles in physiology and antibiotic susceptibility
Wei, Y.; Chen, G. H.; Yaqub, M.; Kim, E.; Tillett, L. E.; Joyce, L. R.; Dillon, N. A.; Palmer, K. L.; Guan, Z.
10.1101/2024.10.30.621112 — microbiology — Posted on 2024-10-30
247 Phosphate amendment drives bloom of RNA viruses after soil wet-up
Sieradzki, E. T.; Allen, G. M.; Kimbrel, J. A.; Nicol, G. W.; Hazard, C.; Nuccio, E. E.; Blazewicz, S. J.; Pett-Ridge, J.; Trubl, G.
10.1101/2024.10.30.616729 — microbiology — Posted on 2024-10-30
248 Lacticaseibacillus rhamnosus GG in a chewable colonizes the nose and facilitates local immune benefits in allergic rhinoconjunctivitis patients
De Boeck, I.; Spacova, I.; Cauwenberghs, E.; Eilers, T.; Gehrmann, T.; Van den Bossche, K.; Martens, K.; Condori-Catachura, S.; Michiels, K.; De Winter, F. H. R.; Kumar-Singh, S.; Bruffaerts, N.; Packeu, A.; Hellings, P. W.; Vroegop, A.; Van Gool, K.; Vanderveken, O. M.; Lebeer, S.
10.1101/2024.10.29.620974 — microbiology — Posted on 2024-10-30
250 Phage CRISPR-like regulatory RNAs silence bacterial adaptive and innate immunity
Liu, C.; Wang, R.; Li, Z.; Wang, W.; Yao, J.; Cheng, F.; Du, X.; Guan, L.; Mestre, M. R.; Xue, Q.; Du, J.; Xu, J.; Zhou, T.; Shu, X.; Zhao, H.; Feng, Y.; Pinilla-Redondo, R.; Li, M.
10.1101/2024.10.29.618823 — microbiology — Posted on 2024-10-30
252 Long-context Protein Language Model
Wang, Y.; Wang, Z.; Sadeh, G.; Zancato, L.; Achille, A.; Karypis, G.; Rangwala, H.
10.1101/2024.10.29.620988 — synthetic biology — Posted on 2024-10-30
253 Self-Documenting Plasmids
Peccoud, S. J.; Hernandez, S. I.; Kar, D. M.; Berezin, C.-T.; Peccoud, J.
10.1101/2024.10.29.620927 — synthetic biology — Posted on 2024-10-30
254 Site-specific quantification of the in vivo UFMylome reveals myosin modification in ALS
Blazev, R.; Zee, B. M.; Peckham, H.; Ng, Y.-K.; Lewis, C. T.; Zhang, C.; McNamara, J. W.; Goodman, C. A.; Gregorevic, P.; Ochala, J.; Steyn, F. J.; Ngo, S. T.; Stokes, M. P.; Parker, B. L.
10.1101/2024.10.30.621144 — biochemistry — Posted on 2024-10-30
255 Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases
Hoff, J. F.; Goudar, K. E.; Beer, M.; Hinchliffe, P.; Shaw, J. M.; Tooke, C. L.; Takebayashi, Y.; Mulholland, A. J.; Schofield, C. J.; Spencer, J.
10.1101/2024.10.30.621041 — biochemistry — Posted on 2024-10-30
259 The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain
Higginson, L. A.; Wang, X.; He, K.; Torstrick, M.; Kim, M.; Benayoun, B. A.; MacLean, A. L.; CHANFREAU, G. F.; Morton, D. J.
10.1101/2024.10.30.620488 — molecular biology — Posted on 2024-10-30
260 Methane production from hydrocarbons by consortia dominated by ANME archaea
Sarno, N.; Montgomery, A.; Zhuang, G.-C.; Martinez, B. R.; De Anda, V.; Joye, S. B.; Baker, B. J.
10.1101/2024.10.30.621140 — microbiology — Posted on 2024-10-30
263 Promiscuous and unbiased recombination underlies the sequence-discrete species of the SAR11 lineage in the deep ocean
Zhao, J.; Maria Pachiadaki, M.; Conrad, R.; Hatt, J.; Bristow, L.; Rodriguez-R, L.; Rossello-Mora, R.; Stewart, F. J. M.; Konstantinidis, K. T.
10.1101/2024.10.30.621061 — microbiology — Posted on 2024-10-30
266 Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas
Huang, A. Y.; Burke, K. P.; Porter, R.; Meiger, L.; Fatouros, P.; Yang, J.; Robitschek, E.; Vokes, N. I.; Ricker, C.; Rosado, V.; Tarantino, G.; Chen, J.; Aprati, T. J.; Glettig, M. C.; He, Y.; Wang, C.; Fu, D.; Ho, L.-l.; Galani, K.; Freeman, G. J.; Buchbinder, E. I.; Hodi, F. S.; Kellis, M.; Boland, G. M.; Sharpe, A. H.; Liu, D.
10.1101/2024.10.29.620300 — cancer biology — Posted on 2024-10-30
267 Markers, Mechanisms and Metrics of Biological Aging: A Scoping Review
Ziesel, A.; Reeves, J.; Mallidou, A.; Newton, L.; Rhodes, R.; Zhang, J.; Paterson, T.; Jabbari, H.
10.1101/2024.10.29.620898 — molecular biology — Posted on 2024-10-30
268 Structure elucidation, biosynthetic gene cluster distribution, and biological activities of ketomemicin analogs in Salinispora
Castro-Falcon, G.; Guillen-Matus, D.; Da Silva, E. B.; Guo, W.; Ross, A.; Serafim, M. M.; Fernandes, T. M.; Tantillo, D.; ODonoghue, A. J.; Jensen, P. R.
10.1101/2024.10.29.620863 — microbiology — Posted on 2024-10-30
272 Comparative spatiotemporal single cell transcriptomes reveal rewiring of pre-existing regulations during emergence of Kranz anatomy in C4 grasses
Zhao, C.; Yang, J.; Ni, A.-T.; Chen, H.; Su, H.; Cheng, Y.-T.; Li, X.; Zhong, L.; Fang, D.; Sun, H.-R.; Yi, J.; Wang, Y.; Wang, Y.; Lyu, M.-J. A.; Ni, X.; Chen, L.; Li, H.; Yu, G.; Wang, Y.; Chen, R.; Yu, H.; Shao, W.; Sun, H.; Bai, Y.; Li, C.; Dong, Y.; Zou, C.; Tu, X.; Ma, S.; Guo, X.; Zhang, G.; Wang, P.; Liu, H.; Wei, T.; Gu, Y.; Xu, X.; Zhu, X.-G.
10.1101/2024.10.28.620769 — plant biology — Posted on 2024-10-30
273 Exploring N6-Methyladenosine and long transcripts in glioma cells and extracellular vesicles.
Batool, S. M.; Escobedo, A. K.; Lee, H.; Khanna, P.; Haas, K. D.; Hsia, T.; Carter, B. S.; Balaj, L.
10.1101/2024.10.28.620763 — cancer biology — Posted on 2024-10-30
276 Maternal adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero
Murphy, M.; Fallahi, S.; Dumolt, J. H.; Houck, J. A.; Vaughan, O. R.; Moore, L. G.; Julian, C. G.; Rosario, F. J.; Powell, T. L.; Jansson, T.; Lorca, R. A.
10.1101/2024.09.21.612123 — developmental biology — Posted on 2024-10-30
277 Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy
Morgan, K. J.; Carley, E.; Coyne, A. N.; Rothstein, J. D.; Lusk, C. P.; King, M. C.
10.1101/2024.09.18.613744 — cell biology — Posted on 2024-10-30
280 A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics
Lu, K.-Y.; Yang, X.; Eldridge, M. J. G.; Wagner, N. J.; Hardy, B.; Axtman, M.; Rowe, S. E.; Wang, X.; Fowler, V. G.; Helaine, S.; Pearce, K. H.; Conlon, B. P.
10.1101/2024.09.30.615828 — microbiology — Posted on 2024-10-30
286 Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading.
Kennedy, D. R.; Lemiere, J.; Tan, C.; Simental, E.; Braxton, J.; Maxwell, R. A.; Amine, A. A.; Al-Sady, B.
10.1101/2024.10.25.620326 — molecular biology — Posted on 2024-10-30
287 WITHDRAWN: Ultrastructural characterization of a viral RNA and G-protein containing, membranous organelle formed in respiratory syncytial virus infected cells
Vijayakrishnan, S.; Burns, A. M.; Blanchard, E. L.; Spink, M. C.; Gilchrist, J.; Howe, A.; Darrow, M. C.; Harkiolaki, M.; Wu, C.-Y.; Dutch, R. E.; Santangelo, P.; Fearns, R.; Bhella, D.
10.1101/2022.11.28.517999 — microbiology — Posted on 2024-10-30
289 Disorganized Inhibitory Dynamics in Hippocampal area CA1 of 22q11.2 Deletion Mutant Mice
Herrlinger, S. A.; Rao, B.; Paredes, M. E. C.; Tuttman, A. L.; Arain, H.; Varol, E.; Gogos, J. A.; Losonczy, A.
10.1101/2024.04.28.591464 — neuroscience — Posted on 2024-10-30
291 Identifying sexually dimorphic circulating microRNAs in gonochoristic and hermaphroditic marine fish species.
Geffroy, B.; Camille, H.; Blondeau-Bidet, E.; Mialhe, X.; Bajek, A.; Falguiere, J.-C.; Guiguen, Y.; Bobe, J.
10.1101/2024.10.11.617774 — molecular biology — Posted on 2024-10-30
292 Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells
Adams, N. M.; Galitsyna, A.; Tiniakou, I.; Esteva, E.; Lau, C. M.; Reyes, J.; Abdennur, N.; Shkolikov, A.; Yap, G. S.; Khodadadi-Jamayran, A.; Mirny, L.; Reizis, B.
10.1101/2024.09.18.613709 — immunology — Posted on 2024-10-30
294 Markov Field network integration of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques
Wang, S.; Myers, A.; Irvine, E. B.; Wang, C.; Maiello, P.; Rodgers, M.; Tomko, J.; Kracinovsky, K.; Borish, H. J.; Chao, M. C.; Mugahid, D.; Darrah, P. A.; Seder, R. A.; Roederer, M.; Scanga, C.; Lin, P. L.; Alter, G.; Fortune, S. M.; Flynn, J. L.; Lauffenburger, D. A.
10.1101/2024.04.13.589359 — systems biology — Posted on 2024-10-30
298 Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes.
Couderc, E.; Crist, A. B.; Daron, J.; Varet, H.; Van Hout, F. A. H.; Miesen, P.; Palatini, U.; Dabo, S.; Vial, T.; LAMBRECHTS, L.; Merkling, S.
10.1101/2024.07.01.601473 — immunology — Posted on 2024-10-30
300 Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity
Bisht, A.; Pippadpally, S.; Majumder, S.; Gopi, A. T.; Das, A.; Sahi, C.; Ramaswami, M.; Kumar, V.
10.1101/2024.10.14.618171 — neuroscience — Posted on 2024-10-30
301 Cortico-thalamic communication for action coordination in a skilled motor sequence
Li, Y.; An, X.; Mulcahey, P. J.; Qian, Y.; Xu, X. H.; Zhao, S.; Mohan, H.; Suryanarayana, S. M.; Bachschmid-Romano, L.; Brunel, N.; Whishaw, I. Q.; Huang, Z. J.
10.1101/2023.10.25.563871 — neuroscience — Posted on 2024-10-30
305 Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea
Rados, T.; Leland, O.; Escudeiro, P.; Mallon, J.; Andre, K.; Caspy, I.; vonKugelgen, A.; Stolovicki, E.; Nguyen, S.; Patop, I.; Rangel, L. T.; Kadener, S.; Renner, L.; Thiel, V.; Soen, Y.; Bharat, T.; Alva, V.; Bisson, A.
10.1101/2024.10.19.619234 — cell biology — Posted on 2024-10-30
307 Systemic inflammation and lymphocyte activation precede rheumatoid arthritis
He, Z.; Glass, M. C.; Venkatesan, P.; Feser, M. L.; Lazaro, L.; Okada, L. Y.; Tran, N. T. T.; He, Y. D.; Rachid Zaim, S.; Bennett, C. E.; Ravisankar, P.; Dornisch, E. M.; Arishi, N. A.; Asamoah, A. G.; Barzideh, S.; Becker, L. A.; Bemis, E. A.; Buckner, J. H.; Collora, C. E.; Criley, M. A. L.; Demoruelle, M. K.; Fleischer, C. L.; Garber, J.; Genge, P. C.; Gong, Q.; Graybuck, L. T.; Gustafson, C. E.; Hattel, B. C.; Hernandez, V.; Heubeck, A. T.; Kawelo, E. K.; Krishnan, U.; Kuan, E. L.; Kuhn, K. A.; LaFrance, C. M.; Lee, K. J.; Li, R.; Lord, C.; Mettey, R. R.; Moss, L.; Musgrove, B.; Nguyen, K.
10.1101/2024.10.25.620344 — immunology — Posted on 2024-10-30
308 A Novel Early Onset Spinocerebellar Ataxia 13 BAC Mouse Model with Cerebellar Hypoplasia, Tremor, and Ataxic Gait
Yin, J.; Nick, J. A.; Khare, S.; Kloefkorn, H. E.; Gao, M.; Wu, M.; White, J.; Resnick, J.; Allen, K. D.; Nick, H. S.; waters, M. F.
10.1101/2024.10.28.620097 — neuroscience — Posted on 2024-10-30
309 chrna3 modulates alcohol response in zebrafish
Raine, J.; Kibat, C.; Banerjee, T. D.; Monteiro, A.; Mathuru, A.
10.1101/2024.08.22.607435 — neuroscience — Posted on 2024-10-30
310 Dual transcranial electromagnetic stimulation of the precuneus-hippocampus network boosts human long-term memory
Borghi, I.; Mencarelli, L.; Maiella, M.; Casula, E. P.; Ferraresi, M.; Candeo, F.; Savastano, E.; Assogna, M.; Bonni, S.; Koch, G.
10.1101/2024.10.25.620008 — neuroscience — Posted on 2024-10-30
311 Introgression of the sunflower HaHB4 gene in modern wheat: An advancement in resilience to deal with climate change
Ayala, F.; Curin, F.; Díaz-Zorita, M.; Murguía, J.; Montero-Bulacio, E.; Portapila, M.; Otegui, M. E.; Chan, R. L.; González, F. G.
10.1101/2024.10.26.620406 — plant biology — Posted on 2024-10-30
312 Association of the benzoxazinoid pathway with boron homeostasis in maize
Chu, L.; Shrestha, V.; Schäfer, C. C.; Niedens, J.; Meyer, G. W.; Darnell, Z.; Kling, T.; Dürr-Mayer, T.; Abramov, A.; Frey, M.; Jessen, H. J.; Schaaf, G.; Hochholdinger, F.; Nowak-Krol, A.; McSteen, P.; Angelovici, R.; Matthes, M. S.
10.1101/2024.10.25.620361 — plant biology — Posted on 2024-10-30
313 Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during β3-adrenergic stimulation in mice
Martin, C. M.; Polizzi, A.; Alquier-Bacquie, V.; Huillet, M.; Rives, C.; Dauriat, C.; Bruse, J.; Melin, V.; Naylies, C.; Lippi, Y.; Lasserre, F.; Wan, J.; Flores-Flores, R.; Bertrand-Michel, J.; Blas-Y-Estrada, F.; Rousseau-Bacquie, E.; Levade, T.; Remignon, H.; Langin, D.; Mouisel, E.; Loterzstajn, S.; Chassaing, B.; Gamet-Payrastre, L.; Guillou, H.; Ellero-Simatos, S.; Fougerat, A.; Loiseau, N.
10.1101/2024.10.24.619974 — physiology — Posted on 2024-10-30
314 PET microplastics increase the risk of insulin resistance and pancreatitis
Mierzejewski, K.; Kurzynska, A.; Golubska, M.; Gałecka, I.; Całka, J.; Bogacka, I.
10.1101/2024.10.25.620380 — physiology — Posted on 2024-10-30
316 Impacts of Cell Ranger versions on Chromium gene expression data
Abugessaisa, I.; Hasegawa, A.; Walker, S.; Katayama, S.; Kere, J.; Kasukawa, T.
10.1101/2024.08.10.607413 — bioinformatics — Posted on 2024-10-30
318 Leukocytes use endothelial membrane tunnels to extravasate the vasculature
van der Meer, W.; van Steen, A. C. I.; Mahlandt, E.; Rolas, L.; Wang, H.; Arts, J.; Kempers, L.; Gronloh, M.; Schoon, R. M.; Driessen, A.; van Rijssel, J.; Klaassen, I.; Schlingemann, R. O.; Manavski, Y.; Hoogenboezem, M.; Boon, R. A.; Khuon, S.; Wait, E.; Heddleston, J.; Chew, T.-L.; Nolte, M. A.; Nourshargh, S.; Goedhart, J.; van Buul, J. D.
10.1101/2024.10.28.620560 — cell biology — Posted on 2024-10-30
319 Skin bacterial community dynamics of hands and forearms before and after military field exercise
Glenna, S.; Birkeland, E.; Orr, R. J. S.; Gilfillan, G.; Dalland, M.; Okstad, O. A.; Voie, O. A.; Rounge, T. B.
10.1101/2024.10.29.620909 — microbiology — Posted on 2024-10-30
320 High-resolution perfusion imaging in rodents using pCASL at 9.4 T
Pires Monteiro, S.; Hirschler, L.; Barbier, E.; Figueiredo, P.; Shemesh, N.
10.1101/2024.03.07.583839 — neuroscience — Posted on 2024-10-30
325 Phylogenetic mapping of sleep loss in wild-caught cavefish
North, O.; Maza-Castaneda, L. C.; Manning, A. E.; Rastogi, A.; Gluesenkamp, A.; Gluesenkamp, L.; Swanson, N.; Hernandez-Lozano, J.; Garduno-Sanchez, M.; Diaz-Cruz, J. A.; Kowalko, J. E.; McGaugh, S. E.; Keene, A. C.; Ornelas-Garcia, P.
10.1101/2024.10.29.619241 — evolutionary biology — Posted on 2024-10-30
326 Exploring the adhesion properties of extracellular vesicles for functional assays
Pachane, B. C.; Carlson, B.; Queen, S.; Selistre-de-Araujo, H. S.; Witwer, K. W.
10.1101/2024.10.28.620659 — cell biology — Posted on 2024-10-30
331 New proteomic signature in circulating extracellular vesicles from tumor-draining vein of lung adenocarcinomas patients
Tricard, J.; Durand, S.; Gateau, A.; Negroni, L.; Chaunavel, A.; Bertin, F.; Conti, M.; AKIL, H.; Lalloue, F.
10.1101/2024.10.28.620567 — cancer biology — Posted on 2024-10-30
337 De novo annotation of the wheat pangenome reveals complexity and diversity of the hexaploid wheat pan-transcriptome
White, B.; LUX, T.; Rusholme-Pilcher, R.; Juhasz, A.; Kaithakottil, G.; Duncan, S.; Simmonds, J.; Rees, H.; Wright, J.; Colmer, J.; Ward, S.; joynson, R.; Coombes, B.; Irish, N.; Henderson, S.; Baker, T.; Chapman, H.; Catchpole, L.; Gharbi, K.; Okada, M.; Handa, H.; Nasuda, S.; Shimizu, K.; Gundlach, H.; Lang, D.; Naamati, G.; Legg, E.; Bharti, A.; Colgrave, M.; Haerty, W. `; Uauy, C. `; Swarbreck, D.; Borrill, P.; Poland, J.; Krattinger, S.; Stein, N.; Mayer, K. F. X.; Pozniak, C.; Spannagl, M.; Hall, A.
10.1101/2024.01.09.574802 — genomics — Posted on 2024-10-30
339 Clathrin-independent endocytosis and retrograde transport in cancer cells promote cytotoxic CD8 T cell activation
Xu, S.; Buridant, A.; Hirsch, T.; Shafaq-Zadah, M.; Dransart, E.; Ledoux, B.; Johannes, L.; van der Bruggen, P.; Morsomme, P.; Renard, H.-F.
10.1101/2024.10.28.620627 — cell biology — Posted on 2024-10-30
341 Navigated range expansion promotes migratory culling
Zhang, Y.; Hu, Q.; Su, Y.; Chu, P.; Wei, T.; Li, X.; Liu, C.; Fu, X.
10.1101/2024.03.09.584265 — systems biology — Posted on 2024-10-30
347 Transcriptional profiling of the cortico-accumbal pathway reveals sex-specific alterations underlying stress susceptibility
Pessoni, A. M.; Blanc-Arabe, L.; Pancotti, L.; Mansouri, S.; D'Angelo, M.; Huot, K.; Rivera, A. M.; Peralta, M.; Zhao, C.; Leboulleux, Q.; Levesque, M.; Proulx, C. D.; Labonte, B.
10.1101/2024.10.29.620955 — neuroscience — Posted on 2024-10-29
348 Shared Transcriptomic Signatures Reveal Synaptic Pruning as a Link Between Alzheimer's Disease and Epilepsy
Li, H.; Li, J.; Chen, M.; Liu, X.; Sun, Y.; Wu, J.; Lin, B.; Chen, S.; Deng, Z.; Hong, M.; Wei, N.-L.; Ji, X.
10.1101/2024.10.28.618752 — bioinformatics — Posted on 2024-10-29
349 UniScore, a unified and universal measure for peptide identification by multiple search engines
Tabata, T.; Yoshizawa, A. C.; Ogata, K.; Chang, C.-H.; Araki, N.; Sugiyama, N.; Ishihama, Y.
10.1101/2024.10.09.617445 — bioinformatics — Posted on 2024-10-29
350 Investigating the effects of prednisolone on behavior in mouse models of Duchenne muscular dystrophy
Verhaeg, M.; van de Vijver, D.; de Winter, C. L. T.; van der Pijl, E. M.; Mastenbroek, L. J. M.; Leka, U.; Stan, T. L.; van Putten, M.
10.1101/2024.10.29.620838 — animal behavior and cognition — Posted on 2024-10-29
352 DetectEV: a functional enzymatic assays to assess integrity and bioactivity of extracellular vesicles
Adamo, G.; Picciotto, S.; Gargano, P.; Paterna, A.; Raccosta, S.; Rao, E.; Romancino, D. P.; Ghersi, G.; Manno, M.; Salamone, M.; Bongiovanni, A.
10.1101/2023.10.24.563745 — cell biology — Posted on 2024-10-29
355 A co-transcriptional mechanism for tightly controlling RNA homeostasis in yeast
Esteban-Serna, S.; Widen, T.; Gwynne, M.; Farquhar, I.; Duchen, M.; Swain, P. S.; Granneman, S.
10.1101/2024.10.29.620883 — molecular biology — Posted on 2024-10-29
358 Structure, dynamics and evolution of the Candida albicans multi-drug resistance ABC transporter CDR1
Shin, J.; Jin, R.; Gall, B.; Jobichen, C.; Jackson, C. J.; Rug, M.; Corry, B.; Brock, J.
10.1101/2024.10.28.620768 — microbiology — Posted on 2024-10-29
359 Comparative study on the virulence of mycobacteriophages
Rubino, I.; Guerrero-Bustamante, C. A.; Harrison, M.; Co, S.; Tetreau, I.; Ordoubadi, M.; Larsen, S. E.; Coler, R. N.; Vehring, R.; Hatfull, G. E.; Sauvageau, D.
10.1101/2024.10.23.619922 — microbiology — Posted on 2024-10-29
362 Ninjurin-1 mediated plasma membrane rupture is a two-step process requiring cell swelling
Hartenian, E.; Bernard, E. M.; Ammirati, G.; Monnier, S.; Leloup, H. B.; Agustoni, M.; Bissegger, L.; Santos, J. C.; Mari, S.; Sieben, C.; Petrilli, V.; Müller, D.; Broz, P.
10.1101/2024.10.29.620849 — immunology — Posted on 2024-10-29
364 A Surface-based deep learning approach for cortical shape analysis
Im, Y.; Zhao, Y.; Gutman, B. A.; Thomopoulos, S. I.; Haddad, E.; Zhu, A. H.; Jahanshad, N.; Thompson, P. M.; Ching, C. R. K.
10.1101/2024.10.29.620757 — neuroscience — Posted on 2024-10-29
365 SCAD Delivery Platform: A Novel Approach for Efficient CNS and Extrahepatic Oligonucleotide Therapeutics
Kang, M.; Lin, W.-H.; Xu, F.; Zhou, X.; Si, C.; Liu, K.; Dai, J.; He, J.; Schacht, I.; Li, Y.; Gan, Z.; Li, L.-C.
10.1101/2024.10.29.620792 — neuroscience — Posted on 2024-10-29
367 Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system
Duplaa, C.; Delobel, V.; Boulestreau, R.; Rubin, S.; Vaurs, J.; Jaspard-Vinassa, B.; Busson, M.; Combrouze, C.; Proust, C.; Morel, J.-L.; Bontempi, B.; Mishra, A.; Debette, S.; Couffinhal, T.; Peghaire, C.
10.1101/2024.10.08.616723 — neuroscience — Posted on 2024-10-29
368 Sculpting New Visual Categories into the Human Brain
Iordan, C. R.; Ritvo, V. J. H.; Norman, K. A.; Turk-Browne, N. B.; Cohen, J. D.
10.1101/2020.10.14.339853 — neuroscience — Posted on 2024-10-29
369 Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues
Su, L.; Souaibou, Y.; Hotel, L.; Jacob, C.; Grun, P.; Shi, Y.-N.; Chateau, A.; Pinel, S.; Bode, H. B.; Aigle, B.; Weissman, K. J.
10.1101/2024.10.29.620781 — synthetic biology — Posted on 2024-10-29
370 Host genotype shapes root mycobiota in durum wheat
TRINQUIER, M.; COLOMBO, M.; FREVILLE, H.; JACQUES, D.; ROCHER, A.; LEFEBVRE, B.; ROUX, C.
10.1101/2024.10.27.616629 — plant biology — Posted on 2024-10-29
371 Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting
Ponte, M. E.; Prom, J. C.; Newcomb, M. A.; Jordan, A. B.; Comfort, L. L.; Hu, J.; Puchalska, P.; Geisler, C. E.; Hayes, M. R.; Morris, E. M.
10.1101/2024.10.24.620086 — physiology — Posted on 2024-10-29
372 DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency
Koehnke, T.; Karigane, D.; Hilgart, E.; Fan, A. C.; Kayamori, K.; Miyauchi, M.; Collins, C. T.; Suchy, F. P.; Rangavajhula, A.; Feng, Y.; Nakauchi, Y.; Martinez-Montes, E.; Fowler, J.; Loh, K. M.; Nakauchi, H.; Koldobskiy, M. A.; Feinberg, A. P.; Majeti, R.
10.1101/2024.10.26.620318 — cancer biology — Posted on 2024-10-29
373 Generative Models Validation via Manifold Recapitulation Analysis
Lazzaro, N.; Leonardi, G.; Marchesi, R.; Datres, M.; Saiani, A.; Tessadori, J.; Granados, A.; Henriksson, J.; Chierici, M.; Jurman, G.; Sales, G.; Tebaldi, T.
10.1101/2024.10.23.619602 — bioinformatics — Posted on 2024-10-29
376 Directed evolution of the multicopper oxidase laccase for cell surface proximity labeling and electron microscopy
Lee, S.-Y.; Roh, H.; Gonzalez-Perez, D.; Mackey, M. R.; Kim, K.-Y.; Hoces, D.; McLaughlin, C.; Adams, S. R.; Nguyen, K.; Luginbuhl, D. J.; Luo, L.; Udeshi, N.; Carr, S. A.; Hernandez-Lopez, R. A.; Ellisman, M.; Alcalde, M.; Ting, A. Y.
10.1101/2024.10.29.620861 — biochemistry — Posted on 2024-10-29
379 Pervasive fitness trade-offs revealed by rapid adaptation in large experimental populations of Drosophila melanogaster
Bitter, M. C.; Greenblum, S.; Rajpurohit, S.; Bergland, A. O.; Hemker, J. A.; Betancourt, N. J.; Tilk, S.; Berardi, S.; Oken, H.; Schmidt, P.; Petrov, D.
10.1101/2024.10.28.620721 — evolutionary biology — Posted on 2024-10-29
380 Residence-colonization trade-off and niche differentiation enable the coexistence of Escherichia coli phylogroups in healthy humans
Morel-Journel, T.; Lehtinen, S.; Cotto, O.; Amia, R.; Dion, S.; Figueroa, C.; Martinson, J.; Ralaimazava, P.; Clermont, O.; Duval, X.; Nowrouzian, F. L.; Walk, S.; Denamur, E.; Blanquart, F.
10.1101/2023.08.10.552787 — evolutionary biology — Posted on 2024-10-29
381 GSK3 inhibition ameliorates the abnormal contractility of Newfoundland ACM patient iPSC-cardiomyocytes
Noort, R. J.; Salman, W.; Fuchs, C.; Braun, U.; Pace, D.; Hodgkinson, K.; Esseltine, J. L.
10.1101/2024.02.06.579108 — cell biology — Posted on 2024-10-29
382 Structural insights into maturation and translationof a plant mitoribosome
Skaltsogiannis, V.; Nguyen, T.-T.; Corre, N.; Pflieger, D.; Blevins, T.; Hashem, Y.; Giege, P.; Waltz, F.
10.1101/2024.10.28.620559 — molecular biology — Posted on 2024-10-29
384 12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice
Nargis, T.; Muralidharan, C.; Enriquez, J. R.; Wang, J. E.; Kaylan, K.; Chakraborty, A.; Pratuagntham, S.; Figatner, K.; Nelson, J. B.; May, S. C.; Nadler, J. L.; Boxer, M. B.; Maloney, D. J.; Tersey, S. A.; Mirmira, R. G.
10.1101/2024.07.28.604986 — molecular biology — Posted on 2024-10-29
385 Replication Kinetics, Pathogenicity and Virus-induced Cellular Responses of Cattle-origin Influenza A(H5N1) Isolates from Texas, United States
Mostafa, A.; Barre, R. S.; Guardia, A. A.; Escobedo, R. A.; Shivanna, V.; Rothan, H.; Castro, E. M.; Ma, Y.; Cupic, A.; Jackson, N.; Bayoumi, M.; Torrelles, J. B.; Ye, C.; Garcia-Sastre, A.; Martinez-Sobrido, L.
10.1101/2024.10.29.620905 — microbiology — Posted on 2024-10-29
386 Identification of a large cohort of Enterobacter jumbo phages with broad host ranges across pathogenic Gammaproteobacteria
Kanhirun, N.; Blanc, A.; Aindow, A.; You, M.; Antani, J. D.; Ghatbale, P.; Leonard, J.; Garcia, A. G.; Nghiem, K.; Whiteson, K.; Schooley, R.; Turner, P.; Pogliano, J.; Guemes, A. G. C.; Pride, D. T.
10.1101/2024.10.29.620934 — microbiology — Posted on 2024-10-29
387 Antibiotic lethality dictates mycobacterial infection outcomes
Jovanovic, A.; Bright, F. K.; Sadeghi, A.; Wicki, B.; Muniz, S. E. C.; Toprak, S.; Sauteur, L.; Rodoni, A.; Wust, A.; Lupien, A.; Borrell, S.; Grogono, D. M.; Wheeler, N.; Dehio, P.; Nemeth, J.; Pargger, H.; Thomson, R.; Bell, S. C.; Gagneux, S.; Bryant, J. M.; Peng, T.; Diacon, A.; Floto, R. A.; Abanto, M.; Boeck, L.
10.1101/2024.10.29.619904 — microbiology — Posted on 2024-10-29
388 Age, Sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model.
Nguyen, H. V. M.; Cabello, E.; Dyer, D.; Fender, C.; Garcia-Jaramillo, M.; Hord, N.; Austad, S.; Richardson, A.; Unnikrishnan, A.
10.1101/2024.10.28.620746 — microbiology — Posted on 2024-10-29
390 Automated web-based typing of Clostridioides difficile ribotypes via MALDI-TOF MS
Sanchez-Blazquez, M.; Guerrero-Lopez, A.; Candela, A.; Belenguer-Llorens, A.; Moreno, J. M.; Sevilla Salcedo, C.; Sanchez-Cueto, M.; Arroyo, M. J.; Gutierrez-Pareja, M.; Gomez-Verdejo, V.; Olmos, P. M.; Mancera, L.; Munoz, P.; Marin, M.; Alcala, L.; Rodriguez-Temporal, D.; Rodriguez Sanchez, B.
10.1101/2024.01.24.576988 — microbiology — Posted on 2024-10-29
392 Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology
Boucher, M.; Banerjee, S.; Joshi, M.; Wei, A.; Huang, M.; Lei, S.; Ciranni, M.; Condon, A.; Langen, A.; Goddard, T.; Caradonna, I.; Goranov, A.; Homer, C.; Mortensen, Y.; Petnic, S.; Reilly, M.; Xiong, Y.; Susa, K.; Pastore, V. P.; Zaro, B.; Madhani, H.
10.1101/2024.10.22.619677 — microbiology — Posted on 2024-10-29
394 Evaluating permutation-based inference for partial least squares analysis of neuroimaging data
Danyluik, M.; Zeighami, Y.; Mukora, A.; Lepage, M.; Shah, J.; Joober, R.; Misic, B.; Iturria-Medina, Y.; Chakravarty, M.
10.1101/2024.08.02.606412 — neuroscience — Posted on 2024-10-29
395 A split-GAL4 driver line resource for Drosophila neuron types
Meissner, G. W.; Vannan, A.; Jeter, J.; Close, K.; DePasquale, G. M.; Dorman, Z.; Forster, K.; Beringer, J. A.; Gibney, T. V.; Hausenfluck, J. H.; He, Y.; Henderson, K.; Johnson, L.; Johnston, R. M.; Ihrke, G.; Iyer, N.; Lazarus, R.; Lee, K.; Li, H.-H.; Liaw, H.-P.; Melton, B.; Miller, S.; Motaher, R.; Novak, A.; Ogundeyi, O.; Petruncio, A.; Price, J.; Protopapas, S.; Tae, S.; Taylor, J.; Vorimo, R.; Yarbrough, B.; Zeng, K. X.; Zugates, C. T.; Dionne, H.; Angstadt, C.; Ashley, K.; Cavallaro, A.; Dang, T.; Gonzalez, G. A.; Hibbard, K. L.; Huang, C.; Kao, J.-C.; Laverty, T.; Mercer, M.; Perez, B
10.1101/2024.01.09.574419 — neuroscience — Posted on 2024-10-29
396 Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition
Zhang, T.; Shin, S.; McCrimmon, C.; Theocharous, M.; Schittenhelm, R. B.; Jarde, T.; Daly, R. J.; Nguyen, L. K.
10.1101/2024.10.27.620536 — cancer biology — Posted on 2024-10-29
400 Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomycete.
Sweeney, D.; Bogdanov, A.; Chase, A. B.; Castro-Falcon, G.; Trinidad-Javier, A.; Dahesh, S.; Nizet, V.; Jensen, P. R.
10.1101/2024.10.29.620887 — biochemistry — Posted on 2024-10-29
401 Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing
Robinson, J. W.; Bechard, A. T.; Evans, M. R.; Mosuro, K.; Isaacson, J. R.; Pillay, S.; Lin, D. S.; Sahota, A.; de Belle, J. N.; Robinson, G. I.; Strong, M. J.; Simon, A. F.
10.1101/2024.10.28.620699 — animal behavior and cognition — Posted on 2024-10-29
404 Mechanochemical Patterning Localizes the Organizer of a Luminal Epithelium
Weevers, S. L.; Falconer, A. D.; Mercker, M.; Sadeghi, H.; Ferenc, J.; Ott, A.; Oelz, D. B.; Marciniak-Czochra, A.; Tsiairis, C. D.
10.1101/2024.10.29.620841 — developmental biology — Posted on 2024-10-29
405 Identification of a series of pyrrolo-pyrimidine based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication
Pfannenstiel, J. J.; Duong, M. T. H.; Cluff, D.; Sherrill, L.; Colquhoun, I.; Cadoux, G.; Thorne, D.; Paakkonen, J.; Schemmel, N. F.; O'Connor, J. J.; Saenjamsai, P.; Feng, M.; Hageman, M.; Johnson, D. K.; Roy, A.; Lehtio, L.; Ferraris, D. V.; Fehr, A. R.
10.1101/2024.10.28.620664 — microbiology — Posted on 2024-10-29
407 Telmisartan impedes JEV infection predominately via AT1/PPARγ axis
Datey, A.; Chatterjee, S.; Ghosh, S.; Kumar, P. S.; De, S.; Ghorai, U.; Subudhi, B. B.; Chattopadhyay, S.
10.1101/2024.10.29.620930 — microbiology — Posted on 2024-10-29
408 The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension
Evans, S. L.; Peretiazhko, I.; Karnani, S. Y.; Marmont, L. S.; Wheeler, J. H. R.; Tseng, B. S.; Durham, W. M.; Whitney, J.; Bergeron, J. R.
10.1101/2024.10.29.620805 — microbiology — Posted on 2024-10-29
409 Essential role of Hepcidin in host resistance to disseminated candidiasis
Arekar, T.; Katikaneni, D.; Kasem, S.; Desai, D.; Acharya, T.; Cole, A.; Khodayari, N.; Vaulont, S.; Hube, B.; Nemeth, E.; Drakesmith, H.; Lionakis, M. S.; Mehrad, B.; Scindia, Y.
10.1101/2024.10.29.620511 — microbiology — Posted on 2024-10-29
413 Overcoming Challenges of Reproducibility and Variability for the Clostridioides difficile typification
Bravo-Anton, L.; Guerrero-Lopez, A.; Sevilla-Salcedo, C.; Blazquez-Sanchez, M.; Rodriguez-Temporal, D.; Rodriguez-Sanchez, B.; Gomez-Verdejo, V.
10.1101/2024.10.29.620907 — microbiology — Posted on 2024-10-29
414 Alternate routes to acetate tolerance lead to varied isoprenol production from mixed carbon sources in Pseudomonas putida
de Siqueira, G. M. V.; Srinivasan, A.; Chen, Y.; Gin, J. W.; Petzold, C. J.; Lee, T. S.; Guazzaroni, M.-E.; Eng, T.; Mukhopadhyay, A.
10.1101/2024.10.29.620962 — microbiology — Posted on 2024-10-29
415 Unveiling Humoral and Cellular Immune Responses to SARS-CoV-2 in Head and Neck Cancer: A Comparative Study of Vaccination and Natural Infection in Romania
Marutescu, L.; Enea, A.; Antoniadis, N.-M.; Neculae, M.; Costea, D. A.; Popa, M.; Dragu, E.; Codrici, E.; Ristoiu, V.; Galateanu, B.; Hudita, A.; Pircalabioru, G. G.; Filali-Mouhim, A.; Lazar, V.; Chifiriuc, C.; Grigore, R.; Ancuta, P.
10.1101/2024.10.27.620493 — immunology — Posted on 2024-10-29
418 Transcranial Brain-Wide Functional Ultrasound and Ultrasound Localization Microscopy in Mice using Multilinear Probes
Vert, M.; Zhang, G.; Bertolo, A.; Ialy-Radio, N.; Pezet, S.; Osmanski, B.; Deffieux, T.; Nouhoum, M.; Tanter, M.
10.1101/2024.10.29.620796 — neuroscience — Posted on 2024-10-29
419 An fMRI-based Approach for Measuring Contrast Sensitivity Across the Visual Field in Visual Cortex
Chow-Wing-Bom, H. T.; Lisi, M.; Benson, N. C.; Lygo-Frett, F.; Yu-Wai-Man, P.; Dick, F.; Maimon-Mor, R. O.; Dekker, T. M.
10.1101/2024.10.29.619403 — neuroscience — Posted on 2024-10-29
422 Selective breeding for determinacy and photoperiod sensitivity in common bean (Phaseolus vulgaris L.)
Denning-James, K.; Chater, C.; Cortes, A. J.; Blair, M. W.; Pelaez, D.; Hall, A.; De Vega, J. J.
10.1101/2024.10.27.620491 — plant biology — Posted on 2024-10-29
424 Ice and air: Visualisation of freeze-thaw embolism and freezing spread in young L. tulipifera leaves
Johnson, K. M.; Scherer, M.; Gerber, D.; Style, R. W.; Dufresne, E. R.; Brodersen, C. R.
10.1101/2024.10.26.620221 — physiology — Posted on 2024-10-29
425 Chitinase-1 inhibition reverses metabolic dysregulation and restores homeostasis in MASH animal models
Drzewicka, K.; Gluchowska, K.; Mlacki, M.; Hofman, B.; Tuszynska, I.; Ryan, T.; Piwowar, K.; Wilczynski, B.; Dymkowska, D.; Dymek, B.; Rejczak, T.; Lisiecki, K.; Golebiowski, A.; Jagielski, A.; Muchowicz, A.; Ryan, D. G.; Zablocki, K. O.; O'Neil, L.; Zaslona, Z.
10.1101/2024.10.27.620490 — pharmacology and toxicology — Posted on 2024-10-29
433 Dynamic Kidney Organoid Microphysiological Analysis Platform
Hong, S.; Song, M.; Miyoshi, T.; Morizane, R.; Bonventre, J. V.; Lee, L. P.
10.1101/2024.10.27.620552 — bioengineering — Posted on 2024-10-29
435 Exploring The Genome of The Oribatid Mite, Oppia Nitens: Environmental Stress Response and Toxicity Adaptation
Adedokun, A. A.; Fajana, H. O.; Jegede, O. O.; Hammond, A. S.; Smith, D. D. N.; Kvas, S.; Hewavithana, T.; Jin, L.; Princz, J.; Siciliano, S. D.
10.1101/2024.10.27.619232 — genomics — Posted on 2024-10-29
436 Genomic Insights Guiding Personalized First-Line Immunotherapy Response in Lung and Bladder Tumors
Brea-Iglesias, J.; Gallardo-Gomez, M.; Oitaben, A.; Lazaro-Quintela, M. E.; Leon, L.; Alves, J. M.; Juaneda-Magdalena, L.; Garcia-Benito, C.; Abdulkader, I.; Muinelo, L.; Paramio, J. M.; Martinez-Fernandez, M.
10.1101/2024.10.25.620156 — genomics — Posted on 2024-10-29
438 The Oscarella sponges genus: a hidden yet colorful diversity
Guiollot, E.; Guillemain, D.; Renard, E.; Borchiellini, C.; Schenkelaars, Q.
10.1101/2024.10.26.620226 — evolutionary biology — Posted on 2024-10-29
439 Directing cellular transitions on gene graph-enhanced cell state manifold
Wang, T.; Pan, Y.; Ju, F.; Zheng, S.; Liu, C.; Min, Y.; Liu, X.; Xia, H.; Liu, G.; Liu, H.; Deng, P.
10.1101/2024.10.27.620174 — cell biology — Posted on 2024-10-29
441 Secreted phospholipase PLA2G12A-driven lysophospholipid signaling via lipolytic modification of extracellular vesicles facilitates pathogenic Th17 differentiation
Mochizuki, C.; Taketomi, Y.; Irie, A.; Kano, K.; Nagasaki, Y.; Miki, Y.; Ono, T.; Nishito, Y.; Nakajima, T.; Tomabechi, Y.; Hanada, K.; Shirouzu, M.; Watanabe, T.; Hata, K.; Izumi, Y.; Bamba, T.; Chun, J.; Kudo, K.; Kotani, A.; Endo, Y.; Aoki, J.; Murakami, M.
10.1101/2024.10.27.620543 — immunology — Posted on 2024-10-29
444 Benchmarking unsupervised methods for inferring TCR specificity
Jouannet, C.; Vantomme, H.; Klatzmann, D.; Mariotti-Ferrandiz, E.
10.1101/2024.10.26.620398 — immunology — Posted on 2024-10-29
450 A Nostalgia Brain-Music Interface for Enhancing Nostalgia, Well-Being, and Memory Vividness in Young and Elderly Individuals
Sakakibara, Y.; Kusutomi, T.; Kondoh, S.; Etani, T.; Shimada, S.; Imamura, Y.; Naruse, Y.; Fujii, S.; Ibaraki, T.
10.1101/2024.10.29.620793 — neuroscience — Posted on 2024-10-29
452 Somatomotor disconnection links sleep duration with socioeconomic context, screen time, cognition, and psychopathology
Michael, C.; Taxali, A.; Angstadt, M.; McCurry, K. L.; Weigard, A.; Kardan, O.; Molloy, F.; Toda-Thorne, K. L.; Burchell, L.; Dziubinski, M.; Choi, J.; Vandersluis, M.; Hyde, L. W.; Heitzeg, M. M.; Sripada, C.
10.1101/2024.10.29.620865 — neuroscience — Posted on 2024-10-29
454 Aluminium induces suberin biosynthesis in barley roots via ABA
Meng, H.; Zhang, Q.; Kreszies, T.; Acosta, I. F.; Schreiber, L.
10.1101/2024.10.27.620472 — plant biology — Posted on 2024-10-29
457 The plastid-encoded RNA polymerase structures a logistic chain for light-induced photosynthesis
Gillet, F.-X.; Effantin, G.; Freiherr von Scholley, G. L.; Brugiere, S.; Turquand, M.; Pasha, N.; Fenel, D.; Vallet, A.; Coute, Y.; Cobessi, D.; Blanvillain, R.
10.1101/2024.10.25.620210 — plant biology — Posted on 2024-10-29
458 Obesity induces phenotypic switching of gastric smooth muscle cells through the activation of the PPARD/PDK4/ANGPTL4 pathway
Dekkar, S.; Mahloul, K.; Falco, A.; Konate, K.; Pisteur, R.; Maurel, S.; Maimoun, L.; Chauvet, N.; Boisguerin, P.; Nocca, D.; Sultan, A.; Pallot, F.; Walther, G.; Cenac, N.; Breuker, C.; Faure, S.; de Santa Barbara, P.
10.1101/2024.10.27.620509 — physiology — Posted on 2024-10-29
460 A multi-subunit autophagic capture complex facilitates degradation of ER stalled MHC-I in pancreatic cancer.
Berquez, M.; Li, A. L.; Luy, M. A.; Venida, A. C.; O'Loughlin, T.; Rademaker, G.; Barpanda, A.; Hu, J.; Yano, J.; Wiita, A.; Gilbert, L. A.; Bruno, P. M.; Perera, R. M.
10.1101/2024.10.27.620516 — cancer biology — Posted on 2024-10-29
461 Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm
Vasileva, E.; Arata, C. E.; Luo, Y.; Burgos, R.; Crump, J. G.; Amatruda, J. F.
10.1101/2024.10.27.620438 — cancer biology — Posted on 2024-10-29
462 Fibroblast activation protein defines aggressive EMT-associated cancer cell state and prognosis in localized ccRCC
Pellinen, T.; Luomala, L.; Mattila, K. E.; Hemmes, A.; Valimaki, K.; Bruck, O.; Paavolainen, L.; Kankkunen, E.; Nisen, H.; Jarvinen, P.; Castillon, L.; Vanharanta, S.; Vainio, P.; Kallioniemi, O.; Jaakkola, P. M.; Mirtti, T.
10.1101/2024.10.27.620479 — cancer biology — Posted on 2024-10-29
466 Identifying Modulators of Cellular Responses by Heterogeneity-sequencing
Berg, K.; Sakellaridi, L.; Rummel, T.; Hennig, T.; Whisnant, A.; Lodha, M.; Krammer, T.; Prusty, B. K.; Doelken, L.; Saliba, A.-E.; Erhard, F.
10.1101/2024.10.28.620481 — bioinformatics — Posted on 2024-10-29
469 Chromosomal and gonadal sex have differing effects on social motivation in mice
Chaturvedi, S. M.; Sarafinovska, S.; Selmanovic, D.; McCullough, K. B.; Swift, R. G.; Maloney, S. E.; Dougherty, J. D.
10.1101/2024.10.28.620727 — animal behavior and cognition — Posted on 2024-10-29
470 In-depth investigation of genome to refine QTL positions for spontaneous sex-reversal in XX rainbow trout
Dehaullon, A.; Fraslin, C.; Bestin, A.; Poncet, C.; Guiguen, Y.; Quillet, E.; Phocas, F.
10.1101/2024.10.26.620424 — genetics — Posted on 2024-10-29
473 Antarctic biosecurity policy effectively manages the rates of alien introductions
Leihy, R. I.; McGeoch, M. A.; Clarke, D. A.; Peake, L.; Buba, Y.; Belmaker, J.; Chown, S. L.
10.1101/2024.10.26.620391 — ecology — Posted on 2024-10-29
475 eIF4ET regulates meiotic proteome levels to enable oocyte formation and storage
Bhatia, P.; Amin, R.; Familiari, N. E.; Yaguchi, K.; Tran, V. M.; Bond, A.; Bukulmez, O.; Woodruff, J. B.
10.1101/2024.10.29.620718 — developmental biology — Posted on 2024-10-29
476 A mitochondrial redox switch licenses the onset of morphogenesis in animals
Kahlin, U.; Dalla Ricca, F.; Pillai, S. J.; Olivetta, M.; Tharp, K. M.; Jao, L.-E.; Dudin, O.; McDonald, K. L.; Aydogan, M. G.
10.1101/2024.10.28.620733 — developmental biology — Posted on 2024-10-29
477 Molecular dynamics of the matrisome across sea anemone life history
Bergheim, B. G.; Cole, A. G.; Rettel, M.; Stein, F.; Redl, S.; Hess, M. W.; Ikmi, A.; Özbek, S.
10.1101/2024.10.29.620203 — developmental biology — Posted on 2024-10-29
480 Sirtuin2 blockade inhibits replication of Human Immunodeficiency Virus-1 and 1 Mycobacterium tuberculosis in macrophages and humanized mice
Singh, V. K.; Mishra, A.; Troung, K.; Bohorquez, A.; Sharma, S.; Khan, A.; Bracher, F.; Zhang, K.; Endsley, J.; Endsley, M.; Rice, A. P.; Kimata, J.; Yi, G.; JAGANNATH, C.
10.1101/2024.10.27.620499 — immunology — Posted on 2024-10-29
487 Neural dynamics in the orbitofrontal cortex reveal cognitive strategies
Schiereck, S. S.; Perez-Rivera, D. T.; Mah, A.; DeMaegd, M. L.; McMahon Ward, R.; Hocker, D.; Savin, C.; Constantinople, C. M.
10.1101/2024.10.29.620879 — neuroscience — Posted on 2024-10-29
492 DNA methylation stochasticity is linked to transcriptional variability and identifies convergent epigenetic disruption across genetically-defined subtypes of AML
Hilgart, E.; Zhou, W.; Martinez-Montes, E.; Idrizi, A.; Tryggvadottir, R.; Gondek, L. P.; Majeti, R.; Ji, H.; Koldobskiy, M.; Feinberg, A. P.
10.1101/2024.10.26.620422 — cancer biology — Posted on 2024-10-29
493 Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts
McGinnis, J. H.; Enriquez, A. B.; Vandiver, F.; Bai, X.; Kim, J.; Kilgore, J.; Saha, P.; O'Hara, R.; Xie, Y.; Banaszynski, L.; Williams, N. S.; McFadden, D. G.
10.1101/2024.10.27.620498 — cancer biology — Posted on 2024-10-29
494 Disentangling the contributions of stress fibres and the unbundled actin meshwork to the anisotropy of cortical tension in response to cell shape
Fage, F.; Asnacios, S.; Pluta, A.; Richert, A.; Vias, C.; Fouchard, J.; Enslen, H.; Etienne, J.; Callan-jones, A.; THERY, M.; Pereira, D.; Asnacios, A.
10.1101/2024.10.25.620349 — biophysics — Posted on 2024-10-29
497 Unified knowledge-driven network inference from omics data
Rodriguez-Mier, P.; Garrido-Rodriguez, M.; Gabor, A.; Saez-Rodriguez, J.
10.1101/2024.10.26.620390 — bioinformatics — Posted on 2024-10-29
498 Harnessing Smartphone RGB Imagery and LiDAR Point Cloud for Enhanced Leaf Nitrogen and Shoot Biomass Assessment - Chinese Spinach as a Case Study
Harikumar, A.; Shenhar, I.; R.Pebes-Trujillo, M.; Lin, Q.; Moshelion, M.; Jie, H.; Ng, K. W.; Gavish, M.; Herrmann, I.
10.1101/2024.10.26.620395 — bioinformatics — Posted on 2024-10-29
500 Disentangling the CHAOS of intrinsic disorder in human proteins
de Vries, I.; Bak, J.; Alvarez Salmoral, D.; Xie, R.; Borza, R.; Konijnenberg, M.; Perrakis, A.
10.1101/2024.10.26.620428 — bioinformatics — Posted on 2024-10-29
502 Integer programming framework for pangenome-based genome inference
Chandra, G.; Hossen, M. H.; Scholz, S.; Dilthey, A. T.; Gibney, D.; Jain, C.
10.1101/2024.10.27.620212 — bioinformatics — Posted on 2024-10-29
503 Breaking Free: Development of Circular AAV Cargos for Targeted Seamless Integration in the Liver
Estes, B. J. G.; Gandhi, N.; Von Stetina, J.; Paudel, D.; Nan, A. X.; Amin, P.; Rose, J.; Wu, S.; Zheng, K.; Zhang, Y.; Cochrane, J. C.; Finn, J. D.; Xie, J.
10.1101/2024.10.26.620313 — bioengineering — Posted on 2024-10-29
506 Ultra-fast physics-based modeling of the elephant trunk
Kaczmarski, B. K.; Moulton, D. E.; Goriely, Z.; Goriely, A.; Kuhl, E.
10.1101/2024.10.27.620533 — bioengineering — Posted on 2024-10-29
507 Motor Equivalence in Motor Awareness
Fasola, J.; Betka, S. J. A.; Faivre, N.; Blanke, O.; Kannape, O. A.
10.1101/2024.10.29.620842 — animal behavior and cognition — Posted on 2024-10-29
508 LEGEND: Identifying Co-expressed Genes in Multimodal Transcriptomic Sequencing Data
Deng, T.; Huang, M.; Xu, K.; Lu, Y.; Xu, Y.; Chen, S.; Tao, Q.; Xie, N.; Wu, H.; Sun, X.
10.1101/2024.10.27.620451 — genomics — Posted on 2024-10-29
509 VizCNV: An integrated platform for concurrent phased BAF and CNV analysis with trio genome sequencing data
Du, H.; Lun, M. Y.; Gagarina, L.; Mehaffey, M. G.; Hwang, J. P.; Jhangiani, S. N.; Bhamidipati, S. V.; Muzny, D. M.; Poli, M. C.; Ochoa Gonzalez, S.; Chinn, I. K.; Linstrand, A.; Posey, J. E.; Gibbs, R. A.; Lupski, J. R.; Carvalho, C. M. B.
10.1101/2024.10.27.620363 — genomics — Posted on 2024-10-29
510 Probabilistic Fine-mapping of Putative Causal Genes
Okamoto, J.; Yin, X.; Ryan, B.; Chiou, J.; Luca, F.; Pique-Regi, R.; Im, H. K.; Morrison, J.; Burant, C.; Fauman, E.; Laakso, M.; Boehnke, M.; Wen, X.
10.1101/2024.10.27.620482 — genetics — Posted on 2024-10-29
511 Identification of diagnostic KASP markers for selection of crown rust resistance in oats
Nguyen, D. T.; Lewis, D.; Henningsen, E. T.; Mago, R.; Sperschneider, J.; Dodds, P.; Figueroa, M.
10.1101/2024.10.27.620528 — genetics — Posted on 2024-10-29
512 Characterization of a novel neurodevelopmental rare disease caused by a mutation within the autophagy gene ATG9B
Kilic, S.; Esmen, K.; Oto, A. M.; Kose, T. B.; Sever-Bahcekapili, M.; Eren-Kocak, E.; Demir, S.; Hiz, A. S.; Karakulah, G.; Bagriyanik, H. A.; Ozturk, M.; Diril, M. K.
10.1101/2024.10.28.620020 — genetics — Posted on 2024-10-29
513 C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A
Mirceta, M.; Schmidt, M. H. M.; Shum, N.; Prasolava, T. K.; Meikle, B.; Lanni, S.; Mohiuddin, M.; Mckeever, P. M.; Zhang, M.; Liang, M.; van der Werf, I.; Scheers, S.; Dion, P. A.; Wang, P.; Wilson, M. D.; Abell, T.; Philips, E. A.; Sznajder, L. J.; Swanson, M. S.; Mehkary, M.; Khan, M.; Yokoi, K.; Jung, C.; de Jong, P. J.; Freudenreich, C. H.; McGoldrick, P.; Yuen, R. K. C.; Abrahao, A.; Keith, J.; Zinman, L.; Robertson, J.; Rogaeva, E.; Rouleau, G. A.; Kooy, R. F.; Pearson, C. E.
10.1101/2024.10.26.620312 — genetics — Posted on 2024-10-29
515 Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions
Ardisasmita, A. I.; Joore, I. P.; Levy, N.; Myszczyszyn, A.; Marsee, A.; Sinnige, T.; Ruiter, J.; Ferdinandusse, S.; Dudaryeva, O.; Gruber, E.; Daive, V.; Levato, R.; Spee, B.; Verstegen, M.; van der Laan, L. J. W.; Nieuwenhuis, E. E. S.; Schene, I. F.; Fuchs, S.
10.1101/2024.10.29.620824 — cell biology — Posted on 2024-10-29
517 Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors
Cabezas Caballero, J.; Huhn, A.; Kutuzov, M. A.; Andre, V.; Shomuradova, A.; van der Merwe, P. A.; Dushek, O.
10.1101/2024.10.25.620274 — immunology — Posted on 2024-10-29
519 Predicting Immunogenic CD4+ T Cell Epitopes in Bacteria Using Antigen and Peptide Features
Marrama, D.; Battey, H.; Khaledian, E.; Muller, M.; Panda, S.; da Silva Antunes, R.; Sette, A.; Lindestam Arlehamn, C. S.; Peters, B.
10.1101/2024.10.25.620357 — immunology — Posted on 2024-10-29
521 Sensitivity to photoperiod is a complex trait in Camelina sativa
Ramirez-Corona, B.; Seagren, E.; Sherman, C.; Imaizumi, T.; Queitsch, C.; Cuperus, J.
10.1101/2024.10.25.620367 — plant biology — Posted on 2024-10-29
523 The Arabidopsis amino acid transporter UmamiT20 confers susceptibility to B. cinerea
Prior, M.; Weidauer, D.; Liao, J.-Y.; Kuwata, K.; Locci, F.; Deng, C.; Ye, H. B.; Cai, Q.; Bezrutczyk, M.; Zhao, C.; Chen, L.-Q.; Jonikas, M.; Pilot, G.; Jin, H.; Parker, J.; Frommer, W. B.; Kim, J.-Y.
10.1101/2024.10.26.620370 — plant biology — Posted on 2024-10-29
524 Mechanical regulation of tissue flatness in Marchantia
Ferria, J.; Fournie, C. J. A.; Jankowska, M. H.; Grossman, D.; Roeder, A. H. K.; Drevensek, S.; Boudaoud, A.
10.1101/2024.10.25.620180 — plant biology — Posted on 2024-10-29
525 Analysis of the progression of cervical cancer in Guatemala- from pre-malignancy to invasive disease
Robinson, E.; Rodriguez, I.; Argueta, V.; Xie, Y.; Lou, H.; Milano, R.; Lee, H. J.; Burdett, L.; Mishra, S. K.; Yeager, M.; Mirabello, L.; Dean, M.; Orozco, R.
10.1101/2024.10.25.620123 — cancer biology — Posted on 2024-10-29
528 DNA nanodevice for analysis of force-activated protein extension and interactions
Zhou, K.; Chung, M.; Cheng, J.; Powell, J. T.; Liu, J.; Xiong, Y.; Schwartz, M. A.; Lin, C.
10.1101/2024.10.25.620262 — biophysics — Posted on 2024-10-29
529 Cell2Sentence: Teaching Large Language Models the Language of Biology
Levine, D.; Rizvi, S. A.; Levy, S.; Pallikkavaliyaveetil, N.; Zhang, D.; Chen, X.; Ghadermarzi, S.; Wu, R.; Zhang, Z.; Vrkic, I.; Zhong, A.; Raskin, D.; Han, I.; Fonseca, A.; Ortega Caro, J.; Karbasi, A.; Dhodapkar, R. M.; van Dijk, D.
10.1101/2023.09.11.557287 — bioinformatics — Posted on 2024-10-29
530 Integration of protein and coding sequences enables mutual augmentation of the language model
Zhao, H.-R.; Cheng, M.-T.; Zhu, J.; Wang, H.; Yang, X.-R.; Wang, B.; Sun, Y.-X.; Fang, M.-H.; Chen, E.; Li, H.; Han, S.-J.; Chen, Y.; Zhou, C.-Z.
10.1101/2024.10.24.620004 — bioinformatics — Posted on 2024-10-29
531 Towards Robust Evaluation of Protein Generative Models: A Systematic Analysis of Metrics
Strashnov, P.; Shevtsov, A.; Meshchaninov, V.; Ivanova, M.; Nikolaev, F.; Kardymon, O.; Vetrov, D.
10.1101/2024.10.25.620213 — bioinformatics — Posted on 2024-10-29
532 Decoding the Functional Interactome of Non-Model Organisms with PHILHARMONIC
Sledzieski, S.; Versavel, C.; Singh, R.; Ocitti, F.; Devkota, K.; Kumar, L.; Shpilker, P.; Roger, L.; Yang, J.; Lewinski, N.; Putnam, H. M.; Berger, B.; Klein-Seetharaman, J.; Cowen, L.
10.1101/2024.10.25.620267 — bioinformatics — Posted on 2024-10-29
533 Binning meets taxonomy: TaxVAMB improves metagenome binning using bi-modal variational autoencoder
Kutuzova, S.; Piera Lindez, P.; Nor Nielsen, K.; S. Olsen, N.; Riber, L.; Gobbi, A.; Forero Junco, L. M.; Erdmann Dougherty, P.; Cairo Westergaard, J.; Christensen, S.; Hestbjerg Hansen, L.; Nielsen, M.; Nybo Nissen, J.; Rasmussen, S.
10.1101/2024.10.25.620172 — bioinformatics — Posted on 2024-10-29
535 PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data
de Visser, M. C.; Ploeg, C. v. d.; Cvijanovic, M.; Vucic, T.; Theodoropoulos, A.; Wielstra, B.
10.1101/2024.10.25.620064 — bioengineering — Posted on 2024-10-29
536 Scalable Fabrication of a Tough and Recyclable Spore-Bearing Biocomposite Thermoplastic Polyurethane
Kim, H. S.; White, E.; Crane, G.; Patel, K.; Noh, M. H.; Rahman, M. A.; Feist, A.; Locklin, J.; Pokorski, J.
10.1101/2024.10.25.620092 — bioengineering — Posted on 2024-10-29
537 Optical Clearing with Tartrazine Enables Deep Transscleral Imaging with Optical Coherence Tomography
Narawane, A.; Trout, R.; Viehland, C.; Kuo, A. N.; Vajzovic, L.; Dhalla, A.-H.; Toth, C. A.
10.1101/2024.10.25.620343 — bioengineering — Posted on 2024-10-29
541 Immune escape and replicative capacity of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1
Bekliz, M.; Essaidi-Laziosi, M.; Adea, K.; Hosszu-Fellous, K.; Alvarez, C.; Bellon, M.; Sattonnet-Roche, P.; Puhach, O.; Dbeissi, D.; Zaballa, M. E.; Stringhini, S.; Guessous, I.; Vetter, P.; Eberhardt, C. S.; Kaiser, L.; Eckerle, I.
10.1101/2024.02.14.579654 — microbiology — Posted on 2024-10-29
545 Altered systemic bioenergetic reserve in chronic kidney disease predisposes hearts to worse functional outcomes
Young, M.; Aastrup, M.; Patel, N.; Cullen, F.; Hansen, E. S. S.; Clark, J. E.; Eykyn, T. R.; Vaeggemose, M.; Vujic, A.; Karatzia, L.; Valkovic, L.; Miller, J. J. J. J.; Buus, N. H.; Laustsen, C.; Yaqoob, M. M.; Aksentijevic, D.
10.1101/2024.10.24.620055 — physiology — Posted on 2024-10-29
551 Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading.
Kennedy, D. R.; Lemiere, J.; Tan, C.; Simental, E.; Braxton, J.; Maxwell, R. A.; Amine, A. A.; Al-Sady, B.
10.1101/2024.10.25.620326 — molecular biology — Posted on 2024-10-29
553 Tumor-specific antibodies elicited by engineered bacteria promote bladder cancer immunotherapy
Rouanne, M.; Chen, N.; Mariuzza, D. L.; Li, F.; de los Santos-Alexis, K.; Savage, T. M.; Vincent, R. L.; Mendelsohn, C. L.; Danino, T.; Arpaia, N.
10.1101/2024.10.24.620122 — immunology — Posted on 2024-10-29
554 RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress
Jernigan, J. E.; Staley, H. A.; Baty, Z.; Bolen, M. L.; Gomes, B. N.; Holt, J.; Cole, C. L.; Neighbarger, N. K.; Dheeravath, K.; Merchak, A. R.; Menees, K. B.; Coombes, S. A.; Tansey, M. G.
10.1101/2024.10.24.620078 — immunology — Posted on 2024-10-29
555 CpGPT: a Foundation Model for DNA Methylation
de Lima Camillo, L. P.; Sehgal, R.; Armstrong, J.; Higgins-Chen, A. T.; Horvath, S.; Wang, B.
10.1101/2024.10.24.619766 — systems biology — Posted on 2024-10-29
558 A tumor-secreted protein utilizes glucagon release to cause host wasting
Ding, G.; Li, Y.; Cheng, C.; Tan, K.; Deng, Y.; Pang, H.; Wang, Z.; Dang, P.; Wu, X.; Rushworth, E.; Yuan, Y.; Yang, Z.; Song, W.
10.1101/2024.10.24.619567 — physiology — Posted on 2024-10-29
559 Dietary control of peripheral adipose storage capacity through membrane lipid remodelling
Tol, M. J.; Shimanaka, Y.; Bedard, A. H.; Sapia, J.; Cui, L.; Colaco-Gaspar, M.; Hofer, P.; Ferrari, A.; Qian, K.; Kennelly, J. P.; Lee, S. D.; Gao, Y.; Xiao, X.; Gao, J.; Mack, J. J.; Weston, T. A.; Pan, C.; Lusis, A. J.; Williams, K. J.; Su, B.; Pike, D. P.; Reed, A.; Milosevich, N.; Cravatt, B. F.; Arita, M.; Young, S. G.; Ford, D. A.; Zechner, R.; Vanni, S.; Tontonoz, P.
10.1101/2024.10.25.620374 — physiology — Posted on 2024-10-29
561 Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting
Ponte, M. E.; Prom, J. C.; Newcomb, M. A.; Jordan, A. B.; Comfort, L. L.; Hu, J.; Geisler, C. E.; Hayes, M. R.; Morris, E. M.
10.1101/2024.10.24.620086 — physiology — Posted on 2024-10-29
562 Pseudomonas aeruginosa metabolite 3-oxo-C12HSL induces apoptosis through T2R14 and the mitochondrial calcium uniporter
Miller, Z. A.; Mueller, A.; Thompson, J. C.; Sywanycz, S. M.; Hill, B. L.; Carey, R. M.; Lee, R. J.
10.1101/2024.10.24.620094 — physiology — Posted on 2024-10-29
563 CIGB-300 reverses chemo-resistance in MDR1-transfected lung squamous cancer cells
Wang, M.; Tang, D.; Luo, X.; Liu, W.; Xie, J.; Yi, Y.; Lan, Y.; Li, W.; Perea, S. E.; Dessie, W.; Perera, Y.; Qin, Z.
10.1101/2024.10.24.620006 — cancer biology — Posted on 2024-10-29
564 IL-13/IL-13Rα2 axis promotes proliferation of angiosarcoma cells
Saito, H.; Omori, I.; Iwasawa, O.; Sugimori, A.; Nakajima, H.; Ichimura, R.; Sato, S.; Sumida, H.
10.1101/2024.10.24.619789 — cancer biology — Posted on 2024-10-29
565 Structural and functional insights into nuclear role of Parkinson's Disease-associated α-Synuclein
Jos, S.; Kambaru, A.; Prasad, T. K.; Parthasarathi, S.; Kamariah, N.; Nath, S.; Balasundaram, P.; Padavattan, S.
10.1101/2024.10.24.620072 — biophysics — Posted on 2024-10-29
567 V- and VL-Scores Uncover Viral Signatures and Origins of Protein Families
Zhou, K.; Kosmopoulos, J. C.; Dieppa Colon, E.; Badciong, P. J.; Anantharaman, K.
10.1101/2024.10.24.619987 — bioinformatics — Posted on 2024-10-29
569 The metabolic costs of meiotic drive
Bradshaw, S. L.; Rodriguez, E.; Wang, H.; Yu, C. T.; De La Noue, C. D. V.; Hafezjee, A.; Pomiankowski, A.; Camus, M. F.
10.1101/2024.10.24.620073 — evolutionary biology — Posted on 2024-10-29
570 Genomic, phenotypic and environmental correlates of speciation in the midwife toads (Alytes)
Ambu, J.; Litvinchuk, S. N.; Caballero-Diaz, C.; Nicieza, A.; Velo-Anton, G.; Goncalves, H.; Martinez-Freiria, F.; Martinez-Gil, H.; Beltran, J. F.; Donaire-Barroso, D.; Hernandez, A.; Suchan, T.; Crochet, P.-A.; Martinez-Solano, I.; Dufresnes, C.
10.1101/2024.10.24.619835 — evolutionary biology — Posted on 2024-10-29
573 Serum and Tear Autoantibodies from NOD and NOR Mice as Potential Diagnostic Indicators of Local and Systemic Inflammation in Sjögren's Disease
Kakan, S. S.; Abdelhamid, S.; Ju, Y.; Mackay, J. A.; Edman-Woolcott, M. C.; Raman, I.; Zhu, C.; Raj, P.; Hamm-Alvarez, S. F.
10.1101/2024.10.24.619993 — immunology — Posted on 2024-10-29
574 Capturing single-molecule properties does not ensure accurate prediction of biomolecular phase diagrams
Feito, A.; Sanchez-Burgos, I.; Rey, A.; Collepardo-Guevara, R.; Espinosa, J. R.; Tejedor, A. R.
10.1101/2024.10.24.619983 — biophysics — Posted on 2024-10-29
576 Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications
Perez-Rafols, A.; Perez-Ropero, G.; Cerofolini, L.; Sperotto, L.; Roca-Martinez, J.; Anahi Higuera-Rodriguez, R.; Russomanno, P.; Kaiser, W.; Vranken, W. F.; Danielson, H.; Provenzani, A. F.; Martelli, T.; Sattler, M.; Buijs, J.; Fragai, M.
10.1101/2024.10.24.619864 — biophysics — Posted on 2024-10-29
583 Pervasive fitness trade-offs revealed by rapid adaption in large experimental populations of Drosophila melanogaster
Bitter, M. C.; Greenblum, S.; Rajpurohit, S.; Bergland, A. O.; Hemker, J. A.; Betancourt, N. J.; Tilk, S.; Berardi, S.; Oken, H.; Schmidt, P.; Petrov, D.
10.1101/2024.10.28.620721 — evolutionary biology — Posted on 2024-10-29
584 TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites
Murphy, R. D.; Troublefield, C. A.; Miracle, J. S.; Young, L. E. A.; Tripathi, A.; Brizzee, C. O.; Dhara, A.; Patwardhan, A.; Sun, R. C.; Vander Kooi, C. W.; Gentry, M. S.; Sinai, A. P.
10.1101/2023.09.29.560185 — microbiology — Posted on 2024-10-29
587 Ligand-Mediated Endocytosis Is Regulated in a Sexually Dimorphic Way in Osteocytes in vivo
Matthews, M. D.; Saffari, A. W.; Mukul, N. A.; Hai, J.; Wiesner, U. B.; Lewis, K. J.
10.1101/2024.08.18.608500 — bioengineering — Posted on 2024-10-29
588 Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP
Leveille, A. N.; Schwarzrock, T.; Brown, H.; True, B.; Plasencia, J.; Neudecker, P.; Üffing, A.; Weiergraber, O. H.; Willbold, D.; Kritzer, J.
10.1101/2024.02.25.581879 — biochemistry — Posted on 2024-10-29
589 My friend MIROSLAV: A Hackable Open-Source Hardware and Software Platform for High-Throughput Rodent Activity Monitoring in the Home Cage
Virag, D.; Homolak, J.; Kodvanj, I.; Vargantolic, A.-M.; Babic Perhoc, A.; Meglic, P.; Sostaric Muzic, P.; Knezovic, A.; Osmanovic Barilar, J.; Cifrek, M.; Trkulja, V.; Salkovic-Petrisic, M.
10.1101/2024.06.25.600592 — animal behavior and cognition — Posted on 2024-10-29
590 Aging at scale: Younger dogs and larger breeds from the Dog Aging Project show accelerated epigenetic aging.
McCoy, B. M.; Mariner, B. L.; Cheng, C. F.; Slikas, E.; Adjangba, C.; Greenier, A.; Brassington, L.; Marye, A.; Harrison, B. R.; Partida-Aguilar, M.; Bamberger, T.; Algavi, Y.; Muller, E.; Harris, A.; Rout, E.; The Dog Aging Project Consortium, ; Avery, A.; Borenstein, E.; Promislow, D.; Snyder-Mackler, N.
10.1101/2024.10.03.616519 — genomics — Posted on 2024-10-29
591 Methylomes reveal recent evolutionary changes in populations of two plant species
Korfmann, K.; Zauchner, A.; Huo, B.; Grünke, C.; Wang, Y.; Tellier, A.; Arunkumar, R.
10.1101/2024.09.30.615871 — evolutionary biology — Posted on 2024-10-29
595 Amoeboid cells undergo durotaxis with soft end polarized NMIIA
Kang, C.; Chen, P.; Yi, X.; Li, D.; Hu, Y.; Yang, Y.; Cai, H.; Li, B.; Wu, C.
10.1101/2023.04.13.536664 — cell biology — Posted on 2024-10-29
596 Epithelial microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants
Weight, C. M.; Pollara, G. M.; Betts, M.; Ragazzini, R.; Connor, M.; Ramos-Sevillano, E.; Reine, J.; Whelan, M.; Guerra-Assuncao, J. A.; Bonfanti, P.; Jolly, C.; Noursadeghi, M.; Ferreira, D.; Brown, J.; Heyderman, R. S.
10.1101/2023.06.15.545009 — microbiology — Posted on 2024-10-29
597 Activity-dependent extracellular proteolytic cascade remodels ECM to promote structural plasticity
Singh, J. B.; Perello Amoros, B.; Schneeberg, J.; Seidenbecher, C. I.; Fejtova, A.; Dityatev, A.; Frischknecht, R.
10.1101/2024.10.28.620597 — neuroscience — Posted on 2024-10-29
598 behaviorMate: An Intranet of Things Approach for Adaptable Control of Behavioral and Navigation-Based Experiments
Bowler, J. C.; Zakka, G.; Yong, H. C.; Li, W.; Rao, B.; Liao, Z.; Priestley, J. B.; Losonczy, A.
10.1101/2023.12.04.569989 — neuroscience — Posted on 2024-10-29
599 Separating the control of moving and holding in post-stroke arm paresis
Hadjiosif, A. M.; Kita, K.; Albert, S. T.; Scheidt, R. A.; Shadmehr, R.; Krakauer, J. W.
10.1101/2022.11.26.517884 — neuroscience — Posted on 2024-10-29
600 Neural Mechanisms of Feedback Processing and Regulation Recalibration during Neurofeedback Training
Pamplona, G. S. P.; Zweerings, J.; Lor, C. S.; deErney, L.; Roecher, E.; Taebi, A.; Hellrung, L.; Amano, K.; Scheinost, D.; Krause, F.; Rosenberg, M. D.; Ionta, S.; Brem, S.; Hermans, E.; Mathiak, K.; Scharnowski, F.
10.1101/2024.08.19.608543 — neuroscience — Posted on 2024-10-29
604 Unbiased identification of cell identity in dense mixed neural cultures
De Beuckeleer, S.; Van De Looverbosch, T.; Van Den Daele, J.; Ponsaerts, P.; De Vos, W.
10.1101/2024.01.06.574474 — cell biology — Posted on 2024-10-29
607 Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils
Etani, H.; Takatori, S.; Wang, W.; Omi, J.; Akahori, A.; Watanabe, H.; Sonn, I.; Okano, H.; Hara, N.; Hasegawa, M.; Miyashita, A.; Kikuchi, M.; Ikeuchi, T.; Morishima, M.; Saito, Y.; Murayama, S.; Saito, T.; Saido, T. C.; Takai, T.; Ohwada, T.; Aoki, J.; Tomita, T.
10.1101/2024.05.08.593262 — neuroscience — Posted on 2024-10-29
609 From spreadsheet lab data templates to knowledge graphs: A FAIR data journey in the domain of AMR research
Gadiya, Y.; Abbassi-Daloii, T.; Ioannidis, V.; Juty, N.; Stie Kallesoe, C.; Attwood, M.; Kohler, M.; Gribbon, P.; Witt, G.
10.1101/2024.07.18.604030 — bioinformatics — Posted on 2024-10-29
610 Pervasive and recurrent hybridisation prevents inbreeding depression in Europe's most threatened seabird
Izquierdo-Aranega, G.; Cuevas-Caballe, C.; Giannelli, F.; Paris, J. R.; Bourgeois, K.; Trucchi, E.; Gonzalez-Solis, J.; Riutort, M.; Ferrer Obiol, J.; Rozas, J.
10.1101/2024.10.24.619781 — evolutionary biology — Posted on 2024-10-29
611 Mu opioid receptor expression by nucleus accumbens inhibitory interneurons promotes affiliative social behavior
Toddes, C.; Lefevre, E. M.; Retzlaff, C. L.; Zugschwert, L.; Khan, S.; Myhre, E.; Gauthier, E. A.; Fernandez de Velasco, E. M.; Kieffer, B. L.; Rothwell, P. E.
10.1101/2024.10.28.620729 — neuroscience — Posted on 2024-10-29
613 Epigenetic constraint of cellular genomes evolutionarily links genetic variation to function
Sinniah, E.; Mizikovsky, D.; Shim, W. J.; Chow, C. S. Y.; Souilmi, Y.; Cheng, F.-F.; Zheng, Z.; Laurie, J.; Foster, M.; Shah, S.; Boden, M.; Zeng, J.; Llamas, B.; Palpant, N.
10.1101/2024.10.28.620690 — genetics — Posted on 2024-10-29
614 Geographically widespread and novel hemotropic mycoplasmas and bartonellae in Mexican free-tailed bats and sympatric North American bat species
Becker, D.; Dyer, K.; Lock, L.; Olbrys, B.; Pladas, S.; Sukhadia, A.; Demory, B.; Nunes Batista, J.; Pineda, M.; Simmons, N.; Adams, A.; Frick, W.; O'Mara, T.; Volokhov, D.
10.1101/2024.02.08.577874 — ecology — Posted on 2024-10-28
617 Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing
Robinson, J. W.; Bechard, A. T.; Evans, M. R.; Mosuro, K.; Isaacson, J. R.; Pillay, S.; Lin, D. S.; Sahota, A.; de Belle, J. N.; Robinson, G. I.; Strong, M. J.; Simon, A. F.
10.1101/2024.10.28.620699 — animal behavior and cognition — Posted on 2024-10-28
618 Oxytocin receptor controls distinct components of pair bonding and development in prairie voles
Sharma, R.; Berendzen, K. M.; Everitt, A.; Wang, B.; Williams, G.; Wang, S.; Quine, K.; Larios, R. D.; Long, K. L. P.; Hoglen, N.; Sulaman, B. A.; Heath, M. C.; Sherman, M.; Kinkel, M.; Cai, A.; Galo, D.; Caamal, L. C.; Goodwin, N. L.; Beery, A.; Bales, K. L.; Pollard, K. S.; Willsey, A. J.; Manoli, D. S.
10.1101/2024.09.25.613753 — neuroscience — Posted on 2024-10-28
619 Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk
Ajunwa, C. C.; Zhang, J.; Collin, G.; Xu, L.; Keshavan, M. S.; Tang, Y.; Zhang, T.; Li, H.; Shenton, M. E.; Stone, W. S.; Wang, J.; Niznikiewicz, M.; Whitfield-Gabrieli, S.
10.1101/2024.10.25.620271 — neuroscience — Posted on 2024-10-28
620 Smad4 and TGF-β1 dependent gene expression biomarkers in conditional intestinal adenoma, organoids and colorectal cancer.
Surakhy, M.; Matheson, J.; Barnes, D.; Carter, E.; Hughes, J.; Bühnemann, C.; Sanegre, S.; Morreau, H.; Metz, P.; Imianowski, C. J.; HASSAN, A. B.
10.1101/2024.03.15.584288 — cancer biology — Posted on 2024-10-28
621 Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma
Popova, L. V.; Garfinkle, E. A. R.; Chopyk, D. M.; Navarro, J. B.; Rivaldi, A.; Shu, Y.; Lomonosova, E.; Phay, J. E.; Miller, B. S.; Sattuwar, S.; Mardis, E. R.; Miller, K. E.; Dedhia, P. H.
10.1101/2024.09.30.615695 — cancer biology — Posted on 2024-10-28
622 Biom3d, a modular framework to host and develop 3D segmentation methods
Mougeot, G.; Safarbati, S.; Alegot, H.; Pouchin, P.; Field, N.; Almagro, S.; Pery, E.; Probst, A.; Tatout, C.; Evans, D. E.; Graumann, K.; Chausse, F.; Desset, S.
10.1101/2024.07.25.604800 — bioinformatics — Posted on 2024-10-28
623 An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans
Wu, J.; Xi, J.; Zhu, Z.; Peng, Q.; Liu, C.; Cao, Y.; Wan, Z.; Chen, X.; Luan, Y.
10.1101/2024.08.27.610021 — bioengineering — Posted on 2024-10-28
625 Proximity Interactome analyses unveil novel regulators of IRE1a canonical signaling
Le Goupil, S.; Philippe, C.; Laprade, H.; Lode, M.; Boniface, R.; Pelizzari-Raymundo, D.; Dejgaard, K.; Jansen, G.; Limia, C.; Hetz, C.; Mahdizadeh, S. J.; Negroni, L.; AUBRY, M.; Ricci, J.-E.; Eriksson, L. A.; chevet, e.
10.1101/2024.10.27.620453 — biochemistry — Posted on 2024-10-28
626 Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2
Szeto, J.-Y. A.; Vivoli Vega, M.; Mailliot, J.; Orriss, G.; Sun, L.; Bufton, J. C.; Powers, K. T.; Yadav, S. K. N.; Berger, I.; Schaffitzel, C.
10.1101/2024.10.26.620407 — biochemistry — Posted on 2024-10-28
627 Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels
Hooda, Y.; Sente, A.; Judy, R. M.; Smalinskaite, L.; Peak-Chew, S.-Y.; Naydenova, K.; Malinauskas, T.; Hardwick, S. W.; Chirgadze, D. Y.; Aricescu, A. R.; Hegde, R. S.
10.1101/2024.10.28.620708 — biochemistry — Posted on 2024-10-28
628 Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy
Lichauco, C.; Foss, E. J.; Gatbonton-Schwager, T.; Athow, N. F.; Lofts, B.; Acob, R.; Taylor, E.; Marquez, J. J.; Lao, U.; Miles, s.; Bedalov, A.
10.1101/2024.03.21.586113 — genetics — Posted on 2024-10-28
630 The genomic signature and transcriptional response of metal tolerance in brown trout inhabiting metal-polluted rivers
Paris, J. R.; King, R. A.; Ferrer Obiol, J.; Shaw, S.; Lange, A.; Bourret, V.; Hamilton, P. B.; Rowe, D.; Laing, L. V.; Farbos, A.; Moore, K. A.; Urbina, M. A.; van Aerle, R.; Catchen, J. M.; Wilson, R. W.; Bury, N. R.; Santos, E. M.; Stevens, J. R.
10.1101/2024.05.30.595956 — evolutionary biology — Posted on 2024-10-28
631 Extreme in Every Way: Exceedingly Low Genetic Diversity in Snow Leopards Due to Persistently Small Population Size
Solari, K. A.; Morgan, S. A.; Poyarkov, A. D.; Weckworth, B.; Samelius, G.; Sharma, K.; Ostrowski, S.; Ramakrishnan, U.; Kubanychbekov, Z.; Kachel, S.; Johansson, O.; Lkhagvajav, P.; Hemmingmoore, H.; Aleksandrov, D.; Bayaraa, M.; Grachev, A.; Korablev, M. P.; Hernandez-Blanco, J. A.; Munkhtsog, B.; Rosenbaum, B.; Rozhnov, V. V.; Rajabi, A. M.; Noori, H.; Suryawanshi, K.; Armstrong, E. E.; Petrov, D.
10.1101/2023.12.14.571340 — evolutionary biology — Posted on 2024-10-28
632 Methylomes reveal recent evolutionary changes in populations of two plant species
Korfmann, K.; Zauchner, A.; Huo, B.; Grünke, C.; Wang, Y.; Tellier, A.; Arunkumar, R.
10.1101/2024.09.30.615871 — evolutionary biology — Posted on 2024-10-28
633 Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis
Huang, Y.-T.; Abdrabo, K. A. E.-S.; Phang, G. J.; Fan, Y.-H.; Wu, Y.-T.; Ou, J.-H.; Hulcr, J.
10.1101/2024.10.09.617500 — evolutionary biology — Posted on 2024-10-28
635 ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing.
Pandey, A.; Cousin, H.; Kumar, S.; Taylor, L.; Chander, A.; Coppenrath, K.; Shaidani, N.-I.; Horb, M.; Alfandari, D.
10.1101/2024.08.18.608474 — developmental biology — Posted on 2024-10-28
636 Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage
Anjum, H.; Smith, J. P.; Martini, A. G.; Yacu, G. S.; Medrano, S.; Gomez, R. A.; Sequeira-Lopez, M. L. S.; Quaggin, S. E.; Finer, G.
10.1101/2024.03.25.586641 — developmental biology — Posted on 2024-10-28
637 Visualizing liquid-liquid phase transitions
Sahoo, B. R.; Deng, X.; Wong, E. L.; Clark, N.; Yang, H.; Subramanian, V.; Guzman, B. B.; Harris, S. E.; Dehury, B.; Miyashita, E.; Hoff, J. D.; Kocman, V.; Saito, H.; Dominguez, D.; Plavec, J.; Bardwell, J. C.
10.1101/2023.10.09.561572 — cell biology — Posted on 2024-10-28
638 Regulation of Diseases-Associated Microglia in the Optic Nerve by Lipoxin B4 and Ocular Hypertension
Maurya, S.; Lin, M.; Karnam, S.; Singh, T.; Kumar, M.; Ward, E. L.; Sivak, J.; Flanagan, J.; Gronert, K.
10.1101/2024.03.18.585452 — molecular biology — Posted on 2024-10-28
639 Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish
Lopez-Blanch, L.; Rodriguez-Marin, C.; Mantica, F.; Iniguez, L. P.; Permanyer, J.; Kita, E. M.; Mackensen, T.; Codina-Tobias, M.; Romero-Ferrero, F.; Fernandez-Albert, J.; Cuadrado, M.; Bustelo, X. R.; de Polavieja, G.; Irimia, M.
10.1101/2024.10.23.619860 — molecular biology — Posted on 2024-10-28
642 Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks
Tejada-Arranz, A.; Plack, A.; Antelo-Varela, M.; Kaczmarczyk, A.; Klotz, A.; Jenal, U.; Basler, M.
10.1101/2024.10.26.620397 — microbiology — Posted on 2024-10-28
644 Towards a complete phage tail fiber structure atlas.
Klein-Sousa, V.; Roa-Eguiara, A.; Kielkopf, C. S.; Sofos, N.; Taylor, N. M. I.
10.1101/2024.10.28.620165 — microbiology — Posted on 2024-10-28
646 The mechanism of spatial pattern transition in motile bacterial collectives
Saulnier, J.-B.; Romanos, M.; Schrohe, J.; Cuzin, C.; Calvez, V.; Mignot, T.
10.1101/2024.10.28.620572 — microbiology — Posted on 2024-10-28
647 Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans
Asiimwe, R.; Knott, B.; Greene, M. E.; Wright, E.; Bell, M.; Epstein, D.; Yates, S. D.; Gonzalez, M. V.; Fry, S.; Boydston, E.; Clevenger, S.; Locke, J. E.; Brocato, B. E.; Burgan, C. M.; Burney, R.; Arora, N.; Duncan, V. E.; Richter, H. E.; Gunn, D.; Freud, A. G.; Little, S. C.; Porrett, P. M.
10.1101/2024.03.07.583906 — immunology — Posted on 2024-10-28
648 CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes.
Durgam, S. S.; Rosado sanchez, I.; Yin, D.; Speck, M.; Mojibian, M.; Sayin, I.; Hynes, G.; Alegre, M.-L.; Levings, M. K.; Chong, A. S.
10.1101/2024.09.20.614149 — immunology — Posted on 2024-10-28
649 Displacement of extracellular chloride by immobile anionic constituents of the brain's extracellular matrix
Normoyle, K. P.; Lillis, K. P.; Egawa, K.; McNally, M. A.; Paulchakrabarti, M.; Coudhury, B. P.; Lau, L. A.; Shiu, T.; Staley, K. J.
10.1101/2022.12.28.522113 — neuroscience — Posted on 2024-10-28
652 Enabling Electric Field Model of Microscopically Realistic Brain
Qi, Z.; Noetscher, G. M.; Miles, A.; Weise, K.; Knosche, T.; Cadman, C. R.; Potashinsky, A. R.; Liu, K.; Wartman, W. A.; Nunez Ponasso, G. C.; Bikson, M.; Lu, H.; Deng, Z.-D.; Nummenmaa, A.; Makaroff, S. N.
10.1101/2024.04.04.588004 — neuroscience — Posted on 2024-10-28
653 Information transmission in a cell monolayer: A numerical study
Nałecz-Jawecki, P.; Szyc, P.; Grabowski, F.; Kochanczyk, M.; Lipniacki, T.
10.1101/2024.06.21.600012 — systems biology — Posted on 2024-10-28
656 Operate a Cell-Free Biofoundry using Large Language Models
Herisson, J.; Hoang, N. A.; El Sawah, A.; Mahdy Khalil, M.; Faulon, J.-L.
10.1101/2024.10.28.619828 — synthetic biology — Posted on 2024-10-28
657 Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry
Wilson, C. M.; Pommier, G. C.; Richman, D. D.; Sambold, N.; Hussmann, J. A.; Weissman, J. S.; Gilbert, L. A.
10.1101/2024.10.28.620517 — synthetic biology — Posted on 2024-10-28
660 Developmental variability in cotton fiber cell wall properties linked to important agronomic traits
Wilson, M. C.; Howell, A. H.; Sood, A.; Lee, Y.; Yang, P.; Rani, H.; Yu, E.; Mallery, E. L.; Swaminathan, S.; Grover, C. E.; Wendel, J. F.; Zabotina, O. A.; Xie, J.; Davis, C. S.; Szymanski, D.
10.1101/2024.08.19.607249 — plant biology — Posted on 2024-10-28
664 Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets
Nicholson, T. M.; Tokihiro, J. C.; Tu, W.-c.; Khor, J. W.; Lee, U. N.; Berthier, E.; Amory, J. K.; Walsh, T. J.; Muller, C. H.; Theberge, A. B.
10.1101/2024.05.09.593416 — bioengineering — Posted on 2024-10-28
666 Structure of a Putative Terminal Amidation Domain in Natural Product Biosynthesis
Rankin, M. R.; Khare, D.; Gerwick, L.; Sherman, D. H.; Gerwick, W. H.; Smith, J. L.
10.1101/2024.10.28.620694 — biochemistry — Posted on 2024-10-28
669 A complete approach for circRNA therapeutics from purification to lyophilized delivery using novel ionizable lipids
Broset, E.; Lampaya, V.; Larraga, A.; Navarro, V.; Lopez, A.; de Miguel, D.; Pena, A.; Martinez-Olivan, J.; Casabona, D.
10.1101/2024.10.28.620632 — molecular biology — Posted on 2024-10-28
670 Functional interaction between transcription factor Sfp1 and the NuA4 complex in response to nutrient availability
Xu, K.; Joly-Beauparlant, C.; Bianco, S.; Cote, V.; Herrmann, L.; Droit, A.; Downey, M.; Nourani, A.; Cote, J.
10.1101/2024.10.28.620578 — molecular biology — Posted on 2024-10-28
671 Prostate-specific membrane receptor PPAP facilitates E. coli invasion of luminal prostate cells via FimH binding
Guedes, M.; Joshi, A.; Dorn, S.; Peters, S.; Beste, T.; Leipold, A. M.; Rosenfeldt, M.; Saliba, A.-E.; Dobrindt, U.; Kalogirou, C.; Aguilar, C.
10.1101/2024.10.28.620623 — molecular biology — Posted on 2024-10-28
673 Borrelia burgdorferi loses essential genetic elements and cell proliferative potential during stationary phase in culture but not in the tick vector.
Zhang, J.; Takacs, C. N.; McCausland, J. W.; Mueller, E.; Buron, J.; Thappeta, Y.; Wachter, J.; Rosa, P. A.; Jacobs-Wagner, C.
10.1101/2024.10.28.620338 — microbiology — Posted on 2024-10-28
676 Complex system modelling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteria
Mukherjee, S. D.; Batagello, C.; Adler, A.; Agudelo, J.; Zampini, A.; Suryavanshi, M.; Nguyen, A.; Orr, T.; Dearing, D.; Monga, M.; Miller, A. W.
10.1101/2024.10.28.620613 — microbiology — Posted on 2024-10-28
677 Coordinated conformational changes in the Tad pilus ATPase CpaF facilitate a rotary mechanism of catalysis
Yen, I. Y.; Whitfield, G. B.; Rubinstein, J. L.; Burrows, L. L.; Brun, Y. V.; Howell, P. L.
10.1101/2024.10.28.620641 — microbiology — Posted on 2024-10-28
680 Genome Analyses of A Worldwide Multisource Collection of Klebsiella variicola Reveal Adaptation Relevant for Human Infection
Wang, J.; Coipan, C.; Franz, E.; Kuijper, E.; Wessels, E.; Gally, D.; Vasudevan, K.; Veeraraghavan, B.; Farzana, R.; Holden, N.; Zadoks, R. N.; Higgins, P.; Schneiders, T.
10.1101/2024.10.28.617863 — microbiology — Posted on 2024-10-28
682 Brown adipose tissue thermogenesis rhythms are driven by the SCN independent of adipocyte clocks
Paschos, G. K.; Lordan, R.; Hollingsworth, T.; Lekkas, D.; Kelch, S.; Loro, E.; Verginadis, I.; Khurana, T.; Sengupta, A.; Weljie, A.; FitzGerald, G. A.
10.1101/2024.10.28.620609 — physiology — Posted on 2024-10-28
684 PhenoScreen: A Dual-Space Contrastive Learning Framework-based Phenotypic Screening Method by Linking Chemical Perturbations to Cellular Morphology
Wang, S.; Han, Q.; Qin, W.; Wang, L.; Yuan, J.; Zhao, Y.; Ren, P.; Zhang, Y.; Tang, Y.; Li, R.; Li, Z.; Zhang, W.; Gao, S.; Bai, F.
10.1101/2024.10.23.619752 — bioinformatics — Posted on 2024-10-28
685 Oatk: a de novo assembly tool for complex plant organelle genomes
Zhou, C.; Brown, M.; Blaxter, M.; The Darwin Tree of Life Project Consortium, ; McCarthy, S. A.; Durbin, R.
10.1101/2024.10.23.619857 — bioinformatics — Posted on 2024-10-28
687 Diabetes-Tuberculosis Comorbidity Characterized by Reduced Type-II Interferon and Elevated Th17 Responses.
Chaudhary, S.; Sravya, M.; Pahwa, F.; V, S.; Singh, P.; Chaturvedi, S.; Mohanty, D.; Dash, D.; Nanda, R.
10.1101/2024.10.24.619799 — immunology — Posted on 2024-10-28
690 Altered AP-1, RUNX, and EGR chromatin dynamics drive fibrotic lung disease
Valenzi, E.; Jia, M.; Gerges, P.; Fan, J.; Tabib, T.; Behera, R.; Zhou, Y.; Sembrat, J.; Das, J.; Benos, P. V.; Singh, H.; Lafyatis, R.
10.1101/2024.10.23.619858 — systems biology — Posted on 2024-10-28
691 Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during beta3-adrenergic stimulation in mice
Martin, C. M.; Polizzi, A.; Alquier-Bacquie, V.; Huillet, M.; Rives, C.; Dauriat, C.; Bruse, J.; Melin, V.; Naylies, C.; Lippi, Y.; Lasserre, F.; Wan, J.; Flores-Flores, R.; Bertrand-Michel, J.; Blas-Y-Estrada, F.; Rousseau-Bacquie, E.; Levade, T.; Remignon, H.; Langin, D.; Mouisel, E.; Loterzstajn, S.; Chassaing, B.; Gamet-Payrastre, L.; Guillou, H.; Ellero-Simatos, S.; Fougerat, A.; Loiseau, N.
10.1101/2024.10.24.619974 — physiology — Posted on 2024-10-28
692 Profiling of epithelial functional states and fibroblast phenotypes in hormone therapy-naive localised prostate cancer
Apostolov, E.; Roden, D. L.; Holliday, H.; Cazet, A.; Harvey, K.; Zhang, H.; Wu, S. Z.; van der Leij, S.; Selth, L. A.; Bartonicek, N.; Al-Eryani, G.; He, M.; Lundeberg, J.; Reeves, J.; Kench, J. G.; Potter, A. J.; Stricker, P. D.; Joshua, A. M.; Horvath, L. G.; Swarbrick, A.
10.1101/2024.10.23.619925 — cancer biology — Posted on 2024-10-28
694 Coordinated translational control of multiple immune checkpoints by the integrated stress response pathway in lung cancer
Thomas-Jardin, S.; Suresh, S.; Arce, A.; Novaresi, N.; Stein, E.; Thomas, L.; Lewis, C.; Ahn, C.; Evers, B. M.; Salvatierra, M. E.; Lu, W.; Khan, K.; Soto, L. M. S.; Wistuba, I.; Minna, J. D.; O'Donnell, K. A.
10.1101/2024.10.23.619897 — cancer biology — Posted on 2024-10-28
695 Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity.
Laquatra, C.; Magro, A.; Guarra, F.; Lambrughi, M.; Fracasso, G.; Bacchin, M.; Ferrone, L.; La Spina, M.; Moroni, E.; Papaleo, E.; Colombo, G.; Rasola, A.
10.1101/2024.10.24.619840 — cancer biology — Posted on 2024-10-28
696 SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironment
Zhang, W.; Lin, L.; Ying, H.; Li, N.; Zhou, X.; Yang, C.; Hu, S.; Cai, J.; Lin, A.; Cheng, Q.; Liu, Z.; Zhang, J.; Luo, P.; Wei, T.
10.1101/2024.10.23.619837 — cancer biology — Posted on 2024-10-28
701 Endothelial cell stiffness and type drive the formation of biomechanically-induced transcellular pores
Siadat, S. M.; Li, H.; Millette, B. A.; Safa, B. N.; Wong, C. A.; Bahrani Fard, M. R.; Braakman, S. T.; Tay, I.; Bertrand, J. A.; Read, A. T.; Schildmeyer, L. A.; Perkumas, K. M.; Stamer, W. D.; Overby, D. R.; Ethier, C. R.
10.1101/2024.10.23.619950 — bioengineering — Posted on 2024-10-28
706 Mechanistic insights into structure-based design of a Lyme disease subunit vaccine
Brangulis, K.; Malfetano, J.; Marcinkiewicz, A. L.; Wang, A.; Chen, Y.-L.; Lee, J.; Liu, Z.; Yang, X.; Strych, U.; Bottazzi, M. E.; Pal, U.; Hsieh, C.-L.; Chen, W.-H.; Lin, Y.-P.
10.1101/2024.10.23.619738 — immunology — Posted on 2024-10-28
707 Genetic and functional adaptations and alcohol-biased signaling in the mediodorsal thalamus of alcohol dependent mice
Martin, J. C.; Reeves, K. C.; Carter, K. A.; Davis, M.; Schneider, A.; Meade, E.; Lebonville, C. L.; Nimitvilai, S.; Hoffman, M.; Woodward, J. J.; Mulholland, P. J.; Rinker, J. A.
10.1101/2024.10.28.620696 — neuroscience — Posted on 2024-10-28
709 Reduced Folate Carrier 1 (RFC1/Slc19a1) Suppression Exacerbates Blood-Brain Barrier Breakdown in Experimental Ischemic Stroke in Adult Mice
Gurler, G.; Bozanoglu, D.; Leon, C.; Belder, N.; Sever Bahcekapili, M.; Bolbos, R.; Karatas, H.; Wiart, M.; Chauveau, F.; Yemisci, M.
10.1101/2024.10.28.620539 — neuroscience — Posted on 2024-10-28
710 The functional impact of LGI1 autoantibodies on human CA3 pyramidal neurons
Monni, L.; Kornau, H.-C.; Podesta, A.; Stumpf, A.; Kalbhenn, T.; Simon, M.; Sauvigny, T.; Onken, J.; Prüss, H.; Alle, H.; Geiger, J. R.; Holtkamp, M.; Schmitz, D.; Fidzinski, P.
10.1101/2024.10.28.620296 — neuroscience — Posted on 2024-10-28
711 Light tunes a novel long-term threat avoidance behavior
Aranda, M. L.; Min, E.; Liu, L. T.; Schipma, A. E.; Schmidt, T. M.
10.1101/2024.10.28.620706 — neuroscience — Posted on 2024-10-28
712 Reductions of Grin2a in adolescent dopamine neurons confers aberrant salience and related psychosis phenotype
Kielhold, M. L.; Jacobs, D. S.; Pacheco, A. T.; Lebowitz, J. J.; Williams, J. T.; Langdon, A. J.; Zweifel, L.; Moghaddam, B.
10.1101/2024.10.28.620713 — neuroscience — Posted on 2024-10-28
713 Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model
Yin, J.; White, J.; Khare, S.; Wu, M.; Zuberi, A. R.; Gao, M.; Nick, J. A.; Lutz, C. M.; Allen, K. D.; Nick, H. S.; Waters, M. F.
10.1101/2024.10.28.620701 — neuroscience — Posted on 2024-10-28
714 SLC4A1 MUTATIONS THAT CAUSE DISTAL RENAL TUBULAR ACIDOSIS ALTER CYTOPLASMIC PH AND CELLULAR AUTOPHAGY
Essuman, G.; Rizvi, M.; Almomani, E.; Ullah, S. A.; Hasib, S. M.; Chelangarimiyandoab, F.; Mungara, P.; Schmitt, M. J.; Hureaux, M.; Vargas-Poussou, R.; Touret, N.; Cordat, E.
10.1101/2024.10.23.619718 — physiology — Posted on 2024-10-28
715 Activating p53Y220C with a Mutant-Specific Small Molecule
Zhu, X.; Byun, W. S.; Pienkowska, D. E.; Nguyen, K. T.; Gerhartz, J.; Geng, Q.; Qiu, T.; Zhong, J.; Jiang, Z.; Wang, M.; Sarott, R. C.; Hinshaw, S. M.; Zhang, T.; Attardi, L. D.; Nowak, R. P.; Gray, N. S.
10.1101/2024.10.23.619961 — cancer biology — Posted on 2024-10-28
722 Starling murmurations under predation
Papadopoulou, M.; Hildenbrandt, H.; Storms, R. F.; Hemelrijk, C. K.
10.1101/2024.10.27.620514 — animal behavior and cognition — Posted on 2024-10-28
724 Frem2 Knockout Mice Exhibit Fraser Syndrome Phenotypes and Neonatal Lethality Due to Bilateral Renal Agenesis
Simikyan, R. G.; Zhang, X.; Strelkova, O. S.; Li, N.; Zhu, M.; Eckhard, A.; Baranov, P. Y.; Wu, X.; Lauren, R.; Indzhykulian, A. A.
10.1101/2024.10.28.620501 — developmental biology — Posted on 2024-10-28
727 Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings
Dube, J.; Foti, M.; Jaffard, S.; Latreille, V.; Frauscher, B.; Carrier, J.; Lina, J. M.
10.1101/2024.10.28.620621 — neuroscience — Posted on 2024-10-28
728 Catecholamines reduce choice history biases
de Gee, J. W.; Kloosterman, N. A.; Braun, A.; Donner, T. H.
10.1101/2024.10.28.620689 — neuroscience — Posted on 2024-10-28
729 Mechanisms and purpose of lowered action potential firing threshold in fast-spiking interneurons in the human neocortex
Bakos, E.; Tiszlavicz, A.; Szegedi, V.; Douida, A.; Furdan, S.; Welter, D.; Landry, J.; Bende, B.; Hutoczki, G.; Barzo, P.; Tamas, G.; Benes, V.; Szucs, A.; Lamsa, K.
10.1101/2024.10.28.620622 — neuroscience — Posted on 2024-10-28
730 Shifts in Naturalistic Behaviors Induced by Early Social Isolation Stress are Associated with Adult Binge-like Eating in Female Rats
Simon, T. B.; Sierra, J.; Williams, A.; Wright, G.; Rhee, A.; Horn, J.; Lou, J.; Sharafeddin, F.; Ontiveros-Angel, P.; Figueroa, J. D.
10.1101/2024.10.28.620673 — neuroscience — Posted on 2024-10-28
732 The aberrant language network dynamics in autism ages 5-40 years
Hu, Z.; Guo, X.; Yang, J.; Qu, Z.; Li, Z.; Li, J.; Gao, X.; Liu, J.; Wang, Y.; Li, W.; Li, W.; Huang, Y.; Chen, J.; Wang, X.; Yuan, B.
10.1101/2024.10.28.620600 — neuroscience — Posted on 2024-10-28
733 Inclusivity in fNIRS Studies: Quantifying the Impact of Hair and Skin Characteristics on Signal Quality with Practical Recommendations for Improvement
Yücel, M. A.; Anderson, J. E.; Rogers, D.; Hajirahimi, P.; Farzam, P.; Gao, Y.; Kaplan, R. I.; Braun, E. J.; Muqadam, N.; Duwadi, S.; Carlton, L.; Beeler, D.; Butler, L.; Carpenter, E.; Girnis, J.; Wilson, J.; Tripathi, V.; Zhang, Y.; Sorger, B.; von Lühmann, A.; Somers, D.; Cronin-Golomb, A.; Kiran, S.; Ellis, T. D.; Boas, D. A.
10.1101/2024.10.28.620644 — neuroscience — Posted on 2024-10-28
735 The claustrum is critical for maintaining working memory information
Bhattacharjee, A. S.; Huber, C.; Unsal, B.; Renfer, J.-R.; Rodriguez, I.; Carleton, A.
10.1101/2024.10.28.620649 — neuroscience — Posted on 2024-10-28
736 An anterior hypothalamic circuit gates stress vulnerability
Pennington, Z. T.; LaBanca, A. R.; Abdel-Raheim, S. D.; Bacon, M. E.; Mahmoud, A. N.; Sompolpong, P.; Baggetta, A. M.; Zaki, Y.; Ko, B.; Dong, Z.; Smith, A. C.; Kenny, P. J.; Cai, D. J.
10.1101/2024.10.28.620614 — neuroscience — Posted on 2024-10-28
737 Cortical Reactivations Modulated by Local InhibitoryCircuits Mediate Memory Consolidation
Lensjo, K. K.; Nymoen, I.; Rogge, F. S.; Tondel, K.; Sugden, A.; Shurnayte, I.; Grodem, S.; Malthe-Sorenssen, A.; Hafting, T.; Andermann, M. L.; Fyhn, M.
10.1101/2024.10.28.620563 — neuroscience — Posted on 2024-10-28
738 Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells
Gonschorek, D.; Goldin, M. A.; Oesterle, J.; Schwerd-Kleine, T.; Arlinghaus, R.; Zhao, Z.; Schubert, T.; Marre, O.; Euler, T.
10.1101/2023.12.23.572742 — neuroscience — Posted on 2024-10-28
741 A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus
Silard, C.; Germain-Amiot, N.; Poirette, P.; Legros, J.; Durao, G.; Martinais, S.; MIROUZE, N.; Augagneur, Y.
10.1101/2024.10.25.620293 — molecular biology — Posted on 2024-10-28
742 Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures
Vieira-Lara, M. A.; Warmerdam, M.; de Hulster, E. A. F.; van den Broek, M.; Daran, J.-M.; Pronk, J. T.
10.1101/2024.08.31.610600 — microbiology — Posted on 2024-10-28
743 Auditory cortex anatomy reflects multilingual phonological experience
Kepinska, O.; Dalboni da Rocha, J.; Tuerk, C.; Hervais-Adelman, A.; Bouhali, F.; Green, D.; Price, C. J.; Golestani, N.
10.1101/2023.06.16.545298 — neuroscience — Posted on 2024-10-28
744 Art's Hidden Topology: A window into human perception
Dmitruk, E.; Bajno, B.; Dreszer, J.; Bałaj, B.; Ratajczak, E.; Hajnowski, M.; Janik, R.; Kus, M.; Kadir, S. N.; Rogala, J.
10.1101/2024.10.16.618741 — neuroscience — Posted on 2024-10-28
745 Slow-wave sleep is associated with nucleus accumbens volume in elderly adults
Ban, K.; Narai, A.; Bathori, N.; Banko, E. M.; Bihari, A.; Tomacsek, V.; Kovacs, T.; Weiss, B.; Hermann, P.; Simor, P.; Vidnyanszky, Z.
10.1101/2024.10.25.620231 — neuroscience — Posted on 2024-10-28
747 Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation
Jank, L.; Singh, S. S.; Lee, J.; Dhukhwa, A.; Siavoshi, F.; Joshi, D.; Minney, V.; Gupta, K.; Ghimire, S.; Deme, P.; Schoeps, V. A.; Soman, K.; Ladakis, D.; Smith, M.; Borkowski, K.; Newman, J.; Baranzini, S. E.; Waubant, E. L.; Fitzgerald, K. C.; Mangalam, A. K.; Haughey, N.; Kornberg, M. D.; Chamling, X.; Calabresi, P. A.; Bhargava, P.
10.1101/2024.10.27.620437 — neuroscience — Posted on 2024-10-28
748 Chemosensory modulation of eye-body coordination in larval zebrafish
Sy, S. K. H.; Chan, D. C. W.; Zhang, J. J.; Lyu, J.; Feng, C.; Wang, K.; Mok, V. C. T.; Wong, K. K. Y.; Mu, Y.; Randlett, O.; Hu, Y.; Ko, H.
10.1101/2024.10.27.620486 — neuroscience — Posted on 2024-10-28
750 Acute Aerobic Exercise Enhances Associative Learning in Active but not Sedentary Individuals
Gultig, K. D.; Boele, C. P.; Roggeveen, L. E. M.; Soong, E.; Koekkoek, S. K. E.; De Zeeuw, C. I.; Boele, H.-J.
10.1101/2024.10.28.620014 — neuroscience — Posted on 2024-10-28
751 Orthogonal spectral and temporal envelope representation in auditory cortex
Takahashi, K.; Guo, T.; Yamagishi, T.; Ohshima, S.; Tsukano, H.; Horii, A.
10.1101/2024.10.28.620417 — neuroscience — Posted on 2024-10-28
753 NAD+ - and EVA1-C-dependent reversal of neurological deficits is mediated by differential alternative RNA splicing in tauopathic animal models
Ai, R.; Mao, L.; Jin, X.; Zhang, S.-q.; Pan, J.-p.; Lagartos, M. J. D.; Cao, S.-Q.; Yang, G.; Xie, C.; Kang, X.; Wang, P.; Hu, Y.; Bergersen, L. H.; Storm-Mathisen, J.; Kuroyanagi, H.; Doncel, B. E.; Gonzalez, N. V.; Chaudhry, F. A.; Wang, Z.; Zhang, Q.; Niu, Z.; Chen, G.; Luo, O. J.; Fang, E. F.
10.1101/2024.10.27.620478 — neuroscience — Posted on 2024-10-28
755 Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer's disease models
Rao, N. R.; DeGulis, O.; Nomura, T.; Lee, S.; Hark, T. J.; Dynes, J. C.; Dexter, E. X.; Dulewicz, M.; Ge, J.; Upadhyay, A.; Fornasiero, E. F.; Vassar, R.; Hanrieder, J.; Contractor, A.; Savas, J. N.
10.1101/2024.10.28.620698 — neuroscience — Posted on 2024-10-28
759 Spatial Expression of Long Non-Coding RNAs in Human Brains of Alzheimer's Disease
Ng, B.; Avey, D. R.; Lopes, K. d. P.; Fujita, M.; Tasaki, S.; Vialle, R. A.; Iatrou, A.; Tissera, S. D.; Chang, T.-H.; Xu, J.; Vyas, H.; Kearns, N. A.; Menon, V.; Gaiteri, C.; De Jager, P. L.; Bennett, D. A.; Wang, Y.
10.1101/2024.10.27.620550 — neuroscience — Posted on 2024-10-28
760 Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer
Kim, W.; Mirdita, M.; Karin, E. L.; Gilchrist, C. L. M.; Schweke, H.; Soeding, J.; Levy, E. D.; Steinegger, M.
10.1101/2024.04.14.589414 — bioinformatics — Posted on 2024-10-28
763 Improving biodiversity in Central and Eastern European domestic gardens needs regionally scaled strategies
Varga-Szilay, Z.; Barsevskis, A.; Benedek, K.; Bevk, D.; Jojczyk, A.; Kristin, A.; Ruzickova, J.; Jelaska, L. S.; Veromann, E.; Vilumets, S.; Fetyko, K.; Szovenyi, G.; Pozsgai, G.
10.1101/2024.07.12.603327 — ecology — Posted on 2024-10-28
765 Embryo-derived brain-resident macrophages sustain sleep-wake circuits
Seifinejad, A.; Bandarabadi, M.; Haddar, M.; Wundt, S.; Vassalli, A.; Tafti, M.; Monaco, G.
10.1101/2024.01.22.576653 — neuroscience — Posted on 2024-10-28
772 APOBEC3A drives metastasis of ovarian cancer by altering epithelial-to-mesenchymal transition
Devenport, J. M.; Tran, T.; Harris, B. R.; Fingerman, D. F.; DeWeerd, R. A.; Elkhidir, L.; LaVigne, D. A.; Fuh, K.; Sun, L.; Bednarski, J. J.; Drapkin, R.; Mullen, M.; Green, A. M.
10.1101/2024.10.25.620297 — cancer biology — Posted on 2024-10-28
773 Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System
Imam, F. T.; Gillespie, T. H.; Ziogas, I.; Surles-Zeigler, M. C.; Tappan, S.; Ozyurt, B.; Boline, J.; de Bono, B.; Grethe, J. S.; Martone, M. E.
10.1101/2024.10.25.620360 — bioinformatics — Posted on 2024-10-28
775 miRNA Biomarkers in Prostate Cancer: Leveraging Machine Learning for Improved Diagnostic Accuracy
Singh, S.; Pathak, A. K.; Kural, S.; Kumar, L.; Bhardwaj, M. G.; Yadav, M.; Trivedi, S.; Das, P.; Gupta, M.; Jain, G.
10.1101/2024.10.25.618146 — genomics — Posted on 2024-10-28
776 Nuclear and organelle genome assemblies of five Cucumis melo L. accessions, Ananas, Canton, PI 414723, Vedrantais and Zhimali, belonging to diverse botanical groups
Belinchon-Moreno, J.; Berard, A.; Canaguier, A.; Le-Clainche, I.; Rittener-Ruff, V.; Lagnel, J.; Hinsinger, D.; Boissot, N.; Faivre Rampant, P.
10.1101/2024.10.25.620199 — genomics — Posted on 2024-10-28
777 Long-term hybridization in a karst window reveals the genetic basis of eye loss in cavefish
Kellermeyer, R.; Seidel, C.; Redwine, W. B.; Moran, R. L.; Bertho, S.; Ornelas-Garcia, C. P.; Alegre, D.; Weaver, K. J.; Unruh, J.; Troutwine, B.; Wang, Y.; Collins, E.; Rutkowski, J.; McGaugh, S. E.; Espinasa, L.; Rohner, N.
10.1101/2024.10.25.620266 — evolutionary biology — Posted on 2024-10-28
783 Receptor-based protein binding in the supramolecular network of velvet worm slime
Hu, Z.; Baer, A.; Hering, L.; de Sena Oliveira, I.; Browne, D. C.; Guo, X.; Perrin, Q. M.; Sobota, R. M.; Hoon, S.; Mayer, G.; Harrington, M. J.; Miserez, A.
10.1101/2024.10.24.619955 — biochemistry — Posted on 2024-10-28
786 Gut microbial metabolic flux disorder in hypertension
Wenkai, L.; Zhang, Y.; Wang, M.; Lai, S.; Liu, Q.; Luo, Q.; Yang, F. l.
10.1101/2024.10.09.617349 — bioinformatics — Posted on 2024-10-28
787 Ancient genomes reveal Avar-Hungarian transformations in the 9-10th centuries CE in the Carpathian Basin
Gerber, D.; Csaky, V.; Szeifert, B.; Borbely, N.; Jakab, K.; Mezo, G.; Petkes, Z.; Szucsi, F.; Evinger, S.; Libor, C.; Racz, P.; Kiss, K.; Mende, B. G.; Szoke, B. M.; Szecsenyi-Nagy, A.
10.1101/2024.05.29.596386 — genomics — Posted on 2024-10-28
788 Age-Dependent Maturation and Rejuvenation of the Neural 3D Chromatin Interactome in Enriched Environments
Gancedo-Verdejo, J.; Urdinguio, R. G.; Tejedor, J. R.; Perez, R. F.; Penarroya, A.; Santamarina-Ojeda, P.; Roberti, A.; Kefauver, J. M.; Alvarez-Diaz, C.; Rodriguez-Santamaria, M.; Trejo, J. L.; Tomas-Daza, L.; Rovirosa, L.; Javierre, B. M.; Fernandez, A. F.; Fraga, M. F.
10.1101/2024.10.22.619383 — genomics — Posted on 2024-10-28
789 Adenine DNA methylation associated to transcription is widespread across eukaryotes
Romero Charria, P.; Navarrete, C.; Ovchinnikov, V.; Sarre, L. A.; Shabardina, V.; Casacuberta, E.; Lara-Astiaso, D.; Sebe-Pedros, A.; de Mendoza, A.
10.1101/2024.10.28.620566 — genomics — Posted on 2024-10-28
792 Modeling the velocity of evolving lineages and predicting dispersal patterns
Bastide, P.; Rocu, P.; Wirtz, J.; Hassler, G. W.; Chevenet, F.; Fargette, D.; Suchard, M. A.; Dellicour, S.; Lemey, P.; Guindon, S.
10.1101/2024.06.06.597755 — evolutionary biology — Posted on 2024-10-28
794 Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms
Suzuki, M.; Okamura, S.; Gis, T.; Sasaki, H.; Lee, S.; Yoshida, A.; Goto, S.; Matsumoto, M.; Yamawaki, M.; Miyazaki, T.; Nakagawa, T.; Ikawa, M.; Kamitani, W.; Takekawa, S.; Yamanishi, K.; Ebina, H.
10.1101/2024.03.03.582873 — microbiology — Posted on 2024-10-28
795 Antibiotic resistance detection and concomitant species identification of ESKAPE pathogens by proteomics
Blumenscheit, C.; Pfeifer, Y.; Werner, G.; John, C.; Layer-Nicolaou, F.; Schneider, A.; Lasch, P.; Doellinger, J.
10.1101/2024.09.09.612008 — microbiology — Posted on 2024-10-28
796 Tracing active members in microbial communities by BONCAT and click chemistry-based enrichment of newly synthesised proteins
Hellwig, P.; Kautzner, D.; Heyer, R.; Dittrich, A.; Wibberg, D.; Busche, T.; Winkler, A.; Reichl, U.; Benndorf, D.
10.1101/2024.08.27.609880 — microbiology — Posted on 2024-10-28
801 Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity.
Cox, D. J.; Connolly, S. A.; Maoldomhnaigh, C. O.; Brugman, A. A.; Thomas, O. S.; Duffin, E.; Gogan, K. M.; O Gallchobhair, O.; Murphy, D. M.; O'Rourke, S. A.; O'Connell, F.; Nadarajan, P.; Phelan, J. J.; Gleeson, L. E.; Basdeo, S. A.; Keane, J.
10.1101/2024.03.20.585747 — immunology — Posted on 2024-10-28
802 Improving the monitoring of the invasive Blue Crab (Callinectes sapidus): combining environmental DNA and citizen observations
Delrieu-Trottin, E.; Bianic, M.; Miaud, C.; Garcia, M.; Arnal, V.; Hocde, R.; Cochet, C.; Barre, N.; Cornil, L.; Manel, S.
10.1101/2024.10.24.620022 — ecology — Posted on 2024-10-28
806 Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar
Miraldo, A.; Sundh, J.; Iwaszkiewicz-Eggebrecht, E.; Buczek, M.; Goodsell, R.; Johansson, H.; Fisher, B. L.; Raharinjanahary, D.; Rajoelison, E. T.; Ranaivo, C.; Randrianandrasana, C. E.; Rafanomezantsoa, J.-J.; Manoharan, L.; Granqvist, E.; van Dijk, L. J. A.; Ahlberg, L.; Ahlen, D.; Aspebo, M.; Aström, S.; Bellviken, A.; Bergman, P.-E.; Björklund, S.; Björkman, M. P.; Deng, J.; Desborough, L.; Dolff, E.; Eliasson, A.; Elmquist, H.; Emanuelsson, H. Z. S.; Erixon, R.; Fahlen, L.; Frogner, C.; Fürst, P.; Grabs, A.; Grudd, H.; Guasconi, D.; Gunnarsson, M.; Häggqvist, S.; Hed, A.; Hörnströ
10.1101/2024.10.24.619818 — ecology — Posted on 2024-10-28
807 A comparative study of navigation behaviours in ants
Shen, X.; Wystrach, A.; Gelin, U.; Charles-Dominique, T.; Tomlinson, K. W.
10.1101/2024.10.24.619962 — ecology — Posted on 2024-10-28
808 Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures
Banellis, L.; Nikolova, N.; Brandholdt, M.; Vejlo, M.; Fardo, F.; Smallwood, J.; Allen, M. G.
10.1101/2024.10.25.620252 — neuroscience — Posted on 2024-10-28
810 I-SVVS: Integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data
Dang, T.; Fuji, Y.; Kumaishi, K.; Usui, E.; Kobori, S.; Sato, T.; Toda, Y.; Sakurai, K.; Yamasaki, Y.; Tsujimoto, H.; Hirai, M. Y.; Ichihashi, Y.; Iwata, H.
10.1101/2023.08.18.553796 — bioinformatics — Posted on 2024-10-28
811 Dominance reversal protects large-effect resistance polymorphisms in temporally varying environments
Karageorgi, M.; Lyulina, A. S.; Bitter, M. C.; Lappo, E.; Greenblum, S. I.; Mouza, Z. K.; Tran, C. T.; Huynh, A. V.; Oken, H.; Schmidt, P.; Petrov, D. A.
10.1101/2024.10.23.619953 — evolutionary biology — Posted on 2024-10-28
812 Transcriptional profiles of murine oligodendrocyte precursor cells across the lifespan
Heo, D.; Kim, A. A.; Neumann, B.; Doze, V. N.; Xu, Y. K. T.; Mironova, Y. A.; Slosberg, J.; Goff, L. A.; Franklin, R. J. M.; Bergles, D. E.
10.1101/2024.10.27.620502 — neuroscience — Posted on 2024-10-28
816 Dissecting the Contribution of Transposable Elements to Interphase Chromosome Structure
Shi, L.; Zhen, X.; Babarinde, I. A.; Fu, X.; Ma, G.; Huang, Z.; Sun, L.; Zhou, X.; He, J.; Strunnikov, A.; Hutchins, A. P.
10.1101/2024.10.25.620372 — cell biology — Posted on 2024-10-27
817 Systematic standardization of organ-on-a-chip under controlled flow conditions: use case with Caki-1 and A549 cell lines
Balsa-Diaz, A.; Vazquez-Vazquez, L.; Ferreiro-Vila, E.; Rivas-Meizoso, L.; Martinez, A. L.; Brea, J.; Loza, M. I.; Perez Rodriguez, S.; Sinde, E.; Alvarez, E.; Rodino-Janeiro, B. K.
10.1101/2024.10.26.619288 — cell biology — Posted on 2024-10-27
818 Development of novel flavonoid senolytics through phenotypic drug screening and drug design
Zhang, L. J.; Salekeen, R.; Soto-Palma, C.; He, Y.; Elsallabi, O.; Hughes, B.; Nunes, A.; Xu, W.; Zhang, B.; Mohamed, A.; Mcgowan, S.; Angelini, L.; O'Kelly, R.; Kamenecka, T. M.; Niedernhofer, L. J.; Robbins, P. D.
10.1101/2024.10.27.620529 — cell biology — Posted on 2024-10-27
821 IGF2 mediates Hippo signaling to control liver size
Zhong, Z.; Jin, R.; Zhong, Y.; Zhang, L.; Chen, D.; Jiao, Z.; Zhou, F.; Zhu, R.; Wu, J.; Dong, R.; Dong, K.; Lan, F.; Wang, Y.; Guan, K.-L.; Yu, F.-X.
10.1101/2024.10.27.620455 — cell biology — Posted on 2024-10-27
822 Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion
Lu, Y.; Walji, T.; Ravaux, B.; Pandey, P.; Yang, C.; Li, B.; Delgermaa Luvsanjav, D.; Lam, K. H.; Zhang, R.; Luo, Z.; Zhou, C.; Habela, C. W.; Snapper, S.; Li, R.; Goldhamer, D. J.; Schmidtke, D. W.; Pan, D.; Svitkina, T. M.; Chen, E.
10.1101/2024.10.25.620345 — cell biology — Posted on 2024-10-27
823 The phase separation landscape of genome-wide genetic perturbations
Heidenreich, M.; Mathur, S.; Shu, T.; Xie, Y.; Sriker, D.; Dubreuil, B.; Holt, L. J.; Levy, E. D.
10.1101/2024.10.25.620319 — cell biology — Posted on 2024-10-27
826 Hypusinated and unhypusinated isoforms of eIF5A exert distinct effects in models of pancreas development and function
Anderson, C. M.; Kulkarni, A.; Maier, B.; Huang, F.; Figatner, K.; Chakraborty, A.; Pratuangtham, S.; May, S. C.; Tersey, S. A.; Anderson, R. M.; Mirmira, R. G.
10.1101/2024.10.27.620489 — cell biology — Posted on 2024-10-27
827 Eye-movement artifact correction in infant EEG
Srishyla, D.; Webb, S.; Elsabbagh, M.; O'Reilly, C.; BASIS team, Center for Brain and Cognitive Development, London,UK,
10.1101/2024.03.19.585723 — neuroscience — Posted on 2024-10-27
828 Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs long-term memory by fragmenting sleep
Yan, L.; Wu, L.; Wiggin, T. D.; Su, X.; Yan, W.; Li, H.; Li, L.; Lu, Z.; Li, Y.; Meng, Z.; Guo, F.; Li, F.; Griffith, L.; Liu, C.
10.1101/2023.10.23.563499 — neuroscience — Posted on 2024-10-27
831 Circular RNA AEBP2: A novel regulator in dendritic cell development
Zhou, Q.; Wang, B.; Li, S.; Greasley, A.; Min, W.; Vareki, S. M.; Zheng, X.
10.1101/2024.10.23.619919 — immunology — Posted on 2024-10-27
833 A pangenome and pantranscriptome of hexaploid oat
Avni, R.; Kamal, N.; Bitz, L.; Jellen, E.; Bekele, W.; Angessa, T.; Auvinen, P.; Bitz, O.; Boyle, B.; Canales, F.; Carlson, C. H.; Chapman, B.; Chawla, H. S.; Chen, Y.; Copetti, D.; Dang, V.; Eichten, S.; Esvelt Klos, K.; Fenn, A.; Fiebig, A.; Fu, Y.-B.; Gundlach, H.; Gupta, R.; Haberer, G.; He, T.; Herrmann, M. H.; Himmelbach, A.; Howarth, C.; Hu, H.; Isidro y Sanchez, J.; Itaya, A.; Jannink, J.-L.; JIA, Y.; Kaur, R.; Knauft, M.; Langdon, T.; Lux, T.; Marmon, S.; Marosi, V.; Mayer, K. F. X.; Michel, S.; Nandety, R. S.; Nilsen, K.; Paczos-Grzeda, E.; Pasha, A.; Prats, E.; Provart, N. J.; Ravag
10.1101/2024.10.23.619697 — genomics — Posted on 2024-10-27
834 Benchmarking of Low Coverage Sequencing Workflows for Precision Genotyping in Eggplant
Baraja-Fonseca, V.; Arrones, A.; Vilanova, S.; Plazas, M.; Prohens, J.; Bombarely, A.; Gramazio, P.
10.1101/2024.10.24.619843 — genomics — Posted on 2024-10-27
836 The geometry of gametic dispersal in a flying mammal, Rhinolophus hipposideros
Brazier, T.; Zarzoso-Lacoste, D.; Lehnen, L.; Jan, P.-L.; Puechmaille, S. J.; Petit, E. J.
10.1101/2024.10.24.620000 — evolutionary biology — Posted on 2024-10-27
837 Enhanced Prediction of Seafloor Ecological State Using 16S Nanopore Sequencing
Philip, M.; Nilsen, T.; Majaneva, S.; Pettersen, R.; Stokkan, M.; Ray, J. L.; Keeley, N.; rudi, k.; Snipen, L.-G.
10.1101/2024.10.25.620171 — ecology — Posted on 2024-10-27
838 Bacterial inoculation manipulates the coral epigenome
Barno, A. R.; Villela, H. D.; Cardoso, P. M.; Garcia, F. C.; Cui, G.; Delgadillo-Ordonez, N.; Rosado, A. S.; Thomas, T.; Aranda, M.; Voolstra, C. R.; Peixoto, R.
10.1101/2024.10.27.620496 — molecular biology — Posted on 2024-10-27
839 Integrated hepatic ferroptosis gene signature dictates pathogenic features of ferroptosis
Matsumoto, T.; Nita, A.; Kanamori, Y.; Maeda, A.; Yasuda-Yoshihara, N.; Mima, K.; Okabe, H.; Imai, K.; Hayashi, H.; Matsuoka, Y.; Nagaoka, K.; Nakayama, K. I.; Sugihara, Y.; Tanaka, Y.; Baba, H.; Moroishi, T.
10.1101/2024.10.27.620461 — molecular biology — Posted on 2024-10-27
841 Targeting ADORA-PDE10 cAMP Microdomain: A Novel Therapeutic Approach for Pulmonary Hypertension
Valasarajan, C.; Hesami, G.; Maroli, G.; Cherian, A. V.; Laria, J. C.-p.; Laria, N. C. -P.; Wietelmann, A.; Gnatzy-Feik, L.; Rosenkranz, S.; Savai, R.; Seeger, W.; Pullamsetti, S. S.
10.1101/2024.10.27.616460 — molecular biology — Posted on 2024-10-27
842 Virus Entry is a Major Determinant of HCMV Latency in Monocytes
Kitsberg, Y.; Nachshon, A.; arazi, t.; Fisher, T.; Wainstein, A.; Finkel, Y.; Stern-Ginossar, N.; Schwartz, M.
10.1101/2024.10.26.619803 — microbiology — Posted on 2024-10-27
844 Functional characterization and optimization of protein expression in Treponema denticola shuttle plasmids
Goetting-Minesky, M. P.; Godovikova, V.; Saraithong, P.; Rickard, A. H.; Crawley, B. R.; Agolli, S. M.; Fenno, J. C.
10.1101/2024.10.27.620309 — microbiology — Posted on 2024-10-27
845 FRUCTOSE ACTIVATES A STRESS RESPONSE SHARED BY METHYLGLYOXAL AND HYDROGEN PEROXIDE IN STREPTOCOCCUS MUTANS
Walker, A. R.; Pham, D. N.; Noeparvar, P.; Peterson, A. M.; Lipp, M. K.; Lemos, J. A.; Zeng, L.
10.1101/2024.10.26.620100 — microbiology — Posted on 2024-10-27
848 Identification and characterization of UBA5 inhibitors
Singh, V.; Wan, Y.; Ahmed, T. R.; Wang, S.-Y.; Samrat, S. K.; Li, Z.; Sinha, S.; Gan, L.; Li, H.
10.1101/2024.10.25.620379 — biochemistry — Posted on 2024-10-27
852 CRISPR screening by AAV episome-sequencing (CrAAVe-seq) is a highly scalable cell type-specific in vivo screening platform
Ramani, B.; Rose, I. V. L.; Teyssier, N.; Pan, A.; Danner-Bocks, S.; Sanghal, T.; Yadanar, L.; Tian, R.; Ma, K.; Palop, J. J.; Kampmann, M.
10.1101/2023.06.13.544831 — genomics — Posted on 2024-10-27
853 Coexistence in Periodic Environments
Scott, A. M.; Bieg, C.; McMeans, B. M.; McCann, K.
10.1101/2023.02.24.529749 — ecology — Posted on 2024-10-27
854 Long-lived chondroprogenitors are generated by fetal-limb Gli1+ cells and are replenished upon mosaic cell-cycle arrest in the cartilage
Qu, X.; Razmara, E.; H'ng, C. H.; Vinu, K. K.; Martelotto, L. G.; Zethoven, M.; Rossello, F. J.; Johnstone, R. W.; Amarasinghe, S. L.; Powell, D. R.; Rosello-Diez, A.
10.1101/2024.07.29.603524 — developmental biology — Posted on 2024-10-27
855 Ketamine reverses chronic stress-induced behavioral changes via the expression of Ca2+-permeable AMPA receptors in mice
Flowers, J. C.; Vetter, P. E.; Wiles, M. J.; Roh, S. H.; Black, E. R.; Bouckova, E.; Wustrau, M. H.; Lee, R.; Lee, S.-H.; Kim, S.
10.1101/2024.10.07.616991 — neuroscience — Posted on 2024-10-27
860 An integrated view of the structure and function of the human 4D nucleome
The 4D Nucleome Consortium, ; Dekker, J.; Oksuz, B. A.; Zhang, Y.; Wang, Y.; Minsk, M. K.; Kuang, S.; Yang, L.; Gibcus, J. H.; Krietenstein, N.; Rando, O.; Xu, J.; Janssens, D. H.; Henikoff, S.; Kukalev, A.; Willemin, A.; Winick-Ng, W.; Kempfer, R.; Pombo, A.; Yu, M.; Kumar, P.; Zhang, L.; Belmont, A. S.; Sasaki, T.; van Schaik, T.; Brueckner, L.; Peric-Hupkes, D.; van Steensel, B.; Wang, P.; Chai, H.; Kim, M.; Ruan, Y.; Zhang, R.; Quinodoz, S. A.; Bhat, P.; Guttman, M.; Zhao, W.; Chien, S.; Liu, Y.; Venev, S. V.; Plewczynski, D.; Irastorza Azcarate, I.; Szabo, D.; Thieme, C. J.; Szczepinska,
10.1101/2024.09.17.613111 — genomics — Posted on 2024-10-27
863 Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation
Husain, M. A.; Smith, R.; Sorge, R. E.; Kaimari, A.; Si, Y.; Hassan, A. Z.; Guha, A.; Smith, K. A.; Cardozo, C. P.; DeBerry, J. J.; Anadrabi, S.; Nabors, L. B.; Filippova, N.; Webb, C. K.; King, P. H.
10.1101/2024.10.25.620341 — neuroscience — Posted on 2024-10-27
864 Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses
Goble, K.; Mehta, A.; Guilbaud, D.; Fessler, J.; Chen, J.; Nenad, W.; Cope, O.; Chen, D.; Dennis, W.; Gurumurthy, N.; Wang, Y.; Shukla, K.; Brunk, E.
10.1101/2024.10.23.619848 — cancer biology — Posted on 2024-10-27
865 Motor Clustering Enhances Kinesin-driven Vesicle Transport
Jiang, R.; Feng, Q.; Nong, D.; Kang, Y. J.; Sept, D.; Hancock, W. O.
10.1101/2024.10.23.619892 — biophysics — Posted on 2024-10-27
866 Secreted Clever-1 Modulates T Cell Responses and Impacts Cancer Immunotherapy Efficacy
Prince, S.; Viitala, M.; Sjöroos, R.; Bendes, A. A.; Rannikko, J. H.; Patten, D. A.; di Benedetto, I.; Tyni, L.; Figueiredo, C. R.; Koskivuo, I.; Salminen, T. A.; Shetty, S.; Hollmen, M.
10.1101/2024.10.23.619796 — immunology — Posted on 2024-10-27
869 NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma
Lindblad, K. E.; Donne, R.; Liebling, I.; Bresnahan, E.; Barcena-Varela, M.; Lozano, A.; Park, E.; Giotti, B.; Burn, O.; Fiel, M. I.; Bravo-Cordero, J. J.; Tsankov, A. M.; Lujambio, A.
10.1101/2024.10.23.619856 — cancer biology — Posted on 2024-10-27
870 Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms
Bowden, S.; Brislinger-Engelhardt, M. M.; Hansen, M.; Temporal Plo, A.; Weber, D.; Haegele, S. L.; Lorenz, F.; Litwin, T.; Kreutz, C.; Walentek, P.
10.1101/2024.10.27.620464 — developmental biology — Posted on 2024-10-27
871 Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish
Lopez-Blanch, L.; Rodriguez-Marin, C.; Mantica, F.; Iniguez, L. P.; Permanyer, J.; Kita, E. M.; Mackensen, T.; Codina-Tobias, M.; Romero-Ferrero, F.; Fernandez-Albert, J.; Cuadrado, M.; Bustelo, X. R.; de Polavieja, G.; Irimia, M.
10.1101/2024.10.23.619860 — molecular biology — Posted on 2024-10-27
872 Low Intestinal Doses of Botulinum Neurotoxins types A and B favour infection by Salmonella and Shigella without the flaccid paralysis of botulism
Fabris, F.; Brun, P.; Megighian, A.; Bernabe', G.; Castagliuolo, I.; Drigo, I.; Bano, L.; Lista, F.; Bernardini, M. L.; Montecucco, C.; Rossetto, O.
10.1101/2024.10.26.620416 — neuroscience — Posted on 2024-10-27
873 Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep
Meijer, E. J.; Mueller, M.; Krone, L. B.; Yamagata, T.; Hoerder-Suabedissen, A.; Wilcox, S.; Alfonsa, H.; Chakrabarty, A.; Guidi, L.; Oliver, P.; Vyazovskiy, V. V.; Molnar, Z.
10.1101/2024.10.26.620399 — neuroscience — Posted on 2024-10-27
874 Effects of one-night partial sleep deprivation on perivascular space volume fraction: Findings from the Stockholm Sleepy Brain Study
Custer, R. M.; Lynch, K. M.; Barisano, G.; Herting, M. M.; Akerstedt, T.; Nilsonne, G.; Ahmadi, H.; Choupan, J.
10.1101/2024.10.26.620382 — neuroscience — Posted on 2024-10-27
876 Bystander base editing interferes with visual function restoration in Leber congenital amaurosis
Lee, S.-H.; Wu, J.; Im, D.; Hwang, G.-H.; Jeong, Y. K.; Jiang, H.; Lee, S. J.; Jo, D. H.; Goddard, W. A.; Kim, J. H.; Bae, S.
10.1101/2024.10.23.619839 — genetics — Posted on 2024-10-27
878 Stoichiometry of HIV-1 Envelope Glycoprotein Protomers with Changes That Stabilize or Destabilize the Pretriggered Conformation
Zhang, Z.; Anang, S.; Wang, Q.; Nguyen, H. T.; Chen, H.-C.; Chiu, T.-J.; Yang, D.; Smith, A. B.; Sodroski, J. G.
10.1101/2024.10.25.620268 — microbiology — Posted on 2024-10-27
879 Lipid hydrogen isotope compositions primarily reflect growth water in the model archaeon Sulfolobus acidocaldarius
Harris, C. M.; Kopf, S.; Rhim, J. H.; Cobban, A.; Elling, F. J.; Feng, X.; McFarlin, J.; Weber, Y.; Zhang, Y.; Zhou, A.; Batther, H.; Pearson, A.; Leavitt, W. D.
10.1101/2024.10.24.620110 — microbiology — Posted on 2024-10-27
881 Aberrant iron deposition in the multiple sclerosis spinal cord relates to neurodegeneration
Pisa, M.; Lockhart, A.; Angell, T.; Avery, A.; Waldman, A.; Pansieri, J.; Rodriguez, C.; Duarte, T.; Dhari, Z.; Bailey, M.; Hametner, S.; Drakesmith, H.; Hofer, M.; Limbaeck, C.; DeLuca, G. C.
10.1101/2024.10.25.619794 — neuroscience — Posted on 2024-10-27
883 DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans
Sehgal, R.; Borrus, D.; Kasamato, J.; Armstrong, J. F.; Gonzalez, J.; Markov, Y.; Priyanka, A.; Smith, R.; Carreras, N.; Dwaraka, V. B.; DNA aging biomarkers community, ; Longevity interventional studies community, ; Higgins-Chen, A.
10.1101/2024.10.22.619522 — systems biology — Posted on 2024-10-27
884 Regulation of Crassulacean Acid Metabolism at the protein level in the CAM plant Kalanchoë laxiflora
Schiller, K.; Janshoff, S.; Zenker, S.; Viehöver, P.; Hartwell, J.; Eirich, J.; Finkemeier, I.; Bräutigam, A.
10.1101/2024.10.25.620298 — plant biology — Posted on 2024-10-27
886 CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance
Kheir, E.; Libergoli, M.; Metti, S.; Jensen, J. B.; Wang, J.; Jessen, N.; Florio, F.; Murganti, F.; Di Savino, S.; Belicchi, M.; Villa, C.; Vissing, K.; Verma, M.; Giordani, L.; Bonaldo, P.; Torrente, Y.; Farup, J.; Biressi, S.
10.1101/2024.10.25.619970 — cell biology — Posted on 2024-10-27
887 Avian-specific Salmonella enterica Serovar Gallinarum transition to endemicity is accompanied by localized resistome and mobilome interaction
Jia, C.; Huang, C.; Zhou, H.; Zhou, X.; Wang, Z.; Siddique, A.; Kang, X.; Cao, Q.; Huang, Y.; He, F.; Li, Y.; Yue, M.
10.1101/2024.07.26.605275 — microbiology — Posted on 2024-10-27
889 Dopamine transmission in the anterior insula shapes the neural coding of anxiety
COUDERC, Y.; DHANI REDDY, T.; VARDIERO, G.; GARG, A.; RICCI, D.; D'ALMEIDA, M.; NICOLAS, C.; HABCHI, T.; WU, Y. K.; GJORGJIEVA, J.; Li, Y.; VALJENT, E.; BEYELER, A.
10.1101/2024.10.25.620186 — neuroscience — Posted on 2024-10-27
891 African origin haplotype protective for Alzheimer's disease in APOEϵ4 carriers: exploring potential mechanisms
Bertholim-Nasciben, L.; Nuytemans, K.; Van Booven, D.; Rajabli, F.; Moura, S.; Ramirez, A. M.; Dykxhoorn, D. M.; Wang, L.; Scott, W. K.; Davis, D. D.; Vontell, R. T.; McInerney, K. F.; Cuccaro, M. L.; Byrd, G. S.; Haines, J. L.; Gearing, M.; Adams, L. D.; Pericak-Vance, M. A.; ADSP (Alzheimers Disease Sequencing Project), ; Young, J. I.; Griswold, A. J.; Vance, J. M.
10.1101/2024.10.24.619909 — genetics — Posted on 2024-10-27
897 Slow oscillation-spindle coupling predicts sequence-based language learning
Cross, Z. R.; Helfrich, R. F.; Corcoran, A. W.; Dede, A. J. O.; Kohler, M. J.; Coussens, S.; Zou-Williams, L.; Schlesewsky, M.; Gaskell, M. G.; Knight, R. T.; Bornkessel-Schlesewsky, I.
10.1101/2020.02.13.948539 — neuroscience — Posted on 2024-10-27
902 Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Towards a national plant health risk analysis for Cameroon and Ethiopia
Mouafo-Tchinda, R.; Etherton, B.; Plex Sula, A.; Andrade-Piedra, J.; Ogero, K.; Omondi, B. A.; McEwan, M.; Tene Tayo, P.; Harahagazwe, D.; Cherinet, M.; Gebeyehu, S.; Sperling, L.; Garrett, K. A.
10.1101/2024.02.12.580019 — ecology — Posted on 2024-10-27
904 CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
Samelson, A. J.; Ariqat, N.; McKetney, J.; Rohanitazangi, G.; Parra Bravo, C.; Bose, R.; Travaglini, K. J.; Lam, V. L.; Goodness, D.; Dixon, G.; Marzette, E.; Jin, J.; Tian, R.; Tse, E.; Abskharon, R.; Pan, H.; Carroll, E. C.; Lawrence, R. E.; Gestwicki, J. E.; Eisenberg, D.; Kanaan, N. M.; Southworth, D. R.; Gross, J. D.; Gan, L.; Swaney, D. L.; Kampmann, M.
10.1101/2023.06.16.545386 — cell biology — Posted on 2024-10-26
905 Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
Worrell, J. C.; Hargrave, K. E.; Finney, G. E.; Hansell, C.; Cole, J. J.; Singh Niijar, J.; Morton, F. R.; Pingen, M.; Purnell, T.; Mitchelson, K.; Brennan, E.; Allan, J.; Ilia, G.; Herder, V.; Kennedy Dietrich, C.; Doncheva, Y.; Jamieson, N.; Palmarini, M.; MacLeod, M. K.
10.1101/2024.07.20.604410 — immunology — Posted on 2024-10-26
907 The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output
Trevisan, A. J.; Han, K.; Chapman, P.; Kulkarni, A. S.; Hinton, J. M.; Ramirez, C.; Klein, I.; Gatto, G.; Gabitto, M. I.; Menon, V.; Bikoff, J. B.
10.1101/2024.09.18.613279 — neuroscience — Posted on 2024-10-26
909 Dysregulation of FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis
Casey, A. K.; Stewart, N. M. S.; Zaidi, N.; Gray, H. F.; Fields, H. A.; Sakurai, M.; Pinzon-Arteaga, C. A.; Evers, B. M.; Wu, J.; Orth, K.
10.1101/2024.10.25.620287 — physiology — Posted on 2024-10-26
910 Empirically establishing drug exposure records directly from untargeted metabolomics data
Zhao, H. N.; Kvitne, K. E.; Brungs, C.; Mohan, S.; Charron-Lamoureux, V.; Bittremieux, W.; Tang, R.; Schmid, R.; Lamichhane, S.; El Abiead, Y.; Andalibi, M. S.; Mannochio-Russo, H.; Ambre, M.; Avalon, N. E.; Bryant, M.; Caraballo-Rodriguez, A. M.; Maya, M. C.; Chin, L.; Ellis, R. J.; Franklin, D.; Girod, S.; Gomes, P. W. P.; Hansen, L.; Heaton, R.; Iudicello, J. E.; Jarmusch, A. K.; Khatib, L.; Letendre, S.; Magyari, S.; McDonald, D.; Mohanty, I.; Cumsille, A.; Moore, D. J.; Rajkumar, P.; Ross, D. H.; Sapre, H.; Shahneh, M. R. Z.; Thomas, S. P.; Tribelhorn, C.; Tubb, H. M.; Walker, C.; Wang, C
10.1101/2024.10.07.617109 — bioinformatics — Posted on 2024-10-26
912 Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes
Banse, S. A.; Sedore, C. A.; Coleman-Hulbert, A.; Johnson, E.; Onken, B.; Hall, D.; Segerdell, E.; Jackson, E. G.; Song, Y.; Osman, H. C.; Xue, J.; Basttistoni, E.; Guo, S.; Foulger, A.; Achanta, M.; Sheikh, M.; Fitzgibbon, T.; Willis, J. H.; Woodruff, G. C.; Driscoll, M.; Lithgow, G.; Phillips, P. C.
10.1101/2024.10.23.619838 — genetics — Posted on 2024-10-26
913 Exploring mechanisms of change in a Southern Ocean fishery with a co-produced network model
Ward, D.; Hill, N.; Melbourne-Thomas, J.; Welsford, D.; Arangio, R.; McNeill, M.; Wotherspoon, S.; Ziegler, P.; Corney, S.
10.1101/2024.10.23.619600 — ecology — Posted on 2024-10-26
914 Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions
Sarkar, S.; Sharma, H.; Hosen, S. Y.; Ladke, J. S.; Balasubramanian, D.; Raran-Kurussi, S.; Bhandari, R.; Jaiswal, M.
10.1101/2023.03.26.534266 — cell biology — Posted on 2024-10-26
916 Identifying simultaneous inhibition of riboflavin metabolism and MEK as a novel therapeutic strategy for pancreatic cancer
Ooshio, T.; Satoh, Y.; Jiang, H.; Liu, T.; Fujii, K.; Ishikawa, T.; Igarashi, K.; Saitoh, K.; Kato, K.; Mashima, T.; Jin, S.; Matoba, K.; Mack, M.; Osawa, T.; Seimiya, H.; Soga, T.; Sonoshita, M.
10.1101/2024.10.23.619807 — cancer biology — Posted on 2024-10-26
918 Generative Models Validation via Manifold Recapitulation Analysis
Lazzaro, N.; Leonardi, G.; Marchesi, R.; Datres, M.; Saiani, A.; Tessadori, J.; Granados, A.; Henriksson, J.; Chierici, M.; Jurman, G.; Sales, G.; Tebaldi, T.
10.1101/2024.10.23.619602 — bioinformatics — Posted on 2024-10-26
919 AlphaBridge: tools for the analysis of predicted macromolecular complexes
Alvarez Salmoral, D.; Borza, R.; Xie, R.; Joosten, R. P.; Hekkelman, M.; Perrakis, A.
10.1101/2024.10.23.619601 — bioinformatics — Posted on 2024-10-26
921 Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its cluster cofactor and active site required for DNA repair
Trasvina-Arenas, C. H.; Dissanayake, U. C.; Tamayo, N.; Hashemian, M.; Lin, W.-J.; Demir, M.; Hoyos-Gonzalez, N.; Fisher, A. J.; Cisneros, G. A.; Horvath, M.; David, S. S.
10.1101/2024.10.25.620305 — biochemistry — Posted on 2024-10-26
923 A sequence-specific RNA acetylation catalyst
Thalalla Gamage, S.; Howpay Manage, S.; Sas-Chen, A.; Nir, R.; Burkhart, B. W.; Jhulki, I.; Link, C. N.; Penikalapati, M. S.; Jones, J. E.; Iyer, L. M.; Aravind, L.; Santangelo, T. J.; Schwartz, S.; Meier, J. L.
10.1101/2024.10.25.620255 — biochemistry — Posted on 2024-10-26
927 Unraveling transposable element-mediated regulatory landscape in diverse human immune cells
Du, C.; Fan, H.; Jiang, J.; Yang, J.; Chen, S.; Vorobyeva, N. E.; Zhu, C.; Mao, L.; Li, C.; Li, Y.; Bao, W.; Sun, M.-a.
10.1101/2024.10.24.620010 — genomics — Posted on 2024-10-26
930 Mitochondrial cardiolipin metabolism controlled by tafazzin enables ferroptosis
Wohlfarter, Y.; Hagenbuchner, J.; Horzum, U.; Oemer, G.; Winter, A.; Seifert, M.; Schwaerzler, J.; Kokot, J.; Hernansanz Agustin, P.; Juric, V.; Garcia Suoza, L. F.; Talasz, H.; Enriquez Dominguez, J. A.; Farhan, H.; Weiss, G.; Zschocke, J.; Keller, M. A.
10.1101/2024.10.25.620299 — molecular biology — Posted on 2024-10-26
934 Biotic interactions shape infection outcomes in Arabidopsis
Mahmoudi, M.; Almario, J.; Hu, Y.; Tenzer, L.-m.; Nieselt, K.; Kemen, E.
10.1101/2024.10.25.620230 — microbiology — Posted on 2024-10-26
935 Malat1 regulates female Th2 cell cytokine expression through controlling early differentiation and response to IL2
Gwynne, M.; West, K. A.; van Dongen, S.; Kourtzelis, I.; Coverley, D.; Teichmann, S. A.; James, K. R.; Hewitson, J. P.; Lagos, D.
10.1101/2024.10.23.619648 — immunology — Posted on 2024-10-26
936 In vitro metabolic interaction network of a rationally designed nasal microbiota community
Bonillo-Lopez, L.; Rouam el Khatab, O.; Obregon-Gutierrez, P.; Florez-Sarasa, I.; Correa-Fiz, F.; Sibila, M.; Aragon, V.; Kochanowski, K.
10.1101/2024.10.23.619785 — systems biology — Posted on 2024-10-26
937 Identification and characterization of UBA5 inhibitors
Singh, V.; Wan, Y.; Ahmed, T. R.; Wang, S.-Y.; Samrat, S. K.; Li, Z.; Sinha, S.; Gan, L.; Li, H.
10.1101/2024.10.25.620379 — biochemistry — Posted on 2024-10-26
938 Deep structural analysis of rhamnogalacturonan-I (RG-I) in Arabidopsis reveals new insights into pectin diversity
Zhang, L.; Vlach, J.; Black, I. M.; Archer-hartmann, S. A.; Heiss, C.; Azadi, P.; Urbanowicz, B. R.
10.1101/2024.10.25.620358 — biochemistry — Posted on 2024-10-26
947 Ybx1 guides C/EBPα and cBAF chromatin-remodeling complex to promote adipogenic gene expression in steatotic hepatocytes
Jordan, J. M.; Qiao, J.; Zou, C.; Stenseels, S.; Haczeyni, F.; Fraim, A.; Cisneros, A. M.; de Jong, Y. P.; Ersoy, B.
10.1101/2024.10.25.620017 — developmental biology — Posted on 2024-10-26
952 Brain-like learning with exponentiated gradients
Cornford, J.; Pogodin, R.; Ghosh, A.; Sheng, K.; Bicknell, B.; Codol, O.; Clark, B. A.; Lajoie, G.; Richards, B.
10.1101/2024.10.25.620272 — neuroscience — Posted on 2024-10-26
955 Reward invigorates isometric gripping actions
Marbaker, R. M.; Schmad, R. C.; Al-Ghamdi, R. A.; Sukumar, S.; Ahmed, A. A.
10.1101/2024.10.25.620324 — neuroscience — Posted on 2024-10-26
956 Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures
Banellis, L.; Nikolova, N.; Brandholdt, M.; Vejlo, M.; Fardo, F.; Smallwood, J.; Allen, M. G.
10.1101/2024.10.25.620252 — neuroscience — Posted on 2024-10-26
960 Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting homeostatic astrocyte function
Abiero, A. R.; Gladding, J. M.; Iredale, J.; Drury, H. R.; Manning, E. E.; Dayas, C. V.; Dhungana, A.; Ganesan, K.; Turner, K.; Becchi, S.; Kendig, M. D.; Nolan, C.; Balleine, B. W.; Castorina, A.; Cole, L.; Clemens, K.; Bradfield, L.
10.1101/2024.10.24.620154 — animal behavior and cognition — Posted on 2024-10-26
965 Spatiotemporal dynamics of primary and motile cilia throughout lung development
Spurgin, S.; Nguimtsop, A. M.; Chaudhry, F. N.; Michki, S.; Salvador, J.; Iruela-Arispe, M. L.; Zepp, J.; Mukhopadhyay, S.; Cleaver, O.
10.1101/2024.10.25.620342 — developmental biology — Posted on 2024-10-26
966 Irx3/5 define the cochlear sensory domain and regulate vestibular and cochlear sensory patterning in the mammalian inner ear
Liu, Y.; Qin, T.; Weng, X.; Leung, B.; So, K. K. H.; Wang, B.; Feng, W.; Marsolais, A.; Josselyn, S.; Huang, P.; Fritzsch, B.; Hui, C.-C.; Sham, M. H.
10.1101/2024.10.24.620152 — developmental biology — Posted on 2024-10-26
967 Abl kinases regulate FGF signaling independent of Crk phosphorylation to prevent Peters anomaly
Wu, H.; Mao, Y.; Wang, Q.; Yu, H.; Bouaziz, M.; Makrides, N.; Koleske, A. J.; Radice, G.; Zhang, X.
10.1101/2024.10.24.619064 — developmental biology — Posted on 2024-10-26
968 Planarians Develop Radiotolerance to Recurrent Ionizing Radiation Exposure
Barghouth, P. G.; Ziman, B.; Maciel, E. I.; Karabinis, P.; Rojas, S.; Flores, N. M.; Pfister, E.; Oviedo, N. J.
10.1101/2024.10.25.620371 — developmental biology — Posted on 2024-10-26
972 Testing the Tests: Using Connectome-Based Predictive Models to Reveal the Systems Standardized Tests and Clinical Symptoms Are Reflecting
Samardzija, A.; Shen, X.; Luo, W.; Greene, A. S.; Mehta, S.; Tokoglu, F.; Arora, J.; Woods, S.; Katz, R.; Sanacora, G.; Srihari, V. H.; Scheinost, D.; Constable, R. T.
10.1101/2024.10.24.619737 — neuroscience — Posted on 2024-10-26
973 Imaging synaptic density in ageing and Alzheimer's Disease with -SynVesT-1
Giorgio, J.; Soleimani-Meigooni, D. N.; Janabi, M.; Baker, S.; Chen, X.; Toueg, T. N.; Weimer, R.; Zinnhardt, B.; Green, A.; Rabinovici, G. D.; Jagust, W.
10.1101/2024.10.23.619941 — neuroscience — Posted on 2024-10-26
976 Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucoma.
Thompson, J. L.; McCool, S.; Smith, J. C.; Schaal, V.; Pendyala, G.; Yelamanchili, S.; Van Hook, M. J.
10.1101/2024.10.25.619907 — neuroscience — Posted on 2024-10-26
977 Sex Differences in Contextual Extinction Learning After Single Binge-Like EtOH Exposure in Adolescent C57BL/6J Mice
Cardona-Jordan, K. M.; Lay-Rivera, X. X.; Bracho-Rincon, D.; Gonzalez-Bermejo, R.; Alvarado-Monefeldt, G. L.; Gonzales-del Toro, J. P.; Esquillin-Rodriguez, C.; Lloret-Torres, M. E.; Velazquez-Marrero, C.
10.1101/2024.10.25.620195 — neuroscience — Posted on 2024-10-26
979 Multisensory integration in Peripersonal Space indexes consciousness states in sleep and disorders of consciousness
Bertoni, T.; Ricci, G.; Johr, J.; Donno, B.; Cataldi, J.; Fellrath, J.; Stephan, A.; Foglia, C.; Lecci, S.; Dauvin, F.; Lopez Da Silva, M.; Galigani, M.; Pozeg, P.; Dunet, V.; De Lucia, M.; Noel, J. P.; Magosso, E.; Diserens, K.; Siclari, F.; Serino, A.
10.1101/2024.10.25.619776 — neuroscience — Posted on 2024-10-26
980 High-precision neurofeedback-guided meditation training optimises real-world self-guided meditation practice for well-being
Ganesan, S.; Van Dam, N.; Kamboj, S. K.; Tsuchiyagaito, A.; Sacchet, M. D.; Misaki, M.; Moffat, B. A.; Lorenzetti, V.; Zalesky, A.
10.1101/2024.10.25.618656 — neuroscience — Posted on 2024-10-26
981 Alternatives to Friction Coefficient: Fine Touch Perception Relies on Frictional Instabilities
Derkaloustian, M.; Bhattacharyya, P.; Ngo, T. T.; Cashaback, J.; Medina, J.; Dhong, C. B.
10.1101/2024.10.25.620351 — neuroscience — Posted on 2024-10-26
983 The Interaction of UBR4, LRP1, and OPHN1 in Refractory Epilepsy: Drosophila Model to Investigate the Oligogenic Effect on Epilepsy
Huang, R.-N.; Luo, S.-Y.; Huang, T.; Li, X.-S.; Zhou, F.-C.; Li, L.-Y.; Chen, Z.-R.; Chen, S.-Q.; Tang, B.; Qiao, J.-D.
10.1101/2024.10.25.620163 — neuroscience — Posted on 2024-10-26
984 EEG-VLM Toolbox: Extending voxel-based lesion mapping to multi-dimensional EEG data
Hardstone, R.; Ostrowski, L.; Dusang, A. N.; Lopez-Larraz, E.; Jesser, J.; Cash, S. S.; Cramer, S. C.; Hochberg, L. R.; Ramos-Murguialday, A.; Lin, D. J.
10.1101/2024.10.25.620269 — neuroscience — Posted on 2024-10-26
991 Shared and unique lifetime stressor characteristics and brain networks predict adolescent anxiety and depression
Qu, Y.; Chopra, S.; Qu, S.; Cocuzza, C. V.; Labache, L.; Bauer, C. C. C.; Morfini, F.; Whitfield-Gabrieli, S.; Slavich, G. M.; Joormann, J.; Holmes, A. J.
10.1101/2024.10.25.620373 — neuroscience — Posted on 2024-10-26
992 Idiosyncrasy and generalizability of contraceptive- and hormone-related functional connectomes across the menstrual cycle
Bottenhorn, K. L.; Salo, T.; Jacobs, E. G.; Pritschet, L.; Taylor, C. M.; Herting, M. M.; Laird, A. R.
10.1101/2024.10.24.620112 — neuroscience — Posted on 2024-10-26
993 Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation
Husain, M. A.; Smith, R. H.; Sorge, R. E.; Kaimari, A. H.; Si, Y. H.; Hassan, A. Z.; Guha, A. H.; Smith, K. A.; Cardozo, C. P.; DeBerry, J. J.; Anadrabi, S.; Nabors, L. B.; Filippova, N.; Webb, C. K.; King, P. H.
10.1101/2024.10.25.620341 — neuroscience — Posted on 2024-10-26
994 String-pulling by the common marmoset
Bertrand, M.; Karkuszewski, M.; Kersten, R.; Orban de Xivry, J.-J.; Pruszynski, J. A.
10.1101/2024.10.25.620352 — neuroscience — Posted on 2024-10-26
995 Dysfunction of the episodic memory network in the Alzheimer's disease cascade
Lattmann-Grefe, R.; Vockert, N.; Machts, J.; Suksangkharn, Y.; Yakupov, R.; Schuetze, H.; Glanz, W.; Incesoy, E.; Butryn, M.; Luesebrink, F.; Schmid, M.; Stark, M.; Kleineidam, L.; Spottke, A.; Coenjaerts, M.; Brosseron, F.; Fliessbach, K.; Schneider, A.; Dechent, P.; Hetzer, S.; Scheffler, K.; Ramirez, A.; Laske, C.; Sodenkamp, S.; Altenstein, S.; Schneider, L.-S.; Gref, D.; Spruth, E. J.; Lohse, A.; Schott, B. H.; Wiltfang, J.; Kilimann, I.; Goerss, D.; Rostamzadeh, A.; Priller, J.; Peters, O.; Hellmann-Regen, J.; Teipel, S.; Jessen, F.; Maass, A.; Ziegler, G.; Duezel, E.
10.1101/2024.10.25.620237 — neuroscience — Posted on 2024-10-26
996 The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies
Francis, B.; Gozashti, L.; Costello, K.; Kasahara, T.; Harringmeyer, O. S.; Lilue, J.; Helmy, M.; Kato, T.; Czechanski, A.; Quail, M.; Bonner, I.; Dawson, E.; Smith, A. F.; Reinholdt, L.; Adams, D. J.; Keane, T. M.
10.1101/2024.10.24.619615 — genomics — Posted on 2024-10-26
997 Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages
Egan, M. S.; O'Rourke, E. A.; Mageswaran, S. K.; Zuo, B.; Martynyuk, I.; Demissie, T.; Hunter, E. N.; Bass, A. R.; Chang, Y.-W.; Brodsky, I. E.; Shin, S.
10.1101/2023.07.17.549348 — microbiology — Posted on 2024-10-26
1000 Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis
Kume, M.; Koguchi-Yoshioka, H.; Nakai, S.; Matsumura, Y.; Tanemura, A.; Yokoi, K.; Matsuda, S.; Nakamura, Y.; Otani, N.; Taminato, M.; Tomita, K.; Kubo, T.; Wataya-Kaneda, M.; Kumanogoh, A.; Fujimoto, M.; Watanabe, R.
10.1101/2024.04.02.587777 — immunology — Posted on 2024-10-26
1004 NF-κB Epigenetic Attractor Landscape Drives Breast Cancer Heterogeneity
Lopes, F. J. P.; Pires, B. R. B.; Lima, A. A. B.; Binato, R.; Abdelhay, E.
10.1101/2024.07.10.602798 — systems biology — Posted on 2024-10-26
1005 Optimizing protein production in the One-Pot PURE system: insights into reaction composition and expression efficiency
Zhang, Y.; Deveikis, M.; Qiu, Y.; Björn, L.; Martinez, Z. A.; Chou, T.-F.; Freemont, P.; Murray, R. M.
10.1101/2024.06.19.599772 — synthetic biology — Posted on 2024-10-26
1007 Anemia and tissue hypoxia are major determinants of malarial hypelactatemia
Georgiadou, A.; Yoon, C. E.; Yu, H.; Pearson, W. H.; Ueno, A.; Ebmeier, S.; Larrouy-Maumus, G.; Cunnington, A. J.
10.1101/2024.10.22.619641 — pathology — Posted on 2024-10-26
1008 Eco-evolutionary Guided Pathomic Analysis to Predict DCIS Upstaging
Xiao, Y.; Elmasry, M.; Bai, J.; Chen, A.; Chen, Y.; Jackson, B.; Johnson, J. O.; Gillies, R. J.; Prasanna, P.; Chen, C.; Damaghi, M.
10.1101/2024.06.23.600274 — cancer biology — Posted on 2024-10-26
1009 ATP-release pannexin channels are gated by lysophospholipids
Henze, E.; Burkhardt, R. N.; Fox, B. W.; Schwertfeger, T. J.; Gelsleichter, E.; Michalski, K.; Kramer, L.; Lenfest, M.; Boesch, J. M.; Lin, H.; Schroeder, F. C.; Kawate, T.
10.1101/2023.10.23.563601 — biophysics — Posted on 2024-10-26
1014 Identification of nuclear pore proteins at plasmodesmata
Schladt, T. M.; Miras, M.; Ejike, J. O.; Pottier, M.; Xi, L.; Restrepo, A.; Nakamura, M.; Puetz, N.; Haensch, S.; Gao, C.; Engelhorn, J.; Dickmanns, M.; Davis, G.; Dalal, A.; Gombos, S.; Lange, R.; Simon, R.; Schulze, W. X.; Frommer, W. B.
10.1101/2024.09.02.610746 — cell biology — Posted on 2024-10-26
1016 A Meta-analysis of the known Global Distribution and Host Range of the Ralstonia Species Complex
Lowe-Power, T.; Avalos, J.; Bai, Y.; Charco Munoz, M.; Chipman, K.; Elmgreen, V. N.; Prasad, N.; Williams, D.; Ramirez, B.; Sandhar, A.; Tom, C. E.
10.1101/2020.07.13.189936 — microbiology — Posted on 2024-10-26
1017 B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
Cho, S. H.; Jones, M. A.; Meyer, K.; Anderson, D. M.; Chetyrkin, S.; Calcutt, M. W.; Caprioli, R. M.; Semenkovich, C. F.; Boothby, M. R.
10.1101/2024.10.17.618760 — immunology — Posted on 2024-10-26
1018 Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
Worrell, J. C.; Hargrave, K. E.; Finney, G. E.; Hansell, C.; Cole, J. J.; Singh Niijar, J.; Morton, F. R.; Pingen, M.; Purnell, T.; Mitchelson, K.; Brennan, E.; Allan, J.; Ilia, G.; Herder, V.; Kennedy Dietrich, C.; Doncheva, Y.; Jamieson, N.; Palmarini, M.; MacLeod, M. K.
10.1101/2024.07.20.604410 — immunology — Posted on 2024-10-26
1021 Biomimic opto-nanobiointerface enables multiscale biomodulation
Mueller, C.; Zhang, Y.; Meng, L.; Kalatanova, A.; Madsen, J. G.; Klompmaker, K. K.; Jakobsen, T. S.; Joergensen, A. C.; Askou, A. L.; Huang, G.; Li, W.; Davidsen, R. S.; Bek, T.; Hatzakis, N. S.; Corydon, T. J.; Leinonen, H. O.; Tian, B.; Dong, M.; Chen, M.
10.1101/2024.10.23.619813 — bioengineering — Posted on 2024-10-26
1023 Evaluation of extraction solvents for untargeted metabolomics to decipher the dissolved organic matter of Antarctic cryoconite holes
Mundhe, S. D.; Maiti, S.; Sanyal, A.; Kadoo, N. Y.; Dhotre, D.; Barvkar, V. T.; Shaikh, S. A.; Antony, R.; Paul, D.
10.1101/2024.04.29.591772 — microbiology — Posted on 2024-10-26
1026 CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
Sun, Y.; Kronenberg, N. M.; Sethi, S. K.; Dash, S. N.; Kovalik, M. E.; Sempowski, B.; Strickland, S.; Raina, R.; Sperati, C. J.; Tian, X.; Ishibe, S.; Hall, G.; Gather, M. C.
10.1101/2024.10.22.619513 — biophysics — Posted on 2024-10-26
1027 Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope
Corbett, A. D.; Horsell, D.; Watters, T.; Ghasemi, M.; Henderson, L.; Mohanan, S.; Mullenbroich, C.; Bub, G.; Burton, F.; Smith, G. L.
10.1101/2024.09.09.611998 — biophysics — Posted on 2024-10-26
1028 A deep profile of gene expression across 18 human cancers
Qiu, W.; Dincer, A. B.; Janizek, J.; Celik, S.; Pittet, M.; Naxerova, K.; Lee, S.-I.
10.1101/2024.03.17.585426 — bioinformatics — Posted on 2024-10-26
1029 Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets
Nicholson, T. M.; Tokihiro, J. C.; Tu, W.-c.; Khor, J. W.; Lee, U. N.; Berthier, E.; Amory, J. K.; Walsh, T. J.; Muller, C. H.; Theberge, A. B.
10.1101/2024.05.09.593416 — bioengineering — Posted on 2024-10-26
1030 A simple action reduces high fat diet intake and obesity in mice
Barrett, M. R.; Pan, Y.; Murrell, C.; Karolczak, E. O.; Wang, J.; Fang, L.; Thompson, J. M.; Chang, Y.-H.; Casey, E.; Czarny, J.; So, W. L.; Reichenbach, A.; Stark, R.; Taghipourbibalan, H.; Penna, S. R.; McCullough, K. B.; Westbrook, S.; Matikainen-Ankeny, B.; Cazares, V. A.; Delevich, K.; Fobbs, W.; Maloney, S.; Sutton Hickey, A.; McCutcheon, J. E.; Andrews, Z.; Creed, M.; Krashes, M. J.; Kravitz, A. V.
10.1101/2024.10.01.615599 — animal behavior and cognition — Posted on 2024-10-26
1032 The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy
POPLI, P.; Oestreich, A. K.; MAURYA, V. K.; ROWEN, M. N.; Masand, R.; Holtzman, M.; Zhang, Y.; P Lydon, J.; Shizuo Akira, P.; Moley, K.; Kommagnani, R.
10.1101/2024.03.19.585812 — developmental biology — Posted on 2024-10-26
1034 Endothelial features along the pulmonary vascular tree in chronic thromboembolic pulmonary hypertension: distinctive or shared facets?
Verhaegen, J.; Willems, L.; Wagenaar, A.; Spreuwers, R.; Dahdah, N.; Aversa, L.; Verbelen, T.; Delcroix, M.; Quarck, R.
10.1101/2024.02.27.582290 — cell biology — Posted on 2024-10-26
1035 In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity
Hagan, N. B.; Inaku, C.; Kunder, N.; White, T.; Iraguha, T.; Meyer, A.; Pauken, K.; Schenkel, J. M.
10.1101/2024.08.10.607414 — immunology — Posted on 2024-10-26
1036 Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons
Di Bartolomei, G.; Ortiz, R.; Schreiner, D.; Falkner, S.; Creemers, E. E.; Scheiffele, P.
10.1101/2023.12.06.570345 — neuroscience — Posted on 2024-10-26
1037 Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus
O'Keeffe, M.; Booker, S.; Walsh, D.; Li, M.; Henley, C.; Simoes de Oliveira, L.; Liu, M.; Wang, X.; Banqueri-Lopez, M.; Ridley, K.; Dissanyake, K.; Martinez-Gonzales, C.; Craigie, K.; Vasoya, D.; Leah, T.; He, X.; Hume, D. A.; Duguid, I.; Nolan, M.; Qiu, J.; Wyllie, D. J.; Dando, O.; Gonzales-Sulsar, A.; Gan, J.; Pridans, C.; Kind, P. C.; Hardingham, G. E.
10.1101/2024.09.06.611614 — neuroscience — Posted on 2024-10-26
1038 Transcription factors SlMYB41, SlMYB92 and SlWRKY71 regulate gene expression in tomato exodermis
Jo, L.; Buti, S.; Artur, M. S.; Kluck, R. M. C.; Canto Pastor, A.; Brady, S.; Kajala, K.
10.1101/2024.08.29.610307 — plant biology — Posted on 2024-10-26
1039 The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma
Lightfuss, O. B.; Kumar, P.; Li, L.; Shastri, T.; Newsam, A. D.; Manara, P.; Alaoui, A. Y.; Parets, D. E. H.; Younes, P. A.; Chahar, D.; Arumov, A.; Coughlin, C. A.; Williams, I. P.; Fattakhov, N.; Martinez, A. B.; Landgren, O.; Schurer, S. C.; Lemmon, V.; Maura, F.; Bilbao, D.; Feng, Y.; Al-Ali, H.; Schatz, J. H.
10.1101/2024.10.21.619489 — cancer biology — Posted on 2024-10-26
1040 Conformational changes of the ABC Transporter BmrA Depend on Membrane Curvature
Damm, A.; Paik, S.-J.; Sadhu, R. K.; Di Cicco, A.; Manzi, J.; Castellana, M.; Margeat, E.; Dahan, M.; Sens, P.; Levy, D.; Bassereau, P.
10.1101/2024.01.24.577054 — biophysics — Posted on 2024-10-26
1041 Nicheformer: a foundation model for single-cell and spatial omics
Schaar, A. C.; Tejada-Lapuerta, A.; Palla, G.; Gutgesell, R.; Halle, L.; Minaeva, M.; Vornholz, L.; Dony, L.; Drummer, F.; Bahrami, M.; Theis, F. J.
10.1101/2024.04.15.589472 — bioinformatics — Posted on 2024-10-26
1044 Human genetic ancestry, Mycobacterium tuberculosis diversity and tuberculosis disease severity in Dar es Salaam, Tanzania
Zwyer, M.; Xu, Z. M.; Ross, A.; Hella, J.; Sasamalo, M.; Rotival, M.; Hiza, H.; Rutaihwa, L. K.; Borrell, S.; Reither, K.; Fellay, J.; Portevin, D.; Quintana-Murci, L.; Gagneux, S.; Brites, D.
10.1101/2024.08.10.607244 — evolutionary biology — Posted on 2024-10-26
1045 Passive accumulation of alkaloids in inconspicuously colored frogs refines the evolutionary paradigm of acquired chemical defenses
Tarvin, R. D.; Coleman, J. L.; Donoso, D. A.; Betancourth-Cundar, M.; Lopez-Hervas, K.; Gleason, K. S.; Sanders, J. R.; Smith, J. M.; Ron, S. R.; Santos, J. C.; Sedio, B. E.; Cannatella, D. C.; Fitch, R.
10.1101/2024.05.13.593697 — evolutionary biology — Posted on 2024-10-26
1050 Astrocyte regional specialization is shaped by postnatal development
Schroeder, M. E.; McCormack, D. M.; Metzner, L.; Kang, J.; Li, K. X.; Yu, E.; Levandowski, K. M.; Zaniewski, H.; Zhang, Q.; Boyden, E.; Krienen, F. M.; Feng, G.
10.1101/2024.10.11.617802 — neuroscience — Posted on 2024-10-26
1051 "Micro-offline gains" convey no benefit for motor skill learning
Das, A.; Karagiorgis, A.; Diedrichsen, J.; Stenner, M.-P.; Azanon, E.
10.1101/2024.07.11.602795 — neuroscience — Posted on 2024-10-26
1052 Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group
Cimmino, D. B.; Zabriskie, B.; Luke, S.; Gutman, B.; Isaev, D.; Alpert, K.; Glahn, D.; Rodrigue, A.; Kelly, S.; Pearlson, G.; Calhoun, V.; Ehrlich, S.; Andreassen, O.; Tordesillas-Gutierrez, D.; Crespo-Facorro, B.; Satterthwaite, T.; Gur, R.; Gur, R.; Spalletta, G.; Piras, F.; Donohoe, G.; McDonald, C.; Pomarol-Clotet, E.; Salvador, R.; Karuk, A.; Voineskos, A.; Kochunov, P.; Borgwardt, S.; Agartz, I.; Jonsson, E.; Kircher, T.; Stein, F.; Brosch, K.; Nenadic, I.; Iasevoli, F.; Pontillo, G.; de Bartolomeis, A.; Barone, A.; Ciccarelli, M.; Di Giorgio, A.; Brunetti, A.; Cocozza, S.; Tranfa, M.; J
10.1101/2024.10.24.619733 — neuroscience — Posted on 2024-10-26
1053 Whole-body connectome of a segmented annelid larva
Veraszto, C.; Jasek, S.; Gühmann, M.; Bezares-Calderon, L. A.; Williams, E.; Shahidi, R.; Jekely, G.
10.1101/2024.03.17.585258 — neuroscience — Posted on 2024-10-26
1054 Executive Resources Shape the Effects of Language Predictability Across the Adult Lifespan
Schuckart, M. M.; Martin, S.; Tune, S.; Schmitt, L.-M.; Hartwigsen, G.; Obleser, J.
10.1101/2024.05.08.592872 — neuroscience — Posted on 2024-10-26
1055 The FIP 1.0 Data Set: Highly Resolved Annotated Image Time Series of 4,000 Wheat Plots Grown in Six Years
Roth, L.; Boss, M.; Kirchgessner, N.; Aasen, H.; Aguirre-Cuellar, B. P.; Akiina, P. P. A.; Anderegg, J.; Gajardo Castillo, J.; Chen, X.; Corrado, S.; Cybulski, K.; Keller, B.; Kortstee, S. G.; Kronenberg, L.; Liebisch, F.; Nousi, P.; Oppliger, C.; Perich, G.; Pfeifer, J.; Yu, K.; Storni, N.; Tschurr, F.; Volpi, M.; Treier, S.; Zellweger, H.; Zumsteg, O.; Hund, A.; Walter, A.
10.1101/2024.10.04.616624 — plant biology — Posted on 2024-10-26
1058 TissueViewer: A Web-Based Multiplexed Image Viewer
van IJzendoorn, D. G. P.; Matusiak, M.; West, R. B.; van de Rijn, M.
10.1101/2024.06.21.600100 — bioinformatics — Posted on 2024-10-26
1059 Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine
Schoenle, A.; Guiglielmoni, N.; Mainz, T.; Greve, C.; Hamadou, A. B.; Heermann, L.; Borcherding, J.; Waldvogel, A.-M.
10.1101/2024.04.22.590508 — genomics — Posted on 2024-10-26
1061 Relative fire-proneness of land cover types in the Brazilian Atlantic Forest
Adorno, B. F.; Piratelli, A. A.; Hasui, E.; Ribeiro, M. C.; Vaz, P. G.
10.1101/2024.07.21.604452 — ecology — Posted on 2024-10-26
1062 Syntaxin11 Deficiency Inhibits CRAC Channel Priming To Suppress Cytotoxicity And Gene Expression In FHLH4 Patient T Lymphocytes.
Vig, M.; Datta, S.; Gupta, A.; Jagetiya, K. M.; Tiwari, V. R.; Yamashita, M.; Ammann, S.; Shahrooei, M.; Yande, A. R.; Sowdhamini, R.; Dani, A.; Prakriya, M.
10.1101/2024.10.25.620144 — cell biology — Posted on 2024-10-25
1063 An IFN-STAT1-CYBB Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk During Aspergillus fumigatus Infection.
Guo, Y.; Aufiero, M. A.; Mills, K. A. M.; Grassmann, S. A.; Kim, H.; Zumbo, P.; Gjonbalaj, M.; Billips, A.; Mar, K. B.; Yu, Y.; Betel, D.; Sun, J. C.; Hohl, T. M.
10.1101/2024.10.24.620079 — immunology — Posted on 2024-10-25
1064 Dopamine transmission in the anterior insula shapes the neural coding of anxiety
COUDERC, Y.; DHANI REDDY, T.; VARDIERO, G.; GARG, A.; RICCI, D.; D'ALMEIDA, M.; NICOLAS, C.; HABCHI, T.; WU, Y. K.; GJORGJIEVA, J.; VALJENT, E.; BEYELER, A.
10.1101/2024.10.25.620186 — neuroscience — Posted on 2024-10-25
1066 Auditory working memory mediates the relationship between musicianship and auditory stream segregation
Liu, M.; Arseneau-Bruneau, I.; Franch, M. F.; Latorre, M.-E.; Samuels, J.; Issa, E.; Payumo, A.; Rahman, N.; Loureiro, N.; Leung, T. C. M.; Nave, K. M.; von Handorf, K. M.; Hoddinott, J. D.; Coffey, E. B. J.; Grahn, J.; Zatorre, R. J.
10.1101/2024.10.24.619127 — neuroscience — Posted on 2024-10-25
1067 Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk
Ajunwa, C. C.; Zhang, J.; Collin, G.; Keshavan, M. S.; Tang, Y.; Zhang, T.; Li, H.; Shenton, M. E.; Stone, W. S.; Wang, J.; Niznikiewicz, M.; Whitfield-Gabrieli, S.
10.1101/2024.10.25.620271 — neuroscience — Posted on 2024-10-25
1073 Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome
Yarbro, J. M.; Han, X.; Dasgupta, A.; Yang, K.; Liu, D.; Shrestha, H.; Zaman, M.; Wang, Z.; Yu, K.; Lee, D. G.; Vanderwall, D.; Niu, M.; Sun, H.; Xie, B.; Chen, P.-C.; Jiao, Y.; Zhang, X.; Wu, Z.; Fu, Y.; Li, Y.; Yuan, Z.-F.; Wang, X.; Poudel, S.; Vagnerova, B.; He, Q.; Tang, A.; Ronaldson, P.; Chang, R.; YU, G.; Liu, Y.; Peng, J.
10.1101/2024.10.25.620263 — biochemistry — Posted on 2024-10-25
1075 Population genomics and molecular epidemiology of wheat powdery mildew in Europe
Jigisha, J.; Ly, J.; Minadakis, N.; Freund, F.; Kunz, L.; Piechota, U.; Akin, B.; Balmas, V.; Ben-David, R.; Bencze, S.; Bourras, S.; Bozzoli, M.; Cotuna, O.; Couleaud, G.; Cseplo, M.; Czembor, P.; Desiderio, F.; Dörnte, J.; Dreiseitl, A.; Feechan, A.; Gadaleta, A.; Gauthier, K.; Giancaspro, A.; Giove, S. L.; Handley-Cornillet, A.; Hubbard, A.; Karaoglanidis, G.; Kildea, S.; Koc, E.; Liatukas, Z.; Lopes, M. S.; Mascher, F.; McCabe, C.; Miedaner, T.; Martinez-Moreno, F.; Nellist, C. F.; Okon, S.; Praz, C.; Sanchez-Martin, J.; Sarateanu, V.; Schulz, P.; Schwartz, N.; Seghetta, D.; Solis Martel,
10.1101/2024.10.24.619980 — evolutionary biology — Posted on 2024-10-25
1076 Genic and phylogenomic discordances reveal conflicting hybridization episodes in temperate Loliinae grasses
Moreno-Aguilar, M. F.; Viruel, J.; Calderon, D.; Arnelas, I.; Sanchez-Rodriguez, A.; Chen, W.; Ospina, J. C.; Martinez-Sagarra, G.; Devesa, J. A.; Stewart, A.; Catalan, P.
10.1101/2024.10.25.620283 — evolutionary biology — Posted on 2024-10-25
1078 Impaired erythroid maturation in murine embryos upon loss of the preeclampsia-associated serine protease prostasin
Di Carlo, S.; Bastos, A. S.; Castelblanco, M.; Auberson, M.; Rumpler, M. D.; Tournier, M.; Sommer, L.; Naveiras, O.; Hummler, E.
10.1101/2024.10.25.620248 — developmental biology — Posted on 2024-10-25
1079 The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA
Carrick, B. H.; Crittenden, S. L.; Linsley, M.; Costa Dos Santos, S. J.; Wickens, M.; Kimble, J.
10.1101/2024.10.25.620246 — developmental biology — Posted on 2024-10-25
1080 The E3 Ubiquitin Ligase Trip12 attenuates Wnt9a/Fzd9b signaling during hematopoietic stem cell development
Ensing, J.; Ide, A. D.; Gilliland, C.; Tsurho, V.; Caza, I.; Stratman, A. N.; Lanning, N. J.; Grainger, S.
10.1101/2024.10.25.620301 — cell biology — Posted on 2024-10-25
1081 Sphingolipid imbalance aggravates fibrillar Tau-induced endomembrane rigidification and rupture
Tittelmeier, J.; Sandhof, C. A.; Martin, N.; El-Kabarity, D.; Ngonza-Nito, S.-B.; Melki, R.; Nussbaum-Krammer, C.
10.1101/2024.10.24.619578 — cell biology — Posted on 2024-10-25
1082 G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation.
Tricot, S.; Siberchicot, C.; Bontemps, I.; Desmaze, C.; Kratassiouk, G.; Vandamme, M.; Pinna, G.; Radicella, J. P.; Lenaers, G.; Lebeau, J.; Campalans, A.
10.1101/2024.10.24.619985 — cell biology — Posted on 2024-10-25
1086 A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus
Silard, C.; Germain-Amiot, N.; Poirette, P.; Legros, J.; Durao, G.; Martinais, S.; MIROUZE, N.; Augagneur, Y.
10.1101/2024.10.25.620293 — molecular biology — Posted on 2024-10-25
1087 Establishing the green algae Chlamydomonas incerta as a platform for recombinant protein production
Kang, K.; do Espirito Santo, E.; Diaz, C. J.; Oliver, A.; Saxton, L.; May, L.; Mayfield, S.; Dutra Molino, J. V.
10.1101/2024.10.25.618925 — microbiology — Posted on 2024-10-25
1090 Principles and Operation of Virtual Brain Twins
Hashemi, M.; Depannemaecker, D.; Saggio, M.; Triebkorn, P.; Rabuffo, G.; Fousek, J.; Ziaeemehr, A.; Sip, V.; Athanasiadis, A.; Breyton, M.; Woodman, M.; Wang, H.; Petkoski, S.; Sorrentino, P.; Jirsa, V.
10.1101/2024.10.25.620245 — neuroscience — Posted on 2024-10-25
1091 Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model
Lentini, V.; Uras, G.; Manca, A.; El Faqir, M. A.; Lucas Del Pozo, S.; Deiana, N.; Cao, G.; Schapira, A. H.; Pantaleo, A.
10.1101/2024.10.25.620204 — neuroscience — Posted on 2024-10-25
1092 Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties
Mohan, H. M.; Fernandez, M. G.; Huang, C.; Lin, R.; Ryou, J.; Seyfried, D.; Grotewold, N.; Whiteley, A. M.; Barmada, S.; Basrur, V.; Mosalaganti, S.; Paulson, H. L.; Sharkey, L. M.
10.1101/2024.10.24.620053 — neuroscience — Posted on 2024-10-25
1093 Microglial states determine lesion dynamics in multiple sclerosis
van den Bosch, A. M.; Khoo, J. H.; Lu, Z.; Liang, H.; Wever, D.; Pu, L.; Eggen, B.; Uhlen, M.; Smolders, J.; Hamann, J.; Shang, Z.; Mulder, J.; Huitinga, I.
10.1101/2024.10.25.620251 — neuroscience — Posted on 2024-10-25
1094 High-throughput biodiversity surveying sheds new light on the brightest of insect taxa
Iwaszkiewicz-Eggebrecht, E.; Goodsell, R. M.; Bengsson, B.-A.; Mutanen, M.; Klinth, M.; van Dijk, L. J. A.; Łukasik, P.; Miraldo, A.; Andresson, A. F.; Tack, A. J. M.; Roslin, T.; Ronquist, F.
10.1101/2024.10.25.620209 — zoology — Posted on 2024-10-25
1096 TFE3 fusion proteins drive oxidative metabolism, ferroptosis resistance and general RNA synthesis in translocation renal cell carcinoma
Davidson, I.; Malouf, G. G.; Helleux, A.; Davidson, G.; Lallement, A.; Haller, A.; Michel, I.; Fadloun, A.; Thibault-Carpentier, C.; Su, X.; Lindner, V.; Tricard, T.; Lang, H.; Tannir, N. M.
10.1101/2024.10.24.620047 — cancer biology — Posted on 2024-10-25
1098 Site of breast cancer metastasis is independent of single nutrient levels
Abbott, K. L.; Subudhi, S.; Ferreira, R.; Gültekin, Y.; Steinbuch, S. C.; Munim, M. B.; Honeder, S. E.; Kumar, A. S.; Ramesh, D. L.; Wu, M.; Hansen, J. A.; Sivanand, S.; Riedmayr, L. M.; Duquette, M.; Ali, A.; Henning, N.; Shevzov-Zebrun, A.; Gourgue, F.; Barbeau, A. M.; Waite, M.; Kunchok, T.; Ferraro, G. B.; Do, B. T.; Spanoudaki, V.; Sanchez-Rivera, F. J.; Jin, X.; Church, G. M.; Jain, R. K.; Vander Heiden, M. G.
10.1101/2024.10.24.616714 — cancer biology — Posted on 2024-10-25
1107 Single-cell transcriptomics reveal diverging pathobiology and opportunities for precision targeting in scleroderma-associated versus idiopathic pulmonary arterial hypertension
Tuhy, T.; Coursen, J. C.; Graves, T.; Patatanian, M.; Cherry, C. M.; Niedermeyer, S. E.; Khan, S. L.; Rosen, D. T.; Croglio, M. P.; Elnashar, M.; Kolb, T. M.; Mathai, S. C.; Damico, R. L.; Hassoun, P. M.; Shimoda, L.; Suresh, K.; Aldred, M. A.; Simpson, C. E.
10.1101/2024.10.25.620225 — bioinformatics — Posted on 2024-10-25
1108 The Mag-Click-Capture-Release Technology for Selective Capture and Release of Hepatocyte-Derived Extracellular Vesicles as Biomarkers for Liver Disease
Booijink, R.; Mentink, A.; Jansen, L.; Mentink, S.; van Rein, B.; Geraets, L.; Scholten, J.; Brusse, M.; Fu, S.; Boonstra, A.; Bansal, R.
10.1101/2024.10.25.620223 — bioengineering — Posted on 2024-10-25
1113 NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts)
de Visser, M. C.; France, J.; McCartney-Melstad, E.; Bucciarelli, G. M.; Theodoropoulos, A.; Shaffer, H. B.; Wielstra, B.
10.1101/2024.10.25.620290 — genomics — Posted on 2024-10-25
1115 MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants
Han, S.; Sun, X.; Sloofman, L.; Satterstrom, F. K.; Wang, G.; Liang, L.; Knoblauch, N.; Zhao, S.; Liu, Y.; Shen, W.; Nguyen, H. T.; He, X.
10.1101/2024.10.24.620131 — genetics — Posted on 2024-10-25
1118 Experimental evolution of Drosophila without its microbiome
Malwade, A.; Koner, A.; Vibishan, B.; Gadkari, C.; Saini, S.; Khodake, V.; Dey, S.
10.1101/2024.10.25.620247 — evolutionary biology — Posted on 2024-10-25
1124 OLIGONUCLEOTIDES TARGETING THE SPLICE ACCEPTOR SITE DOWNSTREAM OF A MICROEXON AS AN INNOVATIVE THERAPY FOR AUTISM
Martinez-Pizarro, A.; Pico, S.; Holm, L. L.; Doktor, T. K.; Andresen, B. S.; Lucas, J. J.; Desviat, L. R.
10.1101/2024.10.25.620162 — neuroscience — Posted on 2024-10-25
1125 Fitness compatibility and dengue virus inhibition in a Bangladeshi strain of Aedes aegypti infected with the Wolbachia strain wAlbB
Al-Amin, H. M.; Gyawali, N.; Graham, M.; Alam, M. S.; Lenhart, A.; Xi, Z.; Rasic, G.; Beebe, N. W.; Hugo, L. E.; Devine, G. J.
10.1101/2024.10.24.620043 — zoology — Posted on 2024-10-25
1129 Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping
de Visser, M. C.; Meilink, W. R. M.; Theodoropoulos, A.; Fahrbach, M.; Wielstra, B.
10.1101/2024.10.25.620256 — molecular biology — Posted on 2024-10-25
1131 HT SpaceM: A High-Throughput and Reproducible Method for Small-Molecule Single-Cell Metabolomics
Delafiori, J.; Shahraz, M.; Eisenbarth, A.; Hilsenstein, V.; Drotleff, B.; Bailoni, A.; Wadie, B.; Ekelöf, M.; Mattausch, A.; Alexandrov, T.
10.1101/2024.10.24.620114 — molecular biology — Posted on 2024-10-25
1132 Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF)
Gibb, A. A.; LaPenna, K. B.; Gaspar, R. B.; Latchman, N. R.; Tan, Y. F.; Choya-Foces, C.; Doiron, J. E.; Li, Z.; Xia, H.; Lazaropoulos, M. P.; Conwell, M.; Sharp, T. E.; Goodchild, T. T.; Lefer, D. J.; Elrod, J. W.
10.1101/2024.10.25.619450 — molecular biology — Posted on 2024-10-25
1133 Barley miRNAs and their targets regulation in response to heat stress at the early stage of development
Kruszka, K.; Pacak, A.; Swida-Barteczka, A.; Kesy, J.; Jarmolowski, A.; Szweykowska-Kulinska, Z.
10.1101/2024.10.25.620191 — molecular biology — Posted on 2024-10-25
1137 Composition of saliva metabolome is significantly associated with SARS-CoV2 infection and with severity of COVID-19 disease
Larios-Serrato, V.; Vazquez-Manjarrez, N.; Resendis-Antonio, O.; Rios-Sarabia, N.; Meza-Marquez, B.; Fiehn, O.; Torres, J.
10.1101/2024.10.24.620087 — bioinformatics — Posted on 2024-10-25
1140 Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape
Muir, D. F.; Asper, G. P. R.; Notin, P.; Posner, J. A.; Marks, D. S.; Keiser, M. J.; Pinney, M. M.
10.1101/2024.10.23.619915 — biochemistry — Posted on 2024-10-25
1143 Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes
Grau, B.; Kormos, R.; Bano-Polo, M.; Chen, K.; Garcia-Murria, M. J.; Hajredini, F.; Sanchez del Pino, M.; Jo, H.; Martinez-Gil, L.; Von Heijne, G.; DeGrado, W.; Mingarro, I.
10.1101/2024.10.23.619793 — molecular biology — Posted on 2024-10-25
1144 Probing DNA damage sites reveals context-dependent and novel DNA damage response factors
Cardoso da Silva, R.; Recchia, D. C.; Portegijs, V.; Trueba Sanchez, M. C.; Stecker, K. E.; van den Heuvel, S.; Baubec, T.
10.1101/2024.10.23.619792 — molecular biology — Posted on 2024-10-25
1146 Long-term Immunity of a Microneedle Array Patch of SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice
Kim, E.; Khan, M. S.; Shin, J.; Huang, S.; Ferrari, A.; Han, D.; An, E.; Kenniston, T. W.; Cassaniti, I.; Baldanti, F.; Jeong, D.; Gambotto, A.
10.1101/2024.10.25.620289 — microbiology — Posted on 2024-10-25
1147 Prevalence of Key Spike Protein Mutations and Their Limited Effect on COVID-19 Clinical Manifestations in Sylhet, Bangladesh
Akter, S.; Zeba, Z.; Hossain, M. A.; Ofori, M. A.; Shahab, M.; Rolim Silva, G. V.; Oliveira, J. I. N.; Akash, S.; Banu, T. A.; Islam, M.; Sarkar, M. H.; Goswami, B.; Chowdhury, S. F.; Habib, M. A.; Khan, M. S.
10.1101/2024.10.25.620187 — microbiology — Posted on 2024-10-25
1150 Understanding the epidemiology and pathogenesis of Mycobacterium tuberculosis with non-redundant pangenome and population genetics
Zhou, Y.; Anthony, R.; Wang, S.; Xia, H.; Ou, X.; Zhao, B.; Song, Y.; Zheng, Y.; He, P.; Liu, D.; Zhao, Y.; van Soolingen, D.
10.1101/2024.10.25.620184 — microbiology — Posted on 2024-10-25
1156 Too dim, too bright, and just right: Systems analysis of the Chlamydomonas diurnal program upon acclimation to light stress and limitation
Dupuis, S.; Ojeda, V.; Gallaher, S. D.; Purvine, S. O.; Glaesener, A. G.; Ponce, R.; Nicora, C. D.; Bloodsworth, K.; Lipton, M. S.; Niyogi, K. K.; Iwai, M.; Merchant, S. S.
10.1101/2024.10.22.618525 — systems biology — Posted on 2024-10-25
1161 Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma
Arguello, R. J.; Pierre, P.; Gigan, J. P.; Garcia-Gonzalez, P.; Galliot, L.; Ghaffar, Y.; Flores-Santibanez, F.; Seillier, E.; Lavignolle-Heguy, R.; Fischaux, S.; Dos Santos, D.; Combes, A.; Narita, M.; Gatti, E.; Nal, B.; Rocchi, S.; Moreaux, J.
10.1101/2024.10.22.617161 — cancer biology — Posted on 2024-10-25
1162 A high throughput single molecule platform to study DNA supercoiling effect on protein-DNA interactions
Lee, H.; Hwang, J.; Rashid, F.; London, J. A.; Fishel, R.; Berger, J. M.; Myong, S.; Ha, T.
10.1101/2024.10.24.620099 — biophysics — Posted on 2024-10-25
1163 SMART DATA FACTORY: VOLUNTEER COMPUTING PLATFORM FOR ACTIVE LEARNING-DRIVEN MOLECULAR DATA ACQUISITION
Ghukasyan, T.; Altunyan, V.; Bughdaryan, A.; Aghajanyan, T.; Smbatyan, K.; Papoian, G. A.; Petrosyan, G.
10.1101/2024.10.22.619651 — biophysics — Posted on 2024-10-25
1165 Organic opto-nanobiointerface enables multiscale biomodulation
Mueller, C.; Zhang, Y.; Meng, L.; Kalatanova, A.; Madsen, J. G.; Klompmaker, K. K.; Jakobsen, T. S.; Joergensen, A. C.; Askou, A. L.; Huang, G.; Li, W.; Davidsen, R. S.; Bek, T.; Hatzakis, N. S.; Corydon, T. J.; Leinonen, H. O.; Tian, B.; Dong, M.; Chen, M.
10.1101/2024.10.23.619813 — bioengineering — Posted on 2024-10-25
1169 Impact of land-use intensity, productivity, and aboveground richness on seed rain in temperate grasslands
Klinger, Y. P.; Kunze, S.; Hoelzel, N.; Freitag, M.; Klaus, V. H.; Kleinebecker, T.; Prati, D.; Neuenkamp, L.
10.1101/2024.10.22.619565 — ecology — Posted on 2024-10-25
1172 Mechanoreceptors initiate innate immunity in response to microbial infections
Stucchi, G.; Marongiu, L.; Rocca, G.; Galli, M.; Celant, A.; Cozzi, S.; Polissi, A.; Martorana, A. M.; Vai, M.; Orlandi, I.; Innocenti, M.; Granucci, F.
10.1101/2024.10.22.619631 — immunology — Posted on 2024-10-25
1173 Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
Edwards, M. M.; Nguyen, H. K.; Dodson, A. D.; Herbertson, A. J.; Honeycutt, M. K.; Slattery, J. D.; Rambousek, J. R.; Tsui, E.; Wolden-Hanson, T.; Wietecha, T. A.; Graham, J. L.; Tapia, G. P.; Sikkema, C. L.; O'Brien, K. D.; Mundinger, T. O.; Peskind, E. R.; Ryu, V.; Havel, P. J.; Khan, A. M.; Tabosky, G. J.; Blevins, J. E.
10.1101/2024.09.12.612710 — neuroscience — Posted on 2024-10-25
1176 Biocontrol efficiency and mechanism of novel Streptomyces luomodiensis SCA4-21 against banana Fusarium wilt
Qi, D.; Liu, Q.; Zou, L.; Chen, Y.; Feng, J.; Zhang, M.; Li, K.; Zhao, Y.; Zhou, D.; Wang, W.; Xie, J.
10.1101/2024.10.22.619680 — physiology — Posted on 2024-10-25
1177 Cannabidiol Toxicity Driven by Hydroxyquinone Formation
Montero, M. I.; Rajaram, P. S.; Alvarado, J. E. Z.; McCloskey, K. E.; Baxter, R. D.; Eguiluz, R. C. A.
10.1101/2024.10.22.619647 — pharmacology and toxicology — Posted on 2024-10-25
1178 Loss of long-chain acyl-CoA dehydrogenase protects against acute kidney injury
Chiba, T.; Oda, A.; Zhang, Y.; Bons, J.; Bharathi, S.; Pfister, K. E.; Zhang, B. B.; Richert, A. C.; Schilling, B.; Goetzman, E. S.; Sims-Lucas, S.
10.1101/2024.10.22.619640 — pathology — Posted on 2024-10-25
1179 Anemia and tissue hypoxia are major determinants of malarial hypelactatemia
Georgiadou, A.; Yoon, C. E.; Yu, H.; Pearson, W. H.; Ueno, A.; Ebmeier, S.; Larrouy-Maumus, G.; Cunnington, A. J.
10.1101/2024.10.22.619641 — pathology — Posted on 2024-10-25
1180 Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer
Miao, W.; Jain, V.; Han, M.; Jin, Y. J.; Beasley, G. M.; Starczynowski, D. T.; Gregory, S. G.; Zhang, J. Y.
10.1101/2024.10.22.619436 — cancer biology — Posted on 2024-10-25
1181 Extrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastoma
Noorani, I.; Haughey, M.; Luebeck, J.; Rowan, A.; Grönroos, E.; Terenzi, F.; Wong, I. T.-L.; Kittel, J.; Bailey, C.; Weeden, C.; Bell, D.; Joo, E.; Barbe, V.; Jones, M. G.; Nye, E.; Green, M.; Meader, L.; Norton, E. J.; Fabian, M.; Kanu, N.; Jamal-Hanjani, M.; Santarius, T.; Nicoll, J.; Boche, D.; Chang, H. Y.; Bafna, V.; Huang, W.; Mischel, P. S.; Swanton, C.; Werner, B.
10.1101/2024.10.22.619657 — cancer biology — Posted on 2024-10-25
1182 Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity
Kwon, J.; Dilly, J.; Liu, S.; Kim, E.; Bian, Y.; Dharmaiah, S.; Tran, T. H.; Kapner, K. S.; Ly, S. H.; Yang, X.; Rabara, D.; Waybright, T. J.; Giacomelli, A. O.; Hong, A. L.; Misek, S. L.; Wang, B.; Ravi, A.; Beroukhim, R.; Lemke, C. T.; Haigis, K. M.; Esposito, D.; Root, D. E.; Nissley, D. V.; Stephen, A. G.; McCormick, F.; Simanshu, D. K.; Hahn, W. C.; Aguirre, A. J.
10.1101/2024.10.22.618529 — cancer biology — Posted on 2024-10-25
1183 IRE1-dependent GOLIM4 expression controls protein secretion to modulate glioblastoma cell adhesion and migration
Bakambamba, K.; Nivet, M.; Sauzay, C.; Martin, S.; Lafont, E.; Negroni, L.; Chevet, E.; Avril, T.
10.1101/2024.10.22.619629 — cancer biology — Posted on 2024-10-25
1184 The Single-Stranded DNA-Binding Factor SUB1/PC4 Alleviates Replication Stress at Telomeres and is a Vulnerability of ALT Cancer Cells
Dubois, J.-C.; Bonnell, E.; Frion, J.; Zimmer, S.; Khan, M. R.; Teplitz, G. M.; Casimir, L.; Methot, E.; Filion, A.; Idrissou, M.; Jacques, P.-E.; Wellinger, R. J.; Marechal, A.
10.1101/2024.10.22.619621 — cancer biology — Posted on 2024-10-25
1188 K-mer analysis of long-read alignment pileups for structural variant genotyping
ENGLISH, A. C.; Cunial, F.; Metcalf, G. A.; Gibbs, R. A.; Sedlazeck, F. J.
10.1101/2024.10.22.619642 — bioinformatics — Posted on 2024-10-25
1192 H2-driven xylitol production in Cupriavidus necator H16
Jämsä, T.; Claassens, N. J.; Salusjärvi, L.; Nyyssölä, A.
10.1101/2024.10.22.619622 — bioengineering — Posted on 2024-10-25
1194 The genome assembly of the duckweed fern, Azolla caroliniana
Song, M. J.; Li, F.-W.; Freund, F.; Escalona, M.; Toffelmier, E.; Miller, C.; Shaffer, H. B.; Nguyen, O.; Marimuthu, M. P. A.; Chumchim, N.; Tribble, C.; Fairbairn, C. W.; Seligmann, W.; Rothfels, C. J.
10.1101/2024.10.22.619683 — genomics — Posted on 2024-10-25
1195 Changes in the cellular composition of the endometrium during the implantation window are associated with recurrent pregnancy loss
Reddin, I. G.; Pearson-Farr, J. E.; Turaj, A. H.; Lim, S. H.; Lewis, R. M.; Cheong, Y. C.; Cleal, J. K.
10.1101/2024.10.22.619501 — genomics — Posted on 2024-10-25
1197 Development and validation of versatile species-specific primer assays for eDNA monitoring and authentication of 10 commercially important Peruvian marine species
Marin, A.; Alfaro, R.; Reyes-Flores, L.; Ingar, C.; Santos-Rojas, L.; Alvarez-Jaque, I.; Rodriguez-Bernales, K.; Carbajal, C.; Yon-Utrilla, A.; Zelada-Mazmela, E.
10.1101/2024.10.22.619663 — genetics — Posted on 2024-10-25
1198 Cooperation maximizes biodiversity
Godoy, O.; Soler-Toscano, F.; Portillo, J. R.; Suarez, A.; Langa, J. A.
10.1101/2024.10.22.619656 — ecology — Posted on 2024-10-25
1199 Degradation of fish food webs in the anthropocene
Carvajal-Quintero, J. D.; Dornelas, M.; Comte, L.; Herrera-Perez, J.; Tedesco, P. A.; Giam, X.; Brose, U.; Chase, J.
10.1101/2024.10.22.619402 — ecology — Posted on 2024-10-25
1200 In silico nanoscope to study the interplay of genome organization and transcription regulation
Gopi, S.; Brandani, G. B.; Tan, C.; Jung, J.; Gu, C.; Mizutani, A.; Ochiai, H.; Sugita, Y.; Takada, S.
10.1101/2024.10.22.619557 — molecular biology — Posted on 2024-10-25
1201 Activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease with antiviral efficacy in murine infection model
Choudhary, S.; Nehul, S.; Nagaraj, S. K.; Narayan, R.; Verma, S.; Sharma, S.; Kumari, A.; Rani, R.; Saha, A.; Sircar, D.; Kaliappan, A.; Tripathi, S.; Sharma, G. K.; Kumar, P.; Tomar, S.
10.1101/2022.11.11.516107 — microbiology — Posted on 2024-10-25
1203 Understanding disease-associated metabolic changes in human colon epithelial cells using iColonEpithelium metabolic reconstruction
Jiang, B.; Quinn-Bohmann, N.; Diener, C.; Nathan, V. B.; Han-Hallett, Y.; Reddivari, L.; Gibbons, S. M.; Baloni, P.
10.1101/2024.10.22.619644 — systems biology — Posted on 2024-10-25
1204 The mitochondrial-targeted antioxidant SkQ1 prevents mitochondrial-linked apoptosis but not necroptosis or skeletal muscle atrophy in ovarian cancer
Khajehzadehshoushtar, S.; Delfinis, L. J.; Rahman, F. A.; Garibotti, M. C.; Gandhi, S.; Brahmbhatt, A. N.; Morris, B. A.; Garlisi, B.; Lauks, S.; Aitken, C.; Zhang, Z.-X.; Simpson, J. A.; Quadrilatero, J.; Petrik, J.; Perry, C. G. R.
10.1101/2024.10.22.617245 — physiology — Posted on 2024-10-25
1205 Transcriptional profiling provides insights on sublethal thermal stress thresholds in juvenile bull trout
Best, C.; Durhack, T. C.; Chapelsky, A. J.; Aminot, M.; Islam, S. S.; Heath, D. D.; Mochnacz, N. J.; Jeffries, K. M.
10.1101/2024.10.22.619659 — physiology — Posted on 2024-10-25
1206 Dose- and time-dependent effects of cobalt protoporphyrin IX on granulocyte mobilization and metabolic markers in mice
Bednarz, A.; Kozuch, P.; Kowalski, K.; Skulimowska, I.; Kachamakova-Trojanowska, N.; Filipek-Gorzala, J.; Kwiecinska, P.; Gawlinska, K.; Kubiak, A.; Bryniarska-Kubiak, N.; Jozkowicz, A.; Szade, K.; Szade, A.
10.1101/2024.10.22.619673 — pharmacology and toxicology — Posted on 2024-10-25
1207 Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells
Sakwe, N. I.; Vuong, N. B.; Black, P. J.; Ball, D. D.; Thomas, P.; Beasley, H. K.; Hinton, A.; Ochieng, J.; Sakwe, A. M.
10.1101/2024.10.22.619710 — cancer biology — Posted on 2024-10-25
1210 Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin
Lemmex, A.; Allred, J.; Ostergard, J.; Trask, J.; Bui, H. N.; Anderson, M.; Kopp, B.; Streeter, O.; Smiley, A.; Babilonia-Diaz, N. S.; Blazar, B. R.; Higgins, L.; Gordon, P. M.; Muretta, J. M.; Gordon, W. R.
10.1101/2024.10.22.617501 — biochemistry — Posted on 2024-10-25
1211 AMPK activation promotes transcriptional activation of TFEB through its dephosphorylation
Negoita, F.; Bringas, C. F.; Hellberg, K.; Luda, K. M.; Liu, H.; Cuenco, J.; Zhao, J.-F.; Sathe, G.; Sapkota, G.; Sakamoto, K.
10.1101/2024.10.22.619589 — biochemistry — Posted on 2024-10-25
1215 Antibody Profiles Elicited by Potent and Subpotent Whole Cell Pertussis Vaccines in Mice
Adewunmi, Y.; Doering, J.; Kumar, P.; Pablo, J. V.; Teng, A. A.; Huynh, V.; Secrist, K.; Volkin, D.; Joshi, S.; Campo, J. J.; MANTIS, N. J.
10.1101/2024.10.22.619719 — immunology — Posted on 2024-10-25
1216 Identification of immunogenic and cross-reactive chikungunya virus-specific CD4+ T cell epitopes in chronic chikungunya viral arthritic disease in humans
Agarwal, R.; Ha, C.; Cortes, F. H.; Lee, Y.; Martinez-Perez, A.; Galvez, R.; Castillo, I.; Balmaseda, A.; Harris, E.; Romero-Vivas, C. M.; Lakshmanane, P.; Falconar, A. K.; Grifoni, A.; Sette, A.; Weiskopf, D.
10.1101/2024.10.22.619717 — immunology — Posted on 2024-10-25
1217 Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection
Ottinger, S.; Larson, A. B.; Mercado-Evans, V.; Branthoover, H.; Zulk, J. J.; Serchejian, C.; Mejia, M. E.; Hameed, Z. A.; Walde, R.; Fleck, R. C.; Shea, A. E.; Patras, K. A.
10.1101/2024.10.22.619711 — immunology — Posted on 2024-10-25
1219 Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice
Delfinis, L. J.; Khajehzadehshoushtar, S.; Flewwelling, L. J.; Andrews, N. J.; Garibotti, M. C.; Gandhi, S.; Brahmbhatt, A. N.; Morris, B. A.; Garlisi, B.; Lauks, S.; Aitken, C.; Tsitkanou, S.; Simpson, J. A.; Greene, N. P.; Cheng, A. J.; Petrik, J.; Perry, C. G. R.
10.1101/2024.10.22.619751 — physiology — Posted on 2024-10-25
1220 An attractor state zone precedes neural crest fate in melanoma initiation
McConnell, A. M.; Chasse, M. H.; Noonan, H. R.; Mito, J. K.; Barbano, J.; Weiskopf, E.; Gosselink, I. F.; Prasad, M.; Yang, S.; Abarzua, P.; Lian, C. G.; Murphy, G. F.; Trapnell, C.; Zon, L. I.
10.1101/2024.10.22.618007 — cancer biology — Posted on 2024-10-25
1225 When to Trust Epigenetic Clocks: Avoiding False Positives in Aging Interventions.
Borrus, D. S.; Sehgal, R.; Armstrong, J. F.; Kasamoto, J.; Gonzalez, J.; Higgins-Chen, A. T.
10.1101/2024.10.22.619720 — genomics — Posted on 2024-10-25
1227 Learning antibody sequence constraints from allelic inclusion
Jagota, M.; Hsu, C.; Mazumder, T.; Sung, K.; DeWitt, W. S.; Listgarten, J.; Matsen, F. A.; Ye, C. J.; Song, Y. S.
10.1101/2024.10.22.619760 — immunology — Posted on 2024-10-25
1230 Divergent biosynthesis of monoterpene indole alkaloids from geissoschizine
Kamileen, M. O.; Hong, B.; Gase, K.; Kunert, M.; Caputi, L.; Lichman, B. R.; O'Connor, S. E.
10.1101/2024.10.22.619577 — biochemistry — Posted on 2024-10-25
1233 TIR signaling activates caspase-like immunity in bacteria
ROUSSET, F.; Osterman, I.; Scherf, T.; Falkovich, A.; Leavitt, A.; Amitai, G.; Shir, S.; Malitsky, S.; Itkin, M.; Savidor, A.; Sorek, R.
10.1101/2024.10.24.620036 — microbiology — Posted on 2024-10-25
1234 Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy
Gandhi, S.; Delfinis, L. J.; Bhatt, P.; Garibotti, M. C.; Bellissimo, C. A.; Goli, A. N.; Morris, B. A.; Brahmbhatt, A. N.; Yakobov-Shimonov, S.; Rahman, F. A.; Quadrilatero, J.; Simpson, J. A.; Sweeney, G.; Abdul-Sater, A. A.; Backx, P. H.; Hsu, H. H.; Perry, C. G.
10.1101/2024.10.23.619868 — physiology — Posted on 2024-10-25
1235 Chromosomal instability promotes cell migration and invasion via EFEMP1 in extracellular vesicles
Foijer, F.; Zheng, S.; Tian, R.; Liu, Y.; Wardenaar, R.; Shirzai, M.; Kempe, L.; Dijkstra, E.; Warzawik, E.; Suarez Peredo Rodriguez, M. F.; Sjollema, K.; Bakker, P.; Rijn, P. v.; Borghesan, M.; Paridaen, J. T.; Santaguida, S.
10.1101/2024.10.21.619397 — cancer biology — Posted on 2024-10-25
1236 Angiogenic and Immune Predictors of Neoadjuvant Axitinib Response in Renal Cell Carcinoma with Venous Tumour Thrombus
Wray, R.; Paverd, H.; Machado, I.; Barbieri, J.; Easita, F.; Edwards, A. R.; Gallagher, F. A.; Mendichovszky, I. A.; Mitchell, T. J.; de la Roche, M.; Shields, J. D.; Ursprung, S.; Wallis, L.; Warren, A. Y.; Welsh, S. J.; Crispin-Ortuzar, M.; Stewart, G. D.; Jones, J. O.; NAXIVA study group,
10.1101/2024.10.22.619358 — cancer biology — Posted on 2024-10-25
1238 Assembling Ruthenium Complexes to Form Ruthenosome Unleashing Ferritinophagy-mediated Tumor Suppression
Meng, C.; Li, S.; Ma, Y.; Yu, H.; Song, J.; Zhi, J.; Zhu, B.; Shao, L.; Liu, X.; Yang, L.; Zhang, M.; Zhang, Y.; Li, G.
10.1101/2024.10.22.619580 — biochemistry — Posted on 2024-10-25
1239 Iridescent structural coloration in a crested Cretaceous enantiornithine bird from Jehol Biota
LI, Z.; Hu, J.; Stidham, T.; Ye, M.; Wang, M.; Pan, Y.; Zhao, T.; Li, J.; Zhou, Z.; Clarke, J.
10.1101/2024.10.21.619362 — evolutionary biology — Posted on 2024-10-25
1240 An unexplored diversity for adaptation of germination to high temperatures in Brassica species
Tiret, M.; Wagner, M.-H.; Gay, L.; Chenel, E.; Dupont, A.; Falentin, C.; Gavory, F.; Labadie, K.; Ducournau, S.; Chevre, A.-M.
10.1101/2024.10.22.619588 — evolutionary biology — Posted on 2024-10-25
1241 Unc-51-like Kinase 1 (ULK1) Regulates Bacterial Ubiquitylation and p62 Recruitment during Xenophagic Clearance of Listeria monocytogenes
Siqueira, M. S.; de farias, T. S. d. M.; Ribeiro, J. S.; Ribeiro, R. d. M.; Pereira, T. D.; Carneiro, L. A. M.; Travassos, L. H.
10.1101/2024.10.23.619899 — cell biology — Posted on 2024-10-25
1250 Comparison of immunogenicity and protection efficacy of self-amplifying and circular mRNA vaccines for SARS-CoV-2
Singh, O. N.; Berry, U.; Joshi, G.; Asuru, T. R.; Chandrasekar, K.; Narayanan, S.; Srivastava, P.; Tiwari, M.; Chattopadhyay, S.; Mehdi, F.; Panda, B. N.; Nayak, D.; Mani, S.; Shrivastava, T.; Batra, G.; Ranjith-Kumar, C.; Guchhait, P.; Surjit, M.
10.1101/2024.08.23.609366 — microbiology — Posted on 2024-10-25
1251 Reduction in ETFDH expression optimizes cancer cell bioenergetics
Papadopoli, D.; Palia, R.; Jovanovic, P.; Tabaries, S.; Ciccolini, E.; Sabourin, V.; Igelmann, S.; McLaughlan, S.; Zhan, L.; Kim, H.; Chekkal, N.; Szkop, K. J.; Bertomeu, T.; Zeng, J.; Vassalakis, J.; Afzali, F.; Mzoughi, S.; Guccione, E.; Tyers, M.; Avizonis, D.; Larsson, O.; Postovit, L.-M.; Djuranovic, S.; Ursini-Siegel, J.; Siegel, P. M.; Pollak, M.; Topisirovic, I.
10.1101/2024.10.25.620155 — cancer biology — Posted on 2024-10-25
1252 AI-readiness for Biomedical Data: Bridge2AI Recommendations
Clark, T.; Caufield, H.; Mohan, J. A.; Al Manir, S.; Amorim, E.; Eddy, J.; Gim, N.; Gow, B.; Goar, W.; Haendel, M.; Hansen, J. N.; Harris, N.; Hermjakob, H.; McWeeney, S. K.; Nebeker, C.; Nikolov, M.; Shaffer, J.; Sheffield, N.; Sheynkman, G.; Stevenson, J.; Mungall, C.; Chen, J. Y.; Wagner, A.; Kong, S. W.; Ghosh, S. S.; Patel, B.; Williams, A.; Munoz-Torres, M. C.
10.1101/2024.10.23.619844 — bioinformatics — Posted on 2024-10-25
1253 Oncogenic Alterations, Race, and Survival in US Veterans with Metastatic Prostate Cancer Undergoing Somatic Tumor Next Generation Sequencing
Valle, L. F.; Li, J.; Desai, H.; Hausler, R.; Haroldsen, C.; Chatwal, M. S.; Ojo, M.; Kelley, M. J.; Rebbeck, T.; Rose, B. S.; Rettig, M. B.; Nickols, N. G.; Garraway, I. P.; Yamoah, K.; Maxwell, K. N.
10.1101/2024.10.24.620071 — genomics — Posted on 2024-10-25
1254 Integrating predictors of host condition into spatiotemporal multi-scale models of virus shedding
Kramer, A. M.; Faust, C. L.; Castellanos, A. A.; Fischhoff, I. R.; Peel, A. J.; Eby, P.; Ruiz-Aravena, M.; Borremans, B.; Plowright, R. K.; Han, B. A.
10.1101/2024.10.24.616488 — ecology — Posted on 2024-10-25
1255 Proteomic associations with cognitive variability as measured by the Wisconsin Card Sorting Test in a healthy Thai population: A machine learning approach
Chen, C.; Khanthiyong, B.; Thaweetee-Sukjai, B.; Charoenlappanit, S.; Roytrakul, S.; Surit, P.; Phoungpetchara, I.; Thanoi, S.; Reynolds, G. P.; Nudmamud-Thanoi, S.
10.1101/2024.10.25.620177 — neuroscience — Posted on 2024-10-25
1259 A framework for target discovery in rare cancers
Li, B.; Sadagopan, A.; Li, J.; Wu, Y.; Cui, Y.; Weiss, C.; Konda, P.; Choueiri, T.; Doench, J.; Viswanathan, S.
10.1101/2024.10.24.620074 — cancer biology — Posted on 2024-10-25
1262 Getting Started with Machine Learning for Experimental Biochemists and Other Molecular Scientists
Vince, M. J.; Hughes, K. A.; Buzuk, A.; Perlstein, D. L.; Viarengo-Baker, L. A.; Whitty, A.
10.1101/2024.10.23.619819 — biochemistry — Posted on 2024-10-25
1263 Epigenetic control of Topoisomerase 1 activity presents a cancer vulnerability
Lee, T.; Qiao, C. X.; Kuzin, V.; Shi, Y.; Ramanaranayan, V.; Wu, T.; Zhou, X.; Corujo, D.; Buschbeck, M.; Baranello, L.; Oberdoerffer, P.
10.1101/2024.10.22.619113 — molecular biology — Posted on 2024-10-25
1264 Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies
Maurer, D. P.; Vu, M.; Ramos, A. S. F.; Dugan, H. L.; Khalife, P.; Geoghegan, J. C.; Walker, L. M.; Bajic, G.; Schmidt, A. G.
10.1101/2024.10.22.619298 — immunology — Posted on 2024-10-25
1265 Two species and two karyotypes? Cytogenetic differentiation between Passiflora foetida L. and P. vesicaria L. (Passifloraceae)
Zirpoli, B.; Monteiro da Silva, A. R.; Rodriguez, P. E.; Leal Viana, B.; Rodrigues Marciel, J.; Pedrosa-Harand, A.; Sader, M. A.
10.1101/2024.10.23.619917 — plant biology — Posted on 2024-10-25
1266 Root Remodeling Mechanisms and Salt Tolerance Trade-Offs: The Roles of HKT1, TMAC2, and TIP2;2 in Arabidopsis
Alshareef, N.; Melino, V.; Saber, N.; De Rosa, A.; Rey, E.; Wang, J. Y.; AlBabili, S.; Byrt, C.; Tester, M.; Julkowska, M. M.
10.1101/2024.10.23.619678 — plant biology — Posted on 2024-10-25
1268 EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes
Patel, N. P.; Shen, A.; Wada, Y.; Blair, M. A.; Mitchell, D. W.; Vanags, L. R.; Woo, S.; Ku, M. J.; Dauda, K. S.; Morris, W. A.; Yang, M.; Knollmann, B. C.; Roden, D. M.; Salem, J. E.; Glazer, A. M.; Kroncke, B. M.
10.1101/2024.10.21.619481 — pharmacology and toxicology — Posted on 2024-10-25
1269 Automated segmentation of synchrotron-scanned fossils
During, M. A. D.; Matelsky, J. K.; Gustafsson, F. K.; Voeten, D. F. A. E.; Chen, D.; Wester, B. A.; Kording, K. P.; Ahlberg, P. E.; Schön, T. B.
10.1101/2024.10.23.619778 — paleontology — Posted on 2024-10-25
1271 CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
Sun, Y.; Kronenberg, N. M.; Sethi, S. K.; Dash, S. N.; Kovalik, M. E.; Sempowski, B.; Strickland, S.; Raina, R.; Sperati, C. J.; Tian, X.; Ishibe, S.; Hall, G.; Gather, M. C.
10.1101/2024.10.22.619513 — biophysics — Posted on 2024-10-25
1273 The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 Box B
DeBono, N. J.; D'Andrea, S.; Bandala-Sanchez, E.; Goddard-Borger, E. D.; Zenaidee, M.; Moh, E. S. X.; Fadda, E.; Harrison, L. C.; Packer, N. H.
10.1101/2024.10.24.620132 — molecular biology — Posted on 2024-10-25
1274 The Nuclear Pore Complex acts as a hub for pri-miRNA transcription and processing in plants
Gonzalo, L.; Gagliardi, D.; Zlauvinen, C.; Gulanicz, T.; Arce, A. L.; Fernandez, J.; Cambiagno, D. A.; Zienkiewicz, A.; Jarmolowski, A.; Manavella, P. A.
10.1101/2024.10.24.620027 — plant biology — Posted on 2024-10-25
1275 Quantitative light element (sodium and potassium) profiling in plant tissues using monochromatic X-ray fluorescence analysis
Kahlon, P. S.; Kokkinopoulou, P.; Alfageme, S. B.; Leong, C. K.; Chen, Z.; Testerink, C.; van der Ent, A.
10.1101/2024.10.22.619597 — plant biology — Posted on 2024-10-25
1276 A unified framework for hydromechanical signaling: Do plant signals go with the flow?
Bacheva, V.; Rockwell, F.; Salmon, J.-B.; Woodson, J. D.; Frank, M.; Stroock, A.
10.1101/2024.10.23.619842 — plant biology — Posted on 2024-10-25
1278 Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense
Han, W.-H.; Zhang, F.-B.; Ji, S.-X.; Liang, K.-L.; Wang, J.-X.; Fan, X.-P.; Liu, S.-S.; Wang, X.-W.
10.1101/2024.10.23.619823 — plant biology — Posted on 2024-10-25
1279 Biocultural vulnerability of traditional crops in the Indian Trans Himalaya
Jaggi, H.; Anand, A.; Solari, K. A.; Echeverri, A.; Tobge, R.; Tsewang, T.; Suryawanshi, K.; Tuljapurkar, S. D.
10.1101/2024.10.22.619747 — plant biology — Posted on 2024-10-25
1280 The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity
Simonsen, B.; Ruebsam, H.; Kolte, M. V.; Larsen, M. M.; Kroenauer, C.; Gysel, K.; Laursen, M.; Feng, F.; Kaya, G.; Oldroyd, G.; Stougaard, J.; Fort, S.; Radutoiu, S.; Andersen, K. R.
10.1101/2024.10.23.619817 — plant biology — Posted on 2024-10-25
1281 CRISPR knockout of winter-biased SUT4 alters phenology, biomass accrual, and fertility of field-grown hybrid poplar
Tuma, T. T.; McInnes, H. A.; Pham, H.; Bewg, W. P.; Deguchi, M.; Zhou, R.; Surber, S. M.; Lipzen, A.; Barry, K. W.; Lieb, B.; Weber Wyneken, D. L.; Harman-Ware, A. E.; Dahlen, J.; Harding, S.; Tsai, C.-J.
10.1101/2024.10.22.619524 — plant biology — Posted on 2024-10-25
1282 Harnessing AlphaFold to reveal hERG channel conformational state secrets
Ngo, K.; Yang, P.-C.; Yarov-Yarovoy, V.; Clancy, C. E.; Vorobyov, I.
10.1101/2024.01.27.577468 — biophysics — Posted on 2024-10-25
1285 A general model for the seasonal to decadal dynamics of leaf area
Zhou, B.; Cai, W.; Zhu, Z.; Wang, H.; Harrison, S.; Prentice, C.
10.1101/2024.10.23.619947 — plant biology — Posted on 2024-10-25
1288 B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
Cho, S. H.; Jones, M. A.; Meyer, K.; Anderson, D. M.; Chetyrkin, S.; Calcutt, M. W.; Caprioli, R. M.; Semenkovich, C. F.; Boothby, M. R.
10.1101/2024.10.17.618760 — immunology — Posted on 2024-10-24
1290 Dendritome Mapping Unveils Spatial Organization of Striatal D1/D2-Neuron Morphology
Park, C. S.; Yan, M.; Zhu, M.; Akram, M. A.; Foster, N. N.; Bennecke, A.; Choi, C.; Marrett, K.; Moradi, K.; Zhang, J. Y.; Magat, G.; Nanda, S.; Vaca, R.; Wijaya, K.; Zablan, J. R.; Lee, S.; Song, C.; Lara, M. J.; Louie, M.; Cong, J.; Kim, Y.; Ascoli, G. A.; Langfelder, P.; Tward, D.; Dong, H.-W.; Yang, X. W.
10.1101/2024.10.24.619934 — neuroscience — Posted on 2024-10-24
1291 Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group
Cimmino, D.; Zabriskie, B.; Luke, S.; Gutman, B.; Isaev, D.; Glahan, D.; Pearlson, G.; Rodigue, A.; Calhoun, V.; Ehrlich, S.; Andreassen, O.; Tordesillas-Gutierrez, D.; Crespo-Facorro, B.; Satterthwaite, T.; Gur, R.; Gur, R.; Spalletta, G.; Piras, F.; Donohoe, G.; McDonald, C.; Pomarol-Clotet, E.; Salvador, R.; Karuk, A.; Voineskos, A.; Kochunov, P.; Borgwardt, S.; Agartz, I.; Jonsson, E.; Kircher, T.; Stein, F.; Brosch, K.; Nenadic, I.; Iasevoli, F.; Pontillo, G.; de Bartolomeis, A.; Barone, A.; Ciccarelli, M.; Di Giorgio, A.; Brunetti, A.; Cocozza, S.; Tranfa, M.; James, A.; Zarei, M.; Hough
10.1101/2024.10.24.619733 — neuroscience — Posted on 2024-10-24
1294 Cortical norepinephrine-astrocyte signaling critically mediates learned behavior
Drummond, G. T.; Natesan, A.; Celotto, M.; Shih, J.; Ojha, P.; Osako, Y.; Park, J.; Sipe, G. O.; Jenks, K. R.; Breton-Provencher, V.; Simpson, P. C.; Panzeri, S.; Sur, M.
10.1101/2024.10.24.620009 — neuroscience — Posted on 2024-10-24
1297 Iron and redox sensing in plants: properties of the hemerythrin-like domains of Arabidopsis BRUTUS and BRUTUS-LIKE2 proteins
Pullin, J.; Rodriguez-Celma, J.; Franceschetti, M.; Mundy, J. E.; Svistunenko, D. A.; Bradley, J. M.; le Brun, N. E.; Balk, J.
10.1101/2024.10.23.619806 — biochemistry — Posted on 2024-10-24
1299 TFAM as a sensor of UVC-induced mitochondrial DNA damage
King, D. E.; Beard, E. E.; Satusky, M. J.; Ryde, I. T.; George, A.; Johnson, C.; Dolan, E. L.; Zhang, Y.; Zhu, W.; Wilkins, H.; Corden, E.; Murphy, S. K.; Erie, D.; Gordan, R.; Meyer, J. N.
10.1101/2024.10.24.620005 — biochemistry — Posted on 2024-10-24
1300 Revisiting the paradigm of anhematophagy in male mosquitoes
Bozic, J.; Joseph, R. E.; Krizek, R. S.; Holley, A.; Laroche, M.; Benoit, J. B.; Rasgon, J. L.
10.1101/2024.10.08.617226 — animal behavior and cognition — Posted on 2024-10-24
1301 Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics
Avelar-Rivas, J. A.; Sedeno, I.; Garcia-Ortega, L. F.; Urban Aragon, J. A.; Mancera, E.; DeLuna, A.; Morales, L.
10.1101/2024.09.27.615306 — evolutionary biology — Posted on 2024-10-24
1305 Trafficking of the Telomerase RNA using a Novel Genetic Approach
Kirk, K. E.; Day, J. K.; Palmero, B. J.; Allred, A. L.; Li, J.; Hooda, F. B.; Witte, G.; Dejneka, A. M.; Sandler, A. M.
10.1101/2024.10.22.619658 — molecular biology — Posted on 2024-10-24
1307 Dynamics of gut colonization by commensal and pathogenic bacteria that adhere to the intestinal epithelium
Rivera, D. E.; Poirier, K.; Moore, S.; Nicolle, O.; Morgan, E.; Longares, J. F.; Singh, A.; Michaux, G.; Felix, M.-A.; Luallen, R.
10.1101/2024.10.24.620080 — microbiology — Posted on 2024-10-24
1309 Aromatase-independent estrogenesis: Wood-Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere
Wang, P.-H.; Wu, T.-Y.; Chen, Y.-L.; Gicana, R. G.; Lee, T.-H.; Chen, M.-J.; Hsiao, T.-H.; Lu, M.-Y. J.; Lai, Y.-L.; Wang, T.-Y.; Li, J.-Y.; Chiang, Y.-R.
10.1101/2024.10.24.619986 — microbiology — Posted on 2024-10-24
1310 Emergence and disruption of cooperativity in a denitrifying microbial community
Carr, A. V.; Otwell, A. E.; Hunt, K. A.; Chen, Y.; Wilson, J.; Faria, J. P.; Liu, F.; Edirisinghe, J. N.; Valenzuela, J. J.; Turkarslan, S.; Lui, L. M.; Nielson, T.; Arkin, A. P.; Henry, C. S.; Petzold, C. J.; Stahl, D. A.; Baliga, N. S.
10.1101/2024.10.24.620115 — microbiology — Posted on 2024-10-24
1312 The microbiome shapes immunity in a sex-specific manner in mouse models of Alzheimer's disease
Bostick, J. W.; Connerly, T. J.; Thron, T.; Needham, B. D.; de Castro Fonseca, M.; Kaddurah-Daouk, R.; Knight, R.; Mazmanian, S. K.
10.1101/2024.05.07.593011 — microbiology — Posted on 2024-10-24
1313 Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malaria
Marques-da-Silva, C.; Schmidt-Silva, C.; Bowers, C.; Charles-Chess, E.; Shiau, J. C.; Park, E.-S.; Yuan, Z.; Kim, B.-H.; Kyle, D. E.; Harty, J. T.; MacMicking, J. D.; Kurup, S. P.
10.1101/2024.10.22.619707 — immunology — Posted on 2024-10-24
1315 Genetically-Encoded Fluorescence Barcodes for Single-Cell Analysis
Lu, X.; Pritko, D. J.; Abravanel, M. E.; Huggins, J. R.; Ogunleye, F.; Biswas, T.; Ashy, K. C.; Woods, S. K.; Livingston, M. W.; Blenner, M.; Birtwistle, M. R.
10.1101/2024.10.23.619855 — synthetic biology — Posted on 2024-10-24
1319 Efficient secretion of a plastic degrading enzyme from the green algae Chlamydomonas reinhardtii
Molino, J. V. D.; Saucedo, B.; Kang, K.; Walsh, C.; Diaz, C. J.; Tessman, M.; Mayfield, S. P.
10.1101/2024.10.23.619606 — bioengineering — Posted on 2024-10-24
1320 Optical control of sphingolipid biosynthesis using photoswitchable sphingosines
Kol, M.; Novak, A. J. E.; Morstein, J.; Schroer, C.; Sokoya, T.; Mensing, S.; Korneev, S. M.; Trauner, D.; Holthuis, J. C. M.
10.1101/2024.10.24.619506 — biochemistry — Posted on 2024-10-24
1321 Topological rearrangements activate the HerA-DUF anti-phage defense system
Rish, A. D.; Fosuah, E.; Shen, Z.; Marathe, I. A.; Wysocki, V. H.; Fu, T.
10.1101/2024.10.24.620088 — biochemistry — Posted on 2024-10-24
1324 Duplex PCR assay to determine sex and mating status of Ixodes scapularis (Acari: Ixodidae), vector of the Lyme disease pathogen
Ronai, I.; Frederick, J. C.; Thompson, A. T.; Sharma, P.; Yabsley, M. J.; Pal, U.; Extavour, C. G.; Glenn, T. C.
10.1101/2024.10.23.619921 — genomics — Posted on 2024-10-24
1325 The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies
Adams, D.; Quail, M.; Bonner, I.; Lilue, J.; Reinholdt, L.; Czechanski, A.; Francis, B.; Keane, T. M.; Helmy, M.; Kasahara, T.; Gozashti, L.; Harringmeyer, O. S.; Costello, K.; Smith, A. F.; Dawson, E.; Kato, T.
10.1101/2024.10.24.619615 — genomics — Posted on 2024-10-24
1326 SARS-CoV-2 within-host population expansion, diversification and adaptation in zoo tigers, lions and hyenas
Bashor, L.; Gallichotte, E. N.; Galvan, M.; Erbeck, K.; Croft, L.; Stache, K.; Stenglein, M. D.; Johnson, J. G.; Pabilonia, K.; VandeWoude, S.
10.1101/2024.10.24.620075 — evolutionary biology — Posted on 2024-10-24
1328 Virulence regulates and boosts CRISPR-Cas9 immunity in Group B Streptococcus
Pastuszka, A.; Mazzuoli, M.-V.; Crestani, C.; Deborde, L.; Sismeiro, O.; Lemaire, C.; Rong, V.; Gominet, M.; Jacquemet, E.; Legendre, R.; Lanotte, P.; Firon, A.
10.1101/2024.10.24.620037 — microbiology — Posted on 2024-10-24
1330 T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
Bozkus, C. C.; Brown, M.; Velazquez, L.; Thomas, M.; Wilson, E. A.; O'Donnell, T.; Ruchnewitz, D.; Geertz, D.; Bykov, Y.; Kodysh, J.; Oguntuyo, K. Y.; Roudko, V.; Hoyos, D.; Srivastava, K.; Kleiner, G.; Alshammary, H.; Karekar, N.; McClain, C.; Gopal, R.; Nie, K.; Del Valle, D.; Delbeau-Zagelbaum, D.; Rodriguez, D.; Setal, J.; The Mount Sinai COVID-19 Biobank Team, ; Carroll, E.; Wiesendanger, M.; Gulko, P.; Charney, A.; Merad, M.; Kim-Schulze, S.; Lee, B.; Wajnberg, A.; Simon, V.; Greenbaum, B. D.; Chowell, D.; Vabret, N.; Luksza, M.; Bhardwaj, N.
10.1101/2024.10.23.619918 — immunology — Posted on 2024-10-24
1332 Closed-loop modulation of remote hippocampal representations with neurofeedback
Coulter, M. E.; Gillespie, A. K.; Chu, J. P.; Denovellis, E. L.; Nguyen, T. T. K.; Liu, D.; Wadhwani, K.; Sharma, B.; Wang, K.; Deng, X.; Eden, U.; Kemere, C.; Frank, L. M.
10.1101/2024.05.08.593085 — neuroscience — Posted on 2024-10-24
1333 Roles of the 5-HT1A receptor in zebrafish responses to potential threat and in sociality
de Sousa, L. V. X. B.; de Oliveira, L. N.; Costa, B. P. D.; Lima-Maximino, M.; Veloso, V.; Maximino, C.
10.1101/2024.04.17.588464 — neuroscience — Posted on 2024-10-24
1335 EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes
Patel, N. P.; Shen, A.; Wada, Y.; Blair, M. A.; Mitchell, D. W.; Vanags, L. R.; Woo, S.; Ku, M. J.; Dauda, K. S.; Morris, W. A.; Yang, M.; Knollmann, B. C.; Roden, D. M.; Salem, J. E.; Glazer, A. M.; Kroncke, B. M.
10.1101/2024.10.21.619481 — pharmacology and toxicology — Posted on 2024-10-24
1337 Activation of Wnt/β-catenin signalling by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary gland basal cell adenoma
Wong, K.; Bishop, J. A.; Weinreb, I.; Motta, M.; Del Castillo Velasco-Herrera, M.; Bellacchio, E.; Ferreira, I.; van der Weyden, L.; Boccacino, J. M.; Rotundo, G.; Ciolfi, A.; Cheema, S.; Leon, R. O.; Offord, V.; Droop, A.; Vermes, I.; Allgaeuer, M.; Hyrcza, M.; Anderson, E.; Smith, K.; Aubain, N. d. S.; Mogler, C.; Stenzinger, A.; Arends, M. J.; Brenn, T.; Tartaglia, M.; Adams, D. J.
10.1101/2024.10.21.619442 — cancer biology — Posted on 2024-10-24
1338 WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer
Citron, F.; Ho, I.-L.; Balestrieri, C.; Liu, Z.; Yen, E.-Y. N.; Cecchetto, L.; Perelli, L.; Zhang, L.; Castillo Montanez, L. A.; Blazanin, N.; Dyke, C. A.; Shah, R.; Attanasio, S.; Srinivasan, S.; Chen, K.-C.; Chen, Z.; Scognamiglio, I.; Pham, N.; Khan, H.; Jiang, S.; Pan, J.; Vanderkruk, B.; Leung, C.; Mattohti, M.; Rai, K.; Chu, Y.; Wang, L.; Gao, S.; Deem, A. K.; Carugo, A.; Wang, H.; Yao, W.; Tonon, G.; Xiong, Y.; Lorenzi, P. L.; Bonini, C.; Zal, A.; Hoffman, B.; Giuliani, V.; Heffernan, T.; Jeter, C. R.; Lissanu, Y.; Genovese, G.; Di Pilato, M.; Viale, A.; Draetta, G. F.
10.1101/2024.10.21.619543 — cancer biology — Posted on 2024-10-24
1341 A simple action reduces high fat diet intake and obesity in mice
Barrett, M. R.; Pan, Y.; Murrell, C.; Karolczak, E. O.; Wang, J.; Fang, L.; Thompson, J. M.; Chang, S.; Casey, E.; Czarny, J.; So, W. L.; Reichenbach, A.; Stark, R.; Taghipourbibalan, H.; Penna, S. R.; McCullough, K. B.; Westbrook, S.; Matikainen-Ankeny, B.; Cazares, V. A.; Delevich, K.; Fobbs, W.; Maloney, S.; Sutton Hickey, A.; McCutcheon, J. E.; Andrews, Z.; Creed, M.; Krashes, M. J.; Kravitz, A. V.
10.1101/2024.10.01.615599 — animal behavior and cognition — Posted on 2024-10-24
1346 Transposable elements as evolutionary driving force to host shift in cactophilic Drosophila species
Oliveira, D. S. d.; Larue, A.; Nunes, W. V. B.; Sabot, F.; Bodelon, A.; Guerreiro, M. P. G.; Vieira, C.; Carareto, C. M.
10.1101/2024.03.27.587021 — evolutionary biology — Posted on 2024-10-24
1348 Global test of the enemy release hypothesis reveals similar patterns of herbivory across native and non-native plants
Galman, A.; Hahn, P. G.; Inouye, B. D.; Underwood, N.; Liu, Y.; Whitehead, S. R.; Wetzel, W. C.
10.1101/2024.10.21.619365 — ecology — Posted on 2024-10-24
1349 Fungal spore seasons advanced across the US over two decades of climate change
Wu, R.; Song, Y.; Head, J. R.; Katz, D. S.; Peay, K. G.; Shedden, K.; Zhu, K.
10.1101/2024.10.21.619107 — ecology — Posted on 2024-10-24
1350 ATR promotes mTORC1 activity via de novo cholesterol synthesis
Tangudu, N. K.; Grumet, A. N.; Fang, R.; Buj, R.; Cole, A. R.; Uboveja, A.; Amalric, A.; Yang, B.; Huang, Z.; Happe, C.; Sun, M.; Gelhaus, S. L.; MacDonald, M. L.; Hempel, N.; Snyder, N. W.; Kedziora, K. M.; Valvezan, A.; Aird, K. M.
10.1101/2023.10.27.564195 — cell biology — Posted on 2024-10-24
1351 Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways
Hickey, K. L.; Panov, A.; Whelan, E. M.; Schaefer, T.; Mizrak, A.; Kopito, R. R.; Baumeister, W.; Fernandez-Busnadiego, R.; Harper, W.
10.1101/2024.08.30.610524 — cell biology — Posted on 2024-10-24
1352 RBP4 functions as an antagonistic ligand of orphan DR6
Kim, T.; Lee, W. J.; Nguyen, T. N. C.; Jang, J.; Kim, K.; Kim, M.-S.; Seo, D.; Lee, Y.-S.; Lee, Y.-I.
10.1101/2024.10.21.619555 — molecular biology — Posted on 2024-10-24
1355 Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain
Silberfeld, A.; Roe, J. M.; Ellegood, J.; Lerch, J. P.; Qiu, L.; Kim, Y.; Lee, J. G.; Hopkins, W. D.; Grandjean, J.; Ou, Y.; Pourquie, O.
10.1101/2024.06.25.600709 — neuroscience — Posted on 2024-10-24
1356 NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks
Koonce, N. L.; Emerson, S. E.; Bhaskar, D.; Kuchroo, M.; Moyle, M. W.; Arroyo-Morales, P.; Martinez, N. V.; Krishnaswamy, S.; Mohler, W.; Colon-Ramos, D.
10.1101/2024.08.27.609993 — neuroscience — Posted on 2024-10-24
1362 Structural identification of the RY12 domain of RyR1 as an ADP sensor and the target of the malignant hyperthermia therapeutic dantrolene
Kim, K.; Li, H.; Yuan, Q.; Melville, Z.; Zalk, R.; Des Georges, A.; Frank, J.; Hendrickson, W. A.; Marks, A. R.; Clarke, O. B.
10.1101/2024.10.21.619409 — biophysics — Posted on 2024-10-24
1368 SEGUID v2: Extending SEGUID checksums for circular, linear, single- and double-stranded biological sequences
Pereira, H.; Silva, P. C.; Davis, W. M.; Abraham, L.; Babnigg, G.; Bengtsson, H.; Johansson, B.
10.1101/2024.02.28.582384 — bioinformatics — Posted on 2024-10-24
1370 Scale invariance of mechanical properties in the developing mammalian retina
Shelton, E. R.; Frischmann, M.; Brinkop, A. T.; James, R. M.; Serwane, F.
10.1101/2024.10.21.619491 — bioengineering — Posted on 2024-10-24
1371 Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale
Weinstein, E. N.; Gollub, M. G.; Slabodkin, A.; Gardner, C. L.; Dobbs, K.; Cui, X.-B.; Amin, A. N.; Church, G. M.; Wood, E. B.
10.1101/2024.09.13.612900 — bioengineering — Posted on 2024-10-24
1372 Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs
Kazmirczak, F.; Moon, R.; Vogel, N.; Tollison, W.; Lahti, M.; Carney, J.; Mendelson, J. B.; Markowski, T.; Higgins, L.; Murray, K.; Guerrero, C.; Prins, K.
10.1101/2024.04.24.590907 — biochemistry — Posted on 2024-10-24
1373 Mobility of Four Structural Regions Drives Isoform-Specific Properties of Plant LPOR
Gabruk, M.; Luszczynski, M.; Szafran, K.; Ogrodzinska, W.; Rubenstein, B. M.; da Silva, G. M.
10.1101/2024.10.21.619389 — biochemistry — Posted on 2024-10-24
1375 Estimating and correcting index hopping misassignments in single-cell RNA-seq data
Miao, L.; Collado, L.; Barkdull, S.; Saito, Y.; Jo, J.-H.; Han, J.; DellOrso, S.; Kelly, M. C.; Conlan, S.; Kong, H. H.; Brownell, I.
10.1101/2024.10.21.619353 — genomics — Posted on 2024-10-24
1376 Genomic biosurveillance of the kiwifruit pathogen Pseudomonas syringae pv. actinidiae biovar 3 reveals adaptation to selective pressures in New Zealand orchards
Hemara, L. M.; Hoyte, S. M.; Arshed, S.; Schipper, M. M.; Wood, P.; Marshall, S. L.; Andersen, M. T.; Patterson, H. R.; Vanneste, J. L.; Peacock, L.; Jayaraman, J.; Templeton, M. D.
10.1101/2024.10.21.616179 — genomics — Posted on 2024-10-24
1377 Targeted mutagenesis of specific genomic DNA sequences in animals for the in vivo generation of variant libraries
Falo-Sanjuan, J.; Diaz-Tirado, Y.; Turner, M. A.; Davis, J.; Medrano, C.; Haines, J.; McKenna, J.; Karshenas, A.; Eisen, M. B.; Garcia, H. G.
10.1101/2024.06.10.598328 — genetics — Posted on 2024-10-24
1380 Disentangling the effect of heritability and plasticity on Populus fremontii leaf reflectance across a temperature gradient
Seeley, M. M.; Thomson, E.; Allan, G. J.; Whitham, T. G.; Hultine, K.; Cooper, H. F.; Wiebe, B. C.; Asner, G. P.; Corbin, J. P.; Doughty, C. E.
10.1101/2024.10.21.619129 — ecology — Posted on 2024-10-24
1382 Mutation in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations
Klem, J. R.; Schwantes-An, T.-H.; Abreu, M.; Suttie, M.; Gray, R.; Vo, H.; Conley, G.; Foroud, T. M.; Wetherill, L.; CIFASD, ; Lovely, C. B.
10.1101/2023.06.28.546932 — developmental biology — Posted on 2024-10-24
1386 Systemic effects of oral tolerance improve the healing of several and concomitant wounds in different body parts
Nobrega, I. B. C.; Andrade, A. V. S.; Bikat, T. J. N.; Quintao, G. M.; Azevedo, G. M.; Valencia, K. F.; Costa, R. A.; Carvalho, C. R.
10.1101/2024.10.21.619410 — immunology — Posted on 2024-10-24
1390 Data-driven inference of Boolean networks from transcriptomes to predict cellular differentiation and reprogramming
Chevalier, S.; Becker, J.; Gui, Y.; Noël, V.; Su, C.; Jung, S.; Calzone, L.; Zinovyev, A.; del Sol, A.; Pang, J.; Sinkkonen, L.; Sauter, T.; Pauleve, L.
10.1101/2024.10.21.618706 — systems biology — Posted on 2024-10-24
1392 Aerobic capacity and exercise mediate protection against hepatic steatosis via enhanced bile acid metabolism.
Kugler, B. A.; Maurer, A.; Fu, X.; Franczak, E.; Ernst, N.; Schwartze, K.; Allen, J.; Li, T.; Crawford, P. A.; Koch, L. G.; Britton, S. L.; Burgess, S. C.; Thyfault, J.
10.1101/2024.10.21.619494 — physiology — Posted on 2024-10-24
1393 Blood pressure variability compromises vascular function in middle-aged mice
Mendiola, P. J.; O'Herron, P.; Xie, K.; Brands, M. W.; Bush, W.; Patterson, R. E.; DiStefano, V.; Filosa, J.
10.1101/2024.10.21.619509 — physiology — Posted on 2024-10-24
1394 Hydroxy polyethylene glycol: a solution to evade human pre-existing anti-PEG antibodies for efficient delivery
Ding, T.; Fu, J.; Yang, M.; Zhang, Z.; Ma, Y.; Wu, E.; Guo, Z.; Lin, S.; Wang, S.; Liu, X.; Wang, B.; Li, G.; Zhan, C.
10.1101/2024.10.21.619346 — pharmacology and toxicology — Posted on 2024-10-24
1395 A TEMPORAL MODEL OF TUMOR-IMMUNE DYNAMICS IN HIGH GRADE SEROUS OVARIAN CANCER
Egan, D.; Glennon, K.; Treacy, A.; Fabre, A.; McCormack, J.; Hill, S.; Morrison, R.; Liebler, D.; kolch, W.; Brennan, D.
10.1101/2024.10.21.619446 — cancer biology — Posted on 2024-10-24
1396 Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer
Bhattacharya, A.; Stutvoet, T. S.; Perla, M.; Loipfinger, S.; Jalving, M.; Reyners, A. K. L.; Vermeer, P. D.; Drapkin, R.; de Bruyn, M.; de Vries, E. G. E.; de Jong, S.; Fehrmann, R. S. N.
10.1101/2024.10.21.619015 — cancer biology — Posted on 2024-10-24
1397 Inhibition of PIM kinase in tumor associated macrophages suppresses inflammasome 1 activation and sensitizes prostate cancer to immunotherapy
Clements, A. N.; Casillas, A. L.; Flores, C. E.; Liou, H.; Toth, R. K.; Chauhan, S. S.; Sutterby, K.; Deshmukh, S. K.; Wu, S.; Xiu, J.; Farrell, A.; Radovich, M.; Nabhan, C.; Heath, E. I.; McKay, R. R.; Subah, N.; Centuori, S.; Wheeler, T. J.; Cress, A. E.; Rogers, G. C.; Wilson, J. E.; Recio-Boiles, A.; Warfel, N. A.
10.1101/2024.10.21.618756 — cancer biology — Posted on 2024-10-24
1399 The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma
Lightfuss, O. B.; Kumar, P.; Li, L.; Shastri, T.; Newsam, A. D.; Manara, P.; Alaoui, A. Y.; Parets, D. E. H.; Younes, P. A.; Chahar, D.; Arumov, A.; Coughlin, C. A.; Williams, I. P.; Fattakhov, N.; Martinez, A. B.; Landgren, O.; Schurer, S. C.; Lemmon, V.; Maura, F.; Bilbao, D.; Feng, Y.; Al-Ali, H.; Schatz, J. H.
10.1101/2024.10.21.619489 — cancer biology — Posted on 2024-10-24
1400 Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis
Jones, M. G.; Sun, D.; Min, K. H.; Colgan, W. N.; Tian, L.; Weir, J. A.; Chen, V. Z.; Koblan, L. W.; Yost, K. E.; Mathey-Andrews, N.; Russell, A. J. C.; Stickels, R. R.; Balderrama, K. S.; Rideout, W. M.; Chang, H. Y.; Jacks, T.; Chen, F.; Weissman, J. S.; Yosef, N.; Yang, D.
10.1101/2024.10.21.619529 — cancer biology — Posted on 2024-10-24
1402 Deciphering molecular determinants of GPCR-G protein receptor interactions by complementary integrative structural biology methods
Castel, J.; Botzanowski, T.; Brooks, I.; Frechard, A.; Bey, G.; Schroeter, M.; Del Nero, E.; Debaene, F.; Ciesielski, F.; Zeyer, D.; Cianferani, S.; Morales, R.
10.1101/2024.10.21.619395 — biophysics — Posted on 2024-10-24
1404 Revealing the hidden sequence distribution of epitope-specific TCR repertoires and its influence on machine learning model performance
Gielis, S.; Chernigovskaya, M.; Pavlovic, M.; Van Deuren, V.; Vandoren, R.; Valkiers, S.; Laukens, K.; Greiff, V.; Meysman, P.
10.1101/2024.10.21.619364 — bioinformatics — Posted on 2024-10-24
1406 Comparative study of Ergosterol and 7-dehydrocholesterol and their Endoperoxides: Generation, Identification and Impact in Phospholipid Membranes and Melanoma Cells
Yukuyama, M. N.; Fabiano, K. C.; Inague, A.; Uemi, M.; Lima, R. S.; Diniz, L. R.; Oliveira, T. E.; Iijima, T. S.; Faria, H. O. F.; Santos, R. S.; Nolf, M. F. V.; Chaves-Filho, A. B.; Yoshinaga, M. Y. B.; Junqueira, H. C.; Di Mascio, P.; Baptista, M. d. S.; Miyamoto, S.
10.1101/2024.10.21.619400 — biochemistry — Posted on 2024-10-24
1410 Abundant genetic variation is retained in many laboratory schistosome populations
Jutzeler, K. S.; Platt, R. N.; Diaz, R.; Morales, M.; Le Clec'h, W.; Chevalier, F.; Anderson, T. J.
10.1101/2024.10.21.619418 — genomics — Posted on 2024-10-24
1413 The dual trxG/PcG protein ULTRAPETALA1 modulates H3K27me3 and directly enhances POLYCOMB REPRESSIVE COMPLEX 2 activity for fine-tuned reproductive transitions
Geshkovski, V.; Engelhorn, J.; Izquierdo, J.-B.; Laroussi, H.; Thouly, C.; Turchi, L.; Le Masson, M.; Thevenon, E.; Petitalot, A.; Simon, L.; Desset, S.; Michl-Holzinger, P.; Parrinello, H.; Grasser, K. D.; Probst, A.; Margueron, R.; Vachon, G.; Kadlec, J.; CARLES, C. C.
10.1101/2024.10.21.619451 — genetics — Posted on 2024-10-24
1419 Tissue-adapted Tregs harness inflammatory signals to promote intestinal repair from therapy-related injury
Fischer, J. C.; Goettert, S.; Heinrich, P.; Walther, C. N.; Fan, K.; Eisenkolb, G.; Nefzger, S. M.; Giller, M.; Khalid, O.; Timnik, V. R.; Jarosch, S.; Klostermeier, L.; Engleitner, T.; Strieder, N.; Gebhard, C.; Diederich, S.; Schmid, N. A.; Lansink Rotgerink, L.; Joachim, L.; Ghimire, S.; Remke, M.; Steiger, K.; Oellinger, R.; Rad, R.; Wolff, D.; Feuerer, M.; Hoffmann, P.; Edinger, M.; Rehli, M.; Tschurtschenthaler, M.; Kepp, O.; Kroemer, G.; Thiele Orberg, E.; Combs, S. E.; Herr, W.; Bassermann, F.; Busch, D. H.; Holler, E.; Heidegger, S.; Poeck, H.
10.1101/2024.10.21.617518 — immunology — Posted on 2024-10-24
1423 Pipeasm: a tool for automated large chromosome-scale genome assembly and evaluation
Silva, B. M.; Trindade, F. d. J.; Canesin, L. E. C.; Souza, G. B. S.; Aleixo, A.; Nunes, G. L.; Oliveira, R. R. M.
10.1101/2024.10.21.598381 — bioinformatics — Posted on 2024-10-24
1424 Immune-like glycan-sensing and horizontally-acquired glycan-processing orchestrate host control in a microbial endosymbiosis
Jenkins, B. H.; Kilias, E. S.; Savory, F. R.; Soerensen, M. E. S.; Poirier, C.; Attah, V.; Drew, G. C.; Galindo, L. J.; Leonard, G.; Cameron, D. D.; Brockhurst, M. A.; Milner, D. S.; Richards, T. A.
10.1101/2024.09.14.613017 — evolutionary biology — Posted on 2024-10-24
1425 Structural compromise in spiking cortex and connected networks
Sahlas, E.; Avigdor, T.; Ngo, A.; Royer, J.; Lariviere, S.; Chen, J.; Xie, K.; Wang, Y.; Lam, J.; Rodriguez-Cruces, R.; Arafat, T.; Pana, R.; Bernasconi, A.; Bernasconi, N.; Frauscher, B.; Bernhardt, B.
10.1101/2024.10.19.619207 — neuroscience — Posted on 2024-10-24
1427 Drivers of plant-associated invertebrate community structure in West-European coastal dunes
Van De Walle, R.; Dahirel, M.; Langeraert, W.; Benoit, D.; Vantieghem, P.; Vandegehuchte, M. L.; Massol, F.; Bonte, D.
10.1101/2024.06.24.600350 — ecology — Posted on 2024-10-24
1428 Evolutionary rescue during extreme drought
Anstett, D. N.; Anstett, J.; Sheth, S. N.; Moxley, D.; Jahani, M.; Huang, K.; Todesco, M.; Jordan, R.; Lazaro-Guevara, J. M.; Rieseberg, L. H.; Angert, A. L.
10.1101/2024.10.24.619808 — evolutionary biology — Posted on 2024-10-24
1430 Dnajc3 (HSP40) Modulates Axon Regeneration in the Mouse Optic Nerve
Wang, J.; Li, Y.; Struebing, F. L.; Jardines, S.; Lin, S.-T.; Lin, F.; Geisert, E. E.
10.1101/2024.10.08.617251 — neuroscience — Posted on 2024-10-24
1432 NINJ1 is activated by calcium-driven plasma membrane lipid scrambling during lytic cell death
Borges, J. P.; Wang, Y.; David, L.; Volchuk, A.; Martins, B.; Cai, R.; Wu, H.; Freeman, S. A.; Goldenberg, N. M.; SALTER, M. W.; Steinberg, B. E.
10.1101/2024.10.23.619800 — cell biology — Posted on 2024-10-24
1433 New therapeutic combination to enhance endocytosis of antibodies and nucleic-acid aptamers targeting EGFR in glioblastoma cells
Cruz Da Silva, E.; D'Ancona, C.; Justiniano, H.; Calco, V.; Sensoy, D.; Villa, P.; Vauchelles, R.; Lehmann, M.; Choulier, L.
10.1101/2024.10.22.617611 — cell biology — Posted on 2024-10-24
1436 Stress-hardening behaviour of biofilm streamers
Savorana, G.; Redaelli, T.; Truzzolillo, D.; Cipelletti, L.; Secchi, E.
10.1101/2024.10.04.616620 — biophysics — Posted on 2024-10-24
1437 Dynamics and Regulatory Roles of RNA m6A Methylation in Unbalanced Genomes
Zhang, S.; Wang, R.; Luo, K.; Gu, S.; Liu, X.; Wang, J.; Zhang, L.; Sun, L.
10.1101/2024.07.05.602246 — genomics — Posted on 2024-10-24
1439 Number and proportion of P. falciparum gametocytes vary from acute infection to chronic parasite carriage despite unaltered sexual commitment rate
van Dijk, H.; Kampmann, M.; Ferreira Lima, N.; Gabel, M.; Dabbas, U.; Doumbo, S.; Cisse, H.; Li, S.; Jeninga, M.; Thomson Luque, R.; Doumtabe, D.; Petter, M.; Kayentao, K.; Ongoiba, A.; Bousema, T.; Crompton, P. D.; Traore, B.; Graw, F.; Portugal, S.
10.1101/2021.11.05.467456 — microbiology — Posted on 2024-10-24
1444 Tailocin-mediated interactions in Soft Rot Pectobacteriaceae
Borowicz, M.; Krzyzanowska, D. M.; Sobolewska, M.; Narajczyk, M.; Mruk, I.; Czaplewska, P.; Pedron, J.; Barny, M.-A.; Yves Canto, P.; Dziadkowiec, J.; Czajkowski, R.
10.1101/2024.09.28.615580 — microbiology — Posted on 2024-10-24
1447 Depletion of BBSome Subunits Alters Receptor Endocytosis and Promotes EMT via TGF-β Signaling
Solarat, C.; Barra-Carneiro, J.; Vila-Almuina, S.; Barbeito, P.; Holm, M. S.; Gammoh, N.; Christensen, S. T.; Valverde, D.
10.1101/2024.10.23.619933 — molecular biology — Posted on 2024-10-24
1449 Variable Presence of an Evolutionarily New Brain Structure is Related to Trait Impulsivity
Willbrand, E. H.; Maboudian, S. A.; Elliott, M. V.; Kellerman, G. M.; Johnson, S. L.; Weiner, K. S.
10.1101/2024.10.23.619912 — neuroscience — Posted on 2024-10-24
1450 WITHDRAWN: Signal Transduction and Kinase Control in Nanodisc Reconstituted E. coli Aerotaxis Receptor
Maschmann, Z. A.; Chandrasekaran, S.; Anderson, E. T.; Fu, Q.; Freed, J. H.; Crane, B. R.
10.1101/2023.03.13.532224 — biophysics — Posted on 2024-10-24
1453 Deep Active Learning for Robust Biomedical Segmentation
Arikan, M.; Sallo, F.; Montesel, A.; Ahmed, H.; Hagag, A.; Book, M.; Faatz, H.; Cicinelli, M.; Meshkinfamfard, S.; Ongun, S.; Dubis, A.; Lilaonitkul, W.
10.1101/2023.03.28.534521 — bioengineering — Posted on 2024-10-24
1455 Logging alters tropical forest structure, while conversion to agriculture reduces biodiversity and functioning
Marsh, C. J.; Turner, E. C.; Blonder, B. W.; Bongalov, B.; Both, S.; Cruz, R. S.; Elias, D. M. O.; Hemprich-Bennett, D.; Jotan, P.; Kemp, V.; Kritzler, U. H.; Milne, S.; Milodowski, D. T.; Mitchell, S. L.; Montoya Pillco, M.; Nunes, M. H.; Riutta, T.; Robinson, S. J. B.; Slade, E. M.; Bernard, H.; Burslem, D. F. R. P.; Chung, A. Y. C.; Clare, E. L.; Coomes, D. A.; Davies, Z. G.; Edwards, D. P.; Johnson, D.; Kratina, P.; Malhi, Y.; Majalap, N.; Nilus, R.; Ostle, N. J.; Rossiter, S. J.; Struebig, M. J.; Tobias, J. A.; Williams, M.; Ewers, R. M.; Lewis, O. T.; Reynolds, G.; Teh, Y. A.; Hector, A.
10.1101/2022.12.15.520573 — ecology — Posted on 2024-10-24
1459 Comparative study on the virulence of mycobacteriophages
Rubino, I.; Guerrero-Bustamante, C. A.; Harrison, M.; Co, S.; Tetreau, I.; Ordoubadi, M.; Larsen, S. E.; Coler, R. N.; Vehring, R.; Hatfull, G. E.; Sauvageau, D.
10.1101/2024.10.23.619922 — microbiology — Posted on 2024-10-24
1460 Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replication
Owino, C. O.; Narmada, B. C.; Yi Lin, G.; Poh Kim Aw, P.; Ganesh, N.; Siying, J. T.; Plissonnier, M.-L.; Matan, T. T.; Shirgaonkar, N.; Bifani, J. P.; Levrero, M.; Periyasamy, G.; Lim, S. G.; DasGupta, R.
10.1101/2024.10.23.619969 — microbiology — Posted on 2024-10-24
1464 Molecular fingerprints of cell size sensing and mating type differentiation in pennate diatoms
Belisova, D.; Bilcke, G.; Audoor, S.; D'hondt, S.; De Veylder, L.; Vandepoele, K.; Vyverman, W.
10.1101/2024.04.15.589526 — plant biology — Posted on 2024-10-24
1465 Non-canonical Telomerase Reverse Transcriptase Controls Osteogenic Reprogramming of Aortic Valve Cells Through STAT5
Cuevas, R. A.; Hortells, L.; Chu, C.; Wong, R.; Crane, A.; Boufford, C.; Regan, C.; Moorhead, W.; Bashline, M.; Parwal, A.; Parise, A.; Behzadi, P.; Gurkar, A.; Bruemmer, D.; Sembrat, J.; Sultan, I.; Gleason, T.; Billaud, M.; St. Hilaire, C.
10.1101/2022.08.23.504425 — pathology — Posted on 2024-10-24
1468 Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model
Older, E. A.; Mitchell, M. K.; Campbell, A.; Lian, X.; Madden, M.; Wang, Y.; van de Wal, L. E.; Zaw, T.; VanderVeen, B. N.; Tatum, R.; Murphy, E. A.; Chen, Y.-H.; Fan, D.; Ellermann, M.; Li, J.
10.1101/2024.10.23.619966 — biochemistry — Posted on 2024-10-24
1469 Bioorthogonal cyclopropenones for investigating RNA structure
Chen, S.; Sibley, C. D.; Latifi, B.; Balaratnam, S.; Dorn, R. S.; Luptak, A.; Schneekloth, J. S.; Prescher, J. A.
10.1101/2024.10.22.619649 — biochemistry — Posted on 2024-10-24
1470 Low fidelity DNA polymerase IV accelerates genome evolution in Pseudomonas aeruginosa
Castell, S.; Fernandez, C.; Tumas, I.; Margara, L.; Miserendino, M.; Ceschin, D.; Pezza, R.; Monti, M.
10.1101/2024.10.22.619742 — genomics — Posted on 2024-10-24
1471 AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
Park, J.; Choi, W.; Seong, D. Y.; Jeong, S.; Lee, J. Y.; Park, H. J.; Chung, D. S.; Yi, K.; Kim, U.; Yoon, G.-Y.; Kim, H.; Kim, T.; Ko, S.; Min, E. J.; Cho, H.-S.; Cho, N.-H.; Hong, D.
10.1101/2024.06.14.598983 — genomics — Posted on 2024-10-24
1472 Mapping-based genome size estimation
Natarajan, S.; Gehrke, J.; Pucker, B.
10.1101/607390 — genomics — Posted on 2024-10-24
1473 Contextualising transcription factor binding during embryogenesis using natural sequence variation
Sigalova, O. M.; Forneris, M.; Stojanovska, F.; Zhao, B.; Viales, R. R.; Rabinowitz, A.; Hamal, F.; Ballester, B.; Zaugg, J. B.; Furlong, E. E.
10.1101/2024.10.24.619975 — genetics — Posted on 2024-10-24
1477 Simulated larvae dispersion of the invasive sun-coral (Tubastrea spp.) along Rio de Janeiro's coast: the role of submesoscale filaments on offshore transport and connectivity
Calado, L.; Cosensa, B.; Moraes, F. L. P. d.; Dias Luko, C.; Mizrahi, D.; Xavier, F. C.; Batista, D.; Domingos, R.; Calazans, S.; Araujo, F.; Coutinho, R.
10.1101/2024.10.23.619824 — ecology — Posted on 2024-10-24
1479 Maternal adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero
Murphy, M.; Fallahi, S.; Dumolt, J. H.; Houck, J. A.; Vaughan, O. R.; Moore, L. G.; Julian, C. G.; Powell, T. L.; Lorca, R. A.
10.1101/2024.09.21.612123 — developmental biology — Posted on 2024-10-24
1480 HuR-dependent expression of RyR2 contributes to calcium-mediated thermogenesis in brown adipocytes
Guarnieri, A. R.; Anthony, S. R.; Acharya, P.; Wen, B. Y.; Lanzillotta, L.; Gavin, R.; Tranter, M.
10.1101/2024.10.22.619637 — molecular biology — Posted on 2024-10-24
1482 IOP-induced blood-retinal barrier compromise contributes to RGC death in glaucoma
Zhang, C.; Simon, M.; Lim, H.; Tolman, N. G.; Horbal, L.; Juarez, F. A.; Bhandari, A.; Montgomery, C.; John, S. W. M.
10.1101/2024.10.15.618539 — neuroscience — Posted on 2024-10-24
1486 Alzheimer's disease-associated protective variant Plcg2-P522R modulates peripheral macrophage function in a sex-dimorphic manner
Staley, H. A.; Jernigan, J.; Bolen, M. L.; Titus, A. M.; Neighbarger, N. K.; Cole, C.; Menees, K. B.; Wallings, R. L.; Tansey, M. G.
10.1101/2024.05.28.596275 — neuroscience — Posted on 2024-10-24
1487 Glia control experience-dependent plasticity in an olfactory critical period
Leier, H. C.; Foden, A. J.; Jindal, D. A.; Wilkov, A. J.; Van der Linden Costello, P.; Vanderzalm, P. J.; Coutinho-Budd, J.; Tabuchi, M.; Broihier, H. T.
10.1101/2024.07.05.602232 — neuroscience — Posted on 2024-10-24
1488 Generalizable Neural Models of Emotional Engagement and Disengagement
Nanni Zepeda, M.; Evans, T.; Jagger-Rickels, A.; Raz, G.; Hendler, T.; Fan, Y.; Grimm, S.; Walter, M.; Esterman, M.; Zuberer, A.
10.1101/2024.02.15.579332 — neuroscience — Posted on 2024-10-24
1489 Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
Maristany, M. J.; Aguirre Gonzalez, A.; Espinosa, J. R.; Huertas, J.; Collepardo-Guevara, R.; Joseph, J. A.
10.1101/2023.06.14.543914 — biophysics — Posted on 2024-10-24
1491 PACT prevents aberrant activation of PKR by endogenous dsRNA without sequestration
Ahmad, S.; Zou, T.; Zhao, L.; Wang, X.; Hwang, J.; Davydenko, A.; Buchumenski, I.; Zhuang, P.; Fishbein, A. R.; Capcha-Rodriguez, D.; Orgel, A.; Levanon, E. Y.; Myong, S.; Chou, J.; Meyerson, M.; Hur, S.
10.1101/2024.10.23.619951 — biochemistry — Posted on 2024-10-24
1493 mm2-gb: GPU Accelerated Minimap2 for Long Read DNA Mapping
Dong, J.; Liu, X.; Sadasivan, H.; Sitaraman, S.; Narayanasamy, S.
10.1101/2024.03.23.586366 — genomics — Posted on 2024-10-24
1494 Mosaic of Somatic Mutations in Earth's Oldest Living Organism, Pando
Pineau, R.; Mock, K. E.; Morris, J. L.; Kraklow, V.; Brunelle, A.; Pageot, A.; Ratcliff, W. C.; Gompert, Z.
10.1101/2024.10.19.619233 — evolutionary biology — Posted on 2024-10-24
1497 Toward a unified theory of microbially-mediated invasion
Martignoni, M. M.; Garnier, J. M.; Tyson, R. C.; Harris, K. D.; Kolodny, O.
10.1101/2024.01.18.576278 — ecology — Posted on 2024-10-24
1498 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.
10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-10-24
1499 Anxious/depressed individuals exhibit disrupted frontotemporal synchrony during cognitive conflict encoding
Shekara, A.; Ross, A.; Soper, D. J.; Paulk, A. C.; Cash, S. S.; Shear, P. K.; Sheehy, J. P.; Basu, I.
10.1101/2024.10.10.617540 — neuroscience — Posted on 2024-10-24
1500 α-Synuclein Strain Dynamics Correlate with Cognitive Shifts in Parkinson's Disease
Gadhave, K.; Xu, E.; Wang, N.; Zhang, X.; Deyell, J.; Yang, J.; Wang, A.; Cha, Y.; Kumbhar, R.; Liu, H.; Niu, L.; Chen, R.; Zhang, S.; Bakker, C.; Jin, L.; Liang, Y.; Ying, M.; Dawson, V. L.; Dawson, T. M.; Rosenthal, L. S.; Mao, X.
10.1101/2024.10.22.619694 — neuroscience — Posted on 2024-10-24
1503 Selective expansion of motor cortical projections in the evolution of vocal novelty
Isko, E. C.; Harpole, C. E.; Zheng, X. M.; Zhan, H.; Davis, M. B.; Zador, A. M.; Banerjee, A.
10.1101/2024.09.13.612752 — neuroscience — Posted on 2024-10-24
1505 Enhancing Challenging Target Screening via Multimodal Protein-Ligand Contrastive Learning
Wang, Z.; Wang, Z.; Yang, M.; Pang, L.; Nie, F.; Liu, S.; Gao, Z.; Zhao, G.; Ji, X.; Huang, D.; Zhu, Z.; Li, D.; Yuan, Y.; Zheng, H.; Zhang, L.; Ke, G.; Wang, D.; Yu, F.
10.1101/2024.08.22.609123 — bioinformatics — Posted on 2024-10-24
1508 Multigenerational Proteolytic Inactivation of Restriction Upon Subtle Genomic Hypomethylation
Shmidov, E.; Villani, A.; Mendoza, S. D.; Avihu, E.; Lebenthal-Loinger, I.; Karako-Lampert, S.; Shoshani, S.; Ye, C.; Wang, Y.; Yan, H.; Tang, W.; Bondy-Denomy, J.; Banin, E.
10.1101/2024.10.21.619520 — microbiology — Posted on 2024-10-23
1509 Pseudomonas aeruginosa Alkyl Quinolone Response is dampened by Enterococcus faecalis
Fink, M. M.; Weaver, A. A.; Parmar, D.; Paczkowski, J.; Li, L.; Klaers, M. K.; Junker, E. A.; Jarocki, E. A.; Sweedler, J. V.; Shrout, J. D.
10.1101/2024.10.23.619906 — microbiology — Posted on 2024-10-23
1510 Evidence for high-frequency parallel evolution in virulent A. baumannii cultures
Mclaughlin, J.; Tobin, J. K.; Hao, J.; Bushnell, R. V.; MacLeod, D. A.; Wiggins, T. J.; Zurawski, D. V.; Tobin, G. J.; Dollery, S. J.
10.1101/2024.10.22.618551 — microbiology — Posted on 2024-10-23
1511 Xenosiderophore transporter gene expression and clade-specific filamentation in Candida auris killifish infection
Gifford, H.; Bedekovic, T.; Helmstetter, N.; Gregory, J.; Ma, Q.; Brand, A. C.; Wilson, D.; Rhodes, J.; Ramsdale, M.; Kudoh, T.; Farrer, R. A.
10.1101/2024.10.22.619744 — microbiology — Posted on 2024-10-23
1514 Endogenous neuronal DNA double-strand breaks are not sufficient to drive brain aging and neurodegeneration
Cohen, S.; Cheradame, L.; Pratt, K.; Collins, S.; Barillas, A.; Carlson, A.; Ramani, V.; Legube, G.; Villeda, S.; Mullins, D.; Schwer, B.
10.1101/2024.10.22.619740 — neuroscience — Posted on 2024-10-23
1518 Pre-existing H1N1 immunity reduces severe disease with bovine H5N1 influenza virus
Le Sage, V.; Werner, B. D.; Merrbach, G. A.; Petnuch, S. E.; O'Connell, A. K.; Simmons, H. C.; McCarthy, K. R.; Reed, D. S.; Moncla, L. H.; Bhavsar, D. H.; Krammer, F.; Crossland, N.; McElroy, A.; Duprex, W. P.; Lakdawala, S.
10.1101/2024.10.23.619881 — microbiology — Posted on 2024-10-23
1520 Soil properties in agricultural systems affect microbial genomic traits
Goodall, T. I.; Busi, S. B.; Griffiths, R.; Jones, B. A.; Pywell, R.; Richards, A.; Nowakowski, M.; Read, D.
10.1101/2024.10.23.619851 — microbiology — Posted on 2024-10-23
1521 Comparative proteomics of biofilm development in Pseudoalteromonas tunicata discovers a distinct family of Ca2+-dependent adhesins
Ali, S.; Stavropoulos, A.; Jenkins, B.; Graves, S.; Che, G.; Cheng, J.; Tan, H.; Wei, X.; Egan, S.; Neufeld, J. D.; Eckhard, U.; Charles, T. C.; Doxey, A. C.
10.1101/2024.10.22.619756 — microbiology — Posted on 2024-10-23
1525 Immune History Modifies Disease Severity to HPAI H5N1 Clade 2.3.4.4b Viral Challenge
Brigleb, P. H.; Sharp, B.; Roubidoux, E. K.; Meliopoulos, V. A.; Tan, S.; Livingston, B.; Morris, D. R.; Ripperger, T.; Lazure, L.; Balaraman, V.; Thompson, A.; Kleinhenz, K.; Dimitrov, K. M.; Thomas, P.; Schultz-Cherry, S.
10.1101/2024.10.23.619695 — microbiology — Posted on 2024-10-23
1526 Strengthening Phage Resistance of Streptococcus thermophilus by Leveraging Complementary Defense Systems
Leprince, A.; Lefrancois, J.; Magill, D.; Horvath, P.; Romero, D.; Rousseau, G. M.; Moineau, S.
10.1101/2024.10.22.618286 — microbiology — Posted on 2024-10-23
1527 Rewired type I IFN signaling is linked to age-dependent differences in COVID-19
Petrov, L.; Brumhard, S.; Wisniewski, S.; Georg, P.; Hillus, D.; Hiller, A.; Astaburuaga-Garcia, R.; Bluethgen, N.; Wyler, E.; Vogt, K.; Dey, H.-P.; von Stillfried, S.; Iwert, C.; Buelow, R. D.; Maerkl, B.; Maas, L.; Langner, C.; Meyer, T.; Loske, J.; Eils, R.; Lehmann, I.; Ondruschka, B.; Ralser, M.; Trimpert, J.; Boor, P.; Bedoui, S.; Meisel, C.; Mall, M. A.; Corman, V. M.; Sander, L. E.; Roehmel, J.; Sawitzki, B.
10.1101/2024.10.23.619479 — immunology — Posted on 2024-10-23
1529 Enhanced immune evasion of SARS-CoV-2 KP.3.1.1 and XEC through NTD glycosylation
Liu, J.; Yu, Y.; Jian, F.; Yang, S.; Song, W.; Wang, P.; Yu, L.; Shao, F.; Cao, Y.
10.1101/2024.10.23.619754 — immunology — Posted on 2024-10-23
1532 Decoding the transcriptomic signatures of psychological trauma in human cortex and amygdala
Hicks, E. M.; Seah, C.; Deans, M.; Lee, S.; Johnston, K. J.; Cote, A.; Ciarcia, J.; Chakka, A.; Collier, L.; Holtzheimer, P.; Young, K. A.; Traumatic Stress Brain Research Group, ; Brennand, K.; Nestler, E. J.; Girgenti, M. J.; Huckins, L. M.
10.1101/2024.10.23.619681 — neuroscience — Posted on 2024-10-23
1534 ALS-associated RNA binding proteins converge on UNC13A transcription through regulation of REST
Watanabe, Y.; Suzuki, N.; Nakagawa, T.; Hosogane, M.; Akiyama, T.; Warita, H.; Aoki, M.; Nakayama, K.
10.1101/2024.10.22.619761 — neuroscience — Posted on 2024-10-23
1535 The role of dopaminergic, cholinergic and noradrenergic networks in hyposmia in Parkinson's disease
Perot, J.-B.; Kozlowski, E.; Fraysse, A.; Ouarab, S.; Valabregue, R.; Rebbah, S.; Lejeune, F.-X.; Massy, E.; Gaurav, R.; Arnulf, I.; Corvol, J.-C.; Vidailhet, M.; Pyatigorskaya, N.; Gallea, C.; Lehericy, S.
10.1101/2024.10.23.619791 — neuroscience — Posted on 2024-10-23
1536 Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster
Gunnala, S.; Harrison, A.; Juba, A.; Ashcraft, P.; Bottiglieri, T.; Buhlman, L. M.; Jadavji, N. M.
10.1101/2024.10.23.619884 — neuroscience — Posted on 2024-10-23
1539 Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations
Swanson, R. A.; Chinigo, E.; Levenstein, D.; Voroslakos, M.; Mousavi, N.; Wang, X.-J.; Basu, J.; Buzsaki, G.
10.1101/2024.10.23.619879 — neuroscience — Posted on 2024-10-23
1540 Convergent olfactory circuits for courtship in Drosophila revealed by ds-Tango
Fisher, J. D.; Crown, A. M.; Sorkac, A.; Martinez-Machado, S.; Snell, N. J.; Vishwanath, N.; Monje, S.; Vo, A.; Wu, A. H.; Mosneanu, R. A.; Okoro, A. M.; Savas, D.; Nkera, B.; Iturralde, P.; Kumari, A.; Chou-Freed, C.; Hartmann, G. G.; Talay, M.; Barnea, G.
10.1101/2024.10.23.619891 — neuroscience — Posted on 2024-10-23
1542 The YTHDF Proteins Shape the Brain Gene Signatures of Alzheimer's Disease
Tasaki, S.; Avey, D. R.; Kearns, N. A.; Iatrou, A.; Yu, C.; De Tissera, S.; Vyas, H.; Xu, J.; Flood, D. J.; Rothamel, K.; Wingo, A. P.; Wingo, T. S.; Seyfried, N. T.; De Jager, P. L.; Yeo, G.; Gaiteri, C.; Bennett, D. A.; Wang, Y.
10.1101/2024.10.23.619425 — neuroscience — Posted on 2024-10-23
1545 Sex-biased effect of sodium leak channel NALCN deletion in striatal Drd2 spiny projection neurons
Castell, L.; Naon, C.; Rogliardo, A.; Makrini, L.; Avrillon, M.; Mignon, A.; Bernat, C.; Lory, P.; Bertaso, F.; Monteil, A.; Bosch-Bouju, C.; Valjent, E.
10.1101/2024.10.23.619832 — neuroscience — Posted on 2024-10-23
1546 Cortex-wide characterization of decision-making neural dynamics during spatial navigation
Haley, S. P.; Surinach, D. A.; Nietz, A. K.; Carter, R. E.; Zecker, L. S.; Popa, L. S.; Kodandaramaiah, S. B.; Ebner, T. J.
10.1101/2024.10.23.619896 — neuroscience — Posted on 2024-10-23
1548 SC10X/U: A High-density Electrode System for Non-Invasive Recording of Neural Activity of the Cervical Spinal Cord
Mehra, P.; Metzger, M.; Bista, S.; Plaitano, S.; Giglia, E.; Nash, L.; Domhnaill, E. M.; Mitchell, M.; Bede, P.; Lowery, M. M.; Muthuraman, M.; Hardiman, O.; Nasseroleslami, B.
10.1101/2024.10.23.619533 — neuroscience — Posted on 2024-10-23
1549 Type 2 diabetes remodels collateral circulation and promotes leukocyte adhesion following ischemic stroke
Sato, Y.; Li, Y.; Kato, Y.; Kanoke, A.; Sun, Y. J.; Nishijima, Y.; Wang, R. K.; Stryker, M.; Endo, H.; Liu, J.
10.1101/2024.10.23.619748 — neuroscience — Posted on 2024-10-23
1550 Modulation of leg trajectory by transcranial magnetic stimulation during walking
Bourgeois, H.; Guay-Hottin, R.; Meftah, E. M.; Martinez, M.; Bonizzato, M.; Barthelemy, D.
10.1101/2024.10.23.619051 — neuroscience — Posted on 2024-10-23
1551 A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices
Gonzalez, V. V.; Malvaez, M.; Yeghikian, A.; Wissing, S.; Sharpe, M.; Wassum, K. M.; Izquierdo, A.
10.1101/2024.10.23.619920 — neuroscience — Posted on 2024-10-23
1554 Size Selection of Giant Unilamellar Vesicles (GUVs) via Modified cDICE Method
Chen, A.; Gat, S.; Ohana, L.; Ekymov, E.; Tsori, Y.; Bernheim-Groswasser, A.
10.1101/2024.10.23.619772 — synthetic biology — Posted on 2024-10-23
1556 Imaging of live bacterial whole-cell biosensors illuminates spatial sialic acid availability within the inflamed mammalian gut
Carreno, D.; Robinson, C. M.; Jackson, R.; Li, P.; Nunes, V.; Palma-Duran, S. A.; Nye, E.; MacRae, J. I.; Riglar, D. T.
10.1101/2024.10.23.619804 — synthetic biology — Posted on 2024-10-23
1563 The ReAct project: Analysis of data from 23 different laboratories to characterise DNA recovery given two sets of activity level propositions
Gill, P.; Fonnelop, A. E.; Hicks, T.; Xenophontos, S.; Cariolou, M.; van Oorschot, R.; Buckel, I.; Sukser, V.; Papic, S.; Merkas, S.; Kostic, A.; Marques Pereira, A.; Teutsch, C.; Forsberg, C.; Haas, C.; Petkovski, E.; Hass, F.; Masek, J.; Stosic, J.; Lee, Y. S.; Syn, C. K.-C.; Groombridge, L.; Trimborn, M.; Hadjivassiliou, M.; Breathnach, M.; Novackova, J.; Parson, W.; Hatzer-Grubwieser, P.; Pietikoinen, S.; Joas, S.; Willuweit, S.; Grethe, S.; Milicevic, T.; Hasselqvist, T.; Kallupurackal, V.; Stenzl, V.; Jansson, S.; Glocker, I.; Brunck, S.; Nyhagen, K.; Dyve Lingelem, A. B.; Autere, H.; Th
10.1101/2024.10.10.617148 — genetics — Posted on 2024-10-23
1564 Quantitative Proteomics Identifies Conserved Proteins and Altered Regulation of Mucin-16 in Low Grade Serous Ovarian Cancers
Tarney, C. M.; Mhawech-Fauceglia, P.; Ogata, J. D.; Oliver, J.; Abulez, T.; Branton, P. A.; Movahedi-Lankarani, S.; Hood, B. L.; Conrads, K. A.; Rosalik, K.; Wong, K.-K.; Gershenson, D. M.; Lee, S.; Sood, A. K.; Bast, R. C.; Darcy, K. M.; Phippen, N. T.; Maxwell, G. L.; Conrads, T. P.; Bateman, N. W.
10.1101/2024.04.29.591278 — cancer biology — Posted on 2024-10-23
1566 Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing
van der Toorn, W.; Bohn, P.; Liu-Wei, W.; Olguin-Nava, M.; Smyth, R. P.; von Kleist, M.
10.1101/2024.07.22.604276 — bioinformatics — Posted on 2024-10-23
1572 Avifauna composition in Rice plantations: effects of Harvesting Stage and Surrounding Vegetation. Insights from Weppa Farm, Agenebode.
Ibrahim, I.; Antonio, B.; Tongken, D. M.; Clement, B.; Bello, B. S.; Ugome, O.; Samuel, J. A.; Patrick, H.; Dike, C.
10.1101/2024.10.20.619302 — ecology — Posted on 2024-10-23
1575 Fucoidan-Copper Nanoparticles to Potentiate Synergistic Cancer Cell Cuproptosis and Immunotherapy
Chen, H.; Pang, X.-H.; Wang, Q.-H.; Chen, Z.; Zhuang, L.-l.; Luo, J.-y.; Zheng, Q.-x.; Zhong, R.-f.; Zhan, X.-m.; Yang, L.; Zhu, L.; Jiang, J.-G.
10.1101/2024.10.20.619277 — cancer biology — Posted on 2024-10-23
1576 Diphenyleneiodonium chloride inhibits MYCN-amplified neuroblastoma by targeting MYCN induced mitochondrial alterations
Epp, S.; Maher, S.; Adlina, A.; Marcone, S.; Egan, D.; Haapa-Paananen, S.; Fey, V.; Iljin, K.; Wynne, K.; Jensen, L. D.; Kolch, W.; Halasz, M.
10.1101/2024.10.20.619268 — cancer biology — Posted on 2024-10-23
1577 The protease interpain A of Prevotella intermedia promotes human OSCC cells proliferation and migration
Chang, S.-M.; Huang, I.-H.; Ciou, Y.-J.; Wang, W.-R.; Wu, N.-H.; Chuu, C.-P.; Hsiao, J.-R.; Chang, J. S.; Chang, J.-Y.; Chen, J.-W.
10.1101/2024.10.20.619282 — cancer biology — Posted on 2024-10-23
1578 All-trans retinoic acid-mediated ADAR1 degradation synergizes with PD-1 blockade to suppress pancreatic cancer
Li, C.-F.; Bai, L.-Y.; Wei, Y.; Lee, H.-H.; Yang, R.; Yao, J.; Wang, H.; Wang, Y.-N.; Chang, W.-C.; Shen, Y.-C.; Wang, S.-C.; Chou, C.-W.; Fu, J.; Ling, J.; Chu, Y.-Y.; Chiu, C.-F.; Wang, M.; Yu, D.; Chiao, P. J.; Liang, H.; Maitra, A.; Ying, H.; Hung, M.-C.
10.1101/2024.10.20.619300 — cancer biology — Posted on 2024-10-23
1581 Dissecting Breast Cancer Heterogeneity Through Transcriptomics Insights of Diverse Etiological Factors for Common Biomarker Discovery
Hossain, M. U.; Mehak, M. A.; Hasan, S. S.; Sakib, M. N.; Rahman, A. B. Z. N.; Bhattacharjee, A.; Chowdhury, Z. M.; Ahammad, I.; Sohag, M. M. H.; Das, K. C.; Salimullah, M.
10.1101/2024.10.20.619262 — bioinformatics — Posted on 2024-10-23
1584 Somatic Mutations in MCOLN3 in Aldosterone-Producing Adenomas cause Primary Aldosteronism.
van Rooyen, D.; Bandulik, S.; Coon, G.; Laukemper, M.; Kumar-Sinha, C.; Udager, A. M.; Lee, C.; Wachtel, H.; Cohen, D. L.; Luther, J. M.; Giordano, T.; Turcu, A.; Warth, R.; Rainey, W. E.; Rege, J.
10.1101/2024.10.20.619295 — genetics — Posted on 2024-10-23
1588 A comprehensive survey of RNA modifications in a human transcriptome
Mulroney, L.; Coscujuela-Tarrero, L.; Maragno, P.; Rubolino, C.; Maestri, S.; Furlan, M.; Marzi, M. J.; Fitzgerald, T. W.; Leonardi, T.; Pelizzola, M.; Birney, E.; Nicassio, F.
10.1101/2024.10.22.619587 — genomics — Posted on 2024-10-23
1589 Nested admixture during and after the Trans-Atlantic Slave Trade on the island of Sao Tome
Ciccarella, M.; Laurent, R.; Szpiech, Z. A.; Patin, E.; Dessarps-Freichey, F.; Utge, J.; Lemee, L.; Semo, A.; Rocha, J.; Verdu, P.
10.1101/2024.10.21.619344 — genetics — Posted on 2024-10-23
1590 The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity
Cerezo, M.; Sollis, E.; Ji, Y.; Lewis, E.; Abid, A.; Bircan, K. O.; Hall, P.; Hayhurst, J.; John, S.; Mosaku, A.; Ramachandran, S.; Foreman, A. L.; Ibrahim, A.; McLaughlin, J.; Pendlington, Z.; Stefancsik, R.; Lambert, S.; McMahon, A.; Morales, J.; Keane, T.; Inouye, M.; Parkinson, H.; Harris, L. W.
10.1101/2024.10.23.619767 — genetics — Posted on 2024-10-23
1595 Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis
Dong, J.; Chen, M.; van Weering, J. R. T.; Li, K. W.; Smit, A. B.; Toonen, R. F.; Verhage, M.
10.1101/2024.01.02.573873 — neuroscience — Posted on 2024-10-23
1597 Hemispheric difference of adaptation lifetime in human auditory cortex measured with MEG
Dar, A. H.; Haertwich, N.; Hajizadeh, A.; Brosch, M.; Koenig, R.; May, P. J. C.
10.1101/2024.04.16.588236 — neuroscience — Posted on 2024-10-23
1599 LIFERING, an E3 ligase ubiquitinates the acyl-CoA dehydrogenase-like protein IBR3, and coordinates cell proliferation and death upon DNA damage
Kallai, B.; Nemeth, E.; Pettko-Szandtner, A.; Ahmad, Z.; Nagy, F.; Bogre, L.; Magyar, Z.; Meszaros, T.; Horvath, B. M.
10.1101/2024.10.18.619078 — plant biology — Posted on 2024-10-23
1600 Cystobactamid off-target profiling reveals favorable safety, superoxide reduction, and SCARB1 inhibition in eukaryotes
Risch, T.; Hellwinkel, B.; Mostert, D.; Kany, A. M.; Solga, D.; Seedorf, T.; Heimann, D.; Hoppstädter, J.; Kohnhäuser, D.; Hilgers, J.-S.; Fries, F.; Deschner, F.; Brönstrup, M.; Kirschning, A.; Sieber, S. A.; Pietschmann, T.; Kiemer, A. K.; Herrmann, J.; Müller, R.
10.1101/2024.10.10.617689 — pharmacology and toxicology — Posted on 2024-10-23
1605 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.
10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-10-23
1608 Interface-aware molecular generative framework for protein-protein interaction modulators
Wang, J.; Mao, J.; Li, C.; Xiang, H.; Wang, X.; Wang, S.; Wang, Z.; Chen, Y.; Li, Y.; No, K. T.; Song, T.; Zeng, X.
10.1101/2023.10.10.557742 — bioinformatics — Posted on 2024-10-23
1609 Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes in vivo
Couderc, E.; Crist, A. B.; Daron, J.; Varet, H.; Van Hout, F. A. H.; Miesen, P.; Palatini, U.; Dabo, S.; Vial, T.; LAMBRECHTS, L.; Merkling, S.
10.1101/2024.07.01.601473 — immunology — Posted on 2024-10-23
1610 Adaptation of retinal discriminability to natural scenes
Ding, X.; Lee, D.; Melander, J. B.; Ganguli, S.; Baccus, S. A.
10.1101/2024.09.26.615305 — neuroscience — Posted on 2024-10-23
1612 Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes in vivo
Couderc, E.; Crist, A. B.; Daron, J.; Varet, H.; Van Hout, F. A. H.; Miesen, P.; Palatini, U.; Dabo, S.; Vial, T.; LAMBRECHTS, L.; Merkling, S.
10.1101/2024.07.01.601473 — immunology — Posted on 2024-10-23
1613 Optical characterization of molecular interaction strength in protein condensates
Beck, T.; van der Linden, L.-M.; Borcherds, W. M.; Kim, K.; Schluessler, R.; Mueller, P.; Franzmann, T.; Moeckel, C.; Goswami, R.; Leaver, M.; Mittag, T.; Alberti, S.; Guck, J.
10.1101/2024.03.19.585750 — biophysics — Posted on 2024-10-23
1614 Camera Paths, Modeling, and Image Processing Tools for ArtiaX
Ermel, U. H.; Moser, D.; Roth, P.; Arctaedius, G.; Wehrheim, M. H.; Scheffer, M. P.; Frangakis, A. S.
10.1101/2024.09.23.614454 — bioinformatics — Posted on 2024-10-23
1615 Why the brown ghost chirps at night
Oboti, L.; Pedraja, F.; Ritter, M.; Lohse, M.; Klette, L.; Krahe, R.
10.1101/2022.12.29.522225 — animal behavior and cognition — Posted on 2024-10-23
1617 Multi-color fluorescence live-cell imaging in Dictyostelium discoideum
Hashimura, H.; Kuwana, S.; Nakagawa, H.; Abe, K.; Adachi, T.; Sugita, T.; Fujishiro, S.; Honda, G.; Sawai, S.
10.1101/2024.10.22.619593 — cell biology — Posted on 2024-10-23
1620 NIPBL and STAG1 enable loop extrusion by providing differential DNA-cohesin affinity
van Wee, R.; Asor, R.; Li, Y.; Drechsel, D.; Popova, M.; Litos, G.; Davidson, I.; Peters, J.-M.; Kukura, P.
10.1101/2024.10.22.619583 — biophysics — Posted on 2024-10-22
1621 DNA-Dependent Protein Kinase Inhibitors PI-103 and Samotolisib Augment CRISPR/Cas9 Knockin Efficiency in Human T Cells
Dzafo, E.; Hafezi, M.; Giordano Attianese, G. M. P.; Reichenbach, P.; Grillet, S.; Scholten, K.; Coukos, G.; Irving, M.; Gentner, B.
10.1101/2024.10.18.618985 — bioengineering — Posted on 2024-10-22
1622 Age-Dependent Maturation and Rejuvenation of the Neural 3D Chromatin Interactome in Enriched Environments
Gancedo-Verdejo, J.; Urdinguio, R. G.; Tejedor, J. R.; Perez, R. F.; Penarroya, A.; Santamarina-Ojeda, P.; Roberti, A.; Kefauver, J. M.; Alvarez-Diaz, C.; Rodriguez-Santamaria, M.; Trejo, J. L.; Tomas-Daza, L.; Rovirosa, L.; Javierre, B. M.; Fernandez, A. F.; Fraga, M. F.
10.1101/2024.10.22.619383 — genomics — Posted on 2024-10-23
1623 Ancient DNA analyses of two Early Chalcolithic Individuals from the West Mound
Dogu, A.; Kaptan, D.; Yuncu, E.; Gurun, K.; Vural, K. B.; Chylenski, M.; Byrnes, J.; Gotherstrom, A.; Ozer, F.; Somel, M.
10.1101/2024.10.22.619570 — genetics — Posted on 2024-10-23
1626 Deletion of Zyxin Reduces Endothelial Inflammation and Mitigates Atherosclerosis
Huang, H.; Feng, Y.; Gao, Z.; Li, L.; Li, Y.; Li, Z.; Liao, B.; Liu, L.; liu, Z.; YongMei, N.; Tang, Y.; Wang, Y.; Weng, H.; Xie, Y.; Yang, T.; FengXu, Y.
10.1101/2024.10.21.619550 — cell biology — Posted on 2024-10-22
1627 Rejuvenating aged osteoprogenitors for bone repair
Reeves, J.; Tournier, P.; Becquart, P.; Carton, R.; Tang, Y.; Vigilante, A.; Fang, D.; Habib, S. J.
10.1101/2024.10.22.619605 — cell biology — Posted on 2024-10-22
1628 SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification
Padovani, F.; Cavka, I.; Neves, A. R. R.; Lopez, C. P.; Al-Refaie, N.; Bolcato, L.; Chatzitheodoridou, D.; Chadha, Y.; Su, X. A.; Lengefeld, J.; Cabianca, D. S.; Köhler, S.; Schmoller, K. M.
10.1101/2024.10.22.619610 — cell biology — Posted on 2024-10-23
1629 Human Satellite 3 DNA encodes megabase-scale transcription factor binding platforms
Franklin, J. M.; Dubocanin, D.; Chittenden, C.; Barillas, A. G.; Lee, R. J.; Ghosh, R. P.; Gerton, J. L.; Guan, K.-L.; Altemose, N.
10.1101/2024.10.22.616524 — cell biology — Posted on 2024-10-23
1632 Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
Salazar, M. P. R.; Kolanukuduru, S.; Ramirez, V.; Lyu, B.; Sejourne, G.; Sesaki, H.; Yu, G.; Eroglu, C.
10.1101/2024.10.22.619706 — cell biology — Posted on 2024-10-23
1636 Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
Yulo, P. R.; Desprat, N.; Gerth, M. L.; Ritzl-Rinkenberger, B.; Farr, A. D.; Liu, Y.; Zhang, X.-X.; Miller, M.; Cava, F.; Rainey, P. B.; Hendrickson, H. L.
10.1101/263681 — microbiology — Posted on 2024-10-22
1639 The gene expression signature of electrical stimulation in the human brain
Chatterjee, S.; Vanrobaeys, Y.; Gleason, A. I.; Park, B. J.; Heiney, S. A.; Rhone, A. E.; Nourski, K. V.; Langmack, L.; Basu, B.; Mukherjee, U.; Kovach, C. K.; Kocsis, Z.; Kikuchi, Y.; Ayala, Y. A.; Petkov, C. I.; Hefti, M. M.; Bahl, E.; Michaelson, J. J.; Kawasaki, H.; Oya, H.; Howard, M. A.; Nickl-Jockschat, T.; Lin, L.-C.; Abel, T.
10.1101/2023.09.21.558812 — neuroscience — Posted on 2024-10-22
1641 Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
Chedid, J.; Li, Y.; Labrador-Garrido, A.; Abu-Bonsrah, D.; Pavan, C.; Fraser, T.; Zhong, M.; Johnston, J. A.; Thompson, L. H.; Kirik, D.; Parish, C.; Halliday, G.; Sue, C.; Wali, G.; Dzamko, N.
10.1101/2024.10.07.617117 — neuroscience — Posted on 2024-10-22
1645 Sugarcane yellow leaf virus impairs the transcriptomic defense responses of sugarcane to its new aphid vector Melanaphis sorghi
Pimenta, R. J. G.; Aono, A. H.; Sforca, D. A.; Melloni, M. N. G.; Goncalves, M. C.; Pinto, L. R.; de Souza, A. P.
10.1101/2024.10.17.618922 — plant biology — Posted on 2024-10-22
1646 Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient
Truong Le, T.; Yi-Te Wang, D.; Chen, K.-C.; Yan, S. R.-G.; Chu, P.-Y.; Tan, T. Z.; Chiu, Y.-C.; Sheu, J.-Y.; Huang, C.-H.; Ye, J.; Tai, Y.-T.; Juan, H.-F.; Tsai, F.-C.; Lin, W.-C.; Wei, L.-H.; Huang, R. Y.-J.
10.1101/2024.10.19.619181 — cancer biology — Posted on 2024-10-22
1647 Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing
Huang, Y.; Wu, G.; Bi, G.; Cheng, L.; Liang, J.; Li, M.; Zhang, H.; Shan, G.; Hu, Z.; Chen, Z.; Lin, Z.; Jiang, W.; Wang, Q.; Xi, J.; Yin, S.; Zhan, C.
10.1101/2024.02.18.580893 — cancer biology — Posted on 2024-10-22
1648 CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics data
Yang, B.; Meng, T.; Wang, X.; Li, J.; Zhao, S.; Wang, Y.; Yi, S.; Zhou, Y.; Zhang, Y.; Li, L.; Guo, L.
10.1101/2024.01.21.576587 — bioinformatics — Posted on 2024-10-22
1649 Reinforcement learning guides single-cell sequencing in decoding lineage and cell fate decisions
Fu, Z.; Wang, S.; Sun, K.; Xu, B.; Ye, X.; Wen, Z.; Shen, M.; Chen, M.; Chen, F.; Xu, Y.; Deng, Y.; Wang, J.; Chen, S.
10.1101/2024.07.04.602019 — bioinformatics — Posted on 2024-10-22
1653 Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants
Tiwari, M.; Gas-Pascual, E.; Goyal, M.; Popov, M.; Matsumoto, K.; Grafe, M.; Graf, R.; Haltiwanger, R. S.; Olszewski, N. E.; Orlando, R.; Samuelson, J.; West, C. M.
10.1101/2024.10.15.618526 — cell biology — Posted on 2024-10-22
1655 Novel bacteriophages targeting wheat phyllosphere bacteria carry DNA modifications and single-strand breaks
Dougherty, P. E.; Pedersen, M. S.; Forero-Junco, L. M.; Carstens, A. B.; Raaijmakers, J. M.; Riber, L.; Hansen, L. H.
10.1101/2024.10.22.619576 — microbiology — Posted on 2024-10-22
1659 Ketosis Elevates Antioxidants and Enhances Neural Function Through Improved Bioenergetics: A 1H MR Spectroscopy Study
van Nieuwenhuizen, H.; Antal, B. B.; Hone-Blanchet, A.; Lithen, A.; McMahon, L.; Nikolaidou, S.; Kuang, Z.; Clarke, K.; Jenkins, B. G.; Rothman, D. L.; Mujica-Parodi, L. R.; Ratai, E.-M.
10.1101/2024.10.22.619722 — neuroscience — Posted on 2024-10-22
1661 Polyphenol rewiring of the microbiome reduces methane emissions
McGivern, B. B.; Ellenbogen, J. B.; Hoyt, D. W.; Bouranis, J. A.; Stemple, B. P.; Daly, R. A.; Bosman, S. H.; Sullivan, M. B.; Hagerman, A. E.; Chanton, J. P.; Tfaily, M. M.; Wrighton, K. C.
10.1101/2024.10.22.619724 — microbiology — Posted on 2024-10-22
1662 Fish are poor sentinels for surveillance of riverine AMR
Tskhay, F.; Köbsch, C.; Elena, A. X.; Bengtsson-Palme, J.; Berendonk, T. U.; Klümper, U.
10.1101/2024.10.22.619632 — microbiology — Posted on 2024-10-22
1663 Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria
Kapoor, Y.; Khurana, H.; Chakraborty, A.; Dutta, D.; Priya, A.; Singh, A.; Kamat, S.; Dhar, N.; Pucadyil, T.; Nandicoori, V.
10.1101/2024.10.22.619650 — microbiology — Posted on 2024-10-22
1664 Interferon-mediated NK cell activation is associated with limited neutralization breadth during SARS-CoV-2 infection
de los Rios Kobara, I.; Jayewickreme, R.; Lee, M. J.; Wilk, A. J.; Stanford COVID-19 Biobank, ; Blomkalns, A. L.; Nadeau, K. C.; Yang, S.; Rogers, A. J.; Blish, C. A.
10.1101/2024.10.22.619639 — immunology — Posted on 2024-10-22
1665 Proper reference selection and re-referencing to mitigate bias in single pulse electrical stimulation data
Huang, H.; Adkinson, J. A.; Jensen, M. A.; Hasen, M.; Danstrom, I. A.; Bijanki, K. R.; Gregg, N. M.; Miller, K. J.; Sheth, S. A.; Hermes, D.; Bartoli, E.
10.1101/2024.10.21.619449 — neuroscience — Posted on 2024-10-22
1666 5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA
Pomrenze, M. B.; Vaillancourt, S.; Salgado, J. S.; Raymond, K. B.; Llorach, P.; Touponse, G. C.; Pinto, D. F. C.; Rastegar, Z.; Casey, A. B.; Eshel, N.; Malenka, R. C.; Heifets, B. D.
10.1101/2024.10.20.619256 — neuroscience — Posted on 2024-10-22
1667 The neural correlates of shared and individual experience
Coppola, P.; Owen, A. M.; Menon, D.; Naci, L.; Stamatakis, E. A.
10.1101/2024.10.20.619030 — neuroscience — Posted on 2024-10-22
1669 A 128-channel receive array with enhanced SNR performance for 10.5 tesla brain imaging
Lagore, R. L.; Sadeghi-Tarakameh, A.; Grant, A.; Waks, M.; Auerbach, E.; Jungst, S.; DelaBarre, L.; Moeller, S.; Eryaman, Y.; Lattanzi, R.; Giannakopoulos, I.; Vizioli, L.; Yacoub, E.; Schmidt, S.; Metzger, G. J.; Wu, X.; Adriany, G.; Ugurbil, K.
10.1101/2024.10.20.619294 — neuroscience — Posted on 2024-10-22
1670 Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N.; Brynildsen, J. K.; Goralski, T. M.; Kurgat, K.; Meyerdirk, L.; Breton, L.; DeWeerd, D.; Brasseur, L.; Turner, L.; Becker, K.; Gallik, K. L.; Bassett, D. S.; Henderson, M. X.
10.1101/2024.10.22.619411 — neuroscience — Posted on 2024-10-22
1672 Oxytocin neurons signal state-dependent transitions to thermogenesis and behavioral arousal in social and non-social settings.
Vandendoren, M.; Rogers, J. F.; Landen, J. G.; Killmer, S.; Alimiri, B.; Pohlman, C.; Tattersall, G. J.; Bedford, N. L.; Nelson, A. C.
10.1101/2024.10.22.619715 — neuroscience — Posted on 2024-10-22
1673 Cannabidiol reverses microglia activation and loss of parvalbumin interneurons and perineuronal nets in a mouse model of schizophrenia
Rodrigues da Silva, N.; Gobbo, D.; Gomes, F.; Scheller, A.; Kirchhoff, F.; Del Bel, E.; Silveira Guimaraes, F.
10.1101/2024.10.21.619352 — neuroscience — Posted on 2024-10-22
1674 Hierarchical emergence of opponent coding in auditory belt cortex
Johnson, J. S.; Niwa, M.; O'Connor, K. N.; Malone, B. J.; Sutter, M. L.
10.1101/2024.10.22.619743 — neuroscience — Posted on 2024-10-22
1676 Arc mediates intercellular tau transmission via extracellular vesicles
Tyagi, M.; Chadha, R.; de Hoog, E.; Sullivan, K. R.; Walker, A. C.; Northrop, A.; Fabian, B.; Fuxreiter, M.; Hyman, B. T.; Shepherd, J. D.
10.1101/2024.10.22.619703 — neuroscience — Posted on 2024-10-22
1677 Parkinsonism disrupts neuronal modulation in the pre-supplementary motor area during movement preparation
Hendrix, C. M.; Baker, H. E.; Yu, Y.; Schneck, D. D.; Wang, J.; Johnson, L. A.; Vitek, J. L.
10.1101/2024.10.22.619634 — neuroscience — Posted on 2024-10-22
1678 An end-to-end model of active electrosensation
Turcu, D.; Zadina, A. N.; Abbott, L.; Sawtell, N. B.
10.1101/2024.10.22.619741 — neuroscience — Posted on 2024-10-22
1679 Human short association fibers are thinner and less myelinated than long fibers
Ruthig, P.; Edler v.d. Planitz, D.; Morozova, M.; Reimann, K.; Jäger, C.; Reinert, T.; Mohammadi, S.; Weiskopf, N.; Kirilina, E.; Morawski, M.
10.1101/2024.10.21.619354 — neuroscience — Posted on 2024-10-22
1684 The transfer of antibiotic resistance genes between evolutionary distant bacteria
Parras-Molto, M.; Lund, D.; Ebmeyer, S.; Larsson, D. G. J.; Johnning, A.; Kristiansson, E.
10.1101/2024.10.22.619579 — microbiology — Posted on 2024-10-22
1685 Environmental stability of HPAIV H5N1 in raw milk, wastewater and on surfaces
Kaiser, F.; Cardenas, S.; Yinda, K. C.; Mukesh, R.; Ochwoto, M.; Gallogly, S.; Wickenhagen, A.; Bibby, K.; de Wit, E.; Morris, D.; Lloyd-Smith, J. O.; Munster, V.
10.1101/2024.10.22.619662 — microbiology — Posted on 2024-10-22
1686 A rational approach for the targeted discovery and characterisation of microbiome-derived therapeutics
Krause, L.; Boyd, J.; Vivian, C.; Krueger, A.; Jimenez Loayza, J.; Ljungberg, J.; Zhou, J.; Rabellino, A.; Nyeverecz, B.; Nissen, M.; Tousignant, K.; Bongers, M.; Cooper, M. M.; Parks, D. H.; Alsheikh, A.; Vera-Wolf, P.; Sullivan, M.; Newell, R.; Masterman, K.-A.; Evans, P.; Fang, L.; MacDonald, S.; Chuvochina, M.; Bessette, D.; Zimmermann, K.; Pribyl, A.; Chipperfield, H.; Caban, S.; McCarthy, H.; Soh, J.; Reid, L.; Frazer, I. H.; Angel, N.; Kenna, T.; Wood, D. L. A.; Wills, B.; Begun, J.; Keely, S.; Munro, T.; Tyson, G.; Hugenholtz, P.; O Cuiv, P.
10.1101/2024.10.22.619608 — microbiology — Posted on 2024-10-22
1688 Single-Cell Transcriptomics Unveils Skin Cell Specific Antifungal Immune Responses and IL-1Ra- IL-1R Immune Evasion Strategies of Emerging Fungal Pathogen Candida auris
Balakumar, A.; Das, D.; Datta, A.; Mishra, A.; Bryak, G.; Ganesh, S. M.; Netea, M.; Kumar, V.; Lionakis, M.; Arora, D.; Thimmapuram, J.; Thangamani, S.
10.1101/2024.10.22.619653 — microbiology — Posted on 2024-10-22
1689 Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology
Boucher, M.; Banerjee, S.; Joshi, M.; Wei, A.; Huang, M.; Lei, S.; Ciranni, M.; Condon, A.; Langen, A.; Goddard, T.; Caradonna, I.; Goranov, A.; Homer, C.; Mortensen, Y.; Petnic, S.; Reilly, M.; Xiong, Y.; Susa, K.; Pastore, V. P.; Zaro, B.; Madhani, H.
10.1101/2024.10.22.619677 — microbiology — Posted on 2024-10-22
1693 Visual objects refine head direction coding
Siegenthaler, D.; Denny, H.; Skromne Carrasco, S.; Mayer, J. L.; Peyrache, A.; Trenholm, S.; Mace, E.
10.1101/2024.10.21.619417 — neuroscience — Posted on 2024-10-22
1694 Spatial memory in Alzheimer's disease 5XFAD mice is enhanced by XPO1 inhibitor KPT-330
Wong, S. Q.; Ouellette, A.; McNamara, A.; Tam, R.; Alexandrov, A.; Nawrocik-Madrid, A.; Sanchez, J. J.; Ginsburg, B. C.; Andrade, A. A.; Lapierre, L. R.
10.1101/2024.10.21.619493 — neuroscience — Posted on 2024-10-22
1697 Revealing Acute Consequences of Rapid Protein Elimination at Individual Synapses using Auxin-Inducible Degron 2 Technology
Elbaum, L.; Yuan, W.; Seiler, J. P.- H.; Blom, N.; Chan, Y.-C.; Baig, A. H.; Brose, N.; Rumpel, S.; Ziv, N. E.
10.1101/2024.10.20.619267 — neuroscience — Posted on 2024-10-22
1701 Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development
Wang, Q.; Li, H.; Mao, Y.; Garg, A.; Park, E. S.; Wu, Y.; Chow, A.; Peregrin, J.; Zhang, X.
10.1101/2024.10.20.619055 — developmental biology — Posted on 2024-10-22
1702 A transcriptionally active lipid vesicle encloses theinjected Chimalliviridae genome in early infection
Armbruster, E.; Rani, P.; Lee, J.; Klusch, N.; Hutchings, J.; Hoffman, L. Y.; Buschkaemper, H.; Enustun, E.; Adler, B.; Inlow, K.; VanderWal, A.; Hoffman, M. Y.; Daksh, D.; Aindow, A.; Deep, A.; Rodriguez, Z.; Morgan, C. J.; Ghassemian, M.; Laughlin, T. G.; Charles, E.; Cress, B. F.; Savage, D. F.; Doudna, J.; Pogliano, K.; Corbett, K. D.; Villa, E.; Pogliano, J.
10.1101/2023.09.20.558163 — cell biology — Posted on 2024-10-22
1705 Impairment of Neuronal Activity in the Dorsolateral Prefrontal Cortex Occurs Early in Parkinsonism
Hjelle, N.; Mohanty, B.; Hubbard, T.; Johnson, M.; Wang, J.; Johnson, L. A.; Vitek, J. L.
10.1101/2024.10.22.619684 — neuroscience — Posted on 2024-10-22
1706 Robust coexistence in ecological competitive communities
Lechon-Alonso, P.; Kundu, S.; Lemos-Costa, P.; Capitan, J. A.; Allesina, S.
10.1101/2024.07.10.602979 — ecology — Posted on 2024-10-22
1707 Oxygen level alters energy metabolism in bovine preimplantation embryos
Boskovic, N.; Ivask, M.; Yazgeldi Gunaydin, G.; Yasar, B.; Katayama, S.; Salumets, A.; Org, T.; Kurg, A.; Lundin, K.; Tuuri, T.; Daub, C. O.; Kere, J.
10.1101/2024.10.20.619258 — developmental biology — Posted on 2024-10-22
1708 Local control of cellular proliferation underlies neuromast regeneration in zebrafish
Lavalle, N. G.; Miranda, J.; Cura Costa, E.; Borges, A.; Viader-Llargues, O.; Lopez Schier, H.; Chara, O.
10.1101/2024.10.22.619208 — developmental biology — Posted on 2024-10-22
1712 Universal high-throughput image quantification of subcellular structure dynamics and spatial distributions within cells
Grinstaff, M.; Martin, A.; Zhang, S.; Williamson, A.; Tingley, B.; Pickus, M.; Zurakowski, D.; Nia, H.; Shirihai, O. S.; Han, X. S.
10.1101/2024.08.18.608451 — cell biology — Posted on 2024-10-22
1717 Opto2P-FCM: A MEMS based miniature two-photon microscope with two-photon patterned optogenetic stimulation
Futia, G. L.; Zohrabi, M.; McCullough, C.; Teel, A.; Simoes de Souza, F.; Oroke, R.; Miscles, E. J.; Ozbay, B. N.; Kilborn, K.; Bright, V. M.; Restrepo, D.; Gopinath, J. T.; Gibson, E. A.
10.1101/2024.10.21.619528 — neuroscience — Posted on 2024-10-22
1720 Control of spatiotemporal activation of organ-specific fibers in the vagus nerve by intermittent interferential current stimulation
Rossetti, N.; Song, W.; Schnepel, P.; Jayaprakash, N.; Koutsouras, D.; Fichman, M.; Wong, J.; Levy, T.; Elgohary, M.; Qanud, K.; Giannotti, A.; Barbe, M.; Chen, F. L.; Langereis, G.; Datta-Chaudhuri, T.; Mihajlovic, V.; Zanos, S.
10.1101/2024.10.22.619669 — neuroscience — Posted on 2024-10-22
1724 Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core
Lan, Z.; Chen, Y.; Rushmore, J.; Zekelman, L.; Makris, N.; Rathi, Y.; Golby, A. J.; Zhang, F.; O'Donnell, L. J.
10.1101/2024.10.19.619237 — neuroscience — Posted on 2024-10-22
1725 Dysregulated balance of D- and L-amino acids modulating glutamatergic neurotransmission in severe spinal muscular atrophy.
Hassan, A.; di Vito, R.; Nuzzo, T.; Vidali, M.; Carlini, M. J.; Yadav, S.; Yang, H.; D'Amico, A.; Kolici, X.; Valsecchi, V.; Panicucci, C.; Pignataro, G.; Bruno, C.; Bertini, E.; Errico, F.; Pellizzoni, L.; Usiello, A.
10.1101/2024.10.22.619645 — neuroscience — Posted on 2024-10-22
1726 Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff disease
Tsourmas, K. I.; Butler, C. A.; Kwang, N. E.; Sloane, Z. R.; Dykman, K. J. G.; Maloof, G. O.; Prekopa, C. A.; Krattli, R. P.; El-Khatib, S. M.; Swarup, V.; Acharya, M. M.; Hohsfield, L. A.; Green, K. N.
10.1101/2024.10.21.619538 — neuroscience — Posted on 2024-10-22
1727 Control of innate olfactory valence by segregated cortical amygdala circuits
Howe, J. R.; Chan, C.-L.; Lee, D.; Blanquart, M.; Romero, H.; Zadina, A. N.; Lemieux, M. E.; Desplats, P. A.; Tye, K. M.; Root, C. M.
10.1101/2024.06.26.600895 — neuroscience — Posted on 2024-10-22
1729 A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV
Ostermann, P. N.; Wu, Y.; Bowler, S. A.; Siddiqui, M. A.; Herrera, A.; Sidharta, M.; Ramnarine, K.; Martinez-Meza, S.; St. Bernard, L. A.; Nixon, D. F.; Jones, R. B.; Yamashita, M.; Ndhlovu, L. C.; Zhou, T.; Evering, T. H.
10.1101/2024.10.22.619617 — neuroscience — Posted on 2024-10-22
1730 Longitudinal neuromelanin changes in prodromal and early Parkinson's disease in humans and rat model
Perot, J.-B.; Ruze, A.; Gaurav, R.; Rebbah, S.; Cadin, C.; Le Troter, A.; Soustelle, L.; Mouton, L.; Valabregue, R.; Parent, A.; Mangone, G.; Lejeune, F.-X.; Arnulf, I.; Corvol, J.-C.; Vidailhet, M.; Santin, M. D.; Vila, M.; Lehericy, S.
10.1101/2024.10.22.619619 — neuroscience — Posted on 2024-10-22
1732 Photosynthetic demands on translational machinery drive retention of redundant tRNA metabolism in plant organelles
DeTar, R. A.; Chustecki, J.; Martinez-Hottovy, A.; Cerrioti, L. F.; Broz, A. K.; Sanchez-Puerta, M. V.; Elowsky, C.; Christensen, A. C.; Sloan, D. B.
10.1101/2023.08.01.551541 — plant biology — Posted on 2024-10-22
1742 Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism
Tsai, C.-E.; Wang, F.-Q.; Yang, C.-W.; Yang, L.-L.; Nguyen, T. V. P.; Chen, Y.-C.; Chen, P.-Y.; Hwang, I.-S.; Ting, S.-Y.
10.1101/2024.09.13.612980 — microbiology — Posted on 2024-10-22
1743 Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons
Belfort, B. D.; Jia, J. D.; Garza, A. R.; Insalaco, A. M.; McGinnis, J. P.; Pekarek, B. T.; Ortiz, J.; Tepe, B.; Chen, H.; aSCENT-PD Investigators, ; Liu, Z.; Arenkiel, B. R.
10.1101/2024.09.26.615247 — neuroscience — Posted on 2024-10-22
1744 Chemically induced senescence prompts functional changes in human microglia-like cells
Armanville, S.; Tocco, C.; Haj Mohamad, Z.; Clarke, D.; Robitaille, R.; Drouin-Ouellet, J.
10.1101/2024.02.27.582168 — neuroscience — Posted on 2024-10-22
1746 The maternal vGluT2 and embryonic mGluR3 signaling relay system controls offspring wing dimorphism in pea aphid
Yuan, Y.; Wang, Y.; Ye, W.; Xie, L.; Yuan, E.; Guo, H.; Wang, S.; Dong, F.; Zhu-Salzman, K.; Ge, F.; Sun, Y.
10.1101/2024.05.22.595290 — zoology — Posted on 2024-10-22
1747 Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects
Ruyle, B.; Masud, S.; Kesaraju, R.; Tahirkheli, M.; Modh, J.; Lopera, S. A.; Lintz, T.; Higginbotham, J. A.; Massaly, N.; Moron, J. A.
10.1101/2024.09.16.613257 — physiology — Posted on 2024-10-22
1748 Controlling interfacial protein adsorption, desorption and aggregation in biomolecular condensates
Visser, B.; van Haren, M.; Lipinski, W.; van Leijenhorst-Groener, K.; Claessens, M.; Queiros, M.; Ramos, C.; Spruijt, E.
10.1101/2024.10.20.619145 — biophysics — Posted on 2024-10-22
1750 CNValidatron, automated validation of CNV calls using computer vision
Montalbano, S.; Walters, B.; Jonsson, G.; Gaadin, J.; Werge, T.; Stefansson, H.; Stefansson, K.; Ingason, A.
10.1101/2024.09.09.612035 — bioinformatics — Posted on 2024-10-22
1754 A probabilistic view of forbidden links: their prevalence and their consequences for the robustness of plant-hummingbird communities
Duchenne, F.; Barreto, E.; Guevara, E. A.; Beck, H.; Bello, C.; Bobato, R.; Bolla, D.; Brenes, E.; Büttner, N.; Caron, A. P.; Elizondo, N.; Restrepo-Gonzalez, A.; Castro, J. A.; Kaehler, M.; Machado-de-Souza, T.; Machnicki-Reis, M.; Marcayata-Fajardo, A. S.; de Menezes, C. G.; Nieto, A.; de Oliveira, R.; de Oliveira, R. A. C.; Richter, F.; Rojas, B. G.; Romanowski, L. L.; de Souza, W. L.; Veluza, D. S.; Weinstein, B.; Wüest, R.; Zanata, T. B.; Zuniga, K.; Maglianesi, M. A.; Santander, T.; Varassin, I. G.; Graham, C. H.
10.1101/2024.07.04.602032 — ecology — Posted on 2024-10-22
1759 Data Science in Olfaction
agarwal, v. K.; Harvey, J. S.; Rinberg, D.; Dhar, V.
10.1101/2024.10.19.619239 — neuroscience — Posted on 2024-10-22
1762 Investigating working memory updating processes of the human subcortex using 7T MRI
Trutti, A. C.; Sjoerds, Z.; Boag, R. J.; Walstra, S. L.; Miletic, S.; Isherwood, S. J.; Bazin, P.-L.; Hommel, B.; Habli, S.; Tse, D.; Haberg, A. K.; Forstmann, B. U.
10.1101/2024.03.14.584970 — neuroscience — Posted on 2024-10-22
1763 KRAS G12 mutant alleles differentially control glutamine metabolism via FOXO1
Ber, S.; Yang, M.; Sciacovelli, M.; Samarajiwa, S.; Patel, K.; Nikitopoulou, E.; Howitt, A.; Cook, S. J.; Venkitaraman, A. R.; Frezza, C.; Esposito, A.
10.1101/2024.10.19.618135 — cancer biology — Posted on 2024-10-22
1764 Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient
Truong Le, T.; Yi-Te Wan, D.; Chen, K.-C.; Yan, S. R.-G.; Chu, P.-Y.; Tan, T. Z.; Chiu, Y.-C.; Sheu, J.-Y.; Huang, C.-H.; Ye, J.; Tai, Y.-T.; Juan, H.-F.; Tsai, F.-C.; Lin, W.-C.; Wei, L.-H.; Huang, R. Y.-J.
10.1101/2024.10.19.619181 — cancer biology — Posted on 2024-10-22
1765 Modeling Glioma Intratumoral Heterogeneity with Primary Human Neural Stem and Progenitor Cells
Gao, D.; Liu, D. D.; Eastman, A. E.; Womack, N. L.; Ohene-Gambill, B. F.; Baez, M.; Weissman, I. L.
10.1101/2024.10.20.619254 — cancer biology — Posted on 2024-10-22
1767 PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins
Horne, C.; Dite, T. A.; Young, S. N.; Mather, L. J.; Dagley, L. F.; Johnson, J. L.; Yaron-Barir, T. M.; Huntsman, E. M.; Daly, L. A.; Byrne, D. P. A.; Cadell, A. L.; Ng, B. H.; Yousef, J.; Multari, D. H.; Shen, L.; McAloon, L. M.; Manning, G.; Febbraio, M. A.; Means, A. R.; Cantley, L. C.; Tanzer, M. C.; Croucher, D. R.; Eyers, C. E.; Eyers, P. A.; Scott, J. W.; Murphy, J. M.
10.1101/2024.10.20.619163 — biochemistry — Posted on 2024-10-22
1768 Ten-Fold Expansion MALDI Mass Spectrometry Imaging of Tissues and Cells at 500 nm Resolution
Xie, C.; Wang, J.; Diao, X.; Guo, L.; Lam, T. K.-Y.; Li, R.; Chen, Y.; Zhang, Y.; Wang, X.; Fang, J.; Cai, Z.
10.1101/2024.10.20.619316 — biochemistry — Posted on 2024-10-22
1769 Mosaic of Somatic Mutations in the Ancient and Still-Living Aspen Clone, Pando
Pineau, R.; Mock, K. E.; Morris, J. L.; Kraklow, V.; Brunelle, A.; Pageot, A.; Ratcliff, W. C.; Gompert, Z.
10.1101/2024.10.19.619233 — evolutionary biology — Posted on 2024-10-22
1772 Connectomic Organization of the Suprachiasmatic Nucleus
Liu, J.; Yu, J.; Shen, L.; Chen, X.; Ma, L.; Zhai, H.; Li, L.; Zhang, L.; Wang, L.; Yuan, J.; Chen, B.; Hong, B.; Liu, J.; Lv, Y.; Cai, Y.; Zhang, Y.; Chang, S.; Guo, J.; Chen, H.; Liu, M.; Wang, Z.; Xin, T.; Zhou, F.; Zhao, X.; Zhang, D.; Xie, Q.; Ma, H.; Xu, Y.; Cheng, H.; Han, H.
10.1101/2024.10.20.619252 — neuroscience — Posted on 2024-10-22
1773 Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal neurons and extends lifespan in an in vivo Drosophila tauopathy model
Paonessa, F.; Bizzini, B.; Campbell, T.; Solanki, R.; Butler, R.; Smith, J.; Davidson, C.; Larrieu, D.; Brand, A.; Livesey, F.
10.1101/2024.10.19.619211 — neuroscience — Posted on 2024-10-22
1777 Understanding the development of enzalutamide resistance based on a functional single-cell approach
Xue, C.; Ko, H.-K.; Shi, K.; Pittsenbarger, J.; Dao, L. V.; Shi, K.; Libmann, M.; Geng, H.; Qian, D. Z.
10.1101/2024.10.20.619319 — cancer biology — Posted on 2024-10-22
1779 Layer-specific dynamics of local field potentials in monkey V1 during electrical stimulation
Lee, S.; Zhao, Z.; Alekseichuk, I.; Shirinpour, S.; Linn, G.; Schroeder, C. E.; Falchier, A. Y.; Opitz, A.
10.1101/2024.10.19.619242 — biophysics — Posted on 2024-10-22
1780 Scale-free flocking and giant fluctuations in epithelial active solids
Shen, Y.; O'Byrne, J.; Schoenit, A.; Maitra, A.; Mege, R.-M.; Voituriez, R.; Ladoux, B.
10.1101/2024.10.18.619133 — biophysics — Posted on 2024-10-22
1781 Correlating Disordered Activation Domain Ensembles with Gene Expression Levels
Flores, E.; Camacho, A.; Cuevas-Zepeda, E.; McCoy, M. B.; Yu, F.; Staller, M. V.; Sukenik, S.
10.1101/2024.10.19.619222 — biophysics — Posted on 2024-10-22
1785 Multi-Channel Funnel Adapted Sensing Tube (MFAST) for the Simple and Duplex Detection of Parasites
Peng, R.; Yuqing, H.; Wiggins, T. J.; Bahadori, N.; Dollery, S. J.; Waitkus, J.; Rogers, J.; Chen, Y.; Tobin, G. J.; Du, K.
10.1101/2024.10.19.619249 — bioengineering — Posted on 2024-10-22
1788 Genomic diversity and underlying metabolic variations of the human gut microbiome between populations at single nucleotide resolution
Dong, Q.; Ma, B.; Zhou, X.; Huang, P.; Gao, M.; Yang, S.; Jiao, Y.; Zhou, Y.; Shi, Z.; Deng, Q.; Hua, D.; Wang, X.; Liu, L.; Zhang, C.; Zhang, C.; Kong, M.; He, C.; Wu, T.; Zou, H.; Shi, J.; Sheng, Y.; Wang, Y.; Tang, L.; Hu, S.; Zhong, H.; Sun, W.; Chen, W.; Zhai, Q.; Kong, X.; Zheng, Y.; Chen, L.
10.1101/2024.10.19.618999 — genomics — Posted on 2024-10-22
1792 Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells
Alvarez-Arguedas, S.; Mazhar, K.; Wangzhou, A.; Sankaranarayanan, I.; Gaona, G.; Lafin, J. T.; Mitchell, R. B.; Price, T. J.; Shiloh, M. U.
10.1101/2024.10.19.619143 — immunology — Posted on 2024-10-22
1793 Inducible, but not constitutive, pancreatic REG/Reg isoforms are regulated by intestinal microbiota and pancreatic diseases
Zhou, Y.; Komnick, M. R.; Sepulveda, F.; Liu, G.; Nieves-Ortiz, E.; Meador, K.; Ndatabaye, O.; Fatkhullina, A.; Wu-Woods, N.; Naydenkov, P. M.; Kent, J.; Christiansen, N.; Madariaga, M. L.; Witkowski, P.; Ismagilov, R. F.; Esterhazy, D.
10.1101/2024.10.18.619139 — immunology — Posted on 2024-10-22
1796 Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core
Lan, Z.; Chen, Y.; Rushmore, J.; Zekelman, L.; Makris, N.; Rathi, Y.; Golby, A. J.; Zhang, F.; O'Donnell, L. J.
10.1101/2024.10.19.619237 — neuroscience — Posted on 2024-10-22
1797 Competitive interactions shape brain dynamics and computation across species
Luppi, A. I.; Sanz Perl, Y.; Vohryzek, J.; Mediano, P. A. M.; Rosas, F. E.; Milisav, F.; Suarez, L. E.; Gini, S.; Gutierrez-Barragan, D.; Gozzi, A.; Misic, B.; Deco, G.; Kringelbach, M. L.
10.1101/2024.10.19.619194 — neuroscience — Posted on 2024-10-22
1804 LP-Micro Offers Interpretable Disease Outcome Prediction by Leveraging Microbial Biomarkers and Their Time-Varying Effects
Dai, Y.; Qian, Y.; Qu, Y.; Guan, W.; Xie, J.; Butler, C.; Dashper, S.; Carroll, I.; Divaris, K.; Liu, Y.; Wu, D.
10.1101/2024.10.18.619118 — bioinformatics — Posted on 2024-10-22
1809 Computational design of bifaceted protein nanomaterials with tailorable properties
Rankovic, S.; Carr, K. D.; Decarreau, J.; Skotheim, R.; Kibler, R. D.; Ols, S.; Lee, S.; Chun, J.-H.; Tooley, M.; Dauparas, J.; Eisenach, H. E.; Gloegl, M.; Weidle, C.; Borst, A. J.; Baker, D.; King, N. P.
10.1101/2024.10.18.619149 — bioengineering — Posted on 2024-10-22
1812 Artificial Selection and the Skin Microbiome Independently Predict Parasite Resistance
Kramp, R. D.; Janecka, M.; Tardent, N.; Jokela, J.; Kohl, K. D.; Stephenson, J. F.
10.1101/2024.10.19.619196 — ecology — Posted on 2024-10-22
1813 Novel replication-competent reporter-expressing Rift Valley fever viruses for molecular studies
Nogales, A.; Alonso, C.; Moreno, S.; Lorenzo, G.; Borrego, B.; Martinez-Sobrido, L.; Brun, A.
10.1101/2024.08.06.606778 — microbiology — Posted on 2024-10-22
1814 Deficiency of Hv1 Proton Channel Enhances Macrophage Antigen Presentation and Anti-Tumor Responses in Glioma
Zheng, J.; Wang, L.; Zhao, S.; Ayasoufi, K.; Goddery, E. N.; Strege, P. R.; Wan, Y.; Zhang, W.; Xie, M.; Beyder, A.; Johnson, A.; Wu, L.-J.
10.1101/2024.10.18.619142 — neuroscience — Posted on 2024-10-22
1815 ALDH1 subtype-specific inhibitor targets key cell populations in triple negative breast cancer
PEREZ, M.; Farres, J.; Rebollido-Rios, R.; Constantinescu, A.; Pequerul, R.; Janji, B.; Kumar, A.; Pares-Casampera, X.; Colignon, D.; Berrou, A.; Fournet, G.; Martin, G.; Ceylan, I.
10.1101/2024.10.18.619128 — cancer biology — Posted on 2024-10-22
1816 Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer
Wei, K.; Hill, B. L.; Miller, Z. A.; Mueller, A.; Thompson, J. C.; Lee, R. J.; Carey, R. M.
10.1101/2024.10.18.618693 — cancer biology — Posted on 2024-10-22
1817 Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapy
Behera, V.; Giba, H.; Pen, U.-Y.; Di Lello, A.; Doran, B. A.; Esposito, A.; Pezeshk, A.; Bestvina, C.; Kline, J.; Garassino, M.; Raman, A.
10.1101/2024.10.18.619136 — cancer biology — Posted on 2024-10-22
1818 Nicotinamide Metabolism Reprogramming Drives Reversible Senescence of Glioblastoma Cells
Narayanan, A.; Saurty-Seerunghen, M. S.; Michieletto, J.; Delaunay, V.; Bruneel, A.; Dupre, T.; Ottolenghi, C.; Pontoizeau, C.; Ciccone, L.; De La Vara, A.; Idbaih, A.; Turchi, L.; Virolle, T.; Chneiweiss, H.; Junier, M.-P.; EL-HABR, E. A.
10.1101/2024.10.18.619131 — cancer biology — Posted on 2024-10-22
1819 Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient
Truong Le, T.; Chen, K.-C.; Yi-Te Wan, D.; Yan, S. R.-G.; Chu, P.-Y.; Tan, T. Z.; Chiu, Y.-C.; Sheu, J.-Y.; Huang, C.-H.; Ye, J.; Tai, Y.-T.; Juan, H.-F.; Tsai, F.-C.; Lin, W.-C.; Wei, L.-H.; Huang, R. Y.-J.
10.1101/2024.10.19.619181 — cancer biology — Posted on 2024-10-22
1820 A rapid, facile, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies
Erath, J.; Kemper, D.; Mugo, E.; Jacoby, A.; Valenzuela, E.; Jungers, C. F.; Beatty, W. L.; Hashem, Y.; Jovanovic, M.; Djuranovic, S.; Djuranovic, S. P.
10.1101/2024.10.21.619433 — biochemistry — Posted on 2024-10-22
1821 In silico genomic surveillance by CoVerage predicts and characterizes SARS-CoV-2 Variants of Interest
Norwood, K.; Deng, Z.-L.; Reimering, S.; Robertson, G.; Foroughmand-Araabi, M.-H.; Goliaei, S.; Hoelzer, M.; McHardy, A. C.
10.1101/2024.03.07.583829 — bioinformatics — Posted on 2024-10-22
1822 Genetic diversity loss in the Anthropocene will continue long after habitat destruction ends
Mualim, K. S.; Spence, J. P.; Weiss, C. L.; Selmoni, O.; Lin, M.; Exposito-Alonso, M.
10.1101/2024.10.21.619096 — genomics — Posted on 2024-10-22
1823 A Practical and Safe Model of Nitrogen Mustard Injury in Cornea
Sandoval-Castellanos, A. M.; Ke, Y.; Dam, T. M.; Maverakis, E. M.; Mannis, M. J.; Wang, X.-J.; Zhao, M.
10.1101/2024.10.18.619116 — pharmacology and toxicology — Posted on 2024-10-22
1826 ER Aggregation Causes Synaptic Protein Imbalance in Retinitis Pigmentosa Mutant Photoreceptor Neurons
Thompson, S.; Crowder, S. M.; Hekmatara, M.; Sechrest, E. R.; Deng, W.-T.; Robichaux, M. A.
10.1101/2024.10.18.619115 — neuroscience — Posted on 2024-10-22
1827 Lifting the degeneracy of optical fiber neural interfaces for optogenetics and electrophysiology by using axialtrodes
Sui, K.; Codadu, N. K.; Rathore, D.; Li, G.; Meneghetti, M.; Berg, R. W.; Wykes, R. C.; Markos, C.
10.1101/2024.10.18.619110 — neuroscience — Posted on 2024-10-22
1831 Premature upregulation of miR-92a's target RBFOX2 hijacks PTBP splicing and impairs cortical neuronal differentiation.
Weissbach, S.; Todorov, H.; Schlichtholz, L.; Muehlbauer, S.; Zografidou, L.; Soliman, A.; Lor-Zade, S.; Hartwich, D.; Strand, D.; Vogel, T.; Heine, M.; Gerber, S.; Winter, J.
10.1101/2024.09.20.614071 — genomics — Posted on 2024-10-22
1832 Plasmid transmission dynamics and evolution of partner quality in a natural population of Rhizobium leguminosarum
Vereau Gorbitz, D.; Schwarz, C.; McMullen, J. G.; Ceron-Romero, M.; Doyle, R. T.; Lau, J. A.; Whitaker, R. J.; Vanderpool, C. K.; Heath, K.
10.1101/2024.10.17.618979 — genomics — Posted on 2024-10-22
1833 The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions
Gill, P.; Fonnelop, A. E.; Hicks, T.; Xenophontos, S.; Cariolou, M.; van Oorschot, R.; Buckel, I.; Sukser, V.; Papic, S.; Merkas, S.; Kostic, A.; Marques Pereira, A.; Teutsch, C.; Forsberg, C.; Haas, C.; Petkovski, E.; Hass, F.; Masek, J.; Stosic, J.; Lee, Y. S.; Syn, C. K.-C.; Groombridge, L.; Trimborn, M.; Hadjivassiliou, M.; Breathnach, M.; Novackova, J.; Parson, W.; Hatzer-Grubwieser, P.; Pietikoinen, S.; Joas, S.; Willuweit, S.; Grethe, S.; Milicevic, T.; Hasselqvist, T.; Kallupurackal, V.; Stenzl, V.; Jansson, S.; Glocker, I.; Brunck, S.; Nyhagen, K.; Dyve Lingelem, A. B.; Autere, H.; Th
10.1101/2024.10.10.617148 — genetics — Posted on 2024-10-22
1835 Unbounding fish: Assessing vulnerability to overexploitation for transboundary fish populations
Gangal, M.; Arthur, R.; Suri, V.; Pandit, A.; Tyagi, A.; Prakash, P.; Sule, M.; Majgaonkar, I.; Krishnaswamy, J.; Ramakrishnan, U.
10.1101/2024.07.12.603026 — ecology — Posted on 2024-10-22
1836 E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1
Matlock, W.; Rodger, G.; Pritchard, E.; Colpus, M.; Kapel, N.; Barrett, L.; Morgan, M.; Oakley, S.; Hopkins, K. L.; Roohi, A.; Karageorgopoulos, D.; Avison, M. B.; Walker, A. S.; Lipworth, S.; Stoesser, N.
10.1101/2024.08.12.607562 — microbiology — Posted on 2024-10-22
1838 Teichoic acids in the periplasm and cell envelope of Streptococcus pneumoniae
Mai, N.; Bauda, E.; Boyat, C.; Laguri, C.; Freton, C.; Chouquet, A.; Gallet, B.; Baudoin, M.; Wong, Y.-S.; Grangeasse, C.; Moriscot, C.; Durmort, C.; Zapun, A.; Morlot, C.
10.1101/2024.10.18.619035 — microbiology — Posted on 2024-10-22
1839 Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation
Roussel, T.; Hubas, C.; Halary, S.; Chynel, M.; Duval, C.; Cadoret, J.-P.; Meziane, T.; Vernes, L.; Yepremian, C.; Bernard, C.; Marie, B.
10.1101/2024.04.19.590274 — microbiology — Posted on 2024-10-22
1840 DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria
Dalia, T. N.; Machouri, M.; Lacrouts, C.; Fauconnet, Y.; Guerois, R.; Andreani, J.; Radicella, J. P.; Dalia, A. B.
10.1101/2024.10.21.619469 — microbiology — Posted on 2024-10-22
1841 Microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants
Weight, C. M.; Pollara, G. M.; Betts, M.; Ragazzini, R.; Connor, M.; Ramos-Sevillano, E.; Reine, J.; Whelan, M.; Guerra-Assuncao, J. A.; Bonfanti, P.; Jolly, C.; Noursadeghi, M.; Ferreira, D.; Brown, J.; Heyderman, R. S.
10.1101/2023.06.15.545009 — microbiology — Posted on 2024-10-22
1843 Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani
Pradhan, S.; Dhar, D.; Manna, D.; Chakraborty, S.; Bhattacharyya, A.; Chauhan, K.; Mukherjee, R.; Sen, A.; Pandey, K.; Das, S.; Mukherjee, B.
10.1101/2024.10.21.619374 — microbiology — Posted on 2024-10-22
1848 Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs
Dzwigonska, M.; Rosa, P.; Kaza, B.; Lipiec, S.; Cyranowski, S.; Ellert-Miklaszewska, A.; Kominek, A.; Obrebski, T.; Malik, A. R.; Piwocka, K.; Mieczkowski, J.; Kaminska, B.; Leszczynska, K. B.
10.1101/2024.09.12.612769 — cancer biology — Posted on 2024-10-22
1849 T Cell Traction Forces show temporal patterns which Depend on Stimulation and Cell Subtype
Mustapha, F.; Biarnes-Pelicot, M.; Torro, R.; El Husseiny, J.; Sengupta, K.; Puech, P.-H.
10.1101/2022.02.11.480084 — biophysics — Posted on 2024-10-22
1851 Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins
Rodriguez Palomo, I.; Nair, B. A. B.; Chiang, Y.; Dekker, J.; Dartigues, B.; Mackie, M.; Evans, M.; Macleod, R.; Olsen, J.; Collins, M. J.
10.1101/2023.12.15.571577 — bioinformatics — Posted on 2024-10-22
1853 Social ageing can protect against infectious disease in a group-living primate
Siracusa, E. R.; Pavez-Fox, M. A.; Negron-Del Valle, J. E.; Phillips, D.; Platt, M. L.; Snyder-Mackler, N.; Higham, J. P.; Brent, L. J. N.; Silk, M. J.
10.1101/2024.03.09.584237 — animal behavior and cognition — Posted on 2024-10-22
1857 Purging of highly deleterious alleles through an extreme bottleneck
Stuart, O. P.; Cleave, R.; Pearce, K.; Magrath, M. J.; Mikheyev, A. S.
10.1101/2024.07.23.602943 — evolutionary biology — Posted on 2024-10-22
1859 Diel and seasonal rhythmicity in activity and corticosterone in an Arctic migratory herbivore: A multifaceted approach
de Jong, M. E.; Slettenhaar, A. J.; Fokkema, R. W.; Leh, M.; Verhoeven, M. A.; Griffin, L. R.; Millesi, E.; Moe, B.; Barnreiter, E.; Loonen, M. J. J. E.; Scheiber, I. B. R.
10.1101/2024.08.30.610510 — ecology — Posted on 2024-10-22
1860 Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS
Scott, T. M.; Arnold, L. M.; Powers, J. A.; McCann, D. A.; Rowe, A. B.; Christensen, D. E.; Pereira, M. J.; Zhou, W.; Torrez, R. M.; Iwasa, J. H.; Kranzusch, P. J.; Sundquist, W. I.; Johnson, J. S.
10.1101/2024.04.22.590513 — microbiology — Posted on 2024-10-22
1861 Single-cell imaging of the lytic phage life cycle in bacteria
Wedd, C.; Yunusov, T.; Smith, A.; Li, R.; Hardo, G.; Hunter, M.; Majed, R.; Fusco, D.; Bakshi, S.
10.1101/2024.04.11.588870 — microbiology — Posted on 2024-10-22
1862 Fetal programming by the parental microbiome of offspring behavior, and DNA methylation and gene expression within the hippocampus
Gustafson, K. L.; Busi, S. B.; McAdams, Z. L.; McCorkle, R. E.; Khodakivskyi, P.; Bivens, N. J.; Davis, D. J.; Raju, M.; Coghill, L. M.; Goun, E. A.; Amos-Landgraf, J.; Franklin, C. L.; Wilmes, P.; Cortese, R.; Ericsson, A. C.
10.1101/2024.04.12.589237 — microbiology — Posted on 2024-10-22
1863 The functional type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful nodulation with Glycine max cv Pekin
Reyes-Perez, P.; Sanchez-Reina, A.; Civantos, C.; Moreno-de Castro, N.; Ollero, F. J.; Gandullo, J.; Jimenez-Guerrero, I.; Bernal, P.; Perez-Montano, F.
10.1101/2023.12.14.571490 — microbiology — Posted on 2024-10-22
1865 OCA-B promotes pathogenic maturation 1 of stem-like CD4+ T cells and autoimmune demyelination
Hughes, E. P.; Syage, A. R.; Mehrabad, E. M.; Lane, T. E.; Spike, B. T.; Tantin, D.
10.1101/2023.11.29.569210 — immunology — Posted on 2024-10-22
1867 Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome.
Wang, H.-B.; Smale, N. E.; Brown, S. H.; Villanueva, S. A.; Zhou, D.; Mulji, A.; Nguyen-Ngo, K.; Harvey, J. R.; Ghiani, C. A.; Colwell, C. S.
10.1101/2024.09.16.613343 — neuroscience — Posted on 2024-10-22
1868 Partial Correlation as a Tool for Mapping Functional-Structural Correspondence in Human Brain Connectivity
Santucci, F.; Jimenez-Marin, A.; Gabrielli, A.; Bonifazi, P.; Ibanez-Berganza, M.; Gili, T.; Cortes, J. M.
10.1101/2024.10.16.618230 — neuroscience — Posted on 2024-10-22
1872 In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET
Held, R. G.; Liang, J.; Esquivies, L.; Khan, Y. A.; Wang, C.; Azubel, M.; Brunger, A. T.
10.1101/2024.10.19.619226 — neuroscience — Posted on 2024-10-22
1874 Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein
Massaro Cenere, M.; Tiberi, M.; Paldino, E.; D'Addario, S. L.; Federici, M.; Giacomet, C.; Cutuli, D.; Matteocci, A.; Cossa, F.; Zarrilli, B.; Casadei, N.; Ledonne, A.; Petrosini, L.; Berretta, N.; Fusco, F. R.; Chiurchiu, V.; Mercuri, N. B.
10.1101/2024.01.30.577912 — neuroscience — Posted on 2024-10-22
1875 Mucilage Produced by Sorghum 1 (Sorghum bicolor) Aerial Roots Hosts Diazotrophs that Provide Significant Amounts of Nitrogen to the Plant
Venado, R. E.; Wilker, J.; Pankievicz, V.; Infante, V.; MacIntyre, A.; Wolf, E.; Vela, S.; Robbins, F. A.; Fernandes-Junior, P. I.; Vermerris, W.; Ane, J.-M.
10.1101/2023.08.05.552127 — plant biology — Posted on 2024-10-22
1876 Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis
Ojo, B. A.; Heo, L.; Fox, S. R.; Waddell, A.; Moreno-Fernandez, M. E.; Gibson, M.; Tran, T.; Dunn, A. L.; Elknawy, E. I. A.; Saini, N.; Lopez-Rivera, J. A.; Divanovic, S.; de Jesus Perez, V. A.; Rosen, M. J.
10.1101/2024.08.22.609271 — physiology — Posted on 2024-10-22
1877 An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma
Fraire, C. R.; Desai, K.; Obalapuram, U. A.; Mendyka, L. K.; Rajaram, V.; Sebastian, T.; Wang, Y.; Onel, K.; Lee, J.; Skapek, S. X.; Chen, K. S.
10.1101/2024.04.23.590638 — cancer biology — Posted on 2024-10-22
1880 A novel dataset of 2,362 equine fecal microbiomes from eight veterinary teaching hospital on three continents reveals dominant effects of geography, breed, and disease
McAdams, Z. L.; Campbell, E. J.; Dorfmeyer, R. A.; Turner, G.; Shaffer, S.; Ford, T.; Lawson, J.; Terry, J.; Raju, M.; Coghill, L.; Cresci, L.; Lascola, K.; Pridgen, T. L.; Blikslager, A.; Barrell, E.; Banse, H.; Paul, L.; Gillen, A.; Nott, S.; VandeCandelaere, M.; van Galen, G.; Townsend, K. S.; Martin, L. M.; Johnson, P. J.; Ericsson, A. C.
10.1101/2024.10.21.619412 — microbiology — Posted on 2024-10-22
1882 Quality assessment and control of unprocessed anatomical, functional, and diffusion MRI of the human brain using MRIQC
Hagen, M. P.; Provins, C.; MacNicol, E.; Li, J.; Gomez, T.; Garcia, M.; Seeley, S.; Haitz Legarreta, J.; Norgaard, M.; Bissett, P.; Poldrack, R. A.; Rokem, A. G.; Esteban, O.
10.1101/2024.10.21.619532 — neuroscience — Posted on 2024-10-22
1884 Structural compromise in spiking cortex and connected networks
Sahlas, E.; Avigdor, T.; Ngo, A.; Royer, J.; Lariviere, S.; Chen, J.; Xie, K.; Wang, Y.; Lam, J.; Rodriguez-Cruces, R.; Arafat, T.; Pana, R.; Bernasconi, A.; Bernasconi, N.; Frauscher, B.; Bernhardt, B.
10.1101/2024.10.19.619207 — neuroscience — Posted on 2024-10-22
1885 Ectomycorrhizal symbiosis evolved independently and by convergent gene duplication in rosid lineages
van Beveren, F.; Boele, Y.; Puginier, C.; Bianconi, M.; Libourel, C.; Bonhomme, M.; Keller, J.; Delaux, P.-M.
10.1101/2024.10.21.618687 — plant biology — Posted on 2024-10-22
1887 COmapper: High-resolution mapping of meiotic crossovers by long-read sequencing in Arabidopsis
Byun, D.; Son, N.; Kim, H.; Kim, J.; Park, J.; Park, S.-j.; Kim, H.; Kim, J.; Kim, J.; Lee, S.; Hyun, Y.; Ziolkowski, P. A.; Henderson, I. R.; Choi, K.
10.1101/2024.10.21.619347 — plant biology — Posted on 2024-10-22
1889 SIM and CCS52A1 control root hair cell endoreplication and expansion
Li, L.; Herburger, K.; Heyman, J.; Vercauteren, I.; De Veylder, L.
10.1101/2024.10.20.618934 — plant biology — Posted on 2024-10-22
1890 A circuit involving the lncRNA MB3 and the driver genes MYC and OTX2 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5
Grandioso, A.; Tollis, P.; Pellegrini, F. R.; Falvo, E.; Palma, A.; Migliaccio, F.; Belvedere, A.; Rea, J.; Tisci, G.; Carissimo, A.; Bozzoni, I.; Trisciuoglio, D.; Ballarino, M.; Ceci, P.; Laneve, P.
10.1101/2024.10.21.619459 — cancer biology — Posted on 2024-10-22
1891 Transcriptomic landscape identifies two unrecognized ependymoma subtypes and novel pathways in medulloblastoma
Arora, S.; Holland, E.; Vardharajan, S.; Taylor, M.; Sahm, F.; Mack, S. C.; Sievers, P.; Korshunov, A.; Nuechterlein, N.; Jensen, M.; Glatzer, G.
10.1101/2024.10.21.619495 — bioinformatics — Posted on 2024-10-22
1892 Olduvai domain expression downregulates mitochondrial pathways: implications for human brain evolution and neoteny
Keeney, J. G.; Astling, D.; Andries, V.; Vandepoele, K.; Anderson, N.; Davis, J. M.; Lopert, P.; Vandenbussche, J.; Gevaert, K.; Staes, A.; Paukovich, N.; Vogeli, B.; Jones, K. L.; van Roy, F.; Patel, M.; Sikela, J. M.
10.1101/2024.10.21.619278 — genomics — Posted on 2024-10-22
1895 Synaptic accumulation of GluN2B-containing NMDA receptors mediates the effects of BDNF-TrkB signalling on synaptic plasticity and in epileptogenesis
De Luca, P.; Mele, M.; Tanqueiro, S.; Napoli, F.; Butkeviciute, U.; Souto, A.; Costa, R.; Schwarz, A.; Drexel, M.; Sebastiao, A. M.; Diogenes, M.; Duarte, C. B.
10.1101/2024.10.21.618702 — neuroscience — Posted on 2024-10-22
1896 Evaluating signaling pathway inference from kinase-substrate interactions and phosphoproteomics data
Garrido-Rodriguez, M.; Potel, C.; Burtscher, M. L.; Becher, I.; Rodriguez-Mier, P.; Mueller-Dott, S.; Savitski, M. M.; Saez-Rodriguez, J.
10.1101/2024.10.21.619348 — systems biology — Posted on 2024-10-22
1898 NUDIX Hydrolases Target Specific Inositol Pyrophosphates and Regulate Phosphate and Iron Homeostasis, and the Expression of Defense Genes in Arabidopsis
Schneider, R.; Lami, K.; Prucker, I.; Stolze, S. C.; Strauss, A.; Langenbach, K.; Kamleitner, M.; Belay, Y. Z.; Ritter, K.; Furkert, D.; Gaugler, P.; Lange, E.; Faiss, N.; Schmidt, J. M.; Harings, M.; Krusenbaum, L.; Wege, S.; Kriescher, S.; The, J.; Schoof, H.; Fiedler, D.; Nakagami, H.; Giehl, R. F.; Lahaye, T.; Jessen, H. J.; Gaugler, V.; Schaaf, G.
10.1101/2024.10.18.619122 — plant biology — Posted on 2024-10-22
1900 Benzoxazinoid-mediated microbiome feedbacks enhance Arabidopsis growth and defense
Stengele, K.; Stauber, L.; Thoenen, L.; Janse van Rensburg, H.; D'Adda, V.; Schlaeppi, K.
10.1101/2024.10.21.619081 — plant biology — Posted on 2024-10-22
1901 H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress
Akter, S.; Perri, M.; Lavilla-Puerta, M.; Ferretti, B.; Dalle Carbonare, L.; Shukla, V.; Telara, Y.; Zhang, D.; Gunawardana, D. M.; Myers, W. K.; Giuntoli, B.; Flashman, E.; Licausi, F.
10.1101/2024.10.21.619351 — plant biology — Posted on 2024-10-22
1902 Cluster Assembly Dynamics Drive Fidelity of Planar Cell Polarity Polarization
Nissen, S. B.; Weiner, A. T.; Suyama, K. L.; Bosch, P. S.; Song, S.; Gu, Y.; Dunn, A. R.; Axelrod, J. D.
10.1101/2024.10.21.619498 — cell biology — Posted on 2024-10-21
1903 Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation
Hogrebe, N. J.; Schmidt, M. D.; Augsornworawat, P.; Gale, S. E.; Shunkarova, M.; Millman, J. R.
10.1101/2024.10.21.618465 — cell biology — Posted on 2024-10-21
1904 Glutamine Transport via Neurotransmitter Transporter 4 (NTT4, SLC6A17) Maintains Presynaptic Glutamate Supply at Excitatory Synapses in the Central Nervous System
Nicoli, A. L.; Al Abed, A. S.; Hulme, S. R.; Das, A.; Gauthier-Coles, G.; Bröer, A.; Balkrishna, S.; Burgio, G.; Dehorter, N.; Rae, C. D.; Bröer, S.; Billups, B.
10.1101/2024.10.20.616835 — neuroscience — Posted on 2024-10-21
1905 Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S elucidate the inhibitory effect against thrombosis
Shoara, A. A.; Slavkovic, S.; Neves, M.; Bhoria, P.; Prifti, V.; Chen, P.; Donaldson, L.; Beckett, A. N.; Johnson, P. E.; Ni, H.
10.1101/2024.10.21.619523 — biochemistry — Posted on 2024-10-21
1907 Hijacking and Integration of Algal Plastids andMitochondria in a Polar Planktonic Host
Rao, A. K.; Yee, D. P.; Chevalier, F.; Lekieffre, C.; Pavie, M.; Olivetta, M.; Dudin, O.; Gallet, B.; Hehenberger, E.; Seifi, M.; Jug, F.; Deschamps, J.; Wu, T.-D.; Gast, R.; Jouneau, P.-H.; Decelle, J.
10.1101/2024.10.20.619283 — ecology — Posted on 2024-10-21
1909 Extending sampling approaches for great crested newt (Triturus cristatus) eDNA monitoring
Harper, L. R.; Harper, K. J.; Platts, S.; Irwin, R.; Bennett, M.; Jones, B.; Taylor, O.; Plant, L.; Eccleshall, D.; Briscoe, A.; Gorman, L.; Stanhope, K.; Egeter, B.
10.1101/2024.10.21.619420 — ecology — Posted on 2024-10-21
1910 Targeted deletions in human mitochondrial DNA engineered by Type V CRISPR-Cas12a system
Nikitchina, N.; Heckel, A.-M.; Shebanov, N.; Mazunin, I.; Tarassov, I.; Entelis, N.
10.1101/2024.10.20.619292 — molecular biology — Posted on 2024-10-21
1913 Computational redesign of TALE proteins for DNA-templated assembly of protein fibers
de Haas, R. J.; Langowski, M. D.; Borst, A. J.; Pillai, V. V. S.; Hoffmann, G. E.; Bongers, M.; Cheng, S.; Treichel, C.; Leaf, E. M.; Wu, M.; Lynch, E. M.; Kollman, J. M.; Ruggeri, F. S.; Walkey, C.; de Vries, R.; King, N. P.
10.1101/2024.10.21.619424 — biochemistry — Posted on 2024-10-21
1914 Engineered Bxb1 variants improve integrase activity and fidelity
Rose, J.; Kim, H.; Von Stetina, J.; Thangavelu, M.; Conway, H.; O'Hara, M. S.; Hanna, P.; Biondi, T.; Dunyak, M. T.; Finn, J. D.; Kumar, S.; Cochrane, J. C.
10.1101/2024.10.21.619419 — biochemistry — Posted on 2024-10-21
1917 Fusarium graminearum copper amine-oxidases redundantly increase virulence by converting tryptamine from hydrolyzed plant defense compounds into auxin
Svoboda, T.; Ceranic, A.; Spoerhase, P.; Bartolomaeus, A.; Wiesenberger, G.; Fruhmann, P.; Beltran, E.; Berthiller, F.; Krska, R.; Schuhmacher, R.; Adam, G.
10.1101/2024.10.21.619423 — molecular biology — Posted on 2024-10-21
1918 A spatiotemporal atlas of human spermatogenesis based on single-cell transcriptomics and multiplex antibody imaging
Hikmet, F.; Mear, L.; Gustavsson, J.; Miranda, G.; Zhang, C.; Katona, B.; Schutten, R.; von Feilitzen, K.; Forsberg, M.; Stukenborg, J.-B.; Uhlen, M.; Lindskog, C.
10.1101/2024.10.21.619380 — molecular biology — Posted on 2024-10-21
1919 Fatty acid desaturases link cell metabolism pathways to promote proliferation of Epstein-Barr virus-infected B cells
Bonglack, E. N.; Hill, K. K.; Barry, A. P.; Bartlett, A.; Castellano-Escuder, P.; Hirschey, M. D.; Luftig, M. A.
10.1101/2024.10.21.619359 — microbiology — Posted on 2024-10-21
1920 An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs
Brancucci, N. M. B.; Gumpp, C.; van Gemert, G. J.; Yu, X.; Passecker, A.; Nardella, F.; Thommen, B. T.; Chambon, M.; Turcatti, G.; Halby, L.; Blasco, B.; Duffey, M.; Arimondo, P. B.; Bousema, T.; Scherf, A.; Leroy, D.; Kooij, T. W. A.; Rottmann, M.; Voss, T. S.
10.1101/2024.10.21.619440 — microbiology — Posted on 2024-10-21
1921 The Streptococcus pyogenes mannose phosphotransferase system (Man-PTS) influences antimicrobial activity and niche-specific nasopharyngeal infection
Marple, A. C.; Shannon, B. A.; Rishi, A.; Estafanos, L.; Armstrong, B. D.; Guariglia-Oropeza, V.; Tuffs, S. W.; McCormick, J. K.
10.1101/2024.10.21.619399 — microbiology — Posted on 2024-10-21
1924 DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria
Dalia, T. N.; Machouri, M.; Lacrouts, C.; Fauconnet, Y.; Andreani, J.; Guerois, R.; Radicella, J. P.; Dalia, A. B.
10.1101/2024.10.21.619469 — microbiology — Posted on 2024-10-21
1925 Neural and behavioral reinstatement jointly reflect retrieval of narrative events
Nau, M.; Greene, A.; Tarder-Stoll, H.; Lossio-Ventura, J. A.; Pereira, F.; Chen, J.; Baldassano, C.; Baker, C.
10.1101/2024.10.19.619187 — neuroscience — Posted on 2024-10-21
1927 Autonomous biogenesis of the entire protein translation machinery excluding ribosomes
Schwarz-Schilling, M.; Dupin, A.; Avidan, N.; Barak, Y.; Shimizu, Y.; Daube, S. S.; Bar-Ziv, R. H.
10.1101/2024.10.20.619270 — synthetic biology — Posted on 2024-10-21
1928 Engineering Resilient Gene Drives Towards Sustainable Malaria Control: Predicting, Testing and Overcoming Target Site Resistance
Morianou, I.; Phillimore, L.; Khatri, B. S.; Marston, L.; Gribble, M.; Burt, A.; Bernardini, F.; Hammond, A. M.; Nolan, T.; Crisanti, A.
10.1101/2024.10.21.618489 — synthetic biology — Posted on 2024-10-21
1931 SUPPRESSION OF AEDES AEGYPTI BY STERILE INSECT TECHNIQUE (SIT) ON CAPTIVA ISLAND, FLORIDA, USA FROM 2020 TO 2022
Morreale, R.; Carvalho, D. O.; Stenhouse, S.; Bajonero, J.; Pereira, R.; Hahn, D. A.; Lloyd, A.; Hoel, D. F.
10.1101/2024.10.18.618919 — ecology — Posted on 2024-10-21
1940 A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.
Nguyen, Q. H.; Lai, C. H. R.; Norris, M. J.; Ng, D.; Shah, M.; Lai, C. C.-L.; Isenman, D. E.; Moraes, T. F.
10.1101/2024.10.21.619360 — microbiology — Posted on 2024-10-21
1943 Crystallographic and NMR studies of Streptococcus pneumonia LCP protein PsrSp indicate the importance of dynamics in four long loops for ligand specificity
Sandalova, T.; Sala, B. M.; Moche, M.; Ljunggren, H.-G.; Alici, E.; Henriques-Normark, B.; Agback, T.; Lesovoy, D.; Agback, P.; Achour, A.
10.1101/2024.10.21.619401 — microbiology — Posted on 2024-10-21
1948 ACSS2 regulates ferroptosis in an E2F1-dependent manner in breast cancer brain metastatic cells
Esquea, E.; Young, R.; Ciraku, L.; Merzy, J.; Ahmed, N.; Talarico, A.; Karuppiah, M.; Gocal, W.; Simone, N.; Dick, A.; Reginato, M.
10.1101/2024.10.18.619082 — cancer biology — Posted on 2024-10-21
1950 DeepVul: A Multi-Task Transformer Model for Joint Prediction of Gene Essentiality and Drug Response
Jararweh, A.; Arredondo, D.; Macaulay, O.; Dicome, M.; Tafoya, L.; Hu, Y.; Virupakshappa, K.; Boland, G.; Flaherty, K.; Sahu, A.
10.1101/2024.10.17.618944 — bioinformatics — Posted on 2024-10-21
1951 Pelvic Ring Fractures: Does Spinopelvic Alignment Affect Sacral and Lumbopelvic Fixation Stability?
Tripathi, S.; Kumaran, Y.; Soehnlen, S.; Kelkar, A.; Seki, T.; Sakai, T.; Goel, V.; Quatman, C.; Nishida, N.
10.1101/2024.10.17.618950 — bioengineering — Posted on 2024-10-21
1953 Moving towards more holistic validation of machine learning-based approaches in ecology and evolution
Christensen, C.; Ferreira, A.; Cherono, W.; Maximiadi, M.; Nyaguthii, B.; Ogino, M.; Herrera, D.; Farine, D.
10.1101/2024.10.18.618969 — ecology — Posted on 2024-10-21
1955 Morphine-induced hyperalgesia impacts small extracellular vesicle miRNA composition and function
Reddy, D.; Lin, Z.; Ramanathan, S.; Luo, X.; Pande, R.; Tian, Y.; Side, C.; Barker, J. M.; Sacan, A.; Blendy, J. A.; Ajit, S. K.
10.1101/2024.10.17.617815 — neuroscience — Posted on 2024-10-21
1956 Wideband ratiometric measurement of tonic and phasic dopamine release in the striatum
Gottschalk, A.; Menees, H.; Bogner, C.; Zewde, S.; Jibin, J.; Gamam, A.; Flink, D.; Mosissa, M.; Bonneson, F.; Wehelie, H.; Alonso-Caraballo, Y.; Hamid, A. A.
10.1101/2024.10.17.618918 — neuroscience — Posted on 2024-10-21
1957 On the analysis of functional PET (fPET)-FDG: baseline mischaracterization can introduce artifactual metabolic (de)activations
Coursey, S. E.; Mandeville, J.; Reed, M. B.; Hartung, G. A.; Garimella, A.; Sari, H.; Lanzenberger, R.; Price, J. C.; Polimeni, J. R.; Greve, D. N.; Hahn, A.; Chen, J. E.
10.1101/2024.10.17.618550 — neuroscience — Posted on 2024-10-21
1961 Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women
Carleton, N.; Lee, S.; Li, R.; Zou, J.; Brown, D. D.; Hooda, J.; Chang, A.; Kumar, R.; Klei, L. R.; Rigatti, L. H.; Newsome, J.; John Mary, D. J. S.; Atkinson, J. M.; West, R. E.; Nolin, T. D.; Oberly, P. J.; Huang, Z.; Poirier, D.; Diego, E. J.; Lucas, P. C.; Tseng, G.; Lotze, M. T.; McAuliffe, P. F.; Zervantonakis, I. K.; Oesterreich, S.; Lee, A. V.
10.1101/2024.10.18.616978 — cancer biology — Posted on 2024-10-21
1964 Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter
Goyal, P.; Dhanabalan, K.; Scalise, M.; Friemann, R.; Indiveri, C.; Dobson, R. C.; Vinothkumar, K. R.; Subramanian, R.
10.1101/2024.03.29.587382 — biochemistry — Posted on 2024-10-21
1965 Zika and Dengue Viruses Differentially Modulate Host mRNA Processing Factors Defining Its Virulence
Scholl, A.; Gong, B.; Li, B.; Fatima, T.; Tirrell, N.; Karaiskos, S.; Rios, M.; Xu, J.; De, S.
10.1101/2024.10.18.619084 — genomics — Posted on 2024-10-21
1967 From Eggs to Guts: Symbiotic Association of Sodalis nezarae sp. nov. with the Southern Green Shield Bug Nezara viridula
Rogowska-van der Molen, M. A.; Manzano-Marin, A.; Postma, J. L.; Coolen, S.; van Alen, T.; Jansen, R. S.; Welte, C. U.
10.1101/2024.10.18.619066 — microbiology — Posted on 2024-10-21
1971 A Measure of Event-Related Potentials (ERP) Indices of Motivation During Cycling
Renoud-Grappin, R.; Gabriel, D.; Broussard, E.; Mourot, L.; Giustiniani, J.; Pazart, L.
10.1101/2024.10.18.619021 — neuroscience — Posted on 2024-10-21
1974 Cytoplasmic accumulation of a splice variant of hnRNP A2/B1 contributes to FUS-associated toxicity in a mouse model of ALS
Rossi, S.; Milani, M.; Della Valle, I.; Bisegna, S.; Durante, V.; Addesse, M.; D'Avorio, E.; Di Salvio, M.; Serafino, A.; Cestra, G.; Apolloni, S.; D'Ambrosi, N.; Cozzolino, M.
10.1101/2024.10.17.618866 — neuroscience — Posted on 2024-10-21
1975 Does Unfairness Evoke Anger or Disgust? A Quantitative Neurofunctional Dissection Based on 25 Years of Neuroimaging
Gan, X.; Zhang, R.; Zheng, Z.; Wang, L.; Yang, X.; Klugah-Brown, B.; Xu, T.; Qiu, N.; Kendrick, K. M.; Mathiak, K.; Tiwald, J.; Yao, D.; Becker, B.
10.1101/2024.10.17.618853 — neuroscience — Posted on 2024-10-21
1976 Neuronal TDP-43 aggregation drives changes in microglial morphology prior to immunophenotype in amyotrophic lateral sclerosis
Swanson, M. E. V.; Mrkela, M.; Turner, C.; Curtis, M. A.; Faull, R. L. M.; Walker, A. K.; Scotter, E. L.
10.1101/2024.10.17.618941 — neuroscience — Posted on 2024-10-21
1977 Modelling human social vision with cinematic stimuli
Santavirta, S.; Paranko, B.; Seppala, K.; Hyona, J.; Nummenmaa, L.
10.1101/2024.10.18.618846 — neuroscience — Posted on 2024-10-21
1978 Building a model of sepsis: data integration unravels pathogenic mechanisms in severe P. aeruginosa infections.
Messina, F.; Rotondo, C.; Ladeira, L.; Properzi, M.; Dimartino, V.; Riccitelli, B.; Staumont, B.; Chillemi, G.; Geris, L.; Bocci, M. G.; Fontana, C.
10.1101/2024.10.17.618881 — systems biology — Posted on 2024-10-21
1980 Protein catabolites as blood-based biomarkers of aging physiology: Findings from the Dog Aging Project
Harrison, B. R.; Partida-Aguilar, M.; Marye, A.; Djukovic, D.; Kauffman, M.; Dunbar, M. D.; Mariner, B. L.; McCoy, B. M.; Algavi, Y. M.; Muller, E.; Baum, S.; Bamberger, T.; Raftery, D.; Creevy, K. E.; Dog Aging Project Consortium, ; Avery, A.; Borenstein, E.; Snyder-Mackler, N.; Promislow, D. E.
10.1101/2024.10.17.618956 — systems biology — Posted on 2024-10-21
1984 Sex and seasonal variations in melatonin suppression, and alerting response to light
Fazlali, F.; Lazar, R. R.; Yahya, F.; Stefani, O.; Spitschan, M.; Cajochen, C.
10.1101/2024.10.18.619012 — physiology — Posted on 2024-10-21
1986 Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis
Dalangood, S.; Hu, C.; Yuan, C.; Li, X.; Qiao, W.; Li, H.; Zhang, R.; Li, L.; Li, P.; Yu, X.; Yin, W.; Lu, J.; Gui, J.
10.1101/2024.10.18.618991 — cancer biology — Posted on 2024-10-21
1987 S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting fatty acid metabolism
Huang, H.; Yang, Y.; Zhang, Q.; Yang, Y.; Xiong, Z.; Mao, S.; Song, T.; Wang, Y.; Liu, Z.; Bu, H.; Zhang, L.; Zhang, L.
10.1101/2024.10.17.618873 — cancer biology — Posted on 2024-10-21
1988 IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation
Park, J. W.; Kwak, J.; Kim, K.-W.; Jung, S.; Nam, C. H.; Kim, H. J.; Lee, S. M.; Park, J.-H.; Yoo, J.; Shim, J.-K.; Kim, C.; Ahn, S.; Pusch, S.; Deimling, A. v.; Chang, J. H.; Kim, S. H.; Ju, Y. S.; Kang, S.-G.; Lee, J. H.
10.1101/2024.10.17.618976 — cancer biology — Posted on 2024-10-21
1989 Deletions Rate-Limit Breast and Ovarian Cancer Initiation
Houlahan, K.; Bihie, M.; Contreras, J. G.; Fulop, D.; Lopez, G.; Huang, H.-H.; Van Loo, P.; Curtis, C.; Boutros, P.; Huang, K.-l.
10.1101/2024.10.17.618945 — cancer biology — Posted on 2024-10-21
1997 ProtNote: a multimodal method for protein-function annotation
Char, S.; Corley, N.; Alamdari, S.; Yang, K. K.; Amini, A. P.
10.1101/2024.10.17.618952 — bioengineering — Posted on 2024-10-21
1998 Control of 3' splice site selection by the yeast splicing factor Fyv6
Senn, K.; Lipinski, K.; Zeps, N. J.; Griffin, A. F.; Wilkinson, M. E.; Hoskins, A.
10.1101/2024.05.04.592262 — biochemistry — Posted on 2024-10-21
2000 Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine
Elmas, A.; Layden, H.; Ellis, J.; Barlett, L.; Zhao, X.; Kawabata-Iwakawa, R.; Obinata, H.; Hiebert, S.; Huang, K.-l.
10.1101/2024.10.17.618926 — genomics — Posted on 2024-10-21
2003 Polymorphisms in rs2069845 are associated with IL-6 and soluble IL-6 receptor levels during total joint replacement
Anderson, K. D.; Dulion, B.; Wong, J.; Patel, N.; DeBenedetti, A.; Della Valle, C. J.; Ross, R.
10.1101/2024.10.18.619020 — genetics — Posted on 2024-10-21
2006 Transgenerational chromosome repair in the asexual bdelloid rotifer Adineta vaga
Houtain, A.; Derzelle, A.; Lliros, M.; Hespeels, B.; Nicolas, E.; Simion, P.; Virgo, J.; Lenormand, T.; Hallet, B.; Van Doninck, K.
10.1101/2024.01.25.577190 — evolutionary biology — Posted on 2024-10-21
2008 Phosphorus availability as the primary determinant of nutrient limitation in temperate biodiverse herbaceous vegetation
Van Sundert, K.; van Diggelen, R.; D'Haese, J.; Aggenbach, C. J. S.; Dammers, E.; Findeisen, S.; Kotowski, W.; Kozub, L.; Kranenburg, R.; van der Bij, A.; Emsens, W.-J.
10.1101/2024.10.18.619065 — ecology — Posted on 2024-10-21
2011 Modeling the spatio-temporal annual changes in human tick-borne encephalitis (TBE) risk in Europe
Dagostin, F.; Erazo Quintero, D.; Marini, G.; Da Re, D.; Tagliapietra, V.; Avdicova, M.; Avsic-Zupanc, T.; Dub, T.; Fiorito, N.; Knap, N.; Gossner, C. M.; Kerlik, J.; Makela, H.; Markowicz, M.; Olyazadeh, R.; Richter, L.; Wint, W.; Zuccali, M. G.; Zygutiene, M.; Dellicour, S.; Rizzoli, A.
10.1101/2024.10.18.619031 — ecology — Posted on 2024-10-21
2012 Reversal of vein of Galen aneurysmal malformation by stimulation of flow-mediated vessel fusion
Martin-Valiente, E.; Du, Y.; Goemans, C.; Zindy, E.; Adam, M.; Scheid, B.; Vikkula, M.; Lubicz, B.; Vanhollebeke, B.; Baeyens, N.
10.1101/2024.10.18.618370 — developmental biology — Posted on 2024-10-21
2013 Downregulation of PIK3IP1/TrIP on T cells is controlled by TCR signal strength, PKC, and metalloprotease-mediated cleavage
Murter, B. M.; Robinson, S. C.; Banerjee, H.; Lau, L.; Uche, U.; Szymczak-Workman, A. L.; Kane, L. P.
10.1101/2024.04.29.591680 — cell biology — Posted on 2024-10-21
2015 Olfactory combinatorial coding supports risk-reward decision making in C. elegans
Saad, M. Z. H.; Ryan, W. G.; Edwards, C. A.; Szymanski, B. N.; Marri, A. R.; Jerow, L. G.; McCullumsmith, R.; Bamber, B. A.
10.1101/2024.06.19.599745 — neuroscience — Posted on 2024-10-21
2016 Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory
Yamawaki, N.; Login, H.; Feld-Jakobsen, S. O.; Molnar, B. M.; Kirkegaard, M. Z.; Moltesen, M.; Okrasa, A.; Radulovic, J.; Tanimura, A.
10.1101/2024.03.17.585387 — neuroscience — Posted on 2024-10-21
2018 Evidence of microglial involvement in the childhood abuse-associated increase in perineuronal nets in the ventromedial prefrontal cortex
Belliveau, C.; Rahimian, R.; Fakhfouri, G.; Hosdey, C.; Simard, S.; Davoli, M. A.; Mirault, D.; Giros, B.; Turecki, G.; Mechawar, N.
10.1101/2024.03.08.584135 — neuroscience — Posted on 2024-10-21
2019 Foamy microglia link oxylipins to disease progression in multiple sclerosis
van der Vliet, D.; Di, X.; Shamorkina, T. M.; Pavlovic, A.; Van der Vliet, I. A. C. M.; Zeng, Y.; Macnair, W.; van Egmond, N.; Chen, J. Q. A.; van den Bosch, A. M. R.; Engelenburg, H. J.; Mason, M. R. J.; Coulon-Bainier, C.; Gagestein, B.; Dusseldorp, E.; van Eijk, M.; Grether, U.; Netherlands Brain Bank (NBB), ; Harms, A. C.; Hankemeier, T.; Collin, L.; Heck, A. J. R.; Huitinga, I.; van der Stelt, M.
10.1101/2024.10.18.619040 — neuroscience — Posted on 2024-10-21
2021 Topical administration of novel FKBP12 ligand MP-004 improves retinal function and structure in retinitis pigmentosa models.
Lara-Lopez, A.; Gonzalez-Imaz, K.; Rodriguez-Hidalgo, M.; Sarasola Gastesi, M.; Escudero-Arraras, L.; Milla-Navarro, S.; de la Villa, P.; Sagartzazu-Aizpurua, M.; Miranda, J. I.; Aizpurua, J. M.; Lopez de Munain, A.; Vallejo-Illarramendi, A.; Ruiz-Ederra, J.
10.1101/2024.10.17.618826 — neuroscience — Posted on 2024-10-21
2023 Orthogonalized human protease control of secreted signals
Aldrete, C. A.; Call, C. C.; Sant'Anna, L. E.; Vlahos, A. E.; Pei, J.; Cong, Q.; Gao, X. J.
10.1101/2024.01.18.576308 — synthetic biology — Posted on 2024-10-21
2024 Resolving an unconventional non-photochemical quenching signature at the light-to-dark transition
Lam, L.; Patel-Tupper, D.; Lam, H. E.; Steen, C. J.; Ma, A.; Ma, S. A.; Leipertz, A.; Lee, T.-Y.; Fleming, G.; Niyogi, K. K.
10.1101/2024.10.17.618902 — plant biology — Posted on 2024-10-21
2025 Nitrogen ionome dynamics on leafy vegetables in tropical climate
Shenhar, I.; Harikumar, A.; Trujillo, M. R. P.; Zhao, Z.; Lin, Q.; Setyawati, M. I.; Tan, D.; He, J.; Herman, I.; Ng, K. W.; Gavish, M.; Moshelion, M.
10.1101/2024.10.17.618770 — plant biology — Posted on 2024-10-21
2026 Transdermal Delivery of Ultradeformable Cationic Liposomes Complexed with miR211-5p (UCL-211) Stabilizes BRAFV600E+ Melanocytic Nevi
Chhibber, T.; Scherzer, M. T.; Prokofyeva, A.; Becker, C.; Zitnay, R. G.; Smith, E.; Khurana, N.; Skliar, M.; Deacon, D. C.; VanBrocklin, M. W.; Ghandehari, H.; Judson-Torres, R. L.; Jafari, P.
10.1101/2024.10.17.618694 — pharmacology and toxicology — Posted on 2024-10-21
2028 Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer
Sandulache, V. C.; LI, Y.; Yadollahi, P.; Essien, F.; Putluri, V.; Amara, C. S.; Reddy, K. R. K.; Kamal, A. H. M.; Putluri, N.; Abdurrahman, L. M.; Echartea, M. E. R.; Ernste, K. J.; Trivedi, A. J.; Vazquez-Perez, J.; Hudson, W. H.; Decker, W. K.; Patel, R. U.; Osman, A. A.; Kheradmand, F.; Lai, S. Y.; Myers, J. N.; Skinner, H. D.; Coarfa, C.; Lee, K.; Jain, A.; Malovannaya, A.; Frederick, M. J.
10.1101/2024.10.17.618907 — cancer biology — Posted on 2024-10-21
2030 PROPERMAB: an integrative framework for in silico prediction of antibody developability using machine learning
Li, B.; Luo, S.; Wang, W.; Xu, J.; Liu, D.; Shameem, M.; Mattila, J.; Franklin, M.; Hawkins, P. G.; Atwal, G. S.
10.1101/2024.10.10.616558 — bioinformatics — Posted on 2024-10-21
2031 Decipher Fundamental Atomic Interactions to Unify Generative Molecular Docking and Design
Peng, X.; Guo, R.; Xu, Y.; Guan, J.; Jia, Y.; Huang, Y.; Zhang, M.; Peng, J.; Sun, J.; Han, C.; Wang, Z.; Ma, J.
10.1101/2024.10.17.618827 — bioinformatics — Posted on 2024-10-21
2032 A long context RNA foundation model for predicting transcriptome architecture
Saberi, A.; Choi, B.; Wang, S.; Hernandez-Corchado, A.; Naghipourfar, M.; Namini, A.; Ramani, V.; Emad, A.; Najafabadi, H. S.; Goodarzi, H.
10.1101/2024.08.26.609813 — bioinformatics — Posted on 2024-10-21
2034 Machine learning prediction of enzyme optimum pH
Gado, J. E.; Knotts, M.; Shaw, A. Y.; Marks, D.; Gauthier, N. P.; Sander, C.; Beckham, G. T.
10.1101/2023.06.22.544776 — biochemistry — Posted on 2024-10-21
2035 Unwrapping the ciliary coat: high-resolution structure and function of the ciliary glycocalyx
Hoepfner, L. M.; Nievergelt, A. P.; Martino, F.; Scholz, M.; Foster, H. E.; Rodenfels, J.; von Appen, A.; Hippler, M.; Pigino, G.
10.1101/2024.09.28.615573 — cell biology — Posted on 2024-10-21
2036 Cooperative motility emerges in crowds of T cells but not neutrophils
Wortel, I. M. N.; Postat, J.; Mihaylova, M.; Merino, M.; Bhagrath, A.; Harris, M.; Wouters, L.; Wiebke, L.; Parisi, D. R.; Mandl, J. N.; Textor, J.
10.1101/2024.10.21.618803 — cell biology — Posted on 2024-10-21
2037 Apical clathrin-coated endocytic pits control the growth and size of epithelial microvilli
Perkins, O. L.; Mulligan, A. G.; Krystofiak, E. S.; Peebles, K. E.; Meenderink, L. M.; Millis, B. A.; Tyska, M. J.
10.1101/2024.10.21.619431 — cell biology — Posted on 2024-10-21
2038 TFAP2C and HNRNPK control mTOR cell metabolism and prion propagation
Sellitto, S.; Caredio, D.; Bimbati, M.; Mariutti, G.; Cerisoli, M.; Frick, L.; Bouris, V.; Morales, C. O. O.; Vena, D. L.; Neupane, S.; Baroni, F.; Ging, K.; Yin, J.-A.; De Cecco, E.; Armani, A.; Aguzzi, A.
10.1101/2024.10.21.619371 — cell biology — Posted on 2024-10-21
2041 Elevated DNA Damage without signs of aging in the short-sleeping Mexican Cavefish
Lloyd, E.; Xia, F.; Moore, K.; Zertuche, C.; Rastogo, A.; Kozol, R.; Kenzior, O.; Warren, W. C.; Appelbaum, L.; Moran, R. L.; Zhao, C.; Duboue, E. R.; Rohner, N. R.; Keene, A. C.
10.1101/2024.04.18.590174 — neuroscience — Posted on 2024-10-21
2042 Style deflection is determined by the handedness of phyllotaxis and auxin-induced differential cell elongation in a species with mirror-image flowers
Robertson, C.; Xue, H.; Saltini, M.; Fairnie, A. L. M.; Lang, D.; Kerstens, M. H. L.; Willemsen, V.; Ingle, R. A.; Barrett, S. C. H.; Deinum, E. E.; Illing, N.; Lenhard, M.
10.1101/2024.06.14.598852 — plant biology — Posted on 2024-10-21
2043 University Exams and Psychosocial Stress: Effects on Cortisol Rhythmicity in Students
Borghi, F.; da Silva, P. C.; Farias-Silva, E.; Canova, F.; Souza, A. L.; Barbedo Arouca, A.; Grassi-Kassisse, D. M.
10.1101/2021.02.23.432585 — physiology — Posted on 2024-10-21
2046 Latent generative modeling of long genetic sequences with GANs
Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Yelmen, B.; Jay, F.
10.1101/2024.08.07.607012 — genomics — Posted on 2024-10-21
2048 Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain
Peach, C. J.; Tonello, R.; Damo, E.; Gomez, K.; Calderon-Rivera, A.; Bruni, R.; Bansia, H.; Maile, L.; Manu, A.-M.; Hahn, H.; Thomsen, A. R. B.; Schmidt, B. L.; Davidson, S.; des Georges, A.; Khanna, R.; Bunnett, N. W.
10.1101/2023.12.06.570398 — neuroscience — Posted on 2024-10-21
2049 Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep
Turi, G. F.; Teng, S.; Chen, X.; Lim, E. C.; Dias, C.; Hu, R.; Wang, R.; Zhen, F.; Peng, Y.
10.1101/2023.05.12.540575 — neuroscience — Posted on 2024-10-21
2051 Progressive changes in functional connectivity between thalamic nuclei and cortical networks across learning
Jarrett, C. E.; Zwosta, K.; Wang, X.; Wolfensteller, U.; Iglesias, J. E.; von Kriegstein, K.; Ruge, H.
10.1101/2024.08.26.609333 — neuroscience — Posted on 2024-10-21
2052 Brain activity discriminates acoustic simulations of the same environment
Matten, V. G.; Stirnberg, R.; van de Par, S.; Ewert, S.; Flanagin, V. L.
10.1101/2024.08.29.610373 — neuroscience — Posted on 2024-10-21
2054 Creating a biomedical knowledge base by addressing GPT inaccurate responses and benchmarking context
Darnell, S. S.; Overall, R.; Guarracino, A.; Colonna, V.; Villani, F.; Garrison, E.; Isaac, A.; Muli, P.; Muriithi, F. M.; Kabui, A.; Kilungi, M. B.; Kibet, A.; Lisso, F.; Muhia, B.; Nijveen, H.; Yousefi, S.; Ashbrook, D. G.; Huang, P.; Suh, E.; Umar, M.; Batten, C.; Chen, H.; Sen, S.; Williams, R. W.; Prins, P.
10.1101/2024.10.16.618663 — scientific communication and education — Posted on 2024-10-21
2055 Natural killer cell cytotoxicity shapes the clonal evolution of B cell leukaemia
Buri, M. C.; Shoeb, M. R.; Bykov, A.; Repiscak, P.; Baik, H.; Dupanovic, A.; David, F. O.; Kovacic, B.; Hall-Glenn, F.; Dopa, S.; Urbanus, J.; Sippl, L.; Stofner, S.; Emminger, D.; Cosgrove, J.; Schinnerl, D.; Poetsch, A. R.; Lehner, M.; Koenig, X.; Perie, L.; Shumacher, T. N.; Gotthardt, D.; Halbritter, F.; Putz, E. M.
10.1101/2023.11.16.567430 — cancer biology — Posted on 2024-10-21
2056 Molecular mechanism of thyroxine transport by monocarboxylate transporters
Tassinari, M.; Tanzi, G.; Maggiore, F.; Groeneweg, S.; van Geest, F. S.; Freund, M.; Stavast, C. J.; Boniardi, I.; Pasqualato, S.; Visser, W. E.; Coscia, F.
10.1101/2024.10.17.618737 — biochemistry — Posted on 2024-10-21
2064 miR-210 locus deletion disrupts cellular homeostasis; an integrated genetic study
Preda, M. B.; Rusu-Nastase, E. G.; Neculachi, C. A.; Zhong, X.; Voellenkle, C.; Mazure, N. M.; Balacescu, O.; Ivan, C.; Zheng, X.; Gherghiceanu, M.; Le brigand, K.; Simionescu, M.; Martelli, F.; Catrina, S.-B.; Burlacu, A.; Ivan, M.
10.1101/2024.10.18.619004 — molecular biology — Posted on 2024-10-21
2066 Functional study of Phaeodactylum tricornutum Seipin homolog highlights unique features of lipid droplets biogenesis in diatoms.
Le Moigne, D.; Richard, F.; Albrieux, C.; Mahieu, M.; Arrighi, M.; Si Larbi, G.; jouneau, P.-H.; Gros, V.; Louwagie, M.; Roy, S.; Amari, C.; Carletti, M.; Bonnarde, R.; Gong, Y.; Pan, Y.; Hu, H.; Bastien, O.; Jouhet, J.; Amato, A.; Marechal, E.; Salvaing, J.
10.1101/2024.10.11.617903 — plant biology — Posted on 2024-10-21
2069 Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation
Dahmane, S.; Schexnaydre, E.; Zhang, J.; Rosendal, E.; Chotiwan, N.; Kumari Singh, B.; Yau, W.-L.; Lundmark, R.; Barad, B.; Grotjahn, D. A.; Liese, S.; Carlson, A.; Overby, A.; Carlson, L.-A.
10.1101/2024.10.13.618056 — microbiology — Posted on 2024-10-21
2070 Brain activity discriminates acoustic simulations of the same environment
Matten, V. G.; Stirnberg, R.; van de Par, S.; Ewert, S.; Flanagin, V. L.
10.1101/2024.08.29.610373 — neuroscience — Posted on 2024-10-21
2071 YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution
Faraji, F.; Ramirez, S. I.; Clubb, L.; Sato, K.; Burghi, V.; Hoang, T. S.; Officer, A.; Anguiano Quiroz, P. Y.; Galloway, W. M.; Mikulski, Z.; Medetgul-Ernar, K.; Marangoni, P.; Jones, K. B.; Molinolo, A. A.; Kim, K.; Sakaguchi, K.; Califano, J. A.; Smith, Q.; Goren, A.; Klein, O. D.; Tamayo, P.; Gutkind, J. S.
10.1101/2023.07.24.550427 — cancer biology — Posted on 2024-10-21
2072 Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight
Nourbakhsh, M.; Zheng, Y.; Noor, H.; Chen, H.; Akhuli, S.; Tiberti, M.; Gevaert, O.; Papaleo, E.
10.1101/2024.03.14.584946 — bioinformatics — Posted on 2024-10-21
2073 Sustained ROS Scavenging and Pericellular Oxygenation by Lignin Composites Rescue HIF-1α and VEGF Levels to Improve Diabetic Wound Neovascularization and Healing
Jung, J. P.; Olutoye, O. O.; Prajapati, T. J.; Jung, O. S.; Yutzy, L. D.; Nguyen, K. L.; Wheat, S. W.; Huang, J.; Padon, B. W.; Faruk, F.; Keswani, S. S.; Kogan, P.; Kaul, A. A.; Yu, L.; Li, H.; Thevasagayampillai, S.; Guerra, M. E.; Short, W. D.; Gunaratne, P. H.; Balaji, S.
10.1101/2022.06.18.496670 — bioengineering — Posted on 2024-10-21
2078 An interkinetic envelope surrounds chromosomes between meiosis I and II in C. elegans oocytes
El Mossadeq, L.; Bellutti, L.; Le Borgne, R.; Canman, J. C.; PINTARD, L.; Verbavatz, J.-M.; Askjaer, P.; Dumont, J.
10.1101/2024.10.19.619195 — cell biology — Posted on 2024-10-21
2080 Replication-dependent histone (Repli-Histo) labeling dissects the physical properties of euchromatin/heterochromatin in living human cells.
Minami, K.; Ide, S.; Nakazato, K.; Kaizu, K.; Higashi, K.; Tamura, S.; Toyoda, A.; Takahashi, K.; Kurokawa, K.; Maeshima, K.
10.1101/2024.10.20.618801 — cell biology — Posted on 2024-10-21
2082 Intrinsic Diversity in Primary Cilia Revealed Through Spatial Proteomics
Lundberg, E.; Hansen, J.; Sun, H.; Kahnert, K.; Johannesson, A.; Tzavlaki, K.; Winsnes, C.; Pohjahnen, E.; Fall, J.; Uhlen, M.; Axelsson, U.; Navarro, F. B.; Backstrom, A.; Lindskog, C.; Johansson, F.; von Feilitzen, K.; Vega, A. D.; Casals, A. M.; Mahdessian, D.; Lindstrand, A.; Westenius, E.
10.1101/2024.10.20.619273 — cell biology — Posted on 2024-10-21
2083 In vivo functional profiling and structural characterisation of the human Glp1r A316T variant
El Eid, L.; Deane-Alder, K.; Rujan, R.-M.; Mariam, Z.; Oqua, A. I.; Manchanda, Y.; Belousoff, M. J.; Bernardino de la Serna, J.; Sloop, K. W.; Rutter, G. A.; Montoya, A.; Withers, D. J.; Millership, S.; Bouzakri, K.; Jones, B.; Reynolds, C. A.; Sexton, P. M.; Wootten, D.; Deganutti, G.; Tomas, A.
10.1101/2024.10.19.619191 — cell biology — Posted on 2024-10-21
2085 Precise amplification-free detection of highly structured RNA with an enhanced SCas12a assay
Zhang, J.; Jiang, Q.; Deng, W.; Jin, S.; Wang, X.; He, R.; Yin, W.; Qiao, J.; Liu, Y.
10.1101/2024.10.20.619274 — molecular biology — Posted on 2024-10-21
2087 ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer
Stojanovic, L.; Abbotts, R.; Tripathi, K.; Coon, C. M.; Rajendran, S.; Abbasi Farid, E.; Hostetter, G.; Guarnieri, J. W.; Wallace, D. C.; Liu, S.; Wan, J.; Calendo, G.; Marker, R.; Gohari, Z.; Inayatullah, M. M. A.; Tiwari, V. K.; Kader, T.; Santagata, S.; Drapkin, R.; Kommoss, S.; Pfisterer, J.; Konecny, G. E.; Coopergard, R.; Issa, J.-P.; Winterhoff, B. J. N.; Topper, M. J.; Sandusky, G. E.; Miller, K. D.; Baylin, S. B.; Nephew, K. P.; Rassool, F. V.
10.1101/2024.10.18.618659 — cancer biology — Posted on 2024-10-21
2092 Molecular Specification of Claustro-Amygdalar and Paleocortical Neurons and Connectivity
Kaur, N.; Kovner, R.; Gulden, F. O.; Pletikos, M.; Andrijevic, D.; Zhu, T.; Silbereis, J.; Ma, S.; Salla, N.; Martin, X. d.; Klaric, T. S.; Liu, Y.; Shibata, A.; Franjic, D.; Cho, H.; Yuen, M.; Chatterjee, I.; Burke, M.; Esakkimuthu, D.; Moser, M.; Santpere, G.; Mineur, Y. S.; Pattabiraman, K.; Picciotto, M. R.; Huang, H.; Sestan, N.
10.1101/2024.10.20.619229 — neuroscience — Posted on 2024-10-20
2093 Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons
Su, X.; Zhang, H.; Hong, Y.; Yang, Q.; Wang, L.; Le, T.; Liu, J.; Cheruvu, L.; Labour, E.; Zhang, S.; Mendez-Maldonado, K.; Kreimer, A.; Song, H.; Ming, G.-L.; Duan, J.; Pang, Z. P.
10.1101/2024.10.20.619313 — neuroscience — Posted on 2024-10-20
2095 deadtrees.earth - An Open-Access and Interactive Database for Centimeter-Scale Aerial Imagery to Uncover Global Tree Mortality Dynamics
Mosig, C.; Vajna-Jehle, J.; Mahecha, M. D.; Cheng, Y.; Hartmann, H.; Montero, D.; Junttila, S.; Horion, S.; Schwenke, M. B.; Adu-Bredu, S.; Al-Halbouni, D.; Allen, M.; Altman, J.; Angiolini, C.; Astrup, R.; Barrasso, C.; Bartholomeus, H.; Brede, B.; Buras, A.; Carrieri, E.; Chirici, G.; Cloutier, M.; Cushman, K.; Dalling, J. W.; Dempewolf, J.; Denter, M.; Ecke, S.; Eichel, J.; Eltner, A.; Fabi, M.; Fassnacht, F.; Feirreira, M. P.; Frey, J.; Frick, A.; Ganz, S.; Garbarino, M.; Garcia, M.; Gassilloud, M.; Ghasemi, M.; Giannetti, F.; Gonzalez, R.; Gosper, C.; Greinwald, K.; Grieve, S.; Gutierrez,
10.1101/2024.10.18.619094 — ecology — Posted on 2024-10-20
2098 Synapsin condensation is governed by sequence-encoded molecular grammars
Hoffmann, C.; Ruff, K. M.; Edu, I.; Kyung Shinn, M.; Tromm, J.; King, M.; Pant, A.; Ausserwoeger, H.; Morgan, J.; Knowles, T.; Pappu, R. V.; Milovanovic, D.
10.1101/2024.08.03.606464 — biochemistry — Posted on 2024-10-20
2105 Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST
Kraus, F.; He, Y.; Swarup, S.; Overmyer, K. A.; Brenner, J.; Capitanio, C.; Bieber, A.; Jen, A.; Nightingale, N. M.; Anderson, B. J.; Lee, C.; Paulo, J. A.; Smith, I. R.; Plitzko, J. M.; Gygi, S. P.; Schulman, B. A.; Wilfling, F.; Coon, J. J.; Harper, J. W.
10.1101/2024.03.26.586828 — cell biology — Posted on 2024-10-20
2107 In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET
Held, R. G.; Liang, J.; Esquivies, L.; Khan, Y. A.; Wang, C.; Azubel, M.; Brunger, A. T.
10.1101/2024.10.19.619226 — neuroscience — Posted on 2024-10-20
2109 Components of Mnemonic Metacognition Constitutionally Supported by High Gamma Activity Between the Precuneus and Hippocampus
Pan, K.; Guo, X.; Zheng, Z.; Zhu, Z.; Wu, H.; Zhu, J.; Ye, H.; Cai, Y.; Santos-Pata, D.; Zhang, J.; Kwok, S. C.; Jiang, H.
10.1101/2024.02.26.581526 — neuroscience — Posted on 2024-10-20
2111 Pneumococcal biosynthesis gene mutants retain epithelial microinvasion and induce innate immunity
Weight, C. M.; Pollara, G. M.; Betts, M.; Ragazzini, R.; Connor, M.; Ramos-Sevillano, E.; Reine, J.; Whelan, M.; Guerra-Assuncao, J. A.; Bonfanti, P.; Jolly, C.; Noursadeghi, M.; Ferreira, D.; Brown, J.; Heyderman, R. S.
10.1101/2023.06.15.545009 — microbiology — Posted on 2024-10-20
2112 Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
Huang, Y.; Fan, Y.; Liu, Y.; Liu, X.; Li, W.; Yang, Y.; Zhang, Z.; Ma, S.; shuhui, j.; Chen, S.; Shu, H.; Feng, W.; Wang, K.; He, Q.; Qi, W.; Fan, Y.; Li, X.; Liu, M.
10.1101/2024.09.17.613598 — physiology — Posted on 2024-10-20
2114 Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy
Saez-Calveras, N.; Vaquer-Alicea, J.; White, C. L.; Tak, Y.; Cosentino, S.; Faust, P. L.; Louis, E. D.; Diamond, M. I.
10.1101/2024.10.12.617973 — pathology — Posted on 2024-10-20
2117 Chromosomal-level reference genome and microRNAs of the ricefield flatsedge Cyperus iria
Tsang, S. K.; Nong, W.; Law, S. T. S.; Bede, J. C.; Chen, S.-S.; Li, S.; Xie, Y.; Swale, T.; Lau, D. T. W.; Kai, Z.-p.; Chan, T. F.; Tobe, S. S.; Bendena, W.; Hui, J. H. L.
10.1101/2024.10.18.619046 — genomics — Posted on 2024-10-20
2118 deadtrees.earth - An Open-Access and Interactive Database for Centimeter-Scale Aerial Imagery to Uncover Global Tree Mortality Dynamics
Mosig, C.; Vajna-Jehle, J.; Mahecha, M. D.; Cheng, Y.; Hartmann, H.; Montero, D.; Junttila, S.; Horion, S.; Adu-Bredu, S.; Al-Halbouni, D.; Allen, M.; Altman, J.; Angiolini, C.; Astrup, R.; Barrasso, C.; Bartholomeus, H.; Brede, B.; Buras, A.; Carrieri, E.; Chirici, G.; Cloutier, M.; Cushman, K.; Dalling, J. W.; Dempewolf, J.; Denter, M.; Ecke, S.; Eichel, J.; Eltner, A.; Fabi, M.; Fassnacht, F.; Feirreira, M. P.; Frey, J.; Frick, A.; Ganz, S.; Garbarino, M.; Garcia, M.; Gassilloud, M.; Ghasemi, M.; Giannetti, F.; Gonzalez, R.; Gosper, C.; Greinwald, K.; Grieve, S.; Gutierrez, J. A.; Goeritz,
10.1101/2024.10.18.619094 — ecology — Posted on 2024-10-20
2119 inTRACKtive - A Web-Based Tool for Interactive Cell Tracking Visualization
Huijben, T. A. P. M.; Anderson, A. G.; Sweet, A.; Hoops, E.; Larsen, C.; Awayan, K.; Bragantini, J.; Chiu, C.-L.; Royer, L. A.
10.1101/2024.10.18.618998 — developmental biology — Posted on 2024-10-20
2124 sv-channels: filtering genomic deletions using one-dimensional convolutional neural networks
Santuari, L.; Georgievska, S.; Kuzniar, A.; Pedersen, B. S.; Shneider, C.; Mehrem, S.; Ridder, L.; Kloosterman, W. P.; de Ridder, J.
10.1101/2024.10.17.618894 — bioinformatics — Posted on 2024-10-20
2125 Integrating target capture with whole genome sequencing of recent and natural history collections to explain the phylogeography of wild-growing and cultivated Cannabis
Balant, M.; Vitales, D.; Wang, Z.; Barina, Z.; Fu, L.; Gao, T.; Garnatje, T.; Gras, A.; Hayat, M. Q.; Oganesian, M.; Pellicer, J.; Salami, A. S.; Seregin, A. P.; Stepanyan-Gandilyan, N.; Sultana, N.; Tsooj, S.; Urgamal, M.; Valles, J.; van Velzen, R.; Pokorny, L.
10.1101/2024.10.17.618884 — genomics — Posted on 2024-10-20
2126 Darwin's Naturalization Conundrum explained by gradients of environmental stress and disturbance
Galman, A.; Alexander, J. M.; Cavieres, L. A.; Daehler, C. C.; Seipel, T.; Winter, M.; Andersen, K. M.; Lembrechts, J.; Aschero, V.; Sierra, J. R. A.; Barros, A.; Buhaly, M.; Backes, A. R.; Dar, P. A.; Fuentes-Lillo, E.; Jimenez, A.; Kuffer, C.; Larson, C. D.; Mihoc, M.; Milbau, A.; Morgan, J. W.; McDougall, K.; Mullerova, J.; Naylor, B.; Nunez, M. A.; Mederos, M. A. P.; Pauchard, A.; Rew, L. J.; Reshi, Z. A.; Sandoya, V.; Shah, M. A.; Shannon, J. M.; Walsh, N.; Valencia, G.; Vorstenbosch, T.; Wright, G.; Zong, S.; Haider, S.
10.1101/2024.10.17.618817 — ecology — Posted on 2024-10-20
2131 Evaluating the Biocontrol Potential of Pythium oligandrum and Serratia proteamaculans in Controlling Phytophthora plurivora in European beech (Fagus sylvatica)
Kelbessa, B. G.; Samuelsson, A.; Ghadamgahi, F.; Witzell, J.; Whisson, S.; Ortiz, R.; Grenville-Briggs, L.; Vetukuri, R. R.
10.1101/2024.10.17.618890 — pathology — Posted on 2024-10-20
2133 ENACT: End-to-End Analysis of Visium High Definition (HD) Data
Kamel, M.; Song, Y.; Solbas, A.; Villordo, S.; Sarangi, A.; Senin, P.; Mathew, S.; Ayestas, L. C.; Wang, S.; Classe, M.; Bar-Joseph, Z.; Planas, A. P.
10.1101/2024.10.17.618905 — bioinformatics — Posted on 2024-10-20
2136 Measurement and classification of bold-shy behaviours in medaka fish
Pierotti, S.; Brettell, I.; Fitzgerald, T.; Herder, C.; Aadepu, N.; Pylatiuk, C.; Wittbrodt, J.; Birney, E.; Loosli, F.
10.1101/2024.10.18.618696 — bioinformatics — Posted on 2024-10-20
2137 Bio-medical Big Data Operating System (Bio-OS): An Integrated Data Mining Environment for Data Intensive Scientific Research
Liu, J.; Yang, L.; Xiao, Q.; Li, Z.; Chen, J.; Chen, Z.; Zhou, J.; Wan, X.; Tsung-Hui Chang, T.-H.; Zhang, X.; Li, Y.
10.1101/2024.10.17.612997 — bioinformatics — Posted on 2024-10-20
2139 Metabolic analysis of sarcopenic muscle identifies positive modulators of longevity and health span in C. elegans
Jonk, S.; Nicol, A.; Chrysostomou, V.; Lardner, E.; Yu, S.-C.; Stalhammar, G.; Crowston, J.; Tribble, J.; Swoboda, P.; Williams, P. A.
10.1101/2024.10.19.616468 — cell biology — Posted on 2024-10-20
2140 Enrichment of spermatogonial stem cells and staging of the testis cycle in a dasyurid marsupial, the fat-tailed dunnart
Tarulli, G. A.; Tatt, P. R.; Howlett, R. B.; Ord, S.; Shapiro, B. A.; Frankenberg, S. R.; Pask, A. J.
10.1101/2024.10.19.616824 — cell biology — Posted on 2024-10-20
2141 Semi-automated monitoring of longitudinal microbial metabolic dynamics: A study case for lignin degradation
Guimaraes Ferreira, J. V.; Arini, G. S.; da Rosa-Garzon, N. G.; Casanova Turatti, I. C.; Borelli, T. C.; Tsuji, H. M. Y. d. O.; Cabral, H.; da Silva, R. R.
10.1101/2024.10.18.619076 — microbiology — Posted on 2024-10-20
2142 Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1
Yu, D.; Jain, S.; Wangzhou, A.; De Florencio, S.; Zhu, B.; Kim, J.; Choi, J.; Paredes, M.; Nowakowski, T. J.; Huang, E. J.; Piao, X.
10.1101/2024.10.19.619180 — neuroscience — Posted on 2024-10-20
2144 Sugarcane yellow leaf virus impairs the transcriptomic defense responses of sugarcane to its new aphid vector Melanaphis sorghi
Pimenta, R. J. G.; Aono, A. H.; Sforca, D. A.; Melloni, N. G.; Goncalves, M. C.; Pinto, L. R.; de Souza, A. P.
10.1101/2024.10.17.618922 — plant biology — Posted on 2024-10-20
2147 Establishment & Characterization of a Non-Adherent Insect Cell Line for Cultivated Meat
Letcher, S. M.; Calkins, O. P.; Clausi, H. J.; McCreary, A.; Trimmer, B. A.; Kaplan, D. L.
10.1101/2024.10.18.618906 — bioengineering — Posted on 2024-10-20
2152 Mechanism of Interaction Between the Transactivation Domain of N-MYC and the DNA-Binding Surface of TFIIIC5
Leen, E.; Yeoh, S.; Sahak, E.; Mitchell, E.; Wildsmith, G.; Batchelor, M.; Calabrese, A. N.; Büchel, G.; Bayliss, R.
10.1101/2024.10.19.619198 — molecular biology — Posted on 2024-10-20
2153 Protective human monoclonal antibodies that target the Type III Secretion System of Pseudomonas aeruginosa inhibit translocon function
Desveaux, J.-M.; Faudry, E.; Contreras-Martel, C.; Cretin, F.; Dergan-Dylon, L. S.; Amen, A.; Bally, I.; Tardivy-Casemajor, V.; Chenavier, F.; Fouquenet, D.; Caspar, Y.; Attree, I.; Dessen, A.; Poignard, P.
10.1101/2024.10.19.619220 — microbiology — Posted on 2024-10-20
2162 Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea
Rados, T.; Leland, O.; Escudeiro, P.; Mallon, J.; Andre, K.; Caspy, I.; vonKugelgen, A.; Stolovicki, E.; Nguyen, S.; Patop, I.; Rangel, L. T.; Kadener, S.; Renner, L.; Thiel, V.; Soen, Y.; Bharat, T.; Alva, V.; Bisson, A.
10.1101/2024.10.19.619234 — cell biology — Posted on 2024-10-19
2164 Phosphorylation-dependent tuning of mRNA deadenylation rates
Stowell, J. A.; Yu, C. W.; Chen, Z.; Lee, G.; Morgan, T.; Sinn, L.; Agnello, S.; O'Reilly, F.; Rappsilber, J.; Freund, S. M.; Passmore, L. A.
10.1101/2024.10.18.618793 — molecular biology — Posted on 2024-10-19
2166 Impact of methicillin resistance on virulence factor expression in 1 Staphylococcus aureus: Insights from gene expression profiling
Gharsallah, C.; Ferjani, A.; Ghariani, M.; Ferjani, S.; Kanzari, L.; Rehaiem, A.; Fakhfakh, A.; Boutiba Ben Boubaker, I.
10.1101/2024.10.19.619075 — microbiology — Posted on 2024-10-19
2168 An envelope stress response governs long-chain fatty acid metabolism via a small RNA to maintain redox homeostasis in Escherichia coli
Shrivastava, M.; Kaur, M.; Luke, L. M.; Kakkar, R. A.; Roy, D.; Singla, S.; Sharma, V.; Sharma, G.; Chaba, R.
10.1101/2024.10.18.618624 — microbiology — Posted on 2024-10-19
2171 Amino acid competition shapes Acinetobacter baumannii gut carriage
Ren, X.; Clark, R. M.; Bansah, D. A.; Varner, E. N.; Tiffany, C. R.; Jaswal, K.; Geary, J. H.; Todd, O. A.; Winkelman, J. D.; Friedman, E. S.; Zemel, B. S.; Wu, G. D.; Zackular, J. P.; DePas, W. H.; Behnsen, J.; Palmer, L. D.
10.1101/2024.10.19.619093 — microbiology — Posted on 2024-10-19
2172 Packaged delivery of CRISPR-Cas9 ribonucleoproteins accelerates genome editing
Karp, H.; Zoltek, M.; Wasko, K.; Vazquez, A. L.; Brim, J.; Ngo, W.; Schepartz, A.; Doudna, J. A.
10.1101/2024.10.18.619117 — bioengineering — Posted on 2024-10-19
2173 High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA Aptamers and Deep Sequencing
Khan, E. A.; Rückert-Reed, C.; Dahiya, G. S.; Tietze, L.; Fages-Lartaud, M.; Busche, T.; Kalinowski, J.; Shingler, V.; Lale, R.
10.1101/2024.10.18.619134 — biochemistry — Posted on 2024-10-19
2174 Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage
Lago-Maciel, A.; Soares, J. C.; Zarzycki, J.; Buchanan, C. J.; Reif-Trauttmansdorff, T.; Schmidt, F. V.; Lometto, S.; Paczia, N.; Schuller, J. M.; Hansen, D. F.; Heller, G. T.; Prinz, S.; Hochberg, G. K. A.; Pierik, A. J.; Rebelein, J. G.
10.1101/2024.10.19.619033 — biochemistry — Posted on 2024-10-19
2176 Drp1-mediated mitochondrial fission protects macrophages from mtDNA/ZBP1-mediated sterile inflammation and inhibits post-infarct cardiac remodeling
Kondo, Y.; Koga, J.-i.; Orkhonselenge, N.; Wang, D.-Z.; Hasuzawa, N.; Katsuki, S.; Matoba, T.; Nishimura, Y.; Nomura, M.; Kataoka, M.
10.1101/2024.10.18.619173 — biochemistry — Posted on 2024-10-19
2180 Non-lytic spread of poliovirus requires the nonstructural protein 3CD
Aponte-Diaz, D.; Harris, J. M.; Kang, T. E.; Korboukh, V.; Sotoudegan, M. S.; Gray, J. L.; Yennawar, N. H.; Moustafa, I. M.; Macadam, A.; Cameron, C. E.
10.1101/2024.10.18.619132 — microbiology — Posted on 2024-10-19
2181 Discovery of broad-spectrum bacterial polyamine detoxification inhibitors as potential antivirulence agents and antibiotic adjuvants
Moulding, P. B.; Flannagan, R. S.; Wong, J.; Soliman, A. M.; Elhenawy, W.; Heinrichs, D. E.; El-Halfawy, O. M.
10.1101/2024.10.18.618978 — microbiology — Posted on 2024-10-19
2186 Regulating biocondensates within synthetic cells via segregative phase separation
Chen, C.; Love, C. M.; Carnahan, C. F.; Ganar, K. A.; Parikh, A. N.; Deshpande, S.
10.1101/2024.10.18.619037 — synthetic biology — Posted on 2024-10-19
2188 Localized synthesis of molecular chaperones sustains neuronal proteostasis
Alecki, C.; Rizwan, J.; Le, P.; Jacob-Tomas, S.; Fernandez-Comaduran, M.; Verbrugghe, M.; Xu, J. S. M.; Minotti, S.; Lynch, J.; Biswas, J.; Wu, T.; Durham, H.; Yeo, G. W.; Vera, M.
10.1101/2023.10.03.560761 — molecular biology — Posted on 2024-10-19
2189 Art's Hidden Topology: A window into human perception
Dmitruk, E.; Bajno, B.; Dreszer, J.; Bałaj, B.; Ratajczak, E.; Hajnowski, M.; Janik, R.; Kus, M.; Kadir, S. N.; Rogala, J.
10.1101/2024.10.16.618741 — neuroscience — Posted on 2024-10-19
2190 Extracellular matrix remodeling during aging aligns with synapse, microglia, and cognitive status
Gray, D. T.; Guitierrez, A.; Jami-Alahmadi, Y.; Pandey, V.; Pan, L.; Zhang, Y. T.; Wohlschlegel, J. A.; McDevitt, R.; De Biase, L. M.
10.1101/2024.01.04.574215 — neuroscience — Posted on 2024-10-19
2196 A novel motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin
Bradburn, D. A.; Reis, J. C.; Qayyum, S.; Viennet, T.; Arthanari, H.; Cyert, M. S.
10.1101/2024.05.12.593783 — biochemistry — Posted on 2024-10-19
2198 An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m6A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction
Guo, Z.; Lu, L.; Sarkar, A. K.; Dao, L.; Liu, Y.; Ma, C.; Thwin, P. H.; Chang, X.; Yoshida, G.; Li, A.; Wang, C.; Westerkamp, G.; Schmitt, L.; Chelsey, M.; Stephanie, M.; Zhao, Y.; Liu, Y.; Wang, X.; Zhu, L.-Q.; Liu, D.; Tchieu, J.; Miyakoshi, M.; Zhu, H.; Gross, C.; Pedapati, E.; Salomonis, N.; Erickson, C.
10.1101/2024.10.14.618205 — neuroscience — Posted on 2024-10-19
2200 A new phylogenetic framework for the genus Kalanchoe (Crassulaceae) and implications for infrageneric classification
Rodewald, S. E.; Klein, D.-P.; Shtein, R.; Smith, G. F.; Joyce, E.; Morales-Briones, D. F.; Bernhard, S.; Letsara, R.; Mertes, H.; Huehn, P.; Kadereit, G.
10.1101/2024.10.17.618389 — evolutionary biology — Posted on 2024-10-19
2202 Mechanical control of germ cell specification in Arabidopsis anthers
Liu, C.; Shi, H.; Han, Y.; Wang, P.; Li, K.; Zhang, Z.; Liu, J.; Zheng, Y.; Li, L.; Lin, L.; Liang, C.; Qin, B.; Han, H.; Bai, S.; Liu, X.; Chen, W.; Zhao, F.
10.1101/2024.10.17.618875 — developmental biology — Posted on 2024-10-19
2203 Zebrahub-Multiome: Uncovering Gene Regulatory Network Dynamics During Zebrafish Embryogenesis
Kim, Y. J.; VijayKumar, S.; Iovino, B.; Granados, A.; Ancheta, S.; Zhao, X.; Awayan, K.; Seng, A.; Borja, M.; Paul, S.; Mekonen, H.; Arjyal, R.; Detweiler, A.; Senbabaoglu, Y.; Gomez-Sjoberg, R.; Neff, N.; Lange, M.; Royer, L. A.
10.1101/2024.10.18.618987 — developmental biology — Posted on 2024-10-19
2204 Loss of Bicra/Gltscr1 leads to a defect in fetal liver macrophages responsible for erythrocyte maturation in mice.
Sood, S.; Alpsoy, A.; Jiao, G.; Dhiman, A.; King, C. S.; Conjelko, G.; Hallett, J.; Utturkar, S.; Hutchcroft, J.; Dykhuizen, E.
10.1101/2024.10.17.618940 — developmental biology — Posted on 2024-10-19
2205 New assessment of teichoic acids in the cell envelope of Streptococcus pneumoniae
Mai, N.; Bauda, E.; Boyat, C.; Laguri, C.; Freton, C.; Chouquet, A.; Gallet, B.; Baudoin, M.; Wong, Y.-S.; Grangeasse, C.; Moriscot, C.; Durmort, C.; Zapun, A.; Morlot, C.
10.1101/2024.10.18.619035 — microbiology — Posted on 2024-10-19
2206 The genital tract microbiota of IVF patients and oocyte donors: a comparative analysis
Haahr, T.; Humaidan, P.; Bernabeu, A.; Lledo, B.; Plummer, E. L.; Bradshaw, C. S.; Ingham, A. C.; Jensen, J. S.
10.1101/2024.10.18.619104 — microbiology — Posted on 2024-10-19
2207 Federated deep learning enables cancer subtyping by proteomics
Cai, Z.; Boys, E. L.; Noor, Z.; Aref, A.; Xavier, D.; Lucas, N.; Williams, S. G.; Koh, J. M. S.; Poulos, R. C.; Wu, Y.; Dausmann, M.; MacKenzie, K. L.; Aguilar-Mahecha, A.; Armengol, C.; Barranco, M. M.; Basik, M.; Bowman, E. D.; Clifton-Bligh, R. J.; Connolly, E. A.; Cooper, W. A.; Dalal, B.; DeFazio, A.; Filipits, M.; Flynn, P. J.; Graham, J. D.; George, J.; Gill, A. J.; Gnant, M.; Habib, R.; Harris, C. C.; Harvey, K.; Horvath, L. G.; Jackson, C.; Kohonen-Corish, M. R. J.; Lim, E.; Liu, J.; Long, G.; Lord, R. V.; Mann, G. J.; McCaughan, G. W.; Morgan, L.; Murphy, L. C.; Nagabushan, S.; Nagri
10.1101/2024.10.16.618763 — cancer biology — Posted on 2024-10-19
2212 A dendritic substrate for temporal diversity of cortical inhibition
Morabito, A.; Zerlaut, Y.; Dhanasobhon, D.; Berthaux, E.; Tzilivaki, A.; Moneron, G.; Cathala, L.; Poirazi, P.; Bacci, A.; DiGregorio, D.; Lourenco, J.; Rebola, N.
10.1101/2024.07.09.602783 — neuroscience — Posted on 2024-10-19
2213 Transcriptional reactivation of the tRNASer/tRNATyr gene cluster in Arabidopsis thaliana root tip (V2)
Hummel, G.; Kumari, P.; Hua, C.; Wang, L.; Mai, Y.-X.; Wang, N.; Shala, N.; Kaya, E. C.; Molinier, J.; Wang, J.-W.; Liu, C.
10.1101/2023.09.27.559738 — plant biology — Posted on 2024-10-19
2216 TORC2-regulated sterol redistribution mediates recovery from membrane perturbation by small amphipathic molecules.
Tettamanti, M. G.; Nowak, P.; Kusmider, B.; Kefauver, J. M.; Mercier, V.; Roux, A.; Loewith, R.
10.1101/2024.10.18.618785 — cell biology — Posted on 2024-10-19
2217 Functional differentiation of Human Dental Pulp Stem Cells into neuron-like cells exhibiting electrophysiological activity
Pardo-Rodriguez, B.; Baraibar, A. M.; Manero-Roig, I.; Luzuriaga, J.; Salvador-Moya, J.; Polo, Y.; Basanta-Torres, R.; Unda, F.; Mato, S.; Ibarretxe, G.; Pineda, J. R.
10.1101/2024.10.18.619039 — cell biology — Posted on 2024-10-19
2218 Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC-derived neurons
Kadam, V.; Wacker, M.; Oeckl, P.; Korneck, M.; Dannenmann, B.; Skokowa, J.; Hauser, S.; Otto, M.; Synofzik, M.; Mengel, D.
10.1101/2024.10.14.618132 — neuroscience — Posted on 2024-10-19
2225 Monitoring lysosomal catabolism: a sensitive probe for assessing targeted lysosomal degradation of extracellular proteins
Holly, R. W.; Hu, Y.-Z.; Beena Valsan, V.; Kougentakis, C.; Petronikolou, N.; Chen, T.; Li, D.; Chen, A.; Rank, S.; Doran, K. H.; Turtle, E.; Langsdorf, C.; Shurtleff, M. J.
10.1101/2024.10.18.619124 — cell biology — Posted on 2024-10-19
2227 TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling
Kim, D.; Bhargava, R.; Wang, S.-C.; Lee, D.; Patel, R.; Oh, S.; Bowman, R. W.; Na, C. H.; O'Sullivan, R. J.; Miller, K. M.
10.1101/2024.10.18.618947 — cell biology — Posted on 2024-10-19
2229 Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability
Talianidis, I.; Botskaris, D.; Deligiannis, I.; Peraki, I.; Kontaki, H.; Stagaki, M.; Lavigne, M.; Martinez-Jimenez, C. P.
10.1101/2024.10.18.619079 — cell biology — Posted on 2024-10-19
2231 Jamaican fruit bats (Artibeus jamaicensis) competence for Ebola virus but not Marburg virus is driven by intrinsic differences in viral entry and IFN-I signaling antagonism.
Van Tol, S.; Port, J.; Fischer, R.; Gallogly, S.; Bushmaker, T.; Griffin, A.; Schulz, J. E.; Carmody, A. B.; Myers, L.; Crowley, D.; Falvo, C.; Riopelle, J.; Wickenhagen, A.; Clancy, C.; Lovaglio, J.; Shaia, C.; Saturday, G.; Prado-Smith, J.; Hr, Y.; Lack, J.; Martens, C.; Anzick, S.; Kendall, L.; Schountz, T.; Plowright, R.; Marzi, A.; Munster, V.
10.1101/2024.10.17.618736 — immunology — Posted on 2024-10-19
2232 White Matter Microstructural Alterations in Autism Localized with Bundle Analytics
Kim, G. S.; Chandio, B. Q.; Benavidez, S. M.; Thompson, P. M.; Lawrence, K. E.
10.1101/2024.10.16.618731 — neuroscience — Posted on 2024-10-19
2235 Cell type-focused compound screen in human organoids reveals CK1 and MAPK11 inhibition protects cone photoreceptors from death
Spirig, S. E.; Arteaga-Moreta, V. J.; Raics, Z.; Posada-Cespedes, S.; Chreng, S.; Galuba, O.; Galuba, I.; Claerr, I.; Renner, S.; Utz, L.; Kleindienst, T.; Volak, A.; Imbach, J.; Malysheva, S.; Siwicki, R. A.; Hahaut, V.; Hou, Y.; Picelli, S.; Cattaneo, M.; Jüttner, J.; Cowan, C. S.; Duckely, M.; Baeschlin, D. K.; Renner, M.; Unterreiner, V.; Roska, B.
10.1101/2023.10.09.561525 — neuroscience — Posted on 2024-10-19
2237 Oral vancomycin treatment alters levels of indole derivatives and secondary bile acids modulating the expression of mTOR pathway genes in astrocytes during EAE
Bianchimano, P.; Leone, P.; Smith, E.; Gutierrez-Vazquez, C.; Wind-andersen, E.; Bongers, G.; Cristancho, S.; Weiner, H.; Clemente, J. C.; Tankou, S.
10.1101/2024.06.14.599110 — neuroscience — Posted on 2024-10-19
2241 Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering
De, S.; Zhou, M.; Brown, Z. P.; Burton-Smith, R. N.; Hashem, Y.; Pestova, T.; Hellen, C. U. T.; Frank, J.
10.1101/2024.10.11.617640 — biophysics — Posted on 2024-10-19
2244 Glioblastoma Treatment by Systemic Actinium-225 alpha-particle Dendrimer-radioconjugates is Improved by Chemotherapy
Nair, R. R.; Sarkar, A.; Hariharan, P.; Gabrielson, K. L.; Wu, T.; Liu, C.; Sharma, A.; Liyanage, W.; Bhujwalla, Z. M.; Vidaver, M.-F. P.; Kannan, R. M.; Sofou, S.
10.1101/2024.10.17.618960 — bioengineering — Posted on 2024-10-19
2245 CelFDrive: Artificial Intelligence assisted microscopy for automated detection of rare events
Brooks, S.; Toral-Perez, S.; Corcoran, D. S.; Kilborn, K.; Bodensteiner, B.; Baumann, H.; Burroughs, N. J.; McAinsh, A. D.; Bretschneider, T.
10.1101/2024.10.17.618897 — bioengineering — Posted on 2024-10-19
2248 Comparative Analysis of Lysine-Specific Peptidases for Optimizing Proteomics Workflows
van der Hoeven, L. R.; Lechner, M.; Hernandez-Rollan, C.; Batth, T. S.; Olsen, J. V.
10.1101/2024.10.18.619105 — biochemistry — Posted on 2024-10-18
2250 Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration
Chen, C.; Gao, T.-Y.; Yi, H.-W.; Zhang, Y.; Wang, T.; Lou, Z.-L.; Wei, T.-F.; Lu, Y.-B.; Li, T.; Tang, C.; Zhang, W.-P.
10.1101/2024.10.18.619025 — biochemistry — Posted on 2024-10-19
2252 Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics
Rankovic, Z.; Wu, Q.; Yang, J.; Nishiguchi, G.; Daub, H.; Shashikadze, B.; Machata, S.; Graef, T.; Schwalb, B.; Bartoschek, D.; Ohmayer, U.; Bednarz, A. H.; McGowan, K.; Shi, Z.; Price, J.; Mayasundari, A.; Yang, L.; Demichev, V.; Steger, M.
10.1101/2024.10.18.618633 — biochemistry — Posted on 2024-10-19
2253 Dissecting RNA Selectivity Mediated by Tandem RNA-Binding Domains
Harris, S. E.; Hu, Y.; Bridges, K.; Guzman, B. B.; Cavazos, F. F.; Martyr, J. M.; Aleman, M. M.; Murn, J.; Dominguez, D.
10.1101/2024.10.17.618930 — biochemistry — Posted on 2024-10-19
2255 A super-pangenome for cultivated citrus reveals evolutive features during the allopatric phase of their reticulate evolution
Droc, G.; Giraud, D.; Belser, C.; Labadie, K.; Duprat, S.; Cruaud, C.; Istace, B.; Dos Santos Menezes, F.; Curk, F.; Costantino, G.; Soriano, A.; Mournet, P.; Dereeper, A.; Miranda, M.; Marchi, E.; Santoni, S.; Santana, R.; Sidibe-Bocs, S.; Luro, F.; Choisne, N.; Maumus, F.; Hufnagel, B.; Micheli, F.; Wincker, P.; Aury, J.-M.; Lemainque, A.; Ollitrault, P.
10.1101/2024.10.17.618847 — genomics — Posted on 2024-10-18
2256 Context-dependent epigenome rewiring during neuronal differentiation
Manelli, V.; Diwakar, J.; Beskardes, S.; Alonso-Gil, D.; Forne, I.; Chong, F.; Imhof, A.; Bonev, B.
10.1101/2024.10.18.618996 — genomics — Posted on 2024-10-18
2258 RatXcan: A framework for cross-species integration of genome-wide association and gene expression data
Santhanam, N.; Sanchez-Roige, S.; Mi, S.; Liang, Y.; Chitre, A.; Munro, D.; Chen, D.; Nyasimi, F.; Gao, J.; George, A. M.; Gileta, A. F.; Holl, K.; Hughson, A.; King, C. P.; Lamparelli, A. C.; Martin, C. D.; Martinez, A. G.; St. Pierre, C. L.; Tripi, J.; Wang, T.; Chen, H.; Flagel, S.; Ishiwari, K.; Meyer, P.; Polesskaya, O.; Saba, L.; Woods, L. S.; Palmer, A. A.; Im, H. K.
10.1101/2022.06.03.494719 — genomics — Posted on 2024-10-19
2259 Novel nanopore sequencing method for determining Human Papillomavirus integrations in tumors without the need for whole genome sequencing
Parida, P.; Mukherjee, N.; Singh, A.; Lewis, S.; Sharan, K.; Mallya, S.; Singh, A.; Rao, M.; Higginson, D. S.; Sabarinathan, R.; Damerla, R. R.
10.1101/2024.10.17.618842 — genomics — Posted on 2024-10-19
2260 Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair
McDaniel, J. H.; Patel, V.; Olson, N. D.; He, H.-J.; He, Z.; Cole, K. D.; Schmitt, A.; Sikkink, K.; Sedlazeck, F.; Doddapaneni, H.; Jhangiani, S. N.; Muzny, D. M.; Gingras, M.-C.; Mehta, H.; Paulin, L. F.; Hastie, A. R.; Yu, H.-C.; Weigman, V.; Rojas, A.; Kennedy, K.; Remington, J.; Gonzalez, I.; Sudkamp, M.; Wiseman, K.; Lajoie, B. R.; Levy, S.; Jain, M.; Akeson, S.; Narzisi, G.; Steinsnyder, Z.; Reeves, C.; Shelton, J.; Kingan, S. B.; Lambert, C.; Bayabyan, P.; Wenger, A. M.; McLaughlin, I. J.; Adamson, A.; Kingsley, C.; Wescott, M.; Kim, Y.; Paten, B.; Park, J.; Violich, I.; Miga, K. H.; Ga
10.1101/2024.09.18.613544 — genomics — Posted on 2024-10-19
2263 Advanced deep-tissue imaging and manipulation enabled by biliverdin reductase knockout.
Kasatkina, L.; Ma, C.; Sheng, H.; Lowerison, M.; Menozzi, L.; Baloban, M.; Tang, Y.; Xu, Y.; Humayun, L.; Vu, T.; Song, P.; Yao, J.; Verkhusha, V.
10.1101/2024.10.18.619161 — cell biology — Posted on 2024-10-18
2264 Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption
Yong, J.; Villalta, J. E.; Vu, N.; Kukurugya, M. A.; Olsson, N.; Lopez, M. P.; Lazzari-Dean, J. R.; Hake, K.; McAllister, F.; Bennett, B. D.; Jan, C. H.
10.1101/2022.11.23.517579 — cell biology — Posted on 2024-10-18
2266 Epigenetic modulation of RIPK3 by Transglutaminase 2-dependent serotonylation of H3K4me3 affects necroptosis
Vecchio, A.; Colasuonno, F.; Bellanca, V.; Pitolli, C.; Occhigrossi, L.; Ciccarone, F.; D'Eletto, M.; Di Sano, F.; Pagliarini, V.; Sette, C.; Piacentini, M.; Rossin, F.
10.1101/2024.10.18.619049 — cell biology — Posted on 2024-10-19
2268 Systemic effects of cystic fibrosis transmembrane conductance regulator (CFTR) modulators on the blood proteome
Fentker, K.; Kirchner, M.; Ziehm, M.; Niquet, S.; Popp, O.; Duerr, J.; Schaupp, L.; Roehmel, J.; Thee, S.; Haemmerling, S.; Sommerburg, O.; Stahl, M.; Graeber, S. Y.; Mall, M. A.; Mertins, P.
10.1101/2024.10.18.619058 — molecular biology — Posted on 2024-10-18
2270 Iron-sensitive RNA regulation by poly C binding proteins
Forbes, K.; Goda, G. A.; Eramo, G. A.; Breen, C.; Porter, D. F.; Khavari, P. A.; Dominguez, D.; Aleman, M. M.
10.1101/2024.10.17.618301 — molecular biology — Posted on 2024-10-18
2277 Qualitative EEG abnormalities signal a shift towards inhibition-dominated brain networks. Results from the EU-AIMS LEAP studies
Juarez-Martinez, E. L.; Avramiea, A.-E.; Garces, P.; Hipp, J. F.; Poil, S.-S.; Diachenko, M.; Mansvelder, H.; Jones, E. J.; Mason, L.; Murphy, D.; Loth, E.; Oakley, B.; Charman, T.; Banaschewski, T.; Oranje, B.; Buitelaar, J.; Bruining, H.; Linkenkaer-Hansen, K.
10.1101/2024.09.19.613847 — neuroscience — Posted on 2024-10-18
2278 Intrinsic dynamic shapes responses to external stimulation in the human brain
Nentwich, M.; Leszczynski, M.; Schroeder, C. E.; Bickel, S.; Parra, L. C.
10.1101/2024.08.05.606665 — neuroscience — Posted on 2024-10-18
2279 Pre-stimulus beta power mediates explicit and implicit perceptual biases in distinct cortical areas
Forster, C.; Stephani, T.; Grund, M.; Panagoulas, E.; Al, E.; Hofmann, S. M.; Nikulin, V. V.; Villringer, A.
10.1101/2024.06.12.598458 — neuroscience — Posted on 2024-10-18
2280 Art's Hidden Topology: A window into human perception
Dmitruk, E.; Bajno, B.; Dreszer, J.; Bałaj, B.; Ratajczak, E.; Hajnowski, M.; Janik, R.; Kus, M.; Kadir, S. N.; Rogala, J.
10.1101/2024.10.16.618741 — neuroscience — Posted on 2024-10-19
2281 Functional Localization of the Human Auditory and Visual Thalamus Using a Thalamic Localizer Functional Magnetic Resonance Imaging Task
Williams, J. C.; Tubiolo, P. N.; Zheng, Z. J.; Silver-Frankel, E. B.; Pham, D. T.; Haubold, N. K.; Abeykoon, S. K.; Abi-Dargham, A.; Horga, G.; Van Snellenberg, J. X.
10.1101/2024.04.28.591516 — neuroscience — Posted on 2024-10-19
2282 Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates
Totty, M. S.; Cervera-Juanes, R.; Bach, S. V.; Ben Ameur, L.; Valentine, M. R.; Simons, E.; Romac, M. D.; Trinh, H.; Henderson, K.; Del Rosario, I.; Tippani, M.; Miller, R. A.; Kleinman, J. E.; Cerceo Page, S.; Saunders, A.; Hyde, T. M.; Martinowich, K.; Hicks, S. C.; Costa, V. D.
10.1101/2024.10.18.618721 — neuroscience — Posted on 2024-10-19
2285 Creating a biomedical knowledge base by addressing GPT inaccurate responses and benchmarking context
Darnell, S. S.; Prins, J. P.; Suh, E.; Huang, P.; Williams, R. W.; Overall, R.; Chen, H.; Garrison, E.; Guarracino, A.; Villani, F.; Muli, P.; Ashbrook, D. G.; Colonna, V.; Batten, C.; Sen, S.; Muriithi, F. M.; Yousefi, S.; Nijveen, H.; Lisso, F.; Isaac, A.; Kabui, A.; Kilungi, M. B.; Kibet, A.; Umar, M.; Muhia, B.
10.1101/2024.10.16.618663 — scientific communication and education — Posted on 2024-10-18
2286 Impact of mutations in the HEADING DATE 1 gene on transcription and cell wall composition of rice
Biancucci, M.; Chirivi, D.; Baldini, A.; Badenhorst, E.; Dobetti, F.; Khahani, B.; Formentin, E.; Eguen, T.; Turck, F. K.; Moore, J. P.; Tavakol, E.; Wenkel, S.; Lo Schiavo, F. L.; Ezquer, I.; Brambilla, V.; Horner, D. S.; Chiara, M.; Perrella, G.; Betti, C.; Fornara, F.
10.1101/2024.10.16.618758 — plant biology — Posted on 2024-10-18
2290 PD-L1+ Neutrophils mediate Susceptibility during Systemic Inflammatory Response in Non-Alcoholic Fatty Liver Disease
Barros, C. d. C. O.; Kanashiro, A.; da Silva, G. V. L.; Cebinelli, G. C. M.; Leiria, L.; Cunha, T. M.; Alves-Filho, J. C.; Cunha, F. Q.
10.1101/2024.10.16.618651 — immunology — Posted on 2024-10-18
2293 scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer
Huang, C.; Liu, Z.; Guo, Y.; Wang, W.; Yuan, Z.; Guan, Y.; Pan, D.; Hu, Z.; Sun, L.; Fu, Z.; Bian, S.
10.1101/2024.06.24.600356 — cancer biology — Posted on 2024-10-18
2296 Octahedral small virus-like particles of dengue virus type 2
Johnson, A.; Dodes Traian, M.; Walsh, R. M.; Jenni, S.; Harrison, S. C.
10.1101/2024.10.17.618815 — microbiology — Posted on 2024-10-18
2297 Prediction of pathological subthalamic nucleus beta burst occurrence in Parkinson's disease
Abdi-Sargezeh, B.; Shirani, S.; Sharma, A.; Green, A.; Akram, H.; Zrinzo, L.; Limousin, P.; Foltynie, T.; Denison, T.; Tan, H.; Litvak, V.; Oswal, A.
10.1101/2024.05.09.593398 — neuroscience — Posted on 2024-10-18
2300 Phosphorylation Toggles the SARS-CoV-2 Nucleocapsid Protein Between Two Membrane-Associated Condensate States
Favetta, B.; Wang, H.; Cubuk, J.; Barai, M.; Ramirez, C.; Gormley, A. J.; Murthy, S.; Soranno, A.; Shi, Z.; Schuster, B. S.
10.1101/2024.10.17.618867 — biophysics — Posted on 2024-10-18
2302 Raman flow cytometry using time delay integration
Lindley, M.; Kubo, T.; Devineau, S.; Li, M.; Qiao, J.; Yashiro, T.; Iwanaga, S.; Moro, K.; Fujita, K.
10.1101/2024.10.17.617595 — biophysics — Posted on 2024-10-18
2304 Candidate Denisovan fossils identified through gene regulatory phenotyping
Mishol, N.; Herzlinger, G.; Rak, Y.; Smilansky, U.; Carmel, L.; Gokhman, D.
10.1101/2024.04.18.590145 — genetics — Posted on 2024-10-18
2305 Charting the landscape of cytoskeletal diversity in microbial eukaryotes
Mikus, F.; Ramos, A. R.; Shah, H.; Olivetta, M.; Borgers, S.; Hellgoth, J.; Saint-Donat, C.; Araujo, M.; Bhickta, C.; Cherek, P.; Bilbao, J.; Txurruka, E.; Leisch, N.; Schwab, Y.; Husnik, F.; Seoane, S.; Probert, I.; Guichard, P.; Hamel, V.; Dey, G.; Dudin, O.
10.1101/2024.10.18.618984 — cell biology — Posted on 2024-10-18
2307 Nanomaterials trigger functional responses in primary human immune cells
Mittelheisser, V.; Lefebvre, O.; Banerjee, M.; Ghosh, S.; Dupas, A.; Diringer, M.-C.; Blumberger, J.; Bochler, L.; Harlepp, S.; Larnicol, A.; Pichot, A.; Stemmelen, T.; Molitor, A.; Moritz, C.; Carapito, C.; Carapito, R.; Charbonniere, L.; Lux, F.; Tillement, O.; Goetz, J. G.; Detappe, A.
10.1101/2024.10.17.618911 — immunology — Posted on 2024-10-18
2308 B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
Cho, S. H.; Jones, M. A.; Meyer, K.; Anderson, D. M.; Chetyrkin, S.; Calcutt, M. W.; Caprioli, R. M.; Semekovich, C. F.; Boothby, M. R.
10.1101/2024.10.17.618760 — immunology — Posted on 2024-10-18
2310 Simulation Insights on the Compound Action Potential in Multifascicular Nerves
Tharayil, J. J.; Zinno, C.; Agnesi, F.; Lloyd, B.; Farcito, S.; Cassara, A.; Kuster, N.; Reimann, M. W.; Micera, S.; Neufeld, E.
10.1101/2024.10.16.618681 — neuroscience — Posted on 2024-10-18
2314 Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics
Avraham-Davidi, I.; Mages, S.; Klughammer, J.; Moriel, N.; Imada, S.; Hofree, M.; Murray, E.; Chen, J.; Pelka, K.; Mehta, A.; Boland, G. M.; Delorey, T. M.; Caplan, L.; Dionne, D.; Strasser, R.; Lalakova, J.; Niesnerova, A.; Xu, H.; Rouault, M.; Tirosh, I.; Hacohen, N.; Chen, F.; Yilmaz, O. H.; Roper, J.; Rozenblatt-Rosen, O.; Nitzan, M.; Regev, A.
10.1101/2022.10.02.508492 — cancer biology — Posted on 2024-10-18
2315 SSTR2-targeted theranostics in hepatocellular carcinoma
Momeny, M.; AghaAmiri, S.; Vargas, S. H.; Acidi, B.; Ghosh, S. C.; Bateman, T.; Adams, J.; Khalaj, V.; Kaseb, A. O.; Cao, H. S. T.; Azhdarinia, A.
10.1101/2024.10.16.618740 — cancer biology — Posted on 2024-10-18
2317 A microfluidic platform for extraction and analysis of bacterial genomic DNA
Joesaar, A.; Holub, M.; Lutze, L.; Emanuele, M.; Kerssemakers, J.; Pabst, M.; Dekker, C.
10.1101/2024.10.17.618837 — biophysics — Posted on 2024-10-18
2322 Clonal-aggregative multicellularity entrained by salinity in one of the closest relative of animals
Ros-Rocher, N.; Reyes-Rivera, J.; Horo, U.; Foroughijabbari, Y.; Combredet, C.; Larson, B. T.; Coyle, M. C.; Houtepen, E. A. T.; Vermeij, M. J. A.; Steenwyk, J. L.; Brunet, T.
10.1101/2024.03.25.586565 — evolutionary biology — Posted on 2024-10-18
2324 Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution
Uveira, J.; Donati, A.; Leria, M.; Lechable, M.; Lahaye, F.; Vesque, C.; Houliston, E.; Momose, T.
10.1101/2024.09.05.609312 — developmental biology — Posted on 2024-10-18
2325 Exploring the Antifibrotic Potential of the heparan sulfate mimetic OTR4120: Insights from Preclinical Models
Marega, M.; Mejdoubi-Charef, N.; Wiegard, D.; Khan, M. M.; Bartkuhn, M.; Gambs, L.; Procida-Kowalski, T.; Wilhelm, J.; Vasquez-Pacheco, E.; Noori, A.; Zheng, Y.; Xuran, C.; Lingampally, A.; Zukowska, J.; Charef, S.; Chiappini, F.; Choppin, A.; PAPY-GARCIA, D.; Pepperkok, R.; Muley, T.; Winter, H.; Ruppert, C.; Seeger, W.; Gunther, A.; Barritault, D.; Chen, C.; Chao, C.; Rivetti, S.; Bellusci, S.
10.1101/2024.10.17.618798 — cell biology — Posted on 2024-10-18
2328 A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathies
An, S.; McInnis, J. J.; Kim, D.; Li, Y.; Yilmaz, O.; Ahn, J.; Mackness, B. C.; Park, J.; Bonner, J. M.; Yun, H.; Dujardin, S.; Kim, D.; Kwon, S.-H.; Tang, Y.; Pradier, L.; Hyeon, S.; Song, D.; Sung, B.; Krishnan, R.; Spencer, B.; Rissman, R.; Sandhu, J.; Haqqani, A.; Lee, H.; Jung, J.; You, W.-K.; Star, A. T.; Delaney, C.; Stanimirovic, D.; Sardi, S. P.; Lee, S. H.; Kayatekin, C.
10.1101/2024.10.16.618734 — neuroscience — Posted on 2024-10-18
2329 Art's Hidden Topology: A window into human perception
Dmitriuk, E.; Bajno, B.; Dreszer, J.; Bałaj, B.; Ratajczak, E.; Hajnowski, M.; Janik, R.; Kus, M.; Kadir, S. N.; Rogala, J.
10.1101/2024.10.16.618741 — neuroscience — Posted on 2024-10-18
2331 A galanin-positive population of lumbar spinal cord neurons modulates sexual arousal and copulatory behavior
Lenschow, C.; Mendes, A. P.; Ferreira, L.; Lacoste, B.; Marques, H.; Gutierrez-Castellanos, N.; Quilgars, C.; Bertrand, S. S.; Lima, S. Q.
10.1101/2022.10.04.510783 — neuroscience — Posted on 2024-10-18
2335 Thermal Proteome Profiling reveals rapid proteomic responses to redox changes in specific cellular compartments
Revazian, A.; Nesterenko, A. M.; Ezerina, D.; Luo, T.; Vertommen, D. M.; Gibhardt, C. S.; Bogeski, I.; Messens, J.; Belousov, V. V.
10.1101/2024.10.17.618419 — systems biology — Posted on 2024-10-18
2336 A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus
Shahreen, N.; Ahm, J.; Alsiyabi, A.; Chowdhury, N. B.; Shinde, D.; Chaudhari, S. S.; Bayles, K.; Thomas, V. C.; Saha, R.
10.1101/2024.10.16.618751 — systems biology — Posted on 2024-10-18
2339 Federated deep learning enables cancer subtyping by proteomics
Cai, Z.; Boys, E. L.; Noor, Z.; Aref, A.; Xavier, D.; Lucas, N.; Williams, S. G.; Koh, J. M. S.; Poulos, R. C.; Wu, Y.; Dausmann, M.; MacKenzie, K. L.; Aguilar-Mahecha, A.; Armengol, C.; Barranco, M. M.; Basik, M.; Bowman, E. D.; Clifton-Bligh, R. J.; Connolly, E. A.; Cooper, W. A.; Dalal, B.; DeFazio, A.; Filipits, M.; Flynn, P. J.; Graham, J. D.; George, J.; Gill, A. J.; Gnant, M.; Habib, R.; Harris, C. C.; Harvey, K.; Horvath, L. G.; Jackson, C.; Kohonen-Corish, M. R. J.; Lim, E.; Liu, J.; Long, G.; Lord, R. V.; Mann, G. J.; McCaughan, G. W.; Morgan, L.; Murphy, L. C.; Nagabushan, S.; Nagri
10.1101/2024.10.16.618763 — cancer biology — Posted on 2024-10-18
2341 Human TRPV4 engineering yields an ultrasound-sensitive actuator for sonogenetics
Zhao, L.; Xu, K.; Talyzina, I.; Shi, J.; Li, S.; Yang, Y.; Zhang, S.; Zheng, j.; Sobolevsky, A.; Chen, H.; Cui, J.
10.1101/2024.10.16.618766 — biophysics — Posted on 2024-10-18
2344 Critical-Size Defect Tibialis Anterior (TA) Muscle Regeneration using Ex-Vivo Mice Hindlimbs Culturing under Dynamic Mechanical Loading
Jacho, D.; Huynh, J.; Crowe, E.; Rabino, A.; Yildirim, M.; Czernik, P. J.; Lecka-Czernik, B.; Garcia-Mata, R.; Yildirim-Ayan, E.
10.1101/2024.10.16.618565 — bioengineering — Posted on 2024-10-18
2346 Facial Coloration as a Social Signal in a Neotropical Cichlid: Testing the Facial Expression Hypothesis
Satoh, S.; Fukuda, K.; Matsuo, S.; Banda, T.; Banda, T.; Kanbe, K.; Konno, A.; Takei, S.; Kohda, M.; Kutsukake, N.
10.1101/2024.10.17.618800 — animal behavior and cognition — Posted on 2024-10-18
2347 Evolution of Key Factors Influencing Performance Across Phases in Junior Short Sprints
Oku, K.; Kai, Y.; Koda, H.; Gonno, M.; Tanaka, M.; Matsui, T.; Watanabe, Y.; Morihara, T.; Kida, N.
10.1101/2024.10.16.618610 — animal behavior and cognition — Posted on 2024-10-18
2350 The Circadian Isoform Landscape of Mouse Livers
Zee, A.; Deng, D. Z. Q.; DiTacchio, L.; Vollmers, C.
10.1101/2024.10.16.618716 — genomics — Posted on 2024-10-18
2351 Methylation Clocks Do Not Predict Age or Alzheimer's Disease Risk Across Genetically Admixed Individuals
Cruz-Gonzalez, S.; Gu, E.; Gomez, L.; Mews, M.; Vance, J. M.; Cuccaro, M. L.; Cornejo-Olivas, M. R.; Feliciano-Astacio, B. E.; Byrd, G. S.; Haines, J. L.; Pericak-Vance, M. A.; Griswold, A. J.; Bush, W. S.; Capra, J. A.
10.1101/2024.10.16.618588 — genomics — Posted on 2024-10-18
2352 Simple models of non-random mating and environmental transmission bias standard human genetics statistical methods
Border, R.; Wang, J.; Caggiano, C.; Sankararaman, S.; Schork, A. J.; Turley, P.; Young, A. S.; Benjamin, D. J.; Dahl, A. W.; Zaitlen, N.
10.1101/2024.10.16.618755 — genetics — Posted on 2024-10-18
2353 Predicting the natural yeast phenotypic landscape with machine learning
Khaiwal, S.; De Chiara, M.; Barre, B. P.; Barrio-Hernandez, I.; Stenberg, S.; Beltrao, P.; Warringer, J.; Liti, G.
10.1101/2024.10.17.618784 — genetics — Posted on 2024-10-18
2355 The biogeography of evolutionary radiations on oceanic archipelagos
Bree, B.; Matthews, T. J.; Fernandez-Palacios, J. M.; Paroissin, C.; Triantis, K. A.; Whittaker, R. J.; Rigal, F.
10.1101/2024.10.07.616413 — evolutionary biology — Posted on 2024-10-18
2356 Molecular properties of RmlT, a wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes.
Monteiro, R.; Cereija, T. B.; Pombinho, R.; Voskuilen, T.; Codee, J.; Sousa, S.; Morais Cabral, J.; Cabanes, D.
10.1101/2024.01.23.574818 — microbiology — Posted on 2024-10-18
2358 Partial Correlation as a Tool for Mapping Functional-Structural Correspondence in Human Brain Connectivity
Santucci, F.; Jimenez-Marin, A.; Gabrielli, A.; Bonifazi, P.; Ibanez-Berganza, M.; Gili, T.; Cortes, J. M.
10.1101/2024.10.16.618230 — neuroscience — Posted on 2024-10-18
2360 An AI-Driven Model of Consciousness, Its Disorders, and Their Treatment
Toker, D.; Thum, J.; Guang, J.; Miyamoto, H.; Yamakawa, K.; Vespa, P. M.; Schnakers, C.; Bari, A.; Hudson, A.; Pouratian, N.; Monti, M. M.
10.1101/2024.10.16.618720 — neuroscience — Posted on 2024-10-18
2361 Divergent and Convergent TMEM106B Pathology in Murine Models of Neurodegeneration and Human Disease
Du, M.; Akerman, S. C.; Fare, C.; Ruan, L.; Vidensky, S.; Mamedova, L.; Lee, J.; Rothstein, J. D. D.
10.1101/2024.10.16.618765 — neuroscience — Posted on 2024-10-18
2363 Benchmarking Stroke Outcome Prediction through Comprehensive Data Analysis - NeuralCup 2023
Matsulevits, A.; Alvez, P.; Atzori, M.; Beyh, A.; Corbetta, M.; Del Pup, F.; Dulyan, L.; Foulon, C.; Hope, T.; Ioannucci, S.; Jobard, G.; Lemaitre, H.; Neville, D.; Nozais, V.; Rorden, C.; Saprikis, O.-V.; Sibon, I.; Sperber, C.; Teghipco, A.; Thirion, B.; Tshimanga, L. F.; Umarova, R.; Vaidelyte, E. B.; van den Hoven, E.; Villar Rodriguez, E.; Zanola, A.; Tourdias, T.; Thiebaut de Schotten, M.
10.1101/2024.10.17.618691 — neuroscience — Posted on 2024-10-18
2366 Sleep-Induced Vasomotor Pulsation is a Driver of Cerebrospinal Fluid and Blood-Brain Barrier Dynamics in the Human Brain
Väyrynen, T.; Tuunanen, J.; Helakari, H.; Korhonen, V.; Huotari, N.; Piispala, J.; Kallio, M.; Kiviniemi, V.
10.1101/2024.10.16.618430 — neuroscience — Posted on 2024-10-18
2370 Rigor and Reproducibility of Digital Spatial Profiling on Clinically Sourced Human Tissues
Smith, K. D.; MacDonald, J. W.; Li, X.; Beirne, E.; Stewart, G.; Bammler, T. K.; Akilesh, S.
10.1101/2024.10.16.618750 — pathology — Posted on 2024-10-18
2379 Spatial and seasonal biodiversity variation in a large Mediterranean lagoon using environmental DNA metabarcoding through sponge tissue collection
Corral-Lou, A.; Ramon-Laca, A.; Alcaraz, L.; Cassidy, R. D.; Taboada, S.; Mariani, S.; Mercado, B.; Vicente, M.; Perez-Ruzafa, A.; Gallego, R.; Riesgo, A.
10.1101/2024.10.17.618912 — ecology — Posted on 2024-10-18
2381 Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis
Parker, M. E.; Mehta, N. U.; Liao, T.-C.; Tomaszewski, W. H.; Snyder, S. A.; Busch, J.; Ciofani, M.
10.1101/2024.10.15.618522 — immunology — Posted on 2024-10-18
2383 Astrocytic Ryk signaling coordinates scarring and wound healing after spinal cord injury
Shen, Z.; Feng, B.; Lim, W.; Woo, T.; Liu, Y.; Vicenzi, S.; Wang, J.; Kwon, B. K.; Zou, Y.
10.1101/2024.10.16.618727 — neuroscience — Posted on 2024-10-18
2385 Macrophage crosstalk with neural progenitors and fibroblasts controls regenerative neurogenesis via Sema4ab after spinal cord injury in zebrafish
Docampo Seara, A.; Cosacak, M. I.; Heilemann, K.; Kessel, F.; Oprisoreanu, A. M.; Cark, O.; Zoeller, D.; Arnold, J.; Bretschneider, A.; Hnatiuk, A.; Ninov, N.; Becker, C. G.; Becker, T.
10.1101/2024.10.16.618445 — neuroscience — Posted on 2024-10-18
2388 A deep learning approach to detect and visualise sexual dimorphism in monomorphic species
Silva, N. J.; Ferreira, A. C.; Silva, L. R.; Perret, S.; Tieo, S.; Renoult, J. P.; Covas, R.; Doutrelant, C.
10.1101/2024.10.16.618646 — zoology — Posted on 2024-10-18
2389 Genetic diversity and fine-scale structure of two populations of a subterranean rodent, Ellobius talpinus
Rudyk, A. I.; Kuprina, K.; Bergaliev, A. M.; Galkina, S. A.; Romanovich, A. E.; Novikov, E. A.; Volodina, E. V.; Smorkatcheva, A. V.
10.1101/2024.10.16.618669 — zoology — Posted on 2024-10-18
2393 Plant phenotypic differentiation outweighs genetic variation in shaping the lettuce leaf microbiota
Capparotto, A.; Chesneau, G.; Tondello, A.; Stevanato, P.; Bonato, T.; Squartini, A.; Hacquard, S.; Giovannetti, M.
10.1101/2024.10.16.618533 — plant biology — Posted on 2024-10-18
2396 Role of CCK1 receptor in metabolic benefits of intestinal enteropeptidase inhibition in mice
Hinke, S. A.; Albarazanji, K.; Cavanaugh, C.; Liu, J.; Beck, S.; Shukla, N.; Meng, R.; Ho, G.; Camacho, R. C.; Leonard, J.; Nawrocki, A. R.
10.1101/2024.10.17.618852 — pharmacology and toxicology — Posted on 2024-10-18
2397 Pharmacoproteomic profiling identifies secreted markers for aberrant drug action
Knecht, S.; Kalxdorf, M.; Korben, J.; Mathieson, T.; Sevin, D. C.; Kuster, B.; Kasprowicz, R.; Sakatis, M. Z.; Eberl, H. C.; Bantscheff, M.
10.1101/2024.10.16.618637 — pharmacology and toxicology — Posted on 2024-10-18
2398 Deciphering stiffness-driven changes in colorectal cancer by proteomics
Cresens, C.; Montero-Calle, A.; Solis-Fernandez, G.; Shaghaghi, B.; Gerrits, L.; Aytekin, S.; Kouwer, P. H. J.; Barderas, R.; Rocha, S.
10.1101/2024.10.16.618701 — cancer biology — Posted on 2024-10-18
2399 Path2Space: An AI Approach for Cancer Biomarker Discovery Via Histopathology Inferred Spatial Transcriptomics
Shulman, E. D.; Campagnolo, E. M.; Lodha, R.; Cantore, T.; Hu, T.; Nasrallah, M.; Hoang, D.-T.; Aldape, K.; Ruppin, E.
10.1101/2024.10.16.618609 — cancer biology — Posted on 2024-10-18
2400 PRMT5-mediated histone methylation regulates alternative splicing via MECP2-PTBP1 to promote EMT in breast cancer hypoxia
Mutnuru, S. A.; Yadav, P.; Kakani, P.; Dhamdhere, S. G.; Kumari, P.; Agarwal, S.; Samaiya, A.; Shukla, S.
10.1101/2024.10.16.618678 — cancer biology — Posted on 2024-10-18
2401 Ductal pancreatic cancer interception by FGFR2 abrogation
Tonelli, C.; Deschenes, A.; Gaeth, V.; Jensen, A.; Vithlani, N.; Yao, M. A.; Zhao, Z.; Park, Y.; Tuveson, D.
10.1101/2024.10.16.618726 — cancer biology — Posted on 2024-10-18
2402 Voluntary Exercise Attenuates Tumor Growth in a Preclinical Model of Castration-Resistant Prostate Cancer
Berger, N.; Kugler, B.; Han, D.; Li, M.; Nguyen, P.; Anderson, M.; Zhang, S.; Cai, C.; Zou, K.
10.1101/2024.10.16.617081 — cancer biology — Posted on 2024-10-18
2406 An integrative spatial multi-omic workflow for unified analysis of tumor tissue
Kriel, J.; Moffet, J. J.; Lu, T.; Fatunla, O. E.; Narayana, V. K.; Valkovic, A.; Maluenda, A.; McConville, M. J.; Tsui, E.; Whittle, J. R.; Best, S. A.; Freytag, S.
10.1101/2024.10.15.618574 — bioinformatics — Posted on 2024-10-18
2409 Du-IN-v2: Unleashing the Power of Vector Quantization for Decoding Cognitive States from Intracranial Neural Signals
Zheng, H.; Wang, H.-T.; Jiang, W.-B.; Chen, Z.-T.; He, L.; Lin, P.-Y.; Wei, P.-H.; Zhao, G.-G.; Liu, Y.-Z.
10.1101/2024.10.16.618686 — bioengineering — Posted on 2024-10-18
2410 Discovery and Biosynthesis of Sulfenicin and Its New-to-Nature Acylsulfenic Acid Functional Group
Xue, D.; Zou, H.; Lv, W.; Madden, M. D.; Lian, X.; Xu, M.; Pulliam, C.; Older, E. A.; Hou, L.; Campbell, A.; de Rond, T.; Awakawa, T.; Yuan, C.; Moore, B. S.; Li, J.
10.1101/2024.10.16.618611 — biochemistry — Posted on 2024-10-18
2413 The cGAS-STING pathway is an in vivo modifier of genomic instability syndromes
Bergman, M.; Goshtchevsky, U.; Atlan, T.; Astre, G.; Halabi, R.; El, H.; Moses, E.; Lemus, A. J. J.; Benayoun, B. A.; Tzfati, Y.; Ben-Ami, I.; Harel, I.
10.1101/2024.10.16.618655 — genetics — Posted on 2024-10-18
2419 Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control
Koksal, H.; Herbst, M.; Pereira, P.; Nater, M.; Regli, N.; Boudjeniba, C.; Erdem Borgoni, N.; Cecconi, V.; van den Broek, M.
10.1101/2024.10.16.618635 — immunology — Posted on 2024-10-18
2421 Genetic and functional diversity of allorecognition receptors in the urochordate, Botryllus schlosseri
Rodriguez-Valbuena, H.; Salcedo, J.; De Their, O.; Flot, J.-F.; Tiozzo, S.; De Tomaso, A. W.
10.1101/2024.10.16.618699 — immunology — Posted on 2024-10-18
2423 Corticostriatal Maldevelopment in the R6/2 Mouse Model of Juvenile Huntington Disease
Cepeda, C.; Holley, S. M.; Barry, J.; Oikonomou, K. D.; Yazon, V.-W.; Peng, A.; Argueta, D.; Levine, M. S.
10.1101/2024.10.15.618500 — neuroscience — Posted on 2024-10-18
2425 Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2
Vecchiarelli, H. A.; Bisht, K.; Sharma, K. P.; Weiser Novak, S.; Traetta, M. E.; Garcia-Segura, M. E.; St-Pierre, M.-K.; Savage, J. C.; Willis, C.; Picard, K.; Bordeleau, M.; Vernoux, N.; Khakpour, M.; Garg, R.; Loewen, S. M.; Murray, C. J.; Grinberg, Y. Y.; Faustino, J.; Halvorson, T.; Lau, V.; Pluchino, S.; Vexler, Z. S.; Carson, M. J.; Manor, U.; Peruzzotti-Jametti, L.; Tremblay, M.-E.
10.1101/2024.10.15.618087 — neuroscience — Posted on 2024-10-18
2427 Chronic recording of brain activity in awake toads
Shaykevich, D. A.; Woods, G. A.; O'Connell, L. A.; Hong, G.
10.1101/2024.10.16.618567 — neuroscience — Posted on 2024-10-18
2428 Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression
Tuechler, N.; Burtscher, M. L.; Garrido-Rodriguez, M.; Khan, M. M.; Turei, D.; Tischer, C.; Kaspar, S.; Schwarz, J. J.; Stein, F.; Rettel, M.; Kramann, R.; Savitski, M. M.; Saez-Rodriguez, J.; Pepperkok, R.
10.1101/2024.10.15.618507 — systems biology — Posted on 2024-10-18
2430 Revisiting the evolution and function of NIP2 parologs in the Rhynchosporium spp. complex
Darma, R.; Yu, D. S.; Outram, M. A.; Sung, Y.-C.; Hill, E. H.; Croll, D.; Williams, S. J.; Ovenden, B.; Milgate, A.; Solomon, P. S.; McDonald, M. C.
10.1101/2024.10.15.618441 — plant biology — Posted on 2024-10-18
2431 Defense mechanisms in Lupinus luteus against Colletotrichum lupini, involving TIR-NBS-LRR protein, hypersensitive response and phenylpropanoid pathways
Godoy, G. A.; Levicoy, D.; Martinez-Hernandez, J. E.; Rupayan, A.; Hernandez, S.; Carrasco, M.; Caligari, P. D.; Baroncelli, R.; Garrido, H. S.
10.1101/2024.10.15.618496 — plant biology — Posted on 2024-10-18
2432 The role of IAA and its transport in the complex streptophyte algae Chara braunii
Kurtovic, K.; Vosolsobe, S.; Nedved, D.; Müller, K.; Dobrev, P.; Schmidt, V.; Piszczek, P.; Kuhn, A.; Smoljan, A.; Fisher, T. J.; Weijers, D.; Friml, J.; Bowman, J. L.; Petrasek, J.
10.1101/2024.10.16.618682 — plant biology — Posted on 2024-10-18
2435 Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells
Dong, F.; Zhang, S.; Song, K.; Jiang, L.; Hu, L.-P.; Li, Q.; Zhang, X.-L.; li, j.; Feng, M.; Cai, Z.-W.; Yao, H.-F.; Li, R.-k.; Li, H.; Chen, J.; Hu, X.; Wang, J.; Jiang, C.; Zhu, H. H.; Wang, C.; Da, L.; Zhang, Z.; Bao, Z.; Wang, X.; Jiang, S.
10.1101/2024.10.15.618536 — cancer biology — Posted on 2024-10-18
2437 Co-delivery of Paclitaxel and Cannabidiol in Lipid Nanoparticles Enhances Cytotoxicity Against Melanoma Cells
de Carvalho, F. V.; Geronimo, G.; de Moura, L. D.; Mendonca, T. C.; Breitkreitz, M. C.; de Paula, E.; da Silva, G. H. R.
10.1101/2024.10.15.618512 — cancer biology — Posted on 2024-10-18
2438 Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer
Anastasiadou, D. P.; Couturier, N.; Goel, S.; Argyris, D. G.; Vodopyanov, S.; Rivera-Sanchez, L.; Gonzalez, E.; Kreger, J.; Griffen, A.; Kazakov, A.; Burt, J.; Recoder, N.; Duran, C. L.; Harney, A. S.; Quesnel, A.; Filippou, P. S.; Lenis, V. P.; Shukla, S.; Entenberg, D.; Zintiridou, A.; Chen, X.; Eddy, R. J.; Oktay, M. H.; Condeelis, J. S.; Karagiannis, N. S.; Briceno, A.; Guzik, H.; Alon, R.; DesMarais, V.; Ioannou, G.; Gnjatic, S.; Raynolds, D. M.; Macedo, R.; Reshef, R.; Gil-Henn, H.; MacLean, A. L.; Roussos Torres, E.; LaFave, L. M.; Lauvau, G.; Karagiannis, G. S.
10.1101/2024.10.15.618571 — cancer biology — Posted on 2024-10-18
2444 Load-based divergence in the dynamic allostery of two TCRs recognizing the same pMHC
Chang-Gonzalez, A. C.; Akitsu, A.; Mallis, R. J.; Lang, M. J.; Reinherz, E. L.; Hwang, W.
10.1101/2024.10.16.618634 — biophysics — Posted on 2024-10-18
2445 Chromatin Buffers Torsional Stress During Transcription
Qian, J.; Lubkowska, L.; Zhang, S.; Tan, C.; Hong, Y.; Fulbright, R. M.; Inman, J. T.; Kay, T. M.; Jeong, J.; Gotte, D.; Berger, J. M.; Kashlev, M.; Wang, M. D.
10.1101/2024.10.15.618270 — biophysics — Posted on 2024-10-18
2446 A percolation-type criticality threshold controls immune protein coating of surfaces
Wang, Z.; Kulkarni, S.; Nong, J.; Zamora, M. E.; Ebrahimimojarad, A.; Hood, E.; Shuvaeva, T.; Zaleski, M.; Gullipalli, D.; Wolfe, E.; Espy, C.; Arguiri, E.; Wang, Y.; Marcos-Contreras, O. A.; Song, W.; Muzykantov, V. R.; Fu, J.; Radhakrishnan, R.; Myerson, J. W.; Brenner, J. S.
10.1101/2024.10.15.618530 — biophysics — Posted on 2024-10-18
2447 HP1a promotes chromatin liquidity and drives spontaneous heterochromatin compartmentalization
Brennan, L. D.; Kim, H.-K.; Colmenares, S.; Ego, T.; Kumar, A.; Safran, S.; Ryu, J.-K.; Karpen, G.
10.1101/2024.10.18.618981 — biophysics — Posted on 2024-10-18
2448 Carafe enables high quality in silico spectral library generation for data-independent acquisition proteomics
Wen, B.; Hsu, C.; Zeng, W.-F.; Riffle, M.; Chang, A.; Mudge, M.; Nunn, B. L.; Berg, M. D.; Villen, J.; MacCoss, M. J.; Noble, W. S.
10.1101/2024.10.15.618504 — bioinformatics — Posted on 2024-10-18
2450 Interactive design and validation of antibody panels using single-cell RNA-seq atlases
Watson, M.; Latour, S.; Abazari, G.; Geuenich, M. J.; Poon, E.; Cao, R.; Mrkonjic, M.; McGuigan, A. P.; Jackson, H. W.; Campbell, K. R.
10.1101/2024.10.15.618479 — bioinformatics — Posted on 2024-10-18
2452 Fast Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers
Cairns, J. L.; Huber, J.; Lewen, A.; Jung, J.; Maurer, S. J.; Bausbacher, T.; Schmidt, S.; Levkin, P. A.; Sevin, D.; Goepfrich, K.; Koch, P.; Kann, O.; Hopf, C.
10.1101/2024.10.15.618420 — bioinformatics — Posted on 2024-10-18
2453 Generation of cultured beef from bovine embryonic stem cells
Rui, X.; Li, Z.; Xu, J.; Dai, J.; Zhang, X.; Jin, X.; Liu, Y.
10.1101/2024.10.15.618593 — bioengineering — Posted on 2024-10-18
2457 Reconstructing the sequence specificities of RNA-binding proteins across eukaryotes
Sasse, A.; Ray, D.; Laverty, K. U.; Tam, C. L.; Albu, M.; Zheng, H.; Lyudovyk, O.; Dalal, T.; Nie, K.; Magis, C.; Notredame, C.; Weirauch, M. T.; Hughes, T. R.; Morris, Q.
10.1101/2024.10.15.618476 — genomics — Posted on 2024-10-18
2460 Convergent evolution of epigenome recruited DNA repair across the Tree of Life
Monroe, G.; Lee, C.; Quiroz, D. P.; Lensink, M.; Oya, S.; Davis, M. T.; Long, E.; Bird, K. A.; Pierce, A. V.; Zhao, K.; Runcie, D. E.
10.1101/2024.10.15.618488 — evolutionary biology — Posted on 2024-10-18
2466 Suppressing PDGFRβ Signaling Enhances Myocyte Fusion to Promote Skeletal Muscle Regeneration
Xue, S.; Benvie, A. M.; Blum, J. E.; Kolba, N. J.; Cosgrove, B. D.; Thalacker-Mercer, A.; Berry, D. C.
10.1101/2024.10.15.618247 — developmental biology — Posted on 2024-10-18
2467 Regulator of G-Protein Signaling 2 Knockout in CD4+ T Cells Promotes Anti-Inflammatory T Cells, Enhancing Ovulation, and Oocyte Yield
Raff, M.; Benton, T.; Brummons, D.; Kovach, D.; Bunton, O.; Janky, E.; Scroggins, D. G.; Duran, E. H.; Gray, G.; Scroggins, S. M.
10.1101/2024.10.15.618561 — immunology — Posted on 2024-10-18
2468 A resource for extracellular vesicles from activated CD4 T cells that relay pro-inflammatory signals
Jainarayanan, A. K.; Mahla, R. S.; Capera, J.; ELANCHEZHIAN, M.; Gupta, D.; Anand, N. M.; Thomas, T.; Beckers, D.; Leithner, A.; Achar, S. R.; Valvo, S.; Conceicao, M.; Kurz, E.; Devaprasad, A.; Amin, S.; Berridge, G.; Hester, S.; Fischer, R.; Cespedes, P. F.; Dustin, L. B.; Wood, M. J. A.; Dustin, M. L.
10.1101/2024.10.15.618584 — immunology — Posted on 2024-10-18
2469 Human Anti-Glycan Reactivity is Driven by the Selection of B cells Utilizing Private Antibody Gene Rearrangements that are Affinity Maturated in Germinal Centers
New, J. S.; Fucile, C. F.; Callahan, A. R.; Burke, J. N.; Davis, R. S.; Duck, W. L.; Rosenberg, A. F.; Kearney, J. F.; King, R. G.
10.1101/2024.10.15.618486 — immunology — Posted on 2024-10-18
2470 Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus
Elshikha, A.; Ge, Y.; Choi, S. C.; Park, Y. P.; Padilla, L.; Zhu, Y.; Clapp, W. L.; Sobel, E. S.; Mohamadzadeh, M.; Morel, L.
10.1101/2024.10.15.618563 — immunology — Posted on 2024-10-18
2473 FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult CNS
Collins, H. Y.; Doan, R. A.; Li, J.; Early, J. E.; Madden, M. E.; Simkins, T.; Lyons, D. A.; Monk, K. R.; Emery, B.
10.1101/2024.10.15.618515 — neuroscience — Posted on 2024-10-18
2474 Human Astrocytes Synchronize Neural Organoid Networks
Patel, M. D.; Lavekar, S. S.; Jaisalmeria, R.; Oji, S.; Jayasi, J.; Cvetkovic, C.; Krencik, R.
10.1101/2024.10.17.618921 — neuroscience — Posted on 2024-10-18
2476 Sensorimotor integration enhances temperature stimulus processing
Anderson, L. S.; Costabile, J. D.; Schwinn, S.; Calderon, D.; Haesemeyer, M.
10.1101/2024.10.15.618474 — neuroscience — Posted on 2024-10-18
2479 IOP-induced blood-retinal barrier compromise contributes to RGC death in glaucoma
Zhang, C.; Simon, M.; Lim, H.; Tolman, N. G.; Horbal, L.; Juarez, F. A.; Bhandari, A.; Montgomery, C.; John, S. W. M.
10.1101/2024.10.15.618539 — neuroscience — Posted on 2024-10-18
2480 Epigenetic derepression of H3K9me3 mitigates Alzheimer-related pathology and improves cognition via immunomodulation and Vgf induction
Fuchs, D.-T.; Vit, J.-P.; Rentsendorj, A.; Sheyn, J.; Shi, H.; Koronyo, Y.; Chepurna, O.; Davis, M. R.; Wilson, J. W.; Schneider, L. S.; Graham, S. L.; Gupta, V. K.; Fahnestock, M.; Sun, T.; Kleinman, M. T.; Horne, D.; Mirzaei, M.; Black, K. L.; Koronyo-Hamaoui, M.
10.1101/2024.10.15.618518 — neuroscience — Posted on 2024-10-18
2481 Integrated temporal profiling of iPSCs-derived motor neurons from ALS patients carrying C9orf72, FUS, TARDBP, and SOD1 mutations
Ma, G.; Xia, C.; Lyu, B.; Liu, J.; Luo, F.; Guan, M.; Wang, J.; Sun, L.; Zhang, L.; Chen, Y.; Mao, Y.; Yu, G.; Wang, W.
10.1101/2024.10.15.618602 — neuroscience — Posted on 2024-10-18
2484 Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease
Zhu, B.; Wangzhou, A.; Yu, D.; Li, T.; Schmidt, R.; De Florencio, S. L.; Chao, L.; Perez, Y.; Grinberg, L. T.; Spina, S.; Ransohoff, R. M.; Kriegstein, A.; Seeley, W. W.; Nowakowski, T. J.; Piao, X.
10.1101/2024.10.15.618329 — neuroscience — Posted on 2024-10-18
2485 Gut bacteria-derived succinate induces enteric nervous system regeneration
Aydin, B.; Mamede, I.; Cardoso, J.; Deere, J.; Alvarez, Y.; Qiao, S.; Sharma, V. P.; Scavuzzo, M. A.; Donaldson, G. P.; Guo, C.-J.; Mucida, D.
10.1101/2024.10.15.618589 — neuroscience — Posted on 2024-10-18
2488 Lifespan of male and female APP/PS1 and APPNL-F/NL-F mouse models of Alzheimer's disease
Roberts, H.; Fang, Y.; Quinn, K.; Hill, T.; Peck, M. R.; Bartke, A.; Hascup, K. N.; Hascup, E. R.
10.1101/2024.10.15.618508 — physiology — Posted on 2024-10-18
2489 RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination
Gruet, M.; Xu, Y.; An, L.; Ma, Y.; Balcells, C.; Tyson, K.; Spear, S.; Xu, Y.; McKinney, F.; Babuta, J.; Bray, C.; Wickremesinghe, C.; Siskos, A. P.; Nijhuis, A. M.; Tate, E. W.; McNeish, I. A.; Benito, A.; Keun, H. C.
10.1101/2024.10.15.618473 — cancer biology — Posted on 2024-10-18
2490 ECM-free patient-derived organoids preserve diverse prostate cancer lineages and uncover in vitro-enriched cell types
Dolgos, R.; Parmentier, R.; Wang, J.; Servant, R.; Templeton, A. J.; Zellweger, T.; Lamb, A. D.; Mertz, K. D.; Subotic, S.; Vlajnic, T.; Seifert, H.; Mortezavi, A.; Rentsch, C. A.; Bubendorf, L.; Le Magnen, C.
10.1101/2024.10.16.618617 — cancer biology — Posted on 2024-10-18
2492 Human Topoisomerase IIα Promotes Chromatin Condensation Via a Phase Transition
Wu, M.; Beck, C.; Lee, J. H.; Fulbright, R. M.; Jeong, J.; Inman, J. T.; Woodhouse, M. V.; Berger, J. M.; Wang, M. D.
10.1101/2024.10.15.618281 — biophysics — Posted on 2024-10-18
2495 Multimodal learning of transcriptomes and text enables interactive single-cell RNA-seq data exploration with natural-language chats
Schaefer, M.; Peneder, P.; Malzl, D.; Peycheva, M.; Burton, J.; Hakobyan, A.; Sharma, V.; Krausgruber, T.; Menche, J.; Tomazou, E. M.; Bock, C.
10.1101/2024.10.15.618501 — bioinformatics — Posted on 2024-10-18
2496 The First Comprehensive Description of the Platelet Single Cell Transcriptome
Wolfsberger, W.; Dietz, C.; Foster, C.; Oleksyk, T. K.; Washington, V.; Lynch, D.
10.1101/2024.10.15.618506 — bioinformatics — Posted on 2024-10-18
2497 A lineage-specific nascent RNA assay unveils principles of gene regulation in tissue biology
Chovatiya, G.; Wang, A. B.; Versluis, P.; Bai, C. K.; Huang, S. Y.; DeBerardine, M.; Ray, J.; Ozer, A.; Lis, J.; Tumbar, T.
10.1101/2024.10.15.618417 — genomics — Posted on 2024-10-18
2499 Estimating the rate of sexual reproduction and the inbreeding rate in Leishmania
Nicoll, A. G.; Kilford, H.; Grace, C. A.; Reis-Cunha, J. L.; Jeffares, D. C.; Constable, G. W. A.
10.1101/2024.10.15.618469 — genetics — Posted on 2024-10-18
2500 Genes Underlying Adaptive Physiological Shifts Among Hibernating Mammals
Drabeck, D. H.; Anderson, M.; Roback, E.; Lusczek, E. R.; Tri, A. N.; Kowalczyk, A.; Lassen, J. F.; McGaugh, S. E.; Iles, T.
10.1101/2024.10.15.618548 — evolutionary biology — Posted on 2024-10-17
2504 Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling
Dreyer, H. H. M.; Ithakisiou, G.-N.; Spelier, S.; Iwanski, M. K.; Katrukha, E.; Terstappen, J.; Rodenburg, L. W.; den Hertog-Oosterhoff, L. A.; Smits, S. M. A.; van der Windt, I. S.; Azink, L. T.; Bijlard, L. H. M.; Passier, K.; van Beuningen, S. F. B.; Lebbink, R. J.; Haarman, E. G.; van der Ent, C. K.; Kapitein, L. C.; Bont, L. J.; Beekman, J. M.; Amatngalim, G. D.
10.1101/2024.10.17.618953 — cell biology — Posted on 2024-10-17
2510 Mammary Epithelial Migration is EMT-Independent
Chen, J.; Ma, R.; Deng, Z.; Lu, Y.; Zhou, J.; Xia, K.; Klein, O. D.; Lu, P.
10.1101/2024.10.17.618667 — cell biology — Posted on 2024-10-17
2511 A limbal stem cell deficiency murine model with residual limbal stem cells
Someya, H.; Shirahama, S.; Karg, M. M.; Gregory-Ksander, M. S.; Dana, R.; Ksander, B. R.
10.1101/2024.10.17.618942 — cell biology — Posted on 2024-10-17
2513 A ZO-2 scaffolding mechanism regulates the Hippo signalling pathway.
Liu, O.; Lin, L.; Bunk, S.; Chew, T.; Wu, S.; Motegi, F.; Low, B. C.
10.1101/2024.10.17.618965 — cell biology — Posted on 2024-10-17
2517 Hydroxyurea induces ER stress and cytoplasmic protein aggregation
Sanchez-Molina, A.; Bernal, M.; Posligua Garcia, J. D.; Perez-Pulido, A. J.; de Cubas, L.; Hidalgo, E.; Salas-Pino, S.; Daga, R.
10.1101/2024.10.17.618805 — cell biology — Posted on 2024-10-17
2518 Locus-specific chromatin proteomics using dCas-guided proximity labelling in Aspergillus nidulans.
Svoboda, T.; Niederdockl-Loibl, D.; Schueller, A.; Hummel, K.; Schlosser, S.; Razzazi-Fazeli, E.; Strauss, J.
10.1101/2024.10.15.618449 — molecular biology — Posted on 2024-10-18
2519 PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
Wang, J.; Shi, Y.; Wang, Y.; Shen, Y.; Liu, H.; Sun, S.; Wang, Y.; Zhou, X.; Zhou, Y.; Zeng, X.; Li, J.; Chen, Q.
10.1101/2024.07.23.604769 — cancer biology — Posted on 2024-10-18
2520 Alternative splicing in mechanically stretched podocytes as a model of glomerular hypertension
Mattias, F.; Tsoy, O.; Hammer, E.; Gress, A.; Simm, S.; Lio, C. T.; Ameling, S.; Amann, K.; Dreher, L.; Wenzel, U.; Kacprowski, T.; List, M.; Kalinina, O.; Endlich, K.; Baumbach, J.; Voelker, U.; Endlich, N.; Kliewe, F.
10.1101/2024.07.17.603550 — cell biology — Posted on 2024-10-18
2526 Graphene-based micro-electrodes with reinforced interfaces and tunable porous structures for improved neural recordings
Dong, M.; Yang, J.; Zhen, F.; Du, Y.; Ding, S.; Yu, A.; Zou, R.; Qiu, L.; Guo, Z.; Coleman, H. A.; Parkington, H. C.; Fallon, J. B.; Forsythe, J. S.; Liu, M.
10.1101/2024.07.18.603459 — neuroscience — Posted on 2024-10-17
2527 Attentive graph neural network models for the prediction of blood-brain barrier permeability
Collins, J. W.; Ebrahimkhani, M.; Ramirez, D.; Abedi, M.; Philippe-Venec, L.; Cole, B. M.; Moore, B.; Nwankwo, J. O.
10.1101/2024.10.12.617907 — pharmacology and toxicology — Posted on 2024-10-17
2529 Replicating retroviral delivery of an IL-15 superagonist improves antitumor immunity and long-term survival in poorly immunogenic glioblastoma models
Haddad, A. F.; Saha, A.; Spatz, J.; Collins, S.; Lovalvo, I.; Gill, S.; Montoya, M. L.; Shukla, P.; Hong, J.; Wang, E.; Chuntova, P.; Lad, M.; Chalif, E.; Kasahara, N.; Aghi, M. K.
10.1101/2024.10.14.618095 — cancer biology — Posted on 2024-10-17
2530 Bacterial motility patterns adapt smoothly in response to spatial confinement and disorder
Zhang, H.; Wetherington, M. T.; Ko, H.; FitzGerald, C. E.; Munro, E. M.; Nirody, J. A.
10.1101/2024.09.29.615714 — biophysics — Posted on 2024-10-17
2534 Turnover of retroelements and satellite DNA drives centromere reorganizationover short evolutionary timescales in Drosophila
Courret, C.; Hemmer, L.; Wei, X.; Patel, P. D.; Chabot, B.; Fuda, N. J.; Geng, X.; Chang, C.-H.; Mellone, B.; Larracuente, A. M.
10.1101/2023.08.22.554357 — evolutionary biology — Posted on 2024-10-17
2535 Melanization interacts with soil mineral and microbial properties to determine fungal carbon and nitrogen persistence in soils
Beidler, K. V.; Huenupi, E.; DeLancey, L. C.; Maillard, F.; Zhang, B.; Persson, P.; Kennedy, P. G.; Phillips, R.
10.1101/2024.06.27.600831 — ecology — Posted on 2024-10-17
2537 An atypical E3 ligase safeguards the ribosome during nutrient stress
Douglas, T.; Zhang, J.; Wu, Z.; Abdallah, K.; McReynolds, M.; Gilbert, W. V.; Iwai, K.; Peng, J.; Young, L. H.; Crews, C. M.
10.1101/2024.10.10.617692 — cell biology — Posted on 2024-10-17
2539 TamL is a key player of the outer membrane homeostasis in Bacteroidetes.
Giovannercole, F.; De Smet, T.; Vences-Guzman, M. A.; Lauber, F.; Dugauquier, R.; Dieu, M.; Lizen, L.; Dehairs, J.; Lima-Mendez, G.; Guan, Z.; Sohlenkamp, C.; Renzi, F.
10.1101/2024.10.17.618404 — microbiology — Posted on 2024-10-17
2540 Impact of media brand on cefiderocol disk diffusion results
DeMarco, M. G.; Field, A. M.; Donohue, L. E.; Cox, H. L.; Kidd, T. S.; Barry, K. E.; Mathers, A. J.
10.1101/2024.10.17.618864 — microbiology — Posted on 2024-10-17
2541 A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation
Ge, A. Y.; Arab, A.; Dai, R.; Navickas, A.; Fish, L.; Garcia, K.; Asgharian, H.; Goudreau, J.; Lee, S.; Keenan, K.; Pappalardi, M. B.; McCabe, M. T.; Przybyla, L.; Goodarzi, H.; Gilbert, L.
10.1101/2022.12.14.518457 — cancer biology — Posted on 2024-10-17
2545 Ketogenesis protects against MASLD-MASH progression through fat oxidation-independent mechanisms
Queathem, E. D.; Stagg, D.; Nelson, A.; Chaves, A. B.; Crown, S. B.; Fulghum, K.; d`Avignon, D. A.; Ryder, J. R.; Bolan, P. J.; Hayir, A.; Gillingham, J. R.; Jannatpour, S.; Rome, F. I.; Williams, A. S.; Muoio, D. M.; Ikramuddin, S.; Hughey, C. C.; Puchalska, P.; Crawford, P. A.
10.1101/2024.10.17.618895 — biochemistry — Posted on 2024-10-17
2546 Fluorescent anionic cyanine plasma membrane probes for live cell and in vivo imaging
Danylchuk, D. I.; Khalin, I.; Suseela, Y. V.; Filser, S.; Plesnila, N.; Klymchenko, A. S.
10.1101/2024.10.17.618786 — biochemistry — Posted on 2024-10-17
2547 Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers
Dietmair, B.; Humphries, J.; Mercer, T. R.; Thurecht, K. J.; Howard, C. B.; Cheetham, S. W.
10.1101/2024.10.17.618962 — molecular biology — Posted on 2024-10-17
2548 Engineering mtDNA Deletions by Reconstituting End-Joining in Human Mitochondria
sfeir, a.; Fu, Y.; LAND, M.; Cui, R.; Kavlashvili, T.; Kim, M.; Lieber, T.; Ryu, K.; Debitetto, E.; Masilionis, I.; Saha, R.; Takizawa, M.; TIGANO, M.; REZNIK, E.; SHARMA, R.; CHALIGNE, R.; BAKER, D.; Pe'er, D.; THOMPSON, C.
10.1101/2024.10.15.618543 — molecular biology — Posted on 2024-10-17
2550 rRNA-specific antisense DNA and dsDNA trigger rRNA biogenesis and cause potent insecticidal effect on insect pest Coccus hesperidum L.
Oberemok, V. V.; Gal'chinsky, N. V.; Novikov, I. A.; Sharmagiy, A. K.; Yatskova, E. V.; Laikova, E. V.; Plugatar, Y. V.
10.1101/2024.10.15.618468 — molecular biology — Posted on 2024-10-17
2552 Embryological cellular origins and hypoxia-mediated mechanisms in PIK3CA-Driven refractory vascular malformations
Torii, S.; Nagaharu, K.; Nakanishi, N.; Usui, H.; Hori, Y.; Hirose, K.; Toyosawa, S.; Morii, E.; Narushima, M.; Kubota, Y.; Nakagawa, O.; Imanaka-Yoshida, K.; Maruyama, K.
10.1101/2024.10.16.618777 — molecular biology — Posted on 2024-10-17
2554 Targeted degradation of the HPV oncoprotein E6 reduces tumor burden in cervical cancer
Smalley, T. B.; Nicolaci, A.; Tran, K. C.; Lokhandwala, J.; Obertopp, N.; Matlack, J. K.; Miner, R. E.; Teng, M. M.; Pilon-Thomas, S.; Binning, J. M.
10.1101/2024.10.17.618959 — molecular biology — Posted on 2024-10-17
2557 Guided assembly of multispecies positive biofilms targeting undesirable bacteria
Gueneau, V.; Guillier, L.; Berdous, C.; Noirot-Gros, M.-F.; Jimenez, G.; Plateau, J.; Serror, P.; Castex, M.; Briandet, R.
10.1101/2024.10.16.618781 — microbiology — Posted on 2024-10-17
2558 Blood cultures at baseline and during persistent candidemia contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and virulence
Fleres, G.; Cheng, S.; Badrane, H.; Dupont, C. L.; Espinoza, J.; Abbey, D.; Driscoll, E.; Newbrough, A.; Hao, B.; Mansour, A.; Nguyen, M. H.; Clancy, C. J.
10.1101/2024.10.16.618724 — microbiology — Posted on 2024-10-17
2559 Multi-omics investigation of spontaneous T2DM macaque reveals gut microbiota promote T2DM by up-regulating the absorption of excess palmitic acid
Liu, X.; Yang, S.; Xie, Y.; Jiang, C.; Shang, K.; Luo, J.; Zhang, L.; Hu, G.; Liu, Q.; Yue, B.; Fan, Z.; He, Z.; Li, J.
10.1101/2024.10.17.618794 — microbiology — Posted on 2024-10-17
2560 Identification of SLC35A1 as an essential host factor for the transduction of multi-serotype recombinant adeno-associated virus (AAV) vectors
Zhang, X.; Hao, S.; Feng, Z.; Ning, K.; Kuz, C. A.; McFarlin, S.; Richart, D.; Cheng, F.; Zhang-Chen, A.; McFarlane, R.; Yan, Z.; Qiu, J.
10.1101/2024.10.16.618764 — microbiology — Posted on 2024-10-17
2561 SMC modulates ParB engagement in segregation complexes in Streptomyces
Pawlikiewicz, K.; Strzalka, A.; Majkowiski, M.; Dulawa-Kobeluszczyk, J.; Szafran, M.; Jakimowicz, D.
10.1101/2024.10.17.618854 — microbiology — Posted on 2024-10-17
2563 Trim7 does not have a role in the restriction of murine norovirus infection in vivo
Annaswamy Srinivas, M.; Pierce, L. R.; Olson, M. C.; Robertson, S. J.; Sturdevant, G. L.; Best, S. M.; Orchard, R. C.
10.1101/2024.10.17.618898 — microbiology — Posted on 2024-10-17
2567 Fluor NMR study of amino acid derived ligand to study TSPO
Duma, L.; Schneider, S.; Martinez, A.; Hachet, C.; Bihel, F.; Lacapere, J.-J.
10.1101/2024.10.14.618300 — biophysics — Posted on 2024-10-17
2569 Molecular mechanism of thyroxine transport by monocarboxylate transporters
Tassinari, M.; Tanzi, G.; Maggiore, F.; Groeneweg, S.; van Feest, F. S.; Freund, M.; Stavast, C. J.; Boniardi, I.; Pasqualato, S.; Visser, E. W.; Coscia, F.
10.1101/2024.10.17.618737 — biochemistry — Posted on 2024-10-17
2576 Investigating the genetic architecture of biotic stress response in stone fruit tree orchards under natural infections with a multi-environment GWAS approach
Serrie, M.; Segura, V.; Blanc, A.; Brun, L.; Dlalah, N.; Gilles, F.; Heurtevin, L.; Le-Pans, M.; Signoret, V.; Viret, S.; Audergon, J.-M.; Quilot, B.; Roth, M.
10.1101/2024.10.15.618428 — plant biology — Posted on 2024-10-17
2579 Bridging biomolecular modalities for knowledge transfer in bio-language models
Prakash, M.; Moskalev, A.; DiMaggio, P. A.; Combs, S.; Mansi, T.; Scheer, J.; Liao, R.
10.1101/2024.10.15.618385 — bioinformatics — Posted on 2024-10-17
2580 DEMINERS enables clinical metagenomics and comparative transcriptomic analysis by increasing throughput and accuracy of nanopore direct RNA sequencing
Song, J.; Lin, L.; Tang, C.; Chen, C.; Yang, Q.; Zhang, D.; Zhao, Y.; Wei, H.-c.; Linghu, K.; Xu, Z.; Chen, T.; He, Z.; Liu, D.; Zhong, Y.; Zhu, W.; Zeng, W.; Chen, L.; Song, G.; Chen, M.; Jiang, J.; Zhou, J.; Wang, J.; Chen, B.; Ying, B.; Wang, Y.; Geng, J.; Lin, J.-w.; Chen, L.
10.1101/2024.10.15.618384 — bioinformatics — Posted on 2024-10-17
2582 Knowledge Graphs and Explainable AI for Drug Repurposing on Rare Diseases
Perdomo-Quinteiro, P.; Wolstencroft, K.; Roos, M.; Queralt-Rosinach, N.
10.1101/2024.10.17.618804 — bioinformatics — Posted on 2024-10-17
2584 Chromosome-scale assembly and annotation of the wildwheat relative Aegilops comosa
Li, H.; Rehman, S. u.; Song, R.; Qiao, L.; Hao, X.; Zhang, J.; Li, K.; Hou, L.; Hu, W.; Wang, L.; Chen, S.
10.1101/2024.10.15.618371 — genomics — Posted on 2024-10-17
2585 Harnessing Global HLA Data for Enhanced Patient Matching in iPSC Haplobanks
Maiers, M.; Sullivan, S.; McClain, C.; Leonhard-Melief, C.; Turner, M. L.; Turner, D.
10.1101/2024.10.15.618361 — genetics — Posted on 2024-10-17
2587 14C-age of carbon used to grow fine roots reflects tree carbon status
Hilman, B.; Solly, E. F.; Hagedorn, F.; Kuhlmann, I.; Herrera-Ramirez, D.; Trumbore, S.
10.1101/2024.10.15.618388 — ecology — Posted on 2024-10-17
2588 Biomass allocation of trees in response to mono- and heterospecific neighbourhoods
Perles-Garcia, M. D.; Fichtner, A.; Haider, S.; Gu, H.; Bu, W.; Kunz, M.; Haerdtle, W.; von Oheimb, G.
10.1101/2024.10.15.618432 — ecology — Posted on 2024-10-17
2589 Spatial proteomics of Onchocerca volvulus with pleomorphic neoplasms shows local and systemic dysregulation of protein expression
Di Maggio, L. S.; Fischer, K.; Rosa, B. A.; Yates, D.; Cho, B.-K.; Lukowski, J.; Zamacona Calderon, A.; Son, M.; Goo, Y. A.; Opoku, N. O.; Weil, G. J.; Mitreva, M.; Fischer, P. U.
10.1101/2024.10.15.618383 — molecular biology — Posted on 2024-10-17
2590 Understanding the mechanisms underlying the lack of response to Janus kinase inhibition in ulcerative colitis
Melon-Ardanaz, E.; Veny, M.; Corraliza, A. M.; Garrido-Trigo, A.; Gudino, V.; Sanzo-Machuca, A.; Buendia, M.; Esteller, M.; Rodrigo, M.; Masamunt, M. C.; Giner, A.; Ordas, I.; Fernandez-Clotet, A.; Caballol, B.; Corbi, A. L.; Verstockt, B.; Vermeire, S.; Panes, J.; Ricart, E.; Salas, A.
10.1101/2024.10.17.618410 — immunology — Posted on 2024-10-17
2593 Outdoor Air Pollution Relates to Amygdala Subregion Volume and Apportionment in Early Adolescents
Morrel, J.; Overholtzer, L. N.; Sukumaran, K.; Cotter, D. L.; Cardenas-Iniguez, C.; Tyszka, J. M.; Schwartz, J.; Hackman, D. A.; Chen, J.-C.; Herting, M.
10.1101/2024.10.14.617429 — neuroscience — Posted on 2024-10-17
2594 A Cortical Microcircuit for Region-Specific Credit Assignment in Reinforcement Learning
Chevy, Q.; Szadai, Z.; Hertäg, L.; Moll, M.; Gibson, E. T.; Costa, R. P.; Kepecs, A.
10.1101/2024.10.15.618337 — neuroscience — Posted on 2024-10-17
2596 Detecting single motor-unit activity in magnetomyography
Noury, N.; Marquetand, J.; Hartwig, S.; Middelmann, T.; Broser, P.; Siegel, M.
10.1101/2024.10.15.618402 — neuroscience — Posted on 2024-10-17
2598 APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics
Ellis, D. S.; Watanabe, K.; Wilmanski, T.; Lustgarten, M. S.; Ardisson Korat, A. V.; Hadlock, J. J.; Fiehn, O.; Sebastiani, P.; Price, N. D.; Hood, L.; Magis, A. T.; Evans, S. J.; Pflieger, L.; Lovejoy, J. C.; Gibbons, S. M.; Funk, C. C.; Baloni, P.; Rappaport, N.
10.1101/2024.10.17.618322 — systems biology — Posted on 2024-10-17
2601 Mice with Reduced PAR4 Reactivity show Decreased Venous Thrombosis and Platelet Procoagulant Activity
Knauss, E. A.; Guci, J.; Luc, N.; Disharoon, D.; Huang, G. H.; Sen Gupta, A.; Nieman, M. T.
10.1101/2024.10.14.617127 — physiology — Posted on 2024-10-17
2605 Annotating full-scan MS data using tandem MS libraries
Xing, S.; Charron-Lamoureux, V.; El Abiead, Y.; Dorrestein, P. C.
10.1101/2024.10.14.618269 — bioinformatics — Posted on 2024-10-17
2607 KinPFN: Bayesian Approximation of RNA FoldingKinetics using Prior-Data Fitted Networks
Scheuer, D.; Runge, F.; Franke, J. K. H.; Wolfinger, M. T.; Flamm, C.; Hutter, F.
10.1101/2024.10.15.618378 — bioinformatics — Posted on 2024-10-17
2613 Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges
Hegde, S.; Akhter, S.; Tang, Z.; Qi, C.; Yu, C.; Lewicka, A.; Liu, Y.; Koirala, K.; Reibarkh, M.; Battaile, K. P.; Cooper, A.; Lovell, S.; Holmstrom, E. D.; Wang, X.; Piccirilli, J. A.; Gao, Q.; Miao, Y.; Wang, J.
10.1101/2024.10.14.618236 — biochemistry — Posted on 2024-10-17
2616 Genetic instrumental variable framework for assessing relevance of in-vitro cellular phenotypes to organism-level phenotypes
Howe, L. J.; Aulchenko, Y.; Cortes, A.; Esparza Gordillo, J.; Johnson, T.; Richardson, T. G.; Sanseau, P.; Scott, R. A.; Seaton, D. D.
10.1101/2024.10.17.618648 — genetics — Posted on 2024-10-17
2620 Virological characteristics of the SARS-CoV-2 XEC variant
Kaku, Y.; Okumura, K.; Kawakubo, S.; Uriu, K.; Chen, L.; Kosugi, Y.; Uwamino, Y.; Begum, M. M.; Leong, S.; Ikeda, T.; Sadamasu, K.; Asakura, H.; Nagashima, M.; Yoshimura, K.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.
10.1101/2024.10.16.618773 — microbiology — Posted on 2024-10-17
2621 Genetic removal of Nlrp3 protects against sporadic and R345W Efemp1-induced basal laminar deposit formation
Ortega, A. J.; Daniel, S.; Renwick, M.; Kambhampati, P.; Thompson, K. N.; Collier, G. E.; Baker, E. L.; Zaki, H.; Hulleman, J. D.
10.1101/2024.10.14.618289 — immunology — Posted on 2024-10-17
2622 Mindfulness training impacts brain network dynamics linked to stress response in young adolescents.
Gaviria, J.; Celen, Z.; Peek, L.; Magnus, M.; Brosset, S.; Vuilleumier, P.; Van De Ville, D.; Merglen, A.; Klauser, P.; Piguet, C.
10.1101/2024.10.16.616959 — neuroscience — Posted on 2024-10-17
2625 Microbially produced bile acids are associated with high levels of IgG autoantibodies and worse mental wellbeingin fibromyalgia subjects
Jakobsson, J. E.; Carlsson, H.; Erngren, I.; Menezes, J.; Krock, E.; Hunt, M. A.; Tour Sohlin, J.; Al-Grety, A.; Sandor, K.; Kosek, E.; Svensson, C. I.; Kultima, K.
10.1101/2024.10.17.618791 — neuroscience — Posted on 2024-10-17
2626 An Extensive Atlas of Proteome and Phosphoproteome Turnover Across Mouse Tissues and Brain Regions
Li, W.; Dasgupta, A.; Yang, K.; Wang, S.; Hemandhar-Kumar, N.; Yarbro, J. M.; Hu, Z.; Salovska, B.; Fornasiero, E. F.; Peng, J.; Liu, Y.
10.1101/2024.10.15.618303 — systems biology — Posted on 2024-10-17
2630 Integrated single cell functional-proteomic profiling of human skeletal muscle reveals a shift in cellular specificity in nemaline myopathy
Seaborne, R. A. E.; Moreno, R.; Laitila, J.; Lewis, C.; Savoure, L.; Zanoteli, E.; Lawlor, M.; Jungbluth, H.; Deshmukh, A. S.; Ochala, J.
10.1101/2024.10.17.618209 — physiology — Posted on 2024-10-17
2631 Advantage of the F(ab)'2 fragment over IgG for RIT and PRIT
Tabaja, Z. E.; Diab, M.; Nguyen, F.; Sai-Maurel, C.; Pecorari, F.; Lambot, S.; Davodeau, F.
10.1101/2024.10.16.617029 — cancer biology — Posted on 2024-10-17
2632 A novel combination of CDK4/6 and PI3K inhibitors exhibits highly synergistic activity and translational potential in Ewing sarcoma.
De Los Santos, M. A. I. C.; Gloege, H. F.; Shen, M.; Heaslip, C. O.; Aguilar-Quintero, A.; McDannel, B.; Tanhaemami, M.; Meyer, S.; Klega, K.; Zhang, Y.-Q.; Shulman, D. S.; DuBois, S. G.; Hall, M.; Blandin, A.-F.; Crompton, B. D.
10.1101/2024.10.14.618327 — cancer biology — Posted on 2024-10-17
2637 Circulation of Klebsiella pneumoniae strains between the termites, chimpanzees and humans
Houmenou, C. T.; Sarr, H.; DIENE, S. M.; Kacel, I.; Sokhna, C.; Fenollar, F.; Mediannikov, O.
10.1101/2024.10.14.618212 — bioinformatics — Posted on 2024-10-17
2638 Domain Specific AI Segmentation of IMPDH2 Rod/Ring Structures in Mouse Embryonic Stem Cells
Ball, S. T. M.; Hennessy, M. J.; Tan, Y.; Hoettges, K. F.; Perkins, N. D.; Wilkinson, D. J.; White, M. R. H.; Zheng, Y.; Turner, D. A.
10.1101/2024.10.16.617897 — bioinformatics — Posted on 2024-10-17
2639 Synthesis and characterization of chloroquine-modified albumin-binding siRNA-lipid conjugates for improved intracellular delivery and gene silencing in cancer cells
Lo, J. H.; Gbur, E. F.; Francini, N.; Ma, J.; Sorets, A. G.; Fletcher, R. B.; Yu, F.; D'Arcy, R.; Oltman, C. G.; Uddin, M. J.; Duvall, C. L.
10.1101/2024.10.14.618042 — bioengineering — Posted on 2024-10-17
2642 eQTL in diseased colon tissue identifies novel target genes associated with IBD
Nishiyama, N. C.; Silverstein, S.; Darlington, K.; Kennedy Ng, M. M.; Clough, K. M.; Bauer, M.; Beasley, C.; Bharadwaj, A.; Ganesan, R.; Kapadia, M. R.; Lau, G.; Lian, G.; Rahbar, R.; Sadiq, T. S.; Schaner, M. R.; Stem, J.; Friton, J.; Faubion, W. A.; Sheikh, S. Z.; Furey, T. S.
10.1101/2024.10.14.618229 — genomics — Posted on 2024-10-17
2643 Detection and full genome sequencing of a Deltacoronavirus and other bird associated viruses from feces of the kelp gull (Larus dominicanus) sampled at the South Shetland Islands Antarctica.
Gomes, F.; da Silva, A. c.; Resende, P. C.; Prado, T.; Da Silva, L. C.; Degrave, W.; Magalhaes, M.; Dias, Y. J.; Appolinario, L. R.; Vivioni, A.; Siqueira, M.; Brandao, M. L.; Wallau, G. d. L.; Ogrzewalska, M.
10.1101/2024.10.14.618326 — genomics — Posted on 2024-10-17
2644 Epigenetic and 3D genome reprogramming during the aging of human hippocampus
Zemke, N.; Lee, S.; Mamde, S.; Yang, B.; Berchtold, N.; Garduno, M.; Indralingam, H.; Bartosik, W.; Lau, P.; Dong, K.; Yang, A.; Tani, Y.; Chen, C.; Zeng, Q.; Ajith, V.; Tong, L.; Seng, C.; Li, D.; Wang, T.; Xu, X.; Ren, B.
10.1101/2024.10.14.618338 — genomics — Posted on 2024-10-17
2647 Lineage-aware evolutionary analysis of hepatitis C virus within-host dynamics
Zhao, L.; Hall, M.; Giridhar, P.; Ghafari, M.; Kemp, S.; Chai, H.; Klenerman, P.; Barnes, E.; Ansari, M. A.; Lythgoe, K. A.
10.1101/2024.10.15.617766 — evolutionary biology — Posted on 2024-10-17
2650 A parasite-inclusive food web for the California rocky intertidal zone
Zilz, Z. L.; Hascall, E.; DiBartolo, A.; Flores, D.; Cameron, S.; Orli, J.; Kuris, A.
10.1101/2024.10.14.618335 — ecology — Posted on 2024-10-17
2651 Saving the Dinaric lynx: multidisciplinary monitoring and stakeholder engagement support large carnivore restoration in human-dominated landscape
Krofel, M.; Flezar, U.; Cerne, R.; Hocevar, L.; Konec, M.; Majic Skrbinsek, A.; Skrbinsek, T.; Wilson, S.; Bele, B.; Crtalic, J.; Gomercic, T.; Hvala, T.; Kubala, J.; Kvapil, P.; Mavec, M.; Molinari-Jobin, A.; Molinari, P.; Pazhenkova, E.; Potocnik, H.; Sin, T.; Sindicic, M.; Toplicanec, I.; Oliveira, T.
10.1101/2024.10.15.617164 — ecology — Posted on 2024-10-17
2652 Molecular basis of interchain disulfide-bond formation in BMP-9 and BMP-10
Schwartze, T. A.; Morosky, S. A.; Rosato, T. L.; Henrickson, A.; Lin, G.; Hinck, C. S.; Taylor, A. B. A.; Olsen, S. K.; Calero, G.; Demeler, B.; Roman, B. L.; Hinck, A. P. H. P.
10.1101/2024.10.14.618187 — molecular biology — Posted on 2024-10-17
2653 Microbial iCLIP2: Enhanced mapping of RNA-Protein interaction by promoting protein and RNA stability
Stoffel, N. K.; Sankaranarayanan, S.; Muentjes, K.; Koertel, N.; Busch, A.; Zarnack, K.; Koenig, J.; Feldbruegge, M.
10.1101/2024.10.15.618220 — molecular biology — Posted on 2024-10-17
2654 Spontaneous formation of different forms of alpha-synuclein fibrils from a recombinant protein
Egorov, V. V.; Grudinina, N. A.; Polyakov, D. S.; Zabrodskaya, Y. A.; Gavrilova, N. V.; Shavlovsky, M. M.
10.1101/2024.10.15.617481 — molecular biology — Posted on 2024-10-17
2657 m6A-mediated epi-transcriptomic dysregulation underlies synaptic dysfunction in fragile X syndrome
Guo, Z.; Lu, L.; Sarkar, A. K.; Dao, L.; Liu, Y.; Ma, C.; Thwin, P. H.; Chang, X.; Yoshida, G.; Li, A.; Wang, C.; Westerkamp, G.; Schmitt, L.; Chelsey, M.; Stephanie, M.; Zhao, Y.; Liu, Y.; Wang, X.; Zhu, L.-Q.; Liu, D.; Tchieu, J.; Miyakoshi, M.; Zhu, H.; Gross, C.; Pedapati, E.; Salomonis, N.; Erickson, C.
10.1101/2024.10.14.618205 — neuroscience — Posted on 2024-10-17
2658 Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
Fricke, M.; Mechel, A.; Twellsieck, B.; Grein, J. M.; Cima-Omori, M.-S.; Zweckstetter, M.; Holzbaur, E.; Boecker, C. A.
10.1101/2024.10.14.618089 — neuroscience — Posted on 2024-10-17
2662 Apoptosis is increased in cortical neurons of female Marfan Syndrome mice
Esfandiarei, M.; Anwar, F.; Nuthi, M.; Harrison, A.; Eunice Barrameda, M.; Curry-Koski, T. M.; Pull, K.; Currier Thomas, T.; Jadavji, N. M.
10.1101/2024.10.14.618278 — neuroscience — Posted on 2024-10-17
2667 Integration of the DD-genome reshapes gene transcription, chromatin architecture and metabolome of allohexaploid wheat leading to enhanced adaptability
Liu, Y.; Zhu, T.; Zhou, X.; Chen, W.; He, C.; Wang, X.; Chen, C.; Wei, J.; Lan, C.; Liu, M.; Su, H.; Li, Q.; Hu, X.; Bi, S.; Ouyang, W.; Li, X.; Mao, H.; Kishi, M.; Kaufmann, K.; Fernie, A. R.; Chen, D.; Yan, W.
10.1101/2024.10.15.618349 — plant biology — Posted on 2024-10-17
2668 Female Specific Restrictive Cardiomyopathy and Metabolic Dysregulation in transgenic mice expressing a Peptide of the Amino-Terminus of GRK2
Bledzka, K. M.; Manaserh, I. H.; Ifft, A. D.; Rennison, J. H.; Bohacek, M.; Vasiliauskas, K. M.; Grondolsky, J.; Ampong, I.; Van Wagoner, D. R.; Schumacher, S. M.
10.1101/2024.10.14.618348 — physiology — Posted on 2024-10-17
2669 Torsion is a Dynamic Regulator of DNA Replication Stalling and Reactivation
Jia, X.; Gao, X.; Zhang, S.; Inman, J. T.; Hong, Y. T.; Singh, A.; Patel, S. S.; Wang, M. D.
10.1101/2024.10.14.618227 — biophysics — Posted on 2024-10-17
2671 Simulating 3D refractive index distributions of suspended cells
Borrelli, F.; Pirone, D.; Miccio, L.; Memmolo, P.; Ferraro, P.; Bianco, V.
10.1101/2024.10.14.618263 — biophysics — Posted on 2024-10-17
2672 A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities
Dannenberg, R. L.; Cardina, J. A.; Washington, H.; Gao, S.; Greenberg, M. M.; Hedglin, M.
10.1101/2024.10.14.618244 — biochemistry — Posted on 2024-10-17
2675 Heat Stress on the brown Seaweed Ascophyllum nodosum: differential population sensitivity to future climate.
Pereira, L. F.; Arenas, F.; Seabra, R.; Silva, R.; Monteiro, C.; Pereira, J.; Vale, C.; Serodio, J.; Frankenback, S.; Ghiglione, V.; Ribeiro, P.; Lima, F. P.
10.1101/2024.10.14.618208 — ecology — Posted on 2024-10-17
2678 Modeling Attention and Binding in the Brain through Bidirectional Recurrent Gating
Salehinajafabadi, S.; Lei, J.; Benjamin, A. S.; Muller, K. R.; Kording, K. P.
10.1101/2024.09.09.612033 — neuroscience — Posted on 2024-10-17
2681 An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4
Bhaduri, S. E.; Braza, M. K. E.; Stanchev, S.; Bach, K.; Tauber, M.; Al-Bawab, R.; Liu, L. J.; Trujillo, D. F.; Solorio-Kirpichyan, K.; Srivastava, A.; Sanlley-Hernandez, J.; O'Donoghue, A. J.; Lemberg, M. K.; Amaro, R. E.; Strisovsky, K.; Neal, S. E.
10.1101/2024.10.13.618094 — biochemistry — Posted on 2024-10-17
2688 Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
Scott, H. C.; Philpott, M.; Berridge, G.; Yu, Z.; O'Brien, D. P.; Becker, C.; Lindgren, C.; Opperman, U.; Mueller, J.; Fritsch, M.; Pinto-Fernandez, A.; Kessler, B. M.
10.1101/2024.10.14.618228 — biochemistry — Posted on 2024-10-17
2690 An analysis of RNA quality metrics in human brain tissue
Tian, J.; Lam, T.; Ross, S.; Ciener, B.; Leskinen, S.; Sivakumar, S.; Bennett, D. A.; Menon, V.; McKhann, G. M.; Runnels, A.; Teich, A.
10.1101/2024.10.14.618253 — neuroscience — Posted on 2024-10-17
2697 Thioether-functionalized cellulose for the fabrication of oxidation-responsive biomaterial coatings and films
DuBois, E. M.; Herrema, K. E.; Simkulet, M. G.; Hassan, L. F.; O'Connor, P. R.; Sen, R.; O'Shea, T. M.
10.1101/2024.07.24.604973 — bioengineering — Posted on 2024-10-17
2699 The Taiwan Precision Medicine Initiative: A Cohort for Large-Scale Studies
Yang, H.-C.; Kwok, P.-Y.; Li, L.-H.; Liu, Y.-M.; Jong, Y.-J.; Lee, K.-Y.; Wang, D.-W.; Tsai, M.-F.; Yang, J.-H.; Chen, C.-H.; Yeh, E.-C.; Wei, C.-y.; Fann, C. S.- J.; Huang, Y.-T.; Chen, C.-W.; Lee, Y.-J.; Chu, S.-K.; Ho, C.-h.; Yang, C.-S.; Lee, Y. L.; Chen, H.-H.; Hou, M.-C.; Chiou, J.-F.; Yang, S.-F.; Wang, C.-H.; Huang, C.-Y.; Chiu, K.-M.; Chen, M.; Chiang, F.-T.; Lee, S.-L.; Chen, S.-S.; Yao, W.-J.; Chien, C.-C.; Lin, S.-Y.; Chang, F.-P.; Ho, H.-L.; Yeh, Y.-C.; Tseng, W.-C.; Lin, M.-H.; Chang, H.-T.; Tseng, L.-M.; Liang, W.-Y.; Chen, P. C.-H.; Hang, J.-F.; Lin, S.-C.; Chan, Y.-J.; Kuo, Y.
10.1101/2024.10.14.616932 — genetics — Posted on 2024-10-17
2700 Outer membrane changes enable evolutionary escape from bacterial predation
Mridha, S.; Loose, S.-L.; Mattmann, O. C.; Isele, S.; Kuemmerli, R.; Huwiler, S. G.
10.1101/2024.09.27.615459 — evolutionary biology — Posted on 2024-10-17
2702 Increase of tropical seabirds (Sula) in the California Current Ecosystem with warmer ocean conditions
Russell, T. M.; Pereksta, D. M.; Tietz, J. R.; Vernet, M.; Jahncke, J.; Ballance, L. T.
10.1101/2024.10.14.618240 — ecology — Posted on 2024-10-17
2703 SON-dependent nuclear speckle rejuvenation alleviates proteinopathies
Dion, W.; Tao, Y.; Chambers, M.; Zhao, S.; Arbuckle, R. K.; Sun, M.; Kubra, S.; Jamal, I.; Nie, Y.; Ye, M.; Larsen, M. B.; Camarco, D.; Ickes, E.; DuPont, C.; Wang, H.; Wang, B.; Liu, S.; Pi, S.; Chen, B. B.; Chen, Y.; Chen, X.; Zhu, B.
10.1101/2024.04.18.590103 — cell biology — Posted on 2024-10-17
2705 Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop
Willemsen, L.; Lee, J.; Shinde, P.; Soldevila, F.; Aoki, M.; Orfield, S.; Kojima, M.; Antunes, R. d. S.; Sette, A.; Peters, B.
10.1101/2024.08.05.606623 — immunology — Posted on 2024-10-17
2708 Highly expressed cell wall genes contribute to robustness of sepal size
Hartasanchez, D. A.; Dumond, M.; Dubrulle, N.; Moneger, F.; Boudaoud, A. A.
10.1101/2024.10.14.618238 — plant biology — Posted on 2024-10-17
2709 Bringing Attomolar Detection to the Point-of-Care with Nanopatterned DNA Origami Nanoantennas
Yaadav, R.; Trofymchuk, K.; Dass, M.; Behrendt, V.; Hauer, B.; Schuetz, J.; Close, C.; Scheckenbach, M.; Ferrari, G.; Maeurer, L.; Sebina, S.; Glembockyte, V.; Liedl, T.; Tinnefeld, P.
10.1101/2024.10.14.618183 — biophysics — Posted on 2024-10-17
2711 The role of RNA in the nanoscale organization of alpha-synuclein phase separation
Zappone, S.; Perego, E.; Rupert, J.; Zacco, E.; Slenders, E.; Tartaglia, G. G.; Vicidomini, G.
10.1101/2024.09.03.610813 — biophysics — Posted on 2024-10-17
2712 A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV
Sajadi, M.; Abbasi, A.; Rikhtegaran Tehrani, Z.; Siska, C.; Clark, R.; Chi, W.; Seaman, M. S.; Mielke, D.; Wagh, K.; Liu, Q.; Jumpa, T.; Ketchem, R. R.; Nguyen, D. N.; Tolbert, W. D.; Pierce, B. G.; Atkinson, B.; Deming, D.; Sprague, M.; Asakawa, A.; Ferrer, D.; Dunn, Y.; Calvillo, S.; Yin, R.; Guest, J. D.; Korber, B.; Mayer, B. T.; Sato, A. H.; Ouyang, X.; Foulke, S.; Habibzadeh, P.; Karimi, M.; Aslanabadi, A.; Hojabri, M.; Saadat, S.; Zareidoodeji, R.; Kedzior, M.; Pozharski, E.; Heredia, A.; Montefiori, D.; Ferrari, G.; Pazgier, M.; Lewis, G. K.; Jardine, J. G.; Lusso, P.; Devico, A.
10.1101/2024.10.14.618178 — bioengineering — Posted on 2024-10-17
2713 How the microbiome liberates iron from heme
Nath, A. K.; da Silva, R. R.; Akpoto, E.; Adedoyin, V.; Dlakic, M.; Lawrence, C. M.; DuBois, J.
10.1101/2024.10.14.618232 — biochemistry — Posted on 2024-10-17
2716 Depleting trafficking regulator CASK promotes intercalated disc organization and ventricular function
Blandin, C. E.; Dilanian, G.; Fontaine, V.; Mougenot, N.; Gravez, B.; Bobin, P.; Duboscq-Bidot, L.; Farhi, D.; Chardonnet, S.; Nadaud, S.; Sanchez-Alonzo, J. L.; Shevchuk, A.; Gorelik, J.; Gandjbakhch, E.; Hatem, S. N.; Villard, E.; Balse, E.
10.1101/2024.10.14.618172 — physiology — Posted on 2024-10-17
2717 OpenASO: RNA Rescue--designing splice-modulating antisense oligonucleotides through community science
Tse, V.; Guiterrez, M.; Townley, J.; Romano, J.; Pearl, J.; Chacaltana, G.; Players, E.; Das, R.; Sanford, J.; Stone, M.
10.1101/2024.10.15.618608 — biochemistry — Posted on 2024-10-17
2718 Functional study of Phaeodactylum tricornutum Seipin homolog highlights unique features of lipid droplets biogenesis in diatoms.
Le Moigne, D.; Richard, F.; Albrieux, C.; Mahieu, M.; Arrighi, M.; Si Larbi, G.; jouneau, P.-H.; Gros, V.; Louwagie, M.; Roy, S.; Amari, C.; Carletti, M.; Bonnarde, R.; Gong, Y.; Pan, Y.; Hu, H.; Bastien, O.; Jouhet, J.; Amato, A.; Marechal, E.; Salvaing, J.
10.1101/2024.10.11.617903 — plant biology — Posted on 2024-10-17
2721 DDX41 dissolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death
Bi, H.; Ren, K.; Wang, P.; Li, E.; Han, X.; Wang, W.; Yang, J.; Aydemir, I.; Tao, K.; Godley, L.; Liu, Y.; Shukla, V.; Bartom, E.; Tang, Y.; Blanc, L.; Sukhanova, M.; Ji, P.
10.1101/2024.10.14.617891 — cancer biology — Posted on 2024-10-17
2722 Replicating retroviral delivery of an IL-15 superagonist improves antitumor immunity and long-term survival in poorly immunogenic glioblastoma models
Haddad, A. F.; Saha, A.; Spatz, J.; Collins, S.; Lovalvo, I.; Gill, S.; Montoya, M. L.; Shukla, P.; Hong, J.; Wang, E.; Chuntova, P.; Lad, M.; Chalif, E.; Kasahara, N.; Aghi, M. K.
10.1101/2024.10.14.618095 — cancer biology — Posted on 2024-10-17
2724 Identification of RING E3 pseudoligases in the TRIM protein family
Dudley-Fraser, J.; Esposito, D.; McPhie, K.; Morley-Williams, C.; Auchynnikava, T.; Rittinger, K.
10.1101/2024.10.15.614675 — biochemistry — Posted on 2024-10-17
2728 Sugar-rich foods exacerbate antibiotic-induced microbiome injury
Dai, A.; Adintori, P. A.; Funnell, T.; Jogia, W. P.; Fei, T.; Waters, N. R.; Rangesa, M.; Ballweg, A.; Gipson, B.; Raj, S.; Hayase, E.; Markey, K. A.; Burgos da Silva, M.; Miltiadous, O.; Brambilla, C. Z.; Buchan, M. L.; Peets, T.; Gradissimo, A.; Smith, N.; Katsamakis, Z.; Warren, A.; Amoretti, L. A.; Duan, C.; Zhang, C.; Matheis, F.; Sullivan, A. P.; Slingerland, J. B.; Clurman, A.; Brereton, D. G.; Giardina, P. A.; Gomes, A. L. C.; Johnson, A. J.; Knights, D.; Jenq, R. R.; Perales, M.-A.; Giralt, S. A.; Schluter, J.; van den Brink, M. R. M.; Peled, J.
10.1101/2024.10.14.617881 — microbiology — Posted on 2024-10-17
2729 Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland
de Freitas Almeida, G. M.; Leppänen, M.; de Azevedo, B. L.; Abrahao, J. S.; Andreani, J.; Zabeo, D.; Ravantti, J. J.; Arriaga, I.; Abrescia, N. G.; Sundberg, L.-R.
10.1101/2024.10.16.618641 — microbiology — Posted on 2024-10-17
2730 Three cytochrome P450 enzymes catalyse the formation of furanoclerodane precursors in Salvia spp.
Lin, R.; Li, H.; Xiao, Y.; Wang, Z.; Liu, L.; Saalbach, G.; Martins, C.; Martin, C.; Tatsis, E.
10.1101/2024.10.13.618057 — plant biology — Posted on 2024-10-17
2731 Cystobactamid off-target profiling reveals favorable safety, superoxide reduction, and SCARB1 inhibition in eukaryotes
Risch, T.; Hellwinkel, B.; Mostert, D.; Kany, A. M.; Solga, D.; Seedorf, T.; Heimann, D.; Hoppstädter, J.; Kohnhäuser, D.; Hilgers, J.-S.; Fries, F.; Deschner, F.; Brönstrup, M.; Kirschning, A.; Sieber, S. A.; Pietschmann, T.; Kiemer, A. K.; Herrmann, J.; Müller, R.
10.1101/2024.10.10.617689 — pharmacology and toxicology — Posted on 2024-10-17
2733 Transcriptomic bases of within- and trans-generational predator-induced plasticity in the freshwater snail Physa acuta
Dejeux, L.; Saclier, N.; Tariel-Adam, J.; Hoareau, M.; Lefebure, T.; Konecny, L.; Plenet, S.; Luquet, E.
10.1101/2024.10.16.618730 — evolutionary biology — Posted on 2024-10-17
2734 Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction
Hwang, S.-Y.; Jeon, K.-H.; Lee, H.-J.; Moon, I.; Jung, S.; Kim, S.-A.; Jo, H.; Park, S.; Ahn, M.; Kwak, S.-Y.; Na, Y.; Kwon, Y.
10.1101/2024.03.01.583029 — pharmacology and toxicology — Posted on 2024-10-17
2736 The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain
Haas-Neill, L.; Meneksedag-Erol, D.; Chaudhry, A.; Novoselova, M.; Ashraf, Q. F.; de Araujo, E. D.; Wilson, D. J.; Rauscher, S.
10.1101/2024.09.09.612134 — biophysics — Posted on 2024-10-17
2739 Functional characterization of luciferase in a brittle star indicates parallel evolution influenced by genomic availability of haloalkane dehalogenase
Lau, E. S.; Majerova, M.; Hensley, N. M.; Mukherjee, A.; Vasina, M.; Pluskal, D.; Damborsky, J.; Prokop, Z.; Delroisse, J.; Bayaert, W.-S.; Parey, E.; Oliveri, P.; Marletaz, F.; Marek, M.; Oakley, T. H.
10.1101/2024.10.14.618359 — evolutionary biology — Posted on 2024-10-17
2741 White Matter Microstructural Alterations in Autism Localized with Bundle Analytics
Kim, G. S.; Chandio, B. Q.; Benavidez, S. M.; Thompson, P. M.; Lawrence, K. E.
10.1101/2024.10.16.618731 — neuroscience — Posted on 2024-10-17
2742 Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine
Schoenle, A.; Guiglielmoni, N.; Mainz, T.; Greve, C.; Hamadou, A. B.; Heermann, L.; Borcherding, J.; Waldvogel, A.-M.
10.1101/2024.04.22.590508 — genomics — Posted on 2024-10-17
2743 Developmental pathways underlying sexual differentiation in a U/V sex chromosome system
Liesner, D.; Cossard, G.; Zheng, M.; Godfroy, O.; Barrera-Redondo, J.; Haas, F. B.; Coelho, S. M.
10.1101/2024.02.09.579736 — developmental biology — Posted on 2024-10-17
2744 Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants
Tiwari, M.; Gas-Pascual, E.; Goyal, M.; Popov, M.; Matsumoto, K.; Grafe, M.; Graf, R.; Haltiwanger, R. S.; Olszewski, N. E.; Orlando, R.; Samuelson, J.; West, C. M.
10.1101/2024.10.15.618526 — cell biology — Posted on 2024-10-17
2745 A role for class I PAKs in the regulation of the excitability of the actin cytoskeleton.
Tyler, J. J.; Davidson, A.; Poxon, M. E.; Martinez, M. L.; Hume, P. J.; King, J. S.; Koronakis, V.
10.1101/2024.10.16.618394 — cell biology — Posted on 2024-10-17
2748 Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation
Baron, M.; Tagore, M.; Wall, P.; Zheng, F.; Barkley, D.; Yanai, I.; Yang, J.; Kiuru, M.; White, R.; Ideker, T.
10.1101/2023.09.19.558457 — systems biology — Posted on 2024-10-17
2749 A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness
Debnath, A. J.; Harencar, L.; Kucka, M.; Kovar, M.; Ivanisova, E.; Mistrikova, V.; Gazo, J.; Razna, K.
10.1101/2024.10.10.617604 — plant biology — Posted on 2024-10-17
2752 Simultaneous visualization of cells and marker genes from scRNA-seq studies
Bhattacharya, N.; Chakraborti, S.; Gupta, K.; Mittal, A.; Sinha, D.; Nelson, C. C.; Chakraborty, T.; Ahuja, G.; Sengupta, D.
10.1101/2022.12.27.521966 — bioinformatics — Posted on 2024-10-17
2759 A lipid signature of BAK-driven apoptotic pore formation
Uren, R. T.; Ritchie, M. E.; Wong, A. W.; Ludeman, J. P.; Uno, E.; Narayana, V. K.; De Souza, D. P.; Sviridov, D.; Kluck, R. M.
10.1101/2024.10.16.618570 — cell biology — Posted on 2024-10-17
2760 Intra-manchette transport employs both microtubule and actin tracks
Judernatz, J.; Perez Paneda, L.; Kadava, T.; Heck, A. J. R.; Zeev-Ben-Mordehai, T.
10.1101/2024.10.16.618660 — cell biology — Posted on 2024-10-17
2762 Modeling Compound Lipid Homeostasis Using Stable Isotope Tracing
Wessendorf-Rodriguez, K.; Ruchhoeft, M. L.; Ashley, E. L.; Galvez, H. M.; Murray, C. W.; Mcgregor, G.; Kambhampati, S.; Shaw, R. J.; Metallo, C. M.
10.1101/2024.10.16.618599 — cell biology — Posted on 2024-10-17
2765 Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria
Zhang, L.; Guan, Y.; Cheng, Y. Y.; Cokcetin, N. N.; Bottomley, A.; Robinson, A.; Harry, E.; van Oijen, A. M.; Su, Q. P.; Jin, D.
10.1101/2022.03.29.486198 — microbiology — Posted on 2024-10-17
2766 Role of dopamine in reward expectation and predictability during execution of action sequences
Magnard, R.; Cheng, Y.; Zhou, J.; Province, H.; Thiriet, N.; Janak, P. H.; Vandaele, Y.
10.1101/2024.10.16.618735 — neuroscience — Posted on 2024-10-17
2768 The restricted N-glycome of neurons is programmed during differentiation
Kiwimagi, K.; Noel, M.; Cetinbas, M.; Sadreyev, R.; Wang, L.; Smoller, J. W.; Cummings, R. D.; Weiss, R.; Mealer, R. G.
10.1101/2024.10.15.618477 — neuroscience — Posted on 2024-10-17
2769 Prefrontal orchestration: a cortical network for rodent motor inhibition
Jaeckel, Z.; Schwaderlapp, N.; Adzemovic, A.; Steenbergen, F.; Hardung, S.; Fuchs, K.; Leibold, C.; Zaitsev, M.; Diester, I.
10.1101/2024.10.16.618207 — neuroscience — Posted on 2024-10-17
2770 A protective role for the cerebellum in cognitive aging
d'Oleire Uquillas, F.; Sefik, E.; Seidlitz, J.; Merriman, J.; Zhang, V.; Cohen, J. D.; Romero-Garcia, R.; Warrier, V.; Bethlehem, R. A. I.; Alexander-Bloch, A. F.; Sepulcre, J.; Wang, S. S.- H.; Vannini, P.; Gomez, J.
10.1101/2024.10.15.618102 — neuroscience — Posted on 2024-10-17
2771 Structured dynamics in the algorithmic agent
Ruffini, G.; Castaldo, F.; Lopez-Sola, E.; Sanchez-Todo, R.; Vohryzek, J.
10.1101/2023.12.12.571311 — neuroscience — Posted on 2024-10-17
2773 Targeting the 3D genome by anthracyclines for chemotherapeutic effects
Tan, M.; Sun, S.; Liu, Y.; Perreault, A. A.; Phanstiel, D. H.; Dou, L.; Pang, B.
10.1101/2024.10.15.614434 — cancer biology — Posted on 2024-10-17
2777 KLHDC7B, a novel gene associated with age-related hearing loss in humans, is required for the maintenance of hearing in mice.
Kaufman, A. M.; Silver, B.; Donnianni, R. A.; Aguilar, C.; Niu, L.; Johnson, D.; Bullen, A.; Corona, A.; van Soldt, B. J.; Vora, N.; Batista, G.; Cortes-Burgos, L.; Copeland, J.; Fallah, E.; Zhang, N.; Lehmkuhl, M.; Cancelarich, S.; Campos, K.; Miani, D. D. B.; Mumphrey, J.; Croll, S. D.; Walls, J. R.; Germino, M.; Bowl, M. R.; Drummond, M. C.; Dawson, S. J.
10.1101/2024.10.14.618265 — genetics — Posted on 2024-10-17
2780 An increase in reactive oxygen species underlies neonatal cerebellum repair
Pakula, A.; El Nagar, S.; Bayin, S.; Christensen, J. B.; Stephen, D.; Reid, A.; Koche, R. P.; Joyner, A. L.
10.1101/2024.10.14.618368 — developmental biology — Posted on 2024-10-17
2781 HIV-1 infection is associated with depletion of germinal center B cells and a decrease in IgA+ plasma cells in the GI tract
Cossarini, F.; Shang, J.; Krek, A.; Al-taie, Z.; Hou, R.; Canales-Herrerias, P.; Tokuyama, M.; Tankelevich, M.; Tillowiz, A.; Jha, D.; Livanos, A.; Leyre, L.; Uzzan, M.; Martinez-Delgado, G.; Taylor, M. D.; Sharma, K.; Bourgonje, A. R.; Cruz, M.; Ioannou, G.; Dawson, T.; D'souza, D.; Kim-Schulze, S.; Ahmed, A.; Aberg, J. A.; Chen, B. K.; Gnjatic, S.; Polydorides, A. D.; Cerutti, A.; Argmann, C.; Vujkovic-Cvijin, I.; Suarez-Farinas, M.; Petralia, F.; Faith, J. J.; Mehandru, S.
10.1101/2024.05.17.590425 — immunology — Posted on 2024-10-17
2782 Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis
Mittl, K.; Hayashi, F.; Dandekar, R.; Schubert, R. D.; Gerdts, J.; Oshiro, L.; Loudermilk, R.; Greenfield, A. L.; Augusto, D. G.; Ramesh, A.; Tran, E.; Koshal, K.; Kizer, K.; Dreux, J.; Cagalingan, A.; Schustek, F.; Flood, L.; Moore, T.; Kirkemo, L. L.; Cooper, T.; Harms, M.; Gomez, R.; University of California, San Francisco MS-EPIC Team, ; Sibener, L.; Cree, B. A. C.; Hauser, S. L.; Hollenbach, J. A.; Gee, M.; Wilson, M. R.; Zamvil, S.; Sabatino, J. J.
10.1101/2024.09.07.611010 — immunology — Posted on 2024-10-17
2784 Blood-based Nano-QuIC: Inhibitor-resistant Detection of Seeding Activity in Patients Diagnosed with Parkinson Disease
Christenson, P. R.; Jeong, H.; Li, M.; Ahn, H.; Schmeichel, A. M.; Misra, P.; Li, D.; Savica, R.; Low, P. A.; Singer, W.; Larsen, P. A.; Park, H. Y.; Oh, S.-H.
10.1101/2023.08.09.552630 — neuroscience — Posted on 2024-10-17
2785 Spatial and network principles behind neural generation of locomotion
Komi, S.; Winther, A.; Houser, G.; Sorensen, R. J.; Larsen, S.; Bonfils, M.; Li, G.; Berg, R. W.
10.1101/2024.10.03.616472 — neuroscience — Posted on 2024-10-17
2786 BIBSNet: A Deep Learning Baby Image Brain Segmentation Network for MRI Scans
Hendrickson, T. J.; Reiners, P.; Moore, L. A.; Lundquist, J. T.; Fayzullobekova, B.; Perrone, A. J.; Lee, E. G.; Moser, J.; Day, T. K. M.; Alexopoulos, D.; Styner, M.; Kardan, O.; Chamberlain, T. A.; Mummaneni, A.; Caldas, H. A.; Bower, B.; Stoyell, S.; Martin, T.; Sung, S.; Fair, E.; Carter, K.; Uriarte-Lopez, J.; Rueter, A. R.; Yacoub, E.; Rosenberg, M. D.; Smyser, C. D.; Elison, J. T.; Graham, A.; Fair, D. A.; Feczko, E.
10.1101/2023.03.22.533696 — neuroscience — Posted on 2024-10-17
2788 Representations of stimulus meaning in the hippocampus
Biane, J. S.; Ladow, M. A.; Fan, A.; Choi, H. S.; Zhou, L. Z.; Hassan, S.; Apodaca-Montano, D. L.; Kwon, A. O.; Bratsch-Prince, J. X.; Kheirbek, M. A.
10.1101/2024.10.14.618280 — neuroscience — Posted on 2024-10-17
2791 Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites
Lawore, D. C.; Jena, S.; Berard, A. R.; Birse, K.; Lamont, A.; Mackelprang, R. D.; Noel-Romas, L.; Perner, M.; Hou, X.; Irungu, E.; Mugo, N.; Knodel, S.; Muwonge, T. R.; Katabira, E.; Hughes, S. M.; Levy, C.; Calienes, F. L.; Hladik, F.; Lingappa, J. R.; Burgener, A. D.; Green, L. N.; Brubaker, D. K.
10.1101/2024.10.10.616351 — systems biology — Posted on 2024-10-17
2792 Attentive graph neural network models for the prediction of blood-brain barrier permeability
Collins, J. W.; Ebrahimkhani, M.; Ramirez, D.; Abedi, M.; Philippe-Venec, L.; Cole, B. M.; Moore, B.; Nwankwo, J. O.
10.1101/2024.10.12.617907 — pharmacology and toxicology — Posted on 2024-10-17
2794 ProtEx: A Retrieval-Augmented Approach for Protein Function Prediction
Shaw, P.; Gurram, B.; Belanger, D.; Gane, A.; Bileschi, M. L.; Colwell, L. J.; Toutanova, K.; Parikh, A. P.
10.1101/2024.05.30.596539 — bioinformatics — Posted on 2024-10-17
2795 LMD: Cluster-Independent Multiscale Marker Identification in Single-cell RNA-seq Data
Li, R.; Qu, R.; Parisi, F.; Strino, F.; Lam, H.; Stanley, J. S.; Cheng, X.; Myung, P.; Kluger, Y.
10.1101/2023.11.12.566780 — bioinformatics — Posted on 2024-10-17
2796 Multi-physics simulations reveal hemodynamic impacts of patient-derived fibrosis-related changes in left atrial tissue mechanics
Gonzalo, A.; Augustin, C.; Bifulco, S. F.; Telle, A.; Chahine, Y.; Kassar, A.; Guerrero-Hurtado, M.; Duran, E.; Martinez-Legazpi, P.; Flores, O.; Bermejo, J.; Plank, G.; Akoum, N.; Boyle, P. M.; del Alamo, J. C.
10.1101/2024.05.29.596526 — bioengineering — Posted on 2024-10-17
2797 Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum
Evseeva, D.; Pecrix, Y.; Kucka, M.; Weiler, C.; Franzl, C.; Vlkova-Zlebkova, M.; Colombi, E.; Chan, Y. F.; Poussier, S.; Wicker, E.; McCann, H. C.
10.1101/2024.10.16.618685 — microbiology — Posted on 2024-10-16
2803 Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Groves, D.; Cunnison, R.; McMahon, A.; Fan, H.; Sharps, J.; Deng, A.; Keown, J. R.; Fodor, E.; Robb, N. C.
10.1101/2024.10.15.618435 — microbiology — Posted on 2024-10-16
2804 The major pathogen Haemophilus influenzae experiences pervasive recombination and purifying selection at local and global scales
MacAlasdair, N.; Pöntinen, A. K.; Ling, C.; Mallawaarachchi, S.; Thaipadungpanit, J.; Nosten, F. H.; Turner, C.; Bentley, S. D.; Croucher, N. J.; Turner, P.; Corander, J.
10.1101/2024.10.16.618562 — microbiology — Posted on 2024-10-16
2805 Genetic compatibility and ecological connectivity drive the dissemination of antibiotic resistance genes
Lund, D.; Parras-Molto, M.; Inda-Diaz, J. S.; Ebmeyer, S.; Larsson, D. G. J.; Johnning, A.; Kristiansson, E.
10.1101/2024.10.15.617735 — microbiology — Posted on 2024-10-16
2808 Fusobacterium necrophorum and Fusobacterium varium are commensal members of the bovine reproductive microbiota and may colonize calf prenatally
Kilama, J.; Dahlen, C. R.; Abbasi, M.; Shi, X.; Nagaraja, T. G.; Crouse, M. S.; Cushman, R. A.; Snider, A. P.; McCarthy, K.; Caton, J. S.; Amat, S.
10.1101/2024.10.15.618546 — microbiology — Posted on 2024-10-16
2811 Locus-specific chromatin proteomics using dCas-guided proximity labelling in Aspergillus nidulans.
Strauss, J.; Svoboda, T.; Schueller, A.; Niederdockl-Loibl, D.; Hummel, K.; Schlosser, S.; Razzazi-Fazeli, E.
10.1101/2024.10.15.618449 — molecular biology — Posted on 2024-10-16
2812 SARS-CoV-2 outbreak in lions, tigers and hyenas at Denver Zoo
Gallichotte, E. N.; Bashor, L.; Erbeck, K.; Croft, L.; Stache, K.; Long, J.; VandeWoude, S.; Johnson, J.; Pabilonia, K.; Ebel, G.
10.1101/2024.10.14.617443 — microbiology — Posted on 2024-10-16
2813 The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus
Rosendal, E.; Bisikalo, K.; Willekens, S. M. A.; Lindgren, M.; Holoubek, J.; Svoboda, P.; Lappalainen, A.; Konighofer, E.; Mirgorodskaya, E.; Norden, R.; Morini, F.; Rosenbaum, W.; Ruzek, D.; Ahlgren, U.; Anastasina, M.; Merits, A.; Butcher, S. J.; Nilsson, E.; Overby, A. K.
10.1101/2024.10.16.618642 — microbiology — Posted on 2024-10-16
2817 Strong segregation promotes self-destructive cooperation
Wen, L.; Bai, Y.; Lan, Y.; Shen, Y.; She, X.; Dong, P.; Wang, T.; Fu, X.; Huang, S.
10.1101/2024.10.15.618393 — microbiology — Posted on 2024-10-16
2818 Role of a single MCP in evolutionary adaptation of Shewanella putrefaciens for swimming in planktonic and structured environments
Edelmann, D. B.; Jakob, A. M.; Wilson, L. G.; Colin, R.; Brandt, D.; Eck, F.; Kalinowski, J.; Thormann, K. M.
10.1101/2024.10.15.618407 — microbiology — Posted on 2024-10-16
2820 DDX3 regulates the cap-independent translation of the Japanese encephalitis virus via its interactions with PABP1 and the untranslated regions of the viral genome
Li, C.; Zhang, L.; Tang, C.; Chen, X.; Shi, J.; Li, Q.; Jiao, X.; GUo, J.; Wang, B.; Bu, K.; Wahaab, A.; Yuan, Y.; Sun, M.-a.; Li, Y.
10.1101/2024.10.15.618401 — microbiology — Posted on 2024-10-16
2821 Pathogenic mechanisms of Plasmodium falciparum egress unveiled by a microvascular 3D blood-brain barrier model
Piatti, L.; Batzilla, A.; Nakaki, F.; Fleckenstein, H.; Korbmacher, F.; Long, R. K. M.; Schraivogel, D.; Hawkins, J. A.; Romero-Urunuela, T.; Lopez-Gutierrez, B.; Sanz, S.; Schwab, Y.; Steinmetz, L. M.; Sharpe, J.; Bernabeu, M.
10.1101/2024.10.15.618439 — microbiology — Posted on 2024-10-16
2823 A novel PhoPQ-potentiated mechanism of colistin resistance impairs membrane integrity in Pseudomonas aeruginosa
Hsieh, Y.-Y. P.; O'Keefe, I. P.; Sun, W.; Wang, Z.; Yang, H.; Vu, L. M.; Ernst, R. K.; Dandekar, A. A.; Malik, H. S.
10.1101/2024.10.15.618514 — microbiology — Posted on 2024-10-16
2824 RNAi epimutations conferring antifungal drug resistance are inheritable
Perez-Arques, C.; Navarro-Mendoza, M. I.; Xu, Z.; Walther, G.; Heitman, J.
10.1101/2024.10.15.618540 — microbiology — Posted on 2024-10-16
2827 Aerotolerant methanogens use seaweed and seagrass metabolites to drive marine methane emissions
Hall, N.; Wong, W. W.; Lappan, R.; Ricci, F.; Glud, R. N.; Kawaichi, S.; Rotaru, A.-E.; Greening, C.; Cook, P.
10.1101/2024.10.14.618369 — microbiology — Posted on 2024-10-16
2829 HSV-1 Infection Alters MAPT Splicing and Promotes Tau Pathology in Neural Models of Alzheimer's Disease
Ijezie, E. C.; Miller, M. J.; Hardy, C.; Jarvis, A. R.; Czajka, T.; D'Brant, L.; Rugenstein, N.; Waickman, A.; Murphy, E.; Butler, D.
10.1101/2024.10.16.618683 — microbiology — Posted on 2024-10-16
2831 Longitudinal profiling of B cells primed by mRNA vaccine and recalled by Omicron variants uncovers antibodies broadly neutralizing sarbecoviruses
Chen, X.; Li, L.; Du, R.; Wang, Z.; Li, Y.; Sun, Y.; Qin, R.; Feng, H.; Hu, L.; Chen, X.; Lu, M.; Huang, X.; Jiang, L.; Zuo, T.
10.1101/2024.10.13.618110 — immunology — Posted on 2024-10-16
2832 The Autonomic Nervous System (ANS)-Immune Network in People Living With HIV
Mueller, B. R.; Mehta, M.; Campbell, M.; Neupane, N.; Cedillo, G.; Lee, G.; Coyle, K.; Qi, J.; Chen, Z.; George, M. C.; Robinson-Papp, J.
10.1101/2024.10.15.618447 — immunology — Posted on 2024-10-16
2834 Building neurovascular tissue from autologous blood for modeling brain-activity
Arora, R.; Bhardwaj, A.; Panda, N. K.; Sinharay, S.; Bakshi, J.; Virk, R. S.; Munjal, S.; Nagamani, B.; Nayak, G.; Patro, S. K.; Sharma, A.; Das, R.; Gupta, T.; Bhadada, S.; Pal, R.; Pal, A.; Mallik, N.; Premkumar, M.; Mohindra, R.; Dixit, R.; Pal, M.; Rashid, S.; Sharma, M.
10.1101/2024.10.16.617820 — neuroscience — Posted on 2024-10-16
2838 Study of Plasma Adiponectin Levels in Patients with Metabolic Syndrome and Therapeutic Indication in Bangladesh
Parul, S. S.; Ahmmed, R.; Hasan, M. T.; Islam, A.; Rahman, M. M.; Manirujjaman, M.; Bari, M. W.; Ahmed, M. S.; Hasan, M. S.; Islam, M. A.
10.1101/2024.10.15.618480 — biochemistry — Posted on 2024-10-16
2840 Intranasal self-amplifying RNA SARS-CoV-2 vaccine produces protective respiratory and systemic immunity and prevents viral transmission
Jennewein, M. F.; Schultz, M. D.; Beaver, S.; Battisti, P.; Bakken, J.; Hanson, D.; Akther, J.; Zhou, F.; Mohamath, R.; Singh, J.; Cross, N.; Kasal, D. N.; Ykema, M.; Reed, S.; Kalange, D.; Cheatwood, I. R.; Tipper, J. L.; Foote, J. B.; King, R. G.; Harrod, K. S.; Silva-Sanchez, A.; Botta, D.; Gerhardt, A.; Casper, C.; Randall, T. D.; Lund, F. E.; Voigt, E. A.
10.1101/2022.11.10.515993 — immunology — Posted on 2024-10-16
2844 Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers.
Ray, N. J.; Cullell, N.; Clark, O. J.; Delgado-Sanchez, A.; Caruana, G.; Elias-Mas, A.; Ferrer, J.; Buongiorno, M.; Castejon, J.; Sanchez-Benavide, G.; Granell, E.; Correa-Muller, S.; Krupinski, J.
10.1101/2024.10.14.618324 — neuroscience — Posted on 2024-10-16
2845 Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language
Hong, Z.; Wang, H.; Zada, Z.; Gazula, H.; Turner, D.; Aubrey, B.; Niekerken, L.; Doyle, W.; Devore, S.; Dugan, P.; Friedman, D.; Devinsky, O.; Flinker, A.; Hasson, U.; Nastase, S.; Goldstein, A.
10.1101/2024.06.12.598513 — neuroscience — Posted on 2024-10-16
2846 Genome and tissue-specific transcriptome of the tropical milkweed (Asclepias curassavica)
Feng, H.; Zhang, J.; Powell, A. F.; Buttelman, G. L.; Yang, L.; Yan, E.; Wang, F.; Broyles, S. B.; Jander, G.; Strickler, S. R.
10.1101/2024.01.12.575411 — plant biology — Posted on 2024-10-16
2852 New insights into past and future invasion of Drosophila suzukii using novel genomic resources and statistical methods to combine individual and pool sequencing data
Camus, L.; Rode, N. O.; Serga, S.; Loiseau, A.; Chen, X.; Iampietro, C.; Kenis, M.; Marande, W.; Mensch, J.; Parrinello, H.; Savic Veselinovic, M.; Valiere, S.; Zhang, J.; Estoup, A.; Boitard, S.; Gautier, M.
10.1101/2024.10.11.617812 — evolutionary biology — Posted on 2024-10-16
2853 Integrative analysis of higher-order transcriptome organisation and RNA condensation principles
Klobucar, T.; Novljan, J.; Iosub, I. A.; Kokot, B.; Urbancic, I.; Jones, D. M.; Chakrabarti, A. M.; Luscombe, N.; Ule, J.; Modic, M.
10.1101/2024.10.14.618182 — molecular biology — Posted on 2024-10-16
2854 Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii
Hamami, E.; Huo, W.; Castaneda, A.; Bai, J.; Syal, S.; Ortiz-Marquez, J. C.; van Opijnen, T.; Geisinger, E.; Isberg, R. R.
10.1101/2023.10.03.560562 — microbiology — Posted on 2024-10-16
2855 Enhanced Hippocampal Spare Capacity in Q175DN Mice Despite Elevated mHTT Aggregation
Solem, M. A.; Pelzel, R.; Rozema, N. B.; Brown, T. G.; Reid, E.; Mansky, R. H.; Gomez-Pastor, R.
10.1101/2024.10.14.618355 — neuroscience — Posted on 2024-10-16
2856 Increased listening effort and cochlear neural degeneration underlie behavioral deficits in speech perception in noise in normal hearing middle-aged adults.
Zink, M. E.; Zhen, L.; McHaney, J. R.; Klara, J.; Yurasits, K.; Cancel, V.; Flemm, O.; Mitchell, C.; Datta, J.; Chandrasekaran, B.; Parthasarathy, A.
10.1101/2024.08.01.606213 — neuroscience — Posted on 2024-10-16
2858 Representations of the intrinsic value of information in mouse orbitofrontal cortex
Bussell, J. J.; Badman, R. P.; Marton, C. D.; Bromberg-Martin, E. S.; Abbott, L.; Rajan, K.; Axel, R.
10.1101/2023.10.13.562291 — neuroscience — Posted on 2024-10-16
2861 AgeML: Age modelling with Machine Learning
Garcia Condado, J.; Tellaetxe, I.; Cortes, J.; Erramuzpe, A.
10.1101/2024.05.02.592130 — bioinformatics — Posted on 2024-10-16
2864 Genetically encoded fluorescent sensors for visualizing polyamine levels, uptake, and distribution
Tamura, R.; Chen, J.; De Jaeger, M.; Morris, J. F.; Scott, D. A.; Vangheluwe, P.; Looger, L. L.
10.1101/2024.08.21.609037 — cell biology — Posted on 2024-10-16
2865 Emergence of Dip2-mediated Specific DAG-based PKC Signalling Axis in Eukaryotes
Shambhavi, S.; Mondal, S.; Chakraborty, A.; Shukla, N.; Panda, B. K.; Kumar, S.; Kinatukara, P.; Pal, B.; Kamat, S. S.; Sankaranarayanan, R.
10.1101/2024.10.15.618531 — cell biology — Posted on 2024-10-16
2866 The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2
Longhurst, A. D.; Wang, K.; Suresh, H. G.; Ketavarapu, M.; Ward, H. N.; Jones, I. R.; Narayan, V.; Hundley, F. V.; Hassan, A. Z.; Boone, C.; Myers, C.; Shen, Y.; Ramani, V.; Andrews, B. J.; Toczyski, D. P.
10.1101/2024.03.18.585604 — molecular biology — Posted on 2024-10-16
2867 PEPITEM Tripeptides and Peptidomimetics: Next-Generation Modulators of Inflammation in Immune-Mediated Conditions
Saviano, A.; Apta, B.; Tull, S.; Pezhman, L.; Fatima, A.; Sevim, M.; Mete, A.; Chimen, M.; Schettino, A.; Marigliano, N.; McGettrick, H. M.; Iqbal, A. J.; Maione, F.; Rainger, G. E.
10.1101/2024.10.14.618151 — immunology — Posted on 2024-10-16
2871 Predicting the effect of CRISPR-Cas9-based epigenome editing
Batra, S. S.; Cabrera, A.; Spence, J. P.; Goell, J.; Anand, S. S.; Hilton, I.; Song, Y. S.
10.1101/2023.10.03.560674 — bioinformatics — Posted on 2024-10-16
2873 Zymoseptoria tritici proteins structurally related to UmV-KP4 and UmV-KP6 are toxic to fungi, and define novel structural families of fungal effectors
de Guillen, K.; Mammri, L.; Gracy, J.; Padilla, A.; BARTHE, P.; Hoh, F.; Lahfa, M.; Rouffet, J.; Petit-Houdenot, Y.; Kroj, T.; Lebrun, M.-H.
10.1101/2024.10.14.618152 — biochemistry — Posted on 2024-10-16
2875 Pan-cistrome analysis of the leaf accessible chromatin regions of 214 maize inbred lines
Zhu, Y.; Ngan, H.; Zhu, T.; Nan, L.; Li, W.; Xiao, Y.; Zhuo, L.; Chen, D.; Tu, X.; Gao, K.; Yan, J.; Zhong, S.; Yang, N.
10.1101/2024.10.14.618191 — genomics — Posted on 2024-10-16
2878 A novel downstream factor in willows replaces the ancestral sex determining gene
Wang, Y.; Xue, Z.; Zhang, R.-G.; Horandl, E.; Wang, X.-R.; Mank, J. E.; He, L.
10.1101/2024.10.14.618180 — evolutionary biology — Posted on 2024-10-16
2880 The future abundance of key bird species for pathogen transmission in the Netherlands
Dellar, M.; Sierdsema, H.; van Bodegom, P. M.; Schrama, M. J.; Geerling, G.
10.1101/2024.10.14.617534 — ecology — Posted on 2024-10-16
2881 GLE1 dysfunction compromises cellular homeostasis, spatial organization, and peripheral axon branching
Zarybnicky, T.; Lindfors, S.; Metso, S.; Szabo, Z.; Valtonen, R.; Tulppo, M.; Magga, J.; Saarimaki, S.; Blauer, S.; Miinalainen, I.; Kerkela, R.; Vaananen, J.; Kivela, R.; Zhang, F.-P.; Sipila, P.; Hinttala, R.; Kuure, S.
10.1101/2024.10.14.618161 — developmental biology — Posted on 2024-10-16
2883 Behavioral and neural alterations of the ventral tegmental area by Cafeteria diet exposure in rats
Lalanza, J. F.; Oyem, J. C.; Huijgens, P. T.; McCutcheon, J. E.; Heijkoop, R.; Snoeren, E. M. S.
10.1101/2024.10.14.618156 — neuroscience — Posted on 2024-10-16
2884 Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity
Bisht, A.; Pippadpally, S.; Majumder, S.; Gopi, A. T.; Das, A.; Sahi, C.; Ramaswami, M.; Kumar, V.
10.1101/2024.10.14.618171 — neuroscience — Posted on 2024-10-16
2885 Human Brain-Wide Activation of Sleep Rhythms
Wang, H.; Zou, Q.; Zhang, J.; Gao, J.-H.; Liu, Y.
10.1101/2024.10.14.618165 — neuroscience — Posted on 2024-10-16
2887 Systems-level analysis provides insights on methanol-based production of L-glutamate and its decarboxylation product γ-aminobutyric acid by Bacillus methanolicus
Irla, M.; Naerdal, I.; Virant, D.; Brautaset, T.; Busche, T.; Goranovic, D.; Haupka, C.; Heux, S.; Kosec, G.; Rückert-Reed, C.; Wendisch, V. F.; Fernandes Brito, L.; Vicente, C. M.
10.1101/2024.10.14.618164 — systems biology — Posted on 2024-10-16
2889 Data- and knowledge-derived functional landscape of human solute carriers
Goldmann, U.; Wiedmer, T.; Garofoli, A.; Sedlyarov, V.; Bichler, M.; Wolf, G.; Christodoulaki, E.; Ingles-Prieto, A.; Ferrada, E.; Frommelt, F.; Teoh, S. T.; Leippe, P.; Haladik, B.; Onea, G.; Pfeifer, M.; Kohlbrenner, M.; Chang, L.; Selzer, P.; Reinhardt, J.; Digles, D.; Ecker, G. F.; Osthushenrich, T.; MacNamara, A.; Malarstig, A.; Hepworth, D.; Superti-Furga, G.
10.1101/2024.10.14.618155 — systems biology — Posted on 2024-10-16
2890 GCS-H2 is essential for growth as it acts as the main relay for mitochondrial lipoylation in heterotrophic tissues of Arabidopsis thaliana
Przybyla-Toscano, j.; Boussardon, C.; Juvany, M.; Alseekh, S.; Modde, K.; Valentin, A.; Stenlund, h.; Bauwe, H.; Fernie, A. R.; Keech, O.
10.1101/2024.10.14.617781 — plant biology — Posted on 2024-10-16
2892 PPARalpha-ERRalpha crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression
Antwi, M. B.; Lefere, S.; Clarisse, D.; Koorneef, L.; Heldens, A.; Onghena, L.; Decroix, K.; Fijalkowska, D.; Thommis, J.; Hellemans, M.; Hoorens, A.; Geerts, A.; Devisscher, L.; De Bosscher, K.
10.1101/2024.10.14.618024 — pharmacology and toxicology — Posted on 2024-10-16
2893 Chronic obesity does not alter cancer survival in Tp53R270H/+ mice
Panzeri, I.; Madaj, Z.; Fagnocchi, L.; Apostle, S.; Tompkins, M.; Hostetter, G.; Pospisilik, J. A.
10.1101/2024.10.14.618190 — cancer biology — Posted on 2024-10-16
2894 Nonlinear Singular Value Decomposition Beamforming for Ultrasound Imaging of Gas Vesicles
Zhang, G.; Vert, M.; Nouhoum, M.; Rivera, E.; Haidour, N.; Jimenez, A.; Deffieux, T.; Barral, S.; Hersen, P.; Rabut, C.; Shapiro, M.; Tanter, M.
10.1101/2024.10.14.618186 — biophysics — Posted on 2024-10-16
2896 Searching for Sulfotyrosines (sY) in a HA(pY)STACK
Tzvetkov, J.; Eyers, C. E.; Eyers, P. A.; Ramsbottom, K. A.; Sun, Z.; Deutsch, E. W.; Jones, A. R.
10.1101/2024.10.14.618131 — bioinformatics — Posted on 2024-10-16
2898 Stress-free Bioprinting of Human Primary and iPSC-derived Islets with Retained Functionality
Poklar, M.; K, R.; Wiegand, C.; Mizerak, B.; Wang, R.; Florentino, R. M.; Liu, Z.; Soto-Gutierrez, A.; Kumta, P. N.; Banerjee, I.
10.1101/2024.10.14.617656 — bioengineering — Posted on 2024-10-16
2899 Charting the molecular landscape of neuronal organisation within the hippocampus using cryo electron tomography
Glynn, C.; Smith, J. L. R.; Case, M.; Csöndör, R.; Katsini, A.; Sanita, M. E.; Glen, T. S.; Pennington, A.; Grange, M.
10.1101/2024.10.14.617844 — biochemistry — Posted on 2024-10-16
2901 Better and faster collective decisions by larger fish shoals in the wild
Pacher, K.; Bierbach, D.; Sevinchan, Y.; Volmoeller, C.; Juarez-Lopez, A.; Jimenez-Jimenez, J. E.; Krause, S.; Wolf, M.; Romanczuk, P.; Arias-Rodriguez, L.; Krause, J.
10.1101/2024.10.14.618136 — animal behavior and cognition — Posted on 2024-10-16
2905 Effects of a transmissible cancer on life-history traits in Tasmanian devils
Strickland, K.; Jones, M. E.; Lachish, S.; Comte, S.; Hamede, R.; Hohenlohe, P. A.; McCallum, H.; Storfer, A.; Kruuk, L.
10.1101/2024.10.14.618139 — evolutionary biology — Posted on 2024-10-16
2908 PAF1C allosterically activates CDK12/13 kinase during RNAPII transcript elongation
Lopez Martinez, D.; Todorovski, I.; Noe Gonzalez, M.; Rusimbi, C.; Blears, D.; Khallou, N.; Han, Z.; Dirac-Svejstrup, A. B.; Svejstrup, J. Q.
10.1101/2024.10.14.618141 — molecular biology — Posted on 2024-10-16
2909 Genomic characterization of a unique population of Leishmania tropica in a new emerging focus of cutaneous leishmaniasis in Somali region of Ethiopia
Abera, A.; Monsieurs, P.; Pareyn, M.; Beyene, D.; Tasew, G.; Aroni-Soto, A.; Belachew, M.; Geleta, D.; Adnew, B.; Gidey, B.; Tadesse, H.; G/Egziabhier, A.; Abubeker, R.; Ali, A.; Tafess, K.; Rinke de Wit, T.; van Griensven, J.; Dujardin, J.-C.; Wolday, D.; Domagalska, M. A.
10.1101/2024.10.15.617758 — microbiology — Posted on 2024-10-16
2910 Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in Vivo
Pizzuto, M.; Monteleone, M.; Burgener, S. S.; Began, J.; Kurera, M.; Chia, J. R.; Frampton, E.; Crawford, J.; Oliveira, M.; Kenney, K. M.; Coombs, J. R.; Yamamoto, M.; Man, S. M.; Broz, P.; Pelegrin, P.; Schroder, K.
10.1101/2024.10.14.618051 — immunology — Posted on 2024-10-16
2913 Telomere length and cognitive function among middle-aged and older participants from communities underrepresented in aging research: A preliminary study
McLester-Davis, L. W. Y.; Norton, D.; Papale, L. A.; James, T. T.; Salazar, H.; Asthana, S.; Johnson, S. C.; Gooding, D. C.; Roy, T. R.; Alisch, R. S.; Hogan, K. J.; Drury, S. S.; Gleason, C. E.; Zuelsdorff, M.
10.1101/2024.10.14.618331 — neuroscience — Posted on 2024-10-16
2914 Treadmill step training promotes corticospinal tract plasticity after incomplete spinal cord injury
Eisdorfer, J. T.; Nacht, H. D.; Kowalski, T.; Thackray, J. T.; Martinez, A. M.; Zymoro, L.; Phu, M. V.; Hirpara, R. R.; Danish, B. S.; Wang, R.; Khondker, A.; Eisdorfer, A. B.; Tischfield, M.; Abraira, V. E. G.
10.1101/2024.10.14.618099 — neuroscience — Posted on 2024-10-16
2915 Network mechanisms in rapid-onset dystonia-parkinsonism
Moeller, M.; Nieweler, J. A.; Nikulin, V.; van Riesen, C.
10.1101/2024.10.14.618133 — neuroscience — Posted on 2024-10-16
2916 Paroxysmal Slow Wave Events as a diagnostic and predictive biomarker for post-traumatic epilepsy
Van Hameren, G.; Moradi, P.; Imtiaz, H.; Parker, E.; Mansoor, S.; Al Hadeed, L.; Albitar, M.; Alhosainy, Z.; Friedman, A.
10.1101/2024.10.14.618064 — neuroscience — Posted on 2024-10-16
2917 Deficient Memory, Long-Term Potentiation and Hippocampal Synaptic Plasticity in Galectin-4-KO Mice.
Brocca, M. E.; Mora-Rubio, A.; Alonso-Calvino, E.; Fernandez-Lopez, E.; Diez-Revuelta, N.; Guirado-Calatrava, J. C.; Alvarez-Velez, R.; Dopazo, A.; Lopez-Merino, E.; Martos-Punal, D.; Esteban, J. A.; Aguilar, J.; Higuero, A. M.; Abad-Rodriguez, J.
10.1101/2024.10.14.617868 — neuroscience — Posted on 2024-10-16
2919 THE FIRST COMPREHENSIVE FORENSIC GENETIC STUDY OF A MEMBER OF CHRISTOPHER COLUMBUS' FAMILY: HIS GREAT-GREAT-GRANDSON
Navarro Vera, I.; Yravedra Saez de los Terreros, J.; Bonilla, A.; Tirapu, M.; Albert, M.; Jimenez, P.; Herranz, D.; Garcia, C.
10.1101/2024.10.12.618003 — genomics — Posted on 2024-10-16
2920 A punctuated burst of massive genomic rearrangements and the origin of non-marine annelids
Vargas-Chavez, C.; Benitez-Alvarez, L.; Martinez-Redondo, G. I.; Alvarez-Gonzalez, L.; Salces-Ortiz, J.; Eleftheriadi, K.; Escudero, N.; Guiglielmoni, N.; Flot, J.-F.; Novo, M.; Ruiz-Herrera, A.; McLysaght, A.; Fernandez, R.
10.1101/2024.05.16.594344 — evolutionary biology — Posted on 2024-10-16
2921 BIMSA: Accelerating Long Sequence Alignment Using Processing-In-Memory
Alonso-Marin, A.; Fernandez, I.; Aguado-Puig, Q.; Gomez-Luna, J.; Marco-Sola, S.; Mutlu, O.; Moreto, M.
10.1101/2024.05.10.593513 — bioinformatics — Posted on 2024-10-16
2922 Data-driven evaluation of suitable immunogens for improved antibody selection
Waury, K.; Kvartsberg, H.; Zetterberg, H.; Blennow, K.; Teunissen, C. E.; Abeln, S.
10.1101/2024.10.07.617016 — bioinformatics — Posted on 2024-10-16
2923 Functional clustering of splice-altering variants in whole genome sequencing data reveals hidden heritability in rare variant disorder
Wang, Y.; van Dijk, C.; Timpanaro, I.; Hop, P. J.; Kenna, B.; Kooyman, M.; Aronica, E.; Pasterkamp, R. J.; van den Berg, L.; Cooper-Knock, J.; Project MinE ALS sequencing consortium, ; NYGC ALS consortium, ; Veldink, J.; Kenna, K.
10.1101/2023.05.30.542855 — bioinformatics — Posted on 2024-10-16
2924 Large protein databases reveal structural complementarity and functional locality
Szczerbiak, P.; Szydlowski, L. M.; Wydmanski, W.; Renfrew, P. D.; Koehler Leman, J.; Kosciolek, T.
10.1101/2024.08.14.607935 — bioinformatics — Posted on 2024-10-16
2929 Genetic diversity affects ecosystem functions across trophic levels as much as species diversity, but in an opposite direction
Fargeot, L.; Poesy, C.; Lefort, M.; Prunier, J. G.; Krick, M.; Verdonck, R.; Veyssiere, C.; Richard, M.; Legrand, D.; Loot, G.; Blanchet, S.
10.1101/2024.03.27.586944 — ecology — Posted on 2024-10-16
2930 Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway
Riedelbauch, S.; Masser, S.; Fasching, S.; Lin, S.-Y.; Salgania, H. K.; Aarup, M.; Ebert, A.; Jeske, M.; Levine, M. T.; Stelzl, U.; Andersen, P.
10.1101/2024.10.05.616775 — molecular biology — Posted on 2024-10-16
2932 Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A
Donaldson, G. P.; Reis, G. L.; Saad, M.; Wichmann, C.; Mamede, I.; Chen, G.; DelGaudio, N. L.; Zhang, D.; Aydin, B.; Harrer, C. E.; Castro, T. B. R.; Grivennikov, S.; Reis, B. S.; Stadtmueller, B. M.; Victora, G. D.; Mucida, D.
10.1101/2023.10.06.561290 — immunology — Posted on 2024-10-16
2933 Region-specific spreading depolarization drives aberrant post-ictal behavior
Mitlasoczki, B.; Gomez, A. G.; Kamali, M.; Babushkina, N.; Baues, M.; Kück, L.; Haubrich, A. N.; Tamiolakis, T.; Breuer, A.; Granak, S.; Schwering-Sohnrey, M.; Gerhauser, I.; Baumgärtner, W.; Ewell, L.; Opitz, T.; Pitsch, J.; Musall, S.; Surges, R.; Mormann, F.; Beck, H.; Wenzel, M.
10.1101/2024.10.12.618012 — neuroscience — Posted on 2024-10-16
2937 Structure-optimized sgRNA selection with PlatinumCRISPr for efficient Cas9 generation of knock-outs
Haussmann, I. U.; Dix, T. C.; McQuarrie, D. W.; Dezi, V.; Hans, A. I.; Arnold, R.; Soller, M.
10.1101/2022.12.15.520550 — molecular biology — Posted on 2024-10-16
2938 tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.
Bruch, A.; Lazarova, V.; Berg, M.; Krueger, T.; Schaeuble, S.; Kelani, A. A.; Mertens, B.; Lehenberger, P.; Kniemeyer, O.; Kaiser, S.; Panagiotou, G.; Gsaller, F.; Blango, M. G.
10.1101/2024.02.19.578369 — microbiology — Posted on 2024-10-16
2939 A Cortical Site that Encodes Vocal Expression and Reception
Pomberger, T.; Kaplan, K. S.; Carter, R.; Harmon, T. C.; Mooney, R.
10.1101/2024.10.15.618282 — neuroscience — Posted on 2024-10-16
2940 Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury
Zhao, Q.; Zhu, Y.; Ren, Y.; Zhao, L.; Zhao, J.; Yin, S.; Ni, H.; Zhu, R.; Cheng, L.; Xie, N.
10.1101/2024.01.23.576887 — neuroscience — Posted on 2024-10-16
2943 Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers.
Ray, N. J.; Cullell, N.; Clark, O. J.; Delgado-Sanchez, A.; Caruana, G.; Elias-Mas, A.; Ferrer, J.; Buongiorno, M.; Castejon, J.; Sanchez-Benavide, G.; Granell, E.; Correa-Muller, S.; Krupinski, J.
10.1101/2024.10.14.618324 — neuroscience — Posted on 2024-10-16
2944 Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical morphogenesis
Elorriaga, V.; Bouloudi, B.; Saillour, Y.; Morel, J.; Delberghe, E.; Azzam, P.; Moreau, M. X.; Stottmann, R.; Bahi-Buisson, N.; Pierani, A.; Spassky, N.; Causeret, F.
10.1101/2024.10.15.618167 — neuroscience — Posted on 2024-10-16
2945 Synchrony dynamics underlie irregular neocortical spiking
Pattadkal, J. J.; O'Shea, R. T.; Hansel, D.; Taillefumier, T.; Brager, D.; Priebe, N.
10.1101/2024.10.15.618398 — neuroscience — Posted on 2024-10-16
2947 Generalizability of Normative Models of Brain Morphometry Across Distinct Ethnoracial Groups
Ge, R.; Yu, Y.; New, F.; Haas, S. S.; Sanford, N.; Yu, K.; Leon, J. C. B.; Yang, G.; Gao, J.-H.; Nemoto, K.; Fukunaga, M.; Matsumoto, J.; Hashimoto, R.; Jahanshad, N.; Thompson, P. M.; Frangou, S.
10.1101/2024.10.14.618114 — bioinformatics — Posted on 2024-10-16
2948 Whistle variability and social acoustic interactions in bottlenose dolphins
Mustun, F.; Semenzin, C.; Rance, D.; Marachlian, E.; Guillerm, Z.-L.; Mancini, A.; Bouaziz, i.; Fleck, E.; Shashar, N.; de Polavieja, G. G.; Sumbre, G.
10.1101/2024.10.15.618471 — animal behavior and cognition — Posted on 2024-10-16
2950 Diversity of ancestral brainstem noradrenergic neurons across species and multiple biological factors
Kelberman, M. A.; Rodberg, E.; Arabzadeh, E.; Bair-Marshall, C. J.; Berridge, C. W.; Berrocoso, E.; Breton-Provencher, V.; Chandler, D. J.; Che, A.; Davy, O.; Devilbiss, D. M.; Downs, A. M.; Drummond, G.; Dvorkin, R.; Fazlali, Z.; Froemke, R. C.; Glennon, E.; Gold, J. I.; Ito, H.; Jiang, X.; Johansen, J. P.; Kaye, A. P.; Kim, J. R.; Kuo, C.-c.; Liu, R.-j.; Liu, Y.; Llorca-Torralba, M.; McCall, J. G.; McElligott, Z. A.; McKinney, A. M.; Miguelez, C.; Min, M.-Y.; Nowlan, A. C.; Omrani, M.; Pickering, A. E.; Poe, G. R.; Ranjbar-Slamloo, Y.; Razquin, J.; Rodenkirch, C.; Sales, A. C.; Satyasambit,
10.1101/2024.10.14.618224 — neuroscience — Posted on 2024-10-16
2951 Synaptic targets and cellular sources of CB1 cannabinoid receptor and vesicular glutamate transporter-3 expressing nerve terminals in relation to GABAergic neurons in the human cerebral cortex
Somogyi, P.; Horie, S.; Lukacs, I.; Hunter, E.; Sarkany, B.; Viney, T. J.; Livermore, J.; Plaha, P.; Stacey, R.; Ansorge, O.; El Mestikawy, S.; Zhao, Q.
10.1101/2024.10.14.618168 — neuroscience — Posted on 2024-10-16
2953 Optical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites
Sicard, A.; Tian, M.; Mostefai, Z.; Shi, S.; Cardoso, C.; Zamith, J.; Charrier, C.; Paoletti, P.; Mony, L.
10.1101/2024.10.14.618157 — neuroscience — Posted on 2024-10-16
2955 Diversification of Dentate Gyrus Granule Cell Subtypes is Regulated by Neuregulin1 Nuclear Back Signaling.
Rajebhosale, P.; Jiang, L.; Ressa, H. J.; Johnson, K. R.; Desai, N. S.; Jone, A.; Role, L. W.; Talmage, D. A.
10.1101/2024.10.15.618334 — neuroscience — Posted on 2024-10-16
2957 Cell-extrinsic controls over neocortical neuron fate and diversity
Baumann, N.; Morassut, I.; Puiggros, S. R.; Klingler, E.; Bartolini, G.; Fievre, S.; Jabaudon, D.
10.1101/2024.10.15.618395 — neuroscience — Posted on 2024-10-16
2959 ZMYND11 Functions in Bimodal Regulation of Latent Genes and Brain-like Splicing to Safeguard Corticogenesis
Chang, X.; Li, W.; Satoshi, M.; Huynh, C.; Cederquist, G.; Studer, L.; Iwafuchi, M.; Shillington, A.; Chronis, C.; Tchieu, J.
10.1101/2024.10.15.618524 — neuroscience — Posted on 2024-10-16
2960 Attention networks engage the default mode network related to policy precision under uncertainty
Yoon, D.; Kim, J.; Kim, D. H.; Shin, D. W.; Bong, S. H.; Kim, J.; Park, H.-j.; Jeong, B.
10.1101/2024.10.15.618415 — neuroscience — Posted on 2024-10-16
2961 From movements to words: action monitoring in the medial frontal cortex along a caudal to rostral prediction error gradient
Dorokhova, L.; Shen, S.; Peirolo, M.; Anton, J.-L.; Nazarian, B.; Sein, J.; Chanoine, V.; BELIN, P.; Loh, K. K.; Runnqvist, E.
10.1101/2024.10.14.618134 — neuroscience — Posted on 2024-10-16
2966 CRISPR-GPT: An LLM Agent for Automated Design of Gene-Editing Experiments
Qu, Y.; Huang, K.; Cousins, H.; Johnson, W. A.; Yin, D.; Shah, M. M.; Zhou, D.; Altman, R. B.; Wang, M.; Cong, L.
10.1101/2024.04.25.591003 — bioinformatics — Posted on 2024-10-15
2967 Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis
Huang, Y.-T.; Abdrabo, K. A. E.-S.; Phang, G. J.; Fan, Y.-H.; Wu, Y.-T.; Ou, J.-H.; Hulcr, J.
10.1101/2024.10.09.617500 — evolutionary biology — Posted on 2024-10-15
2968 Chai-1: Decoding the molecular interactions of life
Chai Discovery, ; Boitreaud, J.; Dent, J.; McPartlon, M.; Meier, J.; Reis, V.; Rogozhnikov, A.; Wu, K.
10.1101/2024.10.10.615955 — synthetic biology — Posted on 2024-10-15
2972 Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration
Lee, L. R.; Guillotin, B.; Rahni, R.; Hutchison, C.; Desvoyes, B.; Gutierrez, C.; Birnbaum, K. D.
10.1101/2023.11.28.569014 — plant biology — Posted on 2024-10-15
2974 Extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair towards development of somatic benchmarks
McDaniel, J. H.; Patel, V.; Olson, N. D.; He, H.-J.; He, Z.; Cole, K. D.; Schmitt, A.; Sikkink, K.; Sedlazeck, F.; Doddapaneni, H.; Jhangiani, S. N.; Muzny, D. M.; Gingras, M.-C.; Mehta, H.; Paulin, L. F.; Hastie, A. R.; Yu, H.-C.; Weigman, V.; Rojas, A.; Kennedy, K.; Remington, J.; Gonzalez, I.; Sudkamp, M.; Wiseman, K.; Lajoie, B. R.; Levy, S.; Jain, M.; Akeson, S.; Narzisi, G.; Steinsnyder, Z.; Reeves, C.; Shelton, J.; Kingan, S. B.; Lambert, C.; Bayabyan, P.; Wenger, A. M.; McLaughlin, I. J.; Adamson, A.; Kingsley, C.; Wescott, M.; Kim, Y.; Paten, B.; Park, J.; Violich, I.; Miga, K. H.; Ga
10.1101/2024.09.18.613544 — genomics — Posted on 2024-10-15
2976 Template switching during DNA replication is a prevalent source of adaptive gene amplification
Chuong, J.; Ben Nun, N.; Suresh, I.; Matthews, J.; De, T.; Avecilla, G.; Abdul-Rahman, F.; Brandt, N.; Ram, Y.; Gresham, D.
10.1101/2024.05.03.589936 — evolutionary biology — Posted on 2024-10-15
2979 Discovery of a multipotent cell type from the term human placenta
Vadakke-Madathil, S.; Bouhamida, E.; Wang, B.; Mathiyalagan, P.; Oniskey, M.; Santos-Gallego, C.; Hadley, M.; Croft, L.; Dekio, F.; Brody, R.; Gelber, S.; Sperling, R.; Chaudhry, H. W.
10.1101/2023.08.02.551028 — cell biology — Posted on 2024-10-15
2981 Nucleolar dynamics are determined by the ordered assembly of the ribosome
Sheu-Gruttadauria, J.; Yan, X.; Stuurman, N.; Vale, R. D.; Floor, S. N.
10.1101/2023.09.26.559432 — molecular biology — Posted on 2024-10-15
2983 Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy
Bridge, J.; Johnson, M. J.; Kim, J.; Wenthe, S.; Krueger, J.; Wick, B.; Kluesner, M.; Crane, A. T.; Bell, J.; Skeate, J. G.; Moriarity, B. S.; Webber, B. R.
10.1101/2024.09.03.611042 — immunology — Posted on 2024-10-15
2984 Integration of distinct cortical inputs to primary and higher order inhibitory cells of the thalamus
Puzzo, C. D.; Martinez-Garcia, R. I.; Liu, H.; Dyson, L. F.; Gilbert, W. O.; Cruikshank, S. J.
10.1101/2024.10.12.618039 — neuroscience — Posted on 2024-10-15
2985 Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language
Hong, Z.; Wang, K.; Zada, Z.; Gazula, H.; Turner, D.; Aubrey, B.; Niekerken, L.; Doyle, W.; Devore, S.; Dugan, P.; Friedman, D.; Devinsky, O.; Flinker, A.; Hasson, U.; Nastase, S.; Goldstein, A.
10.1101/2024.06.12.598513 — neuroscience — Posted on 2024-10-15
2986 Integrative genomics approach identifies glial transcriptomic dysregulation and risk in the cortex of individuals with Alcohol Use Disorder
Warden, A. S.; Salem, N. A.; Brenner, E.; Sutherland, G. T.; Stevens, J.; Kapoor, M.; Goate, A. M.; Mayfield, R. D.
10.1101/2024.08.16.607185 — neuroscience — Posted on 2024-10-15
2987 Expansion of a bacterial operon during cancer treatment ameliorates drug toxicity
Trepka, K.; Kidder, W. A.; Kyaw, T. S.; Halsey, T.; Olson, C. A.; Ortega, E. F.; Noecker, C.; Upadhyay, V.; Stanfield, D.; Steiding, P.; Guthrie, B. G.; Spanogiannopoulos, P.; Dumlao, D.; Turnbaugh, J. A.; Stachler, M. D.; Van Blarigan, E. L.; Venook, A. P.; Atreya, C. E.; Turnbaugh, P. J.
10.1101/2024.06.04.597471 — systems biology — Posted on 2024-10-15
2990 Learning enhances behaviorally relevant representations in apical dendrites
Benezra, S. E.; Patel, K. B.; Perez Campos, C.; Hillman, E. M. C.; Bruno, R. M.
10.1101/2021.11.10.468144 — neuroscience — Posted on 2024-10-15
2991 Human brain changes after first psilocybin use
Lyons, T.; Spriggs, M.; Kerkela, L.; Rosas, F.; Roseman, L.; Mediano, P.; Timmermann, C.; Oestreich, L.; Pagni, B.; Zeifman, R.; Hampshire, A.; Trender, W.; Douglass, H.; Girn, M.; Godfrey, K.; Kettner, H.; Sharif, F.; Espasiano, L.; Gazzaley, A.; Wall, M.; Erritzoe, D.; Nutt, D.; Carhart-Harris, R.
10.1101/2024.10.11.617955 — neuroscience — Posted on 2024-10-15
2994 Attentive graph neural network models for the prediction of blood brain barrier permeability
Collins, J. W.; Ebrahimkhani, M.; Ramirez, D.; Abedi, M.; Philippe-Venec, L.; Cole, B. M.; Moore, B.; Nwankwo, J. O.
10.1101/2024.10.12.617907 — pharmacology and toxicology — Posted on 2024-10-15
2996 NeKo: a tool for automatic network construction from prior knowledge
Ruscone, M.; Tsirvouli, E.; Checcoli, A.; Turei, D.; Barillot, E.; Saez-Rodriguez, J.; Martignetti, L.; Flobak, A.; Calzone, L.
10.1101/2024.10.14.618311 — bioinformatics — Posted on 2024-10-15
2999 General purpose genotypes and evolution of higher plasticity in clonality underlie knotweed invasion
Wang, S.; Liao, Z.; Cao, P.; Schmid, M. W.; Zhang, L.; Bi, J.; Endriss, S. B.; Zhao, Y.-j.; Parepa, M.; Hu, W.; Akamine, H.; Wu, J.; Ju, R.-t.; Bossdorf, O.; Richards, C. L.; Li, B.
10.1101/2024.10.13.618084 — ecology — Posted on 2024-10-15
3001 Examining the molecular clock hypothesis for the contemporary evolution of the rabies virus
Durrant, R.; Cobbold, C.; Brunker, K.; Campbell, K.; Dushoff, J.; Ferguson, E.; Jaswant, G.; Lugelo, A.; Lushasi, K.; Sikana, L.; Hampson, K.
10.1101/2023.09.04.556169 — microbiology — Posted on 2024-10-15
3007 ERG1A K+ Channel Increases Intracellular Calcium Concentration through Modulation of Calsequestrin1 in C2C12 Myotubes
Hockerman, G. H.; Pratt, E.; Guha, S.; LaVigne, E.; Whitmore, C.; Khader, O.; McClure, N.; Zampieri, S.; Koran, J.; Wang, W.-H.; Pond, A. L.
10.1101/2023.12.04.569937 — physiology — Posted on 2024-10-15
3009 TGF-β induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis
Wang, Z.; Elbanna, Y.; Godet, I.; Peters, L.; Lampe, G.; Chen, Y.; Xavier, J.; Huse, M.; Massague, J.
10.1101/2024.10.15.618357 — cancer biology — Posted on 2024-10-15
3010 In vitro models to mimic tumor endothelial cell-mediated immune cell reprogramming in lung adenocarcinoma
Krejbich, M.; Fresquet, J.; Navarro, E.; Forest, V.; Cotinat, M.; Isen, V.; Perdrieau, H.; Chatelain, C.; Dochez, V.; Roulois, D.; Boisgerault, N.; Redon, R.; Corre, I.; Blanquart, C.; Treps, L.
10.1101/2024.10.13.618092 — cancer biology — Posted on 2024-10-15
3011 Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo
Berkamp, S.; Jungbluth, L.; Katranidis, A.; Mostafavi, S.; Korculanin, O.; Lu, P.-H.; Sharma, L.; Thukral, L.; Fitter, J.; Dunin-Borkowski, R. E.; Sachse, C.
10.1101/2024.10.15.618463 — biophysics — Posted on 2024-10-15
3013 Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease
D'Oliviera, A.; Dai, X.; Mottaghinia, S.; Olson, S.; Geissler, E. P.; Etienne, L.; Zhang, Y.; Mugridge, J. S.
10.1101/2023.02.20.529306 — biochemistry — Posted on 2024-10-15
3015 Differential expression and modulation of presenilin-1 and presenilin-2 in neural cell lines
Eccles, M. K.; Woodfield, A.; Milligan Armstrong, A.; Agostino, M.; Groth, D. M.; Verdile, G.
10.1101/2024.10.15.618376 — cell biology — Posted on 2024-10-15
3016 A fine kinetic balance of interactions directs transcription factor hubs to genes
Fallacaro, S.; Mukherjee, A.; Ratchasanmuang, P.; Zinski, J.; Haloush, Y. I.; Shankta, K.; Mir, M.
10.1101/2024.04.16.589811 — molecular biology — Posted on 2024-10-15
3017 nsGSLs on tumors impair anti-tumor immune responses by OT-I T cells in vitro and support tumor growth in vivo
Verkerk, T.; Selten, A. A. F.; Zandhuis, N. D.; Zhang, T.; Wuhrer, M.; Spaapen, R. M.; van Ham, S. M.
10.1101/2024.10.13.617339 — immunology — Posted on 2024-10-15
3018 Region-specific spreading depolarization drives aberrant post-ictal behavior
Mitlasozki, B.; Gomez, A. G.; Kamali, M.; Babushkina, N.; Baues, M.; Kück, L.; Haubrich, A. N.; Tamiolakis, T.; Breuer, A.; Granak, S.; Schwering-Sohnrey, M.; Gerhauser, I.; Baumgärtner, W.; Ewell, L.; Opitz, T.; Pitsch, J.; Musall, S.; Surges, R.; Mormann, F.; Beck, H.; Wenzel, M.
10.1101/2024.10.12.618012 — neuroscience — Posted on 2024-10-15
3021 Multi-behavioral phenotyping in zebrafish identifies a novel disruptor of non-associative learning with environmental and human relevance
Leuthold, D.; Herold, N. K.; Nerlich, J.; Bartmann, K.; Scharkin, I.; Hallermann, S. J.; Schweiger, N.; Fritsche, E.; Tal, T.
10.1101/2024.09.25.613874 — pharmacology and toxicology — Posted on 2024-10-15
3022 Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling.
Guzman, A.; Kawase, T.; Devanny, A. J.; Efe, G.; Navaridas, R.; Yu, K.; Regunath, K.; Mercer, I. G.; Avard, R. C.; Muniz de Queiroz, R.; Rustgi, A. K.; Kaufman, L. J.; Prives, C.
10.1101/2024.10.13.618100 — cancer biology — Posted on 2024-10-15
3024 3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain
Daly, S.; Bulovaite, E.; Handa, A.; Morris, K.; Muresan, L.; Adams, C.; Kaizuka, T.; Kitching, A.; Spark, A.; Chant, G.; O'Holleran, K.; Grant, S. G. N.; Horrocks, M. H.; Lee, S. F.
10.1101/2024.10.14.617231 — biophysics — Posted on 2024-10-15
3025 Model-free machine learning-based 3D single molecule localisation microscopy
Boland, M. d.; Flaxman, S.; Lightley, J. P. E.; Garcia, E.; Kumar, S.; Dunsby, C.; Neil, M. A. A.; French, P. P. W.; Cohen, E. A. K.
10.1101/2024.10.14.618179 — biophysics — Posted on 2024-10-15
3026 Shaping the mechanical properties of a gelatin hydrogel interface via amination
Adorno, G. R.; Timmer, K. B.; Chang, R. S. H.; Shi, J.; Rogers, S.; Harley, B.
10.1101/2024.10.14.618299 — bioengineering — Posted on 2024-10-15
3027 The first near-complete genome assembly of pig: enabling more accurate genetic research
Cao, C.; Miao, J.; Xie, Q.; Sun, J.; Cheng, H.; Zhang, Z.; Wu, F.; Liu, S.; Ye, X.; Zhang, Z.; Wang, Q.; Pan, Y.; Wang, Z.
10.1101/2024.10.13.617951 — genomics — Posted on 2024-10-15
3031 Direct and indirect selection in a proofreading polymerase
Husain, K.; Sachdeva, V.; Ravasio, R.; Peruzzo, M.; Liu, W.; Good, B. H.; Murugan, A.
10.1101/2024.10.14.618309 — evolutionary biology — Posted on 2024-10-15
3033 Head-to-head comparison of nuclear imaging approaches to quantify tumor CD8+ T-cell infiltration
Sandker, G. G. W.; Raave, R.; Antunes, I. F.; Boswinkel, M.; Cornelissen, L.; Franssen, G. M.; Molkenboer-Kuenen, J.; Wierstra, P. J.; Hagemans, I. M.; de Vries, E. F. J.; Bussink, J.; Adema, G.; Verdoes, M.; Aarntzen, E. H. J. G.; Heskamp, S.
10.1101/2024.10.13.618082 — immunology — Posted on 2024-10-15
3034 Single-Cell Antigen Receptor Sequencing in Pigs with Influenza
Gu, W.; Madrid, D. M. d. C.; Clements, S.; Touchard, L.; Bivens, N.; Zane, G.; Zhou, M.; Lee, K.; Driver, J. P.
10.1101/2024.10.13.617920 — immunology — Posted on 2024-10-15
3035 Extensive monolayer formation depends on a subpopulation of transplanted human iPSC-derived RPE cells
Tessmer, K.; Gasparini, S. J.; Schmidtke, K.; Adhikari, T.; Michalke, L.; Hammer, J.; Loureiro, L.; Last, A.; Chelius, N.; Kurtz, A.; Johannsen, H.; Carido, M.; Ferguson, S.; Petzold, A.; Friedrich, U. A.; Kurth, T.; Dahl, A.; Feldmann, A.; Almedawar, S.; Knoebel, S.; Ader, M.
10.1101/2024.10.15.618147 — neuroscience — Posted on 2024-10-15
3036 Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC-derived neurons
Kadam, V.; Wacker, M.; Oeckl, P.; Korneck, M.; Dannenmann, B.; Skokowa, J.; Hauser, S.; Otto, M.; Synofzik, M.; Mengel, D.
10.1101/2024.10.14.618132 — neuroscience — Posted on 2024-10-15
3037 Light-guided actin polymerization drives directed motility in protocells
Matsubayashi, H. T.; Razavi, S.; Rock, T. W.; Nakajima, D.; Nakamura, H.; Kramer, D. A.; Matsuura, T.; Chen, B.; Murata, S.; Nomura, S.-i. M.; Inoue, T.
10.1101/2024.10.14.617543 — synthetic biology — Posted on 2024-10-15
3038 Retinoid X Receptor Signaling Mediates Cancer Cell Lipid Metabolism in the Leptomeninges
Tong, X.; Remsik, J.; Brook, J.; Pentrova, B.; Li, M. J.; Snyder, J.; Sidharta, M.; Chabot, K.; Estrera, R.; Osei-Guyening, I.; Nobre, A. R. L. C.; Wang, H.; Osman, A.; Piedrafita-Ortiz, S.; Wong, A.; Manoranjan, B.; Zhou, T.; Murali, R.; Xu, L.; Koche, R.; He, Y.; Kanarek, N.; Boire, A.
10.1101/2024.10.13.618083 — cancer biology — Posted on 2024-10-15
3039 The long non-coding RNA FAM30A regulates the Musashi2-RUNX1 axis and is required for LSC function in AML cells
Calvo Sanchez, J.; Scott, M. T.; Varnava, A.; Alakhras, T.; Wedler, A.; Misiak, D.; Bley, N.; Ihling, C.; Sinz, A.; Keeshan, K.; Hüttelmaier, S.; Vetrie, D.; Köhn, M.
10.1101/2024.10.13.618058 — cancer biology — Posted on 2024-10-15
3041 Optimal network sizes for most robust Turing patterns
Ahmad Shaberi, H. S.; Kappassov, A.; Matas-Gil, A.; Endres, R. G.
10.1101/2024.10.15.618426 — biophysics — Posted on 2024-10-15
3045 Nanoparticles use magnetoelectricity to target and eradicate cancer cells
Bryant, J. M.; Stimphil, E.; Andre, V. L.; Shotbolt, M.; Zhang, E.; Estrella, V. C.; Husain, K.; Weygand, J.; Marchion, D.; Lopez, A. S.; Abrahams, D.; Chen, S.; Abdel-Mottaleb, M.; Conlan, S.; Oraiqat, I. M.; Khatri, V. M.; Guevara, J. A.; Pilon-Thomas, S. A.; Redler, G. H.; Latifi, K.; Raghunand, N.; Yamoah, K.; Hoffe, S. E.; Costello, J. R.; Frakes, J. M.; Liang, P.; Khizroev, S.; Gatenby, R. A.; Malafa, M.
10.1101/2024.10.13.618075 — bioengineering — Posted on 2024-10-15
3047 Mangiferin As A Potential Inhibitor Of Transthyretin Fibrillogenesis
Grudinina, N.; Petukhov, M. G.; Shaldzhyan, A. A.; Zabrodskaya, Y. A.; Gavrilova, N. V.; Morozkina, S. N.; Egorov, V. V.
10.1101/2024.10.09.617482 — molecular biology — Posted on 2024-10-15
3049 Characteristics of Vitelline Warbler songs and calls
Cummings, W.; Goodman, D. D. L.; Layne, C. D.; Singer, K. I.; Thomas, M. W.
10.1101/2024.10.12.617988 — evolutionary biology — Posted on 2024-10-15
3050 Wild Florida Mottled Ducks demonstrate strong heterogeneity in their humoral innate immune response
Ayala, A. J.; Cheng, M.; Hellinger, T. A.; McBride, K. M.; Webb, J.; Fanning, A.; Snyder, P.; Ferragamo, M.; Garcia, S. C.; Sterner, N.; Bischoff, K. L.; Moreno, S.-A.; Ogbunugafor, C. B.
10.1101/2024.10.12.617993 — ecology — Posted on 2024-10-15
3053 Pan-Prediction of MHC-II Restricted Epitopes Across Species via an Alphafold-based Quantification Scheme
Wang, S.; Kong, L.; Hu, D.; Zheng, L.; Fei, C.; Du, L.; Tang, Z.; Wang, S.; Xu, S.; Yang, H.; Zhang, N.
10.1101/2024.10.11.617946 — immunology — Posted on 2024-10-15
3054 Loop Grafting Improves Neuraminidase Protein Vaccine Production
Rijal, P.; Wei, L.; Paesen, G. C.; Stuart, D. I.; Howarth, M. R.; Huang, K.-Y. A.; Bowden, T. A.; Townsend, A. R.
10.1101/2024.10.11.617814 — immunology — Posted on 2024-10-15
3056 ABI5 Binding Proteins are substrates of key components in the ABA core signaling pathway
Finkelstein, R. R.; Lynch, T.; Erickson McNally, B. J.; Losic, T.; Lundquist, J.
10.1101/2024.10.11.617944 — plant biology — Posted on 2024-10-15
3057 A novel toolbox of GATEWAY-compatible vectors for rapid functional gene analysis in soybean composite plants
Mejias, J.; Margets, A.; Bredow, M.; Foster, J.; Khwanbua, E.; Goshon, J.; Maier, T. A.; Whitham, S. A.; Innes, R. W.; Baum, T. J.
10.1101/2024.10.12.617978 — plant biology — Posted on 2024-10-15
3059 Manipulation of the brown glume and internode 1 gene leads to alterations in lignified tissue coloration, lignification, and pathogen resistance in wheat
Hua, L.; Song, R.; Hao, X.; Zhang, J.; Liu, Y.; Luo, J.; Ren, X.; Li, H.; Wang, G.; Rehman, S. u.; Wu, J.; Fu, D.; Dong, Y.; Wang, X.; Zhang, C.; Chen, S.
10.1101/2024.10.11.617803 — plant biology — Posted on 2024-10-15
3060 Thermal biology of aphids and implications for agriculture and food security
Villena, O. C.; Arab, A.; Armbruster, P. A.; Markovich, E.; Zhang, K.; Tonnang, H. E.; Sokame, B. M.; Kreuze, J. F.; Carhuapoma, P. F.; Gamarra, H. A.; Johnson, L. R.
10.1101/2024.10.13.618050 — plant biology — Posted on 2024-10-15
3062 Attentive graph neural network models for the prediction of blood brain barrier permeability
Collins, J. W.; Ebrahimkhani, M.; Ramirez, D.; Abedi, M.; Philippe-Venec, L.; Cole, B. M.; Moore, B.; Nwankwo, J. O.
10.1101/2024.10.12.617907 — pharmacology and toxicology — Posted on 2024-10-15
3063 Proximal Tubule-on-Chip for Predicting Cation Transport: Dynamic Insights into Drug Transporter Expression and Function
Petit, I.; Faucher, Q.; Bernard, J.-S.; Giunchi, P.; Humeau, A.; Sauvage, F.-L.; Marquet, P.; Vedrenne, N.; Di Meo, F.
10.1101/2024.10.12.617976 — pharmacology and toxicology — Posted on 2024-10-15
3072 Comet fragment-ion indexing for enhanced peptide sequencing
McGann, C. D.; Bergstrom, E. J.; Sharma, V.; Heil, L. R.; Yu, Q.; Eng, J. K.; Schweppe, D. K.
10.1101/2024.10.11.617953 — bioinformatics — Posted on 2024-10-15
3077 Texture profile analysis and rheology of plant-based and animal meat
Dunne, R. A.; Darwin, E. C.; Perez Medina, V. E.; Levenston, M.; St. Pierre, S. R.; Kuhl, E.
10.1101/2024.10.11.617917 — bioengineering — Posted on 2024-10-15
3084 Pre-exposure to stress reduces loss of community and genetic diversity following severe environmental disturbance
Xu, C. C. Y.; Fugere, V.; Barbosa da Costa, N.; Beisner, B. E.; Bell, G. A.; Cristescu, M. E.; Fussmann, G. F.; Gonzalez, A.; Shapiro, B. J.; Barrett, R. D. H.
10.1101/2024.10.11.617827 — evolutionary biology — Posted on 2024-10-15
3089 The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization
Gramatica, A.; Miller, I. G.; Ward, A. R.; Khan, F.; Kemmer, T. J.; Weiler, J.; Huynh, T. T.; Zumbo, P.; Kurland, A. P.; Leyre, L.; Ren, Y.; Klevorn, T.; Copertino, D. C.; Chukwukere, U.; Levinger, C.; Dilling, T. R.; Linden, N. L.; Board, N. L.; Falling Iversen, E.; Terry, S.; Mota, T. M.; Bedir, S.; Clayton, K. L.; Bosque, A.; MacLaren Ehui, L.; Kovacs, C. M.; Betel, D.; Johnson, J. R.; Paiardini, M.; Danesh, A.; Jones, R. B.
10.1101/2024.10.11.617869 — immunology — Posted on 2024-10-15
3090 Cholesterol sulfate prevents maternal-fetal conflict by locally modulating immune reactivity
Hirotani, K.; Kunimura, K.; Maeda, R.; Sugiura, Y.; Nakata, K.; Takahashi, M.; Izumi, Y.; Akiyoshi, S.; Matsubara, K.; Morino, K.; Iwasaki, T.; Tanaka, K.; Aulia, F.; Miyata, K.; Hosokawa, T.; Mori, T.; Ohkawa, Y.; Bamba, T.; Toh, H.; Sasaki, H.; Oda, Y.; Uruno, T.; Kato, K.; Fukui, Y.
10.1101/2024.10.11.617779 — immunology — Posted on 2024-10-15
3091 CD4+ tissue resident memory Th17 cells drive IL-17A-mediated joint pathology in Spondyloarthritis
Liu, F.; Shi, H.; Turner, J. D.; Anscombe, R.; Sekine, T.; Hammitzsch, A.; Agarwal, D.; Mahony, C.; Chen, J.; Kendrick, B.; Du, D.; Tong, Q.; Duan, L.; Dooley, K.; Fang, H.; Korsunsky, I.; Madhu, R.; Cribbs, A.; consortium, C.; Friedrich, M.; Marsden, B. D.; Chen, Y.-L.; Ogg, G.; Adams, A.; Chen, W.; Leonardo, S.; McCann, F. E.; Buckley, C.; Rooney, T.; Freeman, T.; Uhlig, H. H.; Dendrou, C.; Croft, A.; Filer, A.; Bowness, P.; Chen, L.
10.1101/2024.10.11.617865 — immunology — Posted on 2024-10-15
3092 Immunological Profiling in Knee Osteoarthritis: Treg Dysfunction as Key Driver of Pain
Binvignat, M.; Dubois, J.; Marco Salvador, M.; Stys, P.; Pitoiset, F.; Roux, A.; Barbie, M.; Hassler, S.; Lorenzon, R.; Ribet, C.; Mhanna, V.; Vantomme, H.; Adda, L.; Barennes, P.; Coatnoan, N.; Legouge, K.; Aheng, C.; Courties, A.; Minssen, L.; Butte, A. J.; Six, A.; Rosenzwajg, M.; Tchitchek, N.; Berenbaum, F.; Klatzmann, D.; Mariotti-Ferrandiz, E.; Sellam, J.
10.1101/2024.10.12.618016 — immunology — Posted on 2024-10-15
3094 hu.MAP3.0: Atlas of human protein complexes by integration of > 25,000 proteomic experiments
Fischer, S. N.; Claussen, E. R.; Kourtis, S.; Sdelci, S.; Orchard, S.; Hermjakob, H.; Kustatscher, G.; Drew, K.
10.1101/2024.10.11.617930 — systems biology — Posted on 2024-10-15
3096 A Rab-Kinesin12-Fused kinase module couples vesicle delivery and phragmoplast remodelling during cytokinesis in Arabidopsis
Elliott, L.; Kalde, M.; Yamada, M.; Hala, M.; Smertenko, A.; Rozier, F.; Evry, J.; Irani, N.; Jaillais, Y.; Hussey, P. J.; Zarsky, V.; Moore, I.; Kirchhelle, C.
10.1101/2024.10.11.617818 — plant biology — Posted on 2024-10-15
3098 New QTLs involved in the control of stigma position in tomato
Riccini, A.; Olivieri, F.; Farinon, B.; Bitton, F.; Diouf, I. A.; Carretero, Y.; Soler, S.; del Rosario Figas, M.; Prohens, J.; Monforte, A. J.; Granell, A.; Causse, M.; Mazzucato, A.
10.1101/2024.10.11.617926 — plant biology — Posted on 2024-10-15
3099 Rapid onset fibrotic remodeling and ventricular dysfunction induced by phenylephrine involve targeted reprogramming of myocyte and fibroblast transcriptomes
Kimball, T. H.; Gromova, T.; Gehred, N. D.; Chapski, D. J.; Wang, K.; Vaseghi, M.; Fischer, M. A.; Lefer, D. J.; Vondriska, T. M.
10.1101/2024.10.11.617933 — physiology — Posted on 2024-10-15
3100 Radiotherapy triggers pro-angiogenic signaling in human lung
Soulier, J.; Curras-Alonso, S.; Dubail, M.; Laporte, H.; Mallick, A.; Lafouasse, C.; Colin, D.; Cote, J.-F.; Didier, J.; Pouliquen, C.; Benali, A.; Alifano, M.; Durdux, C.; Damotte, D.; Lefevre, M.; Bohec, M.; Cao, K.; Crehange, G.; Verrelle, P.; Girard, N.; Seguin-Givelet, A.; Londono-Vallejo, A.; Fouillade, C.
10.1101/2024.10.11.617840 — cancer biology — Posted on 2024-10-15
3101 Integrated Isoform-Resolved Transcriptomic Analysis of Gossypium barbadense and Gossypium hirsutum Fibers
Tang, J. X.; Gu, X. X.; Ma, Y. X.; Meng, Q. X.; Xie, P. X.; Jiang, S. X.; Hui, L. X.; Lang, Y. X.; Tang, M. X.; Zheng, Y. X.; Yuan, D. X.
10.1101/2024.10.11.617711 — bioinformatics — Posted on 2024-10-15
3105 Deep Learning Enhances Precision of Citrullination Identification in Human and Plant Tissue Proteomes
Gabriel, W.; Meelker Gonzalez, R.; Laposchan, S.; Riedel, E.; Dondar, G.; Poppenberger, B.; Wilhelm, M.; Lee, C.-Y.
10.1101/2024.10.11.617769 — bioinformatics — Posted on 2024-10-15
3108 Dental biofilms contain DNase I-resistant Z-DNA and G-quadruplexes
Evans, D. C. S.; Kristensen, M. F.; Palmen, L. G.; Knap, I.; Tiwari, M. K.; Schlafer, S.; Meyer, R. L.
10.1101/2024.10.13.618059 — microbiology — Posted on 2024-10-15
3110 Microbiome signatures of virulence in the oral-gut-brain axis influence Parkinson's disease and cognitive decline pathophysiology
Clasen, F.; YILDIRIM, S.; Arikan, M.; Garcia-Guevara, F.; Hanoglu, L.; Yilmaz, N. H.; Sen, A.; Demir, T. K.; Yildiz, Z.; Mardinoglu, A.; Uhlen, M.; Shoaie, S.
10.1101/2024.10.14.618175 — microbiology — Posted on 2024-10-15
3113 Leveraging zebrafish embryo phenotypic observations to advance data-driven analyses in toxicology
Michaelis, P.; Klüver, N.; Aulhorn, S.; Bohring, H.; Bumberger, J.; Haase, K.; Kuhnert, T.; Küster, E.; Krüger, J.; Luckenbach, T.; Massei, R.; Nerlich, L.; Petruschke, S.; Schnicke, T.; Schnurpel, A.; Scholz, S.; Schweiger, N.; Sielaff, D.; Busch, W.
10.1101/2024.10.11.617795 — pharmacology and toxicology — Posted on 2024-10-15
3114 Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma
Seetharam, D.; Chandar, J.; Ramsoomair, C. K.; Desgraves, J. F.; Medina, A. A.; Hudson, A. J.; Amidei, A.; Castro, J. R.; Govindarajan, V.; Wang, S.; Zhang, Y.; Sonabend, A. M.; Valdez, M. J. M.; Maric, D.; Govindarajan, V.; Rivas, S. R.; Lu, V. M.; Tiwari, R.; Sharifi, N.; Thomas, E.; Alexander, M.; DeMarino, C.; Johnson, K.; De La Fuente, M. I.; Nasany, R. A.; Noviello, T. M. R.; Ivan, M. E.; Komotar, R. J.; Iavarone, A.; Nath, A.; Heiss, J. D.; Ceccarelli, M.; Chiappinelli, K. B.; Figueroa, M. E.; Bayik, D.; Shah, A. H.
10.1101/2024.10.13.618076 — cancer biology — Posted on 2024-10-15
3115 Molecular and cell phenotype programs in oral epithelial cells directed by co-exposure to arsenic and smokeless tobacco
Das, S.; Thakur, S.; Cahais, V.; Virard, F.; Claeys, L.; Renard, C.; Cuenin, C.; Cros, M.-P.; Keita, S.; Venuti, A.; Sirand, C.; Ghantous, A.; Herceg, Z.; Korenjak, M.; Zavadil, J.
10.1101/2024.10.14.618077 — cancer biology — Posted on 2024-10-15
3117 Efficient indexing and querying of annotations in a pangenome graph
Novak, A. M.; Chung, D.; Hickey, G.; Djebali, S.; Yokoyama, T. T.; Garrison, E.; Narzisi, G.; Paten, B.; Monlong, J.
10.1101/2024.10.12.618009 — bioinformatics — Posted on 2024-10-15
3118 NeKo: a tool for automatic network construction from prior knowledge
Ruscone, M.; Tsirvouli, E.; Checcoli, A.; Turei, D.; Barillot, E.; Saez-Rodriguez, J.; MARTIGNETTI, L.; Flobak, A.; Calzone, L.
10.1101/2024.10.14.618311 — bioinformatics — Posted on 2024-10-15
3119 Toward Automatic Variant Interpretation: Discordant Genetic Interpretation Across Variant Annotations for ClinVar Pathogenic Variants
Chen, A. Y.-A.; Yuan, T.-H.; Huang, J.-H.; Wang, Y.-B.; Hung, T.-M.; Chen, C.-Y.; Hsu, J. S.; Chen, P.-L.
10.1101/2024.10.11.617756 — genomics — Posted on 2024-10-15
3124 DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project
Mariner, B. L.; McCoy, B. M.; Greenier, A.; Brassington, L.; Silkas, E.; Adjangba, C.; Marye, A.; Harrison, B. R.; Bamberger, T.; Algavi, Y.; Muller, E.; Harris, A.; Rout, E.; The Dog Aging Project Consortium, ; Avery, A.; Borenstein, E.; Promislow, D.; Snyder-Mackler, N.
10.1101/2024.10.08.617286 — genomics — Posted on 2024-10-15
3125 Potent Anti-Influenza Synergistic Activity of Theobromine and Arainosine
Lahiri, H.; Israeli, E.; Krugliak, M.; Baso, K.; Britan-Rosich, Y.; Ravins, T.; Arkin, I. T.
10.1101/2024.10.13.618054 — microbiology — Posted on 2024-10-15
3128 CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics Data
Yang, B.; Meng, T.; Wang, X.; Li, J.; Zhao, S.; Wang, Y.; Yi, S.; Zhou, Y.; Zhang, Y.; Li, L.; Guo, L.
10.1101/2024.01.21.576587 — bioinformatics — Posted on 2024-10-15
3130 Testing for age- and sex- specific mitonuclear epistasis in Drosophila
Garlovsky, M. D.; Dobler, R.; Guo, R.; Voigt, S.; Dowling, D. K.; Reinhardt, K.
10.1101/2024.10.10.617520 — evolutionary biology — Posted on 2024-10-15
3131 Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
Mota, C.; Kim, K.; Son, Y. J.; Thak, E. J.; Lee, S.-B.; Kim, J.-E.; Yoon, J.-K.; Kang, M.-H.; Hwang, H.; Bahn, Y.-S.; Alspaugh, A.; Kang, H. A.
10.1101/2024.09.24.610715 — microbiology — Posted on 2024-10-15
3132 RNA sequencing depth guidelines for the study of alternative splicing
Tsoy, O.; Ameling, S.; Franzenburg, S.; Hoffmann, M. D.; Liv-Willuth, L.; Lee, H. K.; Knabl, L.; Furth, P. A.; Voelker, U.; Hennighausen, L.; Baumbach, J.; Kacprowski, T.; List, M.
10.1101/2024.10.09.617406 — bioinformatics — Posted on 2024-10-15
3134 TRPM8 channels control Golgi morphology through an AR-dependent induction of the Scd1 gene and modulation of unsaturated lipid content
Wehbi, M.; GOURIOU, Y.; Borowiec, A.-s.; Geoffray, J.; Badawi, S.; Chouabe, C.; Slomianny, C.; Gordienko, D.; Gonnot, F.; Dewailly, E.; Delcourt, P.; Ferrera, R.; Pais-de-Barros, J.-P.; Kurdi, M.; Heliot, L.; Van Coppenolle, F.; Lemmonier, L.; Prevarskaya, N.; BIDAUX, G.
10.1101/2024.10.14.618203 — cell biology — Posted on 2024-10-15
3135 Individual G-quadruplex targeting with ligand-functionalized CRISPR-Cas9 uncovers transcriptional-dependent functional responses
Nuccio, S. P.; Cadoni, E.; Nikoloudaki, R.; Galli, S.; Ler, A.-J.; Maher, T. E.; Fan, E.; Liu, L. S.; Fullenkamp, C. R.; Schneekloth, J. S.; Di Antonio, M.
10.1101/2024.10.14.618195 — cell biology — Posted on 2024-10-15
3138 Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity
Lee, J. W.; Chen, E. Y.; Hu, T.; Perret, R.; Chaffee, M. E.; Martinov, T.; Mureli, S.; McCurdy, C. L.; Jones, L. A.; Gafken, P. R.; Chanana, P.; Su, Y.; Chapuis, A. G.; Bradley, P.; Schmitt, T. M.; Greenberg, P. D.
10.1101/2024.09.18.612965 — immunology — Posted on 2024-10-15
3139 Functional connectomics reveals general wiring rule in mouse visual cortex
Ding, Z.; Fahey, P. G.; Papadopoulos, S.; Wang, E. Y.; Celii, B.; Papadopoulos, C.; Chang, A.; Kunin, A.; Tran, D.; Fu, J.; Ding, Z.; Patel, S.; Ntanavara, L.; Froebe, R.; Ponder, K.; Muhammad, T.; Bae, J. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Cobos, E.; Dorkenwald, S.; Elabbady, L.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Schneider-Mizell, C. M.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong,
10.1101/2023.03.13.531369 — neuroscience — Posted on 2024-10-15
3140 Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma
Karnan, S.; Ota, A.; Hasan, M. N.; Murakami, H.; Rahman, M. L.; Wahiduzzaman, M.; Shihan, M. T. A.; Jahan, N.; Vu, L. Q.; Hanamura, I.; Inoko, A.; Riku, M.; Ito, H.; Kaneko, Y.; Lin, Y.; Hyodo, T.; Konishi, H.; Tsuzuki, S.; Hosokawa, Y.
10.1101/2024.07.14.603191 — cancer biology — Posted on 2024-10-15
3142 Liver CYP4A autophagic-lysosomal degradation (ALD): A major role for the autophagic receptor SQSTM1/p62 through an uncommon target interaction site
He, L.; Kwon, D.; Trnka, M. J.; Liu, Y.; Yang, J.; Li, K.; Totah, R. A.; Johnson, E. F.; Burlingame, A. L.; Correia, M. A.
10.1101/2024.10.14.618315 — cell biology — Posted on 2024-10-14
3143 Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder
Ghoochani, A.; Heiby, J. C.; Rawat, E. S.; Medoh, U. N.; Di Fraia, D.; Dong, W.; Gastou, M.; Nyame, K.; Laqtom, N. N.; Gomez-Ospina, N.; Ori, A.; Abu-Remaileh, M.
10.1101/2024.10.14.618295 — cell biology — Posted on 2024-10-15
3144 Spatial organization of supercoil dynamics during DNA replication
Kusano, Y.; Shinkai, S.; Nozawa, R.-S.; Sun, J.; Onami, S.; Tashiro, S.; Hirota, T.
10.1101/2024.10.14.618193 — cell biology — Posted on 2024-10-15
3145 HIF-1α regulates mitochondrial function in bone marrow-derived macrophages, but not in tissue-resident alveolar macrophages
Woods, P. S.; Cetin-Atalay, R.; Meliton, A. Y.; Sun, K. A.; Shamaa, O. R.; Shin, K. W. D.; Tian, Y.; Haugen, B.; Hamanaka, R. B.; Mutlu, G. M.
10.1101/2024.10.14.618294 — cell biology — Posted on 2024-10-15
3146 Identification of lipid senolytics targeting senescent cells through ferroptosis induction
Zhang, L. J.; Salekeen, R.; Soto-Palma, C.; Elsallabi, O.; Ye, H.; Hughes, B.; Zhang, B.; Nunes, A.; Lee, K.; Xu, W.; Mohamed, A.; Piepgras, E.; Mcgowan, S.; Angelini, L.; O'Kelly, R.; Han, X.; Niedernhofer, L. J.; Robbins, P.
10.1101/2024.10.14.618023 — cell biology — Posted on 2024-10-15
3147 In vitro inhibition of the CFTR ion channel in the cervix thickens cervical mucus
Looney, R. J.; Roberts, M.; Markovetz, M.; Godiah, R.; Yao, S.; Golgotiu, K.; Wei, S.; Cellucci, C.; Han, L.
10.1101/2024.10.14.618249 — cell biology — Posted on 2024-10-15
3148 Beta-hairpin Mechanism of Autoinhibition and Activation in the Kinesin-2 Family
Webb, S.; Toropova, K.; Mukhopadhyay, A. G.; Nofal, S. D.; Roberts, A. J.
10.1101/2024.10.14.618219 — cell biology — Posted on 2024-10-15
3149 Virulence-linked adhesin drives mutualist colonization of the bee gut via biofilm formation
Lariviere, P. J.; Ashraf, A. H. M. Z.; Gifford, I.; Tanguma, S. L.; Barrick, J. E.; Moran, N. A.
10.1101/2024.10.14.618124 — microbiology — Posted on 2024-10-14
3150 Characterisation of Pseudomonas aeruginosas metal-responsive TonB-dependent transporters
Ferry, M.; Ferriz, H.; Sharp, C.; Paschalidis, C.; Boutant, E.; Schalk, I. J.; Cunrath, O.
10.1101/2024.10.14.618150 — microbiology — Posted on 2024-10-14
3151 16S rRNA gene sequencing for bacterial identification and infectious disease diagnosis
Li, M.-N.; Han, Q.; Wang, N.; Wang, T.; You, X.-M.; Zhang, S.; Zhang, C.-C.; Shi, Y.-Q.; Qiao, P.-Z.; Man, C.-L.; Feng, T.; Li, Y.-Y.; Zhu, Z.; Quan, K.-J.; Xu, T.-L.; Zhang, G. F.
10.1101/2024.10.14.618149 — microbiology — Posted on 2024-10-14
3153 Structure of the turnip yellows virus particles. How is the readthrough domain exposed on the capsid surface?
Lai-Kee-Him, J.; Trapani, S.; Boissinot, S.; Reinbold, C.; Fallet, C.; Ancelin, A.; Lecorre, F.; Hoh, F.; Ziegler-Graff, V.; Brault, V.; Bron, P.
10.1101/2024.10.14.617924 — microbiology — Posted on 2024-10-14
3159 Structural dynamics of the intrinsically disordered linker region of cardiac troponin T
Cubuk, J.; Greenberg, L.; Greenberg, A. E.; Emenecker, R. J.; Stuchell-Brereton, M. D.; Holehouse, A. S.; Soranno, A. J.; Greenberg, M. J.
10.1101/2024.05.30.596451 — biophysics — Posted on 2024-10-14
3162 Single-cell and spatial detection of senescent cells using DeepScence
Qu, Y.; Dong, R.; Gu, L.; Chan, C.; Xie, J.; Glass, C.; Wang, X.-F.; Nixon, A.; Ji, Z.
10.1101/2023.11.21.568150 — bioinformatics — Posted on 2024-10-14
3165 Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation
Niedner-Boblenz, A.; Monecke, T.; Hennig, J.; Klostermann, M.; Hofweber, M.; Davydova, E.; Gerber, A. P.; Anosova, I.; Mayer, W.; Mueller, M.; Heym, R.; Janowski, R.; Paillart, J.-C.; Dormann, D.; Zarnack, K.; Sattler, M.; Niessing, D.
10.1101/2024.03.27.586925 — biochemistry — Posted on 2024-10-14
3167 A Constitutive Heterochromatic Region Shapes Genome Organization and Impacts Gene Expression in Neurospora crassa
Reckard, A. T.; Pandeya, A.; Voris, J. M.; Gonzalez Cruz, C. G.; Oluwadare, O. E.; Klocko, A. D.
10.1101/2024.06.07.597955 — genomics — Posted on 2024-10-14
3168 Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function
Paddar, M. A.; Wang, F.; Trosdal, E.; Hendrix, E.; He, Y.; Salemi, M. R.; Mudd, M.; Jia, J.; Duque, T.; Javed, R.; Phinney, B. S.; Deretic, V.
10.1101/2024.07.10.602886 — cell biology — Posted on 2024-10-14
3169 Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei
Das, S.; Unhale, T.; Marinach, C.; Valeriano Alegria, B. d. C.; Roux, C.; Madry, H.; Mohand Oumoussa, B.; Amino, R.; Iwanaga, S.; Briquet, S.; Silvie, O.
10.1101/2024.10.14.618196 — microbiology — Posted on 2024-10-14
3170 Farm exposure is associated with human breast milk immune profile and microbiome
Swaney, M. H.; Steidl, O.; Tackett, A.; Fye, S.; Lee, K.; Ong, I. M.; Bendixsen, C.; Spicer, G.; DeLine, J.; Gern, J. E.; Lucey, J.; Seroogy, C.; Kalan, L.; Singh, A. M.
10.1101/2024.10.14.618271 — microbiology — Posted on 2024-10-14
3172 Improving the annotation of amino acid biosynthesis pathways: GapMind 2024
Price, M. N.; Shiver, A. L.; Day, L. A.; Bejar, M. T.; Lesea, H. P.; Owens, T. K.; Deutschbauer, A.; Arkin, A. P.
10.1101/2024.10.14.618325 — microbiology — Posted on 2024-10-14
3173 Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa
Huang, J.; Sun, Y.; Chen, F.; Li, S.; Han, L.; Li, J.; He, Z.; Hua, C.; Yao, C.; Li, T.; Lu, B.; Chang, Y.-F.; Deng, X.
10.1101/2024.10.14.618254 — microbiology — Posted on 2024-10-14
3174 Antarctic geothermal soils exhibit an absence of regional habitat generalist microorganisms
Noell, S. E.; Abbaszadeh, J.; Richards, H.; Labat Saint Vincent, M.; Lee, C. K.; Herbold, C. W.; Stott, M. B.; Cary, S. C.; McDonald, I. R.
10.1101/2024.06.06.597824 — microbiology — Posted on 2024-10-14
3176 The Prevalence of Killer Yeasts in the Gardens of Fungus-Growing Ants and the Discovery of Novel Killer Toxin named Ksino.
Bizarria, R.; Creagh-Grave, J.; Badigian, T.; Santos, R. A.; Coss, S.; Tekle, R.; Fredstrom, N.; Ytreberg, F. M.; Dunham, M. J.; Rodrigues, A.; Rowley, P. A.
10.1101/2024.10.14.618321 — microbiology — Posted on 2024-10-14
3178 Immune cells promote paralytic disease in mice infected with enterovirus D68
Woods Acevedo, M. A.; Lan, J.; Maya, S.; Jones, J. E.; Williams, J. V.; Culler Freeman, M.; Dermody, T. S.
10.1101/2024.10.14.618341 — microbiology — Posted on 2024-10-14
3179 Collective β-lactam resistance in Escherichia coli due to β-lactamase release upon cell death
Gross, R.; Mungan, M.; Das, S. G.; Yüksel, M.; Maier, B.; Bollenbach, T.; Krug, J.; de Visser, J. A. G. M.
10.1101/2024.10.14.618215 — microbiology — Posted on 2024-10-14
3181 Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations
Feczko, E. J.; Stoyell, S. M.; Moore, L. A.; Alexopoulos, D.; Bagonis, M.; Barrett, K.; Bower, B.; Cavender, A.; Chamberlain, T. A.; Conan, G.; Day, T. K.; Goradia, D.; Graham, A.; Heisler-Roman, L.; Hendrickson, T. J.; Houghton, A.; Kardan, O.; Kiffmeyer, E. A.; Lee, E. G.; Lundquist, J. T.; Lucena, C.; Martin, T.; Mummaneni, A.; Myricks, M.; Narnur, P.; Perrone, A. J.; Reiners, P.; Rueter, A. R.; Saw, H.; Styner, M.; Sung, S.; Tiklasky, B.; Wisnowski, J. L.; Yacoub, E.; Zimmermann, B.; Smyser, C. D.; Rosenberg, M. D.; Fair, D. A.; Elison, J. T.
10.1101/2024.10.02.616147 — neuroscience — Posted on 2024-10-14
3182 Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission
White, K. I.; Khan, Y. A.; Qiu, K.; Balaji, A.; Couoh-Cardel, S.; Esquivies, L.; Pfuetzner, R. A.; Diao, J.; Brunger, A. T.
10.1101/2024.10.11.617886 — neuroscience — Posted on 2024-10-14
3186 Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy
Saez-Calveras, N.; Vaquer-Alicea, J.; White, C. L.; Tak, Y.; Cosentino, S.; Faust, P. L.; Louis, E. D.; Diamond, M. I.
10.1101/2024.10.12.617973 — pathology — Posted on 2024-10-14
3188 Binding Site Maturation Modulated by Molecular Density Underlies Ndc80 Binding to Kinetochore Receptor CENP-T
Tarasovetc, E. V.; Sissoko, G. B.; Maiorov, A.; Mukhina, A. S.; Ataullakhanov, F. I.; Cheeseman, I. M.; Grishchuk, E. L.
10.1101/2024.02.25.581584 — biophysics — Posted on 2024-10-14
3189 Multilevel irreversibility reveals higher-order organisation of non-equilibrium interactions in human brain dynamics
Nartallo-Kaluarachchi, R.; Bonetti, L.; Fernandez-Rubio, G.; Vuust, P.; Deco, G.; Kringelbach, M. L.; Lambiotte, R.; Goriely, A.
10.1101/2024.05.02.592195 — biophysics — Posted on 2024-10-14
3195 CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles
Pierce, C. A.; Suryoraharjo, K. E.; Robertson, I. H.; Su, X.; Hatchett, D. B.; Shin, A.; Adams, K. N.; Berthier, E.; Thongpang, S.; Ogata, A. F.; Theberge, A. B.; Sohn, L. L.
10.1101/2024.10.09.617508 — bioengineering — Posted on 2024-10-14
3199 Learning is a fundamental source of behavioral individuality
Manna, R.; Brea, J.; Braga, G. V.; Modirshanechi, A.; Tomic, I.; Jaksic, A. M.
10.1101/2024.08.30.610528 — animal behavior and cognition — Posted on 2024-10-14
3203 An in vivo screen for proteolytic switches that can mediate Notch activation
Baker, F.; Harman, J.; Jordan, T.; Walton, B.; Ajamu-Johnson, A.; Alashqar, R.; Bhikot, S.; Struhl, G.; Langridge, P. D.
10.1101/2024.07.10.602225 — cell biology — Posted on 2024-10-14
3205 A fine kinetic balance of interactions directs transcription factor hubs to genes
Fallacaro, S.; Mukherjee, A.; Ratchasanmuang, P.; Zinski, J.; Shankta, K.; Mir, M.; Haloush, Y. I.
10.1101/2024.04.16.589811 — molecular biology — Posted on 2024-10-14
3206 Green synthesized silver nanoparticles from Moringa: Potential for preventative treatment of SARS-CoV-2 contaminated water
Shittu, M. O.; Bello, A. J.; Ebunoluwa, O. B.; Ayorinde, R. O.; Onyepeju, N.; Shaibu, J. O.; Adewole, A. R.; Adewole, A. O.; Adedeji, O.; Akinnusi, O. O.; Oladapo, O. B.; Popoola, T. S.; Arotiba, O. M.; Minari, J. B.; Adams, L. A.; Okpuzor, J.
10.1101/2024.10.12.617998 — microbiology — Posted on 2024-10-14
3210 Foundry-fabricated dual-color nanophotonic neural probes for photostimulation and electrophysiological recording
Roszko, D. A.; Chen, F.-D.; Straguzzi, J.; Wahn, H.; Xu, A.; McLaughlin, B.; Yin, X.; Chua, H.; Luo, X.; Lo, G.-Q.; Siegle, J. H.; Poon, J. K. S.; Sacher, W. D.
10.1101/2024.09.25.614961 — neuroscience — Posted on 2024-10-14
3211 Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis.
Christopher, C. J.; Morgan, K. H.; Tolleson, C. M.; Trudell, R.; Fernandez-Romero, R.; Rice, L.; Abiodun, B. A.; Vickery, Z.; Jones, K.; Woodall, B. M.; Nagy, C.; Mieczkowski, P. A.; Bowen, G.; Campagna, S. R.; Ellis, J. C.
10.1101/2024.10.13.615818 — neuroscience — Posted on 2024-10-14
3212 Variations of autonomic arousal mediate the reportability of mind-blanking occurrences
Boulakis, P. A.; Simos, N. J.; Zoi, S.; Mortaheb, S.; Schmidt, C.; Raimondo, F.; Demertzi, A.
10.1101/2024.03.26.586648 — neuroscience — Posted on 2024-10-14
3216 Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
Prithiviraj, S.; Garcia Garcia, A.; Linderfalk, K.; Yiguang, B.; Ferveur, S.; Falck, L. N.; Subramaniam, A.; Mohlin, S.; Gil, D. H.; Dupard, S. J.; Zacharaki, D.; Raina, D. B.; Bourgine, P. E.
10.1101/2023.07.28.550935 — bioengineering — Posted on 2024-10-14
3217 Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy
Wang, Z.; Zhao, R.; Wagenaar, D. A.; Espino, D.; Sheintuch, L.; Benshlomo, O.; Kang, W.; Lee, C.; Schmidt, W.; Pammar, A.; Zhu, E.; Wang, J.; Wong, G. C. L.; Liang, R.; Golshani, P.; Hsiai, T.; Gao, L.
10.1101/2024.03.23.586416 — bioengineering — Posted on 2024-10-14
3218 Synthesis and Evaluation of Carmofur Analogs as Antiproliferative Agents, Inhibitors to the Main Protease (Mpro) of SARS-CoV-2, and Membrane Rupture-Inducing Agents
Gu, T.; Lu, A.; Wang, X.; Brahan, N.; Xu, L.; Zhang, L.; Su, K.; Seow, K.; Vu, J.; Luk, C.; Lee, Y.; Raman, A.; Pazzi, J.; Njoo, E.
10.1101/2024.10.11.617727 — biochemistry — Posted on 2024-10-14
3220 rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload
Leggieri, A.; Judit Garcia-Gonzalez, J.; Hosseinian, S.; Ashdown, P.; Anagianni, S.; Wang, X.; Havelange, W.; Fernandez-Castillo, N.; Cormand, B.; Brennan, C. H.
10.1101/2024.10.09.616976 — genetics — Posted on 2024-10-14
3221 Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium.
Dirvin, B. G.; Noh, H.; Tomassoni, L.; Cao, D.; Zhou, Y.; Ke, X.; Qian, J.; Schotsaert, M.; Garcia-Sastre, A.; Karan, C.; Califano, A.; Cardoso, W. V.
10.1101/2024.10.11.617898 — cell biology — Posted on 2024-10-14
3224 Optical imaging of treatment-naive human NSCLC reveals changes associated with metastatic recurrence
Diaz, P. M.; Ivers, J. D.; Byrum, S. D.; Quick, C. M.; Arnaoutakis, K.; Quinn, K. P.; Rajaram, N.
10.1101/2024.10.14.618213 — cancer biology — Posted on 2024-10-14
3225 Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes
Atser, M. G.; Wenyonu, C. D.; Rowe, E. M.; Leung, C. L. K.; Cen, H. H.; Queathem, E. D.; Liu, L. T.; Moravcova, R.; Rogalski, J.; Perrin, D.; Crawford, P.; Foster, L. J.; Alcazar, A.; Johnson, J. D.
10.1101/2024.10.14.618123 — biochemistry — Posted on 2024-10-14
3226 Tau load in select brainstem neurons predicts the severity and nature of balance deficits in the absence of cell death
Zhu, Y.; Gelnaw, H.; Leary, P.; Raghuraman, R.; Kamath, N.; Kraja, A.; Liu, J.; Bai, Q.; Higashijima, S.-i.; Burton, E. A.; Schoppik, D.
10.1101/2024.10.14.618073 — neuroscience — Posted on 2024-10-14
3227 Cataract induction in an arthropod reveals how lens crystallins contribute to the formation of biological glass
Mitra, A. T.; Rathore, S.; Jester, A.; Hyland-Brown, R.; Hassert, J.; Benoit, J. B.; Buschbeck, E. K.
10.1101/2024.10.14.618264 — neuroscience — Posted on 2024-10-14
3229 Identification of Phosphotyrosine-Mutant Desmin in Human Pancreatic Cancer
Kendrick, N. C.; Darie, C. C.; Hoelter, M. C.; Koll, A. A.; Johansen, J. J.
10.1101/2024.10.14.618246 — cancer biology — Posted on 2024-10-14
3231 Assembloid model to study loop circuits of the human nervous system
Miura, Y.; Kim, J.-i.; Jurjut, O.; Kelley, K. W.; Yang, X.; Chen, X.; Thete, M. V.; Revah, O.; Cui, B.; Pachitariu, M.; Pasca, S. P.
10.1101/2024.10.13.617729 — neuroscience — Posted on 2024-10-14
3237 Toxicokinetics for organ-on-chip devices
Hermann, N. G.; Ficek, R. A.; Markov, D. A.; McCawley, L. J.; Hutson, M. S.
10.1101/2024.10.10.617253 — bioengineering — Posted on 2024-10-14
3238 Insights into the Molecular Mechanism of Pulmonary Vein Stenosis in Pediatric Patients
Kalustian, A. B.; Ji, P.; Wadhwa, L.; Caldarone, C.; Bansal, M.; Qureshi, A.; Heinle, J. S.; Birla, R.
10.1101/2024.10.09.617404 — genomics — Posted on 2024-10-14
3239 Decoding sequence determinants of gene expression in diverse cellular and disease states
Lal, A.; Karollus, A.; Gunsalus, L.; Garfield, D.; Nair, S.; Tseng, A. M.; Gordon, M. G.; Collier, J. L.; Diamant, N.; Biancalani, T.; Corrada Bravo, H.; Scalia, G.; Eraslan, G.
10.1101/2024.10.09.617507 — genomics — Posted on 2024-10-14
3240 Testing for age- and sex- specific mitonuclear epistasis in Drosophila
Garlovsky, M. D.; Dobler, R.; Guo, R.; Voigt, S. D.; Dowling, D. K.; Reinhardt, K.
10.1101/2024.10.10.617520 — evolutionary biology — Posted on 2024-10-14
3241 Multi-modal profiling identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers for response to R-CHOP therapy in human DLBCL
Yu, S.; Kong, H.; Luo, H.; zhao, x.; Zhu, G.; Feng, X.; Yang, J.; Wu, X.; Dai, Y.; Wu, C.; Wang, J.; Cao, D.; Xu, Y.; Jiang, H.; Wang, P.
10.1101/2024.10.10.617515 — immunology — Posted on 2024-10-14
3244 SOX10 and microRNAs: decoding their interplay in regulating melanoma plasticity
Lai, X.; Luan, C.; Zhang, Z.; Wessely, A.; Heppt, M.; Berking, C.; Vera, J.
10.1101/2024.10.09.617381 — systems biology — Posted on 2024-10-14
3248 Shaping Kale Morphology and Physiology Using Different LED Light Recipes
Scandola, S.; Grubb, L. E.; Castillo, B.; Iliscupidez, L.; Kennedy, C.; Boyce, N.; Uhrig, R. G.
10.1101/2024.10.10.617428 — plant biology — Posted on 2024-10-14
3252 Lead as a toxic environmental toxicant in models of synucleinopathies
Shvachiy, L.; Amaro-Leal, A.; Machado, F.; Rocha, I.; Geraldes, V.; Outeiro, T. F.
10.1101/2024.10.10.617554 — physiology — Posted on 2024-10-14
3254 Identification of potential sepsis therapeutic drugs using a zebrafish rapid screening approach
Widder, M. W.; Carbaugh, C.; van der Schalie, W.; Miller, R.; Brennan, L.; Moore, A.; Campbell, R.; Akers, K.; Ressner, R.; Martin, M.; Madejczyk, M.; Dancy, B.; Lee, P.; Lanteri, C.
10.1101/2024.10.09.617431 — pharmacology and toxicology — Posted on 2024-10-14
3255 Characterization of AZ12464237 as a high affinity, non-nucleotide antagonist radioligand for the P2Y12 receptor
Steen, J.; Tousiaki, E.-N.; Kingston, L.; van der Wildt, B.; Lenart, N.; Beaino, W.; Verlaan, M.; Zarzycka, B.; Zinnhardt, B.; Denes, A.; Gobbi, L.; de Esch, I. J. P.; Elmore, C. S.; Windhorst, A. D.; Honer, M.; Leurs, R.
10.1101/2024.10.10.617599 — pharmacology and toxicology — Posted on 2024-10-14
3261 prolfquapp - A User-Friendly Command-Line Tool Simplifying Differential Expression Analysis in Quantitative Proteomics
Wolski, W. E.; Grossmann, J.; Schwarz, L.; Leary, P.; Turker, C.; Nanni, P.; Schlapbach, R.; Panse, C.
10.1101/2024.10.09.617391 — bioinformatics — Posted on 2024-10-14
3263 CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles
Pierce, C.; Suryoraharjo, K.; Robertson, I. H.; Su, X.; Hatchett, D. B.; Shin, A.; Adams, K. N.; Berthier, E.; Thongpang, S.; Ogata, A.; Theberge, A. B.; Sohn, L. L.
10.1101/2024.10.09.617508 — bioengineering — Posted on 2024-10-14
3264 Chromatin interaction maps of human arterioles reveal new mechanisms for the genetic regulation of blood pressure
Liu, Y.; Pandey, R.; Qiu, Q.; Liu, P.; Xue, H.; Wang, J.; Therani, B.; Ying, R.; Usa, K.; Grzybowski, M.; Yang, C.; Mishra, M.; Greene, A. S.; Cowley, A. W.; Rao, S.; Geurts, A. M.; Widlansky, M. E.; Liang, M.
10.1101/2024.10.09.617511 — genomics — Posted on 2024-10-14
3265 Limitations of ad hoc genotyping in detecting ash dieback tolerance in Fraxinus excelsior
Szukala, A.; Unger, G.; Trujillo-Moya, C.; Geburek, T.; Kirisits, T.; Schueler, S.; Konrad, H.
10.1101/2024.10.11.617393 — genetics — Posted on 2024-10-14
3267 Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control
Longo, J.; DeCamp, L. M.; Oswald, B. M.; Teis, R.; Reyes-Oliveras, A.; Dahabieh, M. S.; Ellis, A. E.; Vincent, M. P.; Damico, H.; Gallik, K. L.; Compton, S. E.; Capan, C. D.; Williams, K. S.; Esquibel, C. R.; Madaj, Z. B.; Lee, H.; Roy, D. G.; Krawczyk, C. M.; Haab, B. B.; Sheldon, R. D.; Jones, R. G.
10.1101/2024.10.10.617261 — immunology — Posted on 2024-10-14
3269 Back to the Future: Environmental genomic selection to take advantage of polygenic local adaptation
Halpin-McCormick, A.; Campbell, Q.; Negrao, S.; Morrell, P. L.; Hubner, S.; Neyhart, J.; Kantar, M. B.
10.1101/2024.10.09.617488 — plant biology — Posted on 2024-10-14
3270 The kinetics of bedaquiline diffusion in tuberculous cavities opens a window for emergence of resistance.
Bustion, A. E.; Ernest, J. P.; Kaya, F.; Silva, C.; Sarathy, J.; Blanc, L.; Imperial, M.; Gengenbacher, M.; Xie, M.; Zimmerman, M.; Robertson, G. T.; Weiner, D.; Via, L. E.; Barry, C. E.; Savic, R. M.; Dartois, V.
10.1101/2024.10.09.617456 — pharmacology and toxicology — Posted on 2024-10-14
3272 The mechanical and sensory signature of plant-based and animal meat
St. Pierre, S. R.; Darwin, E. C.; Adil, D.; Aviles, M. C.; Date, A. M.; Dunne, R.; Lall, Y.; Vallecillo, M. P.; Medina, V. A. P.; Linka, K.; Levenston, M. E.; Kuhl, E.
10.1101/2024.04.25.591207 — bioengineering — Posted on 2024-10-14
3275 Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes
Valencia, D. A.; Koeberlein, A. N.; Nakano, H.; Rudas, A.; Harui, A.; Spencer, C.; Nakano, A.; Quinlan, M. E.
10.1101/2024.10.13.618125 — cell biology — Posted on 2024-10-14
3276 Using CRISPR barcoding as a molecular clock to capture dynamic processes at single-cell resolution
Andres-Lopez, Y.; Santambrogio, A.; Kafetzopoulos, I.; Todd, C.; Alda-Catalinas, C.; Clark, S. J.; Reik, W.; Hernando-Herraez, I.
10.1101/2024.10.14.618192 — cell biology — Posted on 2024-10-14
3282 Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons
Costa, A. C.; Murillo, B. R.; Bessa, R.; Ribeiro, R.; Ferreira da Silva, T.; Porfirio-Rodrigues, P.; Martins, G. G.; Brites, P.; Kneussel, M.; Misgeld, T.; Brill, M. S.; Sousa, M. M.
10.1101/2024.10.10.617525 — neuroscience — Posted on 2024-10-14
3283 IGF-1 IMPACTS NEOCORTICAL INTERNEURON CONNECTIVITY IN EPILEPTIC SPASM GENERATION AND RESOLUTION
Ballester-Rosado, C. J.; Le, J. T.; Lam, T.; Anderson, A. E.; Frost, J. D.; Swann, J. W.
10.1101/2024.10.13.618035 — neuroscience — Posted on 2024-10-14
3284 Human brain changes after first psilocybin use
Lyons, T.; Spriggs, M.; Kerkela, L.; Rosas, F.; Roseman, L.; Timmermann, C.; Oestreich, L.; Pagni, B.; Zeifman, R.; Hampshire, A.; Trender, W.; Douglas, H.; Girn, M.; Godfrey, K.; Kettner, H.; Sharif, F.; Espasiano, L.; Gazzaley, A.; Wall, M.; Erritzoe, D.; Nutt, D.; Carhart-Harris, R.
10.1101/2024.10.11.617955 — neuroscience — Posted on 2024-10-14
3285 CONTROL OF OROBANCHE CUMANA WALLR: RESEARCH ON SUSTAINABILITY OF SUNFLOWER HYBRIDS AND STRATEGIES FOR PARASITE PROTECTION
Khablak, S.; Bondareva, L.; Dolia, M.; Blume, Y.; Tymoshchuk, T.; Mrynskyi, I.; Hrytsiuk, N.; Spychak, V.
10.1101/2024.10.12.617968 — plant biology — Posted on 2024-10-14
3287 Dual specificity phosphate 1 (DUSP1) as a non-invasive circulating biomarker candidate in preeclampsia
Andrieu, J.; Donet, A.; Cocallemen, J. F.; Charbonnier, G.; Resseguier, N.; Paganini, J.; Mege, J.-L.; Mezouar, S.; Bretelle, F.
10.1101/2024.10.12.618015 — pathology — Posted on 2024-10-14
3288 Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy
Saez-Calveras, N.; Vaquer-Alicea, J.; White, C. L.; Tak, Y.; Cosentino, S.; Faust, P. L.; Louis, E. D.; Diamond, M. I.
10.1101/2024.10.12.617973 — pathology — Posted on 2024-10-14
3290 Fentanyl reinforcement history has sex-specific effects on multi-step decision-making
Garr, E.; Cheng, Y.; Castell, L.; Dong, A.; Shuai, C.; Wang, Y.; Min, J.; Camhi, Z.; Nay, A.; Malloy, N.; Janak, P. H.
10.1101/2024.10.10.617707 — animal behavior and cognition — Posted on 2024-10-14
3293 Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis.
Ellis, J. C.; Christopher, C. J.; Morgan, K. H.; Tolleson, C. M.; Trudell, R.; Fernandez-Romero, R.; Rice, L.; Abiodun, B. A.; Vickery, Z.; Jones, K.; Woodall, B. M.; Nagy, C.; Mieczkowski, P. A.; Campagna, S. R.; Bowen, G.; MIND Consortium,
10.1101/2024.10.13.615818 — neuroscience — Posted on 2024-10-14
3296 Late Quaternary climatic impact on the woodland strawberry genome: a perennial herb's tale
Toivainen, T.; Salonen, J. S.; Kirshner, J.; Lembinen, S.; De Kort, H.; Lyyski, A.; Edger, P. P.; Hilmarsson, H. S.; Hallsson, J. H.; Sargent, D. J.; Olbricht, K.; Sanchez-Sevilla, J. F.; Jaakola, L.; Stenberg, J. A.; Duralija, B.; Labokas, J.; Vare, H.; Salojarvi, J.; Auvinen, P.; Pose, D.; Albert, V. A.; Hytonen, T.
10.1101/2024.10.09.617376 — plant biology — Posted on 2024-10-14
3298 Examining perfluorohexane sulfonate (PFHxS) impacts on sensorimotor and circadian rhythm development
Ferdous, S. R.; Rojas, A.; Frank, C.; Sabatini, H. M.; Luo, X.; Sharma, S.; Thummel, R.; Chouinard, C.; Dasgupta, S.
10.1101/2024.10.08.617320 — pharmacology and toxicology — Posted on 2024-10-14
3299 Caging of membrane-to-cortex attachment proteins can trigger cellular symmetry breaking
Dar, S.; Moreno, R. T.; Palaia, I.; Gopalan, A. B.; Sun, Z. G.; Strauss, L.; Springer, R.; Belmonte, J. M.; Foster, S. K.; Murrell, M.; Ejsing, C. S.; Saric, A.; Leptin, M.; Diz-Munoz, A.
10.1101/2024.10.14.618153 — biophysics — Posted on 2024-10-14
3301 ATP burst is the dominant driver of antibiotic lethality in Mycobacteria
Lodhiya, T.; Palande, A.; Veeram, A.; Larrouy-Maumus, G.; Beste, D. J.; Mukherjee, R.
10.1101/2023.09.11.557291 — microbiology — Posted on 2024-10-14
3304 Cryo-ET of actin cytoskeleton and membrane structure in lamellipodia formation using optogenetics
Inaba, H.; Imasaki, T.; Aoyama, K.; Yoshihara, S.; Takazaki, H.; Kato, T.; Goto, H.; Mitsuoka, K.; Nitta, R.; Nakata, T.
10.1101/2024.08.13.607852 — cell biology — Posted on 2024-10-14
3305 FiNNpy 2.0: Fast MEG source reconstruction
Crompton, D.; Keerthi, P.; Milosevic, L.; Scherer, M.
10.1101/2024.10.11.617925 — neuroscience — Posted on 2024-10-14
3307 Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG
Gil Avila, C.; May, E. S.; Bott, F. S.; Tiemann, L.; Hohn, V.; Heitmann, H.; Zebhauser, P. T.; Gross, J.; Ploner, M.
10.1101/2024.07.23.604775 — neuroscience — Posted on 2024-10-14
3308 The evolution of root hydraulic traits in wheat over 100 years of breeding
Baca Cabrera, J. C.; Vanderborght, J.; Boursiac, Y.; Behrend, D.; Gaiser, T.; Nguyen, T. H.; Lobet, G.
10.1101/2024.10.10.617660 — plant biology — Posted on 2024-10-14
3309 Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification
Supatmi, S.; Lam, L. P. Y.; Yamamoto, S.; Afifi, O. A.; Ji, P.; Osakabe, Y.; Osakabe, K.; Umezawa, T.; Tobimatsu, Y.
10.1101/2024.10.08.617307 — plant biology — Posted on 2024-10-14
3310 A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness
Debnath, A. J.; Harencar, L.; Kucka, M.; Kovar, M.; Ivanisova, E.; Mistrikova, V.; Gazo, J.; Razna, K.
10.1101/2024.10.10.617604 — plant biology — Posted on 2024-10-14
3312 Plant plasmodesmata bridges form through ER-driven incomplete cytokinesis
Li, Z. P.; Moreau, H.; Petit, J. D.; Souza-Moraes, T.; Smokvarska, M.; Perez-Sancho, J.; Petrel, M.; Decoeur, F.; Brocard, L.; Chambaud, C.; Grison, M.; Paterlini, A.; Hoornaert, L.; Joshi, A. S.; Gontier, E.; Prinz, W. A.; Jaillais, Y.; Taly, A.; Campelo, F.; Caillaud, M.-c.; Bayer, E. M.
10.1101/2023.12.12.571296 — plant biology — Posted on 2024-10-14
3316 Quantifying relative sponginess: a high-resolution model of landscape water retention as an ecosystem service
Evans, P. M.; Dussaillant, A.; Varma, V. M.; Redhead, J. W.; Pywell, R. F.; Storkey, J.; Mead, A.; Bullock, J. M.
10.1101/2024.10.11.617771 — ecology — Posted on 2024-10-13
3318 Elevated developmental temperatures below the lethal limit reduce Aedes aegypti fertility
Peklanska, M.; van Heerwaarden, B.; Hoffmann, A. A.; Nouzova, M.; Sima, R.; Ross, P. A.
10.1101/2024.10.10.617713 — ecology — Posted on 2024-10-14
3319 PhenoVision: A framework for automating and delivering research-ready plant phenology data from field images
Dinnage, R.; Grady, E.; Neal, N.; Deck, J.; Denny, E.; Walls, R.; Seltzer, C.; Guralnick, R.; Li, D.
10.1101/2024.10.10.617505 — ecology — Posted on 2024-10-14
3322 RNA sequencing depth guidelines for the study of alternative splicing
Tsoy, O.; Ameling, S.; Franzenburg, S.; Hoffmann, M. D.; Liv-Willuth, L.; Lee, H. K.; Knabl, L.; Furth, P. A.; Voelker, U.; Hennighausen, L.; Baumbach, J.; Kacprowski, T.; List, M.
10.1101/2024.10.09.617406 — bioinformatics — Posted on 2024-10-13
3324 UniScore, a unified and universal measure for peptide identification by multiple search engines
Tabata, T.; Yoshizawa, A. C.; Ogata, K.; Chang, C.-H.; Araki, N.; Sugiyama, N.; Ishihama, Y.
10.1101/2024.10.09.617445 — bioinformatics — Posted on 2024-10-13
3326 Systematic Mining of gut microbiota biomarkers for IBD
Zhang, Y.; Lai, W.; Wang, M.; Lai, S.; Luo, Q.; Luo, Q.; Yang, F. l.
10.1101/2024.10.10.617522 — bioinformatics — Posted on 2024-10-13
3327 Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis
Blackwell, A. M.; Jami-Alahmadi, Y.; Nasamu, A. S.; Kudo, S.; Senoo, A.; Slam, C.; Tsumoto, K.; Wohlschlegel, J. A.; Caaveiro, J. M. M.; Goldberg, D. E.; Sigala, P. A.
10.1101/2024.05.30.596652 — biochemistry — Posted on 2024-10-13
3329 Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis
Huang, Y.-T.; Abdrabo, K. A. E.-S.; Phang, G. J.; Fan, Y.-H.; Wu, Y.-T.; Ou, J.-H.; Hulcr, J.
10.1101/2024.10.09.617500 — evolutionary biology — Posted on 2024-10-13
3332 The role of GPR87 in Pulmonary Fibrosis
Khoury, J.; Ahangari, F.; Adams, T.; Justet, A.; Manning, E.; McDonough, J. E.; Barnthaler, T.; Anderson, S.; Nikola, F.; Beermann, M. L.; Gomez, J. L.; Kaminski, N.
10.1101/2024.10.10.617569 — cell biology — Posted on 2024-10-13
3333 Comparative impact of porcine reproductive and respiratory virus and swine influenza A virus infections on respiratory lymph nodes B cells and macrophages.
Hervet, C.; Perrin, A.; Renson, P.; Deblanc, C.; Munoz, M.; Meurens, F.; Argilaguet, J.; Simon, G.; Bourry, O.; Maisonnasse, P.; Nicolas, B.
10.1101/2024.10.11.617816 — immunology — Posted on 2024-10-13
3334 Mechanism of intestinal microbial metabolic flux disorder in hypertension
Wenkai, L.; Yuchen, Z.; Meiling, W.; Shirong, L.; Qing, L.; Qi, L.; Fenglong, Y.
10.1101/2024.10.09.617349 — bioinformatics — Posted on 2024-10-13
3335 Deciphering RNA regulation with a foundation language model
Zhou, H.; Hu, Y.; Zheng, Y.; Li, J.; Peng, J.; Zhang, G.; Wang, Z.
10.1101/2024.10.12.617732 — bioinformatics — Posted on 2024-10-13
3336 Directional Immobilisation of SpyTag Bacteriophage on PDMS surfaces for Phage based Microfluidics
Liyanagedera, S. B. W.; Williams, J.; Wheatley, J. P.; Biketova, A. Y.; Sagona, A. P.; Feher, T.; Kulkarni, V.
10.1101/2024.10.11.617866 — bioengineering — Posted on 2024-10-13
3338 An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4
Bhaduri, S. E.; Braza, M. K. E.; Stanchev, S.; Bach, K.; Tauber, M.; Al-Bawab, R.; Liu, L. J.; Trujillo, D. F.; Solorio-Kirpichyan, K.; Srivastava, A.; Sanlley-Hernandez, J.; O'Donoghue, A. J.; Lemberg, M. K.; Amaro, R. E.; Strisovsky, K.; Neal, S. E.
10.1101/2024.10.13.618094 — biochemistry — Posted on 2024-10-13
3339 Identification of leaf rust resistance loci in hard winter wheat using genome-wide association mapping
Lakkakula, I. P.; Kolmer, J. A.; Sharma, R.; St. Amand, P.; Bernardo, A.; Bai, G.; Ibrahim, A.; Bowden, R. L.; Carver, B. F.; Boehm, J. D.; Aoun, M.
10.1101/2024.10.09.617432 — genomics — Posted on 2024-10-13
3340 New insights into past and future invasion of Drosophila suzukii using novel genomic resources and statistical methods to combine individual and pool sequencing data
Camus, L.; Rode, N. O.; Serga, S.; Loiseau, A.; Chen, X.; Iampietro, C.; Kenis, M.; Marande, W.; Mensch, J.; Parrinello, H.; Savic Veselinovic, M.; Valiere, S.; Zhang, J.; Boitard, S.; Gautier, M.
10.1101/2024.10.11.617812 — evolutionary biology — Posted on 2024-10-13
3341 The dinucleotide structure of NAD enables specific reduction on mineral surfaces
Pereira, D. P. H.; Xie, X.; Beyazay, T.; Paczia, N.; Subrati, Z.; Belz, J.; Volz, K.; Tueysuez, H.; Preiner, M.
10.1101/2024.10.11.617347 — evolutionary biology — Posted on 2024-10-13
3342 Suspended and sinking particle-associated microbiomesexhibit distinct lifestyles in the Elbe estuary
Tobias-Hünefeldt, S. P.; Woodhouse, J. N.; Ruscheweyh, H.-J.; Sunagawa, S.; Russnak, V.; Streit, W. R.; Grossart, H.-P.
10.1101/2024.10.09.617383 — ecology — Posted on 2024-10-13
3343 The food grade bacterium Lactobacillus helveticus VEL12193 promotes autophagy by releasing membrane vesicles
Bringer, M.-A.; Al Azzaz, J.; Buteau, B.; Proukhnitzky, L.; Aumeunier, A.; Manceau, S.; Bermudez-Humaran, L. G.; Chain, F.; Daniel, C.; Jacquin, E.; Acar, N.; Rieu, A.; Lapaquette, P.
10.1101/2024.10.13.618067 — microbiology — Posted on 2024-10-13
3344 HIV-2 evolved ZAP resistance despite increased CpG levels
Kmiec, D.; Nchioua, R.; Erdemci-Evin, S.; Lapp, S. A.; Carnathan, D.; Bosinger, S. E.; Kirchhoff, F.
10.1101/2024.10.13.618097 — microbiology — Posted on 2024-10-13
3347 X-ray Diffraction Reveals Periodicity in Murine Neocortex
Murokh, S.; Willerson, E. N.; Lazarev, A.; Lazarev, P.; Brumberg, J. C.
10.1101/2024.10.13.618071 — neuroscience — Posted on 2024-10-13
3350 Can we predict sleep health based on brain features? A large-scale machine learning study
Raimondo, F.; Bi, H.; Komeyer, V.; Kasper, J.; Primus, S. A.; Hoffstaedter, F.; Mandal, S.; Waite, L.; Winkelmann, J.; Oexle, K.; Eickhoff, S.; Tahmasian, M.; Patil, K.
10.1101/2024.10.13.618080 — neuroscience — Posted on 2024-10-13
3351 Amyloid-beta, alpha-synuclein and tau aggregated co-pathologies enhance neuropathology and neuroinflammation
Webster, J. M.; Stone, W. J.; Yang, Y.-T.; Miller, A. T.; Childers, G. M.; Corbin-Stein, N. J.; Mudium, N.; Molina, J.; Won, W.-J.; Sandoval, I. M.; Tyrrell, D. J.; Manfredsson, F. P.; Kordower, J. H.; Harms, A. S.
10.1101/2024.10.13.618101 — neuroscience — Posted on 2024-10-13
3352 Neural mechanisms of adaptive value coding in the amygdala
Hinz, J.; Mahn, M.; Mueller, S.; Szonyi, A.; Eichlisberger, T.; Luthi, A.
10.1101/2024.10.13.618086 — neuroscience — Posted on 2024-10-13
3353 Semi-automated Production of Cell-free Biosensors
Brown, D. M.; Phillips, D. A.; Garcia, D. C.; Arce, A.; Lucci, T.; Davies, J. P.; Mangini, J.; Rhea, K. A.; Bernhards, C. B.; Biondo, J. R.; Blum, S. M.; Cole, S. D.; Lee, J. A.; Lee, M. S.; McDonald, N. D.; Wang, B.; Perdue, D. L.; Thavarajah, W.; Karim, A. S.; Lux, M. W.; Jewett, M. C.; Miklos, A. E.; Lucks, J. B.
10.1101/2024.10.13.618078 — synthetic biology — Posted on 2024-10-13
3355 Impaired Suppression of Plasma Lipid Extraction and its Partitioning Away from Muscle by Insulin in Humans with Obesity
Katsanos, C. S.; Tran, L.; Hoffman, N.; Roust, L. R.; De Filippis, E. A.; Mandarino, L. J.; Johnsson, K.; Belohlavek, M.; Buras, M. R.
10.1101/2024.06.11.598550 — physiology — Posted on 2024-10-13
3357 A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer
Munoz-Erazo, L.; Park, S. M.; Lin, S.; Chen, C.-J. J.; Zhou, L. Y. Y.; Rhodes, J. L.; Jeon, T.; Fenton, S.; McCall, J. L.; Kemp, R. A.; Dunbar, R.
10.1101/2024.10.06.616904 — cancer biology — Posted on 2024-10-13
3362 Curative levels of endogenous gene replacement achieved in non-human primate liver using programmable genomic integration
Xie, J.; Dunyak, M. T.; Hanna, P.; Nan, A. X.; Estes, B.; Cochrane, J. C.; Wu, S.; Wang, J.; McGinnis, C.; Wang, Q.; Pokharel, R.; Paudel, D.; Zhang, J.; Li, D.; Amin, P.; Narayan, S.; Hsia, A.; Hazelbaker, D. Z.; Shi, X.; Packer, M.; Duke, B.; Dickerson, R.; Piard, C.; Meagher, M.; Gatlin, J.; Svenson, S.; Monsef, A.; Bourdeau, R. W.; Lam, K.; Reid, S.; Kazemian, M.; Chander, N.; Holland, R.; Heyes, J.; Mukherjee, S.; Kumar, S.; O'Connell, D. J.; Finn, J. D.
10.1101/2024.10.12.617700 — bioengineering — Posted on 2024-10-13
3363 A versatile protocol for purifying recombinant proteins from Nicotiana benthamiana for structural studies
Lawson, A. W.; Macha, A.; Neumann, U.; Gunkel, M.; Chai, J.; Behrmann, E.; Schulze-Lefert, P.
10.1101/2024.10.13.618061 — biochemistry — Posted on 2024-10-13
3365 A Suite of Foundation Models Captures the Contextual Interplay Between Codons
Naghipourfar, M.; Chen, S.; Howard, M.; Macdonald, C.; Saberi, A.; Hagen, T.; Mofrad, M.; Coyote-Maestas, W.; Goodarzi, H.
10.1101/2024.10.10.617568 — genomics — Posted on 2024-10-13
3366 High-Resolution Genome-Wide Mapping of Chromatin Accessibility and Torsional Stress
Hall, P. M.; Mayse, L. M.; Bai, L.; Smolka, M. B.; Pugh, B. F.; Wang, M. D.
10.1101/2024.10.11.617876 — genomics — Posted on 2024-10-13
3369 Public RNA-seq data are not representative of global human diversity
Gallego Romero, I.; Rodenberg, G.; Arner, A. M.; Li, L.; Beasley, I. J. A.; Rossow, R.; Ryan, N.; Wang, S.; Lea, A. J.
10.1101/2024.10.11.617967 — genomics — Posted on 2024-10-13
3370 Real-time genomic characterization of pediatric acute leukemia using adaptive sampling
Geyer, J.; Opoku, K.; Lin, J.; Ramkissoon, L.; Mullighan, C.; Bhakta, N.; Alexander, T. B.; Wang, J. R.
10.1101/2024.10.11.617690 — genomics — Posted on 2024-10-13
3371 Germline and somatic genetic effects on gene expression and outcome in patients with Multiple Myeloma
Natri, H. M.; Bui, L.; Peter, L.; Argente, B.; Federico, A.; Gutierrez, A.; Chung, M.-i.; Keats, J.; Banovich, N. E.
10.1101/2024.10.09.617438 — genomics — Posted on 2024-10-13
3372 Early establishment and life course stability of sex biases in the human brain transcriptome
Benoit-Pilven, C.; Asteljoki, J. V.; Leinonen, J.; Karjalainen, J.; Daly, M. J.; Tukiainen, T.
10.1101/2024.10.11.617734 — genomics — Posted on 2024-10-13
3373 Population genomics reveals strong impacts of genetic drift without purging and guides conservation of bull and giant kelp
Bemmels, J. B.; Starko, S.; Weigel, B. L.; Hirabayashi, K.; Pinch, A.; Elphinstone, C.; Dethier, M. N.; Rieseberg, L. H.; Page, J. E.; Neufeld, C. J.; Owens, G. L.
10.1101/2024.10.10.617648 — evolutionary biology — Posted on 2024-10-13
3374 Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene program in bat wing development
Schindler, M.; Feregrino, C.; Aldrovandi, S.; Lo, B.-W.; Monaco, A. A.; Ringel, A. R.; Morales, A.; Zehnder, T.; Behncke, R. Y.; Glaser, J.; Barclay, A.; Andrey, G.; Kragesteen, B. K.; Hagerling, R.; Haas, S. A.; Vingron, M.; Ulitsky, I.; Marti-Renom, M.; Hechavarria, J. C.; Fasel, N. J.; Hiller, M.; Lupianez, D.; Mundlos, S.; Real, F. M.
10.1101/2024.10.10.617585 — evolutionary biology — Posted on 2024-10-13
3380 SUMOylation differentially regulates SMCHD1 complex formation and function in a genomic context-specific manner
Goossens, R.; Tihaya, M. S.; Willemsen, I. M.; Straasheijm, K. R.; van der Vliet, P. J.; Gonzalez-Prieto, R.; Vertegaal, A. C. O.; Tapscott, S. J.; Balog, J.; van der Maarel, S. M.
10.1101/2024.10.13.618066 — molecular biology — Posted on 2024-10-13
3381 A noncanonical glycoprotein H complex enhances cytomegalovirus entry
Norris, M. J.; Henderson, L. A.; Siddiquey, M. N. A.; Brunel, S.; Yin, J.; Yoo, K.; Saphire, E. O.; Benedict, C. A.; Kamil, J. P.
10.1101/2024.10.13.617647 — microbiology — Posted on 2024-10-13
3383 Identification of potential inflammation markers for outgrowth of cow's milk allergy
Hendrickx, D. M.; Long, M.; PRESTO study team, ; Wopereis, H.; van der Molen, R. G.; Belzer, C.
10.1101/2024.05.24.595813 — immunology — Posted on 2024-10-13
3385 Direct and indirect RANK ligand and CD40 ligand signaling regulate the maintenance of thymic epithelial cell frequency and properties in the adult thymus
Hayama, M.; Ishii, H.; Miyauchi, M.; Yoshida, M.; Hagiwara, N.; Muramatsu, W.; Namiki, K.; Endo, R.; MIyao, T.; Akiyama, N.; Akiyama, T.
10.1101/2024.10.10.617559 — immunology — Posted on 2024-10-13
3389 The evolution of root hydraulic traits in wheat over 100 years of breeding
Baca Cabrera, J. C.; Vanderborght, J.; Boursiac, Y.; Behrend, D.; Gaiser, T.; Nguyen, T. H.; Lobet, G.
10.1101/2024.10.10.617660 — plant biology — Posted on 2024-10-13
3390 A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness
Debnath, A. J.; Harencar, L.; Kucka, M.; Kovar, M.; Ivanisova, E.; Mistrikova, V.; Gazo, J.; Razna, K.
10.1101/2024.10.10.617604 — plant biology — Posted on 2024-10-13
3392 Exploring the Pharmacological Potential of Kaurenoic Acid Produced via Synthetic Biology
Pimentel, L. L.; Teixeira, F. S.; Soares, A. M. S.; Costa, P. T.; Fontes, A. L.; Vidigal, S.; Pintado, M.; Rodriguez-Alcala, L. M.
10.1101/2024.10.10.617616 — pharmacology and toxicology — Posted on 2024-10-13
3397 Large Serine Integrase Off-Target Discovery with Deep Learning for Genome Wide Prediction
Bakalar, M. H.; Biondi, T.; Liang, X.; Santesmasses, D.; Barra, A. M.; Mehta, J. B.; Wang, J.; Hazelbaker, D. Z.; Finn, J. D.; O'Connell, D. J.
10.1101/2024.10.10.617699 — bioinformatics — Posted on 2024-10-13
3400 Rapid speciation in the holopelagic ctenophore Mnemiopsis following glacial recession
Ketchum, R. N.; Smith, E. G.; Toledo, L.; Leach, W. B.; Padillo-Anthemides, N.; Baxevanis, A. D.; Reitzel, A. M.; Ryan, J. F.
10.1101/2024.10.10.617593 — evolutionary biology — Posted on 2024-10-13
3404 Recent codon preference reversals in the Drosophila melanogaster lineage
Yamashita, H.; Matsumoto, T.; Kawashima, K.; Daanaa, H. S. A.; Yang, Z.; Akashi, H.
10.1101/2024.10.10.617326 — evolutionary biology — Posted on 2024-10-13
3405 MMP21 behaves as a fluid flow transported morphogen to impart laterality during development
Ott, T.; Brugger, A.; Szenker-Ravi, E.; Kurrle, Y.; Aberle, O.; Tisler, M.; Blum, M.; Whalen, S.; Bouvagnet, P.; Reversade, B.; Schweickert, A.
10.1101/2024.10.13.618030 — developmental biology — Posted on 2024-10-13
3406 A diverse population of pericoerulear neurons controls arousal and exploratory behaviors
Luskin, A. T.; Li, L.; Fu, X.; Martin, M. M.; Barcomb, K.; Girven, K. S.; Blackburn, T.; Wells, B. A.; Thai, S. T.; Li, E. M.; Rana, A. N.; Simon, R. C.; Sun, L.; Gao, L.; Murry, A. D.; Golden, S. A.; Stuber, G. D.; Ford, C. P.; Gu, L.; Bruchas, M. R.
10.1101/2022.06.30.498327 — neuroscience — Posted on 2024-10-13
3408 Humans actively reconfigure neural task states
Ritz, H.; Jha, A.; Pillow, J. W.; Daw, N. D.; Cohen, J. D.
10.1101/2024.09.29.615736 — neuroscience — Posted on 2024-10-13
3411 Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content
Eskelinen, A. S. A.; Kosonen, J. P.; Hamada, M.; Esrafilian, A.; Florea, C.; Grodzinsky, A. J.; Tanska, P.; Korhonen, R. K.
10.1101/2024.10.08.617186 — bioengineering — Posted on 2024-10-13
3412 Dissecting Regulatory Non-Coding Heart Disease GWAS Loci with High-Resolution 3D Chromatin Interactions Reveals Causal Genes with Pathophysiological Relevance to Heart Failure
Gill, R.; Lu, D.; Eres, I.; Lu, J.; Cui, J.; Yu, Z. J.; Yamawaki, T.; Zhou, H.; Pei, B.; Amrute, J.; Ang, Y.-s.; Wang, S.; Lavine, K.; Ason, B.; Li, C.-M. K.; Hsu, Y.-H.
10.1101/2024.10.08.617295 — genomics — Posted on 2024-10-13
3413 Medieval genomes from eastern Iberia illuminate the role of Morisco mass deportations in dismantling a long-standing genetic bridge with North Africa
Oteo-Garcia, G.; Silva, M.; Foody, M. G. B.; Yau, B.; Fichera, A.; Alapont, L.; Justeau, P.; Rodrigues, S.; Monteiro, R.; Gandini, F.; Rovira, M.; Ribera i Lacomba, A.; Beneyto, J. P.; Mattiangeli, V.; Bradley, D. G.; Edwards, C. J.; Pala, M.; Richards, M. B.
10.1101/2024.10.09.617385 — evolutionary biology — Posted on 2024-10-13
3418 NK cells mediate preventive efficacy of intravenous BCG against lung metastasis in mice
Guerrero, C.; Moreo, E.; Araujo-Voces, M.; Uranga, S.; Gomez, A. B.; Martin, C.; Aguilo, N.
10.1101/2024.10.09.617367 — immunology — Posted on 2024-10-13
3419 Inferring post-transcriptional regulation within and across cell types in human testis
Khan, S.; Elcheikhali, M.; Leduc, A.; Huffman, R. G.; Derks, J.; Franks, A.; Slavov, N.
10.1101/2024.10.08.617313 — systems biology — Posted on 2024-10-13
3421 Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification
Lam, L. P. Y.; Yamamoto, S.; Afifi, O. A.; Ji, P.; Osakabe, Y.; Osakabe, K.; Umezawa, T.; Tobimatsu, Y.
10.1101/2024.10.08.617307 — plant biology — Posted on 2024-10-13
3423 Decoding Spatial Tissue Architecture: A Scalable Bayesian Topic Model for Multiplexed Imaging Analysis
Peng, X.; Smithy, J. W.; Yosofvand, M.; Kostrzewa, C. E.; Bleile, M.; Ehrich, F. D.; Lee, J.; Postow, M. A.; Callahan, M. K.; Panageas, K. S.; Shen, R.
10.1101/2024.10.08.617293 — bioinformatics — Posted on 2024-10-13
3426 Nerve-associated macrophages control adipose homeostasis across lifespan and restrain age-related inflammation
Gonzalez-Hurtado, E.; Leveau, C.; Li, K.; Qu, R.; Mishra, M.; Goldberg, E. L.; Sidorov, S.; Yeung, S. T.; Khairallah, C.; Gonzalez, D.; Shepard, T. M.; Camell, C.; Artyomov, M. N.; Kluger, Y.; Khanna, K. M.; Dixit, V. D.
10.1101/2024.10.12.618004 — immunology — Posted on 2024-10-13
3427 Nutritional state-dependent modulation of Insulin-Producing Cells in Drosophila
Singh Bisen, R.; Iqbal, F. M.; Cascino-Milani, F.; Bockemühl, T.; Ache, J. M.
10.1101/2024.04.24.590939 — neuroscience — Posted on 2024-10-13
3429 Catabolism of extracellular glutathione supplies amino acids to support tumor growth
Hecht, F.; Zocchi, M.; Tuttle, E. T.; Ward, N. P.; Smith, B.; Kang, Y. P.; Cazarin, J.; Soares, Z. G.; Ozgurses, M. E.; Zhao, H.; Sheehan, C.; Alimohammadi, F.; Munger, L. D.; Trivedi, D.; Asantewaa, G.; Blick-Nitko, S. K.; Zoeller, J. J.; Chen, Y.; Vasiliou, V.; Turner, B. M.; Muir, A.; Coloff, J. L.; Munger, J.; DeNicola, G. M.; Harris, I. S.
10.1101/2024.10.10.617667 — cancer biology — Posted on 2024-10-13
3431 Synergistic Role of Amino Acids in Enhancing mTOR Activation Through Lysosome Positioning
Kolaczkowski, O. M.; Goodson, B. A.; Montenegro Vazquez, V.; Jia, j.; Qadir Bhat, A.; Kim, T.-H.; Pu, J.
10.1101/2024.10.12.618047 — cell biology — Posted on 2024-10-13
3433 Load activated FGFR and beta1 integrins target distinct chondrocyte mechano-response genes
Dietmar, H. F.; Weidmann, P. A.; Alberton, P.; Teichwart, T.; Renkawitz, T.; Vortkamp, A.; Aszodi, A.; Richter, W.; Diederichs, S.
10.1101/2024.10.11.617817 — cell biology — Posted on 2024-10-13
3434 miR126-mediated impaired vascular integrity in Rett syndrome
Osaki, T.; Wan, Z.; Haratani, K.; Jin, Y.; Campisi, M.; Barbie, D. A.; Kamm, R. D.; Sur, M.
10.1101/2024.10.11.617929 — cell biology — Posted on 2024-10-13
3435 Protective effects of PDGF-AB/BB against cellular senescence in human intervertebral disc
Zhang, C.; Diaz-Hernandez, M. E.; Fukunaga, T.; Shenoy, S.; Yoon, S. T.; Haglund, L.; Drissi, H.
10.1101/2024.10.11.617862 — cell biology — Posted on 2024-10-13
3438 mRNA-based influenza vaccine expands breadth of B cell response in humans
Matz, H. C.; Yu, T.-G.; Zhou, J. Q.; Peyton, L.; Madsen, A.; Han, F.; Schmitz, A. J.; Horvath, S. C.; Dixit, K.; Keplinger, H. K.; Strnad, B. S.; Hoegger, M. J.; Middleton, W. D.; Klebert, M. K.; Lin, N. H.; Nachbagauer, R.; Paris, R.; Turner, J. S.; Presti, R. M.; Lee, J.; Ellebedy, A.
10.1101/2024.10.10.617255 — immunology — Posted on 2024-10-13
3439 RNA Polymerase II is a Polar Roadblock to a Progressing DNA Fork
Kay, T. M.; Inman, J. T.; Lubkowska, L.; Le, T. T.; Qian, J.; Hall, P. M.; Wang, D.; Kashlev, M.; Wang, M. D.
10.1101/2024.10.11.617674 — biophysics — Posted on 2024-10-13
3440 Telocyte networks are an essential stem cell niche component in hair follicle regeneration
Canella, M.; Nalick, S.; Gharbi, A.; Jamous, A.; Corem, N.; Ben-Porath, I.; Hofree, M.; Shoshkes Carmel, M.
10.1101/2023.05.17.541070 — cell biology — Posted on 2024-10-13
3442 Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage
Murley, A.; Popovici, A.; Hu, X. S.; Lund, A.; Wickham, K.; Durieux, J.; Joe, L.; Koronyo, E.; Dillin, A.
10.1101/2024.10.11.617892 — cell biology — Posted on 2024-10-13
3448 Dissecting the nutritional regulations of a whole amino acid transporter family from a complex genome species: A holistic approach turning weaknesses into strengths
Le Garrec, S.; Pinel, K.; Heraud, C.; Ganot, A.; Veron, V.; Morin, G.; Iorfida, O.; Cardona, E.; Marandel, L.; Devin, A.; Labonne, J.; Averous, J.; Bruhat, A.; Seiliez, I.; BEAUMATIN, F.
10.1101/2024.10.11.617833 — cell biology — Posted on 2024-10-13
3449 Syngeneic adipose-derived stromal cells modulate the immune response but have limited persistence within decellularized adipose tissue implants in C57BL/6 mice
Walker, J. T.; Cooper, T. T.; Dunmore-Buyze, J.; Serack, F. E.; Brooks, C.; Grant, A.; Drangova, M.; Lajoie, G.; Dekaban, G. A.; Flynn, L. E.
10.1101/2024.10.11.617847 — cell biology — Posted on 2024-10-13
3451 Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation
Dahmane, S.; Schexnaydre, E.; Zhang, J.; Rosendal, E.; Chotiwan, N.; Kumari Singh, B.; Yau, W.-L.; Lundmark, R.; Barad, B.; Grotjahn, D. A.; Liese, S.; Carlson, A.; Overby, A.; Carlson, L.-A.
10.1101/2024.10.13.618056 — microbiology — Posted on 2024-10-13
3452 Integration of distinct cortical inputs to primary and higher order inhibitory cells of the thalamus
Puzzo, C. D.; Martinez-Garcia, R. I.; Liu, H.; Dyson, L. F.; Gilbert, W. O.; Cruikshank, S. J.
10.1101/2024.10.12.618039 — neuroscience — Posted on 2024-10-13
3455 Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells
Maltsev, A. V.; Subirachs, V. V.; Monfredi, O.; Juhaszova, M.; Warrier, P. A.; Rakshit, S.; Tagirova, S.; Maltsev, A. V.; Stern, M. D.; Lakatta, E. G.; Maltsev, V. A.
10.1101/2024.10.09.617454 — biophysics — Posted on 2024-10-13
3464 Data-Driven Equation-Free Dynamics Applied to Many-Protein Complexes: The Microtubule Tip Relaxation
Wu, J.; Dasetty, S.; Beckett, D.; Wang, Y.; Xue, W.; Skora, T.; Bidone, T. C.; Ferguson, A. L.; Voth, G. A.
10.1101/2024.10.10.617682 — biophysics — Posted on 2024-10-13
3465 ExoSloNano: Multi-Modal Nanogold Tags for identi-fication of Macromolecules in Live Cells & Cryo-Electron Tomograms
Young, L. N.; Sherrard, A.; Zhou, H.; Shaikh, F.; Hutchings, J.; Riggi, M.; Rosen, M. K.; Giraldez, A.; Villa, E.
10.1101/2024.10.12.617288 — biophysics — Posted on 2024-10-13
3468 The invasion pore induced by Toxoplasma gondii
Kegawa, Y.; Male, F.; Jimenez Munguia, I.; Blank, P. S.; Mekhedov, E.; Ward, G.; Zimmerberg, J.
10.1101/2024.10.11.617945 — biophysics — Posted on 2024-10-13
3472 DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation
Moreno, N. C.; Korchak, E. J.; Latancia, M. T.; D'Orlando, D. A.; Adegbenro, T.; Bezsonova, I.; Woodgate, R.; Ashton, N. W.
10.1101/2024.10.12.618026 — biochemistry — Posted on 2024-10-13
3475 Potent Anti-Influenza Synergistic Activity of Theobromine and Arainosine
Lahiri, H.; Israeli, E.; Krugliak, M.; Britan-Rosich, Y.; Ravins, T.; Arkin, I. T.
10.1101/2024.10.13.618054 — microbiology — Posted on 2024-10-13
3476 Humans actively reconfigure neural task states
Ritz, H.; Jha, A.; Pillow, J. W.; Daw, N. D.; Cohen, J. D.
10.1101/2024.09.29.615736 — neuroscience — Posted on 2024-10-13
3478 A theoretical basis for cell death
Himeoka, Y.; Horiguchi, S. A.; Kobayashi, T. J.
10.1101/2024.03.04.583348 — systems biology — Posted on 2024-10-13
3479 Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer
Cross, W.; Nowinski, S.; Cresswell, G.; Mossner, M.; Banerjee, A.; Lu, B.; Williams, M.; Vlachogiannis, G.; Gay, L.; Baker, A.-M.; Kimberley, C.; Whiting, F.; Belnoue-Davis, H.; Martinez, P.; Traki, M.; Walther, V.; Smith, K.; Fernandez-Mateos, J.; Yara, E.; Oliveira, E.; Milite, S.; Caravagna, G.; James, C.; Elia, G.; Berner, A. M.; Choi, R. C.; Ramagiri, P.; Chauhan, R.; Matthews, N.; Murphy, J.; Antoniou, A.; Clark, S.; Mitchison, M.; Aleong, J.-A. C.; Domingo, E.; Spiteri, I. S.; McDonald, S.; Shibata, D.; Lacle, M. M.; Wang, L. M.; Moorghen, M.; Tomlinson, I.; Novelli, M.; Jansen, M.; Wat
10.1101/2020.03.26.007138 — cancer biology — Posted on 2024-10-13
3480 Active RNA synthesis patterns nuclear condensates
Banani, S. F.; Goychuk, A.; Natarajan, P.; Zheng, M. M.; Dall'Agnese, G.; Henninger, J. E.; Kardar, M.; Young, R. A.; Chakraborty, A. K.
10.1101/2024.10.12.614958 — biophysics — Posted on 2024-10-13
3481 Data-Driven Image Analysis to Determine Antibody-Induced Dissociation of Cell-Cell Adhesion and Antibody Pathogenicity in Pemphigus Vulgaris
Moghaddam, A. O.; Jin, X.; Zhai, H.; Safa, B. T.; Seiffert-Sinha, K.; Leiker, M.; Rosenbohm, J.; Meng, F.; Sinha, A. A.; Yang, R.
10.1101/2024.10.09.617446 — biophysics — Posted on 2024-10-13
3482 Autophagy across tissues of aging mice
Carosi, J. M.; Martin, A.; Hein, L. K.; Hassiotis, S.; Hattersley, K. J.; Turner, B. J.; Fourrier, C.; Bensalem, J.; Sargeant, T. J.
10.1101/2024.09.11.612427 — cell biology — Posted on 2024-10-13
3484 Neuro-GSTH: A Geometric Scattering and Persistent Homology Framework for Uncovering Spatiotemporal Signatures in Neural Activity
Bhaskar, D.; Moore, J. L.; Zhang, Y.; Gao, F.; Rieck, B.; Wolf, G.; Pushkarskaya, H.; Khasawneh, F.; Munch, E.; Greco, V.; Pittenger, C.; Krishnaswamy, S.
10.1101/2023.03.22.533807 — bioinformatics — Posted on 2024-10-13
3485 Effects of parental care on skin microbial community composition in poison frogs
Fischer, M.-T.; Xue, K. S.; Costello, E. K.; Dvorak, M.; Robaczewska, A.; Raboisson, G.; Caty, S. N.; Relman, D. A.; O'Connell, L. A.
10.1101/2024.09.11.612488 — microbiology — Posted on 2024-10-13
3486 Short-Term Evolution and Dispersal Patterns of fluconazole-resistance in Candida auris clade III
Cancino-Munoz, I.; Mulet-Bayona, J. V.; Salvador-Garcia, C.; Tormo-Palop, N.; Guna, R.; Gimeno, C.; Gonzalez-Candelas, F.
10.1101/2024.05.22.595305 — microbiology — Posted on 2024-10-13
3488 Brain Pretargeted PET; New Horizons to Image CNS Targets with Monoclonal Antibodies
Gustavsson, T.; Kustermann, T.; Hvass, L.; Shalgunov, V.; Clausen, A. S.; Stotz, S.; Wuensche, T. E.; Knudsen, G. M.; Aldana, B. I.; Niewoehner, J.; Gobbi, L.; Honer, M.; Battisti, U. M.; Kjaer, A.; Herth, M. M.
10.1101/2024.10.12.617694 — neuroscience — Posted on 2024-10-13
3490 Cryo-EM visualizes multiple steps of dynein activation pathway
Kendrick, A.; Nguyen, K.; MA, W.; Karasmanis, E.; Amaro, R. E.; Reck-Peterson, S.; Leschziner, A.
10.1101/2024.09.28.615567 — biophysics — Posted on 2024-10-13
3495 Reducing spatial heterogeneity in coverage improves the effectiveness of dog vaccination against rabies
Ferguson, E.; Lugelo, A.; Czupryna, A.; Anderson, D.; Lankester, F.; Sikana, L.; Dushoff, J.; Hampson, K.
10.1101/2024.10.03.616420 — ecology — Posted on 2024-10-13
3496 Neocortical differentiation and hippocampal integration of non-meaningful items and their spatial location
Nemecz, Z.; Homolya, I.; Ilyes, A.; Mezö, G.; Kis, H.; Varga, V. A.; Werkle-Bergner, M.; Keresztes, A.
10.1101/2024.10.09.617494 — neuroscience — Posted on 2024-10-12
3499 Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration
Nascimento, F.; Ozyurt, M. G.; Halablab, K.; Bhumbra, G. S.; Caron, G.; Baczyk, M.; Zytnicki, D.; Manuel, M.; Roselli, F.; Brownstone, R. M.; Beato, M.
10.1101/2024.04.10.588918 — neuroscience — Posted on 2024-10-12
3501 Allele-specific silencing of a dominant SETX mutation in familial amyotrophic lateral sclerosis type 4
Winkelsas, A.; Apfel, A.; Johnson, B.; Harmison, G.; Li, D.; Cheung, V.; Grunseich, C.
10.1101/2024.10.11.617871 — genetics — Posted on 2024-10-12
3504 Reshaping the tumor microenvironment by degrading glycoimmune checkpoints Siglec-7 and -9
Wang, C.; Hou, Y.; Zak, J.; Zheng, Q.; McCord, K. A.; Wu, M.; Zhang, D.; Chung, S.; Shi, Y.; Ye, J.; Zhao, Y.; Hajjar, S.; Wilson, I. A.; Paulson, J. C.; Teijaro, J. R.; Zhou, X.; Sharpless, B. K.; Macauley, M. S.; Wu, P.
10.1101/2024.10.11.617879 — immunology — Posted on 2024-10-12
3505 Integrated scFv identification and CAR T cell generation for AML targeting in vivo
Müller-Tidow, C.; Liu, Y.; Lauk, A.; Sedloev, D.; Brysting, J.; Cetin, E.; Liu, C.; Moennig, M.; Luft, T.; Yun, H.; Schmitt, M.; Sauer, T.; Zhou, F.; Rohde, C.
10.1101/2024.10.08.617189 — immunology — Posted on 2024-10-12
3506 RIPK2 is crucial for the microglial inflammatory response to bacterial muramyl dipeptide but not to lipopolysaccharide
Yang, C.; Machado da Silva, M. C.; Howell, J. A.; Larochelle, J.; Liu, L.; Gunraj, R. E.; Pinheiro de Oliveira, A.; Candelario-Jalil, E.
10.1101/2024.10.09.617444 — neuroscience — Posted on 2024-10-12
3507 Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats
Christiansen, J. R.; Ferreira, S. A.; Szymkowski, D. E.; Jakobsson, J.; Tansey, M. G.; Romero-Ramos, M.
10.1101/2024.10.11.617361 — neuroscience — Posted on 2024-10-12
3509 Human BNST volume is not simply sexually dimorphic
Berry, S. C.; Suri, H. K.; Lisi, M.; Aggleton, J. P.; Hodgetts, C. J.
10.1101/2024.10.09.617217 — neuroscience — Posted on 2024-10-12
3513 A multi-omics and cell type-specific characterization of the ventral striatum in human cocaine use disorder
Zillich, E.; Artioli, A.; Rossetti, A. C.; Avetyan, D.; Belschner, H.; Frank, J.; Stein, F.; Schwarz, J. J.; Mechawar, N.; Turecki, G.; Noethen, M. M.; Hansson, A. C.; Witt, C. C.; Rietschel, M.; Koch, P.; Spanagel, R.; Zillich, L.; Witt, S. H.
10.1101/2024.10.09.617337 — neuroscience — Posted on 2024-10-12
3514 Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins After Early Life Seizures
Khalife, M. R.; Villarin, C.; Ruiz, J. M.; McClelland, S. A.; Rabbo, K. A.; Mahoney, J. M.; Scott, R. C.; Hernan, A. E.
10.1101/2024.10.09.617457 — neuroscience — Posted on 2024-10-12
3517 Optical coherence tomography enables longitudinal evaluation of cell graft-directed remodeling in stroke lesions
Adewumi, H. O.; Simkulet, M. G.; Kureli, G.; Giblin, J. T.; Lopez, A. B.; Erdener, S. E.; Jiang, J.; Boas, D. A.; O'Shea, T. M.
10.1101/2024.10.09.617387 — neuroscience — Posted on 2024-10-12
3519 Integration of spatial transcriptomics with immunofluorescence staining reveals spatial heterogeneity and plasticity of astrocytes in experimental glioblastomas
Ghosh, M.; Pilanc-Kuldek, P.; Jacek, K.; Baluszek, S.; Poleszak, K.; Szadkowska, P.; Gielniewski, B.; Ellert-Miklaszewska, A.; Kaminska, B.
10.1101/2024.10.11.617740 — neuroscience — Posted on 2024-10-12
3521 Predicting and phase targeting brain oscillations in real-time
Jongejan, S. L.; van der Heijden, C.; Patriota, J.; Talamini, L. M.
10.1101/2024.10.12.617974 — neuroscience — Posted on 2024-10-12
3526 Astrocyte regional specialization is shaped by postnatal development
Schroeder, M. E.; McCormack, D. M.; Metzner, L.; Kang, J.; Li, K. X.; Yu, E.; Levandowski, K. M.; Zaniewski, H.; Zhang, Q.; Boyden, E.; Krienen, F. M.; Feng, G.
10.1101/2024.10.11.617802 — neuroscience — Posted on 2024-10-12
3528 Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder
Aryal, S.; Geng, C.; Kwon, M. J.; Farsi, Z.; Goble, N.; Asan, A. S.; Brenner, K.; Shepard, N.; Seidel, O.; Wang, Y.; Nicolella, A.; Song, B. J.; Keshishian, H.; Carr, S. A.; Pan, J. Q.; Sheng, M.
10.1101/2024.10.10.617460 — neuroscience — Posted on 2024-10-12
3530 Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission
White, K. I.; Khan, Y. A.; Qiu, K.; Balaji, A.; Couoh-Cardel, S.; Esquivies, L.; Pfuetzner, R. A.; Diao, J.; Brunger, A. T.
10.1101/2024.10.11.617886 — neuroscience — Posted on 2024-10-12
3531 Neuroanatomy of the Accessory Olfactory Bulb in the Fossorial Water Vole
Ruiz-Rubio, S.; Ortiz-Leal, I.; Torres, M. V.; Elsayed, M. G. A.; Somoano, A.; Sanchez-Quinteiro, P.
10.1101/2024.10.11.617790 — neuroscience — Posted on 2024-10-12
3533 Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants
Thirumalai, A.; Henseler, J.; Enayati, M.; Kusch, K.; Hessler, R.; Moser, T.; Huet, A. T.
10.1101/2024.10.12.617982 — neuroscience — Posted on 2024-10-12
3534 Dnajc3 (HSP40) Modulates Axon Regeneration in the Mouse Optic Nerve
Wang, J.; Li, Y.; Struebing, F. L.; Jardines, S.; Lin, S.-T.; Lin, F.; Geisert, E. E.
10.1101/2024.10.08.617251 — neuroscience — Posted on 2024-10-12
3535 A preserved neural code for temporal order between memory formation and recall in the human medial temporal lobe
Khazali, M. F.; Brandt, A.; Reinacher, P. C.; Kahana, M. J.; Jacobs, J.; Schulze-Bonhage, A.; Kunz, L.
10.1101/2024.10.12.618011 — neuroscience — Posted on 2024-10-12
3536 Spinal cerebrospinal fluid contacting neurons are a conserved sensory neuronal population along the mouse spinal cord
CROZAT, E.; BLASCO, E.; RAMIREZ-FRANCO, J.; RIONDEL, P.; JURCIC, N.; SEDDIK, R.; MICHELLE, C.; TROUSLARD, J.; WANAVERBECQ, N.
10.1101/2024.10.10.617653 — neuroscience — Posted on 2024-10-12
3540 Prefrontal representations of retrospective spatial working memory in a rodent radial maze task
Taliaferro, J. P.; Posani, L.; Greenwald, J.; Lim, S.; McGowan, J. C.; Pekarskaya, E.; Lacefield, C.; Fusi, S.; Kellendonk, C.
10.1101/2024.10.10.617655 — animal behavior and cognition — Posted on 2024-10-12
3542 Genomic prediction in insects: a case study on wing morphology traits in the jewel wasp Nasonia vitripennis
Xia, S.; Bukovinszkine Kiss, G.; Megens, H.-J.; Groenen, M.; Zwaan, B.; Bijma, P.; Pannebakker, B. A.
10.1101/2024.10.09.617398 — genetics — Posted on 2024-10-12
3543 Overcoming ploidy barriers: the role of triploid bridges in the genetic introgression of Cardamine amara
Bartolic, P.; Voltrova, A.; Mackova, L.; Sramkova, G.; Slenker, M.; Mandakova, T.; Garcia, N. P.; Marhold, K.; Kolar, F.
10.1101/2024.10.08.617200 — evolutionary biology — Posted on 2024-10-12
3544 Identification of a specialized lipid barrier for Drosophila metamorphosis
Lampe, L.; Newell, C. L.; Wang, B.-J.; Makki, R.; Alexandre, C.; Gilmore, I. S.; Zhao, L.; Gould, A. P.
10.1101/2024.10.11.617838 — developmental biology — Posted on 2024-10-12
3545 CellMet: Extracting 3D shape metrics from cells and tissues
Theis, S.; Mendieta-Serrano, M. A.; Chapa-Y-Lazo, B.; Chen, J.; Saunders, T. E.
10.1101/2024.10.11.617843 — developmental biology — Posted on 2024-10-12
3547 CRISPR/Cas9-based somatic knock-in of reporters in the avian embryo in ovo
Petit-Vargas, A.; Mida, B.; Goiame, R.; Alegria-Prevot, O.; Djelic, B.; Fischer, E.; Tozer, S.; Gros, J.; Manceau, M.; Morin, X.
10.1101/2024.10.10.617291 — developmental biology — Posted on 2024-10-12
3548 STAT3 signalling enhances tissue expansion during postimplantation mouse development
Nichols, J.; Azami, T.; Theeuwes, B.; Ton, M.-L. N.; Mansfield, W.; Harland, L.; Kinoshita, M.; Gottgens, B.
10.1101/2024.10.11.617785 — developmental biology — Posted on 2024-10-12
3549 Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis
Deng, Q.; Cai, P.; Luo, Y.; Zhang, Z.; Ma, W.; Huang, Z.; Chen, X.; Hao, S.; Xu, J.; Cheng, M.; Lin, X.; Zhou, R.; Duan, S.; Chen, J.; Li, R.; Shi, X.; Liu, C.; Gao, P.; Li, J.; Xie, J.; Liu, L.; Yuan, Y.; Liu, C.
10.1101/2024.10.11.617797 — developmental biology — Posted on 2024-10-12
3551 Characterization of neural infection by Oropouche orthobunyavirus
Connors, K. A.; Pedlow, M. R.; Frey, Z. D.; McGaughey, J. J.; Amarasinghe, G. K.; Duprex, W. P.; D'Aiuto, L.; Wills, Z. P.; Hartman, A. L.
10.1101/2024.10.11.617875 — microbiology — Posted on 2024-10-12
3553 Amplification of olfactory transduction currents implements sparse stimulus encoding
Belonio, K. C.; Haile, E. S.; Fyke, Z.; Vivona, L.; Konanur, V.; Zak, J. D.
10.1101/2024.10.11.617893 — neuroscience — Posted on 2024-10-12
3554 RiboTag RNA Sequencing Identifies Local Translation of HSP70 In Astrocyte Endfeet After Cerebral Ischemia
Shim, B.; Ciryam, P.; Tosun, C.; Serra, R.; Tsymbalyuk, N.; Keledjian, K.; Gerzanich, V.; Simard, J. M.
10.1101/2024.10.08.617236 — neuroscience — Posted on 2024-10-12
3555 Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in Sp4 mutant mice, a genetic model of schizophrenia and bipolar disorder
Kwon, M. J.; Perzel Mandell, K. A.; Aryal, S.; Geng, C.; Nicolella, A. A.; Valle-Tojeiro, A.; Natarajan, S.; Misri, D.; Hall, A.; Song, B. J.; Farsi, Z.; Keshishian, H.; Carr, S. A.; Sheng, M.
10.1101/2024.10.12.618006 — neuroscience — Posted on 2024-10-12
3556 Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injury
Barbay, T.; Pecchi, E.; Ramirez Franco, J. J.; Ivanov, A.; Brocard, F.; Rouach, N.; BOS, R.
10.1101/2024.10.11.617793 — neuroscience — Posted on 2024-10-12
3557 Genetic reduction of the translational repressors FMRP and 4E-BP2 preserves memory in mouse models of Alzheimer's disease
Campos Ribeiro, F.; Cozachenco, D.; Lacaille, J.-C.; Nader, K.; De Felice, F. G.; Lourenco, M. V.; Aguilar-Valles, A.; Sonenberg, N.; Ferreira, S. T.
10.1101/2024.10.08.617315 — neuroscience — Posted on 2024-10-12
3558 Thermoceptive predictions and prediction errors in the anterior insula
Toussaint, B.; Heinzle, J.; Friedli, N.; Zahnd, N. J.; Federici, E.; Koechli, L.; Harrison, O. K.; Iglesias, S.; Stephan, K. E.
10.1101/2024.10.11.617819 — neuroscience — Posted on 2024-10-12
3559 Regional associations of sleep architecture and Alzheimer's disease pathology
Buchal, A.; Elmenhorst, D.; Doering, E.; Dzialas, V.; Giehl, K.; Bischof, G.; van Eimeren, T.; Drzezga, A.; Hoenig, M.; for the T-POT study group,
10.1101/2024.10.10.617528 — neuroscience — Posted on 2024-10-12
3560 Region-specific spreading depolarization drives aberrant post-ictal behavior
Mitlasoczki, B.; Gomez, A. G.; Kamali, M.; Babushkina, N.; Baues, M.; Kück, L.; Haubrich, A. N.; Tamiolakis, T.; Breuer, A.; Granak, S.; Schwering-Sohnrey, M.; Gerhauser, I.; Baumgärtner, W.; Ewell, L.; Opitz, T.; Pitsch, J.; Musall, S.; Surges, R.; Mormann, F.; Beck, H.; Wenzel, M.
10.1101/2024.10.12.618012 — neuroscience — Posted on 2024-10-12
3564 Beyond the CTCT: Remote Structural Changes After VIM-MRgFUS in Essential Tremor
Krauss, J.; Upadhyay, N.; Purrer, V.; Borger, V.; Daamen, M.; Maurer, A.; Schmeel, C.; Radbruch, A.; Wuellner, U.; Boecker, H.
10.1101/2024.10.08.617157 — neuroscience — Posted on 2024-10-12
3565 Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis
Nilsson, I.; Su, E. J.; Fredriksson, L.; Heller Sahlgren, B.; Bagoly, Z.; Moessinger, C.; Stefanitsch, C.; Ning, F. C.; Zeitelhofer, M.; Muhl, L.; Lawrence, A.-L. E.; Scotney, P. D.; Lu, L.; Samen, E.; Ho, H.; Keep, R. F.; Medcalf, R. L.; Lawrence, D. A.; Eriksson, U.
10.1101/2024.10.11.617532 — neuroscience — Posted on 2024-10-12
3571 Brain Pretargeted PET - New Horizons to Image CNS Targets with Monoclonal Antibodies
Gustavsson, T.; Kustermann, T.; Hvass, L.; Shalgunov, V.; Clausen, A. S.; Stotz, S.; Wuensche, T. E.; Knudsen, G. M.; Aldana, B. I.; Niewoehner, J.; Gobbi, L.; Honer, M.; Battisti, U. M.; Kjaer, A.; Herth, M. M.
10.1101/2024.10.12.617694 — neuroscience — Posted on 2024-10-12
3572 Light modulates glucose and lipid homeostasis via the sympathetic nervous system
Chen, X.; Lin, E.; Haghighatian, M.; Shepard, L. W.; Hattar, S.; Kuruvilla, R.; Zhao, H.
10.1101/2024.10.11.617839 — neuroscience — Posted on 2024-10-12
3575 Food intake enhances hippocampal sharp wave-ripples
Kaya, E.; Wegienka, E.; Akhtarzandi-Das, A.; Do, H.; Eban-Rothschild, A.; Rothschild, G.
10.1101/2024.10.08.617304 — neuroscience — Posted on 2024-10-12
3576 The Growing Little Brain: Cerebellar Functional Development from Cradle to School
Lyu, W.; Thung, K.-H.; Huynh, K. M.; Wang, L.; Lin, W.; Ahmad, S.; Yap, P.-T.
10.1101/2024.10.12.617938 — neuroscience — Posted on 2024-10-12
3577 Changes in cortical grasp-related activity before and after object contact
Yan, Y.; Sobinov, A. R.; Goodman, J. M.; Okorokova, E. V.; Miller, L. E.; Bensmaia, S. J.
10.1101/2024.10.11.617909 — neuroscience — Posted on 2024-10-12
3582 Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia
Twedell, E. L.; Bair-Marshall, C. J.; Girasole, A. E.; Scaria, L. K.; Sridhar, S.; Nelson, A. B.
10.1101/2024.10.11.617939 — neuroscience — Posted on 2024-10-12
3583 A Small-molecule Antagonist Radiotracer for Positron Emission Tomography Imaging of the Mu Opioid Receptor.
Plakas, K.; Hsieh, C.-J.; Guarino, D. S.; Hou, C.; Chia, W.-K.; Young, A.; Schmitz, A.; Ho, Y.-P.; Weng, C.-C.; Lee, H.; Li, S.; Graham, T. J. A.; Mach, R. H.
10.1101/2024.10.12.618019 — neuroscience — Posted on 2024-10-12
3584 Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)
de Bakker, D. E. M.; Mihaljevic, M.; Gharat, K.; Richter, J.; van Bebber, F.; Adam, L.; Shamim-Schulze, F.; Ohlenschlaeger, O.; Bens, M.; Cirri, E.; Antebi, A.; Matic, I.; Schneider, A.; Schmid, B.; Kirstein, J.; Valenzano, D. R.
10.1101/2024.10.11.617841 — neuroscience — Posted on 2024-10-12
3585 Thalamo-frontal connectivity patterns in Tourette Syndrome: Insights from combined intracranial DBS and EEG recordings
Wehmeyer, L.; Baldermann, J. C.; Pogosyan, A.; Rodriguez Plazas, F.; Loehrer, P. A.; Bonetti, L.; Yassine, S.; Zur Muehlen, K.; Schueller, T.; Kuhn, J.; Visser-Vandewalle, V.; Tan, H.; Andrade, P.
10.1101/2024.10.09.617413 — neuroscience — Posted on 2024-10-12
3588 Neuronal correlates of sleep in honey bees
Moguilner, S.; Tiraboschi, E.; Fantoni, G.; Strelevitz, H.; Soleimani, H.; Del Torre, L.; Hasson, U.; Haase, A.
10.1101/2024.10.11.617548 — neuroscience — Posted on 2024-10-12
3591 TENM4 is an essential transduction component for touch and pain
Khallaf, M.; Huang, A. T.-L.; Dalmasso, L.; Chakrabarti, S.; Groeneveld, R.; Sierra, Y. A. B.; Garcia Contreras, J. A.; Schuetz, A.; Begay, V.; Hedtrich, S.; Zhong, W.; Popp, O.; Mertins, P.; Lewin, G. R.
10.1101/2024.10.10.617546 — neuroscience — Posted on 2024-10-12
3594 Early disruption of entorhinal dopamine in a knock-in model of Alzheimer's disease
Nakagawa, T.; Xie, J. L.; Savadkohighodjanaki, M.; Zhang, Y. J.; Jun, H.; Cao, K.; Ichii, A.; Lee, J.; Soma, S.; Medhat, Y.; Saido, T. C.; Igarashi, K. M.
10.1101/2024.10.10.617678 — neuroscience — Posted on 2024-10-12
3596 Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy
Mora, N.; Slot, E. F. J.; Lewandowski, V.; Menafra, M. P.; Sijlmans, C.; van Bakel, N.; Ignatova, Z.; Storkebaum, E.
10.1101/2024.10.11.617948 — neuroscience — Posted on 2024-10-12
3597 Simultaneous quantification of oxygen and glucose consumption during visual stimulation in the human cortex
Epp, S. M.; Bose, A.; Belenya, R.; Kurcyus, K.; Ceballos, E. D.; Ranft, A.; Salas, E. V.; Bursche, M.; Preibisch, C.; Castrillon, G.; Riedl, V.
10.1101/2024.10.11.617828 — neuroscience — Posted on 2024-10-12
3599 HDAC Inhibitors recapitulate Human Disease-Associated Microglia Signatures in vitro
Haage, V. C.; Tuddenham, J. F.; Bautista, A.; White, C. C.; Garcia, F.; Patel, R.; Comandante-Lou, N.; Marshe, V.; Soni, R. K.; Sims, P. A.; Menon, V.; Sproul, A. A.; De Jager, P. L.
10.1101/2024.10.11.617544 — neuroscience — Posted on 2024-10-12
3601 Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab
Fertan, E.; Lam, J. Y. L.; Albertini, G.; Dewilde, M.; Wu, Y.; Akingbade, O. E. S.; Boeken, D.; English, E. A.; De Strooper, B.; Klenerman, D.
10.1101/2024.10.11.617910 — neuroscience — Posted on 2024-10-12
3603 Evolution of taste processing shifts dietary preference
Bertolini, E.; Muench, D.; Pascual, J.; Sgammeglia, N.; Ribeiro, C.; Auer, T. O.
10.1101/2024.10.11.617601 — neuroscience — Posted on 2024-10-12
3604 Chemo-Profiling by UPLC-QTOF-MS, GC-MS/MS analysis and In Vitro Bioactivity Assessment of Desmodium gangeticum DC.
Jagtap, M. A.; Magdum, A. B.; Lugade, V. V.; Kamble, P. S.; Jayannawar, D. P.; Nimbalkar, M. S.; Patil, S. A.
10.1101/2024.10.08.617169 — plant biology — Posted on 2024-10-12
3608 Improved protein binder design using -pairing targeted RFdiffusion
Sappington, I.; Toul, M.; Lee, D. S.; Robinson, S. A.; Goreshnik, I.; McCurdy, C.; Chan, T. C.; Buchholz, N.; Huang, B.; Vafeados, D.; Roullier, N.; Garcia-Sanchez, M.; Glögl, M.; Kim, C.; Watson, J. L.; Torres, S. V.; Verschueren, K. H. G.; Verstraete, K.; Hinck, C. S.; Bernard-Valle, M.; Coventry, B.; Sims, J. N.; Ahn, G.; Wang, X.; Hinck, A. P.; Jenkins, T. P.; Ruohola-Baker, H.; Banik, S.; Savvides, S. N.; Baker, D.
10.1101/2024.10.11.617496 — biochemistry — Posted on 2024-10-12
3609 Bond-centric modular design of protein assemblies
Wang, S.; Favor, A.; Kibler, R. D.; Lubner, J. M.; Borst, A. J.; Coudray, N.; Redler, R.; Chiang, H. T.; Sheffler, W.; Hsia, Y.; Li, Z.; Ekiert, D. C.; Bhabha, G.; Pozzo, L. D.; Baker, D.
10.1101/2024.10.11.617872 — biochemistry — Posted on 2024-10-12
3610 A polymerase ribozyme that can synthesize both itself and its complementary strand
Gianni, E.; Kwok, S. L. Y.; Wan, C. J. K.; Goeij, K.; Clifton, B.; Attwater, J.; Holliger, P.
10.1101/2024.10.11.617851 — biochemistry — Posted on 2024-10-12
3614 X-Tracker: Automated Analysis of Xenopus Tadpole Visual Avoidance Behavior
McKeown, C. R.; Ta, A. C.; Marshall, C. L.; McLain, N. J.; Archuleta, K. J.; Cline, H. T.
10.1101/2024.10.10.617688 — animal behavior and cognition — Posted on 2024-10-12
3616 Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies
Chernoff, C. S.; Belin-Rauscent, A.; Puaud, M.; Torrisi, S. A.; Fouyssac, M. S.; Nemeth, B.; Yu, C.; Higuera-Matas, A.; Jones, S.; Belin, D.
10.1101/2024.10.08.617254 — animal behavior and cognition — Posted on 2024-10-12
3620 Orthrus: Towards Evolutionary and Functional RNA Foundation Models
Fradkin, P.; Shi, R.; Isaev, K.; Frey, B. J.; Morris, Q.; Lee, L. J.; Wang, B.
10.1101/2024.10.10.617658 — genomics — Posted on 2024-10-12
3622 Single-nucleus transcriptomics of wing sexual dimorphism and scale cell specialization in sulphur butterflies
Loh, L. S.; Hanly, J. J.; Carter, A.; Chatterjee, M.; Tsimba, M.; Shodja, D. N.; Livraghi, L.; Day, C. R.; Reed, R. D.; McMillan, W. O.; Wray, G. A.; Martin, A.
10.1101/2024.10.10.617718 — developmental biology — Posted on 2024-10-12
3623 A piRNA regulating oogenesis and embryo development in cockroaches
Gonzalvo, J.; Farrus, N.; Escudero, J.; Pujal, D.; Bau, J.; Piulachs, M.-D.
10.1101/2024.10.10.617606 — developmental biology — Posted on 2024-10-12
3629 Filopodia-like Structures are Essential for Steroid Release
Simon, E.; Bonche, R.; Maarouf, Y.; Nawrot-Esposito, M.-P.; Romero, N. M.
10.1101/2024.10.10.617560 — developmental biology — Posted on 2024-10-12
3630 Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells
Rezvani, M.; Lewis, K.; Quach, S.; Iwasawa, K.; Weihs, J.; Reza, H.; Cai, Y.; Kimura, M.; Zhang, R.; Milton, Y.; Chaturvedi, P.; Thorner, K.; Nayak, R. C.; Munera, J. O.; Kramer, P.; Davis, B.; Balamurugan, A.; Ait Ahmed, Y.; Finke, M.; Behncke, R. Y.; Guillot, A.; Haegerling, R.; Polansky, J.; Bufler, P.; Cancelas, J.; Wells, J.; Yoshimoto, M.; Takebe, T.
10.1101/2024.10.11.617794 — developmental biology — Posted on 2024-10-12
3631 Chromatin Environment-Dependent Effects of DOT1L on Gene Expression in Male Germ Cells
Coulee, M.; de la Iglesia, A.; Blanco, M.; Gobe, C.; Lapoujade, C.; Ialy-Radio, C.; Alvarez Gonzalez, L.; Meurice, G.; Ruiz-Herrera, A.; Fouchet, P.; Cocquet, J.; El Khattabi, L.
10.1101/2024.10.12.617981 — molecular biology — Posted on 2024-10-12
3636 Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis
Male, F.; Kegawa, Y.; Blank, P. S.; Jimenez Munguia, I.; Sidik, S. M.; Valleau, D.; Lourido, S.; Lebrun, M.; Zimmerberg, J.; Ward, G. E.
10.1101/2024.10.12.618018 — microbiology — Posted on 2024-10-12
3638 Ethanol drinking sex-dependently alters cortical IL-1β synaptic signaling and cognitive behavior in mice
Liss, A.; Siddiqi, M.; Podder, D.; Scroger, M.; Vessey, G.; Martin, K.; Paperny, N.; Vo, K.; Astefanous, A.; Belachew, N.; Idahor, E.; Varodayan, F.
10.1101/2024.10.08.617276 — neuroscience — Posted on 2024-10-12
3639 A novel epigenetic clock for rhesus macaques unveils an association between early life adversity and epigenetic age acceleration
Bronk, G.; Lardenoije, R.; Koolman, L.; Klengel, C.; Dan, S.; Howell, B.; Morin, E.; Meyer, J.; Wilson, M.; Ethun, K.; Alvarado, M.; Raper, J.; Bravo-Rivera, H.; Kenwood, M.; Roseboom, P.; Quirk, G.; Kalin, N.; Binder, E.; Sanchez, M.; Klengel, T.
10.1101/2024.10.08.617208 — neuroscience — Posted on 2024-10-12
3641 Context-dependent Rhythmicity in Chimpanzee Displays
van der Vleuten, B.; Hovenkamp, V.; Varkevisser, J.; Spierings, M.
10.1101/2024.10.10.617583 — animal behavior and cognition — Posted on 2024-10-12
3642 PRC2 facilitates the transition from heterotrophy to photoautotrophy during seedling emergence
Samo, N.; Trejo Arellano, M. G.; Gahurova, L.; Ebert, A.; Riviere, Q.; Kubasek, J.; Aflaki, F.; Hönig Mondekova, H.; Schlereth, A.; Dubois, A.; Zhou, M.; Novak, O.; Santrucek, J.; Bouyer, D.; Roudier, F.; Kopka, J.; Mozgova, I.
10.1101/2024.10.08.616934 — plant biology — Posted on 2024-10-12
3643 A Novel Genomic Rearrangement in the Amaranthus palmeri Extrachromosomal Circular DNA Provides Dual Herbicide Resistance to Glyphosate and Glufosinate
Carvalho-Moore, P.; Borgato, E. A.; Cutti, L.; Porri, A.; Meiners, I.; Lerchl, J.; Norsworthy, J. K.; Patterson, E. L.
10.1101/2024.10.08.617243 — genomics — Posted on 2024-10-12
3646 Intranasal hemagglutinin protein boosters induce robust mucosal immunity and cross-protection against influenza A viral challenge
Moriyama, M.; Rodrigues, G.; Wang, J.; Hudak, A.; Dong, H.; Homer, R. J.; Weissman, D.; Ma, S.; Iwasaki, A.
10.1101/2024.10.10.616291 — immunology — Posted on 2024-10-12
3648 DeepFocus: A Transnasal Approach for Optimized Deep Brain Stimulation of Reward Circuit Nodes
Guo, Y.; Forssell, M.; Kusyk, D. M.; Jain, V.; Swink, I.; Corcoran, O.; Lee, Y.; Goswami, C.; Whiting, A. C.; Cheng, B. C.; Grover, P.
10.1101/2024.10.08.617133 — neuroscience — Posted on 2024-10-12
3651 SAMPL-seq reveals micron-scale spatial hubs in the human gut microbiome
Richardson, M.; Zhao, S.; Sheth, R. U.; Lin, L.; Qu, Y.; Lee, J.; Moody, T.; Ricaurte, D.; Huang, Y.; Velez-Cortes, F.; Urtecho, G.; Wang, H. H.
10.1101/2024.10.08.617108 — systems biology — Posted on 2024-10-12
3652 Whole genome resequencing of a global collection of Napier grass (Cenchrus purpureus) to explore global population structure and QTL governing yield and feed quality traits
Teshome, A.; Lire, H.; Higgins, J.; Olango, T.; Habte, E.; Negawo, A. T.; Muktar, M. S.; Assefa, Y.; Pereira, J. F.; Azevedo, A. L. S.; Machado, J. C.; Nyamongo, D. O.; Zhang, J.; Yan, Q.; Anderson, W.; De Vega, J.; Jones, C.
10.1101/2024.10.09.617134 — plant biology — Posted on 2024-10-12
3653 A diffusion model conditioned on compound bioactivity profiles for predicting high-content images
Cook, S.; Chyba, J.; Gresoro, L.; Quackenbush, D.; Qiu, M.; Kutchukian, P.; Martin, E.; Skewes-Cox, P.; Godinez, W. J.
10.1101/2024.10.10.616543 — bioinformatics — Posted on 2024-10-12
3655 Recursive Cleaning for Large-scale Protein Data via Multimodal Learning
Jiang, Z.; Zhang, S.; Cao, J.; Zhang, Q.; Liu, S.; Fang, Y.; Zhang, L.; Qing, R.; Xu, R.
10.1101/2024.10.08.617190 — bioengineering — Posted on 2024-10-12
3657 Regulating Human T Lymphocytes Through Magnetogenetic Tools
Helalat, S. H.; Tellez, R. H. C.; Kristinsdottir, H. T.; Petersen, A. D.; Islam, S. F.; Pardo, C. R.; Sun, Y.
10.1101/2024.10.08.617204 — bioengineering — Posted on 2024-10-12
3659 The thermotolerant Arabian killifish, Aphanius dispar, as a novel infection model for human fungal pathogens
Minhas, R.; Bedekovic, T.; Veale, T.; John, L. L. H.; Hamied, A. S.; Scrase, E.; Read, S.; Davies, C.; Gifford, H.; Farrer, R. A.; Bates, S.; Brand, A. C.; Ramsdale, M.; Kudoh, T.
10.1101/2024.10.08.617174 — animal behavior and cognition — Posted on 2024-10-12
3661 Single Cell Integration Characterises Metaplasia in Inflammatory Intestinal Diseases
Oliver, A. J.; Huang, N.; Li, R.; Bartolome-Casado, R.; Nilsen, H. R.; Gudino, V.; Melon-Ardanaz, C. d. I. B. e. R. d. E.; Fitzpatrick, M. E. B.; Provine, N. M.; Polanski, K.; Koplev, S.; Milchsack, L. M.; Dann, E.; Predeus, A. V.; Cakir, B.; To, K.; Prete, M.; Chapman, J. A.; Masi, A. C.; Stephenson, E.; Engelbert, J.; Lobentanzer, S.; Perera, S.; Richardson, L.; Kapuge, R.; Wilbrey-Clark, A.; Semprich, C. I.; Moy, M.; Ellams, S.; Tudor, C. L.; Joseph, P.; Garrido-Trigo, A.; Corraliza, C. d. I. B. e. R. d. E. M.; Oliver, T. R. W.; Hook, C. E.; Saez-Rodriguez, J.; James, K. R.; Meyer, K. B.; M
10.1101/2024.10.11.614415 — genomics — Posted on 2024-10-12
3665 Mapping Synaptic Ensembles Through In Vitro Functional Cell Assemblies
Zaccaria, C.; Malkoc, A.; Auslender, I.; Heydari, Y.; Canossa, M.; Vignoli, B.; Pavesi, L.
10.1101/2024.10.10.617167 — neuroscience — Posted on 2024-10-12
3666 Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system
Duplaa, C.; Delobel, V.; Boulestreau, R.; Rubin, S.; Vaurs, J.; Jaspard-Vinassa, B.; Busson, M.; Combrouze, C.; Proust, C.; Morel, J.-L.; Bontempi, B.; Mishra, A.; Debette, S.; Couffinhal, T.; Peghaire, C.
10.1101/2024.10.08.616723 — neuroscience — Posted on 2024-10-12
3667 A striosomal accumbens pathway drives compulsive seeking behaviors through an aversive Esr1+ hypothalamic-habenula circuit.
Contesse, T.; Yel Bektash, B.; Graziano, M.; Forastieri, C.; Contestabile, A.; Hahne, S.; Jung, F.; Nikolakopoulou, I.; Cao, X.; Skara, V.; Mantas, I.; Giatrellis, S.; Carlen, M.; Sandberg, R.; Calvigioni, D.; Meletis, K.
10.1101/2024.10.11.617042 — neuroscience — Posted on 2024-10-12
3669 Microscopic deconstruction of cortical circuit stimulation by transcranial ultrasound
Lemaire, T.; Yuan, Y.; Gellman, C.; LeMessurier, A. M.; Haiken Dray, S. R.; Little, J. P.; Froemke, R. C.; Shoham, S.
10.1101/2024.10.10.617091 — neuroscience — Posted on 2024-10-12
3671 A novel ex vivo model of muscle contraction to measure muscle endocrine and paracrine signalling
DABADIE, C.; BELAIDI, E.; MORETTA, A.; LEMARIE, L.; ALLARD, B.; KNEPPERS, A.; MOUNIER, R.
10.1101/2024.10.10.613648 — physiology — Posted on 2024-10-12
3672 Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies
Khamvongsa-Charbonnier, L.; Kremmer, L.; Torres, M.; Krifa, S.; Aubert, C.; Corbet, A.; Crespo, L.; Roder, L.; Perrin, L.; Arquier, N.
10.1101/2024.10.09.617032 — physiology — Posted on 2024-10-12
3673 Ruxolitinib clears CRYAB p.Arg120Gly aggregates through the ubiquitin-proteasome system
Alizoti, E.; Ewald, L.; Parretta, S.; Meyer-Jens, M.; Orthey, E.; Conze, C.; Carrier, L.; Robbins, J.; Singh, S. R.
10.1101/2024.10.11.615348 — pharmacology and toxicology — Posted on 2024-10-12
3676 PROPERMAB: an integrative framework for in silico prediction of antibody developability using machine learning
Li, B.; Luo, S.; Wang, W.; Xu, J.; Liu, D.; Shameem, M.; Mattila, J.; Franklin, M.; Hawkins, P. G.; Atwal, G. S.
10.1101/2024.10.10.616558 — bioinformatics — Posted on 2024-10-12
3680 Non-invasive brain-machine interface control with artificial intelligence copilots
Lee, J. Y.; Lee, S.; Mishra, A.; Yan, X.; McMahan, B.; Gaisford, T. B.; Kobashigawa, C.; Qu, M.; Xie, C.; Kao, J. C.
10.1101/2024.10.09.615886 — bioengineering — Posted on 2024-10-12
3681 New-to-nature PHA synthase design using deep learning
Tenkanen, T.; Ylinen, A.; Jouhten, P.; Penttila, M.; Castillo, S.
10.1101/2024.10.09.616406 — bioengineering — Posted on 2024-10-12
3685 Public RNA-seq data are not representative of global human diversity
Gallego Romero, I.; Rodenberg, G.; Arner, A. M.; Li, L.; Beasley, I. J. A.; Rossow, R.; Ryan, N.; Wang, S.; Lea, A. A.
10.1101/2024.10.11.617967 — genomics — Posted on 2024-10-12
3686 An atlas of conserved transcription factor binding sites reveals the cell type-resolved gene regulatory landscape of flowering plants
Baumgart, L. A.; Morales-Cruz, A.; Greenblum, S. I.; Wang, P.; Zhang, Y.; Yang, L.; Chen, C.; Dilworth, D. J.; Garretson, A. C.; Grosjean, N.; He, G.; Savage, E.; Yoshinaga, Y.; Blaby, I. K.; Daum, C. G.; O'Malley, R. C.
10.1101/2024.10.08.617089 — genomics — Posted on 2024-10-12
3687 The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions
Gill, P.; Fonnelop, A. E.; Hicks, T.; Xenophontos, S.; Cariolou, M.; van Oorschot, R.; Buckel, I.; Sukser, V.; Papic, S.; Merkas, S.; Kostic, A.; Marques Pereira, A.; Teutsch, C.; Forsberg, C.; Haas, C.; Petkovski, E.; Hass, F.; Masek, J.; Stosic, J.; Lee, Y. S.; Syn, C. K.-C.; Groombridge, L.; Trimborn, M.; Hadjivassiliou, M.; Breathnach, M.; Novackova, J.; Parson, W.; Hatzer-Grubwieser, P.; Pietikoinen, S.; Joas, S.; Willuweit, S.; Grethe, S.; Milicevic, T.; Hasselqvist, T.; Kallupurackal, V.; Stenzl, V.; Jansson, S.; Glocker, I.; Brunck, S.; Nyhagen, K.; Dyve Lingelem, A. B.; Autere, H.; Th
10.1101/2024.10.10.617148 — genetics — Posted on 2024-10-12
3688 Genome of the enigmatic watering-pot shell reveals adaptations of a living suction anchor
Sigwart, J.; Wong, N. L. W. S.; Gonzalez, V. L.; Machado, F. M.; Greve, C.; Schell, T.; Chen, Z.
10.1101/2024.10.08.617303 — evolutionary biology — Posted on 2024-10-12
3693 Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation
Deutsch, J. M.; Demko, A. M.; Jaiyesimi, O. A.; Foster, G.; Kindler, A.; Pitts, K. A.; Vekich, T.; Williams, G.; Walker, B. K.; Paul, V. J.; Garg, N.
10.1101/2024.10.08.617290 — systems biology — Posted on 2024-10-12
3694 The Curated Cancer Cell Atlas: comprehensive characterisation of tumours at single-cell resolution
Tyler, M.; Gavish, A.; Barbolin, C.; Tschernichovsky, R.; Hoefflin, R.; Mints, M.; Puram, S. V.; Tirosh, I.
10.1101/2024.10.11.617836 — cancer biology — Posted on 2024-10-12
3695 Mapping the Temporal Landscape of Breast Cancer Using Epigenetic Entropy
Monyak, D. L.; Holloway, S. T.; Gumbert, G. J.; Grimm, L. J.; Hwang, E. S.; Marks, J. R.; Shibata, D.; Ryser, M. D.
10.1101/2024.10.11.617056 — cancer biology — Posted on 2024-10-12
3697 Enhanced anti-tumor activity by Zinc Finger Repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs
David, M.; Schiele, P.; Monteferrario, D.; Saviane, G.; Martelli, A. E.; Dupont, C. F.; Jeanneau, C.; Marchetti, I.; Tadi, S. K.; Vahldick, J.; Truong, L. N.; Zhou, Y.; Sauer, I.; Schoning, W.; Na, I.-K.; Reik, A.; Frentsch, M.; de la Rosa, M.; Fenard, D.
10.1101/2024.10.11.613893 — cancer biology — Posted on 2024-10-12
3699 Basic fibroblast growth factor helps protect facial nerve cells in a freeze-induced paralysis model
Iwata, S.; Yamada, H.; Teraoka, M.; Tanaka, T.; Kimura, T.; Joko, T.; Tabata, Y.; Wakisaka, H.; Hato, N.
10.1101/2024.10.08.617179 — neuroscience — Posted on 2024-10-12
3702 High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
Howard, C. J.; Abell, N. S.; Osuna, B. A.; Jones, E. M.; Chan, L. Y.; Chan, H.; Artis, D. R.; Asfaha, J. B.; Bloom, J. S.; Cooper, A. R.; Liao, A.; Mahdavi, E.; Mohammed, N.; Su, A. L.; Uribe, G. A.; Kosuri, S.; Dickel, D. E.; Lubock, N. B.
10.1101/2024.10.11.617882 — synthetic biology — Posted on 2024-10-12
3704 The genetic basis of replicated bullseye pattern reduction across the Trionum Complex
Yeo, M. T. S.; Fairnie, A. L. M.; Travaglia, V.; Walker, J. F.; riglet, l.; Zeyrek, S.; Moyroud, E.
10.1101/2024.10.10.617677 — plant biology — Posted on 2024-10-12
3705 Chromosome-scale genome assembly and de novo annotation of Alopecurus aequalis.
Wright, J.; Baker, K.; Barker, T.; Catchpole, L.; Durrant, A.; Fraser, F.; Gharbi, K.; Harrison, C.; Henderson, S.; Irish, N.; Kaithakottil, G.; Leitch, I. J.; Li, J.; Lucchini, S.; Neve, P.; Powell, R.; Rees, H.; Swarbreck, D.; Watkins, C.; Wood, J.; McTaggart, S.; Hall, A.; MacGregor, D. R.
10.1101/2024.10.09.616956 — plant biology — Posted on 2024-10-12
3706 Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells.
Ho, C.-H.; Dippel, M. A.; McQuade, M. S.; Mishra, A.; Pribitzer, S.; Nguyen, L. P.; Hardy, S.; Chandok, H.; Chardon, F.; McDiarmid, T. A.; DeBerg, H. A.; Buckner, J. H.; Shendure, J.; de Boer, C. G.; Guo, M.; Tewhey, R.; Ray, J. P.
10.1101/2024.10.07.617092 — genetics — Posted on 2024-10-12
3708 Induction of the ISR by AB5 subtilase cytotoxin drives IFN-I expression in pDCs via STING activation
Pierre, P.; Barros, D.; Ferreira, B.; Garcia-Gonzalez, P.; Carbone, F.; Luka, M.; Leite-Pinheiro, F. C.; Antas, P.; Mendes, A.; Machado, M.; Zhang, L.; Cresci, M.; Galliot, L.; Gigan, J.; Reverendo, M.; Su, B.; Paton, A. W.; Paton, J. C.; Rocchi, S.; Rieux-laucat, F.; Arguello, R. J.; Nal Rogier, B.; Liang, Y.; Menager, M. M.; Gatti, E.; Almeida, C.
10.1101/2024.10.07.616986 — immunology — Posted on 2024-10-12
3710 Anxious/depressed individuals exhibit disrupted frontotemporal synchrony during cognitive conflict encoding
Shekara, A.; Ross, A.; Soper, D. J.; Paulk, A. C.; Cash, S. S.; Shear, P. K.; Sheehy, J. P.; Basu, I.
10.1101/2024.10.10.617540 — neuroscience — Posted on 2024-10-12
3711 Apollo: A comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell
Perera, D.; Li, E.; van der Meer, F.; Lynch, T.; Gill, J.; Church, D. L.; Huber, C. D.; van Marle, G.; Platt, A.; Long, Q.
10.1101/2024.10.07.617101 — bioinformatics — Posted on 2024-10-12
3713 Prolactin and DNA damage trigger an anti-breast cancer cellimmune response
Karayazi Atici, O.; Govindrajan, N.; Lopetegui-Gonzalez, I.; Finney, C. A. M.; Shemanko, C. S.
10.1101/2020.08.31.274357 — cancer biology — Posted on 2024-10-12
3715 SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis
Breunig, K.; Lei, X.; Montalbano, M.; Guardia, G.; Ostadrahimi, S.; Alers, V.; Kosti, A.; Chiou, J.; Klein, N.; Vinarov, C.; Wang, L.; Li, M.; Song, W.; Kraus, W. L. O.; Libich, D. S.; Tiziani, S.; Weintraub, S. T.; Galante, P. A. F.; Penalva, L. O.
10.1101/2024.03.22.586270 — genomics — Posted on 2024-10-12
3716 Foxtrot migration and dynamic over-wintering range of an arctic raptor
Pokrovsky, I.; Curk, T.; Dietz, A.; Fufachev, I.; Kulikova, O.; Rossler, S.; Wikelski, M.
10.1101/2023.03.13.532370 — ecology — Posted on 2024-10-12
3717 Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential
Radnai, L.; Young, E. J.; Kikuti, C.; Hafenbreidel, M.; Stremel, R. F.; Lin, L.; Toth, K.; Pasetto, P.; Jin, X.; Patel, A.; Conlon, M.; Briggs, S.; Heidsleck, L.; Sweeney, L.; Sellers, J. R.; Krieger-Burke, T.; Rumbaugh, G.; Cameron, M. D.; Surman, M.; Houdusse, A.; Griffin, P. R.; Kamenecka, T. M.; Miller, C. A.
10.1101/2024.10.07.617018 — cell biology — Posted on 2024-10-12
3718 TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress.
Hwang, S.-P.; Liao, H.; Barondeau, K.; Han, X.; Herbert, C.; McConnie, H.; Shekar, A.; Pestov, D.; Limbach, P. A.; Chang, J. T.; Denicourt, C.
10.1101/2024.05.02.591343 — molecular biology — Posted on 2024-10-12
3719 Rethinking Dormancy: Antibiotic Persisters are Metabolically Active, Non-Growing Cells
Rahman, K. M. T.; Amaratunga, R.; Butzin, X. Y.; Singh, A.; Hossain, T.; Butzin, N. C.
10.1101/2023.12.09.570944 — microbiology — Posted on 2024-10-12
3720 Fibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies
Jakobsson, J. E.; Menezes, J.; Krock, E.; Hunt, M. A.; Carlsson, H.; Vaivade, A.; Emami Khoonsari, P.; Agalave, N. M.; Sandstrom, A.; Kadetoff, D.; Tour Sohlin, J.; Erngren, I.; Al-Grety, A.; Freyhult, E.; Sandor, K.; Kosek, E.; Svensson, C. I.; Kultima, K.
10.1101/2024.10.11.617524 — neuroscience — Posted on 2024-10-12
3722 Characterizing the temporal dynamics and maturation of brain activity during sleep: an EEG microstate study in preterm and full-term infants.
Adibpour, P.; Nasser, H.; Pedoux, A.; Devisscher, L.; Elbaz, N.; Ghozland, C.; Hinnekens, E.; Neumane, S.; Kabdebon, C.; Lefebvre, A.; Kaminska, A.; Hertz-Pannier, L.; Heneau, A.; Sibony, O.; Alison, M.; Delanoe, C.; Delorme, R.; Barbu-Roth, M.; Biran, V.; Dubois, J.
10.1101/2024.03.19.585608 — neuroscience — Posted on 2024-10-12
3723 Representations of the intrinsic value of information in mouse orbitofrontal cortex
Bussell, J. J.; Badman, R. P.; Marton, C. D.; Bromberg-Martin, E. S.; Abbott, L.; Rajan, K.; Axel, R.
10.1101/2023.10.13.562291 — neuroscience — Posted on 2024-10-12
3726 Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression
Valenti, G.; Laise, P.; Takahashi, R.; Wu, F.; Ruan, T.; Vasciaveo, A.; Jiang, Z.; Sunagawa, M.; Middelhoff, M.; Nienhuser, H.; Fu, N.; Malagola, E.; Hayakawa, Y.; Iuga, A. C.; Califano, A.; Wang, T. C.
10.1101/2024.08.30.610508 — cancer biology — Posted on 2024-10-12
3727 Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering
De, S.; Zhou, M.; Brown, Z. P.; Burton-Smith, R. N.; Hashem, Y.; Pestova, T.; Hellen, C. U. T.; Frank, J.
10.1101/2024.10.11.617640 — biophysics — Posted on 2024-10-12
3729 Systematic Mining of gut microbiota biomarkers for IBD
Yuchen, Z.; Lai, W.; Meiling, W.; Shirong, L.; Qing, L.; Qi, L.; Feng long, Y.
10.1101/2024.10.10.617522 — bioinformatics — Posted on 2024-10-12
3731 Defacing biases visual quality assessments of structural MRI
Provins, c.; Savary, E.; Sanchez, T.; Mullier, E.; Barranco, J.; Fischi-Gomez, E.; Aleman-Gomez, Y.; Richiardi, J.; Poldrack, R. A.; Hagmann, P.; Esteban, O.
10.1101/2024.10.11.617777 — bioinformatics — Posted on 2024-10-12
3738 Evolution of promoter-proximal pausing enabled a new layer of transcription control
Chivu, A. G.; Basso, B. A.; Abuhashem, A.; Leger, M. M.; Barshad, G.; Rice, E. J.; Vill, A. C.; Wong, W.; Chou, S.-P.; Chovatiya, G.; Brady, R.; Smith, J.; Wikramanayake, A.; Arenas-Mena, C.; Brito, I. L.; Ruiz-Trillo, I.; Hadjantonakis, A.-K.; Lis, J. T.; Lewis, J. J.; Danko, C. G.
10.1101/2023.02.19.529146 — evolutionary biology — Posted on 2024-10-12
3739 A can of worms: estimating the global number of earthworm species
Decaens, T.; Brown, G. G.; Cameron, E. K.; Csuzdi, C.; Eisenhauer, N.; Gerard, S.; Goulpeau, A.; Hedde, M.; James, S.; Lapied, E.; Maggia, M.-E.; Marchan, D. F.; Mathieu, J.; Phillips, H. R.; Marcon, E.
10.1101/2024.09.08.611896 — ecology — Posted on 2024-10-12
3742 Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway
Isotani, R.; Igarashi, M.; Miura, M.; Naruse, K.; Kuranami, S.; Katoh, M.; Nomura, S.; Yamauchi, T.
10.1101/2024.01.02.573853 — cell biology — Posted on 2024-10-12
3744 Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing
De Castro, I.; Schuster, L.; Gomez, C. P.; Glavas, D.; Udupa, A.; Vazquez, M. R.; Symens, T.; Tulcan, G.; de las Heras, J. I.; Reinhardt, R.; Trojanowski, J.; Harz, H.; Stumberger, G.; Leonhardt, H.; Schirmer, E. C.; Saka, S.; Laketa, V.; Lusic, M.
10.1101/2024.09.30.615666 — cell biology — Posted on 2024-10-12
3746 Circulating microRNAs as biomarkers of chronic kidney disease and its association with renal and cardiovascular outcomes in non-dialysis patients
Ramil - Gomez, O.; Cerqueira, A.; Moura, S.; Carvalho, E.; Paulo, N.; Brandao, I.; Santos, J.; Quaranta, P.; Sousa, M. J.; Pinho, A.; Diniz, H.; Almeida, M. I.; Pestana, M.; Alencastre, I. S.
10.1101/2024.10.10.617547 — molecular biology — Posted on 2024-10-12
3748 Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer
Wu, Y.; Huang, X.; Huang, Y.; Huang, Z.; Chen, C.; Qin, M.; Wang, Z.; He, F.; Tang, B.; Long, C.; Mo, X.; Liu, J.; Tang, W.
10.1101/2024.10.10.617644 — microbiology — Posted on 2024-10-12
3751 Effects of oral contraceptive pills on brain networks: A replication and extension
Haase, G.; Liu, J. G.; Jordan, T.; Rapkin, A.; London, E. D.; Petersen, N.
10.1101/2024.10.10.617472 — neuroscience — Posted on 2024-10-12
3753 Co-cultivating rice plants with Azolla filiculoides modifies root architecture and timing of developmental stages
Cannavo', S.; Paleni, C.; Costarelli, A.; Valeri, M. C.; Cerri, M.; Saccomanno, A.; Gregis, V.; Chini Zittelli, G.; Dobrev, P. I.; Reale, L.; Kater, M. M.; Paolocci, F.
10.1101/2024.10.02.615985 — plant biology — Posted on 2024-10-12
3755 Isolated human Fos promoter in plasmid DNA is overactive
Gorbunov, A.; Fedorov, D. A.; Kvitko, O.; Lopina, O.; Klimanova, E.
10.1101/2024.10.11.617784 — molecular biology — Posted on 2024-10-11
3757 The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria
Schubert, K.; Braly, M.; Zhang, J.; Muscolo, M. E.; Lam, H. N.; Hug, K.; Moore, H.; McCausland, J. W.; Terciano, D.; Lowe, T.; Lesser, C. F.; Jacobs-Wagner, C.; Wang, H.; Auerbuch, V.
10.1101/2024.10.11.617751 — microbiology — Posted on 2024-10-11
3758 The fire blight pathogen Erwinia amylovora enters apple leaves through naturally-occurring wounds from the abscission of trichomes
Millett, F.; Standish, J.; Scanley, J.; Miller, K.; Inguagiato, J.; Zuverza-Mena, N.; Abril, M.; Robinson, V.; Li, Y.; Sundin, G. W.; Zeng, Q.
10.1101/2024.10.10.617712 — microbiology — Posted on 2024-10-11
3761 GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18
Wagner, A. S.; Smith, F. M.; Bennin, D. A.; Votava, J. A.; Datta, R.; Giese, M. A.; Zhao, W.; Skala, M.; Fan, J.; Keller, N. P.; Huttenlocher, A.
10.1101/2024.10.11.617742 — microbiology — Posted on 2024-10-11
3764 Mapping AAV capsid sequences to functions through function-guided in silico evolution
Zheng, H.; Guo, B.; Mo, A.; Wei, H.; Wu, Y.; Lin, X.; Jiang, H.; Li, H.; Zhang, Y.; Song, Z.; Ni, X.; Huang, Y.; Gu, X.; Yu, B.; Cheng, N.; Wang, X.
10.1101/2024.10.11.617764 — bioengineering — Posted on 2024-10-11
3765 Torsion-Induced Traumatic Optic Neuropathy (TITON): A Physiologically Relevant Animal Model of Traumatic Optic Neuropathy
Ryan, A. K.; Asemota, B. I.; Heisler-Taylor, T.; Mello, C.; Rodriguez, L.; Sponsel, W. E.; Racine, J.; Rex, T. S.; Glickman, R. D.; Reilly, M. A.
10.1101/2024.10.08.617086 — bioengineering — Posted on 2024-10-11
3767 Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats
Vazquez, J. M.; Lauterbur, M. E.; Mottaghinia, S.; Bucci, M.; Fraser, D.; Gray-Sandoval, G.; Gaucherand, L.; Haidar, Z. R.; Han, M.; Kohler, W.; Lama, T. M.; Lecorf, A.; Maesen, S.; McMillan, D.; Li, S.; Lo, J.; Rey, C.; Capel, S. L.; Singer, M.; Slocum, K.; Thomas, W.; Debelak Tyburec, J.; Santos Villa, S. G.; Miller, R.; Buchalski, M.; Vazquez-Medina, J. P.; Pfeffer, S.; Etienne, L.; Enard, D.; Sudmant, P. H.
10.1101/2024.10.10.617725 — genomics — Posted on 2024-10-11
3768 DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project
Mariner, B. L.; McCoy, B. M.; Greenier, A.; Brassington, L.; Silkas, E.; Adjangba, C.; Marye, A.; Harrison, B. R.; Bamberger, T.; Algavi, Y.; Muller, E.; Harris, A.; Rout, E.; The Dog Aging Project Consortium, ; Avery, A.; Borenstein, E.; Promislow, D.; Snyder-Mackler, N.
10.1101/2024.10.08.617286 — genomics — Posted on 2024-10-11
3769 CREB3 gain of function variants protect against ALS
Megat, S.; Marques, C.; Hernan Godoy, M.; Sellier, C.; Stuart-Lopez, G.; Dirrig-Grosch, S.; Gorin, C.; Brunet, A.; Fischer, M.; Keime, C.; Kessler, P.; Mendoza-Parra, M. A.; Scholz, S. W.; Ferrucci, L.; Ludolph, A.; Traynor, B.; Chio, A.; Dupuis, L.; Rouaux, C.
10.1101/2024.10.10.617542 — genomics — Posted on 2024-10-11
3770 rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload
Leggieri, A.; Judit Garcia-Gonzalez, J.; Hosseinian, S.; Ashdown, P.; Anagianni, S.; Wang, X.; Havelange, W.; Fernandez-Castillo, N.; Cormand, B.; Brennan, C. H.
10.1101/2024.10.09.616976 — genetics — Posted on 2024-10-11
3771 A collection of split-Gal4 drivers targeting conserved signaling ligands in Drosophila
Ewen-Campen, B.; Joshi, N.; Herman, A. S.; Thakkar, T.; Zirin, J.; Perrimon, N.
10.1101/2024.10.10.617664 — genetics — Posted on 2024-10-11
3772 Odorant receptors tuned to isothiocyanates in Drosophila melanogaster and their evolutionary expansion in herbivorous relatives
Matsunaga, T.; Reisenman, C. E.; Goldman-Huertas, B. M.; Rajshekar, S.; Suzuki, H. C.; Tadres, D.; Wong, J.; Louis, M.; Ramirez, S. R.; Whiteman, N. K.
10.1101/2024.10.08.617316 — evolutionary biology — Posted on 2024-10-11
3773 SMYD5 is a ribosomal methyltransferase which trimethylates RPL40 lysine 22 through recognition of a KXY motif
Hamey, J. J.; Shah, M.; Wade, J. D.; Bartolec, T. K.; Wettenhall, R. E.; Quinlan, K. G.; Williamson, N. A.; Wilkins, M. R.
10.1101/2024.10.10.616381 — molecular biology — Posted on 2024-10-11
3774 RAD51 Paralogs and RAD51 Paralog Complexes BCDX2 and CX3 Interact with BRCA2
Thrasher, J. G.; Fagunloye, A. A. G.; Justiniano, F. S.; Bernstein, K. A.; Jensen, R. B.
10.1101/2024.10.10.617680 — molecular biology — Posted on 2024-10-11
3775 Identifying sexually dimorphic circulating microRNAs in gonochoristic and hermaphroditic marine fish species.
Geffroy, B.; Camille, H.; Blondeau-Bidet, E.; Mialhe, X.; Bajek, A.; Falguiere, J.-C.; Guiguen, Y.; Bobe, J.
10.1101/2024.10.11.617774 — molecular biology — Posted on 2024-10-11
3776 RPS19 and RPL5, the most commonly mutated genes in Diamond Blackfan anemia, impact DNA double-strand break repair
DeCleene, N. F.; Asik, E.; Sanchez, A.; Williams, C. L.; Kabotyanski, E. B.; Zhao, N.; CHATTERJEE, N.; Miller, K.; Wang, Y. H.; Bertuch, A. A.
10.1101/2024.10.10.617668 — molecular biology — Posted on 2024-10-11
3777 Provirus deletion from Haloferax volcanii affects motility, stress resistance and CRISPR RNA expression
Di Cianni, N.; Bolsinger, S.; Brendel, J.; Raabe, M.; Koenig, S.; Mitchell, L.; Bischler, T.; Grafenhan, T.; Read, C.; Erdmann, S.; Allers, T.; Walther, P.; Urlaub, H.; Dyall-Smith, M.; Pfeiffer, F.; Marchfelder, A.
10.1101/2024.10.11.617810 — molecular biology — Posted on 2024-10-11
3778 Novel Transgenic Humanized Alpha-1 Antitrypsin Deficiency Mouse Model on Murine SERPINA1 Null Background
Oshins, R.; Aranyos, A. M.; Grey, S.; Mohammad, N.; Lu, Y.; Lascano, J. E.; Flagg, T.; Serban, K.; Brantly, M.; Khodayari, N.
10.1101/2024.10.11.617858 — molecular biology — Posted on 2024-10-11
3779 Intranasal delivery of a broadly neutralizing single domain antibody targeting ACE2 protects against SARS-CoV-2 infection
Blachier, S.; Fernandez, I.; Conquet, L.; Giraud, E.; Staropoli, I.; Michel, V.; Szilagyi, F.; Guez, S.; Boucharlat, A.; Chiaravalli, J.; Tran-Rajau, J.; Dufour, E.; Petres, S.; Planas, D.; Montagutelli, X.; Agou, F.; Rey, F. A.; Lafaye, P.; Enninga, J.; Ayme, G.; Schwartz, O.; Brelot, A.
10.1101/2024.10.11.617877 — microbiology — Posted on 2024-10-11
3781 Metabolic reprogramming tips vaccinia virus infection outcomes by stabilizing interferon-g induced IRF1
Chang, T.; Alvarez, J.; Chappidi, S.; Crockett, S.; Sorouri, M.; Orchard, R. C.; Hancks, D. C.
10.1101/2024.10.10.617691 — microbiology — Posted on 2024-10-11
3782 Effect of inactivated conditioned media from DENV-2-infected endothelial cells on epithelial cell healing: live cell imaging analysis.
Hincapie, V.; Cardona-Gomez, J. C.; Gallego-Gomez, J. C.; Villarreal-Julio, R. G.; Blandon, J.; Ordonez, B. E.; Perez, G. A.; Cuartas-Lopez, A. M.
10.1101/2024.10.11.617825 — microbiology — Posted on 2024-10-11
3783 Vibrio are a potential source of novel colistin-resistance genes in European coastal environments
Saad, J.; Boulo, V.; Goudenege, D.; Broquard, C.; Andree, K.; Auguste, M.; Petton, B.; Labreuche, Y.; Tris, P.; Furones, D.; Gil, A.; Vezzulli, L.; Corno, G.; Di Cesare, A.; Koechlin, H.; Labadie-Lafforgue, E.; COURTAY, G.; ROMATIF, O.; Pouzadoux, J.; ESCOUBAS, J.-M.; MUNARON, D.; Charriere, G. M.; Toulza, E.; Travers, M.-A.; MONTAGNANI, C.; Wegner, M.; Destoumieux-Garzon, D.
10.1101/2024.10.10.617683 — microbiology — Posted on 2024-10-11
3784 Arctic Ocean virus communities: seasonality, bipolarity, and prokaryotic interactions
Calayag, A.; Priest, T.; Oldenburg, E.; Muschiol, J.; Popa, O.; Wietz, M.; Needham, D.
10.1101/2024.10.11.617772 — microbiology — Posted on 2024-10-11
3786 Functional Activity and Binding Specificity of small Ankyron Repeat Proteins against SARS-CoV-2 variants
Park, Y.-J.; Jankowski, W.; Hurst, N. C.; Fry, J. W.; Schwabe, N. F.; Tan, L. C. C.; Sauna, Z. E.
10.1101/2024.10.11.617752 — immunology — Posted on 2024-10-11
3787 Chai-1: Decoding the molecular interactions of life
Chai Discovery (Chai), ; Boitreaud, J.; Dent, J.; McPartlon, M.; Meier, J.; Reis, V.; Rogozhonikov, A.; Wu, K.
10.1101/2024.10.10.615955 — synthetic biology — Posted on 2024-10-11
3791 Genome-wide CRISPR/Cas9 screen reveals factors that influence the susceptibility of tumor cells to NK cell-mediated killing
Guia, S.; Fenis, A.; Galluso, J.; Medjouel, H.; Escaliere, B.; Modelska, A.; Vienne, M.; Lopes, N.; Pouchin, A.; Rossi, B.; Gauthier, L.; Roulland, S.; Vivier, E.; NARNI-MANCINELLI, E.
10.1101/2024.10.08.615667 — immunology — Posted on 2024-10-11
3793 ORCO: Ollivier-Ricci Curvature-Omics: an unsupervised method for analyzing robustness in biological systems
Simhal, A. K.; Weistuch, C.; Murgas, K. A.; Grange, D.; Zhu, J.; Oh, J. H.; Elkin, R.; Deasy, J. O.
10.1101/2024.10.06.616915 — bioinformatics — Posted on 2024-10-11
3796 The unique and enigmatic spirochete symbiont of latrunculid sponges
Waterworth, S. C.; Solomons, G. M.; Kalinski, J.-C. J.; Madonsela, L. S.; Parker-Nance, S.; Dorrington, R. A.
10.1101/2024.05.23.595633 — microbiology — Posted on 2024-10-11
3802 Identification of targetable epigenetic vulnerabilities in uveal melanoma
Yenisehirli, G.; Borges, S.; Braun, S. S.; Zuniga, A. N.; Quintana, G. I.; Kuznetsoff, J. N.; Rodriguez, S.; Adis, E. V.; Lopez, S.; Dollar, J. J.; Stathias, V.; Volmar, C. H.; Karaca, E.; Brothers, S.; Bilbao, D.; Harbour, J. W.; Correa, Z. M.; Kurtenbach, S.
10.1101/2024.10.11.617464 — cancer biology — Posted on 2024-10-11
3805 Visualization of breast cancer using contrast-enhanced optical coherence elastography based on tissue heterogeneity
Li, J.; Foo, K. Y.; Sanderson, R. W.; Zilkens, R.; Hardie, M.; Gale, L.; Yeow, Y. L.; Green, C.; Abdul-Aziz, F.; Hamzah, J.; Stephenson, J.; Tayaran, A.; Cid Fernandez, J.; Jackson, L.; Chin, S. L.; Hamza, S.; Rijhumal, A.; Saunders, C. M.; Kennedy, B. F.
10.1101/2024.10.09.617341 — bioengineering — Posted on 2024-10-11
3808 TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact
Canson, D. M.; Llinares-Burguet, I.; Fortuno, C.; Sanoguera-Miralles, L.; Bueno-Martinez, E.; de la Hoya, M.; Spurdle, A. B.; Velasco-Sampedro, E. A.
10.1101/2024.10.07.617118 — genetics — Posted on 2024-10-11
3809 The influence of soft tissue volume on estimates of skeletal pneumaticity: implications for fossil archosaurs
Burton, M. G.; Benito, J.; Mellor, K.; Smith, E.; Martin-Silverstone, E.; O'Connor, P.; Field, D. J.
10.1101/2024.10.08.617080 — evolutionary biology — Posted on 2024-10-11
3814 Metabolomic Profiling Reveals Potential of Fatty Acids as Regulators of Stem-like Exhausted CD8 T Cells During Chronic Viral Infection
Kazane, K. R.; Labarta-Bajo, L.; Zangwill, D. R.; Liimatta, K.; Vargas, F.; Weldon, K. C.; Dorrestein, P. C.; Zuniga, E. I.
10.1101/2024.10.07.617124 — immunology — Posted on 2024-10-11
3815 IgG autoantibodies in bullous pemphigoid directly induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes:
Bao, L.; Guerrero-Juarez, C. F.; Li, J.; Pigors, M.; Emtenani, S.; Liu, Y.; Ahmed, A.; Ishii, N.; Hashimoto, T.; Perez White, B. E.; Green, S.; Kunstman, K.; Nowak, N. C.; Cole, C.; Macias, V.; Sverdlov, M.; McAlexander, A.; McCrae, C.; Nazaroff, C. D.; Schmidt, E.; Amber, K. T.
10.1101/2024.10.07.616103 — immunology — Posted on 2024-10-11
3816 Repertoire, function, and structure of serological antibodies induced by the R21/Matrix-M malaria vaccine
McDaniel, J. R.; Voss, W. N.; Bowyer, G.; Rush, S. A.; Spencer, A. J.; Bellamy, D.; Ulaszewska, M.; Goike, J.; Gregory, S.; King, C. R.; McLellan, J. S.; Hill, A. V. S.; Georgiou, G.; Ewer, K. J.; Ippolito, G. C.
10.1101/2024.10.07.617084 — immunology — Posted on 2024-10-11
3818 T-scope V4: miniaturized microscope for optogenetic tagging in freely behaving animals
Wang, Y.; Vergara, P.; Hasegawa, S.; Tomita, N.; Cherasse, Y.; Naoi, T.; Sakurai, T.; Sugaya, Y.; Kano, M.; Sakaguchi, M.
10.1101/2024.10.07.616920 — neuroscience — Posted on 2024-10-11
3820 Longitudinal multi-omics reveals pathogenic TSC2 variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis Complex
Niu, W.; Yu, S.; Li, X.; Wang, Z.; Chen, R.; Michalski, C.; Jahangiri, A.; Zohdy, Y.; Chern, J. J.; Whitworth, T. J.; Wang, J.; Xu, J.; Zhou, Y.; Qin, Z.; Li, B.; Gambello, M. J.; Peng, J.; Wen, Z.
10.1101/2024.10.07.617121 — neuroscience — Posted on 2024-10-11
3821 Isotope Encoded Chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity
Wood, J. I.; Dulewicz, M.; Ge, J.; Stringer, K.; Szadziewska, A.; Desai, S.; Koutarapu, S.; Hajar, H. B.; Blennow, K.; Zetterberg, H.; Cummings, D. M.; Savas, J. N.; Edwards, F. A.; Hanrieder, J.
10.1101/2024.10.08.617019 — neuroscience — Posted on 2024-10-11
3823 Effects of oral contraceptive pills on brain networks: A replication and extension
Haase, G.; Jordan, T.; Liu, J. G.; Rapkin, A.; London, E. D.; Petersen, N.
10.1101/2024.10.10.617472 — neuroscience — Posted on 2024-10-11
3824 Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
Chedid, J.; Li, Y.; Labrador-Garrido, A.; Abu-Bonsrah, D.; Pavan, C.; Fraser, T.; Zhong, M.; Johnston, J. A.; Thompson, L. H.; Kirik, D.; Parish, C.; Halliday, G.; Sue, C.; Wali, G.; Dzamko, N.
10.1101/2024.10.07.617117 — neuroscience — Posted on 2024-10-11
3826 An abstract relational map emerges in the human medial prefrontal cortex with consolidation
Baram, A.; Nili, H.; Barreiros, I.; Samborska, V.; Behrens, T. E.; Garvert, M. M.
10.1101/2024.10.11.617652 — neuroscience — Posted on 2024-10-11
3827 Multiple neural pathways to successful visual short-term memory across the adult lifespan
Jansen, M. G.; Salami, A.; Martinez, F. R.; Mitchell, D. J.; Oosterman, J. M.; Cam-CAN, ; Geerligs, L.
10.1101/2024.10.08.617160 — neuroscience — Posted on 2024-10-11
3828 Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites
Lawore, D. C.; Jena, S.; Berard, A. R.; Birse, K.; Lamont, A.; Mackelprang, R. D.; Noel-Romas, L.; Perner, M.; Hou, X.; Irungu, E.; Mugo, N.; Knodel, S.; Muwonge, T. R.; Katabira, E.; Hughes, S. M.; Levy, C.; Calienes, F. L.; Baeten, J. M.; Celum, C.; Hladik, F.; Lingappa, J. R.; Burgener, A. D.; Green, L. N.; Brubaker, D. K.
10.1101/2024.10.10.616351 — systems biology — Posted on 2024-10-11
3829 NPF4.1 imports embryo-derived GA4 to the endosperm to promote seed germination
Sirlin-Josserand, M.; Sakvarelidze-Achard, L.; Pflieger, D.; Daviere, J.-M.; Achard, P.
10.1101/2024.10.07.617022 — plant biology — Posted on 2024-10-11
3831 The utility of single-cell RNA sequencing data in predicting plant metabolic pathway genes
Ma, J.; Zou, L.; Wang, Z.; Wang, X.; Zuo, X.; Wang, F.; Wang, Z.; Li, Z.; Li, L.; Wang, P.
10.1101/2024.10.07.617125 — plant biology — Posted on 2024-10-11
3836 Anti-tumor activity of camptothecin analog conjugate of a RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.
Toh, Y.; Wu, L.; Tu, J.; Liang, Z.; Aldana, A. M.; Li, L.; Wen, J. J.; Pan, S.; Rowe, J. H.; Hensel, M. E.; Hodo, C. L.; Finch, R. A.; Carmon, K. S.; Liu, Q. J.
10.1101/2024.10.08.616548 — pharmacology and toxicology — Posted on 2024-10-11
3837 Arginine methylation coordinates with phosphorylation to regulate NADP+ synthesis
Zhu, Y.; Zhang, W.; Hu, M.; Xing, X.; Li, Y.; Zhang, H.; Zhao, Y.; Chen, L.; Zhang, C.; Chen, Y.; Qin, W.; Han, S.; Pei, H.; Zhang, P.
10.1101/2024.10.11.617635 — cancer biology — Posted on 2024-10-11
3838 Apollo: A comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell
Perera, D.; Li, E.; van der Meer, F.; Lynch, T.; Gill, J.; Church, D. L.; Huber, C. D.; van Marle, G.; Platt, A.; Long, Q.
10.1101/2024.10.07.617101 — bioinformatics — Posted on 2024-10-11
3843 Tuning Insulin Receptor Signaling Using De Novo Designed Agonists
Wang, X.; Cardoso, S.; Cai, K.; Venkatesh, P.; Hung, A.; Ng, M.; Hall, C.; Coventry, B.; Lee, D.; Chowhan, R.; Gerben, S.; Li, J.; An, W.; Hon, M.; Accili, D.; Bai, X.; Choi, E.; Baker, D.
10.1101/2024.10.07.617068 — bioengineering — Posted on 2024-10-11
3844 ProFit-1D for quantifying J-difference edited data at 3T
Chan, K. L.; Borbath, T.; Sherlock, S.; Maher, E. A.; Patel, T.; Henning, A.
10.1101/2024.10.07.616795 — bioengineering — Posted on 2024-10-11
3847 Well-resolved phylogeny reveals multiple origins of keel flowers during the diversification of papilionoid legumes
Cai, L.; Cardoso, D.; Tressel, L. G.; Lee, C.; Shrestha, B.; Choi, I.-S.; Lima, H. C.; Queiroz, L. P.; Ruhlman, T. A.; Jansen, R. K.; Wojciechowski, M. F.
10.1101/2024.10.07.617045 — evolutionary biology — Posted on 2024-10-11
3850 Relation of CMV and brain atrophy to trajectories of immunosenescence in diverse populations
Touil, H.; Luquez, T.; Comandante-Lou, N.; Lee, A. J.; Fujita, M.; Habeck, C.; Kroshilina, A.; Hegewisch-Solloa, E.; McInvale, J.; Zuroff, L.; Isnard, S.; Walker, E.; Zhang, L.; Routy, J.-P.; Zhang, Y.; Mace, E. M.; Klotz, L.; Wiendl, H.; Xia, Z.; Bar-Or, A.; Menon, V.; Stern, Y.; De Jager, P. L.
10.1101/2024.10.07.614568 — immunology — Posted on 2024-10-11
3851 Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction.
Grace, P. S.; Peters, J. M.; Sixsmith, J.; Lu, R.; Fenderson, B. A.; Vickers, A.; Slein, M. D.; Irvine, E. B.; McKitrick, T.; Wei, M.-H.; Cummings, R. D.; Wallace, A.; Cavacini, L.; Choudhary, A. K.; Proulx, M. K.; Sundling, C.; Källenius, G.; Reljic, R.; Ernst, J. D.; Casadevall, A.; Locht, C.; Pinter, A.; Sassetti, C. M.; Bryson, B. D.; Fortune, S. M.; Alter, G.
10.1101/2024.10.07.617070 — immunology — Posted on 2024-10-11
3852 Fronto-motor circuits linked to subclinical apathy
Derosiere, G.; Vassiliadis, P.; Dricot, L.; Dessain, Q.; Delinte, N.; Zenon, A.; Duque, J.
10.1101/2024.10.07.616861 — neuroscience — Posted on 2024-10-11
3854 Controlling heterologous protein synthesis through a plant RNA ThermoSwitch
Lastovka, F.; Peyret, H.; Thomas, S. E.; Lomonossoff, G. P.; Chung, B. Y.
10.1101/2024.10.07.616989 — plant biology — Posted on 2024-10-11
3856 Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research
Sandulache, V.; Perez-Bello, D. C.; Yadollahi, P.; Castro, P.; Frederick, A.; Frederick, A.; Osman, R.; Essien, F.; Yebra, I.; Hamlin, A.; Ow, T.; Skinner, H.
10.1101/2024.10.10.617597 — cancer biology — Posted on 2024-10-11
3860 Can We Ever Develop an Ideal RNA Force Field? Lessons Learned from Simulations of UUCG RNA Tetraloop and Other Systems.
Mlynsky, V.; Kuehrova, P.; Pykal, M.; Krepl, M.; Stadlbauer, P.; Otyepka, M.; Banas, P.; Sponer, J.
10.1101/2024.10.08.617195 — biophysics — Posted on 2024-10-11
3862 Computational Insights into Membrane Disruption by Cell-Penetrating Peptides
Catalina-Hernandez, E.; Aguilella-Arzo, M.; Peralvarez-Marin, A.; Lopez-Martin, M.
10.1101/2024.10.09.617374 — biophysics — Posted on 2024-10-11
3866 In situ crystalline structure of the Eosinophil major basic protein-1
Yang, J. E.; Mitchell, J. M.; Bingman, C. A.; Mosher, D. F.; Wright, E. R.
10.1101/2024.10.09.617336 — biophysics — Posted on 2024-10-11
3867 A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA
Aretz, J.; Jeyasankar, G.; Salerno-Kochan, A.; Thomsen, M.; Thieulin-Pardo, G.; Haque, T.; Monteagudo, E.; Felsenfeld, D.; Finley, M.; Vogt, T. F.; Boudet, J.; Prasad, B. C.
10.1101/2024.10.09.617442 — biophysics — Posted on 2024-10-11
3874 Data-driven evaluation of suitable immunogens for improved antibody selection
Waury, K.; Kvartsberg, H.; Zetterberg, H.; Blennow, K.; Teunissen, C. E.; Abeln, S.
10.1101/2024.10.07.617016 — bioinformatics — Posted on 2024-10-11
3879 A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer
Munoz-Erazo, L.; Park, S. M.; Lin, S.; Chen, C.-J. J.; Zhou, L. Y. Y.; Rhodes, J. L.; Jeon, T.; Fenton, S.; McCall, J. L.; Kemp, R. A.; Dunbar, R.
10.1101/2024.10.06.616904 — cancer biology — Posted on 2024-10-11
3886 Optimal Prescriptive Treatments for Ovarian Cancer with Genetic Data
Mertzios, A.; Gjika, M.; Xu, X.; Guha, S.; Bardhan, N. M.; Kumar, S.; Belcher, A.; Perakis, G.
10.1101/2024.10.08.617334 — cancer biology — Posted on 2024-10-11
3887 Targeting Heterochromatin Eliminates Malignant Stem Cells in Chronic Myelomonocytic Leukemia Through Reactivation of Retroelements and Innate Immune pathways
Hidaoui, D.; Porquet, A.; Chelbi, R.; Bohm, M.; Polizou, A.; Alcazer, V.; Depil, S.; Imanci, A.; Morabito, M.; Renneville, A.; Selimoglu-Buet, D.; Thepot, S.; Itzykson, R.; Laplane, L.; Droin, N.; Trompouki, E.; Elvira-Matelot, E.; Solary, E.; PORTEU, F.
10.1101/2024.02.02.578583 — cancer biology — Posted on 2024-10-11
3888 Inhibition of Androgen Receptor Exposes Replication Stress Vulnerability in Prostate Cancer
Williams, C. S.; Li, X.; Jang, H.; Anand, J. R.; Lim, W. Y.; Lee, H.; Parks, J.; Zhang, X.; Xie, J.; Zhao, J.; Wu, D.; Armstrong, A. J.; Bowser, J. L.; Zou, L.; Hong, J.; Somarelli, J. A.; Vaziri, C.; Zhou, P.
10.1101/2024.10.08.617102 — cancer biology — Posted on 2024-10-11
3889 Limitations of the radiotheranostic concept in neuroendocrine tumors due to lineage-dependent somatostatin receptor expression on hematopoietic stem and progenitor cells
Nguyen, N.; Min, Y.; Riviere, J.; van der Garde, M.; Ghosh, S.; Bartos, L.; Brendel, M.; Bassermann, F.; Azhdarinia, A.; Weber, W. A.; Goetze, K.; Kossatz, S.
10.1101/2024.10.07.615865 — cancer biology — Posted on 2024-10-11
3890 Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma
Sun, N.-Y.; Kumar, S.; Kim, Y. S.; Varghese, D.; Mendoza, A.; Nguyen, R.; Okada, R.; Reilly, K.; Widemann, B.; Pommier, Y.; Elloumi, F.; Dhall, A.; Patel, M.; Aber, E.; Contreras-Burrola, C.; Kaplan, R.; Martinez, D.; Pogoriler, J.; Hamilton, A. K.; Diskin, S. J.; Maris, J. M.; Robey, R. W.; Gottesman, M. M.; Del Rivero, J.; Roper, N.
10.1101/2024.10.09.617077 — cancer biology — Posted on 2024-10-11
3893 Full-length Cryptochrome 1 in the outer segments of the retinal blue cone photoreceptors in humans and great apes suggests a role beyond transcriptional repression
Bartoelke, R.; Niessner, C.; Reinhard, K.; Wolfrum, U.; Meimann, S.; Bolte, P.; Feederle, R.; Mouritsen, H.; Dedek, K.; Peichl, L.; Winklhofer, M.
10.1101/2024.10.10.617617 — cell biology — Posted on 2024-10-11
3894 H2AK119ub dynamics controls hair follicle stem cell quiescence
Flora, P.; Li, M.-Y.; Zhou, Y.; Mercedes, M.; Zheng, X. Y.; Galbo, P. M.; Zheng, D.; Ezhkova, E.
10.1101/2024.10.10.617646 — cell biology — Posted on 2024-10-11
3895 Mitochondrial dysfunction: unraveling the elusive biology behind anti-TNF response during ulcerative colitis
Kioroglou, D.; Pena-Cearra, A.; Corraliza, A.; Seoane, I.; Castelo, J.; Panes, J.; Gomez-Irwin, L.; Lago, I. R.; Ortiz de Zarate, J.; Fuertes, M.; Martin-Ruiz, I.; Gonzalez, M.; Aransay, A. M.; Salas, A.; Rodriguez, H.; Anguita, J.; Abecia, L.; Marigorta, U.
10.1101/2024.06.18.599496 — immunology — Posted on 2024-10-11
3897 Catabolism of extracellular glutathione supplies amino acids to support tumor growth
Hecht, F.; Zocchi, M.; Tuttle, E. T.; Ward, N. P.; Smith, B.; Kang, Y. P.; Cazarin, J.; Soares, Z. G.; Ozgurses, M. E.; Zhao, H.; Sheehan, C.; Alimohammadi, F.; Munger, L. D.; Trivedi, D.; Asantewaa, G.; Blick-Nitko, S. K.; Zoeller, J. J.; Chen, Y.; Vasiliou, V.; Turner, B. M.; Muir, A.; Coloff, J. L.; Munger, J.; DeNicola, G. M.; Harris, I. S.
10.1101/2024.10.10.617667 — cancer biology — Posted on 2024-10-11
3898 Mapping the Spatial Proteome of Leukemia Cells Undergoing Fludarabine Treatment
Globisch, M. A.; Gezelius, H.; Enblad, A. P.; Lundmark, A.; Lysenkova Wiklander, M. A.; Krali, O.; Aberg, M.; Harila, A.; Raine, A.; Andersson, C.; Nordlund, J.
10.1101/2024.10.10.617576 — cancer biology — Posted on 2024-10-11
3900 An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer
Dalessi, T.; Valenta, T.; Moro, G.; Brügger, M. D.; Meijs, A.; Szczerba, B. M.; Brunner, T.; Lampart, S.; Nater, M.; van den Broek, M.; Platt, R. J.; Scharl, M.; Fazilaty, H.
10.1101/2024.10.08.617191 — cancer biology — Posted on 2024-10-11
3903 Mining the Proteome of Human Ovarian Cancer Extracellular Vesicles Using Thermolysin Proteolysis
Cooper, T. T.; Liu, J.; Bilyk, O.; Jewer, M.; AOCS Study Group, ; Steed, H.; Fu, Y.; Postovit, L.-M.; Lajoie, G. A.
10.1101/2024.10.10.617562 — cancer biology — Posted on 2024-10-11
3904 Allosteric degraders induce CRL5ASB8 mediated degradation of XPO1
Hudman-Wing, C. E.; Fung, H. Y. J.; Cagatay, T.; Kwanten, B.; Niesman, A. B.; Gharghabi, M.; Permentier, B.; Shakya, B.; Shacham, S.; Landesman, Y.; Lapalombella, R.; Daelemans, D.; Chook, Y. M.
10.1101/2024.10.07.617049 — cancer biology — Posted on 2024-10-11
3905 Functional screen for mediators of onco-mRNA translation specificity
Kovalski, J. R.; Sarioglu, G.; Subramanyam, V.; Hernandez, G.; Rademaker, G.; Oses-Prieto, J. A.; Slota, M.; Mohan, N.; Yiakis, K.; Liu, I.; Wen, K. W.; Kim, G. E.; Miglani, S.; Burlingame, A.; Goodarzi, H.; Perera, R. M.; Ruggero, D.
10.1101/2024.10.10.617637 — cancer biology — Posted on 2024-10-11
3907 A CXCR4 partial agonist improves immunotherapy by targeting polymorphonuclear myeloid-derived suppressor cells and cancer-driven granulopoiesis
Qian, J.; Ma, C.; Waterbury, Q. T.; Zhi, X.; Moon, C. S.; Tu, R.; Kobayashi, H.; Wu, F.; Zheng, B.; Zeng, Y.; Zheng, H.; Ochiai, Y.; White, R. A.; Harle, D. W.; LaBella, J. S.; Zamechek, L. B.; Hu, L. Z.; Moy, R. H.; Han, A. S.; Daugherty, B.; Lederman, S.; WANG, T. C.
10.1101/2024.10.09.617228 — cancer biology — Posted on 2024-10-11
3909 Translocations can drive expression changes of multiple genes in regulons covering entire chromosome arms
Oncins, A.; Zaurin, R.; Toukabri, H.; Quililan, K.; Hernandez Mora, J. R.; Karpinska, M. A.; Wernersson, E.; Smith, A.; Bianchi, A.; Albinati, L.; Rivero, A.; Serra, F.; Gomez, R.; Lopez, C.; Bea, S.; Halidi, N.; Valencia, A.; Bienko, M.; Oudelaar, A. M.; Beekman, R.
10.1101/2024.10.07.616925 — cancer biology — Posted on 2024-10-11
3911 Targetable Treatment Resistance in Thyroid Cancer with Clonal Hematopoiesis
Tiedje, V.; Vela, P. S.; Yang, J. L.; Untch, B. R.; Boucai, L.; Stonestrom, A. J.; Costa, A. B.; Exposito, S. F.; Srivastava, A.; Kerpelev, M.; Greenberg, J.; Wereski, M.; Kulick, A.; Chen, K.; Qin, T.; Im, S.-Y.; Krishnan, A.; Benitez, A. R. M.; Pluvinet, R.; Sahin, M.; Menghrajani, K.; Krishnamoorthy, G. P.; De Stanchina, E.; Zehir, A.; Satija, R.; Knauf, J.; Bowman, R.; Esteller, M.; Devlin, S. M.; Berger, M.; Koche, R.; Fagin, J. A.; Levine, R.
10.1101/2024.10.10.617685 — cancer biology — Posted on 2024-10-11
3912 Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research
Sandulache, V.; Perez-Bello, D. C.; Yadollahi, P.; Castro, P.; Frederick, A.; Frederick, A.; Osman, R.; Essien, F.; Yebra, I.; Hamlin, A.; Ow, T.; Skinner, H.
10.1101/2024.10.10.617597 — cancer biology — Posted on 2024-10-11
3916 An atypical E3 ligase safeguards the ribosome during nutrient stress
Douglas, T.; Zhang, J.; Wu, Z.; Abdallah, K.; McReynolds, M.; Gilbert, W. V.; Iwai, K.; Peng, J.; Young, L. H.; Crews, C. M.
10.1101/2024.10.10.617692 — cell biology — Posted on 2024-10-11
3917 cGAS deficient mice display premature aging associated with de-repression of LINE1 elements and inflammation
Martinez, J. C.; Morandini, F.; Fitzgibbons, L.; Sieczkiewicz, N.; Bae, S. J.; Meadow, M. E.; Hillpot, E.; Cutting, J.; Paige, V.; Biashad, S. A.; Simon, M.; Sedivy, J.; Seluanov, A.; Gorbunova, V.
10.1101/2024.10.10.617645 — cell biology — Posted on 2024-10-11
3918 The small GTPase Ran defines Nuclear Pore Complex asymmetry
Sachweh, J.; Börmel, M.; Klumpe, S.; Becker, A.; Taniguchi, R.; Kubanska, M. A.; Pintschovius, V.; Kaindl, E.; Plitzko, J. M.; Wilfling, F.; Beck, M.; Hampoelz, B.
10.1101/2024.10.10.617378 — cell biology — Posted on 2024-10-11
3919 Dissecting compounded hepatocyte injury in a model of MASLD progression from human induced pluripotent stem cells
Weihs, J.; Baldo, F.; Cardinali, A.; Youssef, G.; Ludwik, K.; Stachelscheid, H.; Haep, N.; Tang, P.; Sauer, I.; Kumar, P.; Engelmann, C.; Quach, S.; Bufler, P.; Han, N.; Rezvani, M.
10.1101/2024.10.10.617610 — cell biology — Posted on 2024-10-11
3920 A large reverse-genetic screen identifies numerous regulators of testis nascent myotube collective cell migration and collective organ sculpting
Bischoff, M. C.; Norton, J. E.; Munguia, E. A.; Gurley, N. J.; Clark, S. E.; Korankye, R.; Gyabaah, E. A.; Encarnacion, T.; Serody, C. J.; Jones, C. D.; Peifer, M.
10.1101/2024.10.10.617659 — cell biology — Posted on 2024-10-11
3923 The role of GPR87 in Pulmonary Fibrosis
Khoury, J.; Ahangari, F.; Adams, T.; Justet, A.; Manning, E.; McDonough, J. E.; Barnthaler, T.; Anderson, S.; Nikola, F.; Beermann, M. L.; Gomez, J. L.; Kaminski, N.
10.1101/2024.10.10.617569 — cell biology — Posted on 2024-10-11
3924 Functional Impact of Nth-like DNA glycosylase on Mitochondrial Dynamics
Hubers, L. A.; Sjetne, A. M.; Luna, L.; Wagbo, A. M.; Lefol, Y.; Naranjo Galindo, F. J.; Berg-Eriksen, A. K.; Visnes, T.; Nilsen, H.; Montaldo, N. P.
10.1101/2024.10.10.617535 — cell biology — Posted on 2024-10-11
3927 SynDRep: A Knowledge Graph-Enhanced Tool based on Synergistic Partner Prediction for Drug Repurposing
Shalaby, K. S.; Rao, S. G.; Schultz, B.; Hofmann-Apitius, M.; Tom Kodamullil, A.; Bharadhwaj, V. S.
10.1101/2024.08.13.607713 — bioinformatics — Posted on 2024-10-11
3931 Animal acoustic communication maintains a universal optimum rhythm
Piette, T.; Cathcart, C.; Barbieri, C.; Martin Ming, K.; Grandjean, D.; Bickel, B.; Deaux, E.; Giraud, A.-L.
10.1101/2024.10.07.616955 — animal behavior and cognition — Posted on 2024-10-11
3932 A molecular switch orchestrates the nuclear export of human messenger RNA
Hohmann, U.; Graf, M.; Schellhaas, U.; Pacheco-Fiallos, B.; Fin, L.; Riabov-Bassat, D.; Pühringer, T.; Szalay, M.-F.; Tirian, L.; Handler, D.; Brennecke, J.; Plaschka, C.
10.1101/2024.03.24.586400 — molecular biology — Posted on 2024-10-11
3934 Protein Surface Chemistry Encodes an Adaptive Tolerance to Desiccation
Romero-Perez, P. S.; Moran, H. M.; Horani, A.; Truong, A.; Manriquez-Sandoval, E.; Ramirez, J. F.; Martinez, A.; Golub, E.; Hunter, K.; Lotthammer, J. M.; Emenecker, R. J.; Boothby, T. C.; Holehouse, A. S.; Fried, S. D.; Sukenik, S.
10.1101/2024.07.28.604841 — biophysics — Posted on 2024-10-11
3938 Heterogeneous and higher-order cortical connectivity undergirds efficient, robust and reliable neural codes
Egas Santander, D.; Pokorny, C.; Ecker, A.; Lazovskis, J.; Santoro, M.; Smith, J. P.; Hess, K.; Levi, R.; Reimann, M. W.
10.1101/2024.03.15.585196 — neuroscience — Posted on 2024-10-11
3939 Exploiting correlations across trials and behavioral sessions to improve neural decoding
Zhang, Y.; Lyu, H.; Hurwitz, C.; Wang, S.; Findling, C. L.; Hubert, F.; Pouget, A.; International Brain Laboratory, ; Varol, E.; Paninski, L.
10.1101/2024.09.14.613047 — neuroscience — Posted on 2024-10-11
3940 The heartbeat-evoked potential in young and older adults during attention orienting
Aprile, F.; Simoes, M.; Henriques, J.; de Carvalho, P.; Castelo-Branco, M.; Sel, A.; Ribeiro, M. J.
10.1101/2024.01.31.578137 — neuroscience — Posted on 2024-10-11
3941 Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction
Hwang, S.-Y.; Jeon, K.-H.; Lee, H.-J.; Moon, I.; Jung, S.; Kim, S.-A.; Jo, H.; Park, S.; Ahn, M.; Kwak, S.-Y.; Na, Y.; Kwon, Y.
10.1101/2024.03.01.583029 — pharmacology and toxicology — Posted on 2024-10-11
3943 Enhancing Cytoplasmic Expression of Exogenous mRNA through Dynamic Mechanical Stimulation
Chen, J.; Patel, A.; Mir, M.; Hudock, M.; Pinezich, M.; Guenthart, B.; Bacchetta, M.; Vunjak-Novakovic, G.; Kim, J.
10.1101/2024.06.19.599708 — bioengineering — Posted on 2024-10-10
3944 Potent LILRB1 D1D2-containing antibodies inhibit RIFIN-mediated immune evasions
Wang, Y.; Tang, H.; Wang, W.; Li, M.; Zhu, C.; Dai, H.; Zhao, H.; Wu, B.; Wang, J.
10.1101/2024.08.08.607148 — biochemistry — Posted on 2024-10-11
3945 Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing
Hazelbaker, D. Z.; Mehta, J. B.; McGinnis, C.; Santesmasses, D.; Bara, A. M.; Liang, X.; Biondi, T.; Fennell, T.; Homer, N.; Estes, B.; Xie, J.; Norouzi, D.; Molugu, K.; Amunugama, R.; Luo, C.; Amin, P.; Shi, X.; Cochrane, J.; Kumar, S.; Wang, J.; Bakalar, M. H.; Finn, J. D.; O'Connell, D. J.
10.1101/2024.08.23.609471 — genomics — Posted on 2024-10-11
3948 Piximi - An Images to Discovery web tool for bioimages and beyond
Moser, L. M.; Gogoberidze, N.; Papaleo, A.; Lucas, A.; Dao, D.; Friedrich, C. A.; Paavolainen, L.; Molnar, C.; Stirling, D. R.; Hung, J.; Wang, R.; Tromans-Coia, C.; Li, B.; Evans, E. L.; Eliceiri, K. W.; Horvath, P.; Carpenter, A. E.; Cimini, B. A.
10.1101/2024.06.03.597232 — cell biology — Posted on 2024-10-10
3950 SpinalTRAQ: A novel volumetric cervical spinal cord atlas identifies the corticospinal tract synaptic projectome in healthy and post-stroke mice
Poinsatte, K.; Kenwood, M.; Betz, D.; Nawaby, A.; Ajay, A. D.; Xu, W.; Plautz, E. J.; Kong, X.; Ramirez, D. M. O.; Goldberg, M. P.
10.1101/2024.08.23.609434 — neuroscience — Posted on 2024-10-10
3951 GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
Sivadasan Bindu, D.; Savage, J. T.; Brose, N.; Bradley, L.; Dimond, K.; Tan, C. X.; Eroglu, C.
10.1101/2023.01.17.524433 — neuroscience — Posted on 2024-10-11
3954 Natural disturbances and connectivity shape the seasonal variability of aquatic macroinvertebrate communities across Europe
Chalmandrier, L.; Cunillera-Montcusi, D.; Lopez-Rojo, n.; Canedo-Arguelles, M.; Csabai, Z.; Foulquier, A.; Jabot, F.; Milisa, M.; Mykra, H.; Paril, P.; Pernecker, B.; Polovic, L.; Sarremejane, R.; Snare, H.; Soria, M.; Datry, T.; Bonada, N.; Munoz, F.
10.1101/2024.10.09.617360 — ecology — Posted on 2024-10-10
3957 Evidence of opportunistic blood feeding in the parasitic nematode Heligmosomoides bakeri
Szabo, E. K.; Wasmuth, J. D.; Coria, A. L.; Rich, K.; Liu, H.; Finney, C. A.
10.1101/2024.10.09.617485 — zoology — Posted on 2024-10-10
3961 Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation
Spath, E.; Schuler, S. C.; Heinze, I.; Dau, T. T. D.; Minetti, A.; Hofmann, M.; von Maltzahn, J.; Ori, A.
10.1101/2024.03.29.587321 — cell biology — Posted on 2024-10-10
3963 Sanfetrinem, an oral beta-lactam antibiotic repurposed for the treatment of tuberculosis
Ramon-Garcia, S.; Gonzalez del Rio, R.; Arenaz-Callao, M. P.; Boshoff, H. I. M.; Rullas-Trincado, J.; Anca, S.; Cacho Izquierdo, M.; Porras de Francisco, E.; Perez Herran, E.; Santos-Villarejo, A.; Mendoza-Losana, A.; Ferrer-Bazaga, S.; Thompson, C. J.; Barros-Aguirre, D.; Bates, R. H.
10.1101/2024.10.10.617558 — microbiology — Posted on 2024-10-10
3967 Torsional Mechanics of Circular DNA
Singh, G.; Hong, Y.; Inman, J. T.; Sethna, J. P.; Wang, M. D.
10.1101/2024.10.08.617281 — biophysics — Posted on 2024-10-10
3968 Structural basis of SIRT7 nucleosome engagement and substrate specificity
Moreno Yruela, C.; Ekundayo, B.; Foteva, P. N.; Calvino Sanles, E.; Ni, D.; Stahlberg, H.; Fierz, B.
10.1101/2024.10.10.617549 — biophysics — Posted on 2024-10-10
3969 DNA Polymerase Locks Replication Fork Under Stress
Jia, X.; Inman, J. T.; Singh, A.; Patel, S. S.; Wang, M. D.
10.1101/2024.10.09.617451 — biophysics — Posted on 2024-10-10
3970 2.6-A resolution cryo-EM structure of a class Ia ribonucleotide reductase trapped with mechanism-based inhibitor N3CDP
Westmoreland, D. E.; Feliciano, P. R.; Kang, G.; Cui, C.; Kim, A.; Stubbe, J.; Nocera, D. G.; Drennan, C. L.
10.1101/2024.10.09.617422 — biophysics — Posted on 2024-10-10
3972 Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis
Brothwell, M. J.; Cao, G.; Maschek, J. A.; Poss, A. M.; Peterlin, A. D.; Wang, L.; Baker, T. B.; Shahtout, J. L.; Siripoksup, P.; Pearce, Q. J.; Johnson, J. M.; Finger, F. M.; Prola, A.; Pellizzari, S. A.; Hale, G. L.; Manuel, A. M.; Watanabe, S.; Miranda, E. R.; Affolter, K. E.; Tippetts, T. S.; Nikolova, L. S.; Choi, R. H.; Decker, S. T.; Patil, M.; Catrow, J. L.; Holland, W. L.; Nowinski, S. M.; Lark, D. S.; Fisher-Wellman, K. H.; Mimche, P. N.; Evason, K. J.; Cox, J. E.; Summers, S. A.; Gerhart-Hines, Z.; Funai, K.
10.1101/2024.10.10.617517 — biochemistry — Posted on 2024-10-10
3973 Discovery of new and variant Potyviruses in Asparagales plants from a Dutch urban botanic garden
Dekker, R. J.; Rauwerda, H.; de Leeuw, W. C.; van Olst, M.; Ensink, W. A.; van Leeuwen, S.; Meijs, C.; Baksi, M. M. M.; Breit, T. M.; Jonker, M. J.
10.1101/2024.10.09.617369 — genomics — Posted on 2024-10-10
3974 Genomic and epigenomic maps of mouse centromeres and pericentromeres
Chaudhry, G.; Chen, J.; Snipes, L.; Bahl, S.; Packiaraj, J.; Lin, X.; Thakur, J.
10.1101/2024.10.09.617447 — genomics — Posted on 2024-10-10
3975 Mapping multiple RNA modifications simultaneously by proximity barcode sequencing
Sendinc, E.; Yu, H.; Hwang Fu, Y. H.; Santos, J.; Johnson, Z.; Kirstein, J. R.; Niu, J.; Chabot, M. B.; Cantu, V. A.; Dzakula, Z.; Lam, Q.; Anmangandla, A.; Burcham, T. S.; Davis, E. M.; Miles, Z. D.; Price, A. D.; Purse, B. W.; Gregory, R. I.; Stengel, G.
10.1101/2024.10.09.617509 — genomics — Posted on 2024-10-10
3976 CRISPR tiling deletion screens reveal functional enhancers of neuropsychiatric risk genes and allelic compensation effects (ACE) on transcription
Ren, X.; Zheng, L.; Maliskova, L.; Tam, T. W.; Sun, Y.; Liu, H.; Lee, J.; Takagi, M. A.; Li, B.; Ren, B.; Wang, W.; Shen, Y.
10.1101/2024.10.08.616922 — genetics — Posted on 2024-10-10
3978 Reporter CRISPR screens decipher cis- and trans-regulatory principles at the Xist locus
Schwaemmle, T.; Noviello, G.; Kanata, E.; Froehlich, J. J.; Bothe, M.; Altay, A.; Scouarnec, J.; Feng, V.-Y.; Vingron, M.; Schulz, E. G.
10.1101/2024.10.08.617282 — genetics — Posted on 2024-10-10
3979 De novo rates of a Trypanosoma-resistant mutation in two human populations
Melamed, D.; Shemer, R.; Bolotin, E.; Yakass, M. B.; Fink-Barkai, D.; Hiadzi, E. K.; Skorecki, K. L.; Livnat, A.
10.1101/2024.10.10.617206 — evolutionary biology — Posted on 2024-10-10
3980 CCG interruptions are unstable and hypermethylated in DM1 patients
Lameiras, S.; Lampraki, E. M.; Kilburn, D.; Alaeitabar, T.; Jamail, I.; Servant, N.; Baulande, S.; Kingan, S. B.; Holt, S.; Gaysinskaya, V.; Brandine, G. D. S.; Stucki, D.; Stojkovic, T.; Bassez, G.; Furling, D.; Gourdon, G.; Tome, S.
10.1101/2024.10.10.617614 — molecular biology — Posted on 2024-10-10
3982 MANGIFERIN AS A POTENTIAL INHIBITOR OF TRANSTHYRETIN FIBRILOGENESIS
Grudinina, N.; Petukhov, M. G.; Shaldzhyan, A. A.; Zabrodskaya, Y. A.; Gavrilova, N. V.; Morozkina, S. N.; Egorov, V. V.
10.1101/2024.10.09.617482 — molecular biology — Posted on 2024-10-10
3987 Semi-automated workflow for high-throughput Agrobacterium-mediated plant transformation
Annese, D.; Romani, F.; Grandellis, C.; Ives, L.; Frangedakis, E.; Buson, F. X.; Molloy, J. C.; Haseloff, J.
10.1101/2024.10.09.617252 — synthetic biology — Posted on 2024-10-10
3989 Improving HEK293-based AAV-production using GSMMs, and a multi-omics approach
Zehetner, L.; Szeliova, D.; Kraus, B.; Hernandez Bort, J.; Zanghellini, J.
10.1101/2024.10.10.617556 — bioengineering — Posted on 2024-10-10
3991 Chemical circularization of in vitro transcribed RNA opens new avenues for circular mRNA design
Mamot, A.; Wasinska-Kalwa, M.; Czubak, K.; Frankowska, K.; Spiewla, T.; Warminski, M.; Nowis, D.; Golab, J.; Kowalska, J.; Jemielity, J.
10.1101/2024.10.10.617555 — biochemistry — Posted on 2024-10-10
3994 Endogenous tagging of Munc13-1 with a SNAP tag as a tool for monitoring synapse nanoarchitecture
Kowald, M.; Bachollet, S. P. J. T.; Benseler, F.; Steinecker, M.; Kaushik, S.; Soykan, T.; Sun, S.; Birke, R.; Ilic, D.; Brose, N.; Hoernberg, H.; Lehmann, M.; Rizzoli, S.; Broichhagen, J.; Lipstein, N.
10.1101/2024.10.08.617143 — neuroscience — Posted on 2024-10-10
3997 The mineralization of osteonal cement line depends on where the osteon is formed
Cantamessa, A.; Blouin, S.; Rummler, M.; Berzlanovich, A.; Weinkamer, R.; Hartmann, M. A.; Ruffoni, D.
10.1101/2024.10.06.616843 — bioengineering — Posted on 2024-10-10
4000 Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics
VanBelzen, J.; Sakelaris, B.; Brickner, D. G.; Marcou, N.; Riecke, H.; Mangan, N.; Brickner, J. H.
10.1101/2024.07.08.602535 — molecular biology — Posted on 2024-10-10
4005 Olfaction in Tephritidae: a balance between detection and discrimination
Ramiaranjatovo, G.; Charlery de la Masseliere, M.; Dekker, T.; Duyck, P.-F.; Larsson Herrera, S.; Reynaud, B.; Jacob, V.
10.1101/2024.03.14.584788 — ecology — Posted on 2024-10-10
4007 Non-equilibrium remodelling of collagen-IV networks in silico
Meadowcroft, B.; Sorichetti, V.; Ratajczyk, E.; Khalilgharibi, N.; Mao, Y.; Palaia, I.; Saric, A.
10.1101/2024.10.10.617412 — biophysics — Posted on 2024-10-10
4010 Deep-sea fish reveal alternative pathway for vertebrate visual development
Fogg, L. G.; Isari, S.; Barnes, J. E.; Patel, J. S.; Marshall, J.; Salzburger, W.; Cortesi, F.; de Busserolles, F.
10.1101/2024.10.10.617579 — evolutionary biology — Posted on 2024-10-10
4019 Empirically establishing drug exposure records directly from untargeted metabolomics data
Zhao, H. N.; Kvitne, K. E.; Brungs, C.; Mohan, S.; Charron-Lamoureux, V.; Bittremieux, W.; Tang, R.; Schmid, R.; Lamichhane, S.; El Abiead, Y.; Andalibi, M. S.; Mannochio-Russo, H.; Ambre, M.; Avalon, N. E.; Bryant, M.; Caraballo-Rodriguez, A. M.; Maya, M. C.; Chin, L.; Ellis, R. J.; Franklin, D.; Girod, S.; Gomes, P. W. P.; Hansen, L.; Heaton, R.; Iudicello, J. E.; Jarmusch, A. K.; Khatib, L.; Letendre, S.; Magyari, S.; McDonald, D.; Mohanty, I.; Cumsille, A.; Moore, D. J.; Rajkumar, P.; Ross, D. H.; Sapre, H.; Shahneh, M. R. Z.; Thomas, S. P.; Tribelhorn, C.; Tubb, H. M.; Walker, C.; Wang, C
10.1101/2024.10.07.617109 — bioinformatics — Posted on 2024-10-10
4025 Unique belowground ecological strategies of subtropical and tropical plant species expand the root trait space
Guerrero Ramirez, N. R.; Weemstra, M.; Addo-Danso, S. D.; Andersen, K.; Arnaud, M.; Cordeiro, A. L.; Cusack, D. F.; Kotowska, M. M.; Lee, M. Y.; Leroy, C.; Lugli, L. F.; Pierick, K.; Smith-Martin, C. M.; Toro, L.; Umana, M. N.; Valverde-Barrantes, O. J.; Wong, M.; Fortunel, C.
10.1101/2024.10.06.616893 — ecology — Posted on 2024-10-10
4026 A novel human pluripotent stem cell-based gene activation system identifies IGFBP2 as a mediator in the production of hematopoietic progenitors in vitro
Petazzi, P.; Ventura, T.; Luongo, F. P.; McClafferty, H.; May, A.; Taylor, H. A.; Shipston, M.; Romano, N.; Forrester, L.; Menendez, P.; Fidanza, A.
10.1101/2024.01.14.575573 — cell biology — Posted on 2024-10-10
4029 assessPool: a fexible pipeline for population genomic analyses of pooled sequencing data
Freel, E. B.; Conklin, E. E.; Kraft, D. W.; Whitney, J. L.; Knapp, I. S.; Forsman, Z. H.; Toonen, R. J.
10.1101/2024.10.09.617480 — bioinformatics — Posted on 2024-10-10
4030 Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections
Lydon, E.; Osborne, C. M.; Wagner, B. D.; Ambroggio, L.; Harris, J. K.; Reeder, R. W.; Carpenter, T. C.; Maddux, A. B.; Leroue, M. K.; Yehya, N.; DeRisi, J. L.; Hall, M. W.; Zuppa, A.; Carcillo, J. A.; Meert, K.; Sapru, A.; Pollack, M. M.; McQuillen, P.; Notterman, D.; Langelier, C. R.; Mourani, P. M.
10.1101/2024.10.08.617294 — immunology — Posted on 2024-10-10
4033 Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases
Huang, S.-W.; Lai, Y.-G.; Liao, H.-T.; Chang, C.-L.; Ma, R.-Y.; Chen, Y.-H.; Liou, Y.-H.; Wu, Z.-Q.; Wu, Y.-C.; Liu, K.-J.; Huang, Y.-T.; Yang, J.-L.; Dai, M.-S.; Liao, N.-S.
10.1101/2024.05.03.592329 — immunology — Posted on 2024-10-10
4034 Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex
Bibineyshvili, Y.; Vajtay, T. J.; Salsabilian, S.; Fliss, N.; Suvarnakar, A.; Fang, J.; Teng, S.; Alder, J.; Najafizadeh, L.; Margolis, D. J.
10.1101/2024.04.24.590835 — neuroscience — Posted on 2024-10-10
4035 Targeting circadian transcriptional programs in triple negative breast cancer through a cis-regulatory mechanism
Pan, Y.; Chiu, T.-P.; Zhou, L.; Chan, P.; Kuo, T. T.; Battaglin, F.; Soni, S.; Lenz, H.-J.; Jayachandran, P.; Li, J. J.; Mumenthaler, S.; Rohs, R.; Roussos Torres, E.; Kay, S. A.
10.1101/2024.04.26.590360 — cancer biology — Posted on 2024-10-10
4036 Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping
Fernandez-Mateos, J.; Milite, S.; Oliveira, E.; Vlachogiannis, G.; Chen, B.; Yara, E.; Cresswell, G. D.; James, C.; Patruno, L.; Ascolani, G.; Acar, A.; Heide, T.; Spiteri, I.; Graudenzi, A.; Caravagna, G.; Graham, T.; Magnani, L.; Valeri, N.; Sottoriva, A.
10.1101/2023.11.15.567140 — cancer biology — Posted on 2024-10-10
4037 Automated Integration of Multi-Slice Spatial Transcriptomics Data in 2D and 3D
Bienroth, D.; Charitakis, N.; Wong, D.; Jaeger-Honz, S.; Garkov, D.; Watt, K. I.; Stolper, J.; Chambers-Smith, H.; MacGregor, D.; Christiansen, B.; Piers, A. T.; Porrello, E. R.; Elliot, D.; Klein, K.; Nim, H. T.; Schreiber, F.; Ramialison, M.
10.1101/2023.03.31.535025 — bioinformatics — Posted on 2024-10-10
4038 Multicomponent Thiolactone-Based Ionizable Lipid Screening Platform for an Efficient and Tunable mRNA Delivery to the Lungs
Pena, A.; Heredero, J.; Blandin, B.; Mata, E.; De Miguel, D.; Toro, A.; Alejo, T.; Casabona, D.; Lopez, A.; Gallego-Lleyda, A.; Perez-Herran, E.; Martinez-Olivan, J.; Gimenez-Warren, J.
10.1101/2024.10.09.617396 — biochemistry — Posted on 2024-10-10
4041 Enhanced RNA-targeting CRISPR-Cas technology in zebrafish
Moreno-Sanchez, I.; Hernandez-Huertas, L.; Nahon-Cano, D.; Gomez-Marin, C.; Martinez-Garcia, P. M.; Tomas-Gallardo, L.; da Silva Pescador, G.; Kushawah, G.; Diaz-Moscoso, A.; Cano-Ruiz, A.; Walker, J. A.; Munoz, M. J.; Holden, K.; Galceran, J.; Nieto, M. A.; Bazzini, A.; Moreno-Mateos, M. A.
10.1101/2024.10.08.617220 — developmental biology — Posted on 2024-10-10
4042 Loss of 18q alters TGFβ signalling affecting anteroposterior neuroectodermal fate in human embryonic stem cells
Lei, Y.; Duong, M. C.; Krivec, N.; Janssens, C.; Regin, M.; Huyghebaert, A.; Couvreu De Deckersberg, E.; Sermon, K. D.; Al Delbany, D.; Spits, C.
10.1101/2024.10.09.617397 — cell biology — Posted on 2024-10-10
4043 Hidden evolutionary constraints dictate the retention of coronavirus accessory genes
Goldstein, S. A.; Feeley, T. M.; Babler, K. M.; Hilbert, Z. A.; Downhour, D. M.; Moshiri, N.; Elde, N. C.
10.1101/2023.10.12.561935 — evolutionary biology — Posted on 2024-10-09
4044 Loss of killifish cGAS/STING function attenuates cellular senescence and age-related signatures but does not extend organismal life span
Ballhysa, E.; Ripa, R.; Hochhard, N.; Nguyen, T. T. M.; Brazzell, J.; Ferreri, B.; Hoffmann, E.; Steiner, J. D.; Antebi, A.
10.1101/2024.10.08.617203 — developmental biology — Posted on 2024-10-10
4045 EPHA2 Regulates SOX2 during Esophageal Development
Li, T.; Mitani, Y.; Cruz-Acuna, R.; Karaksheva, T. A.; Sahu, V.; Martin, C.; Nakagawa, H.; Gabre, J.
10.1101/2024.10.08.617209 — developmental biology — Posted on 2024-10-10
4047 TOMM40-APOE chimera linking Alzheimer's highest risk genes: a new pathway for mitochondria regulation and APOE4 pathogenesis
Xu, J.; Duan, J.; Cai, Z.; Arai, C.; Di, C.; Venters, C. C.; Xu, J.; Jones, M.; So, B.-R.; Dreyfuss, G.
10.1101/2024.10.09.617477 — cell biology — Posted on 2024-10-10
4048 TRIM37 employs peptide motif recognition and substrate-dependent oligomerization to prevent ectopic spindle pole assembly
Bellaart, A.; Brambila, A.; Xu, J.; Diaz, F. M.; Deep, A.; Anzola, J.; Meitinger, F.; Ohta, M.; Corbett, K. D.; Desai, A.; Oegema, K.
10.1101/2024.10.09.617493 — cell biology — Posted on 2024-10-10
4051 Cultured Bacteria Isolated from Primary Sclerosing Cholangitis Patient Bile Induce Inflammation and Cell Death
Powell, C. E.; McCurry, M. D.; Quevedo, S. F.; Ventura, L.; Krishnan, K.; Dave, M.; Mahmood, S. D.; Specht, K.; Bordia, R.; Pratt, D. S.; Korzenik, J. R.; Devlin, A. S.
10.1101/2024.10.08.617321 — microbiology — Posted on 2024-10-09
4052 IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY REVEALED BY BRAIN-METASTATIC MELANOMA MODELS.
Daugherty-Lopes, A.; Perez-Guijarro, E.; Gopalan, V.; Rappaport, J.; Chen, Q.; Huang, A.; Lam, K. C.; Chin, S.; Ebersole, J.; Wu, E.; Needle, G. A.; Church, I.; Kyriakopoulos, G.; Xie, S.; Zaho, Y.; Gruen, C.; Sassano, A.; Araya, R. E.; Thorkelsson, A.; Smith, C.; Lee, M. P.; Hannenhalli, S.; Day, C.-P.; Merlino, G.; Goldszmid, R. S.
10.1101/2024.08.26.609785 — immunology — Posted on 2024-10-09
4053 Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice
Hale, M.; Takehara, K. K.; Thouvenel, C. D.; Moustafa, D. A.; Repele, A.; Fontana, M. F.; Netland, J.; McNamara, S.; Gibson, R. L.; Goldberg, J. B.; Rawlings, D. J.; Pepper, M.
10.1101/2024.04.08.588618 — immunology — Posted on 2024-10-09
4054 Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers
Krasik, S. V.; Bryushkova, E. A.; Sharonov, G. V.; Myalik, D. S.; Shurganova, E. V.; Komarov, D. V.; Shagina, I. A.; Shpudeiko, P. S.; Turchaninova, M. A.; Vakhitova, M. T.; Samoylenko, I. V.; Marinov, D. T.; Demidov, L. V.; Zagainov, V. E.; Chudakov, D. M.; Serebrovskaya, E. O.
10.1101/2023.04.16.537028 — immunology — Posted on 2024-10-09
4060 Amylin receptor subunit interactions are modulated by agonists and determine signaling
Gostynska, S. E.; Karim, J. A.; Ford, B. E.; Gordon, P. H.; Babin, K. M.; Inoue, A.; Lambert, N. A.; Pioszak, A. A.
10.1101/2024.10.09.617487 — biochemistry — Posted on 2024-10-09
4061 Focal persistence and phylodynamics of Heartland virus in Georgia
Bellman, S.; Shariatzadeh, N.; Ferrell, T.; Long, A.; Aeschleman, L.; Fausett, E.; Walsh, T.; Cleary, S.; Roeske, I.; Ojeda, E.; Schwab, M.; Dakanay, H.; Telford, S. R.; Goethert, H. K.; Vazquez-Prokopec, G.; Piantadosi, A.
10.1101/2024.10.07.616953 — genomics — Posted on 2024-10-09
4065 Convergent effects of different anesthetics on changes in phase alignment of cortical oscillations
Bardon, A. G.; Ballesteros, J. J.; Brincat, S. L.; Roy, J. E.; Mahnke, M. K.; Ishizawa, Y.; Brown, E. N.; Miller, E. K.
10.1101/2024.03.20.585943 — neuroscience — Posted on 2024-10-09
4066 Template-Independent Enzymatic RNA Synthesis
Karalkar, N. B.; Benner, S. A.; Kent, T.; Tredinnick, T.; Pomerantz, R.; betancurt-Anzola, l.; Delarue, M.
10.1101/2024.10.09.617423 — synthetic biology — Posted on 2024-10-09
4068 Tunable, self-contained gene dosage control via proteolytic cleavage of CRISPR-Cas systems
Katz, N.; An, C.; Lee, Y.-J.; Tycko, J.; Zhang, M.; Kang, J.; Bintu, L.; Bassik, M. C.; Huang, W.-H.; Gao, X. J.
10.1101/2024.10.09.617463 — synthetic biology — Posted on 2024-10-09
4070 MAGIC matrices: freeform bioprinting materials to support complex and reproducible organoid morphogenesis
Graham, A. J.; Khoo, M. W. L.; Srivastava, V.; Viragova, S.; Kim, H.; Parekh, K.; Hennick, K. M.; Bird, M.; Goldhammer, N.; Yu, J. Z.; Morley, C. D.; Lebel, P.; Kumar, S.; Rosenbluth, J. M.; Nowakowski, T. J.; Klein, O. D.; Gomez-Sjoberg, R.; Gartner, Z. J.
10.1101/2024.02.01.578324 — bioengineering — Posted on 2024-10-09
4071 Structural basis of TMPRSS11D specificity and autocleavage activation
Fraser, B. J.; Wilson, R. P.; Ilyassov, O.; Lac, J.; Dong, A.; Li, Y.-Y.; Seitova, A.; Li, Y.; Hejazi, Z.; Kenney, T. M. G.; Penn, L. Z.; Edwards, A.; Morin, G. B.; Benard, F.; Arrowsmith, C. H.
10.1101/2024.10.09.617371 — biochemistry — Posted on 2024-10-09
4072 Cryo-EM of native membranes reveals an intimate connection between the Krebs cycle and respiration in mycobacteria
Di Trani, J. M.; Yu, J.; Courbon, G. M.; Rodriguez, A. P. L.; Cheung, C.-Y.; Liang, Y.; Coupland, C. E.; Bueler, S. A.; Cook, G. M.; Brzezinski, P.; Rubinstein, J. L.
10.1101/2024.10.09.617439 — biochemistry — Posted on 2024-10-09
4073 Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition
Petzold, G.; Gainza, P.; Annunziato, S.; Lamberto, I.; Trenh, P.; McAllister, L. A.; DeMarco, B.; Schwander, L.; Bunker, R. D.; Zlotosch, M.; SriRamaratnam, R.; Gilberto, S.; Langousis, G.; Donckele, E. J.; Quan, C.; Strande, V.; De Donatis, G. M.; Alabi, S. B.; Alers, J.; Matysik, M.; Staehly, C.; Dubois, A.; Osmont, A.; Garskovas, M.; Lyon, D.; Wiedmer, L.; Oleinikovas, V.; Lieberherr, R.; Rubin, N. T.; Lam, D. T.; Widlund, N. I.; Ritzen, A.; Caceres, R. M.; Vigil, D.; Tsai, J.; Wallace, O.; Peluso, M.; Sadok, A.; Paterson, A.; Zarayskiy, V.; Fasching, B.; Bonenfant, D.; Warmuth, M.; Castle,
10.1101/2024.10.07.616933 — biochemistry — Posted on 2024-10-09
4074 Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM
Wu, C.; Meuser, M. E.; Rey, J. S.; Meshkin, H.; Yang, R.; Devarkar, S. C.; Freniere, C.; Shi, J.; Aiken, C.; Perilla, J. R.; Xiong, Y.
10.1101/2024.10.09.617473 — biochemistry — Posted on 2024-10-09
4077 Multicomponent Thiolactone-Based Ionizable Lipid Screening Platform for an Efficient and Tunable mRNA Delivery to the Lungs
Pena, A.; Heredero, J.; Blandin, B.; Mata, E.; De Miguel, D.; Toro, A.; Alejo, T.; Casabona, D.; Lopez, A.; Gallego-Lleyda, A.; Perez-Herran, E.; Martinez-Olivan, J.; Gimenez-Warren, J.
10.1101/2024.10.09.617396 — biochemistry — Posted on 2024-10-09
4082 The biological consequences of knockout of genes involved in the synthesis and metabolism of H2S in Drosophila melanogaster
Zatsepina, O. G.; Chilova, V. Y.; Chuvakova, L. N.; Garbuz, D. G.; Rezvykh, A. P.; Funilov, S. Y.; Davletshin, A. I.; Sorokina, S. Y.; Nikitina, E. A.; Gorenskaya, O. V.; Evgen'ev, M. B.
10.1101/2024.10.09.617392 — molecular biology — Posted on 2024-10-09
4083 An ancient competition for the conserved branchpoint sequence influences physiological and evolutionary outcomes in splicing
Pereira de Castro, K. L.; Abril, J. m.; Liao, K.-C.; Hao, H.; Donohue, J. P.; Russell, W. K.; Fagg, W. S.
10.1101/2024.10.09.617384 — molecular biology — Posted on 2024-10-09
4085 Identification of miR136, miR155, and miR183 in vascular calcification in human peripheral arteries
Le Corvec, T.; Burgaud, M.; Steenman, M.; Tesfaye, R. A.; Goueffic, Y.; Maurel-Desanlis, B.; Quillard, T.
10.1101/2024.10.09.616039 — molecular biology — Posted on 2024-10-09
4087 Sm-site containing mRNAs can accept Sm-rings and are downregulated in Spinal Muscular Atrophy
Blatnik, A. J.; Sanjeev, M.; Slivka, J. A.; Pastore, B.; Embree, C. M.; Tang, W.; Singh, G.; Burghes, A. H. M.
10.1101/2024.10.09.617433 — molecular biology — Posted on 2024-10-09
4088 The mechanism of bacterial defense system DdmDE from Lactobacillus casei
Pingping, H.; Purui, Y.; Lijie, G.; Wenying, F.; Zhaoxing, L.; Jingxian, L.; Jianping, K.; Yue, Y.; Meiling, L.; Yibei, X.; Meirong, C.
10.1101/2024.10.09.617351 — molecular biology — Posted on 2024-10-09
4090 Gut Bacteria Metabolize Natural and Synthetic Steroid Hormones via the Reductive OsrABC Pathway
Jacoby, C.; Scorza, K.; Ecker, L.; McMillin, M.; Ramaswamy, R.; Sundararajan, A.; Sidebottom, A. M.; Lin, H.; Dufault-Thompson, K.; Hall, B.; Jiang, X.; Light, S. H.
10.1101/2024.10.08.617280 — microbiology — Posted on 2024-10-09
4091 Novel amylase genes enable utilisation of resistant starch by bifidobacteria relevant to early-life microbiome development
Millar, M. E.; Abele, M.; Harris, H. C.; Koev, T. T.; Telatin, A.; Kiu, R.; Van Sinderen, D.; Khimyak, Y. Z.; Ludwig, C.; Hall, L. J.; Warren, F. J.
10.1101/2024.10.09.617373 — microbiology — Posted on 2024-10-09
4094 Unveiling Crocosphaera responses to phosphorus depletion: insights from genome analysis and functional characterization
Caille, C.; Rabouille, S.; Ortega-retuerta, E.; Denis, Y.; Crispi, O.; Marie, B.; Pujo-pay, M.; Daric, V.; TALLA, E.; LATIFI, A.
10.1101/2024.10.09.617355 — microbiology — Posted on 2024-10-09
4095 Bio-engineering a common probiotic to exploit colonic inflammation promotes reliable efficacy in translational models of colitis
Verdugo Meza, A.; Gill, S. K.; Godovannyi, A.; Adur, M. K.; Barnett, J. A.; Estaki, M.; Ye, J.; Haskey, N.; Mehain, H.; Josephson, J. K.; Ishida, R.; Ghesquiere, C.; Sly, L. M.; Gibson, D. L.
10.1101/2024.10.08.617317 — microbiology — Posted on 2024-10-09
4097 A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Completely Protective Multivalent Mucosal Dual Vaccine Against COVID-19 and Flu
Zhu, J.; Sha, J.; Batra, H.; Jain, S.; Wu, X.; Hendrix, E.; Kilgore, P. B.; Sun, K.; Plante, K. S.; Plante, J. A.; Walker, J.; Tao, P.; Chopra, A. K.; Rao, V. B.
10.1101/2024.10.09.617418 — microbiology — Posted on 2024-10-09
4100 Making Moral Decisions With Artificial Agents As Advisors. An fNIRS Study
Fabre, E. F.; Mouratille, D.; Bonnemain, V.; Palmiotti, G.-P.; Causse, M.
10.1101/2024.03.05.583335 — neuroscience — Posted on 2024-10-09
4101 Multi-echo Acquisition and Thermal Denoising Advances Precision Functional Imaging
Moser, J.; Nelson, S. M.; Koirala, S.; Madison, T.; Labonte, A. K.; Morales Carrasco, C.; Feczko, E.; Moore, L. A.; Lundquist, J. T.; Weldon, K. B.; Grimsrud, G.; Hufnagle, K.; Ahmed, W.; Myers, M. J.; Adeyemo, B.; Snyder, A. Z.; Gordon, E. M.; Dosenbach, N. U. F.; Trevo-Clemmens, B.; Larsen, B.; Moeller, S.; Yacoub, E.; Vizioli, L.; Ugurbil, K.; Laumann, T. O.; Sylvester, C. M.; Fair, D. A.
10.1101/2023.10.27.564416 — neuroscience — Posted on 2024-10-09
4102 Probing the role of synaptic adhesion molecule RTN4RL2 in setting up cochlear connectivity
Karagulyan, N.; Überegger, M.; Qi, Y.; Babai, N.; Hofer, F.; Johnson Chacko, L.; Wang, F.; Luque, M.; Glueckert, R.; Schrott-Fischer, A.; Hua, Y.; Moser, T.; Bandtlow, C.
10.1101/2024.09.16.613011 — neuroscience — Posted on 2024-10-09
4103 An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration
Leventhal, M. J.; Zanella, C. A.; Kang, B.; Peng, J.; Gritsch, D.; Liao, Z.; Bukhari, H.; Wang, T.; Pao, P.-C.; Danquah, S.; Benetatos, J.; Nehme, R.; Farhi, S.; Tsai, L.-H.; Dong, X.; Scherzer, C.; Feany, M. B.; Fraenkel, E.
10.1101/2024.03.17.585262 — systems biology — Posted on 2024-10-09
4105 Physical confinement selectively favours bacterial growth based on cell shape
Sreepadmanabh, M.; Ganesh, M.; Sanjenbam, P.; Kurzthaler, C.; Agashe, D.; Bhattacharjee, T.
10.1101/2024.05.06.592621 — biophysics — Posted on 2024-10-09
4110 Two distinct modes of hemodynamic responses across the human cortex
Epp, S. M.; Castrillon, G.; Yuan, B.; Andrews-Hanna, J.; Preibisch, C.; Riedl, V.
10.1101/2023.12.08.570806 — neuroscience — Posted on 2024-10-09
4115 Motifs of human hippocampal and cortical high frequency oscillations structure processing and memory of naturalistic stimuli
Mishra, A.; Tostaeva, G.; Nentwich, M.; Espinal, E.; Markowitz, N.; Winfield, J.; Freund, E.; Gherman, S.; Mehta, A. D.; Bickel, S.
10.1101/2024.10.08.617305 — neuroscience — Posted on 2024-10-09
4117 LeDNA: a cut-and-build toolkit to democratize education on CRISPR gene editing technology
Kundlatsch, G. E.; Rodrigues, A. d. S. L.; Zocca, V. F. B.; Amorim, L. A. d. S.; de Paiva, G. B.; Neto, A. P. d. S.; Campos, J. A. D. B.; Pedrolli, D. B.
10.1101/2024.10.09.617025 — scientific communication and education — Posted on 2024-10-09
4118 Cell-free immuno-profiling on a genetically programmed biochip
Dupin, A.; Vonshak, O.; Arad, V.; Levanon, M.; Avidan, N.; Divon, Y.; Peleg, S.; Thompson, S.; Noireaux, V.; Daube, S. S.; Bar-Ziv, R. H.
10.1101/2024.10.09.617356 — bioengineering — Posted on 2024-10-09
4119 Independent effects of testosterone, estradiol, and sex chromosomes on gene expression in immune cells of trans- and cisgender individuals
Harris, R. M.; Whitfield, T.; Blanton, L. V.; Skaletsky, H.; Blumen, K.; Hyland, P.; McDermott, E.; Summers, K.; Hughes, J. F.; Jackson, E.; Teglas, P.; Liu, B.; Chan, Y.-M.; Page, D. C.
10.1101/2024.10.08.617275 — genomics — Posted on 2024-10-09
4120 WITHDRAWN: DiDBiT-TMT: A novel method to quantify changes in the proteomic landscape induced by neural plasticity
Gamaleldin, M.; Yu, N.-K.; Diedrich, J.; Ma, Y.; Wienand, A.; McClatchy, D.; Nykjaer, A.; Nabavi, S.; Yates, J. R.
10.1101/2024.03.07.583889 — neuroscience — Posted on 2024-10-09
4121 Cryo-EM structures of the E. coli Ton and Tol motor complexes
Celia, H.; Botos, I.; Beach, B. M.; Ghirlando, R.; Lloubes, R.; Buchanan, S. K.
10.1101/2024.10.08.617233 — molecular biology — Posted on 2024-10-09
4122 Circadian clock features define novel breast cancer subtypes and shape drug sensitivity
Ector, C.; Didier, J.; De Landtsheer, S.; Nordentoft, M. S.; Schmal, C.; Keilholz, U.; Herzel, H.; Kramer, A.; Sauter, T.; Granada, A. E.
10.1101/2024.10.07.617001 — cancer biology — Posted on 2024-10-09
4123 Structure of the F-tractin-F-actin complex
Shatskiy, D.; Sivan, A. M.; Wedlich-Soldner, R.; Belyy, A.
10.1101/2024.10.07.616643 — biochemistry — Posted on 2024-10-09
4125 The genetic interaction map of the human solute carrier superfamily
Wolf, G.; Leippe, P.; Onstein, S.; Goldmann, U.; Frommelt, F.; Teoh, S. T.; Girardi, E.; Wiedmer, T.; Superti-Furga, G.
10.1101/2024.10.07.616442 — systems biology — Posted on 2024-10-09
4127 Tokenizing Foldable Protein Structures with Machine-Learned Artificial Amino-Acid Vocabulary
Lin, X.; Chen, Z.; Li, Y.; Ma, Z.; Fan, C.; Cao, Z.; Feng, S.; Gao, Y. Q.; Zhang, J.
10.1101/2023.11.27.568722 — bioinformatics — Posted on 2024-10-09
4128 Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling
Mcleod, J. C.; Lim, C.; Stokes, T.; Sharif, J.-A.; Zeynalli, V.; Wiens, L.; D'Souza, A. C.; Colenso-Semple, L.; McKendry, J.; Morton, R. W.; Mitchell, C. J.; Oikawa, S. Y.; Wahlestedt, C.; Chapple, P.; McGlory, C.; Timmons, J. A.; Phillips, S. M.
10.1101/2024.08.11.606848 — bioinformatics — Posted on 2024-10-09
4132 Within-ejaculate haploid selection reduces disease biomarkers in human sperm
Marcu, D.; Cohen-Krais, J.; Godden, A.; Alavioon, G.; Martins, C.; Almstrup, K.; Saalbach, G.; Immler, S.
10.1101/2024.10.08.617222 — molecular biology — Posted on 2024-10-09
4133 Proteomic And Transcriptomic Host Biomarkers For Detection Of Pleural Tuberculosis
Almeida, M. R.; van Hooij, A.; Musch, N.; Verhard, E.; van Veen, S.; Pierneef, L.; de Jong, D.; Correa, R. d. S.; Mafort, T. T.; Rufino, R.; de Macedo, C. S.; M. Kielbasa, S.; Corstjens, P. L. A. M.; Rodrigues, L. S.; Geluk, A.
10.1101/2024.10.08.617199 — microbiology — Posted on 2024-10-09
4135 Focal persistence and phylodynamics of Heartland virus in Georgia
Bellman, S.; Shariatzadeh, N.; Ferrell, T.; Long, A.; Aeschleman, L.; Fausett, E.; Walsh, T.; Cleary, S.; Roeske, I.; Ojeda, E.; Schwab, M.; Dakanay, H.; Telford, S. R.; Goethert, H. K.; Vazquez-Prokopec, G.; Piantadosi, A.
10.1101/2024.10.07.616953 — genomics — Posted on 2024-10-09
4137 Aberrant expression prediction across human tissues
Hölzlwimmer, F. R.; Lindner, J.; Tsitsiridis, G.; Wagner, N.; Yepez, V. A.; Casale, F. P.; Gagneur, J.
10.1101/2023.12.04.569414 — genetics — Posted on 2024-10-09
4139 Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle
Tomasini, C.; Cuche, C.; Ay, S.; Collard, M.; Cui, B.; Rashid, M.; Bhattacharjee, S.; Buchrieser, J.; Luchsinger, C.; Bertelli, C.; Uversky, V.; Diaz-Griffero, F.; Di Nunzio, F.
10.1101/2024.10.06.616889 — microbiology — Posted on 2024-10-09
4141 Sub-3 A resolution protein structure determination by single-particle cryo-EM at 100 keV
Karia, D.; Koh, A. F.; Yang, W.; Cushing, V. I.; Basanta, B.; Mihaylov, D. B.; Khavnekar, S.; Vyroubal, O.; Malinsky, M.; Shanel, O.; Dolezal, V.; Plitzko, J. M.; Yu, L.; Lander, G. C.; Aricescu, A. R. C.; Greber, B. J.; Kotecha, A.
10.1101/2024.09.05.611417 — biophysics — Posted on 2024-10-09
4142 A Wearable Mindfulness Brain-Computer Interface for Alleviating Car Sickness
Zhu, J.; Bao, X.; Huang, Q.; Wang, T.; Huang, L.; Han, Y.; Huang, H.; Zhu, J.; Qu, J.; Li, K.; Chen, D.; Jiang, Y.; Xu, K.; Wang, Z.; Wu, W.; Li, Y.
10.1101/2024.09.25.614936 — bioengineering — Posted on 2024-10-09
4145 The molecular chronology of mammary epithelial cell fate switching
Vallmajo-Martin, Q.; Ma, Z.; Srinivasan, S.; Murali, D.; Dravis, C.; Mukund, K.; Subramaniam, S.; Wahl, G. M.; Lytle, N. K.
10.1101/2024.10.08.617155 — cell biology — Posted on 2024-10-09
4146 25-hydroxycholesterol promotes brain endothelial dysfunction by remodelling cholesterol metabolism
Tapia, V. S.; Withers, S. E.; Zhou, R.; Bennington, A.; Hedley, F.; El Khouja, A.; Luka, N.; Massimo, M.; Crilly, S.; Long, K. R.; Lawrence, C. B.; Kasher, P. R.
10.1101/2024.05.10.590792 — neuroscience — Posted on 2024-10-09
4147 The influence of the head model on magnetoencephalography-derived functional connectivity fingerprinting
Schelfhout, M.; Hinault, T. T.; Lago, S.; Arcara, G.; Amico, E.; Fraschini, M.; Marinazzo, D.
10.1101/2024.08.05.606621 — neuroscience — Posted on 2024-10-09
4148 Reevaluating the Neural Noise Hypothesis in Dyslexia: Insights from EEG and 7T MRS Biomarkers
Glica, A.; Wasilewska, K.; Jurkowska, J.; Zygierewicz, J.; Kossowski, B.; Jednorog, K.
10.1101/2024.06.11.598476 — neuroscience — Posted on 2024-10-09
4152 Annulate Lamellae biogenesis is essential for nuclear pore function
Lin, J.; Agote-Aran, A.; Liao, Y.; Schoch, R.; Ronchi, P.; Cochard, V.; Zhu, R.; Kleiss, C.; Ruff, M.; Chevreux, G.; Schwab, Y.; Klaholz, B.; Sumara, I.
10.1101/2024.10.08.617205 — cell biology — Posted on 2024-10-09
4153 Polybacterial Intracellular Macromolecules Shape Single-Cell Epikine Profiles in Upper Airway Mucosa
Easter, Q. T.; Alvarado-Martinez, Z.; Kunz, M.; Matuck, B.; Rupp, B.; Weaver, T.; Ren, Z.; Tata, A. T.; Caballero-Perez, J.; Oscarson, N.; Hasuike, A.; Ghodke, A.; Kimple, A.; Tata, P. R.; Randell, S. H.; Koo, H.; Ko, K. I.; Byrd, K. M.
10.1101/2024.10.08.617279 — cell biology — Posted on 2024-10-09
4154 Molecular model of a bacterial flagellar motor in situ reveals a "parts-list" of protein adaptations to increase torque
Drobnic, T.; Cohen, E. J.; Calcraft, T.; Alzheimer, M.; Froschauer, K.; Svensson, S.; Hoffmann, W. H.; Singh, N.; Garg, S. G.; Henderson, L.; Umrekar, T.; Nans, A.; Ribardo, D.; Pedaci, F.; Nord, A. L.; Hochberg, G.; Hendrixson, D. R.; Sharma, C. M.; Rosenthal, P.; Beeby, M.
10.1101/2023.09.08.556779 — molecular biology — Posted on 2024-10-09
4155 Resting-state hyper- and hypo-connectivity in early schizophrenia: which tip of the iceberg should we focus on?
Tomecek, D.; Kolenic, M.; Rehak Buckova, B.; Tintera, J.; Spaniel, F.; Horacek, J.; Hlinka, J.
10.1101/2024.09.20.613853 — neuroscience — Posted on 2024-10-09
4159 Tissue stiffness mapping by light sheet elastography
Zhu, M.; Zhang, K.; Thomas, E. C.; Xu, R.; Ciruna, B.; Hopyan, S.; Sun, Y.
10.1101/2023.12.09.570896 — bioengineering — Posted on 2024-10-09
4161 Loss of Flower/FLWR-1 induces an increase in neuronal excitability and causes defective recycling of synaptic vesicles
Seidenthal, M.; Redzovic, J.; Liewald, J. F.; Rentsch, D.; Shapiguzov, S.; Schuh, N.; Eimer, S.; Gottschalk, A.
10.1101/2024.10.07.617020 — neuroscience — Posted on 2024-10-09
4162 Perinatal Reduction of Genetically Aberrant Neurons from Human Cerebral Cortex
Shao, D. D.; Zhao, Y.; Ghosh, U.; Brew, J.; Zhao, S.; Qian, X.; Tran, J.; Taketomi, T.; Tsuruta, F.; Park, P. J.; Walsh, C. A.
10.1101/2024.10.08.617159 — neuroscience — Posted on 2024-10-09
4164 Spatial mutual nearest neighbors for spatial transcriptomics data
Zhou, H.; Panwar, P.; Guo, B.; Hallinan, C.; Ghazanfar, S.; Hicks, S. C.
10.1101/2024.10.08.615307 — bioinformatics — Posted on 2024-10-09
4165 Spatial Single-Cell Mapping of Transcriptional Differences Across Genetic Backgrounds in Mouse Brains
Hemminger, Z.; Sanchez-Tam, G.; De Ocampo, H.; Wang, A.; Underwood, T.; Xie, F.; Zhao, Q.; Song, D.; Li, J. J.; Dong, H.; Wollman, R.
10.1101/2024.10.08.617260 — genomics — Posted on 2024-10-09
4166 Computational neurodevelopment: infant decision-making in changing environments
Adams, R. A.; Billing, A.; Baljer, L.; Smith, E. S.; Cooper, R. J.; Lawson, R. P.
10.1101/2024.10.08.617314 — neuroscience — Posted on 2024-10-09
4167 Scalable Extraction of Airway Mucins from Porcine Trachea
Yang, S.; Engle, E. M.; Boboltz, A.; Kumar, S.; Stern, A.; Duncan, G.
10.1101/2024.10.08.617223 — biochemistry — Posted on 2024-10-08
4170 Vault RNAs aid viral infection by facilitating nuclear export of hnRNP C and ELAVL1
Stok, J. E.; van der Kooij, S. B.; Gravekamp, D.; ter Haar, L. R.; de Wolf, J. W.; Salgado-Benvindo, C.; Nelemans, T.; Grijmans, B. J. M.; Tjokrodirijo, R. T. N.; de Ru, A. H.; van Veelen, P. A.; van Hemert, M. J.; Kikkert, M.; van der Veen, A. G.
10.1101/2024.10.07.616963 — molecular biology — Posted on 2024-10-08
4173 The Escherichia coli replication initiator DnaA is titrated on the chromosome
Olivi, L.; Köstlbacher, S.; Langendoen, M.; Claassens, N. J.; Ettema, T. J. G.; van der Oost, J.; ten Wolde, P. R.; Hohlbein, J.; Staals, R. H. J.
10.1101/2024.10.07.617004 — molecular biology — Posted on 2024-10-08
4174 Pseudohypoxia-stabilized HIF2α transcriptionally inhibits MNRR1, a druggable target in MELAS
Purandare, N.; Pasupathi, V.; Xi, Y.; Rajan, V.; Vegh, C.; Firestine, S.; Kozicz, T.; Fribley, A. M.; Grossman, L. I.; Aras, S.
10.1101/2024.10.07.617011 — molecular biology — Posted on 2024-10-08
4176 Thiol Stress Fuels Pyrazinamide Action Against Mycobacterium tuberculosis
Ostrer, L.; Crooks, T. A.; Howe, M. D.; Vo, S.; Jia, Z.; Hegde, P.; Aldrich, C. C.; Baughn, A. D.
10.1101/2024.10.08.617272 — microbiology — Posted on 2024-10-08
4178 Environment and diet shape the geography-specific Drosophila melanogaster microbiota composition
Gale, J. T.; Kreutz, R.; Gottfredson Morgan, S. J.; Davis, E. K.; Hough, C.; Cisneros Cancino, W. A.; Burnside, B.; Barney, R.; Hunsaker, R.; Tanner Hoyt, A.; Cluff, A.; Nosker, M.; Sefcik, C.; Beales, E.; Beltz, J.; Frandsen, P. B.; Schmidt, P.; Chaston, J. M.
10.1101/2024.10.07.617096 — microbiology — Posted on 2024-10-08
4179 Deciphering the chemical landscape and potential ecological function of RiPPs from the untapped Archaea domain
Zhiman, S.; Cunlei, C.; Ying, G.; Xiaoqian, L.; Gengfan, W.; Haoyu, L.; Qianlin, Z.; Peiyan, C.; Junliang, Z.; Wenhua, L.; Yong-xin, L.
10.1101/2024.10.07.616454 — microbiology — Posted on 2024-10-08
4181 MreC-MreD structure reveals a multifaceted interface that controls MreC conformation
Gilman, M. S. A.; Shlosman, I.; Guerra, D. D. S.; Domecillo, M.; Fivenson, E. M.; Bourett, C.; Bernhardt, T. G.; Polizzi, N. F.; Loparo, J. J.; Kruse, A. C.
10.1101/2024.10.08.617240 — microbiology — Posted on 2024-10-08
4183 Two temperature-responsive RNAs act in concert: The small RNA CyaR and the mRNA ompX
Guanzon, D. A.; Pienkoss, S.; Brandenburg, V. B.; Roeder, J.; Dietze, A.; Wimbert, A.; Twittenhoff, C.; Narberhaus, F.
10.1101/2024.10.08.617194 — microbiology — Posted on 2024-10-08
4185 An Autonomous Microbial Sensor Enables Long-term Detection of TNT Explosive in Natural Soil
Essington, E. A.; Vezeau, G. E.; Cetnar, D. P.; Grandinette, E.; Bell, T. H.; Salis, H. M.
10.1101/2024.10.08.617249 — synthetic biology — Posted on 2024-10-08
4186 Validation of DoriVac (DNA origami vaccine) efficacy in a metastatic melanoma model
Rajwar, A.; Dembele, H.; Graveline, A.; Vernet, A.; Sanchez, M.; Bardales, S.; Kwon, I. C.; Ryu, J. H.; Shih, W. M.; Zeng, Y. C.
10.1101/2024.10.08.617273 — synthetic biology — Posted on 2024-10-08
4187 Enhancement of Enzymatic Activity by Biomolecular Condensates through pH Buffering
Stoffel, F.; Papp, M.; Küffner, A. M.; Benitez-Mateos, A.; Jacquat, R. P. B.; Gil-Garcia, M.; Galvanetto, N.; Faltova, L.; Arosio, P.
10.1101/2024.10.08.617196 — biochemistry — Posted on 2024-10-08
4191 Integrating N-glycan and CODEX imaging reveal cell-specific protein glycosylation in healthy human lung
Velickovic, D.; Purkerson, J.; Bhotika, H.; Huyck, H.; Clair, G. C.; Pryhuber, G.; Anderton, C. R.
10.1101/2024.10.08.617274 — biochemistry — Posted on 2024-10-08
4192 Direct mitochondrial import of lactate supports resilient carbohydrate oxidation
Cluntun, A. A.; Visker, J. R.; Velasco-Silva, J. N.; Lang, M. J.; Cedeno-Rosario, L.; Shankar, T. S.; Hamouche, R.; Ling, J.; Kim, J. E.; Toshniwal, A. G.; Low, H.; Cunningham, C. N.; Carrington, J.; Catrow, J. L.; Pearce, Q.; Wells, C. E.; Jeong, M.-Y.; Bott, A. J.; Narbona-Perez, A. J.; Stanley, C.; Li, Q.; Morgan, J. T.; Yadav, T.; Swiatek, W. I.; Ramadurai, D. K. A.; Eberhardt, D. R.; Chaudhuri, D.; Rothstein, J. D.; Muoio, D. M.; Paulo, J. A.; Gygi, S. P.; Cox, J. E.; Funai, K.; Navankasattusas, S.; Baker, S. A.; Drakos, S. G.; Rutter, J.; Ducker, G. S.
10.1101/2024.10.07.617073 — biochemistry — Posted on 2024-10-08
4194 Regulating IL-2 immune signaling function via a core allosteric structural network
Woodward, C. H.; Solieva, S. O.; Hwang, D.; De Paula, V. S.; Fabilane, C. S.; Young, M. C.; Trent, T.; Teeley, E. C.; Majumdar, A.; Spangler, J. B.; Bowman, G. R.; Sgourakis, N. G.
10.1101/2024.10.07.617024 — biochemistry — Posted on 2024-10-08
4195 Unconventional binding of Calmodulin to CHK2 kinase inhibits catalytic activity
Horne, C. R.; Wang, T.; Young, S. N.; Dite, T. A.; Nyvall, H. G.; Suresh, S.; Davies, K. A.; Mather, L. J.; Dagley, L. F.; Manning, G.; Means, A. R.; Burke, J. E.; Petersen, J.; Scott, J. W.; Murphy, J. M.
10.1101/2024.10.08.617309 — biochemistry — Posted on 2024-10-08
4196 A filamentous scaffold for gene regulation
Rasmussen, T.; Kuspert, J.; Schonemann, L.; Geiger, D.; Bottcher, B.
10.1101/2024.10.07.617013 — biochemistry — Posted on 2024-10-08
4200 Interpretable and predictive models based on high-dimensional data in ecology and evolution
Jahner, J. P.; Buerkle, C. A.; Gannon, D. G.; Grames, E. M.; McFarlane, S. E.; Siefert, A.; Bell, K. L.; DeLeo, V. L.; Forister, M. L.; Harrison, J. G.; Laughlin, D. C.; Patterson, A. C.; Powers, B. F.; Werner, C. M.; Oleksy, I. A.
10.1101/2024.03.15.585297 — genomics — Posted on 2024-10-08
4201 Giant transposons promote strain heterogeneity in a major fungal pathogen
Gluck-Thaler, E.; Forsythe, A.; Puerner, C.; Stajich, J. E.; Croll, D.; Cramer, R. A.; Vogan, A. A.
10.1101/2024.06.28.601215 — microbiology — Posted on 2024-10-08
4202 Lower Aperiodic Activity is Associated with Reduced Verbal Fluency Performance Across Adulthood
McKeown, D. J.; Roberts, E.; Finley, A. J.; Kelley, N. J.; Keage, H. A. D.; Schinazi, V. R.; Baumann, O.; Moustafa, A. A.; Angus, D. J.
10.1101/2024.08.13.607827 — neuroscience — Posted on 2024-10-08
4204 Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice
Ishchenko, Y.; Jeng, A. T.; Feng, S.; Nottoli, T.; Manriquez-Rodriguez, C.; Nguyen, K.; Carrizales, M. G.; Vitarelli, M. J.; Corcoran, E. E.; Greer, C. A.; Myers, S. A.; Koleske, A. J.
10.1101/2024.01.05.574442 — neuroscience — Posted on 2024-10-08
4205 Concerted modulation of spontaneous behavior and time-integrated whole-brain neuronal activity by serotonin receptors
Friedmann, D.; Gonzalez, X.; Moses, A.; Watts, T.; Degleris, A.; Ticea, N.; Song, J. H.; Datta, S. R.; Linderman, S. W.; Luo, L.
10.1101/2024.08.02.606282 — neuroscience — Posted on 2024-10-08
4206 Chemical inhibition of stomatal differentiation by perturbation of the master-regulatory bHLH heterodimer via an ACT-Like domain
Nakagawa, A.; Sepuru, K. M.; Yip, S. J. A.; Seo, H.; Coffin, C. M.; Hashimoto, K.; Li, Z.; Segawa, Y.; Iwasaki, R.; Kato, H.; Kurihara, D.; Kim, S.; Aihara, Y.; Kinoshita, T.; Itami, K.; Han, S.-K.; Murakami, K.; Torii, K. U.
10.1101/2023.11.02.565226 — plant biology — Posted on 2024-10-08
4208 Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
Abramsson, M. L.; Corey, R. A.; Skerle, J. L.; Persson, L. J.; Anden, O.; Oluwole, A. O.; Howard, R. J.; Lindahl, E.; Robinson, C. V.; Strisovsky, K.; Marklund, E. G.; Drew, D.; Stansfeld, P. J.; Landreh, M.
10.1101/2024.05.27.592301 — biochemistry — Posted on 2024-10-08
4210 Computational design of a thermostable de novo biocatalyst for whole cell biotransformations
Elaily, W.; Stoll, D.; Chakatok, M.; Aleotti, M.; Grill, B.; Lechner, H.; Hall, M.; Oberdorfer, G.
10.1101/2024.10.07.617055 — biochemistry — Posted on 2024-10-08
4212 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Patel, S. P.; Munugala, C.; Bloom, J. S.; Kruglyak, L.
10.1101/2023.12.07.570640 — genetics — Posted on 2024-10-08
4216 Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics
Peshkin, L.; Daldello, E. M.; Van Itallie, E. S.; Sonnett, M.; Kreuzer, J.; Haas, W.; Kirschner, M. W.; Jessus, C.
10.1101/2024.07.26.605364 — developmental biology — Posted on 2024-10-08
4220 Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2
Ehlers, L.; Hombrouck, A.; Wouters, M.; Pillay, B.; Delafontaine, S.; Bucciol, G.; Baggio, M.; Dzhus, M.; Ebstein, F.; Jacquemyn, M.; De Somer, L.; Schrijvers, R.; Vanderschueren, S.; Cassiman, D.; Kirchner, M.; Mertins, P.; Mashreghi, M.-F.; Kallinich, T.; Daelemans, D.; Agostinis, P.; Moens, L.; Meyts, I.
10.1101/2023.10.25.564037 — immunology — Posted on 2024-10-08
4223 Release the Krakencoder: A unified brain connectome translation and fusion tool
Jamison, K. W.; Gu, Z.; Wang, Q.; Tozlu, C.; Sabuncu, M. R.; Kuceyeski, A.
10.1101/2024.04.12.589274 — neuroscience — Posted on 2024-10-08
4224 The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion
Hollander cohen, L.; Cohen, O.; Shulman, M.; Aiznkot, T.; Fontanaud, P.; Revah, O.; Mollard, P.; Golan, M.; Levavi Sivan, B.
10.1101/2023.06.18.545454 — neuroscience — Posted on 2024-10-08
4226 Biophysically inspired mean-field model of neuronal populations driven by ion exchange mechanisms
Rabuffo, G.; Bandyopadhyay, A.; Calabrese, C.; Gudibanda, K.; Depannemaecker, D.; Takarabe, L. M.; Saggio, M. L.; Desroches, M.; Ivanov, A. I.; Linne, M.-L.; bernard, c.; Petkoski, S.; Jirsa, V.
10.1101/2021.10.29.466427 — neuroscience — Posted on 2024-10-08
4228 Plasmodesmata act as unconventional membrane contact sites regulating inter-cellular molecular exchange in plants
Smokvarska, M.; Perez-Sancho, J.; Dubois, G.; Glavier, M.; Sritharan, S.; Moraes, T. S.; Moreau, H.; Dietrich, V.; Platre, M. P.; Paterlini, A.; Li, Z. P.; Fouillen, L.; GRISON, M. S.; Cana-Quijada, P.; Immel, F.; Wattelet, V.; Ducros, M.; Brocard, L.; Chambaud, C.; Luo, Y.; Ramakrishna, P.; Bayle, V.; Legendre-Lefebvre, L.; Claverol, S.; Zabrady, M.; Busch, W.; Barberon, M.; Tilsner, J.; Helariutta, Y.; Russinova, J.; Taly, A.; Jaillais, Y.; Bayer, E.
10.1101/2023.12.18.572149 — plant biology — Posted on 2024-10-08
4229 Metastatic organotropism in small cell lung cancer
Krishnamurthy, M.; Dhall, A.; Schultz, C. W.; Baird, M. A.; Desai, P.; Odell, J.; Sahoo, S.; Takahashi, N.; Nirula, M.; Zhuang, S.; Huang, Y.; Schroeder, B.; Zhang, Y.; Thomas, M. S.; Redon, C.; Robinson, C.; Thang, L.; Ileva, L.; Patel, N. L.; Kalen, J. D.; Varlet, A.-A.; Zuela-Sopilniak, N.; Jha, A.; Wangsa, D.; Butcher, D.; Morgan, T.; Afzal, A. N.; Chari, R.; Baktiar, K.; Kumar, S.; Pongor, L.; Difilippantonio, S.; Aladjem, M. I.; Pommier, Y.; Jolly, M. K.; Lammerding, J.; Sharma, A. K.; Thomas, A.
10.1101/2024.10.07.617066 — cancer biology — Posted on 2024-10-08
4230 ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma
Bandi, D. S. R.; Ganji, P. N.; Sarvesh, S.; Carstens, J. L.; Foote, J.; Graff, E.; Fang, Y.-H. D.; Keeton, A. B.; Chen, X.; Berry, K. L.; Bae, S.; Akce, M.; Gorman, G.; Yoon, K. J.; Manne, U.; Boyd, M. R.; Buchsbaum, D. J.; Azmi, A. S.; Maxuitenko, Y. Y.; Piazza, G. A.; El-Rayes, B. F.
10.1101/2024.10.04.616725 — cancer biology — Posted on 2024-10-08
4233 Differential clearance rate of proteins encoded on a self-amplifying mRNA vaccine in muscle and lymph nodes
Kanechi, R.; Shishido, T.; Tachikawa, M.; Nishimura, T.; Sawada, A.; Okade, H.; Ishikawa, D.; Yamaguchi, H.; Araki, M.
10.1101/2024.10.07.615730 — molecular biology — Posted on 2024-10-08
4239 scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer
Huang, C.; Liu, Z.; Guo, Y.; Wang, W.; Yuan, Z.; Guan, Y.; Pan, D.; Hu, Z.; Sun, L.; Fu, Z.; Bian, S.
10.1101/2024.06.24.600356 — cancer biology — Posted on 2024-10-08
4242 Stimulus encoding shapes tactile perception and underlies alterations in autism.
Semelidou, O.; Gauvrit, T.; Vandromme, C.; Cornier, A.; Saint-Jean, A.; Le Feuvre, Y.; Ginger, M.; Frick, A.
10.1101/2024.08.08.607129 — neuroscience — Posted on 2024-10-08
4249 Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool.
Sakuragi, S.; Uchida, T.; Kato, N.; Zhao, B.; Takahashi, T.; Hattori, A.; Sakata, Y.; Soeda, Y.; Takashima, A.; Yoshimura, H.; Matsumoto, G.; Bannai, H.
10.1101/2024.05.07.592868 — biophysics — Posted on 2024-10-08
4253 SAFARI: Pangenome Alignment of Ancient DNA Using Purine/Pyrimidine Encodings
Rubin, J. D.; van Waaij, J.; Kraft, L. M.; Siren, J.; Sackett, P. W.; Renaud, G.
10.1101/2024.08.12.607489 — bioinformatics — Posted on 2024-10-08
4254 Computational design of a thermostable de novo biocatalyst for whole cell biotransformations
Elaily, W.; Stoll, D.; Chakatok, M.; Aleotti, M.; Grill, B.; Lechner, H.; Hall, M.; Oberdorfer, G.
10.1101/2024.10.07.617055 — biochemistry — Posted on 2024-10-08
4255 Estimating the effective population size across space and time in the Critically Endangered western chimpanzee in Guinea-Bissau: challenges and implications for conservation management
Ferreira da Silva, M. J.; Borges, F.; Gerini, F.; Sa, R.; Silva, F.; Maie, T.; Hernandez-Alonso, G.; Ramos-Madrigal, J.; Gopalakrishnan, S.; Aleixo-Pais, I.; Djalo, M.; Fernandes, N.; Camara, I.; Regalla, A.; Casanova, C.; Costa, M.; Colmonero-Costeira, I.; Fernandes, C. R.; Chikhi, L.; Minhos, T.; Bruford, M. W.
10.1101/2024.10.07.616982 — genomics — Posted on 2024-10-08
4257 Longhorn Beetles form Structural Colour Using Calcium Phosphate Biominerals
Chang, Y.; Tseng, H.-H.; Tanahashi, M.; Pohl, D.; Rellinghaus, B.; Bertinetti, L.; Politi, Y.
10.1101/2024.10.01.616160 — molecular biology — Posted on 2024-10-08
4258 An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research
Standeven, F. J.; Dahlquist-Axe, G.; Hendy, J.; Fiddyment, S.; Holst, M.; McGrath, K.; Collins, M.; Mundorff, A.; Radini, A.; Wagner, J.; Meehan, C. J.; Tedder, A.; Speller, C. F.
10.1101/2024.09.17.613443 — microbiology — Posted on 2024-10-08
4261 Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model for Parkinson's disease
Boeck, D.; Wilhelm, M.; Mumenthaler, J.; Carpanese, D. F.; Kulcsar, P. I.; d'Aquin, S.; Cremonesi, A.; Rassi, A.; Haberle, J.; Patriarchi, T.; Schwank, G.
10.1101/2024.03.22.586274 — neuroscience — Posted on 2024-10-08
4265 Nurseries and garden centres as hubs of alien plant invasions
Sonkoly, J.; Molnar, A.; Török, P.; Süveges, K.; Takacs, A.
10.1101/2024.10.04.616618 — ecology — Posted on 2024-10-08
4267 The biogeography of evolutionary radiations on oceanic archipelagos
Baptiste, B.; Matthews, T. J.; Fernandez-Palacios, J. M.; Paroissin, C.; Triantis, K. A.; Whittaker, R. J.; Rigal, F.
10.1101/2024.10.07.616413 — evolutionary biology — Posted on 2024-10-08
4270 The structural scaffold of the TPLATE complex deforms the membrane during plant endocytosis
Kraus, J. M.; Neubergerova, M.; Furones Cuadrado, A.; Schilling, N.; Eeckhout, D.; De Winne, N.; Van De Slijke, E.; Vandorpe, M.; Yperman, K.; Mylle, E.; Fislage, M.; De Jaeger, G.; Pleskot, R.; Van Damme, D.
10.1101/2024.10.07.616965 — plant biology — Posted on 2024-10-07
4272 Stomoxys flies (Diptera, Muscidae) are competent vectors of multiple livestock hemopathogens
Muita, J. W.; Bargul, J. L.; Makwatta, J. O.; Ngatia, E. M.; Tawich, S. K.; Masiga, D. K.; Getahun, M. N.
10.1101/2024.10.07.611962 — pathology — Posted on 2024-10-08
4274 Spatiotemporal control of a multilayered co-axial flow in a 3D printed microchannel with cascaded nozzles
Werner, H.; TaiediNejad, E.; Sahin, M. A.; Leuthner, M.; Erfle, P.; Hayden, O.; Dietzel, A.; Destgeer, G.
10.1101/2024.10.05.616779 — bioengineering — Posted on 2024-10-07
4279 Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential
Radnai, L.; Young, E. J.; Kikuti, C.; Hafenbreidel, M.; Stremel, R. F.; Lin, L.; Toth, K.; Pasetto, P.; Jin, X.; Patel, A.; Conlon, M.; Briggs, S.; Heidsleck, L.; Sweeney, L.; Sellers, J. R.; Krieger-Burke, T.; Rumbaugh, G.; Cameron, M. D.; Surman, M.; Houdusse, A.; Griffin, P. R.; Kamenecka, T. M.; Miller, C. A.
10.1101/2024.10.07.617018 — cell biology — Posted on 2024-10-07
4281 LRRK2-mutant microglia trigger dopaminergic neurodegeneration when activated by neuromelanin
Blasco-Agell, L.; Espinal, M. P.; Testa, V.; Roch, G.; Montero-Mu, J.; Fern, I.; Baruffi, V.; Gonzalez-Sepulveda, M.; Richaud-Patin, Y.; Jim, S.; Cuadros, T.; Cladera-Sastre, J. M.; Compte, J.; Otero, M. J.; Tolosa, E.; Raya, A.; Vila, M.; Consiglio, A.
10.1101/2024.10.07.616997 — cell biology — Posted on 2024-10-07
4282 Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis
Li, J.; Wang, X.; Jordana, L.; Bonneil, E.; Ginestet, V.; Ahmed, M.; Bourouh, M.; Pascariu, C. M.; Schmeing, M.; Thibault, P.; Archambault, V.
10.1101/2024.10.07.617051 — cell biology — Posted on 2024-10-07
4283 Unveiling mechanical interactions between cell division and extracellular matrix in human colonic epithelium organoids: A 4D study using DVC
Magne, L.; Pottier, T.; Michel, D.; Laussu, J.; Bonnet, D.; Alric, L.; Recher, G.; Segonds, S.; Florian, B.; Ferrand, A.
10.1101/2024.10.07.617033 — cell biology — Posted on 2024-10-07
4284 Unveiling the Crucial Role of Pro-inflammatory Macrophages in the Immune Network Imbalance of the maternal-fetal interface with Preeclampsia
Fei, H.; Lu, X.; Shi, Z.; Liu, X.; Yang, C.; Zhu, X.; Lin, Y.; Jiang, Z.; Wang, J.; Huang, D.; Liu, L.; Zhang, S.; Jiang, L.
10.1101/2024.06.05.597577 — immunology — Posted on 2024-10-08
4286 Striatal cell-type-specific molecular signatures reveal therapeutic targets in a model of dystonia
Roman, K. M.; Dinasarapu, A. R.; Cherian, S.; Fan, X.; Donsante, Y.; Aravind, N.; Chan, C. S.; Jinnah, H. A.; Hess, E. J.
10.1101/2024.10.07.617010 — neuroscience — Posted on 2024-10-07
4287 APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoids
Meyer-Acosta, K. K.; Diaz-Guerra, E.; Varma, P.; Aruk, A.; Mirsadeghi, S.; Perez, A. M.; Rafati, Y.; Hosseini, A.; Nieto-Estevez, V.; Giugliano, M.; Navara, C.; Hsieh, J.
10.1101/2024.10.07.617044 — neuroscience — Posted on 2024-10-07
4290 Neural mechanisms of the transition from planning to execution in speech production
Duraivel, K.; Rahimpour, S.; Barth, K.; Chiang, C.-H.; Wang, C.; Harward, S.; Lad, N.; Sexton, D.; Friedman, A.; Southwell, D.; Sinha, S.; Viventi, J.; Cogan, G. B.
10.1101/2024.10.07.617122 — neuroscience — Posted on 2024-10-07
4291 Local cortical inhibitory subnetworks are shaped by pyramidal neuron progenitor type
Gothard, G.; Mahfooz, K.; Newey, S. E.; Tinelli, S.; Buchan, M. J.; Burman, R. J.; Akerman, C. J.
10.1101/2024.10.07.617021 — neuroscience — Posted on 2024-10-07
4292 TAOK2 Drives Opposing Cilia Length Deficits in 16p11.2 Deletion and Duplication Carriers
Ferreccio, A.; Byeon, S.; Cornell, M.; Oses-Prieto, J. A.; Deshpande, A.; Weiss, L.; Burlingame, A.; Yadav, S.
10.1101/2024.10.07.617069 — neuroscience — Posted on 2024-10-07
4293 Oxytocin Gαi signaling-induced amygdala astrocytes processes retraction shapes behavioral stress response
Baudon, A.; Grelot, V.; Althammer, F.; Wang, K.-Y.; Denis, C.; Ali, S.; Yan, Y.; Castillo-Diaz, F.; Piacentini, F.; Creusot, E. C.; Hovhannisyan, V.; Schubert, T.; Kleinwaechter, A.; Helen, J.; Lakomy, T.; Krabichler, Q.; Derrien, P.-A.; Breton, R.; Andry, V.; Carillo-de Sauvage, M.; Demais, V.; Ces, A.; Kremer, M.; Di-Benedetto, B.; Goumon, Y.; Schaaf, C.; Grinevich, V.; Rouach, N.; Darbon, P.; Neumann, I.; Adamantidis, A.; Busnelli, M.; Benhaim, L.; Krijgsveld, J.; Pfrieger, F.; Charlet, A.
10.1101/2024.10.07.617014 — neuroscience — Posted on 2024-10-07
4294 Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
Cui, M.; Pan, X.; Fan, Z.; Wu, S.; Ji, R.; Wang, X.; Kong, X.; Wu, Z.; Song, L.; Song, W.; Yang, J.-X.; Zhang, H.; Zhang, H.; Ding, H.-L.; Cao, J.-L.
10.1101/2024.05.30.596721 — neuroscience — Posted on 2024-10-08
4296 Attention-based frontal-posterior coupling for visual consciousness in the human brain
Zhang, X.; Zhang, C.; Wu, X.; Zhou, W.; He, S.; Jiang, Y.; Zhang, K.; Wang, L.
10.1101/2024.06.30.601105 — neuroscience — Posted on 2024-10-08
4298 BEdeepon: an in silico tool for prediction of base editor efficiencies and outcomes
Zhang, C.; Yu, Z.; Wang, D.; Qi, T.; Zhang, Y.; Hou, L.; Lan, F.; Yang, J.; Shi, L.; Ong, S.-G.; Wang, H.; Wang, Y.
10.1101/2021.03.14.435303 — bioinformatics — Posted on 2024-10-08
4299 More cells, more doublets in highly multiplexed single-cell data
Howitt, G.; Dixit, G.; Aharon, R.; Streeton-Cook, V.; Ling, L.; Hickey, P. F.; Amann-Zalcenstein, D.; Gubbels, L.; Shanthikumar, S.; Ranganathan, S.; Neeland, M.; Maksimovic, J.; Oshlack, A.
10.1101/2024.10.03.616596 — bioinformatics — Posted on 2024-10-08
4301 Beyond Auditory Relay: Dissecting the Inferior Colliculus's Role in Sensory Prediction, Reward Prediction and Cognitive Decision-Making
Du, X.; Xu, H.; Song, P.; Zhai, Y.; Ye, H.; Bao, X.; Huang, Q.; Tanigawa, H.; Tu, Z.; Chen, P.; Zhao, X.; P. Rauschecker, J.; Yu, X.
10.1101/2024.07.16.603747 — neuroscience — Posted on 2024-10-08
4302 Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors.
Cabel, C. R.; Guzman, B. A.; Alizadeh, E.; Li, S.; Holberg, C.; Wichaidit, C.; Cusanovich, D. A.; Paek, A. L.; Thatcher, G. R. J.; Van Doorslaer, K.; Nargi, R. S.; Sutton, R. E.; Suryadevara, N.; Crowe, J. E.; Carnahan, R. H.; Thorne, C. A.; Campos, S. K.
10.1101/2024.10.04.616743 — pharmacology and toxicology — Posted on 2024-10-07
4303 Dual MAPK Inhibition Triggers Pro-inflammatory Signals and Sensitizes BRAF V600E Glioma to T Cell-Mediated Checkpoint Therapy
Xing, Y. L.; Grossauer, S.; Park, J.-W.; Nasajpour, E.; Bui, B.; Morales, D.; Panovska, D.; Nirschl, J. J.; Feng, Z.-P.; Wei, R.; Koeck, K.; Thomason, W.; Xiu, J.; Harter, P. N.; Filipski, K.; Mahaney, K.; Ji, X.; Mulcahy Levy, J. M.; Grant, G. A.; Prolo, L. M.; Walsh, K. M.; Lim, M.; Hambardzumyan, D.; Petritsch, C. K.
10.1101/2023.02.03.526065 — cancer biology — Posted on 2024-10-07
4305 Modeling integration site data for safety assessment with MELISSA
Lin, T.-Y.; Ceoldo, G.; House, K.; Welty, M.; Dang, T. T.; Klatt, D.; Brendel, C.; Murphy, M. P.; Cornetta, K.; Pellin, D.
10.1101/2024.09.16.613352 — bioinformatics — Posted on 2024-10-07
4306 Suspended Tissue Open Microfluidic Patterning (STOMP)
Haack, A. J.; Brown, L. G.; Goldstein, A. J.; Mulimani, P.; Berthier, J.; Viswanathan, A. R.; Kopyeva, I.; Whitten, J. M.; Lin, A.; Nguyen, S. H.; Leahy, T. P.; Bouker, E. E.; Padgett, R. M.; Mazzawi, N. A.; Tokihiro, J. C.; Bretherton, R. C.; Wu, A.; Tapscott, S. J.; DeForest, C. A.; Popowics, T. E.; Berthier, E.; Sniadecki, N. J.; Theberge, A. B.
10.1101/2024.10.04.616662 — bioengineering — Posted on 2024-10-07
4307 Computational design of a thermostable de novo biocatalyst for whole cell biotransformations
Elaily, W.; Stoll, D.; Chakatok, M.; Aleotti, M.; Grill, B.; Lechner, H.; Hall, M.; Oberdorfer, G.
10.1101/2024.10.07.617055 — biochemistry — Posted on 2024-10-07
4309 The Nucleotide Transformer: Building and Evaluating Robust Foundation Models for Human Genomics
Dalla-Torre, H.; Gonzalez, L.; Mendoza Revilla, J.; Lopez Carranza, N.; Henryk Grywaczewski, A.; Oteri, F.; Dallago, C.; Trop, E.; De Almeida, B. P.; Sirelkhatim, H.; Richard, G.; Skwark, M.; Beguir, K.; Lopez, M.; Pierrot, T.
10.1101/2023.01.11.523679 — genomics — Posted on 2024-10-07
4310 HIV Coreceptors Related Genes (CCR5 and CXCR4) Promoter Methylation: Original Research
Esman, A.; Salamaikina, S.; Vinokurov, M.; Fomina, D.; Kirichenko, A.; Sikamov, K.; Syrkina, A.; Pokrovskaya, A.; Akimkin, V.
10.1101/2024.07.01.601546 — genetics — Posted on 2024-10-07
4311 On the nature of the earliest known life forms
Kanaparthi, D.; Westall, F.; Lampe, M.; Zhu, B.; Boesen, T.; Klingl, A.; Schwille, P.; Lueders, T.
10.1101/2021.08.16.456462 — evolutionary biology — Posted on 2024-10-07
4315 Dysregulated Skeletal Muscle Myosin Super-relaxation and Energetics in Type II Diabetes
Lewis, C. T.; Moreno-Justicia, R.; Savoure, L.; Calvo, E.; Bak, A.; Laitila, J.; Seaborne, R. A. E.; Larsen, S.; Iwamoto, H.; Cefis, M.; Morais, J. A.; Gouspillou, G.; Alegre-Cebollada, J.; Hawke, T. J.; Vazquez, J.; Adrover, M.; Marcangeli, V.; Deshmukh, A. S.; Ochala, J.
10.1101/2024.06.12.598615 — cell biology — Posted on 2024-10-07
4316 Activation of Heme Metabolism Promotes Tissue Health after Intraarticular Injury or Surgical Exposure
Liman, S.; Gomez-Contreras, P. C.; Hines, M. R.; Fisher, J. S.; Lu, K. J.; McNally, L. D.; Cotoia, A. T.; Sakyi, M. Y.; Wagner, B. A.; Tift, M. S.; Goetz, J. E.; Byrne, J. D.; Coleman, M. C.
10.1101/2024.05.29.596521 — cell biology — Posted on 2024-10-07
4317 Mitochondrial DNA Release and Activation of the cGAS-STING Pathway in Lethal Stx12 Knockout Mice
Kang, J.-S.; Liu, D.-H.; li, f.; Yang, R.-Z.; Wu, Z.; Meng, X.-Y.; Li, S.-M.; Li, W.-X.; Li, J.-K.; Wang, D.-D.; Wang, R.-Y.; Li, S.-A.; Liu, P.-P.
10.1101/2024.10.07.616980 — molecular biology — Posted on 2024-10-07
4318 DNA topoisomerase I acts as supercoiling sensor for transcription elongation in E. coli
Vidmar, V.; Borde, C.; Bruno, L.; Takacs, M.; Batisse, C.; Saint-Andre, C.; Zhu, C.; Espeli, O.; Lamour, V.; Weixlbaumer, A.
10.1101/2024.10.07.617030 — molecular biology — Posted on 2024-10-07
4320 Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function
Thomas, C.; Green, S.; Kimball, L.; Schmidtke, I. R.; Rothwell, L.; Griffin, M.; Par, I.; Schobel, S.; Palacio, Y.; Towle-Weicksel, J. B.; Weicksel, S. E.
10.1101/2024.09.27.615541 — molecular biology — Posted on 2024-10-07
4321 Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages
Ma, S.; Yang, B.; Sun, Y.; Wang, X.; Guo, H.; Liu, R.; Ye, T.; Kang, C.; Chen, J.; Jiang, L.
10.1101/2024.10.07.616983 — microbiology — Posted on 2024-10-07
4322 Role of R5 Pyocin in the Predominance of High-Risk Pseudomonas aeruginosa Isolates
Zhang, L.; Xu, Q.; Tan, F. C.; Deng, Y.; Hakki, M.; Shelburne, S.; Kirienko, N.
10.1101/2024.10.07.616987 — microbiology — Posted on 2024-10-07
4324 Acquisition of daptomycin resistance in patients results in decreased virulence in Drosophila
Lamy, B.; Laurent, F.; Simoes Da silva, C. J.; Wadhawan, A. J.; Ledger, E. V. K.; Kolenda, C.; Martins Simoes, P.; Edwards, A.; Dionne, M. S.
10.1101/2024.10.07.616954 — microbiology — Posted on 2024-10-07
4326 Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens
Chac, D.; Heller, F. J.; Banna, H. A.; Kaisar, M. H.; Chowdhury, F.; Bhuiyan, T. R.; Akter, A.; Khan, A. I.; Dumayas, M. G.; Markiewicz, S. M.; Rice, A.; Karmakar, P. C.; Dash, P.; LaRocque, R. C.; Ryan, E. T.; Minot, S. S.; Harris, J. B.; Qadri, F.; Weil, A. A.
10.1101/2021.12.01.470820 — microbiology — Posted on 2024-10-07
4327 Giant virus creates subcellular environment to overcome codon-tRNA mismatch
Zhang, R.; Mayer, L.; Hikida, H.; Shichino, Y.; Mito, M.; Willemsen, A.; Iwasaki, S.; Ogata, H.
10.1101/2024.10.07.616867 — microbiology — Posted on 2024-10-07
4331 Reduced methane emissions in transgenic rice genotypes are associated with altered rhizosphere microbial hydrogen cycling
Shi, L.-D.; Ercoli, M. F.; Kim, J.; de Araujo, A. T.; Soni, S.; Weitz, T. S.; Shigenaga, A. M.; Dukovski, I.; Sachdeva, R.; Turumtay, H.; Louie, K. B.; Bowen, B. P.; Scheller, H. V.; Segre, D.; Northen, T. R.; Ronald, P. C.; Banfield, J. F.
10.1101/2024.10.07.617079 — microbiology — Posted on 2024-10-07
4337 Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle
Tomasini, C. D.; Cuche, C.; Ay, S.; Collard, M.; Cui, B.; Rashid, M.; Bhattacharjee, S.; Buchrieser, J.; Luchsinger, C.; Bertelli, C.; Uversky, V.; Diaz-Griffero, F.; Di Nunzio, F.
10.1101/2024.10.06.616889 — microbiology — Posted on 2024-10-07
4340 IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.
Derrac Soria, A.; Lewis, M. J.; Liu, X.; Twohig, J. P.; Monaco, F.; Dimonte, S.; Cardus Figueras, A.; Morrin, A.; Guy, C.; Cossins, B. C.; Benson, R.; Andrews, R.; Choy, E. H.; Garside, P.; Huwaikem, M.; Stemmler, M. P.; Brabletz, S.; Brabletz, T.; Siebzehnrubl, F. A.; Rodrigues, N. P.; Jenkins, B. J.; Pitzalis, C.; Jones, G. W.; Jones, S. A.
10.1101/2024.09.03.610972 — immunology — Posted on 2024-10-07
4343 Leveraging clinical sleep data across multiple pediatric cohorts for insights into neurodevelopment: the Retrospective Analysis of Sleep in Pediatric (RASP) cohorts study
Gong, N. N.; Mahat, A.; Ahmad, S.; Glaze, D.; Maletic-Savatic, M.; McGinley, M.; Morse, A. M.; Rodriguez, A. J.; Thurm, A.; Redline, S.; Maski, K.; Purcell, S. M.; Buckley, A.
10.1101/2024.10.04.616563 — neuroscience — Posted on 2024-10-07
4344 ML-driven design of 3' UTRs for mRNA stability
Morrow, A. K.; Thornal, A.; Flynn, E. D.; Hoelzli, E.; Shan, M.; Garipler, G.; Kirchner, R.; Reddy, A. J.; Tabchouri, S.; Gupta, A.; Michel, J.-B.; Laserson, U.
10.1101/2024.10.07.616676 — synthetic biology — Posted on 2024-10-07
4345 A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer
Foote, J.; Mattox, T. E.; Keeton, A. B.; Chen, X.; Smith, F. T.; Berry, K. L.; Holmes, T. W.; Wang, J.; Wang, C.-H.; Ward, A. B.; Mitra, A. K.; Alcantara, V. R.; Hardy, C.; Fleten, K. G.; Flatmark, K.; Yoon, K. J.; Sarvesh, S.; Nagaraju, G. P.; Bandi, D. S. R.; Maxuitenko, Y.; Valiyaveettil, J.; Carstens, J. L.; Buchsbaum, D. J.; Yang, J.; Zhou, G.; Nurmmedov, E.; Babic, I.; Gaponenko, V.; Abdelkarim, H.; Boyd, M. R.; Gorman, G. S.; Manne, U.; Bae, S.; El-Rayes, B. F.; Piazza, G. A.
10.1101/2023.05.17.541233 — cancer biology — Posted on 2024-10-07
4347 Electron Spin-Polarizability and Charge Dynamics in Ancient Polypeptides : Their Role in Protein Function
Vyas, P.; Santra, K.; Preeyanka, N.; Gupta, A.; Weil-Ktorza, O.; Zhu, Q.; Longo, L. M.; Fransson, J.; Metanis, N.; Naaman, R.
10.1101/2023.11.16.567399 — biophysics — Posted on 2024-10-07
4348 Scalable image-based visualization and alignment of spatial transcriptomics datasets
Preibisch, S.; Innerberger, M.; Leon-Perinan, D.; Karaiskos, N.; Rajewsky, N.
10.1101/2021.12.07.471629 — bioinformatics — Posted on 2024-10-07
4350 Microfluidic Modulation of Microvasculature in Microdissected Tumors
Nguyen, T. N. H.; Horowitz, L. F.; Nguyen, B.; Lockhart, E.; Zhu, S.; Gujral, T. S.; Folch, A.
10.1101/2024.09.26.615278 — bioengineering — Posted on 2024-10-07
4351 PERK Kinase Activity is Regulated by Copper Binding-A New Regulatory Paradigm for Modulation of ER Stress Tolerance
Newton, S. E. B.; Beratan, N. R.; Akay-Espinoza, C.; Bond, M. K.; Shi, X.; Perhacs, J.; Gidalevitz, T.; Brady, D. C.; Jordan-Sciutto, K. L.
10.1101/2022.09.02.506340 — biochemistry — Posted on 2024-10-07
4352 A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis.
Raia, P.; Lee, K.; Bartsch, S. M.; Rico-Resendiz, F.; Portugal-Calisto, D.; Vadas, O.; Panse, V. G.; Fiedler, D.; Hothorn, M.
10.1101/2024.09.12.612650 — biochemistry — Posted on 2024-10-07
4354 Structural extension of the human exocyst is enabled by a minimal interface
Xu, H. D.; Badonyi, M.; Sopipong, W.; MacGowan, S. A.; Marsh, J. A.; Murray, D. H.
10.1101/2024.10.07.617058 — biochemistry — Posted on 2024-10-07
4355 Evidence for biomolecular condensates of MatP in spatiotemporal regulation of the bacterial cell division cycle
Barros-Medina, I.; Robles-Ramos, M. A.; Sobrinos-Sanguino, M.; Luque-Ortega, J. R.; Alfonso, C.; Margolin, W.; Rivas, G.; Monterroso, B.; Zorrilla, S.
10.1101/2024.07.23.604758 — biochemistry — Posted on 2024-10-07
4356 Structural and molecular basis of FAN1 defects in promoting Huntington's disease
Pluciennik, A.; Li, F.; Phadte, A. A.; Bhatia, M.; Barndt, S.; Monte Carlo, A. R.; Hou, C.-f. D.; Yang, R.; Strock, S.
10.1101/2024.10.07.617005 — biochemistry — Posted on 2024-10-07
4358 A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs
Buckley, R. M.; Bilgen, N.; Harris, A. C.; Savolainen, P.; Tepeli, C.; Erdogan, M.; Serres Armero, A.; Dreger, D. L.; van Steenbeek, F. G.; Hytönen, M. K.; Hale, J.; Lohi, H.; Cınar Kul, B.; Boyko, A. R.; Ostrander, E. A.
10.1101/2024.10.04.616687 — genomics — Posted on 2024-10-07
4365 GenomicGapID: Leveraging Spatial Distribution of Conserved Genomic Sites for Broad-Spectrum Microbial Identification
Asthana, V.; Bugga, P.; Smith, C.; Wellman, C.; Dwight, Z.; Ranjan, P.; Nieves, E. M.; Dickson, R. P.; VanEpps, J. S.
10.1101/2024.10.07.617038 — microbiology — Posted on 2024-10-07
4366 Effects of excess phosphate on a coastal plankton community: a mesocosm experiment in the Baltic Sea
Spilling, K.; Vanharanta, M.; Santoro, M.; Villena-Alemany, C.; Labrenz, M.; Grossart, H.-P.; Piwosz, K.
10.1101/2024.02.05.576994 — microbiology — Posted on 2024-10-07
4369 FungAMR: A comprehensive portrait of antimicrobial resistance mutations in fungi
Bedard, C.; Pageau, A.; Fijarczyk, A.; Mendoza-Salido, D.; Alcaniz, A.; Despres, P.; Durand, R.; Plante, S.; Alexander, E.; Rouleau, F.; Giguere, M.; Bernier, M.; Sharma, J.; Maroc, L.; Gervais, N.; Menon, A.; Gagnon-Arsenault, I.; Bakker, S.; Rhodes, J.; Dufresne, P.; Bharat, A.; Sellam, A.; De Luca, D.; Gerstein, A.; Shapiro, R.; Quijada, N.; Landry, C.
10.1101/2024.10.07.617009 — microbiology — Posted on 2024-10-07
4374 Dopamine and temporal discounting: revisiting pharmacology and individual differences
Smith, E.; Theis, H.; van Eimeren, T.; Knauth, K.; Tuzsus, D.; Zhang, L.; Mathar, D.; Peters, J.
10.1101/2024.08.28.610170 — neuroscience — Posted on 2024-10-07
4376 Outer hair cells stir cochlear fluids
Lee, C.; Shokrian, M.; Henry, K. S.; Carney, L.; Holt, J. C.; Nam, J.-H.
10.1101/2024.08.07.607009 — neuroscience — Posted on 2024-10-07
4377 Location of NMDARs and co-agonist controls the generation of bursts in nigral dopamine neurons
Ringlet, S.; Motta, Z.; Vandries, L.; Seutin, V.; Jehasse, K.; Caldinelli, L.; Pollegioni, L.; Engel, D.
10.1101/2024.06.06.597701 — neuroscience — Posted on 2024-10-07
4379 Structure of the human CTF18 clamp loader bound to PCNA
Briola, G.; Tehseen, M.; Al-Amodi, A.; Nguyen, P. Q.; Savva, C. G.; Hamdan, S. M.; De Biasio, A.
10.1101/2024.05.08.593111 — biochemistry — Posted on 2024-10-07
4381 HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1
Serrano, T.; Casartelli, N.; Ghasemi, F.; Wioland, H.; Cuvelier, F.; Salles, A.; Moya-Nilges, M.; Welker, L.; Bernacchi, S.; Ruff, M.; Jegou, A.; Romet-Lemonne, G.; Schwartz, O.; Fremont, S.; Echard, A.
10.1101/2024.10.07.616958 — cell biology — Posted on 2024-10-07
4382 Nutri Complex 150+: a new and effective approach to facial rejuvenation
Privitera, A.; Ferruggia, G.; Contino, M.; Maugeri, S.; Zimbone, M.; Cardile, V.; Caruso, G.; Brundo, M. V.
10.1101/2024.10.05.616805 — cell biology — Posted on 2024-10-07
4383 A Method for Electrical Stimulus Artifact Removal Exploiting Neural Refractoriness: Validation by Contrasting Cathodic and Anodic Stimulation
Nakhmani, A.; Block, J.; Awad, M.; Olson, J.; Smith, R. J.; Bentley, N. J.; Holland, M. T.; Brinkerhoff, S. A.; Gonzalez, C. L.; Moffitt, M.; Walker, H. C.
10.1101/2024.10.06.616879 — bioengineering — Posted on 2024-10-07
4384 The arrival of the Near Eastern ancestry in Central Italy predates the onset of the Roman Empire
Ravasini, F.; Conati Barbaro, C.; Scheib, C. L.; Tambets, K.; Metspalu, M.; Cruciani, F.; Trombetta, B.; D'Atanasio, E.
10.1101/2024.10.07.617003 — genomics — Posted on 2024-10-07
4385 Unveiling the Origins and Genetic Makeup of the 'Forgotten People': A Study of the Sarmatian-Period Population in the Carpathian Basin
Schütz, O.; Maroti, Z.; Tihanyi, B.; Kiss P, A.; Nyerki, E.; Ginguta, A.; Kiss, P.; Varga, G. I. B.; Kovacs, B.; Maar, K.; Kovacsoczy Ny., B.; Lukacs, N.; Major, I.; Marcsik, A.; Patyi, E.; Szigeti, A.; Toth, Z.; Walter, D.; Wilhelm, G.; Andrasi Cs., R.; Bernert, Z.; Kis, L.; Ota, L.; Palfi, G.; Pintye, G.; Popity, D.; Simalcsik, A.; Soficaru, A. D.; Spekker, O.; Varga, S.; Neparaczki, E.; Török, T.
10.1101/2024.10.04.616652 — genetics — Posted on 2024-10-07
4386 Glacier Retreat Effects On Ecosystem Development And Carbon Dynamics
Ceresa, E.; Casallas, L. M. V.; Charles, C.; Grand, S.; Losapio, G.
10.1101/2024.10.06.616884 — ecology — Posted on 2024-10-07
4387 Exploring the Educational Potential of Instagram in the New Generations: A Study on the Impact of "Adopt a Bacterium"
Rodrigues Cintra Armellini, B.; Nardi Baroni, L.; Carvalho Maia Brito, S.; Ramos Moreno, A. C.; de Souza, R. F.; Lellis-Santos, C.; Cafe Ferreira, R. d. C.
10.1101/2024.10.01.616198 — microbiology — Posted on 2024-10-07
4390 Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depression
Zhu, H.; Tong, X.; Carlisle, N. B.; Xie, H.; Keller, C. J.; Oathes, D. J.; Nemeroff, C. B.; Fonzo, G. A.; Zhang, Y.
10.1101/2024.10.04.616707 — neuroscience — Posted on 2024-10-07
4392 Turgor limitation of tree height: no evidence from leaf epidermal cell anatomy
Aleman-Sancheschulz, G.; Olson, M. E.; Rosell, J.; Salgado-Ugarte, I.; Perez-Maussan, I.
10.1101/2024.10.06.616874 — plant biology — Posted on 2024-10-07
4394 Mapping the niche of breast cancer metastases in lung and liver
Sznurkowska, M. K.; Castro-Giner, F.; Zhang, Y.; Ring, A.; Schwab, F. D.; Albrecht, F.; Mertz, K. D.; Strittmatter, K.; Ozimski, L. L.; Budinjas, S.; Auray, G.; Giachino, C.; Taylor, V.; Gvozdenovic, A.; Malanchi, I.; Frauchiger-Heuer, H.; Wicki, A.; Vetter, M.; Aceto, N.
10.1101/2024.10.04.616491 — cancer biology — Posted on 2024-10-07
4395 Zebrafish Avatar-test predicts patient's tumor response to chemotherapy in breast cancer: a co-clinical study towards personalized medicine
Mendes, R. V.; Ribeiro, J.; Gouveia, H.; Almeida, C. R. d.; Castillo-Martin, M.; Brito, M. J.; Canas-Marques, R.; Batista, E.; Alves, C.; Sousa, B.; Gouveia, P.; Ferreira, M. G.; Cardoso, M. J.; Cardoso, F.; Fior, R.
10.1101/2024.10.03.616349 — cancer biology — Posted on 2024-10-07
4397 Profiling drug sensitivity of leukemic stem cells via bulk-to-single-cell deconvolution
Alexandre, C.; Forey, R.; Bejar Haro, B.; Martins, F.; Carlevaro-Fita, J.; Sheppard, S.; Offner, S. E.; La Manno, G.; Obozinski, G.; Trono, D.
10.1101/2023.05.10.540140 — bioinformatics — Posted on 2024-10-07
4398 Insights into Heart Failure Metabolite Markersthrough Explainable Machine Learning
Baron, C.; Mehanna, P.; Daneault, C.; Hausermann, L.; Busseuil, D.; Tardif, J.-C.; Dupuis, J.; Des Rosiers, C.; Ruiz, M.; Hussin, J.
10.1101/2024.10.04.616718 — bioinformatics — Posted on 2024-10-07
4402 Ketamine reverses chronic stress-induced behavioral changes via the expression of Ca2+-permeable AMPA receptors in mice
Flowers, J. C.; Vetter, P. E.; Wiles, M. J.; Roh, S. H.; Black, E. R.; Bouckova, E.; Wustrau, M. H.; Lee, R.; Lee, S.-H.; Kim, S.
10.1101/2024.10.07.616991 — neuroscience — Posted on 2024-10-07
4404 Presynaptic filopodia form kinapses and modulate membrane mechanics for synchronous neurotransmission and seizure generation.
Jain, A.; Kroll, J.; Webster, J. F.; Moss, J.; Ultanir, S. K.; Gonzalez-Sulser, A.; Rosenmund, C.; Cousin, M. A.; Ivanova, D.
10.1101/2024.10.07.616970 — neuroscience — Posted on 2024-10-07
4405 Regional deficits in endogenous regeneration of mouse olfactory sensory neuron axons
Kunkhyen, T.; Curtis, K. A.; Deakin, T. P.; Huang, J. S.; Gregory, J. D.; Cheetham, C. E. J.
10.1101/2024.10.06.616907 — neuroscience — Posted on 2024-10-07
4406 Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates
Lindquist, K.; Mecklenburg, J. M.; Hovhannisyan, A. H.; Ruparel, S.; Akopian, A. N.
10.1101/2024.10.06.616876 — neuroscience — Posted on 2024-10-07
4408 Separate timescales for spatial and anatomical information processing during action observation
Baptiste, W. M.; McAteer, S.; Moreno-Verdu, M.; Van Caenegem, E. E.; Du, Y.; Hardwick, R. M.
10.1101/2024.10.07.616993 — neuroscience — Posted on 2024-10-07
4409 Neuropeptide-dependent spike time precision and plasticity in circadian output neurons
Chong, B.; Kumar, V.; Nguyen, D. L.; Hopkins, M. A.; Spera, L. K.; Paul, E. M.; Hutson, A. N.; Tabuchi, M.
10.1101/2024.10.06.616871 — neuroscience — Posted on 2024-10-07
4413 Complex slow waves radically reorganise human brain dynamics under 5-MeO-DMT
Blackburne, G.; McAlpine, R. G.; Fabus, M.; Liardi, A.; Kamboj, S. K.; Mediano, P. A. M.; Skipper, J. I.
10.1101/2024.10.04.616717 — neuroscience — Posted on 2024-10-07
4415 Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness
Fotiadis, P.; McKinstry-Wu, A. R.; Weinstein, S. M.; Cook, P. A.; Elliott, M.; Cieslak, M.; Duda, J. T.; Satterthwaite, T. D.; Shinohara, R. T.; Proekt, A.; Kelz, M. B.; Detre, J. A.; Bassett, D. S.
10.1101/2024.10.04.616650 — neuroscience — Posted on 2024-10-07
4419 Animal acoustic communication maintains a universal optimum rhythm
Piette, T.; Cathcart, C.; Barbieri, C.; Martin Ming, K.; Grandjean, D.; Bickel, B.; Deaux, E.; Giraud, A.-L.
10.1101/2024.10.07.616955 — animal behavior and cognition — Posted on 2024-10-07
4424 Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae
Priego-Cubero, S.; Knoch, E.; Wang, Z.; Alseekh, S.; Braun, K. H.; Chapman, P.; Fernie, A. R.; Liu, C.; Becker, C.
10.1101/2024.10.02.615186 — plant biology — Posted on 2024-10-07
4425 TSST-1 promotes colonization of Staphylococcus aureus within the vaginal tract by activation of CD8+T cells
Dufresne, K.; Al, K. F.; Craig, H. C.; Coleman, C. E. M.; Kasper, K. J.; Burton, J. P.; McCormick, J. K.
10.1101/2024.10.04.616698 — microbiology — Posted on 2024-10-07
4426 Pathological PNPase variants with altered RNA binding and degradation activity affect the phenotype of bacterial and human cell models
Pizzoccheri, R.; Falchi, F. A.; Alloni, A.; Caldarulo, M.; Camboni, T.; Zambelli, F.; Pavesi, G.; Visentin, C.; Camilloni, C.; Sertic, S.; Briani, F.
10.1101/2024.10.03.616462 — genetics — Posted on 2024-10-07
4427 A Mycobacterium tuberculosis secreted virulence factor disrupts host snRNP biogenesis
Chauhan, K.; Passricha, N.; Kapoor, Y.; Datta, D.; Arora, N.; Das, M.; Rao, K.; Singh, L.; Dutt, R.; Sharma, R.; Sarkar, B.; Malakkar, B.; Saini, P.; Mehra, L.; Das, P.; Ahuja, V.; Singhal, A.; Nandicoori, V.; Kumar, D.
10.1101/2024.02.06.579120 — molecular biology — Posted on 2024-10-07
4430 Universal rules govern plasmid copy number
Ramiro-Martinez, P.; de Quinto, I.; Gama, J. A.; Rodriguez-Beltran, J.
10.1101/2024.10.04.616648 — microbiology — Posted on 2024-10-07
4435 Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets
Papaiakovou, M.; Waeschenbach, A.; Ajibola, O.; Ajjampur, S. S.; Anderson, R. M.; Bailey, R.; Benjamin Chung, J.; Cambra Pelleja, M.; Caro, N. R.; Chaima, D.; Cimino, R. O.; Cools, P.; Cossa, A.; Dunn, J.; Galagan, S.; Gandasegui, J.; Grau Pujol, B.; Houlder, E.; Ibikounle, M.; Jenkins, T. P.; Kalua, K.; Kjetland, E. F.; Krolewiecki, A. J.; Levecke, B.; Luty, A. J.; MacDonald, A.; Mandomando, I.; Manuel, M.; Martinez Valladares, M.; Mejia, R.; Mekonnen, Z.; Messa, A.; Mpairwe, H.; Muchisse, O.; Munoz, J.; Mwinzi, P.; Novela, V.; Odiere, M. R.; Sacoor, C.; Walson, J. L.; Williams, S. A.; Witek
10.1101/2024.09.23.614419 — genomics — Posted on 2024-10-07
4439 The GLP-1 analogue, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice
Mermet, M.; Denom, J.; Mieczkowska, A.; Biggs, E.; Gribble, F. M.; Reimann, F.; Magnan, C.; Cruciani-Guglielmacci, C.; Mabilleau, G.
10.1101/2024.10.05.616809 — physiology — Posted on 2024-10-06
4441 Inhibition of pterygium cell fibrosis by the Rho kinase inhibitor
Dai, J.; Rayana, N. P.; Peng, M.; Sugali, C. K.; Harvey, D. H.; Dhamodaran, K.; Yu, E.; Liu, S.; Mao, W.
10.1101/2024.10.05.616834 — pharmacology and toxicology — Posted on 2024-10-06
4442 Extracellular vesicles from a novel chordoma cell line, ARF-8, promote tumorigenic microenvironmental changes when incubated with the parental cells and with human osteoblasts.
Nguyen, K. N.; Graner, A. N.; Fringuello, A. R.; Zizzo, Z.; Valenzuela, L.; Anyanwu, K.; Lillehei, K. O.; Youssef, A. S.; Guzman, S.; Coughlan, C.; Graner, M. W.
10.1101/2024.10.06.616873 — cancer biology — Posted on 2024-10-06
4450 A shared code for perceiving and imagining objects in human ventral temporal cortex
Wadia, V. S.; Reed, C. M.; Chung, J. M.; Bateman, L. M.; Mamelak, A. N.; Rutishauser, U.; Tsao, D. Y.
10.1101/2024.10.05.616828 — neuroscience — Posted on 2024-10-06
4451 Molecular logic for cellular specializations that initiate the auditory parallel processing pathways
Jing, J.; Hu, M.; Ngodup, T.; Ma, Q.; Lau, S. N. N.; Ljungberg, C.; McGinley, M. J.; Trussell, L. O.; Jiang, X.
10.1101/2023.05.15.539065 — neuroscience — Posted on 2024-10-06
4453 Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease
Seo, B. A.; Kwon, S.-H.; Kim, D.; Kim, H.-B.; Ma, S.-X.; Gadhave, K.; Burgess, N.; Mao, X.; Rosenthal, L. S.; Redding-Ochoa, J.; Troncoso, J. C.; Lee, S.; Dawson, V. L.; Dawson, T. M.; Ko, H.
10.1101/2024.02.19.580982 — neuroscience — Posted on 2024-10-06
4460 Targeting DNA-PK is a highly conserved poxvirus innate immune evasion mechanism
Oliveira, M.; Manna, P. T.; Rodrigues, D.; Allport, T.; Wagner, E.; Brooks, H.; Skinner, M. A.; Giotis, E. S.; Chaplin, A. K.; Guabiraba, R.; Bryant, C. E.; Ferguson, B. J.
10.1101/2024.10.06.616852 — immunology — Posted on 2024-10-06
4463 Effects of temperature on the life-history traits of Myzus persicae and its efficiency in transmitting potato virus Y (PVY) in potato crops
Sokame, B. M.; Tonnang, H. E.; Gamarra, H. A.; Carhuapoma, P.; Kreuze, J. F.; Arab, A.; Armbruster, P. A.; Johnson, L. R.; Villena, O. C.
10.1101/2024.10.05.616836 — plant biology — Posted on 2024-10-06
4464 Hydrothermal pretreatment renders peat susceptible to enzymatic saccharification
Thomsen, J.; Lett, S.; Martens, H.; Sorensen, H.; Kelleher, D.; Tryfona, T.; Dupree, P.; Johansen, K. S.
10.1101/2024.10.05.616816 — plant biology — Posted on 2024-10-06
4466 Endogenous Huntingtin aggregates are a huge organized scaffold and mold for Golgi apparatus impaired by mutant Huntingtin protein
Ma, L.; Chen, X.; Liu, Y.; Dai, L. l.; Yang, W.; Buhe, H.; Ma, J.; Song, C.; Li, L.; Fan, d.; Su, J.; saiyin, H.
10.1101/2024.10.06.616845 — pathology — Posted on 2024-10-06
4467 Collective amoeboid dynamics drives colonization of drug-resistant ovarian cancer cells
Goutham, S.; Gopikrishnan, A.; BV, H.; Venas, N.; Sabarinathan, R.; Jolly, M. K.; Bhat, R.
10.1101/2024.10.05.616763 — cancer biology — Posted on 2024-10-06
4468 Tau accelerates tubulin exchange in the microtubule lattice
Biswas, S.; Grover, R.; Reuther, C.; Poojari, C.; Shaebani, M. R.; Grünewald, M.; Zablotsky, A.; Hub, J. S.; Diez, S.; John, K.; Schaedel, L.
10.1101/2024.10.05.616777 — biophysics — Posted on 2024-10-06
4470 ProteinAligner: A Multi-modal Pretraining Framework for Protein Foundation Models
Zhang, L.; Guo, H.; Schaffer, L. V.; Ko, Y. S.; Singh, D.; Rahmani, H.; Grotjahn, D.; Villa, E.; Gilson, M.; Wang, W.; Ideker, T.; Xing, E.; Xie, P.
10.1101/2024.10.06.616870 — bioinformatics — Posted on 2024-10-06
4473 Rapid and cost-effective production of high-quality insect genome sequences
Gilligan, J.; Inwood, S. N.; Harrop, T. W. R.; Keddell, P.; McPhail, K.; Sproston, C. J.; Williams, D. W.; Petersen, G.; Hovius, A.; Kaspar, J.; Guhlin, J. G.; Dearden, P.
10.1101/2024.10.06.616902 — genomics — Posted on 2024-10-06
4474 An ancient lysozyme in placozoans
Berndt, H.; Duarte, I.; Repnik, U.; Struwe, M.; Abukhalaf, M.; Scheidig, A.; Tholey, A.; Gruber-Vodicka, H.; Leippe, M.
10.1101/2024.10.06.616844 — evolutionary biology — Posted on 2024-10-06
4475 Genomic and evolutionary evidence for drought adaptation of grass allopolyploid Brachypodium hybridum
Wang, Y.; Chen, G.; Zeng, F.; Deng, F.; Yang, Z.; Han, Z.; Xu, S.; Nevo, E.; Catalan, P.; Chen, Z.-H.
10.1101/2024.10.06.616847 — evolutionary biology — Posted on 2024-10-06
4477 Land-use changes impact root-fungal network connectivity in a global biodiversity hotspot
Carneiro de Melo Moura, C.; Guerrero-Ramirez, N. R.; Krashevska, V.; Polle, A.; Siregar, I. Z.; Ballauff, J.; Siregar, U. J.; Encinas-Viso, F.; Bell, K.; Nevill, P.; Gailing, O.
10.1101/2024.10.05.616733 — ecology — Posted on 2024-10-06
4479 Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway
Riedelbauch, S.; Masser, S.; Fasching, S.; Lin, S.-Y.; Salgania, H. K.; Aarup, M.; Ebert, A.; Jeske, M.; Levine, M. T.; Stelzl, U.; Andersen, P.
10.1101/2024.10.05.616775 — molecular biology — Posted on 2024-10-06
4481 Inhibitors of dihydroorotate dehydrogenase synergize with the broad antiviral activity of 4'-fluorouridine
Schrell, L.; Fuchs, H. L.; Dickmanns, A.; Scheibner, D.; Olejnik, J.; Hume, A. J.; Reineking, W.; Stoerk, T.; Mueller, M.; Graaf-Rau, A.; Diederich, S.; Finke, S.; Baumgaertner, W.; Muhlberger, E.; Balkema-Buschmann, A.; Dobbelstein, M.
10.1101/2024.10.05.616778 — microbiology — Posted on 2024-10-06
4484 Novel Mechanism of Inflammatory Activation by Ebola Virus Matrix Protein Linked to the Ebolavirus Virulence
Yamaoka, S.; MHamdi, Z.; Wang, L.; Swenson, V. A.; McNally, K. L.; Lu, S.-C.; Singh, R.; Saundh, S. L.; Zell, B. N.; Best, S. M.; Barry, M. A.; Rasmussen, A. L.; Ebihara, H.
10.1101/2024.10.06.616882 — microbiology — Posted on 2024-10-06
4485 Genetic Adaptation to Amoxicillin in Escherichia coli: The Limited Role of dinB and katE
Teichmann, L. H.; Wenne, M.; Luitwieler, S. H.; Dugar, G. H.; Bengtsson-Palme, J.; ter Kuile, B. H.
10.1101/2024.10.05.616818 — microbiology — Posted on 2024-10-06
4487 Faecalibacterium prausnitzii induces an anti-inflammatory response and a metabolic reprogramming in human monocytes
Danne, C.; Creusot, L.; de Oliveira Formiga, R.; Marquet, F.; Sedda, D.; Hua, L.; Ruffie, P.; Pham, H.-P.; Salgueiro, I. A.; Brot, L.; Michel, M.-L.; Langella, P.; Lefevre, J.; Sokol, H.; ROLHION, N.
10.1101/2024.10.06.616495 — immunology — Posted on 2024-10-06
4488 Self-assembly of hybrid 3D cultures by integrating living and synthetic cells
Piernitzki, N.; Gao, N.; Gasparoni, G.; Schulze-Hentrich, J.; Dustin, M. L.; Gyoerffy, B.; Mann, S.; Staufer, O.
10.1101/2024.10.05.616774 — synthetic biology — Posted on 2024-10-06
4489 De novo design of α-helical peptide channels with designer stoichiometry
Niitsu, A.; Thomson, A.; Scott, A. J.; Sengel, J. T.; Jung, J.; KR, M.; Sodeoka, M.; Bayley, H.; Sugita, Y.; Woolfson, D. N.; Wallace, M. I.
10.1101/2024.10.05.616771 — synthetic biology — Posted on 2024-10-06
4490 Mapping the PTEN Mutation Landscape: Structural and Functional Drivers of Lung Cancer
Hossain, M. U.; Sakib, M. N.; Rahman, A. B. Z. N.; Hasan, S. S.; Nisha, N. H.; Bhattacharjee, A.; Chowdhury, Z. M.; Ahammad, I.; Das, K. C.; Rahman, M. S.; Salimullah, M.
10.1101/2024.10.06.616856 — cancer biology — Posted on 2024-10-06
4491 Loss of the Inv(16) Oncogene CBFB::MYH11 Eliminates Leukemia from the Blood and Spleen, but not the Bone Marrow
Panda, S.; Wang, Y.; Becker, M.; Dhir, A.; Lam, C.; Rivas, C.; Alemu, L.; Garrett, L.; Swenson, S.; Hyde, R. K.
10.1101/2024.10.06.616896 — cancer biology — Posted on 2024-10-06
4494 P450-Catalyzed Biaryl Macrocyclization of Leaderless Ribosomal Peptides
Liu, R.; Ren, H.; Wu, G.; He, B.; Pang, C.; Shen, Z.; Liu, J.; Zhiman, S.; Zhou, J.; Li, Y.-x.
10.1101/2024.10.06.616194 — biochemistry — Posted on 2024-10-06
4499 Gene encoding CC-NBS-LRR protein on rye chromosome 1RS confers wheat stripe rust resistance
Han, F.; Wang, C.; Chang, Y.; Wang, M.; Wang, J.; Liu, C.; Fan, C.; Yi, C.; Zhou, C.; Yuan, J.; Yang, W.; Liu, D.; Wang, T.; Liu, Y.; Ye, X.
10.1101/2024.10.04.616747 — genetics — Posted on 2024-10-06
4503 Identification of a new Plasmodium falciparum E2 ubiquitin conjugating enzyme
Smith, C.; Hajisadeghian, M.; van der Heden van Noort, G. J.; Pinto-Fernandez, A.; Kessler, B. M.; Artavanis-Tsakonas, K.
10.1101/2024.10.06.616869 — cell biology — Posted on 2024-10-06
4504 The TWEAK/Fn14 signaling promotes skeletal muscle wasting during cancer cachexia
Tomaz da Silva, M.; Roy, A.; Vuong, A. T.; Joshi, A. S.; Josphien, C.; Trivedi, M. V.; Hindi, S. M.; Narkar, V. A.; Kumar, A.
10.1101/2024.10.06.616866 — cell biology — Posted on 2024-10-06
4511 Growth-coupled microbial biosynthesis of the animal pigment xanthommatin
Bushin, L. B.; Alter, T. B.; Alvan-Vargas, M. V. G.; Dürr, L.; Olson, E. C.; Avila, M. J.; Puiggene, O.; Kim, T.; Deravi, L. F.; Feist, A. M.; Nikel, P. I.; Moore, B. S.
10.1101/2024.10.04.616593 — synthetic biology — Posted on 2024-10-06
4512 Wheat stripe rust resistance gene Yr9, derived from rye, is a CC-NBS-LRR gene in a highly conserved NLR cluster
Yu, Y.; Liu, J.; Lan, S.; Chen, Q.; Li, J.; Song, H.; Pan, C.; Qi, J.; Ni, F.; Epstein, L.; Fu, D.; Wu, J.
10.1101/2024.10.04.616745 — plant biology — Posted on 2024-10-06
4516 Malaria parasite HOPS/CORVET complexes are critical for endocytosis and invasion organelles function
Mesen-Ramirez, P.; Fuchs, G.; Burmester, J.; Farias, G. B.; Alape-Flores, A.-M.; Singla, S.; Alder, A.; Cubillan-Marin, J.; Castro-Pena, C.; Lemcke, S.; Sondermann, H.; Prado, M.; Spielmann, T.; Wilson, D. W.; Gilberger, T.-W.
10.1101/2024.10.04.616647 — cell biology — Posted on 2024-10-06
4517 An updated map of the trypanosome nuclear pore and its associated proteins
Gabiatti, B. P.; Krenzer, J.; Braune, S.; Krüger, T.; Zoltner, M.; Kramer, S.
10.1101/2024.10.04.616621 — cell biology — Posted on 2024-10-06
4518 Genetic diversity and population structure of soybean (Glycine max (L.) Merril) germplasm.
SILUE, T.; Agre, P. A.; Olasanmi, B.; Adewumi, A. S.; Adejumobi, I. I.; Abebe, A. T.
10.1101/2024.10.02.616345 — molecular biology — Posted on 2024-10-06
4519 Streptococcus pneumoniae with biosynthesis gene mutations attenuate disease but retain their potential for epithelial microinvasion and epithelial innate immune activation
Weight, C. M.; Pollara, G. M.; Betts, M.; Ragazzini, R.; Connor, M.; Ramos-Sevillano, E.; Reine, J.; Whelan, M.; Guerra-Assuncao, J. A.; Bonfanti, P.; Jolly, C.; Noursadeghi, M.; Ferreira, D.; Brown, J.; Heyderman, R. S.
10.1101/2023.06.15.545009 — microbiology — Posted on 2024-10-06
4522 Continuous cell type diversification throughout the embryonic and postnatal mouse visual cortex development
Gao, Y.; van Velthoven, C. T. J.; Lee, C.; Thomas, E. D.; Bertagnolli, D.; Carey, D.; Casper, T.; Chakka, A. B.; Chakrabarty, R.; Clark, M.; Desierto, M. J.; Ferrer, R.; Gloe, J.; Goldy, J.; Guilford, N.; Guzman, J.; Halterman, C. R.; Hirschstein, D.; Ho, W.; James, K.; McCue, R.; Meyerdierks, E.; Nguy, B.; Pena, N.; Pham, T.; Shapovalova, N. V.; Sulc, J.; Torkelson, A.; Tran, A.; Tung, H.; Wang, J.; Ronellenfitch, K.; Levi, B.; Hawrylycz, M. J.; Pagan, C.; Dee, N.; Smith, K. A.; Tasic, B.; Yao, Z.; Zeng, H.
10.1101/2024.10.02.616246 — neuroscience — Posted on 2024-10-06
4529 Novel insights into IKur modulation by Lgi3-4: Implications in atrial fibrillation
Socuellamos, P. G.; Macias, A.; de Benito-Bueno, A.; Cruz, F. M.; Redondo-Moya, M.; Coronado, M. J.; Ramil, E.; Rosado, S.; Rios-Rosado, E. C.; Valencia-Avezuela, M.; de Andres-Delgado, L.; Blazquez Gonzalez, J. A.; Forteza-Gil, A.; Gutierrez-Rodriguez, M.; Jalife, J.; Valenzuela, C.
10.1101/2024.10.03.616587 — physiology — Posted on 2024-10-06
4530 Age-induced BMP signaling inhibits the ICAT-mediated Wnt pathway to promote osteoarthritis.
Kumar, B.; Iqbal, S. F.; Jena, A.; Arora, S.; Gupta, P.; Thaleshwari, S.; Taketo, M. M. M.; Bandyopadhyay, A.
10.1101/2024.10.02.616036 — pathology — Posted on 2024-10-06
4531 p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners
Brdar, A.; Osterburg, C.; Münick, P.; Machel, A. C.; Rathore, R.; Osterburg, S.; Yüksel, B.; Schäfer, B.; Desch, K.; Langer, J. D.; Dikic, I.; Dötsch, V.
10.1101/2024.10.02.616239 — biophysics — Posted on 2024-10-06
4537 PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment.
Sarkar, B.; Singh, J.; Yadav, M.; Sharma, P.; Sharma, R. D.; Singh, S.; Chandramouli, A.; Mehdiratta, K.; Kumar, A.; Kamat, S. S.; Ghorpade, D. S.; Mohanty, D.; Kumar, D.; Gokhale, R. S.
10.1101/2024.02.02.578554 — microbiology — Posted on 2024-10-06
4539 Genetically encoded biosensor for fluorescence lifetime imaging of PTEN dynamics in the intact brain
Kagan, T.; Gabay, M.; Levi, Y.; Eid, S.; Malchenko, N.; Maman, M.; Nitzan, A.; Ravotto, L.; Zaidel-Bar, R.; Gal, M.; Laviv, T.
10.1101/2024.10.04.616644 — neuroscience — Posted on 2024-10-06
4544 Novel diagnosis- and progression-related microRNA signatures in melanoma
Gomez-Martinez, H.; Gomez-Cabanes, B.; Galiana-Rosello, C.; Virues Morales, A.; Dolader Rabinad, B.; del Rey Diez, N.; Lopez-Cerdan, A.; Hernando, E.; Garcia-Garcia, F.
10.1101/2023.10.20.563284 — cancer biology — Posted on 2024-10-06
4546 Additive and partially dominant effects from genomic variation contribute to rice heterosis
Dan, Z.; Chen, Y.; Zhou, W.; Xu, Y.; Huang, J.; Chen, Y.; Meng, J.; Yao, G.; Huang, W.
10.1101/2024.07.16.603817 — plant biology — Posted on 2024-10-06
4547 DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis
Trasierras-Fresco, A. M.; Virues-Morales, A.; Gomez-Martinez, H.; Dolader Rabinad, B.; del Rey Diez, N.; Andreu, Z.; Hidalgo, M. R.; Gomez-Cabanes, B.; Poley Gil, M.; Malmierca-Merlo, P.; Romera-Giner, S.; Crespo, D.; Serna-Blasco, R.; Romero, A.; Lopez-Guerrero, J. A.; de la Iglesia Vaya, M.; Garcia-Garcia, F.
10.1101/2022.10.15.512358 — cancer biology — Posted on 2024-10-06
4549 gRNAde: Geometric Deep Learning for 3D RNA inverse design
Joshi, C. K.; Jamasb, A. R.; Vinas, R.; Harris, C.; Mathis, S. V.; Morehead, A.; Anand, R.; Lio, P.
10.1101/2024.03.31.587283 — bioinformatics — Posted on 2024-10-06
4553 Universal Cell Embeddings: A Foundation Model for Cell Biology
Rosen, Y.; Roohani, Y.; Agrawal, A.; Samotorcan, L.; Consortium, T. S.; Quake, S. R.; Leskovec, J.
10.1101/2023.11.28.568918 — cell biology — Posted on 2024-10-06
4554 Transcriptomic Insights into Hypothalamic Aging During Menopause: A Comparative Analysis of Human and Mouse Models
Bloom, J. C. B.; Torres, E.; Pereira, S. A.; Arvizu-Sanchez, L.; Fontes, A. N.; Joffe, H.; Page, D. C.; Navarro, V. M.
10.1101/2024.10.05.616758 — neuroscience — Posted on 2024-10-06
4555 A shared code for perceiving and imagining objects in human ventral temporal cortex
Wadia, V. S.; Reed, C. M.; Chung, J. M.; Bateman, L. M.; Mamelak, A. N.; Rutishauser, U.; Tsao, D. Y.
10.1101/2024.10.05.616828 — neuroscience — Posted on 2024-10-06
4559 A 3D Image Segmentation Study of U-Net on CT Images of the Human Aorta with Morphologically Diverse Anatomy
Chen, J.; Qian, L.; Wang, P.; Sun, C.; Qin, T.; Kalyanasundaram, A.; Zafar, M.; Elefteriades, J.; Sun, W.; Liang, L.
10.1101/2024.10.02.616348 — bioengineering — Posted on 2024-10-05
4563 Deep Mining of the Human Antibody Repertoire Identifies Frequent and Immunogenetically Diverse CDRH3 Topologies Targetable by Vaccination
Habib, R.; Solieva, S. O.; Lin, Z. J.; Ghosh, S.; Bayruns, K.; Singh, M.; Agostino, C. J.; Tursi, N. J.; Sowers, K. J.; Huang, J.; Roark, R. S.; Purwar, M.; Park, Y.; Ayyanathan, K.; Li, H.; Carey, J. W.; Kim, A.; Park, J.; McCanna, M. E.; Skelly, A. N.; Chokkalingam, N.; Kriete, S.; Shupin, N.; Huynh, A.; Walker, S.; Laenger, N.; Du, J.; Cui, J.; Hahn, B. H.; Patel, A.; Escolano, A.; Kwong, P. D.; Shapiro, L.; Bowman, G. R.; Shaw, G. M.; Weiner, D. B.; Pallesen, J.; Kulp, D. W.
10.1101/2024.10.04.616739 — immunology — Posted on 2024-10-05
4565 Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbiota-gut-brain axis of zebrafish in a sex-specific and dosage-dependent manner
Abi Assaf, J.; de Coriolis, J.-C.; Godden, A. M.; Redhead, E.; Bartram, J.; Cohen-Krais, J.; Silova, K.; Crighton, Z.; Le Gall, G.; Sami, S.; Khalid, S. A.; Immler, S.
10.1101/2024.10.04.616708 — systems biology — Posted on 2024-10-05
4566 ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma
El-Rayes, B. N.; Bandi, D. S. R.; Ganji, P. N.; Sarvesh, S.; Carstens, J. L.; Foote, J.; Graff, E.; Fang, Y.-H. D.; Keeton, A. B.; Chen, X.; Berry, K. L.; Bae, S.; Akce, M.; Gorman, G.; Yoon, K. J.; Manne, U.; Boyd, M. R.; Buchsbaum, D. J.; Azmi, A. S.; Maxuitenko, Y. Y.; Piazza, G. A.
10.1101/2024.10.04.616725 — cancer biology — Posted on 2024-10-05
4571 The effect of population size on adaptation to fluctuating temperatures
Räsänen, E.; Nieminen, V.; Summanen, P. A. M.; Villalba de la Pena, M.; Makkonen, P.; Suisto, K.; Ketola, T.; Kronholm, I.
10.1101/2024.10.05.616761 — evolutionary biology — Posted on 2024-10-05
4572 Testing for the genomic footprint of conflict between life stages in an angiosperm and a moss species
Yuan, M.; Kollar, L. M.; Sacchi, B. M.; Carey, S. B.; Choudhury, B. I.; Jones, T.; Grimwood, J.; Barrett, S. C.; McDaniel, S. F.; Wright, S. I.; Stinchcombe, J. R.
10.1101/2024.10.04.613734 — evolutionary biology — Posted on 2024-10-05
4574 C-Reactive Protein Drives Potent Clearance of Blood Bacteria in the Liver by Activating the Complement System
Chen, D.; Hu, J.; Zhu, M.; Xie, Y.; Yao, H.; An, H.; Meng, Y.; Wang, J.; Huang, X.; Shao, Z.; Xiang, Y.; Qi, J.; Gao, G. F.; Zhang, J.-R.
10.1101/2024.10.05.616753 — immunology — Posted on 2024-10-05
4575 Comprehensive sequencing of the lung neuroimmune landscape in response to asthmatic induction
McSwiggin, H.; Wang, R.; Magalhaes, R. D. M.; Zhu, F.; Doherty, T. A.; Yan, W.; Jendzjowsky, N.
10.1101/2024.10.04.616730 — immunology — Posted on 2024-10-05
4576 An iterative design approach to development of an ex-vivo normothermic multivisceral perfusion platform
van Leeuwen, L. L.; Holzner, M. L.; McKenney, C.; Todd, R.; Frost, J. K.; Gudibendi, S.; Kim-Schluger, L.; Schiano, T.; Florman, S.; Akhtar, M. Z.
10.1101/2024.10.04.616696 — physiology — Posted on 2024-10-05
4577 Suppression of NRF2-dependent cancer growth by a covalent allosteric molecular glue
Roy, N.; Wyseure, T.; Lo, I.-C.; Metzger, J.; Eissler, C. L.; Bernard, S. M.; Bok, I.; Snead, A. N.; Parker, A.; Green, J. C.; Inloes, J.; Jacinto, S. R.; Kuenzi, B.; Horning, B. D.; Ibrahim, N.; Grabow, S.; Panda, H.; Bhatt, D. P.; Saeidi, S.; Zolkind, P.; Rush, Z.; Negri, K.; Williams, H. N.; Walton, E.; Pastuszka, M. K.; Sigler, J. J.; Tran, E.; Hee, K.; McLaughlin, J.; Ambrus-Aikelin, G.; Pollock, J.; Abraham, R. T.; Kinsella, T. M.; Simon, G. M.; Major, M. B.; Weinstein, D. S.; Patricelli, M. P.
10.1101/2024.10.04.616592 — cancer biology — Posted on 2024-10-05
4583 Ixochymostatin, a trypsin inhibitor-like (TIL) protein from Ixodes scapularis, inhibits chymase and impairs vascular permeability
Almeida Martins, L.; Berger, M.; Kotal, J.; Lu, S.; Sousa-Paula, L. C.; Smith, B. J.; Zhang, Y.; Andersen, J. F.; Tirloni, L.
10.1101/2024.10.04.616518 — biochemistry — Posted on 2024-10-05
4584 Structural Basis for the Improved RNA-Clamping of Amidino-Rocaglates to eIF4A1
Conley, J. F.; Brown, L. E.; McNeeley, J. H.; Pelletier, J.; Porco, J. A.; Allen, K. N.
10.1101/2024.10.04.616674 — biochemistry — Posted on 2024-10-05
4585 Intrinsic molecular identifiers enable robust molecular counting in single-cell sequencing
Fontanez, K.; Agam, Y.; Bevans, S.; May-Zhang, A.; Hayford, C.; Xue, Y.; Ishibashi, J. S. A.; Komuhendo, R.; Yoder, L.; Hettige, P.; Rickner, H.; Zhang, J. Q.; D'Amato, C.; Smithers, T.; Osman, A.; Calkins, S.; Rahman, M.; Mutafopulos, K. S.; Kiani, S.; Meltzer, R. H.
10.1101/2024.10.04.616561 — genomics — Posted on 2024-10-05
4586 Defining a tandem repeat catalog and variation clusters for genome-wide analyses and population databases
Weisburd, B.; Dolzhenko, E.; Bennett, M. F.; Danzi, M. C.; English, A.; Hiatt, L.; Tanudisastro, H.; Kurtas, N. E.; Jam, H. Z.; Brand, H.; Sedlazeck, F. J.; Gymrek, M.; Dashnow, H.; Eberle, M. A.; Rehm, H. L.
10.1101/2024.10.04.615514 — genomics — Posted on 2024-10-05
4590 Gut Bacteria Encode Reductases that Biotransform Steroid Hormones
Arp, G.; Jiang, A.; Dufault-Tompson, K.; Levy, S.; Zhong, A.; Wassan, J. T.; Grant, M.; Li, Y.; Hall, B.; Jiang, X.
10.1101/2024.10.04.616736 — microbiology — Posted on 2024-10-05
4592 Siglec-F Deficiency Prevents Fibrosis After Bleomycin-Induced Acute Lung Injury
Orlov, M.; Rangarajan, S.; Jaramillo, A. M.; Ye, Q.; Hara, N.; Ngo, K.; NeeDell, J. C.; Harder, A. Q.; Jia, F.; Vestal, B.; Blumhagen, R. Z.; Tu, T.-H.; McClendon, J.; McCubbrey, A. L.; Smith, B. J.; Schwartz, D. A.; Janssen, W. J.; Evans, C. M.
10.1101/2024.10.04.616703 — physiology — Posted on 2024-10-05
4593 Tag with Caution - How protein tagging influences the formation of condensates
D/"orner, K.; Gut, M.; Overwijn, D.; Cao, F.; Siketanc, M.; Heinrich, S.; Beuret, N.; Sharpe, T.; Lindorff-Larsen, K.; Hondele, M.
10.1101/2024.10.04.616694 — molecular biology — Posted on 2024-10-05
4595 Human and Mouse Models for Kabuki Syndrome Reveal Increase in Inhibitory Synapse Development.
Knopp, J.; Weaver, A.; Miller, S.; Nomura, T.; Whitlark, A.; Swantkowski, J.; Noble, A.; Nam, S.; Hutson, K.; Bergqvist-Patzke, J.; Contractor, A.; Patzke, C.
10.1101/2024.10.04.616738 — neuroscience — Posted on 2024-10-05
4601 Suspended Tissue Open Microfluidic Patterning (STOMP)
Haack, A. J.; Brown, L. G.; Goldstein, A. J.; Mulimani, P.; Berthier, J.; Viswanathan, A. R.; Kopyeva, I.; Whitten, J. M.; Lin, A.; Nguyen, S. H.; Leahy, T. P.; Bouker, E. B.; Padgett, R. M.; Mazzawi, N. A.; Tokihiro, J. C.; Bretherton, R. C.; Wu, A.; Tapscott, S. J.; DeForest, C. A.; Popowics, T. E.; Berthier, E.; Sniadecki, N. J.; Theberge, A. B.
10.1101/2024.10.04.616662 — bioengineering — Posted on 2024-10-05
4602 Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease
Seo, B. A.; Kwon, S.-H.; Kim, D.; Kim, H.-B.; Ma, S.-X.; Gadhave, K.; Burgess, N.; Mao, X.; Rosenthal, L. S.; Redding-Ochoa, J.; Troncoso, J. C.; Lee, S.; Dawson, V. L.; Dawson, T. M.; Ko, H.
10.1101/2024.02.19.580982 — neuroscience — Posted on 2024-10-05
4605 Extensive distribution of β-1,2-glucanases: finding of new glycoside hydrolase families of β-1,2-glucanases
Nakajima, M.; Tanaka, N.; Motouchi, S.; Kobayashi, K.; Shimizu, H.; Abe, K.; Hosoyamada, N.; Abara, N.; Morimoto, N.; Hiramoto, N.; Nakata, R.; Takashima, A.; Hosoki, M.; Suzuki, S.; Shikano, K.; Fujimaru, T.; Imagawa, S.; Kawadai, Y.; Wang, Z.; Kitano, Y.; Nihira, T.; Nakai, H.; Taguchi, H.
10.1101/2024.02.06.578578 — biochemistry — Posted on 2024-10-05
4608 Complete sequencing of ape genomes
Yoo, D.; Rhie, A.; Hebbar, P.; Antonacci, F.; Logsdon, G. A.; Solar, S. J.; Antipov, D.; Pickett, B. D.; Safonova, Y.; Montinaro, F.; Luo, Y.; Malukiewicz, J.; Storer, J. M.; Lin, J.; Sequeira, A. N.; Mangan, R. J.; Hickey, G.; Anez, G. M.; Balachandran, P.; Bankevich, A.; Beck, C. R.; Biddanda, A.; Borchers, M.; Bouffard, G. G.; Brannan, E.; Brooks, S. Y.; Carbone, L.; Carrel, L.; Chan, A. P.; Crawford, J.; Diekhans, M.; Engelbrecht, E.; Feschotte, C.; Formenti, G.; Garcia, G. H.; Gennaro, L. d.; Gilbert, D.; Green, R. E.; Guarracino, A.; Gupta, I.; Haddad, D.; Han, J.; Harris, R. S.; Hartley
10.1101/2024.07.31.605654 — genomics — Posted on 2024-10-05
4612 Scaling laws of plasmids across the microbial tree of life
Maddamsetti, R.; Wilson, M. L.; Son, H.-I.; Zhou, Z.; Lu, J.; You, L.
10.1101/2024.10.04.616653 — microbiology — Posted on 2024-10-05
4613 Disruption of riboflavin biosynthesis in mycobacteria establishes 5-amino-6-D-ribitylaminouracil (5-A-RU) as key precursor of MAIT cell agonists
Chengalroyen, M. D.; Oketade, N.; Worley, A.; Lucas, M.; Ramirez, L. N.; Raphela, M. L.; Swarbrick, G.; Warner, D. F.; Lewinsohn, D.; Mehaffy, C.; Adams, E. J.; Hildebrand, W.; Dobos, K. M.; Mizrahi, V.; Lewinsohn, D.
10.1101/2024.10.03.616430 — immunology — Posted on 2024-10-05
4615 MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor
Sohail, I.; Laurin, S.-A.; Kleinau, G.; Chunilal, V.; Morton, A.; Kagiali, Z. C. U.; Tello, J. A.; Lohse, M. J.; Scheerer, P.; Bouvier, M.; McCormick, P.; Annibale, P.; Biebermann, H.
10.1101/2024.04.09.588099 — pharmacology and toxicology — Posted on 2024-10-05
4618 Superior colliculus projections drive dopamine neuron activity and movement but not value
Poisson, C. L.; Wolff, A. R.; Prohofsky, J.; Herubin, C.; Blake, M. T.; Saunders, B. T.
10.1101/2024.10.04.616744 — neuroscience — Posted on 2024-10-05
4620 Investigation of cellular and molecular changes linked with neuropathic pain in healthy and injured human trigeminal nerves
Morchio, M.; Sankaranarayanan, I.; Tavares-Ferreira, D.; Wong, N.; Atkins, S.; Sher, E.; Price, T. J.; Lambert, D.; Boissonade, F. M.
10.1101/2024.10.05.616798 — neuroscience — Posted on 2024-10-05
4624 Heterogeneous distribution of inhibitory inputs among motor units as a key mechanism for motor adaptations to pain
Hug, F.; Dernoncourt, F.; Avrillon, S.; Thorstensen, J.; Besomi, M.; van den Hoorn, W.; Tucker, K.
10.1101/2024.10.05.616762 — neuroscience — Posted on 2024-10-05
4625 Haematobiochemical Alterations and Lesion Characterization Induced by Haemonchosis in Sheep Slaughtered at Gondar ELFORA Abattoir, North West Ethiopia
Malede, B. A.; Kebede, M. C.; Berihun, A. M.; Mekonnen, M. Y.; Yesuf, M.; Mitiku, T.; Birhan, M.; Kenubih, A.; Temesgen, A. B.
10.1101/2024.10.03.616054 — pathology — Posted on 2024-10-05
4627 Representation of Verbal Thought in Motor Cortex and Implications for Speech Neuroprostheses
Kunz, E. M.; Meschede-Krasa, B.; Kamdar, F.; Avansino, D.; Nason-Tomaszewski, S. R.; Card, N. S.; Jacques, B.; Bechefsky, P.; Hahn, N.; Iacobacci, C.; Hochberg, L. R.; Brandman, D. M.; Stavisky, S. D.; Yong, N. A.; Pandarinath, C.; Druckmann, S.; Henderson, J. M.; Willett, F. R.
10.1101/2024.10.04.616375 — neuroscience — Posted on 2024-10-05
4630 Monosynaptic ventral tegmental area glutamate projections to the locus coeruleus enhance aversive processing
Parker, K. E.; Kuo, C.-C.; Buckley, A. R.; Patterson, A. P.; Duong, V.; Hunter, S. C.; McCall, J. G.
10.1101/2024.10.04.615025 — neuroscience — Posted on 2024-10-05
4631 Mammalian chemosensory bile acid detection supports species and gut microbiome evaluation
Haran, V.; Morimoto, M.; Rouyer, L. S. F.; McDonald, J. G.; Wang, J.; Meeks, J. P.
10.1101/2024.10.04.616633 — neuroscience — Posted on 2024-10-05
4632 Cholinergic regulation of sleep in the upside-down jellyfish Cassiopea
Abrams, M. J.; Ohdera, A. H.; Francis, D. A.; Donayre, O.; Chen, H.; Lu, K. Y.; Harland, R. M.
10.1101/2024.10.04.616757 — animal behavior and cognition — Posted on 2024-10-05
4634 Localized synthesis of molecular chaperones sustains neuronal proteostasis
Alecki, C.; Rizwan, J.; Le, P.; Jacob-Tomas, S.; Fernandez-Comaduran, M.; Verbrugghe, M.; Xu, J. S. M.; Minotti, S.; Lynch, J.; Biswas, J.; Wu, T.; Durham, H.; Yeo, G. W.; Vera, M.
10.1101/2023.10.03.560761 — molecular biology — Posted on 2024-10-05
4635 ASSESSMENT OF THE IMPACT OF SLEEP DEPRIVATION AND DIET ON GROWTH, COGNITION, INFLAMMATION, OXIDATIVE STRESS, AND TISSUE HISTOLOGY
Usman, L. A.; Ajani, E. O.; Akinmoladun, A. C.; Ibrahim, R. B.; Oyedeji, B. R.; Adedotun, T. A.; Mustapha, G. A.; Abdulwahab, R. Y.; Banuso, A. I.; Oyedokun, O. O.; Olatunji, A. R.; Akande, K. A.; Oni, O. G.; Oduola, O.; Oguntayo, O. B.; Saka, D. K.; Hussain, A.-H. O.
10.1101/2024.10.04.616642 — neuroscience — Posted on 2024-10-05
4638 Trans-generational adaptation to maternal climate through hormone transport in plants
Chen, X.; Bezodis, W.; Gonzalez-Suarez, P.; Knitlhoffer, V.; Goldson, A.; Lister, A.; Macaulay, I.; Penfield, S.
10.1101/2024.10.04.616646 — plant biology — Posted on 2024-10-05
4639 Heterogeneity in chromatin structure drives core regulatory pathways in B-cell Acute Lymphoblastic Leukemia
Sen, A.; Xu, Z.; Tyndale, S.; Yasis, J.; Cho, C. Y.; Bump, R.; Chandran, S.; Luo, L.; Fu, Y.; Petersen, L. K.; Shokhirev, M.; Kuo, D. J.; McVicker, G. P.; Dixon, J. R.
10.1101/2024.10.04.616668 — cancer biology — Posted on 2024-10-05
4641 Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition
Lee, J.-H.; Thomsen, M.; Daub, H.; Thieulin-Pardo, G.; Steinbacher, S. C.; Sztyler, A.; Dahiya, V.; Neudegger, T.; Dominguez, C.; Iyer, R. R.; Wilkinson, H. A.; Monteagudo, E.; Plotnikov, N. V.; Felsenfeld, D. P.; Haque, T. S.; Finley, M.; Boudet, J.; Vogt, T. F.; Prasad, B. C.
10.1101/2023.05.08.539930 — biophysics — Posted on 2024-10-05
4642 Estimating wingbeat frequency on hummingbirds by using a no-labeling learning computer vision approach
Bastidas-Rodriguez, M. X.; Fernandes, A. M.; Espejo Uribe, M. J.; Abaunza, D.; Roncancio, J. S.; Gutierrez Zamora, E. A.; Florez Pai, C.; Smiley, A.; Hurme, K. M.; Clark, C. J.; Rico-Guevara, A.
10.1101/2024.10.04.616678 — bioinformatics — Posted on 2024-10-05
4643 Image-based force inference by biomechanical simulation
Vanslambrouck, M.; Thiels, W.; Vangheel, J.; van Bavel, C.; Smeets, B.; Jelier, R.
10.1101/2023.12.01.569682 — bioinformatics — Posted on 2024-10-05
4649 α-Copaene is a potent repellent against the Asian Citrus Psyllid Diaphorina citri
Magnani, R. F.; Volpe, H. X. L.; Luvizotto, R. A. G.; Mulinari, T. A.; Agostini, T. T.; Bastos, J. K.; Ribeiro, V. P.; Carmo-Sousa, M.; Wulff, N. A.; Pena, L.; Leal, W.
10.1101/2024.10.04.616677 — ecology — Posted on 2024-10-05
4650 Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer factor-mediated zygotic genome activation
Marsh, A. J.; Pirogov, S.; Ruffridge, A. J.; Sajwan, S.; Gibson, T. J.; Hunt, G.; Kaur, Y.; Harrison, M. M.; Mannervik, M.
10.1101/2024.10.04.616638 — developmental biology — Posted on 2024-10-05
4651 Microtubule forces drive nuclear damage in LMNA cardiomyopathy
Amiad Pavlov, D.; Heffler, J.; Corredera, C. S.; Dehghany, M.; Shen, K. M.; Zuela-Sopilniak, N.; Randell, R.; Uchida, K.; Jain, R.; Shenoy, V.; Lammerding, J.; Prosser, B. L.
10.1101/2024.02.10.579774 — cell biology — Posted on 2024-10-05
4652 Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis
Joshi, A. S.; Castillo, M. B.; Tomaz da Silva, M.; Vuong, A. T.; Gunaratne, P. H.; Darabi, R.; Liu, Y.; Kumar, A.
10.1101/2024.06.03.597179 — cell biology — Posted on 2024-10-05
4653 Melanocyte differentiation and mechanosensation are differentially modulated by distinct extracellular matrix proteins
Luthold, C.; Didion, M.; Benedum, E.; Burkhart, A.-K.; Demmerle, N.; Gunaratnam, G.; Racz, V. S.; Bischoff, M.; Ridzal, A.; Iden, S.
10.1101/2024.10.04.616635 — cell biology — Posted on 2024-10-05
4654 Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification
Fruchard, L.; Babosan, A.; Carvalho, A.; Lang, M.; Li, B.; Duchateau, M.; Giai Gianetto, Q.; Matondo, M.; Bonhomme, F.; Hatin, I.; Arbes, H.; Fabret, C.; Corler, E.; Sanchez, G.; MArchand, V.; Motorine, Y.; NAMY, O.; de Crecy-Lagard, V.; Mazel, D.; Baharoglu, Z.
10.1101/2022.09.26.509455 — microbiology — Posted on 2024-10-05
4655 A ubiquitous and diverse methanogenic community drives microbial methane cycling in eutrophic coastal sediments
Wallenius, A. J.; Venetz, J.; Zygadlowska, O. M.; Lenstra, W. K.; van Helmond, N. A. G. M.; Dalcin Martins, P.; Slomp, C. P.; Jetten, M. S. M.
10.1101/2024.10.04.616656 — microbiology — Posted on 2024-10-05
4657 Scaling laws of plasmids across the microbial tree of life
Maddamsetti, R.; Wilson, M. L.; Son, H.-I.; Zhou, Z.; Lu, J.; You, L.
10.1101/2024.10.04.616653 — microbiology — Posted on 2024-10-05
4660 Leveraging clinical sleep data across multiple pediatric cohorts for insights into neurodevelopment: the Retrospective Analysis of Sleep in Pediatric (RASP) cohorts study
Gong, N. N.; Mahat, A.; Ahmad, S.; Glaze, D.; Maletic-Savatic, M.; McGinley, M.; Morse, A. M.; Rodriguez, A. J.; Redline, S.; Maski, K.; Purcell, S. M.; Buckley, A.
10.1101/2024.10.04.616563 — neuroscience — Posted on 2024-10-05
4661 Why do we have so many excitatory neurons?
Wang, Q.; Cardona, A.; Zlatic, M.; Vogelstein, J.; Priebe, C.
10.1101/2024.09.24.614724 — neuroscience — Posted on 2024-10-05
4662 Unsigned temporal difference errors in cortical L5 dendrites during learning
Schoenfeld, G.; Kollmorgen, S.; Tsai, M. C.; Lewis, C. M.; Han, S.; Bethge, P.; Reuss, A. M.; Aguzzi, A.; Senn, W.; Mante, V.; Helmchen, F.
10.1101/2021.12.28.474360 — neuroscience — Posted on 2024-10-05
4663 Motor Imagery Enhances Performance Beyond the Imagined Action
Gippert, M.; Shih, P.-C.; Heed, T.; Howard, I. S.; Jamshidi Idaji, M.; Villringer, A.; Sehm, B.; Nikulin, V.
10.1101/2024.10.04.616651 — neuroscience — Posted on 2024-10-05
4664 Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
Cui, M.; Pan, X.; Fan, Z.; Wu, S.; Ji, R.; Wang, X.; Kong, X.; Wu, Z.; Song, L.; Song, W.; Yang, J.-X.; Zhang, H.; Zhang, H.; Ding, H.-L.; Cao, J.-L.
10.1101/2024.05.30.596721 — neuroscience — Posted on 2024-10-05
4667 HBN-EEG: The FAIR implementation of the Healthy Brain Network (HBN) electroencephalography dataset
Shirazi, S. Y.; Franco, A.; Scopel Hoffmann, M.; Esper, N.; Truong, D.; Delorme, A.; Milham, M.; Makeig, S.
10.1101/2024.10.03.615261 — neuroscience — Posted on 2024-10-05
4668 Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity
Xiong, Y.; Tan, L.; Chan, W.-k.; Yin, E.; Donepudi, S. R.; Ding, J.; Wei, B.; Tran, B.; Martinez, S.; Mahmud, I.; Stewart, H.; Hermanson, D.; Weinstein, J. N.; Lorenzi, P. L.
10.1101/2024.09.25.615060 — systems biology — Posted on 2024-10-05
4671 Evolution of plant cell-type-specific cis-regulatory elements
Yan, H.; Mendieta, J. P.; Zhang, X.; Marand, A. P.; Liang, Y.; Luo, Z.; Minow, M. A. A.; Jang, H.; Li, X.; Roule, T.; Wagner, D.; Tu, X.; Wang, Y.; Jiang, D.; Zhong, S.; Huang, L.; Wessler, S. R.; Schmitz, R. J.
10.1101/2024.01.08.574753 — plant biology — Posted on 2024-10-05
4672 The FIP 1.0 Data Set: Highly Resolved Annotated Image Time Series of 4,000 Wheat Plots Grown in Six Years
Roth, L.; Boss, M.; Kirchgessner, N.; Aasen, H.; Aguirre-Cuellar, B. P.; Akiina, P. P. A.; Anderegg, J.; Gajardo Castillo, J.; Chen, X.; Corrado, S.; Cybulski, K.; Keller, B.; Kortstee, S. G.; Kronenberg, L.; Liebisch, F.; Nousi, P.; Oppliger, C.; Perich, G.; Pfeifer, J.; Yu, K.; Storni, N.; Tschurr, F.; Volpi, M.; Treier, S.; Zellweger, H.; Zumsteg, O.; Hund, A.; Walter, A.
10.1101/2024.10.04.616624 — plant biology — Posted on 2024-10-05
4673 A curve fitting method for analysing starch granule size distributions in cereals
McNelly, R.; Briffa, A.; Yiasoumi, G.; Uauy, C.; Matsushima, R.; Seung, D.
10.1101/2024.10.03.616408 — plant biology — Posted on 2024-10-05
4674 Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction
Hara, N.; Raclawska, D. S.; Morgan, L. E.; Needell, J. C.; Dao, L.; Kato, A.; Jaramillo, A. M.; Hume, P. S.; Holguin, F.; Janssen, W. J.; Vladar, E. K.; Evans, C. M.
10.1101/2024.05.10.593580 — physiology — Posted on 2024-10-05
4675 An active matter model captures the spatial dynamics of actomyosin oscillations during morphogenesis
Mackay, E. D.; Bebbington, A.; Januschke, J.; Kursawe, J.; Bischoff, M.; Sknepnek, R.
10.1101/2024.10.04.616649 — biophysics — Posted on 2024-10-05
4681 Application of modular isoxazoline-β2,2-amino acid-based peptidomimetic foldamers as a chemical model system for studying the tau misfolding mechanism.
Di Lorenzo, D.; Bisi, N.; Bucci, R.; Ennen, I.; Lo Presti, L.; Dodero, V.; Brandt, R.; ONGERI, S.; Gelmi, M. L.; Tonali, N.
10.1101/2024.10.04.616679 — biochemistry — Posted on 2024-10-05
4688 The within-subject stability of cortical thickness, surface area, and brain volumes across one year
Wang, M.-Y.; Korbmacher, M.; Eikeland, R.; Nerland, S.; Vidal-Pineiro, D.; Specht, K.
10.1101/2024.06.01.596956 — neuroscience — Posted on 2024-10-05
4695 SATB2 and circ3915 RNA chromatin dysregulation drive KRAS-like oncogenic transformation
Eleazer, R.; George, S.; Shoemaker, L.; Saintilnord, W.; Lau, K.; Chandler, D.; Fondufe-Mittendorf, Y.
10.1101/2024.10.04.616681 — cancer biology — Posted on 2024-10-04
4698 Long deletion signatures in repetitive genomic regions track somatic evolution and enable sensitive detection of microsatellite instability
Guo, Q.; Househam, J.; Lakatos, E.; Nowinski, S.; Al Bakir, I.; Grant, H.; Balarajah, V.; Hughes, C. S.; Zapata, L.; Kocher, H.; Sottoriva, A.; Baker, A.-M.; Mustonen, V.; Graham, T.
10.1101/2024.10.03.616572 — bioinformatics — Posted on 2024-10-04
4700 Exploring the Potential of Malvidin and Echiodinin as Probable Antileishmanial Agents Through In Silico Analysis And In Vitro Efficacy
Goyzueta-Mamani, L. D.; Pagliara Lage, D.; Barazorda-Ccahuana, H. L.; Paco-Chipana, M. I.; Candia-Puma, M. A.; Davila-Del-Carpio, G. H.; Sobreira Galdino, A.; Machado-de-Avila, R. A.; Cordeiro Giunchetti, R.; D'Antonio, E.; Ferraz Coelho, E. A.; Chavez-Fumagalli, M. A.
10.1101/2024.10.04.616659 — bioinformatics — Posted on 2024-10-04
4701 Aging at scale: Younger dogs and larger breeds from the Dog Aging Project show accelerated epigenetic aging.
McCoy, B. M.; Mariner, B. L.; Cheng, C. F.; Silkas, E.; Adjangba, C.; Greenier, A.; Brassington, L.; Marye, A.; Harrison, B. R.; Partida-Aguilar, M.; Bamberger, T.; Algavi, Y.; Muller, E.; Harris, A.; Rout, E.; Avery, A.; Promislow, D.; Borenstein, E.; The Dog Aging Project Consortium, ; Snyder-Mackler, N.
10.1101/2024.10.03.616519 — genomics — Posted on 2024-10-04
4702 Interspecies hybridization as a route of accessory chromosome origin in fungal species infecting wild grasses
Fagundes, W. C.; Moeller, M.; Feurtey, A.; Hansen, R.; Haueisen, J.; Salimi, F.; Alizadeh, A.; Stukenbrock, E. H.
10.1101/2024.10.03.616481 — evolutionary biology — Posted on 2024-10-04
4706 Impact of JN.1 booster vaccination on neutralisation of SARS-CoV-2 variants KP.3.1.1 and XEC
Arora, P.; Happle, C.; Kempf, A.; Nehlmeier, I.; Stankov, M. V.; Dopfer-Jablonka, A.; Behrens, G. M. N.; Poehlmann, S.; Hoffmann, M.
10.1101/2024.10.04.616448 — molecular biology — Posted on 2024-10-04
4708 Early Postnatal Dysfunction of mPFC PV Interneurons in Shank3B-/- Mice
Peixoto, R. T.; Shih, Y.-C.; Nelson, L.; Janecek, M.; Matarazzo, M.
10.1101/2024.10.04.616584 — neuroscience — Posted on 2024-10-04
4711 Systems genetic dissection of Alzheimer's disease brain gene expression networks
Zhao, P.; El Fadel, O.; Le, A.; Mangleburg, C. G.; Dhindsa, J.; Wu, T.; Zhao, J.; Huang, M.; Amoh, B.; Marella, A. S.; Li, Y.; Seyfried, N. T.; Levey, A. I.; Liu, Z.; Al Ramahi, I.; Botas, J.; Shulman, J. M.
10.1101/2024.10.04.616661 — systems biology — Posted on 2024-10-04
4713 A new spatial multi-omics approach to deeply characterize human cancer tissue using a single tissue section
Adimi, Y.; Levin, C.; Lombardi, E. P.; Morin, B.; Gervais, C.; Tolou, S.; Noirot-Jagu, A.-C.; Hauret, J.; Thomas, C.; Tchepikoff, P.; Grigorev, F.; Djafri, A.; Longuemaux, S.; Caron, A.; Naimi, S.; Cesaroni, M.; Tartour, E.; Classe, M.; Badoual, C.
10.1101/2024.10.03.616510 — cancer biology — Posted on 2024-10-04
4715 Temporal multi-modal single-cell analyses reveal dynamic interactions of CAR-T cells with glioblastoma and targeting of antigen-negative neoplastic cells
Zhang, D. Y.; Wang, X.; Sun, Y.; Cui, Q.; Nelson, E.; Zhang, Z.; Huang, B.; Giles, J.; Thokala, R.; Connolly, D. R.; Jacob, F.; Wherry, J.; Lucas, T.; Chen, I. H.; Shi, Y.; Binder, Z. A.; Brem, S.; Nasrallah, M.; Salinas, R.; O'Rourke, D. M.; Ming, G.-L.; Song, H.
10.1101/2024.10.03.616537 — cancer biology — Posted on 2024-10-04
4716 APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer
Cramer, Z.; Monaghan, K.; Petroni, R.; Wang, X.; Adams, S.; Durning, K.; Kim, M.; Tian, Y.; Johnson, N.; Leu, N. A.; Sidoli, S.; Li, N.; Blanco, M. A.; Lengner, C.
10.1101/2024.10.03.616482 — cancer biology — Posted on 2024-10-04
4717 Mechanical constraints organize 3D tissues and orchestrate muscle differentiation
Nagle, I.; van der Spek, L.; Gesenhues, P.; Savy, T.; Rea, L.; Richert, A.; Receveur, M.; Delort, F.; Batonnet-Pichon, S.; Wilhelm, C.; Luciani, N.; Reffay, M.
10.1101/2024.10.03.616457 — biophysics — Posted on 2024-10-04
4718 Computational Analysis of the Binding Poses of Nitazene Derivatives at the mu-Opioid Receptor
Clayton, J.; Shi, L.; Skiniotis, G.; Robertson, M. J.; Michaelides, M.; Stavitskaya, L.; Shen, J.
10.1101/2024.10.03.616560 — biophysics — Posted on 2024-10-04
4719 Stress-hardening behaviour of biofilm streamers
Savorana, G.; Redaelli, T.; Truzzolillo, D.; Cipelletti, L.; Secchi, E.
10.1101/2024.10.04.616620 — biophysics — Posted on 2024-10-04
4721 Beyond planar: fish schools adopt ladder formations in 3D
Ko, H.; Girma, A.; Zhang, Y.; Pan, Y.; Lauder, G.; Nagpal, R.
10.1101/2024.10.03.616549 — biophysics — Posted on 2024-10-04
4723 A browser-based platform for storage, visualization, and analysis of large-scale 3D images in HPC environments
Walker, L. A.; Lee, W. J.; Duan, B.; Weatherspoon, M.; Li, Y.; Shen, F. Y.; Cheng, M.-C.; Niu, X.; Eggerd, J.; Xie, B.; Cheng, J. H. P.; Xu, H.; Zhong, X.-X.; Jiang, H.; Cui, M.; Yan, Y.; Cai, D.
10.1101/2024.10.04.616591 — bioinformatics — Posted on 2024-10-04
4726 Structural basis of Nipah virus replication
Sala, F. A.; Ditter, K.; Dybkov, O.; Urlaub, H.; Hillen, H. S.
10.1101/2024.10.04.616610 — biochemistry — Posted on 2024-10-04
4727 Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome
East, M. P.; Sprung, R. W.; Okumu, D. O.; Olivares-Quintero, J. F.; Joisa, C. U.; Chen, X.; Zhang, Q.; Erdmann-Gilmore, P.; Mi, Y.; Sciaky, N.; Malone, J. P.; Bhatia, S.; McCabe, I. C.; Xu, Y.; Sutcliffe, M. D.; Luo, J.; Spears, P. A.; Perou, C. M.; Earp, H. S.; Carey, L. A.; Yeh, J. J.; Spector, D. L.; Gomez, S. M.; Spanheimer, P. M.; Townsend, R. R.; Johnson, G. L.
10.1101/2024.10.04.614143 — biochemistry — Posted on 2024-10-04
4728 A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs
Buckley, R. M.; Bilgen, N.; Harris, A. C.; Savolainen, P.; Tepeli, C.; Erdogan, M.; Serres Armero, A.; Dreger, D. L.; van Steenbeek, F. G.; Hytönen, M. K.; Hale, J.; Lohi, H.; Cınar Kul, B.; Boyko, A. R.; Ostrander, E. A.
10.1101/2024.10.04.616687 — genomics — Posted on 2024-10-04
4729 k-mer-based GWAS in a wheat collection reveals novel and diverse sources of powdery mildew resistance
Jaegle, B.; Voichek, Y.; Haupt, M.; Sotiropoulos, A. G.; Gauthier, K.; Heuberger, M.; Jung, E.; Herren, G.; Widrig, V.; Leber, R.; Li, Y.; Schierscher, B.; Serex, S.; Boczkowska, M.; Puchta, M.; Bolc, P.; Chalhoub, B.; Stein, N.; Keller, B.; Sanchez-Martin, J.
10.1101/2024.10.03.616421 — genomics — Posted on 2024-10-04
4732 Population history of Swedish cattle breeds: estimates and model checking
Adepoju, D.; Ohlsson, J. I.; Klingström, T.; Rius-Vilarrasa, E.; Johansson, A. M.; Johnsson, M.
10.1101/2024.10.03.616479 — genetics — Posted on 2024-10-04
4734 Quantifying transcriptome turnover on phylogenies bymodeling gene expression as a binary trait
Thompson, A.; May, M. R.; Hopkins, B.; Riedl, N.; Barmina, O.; Liebeskind, B. J.; Zhao, L.; Begun, D.; Kopp, A.
10.1101/2024.10.03.616564 — evolutionary biology — Posted on 2024-10-04
4735 Analyzing Biodiversity in Protected vs. Unprotected Tide Pools
Chen, V.; Campbell, R.; Chirputkar, A.; Tran, E.; Chaturvedi, P.; Han, S.; Lu, A.; Chu, Z.; Erb, M.; Mehta, T.; Bindal, V.; Lee, I.; Benson, A.; Adams, C. T.
10.1101/2024.10.03.616586 — ecology — Posted on 2024-10-04
4736 Germplasm stability in zebrafish requires maternal Tdrd6a and Tdrd6c
Consorte, A.; El Sherif, Y.; Kielisch, F.; Wittkopp, N.; Ketting, R. F.
10.1101/2024.10.04.615777 — developmental biology — Posted on 2024-10-04
4737 ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM
Gonzalez Hernandez, S.; Sato, R.; Sato, Y.; Liu, C.; Li, W.; Liu, C.; Jackson, S.; Kubota, Y.; Mukouyama, Y.-s.
10.1101/2024.10.03.616513 — developmental biology — Posted on 2024-10-04
4738 ATAD2 drives HIRA/histone H3.3-dependent chromatin dynamics
Liakopoulou, A.; Boussouar, F.; Perazza, D.; Barral, S.; Lambert, E.; Wang, T.; Chuffart, F.; Bourova-Flin, E.; Gard, C.; Puthier, D.; Rousseaux, S.; Arnoult, C.; Verdel, A.; Khochbin, S.
10.1101/2024.10.04.616609 — developmental biology — Posted on 2024-10-04
4739 The A-C Linker controls centriole cohesion and duplication
Bournonville, L.; Laporte, M. H.; Borgers, S.; Guichard, P.; Hamel, V.
10.1101/2024.10.04.616628 — cell biology — Posted on 2024-10-04
4740 A post-mitotic in vitro murine as a model of muscle damage and repair
Galluccio, A.; Maurotti, S.; Noto, F. R.; Scionti, F.; Pujia, C.; Mazza, E.; Ferro, Y.; Mare, R.; Geirola, N.; Scopacasa, B.; Candeloro, P.; Tirinato, L.; Sciacqua, A.; Pujia, A.; Romeo, S.; Montalcini, T.
10.1101/2024.10.04.616603 — cell biology — Posted on 2024-10-04
4741 Dissecting autonomous enzyme variability in single cells
Gnann, C.; Cesnik, A.; Sigaeva, A.; Le, T.; Sariyar, S.; Mahdessian, D.; Schutten, R.; Raghavan, P.; Leonetti, M. D.; Lindskog, C.; Uhlen, M.; Axelsson, U.; Lundberg, E.
10.1101/2024.10.03.616530 — cell biology — Posted on 2024-10-04
4744 The C. elegans homolog of Sjögrens Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly
Pfister, J. A.; Agostini, L.; Bournonville, L.; Sankaralingam, P.; Bell, Z. G.; Hamel, V.; Guichard, P.; Biertumpfel, C.; Mizuno, N.; O'Connell, K. F.
10.1101/2024.10.03.616528 — cell biology — Posted on 2024-10-04
4745 Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
Hansen, K. L.; Adachi, A. S.; Braccioli, L.; Kadvani, S.; Boileau, R. M.; Pokorny, B.; Shah, R.; Anderson, E. C.; Martinovic, M.; Zhang, K.; Carel, I.; Bonitto, K.; Blelloch, R.; Fudenberg, G.; de Wit, E.; Nora, E. P.
10.1101/2024.10.04.615095 — molecular biology — Posted on 2024-10-04
4747 D-lactate derived from intestinal bacteria drives lysine D-lactylation to modulate transcription in liver cells
Zang, Y.; Zhang, J.; Xia, M.; Wang, A.; Fan, Z.; Han, Y.; Zhang, H.; Wang, S.; Niu, Z.; Wu, J.; Bai, X.; Tian, S.; Chen, C.; Zhai, G.; Dong, H.; Hu, D.; Cheng, Z.; Zhang, K.
10.1101/2024.10.04.616636 — molecular biology — Posted on 2024-10-04
4749 Universal rules govern plasmid copy number
Ramiro-Martinez, P.; de Quinto, I.; Gama, J. A.; Rodriguez-Beltran, J.
10.1101/2024.10.04.616648 — microbiology — Posted on 2024-10-04
4750 Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein
Radic, L.; Offersgaard, A.; Kadava, T.; Zon, I.; Capella-Pujol, J.; Mulder, F.; Koekkoek, S.; Spek, V.; Chumbe, A.; Bukh, J.; van Gils, M. J.; Sanders, R. W.; Yin, V. C.; Heck, A. J. R.; Gottwein, J. M.; Sliepen, K.; Schinkel, J.
10.1101/2024.10.04.616615 — microbiology — Posted on 2024-10-04
4751 Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate neutrophilic allergic airways disease.
Ravi, V. R.; Korkmaz, F. T.; Lyon De Ana, C.; Lu, L.; Shao, F.-Z.; Odom, C. V.; Barker, K. A.; Ramanujan, A.; Niszczak, E. N.; Goltry, W. N.; Martin, I. M. C.; Ha, C. T.; Quinton, L. J.; Jones, M. R.; Fine, A.; Welch, J. D.; Chen, F.; Belkina, A. C.; Mizgerd, J. P.; Shenoy, A. T.
10.1101/2024.10.03.616494 — immunology — Posted on 2024-10-04
4752 APOE Protects Against Severe Infection with Mycobacterium tuberculosis by Restraining Production of Neutrophil Extracellular Traps
Liu, D.; Jahn, A. N.; Murray, T. A.; Aitchison, J. D.; Gern, B. H.; Urdahl, K. B.; Aderem, A.; Diercks, A. H.; Gold, E. S.
10.1101/2024.10.04.616580 — immunology — Posted on 2024-10-04
4753 Finding Agreement: fMRI-hyperscanning reveals that dyads explore in mental state space to align opinions.
Speer, S. P.; Sened, H.; Mwilambwe-Tshilobo, L.; Falk, E.; Tsoi, L.; Burns, S.; Tamir, D.
10.1101/2024.10.03.616501 — neuroscience — Posted on 2024-10-04
4754 Regulation of REM Sleep Onset and Homeostasis by Preoptic Glutamatergic Neurons
Mondino, A.; Jadidian, A.; Toth, B.; Hambrecht-Wiedbusch, V. S.; Floran-Garduno, L.; Li, D.; York, A. K.; Torterolo, P.; Pal, D.; Burgess, C.; Mashour, G. A.; Vanini, G.
10.1101/2024.10.03.616573 — neuroscience — Posted on 2024-10-04
4755 Spatial and network principles behind neural generation of locomotion
Komi, S.; Winther, A.; Houser, G.; Sorensen, R. J.; Larsen, S.; Bonfils, M.; Li, G.; Berg, R. W.
10.1101/2024.10.03.616472 — neuroscience — Posted on 2024-10-04
4758 Multisensory gamma stimulation enhances adult neurogenesis and improves cognitive function in a mouse model of Down syndrome
Islam, M. R.; Jackson, B.; Schatz, B.; Murdock, M.; Tan, N.; Park, D. S.; Amorim, D. R.; Jiang, F.; Pineda, S. S.; Adaikkan, C.; Fernandez, V.; Geigenmuller, U.; Kellis, M.; Boyden, E. S.; Tsai, L.-H.
10.1101/2024.10.03.616486 — neuroscience — Posted on 2024-10-04
4759 Parallel neuroinflammatory pathways to cerebrovascular injury and amyloid-beta in Alzheimer's disease
Rizvi, B.; Adams, J. N.; Bamford, A.; Kim, S.; Sathishkumar, M.; Tustison, N. J.; Taylor, L.; Tuteja, N.; McMillan, L.; Nan, B.; Cai, H.; Escalante, Y. Y.; Meza, N.; Harris, A. L.; Malhas, R.; Brickman, A. M.; Mapstone, M.; Thomas, E. A.; Yassa, M. A.
10.1101/2024.10.03.616579 — neuroscience — Posted on 2024-10-04
4760 Conflict neurons in cingulate cortex of macaques
Corrigan, B. W.; Errington, S. P.; Sajad, A.; Schall, J. D.
10.1101/2024.10.03.616355 — neuroscience — Posted on 2024-10-04
4762 Contextual Neural Dynamics During Time Perception in Primate Ventral Premotor Cortex
Diaz, H.; Bayones, L.; Alvarez, M.; Andrade, B.; Valero, S.; Zainos, A.; Romo, R.; Rossi-Pool, R.
10.1101/2024.10.03.616577 — neuroscience — Posted on 2024-10-04
4765 Design of bacterial DNT sensors based on computational models
Bahiri Elitzur, S.; Shpigel, E.; Katzir, I.; Alon, U.; Belkin, S.; Tuller, T.
10.1101/2024.10.04.616532 — synthetic biology — Posted on 2024-10-04
4768 H+ drives ultra-fast root-to-root responses to wounding
Ducla, J.; Di Fino, L.; Mentzelopoulou, A.; Talide, L.; Besten, M.; Bernacka-Wojcik, I.; Arbring Sjöström, T.; Zahid, N.; Jämtgard, S.; Stavrinidou, E.; Niittylä, T.; Sprakel, J.; Marhavy, P.
10.1101/2024.10.04.616436 — plant biology — Posted on 2024-10-04
4769 A multi-omics census reveals obesity-associated microRNA miR-let-7 as novel instigator of adipose mitochondrial dysfunction and of intergenerational metabolic decline.
Huang, C.; Park, J.-H.; Altintas, A.; Stanic, N.; Batarlar, H. T.; Malmros, R. V.; Havelund, J.; Faergeman, N. J.; Marcher Larsen, B. D.; Szczepanowska, K.; Lackmann, J.-W.; Trifunovic, A.; Hejbol, E. K.; Detlefsen, S.; Jepsen, I. E.; Kolstrup, S. H.; Laguna Barraza, R. A.; Gonzalez, J.-M.; Khodosevich, K.; Barres, R.; Kornfeld, J.-W.
10.1101/2024.10.03.615866 — physiology — Posted on 2024-10-04
4770 Muscle-specific Keap1 deletion enhances force production but does not prevent inactivity-induced muscle atrophy in mice
Miranda, E. R.; Shahtout, J. L.; Watanabe, S.; Milam, N.; Karasawa, T.; Rout, S.; Atkinson, D. L.; Holland, W. L.; Drummond, M. J.; Funai, K.
10.1101/2024.10.03.616570 — physiology — Posted on 2024-10-04
4772 Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy
Logun, M.; Wang, X.; Sun, Y. Y.; Bagley, S.; Li, N.; Desai, A.; Zhang, D. Y.; Nasrallah, M.; Pai, E. L.-L.; Oner, B. S.; Plesa, G.; Siegel, D.; Binder, Z. A.; Ming, G.-L.; Song, H.; O'Rourke, D.
10.1101/2024.10.03.616503 — cancer biology — Posted on 2024-10-04
4773 RUVBL1 and RUVBL2 are druggable MYCN regulators in neuroblastoma.
Siaw, J. T.; Claeys, A.; Lai, W.-Y.; Borenas, M.; Hilgert, E.; Bekaert, S.-L.; Sanders, E.; Kaya, I.; Van Dorpe, J.; Speleman, F.; Durinck, K.; Hallberg, B.; Palmer, R.; Van den Eynden, J.
10.1101/2024.10.03.616410 — cancer biology — Posted on 2024-10-04
4774 Single-cell RNA sequencing on formalin-fixed and paraffin-embedded (FFPE) tissue identified multi-ciliary cells in breast cancer
Gonzalez-Martinez, S.; Carretero-Barrio, I.; Perez-Mies, B.; Fernandez-Lanza, V.; Garcia-Cosio, M.; Caniego-casas, T.; Hardisson, D.; Estaban-Rodriguez, I.; Cortes, J.; Palacios, J.
10.1101/2024.10.04.616471 — cancer biology — Posted on 2024-10-04
4777 Mosaic Regulation of Stress Pathways Underlies Senescent Cell Heterogeneity
Avelar, R. A.; Duffield, T.; Lagger, C.; Krstevska, N.; Breuer, M.; de Magalhaes, J. P.
10.1101/2024.10.03.616489 — bioinformatics — Posted on 2024-10-04
4778 More cells, more doublets in highly multiplexed single-cell data
Howitt, G.; Dixit, G.; Aharon, R.; Streeton-Cook, V.; Ling, L.; Hickey, P. F.; Amann-Zalcenstein, D.; Gubbels, L.; Shanthikumar, S.; Ranganathan, S.; Neeland, M.; Maksimovic, J.; Oshlack, A.
10.1101/2024.10.03.616596 — bioinformatics — Posted on 2024-10-04
4779 Computational design of developable therapeutic antibodies: efficient traversal of binder landscapes and rescue of escape mutations
Dreyer, F. A.; Schneider, C.; Kovaltsuk, A.; Cutting, D.; Byrne, M. J.; Nissley, D. A.; Wahome, N.; Kenlay, H.; Marks, C.; Errington, D.; Gildea, R. J.; Damerell, D.; Tizei, P.; Bunjobpol, W.; Darby, J. F.; Drulyte, I.; Hurdiss, D. L.; Surade, S.; Pires, D. E. V.; Deane, C. M.
10.1101/2024.10.03.616038 — bioinformatics — Posted on 2024-10-04
4786 Reducing spatial heterogeneity in coverage improves the effectiveness of dog vaccination against rabies
Ferguson, E.; Lugelo, A.; Czupryna, A.; Anderson, D.; Lankester, F.; Sikana, L.; Dushoff, J.; Hampson, K.
10.1101/2024.10.03.616420 — ecology — Posted on 2024-10-04
4789 Disruption of riboflavin biosynthesis in mycobacteria establishes 5-amino-6-D-ribitylaminouracil (5-A-RU) as key precursor of MAIT cell agonists
Chengalroyen, M. D.; Oketade, N.; Worley, A.; Lucas, M.; Ramirez, L. N.; Raphela, M. L.; Swarbrick, G.; Warner, D. F.; Lewinsohn, D.; Mehaffy, C.; Adams, E. J.; Hildebrand, W.; Dobos, K. M.; Mizrahi, V.; Lewinsohn, D.
10.1101/2024.10.03.616430 — immunology — Posted on 2024-10-04
4790 Conserved chromatin regulators control the transcriptional immune response to intracellular pathogens in Caenorhabditis elegans
Tecle, E.; Li, S.; Blanchard, M. J.; Bui, T.; Chhan, C. B.; Underwood, R. S.; Bakowski, M. A.; Troemel, E. R.; Lazetic, V.
10.1101/2024.10.03.616425 — immunology — Posted on 2024-10-04
4791 Glycogen synthase kinase-3 is essential for Treg development and function
Kandasamy, M.; Andrew, H. F.; Mitchell, R.; Raza, I. G.; Borsa, M.; Attar, M.; Clarke, A.
10.1101/2024.10.03.616474 — immunology — Posted on 2024-10-04
4795 Secreted spermidine synthase reveals a paracrine role for PGC1a-induced growth suppression in prostate cancer
Schaub Clarigue, A.; Hermanova, I.; Pintor Rial, A.; Macchia, A.; Valcarcel Jimenez, L.; Lectez, B.; Garcia-Longarte, S.; Fagoaga-Eugui, M.; Zabala-Letona, A.; Pujana-Vaquerizo, M.; Royo, F.; Azkargorta, M.; Berra, E.; Sutherland, J. D.; Peinado, H.; Falcon-Perez, J. M.; Elortza, F.; Carracedo, A.; Torrano, V.
10.1101/2024.10.04.614869 — cancer biology — Posted on 2024-10-04
4796 Narratives for positive nature futures in Europe
D'Alessio, A.; Fornarini, C.; Fernandez, N.; Namasivayam, A. S.; Visconti, P.; Dertien, J.; Hallfors, M.; Jung, M.; Moreira, F.; O'Connor, L.; Osti, M.; Quintero-Uribe, L. C.; Marei Viti, M.; Pereira, H.; Verburg, P. H.; Rondinini, C.
10.1101/2024.10.04.616255 — ecology — Posted on 2024-10-04
4798 Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics
Baek, K.; Metivier, R. J.; Roy Burman, S. S.; Bushman, J. W.; Yoon, H.; Lumpkin, R. J.; Abeja, D. M.; Lakshminarayan, M.; Yue, H.; Ojeda, S.; Verano, A. L.; Gray, N. S.; Donovan, K. A.; Fischer, E. S.
10.1101/2024.09.11.612438 — cancer biology — Posted on 2024-10-04
4799 Confinement by liquid-liquid interface replicates in vivo neutrophil deformations and elicits bleb based migration
Schrope, J. H.; Horn, A.; Lazorchak, K.; Tinnen, C. W.; Stevens, J. J.; Farooqui, M.; Li, J.; Bennin, D.; Robertson, T.; Juang, T. D.; Ahmed, A.; Li, C.; Huttenlocher, A.; Beebe, D.
10.1101/2023.06.14.544898 — bioengineering — Posted on 2024-10-04
4800 An effective model for community-based conservation around authorized fishing settlements inside a devolved Wildlife Management Area in southern Tanzania
Duggan, L. M.; Tarimo, L. J.; Walsh, K. A.; Kavishe, D. R.; Crego, R. D.; Elisa, M.; Mombo, F.; Butler, F.; Killeen, G.
10.1101/2024.07.30.605829 — ecology — Posted on 2024-10-04
4801 Dynamic changes in mitochondria support phenotypic flexibility of microglia
Espinoza, K.; Schaler, A. W.; Gray, D. T.; Sass, A.; Moore, K.; Yu, M.; Chamorro, C.; De Biase, L. M.
10.1101/2024.05.18.594002 — neuroscience — Posted on 2024-10-04
4804 PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
Wang, J.; Shi, Y.; Wang, Y.; Shen, Y.; Liu, H.; Sun, S.; Wang, Y.; Zhou, X.; Zhou, Y.; Zeng, X.; Li, J.; Chen, Q.
10.1101/2024.07.23.604769 — cancer biology — Posted on 2024-10-04
4805 A Targeted Reference Database for Improved Analysis of Environmental 16S rRNA Oxford Nanopore Sequencing Data
Philip, M.; Nilsen, T.; Majaneva, S.; Pettersen, R.; Stokkan, M.; Ray, J. L.; Keeley, N.; Rudi, K.; Snipen, L.-G.
10.1101/2024.10.03.616456 — bioinformatics — Posted on 2024-10-04
4807 multimedia: Multimodal Mediation Analysis of Microbiome Data
Jiang, H.; Miao, X.; Thairu, M. W.; Beebe, M.; Grupe, D. W.; Davidson, R. J.; Handelsman, J.; Sankaran, K.
10.1101/2024.03.27.587024 — bioinformatics — Posted on 2024-10-04
4808 Electromagnetic Stimulated Anisotropic Hydrogels for Guided Neuronal Morphogenesis
Jensen, B. N.; Tong, T.; Skovborg, G.; Zhang, Y.; Mueller, C.; Matthiesen, C. L.; Eschen, J. T.; Elbaek, K. J.; Wang, Y.; Pallesen, L. T.; Seliktar, D.; Dong, M.; Vaegter, C. B.; Korshoej, A. R.; Chen, M.
10.1101/2024.09.29.615659 — bioengineering — Posted on 2024-10-04
4809 Identification of Long Non-coding RNA Candidate Disease Genes Associated with Clinically Reported CNVs in Congenital Heart Disease
Penaloza, J. S.; Moreland, B.; Gaither, J. B.; Landis, B. J.; Ware, S. M.; McBride, K. L.; White, P.; CCVM Consortium,
10.1101/2024.09.30.615967 — genomics — Posted on 2024-10-04
4820 Large-scale cortical networks are organized in structured cycles
van Es, M. W. J.; Higgins, C.; Gohil, C.; Quinn, A. J.; Vidaurre, D.; Woolrich, M. W.
10.1101/2023.07.25.550338 — neuroscience — Posted on 2024-10-04
4823 Lateral Entorhinal Cortex Dysfunction in Alzheimer's Disease Mice
Raghuraman, R.; Aoun, A.; Herman, M.; Shetler, C. O.; Nahmani, E.; Hussaini, S. A.
10.1101/2024.04.15.589589 — neuroscience — Posted on 2024-10-04
4828 Co-cultivation with Azolla affects the metabolome of whole rice plant beyond canonical inorganic nitrogen fertilization
Consorti, E.; Costarelli, A.; Cannavo, S.; Cerri, M.; Valeri, M. C.; Reale, L.; Saccomanno, A.; Paleni, C.; Gregis, V.; Kater, M. M.; Brilli, F.; Paolocci, F.; Ghirardo, A.
10.1101/2024.10.02.615589 — plant biology — Posted on 2024-10-04
4829 Characterization of the cellular components of mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells regulating lymphatic contractions
Zawieja, S. D.; Pea, G. A.; Broyhill, S. E.; Patro, A.; Bromert, K. H.; Norton, C. E.; Kim, H. J.; Sivasankaran, S. K.; Li, M.; Castorena-Gonzalez, J. A.; Drumm, B. T.; Davis, M. J.
10.1101/2023.08.24.554619 — physiology — Posted on 2024-10-04
4831 Placental Malaria Induces a Unique Methylation Profile Associated with Fetal Growth Restriction
Ozarslan, N.; Mong, C.; Ategeka, J.; Li, L.; Buarpung, S.; Robinson, J. F.; Kizza, J.; Kakuru, A.; Kamya, M. R.; Dorsey, G.; Rosenthal, P. J.; Gaw, S. L.
10.1101/2024.05.09.593431 — genetics — Posted on 2024-10-04
4832 Sex-, development-, and nutrition-dependent expression of a major age-at-maturity gene in Atlantic salmon
Asheim, E. R.; Debes, P.; House, A.; Liljestrom, P.; Ruokolainen, A.; Frapin, M.; Donner, I.; Ahi, E. P.; Erkinaro, J.; Verta, J.-P.; Primmer, C. R.
10.1101/2024.09.15.613130 — genetics — Posted on 2024-10-04
4836 3D Reconstruction Enables High-Throughput Phenotyping and Quantitative Genetic Analysis of Phyllotaxy
Davis, J. M.; Gaillard, M.; Tross, M. C.; Shrestha, N.; Ostermann, I.; Grove, R. J.; Li, B.; Benes, B.; Schnable, J. C.
10.1101/2024.10.03.616344 — plant biology — Posted on 2024-10-04
4838 An effective method of measuring nanobody binding kinetics and competition-based epitope mapping using biolayer interferometry
Bates, T. A.; Gurmessa, S. K.; Reyes-Weinstein, J. B.; Trank-Greene, M.; Wrynla, X. H.; Anastas, A.; Anley, T. W.; Hinchliff, A.; Shinde, U.; Burke, J. E.; Tafesse, F. G.
10.1101/2024.10.03.616354 — biochemistry — Posted on 2024-10-04
4839 Effects of Oral Exposure to HPAI H5N1 Pasteurized in Milk on Immune Response and Mortality in Mice
Brigleb, P. H.; Roubidoux, E. K.; Livingston, B.; Sharp, B.; Meliopoulos, V. A.; Tan, S.; Morris, D. R.; Lazure, L.; Schultz-Cherry, S.
10.1101/2024.10.03.616493 — microbiology — Posted on 2024-10-04
4844 ADAMTS7 Promotes Smooth Muscle Foam Cell Expansion in Atherosclerosis
Chung, A.; Chang, H. K.; Pan, H.; Bashore, A. C.; Shuck, K.; Matias, C. V.; Gomez, J.; Yan, H.; Li, M.; Bauer, R. C.
10.1101/2024.02.26.582156 — pathology — Posted on 2024-10-04
4845 Insulin and Exercise-induced Phosphoproteomics of Human Skeletal Muscle Identify REPS1 as a New Regulator of Muscle Glucose Uptake
Kjaergaard, J.; Lindqvist, C. B.; Jessen, S.; Garcia-Urena, M.; Ehrlich, A.; Schlabs, F.; Quesada, J. P.; Schmalbruch, J.; Small, L.; Thomassen, M.; Lemminger, A. K.; Eibye, K.; Gonzalez-Franquesa, A.; Stidsen, J. v.; hoejlund, k.; Kilpelainen, T.; Bangsbo, J.; Treebak, J. T.; Hostrup, M.; Deshmukh, A. S.
10.1101/2023.11.10.566644 — biochemistry — Posted on 2024-10-04
4847 Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency
Naqvi, A. S.; Corbett, R. J.; Seghal, P.; Conkrite, K. L.; Rathi, K. S.; Ennis, B. M.; Hayer, K. E.; Zhang, B.; Brown, M. A.; Miller, D. P.; Kraya, A.; Dybas, J. M.; Geng, Z.; Blackden, C.; Arif, S.; Chroni, A.; Lahiri, A.; Hollawell, M. L.; Storm, P. B.; Foster, J. B.; Koptyra, M.; Madsen, P. J.; Diskin, S. J.; Thomas-Tikhonenko, A.; Resnick, A. C.; Rokita, J. L.
10.1101/2024.08.03.606419 — genomics — Posted on 2024-10-04
4848 A spatially-resolved blueprint of the developing human lung reveals a basal cell population regulated by a WNT-driven niche
Hsu, P. P.; Conchola, A. S.; Frum, T.; Dong, X.; Tudrick, L.; Ponnusamy, V.; Downey, M. S.; Wu, M.; Yang, M.; Lee, Y.; Niestroy, E.; Tsai, Y.-H.; Wu, A.; Huang, S.; Glass, I. A.; Merajver, S. D.; Spence, J. R.
10.1101/2024.10.01.612096 — developmental biology — Posted on 2024-10-04
4849 SAM-dependent viral MTase inhibitors: herbacetin and caffeic acid phenethyl ester, structural insights into dengue MTase
Bhutkar, M.; Kumar, A.; Rani, R.; Singh, V.; Pathak, A.; Kothiala, A.; Mahajan, S.; Waghmode, B.; Kumar, R.; Mudgal, R.; Sircar, D.; Kumar, P.; Tomar, S.
10.1101/2022.05.31.494145 — microbiology — Posted on 2024-10-04
4851 Role of Hepatocyte RIPK1 in Maintaining Liver Homeostasis during Metabolic Challenges
Zhang, W.; Liu, H.; Zhang, D.; Yi, Y.; Tao, L.; Huang, S.; Zhao, X.; Shao, Q.; Li, P.; Zhang, J.; Pan, Y.; Lu, W.; Zhang, H.; Chen, Y.; Weng, D.
10.1101/2024.03.04.583302 — immunology — Posted on 2024-10-04
4852 Attenuated processing of vowels in the left hemisphere predicts speech-in-noise perception deficit in children with autism
Fadeev, K. A.; Romero Reyes, I. V.; Goiaeva, D. E.; Obukhova, T. S.; Ovsiannikova, T. M.; Prokofyev, A. O.; Rytikova, A. M.; Novikov, A. Y.; Kozunov, V. V.; Stroganova, T. A.; Orekhova, E. V.
10.1101/2024.06.24.600191 — neuroscience — Posted on 2024-10-04
4853 Unveiling Multi-level and Multi-modal Semantic Representations in the Human Brain using Large Language Models
Nakagi, Y.; Matsuyama, T.; Koide-Majima, N.; Yamaguchi, H. Q.; Kubo, R.; Nishimoto, S.; Takagi, Y.
10.1101/2024.02.06.579077 — neuroscience — Posted on 2024-10-04
4856 Spatio-temporal transformers for decoding neural movement control
Candelori, B.; Bardella, G.; Spinelli, I.; Ramawat, S.; Pani, P.; Ferraina, S.; Scardapane, S.
10.1101/2024.04.15.589534 — animal behavior and cognition — Posted on 2024-10-04
4857 CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells
Meng, X.; Zhu, Y.; Liu, K.; Wang, Y.; Liu, X.; Liu, C.; Zeng, Y.; Wang, S.; Gao, X.; Shen, X.; Chen, J.; Tao, S.; Xu, Q.; Dong, L.; Shen, L.; Wang, L.
10.1101/2024.09.30.615805 — immunology — Posted on 2024-10-04
4858 Meta2DB: Curated Shotgun Metagenomic Feature Sets and Metadata for Health State Prediction
Kok, C. R.; Mulakken, N.; Thissen, J. B.; Manuel Marti, J.; Lee, R.; Trainer, J. B.; Goncalves, A.; Ranganathan, H.; Avila-Herrera, A.; Jaing, C.; Be, N. A.
10.1101/2024.10.03.616398 — microbiology — Posted on 2024-10-04
4865 Semantic Dimensions Support the Cortical Representation of Object Memorability
Slayton, M. A.; Howard, C. M.; Huang, S.; Hovhannisyan, M.; Cabeza, R.; Davis, S. W.
10.1101/2024.10.03.616545 — neuroscience — Posted on 2024-10-03
4866 Guided Visual Search is associated with a feature-based priority map in early visual cortex
Duecker, K.; Shapiro, K. L.; Hanslmayr, S.; Griffiths, B. J.; Pan, Y.; Wolfe, J.; Jensen, O.
10.1101/2024.10.03.616568 — neuroscience — Posted on 2024-10-03
4869 Potent photoswitch for expression of biotherapeutics in mammalian cells by light
Gebel, J.; Ciglieri, E.; Stahl, R.; Duthie, F.; Moeglich, A.; Mueller-Hartmann, H.; Schmidt, H.-M.; Wachten, D.
10.1101/2024.10.03.616529 — molecular biology — Posted on 2024-10-03
4871 Microbiome stability is linked to coral thermotolerance
Baquiran, J. I. P.; Quijano, J. B.; van Oppen, M. J. H.; Cabaitan, P. C.; Harrison, P. L.; Conaco, C.
10.1101/2024.10.03.616497 — microbiology — Posted on 2024-10-03
4875 High-Throughput Optimization of Paper-Based Cell-Free Biosensors
Garcia, D. C.; Davies, J. P.; Davidson, C. E.; Phillips, D. A.; Miklos, A. E.; Lux, M. M.
10.1101/2024.10.03.616554 — synthetic biology — Posted on 2024-10-03
4877 LIET Model: Capturing the kinetics of RNA polymerase from loading to termination
Stanley, J. T.; Barone, G. E. F.; Townsend, H. A.; Sigauke, R. F.; Allen, M. A.; Dowell, R. D.
10.1101/2024.10.03.616401 — bioinformatics — Posted on 2024-10-03
4883 Accurate genotyping of three major respiratory bacterial pathogens with ONT R10.4.1 long-read sequencing
Zidane, N.; Rodrigues, C.; Bouchez, V.; Rethoret-Pasty, M.; Passet, V.; Brisse, S.; Crestani, C.
10.1101/2024.10.03.616467 — genomics — Posted on 2024-10-03
4885 Pathological PNPase variants with altered RNA binding and degradation activity affect the phenotype of bacterial and human cell models
Pizzoccheri, R.; Falchi, F. A.; Alloni, A.; Caldarulo, M.; Camboni, T.; Zambelli, F.; Pavesi, G.; Visentin, C.; Camilloni, C.; Sertic, S.; Briani, F.
10.1101/2024.10.03.616462 — genetics — Posted on 2024-10-03
4886 DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome
Tateossian, H.; Southern, A.; Vikhe, P.; Lana-Elola, E.; Watson-Scales, S.; Gibbins, D.; Williams, D.; Purnell, T.; Mburu, P.; Parker, A.; Norris, D. P.; Santos-Cortez, R. L. P.; Herrmann, B. W.; Wells, S.; Lad, H. V.; Fisher, E.; Tybulewicz, V. L.; Brown, S. D. M.
10.1101/2024.10.03.616443 — genetics — Posted on 2024-10-03
4888 Lipid Droplet Targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis
Teskey, G.; Tiwari, N.; Butcko, A. J.; Kumar, A.; Yadav, A.; Huang, Y.-m. M.; Kelly, C. V.; Granneman, J. G. G.; Perfield, J. W.; Mottillo, E. P.
10.1101/2024.10.03.616525 — cell biology — Posted on 2024-10-03
4889 TECPR2 is a Rab5 effector that regulates endosomal cargo recycling
Paul, S.; Pant, R.; Sharma, P.; Walia, K.; Gupta, S.; Aseem, A.; Bajwa, K. K.; George, R.; Varma, Y.; Bhatia, T.; Ramachandran, R.; Tuli, A.; Sharma, M.
10.1101/2024.10.03.616509 — cell biology — Posted on 2024-10-03
4891 Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures
Milenkovic, I.; Cruciani, S.; Llovera, L.; Lucas, M. C.; Medina, R.; Pauli, C.; Heid, D.; Muley, T.; Schneider, M. A.; Klotz, L.; Allgaeuer, M.; Lattuca, R.; Lafontaine, D. L.; Mueller-Tidow, C.; Novoa, E. M.
10.1101/2024.10.03.616461 — molecular biology — Posted on 2024-10-03
4892 Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East Respiratory Syndrome coronavirus disease severity
Sheahan, T. P.; Sims, A. C.; Schaefer, A.; Okuda, K.; Leist, S. R.; Cockrell, A. S.; Jensen, K. L.; Kyle, J.; Burnum-Johnson, K. E.; Stratton, K. G.; Lamar, N. C.; Nicora, C. D.; Weitz, K. K.; Smith, R.; Metz, T.; Waters, K. M.; Boucher, R.; Montgomery, S. A.; Baric, R. S.; Kocher, J.
10.1101/2024.10.03.616483 — microbiology — Posted on 2024-10-03
4894 Limiting hearing loss in transgenic mouse models
Babola, T. A.; Donovan, N.; Darcy, S. S.; Spjut, C. D.; Kanold, P. O.
10.1101/2024.10.03.616327 — neuroscience — Posted on 2024-10-03
4896 Estimating the seroprevalence of tuberculosis (Mycobacterium bovis) infection in a wild deer population in southwest England
Jinks, R.; Hollingdale, A.; Avigad, R.; Velarde, J.; Pugsley, C.; de la Rua-Domenech, R.; Pritchard, C.; Roberts, T.; Clark, J.; Robinson, N.; Maynes, R.; Withenshaw, S.; Smith, G.
10.1101/2024.10.03.613747 — zoology — Posted on 2024-10-03
4899 HLAIIPred: Cross-Attention Mechanism for Modeling the Interaction of HLA Class II Molecules with Peptides
Haghighatlari, M.; Marze, N.; Seward, R. J.; Ciarla, A.; Dhule, S.; Hindin, R.; Calderini, J.; Keenan, B.; Hall-Swan, S.; Hickling, T. P.; Bennett, E.; Rai, B.; Tourdot, S.
10.1101/2024.10.01.616078 — bioinformatics — Posted on 2024-10-03
4900 PoreMeth2: decoding the evolution of methylome alterations with Nanopore sequencing
Mattei, G.; Baragli, M.; Gega, B.; Mingrino, A.; Chieca, M.; Ducci, T.; Frige', G.; Mazzarella, L.; D'Aurizio, R.; De Logu, F.; Nassini, R.; Pelicci, P. G.; Magi, A.
10.1101/2024.10.03.616449 — bioinformatics — Posted on 2024-10-03
4901 Bottlebrush polymers with sequence-controlled backbones for enhanced oligonucleotide delivery
Wei, Y.; Chen, P.; Li, D.; Lin, J.; Sun, T.; Wang, Y.; Yang, S.; Nenopoulos, C.; Oetheimer, C.; Li, Y.; Xue, C.; Mona, M.; Zhang, K.
10.1101/2024.10.03.616318 — bioengineering — Posted on 2024-10-03
4902 Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach
Pearson, L.-A.; Petit, A.-P.; Mendoza-Martinez, C.; Bellany, F.; Lin, D.; Niven, S.; Swift, R.; Eadsforth, T.; Fyfe, P. K.; Paul, M.; Postis, V.; Hu, X.; Cowling, V.; Gray, D. W.
10.1101/2024.10.03.614057 — biochemistry — Posted on 2024-10-03
4903 Molecular basis of autoimmune disease protection by MDA5 variants
Singh, R.; Herrero del Valle, A.; Joiner, J. D.; Zwaagstra, M.; Ferguson, B. J.; van Kuppeveld, F. J. M.; Modis, Y.
10.1101/2024.10.03.616466 — biochemistry — Posted on 2024-10-03
4905 STAMP: Single-Cell Transcriptomics Analysis and Multimodal Profiling through Imaging
Pitino, E.; Pascual-Reguant, A.; Segato-Dezem, F.; Wise, K.; Salvador-Martinez, I.; Crowell, H. L.; Courtois, E.; Flynn, W. F.; Sivajothi, S.; Soja, E.; Ruiz, S.; Caratu, G.; Sullivan, A.; Mora-Roldan, G. A.; Dredge, K.; Marao, M.; Liu, Y.; Chasteen, H.; Mohenska, M.; Polo, J.; Nieto, J. C.; Plummer, J. T.; Heyn, H.; Martelotto, L. G.
10.1101/2024.10.03.616013 — genomics — Posted on 2024-10-03
4906 Sex and genetic background influence intravenous oxycodone self-administration in the Hybrid Rat Diversity Panel
Duffy, E. P.; Ward, J. O.; Hale, L. H.; Brown, K. T.; Kwilasz, A. J.; Mehrhoff, E. A.; Saba, L. M.; Ehringer, M. A.; Bachtell, R. K.
10.1101/2024.10.03.615948 — genetics — Posted on 2024-10-03
4909 Ancestral complexity and constrained diversification of the ant olfactory system
Marty, S.; Couto, A.; Brard, N.; Dawson, E. H.; d'Ettorre, P.; Montgomery, S. H.; Sandoz, J.-C.
10.1101/2024.10.03.616251 — evolutionary biology — Posted on 2024-10-03
4910 Gene-by-environment interactions and adaptive body size variation in mice from the Americas
Mack, K. L.; Landino, N. P.; Tertyshnaia, M.; Longo, T. C.; Vera, S. A.; Crew, L. A.; McDonald, K.; Phifer-Rixey, M.
10.1101/2024.10.03.616282 — evolutionary biology — Posted on 2024-10-03
4911 The genetic diversity of the soybean rust pathogen Phakopsora pachyrhizi has been driven by two major evolutionary lineages
Rocha, V. D. d.; Ferreira, E. G. C.; Castanho, F. M.; Kuwahara, M. K.; Godoy, C. V.; Meyer, M. C.; Pedley, K. F.; Voegele, R. T.; Lipzen, A.; Barry, K.; Grigoriev, I. V.; Loehrer, M.; Schaffrath, U.; Sirven, C.; Duplessis, S.; Marcelino, F.
10.1101/2024.10.03.616435 — evolutionary biology — Posted on 2024-10-03
4913 An evolutionarily conserved role for VEGF signaling in the expansion of non-vascular tissue during regeneration.
Savage, A. M.; Wagner, A. C.; Kim, R. T.; Gilbert, P.; Singer, H. D.; Chen, E.; Kim, E. M.; Lopez, N.; Dooling, K. E.; Paoli, J. C.; Wu, S. Y. C.; Bohm, S.; Chilambi, R.; Froitzheim, T.; Blair, S. J.; Powell, C. J.; Abouelela, A.; Luong, A. G.; Thornton, K. N.; Tajer, B.; Payzin-Dogru, D.; Whited, J. L.
10.1101/2024.10.01.616057 — developmental biology — Posted on 2024-10-03
4915 Fatty acid desaturation guides cellular decisions between ferroptosis and cellular senescence
Kuehnemann, C.; Jezak, S. T.; Mogck, B. A.; Kura, N.; Che, Y.; Vaittinen, M.; Siokas, I.; Tariq, R.; Deshpande, S.; Guthrie, C. M.; Tan, X.; Aimontche, E.; Zheng, T.; Greenberg, A. S.; Wang, X.-D.; Kitazawa, K.; Dolnikowski, G.; Cheng, Y.; Matthan, N. R.; Ramanathan, A.; Pihlajamaki, J.; Korstanje, R.; Wiley, C. D.
10.1101/2024.10.03.616257 — cell biology — Posted on 2024-10-03
4916 A bifunctional snoRNA with separable activities in guiding rRNA 2'-O-methylation and scaffolding gametogenesis effectors
Leroy, E.; Challal, D.; Pelletier, S.; Goncalves, C.; Menant, A.; Marchand, V.; Jaszczyszyn, Y.; van Dijk, E.; Naquin, D.; Andreani, J.; Motorin, Y.; PALANCADE, B.; Rougemaille, M.
10.1101/2024.10.03.615557 — molecular biology — Posted on 2024-10-03
4917 Delayed viral clearance and altered inflammatory responses resulted in increased severity of SARS-CoV-2 infection in aged mice.
Lacasse, E.; Dubuc, I.; Gudimard, L.; Dos Santos Pereira Andrade, A. C.; Gravel, A.; Greffard, K.; Chamberland, A.; Oger, C.; Galano, J.-M.; Durand, T.; Philipe, E.; Blanchet, M.-R.; Bilodeau, J.-F.; Flamand, L.
10.1101/2024.10.03.616431 — microbiology — Posted on 2024-10-03
4919 Microgravity and low muon radiation affect viral pathogenesis and physiology in Caenorhabditis elegans
Villena-Gimenez, A.; Castiglioni, V. G.; Legarda, E. G.; Munoz-Sanchez, J. C.; Gonzalez, R.; Elena, S. F.
10.1101/2024.10.03.616447 — microbiology — Posted on 2024-10-03
4920 Novel murine model of human astrovirus infection reveals a cardiovascular tropism
Owen, M. C.; Zhou, Y.; Dudley, H.; Feehley, T.; Hahn, A.; Yokoyama, C. C.; Axelrod, M. L.; Lin, C.-Y.; Wang, D.; Janowski, A. B.
10.1101/2024.10.03.616429 — microbiology — Posted on 2024-10-03
4921 Genomic Analysis of Salmonella enterica from cattle, beef and humans in the Greater Tamale Metropolis of Ghana
Sunmonu, G. T.; Saba, C. K. S.; Odih, E. E.; Bright, O.; Osei, E. E. Y.; Mensah, A.; Abdallah, S.; Alhassan, A.-R.; Kpordze, S. W.; Akinlabi, O. C.; Oaikhena, A. O.; Egyir, B.; Okeke, I. N.
10.1101/2024.10.03.616133 — microbiology — Posted on 2024-10-03
4924 A triple serine motif in the intracellular domains of sortilin-related receptors SorCS1-3 regulates neurotrophic activity
Dalby, A.; Ollendorff, M. K.; Byg, L. M.; Christiansen, S. B.; Boeggild, S.; Qvist, P.; Nyengaard, J. R.; Madsen, P.; Molgaard, S.; Glerup, S.
10.1101/2024.10.03.616089 — neuroscience — Posted on 2024-10-03
4925 Exploring the trade-off between deep-learning and explainable models for brain-machine interfaces
Cubillos, L. H.; Revach, G.; Mender, M. J.; Costello, J. T.; Temmar, H.; Hite, A.; Zutshi, D.; Wallace, D. M.; Ni, X.; Kelberman, M. M.; Willsey, M. S.; van Sloun, R. J. G.; Shlezinger, N.; Patil, P.; Draelos, A.; Chestek, C. A.
10.1101/2024.10.03.616126 — neuroscience — Posted on 2024-10-03
4926 HBN-EEG: The FAIR implementation of the Healthy Brain Network (HBN) electroencephalography dataset
Shirazi, S. Y.; Franco, A.; Scopel Hoffmann, M.; Esper, N.; Truong, D.; Delorme, A.; Milham, M.; Makeig, S.
10.1101/2024.10.03.615261 — neuroscience — Posted on 2024-10-03
4927 Deep-learning and analytical models give distinct results for the brain structure-function relationship in health and in psychosis
Cai, Q.; Thomas, H.; Hyde, V.; Luque Laguna, P.; McNabb, C. B.; Singh, K. D.; Jones, D. K.; Messaritaki, E.
10.1101/2024.10.03.616264 — neuroscience — Posted on 2024-10-03
4928 Unveiling the role of miRNAs from MSC-EVs in neuroinflammation and behavioral impairments induced by chronic alcohol consumption
Mellado, S.; Touahri, N.; Montagud-Romero, S.; Perpina-Clerigues, C.; Garcia-Garcia, F.; Moreno-Manzano, V.; Guerri, C.; Rodriguez-Arias, M.; Pascual, M.
10.1101/2024.10.03.616225 — neuroscience — Posted on 2024-10-03
4929 Dietary lipid is largely deposited in skin and rapidly affects insulating properties
Riley, N.; Kasza, I.; Hermsmeyer, I. D.; Trautman, M.; Barrett-Wilt, G.; Jain, R.; Simcox, J. A.; Yen, C.-L. E.; MacDougald, O. A.; Lamming, D. W.; Alexander, C. M.
10.1101/2024.10.03.615679 — physiology — Posted on 2024-10-03
4930 Detection of titanium nanoparticles in human, animal and infant formula milk
Rivard, C.; Djebrani Oussedik, N.; Cloix, R.; Hue Beauvais, C.; Kuszla, N.; Ivanova, E.; Simon, M.; Dufour, A.; Launay, F.; Gazeau, F.; Acloque, H.; Parat, S.; Poupon, J.; Burtey, A.
10.1101/2024.10.03.616116 — physiology — Posted on 2024-10-03
4931 Haematobiochemical Alterations and Lesion Characterization Induced by Haemonchosis in Sheep Slaughtered at Gondar ELFORA Abattoir, North West Ethiopia
Malede, B. A.; Kebede, M. C.; Berihun, A. M.; Mekonnen, M. Y.; Yesuf, M.; Mitiku, T.; Birhan, M.; Kenubih, A. W.; Temesgen, A. B.
10.1101/2024.10.03.616054 — pathology — Posted on 2024-10-03
4932 Simulated Solute Tempering 2
Stratmann, D.; Moroy, G.; Tuffery, P.; Murail, S.
10.1101/2024.10.03.613476 — biophysics — Posted on 2024-10-03
4934 A Targeted Reference Database for Improved Analysis of Environmental 16S rRNA Oxford Nanopore Sequencing Data
Philip, M.; Nilsen, T.; Majaneva, S.; Pettersen, R.; Stokkan, M.; Ray, J. L.; Keeley, N.; rudi, k.; Snipen, L.-G.
10.1101/2024.10.03.616456 — bioinformatics — Posted on 2024-10-03
4935 Upper bill bending as an adaptation for nectar feeding in hummingbirds
Rico-Guevara, A.; Sustaita, D.; Hurme, K.; Hannah, J. E.; Jung, S.; Field, D. J.
10.1101/2024.10.01.615288 — evolutionary biology — Posted on 2024-10-03
4936 CellStudio: a Modular, Tunable and Accessible Platform for Analysis of Growth Factors Secretions in Cell Cultures
Azuaje-Hualde, E.; Lartitegui-Meneses, N.; Alonso-Cabrera, J.; Inchaurraga-Llamas, A.; Alvarez-Brana, Y.; Martinez de Pancorbo, M.; Benito-Lopez, F.; Basabe-Desmonts, L.
10.1101/2024.10.03.614356 — cell biology — Posted on 2024-10-03
4939 EDTA tubes are suitable for insulin and C-peptide measurement in resource-limited settings and can be stored at room temperature for up to 24 hours
Nathan, M.; Mukasa, R.; Sekitoleko, I.; Balungi, P. A.; Kakumba, R. M.; Ongaria, T.; Nkabura, H.; Nyirenda, M.; Niwaha, A. J.; Nakanga, W. p.
10.1101/2024.10.01.616204 — biochemistry — Posted on 2024-10-03
4940 Gut Microbial Impact on Colitis and Colitis-Associated Carcinogenesis in a Primary Sclerosing Cholangitis-IBD Model
Awoniyi, M.; Meadows, V.; Ngo, B.; Conskuner, D.; Montgomery, S. A.; Farmer, M.; Liu, B.; Zhou, H.; Roach, J.; Stappenbeck, T.; Sartor, B.
10.1101/2024.10.03.616279 — microbiology — Posted on 2024-10-03
4941 Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design
Leddy, O.; Ogongo, P.; Huffaker, J.; Gan, M.; Milligan, R.; Mahmud, S.; Yuki, Y.; Bobosha, K.; Wassie, L.; Carrington, M.; Liu, Q.; Ernst, J. D.; White, F. M.; Bryson, B. D.
10.1101/2024.10.02.616386 — microbiology — Posted on 2024-10-03
4942 Genderized Gut and Oral Microbiome Shifts: Uncovering Sex-Specific Dysbiosis in Pancreatic Cancer
Khan, Z. A.; Ghorbani, M.; Heffinger, L.; Damdimopoulos, A.; Moro, C. F.; Bjornstedt, M.; Lohr, J.- M.; Heuchel, R.; Chen, M. S.; Sarhan, D.
10.1101/2024.10.02.616338 — immunology — Posted on 2024-10-03
4944 Fate plasticity of interneuron specification
Mostajo-Radji, M. A.; Leon, W. R. M.; Breevoort, A.; Gonzalez-Ferrer, J.; Schweiger, H. E.; Lehrer, J.; Zhou, L.; Schmitz, M. T.; Perez, Y.; Mukhtar, T.; Chu, J.; Andrews, M. G.; Sullivan, F. N.; Tejera, D.; Choy, E. C.; Paredes, M. F.; Teodorescu, M.; Kriegstein, A. R.; Alvarez-Buylla, A.; Pollen, A. A.
10.1101/2024.10.02.614266 — neuroscience — Posted on 2024-10-03
4946 Reward processing in children with Affective Dysregulation
Aggensteiner, P. M.; Giller, F.; Holz, N.; Kaiser, A.; Igel, C.; Hohmann, S.; Doepfner, M.; Roessner, V.; Beste, C.; Banaschewski, T.; Brandeis, D.
10.1101/2024.10.02.616272 — neuroscience — Posted on 2024-10-03
4950 Metazoan diversity in Chilean hypersaline lakes unveiled by environmental DNA
Sacco, M.; Campbell, M. A.; Aguilar, P.; Salazar, G.; Berry, T. E.; Heydenrich, M. J.; Lawrie, A.; White, N. E.; Harrod, C.; Allentoft, M. E.
10.1101/2024.10.01.616191 — ecology — Posted on 2024-10-03
4951 Heterogeneity and plasticity of the naive CD4+ T cell compartment
Sajani, A.; Schaafsma, E.; Croteau, W.; Eltanbouly, M.; Nowak, E. C.; Cheng, C.; Burns, C.; Turk, M. J.; Noelle, R. J.; Lines, J. L.
10.1101/2024.10.02.615602 — immunology — Posted on 2024-10-03
4952 A thermoplastic chip for correlative assays combining screening and high-resolution imaging of immune cell responses
van Ooijen, H.; Verron, Q.; Zhang, H.; Sandoz, P. A.; Frisk, T. W.; Carannante, V.; Olofsson, K.; Wagner, A. K.; Sandstrom, N.; Onfelt, B.
10.1101/2024.10.02.616277 — immunology — Posted on 2024-10-03
4953 Pannexin-2 deficient zebrafish develop ocular and visual motor behaviour defects
Shanbhag, R.; Zoidl, G. S. O.; Sabour, S.; Nakhuda, F.; Zoidl, C.; Bahl, A.; Tabatabaei, N.; Zoidl, G. R.
10.1101/2024.10.01.616190 — neuroscience — Posted on 2024-10-03
4954 A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina
Benfenati, F.; Di Marco, S.; Ziraldo, G.; Cupini, S.; Sesti, V.; Delfino, E.; Lanzani, G.; Bertarelli, C.
10.1101/2024.10.02.616298 — neuroscience — Posted on 2024-10-03
4955 Optimal control of spiking neural networks
Costa, T.; Castineiras de Saa, J. R.; Renart, A.
10.1101/2024.10.02.616330 — neuroscience — Posted on 2024-10-03
4956 Pharmacological inhibition of Fms-like kinase 3 (FLT3) promotes neuronal maturation and suppresses seizure in a mouse model
Cruite, K.; Moore, M.; Gallagher, M.; Coleman, E.; Yin, Y.; Lin, S.; Shahbo, E.; Lungjangwa, T.; Hovestadt, V.; Jaenisch, R.; Maguire, J.; Tang, X.
10.1101/2024.10.02.616380 — neuroscience — Posted on 2024-10-03
4958 Dopamine and temporal discounting: revisiting pharmacology and individual differences
Smith, E.; Theis, H.; van Eimeren, T.; Knauth, K.; Tuzsus, D.; Zhang, L.; Mathar, D.; Peters, J.
10.1101/2024.08.28.610170 — neuroscience — Posted on 2024-10-03
4960 Genetic Diversity of Zymoseptoria tritici Populations in Central and South-eastern Ethiopia
Tucho, A.; Mekonnen, T.; Ghadamgahi, F.; Gosh, S.; Muleta, D.; Tesfaye, K.; Wang, E. S.; Alemu, T.; Vetukuri, R. R.
10.1101/2024.10.02.616306 — plant biology — Posted on 2024-10-03
4961 GRIN2B disease-associated mutations disrupt the function of BK channels and NMDA receptor signalling nanodomains
Martinez-Lazaro, R.; Minguez-Vinas, T.; Alvarez de la Rosa, D.; Bartolome-Martin, D.; Giraldez, T.
10.1101/2024.10.02.616357 — physiology — Posted on 2024-10-03
4963 Gas1-Mediated Suppression of Hepatoblastoma Tumorigenesis
Chen, K.; Wang, H.; Ma, B.; Knapp, J.; Henchy, C.; Lu, J.; Stevens, T.; Ranganathan, S.; Prochownik, E. V.
10.1101/2024.10.02.616350 — cancer biology — Posted on 2024-10-03
4964 CREATE: cell-type-specific cis-regulatory elements identification via discrete embedding
Cui, X.; Yin, Q.; Gao, Z.; Li, Z.; Chen, X.; Chen, S.; Liu, Q.; Zeng, W.; Jiang, R.
10.1101/2024.10.02.616391 — bioinformatics — Posted on 2024-10-03
4965 Fully Hyperbolic Neural Networks: A Novel Approach to Studying Aging Trajectories
Ramirez, H.; Tabarelli, D.; Brancaccio, A.; Belardinelli, P.; Marsh, E. B.; Funke, M.; Mosher, J.; Maestu, F.; Xu, M.; Pantazis, D.
10.1101/2024.10.01.616153 — bioinformatics — Posted on 2024-10-03
4966 Mosaic integration of spatial multi-omics with SpaMosaic
Yan, X.; Li, M.; Ang, K. S.; Olst, L. v.; Edwards, A.; Watson, T.; Zheng, R.; Fan, R.; Gate, D.; Chen, J.
10.1101/2024.10.02.616189 — bioinformatics — Posted on 2024-10-03
4971 De-novo Genome of the Edwardsiid anthozoan Edwardsia elegans
Rutlekowski, A.; Modepalli, V.; Ketchum, R.; Moran, Y.; Reitzel, A.
10.1101/2024.10.02.616324 — genomics — Posted on 2024-10-03
4974 Divergence and parallelism in two tropical drosophilids simultaneously invading a desert environment
Elsabrout, A.; Moreno, C.; Temperville, M.; Ferreira, E. A.; Ogereau, D.; Hassani, I. M.; Bastide, H.; Abou-Youssef, A. Y.; Yassin, A.
10.1101/2024.10.02.616270 — evolutionary biology — Posted on 2024-10-03
4975 Metrics based on habitat area and condition are poor proxies for invertebrate biodiversity
Duffus, N. E.; Atkins, T. B.; zu Ermgassen, S. O. S. E.; Grenyer, R.; Bull, J. W.; Castell, D. A.; Stone, B.; Tooher, N.; Milner-Gulland, E. J.; Lewis, O. T.
10.1101/2024.10.02.616290 — ecology — Posted on 2024-10-03
4977 skalo: using SKA split k-mers with coloured de Brujin graphs to genotype indels
Derelle, R.; Madon, K.; Arinaminpathy, N.; Lalvani, A.; Harris, S. R.; Lees, J. A.; Chindelevitch, L.
10.1101/2024.10.02.616334 — microbiology — Posted on 2024-10-03
4978 First versatile reverse genetics system for feline coronavirus
Kida, I.; Tamura, T.; Kuroda, Y.; Fukuhara, T.; Maeda, K.; Matsuno, K.
10.1101/2024.10.02.616382 — microbiology — Posted on 2024-10-03
4980 IL-1β Signaling Modulates T Follicular Helper and Regulatory Cells in Human Lymphoid Tissues
Vaineau, R.; Jeger-Madiot, R.; Ali-Moussa, S.; Prudhomme, L.; Debarnot, H.; Coatnoan, N.; Dubois, J.; Binvignat, M.; Vantomme, H.; Gouritin, B.; Fourcade, G.; Engeroff, P.; Belbezier, A.; Luscan, R.; Denoyelle, F.; Lorenzo, R.; Ribet, C.; Rosenzwajg, M.; Bellier, B.; Klatzmann, D.; Tchitchek, N.; Graff-Dubois, S.
10.1101/2024.10.02.616222 — immunology — Posted on 2024-10-03
4981 PPARγ downregulation in colonic CD8+ T cells results in epithelial barrier disruption in people with HIV on antiretroviral therapy
Das Adhikari, U.; Froehle, L. M.; Pipkin, A. N.; Baharlou, H.; Linder, A. H.; Shah, P.; Hussey, A.; Zhang, Q.; Nyquist, S.; Khwaled, S.; Chi, F.; Goswami, S.; Dieffenbach, T. J.; Read, B. J.; Kim, B.; Irvine, D. J.; Asowata, O.; Ladinsky, M. S.; Bjorkman, P.; Madela, F.; Khader, S.; Shalek, A. K.; Ghebremichael, M.; Kloverpris, H.; Ringel, A.; Yilmaz, O. H.; Kwon, D. S.
10.1101/2024.10.02.616363 — immunology — Posted on 2024-10-03
4982 Advancing Adoptive Cell Therapy: Optimized Expansion of Adaptive NK Cells for Solid Tumors
Almazan, N. M.; Roman, S.; Sun, Y.; Brautigam, L.; Stragliotto, G.; Gultekin, O.; Saheli, S.; Lehti, K.; Naucler, C. S.; Sarhan, D.
10.1101/2024.10.02.616358 — immunology — Posted on 2024-10-03
4983 Tbc1d15 knockdown in vivo alleviates α-synuclein-induced neurotoxicity by promoting autophagy.
Siddiqi, F. H.; Raval, N.; Palner, M.; Nielsen, J. E.; Pocock, R.; Rubinsztein, D. C.; Ejlerskov, P.
10.1101/2024.10.01.616109 — neuroscience — Posted on 2024-10-03
4984 Stimulus history, not expectation, drives sensory prediction errors in mammalian cortex
Westerberg, J. A.; Xiong, Y. S.; Nejat, H.; Sennesh, E.; Durand, S.; Cabasco, H.; Belski, H.; Gillis, R.; Loeffler, H.; Bawany, A.; Peene, C. R.; Han, W.; Nguyen, K.; Ha, V.; Johnson, T.; Grasso, C.; Hardcastle, B.; Young, A.; Swapp, J.; Ouellete, B.; Caldejon, S.; Williford, A.; Groblewski, P. A.; Olsen, S. R.; Kiselycznyk, C.; Lecoq, J. A.; Maier, A.; Bastos, A. M.
10.1101/2024.10.02.616378 — neuroscience — Posted on 2024-10-03
4993 Mitochondrial reactive oxygen species cause arrhythmias in hypertrophic cardiomyopathy
Kohlhaas, M.; Sequeira, V.; Parikh, S.; Dietl, A.; Richter, O.; Bay, J.; Bertero, E.; Schwemmlein, J.; Tian, Q.; Friedrich, F. W.; Flenner, F.; Nickel, A. G.; Alscher, F.; Nanadikar, M. S.; Venkataraman, R.; Baudenbacher, F. J.; Kappl, R.; Johnson, V.; Prates Roma, L.; Kasakow, A.; Hohl, M.; Laufs, U.; Hoth, M.; Katschinski, D. M.; Bohm, M.; Lipp, P.; Carrier, L.; Eschenhagen, T.; Knollmann, B. C.; Maack, C.
10.1101/2024.10.02.616214 — physiology — Posted on 2024-10-03
4995 Comparative analysis of Endoxifen, Tamoxifen and Fulvestrant: A Bioinformatics Approach to Uncover Mechanisms of Action in Breast Cancer
Remmel, H. L.; Hammer, S. S.; Singh, H.; Shneyderman, A.; Veviorskiy, A.; Alawi, K. M.; Korzinkin, M.; Zhavoronkov, A.; Quay, S. C.
10.1101/2024.10.02.616224 — cancer biology — Posted on 2024-10-03
4998 Making Aptamers More Antibody-like: Targeting AXL in Vivo Using a Bottlebrush Polymer-Conjugated Aptamer
Sun, T.; Lin, J.; Xue, C.; Wang, Y.; Chen, P.; Wei, Y.; Xu, G.; Sidonia, A.; Nenopoulos, C.; Tashkandi, H.; Zhang, K.
10.1101/2024.10.02.616316 — cancer biology — Posted on 2024-10-03
4999 CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors
Ruegger, J.; Gagestein, B.; Janssen, A. P. A.; Valeanu, A.; Lazo Mori, A.; van der Peet, M.; Boutkan, M. S.; Florea, B. I.; Henneman, A. A.; Hochstrasser, R.; Wang, H.; Westwood, P.; Topp, A.; Gomez Barila, P. M.; Medema, J. P.; Jimenez, C. R.; Woersdoerfer, B.; Kirchner, S.; Zhang, J. D.; Grether, U.; Rufer, A. C.; van der Stelt, M.
10.1101/2024.10.01.616061 — cancer biology — Posted on 2024-10-03
5001 Atomic-Level Investigation of KCNJ2 Mutations Associated with Ventricular Arrhythmic Syndrome Phenotypes
Munawar, S.; Anderson, C. L.; Reilly, L.; Woltz, R. L.; Kayani, Y. S.; Chiamvimonvat, N.; Eckhardt, L. L.
10.1101/2024.10.01.616187 — biophysics — Posted on 2024-10-03
5002 Illuminating root-soil mechanics
Le Houx, J.; McKay Fletcher, D.; Leonardi, A.; Williams, K.; Walker, N.; Albarez Borges, F.; Afsar Dizaj, E.; Murthy, M.; Smith, R.; Perera, L.; Asiani, N.; James, A.; Ahmed, S.; Roose, T.; Ruiz, S.
10.1101/2024.10.02.616056 — biophysics — Posted on 2024-10-03
5004 Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins
Zakrzewska, S.; Nixon, S. A.; Chen, Z.; Hajare, H. S.; Park, E. R.; Mulcahy, J. V.; Arlinghaus, K. M.; Neu, E.; Konovalov, K.; Provasi, D.; Leighfield, T. A.; Filizola, M.; Du Bois, J.; Minor, D. L.
10.1101/2024.10.01.616181 — biophysics — Posted on 2024-10-03
5005 New Statistical Metric for Robust Target Detection in Cryo-EM Using 2DTM
Zhang, K.; Cossio, P.; Rangan, A. V.; Lucas, B. A.; Grigorieff, N.
10.1101/2024.10.01.616095 — biophysics — Posted on 2024-10-03
5009 PertEval-scFM: Benchmarking Single-Cell Foundation Models for Perturbation Effect Prediction
Wenteler, A.; Occhetta, M.; Branson, N.; Huebner, M.; Curean, V.; Dee, W.; Connell, W.; Hawkins-Hooker, A.; Chung, P.; Ektefaie, Y.; Gallagher-Syed, A.; Valdez Cordova, C. M.
10.1101/2024.10.02.616248 — bioinformatics — Posted on 2024-10-03
5013 A new compression strategy to reduce the size of nanopore sequencing data
Jayasooriya, K.; Jenner, S. P.; Marasinghe, P.; Senanayake, U.; Saadat, H.; Taubman, D.; Ragel, R.; Gamaarachchi, H.; Deveson, I. W.
10.1101/2024.10.02.616377 — bioinformatics — Posted on 2024-10-03
5016 Proteolysis-targeting vaccines (PROTAVs) for robust tumor combination immunotherapy
Wang, Q.; Su, T.; Cheng, F.; Zhou, S.; Liu, X.; Wang, M.; Tang, R.; Xu, Y.; Liao, S.; Dailey, J.; Xiao, G.; Wen, H.; Zheng, w.; Wen, B.; Katarzyna, T. M.; Basrur, V.; Liu, J.; Sun, D.; Wang, S.; Zhu, G.
10.1101/2024.10.01.616069 — bioengineering — Posted on 2024-10-03
5017 Nanoscale biodegradable printing for designed tuneability of vaccine delivery kinetics
Peeler, D. J.; Sun, R.; Kütahya, C.; Peschke, P.; Zhou, K.; Brachi, G.; Yeow, J.; Graham, O. R.; Wojciechowski, J. P.; Debets, T. F.; Lalone, V.; Song, X.; Polra, K.; Tregoning, J. S.; Shattock, R. J.; Stevens, M. M.
10.1101/2024.10.02.616252 — bioengineering — Posted on 2024-10-03
5018 Engineered Whole Lungs for Tissue Biology
Greaney, A. M.; Raredon, M. S. B.; Obata, T.; Wang, J.; Adams, T. S.; Schupp, J. C.; Mizoguchi, S.; Edelstein, S.; Yuan, Y.; Baevova, P.; Wang, N.; Engler, A.; Leiby, K.; Tsuchiya, T.; Homer, R.; Kaminski, N.; Langer, R.; Niklason, L.; Medzhitov, R.
10.1101/2024.10.02.616240 — bioengineering — Posted on 2024-10-03
5019 Digital Light Processing 3D Printing enables High Throughput Fabrication of Human Engineered Heart Tissues for Disease Modeling
Dhand, A. P.; Juarros, M. A.; Martin, T. G.; Rodriguez-Rivera, G. J.; Hunt, D. R.; Obenreder, M. C.; Crosby, C. O.; Meurer-Zeman, B.; McAfee, Q.; Valle-Ayala, H.; Zlotnick, H. M.; Goddard, D. N.; Ebmeier, C. C.; Burdick, J. A.; Leinwand, L. A.
10.1101/2024.10.01.616163 — bioengineering — Posted on 2024-10-03
5020 A low-cost, open-source 3D printer for multimaterial and high-throughput direct ink writing of soft and living materials
Weiss, J. D.; Mermin-Bunnell, A.; Solberg, F. S.; Tam, T.; Rosalia, L.; Sharir, A.; Rutsche, D.; Sinha, S.; Choi, P. S.; Shibata, M.; Palagani, Y.; Nilkant, R.; Paulvannan, K.; Ma, M.; Skylar-Scott, M. A.
10.1101/2024.10.01.615991 — bioengineering — Posted on 2024-10-03
5023 A 3D Image Segmentation Study of U-Net on CT Images of the Human Aorta with Morphologically Diverse Anatomy
Chen, J.; Qian, L.; Wang, P.; Sun, C.; Qin, T.; Kalyanasundaram, A.; Zafar, M.; Elefteriades, J.; Sun, W.; Liang, L.
10.1101/2024.10.02.616348 — bioengineering — Posted on 2024-10-03
5025 Neural population variance explains adaptation differences during learning
Stealey, H. M.; Zhao, Y.; Lu, H.-Y.; Contreras-Hernandez, E.; Chang, Y.-J.; Tobler, P.; Lewis-Peacock, J. A.; Santacruz, S. R.
10.1101/2024.10.01.616115 — bioengineering — Posted on 2024-10-03
5027 Ultrasensitive in vivo infrared spectroscopic imaging via oblique photothermal microscopy
Li, M.; Xiao, S.; Ni, H.; Ding, G.; Yuan, Y.; Marar, C.; Mertz, J.; Cheng, J.-X.
10.1101/2024.10.02.616360 — bioengineering — Posted on 2024-10-03
5028 OpenExo: An Open-Source Modular Exoskeleton to Augment Human Function
Williams, J. R.; Cuddeback, C. F.; Fang, S.; Colley, D.; Enlow, N.; Cox, P.; Pridham, P.; Lerner, Z. F.
10.1101/2024.10.02.616295 — bioengineering — Posted on 2024-10-03
5030 Combined Nanodrops Imaging and Ultrasound Localization Microscopy for Detecting Intracerebral Hemorrhage
LIN, B.-Z.; Fan, A. C.; Wang, Y.; Lowerison, M.; Dong, Z.; You, Q.; Sekaran, N. V. C.; Llano, D. A.; Borden, M. A.; Song, P.
10.1101/2024.10.02.616087 — bioengineering — Posted on 2024-10-03
5035 High-coverage allele-resolved single-cell DNA methylation profiling by scDEEP-mC reveals cell lineage, X-inactivation state, and replication dynamics
Spix, N. J.; Habib, W. A.; Zhang, Z.; Eugster, E.; Milliron, H.-y.; Sokol, D.; Lee, K.-H.; Nolte, P. A.; Endicott, J. L.; Krzyzanowski, K. F.; Hinoue, T.; Morrison, J.; Johnson, B. K.; Zhou, W.; Shen, H.; Laird, P. W.
10.1101/2024.10.01.616139 — genomics — Posted on 2024-10-03
5036 mRNA expression is co-regulated by non-nucleolar RNA polymerase I
Carter, L. M.; Gong, R.; Acosta, N.; Almassalha, L.; Pujadas Liwag, E.; Kuo, T.; Minh Uyen Phan, L.; MacQuarrie, K. L.; Huang, S.; Kanemaki, M.; Backman, V.
10.1101/2024.10.01.615958 — genomics — Posted on 2024-10-03
5038 The Platinum Pedigree: A long-read benchmark for genetic variants
Kronenberg, Z.; Nolan, C.; Mokveld, T.; Rowell, W. J.; Lee, S.; Dolzhenko, E.; Chang, P.-C.; Holt, J. M.; Saunders, C. T.; Olson, N. D.; McGee, S.; Guarracino, A.; Koundinya, N.; Harvey, W. T.; Watkins, W. S.; Munson, K. M.; Hoekzema, K.; Chua, K. P.; Fanslow, C.; Lambert, C.; Dashnow, H.; Garrison, E.; Smith, J.; Lansdorp, P.; Zook, J. M.; Carroll, A.; Jorde, L. B.; Neklason, D. W.; Quinlan, A.; Eichler, E.; Eberle, M. A.
10.1101/2024.10.02.616333 — genomics — Posted on 2024-10-03
5039 Spatial reconstruction of single-cell enhancer activity in a multicellular organism
Alberti, B.; Vincent, S.; Stevant, I.; Lajoignie, D.; Tarayre, H.; Villoutreix, P.; Ghavi-Helm, Y.
10.1101/2024.10.02.616294 — genomics — Posted on 2024-10-03
5040 Temporal High-Resolution Atlas of Human Blood Leukocyte Composition in Response to Respiratory Virus Inoculation
Zhang, Y.; Liu, T.; Liu, C.; Sun, X.; Liu, P.; Hagood, J. S.; Pickles, R. J.; Zou, F.; Zheng, X.
10.1101/2024.10.01.616122 — genomics — Posted on 2024-10-03
5041 Host Genome Drives the Diversity, Richness, and Beneficial Microbes in the Shrimp Microbiota: A Hologenome Perspective.
Cornejo-Granados, F.; Gallardo-Becerra, L.; Romero-Hidalgo, S.; Lopez-Zavala, A. A.; Sotelo-Mundo, R. R.; Cota-Huizar, A.; Ochoa-Leyva, A.
10.1101/2024.10.01.616099 — genomics — Posted on 2024-10-03
5042 The challenge of chromatin model comparison and validation a project from the first international 4D Nucleome Hackathon
Kubica, J.; Korsak, S.; Clerkin, A. B.; Kouril, D.; Schirman, D.; Yadavalli, A. D.; Banecki, K.; Kadlof, M.; Busby, B.; Plewczynski, D.
10.1101/2024.10.02.616241 — genomics — Posted on 2024-10-03
5045 Systematic empirical evaluation of individual base editing targets: validating therapeutic targets in USH2A and comparison of methods
Tachida, Y.; V. Manian, K.; Butcher, R.; Levy, J.; Pendse, N.; Hennessey, E.; Liu, D.; Pierce, E. A.; Liu, Q.; Comander, J.
10.1101/2024.10.02.615422 — genetics — Posted on 2024-10-03
5046 The C. elegans LON-1 protein requires its CAP domain for function in regulating body size and BMP signaling
Serrano, M. V.; Cottier, S.; Wang, L.; Moreira-Antepara, S.; Nzessi, A.; Liu, Z.; Williams, B.; Lee, M.; Schneiter, R.; Liu, J.
10.1101/2024.10.01.616164 — genetics — Posted on 2024-10-03
5047 G4mer: An RNA language model for transcriptome-wide identification of G-quadruplexes and disease variants from population-scale genetic data
Zhuang, F.; Gutman, D.; Islas, N.; Guzman, B. B.; Jimenez, A.; Jewell, S.; Hand, N. J.; Nathanson, K. L.; Dominguez, D.; Barash, Y.
10.1101/2024.10.01.616124 — genetics — Posted on 2024-10-03
5051 Convergent transcriptomic and genomic adaptation in xeric rodents
Chalopin, D.; Rey, C.; Ganofsky, J.; Blin, J.; Chevret, P.; Mouginot, M.; Boussau, B.; Pantalacci, S.; Semon, M.
10.1101/2024.10.02.616319 — evolutionary biology — Posted on 2024-10-03
5052 Ixodes ricinus nymphs prefer blood with Borrelia infection and low corticosteroid concentration
Vanroy, T.; Catfolis, B.; Verbrugghe, E.; Verheyen, K.; Lens, L.; Strubbe, D.; Pasmans, F.; Martel, A.; Croubels, S.; Cherlet, M.; Baeten, L.
10.1101/2024.10.02.616250 — ecology — Posted on 2024-10-03
5055 Seasonal contact and migration structure mass epidemics and inform outbreak preparedness in bottlenose dolphins
Collier, M. A.; Urian, K.; Theisen, S.; Jacoby, A.-M.; Wilkin, S.; Patterson, E. M.; Wallen, M. M.; Colizza, V. A.; Mann, J.; Bansal, S.
10.1101/2024.10.02.616317 — ecology — Posted on 2024-10-03
5057 A spatially-resolved blueprint of the developing human lung reveals a basal cell population regulated by a WNT-driven niche
Hsu, P. P.; Conchola, A. S.; Frum, T.; Dong, X.; Tudrick, L.; Ponnusamy, V.; Downey, M. S.; Wu, M.; Yang, M.; Lee, Y.; Niestroy, E.; Tsai, Y.-H.; Wu, A.; Glass, I. A.; Merajver, S. D.; Spence, J. R.
10.1101/2024.10.01.612096 — developmental biology — Posted on 2024-10-03
5059 Growth compensation upon changes in tissue size in the Drosophila abdomen
Ferreira, A.; Cairoli, A.; Mangione, F.; Holder, M. V.; Ainslie, A.; Aerne, B. L.; Salbreux, G.; Tapon, N.
10.1101/2024.10.02.616326 — developmental biology — Posted on 2024-10-03
5061 Multi-laboratory Study Establishes Reproducible Methods for Plant-Microbiome Research in Fabricated Ecosystems
Novak, V.; Andeer, P. F.; King, E.; Calabria, J.; Fitzpatrick, C.; Kelm, J. M.; Wippel, K.; Kosina, S. M.; Daum, C.; Zane, M.; Yadav, A.; Chen, M.; Russ, D.; Adams, C. A.; Owens, T. K.; Lee, B.; Ding, Y.; Sordo, Z.; Chakraborty, R.; Roux, S.; Deutschbauer, A. M.; Ushizima, D.; Zengler, K.; Arsova, B.; Dangl, J.; Schulze-Lefert, P.; Watt, M.; Vogel, J.; Northen, T. R.
10.1101/2024.10.02.615924 — microbiology — Posted on 2024-10-03
5062 TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differnetiation
Tuomela, K.; Garcia, R. V.; Boardman, D. A.; Tavakoli, P.; Ancheta-Schmit, M.; Sham, H. P.; Chen, L.; Struthers, M.; Bressler, B.; Vallance, B. A.; Zhao, Q.; Levings, M. K.
10.1101/2024.10.01.616157 — immunology — Posted on 2024-10-03
5063 Cryo-EM structural insights into Vγ9Vδ2 TCR activation via multiple butyrophilins
Zhang, M.; Wang, Y.; Cai, N.; Qu, Y.; Ma, X.; Xue, J.; Chen, X.; Zhang, X.; Xiao, J.; Zhang, Y.
10.1101/2024.10.02.616253 — immunology — Posted on 2024-10-03
5067 Immunotherapy with nebulized pattern recognition receptor agonists restores severe immune paralysis and improves outcomes in mice with influenza-associated pulmonary aspergillosis
Garcia, J. P.; Wurster, S.; Albert, N. D.; Bharadwaj, U.; Bhoda, K.; Kulkarni, V.; Ntita, M.; Carstens, P. R.; Burch-Eapen, M.; Lopez, D. C.; Wang, Y.; Kontoyiannis, D. P.; Evans, S. E.
10.1101/2024.10.02.616293 — immunology — Posted on 2024-10-03
5072 Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats
van Rooij, J. R. A.; van den Berg, M.; Vasilkosvka, T.; Van Audekerke, J.; Kosten, L.; Bertoglio, D.; Adhikari, M. H.; Verhoye, M.
10.1101/2024.10.02.616243 — neuroscience — Posted on 2024-10-03
5073 Afternoon to early evening bright light exposure reduces later melatonin production in adolescents
Lazar, R.; Fazlali, F.; Dourte, M.; Epple, C.; Stefani, O.; Spitschan, M.; Cajochen, C.
10.1101/2024.10.02.616112 — neuroscience — Posted on 2024-10-03
5074 Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations
Feczko, E. J.; Stoyell, S. M.; Moore, L. A.; Alexopoulos, D.; Bagonis, M.; Barrett, K.; Bower, B.; Cavender, A.; Chamberlain, T. A.; Conan, G.; Day, T. K.; Goradia, D.; Graham, A.; Heisler-Roman, L.; Hendrickson, T. J.; Houghton, A.; Kardan, O.; Kiffmeyer, E. A.; Lee, E. G.; Lundquist, J. T.; Lucena, C.; Martin, T.; Mummaneni, A.; Myricks, M.; Narnur, P.; Perrone, A. J.; Reiners, P.; Rueter, A. R.; Saw, H.; Styner, M.; Sung, S.; Tiklasky, B.; Wisnowski, J. L.; Yacoub, E.; Zimmermann, B.; Smyser, C. D.; Rosenberg, M. D.; Fair, D. A.; Elison, J. T.
10.1101/2024.10.02.616147 — neuroscience — Posted on 2024-10-03
5075 Physiological and injury-induced microglial dynamics across the lifespan
Tieu, T.; Cruz, A.-J. N.; Weinstein, J. R.; Shih, A.; Coelho-Santos, V.
10.1101/2024.10.02.615212 — neuroscience — Posted on 2024-10-03
5076 Does sex matter in neurons response to hypoxic stress?
Voogd, E. J. H. F.; Levers, M. R.; Hofmeijer, J.; Frega, M.; van Putten, M. J. A. M.
10.1101/2024.10.02.616233 — neuroscience — Posted on 2024-10-03
5077 Spectral estimation at the edge
Patel, S.; Psarou, E.; Mönke, G.; Fries, P.
10.1101/2024.10.02.616083 — neuroscience — Posted on 2024-10-03
5083 Brain Structural Organization Revealed by Unbiased Cell-Type Distribution Clustering
Munoz-Castaneda, R.; Palaniswamy, R.; Palmer, J.; Drewes, R.; Elowsky, C.; Hirokawa, K. E.; Cain, N.; Venkataraju, K. U.; Harris, J. A.; Osten, P.
10.1101/2024.10.02.615922 — neuroscience — Posted on 2024-10-03
5085 Motor Imagery Improves Force Control in Older and Young Females
Calkins, C. A.; Kraeutner, S. N.; McNeil, C. J.; Jakobi, J. M.
10.1101/2024.10.02.616364 — neuroscience — Posted on 2024-10-03
5086 Onco-fetal protein Nogo-A restricts human and mouse glioma vascularization and growth via VEGF-Notch-hippo-metabolic signaling
Schwab, M.; Ghobrial, M.; Macias, J. J.; Beffinger, M.; Ji, Y.; Wacker, A.; Harada, H.; Shiu, J.-Y.; Novitzki, O.; De Trizio, I.; Girolamo, F.; Errede, M.; Weiss, T.; Gramatzki, D.; Maurer, M.; Weinmann, O.; Vogel, V.; Radovanovic, I.; Schwab, M.; Dahmane, N.; Greenfield, J.; Chiocca, A. E.; Virgintino, D.; Weller, M.; vom Berg, J.; Vogel, J.; Davuluri, R. V.; Frei, K.; Schlapbach, R.; De Bock, K.; Monnier, P. p.; Lawler, S. E.; Walchli, T.
10.1101/2024.10.02.616320 — neuroscience — Posted on 2024-10-03
5088 Co-cultivation with Azolla affects the metabolome of whole rice plant beyond canonical inorganic nitrogen fertilization
Consorti, E.; Costarelli, A.; Cannavo, S.; Cerri, M.; Valeri, M. C.; Reale, L.; Saccomanno, A.; Paleni, C.; Gregis, V.; Kater, M. M.; Brilli, F.; Paolocci, F.; Ghirardo, A.
10.1101/2024.10.02.615589 — plant biology — Posted on 2024-10-03
5089 Co-cultivating rice plants with Azolla filiculoides modifies root architecture and timing of developmental stages
Cannavo', S.; Paleni, C.; Costarelli, A.; Valeri, M. C.; Cerri, M.; Gregis, V.; Chini Zittelli, G.; Dobrev, P. I.; Reale, L.; Kater, M. M.; Paolocci, F.
10.1101/2024.10.02.615985 — plant biology — Posted on 2024-10-03
5091 Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae
Priego-Cubero, S.; Knoch, E.; Wang, Z.; Alseekh, S.; Braun, K. H.; Chapman, P.; Fernie, A. R.; Liu, C.; Becker, C.
10.1101/2024.10.02.615186 — plant biology — Posted on 2024-10-03
5092 Potent and durable gene modulation in heart and muscle with chemically defined siRNAs
Fakih, H. H.; Lochmann, C.; Gagnon, R.; Summers, A.; Caiazzi, J.; Buchwald, J. E.; Tang, Q.; Maru, B.; Hildebrand, S. R.; Zain UI Abideen, M.; Furgal, R. C.; Gross, K. Y.; Yang, Y.-S.; Cooper, D.; Monopoli, k.; Echeverria, D.; Shim, J.-h.; Yamada, K.; Alterman, J. F.; Khvorova, A.
10.1101/2024.10.01.616183 — pharmacology and toxicology — Posted on 2024-10-03
5093 Fourth generation CAR Tregs with PDCD1-driven IL-10 have enhanced suppressive function
Boardman, D. A.; Mangat, S.; Gillies, J. K.; Fung, V. C.; Haque, M.; Mojibian, M.; Tuomela, K.; Wardell, C. M.; Brown, A.; Lam, A. J.; Levings, M. K.
10.1101/2024.10.01.616177 — immunology — Posted on 2024-10-03
5094 Brainstem neurons coordinate the bladder and urethra sphincter for urination
Li, X.; Li, X.; Li, J.; Qin, H.; Liang, S.; Li, J.; Jian, T.; Wang, X.; Yin, L.; Yuan, C.; Liao, X.; Jia, H.; Chen, X.; Yao, J.
10.1101/2024.10.01.616107 — neuroscience — Posted on 2024-10-03
5098 Synthetic chaperone based on Hsp90-Tau interaction inhibits pathological Tau aggregation and rescues physiological Tau-Microtubule interaction
Di Lorenzo, D.; Bisi, N.; Kaffy, J.; Ramirez, L. M.; Zweckstetter, M.; Lequin, O.; Garfagnini, I.; Luo, J.; Hannappel, Y.; Ennen, I.; Dodero, V.; Sewald, N.; Gelmi, M. L.; Tonali, N.; Brandt, R.; ONGERI, S.
10.1101/2024.10.01.615850 — pharmacology and toxicology — Posted on 2024-10-03
5100 Regulatory T cells crosstalk with tumor and endothelium through lymphotoxin signaling
Piao, W.; Wu, l.; Xiong, Y. S.; Zapas, G. C.; Paluskievicz, C. M.; Oakes, R. S.; Pettit, S. M.; Schmitz, J.; Shetty, A. C.; Yang, S.; kong, D.; Sleeth, M.; Hippen, K. L.; Li, L.; Lee, Y.; Shirkey, M. W.; Kensiski, A.; Alvi, A.; Ho, K.; Saxena, V.; Brasen, J. H.; Jewell, C. M.; Blazar, B. R.; Abdi, R.; Bromberg, J. S.
10.1101/2024.10.01.616077 — cancer biology — Posted on 2024-10-03
5102 Ultrasound inhibits SARS-CoV-2 infectivity in vitro
Veras, F. P.; Nakamura, G.; Pereira-da-Silva, M. A.; Martins, R.; Arruda, E.; Cunha, F. Q.; Bruno, O. M.
10.1101/2022.11.21.517338 — biophysics — Posted on 2024-10-03
5105 ProteusAI: An Open-Source and User-Friendly Platform for Machine Learning-Guided Protein Design and Engineering
Funk, J.; Machado, L.; Bradley, S. A.; Napiorkowska, M.; Gallegos-Dextre, R.; Pashkova, L.; Madsen, N. G.; Webel, H.; Phaneuf, P. V.; Jenkins, T. P.; Acevedo-Rocha, C. G.
10.1101/2024.10.01.616114 — bioinformatics — Posted on 2024-10-03
5106 A simple action reduces food intake and obesity in mice
Barrett, M. R.; Pan, Y.; Murrell, C.; Karolczak, E. O.; Wang, J.; Fang, L.; Thompson, J. M.; Chang, S.; Casey, E.; Czarny, J.; So, W. L.; Reichenbach, A.; Stark, R.; Taghipourbibalan, H.; Penna, S. R.; McCullough, K. B.; Westbrook, S.; Matikainen-Ankeny, B.; Cazares, V. A.; Delevich, K.; Fobbs, W.; Maloney, S.; Sutton Hickey, A.; McCutcheon, J. E.; Andrews, Z.; Creed, M.; Kravitz, A. V.
10.1101/2024.10.01.615599 — animal behavior and cognition — Posted on 2024-10-03
5108 An inducible and reversible system to regulate unsaturated fatty acid biosynthesis in C. elegans
Battista, B.; Hernandez-Cravero, B.; Colaiacovo, M. P.; Cochella, L.; Binolfi, A.; de Mendoza, D.
10.1101/2024.10.01.616130 — genetics — Posted on 2024-10-03
5111 Accuracy in bird predation assessment: Camera traps testing the efficacy of plasticine caterpillars as prey models
SCHILLE, L.; PLAT, N.; BARBARO, L.; JACTEL, H.; RASPAIL, F.; RIVOAL, J.-B.; CASTAGNEYROL, B.; MRAZOVA, A.
10.1101/2024.10.01.616075 — ecology — Posted on 2024-10-03
5113 A three-country analysis of the gut microbiome indicates taxon associations with diet vary by location and strain
Khatib, L.; Song, S. J.; Dilmore, A. H.; Sanders, J. G.; Brennan, C.; Hernandez, A. R.; Myers, T.; Oles, R.; Farmer, S.; Cowart, C.; Birmingham, A.; Diaz, E. A.; Nizet, O.; Gilbert, K.; Litwin, N.; Das, P.; Nowinski, B.; Bryant, M.; Tribelhorn, C.; Sanders-Bodai, K.; Chaumont, S.; Knol, J.; Roeselers, G.; Laiola, M.; Shetty, S. A.; Veiga, P.; Tap, J.; Derrien, M.; Koutnikova, H.; Cotillard, A.; Lay, C.; Tovar, A. R.; Torres, N.; Arteaga, L.; Gonzalez, A.; McDonald, D.; Bartko, A.; Knight, R.
10.1101/2024.10.01.616090 — microbiology — Posted on 2024-10-03
5114 Environmental matrix and moisture are key determinants of microbial phenotypes expressed in a reduced complexity soil-analog
Rodriguez-Ramos, J. A.; Sadler, N.; Zageye, E. K.; Farris, Y.; Purvine, S. O.; Couvillion, S. P.; Nelson, W. C.; Hofmockel, K.
10.1101/2024.10.02.616266 — microbiology — Posted on 2024-10-03
5116 Differential composition of lymphocyte subpopulations and activation between the hypertensive Bph/2 and normotensive Bpn/3 mouse strains
Dattmore, D. A.; McDonald, P.; Chowdhury, A.; Awali, S.; Boss, A. P.; Jin, Y.; Sather, L.; Lauver, D. A.; Rockwell, C. E.
10.1101/2024.10.01.616072 — immunology — Posted on 2024-10-03
5117 Detecting the bodys reproductive hormonal brake against tissue overgrowth: micrin/SgII-70
Hart, J. E.; Davies, K.; mundy, c. R.; Hart, A.; Howlett, D. R.; Newton, R. P.
10.1101/2024.10.01.616062 — immunology — Posted on 2024-10-03
5122 The PHD3-FOXO3 axis modulates the interferon type I response in microglia aggravating Alzheimer's disease progression
Sanchez-Garcia, M. A.; Lara-Urena, N.; March-Diaz, R.; Ortega-de San Luis, C.; Quinones-Canete, S.; Barba-Reyes, J. M.; Cabello-Rivera, D.; Munoz-Cabello, A. M.; Mora-Romero, B.; Romero-Molina, C.; Heras-Garvin, A.; Navarro, V.; Lopez-Barneo, J.; Vizuete, M.; Vitorica, J.; Munoz-Machado, A. B.; Cockman, M.; Rosales-Nieves, A. E.; Pascual, A.
10.1101/2024.10.01.616066 — neuroscience — Posted on 2024-10-03
5124 Structural proteomics defines a sequential priming mechanism for the progesterone receptor
Mann, M. D.; Wang, M.; Ferreon, J. C.; Suess, M. P.; Jain, A.; Malovannaya, A.; Vera Alvarez, R.; Pascal, B. D.; Kumar, R.; Edwards, D. P.; GRIFFIN, P. R.
10.1101/2024.09.06.611729 — biochemistry — Posted on 2024-10-03
5126 Discovery of a new Phenuivirus species in Lachenalia plants reveals possible co-evolution between 5' and 3' RNA sequence motifs
Dekker, R. J.; de Leeuw, W. C.; van Olst, M.; Ensink, W. A.; van Leeuwen, S.; Breit, T. M.; Jonker, M. J.
10.1101/2024.09.04.611151 — genomics — Posted on 2024-10-03
5127 GLA-3 Mediates Stress Response in Caenorhabditis elegans Germ Cells: A key role of the Tristetraprolin (TTP) Family
Salinas, L. S.; Damazo-Hernandez, A. A.; Morales-Oliva, E. E.; Lascarez-Lagunas, L. I.; Navarro, R. E.
10.1101/2024.10.01.616206 — cell biology — Posted on 2024-10-03
5131 Allosteric regulation of BH3-in-groove interactions by tail anchors of BCL-xL complexes limits BH3 mimetic antagonism.
Maillet, L.; Fetiveau, A.; Lalier, L.; Barille-Nion, S.; Guette, C.; Gautier, F.; Teletchea, S.; Juin, P. P.
10.1101/2024.10.02.616265 — cell biology — Posted on 2024-10-03
5132 Sperm fertility restoration in mice suffering from oligo-astheno-teratozoospermia by in vivo injection and electroporation of naked mRNA
Vilpreux, C.; Martinez, G.; Fourquin, P.; Court, M.; Appaix, F.; Duteyrat, J. L.; Henry, M.; Vollaire, J.; Ayad, C.; Yavuz, A.; De Macedo, L.; Chevalier, G.; Del Llano, E.; Lambert, E.; Ahmed Conte, S.; Wehbe, Z.; Giordani, E.; Josserand, V.; Brocard, J.; Coutton, C.; Verrier, B.; Ray, P. F.; Loeuillet, C.; Arnoult, C.; Escoffier, J.
10.1101/2023.12.12.571239 — molecular biology — Posted on 2024-10-03
5134 Integrating Data Across Oscillatory Power Bands Predicts the Epileptogenic Zone: the Frequency Range Explorer Epileptogenic Zone (FREEZ) Identification Algorithm
O'Leary, S.; Lesage, A.-C.; Camarillo-Rodriguez, L.; Zhou, O.; Silveira, D.; Wang, J.; Sheth, S.; Beauchamp, M. S.; Wang, Z.; Magnotti, J. F.; Karas, P. J.
10.1101/2024.05.31.596825 — neuroscience — Posted on 2024-10-03
5140 Lumen charge governs memristive ion transport in β-barrel nanopores
Mayer, S. F.; Mitsioni, M.; van den Heuvel, L.; Robin, P.; Ronceray, N.; Marcaida, M. J.; Abriata, L. A.; Krapp, L. F.; Anton, J. S.; Soussou, S.; Jeanneret-Grosjean, J.; Fulciniti, A.; Moller, A.; Vacle, S.; Feletti, L.; Brinkerhoff, H.; Laszlo, A. H.; Gundlach, J. H.; Emmerich, T.; Dal Peraro, M.; Radenovic, A.
10.1101/2024.09.26.615172 — biophysics — Posted on 2024-10-03
5142 ClassiCOL: LC-MS/MS analysis for ancient species Classification via Collagen peptide ambiguation
Engels, I.; Burnett, A.; Robert, P.; Pironneau, C.; Abrams, G.; Bouwmeester, R.; Van der Plaatsen, P.; Di Modica, K.; Otte, M.; Straus, L. G.; Fischer, V.; Bray, F.; Mesuere, B.; De Groote, I.; Deforce, D.; Daled, S.; Dhaenens, M.
10.1101/2024.10.01.616034 — bioinformatics — Posted on 2024-10-03
5144 RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets
Hemm, L.; Rabsch, D.; Ropp, H. R.; Reimann, V.; Gerth, P.; Bartel, J.; Brenes, M.; Maass, S.; Becher, D.; Hess, W. R.; Backofen, R.
10.1101/2024.09.30.615781 — bioinformatics — Posted on 2024-10-03
5145 Adjuvant Delivery Method and Nanoparticle Charge Influence Peptide Amphiphile Micelle Vaccine Bioactivity
Zhang, R.; Rygelski, B. T.; Kruse, L. E.; Smith, J. D.; Wang, X.; Allen, B. N.; Kramer, J. S.; Seim, G. F.; Faulkner, T. J.; Kuang, H.; Kokkoli, E.; Schrum, A. G.; Ulery, B. D.
10.1101/2024.06.10.598369 — bioengineering — Posted on 2024-10-03
5146 Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
Chen, M.; Nguyen, T. N.; Ren, X.; Khuu, G.; Cook, A. S. I.; Zhao, Y.; Yildiz, A.; Lazarou, M.; Hurley, J. H.
10.1101/2023.06.01.543278 — biochemistry — Posted on 2024-10-03
5147 The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation
Kosch, T. A.; Torres-Sanchez, M.; Liedtke, H. C.; Summers, K.; Yun, M. H.; Crawford, A. J.; Maddock, S. T.; Ahammed, M. S.; Araujo, V. L. N.; Vincenzo Bertola, L.; Bucciarelli, G. M.; Carne, A.; Carneiro, C. M.; Chan, K. O.; Chen, Y.; Crottini, A.; da Silva, J. M.; Denton, R. D.; Dittrich, C.; Espregueira Themudo, G.; Farquharson, K. A.; Forsdick, N. J.; Gilbert, E.; Che, J.; Katzenback, B. A.; Kotharambath, R.; Levis, N. A.; Marquez, R.; Mazepa, G.; Mulder, K. P.; Müller, H.; O'Connell, M. J.; Orozco-terWengel, P.; Palomar, G.; Petzold, A.; Pfennig, D. W.; Pfennig, K. S.; Reichert, M. S.; Ro
10.1101/2024.06.27.601086 — genomics — Posted on 2024-10-03
5148 A new Betaflexivirus species in Ferraria crispa plants
Dekker, R. J.; de Leeuw, W. C.; van Olst, M.; Ensink, W. A.; van Leeuwen, S.; Breit, T. M.; Jonker, M. J.
10.1101/2024.09.02.610804 — genomics — Posted on 2024-10-03
5149 RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation
Ganguli, S.; Gupta, D.; Ramaswamy, R.; Kadumuri, R. V.; Krishnan, A. G.; Tandel, D.; David, D. T.; Bunk, S.; Chavali, S.; Harshan, K.; Chavali, P. L.
10.1101/2024.09.29.615653 — cell biology — Posted on 2024-10-03
5152 Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
Worrell, J. C.; Hargrave, K. E.; Finney, G. E.; Hansell, C.; Cole, J. J.; Singh Niijar, J.; Morton, F. R.; Pingen, M.; Purnell, T.; Mitchelson, K.; Brennan, E.; Allan, J.; Ilia, G.; Herder, V.; Kennedy Dietrich, C.; Doncheva, Y.; Jamieson, N.; Palmarini, M.; MacLeod, M. K.
10.1101/2024.07.20.604410 — immunology — Posted on 2024-10-03
5153 Regulation of dopamine release by tonic activity patterns in the striatal brain slice
Boumhaouad, S.; Makowicz, E. A.; Choi, S.; Bouhaddou, N.; Balla, J.; Taghzouti, K.; Sulzer, D.; Mosharov, E.
10.1101/2024.05.22.595411 — neuroscience — Posted on 2024-10-03
5155 Neuronal activity regulating the dauer entry decision in Caenorhabditis elegans
Prakash, S. J.; Seyedolmohadesin, M.; Zhang, M. G.; Cohen, S. M.; Gharib, S.; Venkatachalam, V.; Sternberg, P. W.
10.1101/2024.09.30.615551 — neuroscience — Posted on 2024-10-03
5156 Layer-specific input to medial prefrontal cortex is linked to stress susceptibility
Solakoglu, S. T.; Erdener, S. E.; Gliko, O.; Can, A.; Sumbul, U.; Eren-Kocak, E.
10.1101/2024.04.03.587746 — neuroscience — Posted on 2024-10-03
5159 Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
Williams, J.; Camarda, R.; Malkov, S.; Zimmerman, L. J.; Manning, S.; Aran, D.; Beardsley, A.; Van de Mark, D.; Chen, Y.; Berdan, C. A.; Louie, S. M.; Mahieu, C.; Superville, D.; Winkler, J.; Willey, E.; Gagnon, J. D.; Avsaroglu, S. K.; Shinoda, K.; Gruner, M.; Nishida, H.; Ansel, K. M.; Werb, Z.; Nomura, D. K.; Kajimura, S.; Butte, A. J.; Sanders, M. E.; Liebler, D. C.; Rugo, H.; Krings, G.; Shepherd, J. A.; Goga, A.
10.1101/277939 — cancer biology — Posted on 2024-10-03
5160 Soil biodiversity in the Atacama Desert shows distinct patterns at different diversity levels
Villegas, L.; Pettrich, L.; Acevedo-Trejos, E.; Suwanngam, A.; Wassey, N.; Allende, M. L.; Stoll, A.; Holovachov, O.; Waldvogel, A.-M.; Schiffer, P. H.
10.1101/2024.09.30.615889 — ecology — Posted on 2024-10-03
5161 The contribution of aquatic foods to human nutrient intake and adequacy in a Small Island Developing State
Zamborain-Mason, J.; Eurich, J. G.; Friedman, W. R.; Gephart, J. A.; Kelahan, H. M.; Seto, K. L.; Andrew, N. L.; Sharp, M. K.; Tekaieti, A.; Timeon, E.; Golden, C. D.
10.1101/2024.10.02.616287 — ecology — Posted on 2024-10-03
5163 Decreased hippocampal neurite density in middle-aged/aging adults following prenatal exposure to higher levels of maternal inflammation
Mohyee, R. A.; Elliott, B. L.; Pike, M. R.; Smith, E.; Kring, A. M.; Olson, I. R.; Breen, E. C.; Cohn, B. A.; Cirillo, P. M.; Krigbaum, N. Y.; Olino, T. M.; D'Esposito, M.; Cogan, A. B.; Patwardan, B. P.; Ellman, L. M.
10.1101/2024.10.01.616156 — immunology — Posted on 2024-10-03
5164 Rapamycin Immunomodulation Utilizes Time-Dependent Alterations of Lymph Node Architecture, Leukocyte Trafficking, and Gut Microbiome
Wu, L.; Kensiski, A.; Gavzy, S.; Lwin, H. W.; Song, Y.; France, M.; Lakhan, R.; Kong, D.; Li, L.; Saxena, V.; Piao, W.; Shirkey, M.; Mas, V.; Ma, B.; Bromberg, J.
10.1101/2024.10.01.616121 — immunology — Posted on 2024-10-03
5165 Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia
Memel, M.; Staffaroni, A.; Ilan-Gala, I.; Garcia Castro, J.; Kornak, J.; Tartaglia, C.; Saloner, R.; VandeBunte, A.; Paolillo, E.; Cadwallader, C.; Chen, C.; Gorno-Tempini, M. L.; Mandelli, M.; Apostolova, L.; Graff-Radford, N.; Litvan, I.; Bayram, E.; Pressman, P.; Miyagawa, T.; Mackenzie, I.; Goldman, J.; Darby, R.; Appleby, B.; Petrucelli, L.; Gendron, T.; Heuer, H.; Forseberg, L.; Rojas, J.; Boeve, B.; Brushaber, N.; Domoto-Reilly, K.; Ghoshal, N.; Lapid, M.; Pascual, B.; Lee, S.; Ramos, E.; Ramanan, V.; Rademakers, R.; Rascovsky, K.; Pantelyat, A.; Masdeu, J.; Snyder, A.; Boxer, A.; Rosen
10.1101/2024.10.01.614851 — neuroscience — Posted on 2024-10-03
5167 Expectation elicits music-evoked chills
de Fleurian, R.; Clemente, A.; Benetos, E.; Pearce, M.
10.1101/2024.10.02.616280 — neuroscience — Posted on 2024-10-03
5177 Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDA{varphi}
Boehning, J.; Graham, M.; Coureuil, M.; Tarafder, A. K.; Meyer, J.; Nassif, X.; Bille, E.; Bharat, T. A. M.
10.1101/2024.10.02.616247 — microbiology — Posted on 2024-10-02
5180 Urinary Sodium Wasting and Disrupted Collecting Duct Function in Mice with dRTA-Causing SLC4A1 Mutations
Mungara, P.; MacNaughton, K.; Ullah, A. S.; Essuman, G.; Chelangarimiyandoab, F.; Mumtaz, R.; Hennings, J. C.; Hubner, C. A.; Eladari, D.; Alexander, R. T.; Cordat, E.
10.1101/2024.08.21.608692 — physiology — Posted on 2024-10-02
5184 Ternary complex formation of VCP, VCPIP1 and p47 facilitates Golgi reassembly
Shah, B.; Hunkeler, M.; Bratt, A.; Yue, H.; Jaen Maisonet, I.; Fischer, E. S.; Buhrlage, S. J.
10.1101/2024.10.01.616120 — biochemistry — Posted on 2024-10-02
5188 MORC-1 is a key component of the C. elegans CSR-1 germline gene licensing mechanism
Kirshner, J. A.; Picard, C. L.; Weiser, N. E.; Mehta, N.; Feng, S.; Murphy, V. N.; Vakhnovetsky, A.; Alessi, A. F.; Xiao, C.; Inoki, K.; El Mouridi, S.; Frokjaer-Jensen, C.; Jacobsen, S. E.; Kim, J. K.
10.1101/2024.10.02.616347 — molecular biology — Posted on 2024-10-02
5189 A comprehensive multi-omics signature of doxorubicin-induced cellular senescence in the postmenopausal human ovary.
Devrukhkar, P. R.; Watson, M.; Soygur, B.; Wu, F.; Bons, J.; Anvari, H.; Atazhanova, T.; Martin, N.; Tran, T.; Schneider, K.; Rose, J. P.; Shanes, E.; Pavone, M. E.; Campisi, J.; Furman, D.; Melov, S.; Schilling, B.; Duncan, F. E.
10.1101/2024.10.02.616143 — molecular biology — Posted on 2024-10-02
5194 Mechanism of DNA entrapment by the MukBEF SMC complex and its inhibition by a viral DNA mimic
Bürmann, F.; Clifton, B.; Koekemoer, S.; Wilkinson, O. J.; Kimanius, D.; Dillingham, M. S.; Löwe, J.
10.1101/2024.10.02.616235 — molecular biology — Posted on 2024-10-02
5195 Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system
Sailer, A.-L.; Brendel, J.; Chernev, A.; Koenig, S.; Bischler, T.; Graefenhan, T.; Urlaub, H.; Gophna, U.; Marchfelder, A.
10.1101/2024.10.02.616218 — molecular biology — Posted on 2024-10-02
5198 Soil depth determines the microbial communities in Sorghum bicolor fields
Murray, E. R.; Minich, J. J.; Saxton, J.; de Gracia, M.; Eck, N.; Allsing, N.; Kitony, J.; Patel-Jhawar, K.; Allen, E. E.; Michael, T. P.; Shakoor, N.
10.1101/2024.10.02.616346 — microbiology — Posted on 2024-10-02
5203 Soft X-ray tomography reveals variations in B.subtilis biofilm structure upon tasA deletion
Chatzimpinou, A.; Diehl, A.; Harhoff, T.; Driller, K.; Vanslembrouck, B.; Chen, J.-H.; Kairiss, K.; Loconte, V.; Le Gros, M.; Larabell, C. A.; Turgay, K.; Oschkinat, H.; Weinhardt, V.
10.1101/2024.10.01.615898 — microbiology — Posted on 2024-10-02
5205 A dopaminergic basis of behavioral control
Ballard, I. C.; Furman, D. J.; Berry, A. S.; White, R. L.; Jagust, W. J.; Kayser, A. S.; D'Esposito, M.
10.1101/2024.09.17.613524 — neuroscience — Posted on 2024-10-02
5207 Generalizable gesture recognition usingmagnetomyography
Yun, R.; Csaky, R.; Dash, D.; Gerrard, I.; Gonzalez, G.; Kittle, E.; Taylor, D.; Soroushmojdehi, R.; Labanowski, D.; Deka, N.
10.1101/2024.09.30.615946 — neuroscience — Posted on 2024-10-02
5209 Engineering synthetic agonists for targeted activation of Notch signaling
Perez, D. H.; Antfolk, D.; Medina, E.; Gonzalez-Perez, D.; Luca, V. C.; Bustos, X. E.; Chang, S.; Ramadan, A. A.; Rodriguez, P. C.; Abate-Daga, D.
10.1101/2024.08.06.606897 — synthetic biology — Posted on 2024-10-02
5211 Unraveling lncRNA Diversity at a Single Cell Resolution and in a Spatial Context across Different Cancer Types
Prakrithi, P.; Vo, T.; Vu, H.; Xiong, Z.; Nguyen, L. T.; Newman, A.; Whitehall, V.; Gonzalez Cruz, J. L.; Gupta, I.; Nguyen, Q.
10.1101/2024.08.12.607523 — cancer biology — Posted on 2024-10-02
5212 Cluster size determines morphology of transcription factories in human cells
Semeraro, M.; Negro, G.; Forte, G.; Suma, A.; Gonnella, G.; Cook, P. R.; Marenduzzo, D.
10.1101/2023.01.16.524198 — biophysics — Posted on 2024-10-02
5215 HERMES: Holographic Equivariant neuRal network model for Mutational Effect and Stability prediction
Visani, G. M.; Pun, M. N.; Galvin, W.; Daniel, E.; Borisiak, K.; Wagura, U.; Nourmohammad, A.
10.1101/2024.07.09.602403 — bioinformatics — Posted on 2024-10-02
5216 Structural basis of SARS-Cov-2 spike recognition by engineered synthetic multivalent VHH antibodies
Lujan Hernandez, A. G.; Laughlin, Z. T.; Patel, A.; Yuan, T. Z.; Nugent, R. L.; Axelrod, F.; Ortlund, E. A.; Sato, A. K.
10.1101/2024.10.02.616254 — bioengineering — Posted on 2024-10-02
5217 Development of potent and selective CK1α Molecular Glue Degraders
Geng, Q.; Jiang, Z.; Byun, W. S.; Donovan, K. A.; Zhuang, Z.; Jiang, F.; Jones, H. M.; Razumkov, H.; Tang, M. T.; Sarott, R. C.; Fischer, E. S.; Corsello, S. M.; Hinshaw, S. M.; Gray, N. S.
10.1101/2024.10.01.616159 — biochemistry — Posted on 2024-10-02
5218 Autophosphorylation of the oncogenic protein TEL-ABL confers resistance to the allosteric ABL inhibitor asciminib
Muratcioglu, S.; Eide, C. A.; Gorday, K.; Sumpena, E.; Zuo, W.; Groves, J. T.; Druker, B. J.; Kuriyan, J.
10.1101/2024.10.02.616342 — biochemistry — Posted on 2024-10-02
5219 Cryo-EM structures of G4-stalled CMG reveal inchworm mechanism of DNA translocation
Batra, S.; Allwein, B.; Kumar, C.; Devbhandari, S.; Bruning, J.-G.; Bahng, S.; Lee, C.; Marians, K. J.; Hite, R. K.; Remus, D.
10.1101/2024.10.02.616340 — biochemistry — Posted on 2024-10-02
5220 In-gel refolding allows fluorescence detection of fully denatured GFPs after SDS-PAGE
Shiratori, M.; Tsuyuki, R.; Asanuma, M.; Kawabata, S.; Yoshioka, H.; Ohgane, K.
10.1101/2024.10.02.615947 — biochemistry — Posted on 2024-10-02
5221 Sperm competition intensity shapes divergence in both sperm morphology and reproductive genes across murine rodents
Kopania, E. E. K.; Thomas, G. W. C.; Hutter, C. R.; Mortimer, S. M. E.; Callahan, C. M.; Roycroft, E.; Achmadi, A. S.; Breed, W. G.; Clark, N. L.; Esselstyn, J. A.; Rowe, K. C.; Good, J. M.
10.1101/2023.08.30.555585 — evolutionary biology — Posted on 2024-10-02
5222 One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation
Paillet, Y.; Zapponi, L.; Schall, P.; Monnet, J.-M.; Ammer, C.; Balducci, L.; Boch, S.; Brazaitis, G.; Campanaro, A.; Chianucci, F.; Doerfler, I.; Fischer, M.; Gosselin, M.; Gossner, M. M.; Heilmann-Clausen, J.; Hofmeister, J.; Hosek, J.; Jung, K.; Kepfer-Rojas, S.; Odor, P.; Tinya, F.; Trentanovi, G.; Vacchiano, G.; Vandekerkhove, K.; Weisser, W. W.; Wohlwend, M.; Burrascano, S.
10.1101/2024.02.12.579875 — ecology — Posted on 2024-10-02
5223 Breathing in sync: how a social behavior structures respiratory epidemic risk in bottlenose dolphins
Collier, M. A.; Jacoby, A.-M.; Foroughirad, V.; Patterson, E. M.; Krzyszczyk, E.; Wallen, M. M.; Miketa, M.; Karniski, C.; Wilkin, S.; Mann, J.; Bansal, S.
10.1101/2023.12.01.569646 — ecology — Posted on 2024-10-02
5224 E4F1 COORDINATES PYRUVATE METABOLISM AND THE ACTIVITY OF THE ELONGATOR COMPLEX TO ENSURE TRANSLATION FIDELITY DURING BRAIN DEVELOPMENT
DiMichele, M.; Attina, A.; Roux, P. F.; Tabet, I.; Laguesse, S.; Florido, J.; Houdeville, M.; Choquet, A.; Encislai, B.; Arena, G.; DeBlasio, C.; Wendling, O.; Frenois, F. X.; Papon, L.; Stuani, L.; Fuentes, M.; Talignani, C.; Rousseau, M.; Guegan, J.; Buscail, Y.; Dupre, P.; Michaud, H. A.; Rodier, G.; Bellvert, F.; Kulyk, H.; Ferraro, C.; Mathieu, H.; close, p.; Rapino, F.; Chaveroux, C.; Pirot, N.; Rubio, L.; Torro, A.; Sorg, T.; Ango, F.; Hirtz, C.; Compan, V.; Lebigot, E.; Legati, A.; Ghezzi, D.; Nguyen, L.; David, A.; Sardet, C.; Lacroix, M.; Lecam, L.
10.1101/2022.12.19.521032 — developmental biology — Posted on 2024-10-02
5228 Subgenual Anterior Cingulate Cortex Functional Connectivity Abnormalities in Depression: Insights from Brain Imaging Big Data and Precision-Guided Personalized Intervention via Transcranial Magnetic Stimulation
Chen, X.; Lu, B.; Wang, Y.-W.; Li, X.-Y.; Wang, Z.-H.; Li, H.-X.; Liao, Y.-F.; Blumberger, D. M.; Castellanos, F. X.; Cao, L.-P.; Chen, G.-M.; Chen, J.-S.; Chen, T.; Chen, T.-L.; Chen, Y.-R.; Cheng, Y.-Q.; Chu, Z.-S.; Cui, S.-X.; Cui, X.-L.; Deng, Z.-Y.; Gao, Q.-L.; Gong, Q.-Y.; Guo, W.-B.; He, C.-C.; Hu, Z.-J.-Y.; Huang, Q.; Ji, X.-L.; Jia, F.-N.; Kuang, L.; Li, B.-J.; Li, F.; Li, T.; Li, X.; Lian, T.; Liu, X.-Y.; Liu, Y.-S.; Liu, Z.-N.; Long, Y.-C.; Lu, J.-P.; Qiu, J.; Shan, X.-X.; Si, T.-M.; Sun, P.-F.; Wang, C.-Y.; Wang, H.-L.; Wang, X.; Wang, Y.; Wu, C.-N.; Wu, X.-P.; Wu, X.-R.; Wu, Y.-K.
10.1101/2023.03.09.531726 — neuroscience — Posted on 2024-10-02
5229 An active electronic, high-density epidural paddle array for chronic spinal cord neuromodulation
Parker, S. R.; Calvert, J. S.; Darie, R.; Jang, J.; Govindarajan, L. N.; Angelino, K.; Chitnis, G.; Iyassu, Y.; Shaaya, E.; Fridley, J. S.; Serre, T.; Borton, D. A.; McLaughlin, B. L.
10.1101/2024.05.29.596250 — bioengineering — Posted on 2024-10-02
5230 mTOR signaling promotes cytokine production in T cells through 3UTR-mediated translation control
Jurgens, A. P.; Zwijnen, J.; Van Alphen, F. P. J.; Bradaric, A.; Rooijers, K.; Hoogendijk, A. J.; Popovic, B.; Wolkers, M. C.
10.1101/2024.10.01.616022 — immunology — Posted on 2024-10-02
5231 LINE-1 ribonucleoprotein complexes bind DNA to enable nuclear entry during mitosis
Zernia, S.; Ettefa, F.; Sil, S.; Koeman, C.; Deplazes-Lauber, J.; Freitag, M.; Holt, L. J.; Stigler, J.
10.1101/2024.10.01.616040 — biophysics — Posted on 2024-10-02
5234 ClassiCOL: LC-MS/MS analysis for ancient species Classification via Collagen peptide ambiguation
Engels, I.; Burnett, A. C.; Dhaenens, M.; Daled, S.; Deforce, D.; De Groote, I.; Robert, P.; Pironneau, C.; Bouwmeester, R.; Fischer, V.; Abrams, G.; Otte, M.; Straus, L. G.; Di Modica, K.; Bray, F.; Van der Plaatsen, P.
10.1101/2024.10.01.616034 — bioinformatics — Posted on 2024-10-02
5235 Live-cell transcriptomics with engineered virus-like particles
Najia, M. A.; Borrajo, J.; Le, A.; Tsai, F.; Huang, J. Y.; Griffith, L. G.; Daley, G. Q.; Blainey, P. C.
10.1101/2024.10.01.616098 — bioengineering — Posted on 2024-10-02
5237 Predicting Inhibitors of OATP1B1 via Heterogeneous OATP-Ligand Interaction Graph Neural Network (HOLI-GNN)
Mardikoraem, M.; Eaves, J. N.; Belecciu, T.; Pascual, N. S.; Aljets, A.; Orlando, B. J.; Shapiro, E. M.; Woldring, D. R.
10.1101/2024.10.01.615464 — bioengineering — Posted on 2024-10-02
5242 A stable Netrin-1 fluorescent reporter chicken reveals cell-specific molecular signaturesduring optic fissure closure.
Chan, B. H. C.; Hardy, H.; Requena, T.; Findlay, A.; Ioannidis, J.; Meunier, D.; Toms, M.; Moosajee, M.; Raper, A.; McGrew, M.; Rainger, J.
10.1101/2024.10.01.616014 — developmental biology — Posted on 2024-10-02
5245 Verifying the concordance between motion corrected and conventional MPRAGE for pediatric morphometric analysis
Gal-Er, B.; Brackenier, Y.; Bonthrone, A. F.; Casella, C.; Price, A.; Arulkumaran, S.; Chew, A. T.; Nosarti, C.; Cleri, M.; Di Cio, P.; Egloff Collado, A.; Rutherford, M.; O'Muircheartaigh, J.; Tomi-Tricot, R.; Malik, S.; Cordero-Grande, L.; Hajnal, J. V.; Counsell, S. J.
10.1101/2024.10.01.616016 — neuroscience — Posted on 2024-10-02
5252 Mapping grey and white matter activity in the human brain with isotropic ADC-fMRI
Spencer, A. P. C.; Nguyen-Duc, J.; de Riedmatten, I.; Szczepankiewicz, F.; Jelescu, I. O.
10.1101/2024.10.01.615823 — neuroscience — Posted on 2024-10-02
5255 Generalizable gesture recognition usingmagnetomyography
Yun, R.; Csaky, R.; Dash, D.; Gerrard, I.; Kittle, E.; Taylor, D.; Soroushmojdehi, R.; Labanowski, D.; Deka, N.
10.1101/2024.09.30.615946 — neuroscience — Posted on 2024-10-02
5260 PHLOWER - Single cell trajectory analysis using Decomposition of the Hodge Laplacian
Cheng, M.; Jansen, J.; Reimer, K.; Nagai, J. S.; Li, Z.; Kiessling, P.; Grasshoff, M.; Kuppe, C.; Schaub, M.; Kramann, R.; Gesteira Costa Filho, I.
10.1101/2024.10.01.613179 — bioinformatics — Posted on 2024-10-02
5263 Coordinated control of genome-nuclear lamina interactions by Topoisomerase 2B and Lamin B receptor
Manzo, S. G.; van Schaik, T.; de Haas, M.; Breda, J.; Magnitov, M.; de Wit, E.; Gonzalez Manjon, A.; Medema, R. H.; Buckle, A. J.; Naughton, C.; Gilbert, N.; van Steensel, B.
10.1101/2024.10.01.616012 — genomics — Posted on 2024-10-02
5264 The Spc105-Kre28 complex promotes mitotic error correction by outer kinetochore recruitment of the Ipl1/Aurora B kinase
Dudziak, A.; Schmidt, J.; Hamm, F.; Tendulkar, S.; Jaenen, K.; Vetter, I. R.; Singh, S.; Fischboeck, J.; Herzog, F.; Westermann, S.
10.1101/2024.10.01.615642 — cell biology — Posted on 2024-10-02
5271 Building pangenome graphs
Garrison, E.; Guarracino, A.; Heumos, S.; Villani, F.; Bao, Z.; Tattini, L.; Hagmann, J.; Vorbrugg, S.; Marco-Sola, S.; Kubica, C.; Ashbrook, D. G.; Thorell, K.; Rusholme-Pilcher, R. L.; Liti, G.; Rudbeck, E.; Nahnsen, S.; Yang, Z.; Mwaniki, M. N.; Nobrega, F. L.; Wu, Y.; Chen, H.; de Ligt, J.; Sudmant, P. H.; Soranzo, N.; Colonna, V.; Williams, R. W.; Prins, P.
10.1101/2023.04.05.535718 — bioinformatics — Posted on 2024-10-02
5275 Dual Specificity Phosphatase 3 knockdown drives myeloid leukemia cells to differentiate into macrophages and polarize
Farias, J. O.; Pacheco, D. R. D. C. G.; Magalhaes, Y. T.; Russo, L. C.; Boell, V. K.; Hilares, D. J. F.; Forti, F. L.
10.1101/2024.09.30.615030 — immunology — Posted on 2024-10-02
5276 Heartbeat related activity in the anterior thalamus differs between phasic and tonic REM sleep periods
Simor, P.; Roka, Z. L.; Szalardy, O.; Jordan, Z.; Halasz, L.; Eross, L.; Fabo, D.; Bodizs, R.
10.1101/2024.09.30.615986 — neuroscience — Posted on 2024-10-02
5278 Loss of SARM1 protects against retinal ganglion cell degeneration in Autosomal Dominant Optic Atrophy
Ding, C.; Ndiaye, P. S.; Campbell, S. R.; Fry, M. Y.; Gong, J.; Wienbar, S. R.; Gibbs, W. S.; Morquette, P.; Chao, L. H.; Do, M. T. H.; Schwarz, T. L.
10.1101/2024.09.30.615936 — neuroscience — Posted on 2024-10-02
5279 Subendothelial Calcification Increases Surface Roughness and Promotes Lipid Deposition into the Arterial Wall
Kosciuszek, N. D.; Petrosian, D.; Voleti, N.; Dave, P.; Kelly, I.; Moussouros, D.; Davidov, J.; Mararenko, A.; Borges, K.; Nasruddin, S. A.; Padalkar, M.; Plummer, M.; Millan, J. L.; Carka, D.; Beatty, B. L.; Savinova, O. V.
10.1101/2024.09.30.615966 — physiology — Posted on 2024-10-02
5280 Sociality shapes mitochondrial adaptations supporting hypoxia tolerance
Rossi, A.; Ruwolt, M.; Kakouri, P.; Kosten, T.; Kunz, S.; Puchkov, D.; Reznick, J.; Omerbasic, D.; Aranda, D. M.; Carai, G.; Mastrobuoni, G.; Hart, D. W.; Carraro, M.; Tommasin, L.; Bennett, N. C.; Begay, V.; Faelber, K.; Daumke, O.; Bernardi, P.; Park, T.; Kempa, S.; Liu, F.; Lewin, G. R.
10.1101/2024.09.30.615914 — physiology — Posted on 2024-10-02
5281 Exploring New Horizons:A Novel Cdk5 Inhibitor Restoring Cognitive Function and Alleviating Type 2 Diabetes.
Paul, S.; Chandran, R.; Vijayan, D. K.; Bhardwaj, J.; Singh, P.; Poornima Shetty, P.; Cheruku, S.; Meleveetil, S.; BK, B.
10.1101/2024.09.30.615976 — pharmacology and toxicology — Posted on 2024-10-02
5283 Mutant IDH uncouples p53 from target gene regulation to disable tumor suppression
Martin, C. P.; Sullivan, W. B.; Brinkman, J.; Scoville, D. M.; Yashinskie, J. J.; Tian, S.; Mezzadra, R. E.; Ho, Y.-J.; Koche, R. P.; Baslan, T.; Raab, J.; Corcoran, D.; Finley, L. W. S.; Lowe, S. W.; Morris, J. P.
10.1101/2024.09.30.615916 — cancer biology — Posted on 2024-10-02
5286 Sporadic distribution of a new archaeal genetic code with all TAG codons as pyrrolysine
Kivenson, V.; Peters, S. L.; Borrel, G.; Kivenson, A.; Roe, L. T.; Hamlish, N. X.; Fadhlaoui, K.; Schepartz, A.; Gribaldo, S.; Hettich, R.; Banfield, J.
10.1101/2024.09.30.615893 — genomics — Posted on 2024-10-02
5289 A sustainable and bee-pollinated coffee to start your day
Alves, D. A.; Ramos, J. D.; dos Santos, C. F.; Oliveira, D. M.; Almeida-Dias, J. M. V.; Santos, G. S.; Kaminsk, T. S. d. O.; Cione, A. P.; Quenzer, F. C. L.; Campbell, A. J.; Berretta, A. A.; Sousa, G. J. G.; Pereira, A. M.; Thompson, H.; Vasconcelos, N. B. d. T.; Cruz, R.; de Queiroz, A. C. M.; Bento, J. M. S.; Menezes, C.
10.1101/2024.09.30.615918 — ecology — Posted on 2024-10-02
5292 Circulatory proteins shape microglia state and boost phagocytosis
Lu, N.; Moran-Losada, P.; Hahn, O.; Saksena, A.; Tapp, E.; Chadarevian, J. P.; Dong, W.; Shi, S. M.; Shuken, S. R.; Guldner, I.; Zeng, W.; To, N.-S.; Wong, P. S.; Hasselmann, J.; Davtyan, H.; Sun, J.; Li, L.; Luo, J.; Yang, A. C.; Li, Q.; Cheung, T. H.; Abu-Remaileh, M.; Blurton-Jones, M.; Wyss-Coray, T.
10.1101/2024.09.30.615861 — neuroscience — Posted on 2024-10-02
5293 Autophagic enhancer rescues Tau accumulation in a stem cell model of frontotemporal dementia
Mirfakhar, F.; Marsh, J.; Minaya, M.; Pak, S.; Silverman, G.; Perlmutter, D.; Macauley, S.; Karch, C.
10.1101/2024.09.30.615921 — neuroscience — Posted on 2024-10-02
5294 Age dependency of neurometabolite T1 relaxation times
Murali-Manohar, S.; Zoellner, H. J.; Hupfeld, K. E.; Song, Y.; Carter, E. E.; Yedavalli, V.; Hui, S. C. N.; Simicic, D.; Gudmundson, A. T.; Simegn, G. L.; Davies-Jenkins, C. W.; Oeltzschner, G.; Porges, E. C.; Edden, R. A. E.
10.1101/2024.09.30.615917 — neuroscience — Posted on 2024-10-02
5297 Increased CPT1a expression is a critical cardioprotective response to pathological stress that suppresses gene programs for remodeling and enables rescue by gene transfer
Carley, A. N.; Maurya, S. K.; Maurya, C. K.; Wang, Y.; Webb, A.; Challa, A. A.; Zhang, Z.; Zhu, H.; Heydemann, A.; Bedi, K.; Kyriakopoulos, C. P.; Selzman, C. H.; Drakos, S. G.; Margulies, K. B.; Lewandowski, E. D.
10.1101/2024.09.30.615965 — physiology — Posted on 2024-10-02
5299 Multiplexed functional analysis of TAP2 variants in regulating MHC-I cell surface abundance reveals overexpression of PLK1 downregulates antigen presentation.
Nagy, G.; Presley, R.; Jeon, H.; Moreira, L.; Dhar, S.; Tull, O.; Soysal, B.; Yadati, A. S.; Cook, K. D.; Schnell, L. E.; Gupta, A.; Banerjee, T.; Chung, D.; Tsichlis, P. N.; Parvin, J. D.
10.1101/2024.09.30.615919 — cancer biology — Posted on 2024-10-02
5301 Deciphering shared molecular dysregulation across Parkinson's disease variants using a multi-modal network-based data integration and analysis
Zagare, A.; Balaur, I.; Rougny, A.; Saraiva, C.; Gobin, M.; Monzel, A. S.; Ghosh, S.; Satagopam, V. P.; Schwamborn, J. C.
10.1101/2024.09.30.615801 — systems biology — Posted on 2024-10-02
5303 Neuronally differentiated endothelial cell subtype regulates organ blood flow and immune balance
Gyarmati, G.; Rust, R.; Calderon, A. B.; Izuhara, A.; Trogen, G.; Deepak, S.; Chen, Y.; Ruffins, S. W.; Junge, J. A.; Zlokovic, B. V.; Fraser, S. E.; Peti-Peterdi, J.
10.1101/2024.09.30.615824 — physiology — Posted on 2024-10-02
5305 Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma
Popova, L. V.; Garfinkle, E. A. R.; Chopyk, D. M.; Navarro, J. B.; Rivaldi, A.; Shu, Y.; Lomonosova, E.; Phay, J. E.; Miller, B. S.; Sattuwar, S.; Mardis, E. R.; Miller, K. E.; Dedhia, P. H.
10.1101/2024.09.30.615695 — cancer biology — Posted on 2024-10-02
5306 Phage display enables machine learning discovery of cancer antigen specific TCRs
Croce, G.; Lani, R.; Tardivon, D.; Bobisse, S.; de Tiani, M.; Bragina, M.; Perez, M. A.; Schmidt, J.; Guillame, P.; Zoete, V.; Harari, A.; Rufer, N.; Hebeisen, M.; Dunn, S.; Gfeller, D.
10.1101/2024.06.27.600973 — bioinformatics — Posted on 2024-10-02
5307 Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and Ca2+
Tsai, S.-J.; Gong, Y.; Dabbs, A.; Zahra, F.; Xu, J.; Geske, A.; Caterina, M. J.; Gould, S. J.
10.1101/2024.09.30.615856 — bioengineering — Posted on 2024-10-02
5308 Sustained exposure to multivalent antigen-decorated nanoparticles generates broad anti-coronavirus responses
Baillet, J.; Klich, J. H.; Ou, B. S.; Meany, E. L.; Yan, J.; Bruun, T. U. J.; Utz, A.; Jons, C. K.; Lecommandoux, S.; Appel, E. A.
10.1101/2024.10.01.616060 — bioengineering — Posted on 2024-10-02
5310 Alternate RNA decoding results in stable and abundant proteins in mammals
Tsour, S.; Machne, R.; Leduc, A.; Widmer, S.; Guez, J.; Karczewski, K.; Slavov, N.
10.1101/2024.08.26.609665 — genomics — Posted on 2024-10-02
5311 rDNA copy number variation in yeast alters response to environmental conditions
Thornton, K.; Kwan, E.; Bubb, K. L.; Paleologu, L.; Raghuraman, M. K.; Brewer, B. J.; Cuperus, J. T.; Queitsch, C.
10.1101/2024.09.30.615902 — genetics — Posted on 2024-10-02
5313 Soil biodiversity in the Atacama Desert shows distinct patterns at different diversity levels
Villegas, L.; Pettrich, L.; Acevedo-Trejos, E.; Suwanngam, A.; Wassey, N.; Allende, M. L.; Stoll, A.; Holovachov, O.; Waldvogel, A.-M.; Schiffer, P. H.
10.1101/2024.09.30.615889 — ecology — Posted on 2024-10-02
5314 RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation
Ganguli, S.; Gupta, D.; Ramaswamy, R.; Kodumuri, R. V.; Krishnan, A. G.; Tandel, D.; David, D. T.; Bunk, S.; Chavali, S.; Harshan, K. H.; Chavali, P. L.
10.1101/2024.09.29.615653 — cell biology — Posted on 2024-10-02
5315 SIRT4 enhances the cytotoxicity of NK cells toward hepatic stellate cells and reverses liver fibrosis via AMPKα/P-p53/NKG2DL pathway
Zhang, F.; Chen, H.; Da, B.; Cai, Z.; Fang, R.; Zhang, H.; Xie, X.; Zhao, S.; Zhang, M.; Wang, L.; Xu, B.; Zhuge, Y.
10.1101/2024.09.30.615768 — cell biology — Posted on 2024-10-02
5316 B cell c-Maf signaling promotes tumor progression in animal models of pancreatic cancer and melanoma
Zhong, Q.; Hao, H.; Li, S.; Ning, Y.; Li, H.; Hu, X.; McMasters, K. M.; Yan, J.; DING, C.
10.1101/2024.09.30.615831 — immunology — Posted on 2024-10-02
5318 Brain-wide connectivity and novelty response of the dorsal endopiriform nucleus in mice
Manjila, S. B.; Son, S.; Kline, H.; Betty, R.; Wu, Y.-t.; Pi, H.-J.; Parmaksiz, D.; Shin, D.; Liwang, J. K.; Kronman, F. N.; Paul, A.; Kim, Y.
10.1101/2024.09.30.615899 — neuroscience — Posted on 2024-10-02
5320 Expanding the toolkit for ploidy manipulation in Chlamydomonas reinhardtii
Van de Vloet, A.; Prost-Boxoen, L.; Bafort, Q.; Paing, Y. T.; Casteleyn, G.; Jomat, L.; Lemaire, S.; De Clerck, O.; Van de Peer, Y.
10.1101/2024.10.01.616035 — synthetic biology — Posted on 2024-10-02
5321 Cell extract-based in vitro DNA replication enables sustainable cell-free gene expression
Zheng, X.; Gao, W.; Liu, W.-Q.; Zhang, Y.; Lu, Y.; Huang, S.; Ji, X.; Liu, Y.; Ling, S.; Li, J.
10.1101/2024.10.01.616023 — synthetic biology — Posted on 2024-10-02
5322 Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling
Sudupe, L.; Muinos-Lopez, E.; Lopez-Perez, A. R.; Vilas-Zornoza, A.; Sarvide, S.; Ripalda-Cemborain, P.; Aguirre-Ruiz, P.; San Martin-Uriz, P.; Larrayoz, M.; Alvarez-Gigli, L.; Abengozar-Muela, M.; Cenzano, I.; Cocera, M.; Ruiz, J.; Sancho Gonzalez, I.; Bantan, A.; Kurowska, A.; Ye, J.; Newton, P. T.; Paiva, B.; Rodriguez-Madoz, J. R.; Lagani, V.; Tegner, J.; Saez, B.; Martinez-Climent, J. A.; Calvo Arnedo, I.; Gomez-Cabrero, D.; Prosper, F.
10.1101/2024.07.03.601833 — cancer biology — Posted on 2024-10-02
5323 A CD24+CD271+ Melanoma Cancer Stem Cell Possesses Hybrid Characteristics of its Single Marker Counterparts and Promotes Invasion and Therapeutic Resistance
Knowles, O.; Doldan, P.; Hillier-Richardson, I.; Lunt, S.; Youssef, G.; Gammon, L.; Mackenzie, I. C.; Philpott, M. P.; Rizvi, H.; Bergamaschi, D.; Harwood, C. A.; Biddle, A.
10.1101/2023.06.07.544036 — cancer biology — Posted on 2024-10-02
5324 Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis
Salamero-Boix, A.; Schulz, M.; Anthes, J.; Mayer, J.; Moeckl, A.; Tsoukala, I.; Menger, D.; Mosa, M.; Hetzer, J.; Macas, J.; Hehlgans, S.; Schuck, J.; Roller, B.; Reiss, Y.; Hochart, G.; Bonnel, D.; Medyouf, H.; Rodriguez, M. B.; Broggini, T.; Czabanka, M.; Plate, K. H.; Heikenwaelder, M.; Roedel, F.; Harter, P. N.; Imkeller, K.; Sevenich, L.
10.1101/2024.09.30.615883 — cancer biology — Posted on 2024-10-02
5326 Escape problem of magnetotactic bacteria - physiological magnetic field strengths help magnetotactic bacteria navigate in simulated sediments
Codutti, A.; Charsooghi, M.; Marx, K.; Cerda-Donate, E.; Munoz, O.; Zaslansky, P.; Telezki, V.; Robinson, T.; Faivre, D.; Klumpp, S.
10.1101/2023.12.08.570788 — biophysics — Posted on 2024-10-02
5328 Population genomics uncover loci for trait improvement in the indigenous African cereal tef (Eragrostis tef)
Jones, M. R. W.; Kebede, W.; Teshome, A.; Girija, A.; Teshome, A.; Kebede, D. G.; Brown, J. K. M.; Quiroz-Chavez, J.; Jones, C. S.; Wulff, B. B. H.; Assefa, K.; Tadele, Z.; Mur, L. A. J.; Chanyalew, S.; Uauy, C.; Shorinola, O.
10.1101/2024.09.30.615331 — genomics — Posted on 2024-10-02
5330 Interrogating the plasma proteome of repetitive head impact exposure and chronic traumatic encephalopathy
Saloner, R.; Casaletto, K. B.; Rayaprolu, S.; Chakrabarty, P.; Abisambra, J. F.; Spina, S.; Grinberg, L. T.; Seeley, W. W.; Miller, B. L.; Kramer, J. H.; Rabinovici, G. D.; Asken, B. M.
10.1101/2024.10.01.616097 — molecular biology — Posted on 2024-10-02
5331 Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles
Rosenblum, Y.; Jafarzadeh Esfahani, M.; Adelhöfer, N.; Zerr, P.; Furrer, M.; Huber, R.; Roest, F. F.; Steiger, A.; Zeising, M.; Horvath, C. G.; Schneider, B.; Bodizs, R.; Dresler, M.
10.1101/2023.07.04.547323 — neuroscience — Posted on 2024-10-02
5332 Effort Drives Saccade Selection
Koevoet, D.; Van Zantwijk, L.; Naber, M.; Mathot, S.; Van der Stigchel, S.; Strauch, C.
10.1101/2024.02.06.579052 — neuroscience — Posted on 2024-10-02
5335 Identification of Long Non-coding RNA Candidate Disease Genes Associated with Clinically Reported CNVs in Congenital Heart Disease
Penaloza, J. S.; CCVM Consortium, ; Moreland, B.; Gaither, J. B.; Landis, B. J.; Ware, S. M.; McBride, K. L.; White, P.
10.1101/2024.09.30.615967 — genomics — Posted on 2024-10-02
5336 Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs
Bizzotto, S.; Stronge, E. A.; Talukdar, M.; Hu, Q.; Zhou, Z.; Huang, A. Y.; Chhouk, B. H.; D'Gama, A. M.; Yang, E.; Green, T. E.; Reutens, D. C.; Mullen, S. A.; Hildebrand, M. S.; Buono, R. J.; Poduri, A. H.; Khoshkhoo, S.; Walsh, C. A.
10.1101/2024.10.01.615793 — genetics — Posted on 2024-10-02
5337 Effect heterogeneity reveals complex pleiotropic effects of rare coding variants
Lu, W.; Chen, S.; Posthuma, D.; Neale, B.; O'Connor, L. J.; Karczewski, K.
10.1101/2024.10.01.614806 — genetics — Posted on 2024-10-02
5340 Measuring age-dependent viscoelastic properties of organelles, cells and organisms via Time-Shared Optical TweezerMicrorheology
Catala-Castro, F.; Ortiz-Vasquez, S.; Martinez-Fernandez, C.; Pezzano, F.; Garcia-Cabau, C.; Fernandez-Campo, M.; Sanfeliu-Cerdan, N.; Jimenez-Delgado, S.; Salvatella, X.; Ruprecht, V.; Frigeri, P. A.; Krieg, M.
10.1101/2023.10.17.562595 — biophysics — Posted on 2024-10-02
5341 AptaDiff: de novo design and optimization of aptamers based on diffusion models
Wang, Z.; Liu, Z.; Zhang, W.; Li, Y.; Feng, Y.; Lv, S.; Diao, H.; Luo, Z.; Yan, P.; He, M.; Li, X.
10.1101/2023.11.25.568693 — bioinformatics — Posted on 2024-10-02
5345 Long range mutual activation establishes Rho and Rac polarity during cell migration
De Belly, H.; Gallen, A. F.; Strickland, E.; Estrada, D. C.; Zager, P. J.; Burkhardt, J. K.; Turlier, H.; Weiner, O.
10.1101/2024.10.01.616161 — cell biology — Posted on 2024-10-02
5347 High-Complexity Barcoded Rabies Virus for Scalable Circuit Mapping Using Single-Cell and Single-Nucleus Sequencing
Shin, D.; Urbanek, M. E.; Larson, H. H.; Moussa, A. J.; Lee, K. Y.; Baker, D. L.; Standen-Bloom, E.; Ramachandran, S.; Bogdanoff, D.; Cadwell, C. R.; Nowakowski, T. J.
10.1101/2024.10.01.616167 — neuroscience — Posted on 2024-10-02
5348 Recurrent circuits encode visual center-surround computations in the mouse superior colliculus
Cui, P.; Song, K.; Mariatos Metaxas, D.; Isla, A. G.; Femenia, T.; Lazaridis, I.; Meletis, K.; Kumar, A.; Kardamakis, A. A.
10.1101/2023.09.03.556096 — neuroscience — Posted on 2024-10-02
5350 Real-time prediction of drug-induced proarrhythmic risk with sex-specific cardiac emulators
Dominguez-Gomez, P.; Zingaro, A.; Baldo-Canut, L.; Balzotti, C.; Darpo, B.; Morton, C.; Vazquez, M.; Aguado-Sierra, J.
10.1101/2024.09.30.615798 — pharmacology and toxicology — Posted on 2024-10-02
5351 The host genotype actively shapes its microbiome across generations
Benga, L.; Rehm, A.; Gougoula, C.; Westhoff, P.; Wachtmeister, T.; Benten, W. P. M.; Engelhardt, E.; Weber, A. P. M.; Koehrer, K.; Sager, M.; Janssen, S.
10.1101/2024.03.14.584950 — ecology — Posted on 2024-10-02
5352 A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology
Kesapragada, M.; Sun, Y.-H.; Zhu, K.; Recendez, C.; Fregoso, D.; Yang, H.-y.; Rolandi, M.; Isseroff, R. R.; Zhao, M.; Gomez, M.
10.1101/2022.11.29.518400 — cell biology — Posted on 2024-10-02
5354 12-Lipoxygenase Inhibition Suppresses Islet Immune and Inflammatory Responses and Delays Autoimmune Diabetes in Human Gene Replacement Mice
Nargis, T.; Muralidharan, C.; Enriquez, J. R.; Wang, J. E.; Kaylan, K.; Chakraborty, A.; Pratuagntham, S.; Figatner, K.; Nelson, J. B.; May, S. C.; Nadler, J. L.; Boxer, M. B.; Maloney, D. J.; Tersey, S. A.; Mirmira, R. G.
10.1101/2024.07.28.604986 — molecular biology — Posted on 2024-10-02
5355 An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells
Blancke Soares, A.; Staecker, J.; Schwald, S.; Hoijmakers, W. A. M.; Metwally, N. G.; Cronshagen, J.; Schoeler, H.; Flemming, S.; Hoehn, K.; Froehlke, U.; Mesen-Ramirez, P.; Bergmann, B.; Khosh-Naucke, M.; Bruchhaus, I.; Bartfai, R.; Spielmann, T.
10.1101/2021.12.03.471078 — microbiology — Posted on 2024-10-02
5356 Violated predictions enhance the representational fidelity of visual features in perception
Rideaux, R.; Dang, P.; Jackel-David, L.; Buhmann, Z.; Rangelov, D.; Mattingley, J. B.
10.1101/2024.03.27.587109 — neuroscience — Posted on 2024-10-02
5357 A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex
Hes, C.; Tomlinson, A. J.; Michielsen, L.; Murdoch, H. J.; Soltani, F.; Kokoeva, M.; Sabatini, P. V.
10.1101/2024.09.19.613879 — neuroscience — Posted on 2024-10-02
5364 A newly developed whole genome sequencing protocol enables early tracking of Enterovirus D68 molecular evolution.
Giardina, F. A.; Romano, G.; Ferrari, G.; Pellegrinelli, L.; Seiti, A.; Galli, C.; Pariani, E.; Piralla, A.; Baldanti, F.
10.1101/2024.09.30.615419 — microbiology — Posted on 2024-10-02
5365 Spatial and Spectral Changes in Cortical Surface Potentials during Pinching versus Thumb and Index Finger Flexion
Kerezoudis, P.; Jensen, M.; Huang, H.; Ojemann, J.; Klassen, B. T.; Ince, N. F.; Hermes, D.; Miller, K. J.
10.1101/2024.09.30.615538 — neuroscience — Posted on 2024-10-02
5367 Controllability and cause in human collaboration
Spiering, L.; Trier, H.; O'Reilly, J.; Kolling, N.; Wittmann, M.; Rushworth, M.; Scholl, J.
10.1101/2024.10.01.615833 — neuroscience — Posted on 2024-10-02
5371 Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing
Shi, H.; Al-Sayyad, N.; Wasko, K.; Trinidad, M. I.; Doherty, E. E.; Vohra, K.; Boger, R. S.; Colognori, D.; Cofsky, J. C.; Skopintsev, P.; Bryant, Z.; Doudna, J. A.
10.1101/2024.10.01.616117 — biophysics — Posted on 2024-10-02
5372 Host specialization defines the emergence of new fungal plant pathogen populations
C. Fagundes, W.; Hansen, R.; Rojas Barrera, I. C.; Caliebe, F.; Feurtey, A.; Haueisen, J.; Salimi, F.; Alizadeh, A.; H. Stukenbrock, E.
10.1101/2024.09.30.615799 — evolutionary biology — Posted on 2024-10-02
5373 Epigenome profiling identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis
Ditzer, N.; Senoglu, E.; Schutze, T. M.; Nikolaidi, A.; Kolodziejczyk, A.; Sameith, K.; Dietz, S.; Derihaci, R. P.; Birdir, C.; Eugster, A.; Karl, M. O.; Dahl, A.; Wimberger, P.; Baenke, F.; Peitzsch, C.; Albert, M.
10.1101/2024.10.01.616076 — developmental biology — Posted on 2024-10-02
5374 A molecular basis for plant SCAR/WAVE functional divergence
Brumm, S.; Gavrin, A.; MacLeod, M.; Chesneau, G.; Uslaender, A.; Schornack, S.
10.1101/2024.10.01.616141 — plant biology — Posted on 2024-10-01
5377 Tumor Priming by Ultrasound Mechanogenetics for with SynNotch CAR T Therapy
Yoon, C. W.; Song, C.; Nguyen, D. N. M.; Zhu, L.; Ho, P.; Huang, Z.; Lu, G.; Zamat, A.; Lewis, A.; Chen, R.; Zeng, Y.; Lee, N. S.; Jamieson, C.; Shung, K. K.; Wang, Y.
10.1101/2024.10.01.615989 — synthetic biology — Posted on 2024-10-01
5379 De novo design of proteins that bind naphthalenediimides, powerful photooxidants with tunable photophysical properties
Mann, S. I.; Lin, Z.; Tan, S. K.; Zhu, J.; Widel, Z. X.; Bakanas, I.; Mansergh, J. P.; Liu, R.; Kelly, M. J.; Wu, Y.; Wells, J. A.; Therien, M. J.; DeGrado, W. A.
10.1101/2024.09.30.615927 — biophysics — Posted on 2024-10-01
5381 Two-dimensional condensates of HRS drive the assembly of flat clathrin lattices on endosomes
Hakala, M.; Moparthi, S. B.; Ganeva, I.; Bernat-Silvestre, C.; Espadas, J.; Kukulski, W.; Vassilopoulos, S.; Kaksonen, M.; Roux, A.
10.1101/2024.10.01.616068 — biochemistry — Posted on 2024-10-01
5382 In silico modelling and characterization of Epstein Barr virus LMP1 protein
Abdul Salam, D. S.; Gunasinghe, K. J.; Hwang, S. S.; Ginjom, I. R.; CHEE, X.; Rahman, T.
10.1101/2024.09.30.615964 — biochemistry — Posted on 2024-10-01
5383 Structure of the CABIT2 domain of THEMIS reveals a novel protein fold with an inserted SH3-like domain
Beyett, T. S.; Yurtsever, Z.; Schaeffner, I. K.; Rana, J. K.; Robbie, L. K.; Ortiz-Salazar, D.; Eck, M. J.
10.1101/2024.10.01.616165 — biochemistry — Posted on 2024-10-01
5385 The role of cytochrome c in mitochondrial metabolism of human oocytes
Surmacki, J. M.; Abramczyk, H.; Sobkiewicz, B.; Walczak Jedrzejowska, R.; Slowikowska Hilczer, J.; Marchlewska, K.
10.1101/2024.10.01.616010 — cell biology — Posted on 2024-10-01
5387 Multi-omics analysis reveals the mechanism of BnC07MYB3a is involved in seed coat color in Brassica napus L.
Hu, R.; Zhang, M.; Shen, S.; Liu, H.; Gao, L.; Tian, M.; Liu, Y.; Wan, H.; Zhao, H.; Yin, N.; Du, H.; Liu, L.; Lu, K.; Li, J.; Qu, C.
10.1101/2024.09.30.615900 — molecular biology — Posted on 2024-10-01
5388 A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity
Beshr, G.; Sikandar, A.; Glaeser, J.; Fares, M.; Sommer, R.; Wagner, S.; Koehnke, J.; Titz, A.
10.1101/2024.10.01.616118 — microbiology — Posted on 2024-10-01
5390 The c-di-GMP effector FleQ controls alginate production by repressing transcription of the algD gene in Azotobacter vinelandii
BARRIOS-RAFAEL, V. V.; AHUMADA-MANUEL, C. L.; ORGAZ-HIDALGO, S.; NAVA-GALEANA, J.; GUZMAN, J.; NORENO, S.; BUSTAMANTE, V. H.; Nunez, C.
10.1101/2024.09.30.615961 — microbiology — Posted on 2024-10-01
5391 Amelioration of Oxidative Stress in Sodium Fluoride-administered Wistar Rats by Tamarindus indica Fruit Pulp Ethanolic Extract
Usman, L. A.; Ajani, E. O.; Ishiaku, M. A.; Bankole, T. A.; Ibrahim, R. B.; Saka, D. K.; Abdulameed, H. T.; Aladodo, R. A.
10.1101/2024.10.01.615996 — biochemistry — Posted on 2024-10-01
5393 A molecular representation system with a common reference frame for natural products pathway discovery and structural diversity tasks.
Babineau, N.; Nguyen, L. T. D.; Mathieu, D.; McCue, C.; Schlecht, N.; Abrahamson, T.; Hamberger, B.; Busta, L.
10.1101/2024.10.01.616173 — biochemistry — Posted on 2024-10-01
5394 Evolutionary origins and innovations sculpting the mammalian PRPS enzyme complex
Karki, B.; Macmillan, A. C.; Vicente-Munoz, S.; Greis, K. D.; Romick, L. E.; Cunningham, J. T.
10.1101/2024.10.01.616059 — biochemistry — Posted on 2024-10-01
5395 Computing the Human Interactome
Zhang, J.; Humphreys, I. R.; Pei, J.; Kim, J.; Choi, C.; Yuan, R.; Durham, J.; Liu, S.; Choi, H.-J.; Baek, M.; Baker, D.; Cong, Q.
10.1101/2024.10.01.615885 — biochemistry — Posted on 2024-10-01
5396 Development of potent and selective CK1α Molecular Glue Degraders
Geng, Q.; Jiang, Z.; Byun, W. S.; Donovan, K. A.; Zhuang, Z.; Jiang, F.; Jones, H. M.; Razumkov, H.; Tang, M. T.; Sarott, R. C.; Fischer, E. S.; Corsello, S. M.; Hinshaw, S. M.; Gray, N. S.
10.1101/2024.10.01.616159 — biochemistry — Posted on 2024-10-01
5397 Longhorn Beetles form Structural Colour Using Calcium Phosphate Biominerals
Chang, Y.; Tseng, H.-H.; Masahiko, T.; Pohl, D.; Rellinghaus, B.; Bertinetti, L.; Politi, Y.
10.1101/2024.10.01.616160 — molecular biology — Posted on 2024-10-01
5400 Trafficking and translation of mRNA in osteocyte dendrites
Mazur, C. M.; Kotsalidis, P. E.; Andrade, C. D. C.; Wu, M.; Wang, X.; Taliaferro, M.; Wein, M. N.
10.1101/2024.10.01.616162 — molecular biology — Posted on 2024-10-01
5403 Teicoplanin attenuates RNA virus infection in vitro
Espano, E.; Kim, J.; Park, S. O.; Padasas, B. T.; Kim, S.-H.; Son, J.-H.; Oh, J.; Woo, E.-E.; Lee, Y.-R.; Hwang, S. Y.; Eo, S. K.; Kim, J.-K.
10.1101/2024.09.29.615295 — microbiology — Posted on 2024-10-01
5404 Group B streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model
Ravishankar, S.; Tuohey, S. M.; Ramos, N. O.; Uchiyama, S.; Hayes, M. I.; Nizet, V.; Madigan, C. A.
10.1101/2024.10.01.616123 — microbiology — Posted on 2024-10-01
5405 PfPPM2 signalling regulates asexual division and sexual conversion of human malaria parasite Plasmodium falciparum
Rawat, A.; Antil, N.; No last name, M.; Deshmukh, B.; Rai, A. B.; Kumar, N.; T S, K. P.; Karmodiya, K.; Sharma, P.
10.1101/2024.10.01.615984 — microbiology — Posted on 2024-10-01
5406 In vitro discovery of a therapeutic lead for HFMD from a library screen of rocaglates/aglains
Oo, A.; Borge, A.; Lee, R. C. H.; Salim, C. K.; Wang, W.; Ricca, M.; Fong, D. Y.; Alonso, S.; Brown, L. E.; Porco, J. A.; Chu, J. J. H.
10.1101/2024.09.30.615979 — microbiology — Posted on 2024-10-01
5407 Characterization of vaginal microbiomes in clinician-collected bacterial vaginosis diagnosed samples
Brochu, H. N.; Zhang, Q.; Song, K.; Wang, L.; Deare, E. A.; Williams, J. D.; Icenhour, C. R.; Iyer, L. K.
10.1101/2024.10.01.616135 — microbiology — Posted on 2024-10-01
5412 Cxcl10 is required for survival during SARS-CoV-2 infection in mice
Majumdar, S.; Weaver, J. D.; Pontejo, S. M.; Mahnaz, M.; Lu, X.; Gao, J.-L.; Holmes, G.; Johnson, R.; Zhang, H.; Kelsall, B. L.; Farber, J. M.; Alves, D. A.; Murphy, P. M.
10.1101/2024.09.30.613319 — immunology — Posted on 2024-10-01
5413 Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording
McDiarmid, T. A.; Taylor, M. L.; Chen, W.; Chardon, F. M.; Choi, J.; Liao, H.; Li, X.; Kim, H.; Lalanne, J.-B.; Li, T.; Nathans, J. F.; Martin, B. K.; Knuth, J.; Coradini, A. L. V.; Gray, J. M.; Pinglay, S.; Shendure, J.
10.1101/2024.09.30.615957 — synthetic biology — Posted on 2024-10-01
5414 Design of nanobody targeting SARS-CoV-2 spike glycoprotein using CDR-grafting assisted by molecular simulation and machine learning
Ferraz, M. V. F.; Adan, W. C. S.; Lima, T. E.; Santos, A. J. C.; de Paula, S. O.; Dhalia, R.; Wallau, G. L.; Wade, R. C.; Viana, I. F. T.; Lins, R. D.
10.1101/2024.09.30.615772 — biophysics — Posted on 2024-10-01
5417 scGNN+: Adapting ChatGPT for Seamless Tutorial and Code Optimization
Jiang, Y.; Wang, S.; Feng, S.; Wang, C.; Wu, W.; Huang, X.; Ma, Q.; Wang, J.; Ma, A.
10.1101/2024.09.30.615735 — bioinformatics — Posted on 2024-10-01
5418 Experience in developing the human genome standard E701
Vasiliadis, I.; Belova, V.; Shmitko, A.; Kuznetsova, A.; Samitova, A.; Suchalko, O.; Goltsov, A.; Shatalov, P.; Shegai, P.; Melkova, O.; Kulyabina, T.; Kulyabina, E.; Rebrikov, D.; Korostin, D.
10.1101/2024.09.30.615836 — genomics — Posted on 2024-10-01
5420 Do pollinators play a role in shaping the essential amino acids found in nectar?
Parkinson, R. H.; Power, E. F.; Walter, K.; McDermott-Roberts, A. E.; Pattrick, J. G.; Wright, G. A.
10.1101/2024.09.30.615756 — ecology — Posted on 2024-10-01
5427 Conservation of an immune homeostasis module in land plants
Dou, R.; El Mahboubi, K.; Tanney, C. A. S.; Chu, J.; Bredow, M.; Gallo, M. C. R.; Lauressergues, D.; Keller, J.; Miguel, V. N.; DeFalco, T. A.; Uhrig, R. G.; Zipfel, C.; Delaux, P.-M.; Monaghan, J.
10.1101/2024.10.01.616128 — plant biology — Posted on 2024-10-01
5428 Acid excretion is impaired in calcium oxalate stone formers
Silva, P. H. I.; Dhayat, N. A.; Fuster, D. G.; Seeger, H.; Ritter, A.; Ernandez, T.; Buchkremer, F.; Roth, B.; Bonny, O.; Rubio-Aliaga, I.; Wagner, C. A.
10.1101/2024.09.30.615797 — physiology — Posted on 2024-10-01
5429 Real-time prediction of drug-induced proarrhythmic risk with sex-specific cardiac emulators
Dominguez-Gomez, P.; Zingaro, A.; Baldo-Canut, L.; Darpo, B.; Morton, C.; Vazquez, M.; Aguado-Sierra, J.
10.1101/2024.09.30.615798 — pharmacology and toxicology — Posted on 2024-10-01
5430 Identification and characterization of tertiary lymphoid structures in brain metastases
Mughal, S. S.; Reiss, Y.; Felsberg, J.; Meyer, L.; Macas, J.; Schlue, S.; Starzetz, T.; Koehrer, K.; Fehm, T.; Mueller, V.; Lamszus, K.; Schadendorf, D.; Helfrich, I.; Wikman, H.; Berghoff, A.; Brors, B.; Plate, K. H.; Reifenberger, G.
10.1101/2024.09.30.614674 — cancer biology — Posted on 2024-10-01
5431 Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax
Jones, D.; Woods, E.; Li, Z.; Schaller, K. L.; Hoffmeyer, E.; Kooiman, B.; Fernandez, J.; Wharton, T.; Tufa, D.; Hall, S. C.; Trahan, G.; Maloney, K.; Pacenta, H.; Sullivan, K.; Espinosa, J.; Roede, J. R.; Marentette, J.; Stevens, B.; Inguva, A.; Stephenson, D.; Reisz, J. A.; D'Alessandro, A.; Jordan, C. T.; Yang, J. J.; Verneris, M. R.
10.1101/2024.09.30.615872 — cancer biology — Posted on 2024-10-01
5432 Transient protein structure guides surface diffusion pathways for electron transport in membrane supercomplexes
Chan, C. K.; Nguyen, J.; Hryc, C. F.; Gupta, C.; Redding, K.; Dowhan, W.; Baker, M. L.; Perez, A.; Mileykovskaya, E.; Singharoy, A.
10.1101/2024.09.30.615558 — biophysics — Posted on 2024-10-01
5433 BindCraft: one-shot design of functional protein binders
Pacesa, M.; Nickel, L.; Schmidt, J.; Pyatova, E.; Schellhaas, C.; Kissling, L.; Alcaraz-Serna, A.; Cho, Y.; Ghamary, K. H.; Vinue, L.; Yachnin, B. J.; Wollacott, A. M.; Buckley, S.; Georgeon, S.; Goverde, C. A.; Hatzopoulos, G. N.; Gonczy, P.; Muller, Y. D.; Schwank, G.; Ovchinnikov, S.; Correia, B. E.
10.1101/2024.09.30.615802 — bioinformatics — Posted on 2024-10-01
5434 Preserving Full Spectrum Information in ImagingMass Spectrometry Data Reduction
Moens, R. A. R.; Migas, L. G.; Van Ardenne, J. M.; Skaar, E. P.; Spraggins, J. M.; Van de Plas, R.
10.1101/2024.09.30.614425 — bioinformatics — Posted on 2024-10-01
5435 Isobaric labeling update in MaxQuant
Ferretti, D.; Kyriakidou, P.; Xiao, J.; Urazbakhtin, S.; De Nart, C.; Cox, J.
10.1101/2024.09.30.615788 — bioinformatics — Posted on 2024-10-01
5437 Evidence for Powassan virus deletions and defective RNA in field collected ticks
Langsjoen, R. M.; Courtney, S. J.; Trammel, C. E.; Robich, R. M.; Goethert, H. K.; McMinn, R. J.; Telford, S. R.; Ebel, G.; Piantadosi, A.
10.1101/2024.09.30.615485 — genomics — Posted on 2024-10-01
5438 Clade Distillation for Genome-wide Association Studies
Christ, R.; Wang, X.; Aslett, L. J. M.; Steinsaltz, D.; Hall, I.
10.1101/2024.09.30.615852 — genomics — Posted on 2024-10-01
5439 Sex-specific role of epigenetic modification of a leptin upstream enhancer in the adipose tissue
Mueller, L.; Oelkrug, R.; Mittag, J.; Hoffmann, A.; Ghosh, A.; Noe, F.; Wolfrum, C.; Jurado, E. G.; Kloeting, N.; Dietrich, A.; Blueher, M.; Kovacs, P.; Krause, K.; Keller, M.
10.1101/2024.09.30.615808 — genetics — Posted on 2024-10-01
5442 CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells
Meng, X.; Zhu, Y.; Liu, K.; Wang, Y.; Liu, X.; Liu, C.; Zeng, Y.; Wang, S.; Gao, X.; Shen, X.; Chen, J.; Tao, S.; Xu, Q.; Dong, L.; Shen, L.; Wang, L.
10.1101/2024.09.30.615805 — immunology — Posted on 2024-10-01
5443 Oddball evoked deviant responses reflect complex context dependent expectations in mouse V1
Knudstrup, S. G.; Martinez Reyes, C.; Jensen, C. M.; Schecter, R. W.; Frank, M. K.; Gavornik, J. P.
10.1101/2024.09.30.615789 — neuroscience — Posted on 2024-10-01
5444 Functional classification of tauopathy strains reveals the role of protofilament core residues.
Vaquer-Alicea, J.; Manon, V.; Bommareddy, V.; Kunach, P.; Gupta, A.; Monistrol, J.; Perez, V. A.; Tran, H. T.; Saez-Calveras, N.; Du, S.; Batra, S.; White, C. L.; Joachimiak, L. A.; Shahmoradian, S. H.; Diamond, M. I.
10.1101/2024.09.30.615521 — neuroscience — Posted on 2024-10-01
5445 Linking microscopy to diffusion MRI with degenerate biophysical models: an application of the Bayesian EstimatioN of CHange (BENCH) framework
Kor, D. Z. L.; Rafipoor, H.; Huszar, I. N.; Smart, A.; Daubney, G.; Jbabdi, S.; Cottaar, M.; Miller, K. L.; Howard, A. F. D.
10.1101/2024.09.30.615704 — neuroscience — Posted on 2024-10-01
5448 Emergent glutamate & dopamine dysfunction in VPS35(D620N) knock-in mice and rapid reversal by LRRK2 inhibition
Kamesh, A.; Kadgien, C. A.; Kuhlmann, N.; Coady, S.; Hurley, E.; Barron, J. C.; Parsons, M.; Milnerwood, A.
10.1101/2024.09.30.615858 — neuroscience — Posted on 2024-10-01
5449 The solute carrier superfamily interactome
Frommelt, F.; Ladurner, R.; Goldmann, U.; Wolf, G.; Ingles-Prieto, A.; Lineiro-Retes, E.; Gelova, Z.; Hopp, A.-K.; Christodoulaki, E.; Teoh, S. T.; Leippe, P.; Rebsamen, M.; Lindinger, S.; Serrano, I.; Onstein, S.; Klimek, C.; Barbosa, B. M. G.; Pantielieieva, A.; Dvorak, V.; Hannich, J. T.; Schoenbett, J.; Sansig, G.; Mocking, T. A. M.; Ooms, J. F.; IJzerman, A. P.; Heitman, L. H.; Sykacek, P.; Reinhardt, J.; Mueller, A. C.; Wiedmer, T.; Superti-Furga, G.
10.1101/2024.09.30.615192 — systems biology — Posted on 2024-10-01
5451 Relating GPCR domains with functionality: receptor helix-bundle and C-terminus differentially influence GRK-specific functions and β-arrestin-mediated regulation
Matthees, E. S.; Haider, R. S.; Klement, L.; Reichel, M.; Blum, N.; Weizel, V.; Truepschuh, T.; Ziegler, C.; Drube, J.; Schulz, S.; Hoffmann, C.
10.1101/2024.09.30.615794 — pharmacology and toxicology — Posted on 2024-10-01
5455 RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets
Hemm, L.; Rabsch, D.; Rae, H.; Reimann, V.; Gerth, P.; Bartel, J.; Brenes, M.; Maass, S.; Becher, D.; Hess, W. R.; Backofen, R.
10.1101/2024.09.30.615781 — bioinformatics — Posted on 2024-10-01
5458 Identification of Cellular Signatures Associated with Chinese Hamster Ovary (CHO) Cell Adaptation for Secretion of Antibodies
Bai, Y.; Mercade, I. D.; Elgendy, R.; Lambiase, G.; Peak-Chew, S. Y.; Franco, C.; Wingett, S. W.; Stevens, T. J.; Grassi, L.; Hitchcock, N.; Ferreira, C. S.; Hatton, D.; Miller, E. A.; Mistry, R. K.
10.1101/2024.09.30.614046 — bioengineering — Posted on 2024-10-01
5460 STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NFkB signaling
Fischer, T. D.; Bunker, E. N.; Zhu, P.-P.; Le Guerroue, F.; Hadjian, M.; Dominguez-Martin, E.; Scavone, F.; Cohen, R. E.; Yao, T.; Wang, Y.; Werner, A.; Youle, R. J.
10.1101/2023.10.14.562349 — cell biology — Posted on 2024-10-01
5461 Neuronal activity regulating the dauer entry decision in Caenorhabditis elegans
Prakash, S. J.; Seyedolmohadesin, M.; Zhang, M. G.; Cohen, S. M.; Gharib, S.; Venkatachalam, V.; Sternberg, P. W.
10.1101/2024.09.30.615551 — neuroscience — Posted on 2024-10-01
5462 Maintenance of neuronal TDP-43 expression requires axonal lysosome transport
Ryan, V. H.; Lawton, S.; Reyes, J. F.; Hawrot, J.; Frankenfield, A. M.; Seddighi, S.; Ramos, D. M.; Johnson, N. L.; Zou, J.; Kampmann, M.; Replogle, J.; Yuan, H.; Johnson, K. R.; Maric, D.; Hao, L.; Nalls, M. A.; Ward, M.
10.1101/2024.09.30.615241 — neuroscience — Posted on 2024-10-01
5464 The OMG dataset: An Open MetaGenomic corpus for mixed-modality genomic language modeling
Cornman, A.; West-Roberts, J.; Camargo, A. P.; Roux, S.; Beracochea, M.; Mirdita, M.; Ovchinnikov, S.; Hwang, Y.
10.1101/2024.08.14.607850 — systems biology — Posted on 2024-10-01
5465 Megakaryocytes build a cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Masson, C.; Scandola, C.; Rinckel, J.-Y.; Proamer, F.; Janus-Bell, E.; Batool, F.; OSMANI, N.; GOETZ, J. G.; Mallo, L.; Leon, C.; Bornert, A.; Poincloux, R.; destaing, o.; Lehmann, M.; Eckly, A.
10.1101/2024.09.30.615769 — physiology — Posted on 2024-10-01
5466 A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress
Teran Pumar, O. Y.; Zanotelli, M. R.; Lin, M.-c. J.; Schmitt, R. R.; Green, K. S.; Rojas, K. S.; Hwang, I. Y.; Cerione, R. A.; Wilson, K. F.
10.1101/2023.01.03.522657 — cancer biology — Posted on 2024-10-01
5469 Electromagnetic Stimulated Microfillamented Hydrogels for Guided Neuronal Morphogenesis
Jensen, B. N.; Tong, T.; Skovborg, G.; Zhang, Y.; Mueller, C.; Matthiesen, C. L.; Eschen, J. T.; Elbaek, K. J.; Wang, Y.; Pallesen, L. T.; Seliktar, D.; Dong, M.; Vaegter, C. B.; Korshoej, A. R.; Chen, M.
10.1101/2024.09.29.615659 — bioengineering — Posted on 2024-10-01
5470 A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases in vitro and in vivo ADAR-Mediated Programmable RNA Base Editing
Byrne, S. M.; Burleigh, S. M.; Fragoza, R.; Jiang, Y.; Savva, Y.; Pabon, R.; Rainaldi, J.; Portell, A.; Mali, P.; Briggs, A. W.
10.1101/2024.09.29.615721 — bioengineering — Posted on 2024-10-01
5473 Men in menopause? Experimental verification of the mate choice theory with Drosophila melanogaster shows both sexes can undergo menopause
Purohith, D.; Chaudhary, M.; Gomes, A.; Rajapakse, N.; Das, A.; Dhanvanthry, N.; Brown, M.; Mukherjee, M.; Singh, R. S.
10.1101/2022.04.18.488714 — evolutionary biology — Posted on 2024-10-01
5474 Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function
Thomas, C.; Green, S.; Kimball, L.; Schmidtke, I.; Rothwell, L.; Griffin, M.; Par, I.; Schobel, S.; Palacio, Y.; Towle-Weicksel, J. B.; Weicksel, S.
10.1101/2024.09.27.615541 — molecular biology — Posted on 2024-10-01
5475 The first complete 3D reconstruction and morphofunctional mapping of an insect eye
Makarova, A. A.; Chua, N. J.; Diakova, A. V.; Desyatirkina, I. A.; Gunn, P.; Pang, S.; Xu, C. S.; Hess, H. F.; Chklovskii, D. B.; Polilov, A. A.
10.1101/2024.09.30.615804 — zoology — Posted on 2024-10-01
5476 A transposable element insertion in IAA16 disrupts splicing and causes dicamba resistance in Bassia scoparia
Montgomery, J. S.; Soni, N.; Marques Hill, S.; Morran, S.; Patterson, E.; Edwards, S.; Ratnayake, S.; Hung, Y.-H.; Pandesha, P. H.; Slotkin, R. K.; Napier, R. M.; Dayan, F. E.; Gaines, T. A.
10.1101/2024.07.19.604363 — plant biology — Posted on 2024-10-01
5477 The Therapeutic Effects of Long-term Photobiomodulation on Aging in Mice
Ahmet, I.; Syed, S. B.; Chakir, K.; Morrell, C.; Arany, P.; Lakatta, E. G.
10.1101/2023.08.05.552116 — physiology — Posted on 2024-10-01
5478 Multi-Modal Large Language Model Enables All-Purpose Prediction of Drug Mechanisms and Properties
Liang, Y.; Zhang, R.; Li, Y.; Huo, M.; Ma, Z.; Singh, D.; Gao, C.; Rahmani, H.; Bandi, S.; Zhang, L.; Weinreb, R.; Malhotra, A.; Grotjahn, D. A.; Awdishu, L.; Ideker, T.; Gilson, M.; Xie, P.
10.1101/2024.09.29.615524 — pharmacology and toxicology — Posted on 2024-10-01
5479 Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Pham, T. H.; Pahuja, K. B.; Hagenbeek, T. J.; Zbieg, J.; Noland, C. L.; Pham, V. C.; Yao, X.; Rose, C. M.; Browder, K. C.; Lee, H.-J.; Yu, M.; Liang-Chu, M.; Martin, S. E.; Verschueren, E.; Li, J.; Kubala, M. H.; Fong, R.; Lorenzo, M.; Beroza, P.; Hsu, P.; Paul, S.; Villemure, E.; Lee, W.; Cheung, T.; Clausen, S.; Lacap, J.; Liang, Y.; Cheng, J.; Schmidt, S.; Modrusan, Z.; Cohen, M. S.; Crawford, J.; Jasper, H.; Ashworth, A.; Lill, J. R.; Malek, S.; Rudolph, J.; Wertz, I. E.; Chang, M.; Ye, X.; Dey, A.
10.1101/2023.10.03.560675 — cancer biology — Posted on 2024-10-01
5480 Lamins regulate nuclear mechanics and shape to control glioblastoma cell proliferation, migration and invasion
Wang, X.; Pereira, D.; Perfettini, I.; Peglion, F.; Wimmers, R.; Roy, A.; Forsberg-Nilsson, K.; Baffet, A.; Etienne-Manneville, S.; Manneville, J.-B.
10.1101/2024.09.30.615792 — biophysics — Posted on 2024-10-01
5486 Independent evolution of atypical sperm morphology in a passerine bird, the red-browed finch (Neochmia temporalis temporalis)
Rowe, M.; Hooper, D. M.; Hofgaard, A.; Hurley, L. L.; McDiarmid, C. S.; Pataraia, I.; Lifjeld, J. T.; Griffith, S. C.
10.1101/2024.09.30.615754 — evolutionary biology — Posted on 2024-10-01
5487 Effects of Host-Tree Foliage on Polymorphism in an Insect Pathogen
Freedman, A. S.; Huang, A. Y.; Dixon, K. P.; Polivka, C. M.; Dwyer, G.
10.1101/2024.09.29.615698 — ecology — Posted on 2024-10-01
5488 BMP signaling modulations control primitive streak patterning
Simon, G.; Plouhinec, J.-L.; Gilardi-Hebenstreit, P.; Sorre, B.; Collignon, J.
10.1101/2024.10.01.616050 — developmental biology — Posted on 2024-10-01
5492 Differential gene expression and chromatin accessibility in the medial prefrontal cortex associated with individual differences in rat behavioral models of opioid use disorder
Liu, S. X.; Muelken, P.; Maxim, Z. L.; Ramakrishnan, A.; Estill, M. S.; LeSage, M. G.; Smethells, J. R.; Shen, L.; Tran, P. V.; Harris, A. C.; Gewirtz, J. C.
10.1101/2024.02.29.582799 — neuroscience — Posted on 2024-10-01
5495 An aneuploidy epistasis map reveals metabolic vulnerabilities associated with supernumerary chromosomes in cancer
Magesh, R. Y.; Kaur, A. N.; Keller, F. N.; Frederick, A.; Tseyang, T.; Haley, J. A.; Rivera Nieves, A. M.; Liang, A. C.; Guertin, D.; Spinelli, J.; Elledge, S. J.; Watson, E. V.
10.1101/2024.09.30.615609 — cancer biology — Posted on 2024-10-01
5501 A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases in vitro and in vivo ADAR-Mediated Programmable RNA Base Editing
Byrne, S. M.; Burleigh, S. M.; Fragoza, R.; Jiang, Y.; Saava, Y.; Pabon, R.; Rainaldi, J.; Portell, A.; Mali, P.; Briggs, A. W.
10.1101/2024.09.29.615721 — bioengineering — Posted on 2024-10-01
5503 Iterative sacrificial 3D printing and polymer casting to create complex vascular grafts and multi-compartment bioartificial organs
Brassard, J. A.; Sidharthan, S. D.; Orimi, H. E.; Vdovenko, D.; Rioux, Y.; Wang, H.; Champion, K.; Lemaire, F.; Moeun, B. N.; Zhao, J.; Liang, S.; Kieffer, T. J.; Tchervenkov, J. I.; Soulez, G.; Begin-Drolet, A.; Ruel, J.; Leask, R. L.; Paraskevas, S.; Hoesli, C. A.
10.1101/2024.09.29.615298 — bioengineering — Posted on 2024-10-01
5507 Giant extrachromosomal element "Inocle" potentially expands the adaptive capacity of the human oral microbiome
Kiguchi, Y.; Hamamoto, N.; Kashima, Y.; Runtuwene, L. R.; Ishizaka, A.; Kuze, Y.; Enokida, T.; Tanaka, N.; Tahara, M.; Kageyama, S.-I.; Fujisawa, T.; Yamashita, R.; Kanai, A.; Tuda, J. S. B.; Mizutani, T.; Suzuki, Y.
10.1101/2024.09.30.615745 — genomics — Posted on 2024-10-01
5508 Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine
Schoenle, A.; Guiglielmoni, N.; Mainz, T.; Greve, C.; Hamadou, A. B.; Heermann, L.; Borcherding, J.; Waldvogel, A.-M.
10.1101/2024.04.22.590508 — genomics — Posted on 2024-10-01
5510 High-risk neuropsychiatric copy number variants are associated with convergent transcriptomic changes in human brain cells
Dugan, G.; Akula, N.; Marenco, S.; Auluck, P.; Raznahan, A.; Liu, S.; DeCasien, A. R.; Xu, Q.; Feng, N.; Kolachana, B.; Jiang, X.; Gregory, M.; Berman, K.; Hoffman, G.; Roussos, P.; McMahon, F.; Schulmann, A.
10.1101/2024.09.19.613680 — genetics — Posted on 2024-10-01
5511 Genomic stability in the Galapagos Scalesia adaptive radiation: Consistent transposable element accumulation despite hybridization and ecological niche shifts
Cerca, J.; Jaramillo Diaz, P.; Goubert, C.; Yang, H.; Bieke, V. C.; Fernandez-Mazuecos, M.; Vargas, P.; Schley, R. J.; Li, S.; Guevara-Andino, J. E.; Petersen, B.; Petersen, G.; Sinha, N.; Nielsen, L. R.; Leebens-Mack, J.; Rivas-Torres, G.; Rieseberg, L. H.; Martin, M.
10.1101/2024.09.30.614436 — evolutionary biology — Posted on 2024-10-01
5512 Population genomics for coral reef restoration - a case study of staghorn corals in Micronesia
Rios, D.; Torrado, H.; Lemer, S. M. E.; Drury, C.; Burdick, D. R.; Raymundo, L.; Combosch, D. J.
10.1101/2024.09.29.615720 — evolutionary biology — Posted on 2024-10-01
5514 FLOW CYTOMETRIC PROCEDURES FOR DEEP CHARACTERIZATION OF NANOPARTICLES
Tirelli, V.; Grasso, F.; Barreca, V.; Polignano, D.; gallinaro, a.; Cara, A.; Sargiacomo, M.; Fiani, M. L.; Sanchez, M.
10.1101/2024.07.18.604065 — cell biology — Posted on 2024-10-01
5521 Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells
Sarabipour, S.; Kinghorn, K.; Quigley, K. M.; Kovacs-Kasa, A.; Annex, B. H.; Bautch, V. L.; Mac Gabhann, F.
10.1101/2024.09.29.615728 — systems biology — Posted on 2024-10-01
5522 Phytochemical Analysis and Nematicidal Activity of Medicinal Plants Against Meloidogyne javanica
Maher, S.; Naheed, N.; Khan, N.; Ishtiaq, H.; Solangi, G. S.; karim, A.; Imran, M.; Iqbal, E.; Mukhtar, F.; Bakhshi, M.; Mina, G.; Alarfaji, S. S.
10.1101/2024.09.29.615697 — plant biology — Posted on 2024-10-01
5523 Patterns of leaf, flower and fruit phenology and environmental relationships in a seasonal tropical forest in the Indian Eastern Himalaya
Datta, A.; Banerjee, S.; Naniwadekar, R.; Thapa, K.; Rathore, A.; Thapa, K.; Brah, T.; Nabum, T.; Mogar, N.; Shukla, U.; Sidhu, S.; Borawake, N.
10.1101/2024.09.29.615687 — plant biology — Posted on 2024-10-01
5526 Efficient Derivation of Immortalized, Isogenic Cell Lines from Genetically Defined Murine Hepatoblastomas
Wang, H.; Lu, J.; Chen, K.; Ma, B.; Henchy, C.; Knapp, J.; Ranganathan, S.; Prochownik, E. V.
10.1101/2024.09.29.615692 — cancer biology — Posted on 2024-10-01
5529 STIX: Long-reads based Accurate Structural Variation Annotation at Population Scale
Zheng, X.; Chowdhury, M.; Mirpochoev, B.; Clauset, A.; Layer, R. M.; Sedlazeck, F. J.
10.1101/2024.09.30.615931 — bioinformatics — Posted on 2024-10-01
5530 Fluid Flow Impacts Endothelial-Monocyte Interactions in a Model of Vascular Inflammatory Fibrosis
Linares, I.; Chen, K.; Saffren, A.; Mansouri, M.; Abhyankar, V. V.; Miller, B. L.; Begolo, S.; Awad, H. A.; McGrath, J. L.
10.1101/2024.09.29.615690 — bioengineering — Posted on 2024-10-01
5531 Effects of Host-Tree Foliage on Polymorphism in an Insect Pathogen
Freedman, A. S.; Huang, A.; Dixon, K.; Polivka, C. M.; Dwyer, G.
10.1101/2024.09.29.615698 — ecology — Posted on 2024-10-01
5532 Integrated data from R405W desmin knock-in mice highlight alterations of mitochondrial function, protein quality control, and myofibrillar structure in the initial stages of myofibrillar myopathy
Batonnet-Pichon, S.; Delort, F.; Lilienbaum, A.; Berwanger, C.; Schultheis, D.; Schlötzer-Schrehardt, U.; Schmidt, A.; Uebe, S.; Baiche, Y.; Eisenack, T. J.; Trentini, D. B.; Mallek, M.; Mill, L.; Ferreiro, A.; Eberhard, B.; Lücke, T.; Krüger, M.; Thiel, C.; Schröder, R.; Clemen, C. S.
10.1101/2024.09.29.615655 — neuroscience — Posted on 2024-10-01
5535 High exposure variance enables candidate biomarker detection in a small EWAS of methylmercury-exposed Peruvian adults
Weinhouse, C.; Perez, L.; Ryde, I.; Goodrich, J. M.; Miranda, J. J.; Hsu-Kim, H.; Murphy, S. K.; Meyer, J. N.; Pan, W. K.
10.1101/2022.07.05.498896 — genomics — Posted on 2024-10-01
5536 Exploiting functional regions in the viral RNA genome as druggable entities
Luo, D.; Zheng, Y.; Huang, Z.; Wen, Z.; Guo, L.; Deng, Y.; Li, Q.; Bai, Y.; Haider, S.; Wei, D.
10.1101/2024.08.11.607475 — genomics — Posted on 2024-10-01
5538 Comprehensive gene expression analysis of organoid-derived healthy human colonic epithelium and cancer cell line by stimulated with live probiotic bacteria
Sen, A.; Imai, A.; Miyauchi, E.; Yanagisawa, K.; Oda, T.; Sasaki, F.; Uchida, S.; Okada, T.; Yokobori, T.; Saeki, H.; Odamaki, T.; Sasaki, N.
10.1101/2024.05.23.595631 — ecology — Posted on 2024-10-01
5539 Unbiased identification of cell identity in dense mixed neural cultures
De Beuckeleer, S.; Van De Looverbosch, T.; Van Den Daele, J.; Ponsaerts, P.; De Vos, W.
10.1101/2024.01.06.574474 — cell biology — Posted on 2024-10-01
5540 Diversification of an emerging bacterial plant pathogen; insights from the global spread of Xanthomonas euvesicatoria pv. perforans
Timilsina, S.; Iruegas-Bocardo, F.; Jibrin, M. O.; Sharma, A.; Subedi, A.; Kaur, A.; Minsavage, G. V.; Huguet-Tapia, J.; Klein-Gordon, J.; Adhikari, P.; Adhikari, T. B.; Cirvilleri, G.; Belen Tapia de la Barrera, L.; Bernal, E.; Creswell, T. C.; Doan, T. T. K.; Coutinho, T. A.; Egel, D. S.; Felix-Gastelum, R.; Francis, D. M.; Kebede, M.; Lewis Ivey, M.; Louws, F. J.; Luo, L.; Maynard, E. T.; Miller, S. A.; Nguyen, N. T. T.; Osdaghi, E.; Quezado-Duval, A. M.; Roach, R.; Rotondo, F.; Ruhl, G. E.; Shutt, V. M.; Thummabenjapone, P.; Trueman, C.; Roberts, P. D.; Jones, J. B.; Vallad, G. E.; Goss, E
10.1101/2024.03.22.585974 — microbiology — Posted on 2024-10-01
5541 SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in-vitro and in-vivo
Jakhar, K.; Sonar, S.; Singh, G.; Asuru, T. R.; Joshi, G.; Beniwal, N.; Sarkar, T.; Tiwari, M.; Kaur, J.; Rathore, D. K.; Lal, B.; Kumar, S.; Srivastav, P.; Kumar, S.; Phagna, V.; Sushma, ; Kumar, L.; Gupta, V.; Kshetrapal, P.; Singh, S.; Wadhwa, N.; Thiruvengadam, R.; Raghavan, S.; Gosain, M.; Shrivastava, T.; Bhattacharyya, S.; Asthana, S.; Guchhait, P.; Mani, S.
10.1101/2023.10.09.557914 — immunology — Posted on 2024-10-01
5542 Roles of Kdm6a and Kdm6b in regulation of mammalian neural regeneration
Yang, S.-G.; Wang, X.-W.; Li, C.-P.; Huang, T.; Qian, C.; Li, Q.; Zhao, L.; Zhou, S.-Y.; Saijilafu, ; Liu, C.-M.; Zhou, F.-Q.
10.1101/2023.09.12.557354 — neuroscience — Posted on 2024-10-01
5543 Modeling and Simulation of Rat Non-Barrel Somatosensory Cortex. Part I: Modeling Anatomy
Reimann, M. W.; Bolanos Puchet, S.; Egas Santander, D.; Courcol, J.-D.; Arnaudon, A.; Coste, B.; Delemontex, T.; Devresse, A.; Dictus, H.; Dietz, A.; Ecker, A.; Favreau, C.; Ficarelli, G.; Gevaert, M.; Hernando, J. B.; Herttuainen, J.; Isbister, J. B.; Kanari, L.; Keller, D.; King, J. G.; Kumbhar, P.; Lapere, S.; Lazovskis, J.; Lu, H.; Ninin, N.; Pereira, F.; Planas, J.; Pokorny, C.; Riquelme, J. L.; Romani, A.; Shi, Y.; Smith, J. P.; Sood, V.; Srivastava, M.; Van Geit, W.; Vanherpe, L.; Wolf, M.; Levi, R.; Hess, K.; Schürmann, F.; Muller, E. B.; Ramaswamy, S.; Markram, H.
10.1101/2022.08.11.503144 — neuroscience — Posted on 2024-10-01
5547 Data Hunters: bridging bioinformatics education and microbiome research
Fumagalli, S.; Armanni, A.; Casiraghi, M.; Corneo, L.; Ghisleni, G.; Labra, M.; Bruno, A.
10.1101/2024.09.27.615386 — scientific communication and education — Posted on 2024-10-01
5548 Seed specific overexpression of a modified wheat Or gene leads to enhanced β-carotene in rice and wheat grains
Sirohi, P.; Vishnoi, R.; Baliyan, S.; Gupta, B. B.; Demiwal, P.; Germain, H.; Sircar, D.; Chauhan, H.
10.1101/2024.09.28.615562 — plant biology — Posted on 2024-10-01
5549 Targeting an Olfactory Receptor Mitigates High Residual Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Depolymerization
Aggarwal, A.; Josyula, V. P.; Wang, N.; Yang, M.; Shim, Y. J.; Quinn, K.; Samuel, R.; Sangwan, N.; Guntupalli, S.; Godwin, M.; Ali, M.; Jennings, C.; Rajasekar, B.; Scalise, A.; Park, H. E.; Stauffer, S.; McCrae, K.; McIntyre, T. M.; Cameron, S.
10.1101/2024.09.30.615956 — physiology — Posted on 2024-10-01
5553 A Wearable Mindfulness Brain-Computer Interface for Alleviating Car Sickness
Zhu, J.; Bao, X.; Huang, Q.; Wang, T.; Huang, L.; Han, Y.; Huang, H.; Zhu, J.; Qu, J.; Li, K.; Chen, D.; Jiang, Y.; Xu, K.; Wang, Z.; Wu, W.; Li, Y.
10.1101/2024.09.25.614936 — bioengineering — Posted on 2024-10-01
5554 Genome organization by SATB1 binding to base-unpairing regions (BURs) provides scaffold for SATB1-regulated gene expression
Kohwi, Y.; Wong, X.; Grange, M.; Sexton, T.; Richards, H. W.; Kitagawa, Y.; Sakaguchi, S.; Liang, Y.-C.; Chuong, C.-M.; Botchkarev, V.; Taniguchi, I.; Reddy, K. L.; Kohwi-Shigematsu, T.
10.1101/2021.12.19.473323 — genomics — Posted on 2024-10-01
5555 Chromosome-level genome assembly of a doubled haploid brook trout (Salvelinus fontinalis)
Lecomte, L.; Ferchaud, A.-L.; Normandeau, E.; Merot, C.; Langlois-Parise, I.; Therrien, J.-C.; Berube, P.; Djambazian, H.; Nawarathna, P. M.; Fraser, D.; Ragoussis, J.; Bernatchez, L.
10.1101/2024.09.27.615458 — genomics — Posted on 2024-10-01
5557 CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility
Wu, B.; Long, C.; Yang, Y.; Zhang, Z.; Ma, S.; Ma, Y.; Wei, H.; Li, J.; Jiang, H.; Li, W.; Liu, C.
10.1101/2024.04.12.589289 — developmental biology — Posted on 2024-10-01
5558 Morphomechanic tuning of ERK by actin-TFII-IΔ regulates cell identity
Wu, Q.; Zhang, J.; Long, B.; Hu, X.; Mafra de Faria, B.; Scalf, S. M.; Karatepe, K.; Cao, W.; Tsopoulidis, N.; Binkercosen, A.; Yagi, M.; Weiner, A.; Kaileh, M.; De La Cruz, E. M.; Roy, A. L.; Hochedlinger, K.; Guo, S.
10.1101/2023.06.02.543427 — cell biology — Posted on 2024-10-01
5561 Quorum sensing and DNA methylation play active roles in clinical Burkholderia phase variation
Coulon, P. M. L. .; Groleau, M.-C.; Hachani, A.; Padula, M. P.; Stinear, T. P.; Deziel, E.
10.1101/2024.09.30.615881 — microbiology — Posted on 2024-10-01
5563 Oscillatory dynamics of sustained attention states
Solis-Vivanco, R.; Barne, L. C.; Harris, A. M.; Liu, X.; Lavie, N.
10.1101/2024.09.25.614991 — neuroscience — Posted on 2024-10-01
5565 Neural mechanisms of awareness of action
Jin, D. S.; Agdali, O.; Yadav, T.; Kronemer, S. I.; Kunkler, S.; Majumder, S.; Khurana, M.; McCusker, M. C.; Fu, I.; Siff, E. J.; Khalaf, A.; Christison-Lagay, K. L.; Aerts, S. L.; Xin, Q.; Li, J.-J.; McGill, S. H.; Crowley, M. J.; Blumenfeld, H.
10.1101/2024.08.15.608153 — neuroscience — Posted on 2024-10-01
5567 Dynamic Modulation of Representational Trajectories Through Selective Attention
Zhou, Y.; Zhang, L.; Axmacher, N.; Pacheco Estefan, D.; Wang, D.; Dai, Y.; Peng, X.; Xue, G.
10.1101/2024.01.21.576506 — neuroscience — Posted on 2024-10-01
5569 Cortical tracking of postural sways during standing balance.
Legrand, T.; Mongold, S. J.; Muller, L.; Naeije, G.; Vander Ghinst, M.; Bourguignon, M.
10.1101/2023.12.08.570752 — neuroscience — Posted on 2024-10-01
5571 Brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning
Mohar, B.; Michel, G.; Wang, Y.-Z.; Hernandez, V.; Grimm, J. B.; Park, J.-Y.; Patel, R.; Clarke, M.; Brown, T. A.; Bergmann, C.; Gebis, K. K.; Wilen, A. P.; Liu, B.; Johnson, R.; Graves, A.; Tchumatchenko, T.; Savas, J. N.; Fornasiero, E. F.; Huganir, R. L.; Tillberg, P.; Lavis, L. D.; Svoboda, K.; Spruston, N.
10.1101/2022.11.12.516226 — neuroscience — Posted on 2024-10-01
5574 Combining video telemetry and wearable MEG for naturalistic imaging
O'Neill, G. C.; Seymour, R. A.; Mellor, S.; Alexander, N.; Tierney, T. M.; Bernachot, L.; Fahimi Hnazee, M.; Spedden, M. E.; Timms, R. C.; Bush, D.; Bestmann, S.; Brookes, M. J.; Barnes, G. R.
10.1101/2023.08.01.551482 — neuroscience — Posted on 2024-10-01
5578 Unsaturation and Approximate Isotopic Homogeneity in Leaf Air Spaces
Collaviti, S. E.; Stuart-Williams, H.; Farquhar, G. D.; Cernusak, L. A.; Marquez, D. A.
10.1101/2024.09.30.610858 — plant biology — Posted on 2024-10-01
5580 Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplast
Buscaill, P.; Sanguankiattichai, N.; Kaschani, F.; Huang, J.; Mooney, B. C.; Li, Y.; Lyu, J.; Sueldo, D. J.; Kaiser, M.; van der Hoorn, R. A. L.
10.1101/2024.05.23.595557 — plant biology — Posted on 2024-10-01
5581 Directed evolution of a plant immune receptor for broad spectrum recognition of pathogen effectors
Rim, E. Y.; Garrett, O. D.; Howard, A. J.; Shim, Y.; Li, Y.; Van Dyke, J. E.; Packer, R. C.; Ho, N.; Jain, R. S.; Stewart, V. J.; Dinesh-Kumar, S. P.; Notwell, J. H.; Ronald, P. C.
10.1101/2024.09.30.614878 — plant biology — Posted on 2024-10-01
5582 Raffinose induces autophagy to promote plant growth
Magen, S.; Daniel, S.; Weiss, S.; Factor, D. J.; Mursalimov, S.; Soroka, Y.; Michaeli, S.; Avin-Wittenberg, T.
10.1101/2024.09.02.610801 — plant biology — Posted on 2024-10-01
5583 IQD2 recruits KLCR1 to the membrane-microtubule nexus to promote cytoskeletal mechano-responsiveness in leaf epidermis pavement cells
Buhl, J.; Klemm, S.; Koelling, M.; Ruhnow, F.; Ihling, C.; Tueting, C.; Dahiya, P.; Patzsch, J.; Colin, L.; Stamm, G.; Kastritis, P. L.; Sinz, A.; Persson, S.; Buerstenbinder, K.
10.1101/2024.10.01.615909 — plant biology — Posted on 2024-10-01
5584 Comparison of morphological and physiological response to drought stress among temperate forest understory forbs and graminoids
Petek-Petrik, A.; Petrik, P.; Halmova, M.; Plichta, R.; Matouskova, M.; Houskova, K.; Chudomelova, M.; Urban, J.; Hedl, R.
10.1101/2024.10.01.615773 — plant biology — Posted on 2024-10-01
5585 Organic macromolecules transport a significant proportion of the calcium precursor for nacre formation.
Macias-Sanchez, E.; Huang, X.; Willinger, M. G.; Rodriguez-Navarro, A. B.; Checa, A. G.
10.1101/2024.01.28.577631 — biophysics — Posted on 2024-10-01
5589 SMARTER-database: a tool to integrate SNP arraydatasets for sheep and goat breeds
Cozzi, P.; Manunza, A.; Ramirez-Diaz, J.; Tsartsianidou, V.; Gkagkavouzis, K.; Peraza, P.; Johansson, A. M.; Arranz, J. J.; Freire, F.; Kusza, S.; Biscarini, F.; Peters, L.; Tosser-Klopp, G.; Ciappesoni, G.; Triantafyllidis, A.; Rupp, R.; Servin, B.; Stella, A.
10.1101/2024.09.01.610681 — bioinformatics — Posted on 2024-10-01
5591 Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells
Grzywa, T.; Mehta, N.; Cossette, B.; Romanov, A.; Paruzzo, L.; Ramasubramanian, R.; Cozzone, A.; Morgan, D.; Sukaj, I.; Bergaggio, E.; Tannir, R.; Kadauke, S.; Myers, R.; Yousefpour, P.; Ghilardi, G.; Schuster, S.; Neeser, A.; Frey, N.; Goncalves, B.; Zhang, L.; Abraham, W.; Suh, H.; Ruella, M.; Grupp, S.; Chiarle, R.; Wittrup, K. D.; Ma, L.; Irvine, D. J.
10.1101/2024.04.16.589780 — bioengineering — Posted on 2024-10-01
5592 Control of Physical and Biochemical Parameters Influencing Exogeneous Cargo Protein association to Extracellular Vesicle using Lipid Anchors Enables High Loading and Effective Intracellular Delivery
Marquant, A.; Berthelot, J.; Bich, C.; Ibn Elfekih, Z.; Simon, L.; Robin, B.; Chopineau, J.; Tianpei Wang, D.; Jay Emerson, S.; Wang, A.; Benedetti, C.; Langlois, S.; Guglielmi, L.; Martineau, P.; Aubert-Pouessel, A.; Morille, M.
10.1101/2024.08.28.610030 — bioengineering — Posted on 2024-10-01
5593 Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans
Ota, T.; Takayama, M.; Ishihara, T.; Sato, M.; Ono, S.; Futamata, R.; Fujitani, M.; Rokushima, M.
10.1101/2024.09.24.613422 — biochemistry — Posted on 2024-10-01
5597 Mutualisms within light microhabitats drive sensory convergence in a mimetic butterfly community
Wainwright, J. B.; Loupasaki, T.; Ramirez, F.; Penry-Williams, I. L.; England, S. J.; Barker, A.; Meier, J.; How, M. J.; Roberts, N. W.; Troscianko, J.; Montgomery, S. H.
10.1101/2024.08.16.607924 — evolutionary biology — Posted on 2024-10-01
5599 S1PR1 Regulates Lymphatic Valve Development And Prevents Ileitis-Independent Tertiary Lymphoid Organ Formation
Geng, X.; Chen, L.; Ahmed, Z.; Formigari, G. P.; Ho, Y.; Gaudio, I. D.; Datilo, M. N.; Azartash-Namin, Z. J.; Shan, X.; Keshari, R. S.; Chen, H.; Lupu, F.; Xia, L.; Randolph, G. J.; Zawieja, S. D.; Camerer, E.; Davis, M. J.; Srinivasan, R. S.
10.1101/2024.09.30.615915 — developmental biology — Posted on 2024-10-01
5600 Specific Mitotic Events Drive Cytoskeletal Remodeling Required for Left-Right Organizer Development
Wu, Y.; Lan, Y.; Ononiwu, F.; Poole, A.; Rasmussen, K.; Da Silva, J.; Shamil, A. W.; Jao, L.-E.; Hehnly, H.
10.1101/2024.05.12.593765 — developmental biology — Posted on 2024-10-01
5605 Progesterone induces meiosis through two obligate co-receptors with PLA2 activity
Nader, N.; Assaf, L.; Zarif, L.; Halama, A.; Yadav, S.; Dib, M.; Attarwala, N.; Chen, Q.; Suhre, K.; Gross, S. S.; Machaca, K.
10.1101/2023.09.09.556646 — cell biology — Posted on 2024-10-01
5606 DNA methylation protects cancer cells against senescence
Chen, X.; Yamaguchi, K.; Rodgers, B.; Goerhig, D.; Vindrieux, D.; Lahaye, X.; Nolot, M.; Ferry, L.; Martin, N.; Dubus, P.; Miura, F.; Ito, T.; Manel, N.; Kanemaki, M.; Bernard, D.; Defossez, P.-A.
10.1101/2024.08.23.609297 — molecular biology — Posted on 2024-10-01
5607 Autism-associated PTCHD1 missense variants bind to the SNARE-associated protein, SNAPIN, but exhibit impaired subcellular trafficking
Pastore, S. F.; Xie, C. T. Y.; Derwish, R.; Muhammad, T.; Blahova, T.; El-masri, S.; Frankland, P.; Hamel, P. A.; Vincent, J. B.
10.1101/2024.02.29.582618 — molecular biology — Posted on 2024-10-01
5610 The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis
Li, Q.; Lim, K. Y.; Altawell, R.; Verderose, F.; Li, X.; Dong, W.; Martinez, J.; Dickman, D.; Stavropoulos, N.
10.1101/689471 — neuroscience — Posted on 2024-10-01
5612 The utility of explainable A.I. for MRI analysis: Relating model predictions to neuroimaging features of the aging brain
Hofmann, S. M.; Goltermann, O.; Scherf, N.; Mueller, K.-R.; Loeffler, M.; Villringer, A.; Gaebler, M.; Witte, A. V.; Beyer, F.
10.1101/2024.09.27.615357 — neuroscience — Posted on 2024-10-01
5614 Total cerebral blood volume changes drive macroscopic cerebrospinal fluid flux in humans
Zimmermann, J.; Boudriot, C.; Eipert, C.; Hoffmann, G.; Nuttall, R.; Neumaier, V.; Bonhoeffer, M.; Schneider, S.; Schmitzer, L.; Kufer, J.; Kaczmarz, S.; Hedderich, D.; Ranft, A.; Golkowski, D.; Priller, J.; Zimmer, C.; Ilg, R.; Schneider, G.; Preibisch, C.; Sorg, C.; Zott, B.
10.1101/2023.04.13.536674 — neuroscience — Posted on 2024-10-01
5615 Pulsatile basal gene expression as a fitness determinant in bacteria
Jain, K.; Hauschild, R.; Bochkareva, O. O.; Roemhild, R.; Tkacik, G.; Guet, C. C.
10.1101/2024.09.30.615870 — systems biology — Posted on 2024-10-01
5618 Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity
Pires, M. J.; Lovric, A.; Alam, S.; Fabbrizi, E.; Rotili, D.; Altun, M.; Valerie, N. C. K.
10.1101/2024.08.09.607390 — biochemistry — Posted on 2024-10-01
5620 Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts
Wei, J.; Resztak, J. A.; Ranjbaran, A.; Alazizi, A.; Mair-Meijers, H. E.; Slatcher, R. B.; Zilioli, S.; Wen, X.; Luca, F.; Pique-Regi, R.
10.1101/2023.12.24.573260 — genomics — Posted on 2024-10-01
5621 Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans
Huang, J.; Larmore, C. J.; Priest, S. J.; Xu, Z.; Dietrich, F. S.; Yadav, V.; Magwene, P. M.; Sun, S.; Heitman, J.
10.1101/2024.08.15.608186 — genetics — Posted on 2024-10-01
5622 Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54xCam3.II P. falciparum genetic cross.
Kanai, M.; Mok, S.; Yeo, T.; Shears, M. J.; Ross, L. S.; Jeon, J. H.; Narwal, S.; Haile, M. T.; Tripathi, A. K.; Mlambo, G.; Kim, J.; Gil-Iturbe, E.; Okombo, J.; Fairhurst, K. J.; Bloxham, T.; Bridgford, J. L.; Sheth, T.; Ward, K. E.; Park, H.; Rozenberg, F. D.; Quick, M.; Mancia, F.; Lee, M. C.; Small-Saunders, J. L.; Uhlemann, A.-C.; Sinnis, P.; Fidock, D. A.
10.1101/2024.09.27.615529 — genetics — Posted on 2024-10-01
5626 A miRNA screen identifies a transcriptional program controlling the fate of adult stem cell
Robert, J.; Vlachavas, E.-I.; Lemaitre, G.; Chatziioannou, A.; Puceat, M.; Delom, F.; Fessart, D.
10.1101/314658 — cell biology — Posted on 2024-10-01
5627 Calcium Homeostasis Modulator 2 Constitutes an ATP-regulation Pore in Mitochondria
GUO, Q.; Hou, T.; Xie, W.-J.; Zhang, J.-R.; Ma, X.-L.; Guo, Y.; Wang, X.-T.; Wang, L.-P.; Lu, M.-A.; Wu, Z.; Wang, H.-G.; Chen, Y.-H.; Li, Y.-L.; Wang, S.-Q.
10.1101/2024.09.30.615983 — cell biology — Posted on 2024-10-01
5628 Hypomorphic NOTCH1 Expression Alters Cardiomyocyte Cellular Architecture in Hypoplastic Left Heart Syndrome
Lewis, J.; Lear, T.; Woods, D.; Rao, K. S.; Amy, S.; Tan, X.; Javed, Z.; Jagannathan, R.; Nelson, T.; Moulik, M.; Hempel, N.; Chen, B.; Shiva, S.; Rajasundaram, D.; Finkel, T.; Saraf, A.
10.1101/2024.09.30.615809 — cell biology — Posted on 2024-10-01
5630 Plasma Membrane Remodelling in GM2 Gangliosidoses Drives Synaptic Dysfunction
Nicholson, A. S.; Priestman, D. A.; Antrobus, R.; Williamson, J. C.; Bush, R.; Barrow, H. G.; Smith, E.; Dobrenis, K.; Bright, N. A.; Platt, F. M.; Deane, J. E.
10.1101/2024.08.20.608810 — neuroscience — Posted on 2024-10-01
5638 CLYBL averts methylmalonyl-CoA mutase inhibition and loss of vitamin B12 by repairing malyl-CoA
Griffith, C. M.; Conrotte, J.-F.; Paydar, P.; Xie, X.; Heins Marroquin, U.; Gavotto, F. M.; Jäger, C.; Ellens, K. W.; Linster, C. L.
10.1101/2024.09.25.614871 — biochemistry — Posted on 2024-10-01
5642 RO8191, a new compound for initiating embryoimplantation in mice
Shu, J.; Terakawa, J.; Osuka, S.; Muraoka, A.; Ruan, J.; Ito, J.; Iida, A.; Hondo, E.
10.1101/2024.09.30.615945 — developmental biology — Posted on 2024-10-01
5648 Titin-dependent biomechanical feedback tailors sarcomeres to specialised muscle functions in insects
Loreau, V.; Koolhaas, W.; Chan, E. H.; De Bossier, P.; Brouilly, N.; Avosani, S.; Sane, A.; Pitaval, C.; Reiter, S.; Luis, N. M.; Mangeol, P.; von Philipsborn, A. C.; Rupprecht, J.-F.; Goerlich, D.; Habermann, B. H.; Schnorrer, F.
10.1101/2024.09.30.615857 — developmental biology — Posted on 2024-10-01
5649 The multimodal transcriptional response of denervated skeletal muscle involves alterations in cholesterol homeostasis impacting muscle size
Calvo, C.; Swoboda, C.; Montecino, F.; Nagar, S.; Petrany, M.; Sun, C.; Durumutla, H.; Quattrocelli, M.; Millay, D.
10.1101/2024.09.30.615874 — cell biology — Posted on 2024-10-01
5651 The Deubiquitinating Enzyme Otub2 Modulates Pancreatic Beta-Cells Function and Survival
Oshry, M.; Isaac, R.; Boura-Halfon, S.; Sampson, S.; Lev, S.; Zick, Y.; Vinik, Y.
10.1101/2024.09.30.615641 — cell biology — Posted on 2024-10-01
5654 Liver Sinusoidal Endothelial Cells and Laminin dictate cholangiocytes fate in chronic liver disease
Manco, R.; Moliterni, C.; Neirynck, G.; De Rudder, M.; Picalausa, C.; Ducor, L.; Fraga, M.; Lemaigre, F.; Sempoux, C.; Dili, A.; Leclercq, I. A.
10.1101/2024.09.29.615650 — cell biology — Posted on 2024-10-01
5655 TET2 contributes to gluconeogenesis and pathology of type 2 diabetes
Zhang, X.; Li, H.; Li, S.; Cui, Z.; Zhao, X.; Ma, H.; Xu, M.; Xu, Y.
10.1101/2024.09.29.615677 — cell biology — Posted on 2024-10-01
5656 Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers
Follain, G.; Ghimire, S.; Pylvänäinen, J. W.; Vaitkeviciute, M.; Wurzinger, D. H.; Guzman, C.; Conway, J. R.; Dibus, M.; Oikari, S.; Rilla, K.; Salmi, M.; Ivaska, J.; Jacquemet, G.
10.1101/2024.09.30.615654 — cell biology — Posted on 2024-10-01
5657 Mechanical Centrosome Fracturing during Cell Navigation
Schmitt, M. T.; Ruiz-Fernandez, M. J. A.; Stefanowski, K.; Kroll, J.; Hauschild, R.; Merrin, J.; Penz, T.; Kiermaier, E.; Bock, C.; Straub, T.; Renkawitz, J.
10.1101/2024.10.01.615992 — cell biology — Posted on 2024-10-01
5658 Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing
De Castro, I.; Schuster, L.; Gomez, C. P.; Glavas, D.; Udupa, A.; Vazquez, M. R.; Symens, T.; Tulcan, G.; de las Heras, J. I.; Reinhardt, R.; Trojanowski, J.; Harz, H.; Stumberger, G.; Leonhardt, H.; Schirmer, E. C.; Saka, S.; Laketa, V.; Lusic, M.
10.1101/2024.09.30.615666 — cell biology — Posted on 2024-10-01
5659 Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
Lam, B.; Kajderowicz, K. M.; Keys, H. R.; Roessler, J. M.; Frenkel, E. M.; Kirkland, A.; Bisht, P.; El-Brolosy, M. A.; Jaenisch, R.; Bell, G. W.; Weissman, J. S.; Griffith, E. C.; Hrvatin, S.
10.1101/2024.07.25.605098 — cell biology — Posted on 2024-10-01
5660 Mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection
Hsieh, L. T.-H.; Hall, B. S.; Newcombe, J.; Mendum, T. A.; Santana-Varela, S.; Umrania, Y.; Deery, M. J.; Shi, W. Q.; Diaz Delgado, J.; Salguero, F. J.; Simmonds, R. E.
10.1101/2023.02.21.529382 — microbiology — Posted on 2024-10-01
5661 Unraveling Axonal Transcriptional Landscapes: Insights from iPSC-Derived Cortical Neurons and Implications for Motor Neuron Degeneration
Xu, J.; Hoerner, M.; Nagel, M.; Perhat, P.; Korneck, M.; Noss, M.; Hauser, S.; Schoels, L.; Admard, J.; Casadei, N.; Schuele, R.
10.1101/2024.03.26.586780 — neuroscience — Posted on 2024-10-01
5662 Serotonergic neurons in the dorsal raphe regulate visual attention
Lehnert, J.; Cha, K.; Forestell, J.; Yang, K.; Ma, X.; Britt, J.; Khadra, A.; Cook, E. P.; Krishnaswamy, A.
10.1101/2024.09.29.615662 — neuroscience — Posted on 2024-10-01
5664 UBE3A reinstatement restores behavior and proteome in an Angelman Syndrome mouse model of Imprinting Defects
Milazzo, C.; Narayanan, R.; Badillo, S.; Wang, S.; Almand, R.; Mientjes, E.; Chamberlain, S.; Kremer, T.; Elgersma, Y.
10.1101/2024.09.29.615689 — neuroscience — Posted on 2024-10-01
5665 Proximity proteomics reveals a co-evolved LRRK2-regulatory network linked to centrosomes
Eckert, M.; Miglionico, P.; Izzi, F.; De Oliveira Rosa, N.; Ueffing, M.; Raimondi, F.; Gloeckner, C. J.
10.1101/2024.09.30.613622 — neuroscience — Posted on 2024-10-01
5669 Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome
Ganesan, S.; Murray, R. M.; Sotelo, J.; Eton, E. O.; Takashima, K.; Botella, T.; Beattie, K.; Indart, A. C.; Chraiki, N.; Croizier, C.; Izzo, F.; Potenski, C.; Marro, S.; Wu, Z.; Gao, S.; Young, N. S.; Blair, J. D.; Satija, R.; Terrier, B.; Heiblig, M.; Raimondi, I.; Papapetrou, E. P.; Sujobert, P.; Kosmider, O.; Beck, D. B.; Landau, D. A.
10.1101/2024.05.19.594376 — genomics — Posted on 2024-10-01
5670 Exploiting functional regions in the viral RNA genome as druggable entities
Luo, D.; Zheng, Y.; Huang, Z.; Wen, Z.; Guo, L.; Deng, Y.; Li, Q.; Bai, Y.; Haider, S.; Wei, D.
10.1101/2024.08.11.607475 — genomics — Posted on 2024-10-01
5673 Like mother, like daughter? Phenotypic plasticity, environmental covariation, and heritability of size in a parthenogenetic wasp
Tovar, A.; Monahan, S.; Mugoya, T.; Kristan, A.; Welch, W.; Dettmers, R.; Arce, C.; Buck, T.; Ruben, M.; Rothenberg, A.; Saisho, R.; Cartmill, R.; Skaggs, T.; Reyes, R.; Lee, M.; Obrycki, J. J.; Kristan, W.; Sethuraman, A.
10.1101/2022.12.02.518902 — evolutionary biology — Posted on 2024-10-01
5674 A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro
Medina-Cano, D.; Islam, M. T.; Petrova, V.; Dixit, S.; Balic, Z.; Yang, M. G.; Stadtfeld, M.; Wong, E. S.; Vierbuchen, T.
10.1101/2024.09.30.615887 — developmental biology — Posted on 2024-10-01
5675 Axolotl epigenetic clocks offer insights into the nature of negligible senescence
Haluza, Y.; Zoller, J. A.; Lu, A. T.; Walters, H. E.; Lachnit, M.; Lowe, R.; Haghani, A.; Brooke, R. T.; Park, N.; Yun, M. H.; Horvath, S.
10.1101/2024.09.09.611397 — developmental biology — Posted on 2024-10-01
5676 A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factor
Volkening, J. D.; Spatz, S. J.; Garcia, M.; Ross, T. A.; Maekawa, D. A.; Rosenthal, K. S.; Zamora, A. C.; Skipper, A.; Blakey, J.; Paudel, R.
10.1101/2024.07.10.602945 — microbiology — Posted on 2024-10-01
5677 Dietary regulation of silent synapses in the dorsolateral striatum
Meyers, A. M.; Gnazzo, F.; Barrera, E. D.; Nabatian, T.; Chan, L.; Beeler, J. A.
10.1101/2024.03.24.586457 — neuroscience — Posted on 2024-10-01
5678 Deep learning and cross-species analysis identify the influences of sex and cannabinoidsignaling on cerebellar vermis morphology
Black, K. C.; Pandey, O.; McPherson, B. C.; Hainline, J.; Baygani, S.; Webb, B.; Mier, T. J.; Essex, A.; Mackie, K.; Pestilli, F.; Kalinovsky, A.
10.1101/2021.07.03.450642 — neuroscience — Posted on 2024-10-01
5680 Developing peptide-based fusion inhibitors as an antiviral strategy utilizing Coronin 1 as a template
Panda, M. S.; Qazi, B.; Vishwakarma, V.; Pattnaik, G. P.; Haldar, S.; Chakraborty, H.
10.1101/2024.07.04.602150 — biophysics — Posted on 2024-10-01
5682 Profiling drug sensitivity of leukemic stem cells via bulk-to-single-cell deconvolution
Alexandre, C.; Forey, R.; Bejar Haro, B.; Martins, F.; Carlevaro-Fita, J.; Sheppard, S.; Offner, S. E.; La Manno, G.; Obozinski, G.; Trono, D.
10.1101/2023.05.10.540140 — bioinformatics — Posted on 2024-10-01
5683 Origin and development of uniparental and polyploid blastomeres
Zhao, Y.; Fernandez-Montoro, A.; Peeters, G.; Jatsenko, T.; De Coster, T.; Angel-Velez, D.; Lefevre, T.; Voet, T.; Tsuiko, O.; Kurg, A.; Smits, K.; Van Soom, A.; Vermeesch, J. R.
10.1101/2024.07.30.605883 — genetics — Posted on 2024-10-01
5684 An H3-K9-me-independent binding of Swi6/HP1 to siRNA-DNA hybrids initiates heterochromatin assembly at cognate dg-dh repeats in Fission Yeast
Singh, J.; Kumar, J.; Haldar, S.; Gupta, N.; Kumar, V.; Thakur, M.; Chandradoss, K. R.; Ghose, D.; Dutta, D.; Sandhu, K. S.
10.1101/2020.10.21.349050 — genetics — Posted on 2024-10-01
5685 Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA
Casu, B.; Sallmen, J. W.; Haas, P. E.; Chandra, G.; Afanasyev, P.; Xu, J.; Schlimpert, S.; Pilhofer, M.
10.1101/2024.06.25.600559 — microbiology — Posted on 2024-10-01
5686 Potentiation of active locomotor state by spinal-projecting serotonergic neurons
Fenstermacher, S.; Vonasek, A.; Gattuso, H.; Chaimowitz, C.; Dymecki, S.; Jessell, T.; Dasen, J.
10.1101/2024.09.26.615260 — neuroscience — Posted on 2024-10-01