bioRxiv directory

Yanez, J. M.; Yoshida, G.; Barria, A.; Palma-Vejares, R.; Travisany, D.; Diaz-Dominguez, D.; Caceres, G.; Cadiz, M. I.; Lopez, M. E.; Lhorente, J. P.; Jedlicki, A.; Soto, J.; Salas, D.; Maass, A.

10.1101/594671 — genomics — Posted on 2019-03-31

24 Catching the big picture of the Mediterranean Sea biodiversity with an end-to-end model of climate and fishing impacts

Moullec, F.; Velez, L.; Verley, P.; Barrier, N.; Ulses, C.; Carbonara, P.; Esteban, A.; Follesa, C.; Gristina, M.; Jadaud, A.; Ligas, A.; Lopez Diaz, E.; Maiorano, P.; Peristeraki, P.; Spedicato, M. T.; Thasitis, I.; Valls, M.; Guilhaumon, F.; Shin, Y.-J.

10.1101/593822 — ecology — Posted on 2019-03-31

25 Stress-induced neuronal hypertrophy decreases the intrinsic excitability in stress habituation

Matovic, S.; Ichiyama, A.; Igarashi, H.; Salter, E.; Wang, X. F.; Henry, M.; Vernoux, N.; Tremblay, M.-E.; Inoue, W.

10.1101/593665 — neuroscience — Posted on 2019-03-31

26 A high throughput multi-locus insecticide resistance marker panel for tracking resistance emergence and spread in Anopheles gambiae

Lucas, E.; Rockett, K. A.; Lynd, A.; Essandoh, J.; Grisales, N.; Kemei, B.; Njoroge, H.; Hubbart, C.; Rippon, E. J.; Morgan, J.; Van't Hof, A.; Ochomo, E. O.; Kwiatkowski, D. P.; Weetman, D.; Donnelly, M. J.

10.1101/592279 — evolutionary biology — Posted on 2019-03-31

27 A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain

Ercan-Herbst, E.; Schoendorf, D. C.; Behrendt, A.; Klaus, B.; Gomez Ramos, B.; Weber, C.; Ehrnhoefer, D. E.

10.1101/594820 — neuroscience — Posted on 2019-03-31

28 Three new integration vectors and fluorescent proteins for use in the opportunistic human pathogen Streptococcus pneumoniae

Keller, L. E.; Rueff, A.-S.; Kurushima, J.; Veening, J.-W.

10.1101/594697 — microbiology — Posted on 2019-03-31

29 Activation of a zinc metallochaperone by the alarmone ZTP

Chandrangsu, P.; Huang, X.; Helmann, J. D.

10.1101/594382 — microbiology — Posted on 2019-03-31

30 A Human Tissue-Specific Transcriptomic Analysis Reveals that Ageing Hinders Cancer and Boosts Cellular Senescence

Chatsirisupachai, K.; Palmer, D.; Ferreira, S.; de Magalhaes, J. P.

10.1101/595041 — cancer biology — Posted on 2019-03-31

31 AlbaTraDIS: Comparative analysis of large datasets from parallel transposon mutagenesis experiments

Page, A. J.; Bastkowski, S.; Yasir, M.; Turner, K.; Le Viet, T.; Savva, G.; Webber, M.; Charles, I. G.

10.1101/593624 — bioinformatics — Posted on 2019-03-31

32 Modeling longitudinal imaging biomarkers with parametric Bayesian multi-task learning

Aksman, L. M.; Scelsi, M. A.; Marquand, A. F.; Alexander, D. C.; Ourselin, S.; Altmann, A.

10.1101/593459 — neuroscience — Posted on 2019-03-31

33 A likelihood method for estimating present-day human contamination in ancient DNA samples using low-depth haploid chromosome data

Moreno-Mayar, J. V.; Korneliussen, T. S.; Albrechtsen, A.; Dalal, J.; Renaud, G.; Nielsen, R.; Malaspinas, A.-S.

10.1101/594481 — genomics — Posted on 2019-03-31

34 Quantitative characterization of random partitioning in the evolution of plasmid-encoded traits

Halleran, A. D.; Flores-Bautista, E.; Murray, R. M.

10.1101/594879 — evolutionary biology — Posted on 2019-03-31

35 Ferrous-glutathione coupling mediates ferroptosis and frailty in Caenorhabditis elegans

Jenkins, N. L.; James, S. A.; Salim, A.; Sumardy, F.; Speed, T. P.; Conrad, M.; Richardson, D. R.; Bush, A. I.; McColl, G.

10.1101/594408 — molecular biology — Posted on 2019-03-31

36 CDK2 kinase activity is a regulator of male germ cell fate

Singh, P.; Patel, R.; Palmer, N.; Grenier, J.; Paduch, D.; Kaldis, P.; Grimson, A.; Schimenti, J.

10.1101/595223 — genetics — Posted on 2019-03-31

37 Latitudinal variation in circadian rhythmicity in Nasonia vitripennis

Paolucci, S.; Dalla Benetta, E.; Salis, L.; Dolezel, D.; van de Zande, L.; Beukeboom, L.

10.1101/594606 — evolutionary biology — Posted on 2019-03-31

38 Functional diversity plays a role in driving β-diversity: Or does it?

Murray-Stoker, D.

10.1101/594044 — ecology — Posted on 2019-03-31

39 Estimation of cell lineage trees by maximum-likelihood phylogenetics

Feng, J.; DeWitt, W. S.; McKenna, A.; Simon, N.; Willis, A. D.; Matsen, F. A.

10.1101/595215 — bioinformatics — Posted on 2019-03-31

40 Behavioural analysis of single-cell aneural ciliate, Stentor roeselii, using machine learning approaches

Trinh, K. M.; Wayland, M.; Prabakaran, S.

10.1101/594796 — animal behavior and cognition — Posted on 2019-03-31

41 Neurocognitive reorganization between crystallized intelligence, fluid intelligence and white matter microstructure in two age-heterogeneous developmental cohorts

Simpson-Kent, I.; Fuhrmann, D.; Bathelt, J.; Achterberg, J.; Borgeest, G. S.; Kievit, R.

10.1101/593509 — neuroscience — Posted on 2019-03-31

42 Complexity measures of the electroencephalograph capture loss and recovery of consciousness in patients anesthetized with propofol

Eagleman, S. L.; Chander, D.; Reynolds, C.; Ouellette, N. T.; MacIver, M. B.

10.1101/594002 — neuroscience — Posted on 2019-03-31

43 Efficacy of antifungal drug combinations against widespread primary resistance, cross-resistance, and multidrug-resistance in Candida auris from New York Hospitals and Healthcare Facilities

O'Brien, B.; Chaturvedi, S.; Chaturvedi, V.

10.1101/593848 — microbiology — Posted on 2019-03-31

44 New non-bilaterian transcriptomes provide novel insights into the evolution of coral skeletomes

Conci, N.; Woerheide, G.; Vargas, S.

10.1101/594242 — evolutionary biology — Posted on 2019-03-31

45 Quantifying shape, integration, and ecology in avian pedal claws: comparing geometric morphometric and traditional metric approaches

Hedrick, B.; Cordero, S.; Zanno, L.; Noto, C.; Dodson, P.

10.1101/593236 — evolutionary biology — Posted on 2019-03-31

46 A comprehensive genome-scale model for Rhodosporidium toruloides IFO0880 accounting for functional genomics and phenotypic data

Dinh, H. V.; Suthers, P. F.; Chan, S. H. J.; Shen, Y.; Xiao, T.; Deewan, A.; Jagtap, S. S.; Rabinowitz, J. D.; Rao, C. V.; Zhao, H.; Maranas, C. D.

10.1101/594846 — systems biology — Posted on 2019-03-31

47 The complex genetic architecture of recombination and structural variation in wheat uncovered using a large 8-founder MAGIC population

Shah, R.; Huang, B. E.; Whan, A.; Newberry, M.; Verbyla, K.; Morell, M. K.; Cavanagh, C. R.

10.1101/594317 — plant biology — Posted on 2019-03-31

48 The origins of anterograde interference in visuomotor adaptation

Lerner, G.; Albert, S.; Caffaro, P. A.; Villalta, J. I.; Jacobacci, F.; Shadmehr, R.; Della-Maggiore, V.

10.1101/593996 — neuroscience — Posted on 2019-03-31

49 A three-sample test for introgression

Hahn, M. W.; Hibbins, M. S.

10.1101/594333 — evolutionary biology — Posted on 2019-03-31

50 Non-uniform Crowding Enhances Transport: Relevance to Biological Environments

Collins, M.; Mohajerani, F.; Ghosh, S.; Guha, R.; Lee, T.-H.; Butler, P. J.; Sen, A.; Velegol, D.

10.1101/593855 — biophysics — Posted on 2019-03-31

51 A vibrating mesh nebulizer as an alternative to the Collison 3-jet nebulizer for infectious disease aerobiology.

Bowling, J. D.; O'Malley, K. J.; Klimstra, W. B.; Hartman, A. L.; Reed, D. S.

10.1101/594358 — microbiology — Posted on 2019-03-31

52 Fitness benefits of a motivated mom

Westrick, S. E.; Taylor, R. W.; Boutin, S.; Lane, J. E.; McAdam, A. G.; Dantzer, B.

10.1101/594093 — evolutionary biology — Posted on 2019-03-31

53 Stability of Nitroxide Biradical TOTAPOL in Biological Samples

McCoy, K. M.; Rogawski, R.; Stovicek, O.; McDermott, A. E.

10.1101/592766 — biophysics — Posted on 2019-03-31

54 STELAR: A statistically consistent coalescent-based species tree estimation method by maximizing triplet consistency

Islam, M.; Sarker, K.; Das, T.; Reaz, R.; Bayzid, M. S.

10.1101/594911 — bioinformatics — Posted on 2019-03-31

55 Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis

Shen, H.; Qu, Z.; Harata-Lee, Y.; Nwe Aung, T.; Cui, J.; Wang, W.; Kortschak, R. D.; Adelson, D. L.

10.1101/592964 — pharmacology and toxicology — Posted on 2019-03-31

56 The impact of sequencing depth on the inferred taxonomic composition and AMR gene content of metagenomic samples

Gweon, H. S.; Shaw, L. P.; Swann, J.; De Maio, N.; AbuOun, M.; Hubbard, A. T. M.; Bowes, M. J.; Bailey, M. J.; Peto, T. E. A.; Hoosdally, S. J.; Walker, A. S.; Sebra, R. P.; Crook, D. W.; Anjum, M.; Read, D. S.; Stoesser, N.; The REHAB consortium,

10.1101/593301 — microbiology — Posted on 2019-03-31

57 A set of Arabidopsis genes involved in the accommodation of the downy mildew pathogen Hyaloperonospora arabidopsidis

Ried, M. K.; Banhara, A.; Binder, A.; Hwu, F.-Y.; Gust, A. A.; Höfle, C.; Huckelhoven, R.; Nuernberger, T.; Parniske, M.

10.1101/286872 — plant biology — Posted on 2019-03-31

58 An axiomatic basis for maximal homology alignment

Erives, A. J.

10.1101/593228 — genetics — Posted on 2019-03-31

59 Inhibition of the Dead Box RNA Helicase 3 prevents HIV-1 Tat and cocaine-induced neurotoxicity by targeting microglia activation

Aksenova, M.; Sybrandt, J.; Cui, B.; Sikirzhytski, V.; Ji, H.; Odhiambo, D.; Lucius, M. D.; Turner, J. R.; Broude, E.; Pena, E.; Lizzaraga, S.; Zhu, J.; Safro, I.; Wyatt, M. D.; Shtutman, M.

10.1101/591438 — neuroscience — Posted on 2019-03-31

60 An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data

Stern, A. J.; Wilton, P. R.; Nielsen, R.

10.1101/592675 — genetics — Posted on 2019-03-31

61 Gene expression profiles and pathway enrichment analysis to identification of differentially expressed gene and signaling pathways in epithelial ovarian cancer based on high-throughput RNA-seq data

Siavoshi, A.; Taghizadeh, M.; Dookhe, E.; Piran, M.

10.1101/566331 — genomics — Posted on 2019-03-31

62 Ribosome profiling at isoform level reveals an evolutionary conserved impact of differential splicing on the proteome

Reixachs-Sole, M.; Ruiz-Orera, J.; Alba, M. M.; Eyras, E.

10.1101/582031 — genomics — Posted on 2019-03-31

63 A non-canonical role and regulations of polo-like kinase-4 in fibroblast cell-type transition

Li, J.; Urabe, G.; Zhang, M.; Huang, Y.; Wang, B.; Marcho, L.; Shen, H.; Kent, K. C.; Guo, L.-W.

10.1101/570267 — cell biology — Posted on 2019-03-31

64 Translating antibiotic prescribing into antimicrobial resistance in the environment: a hazard characterisation case study

Singer, A. C.; Xu, Q.; Keller, V. D.

10.1101/539536 — microbiology — Posted on 2019-03-31

65 The international sinonasal microbiome study (ISMS): a multi-centre, multi-national collaboration characterising the microbial ecology of the sinonasal cavity

Paramasivan, S.; Bassiouni, A.; Shiffer, A.; Dillon, M. R.; Cope, E. K.; Cooksley, C.; Ramezanpour, M.; Moraitis, S.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J.

10.1101/548743 — microbiology — Posted on 2019-03-31

66 Microbiotyping the sinonasal microbiome

Bassiouni, A.; Paramasivan, S.; Shiffer, A.; Dillon, M. R.; Cope, E. K.; Cooksley, C.; Ramezanpour, M.; Moraitis, S.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J.

10.1101/549311 — microbiology — Posted on 2019-03-31

67 Perceptron learning and classification in a modeled cortical pyramidal cell

Moldwin, T.; Segev, I.

10.1101/464826 — neuroscience — Posted on 2019-03-31

68 The development, recognition, and learning mechanisms of an animal-like neural network

Qi, F.; Wu, W.

10.1101/535724 — neuroscience — Posted on 2019-03-31

69 Genetic insights into the social organisation of the Avar period elite in the 7th century AD Carpathian Basin

Csaky, V.; Gerber, D.; Koncz, I.; Csiky, G.; Mende, B. G.; Szeifert, B.; Egyed, B.; Pamjav, H.; Marcsik, A.; Molnar, E.; Palfi, G.; Gulyas, A.; Kovacsoczy, B.; Lezsak, G. M.; Lorinczy, G.; Szecsenyi-Nagy, A.; Vida, T.

10.1101/415760 — genetics — Posted on 2019-03-31

70 Repurposing the biased visibility in HiC datasets to mark dynamically regulated condensed and decondensed chromatin states genome-wide.

Chandradoss, K. R.; Guthikonda, P. K.; Kethavath, S.; Dass, M.; Singh, H.; Nayak, R.; Kurukuti, S.; Sandhu, K. S.

10.1101/498006 — genomics — Posted on 2019-03-31

71 Perceptron learning and classification in a modeled cortical pyramidal cell

Moldwin, T.; Segev, I.

10.1101/464826 — neuroscience — Posted on 2019-03-31

72 Patterns of fish utilisation in a tropical Indo-Pacific mangrove-coral seascape, New Caledonia

Dubuc, A.; Waltham, N.; Baker, R.; Marchand, C.; Sheaves, M.

10.1101/455931 — ecology — Posted on 2019-03-31

73 Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection of cancer

Ulz, P.; Perakis, S.; Zhou, Q.; Moser, T.; Belic, J.; Lazzeri, I.; Wölfler, A.; Zebisch, A.; Gerger, A.; Pristauz, G.; Petru, E.; White, B.; Roberts, C. E. S.; St. John, J.; Schimek, M. G.; Geigl, J. B.; Bauernhofer, T.; Sill, H.; Bock, C.; Heitzer, E.; Speicher, M. R.

10.1101/456681 — cancer biology — Posted on 2019-03-31

74 SNPs associated with HHIP expression have differential effects on lung function in males and females

Fawcett, K.; Obeidat, M.; Melbourne, C. A.; Shrine, N.; Guyatt, A. L.; John, C.; Luan, J.; Richmond, A.; Moksnes, M. R.; Granell, R.; Weiss, S.; Imboden, M.; May-Wilson, S.; Hysi, P.; Boutin, T. S.; Portas, L.; Flexeder, C.; Harris, S. E.; Wang, C. A.; Lyytikainen, L.-P.; Palviainen, T.; Foong, R. E.; Keidel, D.; Minelli, C.; Langenberg, C.; Bosse, Y.; van den Berge, M.; Sin, D. D.; Hao, K.; Campbell, A.; Porteous, D.; Padmanabhan, S.; Smith, B. H.; Evans, D.; Ring, S.; Langhammer, A.; Hveem, K.; Willer, C.; Ewert, R.; Stubbe, B.; Pirastu, N.; Klaric, L.; Joshi, P. K.; Patasova, K.; Massimo, M

10.1101/594457 — genetics — Posted on 2019-03-31

75 Rho-mediated gene transcription promotes BRAF inhibitor resistance in de-differentiated melanoma cells

Misek, S. A.; Appleton, K. M.; Dexheimer, T. S.; Lisabeth, E. M.; Lo, R.; Larsen, S. D.; Gallo, K.; Neubig, R. R.

10.1101/381806 — cancer biology — Posted on 2019-03-31

76 A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

Emdin, C. A.; Haas, M.; Khera, A. V.; Aragam, K.; Chaffin, M.; Jiang, L.; Wei, W.-Q.; Feng, Q.; Karjalainen, J.; Havulinna, A.; Kiiskinen, T.; Bick, A.; Ardissino, D.; Wilson, J. G.; Schunkert, H.; McPherson, R.; Watkins, H.; Elosua, R.; Bown, M. J.; Samani, N. J.; Baber, U.; Erdmann, J.; Gupta, N.; Danesh, J.; Saleheen, D.; Daly, M.; Denny, J.; Gabriel, S.; Kathiresan, S.

10.1101/594523 — genomics — Posted on 2019-03-31

77 Opposing contributions of GABAergic and glutamatergic ventral pallidal neurons to motivational behaviours

Stephenson-Jones, M.; Bravo-Rivera, C.; Ahrens, S.; Furlan, A.; Fernandes-Henriques, C.; Li, B.

10.1101/594887 — neuroscience — Posted on 2019-03-31

78 Two molecules of Has1 RNA helicase function simultaneously in the biogenesis of small and large ribosomal subunits

Gnanasundram, S. V.; Kos-Braun, I. C.; Kos, M.

10.1101/594762 — molecular biology — Posted on 2019-03-31

79 Tracking microbial evolution in the human gut using Hi-C

Relman, D. A.; Yaffe, E.

10.1101/594903 — microbiology — Posted on 2019-03-31

80 Dual-matrix 3D culture system as a biomimetic model of epithelial tissues

Bogorodskaya, D.; McLane, J. S.; Ligon, L. A.

10.1101/594549 — cell biology — Posted on 2019-03-31

81 Exploring Structural Aspects of the Human Golgi Matrix Protein GRASP55 in Solution

Reddy, S. T.; Mendes, L. F. S.; Fontana, N. A.; Costa-Filho, A. J.

10.1101/594572 — biophysics — Posted on 2019-03-31

82 Axonal transport of an insulin-like peptide mRNA promotes stress recovery in C. elegans

Chandra, R.; Li, L.; Husain, Z.; Mishra, S.; Alcedo, J.

10.1101/594689 — neuroscience — Posted on 2019-03-31

83 Acute decrease in plasma membrane tension induces macropinocytosis via PLD2 activation

Loh, J.; Joseph, J.; Chuang, M.-C.; Lin, S.-S.; Chang, Y.-C.; Su, Y.-A.; Liu, A. P.; Liu, Y.-W.

10.1101/594416 — cell biology — Posted on 2019-03-31

84 Septins Coordinate with Microtubules and Actin to Initiate Cell Morphogenesis

Bogorodskaya, D.; Ligon, L. A.

10.1101/594515 — cell biology — Posted on 2019-03-31

85 A Ssd1 homolog impacts trehalose and chitin biosynthesis and contributes to virulence in Aspergillus fumigatus

Thammahong, A.; Dhingra, S.; Bultman, K. M.; Kerkaert, J. D.; Cramer, R. A.

10.1101/594341 — microbiology — Posted on 2019-03-31

86 First-principles prediction of the information processing capacity of a simple genetic circuit

Razo-Mejia, M.; Phillips, R.

10.1101/594325 — biophysics — Posted on 2019-03-31

87 A novel phyllosphere resident Protomyces species that interacts with the Arabidopsis immune system.

Wang, K.; Sipilä, T.; Rajaraman, S.; Safronov, O.; Laine, P.; Auzane, A.; Mari, A.; Auvinen, P.; Paulin, L.; Kemen, E.; Salojärvi, J.; Overmyer, K.

10.1101/594028 — microbiology — Posted on 2019-03-31

88 BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila

Ueberschar, M.; Wang, H.; Zhang, C.; Guo, E.; Lai, E.; Wen, J.; Dai, Q.

10.1101/593830 — developmental biology — Posted on 2019-03-31

89 Pre-Settlement Forest around Puget Sound: Eyewitness Evidence

Schroeder, T.

10.1101/592733 — plant biology — Posted on 2019-03-31

90 Understanding multivariate brain activity: evaluating the effect of voxelwise noise correlations on population codes in functional magnetic resonance imaging

Zhang, R.-Y.; Wei, X.-X.; Kay, K.

10.1101/592618 — neuroscience — Posted on 2019-03-31

91 Transcriptional maintenance of cortical somatostatin interneuron subtype identity during migration

Munguba, H.; Nikouei, K.; Hochgerner, H.; Oberst, P.; Kouznetsova, A.; Ryge, J.; Bastista-Brito, R.; Munoz-Manchado, A. B.; Close, J.; Linnarsson, S.; Hjerling Leffler, J.

10.1101/593285 — neuroscience — Posted on 2019-03-31

92 Microsaccades and attention in a high-acuity visual alignment task.

Nanjappa, R. K.; McPeek, R. M.

10.1101/592709 — neuroscience — Posted on 2019-03-31

93 Beta rhythm events predict corticospinal motor output

Boenstrup, M.; Cohen, L. G.; Hussain, S. J.

10.1101/588632 — neuroscience — Posted on 2019-03-31

94 PLANT NATRIURETIC PEPTIDE A antagonizes salicylic acid-primed cell death

Lee, K. P.; Liu, K.; Kim, E. Y.; Medina-Puche, L.; Duan, J.; Li, Y.; Dong, H.; Lv, R.; Li, Z.; Lozano-Duran, R.; Kim, C.

10.1101/592881 — plant biology — Posted on 2019-03-31

95 Sex Differences in Head-fixed Running Behavior

Warner, E. J.; Padmanabhan, K.

10.1101/585000 — neuroscience — Posted on 2019-03-31

96 Coordinating Receptor Expression and Wiring Specificity in Olfactory Receptor Neurons

Li, H.; Li, T.; Horns, F.; Li, J.; Xie, Q.; Xu, C.; Wu, B.; Kebschull, J.; Vacek, D.; Xie, A.; Luginbuhl, D.; Quake, S.; Luo, L.

10.1101/594895 — neuroscience — Posted on 2019-03-31

97 Macrophage-mediated immunoediting drives ductal carcinoma evolution: Space is the game changer

Gatenbee, C.; West, J.; Baker, A. M.; Guljar, N.; Jones, L.; Graham, T. A.; Robertson-Tessi, M.; Anderson, A. R.

10.1101/594598 — cancer biology — Posted on 2019-03-31

98 The mutational landscape of a prion-like domain

Bolognesi, B. M.; Faure, A. J.; Seuma, M.; Schmiedel, J. M.; Tartaglia, G.; Lehner, B.

10.1101/592121 — genetics — Posted on 2019-03-31

99 Modern clinical Mtb strains leverage the type I IFN pathway for a pro-inflammatory response in the host

Shankaran, D.; Arumugam, P.; Gandotra, S.; Rao, V. K.

10.1101/594655 — immunology — Posted on 2019-03-31

100 CRISPR-Cas9 Gene Editing in Lizards Through Microinjection of Unfertilized Oocytes

Rasys, A. M.; Park, S.; Ball, R. E.; Alcala, A. J.; Lauderdale, J. D.; Menke, D. B.

10.1101/591446 — genetics — Posted on 2019-03-31

101 Constitutive IRE1α signaling maintains glioblastoma cell differentiation

Doultsinos, D.; McMahon, M.; Voutetakis, K.; Obacz, J.; Pineau, R.; Jouan, F.; Le Reste, P.-J.; Obiedat, A.; Samal, J.; Patterson, J. B.; Zheng, Q.; Samali, A.; Pandit, A.; Tirosh, B.; Chatziioannou, A.; Chevet, E.; Avril, T.

10.1101/594630 — cancer biology — Posted on 2019-03-31

102 Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

Byrne, E. M.; Zhu, Z.; Qi, T.; Skene, N. G.; Bryois, J.; Pardinas, A. F.; Stahl, E.; Smoller, J. W.; Rietschel, M.; Bipolar Working Group of the Psychiatric Genomics Consortium, ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Owen, M. J.; Walters, J. T. R.; ODonovan, M. C.; McGrath, J. G.; Hjerling-Leffler, J.; Sullivan, P. F.; Goddard, M. E.; Visscher, P. M.; Yang, J.; Wray, N. R.

10.1101/592899 — genetics — Posted on 2019-03-31

103 Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

Howe, L. J.; Lawson, D. J.; Davies, N. M.; Pourcain, B. S.; Lewis, S. J.; Smith, G. D.; Hemani, G.

10.1101/418269 — genetics — Posted on 2019-03-31

104 Relative performance of Oxford Nanopore MinION vs. Pacific Biosciences Sequel third-generation sequencing platforms in identification of agricultural and forest pathogens

Loit, K.; Adamson, K.; Bahram, M.; Puusepp, R.; Anslan, S.; Kiiker, R.; Drenkhan, R.; Tedersoo, L.

10.1101/592972 — microbiology — Posted on 2019-03-30

105 Characterising antibody kinetics from multiple influenza infection and vaccination events in ferrets

Hay, J. A.; Laurie, K.; White, M.; Riley, S.

10.1101/411751 — immunology — Posted on 2019-03-30

106 Intergenerational effects of early adversity on survival in wild baboons

Zipple, M. N.; Archie, E. A.; Tung, J.; Altmann, J.; Alberts, S. C.

10.1101/591248 — zoology — Posted on 2019-03-30

107 Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design

Rokita, J. L.; Rathi, K. S.; Cardenas, M. F.; Upton, K. A.; Jayaseelan, J.; Cross, K. L.; Pfeil, J.; Ritenour, L. E.; Modi, A.; Farrel, A.; Way, G. P.; Kendsersky, N. M.; Patel, K.; Lopez, G.; Vaksman, Z.; Mayoh, C.; Nance, J.; McCoy, K.; Haber, M.; Evans, K.; McCalmont, H.; Bendak, K.; Bohm, J. W.; Marshall, G. M.; Tyrrell, V.; Kalletla, K.; Braun, F. K.; Qi, L.; Du, Y.; Zhang, H.; Lindsay, H. B.; Zhao, S.; Shu, J.; Baxter, P.; Morton, C.; Kurmashev, D.; Zheng, S.; Chen, Y.; Bowen, J.; Bryan, A. C.; Leraas, K. M.; Coppens, S. E.; Doddapaneni, H.; Momin, Z.; Zhang, W.; Sacks, G. I.; Hart, L. S

10.1101/566455 — genomics — Posted on 2019-03-30

108 Functional genomics of a symbiotic community: shared traits in the olive fruit fly gut microbiota

Blow, F.; Gioti, A.; Goodhead, I. B.; Kalyva, M.; Kampouraki, A.; Vontas, J.; Darby, A. C.

10.1101/590489 — evolutionary biology — Posted on 2019-03-30

109 Differential Expression of N- and O-glycans on HeLa Cells -Revealed by Direct Fluorescent Glycan Labeling with Recombinant Sialyltransferases

Wu, Z.; Person, A. D.; Burton, A. J.; Singh, R.; Burroughs, B.; Fryxell, D.; Tatge, T. J.; Manning, T.; Wu, G.; Swift, K.; Kalabokis, V.

10.1101/580571 — cell biology — Posted on 2019-03-30

110 Reducing variability in along-tract analysis with diffusion profile realignment

St-Jean, S.; Chamberland, M.; Viergever, M. A.; Leemans, A.

10.1101/541920 — neuroscience — Posted on 2019-03-30

111 UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy

Seaborne, R. A.; Hughes, D. C.; Turner, D. C.; Owens, D. J.; Baehr, L. M.; Gorski, P.; Semenova, E. A.; Borisov, O. V.; Larin, A. K.; Popov, D. V.; Generozov, E. V.; Sutherland, H.; Ahmetov, I. I.; Jarvis, J. C.; Bodine, S. C.; Sharples, A. P.

10.1101/592980 — physiology — Posted on 2019-03-30

112 Parsimonious scenario for the emergence of viroid-like replicons de novo

Catalan, P.; Elena, S. F.; Cuesta, J. A.; Manrubia, S.

10.1101/593640 — evolutionary biology — Posted on 2019-03-30

113 Differences in player position running velocity at lactate thresholds among male professional German soccer players

Schwesig, R.; Schulze, S.; Reinhardt, L.; Delank, K.-S.; Laudner, K. G.; Hermassi, S.

10.1101/592188 — physiology — Posted on 2019-03-30

114 Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and - independent phagosomal signals that contribute to phagocytosis and inflammation

Benjamin, S. J.; Hawley, K. L.; Vera-Licona, M. P.; LaVake, C. J.; Cervantes, J. L.; Burns, R.; Luo, O.; Ruan, Y.; Caimano, M.; Radolf, J. D.; Salazar, J. C.

10.1101/593566 — immunology — Posted on 2019-03-30

115 A Comparative Assessment of Visceral Leishmaniasis Burden in Two Eco-epidemiologically Different Countries, India and Sudan

Mubayi, A.; Barley, K.; Safan, M.; Castillo-Chavez, C.

10.1101/592220 — epidemiology — Posted on 2019-03-30

116 Environmental light is required for maintenance of long-term memory in Drosophila

Inami, S.; Sato, S.; Kondo, S.; Tanimoto, H.; Kitamoto, T.; Sakai, T.

10.1101/592667 — neuroscience — Posted on 2019-03-30

117 Flat Electrode Contacts for Peripheral Nerve Stimulation

Bucksot, J.; Wells, A. J.; Rahebi, K. C.; Sivaji, V.; Romero-Ortega, M.; Kilgard, M. P.; Rennaker, R. L.; Hays, S. A.

10.1101/593467 — bioengineering — Posted on 2019-03-30

118 Epithelial micro-invasion by Streptococcus pneumoniae induces epithelial-derived innate immunity during colonisation at the human mucosal surface

Weight, C. M.; Venturini, C.; Pojar, S.; Jochems, S.; Reine, J.; Nikolaou, E.; Solorzano, C.; Noursadeghi, M.; Brown, J. S.; Ferreira, D. M.; Heyderman, R. S.

10.1101/281576 — immunology — Posted on 2019-03-30

119 Euplotid: A quantized geometric model of the eukaryotic cell

Borges-Rivera, D.

10.1101/170159 — biophysics — Posted on 2019-03-30

120 State-dependent geometry of population activity in rat auditory cortex

Kobak, D.; Pardo-Vazquez, J. L.; Valente, M.; Machens, C.; Renart, A.

10.1101/501338 — neuroscience — Posted on 2019-03-30

121 TDP-43 proteinopathy impairs neuronal mRNP granule mediated postsynaptic local translation and mRNA metabolism

Wong, C.-E.; Tsai, K.-J.

10.1101/589416 — neuroscience — Posted on 2019-03-30

122 Increased molecular plasticity along the septotemporal axis of the hippocampus is associated with network functioning.

Sotiriou, E.; Angelatou, F.; Papatheodoropoulos, C.

10.1101/593095 — neuroscience — Posted on 2019-03-30

123 Synaptotagmin 1 oligomers clamp and regulate different modes of neurotransmitter release

Tagliatti, E.; Bello, O. D.; Mendonca, P. R. F.; Kotzadimitriou, D.; Nicholson, E.; Coleman, J.; Timofeeva, Y.; Rothman, J.; Krishnakumar, S.; Volynski, K.

10.1101/594051 — neuroscience — Posted on 2019-03-30

124 Patterns and potential drivers of intraspecific variability in the body elemental composition of a terrestrial consumer, the snowshoe hare (Lepus americanus)

Rizzuto, M.; Leroux, S. J.; Vander Wal, E.; Wiersma, Y. F.; Heckford, T. R.; Balluffi-Fry, J.

10.1101/594101 — ecology — Posted on 2019-03-30

125 High-Speed Automatic Characterization of Rare Events in Flow Cytometric Data

Qi, Y.; Fang, Y.; Sinclair, D. R.; Guo, S.; Alberich-Jorda, M.; Lu, J.; Tenen, D. G.; Kharas, M. G.; Pyne, S.

10.1101/591644 — bioinformatics — Posted on 2019-03-30

126 Immortalization of different breast epithelial cell types results in distinct mitochondrial mutagenesis

Kwon, S.; Kim, S.; Nebeck, H.; Ahn, E. H.

10.1101/592832 — genomics — Posted on 2019-03-30

127 Estimating the sensitivity of associations between risk factors and outcomes to shared genetic effects

Pingault, J.-B.; Rijsdijk, F.; Schoeler, T.; Choi, S. W.; Selzam, S.; Krapohl, E.; O'Reilly, P. F.; Dudbridge, F.

10.1101/592352 — genetics — Posted on 2019-03-30

128 Transposable temperate phages promote the evolution of divergent social strategies in Pseudomonas aeruginosa populations

O'Brien, S.; Kummerli, R.; Paterson, S.; Winstanley, C.; Brockhurst, M. A.

10.1101/593798 — evolutionary biology — Posted on 2019-03-30

129 Spatiotemporal Dynamics of Stream Fish Assemblages Over Four Decades

Zbinden, Z. D.

10.1101/592469 — ecology — Posted on 2019-03-30

130 Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation

Cerqueira Campos, F.; Alegot, H.; Dennis, C.; Fritsch, C.; Isabella, A.; Pouchin, P.; Bardot, O.; Horne-Badovinac, S.; Mirouse, V.

10.1101/591628 — developmental biology — Posted on 2019-03-30

131 Convergent genes shape budding yeast pericentromeres

Paldi, F.; Alver, B.; Robertson, D.; Schalbetter, S. A.; Kerr, A.; Kelly, D. A.; Neale, M. J.; Baxter, J.; Marston, A.

10.1101/592782 — cell biology — Posted on 2019-03-30

132 FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

Diaz Osterman, C. J.; Ozmadenci, D.; Kleinschmidt, E. G.; Taylor, K. N.; Barrie, A. M.; Jiang, S.; Bean, L. M.; Sulzmaier, F. J.; Jean, C.; Tancioni, I.; Anderson, K.; Uryu, S.; Cordasco, E. A.; Li, J.; Chen, X. L.; Fu, G.; Ojalill, M.; Rappu, P.; Heino, J.; Mark, A. M.; Xu, G.; Fisch, K. M.; Kolev, V. N.; Weaver, D. T.; Pachter, J. A.; Gyorffy, B.; McHale, M. T.; Connolly, D. C.; Molinolo, A.; Stupack, D. G.; Schlaepfer, D. D.

10.1101/594184 — cancer biology — Posted on 2019-03-30

133 DeepSSV: detecting somatic small variants in paired tumor and normal sequencing data with convolutional neural network

Meng, J.; Victor, B.; He, Z.; Salim, A.

10.1101/555680 — bioinformatics — Posted on 2019-03-30

134 Ultrasound- and microbubble-mediated targeted delivery of therapeutic microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs

di Ianni, T.; Bose, R. J. C.; Sukumar, U. K.; Bachawal, S.; Wang, H.; Telichko, A.; Herickhoff, C. D.; Robinson, E.; Baker, S.; Vilches-Moure, J. G.; Felt, S. A.; Gambhir, S. S.; Paulmurugan, R.; Dahl, J. D.

10.1101/592931 — bioengineering — Posted on 2019-03-30

135 Initiation of chromosome replication controls both division and replication cycles in E. coli through a double-adder mechanism

Witz, G.; van Nimwegen, E. J.; Julou, T.

10.1101/593590 — systems biology — Posted on 2019-03-30

136 Deep learning-based imaging classification identified cingulate island sign in dementia with Lewy bodies

Iizuka, T.; Fukasawa, M.; Kameyama, M.

10.1101/592865 — neuroscience — Posted on 2019-03-30

137 Differences in sodium channel densities in the apical dendrites of pyramidal cells of the electrosensory lateral line lobe.

Motipally, S. I.; Allen, K. M.; Williamson, D. K.; Marsat, G.

10.1101/592758 — neuroscience — Posted on 2019-03-30

138 Feature overlap modulates rapid semantic but not lexical integration of novel associations by means of fast mapping

Zaiser, A.-K.; Meyer, P.; Bader, R.

10.1101/594218 — neuroscience — Posted on 2019-03-30

139 Chronic corticosterone administration induces negative valence and impairs positive valence behaviors in mice

Dieterich, A.; Srivastava, P.; Sharif, A.; Stech, K.; Samuels, B. A.

10.1101/593632 — neuroscience — Posted on 2019-03-30

140 Co-occurrence of multiple CRISPRs and cas clusters suggests epistatic interactions

Bernheim, A.; Bikard, D.; Touchon, m.; Rocha, E.

10.1101/592600 — genomics — Posted on 2019-03-30

141 Multi-Trait Improvement by Predicting Genetic Correlations in Breeding Crosses

Neyhart, J.; Lorenz, A. J.; Smith, K. P.

10.1101/593210 — genetics — Posted on 2019-03-30

142 Whole genome duplication potentiates inter-specific hybridisation and niche shifts in Australian burrowing frogs Neobatrachus

Novikova, P. Y.; Brennan, I. G.; Booker, W.; Mahony, M.; Doughty, P.; Lemmon, A. R.; Lemmon, E. M.; Yant, L.; Van de Peer, Y.; Keogh, J. S.; Donnellan, S. C.

10.1101/593699 — evolutionary biology — Posted on 2019-03-30

143 Population fragmentation leads to morpho-functional variation in British red squirrels (Sciurus vulgaris)

Cox, P. G.; Morris, P. J.; Kitchener, A. C.

10.1101/593319 — evolutionary biology — Posted on 2019-03-30

144 Pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers

Boyle, C. J.; Higgins, C. A.; Masen, M. A.; Masouros, S. D.

10.1101/592477 — bioengineering — Posted on 2019-03-30

145 Ligands, receptors and transcription factors that mediate inter-cellular and intra-cellular communication during ovarian follicle development

Penalver Bernabe, B.; Woodruff, T.; Broadbelt, L.; Shea, L.

10.1101/594234 — systems biology — Posted on 2019-03-30

146 A toolset of constitutive promoters for metabolic engineering of Rhodosporidium toruloides

Nora, L. C.; Wehrs, M.; Kim, J.; Cheng, J.-F.; Tarver, A.; Simmons, B. A.; Magnuson, J.; Harmon-Smith, M.; Silva-Rocha, R.; Gladden, J. M.; Mukhopadhyay, A.; Skerker, J. M.; Kirby, J.

10.1101/592774 — synthetic biology — Posted on 2019-03-30

147 MARGO (Massively Automated Real-time GUI for Object-tracking), a platform for high-throughput ethology

Werkhoven, Z.; Rohrsen, C.; Qin, C.; Brembs, B.; de Bivort, B. L.

10.1101/593046 — neuroscience — Posted on 2019-03-30

148 ezTrack: An open-source video analysis pipeline for the investigation of animal behavior

Pennington, Z. T.; Dong, Z.; Bowler, R.; Feng, Y.; Vetere, L. M.; Shuman, T.; Cai, D. J.

10.1101/592592 — neuroscience — Posted on 2019-03-30

149 Analysis of miniaturization effects and channel selection strategies for EEG sensor networks with application to auditory attention detection

Mundanad Narayanan, A.; Bertrand, A.

10.1101/593194 — neuroscience — Posted on 2019-03-30

150 Opposing chromatin remodelers control transcription initiation frequency and start site selection

Kubik, S.; Challal, D.; Bruzzone, M. J.; Dreos, R.; Mattarocci, S.; Bucher, P.; Libri, D.; Shore, D.

10.1101/592816 — molecular biology — Posted on 2019-03-30

151 Prokaryotic SPHINX sequences are conserved in mammalian brain and participate in neurodegeneration

Manuelidis, L.; Szigeti-Buck, K.

10.1101/593954 — evolutionary biology — Posted on 2019-03-30

152 Drivers of amphibian population dynamics and asynchrony at local and continental scales

Cayuela, H.; Griffiths, R. A.; Zakaria, N.; Arntzen, J. W.; Priol, P.; Lena, J.-P.; Besnard, A.; Joly, P.

10.1101/592683 — ecology — Posted on 2019-03-30

153 Severely stressful natal environment does not impact lifetime reproductive success of adult boobies

Ortega, S.; Rodriguez, C.; Drummond, H.

10.1101/594226 — ecology — Posted on 2019-03-30

154 A Bile Duct-on-a-Chip with Organ-Level Functions

Du, Y.; Khandekar, G.; Llewellyn, J.; Polacheck, W.; Chen, C. S.; Wells, R. G.

10.1101/594291 — bioengineering — Posted on 2019-03-30

155 Crosstalk and Ultrasensitivity in Protein Degradation Pathways

Mallela, A.; Nariya, M. K.; Deeds, E. J.

10.1101/594085 — systems biology — Posted on 2019-03-30

156 Differential impacts of the head on Platynereis dumerilii peripheral circadian rhythms

Arboleda, E.; Zurl, M.; Tessmar-Raible, K.

10.1101/593772 — physiology — Posted on 2019-03-30

157 A new strategy for identifying mechanisms of drug-drug interaction using transcriptome analysis: Compound Kushen injection as a proof of principle

Shen, H. Y.; Qu, Z.; Harata-Lee, Y.; Cui, J.; Nwe Aung, T.; Wang, W.; Kortschak, R. D.; Adelson, D. L.

10.1101/592956 — pharmacology and toxicology — Posted on 2019-03-30

158 PhenoMS-ML: Phenotypic Screening by Mass Spectrometry and Machine Learning

van Oosten, L. N.; Klein, C. D.

10.1101/593244 — pharmacology and toxicology — Posted on 2019-03-30

159 Mitochondrial dynamics and mitophagy are necessary for proper invasive growth in Rice Blast

Kou, Y.; He, Y.; Qiu, J.; Shu, Y.; Yang, F.; Deng, Y.; Naqvi, N. I.

10.1101/592915 — pathology — Posted on 2019-03-30

160 Cell-type and region-specific nucleus accumbens AMPAR plasticity associated with morphine reward, reinstatement, and spontaneous withdrawal

Madayag, A.; Gomez, D.; Anderson, E.; Ingebretson, A.; Thomas, M.; Hearing, M.

10.1101/592519 — neuroscience — Posted on 2019-03-30

161 Relationship between faecal microbiota and plasma metabolome in rats fed NK603 and MON810 GM maize from the GMO90+ study

Mesnage, R.; Le Roy, C.; Biserni, M.; Salles, B.; Antoniou, M. N.

10.1101/593343 — molecular biology — Posted on 2019-03-30

162 Cutibacterium acnes antibiotic production shapes niche competition in the human skin microbiome

Claesen, J.; Spagnolo, J. B.; Flores Ramos, S.; Kurita, K. L.; Byrd, A. L.; Aksenov, A. A.; Melnik, A. V.; Wong, W. R.; Wang, S.; Hernandez, R. D.; Donia, M. S.; Dorrestein, P. C.; Kong, H. H.; Segre, J. A.; Linington, R. G.; Fischbach, M. A.; Lemon, K. P.

10.1101/594010 — microbiology — Posted on 2019-03-30

163 Controlling Heterogeneity and Increasing Titer from Riboswitch-Regulated Bacillus subtilis Spores for Time-Delayed Protein Expression Applications

Tamiev, D.; Lantz, A.; Vezeau, G.; Salis, H.; Reuel, N.

10.1101/592659 — microbiology — Posted on 2019-03-30

164 Common DNA sequence variation influences 3-dimensional conformation of the human genome

Gorkin, D.; Qiu, Y.; Hu, M.; Fletez-Brant, K.; Liu, T.; Schmitt, A.; Noor, A.; Chiou, J.; Gaulton, K.; Sebat, J.; Li, Y.; Hansen, K.; Ren, B.

10.1101/592741 — genomics — Posted on 2019-03-30

165 Antagonistic coevolution between hosts and sexually transmitted infections

Ashby, B.

10.1101/590232 — evolutionary biology — Posted on 2019-03-30

166 Single Nucleotide Mapping of the Locally Accessible Trait Space in Yeast Reveals Pareto Fronts that Constrain Initial Adaptation

Li, Y.; Petrov, D.; Sherlock, G.

10.1101/593947 — evolutionary biology — Posted on 2019-03-30

167 FIND: Identifying Functionally and Structurally Important Features in Protein Sequences with Deep Neural Networks

Murali, R.; Hemp, J.; Orphan, V.; Bisk, Y.

10.1101/592808 — bioinformatics — Posted on 2019-03-30

168 RNase H1 and H2 are differentially regulated to eliminate RNA-DNA hybrids

Lockhart, A.; Pires, V.; Bento, F.; Kellner, V.; Luke-Glaser, S.; Luke, B.

10.1101/593152 — molecular biology — Posted on 2019-03-30

169 An essential RNA-binding lysine residue in the Nab3 RRM domain undergoes mono and tri-methylation

Lee, K. Y.; Chopra, A.; Biggar, K. K.; Meneghini, M.

10.1101/592923 — molecular biology — Posted on 2019-03-30

170 Detection of Spacer Precursors Formed In Vivo During Primed CRISPR Adaptation

Shiriaeva, A. A.; Savitskaya, E.; Datsenko, K. A.; Vvedenskaya, I. O.; Fedorova, I.; Morozova, N.; Metlitskaya, A.; Sabantsev, A.; Nickels, B. E.; Severinov, K.; Semenova, E.

10.1101/594259 — microbiology — Posted on 2019-03-30

171 CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats

Patel, D. K.; Patel, M.; Singh, U.

10.1101/593137 — genomics — Posted on 2019-03-30

172 Single- nuclei RNA sequencing from human brain to study for Mendelian and sporadic AD

Del-Aguila, J. L.; Li, Z.; Dube, U.; Mihindukulasuriya, K. A.; Budde, J. P.; Fernandez, M. V.; Ibanez, L.; Bradley, J.; Wang, F.; Bergmann, K.; Davenport, R.; Morris, J. C.; Holtzman, D. M.; Perrin, R. J.; Benitez, B. A.; Dougherty, J.; Cruchaga, C.; Harari, O.

10.1101/593756 — genomics — Posted on 2019-03-30

173 An axiomatic basis for maximal homology alignment

Erives, A. J.

10.1101/593228 — genetics — Posted on 2019-03-30

174 Cohesin disrupts polycomb-dependent chromosome interactions

Rhodes, J.; Feldmann, A.; Hernandez-Rodriguez, B.; Diaz, N.; Brown, J.; Fursova, N.; Blackledge, N.; Prathapan, P.; Dobrinic, P.; Huseyin, M.; Szczurek, A.; Kruse, K.; Nasmyth, K.; Buckle, V.; Vaquerizas, J. M.; Klose, R.

10.1101/593970 — genetics — Posted on 2019-03-30

175 Urban ecology of arboviral mosquito vectors along the Kenyan coast

Karisa, J. K.; Muriu, S.; Omuoyo, D.; Karia, B.; Nyamwaya, D.; Rono, M.; Warimwe, G.; Mwangangi, J.; Mbogo, C.

10.1101/593350 — ecology — Posted on 2019-03-30

176 Just how big is intraspecific trait variation in fungal fruit bodies?

Dawson, S. K.; Jonsson, M.

10.1101/593517 — ecology — Posted on 2019-03-30

177 High-throughput quantitative detection of basal autophagy and autophagic flux using image cytometry

Senthilkumar, G.; Skiba, J. H.; Kimple, R.

10.1101/590513 — cell biology — Posted on 2019-03-30

178 Connectivity Measures for Signaling Pathway Topologies

Franzese, N.; Groce, A.; Murali, T. M.; Ritz, A.

10.1101/593913 — bioinformatics — Posted on 2019-03-30

179 Augmented Interval List: a novel data structure for efficient genomic interval search

Feng, J.; Ratan, A.; Sheffield, N.

10.1101/593657 — bioinformatics — Posted on 2019-03-30

180 SCOPE: a normalization and copy number estimation method for single-cell DNA sequencing

Wang, R.; Lin, D.-Y.; Jiang, Y.

10.1101/594267 — bioinformatics — Posted on 2019-03-30

181 Patient-specific haemodynamic simulations of complex aortic dissections informed by commonly available clinical datasets

Bonfanti, M.; Franzetti, G.; Maritati, G.; Homer-Vanniasinkam, S.; Balabani, S.; Diaz-Zuccarini, V.

10.1101/593780 — bioengineering — Posted on 2019-03-30

182 Pat1 activates late steps in mRNA decay by multiple mechanisms

Lobel, J. H.; Tibble, R. W.; Gross, J. D.

10.1101/594168 — biochemistry — Posted on 2019-03-30

183 Two gut microbes are necessary and sufficient for normal cognition in Drosophila melanogaster

DeNieu, M.; Mounts, K.; Manier, M.

10.1101/593723 — animal behavior and cognition — Posted on 2019-03-30

184 A library of cell-surface and secreted proteins from Schistosoma mansoni identifies early serological markers of infection

Crosnier, C.; Protasio, A. V.; Rinaldi, G.; Wilson, S.; Berriman, M.; Wright, G. J.

10.1101/593616 — immunology — Posted on 2019-03-30

185 Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

Byrne, E.; Zhu, Z.; Qi, T.; Skene, N.; Bryois, J.; Pardinas, A.; Stahl, E.; Smoller, J.; Rietschel, M.; Bipolar Working Group of the Psychiatric Genomics, ; Major Depressive Disorder Working Group of the Psy, ; Owen, M.; Walters, J.; O'Donovan, M.; McGrath, J.; Hjerling-Leffler, J.; Sullivan, P.; Goddard, M.; Visscher, P. M.; Yang, J.; Wray, N. R.

10.1101/592899 — genetics — Posted on 2019-03-30

186 Meta-MultiSKAT: Multiple phenotype meta-analysis for region-based association test

Dutta, D.; Gagliano Taliun, S. A.; Weinstock, J. S.; Zawistowski, M.; Sidore, C.; Fritsche, L. G.; Cucca, F.; Schlessinger, D.; Abecasis, G. R.; Brummett, C. M.; Lee, S.

10.1101/593814 — genetics — Posted on 2019-03-30

187 Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers

Schuhmacher, L.-N.; Callejo, G.; Srivats, S.; Smith, E. S. J.

10.1101/166272 — neuroscience — Posted on 2019-03-30

188 Multidimensional estimation of cardiac arrhythmia potential across space and time

Sahli Costabal, F.; Seo, K.; Ashley, E.; Kuhl, E.

10.1101/545863 — biophysics — Posted on 2019-03-29

189 Functional relevance of dual olfactory bulb in olfactory coding

Kuruppath, P.; Belluscio, L.

10.1101/588996 — neuroscience — Posted on 2019-03-29

190 Development of senescence biomarkers in the common woodlouse

Depeux, C.; Samba-Louaka, A.; Becking, T.; Braquart-Varnier, C.; Moreau, J.; Lemaitre, J.-F.; Laverre, T.; Paulhac, H.; Dechaume-Montcharmont, F.-X.; Gaillard, J.-M.; Beltran-Bech, S.

10.1101/583914 — evolutionary biology — Posted on 2019-03-29

191 UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy

10.1101/592980 — physiology — Posted on 2019-03-29

192 Yellow Fever Vaccine Protects Resistant and Susceptible Mice Against Zika Virus Infection

Vicente Santos, A. C.; Guedes-da-Silva, F. H.; Dumard, C. H.; Ferreira, V. N. S.; da Costa, I. P. S.; Machado, R. A.; Barros-Aragao, F. G. Q.; Neris, R. L. S.; Dos-Santos, J. S.; Assuncao-Miranda, I.; Figueiredo, C. P.; Dias, A. A.; Gomes, A. M. O.; de Matos Guedes, H. L.; Oliveira, A. C.; Silva, J. L.

10.1101/587444 — immunology — Posted on 2019-03-29

193 Proteins encoded by Novel ORFs have increased disorder but can be biochemically regulated and harbour pathogenic mutations

Jagannathan, N. S.; Meena, N.; Bhayankaram, K. P.; Prabakaran, S.

10.1101/562835 — genetics — Posted on 2019-03-29

194 Machine learning applied to predicting microorganism growth temperatures and enzyme catalytic optima

Li, G.; Rabe, K. S.; Nielsen, J.; Engqvist, M. K.

10.1101/522342 — bioinformatics — Posted on 2019-03-29

195 Genome-scale model of Rhodotorula toruloides metabolism

Tiukova, I. A.; Prigent, S.; Sandgren, M.; Nielsen, J.; Kerkhoven, E. J.

10.1101/528489 — systems biology — Posted on 2019-03-29

196 PRISMOID: a comprehensive 3D structure database for post-translational modifications and mutations with functional impact

Li, F.; Fan, C.; Marquez-Lago, T. T.; Leier, A.; Revote, J.; Jia, C.; Zhu, Y.; Smith, A. I.; Webb, G. I.; Liu, Q.; Wei, L.; Li, J.; Song, J.

10.1101/523308 — bioinformatics — Posted on 2019-03-29

197 Impact of temperature and photoperiod on survival and biomarkers of senescence in common woodlouse

DEPEUX, C.; SAMBA-LOUAKA, A.; BRAQUART-VARNIER, C.; MOREAU, J.; LEMAITRE, J.-F.; LAVERRE, T.; PAULHAC, H.; DECHAUME-MONCHARMONT, F.-X.; GAILLARD, J.-M.; BELTRAN-BECH, S.

10.1101/433011 — evolutionary biology — Posted on 2019-03-29

198 A simple genetic architecture and low constraint allows rapid floral evolution in a diverse and recently radiating plant genus

Kostyun, J. L.; Gibson, M. J. S.; King, C. M.; Moyle, L. C.

10.1101/516377 — evolutionary biology — Posted on 2019-03-29

199 A keeper of many crypts: the parasitoid Euderus set manipulates the behavior of a taxonomically diverse array of oak gall wasp species

Ward, A. K. G.; Khodor, O. S.; Egan, S. P.; Weinersmith, K. L.; Forbes, A. A.

10.1101/516104 — ecology — Posted on 2019-03-29

200 Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

Howe, L. J.; Lawson, D. J.; Davies, N. M.; St. Pourcain, B.; Lewis, S. J.; Davey Smith, G.; Hemani, G.

10.1101/418269 — genetics — Posted on 2019-03-29

201 Molecular evolution across developmental time reveals rapid divergence in early embryogenesis

Cutter, A. D.; Garrett, R. H.; Mark, S.; Wang, W.; Sun, L.

10.1101/518621 — evolutionary biology — Posted on 2019-03-29

202 An agent-based framework for improving wildlife disease surveillance: A case study of chronic wasting disease in Missouri white-tailed deer.

Belsare, A.; Gompper, M. E.; Keller, B.; Sumners, J.; Hansen, L.; Millspaugh, J.

10.1101/478610 — ecology — Posted on 2019-03-29

203 The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis

Nunes, Q. M.; Su, D.; Brownridge, P. J.; Simpson, D. M.; Sun, C.; li, y.; Bui, P. T. P.; Zhang, X.; Huang, W.; Rigden, D. J.; Beynon, R. J.; Sutton, R.; Fernig, D. G.

10.1101/497271 — biochemistry — Posted on 2019-03-29

204 Proof of concept continuous event logging in living cells

Shur, A.; Murray, R. M.

10.1101/225151 — synthetic biology — Posted on 2019-03-29

205 Electrophysiological correlates of hyperoxia during resting-state EEG in awake human subjects

Vuong, W.; Kizuk, S. A. D.; MacLean, J.; Dickson, C. T.; Mathewson, K.

10.1101/355941 — neuroscience — Posted on 2019-03-29

206 Cardiac afferent activity modulates early neural signature of error detection during skilled performance

Bury, G.; Garcia Huescar, M.; Bhattacharya, J.; Herrojo Ruiz, M.

10.1101/484584 — neuroscience — Posted on 2019-03-29

207 Estimating DNA-DNA interaction frequency from Hi-C data at restriction-fragment resolution

Cameron, C. J.; Dostie, J.; Blanchette, M.

10.1101/377523 — bioinformatics — Posted on 2019-03-29

208 Genome sequence of the euryhaline Javafish medaka, Oryzias javanicus: a small aquarium fish model for studies on adaptation to salinity.

Takehana, Y.; Zahm, M.; Cabau, C.; Klopp, C.; Roques, C.; Bouchez, O.; Donnadieu, C.; Barrachina, C.; Journot, L.; Kawaguchi, M.; Yasumasu, S.; Ansai, S.; Naruse, K.; Inoue, K.; Shinzato, C.; Schartl, M.; Guiguen, Y.; Herpin, A.

10.1101/593673 — genomics — Posted on 2019-03-29

209 Single cell transcriptomics identifies master regulators of dysfunctional pathways in SOD1 ALS motor neurons

Namboori, S. C.; Thomas, P.; Ames, R.; Garrett, L. O.; Willis, C. R. G.; Stanton, L. W.; Bhinge, A.

10.1101/593129 — genomics — Posted on 2019-03-29

210 Degenerate time-dependent network dynamics anticipate seizures in human epileptic brain

Tauste Campo, A.; Principe, A.; Ley, M.; Rocamora, R.; Deco, G.

10.1101/080739 — neuroscience — Posted on 2019-03-29

211 The representational space of observed actions

Tucciarelli, R.; Wurm, M.; Baccolo, E.; Lingnau, A.

10.1101/592071 — neuroscience — Posted on 2019-03-29

212 Driving the scalability of DNA-based information storage systems

Tomek, K. J.; Volkel, K.; Simpson, A.; Hass, A. G.; Indermaur, E. W.; Tuck, J.; Keung, A. J.

10.1101/591594 — bioengineering — Posted on 2019-03-29

213 Seasonal stability and dynamics of DNA methylation in plants in a natural environment

Ito, T.; Nishio, H.; Tarutani, Y.; Emura, N.; Honjo, M. N.; Toyoda, A.; Fujiyama, A.; Kakutani, T.; Kudoh, H.

10.1101/589465 — plant biology — Posted on 2019-03-29

214 Versatile proteome labelling in fruit flies with SILAF

Schober, F. A.; Atanassov, I.; Moore, D.; Wedell, A.; Freyer, C.; Wredenberg, A.

10.1101/590315 — molecular biology — Posted on 2019-03-29

215 CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation.

Demetriou, P.; Abu-Shah, E.; McCuaig, S.; Mayya, V.; Valvo, S.; Korobchevskaya, K.; Friedrich, M.; Mann, E.; Lee, L. Y.; Starkey, T.; Kutuzov, M. A.; Afrose, J.; Siokis, A.; Oxford IBD Cohort Investigators, ; Meyer-Hermann, M.; Depoil, D.; Dustin, M. L.

10.1101/589440 — immunology — Posted on 2019-03-29

216 Compounding the disturbance: Family forest owner reactions to invasive forest insects

Markowski-Lindsay, M.; Borsuk, M. E.; Butler, B. J.; Duveneck, M. J.; Holt, J.; Kittredge, D. B.; Laflower, D.; MacLean, M. G.; Orwig, D.; Thompson, J. R.

10.1101/590331 — ecology — Posted on 2019-03-29

217 Microglia actively remodels adult hippocampal neurogenesis through the phagocytosis secretome

Diaz-Aparicio, I.; Paris, I.; Sierra-Torre, V.; Plaza-Zabala, A.; Rodriguez-Iglesias, N.; Marquez-Ropero, M.; Beccari, S.; Abiega, O.; Alberdi, E.; Matute, C.; Bernales, I.; Schulz, A.; Otrokocsi, L.; Sperlagh, B.; Happonen, K. E.; Lemke, G.; Maletic-Savatic, M.; Valero, J.; Sierra, A.

10.1101/583849 — cell biology — Posted on 2019-03-29

218 Valid and powerful statistical test for decoding accuracy-proposal of Permutation-based Information Prevalence Inference using the i-th order statistic

Hirose, S.

10.1101/578930 — neuroscience — Posted on 2019-03-29

219 Variational Treatment of Trial-by-Trial Drift-Diffusion Models of Behaviour

Vincent, M.; Alexandre, Z.

10.1101/220517 — neuroscience — Posted on 2019-03-29

220 UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy

10.1101/592980 — physiology — Posted on 2019-03-29

221 Induction of p73, Δ133p53, Δ160p53, pAKT leads to neuroprotection via DNA repair by 5-LOX inhibition

Shekhar, S.; Dey, S.

10.1101/593202 — neuroscience — Posted on 2019-03-29

222 C. elegans discriminate colors without eyes or opsins

Ghosh, D. D.; Jin, X.; Nitabach, M.

10.1101/092072 — neuroscience — Posted on 2019-03-29

223 Altered hypothalamic microstructure in human obesity

Thomas, K.; Beyer, F.; Lewe, G.; Zhang, R.; Schindler, S.; Schoenknecht, P.; Stumvoll, M.; Villringer, A.; Witte, A. V.

10.1101/593004 — neuroscience — Posted on 2019-03-29

224 Inhibition of the DDX3 prevents HIV-1 Tat and cocaine-induced neurotoxicity by targeting microglia activation

Aksenova, M.; Sybrand, J.; Cui, B.; Sikirzhytski, V.; Ji, H.; Odhiambo, D.; Lucius, M.; Turner, J. R.; Broude, E.; Pena, E.; Lizzaraga, S.; Zhu, J.; Safro, I.; Wyatt, M. D.; Shtutman, M.

10.1101/591438 — neuroscience — Posted on 2019-03-29

225 A ‘proton ratchet’ for coupling the membrane potential to protein transport

Allen, W. J.; Corey, R. A.; Watkins, D. W.; Pereira, G. C.; Oliveira, A. S. F.; Collinson, I.

10.1101/592543 — biochemistry — Posted on 2019-03-29

226 A sensitive period in the neural phenotype of language in blind individuals

Pant, R.; Kanjlia, S.; Bedny, M.

10.1101/592345 — neuroscience — Posted on 2019-03-29

227 Class I and II aminoacyl-tRNA synthetase tRNA groove discrimination created the first synthetase·tRNA cognate pairs and was therefore essential to the origin of genetic coding

Carter, C. W.; Wills, P. R.

10.1101/593269 — genetics — Posted on 2019-03-29

228 How often do Protein Genes Navigate Valleys of Low Fitness?

Nelson, E. D.; Grishin, N. V.

10.1101/592444 — genetics — Posted on 2019-03-29

229 Structure-function analysis of ZAR1 immune receptor reveals key molecular interactions for activity

Baudin, M.; Schreiber, K. J.; Martin, E. C.; Petrescu, A. J.; Lewis, J.

10.1101/592824 — plant biology — Posted on 2019-03-29

230 Precuneus stimulation alters the neural dynamics of autobiographical memory retrieval

Hebscher, M.; Ibrahim, C.; Gilboa, A.

10.1101/592436 — neuroscience — Posted on 2019-03-29

231 MicroRNA levels in bone and blood change during bisphosphonate and teriparatide therapy in an animal model of postmenopausal osteoporosis

Kocijan, R.; Weigl, M.; Skalicky, S.; Geiger, E.; Ferguson, J.; Leinfellner, G.; Heimel, P.; Pietschmann, P.; Grillari, J.; Redl, H.; Hackl, M.

10.1101/591990 — molecular biology — Posted on 2019-03-29

232 Extended insight into the preponderance of LRRs - a docking & simulation study with members of the TLR1 subfamily

Dey, D.; Dhar, D.; Das, S.; Maulik, A.; Basu, S.

10.1101/592626 — bioinformatics — Posted on 2019-03-29

233 Genomics In The Jungle: Using Portable Sequencing As A Teaching Tool In Field Courses

Watsa, M.; Erkenswick, G. A.; Pomerantz, A.; Prost, S.

10.1101/581728 — scientific communication and education — Posted on 2019-03-29

234 Is there more room to improve? The lifespan trajectory of procedural learning and its relationship to the between- and within-group differences in average response times

Juhasz, D.; Nemeth, D.; Janacsek, K.

10.1101/593582 — neuroscience — Posted on 2019-03-29

235 Multi-omics co-localization with genome-wide association studies reveals context-specific mechanisms of asthma risk variants

Soliai, M.; Kato, A.; Stanhope, C. T.; Norton, J. E.; Naughton, K. A.; Klinger, A. I.; Kern, R. C.; Tan, B. K.; Schleimer, R. P.; Nicolae, D. L.; Pinto, J. M.; Ober, C.

10.1101/593558 — genetics — Posted on 2019-03-29

236 Divergent mitochondrial and nuclear OXPHOS genes are candidates for genetic incompatibilities in Ficedula Flycatchers

van der Heijden, E.; McFarlane, E.; van der Valk, T.; Qvarnstrom, A.

10.1101/588756 — evolutionary biology — Posted on 2019-03-29

237 Patterning of the vertebrate head in time and space by BMP signalling

Zhu, K.; Spaink, H. P.; Durston, A.

10.1101/592451 — developmental biology — Posted on 2019-03-29

238 Characterisation of Staphylococcus aureus lipids by nanoelectrospray ionisation tandem mass spectrometry (nESI-MS/MS)

Young, S. A.; Desbois, A. P.; Coote, P. J.; Smith, T. K.

10.1101/593483 — microbiology — Posted on 2019-03-29

239 Treatment of mice with IL2-complex enhances inflammasome-driven IFN-γ production and prevents lethal toxoplasmosis

Kupz, A.; Pai, S.; Giacomin, P. R.; Whan, J. A.; Walker, R.; Hammoudi, P.-M.; Smith, N.; Miller, C. M.

10.1101/593574 — microbiology — Posted on 2019-03-29

240 Health service utilisation lags behind maternal diseases or illnesses during pregnancy in rural south Ethiopia: A prospective cohort study

Borde, M. T.; Loha, E.; Johansson, K. A.; Lindtjorn, B.

10.1101/593525 — epidemiology — Posted on 2019-03-29

241 Dynamics of soil nematode communities revealed significant variation in greenhouse with different continuous cropping years

Tian, X.; Zhao, X.; Mao, Z.; Xie, B.

10.1101/593541 — ecology — Posted on 2019-03-29

242 Vibrational behavior of psyllids (Hemiptera: Psylloidea): functional morphology and mechanisms

Liao, Y.-C.; Wu, Z.-Z.; Yang, M.-M.

10.1101/593533 — animal behavior and cognition — Posted on 2019-03-29

243 Highly reproducible murine model of oral Salmonella infection via inoculated food

Nilsson, O. R.; Kari, L.; Steele-Mortimer, O.

10.1101/593442 — microbiology — Posted on 2019-03-29

244 Circulating Th17.1 cells as candidate for prediction of therapeutic response to abatacept in patients with rheumatoid arthritis: exploratory research

Maeda, S.; Osaga, S.; Maeda, T.; Takeda, N.; Tamechika, S.-y.; Naniwa, T.; Niimi, A.

10.1101/593475 — immunology — Posted on 2019-03-29

245 Feeding behavior of Aedes (Aedimorphus) vexans arabiensis, a Rift valley fever virus vector in the Ferlo pastoral ecosystem of Senegal.

BITEYE, B.; Fall, A. G.; Seck, M. T.; Ciss, M.; Diop, M.; Gimonneau, G.

10.1101/593491 — epidemiology — Posted on 2019-03-29

246 Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic β-cells

Pratt, E. P. S.; Harvey, K. E.; Salyer, A. E.; Tang, s.; Hockerman, G.

10.1101/593418 — pharmacology and toxicology — Posted on 2019-03-29

247 Gene Cascade Finder: A tool for identification of gene cascades and its application in Caenorhabditis elegans

Ito, M.; Nomoto, Y.; Kubota, Y.; Kasahara, K.; Tomita, A.; Oshime, T.; Yamashita, H.; Fahmi, M.

10.1101/593400 — genomics — Posted on 2019-03-29

248 Multivariate Genome-wide Association Analyses Reveal the Genetic Basis of Seed Fatty Acid Composition in Oat (Avena sativa L.)

Carlson, M. O.; Montilla-Bascon, G.; Hoekenga, O. A.; Tinker, N. A.; Poland, J.; Baseggio, M.; Sorrells, M.; Jannink, J.-L.; Gore, M. A.; Yeats, T. H.

10.1101/589952 — genetics — Posted on 2019-03-29

249 Assessing the multiple dimensions of poverty. Data mining approaches to the 2004-14 Health and Demographic Surveillance System in Cuatro Santos, Nicaragua

Kallestal, C.; Zelaya Blandon, E.; Pena, R.; Perez, W.; Contreras, M.; Persson, L.-A.; Sysoev, O.; Ekholm Selling, K.

10.1101/593426 — epidemiology — Posted on 2019-03-29

250 Lipidome profiles of postnatal day 2 vaginal swabs reflect fat composition of gilts postnatal diet

Harlow, K.; Ferreira, C. R.; Sobreira, T. J. P.; Casey, T. M.; Stewart, K.

10.1101/593392 — developmental biology — Posted on 2019-03-29

251 A combined strategy of neuropeptide predictions and tandem mass spectrometry identifies evolutionarily conserved ancient neuropeptides in the sea anemone Nematostella vectensis

Hayakawa, E.; Watanabe, H.; Menschaert, G.; Holstein, T.; Baggerman, G.; Schoofs, L.

10.1101/593384 — biochemistry — Posted on 2019-03-29

252 Quantitative Colour Pattern Analysis (QCPA): A Comprehensive Framework for the Analysis of Colour Patterns in Nature

van den Berg, C. P.; Troscianko, J.; Endler, J. A.; Marshall, N. J.; Cheney, K. L.

10.1101/592261 — animal behavior and cognition — Posted on 2019-03-29

253 Effects of single cage housing in the rat and mouse pilocarpine models of epilepsy

Manouze, H.; Ghestem, A.; Poillerat, V.; Bennis, M.; Ba-M'hamed, S.; Benoliel, J.-J.; Becker, C.; Bernard, C.

10.1101/214528 — neuroscience — Posted on 2019-03-29

254 Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell Lymphocyte Attenuator

Bitra, A.; Nemcovicova, I.; Picarda, G.; Doukov, T.; Wang, J.; Benedict, C. A.; Zajonc, D. M.

10.1101/591883 — immunology — Posted on 2019-03-29

255 Control of human testis-specific gene expression

Brown, J.

10.1101/593376 — developmental biology — Posted on 2019-03-29

256 Polygenic architecture of human neuroanatomical diversity

Biton, A.; Traut, N.; Poline, J.-B.; Aribisala, B. S.; Bastin, M. E.; Bülow, R.; Cox, S. R.; Deary, I. J.; Grabe, H. J.; Hagenaars, S.; Hashimoto, R.; Munoz Maniega, S.; Nauck, M.; Royle, N. A.; Teumer, A.; Valdes Hernandez, M.; Völker, U.; Wardlaw, J. M.; Wittfeld, K.; Alzheimer's Disease Neuroimaging Initiative, ; Bourgeron, T.; Toro, R.

10.1101/592337 — neuroscience — Posted on 2019-03-29

257 IκBζ is constitutively expressed in human and murine airway epithelium

Sundaram, K.; Mitra, S.; Jaynes, F.; Lorscheid, S.; Steiner, H.; Flechtner, A.; Sarkar, A.; Shilo, K.; Boyaka, P. N.; Schulze-Osthoff, K.; Wewers, M. D.

10.1101/255331 — immunology — Posted on 2019-03-29

258 Noisy Perturbation Models Distinguish Network Specific from Embedding Variability

Piehler, A.

10.1101/550467 — systems biology — Posted on 2019-03-29

259 A simplified analytical model of sound propagationin the human ear

Gambin, W. L.

10.1101/571034 — bioengineering — Posted on 2019-03-29

260 Investigating the longitudinal consistency and genetic architecture of non-cognitive skills, and their relation to educational attainment

Morris, T. T.; Davey Smith, G.; Van den Berg, G.; Davies, N. M.

10.1101/470682 — genetics — Posted on 2019-03-29

261 Non-catalytic binding sites induce weaker long-range evolutionary rate gradients than catalytic sites in enzymes

Sharir-Ivry, A.; Xia, Y.

10.1101/554436 — evolutionary biology — Posted on 2019-03-29

262 Block HSIC Lasso: model-free biomarker detection for ultra-high dimensional data

Climente-Gonzalez, H.; Azencott, C.-A.; Kaski, S.; Yamada, M.

10.1101/532192 — bioinformatics — Posted on 2019-03-29

263 diffcyt: Differential discovery in high-dimensional cytometry via high-resolution clustering

Weber, L. M.; Nowicka, M.; Soneson, C.; Robinson, M. D.

10.1101/349738 — bioinformatics — Posted on 2019-03-29

264 Axonal tree morphology and signal propagation dynamics improve interneuron classification

Ofer, N.; Shefi, O.; Yaari, G.

10.1101/414615 — neuroscience — Posted on 2019-03-29

265 The effect of stimulus choice on an EEG-based objective measure of speech intelligibility

Verschueren, E.; Vanthornhout, J.; Francart, T.

10.1101/421727 — neuroscience — Posted on 2019-03-29

266 EFFECT OF PARENTAL CARE ON REPRODUCTIVE SUCCESS IN WOOD STORKS (MYCTERIA AMERICANA)

Bruant, A.; Picardi, S.; Frederick, P.; Basille, M.

10.1101/592840 — zoology — Posted on 2019-03-28

267 Hierarchy of connectivity-function relationship of the human cortex revealed through predicting activity across functional domains

Wu, D.; Fan, L.; Song, M.; Wang, H.; Chu, C.; Yu, S.; Jiang, T.

10.1101/591776 — neuroscience — Posted on 2019-03-28

268 VRmol: an Integrative Cloud-Based Virtual Reality System to Explore Macromolecular Structure

Xu, K.; Liu, N.; Xu, J.; Guo, C.; Zhao, L.; Wang, H.-w.; Zhang, Q. C.

10.1101/589366 — bioinformatics — Posted on 2019-03-28

269 A stochastic spatial model for heterogeneity in cancergrowth

Queiroga, A. S.; de Morais, M. C. C.; Tortelli, T. C.; Chammas, R.; Ramos, A. F.

10.1101/584573 — systems biology — Posted on 2019-03-28

270 Revealing virulence potential of clinical and environmental Aspergillus fumigatus isolates using Whole-genome sequencing

Puertolas-Balint, F.; Rossen, J. W.; Oliveira dos Santos, C.; Chlebowicz, M. A.; Raangs, E.; van Putten, M. L.; Sola-Campoy, P. J.; Han, L.; Schmidt, M.; Garcia-Cobos, S.

10.1101/587402 — microbiology — Posted on 2019-03-28

271 Integration of pathway, cellular and genetic context reveals principles of synthetic lethality that affect reproducibility

Ku, A. A.; Kongara, S.; Hu, H.-M.; Zhao, X.; Wu, D.; McCormick, F.; Balmain, A.; Bandyopadhyay, S.

10.1101/591677 — cancer biology — Posted on 2019-03-28

272 A triple-hybrid cross reveals a new hybrid incompatibility locus between D. melanogaster and D. sechellia

Cooper, J. C.; Guo, P.; Bladen, J.; Phadnis, N.

10.1101/590588 — evolutionary biology — Posted on 2019-03-28

273 Resilience Analysis for Competing Populations

Cesar Fassoni, A.; de Carvalho Braga, D.

10.1101/578609 — ecology — Posted on 2019-03-28

274 Proteomic characterization of the Mycobacterium marinum-containing vacuole in Dictyostelium discoideum

Gueho, A.; Bosmani, C.; Soldati, T.

10.1101/592717 — systems biology — Posted on 2019-03-28

275 Aligning Needs: Integrating Citizen Science Efforts into Schools Through Service Requirements.

Tsueng, G.; Kumar, A.; Nanis, M.; Su, A. I.

10.1101/304766 — scientific communication and education — Posted on 2019-03-28

276 First evidence that intrinsic fetal heart rate variability exists and is affected by hypoxic pregnancy

Frasch, M. G.; Herry, C.; Niu, Y.; Giussani, D. A.

10.1101/242107 — physiology — Posted on 2019-03-28

277 A gene based approach to test genetic association based on an Optimally Weighted Combination of Multiple Traits

Zhang, J.; Qiuying, S.; Guanfu, L.; Wang, X.

10.1101/592568 — genetics — Posted on 2019-03-28

278 Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules

Scott, S.; Shaheen, C.; McGuinness, B.; Metera, K.; Kouzine, F.; Levens, D.; Benham, C. J.; Leslie, S.

10.1101/591008 — biophysics — Posted on 2019-03-28

279 TET2 regulates the neuroinflammatory response in microglia

Carrillo-Jimenez, A.; Deniz, O.; Niklison-Chirou, M.; Ruiz-Laza, R.; Salomao, K.; Stratoulias, V.; Amoroux, R.; Yip, P.; Vilalta, A.; Cheray, M.; Scott-Egerton, A. M.; Rivas, E.; Tayara, K.; Garcia-Dominguez, I.; Garcia-Revilla, J.; Fernandez-Martin, J. C.; Espinosa-Oliva, A. M.; Shen, X.; StGeorge-Hyslop, P.; Brown, G.; Hajkova, P.; Joseph, B.; Venero, J. L.; Branco, M. R.; Burguillos, M. A.

10.1101/592055 — neuroscience — Posted on 2019-03-28

280 A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits

Foley, C. N.; Staley, J. R.; Breen, P. G.; Sun, B. B.; Kirk, P. D.; Burgess, S.; Howson, J. M.

10.1101/592238 — genetics — Posted on 2019-03-28

281 Intergenerational effects of early adversity on survival in wild baboons

Zipple, M. N.; Archie, E. A.; Tung, J.; Altmann, J.; Alberts, S. C.

10.1101/591248 — zoology — Posted on 2019-03-28

282 A segregating human allele of SPO11 modeled in mice disrupts timing and amounts of meiotic recombination, causing oligospermia and a decreased ovarian reserve.

Tran, T. N.; Schimenti, J. C.

10.1101/592576 — genetics — Posted on 2019-03-28

283 Genetic Testing Preferences and Intentions in U.S. Patients with Clinically Diagnosed Familial Hypercholesterolemia

Wand, H.; Sturm, A. C.; Erby, L.; Kindt, I.; Klein, W. M. P.

10.1101/587923 — genetics — Posted on 2019-03-28

284 Research grade marijuana supplied by the National Institute on Drug Abuse is genetically divergent from commercially available Cannabis

Schwabe, A. L.; Hansen, C. J.; Hyslop, R. M.; McGlaughlin, M. E.

10.1101/592725 — genetics — Posted on 2019-03-28

285 A Mechanism for Epithelial-Mesenchymal Heterogeneity in a Population of Cancer Cells

Tripathi, S.; Levine, H.; Jolly, M. K.

10.1101/592691 — cancer biology — Posted on 2019-03-28

286 Bocaparvovirus, Erythroparvovirus and Tetraparvovirus in New World Monkeys from Central America

Chaves, A.; Ibarra-Cerdena, C. N.; Lopez-Perez, A. M.; Monge, O.; Avendano, R.; Urena-Saborio, H.; Chavarria, M.; Zaldana, K.; Sanchez, L.; Ortiz-Malavassi, E.; Suzan, G.; Foley, J.; Gutierrez-Espeleta, G. A.

10.1101/588079 — epidemiology — Posted on 2019-03-28

287 Validation and characterization of a DNA methylation alcohol biomarker across the life course

Yousefi, P. D.; Richmond, R.; Langdon, R.; Ness, A. R.; Liu, C.; Levy, D.; Relton, C.; Suderman, M.; Zuccolo, L.

10.1101/591404 — epidemiology — Posted on 2019-03-28

288 An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data

Stern, A. J.; Wilton, P. R.; Nielsen, R.

10.1101/592675 — genetics — Posted on 2019-03-28

289 Factors underpinning discrepant findings from reviews on the same topic: A systematic analysis of Cochrane and non-Cochrane reviews

Nunan, D.; Hacke, C.

10.1101/574046 — epidemiology — Posted on 2019-03-28

290 Prediction of rapid kidney function decline using machine learning combining blood biomarkers and electronic health record data

Nadkarni, G. N.; Fleming, F.; McCullough, J. R.; Chauhan, K.; Verghese, D. A.; He, J. C.; Quackenbush, J.; Bonventre, J. V.; Murphy, B.; Parikh, C. R.; Donovan, M.; Coca, S. G.

10.1101/587774 — epidemiology — Posted on 2019-03-28

291 Polygenic risk score for Alzheimer’s disease and trajectories of cardiometabolic risk factors in children

Korologou-Linden, R.; O'Keeffe, L.; Howe, L.; Davey Smith, G.; Jones, H.; Anderson, E. L.; Stergiakouli, E.

10.1101/580548 — epidemiology — Posted on 2019-03-28

292 Accurate forecasts of the effectiveness of interventions against Ebola may require models that account for variations in symptoms during infection

Hart, W.; Hochfilzer, L.; Cunniffe, N.; Lee, H.; Nishiura, H.; Thompson, R. N.

10.1101/592030 — epidemiology — Posted on 2019-03-28

293 Global phylogeographical patterns in the spread of foot-and-mouth disease virus

Jara, M.; Frias-De-Diego, A.; Dellicour, S.; Baele, G.; Machado, G.

10.1101/590612 — epidemiology — Posted on 2019-03-28

294 Phenotyping women based on dietary macronutrients, physical activity and body weight using machine-learning tools

Ramyaa, R.; Hosseini, O.; Krishnan, G. P.; Krishnan, S.

10.1101/587220 — epidemiology — Posted on 2019-03-28

295 Increasing global heterogeneity in the life expectancy of older populations

Liou, L.; Subramanian, S.; Joe, W.

10.1101/589630 — epidemiology — Posted on 2019-03-28

296 High burden and seasonal variation of paediatric scabies and pyoderma prevalence in The Gambia: a cross-sectional study

Armitage, E. P.; Senghore, E.; Darboe, S.; Barry, M.; Camara, J.; Bah, S.; Marks, M.; Cerami, C.; Roca, A.; Antonio, M.; Turner, C.; de Silva, T.

10.1101/591537 — epidemiology — Posted on 2019-03-28

297 The effect of combined patching and citalopram on visual acuity in adults with amblyopia: a randomized, crossover, placebo-controlled trial

Lagas, A. K.; Black, J. M.; Russell, B. R.; Kydd, R. R.; Thompson, B.

10.1101/587980 — clinical trials — Posted on 2019-03-28

298 ‘Early Rectangularization’ of under-5 mortality in sub-Saharan Africa: compression, convergence, inequality

Mejia-Guevara, I.; Tuljapurkar, S.

10.1101/591925 — epidemiology — Posted on 2019-03-28

299 The causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank

Dixon, P.; Hollingworth, W.; Harrison, S.; Davies, N.; Davey Smith, G.

10.1101/589820 — epidemiology — Posted on 2019-03-28

300 Global state of deworming coverage and inequity in low-income and middle-income countries: a spatiotemporal study of household health surveys

Lo, N. C.; Heft-Neal, S.; Coulibaly, J. T.; Leonard, L.; Bendavid, E.; Addiss, D. G.

10.1101/589127 — epidemiology — Posted on 2019-03-28

301 Impact of a caries preventive intervention in remote Indigenous Australian children

Lalloo, R.; SANTOSH KUMAR, T.; Kroon, J.; Jamieson, L. M.; Johnson, N.

10.1101/585935 — epidemiology — Posted on 2019-03-28

302 Phylodynamic and Evolutionary analysis of Rotavirus G12 in Africa

Motayo, B. O.; Oluwasemowo, O. O.; Olusola, B. A.; Opayele, A.; Faneye, A. O.

10.1101/591297 — epidemiology — Posted on 2019-03-28

303 Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD).

Cole, E. J.; Stimpson, K. H.; Gulser, M.; Cherian, K.; Tischler, C.; Nejad, R.; Bentzley, B. S.; Pankow, H.; Choi, E.; Aaron, H.; Espil, F. M.; Pannu, J.; Xiao, X.; Duvio, D.; Solvason, H. B.; Hawkins, J.; Keller, J.; Schatzberg, A. F.; Sudheimer, K. D.; Williams, N. R.

10.1101/581280 — clinical trials — Posted on 2019-03-28

304 State-dependent geometry of population activity in rat auditory cortex

Kobak, D.; Pardo-Vazquez, J. L.; Valente, M.; Machens, C.; Renart, A.

10.1101/501338 — neuroscience — Posted on 2019-03-28

305 Voice patterns in schizophrenia: A systematic review and Bayesian meta-analysis

Parola, A.; Simonsen, A.; Bliksted, V.; Fusaroli, R.

10.1101/583815 — bioinformatics — Posted on 2019-03-28

306 Ecological causes of uneven diversification and richness in the mammal tree of life

Upham, N. S.; Esselstyn, J. A.; Jetz, W.

10.1101/504803 — evolutionary biology — Posted on 2019-03-28

307 μSleep: A Spontaneous C. elegans Sleep State Regulated by Satiety, Thermosensation and Mechanosensation

Gonzales, D. L.; Zhou, J.; Robinson, J. T.

10.1101/547075 — neuroscience — Posted on 2019-03-28

308 Loss of cytoplasmic incompatibility and minimal fecundity effects explain relatively low Wolbachia frequencies in Drosophila mauritiana

Meany, M. K.; Conner, W. R.; Richter, S. V.; Bailey, J. A.; Turelli, M.; Cooper, B. S.

10.1101/461574 — evolutionary biology — Posted on 2019-03-28

309 Designing Minimal Genomes Using Whole-Cell Models

Rees, J.; Chalkley, O.; Landon, S.; Purcell, O.; Marucci, L.; Grierson, C.

10.1101/344564 — synthetic biology — Posted on 2019-03-28

310 Bidirectional Long-Term Synaptic Zinc Plasticity at Mouse Glutamatergic Synapses

Vogler, N. W.; Tzounopoulos, T.

10.1101/320671 — neuroscience — Posted on 2019-03-28

311 Real-time projections of epidemic transmission and estimation of vaccination impact during an Ebola virus disease outbreak in Northeastern Democratic Republic of Congo

Worden, L.; Wannier, R.; Hoff, N. A.; Musene, K.; Selo, B.; Mossoko, M.; Okitolonda-Wemakoy, E.; Muyembe-Tamfum, J. J.; Rutherford, G. W.; Lietman, T. M.; Rimoin, A. W.; Porco, T. C.; Kelly, J. D.

10.1101/461285 — epidemiology — Posted on 2019-03-28

312 Polygenic architecture of human neuroanatomical diversity

10.1101/592337 — neuroscience — Posted on 2019-03-28

313 Improving spatial normalization of brain diffusion MRI to measure longitudinal changes of tissue microstructure in human cortex and white matter.

Jacobacci, F.; Jovicich, J.; Lerner, G.; Amaro, E.; Armony, J.; Doyon, J.; Della-Maggiore, V.

10.1101/590521 — neuroscience — Posted on 2019-03-28

314 The mRNA-bound proteome of Leishmania mexicana: novel genetic insight into an ancient parasite

de Pablos, L. M.; Ferreira, T. R.; Dowle, A. A.; Forrester, S.; Parry, E.; Newling, K.; Walrad, P. B.

10.1101/592402 — molecular biology — Posted on 2019-03-28

315 Extensive epitranscriptomic methylation of A and C residues on murine leukemia virus transcripts enhances viral gene expression

Courtney, D.; Chalem, A.; Bogerd, H. P.; Law, B. A.; Kennedy, E. M.; Holley, C. L.; Cullen, B. R.

10.1101/591545 — microbiology — Posted on 2019-03-28

316 EPS8 facilitates uncoating of influenza A virus

Larson, G. P.; Tran, V.; Yu, S.; Cai, Y.; Higgins, C. A.; Smith, D. M.; Baker, S. F.; Radoshitzky, S. R.; Kuhn, J. H.; Mehle, A.

10.1101/592485 — microbiology — Posted on 2019-03-28

317 Construction and analysis of an interologous protein-protein interaction network of Camellia sinensisleaf (TeaLIPIN) from RNA-Seq datasets

Singh, G.; Singh, V.; Singh, V.

10.1101/592394 — systems biology — Posted on 2019-03-28

318 Spatiotemporal dynamics of synthetic microbial consortia in microfluidic devices

Alnahhas, R.; Winkle, J. J.; Hirning, A. J.; Karamched, B.; Ott, W.; Josic, K.; Bennett, M. R.

10.1101/590505 — synthetic biology — Posted on 2019-03-28

319 Ubiquitin receptors are required for substrate-mediated activation of the proteasome’s unfolding ability

Cundiff, M. D.; Hurley, C. M.; Wong, J. D.; Bashyal, A.; Rosenberg, J.; Reichard, E. L.; Nassif, N. D.; Brodbelt, J.; Kraut, D.

10.1101/592378 — biochemistry — Posted on 2019-03-28

320 On a Robust, Sensitive Cell-Free Method for Pseudomonas Sensing and Quantification

Seto, J.; Buske, P.; Laurie, M.

10.1101/256438 — synthetic biology — Posted on 2019-03-28

321 WACS: Improving Peak Calling by Optimally Weighting Controls

Awdeh, A.; Turcotte, M.; Perkins, T. J.

10.1101/582650 — bioinformatics — Posted on 2019-03-28

322 Short term memory properties of sensory neural architectures

Dubreuil, A. M.

10.1101/590851 — neuroscience — Posted on 2019-03-28

323 Childhood socio-economic disadvantage predicts reduced myelin growth across adolescence and young adulthood

Ziegler, G.; Moutoussis, M.; Hauser, T. U.; Fearon, P.; Bullmore, E. T.; Goodyer, I. M.; Fonagy, P.; Jones, P. B.; NeuroScience in Psychiatry Network consortium, ; Lindenberger, U.; Dolan, R. J.

10.1101/589713 — neuroscience — Posted on 2019-03-28

324 A sound-sensitive source of alpha oscillations in human non-primary auditory cortex

Billig, A. J.; Herrmann, B.; Rhone, A. E.; Gander, P. E.; Nourski, K. V.; Snoad, B. F.; Kovach, C. K.; Kawasaki, H.; Howard, M. A.; Johnsrude, I. S.

10.1101/590323 — neuroscience — Posted on 2019-03-28

325 The Complete Chloroplast Genome of Tetraselmis desikacharyi (Chlorodendrophyceae) and Phylogenetic Analysis

Li, L.; Li, H.; Sahu, S. K.; Xu, Y.; Wang, H.; Liang, H.; Wang, S.

10.1101/591727 — genomics — Posted on 2019-03-28

326 Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

Kumar, V.; Doharey, P. K.; Gulati, S.; Meehan, J.; Martinez, M. G.; Hughes, K.; Mooers, B. H. M.; Cruz-Reyes, J.

10.1101/524702 — molecular biology — Posted on 2019-03-28

327 A Polybasic Domain in aPKC Mediates Par-6-Dependent Control of Plasma Membrane Targeting and Kinase Activity

Dong, W.; Lu, J.; Zhang, X.; Wu, Y.; Lettieri, K.; Hammond, G.; Hong, Y.

10.1101/588624 — cell biology — Posted on 2019-03-28

328 Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids

Smits, L. M.; Magni, S.; Grzyb, K.; Antony, P. M.; Krueger, R.; Skupin, A.; Bolognin, S.; Schwamborn, J.

10.1101/589598 — neuroscience — Posted on 2019-03-28

329 Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits

Gleason, K. J.; Yang, F.; Pierce, B.; He, X.; Chen, L. S.

10.1101/579581 — genomics — Posted on 2019-03-28

330 WACS: Improving Peak Calling by Optimally Weighting Controls

Awdeh, A.; Turcotte, M.; Perkins, T. J.

10.1101/582650 — bioinformatics — Posted on 2019-03-28

331 Quantitative Colour Pattern Analysis (QCPA): A Comprehensive Framework for the Analysis of Colour Patterns in Nature

van den Berg, C. P.; Troscianko, J.; Endler, J. A.; Marshall, N. J.; Cheney, K. L.

10.1101/592261 — animal behavior and cognition — Posted on 2019-03-28

332 Rule-governed Dynamic Stochastic Equilibration of Multicellular Motion In Vivo During Olfactory Neurogenesis

Warrier, V.; Cluzeau, C.; Chen, B.-C.; Green-Saxena, A.; Bergey, D. E.; Betzig, E.; Saxena, A.

10.1101/591479 — systems biology — Posted on 2019-03-28

333 Space-independent community and hub structure of functional brain networks

Zamani Esfahlani, F.; Bertolero, M.; Bassett, D.; Betzel, R.

10.1101/590935 — neuroscience — Posted on 2019-03-28

334 Within-subject consistency of paired associative stimulation as assessed by linear mixed models.

Ottenhoff, M. J.; Fani, L.; Erler, N. S.; Castricum, J.; Obdam, I. F.; van der Vaart, T.; Kushner, S. A.; de Wit, M.-C. Y.; Elgersma, Y.; Tulen, J.

10.1101/434431 — neuroscience — Posted on 2019-03-28

335 During hippocampal inactivation, grid cells maintain their synchrony, even when the grid pattern is lost

Almog, N.; Tocker, G.; Bonnevie, T.; Moser, M.-B.; Moser, E. I.; Derdikman, D.

10.1101/592006 — neuroscience — Posted on 2019-03-28

336 Surveillance-embedded genomic outbreak resolution of methicillin-susceptible Staphylococcus aureus in a neonatal intensive care unit

Cremers, A. J. H.; Coolen, J.; Bleeker-Rovers, C.; van der Geest-Blankert, N.; Haverkate, D.; Hendriks, H.; Henriet, S.; Huynen, M.; Kolwijck, E.; Liem, D.; Melchers, W.; Rossen, J.; Zoll, J.; van Heijst, A.; Hopman, J.; Wertheim, H.

10.1101/584359 — microbiology — Posted on 2019-03-28

337 Integrating detection of copy neutral chromosomal losses in a clinical setting in leukemia and lymphoma by means of allelic imbalance and read depth ratio comparison

Hansen, M. C.; Cedile, O.; Ludvigsen, M.; Kjeldsen, E.; Moeller, P. L.; Abildgaard, N.; Hokland, P.; Nyvold, C. G.

10.1101/590752 — bioinformatics — Posted on 2019-03-28

338 High-throughput Phenotyping with Temporal Sequences

Estiri, H.; McCoy, T. H.; Wagholikar, K. B.; Goodson, A. P.; Murphy, K.; Murphy, S. N.

10.1101/590307 — bioinformatics — Posted on 2019-03-28

339 Area-specific mapping of binocular disparity across mouse visual cortex

La Chioma, A.; Bonhoeffer, T.; Hübener, M.

10.1101/591412 — neuroscience — Posted on 2019-03-28

340 A Robust Model for Circadian Redox Oscillations

del Olmo, M.; Kramer, A.; Herzel, H.

10.1101/590570 — molecular biology — Posted on 2019-03-28

341 Feedback loops in the Plk4-STIL-HsSAS6 network coordinate site selection for procentriole formation

Takao, D.; Watanabe, K.; Kuroki, K.; Kitagawa, D.

10.1101/591834 — cell biology — Posted on 2019-03-28

342 Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect

Johnson, K. E.; Howard, G.; Mo, W.; Strasser, M. K.; Lima, E. A. B. F.; Huang, S.; Brock, A.

10.1101/585216 — cancer biology — Posted on 2019-03-28

343 Multiomics data analysis using tensor decomposition based unsupervised feature extraction --Comparison with DIABLO--

Taguchi, Y.-h.

10.1101/591867 — bioinformatics — Posted on 2019-03-28

344 A topological data analysis based classification method for multiple measurement

Riihimaki, H.; Chacholski, W.; Theorell, J.; Hillert, J.; Ramanujam, R.

10.1101/569210 — bioinformatics — Posted on 2019-03-28

345 Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information

Guelfi, S.; D'Sa, K.; Botia, J. A.; Vandrovcova, J.; Reynolds, R. H.; Zhang, D.; Trabzuni, D.; Collado-Torres, L.; Thomason, A.; Quijada Leyton, P.; Gagliano, S. A.; Nalls, M. A.; UK Brain Expression Consortium, ; Small, K. S.; Smith, C.; Ramasamy, A.; Hardy, J. A.; Weale, M. E.; Ryten, M.

10.1101/591156 — bioinformatics — Posted on 2019-03-28

346 Contribution of self- and other-regarding motives to (dis)honesty

Shuster, A.; Levy, D. J.

10.1101/590208 — neuroscience — Posted on 2019-03-28

347 Chitosan films for microfluidic studies of single bacteria and perspectives for antibiotics susceptibility testing

Mignot, T.; Treguier, J.; Bugnicourt, L.; Gay, G.; Diallo, M.; Islam, S. T.; Toro, A.; Theodoly, O.; David, L.; SUDRE, G.

10.1101/591602 — microbiology — Posted on 2019-03-28

348 Bacteriophage adherence to mucus mediates preventive protection against pathogenic bacteria

Almeida, G. M.; Laanto, E.; Ashrafi, R.; Sundberg, L.-R.

10.1101/592097 — microbiology — Posted on 2019-03-28

349 Identification of novel neuroprotective loci modulating ischemic stroke volume in a cross between wild-derived inbred mouse strains

Lee, H. K.; Widmayer, S. J.; Aylor, D. L.; Marchuk, D.

10.1101/591669 — genetics — Posted on 2019-03-28

350 Contingent Convergence: The ability to detect convergent genomic evolution is dependent on demographic similarity

Whiting, J. R.; Fraser, B. A.

10.1101/592105 — evolutionary biology — Posted on 2019-03-28

351 Identifying Lipid Membrane Packing Defects in 3-Dimension: When Depth Does Matter

Tripathy, M.; Srivastava, A.

10.1101/591784 — biophysics — Posted on 2019-03-28

352 Distance Measures for Tumor Evolutionary Trees

DiNardo, Z.; Tomlinson, K.; Ritz, A.; Oesper, L.

10.1101/591107 — bioinformatics — Posted on 2019-03-28

353 Fingerprinting CANDO: Increased Accuracy with Structure and Ligand Based Shotgun Drug Repurposing

Schuler, J.; Samudrala, R.

10.1101/591123 — bioinformatics — Posted on 2019-03-28

354 Human influences on antipredator behaviour in Darwin’s finches

Gotanda, K. M.

10.1101/591651 — animal behavior and cognition — Posted on 2019-03-28

355 Changepoint detection versus reinforcement learning: Separable neural substrates approximate different forms of Bayesian inference

Pauli, W. M.; Jones, M.

10.1101/591818 — neuroscience — Posted on 2019-03-28

356 Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation

KEELE, G. R.; Quach, B. C.; Israel, J. W.; Zhou, Y.; Chappell, G. A.; Lewis, L.; Safi, A.; Simon, J. M.; Cotney, P.; Crawford, G. E.; Wright, F. A.; Valdar, W.; Rusyn, I.; Furey, T. S.

10.1101/588723 — genomics — Posted on 2019-03-28

357 Transgenerational plasticity of inducible defenses: combined effects of grand-parental, parental and current environments

Tariel, J.; Plénet, S.; Luquet, E.

10.1101/589945 — evolutionary biology — Posted on 2019-03-28

358 Statistical Analysis of Variability in TnSeq Data Across Conditions Using Zero-Inflated Negative Binomial Regression

Subramaniyam, S.; DeJesus, M. A.; Saveri, A.; Smith, C. M.; Baker, R. E.; Ehrt, S.; Schnappinger, D.; Sassetti, C. M.; Ioerger, T. R.

10.1101/590281 — bioinformatics — Posted on 2019-03-28

359 Anopheles bionomics, insecticide resistance mechanisms and malaria transmission in the Korhogo area, northern Cote d Ivoire: a pre-intervention study

Zogo, B.; Soma, D. D.; Tchiekoi, B. N. C.; Some, A.; Ahoua Alou, L. P.; Koffi, A. A.; Fournet, F.; Dahounto, A.; Coulibaly, B.; Kande, S.; Dabire, R. K.; Baba-Moussa, L.; Moiroux, N.; Pennetier, C.

10.1101/589556 — zoology — Posted on 2019-03-28

360 Optimizing root measurements in rhizotrons

Ytting, N. K.; kirkegaard, j.; Thorup-Kristensen, K.

10.1101/587329 — plant biology — Posted on 2019-03-28

361 Information Integration and Collective Motility in Phototactic Cyanobacteria

Menon, S. N.; Varuni, P.; Menon, G. I.

10.1101/590778 — microbiology — Posted on 2019-03-28

362 Distinct biogeographic origins of androgenetic Corbicula lineages followed by genetic captures

Etoundi, E.; Marescaux, J.; Vastrade, M.; Debortoli, N.; Hedtke, S. M.; Pigneur, L.-M.; Virgo, J.; Flot, J.-F.; Van Doninck, K.

10.1101/590836 — evolutionary biology — Posted on 2019-03-28

363 Animal evolution coincides with a novel degree of freedom in exocytic transport processes

Kollmar, M.; Welz, T.; Straub, F.; Alzahofi, N.; Hatje, K.; Briggs, D. A.; Samol-Wolf, A.; Burkhardt, P.; Hume, A.; Kerkhoff, E.

10.1101/591974 — cell biology — Posted on 2019-03-28

364 Modeling latent flows on single-cell data using the Hodge decomposition

Maehara, K.; Ohkawa, Y.

10.1101/592089 — bioinformatics — Posted on 2019-03-28

365 Substrate structure and computation guided engineering of a Lipase for Omega-3 fatty acid selectivity

Moharana, T. R.; Rao, N.

10.1101/592063 — biochemistry — Posted on 2019-03-28

366 Resting networks and personality predict attack speed in social spiders

Hunt, E. R.; Mi, B.; Geremew, R.; Fernandez, C.; Wong, B. M.; Pruitt, J. N.; Pinter-Wollman, N.

10.1101/591453 — animal behavior and cognition — Posted on 2019-03-28

367 ETFL: A formulation for flux balance models accounting for expression, thermodynamics, and resource allocation constraints

SALVY, P.; Hatzimanikatis, V.

10.1101/590992 — systems biology — Posted on 2019-03-28

368 A general mathematical framework for understanding the behavior of heterogeneous stem cell regeneration

Lei, J.

10.1101/592139 — systems biology — Posted on 2019-03-28

369 Hierarchy of connectivity-function relationship of the human cortex revealed through predicting activity across functional domains

Wu, D.; Fan, L.; Song, M.; Wang, H.; Chu, C.; Yu, S.; Jiang, T.

10.1101/591776 — neuroscience — Posted on 2019-03-28

370 A sound-sensitive source of alpha oscillations in human non-primary auditory cortex

Billig, A. J.; Herrmann, B.; Rhone, A. E.; Gander, P. E.; Nourski, K. V.; Snoad, B. F.; Kovach, C. K.; Kawasaki, H.; Howard, M. A.; Johnsrude, I. S.

10.1101/590323 — neuroscience — Posted on 2019-03-28

371 Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

Acharya, S.; Mishra, A.; Paul, D.; Ansari, A. H.; Azhar, M.; Sharma, N.; Aich, M.; Sinha, D.; Sharma, S.; Jain, S.; Ray, A.; Maiti, S.; Chakraborty, D.

10.1101/591263 — molecular biology — Posted on 2019-03-28

372 Islet Gene View - a tool to facilitate islet research

Asplund, O.; Storm, P.; Ottosson-Laakso, E.; Krus, U.; Korsgren, O.; Mulder, H.; Renstrom, E.; Hansson, O.; Groop, L.; Prasad, R. B.

10.1101/435743 — molecular biology — Posted on 2019-03-28

373 Gut Microbiome Functional and Taxonomic Diversity within an Amazonian semi-nomadic hunter-gatherer group

Conteville, L. C.; Oliveira-Ferreira, J.; Vicente, A. C. P.

10.1101/590034 — microbiology — Posted on 2019-03-28

374 Shared genetic background between children and adults with attention deficit/hyperactivity disorder

Rovira, P.; Demontis, D.; Sanchez-Mora, C.; Zayats, T.; Klein, M.; Roth Mota, N.; Weber, H.; Garcia-Martinez, I.; Pagerols, M.; Vilar, L.; Arribas, L.; Richarte, V.; Corrales, M.; Fadeuilhe, C.; Bosch, R.; Espanol Martin, G.; Almos, P.; Doyle, A. E.; Grevet, E. H.; Grimm, O.; Halmoy, A.; Hoogman, M.; Hutz, M.; Jacob, C. P.; Kittel-Schneider, S.; Knappskog, P. M.; Lundervold, A.; Rivero, O.; Rovaris, D. L.; Salatino-Oliveira, A.; Santos da Silva, B.; Svirin, E.; Sprooten, E.; Strekalova, T.; ADHD Working Group of the Psychiatric Genomics Con, ; 23andMe Research team, ; Arias-Vasquez, A.; Sonu

10.1101/589614 — genetics — Posted on 2019-03-28

375 Single-molecule genome assembly of the Basket Willow, Salix viminalis, reveals earliest stages of sex chromosome expansion

Almeida, P.; Proux-Wera, E.; Churcher, A.; Soler, L.; Dainat, J.; Pucholt, P.; Nordlund, J.; Martin, T.; Rönnberg-Wästljung, A. C.; Nystedt, B.; Berlin, S.; Mank, J. E.

10.1101/589804 — evolutionary biology — Posted on 2019-03-28

376 Unifying Gene Duplication, Loss, and Coalescence on Phylogenetic Networks

Du, P.; Ogilvie, H.; Nakhleh, L.

10.1101/589655 — evolutionary biology — Posted on 2019-03-28

377 VIVA (VIsualization of VAriants): A VCF file visualization tool

Tollefson, G. A.; Schuster, J.; Gelin, F.; Ragavendran, A.; Restrepo, I.; Stey, P.; Padbury, J.; Uzun, A.

10.1101/589879 — bioinformatics — Posted on 2019-03-28

378 Deep convolutional neural networks for predicting the quality of single protein structural models

Hou, J.; Cao, R.; Cheng, J.

10.1101/590620 — bioinformatics — Posted on 2019-03-28

379 Exploration of interaction scoring criteria in the CANDO platform

Falls, Z.; Mangione, W.; Schuler, J.; Samudrala, R.

10.1101/591578 — bioinformatics — Posted on 2019-03-28

380 Osmolyte homeostasis controls single-cell growth rate and maximum cell size of Saccharomyces cerevisiae

Altenburg, T.; Goldenbogen, B.; Uhlendorf, J.; Klipp, E.

10.1101/586479 — systems biology — Posted on 2019-03-28

381 Identification of nitrogen-dependent QTL and underlying genes for root system architecture in hexaploid wheat

Griffiths, M. D.; Atkinson, J. A.; Gardiner, L.-J.; Swarup, R.; Pound, M. P.; Wilson, M. H.; Bennett, M. J.; Wells, D. M.

10.1101/591529 — plant biology — Posted on 2019-03-28

382 CELL SPECIFIC REACTIVATION OF EPICARDIUM AT THE ORIGIN OF FIBRO-FATTY REMODELING OF THE ATRIAL MYOCARDIUM

Suffee-Mosbah, N.; Moore-Morris, t.; Mougenot, n.; dilanaian, g.; berthet, m.; jagla, b.; Proukhnitzky, j.; leprince, p.; tregouet, d.; puceat, m.; hatem, s.

10.1101/589705 — pathology — Posted on 2019-03-28

383 Propagation of orientation selectivity in a spiking network model of layered primary visual cortex

Merkt, B.; Schuessler, F.; Rotter, S.

10.1101/425694 — neuroscience — Posted on 2019-03-28

384 Monovision and the misperception of motion

Burge, J.; Rodriguez-Lopez, V.; Dorronsoro, C.

10.1101/591560 — neuroscience — Posted on 2019-03-28

385 Specific Gut Microbiome Members are Associated with Distinct Immune Markers in Allogeneic Hematopoietic Stem Cell Transplantation

Masche, A. C.; Kielsen, K.; Cilieborg, M. S.; Lund, O.; Holmes, S.; Aarestrup, F. M.; Muller, K. G.; Pamp, S. J.

10.1101/590893 — microbiology — Posted on 2019-03-28

386 Discovery of ongoing selective sweeps within Anopheles mosquito populations using deep learning

Xue, A. T.; Schrider, D. R.; Kern, A. D.; Ag1000G Consortium,

10.1101/589069 — evolutionary biology — Posted on 2019-03-28

387 Apical transport of Crumbs maintains epithelial cell polarity

Aguilar-Aragon, M.; Fletcher, G.; Thompson, B. J.

10.1101/592311 — developmental biology — Posted on 2019-03-28

388 Quantification of biomolecular dynamics inside real and synthetic nuclear pore complexes using time-resolved atomic force microscopy

Stanley, G. J.; Akpinar, B.; Shen, Q.; Ellis Fisher, P. D.; Lusk, C. P.; Lin, C.; Hoogenboom, B.

10.1101/592303 — biophysics — Posted on 2019-03-28

389 Folate deficiency facilitates coordination of KDM6A with p53 in response to DNA damage

Gao, J.; Zou, J.; Li, J.; Zhang, Y.; Qiao, L.; Wang, F.; Bao, Y.; Hu, J.; Zhang, T.; Xie, Q.; Liu, C.

10.1101/591768 — bioinformatics — Posted on 2019-03-28

390 Inhibition of mTORC1 signaling in aged rats counteracts the decline in muscle mass and reverses multiple parameters of muscle signaling associated with sarcopenia

Joseph, G. A.; Wang, S.; Zhou, W.; Kimble, G.; Tse, H.; Eash, J. K.; Shavlakadze, T.; Glass, D. J.

10.1101/591891 — physiology — Posted on 2019-03-28

391 Rapid discovery of drug target engagement by isothermal shift assay

Webb, K. J.; Ball, K. A.; Coleman, S. J.; Jacobsen, J.; Stowell, M.; Old, W. M.

10.1101/584656 — pharmacology and toxicology — Posted on 2019-03-28

392 A Robust Model of Gated Working Memory

Strock, A.; Hinaut, X.; Rougier, N. P.

10.1101/589564 — neuroscience — Posted on 2019-03-28

393 Spectral Graph Theory of Brain Oscillations

Raj, A.; Cai, C.; Xie, X.; Palacios, E.; Owen, J.; Mukherjee, P.; Nagarajan, S.

10.1101/589176 — neuroscience — Posted on 2019-03-28

394 Rapid and iterative genome editing in the zoonotic malaria parasite Plasmodium knowlesi: New tools for P. vivax research

Mohring, F.; Hart, M. N.; Rawlinson, T. A.; Henrici, R.; Charleston, J. A.; Diez Benavente, E.; Patel, A.; Hall, J.; Almond, N.; Campino, S.; Clark, T. G.; Sutherland, C. J.; Baker, D. A.; Draper, S. J.; Moon, R. W.

10.1101/590976 — microbiology — Posted on 2019-03-28

395 Rhinovirus 2A is the predominant protease responsible for instigating the early block to gene expression encountered in infected cells

Smart, D.; Filippi, I.; Smalley, B.; Davies, D.; McCormick, C.

10.1101/591032 — microbiology — Posted on 2019-03-28

396 Effects of carbon nanotubes and derivatives of graphene oxide on soil bacterial diversity

Forstner, C.; Orton, T. G.; Wang, P.; Kopittke, P. M.; Dennis, P. G.

10.1101/591842 — microbiology — Posted on 2019-03-28

397 Gene content of the fish-hunting cone snail Conus consors

Andreson, R.; Roosaare, M.; Kaplinski, L.; Laht, S.; Koressaar, T.; Lepamets, M.; Brauer, A.; Kukushkina, V.; Remm, M.

10.1101/590695 — genomics — Posted on 2019-03-28

398 A Gene Co-expression Network-based Analysis of Multiple Brain Tissues Reveals Novel Genes and Molecular Pathways Underlying Major Depression

Gerring, Z. F.; Derks, E.; Major Depressive Disorder Working Group of the Psy, ; Gamazon, E.

10.1101/591693 — genetics — Posted on 2019-03-28

399 The p factor: Genetic analyses support a general dimension of psychopathology in childhood and adolescence

Allegrini, A. G.; Cheesman, R.; Rimfeld, K.; Selzam, S.; Pingault, J.-B.; Eley, T.; Plomin, R.

10.1101/591354 — genetics — Posted on 2019-03-28

400 Family aggregation analysis reveals a heritable background of equine grass sickness (dysautonomia)

Vincze, B.; Varga, M.; Gaspardy, A.; Kutasi, O.; Zenke, P.; Szenci, O.; Baska, F.; Bartels, A.; Spisak, S.; Solymosi, N.

10.1101/592253 — genetics — Posted on 2019-03-28

401 A triple-hybrid cross reveals new a hybrid incompatibility locus between D. melanogaster and D. sechellia

Cooper, J. C.; Guo, P.; Bladen, J.; Phadnis, N.

10.1101/590588 — evolutionary biology — Posted on 2019-03-28

402 Parasites Acquired Beta Satellite DNAs from Hominid Hosts via Horizontal Gene Transfer

Yang, J.; Zhou, Y.; Ma, G.; Zhang, X.; Guo, Y.

10.1101/589531 — evolutionary biology — Posted on 2019-03-28

403 Extreme heterogeneity in sex chromosome differentiation and dosage compensation in livebearers

Darolti, I.; Wright, A. E.; Sandkam, B. A.; Morris, J.; Bloch, N. I.; Farre, M.; Fuller, R. C.; Bourne, G. R.; Larkin, D. M.; Breden, F.; Mank, J. E.

10.1101/589788 — evolutionary biology — Posted on 2019-03-28

404 Sex allocation conflict and sexual selection throughout the lifespan of eusocial colonies

Avila, P.; Fromhage, L.; Lehmann, L.

10.1101/454512 — evolutionary biology — Posted on 2019-03-28

405 Phylogenetic inference of changes in amino acid propensities with single-position resolution

Klink, G. V.; Bazykin, G. A.

10.1101/589572 — evolutionary biology — Posted on 2019-03-28

406 Limits to Genomic Divergence Under Sexually Antagonistic Selection

Kasimatis, K. R.; Ralph, P. L.; Phillips, P. C.

10.1101/591610 — evolutionary biology — Posted on 2019-03-28

407 The effects of the neonicotinoid imidacloprid on gene expression and DNA methylation in the buff-tailed bumblebee Bombus terrestris

Bebane, P. S. A.; Hunt, B. J.; Pegoraro, M.; Jones, A. R. C.; Marshall, H.; Rosato, E.; Mallon, E. B.

10.1101/590091 — ecology — Posted on 2019-03-28

408 MASST: A Web-based Basic Mass Spectrometry Search Tool for Molecules to Search Public Data.

Wang, M.; Jarmusch, A. K.; Vargas, F.; Aksenov, A. A.; Gauglitz, J.; Weldon, K.; Petras, D.; da Silva, R.; Quinn, R.; Melnik, A.; van der Hooft, J. J. J.; Rodriguez, A. M. C.; Nothias, L. F.; Aceves, C. M.; Panitchpakdi, M.; Brown, E.; Di Ottavio, F.; Sikora, N.; Elijah, E. O.; Labarta-Bajo, L.; Gentry, E. G.; Shalapour, S.; Kyle, K. E.; Puckett, S. P.; Watrous, J. D.; Carpenter, C. S.; Bouslimani, A.; Ernst, M.; Swafford, A. D.; Zuniga, E. I.; Balunas, M. J.; Klassen, J. L.; Loomba, R.; Knight, R.; Bandeira, N.; Dorrestein, P. C.

10.1101/591016 — bioinformatics — Posted on 2019-03-28

409 TreeCluster: clustering biological sequences using phylogenetic trees

Balaban, M.; Moshiri, N.; Mai, U.; Mirarab, S.

10.1101/591388 — bioinformatics — Posted on 2019-03-28

410 PrankWeb: web server for ligand binding-site prediction and visualization

Jendele, L.; Krivak, R.; Skoda, P.; Novotny, M.; Hoksza, D.

10.1101/590877 — bioinformatics — Posted on 2019-03-28

411 A Cas9 nanoparticle system with truncated Cas9 target sequences on DNA repair templates enhances genome targeting in diverse human immune cell types

Nguyen, D. N.; Roth, T. L.; Li, J.; Chen, P. A.; Mamedov, M. M.; Vo, L. T.; Tobin, V.; Apathy, R.; Goodman, D.; Shifrut, E.; Bluestone, J. A.; Puck, J. M.; Szoka, F. C.; Marson, A.

10.1101/591719 — bioengineering — Posted on 2019-03-28

412 Moments reconstruction and local dynamic range compression of high order Superresolution optical fluctuation imaging

Yi, X.; Son, S.; Ando, R.; Miyawaki, A.; Weiss, S.

10.1101/500819 — bioengineering — Posted on 2019-03-28

413 Laminar Specific fMRI Reveals Directed Interactions in Distributed Networks During Language Processing

Sharoh, D.; van Mourik, T.; Bains, L. J.; Segaert, K.; Weber, K.; Hagoort, P.; Norris, D. G.

10.1101/585844 — neuroscience — Posted on 2019-03-28

414 Online sensory feedback during active search improves tactile localization

Fuchs, X.; Wulff, D. U.; Heed, T.

10.1101/590539 — neuroscience — Posted on 2019-03-28

415 Untangling intelligence, psychopathy, antisocial personality disorder, & conduct problems: A meta-analytic review

Sanchez de Ribera, O.; Kavish, N.; Katz, I.; Boutwell, B.

10.1101/100693 — neuroscience — Posted on 2019-03-28

416 Cultivating in situ triggers growth of previously uncultivated microorganisms via a growth initiation factor in nature

Jung, D.; Machida, K.; Nakao, Y.; Kindaichi, T.; Ohashi, A.; Aoi, Y.

10.1101/590653 — microbiology — Posted on 2019-03-28

417 Characterization of novel Chrysosporium morrisgordonii sp. nov., from bat white-nose syndrome (WNS) affected mines, northeastern United States

Zhang, T.; Ren, P.; Li, X.; Chaturvedi, S.; Chaturvedi, V.

10.1101/591503 — microbiology — Posted on 2019-03-28

418 CoBATCH for high-throughput single-cell epigenomic profiling

Wang, Q.; Xioong, H.; Ai, S.; Yu, X.; Liu, Y.; Zhang, J.; He, A.

10.1101/590661 — genomics — Posted on 2019-03-28

419 Functional genomics of a symbiotic community: shared traits in the olive fruit fly gut microbiota

Blow, F.; Gioti, A.; Goodhead, I. B.; Kalyva, M.; Kampouraki, A.; Vontas, J.; Darby, A. C.

10.1101/590489 — evolutionary biology — Posted on 2019-03-28

420 Predicting primary production in the southern California Current Ecosystem from chlorophyll, nutrient concentrations, and irradiance

Stukel, M.; Goericke, R.; Landry, M. R.

10.1101/590240 — ecology — Posted on 2019-03-28

421 Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility

Nishimura, K.; Dioguardi, E.; Nishio, S.; Villa, A.; Han, L.; Matsuda, T.; Jovine, L.

10.1101/591966 — biophysics — Posted on 2019-03-28

422 Reinforcement regulates timing variability in thalamus

Wang, J.; Hosseini, E.; Meirhaeghe, N.; Akkad, A.; Jazayeri, M.

10.1101/583328 — neuroscience — Posted on 2019-03-28

423 MiR-218: A Molecular Switch and Potential Biomarker of Susceptibility to Stress

Torres-Berrio, A.; Nouel, D.; Cuesta, S.; Parise, E. M.; Restrepo-Lozano, J. M.; Larochelle, P.; Nestler, E. J.; Flores, C.

10.1101/589325 — neuroscience — Posted on 2019-03-28

424 White Matter Extension of the Melbourne Children’s Regional Infant Brain Atlas: M-CRIB-WM

Yao, S. H. W.; Yang, J. Y.-M.; Alexander, B.; Wu, M. H.; Kelly, C. E.; Ball, G.; Seal, M. L.; Anderson, P. J.; Doyle, L. W.; Cheong, J. L. Y.; Spittle, A. J.; Thompson, D. K.

10.1101/590596 — neuroscience — Posted on 2019-03-28

425 Brain connectivity measures improve modeling of functional outcome after acute ischemic stroke

Ktena, S. I.; Schirmer, M.; Etherton, M. R.; Giese, A.-K.; Tuozzo, C.; Mills, B. B.; Rueckert, D.; Wu, O.; Rost, N. S.

10.1101/590497 — neuroscience — Posted on 2019-03-28

426 Damage to the Right Insula Disrupts the Perception of Affective Touch

Kirsch, L. P.; Besharati, S.; Papadaki, C.; Crucianelli, L.; Bertagnoli, S.; Ward, N.; Moro, V.; Jenkinson, P. M.; Fotopoulou, A.

10.1101/592014 — neuroscience — Posted on 2019-03-28

427 The complete chloroplast genome of Chinese medicine (Psoralea corylifolia Linn): Molecular Structures, Barcoding analysis, and Phylogenetic Analysis

Tan, W.; Gao, H.; Zhang, H.; Yu, X.; Tian, X.; Jiang, W.; Zhou, K.

10.1101/587758 — genomics — Posted on 2019-03-28

428 Genetic evaluation modeling of the Tunisian dairy cattle: assessment of the test-day model (TDM) and lactation model (L305) in accordance to the flock size

ressaissi, y.; Ben Hamouda, M.

10.1101/589523 — genetics — Posted on 2019-03-28

429 Divergent mitochondrial and nuclear OXPHOS genes are candidates for genetic incompatibilities in Ficedula Flycatchers

van der Heijden, E.; McFarlane, E.; van der Valk, T.; Qvarnstrom, A.

10.1101/588756 — evolutionary biology — Posted on 2019-03-28

430 Replicated anthropogenic hybridisations reveal parallel patterns of admixture in marine mussels.

Simon, A.; Arbiol, C.; Nielsen, E. E.; Couteau, J.; Sussarellu, R.; Burgeot, T.; Bernard, I.; Coolen, J. W. P.; Lamy, J.-B.; Robert, S.; Skazina, M.; Strelkov, P.; Queiroga, H.; Cancio, I.; Welch, J. J.; Viard, F.; Bierne, N.

10.1101/590737 — evolutionary biology — Posted on 2019-03-28

431 Estimating spatially and temporally complex range dynamics when detection is imperfect

Rushing, C.; Royle, J. A.; Ziolkowski, D. J.; Pardieck, K. L.

10.1101/586909 — ecology — Posted on 2019-03-28

432 A model of collective behavior based purely on vision

Bastien, R.; Romanczuk, P.

10.1101/589663 — animal behavior and cognition — Posted on 2019-03-28

433 Conformational gating in ammonia lyases

Lambrughi, M.; Sanader Marsic, Z.; Saez-Jimenez, V.; Mapelli, V.; Olsson, L.; Papaleo, E.

10.1101/583088 — biophysics — Posted on 2019-03-28

434 NanoDJ: A Dockerized Jupyter Notebook for Interactive Oxford Nanopore MinION Sequence Manipulation and Genome Assembly

Rodriguez-Perez, H.; Tamara, H.-B.; Lorenzo-Salazar, J. M.; Roda-Garcia, J. L.; Perez-Gonzalez, C. J.; Colebrook, M.; Flores, C.

10.1101/586842 — bioinformatics — Posted on 2019-03-28

435 Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2

Fred, S. M.; Laukkanen, L.; Vesa, L.; Goos, H.; Cardon, I.; Moliner, R.; Maritzen, T.; Varjosalo, M.; Casarotto, P. C.; Castren, E.

10.1101/591909 — pharmacology and toxicology — Posted on 2019-03-28

436 Precision timing with alpha-beta oscillatory coupling: stopwatch or motor control?

Kononowicz, T. W.; Sander, T.; Van Rijn, H.; van Wassenhove, V.

10.1101/591933 — neuroscience — Posted on 2019-03-28

437 Genotype 1 Japanese encephalitis virus predominates in nature in China

Shao, N.; Fu, S.; Li, F.; Zhang, W.; Wang, Q.; Lei, W.; He, Y.; Cao, Y.; liang, G.; Wang, H.

10.1101/591339 — molecular biology — Posted on 2019-03-28

438 Identification of pathogen genomic differences that impact human immune response and disease during Cryptococcus neoformans infection

Gerstein, A. C.; Jackson, K. M.; McDonald, T. R.; Wang, Y.; Lueck, B. D.; Bohjanen, S.; Smith, K. D.; Akampurira, A.; Meya, D. B.; Xue, C.; Boulware, D. R.; Nielsen, K.

10.1101/592212 — genetics — Posted on 2019-03-28

439 Spatio-temporal distribution of Spiroplasma infections in the tsetse fly (Glossina fuscipes fuscipes) in northern Uganda

Schneider, D. I.; Saarman, N.; Onyango, M. G.; Hyseni, C.; Opiro, R.; Echodu, R.; O'Neill, M.; Bloch, D.; Vigneron, A.; Johnson, T. J.; Dion, K.; Weiss, B. L.; Opiyo, E.; Caccone, A.; Aksoy, S.

10.1101/591321 — epidemiology — Posted on 2019-03-28

440 Heroin Type, Injecting Behavior, and HIV Transmission. A Simulation Model of HIV Incidence and Prevalence

Bobashev, G.; Mars, S.; Murphy, N.; Dreisbach, C.; Zule, W.; Ciccarone, D.

10.1101/591180 — epidemiology — Posted on 2019-03-28

441 Knowledge and awareness of cervical cancer in Southwestern Ethiopia is lacking: a descriptive analysis

Saleem, A.; Bekele, A.; Fitzpatrick, M. B.; Mahmoud, E. A.; Lin, A. W.; Velasco, H. E.; Rashed, M. M.

10.1101/592196 — epidemiology — Posted on 2019-03-28

442 Dietary acculturation of Asian and the Middle East and North African region immigrants to Saudi Arabia: healthy or unhealthy acquired nutritional behavior?

Al Zeidan, R.; Tharkar, S.; Hersi, A.; Ullah, A.

10.1101/591230 — epidemiology — Posted on 2019-03-28

443 Efficiency of protein synthesis inhibition depends on tRNA and codon compositions

Rudorf, S.

10.1101/592204 — cell biology — Posted on 2019-03-28

444 Facile assembly of an affordable miniature multicolor fluorescence microscope made of 3D-printed parts enables detection of single cells

Tristan-Landin, S. B.; Gonzalez-Suarez, A. M.; Jimenez-Valdes, R. J.; Garcia-Cordero, J. L.

10.1101/592170 — bioengineering — Posted on 2019-03-28

445 Nitro-fatty acids formation in Virgin Olive Oil during gastric digestion and its relationship to cultivar and fruit ripening

Sanchez-Calvo, B.; Mastrogiovanni, M.; Conde-Innamorato, P.; Arias-Sibillotte, M.; Trostchansky, A.; Rubbo, H.

10.1101/592147 — plant biology — Posted on 2019-03-28

446 Library preparation and sequencing platform introduces bias in metagenomics characterisation of microbial communities

Poulsen, C. S.; Aarestrup, F. M.; Ekstrom, C. T.; Pamp, S. J.

10.1101/592154 — microbiology — Posted on 2019-03-28

447 Isolation of lactic acid bacteria capable of reducing environmental alkyl and fatty acid hydroperoxides, and the effect of their oral administration on oxidative-stressed nematodes and rats

Watanabe, A.; Niimura, Y.; Yamaguchi, T.; Murota, K.

10.1101/592162 — microbiology — Posted on 2019-03-28

448 Multiscale analysis of acne connects molecular subnetworks with disease status

Hall, J. B.; Divaraniya, A. A.; Lee, H.-C.; Becker, C. E.; McCauley, B.; Glowe, P. K.; Sebra, R.; Pavel, A. B.; Singer, G.; Nelson, A.; Thiboutot, D.; Marmur, E.; Schadt, E. E.; Zeichner, J.; Guttman-Yassky, E.; Kidd, B. A.; Dudley, J. T.

10.1101/587857 — systems biology — Posted on 2019-03-28

449 Functional relevance of dual olfactory bulb in olfactory coding

Kuruppath, P.; Belluscio, L.

10.1101/588996 — neuroscience — Posted on 2019-03-28

450 Mechanics of DNA Replication and Transcription Guide the Asymmetric Distribution of RNAPol2 and New Nucleosomes on Replicated Daughter Genomes

Ziane, R.; Camasses, A.; Radman-Livaja, M.

10.1101/553669 — molecular biology — Posted on 2019-03-28

451 Single cell expression variability in highly homogeneous populations of human cells is widespread, is heritable, and implies cell function

Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J.

10.1101/574426 — genomics — Posted on 2019-03-28

452 Discovery of Hierarchical Representations for Efficient Planning

Tomov, M.; Yagati, S.; Kumar, A.; Yang, W.; Gershman, S.

10.1101/499418 — neuroscience — Posted on 2019-03-28

453 Predicting the occurrence of variants in RAG1 and RAG2

Lawless, D.; Lango Allen, H.; Thaventhiran, J.; Rare Diseases Consortium, N. B.; Hodel, F.; Fellay, J.; Walter, J. E.; Anwar, R.; Savic, S.

10.1101/272609 — genomics — Posted on 2019-03-28

454 Estimating prevalence for limb-girdle muscular dystrophy based on public sequencing databases

Liu, W.; Pajusalu, S.; Lake, N. J.; Zhou, G.; Ioannidis, N.; Mittal, P.; Johnson, N. E.; Weihl, C. C.; Williams, B. A.; Albrecht, D. E.; Rufibach, L. E.; Lek, M.

10.1101/502708 — epidemiology — Posted on 2019-03-28

455 Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC

Messerschmidt, C.; Obermayer, B.; Klinghammer, K.; Ochsenreither, S.; Treue, D.; Stenzinger, A.; Glimm, H.; Fröhling, S.; Kindler, T.; Brandts, C. H.; Schulze-Osthoff, K.; Weichert, W.; Tinhofer, I.; Klauschen, F.; Keilholz, U.; Beule, D.; Rieke, D. T.

10.1101/586396 — cancer biology — Posted on 2019-03-28

456 Synthetic 5 UTRs can either up- or down-regulate expression upon RBP binding

Katz, N.; Cohen, R.; Solomon, O.; Kaufmann, B.; Atar, O.; Yakhini, Z.; Goldberg, S.; Amit, R.

10.1101/174888 — synthetic biology — Posted on 2019-03-28

457 Enhancer-promoter association determines Sox2 transcription regulation in mouse pluripotent cells

Huang, L.; Li, Q.; Huang, Q.; Kong, S.; Zhu, X.; Peng, Y.; Zhang, Y.

10.1101/590745 — molecular biology — Posted on 2019-03-28

458 Decorating Microbially Produced Protein Nanowires with Peptide Ligands

Ueki, T.; Walker, D. J.; Tremblay, P.-L.; Nevin, K. P.; Ward, J. E.; Woodard, T. L.; Nonnenmann, S. S.; Lovley, D. R.

10.1101/590224 — synthetic biology — Posted on 2019-03-28

459 Metabolite sequestration enables rapid recovery from nutrient depletion

Hartline, C.; Mannan, A. A.; Zhang, F.; Oyarzun, D. A.

10.1101/590943 — systems biology — Posted on 2019-03-27

460 Feedback control promotes synchronisation of the cell-cycle across a population of yeast cells

Perrino, G.; Fiore, D.; Napolitano, S.; Galdi, F.; La Regina, A.; di Bernardo, M.; di Bernardo, D.

10.1101/590844 — synthetic biology — Posted on 2019-03-27

461 Phase space characterization for gene circuit design

Munoz Silva, M. A.; Matute, T.; Nunez, I.; Valdes, A.; Ruiz, C.; Vidal Pena, G.; Federici, F.; Rudge, T. J.

10.1101/590299 — synthetic biology — Posted on 2019-03-28

462 Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2+

Yong, J.; Bischof, H.; Siirin, M.; Murphy, A. N.; Malli, R.; Kaufman, R. J.

10.1101/591685 — cell biology — Posted on 2019-03-27

463 Macro-to-nano scale investigation of the acorn barnacle Semibalanus balanoides: correlative imaging, biological form and function, and bioinspiration

Mitchell, R. L.; Coleman, M.; Davies, P.; North, L.; Pope, E.; Pleydell-Pearce, C.; Harris, W.; Johnston, R.

10.1101/590158 — systems biology — Posted on 2019-03-27

464 Differential expression of the T cell inhibitor TIGIT in Glioblastoma and Multiple Sclerosis

Lucca, L. E.; Lerner, B. A.; DeBartolo, D.; Park, C.; Ponath, G.; Raddassi, K.; Hafler, D. A.; Pitt, D.

10.1101/591131 — immunology — Posted on 2019-03-27

465 Integration of pathway, cellular and genetic context reveals principles of synthetic lethality that affect reproducibility

Ku, A. A.; Kongara, S.; Hu, H.-M.; Zhao, X.; Wu, D.; McCormick, F.; Balmain, A.; Bandyopadhyay, S.

10.1101/591677 — cancer biology — Posted on 2019-03-27

466 Thermodynamic impacts of combinatorial mutagenesis on protein conformational stability: precise, high-throughput measurement by Thermofluor

Carter, C. W.; Weinreb, V.; Weinreb, G.; Chandrasekaran, S. N.; Das, J.; Dokholyan, N.

10.1101/591495 — biophysics — Posted on 2019-03-27

467 Addressable, \"Packet-Based\" Intercellular Communication through Plasmid Conjugation

Marken, J. P.; Murray, R. M.

10.1101/591552 — synthetic biology — Posted on 2019-03-27

468 Phospho-tuning immunity through Denisovan, modern human, and mouse TNFAIP3 gene variants

Zammit, N. W.; Siggs, O. M.; Gray, P.; Horikawa, K.; Daley, S. R.; Langley, D. B.; Cultrone, D.; Malle, E. K.; Walters, S. N.; Villanueva, J. E.; Warren, J.; Russell, A.; Cowley, M. J.; Gayevskiy, V.; Dinger, M. E.; Loetsch, C.; King, C.; Brink, R.; Zahra, D.; Chaudhri, G.; Karupiah, G.; Whittle, B.; Roots, C.; Bertram, E.; Yamada, M.; Jeelall, Y.; Enders, A.; Clifton, B. E.; Mabbitt, P. D.; Jackson, C. J.; Watson, S. R.; Jenne, C. N.; Lanier, L. L.; Wiltshire, T.; Spitzer, M. H.; Nolan, G. P.; Schmitz, F.; Aderem, A.; Porebski, B. T.; Buckle, A. M.; Abbott, D. W.; Ziegler, J. B.; Craig, M. E.

10.1101/589507 — immunology — Posted on 2019-03-27

469 The transcriptional regulator Id2 is critical for adipose-resident regulatory T cell differentiation, survival and function

Frias, A. B.; Hyzny, E. J.; Buechel, H. M.; Beppu, L.; Xie, B.; Jurczak, M. J.; D'Cruz, L. M.

10.1101/589994 — immunology — Posted on 2019-03-27

470 Seeing versus Knowing: The Temporal Dynamics of Real and Implied Colour Processing in the Human Brain

Teichmann, L.; Grootswagers, T.; Carlson, T.; Rich, A.

10.1101/369926 — neuroscience — Posted on 2019-03-27

471 Exposure to maternal obesity per se programs sex-differences in pancreatic islets of the offspring

Nicholas, L. M.; Nagao, M.; Kusinski, L. C.; Fernandez-Twinn, D. S.; Eliasson, L.; Ozanne, S. E.

10.1101/591586 — physiology — Posted on 2019-03-27

472 Computing Hubs in the Hippocampus and Cortex

Clawson, W. P.; Vicente, A. F.; Ferraris, M.; Bernard, C.; Battaglia, D.; Quilichini, P. P.

10.1101/513424 — neuroscience — Posted on 2019-03-27

473 Familiar neighbors, but not relatives, enhance fitness in a territorial mammal

Siracusa, E.; Boutin, S.; Dantzer, B.; Lane, J. E.; Coltman, D. W.; McAdam, A. G.

10.1101/589002 — evolutionary biology — Posted on 2019-03-27

474 VRmol: an Integrative Cloud-Based Virtual Reality System to Explore Macromolecular Structure

Xu, K.; Liu, N.; Xu, J.; Guo, C.; Zhao, L.; Wang, H.-w.; Zhang, Q. C.

10.1101/589366 — bioinformatics — Posted on 2019-03-27

475 Expression and distribution of Trophoblast Glycoprotein in the mouse retina

Wakeham, C. M.; Ren, G.; Morgans, C. W.

10.1101/590216 — neuroscience — Posted on 2019-03-27

476 Identification of PKCα-dependent phosphoproteins in mouse retina

Wakeham, C. M.; Wilmarth, P. A.; Cunliffe, J. M.; Klimek, J. E.; Ren, G.; David, L. L.; Morgans, C. W.

10.1101/589184 — neuroscience — Posted on 2019-03-27

477 Quantitative assessment of anti-gravity reflexes to evaluate vestibular dysfunction in rats

Martins-Lopes, V.; Bellmunt, A.; Greguske, E. A.; Maroto Ferrer, A. F.; Boadas-Vaello, P.; Llorens, J.

10.1101/590257 — neuroscience — Posted on 2019-03-27

478 Transcriptome-based prediction of complex traits in maize

Azodi, C.; Pardo, J.; VanBuren, R.; de los Campos, G.; Shiu, S.-H.

10.1101/587121 — genetics — Posted on 2019-03-27

479 The optimal discovery procedure for significance analysis of general gene expression studies

Bass, A. J.; Storey, J. D.

10.1101/571992 — bioinformatics — Posted on 2019-03-27

480 MCT4 is a high affinity transporter capable of exporting lactate in high-lactate environments

Contreras-Baeza, Y.; Sandoval, P. Y.; Alarcon, R.; Galaz, A.; Cortes-Molina, F.; Alegria, K.; Baeza-Lehnert, F.; Arce-Molina, R.; Guequen, A.; Flores, C. A.; San Martin, A. A.; Barros, L. F.

10.1101/586966 — physiology — Posted on 2019-03-27

481 Mammillothalamic disconnection alters hippocampo-cortical oscillatory activity and microstructure: Implications for diencephalic amnesia

Dillingham, C. M.; Milczarek, M. M.; Perry, J. C.; Frost, B. E.; Parker, G. D.; Assaf, Y.; Sengpiel, F.; O'Mara, S. M.; Vann, S.

10.1101/590901 — neuroscience — Posted on 2019-03-27

482 Heterogeneous profiles of coupled sleep oscillations in human hippocampus

Cox, R.; Ruber, T.; Staresina, B. P.; Fell, J.

10.1101/589978 — neuroscience — Posted on 2019-03-27

483 VarSight: Prioritizing Clinically Reported Variants with Binary Classification Algorithms

Holt, J. M.; Wilk, B.; Birch, C. L.; Brown, D. M.; Gajapathy, M.; Moss, A. C.; Sosonkina, N.; Wilk, M. A.; Anderson, J. A.; Harris, J. M.; Kelly, J. M.; Shaterferdosian, F.; Uno-Antonison, A. E.; Weborg, A.; Undiagnosed Diseases Network, ; Worthey, E. A.

10.1101/532440 — bioinformatics — Posted on 2019-03-27

484 Discrete and Continuous Cell Identities of the Adult Murine Striatum

Stanley, G.; Gokce, O.; Malenka, R. C.; Sudhof, T. C.; Quake, S. R.

10.1101/591396 — neuroscience — Posted on 2019-03-27

485 Orchestrating Single-Cell Analysis with Bioconductor

Amezquita, R. A.; Carey, V. J.; Carpp, L. N.; Geistlinger, L.; Lun, A. T.; Marini, F.; Rue-Albrecht, K.; Risso, D.; Soneson, C.; Waldron, L.; Pages, H.; Smith, M.; Huber, W.; Morgan, M.; Gottardo, R.; Hicks, S. C.

10.1101/590562 — genomics — Posted on 2019-03-27

486 APPLES: Distance-based Phylogenetic Placement for Scalable and Assembly-free Sample Identification

Balaban, M.; Sarmashghi, S.; Mirarab, S.

10.1101/475566 — bioinformatics — Posted on 2019-03-27

487 Freshwater Adaptation at the Molecular Scale in the Unique Sponges of Lake Baikal

Kenny, N. J.; Plese, B.; Riesgo, A.; Itskovich, V. B.

10.1101/416230 — zoology — Posted on 2019-03-27

488 Electroporation characteristics of human primary T cells

Aksoy, P.; Aksoy, B. A.; Czech, E.; Hammerbacher, J.

10.1101/466243 — immunology — Posted on 2019-03-27

489 Aboave-Weaire’s law in epithelia results from an angle constraint in contiguous polygonal lattices

Vetter, R.; Kokic, M.; Gomez, H.; Hodel, L.; Gjeta, B.; Iannini, A.; Villa-Fombuena, G.; Casares, F.; Iber, D.

10.1101/591461 — biophysics — Posted on 2019-03-27

490 Automated quantification of synaptic boutons reveals their 3D distribution in the insect mushroom body

Cabirol, A.; Haase, A.

10.1101/589770 — neuroscience — Posted on 2019-03-27

491 The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor

Coe, E. A.; Tan, J. Y.; Shapiro, M.; Louphrasitthiphol, P.; Bassett, A. R.; Marques, A. C.; Goding, C. R.; Vance, K. W.

10.1101/591065 — cancer biology — Posted on 2019-03-27

492 AMPK-independent LKB1 activity is required for efficient epithelial ovarian cancer metastasis

Buensuceso, A.; Ramos Valdes, Y.; DiMattia, G. E.; Shepherd, T.

10.1101/591073 — cancer biology — Posted on 2019-03-27

493 Hippo pathway effectors YAP1/TAZ induce a EWS-FLI1-opposing gene signature and associate with disease progression in Ewing Sarcoma

Rodriguez-Nunez, P.; Romero-Perez, L.; Amaral, A. T.; Puerto-Camacho, P.; Jordan, C.; Grunewald, T.; Marcilla, D.; de Alava, E.; Diaz-Martin, J.

10.1101/589648 — cancer biology — Posted on 2019-03-27

494 Molecular physiology of chemical defenses in a poison frog

Caty, S. N.; Alvarez-Buylla, A.; Byrd, G. D.; Vidoudez, C.; Roland, A. B.; Tapia, E. E.; Bodnik, B.; Trauger, S. A.; Coloma, L. A.; O'Connell, L. A.

10.1101/591115 — physiology — Posted on 2019-03-27

495 Detecting nanoscale distribution of protein pairs by proximity-dependent super-resolution microscopy

Lutz, T.; Kaufhold, W. T.; Clowsley, A. H.; Meletiou, A.; Di Michele, L.; Soeller, C.

10.1101/591081 — molecular biology — Posted on 2019-03-27

496 A conserved acidic cluster motif in SERINC5 confers resistance to antagonism by HIV-1 Nef

Stoneham, C.; Ramirez, P. W.; Singh, R.; Suarez, M.; Debray, A.; Lim, C.; Jia, X.; Xiong, Y.; Guatelli, J.

10.1101/590646 — microbiology — Posted on 2019-03-27

497 Minimisation of surface energy drives apical epithelial organisation and gives rise to Lewis’ law

Kokic, M.; Iannini, A.; Villa Fombuena, G.; Casares, F.; Iber, D.

10.1101/590729 — biophysics — Posted on 2019-03-27

498 A Chemical Probe of CARM1 Alters Epigenetic Plasticity against Breast Cancer Cell Invasion

Cai, X.-C.; Zhang, T.; Kim, E.-j.; Jiang, M.; Wang, K.; Wang, J.; Chen, S.; Zhang, N.; Wu, H.; Li, F.; dela Sena, C. C.; Zheng, H.; Vivcharuk, V.; Niu, X.; Zheng, W.; Lee, J. P.; Chen, Y.; Barsyte, D.; Szewczyk, M.; Hajian, T.; Ibanez, G.; Dong, A.; Dombrovsky, L.; Zhang, Z.; Deng, H.; Min, J.; Arrowsmith, C. H.; Mazutis, L.; Shi, L.; Vedadi, M.; Brown, P. J.; Xiang, J.; Qin, L.-X.; Xu, W.; Luo, M.

10.1101/591164 — biochemistry — Posted on 2019-03-27

499 Geochemical and metagenomic characterization of Jinata Onsen, a Proterozoic-analog hot spring, reveals novel microbial diversity including iron-tolerant phototrophs and thermophilic lithotrophs

Ward, L. M.; Idei, A.; Nakagawa, M.; Ueno, Y.; Fischer, W. W.; McGlynn, S. E.

10.1101/428698 — microbiology — Posted on 2019-03-27

500 Sumoylation regulates central spindle protein dynamics during chromosome segregation in oocyte

Pelisch, F.; Bel Borja, L.; Jaffray, E. G.; Hay, R. T.

10.1101/584763 — cell biology — Posted on 2019-03-27

501 Homology-guided re-annotation improves the gene models of the alloploid Nicotiana benthamiana

Kourelis, J.; Kaschani, F.; Grosse-Holz, F. M.; Homma, F.; Kaiser, M.; van der Hoorn, R. A. L.

10.1101/373506 — plant biology — Posted on 2019-03-27

502 Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and regulate behavioral odor discrimination

McLachlan, A. D.; Wong, J. Y. H.; Wan, B. A.; O'Kane, C. J.; Montagnese, M.; Zhang, S. W.; Masuda-Nakagawa, L. M.

10.1101/295659 — neuroscience — Posted on 2019-03-27

503 A likelihood-free estimator of population structure bridging admixture models and principal components analysis

Cabreros, I.; Storey, J. D.

10.1101/240812 — genomics — Posted on 2019-03-27

504 Unintended inhibition of protein function using GFP nanobodies in human cells

Kuey, C.; Larocque, G.; Clarke, N. I.; Royle, S. J.

10.1101/590984 — cell biology — Posted on 2019-03-27

505 Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases in parallel

Killoran, R. C.; Smith, M. J.

10.1101/577437 — biochemistry — Posted on 2019-03-27

506 Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress

Hanna, N.; Burdet, F.; Melotti, A.; Bosmani, C.; Kicka, S.; Hilbi, H.; Cosson, P.; Pagni, M.; Soldati, T.

10.1101/590810 — systems biology — Posted on 2019-03-27

507 Expression and distribution of Trophoblast Glycoprotein in the mouse retina

Wakeham, C. M.; Ren, G.; Morgans, C. W.

10.1101/590216 — neuroscience — Posted on 2019-03-27

508 Two accessory proteins govern MmpL3 mycolic acid transport in mycobacteria

Fay, A.; Czudnochowski, N.; Rock, J.; Johnson, J.; Krogan, N.; Rosenberg, O.; Glickman, M.

10.1101/581447 — microbiology — Posted on 2019-03-27

509 WHO child growth standards for Pygmies: one size fits all?

Fa, J. E.; Funk, S. M.; Guerra, B. P.; Ickowitz, A.; Poni, N. A.; Abdou, M. A.; Sibama, Y. H.; Penda, R.; Brull, G. R.; Abossolo, M.; Martin, E. A.; Okale, R.; Ze, B. A.; Carrion, A. M.; Sebastian, C. G.; de Loizaga Garcia, C. R.; Salazar, F. L.-R.; Amazia, H.; Reyes, I. A.; Exposito, R. S.

10.1101/591172 — scientific communication and education — Posted on 2019-03-27

510 The fungal endophyte Fusarium solani provokes differential effects on the energy balance of two Lotus species

Nieva, A. S.; Vilas, J. M.; Garriz, A.; Maiale, S. J.; Menendez, A. B.; Erban, A.; Kopka, J.; Ruiz, O. A.

10.1101/588400 — microbiology — Posted on 2019-03-27

511 M. leprae infects human keratinocytes via the interaction of laminin-5 with α-dystroglycan, integrin-β1, or -β4.

Jin, S.-H.; Kim, S.-K.; Lee, S.-B.

10.1101/591313 — microbiology — Posted on 2019-03-27

512 Rapidly increasing prevalence of overweight and obesity in older Ghanaian adults from 2007-2015: evidence from WHO-SAGE Waves 1 & 2

Lartey, S. T.; Magnussen, C. G.; Si, L.; Boateng, G. O.; de Graaff, B.; Biritwum, R. B.; Minicuci, N.; Kowal, P.; Blizzard, L.; Palmer, A. J.

10.1101/591222 — epidemiology — Posted on 2019-03-27

513 A systematic evaluation of neural morphology representations forcell type discrimination

Laturnus, S.; Kobak, D.; Berens, P.

10.1101/591370 — neuroscience — Posted on 2019-03-27

514 Effect of progesterone on Candida albicans biofilm formation under acidic conditions: a transcriptomic analysis

Goncalves, B.; Bernardo, R.; Wang, C.; Pedro, N.; Butler, G.; Azeredo, J.; Henriques, M.; Mira, N.; Silva, S.

10.1101/591347 — microbiology — Posted on 2019-03-27

515 Intermolecular interactions play a role in the distribution and transport of charged contrast agents in a cartilage model

Söderman, O.; Algotsson, J.; Jönsson, P.; Forsman, J.; Topgaard, D.

10.1101/591255 — biophysics — Posted on 2019-03-27

516 Bioactivity-guided isolation of rosmarinic acid as a principle bioactive compound from the butanol extract of Isodon rugosus against pea aphid, Acyrthosiphon pisum

Khan, S.; Taning, C. N. T.; Bonneure, E.; Mangelinckx, S.; Smagghe, G.; Ahmad, R.; Fatima, N.; Asif, M.; Shah, M. M.

10.1101/591271 — plant biology — Posted on 2019-03-27

517 Evaluation of the geographical utility of Eastern Russells viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity

Chaisakul, J.; Sookprasert, N.; Harrison, R. A.; Chaiyabutr, N.; Chanhome, L.; Casewell, N. R.

10.1101/591305 — pharmacology and toxicology — Posted on 2019-03-27

518 Multicenter preclinical studies as an innovative method to enhance translation: a systematic review of published studies

Hunniford, V. T.; Grudniewicz, A.; Fergusson, D. A.; Grigor, E.; Lansdell, C.; Lalu, M.

10.1101/591289 — epidemiology — Posted on 2019-03-27

519 Viral infection overcomes ineffectiveness of anti-tumoral CD8+ T cell mediated cytotoxicity

Zhou, F.; Kardash, J.; Bhat, H.; Duhan, V.; Friedrich, S.; Bezgovsek, J.; Kalkavan, H.; Bergerhausen, M.; Schiller, M.; Machlah, Y.; Brandenburg, T.; Hardt, C.; Krolik, M.; Flatz, L.; Lang, P.; Lang, K.

10.1101/591198 — immunology — Posted on 2019-03-27

520 Ethanolic extract of Ocimum sanctum leaves reduced invasion and matrix metalloproteinase activity of head and neck cancer cell lines

Utispan, K.; Niyomtham, N.; Yingyongnarongkul, B.-e.; Koontongkaew, S.

10.1101/591214 — cancer biology — Posted on 2019-03-27

521 Properties of individual hippocampal synapses influencing NMDA-receptor activation by spontaneous neurotransmission.

Metzbower, S. R.; Joo, Y.; Benavides, D. R.; Blanpied, T. A.

10.1101/590141 — neuroscience — Posted on 2019-03-27

522 The WT1-like transcription factor Klumpfuss maintains lineage commitment in the intestine

Korzelius, J.; Ronnen-Oron, T.; Baldauf, M.; Meier, E.; Sousa-Victor, P.; Jasper, H.

10.1101/590885 — developmental biology — Posted on 2019-03-27

523 Structural determinants of microtubule minus end preference in CAMSAP CKK domains

Atherton, J.; Luo, Y.; Xiang, S.; Yang, C.; Jiang, K.; Stangier, M.; Vemu, A.; Cook, A. D.; Wang, S.; Roll-Mecak, A.; Steinmetz, M. O.; Akhmanova, A.; Baldus, M.; Moores, C.

10.1101/586230 — biophysics — Posted on 2019-03-27

524 The structure of an injectisome export gate demonstratesconservation of architecture in the core export gatebetween flagellar and virulence type three secretionsystems

Johnson, S.; Kuhlen, L.; Deme, J.; Abrusci, P.; Lea, S. M.

10.1101/590273 — biochemistry — Posted on 2019-03-27

525 Contribution of PSD-95 protein to reward location memory

Caly, A.; Sliwinska, M.; Ziolkowska, M.; Lukasiewicz, K.; Pagano, R.; Nowacka, A.; Borczyk, M.; Radwanska, K.

10.1101/590109 — neuroscience — Posted on 2019-03-27

526 Identification of PKC -dependent phosphoproteins in mouse retina

Wakeham, C. M.; Wilmarth, P. A.; Cunliffe, J. M.; Klimek, J. E.; Ren, G.; David, L. L.; Morgans, C. W.

10.1101/589184 — neuroscience — Posted on 2019-03-27

527 Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules

Rodriguez-Garcia, R.; Volkov, V. A.; Chen, C.-Y.; Katrukha, E. A.; Olieric, N.; Aher, A.; Grigoriev, I.; Preciado Lopez, M.; Steinmetz, M. O.; Kapitein, L. C.; Koenderink, G.; Dogterom, M.; Akhmanova, A.

10.1101/590869 — cell biology — Posted on 2019-03-27

528 A Synergistic Anti-Cancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical-Genetic High Content Phenotypic Screen

Dawson, J. C.; Serrels, B.; Byron, A.; Muir, M.; Makda, A.; Garcia-Munoz, A.; von Kriegsheim, A.; Carragher, N. O.; Frame, M. C.

10.1101/590802 — cancer biology — Posted on 2019-03-27

529 Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule

Lacey, S. E.; He, S.; Scheres, S. H. W.; Carter, A. P.

10.1101/590786 — molecular biology — Posted on 2019-03-27

530 Single chromosome gains can function as metastasis suppressors and metastasis promoters

Vasudevan, A.; Baruah, P. S.; Smith, J. C.; Wang, Z.; Sayles, N. M.; Andrews, P.; Kendall, J.; Chunduri, N. K.; Levy, D.; Wigler, M.; Storchova, Z.; Sheltzer, J. M.

10.1101/590547 — cancer biology — Posted on 2019-03-27

531 Observing an antisense drug complex in intact human cells by in-cell NMR

Schlagnitweit, J.; Sandoz, S. F.; Jaworski, A.; Guzzetti, I.; Aussenac, F.; Carbajo, R. J.; Chiarparin, E.; Pell, A. J.; Petzold, K.

10.1101/589812 — biophysics — Posted on 2019-03-27

532 Cell signalling stabilizes morphogenesis against noise

Hagolani, P.; Zimm, R.; Marin-Riera, M.; Salazar-Ciudad, I.

10.1101/590794 — developmental biology — Posted on 2019-03-27

533 Detection and characterization of apoptotic and necrotic cell death by time-lapse quantitative phase image analysis

Vicar, T.; Raudenska, M.; Gumulec, J.; Masarik, M.; Balvan, J.

10.1101/589697 — cell biology — Posted on 2019-03-27

534 Identification of a human adult cardiac stem cell population with neural crest origin

Höving, A. L.; Merten, M.; Schmidt, K. E.; Faust, I.; Ruiz-Perera, L. M.; Hachmeister, H.; Sommer, S.-P.; Fujita, B.; Pühler, T.; Huser, T.; Greiner, J. F. W.; Kaltschmidt, B.; Gummert, J.; Knabbe, C.; Kaltschmidt, C.

10.1101/590679 — cell biology — Posted on 2019-03-27

535 Volumetric two-photon imaging in live cells and embryos via axially gradient excitation

Gao, Y.; Xia, X.; Yu, J.; Chen, T.; Xu, Z.; Xiao, L.; Wang, L.; Yan, F.; Du, Z.; Chu, J.; Zheng, H.; Li, H.; Zheng, W.

10.1101/589317 — bioengineering — Posted on 2019-03-27

536 Using the past to estimate sensory uncertainty

Beierholm, U.; Rohe, T.; Ferrari, A.; Stegle, O.; Noppeney, U.

10.1101/589275 — neuroscience — Posted on 2019-03-27

537 Speciation with gene flow across an elevational gradient in New Guinea kingfishers

Linck, E.; Freeman, B. G.; Dumbacher, J. P.

10.1101/589044 — evolutionary biology — Posted on 2019-03-27

538 A chemical counterpunch: Chromobacterium violaceum ATCC31532 produces violacein in response to translation-inhibiting antibiotics

Lozano, G. L.; Guan, C.; Cao, Y.; Borlee, B. R.; Broderick, N. A.; Stabb, E. V.; Handelsman, J.

10.1101/589192 — microbiology — Posted on 2019-03-27

539 Consequences of consumer origin and omnivory on stability in experimental food web modules

Granados, M.; Pagnucco, K. S.; Ricciardi, A.

10.1101/589259 — ecology — Posted on 2019-03-27

540 VRmol: an Integrative Cloud-Based Virtual Reality System to Explore Macromolecular Structure

Xu, K.; Liu, N.; Xu, J.; Guo, C.; Zhao, L.; Wang, H.-w.; Zhang, Q. C.

10.1101/589366 — bioinformatics — Posted on 2019-03-27

541 Cardiac structure and function in patients with schizophrenia taking antipsychotic drugs: an MRI study

Pillinger, T.; Osimo, E.; de Marvao, A.; Berry, A.; Whitehurst, T.; Statton, B.; Quinlan, M.; Brugger, S.; Vazir, A.; Cook, S.; O'Regan, D.; Howes, O.

10.1101/589093 — physiology — Posted on 2019-03-27

542 Ray tracing 3D spectral scenes through human optics models

Lian, T.; MacKenzie, K. J.; Brainard, D. H.; Cottaris, N. P.; Wandell, B. A.

10.1101/589234 — neuroscience — Posted on 2019-03-27

543 Direct and transgenerational effects of an experimental heat wave on early life stages in a freshwater snail

Leicht, K.; Seppala, O.

10.1101/449777 — ecology — Posted on 2019-03-27

544 Dual RNA-Seq meta-analysis in Plasmodium infection

Mukherjee, P.; Heitlinger, E.

10.1101/576116 — bioinformatics — Posted on 2019-03-27

545 No evidence that portion size influences food consumption in male Sprague Dawley rats

Naneix, F.; Pinder, S. C.; Summers, M. Y.; Rouleau, R. M.; Robinson, E.; Myers, K. P.; McCutcheon, J. E.

10.1101/524272 — animal behavior and cognition — Posted on 2019-03-27

546 False-positive neuroimaging: Undisclosed flexibility in testing spatial hypotheses allows presenting anything as a replicated finding

Hong, Y.; Yoo, Y.; Han, J.; Wager, T.; Woo, C.-W.

10.1101/514521 — neuroscience — Posted on 2019-03-27

547 Target of selective auditory attention can be robustly followed with MEG

Kurmanaviciute, D.; Rantala, A.; Jas, M.; Valila, A.; Parkkonen, L.

10.1101/588491 — neuroscience — Posted on 2019-03-27

548 Clinical, imaging genetics and deformation based morphometry study of longitudinal changes after surgery for intractable aggressive behaviour

Venetucci Gouveia, F.; Germann, J.; Campelo Borba de Morais, R. M.; Talamoni Fonoff, E.; Hamani, C.; Alho, E. J.; Brentani, H.; Martins, A. P.; Devenyi, G. A.; Patel, R.; Steele, C. J.; Gramer, R.; Chakravarty, M. M.; Chacon Ruiz Martinez, R.

10.1101/548826 — clinical trials — Posted on 2019-03-27

549 Detailed analysis of paternal knockout Grb10 mice suggests effects on stability of social behavior, rather than social dominance

Rienecker, K.; Chavasse, A.; Moorwood, K.; Ward, A.; Isles, A.

10.1101/493692 — animal behavior and cognition — Posted on 2019-03-27

550 Human Foveal Cone Photoreceptor Topography and its Dependence on Eye Length

Wang, Y.; Bensaid, N.; Tiruveedhula, P.; Ma, J.; Ravikumar, S.; Roorda, A.

10.1101/589135 — neuroscience — Posted on 2019-03-27

551 Cortical changes associated with parenthood are present in late life

Orchard, E. R.; Ward, P. G. D.; Sforazzini, F.; Storey, E.; Egan, G. F.; Jamadar, S. D.

10.1101/589283 — neuroscience — Posted on 2019-03-27

552 Host porphobilinogen deaminase deficiency confers malaria resistance in Plasmodium chabaudi but not in Plasmodium falciparum or Plasmodium berghei during intraerythrocytic growth

Schnider, C. B.; Yang, H.; Starrs, L.; Ehmann, A.; Rahimi, F.; Di Pierro, E.; Graziadei, G.; Matthews, K.; de Koning-Ward, T.; Bauer, D. C.; Foote, S.; McMorran, B.; Burgio, G.

10.1101/589242 — microbiology — Posted on 2019-03-27

553 Transcriptomic analysis of insecticide resistance in the lymphatic filariasis vector Culex quinquefasciatus

Silva Martins, W. F.; Wilding, C. S.; Isaacs, A. T.; Rippon, E. J.; Megy, K.; Donnelly, M. J.

10.1101/589028 — genomics — Posted on 2019-03-27

554 Effect of READ1 on latent profiles of reading disability and comorbid attention and language learning disability subtypes

Li, M.; Truong, D.; DeMille, M.; Malins, J.; Lovett, M.; Bosson-Heenan, J.; Gruen, J. R.; Frijters, J.

10.1101/589226 — genetics — Posted on 2019-03-27

555 A test of the evolution of increased competitive ability in two invaded regions

Rotter, M.; Vallejo-Marin, M.; Holeski, L. M.

10.1101/589143 — ecology — Posted on 2019-03-27

556 Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells

Sachdev, S.; Boyd, R.; Grimsey, N. L.; Connor, M.

10.1101/589341 — pharmacology and toxicology — Posted on 2019-03-27

557 From acoustic to linguistic analysis of temporal speech structure: acousto-linguistic transformation during speech perception using speech quilts.

Overath, T.; Paik, J. H.

10.1101/589010 — neuroscience — Posted on 2019-03-27

558 Comparative genomic analysis of three salmonid species identifies functional candidate genes involved in resistance to the intracellular bacteria Piscirickettsia salmonis

Yanez, J. M.; Yoshida, G. M.; Parra, A.; Correa, K.; Barria, A.; Bassini, L. N.; Christensen, K. A.; Lopez, M. E.; Carvalheiro, R.; Lhorente, J. P.; Pulgar, R.

10.1101/589200 — genomics — Posted on 2019-03-27

559 Trans-membrane association of the Sec and BAM complexes for bacterial outer-membrane biogenesis

Alvira-de-Celis, S.; Watkins, D. W.; Troman, L.; Lorriman, J.; Daum, B.; Gold, V. A. M.; Collinson, I.

10.1101/589077 — biochemistry — Posted on 2019-03-27

560 Knowledge of Chagas disease in Latin American migrant population living in Japan and factors associated with knowledge level

Iglesias-Rodriguez, I. M.; Mizukami, S.; Manh, D. H.; Thuan, T. M.; Justiniano, H. A.; Miura, S.; Ito, G.; Huy, N. T.; Hirayama, K.

10.1101/589051 — scientific communication and education — Posted on 2019-03-27

561 The haploinsufficient tumor suppressor Tip60 negatively regulates the oncogenic Aurora B kinase

Bose, A.; Sudevan, S.; Rao, V. J.; Shima, H.; Igarashi, K.; Kundu, T. K.

10.1101/589473 — biochemistry — Posted on 2019-03-27

562 Genome-wide association study of Parkinsons disease progression biomarkers in 12 longitudinal patients cohorts

Iwaki, H.; Blauwendraat, C.; Leonard, H. L.; Kim, J. J.; Liu, G.; Maple-Grodem, J.; Corvol, J.-C.; Pihlstrom, L.; van Nimwegen, M.; Hutten, S. J.; Khanh-Dung, H. N.; Rick, J.; Eberly, S.; Faghri, F.; Auinger, P.; Scott, K. M.; Wijeyekoon, R.; Van Deerlin, V. M.; Hernandez, D. G.; Gibbs, J. R.; Chitrala, K. N.; Day-Williams, A. G.; Brice, A.; Alves, G.; Noyce, A. J.; Tysnes, O.-B.; Evans, J. R.; Breen, D. P.; Estrada, K.; Wegel, C. E.; Danjou, F.; Simon, D. K.; Andreassen, O.; Ravina, B.; Toft, M.; Heutink, P.; Bloem, B. R.; Weintraub, D.; Barker, R. A.; Williams-Gray, C. H.; van de Warrenburg,

10.1101/585836 — genetics — Posted on 2019-03-27

563 Consciousness as a Concrete Physical Phenomenon

Jylkka, J.; Railo, H.

10.1101/557561 — neuroscience — Posted on 2019-03-27

564 Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

Kumar, V.; Doharey, P. K.; Gulati, S.; Meehan, J.; Martinez, M. G.; Hughes, K.; Mooers, B. H. M.; Cruz-Reyes, J.

10.1101/524702 — molecular biology — Posted on 2019-03-27

565 Zika Virus Subverts Stress Granules to Promote and Restrict Viral Gene Expression

Bonenfant, G.; Williams, N.; Netzband, R.; Schwarz, M.; Evans, M. J.; Pager, C. T.

10.1101/436865 — microbiology — Posted on 2019-03-27

566 Molecular evolution of non-fertilizing sperm in Lepidoptera suggests minimal direct involvement in sperm competition

Mongue, A. J.; Hansen, M. E.; Gu, L.; Sorenson, C. E.; Walters, J. R.

10.1101/404236 — evolutionary biology — Posted on 2019-03-27

567 Emergence and suppression of cooperation by action visibility in transparent games

Unakafov, A. M.; Schultze, T.; Kagan, I.; Gail, A.; Moeller, S.; Eule, S.; Wolf, F.

10.1101/314500 — evolutionary biology — Posted on 2019-03-27

568 hicap: in silico serotyping of the Haemophilus influenzae capsule locus

Watts, S. C.; Holt, K. E.

10.1101/543454 — bioinformatics — Posted on 2019-03-27

569 Strengths and potential pitfalls of hay-transfer for ecological restoration revealed by RAD-seq analysis in floodplain Arabis species

Dittberner, H.; Becker, C.; Jiao, W.-B.; Schneeberger, K.; Hoelzel, N.; Tellier, A.; de Meaux, J.

10.1101/474858 — ecology — Posted on 2019-03-27

570 The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus infectivity

Hasan, M.; Parmar, R.; Liang, Q.; Qiu, H.; Tiwari, V.; Sharp, J.; Wang, L.; Tandon, R.

10.1101/590463 — microbiology — Posted on 2019-03-26

571 Transcriptome-based prediction of complex traits in maize

Azodi, C.; Pardo, J.; VanBuren, R.; de los Campos, G.; Shiu, S.-H.

10.1101/587121 — genetics — Posted on 2019-03-26

572 Modeling the growth of organisms validates a general relation between metabolic costs and natural selection

Ilker, E.; Hinczewski, M.

10.1101/358440 — evolutionary biology — Posted on 2019-03-26

573 Correlating Synaptic Ultrastructure and Function at the Nanoscale

Maus, L.; Altas, B.; Rhee, J.; Brose, N.; Imig, C.; Cooper, B. H.

10.1101/588848 — neuroscience — Posted on 2019-03-26

574 Shared and distinct genetic risk factors for childhood onset and adult onset asthma: genome- and transcriptome-wide Studies

Pividori, M.; Schoettler, N.; Nicolae, D. L.; Ober, C.; Im, H. K.

10.1101/427427 — genetics — Posted on 2019-03-26

575 Impact of initial protein stability on local fitness landscapes

Faber, M. S.; Wrenbeck, E. E.; Azouz, L. R.; Steiner, P. J.; Whitehead, T. A.

10.1101/590398 — evolutionary biology — Posted on 2019-03-26

576 A Polybasic Domain in aPKC Mediates Par-6-Dependent Control of Plasma Membrane Targeting and Kinase Activity

Hong, Y.; Dong, W.; Lu, J.; Zhang, X.; Wu, Y.; Lettieri, K.; Hammond, G.

10.1101/588624 — cell biology — Posted on 2019-03-26

577 Electroporation characteristics of human primary T cells

Aksoy, P.; Aksoy, B. A.; Czech, E.; Hammerbacher, J.

10.1101/466243 — immunology — Posted on 2019-03-26

578 Development and Application of a Tri-allelic PCR Assay for Screening Vgsc-L1014F Kdr Mutations Associated with Pyrethroid and Organochlorine Resistance in the Mosquito Culex quinquefasciatus

Silva Martins, W. F.; Silva Pereira, B. N.; Vieira Alves, A. T.; Murphy, A.; Silva Martins, P. G.; Weetman, D.; Wilding, C. S.; Donnelly, M. J.

10.1101/588905 — genetics — Posted on 2019-03-26

579 Familiar neighbors, but not relatives, enhance fitness in a territorial mammal

Siracusa, E.; Boutin, S.; Dantzer, B.; Lane, J. E.; Coltman, D. W.; McAdam, A. G.

10.1101/589002 — evolutionary biology — Posted on 2019-03-26

580 tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing

Krause, M.; Niazi, A. M.; Labun, K.; Müller, F. S.; Torres Cleuren, Y. N.; Valen, E.

10.1101/588343 — bioinformatics — Posted on 2019-03-26

581 Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells

Robinson, B. A.; Van Winkle, J. A.; McCune, B. T.; Peters, A. M.; Nice, T. J.

10.1101/372615 — microbiology — Posted on 2019-03-26

582 Application of Volumetric Absorptive Micro Sampling to Measure Multidimensional Anti-Influenza Hemagglutinin IgG Antibodies by mPlex-Flu Assay

Wang, J.; Li, D.; Wiltse, A.; Emo, J.; Hilchey, S. P.; Zand, M. S.

10.1101/588038 — immunology — Posted on 2019-03-26

583 Development of a drug repressible β-catenin mutant mouse to examine effect of activated β-catenin signaling on long-term maintenance of mammary tumor growth

Gorman, J. L.; Adams, J. R.; Jones, E. M.; Egan, S. E.; Woodgett, J. R.

10.1101/588459 — cancer biology — Posted on 2019-03-26

584 Denoising of Aligned Genomic Data

Fischer-Hwang, I.; Ochoa, I.; Weissman, T.; Hernaez, M.

10.1101/590372 — bioinformatics — Posted on 2019-03-26

585 Estimation of mutual information for real-valued data with error bars and controlled bias

Holmes, C. M.; Nemenman, I.

10.1101/589929 — bioinformatics — Posted on 2019-03-26

586 Quantitatively predicting optimal antibiotic dose levels from drug-target binding

Clarelli, F.; Palmer, A.; Singh, B.; Storflor, M.; Lauksund, S.; Cohen, T.; Abel, S.; Abel zur Wiesch, P.

10.1101/369975 — biochemistry — Posted on 2019-03-26

587 Hippocampal-midbrain circuit enhances the pleasure of anticipation in the prefrontal cortex

Iigaya, K.; Hauser, T. U.; Kurth-Nelson, Z.; O'Doherty, J. P.; Dayan, P.; Dolan, R. J.

10.1101/588699 — neuroscience — Posted on 2019-03-26

588 Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation

Selewa, A.; Dohn, R.; Eckart, H.; Lozano, S.; Xie, B.; Gauchat, E.; Elorbany, R.; Rhodes, K.; Burnett, J.; Gilad, Y.; Pott, S.; Basu, A.

10.1101/585901 — genomics — Posted on 2019-03-26

589 A logical model of homology for comparative biology

Mabee, P.; Balhoff, J.; Dahdul, W.; Lapp, H.; Mungall, C.; Vision, T.

10.1101/588822 — evolutionary biology — Posted on 2019-03-26

590 Dual RNA-Seq meta-analysis in Plasmodium infection

Mukherjee, P.; Heitlinger, E.

10.1101/576116 — bioinformatics — Posted on 2019-03-26

591 Easily adaptable head-free training system of macaques for tasks requiring precise measurements of eye position

Kawaguchi, K.; Pourriahi, P.; Seillier, L.; Clery, S.; Nienborg, H.

10.1101/588566 — neuroscience — Posted on 2019-03-26

592 Reward revaluation biases hippocampal replay content away from the preferred outcome

Carey, A. A.; Tanaka, Y.; van der Meer, M.

10.1101/397950 — neuroscience — Posted on 2019-03-26

593 Unique Trophoblast Chromatin Environment Mediated by the PcG Protein SFMBT2

Tang, P.; Miri, K.; Varmuza, S.

10.1101/590356 — genomics — Posted on 2019-03-26

594 The convergent evolution of eusociality is based on a shared reproductive groundplan plus lineage-specific sets of plastic genes

Warner, M. R.; Qiu, L.; Holmes, M. J.; Mikheyev, A. S.; Linksvayer, T. A.

10.1101/454645 — evolutionary biology — Posted on 2019-03-26

595 Selection and gene flow shape niche-associated copy-number variation of pheromone receptor genes

Lee, D.; Zdraljevic, S.; Cook, D. E.; Frezal, L.; Hsu, J.-C.; Sterken, M. G.; Riksen, J. A. G.; Wang, J.; Kammenga, J. E.; Braendle, C.; Felix, M.-A.; Schroeder, F. C.; Andersen, E. C.

10.1101/580803 — evolutionary biology — Posted on 2019-03-26

596 The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs

Marchant, A.; Cisneros, A.; Dube, A. K.; Gagnon-Arsenault, I.; Ascencio, D.; Jain, H.; Aube, S.; Eberlein, C.; Evans-Yamamoto, D.; Yachie, N.; Landry, C. R.

10.1101/564401 — evolutionary biology — Posted on 2019-03-26

597 Tetraploidy in rodent cardiac stem cells confers enhanced biological properties

Broughton, K.; Khieu, T.; Nguyen, N.; Rosa, M.; Mohsin, S.; Quijada, P.; Wang, J.; Echeagaray, O.; Kubli, D.; Kim, T.; Firouzi, F.; Monsanto, M.; Gude, N.; Adamson, R.; Dembitsky, W.; Davis, M.; Sussman, M.

10.1101/521716 — cell biology — Posted on 2019-03-26

598 Automatic structure-based NMR methyl resonance assignment in large proteins

Pritisanac, I.; Würz, J. M.; Alderson, T. R.; Güntert, P.

10.1101/538272 — biophysics — Posted on 2019-03-26

599 scAlign: a tool for alignment, integration and rare cell identification from scRNA-seq data

Johansen, N.; Quon, G.

10.1101/504944 — bioinformatics — Posted on 2019-03-26

600 ntEdit: scalable genome sequence polishing

Warren, R. L.; Coombe, L.; Mohamadi, H.; Zhang, J.; Jaquish, B.; Isabel, N.; Jones, S. J.; Bousquet, J.; Bohlmann, J.; Birol, I.

10.1101/565374 — bioinformatics — Posted on 2019-03-26

601 Action enhances perception: Visually evoked neural responses are enhanced when engaging in a motor task

Ki, J. J.; Parra, L. C.; Dmochowski, J.

10.1101/588806 — neuroscience — Posted on 2019-03-26

602 Structure of a Tc holotoxin pore provides insights into the translocation mechanism

Roderer, D.; Hofnagel, O.; Benz, R.; Raunser, S.

10.1101/590430 — molecular biology — Posted on 2019-03-26

603 Moving microbes: the dynamics of transient microbial residence on human skin

Vandegrift, R.; Fahimipour, A. K.; Muscarella, M.; Bateman, A. C.; Van Den Wymelenberg, K.; Bohannan, B.

10.1101/586008 — microbiology — Posted on 2019-03-26

604 CD16-158-VALINE CHIMERIC RECEPTOR T CELLS OVERCOME THE RESISTANCE OF KRAS-MUTATED COLORECTAL CARCINOMA CELLS TO CETUXIMAB

Arriga, R.; Caratelli, S.; Lanzilli, G.; Ottaviani, A.; Cenciarelli, C.; Sconocchia, T.; Spagnoli, G. C.; Iezzi, G.; Roselli, M.; Lauro, D.; Dotti, G.; Ferrone, S.; Sconocchia, G.

10.1101/588525 — immunology — Posted on 2019-03-26

605 Splicing conservation signals in plant long non-coding RNAs

Corona-Gomez, J. A.; Garcia-Lopez, I. J.; Stadler, P. F.; Fernandez-Valverde, S. L.

10.1101/588954 — genomics — Posted on 2019-03-26

606 Food Webs: Insights from a General Ecosystem Model

Flores, C.; Kortsch, S.; Tittensor, D. P.; Harfoot, M.; Purves, D.

10.1101/588665 — ecology — Posted on 2019-03-26

607 NatB modulates Rb mutant cell death and tumor growth by regulating EGFR/MAPK signaling through the N-end rule pathways

Sheng, Z.; Du, W.

10.1101/590349 — cell biology — Posted on 2019-03-26

608 Model-based tumor subclonal reconstruction

Caravagna, G.; Heide, T.; Williams, M.; Zapata, L.; Nichol, D.; Chkhaidze, K.; Cross, W. H.; Cresswell, G. D.; Werner, B.; Acar, A.; Barnes, C. P.; Sanguinetti, G.; Graham, T. A.; Sottoriva, A.

10.1101/586560 — bioinformatics — Posted on 2019-03-26

609 Depletion of resident muscle stem cells inhibits muscle fiber hypertrophy induced by lifelong physical activity

Englund, D.; Murach, K.; Dungan, C.; Figueiredo, V.; Vechetti, I.; Dupont-Versteegden, E.; McCarthy, J.; Peterson, C.

10.1101/588731 — physiology — Posted on 2019-03-26

610 Functional relevance of dual olfactory bulb in olfactory coding

Kuruppath, P.; Belluscio, L.

10.1101/588996 — neuroscience — Posted on 2019-03-26

611 Characteristic sounds facilitate object search in real-life scenes

Kvasova, D.; Garcia-Vernet, L.; Soto-Faraco, S.

10.1101/563080 — neuroscience — Posted on 2019-03-26

612 Time-resolved NMR monitoring of tRNA maturation

Barraud, P.; Gato, A.; Heiss, M.; Catala, M.; Kellner, S.; Tisne, C.

10.1101/588814 — molecular biology — Posted on 2019-03-26

613 A Membrane-Bound Cytochrome Enables Methanosarcina acetivorans to Conserve Energy to Support Growth from Extracellular Electron Transfer

Holmes, D.; Ueki, T.; Tang, H.-Y.; Zhou, J.; Smith, J.; Chaput, G.; Lovley, D.

10.1101/590380 — microbiology — Posted on 2019-03-26

614 Evolutionary dynamics and diversification in changing environments

Alekseeva, E.; Ispolatov, I.; Doebeli, M.

10.1101/590406 — biophysics — Posted on 2019-03-26

615 DEEPCON: Protein Contact Prediction using Dilated Convolutional Neural Networks with Dropout

Adhikari, B.

10.1101/590455 — bioinformatics — Posted on 2019-03-26

616 Metabolic cost calculations of gait using musculoskeletal energy models, a comparison study

Koelewijn, A. D.; Heinrich, D.; van den Bogert, A. J.

10.1101/588590 — physiology — Posted on 2019-03-26

617 Mechanisms of Economic Decisions under Sequential Offers

Ballesta, S.; Padoa-Schioppa, C.

10.1101/590422 — neuroscience — Posted on 2019-03-26

618 Bioremediation of soils contaminated with petroleum solid wastes and drill cuttings by Pleurotus sp. strains under different treatment scales

Romero-Silva, R.; Sanchez Reyes, A.; Diaz-Rodriguez, Y.; Batista-Garcia, R. A.; Hernandez-Hernandez, D.; Tabullo de Robles, J.

10.1101/588673 — microbiology — Posted on 2019-03-26

619 Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity

Mikhaylova, A. G.; Mikhailova, A. A.; Ushakova, K.; Tretyakov, E.; Iurchenko, A.; Zazhytska, M.; Knorre, D.; Zdobnov, E.; Fleischmann, Z.; Annis, S.; Franco, M.; Wasko, K.; Kunz, W.; Mazunin, I.; Nikolaev, S.; Reymond, A.; Khrapko, K.; Gunbin, K.; Popadin, K.

10.1101/589168 — genomics — Posted on 2019-03-26

620 A Signature of Passivity? An Explorative Study of the N3 Event-Related Potential Component in Passive Oddball Tasks

Kotchoubey, B.; Pavlov, Y. G.

10.1101/271502 — neuroscience — Posted on 2019-03-26

621 Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

Ibn-Salem, J.; Andrade-Navarro, M. A.

10.1101/257584 — genomics — Posted on 2019-03-26

622 Do Arabidopsis Squamosa promoter binding Protein-Like genes act together in plant acclimation to copper or zinc deficiency?

Schulten, A.; Bytomski, L.; Quintana, J.; Bernal, M.; Kraemer, U.

10.1101/590182 — plant biology — Posted on 2019-03-26

623 The C-terminal domains SnRK2-box and ABA-box have a role in sugarcane SnRK2s auto-activation and activity

Righetto, G. L.; Sriranganadane, D.; Halabelian, L.; Gottschald Chiodi, C.; Elkins, J.; Massirer, K. B.; Gileadi, O.; Menossi, M.; Counago, R.

10.1101/589903 — plant biology — Posted on 2019-03-26

624 Practiced naming of objects and actions: An fMRI study

Delikishkina, E.; Lingnau, A.; Miceli, G.

10.1101/590026 — neuroscience — Posted on 2019-03-26

625 Simultaneous tracking of division and differentiation from individual hematopoietic stem and progenitor cells reveals within-family homogeneity despite population heterogeneity

Tak, T.; Prevedelllo, G.; Simon, G.; Paillon, N.; Duffy, K. R.; Perie, L.

10.1101/586354 — immunology — Posted on 2019-03-26

626 Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium

Taylor, G.; Huang, H.-I.; Fee, B. E.; Youssef, N.; Cantillana, V.; Schoenborn, A.; Rogala, A. R.; Buckley, A. F.; Vallance, B. A.; Gulati, A. S.; Hammer, G. E.

10.1101/575415 — immunology — Posted on 2019-03-26

627 Scientific evaluation of negative exome sequencing followed by systematic scoring of candidate genes to decipher the genetics of neurodevelopmental disorders

Buttner, B.; Martin, S.; Finck, A.; Arelin, M.; Baade-Buttner, C.; Bartolomaeus, T.; Bauer, P.; Bertsche, A.; Bernhard, M. K.; Biskup, S.; Di Donato, N.; Elgizouli, M.; Ewald, R.; Heine, C.; Hellenbroich, Y.; Hentschel, J.; Hoffjan, S.; Horn, S.; Hornemann, F.; Huhle, D.; Kamphausen, S. B.; Kiess, W.; Krey, I.; Kuechler, A.; Liesfeld, B.; Merkenschlager, A.; Mitter, D.; Muschke, P.; Pfaffle, R.; Polster, T.; Schanze, I.; Schlump, J.-U.; Syrbe, S.; Wieczorek, D.; Zenker, M.; Lemke, J. R.; Le Duc, D.; Platzer, K.; Abou Jamra, R.

10.1101/588517 — genetics — Posted on 2019-03-26

628 The dot-compartment revealed? Diffusion MRI with ultra-strong gradients and spherical tensor encoding in the living human brain

Tax, C. M. W.; Szczepankiewicz, F.; Nilsson, M.; Jones, D. K.

10.1101/584730 — neuroscience — Posted on 2019-03-26

629 The PIWI/piRNA response is relaxed in a rodent that lacks mobilizing transposable elements

Vandewege, M. W.; Platt, R. N.; Merriman, D. K.; Ray, D. A.; Hoffmann, F. G.

10.1101/587030 — evolutionary biology — Posted on 2019-03-26

630 PamgeneAnalyzeR open and reproducible pipeline for kinase profiling

Bekkar, A.; Nasrallah, A.; Guex, N.; Fajas, L.; Xenarios, I.; Lopez-Mejia, I. C.

10.1101/589838 — bioinformatics — Posted on 2019-03-26

631 Integrative analysis of epigenetics data identifies gene-specific regulatory elements

Schmidt, F.; Marx, A.; Hebel, M.; Wegner, M.; Baumgarten, N.; Kaulich, M.; Goeke, J.; Vreeken, J.; Schulz, M. H. H.

10.1101/585125 — bioinformatics — Posted on 2019-03-26

632 Target of selective auditory attention can be robustly followed with MEG

Kurmanaviciute, D.; Rantala, A.; Jas, M.; Valila, A.; Parkkonen, L.

10.1101/588491 — neuroscience — Posted on 2019-03-26

633 Near-optimal combination of disparity across a log-polar scaled visual field

Maiello, G.; Chessa, M.; Bex, P. J.; Solari, F.

10.1101/589937 — neuroscience — Posted on 2019-03-26

634 Xrn1 activity broadly represses RNA polymerase II occupancy at mammalian but not viral promoters during herpesvirus infection

Hartenian, E.; Glaunsinger, B.

10.1101/585984 — microbiology — Posted on 2019-03-26

635 The TCR/peptide/MHC complex with a superagonist peptide shows similar interface and reduced flexibility compared to the complex with a self-peptide

Salutari, I.; Martin, R.; Caflisch, A.

10.1101/588483 — immunology — Posted on 2019-03-26

636 Distribution of iridescent colours in hummingbird communities results from the interplay between selection for camouflage and communication

Gruson, H.; Elias, M.; Parra, J. L.; Andraud, C.; Berthier, S.; Doutrelant, C.; Gomez, D.

10.1101/586362 — ecology — Posted on 2019-03-26

637 Graph analysis of looming-selective networks in the tectum, and its replication in a simple computational model

Khakhalin, A.

10.1101/589887 — neuroscience — Posted on 2019-03-26

638 Balanced activity of multiple FtsW and RodA proteins is crucial for maintaining cell shape and antibiotic resistance in Listeria monocytogenes

Rismondo, J.; Halbedel, S.; Grundling, A.

10.1101/589911 — microbiology — Posted on 2019-03-26

639 Hybrid decay: a transgenerational epigenetic decline in vigor and viability triggered in backcross populations of teosinte with maize

Xue, W.; Anderson, S. N.; Wang, X.; Yang, L.; Crisp, P. A.; Li, Q.; Noshay, J.; Albert, P. S.; Birchler, J. A.; Bilinski, P.; Stitzer, M.; Ross-Ibarra, J.; Flint-Garcia, S.; Chen, X.; Springer, N. M.; Doebley, J. F.

10.1101/588715 — genetics — Posted on 2019-03-26

640 Stoichiometric constraints modulate the effects of temperature and nutrients on biomass distribution and community stability

Sentis, A.; Haegeman, B.; Montoya, J. M.

10.1101/589895 — ecology — Posted on 2019-03-26

641 Estimation of mutual information for real-valued data with error bars and controlled bias

Holmes, C. M.; Nemenman, I.

10.1101/589929 — bioinformatics — Posted on 2019-03-26

642 Two forms of phosphomannomutase in gammaproteobacteria: The overlooked membrane-bound form of AlgC is required for twitching motility of Lysobacter enzymogenes

Qian, G.; Fei, S.; Galperin, M. Y.

10.1101/589796 — microbiology — Posted on 2019-03-26

643 Combinatorial genetic analysis of a regulatory network reveals the importance of higher order epistasis for gene deletion phenotypes

new, a.; Lehner, B.

10.1101/589606 — genetics — Posted on 2019-03-26

644 Mutualistic interactions with phoretic mites Poecilochirus carabi expand the realised thermal niche of the burying beetle Nicrophorus vespilloides

Sun, S.-J.; Kilner, R. M.

10.1101/590125 — ecology — Posted on 2019-03-26

645 The FH2 domain of formin proteins is critical for platelet cytoskeletal dynamics

Green, H. L. H.; Zuidscherwoude, M.; Thomas, S. G.

10.1101/589861 — cell biology — Posted on 2019-03-26

646 Breast cancer classification based on proteotypes obtained by SWATH mass spectrometry

Bouchal, P.; Schubert, O. T.; Faktor, J.; Capkova, L.; Imrichova, H.; Zoufalova, K.; Paralova, V.; Hrstka, R.; Liu, Y.; Ebhardt, H. A.; Budinska, E.; Nenutil, R.; Aebersold, R.

10.1101/583443 — cancer biology — Posted on 2019-03-26

647 ntEdit: scalable genome sequence polishing

Warren, R. L.; Coombe, L.; Mohamadi, H.; Zhang, J.; Jaquish, B.; Isabel, N.; Jones, S. J.; Bousquet, J.; Bohlmann, J.; Birol, I.

10.1101/565374 — bioinformatics — Posted on 2019-03-26

648 Low-background Acyl-biotinyl Exchange Largely Eliminates the Co-isolation of Non-S-acylated Proteins and Enables Deep S-acylproteomic Analysis

Zhou, B.; Wang, Y.; Yan, Y.; Mariscal, J.; Di Vizio, D.; Freeman, M. R.; Yang, W.

10.1101/588988 — biochemistry — Posted on 2019-03-26

649 Crab fisherman communities in north Brazil: a new high risk population for vampire bat rabies

de Paula Silva, N.; Andrade, E. A.; Cardoso, D.; de Souza Guimaraes, R.; Silva, M. B.; Gomes Nascimento, K. K.; de Arruda Xavier, D.; Abel Bezerra, I.

10.1101/590083 — epidemiology — Posted on 2019-03-26

650 Levels of histidine-rich glycoprotein variants in human blood are associated to chronological age and predict mortality

Hong, M.-G.; Dodig-Crnkovic, T.; Chen, X.; Drobin, K.; LEE, W.; Wang, Y.; Sjöberg, R.; Odeberg, J.; Hamsten, A.; Silveira, A.; Hall, P.; Nilsson, P.; Pawitan, Y.; Hägg, S.; Uhlen, M.; Pedersen, N. L.; Magnusson, P. K. E.; Schwenk, J. M.

10.1101/464909 — epidemiology — Posted on 2019-03-26

651 Poor seed quality, reduced germination, and decreased seedling vigor in soybean is linked to exposure of the maternal lines to drought stress

wijewardana, C.; Reddy, K. R.; Krutz, L.; Gao, W.; Bellaloui, N.

10.1101/590059 — plant biology — Posted on 2019-03-26

652 A Simple way to Improve a Conventional A/O-MBR for High Simultaneous Carbon and Nutrients Removal from Synthetic Municipal Wastewater

Adoonsook, D.; Chia-Yuan, C.; Wongrueng, A.; Pumas, C.

10.1101/590042 — microbiology — Posted on 2019-03-26

653 Computational prediction and analysis of very high risk single nucleotide polymorphisms in human cytochrome P450 oxidoreductase gene

Dhas, B. B.; K, R.; S, S.; Pavuluri, P.; K, Y. R.

10.1101/590067 — genomics — Posted on 2019-03-26

654 Genetic Mapping Of Morpho-Physiological Traits Involved During Reproductive Stage Drought Tolerance In Rice

Barik, S. R.; Pandit, E.; Mohanty, S. P.; pradhan, s. K.; Mohapatra, T.

10.1101/590075 — genetics — Posted on 2019-03-26

655 Infection of Plasmodiophora brassicae changes the fungal endophyte community of tumourous stem mustard roots as revealed by high-throughput sequencing and culture-dependent methods

Tian, X.; Wang, D.; Mao, Z.; Pan, L.; Liao, J.; Cai, Z.

10.1101/590018 — microbiology — Posted on 2019-03-26

656 Sex allocation conflict and sexual selection throughout the lifespan of eusocial colonies

Avila, P.; Fromhage, L.; Lehmann, L.

10.1101/454512 — evolutionary biology — Posted on 2019-03-26

657 Biophysical modeling of VIM to assess contributions of oscillatory activity to essential tremor

Lee, S.; Segar, D. J.; Asaad, W.; Jones, S.

10.1101/339846 — neuroscience — Posted on 2019-03-26

658 Efficient and specific oligo-based depletion of rRNA

Kraus, A. J.; Brink, B. G.; Siegel, T. N.

10.1101/589622 — molecular biology — Posted on 2019-03-26

659 Ethanolamine regulates CqsR quorum-sensing signaling in Vibrio cholerae

Ng, W.-L.; Watve, S.; Barrasso, K.; Jung, S. A.; Davis, K. J.; Hawver, L. A.; Khataokar, A.; Palaganas, R. G.; Neiditch, M. B.; Perez, L. J.

10.1101/589390 — microbiology — Posted on 2019-03-26

660 A major role for Eco1 in regulating cohesin-mediated mitotic chromosome folding

Dauban, L.; Montagne, R.; Thierry, A.; Lazar-Stefanita, L.; Gadal, O.; Cournac, A.; Koszul, R.; Beckouet, F.

10.1101/589101 — genetics — Posted on 2019-03-26

661 Gene-level quantitative trait mapping in an expanded C. elegans multiparent experimental evolution panel

Noble, L. M.; Rockman, M. V.; Teotonio, H.

10.1101/589432 — evolutionary biology — Posted on 2019-03-26

662 Drosophila ovarian germline stem cell cytocensor projections dynamically receive and attenuate BMP signalling

Wilcockson, S. G.; Ashe, H. L.

10.1101/370486 — developmental biology — Posted on 2019-03-26

663 An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21

McRae, E. K. S.; Dupas, S. J.; Booy, E. P.; Piragasam, R. S.; Fahlman, R. P.; McKenna, S. A.

10.1101/588798 — biochemistry — Posted on 2019-03-26

664 Genome-wide analysis of MIKC-type MADS-box genes in wheat: pervasive duplications may have facilitated adaptation to different environmental conditions

Schilling, S.; Kennedy, A.; Pan, S.; Jermiin, L. S.; Melzer, R.

10.1101/585232 — plant biology — Posted on 2019-03-26

665 Evaluating Muscle Fiber Contractility and the Transcriptome, Proteome, Metabolome, and Lipidome of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy

Van Pelt, D. W.; Kharaz, Y. A.; Sarver, D. C.; Eckhardt, L. R.; Dzierzawski, J. T.; Disser, N. P.; Piacentini, A. N.; Comerford, E.; McDonagh, B.; Mendias, C. L.

10.1101/589424 — physiology — Posted on 2019-03-26

666 HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

Strutzenberg, T. S.; Garcia-Ordonez, R.; Novick, S.; Park, H.; Chang, M. R.; Doebellin, C.; He, Y.; Patouret, R.; Kamenecka, T.; Griffin, P. R.

10.1101/588830 — biophysics — Posted on 2019-03-26

667 Rapid and dynamic nucleic acid hybridization enables enzymatic oligonucleotide synthesis by cyclic reversible termination

Hoff, K.; Halpain, M.; Garbagnati, G.; Edwards, J.; Zhou, W.

10.1101/561092 — synthetic biology — Posted on 2019-03-26

668 Chloroplasts Require Glutathione Reductase to Balance Reactive Oxygen Species and Maintain Efficient Photosynthesis

Müller-Schüssele, S. J.; Wang, R.; Gütle, D. D.; Romer, J.; Rodriguez-Franco, M.; Scholz, M.; Lüth, V. M.; Kopriva, S.; Dörmann, P.; Schwarzländer, M.; Reski, R.; Michael, H.; Meyer, A. J.

10.1101/588442 — plant biology — Posted on 2019-03-26

669 Phase separation of zonula occludens proteins drives formation of tight junctions

Beutel, O.; Maraspini, R.; Pombo-Garcia, K.; Martin-Lemaitre, C.; Honigmann, A.

10.1101/589580 — cell biology — Posted on 2019-03-26

670 Epigenomic Landscape of Arabidopsis thaliana Metabolism Reveals Bivalent Chromatin on Specialized Metabolic Genes

Zhao, K.; Rhee, S. Y.

10.1101/589036 — systems biology — Posted on 2019-03-26

671 Unified rational protein engineering with sequence-only deep representation learning

Alley, E. C.; Khimulya, G.; Biswas, S.; AlQuraishi, M.; Church, G. M.

10.1101/589333 — synthetic biology — Posted on 2019-03-26

672 Cross-talk between m6A and m1A regulators, YTHDF2 and ALKBH3 fine-tunes mRNA expression

Lao, N.; Barron, N.

10.1101/589747 — molecular biology — Posted on 2019-03-26

673 A Polybasic Domain in aPKC Mediates Par-6-Dependent Control of Plasma Membrane Targeting and Kinase Activity

Hong, Y.; Dong, W.; Lu, J.; Zhang, X.; Wu, Y.; Lettieri, K.; Hammond, G.

10.1101/588624 — cell biology — Posted on 2019-03-26

674 Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2 (PC2)

Wang, Q.; Hedger, G.; Aryal, P.; Grieben, M.; Nasrallah, C.; Baronina, A.; Pike, A.; Shi, J.; Carpenter, E. P.; Sansom, M.

10.1101/589515 — biophysics — Posted on 2019-03-26

675 Metabolic labeling of RNAs uncovers hidden features and dynamics of the Arabidopsis thaliana transcriptome

Szabo, E. X.; Reichert, P.; Lehniger, M.-K.; Ohmer, M.; de Francisco Amorim, M.; Gowik, U.; Schmitz-Linneweber, C.; Laubinger, S.

10.1101/588780 — plant biology — Posted on 2019-03-26

676 Size- and stage-dependence in cause-specific mortality of migratory brown trout

Nater, C. R.; Vindenes, Y.; Aass, P.; Cole, D.; Langangen, O.; Moe, J.; Rustadbakken, A.; Turek, D.; Vollestad, L. A.; Ergon, T.

10.1101/544742 — ecology — Posted on 2019-03-26

677 Shh induces symmetry breaking in the presomitic mesoderm by inducing tissue shear and orientated cell rearrangements

Yin, J.; Saunders, T. E.

10.1101/589549 — developmental biology — Posted on 2019-03-26

678 Random birth order and bursty Notch ligand expression drive the stochastic AC/VU cell fate decision in C. elegans

Gritti, N.; Kienle, S.; Kroll, J. R.; Kriselj, A.; Goos, Y.; van Zon, J.

10.1101/588418 — developmental biology — Posted on 2019-03-26

679 The Human Exonuclease-1 Interactome And Phosphorylation Sites

Eid, W.; Hess, D.; Koenig, C.; Gentili, C.; Ferrari, S.

10.1101/588574 — cell biology — Posted on 2019-03-26

680 Aurora kinase A mediated phosphorylation of mPOU is critical for skeletal muscle differentiation

Karthigeyan, D.; Bose, A.; Boopathi, R.; Rao, V. J.; Shima, H.; Bharathy, N.; Igarashi, K.; Taneja, R.; Kundu, T. K.

10.1101/589754 — cell biology — Posted on 2019-03-26

681 Development of behavioral modernity by hominins around 70,000 years ago was associated with simultaneous acquisition of a novel component of imagination, called prefrontal synthesis, and conversion of a preexisting rich-vocabulary non-recursive communication system to a fully recursive syntactic language

Vyshedskiy, A.

10.1101/166520 — evolutionary biology — Posted on 2019-03-26

682 Hemimetabolous insects elucidate the origin of sexual development via alternative splicing

Wexler, J.; Delaney, E.; Belles, X.; Schal, C.; Wada-Katsumata, A.; Amicucci, M.; Kopp, A.

10.1101/587964 — developmental biology — Posted on 2019-03-26

683 Both galactosaminogalactan and α-1,3-glucan contribute to aggregation of Aspergillusoryzae hyphae in liquid culture

Miyazawa, K.; Yoshimi, A.; Sano, M.; Tabata, F.; Sugahara, A.; Kasahara, S.; Koizumi, A.; Yano, S.; Nakajima, T.; Abe, K.

10.1101/589408 — cell biology — Posted on 2019-03-26

684 Disharmony of the world’s island floras

Koenig, C.; Weigelt, P.; Taylor, A.; Stein, A.; Dawson, W.; Essl, F.; Pergl, J.; Pysek, P.; van Kleunen, M.; Winter, M.; Chatelain, C.; Wieringa, J. J.; Krestov, P.; Kreft, H.

10.1101/523464 — ecology — Posted on 2019-03-26

685 DDX3 depletion selectively represses translation of structured mRNAs

Calviello, L.; Venkataramanan, S.; Rogowski, K. J.; Wyler, E.; Tejura, M.; Thai, B.; Krol, J.; Filipowicz, W.; Landthaler, M.; Floor, S. N.

10.1101/589218 — molecular biology — Posted on 2019-03-26

686 Comparative ChIP-seq (Comp-ChIP-seq): a novel computational methodology for genome-wide analysis

Blanco, E.; Di Croce, L.; Aranda, S.

10.1101/532622 — genomics — Posted on 2019-03-26

687 In vitro reconstitution of kinetochore-microtubule interface reveals a fundamental error correction mechanism

Doodhi, H.; Kasciukovic, T.; Gierlinski, M.; Li, S.; Clayton, L.; Tanaka, T. U.

10.1101/455873 — cell biology — Posted on 2019-03-26

688 Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid in vivo functional genomics

Hulton, C. H.; Costa, E. A.; Shah, N. S.; Quintanal-Villalonga, A.; Heller, G.; de Stanchina, E.; Rudin, C. M.; Poirier, J. T.

10.1101/588921 — cancer biology — Posted on 2019-03-26

689 Data from an electronic health informatics pipeline to describe clearance dynamics of Hepatitis B surface antigen (HBsAg) and e-Antigen (HBeAg) in chronic HBV infection

Downs, L. O.; Smith, D.; Lumley, S. F.; Patel, M.; McNaughton, A. L.; Mokaya, J.; Ansari, A.; Salih, H.; Varnai, K. A.; Freeman, O.; Cripps, S.; Phillips, J.; Collier, J.; Woods, K.; Channon, K.; Davies, J.; Barnes, E.; Jeffery, K.; Matthews, P. C.

10.1101/494500 — microbiology — Posted on 2019-03-26

690 VHL Synthetic Lethality Signatures Uncovered by Genotype-specific CRISPR-Cas9 Screens

Sun, N.; Petiwala, S.; Lu, C.; Hutti, J. E.; Hu, M.; Hu, M.; Domanus, M. H.; Mitra, D.; Addo, S. N.; Miller, C. P.; Chung, N.

10.1101/588707 — cancer biology — Posted on 2019-03-26

691 Development of a drug repressible β-catenin mutant mouse to examine effect of activated β-catenin signaling on long-term maintenance of mammary tumor growth

Gorman, J. L.; Adams, J. R.; Jones, E. M.; Egan, S. E.; Woodgett, J. R.

10.1101/588459 — cancer biology — Posted on 2019-03-26

692 No evidence that inbreeding avoidance is up-regulated during the ovulatory phase of the menstrual cycle

Holzleitner, I. J.; Driebe, J. C.; Arslan, R. C.; Hahn, A. C.; Lee, A. J.; O'Shea, K. J.; Gerlach, T. M.; Penke, L.; Jones, B. C.; DeBruine, L. M.

10.1101/192054 — animal behavior and cognition — Posted on 2019-03-26

693 Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization

Lamelza, P.; Young, J. M.; Noble, L. M.; Isakharov, A.; Palanisamy, M.; Rockman, M. V.; Malik, H. S.; Ailion, M.

10.1101/588152 — evolutionary biology — Posted on 2019-03-26

694 Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments.

Hafner, A.-S.; Donlin-Asp, P.; Leitch, B.; Herzog, E.; Schuman, E. M.

10.1101/363184 — neuroscience — Posted on 2019-03-26

695 variant2literature: full text literature search for genetic variants

Lin, Y.-H.; Lu, Y.-C.; Hsu, J. S.; Lee, K.-H.; Cheng, Y.-W.; Chen, Y.-C.; Chen, T.-F.; Fan, J.-S.; Tu, C.-T.; Hsu, C.-M.; Chou, C.-C.; Chen, P.-L.; Tu, Y.-C. E.; Chen, C.-Y.

10.1101/583450 — genetics — Posted on 2019-03-26

696 Disharmony of the world’s island floras

Koenig, C.; Weigelt, P.; Taylor, A.; Stein, A.; Dawson, W.; Essl, F.; Pergl, J.; Pysek, P.; van Kleunen, M.; Winter, M.; Chatelain, C.; Wieringa, J. J.; Krestov, P.; Kreft, H.

10.1101/523464 — ecology — Posted on 2019-03-26

697 Adverse effects of Bacillus thuringiensis bioinsecticide on non-target Drosophila species

Babin, A.; Nawrot-Esposito, M.-P.; Gallet, A.; Gatti, J.-L.; Poirie, M.

10.1101/541847 — ecology — Posted on 2019-03-26

698 Exploring the archaeome: detection of archaeal signatures in the human body

Pausan, M. R.; Csorba, C.; Singer, G.; Till, H.; Schoepf, V.; Santigli, E.; Klug, B.; Hoegenauer, C.; Blohs, M.; Moissl-Eichinger, C.

10.1101/334748 — microbiology — Posted on 2019-03-26

699 Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence

McCulloch, L.; Allan, S. M.; Smith, C. J.; McColl, B. W.

10.1101/587881 — immunology — Posted on 2019-03-26

700 ER-Ca2+ sensor STIM regulates neuropeptides required for development under nutrient restriction in Drosophila

M, M.; Wegener, C.; Hasan, G.

10.1101/386649 — developmental biology — Posted on 2019-03-26

701 Comparative genomics guides elucidation of vitamin B12 biosynthesis in novel human associated Akkermansia

Kirmiz, N.; Galindo, K.; Cross, K. L.; Luna, E.; Rhoades, N.; Podar, M.; Flores, G. E.

10.1101/587527 — genomics — Posted on 2019-03-26

702 Prediction of inter-residue contacts with DeepMetaPSICOV in CASP13

Kandathil, S. M.; Greener, J. G.; Jones, D. T.

10.1101/586800 — bioinformatics — Posted on 2019-03-26

703 Single particle diffusion characterization by deep learning

Granik, N.; Weiss, L. E.; Levine, M.; Chein, M.; Perlson, E.; Roichman, Y.; Shechtman, Y.

10.1101/588533 — biophysics — Posted on 2019-03-26

704 Proteinarium: Multi-Sample Protein-Protein Interaction Visualization and Analysis Tool

Armanious, D.; Schuster, J.; Istrail, S.; Padbury, J.; Uzun, A.

10.1101/589085 — bioinformatics — Posted on 2019-03-26

705 Have It, Know It, but Do Not Show It: Examining Physiological Arousal, Anxiety, and Facial Expressions over the Course of a Social Skills Intervention for Autistic Adolescents

Jain, N.; Ahamed, S. I.; Bozdag, S.; Dolan, B. K.; McVey, A. J.; Willar, K. S.; Pleiss, S. S.; Murphy, C. C.; Casnar, C. L.; Potts, S.; Cibich, D.; Nelsen-Freund, K.; Fernandez, D.; Hernandez, I.; Van Hecke, A. V.

10.1101/582676 — bioinformatics — Posted on 2019-03-25

706 The distribution of fitness effects among synonymous mutations in a gene under selection

Lebeuf-Taylor, E.; McCloskey, N.; Hinz, A.; Bailey, S.; Kassen, R.

10.1101/553610 — evolutionary biology — Posted on 2019-03-25

707 Corticolimbic circuit structure moderates an association between early life stress and later trait anxiety

Kim, M. J.; Farber, M. J.; Knodt, A. R.; Hariri, A. R.

10.1101/581926 — neuroscience — Posted on 2019-03-25

708 Scedar: a scalable Python package for single-cell RNA-seq exploratory data analysis

Zhang, Y.; Taylor, D. M.

10.1101/375196 — bioinformatics — Posted on 2019-03-25

709 Untapped viral diversity in global soil metagenomes

Graham, E. B.; Paez-Espino, D.; Brislawn, C.; Neches, R. Y.; Hofmockel, K. S.; Wu, R.; Kyrpides, N. C.; Jansson, J. K.; McDermott, J. E.

10.1101/583997 — microbiology — Posted on 2019-03-25

710 Transcranial ultrasound selectively biases decision-making in primates

Kubanek, J.; Brown, J.; Ye, P.; Pauly, K. B.; Moore, T.; Newsome, W.

10.1101/486134 — neuroscience — Posted on 2019-03-25

711 Emotionotopy: Gradients encode emotion dimensions in right temporo-parietal territories

Lettieri, G.; Handjaras, G.; Ricciardi, E.; Leo, A.; Papale, P.; Betta, M.; Pietrini, P.; Cecchetti, L.

10.1101/463166 — neuroscience — Posted on 2019-03-25

712 Co-localization of pain and reduced intra-epidermal nerve fibre density in individuals with HIV-associated sensory neuropathy

Patel, I. G.; Kamerman, P. R.

10.1101/587345 — neuroscience — Posted on 2019-03-25

713 NanoR: a user-friendly R package to analyze and compare nanopore sequencing data

Bolognini, D.; Bartalucci, N.; Mingrino, A.; Vannucchi, A. M.; Magi, A.

10.1101/514232 — bioinformatics — Posted on 2019-03-25

714 System analysis of cross-talk between nuclear receptors reveals an opposite regulation of the cell cycle by LXR and FXR in human HepaRG liver cells

Wigger, L.; Casals Casas, C.; Baruchet, M.; Trang, K. B.; Pradervand, S.; Naldi, A.; Desvergne, B.

10.1101/514976 — physiology — Posted on 2019-03-25

715 Motivation and Cognitive Control in Depression

Grahek, I.; Shenhav, A.; Musslick, S.; Krebs, R. M.; Koster, E. H. W.

10.1101/500561 — neuroscience — Posted on 2019-03-25

716 Impact of temperature and photoperiod on survival and biomarkers of senescence in common woodlouse

DEPEUX, C.; SAMBA-LOUAKA, A.; BRAQUART-VARNIER, C.; MOREAU, J.; LEMAITRE, J.-F.; LAVERRE, T.; PAULHAC, H.; DECHAUME-MONCHARMONT, F.-X.; GAILLARD, J.-M.; BELTRAN-BECH, S.

10.1101/433011 — evolutionary biology — Posted on 2019-03-25

717 Metacommunity-scale biodiversity regulation and the self-organized emergence of macroecological patterns

Dinner O'Sullivan, J. L.; Knell, R. J.; Rossberg, A. G.

10.1101/489336 — ecology — Posted on 2019-03-25

718 Anchoring of actin to the plasma membrane enables tension production in the fission yeast cytokinetic ring

Wang, S.; O'Shaughnessy, B.

10.1101/586792 — cell biology — Posted on 2019-03-25

719 Cellular and network mechanisms may generate sparse coding of sequential object encounters in hippocampal-like circuits

Trinh, A.-T.; Clarke, S. E.; Harvey-Girard, E.; Maler, L.

10.1101/571414 — neuroscience — Posted on 2019-03-25

720 Regulation of hippocampal memory by mTORC1 in somatostatin interneuron

Artinian, J.; Jordan, A.; Khlaifia, A.; Honore, E.; La Fontaine, A.; Racine, A.-S.; Laplante, I.; Lacaille, J.-C.

10.1101/580670 — neuroscience — Posted on 2019-03-25

721 Metapopulation connectedness and the evolution of multiple life-history traits

Masier, S.; Bonte, D.

10.1101/476093 — ecology — Posted on 2019-03-25

722 Nitrogen addition pulse has minimal effect in Wyoming big sagebrush (Artemisia tridentata) communities on the Pinedale Anticline, Wyoming (USA)

Beltz, C. W.; Mobley, M. L.; Burke, I. C.

10.1101/446294 — ecology — Posted on 2019-03-25

723 Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 30-day timeline with Dexamethasone exposure.

Robinson, J.; Turkington, S.; Abey, S.; Kenea, N.; Henderson, W.

10.1101/355552 — cell biology — Posted on 2019-03-25

724 Membrane bending energy and tension govern mitochondrial division

Mahecic, D.; Carlini, L.; Kleele, T.; Colom, A.; Goujon, A.; Matile, S.; Roux, A.; Manley, S.

10.1101/255356 — biophysics — Posted on 2019-03-25

725 Direct visualization of native CRISPR target search in live bacteria reveals Cascade DNA surveillance mechanism

Vink, J.; Martens, K.; Vlot, M.; McKenzie, R.; Almendros, C.; Estrada Bonilla, B.; Brocken, D.; Hohlbein, J.; Brouns, S.

10.1101/589119 — microbiology — Posted on 2019-03-25

726 Genomic and phylogenetic analysis of Salmonella Typhimurium and its monophasic variants responsible for invasive endemic infections in Colombia

Li, Y.; Pulford, C. V.; Diaz, P.; Perez-Sepulveda, B. M.; Duarte, C.; Predeus, A. V.; Wiesner, M.; Heavens, D.; Low, R.; Schudoma, C.; Lipscombe, J.; Montano, A.; Hall, N.; Moreno, J.; Hinton, J. C. D.

10.1101/588608 — genomics — Posted on 2019-03-25

727 Magnus Representation of Genome Sequences

Wu, C.; Ren, S.; Wu, J.; Xia, K.

10.1101/588582 — genomics — Posted on 2019-03-25

728 The role of genetic constraints and social environment in explaining female extra-pair mating

Wang, D.; Forstmeier, W.; Martin, K.; Wilson, A.; Kempenaers, B.

10.1101/588475 — evolutionary biology — Posted on 2019-03-25

729 Data Resource Profile:The Dementias Platform UK (DPUK) Data Portal

Bauermeister, S.; Orton, C.; Thompson, S.; Barker, R.; Bauermeister, J.; Ben-Shlomo, Y.; Brayne, C.; Burn, D.; Campbell, A.; Calvin, C.; Chandran, S.; Chaturvedi, N.; Chene, G.; Chessell, I.; Corbett, A.; Davis, D.; Denis, M.; DuFouil, C.; Elliott, P.; Fox, N.; Hill, D.; Hofer, S.; Hu, M.; Jindra, C.; Kee, F.; Kim, C.-H.; Kim, C.; Kivimaki, M.; Koychev, I.; Kwan, J.; Lawson, R.; Leroi, I.; Linden, G.; Love, S.; Lovestone, S.; Lyons, R.; MacKay, C.; Matthews, P.; McGuiness, B.; Middleton, L.; Moody, C.; Moore, K.; Na, D. L.; O'Brien, J.; Ourselin, S.; Paranjothy, S.; Park, K. S.; Porteous, D.;

10.1101/582155 — neuroscience — Posted on 2019-03-25

730 Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC

10.1101/586396 — cancer biology — Posted on 2019-03-25

731 The McGill Face Database: validation and insights into the recognition of facial expressions of complex mental states

Schmidtmann, G.; Jennings, B. J.; Sandra, D. A.; Pollock, J.; Gold, I.

10.1101/586453 — animal behavior and cognition — Posted on 2019-03-25

732 Direction of gait asymmetry following stroke determines acute response to locomotor task

Little, V. L.; Perry, L. A.; Mercado, M. W.; Kautz, S. A.; Patten, C.

10.1101/588103 — neuroscience — Posted on 2019-03-25

733 SVCurator: A Crowdsourcing app to visualize evidence of structural variants for the human genome

Chapman, L. M.; Spies, N.; Pai, P.; Lim, C. S.; Carroll, A.; Narzisi, G.; Watson, C. M.; Proukakis, C.; Clarke, W. E.; Nariai, N.; Dawson, E.; Jones, G.; Blankenberg, D.; Brueffer, C.; Xiao, C.; Kolora, S. R. R.; Alexander, N.; Wolujewicz, P.; Ahmed, A.; Smith, G.; Shehreen, S.; Wenger, A. M.; Salit, M.; Zook, J. M.

10.1101/581264 — genomics — Posted on 2019-03-25

734 Beyond early development: observing zebrafish over 6 weeks with hybrid optical and optoacoustic imaging

Vetschera, P.; Koberstein-Schwarz, B.; Schmitt-Manderbach, T.; Dietrich, C.; Hellmich, W.; Chekkoury, A.; Symvoulidis, P.; Reber, J.; Westmeyer, G.; Lopez-Schier, H.; Omar, M.; Ntziachristos, V.

10.1101/586933 — biophysics — Posted on 2019-03-25

735 Structural and mutational analysis of the ribosome-arresting human XBP1u

Shanmuganathan, V.; Schiller, N.; Magoulopoulou, A.; Cheng, J.; Braunger, K.; Cymer, F.; Berninghausen, O.; Beatrix, B.; Kohno, K.; Heijne, G. v.; Beckmann, R.

10.1101/588681 — biochemistry — Posted on 2019-03-25

736 Cytosolic termini of the FurE transporter regulate endocytosis, pH-dependent gating and specificity

Papadaki, G. F.; Lamprinidis, G.; Zamanos, A.; Mikros, E.; Diallinas, G.

10.1101/588368 — molecular biology — Posted on 2019-03-25

737 The CNS in the face of ART contains T cell origin HIV which can lead to drug resistance

Lustig, G.; Cele, S.; Karim, F.; Ganga, Y.; Khan, K.; Gosnell, B.; Moosa, Y.; Harrichandparsad, R.; Marais, S.; Gupta, R.; Derache, A.; Giandhari, J.; de Oliveira, T.; Govender, K.; Adamson, J.; Patel, V.; Sigal, A.

10.1101/588426 — microbiology — Posted on 2019-03-25

738 Application of Volumetric Absorptive Micro Sampling to Measure Multidimensional Anti-Influenza Hemagglutinin IgG Antibodies by mPlex-Flu Assay

Wang, J.; Li, D.; Wiltse, A.; Emo, J.; Hilchey, S. P.; Zand, M. S.

10.1101/588038 — immunology — Posted on 2019-03-25

739 Acute inflammation is a predisposing factor for weight gain and insulinresistance

Oliveira, E. M.; Silva, J. C.; Ascar, T. P.; Sandri, S.; Marchi, A.; Migliorini, S.; Nakaya, H. T. I.; Fock, R.; Campa, A.

10.1101/583773 — cell biology — Posted on 2019-03-25

740 Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota

Valentini, T. D.; Lucas, S. K.; Binder, K. A.; Cameron, L. C.; Motl, J. A.; Dunitz, J. M.; Hunter, R. C.

10.1101/588640 — microbiology — Posted on 2019-03-25

741 Polyphosphate initiates tau aggregation through intra- and intermolecular scaffolding

Wickramasinghe, S. P.; Lempart, J.; Merens, H. E.; Murphy, J.; Jakob, U.; Rhoades, E.

10.1101/588509 — biophysics — Posted on 2019-03-25

742 Recovery of trait heritability from whole genome sequence data

Wainschtein, P.; Jain, D. P.; Yengo, L.; Zheng, Z.; TOPMed Anthropometry Working Group, ; Trans-Omics for Precision Medicine Consortium, ; Cupples, L. A.; Shadyab, A. H.; McKnight, B.; Shoemaker, B. M.; Mitchell, B. D.; Psaty, B. M.; Kooperberg, C.; Roden, D.; Darbar, D.; Arnett, D. K.; Regan, E. A.; Boerwinkle, E.; Rotter, J. I.; Allison, M. A.; McDonald, M.-L. N.; Chung, M. K.; Smith, N. L.; Ellinor, P. T.; Vasan, R. S.; Mathias, R. A.; Rich, S. S.; Heckbert, S. R.; Redline, S.; Guo, X.; Chen, Y.-D. I.; Liu, C.-T.; Andrade, M. d.; Yanek, L. R.; Albert, C. M.; Hernandez, R. D.; McGarvey, S.

10.1101/588020 — genetics — Posted on 2019-03-25

743 HIV-MALARIA CO-INFECTION AND ITS DETERMINANTS AMONG PATIENTS ATTENDING ANTIRETROVIRAL TREATMENT CLINIC IN ZARIA, NORTH-WESTERN NIGERIA

Gumel, S. D.; Ibrahim, A.; Olayinka, A.; Ibrahim, M. S.; Balogun, M. S.; Usman, A. D.; Ajayi, I.; Ajumobi, O.; Ahmadu, I.; Song, A.; Maifada, A. I.; Abdullahi, H.

10.1101/588855 — epidemiology — Posted on 2019-03-25

744 An high dose of a conjugated linoleic acid increases fatty liver and insulin resistance in lactating mice

HAN, l.; Pang, K.

10.1101/588962 — physiology — Posted on 2019-03-25

745 Prevalence of chronic chikungunya and associated risks factors in the French West Indies (La Martinique). A prospective cohort study

Antoine, B.; Thioune, M.; Abel, S.; Belrosse, G.; Calmont, I.; Cesaire, R.; Cervantes, M.; Fagour, L.; Javelle, E.; Lebris, C.; Najioullah, F.; Pierre-Francois, S.; Roze, B.; Vigan, M.; Laouenan, C.; Cabie, A.; Bally J, Brouste Y, Brunier L, Godaert-Simon L, Ho,

10.1101/588970 — microbiology — Posted on 2019-03-25

746 Taxonomic and functional anuran beta diversity of the subtropical metacommunity respond differentially to environmental and spatial predictors

Dalmolin, D. A.; Ramos Pereira, M. J. V. d. C.; Tozetti, A. M.

10.1101/588947 — ecology — Posted on 2019-03-25

747 Nilotinib, an approved leukemia drug, inhibits Smoothened signaling in Hedgehog-dependent medulloblastoma

Chahal, K. K.; Li, J.; Kufareva, I.; Parle, M.; Durden, D. D.; Wechsler-Reya, R.; Chen, C. C.; Abagyan, R.

10.1101/588897 — cancer biology — Posted on 2019-03-25

748 MgO nanoparticles coated with Polyethylene Glycol as carrier for 2-Methoxyestradiol anticancer drug.

Alfaro, A.; Leon, A.; Guajardo, E.; Reuquen, P.; Torres, F.; Mery, M.; Segura, R.; Zapata, P.; orihuela, p.

10.1101/588939 — cancer biology — Posted on 2019-03-25

749 Study on the Health Communication Behavior of Chinese Doctors on Network Media----Based on the Empirical Investigation of 119 Chinese Doctors

Hu, F.; Wang, P.

10.1101/588863 — scientific communication and education — Posted on 2019-03-25

750 De novo transcriptome assembly of the African bullfrog Pyxicephalus adspersus for molecular analysis of aestivation

Yoshida, N.; Kaito, C.

10.1101/588889 — molecular biology — Posted on 2019-03-25

751 Extensive adaptive immune response of AAVs and Cas proteins in non-human primates

Chen, Y.; Xiao, P.; Bai, R.; Zhang, T.; Zhou, Y.; Zhou, Z.; Zhuo, Y.; Gong, N.; Liu, J.; Ren, S.; Wu, R.; Shen, B.; Li, S.; Niu, Y.; Ji, W.

10.1101/588913 — immunology — Posted on 2019-03-25

752 Polymorphisms in the vitamin D system and mortality - The Tromso study

Jorde, R.; Wilsgaard, T.; Grimnes, G.

10.1101/588871 — genetics — Posted on 2019-03-25

753 Information decomposition of multichannel EMG to map functional interactions in the distributed motor system

Boonstra, T. W.; Faes, L.; Kerkman, J. N.; Marinazzo, D.

10.1101/587949 — neuroscience — Posted on 2019-03-25

754 Inter-joint and temporal coordination change in very slow walking

Little, V. L.; McGuirk, T. E.; Patten, C.

10.1101/588095 — neuroscience — Posted on 2019-03-25

755 Analyzing dynamic decision-making models using Chapman-Kolmogorov equations

Barendregt, N. W.; Josic, K.; Kilpatrick, Z.

10.1101/588087 — neuroscience — Posted on 2019-03-25

756 Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization

Lamelza, P.; Young, J. M.; Noble, L. M.; Isakharov, A.; Palanisamy, M.; Rockman, M. V.; Malik, H. S.; AILION, M.

10.1101/588152 — evolutionary biology — Posted on 2019-03-25

757 Segregation of floricolous ants along latitudinal and urbanization gradients

Vergnes, A.; Rome, Q.; Gayral, I.; Fontaine, C.

10.1101/588186 — ecology — Posted on 2019-03-25

758 SSVEP as a no-report paradigm to capture phenomenal experience of complex visual images

de Heering, A.; Beauny, A.; Vuillaume, L.; Salvesen, L.; Cleeremans, A.

10.1101/588236 — neuroscience — Posted on 2019-03-25

759 Ubiquinone biosynthesis over the entire O2 range: characterization of a conserved, O2-independent pathway

Pelosi, L.; Vo, C.-D.-T.; Abby, S.; Loiseau, L.; Rascalou, B.; Hajj Chehade, M.; Faivre, B.; Gousse, M.; Chenal, C.; Touati, N.; Binet, L.; Cornu, D.; Fyfe, C. D.; Fontecave, M.; Barras, F.; Murielle, L.; Pierrel, F.

10.1101/587956 — microbiology — Posted on 2019-03-25

760 Genomic acquisitions in emerging populations of Xanthomonas vasicola pv. vasculorum infecting corn in the U.S. and Argentina

Perez Quintero, A. L.; Ortiz-Castro, M.; Wu, G.; Lang, J. M.; Liu, S.; Chapman, T. A.; Chang, C.; Ziegle, J.; Peng, Z.; White, F. F.; Plazas, M. C.; Leach, J. E.; Broders, K.

10.1101/587915 — microbiology — Posted on 2019-03-25

761 Predicting Drug Protein Interaction using Quasi-Visual Question Answering System

Zheng, S.; Li, Y.; Chen, S.; Xu, J.; Yang, Y.

10.1101/588178 — bioinformatics — Posted on 2019-03-25

762 Context-dependent limb movement encoding in neuronal populations of motor cortex

Omlor, W.; Sipilae, P.; Wahl, A.-S.; Luetcke, H.; Laurenczy, B.; Chen, I.-W.; Sumanovski, L. T.; van 't Hoff, M.; Bethge, P.; Voigt, F. F.; Schwab, M. E.; Helmchen, F.

10.1101/588129 — neuroscience — Posted on 2019-03-25

763 Lower Extremity Long-Latency Reflexes Differentiate Walking Function After Stroke

Banks, C. L.; Little, V. L.; Walker, E. R.; Patten, C.

10.1101/588111 — neuroscience — Posted on 2019-03-25

764 Mouse vendor influence on the bacterial and viral gut composition exceeds the effect of diet

Rasmussen, T. S.; de Vries, L.; Kot, W.; Hansen, L. H.; Castro-Mejia, J. L.; Vogensen, F. K.; Hansen, A. K.; Nielsen, D. S.

10.1101/588160 — microbiology — Posted on 2019-03-25

765 Neutral genomic signatures of host-parasite coevolution.

Zivkovic, D.; John, S.; Verin, M.; Stephan, W.; Tellier, A.

10.1101/588202 — evolutionary biology — Posted on 2019-03-25

766 Co-localization of pain and reduced intra-epidermal nerve fibre density in individuals with HIV-associated sensory neuropathy

Patel, I. G.; Kamerman, P.

10.1101/587345 — neuroscience — Posted on 2019-03-25

767 Characterizing the adaptive potential of north-western Pacific reef corals to empower conservation strategies: a role for seascape genomics

Selmoni, O.; Veronique, B.-L.; Lecellier, G.; Joost, S.

10.1101/588228 — evolutionary biology — Posted on 2019-03-25

768 Cerebellar involvement in learning to balance a cart-pole system

Ludolph, N.; Ernst, T. M.; Mueller, O. M.; Goericke, S. L.; Giese, M. A.; Timmann, D.; Ilg, W.

10.1101/586990 — neuroscience — Posted on 2019-03-25

769 A novel averaging principle provides insights in the impact of intratumoral heterogeneity on tumor progression

Leocata, M.; Lopez Alfonso, J. C.; Kavallaris, N.; Hatzikirou, H.

10.1101/584490 — systems biology — Posted on 2019-03-25

770 Neuroanatomical Correlates In Bilinguals: The Case Of Children And Elderly

Garcia-Penton, L.; Fernandez, Y.; Dunabeitia, J. A.; Perez, A.; Carreiras, M.

10.1101/586768 — neuroscience — Posted on 2019-03-25

771 Cyclophilin A protects HIV-1 from restriction by human TRIM5α

Kim, K.; Dauphin, A.; Komurlu, S.; Yurkovetskiy, L.; Diehl, W. E.; McCauley, S. M.; Carbone, C.; Selyutina, A.; Bulnes-Ramos, A.; Diaz-Griffero, F.; Strambio-De-Castillia, C.; Campbell, E. M.; Luban, J.

10.1101/587907 — microbiology — Posted on 2019-03-25

772 Yellow Fever Vaccine Protects Resistant and Susceptible Mice Against Zika Virus Infection

Vicente, A. C.; Guedes-da-Silva, F. H.; Dumard, C. H.; Ferreira, V. N. S.; da Costa, I. P. S.; Machado, R. A.; Barros-Aragao, F. G. Q.; Neris, R. L. S.; Dos-Santos, J. S.; Assuncao-Miranda, I.; Figueiredo, C. P.; Dias, A. A.; Gomes, A. M. O.; de Matos Guedes, H. L.; Oliveira, A. C.; Silva, J. L.

10.1101/587444 — immunology — Posted on 2019-03-25

773 Proteomics analysis of extracellular matrix remodeling during zebrafish heart regeneration

Garcia-Puig, A.; Mosquera, J. L.; Jimenez-Delgado, S.; Garcia-Pastor, C.; Jorba, I.; Navajas, D.; Canals, F.; Raya, A.

10.1101/588251 — developmental biology — Posted on 2019-03-25

774 MuStARD: Deep Learning for intra- and inter-species scanning of functional genomic patterns

Georgakilas, G. K.; Grioni, A.; Liakos, K. G.; Malanikova, E.; Plessas, F. C.; Alexiou, P.

10.1101/547679 — bioinformatics — Posted on 2019-03-25

775 HAVE IT, KNOW IT, BUT DO NOT SHOW IT: EXAMINING PHYSIOLOGICAL AROUSAL, ANXIETY, AND FACIAL EXPRESSIONS OVER THE COURSE OF A SOCIAL SKILLS INTERVENTION FOR AUTISTIC ADOLESCENTS

10.1101/582676 — bioinformatics — Posted on 2019-03-25

776 A new cryo-EM system for electron 3D crystallography by eEFD

Yonekura, K.; Ishikawa, T.; Maki-Yonekura, S.

10.1101/588046 — molecular biology — Posted on 2019-03-25

777 AluMine: alignment-free method for the discovery of polymorphic Alu element insertions

Puurand, T.; Kukushkina, V.; Pajuste, F.-D.; Remm, M.

10.1101/588434 — genomics — Posted on 2019-03-25

778 Global biogeographical regions of freshwater fish species

Leroy, B.; Dias, M. S.; Giraud, E.; Hugueny, B.; Jezequel, C.; Leprieur, F.; Oberdorff, T.; Tedesco, P. A.

10.1101/319566 — ecology — Posted on 2019-03-25

779 Multiscale analysis of acne connects molecular subnetworks with disease status

10.1101/587857 — systems biology — Posted on 2019-03-25

780 Ontogeny and expression profiles of steroid hormone receptors in a mouse model of endometriosis

Mishra, A.; Galvankar, M.; Singh, N.; Vaidya, S.; Chaudhari, U.; Modi, D.

10.1101/588392 — pathology — Posted on 2019-03-25

781 Do questionnaires reflect their purported cognitive functions?

Clark, I. A.; Maguire, E. A.

10.1101/583690 — neuroscience — Posted on 2019-03-25

782 Inter-subject pattern analysis: a straightforward and powerful scheme for group-level MVPA.

Wang, Q.; Cagna, B.; Chaminade, T.; Takerkart, S.

10.1101/587899 — neuroscience — Posted on 2019-03-25

783 Differential dynamics of microbial community networks help identify microorganisms interacting with residue-borne pathogens: the case of Zymoseptoria tritici in wheat

Kerdraon, L.; Barret, M.; Laval, V.; Suffert, F.

10.1101/587667 — microbiology — Posted on 2019-03-25

784 Adult Drosophila Muscle Morphometry through MicroCT reveals dynamics during aging

Chaturvedi, D.; Prabhakar, S.; Aggarwal, A.; VijayRaghavan, K.

10.1101/587733 — developmental biology — Posted on 2019-03-25

785 Stringent structural plasticity of dendritic spines revealed by two-photon glutamate uncaging in adult mouse neocortex in vivo

Noguchi, J.; Nagaoka, A.; Hayama, T.; Ucar, H.; Yagishita, S.; Takahashi, N.; Kasai, H.

10.1101/577742 — neuroscience — Posted on 2019-03-25

786 Encoding Variability: When Pattern Reactivation Does Not Benefit Context Memory

Sievers, C.; Smith, F. W.; Saada, J.; Simons, J. S.; Renoult, L.

10.1101/586446 — neuroscience — Posted on 2019-03-25

787 Morphological variation in Blommersia pelvic shape coincides with muscular architecture and parallels genus phylogenetic evolution

Santos-Santos, J. H.; Guinovart-Castan, M.; Vieites, D.

10.1101/586248 — evolutionary biology — Posted on 2019-03-25

788 The mechanisms of dynamin-actin interaction

Zhang, R.; Gerassimov, N.; Lee, D. M.; Jimah, J. R.; Kim, S.; Luvsanjav, D.; Winkelman, J.; Mettlen, M.; Abrams, M. E.; Kalia, R.; Keene, P.; Pandey, P.; Ravaux, B.; Kim, J. H.; Ditlev, J. A.; Zhang, G.; Rosen, M. K.; Frost, A.; Alto, N. M.; Gardel, M.; Schmid, S. L.; Hinshaw, J. E.; Chen, E. H.

10.1101/586461 — cell biology — Posted on 2019-03-25

789 Fully-sensitive Seed Finding in Sequence Graphs Using a Hybrid Index

Ghaffaari, A.; Marschall, T.

10.1101/587717 — bioinformatics — Posted on 2019-03-25

790 In vivo feasibility study of the use of porous polyhedral oligomeric silsesquioxane implants in partial laryngeal reconstruction.

Birchall, M. A.; Hermann, P.; Sibbons, P.

10.1101/587691 — bioengineering — Posted on 2019-03-25

791 Co-developing climate services for public health: stakeholder needs and perceptions for the prevention and control of Aedes-transmitted diseases in the Caribbean.

Stewart-Ibarra, A. M.; Romero, M.; Hinds, A. Q. J.; Lowe, R.; Mahon, R.; Van Meerbeeck, C. J.; Rollock, L.; Gittens-St. Hillaire, M.; St. Ville, S.; Ryan, S. J.; Trotman, A. R.; Borbor-Cordova, M. J.

10.1101/587188 — scientific communication and education — Posted on 2019-03-25

792 Human lateral Frontal Pole contributes to control over social-emotional behaviour

Bramson, B.; Folloni, D.; Verhagen, L.; Hartogsveld, B.; Mars, R. B.; Toni, I.; Roelofs, K.

10.1101/584896 — neuroscience — Posted on 2019-03-25

793 Carrion flies as sentinels for monitoring rabbit calicivirus activity in Australia

Hall, R. N.; Huang, N.; Roberts, J. M. K.; Strive, T.

10.1101/585885 — microbiology — Posted on 2019-03-25

794 A seventeenth-century Mycobacterium tuberculosis genome supports a Neolithic emergence of the Mycobacterium tuberculosis complex

Sabin, S.; Herbig, A.; Vagene, A. J.; Ahlström, T.; Bozovic, G.; Arcini, C.; Kühnert, D.; Bos, K. I.

10.1101/588277 — genomics — Posted on 2019-03-25

795 GWAS of 19,629 individuals identifies novel genetic variants for regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

Zhao, B.; Luo, T.; Li, T.; Li, Y.; Zhang, J.; Shan, Y.; Wang, X.; Yang, L.; Zhou, F.; Zhu, Z.; Zhu, H.

10.1101/586339 — genetics — Posted on 2019-03-25

796 Extraordinary claims require extraordinary evidence in the case of asserted mtDNA biparental inheritance

Salas, A.; Schoenherr, S.; Bandelt, H. J.; Gomez-Carballa, A.; Weissensteiner, H.

10.1101/585752 — genetics — Posted on 2019-03-25

797 Genome-wide association study of Parkinson's disease progression biomarkers in 12 longitudinal patients' cohorts

Iwaki, H.; Blauwendraat, C.; Leonard, H. L.; Kim, J. J.; Liu, G.; Maple-Grodem, J.; Corvol, J.-C.; Pihlstrom, L.; van Nimwegen, M.; Hutten, S. J.; Nguyen, K.-D. H.; Rick, J.; Eberly, S.; Faghri, F.; Auinger, P.; Scott, K. M.; Wijeyekoon, R.; Van Deerlin, V. M.; Hernandez, D.; Gibbs, J. R.; Chitrala, K. N.; Day-Williams, A. G.; Brice, A.; Alves, G.; Noyce, A. J.; Tysnes, O.-B.; Evans, J.; Breen, D. P.; Estrada, K.; Wegel, C. E.; Danjou, F.; Simon, D. K.; Andreassen, O. A.; Ravina, B.; Toft, M.; Heutink, P.; Bloem, B. R.; Weintraub, D.; Barker, R. A.; Williams-Gray, C. H.; van de Warrenburg, B.

10.1101/585836 — genetics — Posted on 2019-03-25

798 On the move: Redox-dependent protein relocation

Foyer, C. H.; Baker, A.; Wright, M.; Sparkes, I.; Mhamdi, A.; Van Breusegem, F.; Schippers, J.

10.1101/588269 — cell biology — Posted on 2019-03-25

799 tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing

Krause, M.; Niazi, A. M.; Labun, K.; Müller, F. S.; Torres Cleuren, Y. N.; Valen, E.

10.1101/588343 — bioinformatics — Posted on 2019-03-25

800 Characterization of pathology-inducing α-synuclein species from human diseased brain tissue

Graef, J. D.; Hoque, N.; Polson, C.; Yang, L.; Iben, L.; Cao, Y.; Devidze, N.; Ahlijanian, M. K.; Meredith, J.

10.1101/588335 — neuroscience — Posted on 2019-03-25

801 Enriching hippocampal memory function in older adults through video games

Clemenson, G. D.; Stark, S. M.; Rutledge, S. M.; Stark, C. E.

10.1101/587006 — neuroscience — Posted on 2019-03-25

802 Prenatal Exposure to Environmental Chemicals Modulates Serum Phospholipids in Newborn Infants, Increasing Later Risk of Type 1 Diabetes

McGlinchey, A.; Sinioja, T.; Lamichhane, S.; Bodin, J.; Siljander, H.; Geng, D.; Carlsson, C.; Duberg, D.; Ilonen, J.; Virtanen, S. M.; Dirven, H.; Bentsen, H. F.; Zimmer, K.; Nygaard, U. C.; Oresic, M.; Knip, M.; Hyotylainen, T.

10.1101/588350 — molecular biology — Posted on 2019-03-25

803 First record of the endophytic bacteria of Deschampsia antarctica E. Desv. from two distant localities of the maritime Antarctica

Podolich, O.; Parnikoza, I.; Voznyuk, T.; Zubova, G.; Zaets, I.; Miryuta, N.; Myryuta, G.; Poronnik, O.; Kozeretska, I.; Kunakh, V.; Pirttila, A.-M.; Kozyrovska, N.

10.1101/586099 — microbiology — Posted on 2019-03-25

804 Treatment of Murine Lupus with TIGIT-Ig

Liu, S.; Sun, L.; Wang, C.; Cui, Y.; Ling, Y.; Li, T.; Lin, F.; Fu, W.; Ding, M.; Zhang, S.; Lei, C.; Hu, S.

10.1101/586321 — immunology — Posted on 2019-03-25

805 Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

Stevenson, A. J.; McCartney, D. L.; Hillary, R. F.; Redmond, P.; Taylor, A. M.; Zhang, Q.; McRae, A. F.; Spires-Jones, T. L.; McIntosh, A. M.; Deary, I. J.; Marioni, R. E.

10.1101/588293 — genomics — Posted on 2019-03-25

806 Increased genetic marker density reveals high levels of admixture between red deer and introduced sika in Kintyre, Scotland

McFarlane, S. E.; Hunter, D. C.; Senn, H. V.; Smith, S. L.; Holland, R.; Huisman, J.; Pemberton, J. M.

10.1101/588327 — evolutionary biology — Posted on 2019-03-25

807 Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia

Milne, P.; Wilhelm-Benartzi, C.; Grunwald, M. R.; Bigley, V.; Publicover, A.; Pagan, S.; Marr, H.; Jones, G.; Dickinson, A.; Grech, A.; Burnett, A.; Russell, N.; Levis, M.; Knapper, S.; Collin, M.

10.1101/588319 — cancer biology — Posted on 2019-03-25

808 Transfer of Xanthomonas campestris pv. arecae, and Xanthomonas campestris pv. musacearum to Xanthomonas vasicola (Vauterin) as Xanthomonas vasicola pv. arecae comb. nov., and Xanthomonas vasicola pv. musacearum comb. nov. and description of Xanthomonas vasicola pv. vasculorum pv. nov.

Studholme, D. J.; Wicker, E.; Aspin, A.; Bogdanove, A.; Broders, K.; Dubrow, Z.; Grant, M.; Jones, J. B.; Karamura, G.; Lang, J.; Leach, J.; Abrare, S. M.; Mahuku, G.; Nakato, G. V.; Coutinho, T.; Smith, J.; Bull, C.

10.1101/571166 — microbiology — Posted on 2019-03-25

809 Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

Vögtle, T.; Sharma, S.; Mori, J.; Nagy, Z.; Semeniak, D.; Geer, M. J.; Smith, C. W.; Lane, J.; Pollack, S.; Lassila, R.; Jouppila, A.; Barr, A. J.; Ogg, D. J.; Howard, T. D.; McMiken, H. J.; Warwicker, J.; Geh, C.; Rowlinson, R.; Abbott, W. M.; Schulze, H.; Wright, G. J.; Mazharian, A.; Fütterer, K.; Rajesh, S.; Douglas, M. R.; Senis, Y. A.

10.1101/584698 — biochemistry — Posted on 2019-03-25

810 Transcriptional crosstalk varies between regulatory strategies

Grah, R.; Friedlander, T.

10.1101/372672 — systems biology — Posted on 2019-03-25

811 Detecting RyR clusters with CaCLEAN: influence of spatial distribution and structural heterogeneity

Ladd, D.; Tilunaite, A.; Soeller, C.; Roderick, H. L.; Crampin, E.; Rajagopal, V.

10.1101/549683 — bioengineering — Posted on 2019-03-25

812 The functional repertoire encoded within the native microbiome of the model nematode Caenorhabditis elegans

Zimmermann, J.; Obeng, N.; Yang, W.; Pees, B.; Petersen, C.; Waschina, S.; Kissoyan, K. A.; Aidley, J.; Hoeppner, M. P.; Bunk, B.; Sproer, C.; Leippe, M.; Dierking, K.; Kaleta, C.; Schulenburg, H.

10.1101/554345 — microbiology — Posted on 2019-03-25

813 The convoluted evolutionary history of the capped-golden langur lineage (Cercopithecidae: Colobinae)- concatenation versus coalescent analyses

Arekar, K.; Parigi, A.; Karanth, K. P.

10.1101/508929 — evolutionary biology — Posted on 2019-03-25

814 WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling

Song, Z.; Sun, X.; Xia, Z.; Jia, Y.; Zhu, J.; Fang, C.; Yang, H.; Wang, J.

10.1101/575100 — bioinformatics — Posted on 2019-03-25

815 CRK2 enhances salt tolerance by regulating callose deposition in connection with PLDα1

Hunter, K.; Kimura, S.; Rokka, A.; Tran, C.; Toyota, M.; Kukkonen, J.; Wrzaczek, M.

10.1101/487009 — plant biology — Posted on 2019-03-25

816 High precision automated detection of labeled nuclei in Gigapixel resolution image data of Mouse Brain

Das, S.; Jayakumar, J.; Bannerjee, S.; Ramaswamy, J.; Vangala, V.; Ram, K.; Mitra, P. P.

10.1101/252247 — neuroscience — Posted on 2019-03-25

817 Widespread methane formation by Cyanobacteria in aquatic and terrestrial ecosystems

Bizic-Ionescu, M.; Klintzch, T.; Ionescu, D.; Hindiyeh, M. Y.; Guenthel, M.; Muro Pastor, A. M.; Eckert, W.; Keppler, F.; Grossart, H.-P.

10.1101/398958 — microbiology — Posted on 2019-03-25

818 The inducible response of the nematode Caenorhabditis elegans to members of its natural microbiome across development and adult life

Yang, W.; Petersen, C.; Pees, B.; Zimmermann, J.; Waschina, S.; Dirksen, P.; Rosenstiel, P.; Tholey, A.; Leippe, M.; Dierking, K.; Kaleta, C.; Schulenburg, H.

10.1101/554758 — evolutionary biology — Posted on 2019-03-25

819 Model-based assessment of public health impact and cost-effectiveness of dengue vaccination following screening for prior exposure

Espana, G.; Yao, Y.; Anderson, K. B.; Fitzpatrick, M. C.; Smith, D. L.; Morrison, A. C.; Wilder-Smith, A.; Scott, T. W.; Perkins, A.

10.1101/367060 — epidemiology — Posted on 2019-03-25

820 MEXCOWalk: Mutual Exclusion and Coverage Based Random Walk to Identify Cancer Modules

Ahmed, R.; Baali, I.; Erten, C.; Hoxha, E.; Kazan, H.

10.1101/547653 — bioinformatics — Posted on 2019-03-25

821 Fast and flexible simulation and parameter estimation for synthetic biology using bioscrape

Swaminathan, A.; Poole, W.; Hsiao, V.; Murray, R. M.

10.1101/121152 — synthetic biology — Posted on 2019-03-25

822 Phenotyping and molecular marker analysis of WH1105 and Kharchia 65 backcrosses and F4 progenies for salinity tolerance

Varsha, V.; Yashveer, S.; Singh, V.; Pratap, S.

10.1101/586941 — plant biology — Posted on 2019-03-24

823 The effects of cerebellar transcranial direct current stimulation on the cognitive stage of sequence learning

Ballard, H. K.; Goen, J. R. M.; Maldonado, T.; Bernard, J. A.

10.1101/588012 — neuroscience — Posted on 2019-03-24

824 NSD2 overexpression drives clustered chromatin and transcriptional changes in insulated domains

Lhoumaud, P.; Badri, S.; Rodriguez-Hernaez, J.; Sethia, G.; Kloetgen, A.; Cornwell, M.; Bhattacharyya, S.; Ay, F.; Bonneau, R.; Tsirigos, A.; Skok, J. A.

10.1101/587931 — genomics — Posted on 2019-03-24

825 Single-step genome-wide association study for resistance to Piscirickettsia salmonis in rainbow trout (Oncorhynchus mykiss)

Marin Nahuelpi, R. I.; Barria, A.; Caceres Refusta, P.; Lopez, M.-E.; Bassini, L.; Lhorente Caussade, J. P.; Yanez, J. M.

10.1101/587535 — genomics — Posted on 2019-03-24

826 Peaceful behaviour: a strategy employed by an obligate nest invader to avoid conflict with its host species

Hugo, H.; Cristaldo, P. F.; DeSouza, O.

10.1101/587592 — animal behavior and cognition — Posted on 2019-03-24

827 MS Atlas - A molecular map of brain lesion stages in progressive multiple sclerosis

Frisch, T.; Elkjaer, M. L.; Reynolds, R.; Michel, T. M.; Kacprowski, T.; Burton, M.; Kruse, T. A.; Thomassen, M.; Baumbach, J.; Illes, Z.

10.1101/584920 — systems biology — Posted on 2019-03-24

828 Modulation of visual cortex by hippocampal signals

Fournier, J.; Saleem, A. B.; Diamanti, E. M.; Wells, M. J.; Harris, K. D.; Carandini, M.

10.1101/586917 — neuroscience — Posted on 2019-03-24

829 Bidirectional FtsZ filament treadmilling promotes membrane constriction via torsional stress

Ramirez-Diaz, D. A.; Merino-Salomon, A.; Heymann, M.; Schwille, P.

10.1101/587790 — biophysics — Posted on 2019-03-24

830 Genetic dissection of cell wall defects and the strigolactone pathway in Arabidopsis.

Ramirez, V.; Pauly, M.

10.1101/586388 — plant biology — Posted on 2019-03-24

831 On the relationship between LFP beta oscillation amplitude and firing rate of individual neurons in monkey motor cortex

Confais, J.; Malfait, N.; Brochier, T.; Riehle, A.; Kilavik, B. E.

10.1101/586727 — neuroscience — Posted on 2019-03-24

832 Codon Optimality Confers GC-Rich-Induced Stability to mRNAs in Humans

Hia, F.; Yang, S. F.; Shichino, Y.; Yoshinaga, M.; Murakawa, Y.; Vandenbon, A.; Fukao, A.; Fujiwara, T.; Landthaler, M.; Natsume, T.; Adachi, S.; Iwasaki, S.; Takeuchi, O.

10.1101/585992 — molecular biology — Posted on 2019-03-24

833 ANP32A and ANP32B are key factors in the Rev dependent CRM1 pathway for nuclear export of HIV-1 unspliced mRNA

Wang, Y.; Zhang, H.; Na, L.; Du, C.; Zhang, Z.; Zheng, Y.; Wang, X.

10.1101/559096 — microbiology — Posted on 2019-03-24

834 Machine Learning-Assisted Digital PCR and Melt Enables Broad Bacteria Identification and Pheno-Molecular Antimicrobial Susceptibility Test

Athamanolap, P.; Hsieh, K.; O'Keefe, C. M.; Zhang, Y.; Yang, S.; Wang, J.

10.1101/587543 — bioengineering — Posted on 2019-03-24

835 The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell autonomous level and by collaborative exclusion

Lopez-Jimenez, A. T.; Hagedorn, M.; Delince, M. J.; McKinney, J.; Soldati, T.

10.1101/586263 — microbiology — Posted on 2019-03-24

836 Molecular dissection of the structural and nonstructural proteins of spanish-1918 Influenza, pandemic-2009, and bird flu viruses

Mahardika, G. N.; Suartha, N. I.; Kencana, Y. G. A.; Suardana, I. B. K.; Budayanti, N. S.

10.1101/585778 — microbiology — Posted on 2019-03-24

837 A multi-omic cohort as a reference point for promoting a healthy human gut microbiome

Jie, Z.; Liang, S.; Ding, Q.; Tang, S.; Li, F.; Wang, D.; Lin, Y.; Chen, P.; Cai, K.; Rao, W.; Liao, Y.; Zhou, D.; Qiu, X.; Chen, X.; Zi, J.; Wang, X.; Zhang, W.; Zhang, T.; Xiao, L.; Yang, H.; Wang, J.; Hou, Y.; Liu, X.; Kristiansen, K.; Zhong, H.; Jia, H.; Xu, X.

10.1101/585893 — microbiology — Posted on 2019-03-24

838 Supervised dimension reduction for large-scale \"omics\" data with censored survival outcomes under possible non-proportional hazards

Spirko-Burns, L.; Devarajan, K.

10.1101/586529 — bioinformatics — Posted on 2019-03-24

839 Automated reconstruction of all gene histories in large bacterial pangenome datasets and search for co-evolved gene modules with Pantagruel

Lassalle, F.; Veber, P.; Jauneikaite, E.; Didelot, X.

10.1101/586495 — bioinformatics — Posted on 2019-03-24

840 Inhibition of arterivirus RNA synthesis by cyclophilin inhibitors is counteracted by mutations in replicase transmembrane subunits

De Wilde, A. H.; Boomaars-van der Zanden, L.; de Jong, A. W. M.; Barcena, M.; Snijder, E. J.; Posthuma, C. C.

10.1101/587261 — microbiology — Posted on 2019-03-24

841 Generic and context-dependent gene modulations during Hydra whole body regeneration

Galliot, B.; Wenger, Y.; Buzgariu, W.; Perruchoud, C.; Loichot, G.

10.1101/587147 — developmental biology — Posted on 2019-03-24

842 Modeling the ballistic-to-diffusive transition in nematode motility reveals variation in exploratory behavior across species

Helms, S. J.; Rozemuller, W. M.; Costa, A. C.; Avery, L.; Stephens, G. J.; Shimizu, T. S.

10.1101/587618 — biophysics — Posted on 2019-03-24

843 Negative calorie foods: An empirical examination of what is fact or fiction

Buddemeyer, K. M.; Alexander, A. E.; Secor, S. M.

10.1101/586958 — physiology — Posted on 2019-03-24

844 Anatomo-functional correlates of auditory development in infancy

Adibpour, P.; Lebenberg, J.; Kabdebon, C.; Dehaene-Lambertz, G.; Dubois, J.

10.1101/585448 — neuroscience — Posted on 2019-03-24

845 Identification of blaGIM-1 in Acinetobacter variabilis isolated from the hospital environment in Tamil Nadu, India

Manohar, P.; Ragavi, M.; Augustine, A.; MV, H.; Nachimuthu, R.

10.1101/586164 — microbiology — Posted on 2019-03-24

846 Vesicle-associated Pseudomonas aeruginosa leucine aminopeptidase modulates bacterial biofilms grown on host cellular substrates

Esoda, C.; Kuehn, M.

10.1101/587279 — microbiology — Posted on 2019-03-24

847 Identifying suitable Listeria innocua strains as surrogates for Listeria monocytogenes for horticultural products

Mohan, V.; Wibisono, R.; de Hoop, L.; Summers, G.; Fletcher, G. C.

10.1101/586016 — microbiology — Posted on 2019-03-24

848 Global Modulation in DNA Epigenetics during Pro-Inflammatory Macrophage Activation

JAIN, N.; Shahal, T.; Gabrieli, T.; Gilat, N.; Torchinsky, D.; Michaeli, Y.; VOGEL, V.; Ebenstein, Y.

10.1101/587311 — immunology — Posted on 2019-03-24

849 Comparative genomics guides elucidation of vitamin B12 biosynthesis in novel human associated Akkermansia

Kirmiz, N.; Galindo, K.; Cross, K.; Luna, E.; Rhoades, N.; Podar, M.; Flores, G.

10.1101/587527 — genomics — Posted on 2019-03-24

850 Genetic dissection of the redundant and divergent functions of histone chaperone paralogs in yeast

Savic, N.; Shortill, S.; Bilenky, M.; Dilworth, D.; Hirst, M.; Nelson, C. J.

10.1101/586347 — genetics — Posted on 2019-03-24

851 The planktonic protist interactome: emerging trends after a century of research

Bjorbaekmo, M. F. M.; Evenstad, A.; Rosaeg, L. L.; Krabberod, A. K.; Logares, R.

10.1101/587352 — ecology — Posted on 2019-03-24

852 From bud formation to flowering: transcriptomic state defines the cherry developmental phases of sweet cherry bud dormancy

Vimont, N.; Fouche, M.; Campoy, J. A.; Tong, M.; Arkoun, M.; Yvin, J.-C.; Wigge, P. A.; Dirlewanger, E.; Cortijo, S.; Wenden, B.

10.1101/586651 — plant biology — Posted on 2019-03-24

853 Meningitis pathogens evade immune responses by thermosensing

Eichner, H.; Spelmink, L.; Pathak, A.; Henriques Normark, B.; Loh, E.

10.1101/586131 — microbiology — Posted on 2019-03-24

854 A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells

Abu-Shah, E.; Demetriou, P.; Mayya, V.; Balint, S.; Kutuzov, M. A.; Dushek, O.; Dustin, M. L.

10.1101/587386 — immunology — Posted on 2019-03-24

855 NOD1 mediates non-canonical inflammasome processing of interleukin-18 in epithelial cells to Helicobacter pylori infection.

Tran, L. S.; Ying, L.; D'Costa, K.; Wray-McCann, G.; Kerr, G.; Le, L.; Allison, C. C.; Ferrand, J.; Chaudhry, H.; Emery, J.; De Paoli, A.; Creed, S.; Kaparakis-Liaskos, M.; Como, J.; Dowling, J.; Johanesen, P. A.; Kufer, T. A.; Pedersen, J. S.; Mansell, A.; Philpott, D. J.; Elgass, K.; Abud, H. E.; Nachbur, U.; Croker, B. A.; Masters, S. L.; Ferrero, R. L.

10.1101/587212 — immunology — Posted on 2019-03-24

856 Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritis

Chang, H.-H.; Ho, C.-H.; Tomita, B.; Silva, A. A.; Sparks, J. A.; Karlson, E. W.; Rao, D. A.; Lee, Y. C.; Ho, I.-C.

10.1101/586982 — immunology — Posted on 2019-03-24

857 Membrane association of VAMP2 SNARE motif in cells and its regulation by different lipid phases of synaptic vesicle membrane

Wang, C.; Tu, J.; Zhang, S.; Cai, B.; Liu, Z.; Hou, S.; Liu, Z.; Diao, J.; Zhu, Z.-J.; Liu, C.; Li, D.

10.1101/587766 — biophysics — Posted on 2019-03-24

858 Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence

McCulloch, L.; Allan, S. M.; Smith, C. J.; McColl, B. W.

10.1101/587881 — immunology — Posted on 2019-03-24

859 A phenotypically plastic magic trait promoting reproductive isolation in sticklebacks?

Garduno-Paz, M.; Huntingford, F.; Adams, C.

10.1101/587675 — evolutionary biology — Posted on 2019-03-24

860 Global mammalian zooregions reveal a signal of past human impacts

Rueda, M.; Gonzalez Suarez, M.; Revilla, E.

10.1101/586313 — ecology — Posted on 2019-03-24

861 DeepTRIAGE: Interpretable and Individualised BiomarkerScores using Attention Mechanism for the Classification of Breast Cancer Sub-types

Beykikhoshk, A.; Quinn, T. P.; Lee, S. C.; Tran, T.; Venkatesh, S.

10.1101/533406 — biophysics — Posted on 2019-03-24

862 Increased oral Epstein-Barr virus shedding with HIV-1 co-infection is due to a combination of B cell activation and impaired cellular immune control

Byrne, C. M.; Johnson, C.; Orem, J.; Okuku, F.; Huang, M.-L.; Selke, S.; Wald, A.; Corey, L.; Schiffer, J. T.; Casper, C.; Coombs, D.; Gantt, S.

10.1101/587063 — pathology — Posted on 2019-03-24

863 Cerebral Blood Flow Increases Across Early Childhood

Paniukov, D.; Lebel, R. M.; Giesbrecht, G.; Lebel, C.

10.1101/587139 — neuroscience — Posted on 2019-03-24

864 A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems

Vogel, J.; La Joie, R.; Grothe, M. J.; Diaz-Papkovich, A.; Doyle, A.; Vachon-Presseau, E.; Lepage, C.; Vos de Wael, R.; Iturria-Medina, Y.; Bernhardt, B.; Rabinovici, G. D.; Evans, A. C.

10.1101/587071 — neuroscience — Posted on 2019-03-24

865 Keep your hands apart: independent representations of ipsilateral and contralateral forelimbs in primary motor cortex

Heming, E.; Cross, K.; Takei, T.; Cook, D. J.; Scott, S. H.

10.1101/587378 — neuroscience — Posted on 2019-03-24

866 Enriching hippocampal memory function in older adults through real-world exploration

Kolarik, B. S.; Stark, S. M.; Rutledge, S. M.; Stark, C. E.

10.1101/586974 — neuroscience — Posted on 2019-03-24

867 Revealing virulence potential of clinical and environmental Aspergillus fumigatus isolates using Whole-genome sequencing

Puertolas-Balint, F.; Rossen, J. W.; Oliveira dos Santos, C.; Chlebowicz, M. A.; Raangs, E.; van Putten, M. L.; Sola-Campoy, P. J.; Han, L.; Schmidt, M.; Garcia-Cobos, S.

10.1101/587402 — microbiology — Posted on 2019-03-24

868 Transcriptome-based prediction of complex traits in maize

Azodi, C.; Pardo, J.; VanBuren, R.; de los Campos, G.; Shiu, S.-H.

10.1101/587121 — genetics — Posted on 2019-03-24

869 Population divergence time estimation using individual lineage label switching

Beerli, P.; Ashki, H.; Mashayekhi, S.; Palczewski, M.

10.1101/587832 — evolutionary biology — Posted on 2019-03-24

870 Bacterial biodiversity drives the evolution of CRISPR-based phage resistance in Pseudomonas aeruginosa

Alseth, E. O.; Pursey, E.; Lujan, A.; McLeod, I.; Rollie, C.; Westra, E.

10.1101/586115 — evolutionary biology — Posted on 2019-03-24

871 A Divide-and-Conquer Method for Scalable Phylogenetic Network Inference from Multi-locus Data

Zhu, J.; Liu, X.; Ogilvie, H.; Nakhleh, L.

10.1101/587725 — evolutionary biology — Posted on 2019-03-24

872 Progressive recruitment of distal MEC-4 channels determines touch response strength in C. elegans

Katta, S.; Sanzeni, A.; Vergassola, M.; Goodman, M. B.

10.1101/587014 — neuroscience — Posted on 2019-03-24

873 Endosymbiotic bacteria are prevalent and diverse in agricultural spiders

White, J. A.; Styer, A.; Rosenwald, L. C.; Curry, M. M.; Welch, K. D.; Athey, K. J.; Chapman, E. G.

10.1101/586750 — microbiology — Posted on 2019-03-24

874 A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring

Altman, M. C.; Baldwin, N.; Whalen, E.; Al-Shaikhly, T.; Presnell, S.; Khaenam, P.; Gersuk, V. H.; Chiche, L.; Jourde-Chiche, N.; Phillips, T.; Klintmalm, G.; O'Garra, A.; Berry, M.; Bloom, C.; Wilkinson, R. J.; Graham, C. M.; Lipman, M.; Lertmemongkolchai, G.; Kheradmand, F.; Mejias, A.; Ramilo, O.; Palucka, K.; Pascual, V.; Banchereau, J.; Chaussabel, D.

10.1101/587295 — immunology — Posted on 2019-03-24

875 Augmentation of T-cell activation by oscillatory forces and engineered antigen-presenting cells

Majedi, F. S.; Hasani-Sadrabadi, M. M.; Thauland, T. J.; Li, S.; Bouchard, L.-S.; Butte, M.

10.1101/580704 — immunology — Posted on 2019-03-24

876 Diversity and relative abundance of Collembola in a wheat (Triticum aestivum) field at Aligarh

Abbas, M. J.; Parwez, H. J.

10.1101/580811 — ecology — Posted on 2019-03-24

877 Global distribution of earthworm diversity

Phillips, H. R. P.; Guerra, C. A.; Bartz, M. L. C.; Briones, M. J. I.; Brown, G.; Ferlian, O.; Gongalsky, K. B.; Krebs, J.; Orgiazzi, A.; Schwarz, B.; Bachs, E. M.; Bennett, J.; Brose, U.; Decaens, T.; De Vries, F. T.; Konig-Ries, B.; Lavelle, P.; Loreau, M.; Mathieu, J.; Mulder, C.; van der Putten, W.; Ramirez, K. S.; Rillig, M. C.; Russell, D.; Rutgers, M.; Thakur, M. P.; Wall, D.; Wardle, D.; sWorm Data Providers, ; Cameron, E.; Eisenhauer, N.

10.1101/587394 — ecology — Posted on 2019-03-24

878 Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

Starrett, G. J.; Thakuria, M.; Chen, T.; Marcelus, C.; Cheng, J.; Nomburg, J.; Thorner, A. R.; Slevin, M. K.; Powers, W.; Burns, R. T.; Perry, C.; Piris, A.; Kuo, F. C.; Rabinowits, G.; Giobbie-Hurder, A.; MacConaill, L. E.; DeCaprio, J. A.

10.1101/587626 — cancer biology — Posted on 2019-03-24

879 Cell BLAST: Searching large-scale scRNA-seq database via unbiased cell embedding

Cao, Z.-J.; Wei, L.; Lu, S.; Yang, D.-C.; Gao, G.

10.1101/587360 — bioinformatics — Posted on 2019-03-24

880 Self-Organizing Map Methodology for Sorting Differential Expression Data of MMP-9 Inhibition

St Clair, R.; Teti, M.; Knapinska, A.; Fields, G.; Hahn, W.; Barenholtz, E.

10.1101/586628 — bioinformatics — Posted on 2019-03-24

881 Formalizing metabolic-regulatory networks by hybrid automata

Liu, L.; Bockmayr, A.

10.1101/586198 — systems biology — Posted on 2019-03-24

882 Linalool acts as a fast and reversible anesthetic in Hydra

Goel, T.; Wang, R.; Martin, S.; Lanphear, E.; Collins, E.-M. S.

10.1101/584946 — pharmacology and toxicology — Posted on 2019-03-24

883 Whisker map organization in somatosensory cortex of awake, behaving mice

Wang, H. C.; LeMessurier, A. M.; Feldman, D. E.

10.1101/587634 — neuroscience — Posted on 2019-03-24

884 FcγRIIB I232T polymorphic change allosterically suppresses ligand binding

Hu, W.; Zhang, Y.; Sun, X.; Xu, L.; Xie, H.; Li, Z.; Liu, W.; Lou, J.; Chen, W.

10.1101/586487 — immunology — Posted on 2019-03-24

885 5-HT2B serotonin receptor agonist BW723C86 shapes the macrophage gene profile via AhR and impairs monocyte-to-osteoclast differentiation

Nieto, C.; Rayo, I.; de las Casas-Engel, M.; Izquierdo, E.; Alonso, B.; Vega, M. A.; Corbi, A. L.

10.1101/587709 — immunology — Posted on 2019-03-24

886 Estimating and accounting for genotyping errors in RAD-seq experiments

Bresadola, L.; Link, V.; Buerkle, A.; Lexer, C.; Wegmann, D.

10.1101/587428 — evolutionary biology — Posted on 2019-03-24

887 Estimating Diversity Through Time using Molecular Phylogenies: Old and Species-Poor Frog Families are the Remnants of a Diverse Past

Billaud, O.; Moen, D.; Parsons, T.; Morlon, H.

10.1101/586420 — evolutionary biology — Posted on 2019-03-24

888 Automated reconstruction of all gene histories in large bacterial pangenome datasets and search for co-evolved gene modules with Pantagruel

Lassalle, F.; Didelot, X.; Jauneikaite, E.; Veber, P.

10.1101/586495 — bioinformatics — Posted on 2019-03-24

889 STATegra: a comprehensive multi-omics dataset of B-cell differentiation in mouse

Gomez-Cabrero, D.; Tarazona, S.; Ferreiros-Vidal, I.; Ramirez, R. N.; Company, C.; Schmidt, A.; von Saint Paul, V.; Reijmers, T.; Marabita, F.; Rodriguez-Ubreva, J.; Garcia-Gomez, A.; Caroll, T.; Cooper, L.; Liang, Z.; Dharmalingam, G.; Balzano-Nogueira, L.; Lagani, V.; Tsamardinos, I.; Lappe, M.; Maier, D.; Westerhuis, J. A.; Thomas, T.; Imhof, A.; Ballestar, E.; Mortazavi, A.; Merkenschlager, M.; Tenger, J.; Conesa, A.

10.1101/587477 — bioinformatics — Posted on 2019-03-24

890 Genetic structure of prey populations underlies the geographic mosaic of arms race coevolution

Hague, M.; Stokes, A.; Feldman, C.; Brodie, E.; Brodie, E.

10.1101/585851 — evolutionary biology — Posted on 2019-03-24

891 Genomic landscape of the global oak phylogeny

Hipp, A. L.; Manos, P. S.; Hahn, M.; Avishai, M.; Bodenes, C.; Cavender-Bares, J.; Crowl, A.; Deng, M.; Denk, T.; Fitz-Gibbon, S.; Gailing, O.; Gonzalez-Elizondo, M. S.; Gonzalez-RodrIguez, A.; Grimm, G. W.; Jiang, X.; Kremer, A.; Lesur, I.; McVay, J. D.; Plomion, C.; RodrIguez-Correa, H.; Schulze, E.-D.; Simeone, M. C.; Sork, V. L.; Valencia-Avalos, S.

10.1101/587253 — evolutionary biology — Posted on 2019-03-24

892 ZBTB33 (Kaiso) methylated binding sites are associated with primed heterochromatin

Lin, Q. X. X.; Rebbani, K.; Jha, S.; Benoukraf, T.

10.1101/585653 — genomics — Posted on 2019-03-24

893 Real-world expectations and their affective value modulate object processing

Caplette, L.; Gosselin, F.; Mermillod, M.; Wicker, B.

10.1101/408542 — neuroscience — Posted on 2019-03-24

894 Germline features associated with immune infiltration in solid tumors

Shahamatdar, S.; He, M. X.; Reyna, M.; Gusev, A.; AlDubayan, S. H.; Van Allen, E. M.; Ramachandran, S.

10.1101/586081 — genetics — Posted on 2019-03-24

895 Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n=17,706)

Zhao, B.; Zhang, J.; Ibrahim, J.; Luo, T.; Santelli, R.; Li, Y.; Li, T.; Shan, Y.; Zhu, Z.; Zhou, F.; Liao, H.; Nichols, T.; Zhu, H.

10.1101/288555 — genetics — Posted on 2019-03-24

896 Desiccation-induced changes in recombination rate and crossover interference in Drosophila melanogaster: evidence for fitness-dependent plasticity

Aggarwal, D. D.; Rybnikov, S. R.; Cohen, I.; Frenkel, Z.; Rashkovetsky, E.; Michalak, P.; Korol, A. B.

10.1101/382259 — genetics — Posted on 2019-03-24

897 Computational Drug Recommendation Approaches toward Safe Polypharmacy

Chiang, W.-H.; Ning, X.

10.1101/518415 — bioinformatics — Posted on 2019-03-24

898 A generic multivariate framework for the integration of microbiome longitudinal studies with other data types

Bodein, A.; Chapleur, O.; Droit, A.; Le Cao, K.-A.

10.1101/585802 — bioinformatics — Posted on 2019-03-24

899 Morphological variation in Blommersia pelvic shape coincides with muscular architecture and parallels genus phylogenetic evolution

Santos-Santos, J. H.; Guinovart-Castan, M.; Vieites, D.

10.1101/586248 — evolutionary biology — Posted on 2019-03-24

900 Prediction of inter-residue contacts with DeepMetaPSICOV in CASP13

Kandathil, S. M.; Greener, J. G.; Jones, D. T.

10.1101/586800 — bioinformatics — Posted on 2019-03-24

901 Computational and experimental insights into the chemosensory navigation of Aedes aegypti mosquito larvae

Lutz, E. K.; Grewal, T. S.; Riffell, J. A.

10.1101/585075 — animal behavior and cognition — Posted on 2019-03-24

902 On Transformative Adaptive Activation Functions in Neural Networks for Gene Expression Inference

Kunc, V.; Klema, J.

10.1101/587287 — bioinformatics — Posted on 2019-03-24

903 COMICS: A pipeline for the composite identification of selection across multiple genomic scans using Invariant Coordinate Selection in R

Nelson, J. T.; Cornejo, O. E.

10.1101/587469 — bioinformatics — Posted on 2019-03-24

904 MethylCal: Bayesian calibration of methylation levels

Ochoa, E.; Zuber, V.; Fernandez-Jimenez, N.; Bilbao, J. R.; Clark, G. R.; Maher, E. R.; Bottolo, L.

10.1101/587519 — bioinformatics — Posted on 2019-03-24

905 Single-cell interactomes of the human brain reveal cell-type specific convergence of brain disorders

Mohammadi, S.; Davila-Velderrain, J.; Kellis, M.

10.1101/586859 — systems biology — Posted on 2019-03-24

906 Germline features associated with immune infiltration in solid tumors

Shahamatdar, S.; He, M. X.; Reyna, M.; Gusev, A.; AlDubayan, S. H.; Van Allen, E. M.; Ramachandran, S.

10.1101/586081 — genetics — Posted on 2019-03-24

907 Quantitation of cis-translational control by general mRNA sequence features in five eukaryotes

Li, J. J.; Chew, G.-L.; Biggin, M. D.

10.1101/587584 — genomics — Posted on 2019-03-24

908 Affordable Remote Monitoring of Plant Growth and Facilities using Raspberry Pi Computers

Grindstaff, B.; Mabry, M. E.; Blischak, P. D.; Quinn, M.; Pires, J. C.

10.1101/586776 — bioinformatics — Posted on 2019-03-24

909 Causal Network Inference from Gene Transcriptional Time Series Response to Glucocorticoids

Lu, J.; Dumitrascu, B.; McDowell, I. C.; Jo, B.; Barrera, A.; Hong, L. K.; Leichter, S.; Reddy, T. E.; Engelhardt, B. E.

10.1101/587170 — bioinformatics — Posted on 2019-03-24

910 Bipartite anchoring of SCREAM enforces stomatal initiation by coupling MAP Kinases to SPEECHLESS

Putarjunan, A.; Ruble, J.; Srivastava, A.; Zhao, C.; Rychel, A. L.; Hofstetter, A. K.; Tang, X.; Zhu, J.-K.; Tama, F.; Zheng, N.; Torii, K. U.

10.1101/587154 — plant biology — Posted on 2019-03-24

911 Linear Double-stranded DNAs as Innovative Biological Parts to Implement Genetic Circuits in Mammalian Cells

Li, S.; Su, W.; Zhang, C.

10.1101/266056 — synthetic biology — Posted on 2019-03-24

912 Integrated Field’s metal microelectrodes based microfluidic impedance cytometry for cell-in-droplet quantification

Panwar, J.; Roy, R.

10.1101/278069 — bioengineering — Posted on 2019-03-24

913 Spatial structure governs the mode of tumour evolution

Noble, R.; Burri, D.; Kather, J. N.; Beerenwinkel, N.

10.1101/586735 — cancer biology — Posted on 2019-03-23

914 DNA-scaffolded biomaterials enable modular and tunable control of cell-based cancer immunotherapies

Huang, X.; Williams, J. Z.; Chang, R.; Li, Z.; Gai, E.; Patterson, D. M.; Yu, W.; Lim, W. A.; Desai, T. A.

10.1101/587105 — bioengineering — Posted on 2019-03-23

915 3D microenvironment stiffness regulates tumor spheroid growth and mechanics via p21 and ROCK

Taubenberger, A. V.; Girardo, S.; Traber, N.; Fischer-Friedrich, E.; Krater, M.; Wagner, K.; Kurth, T.; Richter, I.; Haller, B.; Binner, M.; Hahn, D.; Freudenberg, U.; Werner, C.; Guck, J.

10.1101/586784 — bioengineering — Posted on 2019-03-23

916 eIF5B gates the transition from translation initiation to elongation

Wang, J.; Johnson, A. G.; Lapointe, C. P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A. N.; Puglisi, J. D.

10.1101/587022 — biochemistry — Posted on 2019-03-23

917 EvolvingSTEM: A microbial evolution-in-action curriculum that enhances learning of evolutionary biology and biotechnology

Cooper, V. S.; Warren, T. M.; Matela, A. M.; Handwork, M.; Scarponi, S.

10.1101/514513 — evolutionary biology — Posted on 2019-03-23

918 Direct and transgenerational effects of an experimental heat wave on early life stages in a freshwater snail

Leicht, K.; Seppala, O.

10.1101/449777 — ecology — Posted on 2019-03-23

919 Lipid membranes trigger misfolding and self-assembly of amyloid β 42 protein into aggregates

Banerjee, S.; Hashemi, M.; Zagorski, K.; Lyubchenko, Y.

10.1101/587493 — neuroscience — Posted on 2019-03-23

920 Human DNA-PK activates a STING-independent DNA sensing pathway

Burleigh, K.; Maltbaek, J.; Cambier, S.; Green, R.; Gale, M.; James, R. C.; Stetson, D. B.

10.1101/587501 — immunology — Posted on 2019-03-23

921 IMPACT OF GENOME ARCHITECTURE UPON THE FUNCTIONAL ACTIVATION AND REPRESSION OF Hox REGULATORY LANDSCAPES

Rodriguez-Carballo, E.; Lopez-Delisle, L.; Yakushiji-Kaminatsui, N.; Ullate-Agote, A.; Duboule, D.

10.1101/587303 — developmental biology — Posted on 2019-03-23

922 Constitutive expression of a fluorescent protein reports the size of live human cells

Berenson, D. F.; Zatulovskiy, E.; Xie, S.; Skotheim, J. M.

10.1101/587162 — cell biology — Posted on 2019-03-23

923 Class A GPCRs use the membrane potential to increase their sensitivity and selectivity

Shalaeva, D.; Cherepanov, D.; Galperin, M.; Vriend, G.; Mulkidjanian, A.

10.1101/587576 — biophysics — Posted on 2019-03-23

924 Intelligent Design of 14-3-3 Docking Proteins Utilizing Synthetic Evolution Artificial Intelligence (SYN-AI)

Davis, L. K.

10.1101/587204 — synthetic biology — Posted on 2019-03-23

925 CDC6 regulates both G2/M transition and metaphase-to-anaphase transition during the first meiosis of mouse oocytes

Yi, Z.; Meng, T.; Ma, X.; Li, J.; Zhang, C.; Ouyang, Y.; Heide, S.; Qiao, J.; Sun, Q.-Y.; Qian, W.

10.1101/587238 — developmental biology — Posted on 2019-03-23

926 High-throughput Multimodal Automated Phenotyping (MAP) with Application to PheWAS

Liao, K. P.; Sun, J.; Cai, T. A.; Link, N.; Hong, C.; Huang, J.; Huffman, J. E.; Gronsbell, J.; Zhang, Y.; Ho, Y.-L.; Castro, V.; Gainer, V.; Murphy, S. N.; O'Donnell, C. J.; Gaziano, M. J.; Cho, K.; Szolovits, P.; Kohane, I. S.; Yu, S.; Cai, T.; VA Million Veteran Program,

10.1101/587436 — bioinformatics — Posted on 2019-03-23

927 Honey bee (Apis mellifera) larval pheromones regulate gene expression related to foraging task specialization

Ma, R.; Rangel, J.; Grozinger, C. M.

10.1101/587113 — genomics — Posted on 2019-03-23

928 The polyploid genome of the mitotic parthenogenetic root knot nematode Meloidogyne enterolobii

Koutsovoulos, G. D.; Poullet, M.; El Ashry, A.; Kozlowski, D. K.; Sallet, E.; Da Rocha, M.; Martin-Jimenez, C.; Perfus-Barbeoch, L.; Frey, J.-E.; Ahrens, C.; Kiewnick, S.; Danchin, E. G.

10.1101/586818 — genomics — Posted on 2019-03-23

929 Single-shot autofocus microscopy using deep learning

Pinkard, H.; Phillips, Z.; Babakhani, A.; Fletcher, D. A.; Waller, L.

10.1101/587485 — bioengineering — Posted on 2019-03-23

930 pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive

Choudhary, S.

10.1101/578500 — bioinformatics — Posted on 2019-03-23

931 p63 cooperates with CTCF to modulate chromatin architecture in skin keratinocytes

Qu, J.; Yi, G.; Zhou, H.

10.1101/525667 — genomics — Posted on 2019-03-23

932 Modulation of kinesin’s load-bearing capacity by force geometry and the microtubule track

Pyrpassopoulos, S.; Shuman, H.; Ostap, E. M.

10.1101/587089 — biophysics — Posted on 2019-03-23

933 Coolpup.py - a versatile tool to perform pile-up analysis of Hi-C data

Flyamer, I. M.; Illingworth, R. S.; Bickmore, W. A.

10.1101/586537 — bioinformatics — Posted on 2019-03-23

934 Direct visualization of single nuclear pore complex proteins using genetically-encoded probes for DNA-PAINT

Schlichthaerle, T.; Strauss, M. T.; Schueder, F.; Auer, A.; Nijmeijer, B.; Kueblbeck, M.; Jimenez Sabinina, V.; Thevatasan, J. V.; Ries, J.; Ellenberg, J.; Jungmann, R.

10.1101/579961 — cell biology — Posted on 2019-03-23

935 RB1 deletion in RB-pathway disrupted cells results in DNA damage and cancer progression.

Marshall, A.; Roes, M.; Passos, D. T.; DeWeerd, M.; Chaikovsky, A.; Sage, J.; Howlett, C.; Dick, F. A.

10.1101/564567 — cancer biology — Posted on 2019-03-23

936 Statistically consistent divide-and-conquer pipelines for phylogeny estimation using NJMerge

Molloy, E. K.; Warnow, T.

10.1101/469130 — evolutionary biology — Posted on 2019-03-23

937 Strong Patterns of Intraspecific Variation and Local Adaptation in Great Basin Plants Revealed Through a Review of 75 Years of Experiments

Baughman, O. W.; Agneray, A. C.; Forister, M. L.; Kilkenny, F. F.; Espeland, E. K.; Fiegener, R.; Horning, M. E.; Johnson, R. C.; Kaye, T. N.; Ott, J. E.; St Clair, J. B.; Leger, E. A.

10.1101/506089 — ecology — Posted on 2019-03-23

938 The inherent multidimensionality of temporal variability: How common and rare species shape stability patterns

Arnoldi, J.-F.; Loreau, M.; Haegeman, B.

10.1101/431296 — ecology — Posted on 2019-03-23

939 Using a large-scale biodiversity monitoring dataset to test the effectiveness of protected areas at conserving North-American breeding birds

Cazalis, V.; Belghali, S.; Rodrigues, A. S. L.

10.1101/433037 — ecology — Posted on 2019-03-23

940 Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells

Earle, A. J.; Kirby, T. J.; Fedorchak, G. R.; Isermann, P.; Patel, J.; Iruvanti, S.; Moore, S. A.; Bonne, G.; Wallrath, L. L.; Lammerding, J.

10.1101/364778 — cell biology — Posted on 2019-03-23

941 A model of the entrance pupil of the human eye

Aguirre, G. K.

10.1101/325548 — neuroscience — Posted on 2019-03-23

942 Effective clustering for Single Cell Sequencing cancer data

Ciccolella, S.; Patterson, M.; Bonizzoni, P.; Della Vedova, G.

10.1101/586545 — cancer biology — Posted on 2019-03-23

943 IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress

Grey, M. J.; Cloots, E.; Simpson, M. S.; LeDuc, N.; Serebrenik, Y.; De Luca, H.; De Sutter, D.; Luong, P.; Thiagarajah, J. R.; Paton, A. W.; Paton, J. C.; Seeliger, M.; Eyckerman, S.; Janssens, S.; Lencer, W. I.

10.1101/586305 — cell biology — Posted on 2019-03-23

944 How signals of calcium ions initiate the beats of cilia and flagella

Tuszynski, J. A.; Sataric, M.; Nemes, T.; Sekulic, D. L.

10.1101/585034 — biophysics — Posted on 2019-03-23

945 3D association of ER, PR and Her2 at protein levels to aid sub-grouping of breast cancer patients in routine clinical practice

Lv, J.; Yu, G.; Li, L.; Zhang, Y.; Zhang, W.; Lv, Y.; Zhang, J.; Tang, F.

10.1101/584599 — pathology — Posted on 2019-03-23

946 Control of the Endo-Lysosome Homeostasis by the Paracaspase MALT1 regulates Glioma Cell Survival

Jacobs, K. A.; Andre-Gregoire, G.; Maghe, C.; Li, Y.; Thys, A.; Harford-Wright, E.; Trillet, K.; Douanne, T.; Frenel, J.-S.; Bidere, N.; Gavard, J.

10.1101/582221 — cell biology — Posted on 2019-03-23

947 tbiExtractor: A framework for Extracting Traumatic Brain Injury Common Data Elements from Radiology Reports

Mahan, M.; Rafter, D.; Casey, H.; Engelking, M.; Abdallah, T.; Truwit, C.; Oswood, M.; Samadani, U.

10.1101/585331 — bioinformatics — Posted on 2019-03-23

948 A stochastic spatial model for heterogeneity in cancergrowth

Queiroga, A. S.; de Morais, M. C. C.; Tortelli, T. C.; Chammas, R.; Ramos, A. F.

10.1101/584573 — systems biology — Posted on 2019-03-23

949 Non-enzymatically oxidized arachidonic acid regulates mouse spermatogenic cell T-type Ca2+ currents

Bondarenko, O.; Corzo, G.; Santana, F. L.; del Rio-Portilla, F.; Darszon, A.; Lopez-Gonzalez, I.

10.1101/586297 — physiology — Posted on 2019-03-23

950 Integrin-dependent YAP signaling requires LAMTOR1 mediated delivery of Src to the plasma membrane

Bouvard, D.; Block, M.; Brunner, M.; Ziegelmeyer, T.; Lallemand, D.; Pezet, M.; Chevalier, G.; Ronde, P.; Wehrle-Haller, B. M.

10.1101/585349 — cell biology — Posted on 2019-03-23

951 N-chlorination mediates protective and immunomodulatory effects of oxidized human plasma proteins

Ulfig, A.; Schulz, A. V.; Müller, A.; Lupilov, N.; Leichert, L. I.

10.1101/584961 — biochemistry — Posted on 2019-03-23

952 Genetic analysis reveals novel roles for mei-MCM proteins during meiotic recombination in Drosophila

Hatkevich, T.; Hartmann, M. A.; Kohl, K. P.; Sekelsky, J.

10.1101/467134 — genetics — Posted on 2019-03-23

953 Handling and Adequacy of Iodine at Household Level: Community Based Cross-sectional Survey in Dega Damot District, West Gojjam Zone, Amhara Regional State, Ethiopia

Bitew, A. A.; Linigerew, W. M.; Mengistu, A. A.; Tessema, A. L.

10.1101/586677 — epidemiology — Posted on 2019-03-23

954 Modular tissue-specific regulation of doublesex underpins sexually dimorphic development in Drosophila

Rice, G.; Barmina, O.; Luecke, D.; Hu, K.; Arbeitman, M.; Kopp, A.

10.1101/585158 — developmental biology — Posted on 2019-03-23

955 Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition

Wasnick, R. M.; Korfei, M.; Piskulak, K.; Henneke, I.; Wilhelm, J.; Mahavadi, P.; von der Beck, D.; Koch, M.; Shalashova, I.; Klymenko, O.; Fink, L.; Witt, H.; Hackstein, H.; El Agha, E.; Bellusci, S.; Klepetko, W.; Koenigshoff, M.; Eickelberg, O.; Braun, T.; Seeger, W.; Ruppert, C.; Guenther, A.

10.1101/580498 — cell biology — Posted on 2019-03-23

956 Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras

Xu, R.; Brawner, A.; Li, S.; Liu, J.; Kim, H.; Xue, H.; Pang, Z.; Kim, W.-Y.; Hart, R.; Liu, Y.; Jiang, P.

10.1101/462739 — neuroscience — Posted on 2019-03-23

957 Accelerated brain ageing and disability in multiple sclerosis

Cole, J. H.; Raffel, J.; Friede, T.; Eshaghi, A.; Brownlee, W.; Chard, D.; De Stefano, N.; Enzinger, C.; Pirpamer, L.; Filippi, M.; Gasperini, C.; Rocca, M. A.; Rovira, A.; Ruggieri, S.; Sastre-Garriga, J.; Stromillo, M. L.; Uitdehaag, B.; Vrenken, H.; Barkhof, F.; Nicholas, R.; Ciccarelli, O.

10.1101/584888 — neuroscience — Posted on 2019-03-23

958 Serial femtosecond X-ray diffraction of HIV-1 Gag MA-IP6 microcrystals at ambient temperature

Ciftci, H. I.; Sierra, R. G.; Yoon, C. H.; Su, Z.; Tateishi, H.; Koga, R.; Kotaro, K.; Yumoto, F.; Senda, T.; Liang, M.; Wakatsuki, S.; Otsuka, M.; Fujita, M.; Demirci, H.

10.1101/561100 — biophysics — Posted on 2019-03-23

959 Brucella periplasmic protein EipB is a molecular determinant of cell envelope integrity and virulence

Herrou, J.; Willett, J.; Fiebig, A.; Czyz, D.; Cheng, J.; Ultee, E.; Briegel, A.; Bigelow, L.; Babnigg, G.; Kim, Y.; Crosson, S.

10.1101/551135 — microbiology — Posted on 2019-03-23

960 Characterization of coral-associated microbial aggregates (CAMAs) within tissues of the coral Acropora hyacinthus

Wada, N.; Ishimochi, M.; Matsui, T.; Pollock, F. J.; Tang, S.-L.; Ainsworth, T. D.; Willis, B. L.; Mano, N.; Bourne, D. G.

10.1101/576488 — microbiology — Posted on 2019-03-23

961 Pluripotent Stem Cell-derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins

Kim, H.; Xu, R.; Ragunathan, P.; Dunaevsky, A.; Liu, Y.; Dreyfus, C.; Jiang, P.

10.1101/460907 — developmental biology — Posted on 2019-03-23

962 Cellular correlates of cortical thinning throughout the lifespan

Vidal-Pineiro, D.; Parker, N.; Shin, J.; French, L.; Jackowski, A. P.; Mowinckel, A. M.; Patel, Y.; Pausova, Z.; Salum, G.; Sorensen, O.; Walhovd, K. B.; Paus, T.; Fjell, A. M.; the AIBL,

10.1101/585786 — neuroscience — Posted on 2019-03-23

963 SPDI: Data Model for Variants and Applications at NCBI

Holmes, J. B.; Moyer, E.; Phan, L.; Maglott, D.; Kattman, B. L.

10.1101/537449 — genomics — Posted on 2019-03-23

964 Genomic Prediction of Complex Disease Risk

Lello, L.; Raben, T. G.; Yong, S. Y.; Tellier, L. C.; Hsu, S. D. H.

10.1101/506600 — genomics — Posted on 2019-03-23

965 Balancing selection shapes the Intracellular Pathogen Response in natural Caenorhabditis elegans populations

van Sluijs, L.; Bosman, K. J.; Pankok, F.; Blokhina, T.; Riksen, J. A. G.; Snoek, B.; Pijlman, G. P.; Kammenga, J. E.; Sterken, M. G.

10.1101/579151 — genetics — Posted on 2019-03-23

966 Holobiont Evolution: Model with Vertical vs. Horizontal Microbiome Transmission

Roughgarden, J.

10.1101/465310 — evolutionary biology — Posted on 2019-03-23

967 Adaptation and latitudinal gradients in species interactions: nest predation in birds

Freeman, B.; Scholer, M.; Boehm, M.; Heavyside, J.; Schluter, D.

10.1101/552380 — evolutionary biology — Posted on 2019-03-23

968 Strong Patterns of Intraspecific Variation and Local Adaptation in Great Basin Plants Revealed Through a Review of 75 Years of Experiments

Baughman, O. W.; Agneray, A. C.; Forister, M. L.; Kilkenny, F. F.; Espeland, E. K.; Fiegener, R.; Horning, M. E.; Johnson, R. C.; Kaye, T. N.; Ott, J. E.; St Clair, J. B.; Leger, E. A.

10.1101/506089 — ecology — Posted on 2019-03-23

969 Open channel droplet-based microfluidics

Berry, S. B.; Lee, J. J.; Berthier, J.; Berthier, E.; Theberge, A.

10.1101/436675 — bioengineering — Posted on 2019-03-23

970 Coupled Reaction Networks for Noise Suppression

Xiao, F.; Fang, M.; Yan, J.; Doyle, J. C.

10.1101/440453 — systems biology — Posted on 2019-03-23

971 Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse

Cross, S. H.; Mckie, L.; Keighren, M.; West, K.; Thaung, C.; Davey, T.; Sanchez-Pulido, L.; Soares, D.; Jackson, I. J.

10.1101/513846 — molecular biology — Posted on 2019-03-23

972 Assays for monitoring Toxoplasma gondii infectivity in the laboratory mouse

Wang, Q.; David Sibley, L.

10.1101/584474 — microbiology — Posted on 2019-03-23

973 Desiccation-induced changes in recombination rate and crossover interference in Drosophila melanogaster: evidence for fitness-dependent plasticity

Aggarwal, D. D.; Rybnikov, S. R.; Cohen, I.; Frenkel, Z.; Rashkovetsky, E.; Michalak, P.; Korol, A. B.

10.1101/382259 — genetics — Posted on 2019-03-23

974 Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four healthcare systems

Zheutlin, A. B.; Dennis, J.; Karlsson Linner, R.; Moscati, A.; Restrepo, N.; Straub, P.; Ruderfer, D.; Castro, V. M.; Chen, C.-Y.; Ge, T.; Huckins, L. M.; Charney, A.; Kirchner, H. L.; Stahl, E. A.; Chabris, C. F.; Davis, L. K.; Smoller, J. W.

10.1101/421164 — genetics — Posted on 2019-03-23

975 Sex allocation conflict and sexual selection throughout the lifespan of eusocial colonies

Avila, P.; Fromhage, L.; Lehmann, L.

10.1101/454512 — evolutionary biology — Posted on 2019-03-23

976 Using a large-scale biodiversity monitoring dataset to test the effectiveness of protected areas at conserving North-American breeding birds

Cazalis, V.; Belghali, S.; Rodrigues, A. S. L.

10.1101/433037 — ecology — Posted on 2019-03-23

977 Musashi binding elements in Zika and related Flavivirus 3’UTRs: A comparative study in silico

de Bernardi Schneider, A.; Wolfinger, M. T.

10.1101/407833 — bioinformatics — Posted on 2019-03-23

978 A model of the entrance pupil of the human eye

Aguirre, G. K.

10.1101/325548 — neuroscience — Posted on 2019-03-23

979 Using X-ray microtomography to uncover the visual world of ancient and historical insects

Taylor, G. J.; Hall, S. A.; Gren, J. A.; Baird, E.

10.1101/290841 — evolutionary biology — Posted on 2019-03-23

980 Persistence of cooperation in diffusive public goods games

Gerlee, P.; Altrock, P. M.

10.1101/352492 — ecology — Posted on 2019-03-23

981 Learning mutational graphs of individual tumour evolution from single-cell and multi-region sequencing data

Ramazzotti, D.; Graudenzi, A.; De Sano, L.; Antoniotti, M.; Caravagna, G.

10.1101/132183 — bioinformatics — Posted on 2019-03-23

982 MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions

Piccolo, F.; Liu, Z.; Dong, P.; Hsu, C.-L.; Stoyanova, E. I.; Rao, A.; Tjian, R.; Heintz, N.

10.1101/586867 — molecular biology — Posted on 2019-03-23

983 Modulation of kinesin’s load-bearing capacity by force geometry and the microtubule track

Pyrpassopoulos, S.; Shuman, H.; Ostap, E. M.

10.1101/587089 — biophysics — Posted on 2019-03-23

984 A newly defined cullin-RING ubiquitin ligase promotes thermotolerance as part of the Intracellular Pathogen Response in C. elegans

Panek, J.; Reddy, K. C.; Luallen, R. J.; Fulzele, A.; Bennett, E. J.; Troemel, E. R.

10.1101/586834 — biochemistry — Posted on 2019-03-23

985 Nanodiamonds enable adaptive-optics enhanced, super-resolution, two-photon excitation microscopy

Patton, B. R.; Johnstone, G. E.; Cairns, G. S.

10.1101/586743 — bioengineering — Posted on 2019-03-22

986 Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature

Carneiro, C. F. D.; Queiroz, V. G. S.; Moulin, T. C.; Carvalho, C. A. M.; Haas, C. B.; Rayee, D.; Henshall, D. E.; De-Souza, E. A.; Espinelli, F.; Boos, F. Z.; Guercio, G. D.; Costa, I. R.; Hajdu, K. L.; Modrak, M.; Tan, P. B.; Burgess, S. J.; Guerra, S. F. S.; Bortoluzzi, V. T.; Amaral, O. B.

10.1101/581892 — scientific communication and education — Posted on 2019-03-22

987 Anchoring of actin to the plasma membrane enables tension production in the fission yeast cytokinetic ring

Wang, S.; O'Shaughnessy, B.

10.1101/586792 — cell biology — Posted on 2019-03-22

988 The ability of single genes vs full genomes to resolve time and space in outbreak analysis

Dudas, G.; Bedford, T.

10.1101/582957 — epidemiology — Posted on 2019-03-22

989 Lifetime changes in CD4 count, viral load suppression and adherence among adolescents living with HIV in urban Peru

Rodriguez, C.; Kolevic, L.; Ramos, A.; Wong, M.; Munoz, M.; Patel, K.; Franke, M. F.

10.1101/580084 — epidemiology — Posted on 2019-03-22

990 Patterns and predictors of Staphylococcus aureus carriage during the first year of life; a longitudinal study

Regev-Yochay, G.; Reiss-Mandel, A.; Rubin, C.; Maayan-Metzger, A.; Novikov, I.; Jaber, H.; Dolitzky, M.; Freedman, L.; Rahav, G.

10.1101/586032 — epidemiology — Posted on 2019-03-22

991 Multiple-serotype models of dengue virus transmission: simulation study and perspectives for the application of inference in epidemiological surveillance

Souto-Maior, C.

10.1101/583351 — epidemiology — Posted on 2019-03-22

992 Gestational diabetes using diverse diagnostic criteria, risk factors including dietary intakes, pregnancy outcomes and postpartum glycemic status: a nested case-control study in Ghana

Agbozo, F.; Abubakari, A.; Zotor, F.; Jahn, A.

10.1101/582239 — epidemiology — Posted on 2019-03-22

993 A multidimensional functional fitness score is a stronger predictor of type 2 diabetes than obesity parameters in cross sectional data.

Patil, P.; Lalwani, P.; Vidwans, H. B.; Kulkarni, S. A.; Bais, D.; Diwekar-Joshi, M. M.; Rasal, M.; Bhasme, N.; Naik, M.; Batwal, S.; Watve, M.

10.1101/580860 — epidemiology — Posted on 2019-03-22

994 Landscape epidemiology of ash dieback

Grosdidier, M.; Scordia, T.; Ioos, R.; Marcais, B.

10.1101/582080 — epidemiology — Posted on 2019-03-22

995 Understanding the population structure of the GHQ-12: evidence for multidimensionality using Bayesian and Exploratory Structural Equation Modelling from a large-scale UK population survey.

Griffith, G.; Jones, K.

10.1101/584169 — epidemiology — Posted on 2019-03-22

996 The genome of the blind soil-dwelling and ancestrally wingless dipluran Campodea augens, a key reference hexapod for studying the emergence of insect innovations

Manni, M.; Simao, F. A.; Robertson, H. M.; Gabaglio, M. A.; Waterhouse, R. M.; Misof, B.; Niehuis, O.; Szucsich, N.; Zdobnov, E. M.

10.1101/585695 — genomics — Posted on 2019-03-22

997 TM3’seq: a tagmentation-mediated 3’ sequencing approach for improving scalability of RNA-seq experiments

Pallares, L. F.; Picard, S.; Ayroles, J. F.

10.1101/585810 — genomics — Posted on 2019-03-22

998 Population genomics data supports introgression between Western Iberian Squalius freshwater fish species from different drainages

Mendes, S.; Coelho, M. M.; Sousa, V. C.

10.1101/585687 — evolutionary biology — Posted on 2019-03-22

999 OMGS: Optical Map-based Genome Scaffolding

Pan, W.; Jiang, T.; Lonardi, S.

10.1101/585794 — bioinformatics — Posted on 2019-03-22

1000 Effect of motor learning on prosthetic finger controlwith an intuitive myoelectric decoder

Krasoulis, A.; Vijayakumar, S.; Nazarpour, K.

10.1101/585703 — bioengineering — Posted on 2019-03-22

1001 Measures of states of consciousness during attentional and cognitive load

Sevenius Nilsen, A.; Juel, B. E.; Storm, J. F.

10.1101/586149 — neuroscience — Posted on 2019-03-22

1002 Error, noise and bias in de novo transcriptome assemblies

Freedman, A. H.; Clamp, M.; Sackton, T. B.

10.1101/585745 — bioinformatics — Posted on 2019-03-22

1003 Coolpup.py - a versatile tool to perform pile-up analysis of Hi-C data

Flyamer, I. M.; Illingworth, R. S.; Bickmore, W. A.

10.1101/586537 — bioinformatics — Posted on 2019-03-22

1004 Cellular correlates of cortical thinning throughout the lifespan

Vidal-Pineiro, D.; Parker, N.; Shin, J.; French, L.; Jackowski, A. P.; Mowinckel, A. M.; Patel, Y.; Pausova, Z.; Salum, G.; Sorensen, O.; Walhovd, K. B.; Paus, T.; Fjell, A. M.; the Australian Imaging Biomarkers & Lifestyle flag,

10.1101/585786 — neuroscience — Posted on 2019-03-22

1005 Enhanced 4Pi single-molecule localization microscopy with coherent pupil based localization and light sheet illumination

Liu, S.; Huang, F.

10.1101/586404 — biophysics — Posted on 2019-03-22

1006 Dietary polyunsaturated fatty acid supply improves Daphnia performance during vertical migration

Isanta Navarro, J.; Fromherz, M.; Dietz, M.; Zeis, B.; Schwarzenberger, A.; Martin-Creuzburg, D.

10.1101/586156 — physiology — Posted on 2019-03-22

1007 Whole-genome and RNA sequencing reveal variation and transcriptomic coordination in the developing human prefrontal cortex

Werling, D.; Pochareddy, S.; Choi, J.; An, J. Y.; Sheppard, B.; Peng, M.; Li, Z.; Dastmalchi, C.; Santperebaro, G.; Sousa, A.; Tebbenkamp, A.; Kaur, N.; Gulden, F.; Breen, M.; Liang, L.; Gilson, M.; Zhao, X.; Dong, S.; Klei, L.; Cicek, A. E.; Buxbaum, J.; Adle-Biassette, H.; Thomas, J.-L.; Aldinger, K. A.; O'Day, D. R.; Glass, I.; Zaitlen, N.; Talkowski, M.; Roeder, K.; State, M. W.; Devlin, B.; Sanders, S.; Sestan, N.

10.1101/585430 — neuroscience — Posted on 2019-03-22

1008 Cryo-EM Map of the CFA/I Pilus Rod

Zheng, W.; Andersson, M.; Mortezaei, N.; Bullitt, E.; Egelman, E. H.

10.1101/586412 — molecular biology — Posted on 2019-03-22

1009 The NEDD8 cycle controlled by NEDP1 upon DNA damage is a regulatory module of the HSP70 ATPase activity

Bailly, A.; Perrin, A.; Serrano-Macia, M.; Maghames, C.; Leidecker, O.; Trauchessec, H.; Martinez-Chantar, M.; Gartner, A.; Xirodimas, D.

10.1101/583864 — molecular biology — Posted on 2019-03-22

1010 Circular RNA profiling in the oocyte and cumulus cells reveals that circARMC4 is essential for porcine oocyte maturation

Cao, Z.; Gao, D.; Xu, T.; Zhang, L.; Tong, X.; Zhang, D.; Wang, Y.; Ning, W.; Qi, X.; Ma, Y.; Ji, K.; Yu, T.; Li, Y.; Zhang, Y.

10.1101/586024 — developmental biology — Posted on 2019-03-22

1011 FSHR-1/GPCR activates the mitochondrial unfolded protein response in Caenorhabditis elegans

Kim, S.; Sieburth, D.

10.1101/586883 — cell biology — Posted on 2019-03-22

1012 Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase

Cain, R.; Salimaraj, R.; Punekar, A. S.; Bellini, D.; Fishwisk, C. W. G.; Czapleski, L.; Scott, D. J.; Harris, G.; Dowson, C. G.; Lloyd, A. J.; Roper, D. I.

10.1101/586255 — biochemistry — Posted on 2019-03-22

1013 Neurodegeneration caused by LRRK2-G2019S requires Rab10 in select dopaminergic neurons

Petridi, S.; Middleton, C. A.; Fellgett, A.; Covill, L.; Stewart, A.; Munns, J.; Kohrs, F. E.; Hiesinger, P. R.; Wilson, L.; Chawla, S.; Elliott, C.

10.1101/586073 — neuroscience — Posted on 2019-03-22

1014 The shift to life on land selected for planning

Mugan, U.; MacIver, M. A.

10.1101/585760 — neuroscience — Posted on 2019-03-22

1015 The genomic diversification of clonally propagated grapevines

Vondras, A.; Minio, A.; Blanco-Ulate, B.; Figueroa, R.; Penn, M.; Zhou, Y.; Seymour, D.; Zhou, Y.; Liang, D.; Espinoza, L.; Anderson, M.; Walker, M. A.; Gaut, B.; Cantu, D.

10.1101/585869 — genomics — Posted on 2019-03-22

1016 Transcriptomics supports that pleuropodia of insect embryos function in degradation of the serosal cuticle to enable hatching

Konopova, B.; Buchberger, E.; Crisp, A.

10.1101/584029 — developmental biology — Posted on 2019-03-22

1017 Grant Reviewer Perceptions of Panel Discussion in Face-to-Face and Virtual Formats: Lessons from Team Science?

Gallo, S. A.; Schmaling, K.; Thompson, L. A.; Glisson, S.

10.1101/586685 — scientific communication and education — Posted on 2019-03-22

1018 Deliver on Your Own: Disrespectful Maternity Care in rural Kenya

Lusambili, A. M.; Naanyu, V. N.; Wade, T. J.; Mossman, L.; Pell, R.; Mulama, K.; Nyaga, L.; Obure, J.; Mantel, M.; Ngetich, A.; Temmerman, M.

10.1101/586693 — scientific communication and education — Posted on 2019-03-22

1019 Disparate effects of antibiotic-induced microbiome change and enhanced fitness in Daphnia magna

Motiei, A.; Brindefalk, B.; Ogonowski, M.; El-Shehawy, R.; Pastuszek, P.; Ek, K.; Liewenborg, B.; Udekwu, K.; Gorokhova, E.

10.1101/586669 — pharmacology and toxicology — Posted on 2019-03-22

1020 A salt-induced kinase (SIK) is required for the metabolic regulation of sleep

Grubbs, J. J.; Lopes, L. E.; van der Linden, A. M.; Raizen, D. M.

10.1101/586701 — neuroscience — Posted on 2019-03-22

1021 ERK1/2 signalling dynamics promote neural differentiation by regulating the polycomb repressive complex

Semprich, C. I.; Metzis, V.; Patel, H.; Briscoe, J.; Storey, K. G.

10.1101/586719 — developmental biology — Posted on 2019-03-22

1022 Genetic admixture patterns in Argentinian Patagonia

Parolin, M. L.; Toscanini, U. F.; Velazquez, I. F.; Llull, C.; Berardi, G. L.; Holley, A.; Tamburrini, C.; Avena, S.; Carnese, F. R.; Lanata, J. L.; Sanchez Carnero, N.; Arce, L. F.; Basso, N. G.; Pereira, R.; Gusmao, L.

10.1101/586610 — genetics — Posted on 2019-03-22

1023 Genetic and antigenic variation of foot-and-mouth disease virus during persistent infection in naturally infected cattle and Asian buffalo in India

Biswal, J. K.; Ranjan, R.; Subramaniam, S.; Mohapatra, J. K.; Patidar, S.; Sharma, M. K.; Bertram, M. R.; Brito, B.; Rodriguez, L. L.; Pattnaik, B.; Arzt, J.

10.1101/586644 — evolutionary biology — Posted on 2019-03-22

1024 Levels of knowledge and attitude on preconception care at public hospitals in Wolayita Zone, South Ethiopia

kassa, z. y.; Tenaw, Z.; Astatkie, A.; Siyoum, M.; Bekele, G.; Taye, K.; Mekonnen, S.; Kassaye, Z.

10.1101/586636 — epidemiology — Posted on 2019-03-22

1025 Numerical simulation for behind armor blunt trauma of human torso under non-penetrating ballistic impact

Tang, F.; Guo, Z.; Yuan, M.; Qian, X.; Du, Z.

10.1101/586594 — bioengineering — Posted on 2019-03-22

1026 Effects of short-term resistance training and tapering on maximal strength, peak power, throwing ball velocity, and sprint performance in handball players

Hermassi, S.; Ghaith, A.; Schwesig, R.; Shephard, R. J.; Souhaiel Chelly, M.

10.1101/586586 — developmental biology — Posted on 2019-03-22

1027 Tamoxifen Suppresses Pancreatic β-Cell Proliferation in Mice

Ahn, S.-H.; Granger, A.; Rankin, M. M.; Lam, C. J.; Cox, A. R.; Kushner, J. A.

10.1101/586602 — developmental biology — Posted on 2019-03-22

1028 Stratification and prediction of drug synergy based on target functional similarity

Yang, M.; Menden, M. P.; Jaaks, P.; Dry, J.; Garnett, M.; Saez-Rodriguez, J.

10.1101/586123 — bioinformatics — Posted on 2019-03-22

1029 A multi-omics digital research object for the genetics of sleep regulation.

Jan, M.; Gobet, N.; Diessler, S.; Franken, P.; Xenarios, I.

10.1101/586206 — bioinformatics — Posted on 2019-03-22

1030 Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation

Selewa, A.; Dohn, R.; Eckart, H.; Lozano, S.; Xie, B.; Gauchat, E.; Elorbany, R.; Rhodes, K.; Burnett, J.; Gilad, Y.; Pott, S.; Basu, A.

10.1101/585901 — genomics — Posted on 2019-03-22

1031 Selection on VPS13A linked to long-distance migratory behavior in a songbird

Toews, D. P. L.; Taylor, S. A.; Streby, H. M.; Kramer, G. R.; Lovette, I. J.

10.1101/585398 — evolutionary biology — Posted on 2019-03-22

1032 Optimal Individualized Combination Immunotherapy/Oncolytic Virotherapy Determined Through In Silico Clinical Trials Improves Late Stage Melanoma Patient Outcomes

Cassidy, T.; Craig, M.

10.1101/585711 — cancer biology — Posted on 2019-03-22

1033 Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodelling

Katris, N. J.; Amiar, S.; Berry, L.; Dass, S.; Shears, M. J.; Brunet, C.; Touquet, B.; Hakimi, M.-A.; McFadden, G. I.; Yamaryo-Botte, Y.; Botte, C. Y.

10.1101/585737 — microbiology — Posted on 2019-03-22

1034 PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

Jain, S. U.; Do, T. J.; Lund, P. J.; Rashoff, A. Q.; Cieslik, M.; Diehl, K. L.; Bajic, A.; Juretic, N.; Deshmukh, S.; Venneti, S.; Muir, T. W.; Garcia, B. A.; Jabado, N.; Lewis, P. W.

10.1101/585729 — cancer biology — Posted on 2019-03-22

1035 Characterization of genes and alleles involved in the control of flowering time in grapevine

Kamal, N.; Ochssner, I.; Schwandner, A.; Viehöver, P.; Hausmann, L.; Töpfer, R.; Weisshaar, B.; Holtgräwe, D. L.

10.1101/584268 — genetics — Posted on 2019-03-22

1036 Syncrip/hnRNPQ is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation

Titlow, J.; Robertson, F.; Jarvelin, A.; Ish-Horowicz, D.; Smith, C.; Gratton, E.; Davis, I.

10.1101/585679 — neuroscience — Posted on 2019-03-22

1037 Indirect Readout of DNA Controls Filamentation and Activation of a Sequence-Specific Endonuclease

Polley, S.; Lyumkis, D.; Horton, N. C.

10.1101/585943 — biochemistry — Posted on 2019-03-22

1038 Evaluation of BMP-mediated patterning in zebrafish embryos using a growing finite difference embryo model

Li, L. M.; Wang, X. M.; Mullins, M. C.; Umulis, D. M.

10.1101/585471 — systems biology — Posted on 2019-03-22

1039 3.1A structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids

Lahiri, I.; Xu, J.; Han, B. G.; Oh, J.; Wang, D.; DiMaio, F.; Leschziner, A. E.

10.1101/585547 — molecular biology — Posted on 2019-03-22

1040 An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion

Sathyan, K. M.; McKenna, B. D.; Anderson, W.; Duarte, F. M.; Core, L. J.; Guertin, M. J.

10.1101/585927 — molecular biology — Posted on 2019-03-22

1041 The influence of image masking on object representations during rapid serial visual presentation

Robinson, A. K.; Grootswagers, T.; Carlson, T. A.

10.1101/515619 — neuroscience — Posted on 2019-03-21

1042 eNetXplorer: an R package for the quantitative exploration of elastic net families for generalized linear models

Candia, J.; Tsang, J. S.

10.1101/305870 — systems biology — Posted on 2019-03-21

1043 BrainNet: A Multi-Person Brain-to-Brain Interface for Direct Collaboration Between Brains

Jiang, L. P.; Stocco, A.; Losey, D. M.; Abernethy, J. A.; Prat, C.; Rao, R. P. N.

10.1101/425066 — bioengineering — Posted on 2019-03-21

1044 Uncovering the gene machinery of the Amazon River microbiome to degrade rainforest organic matter

Santos-Junior, C. D.; Sarmento, H.; Miranda, F. P. d.; Henrique-Silva, F.; Logares, R.

10.1101/585562 — biochemistry — Posted on 2019-03-21

1045 The GABA-Glutamate supramammillary-dorsal Dentate Gyrus pathway controls theta and gamma oscillations in the DG during paradoxical sleep

Billwiller, F.; Castillo, L.; Elseedy, H.; Ivanov, A. I.; Scapula, J.; Ghestem, A.; Carponcy, J.; Libourel, P. A.; Bras, H.; Abdelmeguid, N. E.; Krook-Magnuson, E.; Soltesz, I.; Bernard, C.; Luppi, P.-H.; Esclapez, M.

10.1101/584862 — neuroscience — Posted on 2019-03-21

1046 Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signaling

Durrant, C. S.; Ruscher, K.; Sheppard, O.; Coleman, M. P.; Özen, I.

10.1101/585489 — neuroscience — Posted on 2019-03-21

1047 An image-computable model for the stimulus selectivity of gamma oscillations

Hermes, D.; Petridou, N.; Kay, K.; Winawer, J.

10.1101/583567 — neuroscience — Posted on 2019-03-21

1048 Hierarchical temporal prediction captures motion processing from retina to higher visual cortex

Singer, Y.; Willmore, B. D.; King, A. J.; Harper, N. S.

10.1101/575464 — neuroscience — Posted on 2019-03-21

1049 The rise and fall of the new variant of Chlamydia trachomatis in Sweden: mathematical modelling study

Smid, J.; Althaus, C. L.; Low, N.; Unemo, M.; Herrmann, B.

10.1101/572107 — epidemiology — Posted on 2019-03-21

1050 A lipid-free and insulin-supplemented medium supports de novo fatty acid synthesis gene activation in melanoma cells

Wu, S.; Naar, A. M.

10.1101/479964 — cancer biology — Posted on 2019-03-21

1051 Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana - Botrytis cinerea pathosystem

Soltis, N. E.; Zhang, W.; Corwin, J. A.; Atwell, S.; Kliebenstein, D. J.

10.1101/577585 — plant biology — Posted on 2019-03-21

1052 Accelerated brain ageing and disability in multiple sclerosis

10.1101/584888 — neuroscience — Posted on 2019-03-21

1053 Developing a routine lab test for absolute quantification of Her2 in Formalin Fixed Paraffin Embedded (FFPE) breast cancer tissues using Quantitative Dot Blot (QDB) method

Yu, G.; Zhang, W.; Zhang, Y.; Lv, J.; Zhang, J.; Tang, F.

10.1101/584615 — pathology — Posted on 2019-03-21

1054 Modeling mechanisms of tremor reduction for essential tremor using symmetric biphasic DBS

Lee, S.; Asaad, W. F.; Jones, S.

10.1101/585117 — neuroscience — Posted on 2019-03-21

1055 Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients

Ravi, A.; Halstead, F.; Bamford, A.; Casey, A.; Thomson, N.; van Schaik, W.; Snelson, C.; Goulden, R.; Foster-Nyarko, E.; Savva, G.; Whitehouse, T.; PALLEN, M.; Oppenheim, B.

10.1101/582494 — microbiology — Posted on 2019-03-21

1056 Adaptation to seasonal reproduction and thermal minima-related factors drives fine-scale divergence despite gene flow in Atlantic herring populations

Fuentes-Pardo, A. P.; Bourne, C.; Singh, R.; Emond, K.; Pinkham, L.; McDermid, J. L.; Andersson, L.; Ruzzante, D. E.

10.1101/578484 — genomics — Posted on 2019-03-21

1057 Local climate and social inequality drive spatio-temporal variation in malaria risk across a complex urban landscape

Santos-Vega, M.; Lowe, R.; Anselin, L.; Desai, V.; Vaishnav, K. G.; Naik, A.; Pascual, M.

10.1101/583880 — ecology — Posted on 2019-03-21

1058 The yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response.

Svoboda, M.; Konvalinka, J.; Trempe, J.-F.; Grantz Saskova, K.

10.1101/584508 — molecular biology — Posted on 2019-03-21

1059 Gut-innervating nociceptor neurons protect against enteric infection by modulating the microbiota and Peyer’s patch microfold cells

Lai, N. Y.; Musser, M. A.; Pinho-Ribeiro, F. A.; Baral, P.; Ma, P.; Potts, D. E.; Chen, Z.; Paik, D.; Soualhi, S.; Shi, H.; Misra, A.; Goldstein, K.; Sivanathan, K. N.; Jacobson, A.; Wallrapp, A.; Lagomarsino, V.; Kuchroo, V. K.; Nowarski, R.; Starnbach, M. N.; Surana, N. K.; An, D.; Wu, C.; Huh, J. R.; Rao, M.; Chiu, I. M.

10.1101/580555 — immunology — Posted on 2019-03-21

1060 Functional diversification enabled grassy biomes to fill global climate space

Lehmann, C.; Griffith, D.; Simpson, K.; Anderson, M.; Archibald, S.; Beerling, D.; Bond, W.; Denton, E.; Edwards, E.; Forrestel, E.; Fox, D.; Georges, D.; Hoffmann, W.; Kluyver, T.; Mucina, L.; Pau, S.; Ratnam, J.; Salamin, N.; Santini, B.; Smith, M.; Spriggs, E.; Westley, R.; Still, C.; Stromberg, C.; Osborne, C.

10.1101/583625 — ecology — Posted on 2019-03-21

1061 Human Hepatocyte Nuclear Factor 4-α encodes isoforms with distinct transcriptional functions

Lambert, E.; Babeu, J.-P.; Simoneau, J.; Levesque, D.; Jolibois, E.; Scott, M. S.; Boudreau, F.; Boisvert, F.-M.

10.1101/585604 — cell biology — Posted on 2019-03-21

1062 Voice patterns in schizophrenia: A systematic review and Bayesian meta-analysis

Parola, A.; Simonsen, A.; Bliksted, V.; Fusaroli, R.

10.1101/583815 — bioinformatics — Posted on 2019-03-21

1063 Effects of healthy ageing on activation pattern within the brain during movement and motor imagery: an fMRI study.

Budhdeo, S.; Baron, J.-C.; Sharma, N.

10.1101/584813 — neuroscience — Posted on 2019-03-21

1064 Impairment but not abolishment of express saccades after unilateral- or bilateral cryogenic FEF inactivation

Dash, S.; Peel, T. R.; Lomber, S.; Corneil, B. D.

10.1101/583823 — neuroscience — Posted on 2019-03-21

1065 Levels of sdRNAs in cytoplasm and their association with ribosomes are dependent upon stress conditions but independent from snoRNA expression

Mleczko, A.; Machtel, P. J.; Walkowiak, M.; Wasilewska, A.; Bakowska-Zywicka, K.

10.1101/584367 — molecular biology — Posted on 2019-03-21

1066 Genetic architecture constrains exploitation of siderophore cooperation in Burkholderia cenocepacia

Sathe, S.; Mathew, A.; Agnoli, K.; Eberl, L.; Kummerli, R.

10.1101/583898 — evolutionary biology — Posted on 2019-03-21

1067 Combined morphological and transcriptomic analyses reveal genetic regulation underlying the species-specific bulbil outgrowth in Dioscorea alata L

Wu, Z.-G.; Jiang, W.; Tao, Z.-M.; Guo, X.-Z.; Pan, X.-J.; Yu, W.-H.

10.1101/585364 — plant biology — Posted on 2019-03-21

1068 Multiple memory tests in midlife improve prediction of mild cognitive impairment

Gustavson, D. E.; Sanderson-Cimino, M.; Elman, J. A.; Franz, C. E.; Panizzon, M. S.; Jak, A. J.; Reynolds, C. A.; Lyons, M. J.; Kremen, W. S.

10.1101/584193 — pathology — Posted on 2019-03-21

1069 Confidence reports in decision-making with multiple alternatives violate the Bayesian confidence hypothesis

Li, H.-H.; Ma, W. J.

10.1101/583963 — neuroscience — Posted on 2019-03-21

1070 Developmental Recovery of Impaired Multisensory Processing in Autism and the Cost of Switching Sensory Modality

Crosse, M. J.; Foxe, J. J.; Molholm, S.

10.1101/565333 — neuroscience — Posted on 2019-03-21

1071 Superlets: time-frequency super-resolution using wavelet sets

Moca, V. V.; Nagy-Dabacan, A.; Barzan, H.; Muresan, R. C.

10.1101/583732 — neuroscience — Posted on 2019-03-21

1072 Identification of reduced host transcriptomic signatures for tuberculosis and digital PCR-based validation and quantification

Gliddon, H. D.; Kaforou, M.; Alikian, M.; Habgood-Coote, D.; Zhou, C.; Oni, T.; Anderson, S. T.; Brent, A. J.; Crampin, A. C.; Eley, B.; Heyderman, R. S.; Kern, F.; Langford, P. R.; Ottenhoff, T. H.; French, N.; Hibberd, M. L.; Wright, V. J.; Dockrell, H. M.; Coin, L. J.; Wilkinson, R. J.; Levin, M.

10.1101/583674 — molecular biology — Posted on 2019-03-21

1073 Population history from the Neolithic to present on the Mediterranean island of Sardinia: An ancient DNA perspective

Marcus, J. H.; Posth, C.; Ringbauer, H.; Lai, L.; Skeates, R.; Sidore, C.; Beckett, J.; Furtwängler, A.; Olivieri, A.; Chiang, C.; Al-Asadi, H.; Dey, K.; Joseph, T. A.; Der Sarkissian, C.; Radzeviciute, R.; Gradoli, M. G.; Haak, W.; Reich, D.; Schlessinger, D.; Cucca, F.; Krause, J.; Novembre, J.

10.1101/583104 — genetics — Posted on 2019-03-21

1074 Exploiting the unwanted: sulphate reduction enables phosphate recovery from energy-rich sludge during anaerobic digestion.

Lippens, C.; De Vrieze, J.

10.1101/584904 — bioengineering — Posted on 2019-03-21

1075 Brain gene expression in a novel mouse model of postpartum mood disorder

Humby, T.; Davies, W.

10.1101/555870 — neuroscience — Posted on 2019-03-21

1076 Leptin reduces pathology and increases adult neurogenesis in a transgenic mouse model of Alzheimer’s disease

Calio, M. L.; Salles, G. N.; Marinho, D. S.; Mosini, A. C. F.; Massinhani, F. H.; Ko, G. M.; Porcionatto, M. A.

10.1101/567636 — neuroscience — Posted on 2019-03-21

1077 BDNF controls bidirectional endocannabinoid-plasticity at corticostriatal synapses

Gangarossa, G.; Perez, S.; Dembitskaya, Y.; Prokin, I.; Berry, H.; Venance, L.

10.1101/550947 — neuroscience — Posted on 2019-03-21

1078 A Long Timescale Stimulus History Effect in the Primary Visual Cortex

Kim, H.; Homann, J.; Tank, D. W.; Berry, M. J.

10.1101/585539 — neuroscience — Posted on 2019-03-21

1079 Relationship between cardiac cycle and the timing of actions during action execution and observation

Palser, E. R.; Glass, J.; Fotopoulou, A.; Kilner, J. M.

10.1101/585414 — neuroscience — Posted on 2019-03-21

1080 The role of feature-based attention in visual serial dependence

Fritsche, M.; de Lange, F. P.

10.1101/584789 — neuroscience — Posted on 2019-03-21

1081 The non-dominant AAA+ ring in the ClpAP protease functions as an anti-stalling motor to accelerate protein unfolding and translocation

Kotamarthi, H. C.; Sauer, R. T.; Baker, T.

10.1101/585554 — biophysics — Posted on 2019-03-21

1082 A catalog of CasX genome editing sites in common model organisms

Roberson, E. D. O.

10.1101/585521 — bioinformatics — Posted on 2019-03-21

1083 Uncovering the gene machinery of the Amazon River microbiome to degrade rainforest organic matter

Santos-Junior, C. D.; Sarmento, H.; Miranda, F. P. d.; Henrique-Silva, F.; Logares, R.

10.1101/585562 — biochemistry — Posted on 2019-03-21

1084 Gastrocnemius muscle remodeling explains functional deficits three months following Achilles tendon rupture

Hullfish, T. J.; O'Connor, K. M.; Baxter, J. R.

10.1101/585505 — physiology — Posted on 2019-03-21

1085 Neuronal network dysfunction in a human model for Kleefstra syndrome mediated by enhanced NMDAR signaling

Frega, M.; Linda, K.; Keller, J. M.; Gumus-Akay, G.; Mossink, B.; van Rhijn, J.-R.; Negwer, M.; Klein Gunnewiek, T.; Foreman, K.; Kompier, N.; Schoenmaker, C.; van den Akker, W.; Oudakker, A.; Zhou, H.; Kleefstra, T.; Schubert, D.; van Bokhoven, H.; Nadif Kasri, N.

10.1101/585596 — neuroscience — Posted on 2019-03-21

1086 Visual area V4 encodes history dependent attentional effort and single-trial perceptual detection

Ghosh, S.; Maunsell, J. H. R.

10.1101/584409 — neuroscience — Posted on 2019-03-21

1087 Srrm234, but not canonical SR and hnRNP proteins drive inclusion of Dscam exon 9 variable exons

Ustaoglu, P.; Haussmann, I.; Liao, H.; Torres-Mendez, A.; Arnold, R.; Irimia, M.; Soller, M.

10.1101/584003 — molecular biology — Posted on 2019-03-21

1088 Islet macrophages drive islet remodeling and compensatory hyperinsulinemia in the early diabetes

Chittezhath, M.; Gunaseelan, D.; Zheng, X.; Hasan, R.; Tay, V. S.; Lim, S. T.; Wang, X.; Bornstein, S.; Berggren, P.-O.; Boehm, B.; Ruedl, C.; Ali, Y.

10.1101/584953 — molecular biology — Posted on 2019-03-21

1089 Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signaling, glucose scavenging and drug detoxification and are essential for parasite survival

Tedla, B.; Sotillo, J.; Pickering, D.; Eichenberger, R.; Becker, L.; Loukas, A.; Pearson, M. S.

10.1101/583658 — molecular biology — Posted on 2019-03-21

1090 Evidence for the F200Y (TAC) mutation conferring benzimidazole resistance in a southern USA cattle population of Haemonchus placei spreading from a single emergence

Chaudhry, U.; Redman, E. M.; Kaplan, R.; Yazwinski, T.; Sargison, N.; Gilleard, J.

10.1101/578922 — molecular biology — Posted on 2019-03-21

1091 Dosing Time Matters

Ruben, M. D.; Smith, D. F.; FitzGerald, G. A.; Hogenesch, J. B.

10.1101/570119 — epidemiology — Posted on 2019-03-21

1092 WAT’s up!? – Organ-on-a-chip integrating human mature white adipose tissues for mechanistic research and pharmaceutical applications

Rogal, J.; Binder, C.; Kromidas, E.; Probst, C.; Schneider, S.; Schenke-Layland, K.; Loskill, P.

10.1101/585141 — bioengineering — Posted on 2019-03-21

1093 Inferring the quasipotential landscape of microbial ecosystems with topological data analysis

Chang, W. K.; Kelly, L.

10.1101/584201 — systems biology — Posted on 2019-03-21

1094 Intraventricular CXCL12 is neuroprotective and increases neurogenesis in a murine model of stroke

zamproni, l.; Porcionatto, M.

10.1101/584565 — neuroscience — Posted on 2019-03-21

1095 Leveraging non-human primate multisensory neurons and circuits in assessing consciousness theory

Noel, J.-P.; Ishizawa, Y.; Patel, S.; Eskandar, E.; Wallace, M.

10.1101/584516 — neuroscience — Posted on 2019-03-21

1096 EEG-fMRI reveals rapid representation of personal relevance of faces in social cognition and reward-related brain regions

Bayer, M.; Berhe, O.; Dziobek, I.; Johnstone, T.

10.1101/585133 — neuroscience — Posted on 2019-03-21

1097 Mitigating Pandemic Risk with Influenza A Virus Field Surveillance at a Swine-Human Interface

Rambo-Martin, B. L.; Keller, M. W.; Wilson, M. M.; Nolting, J. M.; Anderson, T. K.; Vincent, A. L.; Bagal, U.; Jang, Y.; Neuhaus, E. B.; Davis, C. T.; Bowman, A. S.; Wentworth, D. E.; Barnes, J. R.

10.1101/585588 — microbiology — Posted on 2019-03-21

1098 Dietary intake regulates the circulating inflammatory monocyte pool

Jordan, S.; Tung, N.; Casanova-Acebes, M.; Chang, C.; Cantoni, C.; Zhang, D.; Wirtz, T. H.; Naik, S.; Rose, S. A.; Brocker, C. N.; Gainullina, A.; Maier, B. B.; LeRoith, D.; Gonzalez, F. J.; Meissner, F.; Ochando, J.; Rahman, A.; Chipuk, J. E.; Artyomov, M. N.; Frenette, P. S.; Piccio, L.; Berres, M.-L.; Gallagher, E. J.; Merad, M.

10.1101/582346 — immunology — Posted on 2019-03-21

1099 Re-evaluation of homozygous lethality for EF1A indel polymorphism in Pisaster ochraceus

Wares, J. P.; Duffin, P. J.

10.1101/584235 — evolutionary biology — Posted on 2019-03-21

1100 Pathogen evolution when transmission and virulence are stochastic

Aavani, P.; Rice, S. H.

10.1101/584425 — evolutionary biology — Posted on 2019-03-21

1101 Genomics of expanded avian sex chromosomes shows that certain chromosomes are predisposed towards sex-linkage in vertebrates

Sigeman, H.; Ponnikas, S.; Chauhan, P.; Dierickx, E.; Brooke, M. d. L.; Hansson, B.

10.1101/585059 — evolutionary biology — Posted on 2019-03-21

1102 Adaptive introgression as a driver of local adaptation to climate in European white oaks

Leroy, T.; Louvet, J.-M.; Lalanne, C.; Le Provost, G.; Labadie, K.; Aury, J.-M.; Delzon, S.; Plomion, C.; Kremer, A.

10.1101/584847 — evolutionary biology — Posted on 2019-03-21

1103 Development of senescence biomarkers in the common woodlouse

Depeux, C.; Samba-Louaka, A.; Becking, T.; Braquart-Varnier, C.; Moreau, J.; Lemaitre, J.-F.; Laverre, T.; Paulhac, H.; Dechaume-Montcharmont, F.-X.; Gaillard, J.-M.; Beltran-Becg, S.

10.1101/583914 — evolutionary biology — Posted on 2019-03-21

1104 Immune and environment-driven gene expression during invasion: An eco-immunological application of RNA-Seq

Selechnik, D.; Richardson, M. F.; Shine, R.; Brown, G. P.; Rollins, L. A.

10.1101/583617 — ecology — Posted on 2019-03-21

1105 Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect

Johnson, K. E.; Howard, G.; Mo, W.; Strasser, M. K.; Lima, E. A. B. F.; Huang, S.; Brock, A.

10.1101/585216 — cancer biology — Posted on 2019-03-21

1106 Laser Recording of Subcellular Neuron Activities

Chen, Y.-C.; Li, X.; Zhu, H.; Weng, W.-H.; Tan, X.; Chen, Q.; Wang, X.; Fan, X.

10.1101/584938 — bioengineering — Posted on 2019-03-21

1107 Biologically inspired model of associative memory storage with noisy neurons and synapses

Zhang, C.; Zhang, D.; Stepanyants, A.

10.1101/583922 — neuroscience — Posted on 2019-03-21

1108 High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome

Moldovan, L. I.; Hansen, T. B.; Veno, M. T.; Hauge Okholm, T. L.; Levin Andersen, T.; Hager, H.; Iversen, L.; Kjems, J.; Johansen, C.; Kristensen, L. S.

10.1101/581066 — molecular biology — Posted on 2019-03-21

1109 Chimeric LuxR Transcription Factors Rewire Natural Product Regulation

Mukherji, R.; Chowdhury, S.; Stallforth, P.

10.1101/584987 — microbiology — Posted on 2019-03-21

1110 Enhanced replication of mouse adenovirus type 1 following virus-induced degradation of protein kinase R (PKR)

Goodman, D. E.; Pretto-Kernahan, C. D.; Krepostman, T. A.; Carnahan, K. E.; Spindler, K. R.

10.1101/584680 — microbiology — Posted on 2019-03-21

1111 Neuro-genetic plasticity of Caenorhabditis elegans behavioral thermal tolerance

Stegeman, G. W.; Medina, D.; Cutter, A. D.; Ryu, W. S.

10.1101/583120 — genetics — Posted on 2019-03-21

1112 Neuronal function and dopamine signaling evolve at high temperature in Drosophila

Jaksic, A. M.; Karner, J.; Nolte, V.; Hsu, S.-K.; Barghi, N.; Mallard, F. J.; Otte, K. A.; Svecnjak, L.; Senti, K. A.; Schlotterer, C.

10.1101/585422 — evolutionary biology — Posted on 2019-03-21

1113 Distinctive airway microbial ecology of smokers and asthmatics

Turek, E. M.; Cox, M. J.; Hunter, M.; Hui, J.; James, P.; Willis-Owen, S. A.; Cuthbertson, L.; James, A.; Musk, A. W.; Moffatt, M. F.; Cookson, W. O.

10.1101/583559 — ecology — Posted on 2019-03-21

1114 A Truly Injectable Neural Stimulation Electrode Made From an In-Body Curing Polymer/Metal Composite

Trevathan, J. K.; Baumgart, I.; Nicolai, E. N.; Gosink, B. A.; Asp, A. J.; Settell, M. L.; Polaconda, S. R.; Malerick, K.; Brodnick, S. K.; Zeng, W.; Knudsen, B. E.; McConico, A. L.; Sanger, Z.; Lee, J. H.; Aho, J. M.; Suminski, A. J.; Ross, E. K.; Lujan, J. L.; Weber, D. J.; Williams, J. C.; Franke, M.; Ludwig, K. A.; Shoffstall, A. J.

10.1101/584995 — bioengineering — Posted on 2019-03-21

1115 Population productivity of shovelnose rays: inferring the potential for recovery

D'Alberto, B. M.; Carlson, J. K.; Pardo, S. A.; Simpfendorfer, C. A.

10.1101/584557 — zoology — Posted on 2019-03-21

1116 Chemical degumming increases larvae size and facilitates commercial production of Lumpfish (Cyclopterus lumpus) eggs

Pooley, C. L.; Berwick, M. G.; Garcia de Leaniz, C.

10.1101/583641 — zoology — Posted on 2019-03-21

1117 Fundamental Theory of the Evolution Force (FTEF): Gene Engineering utilizing Synthetic Evolution Artificial Intelligence (SYN-AI)

Davis, L. K.; Uppu, R. M.

10.1101/585042 — synthetic biology — Posted on 2019-03-21

1118 Evaluating the Role of Fish as Surrogates for Amphibians in Pesticide Ecological Risk Assessment

Glaberman, S.; Kiwiet, J.; Aubee, C.

10.1101/584417 — pharmacology and toxicology — Posted on 2019-03-21

1119 Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology

Rodriguez, G. A.; Barrett, G. M.; Duff, K. E.; Hussaini, A.

10.1101/487405 — neuroscience — Posted on 2019-03-21

1120 A distinct class of bursting neurons with strong gamma synchronization and stimulus selectivity in monkey V1

Onorato, I.; Neuenschwander, S.; Hoy, J.; Lima, B.; Rocha, K.-S.; Broggini, A. C.; Uran, C.; Spyropoulos, G.; Womelsdorf, T.; Fries, P.; Niell, C.; Singer, W.; Vinck, M.

10.1101/583955 — neuroscience — Posted on 2019-03-21

1121 microRNA mir-598-3p mediates susceptibility to stress-enhancement of remote fear memory

Jones, M. E.; Sillivan, S. E.; Jamieson, S.; Rumbaugh, G.; Miller, C. A.

10.1101/584326 — neuroscience — Posted on 2019-03-21

1122 Dynamics of functional networks for syllable and word-level processing

Rimmele, J. M.; Sun, Y.; Michalareas, G.; Ghitza, O.; Poeppel, D.

10.1101/584375 — neuroscience — Posted on 2019-03-21

1123 Stochastic Models of Polymerization Based Axonal Actin Transport

Chakrabarty, N.; Jung, P.

10.1101/583716 — neuroscience — Posted on 2019-03-21

1124 Comparing self- and hetero-metacognition in the absence of verbal communication

Vuillaume, L.; Martin, J.-R.; Sackur, J.; Cleeremans, A.

10.1101/585240 — neuroscience — Posted on 2019-03-21

1125 Metatranscriptomics as a tool to identify fungal species and subspecies in mixed communities

Rossetto Marcelino, V.; Irinyi, L.; Eden, J.-S.; Meyer, W.; Holmes, E. C.; Sorrell, T. C.

10.1101/584649 — molecular biology — Posted on 2019-03-21

1126 A bacterial endosymbiont enables fungal immune evasion during fatal mucormycete infection

Itabangi, H.; Sephton-Clark, P.; Zhou, X.; Insua, I.; Probert, M.; Correia, J.; Moynihan, P.; Gebremariam, T.; Gu, Y.; Lin, L.; Ibrahim, A. S.; Brown, G. D.; King, J. S.; Fernandez-Trillo, F.; Ballou, E. R.; Voelz, K.

10.1101/584607 — microbiology — Posted on 2019-03-21

1127 Shallow metagenomics with Nanopore sequencing in canine fecal microbiota improved bacterial taxonomy and identified an uncultured CrAssphage

Cusco, A.; Salas, A.; Torre, C.; Francino, O.

10.1101/585067 — microbiology — Posted on 2019-03-21

1128 Assays for monitoring Toxoplasma gondii infectivity in the laboratory mouse

Wang, Q.; Sibley, L. D.

10.1101/584474 — microbiology — Posted on 2019-03-21

1129 Tracking human population structure through time from whole genome sequences

Wang, K.; Mathieson, I.; O'Connell, J.; Schiffels, S.

10.1101/585265 — evolutionary biology — Posted on 2019-03-21

1130 Structural color in Junonia butterflies evolves by tuning scale lamina thickness

Thayer, R. C.; Allen, F. I.; Patel, N. H.

10.1101/584532 — evolutionary biology — Posted on 2019-03-21

1131 In silico design of glyco-D,L-peptide antiviral molecules.

Agostini, L.; Morosetti, S.

10.1101/583765 — bioinformatics — Posted on 2019-03-21

1132 Live-cell Imaging Analysis of Antimycin-Type Depsipeptides via Bioorthogonal Stimulated Raman Scattering Microscopy

Seidel, J. A.; Miao, Y.; Porterfield, W.; Cai, W.; Zhu, X.; Kim, S.-J.; Hu, F.; Bhattarai-Kline, S.; Min, W.; Zhang, W.

10.1101/583252 — bioengineering — Posted on 2019-03-21

1133 Trans-endothelial insulin transport is impaired in skeletal muscle capillaries of obese male mice.

Williams, I. M.; McClatchey, P. M.; Bracy, D. P.; Bonner, J. S.; Valenzuela, F. A.; Wasserman, D. H.

10.1101/585372 — physiology — Posted on 2019-03-21

1134 Integrated Open-Source Software for Multiscale Electrophysiology

Nasiotis, K.; Cousineau, M.; Tadel, F.; Peyrache, A.; Leahy, R.; Pack, C.; Baillet, S.

10.1101/584185 — neuroscience — Posted on 2019-03-21

1135 Untapped viral diversity in global soil metagenomes

Graham, E. B.; Paez-Espino, D.; Brislawn, C.; Neches, R. Y.; Hofmockel, K. S.; Wu, R.; Kyrpides, N. C.; Jansson, J. K.; McDermott, J. E.

10.1101/583997 — microbiology — Posted on 2019-03-21

1136 E-ChRPs: Engineered Chromatin Remodeling Proteins for Precise Nucleosome Positioning

Donovan, D. A.; Crandall, J. G.; Banks, O. G.; Jensvold, Z. D.; McKnight, L. E.; McKnight, J. N.

10.1101/480913 — genetics — Posted on 2019-03-21

1137 Graphical factorial surveys reveal the acceptability of wildlife observation at protected areas.

Cerri, J.; Bertolino, S.; Martinelli, E.

10.1101/580688 — ecology — Posted on 2019-03-21

1138 CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors

Walens, A.; DiMarco, A. V.; Lupo, R.; Kroger, B. R.; Damrauer, J. S.; Alvarez, J. V.

10.1101/584979 — cancer biology — Posted on 2019-03-21

1139 Adaptive optics allows 3D STED-FCS measurements in the cytoplasm of living cells

Barbotin, A.; Galiani, S.; Urbancic, I.; Eggeling, C.; Booth, M.

10.1101/584870 — biophysics — Posted on 2019-03-21

1140 Decomposing information into copying versus transformation

Kolchinsky, A.; Corominas-Murtra, B.

10.1101/584771 — biophysics — Posted on 2019-03-21

1141 Representation of task episodes in human cortical networks

Wen, T.; Duncan, J.; Mitchell, D. J.

10.1101/582858 — neuroscience — Posted on 2019-03-21

1142 A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral-shape to coccoids

El Mortaji, L.; Marsin, S.; Rifflet, A.; Boneca, I. G.; Radicella, P.; Pehau-Arnaudet, G.; De Reuse, H.

10.1101/585380 — microbiology — Posted on 2019-03-21

1143 Mucosal microbiota and metabolome along the intestinal tracts reveals location specific relationship

Yuan, C.; Graham, M.; Staley, C.; Subramanian, S.

10.1101/454496 — genomics — Posted on 2019-03-21

1144 Clinical features of bloodstream infections caused by the two dominant clones of endemic methicillin-resistant Staphylococcus aureus

Dupper, A.; Sullivan, M. J.; Chacko, K. I.; Mishkin, A.; Ciferri, B.; Kumaresh, A.; Berbel Caban, A.; Oussenko, I.; Beckford, C.; Zeitouni, N. E.; Sebra, R.; Hamula, C.; Smith, M.; Kasarskis, A.; Patel, G.; McBride, R. B.; van Bakel, H.; Altman, D. R.

10.1101/501833 — epidemiology — Posted on 2019-03-21

1145 Lineage does not regulate the connectivity of projection neurons in the mouse olfactory bulb

Lois, C.; Sanchez-Guardado, L.

10.1101/584805 — developmental biology — Posted on 2019-03-21

1146 Modular tissue-specific regulation of doublesex underpins sexually dimorphic development in Drosophila

Rice, G.; Barmina, O.; Luecke, D.; Hu, K.; Arbeitman, M.; Kopp, A.

10.1101/585158 — developmental biology — Posted on 2019-03-21

1147 High Epha1 expression is a potential cell surface marker for embryonic neuro-mesodermal progenitors

de Lemos, L.; Novoa, A.; Mallo, M.

10.1101/584524 — developmental biology — Posted on 2019-03-21

1148 N-linked glycans confer protein stability and modulate multidrug efflux pump assembly in Campylobacter jejuni

Abouelhadid, S.; Raynes, J.; Bui, T. T. T.; Cuccui, J.; Wren, B. W.

10.1101/585463 — biochemistry — Posted on 2019-03-21

1149 RACK1 on and off the ribosome

Johnson, A. G.; Lapointe, C. P.; Wang, J.; Corsepius, N. C.; Choi, J.; Fuchs, G.; Puglisi, J. D.

10.1101/582635 — biochemistry — Posted on 2019-03-21

1150 The C. elegans SET-2 histone methyltransferase maintains germline fate by preventing progressive transcriptomic deregulation across generations

Robert, V. J.; Knutson, A. K.; Rechtsteiner, A.; Yvert, G.; Strome, S.; Palladino, F.

10.1101/583799 — genetics — Posted on 2019-03-21

1151 The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network

Grocott, T.; Lozano-Velasco, E.; Mok, G. F.; Munsterberg, A. E.

10.1101/583807 — developmental biology — Posted on 2019-03-21

1152 Opposing modulation of Cx26 gap junctions and hemichannels by CO2

Nijjar, S.; Maddison, D.; Meigh, L.; de Wolf, E.; Rodgers, T.; Cann, M. J.; Dale, N.

10.1101/584722 — cell biology — Posted on 2019-03-21

1153 A NOVEL MECHANISM FOR NF-κB-ACTIVATION VIA IκB-AGGREGATION: IMPLICATIONS FOR HEPATIC MALLORY-DENK-BODY INDUCED INFLAMMATION

Liu, Y.; Trnka, M. J.; Guan, S.; Kwon, D.; Kim, D.-H.; Chen, J.-J.; Greer, P. A.; Burlingame, A. L.; Correia, M. A.

10.1101/585497 — cell biology — Posted on 2019-03-21

1154 Characterising memory loss in patients with autoimmune limbic encephalitis hippocampal lesions

Lad, M.; Mullally, S. L.; Houston, A. L.; Kelly, T.; Griffiths, T. D.

10.1101/579979 — neuroscience — Posted on 2019-03-21

1155 Rhythmic chromatin interactions with lamin B1 reflect stochasticity in variable lamina-associated domains during the circadian cycle

Brunet, A.; Forsberg, F.; Collas, P.

10.1101/584011 — genomics — Posted on 2019-03-21

1156 Patterns of diverse gene functions in genomic neighborhoods predict gene function and phenotype

Mihelcic, M.; Smuc, T.; Supek, F.

10.1101/582577 — genomics — Posted on 2019-03-21

1157 Simulation of Red Blood Cell Migration in Small Arterioles: Effect of Cytoplasmic Viscosity

Saadat, A.; Guido, C. J.; Shaqfeh, E. S. G.

10.1101/572933 — biophysics — Posted on 2019-03-21

1158 lionessR: single-sample network reconstruction in R

Kuijjer, M. L.; Quackenbush, J.; Glass, K.

10.1101/582098 — bioinformatics — Posted on 2019-03-21

1159 Statistical learning shapes neural sequence representations

Henin, S.; Turk-Browne, N.; Friedman, D.; Liu, A.; Dugan, P.; Flinker, A.; Doyle, W.; Devinsky, O.; Melloni, L.

10.1101/583856 — neuroscience — Posted on 2019-03-21

1160 Conduit integrity is compromised during acute lymph node expansion

Martinez, V. G.; Pankova, V.; Krasny, L.; Singh, T.; White, I. J.; Benjamin, A. C.; Dertschnig, S.; Horsnell, H. L.; Kriston-Vizi, J.; Burden, J. J.; Huang, P. H.; Tape, C. J.; Acton, S. E.

10.1101/527481 — immunology — Posted on 2019-03-21

1161 Profiling Gene Specific Changes to RNA Editome in Preeclampsia

Hasan, S.; Robbani, S. M.; Afroze, T.; Ahsan, G. U.; Hossain, M. M.

10.1101/584672 — genomics — Posted on 2019-03-21

1162 Improving the accuracy of single turnover active fluorometry (STAF) for the estimation of phytoplankton primary productivity (PhytoPP)

Boatman, T. G.; Geider, R. J.; Oxborough, K.

10.1101/583591 — plant biology — Posted on 2019-03-21

1163 Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against autoimmune diseases

Liu, R.; Chen, Y.; Wang, S.; Cui, Y.; Zhang, X.; Lei, Z.-N.; Hettinghouse, A.; Liu, J.; Fu, W.; Chen, Z.-S.; Liu, C.

10.1101/584540 — molecular biology — Posted on 2019-03-21

1164 Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies novel methylation loci

Smith, A. K.; Ratanatharathorn, A.; Maihofer, A. X.; Naviaux, R. K.; Aiello, A. E.; Amstadter, A. B.; Ashley-Koch, A. E.; Baker, D. G.; Beckham, J. C.; Boks, M. P.; Bromet, E.; Dennis, M.; Galea, S.; Garrett, M. E.; Geuze, E.; Guffanti, G.; Hauser, M. A.; Katrinli, S.; Kilaru, V.; Kessler, R. C.; Kimbrel, N. A.; Koenen, K. C.; Kuan, P.-F.; Li, K.; Logue, M. W.; Lori, A.; Luft, B. J.; Miller, M. W.; Naviaux, J. C.; Nugent, N. R.; Qin, X.; Ressler, K. J.; Risbrough, V. B.; Rutten, B. P. F.; Stein, M. B.; Ursano, R. J.; Vermetten, E.; Vinkers, C. H.; Wang, L.; Youssef, N. A.; INTRuST Clinical Con

10.1101/585109 — genomics — Posted on 2019-03-21

1165 Universal surface-to-volume scaling and aspect ratio homeostasis in rod-shaped bacteria

Ojkic, N.; Serbanescu, D.; Banerjee, S.

10.1101/583989 — biophysics — Posted on 2019-03-21

1166 Multiple mechanisms link prestimulus neural oscillations to sensory responses

Iemi, L.; Busch, N. A.; Laudini, A.; Haegens, S.; Samaha, J.; Villringer, A.; Nikulin, V. V.

10.1101/461558 — neuroscience — Posted on 2019-03-21

1167 Seasonal and geographic variation in insecticide resistance in Aedes aegypti among four cities in southern Ecuador

Ryan, S.; Mundis, S. J.; Aguirre, A.; Lippi, C. A.; Beltran, E.; Heras, F.; Sanchez, V.; Borbor-Cordova, M. J.; Sippy, R.; Stewart-Ibarra, A. M.; Neira, M. V.

10.1101/441360 — epidemiology — Posted on 2019-03-21

1168 The role of feedback from the auditory cortex in shaping responses to sounds in inferior colliculus

Blackwell, J. M.; Rao, W.; De Biasi, M.; Geffen, M. N.

10.1101/584334 — neuroscience — Posted on 2019-03-21

1169 Changes in the Biodiversity Intactness Index in tropical and subtropical forest biomes, 2001-2012.

De Palma, A.; Hoskins, A.; Gonzalez, R. E.; Newbold, T.; Sanchez-Ortiz, K.; Ferrier, S.; Purvis, A.

10.1101/311688 — ecology — Posted on 2019-03-21

1170 Molecular mechanisms of Evening Complex activity in Arabidopsis

Silva, C.; Nayak, A.; Lai, X.; Hugouvieux, V.; Jung, J.-h.; Jourdain, A.; Lopez-Vidriero, I.; Manuel Franco-Zorrilla, J.; Parcy, F.; Panigrahi, K.; Wigge, P.; Nanao, M.; Zubieta, C.

10.1101/584854 — plant biology — Posted on 2019-03-21

1171 Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in histone H3 Lys-4 trimethylation independently from histone H2B monoubiquitination

Fiorucci, A.-S.; Bourbousse, C.; Concia, L.; Rougee, M.; Deton-Cabanillas, A.-F.; Zabulon, G.; Layat, E.; Latrasse, D.; Kim, S.; Chaumont, N.; Lombard, B.; Stroebel, D.; Lemoine, S.; Mohammad, A.; Blugeon, C.; Loew, D.; Bailly, C.; Bowler, C.; Benhamed, M.; Barneche, F.

10.1101/583724 — plant biology — Posted on 2019-03-21

1172 Leaf shape is a predictor of fruit quality and cultivar performance in tomato

Rowland, S. D.; Zumstein, K.; Nakayama, H.; Cheng, Z.; Flores, A. M.; Chitwood, D. H.; Maloof, J. N.; Sinha, N. R.

10.1101/584466 — plant biology — Posted on 2019-03-21

1173 Biophysical modeling of VIM to assess contributions of oscillatory activity to essential tremor

Lee, S.; Segar, D. J.; Asaad, W.; Jones, S.

10.1101/339846 — neuroscience — Posted on 2019-03-21

1174 Sex differences in gene expression in the human fetal brain

O'Brien, H. E.; Hannon, E.; Jeffries, A. R.; Davies, W.; Hill, M. J.; Anney, R. J.; O'Donovan, M. C.; Mill, J.; Bray, N. J.

10.1101/483636 — genomics — Posted on 2019-03-21

1175 Mutational profiling of lipomas

Kanojia, D.; Dakle, P.; Mayakonda, A.; Parameswaran, R.; Puhaindran, M. E.; Min, V. L. K.; Madan, V.; Koeffler, H. P.

10.1101/585307 — genomics — Posted on 2019-03-21

1176 A meta-analysis of genome-wide association studies of epigenetic age acceleration

Gibson, J.; Russ, T.; Clarke, T.-K.; Howard, D. M.; Evans, K.; Walker, R. M.; Bermingham, M.; Morris, S.; Campbell, A.; Hayward, C.; Murray, A.; Porteous, D.; Horvath, S.; Lu, A.; McIntosh, A.; Whalley, H.; Marioni, R.

10.1101/585299 — genetics — Posted on 2019-03-21

1177 Clinical pattern of antibiotic overuse and misuse in primary healthcare hospitals in the southwest of China

Chang, Y.; Chusri, S.; Sangthong, R.; McNeil, E.; Hu, J.; Du, W.; Li, D.; Fan, X.; Zhou, H.; Chongsuvivatwong, V.; Tang, L.

10.1101/585257 — epidemiology — Posted on 2019-03-21

1178 The land-use dynamics of potato agrobiodiversity in the highlands of central Peru: a case study of spatial-temporal management across farming landscapes

Arce Indacochea, A.; de Haan, S.; Juarez, H.; Plasencia, F.; Burra, D.; Ccanto, R.; Polreich, S.; Scurrah, M.

10.1101/585273 — ecology — Posted on 2019-03-21

1179 miRspongeR: an R/Bioconductor package for the identification and analysis of miRNA sponge interaction networks and modules

Zhang, J.; Liu, L.; Xu, T.; Xie, Y.; Zhao, C.; Li, J.; Le, T. D.

10.1101/507749 — bioinformatics — Posted on 2019-03-21

1180 The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Negatively Regulating Th17 Response

Gupta, G.; Jia, P.; Sharma, R.; Zayats, R.; Viana, S. M.; Shan, L.; Mou, Z.; Boaventura, V. S.; Barral, A.; Murooka, T. T.; Soussi-Gounni, A.; de Oliveira, C. I.; Uzonna, J. E.

10.1101/585315 — immunology — Posted on 2019-03-21

1181 Three-dimensional genome reorganization during mouse spermatogenesis

Luo, Z.; Wang, X.; Wang, R.; Chen, J.; Chen, Y.; Xu, Q.; Cao, J.; Gong, X.; Wu, J.; Yang, Y.; Li, W.; Han, C.; Sun, F.; Song, X.

10.1101/585281 — genomics — Posted on 2019-03-21

1182 Self-reported sleep duration and daytime napping are associated with renal hyperfiltration and microalbuminuria in apparently healthy Chinese population

Ye, Y.; ZHANG, L.; YAN, W.; WANG, A.; WANG, W.; GAO, Z.; TANG, X.; YAN, L.; WAN, Q.; LUO, Z.; QIN, G.; CHEN, L.; WANG, S.; Wang, Y.; MU, Y.

10.1101/585190 — epidemiology — Posted on 2019-03-21

1183 Development and characterization of phytosterol nanoemulsions and self-microemulsifying drug delivery systems

Chuanxun, Y.; Xueru, Z.; Risheng, J.

10.1101/585166 — biophysics — Posted on 2019-03-21

1184 Long-term iron deficiency and iron supplementation exacerbate acute DSS-induced colitis and are associated with significant dysbiosis

Mahalhal, A.; Burkitt, M. D.; Duckworth, C. A.; Hold, G. L.; Campbell, B. J.; Pritchard, D. M.; Probert, C. S.

10.1101/585174 — pathology — Posted on 2019-03-21

1185 The principle of inverse effectiveness in audiovisual speech perception

van Wanrooij, M. M.; van de Rijt, L. P. H.; Roye, A.; Mylanus, E. A. M.; van Opstal, A. J.

10.1101/585182 — neuroscience — Posted on 2019-03-21

1186 Effect of different forage-to-concentrate ratios on the structure of rumen bacteria and its relationship with nutrition levels and real-time methane production in sheep

Li, R.; Teng, Z.; Lang, C.; Zhou, H.; Zhong, W.; Ban, Z.; Yan, X.; Yang, H.; Farouk, M. H.; Lou, Y.

10.1101/585208 — microbiology — Posted on 2019-03-21

1187 Method to generate growth and degrowth models obtained from combinations of existing models applied to agrarian sciences

Santos, A.; Moreira, G. R.; Gomes-Silva, F.; Brito, C. C. R. d.; Costa, M. L.; Pereira, L. G. R.; Mauricio, R. M.; Azevedo, J. A. G. d.; Pereira, J. M.; Ferreira, A. L.; Filho, M. C.

10.1101/585224 — developmental biology — Posted on 2019-03-21

1188 Decoupling sensory from decisional choice biases in perceptual decision making

Linares, D.; Aguilar-Lleyda, D.; Lopez-Moliner, J.

10.1101/062380 — neuroscience — Posted on 2019-03-21

1189 Genetics and evidence for balancing selection of a sex-linked colour polymorphism in a songbird

Kim, K.-W.; Jackson, B. C.; Zhang, H.; Toews, D. P. L.; Taylor, S. A.; Greig, E. I.; Lovette, I. J.; Liu, M. M.; Davison, A.; Griffith, S. C.; Zeng, K.; Burke, T.

10.1101/437111 — evolutionary biology — Posted on 2019-03-21

1190 Multiplexing cell-cell communication

Sexton, J. T.; Tabor, J. J.

10.1101/584664 — synthetic biology — Posted on 2019-03-21

1191 Acute lymphoblastic leukemia cells image analysis with deep bagging ensemble learning

Liu, Y.; Long, F.

10.1101/580852 — pathology — Posted on 2019-03-21

1192 Relief from nitrogen starvation entails quick unexpected down-regulation of glycolytic/lipid metabolism genes in enological Saccharomyces cerevisiae

Tesniere, C.; Bessiere, C.; Pradal, M.; Sanchez, I.; Blondin, B.; Bigey, F.

10.1101/428979 — microbiology — Posted on 2019-03-21

1193 variant2literature: full text literature search for genetic variants

Lin, Y.-H.; Lu, Y.-C.; Hsu, J. S.; Lee, K.-H.; Cheng, Y.-W.; Chen, Y.-C.; Chen, T.-F.; Tu, C.-T.; Hsu, C.-M.; Chou, C.-C.; Chen, P.-L.; Tu, Y.-C. E.; Chen, C.-Y.

10.1101/583450 — genetics — Posted on 2019-03-21

1194 An Exon Skipping Screen Identifies Antitumor Drugs That Are Potent Modulators of Pre-mRNA Splicing, Suggesting New Therapeutic Applications

Shi, Y.; Bray, W.; Smith, A. J.; Zhou, W.; Calaoagan, J.; Lagisetti, C.; Sambucetti, L.; Crews, P.; Lokey, R. S.; Webb, T. R.

10.1101/584441 — cancer biology — Posted on 2019-03-21

1195 Enchained growth and cluster dislocation: a possible mechanism for microbiota homeostasis

Bansept, F.; Moor-Schumann, K.; Diard, M.; Hardt, W.-D.; Wetter Slack, E.; Loverdo, C.

10.1101/298059 — biophysics — Posted on 2019-03-21

1196 The Arrival of Steppe and Iranian Related Ancestry in the Islands of the Western Mediterranean

Fernandes, D. M.; Mittnik, A.; Olalde, I.; Lazaridis, I.; Cheronet, O.; Rohland, N.; Mallick, S.; Bernardos, R.; Broomandkhoshbacht, N.; Carlsson, J.; Culleton, B. J.; Ferry, M.; Gamarra, B.; Lari, M.; Mah, M.; Michel, M.; Modi, A.; Novak, M.; Oppenheimer, J.; Sirak, K. A.; Stewardson, K.; Vai, S.; Camaros, E.; Calo, C.; Catalano, G.; Cueto, M.; Forgia, V.; Lozano, M.; Marini, E.; Micheletti, M.; Micciche, R. M.; Palombo, M. R.; Ramis, D.; Schimmenti, V.; Sureda, P.; Teira, L.; Teschler-Nicola, M.; Kennett, D. J.; Lalueza-Fox, C.; Patterson, N.; Sineo, L.; Caramelli, D.; Pinhasi, R.; Reich, D.

10.1101/584714 — genomics — Posted on 2019-03-21

1197 Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts

Georgakopoulos-Soares, I.; Koh, G.; Jiricny, J.; Hemberg, M.; Nik-Zainal, S.

10.1101/584342 — genomics — Posted on 2019-03-21

1198 Moments reconstruction and local dynamic range compression of high order Superresolution Optical Fluctuation Imaging

Yi, X.; Son, S.; Ando, R.; Miyawaki, A.; Weiss, S.

10.1101/500819 — bioengineering — Posted on 2019-03-21

1199 Identification of histological features to predict MUC2 expression in colon cancer tissues

Periyakoil, P. K.; Clarke, M.; Sahoo, D.

10.1101/584292 — cancer biology — Posted on 2019-03-21

1200 Long-term exposure to daily ethanol injections in DBA2/J and Swiss mice: Lessons for the interpretation of ethanol sensitization

Didone, V.; van Ingelgom, T.; Tirelli, E.; Quertemont, E.

10.1101/584102 — neuroscience — Posted on 2019-03-21

1201 Implementation of Design of Experiments (DOE) for Optimization of Feeding Strategy and Glyco-Engineering of Trastuzumab Biosimilar

Mahboudi, R.; Samavat, S.; Afrah, A.; Khorshidtalab, M.; Fadaei Tehran, A.; Motahari, P.; Jafari, F.; Maleknia, S.

10.1101/584144 — bioengineering — Posted on 2019-03-21

1202 SULTA4A1 modulates synaptic development and function by promoting the formation of PSD-95/NMDAR complex

Verpelli, C.; Culotta, L.; Terragni, B.; Vinci, E.; Sessa, A.; Broccoli, V.; Mantegazza, M.

10.1101/583419 — neuroscience — Posted on 2019-03-21

1203 Heterologous Expression of Human Norovirus GII.4 VP1 Leads to Assembly of T=4 Virus-Like Particles

Devant, J.; Hofhaus, G.; Bhella, D.; Hansman, G.

10.1101/583385 — molecular biology — Posted on 2019-03-21

1204 Construction and validation of EGFP-expressing Staphylococcus aureus clinical strains for adhesion and internalization assays on epithelial cells

Charaoui-Boukerzaza, S.; Morgene, M. F.; Rigaill, J.; Audoux, E.; He, Z.; Grattard, F.; Carricajo, A.; Pozzetto, B.; Berthelot, P.; Botelho-Nevers, E.; Verhoeven, P. O.

10.1101/584086 — microbiology — Posted on 2019-03-21

1205 Evidence that viruses, particularly SIV, drove genetic adaptation in natural populations of eastern chimpanzees

Schmidt, J. M.; de Manuel, M.; Marques-Bonet, T.; Castellano, S.; Andres, A. M.

10.1101/582411 — evolutionary biology — Posted on 2019-03-21

1206 Seroprevalence of zoonotic diseases (leptospirosis and Japanese encephalitis) in swine in ten provinces of Vietnam: a Bayesian approach to estimate prevalence

Lee, H. S.; Thanh, T. L.; Ly, N. K.; Nguyen-Viet, H.; Thakur, K. K.; Grace, D.

10.1101/584151 — epidemiology — Posted on 2019-03-21

1207 Time-to-target explains task-dependent modulation of temporal feedback gain evolution

Cesonis, J.; Franklin, D.

10.1101/582874 — neuroscience — Posted on 2019-03-21

1208 Multiparasitism among Schoolchildren of Akonolinga, Nyong et Mfoumou Division, Centre Region of Cameroon

OYONO, M. G.; LEHMAN, L. G.; FOSSO, S.; BILONG BILONG, C. F.

10.1101/584318 — epidemiology — Posted on 2019-03-21

1209 Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension

Sindi, H.; Russomanno, G.; Kyeong Beom, J.; Abdul-Salam, V. B.; Chaudhry, B. Q.; Ainscough, A.; Szulcek, R.; Bogaard, H. J.; Morgan, C.; Pullamsetti, S. S.; Alzaydi, M.; Rhodes, C.; Grünig, E.; Eichstaedt, C.; Wilkins, M. R.; Wojciak-Stothard, B.

10.1101/583633 — cell biology — Posted on 2019-03-21

1210 Simulations reveal challenges to artificial community selection and possible strategies for success

Xie, L.; Yuan, A. E.; Shou, W.

10.1101/264689 — evolutionary biology — Posted on 2019-03-20

1211 treeClust improves protein co-regulation analysis due to robust selectivity for close linear relationships

Kustatscher, G.; Grabowski, P.; Rappsilber, J.

10.1101/578971 — systems biology — Posted on 2019-03-20

1212 Tuned normalization in perceptual decision-making circuits can explain seemingly suboptimal confidence behavior

Maniscalco, B.; Odegaard, B.; Grimaldi, P.; Cho, S. H.; Basso, M. A.; Lau, H.; Peters, M. A. K.

10.1101/558858 — neuroscience — Posted on 2019-03-20

1213 Prediction of combination therapies based on topological modeling of the immune signaling network in Multiple Sclerosis

Bernardo-Faura, M.; Rinas, M.; Wirbel, J.; Pertsovskaya, I.; Pliaka, V.; Messinis, D. E.; Vila, G.; Sakellaropoulos, T.; Faigle, W.; Stridh, P.; Behrens, J. R.; Olsson, T.; Martin, R.; Paul, F.; Alexopoulos, L. G. G.; Villoslada, P.; Saez-Rodriguez, J.

10.1101/541458 — systems biology — Posted on 2019-03-20

1214 Cross-transmission is not the source of new Mycobacterium abscessus infections in a multi-centre cohort of cystic fibrosis patients

Doyle, R. M.; Rubio, M.; Dixon, G.; Hartley, J.; Klein, N.; Coll, P.; Harris, K. A.

10.1101/582684 — microbiology — Posted on 2019-03-20

1215 Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration

Hsu, A. Y.; Wang, D.; Liu, S.; Lu, J.; Sobreira, R. S.; Bennin, D. A.; Huttenlocher, A.; Umulis, D. M.; Wan, J.; Deng, Q.

10.1101/574335 — immunology — Posted on 2019-03-20

1216 Non-lethal oxidative stress boosts bacterial survival and evolvability under lethal exposure

Rodriguez Rojas, A.; Kim, J.; Johnston, P. R.; Makarova, O.; Eravci, M.; Weise, C.; Hengge, R.; Rolff, J.

10.1101/575134 — evolutionary biology — Posted on 2019-03-20

1217 LSO:Ce Inorganic Scintillators are Biocompatible with Neuronal and Circuit Function

Bartley, A. F.; Abiraman, K.; Stewart, L. T.; Hossain, M. I.; Gahan, D. M.; Kamath, A. V.; Burdette, M. K.; Andrabe, S.; Foulger, S. H.; McMahon, L. L.; Dobrunz, L. E.

10.1101/579722 — neuroscience — Posted on 2019-03-20

Stark, S. M.; Frithsen, A.; Stark, C. E.

10.1101/577361 — neuroscience — Posted on 2019-03-20

1219 Host-pathogen transcriptomics of macrophages, Mucorales and their endosymbionts: a polymicrobial pas de trois

Sephton-Clark, P.; Munoz, J. F.; Itabangi, H.; Voelz, K.; Cuomo, C.; Ballou, E.

10.1101/580746 — microbiology — Posted on 2019-03-20

1220 A stable pollination environment limits current but not potential evolution of floral traits

Castellanos, M. C.; Montero-Pau, J.; Ziarsolo, P.; Blanca, J. M.; Canizares, J.; Pausas, J. G.

10.1101/581827 — evolutionary biology — Posted on 2019-03-20

1221 Frequent sugar feeding behavior by Aedes aegypti in Bamako, Mali makes them ideal candidates for control with attractive toxic sugar baits (ATSB)

Sisoko, F.; Junnila, A.; Traore, M.; Traore, S. F.; Doumbia, S.; Dembele, S. M.; Schlein, Y.; Gergely, P.; Xue, R.-d.; Arheart, K. L.; Revay, E. E.; Kravchenko, V. D.; Beier, J. C.; Muller, G. C.

10.1101/574095 — ecology — Posted on 2019-03-20

1222 Chemical screening pipeline for identification of specific plant autophagy modulators

Dauphinee, A. N.; Cardoso, C.; Dalman, K.; Ohlsson, J. A.; Berglund Fick, S.; Robert, S.; Hicks, G. R.; Bozhkov, P. V.; Minina, E. A.

10.1101/569327 — plant biology — Posted on 2019-03-20

1223 The interaction of compliance and activation on the force-length operating range and force generating capacity of skeletal muscle

Cox, S. M.; Easton, K. L.; Cromie Lear, M.; Marsh, R.; Delp, S.; Rubenson, J.

10.1101/580027 — physiology — Posted on 2019-03-20

1224 Experimental colitis drives enteric alpha-synuclein accumulation and Parkinson-like brain pathology

Grathwhohl, S.; Quansah, E.; Maroof, N.; Steiner, J. A.; Spycher, L.; Benmansour, F.; Duran-Pacheco, G.; Siebourg-Polster, J.; Oroszlan-Szovik, K.; Remy, H.; Haenggi, M.; Stawiski, M.; Sehlhausen, M.; Maliver, P.; Wolfert, A.; Emrich, T.; Madaj, Z.; Escobar Galvis, M. L.; Mueller, C.; Herrmann, A.; Brundin, P.; Britschgi, M.

10.1101/505164 — neuroscience — Posted on 2019-03-20

1225 Disentangling presentation and processing times in the brain

Caplette, L.; Ince, R. A. A.; Jerbi, K.; Gosselin, F.

10.1101/566042 — neuroscience — Posted on 2019-03-20

1226 Identification of Physiological Response Functions to Correct for Fluctuations in Resting-State fMRI related to Heart Rate and Respiration

Kassinopoulos, M.; Mitsis, G. D.

10.1101/512855 — neuroscience — Posted on 2019-03-20

1227 In vivo microscopy reveals the impact of Pseudomonas aeruginosa social interactions on host colonization

Rezzoagli, C.; Granato, E.; Kuemmerli, R.

10.1101/488262 — microbiology — Posted on 2019-03-20

1228 Parasite histones mediate leak and coagulopathy in cerebral malaria

Moxon, C. A.; Alhamdi, Y.; Storm, J.; Toh, J.; Ko, J. Y.; Murphy, G.; Taylor, T.; Seydel, K.; Kampondeni, S.; Potchen, M.; O'Donnell, J.; O'Regan, N.; Wang, G.; Garcia-Cardena, G.; Molyneux, M.; Craig, A.; Abrams, S.; Toh, C.-H.

10.1101/563551 — microbiology — Posted on 2019-03-20

1229 UK phenomics platform for developing and validating EHR phenotypes: CALIBER

Denaxas, S.; Gonzalez-Izquierdo, A.; Direk, K.; Fitzpatrick, N.; Fatemifar, G.; Banerjee, A.; Dobson, R.; Howe, L. J.; Kuan, V.; Lumbers, T.; Pasea, L.; Patel, R.; Shah, A. D.; Hingorani, A.; Sudlow, C.; Hemingway, H.

10.1101/539403 — epidemiology — Posted on 2019-03-20

1230 FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation

Hoffmann, I.; Richter, K. T.; Kschonsak, Y. T.; Vodicska, B.

10.1101/493791 — cell biology — Posted on 2019-03-20

1231 A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase

Buchan, K. D.; Prajsnar, T. K.; Ogryzko, N. V.; de Jong, N. W.; van Gent, M.; Kolata, J.; Foster, S. J.; Van Strijp, J. A. G. A.; Renshaw, S. A.

10.1101/456541 — immunology — Posted on 2019-03-20

1232 Efa6 protects axons and regulates their growth and branching through eliminating off-track microtubules at the cortex

Qu, Y.; Hahn, I.; Lees, M.; Parkin, J.; Voelzmann, A.; Dorey, K.; Rathbone, A.; Friel, C.; Allan, V.; Okenve-Ramos, P.; Sanchez-Soriano, N.; Prokop, A.

10.1101/385658 — cell biology — Posted on 2019-03-20

1233 Quantifying GC-biased gene conversion in great ape genomes using polymorphism-aware models

Borges, R.; Szöllosi, G.; Kosiol, C.

10.1101/380246 — genetics — Posted on 2019-03-20

1234 Tissue-specific MicroRNA Expression Alters Cancer Susceptibility Conferred by a TP53 Noncoding Variant

LI, Y.

10.1101/582478 — cancer biology — Posted on 2019-03-20

1235 Enhancing Boolean networks with continuous logical operators and edge tuning

Poret, A.; Monteiro Sousa, C.; Boissel, J.-P.

10.1101/584243 — bioinformatics — Posted on 2019-03-20

1236 Deep representation learning for domain adaptable classification of infrared spectral imaging data

Raulf, A. P.; Butke, J.; Kuepper, C.; Grosserueschkamp, F.; Gerwert, K.; Mosig, A.

10.1101/584227 — bioinformatics — Posted on 2019-03-20

1237 Non-proliferative adult neurogenesis in neural crest-derived stem cells isolated from human periodontal ligament.

Bueno, C.; Martinez-Morga, M.; Martinez, S.

10.1101/325613 — neuroscience — Posted on 2019-03-20

1238 Unveiling functional motions based on point mutations in biased signaling systems: A normal mode study on Nerve Growth Factor bound to TrkA

De Resende Lara, P. T.; Perahia, D.; Scott, A. L.; Braz, A. S. K.

10.1101/584300 — bioinformatics — Posted on 2019-03-20

1239 Time-series expression profiling of sugarcane leaves infected with Puccinia kuehnii reveals an ineffective defense system leading to susceptibility

Correr, F. H.; Kenichi Hosaka, G.; Perez Gomez, S. G.; Cicarelli Cia, M.; Barros Monteiro Vitorello, C. A.; Aranha Camargo, L. E.; Massola Junior, N. S.; Sampaio Carneiro, M.; Rodrigues Alves Margarido, G.

10.1101/584276 — genomics — Posted on 2019-03-20

1240 Cabbage stem flea beetles (Psylliodes chrysocephala L.) susceptibility to pyrethroids and tolerance to thiacloprid in the Czech Republic

Stara, J.; Kocourek, F.

10.1101/584250 — zoology — Posted on 2019-03-20

1241 Microbial metabolite deoxycholic acid shapes microbiota against Campylobacter jejuni chicken colonization

Alrubaye, B.; Abraha, M.; Almansour, A.; Bansal, M.; Wang, H.; Kwon, Y. M.; Huang, Y.; Hargis, B.; Sun, X.

10.1101/584284 — microbiology — Posted on 2019-03-20

1242 Cardiac remodeling after six weeks of high-intensity interval training to exhaustion in endurance-trained males

Mahjoub, H.; Le Blanc, O.; Paquette, M.; Imhoff, S.; Labrecque, L.; Drapeau, A.; Poirier, P.; Bedard, E.; Pibarot, P.; Brassard, P.

10.1101/582924 — physiology — Posted on 2019-03-20

1243 A normative study of modified spatial context memory test in middle and older individuals

Kuo, H.-C.; Wang, H.-M.; Huang, Y.-P.; Kuo, H.-Y.

10.1101/584136 — neuroscience — Posted on 2019-03-20

1244 Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation

Tsutsumi, T.; Nagaoka, T.; Yoshida, T.; Wang, L.; Kuriyama, S.; Suzuki, Y.; Nagata, Y.; Harada, N.; Kodama, Y.; Takahashi, F.; Morio, Y.; Takahashi, K.

10.1101/584110 — physiology — Posted on 2019-03-20

1245 Inhibition of Osteoblast Proliferation and Migration by Exogenous and Endogenous Formaldehyde

Teng, X.; Huang, W.; Yu, H.; Wang, P.; Li, W.; Chen, Z.; Fan, D.

10.1101/584052 — cell biology — Posted on 2019-03-20

1246 Evaluation of PicoGreen variants for use in microscopy and flow cytometry

Khatoo, M.; Yang, J.; Gee, K. R.; Gasser, S.

10.1101/584037 — cancer biology — Posted on 2019-03-20

1247 Mate choice confers direct benefits to females of Anastrepha fraterculus (Diptera: Tephritidae)

Segura, D. F.; Bachmann, G. E.; Devescovi, F.; Nussenbaum, A. L.; Milla, F. H.; Shelly, T. E.; Cladera, J. L.; Fernandez, P. C.; Vera, M. T.

10.1101/584128 — animal behavior and cognition — Posted on 2019-03-20

1248 Translation and cross-cultural adaptation to Portuguese of The Patient- And Nutrition-Derived Outcome Risk Assessment Score (PANDORA)

Lima, J. B. d.; Campos, M. B.; Ribeiro, L. S.; Taboada, M. I. S.

10.1101/584078 — pathology — Posted on 2019-03-20

1249 Detection of EGFR deletion using unique RepSeq technology

Vinayagamoorthy, T.; Qin, D.; Ye, F.; Zhong, M.

10.1101/584045 — genomics — Posted on 2019-03-20

1250 Cell cycle inhibitor Whi5 records environmental information to coordinate growth and division in yeast

Qu, Y.; Jiang, J.; Liu, X.; Wei, P.; Yang, X.; Tang, C.

10.1101/583666 — systems biology — Posted on 2019-03-20

1251 The signaling mechanism of Hcy-induced atrial fibrosis mediated by TRPC3

Han, L.; Li, J.; Tang, Y.; Cheng, X.; Hong, K.; Wu, Y.

10.1101/583740 — molecular biology — Posted on 2019-03-20

1252 Tbet promotes NK cell bone marrow egress via CXCR6 expression

Cuff, A. O.; Perchet, T.; Dertschnig, S.; Golub, R.; Male, V.

10.1101/583575 — immunology — Posted on 2019-03-20

1253 Quaternary structural convergence and structural diversification of prion assemblies at the early replication stage

Igel-Egalon, A.; Lafferriere, F.; Moudjou, M.; Merzach, M.; Knapple, T.; Herzog, L.; Reine, F.; Doumic, M.; Rezaei, H.; Beringue, V.

10.1101/583781 — biochemistry — Posted on 2019-03-20

1254 NRT2.1 phosphorylation prevents root high affinity nitrate uptake activity in Arabidopsis thaliana

Jacquot, A.; Chaput, V.; Mauries, A.; Li, Z.; Tillard, P.; Fizames, C.; Bonillo, P.; Bellegarde, F.; Laugier, E.; Santoni, V.; Hem, S.; Martin, A.; Gojon, A.; Schulze, W.; Lejay, L.

10.1101/583542 — plant biology — Posted on 2019-03-20

1255 Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan.

de Lombares, C.; Heude, E.; Alfama, G.; Fontaine, A.; Hassouna, R.; Vernochet, C.; de Chaumont, F.; Olivo-Marin, J.-C.; Ey, E.; Parnaudeau, S.; Tronche, F.; Bourgeron, T.; Luquet, S.; Levi, G.; Narboux-Neme, N.

10.1101/583708 — physiology — Posted on 2019-03-20

1256 Interleukin 17 and senescence regulate the foreign body response

Chung, L.; Maestas, D.; Lebid, A.; Mageau, A.; Rosson, G. D.; Wu, X.; Wolf, M. T.; Tam, A.; Wang, X.; Vanderzee, I.; Andorko, J. I.; Narain, R.; Sadlter, K.; Fan, H.; Cihakova, D.; Jourdan Le Saux, C.; Housseau, F.; Pardoll, D.; Elisseeff, J.

10.1101/583757 — immunology — Posted on 2019-03-20

1257 Optimizing the power to identify the genetic basis of complex traits with Evolve and Resequence studies

Vlachos, C.; Kofler, R.

10.1101/583682 — evolutionary biology — Posted on 2019-03-20

1258 A significant role for the circadian clock in the long-term water use efficiency of Arabidopsis

Simon, N. M.; Comben, N. E.; Hetherington, A. M.; Dodd, A.

10.1101/583526 — plant biology — Posted on 2019-03-20

1259 An evaluation of pool-sequencing transcriptome-based exon capture for population genomics of non-model species

Deleury, E.; Guillemaud, T.; Blin, A.; Lombaert, E.

10.1101/583534 — genomics — Posted on 2019-03-20

1260 Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

Buschle, A.; Mrozek-Gorska, P.; Krebs, S.; Blum, H.; Cernilogar, F. M.; Schotta, G.; Pich, D.; Straub, T.; Hammerschmidt, W.

10.1101/573659 — cell biology — Posted on 2019-03-20

1261 Modular actin nano-architecture enables podosome protrusion and mechanosensing

van den Dries, K.; Nahidiazar, L.; Slotman, J. A.; Meddens, M. B. M.; Pandzic, E.; Joosten, B.; Ansems, M.; Schouwstra, J.; Meijer, A.; Steen, R.; Wijers, M.; Fransen, J.; Houtsmuller, A. B.; Wiseman, P. W.; Jalink, K.; Cambi, A.

10.1101/583492 — cell biology — Posted on 2019-03-20

1262 A stochastic hybrid model for DNA replication incorporating protein mobility dynamics

Windhager, J.; Paine, A.; Nathanailidou, P.; Tasiudi, E.; Rodriguez Martinez, M.; Lygerou, Z.; Lygeros, J.; Rapsomaniki, M. A.

10.1101/583187 — bioinformatics — Posted on 2019-03-20

1263 Engineering strategy and vector library for the rapid generation of modular light-controlled protein-protein interactions

Tichy, A.-M.; Gerrard, E. J.; Legrand, J. M. D.; Hobbs, R. M.; Janovjak, H.

10.1101/583369 — synthetic biology — Posted on 2019-03-20

1264 Knowledge and attitudes among life scientists towards reproducibility within journal articles.

Kaimaklioti Samota, E.; P. Davey, R.

10.1101/581033 — scientific communication and education — Posted on 2019-03-20

1265 A regulatory RNA is associated to invasive meningococcal disease in Europe

Karlsson, J.; Eichner, H.; Jacobsson, S.; Loh, E.

10.1101/583476 — microbiology — Posted on 2019-03-20

1266 Efferocytosis perpetuates substance accumulation inside macrophage populations

Ford, H. Z.; Zeboudj, L.; Purvis, G. S. D.; ten Bokum, A.; Zarebski, A. E.; Bull, J. A.; Byrne, H. M.; Myerscough, M. R.; Greaves, D. R.

10.1101/583484 — immunology — Posted on 2019-03-20

1267 Familial influences on Neuroticism and Education in the UK Biobank

Cheesman, R.; Coleman, J.; Rayner, C.; Purves, K. L.; Morneau-Vaillancourt, G.; Glanville, K.; Choi, S. W.; Breen, G.; Eley, T.

10.1101/582627 — genomics — Posted on 2019-03-20

1268 Genetic association study of psychotic experiences in UK Biobank

Legge, S. E.; Jones, H. J.; Kendall, K. M.; Pardinas, A. F.; Menzies, G.; Bracher-Smith, M.; Escott-Price, V.; Rees, E.; Davis, K. A. S.; Hotopf, M.; Savage, J. E.; Posthuma, D.; Holmans, P.; Kirov, G.; Owen, M. J.; O'Donovan, M.; Zammit, S.; Walters, J. T.

10.1101/583468 — genetics — Posted on 2019-03-20

1269 Population genomics of the facultatively asexual duckweed Spirodela polyrhiza

Ho, E.; Bartkowska, M.; Wright, S.; Agrawal, A.

10.1101/583021 — evolutionary biology — Posted on 2019-03-20

1270 Tracking trends in monarch abundances over the 20th century is currently impossible using museum records: a response to Boyle et al. (2019)

Ries, L.; Zipkin, E. F.; Guralnick, R. P.

10.1101/581801 — ecology — Posted on 2019-03-20

1271 Nuclear pores as versatile reference standards for quantitative superresolution microscopy

Thevathasan, J. V.; Kahnwald, M.; Cieslinski, K.; Hoess, P.; Peneti, S. K.; Reitberger, M.; Heid, D.; Kasuba, K. C.; Hoerner, S. J.; Li, Y.; Wu, Y.-L.; Mund, M.; Matti, U.; Pereira, P. M.; Henriques, R.; Nijmeijer-Winter, B.; Kueblbeck, M.; Jimenez Sabinina, V.; Ellenberg, J.; Ries, J.

10.1101/582668 — biophysics — Posted on 2019-03-20

1272 Neutrophil-derived extracellular vesicles: proinflammatory trails and anti-inflammatory microvesicles

Youn, Y.-J.; Shrestha, S.; Kim, J.-K.; Lee, Y.-B.; Lee, J. H.; Hur, K.; Mali, N. M.; Nam, S.-W.; Kim, S.-H.; Song, D.-K.; Jin, H. K.; Bae, J.-s.; Hong, C.-W.

10.1101/583435 — immunology — Posted on 2019-03-20

1273 Autistic traits lower the flexibility of information sampling: insights from a two-stage decision model

Lu, H.; Yi, L.; Zhang, H.

10.1101/582783 — neuroscience — Posted on 2019-03-20

1274 Differential N-end rule degradation of RIN4/NOI fragments generated by the AvrRpt2 effector protease

Goslin, K.; Eschen-Lippold, L.; Naumann, C.; Linster, E.; Sorel, M.; Klecker, M.; de Marchi, R.; Kind, A.; Wirtz, M.; Lee, J.; Dissmeyer, N.; Graciet, E.

10.1101/583054 — plant biology — Posted on 2019-03-20

1275 Non-medical prescribing policy in the United Kingdom National Health Service: systematic review and narrative synthesis

Graham-Clarke, E.; Rushton, A.; Noblet, T.; Marriott, J.

10.1101/582718 — pharmacology and toxicology — Posted on 2019-03-20

1276 Phosphatidylinositol 4,5 bisphosphate controls the cis and trans interactions of synaptotagmin 1

Nyenhuis, S. B.; Thapa, A.; Cafiso, D. S.

10.1101/582965 — neuroscience — Posted on 2019-03-20

1277 Effect of Antimicrobial Stewardship with Rapid MALDI-TOF Identification and Vitek 2 Antimicrobial Susceptibility Testing on Hospitalization Outcome

Cavalieri, S.; Kwon, S. S.; Vivekanandan, R.; Ased, S.; Carroll, C.; Anthone, J.; Schmidt, D.; Baysden, M.; Destache, C. J.

10.1101/581991 — microbiology — Posted on 2019-03-20

1278 Reductive dehalogenase gene biomarkers differentiate 1,1,1-trichloroethane from 1,1-dichloroethane dechlorination in microcosms and at a field site treated with granular ZVI and guar gum

Yang, M. I.; Previdsa, M.; Edwards, E. A.; Sleep, B. E.

10.1101/583229 — microbiology — Posted on 2019-03-20

1279 Whole genome base-wise aggregation and functional prediction for human non-coding regulatory variants

Zhang, S.; He, Y.; Liu, H.; Zhai, H.; Huang, D.; Yi, X.; Dong, X.; Wang, Z.; Zhao, K.; Zhou, Y.; Wang, J.; Yao, H.; Xu, H.; Yang, Z.; Sham, P. C.; Chen, K.; Li, M. J.

10.1101/583237 — genomics — Posted on 2019-03-20

1280 Analysis-ready datasets for insecticide resistance phenotype and genotype frequency in African malaria vectors

Moyes, C.; Wiebe, A.; Gleave, K.; Trett, A.; Hancock, P. A.; Padonou, G. G.; Mouhamadou, C. S.; Sovi, A.; Abuelmaali, S. A.; Ochomo, E.; Antonio-Nkondjio, C.; Dengela, D.; Kawada, H.; Dabire, R. K.; Donnelly, M. J.; Mbogo, C.; Fornadel, C.; Coleman, M.

10.1101/582510 — zoology — Posted on 2019-03-20

1281 Epistatic Transcription Factor Networks Differentially Modulate Arabidopsis Growth and Defense

Li, B.; Tang, M.; Caseys, C.; Nelson, A.; Zhou, M.; Zhou, X.; Brady, S.; Kliebenstein, D.

10.1101/583047 — plant biology — Posted on 2019-03-20

1282 Variations in Structural MRI Quality Impact Measures of Brain Anatomy: Relations with Age

Gilmore, A.; Buser, N. J.; Hanson, J. L.

10.1101/581876 — neuroscience — Posted on 2019-03-20

1283 Identification and classification of hubs in miRNA target gene networks in human neural stem/progenitor cells following Japanese encephalitis virus infection

Mukherjee, S.; Akbar, I.; Bhagat, R.; Hazra, B.; Bhattacharyya, A.; Seth, P.; Roy, D.; Basu, A.

10.1101/581983 — microbiology — Posted on 2019-03-20

1284 Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest

Cho, S.; Vashisth, M.; Abbas, A.; Majkut, S.; Vogel, K.; Xia, Y.; Ivanovska, I. L.; Irianto, J.; Tewari, M.; Zhu, K.; Tichy, E. D.; Mourkioti, F.; Tang, H.-Y.; Greenberg, R.; Prosser, B. L.; Discher, D. E.

10.1101/583179 — cell biology — Posted on 2019-03-20

1285 MM-MRE: a new technique to quantify individual muscle forces during isometric tasks of the wrist using MR elastography

Zonnino, A.; Smith, D. R.; Delgorio, P. L.; Johnson, C. L.; Sergi, F.

10.1101/582825 — bioengineering — Posted on 2019-03-20

1286 Dissecting the cognitive phenotype of post-stroke fatigue using drift diffusion modeling of sustained attention

Ulrichsen, K. M.; Alnaes, D.; Kolskaar, K. K.; Richard, G.; Sanders, A.-M.; Doerum, E. S.; Ihle-Hansen, H.; Pedersen, M. L.; Tornaas, S.; Nordvik, J. E.; Westlye, L. T.

10.1101/582502 — neuroscience — Posted on 2019-03-20

1287 Critical Variables to be Considered when Attempting to Estimate Blood Ethanol Concentrations in Rats from g/kg Exposure Data

Dannenhoffer, C. A.; Hosova, D.; Dang, S.; Dang, U.; Spear, L. P.

10.1101/582361 — neuroscience — Posted on 2019-03-20

1288 Region-specific blood-brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease

Sekhar, G. N.; Fleckney, A. L.; Boyanova, S. T.; Rupawala, H.; Lo, R.; Wang, H.; Farag, D. B.; Rahman, K. M.; Broadstock, M.; Reeves, S.; Thomas, S. A.

10.1101/582387 — neuroscience — Posted on 2019-03-20

1289 Diverse commensal E. coli clones and plasmids disseminate antimicrobial resistance genes in domestic animals and children in a semi-rural community in Ecuador

Salinas, L.; Cardenas, P. A.; Johnson, T. J.; Vasco, K.; Graham, J.; Trueba, G.

10.1101/581967 — microbiology — Posted on 2019-03-20

1290 Identifying the neural representation of fast and slow states in force field adaptation via fMRI

Farrens, A. J.; Sergi, F.

10.1101/582791 — bioengineering — Posted on 2019-03-20

1291 Individual variation in the attribution of incentive salience to social cues

Fitzpatrick, C. J.; Morrow, J. D.

10.1101/582254 — animal behavior and cognition — Posted on 2019-03-20

1292 Deletion of the creatine transporter gene in neonatal, but not adult, mice lead to cognitive deficits.

Udobi, K.; Delcimmuto, N.; Kokenge, A.; Abdulla, Z.; Perna, M.; Skelton, M.

10.1101/582320 — neuroscience — Posted on 2019-03-20

1293 Neural desynchronization and arousal differentially shape brain states for optimal sensory performance

Waschke, L.; Tune, S.; Obleser, J.

10.1101/582353 — neuroscience — Posted on 2019-03-20

1294 Rehabilitation promotes the recovery of structural and functional features of healthy neuronal networks after stroke

Allegra Mascaro, A. L.; Conti, E.; Lai, S.; Di Giovanna, A. P.; Spalletti, C.; Alia, C.; Panarese, A.; Scaglione, A.; Sacconi, L.; Micera, S.; Caleo, M.; Pavone, F. S.

10.1101/582775 — neuroscience — Posted on 2019-03-20

1295 The use of a virus-derived targeting peptide to selectively kill staphylococcus bacteria with antimicrobial peptides

Islam, S. M. A.; Choudhury, A.; Ghidey, M. R.; Kearney, C. M.

10.1101/583161 — molecular biology — Posted on 2019-03-20

1296 Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice

Lei, M.; Menon, R.; Manteiga, S.; Alden, N.; Hunt, C.; Alaniz, R. C.; Lee, K.; Jayaraman, A.

10.1101/581975 — microbiology — Posted on 2019-03-20

1297 CELL CYCLE ASYNCHRONY GENERATES DNA DAMAGE AT MITOTIC ENTRY IN POLYPLOID CELLS

Nano, M.; Simon, A.; Pennetier, C.; Fraisier, V.; Marthiens, V.; Basto, R.

10.1101/582460 — cell biology — Posted on 2019-03-20

1298 Unsupervised deep learning on biomedical data with BoltzmannMachines.jl

Lenz, S.; Hess, M.; Binder, H.

10.1101/578252 — bioinformatics — Posted on 2019-03-20

1299 The Zymoseptoria tritici ORFeome: a functional genomics community resource

Chaudhari, Y.; Cairns, T. C.; Sidhu, Y.; Attah, V.; Thomas, G.; Csukai, M.; Talbot, N. J.; Studholme, D. J.; Haynes, K.

10.1101/582205 — systems biology — Posted on 2019-03-20

1300 CRISPR-BEST: a highly efficient DSB-free base editor for filamentous actinomycetes

Tong, Y.; Robertsen, H. L.; Blin, K.; Klitgaard, A. K.; Weber, T.; Lee, S. Y.

10.1101/582403 — synthetic biology — Posted on 2019-03-20

1301 Making plants into cost-effective bioreactors for highly active antimicrobial peptides

Ghidey, M. R.; Islam, S. M. A.; Pruett, G.; Kearney, C. M.

10.1101/583146 — plant biology — Posted on 2019-03-20

1302 Dosing regimen of gentamicin and the effect of antenatal steroids on clearance in preterm infants

Santos, R. P.; Chang, Y.; Oliveira, C. R.; Adams-Huet, B.; Gard, J.; Sanchez, P. J.

10.1101/566125 — pharmacology and toxicology — Posted on 2019-03-20

1303 The Distributed Engram

Feldesh, R.

10.1101/583195 — neuroscience — Posted on 2019-03-20

1304 A Critique of Pure Learning: What Artificial Neural Networks can Learn from Animal Brains

Zador, A.

10.1101/582643 — neuroscience — Posted on 2019-03-20

1305 Assessing the role of long-noncoding RNA in nucleus accumbens in subjects with alcohol dependence

McMichael, G.; Drake, J.; Vornholt, E.; Cresswell, K.; Williamson, V.; Chatzinakos, C.; Mamdani, M.; Hariharan, S.; Kendler, K.; Miles, M.; Kalsi, G.; Riley, B.; Dozmorov, M.; Bacanu, S.-A.; Vladimirov, V.

10.1101/583203 — neuroscience — Posted on 2019-03-20

1306 Comparison of real-time PCR and droplet digital PCR for the detection of Xylella fastidiosa in plants

Dupas, E.; Legendre, B.; Olivier, V.; Poliakoff, F.; Manceau, C.; Cunty, A.

10.1101/582288 — molecular biology — Posted on 2019-03-20

1307 CRISPR/Cas9-based mutagenesis frequently provokes on-target mRNA misregulation

Tuladhar, R.; Yeu, Y.; Piazza, J. T.; Tan, Z.; Clemenceau, J. R.; Wu, X.; Barrett, Q.; Herbert, J.; Mathews, D.; Kim, J.; Hwang, T. H.; Lum, L.

10.1101/583138 — molecular biology — Posted on 2019-03-20

1308 Effect of partial selfing and polygenic selection on establishment in a new habitat

Sachdeva, H.

10.1101/582122 — evolutionary biology — Posted on 2019-03-20

1309 Protein structure without structure determination: direct coupling analysis based on in vitro evolution

Fantini, M.; Lisi, S.; de los Rios, P.; Cattaneo, A.; Pastore, A.

10.1101/582056 — evolutionary biology — Posted on 2019-03-20

1310 Training propulsion: Locomotor adaptation to accelerations of the trailing limb

Farrens, A. J.; Marbaker, R.; Lilley, M.; Sergi, F.

10.1101/582841 — bioengineering — Posted on 2019-03-20

1311 Combining gene network, metabolic, and leaf-level models show means to future-proof soybean photosynthesis under rising CO2.

Kannan, K.; Wang, Y.; Lang, M. M.; Challa, G. S.; Long, S. P.; Marshall-Colon, A.

10.1101/582981 — plant biology — Posted on 2019-03-20

1312 The menstrual cycle is a primary contributor to cyclic variation in women’s mood, behavior, and vital signs

Pierson, E.; Althoff, T.; Thomas, D.; Hillard, P.; Leskovec, J.

10.1101/583153 — physiology — Posted on 2019-03-20

1313 Comparative thermal performance of Orbicella franksi at its latitudinal range limits

Silbiger, N. J.; Goodbody-Gringley, G.; Bruno, J. F.; Putnam, H. M.

10.1101/583294 — physiology — Posted on 2019-03-20

1314 Active behaviour during early development shapes glucocorticoid reactivity

Castillo-Ramirez, L. A.; Ryu, S.; De Marco, R. J.

10.1101/582163 — physiology — Posted on 2019-03-20

1315 MitoToxy Assay: a novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic

Contreras, Y.; Ceballo, S.; Arce, R.; Sandoval, P.; Alegria, K.; Barros, F.; San Martin, A. A.

10.1101/583096 — pharmacology and toxicology — Posted on 2019-03-20

1316 Characterizing neuronal synaptic transmission using stochastic hybrid systems

Vahdat, Z.; Xu, Z.; Singh, A.

10.1101/582445 — neuroscience — Posted on 2019-03-20

1317 Neuronal histone methyltransferase EZH2 regulates neuronal morphogenesis, synaptic plasticity, and cognitive behavior of mice

Zhang, M.; Zhang, Y.; Xu, Q.; Crawford, J.; Qian, C.; Wang, G.-H.; Lewis, E.; Hall, P.; Dolen, G.; Huganir, R. L.; Qian, J.; Dong, X.; Pletnikov, M. V.; Liu, C.-M.; Zhou, F.-Q.

10.1101/582908 — neuroscience — Posted on 2019-03-20

1318 A generic deviance detection principle for cortical On/Off responses, omission response, and mismatch negativity

Chien, S.-C.; Maess, B.; Knoesche, T. R.

10.1101/582437 — neuroscience — Posted on 2019-03-20

1319 Coxiella burnetii epitope-specific T-cell responses in chronic Q fever patients

Scholzen, A.; Richard, G.; Moise, L.; Hartman, E.; Bleeker-Rovers, C. P.; Reeves, P. M.; Raju Paul, S.; Martin, W. D.; De Groot, A. S.; Poznansky, M. C.; Sluder, A. E.; Garritsen, A.

10.1101/582007 — immunology — Posted on 2019-03-20

1320 DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering

Demissie, E.; Mahajan, V.; Alsufyani, F.; Kumari, S.; Yuen, G. J.; Viswanadham, V.; Tran, J. Q.; Moon, J. J.; Irvine, D. J.; Pillai, S.

10.1101/582486 — immunology — Posted on 2019-03-20

1321 Exclusion and genomic relatedness methods for assignment of parentage using genotyping-by-sequencing data

Dodds, K. G.; McEwan, J. C.; Brauning, R.; van Stijn, T. C.; Rowe, S. J.; McEwan, K. M.; Clarke, S. M.

10.1101/582585 — genetics — Posted on 2019-03-20

1322 Sex Solves Haldane’s Dilemma

Hickey, D.; Golding, G. B.

10.1101/582536 — evolutionary biology — Posted on 2019-03-20

1323 Trans-generational effects on diapause and life-history-traits of an aphid parasitoid

Tougeron, K.; Devogel, M.; van Baaren, J.; Le Lann, C.; Hance, T.

10.1101/582932 — ecology — Posted on 2019-03-20

1324 Microfluidic Rapid and Autonomous Analytical Device (microRAAD) to Detect HIV from Whole Blood Samples

Phillips, E. A.; Moehling, T. J.; Ejendal, K. F. K.; Hoilett, O. S.; Byers, K. M.; Basing, L. A.; Jankowski, L. A.; Bennett, J. B.; Lin, L.-K.; Stanciu, L. A.; Linnes, J. C.

10.1101/582999 — bioengineering — Posted on 2019-03-20

1325 Single-stride exposure to pulse torque assistance provided by a robotic exoskeleton at the hip and knee joints

McGrath, R. L.; Sergi, F.

10.1101/582866 — bioengineering — Posted on 2019-03-20

1326 A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator

Athukoralage, J. S.; Graham, S.; Grueschow, S.; Rouillon, C.; White, M. F.

10.1101/582114 — biochemistry — Posted on 2019-03-20

1327 Composition variation of agarwood-associated microbial communities from Aquilaria sinensis

Mo, Q.; Fan, C.; Zhou, G.; Fu, H.; Wang, Y.

10.1101/583393 — plant biology — Posted on 2019-03-20

1328 Dynamic ubiquitination determines transcriptional activity of the plant immune coactivator NPR1

Skelly, M. J.; Furniss, J. J.; Grey, H. L.; Wong, K.-W.; Spoel, S. H.

10.1101/582296 — plant biology — Posted on 2019-03-20

1329 Strain- or Stress-sensing in mechanochemical patterning by the phytohormone auxin

Julien, J.-D.; Pumir, A.; Boudaoud, A.

10.1101/582551 — plant biology — Posted on 2019-03-20

1330 The TMEM106B rs1990621 protective variant is also associated with increased neuronal proportion

Li, Z.; Farias, F. G.; Dube, U.; Del Aguila, J. L. L.; Mihindukulasuriya, K. A.; Fernandez, M.-V. V.; Ibanez, L.; Budde, J. P.; Wang, F.; Lake, A. M.; Robles, Y.; Perez, J.; Yang, C.; Bradley, J.; Davenport, R.; Bergmann, K.; Benitez, B. A. A.; Dougherty, J. D.; Harari, O.; Cruchaga, C.

10.1101/583286 — neuroscience — Posted on 2019-03-20

1331 Two fiber pathways connecting amygdala and prefrontal cortex in humans and monkeys

Folloni, D.; Sallet, J.; Khrapichev, A. A.; Sibson, N. R.; Verhagen, L.; Mars, R. B.

10.1101/561811 — neuroscience — Posted on 2019-03-20

1332 StretchfMRI: a new technique to quantify the contribution of the reticular formation to long-latency responses via fMRI

Zonnino, A.; Farrens, A. J.; Ress, D.; Sergi, F.

10.1101/582692 — neuroscience — Posted on 2019-03-20

1333 Family saga: reconstructing the evolutionary history of a functionally diverse gene family reveals complexity at the genetic origins of novelty

Koludarov, I.; Jackson, T. N.; Pozzi, A.; Mikheyev, A. S.

10.1101/583344 — molecular biology — Posted on 2019-03-20

1334 Cell morphology and nucleoid dynamics in dividing D. radiodurans

Floc'h, K.; Lacroix, F.; Servant, P.; Wong, Y.-S.; Kleman, J.-P.; Bourgeois, D.; Timmins, J.

10.1101/582304 — microbiology — Posted on 2019-03-20

1335 Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts

Zhou, W.; Nielsen, J. B.; Fritsche, L. G.; LeFaive, J.; Gagliano Taliun, S. A.; Bi, W.; Gabrielsen, M. E.; Daly, M. J.; Neale, B. M.; Hveem, K.; Abecasis, G. R.; Willer, C. J.; Lee, S.

10.1101/583278 — genetics — Posted on 2019-03-20

1336 A transcription factor Abf1 facilitates ORC binding onto the Saccharomyces cerevisiae replication origin via histone acetylase Gcn5

Kohzaki, H.; Murakami, Y.

10.1101/583310 — genetics — Posted on 2019-03-20

1337 Allelopathic effect of Anogeissus pendula Edgew. and Grewia flavescens A.Juss on Desmodium species in Alwar district of Rajasthan

Prasad, R.; Yadav, A. S.

10.1101/582023 — ecology — Posted on 2019-03-20

1338 Synonymous SNP: Rare versus frequent codon can cause Phenotypic changes in the human genome

SRIVASTAV, A.

10.1101/582213 — bioinformatics — Posted on 2019-03-20

1339 Air mass source determines airborne microbial diversity at the ocean-atmosphere interface of the Great Barrier Reef marine ecosystem

Archer, S.; Lee, K.; King-Miaow, K.; Caruso, T.; Harvey, M.; Pointing, S.

10.1101/583427 — microbiology — Posted on 2019-03-20

1340 Tissue Tropism and Transmission Ecology Predict Virulence of Human RNA Viruses

Brierley, L.; Pedersen, A. B.; Woolhouse, M. E. J.

10.1101/581512 — epidemiology — Posted on 2019-03-19

1341 ZapA stabilizes FtsZ filament bundles without slowing down treadmilling dynamics

Caldas, P.; Lopez-Pelegrin, M.; Pearce, D. J. G.; Budanur, N. B.; Brugues, J.; Loose, M.

10.1101/580944 — biophysics — Posted on 2019-03-19

1342 Functional RNA Structures in the 3’UTR of Tick-Borne, Insect-Specific and No-Known-Vector Flaviviruses

Ochsenreiter, R.; Hofacker, I. L.; Wolfinger, M. T.

10.1101/565580 — bioinformatics — Posted on 2019-03-19

1343 A genetic screen using the Drosophila melanogaster TRiP RNAi collection to identify metabolic enzymes required for eye development

Tennessen, J. M.; Pletcher, R. C.; Hardman, S. L.; Intagliata, S. F.; Lawson, R. L.; Page, A.

10.1101/582940 — genetics — Posted on 2019-03-19

1344 Investigation of the validity of two Bayesian ancestral state reconstruction models for estimating Salmonella transmission during outbreaks

Bloomfield, S.; Vaughan, T.; Benschop, J.; Marshall, J.; Hayman, D.; Biggs, P.; Carter, P.; French, N.

10.1101/574087 — epidemiology — Posted on 2019-03-19

1345 A topological data analysis based classification method for multiple measurement

Riihimaki, H.; Chacholski, W.; Theorell, J.; Hillert, J.; Ramanujam, R.

10.1101/569210 — bioinformatics — Posted on 2019-03-19

1346 Translationally Controlled Tumor Protein TCTP as Peptide Vaccine against Schistosoma japonicum: an Immunoinformatics Approach

Abdalrahman, R. A.; Ahmed, S. S.; Elnaeem, M. A.; Mohammed, M. S.; Jammie, N. M.; Yousif, I. A.; Mohamed, W. H.; Nasr, S. Y.; Awad-Elkareem, M. A.; Hassan, M. A.

10.1101/466847 — bioinformatics — Posted on 2019-03-19

1347 From skylight input to behavioural output: a computational model of the insect polarised light compass

Gkanias, E.; Risse, B.; Mangan, M.; Webb, B.

10.1101/504597 — animal behavior and cognition — Posted on 2019-03-19

1348 The systemin signaling cascade as derived from phosphorylation time courses under stimulation by systemin and its inactive Thr17Ala (A17) analog

Hai Ahmad, F.; Wu, X. N.; Stintzi, A.; Schaller, A.; Schulze, W. X.

10.1101/535070 — plant biology — Posted on 2019-03-19

1349 NMDA receptors enhance the fidelity of synaptic integration

Li, C.; Baker, A. L.; Gulledge, A. T.

10.1101/566117 — neuroscience — Posted on 2019-03-19

1350 Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders

Mondo, E.; Barone, M.; Soverini, M.; D'Amico, F.; Cocchi, M.; Petrulli, C.; Mattioli, M.; Marliani, G.; Candela, M.; Accorsi, P. A.

10.1101/573865 — microbiology — Posted on 2019-03-19

1351 On the cross-population portability of gene expression prediction models

Keys, K. L.; Mak, A. C. Y.; White, M. J.; Eckalbar, W.; Dahl, A. W.; Mefford, J.; Mikhaylova, A. V.; Contreras, M. G.; Elhawary, J. R.; Eng, C.; Hu, D.; Huntsman, S.; Oh, S. S.; Salazar, S.; Lenoir, M. A.; Ye, C. J.; Thornton, T. A.; Zaitlen, N.; Burchard, E. G.; Gignoux, C. R.

10.1101/552042 — genomics — Posted on 2019-03-19

1352 Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight novel adipocyte biology

Tanigawa, Y.; Li, J.; Justesen, J. M.; Horn, H.; Aguirre, M.; DeBoever, C.; Chang, C.; Narasimhan, B.; Lage, K.; Hastie, T. J.; Park, C. Y.; Bejerano, G.; Ingelsson, E.; Rivas, M.

10.1101/442715 — genetics — Posted on 2019-03-19

1353 Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors

Cerquone Perpetuini, A.; Reggio, A.; Cerretani, M.; Giuliani, G.; Santoriello, M.; Stefanelli, R.; Palma, A.; Harper, S.; Castagnoli, L.; Bresciani, A.; Cesareni, G.

10.1101/581363 — cell biology — Posted on 2019-03-19

1354 Life history recorded in the vagino-cervical microbiome

Jie, Z.; Chen, C.; Hao, L.; Li, F.; Tian, L.; Tong, X.; Song, L.; Cai, K.; Yu, X.; Li, Y.; Rao, W.; Liao, Y.; Zhou, D.; Qiu, X.; Chen, X.; Zi, J.; Liu, N.; Zhang, W.; Liu, X.; Xiao, L.; Xu, X.; Yang, H.; Wang, J.; Hou, Y.; Kristiansen, K.; Jia, H.

10.1101/533588 — microbiology — Posted on 2019-03-19

1355 In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

Munro, S.; Gillingham, A. K.; Bertram, J.; Begum, F.

10.1101/553206 — cell biology — Posted on 2019-03-19

1356 Caterpillars on a phytochemical landscape

Forister, M. L.; Yoon, S.; Philbin, C. S.; Dodson, C. D.; Hart, B.; Harrison, J. G.; Shelef, O.; Fordyce, J. A.; Marion, Z. H.; Nice, C. C.; Richards, L. A.; Buerkle, C. A.; Gompert, Z.

10.1101/498139 — ecology — Posted on 2019-03-19

1357 Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

Graziano, B. R.; Town, J. P.; Nagy, T. L.; Fosnaric, M.; Penic, S.; Iglic, A.; Kralj-Iglic, V.; Gov, N.; Diz-Munoz, A.; Weiner, O. D.

10.1101/457119 — cell biology — Posted on 2019-03-19

1358 Interactions of nuclear transport factors and surface-conjugated FG nucleoporins: Insights and limitations

Hayama, R.; Sorci, M.; Keating, J. J.; Hecht, L. M.; Plawsky, J. L.; Belfort, G.; Chait, B. T.; Rout, M. P.

10.1101/435651 — biophysics — Posted on 2019-03-19

1359 Effect of temperature and photoperiod on survival and biomarkers of senescence in common woodlouse

DEPEUX, C.; SAMBA-LOUAKA, A.; BRAQUART-VARNIER, C.; MOREAU, J.; LEMAITRE, J.-F.; LAVERRE, T.; PAULHAC, H.; DECHAUME-MONCHARMONT, F.-X.; GAILLARD, J.-M.; BELTRAN-BECH, S.

10.1101/433011 — evolutionary biology — Posted on 2019-03-19

1360 Stimulus-responsive self-assembly of protein-based fractals by computational design

Hernandez, N.; Hansen, W.; Zhu, D.; Shea, M.; Khalid, M.; Manichev, V.; Putnis, M.; Chen, M.; Dodge, A.; Yang, L.; Banal, M.; Gustaffson, T.; Feldman, L.; Lee, S.-H.; Wackett, L.; Dai, W.; Khare, S.

10.1101/274183 — biophysics — Posted on 2019-03-19

1361 A transformation of oxygen saturation (the saturation virtual shunt) to improve clinical prediction model calibration and interpretation

Zhou, G.; Karlen, W.; Brant, R.; Wiens, M.; Kissoon, N.; Ansermino, J. M.

10.1101/391292 — bioengineering — Posted on 2019-03-19

1362 Evolution transforms pushed waves into pulled waves

Erm, P.; Phillips, B. L.

10.1101/266007 — ecology — Posted on 2019-03-19

1363 Intrinsic Disorder and Degeneracy in Molecular Scale Organization of Biological Membrane

Iyer, S. S.; Srivastava, A.

10.1101/582338 — biophysics — Posted on 2019-03-19

1364 The dynamics of centromere motion through the metaphase-to-anaphase transition reveal a centromere separation order

Armond, J. W.; Dale, K. L.; Burroughs, N. J.; McAinsh, A. D.; Vladimirou, E.

10.1101/582379 — cell biology — Posted on 2019-03-19

1365 ITGA2 is a target of miR-206 promoting cancer stemness and lung metastasis through enhanced ACLY and CCND1 expression in triple negative breast cancer

Adorno-Cruz, V.; Hoffmann, A. D.; Liu, X.; Wray, B.; Keri, R. A.; Liu, H.

10.1101/583062 — cancer biology — Posted on 2019-03-19

1366 Septate junctions regulate gut homeostasis through regulation of stem cell proliferation and enterocyte behavior in Drosophila

Izumi, Y.; Furuse, K.; Furuse, M.

10.1101/582148 — cell biology — Posted on 2019-03-19

1367 Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis

Bosmani, C.; Bach, F.; Leuba, F.; Hanna, N.; Burdet, F.; Pagni, M.; Hagedorn, M.; Soldati, T.

10.1101/582049 — cell biology — Posted on 2019-03-19

1368 Continuous dynamic modeling of regulated cell adhesion

Ko, J. M.; Lobo, D.

10.1101/582429 — biophysics — Posted on 2019-03-19

1369 Geographic variation in reproductive assurance of Clarkia pulchella

Bontrager, M.; Muir, C. D.; Angert, A.

10.1101/372375 — ecology — Posted on 2019-03-19

1370 A Systematic Evaluation of Single Cell RNA-Seq Analysis Pipelines

Vieth, B.; Parekh, S.; Ziegenhain, C.; Enard, W.; Hellmann, I.

10.1101/583013 — bioinformatics — Posted on 2019-03-19

1371 ganon: continuously up-to-date with database growth for precise short read classification in metagenomics

Piro, V. C.; Dadi, T. H.; Seiler, E.; Reinert, K.; Renard, B. Y.

10.1101/406017 — bioinformatics — Posted on 2019-03-19

1372 HaploBlocker: Creation of subgroup specific haplotype blocks and libraries

Pook, T.; Schlather, M.; de los Campos, G.; Mayer, M.; Schoen, C. C.; Simianer, H.

10.1101/339788 — genetics — Posted on 2019-03-19

1373 Ndr/Lats kinases bind specific Mob-family coactivators through a conserved and modular interface

Parker, B.; Gogl, G.; Balint, M.; Hetenyi, C.; Remenyi, A.; Weiss, E.

10.1101/242115 — biochemistry — Posted on 2019-03-19

1374 The human proteome co-regulation map reveals functional relationships between proteins

Kustatscher, G.; Grabowski, P.; Schrader, T.; Passmore, J. B.; Schrader, M.; Rappsilber, J.

10.1101/582247 — systems biology — Posted on 2019-03-19

1375 Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish

Chhabria, K.; Vouros, A.; Gray, C.; MacDonald, R. B.; Jiang, Z.; Wilkinson, R. N.; Plant, K.; Vasilaki, E.; Howarth, C.; Chico, T.

10.1101/576942 — neuroscience — Posted on 2019-03-19

1376 Short-term effects of sound localization training in virtual reality

Steadman, M. A.; Kim, C.; Lestang, J.-H.; Goodman, D. F. M.; Picinali, L.

10.1101/207753 — neuroscience — Posted on 2019-03-19

1377 Direct visualization of single nuclear pore complex proteins using genetically-encoded probes for DNA-PAINT

Schlichthaerle, T.; Strauss, M. T.; Schueder, F.; Auer, A.; Nijmeijer, B.; Kueblbeck, M.; Jimenez Sabinina, V.; Ries, J.; Ellenberg, J.; Jungmann, R.

10.1101/579961 — cell biology — Posted on 2019-03-19

1378 Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and the potential for differential clinical activity

Hafner, M.; Mills, C. E.; Subramanian, K.; Chen, C.; Chung, M.; Boswell, S. A.; Everley, R. A.; Liu, C.; Walmsley, C. S.; Juric, D.; Sorger, P.

10.1101/211680 — cancer biology — Posted on 2019-03-19

1379 Post-transcriptional mechanisms distinguish human and chimp forebrain progenitor cells

Grassi, D.; Brattaas, P. L.; Valdes, J. G.; Rezeli, M.; Jonsson, M. E.; Nolbrant, S.; Parmar, M.; Marko-Varga, G.; Jakobsson, J.

10.1101/582197 — neuroscience — Posted on 2019-03-19

1380 A stable pollination environment limits current but not potential evolution of floral traits

Castellanos, M. C.; Montero-Pau, J.; Ziarsolo, P.; Blanca, J. M.; Canizares, J.; Pausas, J. G.

10.1101/581827 — evolutionary biology — Posted on 2019-03-19

1381 Integrative network modeling reveals mechanisms underlying T cell exhaustion

Bolouri, H.; Young, M.; Beilke, J.; Johnson, R.; Fox, B.; Huang, L.; Costa Santini, C.; Hill, C. M.; van der Vuurst de Vries, A.-R.; Shannon, P.; Dervan, A.; Sivakumar, P.; Trotter, M.; Bassett, D.; Ratushny, A.

10.1101/582312 — systems biology — Posted on 2019-03-19

1382 crAssphage abundance and genomic selective pressure correlate with altered bacterial abundance in the fecal microbiota of South African mother-infant dyads

Brown, B. P.; Wendoh, J.; Chopera, D.; Havyarimana, E.; Jaumdally, S. Z.; Nyangahu, D. D.; Gray, C.; Martin, D. P.; Varsani, A.; Jaspan, H. B.

10.1101/582015 — microbiology — Posted on 2019-03-19

1383 Cross-transmission is not the source of new Mycobacteirum abscessus infections in a multi-centre cohort of cystic fibrosis patients

Doyle, R. M.; Rubio, M.; Dixon, G.; Hartley, J.; Klein, N.; Coll, P.; Harris, K. A.

10.1101/582684 — microbiology — Posted on 2019-03-19

1384 A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression

Burgess, S. T.; Marr, E. J.; Bartley, K.; Nunn, F. G.; Down, R. E.; Weaver, R. J.; Prickett, J. C.; Dunn, J.; Rombauts, S.; Van Leeuwen, T.; Van de Peer, Y.; Nisbet, A. J.

10.1101/578120 — genomics — Posted on 2019-03-19

1385 On triangular inequalities of correlation-based distances for gene expression profiles

Jiaxing, C.; Ng, Y. K.; Lin, L.; Jiang, Y.; Li, S.

10.1101/582106 — bioinformatics — Posted on 2019-03-19

1386 Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35

Huckins, L. M.; Breen, M. S.; Chatzinakos, C.; Hartmann, J.; Klengel, T.; da Silva Almeida, A. C.; Dobbyn, A.; Girdhar, K.; Hoffman, G. E.; Klengel, C.; Logue, M.; Lori, A.; Morrison, F. G.; Nguyen, H. T.; Park, Y.; Ruderfer, D.; Sloofman, L.; van Rooij, S. J.; PTSD Working Group of the Psychiatric Genomics Con, ; Baker, D.; Chen, C.-Y.; Cox, N.; Duncan, L.; Geyer, M. A.; Glatt, S.; Im, H. K.; Maihofer, A.; Risbrough, V. B.; Smoller, J. W.; Stein, D. J.; Yehuda, R.; Liberzon, I.; Koenen, K. C.; Jovanovic, T.; Kellis, M.; Miller, M. W.; Bacanu, S.-A.; Nievergelt, C.; Buxbaum, J. D.; Sklar, P.;

10.1101/581124 — genetics — Posted on 2019-03-19

1387 Butterfly assemblages from Amazonian flooded forests are not more species-poor than from unflooded forests

Rabelo, R. M.; Magnusson, W. E.

10.1101/582742 — ecology — Posted on 2019-03-19

1388 The spindle assembly checkpoint functions during early development in non-chordate embryos.

Chenevert, J.; Roca, M.; Besnardeau, L.; Ruggiero, A.; Nabi, D.; McDougall, A.; Copley, R. R.; Christians, E.; Castagnetti, S.

10.1101/582759 — cell biology — Posted on 2019-03-19

1389 LF4/MOK and a CDK-related kinase regulate the number and length of cilia in Tetrahymena

Jiang, Y.-Y.; Maier, W.; Baumeister, R.; Minevich, G.; Joachimiak, E.; Wloga, D.; Ruan, Z.; Kannan, N.; Bocarro, S.; Bahraini, A.; Vasudevan, K. K.; Lechtreck, K.; Orias, E.; Gaertig, J.

10.1101/582833 — cell biology — Posted on 2019-03-19

1390 Towards a fully automated surveillance of well-being status in laboratory mice using deep learning

Andresen, N.; Wöllhaf, M.; Hohlbaum, K.; Lewejohann, L.; Hellwich, O.; Thöne-Reineke, C.; Belik, V.

10.1101/582817 — animal behavior and cognition — Posted on 2019-03-19

1391 A quantitative modular modeling approach reveals the consequences of different A20 feedback implementations for the NF-kB signaling dynamics

Mothes, J.; Ipenberg, I.; Arslan, S. C.; Benary, U.; Scheidereit, C.; Wolf, J.

10.1101/582767 — systems biology — Posted on 2019-03-19

1392 An event-related potential study of decision making and feedback utilization in female college students who binge drink

Na, E.-C.; Jang, K.-M.; Kim, M.-S.

10.1101/582734 — neuroscience — Posted on 2019-03-19

1393 Relation of seasonal birth pulses and maternal immunity with viral invasion and persistence: A case study of Hendra virus infection in a population of black flying foxes (Pteropus alecto)

Jeong, J.; Peel, A. J.; Plowright, R. K.; Restif, O.; McCallum, H.

10.1101/582726 — epidemiology — Posted on 2019-03-19

1394 Novel insights into the morphology of Plesiochelys bigleri from the early Kimmeridgian of Northwestern Switzerland

Burek - Raselli, I. J.; Anquetin, J.

10.1101/582700 — paleontology — Posted on 2019-03-19

1395 Ribosome profiling at isoform level reveals an evolutionary conserved impact of differential splicing on the proteome

Reixachs-Sole, M.; Ruiz-Orera, J.; Alba, M.; Eyras, E.

10.1101/582031 — genomics — Posted on 2019-03-19

1396 Determinants of transcription factor regulatory range

Chen, C.-H.; Zheng, R.; Fan, J.; Brown, M.; Liu, J. S.; Meyer, C. A.; Liu, X. S.

10.1101/582270 — genomics — Posted on 2019-03-19

1397 Droplet scRNA-seq is not zero-inflated

Svensson, V.

10.1101/582064 — bioinformatics — Posted on 2019-03-19

1398 REMI-seq: Development of methods and resources for functional genomics in Dictyostelium

Gruenheit, N.; Baldwin, A.; Stewart, B.; Jaques, S.; Keller, T.; Parkinson, K.; Chisholm, R.; Harwood, A.; Thompson, C.

10.1101/582072 — genomics — Posted on 2019-03-19

1399 An ATAC-seq atlas of chromatin accessibility in mouse tissues

Liu, C.; Wang, M.; Wei, X.; Wu, L.; Xu, J.; Dai, X.; Xia, J.; Cheng, M.; Yuan, Y.; Zhang, P.; Li, J.; Feng, T.; Chen, A.; Zhang, W.; Chen, F.; Shang, Z.; Zhang, X.; Peters, B. A.; Liu, L.

10.1101/582171 — genomics — Posted on 2019-03-19

1400 Coronary atherosclerosis: Un-altered physiology

de Groot, P.; Veldhuizen, R. W.

10.1101/581454 — pathology — Posted on 2019-03-19

1401 The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3

Kuang, Z.; Wang, Y.; Li, Y.; Ye, C.; Ruhn, K. A.; Behrendt, C. L.; Olson, E. N.; Hooper, L. V.

10.1101/580613 — microbiology — Posted on 2019-03-19

1402 Tissue Tropism and Transmission Ecology Predict Virulence of Human RNA Viruses

Brierley, L.; Pedersen, A. B.; Woolhouse, M. E. J.

10.1101/581512 — epidemiology — Posted on 2019-03-19

1403 Differences in proteome response to cold acclimation in Zoysia japonica cultivars with different levels of freeze tolerance

Brown, J. M.; Holloway, M. P.; Dacosta, M. A.; Bernstein, R. P.; Lu, J. H.; Tuong, T. D.; Patton, A. J.; Dunne, J. C.; Arellano, C.; Livingston, D. P.; Milla-Lewis, S. R.

10.1101/581488 — physiology — Posted on 2019-03-19

1404 Transitions in brain-network level information processing dynamics are driven by alterations in neural gain

Li, M.; Han, Y.; Aburn, M. J.; Breakspear, M.; Poldrack, R. A.; Shine, J. M.; Lizier, J. T.

10.1101/581538 — neuroscience — Posted on 2019-03-19

1405 Inter-individual genomic heterogeneity within European population isolates

Anagnostou, P.; Dominici, V.; Battaggia, C.; Sarno, S.; Boattini, A.; Calo, C.; Francalacci, P.; Vona, G.; Tofanelli, S.; Vilar, M.; Colonna, V.; Pagani, L.; Destro Bisol, G.

10.1101/581470 — genomics — Posted on 2019-03-19

1406 DNA methylation, microRNA expression profiles and their relationships with transcriptome in grass-fed and grain-fed Angus Cattle rumen tissue

Li, Y.; Carrillo, J. A.; Ding, Y.; He, Y.; Zhao, C.; Liu, J.; Zan, L.; Song, J.

10.1101/581421 — genomics — Posted on 2019-03-19

1407 Regulation of hippocampal memory by mTORC1 in somatostatin interneuron: Hippocampal SOM interneurons, mTORC1 and memory

Artinian, J.; Jordan, A.; Khlaifia, A.; Honore, E.; La Fontaine, A.; Racine, A.-S.; Laplante, I.; Lacaille, J.-C.

10.1101/580670 — neuroscience — Posted on 2019-03-19

1408 Greater neurodegeneration and behavioral deficits after single closed head traumatic brain injury in adolescent vs adult mice

Guilhaume-Correa, F.; Cansler, S. M.; Shalosky, E. M.; Goodman, M. D.; Evanson, N. K.

10.1101/577999 — neuroscience — Posted on 2019-03-19

1409 Vps34/PIK3C3 deletion in thyroid impairs thyroid hormonogenesis and autophagic flux

Grieco, G.; Wang, T.; Delcorte, O.; Janssens, V.; Spourquet, C.; Strickaert, A.; Gaide Chevronnay, H. P.; Liao, X.-H.; Bilanges, B.; Refetoff, S.; Vanhaesebroeck, B.; Maenhaut, C.; Courtoy, P. J.; Pierreux, C. E.

10.1101/580142 — cell biology — Posted on 2019-03-19

1410 LNISKS: Reference-free mutation identification for large and complex crop genomes

Suchecki, R.; Sandhu, A.; Deschamps, S.; Llaca, V.; Wolters, P.; Watson-Haigh, N.; Pallotta, M.; Whitford, R.; Baumann, U.

10.1101/580829 — bioinformatics — Posted on 2019-03-19

1411 Reconstruction and Analysis of a Kluyveromyces marxianus Genome-scale Metabolic Model

Marcisauskas, S.; Ji, B.; Nielsen, J.

10.1101/581587 — systems biology — Posted on 2019-03-19

1412 Biofilm-dependent evolutionary pathways to antibiotic resistance

Santos-Lopez, A.; Marshall, C. W.; Scribner, M. R.; Snyder, D.; Cooper, V. S.

10.1101/581611 — microbiology — Posted on 2019-03-19

1413 Overlapping transcriptional expression response of wheat zinc-induced facilitator-like transporters emphasize important role during Fe and Zn stress

Sharma, S.; Kaur, G.; Kumar, A.; Kaur, J.; Pandey, A. K.

10.1101/581405 — plant biology — Posted on 2019-03-19

1414 Corticolimbic circuit structure moderates an association between early life stress and later trait anxiety

Kim, M. J.; Farber, M. J.; Knodt, A. R.; Hariri, A. R.

10.1101/581926 — neuroscience — Posted on 2019-03-19

1415 Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain

Lei, M.; Tempel, W.; Liu, K.; Min, J.

10.1101/581934 — biochemistry — Posted on 2019-03-18

1416 Exploring the extracellular regulation of the tumor angiogenic interaction network using a systems biology model

Li, D.; Finley, S. D.

10.1101/581884 — systems biology — Posted on 2019-03-18

1417 Presynaptic boutons that contain mitochondria are more stable

Lees, R. M.; Johnson, J. D.; Ashby, M. C.

10.1101/580530 — neuroscience — Posted on 2019-03-18

1418 Stag1 and Stag2 regulate cell fate decisions in hematopoiesis through non-redundant topological control

Viny, A. D.; Bowman, R. L.; Liu, Y.; Lavallee, V.-P.; Redlich, S. E.; Xiao, W.; Durham, B. H.; Navitski, A.; Park, J.; Braunstein, S.; Azizi, E.; Witkin, M.; Baslan, T.; Ott, C. J.; Pe'er, D.; Dekker, J.; Koche, R.; Levine, R. L.

10.1101/581868 — cell biology — Posted on 2019-03-18

1419 Graphene nanoflakes for acute manipulation of membrane cholesterol and transmembrane signaling

Kitko, K. E.; Hong, T.; Lazarenko, R. M.; Montenegro-Burke, R. J.; Shah, A. T.; Zhang, Y.; Raghunathan, K.; Kenworthy, A. K.; Skala, M. C.; McLean, J. A.; Xu, Y.-Q.; Zhang, Q.

10.1101/581942 — cell biology — Posted on 2019-03-18

1420 The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

Prajsnar, T. K.; Serba, J. J.; Dekker, B. M.; Gibson, J. F.; Masud, S.; Fleming, A.; Johnston, S. A.; Renshaw, S. A.; Meijer, A. H.

10.1101/581223 — immunology — Posted on 2019-03-18

1421 Absolute and relative pitch processing in the human brain: Neural and behavioral evidence

Leipold, S.; Brauchli, C.; Greber, M.; Jaencke, L.

10.1101/526541 — neuroscience — Posted on 2019-03-18

1422 Dynamics of genomic change during evolutionary rescue in the seed beetle Callosobruchus maculatus

Rego, A.; Messina, F. J.; Gompert, Z.

10.1101/364158 — evolutionary biology — Posted on 2019-03-18

1423 Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons

Haq, N.; Schmidt-Hieber, C.; Sialana, F. J.; Ciani, L.; Heller, J. P.; Stewart, M.; Bentley, L.; Wells, S.; Rodenburg, R. J.; Nolan, P. M.; Forsythe, E.; Wu, M. C.; Lubec, G.; Hausser, M.; Beales, P.; Christou-Savina, S.

10.1101/580399 — cell biology — Posted on 2019-03-18

1424 Nicotinamide Deficiency In Primary Open-Angle Glaucoma

Kouassi Nzoughet, J.; Chao de la Barca, J. M.; Guehlouz, K.; Leruez, S.; Coulbault, L.; Allouche, S.; Bocca, C.; Muller, J.; Amati-Bonneau, P.; Gohier, P.; Bonneau, D.; Simard, G.; Milea, D.; Lenaers, G.; Procaccio, V.; Reynier, P.

10.1101/571638 — biochemistry — Posted on 2019-03-18

1425 Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers

Wooten, D. J.; Maddox, S. F.; Tyson, D.; Liu, Q.; Lim, J. S.; Sage, J.; Lopez, C.; Quaranta, V.

10.1101/506402 — systems biology — Posted on 2019-03-18

1426 Sodium-powered stators of the bacterial flagellar motor can generate torque in the presence of phenamil with mutations near the peptidoglycan-binding region.

Ishida, T.; Ito, R.; Clark, J.; Matzke, N. J.; Sowa, Y.; Baker, M. A.

10.1101/507533 — microbiology — Posted on 2019-03-18

1427 A map of climate change-driven natural selection in Arabidopsis thaliana

Exposito-Alonso, M.; Burbano, H. A.; Bossdorf, O.; Nielsen, R.; Weigel, D.

10.1101/321133 — evolutionary biology — Posted on 2019-03-18

1428 Macrophage Activation by a Substituted PyrimidoIndole Increases Anti-Cancer Activity

Hardie, J.; Mas-Rosario, J. A.; Ha, S.; Rizzo, E. M.; Farkas, M. E.

10.1101/581710 — pharmacology and toxicology — Posted on 2019-03-18

1429 LRRK2 modifies α-syn pathology and spread in mouse models and human neurons

Bieri, G.; Brahic, M.; Bousset, L.; Couthouis, J.; Kramer, N.; Ma, R.; Nakayama, L.; Monbureau, M.; Defensor, E.; Schuele, B.; Shamloo, M.; Melki, R.; Gitler, A. D.

10.1101/522086 — neuroscience — Posted on 2019-03-18

1430 Performance comparison of the Maxim and Sedia Limiting Antigen Avidity assays for incidence surveillance

Sempa, J. B.; Welte, A.; Busch, M. P.; Hall, J.; Hampton, D.; Keating, S. M.; Facente, S. N.; Marson, K.; Parkin, N.; Pilcher, C. D.; Murphy, G.; Grebe, E.

10.1101/572677 — epidemiology — Posted on 2019-03-18

1431 The mouse HP1 proteins are essential for preventing liver tumorigenesis

Saksouk, N.; Hajdari, S.; Pratlong, M.; Barrachina, C.; Zavoriti, A.; Sarrazin, A.; Pirot, N.; Noël, J.-Y.; Khellaf, L.; Fabbrizio, E.; Julien, E.; Cammas, F. M.

10.1101/441279 — cancer biology — Posted on 2019-03-18

1432 GraphClust2: annotation and discovery of structured RNAs with scalable and accessible integrative clustering

Miladi, M.; Sokhoyan, E.; Houwaart, T.; Heyne, S.; Costa, F.; Gruening, B.; Backofen, R.

10.1101/550335 — bioinformatics — Posted on 2019-03-18

1433 ProtCID: A tool for hypothesis generation of the structures of protein interactions

Xu, Q.; Dunbrack, R. L.

10.1101/579862 — bioinformatics — Posted on 2019-03-18

1434 Optimal control of acute myeloid leukaemia

Sharp, J.; Browning, A.; Mapder, T.; Burrage, K.; Simpson, M.

10.1101/429811 — synthetic biology — Posted on 2019-03-18

1435 Large-scale correlations between eight key double strand break related data sets over the whole human genome

Brahme, A.; Hulten, M.; Bengtsson, C.; Hultgren, A.; Zetterberg, A.

10.1101/581173 — genomics — Posted on 2019-03-18

1436 Population structure across scales facilitates coexistence and spatial heterogeneity of antibiotic-resistant infections

Krieger, M. S.; Nowak, M. A.; Hill, A. L.

10.1101/469171 — epidemiology — Posted on 2019-03-18

1437 Microtubules Regulate Spatial Localization and Availability of Insulin Granules in Pancreatic Beta Cells.

Bracey, K. M.; Ho, K.-H.; Yampolsky, D.; Gu, G.; Kaverina, I.; Holmes, W.

10.1101/581330 — cell biology — Posted on 2019-03-18

1438 Live detection of neural stem and glioblastoma cells by an oligothiophene derivative

Ilkhanizadeh, S.; Gracias, A.; Aslund, A. K.; Back, M.; Simon, R.; Rraklli, V.; Migliori, B.; Kavanagh, E.; Nelander, S.; Westermark, B.; Uhrbom, L.; Forsberg-Nilsson, K.; Teixeira, A. I.; Konradsson, P.; Uhlen, P.; Joseph, B.; Hermanson, O.; Nilsson, P. R.

10.1101/579185 — bioengineering — Posted on 2019-03-18

1439 Evolving optimum camouflage with Generative Adversarial Networks

Talas, L.; Fennell, J. G.; Kjernsmo, K.; Cuthill, I. C.; Scott-Samuel, N. E.; Baddeley, R. J.

10.1101/429092 — animal behavior and cognition — Posted on 2019-03-18

1440 Chrysin, but not the flavone backbone, decreases anxiety-like behavior in animal tests

Ponciano, L. J.; Costa, B. P.; Feitosa, L. M.; Campos, K. S.; Chaves, S. N.; Cueto-Escobedo, J.; Lima-Maximino, M. G.; Rodriguez-Landa, J. F.; Maximino, C.

10.1101/575514 — pharmacology and toxicology — Posted on 2019-03-18

1441 Single cell multi-omics analysis reveals novel roles for DNA methylation in sensory neuron injury responses

Hu, Y.; An, Q.; Fan, G.

10.1101/572446 — neuroscience — Posted on 2019-03-18

1442 Hybrid genome assembly and annotation of Danionella translucida

Kadobianskyi, M.; Schulze, L.; Schuelke, M.; Judkewitz, B.

10.1101/539692 — genomics — Posted on 2019-03-18

1443 Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression

Hafemeister, C.; Satija, R.

10.1101/576827 — genomics — Posted on 2019-03-18

1444 The relationship of body condition, superoxide dismutase and superoxide with sperm performance

Friesen, C.; de Graaf, S. P.; Olsson, M.

10.1101/556548 — evolutionary biology — Posted on 2019-03-18

1445 Distinct characteristics of genes associated with phenome-wide variation in maize (Zea mays)

Liang, Z.; Qiu, Y.; Schnable, J.

10.1101/534503 — bioinformatics — Posted on 2019-03-18

1446 Probing Neural Networks for Dynamic Switches of Communication Pathways

Finger, H.; Gast, R.; Gerloff, C.; Engel, A. K.; König, P.

10.1101/523522 — neuroscience — Posted on 2019-03-18

1447 Ancestral persistence of vestibulo-spinal reflexes in axial muscles in humans

Guillaud, E.; Faure, C.; Doat, E.; Bouyer, L.; Guehl, D.; Cazalets, J.-R.

10.1101/564617 — neuroscience — Posted on 2019-03-18

1448 The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders

Miller-Rhodes, P.; Kong, C.; Baht, G. S.; Rodriguiz, R. M.; Wetsel, W. C.; Gelbard, H. A.; Terrando, N.

10.1101/537472 — neuroscience — Posted on 2019-03-18

Baker, C.; Ebsch, C.; Lampl, I.; Rosenbaum, R.

10.1101/372607 — neuroscience — Posted on 2019-03-18

1450 Massively parallel fitness profiling reveals multiple novel enzymes in Pseudomonas putida lysine metabolism

Thompson, M. G.; Blake-Hedges, J. M.; Cruz-Morales, P.; Barajas, J. F.; Curran, S. C.; Eiben, C. B.; Harris, N. C.; Benites, V. T.; Gin, J. W.; Sharpless, W. A.; Twigg, F. F.; Skyrud, W.; Krishna, R. N.; Pereira, J. H.; Baidoo, E.; Petzold, C. J.; Adams, P. D.; Arkin, A. P.; Deutschbauer, A. M.; Keasling, J. D.

10.1101/450254 — microbiology — Posted on 2019-03-18

1451 Dominant coral bacterium Endozoicomonas acroporae metabolizes Dimethylsulfoniopropionate

Tandon, K.; Chiang, P.-W.; Lu, C.-Y.; Yang, S.-H.; Chan, Y.-F.; Wada, N.; Chen, P.-Y.; Chang, H.-Y.; Chou, M.-S.; Chen, W.-M.; Tang, S.-L.

10.1101/519546 — ecology — Posted on 2019-03-18

1452 An autonomous oscillator times and executes centriole biogenesis

Aydogan, M. G.; Steinacker, T. L.; Mofatteh, M.; Gartenmann, L.; Wainman, A.; Saurya, S.; Wong, S. S.; Zhou, F. Y.; Boemo, M. A.; Raff, J. W.

10.1101/510875 — cell biology — Posted on 2019-03-18

1453 Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors

Cerquone Perpetuini, A.; Reggio, A.; Cerretani, M.; Giuliani, G.; Santoriello, M.; Stefanelli, R.; Palma, A.; Harper, S.; Castagnoli, L.; Bresciani, A.; Cesareni, G.

10.1101/581363 — cell biology — Posted on 2019-03-18

1454 Multiplatform Biomarker Identification using a Data-driven Approach Enables Single-sample Classification

Zhang, L.; Thapa, I.; Haas, C.; Bastola, D.

10.1101/581686 — bioinformatics — Posted on 2019-03-18

1455 Isolating the key factors defining the magnitude of hippocampal neurogenesis’ effects on anxiety, memory and pattern separation

Franca, T. F. A.

10.1101/563023 — neuroscience — Posted on 2019-03-18

1456 Transfer of Xanthomonas campestris pv. arecae, and Xanthomonas campestris pv. musacearum to Xanthomonas vasicola (Vauterin) as Xanthomonas vasicola pv. arecae comb. nov., and Xanthomonas vasicola pv. musacearum comb. nov. and description of Xanthomonas vasicola pv. vasculorum pv. nov.

10.1101/571166 — microbiology — Posted on 2019-03-18

1457 Alveolar macrophages up-regulate a non-classical innate response to Mycobacterium tuberculosis infection in vivo

Rothchild, A. C.; Olson, G. S.; Nemeth, J.; Amon, L. M.; Mai, D.; Gold, E. S.; Diercks, A. H.; Aderem, A.

10.1101/520791 — immunology — Posted on 2019-03-18

1458 Optimising colour for camouflage and visibility using deep learning: the effects of the environment and the observer’s visual system

Fennell, J.; Talas, L.; Baddeley, R.; Cuthill, I.; Scott-Samuel, N.

10.1101/428193 — animal behavior and cognition — Posted on 2019-03-18

1459 Limits on visual awareness of object targets in the context of other object category masks: Investigating bottlenecks in the continuous flash suppression paradigm with hand and tool stimuli

Zopf, R.; Schweinberger, S. R.; Rich, A. N.

10.1101/363515 — neuroscience — Posted on 2019-03-18

1460 CRUMBLER: A tool for the Prediction of Ancestry in Cattle

Crum, T. E.; Schnabel, R. D.; Decker, J. E.; Regitano, L. C.; Taylor, J. F.

10.1101/396341 — genomics — Posted on 2019-03-18

1461 Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

Wu, Y.; Qi, T.; Wang, H.; Zhang, F.; Zheng, Z.; Phillips-Cremins, J. E.; Deary, I. J.; McRae, A. F.; Wray, N. R.; Zeng, J.; Yang, J.

10.1101/580993 — genetics — Posted on 2019-03-18

1462 Interpreting HIV Diagnostic Histories into Infection Time Estimates: Analytical Framework and Online Tool

Grebe, E.; Facente, S. N.; Bingham, J.; Pilcher, C. D.; Powrie, A.; Gerber, J.; Priede, G.; Chibawara, T.; Busch, M. P.; Murphy, G.; Kassanjee, R.; Welte, A.

10.1101/323808 — epidemiology — Posted on 2019-03-18

1463 Improving management strategies of plant diseases using sequential sensitivity analyses

Rimbaud, L.; Dallot, S.; Bruchou, C.; Thoyer, S.; Jacquot, E.; Soubeyrand, S.; Thebaud, G.

10.1101/315747 — epidemiology — Posted on 2019-03-18

1464 Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress

Chakraborty, D.; Felzen, V.; Hiebel, C.; Stuerner, E.; Perumal, N.; Manicam, C.; Sehn, E.; Grus, F.; Wolfrum, U.; Behl, C.

10.1101/580977 — cell biology — Posted on 2019-03-18

1465 Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 35-day timeline with Dexamethasone exposure.

Robinson, J.; Turkington, S.; Abey, S.; Kenea, N.; Henderson, W.

10.1101/355552 — cell biology — Posted on 2019-03-18

1466 Determining the Hierarchical Architecture of the Human Brain Using Subject-Level Clustering of Functional Networks

Akiki, T. J.; Abdallah, C. G.

10.1101/350462 — neuroscience — Posted on 2019-03-18

1467 Statistical context dictates the relationship between feedback-related EEG signals and learning

Nassar, M.; Bruckner, R.; Frank, M. J.

10.1101/581744 — neuroscience — Posted on 2019-03-18

1468 Immune profiling in M. tuberculosis infection enables stratification of patients with active disease

Duffy, D.; Nemes, E.; Llibre, A.; Rouilly, V.; Filander, E.; Africa, H.; Mabwe, S.; Jaxa, L.; Charbit, B.; Musvosvi, M.; Mulenga, H.; The Milieu Interieur Consortium, ; Thomas, S.; Hatherill, M.; Bilek, N.; Scriba, T. J.; Albert, M. L.

10.1101/581298 — immunology — Posted on 2019-03-18

1469 Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments

Gresham, D.; Bonneau, R.; Jackson, C. A.; Castro, D. M.; Saldi, G.-A.

10.1101/581678 — genomics — Posted on 2019-03-18

1470 Generalists versus specialists in fluctuating environments: a bet-hedging perspective

Haaland, T. R.; Wright, J.; Ratikainen, I. I.

10.1101/581371 — evolutionary biology — Posted on 2019-03-18

1471 Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells

Sarkar, T. J.; Quarta, M.; Mukherjee, S.; Colville, A.; Paine, P.; Doan, L.; Tran, C. M.; Chu, C. R.; Horvath, S.; Bhutani, N.; Rando, T. A.; Sebastiano, V.

10.1101/573386 — cell biology — Posted on 2019-03-18

1472 Insight into dynamics of APOBEC3G protein in complexes with DNA assessed by high speed AFM

Pan, Y.; Shlyakhtenko, L.; Lyubchenko, Y.

10.1101/581793 — biophysics — Posted on 2019-03-18

1473 Rational nanotoolbox with theranostic potential for medicated pro-regenerative corneal implants

Patra, H. K.; Azharuddin, M.; Islam, M. M.; Papapavlou, G.; Deb, S.; Zhu, G. H.; Romu, T.; Dhara, A. K.; Jafari, M. J.; Gadheri, A.; Hinkula, J.; Rajan, M. S.; Slater, N.

10.1101/581090 — biochemistry — Posted on 2019-03-18

1474 Consequences Of NMDA Receptor Deficiency Can Be Rescued In The Adult Brain

Mielnik, C. A.; Binko, M. A.; Islam, R.; Johansson, E. M.; Funk, A. J.; Chen, Y.; Milenkovic, M.; Horsfall, W.; Ross, R. A.; Groc, L.; Salahpour, A.; McCullumsmith, R. E.; Lambe, E. K.; Ramsey, A. J.

10.1101/140343 — neuroscience — Posted on 2019-03-18

1475 Host-pathogen transcriptomics of macrophages, Mucorales and their endosymbionts: a polymicrobial pas de trois

Sephton-Clark, P.; Itabangi, H.; Munoz, J. F.; Voelz, K.; Cuomo, C.; Ballou, E.

10.1101/580746 — microbiology — Posted on 2019-03-18

1476 Pan-GWAS of Streptococcus agalactiae highlights lineage specific genes associated with virulence and niche adaptation

Gori, A.; Harrison, O.; Mlia, E.; Nishihara, Y.; Chinkwita-Phiri, J.; Mallewa, M.; Dube, Q.; Swarthout, T. D.; Nobbs, A. H.; Maiden, M.; French, N.; Heyderman, R. S.

10.1101/574152 — genomics — Posted on 2019-03-18

1477 CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics

Guo, C.; Kong, W.; Kamimoto, K.; Rivera Gonzalez, G. C. C.; Yang, X.; Kirita, Y.; Morris, S. A.

10.1101/335547 — genomics — Posted on 2019-03-18

1478 Insight into the genetic aetiology of retinal detachment by combining small clinical and large population-based datasets

Boutin, T. S.; Charteris, D. G.; Chandra, A.; Campbell, S.; Hayward, C.; Campbell, A.; UK Biobank Eye & Vision Consortium, ; Nandakumar, P.; Hinds, D.; 23andMe Research Team, ; Mitry, D.; Vitart, V.

10.1101/581165 — genetics — Posted on 2019-03-18

1479 Estimating narrow-sense heritability from genome-wide data in admixed populations

Athanasiadis, G.; Speed, D.; Andersen, M. K.; Appel, E. V. R.; Grarup, N.; Brandslund, I.; Joergensen, M. E.; Larsen, C. V. L.; Bjerregaard, P.; Hansen, T.; Albrechtsen, A.

10.1101/581389 — genetics — Posted on 2019-03-18

1480 Labour sharing promotes coexistence in atrazine degrading bacterial communities

Billet, L.; Devers, M.; Rouard, N.; Martin-Laurent, F.; Spor, A.

10.1101/581041 — evolutionary biology — Posted on 2019-03-18

1481 Long-term reduction of short wavelength light affects sustained attention and visuospatial working memory.

Domagalik, A.; Oginska, H.; Beldzik, E.; Fafrowicz, M.; Marek, T.

10.1101/581314 — animal behavior and cognition — Posted on 2019-03-18

1482 PERK inhibition mitigates restenosis and thrombosis - a potential low-thrombogenic anti-restenotic paradigm

Wang, B.; Zhang, M.; Urabe, G.; Chen, G.; Wheeler, D.; Dornbos, D.; Huttinger, A.; Huang, Y.; Nimjee, S.; Gong, S.; Guo, L.; Kent, K. C.

10.1101/581397 — pathology — Posted on 2019-03-18

1483 Tissue mechanics controls T-cell activation and metabolism

Meng, K.; Majedi, F. S.; Thauland, T. J.; Butte, M.

10.1101/581322 — immunology — Posted on 2019-03-18

1484 Schizophrenia Polygenic Risk Score and 20-Year Course of Illness in Psychotic Disorders

Jonas, K. G.; Lencz, T.; Li, K.; Malhotra, A. K.; Perlman, G.; Fochtmann, L. J.; Bromet, E.; Kotov, R.

10.1101/581579 — genetics — Posted on 2019-03-18

1485 De novo Identification of Essential Protein Domains from CRISPR/Cas9 Tiling-sgRNA Knockout Screens

He, W.; Zhang, L.; Villarreal, O. D.; Fu, R.; Bedford, E.; Dou, J.; Bedford, M. T.; Shi, X.; Chen, T.; Bartholomew, B.; Xu, H.

10.1101/581751 — bioinformatics — Posted on 2019-03-18

1486 Sex differences in reward- and punishment-guided actions

Tara, C. G.; Wallin-Miller, K. G.; Rear, A. A.; Park, J.; Diaz, V.; Simon, N. W.; Moghaddam, B.

10.1101/581546 — animal behavior and cognition — Posted on 2019-03-18

1487 A simple model of a quadruped discovers single-foot walking and trotting as energy optimal strategies

Polet, D. T.; Bertram, J. E. A.

10.1101/580779 — zoology — Posted on 2019-03-18

1488 The mesoSPIM initiative: open-source light-sheet mesoscopes for imaging in cleared tissue

Voigt, F.; Kirschenbaum, D.; Platonova, E.; Pages, S.; Campbell, R. A. A.; Kaestli, R.; Schaettin, M.; Egolf, L.; van der Bourg, A.; Bethge, P.; Haenraets, K.; Frezel, N.; Topilko, T.; Perin, P.; Hillier, D.; Hildebrand, S.; Schueth, A.; Roebroeck, A.; Roska, B.; Stoeckli, E.; Pizzala, R.; Renier, N.; Zeilhofer, H. U.; Karayannis, T.; Ziegler, U.; Batti, L.; Holtmaat, A.; Lüscher, C.; Aguzzi, A.; Helmchen, F.

10.1101/577122 — neuroscience — Posted on 2019-03-18

1489 Integrating electric field modelling and neuroimaging to explain variability of low intensity tES effects

Kasten, F. H.; Duecker, K.; Meiser, A.; Herrmann, C. S.

10.1101/581207 — neuroscience — Posted on 2019-03-18

1490 Predicting the effects of SNPs on transcription factor binding affinity

Nishizaki, S. S.; Ng, N.; Dong, S.; Morterud, C.; Williams, C.; Boyle, A. P.

10.1101/581306 — bioinformatics — Posted on 2019-03-18

1491 Crystal structure of the LRR ectodomain of the plant immune receptor kinase SOBIR1.

Hohmann, U.; Hothorn, M.

10.1101/581231 — plant biology — Posted on 2019-03-18

1492 Molecular mechanisms for intestinal HCO3- secretion and its regulation by guanylin in seawater-acclimated eels

Takei, Y.; Wong, M. K. S.; Ando, M.

10.1101/580761 — physiology — Posted on 2019-03-18

1493 Specific oligodendrocyte populations have differential spatial distribution and susceptibility to injury

Floriddia, E. M.; Zhang, S.; van Bruggen, D.; Goncalves dos Santos, J. P.; Altinkok, M.; Foerster, S.; Tripathi, R. B.; Richardson, W. D.; Franklin, R. J. M.; Castelo-Branco, G.

10.1101/580985 — neuroscience — Posted on 2019-03-18

1494 Increased hippocampal excitability and reduced modulation in relevant neural networks underlying age-related cognitive mapping deficits

Diersch, N.; Valdes-Herrera, J. P.; Tempelmann, C.; Wolbers, T.

10.1101/581108 — neuroscience — Posted on 2019-03-18

1495 Predictive Coding beyond simple tone-based oddball designs

Vidal, Y.; Brusini, P.; Bonfieni, M.; Mehler, J.; Bekinschtein, T.

10.1101/581355 — neuroscience — Posted on 2019-03-18

1496 Schwann cell demyelination is triggered by a transient mitochondrial calcium release through Voltage Dependent Anion Channel 1

Tricaud, N.; Gautier, B.; Van Hameren, G.; Berthelot, J.; Gonzalez, S.; Chrast, R.

10.1101/581157 — neuroscience — Posted on 2019-03-18

1497 Growth Mode and Carbon Source Impact the Surfaceome Dynamics of Lactobacillus rhamnosus GG

Savijoki, K.; Nyman, T. A.; Kainulainen, V.; Miettinen, I.; Siljamäki, P.; Fallarero, A.; Sandholm, J.; Satokari, R.; Varmanen, P.

10.1101/579953 — microbiology — Posted on 2019-03-18

1498 Development of a deep amplicon sequencing method to determine the proportional species composition of piroplasm haemoprotozoa as an aid in their control

Chaudhry, U.; Ali, Q.; Rashid, I.; Shabbir, M. Z.; Abbas, M.; Numan, M.; Evans, M.; Ashraf, K.; Morrison, I.; Morrison, L.; Sargison, N. D.

10.1101/580183 — microbiology — Posted on 2019-03-18

1499 Genomic dissection of maternal, additive and non-additive genetic effects for growth and carcass traits in Nile tilapia

Joshi, R.; Woolliams, J.; Meuwissen, T.; Gjoen, H. M.

10.1101/579334 — genomics — Posted on 2019-03-18

1500 The distinct phenotypic signatures of dispersal and stress in an arthropod model: from physiology to life history

Dahirel, M.; Masier, S.; Renault, D.; Bonte, D.

10.1101/581116 — ecology — Posted on 2019-03-18

1501 A game theoretic approach to deciphering the dynamics of amyloid-β aggregation along competing pathways

Ghosh, P.; Rana, P.; Rangachari, V.; Saha, J.; Steen, E.; Vaidya, A.

10.1101/581629 — biophysics — Posted on 2019-03-18

1502 Aromatic polyketide biosynthesis: fidelity, evolution and engineering

Qin, Z.; Devine, R.; Hutchings, M. I.; Wilkinson, B.

10.1101/581074 — bioengineering — Posted on 2019-03-18

1503 KHNYN is essential for ZAP-mediated restriction of HIV-1 containing clustered CpG dinucleotides

Ficarelli, M.; Wilson, H.; Pedro Galao, R.; Neil, S.; Swanson, C. M.

10.1101/581785 — immunology — Posted on 2019-03-18

1504 PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions

Grebenova, D.; Holoubek, A.; Röselova, P.; Obr, A.; Brodska, B.; Kuzelova, K.

10.1101/580928 — cell biology — Posted on 2019-03-18

1505 Ultrasound Imaging of Gene Expression in Mammalian Cells

Farhadi, A.; Ho, G. H.; Sawyer, D. P.; Bourdeau, R. W.; Shapiro, M. G.

10.1101/580647 — bioengineering — Posted on 2019-03-18

1506 Exceptional subgenome stability and functional divergence in allotetraploid teff, the primary cereal crop in Ethiopia

VanBuren, R.; Wai, C. M.; Pardo, J.; Yocca, A. E.; Wang, X.; Wang, H.; Chaluvadi, S. R.; Bryant, D.; Edger, P. P.; Bennetzen, J. L.; Mockler, T. C.; Michael, T. P.

10.1101/580720 — plant biology — Posted on 2019-03-18

1507 Overt and covert paths for sound in the auditory system of mammals

Auriol, B. M.; Auriol, B.; Beard, J.; Bibe, B.; Broto, J.-M.; Descouens, D.; Durand, L. J.; Florens, J.-P.; Garcia, F.; Joiner, E.; Libes, B.; Pergent, P.; Ruiz, R.; Thalamas, C.

10.1101/561779 — physiology — Posted on 2019-03-18

1508 The Fruit Fly Brain Observatory: From Structure to Function

Ukani, N. H.; Yeh, C.-H.; Tomkins, A.; Zhou, Y.; Florescu, D.; Luna Ortiz, C.; Huang, Y.-C.; Wang, C.-T.; Turkcan, M. K.; Liu, T.; Richmond, P.; Lo, C.-C.; Coca, D.; Chiang, A.-S.; Lazar, A. A.

10.1101/580290 — neuroscience — Posted on 2019-03-18

1509 Atypical developmental features of cortical thickness trajectories in Autism Spectrum Disorder

Nunes, A. S.; Vakorin, V. A.; Kozhemiako, N.; Peatfield, N.; Ribary, U.; Doesburg, S.

10.1101/580837 — neuroscience — Posted on 2019-03-18

1510 Dissociable neural circuits underlie the resolution of three discrete sources of competition during task-switching.

Burke, K. M.; Molholm, S.; Butler, J. S.; Ross, L. A.; Foxe, J. J.

10.1101/581777 — neuroscience — Posted on 2019-03-18

1511 A comprehensive map of the dendritic cell transcriptional network engaged upon innate sensing of HIV

Johnson, J. S.; De Veaux, N.; Rives, A. W.; Lahaye, X.; Lucas, S. Y.; Perot, B.; Luka, M.; Amon, L. M.; Watters, A.; Aderem, A.; Manel, N.; Littman, D. R.; Bonneau, R.; Menager, M. M.

10.1101/579920 — immunology — Posted on 2019-03-18

1512 Selection and gene flow shape niche-associated copy-number variation of pheromone receptor genes

Lee, D.; Zdraljevic, S.; Cook, D. E.; Frezal, L.; Hsu, J.-C.; Sterken, M. G.; Riksen, J. A. G.; Wang, J.; Kammenga, J. E.; Braendle, C.; Felix, M.-A.; Schroeder, F. C.; Andersen, E. C.

10.1101/580803 — evolutionary biology — Posted on 2019-03-18

1513 Ring canals permit extensive cytoplasm sharing among germline cells independent of fusomes in Drosophila testes

Kaufman, R. S.; Price, K. L.; Mannix, K.; Ayers, K.; Hudson, A. M.; Cooley, L.

10.1101/581702 — developmental biology — Posted on 2019-03-18

1514 An efficient timer and sizer of biomacromolecular motions

Chan, J.; Lin, H.-R.; Takemura, K.; Chang, K.-C.; Chang, Y.-Y.; Joti, Y.; Kitao, A.; Yang, L.-W.

10.1101/384511 — biophysics — Posted on 2019-03-18

1515 The structural evolution of host-pathogen protein interactions: an integrative approach

Brito, A. F.; Pinney, J. W.

10.1101/581637 — bioinformatics — Posted on 2019-03-18

1516 Data Distribution for Phylogenetic Inference with Site Repeats via Judicious Hypergraph Partitioning

Baar, I.; Hubner, L.; Oettig, P.; Zapletal, A.; Schlag, S.; Stamatakis, A.; Morel, B.

10.1101/579318 — bioinformatics — Posted on 2019-03-18

1517 Transient upregulation of translational efficiency in prodromal Tg2576 mice precipitates AD symptoms

Borreca, A.; Valeri, F.; De Luca, M.; Ernst, L.; Russo, A.; Cordella, A.; Corsetti, V.; Nobili, A.; Amadoro, G.; Mercuri, N. B.; D'Amelio, M.; Ammassari-Teule, M.

10.1101/581652 — neuroscience — Posted on 2019-03-18

1518 Genomic analysis unveils important aspects of population structure, virulence, and antimicrobial resistance in Klebsiella aerogenes

Passarelli-Araujo, H.; Palmeiro, J. K.; Moharana, K. C.; Pedrosa-Silva, F.; Dalla-Costa, L.; Venancio, T. M.

10.1101/581645 — genomics — Posted on 2019-03-18

1519 PP2A inhibitor PME-1 suppresses anoikis, and is associated with therapy relapse of PTEN-deficient prostate cancers

Rupp, C.; Aakula, A.; Isomursu, A.; Erickson, A.; Kauko, O.; Shah, P.; Padzik, A.; Kaur, A.; Li, S.-P.; Pokharel, Y. R.; Trottman, L.; Rannikko, A.; Taimen, P.; Lammerding, J.; Paatero, I.; Mirtti, T.; Ivaska, J.; Westermarck, J.

10.1101/581660 — cancer biology — Posted on 2019-03-18

1520 Sign-tracking behavior is difficult to extinguish and resistant to multiple cognitive enhancers

Fitzpatrick, C. J.; Geary, T.; Creeden, J. F.; Morrow, J. D.

10.1101/581769 — animal behavior and cognition — Posted on 2019-03-18

1521 Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling

Renschler, G.; Richard, G.; Keller Valsecchi, C.; Toscano, S.; Arrigoni, L.; Ramirez, F.; Akhtar, A.

10.1101/580969 — genomics — Posted on 2019-03-18

1522 CGAT-core: a python framework for building scalable, reproducible computational biology workflows

Cribbs, A.; Luna-Valero, S.; George, C.; Sudbery, I. M.; Berlanga-Taylor, A. J.; Sansom, S. N.; Smith, T.; Ilott, N. E.; Johnson, J.; Scaber, J.; Brown, K.; Sims, D.; Heger, A.

10.1101/581009 — genomics — Posted on 2019-03-18

1523 T-cell activation is modulated by the 3D mechanical microenvironment

Majedi, F. S.; Hasani-Sadrabadi, M. M.; Thauland, T. J.; Song, L.; Bouchard, L.-S.; Butte, M. J.

10.1101/580886 — immunology — Posted on 2019-03-18

1524 Protein fold prediction using simulated DEER distance distributions and decay traces

del Alamo, D.; Tessmer, M.; Stein, R. A.; Feix, J. B.; Mchaourab, H. S.; Meiler, J.

10.1101/581181 — biophysics — Posted on 2019-03-18

1525 ROS accumulation and associated cell death mediates susceptibility to Alternaria brassicae in Arabidopsis accessions

Mandal, S.; Rajarammohan, S.; Kaur, J.

10.1101/581025 — plant biology — Posted on 2019-03-18

1526 Multi-omics integration of the phenome, transcriptome and genome highlights genes and pathways relevant to essential tremor

Liao, C.; Sarayloo, F.; Rochefort, D.; Houle, G.; Akcimen, F.; He, Q.; Laporte, A. D.; Spiegelman, D.; Rajput, A.; Dion, P. A.; Rouleau, G. A.

10.1101/580753 — genomics — Posted on 2019-03-18

1527 Substrate-rigidity dependent migration of an idealized twitching bacterium

Simsek, A. N.; Braeutigam, A.; Koch, M.; Shaevitz, J.; Huang, Y.; Gompper, G.; Sabass, B.

10.1101/581348 — biophysics — Posted on 2019-03-18

1528 Ultra-compliant carbon nanotube stretchable direct bladder interface

Yan, D.; Bruns, T. M.; Wu, Y.; Zimmerman, L. L.; Stephan, C.; Cameron, A. P.; Yoon, E.; Seymour, J. P.

10.1101/580902 — bioengineering — Posted on 2019-03-18

1529 The lncRNA NEAT1_1 is dispensable for normal tissue homeostasis and cancer cell growth

Adriaens, C.; Rambow, F.; Bervoets, G.; Silla, T.; Mito, M.; Chiba, T.; Hiroshi, A.; Hirose, T.; Nakagawa, S.; Jensen, T. H.; Marine, J.-C.

10.1101/574582 — molecular biology — Posted on 2019-03-18

1530 ELIMINATION OF EGFR-OVEREXPRESSING CANCER CELLS BY CD32 CHIMERIC RECEPTOR T CELLS IN COMBINATION WITH CETUXIMAB OR PANITUMUMAB

Caratelli, S.; Arriga, R.; Sconocchia, T.; Ottaviani, A.; Lanzilli, G.; Pastore, D.; Cenciarelli, C.; Venditti, A.; Del Principe, M. I.; Lauro, D.; Landoni, E.; Du, H.; Savoldo, B.; Ferrone, S.; Dotti, G.; Sconocchia, G.

10.1101/581017 — immunology — Posted on 2019-03-18

1531 Studying ecosystems with DNA metabarcoding: lessons from aquatic biomonitoring

Bush, A.; Compson, Z.; Monk, W.; Porter, T.; Steeves, R.; Emilson, E.; Gagne, N.; Hajibabaei, M.; Roy, M.; Baird, D.

10.1101/578591 — ecology — Posted on 2019-03-18

1532 How sequence alignment scores correspond to probability models

Frith, M.

10.1101/580951 — bioinformatics — Posted on 2019-03-18

1533 A Methylation Density Binary Classifier for Predicting and Optimizing the Performance of Methylation Biomarkers in Clinical Samples

Miller, B. F.; Pisanic, T. R.; Margolin, G.; Petrykowska, H. M.; Athamanolap, P.; Osei-Tutu, A.; Annunziata, C. M.; Wang, T.-H.; Elnitski, L.

10.1101/579839 — bioinformatics — Posted on 2019-03-18

1534 Coloring Single Nanoparticle Trajectory on Live Cell Membrane with its Own History: a Presuppositionless Approach

Zhao, H.; Huang, Z.; Ge, F.; Shi, X.; Bin, X.; Liao, X.; Wang, Z.; Zhang, S.; Zhang, X.; He, Y.

10.1101/580480 — biophysics — Posted on 2019-03-18

1535 ZapA stabilizes FtsZ filament bundles without slowing down treadmilling dynamics

Caldas, P.; Lopez-Pelegrin, M.; Pearce, D. J. G.; Budanur, N. B.; Brugues, J.; Loose, M.

10.1101/580944 — biophysics — Posted on 2019-03-18

1536 Luciferase-LOV BRET enables versatile and specific transcriptional readout of cellular protein-protein interactions

Kim, C. K.; Cho, K. F.; Kim, M. W.; Ting, A. Y.

10.1101/580845 — bioengineering — Posted on 2019-03-18

1537 Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy

Giroud, J.; Trebuchon, A.; Schön, D.; Marquis, P.; Liegeois-Chauvel, C.; Poeppel, D.; Morillon, B.

10.1101/581520 — neuroscience — Posted on 2019-03-18

1538 The parietal operculum preferentially encodes heat pain and not salience

Horing, B.; Sprenger, C.; Büchel, C.

10.1101/581504 — neuroscience — Posted on 2019-03-18

1539 Genetic interactions affect lung function in patients with systemic sclerosis

Tyler, A. L.; Mahoney, J. M.; Carter, G. W.

10.1101/581553 — genetics — Posted on 2019-03-18

1540 Emerging arbovirosis (Dengue, Chikungunya, Zika) in the Southeastern Mexico: influence of social and environmental determinants on knowledge and practices. A mixed method study

Causa, R.; Luque-Fernandez, M. A.; Ochoa, H.; Dor, A.; Rodriguez, F.; Solis, R.; Pacheco, A. L.

10.1101/581603 — epidemiology — Posted on 2019-03-18

1541 Homeostasis of the intervertebral disc requires regulation of STAT3 signaling by the adhesion G-protein coupled receptor ADGRG6

Liu, Z.; Easson, G.; Zhao, J.; Makki, N.; Ahituv, N.; Hilton, M.; Tang, S.; Gray, R. S.

10.1101/581595 — developmental biology — Posted on 2019-03-18

1542 Analysis of physiological noise in quantitative cardiac magnetic resonance

Jao, T.; Nayak, K.

10.1101/581496 — bioengineering — Posted on 2019-03-18

1543 Naturally Produced Lovastatin Modifies the Histology and Proteome Profile of Goat Skeletal Muscle

Leo, T. K.; Garba, S.; Danmaigoro, A.; Sazili, A. Q.; Candyrine, S. C. L.; Jahromi, M. F.; Goh, Y. M.; Ronimus, R.; Muetzel, S.; Liang, J. B.

10.1101/581439 — molecular biology — Posted on 2019-03-18

1544 Very severe anemia and one year mortality outcome after hospitalization in Tanzanian children: A prospective cohort study

Chami, N.; Hau, D. K.; Masoza, T. S.; Smart, L. R.; Kayange, N. M.; Hokororo, A.; Ambrose, E. E.; Moschovis, P. P.; Wiens, M. O.; Peck, R. N.

10.1101/581462 — epidemiology — Posted on 2019-03-18

1545 Automated segmentation of cortical layers in BigBrain reveals divergent cortical and laminar thickness gradients in sensory and motor cortices.

Wagstyl, K.; Larocque, S.; Cucurull, G.; Lepage, C.; Cohen, J. P.; Bludau, S.; Palomero-Gallagher, N.; Funck, T.; Spitzer, H.; Dicksheid, T.; Fletcher, P. C.; Romero, A.; Zilles, K.; Amunts, K.; Bengio, Y.; Evans, A. C.

10.1101/580597 — neuroscience — Posted on 2019-03-17

1546 Visualization of Loki- and Heimdallarchaeia (Asgardarchaeota) by fluorescence in situ hybridization and catalyzed reporter deposition (CARD-FISH)

Salcher, M.; Andrei, A.-S.; Bulzu, P.-A.; Keresztes, Z. G.; Banciu, H. L.; Ghai, R.

10.1101/580431 — microbiology — Posted on 2019-03-17

1547 HIV reservoir size is determined prior to ART initiation and linked to CD8 T cell activation and memory expansion

Martin, G. E.; Pace, M.; Shearer, F.; Zilber, E.; Hurst, J.; Meyerowitz, J.; Thornhill, J. P.; Lwanga, J.; Brown, H.; Robinson, N.; Hopkins, E.; Olejniczak, N.; Nwokolo, N.; Fox, J.; Fidler, S.; Willberg, C.; Frater, J.; CHERUB investigators,

10.1101/580308 — immunology — Posted on 2019-03-17

1548 Variation in phosphorus and sulfur content shapes the genetic architecture and phenotypic associations within wheat grain ionome

Fatiukha, A.; Klymiuk, V.; Peleg, Z.; Saranga, Y.; Cakmak, I.; Krugman, T.; Korol, A. B.; Fahima, T.

10.1101/580423 — genetics — Posted on 2019-03-17

1549 Static and Dynamic Functional Connectivity Analysis of Cerebrovascular Reactivity: An fMRI Study

Lewis, N.; Lu, H.; Liu, P.; Hou, X.; Damaraju, E.; Iraji, A.; Calhoun, V.

10.1101/580621 — neuroscience — Posted on 2019-03-17

1550 Enhancing DNA metabarcoding performance and applicability with bait capture enrichment and DNA from conservative ethanol

Gauthier, M.; Konecny, L.; Nguyen, A.; Elbrecht, V.; Datry, T.; Douady, C.; Lefebure, T.

10.1101/580464 — molecular biology — Posted on 2019-03-17

1551 A Sex-Specific Switch in Platelet Receptor Signaling Following Myocardial Infarction

Cameron, S. J.; Kim, B. S.; Auerbacj, D.; Sadhra, H.; Ling, F. S.; Toth, S.; Mohan, A.; Ture, S.; Goldenberg, I.; Rich, D.

10.1101/580415 — molecular biology — Posted on 2019-03-17

1552 The structure of Macrophage Expressed Gene-1, a phagolysosome immune effector that is activated upon acidification.

Pang, S. S.; Bayly-Jones, C.; Radjainia, M.; Spicer, B. A.; Law, R. H. P.; Hodel, A. W.; Ekkel, S. M.; Conroy, P. J.; Ramm, G.; Venugopal, H.; Bird, P. I.; Hoogenboom, B. W.; Voskoboinik, I.; Gambin, Y.; Sierecki, E.; Dunstone, M. A.; Whisstock, J. C.

10.1101/580712 — biochemistry — Posted on 2019-03-17

1553 Regulation of hippocampal memory by mTORC1 in somatostatin interneuron

Artinian, J.; Jordan, A.; Khlaifia, A.; Honore, E.; La Fontaine, A.; Racine, A.-S.; Laplante, I.; Lacaille, J.-C.

10.1101/580670 — neuroscience — Posted on 2019-03-17

1554 An investigation into serotonergic and environmental interventions against depression in a simulated delayed reward paradigm

Porr, B.; Trew, A.; Miller, A.

10.1101/580456 — neuroscience — Posted on 2019-03-17

1555 Synthesizing Disparate LiDAR and Satellite Datasets through Deep Learning to Generate Wall-to-Wall Forest Inventories of New England

Ayrey, E.; Hayes, D. J.; Kilbride, J. B.; Weiskittel, A. R.

10.1101/580514 — ecology — Posted on 2019-03-17

1556 Metabolic activity affects response of single cells to a nutrient switch in structured populations

Dal Co, A.; Ackermann, M.; van Vliet, S.

10.1101/580563 — systems biology — Posted on 2019-03-17

1557 Vaccine blunts fentanyl potency in male rhesus monkeys

Tenney, R. D.; Blake, S.; Bremer, P. T.; Zhou, B.; Hwang, C. S.; Poklis, J. L.; Janda, K. D.; Banks, M.

10.1101/580100 — neuroscience — Posted on 2019-03-17

1558 Task errors drive memories that improve sensorimotor adaptation.

Leow, L.-A.; Marinovic, W.; de Rugy, A.; Carroll, T. J.

10.1101/538348 — neuroscience — Posted on 2019-03-17

1559 Generation of scale-invariant sequential activity in linear recurrent networks

Liu, Y.; Howard, M. W.

10.1101/580522 — neuroscience — Posted on 2019-03-17

1560 The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3

Kuang, Z.; Wang, Y.; Li, Y.; Ye, C.; Ruhn, K. A.; Behrendt, C. L.; Olson, E. N.; Hooper, L. V.

10.1101/580613 — microbiology — Posted on 2019-03-17

1561 Shared polygenetic variation between ASD and ADHD exerts opposite association patterns with educational attainment

Verhoef, E.; Grove, J.; Shapland, C. Y.; Demontis, D.; Burgess, S.; Rai, D.; Borglum, A. D.; St Pourcain, B.

10.1101/580365 — genetics — Posted on 2019-03-17

1562 Evaluation of gene expression and phenotypic profiling data as quantitative descriptors for predicting drug targets and mechanisms of action

Lapins, M.; Spjuth, O.

10.1101/580654 — bioinformatics — Posted on 2019-03-17

1563 Rational use of Episodic and Working Memory: A Normative Account of Prospective Memory

Momennejad, I.; Norman, K. A.; Cohen, J. D.; Singh, S.; Lewis, R. L.

10.1101/580324 — animal behavior and cognition — Posted on 2019-03-17

1564 High-intensity interval training blunts exercise-induced changes in markers of mitochondrial biogenesis in human skeletal muscle

Granata, C.; Oliveira, R. S. F.; Little, J. P.; Bishop, D. J.

10.1101/580373 — physiology — Posted on 2019-03-17

1565 Bottleneck revisited: increased adaptive variation despite reduced overall genetic diversity in a rapidly adapting invader

Selechnik, D.; Richardson, M. F.; Shine, R.; DeVore, J.; Ducatez, S.; Rollins, L. A.

10.1101/557868 — evolutionary biology — Posted on 2019-03-17

1566 Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition

10.1101/580498 — cell biology — Posted on 2019-03-17

1567 PlotsOfDifferences - a web app for the quantitative comparison of unpaired data

Goedhart, J.

10.1101/578575 — scientific communication and education — Posted on 2019-03-17

1568 Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons

Haq, N.; Schmidt-Hieber, C. S.-H.; Sialana, F. J.; Ciani, L.; Heller, J. P.; Stewart, M.; Bentley, L.; Wells, S.; Rodenburg, R. J.; Nolan, P. M.; Forsythe, E.; Wu, M. C.; Lubec, G.; Hausser, M.; Beales, P.; Christou-Savina, S.

10.1101/580399 — cell biology — Posted on 2019-03-17

1569 A deep learning framework for nucleus segmentation using image style transfer

Hollandi, R.; Szkalisity, A.; Toth, T.; Tasnadi, E.; Molnar, C.; Mathe, B.; Grexa, I.; Molnar, J.; Balind, A.; Gorbe, M.; Kovacs, M.; Migh, E.; Goodman, A.; Balassa, T.; Koos, K.; Wang, W.; Bara, N.; Kovacs, F.; Paavolainen, L.; Danka, T.; Kriston, A.; Carpenter, A. E.; Smith, K.; Horvath, P.

10.1101/580605 — bioinformatics — Posted on 2019-03-17

1570 Structural basis for the delivery of activated sialic acid into Golgi for sialyation

Nji, E.; Gulati, A.; Qureshi, A. A.; Coincon, M.; Drew, D.

10.1101/580449 — biochemistry — Posted on 2019-03-17

1571 Differential and Age Dependent Expression of Specific Sialoglycans on HeLa Cells -Revealed by Direct Fluorescent Glycan Labeling

Wu, Z.; Person, A. D.; Burton, A. J.; Singh, R.; Burroughs, B.; Fryxell, D.; Tatge, T. J.; Manning, T.; Wu, G.; Swift, K.; Kalabokis, V.

10.1101/580571 — cancer biology — Posted on 2019-03-17

1572 A haplotype-aware de novo assembly of related individuals using pedigree graph

Garg, S.; Aach, J.; Li, H.; Durbin, R.; Church, G.

10.1101/580159 — bioinformatics — Posted on 2019-03-17

1573 ProtCID: A tool for hypothesis generation of the structures of protein interactions

Xu, Q.; Dunbrack, R. L.

10.1101/579862 — bioinformatics — Posted on 2019-03-17

1574 Entrainment of local synchrony reveals a causal role for high-beta right frontal oscillations in human visual consciousness

Vernet, M.; Stengel, C.; Quentin, R.; Amengual, J. L.; Valero-Cabre, A.

10.1101/574939 — neuroscience — Posted on 2019-03-17

1575 Determinants of QTL mapping power in the realized Collaborative Cross

Keele, G. R.; Crouse, W. L.; Kelada, S. N. P.; Valdar, W.

10.1101/459966 — genetics — Posted on 2019-03-17

1576 The importance of neutral over niche processes in structuring Ediacaran early animal communities

Mitchell, E. G.; Harris, S.; Kenchington, C.; Vixseboxse, P.; Roberts, L.; Dennis, A.; Clark, C.; Liu, A.; Wilby, P.

10.1101/443275 — ecology — Posted on 2019-03-17

1577 5-methoxy-N,N-dimethyltryptamine: An ego-dissolving endogenous neurochemical catalyst of creativity

Germann, C. B.

10.1101/578435 — neuroscience — Posted on 2019-03-17

1578 pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive

Choudhary, S.

10.1101/578500 — bioinformatics — Posted on 2019-03-17

1579 Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

Kelmer Sacramento, E.; Kirkpatrick, J. M.; Mazzetto, M.; Di Sanzo, S.; Caterino, C.; Sanguanini, M.; Papaevgeniou, N.; Lefaki, M.; Childs, D.; Bagnoli, S.; Terzibasi Tozzini, E.; Bartolome, A.; Romanov, N.; Baumgart, M.; Huber, W.; Chondrogianni, N.; Vendruscolo, M.; Cellerino, A.; Ori, A.

10.1101/577478 — systems biology — Posted on 2019-03-17

1580 When can we trust population trends? A method for quantifying the effects of sampling interval and duration

Wauchope, H. S.; Amano, T.; Sutherland, W. J.; Johnston, A.

10.1101/498170 — ecology — Posted on 2019-03-17

1581 Mapping drinking water and quality of life aspects in urban settings: an application of the urban exposome

Andrianou, X. D.; van der Lek, C.; Charisiadis, P.; Ioannou, S.; Fotopoulou, K. N.; Papapanagiotou, Z.; Botsaris, G.; Beumer, C.; Makris, K. C.

10.1101/401927 — epidemiology — Posted on 2019-03-17

1582 A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells

Dang, D. K.; Makena, M. R.; Llongueras, J. P.; Prasad, H.; Ko, M.; Bandral, M.; Rao, R.

10.1101/379586 — cancer biology — Posted on 2019-03-17

1583 Morphine analgesia and mu opioid receptor signaling require programed death protein 1 (PD-1)

Wang, Z.; Jiang, C.; He, Q.; Matsuda, M.; Han, Q.; Wang, K.; Bang, S.; Ji, R.-R.

10.1101/580506 — neuroscience — Posted on 2019-03-17

1584 An RNA-binding protein secreted by Listeria monocytogenes activates RIG-I signaling

Pagliuso, A.; Tham, T. N.; Allemand, E.; Robertin, S.; Dupuy, B.; Bertrand, Q.; Becavin, C.; Koutero, M.; Najburg, V.; Nahori, M.-A.; Stavru, F.; Dessen, A.; Muchard, C.; Lebreton, A.; Komarova, A. V.; Cossart, P.

10.1101/543652 — cell biology — Posted on 2019-03-17

1585 Zebrafish larvae as a model system for systematic characterization of drugs and genes in dyslipidemia and atherosclerosis

Bandaru, M. K. K.; Emmanouilidou, A.; Ranefall, P.; von der Heyde, B.; Mazzaferro, E.; Klingstroem, T.; Masiero, M.; Dethlefsen, O.; Ledin, J.; Larsson, A.; Brooke, H. L.; Wahlby, C.; Ingelsson, E.; den Hoed, M.

10.1101/502674 — genomics — Posted on 2019-03-17

1586 Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies

Park, S.; Park, S.-K.; Watanabe, N.; Hashimoto, T.; Iwatsubo, T.; Shelkovnikova, T. A.; Liebman, S. W.

10.1101/415927 — molecular biology — Posted on 2019-03-17

1587 Mendelian Randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

Porcu, E.; Rüeger, S.; Lepik, K.; eQTLGen Consortium, ; Santoni, F. A.; Reymond, A.; Kutalik, Z.

10.1101/377267 — genetics — Posted on 2019-03-17

1588 The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology

Chen, J. L.; Moss, W. N.; Spencer, A.; Zhang, P.; Childs-Disney, J. L.; Disney, M. D.

10.1101/580407 — bioinformatics — Posted on 2019-03-17

1589 The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function

Storz, J. F.; Natarajan, C.; Signore, A. V.; Witt, C. C.; McCandlish, D. M.; Stoltzfus, A.

10.1101/580175 — evolutionary biology — Posted on 2019-03-17

1590 Improving imputation quality in BEAGLE for crop and livestock data

Pook, T.; Mayer, M.; Geibel, J.; Weigend, S.; Cavero, D.; Schön, C.-C.; Simianer, H.

10.1101/577338 — genetics — Posted on 2019-03-16

1591 Toxic Benthic Filamentous Cyanobacteria in Lakes and Rivers of South-Central Quebec, Canada

Husk, B.; Nieuwenhuis, D.

10.1101/580035 — plant biology — Posted on 2019-03-16

1592 Pupillometry as an objective measure of sustained attention in young and older listeners

Zhao, S.; Bury, G.; Milne, A.; Chait, M.

10.1101/579540 — neuroscience — Posted on 2019-03-16

1593 Large-scale functional connectivity in multisensory cortex predicts performance

Hollensteiner, K. J.; Galindo-Leon, E.; Pieper, F.; Engler, G.; Nolte, G.; Engel, A. K.

10.1101/579938 — neuroscience — Posted on 2019-03-16

1594 A candidate causal variant underlying both higher intelligence and increased risk of bipolar disorder

Shen, S. Q.; Kim-Han, J. S.; Cheng, L.; Xu, D.; Gokcumen, O.; Hughes, A. E.; Myers, C. A.; Corbo, J. C.

10.1101/580258 — genetics — Posted on 2019-03-16

1595 fuNTRp: Identifying protein positions for variation driven functional tuning

Miller, M.; Vitale, D.; Rost, B.; Bromberg, Y.

10.1101/578757 — bioinformatics — Posted on 2019-03-16

1596 Virtual reality for animal navigation with camera-based optical flow tracking

Vishniakou, I.; Ploeger, P. G.; Seelig, J.

10.1101/579813 — neuroscience — Posted on 2019-03-16

1597 Nitroxide functionalized antibiotics are promising eradication agents against Staphylococcus aureus biofilms.

Verderosa, A. D.; Dhouib, R.; Fairfull-Smith, K. E.; Totsika, M.

10.1101/579896 — microbiology — Posted on 2019-03-16

1598 Identification of a novel gammaherpesvirus in Canada lynx (Lynx canadensis)

Hendrikse, L. D.; Kambli, A.; Kayko, C.; Canuti, M.; Rodrigues, B.; Stevens, B.; Vashon, J.; Lang, A. S.; Needle, D. B.; Troyer, R. M.

10.1101/579607 — microbiology — Posted on 2019-03-16

1599 Two ecotype-related long non-coding RNAs in the environmental control of root growth

Blein, T.; Balzergue, C.; Roule, T.; Gabriel, M.; Scalisi, L.; Sorin, C.; Christ, A.; Delannoy, E.; Martin-Magniette, M.-L.; Nussaume, L.; Hartmann, C.; Gautheret, D.; Desnos, T.; Crespi, M.

10.1101/579656 — plant biology — Posted on 2019-03-16

1600 Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex.

Dickinson, A.; Varcin, K. J.; Sahin, M.; Nelson, C. A.; Jeste, S. S.

10.1101/578831 — neuroscience — Posted on 2019-03-16

1601 A Musashi-Related Protein Is Essential For Gametogenesis In Arabidopsis

Moody, L. A.; Rabbinowitsch, E.; Dickinson, H. G.; Clayton, R.; Emms, D. M.; Langdale, J.

10.1101/579714 — plant biology — Posted on 2019-03-16

1602 The interaction of compliance and activation on the force-length operating range and force generating capacity of skeletal muscle

Cox, S. M.; Easton, K. L.; Sanghvi, H.; Cromie Lear, M.; Marsh, R.; Delp, S.; Rubenson, J.

10.1101/580027 — physiology — Posted on 2019-03-16

1603 Simple, biologically informed models, but not convolutional neural networks describe target detection in naturalistic images

Fruend, I.

10.1101/578633 — neuroscience — Posted on 2019-03-16

1604 Embodiment improves performance on an immersive brain computer interface in head-mounted virtual reality

Juliano, J. M.; Spicer, R.; Lefebvre, S.; Jann, K.; Ard, T.; Santarnecchi, E.; Krum, D.; Liew, S.-L.

10.1101/578682 — neuroscience — Posted on 2019-03-16

1605 Relative Concentration of Brain Iron (rcFe) Derived from Standard Functional MRI.

Colcombe, S. J.; Milham, M. P.; Mackay-Brandt, A.; Franco, A.; Castellanos, X.; Craddock, C.; Cloud, J.

10.1101/579763 — neuroscience — Posted on 2019-03-16

1606 Exploring the limitations of event-related potential measures in moving subjects. Case studies of four different technical modifications in ergometer rowing

Hill, H.

10.1101/578534 — neuroscience — Posted on 2019-03-16

1607 Manipulation of Oscillatory Phase by Transcranial Alternating Current Stimulation

Fiene, M.; Schwab, B. C.; Misselhorn, J.; Herrmann, C.; Schneider, T. R.; Engel, A. K.

10.1101/579631 — neuroscience — Posted on 2019-03-16

1608 Evidence of extensive intraspecific noncoding reshuffling in a 169-kb mitochondrial genome of a basidiomycetous fungus

Lee, H.-H.; Ke, H.-M.; Lin, C.-Y. I.; Lee, J. J.; Chung, C.-L.; Tsai, I. J.

10.1101/579870 — evolutionary biology — Posted on 2019-03-16

1609 Targeting and Vaccine Durability Are Key for Population-level Impact and Cost-Effectiveness of a Pox-Protein HIV Vaccine Regimen in South Africa

Selinger, C.; Bershteyn, A.; Dimitrov, D. T.; Adamson, B. J.; Revill, P.; Hallett, T. B.; Phillips, A.; Bekker, L.-G.; Rees, H.; Gray, G.

10.1101/459909 — epidemiology — Posted on 2019-03-16

1610 Contribution of private gardens to habitat availability, connectivity and conservation of the common pipistrelle in Paris

Mimet, A.; Kerbiriou, C.; Simon, L.; Julien, J.-F.; Raymond, R.

10.1101/579227 — ecology — Posted on 2019-03-16

1611 pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive

Choudhary, S.

10.1101/578500 — bioinformatics — Posted on 2019-03-16

1612 Constitutive differences in glucocorticoid responsiveness are related to divergent spatial information processing abilities

Huzard, D.; Vouros, A.; Monari, S.; Astori, S.; Vasilaki, E.; Sandi, C.

10.1101/579508 — animal behavior and cognition — Posted on 2019-03-16

1613 The multicellular incoherent feedforward loop motif generates spatial patterns

Rodriguez-Paton, A.; Regueira, M.; Daza-Garcia, J.

10.1101/579342 — synthetic biology — Posted on 2019-03-16

1614 LSO:Ce Inorganic Scintillators are Biocompatible with Neuronal and Circuit Function

Bartley, A. F.; Abiraman, K.; Stewart, L. T.; Hossain, M. I.; Gahan, D. M.; Kamath, A. V.; Burdette, M. K.; Andrabe, S.; Foulger, S. H.; McMahon, L. L.; Dobrunz, L. E.

10.1101/579722 — neuroscience — Posted on 2019-03-16

1615 Lithium treatment reverses irradiation-induced changes in rodent neural progenitors

Zanni, G.; Goto, S.; Gaudenzi, G.; Naidoo, V.; Levy, G.; Di Martino, E.; Dethlefsen, O.; Cedazo-Minguez, A.; Merino-Serrais, P.; Hermanson, O.; Blomgren, K.

10.1101/579235 — neuroscience — Posted on 2019-03-16

1616 Bayesian population receptive field modeling in human somatosensory cortex

Puckett, A. M.; Bollmann, S.; Junday, K.; Barth, M.; Cunnington, R.

10.1101/577981 — neuroscience — Posted on 2019-03-16

1617 Flexible representation and memory of higher-dimensional cognitive variables with grid cells

Klukas, M.; Lewis, M.; Fiete, I.

10.1101/578641 — neuroscience — Posted on 2019-03-16

1618 The speed of human social interaction perception

Isik, L.; Mynick, A.; Pantazis, D.; Kanwisher, N.

10.1101/579375 — neuroscience — Posted on 2019-03-16

1619 Multiple Cross Displacement Amplification Coupled with Gold Nanoparticles-Based Lateral Flow Biosensor for Detection of the Mobilized Colistin Resistance Gene mcr-1

Gong, L.; Liu, E.; Che, J.; Li, J.; Liu, X.; Xu, H.; Liang, J.

10.1101/579904 — molecular biology — Posted on 2019-03-16

1620 Direct interaction of PIWI and DEPS-1 is essential for piRNA function and condensate ultrastructure in Caenorhabditis elegans

Suen, K. M.; Braukmann, F.; Butler, R.; Bensaddek, D.; Akay, A.; Lin, C.-C.; Doshi, N.; Sapetschnig, A.; Lamond, A. I.; Ladbury, J. E.; Miska, E. A.

10.1101/580043 — cell biology — Posted on 2019-03-16

1621 The Work Performed By Biological Motors

Baker, J.

10.1101/580241 — biophysics — Posted on 2019-03-16

1622 Transverse sinus injections: A novel method for whole-brain vector-driven gene delivery

Hamodi, A. S.; Martinez Sabino, A.; Fitzgerald, N. D.; Crair, M. C.

10.1101/579730 — neuroscience — Posted on 2019-03-16

1623 5-methoxy-N,N-dimethyltryptamine: An ego-dissolving endogenous neurochemical catalyst of creativity

Germann, C. B.

10.1101/578435 — neuroscience — Posted on 2019-03-16

1624 Adaptation to seasonal reproduction and thermal minima-related factors drives fine-scale divergence despite gene flow in Atlantic herring populations

Fuentes-Pardo, A. P.; Bourne, C.; Singh, R.; Emond, K.; Pinkham, L.; McDermid, J. L.; Andersson, L.; Ruzzante, D. E.

10.1101/578484 — genomics — Posted on 2019-03-16

1625 Multiple genetic loci affect place learning and memory performance in Drosophila melanogaster

Williams-Simon, P. A.; Posey, C.; Mitchell, S.; Ng'oma, E.; Mrkvicka, J.; Zars, T.; King, E.

10.1101/580092 — genetics — Posted on 2019-03-16

1626 Interpreting, forecasting, and controlling feeding behaviour using high-resolution data

McGrath, T. M.; Spreckley, E.; Rodriguez, A. F.; Viscomi, C.; Alamshah, A.; Akalestou, E.; Murphy, K. G.; Jones, N. S.

10.1101/578344 — animal behavior and cognition — Posted on 2019-03-16

1627 ‘Normal’ hearing thresholds and fundamental auditory grouping processes predict difficulties with speech-in-noise perception

Holmes, E.; Griffiths, T.

10.1101/578393 — neuroscience — Posted on 2019-03-16

1628 Sleep promotes relational overlapping memories for long-term generalization

Matorina, N.; Poppenk, J.

10.1101/578492 — neuroscience — Posted on 2019-03-16

1629 Neurophysiological predictors of memory impairment in schizophrenia: decoupled slow-wave dynamics during non-REM sleep

Bartsch, U.; Simpkin, A.; Demanuele, C.; Wamsley, E.; Marston, H.; Jones, M. W.

10.1101/578039 — neuroscience — Posted on 2019-03-16

1630 Phage-Encoded LuxR-Type Receptors Responsive to Host-Produced Bacterial Quorum-Sensing Autoinducers

Silpe, J. E.; Bassler, B. L.

10.1101/577726 — microbiology — Posted on 2019-03-16

1631 Gut microbiota plasticity is correlated with sustained weight loss on a low-carb or low-fat dietary intervention

Grembi, J. A.; Nguyen, L. H.; Haggerty, T. D.; Gardner, C. D.; Holmes, S. P.; Parsonnet, J.

10.1101/580217 — microbiology — Posted on 2019-03-16

1632 Proteomic Analysis of Plasmodium Merosomes: The Link Between Liver and Blood Stages in Malaria

Shears, M. J.; Sekhar Nirujogi, R.; Swearingen, K. E.; Renuse, S.; Mishra, S.; Jaipal Reddy, P.; Moritz, R. L.; Pandey, A.; Sinnis, P.

10.1101/580266 — microbiology — Posted on 2019-03-16

1633 The actin-capping protein alpha-adducin is required for T-cell costimulation

Thauland, T. J.; Butte, M. J.

10.1101/580191 — immunology — Posted on 2019-03-16

1634 Complete genome sequence and evolution analysis of Psychrobacter sp. YP14 from Gammaridea Gastrointestinal Microbiota of Yap Trench

Wei, J.; Gao, Z.; Liu, W.; Chen, H.

10.1101/578518 — genomics — Posted on 2019-03-16

1635 Vps34/PIK3C3 deletion in thyroid impairs thyroid hormonogenesis and autophagic flux

Grieco, G.; Wang, T.; Delcorte, O.; Janssens, V.; Spourquet, C.; Strickaert, A.; Gaide-Chevronnay, H.; Liao, X.-H.; Bilanges, B.; Refetoff, S.; Vanhaesebroeck, B.; Maenhaut, C.; Courtoy, P.; Pierreux, C.

10.1101/580142 — cell biology — Posted on 2019-03-16

1636 Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

10.1101/577478 — systems biology — Posted on 2019-03-16

1637 Adenovirus serotype 26 utilises sialic acid bearing glycans as a primary cell entry receptor

Baker, A. T.; Mundy, R.; Davies, J. A.; Rizkallah, P. J.; Parker, A. L.

10.1101/580076 — microbiology — Posted on 2019-03-16

1638 Separations-Encoded Microparticles For Single-Cell Western Blotting

Gumuscu, B.; Herr, A.

10.1101/580233 — bioengineering — Posted on 2019-03-16

1639 Molecular signatures of the rediae, cercariae and adult worm stages in the complex life cycles of parasitic flatworms (Psilostomatidae, Trematoda)

Nesterenko, M.; Starunov, V.; Shchenkov, S.; Maslova, A.; Denisova, S.; Granovich, A.; Dobrovolskij, A.; Khalturin, K.

10.1101/580225 — zoology — Posted on 2019-03-16

1640 Pyridox(am)ine 5’-phosphate oxidase deficiency induces seizures in Drosophila melanogaster

Chi, W.; Iyengar, A.; Albersen, M.; Bosma, M.; Verhoeven-Duif, N. M.; Wu, C.-F.; Zhuang, X.

10.1101/580050 — neuroscience — Posted on 2019-03-16

1641 Prioritizing putatively etiological T cell epitopes across autoimmune diseases

Ogishi, M.

10.1101/580126 — immunology — Posted on 2019-03-16

1642 How phenotypic convergence arises in experimental evolution

Simoes, P.; Fragata, I.; Santos, J.; Santos, M. A.; Santos, M.; Rose, M. R.; Matos, M.

10.1101/579524 — evolutionary biology — Posted on 2019-03-16

1643 Genomic signatures of extreme body size divergence in baboons

Chiou, K. L.; Bergey, C. M.; Burrell, A. S.; Disotell, T. R.; Rogers, J.; Jolly, C. J.; Phillips-Conroy, J. E.

10.1101/578740 — evolutionary biology — Posted on 2019-03-16

1644 Male recombination produced multiple geographically restricted neo-Y chromosome haplotypes of varying ages that correlate with onset of neo-Y decay in Drosophila albomicans

Wei, K. H.-C.; Bachtrog, D.

10.1101/580118 — evolutionary biology — Posted on 2019-03-16

1645 The complete, functional and dynamic cycle of the bacterial Initiation Factor 3

Nakamoto, J. A.; Spurio, R.; Konevega, A. L.; Fabbretti, A.; Milon, P.

10.1101/579326 — biophysics — Posted on 2019-03-16

1646 The role of strigolactones in regulation of stomatal conductance and plant-pathogen interactions in Arabidopsis thaliana

Kalliola, M.; Jakobson, L.; Davidsson, P.; Pennanen, V.; Waszczak, C.; Yarmolinsky, D.; Zamora, O.; Palva, E. T.; Kariola, T.; Kollist, H.; Brosche, M.

10.1101/573873 — plant biology — Posted on 2019-03-16

1647 Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single cell resolution: a focus on aging and cancer

O'Hara, R.; Tedone, E.; Ludlow, A. T.; Huang, E.; Arosio, B.; Mari, D.; Shay, J. W.

10.1101/579789 — molecular biology — Posted on 2019-03-16

1648 Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

Holland, D.; Frei, O.; Desikan, R.; Fan, C.-C.; Shadrin, A. A.; Smeland, O. B.; Sundar, V. S.; Thompson, P.; Andreassen, O. A.; Dale, A. M.

10.1101/133132 — genomics — Posted on 2019-03-16

1649 Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders

Seidlitz, J.; Nadig, A.; Liu, S.; Bethlehem, R. A. I.; Vertes, P. E.; Morgan, S. E.; Vasa, F.; Romero-Garcia, R.; Lalonde, F. M.; Clasen, L. S.; Blumenthal, J. D.; Paquola, C.; Bernhardt, B.; Wagstyl, K.; Polioudakis, D.; de la Torre-Ubieta, L.; Geschwind, D. H.; Han, J. C.; Lee, N. R.; Murphy, D. G.; Bullmore, E. T.; Raznahan, A.

10.1101/573279 — neuroscience — Posted on 2019-03-16

1650 Chromatin arranges in filaments of blobs with nanoscale functional zonation

Miron, E.; Oldenkamp, R.; Pinto, D. M.; Brown, J. M.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Buckle, V.; Schermelleh, L.

10.1101/566638 — genomics — Posted on 2019-03-16

1651 Spatial integration of mechanical forces by alpha-actinin establishes actin network symmetry.

Senger, F.; Pitaval, A.; Ennomani, H.; Kurzawa, L.; Blanchoin, L.; Thery, M.

10.1101/578799 — cell biology — Posted on 2019-03-16

1652 Synchronization of sensory gamma oscillations promotes multisensory communication

Misselhorn, J.; Schwab, B. C.; Schneider, T. R.; Engel, A. K.

10.1101/523688 — neuroscience — Posted on 2019-03-16

1653 Extinction-resistant attention to long-term conditioned threat is indexed by selective visuocortical alpha suppression in humans

Panitz, C.; Keil, A.; Mueller, E. M.

10.1101/533141 — neuroscience — Posted on 2019-03-16

1654 Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community

Hart, S. F.; Pineda, J. M. B.; Chen, C.-C.; Green, R.; Shou, W.

10.1101/530287 — microbiology — Posted on 2019-03-16

1655 Revealing multi-scale population structure in large cohorts

Diaz-Papkovich, A.; Anderson-Trocme, L.; Gravel, S.

10.1101/423632 — genomics — Posted on 2019-03-16

1656 Evolutionary significance of structural segments trailing beta strand 5 and alpha helix 10 in the design of catalytically active NAL superfamily

Prem Kumar, M. K.; Manoharan, P.

10.1101/505230 — evolutionary biology — Posted on 2019-03-16

1657 Disorder Atlas: web-based software for the proteome-based interpretation of intrinsic disorder predictions

Vincent, M.; Schnell, S.

10.1101/060699 — bioinformatics — Posted on 2019-03-16

1658 Practice of Cardiac Auscultation: Clinical perspectives and its implications on computer aided diagnosis

Mandal, S.; Martis, R. J.; Mandana, K.; Acharya, R. U.; Chatterjee, J.; Ray, A. K.

10.1101/013334 — bioengineering — Posted on 2019-03-16

1659 Genome-wide ancestry and introgression in a Zambian baboon hybrid zone

Chiou, K. L.; Bergey, C. M.; Burrell, A. S.; Disotell, T. R.; Rogers, J.; Jolly, C. J.; Phillips-Conroy, J. E.

10.1101/578781 — evolutionary biology — Posted on 2019-03-16

1660 High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations

Jung, J.; Grant, T.; Thomas, D. R.; Diehnelt, C. W.; Grigorieff, N.; Joshua-Tor, L.

10.1101/580167 — biophysics — Posted on 2019-03-16

1661 Age Differences in Hemispheric Lateralization in Spatial and Verbal Visual Working Memory

Sander, M. C.; Maier, P. M.; Napiorkowski, N.; Finke, K.; Toellner, T.; Mueller, H. J.; Lindenberger, U.; Werkle-Bergner, M.; Wiegand, I.

10.1101/577858 — neuroscience — Posted on 2019-03-16

1662 EpiSAFARI: Sensitive detection of valleys in epigenetic signals for enhancing annotations of functional elements

Harmanci, A. O.; Serin Harmanci, A.; Swaminathan, J.; Gopalakrishnan, V.

10.1101/579847 — bioinformatics — Posted on 2019-03-16

1663 Prenatal thyroid hormone exposure increases growth but not oxidative stress in a wild passerine species

Sarraude, T.; Hsu, B.-Y.; Groothuis, T. G. G.; Ruuskanen, S.

10.1101/578047 — physiology — Posted on 2019-03-16

1664 Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

Kals, M.; Nikopensius, T.; Läll, K.; Pärn, K.; Sikka, T. T.; Suvisaari, J.; Salomaa, V.; Ripatti, S.; Palotie, A.; Metspalu, A.; Esko, T.; Palta, P.; Mägi, R.

10.1101/579201 — genomics — Posted on 2019-03-16

1665 Deep Learning with Multimodal Representation for Pancancer Prognosis Prediction

Cheerla, A.; Gevaert, O.

10.1101/577197 — bioinformatics — Posted on 2019-03-16

1666 The Beacon Calculus: A formal method for the flexible and concise modelling of biological systems

Boemo, M. A.; Cardelli, L.; Nieduszynski, C. A.

10.1101/579029 — systems biology — Posted on 2019-03-16

1667 Effect of Antimicrobial Peptides HNP-1 and hBD-1 on Staphylococcus aureus Clinical Strains in vitro and in vivo.

Bolatchiev, A.; Baturin, V.; Bazikov, I.; Maltsev, A.; Kunitsina, E.

10.1101/578278 — pharmacology and toxicology — Posted on 2019-03-16

1668 Short-Term Synaptic Dynamics Control the Activity Phase of Neurons in an Oscillatory Network

Martinez, D.; Anwar, H.; Bose, A.; Bucher, D.; Nadim, F.

10.1101/578617 — neuroscience — Posted on 2019-03-16

1669 Reward boosts neural coding of task rules to optimise cognitive flexibility

Hall-McMaster, S.; Muhle-Karbe, P.; Myers, N.; Stokes, M.

10.1101/578468 — neuroscience — Posted on 2019-03-16

1670 THE HIDDEN REPERTOIRE OF BRAIN DYNAMICS AND DYSFUNCTION

McIntosh, R.; Jirsa, V.

10.1101/578443 — neuroscience — Posted on 2019-03-16

1671 Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides

Tanti, A.; Lutz, P.-E.; Kim, J. J.; O'Leary, L.; Turecki, G.; Mechawar, N.

10.1101/578807 — neuroscience — Posted on 2019-03-16

1672 Pan-filovirus one-step reverse transcription-polymerase chain reaction screening assay

Kopp, K.; Smith, I.; Klein, R.; Todd, S.; Marsh, G. A.; Ward, A.

10.1101/579458 — molecular biology — Posted on 2019-03-16

1673 Interplay of primary bovine lymphocytes and Mycobacterium avium subsp. paratuberculosis shows distinctly different proteome changes and immune pathways in host-pathogen interaction

Kleinwort, K. J. H.; Hauck, S. M.; Degroote, R. L.; Lutterberg, K.; Scholz, A. M.; Hoelzel, C.; Maertlbauer, E. P.; Deeg, C. A.

10.1101/578187 — immunology — Posted on 2019-03-16

1674 A draft genome sequence of the miniature parasitoid wasp, Megaphragma amalphitanum

Nedoluzhko, A.; Sharko, F.; Le, B.; Tsygankova, S.; Boulygina, E.; Rastorguev, S.; Sokolov, A.; Rodriguez, F.; Mazur, A.; Polilov, A.; Benton, R.; Evgen'ev, M.; Arkhipova, I.; Prokhortchouk, E.; Skryabin, K.

10.1101/579052 — genomics — Posted on 2019-03-16

1675 High-Affinity Binding of Chemokine Analogs that Display Ligand Bias at the HIV-1 Co-receptor CCR5

Rico, C. A.; Berchiche, Y. A.; Horioka, M.; Peeler, J. C.; Lorenzen, E.; Tian, H.; Kazmi, M. A.; Furstenberg, A.; Gaertner, H.; Hartley, O.; Sakmar, T. P.; Huber, T.

10.1101/575795 — biophysics — Posted on 2019-03-16

1676 Systematic and comprehensive benchmarking of an exome sequencing based germline copy-number variant detection pipeline in a clinical setting

Rajagoapalan, R.; Murrell, J.; Jayaraman, P.; Wu, C.; Luo, M.; Conlin, L. K.

10.1101/579755 — bioinformatics — Posted on 2019-03-16

1677 Evolutionary dynamics in structured populations under strong population genetic forces

Feder, A. F.; Pennings, P. S.; Hermisson, J.; Petrov, D. A.

10.1101/579854 — evolutionary biology — Posted on 2019-03-16

1678 Applying continuous functional traits to large brown macroalgae: variation across tidal emersion and wave exposure gradients

Cappelatti, L.; Mauffrey, A.; Griffin, J. N.

10.1101/577825 — ecology — Posted on 2019-03-16

1679 Metabolic reprogramming from glycolysis to amino acid utilization in cardiac HIF1α deficient mice.

Menendez-Montes, I.; Escobar, B.; Palacios, B.; Gomez, M. J.; Bonzon, E.; Ferrarini, A.; Alonso, A. V.; Jimenez-Borreguero, L. J.; Vazquez, J.; Martin-Puig, S.

10.1101/579433 — developmental biology — Posted on 2019-03-16

1680 Human intestinal enteroids with inducible neurogenin-3 expression as a novel model of gut hormone secretion

Chang-Graham, A. L.; Danhof, H. A.; Engevik, M. A.; Tomaro-Duchesneau, C.; Karandikar, U. C.; Estes, M. K.; Versalovic, J.; Britton, R. A.; Hyser, J. M.

10.1101/579698 — microbiology — Posted on 2019-03-16

1681 Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits

Gleason, K. J.; Yang, F.; Pierce, B.; He, X.; Chen, L. S.

10.1101/579581 — genomics — Posted on 2019-03-16

1682 Pervasive convergent evolution and extreme phenotypes define chaperone requirements of protein homeostasis

Draceni, Y.; Pechmann, S.

10.1101/578724 — evolutionary biology — Posted on 2019-03-16

1683 Recent global changes have decoupled species richness from specialization patterns in North American birds

Mimet, A.; Buitenwerf, R.; Sandel, B.; Svenning, J.-C.; Normand, S.

10.1101/577841 — ecology — Posted on 2019-03-16

1684 Estimation of Membrane Curvature for Cryo-Electron Tomography

Kalemanov, M.; Collado, J. F.; Baumeister, W.; Fernandez-Busnadiego, R.; Martinez-Sanchez, A.

10.1101/579060 — bioinformatics — Posted on 2019-03-16

1685 Scalable image processing techniques for quantitative analysis of volumetric biological images from light-sheet microscopy

Swaney, J.; Kamentsky, L.; Evans, N. B.; Xie, K.; Park, Y.-G.; Drummond, G.; Yun, D. H.; Chung, K.

10.1101/576595 — bioengineering — Posted on 2019-03-16

1686 Robustness and timing of cellular differentiation through population-based symmetry breaking

Stanoev, A.; Schroeter, C.; Koseska, A.

10.1101/578898 — systems biology — Posted on 2019-03-16

1687 Pax6 and KDM5C co-occupy a subset of developmentally critical genes including Notch signaling regulators in neural progenitors

Gaudenzi, G.; Dethlefsen, O.; Walfridsson, J.; Hermanson, O.

10.1101/579219 — molecular biology — Posted on 2019-03-16

1688 Microbiological, biochemical, physicochemical surface properties and biofilm forming ability of Brettanomyces bruxellensis

Dimopoulou, M.; Renault, M.; Dols-Lafargue, M.; Albertin, W.; Herry, J.-M.; Bellon-Fontaine, M.-N.; Masneuf-Pomarede, I.

10.1101/579144 — microbiology — Posted on 2019-03-16

1689 Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001

Devi, S.; Kiesewalter, H. T.; Kovacs, R.; Frisvad, J.; Weber, T.; Larsen, T. O.; Kovacs, A. T.; Ding, L.

10.1101/577817 — microbiology — Posted on 2019-03-16

1690 Blood cells of adult Drosophila do not expand, but control survival after bacterial infection by induction of Drosocin around their reservoir at the respiratory epithelia

Sanchez Bosch, P.; Makhijani, K.; Herboso, L.; Gold, K. S.; Baginsky, R.; Woodcock, K. J.; Alexander, B.; Kukar, K.; Corcoran, S.; Ouyang, D.; Wong, C.; Ramond, E. J.; Rhiner, C.; Moreno, E.; Lemaitre, B.; Geissmann, F.; Brueckner, K.

10.1101/578864 — immunology — Posted on 2019-03-16

1691 Proteome-wide signatures of function in highly diverged intrinsically disordered regions

Zarin, T.; Strome, B.; Nguyen Ba, A. N.; Alberti, S.; Forman-Kay, J.; Moses, A. M.

10.1101/578716 — genomics — Posted on 2019-03-16

1692 Balancing selection shapes the Intracellular Pathogen Response in natural Caenorhabditis elegans populations

van Sluijs, L.; Bosman, K. J.; Pankok, F.; Blokhina, T.; Riksen, J. A. G.; Snoek, B.; Pijlman, G. P.; Kammenga, J. E.; Sterken, M. G.

10.1101/579151 — genetics — Posted on 2019-03-16

1693 The Origin and Early Evolution of the Legumes are a Complex Paleopolyploid Phylogenomic Tangle closely associated with the Cretaceous-Paleogene (K-Pg) Boundary

Koenen, E.; Ojeda, D.; Steeves, R.; Migliore, J.; Bakker, F.; Wieringa, J.; Kidner, C.; Hardy, O.; Pennington, T.; Herendeen, P.; Bruneau, A.; Hughes, C.

10.1101/577957 — evolutionary biology — Posted on 2019-03-16

1694 ProtCID: A tool for hypothesis generation of the structures of protein interactions

Xu, Q.; Dunbrack, R. L.

10.1101/579862 — bioinformatics — Posted on 2019-03-16

1695 Higher order analysis of gene correlations by tensor decomposition

Yahyanejad, F.

10.1101/579276 — bioinformatics — Posted on 2019-03-16

1696 treeClust improves protein co-regulation analysis due to robust selectivity for close linear relationships

Kustatscher, G.; Grabowski, P.; Rappsilber, J.

10.1101/578971 — systems biology — Posted on 2019-03-16

1697 An approximate derivate-based controller for regulating gene expression

Modi, S.; Dey, S.; Singh, A.

10.1101/579615 — synthetic biology — Posted on 2019-03-16

1698 High angular resolution diffusion MRI reveals conserved and deviant programs in the paths that guide human cortical circuitry

Charvet, C. J.; Das, A.; Song, J. W.; Tindall-Burgess, D. J.; Kabaria, P.; Dai, G.; Kane, T.; Takahashi, E.

10.1101/576967 — neuroscience — Posted on 2019-03-16

1699 Cannabis-associated symptom profiles in patients with first episode psychosis and population controls

Quattrone, D.; Ferraro, L.; Tripoli, G.; La Cascia, E.; Quigley, H.; EU-GEI WP2 group, ; Gayer-Anderson, C.; Jones, P. B.; Kirkbride, J. B.; La Barbera, D.; Tarricone, I.; Lynskey, M. T.; Freeman, T. P.; Sham, P. C.; Cardno, A.; Vassos, E.; van Os, J.; Morgan, C.; Reininghaus, U.; Lewis, C. M.; Murray, R. M.; Di Forti, M.

10.1101/577932 — neuroscience — Posted on 2019-03-16

1700 Host metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation

Hendrix, H.; Kogadeeva, M.; Zimmermann, M.; Sauer, U.; De Smet, J.; Muchez, L.; Lissens, M.; Staes, I.; Voet, M.; Wagemans, J.; Ceyssens, P.-J.; Noben, J.-P.; Aertsen, A.; Lavigne, R.

10.1101/577908 — microbiology — Posted on 2019-03-16

1701 Eye in a Disk: eyeIntegration human pan-eye and body transcriptome database version 1.0

Swamy, V.; McGaughey, D.

10.1101/579482 — genomics — Posted on 2019-03-16

1702 Is evolution predictable? Quantitative genetics under complex genotype-phenotype maps

Milocco, L.; Salazar-Ciudad, I.

10.1101/578021 — evolutionary biology — Posted on 2019-03-16

1703 Resilience Analysis for Competing Populations

Cesar Fassoni, A.; de Carvalho Braga, D.

10.1101/578609 — ecology — Posted on 2019-03-16

1704 Embryonic geometry underlies phenotypic variation in decanalized conditions

Huang, A.; Saunders, T. E.

10.1101/579623 — developmental biology — Posted on 2019-03-16

1705 Inferring biophysical models of evolution from genome-wide patterns of codon usage

Kion-Crosby, W. B.; Manhart, M.; Morozov, A. V.

10.1101/578815 — biophysics — Posted on 2019-03-16

1706 Molecular Predicting Drought Tolerance in Maize Inbred Lines by Machine Learning Approaches

Beiki, A. H.

10.1101/578880 — bioinformatics — Posted on 2019-03-16

1707 Hearing impairment due to Mir183/96/182 mutations suggests both loss and gain of function effects

Lewis, M. A.; Di Domenico, F.; Ingham, N. J.; Prosser, H. M.; Steel, K. P.

10.1101/579003 — systems biology — Posted on 2019-03-16

1708 Efficient parameterization of large-scale dynamic models based on relative measurements

Schmiester, L.; Schaelte, Y.; Froehlich, F.; Hasenauer, J.; Weindl, D.

10.1101/579045 — systems biology — Posted on 2019-03-16

1709 Epistatic Networks Associated with Parent-of-Origin Effects on Metabolic Traits

Macias-Velasco, J. F.; St. Pierre, C. L.; Wayhart, J. P.; Yin, L.; Spears, L.; Funai, K.; Cheverud, J. M.; Semenkovich, C. F.; Lawson, H. A.

10.1101/579748 — systems biology — Posted on 2019-03-16

1710 Marine sediments illuminate Chlamydiae diversity and evolution

Dharamshi, J.; Tamarit, D.; Eme, L.; Stairs, C.; Martijn, J.; Homa, F.; Jorgensen, S.; Spang, A.; Ettema, T. J. G.

10.1101/577767 — microbiology — Posted on 2019-03-16

1711 Myosin II isoforms play distinct roles in adherens junction biogenesis

Ladoux, B.; Mege, R.-M.; Dang, T.; Heuze, M.; Van Hest, J.; Sankara, G.; Marcq, P.; D'Alessandro, J.; Cellerin, V.; Williams, D. S.

10.1101/578997 — cell biology — Posted on 2019-03-16

1712 Gene Expression Mediated Antiproliferative Potential and Safety of Selected Medicinal Plants Against Cancerous and Normal Cells

MBUGUA, R. W.; Mwitari, P. G.; Njagi, E. M.; Ngule, C. M.

10.1101/578948 — cancer biology — Posted on 2019-03-16

1713 Gender differences in attitudes toward death among Chinese university students: A survey in hunan and Heilongjiang province

Wang, Y.; Tang, S.; Hu, X.; Qin, C.; Ma, L.; Li, Y.; Khoshnood, K.; Sun, M.

10.1101/578955 — scientific communication and education — Posted on 2019-03-16

1714 Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma

Megquier, K.; Turner-Maier, J.; Swofford, R.; Kim, J.-H.; Sarver, A. L.; Wang, C.; Sakthikumar, S.; Johnson, J.; Koltookian, M.; Lewellen, M.; Scott, M. C.; Graef, A. J.; Borst, L.; Tonomura, N.; Alfoldi, J.; Painter, C.; Thomas, R.; Karlsson, E. K.; Breen, M.; Modiano, J. F.; Elvers, I.; Lindblad-Toh, K.

10.1101/570879 — genomics — Posted on 2019-03-15

1715 Changes in gene expression shift and switch genetic interactions

Li, X.; Lalic, J.; Baeza-Centurion, P.; Dhar, R.; Lehner, B.

10.1101/578419 — genetics — Posted on 2019-03-15

1716 Cingulate Cortex Atrophy is Associated with Hearing Loss in Presbycusis with Cochlear Amplifier Dysfunction

Belkhiria, C.; Vergara, R. C.; San Martin, S.; Leiva, A.; Marcenaro, B.; Martinez, M.; Delgado, C.; Delano, P. H.

10.1101/574228 — neuroscience — Posted on 2019-03-15

1717 Timing and Duration of Gbx2 Expression Delineates Thalamocortical and Dopaminergic Medial Forebrain Bundle Circuitry

Normand, E. A.; Browning, C.; Zervas, M.

10.1101/579664 — neuroscience — Posted on 2019-03-15

1718 Comprehensive mutation profiling of both cfDNA and CTCs in gynecological cancer patients

Lee, S.-Y.; Chae, D.-k.; An, J.; Jung, S.; Chae, C. H.; Bhak, J.; Kim, B. C.; Cho, D.-H.

10.1101/566786 — genetics — Posted on 2019-03-15

1719 The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology

Hahn, I.; Voelzmann, A.; Liew, Y.-T.; Costa-Gomes, B.; Prokop, A.

10.1101/577320 — cell biology — Posted on 2019-03-15

1720 Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblasts

Lerche, M.; Elosegui-Artola, A.; Guzman, C.; Georgiadou, M.; Kechagia, J. Z.; Gulberg, D.; Roca-Cusachs, P.; Peuhu, E.; Ivaska, J.

10.1101/570721 — cell biology — Posted on 2019-03-15

1721 Branching developmental pathways through high dimensional single cell analysis in trajectory space

Dermadi, D.; Bscheider, M.; Bjegovic, K.; Lazarus, N. H.; Szade, A.; Hadeiba, H.; Butcher, E. C.

10.1101/336313 — bioinformatics — Posted on 2019-03-15

1722 Unsupervised Toxoplasma gondii Recognition by Fuzzy Cycle Generative Adversarial Network

Li, S.; Li, A.; Lara, D. A. M.; Gomez Marin, J. E.; Zhang, Y.

10.1101/567891 — bioinformatics — Posted on 2019-03-15

1723 Effects of dietary taurine level on visual function in European sea bass (Dicentrarchus labrax)

Brill, R.; Horodysky, A.; Place, A.; Larkin, M.; Reimschuessel, R.

10.1101/577023 — physiology — Posted on 2019-03-15

1724 Studies of allosteric coupling in KcsA using a constitutively open mutant

Sun, Z.; Xu, Y.; Zhang, D.; McDermott, A. E.

10.1101/567024 — biophysics — Posted on 2019-03-15

1725 Object Detection Networks and Augmented Reality for Cellular Detection in Fluorescence Microscopy Acquisition and Analysis.

Waithe, D.; Brown, J. M.; Reglinski, K.; Diez-Sevilla, I.; Roberts, D.; Eggeling, C.

10.1101/544833 — bioinformatics — Posted on 2019-03-15

1726 The sequence of the extruded non-template strand determines the architecture of R-loops.

Carrasco-Salas, Y.; Malapert, A.; Sulthana, S.; Molcrette, B.; Chazot-Franguiadakis, L.; Bernard, P.; Chedin, F.; Faivre-Moskalenko, C.; Vanoosthuyse, V.

10.1101/576561 — molecular biology — Posted on 2019-03-15

1727 Evaluating potential drug targets through human loss-of-function genetic variation

Minikel, E. V.; Karczewski, K. J.; Martin, H. C.; Cummings, B. B.; Whiffin, N.; Alfoldi, J.; Trembath, R. C.; van Heel, D. A.; Daly, M. J.; Genome Aggregation Database Production Team, ; Genome Aggregation Database Consortium, ; Schreiber, S. L.; MacArthur, D. G.

10.1101/530881 — genomics — Posted on 2019-03-15

1728 The Patchy Distribution of Restriction-Modification System Genes and the Conservation of Orphan Methyltransferases in Halobacteria.

Fullmer, M. S.; Ouellette, M.; Louyakis, A.; Papke, R. T.; Gogarten, J. P.

10.1101/551721 — genomics — Posted on 2019-03-15

1729 Chromatin arranges in filaments of blobs with nanoscale functional zonation

Miron, E.; Oldenkamp, R.; Pinto, D. M.; Brown, J. M.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Buckle, V.; Schermelleh, L.

10.1101/566638 — genomics — Posted on 2019-03-15

1730 Pattern separation is the key driver of expectation-modulated memory

Frank, D.; Montaldi, D.

10.1101/577791 — neuroscience — Posted on 2019-03-15

1731 SpectralTAD: an R package for defining a hierarchy of Topologically Associated Domains using spectral clustering

Cresswell, K. G.; Stansfield, J. C.; Dozmorov, M. G.

10.1101/549170 — bioinformatics — Posted on 2019-03-15

1732 Constructing a Draft Map of the Cannabis Proteome

Jenkins, C.; Orsburn, B.

10.1101/577635 — plant biology — Posted on 2019-03-15

1733 Effectiveness and selectivity of a heroin conjugate vaccine to attenuate heroin, 6-acetylmorphine, and morphine antinociception in rats: Comparison with naltrexone

Schwienteck, K. L.; Blake, S.; Bremer, P. T.; Poklis, J. L.; Townsend, E. A.; Negus, S. S.; Banks, M. L.

10.1101/577494 — pharmacology and toxicology — Posted on 2019-03-15

1734 Resolving multisensory and attentional influences across cortical depth in sensory cortices

Gau, R.; Bazin, P.-L.; Trampel, R.; Turner, R.; Noppeney, U.

10.1101/548933 — neuroscience — Posted on 2019-03-15

1735 HiLDA: a statistical approach to investigate differences in mutational signatures

Yang, Z.; Pandey, P.; Shibata, D.; Conti, D. V.; Marjoram, P.; Siegmund, K.

10.1101/577452 — genomics — Posted on 2019-03-15

1736 Neural population dynamics in prefrontal cortex and hippocampus during paired-associate learning

Liu, Y.; Brincat, S. L.; Miller, E. K.; Hasselmo, M. E.

10.1101/578849 — neuroscience — Posted on 2019-03-15

1737 Social hierarchy regulates ocular dominance plasticity in adult male mice.

Balog, J.; Hintz, F.; Isstas, M.; Teichert, M.; Winter, C.; Lehmann, K.

10.1101/579169 — neuroscience — Posted on 2019-03-15

1738 A Drosophila model of neuronal ceroid lipofuscinosis CLN4 reveals a hypermorphic gain of function mechanism

Imler, E.; Pyon, J. S.; Kindelay, S.; Zhang, Y.-q.; Chandra, S. S.; Zinsmaier, K. E.

10.1101/579771 — neuroscience — Posted on 2019-03-15

1739 Timing and Duration of Gbx2 Expression Delineates Thalamocortical and Dopaminergic Medial Forebrain Bundle Circuitry

Normand, E. A.; Browning, C.; Zervas, M.

10.1101/579664 — neuroscience — Posted on 2019-03-15

1740 ESCRT-III/Vps4 controls heterochromatin-nuclear envelope attachments

Pieper, G. H.; Sprenger, S.; Teis, D.; Oliferenko, S.

10.1101/579805 — cell biology — Posted on 2019-03-15

1741 Hypothalamic-extended amygdala circuit regulates temporal discounting

Rossi, M.; Li, H.; Watson, G.; Moore, H. G.; Cai, M. T. T.; Kim, N.; Vokt, K.; Lu, D.; Bartholomew, R.; Yin, H.

10.1101/577973 — neuroscience — Posted on 2019-03-15

1742 Simple Framework for Constructing Functional Spiking Recurrent Neural Networks

Kim, R.; Li, Y.; Sejnowski, T. J.

10.1101/579706 — neuroscience — Posted on 2019-03-15

1743 Effects of transcranial alternating-current stimulation to secondary motor areas on cortical oscillations in stroke patients

Krawinkel, L. A.; Boenstrup, M.; Feldheim, J. F.; Schulz, R.; Backhaus, W.; Schneider, T. R.; Misselhorn, J.; Cheng, B.; Gerloff, C.

10.1101/529818 — neuroscience — Posted on 2019-03-15

1744 An EDS1-SAG101 complex functions in TNL-mediated immunity in Solanaceae

Gantner, J.; Ordon, J.; Kretschmer, C.; Guerois, R.; Stuttmann, J.

10.1101/511956 — plant biology — Posted on 2019-03-15

1745 A dynamic neural network model for predicting risk of Zika in real-time

Akhtar, M.; Kraemer, M. U.; Gardner, L.

10.1101/466581 — epidemiology — Posted on 2019-03-15

1746 Hundreds of yeast mRNAs form a separately addressable, translation elongation-controlled regulon

Kazana, E.; von der Haar, T.

10.1101/513705 — molecular biology — Posted on 2019-03-15

1747 Cyto-architecture constrains a photoactivation induced tubulin gradient in the syncytial Drosophila embryo

Thukral, S.; Kaity, B.; Dey, B.; Sharma, S.; Nandi, A.; Mitra, M.; Rikhy, R.

10.1101/520031 — developmental biology — Posted on 2019-03-15

1748 Follicle-stimulating hormone and luteinizing hormone increase Ca2+ in the granulosa cells of mouse ovarian follicles

Egbert, J. R.; Fahey, P. G.; Reimer, J.; Owen, C. M.; Evsikov, A. V.; Nikolaev, V. O.; Griesbeck, O.; Ray, R. S.; Tolias, A. S.; Jaffe, L. A.

10.1101/520122 — cell biology — Posted on 2019-03-15

1749 Comparative assessment of long-read error-correction software applied to RNA-sequencing data

Ishi Soares de Lima, L.; Marchet, C.; Caboche, S.; Da Silva, C.; Istace, B.; Aury, J.-M.; Touzet, H.; Chikhi, R.

10.1101/476622 — bioinformatics — Posted on 2019-03-15

1750 Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase

Kung, W.-W.; Ramachandran, S.; Makukhin, N.; Bruno, E.; Ciulli, A.

10.1101/470187 — biochemistry — Posted on 2019-03-15

1751 Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Szewczyk, M. M.; Ishikawa, Y.; Organ, S.; Sakai, N.; Li, F.; Ackloo, S.; Eram, M. S.; Dilworth, D.; Fukushi, H.; Harding, R.; dela Sena, C. C.; Sugo, T.; Hayashi, K.; Macleod, D.; Zepeda, C.; Takagi, S.; Al-Awar, R.; Richard, S.; Takizawa, M.; Arrowsmith, C. H.; Vedadi, M.; Brown, P. J.; Nara, H.; Barsyte-Lovejoy, D.

10.1101/503136 — biochemistry — Posted on 2019-03-15

1752 The conflict between adaptation and dispersal for maintaining biodiversity in changing environments

Thompson, P. L.; Fronhofer, E. A.

10.1101/490722 — ecology — Posted on 2019-03-15

1753 TFIIIC binding to Alu elements controls gene expression via chromatin looping and histone acetylation

Ferrari, R.; Llobet Cucalon, L. I.; Di Vona, C.; Le Dilly, F.; Vidal, E.; Lioutas, A.; Oliete, J. Q.; Jochem, L.; Cutts, E.; Dieci, G.; Alessandro, V.; Teichmann, M.; de la Luna, S.; Beato, M.

10.1101/455733 — genomics — Posted on 2019-03-15

1754 Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

Booth, A. J.; Yue, Z.; Eykelenboom, J. K.; Stiff, T.; Luxton, G. G.; Hochegger, H.; Tanaka, T. U.

10.1101/459750 — cell biology — Posted on 2019-03-15

1755 pyMeSHSim: an integrative python package to realize biomedical named entity recognition, normalization and comparison

Luo, Z.-H.; Shi, M.-W.; Yang, Z.; Zhang, H.-Y.; Chen, Z.-X.

10.1101/459172 — bioinformatics — Posted on 2019-03-15

1756 Functionally Coherent Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling

Overton, I. M.; Sims, A. H.; Owen, J. A.; Heale, B.; Ford, M. J.; Lubbock, A. L. R.; Pairo-Castineira, E.; Essafi, A.

10.1101/455709 — systems biology — Posted on 2019-03-15

1757 A comprehensive framework to capture the arcana of neuroimaging analysis

Close, T. G.; Ward, P. G. D.; Sforazzini, F.; Goscinski, W.; Chen, Z.; Egan, G.

10.1101/447649 — bioinformatics — Posted on 2019-03-15

1758 PathMe: Merging and exploring mechanistic pathway knowledge

Domingo-Fernandez, D.; Mubeen, S.; Marin-Llao, J.; Hoyt, C.; Hofmann-Apitius, M.

10.1101/451625 — bioinformatics — Posted on 2019-03-15

1759 The influence of fluctuating population densities on evolutionary dynamics

Pisa, H.; Hermisson, J.; Polechova, J.

10.1101/444273 — evolutionary biology — Posted on 2019-03-15

1760 Adjustment for index event bias in genome-wide association studies of subsequent events

Dudbridge, F.; Allen, R. J.; Sheehan, N. A.; Schmidt, A. F.; Lee, J. C.; Jenkins, R. G.; Wain, L. V.; Hingorani, A. D.; Patel, R. S.

10.1101/436063 — epidemiology — Posted on 2019-03-15

1761 Assessment of risk to hoary squash bees (Peponapis pruinosa) and other ground-nesting bees from systemic insecticides in agricultural soil

Willis Chan, D. S.; Prosser, R. S.; Rodriguez Gil, J. L.; Raine, N. E.

10.1101/434498 — ecology — Posted on 2019-03-15

1762 scRNA-seq mixology: towards better benchmarking of single cell RNA-seq analysis methods

Tian, L.; Dong, X.; Freytag, S.; Le Cao, K.-A.; Su, S.; JalalAbadi, A.; Amann-Zalcenstein, D.; Weber, T. S.; Seidi, A.; Jabbari, J. S.; Naik, S.; Ritchie, M. E.

10.1101/433102 — bioinformatics — Posted on 2019-03-15

1763 Using optically-pumped magnetometers to measure magnetoencephalographic signals in the human cerebellum

Lin, C.-H.; Tierney, T. M.; Holmes, N.; Boto, E.; Leggett, J.; Bestmann, S.; Bowtell, R.; Brookes, M. J.; Miall, R. C.; Barnes, G. R.

10.1101/425447 — neuroscience — Posted on 2019-03-15

1764 Human cortical neural stem cells generate regional organizer states in vitro before committing to excitatory neuronal fates

Micali, N.; Kim, S.-K.; Diaz-Bustamante, M.; Stein-O'Brien, G.; Seo, S.; Shin, J.-H.; Rash, B. G.; Ma, S.; Olivares, N. A.; Arellano, J.; Maynard, K. R.; Fertig, E. J.; Cross, A. J.; Burli, R.; Brandon, N. J.; Weinberger, D. R.; Chenoweth, J. G.; Hoeppner, D. J.; Sestan, N.; Rakic, P.; Colantuoni, C.; McKay, R. D.

10.1101/577544 — neuroscience — Posted on 2019-03-15

1765 Computational estimation of ms-sec atomistic folding times

Adhikari, U.; Mostofian, B.; Copperman, J.; Petersen, A.; Zuckerman, D. M.

10.1101/427393 — biophysics — Posted on 2019-03-15

1766 Dissociating refreshing and elaboration and their impacts on memory

Bartsch, L. M.; Loaiza, V. M.; Jäncke, L.; Oberauer, K.; Lewis-Peacock, J.

10.1101/423277 — neuroscience — Posted on 2019-03-15

1767 Neuronal programming by microbiota enables environmental regulation of intestinal motility

Obata, Y.; Boeing, S.; Castano, A.; Carina Bon-Frauches, A.; Gomez de Aguero, M.; Boesmans, W.; Yilmaz, B.; Lopes, R.; Huseynova, A.; Maradana, M. R.; Vanden Berghe, P.; Murray, A. J.; Stockinger, B.; Macpherson, A. J.; Pachnis, V.

10.1101/579250 — neuroscience — Posted on 2019-03-15

1768 Single cell expression variability in highly homogeneous populations of human cells is widespread, is heritable, and implies cell function

Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J.

10.1101/574426 — genomics — Posted on 2019-03-15

1769 Network analysis of whole-brain fMRI dynamics: A new framework based on dynamic communicability

Gilson, M.; Kouvaris, N. E.; Deco, G.; Mangin, J.-F.; Poupon, C.; Lefranc, S.; Riviere, D.; Zamora-Lopez, G.

10.1101/421883 — neuroscience — Posted on 2019-03-15

1770 The joint evolution of lifespan and self-fertilisation

Lesaffre, T.; Billiard, S.

10.1101/420877 — evolutionary biology — Posted on 2019-03-15

1771 Theory on the looping mediated stochastic propulsion of transcription factors along DNA

Murugan, R.

10.1101/418947 — biophysics — Posted on 2019-03-15

1772 Systematic analysis of the Myxococcus xanthus developmental gene regulatory network supports posttranslational regulation of FruA by C-signaling

Saha, S.; Patra, P.; Igoshin, O.; Kroos, L.

10.1101/415331 — molecular biology — Posted on 2019-03-15

1773 Synergy of Topoisomerase and Structural-Maintenance-of Chromosomes Proteins Creates a Universal Pathway to Simplify Genome Topology

Orlandini, E.; Marenduzzo, D.; Michieletto, D.

10.1101/410019 — biophysics — Posted on 2019-03-15

1774 Deep Learning of Representations for Transcriptomics-based Phenotype Prediction

Smith, A. M.; Walsh, J. R.; Long, J.; Davis, C. B.; Henstock, P.; Hodge, M. R.; Maciejewski, M.; Mu, X. J.; Ra, S.; Zhao, S.; Ziemek, D.; Fisher, C. K.

10.1101/574723 — bioinformatics — Posted on 2019-03-15

1775 Fine-grained mapping of cortical somatotopies in chronic Complex Regional Pain Syndrome

Mancini, F.; Wang, A. P.; Shira, M. M.; Isherwood, Z. J.; McAuley, J. H.; Iannetti, G.; Sereno, M. I.; Moseley, L.; Rae, C. D.

10.1101/409094 — neuroscience — Posted on 2019-03-15

1776 Sensitivity of Olfactory Sensory Neurons to food cues is tuned to nutritional states by Neuropeptide Y signalling

Kaniganti, T.; Deogade, A.; Maduskar, A.; Mukherjee, A.; Guru, A.; Subhedar, N.; Ghose, A.

10.1101/573170 — neuroscience — Posted on 2019-03-15

1777 A Chromosome-level Sequence Assembly Reveals the Structure of the Arabidopsis thaliana Nd-1 Genome and its Gene Set

Pucker, B.; Holtgraewe, D.; Stadermann, K. B.; Frey, K.; Huettel, B.; Reinhardt, R.; Weisshaar, B.

10.1101/407627 — genomics — Posted on 2019-03-15

1778 Somatic mutations in miRNA genes in lung cancer - potential functional consequences of non-coding sequence variants

Galka-Marciniak, P.; Urbanek-Trzeciak, M. O.; Nawrocka, P. M.; Dutkiewicz, A.; Giefing, M.; Lewandowska, M. A.; Kozlowski, P.

10.1101/579011 — genomics — Posted on 2019-03-15

1779 Single-nucleus RNA sequencing shows convergent evidence from different cell types for altered synaptic plasticity in major depressive disorder.

Nagy, C.; Maitra, M.; Tanti, A.; Suderman, M.; Theroux, J.-F.; Mechawar, N.; Ragoussis, J.; Turecki, G.

10.1101/384479 — neuroscience — Posted on 2019-03-15

1780 Jomon genome sheds light on East Asian population history

Gakuhari, T.; Nakagome, S.; Rasumussen, S.; Allentoft, M.; Sato, T.; Korneliussen, T.; Chuinneagain, B. N.; Matsumae, H.; Koganebuchi, K.; Schmidt, R.; Mizushima, S.; Kondo, O.; Shigehara, N.; Yoneda, M.; Kimura, R.; Ishida, H.; Masuyama, Y.; Yamada, Y.; Tajima, A.; Shibata, H.; Toyoda, A.; Tsurumoto, T.; Wakebe, T.; Shitara, H.; Hanihara, T.; Willerslev, E.; Sikora, M.; Oota, H.

10.1101/579177 — genomics — Posted on 2019-03-15

1781 Sympatric versus allopatric evolutionary contexts shape differential immune response in Biomphalaria / Schistosoma interaction.

Portet, A.; Pinaud, S.; Chaparro, C.; Galinier, R.; Dheilly, N. M.; Charriere, G.; Allienne, J.-F.; Duval, D.; Gourbal, B.

10.1101/378034 — immunology — Posted on 2019-03-15

1782 Supra-threshold perception and neural representation of tones presented in noise in conditions of masking release

Egger, K.; Dau, T.; Epp, B.

10.1101/575720 — neuroscience — Posted on 2019-03-15

1783 Locus coeruleus integrity preserves memory performance across the adult life span

Dahl, M. J.; Mather, M.; Duezel, S.; Bodammer, N. C.; Lindenberger, U.; Kuehn, S.; Werkle-Bergner, M.

10.1101/332098 — neuroscience — Posted on 2019-03-15

1784 Zinc intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC

Lefrancois, L. H.; Kalinina, V.; Cardenal-Munoz, E.; Hanna, N.; Koliwer-Brandl, H.; Appiah, J.; Leuba, F.; Hilbi, H.; Soldati, T.; Barisch, C.

10.1101/575217 — cell biology — Posted on 2019-03-15

1785 Impression cytology is a non-invasive and effective method for ocular cell obtention from babies with Congenital Zika Syndrome: perspectives in OMIC studies.

Barbosa, R. H.; dos Santos, M. L. B.; Silva, T. P.; Rosa-Fernandes, L.; Pinto, A.; Spinola, P.; Bonvicino, C.; Valverde, P.; Lucena, E.; Palmisano, G.; Melo, R.; Cardoso, C.; Lemos, B.

10.1101/577668 — molecular biology — Posted on 2019-03-15

1786 Direct proteolytic control of an extracytoplasmic function RNA polymerase sigma factor

Bilyk, B.; Kim, S.; Baker, T. A.; Seipke, R. F.

10.1101/576462 — microbiology — Posted on 2019-03-15

1787 Unbiased metagenomic sequencing for pediatric meningitis in Bangladesh reveals neuroinvasive Chikungunya virus outbreak and other unrealized pathogens

Saha, S.; Ramesh, A.; Kalantar, K. L.; Malaker, R.; Hasanuzzaman, M.; Khan, L. M.; Mayday, M. Y.; Sajib, M. S. I.; Li, L. M.; Langelier, C.; Rahman, H.; Crawford, E. D.; Tato, C. M.; Islam, M.; Juan, Y.-F.; Bourcy, C. d.; Dimitrov, B.; Wang, J.; Tang, J.; Sheu, J.; Egger, R.; Carvalho, T. R. D.; Wilson, M. R.; Saha, S.; DeRisi, J.

10.1101/579532 — genomics — Posted on 2019-03-15

1788 Development of behavioral modernity by hominins around 70,000 years ago was associated with simultaneous acquisition of a novel component of imagination, called prefrontal synthesis, and conversion of a preexisting rich-vocabulary non-recursive communication system to a fully recursive syntactic language

Vyshedskiy, A.

10.1101/166520 — evolutionary biology — Posted on 2019-03-15

1789 Zika virus seroprevalence declines and neutralization antibodies wane in adults following outbreaks in French Polynesia and Fiji

Henderson, A. D.; Aubry, M.; Kama, M.; Vanhomwegen, J.; Teissier, A.; Mariteragi-Helle, T.; Paoaafaite, T.; Manuguerra, J.-C.; Edmunds, J.; Whitworth, J.; Watson, C. H.; Lau, C. L.; Cao-Lormeau, V.-M.; Kucharski, A. J.

10.1101/578211 — epidemiology — Posted on 2019-03-15

1790 Spatial integration of mechanical forces by alpha-actinin establishes actin network symmetry.

Senger, F.; Pitaval, A.; Ennomani, H.; Kurzawa, L.; Blanchoin, L.; Thery, M.

10.1101/578799 — cell biology — Posted on 2019-03-15

1791 Reduced insulin and IGF-1 signalling synergistically extend healthspan in male mice

Walker, A. M. N.; Watt, N. T.; Warmke, N.; Yuldasheva, N. Y.; Drozd, M.; Haywood, N. J.; Skromna, A.; Makava, N.; Wheatcroft, S. B.; Kearney, M. T.; Cubbon, R. M.

10.1101/579110 — cell biology — Posted on 2019-03-15

1792 Rapid light-dependent degradation of fluorescent dyes in chemically-defined media

Morawski, P. A.; Motley, S.; Campbell, D.

10.1101/578856 — cell biology — Posted on 2019-03-15

1793 Tricalbin-mediated contact sites control ER curvature to maintain plasma membrane integrity

Collado, J.; Kalemanov, M.; Martinez-Sanchez, A.; Campelo, F.; Baumeister, W.; Stefan, C.; Fernandez-Busnadiego, R.

10.1101/578427 — cell biology — Posted on 2019-03-15

1794 Rod-shaped tricalbins contribute to PM asymmetry at curved ER-PM contact sites

Hoffmann, P. C.; Bharat, T. A. M.; Wozny, M. R.; Miller, E. A.; Kukulski, W.

10.1101/579128 — cell biology — Posted on 2019-03-15

1795 Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing

Gorbachev, A.; Kulemin, N.; Naumov, V.; Belova, V.; Kwon, D.; Rebrikova, D.; Korostin, D.

10.1101/577080 — genomics — Posted on 2019-03-15

1796 Sci-Hi-C: a single-cell Hi-C method for mapping 3D genome organization in large number of single cells

Ramani, V.; Deng, X.; Qiu, R.; Lee, C.; Disteche, C. M.; Noble, W. S.; Duan, Z.; Shendure, J.

10.1101/579573 — genomics — Posted on 2019-03-15

1797 Kindlin-3 Mutation in Mesenchymal Stem Cells Results in Enhanced Chondrogenesis

Kerr, B.; Shi, L.; Jinnah, A.; Willey, J.; Lennon, D.; Caplan, A.; Byzova, T.

10.1101/578690 — cell biology — Posted on 2019-03-15

1798 Analysis of patient derived xenograft studies in Oncology drug development: impact on design and interpretation of future studies

Dickinson, J.; de Matas, M.; Dickinson, P.; Mistry, H.

10.1101/579136 — cancer biology — Posted on 2019-03-15

1799 Avoiding potential biases in ses.PD estimations with the Picante software package

Molina-Venegas, R.

10.1101/579300 — bioinformatics — Posted on 2019-03-15

1800 Optimization of 3D bioprinting of human neuroblastoma cells using sodium alginate hydrogel

Lewicki, J.; Bergman, J.; Kerins, C.; Hermanson, O.

10.1101/579268 — bioengineering — Posted on 2019-03-15

1801 Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana - Botrytis cinerea pathosystem

Soltis, N. E.; Zhang, W.; Corwin, J. A.; Atwell, S.; Kliebenstein, D. J.

10.1101/577585 — plant biology — Posted on 2019-03-15

1802 Spheroplast-mediated carbapenem tolerance in Gram-negative pathogens

Cross, T.; Ransegnola, B.; Shin, J.-H.; Weaver, A.; Fauntleroy, K.; VanNieuwenhze, M.; Westblade, L.; Dörr, T.

10.1101/578559 — microbiology — Posted on 2019-03-15

1803 Dosing Time Matters

Ruben, M. D.; Smith, D. F.; FitzGerald, G. A.; Hogenesch, J. B.

10.1101/570119 — epidemiology — Posted on 2019-03-15

1804 Live detection of neural stem and glioblastoma cells by an oligothiophene derivative

10.1101/579185 — bioengineering — Posted on 2019-03-15

1805 Multi-grip classification-based prosthesis control with two sensors

Krasoulis, A.; Vijayakumar, S.; Nazarpour, K.

10.1101/579367 — bioengineering — Posted on 2019-03-15

1806 Recombinant spider silk protein matrices facilitate multi-analysis of calcium-signaling in neural stem cell-derived AMPA-responsive neurons

Lewicka, M.; Rebellato, P.; Lewicki, J.; Uhlen, P.; Rising, A.; Hermanson, O.

10.1101/579292 — bioengineering — Posted on 2019-03-15

1807 Puberty timing and adiposity change across childhood and adolescence: disentangling cause and consequence

O'Keeffe, L. M.; Frysz, M.; Bell, J. A.; Howe, L. D.; Fraser, A.

10.1101/578005 — epidemiology — Posted on 2019-03-15

1808 Making Pastoralists Count: Geospatial Methods for the Health Surveillance of Nomadic Populations

Wild, H.; Glowacki, L.; Maples, S.; Mejia-Guevara, I.; Krystosik, A.; Bonds, M. H.; Hiruy, A.; LaBeaud, A. D.; Barry, M.

10.1101/572685 — epidemiology — Posted on 2019-03-15

1809 Selection and co-selection of antibiotic resistances among Escherichia coli by antibiotic use in primary care: an ecological analysis

Pouwels, K.; Muller-Pebody, B.; Smieszek, T.; Hopkins, S.; Robotham, J.

10.1101/573360 — epidemiology — Posted on 2019-03-15

1810 Physical activity interventions for major chronic disease: a matched-pair analysis of Cochrane and non-Cochrane systematic reviews

Hacke, C.; Nunan, D.

10.1101/571901 — epidemiology — Posted on 2019-03-15

1811 A Comparison Of Robust Mendelian Randomization Methods Using Summary Data

Slob, E. A. W.; Burgess, S.

10.1101/577940 — epidemiology — Posted on 2019-03-15

1812 Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

Karjalainen, M. K.; Holmes, M. V.; Wang, Q.; Anufrieva, O.; Kahonen, M.; Lehtimaki, T.; Havulinna, A. S.; Kristiansson, K.; Salomaa, V.; Perola, M.; Viikari, J. S.; Raitakari, O. T.; Jarvelin, M.-R.; Ala-Korpela, M.; Kettunen, J.

10.1101/576504 — epidemiology — Posted on 2019-03-15

1813 SMAUG: Analyzing single-molecule tracks with nonparametric Bayesian statistics

Karslake, J.; Donarski, E. D.; Shelby, S. A.; Demey, L. M.; DiRita, V. J.; Veatch, S. L.; Biteen, J. S.

10.1101/578567 — biophysics — Posted on 2019-03-15

1814 Performance comparison of the Maxim and Sedia Limiting Antigen Avidity assays for incidence surveillance

Sempa, J. B.; Welte, A.; Busch, M. P.; Hall, J.; Hampton, D.; Keating, S. M.; Facente, S. N.; Marson, K.; Parkin, N.; Pilcher, C. D.; Murphy, G.; Grebe, E.; The Consortium for the Evaluation and Performance,

10.1101/572677 — epidemiology — Posted on 2019-03-15

1815 Imaging The Electrical Activity Of Organelles In Living Cells

Matamala, E.; Castillo, C.; Vivar-Casas, J. P.; Brauchi, S. E.

10.1101/578765 — cell biology — Posted on 2019-03-15

1816 Cell-type specific innervation of cortical pyramidal cells at their apical tufts

Karimi, A.; Odenthal, J.; Drawitsch, F.; Boergens, K. M.; Helmstaedter, M.

10.1101/571695 — neuroscience — Posted on 2019-03-15

1817 Circuits that encode and predict alcohol associated preference.

Scaplen, K. M.; Talay, M.; Salamon, S.; Nunez, K. M.; Waterman, A. G.; Gang, S.; Song, S. L.; Barnea, G.; Kaun, K. R.

10.1101/578401 — neuroscience — Posted on 2019-03-15

1818 Rere-dependent Retinoic Acid signaling controls brain asymmetry and handedness

Rebagliati, M.; Vihais-Neto, G.; Petiet, A.; Lange, M.; Michaut, A.; Plassat, J.-L.; Vermot, J.; Riet, F.; Noblet, V.; Brasse, D.; Laquerriere, P.; Cussigh, D.; Dray, N.; Bedu, S.; Gomaa, M. S.; Simons, C.; Meziane, H.; Lehericy, S.; Bally-Cuif, L.; Pourquie, O.

10.1101/578625 — neuroscience — Posted on 2019-03-15

1819 HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4

Raghawan, A. K.; Ramaswami, R.; Radha, V.; Swarup, G.

10.1101/578138 — cell biology — Posted on 2019-03-15

1820 RBPSponge: genome-wide identification of lncRNAs that sponge RBPs

HafezQorani, S.; Houdjedj, A.; Arici, M.; Said, A.; Kazan, H.

10.1101/566828 — bioinformatics — Posted on 2019-03-15

1821 Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

Felix, J.; Weinhaupl, K.; Chipot, C.; Dehez, F.; Hessel, A.; F. Gauto, D.; Morlot, C.; Abian, O.; Gutsche, I.; Velazquez-Campoy, A.; Schanda, P.; Fraga, H.

10.1101/578260 — biochemistry — Posted on 2019-03-15

1822 Evolution of Phototransduction Genes in Lepidoptera

Macias-Munoz, A.; Rangel Olguin, A. G.; Briscoe, A. D.

10.1101/577031 — evolutionary biology — Posted on 2019-03-15

1823 Selection of a Malignant Subpopulation from a Colorectal Cancer Cell Line

Lai, P.-L.; Chen, T.-C.; Feng, C.-Y.; Lin, H.; Wu, N.; Chen, Y.; Hsiao, M.; Lu, J.; Huang, H.-C.

10.1101/578823 — cancer biology — Posted on 2019-03-15

1824 Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis

Durif, G.; Modolo, L.; Mold, J. E.; Lambert-Lacroix, S.; Picard, F.

10.1101/211938 — bioinformatics — Posted on 2019-03-15

1825 Probing the flavin transfer mechanism in alkanesulfonate monooxygenase system

Dayal, P.; Ellis, H.

10.1101/433839 — biochemistry — Posted on 2019-03-15

1826 Enabling large-scale genome editing by reducing DNA nicking

Smith, C. J.; Castanon, O.; Said, K.; Volf, V.; Khoshakhlagh, P.; Hornick, A.; Ferreira, R.; Wu, C.-T.; Güell, M.; Garg, S.; Myllykallio, H.; Church, G. M.

10.1101/574020 — synthetic biology — Posted on 2019-03-15

1827 1-Methyl-tryptophan enantiomers differently affect the cross- talking between mononuclear and tumor cells and interferon-γ production.

Branquinho, M. S. F.; Silva, M. B. B.; Clara, R. O.; Julio, A. R.; Engler, S. S. M.; Pinto Junior, E.; Campa, A.

10.1101/578369 — pharmacology and toxicology — Posted on 2019-03-15

1828 Dynamics of Mycobacterium tuberculosis Ag85B revealed by sensitive ELISA

Ernst, J. D.; Cornelius, A.; Bolz, M.

10.1101/574996 — microbiology — Posted on 2019-03-15

1829 Genome-Wide Polygenic Risk Scores and prediction of Gestational Diabetes in South Asian Women

Lamri, A.; Mao, S.; Desai, D.; Gupta, M.; Pare, G.; Anand, S. S.

10.1101/574616 — genomics — Posted on 2019-03-15

1830 Dynamic metabolic profiles of marine macroalga Ulva prolifera during fragmentation-induced proliferation

He, Y.; Wang, Y.; Hu, C.; Sun, X.; Li, Y.; Xu, N.

10.1101/578963 — physiology — Posted on 2019-03-15

1831 Cortico-basal white matter alterations occurring in Parkinson’s disease

Isaacs, B.; Trutti, A. C.; Pelzer, E.; Tittgemeyer, M.; Temel, Y.; Forstmann, B.; Keuken, M.

10.1101/576991 — neuroscience — Posted on 2019-03-14

1832 MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus

Cherfils, J.; Galicia, C.; Lhospice, S.; Fernandez Varela, P.; Trapani, S.; Zhang, W.; Navaza, J.; Mignot, T.

10.1101/577387 — microbiology — Posted on 2019-03-14

1833 Genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheep

Banos, G.; Clark, E.; Bush, S.; Dutta, P.; Bramis, G.; Arsenos, G.; Hume, D.; Psifidi, A.

10.1101/577015 — genetics — Posted on 2019-03-14

1834 Damped White Noise Diffusion with Memory for Diffusing Microprobes in Ageing Fibrin Gels

Aure, R. L.; Bernido, C. C.; Bernido, M. V. C.; Bacabac, R. G.

10.1101/576710 — biophysics — Posted on 2019-03-14

1835 Genomes from Bacteria Associated with the Canine Oral Cavity: a Test Case for Automated Genome-Based Taxonomic Assignment

Coil, D. A.; Jospin, G.; Darling, A. E.; Wallis, C.; Davis, I. J.; Harris, S.; Eisen, J. A.; Holcombe, L. J.; O'Flynn, C.

10.1101/577163 — bioinformatics — Posted on 2019-03-14

1836 Hepatoprotective effects of Erythrina abyssinica Lam Ex Dc against Non Alcoholic Fatty Liver Disease in Sprague Dawley Rats

MACHARIA, F.; MWANGI, P. W.; Yenesew, A.; Bukachi, F.; NYAGA, N. M.; Wafula, D. K.

10.1101/577007 — pathology — Posted on 2019-03-14

1837 Sickle cell disease complications: prevalence and resource utilization

Shah, N.; Bhor, M.; Xie, L.; Paulose, J.; Yuce, H.

10.1101/577189 — epidemiology — Posted on 2019-03-14

1838 Swallowing and chewing difficulties are associated with presynaptic dopaminergic dysfunction and greater non-motor symptom burden in early drug-naïve Parkinson’s patients

Polychronis, S.; Dervenoulas, G.; Yousaf, T.; Niccolini, F.; Pagano, G.; Politis, M.

10.1101/577148 — neuroscience — Posted on 2019-03-14

1839 A non-Dicer RNase III and four other novel factors required for RNAi-mediated transposon suppression in the human pathogenic yeast C. neoformans

Burke, J. E.; Longhurst, A. D.; Natarajan, P.; Rao, B.; Liu, S. J.; Sales-Lee, J.; Mortensen, Y.; Moresco, J.; Diedrich, J. K.; Yates, J. R.; Madhani, H. D.

10.1101/577924 — molecular biology — Posted on 2019-03-14

1840 Treatment Failure among People living with HIV taking Antiretroviral Therapy in Ethiopia

Misganie, Y. G.; G/Egziabhier, A.; Zealiyas, K.; Tilahun, R.; Girma, M.; G/Michael, G.; Deressa, T.; Abate, E.; Assefa, Y.

10.1101/577049 — epidemiology — Posted on 2019-03-14

1841 The transcription factor Odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop

Abdusselamoglu, M. D.; Eroglu, E.; Burkard, T. R.; Knoblich, J.

10.1101/576736 — developmental biology — Posted on 2019-03-14

1842 Chemokine signaling links cell cycle progression and cilia formation for left-right symmetry breaking

Liu, J.; Zhu, C.; Ning, G.; Yang, L.; Cao, Y.; Huang, S.; Wang, Q.

10.1101/578351 — developmental biology — Posted on 2019-03-14

1843 Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals

Ulyanova, A. V.; Cottone, C.; Adam, C. D.; Gagnon, K. G.; Cullen, D. K.; Holtzman, T.; Jamieson, B. G.; Koch, P. F.; Chen, H. I.; Johnson, V. E.; Wolf, J. A.

10.1101/400812 — neuroscience — Posted on 2019-03-14

1844 HCF-2 inhibits cell proliferation and activates differentiation-gene expression programs

Gudkova, D.; Dergai, O.; Praz, V.; Herr, W.

10.1101/577890 — molecular biology — Posted on 2019-03-14

1845 Monosodium Iodoacetate delays regeneration and inhibits hypertrophy in skeletal muscle cells in vitro

Rimington, R. P.; Player, D. J.; Martin, N. R. W.; Lewis, M. P.

10.1101/577866 — cell biology — Posted on 2019-03-14

1846 Parallel high-performance computing algorithm to generate FEM-compliant volumetric mesh representations of biomolecules at atomic scale

Lopez, J.; Botello, S.; Herrera, R.; Carrillo-Tripp, M.

10.1101/578658 — biophysics — Posted on 2019-03-14

1847 Maintaining arm control during self-triggered and unpredictable unloading perturbations.

Reschechtko, S.; Johannson, A. S.; Pruszynski, J. A.

10.1101/578450 — neuroscience — Posted on 2019-03-14

1848 An open resource of structural variation for medical and population genetics

Collins, R. L.; Brand, H.; Karczewski, K. J.; Zhao, X.; Alflödi, J.; Khera, A. V.; Francioli, L. C.; Gauthier, L. D.; Wang, H.; Watts, N. A.; Solomonson, M.; O'Donnell-Luria, A.; Baumann, A.; Munshi, R.; Lowther, C.; Walker, M.; Whelan, C.; Huang, Y.; Brookings, T.; Sharpe, T.; Stone, M. R.; Valkanas, E.; Fu, J.; Tiao, G.; Laricchia, K. M.; Stevens, C.; Gupta, N.; Margolin, L.; The Genome Aggregation Database (gnomAD) Productio, ; The gnomAD Consortium, ; Spertus, J. A.; Taylor, K. D.; Lin, H. J.; Rich, S. S.; Post, W.; Chen, Y.-D. I.; Rotter, J. I.; Nusbaum, C.; Philippakis, A.; Lander, E

10.1101/578674 — genomics — Posted on 2019-03-14

1849 Oncogenic hijacking of a developmental transcription factor evokes therapeutic vulnerability for ROS-induction in Ewing sarcoma

Marchetto, A.; Ohmura, S.; Orth, M. F.; Li, J.; Wehweck, F. S.; Knott, M. M. L.; Stein, S.; Saucier, D.; Arrigoni, C.; Gerke, J. S.; Baldauf, M. C.; Musa, J.; Dallmayer, M.; Hoelting, T. L. B.; Moretti, M.; Amatruda, J. F.; Romero-Perez, L.; Cidre-Aranaz, F.; Kirchner, T.; Sannino, G.; Grunewald, T. G. P.

10.1101/578666 — cancer biology — Posted on 2019-03-14

1850 Modeling the stimulatory network in Natural Killer cells

Makaryan, S. Z.; Finley, S. D.

10.1101/395756 — systems biology — Posted on 2019-03-14

1851 The multi-peak adaptive landscape of crocodylomorph body size evolution

Godoy, P. L.; Benson, R. B. J.; Bronzati, M.; Butler, R. J.

10.1101/405621 — paleontology — Posted on 2019-03-14

1852 The accessibility of human centromeric chromatin is modulated by elastic CENP-A nucleosomes

Melters, D. P.; Pitman, M.; Rakshit, T.; Bui, M.; Dimitriadis, E. K.; Papoian, G. A.; Dalal, Y.

10.1101/392787 — biochemistry — Posted on 2019-03-14

1853 Profiling the genome-wide landscape of tandem repeat expansions

Mousavi, N.; Shleizer-Burko, S.; Yanicky, R.; Gymrek, M.

10.1101/361162 — genomics — Posted on 2019-03-14

1854 Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR-Cas9-based approach

von der Heyde, B.; Emmanouilidou, A.; Klingström, T.; Mazzaferro, E.; Vicenzi, S.; Jumaa, S.; Dethlefsen, O.; Snieder, H.; de Geus, E.; Ingelsson, E.; Allalou, A.; Brooke, H. L.; den Hoed, M.

10.1101/385500 — genomics — Posted on 2019-03-14

1855 Sex makes them sleepy: change in host reproductive status induces diapause in a parasitoid population experiencing harsh winters

Tougeron, K.; Brodeur, J.; van Baaren, J.; Renault, D.; Le Lann, C.

10.1101/371385 — ecology — Posted on 2019-03-14

1856 The \"sewing machine\" for minimally invasive neural recording

Hanson, T. L.; Diaz-Botia, C. A.; Kharazia, V.; Maharbiz, M. M.; Sabes, P. N.

10.1101/578542 — neuroscience — Posted on 2019-03-14

1857 Constitutive Siglec-1 expression by human dendritic cell precursors enables HIV-1 replication and transmission

RUFFIN, N.; Gea-Mallorqui, E.; Brouiller, F.; Jouve, M.; Silvin, A.; See, P.; Dutertre, C.-A.; Ginhoux, F.; Benaroch, P.

10.1101/578377 — immunology — Posted on 2019-03-14

1858 Changes in gene expression shift and switch genetic interactions

Li, X.; Lalic, J.; Baeza-Centurion, P.; Dhar, R.; Lehner, B.

10.1101/578419 — genetics — Posted on 2019-03-14

1859 Liver X Receptor β Controls Hepatic Stellate Cell Activation via Hedgehog Signaling

Zhong, L.; Ning, B.; Du, X.; Shengjie, H.; Cai, C.; Zhou, Y.; Deng, L.; Shen, W.

10.1101/577833 — cell biology — Posted on 2019-03-14

1860 Spheroplast-mediated carbapenem tolerance in Gram-negative pathogens

Cross, T.; Ransegnola, B.; Shin, J.-H.; Weaver, A.; Fauntleroy, K.; VanNieuwenhze, M.; Westblade, L.; Dörr, T.

10.1101/578559 — microbiology — Posted on 2019-03-14

1861 Inducible overexpression of zebrafish microRNA-722 suppresses chemotaxis of human neutrophil like cells

Hsu, A.; Liu, S.; Brasseale, K.; Syahirah, R.; Wan, J.; Deng, Q.

10.1101/578583 — immunology — Posted on 2019-03-14

1862 Fog signaling has diverse roles in epithelial morphogenesis in insects

Frey, N.; Benton, M. A.; Nunes da Fonseca, R.; von Levetzow, C.; Stappert, D.; Hakeemi, M. S.; Conrads, K.; Pechmann, M.; Panfilio, K. A.; Lynch, J. A.; Roth, S.

10.1101/578526 — developmental biology — Posted on 2019-03-14

1863 SMAUG: Analyzing single-molecule tracks with nonparametric Bayesian statistics

Karslake, J.; Donarski, E. D.; Shelby, S. A.; Demey, L. M.; DiRita, V. J.; Veatch, S. L.; Biteen, J. S.

10.1101/578567 — biophysics — Posted on 2019-03-14

1864 Uncovering mechanisms of global ocean change effects on the Dungeness crab (Cancer magister) through metabolomics analysis

Trigg, S. A.; McElhany, P.; Maher, M.; Perez, D.; Busch, D. S.; Nichols, K. M.

10.1101/574798 — systems biology — Posted on 2019-03-14

1865 Biological age is a universal marker of aging, stress, and frailty

Pyrkov, T. V.; Fedichev, P. O.

10.1101/578245 — systems biology — Posted on 2019-03-14

1866 Specific type 1 diabetes risk genes underpin age-at-diagnosis and indicate joint defects in immunity, beta-cell fragility and responses to viral infections in early-onset disease.

Inshaw, J.; Cutler, A. J.; Crouch, D. J.; Wicker, L. S.; Todd, J. A.

10.1101/577304 — genetics — Posted on 2019-03-14

1867 A beneficial genomic rearrangement creates multiple versions of calcipressin in C. elegans

Zhao, Y.; Wan, J.; Biliya, S.; Brady, S.; Lee, D.; Andersen, E.; Vannberg, F.; Lu, H.; McGrath, P.

10.1101/578088 — evolutionary biology — Posted on 2019-03-14

1868 HDAC6 promotes PMA-induced megakaryocyte differentiation of K562 cells by regulating ROS levels via NOX4 and repressing Glycophorin A

Kummari, G.; Gutti, R. K.; Kalle, A. M.

10.1101/578096 — developmental biology — Posted on 2019-03-14

1869 Dysregulated wild-type cell division at the interface between host and oncogenic epithelium

Moruzzi, M.; Nestor-Bergmann, A.; Brennan, K.; Woolner, S.

10.1101/578146 — cell biology — Posted on 2019-03-14

1870 Differential effects of two HDAC inhibitors with distinct concomitant DNA hypermethylation or hypomethylation in breast cancer cells

Kalle, A. M.; Wang, Z.

10.1101/578062 — cancer biology — Posted on 2019-03-14

1871 The Antagonism of Folate Receptor by the Integrase Inhibitor Dolutegravir

Cabrera, R. M.; Souder, J. P.; Steele, J. W.; Yeo, L.; Tukeman, G.; Gorelick, D. A.; Finnell, R. H.

10.1101/576272 — pharmacology and toxicology — Posted on 2019-03-14

1872 Cell type-specific monoclonal antibody cross-reactivity screening in non-human primates and development of comparative immunophenotyping panels for CyTOF

Bjornson-Hooper, Z. B.; Fragiadakis, G. K.; Spitzer, M. H.; Madhireddy, D.; Hu, K.; Lundsten, K.; Nolan, G. P.

10.1101/577759 — immunology — Posted on 2019-03-14

1873 Quantifying and understanding well-to-well contamination in microbiome research

Minich, J. J.; Sanders, J.; Amir, A.; Humphrey, G.; Gilbert, J. A.; Knight, R.

10.1101/577718 — genomics — Posted on 2019-03-14

1874 Computational comparison of developmental cell lineage trees by alignments

Yuan, M.; Yang, X.; Lin, J.; Cao, X.; Chen, F.; Zhang, X.; Li, Z.; Zheng, G.; Wang, X.; Chen, X.; Yang, J.-R.

10.1101/577809 — bioinformatics — Posted on 2019-03-14

1875 A rapid method to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis at low pH

Early, J.; Mullen, S.; Parish, T.

10.1101/578195 — microbiology — Posted on 2019-03-14

1876 Comparative Analysis of Electrostatic Models for Ligand Docking

Sartori, G. R.; Nascimento, A. S.

10.1101/577643 — biophysics — Posted on 2019-03-14

1877 Scalable methods for analyzing and visualizing phylogenetic placement of metagenomic samples

Czech, L.; Stamatakis, A.

10.1101/346353 — bioinformatics — Posted on 2019-03-14

1878 Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects

Klicznik, M. M.; Morawski, P. A.; Höllbacher, B.; Varkhande, S.; Motley, S.; Kuri-Cervantes, L.; Goodwin, E.; Rosenblum, M. D.; Long, S. A.; Brachtl, G.; Duhen, T.; Betts, M.; Campbell, D.; Gratz, I. K.

10.1101/361758 — immunology — Posted on 2019-03-14

1879 Soil salinity inhibits plant shade avoidance

Hayes, S.; Pantazopoulou, C. K.; van Gelderen, K.; Reinen, E.; Tween, A.; Sharma, A.; de Vries, M.; Prat, S.; Schuurink, R.; Testerink, C.; Pierik, R.

10.1101/289124 — plant biology — Posted on 2019-03-14

1880 Non-coding AUG circRNAs constitute an abundant and conserved subclass of circles

Stagsted, L. V. W.; Nielsen, K. M.; Daugaard, I.; Hansen, T. B.

10.1101/328104 — molecular biology — Posted on 2019-03-14

1881 Toxicokinetics of citreoviridin in vivo and in vitro.

Uchiyama, Y.; Takino, M.; Noguchi, M.; Shiratori, N.; Sugita-Konishi, Y.

10.1101/578302 — pharmacology and toxicology — Posted on 2019-03-14

1882 Ultra-widefield fluorescein angiography findings in patients with multiple retinal holes.

Baek, J.; Jung, B.; Kwon, H.; Jeon, S.

10.1101/578328 — neuroscience — Posted on 2019-03-14

1883 NET-prism enables RNA polymerase-dedicated transcriptional interrogation at nucleotide resolution

Mylonas, C.; Tessarz, P.

10.1101/246827 — genomics — Posted on 2019-03-14

1884 Relationship between ocean area and incidence of anthropogenic debris ingested by longnose lancetfish (Alepisaurus ferox)

UCHIDA, K.; Kuroda, M.; Miyamoto, Y.; Hagita, R.; Shiode, D.; Joshima, H.; Nemoto, M.; Hamada, H.; Yamada, Y.; Takada, H.; Yamashita, R.; Fukunaga, K.

10.1101/578310 — ecology — Posted on 2019-03-14

1885 Short-term effects of hurricanes Maria and Irma on forest birds of Puerto Rico

Lloyd, J. D.; Rimmer, C. C.; Salguero Faria, J.

10.1101/578336 — ecology — Posted on 2019-03-14

1886 Short-time fractal analysis of biological autoluminescence

Dlask, M.; Kukal, J.; Sovka, P.; Poplova, M.; Cifra, M.

10.1101/578286 — biophysics — Posted on 2019-03-14

1887 CHOP: Haplotype-aware path indexing in population graphs

Mokveld, T. O.; Linthorst, J.; Al-Ars, Z.; Holstege, H.; Reinders, M.

10.1101/305268 — bioinformatics — Posted on 2019-03-14

1888 Automated 3D Axonal Morphometry of White Matter

Abdollahzadeh, A.; Belevich, I.; Jokitalo, E.; Tohka, J.; Sierra, A.

10.1101/239228 — neuroscience — Posted on 2019-03-14

1889 Drought Affects the Antioxidant System and Stomatal Aperture in Zanthoxylum bungeanum Maxim.

Fei, X.; Hu, H.; Li, J.; Liu, Y.; Wei, A.

10.1101/578294 — cell biology — Posted on 2019-03-14

1890 A decade of empirical research on research integrity: what have we (not) looked at?

Aubert Bonn, N.; Pinxten, W.

10.1101/567263 — scientific communication and education — Posted on 2019-03-14

1891 Cdc14 phosphatase ensures resolution of aberrant meiotic recombination outcomes partly through activating Yen1/GEN1

Pascual-Silva, C.; Strouhalova, K.; Garside, G. B.; Arter, M.; Alvarez-Melo, D.; Bermejo, T.; San-Segundo, P.; Matos, J.; Geymonat, M.; Carballo, J. A.

10.1101/571083 — genetics — Posted on 2019-03-14

1892 The Endocrine and Metabolic Response in Male Survivors of Major Trauma

Foster, M. A.; Taylor, A. E.; Hill, N. E.; Bentley, C.; Bishop, J.; Bion, J. F.; Fallowfield, J. L.; Woods, D. R.; Bancos, I.; Midwinter, M.; Lord, J.; Arlt, W.

10.1101/577502 — physiology — Posted on 2019-03-14

1893 Soft tissue calcification in mice is governed by fetuin-A, pyrophosphate and magnesium

Babler, A.; Schmitz, C.; Buescher, A.; Herrmann, M.; Gremse, F.; Gorgels, T. G.; Floege, J.; Jahnen-Dechent, W.

10.1101/577239 — physiology — Posted on 2019-03-14

1894 Rapid invariant encoding of scene layout in human OPA

Henriksson, L.; Mur, M.; Kriegeskorte, N.

10.1101/577064 — neuroscience — Posted on 2019-03-14

1895 Identifying the most influential features of neural population responses for information encoding and behavior

Nogueira, R.; Peltier, N. E.; Anzai, A.; DeAngelis, G. C.; Martinez-Trujillo, J.; Moreno-Bote, R.

10.1101/577379 — neuroscience — Posted on 2019-03-14

1896 Expression of ppsD, a gene involved in synthesis of Mycobacterium tuberculosis virulence factor PDIM, reflects treatment response in pulmonary tuberculosis patients

Sriraman, K.; Kekane, R.; Shah, D.; Saranath, D.; Mistry, N.

10.1101/576470 — microbiology — Posted on 2019-03-14

1897 Stress-Induced Transcriptional Memory Accelerates Promoter-Proximal Pause-Release and Decelerates Termination over Mitotic Divisions

Vihervaara, A.; Mahat, D. B.; Himanen, S. V.; Blom, M. A. H.; Lis, J. T.; Sistonen, L.

10.1101/576959 — molecular biology — Posted on 2019-03-14

1898 OVOL2 induces mesenchymal-to-epithelial transition in fibroblasts and enhances reprogramming to epithelial lineages

Watanabe, K.; Liu, Y.; Noguchi, S.; Murray, M.; Chang, J.-C.; Kishima, M.; Nishimura, H.; Hashimoto, K.; Minoda, A.; Suzuki, H.

10.1101/577692 — cell biology — Posted on 2019-03-14

1899 The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology

Hahn, I.; Voelzmann, A.; Liew, Y.-T.; Costa-Gomes, B.; Prokop, A.

10.1101/577320 — cell biology — Posted on 2019-03-14

1900 3D rotational motion of an endocytic vesicle on a complex microtubule network in a living cell

Higuchi, H.; Lee, S.

10.1101/576702 — biophysics — Posted on 2019-03-14

1901 Structural basis of internal peptide recognition by PDZ domains using molecular dynamics simulations

Sain, N.; Mohanty, D.

10.1101/575233 — bioinformatics — Posted on 2019-03-14

1902 Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana - Botrytis cinerea pathosystem

Soltis, N. E.; Zhang, W.; Corwin, J. A.; Atwell, S.; Kliebenstein, D. J.

10.1101/577585 — plant biology — Posted on 2019-03-14

1903 Spatially modulated alpha-band activity does not mediate tactile remapping and fast overt orienting behavior

Ossandon, J. P.; König, P.; Heed, T.

10.1101/576850 — neuroscience — Posted on 2019-03-14

1904 Nonlinear mixed selectivity supports reliable neural computation

Johnston, W. J.; Palmer, S. E.; Freedman, D. J.

10.1101/577288 — neuroscience — Posted on 2019-03-14

1905 Ten-year retrospective analysis of Acinetobacter baumannii clinical isolates reveals a proportionately large, non-nosocomial, multidrug-resistant endemic reservoir

Calix, J. J.; Burnham, J. P.; Feldman, M. F.

10.1101/576868 — microbiology — Posted on 2019-03-14

1906 Land-use and related pressures have reduced biotic integrity more on islands than on mainlands

Sanchez Ortiz, K.; Gonzalez, R.; De Palma, A.; Newbold, T.; Hill, S.; Tylianakis, J.; Borger, L.; Lysenko, I.; Purvis, A.

10.1101/576546 — ecology — Posted on 2019-03-14

1907 Planar cell polarity in the C. elegans embryo emerges by differential retention of aPARs at cell-cell contacts

Dutta, P.; Odedra, D.; Pohl, C.

10.1101/576777 — cell biology — Posted on 2019-03-14

1908 Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography

Weinert, T.; Skopintsev, P.; James, D.; Dworkowski, F.; Panepucci, E.; Kekilli, D.; Furrer, A.; Brünle, S.; Mous, S.; Ozerov, D.; Nogly, P.; Wang, M.; Standfuss, J.

10.1101/576629 — biophysics — Posted on 2019-03-14

1909 Transcriptomic analysis of the BDNF-induced JAK/STAT pathway in neurons: a window into epilepsy-associated gene expression

Hixson, K. M.; Cogswell, M. C.; Brooks-Kayal, A. R.; Russek, S. J.

10.1101/577627 — neuroscience — Posted on 2019-03-14

1910 Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan

Reine, J.; Carniel, B. F.; Solorzano, C.; Mitsi, E.; Pojar, S.; Nikolau, E.; German, E. L.; Hyder-Wright, A. D.; Hill, H.; Hales, C.; Brown, L.; Horsley, V.; Hughes, L.; Zaidi, S.; Connor, V.; Morton, B.; Collins, A. M.; Rylance, J.; Adler, H.; McNamara, P. S.; Ferreira, D. M.; Jochems, S. P.

10.1101/576744 — immunology — Posted on 2019-03-14

1911 Optimal strategies for pirate phage spreading

Mitarai, N.

10.1101/576587 — ecology — Posted on 2019-03-14

1912 Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

Lee, Y.; Wiriyasermkul, P.; Jin, C.; Quan, L.; Ohgaki, R.; Okuda, S.; Kusakizako, T.; Nishizawa, T.; Oda, K.; Ishitani, R.; Yokoyama, T.; Nakane, T.; Shirouzu, M.; Endou, H.; Nagamori, S.; Kanai, Y.; Nureki, O.

10.1101/577551 — biochemistry — Posted on 2019-03-14

1913 Facilitation and inhibition of firing activity and N-methyl-D-aspartate-evoked responses of CA1 hippocampal pyramidal cells by alpha7 nicotinic acetylcholine receptor selective compounds in vivo

Bali, Z. K.; Nagy, L. V.; Budai, D.; Hernadi, I.

10.1101/576520 — neuroscience — Posted on 2019-03-14

1914 Dynamic network properties of the interictal brain determine whether seizures appear focal or generalised

Woldman, W.; Schmidt, H.; Abela, E.; Chowdhury, F. A.; Pawley, A. D.; Jewell, S.; Richardson, M. P.; Terry, J. R.

10.1101/576785 — neuroscience — Posted on 2019-03-14

1915 Ibuprofen-mediated potential inhibition of biofilm development and quorum sensing in Pseudomonas aeruginosa

Dai, L.; Wu, T.-q.; Wang, Z.-h.; Yuan, R.; Ding, Y.; Zhang, W.-c.; Chu, S. p.; Ju, S.; Yu, J.

10.1101/576447 — microbiology — Posted on 2019-03-14

1916 Iron-sulfur cluster repair contributes to Y. pseudotuberculosis survival within deep tissues

Davis, K. M.; Krupp, J.; Clark, S.; Isberg, R. R.

10.1101/576454 — microbiology — Posted on 2019-03-14

1917 CTCF and Cohesin link sex-biased distal regulatory elements to sex-biased gene expression in mouse liver

Matthews, B. J.; Waxman, D. J.

10.1101/577577 — genomics — Posted on 2019-03-14

1918 Natural allelic variations of Saccharomyces cerevisiae impact stuck fermentation due to the combined effect of ethanol and temperature; a QTL-mapping study.

Marullo, P.; Durrens, P.; Peltier, E.; Bernard, M.; Mansour, C.; Dubourdieu, D.

10.1101/576835 — genetics — Posted on 2019-03-14

1919 Low marine food levels mitigate high migration costs in anadromous populations

Chaparro-Pedraza, P. C.; De Roos, A.

10.1101/577353 — ecology — Posted on 2019-03-14

1920 Abrogating ALIX interactions results in stuttering of the ESCRT machinery

Gupta, S.; Bendjennat, M.; Saffarian, S.

10.1101/576926 — cell biology — Posted on 2019-03-14

1921 Luminal Calcification of the Microvasculature in Fetuin-A Deficient Mice Leads to Premature Aging and Death

Herrmann, M.; Babler, A.; Moshkova, I.; Gremse, F.; Kiessling, F.; Kusebauch, U.; Nelea, V.; Kramann, R.; Moritz, R. L.; McKee, M. D.; Jahnen-Dechent, W.

10.1101/577098 — physiology — Posted on 2019-03-14

Stark, S. M.; Frithsen, A.; Stark, C. E.

10.1101/577361 — neuroscience — Posted on 2019-03-14

1923 Direct proteolytic control of an extracytoplasmic function RNA polymerase sigma factor

Bilyk, B.; Kim, S.; BAKER, T.; Seipke, R. F.

10.1101/576462 — microbiology — Posted on 2019-03-14

1924 Discovery of small alarmone synthetases and their inhibitors as toxin-antitoxin loci

Jimmy, S.; Saha, C. K.; Stavropoulos, C. G.; Garcia-Pino, A.; Hauryliuk, V.; Atkinson, G. C.

10.1101/575399 — microbiology — Posted on 2019-03-14

1925 Epistasis detection and modeling for genomic selection in cowpea (Vigna unguiculata. L. Walp.)

Olatoye, M. O.; Hu, Z.; Aikpokpodion, P. O.

10.1101/576819 — genetics — Posted on 2019-03-14

1926 Population histories of the United States revealed through fine-scale migration and haplotype analysis

Dai, C. L.; Vazifeh, M. M.; Yeang, C.-H.; Tachet, R.; Vilar, M. G.; Daly, M. J.; Ratti, C.; Martin, A. R.

10.1101/577411 — genetics — Posted on 2019-03-14

1927 Common variants in OSMR contribute to carotid plaque vulnerability

van Keulen, D.; van Koeverden, I. D.; Boltjes, A.; Princen, H. M. G.; van Gool, A. J.; de Borst, G. J.; Asselbergs, F. W.; Tempel, D.; Pasterkamp, G.; van der Laan, S. W.

10.1101/576793 — genetics — Posted on 2019-03-14

1928 Prenatal diagnosis of HNF1B-associated renal cysts: Need to differentiate intragenic variants from 17q12 microdeletion syndrome?

Vasileiou, G.; Hoyer, J.; Thiel, C. T.; Schaefer, J.; Zapke, M. Z.; Krumbiegel, M.; Kraus, C.; Zweier, M.; Uebe, S.; Ekici, A. B.; Schneider, M.; Wiesener, M.; Rauch, A.; Faschingbauer, F.; Reis, A.; Zweier, C.; Popp, B.

10.1101/576918 — genetics — Posted on 2019-03-14

1929 Molecular biogeography and host relations of a parasitoid fly

Gray, D. A.; Kunerth, H. D.; Zuk, M.; Cade, W. H.; Balenger, S. L.

10.1101/576892 — evolutionary biology — Posted on 2019-03-14

1930 Botswana’s wildlife losing ground as Kalahari Wildlife Management Areas (WMAs) are dezoned for livestock expansion

Keeping, D.; Kashe, N.; Langwane, H.; Sebati, P.; Molese, N.; Gielen, M.-C.; Keitsile-Barungwi, A.; Khukwe, Q.; Brahman, !Nate

10.1101/576496 — ecology — Posted on 2019-03-14

1931 A role for liquid-liquid phase separation in ESCRT-mediated nuclear envelope reformation.

von Appen, A.; Lajoie, D.; Johnson, I. E.; Trnka, M.; Pick, S. M.; Burlingame, A. L.; Ullman, K. S.; Frost, A.

10.1101/577460 — cell biology — Posted on 2019-03-14

1932 A HaloTag-TEV genetic cassette for mechanical phenotyping of native proteins

Rivas-Pardo, J. A.; Li, Y.; Martonfalvi, Z.; Tapia-Rojo, R.; Unger, A.; Fernandez-Trasancos, A.; Herrero-Galan, E.; Velazquez-Carreras, D.; Linke, W. A.; Fernandez, J. M.; Alegre-Cebollada, J.

10.1101/577445 — biophysics — Posted on 2019-03-14

1933 Supramodal sentence processing in the human brain: fMRI evidence for the influence of syntactic complexity in more than 200 participants

Udden, J.; Hulten, A.; Schoffelen, J. M.; Lam, N.; Harbusch, K.; van den Bosch, A.; Kempen, G.; Petersson, K. M.; Hagoort, P.

10.1101/576769 — neuroscience — Posted on 2019-03-14

1934 Vestibular modulation of multisensory integration during actual and vicarious tactile stimulation

Ponzo, S.; Kirsch, L. P.; Fotopoulou, A.; Jenkinson, P. M.

10.1101/576611 — neuroscience — Posted on 2019-03-14

1935 Characterization of coral-associated microbial aggregates (CAMAs) within tissues of the coral Acropora hyacinthus

Wada, N.; Ishimochi, M.; Matsui, T.; Pollock, F. J.; Tang, S.-L.; Ainsworth, T. D.; Willis, B. L.; Mano, N.; Bourne, D. G.

10.1101/576488 — microbiology — Posted on 2019-03-14

1936 Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2

Lau-Corona, D.; Bae, W. K.; Hennighausen, L.; Waxman, D. J.

10.1101/577056 — genomics — Posted on 2019-03-14

1937 Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression

Hafemeister, C.; Satija, R.

10.1101/576827 — genomics — Posted on 2019-03-14

1938 Germ Granules Functions are Memorized by Transgenerationally Inherited Small RNAs

Lev, I.; Toker, I. A.; Mor, Y.; Nitzan, A.; Weintraub, G.; Bhonkar, O.; Ben Shushan, I.; Seroussi, U.; Claycomb, J.; Gingold, H.; Zaidel-Bar, R.; Rechavi, O.

10.1101/576934 — genetics — Posted on 2019-03-14

1939 Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish

Grzegorski, S. J.; Hu, Z.; Liu, Y.; Yu, X.; Ferguson, A. C.; Madarati, H.; Friedmann, A. P.; Reyon, D.; Kim, P. Y.; Kretz, C. A.; Joung, J. K.; Shavit, J. A.

10.1101/576140 — genetics — Posted on 2019-03-14

1940 Species specificity and intraspecific variation in the chemical profiles of Heliconius butterflies across a large geographic range

Darragh, K.; Montejo-Kovacevich, G.; Kozak, K. M.; Morrison, C. R.; Figueiredo, C. M. E.; Ready, J. S.; Salazar, C.; Linares, M.; Byers, K. J. R. P.; Merrill, R. M.; McMillan, W. O.; Schulz, S.; Jiggins, C. D.

10.1101/573469 — evolutionary biology — Posted on 2019-03-14

1941 Sex-specific population dynamics and demography of capercaillie (Tetrao urogallus L.) in a patchy environment

Augustine, B.; Kery, M.; Olano Marin, J.; Mollet, P.; Pasinelli, G.; Sutherland, C.

10.1101/576876 — ecology — Posted on 2019-03-14

1942 A core microbiota of the plant-earthworm interaction conserved across soils

Jacquiod, S.; Puga-Freitas, R.; Spor, A.; Mounier, A.; Monard, C.; Mougel, C.; Philippot, L.; Blouin, M.

10.1101/571240 — ecology — Posted on 2019-03-14

1943 DNA barcode reference libraries for the monitoring of aquatic biota in Europe: Gap-analysis and recommendations for future work

Weigand, H.; Beermann, A. J.; Ciampor, F.; Costa, F. O.; Csabai, Z.; Duarte, S.; Geiger, M. F.; Grabowski, M.; Rimet, F.; Rulik, B.; Strand, M.; Szucsich, N.; Weigand, A. M.; Willassen, E.; Wyler, S. A.; Bouchez, A.; Borja, A.; Ciamporova-Zat'ovicova, Z.; Ferreira, S.; Dijkstra, K.; Eisendle, U.; Freyhof, J.; Gadawski, P.; Graf, W.; Haegerbaeumer, A.; van der Hoorn, B. B.; Japoshvili, B.; Keresztes, L.; Keskin, E.; Leese, F.; Macher, J.; Mamos, T.; Paz, G.; Pesic, V.; Pfannkuchen, D. M.; Pfannkuchen, M. A.; Price, B. W.; Rinkevich, B.; Teixeira, M. A. L.; Varbiro, G.; Ekrem, T.

10.1101/576553 — ecology — Posted on 2019-03-14

1944 Environmental change effects on life history traits and population dynamics of anadromous fishes

Chaparro-Pedraza, P. C.; De Roos, A.

10.1101/577262 — ecology — Posted on 2019-03-14

1945 pHluo_M153R-CD63, a bright, versatile live cell reporter of exosome secretion and uptake, reveals pathfinding behavior of migrating cells

Sung, B. H.; Pelletier, R. J.; Weaver, A. M.

10.1101/577346 — cell biology — Posted on 2019-03-14

1946 An immunoevasive strategy through clinically-relevant pan cancer genomic and transcriptomic alterations of JAK-STAT signaling components

Chang, W. H.; Lai, A. G.

10.1101/576645 — cancer biology — Posted on 2019-03-14

1947 TANGO1 regulates membrane tension to mediate procollagen export

Raote, I.; Garcia-Parajo, M. F.; Malhotra, V.; Campelo, F.

10.1101/576637 — biophysics — Posted on 2019-03-14

1948 An open-source and low-cost feeding system for zebrafish facilities

Tangara, A.; Paresys, G.; Bouallague, F.; Cabirou, Y.; Fodor, J.; Llobet, V.; Sumbre, G.

10.1101/558205 — neuroscience — Posted on 2019-03-14

1949 A smart polymer for sequence-selective binding, pulldown and release of DNA targets

Krieg, E.; Gupta, K.; Dahl, A.; Lesche, M.; Boye, S.; Lederer, A.; Shih, W. M.

10.1101/573030 — molecular biology — Posted on 2019-03-14

1950 First hybrid complete genome of Aeromonas veronii reveals chromosome-mediated novel structural variant mcr-3.19 from human clinical specimen

Devanga Ragupathi, N. K.; Muthuirulandi Sethuvel, D. P.; Anandan, S.; Murugan, D.; Asokan, K.; Neethi Mohan, R. G.; Vasudevan, K.; D, T. K.; C, G. P. D.; Veeraraghavan, B.

10.1101/576421 — microbiology — Posted on 2019-03-14

1951 The obese liver environment mediates conversion of NK cells to a less cytotoxic ILC1-like phenotype

Cuff, A. O.; Sillito, F.; Dertschnig, S.; Hall, A.; Luong, T.; Chakraverty, R.; Male, V.

10.1101/576538 — immunology — Posted on 2019-03-14

1952 Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance

Bansept, F.; Marrec, L.; Bitbol, A.-F.; Loverdo, C.

10.1101/577510 — evolutionary biology — Posted on 2019-03-14

1953 Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis.

Phillips, H. M.; Stothard, C. A.; Shaikh Qureshi, W. M.; Kousa, A. I.; Briones-Leon, A.; Khasawneh, R.; Sanders, R.; Mazotta, S.; Dodds, R.; Seidel, K.; Bates, T.; Nakatomi, M.; Cockell, S.; Schneider, J. E.; Mohun, T. J.; Maehr, R.; Kist, R.; Peters, H.; Bamforth, S. D.

10.1101/576660 — developmental biology — Posted on 2019-03-14

1954 Plasma Circular RNA Panel to Diagnose Hepatitis B Virus-Related Hepatocellular Carcinoma

Zhou, W.-p.; Yu, J.; Wang, M.-c.; Ding, W.-b.; Guo, X.-g.; Xu, J.; Xu, Q.-g.; Yang, Y.; Sun, S.-h.; Liu, J.; Qin, L.-x.; Liu, H.; Yang, F.

10.1101/576751 — cancer biology — Posted on 2019-03-14

1955 The sequence of the extruded non-template strand determines the architecture of R-loops.

Carrasco-Salas, Y.; Malapert, A.; Sulthana, S.; Molcrette, B.; Chazot-Franguiadakis, L.; Bernard, P.; Chedin, F.; Faivre-Moskalenko, C.; Vanoosthuyse, V.

10.1101/576561 — biophysics — Posted on 2019-03-14

1956 MicroRNA-transcriptome networks in whole blood and monocytes of women undergoing preterm labor

Paquette, A. G.; Shynlova, O.; Wu, X.; Kibschull, M.; Wang, K.; Price, N. D.; Lye, S.

10.1101/575944 — systems biology — Posted on 2019-03-14

1957 Evaluating artesunate-amodiaquine deployment, efficacy and safety: an in silico pharmacological model

Hong, K. B.; Hastings, I.; Kay, K.; Hodel, E. M.

10.1101/567008 — pharmacology and toxicology — Posted on 2019-03-14

1958 White Matter Hyperintensity Quantification in Large-Scale Clinical Acute Ischemic Stroke Cohorts - The MRI-GENIE Study

Schirmer, M. D.; Dalca, A. V.; Sridharan, R.; Giese, A.-K.; Donahue, K. L.; Nardin, M. J.; Mocking, S. J. T.; McIntosh, E. C.; Frid, P.; Wasselius, J.; Cole, J. W.; Holmegaard, L.; Jern, C.; Jimenez-Conde, J.; Lemmens, R.; Lindgren, A. G.; Meschia, J. F.; Roquer, J.; Rundek, T.; Sacco, R. L.; Schmidt, R.; Sharma, P.; Slowik, A.; Thijs, V.; Woo, D.; Vagal, A.; Xu, H.; Kittner, S. J.; McArdle, P. F.; Mitchell, B. D.; Rosand, J.; Worrall, B. B.; Wu, O.; Golland, P.; Rost, N. S.

10.1101/552844 — neuroscience — Posted on 2019-03-13

1959 Short-term depression and long-term plasticity together tune sensitive range of synaptic plasticity

Deperrois, N.; Graupner, M.

10.1101/565291 — neuroscience — Posted on 2019-03-13

1960 A gravity-based three-dimensional compass in the mouse brain

Angelaki, D. E.; Ng, J.; Abrego, A. M.; Cham, H. X.; Dickman, D.; Laurens, J.

10.1101/570382 — neuroscience — Posted on 2019-03-13

1961 Temporal dynamics of inhalation-linked activity across defined subpopulations of mouse olfactory bulb neurons imaged in vivo.

Short, S. M.; Wachowiak, M.

10.1101/558999 — neuroscience — Posted on 2019-03-13

1962 Domain-specific working memory, but not dopamine-related genetic variability, shapes reward-based motor learning

Holland, P.; Codol, O.; Oxley, E.; Taylor, M.; Hamshere, E.; Joseph, S.; Huffer, L.; Galea, J. M.

10.1101/524900 — neuroscience — Posted on 2019-03-13

1963 Brain meta-state transitions demarcate spontaneous thoughts in movie-viewing and resting cognition

Tseng, J.; Poppenk, J.

10.1101/576298 — neuroscience — Posted on 2019-03-14

1964 Mapping Histone Modifications in Low Cell Number and Single Cells Using Antibody-guided Chromatin Tagmentation (ACT-seq)

Carter, B.; Ku, W. L.; Tang, Q.; Kang, J. Y.; Zhao, K.

10.1101/571208 — genomics — Posted on 2019-03-13

1965 A Bayesian Approach for Inferring the Impact of a Discrete Character on Rates of Continuous-Character Evolution in the Presence of Background Rate Variation

May, M. R.; Moore, B. R.

10.1101/576207 — evolutionary biology — Posted on 2019-03-13

1966 Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics

Sorensen, C. S.; Kjaergaard, M.

10.1101/577536 — biophysics — Posted on 2019-03-14

1967 Metabolic network reductions

Tefagh, M.; Boyd, S. P.

10.1101/499251 — systems biology — Posted on 2019-03-13

1968 Effect of topical soluble epoxide hydrolase inhibition in a preclinical diabetic wound healing model.

Reisdorf, W.; Rajpal, N.; Gehman, A.; Jain, P.; Burgert, M.; Sonti, S.; Agarwal, P.; Rajpal, D.

10.1101/571984 — physiology — Posted on 2019-03-13

1969 Renal Localization of Plasmodium vivax and Zoonotic Monkey Parasite Plasmodium Knowlesi in Malaria Associated Acute Kidney Injury

Acharya, P.; Pramanik, A.; Kaur, C.; Sinha, K.; Dinda, A.; Sankar, J.; Bagga, A.; Agarwal, S.; Sinha, A.; Singh, G.

10.1101/544726 — microbiology — Posted on 2019-03-13

1970 Structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma

Lopez, G.; Conkrite, K. L.; Doepner, M.; Rathi, K. S.; Modi, A.; Vaksman, Z.; Farra, L. M.; Hyson, E.; Noureddine, M.; Wei, J. S.; Smith, M. A.; Asgharzadeh, S.; Seeger, R. C.; Khan, J.; Guidry Auvil, J. M.; Gerhard, D. S.; Maris, J. M.; Diskin, S. J.

10.1101/572248 — cancer biology — Posted on 2019-03-13

1971 A distributed lattice of aligned atoms exists in a protein structure: A hierarchical clustering study of displacement parameters in bovine trypsin

Ahlberg Gagner, V.; Lundholm, I.; Garcia-Bonete, M.-J.; Rodilla, H.; Friedman, R.; Zhaunerchyk, V.; Bourenkov, G.; Schneider, T.; Stake, J.; Katona, G.

10.1101/475889 — biophysics — Posted on 2019-03-13

1972 Persistent anti-heart autoimmunity causes cardiomyocyte damage in chronic heart failure.

Sintou, A.; el Rifai, S.; Mansfield, C.; Rothery, S.; Sanchez Alonso, J. L.; Narodden, S.; Sharma, K.; Ferraro, E.; Hasham, M. G.; Swiatlowska, P.; Harding, S. E.; Rosenthal, N.; Gorelik, J.; Sattler, S.

10.1101/542597 — immunology — Posted on 2019-03-13

1973 High-density spatial transcriptomics arrays for in situ tissue profiling

Vickovic, S.; Eraslan, G.; Salmen, F.; Klughammer, J.; Stenbeck, L.; Aijo, T.; Bonneau, R.; Fernandez Navarro, J.; Bergenstraahle, L.; Gould, J.; Ronaghi, M.; Frisen, J.; Lundeberg, J.; Regev, A.; Staahl, P. L.

10.1101/563338 — genomics — Posted on 2019-03-13

1974 Self-reported Health is Related to Body Height and Waist Circumference in Rural Indigenous and Urbanized Latin-American Populations

Leongomez, J. D.; Sanchez, O. R.; Vasquez-Amezquita, M.; Valderrama, E.; Castellanos-Chacon, A.; Morales-Sanchez, L.; Nieto, J.; Gonzalez-Santoyo, I.

10.1101/562942 — evolutionary biology — Posted on 2019-03-13

1975 A Quasi Birth-and-Death Model For Tumor Recurrence

Santana, L. M.; Ganesan, S.; Bhanot, G.

10.1101/551770 — cancer biology — Posted on 2019-03-13

1976 Qtlizer: comprehensive QTL annotation of GWAS results

Munz, M.; Wohlers, I.; Simon, E.; Busch, H.; Schaefer, A. S.; Erdmann, J.

10.1101/495903 — bioinformatics — Posted on 2019-03-13

1977 Confidence as a priority signal

Aguilar-Lleyda, D.; Lemarchand, M.; de Gardelle, V.

10.1101/480350 — neuroscience — Posted on 2019-03-13

1978 Genotype-phenotype relationships in children with Copy Number Variants associated with high neuropsychiatric risk: Findings from the case-control IMAGINE-ID cohort in the United Kingdom

Chawner, S.; Owen, M.; Holmans, P.; Raymond, L.; Skuse, D.; Hall, J.; van den Bree, M.

10.1101/535708 — genomics — Posted on 2019-03-13

1979 Adaptation and the Parliament of Genes

Scott, T. W.; West, S. A.

10.1101/526970 — evolutionary biology — Posted on 2019-03-13

1980 Exploring neighborhoods in large metagenome assembly graphs reveals hidden sequence diversity

Brown, C. T.; Moritz, D.; O'Brien, M.; Reidl, F.; Reiter, T.; Sullivan, B.

10.1101/462788 — bioinformatics — Posted on 2019-03-13

1981 Valid post-clustering differential analysis for single-cell RNA-Seq

Zhang, J. M.; Kamath, G. M.; Tse, D. N.

10.1101/463265 — bioinformatics — Posted on 2019-03-13

1982 A high-throughput fluorescence-based assay for the detection of petroleum hydrocarbon degrading bacteria

French, K. E.; Terry, N.

10.1101/498345 — microbiology — Posted on 2019-03-13

1983 Dysregulated Oscillatory Connectivity in the Visual System in Autism Spectrum Disorder

Seymour, R. A.; Rippon, G.; Gooding-Williams, G.; Schoffelen, J.-M.; Kessler, K.

10.1101/440586 — neuroscience — Posted on 2019-03-13

1984 Attention explores space periodically at the theta frequency

Senoussi, M.; Moreland, J. C.; Busch, N. A.; Dugue, L.

10.1101/443341 — neuroscience — Posted on 2019-03-13

1985 HIV/AIDS treatment failure and its associated factors in Ethiopia: Systematic review and meta-analysis

Endalamaw, A.; Mekonnen, M.; Geremew, D.; Ambaw, F.; Tesera, H.; Habtewold, T. D.

10.1101/440743 — epidemiology — Posted on 2019-03-13

1986 Nanopore formation in the cuticle of an insect olfactory sensillum

Ando, T.; Sekine, S.; Inagaki, S.; Misaki, K.; Badel, L.; Moriya, H.; Sami, M. M.; Itakura, Y.; Chihara, T.; Kazama, H.; Yonemura, S.; Hayashi, S.

10.1101/444729 — developmental biology — Posted on 2019-03-13

1987 uORF-Tools - Workflow for the determination of translation-regulatory upstream open reading frames

Scholz, A.; Eggenhofer, F.; Gelhausen, R.; Grüning, B.; Zarnack, K.; Brüne, B.; Backofen, R.; Schmid, T.

10.1101/415018 — bioinformatics — Posted on 2019-03-13

1988 The intrinsic and regulated proteomes of barley seeds in response to fungal infection

Kerr, E. D.; Phung, T. K.; Caboche, C. H.; Fox, G. P.; Platz, G. J.; Schulz, B. L.

10.1101/445916 — biochemistry — Posted on 2019-03-13

1989 Centromeric CENP-A loading requires accurate mitotic timing, which is linked to checkpoint proteins

Pauleau, A.-L.; Bergner, A.; Kajtez, J.; Erhardt, S.

10.1101/394981 — cell biology — Posted on 2019-03-13

1990 Vertical and horizontal integration of multi-omics data with miodin

Ulfenborg, B.

10.1101/431429 — bioinformatics — Posted on 2019-03-13

1991 Identification and Ranking of Recurrent Neo-Epitopes in Cancer

Blanc, E.; Holtgrewe, M.; Dhamodaran, A.; Messerschmidt, C.; Willimsky, G.; Blankenstein, T.; Beule, D.

10.1101/389437 — genomics — Posted on 2019-03-13

1992 Integrating single-cell RNA-Seq with spatial transcriptomics in pancreatic ductal adenocarcinoma using multimodal intersection analysis

Moncada, R.; Wagner, F.; Chiodin, M.; Devlin, J. C.; Baron, M.; Hajdu, C. H.; Simeone, D.; Yanai, I.

10.1101/254375 — cancer biology — Posted on 2019-03-13

1993 Superresolved microparticle traction force microscopy reveals subcellular force patterns in immune cell-target interactions

Vorselen, D.; Wang, Y.; de Jesus, M. M.; Shah, P. K.; Footer, M. J.; Huse, M.; Cai, W.; Theriot, J. A.

10.1101/431221 — biophysics — Posted on 2019-03-13

1994 Genetic diversity of clinical Bordetella pertussis ST2 strains in comparison with vaccine reference strains of India

Sharma, N. C.; Anandan, S.; Devanga Ragupathi, N. K.; Muthuirulandi Sethuvel, D. P.; Vasudevan, K.; Kumar, D.; Gupta, S. K.; Sangal, L.; Murugesan, V.; Veeraraghavan, B.

10.1101/573543 — microbiology — Posted on 2019-03-13

1995 A systematic evaluation of the design, orientation, and sequence context dependencies of massively parallel reporter assays

Klein, J. C.; Agarwal, V.; Inoue, F.; Keith, A.; Martin, B.; Kircher, M.; Ahituv, N.; Shendure, J.

10.1101/576405 — genomics — Posted on 2019-03-13

1996 Diversification of the type IV filament super-family into machines for adhesion, secretion, DNA transformation and motility

Denise, R.; Abby, S. S.; Rocha, E. P.

10.1101/576694 — evolutionary biology — Posted on 2019-03-13

1997 Dual RNA-Seq meta-analysis in Plasmodium infection

Mukherjee, P.; Heitlinger, E.

10.1101/576116 — bioinformatics — Posted on 2019-03-13

1998 In silico learning of tumor evolution through mutational time series

Auslander, N.; Wolf, Y. I.; Koonin, E. V.

10.1101/577171 — bioinformatics — Posted on 2019-03-13

1999 Encircling the regions of the pharmacogenomic landscape that determine drug response

Fernandez-Torras, A.; Duran-Frigola, M.; Aloy, P.

10.1101/383588 — bioinformatics — Posted on 2019-03-13

2000 Nbs1 Mediates Assembly and Activity of the Mre11 complex

Kim, J. H.; Penson, A. V.; Taylor, B. S.; Petrini, J.

10.1101/576082 — cancer biology — Posted on 2019-03-13

2001 Multi-task learning predicts drug combination synergy in cells and in the clinic

Gilvary, C. M.; Dry, J. R.; Elemento, O.

10.1101/576017 — cancer biology — Posted on 2019-03-13

2002 Onchocerciasis-associated epilepsy in the Democratic Republic of Congo: Clinical description and relationship with microfilarial density

Siewe Fodjo, J. N.; Mandro, M. N.; Mukendi, D.; Tepage, F.; Menon, S.; Nakato, S.; Francoise, N.; Abhafule, G.; Wonya'rossi, D.; Anyolito, A.; Lokonda, R.; Hotterbeekx, A.; Colebunders, R.

10.1101/577247 — neuroscience — Posted on 2019-03-13

2003 No Evidence for Communication in the Complete Locked-in State

Spueler, M.

10.1101/287631 — neuroscience — Posted on 2019-03-13

2004 In silico identification of novel peptides with antibacterial activity against multidrug resistant Staphylococcus aureus

Oyama, L. B.; Olleik, H.; Teixeira, A. C. N.; Guidini, M. M.; Pickup, J. A.; Cookson, A. R.; Vallin, H.; Wilkinson, T.; Bazzolli, D.; Richards, J.; Wootton, M.; Mikut, R.; Hilpert, K.; Maresca, M.; Perrier, J.; Hess, M.; Mantovani, H. C.; Fernandez-Fuentes, N.; Creevey, C. J.; Huws, S. A.

10.1101/577221 — microbiology — Posted on 2019-03-13

2005 Cell-length heterogeneity: a population-level solution to growth/virulence trade-offs in the plant pathogen Dickeya dadantii

Cui, Z.; Yang, C.-H.; Kharadi, R. R.; Yuan, X.; Sundin, G. W.; Triplett, L. R.; Wang, J.; Zeng, Q.

10.1101/577296 — microbiology — Posted on 2019-03-13

2006 Directed migration shapes cooperation in spatial ecological public goods games

Funk, F. A.; Hauert, C.

10.1101/577205 — evolutionary biology — Posted on 2019-03-13

2007 Strategies based on sum of peak intensities may better reflect protein expression than peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform

Burat, B.; Gonzalez, J.; Sauvage, F.-L.; Aouad, H.; Arnion, H.; Pinault, E.; Marquet, P.; Essig, M.

10.1101/577254 — cell biology — Posted on 2019-03-13

2008 SPHIRE-crYOLO: A fast and accurate fully automated particle picker for cryo-EM

Wagner, T.; Merino, F.; Stabrin, M.; Moriya, T.; Antoni, C.; Apelbaum, A.; Hagel, P.; Sitsel, O.; Raisch, T.; Prumbaum, D.; Quentin, D.; Roderer, D.; Tacke, S.; Siebolds, B.; Schubert, E.; Shaikh, T. R.; Lill, P.; Gatsogiannis, C.; Raunser, S.

10.1101/356584 — biophysics — Posted on 2019-03-13

2009 The association between dietary habits and periodontal disease in young adult women

Hosoda, A.; Komagamine, Y.; Kanazawa, M.; Hama, Y.; Kojo, A.; Minakuchi, S.

10.1101/577155 — pathology — Posted on 2019-03-13

2010 Human recombinant erythropoietin improves motor function in rats with spinal cord compression myelopathy

Tanaka, T.; Murata, H.; Miyazaki, R.; Yoshizumi, T.; Sato, M.; Ohtake, M.; Tateishi, K.; Kim, P.; Yamamoto, T.

10.1101/577130 — neuroscience — Posted on 2019-03-13

2011 Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti

Danet, L.; Beauclair, G.; Berthet, M.; Moratorio, G.; Gracias, S.; Tangy, F.; Choumet, V.; jouvenet, n.

10.1101/577213 — microbiology — Posted on 2019-03-13

2012 Co-occurrence of organic and inorganic N sources influences asparagine uptake and internal amino acid profiles in white clover

Czaban, W.; Rasmussen, J.

10.1101/577114 — plant biology — Posted on 2019-03-13

2013 Effects of dietary taurine level on visual function in European sea bass (Dicentrarchus labrax)

Brill, R.; Horodysky, A.; Place, A.; Larkin, M.; Reimschuessel, R.

10.1101/577023 — physiology — Posted on 2019-03-13

2014 Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, P53, Caspase-3 and Bcl-2 in STZ-induced diabetic rats

Ahmed, O. M.; Ali, T. M.; Abdel Gaid, M. A.; Elberry, A.

10.1101/577106 — pharmacology and toxicology — Posted on 2019-03-13

2015 Towards a real-world brain-computer interface for image retrieval

McCartney, B.; Martinez-del-Rincon, J.; Devereux, B.; Murphy, B.

10.1101/576983 — neuroscience — Posted on 2019-03-13

2016 Timing seed germination under changing salinity: a key role of the ERECTA receptor-kinases

Nanda, A. K.; El Habti, A.; Hocart, C.; Masle, J.

10.1101/576512 — plant biology — Posted on 2019-03-13

2017 Uncovering mechanisms of global ocean change effects on the Dungeness crab (Cancer magister) through metabolomics analysis

Trigg, S. A.; McElhany, P.; Maher, M.; Perez, D.; Busch, D. S.; Nichols, K. M.

10.1101/574798 — systems biology — Posted on 2019-03-13

2018 What’s in Your Body of Water? Reducing the Psychological Distance of Pharmaceutical Pollution through Metaphoric Framing in Risk Communication (A Pilot Study)

Millarhouse, A. Z.; Vatovec, C.; Niles, M. T.; Ivakhiv, A.

10.1101/575639 — scientific communication and education — Posted on 2019-03-13

2019 Phylogenetic reclassification of vertebrate melatonin receptors to include Mel1d

Macqueen, D. J.; Ebbesson, L. O. E.; Hazlerigg, D. G.; Denker, E.

10.1101/574384 — physiology — Posted on 2019-03-13

2020 %svy_logistic_regression: A generic SAS(R) macro for simple and multiple logistic regression and creating quality publication-ready tables using survey or non-survey data

Muthusi, J.; Mwalili, S.; Young, P.

10.1101/575605 — bioinformatics — Posted on 2019-03-13

2021 Context-specific effects of facial dominance and trustworthiness on hypothetical leadership decisions

Ferguson, H. S.; Owen, A.; Hahn, A.; Torrance, J.; DeBruine, L. M.; Jones, B. C.

10.1101/575597 — animal behavior and cognition — Posted on 2019-03-13

2022 Doberman pinschers present autoimmunity associated with functional autoantibodies: a model to study the autoimmune background of human dilated cardiomyopathy

Schimke, I.; Wess, G.; Wallukat, G.; Fritscher, A.; Becker, N.-P.; Wenzel, K.; Müller, J.

10.1101/575613 — pathology — Posted on 2019-03-13

2023 Empirical examination of the replicability of associations between brain structure and psychological variables

Kharabian, S.; Eickhoff, S.; Hoffstaedter, F.; Genon, S.

10.1101/496729 — neuroscience — Posted on 2019-03-13

2024 Morphofunctional deficits in the cerebral cortex of NeuroD2 mutant mice are associated with autism/schizophrenia-like behaviors

Bugeon, S.; Lafi, S.; Beurrier, C.; Sahu, S.; Runge, K.; Schaller, F.; Loubat, A.; Mathieu, R.; Herault, L.; Gaillard, S.; Cahuc, M.; Pallesi-Pocachard, E.; Montheil, A.; Bosio, A.; Represa, A.; Cardoso, C.; Cremer, H.; de Chevigny, A.

10.1101/296889 — neuroscience — Posted on 2019-03-13

2025 Prevalence of parasitic infections among recent immigrants to Chicago

Herrick, J. A.; Nordstrom, M.; Maloney, P.; Rodriguez, M.; Naceanceno, K.; Enamorado, G. G.; Mejia, R.; Hershow, R.

10.1101/575779 — epidemiology — Posted on 2019-03-13

2026 Hierarchical temporal prediction captures motion processing from retina to higher visual cortex

Singer, Y.; Willmore, B. D.; King, A. J.; Harper, N. S.

10.1101/575464 — neuroscience — Posted on 2019-03-13

2027 Looking for a reference for large datasets: relative reliability of visual and automatic sleep scoring

Berthomier, C.; Muto, V.; Schmidt, C.; Vandewalle, G.; Jaspar, M.; Devillers, J.; Gaggioni, G.; Chellappa, S.; Meyer, C.; Phillips, C.; Salmon, E.; Berthomier, P.; Prado, J.; Benoit, O.; Brandewinder, M.; Mattout, J.; Maquet, P.

10.1101/576090 — neuroscience — Posted on 2019-03-13

2028 Effect of Interpopulation Spike-Timing-Dependent Plasticity on Synchronized Rhythms in Neuronal Networks with Inhibitory and Excitatory Populations

Kim, S.-Y.; Lim, W.

10.1101/576314 — neuroscience — Posted on 2019-03-13

2029 Rapid recalibration of temporal order judgements: Response bias accounts for contradictory results

Keane, B.; Bland, N. S.; Matthews, N.; Carroll, T. J.; Wallis, G.

10.1101/576249 — neuroscience — Posted on 2019-03-13

2030 The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast

Serbyn, N.; Noireterre, A.; Bagdiul, I.; Plank, M.; Michel, A. H.; Loewith, R.; Kornmann, B.; Stutz, F.

10.1101/575860 — molecular biology — Posted on 2019-03-13

2031 Biotic interactions affect fitness across latitudes, but only drive local adaptation in the tropics

Hargreaves, A.; Germain, R.; Bontrager, M.; Persi, J.; Angert, A.

10.1101/575498 — evolutionary biology — Posted on 2019-03-13

2032 Frequent birth of de novo genes in the compact yeast genome

Blevins, W. R.; Ruiz-Orera, J.; Messeguer, X.; Blasco-Moreno, B.; Villanueva-Canas, J. L.; Espinar, L.; Diez, J.; Carey, L.; Alba, M. M.

10.1101/575837 — evolutionary biology — Posted on 2019-03-13

2033 Best practices for making reliable inferences from citizen science data: case study using eBird to estimate species distributions

Johnston, A.; Hochachka, W. M.; Strimas-Mackey, M.; Ruiz Gutierrez, V.; Robinson, O. J.; Miller, E. T.; Auer, T.; Kelling, S. T.; Fink, D.

10.1101/574392 — ecology — Posted on 2019-03-13

2034 CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

Erdmann, S.; Niederstadt, L.; Koziolek, E. J.; Castillo Gomez, J. D.; Prasad, S.; Wagener, A.; von Hacht, J. L.; Hallmann, S.; Exner, S.; Bandholtz, S.; Beindorff, N.; Brenner, W.; Groetzinger, C.

10.1101/575902 — cancer biology — Posted on 2019-03-13

2035 Germline genetic determination of cancer progression and survival

Ostendorf, B. N.; Tafreshian, K. N.; Adaku, N.; Bilanovic, J.; Tavora, B.; Tavazoie, S. F.

10.1101/576181 — cancer biology — Posted on 2019-03-13

2036 Neural measures of subsequent memory reflect endogenous variability in cognitive function

Weidemann, C. T.; Kahana, M.

10.1101/576173 — neuroscience — Posted on 2019-03-13

2037 Send-receive communication asymmetry in brain networks: Inferring directionality of neural signalling from undirected structural connectomes

Seguin, C.; Razi, A.; Zalesky, A.

10.1101/573071 — neuroscience — Posted on 2019-03-13

2038 The microbiota regulates inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination

McMurran, C.; Guzman de la Fuente, A.; Penalva, R.; Menachem-Zidon, O.; Dombrowski, Y.; Gonzalez, G.; Zhao, C.; Krause, F.; Young, A.; Griffin, J.; Jones, C.; Hollins, C.; Heimesaat, M.; Fitzgerald, D.; Franklin, R.

10.1101/575829 — neuroscience — Posted on 2019-03-13

2039 Supra-threshold perception and neural representation of tones presented in noise in conditions of masking release

Egger, K.; Dau, T.; Epp, B.

10.1101/575720 — neuroscience — Posted on 2019-03-13

2040 Sequencing Complete Genomes of RNA Viruses With MinION Nanopore: Finding Associations Between Mutations

Harel, N.; Meir, M.; Gophna, U.; Stern, A.

10.1101/575480 — genetics — Posted on 2019-03-13

2041 Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications

liau, y.; Maggo, S.; Miller, A. L.; Pearson, J. F.; Kennedy, M. A.; Cree, S. L.

10.1101/576280 — genetics — Posted on 2019-03-13

2042 Dynamic and synergistic influences of air temperature and rainfall on general flowering in a Bornean lowland tropical forest

Ushio, M.; Osada, Y.; Kumagai, T.; Kume, T.; Sylvester Pungga, R.; Nakashizuka, T.; Itioka, T.; Sakai, S.

10.1101/576231 — ecology — Posted on 2019-03-13

2043 Ligand-independent role of ErbB3 in endocytotic recycling

Saez-Ibanez, A. R.; Scheffler, J. M.; Terabayashi, T.; Idevall, O.; Ferby, I.

10.1101/575449 — cell biology — Posted on 2019-03-13

2044 Rosa26 docking sites for investigating genetic circuit silencing in stem cells

Fitzgerald, M.; Gibbs, C.; Deans, T.

10.1101/575266 — cell biology — Posted on 2019-03-13

2045 Characterization and repurposing of the endogenous Type I-F CRISPR-Cas system of Zymomonas mobilis for genome engineering

Zheng, Y.; Han, J.; Liang, W.; Li, R.; Hu, X.; Wang, B.; Shen, W.; Ma, X.; Ma, L.; Yi, L.; Yang, S.; Peng, W.

10.1101/576355 — bioengineering — Posted on 2019-03-13

2046 Identification of master regulators in goblet cells and Paneth cells using transcriptomics profiling of gut organoids and multi-layered networks

Treveil, A.; Sudhakar, P.; Matthews, Z. J.; Wrzesinski, T.; Jones, E. J.; Olbei, M.; Hautefort, I.; Hall, L. J.; Carding, S. R.; Mayer, U.; Powell, P. P.; Wileman, T.; Di Palma, F.; Haerty, W.; Korcsmaros, T.

10.1101/575845 — systems biology — Posted on 2019-03-13

2047 Coordinated development of the mouse extrahepatic bile duct: implications for neonatal susceptibility to biliary injury

Khandekar, G.; Llewellyn, J.; Kriegermeier, A.; Waisbourd-Zinman, O.; Johnson, N.; Du, Y.; Giwa, R.; Liu, X.; Kisseleva, T.; Russo, P. A.; Theise, N. D.; Wells, R. G.

10.1101/576256 — physiology — Posted on 2019-03-13

2048 Pore-modulating toxins exploit inherent slow inactivation to block K+ channels

Karbat, I.; Altman-Gueta, H.; Fine, S.; Szanto, T.; Hamer-Rogotner, S.; Dym, O.; Frolow, F.; Gordon, D.; Panyi, G.; Gurevitz, M.; Reuveny, E.

10.1101/576132 — pharmacology and toxicology — Posted on 2019-03-13

2049 Acetylcholine release inhibits distinct excitatory inputs onto hippocampal CA1 pyramidal neurons via different cellular and network mechanisms

Goswamee, P.; McQuiston, R.

10.1101/575811 — neuroscience — Posted on 2019-03-13

2050 Single and population coding of taste in the gustatory cortex of awake mice

Levitan, D.; Lin, J.-Y.; Wachutka, J.; Mukherjee, N.; Nelson, S. B.; Katz, D. B.

10.1101/575522 — neuroscience — Posted on 2019-03-13

2051 A validated workflow for rapid taxonomic assignment and monitoring of a national fauna of bees (Apiformes) using high throughput barcoding

Creedy, T. J.; Norman, H.; Tang, C. Q.; Chin, K. Q.; Andujar, C.; Arribas, P.; O'Connor, R.; Carvell, C.; Notton, D. G.; Vogler, A. P.

10.1101/575308 — molecular biology — Posted on 2019-03-13

2052 Dual activity of PNGM-1, a metallo-β-lactamase and tRNase Z, pinpoints the evolutionary origin of subclass B3 metallo-β-lactamases

Lee, J. H.; Takahashi, M.; Jeon, J. H.; Kang, L.-W.; Seki, M.; Park, K. S.; Hong, M.-K.; Park, Y. S.; Kim, T. Y.; Karim, A. M.; Lee, J.-H.; Nashimoto, M.; Lee, S. H.

10.1101/575373 — microbiology — Posted on 2019-03-13

2053 Minimally-invasive nasal sampling in children offers accurate pneumococcal colonization detection

Nikolaou, E.; Blizard, A.; Pojar, S.; Mitsi, E.; German, E. L.; Reine, J.; Hill, H.; McNamara, P. S.; Collins, A. M.; Ferreira, D. M.; Jochems, S. P.

10.1101/573196 — microbiology — Posted on 2019-03-13

2054 The quail as an avian model system: its genome provides insights into social behaviour, seasonal biology and infectious disease response

Morris, K.; Hindle, M. M.; Boitard, S.; Burt, D. W.; Danner, A. F.; Eory, L.; Forrest, H. L.; Gourichon, D.; Gros, J.; Hillier, L.; Jaffredo, T.; Khoury, H.; Lansford, R.; Leterrier, C.; Loudon, A.; Mason, A. S.; Meddle, S. L.; Minvielle, F.; Minx, P.; Pitel, F.; Seiler, J. P.; Shimmura, T.; Tomlinson, C.; Vignal, A.; Webster, R. G.; Yoshimura, T.; Warren, W. C.; Smith, J.

10.1101/575332 — genomics — Posted on 2019-03-13

2055 Optimisation of rapid STR analysis using a standard DNA forensic pipeline

Gammon, K. S.; Mayers, C. N.

10.1101/575357 — genetics — Posted on 2019-03-13

2056 Single-base mapping of m6A by an antibody-independent method

Zhang, Z.; Chen, L.-Q.; Zhao, Y.-L.; Yang, C.-G.; Roundtree, I. A.; Zhang, Z.; Ren, J.; Xie, W.; He, C.; Luo, G.-Z.

10.1101/575555 — genetics — Posted on 2019-03-13

2057 A Bayesian Approach for Inferring the Impact of a Discrete Character on Rates of Continuous-Character Evolution in the Presence of Background Rate Variation

May, M. R.; Moore, B. R.

10.1101/576207 — evolutionary biology — Posted on 2019-03-13

2058 Contrasting population genetic structure in Acropora coral hosts and their algal symbionts across multiple spatial scales

Davies, S. W.; Wham, D.; Kanke, M.; Matz, M.

10.1101/575183 — ecology — Posted on 2019-03-13

2059 PINK1-parkin-mediated mitophagy generates stereotyped somatic mosaicism of the mitochondrial genome

Ahier, A.; Dai, C.-Y.; Zuryn, S.

10.1101/576165 — cell biology — Posted on 2019-03-13

2060 LTK is an ER-resident receptor tyrosine kinase that regulates secretion

Centonze, F. G.; Reiterer, V.; Nalbach, K.; Saito, K.; Pawlowski, K.; Behrends, C.; Farhan, H.

10.1101/575365 — cell biology — Posted on 2019-03-13

2061 Bone morphogenetic protein 4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone

Westhrin, M.; Holien, T.; Zahoor, M.; Moen, S. H.; Buene, G.; Stordal, B.; Hella, H.; Yuan, H.; de Bruijn, J. D.; Martens, A.; Groen, R. W.; Bosch, F.; Smith, U.; Sponaas, A. M.; Sundan, A.; Standal, T.

10.1101/575159 — cancer biology — Posted on 2019-03-13

2062 Glioblastomas derived from genetically modified pluripotent stem cells recapitulate pathobiology

Koga, T.; Benitez, J. A.; Chaim, I. A.; Markmiller, S.; Parisian, A. D.; Turner, K. M.; Hessenauer, F. M.; D'Antonio, M.; Nguyen, N.-p. D.; Saberi, S.; Ma, J.; Miki, S.; Boyer, A. D.; Ravits, J.; Frazer, K. A.; Bafna, V.; Chen, C. C.; Mischel, P. S.; Yeo, G. W.; Furnari, F. B.

10.1101/576009 — cancer biology — Posted on 2019-03-13

2063 A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic aberration based molecular signatures

Diossy, M.; Sztupinszki, Z.; Borcsok, J.; Krzystanek, M.; Tisza, V.; Spisak, S.; Rusz, O.; Csabai, I.; Moldvay, J.; Pedersen, A. G.; Szuts, D.; Szallasi, Z.

10.1101/576223 — cancer biology — Posted on 2019-03-13

2064 The roles of microtubules and membrane tension in axonal beading, retraction, and atrophy

Datar, A.; Ameeramja, J.; Bhat, A.; Srivastava, R.; Bernal, R.; Prost, J.; Callan-Jones, A.; Pullarkat, P. A.

10.1101/575258 — biophysics — Posted on 2019-03-13

2065 MALVA: genotyping by Mapping-free ALlele detection of known VAriants

Bernardini, G.; Bonizzoni, P.; Denti, L.; Previtali, M.; Schönhuth, A.

10.1101/575126 — bioinformatics — Posted on 2019-03-13

2066 CytoGPS: A Web-Enabled Karyotype Analysis Tool for Cytogenetics

Abrams, Z. B.; Zhang, L.; Abruzzo, L. V.; Heerema, N. A.; Li, S.; Dillon, T.; Rodriguez, R.; Coombes, K.; Payne, P. R. O.

10.1101/575423 — bioinformatics — Posted on 2019-03-13

2067 Rapid RNA sequencing data analysis using serverless computing

Hung, L.-H.; Kumanov, D.; Niu, X.; Lloyd, W.; Yeung, K. Y.

10.1101/576199 — bioinformatics — Posted on 2019-03-13

2068 Decentralized Distribution-sampled Classification Models with Application to Brain Imaging

Lewis, N.; Gazula, H.; Plis, S.; calhoun, v.

10.1101/576108 — bioinformatics — Posted on 2019-03-13

2069 Engineered phenotype patterns in microbial populations

Bittihn, P.; Didovyk, A.; Tsimring, L. S.; Hasty, J.

10.1101/575068 — synthetic biology — Posted on 2019-03-13

2070 Chrysin, but not the flavone backbone, decreases anxiety-like behavior in animal tests

Ponciano, L. J.; Costa, B. P.; Feitosa, L. M.; Campos, K. S.; Chaves, S. N.; Cueto-Escobedo, J.; Lima-Maximino, M. G.; Rodriguez-Landa, J. F.; Maximino, C.

10.1101/575514 — pharmacology and toxicology — Posted on 2019-03-13

2071 A genetically adaptable strategy for ribose scavenging in a human gut symbiont plays a diet-dependent role in colon colonization

Glowacki, R.; Pudlo, N.; Tuncil, Y.; Luis, A.; Terekhov, A.; Hamaker, B.; Martens, E.

10.1101/574913 — microbiology — Posted on 2019-03-13

2072 The enemy from within: a prophage of Roseburia intestinalis systematically turns lytic in the mouse gut, driving bacterial adaptation by CRISPR spacer acquisition

Cornuault, J. K.; Moncaut, E.; Loux, V.; Mathieu, A.; Sokol, H.; Petit, M.-A.; De Paepe, M.

10.1101/575076 — microbiology — Posted on 2019-03-13

2073 Non-lethal oxidative stress boosts bacterial survival and evolvability under lethal exposure

Rodriguez Rojas, A.; Kim, J.; Johnston, P. R.; Makarova, O.; Eravci, M.; Weise, C.; Hengge, R.; Rolff, J.

10.1101/575134 — evolutionary biology — Posted on 2019-03-13

2074 Multi-enhancer transcriptional hubs confer phenotypic robustness

Tsai, A.; Alves, M.; Crocker, J.

10.1101/575175 — developmental biology — Posted on 2019-03-13

2075 Maximum Likelihood Reconstruction of Ancestral Networks by Integer Linear Programming

Rajan, V.; Kingsford, C.; Zhang, X.

10.1101/574814 — bioinformatics — Posted on 2019-03-13

2076 TrackUSF, a novel methodology for automated analysis of ultrasonic vocalizations, reveals modified social communication in a rat model of autism

Netser, S.; Nahardiya, G.; Weiss-Dicker, G.; Dadush, R.; Goussha, Y.; Harony-Nicolas, H.; Cohen, L.; Crammer, K.; Wagner, S.

10.1101/575191 — animal behavior and cognition — Posted on 2019-03-13

2077 Machine learning Classification of Dyslexic Children based on EEG Local Network Features

Rezvani, Z.; Zare, M.; Zaric, G.; Bonte, M.; Tijms, J.; Van der Molen, M. W.; Fraga Gonzalez, G.

10.1101/569996 — neuroscience — Posted on 2019-03-13

2078 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth

Galdi, P.; Blesa, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P.

10.1101/569319 — neuroscience — Posted on 2019-03-12

2079 The cellular response towards lanthanum is substrate specific and reveals a novel route for glycerol metabolism in Pseudomonas putida KT2440

Wehrmann, M.; Toussaint, M.; Pfannstiel, J.; Billard, P.; Klebensberger, J.

10.1101/567529 — microbiology — Posted on 2019-03-12

2080 The bacterial endosymbiont Wolbachia increases reproductive investment and accelerates the life cycle of ant colonies

SINGH, R.; Linksvayer, T. A.

10.1101/574921 — evolutionary biology — Posted on 2019-03-12

2081 The fitness cost and benefit of phase separated protein deposits

Sanchez de Groot, N.; Torrent Burgas, M.; Ravarani, C. N. J.; Trusina, A.; Ventura, S.; Babu, M.

10.1101/574657 — systems biology — Posted on 2019-03-12

2082 Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility

Lautz, J. D.; Gniffke, E. P.; Brown, E. A.; Immendorf, K. B.; Mendel, R. D.; Smith, S. E. P.

10.1101/576074 — neuroscience — Posted on 2019-03-12

2083 Visual recognition of the female body axis drives spatial elements of male courtship in Drosophila melanogaster

McKinney, R.; Ben-Shahar, Y.

10.1101/576322 — neuroscience — Posted on 2019-03-12

2084 Cascaded-CNN: Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps

Moritz, S.; Pfab, J.; Wu, T.; Hou, J.; Cheng, J.; Cao, R.; Wang, L.; Si, D.

10.1101/572990 — molecular biology — Posted on 2019-03-12

2085 Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology

Mesman, A. W.; Soto, M.; Coit, J.; Calderon, R.; Aliaga, J.; Pollock, N. R.; Mendoza, M.; Mestanza, F. M.; Mendoza, C. J.; Murray, M. B.; Lecca, L.; Holmberg, R.; Franke, M. F.

10.1101/564088 — microbiology — Posted on 2019-03-12

2086 Single cell expression variability in highly homogeneous populations of human cells is widespread, heritable, and implies cell function

Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J.

10.1101/574426 — genetics — Posted on 2019-03-12

2087 Cultured pluripotent planarian stem cells retain potency and express proteins from exogenously introduced mRNAs

Lei, K.; McKinney, S. A.; Ross, E. J.; Lee, H.-C.; Sanchez Alvarado, A.

10.1101/573725 — cell biology — Posted on 2019-03-12

2088 The life of P.I. - Transitions to Independence in Academia

Acton, S. E.; Bell, A.; Toseland, C. P.; Twelvetrees, A.

10.1101/571935 — scientific communication and education — Posted on 2019-03-12

2089 M1 disruption delays motor processes but not deliberation about action choices

Derosiere, G.; Thura, D.; Cisek, P.; Duque, J.

10.1101/501205 — neuroscience — Posted on 2019-03-12

2090 CHIME: CMOS-hosted in-vivo microelectrodes for massively scalable neuronal recordings

Kollo, M.; Racz, R. R.; Hanna, M.--E. S.; Obaid, A. M.; Angle, M. R.; Wray, W.; Kong, Y.; Hierlemann, A.; Muller, J.; Melosh, N. A.; Schaefer, A. T.

10.1101/570069 — neuroscience — Posted on 2019-03-12

2091 Learning-accelerated Discovery of Immune-Tumour Interactions

Ozik, J.; Collier, N.; Heiland, R.; Macklin, P.

10.1101/573972 — systems biology — Posted on 2019-03-12

2092 Automated and Manual Quantification of Tumour Cellularity in Digital Slides for Tumour Burden Assessment

Akbar, S.; Peikari, M.; Salama, S.; Panah, A. Y.; Nofech-Momes, S.; Martel, A. L.

10.1101/571190 — pathology — Posted on 2019-03-12

2093 Insights into an alternative pathway for glycerol metabolism in a glycerol kinase deficient Pseudomonas putida KT2440

Walsh, M.; Casey, W.; Kenny, S. T.; Narancic, T.; Blank, L. M.; Wierckx, N.; Ballerstedt, H.; O Connor, K. E.

10.1101/567230 — microbiology — Posted on 2019-03-12

2094 Assessing graph-based read mappers against a novel baseline approach highlights strengths and weaknesses of the current generation of methods

Grytten, I.; Rand, K. D.; Nederbragt, A. J.; Sandve, G. K.

10.1101/538066 — bioinformatics — Posted on 2019-03-12

2095 Vigour/tolerance trade-off in cultivated sunflower (Helianthus annuus) response to salinity stress is linked to leaf elemental composition

Temme, A.; Kerr, K. L.; Donovan, L. A.

10.1101/447128 — plant biology — Posted on 2019-03-12

2096 A comparison of two mathematical models of the cerebrospinal fluid dynamics

Donatelli, D.; Marcati, P.; Romagnoli, L.

10.1101/573337 — neuroscience — Posted on 2019-03-12

2097 Differential Tractography as a Track-Based Biomarker for Neurodegeneration

Yeh, F.-C.; Zaydan, I. M.; Suski, V. R.; Lacomis, D.; Richardson, R. M.; Maroon, J.; Barrios-Martinez, J.

10.1101/576025 — neuroscience — Posted on 2019-03-12

2098 Intrinsic Cell-type Selectivity and Inter-neuronal Connectivity Alteration by Transcranial Focused Ultrasound

Yu, K.; Niu, X.; Krook-Magnuson, E.; He, B.

10.1101/576066 — neuroscience — Posted on 2019-03-12

2099 Non-linear effects of socioeconomic status on brain development: associations between parental occupation, cortical thickness and language skills in childhood and adolescence

Khundrakpam, B.; Choudhury, S.; Vainik, U.; Al-Sharif, N.; Bhutani, N.; Evans, A.; Pediatric Imaging, Neurocognition and Genetics Stu,

10.1101/575993 — neuroscience — Posted on 2019-03-12

2100 Estimating relatedness between malaria parasites

Taylor, A. R.; Jacob, P. E.; Neafsey, D. E.; Buckee, C. O.

10.1101/575985 — genetics — Posted on 2019-03-12

2101 The gene annotated by the locus tag At3g08860 encodes a β-alanine/L-alanine aminotransferase in Arabidopsis thaliana

Parthasarathy, A.; Savka, F. C.; Hudson, A. O.

10.1101/576041 — plant biology — Posted on 2019-03-12

2102 Refinement of the primate corticospinal pathway during prenatal development

Ribeiro Gomes, A. R.; Olivier, E.; Killackey, H. P.; Giroud, P.; Berland, M.; Knoblauch, K.; Dehay, C.; Kennedy, H.

10.1101/575936 — neuroscience — Posted on 2019-03-12

2103 Watered-down biodiversity? A comparison of metabarcoding results from DNA extracted from matched water and bulk tissue biomonitoring samples

Hajibabaei, M.; Porter, T.; Robinson, C.; Baird, D.; Shokralla, S.; Wright, M.

10.1101/575928 — ecology — Posted on 2019-03-12

2104 Population dynamics and age-dependent mortality processes in tropical reptiles

Cayuela, H.; Akani, G. C.; Hema, E. M.; Eniang, E. A.; Amadi, N.; Ajong, S. N.; Dendi, D.; Petrozzi, F.; Luiselli, L.

10.1101/575977 — ecology — Posted on 2019-03-12

2105 Btbd6-dependent Plzf recruitment to Cul3 E3 ligase complexes through BTB domain heterodimerization

Ismail, M. S.; Martin, S. R.; Ball, N. J.; Taylor, I. A.; Howell, S.; Wilkinson, D. G.; Smerdon, S. J.

10.1101/575910 — biochemistry — Posted on 2019-03-12

2106 SurfaceGenie: A web-based application for integrating predictive and experimental data for rational candidate surface marker prioritization

Waas, M.; Terai Snarrenberg, S.; Littrell, J.; Jones Lipinski, R.; Hansen, P.; Corbett, J.; Gundry, R.

10.1101/575969 — systems biology — Posted on 2019-03-12

2107 ARMOR: an Automated Reproducible MOdular workflow for preprocessing and differential analysis of RNA-seq data

Orjuela, S.; Huang, R.; Hembach, K.; Robinson, M.; Soneson, C.

10.1101/575951 — bioinformatics — Posted on 2019-03-12

2108 Inter-ecosystem variation in the food-collection behaviour in climbing perch Anabas testudineus, a freshwater fish

VV, B.; V B, R.; Sinha, A.

10.1101/573600 — animal behavior and cognition — Posted on 2019-03-12

2109 The symmetrical pattern of base-pair substitution rates across the chromosome in Escherichia coli has multiple causes

Niccum, B. A.; Lee, H.; MohammedIsmail, W.; Tang, H.; Foster, P. L.

10.1101/523696 — microbiology — Posted on 2019-03-12

2110 The genetic architecture of sporadic and recurrent miscarriage

Laisk, T.; Soares, A. L. G.; Ferreira, T.; Painter, J. N.; Laber, S.; Bacelis, J.; Chen, C.-Y.; Lepamets, M.; Lin, K.; Liu, S.; Millwood, I. Y.; Ramu, A.; Southcombe, J.; Andersen, M. S.; Yang, L.; Becker, C. M.; Gordon, S. D.; Byberg-Grauholm, J.; Helgeland, O.; Hougaard, D. M.; Jin, X.; Johansson, S.; Juodakis, J.; Kartsonaki, C.; Kukushkina, V.; Lind, P. A.; Metspalu, A.; Montgomery, G. W.; Morris, A. P.; Mortensen, P. B.; Njolstad, P. R.; Nyholt, D. R.; Lippincott, M.; Seminara, S.; Salumets, A.; Snieder, H.; Zondervan, K.; Chen, Z.; Conrad, D. F.; Jacobsson, B.; Li, L.; Martin, N. G.; Nea

10.1101/575167 — genetics — Posted on 2019-03-12

2111 Chronic aromatase inhibition increases ventral hippocampal neurogenesis in middle-aged female mice

Chaiton, J.; Wong, S.; Galea, L.

10.1101/434662 — neuroscience — Posted on 2019-03-12

2112 Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming

Wang, H.; Sheehan, R. P.; Palmer, A. C.; Everley, R. A.; Boswell, S. A.; Ron-Harel, N.; Ringel, A. E.; Holton, K. M.; Jacobson, C. A.; Erickson, A. R.; Maliszewski, L.; Haigis, M. C.; Sorger, P. K.

10.1101/365841 — pharmacology and toxicology — Posted on 2019-03-12

2113 Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes

Yamasaki, R.; Song, S.; Benedik, M.; Wood, T. K.

10.1101/486985 — microbiology — Posted on 2019-03-12

2114 Network organization of antibody interactions in sequence and structure space: the RADARS model

Prechl, J.

10.1101/438804 — systems biology — Posted on 2019-03-12

2115 Frontal and parietal alpha oscillations reflect attentional modulation of cross-modal matching

Misselhorn, J.; Friese, U.; Engel, A. K.

10.1101/477034 — neuroscience — Posted on 2019-03-12

2116 Virtual ChIP-seq: Predicting transcription factor binding by learning from the transcriptome

Karimzadeh, M.; Hoffman, M. M.

10.1101/168419 — bioinformatics — Posted on 2019-03-12

2117 Connectivity profile of thalamic deep brain stimulation to effectively treat essential tremor

Al-Fatly, B.; Ewert, S.; Kuebler, D.; Kroneberg, D.; Horn, A.; Kuehn, A. A.

10.1101/575209 — neuroscience — Posted on 2019-03-12

2118 A multi-state model of the CaMKII dodecamer suggests a role for calmodulin in maintenance of autophosphorylation

Pharris, M. C.; Bartol, T. M.; Sejnowski, T. J.; Kennedy, M. B.; Stefan, M. I.; Kinzer-Ursem, T. L.

10.1101/575712 — neuroscience — Posted on 2019-03-12

2119 NGF-mediated photoablation of nociceptors reduces pain behavior in mice

Nocchi, L.; Portulano, C.; Franciosa, F.; Doleschall, B.; Panea, M.; Roy, N.; Maffei, M.; Gargano, A.; Perlas, E.; Heppenstall, P.

10.1101/575274 — neuroscience — Posted on 2019-03-12

2120 A consensus set of genetic vulnerabilities to ATR inhibition

Hustedt, N.; Alvarez-Quilon, A.; McEwan, A.; Yuan, J. Y.; Cho, T.; Koob, L.; Hart, T.; Durocher, D.

10.1101/574533 — molecular biology — Posted on 2019-03-12

2121 The gut microbiota regulates mouse biliary regenerative responses

Liu, W.; Yan, C.; Zhang, B.; Chen, R.; Yu, Q.; Li, X.; Zhang, Y.; Hua, H.; Wei, Y.; Kou, Y.; Liu, Z.; Tang, R.; Zheng, K.; Wang, Y.

10.1101/575050 — microbiology — Posted on 2019-03-12

2122 Combining genetic crosses and pool targeted DNA-seq for untangling genomic variations associated with resistance to multiple insecticides in the dengue vector Aedes aegypti

Cattel, J.; Faucon, F.; Leperon, B.; Sherpa, S.; Monchal, M.; Grillet, L.; Gaude, T.; Laporte, F.; Dusfour, I.; Reynaud, s.; David, J.-P.

10.1101/575753 — genomics — Posted on 2019-03-12

2123 Reproductive success of Eastern Bluebirds (Sialia sialis) varies with the timing and severity of drought

Carleton, R. E.; Graham, J. H.; Lee, A.; Taylor, Z. P.; Carleton, J. F.

10.1101/575647 — ecology — Posted on 2019-03-12

2124 Deep Learning on Chaos Game Representation for Proteins

Loechel, H. F.; Eger, D.; Sperlea, T.; Heider, D.

10.1101/575324 — bioinformatics — Posted on 2019-03-12

2125 Viral host prediction with Deep Learning

Mock, F.; Viehweger, A.; Barth, E.; Marz, M.

10.1101/575571 — bioinformatics — Posted on 2019-03-12

2126 Lumen expansion facilitates epiblast-primitive endoderm fate specification in the mouse blastocyst formation.

Ryan, A. Q.; Chan, C. J.; Graner, F.; Hiiragi, T.

10.1101/575282 — developmental biology — Posted on 2019-03-12

2127 A Probabilistic Programming Approach to Protein Structure Superposition

Sanz Moreta, L.; Al-Sibahi, A. S. S.; Hamelryck, T.; Theobald, D.; Rommes, B. N.; Bullock, W.; Manoukian, A.

10.1101/575431 — bioinformatics — Posted on 2019-03-12

2128 Bcl-xL dynamics and cancer-associated mutations under the lens of protein structure networks and biomolecular simulations

Sora, V.; Papaleo, E.

10.1101/574699 — bioinformatics — Posted on 2019-03-12

2129 COALIA: a computational model of human EEG for consciousness research

Bensaid, S.; Modolo, J.; Merlet, I.; Wendling, F.; Benquet, P.

10.1101/575043 — neuroscience — Posted on 2019-03-12

2130 Flow arrest in the plasma membrane

Chein, M.; Perlson, E.; Roichman, Y.

10.1101/575456 — biophysics — Posted on 2019-03-12

2131 Chestnut extract but not sodium salicylate decrease the severity of diarrhea and enterotoxigenic Escherichia coli F4 shedding in artificially infected piglets

Girard, M.; Hu, D.; Pradervand, N.; Neuenschwander, S.; Bee, G.

10.1101/575662 — physiology — Posted on 2019-03-12

2132 Effects of persistent sodium current blockade in respiratory circuits depend on the pharmacological mechanism of action and network dynamics

Phillips, R. S.; Rubin, J. E.

10.1101/575688 — neuroscience — Posted on 2019-03-12

2133 There is no single functional atlas even for a single individual: Parcellation of the human brain is state dependent

Salehi, M.; Greene, A. S.; Karbasi, A.; Shen, X.; Scheinost, D.; Constable, R. T.

10.1101/431833 — neuroscience — Posted on 2019-03-12

2134 The effects of habits on motor skill learning

Popp, N. J.; Yokoi, A.; Gribble, P. L.; Diedrichsen, J.

10.1101/338749 — neuroscience — Posted on 2019-03-12

2135 Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators

Tzilivaki, A.; Kastellakis, G.; Poirazi, P.

10.1101/251314 — neuroscience — Posted on 2019-03-12

2136 Preliminary evidence that maternal immune activation specifically increases diagonal domain volume in the rat brain during early postnatal development

Wood, T. C.; Edye, M. E.; Harte, M. K.; Neill, J. C.; Prinssen, E. P.; Vernon, A. C.

10.1101/432450 — neuroscience — Posted on 2019-03-12

2137 Infection with a small intestinal helminth Heligmosomoides polygyrus bakeri consistently alters microbial communities throughout the small and large intestine

Harris, N.; Rapin, A.; Chuat, A.; Zaiss, M.; Lebon, L.; Marsland, B.

10.1101/575787 — microbiology — Posted on 2019-03-12

2138 Establishment of an orthodontic retention mouse model and the effect of anti-c-Fms antibody on orthodontic relapse

Qi, J.; Kitaura, H.; Shen, W.-r.; Kishikawa, A.; Ogawa, S.; Ohori, F.; Noguchi, T.; Marahleh, A.; Nara, Y.; Mizoguchi, I.

10.1101/575589 — immunology — Posted on 2019-03-12

2139 Impact of Direct Acting Antivirals on Survival in Patients with Chronic Hepatitis C and Hepatocellular Carcinoma

Kamp, W. M.; Sellers, C. M.; Stein, S. M.; Lim, J. K.; Kim, H. S.

10.1101/575670 — immunology — Posted on 2019-03-12

2140 CNEr: a toolkit for exploring extreme noncoding conservation

Tan, G.; Polychronopoulos, D.; Lenhard, B.

10.1101/575704 — genomics — Posted on 2019-03-12

2141 A RID-like cytosine methyltransferase homologue controls sexual development in the fungus Podospora anserina

Grognet, P.; Timpano, H.; Carlier, F.; Aït-Benkhali, J.; Berteaux-Lecellier, V.; Debuchy, R.; Bidard, F.; Malagnac, F.

10.1101/575746 — genetics — Posted on 2019-03-12

2142 Potential risk factors associated with human cystic echinococcosis: a semi-structured questionnaire from a large population-based ultrasound cross-sectional study in Eastern Europe and Turkey

Tamarozzi, F.; Akhan, O.; Cretu, C. M.; Vutova, K.; Fabiani, M.; Orsten, S.; Pezzotti, P.; Popa, L. G.; Velev, V.; Siles-Lucas, M.; Brunetti, E.; Casulli, A.

10.1101/575761 — epidemiology — Posted on 2019-03-12

2143 MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells

Gad, H.; Mortusewicz, O.; Rudd, S. G.; Stolz, A.; Amaral, N.; Brautigam, L.; Pudelko, L.; Sanjiv, K.; Kalderen, C.; Jemth, A.-S.; Almlof, I.; Visnes, T.; Schultz, N.; Bostrom, J.; Calderon Montano, J. M.; Hagenkort, A.; Groth, P.; Loseva, O.; Gokturk, C.; Koolmeister, T.; Wakchaure, P.; Homan, E.; Strom, C. E.; Scobie, M.; Bastians, H.; Warpman Berglund, U.; Helleday, T.

10.1101/575290 — cancer biology — Posted on 2019-03-12

2144 Bistability and oscillations in cooperative microtubule and kinetochore dynamics in the mitotic spindle

Schwietert, F.; Kierfeld, J.

10.1101/575530 — biophysics — Posted on 2019-03-12

2145 Difference contact maps: from what to why in the analysis of the conformational flexibility of proteins

Iyer, M.; Li, Z.; Jaroszewski, L.; Sedova, M.; Godzik, A.

10.1101/575696 — bioinformatics — Posted on 2019-03-12

2146 Association between hot flashes severity and oxidative stress among Mexican postmenopausal women: a cross-sectional study

Sanchez-Rodriguez, M. A.; Zacarias-Flores, M.; Arronte-Rosales, A.; Mendoza-Nunez, V. M.

10.1101/575621 — biochemistry — Posted on 2019-03-12

2147 XPO1 gene therapy restores cardiac function in rats with chronic induced myocardial infarction

Garcia-Manzanares, M.; Gil-Cayuela, C.; Martinez-Dolz, L.; Gonzalez Juanatey, J. R.; Lago, F.; Portoles, M.; Rosello-Lleti, E.; Rivera, J. M.

10.1101/575340 — molecular biology — Posted on 2019-03-12

2148 WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling

Song, Z.; Sun, X.; Xia, Z.; Jia, Y.; Zhu, J.; Fang, C.; Yang, H.; Wang, J.

10.1101/575100 — bioinformatics — Posted on 2019-03-12

2149 The fitness cost and benefit of phase separated protein deposits

Sanchez de Groot, N.; Torrent Burgas, M.; Ravarani, C. N. J.; Trusina, A.; Ventura, S.; Babu, M.

10.1101/574657 — systems biology — Posted on 2019-03-12

2150 Overexpression of the Rieske FeS protein of the Cytochrome b6f complex increases C4 photosynthesis

Ermakova, M.; Lopez-Calcagno, P. E.; Raines, C. A.; Furbank, R. T.; von Caemmerer, S.

10.1101/574897 — plant biology — Posted on 2019-03-12

2151 Conserved residues in the wheat (Triticum aestivum) NAM-A1 NAC domain are required for protein binding and when mutated lead to delayed peduncle and flag leaf senescence

Harrington, S. A.; Overend, L. E.; Cobo, N.; Borrill, P.; Uauy, C.

10.1101/573881 — plant biology — Posted on 2019-03-12

2152 The role of strigolactones in regulation of stomatal conductance and plant-pathogen interactions in Arabidopsis thaliana

Kalliola, M.; Jakobson, L.; Davidsson, P.; Pennanen, V.; Waszczak, C.; Yarmolinsky, D.; Zamora, O.; Palva, E. T.; Kariola, T.; Kollist, H.; Brosche, M.

10.1101/573873 — plant biology — Posted on 2019-03-12

2153 Capsidiol, a defensive sesquiterpene produced by wild tobacco in response to attack from the fungal pathogen Alternaria alternata, is regulated by an ERF2-like transcription factor

Na, S.; Ma, L.; Wang, W.; Sun, H.; Wang, L.; Baldwin, I. T.; Wu, J.

10.1101/573675 — plant biology — Posted on 2019-03-12

2154 Effects of a demand optimization intervention on laboratory test utilization in primary care

Bucholc, M.; O'Kane, M.; O'Hare, B.; Mullan, C.; Cavanagh, P.; Ashe, S.

10.1101/573956 — pathology — Posted on 2019-03-12

2155 Root caries on a Paranthropus robustus third molar from Drimolen

Towle, I.; Riga, A.; Irish, J. D.; Dori, I.; Menter, C.; Moggi-Cecchi, J.

10.1101/573964 — paleontology — Posted on 2019-03-12

2156 Estimating statistical power for event-related potential studies using the late positive potential

Gibney, K. D.; Kypriotakis, G.; Cinciripini, P.; Robinson, J.; Minnix, J.; Versace, F.

10.1101/574368 — neuroscience — Posted on 2019-03-12

2157 Dopamine transients delivered in learning contexts do not act as model-free prediction errors

Sharpe, M. J.; Batchelor, H. M.; Mueller, L. E.; Chang, C. Y.; Maes, E. J. P.; Niv, Y.; Schoenbaum, G.

10.1101/574541 — neuroscience — Posted on 2019-03-12

2158 A computational model of intrathalamic signaling via open-loop thalamo-reticular-thalamic architectures

Brown, J. W.; Taheri, A.; Kenyon, R. V.; Berger-Wolf, T.; Llano, D. A.

10.1101/574178 — neuroscience — Posted on 2019-03-12

2159 Optimization of the navigated TMS mapping algorithm for accurate detection of plasticity and abnormalities in cortical muscle representations

Sinitsyn, D. O.; Chernyavskiy, A. Y.; Poydasheva, A. G.; Bakulin, I. S.; Suponeva, N. A.; Piradov, M. A.

10.1101/573220 — neuroscience — Posted on 2019-03-12

2160 Exploitation of the cooperative behaviours of anti-CRISPR phages

Chevallereau, A.; Meaden, S.; Fradet, O.; Landsberger, M.; Maestri, A.; Biswas, A.; Gandon, S.; van Houte, S.; Westra, E.

10.1101/574418 — microbiology — Posted on 2019-03-12

2161 Transcriptome profiling of mouse samples using nanopore sequencing of cDNA and RNA molecules

Sessegolo, C.; Cruaud, C.; Da Silva, C.; Dubarry, M.; Derrien, T.; Lacroix, V.; Aury, J.-M.

10.1101/575142 — bioinformatics — Posted on 2019-03-12

2162 Towards accurate high-throughput ligand affinity prediction by exploiting structural ensembles, docking metrics and ligand similarity

Schneider, M.; Pons, J.-L.; Bourguet, W.; Labesse, G.

10.1101/574517 — bioinformatics — Posted on 2019-03-12

2163 Anodal transcranial direct current stimulation reduces collinear lateral inhibition in normal peripheral vision

Nallour Raveendran, R.; Tsang, K.; Tiwana, D.; Thompson, B.

10.1101/574590 — neuroscience — Posted on 2019-03-12

2164 Forward modelling reveals dynamics of neural orientation tuning to unconscious visual stimuli during binocular rivalry

Tang, M. F.; Arabzadeh, E.; Mattingley, J. B.

10.1101/574905 — neuroscience — Posted on 2019-03-12

2165 A failed top-down control from prefrontal cortex to amygdala in generalized anxiety disorder: evidence from resting-state fMRI with Granger causality analysis

Dong, M.; Xia, L.; Lu, M.; Li, C.; Xu, K.; Zhang, L.

10.1101/573634 — neuroscience — Posted on 2019-03-12

2166 Structural Basis for the Clamping and Ca2+ Activation of SNARE-mediated Fusion by Synaptotagmin

Grushin, K.; Wang, J.; Coleman, J.; Rothman, J. E.; Sindelar, C. E.; Krishnakumar, S. S.

10.1101/574632 — neuroscience — Posted on 2019-03-12

2167 A practical computerized decision support system for predicting the severity of Alzheimer’s disease of an individual

Bucholc, M.; Ding, X.; Wang, H.; Glass, D.; Wang, H.; Prasad, G.; Maguire, L.; Bjourson, A.; McClean, P.; Todd, S.; Finn, D.; Wong-Lin, K.

10.1101/573899 — neuroscience — Posted on 2019-03-12

2168 Entrainment of local synchrony reveals a causal role for high-beta right frontal oscillations in human visual consciousness

Vernet, M.; Stengel, C.; Quentin, R.; Amengual, J. L.; Valero-Cabre, A.

10.1101/574939 — neuroscience — Posted on 2019-03-12

2169 Colocalization of MOR1 and GAD67 in Mouse Nucleus Accumbens

Hinkle, C. F.; Dedkov, E. I.; Buono, R. J.; Ferraro, T. N.

10.1101/574434 — neuroscience — Posted on 2019-03-12

2170 Dilated Saliency U-Net for White Matter Hyperintensities Segmentation using Irregularity Age Map

Jeong, Y.; Rachmadi, M. F.; Valdes Hernandez, M. d. C.; Komura, T.

10.1101/550517 — neuroscience — Posted on 2019-03-12

2171 Effects of dietary replacement of broiler litter with Melia azedarach foliage on productive performance, fatty acid composition and health-related fatty acid indices in beef fats from Nguni x Brahman steers fed sugarcane tops based diets

Mthiyane, D. M. N.; Dlamini, B. J.; Hugo, A.; Nsahlai, I. V.

10.1101/573667 — molecular biology — Posted on 2019-03-12

2172 The ubiquitin-conjugating enzyme Ubc13-Mms2 cooperates with a family of FYVE-type-RING ubiquitin protein ligases in K63-polyubiquitylation at internal membranes

Renz, C.; Troester, V.; Albert, T. K.; Santt, O.; Jacobs, S. C.; Khmelinskii, A.; Ulrich, H. D.

10.1101/575241 — molecular biology — Posted on 2019-03-12

2173 Structure elucidation of colibactin.

Xue, M.; Kim, C. S.; Healy, A. R.; Wernke, K. W.; Wang, Z.; Frischling, M. C.; Shine, E. E.; Wang, W.; Herzon, S. B.; Crawford, J. M.

10.1101/574053 — microbiology — Posted on 2019-03-12

2174 Dynamics of Mycobacterium tuberculosis Ag85B revealed by sensitive ELISA

Ernst, J.; Cornelius, A.; Bolz, M.

10.1101/574996 — microbiology — Posted on 2019-03-12

2175 Effects of graphene oxide and graphite on soil bacterial and fungal diversity

Forstner, C.; Orton, T. G.; Skarshewski, A.; Wang, P.; Kopittke, P. M.; Dennis, P. G.

10.1101/530485 — microbiology — Posted on 2019-03-12

2176 T Cell Receptor Immunotherapy Drives Human Immunodeficiency Virus Evolution in Humanized Mice

Joglekar, A. V.; Swift, M.; Leonard, M. T.; Jeppson, J. D.; Sandoval, S.; Baltimore, D.

10.1101/574608 — immunology — Posted on 2019-03-12

2177 Phased genome sequence of an interspecific hybrid flowering cherry, Somei-Yoshino (Cerasus x yedoensis)

Shirasawa, K.; Esumi, T.; Hirakawa, H.; Tanaka, H.; Itai, A.; Ghelfi, A.; Nagasaki, H.; Isobe, S.

10.1101/573451 — genomics — Posted on 2019-03-12

2178 Characterisation of l(3)tb as a novel tumour suppressor allele of DCP2 in Drosophila melanogaster

Mishra, R.; Kunar, R.; MANDAL, L.; Alone, D. P.; Chandrasekharan, S.; Tiwari, A. K.; Mukherjee, A.; Tapadia, M. G.; Roy, J. K.

10.1101/574707 — genetics — Posted on 2019-03-12

2179 Genetic analysis identifies molecular systems and biological pathways associated with household income

Hill, W. D.; Davies, N. M.; Ritchie, S. J.; Skene, N. G.; Bryois, J.; Bell, S.; Di Angelantonio, E.; Roberts, D. J.; Xueyi, S.; Davies, G.; Liewald, D. C. M.; Porteous, D. J.; Hayward, C.; Butterworth, A. S.; McIntosh, A. M.; Gale, C. R.; Deary, I. J.

10.1101/573691 — genetics — Posted on 2019-03-12

2180 Metformin rescues muscle function in BAG3 myofibrillar myopathy models

Ruparelia, A. A.; McKaige, E. A.; Williams, C.; Schulze, K. E.; Fuchs, M.; Oorschot, V.; Lacene, E.; Mirella, M.; Baxter, E. C.; TORRENTE, Y.; Ramm, G.; Stojkovic, T.; Lavoie, J. N.; Bryson-Richardson, R. J.

10.1101/574806 — genetics — Posted on 2019-03-12

2181 Mean-field computational approach to HIV dynamics on a fitness landscape

Chen, H.; Kardar, M.

10.1101/518704 — evolutionary biology — Posted on 2019-03-12

2182 The bacterial endosymbiont Wolbachia increases reproductive investment and accelerates the life cycle of ant colonies

SINGH, R.; Linksvayer, T. A.

10.1101/574921 — evolutionary biology — Posted on 2019-03-12

2183 The structure of species discrimination signals across a primate radiation

Winters, S.; Allen, W. L.; Higham, J. P.

10.1101/574558 — evolutionary biology — Posted on 2019-03-12

2184 Phytoplasma SAP11 effector destabilization of TCP transcription factors differentially impact development and defence of Arabidopsis versus maize

Pecher, P.; Moro, G.; Canale, M. C.; Capdevielle, S.; Singh, A.; MacLean, A.; Sugio, A.; Kuo, C.-H.; Lopes, J. R. S.; Hogenhout, S. A.

10.1101/574319 — evolutionary biology — Posted on 2019-03-12

2185 Integrating natural history-derived phenomics with comparative genomics to study the genetic architecture of convergent evolution

Lamichhaney, S.; Card, D. C.; Grayson, P.; Tonini, J. F.; Bravo, G. A.; Napflin, K.; Garcia, F. T.; Torres, C.; Burbrink, F.; Clark, J. A.; Sackton, T. B.; Edwards, S. V.

10.1101/574756 — evolutionary biology — Posted on 2019-03-12

2186 Investigation of the validity of two Bayesian ancestral state reconstruction models for estimating Salmonella transmission during outbreaks

Bloomfield, S.; Vaughan, T.; Benschop, J.; Marshall, J.; Hayman, D.; Biggs, P.; Carter, P.; French, N.

10.1101/574087 — epidemiology — Posted on 2019-03-12

2187 Perceptions, attitudes and practices towards scabies in communities on the Bijagos Islands, Guinea-Bissau

Lopes, M. J.; Teixeira da Silva, E.; Ca, J.; Goncalves, A.; Rodrigues, A.; Mandjuba, C.; Nakutum, J.; D'Alessandro, U.; Achan, J.; Logan, J.; Bailey, R.; Walker, S.; Last, A.; Marks, M.

10.1101/574327 — epidemiology — Posted on 2019-03-12

2188 Relation of in-utero exposure to antiepileptic drugs to pregnancy duration and size at birth

Margulis, A. V.; Hernandez-Diaz, S.; McElrath, T.; Rothman, K. J.; Plana, E.; Almqvist, C.; D'Onofrio, B. M.; Oberg, A. S.

10.1101/574269 — epidemiology — Posted on 2019-03-12

2189 Best practices for making reliable inferences from citizen science data: case study using eBird to estimate species distributions

Johnston, A.; Hochachka, W. M.; Strimas-Mackey, M.; Ruiz Gutierrez, V.; Robinson, O. J.; Miller, E. T.; Auer, T.; Kelling, S. T.; Fink, D.

10.1101/574392 — ecology — Posted on 2019-03-12

2190 Regional climate affects salmon lice population dynamics, stage structure, and management

Hurford, A.; Wang, X.; Zhao, X.-Q.

10.1101/574830 — ecology — Posted on 2019-03-12

2191 Disrupting butterfly microbiomes does not affect host survival and development

Phalnikar, K.; Kunte, K.; Agashe, D.

10.1101/574871 — ecology — Posted on 2019-03-12

2192 Is microbial activity in tropical forests limited by phosphorus availability? Evidence from a tropical forest in China

Mori, T.; Lu, X.; Wang, C.; Mao, Q.; Wang, S.; Zhang, W.; Mo, J.

10.1101/575001 — ecology — Posted on 2019-03-12

2193 Satb2 regulates proliferation and nuclear integrity of pre-osteoblasts

Dowrey, T.; Schwager, E. E.; Duong, J.; Merkuri, F.; Zarate, Y. A.; Fish, J. L.

10.1101/574863 — developmental biology — Posted on 2019-03-12

2194 A pivotal genetic program controlled by thyroid hormone during the maturation of GABAergic neurons in mice

Richard, S.; Guyot, R.; Rey-Millet, M.; Prieux, M.; Markossian, S.; Aubert, D.; Flamant, F.

10.1101/574202 — developmental biology — Posted on 2019-03-12

2195 A novel, dynein-independent mechanism focuses the endoplasmic reticulum around spindle poles in dividing Drosophila spermatocytes

Karabasheva, D.; Smyth, J. T.

10.1101/574855 — cell biology — Posted on 2019-03-12

2196 Chaperone-Mediated Reflux of Secretory Proteins to the Cytosol During Endoplasmic Reticulum Stress

Igbaria, A.; Merksamer, P. I.; Trusina, A.; Tilahun, F.; Johnson, J. R.; Brandman, O.; Krogan, N. J.; Weissman, J. S.; Papa, F. R.

10.1101/562306 — cell biology — Posted on 2019-03-12

2197 Size-Dependent Secretory Protein Reflux into the Cytosol in Association with Acute Endoplasmic Reticulum Stress

Snapp, E.; Lajoie, P.

10.1101/573428 — cell biology — Posted on 2019-03-12

2198 Cultured pluripotent planarian stem cells retain potency and express proteins from exogenously introduced mRNAs

Sanchez Alvarado, A.; Lei, K.; McKinney, S. A.; Ross, E. J.; Lee, H.-C.

10.1101/573725 — cell biology — Posted on 2019-03-12

2199 C3G (RapGEF1) localizes to the mother centriole and regulates centriole division and primary cilia dynamics

Nayak, S. C.; Radha, V.

10.1101/575225 — cell biology — Posted on 2019-03-12

2200 Modeling non-genetic dynamics of cancer cell states measured by single-cell analysis: Uncovering bifurcations that explain why treatment either kills a cancer cell or makes it resistant

Huang, S.

10.1101/574848 — cancer biology — Posted on 2019-03-12

2201 MTH1 inhibitor TH588 induces mitosis-dependent accumulation of genomic 8-oxodG and disturbs mitotic progression

Rudd, S. G.; Gad, H.; Amaral, N.; Hagenkort, A.; Groth, P.; Strom, C. E.; Mortusewicz, O.; Warpman-Berglund, U.; Helleday, T.

10.1101/573931 — cancer biology — Posted on 2019-03-12

2202 Heterogeneous loop model to infer 3D chromosome structures from Hi-C

Liu, L.; Kim, M. H.; Hyeon, C.

10.1101/574970 — biophysics — Posted on 2019-03-12

2203 The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing

Podgurskaya, A.; Tsvelaya, V.; Slotvitsky, M.; Dementyeva, E.; Valetdinova, K.; Agladze, K.

10.1101/574012 — biophysics — Posted on 2019-03-12

2204 Multivariate pattern classification on BOLD activation pattern induced by deep brain stimulation in motor, associative, and limbic brain networks

Cho, S.; Min, H.-K.; Gibson, W.; In, M.-H.; Lee, K. H.; Jo, H. J.

10.1101/574889 — bioinformatics — Posted on 2019-03-12

2205 Deep Learning of Representations for Transcriptomics-based Phenotype Prediction

Smith, A. M.; Walsh, J. R.; Long, J.; Davis, C. B.; Henstock, P.; Hodge, M. R.; Maciejewski, M.; Mu, X. J.; Ra, S.; Zhang, S.; Ziemek, D.; Fisher, C. K.

10.1101/574723 — bioinformatics — Posted on 2019-03-12

2206 conLSH: Context based Locality Sensitive Hashing for Mapping of noisy SMRT Reads

Chakraborty, A.; Bandyopadhyay, S.

10.1101/574467 — bioinformatics — Posted on 2019-03-12

2207 PHi-C: deciphering Hi-C data into polymer dynamics

Shinkai, S.; Nakagawa, M.; Sugawara, T.; Togashi, Y.; Ochiai, H.; Nakato, R.; Taniguchi, Y.; Onami, S.

10.1101/574962 — bioinformatics — Posted on 2019-03-12

2208 Genome-wide profiling of microRNAs and prediction of mRNA targets in 17 bovine tissues

Wang, M.; Chamberlain, A. J.; Prowse-Wilkins, C. P.; Vander Jagt, C. J.; Hancock, T. P.; Pryce, J. E.; Cocks, B. G.; Goddard, M. E.; Hayes, B. J.

10.1101/574954 — bioinformatics — Posted on 2019-03-12

2209 SNP Identity Searching Across Ethnicities, Kinship, and Admixture

Helfer, B. S.; Ricke, D. O.

10.1101/574566 — bioinformatics — Posted on 2019-03-12

2210 Computational Inference Software for Tetrad Assembly from Randomly Arrayed Yeast Colonies

Sakhanenko, N. A.; Cromie, G.; Dudley, A. M.; Galas, D. J.

10.1101/574376 — bioinformatics — Posted on 2019-03-12

2211 Selective labelling of arginine residues engaged in binding sulfatedglycosaminoglycans

Bui, P. T.; li, y.; Sarsby, J.; Nunes, Q.; Wilkinson, M.; Fernig, D.

10.1101/574947 — biochemistry — Posted on 2019-03-12

2212 Primary care use of laboratory tests in Northern Ireland Western Health and Social Care Trust: a cross-sectional study

Bucholc, M.; O'Kane, M.; Mullan, C.; Ashe, S.; Maguire, L.

10.1101/573949 — biochemistry — Posted on 2019-03-12

2213 Endothelial PKA targets ATG16L1 to regulate angiogenesis by limiting autophagy

Zhao, X.; Nedvetsky, P.; Vion, A.-C.; Popp, O.; Zühlke, K.; Dittmar, G.; Klussmann, E.; Gerhardt, H.

10.1101/573683 — biochemistry — Posted on 2019-03-12

2214 Long-tailed macaques extract statistical information from repeated types of events to make rational decisions under uncertainty

Placi, S.; Padberg, M.; Rakoczy, H.; Fischer, J.

10.1101/574475 — animal behavior and cognition — Posted on 2019-03-12

2215 The Life History of Human Foraging: Cross-Cultural and Individual Variation

Koster, J.; McElreath, R.; Hill, K.; Yu, D.; Shepard, G.; van Vliet, N.; Gurven, M.; Kaplan, H.; Trumble, B.; Bliege Bird, R.; Bird, D.; Codding, B.; Coad, L.; Pacheco-Cobos, L.; Winterhalder, B.; Lupo, K.; Schmitt, D.; Sillitoe, P.; Franzen, M.; Alvard, M.; Venkataraman, V.; Kraft, T.; Endicott, K.; Beckerman, S.; Marks, S.; Headland, T.; Pangau-Adam, M.; Siren, A.; Kramer, K.; Greaves, R.; Reyes-Garcia, V.; Gueze, M.; Duda, R.; Fernandez-Llamazares, A.; Gallois, S.; Napitupulu, L.; Ellen, R.; Ziker, J.; Nielsen, M.; Ready, E.; Healey, C.; Ross, C.

10.1101/574483 — animal behavior and cognition — Posted on 2019-03-12

2216 Bioelectrical signaling via domain wall migration

McNamara, H. M.; Salegame, R.; Al Tanoury, Z.; Xu, H.; Begum, S.; Ortiz, G.; Pourquie, O.; Cohen, A. E.

10.1101/570440 — biophysics — Posted on 2019-03-12

2217 Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis

Ashouri, J.; Hsu, L.-Y.; Yu, S.; Rychkov, D.; Chen, Y.; Chang, D.; Sirota, M.; Hansen, E.; Lattanza, L.; Zikherman, J.; Weiss, A.

10.1101/474700 — immunology — Posted on 2019-03-12

2218 Regulation of cerebrospinal fluid and brain tissue sodium levels by choroid plexus and brain capillary endothelial cell sodium-potassium pumps during migraine

Ghaffari, H.; Grant, S. C.; Petzold, L. R.; Harrington, M. G.

10.1101/572727 — systems biology — Posted on 2019-03-12

2219 TrkB Activation During a Critical Period Mimics the Protective Effects of Early Visual Experience on Perception and the Stability of Receptive Fields in Adult Superior Colliculus

Mudd, D. B.; Balmer, T. S.; Kim, S. Y.; Machhour, N.; Pallas, S. L.

10.1101/435784 — neuroscience — Posted on 2019-03-12

2220 Cascaded-CNN: Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps

Moritz, S.; Pfab, J.; Si, D.; Wu, T.; Hou, J.; Cheng, J.; Cao, R.; Wang, L.

10.1101/572990 — molecular biology — Posted on 2019-03-12

2221 Revealing evolutionary constraints on proteins through sequence analysis

Wang, S.-W.; Bitbol, A.-F.; Wingreen, N. S.

10.1101/397521 — biophysics — Posted on 2019-03-12

2222 The protein repertoire in early vertebrate embryogenesis

Peshkin, L.; Lukyanov, A.; Kalocsay, M.; Gage, R. M.; Wang, D.; Pells, T. J.; Karimi, K.; Vize, P. D.; Wuhr, M.; Kirschner, M. W.

10.1101/571174 — developmental biology — Posted on 2019-03-11

2223 G1/S transcription factors assemble in discrete clusters that increase in number as cells grow

Black, L.; Tollis, S.; Fiche, J.-B.; Dorsey, S.; Cheng, J.; Notley, S.; Crevier, B.; Bigness, J.; Nollmann, M.; Tyers, M.; Royer, C. A.

10.1101/574772 — cell biology — Posted on 2019-03-11

2224 Auxin-sensitive Aux/IAA proteins mediate drought tolerance in Arabidopsis by regulating glucosinolate levels

Salehin, M.; Li, B.; Tang, M.; Katz, E.; Song, L.; Ecker, J.; Kliebenstein, D.; Estelle, M.

10.1101/572305 — plant biology — Posted on 2019-03-11

2225 Mitogen-Activated Protein Kinase-Dependent Fiber-Type Regulation in Skeletal Muscle

Boyer, J. G.; Song, T.; Lee, D.; Fu, X.; Sadayappan, S.; Molkentin, J. D.

10.1101/361600 — developmental biology — Posted on 2019-03-11

2226 Altered structural brain asymmetry in autism spectrum disorder: large-scale analysis via the ENIGMA Consortium

Postema, M. C.; van Rooij, D.; Anagnostou, E.; Arango, C.; Auzias, G.; Behrmann, M.; Filho, G. B.; Calderoni, S.; Calvo, R.; Daly, E.; Deruelle, C.; Di Martino, A.; Dinstein, I.; Duran, F. L. S.; Durston, S.; Ecker, C.; Ehrlich, S.; Fair, D.; Fedor, J.; Feng, X.; Fitzgerald, J.; Floris, D. L.; Freitag, C. M.; Gallagher, L.; Glahn, D. C.; Gori, I.; Haar, S.; Hoekstra, L.; Jahansad, N.; Jalbrzikowski, M.; Janssen, J.; King, J. A.; Zaro, L. L.; Lerch, J. P.; Luna, B.; Martinho, M. M.; McGrath, J.; Medland, S. E.; Muratori, F.; Murphy, C. M.; Murphy, D. G. M.; O'Hearn, K.; Oranje, B.; Parellada,

10.1101/570655 — neuroscience — Posted on 2019-03-11

2227 Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins

Tyssowski, K. M.; Gray, J. M.

10.1101/572370 — neuroscience — Posted on 2019-03-11

2228 Simultaneous mesoscopic Ca2+ imaging and fMRI: Neuroimaging spanning spatiotemporal scales

Lake, E. M.; Ge, X.; Shen, X.; Herman, P.; Hyder, F.; Cardin, J. A.; Higley, M. J.; Scheinost, D.; Papademetris, X.; Crair, M. C.; Constable, R. T.

10.1101/464305 — neuroscience — Posted on 2019-03-11

2229 Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders

Mondo, E.; Barone, M.; Soverini, M.; D'Amico, F.; Marliani, G.; Cocchi, M.; Mattioli, M.; Candela, M.; Accorsi, P. A.

10.1101/573865 — microbiology — Posted on 2019-03-11

2230 Transcriptional profiling reveals running promotes cerebrovascular remodeling in young but not aged mice

Foley, K. E.; Yang, S.; Graham, L. C.; Howell, G. R.

10.1101/574673 — genomics — Posted on 2019-03-11

2231 Genetic structure is stronger across human-impacted habitats than among islands in the coral Porites lobata

Tisthammer, K. H.; Forsman, Z. H.; Toonen, R. J.; Richmond, R. H.

10.1101/574665 — genetics — Posted on 2019-03-11

2232 Cross-disorder genetic analyses implicate dopaminergic signaling as a biological link between Attention-Deficit/Hyperactivity Disorder and obesity measures

Mota, N. R.; Poelmans, G.; Klein, M.; Torrico, B.; Fernandez-Castillo, N.; Cormand, B.; Reif, A.; Franke, B.; Arias-Vasquez, A.

10.1101/573808 — genetics — Posted on 2019-03-11

2233 The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs

Marchant, A.; Cisneros, A.; Dube, A. K.; Gagnon-Arsenault, I.; Ascencio, D.; Jain, H.; Aube, S.; Eberlein, C.; Evans-Yamamoto, D.; Yachie, N.; Landry, C. R.

10.1101/564401 — evolutionary biology — Posted on 2019-03-11

2234 Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria

Ajogbasile, F. V.; Oguzie, J. U.; Oluniyi, P. E.; Eromon, P.; Uwanibe, J.; Mehta, S. B.; Siddle, K. J.; Odia, I.; Winnicki, S. M.; Akpede, N.; Akpede, G.; Okogbenin, S.; MacInnis, B. L.; Folarin, O. A.; Schaffner, S. F.; Ogbaini-Emovon, E.; Tomori, O.; Ihekweazu, C.; Sabeti, P. C.; Happi, C. T.

10.1101/572354 — genomics — Posted on 2019-03-11

2235 Interpretable classification of Alzheimer’s disease pathologies with a convolutional neural network pipeline

Tang, Z.; Chuang, K. V.; DeCarli, C.; Jin, L.-W.; Beckett, L.; Keiser, M. J.; Dugger, B. N.

10.1101/454793 — pathology — Posted on 2019-03-11

2236 The Neural Basis of Shared Preference Learning

Farmer, H.; Hamilton, A.; Hertz, U.

10.1101/570762 — neuroscience — Posted on 2019-03-11

2237 Short translational ramp determines efficiency of protein synthesis

Verma, M.; Choi, J.; Cottrell, K. A.; Lavagnino, Z.; Thomas, E. N.; Pavlovic Djuranovic, S.; Szczesny, P.; Piston, D. W.; Zaher, H.; Puglisi, J. D.; Djuranovic, S.

10.1101/571059 — molecular biology — Posted on 2019-03-11

2238 A comprehensive atlas of immunological differences between humans, mice and non-human primates

Bjornson, Z.; Fragiadakis, G. K.; Spitzer, M. H.; Madhireddy, D.; McIlwain, D.; Nolan, G. P.

10.1101/574160 — immunology — Posted on 2019-03-11

2239 The genome of Drosophila innubila reveals lineage-specific patterns of selection in immune genes

Hill, T.; Koseva, B.; Unckless, R. L.

10.1101/383877 — genomics — Posted on 2019-03-11

2240 Single cell expression variability in highly homogeneous populations of human cells is widespread, heritable, and implies cell function

Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J.

10.1101/574426 — genetics — Posted on 2019-03-11

2241 Karyotypic divergence confounds cellular phenotypes in large pharmacogenomic studies

Quevedo, R.; El-Hachem, N.; Smirnov, P.; Safikhani, Z.; Pugh, T. J.; Haibe-Kains, B.

10.1101/574350 — cancer biology — Posted on 2019-03-11

2242 Scalable methods for analyzing and visualizing phylogenetic placement of metagenomic samples

Czech, L.; Stamatakis, A.

10.1101/346353 — bioinformatics — Posted on 2019-03-11

2243 MoMI-G: Modular Multi-scale Integrated Genome Graph Browser

Yokoyama, T. T.; Sakamoto, Y.; Seki, M.; Suzuki, Y.; Kasahara, M.

10.1101/540120 — bioinformatics — Posted on 2019-03-11

2244 Inhibition of nucleotide synthesis mediates replicative senescence of human mammary epithelial cells

Delfarah, A.; Parrish, S.; Junge, J. A.; Yang, J.; Seo, F.; Li, S.; Wang, P.; Fraser, S. E.; Graham, N.

10.1101/423665 — systems biology — Posted on 2019-03-11

2245 A geometric attractor mechanism for self-organization of entorhinal grid modules

Kang, L.; Balasubramanian, V.

10.1101/338087 — neuroscience — Posted on 2019-03-11

2246 The influence of kinesthetic motor imagery and effector specificity on the long-latency stretch response

Forgaard, C.; Franks, I. M.; Maslovat, D.; Chua, R.

10.1101/510271 — neuroscience — Posted on 2019-03-11

2247 Evaluation of Enhanced Learning Techniques for Segmenting Ischaemic Stroke Lesions in Brain Magnetic Resonance Perfusion Images using a Convolutional Neural Network Scheme

Malla, C. U. P.; Valdes Hernandez, M. d. C.; Rachmadi, M. F.; Komura, T.

10.1101/544858 — neuroscience — Posted on 2019-03-11

2248 Revealing metabolic flexibility of Candidatus Accumulibacter phosphatis through redox cofactor analysis and metabolic network modeling

Guedes da Silva, L.; Olavarria Gamez, K.; Castro Gomes, J.; Akkermans, K.; Welles, L.; Abbas, B.; van Loosdrecht, M. C. M.; Wahl, S. A.

10.1101/458331 — microbiology — Posted on 2019-03-11

2249 Leishmania major degrades murine CXCL1 - an immune evasion strategy

Yorek, M. S.; Poudel, B.; Mazgaeen, L.; Pope, R. M.; Wilson, M. E.; Gurung, P.

10.1101/571141 — microbiology — Posted on 2019-03-11

2250 Feature Selection and Dimension Reduction for Single Cell RNA-Seq based on a Multinomial Model

Townes, F. W.; Hicks, S. C.; Aryee, M. J.; Irizarry, R. A.

10.1101/574574 — genomics — Posted on 2019-03-11

2251 Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

Tam, O.; Rozhkov, N. V.; Shaw, R.; Kim, D.; Hubbard, I.; Fennessey, S.; Propp, N.; The NYGC ALS Consortium, ; Fagegaltier, D.; Ostrow, L. W.; Phatnani, H.; Ravits, J.; Dubnau, J.; Gale Hammell, M.

10.1101/574509 — genomics — Posted on 2019-03-11

2252 The transferability of lipid loci across African, Asian and European cohorts

Telkar, N.; Reiker, T.; Walters, R. G.; Lin, K.; Eriksson, A.; Gurdasani, D.; Gilly, A.; Southam, L.; Tsafantakis, E.; Karaleftheri, M.; Seeley, J.; Kamali, A.; Asiki, G.; Millwood, I. Y.; Holmes, M.; Du, H.; Guo, Y.; Understanding Society Scientific Group, ; Kumari, M.; Dedoussis, G.; Li, L.; Chen, Z.; Sandhu, M.; Zeggini, E.; Kuchenbaecker, K.

10.1101/525170 — genetics — Posted on 2019-03-11

2253 TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits

Nagpal, S.; Meng, X.; Epstein, M. P.; Tsoi, L. C.; Patrick, M.; Gibson, G.; De Jager, P.; Bennett, D. A.; Wingo, A. P.; Wingo, T. S.; Yang, J.

10.1101/507525 — genetics — Posted on 2019-03-11

2254 Combination image flow cytometry for single-cell analysis reveals novel methods for isolating subsets of megakaryocyte progenitor populations

Bush, L. M.; Healy, C. P.; Marvin, J. E.; Deans, T. L.

10.1101/512442 — cell biology — Posted on 2019-03-11

2255 Identifying chemogenetic interactions from CRISPR knockout screens with drugZ

Colic, M.; Wang, G.; Zimmermann, M.; Mascall, K.; McLaughlin, M.; Bertolet, L.; Lenoir, W. F.; Moffat, J.; Angers, S.; Durocher, D.; Hart, T.

10.1101/232736 — bioinformatics — Posted on 2019-03-11

2256 A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes

Soneson, C.; Yao, Y.; Bratus-Neuenschwander, A.; Patrignani, A.; Robinson, M. D.; Hussain, S.

10.1101/574525 — bioinformatics — Posted on 2019-03-11

2257 Alzheimer disease and Apolipoprotein E4: meningeal brain lymphatics point to new clues in pathogenesis

Chrousos, G. P.; Mentis, A.

10.1101/571729 — neuroscience — Posted on 2019-03-11

2258 The invasion of de-differentiating cancer cells into hierarchical tissues

Zhou, D.; Luo, Y.; Dingli, D.; Traulsen, A.

10.1101/574251 — evolutionary biology — Posted on 2019-03-11

2259 The TLR5 agonist flagellin modifies phenotypical and enhances functional activation of lung mucosal antigen presenting cells in neonatal mice

Sharma, P.; Levy, O.; Dowling, D. J.

10.1101/564054 — immunology — Posted on 2019-03-11

2260 De-novo variants in XIRP1 associated with polydactyly and polysyndactyly in Holstein cattle

Braun, M.; Hellige, M.; Gerhauser, I.; Ciurkiewicz, M.; Lehmbecker, A.; Beineke, A.; Baumgaertner, W.; Metzger, J.; Distl, O.

10.1101/574061 — genetics — Posted on 2019-03-11

2261 Single cell expression variability in highly homogeneous populations of human cells is widespread, heritable, and implies cell function

Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J.

10.1101/574426 — genetics — Posted on 2019-03-11

2262 Sequential compression across latent space dimensions enhances gene expression signatures

Way, G. P.; Zietz, M.; Himmelstein, D. S.; Greene, C. S.

10.1101/573782 — bioinformatics — Posted on 2019-03-11

2263 Learning-accelerated Discovery of Immune-Tumour Interactions

Ozik, J.; Collier, N.; Heiland, R.; Macklin, P.

10.1101/573972 — systems biology — Posted on 2019-03-11

2264 Low temperature triggers genome-wide hypermethylation of transposable elements and centromeres in maize

ACHOUR, Z.; JOETS, J.; LEGUILLOUX, M.; SELLIER, H.; PICHON, J.-P.; LEVEUGLE, M.; DUBORJAL, H.; CAIUS, J.; BRUNAUD, V.; PAYSANT-LE ROUX, C.; MARY-HUARD, T.; GIAUFFRET, C.; VITTE, C.

10.1101/573915 — plant biology — Posted on 2019-03-11

2265 Cingulate Cortex Atrophy is Associated with Hearing Loss in Presbycusis with Cochlear Amplifier Dysfunction

Belkhiria, C.; Vergara, R. C.; San Martin, S.; Leiva, A.; Marcenaro, B.; Martinez, M.; Delgado, C.; Delano, P. H.

10.1101/574228 — neuroscience — Posted on 2019-03-11

2266 Recombination-independent recognition of DNA homology for meiotic silencing in Neurospora crassa

Rhoades, N.; Cecere, G.; Hammond, T.; Gladyshev, E.

10.1101/573907 — molecular biology — Posted on 2019-03-11

2267 Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans

Shomer, N.; Kadhim, A. Z.; Grants, J. M.; Cheng, X.; Poon, A. F.-Y.; Lee, M. Y. Y.; Bhanshali, F.; Muhuri, A.; Park, J. I.; Lee, D.; Lee, S.-J. V.; Lynn, F. C.; Taubert, S.

10.1101/565739 — genetics — Posted on 2019-03-11

2268 MicroRNA Overexpression screen reveals a noncanonical role of CDK2 in regulating neutrophil migration

Hsu, A. Y.; Wang, D.; Liu, S.; Lu, J.; Sobreira, R. S.; Bennin, D. A.; Huttenlocher, A.; Wan, J.; Deng, Q.

10.1101/574335 — immunology — Posted on 2019-03-11

2269 Molecular and anatomical organization of the dorsal raphe nucleus

Huang, K. W.; Ochandarena, N. E.; Philson, A. C.; Hyun, M.; Birnbaum, J. E.; Cicconet, M.; Sabatini, B. L.

10.1101/573923 — neuroscience — Posted on 2019-03-11

2270 iEDGE: integration of Epi-DNA and Gene Expression and applications to the discovery of somatic copy number-associated drivers in cancer

Li, A.; Chapuy, B.; Varelas, X.; Sebastiani, P.; Monti, S.

10.1101/573824 — bioinformatics — Posted on 2019-03-11

2271 Identification of metabolites from tandem mass spectra with a machine learning approach utilizing structural features

Li, Y.; Kuhn, M.; Gavin, A.-C.; Bork, P.

10.1101/573790 — bioinformatics — Posted on 2019-03-11

2272 Immediate and deferred epigenomic signature of neuronal activation

Fernandez-Albert, J.; Lipinski, M.; Lopez-Cascales, M. T.; Rowley, M. J.; Martin-Gonzalez, A. M.; del Blanco, B.; Corces, V.; Barco, A.

10.1101/534115 — neuroscience — Posted on 2019-03-11

2273 Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells

Comoglio, F.; Simonatto, M.; Polletti, S.; Liu, X.; Smale, S. T.; Barozzi, I.; Natoli, G.

10.1101/573832 — genomics — Posted on 2019-03-11

2274 Proteome of the secondary plastid of Euglena gracilis reveals metabolic quirks and colourful history

Novak Vanclova, A. M.; Zoltner, M.; Kelly, S.; Soukal, P.; Zahonova, K.; Füssy, Z.; Ebenezer, T. E.; Lacova Dobakova, E.; Elias, M.; Lukes, J.; Field, M. C.; Hampl, V.

10.1101/573709 — evolutionary biology — Posted on 2019-03-11

2275 Developmental transcriptomes of the sea star, Patiria miniata, illuminate the relationship between conservation of gene expression and morphological conservation

Gildor, T.; Cary, G.; Lalzar, M.; Hinman, V.; Ben-Tabou de-Leon, S.

10.1101/573741 — evolutionary biology — Posted on 2019-03-11

2276 ComplexBrowser: a tool for identification and quantification of protein complexes in large scale proteomics datasets

Michalak, W.; Tsiamis, V.; Schwammle, V.; Rogowska-Wrzesinska, A.

10.1101/573774 — bioinformatics — Posted on 2019-03-11

2277 An equilibrium binding model for CpG DNA-dependent dimerization of Toll-like receptor 9

Reikine, S.; McLaughlin, S. H.; Johnson, C. M.; Modis, Y.

10.1101/573238 — biochemistry — Posted on 2019-03-11

2278 PRDM16 establishes lineage-specific transcriptional program to promote temporal progression of neural progenitors in the mouse neocortex

He, L.; Jones, J.; He, W.; Bjork, B.; Wen, J.; Dai, Q.

10.1101/573857 — developmental biology — Posted on 2019-03-11

2279 Motor context coordinates visually guided walking in Drosophila

Cruz, T. L.; Fujiwara, T. E.; Varela, N.; Mohammad, F.; Claridge-Chang, A.; Chiappe, M. E.

10.1101/572792 — neuroscience — Posted on 2019-03-11

2280 Sensitivity of Olfactory Sensory Neurons to food cues is tuned to nutritional states by Neuropeptide Y signalling

Kaniganti, T.; Deopgade, A.; Maduskar, A.; Mukherjee, A.; Guru, A.; Subhedar, N.; Ghose, A.

10.1101/573170 — neuroscience — Posted on 2019-03-11

2281 Metabolic constraints drive self-organization of specialized cell groups

Varahan, S.; Walvekar, A.; Sinha, V.; Krishna, S.; Laxman, S.

10.1101/573626 — cell biology — Posted on 2019-03-11

2282 Differential modulation of mouse heart gene expression by infection with two Trypanosoma cruzi strains: a transcriptome analysis

Rezende de Castro, T. B.; Campos Canesso, M. C.; Boroni, M.; Chame, D. F.; de Laet Souza, D.; Toledo, N. E.; Tahara, E. B.; Pena, S. D.; Machado, C. R.; Chiari, E.; Macedo, A. M.; Franco, G. R.

10.1101/574343 — bioinformatics — Posted on 2019-03-11

2283 A mathematical model of Campylobacter dynamics within a broiler flock

Rawson, T.; Stamp Dawkins, M.; Bonsall, M.

10.1101/574301 — systems biology — Posted on 2019-03-11

2284 Development of a model estimating root length density from root impacts on a soil profile in pearl millet (Pennisetum glaucum (L.) R. Br). Application to measure root system response to water stress in field conditions

Faye, A.; Sine, B.; Chopart, J.-L.; Grondin, A.; Lucas, M.; Diedhiou, A. G.; Gantet, P.; Cournac, L.; Min, D.; Audebert, A.; Kane, A.; Laplaze, L.

10.1101/574285 — plant biology — Posted on 2019-03-11

2285 Multimorbidity and healthcare utilization: A register-based study in Denmark

Frolich, A.; Ghith, N.; Schiotz, M.; Jacobsen, R.; Stockmarr, A.

10.1101/574293 — epidemiology — Posted on 2019-03-11

2286 Quadriceps and hamstrings coactivation in exercises used in prevention and rehabilitation of hamstring strain injury in young soccer players

Torres, G.; Chorro, D.; Navandar, A.; Rueda, J.; Fernandez, L.; Navarro, E.

10.1101/574210 — scientific communication and education — Posted on 2019-03-11

2287 Regional brain development analysis through registration using anisotropic similarity, a constrained affine transformation

Legouhy, A.; Commowick, O.; Proisy, M.; Rousseau, F.; Barillot, C.

10.1101/574129 — neuroscience — Posted on 2019-03-11

2288 In vitro evaluation of probiotic properties of lactic acid bacteria isolated from some traditionally fermented Ethiopian food products

Weldesiet, G. M. M.; Tesfaye, A.; Muleta, D.; Tessema, T. S.

10.1101/574194 — microbiology — Posted on 2019-03-11

2289 Procaine and S-adenosyl-L-homocysteine (SAH) affect the expression of genes related to the epigenetic machinery and change the DNA methylation status of in vitro cultured bovine skin fibroblasts

Schumann, N. A. B.; Mendonca, A. d. S.; Silveira, M. M.; Vargas, L. N.; Leme, L. O.; Sousa, R. V. d.; Franco, M. M.

10.1101/574186 — genetics — Posted on 2019-03-11

2290 A high-density genetic map and molecular sex-typing assay for gerbils

Brekke, T. D.; Supriya, S.; Denver, M.; Thom, A.; Steele, K. A.; Mulley, J. F.

10.1101/567016 — genetics — Posted on 2019-03-11

2291 Diet composition of introduced Barn Owls (Tyto alba javanica) in urban area in comparison with agriculture settings

Saufi, S.; Ravindran, S.; Hamid, N. H.; Zainal Abidin, C. M. R.; Ahmad, H.; Ahmad, A. H.; Salim, H.

10.1101/574277 — ecology — Posted on 2019-03-11

2292 A systematic review of MERS-CoV (Middle East Respiratory Syndrome Coronavirus) seroprevalence and viral RNA prevalence in dromedary camels: implications for animal vaccination

Dighe, A.; Jombart, T.; Van Kerkhove, M. D.; Ferguson, N.

10.1101/574103 — epidemiology — Posted on 2019-03-11

2293 Injection practices in 2011-2015: A rapid review using data from the Demographic and Health Surveys (DHS)

Hayashi, T.; Hutin, Y. J.-F.; Altaf, A.; Allegranzi, B.; Kaneko, S.; Bulterys, M.

10.1101/574137 — epidemiology — Posted on 2019-03-11

2294 Trait plasticity of intensive pasture species due to growth in mixture across seasons and nutrient addition levels

Mason, N. W. H.; Orwin, K.; Mudge, P.; Lambie, S.; Waugh, D.; Carmona, C. P.

10.1101/574145 — ecology — Posted on 2019-03-11

2295 Medication-related osteonecrosis of the jaws after tooth extraction in senescent female mice treated with zoledronic acid: microtomographic, histological and immunohistochemical characterization

Biguetti, C. C.; De Oliva, A. H.; Healy, K.; Mahmoud, R. H.; Custodio, I. D. C.; Constantino, D. H.; Ervolino, E.; Duarte, M. A. H.; Fakhouri, W. D.; Matsumoto, M. A.

10.1101/574111 — immunology — Posted on 2019-03-11

2296 Frequent sugar feeding behavior by Aedes aegypti in Bamako, Mali makes them ideal candidates for control with attractive toxic sugar baits (ATSB)

Sisoko, F.; Junnila, A.; Traore, M.; Traore, S. F.; Doumbia, S.; Dembele, S. M.; Schlein, Y.; Gergely, P.; Xue, R.-d.; Arheart, K. L.; Revay, E. E.; Kravchenko, V. D.; Beier, J. C.; Muller, G. C.

10.1101/574095 — ecology — Posted on 2019-03-11

2297 From root to tips: sporulation evolution and specialization in Bacillus subtilis and the intestinal pathogen Clostridioides difficile

Ramos-Silva, P.; Serrano, M.; Henriques, A. O.

10.1101/473793 — evolutionary biology — Posted on 2019-03-11

2298 Real-time contextual feedback for close-loop control of navigation

Lim, J.; Celikel, T.

10.1101/473108 — neuroscience — Posted on 2019-03-11

2299 Cerebellar contribution to preparatory activity in motor neocortex

Chabrol, F. P.; Blot, A.; Mrsic-Flogel, T. D.

10.1101/335703 — neuroscience — Posted on 2019-03-11

2300 Sen1 is required for RNA Polymerase III transcription termination in an R-loop independent manner.

Rivosecchi, J.; Larochelle, M.; Teste, C.; Grenier, F.; Malapert, A.; Ricci, E. P.; Bernard, P.; Bachand, F.; Vanoosthuyse, V.

10.1101/571737 — molecular biology — Posted on 2019-03-11

2301 A pressure sensing protein kinase

Akella, R.; Sekulski, K.; Pleinis, J. M.; Liwocha, J.; Jiou, J.; He, H.; Humphreys, J. M.; Schellinger, J. N.; Hu, J.; Cobb, M. H.; Joachimiak, L.; Rodan, A. R.; Goldsmith, E. J.

10.1101/435008 — biophysics — Posted on 2019-03-11

2302 Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders

10.1101/573279 — neuroscience — Posted on 2019-03-11

2303 Evaluation of extraction solvents for untargeted metabolomics analysis of enrichment reactor cultures performing enhanced biological phosphorus removal (EBPR)

Saw, N. M. M. T.; Suwanchaikasem, P.; Zuniga-Montanez, R. E.; Qiu, G.; Wuertz, S.; Williams, R. B.

10.1101/573535 — systems biology — Posted on 2019-03-11

2304 Intracranial functional haemodynamic relationships in patients with cerebral small vessel disease

Blair, G. W.; Thrippleton, M. J.; Shi, Y.; Hamilton, I.; Stringer, M.; Chappell, F. M.; Dickie, D. A.; Andrews, P. J.; Marshall, I.; Doubal, F. N.; Wardlaw, J. M.

10.1101/572818 — neuroscience — Posted on 2019-03-11

2305 Modularity in the microcircuitry of the mouse inferior colliculus yields dual processing streams for auditory and multisensory information

Lesicko, A. M. H.; Llano, D. A.

10.1101/572776 — neuroscience — Posted on 2019-03-11

2306 Toxoplasma controls host cyclin E expression through the use of a novel MYR1-dependent effector protein, HCE1

Panas, M. W.; Naor, A.; Cygan, A.; Boothroyd, J.

10.1101/573618 — microbiology — Posted on 2019-03-11

2307 Evolutionary patterns of the chimerical retrogenes in Oryza

Zhou, Y.; Song, H.; Xiao, J.; Zhang, Q.; Long, M.; Zhang, C.

10.1101/573501 — evolutionary biology — Posted on 2019-03-11

2308 Spreading of molecular mechanical perturbations on linear filaments

Balassy, Z.; Lauzon, A.-M.; Hilbert, L.

10.1101/573261 — biophysics — Posted on 2019-03-11

2309 Deriving Accurate Lipid Classification based on Molecular Formula

Mitchell, J. M.; Moseley, H. N. B.

10.1101/572883 — systems biology — Posted on 2019-03-11

2310 Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

Sanderson, L.; da Silva, M.; Sekhar, G. N.; Brown, R. C.; Burrell-Saward, H.; Fidanboylu, M.; Valero, M.; Dreiss, C. A.; Lorenz, C.; Christie, M.; Persaud, S.; Yardley, V.; Croft, S. L.; Thomas, S. A.

10.1101/573329 — pharmacology and toxicology — Posted on 2019-03-11

2311 A response to Zhang et al. (2018), \"Can Mouse-tracking Reveal Attribute Processing Speeds in Dietary Self-control? Commentary on Sullivan et al. (2015) and Lim et al. (2018)\"

Sullivan, N. J.; Hutcherson, C.; Harris, A. M.; Rangel, A.

10.1101/572974 — neuroscience — Posted on 2019-03-11

2312 Numerical simulations of different models describing cerebrospinal fluid dynamics

Romagnoli, L.

10.1101/573345 — neuroscience — Posted on 2019-03-11

2313 COI metabarcoding primer choice affects richness and recovery of indicator taxa in freshwater systems

Hajibabaei, M.; Porter, T. M.; Wright, M.; Rudar, J.

10.1101/572628 — genomics — Posted on 2019-03-11

2314 The importance of being cross-linked for the bacterial cell wall

Rani, G.; Patri, I.

10.1101/573113 — biophysics — Posted on 2019-03-11

2315 Intense Pulsed Electric Fields Denature Urease Protein

Urabe, G.; Katagiri, T.; Katsuki, S.

10.1101/572784 — biophysics — Posted on 2019-03-11

2316 Identification of DNA motifs that regulate DNA methylation

Wang, M.; Zhang, K.; Ngo, V.; Liu, C.; Fan, S.; Whitaker, J. W.; Chen, Y.; Ai, R.; Chen, Z.; Wang, J.; Zheng, L.; Wang, W.

10.1101/573352 — bioinformatics — Posted on 2019-03-11

2317 USVSEG: A robust segmentation of rodents’ ultrasonic vocalization

Tachibana, R. O.; Kanno, K.; Okabe, S.; Kobayasi, K. I.; Okanoya, K.

10.1101/572743 — animal behavior and cognition — Posted on 2019-03-11

2318 Visual awareness judgments are sensitive to the outcome of performance monitoring

Siedlecka, M.; Wereszczynski, M.; Paulewicz, B.; Wierzchon, M.

10.1101/572503 — animal behavior and cognition — Posted on 2019-03-11

2319 Regulation of cerebrospinal fluid and brain tissue sodium levels by choroid plexus and brain capillary endothelial cell Na+, K+-ATPases during migraine

Ghaffari, H.; Grant, S. C.; Petzold, L. R.; Harrington, M. G.

10.1101/572727 — systems biology — Posted on 2019-03-11

2320 Synergetic effect of non-complementary 5’ AT-rich sequences on the development of a multiplex TaqMan real-time PCR for specific and robust detection of Clavibacter michiganensis and C. michiganensis subsp. nebraskensis

Larrea-Sarmiento, A.; Alvarez, A. M.; Stack, J. P.; Arif, M.

10.1101/566281 — plant biology — Posted on 2019-03-11

2321 A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors

Lapin, D.; Kovacova, V.; Sun, X.; Dongus, J. A.; Bhandari, D. D.; von Born, P.; Bautor, J.; Guarneri, N.; Stuttmann, J.; Beyer, A.; Parker, J. E.

10.1101/572826 — plant biology — Posted on 2019-03-11

2322 Weed regulation by crop and grassland competition: critical biomass level and persistence rate

Schuster, M. Z.; Gastal, F.; Doisy, D.; Charrier, X.; de Moraes, A.; Mediene, S.; Barbu, C. M.

10.1101/572701 — plant biology — Posted on 2019-03-11

2323 Convergent gene loss in aquatic plants predicts new components of plant immunity and drought response

Baggs, E. L.; Thanki, A. S.; O'Grady, R.; Schudoma, C.; Haerty, W.; Krasileva, K. V.

10.1101/572560 — plant biology — Posted on 2019-03-11

2324 Affordable and robust phenotyping framework to analyse root system architecture of soil-grown plants

Bontpart, T.; Concha, C.; Giuffrida, M. V.; Robertson, I.; Admkie, K.; Abdi, T. D.; Wordofa, N. G.; Tesfaye, K.; Teklu, T. H.; Woldemedhin, A. F.; Fetene, M.; Tsaftaris, S.; Doerner, P.

10.1101/573139 — plant biology — Posted on 2019-03-11

2325 Comprehensive Classification of the RNaseH-like domain-containing Proteins in Plants

Li, S.; Liu, K.; Sun, Q.

10.1101/572842 — plant biology — Posted on 2019-03-11

2326 Biomarkers for capturing disease pathology as molecular process hyperstructure

Lukas, A.; Heinzel, A.; Mayer, B.

10.1101/573402 — pathology — Posted on 2019-03-11

2327 Cortical surface architecture endophenotype and correlates of clinical diagnosis of autism spectrum disorder

Yamagata, B.; Itahashi, T.; Fujino, J.; Ohta, H.; Takashio, O.; Nakamura, M.; Kato, N.; Mimura, M.; Hashimoto, R.-i.; Aoki, Y.

10.1101/573527 — neuroscience — Posted on 2019-03-11

2328 Neural basis of approximate number system develops independent of visual experience

Kanjlia, S.; Feigenson, L.; Bedny, M.

10.1101/573436 — neuroscience — Posted on 2019-03-11

2329 Neuropeptide B mediates female sexual receptivity in medaka fish, acting in a female-specific but reversible manner

Hiraki-Kajiyama, T.; Yamashita, J.; Yokoyama, K.; Hosono, K.; Kawabata-Sakata, Y.; Kikuchi, Y.; Miyazoe, D.; Ansai, S.; Kinoshita, M.; Nagahama, Y.; Okubo, K.

10.1101/573212 — neuroscience — Posted on 2019-03-11

2330 Quantitative Analysis of Trans-synaptic Protein Alignment

Chen, J.-H.; Blanpied, T. A.; Tang, A.-H.

10.1101/573063 — neuroscience — Posted on 2019-03-11

2331 Massively Parallel Microwire Arrays Integrated with CMOS chips for Neural Recording

Obaid, A. M.; Hanna, M.-E. S.; Wu, Y.-W.; Kollo, M.; Racz, R. R.; Angle, M. R.; Muller, J.; Brackbill, N.; Wray, W.; Franke, F.; Chichilnisky, E. J.; Hierlemann, A.; Ding, J. B.; Schaefer, A. T.; Melosh, N. A.

10.1101/573295 — neuroscience — Posted on 2019-03-11

2332 Send-receive communication asymmetry in brain networks: Inferring directionality of neural signalling from undirected structural connectomes

Seguin, C.; Razi, A.; Zalesky, A.

10.1101/573071 — neuroscience — Posted on 2019-03-11

2333 Effects of a rifampicin pre-treatment on linezolid pharmacokinetics

Oakazaki, F.; Tsuji, Y.; Seto, Y.; Ogami, C.; Yamamoto, Y.; To, H.

10.1101/572610 — molecular biology — Posted on 2019-03-11

2334 Genome-wide sequencing uncovers cryptic diversity and mito-nuclear discordance in the Octopus vulgaris species complex

Amor, M. D.; Doyle, S. R.; Norman, M. D.; Roura, A.; Hall, N. E.; Robinson, A. J.; Leite, T. S.; Strugnell, J. M.

10.1101/573493 — molecular biology — Posted on 2019-03-11

2335 Clades of huge phage from across Earth’s ecosystems

Al-Shayeb, B.; Sachdeva, R.; Chen, L.-X.; Ward, F.; Munk, P.; Devoto, A.; Castelle, C. J.; Olm, M. R.; Bouma-Gregson, K.; Amano, Y.; He, C.; Meheust, R.; Brooks, B.; Thomas, A.; Lavy, A.; Matheus-Carnevali, P.; Sun, C.; Goltsman, D.; Borton, M. A.; Nelson, T. C.; Kantor, R.; Jaffe, A. L.; Keren, R.; Farag, I. F.; Lei, S.; Finstad, K.; Amundson, R.; Anantharaman, K.; Zhou, J.; Probst, A. J.; Power, M. E.; Tringe, S. G.; Li, W.-J.; Wrighton, K.; Harrison, S.; Morowitz, M.; Relman, D. A.; Doudna, J. A.; Lehours, A.-C.; Warren, L.; Cate, J. H.; Santini, J. M.; Banfield, J. F.

10.1101/572362 — microbiology — Posted on 2019-03-11

2336 CUX1 and IκBζ mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts

Slowikowski, K.; Nguyen, H. N.; Noss, E. H.; Simmons, D. P.; Mizoguchi, F.; Watts, G. F.; Gurish, M. F.; Brenner, M. B.; Raychaudhuri, S.

10.1101/571315 — immunology — Posted on 2019-03-11

2337 Optimized Mucosal MVA Prime/ Soluble gp120 Boost Vaccination Regimen Induces Similar Antibody Responses as an Intramuscular Regimen

Jones, D. I.; Pollara, J. J.; Johnson-Weaver, B. T.; LaBranchi, C. C.; Montifiori, D. C.; Pickup, D. J.; Permar, S. R.; Abraham, S. N.; Maddaloni, M.; Pascual, D. W.; Staats, H. F.

10.1101/573394 — immunology — Posted on 2019-03-11

2338 Secondary ossification centers evolved to make endochondral bone growth possible under the weight-bearing demands of a terrestrial environment

Xie, M.; Goldin, P.; Herdina, A. N.; Estefa, J.; Medvedeva, E.; Li, L.; Newton, P.; Kotova, S.; Shavkuta, B.; Saxena, A.; Shumate, L.; Metscher, B.; Groschmidt, K.; Nishimori, S.; Akovantseva, A.; Arregui, I. L.; Tafforeau, P.; Fried, K.; Carlstrom, M.; Simon, A.; Gasser, C.; Kronenberg, H.; Bastepe, M.; Cooper, K.; Timashev, P.; Sanchez, S.; Adameyko, I.; Eriksson, A.; Chagin, A. S.

10.1101/571612 — evolutionary biology — Posted on 2019-03-11

2339 Universal trends of post-duplication evolution revealed by the genomes of 13 Paramecium species sharing an ancestral whole-genome duplication.

Gout, J.-F.; Johri, P.; Arnaiz, O.; Doak, T. G.; Bhullar, S.; Couloux, A.; Guerin, F.; Malinsky, S.; Sperling, L.; Labadie, K.; Meyer, E.; Duharcourt, S.; Lynch, M.

10.1101/573576 — evolutionary biology — Posted on 2019-03-11

2340 Positive genetic associations among fitness traits support evolvability of a reef-building coral under multiple stressors

Wright, R. M.; Mera, H.; Kenkel, C. D.; Nayfa, M.; Bay, L. K.; Matz, M. V.

10.1101/572321 — evolutionary biology — Posted on 2019-03-11

2341 Symbiont community diversity is more constrained in holobionts that tolerate diverse stressors

Howe-Kerr, L.; Bachelot, B.; Wright, R. M.; Kenkel, C. D.; Bay, L. K.; Correa, A. M. S.

10.1101/572479 — ecology — Posted on 2019-03-11

2342 An experimental manipulation of species’ phenologies overturns competitive hierarchies

Blackford, C.; Germain, R. M.; Gilbert, B.

10.1101/573204 — ecology — Posted on 2019-03-11

2343 Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters

Darbellay, F.; Bochaton, C.; Lopez-Delisle, L.; Mascrez, B.; Tschopp, P.; Delpretti, S.; Zakany, J.; Duboule, D.

10.1101/572875 — developmental biology — Posted on 2019-03-11

2344 The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection

Moskovskich, A.; Goldmann, U.; Kartnig, F.; Lindinger, S.; Konecka, J.; Fiume, G.; Girardi, E.; Superti-Furga, G.

10.1101/573253 — cell biology — Posted on 2019-03-11

2345 High-speed multifocal plane fluorescence microscopy for three-dimensional visualisation of beating flagella

Wheeler, R.

10.1101/573485 — cell biology — Posted on 2019-03-11

2346 METABOLIC DIVERSITY IN HUMAN NON-SMALL CELL LUNG CANCER CELLS

CHEN, P.-H.; Cai, L.; Yang, C.; Kim, J.; Faubert, B.; Boroughs, L.; Ko, B.; Sudderth, J.; McMillan, E. A.; Girard, L.; Peyton, M.; Huffman, K.; Shields, M. D.; Shames, D.; Kim, H. S.; Timmons, B.; Sekine, I.; Britt, R.; Weber, S.; Byers, L. A.; Heymach, J. V.; White, M. A.; Minna, J.; Xiao, G.; DeBerardinis, R. J.

10.1101/561688 — cancer biology — Posted on 2019-03-11

2347 The Mut+ strain of Komagataella phaffii (Pichia pastoris) expresses PAOX1 5 and 10 times faster than Muts and Mut- strains: Evidence that formaldehyde or/and formate are true inducers of AOX.

Singh, A.; Narang, A.

10.1101/573519 — bioengineering — Posted on 2019-03-11

2348 The ER membrane protein complex is important for the biogenesis of flavivirus polyproteins

Ngo, A. M.; Shurtleff, M. J.; Popova, K. D.; Kulsuptrakul, J.; Weissman, J. S.; Puschnik, A. S.

10.1101/572602 — microbiology — Posted on 2019-03-11

2349 Vertical niche definition of test-bearing protists (Rhizaria) into the twilight zone revealed by in situ imaging

Biard, T.; Ohman, M.

10.1101/573410 — ecology — Posted on 2019-03-11

2350 Deregulation of TGF-β1 signaling induces glycolysis by chromatin remodeling in pathogenic TH17 cells

Yu, X.; Wang, L.; Han, Z.; Yao, C.; Qiu, R.; Cui, Y.; Dai, D.; Jin, W.; Shen, N.

10.1101/218545 — immunology — Posted on 2019-03-10

2351 Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Wang, Q.; Pierce-Hoffman, E.; Cummings, B. B.; Karczewski, K. J.; Alfoldi, J.; Francioli, L. C.; Gauthier, L. D.; Hill, A. J.; O'Donnell-Luria, A. H.; Genome Aggregation Database Production Team, ; Genome Aggregation Database Consortium, ; MacArthur, D. G.

10.1101/573378 — genomics — Posted on 2019-03-10

2352 Reliable analysis of clinical tumor-only whole exome sequencing data

Oh, S.; Geistlinger, L.; Ramos, M.; Morgan, M.; Waldron, L.; Riester, M.

10.1101/552711 — bioinformatics — Posted on 2019-03-10

2353 Genotype-free demultiplexing of pooled single-cell RNA-seq

Xu, J.; Falconer, C.; Coin, L.

10.1101/570614 — bioinformatics — Posted on 2019-03-10

2354 Auxin-sensitive Aux/IAA proteins mediate drought tolerance in Arabidopsis by regulating glucosinolate levels

Estelle, M.; Salehin, M.; Li, B.; Tang, M.; Katz, E.; Song, L.; Ecker, J.; Kliebenstein, D.

10.1101/572305 — plant biology — Posted on 2019-03-10

2355 Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Wang, Q.; Pierce-Hoffman, E.; Cummings, B. B.; Karczewski, K. J.; Alfoldi, J.; Francioli, L. C.; Gauthier, L. D.; Hill, A. J.; O'Donnell-Luria, A. H.; Genome Aggregation Database (gnomAD) Production Te, ; Genome Aggregation Database (gnomAD) Consortium, ; MacArthur, D. G.

10.1101/573378 — genomics — Posted on 2019-03-10

2356 Prevalence and risk factors profile of seropositive Toxoplasmosis gondii infection among apparently immunocompetent Sudanese women

Mustafa, M.; Fathy, F.; Mirghani, A.; Mohamed, M. A.; Muneer, M. S.; Ahmed, A. E.; Ali, M. S.; Omer, R. A.; Siddig, E. E.; Mohamed, N. S.; Abd Elkareem, A. M.

10.1101/572800 — microbiology — Posted on 2019-03-10

2357 Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria

10.1101/572354 — genomics — Posted on 2019-03-10

2358 The life of P.I. - Transitions to Independence in Academia

Acton, S. E.; Bell, A.; Toseland, C.; Twelvetrees, A.

10.1101/571935 — scientific communication and education — Posted on 2019-03-10

2359 From prior information to saccade selection: evolution of frontal eye field activity during natural scene search

Glaser, J. I.; Wood, D. K.; Lawlor, P. N.; Segraves, M. A.; Kording, K. P.

10.1101/251835 — neuroscience — Posted on 2019-03-10

2360 The optimal odor-receptor interaction network is sparse in olfactory systems: Compressed sensing by nonlinear neurons with a finite dynamic range

Qin, S.; Li, Q.; Tang, C.; Tu, Y.

10.1101/464875 — neuroscience — Posted on 2019-03-10

2361 The summary diagram of discovered host immunological pathways against different pathogens and its relation to hypersensitivities

Hu, W.

10.1101/006965 — immunology — Posted on 2019-03-10

2362 Molecular properties and evolutionary origins of a parvovirus-derived myosin fusion gene in guinea pigs

Valencia-Herrera, I.; Cena-Ahumada, E.; Faunes, F.; Ibarra-Karmy, R.; Gifford, R. J.; Arriagada, G.

10.1101/572735 — evolutionary biology — Posted on 2019-03-10

2363 Bacteria are required for regeneration of the Xenopus tadpole tail

Bishop, T. F.; Beck, C. W.

10.1101/319939 — developmental biology — Posted on 2019-03-10

2364 Weak Membrane Interactions Allow Rheb to Activate mTORC1 Signaling Without Major Lysosome Enrichment

Angarola, B.; Ferguson, S. M.

10.1101/513473 — cell biology — Posted on 2019-03-10

2365 BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells

Janssen, S. M.; Moscona, R.; Elchebly, M.; Papadakis, A. I.; Redpath, M.; Wang, H.; Rubin, E.; van Kempen, L. C.; Spatz, A.

10.1101/560474 — cancer biology — Posted on 2019-03-10

2366 Intrinsically disordered nuclear pore proteins show ideal-polymer morphologies and dynamics

Davis, L. K.; Ford, I. J.; Saric, A.; Hoogenboom, B.

10.1101/571687 — biophysics — Posted on 2019-03-10

2367 Designing a novel multi-epitope T vaccine for \"targeting protein for Xklp-2\" (TPX2) in hepatocellular carcinoma based on immunoinformatics approach

Ghahremanifard, P.; Afzali, F.; Rostami, A.; Nayeri, Z.; Bambai, B.; Minuchehr, Z.

10.1101/570952 — bioinformatics — Posted on 2019-03-10

2368 Looking for Therapeutic Antibodies in Next Generation Sequencing Repositories

Krawczyk, K.; Kovaltsuk, A.; Raybould, M.; Deane, C.

10.1101/572958 — bioinformatics — Posted on 2019-03-10

2369 Landscape and dynamics of the transcriptional regulatory network during natural killer cell differentiation

Li, K.; Wu, Y.; Li, Y.; Yu, Q.; Tian, Z.; Wei, H.; Qu, K.

10.1101/572768 — bioinformatics — Posted on 2019-03-10

2370 Temperature drives the evolution and global distribution of avian eggshell colour

Wisocki, P. A.; Kennelly, P.; Rojas Rivera, I.; Cassey, P.; Hanley, D.

10.1101/559435 — ecology — Posted on 2019-03-10

2371 How many cubs can a mum nurse? Maternal age and size influence litter size in polar bears

Folio, D. M.; Aars, J.; Gimenez, O.; Derocher, A. E.; Wiig, O.; Cubaynes, S.

10.1101/532945 — ecology — Posted on 2019-03-10

2372 Recognition Genes Which Are Relative With Cancer By Deep Learning Algorithm

Zou, B.

10.1101/571851 — bioinformatics — Posted on 2019-03-09

2373 Temporal variation of fatty acid composition and pesticides in honeybees Apis mellifera and beebread

Gooley, Z. C.; Gooley, A.

10.1101/572149 — zoology — Posted on 2019-03-09

2374 Intercellular positive-feedback loops promote the evolutionary stability of microbial cooperative behaviors

Ben-Zion, I.; Eldar, A.

10.1101/571562 — systems biology — Posted on 2019-03-09

2375 Cytokinin functions as an asymmetric and anti-gravitropic signal in lateral roots

Waidmann, S.; Ruiz Rosquete, M.; Scholler, M.; Lindner, H.; LaRue, T.; Sarkel, E.; Petrik, I.; Dunser, K.; Martopawiro, S.; Sasidharan, R.; Novak, O.; Wabnik, K.; Dinneny, J. R.; Kleine-Vehn, J.

10.1101/572941 — plant biology — Posted on 2019-03-09

2376 3D spatially-resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

Segovia-Miranda, F.; Morales-Navarrete, H.; Kucken, M.; Moser, V.; Seifert, S.; Repnik, U.; Rost, F.; Hendriks, A.; Hinz, S.; Rocken, C.; Luthjohann, D.; Kalaidzidis, Y.; Schafmayer, C.; Brusch, L.; Hampe, J.; Zerial, M.

10.1101/572073 — pathology — Posted on 2019-03-09

2377 Cellular and network mechanisms may generate sparse coding of sequential object encounters in hippocampal-like circuits

Trinh, A.-T.; Clarke, S. E.; Harvey-Girard, E.; Maler, L.

10.1101/571414 — neuroscience — Posted on 2019-03-09

2378 Histological validation of per-bundle water diffusion metrics within a region of fiber crossing following axonal degeneration

Rojas-Vite, G.; Coronado-Leija, R.; Narvaez-Delgado, O.; Ramirez-Manzanares, A.; Marroquin, J.-L.; Noguez-Imm, R.; Aranda, M. L.; Scherrer, B.; Larriva-Sahd, J.; Concha, L.

10.1101/571539 — neuroscience — Posted on 2019-03-09

2379 Tactile sensory channels over-ruled by frequency decoding system that utilizes spike pattern regardless of receptor type

Birznieks, I.; McIntyre, S.; Nilsson, H. M.; Nagi, S. S.; Macefield, V. G.; Mahns, D. A.; Vickery, R. M.

10.1101/570929 — neuroscience — Posted on 2019-03-09

2380 Event segmentation reveals working memory forgetting rate

Jafarpour, A.; Buffalo, E.; Knight, R.; Collins, A.

10.1101/571380 — neuroscience — Posted on 2019-03-09

2381 Behavioural and neural limits in competitive decision making: The roles of outcome, opponency and observation

Dyson, B.; Steward, B. A.; Meneghetti, T.; Forder, L.

10.1101/571257 — neuroscience — Posted on 2019-03-09

2382 Analytic Model of fMRI BOLD Signals for Separable Metrics of Neural and Metabolic Activity

Schaper, C.

10.1101/573006 — neuroscience — Posted on 2019-03-09

2383 SPiQE: an automated analytical tool for detecting and characterising fasciculations in amyotrophic lateral sclerosis

Bashford, J.; Wickham, A.; Iniesta, R.; Drakakis, E.; Boutelle, M.; Mills, K.; Shaw, C.

10.1101/571893 — neuroscience — Posted on 2019-03-09

2384 Targeting MOG to skin macrophages prevents EAE in macaques through TGFβ-induced peripheral tolerance

Fovet, C.-M.; Stimmer, L.; Contreras, V.; Horellou, P.; Hubert, A.; Seddiki, N.; Chapon, C.; Tricot, S.; Leroy, C.; Flament, J.; Massonneau, J.; Tchitchek, N.; 't Hart, B.; Zurawski, S.; Klucar, P.; Deiva, K.; Zurawski, G.; Oh, S.; Le Grand, R.; Serguera, C.

10.1101/571828 — immunology — Posted on 2019-03-09

2385 Lactate potentiates differentiation and expansion of cytotoxic T cells

Rundqvist, H.; Velica, P.; Barbieri, L.; Gameiro, P.; Cunha, P.; Gojkovic, M.; Mijwel, S.; Ahlstedt, E.; Foskolou, I. P.; Ruiz-Perez, M.; Arsenian-Henriksson, M.; Ule, J.; Ostman, A.; Johnson, R.

10.1101/571745 — immunology — Posted on 2019-03-09

2386 Fine mapping using whole-genome sequencing confirms anti Mullerian hormone as a major gene for sex determination in farmed Nile tilapia (Oreochromis niloticus L.)

Caceres, G.; Lopez, M. E.; Cadiz, M. I.; Yoshida, G.; Jedlicki, A.; Palma-Vejares, R.; Travisany, D.; Diaz-Dominguez, D.; Maass, A.; Lhorente, J.-P.; Soto, J.; Salas, D.; Yanez, J. M.

10.1101/573014 — genomics — Posted on 2019-03-09

2387 CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests its role in anxiety and male alcohol intake.

McEwan, A. R.; Hay, E.; Davidson, C.; Turnbull, Y.; Marini, P.; Wilson, D.; McIntosh, A.; Adams, M. J.; Murgatroyd, C.; Barrett, P.; Delibegovic, M.; Clarke, T.-K.; MacKenzie, A.

10.1101/572065 — genetics — Posted on 2019-03-09

2388 Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen Pseudomonas aeruginosa

Barbosa, C.; Roemhild, R.; Rosenstiel, P.; Schulenburg, H.

10.1101/570663 — evolutionary biology — Posted on 2019-03-09

2389 Evolution, not transgenerational plasticity, explains the divergence of acorn ant thermal tolerance across an urban-rural temperature cline

Martin, R. A.; Chick, L. D.; Yilmaz, A. R.; Diamond, S. E.

10.1101/571521 — evolutionary biology — Posted on 2019-03-09

2390 Soil protist diversity in the Swiss western Alps is better predicted by topo-climatic than by edaphic variables

Seppey, C. V. W.; Broennimann, O.; Buri, A.; Yashiro, E.; Pinto-Figueroa, E.; Singer, D.; Blandenier, Q.; Mitchell, E. A. D.; Niculita Hirzel, H.; Guisan, A.; Lara, E.

10.1101/571760 — ecology — Posted on 2019-03-09

2391 Survival of prey growing through gape-limited predators

Anderson, J. J.

10.1101/571356 — ecology — Posted on 2019-03-09

2392 Looking for Therapeutic Antibodies in Next Generation Sequencing Repositories

Krawczyk, K.; Kovaltsuk, A.; Raybould, M.; Deane, C. M.

10.1101/572958 — bioinformatics — Posted on 2019-03-09

2393 A Bayesian framework for inferring the influence of sequence context on single base modifications

Ling, G.; Miller, D.; Nielsen, R.; Stern, A.

10.1101/571646 — bioinformatics — Posted on 2019-03-09

2394 SF3B1ness score: screening SF3B1 mutation status from over 60,000 transcriptomes based on a machine learning approach

Shiraishi, Y.; Chiba, K.; Okada, A.

10.1101/572834 — bioinformatics — Posted on 2019-03-09

2395 ExpansionHunter: A sequence-graph based tool to analyze variation in short tandem repeat regions

Dolzhenko, E.; Deshpande, V.; Schlesinger, F.; Krusche, P.; Petrovski, R.; Chen, S.; Emig-Agius, D.; Gross, A.; Narzisi, G.; Bowman, B.; Scheffler, K.; van Vugt, J. J. F. A.; French, C.; Sanchis-Juan, A.; Ibanez, K.; Tucci, A.; Lajoie, B.; Veldink, J. H.; Raymond, L.; Taft, R. J.; Bentley, D. R.; Eberle, M. A.

10.1101/572545 — bioinformatics — Posted on 2019-03-09

2396 Revealing new therapeutic opportunities through drug target prediction via class imbalance-tolerant machine learning

Liang, S.; Yu, H.

10.1101/572420 — bioinformatics — Posted on 2019-03-09

2397 Nicotinamide Deficiency In Primary Open-Angle Glaucoma

10.1101/571638 — biochemistry — Posted on 2019-03-09

2398 Transcriptional signatures of invasiveness in Meloidogyne incognita populations from sub-Saharan Africa

Cox, D. E.; Reilly, B.; Warnock, N. D.; Dyer, S.; Sturrock, M.; Cortada, L.; Coyne, D.; Maule, A. G.; Dalzell, J. J.

10.1101/570770 — animal behavior and cognition — Posted on 2019-03-09

2399 Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata via accelerating CaCO3 nucleation

Huang, J.; Liu, Y.; Jiang, T.; Dong, W.; Zheng, G.; Xie, L.; Zhang, R.

10.1101/572024 — zoology — Posted on 2019-03-09

2400 A distinct pool of Nav1.5 channels at the lateral membrane of murine ventricular cardiomyocytes

Rougier, J.-S.; Essers, M. C.; Gillet, L.; Guichard, S.; Sonntag, S.; Shmerling, D.; Abriel, H.

10.1101/572180 — physiology — Posted on 2019-03-09

2401 Time-course of population activity along the dorsoventral extent of the superior colliculus during delayed saccade tasks

Massot, C.; Jagadisan, U. K.; Gandhi, N. J.

10.1101/571307 — neuroscience — Posted on 2019-03-09

2402 Corticotropin-Releasing Hormone Signaling in the Oval Bed Nucleus of the Stria Terminalis Mediates Chronic Stress-Induced Negative Valence Behaviors Associated with Anxiety

Hu, P.; Maita, I.; Kwok, C.; Gu, E.; Gergues, M.; Liu, J.; Pang, Z.; Swaab, D. F.; Lucassen, P. J.; Roepke, T. A.; Samuels, B. A.

10.1101/572966 — neuroscience — Posted on 2019-03-09

2403 Resting-state functional connectivity modulates the BOLD activation induced by nucleus accumbens stimulation in the swine brain

Cho, S.; Hachmann, J. T.; Balzekas, I.; In, M.-H.; Andres-Beck, L. G.; Lee, K. H.; Min, H.-K.; Jo, H. J.

10.1101/571513 — neuroscience — Posted on 2019-03-09

2404 Large-scale chemical-genetics of the human gut bacterium Bacteroides thetaiotaomicron

Liu, H.; Price, M. N.; Carlson, H. K.; Chen, Y.; Ray, J.; Shiver, A. L.; Petzold, C. J.; Huang, K. C.; Arkin, A. P.; Deutschbauer, A.

10.1101/573055 — microbiology — Posted on 2019-03-09

2405 Genome-wide association study and low-cost genomic predictions for growth and fillet yield in Nile tilapia (Oreochromis niloticus)

Yoshida, G.; Lhorente, J. P.; Correa, K.; Soto, J.; Salas, D.; Yanez, J.

10.1101/573022 — genomics — Posted on 2019-03-09

2406 The optimal discovery procedure for significance analysis of general gene expression studies

Bass, A. J.; Storey, J. D.

10.1101/571992 — bioinformatics — Posted on 2019-03-09

2407 A low-cost, open-source framework for tracking and behavioural analysis of animals in aquatic ecosystems

Francisco, F. A.; Nuehrenberg, P.; Jordan, A.

10.1101/571232 — animal behavior and cognition — Posted on 2019-03-09

2408 Recent and rapid colonization of the Lesser Sundas Archipelago from adjacent Sundaland by seven amphibian and reptile species

Reilly, S. B.; Stubbs, A. L.; Karin, B. R.; Arida, E.; Iskandar, D. T.; McGuire, J. A.

10.1101/571471 — zoology — Posted on 2019-03-09

2409 Active Efficient Coding Explains the Development of Binocular Vision and its Failure in Amblyopia

Eckmann, S.; Klimmasch, L.; Shi, B. E.; Triesch, J.

10.1101/571802 — neuroscience — Posted on 2019-03-09

2410 Automated and Manual Quantification of Tumour Cellularity in Digital Slides for Tumour Burden Assessment

Akbar, S.; Peikari, M.; Salama, S.; Panah, A. Y.; Nofech-Momes, S.; Martel, A. L.

10.1101/571190 — pathology — Posted on 2019-03-09

2411 Aberrant Population Receptive Fields in Human Albinism

Duwell, E. J.; Woertz, E. N.; Mathis, J.; Carroll, J.; DeYoe, E. A.

10.1101/572289 — neuroscience — Posted on 2019-03-09

2412 Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development

Baumgarten, S.; Bryant, J. M.; Sinha, A.; Reyser, T.; Preiser, P. R.; Dedon, P. C.; Scherf, A.

10.1101/572891 — molecular biology — Posted on 2019-03-09

2413 Thermal preferences drive behavioural responses but not biomass responses of predatory fishes to lake morphometry

Bartley, T. J.; Guzzo, M. M.; Cazelles, K.; Verville, A.; McMeans, B. C.; McCann, K. S.

10.1101/572925 — ecology — Posted on 2019-03-09

2414 Determining the Minimal Background Area for Species Distribution Models: MinBAR Package

Rotllan-Puig, X.; Traveset, A.

10.1101/571182 — ecology — Posted on 2019-03-09

2415 Cascaded-CNN: Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps

Moritz, S.; Pfab, J.; Si, D.; Wu, T.; Hou, J.; Cheng, J.; Cao, R.; Wang, L.

10.1101/572990 — molecular biology — Posted on 2019-03-09

2416 Distinct Regulation of Bioenergetics and Translation by Gp I mGluRs and NMDARs

Ghosh Dastidar, S.; Chakraborty, S.; Chattarji, S.; Bhattacharya, A.; Muddashetty, R.

10.1101/552638 — neuroscience — Posted on 2019-03-09

2417 Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance in a model gut microbiota

Aranda-Diaz, A.; Obadia, B.; Thomsen, T.; Hallberg, Z. F.; Guvener, Z. T.; Huang, K. C.; Ludington, W. B.

10.1101/538132 — microbiology — Posted on 2019-03-09

2418 Machine learning in drug development

Sahli Costabal, F.; Seo, K.; Ashley, E.; Kuhl, E.

10.1101/545863 — biophysics — Posted on 2019-03-09

2419 Wolbachia pipientis occurs in Aedes aegypti populations in New Mexico and Florida, USA

Kulkarni, A.; Yu, W.; Jiang, J.; Sanchez, C.; Karna, A. K.; Martinez, K. J. L.; Hanley, K. A.; Buenemann, M.; Hansen, I. A.; Xue, R.-d.; Ettestad, P.; Melman, S.; Duguma, D.; Debboun, M.; Xu, J.

10.1101/455014 — ecology — Posted on 2019-03-09

2420 Jag1 coordinates release from multipotency with cell fate choice in the developing pancreas

Seymour, P. A.; Collin, C. A.; Jorgensen, M. C.; Imayoshi, I.; Honnens de Lichtenberg, K. H.; Kopan, R.; Kageyama, R.; Serup, P.

10.1101/336529 — developmental biology — Posted on 2019-03-09

2421 Identifying drug combinations of individual cancer patients by personalized drug controller method

Guo, W.; Zhang, S.-W.; Zeng, T.; Chen, L.

10.1101/571620 — systems biology — Posted on 2019-03-09

2422 Mammalian olfaction is a high temporal bandwidth sense

Erskine, A.; Ackels, T.; Dasgupta, D.; Fukunaga, I.; Schaefer, A. T.

10.1101/570689 — neuroscience — Posted on 2019-03-09

2423 The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs

Piskacek, M.; Havelka, M.; Jendruchova, K.; Knight, A.; Keegan, L. P.

10.1101/570598 — molecular biology — Posted on 2019-03-09

2424 A General Statistic to Test an Optimally WeightedCombination of Common and/or Rare Variants

Zhang, J.; WU, B.; Sha, Q.; zhang, s.; wang, x.

10.1101/572115 — genetics — Posted on 2019-03-09

2425 Designing a novel multi-epitope T vaccine for targeting protein for Xklp-2 (TPX2) in hepatocellular carcinoma based on immunoinformatics approach

Ghahremanifard, P.; Afzali, F.; Rostami, A.; Nayeri, Z.; Minuchehr, Z.

10.1101/570952 — bioinformatics — Posted on 2019-03-09

2426 Plant evolution further threatens declining pollinator populations

Weinbach, A.; Loeuille, N.; Rohr, R. P.

10.1101/570580 — ecology — Posted on 2019-03-09

2427 Chromosomes function as a barrier to mitotic spindle bipolarity in polyploid cells

Goupil, A.; Nano, M.; Letort, G.; Gogendeau, D.; Pennetier, C.; Basto, R.

10.1101/572099 — cell biology — Posted on 2019-03-09

2428 Bid as a novel interacting partner of IRE1 differentially regulating its RNAse activity

Bashir, S.; Fazili, K. M.

10.1101/572222 — cell biology — Posted on 2019-03-09

2429 Oncogenic signaling alters cell shape and mechanics to facilitate cell division under confinement.

Matthews, H. K.; Ganguli, S.; Plak, K.; Taubenberger, A. V.; Piel, M.; Guck, J.; Baum, B.

10.1101/571885 — cell biology — Posted on 2019-03-09

2430 Structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma

10.1101/572248 — cancer biology — Posted on 2019-03-09

2431 The orientation of a membrane probe from structural analysis by enhanced Raman scattering

Hughes, H. J.; Demers, S. M. E.; Zhang, A.; Hafner, J. H.

10.1101/572529 — biophysics — Posted on 2019-03-09

2432 Charting shared developmental trajectories of cortical thickness and structural connectivity in childhood and adolescence

Ball, G.; Beare, R.; Seal, M. L.

10.1101/572552 — neuroscience — Posted on 2019-03-09

2433 Genetic analysis of TP53 gene mutations in exon 4 and exon 8 among esophageal cancer patients in Sudan

Eltaher, S. M.; Idris, A. B.; H, M. A.; Mohamed Yousif, M. Y.; Mohamed, N. S.; Abdel Hamid, M. M.; Elsiddig, K. E.; Yousif, G. M.; Hassan, M. A.

10.1101/572214 — cancer biology — Posted on 2019-03-09

2434 Modulation of Rapid Visual Responses during Reaching by Multimodal Stimuli

Glover, I. S.; Baker, S. N.

10.1101/570796 — neuroscience — Posted on 2019-03-09

2435 Altered structural brain asymmetry in autism spectrum disorder: large-scale analysis via the ENIGMA Consortium

10.1101/570655 — neuroscience — Posted on 2019-03-09

2436 Resistance Rate Distribution of MDR-TB Among Pulmonary Tuberculosis Patients Attending Nnamdi Azikiwe University Teaching Hospital Nnewi and ST Patrick’S Hospital Mile 4 Abakiliki in Southeast Nigeria

Okoro, C. E.; Akujobi, C. N.; Udoh, I. P.; Ibhawaegbele, S. O.; Ezema, C. I.; Ezeugwu, U. A.; Dozie-Nwakile, O. C.; Okpe, A. C.

10.1101/570416 — microbiology — Posted on 2019-03-09

2437 Outbreak of murine infection with Clostridium difficile associated with the administration of a pre- and peri-natal methyl-donor diet

Mau, T.; Eckley, S. S.; Bergin, I. L.; Saund, K.; Villano, J. S.; Vendrov, K. C.; Snitkin, E. S.; Young, V. B.; Yung, R.

10.1101/565762 — epidemiology — Posted on 2019-03-09

2438 Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration

Wei, L.; Blader, P.; Roussigne, M.

10.1101/570820 — cell biology — Posted on 2019-03-09

2439 An atlas of anterior hox gene expression in the embryonic sea lamprey head: hox-code evolution in vertebrates

Parker, H. J.; Bronner, M. E.; Krumlauf, R.

10.1101/571448 — developmental biology — Posted on 2019-03-09

2440 The Neural Basis of Shared Preference Learning

Farmer, H.; Hamilton, A.; Hertz, U.

10.1101/570762 — neuroscience — Posted on 2019-03-09

2441 Conserving unprotected important coastal habitats in the Yellow Sea: shorebird occurrence, distribution and food resources at Lianyungang

Chan, Y.-C.; Peng, H.-B.; Han, Y.-X.; Chung, S. S.-W.; Li, J.; Zhang, L.; Piersma, T.

10.1101/570556 — ecology — Posted on 2019-03-09

2442 Comparison Between Normobaric Hypoxia Altitude Simulation Test and Altitude Hypoxia Predictive Equations in Cystic Fibrosis Patients

Costa, C.; Barros, A.; Rodrigues, J. V.; Staats, R.; Alves, M.; Cardim, P.; Lopes, C.; Barbara, C.; Moita, L.; Moreira, S.

10.1101/570754 — pathology — Posted on 2019-03-09

2443 In search of Universal Cortical Power Changes Linked to NMDA-Antagonist based Anesthetic Induced Reductions in Consciousness.

Pelentritou, A.; Kuhlmann, L.; Cormack, J.; Mcguigan, S.; Woods, W.; Muthukumaraswamy, S.; Liley, D.

10.1101/572636 — neuroscience — Posted on 2019-03-09

2444 Selective Liposomal Transport Through Blood Brain Barrier Disruption in Ischaemic Stroke Reveals Two Distinct Therapeutic Opportunities

Al-Ahmady, Z. S.; Jasim, D.; Ahmad, S.; Wong, R.; Haley, M.; Coutts, G.; Schiessl, I.; Allan, S. M.; Kostarelos, K.

10.1101/570234 — neuroscience — Posted on 2019-03-09

2445 Fear Learning Induces Long-Lasting Changes in Gene Expression and Pathway Specific Presynaptic Growth

Dillingham, B. C.; Cameron, P.; Pieraut, S.; Cardozo, L. M.; Yoo, E. J.; Maximov, A.; Stowers, L.; Mayford, M.

10.1101/571331 — neuroscience — Posted on 2019-03-09

2446 Modeling decision-making under uncertainty: a direct comparison study between human and mouse gambling data

Cabeza Alvarez, L.; Giustiniani, J.; Chabin, T.; Ramadan, B.; Joucla, C.; Nicolier, M.; Pazart, L.; Haffen, E.; Fellmann, D.; Gabriel, D.; Peterschmitt, Y.

10.1101/570499 — neuroscience — Posted on 2019-03-09

2447 The effect of diffusion on asymmetric spin echo based quantitative BOLD: An investigation of the origin of deoxygenated blood volume overestimation

Stone, A. J.; Holland, N. C.; Berman, A. J.; Blockley, N.

10.1101/570697 — neuroscience — Posted on 2019-03-09

2448 Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank

Van Hout, C. V.; Tachmazidou, I.; Backman, J. D.; Hoffman, J. X.; Yi, B.; Pandey, A.; Gonzaga-Jauregui, C.; Khalid, S.; Liu, D.; Banerjee, N.; Li, A. H.; O'Dushlaine, C.; Marcketta, A.; Staples, J.; Schumann, C.; Hawes, A.; Maxwell, E.; Barnard, L.; Lopez, A.; Penn, J.; Habegger, L.; Blumenfeld, A. L.; Yadav, A.; Praveen, K.; Jones, M.; Salerno, W. J.; Chung, W. K.; Surakka, I.; Willer, C. J.; Hveem, K.; Leader, J. B.; Carey, D. J.; Ledbetter, D. H.; Cardon, L.; Yancopoulos, G. D.; Economides, A.; Coppola, G.; Shuldiner, A. R.; Balasubramanian, S.; Cantor, M.; Nelson, M. R.; Whittaker, J. C.;

10.1101/572347 — genomics — Posted on 2019-03-09

2449 Transfer of Xanthomonas campestris pv. arecae, and Xanthomonas campestris pv. musacearum to Xanthomonas vasicola (Vauterin) as Xanthomonas vasicola pv. arecae comb. nov., and Xanthomonas vasicola pv. musacearum comb. nov. and description of Xanthomonas vasicola pv. vasculorum pv. nov.

Studholme, D. J.; Wicker, E.; Bogdanove, A.; Broders, K.; Dubrow, Z.; Grant, M.; Jones, J. B.; Karamura, G.; Lang, J.; Leach, J.; Abrare, S. M.; Mahuku, G.; Nakato, G. V.; Coutinho, T.; Smith, J.; Bull, C.

10.1101/571166 — microbiology — Posted on 2019-03-09

2450 Variation of immune cell responses in humans reveals sex-specific coordinated signaling across cell types

Fragiadakis, G. K.; Bjornson-Hooper, Z. B.; Madhireddy, D.; Sachs, K.; Spitzer, M. H.; Bendall, S. C.; Nolan, G. P.

10.1101/567784 — immunology — Posted on 2019-03-09

2451 Comparative analysis of EHR-based stroke phenotyping methods, their applications, and interpretation

Thangaraj, P. M.; Kummer, B.; Lorberbaum, T.; Elkind, M.; Tatonetti, N. P.

10.1101/565671 — bioinformatics — Posted on 2019-03-09

2452 The shape of gene expression distributions matter: how incorporating distribution shape improves the interpretation of cancer transcriptomic data

de Torrente, L.; Zimmerman, S.; Suzuki, M.; Christopeit, M.; Greally, J. M.; Mar, J.

10.1101/572693 — bioinformatics — Posted on 2019-03-09

2453 The Anaerobic Efflux Pump MdtEF-TolC Confers Resistance to Cationic Biocides

Novoa, D.; Conroy-Ben, O.

10.1101/570408 — microbiology — Posted on 2019-03-09

2454 Pulcherrimin formation controls growth arrest of the Bacillus subtilis biofilm

Arnaouteli, S.; Matoz Fernandez, D. A.; Porter, M.; Kalamara, M.; Abbott, J.; MacPhee, C.; Davidson, F.; Stanley-Wall, N.

10.1101/570630 — microbiology — Posted on 2019-03-09

2455 Genetic determinants in Salmonella enterica serotype Typhimurium required for overcoming stressors in the host environment

Mandal, R. K.; Jiang, T.; Kwon, Y. M.

10.1101/571273 — microbiology — Posted on 2019-03-09

2456 The type VII secretion system protects Staphylococcus aureus against antimicrobial host fatty acids

Kengmo Tchoupa, A.; Jones, R. A.; Kuroki, A.; Alam, M. T.; Perrier, S.; Chen, Y.; Unnikrishnan, M.

10.1101/572172 — microbiology — Posted on 2019-03-09

2457 The ER membrane protein complex is important for the biogenesis of flavivirus polyproteins

Ngo, A. M.; Shurtleff, M. J.; Popova, K. D.; Kulsuptrakul, J.; Weissman, J. S.; Puschnik, A. S.

10.1101/572602 — microbiology — Posted on 2019-03-09

2458 DNA damage-specific effects of Tel1/ATM and γH2A/γH2AX on checkpoint signaling in Saccharomyces cerevisiae

Siler, J.; Huo, N.; Liu, Z.; Qin, Y.; Bi, X.

10.1101/572271 — molecular biology — Posted on 2019-03-09

2459 Short translational ramp determines efficiency of protein synthesis

Verma, M.; Choi, J.; Cottrell, K. A.; Lavagnino, Z.; Thomas, E. N.; Pavlovic Djuranovic, S.; Szczesny, P.; Piston, D. W.; Zaher, H.; Puglisi, J. D.; Djuranovic, S.

10.1101/571059 — molecular biology — Posted on 2019-03-09

2460 Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics

Ersoy, S. C.; Abdelhady, W.; Li, L.; Chambers, H. F.; Xiong, Y. Q.; Bayer, A.

10.1101/570424 — microbiology — Posted on 2019-03-09

2461 Development, characterization and standardization of a nose-only inhalation exposure system for exposure of rabbits to small particle aerosols containing Francisella tularensis.

O'Malley, K. J.; Bowling, J. D.; Barry, E. M.; Hazlett, K. R. O.; Reed, D. S.

10.1101/570432 — microbiology — Posted on 2019-03-09

2462 The solution structure of Dead End bound to AU-rich RNA reveals an unprecedented mode of tandem RRM-RNA recognition required for mRNA repression

Duszczyk, M. M.; Wischnewski, H.; Kazeeva, T.; Loughlin, F. E.; von Schroetter, C.; Pradere, U.; Hall, J.; Ciaudo, C.; Allain, F. H.- T.

10.1101/572156 — molecular biology — Posted on 2019-03-09

2463 Selective autophagic clearance of protein aggregates is mediated by the autophagy receptor, TAX1BP1

Sarraf, S. A.; Shah, H. V.; Kanfer, G.; Ward, M. E.; Youle, R. J.

10.1101/558767 — cell biology — Posted on 2019-03-09

2464 Balanced internal hydration discriminates substrate binding to respiratory complex I

Teixeira, M. H.; Arantes, G. M.

10.1101/572404 — biophysics — Posted on 2019-03-09

2465 Roost selection by male northern long-eared bats (Myotis septentrionalis) in a managed fire-adapted forest

Alston, J.; Abernethy, I.; Keinath, D.; Goheen, J.

10.1101/487256 — zoology — Posted on 2019-03-08

2466 Optic flow helps explain gulls’ altitude control over seas

Serres, J. R.; Evans, T. J.; Akesson, S.; Duriez, O.; Shamoun-Baranes, J. Z.; Ruffier, F.; Hedenstrom, A.

10.1101/569194 — neuroscience — Posted on 2019-03-08

2467 Distinct Narrow and Broadband Gamma Responses in Human Visual Cortex

Bartoli, E.; Bosking, W.; Li, Y.; Beauchamp, M. S.; Yoshor, D.; Foster, B.

10.1101/572313 — neuroscience — Posted on 2019-03-08

2468 Risky Decision-Making Predicts Dopamine Release Dynamics in Nucleus Accumbens Shell

Freels, T. G.; Gabriel, D. B. K.; Lester, D. B.; Simon, N. W.

10.1101/572263 — neuroscience — Posted on 2019-03-08

2469 Connectional heterogeneity in the mouse auditory corticocollicular system

Yudintsev, G.; Asilador, A.; Coppinger, M.; Nair, K.; Prasad, M.; Llano, D. A.

10.1101/571711 — neuroscience — Posted on 2019-03-08

2470 Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins

Tyssowski, K. M.; Gray, J. M.

10.1101/572370 — neuroscience — Posted on 2019-03-08

2471 Insect-symbiont gene expression in the midgut bacteriocytes of a blood-sucking parasite

Husnik, F.; Hypsa, V.; Darby, A.

10.1101/572495 — genomics — Posted on 2019-03-08

2472 A chronology of multicellularity evolution in cyanobacteria

Hammerschmidt, K.; Landan, G.; Tria, F. D.; Dagan, T.

10.1101/570788 — evolutionary biology — Posted on 2019-03-08

2473 Associations among Fish Length, Dam Passage History, and Survival to Adulthood in Two At-Risk Species of Pacific Salmon

Faulkner, J. R.; Bellerud, B. L.; Widener, D. L.; Zabel, R. W.

10.1101/572594 — ecology — Posted on 2019-03-08

2474 COMMD1 and PtdIns(4,5)P2 interaction maintain ATP7B copper transporter trafficking fidelity in HepG2 cells

Stewart, D. J.; Short, K. K.; Maniaci, B. N.; Burkhead, J. L.

10.1101/572578 — cell biology — Posted on 2019-03-08

2475 Mechanism of pharmacochaperoning in KATP channels revealed by cryo-EM

Martin, G. M.; Sung, M. W.; Yang, Z.; Innes, L. M.; Kandasamy, B.; David, L.; Yoshioka, C.; Shyng, S.-L.

10.1101/572297 — biophysics — Posted on 2019-03-08

2476 Pervasive head-to-tail insertions of DNA templates mask desired CRISPR/Cas9-mediated genome editing events

Skryabin, B. V.; Gubar, L.; Seeger, B.; Kaiser, H.; Stegemann, A.; Roth, J.; Meuth, S. G.; Pavenstadt, H.; Sherwood, J.; Pap, T.; Wedlich-Soldner, R.; Sunderkotter, C.; Schwartz, Y. B.; Brosius, J.; Rozhdestvensky, T. S.

10.1101/570739 — genetics — Posted on 2019-03-08

2477 The Developmental Transcriptome for Lytechinus variegatus Exhibits Temporally Punctuated Gene Expression Changes

Hogan, J. D.; Keenan, J. L.; Luo, L.; Hawkins, D. Y.; Ibn-Salem, J.; Lamba, A.; Schatzberg, D.; Piacentino, M. L.; Zuch, D. T.; Core, A. B.; Blumberg, C.; Timmermann, B.; Grau, J. H.; Speranza, E.; Andrade-Navarro, M. A.; Irie, N.; Poustka, A. J.; Bradham, C.

10.1101/572388 — developmental biology — Posted on 2019-03-08

2478 In vitro transposon targeting using a catalytically inactive Cas9

Bhatt, S.; Chalmers, R.

10.1101/571653 — biochemistry — Posted on 2019-03-08

2479 Natural global motion processing by populations of direction-selective retinal ganglion cells

Cafaro, J.; Zylberberg, J.; Field, G.

10.1101/572438 — neuroscience — Posted on 2019-03-08

2480 Functionally Coherent Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling

Overton, I. M.; Sims, A. H.; Owen, J. A.; Heale, B.; Ford, M. J.; Lubbock, A. L. R.; Pairo-Castineira, E.; Essafi, A.

10.1101/455709 — systems biology — Posted on 2019-03-08

2481 To cure or not to cure: consequences of immunological interactions in CML treatment

Cesar Fassoni, A.; Roeder, I.; Glauche, I.

10.1101/494575 — systems biology — Posted on 2019-03-08

2482 12h-clock control of central dogma information flow by XBP1s

Pan, Y.; Ballance, H.; Schnytzer, Y.; Chen, X.; Levy, O.; Coarfa, C.; Zhu, B.

10.1101/559039 — systems biology — Posted on 2019-03-08

2483 Optimization of the experimental parameters of the ligase cycling reaction

Schlichting, N.; Reinhardt, F.; Jager, S.; Schmidt, M.; Kabisch, J.

10.1101/510768 — synthetic biology — Posted on 2019-03-08

2484 beditor: A computational workflow for designing libraries of guide RNAs for CRISPR-mediated base editing

Dandage, R.; Despres, P. C.; Yachie, N.; Landry, C. R.

10.1101/426973 — synthetic biology — Posted on 2019-03-08

2485 A highly predictive signature of cognition and brain atrophy for progression to Alzheimer’s dementia

Tam, A.; Dansereau, C.; Iturria-Medina, Y.; Urchs, S.; Orban, P.; Sharmarke, H.; Breitner, J.; Bellec, P.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/352344 — neuroscience — Posted on 2019-03-08

2486 Explicit Neural Models for Flip-Flops and Oscillators Generate Phenomena of Short-Term Memory and Electroencephalography

Yoder, L.

10.1101/403196 — neuroscience — Posted on 2019-03-08

2487 Pre-stimulus feedback connectivity biases the content of visual experiences

Rassi, E.; Wutz, A.; Mueller-Voggel, N.; Weisz, N.

10.1101/437152 — neuroscience — Posted on 2019-03-08

2488 Altered brain morphology in boys with attention-deficit/hyperactivity disorder with and without comorbid conduct disorder/oppositional defiant disorder

Vetter, N. C.; Backhausen, L. L.; Buse, J.; Roessner, V.; Smolka, M. N.

10.1101/553552 — neuroscience — Posted on 2019-03-08

2489 CHIME: CMOS-hosted in-vivo microelectrodes for massively scalable neuronal recordings

Kollo, M.; Racz, R. R.; Hanna, M.; Obaid, A.; Angle, M. R.; Wray, W.; Kong, Y.; Hierlemann, A.; Muller, J.; Melosh, N. A.; Schaefer, A. T.

10.1101/570069 — neuroscience — Posted on 2019-03-08

2490 Genomic changes underlying host specialization in the bee gut symbiont Lactobacillus Firm5

Ellegaard, K. M.; Brochet, S.; Bonilla-Rosso, G.; Emery, O.; Glover, N.; Hadadi, N.; Jaron, K. S.; van der Meer, J. R.; Robinson-Rechavi, M.; Sentchilo, V.; Tagini, F.; SAGE class 2016-17, ; Engel, P.

10.1101/483685 — microbiology — Posted on 2019-03-08

2491 Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy and the host’s genotype upon microbiome composition

Yin, J.; Sternes, P. R.; Wang, M.; Morrison, M.; Song, J.; Li, T.; Zhou, L.; Wu, X.; He, F.; Zhu, J.; Brown, M. A.; Xu, H.

10.1101/571430 — microbiology — Posted on 2019-03-08

2492 Unique and assay specific features of NOMe-, ATAC- and DNase I-seq data

Nordström, K.; Schmidt, F.; Gasparoni, N.; Salhab, A.; Gasparoni, G.; Kattler, K.; Müller, F.; Ebert, P.; Costa, I. G.; DEEP consortium, ; Pfeifer, N.; Lengauer, T.; Schulz, M. H.; Walter, J.

10.1101/547596 — genomics — Posted on 2019-03-08

2493 Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels.

Carlson, J. C.; Weeks, D. E.; Hawley, N. L.; Gao, G.; Cheng, H.; Naseri, T.; Reupena, M. S.; Deka, R.; McGarvey, S. T.; Minster, R. L.

10.1101/411546 — genetics — Posted on 2019-03-08

2494 Cdc14 phosphatase ensures resolution of aberrant meiotic recombination outcomes partly through activating Yen1/GEN1

Pascual-Silva, C.; Strouhalova, K.; Garside, G. B.; Arter, M.; Alvarez-Melo, D.; Bermejo, T.; San-Segundo, P. A.; Matos, J.; Geymonat, M.; Carballo, J. A.

10.1101/571083 — genetics — Posted on 2019-03-08

2495 Accurate inference of tree topologies from multiple sequence alignments using deep learning

Suvorov, A.; Hochuli, J.; Schrider, D.

10.1101/559054 — evolutionary biology — Posted on 2019-03-08

2496 When sinks become sources: adaptive colonization in asexuals

Lavigne, F.; Martin, G.; Anciaux, Y.; Papaix, J.; Roques, L.

10.1101/433235 — evolutionary biology — Posted on 2019-03-08

2497 Dengue after Zika: characterizing impacts of Zika emergence on endemic dengue transmission

Borchering, R. K.; Huang, A.; Mier-y-Teran-Romero, L.; Rojas, D. P. P.; Rodriguez-Barraquer, I.; Katzelnick, L. C.; Martinez, S. D.; King, G. D.; Cinkovich, S. C.; Lessler, J.; Cummings, D. A. T.

10.1101/567537 — epidemiology — Posted on 2019-03-08

2498 Realized generation times: contraction and impact of infectious period, reproduction number and population size

Torneri, A.; Azmon, A.; Faes, C.; Kenah, E.; Scalia Tomba, G.; Wallinga, J.; Hens, N.

10.1101/568485 — epidemiology — Posted on 2019-03-08

2499 Identification of the relative timing of infectiousness and symptom onset for outbreak control

Cope, R. C.; Ross, J. V.

10.1101/571547 — epidemiology — Posted on 2019-03-08

2500 Trajectories of change after a health-education program in Japan

Park, M.; Green, J.; Jung, H. S.; Park, Y. S.

10.1101/568584 — epidemiology — Posted on 2019-03-08

2501 Estimating the effect of the 2005 change in BCG policy in England: A retrospective cohort study

Abbott, S.; Christensen, H.; Welton, N.; Brooks-Pollock, E.

10.1101/567511 — epidemiology — Posted on 2019-03-08

2502 Reducing RSV hospitalisation in a lower-income country by vaccinating mothers-to-be and their households

Brand, S. P. C.; Munywoki, P.; Walumbe, D.; Keeling, M. J.; Nokes, D. J.

10.1101/569335 — epidemiology — Posted on 2019-03-08

2503 Correlations between stochastic endemic infection in multiple interacting subpopulations

Meakin, S.; Keeling, M.

10.1101/568667 — epidemiology — Posted on 2019-03-08

2504 The rise and fall of the new variant of Chlamydia trachomatis in Sweden: mathematical modelling study

Smid, J.; Althaus, C. L.; Low, N.; Unemo, M.; Herrmann, B.

10.1101/572107 — epidemiology — Posted on 2019-03-08

2505 Montastraea cavernosa corallite structure demonstrates distinct morphotypes across shallow and mesophotic depth zones in the Gulf of Mexico

Studivan, M. S.; Milstein, G.; Voss, J. D.

10.1101/402636 — ecology — Posted on 2019-03-08

2506 Multiple species drive flexible lake food webs with warming

Bartley, T. J.; Tunney, T. D.; Lester, N. P.; Shuter, B. J.; Hanner, R. H.; McCann, K. S.

10.1101/499400 — ecology — Posted on 2019-03-08

2507 Is the predation risk of mate-searching different between the sexes?

Torsekar, V. R.; Isvaran, K.; Balakrishnan, R.

10.1101/363507 — ecology — Posted on 2019-03-08

2508 Few Effects of a 5-week Computerized Cognitive Training Program in Healthy Older Adults

Rabipour, S.; Morrison, C.; Crompton, J.; Petrucelli, M.; Germano, M. d. O. G.; Popescu, A.; Davidson, P. S. R.

10.1101/570143 — clinical trials — Posted on 2019-03-08

2509 Respiration enhances TDP-43 toxicity, but TDP-43 retains some toxicity in the absence of respiration

Park, S.-K.; Park, S.; Liebman, S. W.

10.1101/415893 — cell biology — Posted on 2019-03-08

2510 Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice

Moreau, D.; Vacca, F.; Vossio, S.; Scott, C. C.; Colaco, A.; Paz Montoya, J.; Ferguson, C.; Damme, M.; Moniatte, M.; Parton, R. G.; Platt, F. M.; Gruenberg, J.

10.1101/416479 — cell biology — Posted on 2019-03-08

2511 Relating evolutionary selection and mutant clonal dynamics in normal epithelia

Hall, M. W. J.; Jones, P. H.; Hall, B. A.

10.1101/480756 — cancer biology — Posted on 2019-03-08

2512 Reconstructing B cell receptor sequences from short-read single cell RNA-sequencing with BRAPeS

Afik, S.; Raulet, G.; Yosef, N.

10.1101/389999 — bioinformatics — Posted on 2019-03-08

2513 MakeHub: Fully automated generation of UCSC Genome Browser Assembly Hubs

Hoff, K. J.

10.1101/550145 — bioinformatics — Posted on 2019-03-08

2514 HABIT - a webserver for interactive T cell neoepitope discovery

Martins, J.; Magalhaes, C.; Vieira, V.; Rocha, M.; Osorio, N. S.

10.1101/535716 — bioinformatics — Posted on 2019-03-08

2515 Unsupervised Toxoplasma gondii Recognition by Fuzzy Cycle Generative Adversarial Network

Li, S.; Li, A.; Lara, D. A. M.; Gomez Marin, J. E.; Zhang, Y.

10.1101/567891 — bioinformatics — Posted on 2019-03-08

2516 MAGICACT: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data.

Roopra, A.

10.1101/492744 — bioinformatics — Posted on 2019-03-08

2517 The evolution and phylodynamics of serotype A and SAT2 foot-and-mouth disease viruses in endemic regions of Africa

Lycett, S. J.; Tanya, V. N.; Hall, M.; King, D.; Mazeri, S.; Mioulet, V.; Knowles, N.; Wadsworth, J.; Bachanek-Bankowska, K.; Ngwa Victor, N.; Morgan, K. L.; Bronsvoort, M.

10.1101/572198 — epidemiology — Posted on 2019-03-08

2518 A Collaborative Multi-Model Ensemble for Real-Time Influenza Season Forecasting in the U.S.

Reich, N. G.; McGowan, C. J.; Yamana, T. K.; Tushar, A.; Ray, E. L.; Osthus, D.; Kandula, S.; Brooks, L. C.; Crawford-Crudell, W.; Gibson, G. C.; Moore, E.; Silva, R.; Biggerstaff, M.; Johansson, M.; Rosenfeld, R.; Shaman, J.

10.1101/566604 — epidemiology — Posted on 2019-03-08

2519 Older age at Initiation of Antiretroviral Therapy Predicts Low Bone Mineral Density in Children with perinatally-infected HIV in Zimbabwe

Gregson, C. L.; Hartley, A.; Majonga, E.; Mchugh, G.; Crabtree, N.; Rukuni, R.; Bandason, T.; Mukwasi, C.; Ward, K. A.; Mujuru, H.; Ferrand, R. A.

10.1101/565143 — epidemiology — Posted on 2019-03-08

2520 Circulating Lysophosphatidylcholines, Phosphatidylcholines, Ceramides, and Sphingomyelins and Ovarian Cancer Risk: a 23-year Prospective Study

Zeleznik, O. A.; Clish, C. B.; Kraft, P.; Avila-Pancheco, J.; Eliassen, A. H.; Tworoger, S. S.

10.1101/565044 — epidemiology — Posted on 2019-03-08

2521 Jag1 coordinates release from multipotency with cell fate choice in the developing pancreas

Seymour, P. A.; Collin, C. A.; Jorgensen, M. C.; Imayoshi, I.; Honnens de Lichtenberg, K. H.; Kopan, R.; Kageyama, R.; Serup, P.

10.1101/336529 — developmental biology — Posted on 2019-03-08

2522 Hippocampal transcriptomic responses to cellular dissociation

Harris, R. M.; Kao, H.-Y.; Alarcon, J. M.; Hofmann, H. A.; Fenton, A.

10.1101/153585 — neuroscience — Posted on 2019-03-08

2523 Healthy Ageing and Sentence Production: Disrupted Lexical Access in the Context of Intact Syntactic Planning

Hardy, S. M.; Segaert, K.; Wheeldon, L.

10.1101/327304 — neuroscience — Posted on 2019-03-08

2524 Sexual isolation with and without ecological isolation in marine isopods Jaera albifrons and J. praehirsuta

Ribardiere, A.; Pabion, E.; Coudret, J.; Daguin-Thiebaut, C.; Houbin, C.; Loisel, S.; Henry, S.; Broquet, T.

10.1101/260489 — evolutionary biology — Posted on 2019-03-08

2525 The NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression

Francescone, R.; Barbosa Vendramini-Costa, D.; Franco-Barraza, J.; Wagner, J.; Muir, A.; Lau, A. N.; Gabitova, L.; Pazina, T.; Gupta, S.; Luong, T.; Shah, N.; Rollins, D.; Malik, R.; Thapa, R.; Restifo, D.; Zhou, Y.; Cai, K. Q.; Hensley, H. H.; Tan, Y.; Kruger, W. D.; Devarajan, K.; Balachandran, S.; El-Deiry, W. S.; Vander Heiden, M. G.; Peri, S.; Campbell, K. S.; Astsaturov, I.; Cukierman, E.

10.1101/330209 — cancer biology — Posted on 2019-03-08

2526 Bioinformatics analysis for L polymerase homology of arenaviruses

Alrashedi, H.; Jones, I.; Mulley, G.; Neuman, B.

10.1101/178012 — bioinformatics — Posted on 2019-03-08

2527 Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949

Lind, S.; Sundqvist, M.; Holmdahl, R.; Dahlgren, C.; Forsman, H.; Olofsson, P.

10.1101/571604 — pharmacology and toxicology — Posted on 2019-03-08

2528 Fast dose fractionation using ultra-short laser accelerated proton pulses can increase cancer cell mortality, which relies on functional PARP1 protein

Bayart, E.; Flacco, A.; Delmas, O.; Pommarel, L.; Levy, D.; Cavallone, M.; Megnin-Chanet, F.; Deutsch, E.; Malka, V.

10.1101/571703 — cancer biology — Posted on 2019-03-08

2529 Bioelectrical signaling via domain wall migration

McNamara, H. M.; Salegame, R.; Al Tanoury, Z.; Xu, H.; Begum, S.; Ortiz, G.; Pourquie, O.; Cohen, A. E.

10.1101/570440 — biophysics — Posted on 2019-03-08

2530 Microsecond Molecular Dynamics Simulations of Diphtheria Toxin Translocation T-Domain pH-Dependent Unfolding in Solution

Flores-Canales, J. C.; Simakov, N. A.; Kurnikova, M. G.

10.1101/572040 — biophysics — Posted on 2019-03-08

2531 Mechanical stress compromises multicomponent efflux complexes in bacteria

Genova, L. A.; Roberts, M. F.; Wong, Y.-C.; Harper, C. E.; Santiago, A. G.; Fu, B.; Srivastava, A.; Jung, W.; Wang, L. M.; Krzeminski, Łukasz; Mao, X.; Sun, X.; Hui, C.-Y.; Chen, P.; Hernandez, C.

10.1101/571398 — biophysics — Posted on 2019-03-08

2532 Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the global transcriptional regulator Lsr2

Alqaseer, K.; Turapov, O.; Barthe, P.; Jagatia, H.; Visch, A. d.; Roumestand, C.; Wegrzyn, M.; Bartek, I. L.; Voskuil, M. I.; O'Hare, H.; Witney, A. A.; Cohen-Gonsaud, M.; Waddell, S. J.; Mukamolova, G. V.

10.1101/571406 — microbiology — Posted on 2019-03-08

2533 The level of specialization of Phytophthora infestans to potato and tomato is a biotrophy-related, stable trait

Kröner, A.; Mabon, R.; Corbiere, R.; Montarry, J.; Andrivon, D.

10.1101/571596 — evolutionary biology — Posted on 2019-03-08

2534 Expression patterns of PD-L1 and PD-1 provide rationales for immune checkpoint inhibition in soft tissue sarcomas

Orth, M. F.; Buecklein, V. L.; Kampmann, E.; Subklewe, M.; Noessner, E.; Cidre-Aranaz, F.; Romero-Perez, L.; Wehweck, F. S.; Lindner, L.; Issels, R.; Kirchner, T.; Altendorf-Hofmann, A.; Grunewald, T. G. P.; Knoesel, T.

10.1101/569418 — cancer biology — Posted on 2019-03-08

2535 Intrinsically disordered nuclear pore proteins show ideal-polymer morphologies and dynamics

Davis, L. K.; Ford, I. J.; Saric, A.; Hoogenboom, B.

10.1101/571687 — biophysics — Posted on 2019-03-08

2536 Electrospray Surface Charge Describes Protein Molecular Motion

Chalk, R.; Borkowska, O.; Azeez, K. A.; Oerum, S.; Born, P.; Gileadi, O.; Burgess-Brown, N.

10.1101/571091 — biophysics — Posted on 2019-03-08

2537 An evolutionary-conserved redox regulatory mechanism in human Ser/Thr protein kinases

Byrne, D. P.; Shrestha, S.; Kannan, N.; Eyers, P.

10.1101/571844 — biochemistry — Posted on 2019-03-08

2538 Challenges and Strategies for Recruiting Type 1 Diabetes Families in Kuwait with Strong Beliefs in Familism

Jahromi, M.; Rahma, Z.; Taha, N.; Abdullah, H.; Abraham, S.; Alhubail, A.; Al Sanae, H.; Aljaser, F.; Al Mahdi, M.; AbdulRasoul, M.; Al Khuwari, M.

10.1101/570945 — scientific communication and education — Posted on 2019-03-08

2539 A novel Ca2+-binding protein influences photosynthetic electron transport in Anabaena sp. PCC 7120

Walter, J.; Selim, K. A.; Leganes, F.; Fernandez-Pinas, F.; Vothknecht, U. C.; Forchhammer, K.; Aro, E.-M.; Gollan, P. J.

10.1101/571836 — plant biology — Posted on 2019-03-08

2540 Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution

Garcia-Campos, M. A.; Edelheit, S.; Toth, U.; Shachar, R.; Nir, R.; Lasman, L.; Brandis, A.; Hanna, J. H.; Rossmanith, W.; Schwartz, S.

10.1101/571679 — molecular biology — Posted on 2019-03-08

2541 Prevention of enteric bacterial infections and modulation of gut microbiota composition with conjugated linoleic acids producing Lactobacillus in mice

Peng, M.; Tabashsum, Z.; Patel, P.; Bernhardt, C.; Biswas, C.; Meng, J.; Biswas, D.

10.1101/571117 — microbiology — Posted on 2019-03-08

2542 QUALITY OF LIFE, SALIVARY CORTISOL AND ATOPIC DISEASES IN YOUNG CHILDREN

Rolfsjord, L. B.; Skjerven, H. O.; Bakkeheim, E.; Berents, T. L.; Carlsen, K.-H.; Carlsen, K. C. L.

10.1101/570960 — immunology — Posted on 2019-03-08

2543 Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma

10.1101/570879 — genomics — Posted on 2019-03-08

2544 The exhaustive genomic scan approach, with an application to rare-variant association analysis

Kanoungi, G.; Nothnagel, M.; Becker, T.; Drichel, D.

10.1101/571752 — genetics — Posted on 2019-03-08

2545 Fertility intentions and influential factors in Dalian urban city ---A cross-sectional study based on Universal Two-child policy in China

Qiu, H.; zhang, Q.; Zhang, J.; Ren, Y.; Zhou, X.; Li, S.; Liang, H.; Luo, J.; wang, Q.; hou, L.

10.1101/572008 — epidemiology — Posted on 2019-03-08

2546 Mortality among adults living with HIV treated for tuberculosis based on positive, negative, or no bacteriologic test results for tuberculosis: the IeDEA consortium

Humphrey, J. M.; Mpofu, P.; Pettit, A. C.; Musick, B.; Carter, E. J.; Messou, E.; Marcy, O.; Crabtree-Ramirez, B.; Yotebieng, M.; Anastos, K.; Sterling, T. R.; Yiannoutsos, C.; Diero, L.; Wools-Kaloustian, K.; See S8 Table,

10.1101/571000 — epidemiology — Posted on 2019-03-08

2547 β-Catenin tumour-suppressor activity depends on its ability to promote Pro-N-Cadherin maturation

Herrera, A.; Menendez, A.; Torroba, B.; Pons, S.

10.1101/571810 — cell biology — Posted on 2019-03-08

2548 ERK2 phosphorylates the epigenetic regulator CXXC-finger protein 1 (Cfp1)

Karra, A. S.; Klein, A. M.; Earnest, S.; Stippec, S.; Wichaidit, C.; McGlynn, K.; Trudgian, D. C.; Mirzaei, H.; Cobb, M. H.

10.1101/562173 — cell biology — Posted on 2019-03-08

2549 Quantitative high-throughput tests of ubiquitous RNA secondary structure prediction algorithms via RNA/protein binding

Becker, W. R.; Jarmoskaite, I.; Kappel, K.; Vaidyanathan, P. P.; Denny, S. K.; Das, R.; Greenleaf, W. J.; Herschlag, D.

10.1101/571588 — biophysics — Posted on 2019-03-08

2550 Double UP: efficient in utero electroporation via internal controls

Taylor, R. J.; Carrington, J.; Taylor, K. L.; Richters, K. E.; Gerlach, L. R.; Dent, E. W.

10.1101/571323 — neuroscience — Posted on 2019-03-08

2551 Salmonella Typhi survives in human macrophages by neutralizing the RAB32/BLOC-3 host-defence pathway

Baldassarre, M.; Solano-Collado, V.; Balci, A.; Wilson, H. M.; Mukhopadhyay, S.; Dougan, G.; Spano, S.

10.1101/570531 — microbiology — Posted on 2019-03-08

2552 Distinct matrix composition and mechanics in aged and estrogen-deficient mouse skin

Saville, C. R.; Mallikarjun, V.; Holmes, D. F.; Emmerson, E.; Derby, B.; Swift, J.; Sherratt, M. J.; Hardman, M. J.

10.1101/570481 — biophysics — Posted on 2019-03-08

2553 PESCA: A scalable platform for the development of cell-type-specific viral drivers

Hrvatin, S.; Tzeng, C. P.; Nagy, M. A.; Stroud, H.; Koutsioumpa, C.; Wilcox, O. F.; Griffith, E. C.; Greenberg, M. E.

10.1101/570895 — neuroscience — Posted on 2019-03-08

2554 NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-presentation and CD8 T Cell Responses

Corridoni, D.; Shiraishi, S.; Chapman, T.; Steevels, T.; Muraro, D.; Thezenas, M.-L.; Prota, G.; Chen, J.-L.; Gileadi, U.; Ternette, N.; Cerundolo, V.; Simmons, A.

10.1101/570705 — immunology — Posted on 2019-03-08

2555 GCNA preserves genome integrity and fertility across species

Bhargava, V.; Goldstein, C. D.; Russell, L.; Xu, L.; Ahmed, M.; Li, W.; Casey, A.; Servage, K.; Kollipara, R.; Picciarelli, Z.; Kittler, R.; Yatsenko, A.; Carmell, M.; Orth, K.; Amatruda, J. F.; Yanowitz, J. L.; Buszczak, M.

10.1101/570804 — developmental biology — Posted on 2019-03-08

2556 Frontal cortex tracks surprise separately for different sensory modalities but engages a common inhibitory control mechanism

Wessel, J. R.; Huber, D. E.

10.1101/572081 — neuroscience — Posted on 2019-03-08

2557 A tertiary structure protein model for the ab-initio interpretation of small angle X-ray scattering data

Prior, C.; Davies, O.; Pohl, E.

10.1101/572057 — molecular biology — Posted on 2019-03-08

2558 The Gag Protein PEG10 Binds to RNA and Regulates Trophoblast Stem Cell Lineage Specification.

Abed, M.; Verschueren, E.; Budayeva, H.; Liu, P.; Kirkpatrick, D.; Reja, R.; Kummerfeld, S.; Webster, J.; Gierke, S.; Reichelt, M.; Anderson, K.; Newman, R.; Roose-Girma, M.; Modrusan, Z.; Pektas, H.; Maltepe, E.; Newton, K.; Dixit, V.

10.1101/572016 — molecular biology — Posted on 2019-03-08

2559 Iron nanoparticle-labeled murine mesenchymal stromal cells in an osteoarthritic model persists and demonstrates anti-inflammatory mechanism of action

Hamilton, A. M.; Cheung, W.-Y.; Gomez-Aristizabal, A.; Nakamura, S.; Chaboureau, A.; Bhatt, S.; Sharma, A.; Kapoor, M.; Foster, P. J.; Viswanathan, S.

10.1101/571976 — cell biology — Posted on 2019-03-08

2560 Colony entropy - Allocation of goods in ant colonies

Greenwald, E.; Eckmann, J.-P.; Feinerman, O.

10.1101/572032 — animal behavior and cognition — Posted on 2019-03-08

2561 Effects of estrogen on Survival and Neuronal Differentiation of adult human olfactory bulb neural stem Cells Transplanted into Spinal Cord Injured Rats

Marei, H. E.; Althani, A.; Abd-Elmaksoud, A.; Kassab, M.; Farag, A.; Lashen, S.; Cenciarelli, C.; Caceci, T.; Rezk, S.

10.1101/571950 — neuroscience — Posted on 2019-03-08

2562 Effect of topical soluble epoxide hydrolase inhibition in a preclinical diabetic wound healing model.

Reisdorf, W.; Rajpal, N.; Gehman, A.; Jain, P.; Burgert, M.; Sonti, S.; Agarwal, P.; Rajpal, D.

10.1101/571984 — physiology — Posted on 2019-03-08

2563 Mutations in pmrB confer cross-resistance to the LptD inhibitor POL7080 and colistin in Pseudomonas aeruginosa

Romano, K. P.; Warrier, T.; Poulsen, B. E.; Nguyen, P. H.; Loftis, A. R.; Saebi, A.; Pentelute, B. L.; Hung, D. T.

10.1101/571224 — microbiology — Posted on 2019-03-08

2564 Autologous adipose-derived stem cell transplantation enhances healing of wound with exposed bone in a rat model

Hamada, T.; Matsubara, H.; Yoshida, Y.; Ugaji, S.; Nomura, I.; Tsuchiya, H.

10.1101/571968 — animal behavior and cognition — Posted on 2019-03-08

2565 Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy and the host’s genotype upon microbiome composition

Yin, J.; Sternes, P. R.; Wang, M.; Morrison, M.; Song, J.; Li, T.; Zhou, L.; Wu, X.; He, F.; Zhu, J.; Brown, M. A.; Xu, H.

10.1101/571430 — microbiology — Posted on 2019-03-08

2566 Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation.

Hosmillo, M.; Lu, J.; McAllaster, M. R.; Eaglesham, J. B.; Wang, X.; Emmott, E.; Domingues, P.; Chaudhry, Y.; Fitzmaurice, T. J.; Tung, M. K. H.; Panas, M.; McInerney, G.; Locker, N.; Willen, C. B.; Goodfellow, I.

10.1101/571455 — microbiology — Posted on 2019-03-08

2567 Identification of bacteria involved in the decomposition of lignocellulosic biomass treated with cow rumen fluid by metagenomic analysis

Lee, C. G.; Baba, Y.; Asano, R.; Fukuda, Y.; Tada, C.; Nakai, Y.

10.1101/570374 — microbiology — Posted on 2019-03-08

2568 Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution

Lerner, J.; Manhart, M.; Jasinska, W.; Gauthier, L.; Serohijos, A. W. R.; Bershtein, S.

10.1101/571505 — evolutionary biology — Posted on 2019-03-08

2569 Analysis of genomic loci harboring 59,732 human-specific regulatory sequences reveals unique to human regulatory patterns associated with brain development

Glinsky, G.

10.1101/432625 — genomics — Posted on 2019-03-08

2570 Nuclear Genome Size is Positively Correlated with Mean LTR Insertion Date in Fern and Lycophyte Genomes

Baniaga, A.; Barker, M. S.

10.1101/571570 — evolutionary biology — Posted on 2019-03-08

2571 NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional supply and immunosuppression

10.1101/330209 — cancer biology — Posted on 2019-03-08

2572 Reorientation and propulsion in fast-starting zebrafish larvae: an inverse dynamics analysis

Voesenek, C. J.; Pieters, R. P. M.; Muijres, F. T.; van Leeuwen, J. L.

10.1101/570812 — biophysics — Posted on 2019-03-08

2573 A simplified analytical model of sound propagationin the human ear

Gambin, W. L.

10.1101/571034 — bioengineering — Posted on 2019-03-08

2574 In vivo glucose imaging in multiple model organisms with an engineered single-wavelength sensor

Keller, J. P.; Marvin, J. S.; Lacin, H.; Lemon, W. C.; Shea, J.; Kim, S.; Lee, R. T.; Koyama, M.; Keller, P. J.; Looger, L.

10.1101/571422 — bioengineering — Posted on 2019-03-08

2575 Repositioning septins within the core particle

Mendonca, D. C.; Macedo, J. N.; Itri, R.; Guimaraes, S. L.; Barroso da Silva, F. L.; Cassago, A.; Garratt, R. C.; Portugal, R.; Araujo, A. P.

10.1101/569251 — biochemistry — Posted on 2019-03-08

2576 KLK4 inhibition by cyclic and acyclic peptides: structural and dynamical insights into standard-mechanism protease inhibitors

Riley, B. T.; Ilyichova, O.; de Veer, S.; swedberg, J.; Wilson, E.; Hoke, D. E.; Harris, J.; Buckle, A.

10.1101/570390 — biochemistry — Posted on 2019-03-08

2577 Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group

Crysnanto, D.; Obbard, D.

10.1101/429894 — evolutionary biology — Posted on 2019-03-07

2578 Prevalence, phenotype and architecture of developmental disorders caused by de novo mutation

McRae, J. F.; Clayton, S.; Fitzgerald, T. W.; Kaplanis, J.; Prigmore, E.; Rajan, D.; Sifrim, A.; Aitken, S.; Akawi, N.; Alvi, M.; Ambridge, K.; Barrett, D. M.; Bayzetinova, T.; Jones, P.; Jones, W. D.; King, D.; Krishnappa, N.; Mason, L. E.; Singh, T.; Tivey, A. R.; Ahmed, M.; Anjum, U.; Archer, H.; Armstrong, R.; Awada, J.; Balasubramanian, M.; Banka, S.; Baralle, D.; Barnicoat, A.; Batstone, P.; Baty, D.; Bennett, C.; Berg, J.; Bernhard, B.; Bevan, A. P.; Bitner-Glindzicz, M.; Blair, E.; Blyth, M.; Bohanna, D.; Bourdon, L.; Bourn, D.; Bradley, L.; Brady, A.; Brent, S.; Brewer, C.; Brunstrom,

10.1101/049056 — genetics — Posted on 2019-03-07

2579 Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblasts

Lerche, M.; Elosegui-Artola, A.; Guzman, C.; Georgiadou, M.; Kechagia, J. Z.; Gulberg, D.; Roca-Cusachs, P.; Peuhu, E.; Ivaska, J.

10.1101/570721 — cell biology — Posted on 2019-03-07

2580 A gravity-based three-dimensional compass in the mouse brain

Angelaki, D.; Ng, J.; Abrego, A. M.; Cham, H. X.; Dickman, D.; Laurens, J.

10.1101/570382 — neuroscience — Posted on 2019-03-07

2581 Nanopore sequencing for fast determination of plasmids, phages, virulence markers, and antimicrobial resistance genes in Shiga toxin-producing Escherichia coli

Gonzalez-Escalona, N.; Allard, M. W.; Brown, E.; Sharma, S.; Hoffmann, M.

10.1101/571364 — genomics — Posted on 2019-03-07

2582 Fenestrae-associated protein Plvap regulates the rate of blood-borne proteins passage into the hypophysis

Gordon, L.; Blechman, J.; Shimoni, E.; Gur, D.; Anand-Apte, B.; Levkowitz, G.

10.1101/571299 — developmental biology — Posted on 2019-03-07

2583 A Clustering Approach for Detecting Implausible Observation Values in Electronic Health Records Data

Estiri, H.; Murphy, S. N.

10.1101/570564 — bioinformatics — Posted on 2019-03-07

2584 μECoG Recordings Through a Thinned Skull

Brodnick, S. K.; Ness, J. P.; Richner, T. J.; Thongpang, S.; Novello, J.; Hayat, M.; Cheng, K. P.; Krugner-Higby, L.; Suminski, A. J.; Ludwig, K. A.; Williams, J. C.

10.1101/564146 — neuroscience — Posted on 2019-03-07

2585 Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data

Gervin, K.; Salas, L. A.; Bakulski, K. M.; van Zelm, M. C.; Koestler, D. C.; Wiencke, J. K.; Duijts, L.; Moll, H. A.; Kelsey, K. T.; Kobor, M. S.; Lyle, R.; Christensen, B. C.; Felix, J.; Jones, M. J.

10.1101/570457 — bioinformatics — Posted on 2019-03-07

2586 A novel structure-based control method for controlling complex large scale nonlinear dynamical networks

Guo, W.-F.; Zhang, S.-W.; Zeng, T.; Li, Y.; Gao, J.; Chen, L.

10.1101/503565 — systems biology — Posted on 2019-03-07

2587 Genetic determinants of gut microbiota composition and bile acid profiles in mice

Kemis, J. H.; Linke, V.; Barrett, K. L.; Boehm, F. J.; Traeger, L. L.; Keller, M. P.; Rabaglia, M. E.; Schueler, K. L.; Stapleton, D. S.; Gatti, D. M.; Churchill, G. A.; Amador-Noguez, D.; Russell, J. D.; Yandell, B. S.; Broman, K. W.; Coon, J. J.; Attie, A. D.; Rey, F. E.

10.1101/571075 — systems biology — Posted on 2019-03-07

2588 Native protein delivery into rice callus using ionic complexes of protein and cell-penetrating peptides

Guo, B.; Itami, J.; Oikawa, K.; Motoda, Y.; Kigawa, T.; Numata, K.

10.1101/570853 — plant biology — Posted on 2019-03-07

2589 A high-throughput delayed fluorescence method reveals underling differences in the control of circadian rhythms in Triticum aestivum and Brassica napus

Rees, H.; Duncan, S.; Gould, P.; Wells, R.; Greenwood, M.; Brabbs, T.; Hall, A.

10.1101/570572 — plant biology — Posted on 2019-03-07

2590 Comparison between proton magnetic resonance spectroscopy and high-performance liquid chromatography to quantify muscle carnosine in humans

Silva, V. d. E.; Painelli, V. d. S.; Shinjo, S. K.; Cilli, E. M.; Sale, C.; Gualano, B.; Otaduy, M. C.; Artioli, G. G.

10.1101/568923 — physiology — Posted on 2019-03-07

2591 Spontaneous network activity <35 Hz accounts for variability in stimulus-induced gamma responses

Hirschmann, J.; Baillet, S.; Schnitzler, A.; Woolrich, M.; Vidaurre, D.; Florin, E.

10.1101/381236 — neuroscience — Posted on 2019-03-07

2592 N-glycosylation of the protein disulfide isomerase Pdi1 ensures Ustilago maydis virulence

Marin-Menguiano, M.; Moreno-Sanchez, I.; Barrales, R. R.; Fernandez-Alvarez, A.; Ibeas, J. I.

10.1101/571125 — microbiology — Posted on 2019-03-07

2593 Leishmania major degrades murine CXCL1 - an immune evasion strategy

Yorek, M. S.; Poudel, B.; Mazgaeen, L.; Pope, R. M.; Wilson, M. E.; Gurung, P.

10.1101/571141 — microbiology — Posted on 2019-03-07

2594 The Genomic Landscape of Centromeres in Cancers

Saha, A.; Mourad, M.; Kaplan, M. H.; Chefetz, I.; Malek, S. N.; Buckanovich, R.; Markovitz, D. M.; Contreras-Galindo, R.

10.1101/505800 — genomics — Posted on 2019-03-07

2595 Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of hexaploid wheat and diploid Aegilops tauschii

Lu, F.-H.; McKenzie, N.; Gardiner, L.-J.; Luo, M.; Hall, A.; Bevan, M. W.

10.1101/571133 — genomics — Posted on 2019-03-07

2596 Epistasis detectably alters correlations between genomic sites in a narrow parameter window

Pedruzzi, G.; Rouzine, I. M.

10.1101/570903 — genetics — Posted on 2019-03-07

2597 Cohesin and microtubule dependent mechanisms regulate sister centromere fusion during meiosis I

McKim, K. S.; Wang, L.-I.; Das, A.

10.1101/571067 — genetics — Posted on 2019-03-07

2598 Cdc14 phosphatase ensures resolution of aberrant meiotic recombination outcomes partly through activating Yen1/GEN1

Pascual-Silva, C.; Strouhalova, K.; Garside, G. B.; Arter, M.; Alvarez-Melo, D.; Bermejo, T.; San-Segundo, P. A.; Matos, J.; Geymonat, M.; Carballo, J. A.

10.1101/571083 — genetics — Posted on 2019-03-07

2599 Generation of a white-albino phenotype from cobalt blue and yellow-albino trouts: inheritance pattern and chromatophores analysis

Hattori, R. S.; Yoshinaga, T. T.; Butzge, A. J.; Hattori-Ihara, S.; Tsukamoto, R. Y.; Takahashi, N. S.; Tabata, Y. A.

10.1101/570861 — genetics — Posted on 2019-03-07

2600 A Bayesian method using sparse data to estimate penetrance of disease-associated genetic variants

Kroncke, B.; Smith, D.; Glazer, A. M.; Roden, D. M.; Blume, J. D.

10.1101/571158 — genetics — Posted on 2019-03-07

2601 Direct inference of the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii

Keightley, P. D.; Boendel, K.; Kraemer, S.; Samuels, T.; McClean, D.; Lachapelle, J.; Ness, R.; Colegrave, N.

10.1101/571018 — evolutionary biology — Posted on 2019-03-07

2602 An ancient lineage of highly divergent parvoviruses infects both vertebrate and invertebrate hosts.

Gifford, R. J.; Agbandje-McKenna, M.; de Souza, W. M.; Penzes, J.

10.1101/571109 — evolutionary biology — Posted on 2019-03-07

2603 Signatures of Environmental Adaptation During Range Expansion of Wild Common Bean (Phaseolus vulgaris)

Ariani, A.; Gepts, P.

10.1101/571042 — ecology — Posted on 2019-03-07

2604 Nijmegen Breakage Syndrome (NBS) is a telomeropathy: analysis of telomere length in NBS homo- and heterozygotes and humanized Nbs ice

Habib, R.; Kim, R.; Neitzel, H.; Demuth, I.; Chrzanowska, K.; Seemanova, E.; Faber, R.; Digweed, M.; Jäger, K.; Sperling, K.; Walter, M.

10.1101/571026 — cancer biology — Posted on 2019-03-07

2605 Long-lasting effects of proanthocyanidins in rat prevent cafeteria diet effects by limiting adipose tissue accrual

Ardevol, A.; Gines, I.; GIL-CARDOSO, K.; Serrano, J.; CASANOVA-MARTI, A.; Lobato, M.; Terra, X.; Blay, M.; Pinent, M.

10.1101/570994 — biochemistry — Posted on 2019-03-07

2606 Mapping Lung Cancer Epithelial-Mesenchymal Transition States and Trajectories with Single-Cell Resolution

Karacosta, L. G.; Anchang, B.; Ignatiadis, N.; Kimmey, S. C.; Benson, J. A.; Shrager, J. B.; Tibshirani, R.; Bendall, S. C.; Plevritis, S. K.

10.1101/570341 — systems biology — Posted on 2019-03-07

2607 Genotype-free demultiplexing of pooled single-cell RNA-seq

Xu, J.; Falconer, C.; Coin, L.

10.1101/570614 — bioinformatics — Posted on 2019-03-07

2608 Acute regulation of habituation learning via posttranslational palmitoylation

Nelson, J. C.; Witze, E.; Ma, Z.; Ciocco, F.; Frerotte, A.; Foskett, J. K.; Granato, M.

10.1101/570044 — neuroscience — Posted on 2019-03-07

2609 Reduced Default Mode Network Functional Connectivity in Patients with Recurrent Major Depressive Disorder

Yan, C.-G.; Chen, X.; Li, L.; Castellanos, F. X.; Bai, T.-J.; Bo, Q.-J.; Chen, G.-M.; Chen, N.-X.; Chen, W.; Cheng, C.; Cheng, Y.-Q.; Cui, X.-L.; Duan, J.; Fang, Y.-R.; Gong, Q.-Y.; Guo, W.-B.; Hou, Z.-H.; Hu, L.; Kuang, L.; Li, F.; Li, K.-M.; Li, T.; Liu, Y.-S.; Liu, Z.-N.; Long, Y.-C.; Luo, Q.-H.; Meng, H.-Q.; Peng, D.-H.; Qiu, H.-T.; Qiu, J.; Shen, Y.-D.; Shi, Y.-S.; Si, T.-M.; Wang, C.-Y.; Wang, F.; Wang, K.; Wang, L.; Wang, X.; Wang, Y.; Wu, X.-P.; Wu, X.-R.; Xie, C.-M.; Xie, G.-R.; Xie, H.-Y.; Xie, P.; Xu, X.-F.; Yang, H.; Yang, J.; Yao, J.-S.; Yao, S.-Q.; Yin, Y.-Y.; Yuan, Y.-G.; Zhang,

10.1101/321745 — neuroscience — Posted on 2019-03-07

2610 Brain Age Prediction: Cortical and Subcortical Shape Covariation in the Developing Human Brain

Zhao, Y.; Klein, A.; Castellanos, F.; Milham, M. P.

10.1101/570333 — neuroscience — Posted on 2019-03-07

2611 Manure substitution of chemical fertilizer affect soil microbial community diversity, structure and function in greenhouse vegetable production systems

Luan, H.; Gao, W.; Huang, S.; Tang, J.; Li, M.; Zhang, H.; Chen, X.

10.1101/570986 — microbiology — Posted on 2019-03-07

2612 Identification and characterization of putative Aeromonas spp. T3SS effectors

Rangel, L. T.; Marden, J.; Colston, S.; Setubal, J. C.; Graf, J.; Gogarten, J. P.

10.1101/570887 — microbiology — Posted on 2019-03-07

2613 Hybrid assembly of the genome of the entomopathogenic nematode Steinernema carpocapsae identifies the X-chromosome

Mortazavi, A.; Macchietto, M.; Serra, L.; Macias-Munoz, A.; McGill, C. J.; Rodriguez, I. M.; Rodriguez, B.; Murad, R.

10.1101/571265 — genomics — Posted on 2019-03-07

2614 Mapping Histone Modifications in Low Cell Number and Single Cells Using Antibody-guided Chromatin Tagmentation (ACT-seq)

Carter, B.; Ku, W. L.; Tang, Q.; Zhao, K.

10.1101/571208 — genomics — Posted on 2019-03-07

2615 Identification of differentially expressed genes in hepatocellular carcinoma by integrated bioinformatic analysis

Yan, G.; Liu, Z.

10.1101/570846 — genetics — Posted on 2019-03-07

2616 Changes in the Physicochemical Properties and Microbial Communities of Rhizospheric Soil after Cassava/Peanut Intercropping

Tang, X.; Luo, S.; Huang, Z.; Wu, H.; Wang, J.; Shi, G.; He, L.; Xiong, F.; Jiang, J.; Liu, J.; Liao, G.; Tang, R.; He, L.

10.1101/570937 — ecology — Posted on 2019-03-07

2617 Interkinetic nuclear migration in the zebrafish retina as a diffusive process

Azizi, A.; Herrmann, A.; Wan, Y.; Buse, S. J.; Keller, P.; Goldstein, R. E.; Harris, W. A.

10.1101/570606 — developmental biology — Posted on 2019-03-07

2618 GCNA interacts with Spartan and Topoisomerase II to regulate genome stability.

Davis, G. M.; Dokshin, G.; Sawle, A. D.; Eldridge, M. D.; Romer, K. A.; Gourley, T. E.; Molesworth, L. W.; Tatnell, H. R.; Ozturk, A. R.; de Rooij, D. G.; Hannon, G. J.; Page, D. C.; Mello, C. C.; Carmell, M. A.

10.1101/570200 — developmental biology — Posted on 2019-03-07

2619 A weak Foxp3 hypomorph enhances spontaneous and therapeutic immune surveillance of cancer in mice

Almeida-Santos, J.; Bergman, M.-L.; Cabral, I. A.; Correia, V.; Caramalho, I.; Demengeot, J.

10.1101/570671 — cancer biology — Posted on 2019-03-07

2620 Cdc42EP5/BORG3 coordinates septin and actin networks to promote actomyosin function and melanoma invasion and metastasis

Farrugia, A. J.; Orgaz, J. L.; Sanz-Moreno, V.; Calvo, F.

10.1101/570747 — cancer biology — Posted on 2019-03-07

2621 Effect of Saudi and Egyptian pomegranate polyphenols in regulating the activity of PON1, PON2 and lipid profile for preventing coronary heart disease

BinMowyna, M. N.; Binobead, M. A.; Al Badr, N. A.; AlSedairy, S. A.; Elredh, I. A. R.; Al-Qahtani, W. S.

10.1101/570838 — biochemistry — Posted on 2019-03-07

2622 An abscisic acid (ABA) homeostasis regulated by its production, catabolism and transport in peanut leaves in response to drought stress

Long, H.; Zheng, Z.; Zhang, Y.; Xing, P.; Wan, X.; Zheng, Y.; Li, L.

10.1101/569848 — plant biology — Posted on 2019-03-07

2623 Approach for Semi-Automated Measurement of Fiber Diameter in Murine and Canine Skeletal Muscle

Stevens, C. R.; Sledziona, M.; Moore, T.; Dong, L.; Cheetham, J.

10.1101/569780 — neuroscience — Posted on 2019-03-07

2624 Diffusion Tensor Tractography of Brainstem Fibers and Its Application in Pain

Zhang, Y.; Vakhtin, A. A.; Jennings, J. S.; Massaband, P.; Wintermark, M.; Craig, P. L.; Ashford, J. W.; Clark, D. J.; Furst, A. J.

10.1101/569723 — neuroscience — Posted on 2019-03-07

2625 Sterol-O acyltransferase 1 is inhibited by gga-miR-181a-5p and gga-miR-429-3p through the TGFβ pathway in endodermal epithelial cells of Japanese quail

Lin, H.-J.; Lin, C.-W.; Mersmann, H. J.; Ding, S.-T.

10.1101/569806 — molecular biology — Posted on 2019-03-07

2626 Mechanical, physical and chemical characterisation of mycelium-based composites with different types of lignocellulosic substrates

Elsacker, E.; Vandelook, S.; Brancart, J.; Peeters, E.; De Laet, L.

10.1101/569749 — microbiology — Posted on 2019-03-07

2627 HRPK-1, a conserved KH-domain protein, modulates microRNA activity during Caenorhabditis elegans development

Zinovyeva, A.; Li, L.; Veksler-Lublinsky, I.

10.1101/569905 — genetics — Posted on 2019-03-07

2628 A causal approach to understanding management factors, reproductive underperformance and reproductive infections in dairy cattle

Skjerve, E.; Softic, A.; Godfroid, J.; Granquist, E.; Asmare, K.; Fejzic, N.

10.1101/569764 — epidemiology — Posted on 2019-03-07

2629 In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex which supports oogenesis

Guioli, S.; Zhao, D.; Nandi, S.; Clinton, M.; Lovell-Badge, R.

10.1101/568691 — developmental biology — Posted on 2019-03-07

2630 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth

Galdi, P.; Blesa Cabez, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P.

10.1101/569319 — neuroscience — Posted on 2019-03-07

2631 Persistence of neuronal representations through time and damage in the hippocampus.

Gonzalez, W. G.; Zhang, H.; Harutyunyan, A.; Lois, C.

10.1101/559104 — neuroscience — Posted on 2019-03-07

2632 Interpretable genotype-to-phenotype classifiers with performance guarantees

Drouin, A.; Letarte, G.; Raymond, F.; Marchand, M.; Corbeil, J.; Laviolette, F.

10.1101/388348 — genomics — Posted on 2019-03-07

2633 The flickering connectivity system of the north Andean paramos

Flantua, S. G. A.; O'Dea, A.; Onstein, R. E.; Hooghiemstra, H.

10.1101/569681 — ecology — Posted on 2019-03-07

2634 A \"Dirty\" Footprint: Anthropogenic Soils Promote Biodiversity in Amazonian Rainforests

Demetrio, W. C.; Conrado, A. C.; Acioli, A.; Ferreira, A. C.; Bartz, M. L.; James, S. W.; da Silva, E.; Maia, L. S.; Martins, G. C.; Macedo, R. S.; Stanton, D. W. G.; Lavelle, P.; Velasquez, E.; Zangerle, A.; Tapia-Coral, S.; Barbosa, R.; Muniz, A. W.; Santos, A.; Ferreira, T.; Segalla, R. F.; Decaens, T.; PenaVenegas, C. P.; Nadolny, H. S.; Maia, C. S.; Pasini, A.; Motta, A. F.; Taube Junior, P. S.; Silva, T. A.; Rebellato, L.; Oliveira Junior, R. C.; Neves, E. G.; Pinto Lima, H.; Feitosa, R.; Vidal Torrado, P.; McKey, D.; Clement, C. R.; Shock, M. P.; Teixeira, W. G.; Carlos V. Motta, A.; de

10.1101/552364 — zoology — Posted on 2019-03-07

2635 A hierarchical approach to model decision making: a study in chemotactic behavior of Escherichia coli

Vafadar, S.; Kavousi, K.; Safdari, H.; Kalirad, A.; Sadeghi, M.

10.1101/569277 — systems biology — Posted on 2019-03-07

2636 Whisking signals motor preparation and the behavioral state of mice

Dominiak, S. E.; Nashaat, M. A.; Sehara, K.; Oraby, H.; Larkum, M. E.; Sachdev, R. N.

10.1101/568030 — neuroscience — Posted on 2019-03-07

2637 Sweet revenge - Streptococcus pyogenes showcases first example of immune evasion through specific IgG glycan hydrolysis

Naegeli, A.; Bratanis, E.; Karlsson, C.; Shannon, O.; Kalluru, R.; Linder, A.; Malmström, J.; Collin, M.

10.1101/544064 — microbiology — Posted on 2019-03-07

2638 Ubiquitin-dependent and -independent roles of E3 ligase RIPLET in innate immunity

Cadena, C.; Ahmad, S.; Xavier, A.; Willemsen, J.; Park, S.; Park, J. W.; Oh, S.-W.; Fujita, T.; Hou, F.; Binder, M.; Hur, S.

10.1101/367656 — immunology — Posted on 2019-03-07

2639 Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

Lewis, K. J. S.; Richards, A.; Leonenko, G.; Jones, S. E.; Jones, H.; Gordon-Smith, K.; Forty, L.; Escott-Price, V.; Owen, M. J.; Weedon, M. N.; Jones, L.; Craddock, N.; Jones, I.; O'Donovan, M. C.; Di Florio, A.

10.1101/569376 — genomics — Posted on 2019-03-07

2640 A rapid and simple method for assessing and representing genome sequences relatedness

Briand, M.; Bouzid, M.; Hunault, G.; Legeay, M.; Fischer-Le Saux, M.; Barret, M.

10.1101/569640 — genomics — Posted on 2019-03-07

2641 HiVA: an integrative wet- and dry-lab platform for haplotype and copy number analysis of single-cell genomes

Zamani Esteki, M.; Ardeshirdavani, A.; Alcaide, D.; Masset, H.; Ding, J.; Sifrim, A.; Kumar, P.; Dimitriadou, E.; Aerts, J.; Voet, T.; Moreau, Y.; Vermeesch, J. R.

10.1101/564914 — genomics — Posted on 2019-03-07

2642 On the cross-population portability of gene expression prediction models

Keys, K. L.; Mak, A. C. Y.; White, M. J.; Eckalbar, W.; Dahl, A. J.; Mefford, J.; Mikhaylova, A. V.; Contreras, M. G.; Elhawary, J. R.; Eng, C.; Hu, D.; Huntsman, S.; Oh, S. S.; Salazar, S.; Lenoir, M. A.; Ye, C. J.; Thornton, T. A.; Zaitlen, N.; Burchard, E. G.; Gignoux, C. R.

10.1101/552042 — genomics — Posted on 2019-03-07

2643 Cleaning genotype data from Diversity Outbred mice

Broman, K. W.; Gatti, D. M.; Svenson, K. L.; Sen, S.; Churchill, G. A.

10.1101/518308 — genetics — Posted on 2019-03-07

2644 Adaptation and the Parliament of Genes

Scott, T. W.; West, S. A.

10.1101/526970 — evolutionary biology — Posted on 2019-03-07

2645 Environmentally-driven dynamic parameters in mechanistic movement models reveal complex migratory pacing in a soaring bird

Eisaguirre, J.; Auger-Methe, M.; Barger, C.; Lewis, S.; Booms, T.; Breed, G.

10.1101/465427 — ecology — Posted on 2019-03-07

2646 A homozygous genome-edited Sept2-EGFP fibroblast cell line

Banko, M.; Mucha-Kruczynska, I.; Weise, C.; Heyd, F.; Ewers, H.

10.1101/570622 — cell biology — Posted on 2019-03-07

2647 The midbody interactome reveals new unexpected roles for PP1 phosphatases in cytokinesis

Capalbo, L.; Bassi, Z.; Geymonat, M.; Todesca, S.; Copoiu, L.; Enright, A.; Callaini, G.; Riparbelli, M. G.; Yu, L.; Choudhary, J.; Ferrero, E.; Wheatley, S.; Douglas, M.; Mishima, M.; D'Avino, P. P.

10.1101/569459 — cell biology — Posted on 2019-03-07

2648 Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties

Soroor, F.; Kim, M. S.; Palander, O.; Balachandran, Y.; Collins, R.; Benlekbir, S.; Rubinstein, J.; Trimble, W. S.

10.1101/569871 — cell biology — Posted on 2019-03-07

2649 EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake

Matthaeus, C.; Lahmann, I.; Kunz, S.; Jonas, W.; Melo, A. A.; Lehmann, M.; Larsson, E.; Lundmark, R.; Kern, M.; Blueher, M.; Hauke, V.; Mueller, D. N.; Schuermann, A.; Birchmeier, C.; Daumke, O.

10.1101/511709 — cell biology — Posted on 2019-03-07

2650 Attack and defence in cellular decision-making: lessons from machine learning

Rademaker, T. J.; Bengio, E.; Francois, P.

10.1101/366724 — biophysics — Posted on 2019-03-07

2651 Energy Landscape of the Domain Movement in Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase

de Azevedo, E. C.; Nascimento, A. S.

10.1101/535138 — biophysics — Posted on 2019-03-07

2652 MultiCapsNet: a interpretable deep learning classifier integrate data from multiple sources

Wang, L.; Miao, X.; Zhang, J.; Cai, J.

10.1101/570507 — bioinformatics — Posted on 2019-03-07

2653 MAGICACT: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data.

Roopra, A.

10.1101/492744 — bioinformatics — Posted on 2019-03-07

2654 Bacterial defiance as a form of prodrug failure

Holt, B. A.; Curro, I.; Kwong, G. A.

10.1101/556951 — bioengineering — Posted on 2019-03-07

2655 Can sleep protect memories from catastrophic forgetting?

Gonzalez, O. C.; Sokolov, Y.; Krishnan, G.; Bazhenov, M.

10.1101/569038 — neuroscience — Posted on 2019-03-07

2656 Extracellular vesicle-mediated RNA release in Histoplasma capsulatum

Alves, L. R.; Peres da Silva, R.; Sanchez, D. A.; Zamith-Miranda, D.; Rodrigues, M. L.; Goldenberg, S.; Puccia, R.; Nosanchuk, J. D.

10.1101/570291 — microbiology — Posted on 2019-03-07

2657 A simple microbiome in the European common cuttlefish, Sepia officinalis

Lutz, H. L.; Ramirez-Puebla, T.; Abbo, L.; Durand, A.; Schlundt, C.; Sjaarda, A. K.; Gottel, N.; Hanlon, R.; Gilbert, J.; Mark Welch, J.

10.1101/440677 — microbiology — Posted on 2019-03-07

2658 Experimental introgression to evaluate the impact of sex specific traits on Drosophila melanogaster incipient speciation

Cortot, J.; Farine, J.-P.; Houot, B.; Everaerts, C.; Ferveur, J.-F.

10.1101/569699 — evolutionary biology — Posted on 2019-03-07

2659 Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group

Crysnanto, D.; Obbard, D.

10.1101/429894 — evolutionary biology — Posted on 2019-03-07

2660 Extreme midsummer rainfall event drives early onset cyanobacterial bloom

Larsen, M. L.; Baulch, H. M.; Schiff, S. L.; Simon, D. F.; Sauve, S.; Venkiteswaran, J. J.

10.1101/570275 — ecology — Posted on 2019-03-07

2661 A non-canonical role of polo-like kinase-4 in adventitial fibroblast cell type transition

Li, J.; Urabe, G.; Zhang, M.; Huang, Y.; Wang, B.; Marcho, L.; Shen, H.; Kent, K. C.; Guo, L.-W.

10.1101/570267 — cell biology — Posted on 2019-03-07

2662 A cancer-associated missense mutation in PP2A-Aα increases centrosome clustering during mitosis

V. Antao, N.; Marcet-Ortega, M.; Cifani, P.; Kentsis, A.; A. Foley, E.

10.1101/570978 — cell biology — Posted on 2019-03-07

2663 SPARSE INFOMAX BASED ON HOYER PROJECTION AND ITS APPLICATION TO SIMULATED STRUCTURAL MRI AND SNP DATA

Duan, K.; Silva, R. F.; Chen, J.; Lin, D.; Calhoun, V. D.; Liu, J.

10.1101/570317 — bioengineering — Posted on 2019-03-07

2664 Analysis of the frequency and pathogenicity of ATP7B variants in a genomic dataset: implications for Wilson disease prevalence and penetrance

Wallace, D. F.; Dooley, J. S.

10.1101/499285 — genetics — Posted on 2019-03-07

2665 Temporal dynamics of inhalation-linked activity across defined subpopulations of mouse olfactory bulb neurons imaged in vivo.

Short, S. M.; Wachowiak, M.

10.1101/558999 — neuroscience — Posted on 2019-03-07

2666 Use of a filter cartridge combined with intra-cartridge bead beating improves detection of microbial DNA from water samples

Ushio, M.

10.1101/435305 — ecology — Posted on 2019-03-07

2667 Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells

Guo, T.; Luna, A.; Koh, C. C.; Rajapakse, V.; Wu, Z.; Menden, M. P.; Cheng, Y.; Calzone, L.; Martignetti, L.; Ori, A.; Iskar, M.; Gillet, L.; Zhong, Q.; Varma, S.; Schmitt, U.; Qiu, P.; Sun, Y.; zhu, Y.; Wild, P.; Mathew, G.; Bork, P.; Beck, M.; Saez-Rodriguez, J.; Reinhold, W.; Sander, C.; Pommier, Y.; Aebersold, R.

10.1101/268953 — systems biology — Posted on 2019-03-07

2668 Amelioration of Brain Histone Methylopathies by Balancing a Writer-Eraser Duo KMT2A-KDM5C

Vallianatos, C. N.; Raines, B.; Porter, R. S.; Wu, M. C.; Garay, P. M.; Collette, K. M.; Seo, Y. A.; Dou, Y.; Keegan, C. E.; Tronson, N.; Iwase, S.

10.1101/567917 — genetics — Posted on 2019-03-07

2669 A Multi-Domain Task Battery Reveals Functional Boundaries in the Human Cerebellum

King, M.; Hernandez-Castillo, C. R.; Poldrack, R. A.; Ivry, R.; Diedrichsen, J.

10.1101/423509 — neuroscience — Posted on 2019-03-06

2670 Structure-Unbinding Kinetics Relationship of p38 MAPK Inhibitors

Ge, X.; Tan, H.; Xie, L.

10.1101/510255 — pharmacology and toxicology — Posted on 2019-03-06

2671 Fractionation of impulsive and compulsive trans-diagnostic phenotypes and their longitudinal associations

Chamberlain, S. R.; Tiego, J.; Fontenelle, L.; Hook, R.; Segrave, R.; Hauser, T.; Dolan, R.; Goodyer, I.; Bullmore, E.; Grant, J.; Yucel, M.

10.1101/570218 — neuroscience — Posted on 2019-03-06

2672 The time-course of component processes of selective attention

Wen, T.; Duncan, J.; Mitchell, D. J.

10.1101/511022 — neuroscience — Posted on 2019-03-06

2673 Corrective muscle activity reveals subject-specific sensorimotor recalibration.

Iturralde, P. A.; Torres-Oviedo, G.

10.1101/372359 — neuroscience — Posted on 2019-03-06

2674 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth

Galdi, P.; Blesa Cabez, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P.

10.1101/569319 — neuroscience — Posted on 2019-03-06

2675 How sample heterogeneity can obscure the signal of microbial interactions

Armitage, D. W.; Jones, S. E.

10.1101/520668 — microbiology — Posted on 2019-03-06

2676 Single-cell RNA-seq reveals spatially restricted multicellular fibrotic niches during lung fibrosis

Joshi, N.; Watanabe, S.; Verma, R.; Jablonski, R. P.; Chen, C.-I.; Cheresh, P.; Reyfman, P. A.; McQuattie-Pimentel, A. C.; Sichizya, L.; Flozak, A. S.; Gottardi, C. J.; Cuda, C. M.; Perlman, H.; Jain, M.; Kamp, D. W.; Budinger, G. S.; Misharin, A. V.

10.1101/569855 — immunology — Posted on 2019-03-06

2677 Bone marrow transplantation rescues monocyte recruitment defect and improves cystic fibrosis in mice

Fan, Z.; Miller, J.; Herro, R.; Ehinger, E.; Conrad, D. J.; Mikulski, Z.; Zhu, Y. P.; Marcovecchio, P. M.; Hedrick, C. C.; Ley, K.

10.1101/570135 — immunology — Posted on 2019-03-06

2678 Genomic architecture of phenotypic plasticity of complex traits in tetraploid wheat in response to water stress

Fatiukha, A.; Deblieck, M.; Klymiuk, V.; Merchuk-Ovnat, L.; Peleg, Z.; Ordon, F.; Fahima, T.; Korol, A. B.; Saranga, Y.; Krugman, T.

10.1101/565820 — genetics — Posted on 2019-03-06

2679 Neuropsychiatric Phenotypes in 3q29 Deletion Syndrome and Novel Features of ASD: Results from the 3q29 Registry

Pollak, R. M.; Murphy, M. M.; Epstein, M. P.; Zwick, M. E.; Klaiman, C.; Saulnier, C. A.; The Emory 3q29 Project, ; Mulle, J. G.

10.1101/386243 — genetics — Posted on 2019-03-06

2680 Boosting Diabetes and Pre-Diabetes Screening in Rural Ghana

Crimi, A.; Nyarko, B. E.; Amoah, R. S.

10.1101/278960 — epidemiology — Posted on 2019-03-06

2681 Vector competence for Zika virus is not affected by mosquito age but vectorial capacity of Ae. aegypti is multifactorial and age-dependent

Mayton, E. H.; Tramonte, A. R.; Christofferson, R. C.

10.1101/552125 — ecology — Posted on 2019-03-06

2682 A survey of fishes of Hombolo Lake, Dodoma, Tanzania, with evidence for local extinction of a native tilapia as a consequence of stocking

Turner, G. F.; Ngatunga, B. P.; Genner, M. J.

10.1101/452847 — ecology — Posted on 2019-03-06

2683 A reformulation of the selection ratio shed light on resource selection functions and leads to a unified framework for habitat selection studies.

Chamaille-Jammes, S.

10.1101/565838 — ecology — Posted on 2019-03-06

2684 FAIM opposes stress-induced loss of viability and blocks the formation of protein aggregates

Kaku, H.; Rothstein, T. L.

10.1101/569988 — cell biology — Posted on 2019-03-06

2685 Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma

Thomaz, A.; Pinheiro, K. d. V.; Souza, B. K.; Gregianin, L.; Brunetto, A. L.; Brunetto, A. T.; de Farias, C. B.; Jaeger, M. d. C.; Ramaswamy, V.; Nor, C.; Taylor, M. D.; Roesler, R.

10.1101/566000 — cancer biology — Posted on 2019-03-06

2686 Studies of allosteric coupling in KcsA using a constitutively open mutant

Sun, Z.; Xu, Y.; Zhang, D.; McDermott, A. E.

10.1101/567024 — biophysics — Posted on 2019-03-06

2687 Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis

Durif, G.; Modolo, L.; Mold, J. E.; Lambert-Lacroix, S.; Picard, F.

10.1101/211938 — bioinformatics — Posted on 2019-03-06

2688 LinkedSV: Detection of mosaic structural variants from linked-read exome and genome sequencing data

Fang, L.; Kao, C.; Gonzalez, M. V.; Mafra, F. A.; Pellegrino da Silva, R.; Li, M.; Wenzel, S.; Wimmer, K.; Hakonarson, H.; Wang, K.

10.1101/409789 — bioinformatics — Posted on 2019-03-06

2689 Interpretation of Omics dynamics in a single subject using local estimates of dispersion between two transcriptomes

Li, Q.; Rachid Zaim, S.; Aberasturi, D.; Berghout, J.; Li, H.; Vitali, F.; Kenost, C.; Zhang, H. H.; Lussier, Y. A.

10.1101/405332 — bioinformatics — Posted on 2019-03-06

2690 Genetic Basis of Alternative Polyadenylation is an Emerging Molecular Phenotype for Human Traits and Diseases

Li, L.; Gao, Y.; Peng, F.; Wagner, E. J.; Li, W.

10.1101/570176 — bioinformatics — Posted on 2019-03-06

2691 Estimating Residue-Specific Accuracies of Protein Structure Models Using Molecular Dynamics Simulations

Hu, J.-H.; Xun, S.-N.; Wu, H.-N.; Wu, Y.-D.; Jiang, F.

10.1101/439760 — bioinformatics — Posted on 2019-03-06

2692 A robotic platform for fluidically-linked human body-on-chips experimentation

Novak, R.; Ingram, M.; Clauson, S.; Das, D.; Delahanty, A.; Herland, A.; Maoz, B.; Jeanty, S. S. F.; Somayaji, M. R.; Burt, M.; Calamari, E.; Chalkiadaki, A.; Cho, A.; Choe, Y.; Chou, D. B.; Cronce, M.; Dauth, S.; Divic, T.; Fernandez-Alcon, J.; Ferrante, T.; Ferrier, J.; Fitzgerald, E. A.; Fleming, R.; Jalili Firoozinezhad, S.; Grevesse, T.; Goss, J. A.; Hamkins-Indik, T.; Henry, O.; Hinojosa, C.; Huffstater, T.; Jang, K.-J.; Kujala, V.; Leng, L.; Mannix, R.; Milton, Y.; Nawroth, J.; Nestor, B. A.; Ng, C. F.; O'Connor, B.; Park, T.-E.; Sanchez, H.; Sliz, J.; Sontheimer-Phelps, A.; Swenor, B.

10.1101/569541 — bioengineering — Posted on 2019-03-06

2693 AgarFix: simple and accessible stabilization of challenging single-particle cryo-EM specimens through cross-linking in a matrix of agar

Adamus, K.; Le, S. N.; Elmlund, H.; Boudes, M.; Elmlund, D.

10.1101/569087 — biochemistry — Posted on 2019-03-06

2694 MRI and cognitive scores complement each other to accurately predict Alzheimer’s dementia 2 to 7 years before clinical onset

Zandifar, A.; Fonov, V.; Ducharme, S.; Belleville, S.; Collins, D. L.

10.1101/567867 — neuroscience — Posted on 2019-03-06

2695 The cellular response towards lanthanum is substrate specific and reveals a novel route for glycerol metabolism in Pseudomonas putida KT2440

Wehrmann, M.; Toussaint, M.; Pfannstiel, J.; Billard, P.; Klebensberger, J.

10.1101/567529 — microbiology — Posted on 2019-03-06

2696 Comparison of single nucleotide variants identified by Illumina and Oxford Nanopore technologies in the context of a potential outbreak of Shiga Toxin Producing Escherichia coli.

Dallman, T.; Jenkins, C.; Gharbia, S.; Greig, D.

10.1101/570192 — microbiology — Posted on 2019-03-06

2697 Stiffness and tension gradients of the hair cell’s tip-link complex in the mammalian cochlea

Tobin, M.; Chaiyasitdhi, A.; Michel, V.; Michalski, N.; Martin, P.

10.1101/497222 — biophysics — Posted on 2019-03-06

2698 Marine metabolomics: Measurement of metabolites in seawater by gas-chromatography mass spectrometry

Sogin, E. M.; Puskas, E.; Dubilier, N.; Liebeke, M.

10.1101/528307 — biochemistry — Posted on 2019-03-06

2699 Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines

Asquith, C. R. M.; Fleck, N.; Grundner, C.; Zuercher, W. J.

10.1101/570002 — pharmacology and toxicology — Posted on 2019-03-06

2700 Retrospective inference as a form of bounded rationality, and its beneficial influence on learning

FitzGerald, T. H. B.; Devaux, T.; Penny, W. D.; Bonnici, H.; Adams, R. A.

10.1101/569574 — neuroscience — Posted on 2019-03-06

2701 Excitatory GABAergic signalling is associated with acquired benzodiazepine resistance in status epilepticus

Burman, R. J.; Calin, A.; Codadu, N. K.; Wright, R.; Newey, S. E.; van den Berg, M.; Lee, J. H.; Parrish, R. R.; Wilmshurst, J. M.; Akerman, C. J.; Trevelyan, A. J.; Raimondo, J. V.

10.1101/478594 — neuroscience — Posted on 2019-03-06

2702 Decoding mouse behavior to explain single-trial decisions and their relationship with neural activity.

Weissenberger, Y.; King, A. J.; Dahmen, J. C.

10.1101/567479 — neuroscience — Posted on 2019-03-06

2703 Ancestral persistence of vestibulo-spinal reflexes in axial muscles in humans

Guillaud, E.; Faure, C.; Doat, E.; Bouyer, L.; Guehl, D.; Cazalets, J.-R.

10.1101/564617 — neuroscience — Posted on 2019-03-06

2704 The Evolutionary Dynamics and Fitness Landscape of Clonal Haematopoiesis

Watson, C. J.; Papula, A.; Poon, Y. P. G.; Wong, W. H.; Young, A. L.; Druley, T. E.; Fisher, D. S.; Blundell, J. R.

10.1101/569566 — genomics — Posted on 2019-03-06

2705 Cassava planting material movement and grower behaviour in Zambia: implications for disease management

Szyniszewska, A. M.; Chikoti, P. C.; Tembo, M.; Mulenga, R.; Gilligan, C. A.; van den Bosch, F.; McQuaid, C. F.

10.1101/528851 — epidemiology — Posted on 2019-03-06

2706 Changes in the Biodiversity Intactness Index in tropical and subtropical forest biomes, 2001-2012.

De Palma, A.; Hoskins, A.; Gonzalez, R. E.; Newbold, T.; Sanchez-Ortiz, K.; Ferrier, S.; Purvis, A.

10.1101/311688 — ecology — Posted on 2019-03-06

2707 Embryonic signals perpetuate polar-like trophoblast stem cells and pattern the blastocyst axis.

Frias Aldeguer, J.; Kip, M.; Vivie, J.; Li, L.; Alemany, A.; Korving, J.; Darmis, F.; van Blitterswijk, C.; van Oudenaarden, A.; Geijsen, N.; Rivron, N. C.

10.1101/510362 — developmental biology — Posted on 2019-03-06

2708 Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Kolitsida, P.; Zhou, J.; Rackiewicz, M.; Nolic, V.; Dengjel, J.; Abeliovich, H.

10.1101/513135 — cell biology — Posted on 2019-03-06

2709 HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness Phenotype in Medulloblastoma

Jaeger, M. d. C.; Ghisleni, E. C.; Cardoso, P. S.; Siniglaglia, M.; Falcon, T.; Brunetto, A. T.; Brunetto, A. L.; de Farias, C. B.; Taylor, M. D.; Nor, C.; Ramaswamy, V.; Roesler, R.

10.1101/521393 — cancer biology — Posted on 2019-03-06

2710 Ephemeral states in protein folding under force captured with a novel magnetic tweezers design

Tapia-Rojo, R.; Eckels, E. C.; Fernandez, J. M.

10.1101/310060 — biophysics — Posted on 2019-03-06

2711 ARG-miner: A web platform for crowdsourcing-based curation of antibiotic resistance genes

Argoty, G. A. A.; Guron, G. K.; Garner, E.; Riquelme, M. V.; Heath, L.; Pruden, A.; Vikesland, P.; Zhang, L.

10.1101/274282 — bioinformatics — Posted on 2019-03-06

2712 Report on the spatial spread of defective interfering particles and its role in suppressing infectious particles

Ali, Q.; Ke, R.

10.1101/558932 — bioengineering — Posted on 2019-03-06

2713 A Modification of the Bielschowsky Silver Stain for Alzheimer Neuritic Plaques: Suppression of Artifactual Staining by Pretreatment with Oxidizing Agents

Intorcia, A. J.; Filon, J. R.; Hoffman, B.; Serrano, G. E.; Sue, L. I.; Beach, T. G.

10.1101/570093 — neuroscience — Posted on 2019-03-06

2714 Identifying genetic determinants of complex phenotypes from whole genome sequence data

Long, G. S.; Hussen, M.; Dench, J.; Aris-Brosou, S.

10.1101/181222 — bioinformatics — Posted on 2019-03-06

2715 Bed nucleus of the stria terminalis regulates fear to ambiguous threat signals

Goode, T. D.; Ressler, R. L.; Acca, G. M.; Miles, O.; Maren, S.

10.1101/376228 — neuroscience — Posted on 2019-03-06

2716 Activity-dependent long-term potentiation of electrical synapses in the mammalian thalamus

Fricker, B.; Heckman, E.; Cunningham, P. C.; Haas, J.

10.1101/570101 — neuroscience — Posted on 2019-03-06

2717 CHaRTr: An R toolbox for modeling Choices and Response Times in decision-making tasks

Chandrasekaran, C.; Hawkins, G.

10.1101/570184 — neuroscience — Posted on 2019-03-06

2718 A unified method for rare variant analysis of gene-environment interactions

Lim, E.; Chen, H.; Dupuis, J.; Liu, C.-T.

10.1101/570226 — genetics — Posted on 2019-03-06

2719 7q11.23 Syndromes Reveal BAZ1B as a Master Regulator of the Modern Human Face and Validate the Self-Domestication Hypothesis

Zanella, M.; Vitriolo, A.; Andirko, A.; Martins, P. T.; Sturm, S.; O'Rourke, T.; Laugsch, M.; Malerba, N.; Skaros, A.; Trattaro, S.; Germain, P.-L.; Merla, G.; Rada-Iglesias, A.; Boeckx, C.; Testa, G.

10.1101/570036 — evolutionary biology — Posted on 2019-03-06

2720 An integrated workflow for cross-linking/mass spectrometry

Mendes, M. L.; Fischer, L.; Chen, Z. A.; Barbon, M.; O'Reilly, F. J.; Giese, S.; Bohlke-Schneider, M.; Belsom, A.; Dau, T.; Combe, C. W.; Graham, M.; Eisele, M. R.; Baumeister, W.; Speck, C.; Rappsilber, J.

10.1101/355396 — biochemistry — Posted on 2019-03-06

2721 DUX is a non-essential synchronizer of zygotic genome activation

De Iaco, A.; Verp, S.; Offner, S.; Trono, D.

10.1101/569434 — developmental biology — Posted on 2019-03-06

2722 A hierarchical approach to model decision making: a study in chemotactic behavior of Escherichia coli

Vafadar, S.; Kavousi, K.; Safdari, H.; Kalirad, A.; Sadeghi, M.

10.1101/569277 — systems biology — Posted on 2019-03-06

2723 Th2 cytokine profile in appendicular lavage fluid is compatible with allergy as an etiology for acute appendicitis

Carvalho, N.; Barros, A.; Coelho, H. O.; Moita, C. F.; Neves-Costa, A.; Borges, F. C.; Moita, L. F.; Costa, P.

10.1101/569947 — pathology — Posted on 2019-03-06

2724 Transduction of gluconeogenic enzymes prolongs cone photoreceptor survival and function in models of retinitis pigmentosa

Chinchore, Y.; Begaj, T.; Guillermeir, C.; Steinhauser, M. L.; Punzo, C.; Cepko, C. L.

10.1101/569665 — neuroscience — Posted on 2019-03-06

2725 Decoding P300 Variability using Convolutional Neural Networks

Solon, A. J.; Lawhern, V. J.; Touryan, J.; McDaniel, J. R.; Ries, A. J.; Gordon, S. M.

10.1101/569616 — neuroscience — Posted on 2019-03-06

2726 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth

Galdi, P.; Blesa Cabez, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P.

10.1101/569319 — neuroscience — Posted on 2019-03-06

2727 Machine learning Classification of Dyslexic Children based on EEG Local Network Features

Rezvani, Z.; Zare, M.; Zaric, G.; Bonte, M.; Tijms, J.; van der Molen, M.; Gonzalez, G. F.

10.1101/569996 — neuroscience — Posted on 2019-03-06

2728 Differential requirements of cyclase associated protein (CAP) for actin turnover during the lytic cycle of Toxoplasma gondii

Hunt, A.; Wagener, J.; Kent, R.; Carmeille, R.; Russell, M.; Peddie, C.; Collinson, L.; Heaslip, A.; Ward, G. E.; Treeck, M.

10.1101/569368 — microbiology — Posted on 2019-03-06

2729 Genome-wide association analysis for resistance to infectious pancreatic necrosis virus identifies candidate genes involved in viral replication and immune response in rainbow trout (Oncorhynchus mykiss)

Rodrigues, F.; Flores-Mara, R.; Yoshida, G.; Barria, A.; Jedlicki, A.; Lhorente, J. P.; Reyes, F.; Yanez, J.

10.1101/569632 — genomics — Posted on 2019-03-06

2730 The flickering connectivity system of the north Andean paramos

Flantua, S. G. A.; O'Dea, A.; Onstein, R. E.; Hooghiemstra, H.

10.1101/569681 — ecology — Posted on 2019-03-06

2731 Distinct defense strategies allow different grassland species to cope with root herbivore attack

Herve, M.; Erb, M.

10.1101/569533 — ecology — Posted on 2019-03-06

2732 Asymmetric Division Promotes Therapeutic Resistance In Glioblastoma Stem Cells

Hitomi, M.; Chumakova, A. P.; Silver, D. J.; Knudsen, A. M.; Pontius, W. D.; Murphy, S.; Anand, N.; Kristensen, B. W.; Lathia, J. D.

10.1101/569962 — cancer biology — Posted on 2019-03-06

2733 Network analysis allows to unravel breast cancer molecular features and to identify novel targets

Savino, A.; Avalle, L.; Monteleone, E.; Miglio, I.; Griffa, A.; Accetta, G.; Provero, P.; Poli, V.

10.1101/570051 — cancer biology — Posted on 2019-03-06

2734 Unearthing Regulatory Axes of Breast Cancer circRNAs Networks to Find Novel Targets and Fathom Pivotal Mechanisms

Afzali, F.; Salimi, M.

10.1101/569756 — bioinformatics — Posted on 2019-03-06

2735 Interaction Effects of Apolipoprotein E ε 4 and Cognitive Status on the Functional Connectivity within Default Mode Network in Individuals at Risk of Cognitive Impairments

Lu, H.; Ma, S. L.; Wing, W. C. C.; Wong, S. W. H.; Lam, L. C. W.

10.1101/565812 — neuroscience — Posted on 2019-03-06

2736 Motor fatigability as evoked by repetitive movements results from a gradual breakdown of surround inhibition

Baechinger, M.; Lehner, R.; Thomas, F.; Hanimann, S.; Balsters, J. H.; Wenderoth, N.

10.1101/569608 — neuroscience — Posted on 2019-03-06

2737 Development of high throughput methods for the analysis of anthelmintic resistance allele frequencies in field populations of gastrointestinal nematodes.

Sargison, N. D.; MacLeay, M.; Morrison, A. A.; Bartley, D. J.; Evans, M.; Chaudhry, U.

10.1101/569863 — molecular biology — Posted on 2019-03-06

2738 Afucosylated maternal anti-dengue IgGs are a biomarker for susceptibility to dengue disease in their infants

Thulin, N. K.; Brewer, R. C.; Sherwood, R.; Bournazos, S.; Edwards, K. G.; Ramadoss, N. S.; Taubenberger, J. K.; Memoli, M.; Jagannathan, P.; Zhang, S.; Libraty, D. H.; Wang, T. T.

10.1101/565259 — immunology — Posted on 2019-03-06

2739 β-Caryophyllene Enhances the Transcriptional Upregulation of Cholesterol Biosynthesis in Breast Cancer Cells

Mboge, M. Y.; Ramirez-Mata, A.; Bullock, A.; O'Donnell, R.; Mathias, J.; Davila, J.; Frost, C. J.; Frost, S. C.

10.1101/569558 — cancer biology — Posted on 2019-03-06

2740 Methods for Analyzing Imaging Mass Cytometry Data with Tellurium Probes

Bassan, J.; Nitz, M.

10.1101/567685 — bioinformatics — Posted on 2019-03-06

2741 Wnt7a-releasing synthetic hydrogel enhances local skeletal muscle regeneration and muscle stem cell engraftment

Han, W. M.; Mohiuddin, M.; Anderson, S. E.; Garcia, A. J.; Jang, Y. C.

10.1101/569921 — bioengineering — Posted on 2019-03-06

2742 Xenogeneic regulation of the ClpCP protease of Bacillus subtilis by a phage-encoded adaptor-like protein

Mulvenna, N.; Hantke, I.; Burchell, L.; Nicod, S.; Turgay, K.; Wigneshweraraj, R.

10.1101/569657 — microbiology — Posted on 2019-03-06

2743 Mechanistic characterization of RASGRP1 variants identifies an hnRNP K-regulated transcriptional enhancer contributing to SLE susceptibility

Molineros, J. E.; Singh, B.; Terao, C.; Okada, Y.; Kaplan, J.; McDaniel, B.; Akizuki, S.; Sun, C.; Webb, C.; Looger, L. L.; Nath, S. K.

10.1101/568790 — genetics — Posted on 2019-03-06

2744 RhizoVision Crown: An Integrated Hardware and Software Platform for Root Crown Phenotyping

Seethepalli, A.; Guo, H.; Liu, X.; Griffiths, M.; Almtarfi, H.; Li, Z.; Liu, S.; Zare, A.; Fritschi, F.; Blancaflor, E.; Ma, X.; York, L. M.

10.1101/569707 — plant biology — Posted on 2019-03-06

2745 Emergence of Functional Cortical Patterns of neurons characterize the self-organizing way to cognition in brain.

Gund, J.; Singh, R. K. B.

10.1101/569244 — neuroscience — Posted on 2019-03-06

2746 Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle

Li, X.; Kumar, S.; McDew-White, M.; Haile, M.; Cheeseman, I. H.; Emrich, S.; Button-Simons, K.; Nosten, F.; Kappe, S.; Ferdig, M.; Anderson, T.; Vaughan, A.

10.1101/570085 — evolutionary biology — Posted on 2019-03-06

2747 MetaMLP: A fast word embedding based classifier to profile target gene databases in metagenomic samples

Arango-Argoty, G. A.; Heath, L. S.; Pruden, A.; Vikesland, P.; Zhang, L.

10.1101/569970 — bioinformatics — Posted on 2019-03-06

2748 Genomic landscape of 261 childhood cancer patient-derived xenograft models

10.1101/566455 — genomics — Posted on 2019-03-06

2749 Keeping salamanders off the streets: An assessment of one of the first amphibian road tunnels in the United States 30 years after installation

Hedrick, B.; Vander Linden, A.; Watt, E.; O'Roark, P.; Cordero, S.; Sutherland, C.

10.1101/569426 — ecology — Posted on 2019-03-06

2750 High ribulose-1,5-bisphosphate carboxylase/oxygenase content in northern diatom species

Gerecht, A. C.; Eriksen, G. K.; Uradnikova, M.; Eilertsen, H. C.

10.1101/569285 — ecology — Posted on 2019-03-06

2751 CUT&Tag for efficient epigenomic profiling of small samples and single cells

Kaya-Okur, H. S.; Wu, S. J.; Codomo, C. A.; Pledger, E. S.; Bryson, T. D.; Henikoff, J. G.; Ahmad, K.; Henikoff, S.

10.1101/568915 — genomics — Posted on 2019-03-06

2752 Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Taliun, D.; Harris, D. N.; Kessler, M. D.; Carlson, J.; Szpiech, Z. A.; Torres, R.; Gagliano Taliun, S. A.; Corvelo, A.; Gogarten, S. M.; Min Kang, H.; Pitsillides, A. N.; LeFaive, J.; Lee, S.-b.; Tian, X.; Browning, B. L.; Das, S.; Emde, A.-K.; Clarke, W. E.; Loesch, D. P.; Shetty, A. C.; Blackwell, T. W.; Wong, Q.; Aguet, F.; Albert, C.; Alonso, A.; Ardlie, K. G.; Aslibekyan, S.; Auer, P. L.; Barnard, J.; Barr, R. G.; Becker, L. C.; Beer, R. L.; Benjamin, E. J.; Bielak, L. F.; Blangero, J.; Boehnke, M.; Bowden, D. W.; Brody, J. A.; Burchard, E. G.; Cade, B. E.; Casella, J. F.; Chalazan, B. L

10.1101/563866 — genomics — Posted on 2019-03-06

2753 Demonstration of simultaneous biological sulphate reduction and partial sulphide oxidation in a hybrid linear flow channel reactor

Marais, T. S.; Huddy, R.; Harrison, S. T. L.; van Hille, R.

10.1101/569269 — bioengineering — Posted on 2019-03-06

2754 Chemical screening pipeline for identification of specific plant autophagy modulators

Dauphinee, A. N.; Cardoso, C.; Dalman, K.; Ohlsson, J.; Berglund Fick, S.; Robert, S.; Hicks, G. R.; Bozhkov, P. V.; Minina, E. A.

10.1101/569327 — plant biology — Posted on 2019-03-06

2755 A comparison of DNA stains and staining methods for Agarose Gel Electrophoresis

Hall, A. C.

10.1101/568253 — molecular biology — Posted on 2019-03-06

2756 GSTM1 copy number is not associated with risk of kidney failure in a large cohort

Zhang, Y.; Zafar, W.; Hartzel, D. N.; Williams, M. S.; Tin, A.; Chang, A. R.; Regeneron Genetics Center, ; Lee, M. T. M.

10.1101/567651 — genetics — Posted on 2019-03-06

2757 Back-propagation learning in deep Spike-By-Spike networks

Rotermund, D.; Pawelzik, K. R.

10.1101/569236 — bioinformatics — Posted on 2019-03-06

2758 Robust Hierarchical Density Estimation and Regression for Re-stained Histological Whole Slide Image Co-registration

Jiang, J.; Larson, N.; Prodduturi, N.; Flotte, T.; Hart, S.

10.1101/565564 — bioinformatics — Posted on 2019-03-06

2759 Implicit semantic prediction error can account for N400 effects on articles that do not differ in meaning: A neural network model

Rabovsky, M.

10.1101/569020 — neuroscience — Posted on 2019-03-06

2760 Towards next generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics

Goig, G. A.; Torres-Puente, M.; Mariner Llicer, C.; Villamayor, L. M.; Chiner-Oms, A.; Gil-Brusola, A.; Borras, R.; Comas, I.

10.1101/569384 — microbiology — Posted on 2019-03-06

2761 Notch signaling and taxis mechanims regulate early stage angiogenesis: A mathematical and computational model

Vega, R.; Carretero, M.; Travasso, R. D. M.; Bonilla, L. L.

10.1101/569897 — systems biology — Posted on 2019-03-06

2762 Complex interaction networks of cytokines after transarterial chemotherapy in patients with hepatocellular carcinoma

JEKARL, D. W.; Lee, S.; Kwon, J. H.; Nam, S. W.; Jang, J. W.; Kim, M.; Kim, Y.

10.1101/569939 — immunology — Posted on 2019-03-06

2763 Hydrology-informed metapopulation modeling of liver fluke transmission in the Lawa Lake complex of northeast Thailand

Leon, T. M.; Plermkamon, V.; Kuntiyawichai, K.; Sripa, B.; Spear, R. C.

10.1101/569913 — epidemiology — Posted on 2019-03-06

2764 Determination of glucosinolate contents in Brassica germplasm collections and inter- & intra-leaves distribution pattern using UPLC-MS/MS Multiple Reaction Monitoring scan mode

Assefa, A. D.; Choi, S.; Lee, J.-E.; Sung, J.-S.; Hur, O.-S.; Ro, N.-Y.; Lee, H.-S.; Noh, J.; Hwang, A.; Ko, H.-C.; Chung, Y.-J.; Rhee, J. H.

10.1101/569889 — biochemistry — Posted on 2019-03-06

2765 Assessing introgressive hybridization in roan antelope (Hippotragus equinus): Lessons from South Africa

van Wyk, A. M. L.; Dalton, D. L.; Kotze, A. L.; Grobler, J. P.; Mokgokong, P. S. L.; Kropff, A. S. L.; Jansen van Vuuren, B.

10.1101/569830 — zoology — Posted on 2019-03-06

2766 Saxitoxin and tetrodotoxin bioavailability increases in future oceans

Roggatz, C. C.; Fletcher, N.; Benoit, D. M.; Algar, A. C.; Doroff, A.; Wright, B.; Wollenberg Valero, K. C.; Hardege, J. D.

10.1101/562694 — pharmacology and toxicology — Posted on 2019-03-06

2767 High prevalence of antibiotic resistance in Helicobacter pylori isolates from Iran: importance of functional and mutational analysis of resistance genes and virulence genotyping

Farzi, N.; Yadegar, A.; Asadzadeh Aghdaei, H.; Sadeghi, A.; Zali, M. R.

10.1101/569814 — microbiology — Posted on 2019-03-06

2768 Ciliary Genes arl13b, ahi1 and cc2d2a Differentially Modify Expression of Visual Acuity Phenotypes but do not Enhance Retinal Degeneration due to Mutation of cep290 in Zebrafish

Perkins, B.; Lessieur, E.; Song, P.; Nivar, G.; Piccillo, E.; Fogerty, J.; Rozic, R.

10.1101/569822 — cell biology — Posted on 2019-03-06

2769 An Analytic Platform for the Rapid and Reproducible Annotation of Ventilator Waveform Data

Rehm, G. B.; Kuhn, B. T.; Lieng, M. K.; Cortes-Puch, I.; Nguyen, J.; Guo, E.; Delplanque, J.-P.; Anderson, N. R.; Adams, J. Y.

10.1101/568386 — physiology — Posted on 2019-03-06

2770 Time-series genome-centric analysis unveils bacterial response to operational disturbance in activated sludge

Perez, M. V.; Guerrero, L. D.; Orellana, E.; Figuerola, E. L.; Erijman, L.

10.1101/565770 — microbiology — Posted on 2019-03-06

2771 Integrating Genome-Wide Association and eQTLs Studies Identifies the Genes Associated with Age at Menarche and Age at Natural Menopause

An, Y.; Wang, G.; LV, J.; Qiu, X.

10.1101/569731 — genetics — Posted on 2019-03-06

2772 Impact of pterygium on the ocular surface and meibomian glands

Wanzeler, A.; Barbosa, I. A. F.; Duarte, B.; Barbosa, E. B.; Borges, D. A.; Alves, M.

10.1101/569772 — epidemiology — Posted on 2019-03-06

2773 Non-linear dendritic integration in frontal circuits shapes sensory discrimination in rodents

Aime, M.; Augusto, E.; Kouskoff, V.; Martin, C.; Humeau, Y.; Chenouard, N.; Gambino, F.

10.1101/569137 — neuroscience — Posted on 2019-03-06

2774 Quantitative multiplexed ChIP reveals global alterations that shape promoter bivalency in ground state embryonic stem cells

Kumar, B.; Elsässer, S. J.

10.1101/557082 — molecular biology — Posted on 2019-03-06

2775 Elucidation of the viral disassembly switch of tobacco mosaic virus

Weis, F.; Beckers, M.; von der Hocht, I.; Sachse, C.

10.1101/569178 — molecular biology — Posted on 2019-03-06

2776 How to make more from exposure data? An integrated machine learning pipeline to predict pathogen exposure

Fountain-Jones, N.; Machado, G.; Carver, S.; Packer, C.; Mendoza, M.; Craft, M. E.

10.1101/569012 — ecology — Posted on 2019-03-06

2777 Base pairing interactions between substrate RNA and H/ACA guide RNA modulate the kinetics of pseudouridylation, but not the affinity of substrate binding by H/ACA small nucleolar Ribonucleoproteins

Kelly, E. K.; Kothe, U.

10.1101/569061 — biochemistry — Posted on 2019-03-06

2778 A common tag nucleotide variant in MMP7 promoter increases risk for hypertension via enhanced interactions with CREB transcription factor

Subramanian, L.; Maghajothi, S.; Singh, M.; Kesh, K.; Ananthamohan, K.; Sharma, S.; Khullar, M.; Victor, S. M.; Swarnakar, S.; Asthana, S.; Mullasari, A. S.; Mahapatra, N. R.

10.1101/568774 — genetics — Posted on 2019-03-06

2779 Large-scale kinetic metabolic models of Pseudomonas putida for a consistent design of metabolic engineering strategies

Tokic, M.; Miskovic, L.; Hatzimanikatis, V.

10.1101/569152 — systems biology — Posted on 2019-03-06

2780 Absence of entourage: Terpenoids commonly found in Cannabis sativa do not modulate the functional activity of Δ9-THC at human CB1 and CB2 receptors

Santiago, M. J.; Sachdev, S.; Arnold, J. C.; McGregor, I. S.; Connor, M.

10.1101/569079 — pharmacology and toxicology — Posted on 2019-03-06

2781 Urinary biomarker and histopathological evaluation of vancomycin and piperacillin-tazobactam nephrotoxicity in comparison with vancomycin in a rat model and a confirmatory cellular model

Pais, G. M.; Liu, J.; Avedissian, S. N.; Xanthos, T.; Chalkias, A.; d'Aloja, E.; Locci, E.; Gilchrist, A.; Prozialeck, W. C.; Rhodes, N.; Lodise, T. P.; Fitzgerald, J. C.; Downes, K.; Zuppa, A.; Scheetz, M. H.

10.1101/568907 — pharmacology and toxicology — Posted on 2019-03-06

2782 Visual and auditory information shed light on savings mechanisms

White, O.; Barbiero, M.; Marechal, Q.; Orban de Xivry, J.-J.

10.1101/569186 — neuroscience — Posted on 2019-03-06

2783 Neural Correlates of Cognition in Primary Visual versus Neighboring Posterior Cortices during Visual Evidence-Accumulation-based Navigation

Koay, S. A.; Thiberge, S. Y.; Brody, C.; Tank, D. W.

10.1101/568766 — neuroscience — Posted on 2019-03-06

2784 Genetic Polymorphisms and Molecular Mechanisms Mediating Oncolytic Potency of Reovirus Strains

Mohamed, A.; Clements, D. R.; Konda, P.; Gujar, S. A.; Lee, P.; Smiley, J. R.; Shmulevitz, M.

10.1101/569301 — microbiology — Posted on 2019-03-06

2785 Identification of Genes Regulating Cell Death in Staphylococcus aureus

Yee, R.; Feng, J.; Wang, J.; Chen, J.; ZHANG, Y.

10.1101/569053 — microbiology — Posted on 2019-03-06

2786 Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

Forsberg, K. J.; Bhatt, I. V.; Schmidtke, D. T.; Stoddard, B. L.; Kaiser, B. K.; Malik, H. S.

10.1101/569095 — microbiology — Posted on 2019-03-06

2787 Gut feelings begin in childhood: how the gut metagenome links to early environment, caregiving, and behavior

Flannery, J.; Stagaman, K.; Burns, A. R.; Hickey, R. J.; Roos, L. E.; Giuliano, R. J.; Fisher, P.; Sharpton, T.

10.1101/568717 — microbiology — Posted on 2019-03-06

2788 A topological data analysis based classification method for multiple measurement

Riihimaki, H.; Chacholski, W.; Theorell, J.; Hillert, J.; Ramanujam, R.

10.1101/569210 — bioinformatics — Posted on 2019-03-06

2789 Perturbation biology links temporal protein changes to drug responses in a melanoma cell line

Nyman, E.; Stein, R. R.; Jing, X.; Wang, W.; Marks, B.; Zervantonakis, I. K.; Korkut, A.; Gauthier, N. P.; Sander, C.

10.1101/568758 — systems biology — Posted on 2019-03-06

2790 A streamlined protocol and analysis pipeline for CUT&RUN chromatin profiling

Meers, M. P.; Bryson, T. D.; Henikoff, S.

10.1101/569129 — molecular biology — Posted on 2019-03-06

2791 Chromosome-wide co-fluctuation of stochastic gene expression in mammalian cells

Sun, M.; Zhang, J. G.

10.1101/569004 — genomics — Posted on 2019-03-06

2792 Geography Shapes the Population Genomics of Salmonella enterica Dublin

Fenske, G.; Thachil, A. J.; McDonough, P. L.; Glaser, A. L.; Scaria, J.

10.1101/569145 — genomics — Posted on 2019-03-06

2793 A Role for Gαz in regulating seizure susceptibility

Hultman, R.; Boms, O.; Mague, S. D.; Hughes, D.; Nadler, V.; Dzirasa, K.; Casey, P. J.

10.1101/567628 — neuroscience — Posted on 2019-03-06

2794 AgarFix: simple and accessible stabilization of challenging single-particle cryo-EM specimens through cross-linking in a matrix of agar

Adamus, K.; Boudes, M.; Le, S. N.; Elmlund, H.; Elmlund, D.

10.1101/569087 — biochemistry — Posted on 2019-03-06

2795 What the odor is not: Estimation by elimination

Singh, V.; Tchernookov, M.; Balasubramanian, V.

10.1101/568626 — neuroscience — Posted on 2019-03-06

2796 Mutation profiling of both cfDNAs and CTCs in gynecological cancer patients

Lee, S.-Y.; Chae, D.-k.; An, J.; Jung, S.; Bhak, J.; Kim, B. C.; Cho, D.-H.

10.1101/566786 — genetics — Posted on 2019-03-06

2797 On the importance of accounting for intraspecific genomic relatedness in multi-species studies

Joly, S.; Flynn, D. F. B.; Wolkovich, E.

10.1101/321927 — ecology — Posted on 2019-03-06

2798 Homotypic and heterotypic trans-assembly of human Rab-family small GTPases in reconstituted membrane tethering

Segawa, K.; Tamura, N.; Mima, J.

10.1101/544379 — cell biology — Posted on 2019-03-06

2799 Moments reconstruction and local dynamic range compression of high order Superresolution Optical Fluctuation Imaging

Yi, X.; Son, S.; Ando, R.; Miyawaki, A.; Weiss, S.

10.1101/500819 — bioengineering — Posted on 2019-03-06

2800 Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.

Basbous, J.; Aze, A.; Chaloin, L.; Lebdy, R.; Hodroj, D.; Ribeyre, C.; Larroque, M.; Shepard, C.; Kim, B.; Pruvost, A.; Moreaux, J.; Maiorano, D.; Mechali, M.; Constantinou, A.

10.1101/420893 — cancer biology — Posted on 2019-03-05

2801 Contribution of Apical and Basal Dendrites of L2/3 Pyramidal Neurons to Orientation Encoding in Mouse V1

Park, J.; Papoutsi, A.; Ash, R. T.; Marin, M. A.; Poirazi, P.; Smirnakis, S. M.

10.1101/566588 — neuroscience — Posted on 2019-03-05

2802 Shared neural underpinnings of multisensory integration and trial-by-trial perceptual recalibration

Park, H.; Kayser, C.

10.1101/566927 — neuroscience — Posted on 2019-03-05

2803 Improved HLA-based prediction of coeliac disease identifies two novel HLA risk modifiers, DQ6.2 and DQ7.3

Erlichster, M.; Bedo, J.; Skafidas, E.; Kwan, P.; Kowalczyk, A.; Goudey, B.

10.1101/561308 — genetics — Posted on 2019-03-05

2804 A Signaling Network based Computational Model to Uncover Loop as the Novel Molecular Mechanisms for Medulloblastoma

Xu, J.; Li, F.

10.1101/561076 — bioinformatics — Posted on 2019-03-05

2805 Somatostatin-Expressing Interneurons Co-Release GABA and Glutamate onto Different Postsynaptic Targets in the Striatum.

Cattaneo, S.; Zaghi, M.; Ripamonti, M.; Bedogni, F.; Sessa, A.; Taverna, S.

10.1101/566984 — neuroscience — Posted on 2019-03-05

2806 Learning what is irrelevant or relevant: Expectations facilitate distractor inhibition and target facilitation through distinct neural mechanisms

van Moorselaar, D.; Slagter, H. A.

10.1101/565069 — neuroscience — Posted on 2019-03-05

2807 Functional arrays of human pluripotent stem cell-derived cardiac microtissues

Thavandiran, N.; Hale, C.; Blit, P.; Sandberg, M. L.; McElvain, M. E.; Gagliardi, M.; Sun, B.; Witty, A.; Graham, G.; McIntosh, M.; Bakooshli, M. A.; Le, H.; Ostblom, J.; McEwen, S.; Chau, E.; Prowse, A.; Fernandes, I.; Gilbert, P. M.; Keller, G.; Tagari, P.; Xu, H.; Radisic, M.; Zandstra, P.

10.1101/566059 — bioengineering — Posted on 2019-03-05

2808 Genetic, epigenetic and pharmacological influences modulating tissue specific regulation of the cannabinoid receptor -1 (CB1) gene; implications for cannabinoid pharmacogenetics.

Hay, E. A.; Cowie, P. D.; McEwan, A. R.; Wilson, D.; Ross, R.; Barrett, P.; Pertwee, R. G.; MacKenzie, A.

10.1101/544585 — genetics — Posted on 2019-03-05

2809 A reformulation of the selection ratio shed light on resource selection functions and leads to a unified framework for habitat selection studies.

Chamaille-Jammes, S.

10.1101/565838 — ecology — Posted on 2019-03-05

2810 Lytic bacteriophage have diverse indirect effects in a synthetic cross-feeding community

Fazzino, L.; Anisman, J.; Chacon, J. M.; Heineman, R. H.; Harcombe, W. R.

10.1101/560037 — systems biology — Posted on 2019-03-05

2811 Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction

Talkish, J.; Igel, H.; Hunter, O.; Horner, S. W.; Jeffery, N. N.; Leach, J. R.; Jenkins, J. L.; Kielkopf, C. L.; Ares, M.

10.1101/534347 — molecular biology — Posted on 2019-03-05

2812 HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

Asquith, M.; Sternes, P. R.; Costello, M.-E.; Karstens, L.; Diamond, S.; Martin, T. M.; Spector, T. D.; le Cao, K.-A.; Rosenbaum, J. T.; Brown, M. A.

10.1101/517813 — microbiology — Posted on 2019-03-05

2813 High-throughput single-particle tracking reveals nested membrane nanodomain organization that dictates Ras diffusion and trafficking

Lee, Y.; Phelps, C.; Huang, T.; Mostofian, B.; Wu, L.; Zhang, Y.; Chang, Y. H.; Stork, P. J. S.; Gray, J. W.; Zuckerman, D. M.; Nan, X.

10.1101/552075 — biophysics — Posted on 2019-03-05

2814 HABIT - a webserver for interactive T cell neoepitope discovery

Martins, J.; Magalhaes, C.; Vieira, V.; Rocha, M.; Osorio, N. S. S.

10.1101/535716 — bioinformatics — Posted on 2019-03-05

2815 Engineered Enzymes that Retain and Regenerate their Cofactors Enable Continuous-Flow Biocatalysis

Hartley, C. J.; Williams, C. C.; Scoble, J. A.; Churches, Q. I.; French, N. G.; Nebl, T.; Coia, G.; Warden, A. C.; Simpson, G.; Frazer, A.; North, A.; Nixon Jensen, C.; Turner, N. J.; Scott, C.

10.1101/568972 — synthetic biology — Posted on 2019-03-05

2816 Adapterama III: Quadruple-indexed, double/triple-enzyme RADseq libraries (2RAD/3RAD)

Bayona-Vasquez, N. J.; Glenn, T. C.; Kieran, T. J.; Pierson, T. W.; Hoffberg, S. L.; Scott, P. A.; Bentley, K. E.; Finger, J. W.; Louha, S.; Troendle, N.; Diaz-Jaimes, P.; Mauricio, R.; Faircloth, B. C.

10.1101/205799 — genomics — Posted on 2019-03-05

2817 Interaction of Hippocampal Ripples and Cortical Slow Waves Leads to Coordinated Large-Scale Sleep Rhythm

Sanda, P.; Malerba, P.; Jiang, X.; Krishnan, G.; Cash, S.; Halgren, E.; Bazhenov, M.

10.1101/568881 — neuroscience — Posted on 2019-03-05

2818 α-integrins dictate distinct modes of type IV collagen recruitment to basement membranes

Jayadev, R.; Chi, Q.; Keeley, D.; Hastie, E.; Sherwood, D.

10.1101/568964 — cell biology — Posted on 2019-03-05

2819 CA1 pyramidal cells organize an episode by segmented and ordered events

Sun, C.; Yang, W.; Martin, J.; Tonegawa, S.

10.1101/565689 — neuroscience — Posted on 2019-03-05

2820 Testing the role of cognitive inhibition in physical endurance using high-definition transcranial direct current stimulation over the prefrontal cortex.

Denis, G.; Zory, R.; Radel, R.

10.1101/566901 — neuroscience — Posted on 2019-03-05

2821 Afferent-efferent connectivity between auditory brainstem and cortex accounts for poorer speech-in-noise comprehension in older adults

Bidelman, G. M.; Price, C. N.; Shen, D.; Arnott, S.; Alain, C.

10.1101/568840 — neuroscience — Posted on 2019-03-05

2822 Auditory sensory memory span for duration is severely curtailed in females with Rett Syndrome.

Brima, T. J.; Molholm, S.; Molloy, C. J.; Sysoeva, O. V.; Nicholas, E.; Djukic, A.; Freedman, E.; Foxe, J. J.

10.1101/568832 — neuroscience — Posted on 2019-03-05

2823 Temperature accounts for the biodiversity of a hyperdiverse group of insects in urban Los Angeles

McGlynn, T. P.; Meineke, E. K.; Bahlai, C. A.; Li, E.; Hartop, E. A.; Adams, B. J.; Brown, B. V.

10.1101/568212 — ecology — Posted on 2019-03-05

2824 Analysis of single nucleotide variants in CRISPR-Cas9 edited zebrafish embryos shows no evidence of off-target inflation

Katsanis, N.; Mooney, M.; Davis, E. E.

10.1101/568642 — developmental biology — Posted on 2019-03-05

2825 In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex which supports oogenesis

Guioli, S.; Zhao, D.; Nandi, S.; Clinton, M.; Lovell-Badge, R.

10.1101/568691 — developmental biology — Posted on 2019-03-05

2826 A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells

Mboge, M. Y.; Chen, Z.; Khokhar, D.; Wolff, A.; Ai, L.; Heldermon, C. D.; Boxdag, M.; Carta, F.; Supuran, C. T.; Brown, K. D.; McKenna, R.; Frost, C. J.; Frost, S. C.

10.1101/505644 — cancer biology — Posted on 2019-03-05

2827 Mapping the 3D genome through high speed single-molecule tracking of functional transcription factors in single living cells

Wollman, A.; Hedlund, E.; Shashkova, S.; Leake, M.

10.1101/568675 — biophysics — Posted on 2019-03-05

2828 Effects of lipid composition on membrane distribution and permeability of natural quinones

Teixeira, M. H.; Arantes, G. M.

10.1101/568816 — biophysics — Posted on 2019-03-05

2829 Pacing behaviour in laboratory macaques is an unreliable indicator of acute stress.

Poirier, C.; Oliver, C. J.; Flecknell, P.; Bateson, M.

10.1101/568378 — animal behavior and cognition — Posted on 2019-03-05

2830 Single-organelle quantification reveals the stoichiometric and structural variability of carboxysomes dependent on the environment

Sun, Y.; Wollman, A.; Huang, F.; Leake, M. C.; Liu, L.

10.1101/568238 — biophysics — Posted on 2019-03-05

2831 Dynamic neuronal activation of a distributed cortico-basal ganglia-thalamus loop in learning a delayed sensorimotor task

Gu, X.; Li, C. T.

10.1101/568055 — neuroscience — Posted on 2019-03-05

2832 The caudate nucleus contributes causally to decisions that combine noisy visual evidence and reward context

Doi, T.; Fan, Y.; Gold, J. I.; Ding, L.

10.1101/568733 — neuroscience — Posted on 2019-03-05

2833 Postural representations of the hand in primate sensorimotor cortex

Goodman, J. M.; Tabot, G. A.; Lee, A. S.; Suresh, A. K.; Rajan, A. T.; Hatsopoulos, N. G.; Bensmaia, S. J.

10.1101/566539 — neuroscience — Posted on 2019-03-05

2834 Effect of task and attention on neural tracking of speech

Vanthornhout, J.; Decruy, L.; Francart, T.

10.1101/568204 — neuroscience — Posted on 2019-03-05

2835 The Trichoplax microbiome: the simplest animal lives in an intimate symbiosis with two intracellular bacteria

Gruber-Vodicka, H. R.; Leisch, N.; Kleiner, M.; Hinzke, T.; Liebeke, M.; McFall-Ngai, M.; Hadfield, M. G.; Dubilier, N.

10.1101/568287 — microbiology — Posted on 2019-03-05

2836 Single cell transcriptomics identifies immunologic priming related to extra corporeal life support survival.

Kort, E. J.; Weiland, M.; Grins, E.; Eugster, E.; Milliron, H.-y.; Kelty, C.; Shrestha, N. M.; Timek, T.; Leacche, M.; Fitch, S.; Boeve, T.; Marco, G.; Dickinson, M.; Wilton, P.; Jovinge, S.

10.1101/568659 — genomics — Posted on 2019-03-05

2837 Is it reasonable to use of a kinship matrix for best linear unbiased prediction?

Kim, B.

10.1101/568782 — genetics — Posted on 2019-03-05

2838 A cis-regulatory change underlying the motor neuron-specific loss of terminal selector gene expression in immotile tunicate larvae

Lowe, E. K.; Racioppi, C.; Peyrieras, N.; Ristoratore, F.; Christiaen, L.; Swalla, B. J.; Stolfi, A.

10.1101/567719 — evolutionary biology — Posted on 2019-03-05

2839 Proteomic profiling of the oncogenic septin 9 reveals isoform-specific interactions in breast cancer cells

Devlin, L.; Perkins, G.; Bowen, J. R.; Montagna, C.; Spiliotis, E. T.

10.1101/566513 — cell biology — Posted on 2019-03-05

2840 Molecular model of the nuclear pore complex reveals a thermoreversible FG-network with distinct territories occupied by different FG motifs

Huang, K.; Tagliazucchi, M.; Park, S. H.; Rabin, Y.; Szleifer, I.

10.1101/568865 — cell biology — Posted on 2019-03-05

2841 Stalk Lodging: A Portable Device for Phenotyping Stalk Bending Strength of Maize and Sorghum

Cook, D. D.; de la Chapelle, W.; Lin, T.-C.; Lee, S. Y.; Sun, W.; Robertson, D. J.

10.1101/567578 — bioengineering — Posted on 2019-03-05

2842 Early changes in the urine proteome in a rat liver tumor model

Yameng, Z.; Yufei, G.; Youhe, G.

10.1101/568246 — biochemistry — Posted on 2019-03-05

2843 Future ocean warming may prove beneficial for the northern population of European seabass, but ocean acidification does not

Howald, S.; Cominassi, L.; Le Bayon, N.; Claireaux, G.; Mark, F. C.

10.1101/568428 — physiology — Posted on 2019-03-05

2844 Loss of one Engrailed1 allele enhances induced α-synucleinopathy

Chatterjee, D.; Saiz Sanchez, D.; Quansah, E.; Rey, N. L.; George, S.; Becker, K.; Madaj, Z.; Steiner, J. A.; Ma, J.; Escobar Galvis, M. L.; Kordower, J. H.; Brundin, P.

10.1101/530915 — neuroscience — Posted on 2019-03-05

2845 Embryonic signals perpetuate polar-like trophoblast stem cells and pattern the blastocyst axis.

Frias Aldeguer, J.; Kip, M.; Vivie, J.; Li, L.; Alemany, A.; Korving, J.; Darmis, F.; van Blitterswijk, C.; van Oudenaarden, A.; Geijsen, N.; Rivron, N. C.

10.1101/510362 — developmental biology — Posted on 2019-03-05

2846 Thiostrepton hijacks pyoverdine receptors to inhibit growth of Pseudomonas aeruginosa

Ranieri, M. R. M.; Chan, D. C. K.; Yaeger, L. N.; Rudolph, M.; Kerabalas-Pittman, S.; Abdo, H.; Chee, J.; Harvey, H.; Nguyen, U.; Burrows, L. L.

10.1101/567990 — microbiology — Posted on 2019-03-05

2847 Genomic investigation reveals contaminated detergent as the source of an ESBL-producing Klebsiella michiganensis outbreak in a neonatal unit

Chapman, P.; Forde, B.; Roberts, L. W.; Bergh, H.; Vasey, D.; Jennison, A. V.; Moss, S.; Paterson, D. L.; Beatson, S. A.; Harris, P. N. A.

10.1101/568154 — microbiology — Posted on 2019-03-05

2848 Low Mutational Load Allows for High Mutation Rate Variation in Gut Commensal Bacteria

Ramiro, R. S.; Durao, P.; Bank, C.; Gordo, I.

10.1101/568709 — evolutionary biology — Posted on 2019-03-05

2849 A reformulation of the selection ratio shed light on resource selection functions and leads to a unified framework for habitat selection studies.

Chamaille-Jammes, S.

10.1101/565838 — ecology — Posted on 2019-03-05

2850 The restoration species pool for restoring tropical landscapes: assessment of the largest Brazilian supply chain

Vidal, C. Y.; Naves, R.; Viani, R. A. G.; Rodrigues, R. R.

10.1101/568873 — ecology — Posted on 2019-03-05

2851 The expendable male hypothesis

Mattison, S.; Quinlan, R. J.; Hare, D.

10.1101/473942 — animal behavior and cognition — Posted on 2019-03-05

2852 Production of nonnatural straight chain amino acid 6-aminocaproate via an artificial recursive carbon-chain-extension cycle

Cheng, J.; Song, T.; Zhou, X.; Torrens-Spence, M. P.; Wang, D.; Weng, J.-K.; Wang, Q.

10.1101/568121 — synthetic biology — Posted on 2019-03-05

2853 Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis

Hsiao, C. J.; Tung, P.; Blischak, J. D.; Burnett, J.; Barr, K.; Dey, K. K.; Stephens, M.; Gilad, Y.

10.1101/526848 — genomics — Posted on 2019-03-05

2854 RAxML-NG: A fast, scalable, and user-friendly tool for maximum likelihood phylogenetic inference

Kozlov, A.; Darriba, D.; Flouri, T.; Morel, B.; Stamatakis, A.

10.1101/447110 — bioinformatics — Posted on 2019-03-05

2855 A Comparison of Non-human Primate and Deep Reinforcement Learning Agent Performance in a Virtual Pursuit-Avoidance Task

Willke, T. L.; Yoo, S. B. M.; Capota, M.; Musslick, S.; Hayden, B. Y.; Cohen, J. D.

10.1101/567545 — neuroscience — Posted on 2019-03-05

2856 Solving High-Resolution Forward Problems for Extra- and Intracranial Neurophysiological Recordings Using Boundary Element Fast Multipole Method

Makarov, S. N.; Hämäläinen, M.; Okada, Y.; Noetscher, G.; Ahveninen, J.; Nummenmaa, A.

10.1101/567933 — neuroscience — Posted on 2019-03-05

2857 Corrective muscle activity reveals subject-specific sensorimotor recalibration.

Iturralde, P. A.; Torres-Oviedo, G.

10.1101/372359 — neuroscience — Posted on 2019-03-05

2858 RexAB is essential for the mutagenic repair of Staphylococcus aureus DNA damage caused by co-trimoxazole

Clarke, R. S.; Bruderer, M. S.; Ha, K. P.; Edwards, A. M.

10.1101/568196 — microbiology — Posted on 2019-03-05

2859 Stress-induced TFIIIC binding to Alu elements controls gene expression via chromatin looping and histone acetylation

Ferrari, R.; Llobet Cucalon, L. I.; Di Vona, C.; Le Dilly, F.; Vidal, E.; Lioutas, A.; Oliete, J. Q.; Jochem, L.; Cutts, E.; Dieci, G.; Alessandro, V.; Teichmann, M.; de la Luna, S.; Beato, M.

10.1101/455733 — genomics — Posted on 2019-03-05

2860 Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies

Waterhouse, R. M.; Aganezov, S.; Anselmetti, Y.; Lee, J.; Ruzzante, L.; Reijnders, M. J.; Feron, R.; Berard, S.; George, P.; Hahn, M. W.; Howell, P. I.; Kamali, M.; Koren, S.; Lawson, D.; Maslen, G.; Peery, A.; Phillippy, A. M.; Sharakhova, M. V.; Tannier, E.; Unger, M. F.; Zhang, S. V.; Alekseyev, M. A.; Besansky, N. J.; Chauve, C.; Emrich, S. J.; Sharakhov, I. V.

10.1101/434670 — genomics — Posted on 2019-03-05

2861 Amelioration of Brain Histone Methylopathies by Balancing a Writer-Eraser Duo KMT2A-KDM5C

Vallianatos, C. N.; Raines, B.; Porter, R. S.; Wu, M.; Garay, P. M.; Collette, K. M.; Seo, Y. A.; Dou, Y.; Keegan, K.; Tronson, N.; Iwase, S.

10.1101/567917 — genetics — Posted on 2019-03-05

2862 Translational products encoded by novel ORFs may form protein-like structures and have biological functions

Erady, C.; Chong, D.; Meena, N.; Puntambekar, S.; Chauhan, R.; Umrania, Y.; Andreani, A.; Nel, J.; Wayland, M.; Pina, C.; Lilley, K. S.; Prabakaran, S.

10.1101/567800 — genetics — Posted on 2019-03-05

2863 FST and the triangle inequality for biallelic markers

Arbisser, I. M.; Rosenberg, N. A.

10.1101/567743 — evolutionary biology — Posted on 2019-03-05

2864 Genetic drift in range expansions is very sensitive to density feedback in dispersal and growth

Birzu, G.; Matin, S.; Hallatschek, O.; Korolev, K.

10.1101/565986 — evolutionary biology — Posted on 2019-03-05

2865 Allostery in oligomeric receptor models

Conradi Smith, G. D.

10.1101/330571 — biophysics — Posted on 2019-03-05

2866 ARBoR: An Identity and Security Solution for Clinical Reporting

Venner, E.; Murugan, M.; Hale, W.; Jones, J.; Lu, S.; Yi, V.; Gibbs, R. A.

10.1101/567875 — bioinformatics — Posted on 2019-03-05

2867 An engineered monomer binding-protein for α-synucleinefficiently inhibits the proliferation of amyloid fibrils

Agerschou, E. D.; Saridaki, T.; Flagmeier, P.; Galvagnion, C.; Komnig, D.; Nagpal, A.; Gasterich, N.; Heid, L.; Prasad, V.; Shaykhalishahi, H.; Voigt, A.; Willbold, D.; Dobson, C. M.; Falkenburger, B. H.; Hoyer, W.; Buell, A. K.

10.1101/568501 — bioengineering — Posted on 2019-03-05

2868 Network organization of antibody interactions in sequence and structure space: the RADARS model

Prechl, J.

10.1101/438804 — immunology — Posted on 2019-03-05

2869 Evolutionary changes of an intestinal Lactobacillus reuteri during probiotic manufacture

Lopez, L.; Cardenas, P. A.; Prado, M. B.; Trueba, G.

10.1101/567974 — evolutionary biology — Posted on 2019-03-05

2870 Mapping the human subcortical auditory system using histology, post mortem MRI and in vivo MRI at 7T

Sitek, K. R.; Gulban, O. F.; Calabrese, E.; Johnson, G. A.; Ghosh, S. S.; de Martino, F.

10.1101/568139 — neuroscience — Posted on 2019-03-05

2871 Risk of multiple primary cancer diagnosis over age in families of Li-Fraumeni syndrome: a single institution perspective

Shin, S. J.; Dodd, E. B.; Gao, F.; Bojadzieva, J.; Chen, J.; Kong, X.; Amos, C.; Ning, J.; Strong, L. C.; Wang, W.

10.1101/567693 — genetics — Posted on 2019-03-05

2872 Dispersal limitation and stage-specific local filtering processes vary with climate across a network of alpine grasslands

Guittar, J.; Goldberg, D.; Klanderud, K.; Berge, A.; Boixaderas, M. R.; Meineri, E.; Topper, J.; Vandvik, V.

10.1101/567586 — ecology — Posted on 2019-03-05

2873 Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.

Basbous, J.; Aze, A.; Chaloin, L.; Lebdy, R.; Hodroj, D.; Ribeyre, C.; Larroque, M.; Shepard, C.; Kim, B.; Pruvost, A.; Moreaux, J.; Maiorano, D.; Mechali, M.; Constantinou, A.

10.1101/420893 — cancer biology — Posted on 2019-03-05

2874 Synthetic lethality screening reveals FDA-approved drugs that overcome ATP7B-mediated tolerance of tumor cells to cisplatin

Mariniello, M.; Petruzzelli, R.; Wanderlingh, L.; La Montagna, R.; Carissimo, A.; Pane, F.; Amoresano, A.; Medina, D.; Polishchuk, R.

10.1101/568535 — cancer biology — Posted on 2019-03-05

2875 Clustering co-abundant genes identifies components of the gut microbiome that are reproducibly associated with colorectal cancer and inflammatory bowel disease

Minot, S. S.; Willis, A. D.

10.1101/567818 — bioinformatics — Posted on 2019-03-05

2876 Metabolic Cost of Rapid Adaptation of Single Yeast Cells Under Unforeseen Challenge

Woronoff, G.; Nghe, P.; Baudry, J.; Boitard, L.; Braun, E.; Griffiths, A. D.; Bibette, J.

10.1101/564419 — systems biology — Posted on 2019-03-05

2877 HILPDA uncouples lipid storage in adipose tissue macrophages from inflammation and metabolic dysregulation

van Dierendonck, X. A. M. H.; de la Rosa Rodriguez, M. A.; Georgiadi, A.; Mattijssen, F.; Dijk, W.; van Weeghel, M.; Singh, R.; Borst, J. W.; Stienstra, R.; Kersten, S.

10.1101/566802 — physiology — Posted on 2019-03-05

2878 Mechanisms involved in follistatin-induced increased insulin action in skeletal muscle

Han, X.; Moller, L. L. V.; De Groote, E.; Bojsen-Moller, K. K. N.; Davey, J.; Henriquez-Olguin, C.; Li, Z.; Knudsen, J. R.; Jensen, T. E.; Madsbad, S.; Gregorevic, P.; Richter, E. A.; Sylow, L.

10.1101/568097 — physiology — Posted on 2019-03-05

2879 Shared resources between visual attention and visual working memory are allocated through rhythmic sampling

Balestrieri, E.; Ronconi, L.; Melcher, D. P.

10.1101/567602 — neuroscience — Posted on 2019-03-05

2880 Unexpected higher resilience to distraction during visual working memory in schizophrenia

Zhao, Y.; Ran, X.; Zhang, L.; Zhang, R.; Ku, Y.

10.1101/567859 — neuroscience — Posted on 2019-03-05

2881 Looking forward does not mean forgetting about the past: ERP evidence for the interplay of predictive coding and interference during language processing

Schoknecht, P.; Roehm, D.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.

10.1101/567560 — neuroscience — Posted on 2019-03-05

2882 Multiple constrained minimum variance beamformer (MCMV) performance in connectivity analyses

Nunes, A. N.; Moiseev, A.; Kozhemiako, N.; Cheung, T.; Ribary, U.; Doesburg, S.

10.1101/567768 — neuroscience — Posted on 2019-03-05

2883 Non-Invasive Assays of Cochlear Synaptopathy -- Candidates and Considerations

Bharadwaj, H. M.; Mai, A. R.; Simpson, J. M.; Choi, I.; Heinz, M. G.; Shinn-Cunningham, B. G.

10.1101/565655 — neuroscience — Posted on 2019-03-05

2884 What the odor is not: Estimation by elimination

Singh, V.; Tchernookov, M.; Balasubramanian, V.

10.1101/568626 — neuroscience — Posted on 2019-03-05

2885 Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank

Nobis, L.; Manohar, S. G.; Smith, S. M.; Alfaro Almagro, F.; Jenkinson, M.; Mackay, C. E.; Husain, M.

10.1101/562678 — neuroscience — Posted on 2019-03-05

2886 MRI and cognitive scores complement each other to accurately predict Alzheimer’s dementia 2 to 7 years before clinical onset

Zandifar, A.; Fonov, V.; Ducharme, S.; Belleville, S.; Collins, D. L.

10.1101/567867 — neuroscience — Posted on 2019-03-05

2887 Quantifying the efficiency and biases of forest Saccharomyces sampling strategies

Boynton, P. J.; Kowallik, V.; Landermann, D.; Stukenbrock, E. H.

10.1101/559724 — microbiology — Posted on 2019-03-05

2888 HSV-1 single cell analysis reveals anti-viral and developmental programs activation in distinct sub-populations

Drayman, N.; Patel, P.; Vistain, L.; Tay, S.

10.1101/566489 — microbiology — Posted on 2019-03-05

2889 Pacbio sequencing reveals identical organelle genomes between American cranberry (Vaccinium macrocarpon Ait.) and a wild relative

Diaz-Garcia, L.; Rodriguez-Bonilla, L.; Smith, T.; Zalapa, J.

10.1101/567925 — genomics — Posted on 2019-03-05

2890 On the cross-population portability of gene expression prediction models

10.1101/552042 — genomics — Posted on 2019-03-05

2891 Adapterama I: Universal stubs and primers for 384 unique dual-indexed or 147,456 combinatorially-indexed Illumina libraries (iTru & iNext)

Glenn, T. C.; Nilsen, R. A.; Kieran, T. J.; Sanders, J. G.; Bayona-Vasquez, N. J.; Finger, J. W.; Pierson, T. W.; Bentley, K. E.; Hoffberg, S. L.; Louha, S.; Garcia-De-Leon, F. J.; Angel del Rio Portilla, M.; Reed, K. D.; Anderson, J. L.; Meece, J. K.; Aggery, S. E.; Rekaya, R.; Alabady, M.; Belanger, M.; Winker, K.; Faircloth, B. C.

10.1101/049114 — genomics — Posted on 2019-03-05

2892 The phytopathogenic nature of Dickeya aquatica 174/2 and the dynamic early evolution of Dickeya pathogenicity

Duprey, A.; Taib, N.; Leonard, S.; Garin, T.; Flandrois, J.-P.; Nasser, W.; Brochier-Armanet, C.; Reverchon, S.

10.1101/568105 — genomics — Posted on 2019-03-05

2893 Tissue-specific Hi-C analyses of rice, foxtail millet and maize suggest non-canonical function of plant chromatin domains

Dong, P.; Tu, X.; Li, H.; Zhang, J.; Grierson, D.; Li, P.; zhong, s.

10.1101/567883 — genomics — Posted on 2019-03-05

2894 Risk of differential cancer types over age in families with Li-Fraumeni syndrome: a validation study using multi-center cohorts

Shin, S. J.; Dodd, E.; Peng, G.; Bojadzieva, J.; Chen, J.; Amos, C.; Mai, P. L.; Savage, S. A.; Ballinger, M. L.; Thomas, D. M.; yuan, Y.; Strong, L. C.; Wang, W.

10.1101/567727 — genetics — Posted on 2019-03-05

2895 Analysis of factor V in zebrafish demonstrates minimal levels needed for hemostasis and risk stratifies human variants

Weyand, A. C.; Grzegorski, S. J.; Rost, M. S.; Lavik, K. I.; Ferguson, A. C.; Menegatti, M.; Richter, C. E.; Asselta, R.; Duga, S.; Peyvandi, F.; Shavit, J. A.

10.1101/567453 — genetics — Posted on 2019-03-05

2896 Resistance diagnostics as a public health tool to combat antibiotic resistance: A model-based evaluation

McAdams, D.; Wollein Waldetoft, K.; Tedijanto, C.; Lipsitch, M.; Brown, S. P.

10.1101/452656 — epidemiology — Posted on 2019-03-05

2897 Subtle, seasonal and potentially important: Are phytotoxic foliage leachates overlooked in plant invasion studies?

Jones, G.; Tomlinson, M.; Owen, R.; Scullion, J.; Winters, A.; Jenkins, T.; Ratcliffe, J.; Gwynn-Jones, D.

10.1101/566976 — ecology — Posted on 2019-03-05

2898 Shifted distribution baselines: neglecting long-term biodiversity records risks overlooking potentially suitable habitat for conservation management

Monsarrat, S.; Novellie, P.; Rushworth, I.; Kerley, G. I. H.

10.1101/565929 — ecology — Posted on 2019-03-05

2899 Field trial of a probiotic bacteria and a chemical, chitosan, to protect bats from white-nose syndrome

Hoyt, J. R.; Langwig, K. E.; White, J. P.; Kaarakka, H. M.; Redell, J. A.; Parise, K. L.; Frick, W. F.; Foster, J. T.; Kilpatrick, A. M.

10.1101/567826 — ecology — Posted on 2019-03-05

2900 The UCSC Xena platform for public and private cancer genomics data visualization and interpretation

Goldman, M.; Craft, B.; Hastie, M.; Repecka, K.; Kamath, A.; McDade, F.; Rogers, D.; Brooks, A. N.; Zhu, J.; Haussler, D.

10.1101/326470 — cancer biology — Posted on 2019-03-05

2901 Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma

De Crignis, E.; Carofiglio, F.; Moulos, P.; Verstegen, M. M. A.; Romal, S.; Khalid, M. M.; Pourfarzad, F.; Koutsothanassis, C.; Gehart, H.; Kan, T. W.; Palstra, R.-J.; Boucher, C.; IJzermans, J.; Huch, M.; Boj, S.; Vries, R.; Clevers, H.; van der Laan, L.; Hatzis, P.; Mahmoudi, T.

10.1101/568147 — cancer biology — Posted on 2019-03-05

2902 A pressure sensing protein kinase

Akella, R.; Sekulski, K.; Pleinis, J. M.; Liwocha, J.; Jiou, J.; He, H.; Humphreys, J. M.; Schellinger, J. N.; Joachimiak, L.; Rodan, A. R.; Goldsmith, E. J.

10.1101/435008 — biophysics — Posted on 2019-03-05

2903 GPseudoClust: deconvolution of shared pseudo-trajectories at single-cell resolution

Strauss, M.; Kirk, P. D.; Reid, J. E.; Wernisch, L.

10.1101/567115 — bioinformatics — Posted on 2019-03-05

2904 Unsupervised Toxoplasma gondii Recognition by Fuzzy Cycle Generative Adversarial Network

Li, S.; Li, A.; Lara, D. A. M.; Gomez Marin, J. E.; Zhang, Y.

10.1101/567891 — bioinformatics — Posted on 2019-03-05

2905 Integrating deep and radiomics features in cancer bioimaging

Bizzego, A.; Bussola, N.; Salvalai, D.; Chierici, M.; Maggio, V.; Jurman, G.; Furlanello, C.

10.1101/568170 — bioinformatics — Posted on 2019-03-05

2906 Mechanics of wood boring by beetle mandibles

Kundanati, L.; Chahare, N. R.; Jaddivada, S.; Karkisaval, A. G.; Pugno, N. M.; Gundiah, N.

10.1101/568089 — bioengineering — Posted on 2019-03-05

2907 Identification of novel glycosylation events on human serum-derived Factor IX

Pegg, C. L.; Zacchi, L. F.; Roche Recinos, D.; Howard, C. B.; Schulz, B. L.

10.1101/567941 — biochemistry — Posted on 2019-03-05

2908 Sex and age don’t matter but breed type does - Factors influencing eye wrinkle expression in horses

Schanz, L.; Krueger, K.; Hintze, S.

10.1101/567149 — animal behavior and cognition — Posted on 2019-03-05

2909 Towards an individualised neural assessment of receptive language in children

Petit, S.; Badcock, N. A.; Grootswagers, T.; Rich, A. N.; Brock, J.; Nickels, L.; Moerel, D.; Dermody, N.; Yau, S.; Schmidt, E.; Woolgar, A.

10.1101/566752 — animal behavior and cognition — Posted on 2019-03-05

2910 A decade of empirical research on research integrity: what have we (not) looked at?

Aubert Bonn, N.; Pinxten, W.

10.1101/567263 — scientific communication and education — Posted on 2019-03-05

2911 Application of Global Metabolomics to the Identification of Complex Counterfeit Medicinal Products

Jenkins, C.; Orsburn, B.

10.1101/567339 — pharmacology and toxicology — Posted on 2019-03-05

2912 Retinal and Cortical Determinants of Cortical Magnification in Human Albinism

Woertz, E. N.; Wilk, M. A.; Duwell, E.; Mathis, J.; Carroll, J.; DeYoe, E. A.

10.1101/562249 — neuroscience — Posted on 2019-03-05

2913 The neurofunctional basis of affective startle modulation in humans - evidence from combined facial EMG-fMRI

Kuhn, M.; Wendt, J.; Sjouwerman, R.; Büchel, C.; Hamm, A.; Lonsdorf, T. B.

10.1101/567032 — neuroscience — Posted on 2019-03-05

2914 Dynamics of dual specificity phosphatases and their interplay with protein kinases in immune signaling

Subbannayya, Y.; Pinto, S.; Bosl, K.; Prasad, T. S. K.; Kandasamy, R. K.

10.1101/568576 — immunology — Posted on 2019-03-05

2915 Genomic architecture of phenotypic plasticity of complex traits in tetraploid wheat in response to water stress

Fatiukha, A.; Deblieck, M.; Klymiuk, V.; Merchuk-Ovnat, L.; Peleg, Z.; Ordon, F.; Fahima, T.; Saranga, A. B.; Saranga, Y.; Krugman, T.

10.1101/565820 — genetics — Posted on 2019-03-05

2916 Improved HLA-based prediction of coeliac disease identifies two novel HLA risk modifiers, DQ6.2 and DQ7.3

Erlichster, M.; Bedo, J.; Skafidas, E.; Kwan, P.; Kowalczyk, A.; Goudey, B.

10.1101/561308 — genetics — Posted on 2019-03-05

2917 An R Implementation of Tumor-Stroma-Immune Transcriptome Deconvolution Pipeline using DeMixT

Cao, S.; Wang, Z.; Gao, F.; Chen, J.; Zhang, F.; Frigo, D. E.; Efstathiou, E.; Kopetz, S.; Wang, W.

10.1101/566075 — bioinformatics — Posted on 2019-03-05

2918 The Tangent copy-number inference pipeline for cancer genome analyses

Tabak, B.; Saksena, G.; Oh, C.; Gao, G. F.; Hill Meyers, B.; Reich, M.; Schumacher, S. E.; Westlake, L. C.; Berger, A. C.; Carter, S. L.; Cherniack, A. D.; Meyerson, M.; Beroukhim, R.; Getz, G.

10.1101/566505 — bioinformatics — Posted on 2019-03-05

2919 EPIC: MHC-I epitope prediction integrating mass spectrometry derived motifs and tissue-specific expression profiles

Hu, W.; Qiu, S.; Li, Y.; Lin, X.; Zhang, L.; Xiang, H.; Han, X.; Chen, L.; Li, S.; Li, W.; Ren, Z.; Hou, G.; Lin, Z.; Lu, J.; Liu, G.; Li, B.; Lee, L.

10.1101/567081 — bioinformatics — Posted on 2019-03-05

2920 Comprehensive analysis of the internal structure and firmness in American cranberry (Vaccinium macrocarpon Ait.) fruit

Diaz-Garcia, L.; Rodriguez-Bonilla, L.; Phillips, M.; Lopez-Hernandez, A.; Grygleski, E.; Atucha, A.; Zalapa, J.

10.1101/567958 — plant biology — Posted on 2019-03-05

2921 Plant photoreceptors and their signaling components compete for binding to the ubiquitin ligase COP1 using their VP-peptide motifs

Lau, K.; Podolec, R.; Chappuis, R.; Ulm, R.; Hothorn, M.

10.1101/568618 — plant biology — Posted on 2019-03-05

2922 DNA sequence differences and temperature are determinants of meiotic recombination outcome

Brown, S. D.; Asogwa, M. N.; Jezequel, M.; Charlotte, A.; Mpaulo, S. J.; Whitby, M. C.; Lorenz, A.

10.1101/568543 — genetics — Posted on 2019-03-05

2923 Evaluating genomic data for management of local adaptation in a changing climate: A lodgepole pine case study

Mahony, C. R.; MacLachlan, I. R.; Lind, B. M.; Yoder, J. B.; Wang, T.; Aitken, S. N.

10.1101/568725 — evolutionary biology — Posted on 2019-03-05

2924 Effect of time-series length and resolution on abundance- and trait-based early warning signals of population declines

Arkilanian, A.; Clements, C. F.; Ozgul, A.; Baruah, G.

10.1101/568600 — ecology — Posted on 2019-03-05

2925 Molecular Correlations between Breast Cancer and Diabetes Mellitus Type 2 Examined by In Silico analyses and Drug Inhibitory Effects

Afzali, F.; Nayeri, Z.; Minuchehr, Z.; Gardaneh, M.

10.1101/568634 — cancer biology — Posted on 2019-03-05

2926 Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer

Kim, Y.-A.; Wojtowicz, D.; Sarto Basso, R.; Sason, I.; Robinson, W.; Hochbaum, D. S.; Leiserson, M. D. M.; Sharan, R.; Vandin, F.; Przytycka, T. M.

10.1101/568568 — bioinformatics — Posted on 2019-03-05

2927 An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation

Kalesh, K.; Lukauskas, S.; Borg, A. J.; Snijders, A. P.; Leung, A. K. L.; Haskard, D. O.; DiMaggio, P. A.

10.1101/568527 — biochemistry — Posted on 2019-03-05

2928 Bioisosterism reveals new structure-odor relationships

Tahirova, N.; Poivet, E.; Xu, L.; Peterlin, Z.; Zou, D.-J.; Firestein, S.

10.1101/567701 — neuroscience — Posted on 2019-03-05

2929 Content-based dissociation of hippocampal involvement in prediction

Kok, P.; Rait, L. I.; Turk-Browne, N. B.

10.1101/568303 — neuroscience — Posted on 2019-03-05

2930 Neural precursors of decisions that matter--an ERP study of deliberate and arbitrary choice

Maoz, U.; Yaffe, G.; Koch, C.; Mudrik, L.

10.1101/097626 — neuroscience — Posted on 2019-03-05

2931 Detection of Base Analogs Incorporated During DNA Replication by Nanopore Sequencing

Georgieva, D.; Liu, Q.; Wang, K.; Egli, D.

10.1101/549220 — genomics — Posted on 2019-03-05

2932 Increasing the value of raw bulk milk quality based on mammary glands as production units vs. the udder in dairy cows with mastitis

Leitner, G.; Lavon, Y.; Merin, U.; Jacoby, S.; Blum, S. E.; Krifucks, O.; Silanikove, N.

10.1101/567271 — systems biology — Posted on 2019-03-05

2933 StomataCounter: a neural network for automatic stomata identification and counting.

Fetter, K. C.; Eberhardt, S.; Barclay, R. S.; Wing, S.; Keller, S. R.

10.1101/327494 — plant biology — Posted on 2019-03-05

2934 A model of the entrance pupil of the human eye

Aguirre, G. K.

10.1101/325548 — neuroscience — Posted on 2019-03-05

2935 Evaluating fMRI-Based Estimation of Eye Gaze during Naturalistic Viewing

Son, J.; Ai, L.; Lim, R.; Xu, T.; Colcombe, S.; Franco, A.; Cloud, J.; LaConte, S.; Lisinski, J.; Klein, A.; Craddock, C.; Milham, M.

10.1101/347765 — neuroscience — Posted on 2019-03-05

2936 A Tale of Two Positivities and the N400: Distinct neural signatures are evoked by confirmed and violated predictions at different levels of representation

Kuperberg, G.; Brothers, T.; Wlotko, E.

10.1101/404780 — neuroscience — Posted on 2019-03-05

2937 Adapterama III: Quadruple-indexed, double/triple-enzyme RADseq libraries (2RAD/3RAD)

10.1101/205799 — genomics — Posted on 2019-03-05

2938 Content of and interactions between repetitive elements in programmatically eliminated chromosomes of the sea lamprey (Petromyzon marinus)

Timoshevskiy, V. A.; Timoshevskaya, N. Y.; Smith, J. J.

10.1101/567370 — genetics — Posted on 2019-03-05

2939 Bayesian arrival model for Atlantic salmon smolt counts powered by environmental covariates and expert knowledge

Pulkkinen, H.; Orell, P.; Erkinaro, J.; Mantyniemi, S.

10.1101/399618 — ecology — Posted on 2019-03-05

2940 Impacts of climate change on high priority fruit fly species in Australia

Sultana, S.; Baumgartner, J. B.; Dominiak, B. C.; Royer, J. E.; Beaumont, L. J.

10.1101/567321 — ecology — Posted on 2019-03-05

2941 GVC: A superfast and universal genomic variant caller

Zhang, Z.; Yin, L.; hao, l.; Cao, L.; Liu, C.; Chen, M.; Li, C.; Xu, Z.; Ling, S.

10.1101/182089 — bioinformatics — Posted on 2019-03-05

2942 Genome-wide association analysis of 350,000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema.

Johansson, A.; Rask-Andersen, M.; Karlsson, T.; Ek, W. E.

10.1101/195933 — genetics — Posted on 2019-03-05

2943 Ancestry-specific association mapping in admixed populations

Skotte, L.; Jorsboe, E.; Korneliussen, T. S.; Moltke, I.; Albrechtsen, A.

10.1101/014001 — genetics — Posted on 2019-03-05

2944 Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation

Price, A. J.; Hwang, T.; Tao, R.; Burke, E. E.; Rajpurohit, A.; Shin, J.; Hyde, T. M.; Kleinman, J. E.; Jaffe, A. E.; Weinberger, D.

10.1101/567966 — neuroscience — Posted on 2019-03-05

2945 Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections

Pauli, M.; Paul, M. M.; Proppert, S.; Sharifi, M.; Repp, F.; Kollmannsberger, P.; Sauer, M.; Heckmann, M.; Siren, A.-L.

10.1101/568279 — neuroscience — Posted on 2019-03-05

2946 Heterozygous variants in KMT2E cause a spectrum of neurodevelopmental disorders and epilepsy

O'Donnell-Luria, A. H.; Pais, L. S.; Faundes, V.; Wood, J. C.; Sveden, A.; Luria, V.; Abou Jamra, R.; Accogli, A.; Amburgey, K.; Anderlid, B.-M.; Azzarello-Burri, S.; Basinger, A. A.; Bianchini, C.; Bird, L. M.; Buchert, R.; Carre, W.; Ceulemans, S.; Charles, P.; Cox, H.; Culliton, L.; Curro, A.; Deciphering Developmental Disorders (DDD) Study, ; Demurger, F.; Dowling, J. J.; Duban-Bedu, B.; Dubourg, C.; Escobar, L. F.; Ferrarini, A.; Haack, T. B.; Hashim, M.; Heide, S.; Helbig, K. L.; Helbig, I.; Heredia, R.; Heron, D.; Isidor, B.; Jonasson, A. R.; Joset, P.; Keren, B.; Kok, F.; Kroes, H. Y

10.1101/566091 — genetics — Posted on 2019-03-05

2947 About samples, giving examples: Optimized Single Molecule Localization Microscopy

Jimenez, A.; Friedl, K.; Leterrier, C.

10.1101/568295 — cell biology — Posted on 2019-03-05

2948 Chronic unpredictable stress promotes cell-specific plasticity in prefrontal cortex D1 and D2 pyramidal neurons

Anderson, E.; Gomez, D.; Caccamise, A.; McPhail, D.; Hearing, M.

10.1101/565499 — neuroscience — Posted on 2019-03-05

2949 Decoding mouse behavior to explain single-trial decisions and their relationship with neural activity.

Weissenberger, Y.; King, A. C.; Dahmen, J. J.

10.1101/567479 — neuroscience — Posted on 2019-03-05

2950 Arabidopsis phytochelatin synthase 1, but not phytochelatin synthesis, functions in extracellular defense against multiple fungal pathogens

Hematy, K.; Lim, M.; Cherk, C.; Bednarek, P.; Pislewska-Bednarek, M.; Sanchez-Rodriguez, C.; Stein, M.; Fuchs, R.; Klapprodt, C.; Lipka, V.; Molina, A.; Grill, E.; Schulze-Lefert, P.; Somerville, S.

10.1101/568113 — plant biology — Posted on 2019-03-05

2951 Plant-soil feedback contributes to predicting plant invasiveness of 68 alien plant species differing in invasive status

Aldorfova, A.; Knobova, P.; Munzbergova, Z.

10.1101/568048 — plant biology — Posted on 2019-03-05

2952 Time course of the physiological stress response to an acute stressor and its associations with the primacy and recency effect of the serial position curve

Becker, L.; Rohleder, N.

10.1101/568352 — physiology — Posted on 2019-03-05

2953 Kinematics associated with treadmill walking in Rett Syndrome

Layne, C. S.; Young, D. R.; Lee, B.-C.; Glaze, D. G.; Schwabe, A.; Suter, B.

10.1101/568360 — neuroscience — Posted on 2019-03-05

2954 Global assessment of Mycobacterium avium subspecies hominissuis genetic requirement for growth and virulence.

Dragset, M. S.; Ioerger, T. R.; Loevenich, M.; Haug, M.; Sivakumar, N.; Marstad, A.; Cardona, P. J.; Klinkenberg, G.; Rubin, E. J.; Steigedal, M.; Flo, T. H.

10.1101/568477 — microbiology — Posted on 2019-03-05

2955 The Klebsiella pneumoniae citrate synthase gene, gltA, influences site specific fitness during infection

Vornhagen, J.; Sun, Y.; Breen, P.; Forsyth, V.; Zhao, L.; Mobley, H. L. T.; Bachman, M. A.

10.1101/568493 — microbiology — Posted on 2019-03-05

2956 HIV-1 co-receptor usage and variable loop contact impacts V3 loop bnAb susceptibility

Registre, L.; Moreau, Y.; Toksoz Ataca, S.; Pulukuri, S.; Henrich, T. J.; Lin, N.; Sagar, M.

10.1101/568469 — microbiology — Posted on 2019-03-05

2957 Perinatal features of Prader-Willi syndrome: a Chinese cohort

Yang, L.; Zhou, Q.; Ma, B.; Mao, S.; Dai, Y.; Zhu, M.; ZOU, C.-C.

10.1101/568451 — genetics — Posted on 2019-03-05

2958 Impact of an intra-abdominal cooling device during open kidney transplantation in pigs

Longchamp, A.; Meier, R. P. H.; Colucci, N.; Balaphas, A.; Orci, L.; Nastasi, A.; Longchamp, G.; Moll, S.; Klauser, A.; Pascual, M.; Lazeyras, F.; Corpataux, J.-M.; Bühler, L.

10.1101/568402 — physiology — Posted on 2019-03-05

2959 Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression

Despang, A.; Schöpflin, R.; Franke, M.; Ali, S.; Jerkovic, I.; Paliou, C.; Chan, W.-L.; Timmermann, B.; Wittler, L.; Vingron, M.; Mundlos, S.; Ibrahim, D. M.

10.1101/566562 — genetics — Posted on 2019-03-05

2960 Towards a further understanding of measles vaccine hesitancy in Khartoum state, Sudan: A qualitative study

Sabahelzain, M. M.; Moukhyer, M.; Dube, E.; Hardan, A.; Bosma, H.; van den Borne, B.

10.1101/568345 — epidemiology — Posted on 2019-03-05

2961 Niche partitioning and coexistence of two spiders of the genus Peucetia (Araneae, Oxyopidae) inhabiting Trichogoniopsis adenantha plants (Asterales, Asteraceae): a population approach

Villanueva, G. A.; Safuan-Naide, S.; Pires, M.; Vasconcellos-Neto, J.

10.1101/568410 — ecology — Posted on 2019-03-05

2962 Midgut Transcriptome Analysis of Clostera anachoreta Treated with Cry1Ac Toxin

Liu, J.; Gao, B.; Wang, L.; Zhou, G.; Liu, J.

10.1101/568337 — zoology — Posted on 2019-03-05

2963 The Arabian camel, Camelus dromedarius interferon epsilon: functional expression, in vitro refolding, purification and cytotoxicity on breast cancer cell lines MDA-MB-231 and MCF-7

Saeed, H.; Abdelfattah, M.; El-Shennawy, L.; Shalaby, M.; Embaby, A.; Ataya, F.; Eed, H.; Hussein, A.

10.1101/568329 — molecular biology — Posted on 2019-03-05

2964 Human antiviral protein MxA forms novel metastable membrane-less cytoplasmic condensates exhibiting rapid reversible \"crowding\"-driven phase transitions

Davis, D.; Yuan, H.; Liang, F.-X.; Yang, Y.-M.; Westley, J.; Petzold, C.; Dancel-Manning, K.; Deng, Y.; Sall, J.; Sehgal, P. B.

10.1101/568006 — cell biology — Posted on 2019-03-05

2965 NMDA receptors enhance the fidelity of synaptic integration

Li, C.; Baker, A. L.; Gulledge, A. T.

10.1101/566117 — neuroscience — Posted on 2019-03-05

2966 Targeting the mTORC2 signaling complex in B cell malignancies.

Liao, W.; Jordaan, G.; Benavides-Serrato, A.; Holmes, B.; Gera, J.; Sharma, S.

10.1101/564500 — cancer biology — Posted on 2019-03-05

2967 Carbon stocks of coastal seagrass in Southeast Asia may be far lower than anticipated when accounting for black carbon

Gallagher, J. B.; Chuan, C. H.; Yap, T. K.; Farahain, W.

10.1101/493262 — plant biology — Posted on 2019-03-05

2968 A genetic link between leaf carbon isotope composition and whole-plant water use efficiency in the C4 grass Setaria

Ellsworth, P.; Feldman, M.; Baxter, I.; Cousins, A.

10.1101/285676 — plant biology — Posted on 2019-03-05

2969 Enduring and sex-specific changes in hippocampal gene expression after a subchronic immune challenge

Tchessalova, D.; Tronson, N. C.

10.1101/566570 — neuroscience — Posted on 2019-03-05

2970 Network resonance during slow-wave sleep facilitates memory consolidation through phase-coding

Skilling, Q.; Clawson, B. C.; Eniwaye, B.; Shaver, J.; Ognjanovski, N.; Atan, S. J.; Zochowski, M.

10.1101/565242 — neuroscience — Posted on 2019-03-05

2971 Shared neural underpinnings of multisensory integration and trial-by-trial perceptual recalibration

Park, H.; Kayser, C.

10.1101/566927 — neuroscience — Posted on 2019-03-05

2972 Supporting global biodiversity assessment through high-resolution macroecological modelling: Methodological underpinnings of the BILBI framework

Hoskins, A. J.; Harwood, T. D.; Ware, C.; Williams, K. J.; Perry, J. J.; Ota, N.; Croft, J. R.; Yeates, D. K.; Jetz, W.; Golebiewski, M.; Purvis, A.; Ferrier, S.

10.1101/309377 — ecology — Posted on 2019-03-05

2973 Pluripotency factors regulate the onset of Hox cluster activation in the early embryo

Lopez-Jimenez, E.; Sainz de Aja, J.; Badia-Careaga, C.; Barral, A.; Rollan, I.; Rouco, R.; Santos, E.; Tiana, M.; Victorino, J.; Sanchez-Iranzo, H.; Acemel, R. D.; Torroja, C.; Adan, J.; Andres-Leon, E.; Gomez-Skarmeta, J. L.; Giovinazzo, G.; Sanchez-Cabo, F.; Manzanares, M.

10.1101/564658 — developmental biology — Posted on 2019-03-05

2974 Syndecan-1 facilitates breast cancer metastasis to the brain

Sayyad, M. R.; Puchalapalli, M.; Vergara, N. G.; Mosticone Wangensteen, S.; Moore, M.; Mu, L.; Edwards, C.; Anderson, A.; Kall, S.; Sullivan, M.; Dozmorov, M.; Singh, J.; Idowu, M. O.; Koblinski, J. E.

10.1101/565648 — cancer biology — Posted on 2019-03-05

2975 Non-responder phenotype reveals microbiome-wide antibiotic resistance in the murine gut

Diener, C.; Hoge, A. C.; Kearney, S. M.; Edman, S. E.; Gibbons, S. M.

10.1101/566190 — systems biology — Posted on 2019-03-04

2976 A Monte Carlo method for in silico modeling and visualization of Waddington’s epigenetic landscape with intermediate details

Zhang, X.; Chong, K. H.; Zheng, J.

10.1101/310771 — systems biology — Posted on 2019-03-04

2977 Experimental Assessment of PCR Specificity and Copy Number for Reliable Data Retrieval in DNA Storage

Organick, L. W.; Chen, Y.-J.; Dumas Ang, S.; Lopez, R.; Strauss, K.; Ceze, L.

10.1101/565150 — synthetic biology — Posted on 2019-03-04

2978 Redundant SCARECROW genes pattern distinct cell layers in roots and leaves of maize

Hughes, T. E.; Sedelnikova, O. V.; Wu, H.; Becraft, P. W.; Langdale, J. A.

10.1101/567156 — plant biology — Posted on 2019-03-04

2979 Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal muscle of H6PDH KO mice

Doig, C. L.; Zelinska, A.; Oakey, L.; Fletcher, R.; El Hassan, Y.; Garten, A.; Cartwright, D.; Heising, S.; Tennant, D.; Watson, D.; Adamski, J.; Lavery, G.

10.1101/567297 — physiology — Posted on 2019-03-04

2980 FUS ALS-causative mutations impact FUS autoregulation and the processing of RNA-binding proteins through intron retention

Humphrey, J.; Birsa, N.; Milioto, C.; Robaldo, D.; Bentham, M.; Jarvis, S.; Bodo, C.; Garone, M. G.; Devoy, A.; Rosa, A.; Bozzoni, I.; Fisher, E.; Ruepp, M.-D.; Schiavo, G.; Isaacs, A.; Plagnol, V.; Fratta, P.

10.1101/567735 — neuroscience — Posted on 2019-03-04

2981 Hidden neural states underlie canary song syntax

Cohen, Y.; Shen, J.; Semu, D.; Leman, D. P.; Liberti, W. A.; Perkins, N. L.; Liberti, D. C.; Kotton, D.; Gardner, T. J.

10.1101/561761 — neuroscience — Posted on 2019-03-04

2982 Somatostatin-Expressing Interneurons Co-Release GABA and Glutamate onto Different Postsynaptic Targets in the Striatum.

Cattaneo, S.; Zaghi, M.; Ripamonti, M.; Bedogni, F.; Sessa, A.; Taverna, S.

10.1101/566984 — neuroscience — Posted on 2019-03-04

2983 Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on glutamate-induced Ca2+ response

Liu, G.; Thangavel, R.; Rysted, J.; Kim, Y.; Francis, M. B.; Adams, E.; Lin, Z.; Taugher, R. J.; Wemmie, J. A.; Usachev, Y. M.; Lee, G.

10.1101/567776 — neuroscience — Posted on 2019-03-04

2984 Differential effects of diet and weight on taste responses in diet-induced obese mice

Ahart, Z. C.; Martin, L. E.; Kemp, B. R.; Dutta Banik, D.; Roberts, S. G. E.; Torregrossa, A. M.; Medler, K.

10.1101/564211 — neuroscience — Posted on 2019-03-04

2985 Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing

Flynn, L. L.; Li, R.; Aung-Htut, M. T.; Pitout, I. L.; Cooper, J. A. L.; Hubbard, A.; Griffiths, L.; Bond, C.; Wilton, S. D.; Fox, A. H.; Fletcher, S.

10.1101/446773 — molecular biology — Posted on 2019-03-04

2986 Identification of RBPMS as a smooth muscle master splicing regulator via proximity of its gene with super-enhancers

Nakagaki-Silva, E. E.; Gooding, C.; Llorian, M.; Jacob, A. G.; Richards, F.; Buckroyd, A.; Sinha, S.; Smith, C. W.

10.1101/563304 — molecular biology — Posted on 2019-03-04

2987 A hidden battle in the dirt: soil amoebae interactions with Paracoccidioides spp

Albuquerque, P.; Nicola, A. M.; Magnabosco, D. A. G.; Derengowski, L. d. S.; Crisostomo, L. S.; Xavier, L. C. G.; Frazao, S. O.; Guilhelmelli, F.; Oliveira, M. A.; Hurtado, F. A.; Teixeira, M. M.; Guimaraes, A. J.; Paes, H. C.; Bagagli, E.; Felipe, M. S. S.; Casadevall, A.; Silva-Pereira, I.

10.1101/564435 — microbiology — Posted on 2019-03-04

2988 Environmental plasticity and colonisation history in the Atlantic salmon microbiome: a translocation experiment

Uren Webster, T.; Rodriguez Barreto, D.; Castaldo, G.; Gough, P.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/564104 — microbiology — Posted on 2019-03-04

2989 Modulation of Flagellar Rotation in Surface-Attached Bacteria: A Circuit for Rapid Surface-Sensing

Schniederberend, M.; Johnston, J. F.; Shine, E. E.; Shen, C.; Jain, R.; Emonet, T.; Kazmierczak, B.

10.1101/567438 — microbiology — Posted on 2019-03-04

2990 Pan-viral protection against arboviruses by targeting inoculation site-based skin macrophages

Bryden, S. R.; Pingen, M.; Lefteri, D. R.; Major, J.; Delang, L.; Jacobs, S.; Abdelnabi, R.; Neyts, J.; Miltenburg, J.; Khalid, H.; Tuplin, A.; Merits, A.; Pondeville, E.; Edgar, J.; Graham, G. J.; Shams, K.; McKimmie, C.

10.1101/566885 — immunology — Posted on 2019-03-04

2991 Gene expression profiles and pathway enrichment analysis to identification of differentially expressed gene and signaling pathways in epithelial ovarian cancer based on high-throughput RNA-seq data

siavoshi, A.; Taghizadeh, M.; Dookhe, E.; Piran, M.

10.1101/566331 — genomics — Posted on 2019-03-04

2992 Hierarchical clustering of gene-level association statistics reveals shared and differential genetic architecture among traits in the UK Biobank

McGuirl, M. R.; Smith, S. P.; Sandstede, B.; Ramachandran, S.

10.1101/565903 — genomics — Posted on 2019-03-04

2993 Genes essential for embryonic stem cells are associated with neurodevelopmental disorders

Shohat, S.; Shifman, S.

10.1101/567073 — genomics — Posted on 2019-03-04

2994 A robust and efficient method for Mendelian randomization with hundreds of genetic variants: unravelling mechanisms linking HDL-cholesterol and coronary heart disease

Burgess, S.; Foley, C. N.; Allara, E.; Staley, J. R.; Howson, J. M.

10.1101/566851 — genetics — Posted on 2019-03-04

2995 The nonlinear structure of linkage disequilibrium

Smith, R. D.

10.1101/566208 — genetics — Posted on 2019-03-04

2996 Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

Soskic, B.; Cano Gamez, E.; Smith, D. J.; Rowan, W. C.; Nakic, N.; Esparza-Gordillo, J.; Bossini-Castillo, L.; Tough, D. F.; Larminie, C. G. C.; Bronson, P. G.; Wille, D.; Trynka, G.

10.1101/566810 — genetics — Posted on 2019-03-04

2997 Mutation profiling of both cfDNAs and CTCs in gynecological cancer patients

Lee, S.-Y.; Chae, D.-k.; An, J.; Jung, S.; Bhak, J.; Kim, B. C.; Cho, D.-H.

10.1101/566786 — genetics — Posted on 2019-03-04

2998 Major QTLs for resistance to early and late leaf spot diseases are identified on chromosomes 3 and 5 in peanut (Arachis hypogaea)

Chu, Y.; Chee, P.; Culbreath, A. K.; Isleib, T. G.; Holbrook, C. C.; Ozias-Akins, P.

10.1101/567206 — genetics — Posted on 2019-03-04

2999 The role of insulators in transgene transvection in Drosophila

Piwko, P.; Vitsaki, I.; Livadaras, I.; Delidakis, C.

10.1101/565846 — genetics — Posted on 2019-03-04

3000 SimRVSequences: an R package to simulate genetic sequence data for pedigrees

Nieuwoudt, C.; Brooks-Wilson, A.; Graham, J.

10.1101/534552 — genetics — Posted on 2019-03-04

3001 Genomic Bayesian confirmatory factor analysis and Bayesian network to characterize a wide spectrum of rice phenotypes

Yu, H.; Campbell, M. T.; Zhang, Q.; Walia, H.; Morota, G.

10.1101/435792 — genetics — Posted on 2019-03-04

3002 From root to tips: sporulation evolution and specialization in Bacillus subtilis and the intestinal pathogen Clostridioides difficile

Ramos-Silva, P.; Serrano, M.; Henriques, A. O.

10.1101/473793 — evolutionary biology — Posted on 2019-03-04

3003 Testing for correlation between traits under directional evolution

Royer-Carenzi, M.; Didier, G.

10.1101/566349 — evolutionary biology — Posted on 2019-03-04

3004 Ant collective behavior is heritable and shaped by selection

Walsh, J. T.; Garnier, S.; Linksvayer, T. A.

10.1101/567503 — evolutionary biology — Posted on 2019-03-04

3005 Role of α-Catenin and its mechanosensing properties in the regulation of Hippo/YAP-dependent tissue growth

Sarpal, R.; Yan, V.; Kazakova, L.; Sheppard, L.; Tepass, U.

10.1101/567750 — cell biology — Posted on 2019-03-04

3006 A Cryo-EM Grid Preparation Device for Time-Resolved Structural Studies

Kontziampasis, D.; Klebl, D. P.; Iadanza, M. G.; Scarff, C. A.; Kopf, F.; Sobott, F.; Monteiro, D. C. F.; Trebbin, M.; Muench, S. P.; White, H. D.

10.1101/563254 — biophysics — Posted on 2019-03-04

3007 A high-resolution pipeline for 16S-sequencing identifies bacterial strains in human microbiome

Segota, I.; Long, T.

10.1101/565572 — bioinformatics — Posted on 2019-03-04

3008 Nebula: Ultra-efficient mapping-free structural variant genotyper

Khorsand, P.; Hormozdiari, F.

10.1101/566620 — bioinformatics — Posted on 2019-03-04

3009 Machine-learning a virus assembly fitness landscape

Dechant, P.-P.; He, Y.-H.

10.1101/567610 — bioinformatics — Posted on 2019-03-04

3010 Biological Filtering and Substrate Promiscuity Prediction for Annotating Untargeted Metabolomics

Hassanpour, N.; Alden, N.; Menon, R.; Jayaraman, A.; Lee, K.; Hassoun, S.

10.1101/558973 — bioengineering — Posted on 2019-03-04

3011 The reactivity of an unusual amidase may explain colibactin’s DNA cross-linking activity

Jiang, Y.; Stornetta, A.; Villalta, P. W.; Wilson, M. R.; Boudreau, P. D.; Zha, L.; Balbo, S.; Balskus, E. P.

10.1101/567248 — biochemistry — Posted on 2019-03-04

3012 Integrating behaviour and ecology into global biodiversity conservation strategies

Tobias, J. A.; Pigot, A. L.

10.1101/566406 — animal behavior and cognition — Posted on 2019-03-04

3013 Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats

Alonso, L.; Peeva, P.; Ramos-Prats, A.; Alenina, N.; Winter, Y.; Rivalan, M.

10.1101/566877 — animal behavior and cognition — Posted on 2019-03-04

3014 Single-cell RNA-sequencing of Herpes simplex virus 1-infected cells identifies NRF2 activation as an antiviral program

Wyler, E.; Franke, V.; Menegatti, J.; Kocks, C.; Boltengagen, A.; Praktiknjo, S.; Walch-Rueckheim, B.; Rajewsky, N.; Graesser, F.; Akalin, A.; Landthaler, M.

10.1101/566992 — systems biology — Posted on 2019-03-04

3015 Polychromatic solar energy conversion in pigment-protein chimeras that unite the two kingdoms of (bacterio)chlorophyll-based photosynthesis

Liu, J.; Friebe, V. M.; Frese, R. N.; Jones, M. R.

10.1101/565283 — synthetic biology — Posted on 2019-03-04

3016 Reconstructing the ecology of a Jurassic pseudoplanktonic megaraft colony

Hunter, A. W.; Mitchell, E. G.; Casenove, D.; Mayers, C.

10.1101/566844 — paleontology — Posted on 2019-03-04

3017 Rapid, precise, and reliable phenotyping of delay discounting using Bayesian adaptive design optimization

Ahn, W.-Y.; Gu, H.; Shen, Y.; Haines, N.; Teater, J. E.; Myung, J. I.; Pitt, M. A.

10.1101/567412 — neuroscience — Posted on 2019-03-04

3018 Deconvolving the contributions of cell-type heterogeneity on cortical gene expression

Patrick, E.; Taga, M.; Ergun, A.; Ng, B.; Casazza, W.; Cimpean, M.; Yung, C.; Schneider, J. A.; Bennet, D. A.; Gaiteri, C.; De Jager, P. L.; Bradshaw, E. M.; Mostafavi, S.

10.1101/566307 — neuroscience — Posted on 2019-03-04

3019 The cellular response towards lanthanum is substrate specific and reveals a novel route for glycerol metabolism in Pseudomonas putida KT2440

Wehrmann, M.; Toussaint, M.; Pfannstiel, J.; Billard, P.; Klebensberger, J.

10.1101/567529 — microbiology — Posted on 2019-03-04

3020 The Paf1 complex broadly impacts the transcriptome of Saccharomyces cerevisiae

Ellison, M. A.; Lederer, A. R.; Warner, M. H.; Mavrich, T.; Raupach, E. A.; Heisler, L. E.; Nislow, C.; Lee, M. T.; Arndt, K. M.

10.1101/567495 — genomics — Posted on 2019-03-04

3021 Systems biology of cold adaptation in the polyextremophilic red alga Galdieria sulphuraria

Rossoni, A. W.; Weber, A. P. M.

10.1101/565861 — evolutionary biology — Posted on 2019-03-04

3022 A Novel and Efficient Approach for Screening Cancer Cell Specific Monoclonal Antibodies

pei, X.-H.

10.1101/566398 — cancer biology — Posted on 2019-03-04

3023 Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

Pollock, K.; Liu, M.; Zaleska, M.; Pfuhl, M.; Collins, I.; Guettler, S.

10.1101/567446 — biophysics — Posted on 2019-03-04

3024 Uncovering hypergraphs of cell-cell interaction from single cell RNA-sequencing data

Tsuyuzaki, K.; Ishii, M.; Nikaido, I.

10.1101/566182 — bioinformatics — Posted on 2019-03-04

3025 Optogenetic control of cell morphogenesis on protein micropatterns

Zieske, K.; Mullins, R. D.

10.1101/563353 — bioengineering — Posted on 2019-03-04

3026 Characterizing the epigenetic landscape of cellular populations from bulk and single-cell ATAC-seq information.

Gabitto, M. I.; Rasmussen, A.; Wapinski, O.; Allaway, K.; Carriero, N.; Fishell, G. J.; Bonneau, R.

10.1101/567669 — bioinformatics — Posted on 2019-03-04

3027 Functional RNA Structures in the 3’UTR of Tick-Borne, Insect-Specific and No-Known-Vector Flaviviruses

Ochsenreiter, R.; Hofacker, I. L.; Wolfinger, M. T.

10.1101/565580 — bioinformatics — Posted on 2019-03-04

3028 12h-clock control of central dogma information flow by XBP1s

Pan, Y.; Ballance, H.; Schnytzer, Y.; Chen, X.; Levy, O.; Coarfa, C.; Zhu, B.

10.1101/559039 — systems biology — Posted on 2019-03-04

3029 Synthesis, SAR and Docking Studies of Substituted Aryl phenylthiazolyl phenylcarboxamide as potential PTP-1B Inhibitors

Varshney, K.; Gupta, A. K.; Rawat, A.; Srivastava, R.; Mishra, A.; Saxena, M.; Srivastava, A. K.; Jain, S.; Saxena, A. K.

10.1101/472670 — pharmacology and toxicology — Posted on 2019-03-04

3030 Linear cortico-cortical mapping as a fundamental motif of brain connectivity organization

O'Rawe, J. F.; Leung, H.-C.

10.1101/549345 — neuroscience — Posted on 2019-03-04

3031 Oxidative stress, telomere length, and frailty in an old age population

Martinez-Ezquerro, J. D.; Rodriguez-Castaneda, A.; Ortiz-Ramirez, M.; Sanchez-Garcia, S.; Rosas-Vargas, H.; Sanchez-Arenas, R.; Garcia-delaTorre, P.

10.1101/414680 — molecular biology — Posted on 2019-03-04

3032 Intra- and interpatient evolution of enterovirus D68 analyzed by whole-genome deep sequencing

Dyrdak, R.; Mastafa, M.; Hodcroft, E.; Neher, R.; Albert, J.

10.1101/420836 — microbiology — Posted on 2019-03-04

3033 Enteropathogen antibody dynamics and force of infection among children in low-resource settings

Arnold, B. F.; Martin, D. L.; Juma, J.; Mkocha, H.; Ochieng, J. B.; Cooley, G. M.; Omore, R.; Goodhew, E. B.; Morris, J. F.; Costantini, V.; Vinje, J.; Lammie, P. J.; Priest, J. W.

10.1101/522920 — epidemiology — Posted on 2019-03-04

3034 Carnivore endozoochory of a dry-fruited tree can benefit quarry passive restoration

Salgueiro, V.; Silva, C.; Eufrazio, S.; Salgueiro, P. A.; Vaz, P. G.

10.1101/561142 — ecology — Posted on 2019-03-04

3035 Optical flow analysis reveals that Kinesin-mediated advection impacts on the orientation of microtubules

Drechsler, M.; Lang, L. F.; Dirks, H.; Burger, M.; Schoenlieb, C.-B.; Palacios, I. M.

10.1101/556043 — cell biology — Posted on 2019-03-04

3036 Beware the Jaccard: the choice of metric is important and non-trivial in genomic colocalisation analysis.

Salvatore, S.; Rand, K. D.; Grytten, I.; Ferkingstad, E.; Domanska, D. E.; Holden, L.; Gheorghe, M.; Mathelier, A.; Glad, I.; Sandve, G. K.

10.1101/479253 — bioinformatics — Posted on 2019-03-04

3037 CRUMBLER: A tool for the Prediction of Ancestry in Cattle

Crum, T. E.; Schnabel, R. D.; Decker, J. E.; Regitano, L. C.; Taylor, J. F.

10.1101/396341 — genomics — Posted on 2019-03-04

3038 Global expansion and redistribution of Aedes-borne virus transmission risk with climate change

Ryan, S. J.; Carlson, C. J.; Mordecai, E. A.; Johnson, L. R.

10.1101/172221 — epidemiology — Posted on 2019-03-04

3039 Geography, not food availability, reflects compositional differences in the bacterial communities associated with larval sea urchins

Carrier, T.; Dupont, S.; Reitzel, A.

10.1101/394486 — ecology — Posted on 2019-03-04

3040 An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation

Tesi, A.; De Pretis, S.; Furlan, M.; Filipuzzi, M.; Morelli, M. J.; Andronache, A.; Doni, M.; Verrecchia, A.; Pelizzola, M.; Amati, B.; Sabo, A.

10.1101/561464 — cancer biology — Posted on 2019-03-04

3041 A comparative anatomy of protein crystals: lessons from the automatic processing of 56,000 samples

Svensson, O.; Gilski, M.; Nurizzo, D.; Bowler, M. W.

10.1101/558023 — biophysics — Posted on 2019-03-04

3042 Tailoring 3D cell culture templates with common hydrogels.

Pasturel, A.; Strale, P.-O.; Studer, V.

10.1101/370882 — bioengineering — Posted on 2019-03-04

3043 Human cortical organoids expose a differential function of GSK3 on direct and indirect neurogenesis

Lopez Tobon, A.; Villa, C. E.; Cheroni, C.; Trattaro, S.; Caporale, N.; Conforti, P.; Iennaco, R.; Lachgar, M.; Rigoli, M. T.; Marco de la Cruz, B.; Lo Riso, P.; Tenderini, E.; Troglio, F.; de Simone, M.; Liste, I.; Piccolo, S.; Macino, G.; Pagani, M.; Cattaneo, E.; Testa, G.

10.1101/484741 — developmental biology — Posted on 2019-03-04

3044 Modeling motor neuron resilience in ALS using stem cells

Allodi, I.; Nijssen, J.; Aguila Benitez, J. C.; Schweingruber, C.; Fuchs, A.; Bonvicini, G.; Cao, M.; Kiehn, O.; Hedlund, E.

10.1101/399659 — neuroscience — Posted on 2019-03-04

3045 Expanding Parkinson’s disease genetics: novel risk loci, genomic context, causal insights and heritable risk

Nalls, M. A.; Blauwendraat, C.; Vallerga, C. L.; Heilbron, K.; Bandres-Ciga, S.; Chang, D.; Tan, M.; Kia, D. A.; Noyce, A. J.; Xue, A.; Bras, J.; Young, E.; von Coelln, R.; Simon-Sanchez, J.; Schulte, C.; Sharma, M.; Krohn, L.; Pihlstrom, L.; Siitonen, A.; Iwaki, H.; Leonard, H.; Faghri, F.; Gibbs, J. R.; Hernandez, D. G.; Scholz, S. W.; Botia, J. A.; Martinez, M.; Corvol, J.-C.; Lesage, S.; Jankovic, J.; Shulman, L. M.; The 23andMe Research Team, ; System Genomics of Parkinson's Disease (SGPD) Cons, ; Sutherland, M.; Tienari, P.; Majamaa, K.; Toft, M.; Brice, A.; Yang, J.; Gan-Orr, Z.; Gas

10.1101/388165 — genetics — Posted on 2019-03-04

3046 High satellite repeat turnover in great apes studied with short- and long-read technologies

Cechova, M.; Harris, R. S.; Tomaszkiewicz, M.; Arbeithuber, B.; Chiaromonte, F.; Makova, K. D.

10.1101/470054 — evolutionary biology — Posted on 2019-03-04

3047 Neural circuits mediating visual stabilization during active motion in zebrafish

Sun, S.; Zuo, Z.; Ma, M. M.; Qian, C.; Chen, L.; Zhou, W.; Drasbek, K. R.; Zuxiang, L.

10.1101/566760 — neuroscience — Posted on 2019-03-04

3048 A distributed neural code in the dentate gyrus and CA1

Stefanini, F.; Kheirbek, M. A.; Kushnir, L.; Jimenez, J. C.; Jennings, J. H.; Stuber, G. D.; Hen, R.; Fusi, S.

10.1101/292953 — neuroscience — Posted on 2019-03-04

3049 Modulation of coordinated activity across cortical layers by plasticity of inhibitory synapses onto layer 5 pyramidal neurons

Lourenco, J.; De Stasi, A. M.; Deleuze, C.; Bigot, M.; Pazienti, A.; Aguirre, A.; Giugliano, M.; Ostojic, S.; Bacci, A.

10.1101/567065 — neuroscience — Posted on 2019-03-04

3050 Simulation of calcium signaling in fine astrocytic processes: effect of spatial properties on spontaneous activity

Denizot, A.; Arizono, M.; Nägerl, V.; Soula, H.; Berry, H.

10.1101/567388 — neuroscience — Posted on 2019-03-04

3051 Nanopore sequencing of full-length circRNAs in human and mouse brains reveals circRNA-specific exon usage and intron retention

Rahimi, K.; Veno, M. T.; Dupont, D. M.; Kjems, J.

10.1101/567164 — genetics — Posted on 2019-03-04

3052 Constraint-based analysis for causal discovery in population-based biobanks

Amar, D.; Ashley, E.; Rivas, M.

10.1101/566133 — genetics — Posted on 2019-03-04

3053 Genetic divergence and phenotypic plasticity contribute to variation in cuticular hydrocarbons in the seaweed fly C. frigida

Berdan, E. L.; Enge, S.; Nylund, G.; Wellenreuther, M.; Martens, G. A.; Pavia, H.

10.1101/303206 — evolutionary biology — Posted on 2019-03-04

3054 Ex vivo expansion of skeletal muscle stem cells with a novel small compound inhibitor of eIF2α dephosphorylation

Lean, G.; Halloran, M.; Mariscal, O.; Jamet, S.; Lumb, J.-P.; Crist, C.

10.1101/567461 — cell biology — Posted on 2019-03-04

3055 Two pathways of p27Kip1 degradation are required for murine lymphoma driven by Myc and EBV latent membrane protein 2A

Longnecker, R.; Ikeda, M.; Sora, R. P.

10.1101/564559 — microbiology — Posted on 2019-03-04

3056 Modelling microbiome recovery after antibiotics using a stability landscape framework

Shaw, L. P.; Bassam, H.; Barnes, C. P.; Walker, A. S.; Klein, N.; Balloux, F.

10.1101/222398 — microbiology — Posted on 2019-03-04

3057 UniProt Genomic Mapping for Deciphering Functional Effects of Missense Variants

McGarvey, P.; Nightingale, A.; Luo, J.; Huang, H.; Martin, M.-J.; Wu, C.; UniProt Consortium,

10.1101/192914 — genomics — Posted on 2019-03-04

3058 Chronic Intermittent Ethanol Exposure Differentially Alters Microglial Morphology in the Prelimbic Cortex and Nucleus Accumbens Core

Siemsen, B.; Landin, J.; McFaddin, J.; Hooker, K.; Chandler, L. J.; Scofield, M. D.

10.1101/566034 — neuroscience — Posted on 2019-03-04

3059 Functional arrays of human pluripotent stem cell-derived cardiac microtissues

Zandstra, P.; Thavandiran, N.; Hale, C.; Blit, P.; Sandberg, M. L.; McElvain, M. E.; Gagliardi, M.; Sun, B.; Witty, A.; Graham, G.; McIntosh, M.; Bakooshli, M. A.; Le, H.; Ostblom, J.; McEwen, S.; Chau, E.; Prowse, A.; Fernandes, I.; Gilbert, P. M.; Keller, G.; Tagari, P.; Xu, H.; Radisic, M.

10.1101/566059 — bioengineering — Posted on 2019-03-04

3060 Antigen structure affects cellular routing through DC-SIGN

Jarvis, C.; Zwick, D. B.; Grim, J. C.; Prost, L. R.; Alam, M. M.; Gardiner, J.; Park, S.; Zimdars, L. L.; Sherer, N. M.; Kiessling, L.

10.1101/566141 — immunology — Posted on 2019-03-04

3061 Complex polymorphic genetic architecture underlies trans-regulatory variation among strains of Saccharomyces cerevisiae

Metzger, B. P. H.; Wittkopp, P. J.

10.1101/566653 — evolutionary biology — Posted on 2019-03-04

3062 The Personal Genome Project-UK: an open access resource of human multi-omics data

Chervova, O.; Conde, L.; Guerra-Assuncao, J. A.; Moghul, I.; Webster, A. P.; Berner, A.; Larose Cadieux, E.; Tian, Y.; Voloshin, V.; Hamoudi, R. A.; Herrero, J.; Beck, S.

10.1101/566711 — bioinformatics — Posted on 2019-03-04

3063 Injectable nanoclay gels for angiogenesis

Page, D. J.; Clarkin, C. E.; Mani, R.; Khan, N. A.; Dawson, J. I.; Evans, N. D.

10.1101/566943 — bioengineering — Posted on 2019-03-04

3064 Quantifying Molecular Bias in DNA Data Storage

Chen, Y.-J.; Takahashi, C. N.; Organick, L.; Stewart, K.; Ang, S. D.; Weiss, P.; Peck, B.; Seelig, G.; Ceze, L.; Strauss, K.

10.1101/566554 — synthetic biology — Posted on 2019-03-04

3065 GAPIN: Grouped and Aligned Protein Interface Networks

Araujo, B. M.; Coelho, A. L.; Silveira, S. d. A.; Romanelli, J. P. R.; Minardi, R. C. d. M.; da Silveira, C. H.

10.1101/520833 — bioinformatics — Posted on 2019-03-04

3066 EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences

Zhang, H.; Ge, X.; Li, W. V.; Xie, L.; Kwon, S. B.; Li, J. J.

10.1101/566299 — bioinformatics — Posted on 2019-03-04

3067 Na/K-ATPase Activity and Ketone Body Metabolism in Long-term Diabetic Rats

Buxbaum, E.

10.1101/567180 — biochemistry — Posted on 2019-03-04

3068 Dynamics and Internal Control of Body Temperature in Response to Infectious Agents and other Causal Factors

Schaper, C.

10.1101/566679 — physiology — Posted on 2019-03-04

3069 Insights into an alternative pathway for glycerol metabolism in a glycerol kinase deficient Pseudomonas putida KT2440

Walsh, M.; Casey, W.; Kenny, S. T.; Narancic, T.; Blank, L. M.; Wierckx, N.; Ballerstedt, H.; O Connor, K. E.

10.1101/567230 — microbiology — Posted on 2019-03-04

3070 The impact of DNA polymerase and number of rounds of amplification in PCR on 16S rRNA gene sequence data

Sze, M. A.; Schloss, P. D.

10.1101/565598 — microbiology — Posted on 2019-03-04

3071 Chromatin arranges in filaments of blobs with nanoscale functional zonation

Miron, E.; Oldenkamp, R.; Pinto, D. M.; Brown, J. M.; Carvalho Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Buckle, V.; Schermelleh, L.

10.1101/566638 — genomics — Posted on 2019-03-04

3072 Single particle trajectory statistic to reconstruct chromatin organization and dynamics

Shukron, O.; Seeber, A.; Amitai, A.; Holcman, D.

10.1101/559369 — genomics — Posted on 2019-03-04

3073 EML4-ALK V3 drives cell migration through NEK9 and NEK7 kinases in non-small-cell lung cancer

O'Regan, L.; Barone, G.; Adib, R.; Woo, C. G.; Jeong, H. J.; Richardson, E.; Richards, M.; Muller, P.; Collis, S.; Fennell, D.; Choi, J.; Bayliss, R.; Fry, A. M.

10.1101/567305 — cancer biology — Posted on 2019-03-04

3074 TmDOTP : An NMR- based Thermometer for Magic Angle Spinning NMR Experiments

Zhang, D.; Itin, B.; McDermott, A.

10.1101/566729 — biophysics — Posted on 2019-03-04

3075 Molecular characterization of CHAD domains as inorganic polyphosphate binding modules

Lorenzo-Orts, L.; Hohmann, U.; Zhu, J.; Hothorn, M.

10.1101/567040 — biochemistry — Posted on 2019-03-04

3076 A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and GABAergic neurodevelopment in the medial prefrontal cortex

Reichelt, A. C.; Gibson, G. D.; Abbott, K. N.; Hare, D. J.

10.1101/566026 — neuroscience — Posted on 2019-03-04

3077 Multiple elements of addiction vulnerability are independently heritable in rats

Eid, M.; Pullmann, D.; Li, H.; Jhou, T.

10.1101/566018 — neuroscience — Posted on 2019-03-04

3078 Threshold Electric Skin Sensitivity Fluctuations in Pregnancy, Labor and Puerperium.

Rossmann, C. B. C.; Von Taaffe, C. T.

10.1101/565960 — neuroscience — Posted on 2019-03-04

3079 Norepinephrine controls the gain of the inhibitory circuit in the cerebellar input layer

Lanore, F.; Rothman, J.; Coyle, D.; Silver, R. A.

10.1101/567172 — neuroscience — Posted on 2019-03-04

3080 The processing of continuously received visual information

Caplette, L.; Ince, R. A. A.; Jerbi, K.; Gosselin, F.

10.1101/566042 — neuroscience — Posted on 2019-03-04

3081 Polymer brush bilayers under stationary shear motion at linear response regime: A theoretical approach

Edwards, M.

10.1101/565796 — biophysics — Posted on 2019-03-04

3082 A framework for predicting soft-fruit yields and phenology using embedded, networked microsensors, coupled weather models and machine-learning techniques

Lee, M.; Monteiro, A.; Barclay, A.; Marcar, J.; Miteva-Neagu, M.; Parker, J.

10.1101/565010 — plant biology — Posted on 2019-03-04

3083 Small RNA expression pattern in multiply inbred lines and their hybrids of maize embryo

Liu, Y.-X.

10.1101/565911 — plant biology — Posted on 2019-03-04

3084 Mechanical stress initiates and sustains the morphogenesis of wavy leaf epidermal cells

Bidhendi, A. J.; Altartouri, B.; Gosselin, F.; Geitmann, A.

10.1101/563403 — plant biology — Posted on 2019-03-04

3085 On Pectin Methyl-esterification: Implications for In vitro and In vivo Viscoelasticity

Kaplan, J. L.; Torode, T. A.; Bou Daher, F.; Braybrook, S. A.

10.1101/565614 — plant biology — Posted on 2019-03-04

3086 Cryopreservation of Rosa hybrida cv. Helmut Schmidt by PVS2 vitrification method using in vitro fragmented explants (IFEs)

Subramaniam, S.; Mubbarakh, S. A.; Udain, J.; James, J. J.; Zakaria, R.

10.1101/567255 — plant biology — Posted on 2019-03-04

3087 PCH1 regulates light, temperature, and circadian signaling as a structural component of phytochrome B-photobodies in Arabidopsis

Huang, H.; McLoughlin, K.; Sorkin, M.; Burgie, E. S.; Bindbeutel, R.; Vierstra, R.; Nusinow, D.

10.1101/566687 — plant biology — Posted on 2019-03-04

3088 Value-driven attentional capture enhances distractor representations in early visual cortex

Itthipuripat, S.; Vo, V. A.; Sprague, T. C.; Serences, J.

10.1101/567354 — neuroscience — Posted on 2019-03-04

3089 B-1 cell-mediated modulation of M1-macrophage profile can ameliorate microbicidal functions and disrupt the evasion mechanisms of Encephalitozoon cuniculi

Pereira, A.; Alvares-Saraiva, A. M.; Konno, F. T. d. C.; Spadacci-Morena, D. D.; Perez, E. C.; Mariano, M.; Lallo, M. A.

10.1101/567404 — microbiology — Posted on 2019-03-04

3090 Association of Functional Variants and Protein-to-Protein Physical Interactions of Human MutY homolog linked with Familial Adenomatous Polyposis and colorectal cancer Syndrome

Abduljaleel, Z.

10.1101/552943 — genetics — Posted on 2019-03-04

3091 The AAA+ ATPase TorsinA polymerizes into hollow tubes with a helical periodicity of 8.5 subunits per turn

Demircioglu, E.; Zheng, W.; McQuown, A. J.; Maier, N.; Watson, N.; Cheeseman, I. M.; Denic, V.; Egelman, E. H.; Schwartz, T. U.

10.1101/567099 — biochemistry — Posted on 2019-03-04

3092 Caffeine but not acetaminophen increases 4-km cycling time-trial performance

Lima-Silva, A. E.; Tomazini, F.; Mariano, A. C. S.; Andrade-Souza, V. A.; Sebben, V. C.; de Maria, C. A. B.; Coelho, D. B.; Bertuzzi, R.; Silva-Cavalcante, M. D.

10.1101/567313 — physiology — Posted on 2019-03-04

3093 NOVEL ORGAN-SPECIFIC GENETIC FACTORS FOR QUANTITATIVE RESISTANCE TO LATE BLIGHT IN POTATO

Juyo Rojas, D. K.; Soto Sedano, J. C.; Ballvora, A.; Leon, J.; Mosquera Vasquez, T.

10.1101/567289 — genetics — Posted on 2019-03-04

3094 Chronic alcohol abuse affects the clinical course and outcome ofcommunity-acquired bacterial meningitis

Paciorek, M.; Bednarska, A.; Krogulec, D.; Makowiecki, M.; Kowalska, J. D.; Bursa, D.; Swiderska, A.; Puła, J.; Raczynska, J.; Skrzat-Klapaczynska, A.; Radkowski, M.; Laskus, T.; Horban, A.

10.1101/567347 — epidemiology — Posted on 2019-03-04

3095 Description and lessons learned from the 2014 Dengue outbreak in Dar es Salaam, Tanzania. Knowledge, attitudes and bite prevention practices among those with confirmed Dengue

Msellemu, D.; Gavana, T.; Ngonyani, H.; Mlacha, Y. P.; Chaki, P.; Moore, S. J.

10.1101/567396 — epidemiology — Posted on 2019-03-04

3096 Molecular evolution guided functional analyses reveals Nucleobindin-1 as a canonical E-box binding protein promoting Epithelial-to-Mesenchymal transition (EMT)

Sinha, S.; Pattnaik, S.; Aradhyam, G. K.

10.1101/566836 — cell biology — Posted on 2019-03-04

3097 Single-Cell RNA Sequencing Reveals Regulatory Mechanism for Trophoblast Cell-Fate Divergence in Human Peri-Implantation Embryo

Lv, B.; An, Q.; Zeng, Q.; Lu, P.; Zhu, X.; Ji, Y.; Fan, G.; Xue, Z.

10.1101/567362 — cell biology — Posted on 2019-03-04

3098 Exploiting evolutionary herding to control drug resistance in cancer

Acar, A.; Nichol, D.; Fernandez, J.; Cresswell, G. D.; Barozzi, I.; Hong, S. P.; Spiteri, I.; Stubbs, M.; Burke, R.; Stewart, A.; Vlachogiannis, G.; Maley, C. C.; Magnani, L.; Valeri, N.; Banerji, U.; Sottoriva, A.

10.1101/566950 — cancer biology — Posted on 2019-03-04

3099 An interplay between reaction-diffusion and cell-matrix adhesion regulates multiscale invasion in early breast carcinomatosis

Pally, D.; Pramanik, D.; Bhat, R.

10.1101/566612 — cancer biology — Posted on 2019-03-04

3100 Mouth Function Determines The Shape Oscillation Pattern In Regenerating Hydra Tissue Spheres

Wang, R.; Goel, T.; Khazoyan, K.; Sabry, Z.; Quan, H. J.; Diamond, P. H.; Collins, E.-M. S.

10.1101/565465 — biophysics — Posted on 2019-03-04

3101 Allosteric studies of an open pH gate KcsA mutant in its activated and inactivated states

Sun, Z.; Xu, Y.; Zhang, D.; McDermott, A. E.

10.1101/567024 — biophysics — Posted on 2019-03-04

3102 Sex differences in gene expression and proliferation are dependent on the epigenetic modifier HP1γ

Law, P. P.; Chan, P.-K.; McEwen, K.; Zhi, H.; Liang, B.; Chie, N.; Asano, M.; Tan-Un, K.-C.; Chan, G. C.-F.; Festenstein, R.

10.1101/563940 — developmental biology — Posted on 2019-03-04

3103 Distinct RhoGEFs activate apical and junctional actomyosin contractility under control of G proteins during epithelial morphogenesis

Garcia De Las Bayonas, A.; Philippe, J.-M.; Lellouch, A.; Lecuit, T.

10.1101/566919 — developmental biology — Posted on 2019-03-04

3104 Untangling the Evolutionary History of European Bison (Bison bonasus)

van Loenen, A. L.; Hofman-Kaminska, E.; Mitchell, K. J.; Llamas, B.; Bocherens, H.; Soubrier, J.; Heiniger, H.; Pacher, M.; Makowiecki, D.; Piliciauskiene, G.; Drucker, D.; Kowalczyk, R.; Cooper, A.

10.1101/467951 — evolutionary biology — Posted on 2019-03-04

3105 Structure-specific regulation of nutrient absorption, metabolism and transfer in arbuscular mycorrhizal fungi

Kameoka, H.; Maeda, T.; Okuma, N.; Kawaguchi, M.

10.1101/491811 — plant biology — Posted on 2019-03-03

3106 Contribution of Apical and Basal Dendrites of L2/3 Pyramidal Neurons to Orientation Encoding in Mouse V1

Park, J.; Papoutsi, A.; Ash, R. T.; Marin, M. A.; Poirazi, P.; Smirnakis, S. M.

10.1101/566588 — neuroscience — Posted on 2019-03-03

3107 Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling.

Liang, Q.; Dharmat, R.; Owen, L.; Shakoor, A.; Li, Y.; Kim, S.; Vitale, A.; Kim, I.; Morgan, D.; Wu, N.; DeAngelis, M.; Chen, R.

10.1101/468207 — genomics — Posted on 2019-03-03

3108 The Genomic Landscape of Centromeres in Cancers

Saha, A.; Mourad, M.; Kaplan, M. H.; Chefetz, I.; Malek, S. N.; Buckanovich, R.; Markovitz, D. M.; Contreras-Galindo, R.

10.1101/505800 — genomics — Posted on 2019-03-03

3109 Massive computational acceleration by using neural networks to emulate mechanism-based biological models

Wang, S.; Kai, F.; Luo, N.; Cao, Y.; Wu, F.; Zhang, C.; Heller, K. A.; You, L.

10.1101/559559 — systems biology — Posted on 2019-03-03

3110 Optical imaging of single protein size, charge, mobility, binding and conformational change

Ma, G.; Zhu, H.; Wan, Z.; Yang, Y.; Wang, S.; Tao, N.

10.1101/505404 — biophysics — Posted on 2019-03-03

3111 Galanin neurons in the hypothalamus link sleep homeostasis, body temperature and actions of the alpha2 adrenergic agonist dexmedetomidine

Ma, Y.; Miracca, G.; Yu, X.; Harding, E. C.; Miao, A.; Yustos, R.; Vyssotski, A. L.; Franks, N. P.; Wisden, W.

10.1101/565747 — neuroscience — Posted on 2019-03-03

3112 Genomic decoding of neuronal depolarization by stimulus-specific NPAS4 heterodimers

Brigidi, G. S.; Hayes, M. G. B.; Hartzell, A. L.; Texari, L.; Lin, P.-A.; Bartlett, A.; Ecker, J. R.; Benner, C.; Heinz, S.; Bloodgood, B. L.

10.1101/565721 — neuroscience — Posted on 2019-03-03

3113 Structured Inhibitory Activity Dynamics During Learning

Arriaga, M.; Han, E. B.

10.1101/566257 — neuroscience — Posted on 2019-03-03

3114 How helpful are the protein-protein interaction databases and which ones?

Bajpai, A. K.; Davuluri, S.; Tiwary, K.; Narayanan, S.; Oguru, S.; Basavaraju, K.; Dayalan, D.; Thirumurugan, K.; Acharya, K. K.

10.1101/566372 — bioinformatics — Posted on 2019-03-03

3115 Social status in mouse social hierarchies is associated with variation in oxytocin and vasopressin 1a receptor densities

Lee, W.; Hiura, L.; Yang, E.; Broekman, K. A.; Ophir, A. G.; Curley, J.

10.1101/566067 — neuroscience — Posted on 2019-03-03

3116 Differential in vivo biodistribution of 131I-labeled exosomes from diverse cellular origins and its implication in the theranostic application.

Rashid, M. H.; Borin, T. F.; Ara, R.; Angara, K.; Cai, J.; Achyut, B.; Liu, Y.; Arbab, A. S.

10.1101/566323 — cancer biology — Posted on 2019-03-03

3117 Rho-dependent control of the Citron kinase, Sticky, drives midbody ring maturation.

El-amine, N.; Carim, S. C.; Wernike, D.; Hickson, G. R.

10.1101/566463 — cell biology — Posted on 2019-03-03

3118 Programmable Modulation for Extracellular Vesicles

Wang, Y.; Melvin, R.; Bemis, L. T.; Worrell, G. A.; Wang, H.-L.

10.1101/566448 — neuroscience — Posted on 2019-03-03

3119 The Marginal Cells of the Caenorhabditis elegans Pharynx Scavenge Cholesterol and Other Hydrophobic Small Molecules

Kamal, M.; Moshiri, H.; Magomedova, L.; Han, D.; Nguyen, K. C.; Yeo, M.; Knox, J.; Bagg, R.; Won, A. M.; Szlapa, K.; Yip, C.; Cummins, C. L.; Hall, D. H.; Roy, P. J.

10.1101/565473 — developmental biology — Posted on 2019-03-03

3120 Systematic identification of regulators of antibody-drug conjugate toxicity using CRISPR-Cas9 screens

Tsui, C. K.; Barfield, R. M.; Fischer, C. R.; Morgens, D. W.; Li, A.; Smith, B. A. H.; Bertozzi, C. R.; Rabuka, D.; Bassik, M. C.

10.1101/557454 — cancer biology — Posted on 2019-03-03

3121 Radiation resistant cancer cells enhance the survival and resistance of sensitive cells in prostate spheroids

Kannan, P.; Paczkowski, M.; Miar, A.; Owen, J.; Kretzschmar, W. W.; Lucotti, S.; Kaeppler, J.; Chen, J.; Markelc, B.; Kunz-Schughart, L. A.; Harris, A. L.; Partridge, M.; Byrne, H.

10.1101/564724 — cancer biology — Posted on 2019-03-03

3122 A Complex Interplay of Anionic Phospholipid Binding Regulates 3-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation

De Las Heras, G.; Calleja, V.; Bailly, R.; Dessolin, J.; Requejo-Isidro, J.; Larijani, B.

10.1101/566430 — biophysics — Posted on 2019-03-03

3123 A Framework for Collective Behavior in Plant Inspired Growth-Driven Systems, Based on Kinematics of Allotropism

Bastien, R.; Porat, A.; Meroz, Y.

10.1101/566364 — biophysics — Posted on 2019-03-03

3124 Influenza A matrix protein M1 is sufficient to induce lipid membrane deformation

Dahmani, I.; Ludwig, K.; Chiantia, S.

10.1101/565952 — biophysics — Posted on 2019-03-03

3125 Machine learning-guided channelrhodopsin engineering enables minimally-invasive optogenetics

Bedbrook, C. N.; Yang, K. K.; Robinson, J. E.; Gradinaru, V.; Arnold, F. H.

10.1101/565606 — bioengineering — Posted on 2019-03-03

3126 Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1

Poganik, J. R.; Long, M. J.; Disare, M. T.; Liu, X.; Chang, S.-H.; Hla, T.; Aye, Y.

10.1101/565937 — biochemistry — Posted on 2019-03-03

3127 Vimentin protects the structural integrity of the nucleus and suppresses nuclear damage caused by large deformations

Patteson, A. E.; Vahabikashi, A.; Pogoda, K.; Adam, S. A.; Goldman, A.; Goldman, R.; Janmey, P.

10.1101/566174 — cell biology — Posted on 2019-03-03

3128 RanBP2/Nup358 enhances RNAi activity by sumoylating and stabilizing Argonaute 1

Shen, Q.; Mathew, T.; Mahadevan, K.; Wang, Y. E.; Wu, J. Z.; Palazzo, A. F.

10.1101/555896 — molecular biology — Posted on 2019-03-03

3129 Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: Insights from accelerated molecular dynamics simulations

Bueren-Calabuig, J. A.; Bage, M.; Cowling, V. H.; Pisliakov, A. V.

10.1101/558502 — biophysics — Posted on 2019-03-03

3130 Sensitive determination of proteolytic proteoforms in limited microscale proteome samples

Weng, S. S. H.; Demir, F.; Ergin, E. K.; Dirnberger, S.; Uzozie, A.; Tuscher, D.; Nierves, L.; Tsui, J.; Huesgen, P. F.; Lange, P. F.

10.1101/566109 — biochemistry — Posted on 2019-03-03

3131 MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis

qiu, h.; Chen, F.; Chen, M.

10.1101/566224 — cancer biology — Posted on 2019-03-03

3132 Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma

Thomaz, A.; Pinheiro, K. d. V.; Souza, B. K.; Gregianin, L.; Brunetto, A. L.; Brunetto, A. T.; de Farias, C. B.; Jaeger, M. d. C.; Ramaswamy, V.; Nor, C.; Taylor, M. D.; Roesler, R.

10.1101/566000 — cancer biology — Posted on 2019-03-03

3133 Computational Design of Myristoylated Cell Penetrating Peptides Targeting Oncogenic K-Ras.G12D at the Effector Binding Membrane Interface

Li, Z.; Buck, M.

10.1101/565945 — biophysics — Posted on 2019-03-03

3134 Digital removal of autofluorescence from microscopy images

Baharlou, H.; Canete, N. P.; Bertram, K. M.; Sandgren, K. J.; Cunningham, A. L.; Harman, A. N.; Patrick, E.

10.1101/566315 — bioinformatics — Posted on 2019-03-03

3135 C-type lectins CTL4 and CTLMA2: conserved heterodimeric structure and glycan specificity in Anopheles mosquitoes

Bishnoi, R.; Contet, A.; Day, C. J.; Hou, D. C.-F.; Profitt, L. A.; Singla, D.; Sousa, G. L.; Jennings, M. P.; Povelones, M.; Valentine, A. M.; Baxter, R. H. G.

10.1101/565705 — biochemistry — Posted on 2019-03-03

3136 Adrenergic signaling in muscularis macrophages limits neuronal death following enteric infection

Matheis, F.; Muller, P. A.; Graves, C. L.; Gabanyi, I.; Kerner, Z. J.; Costa-Borges, D.; Mucida, D.

10.1101/556340 — immunology — Posted on 2019-03-03

3137 Epithelial retinoic acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity

Gattu, S.; Bang, Y.-J.; Pendse, M.; Dende, C.; Chara, A. L.; Harris, T. A.; Wang, Y.; Ruhn, K. A.; Kuang, Z.; Sockanathan, S.; Hooper, L. V.

10.1101/563908 — immunology — Posted on 2019-03-03

3138 Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre PBR28 HRRT PET study

Tuisku, J.; Plaven-Sigray, P.; Gaiser, E. C.; Airas, L.; Al-Abdulrasul, H.; Brück, A.; Carson, R. E.; Chen, M.-K.; Cosgrove, K. P.; Ekblad, L.; Esterlis, I.; Farde, L.; Forsberg, A.; Halldin, C.; Helin, S.; Kosek, E.; Lekander, M.; Lindgren, N.; Marjamäki, P.; Rissanen, E.; Sucksdorff, M.; Varrone, A.; HRRT [11C]PBR28 study group, ; Rinne, J.; Matuskey, D.; Cervenka, S.

10.1101/564831 — immunology — Posted on 2019-03-03

3139 Beyond Core Object Recognition: Recurrent processes account for object recognition under occlusion

Rajaei, K.; Mohsenzadeh, Y.; Ebrahimpour, R.; Khaligh-Razavi, S.-M.

10.1101/302034 — neuroscience — Posted on 2019-03-03

3140 Wnt activator FOXB2 drives prostate cancer neuroendocrine differentiation

Moparthi, L.; Pizzolato, G.; Koch, S.

10.1101/564625 — cancer biology — Posted on 2019-03-03

3141 Natural variation in the roles of C. elegans autophagy components during microsporidia infection

Balla, K.; Lazetic, V.; Troemel, E.

10.1101/418749 — immunology — Posted on 2019-03-03

3142 Flv1-4 proteins function in versatile combinations in O2 photoreduction in cyanobacteria

Santana Sanchez, A. I.; Solymosi, D.; Mustila, H.; Bersanini, L.; Aro, E.-M.; Allahverdiyeva, Y.

10.1101/561456 — biochemistry — Posted on 2019-03-03

3143 Tailoring 3D cell culture templates with common hydrogels.

Pasturel, A.; Strale, P.-O.; Studer, V.

10.1101/370882 — bioengineering — Posted on 2019-03-03

3144 Bridging the gap between single-cell migration and collective dynamics

Thüroff, F.; Goychuk, A.; Reiter, M.; Frey, E.

10.1101/548677 — biophysics — Posted on 2019-03-02

3145 Splice junction centric approach to identify translated noncanonical isoforms in the human proteome

Lau, E.; Han, Y.; Lam, M. P. Y.

10.1101/372995 — systems biology — Posted on 2019-03-02

3146 A Monte Carlo method for in silico modeling and visualization of Waddington's epigenetic landscape with intermediate details

Zhang, X.; Chong, K. H.; Zheng, J.

10.1101/310771 — systems biology — Posted on 2019-03-02

Hage, R.; Dierick, F.; Roussel, N.; Pitance, L.; Detrembleur, C.

10.1101/519488 — physiology — Posted on 2019-03-02

3148 The influence of fluctuating population densities on evolutionary dynamics

Pisa, H.; Hermisson, J.; Polechova, J.

10.1101/444273 — evolutionary biology — Posted on 2019-03-02

3149 A quantitative genetics approach to the evolution of phenotypic (co)variance under limited dispersal, with an application to socially synergistic traits

Mullon, C.; Lehmann, L.

10.1101/393538 — evolutionary biology — Posted on 2019-03-02

3150 HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness Phenotype in Medulloblastoma

Jaeger, M. d. C.; Ghisleni, E. C.; Cardoso, P. S.; Siniglaglia, M.; Falcon, T.; Brunetto, A. T.; Brunetto, A. L.; de Farias, C. B.; Taylor, M. D.; Nor, C.; Ramaswamy, V.; Roesler, R.

10.1101/521393 — cancer biology — Posted on 2019-03-02

3151 Global transcriptome analysis of the Myxococcus xanthus multicellular developmental program

Munoz-Dorado, J.; Moraleda-Munoz, A.; Marcos-Torres, F. J.; Contreras-Moreno, F. J.; Martin-Cuadrado, A. B.; Schrader, J. M.; Higgs, P. I.; Perez, J.

10.1101/564641 — microbiology — Posted on 2019-03-02

3152 Analysis on epidemiological characteristics of 4 species natural-focal diseases in Shandong Province, China in 2009-2017: a descriptive analysis

Chen, R.; Kou, Z.; Xu, L.; Cao, J.; Liu, Z.; Wen, X.; Wang, Z.; hongling, W.

10.1101/564971 — epidemiology — Posted on 2019-03-02

3153 Scans of the MYC mRNA reveal multiple stable secondary structures—including a 3′ UTR motif, conserved across vertebrates, that can affect gene expression.

O'Leary, C.; Andrews, R.; Tompkins, V.; Chen, J.; Childs-Disney, J.; Disney, M.; Moss, W. N.

10.1101/564864 — bioinformatics — Posted on 2019-03-02

3154 Compositional Data Analysis is necessary for simulating and analyzing RNA-Seq data

McGee, W. A.; Pimentel, H.; Pachter, L.; Wu, J. Y.

10.1101/564955 — bioinformatics — Posted on 2019-03-02

3155 Syndecan-1 facilitates breast cancer metastasis to the brain

10.1101/565648 — cancer biology — Posted on 2019-03-02

3156 Relating brain connectivity with persistent symptoms in pediatric concussion

Iyer, K. K.; Barlow, K. M.; Brooks, B.; Ofoghi, Z.; Zalesky, A.; Cocchi, L.

10.1101/539825 — neuroscience — Posted on 2019-03-02

3157 Fingerprinting Adiposity and Metabolic Function in the Brains of Overweight and Obese Humans

Farruggia, M. C.; van Kooten, M. J.; Burke, M. V.; Scheinost, D.; Constable, R. T.; Small, D. M.

10.1101/540997 — neuroscience — Posted on 2019-03-01

3158 Field application of an eDNA assay for the endangered white-clawed crayfish Austropotamobius pallipes

Atkinson, S.; Carlsson, J. E. L.; Ball, B.; Kelly-Quinn, M.; Carlsson, J.

10.1101/562710 — genetics — Posted on 2019-03-01

3159 A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance

Boyer, N. P.; McCormick, L. E.; Urbina, F. L.; Gupton, S.

10.1101/529222 — cell biology — Posted on 2019-03-01

3160 Conditional approach as cooperation in predator inspection: a role for serotonin?

Pimentel, A. F. N.; Carvalho, T. d. S.; Lima, F.; Lima-Maximino, M. G.; Soares, M. C.; Maximino, C.

10.1101/436345 — animal behavior and cognition — Posted on 2019-03-01

3161 Measuring phenotypic heterogeneity in isogenic bacterial populations using flow cytometry and Raman spectroscopy

Garcia-Timermans, C.; Rubbens, P.; Heyse, J.; Props, R.; Kerckhof, F.-M.; Skirtach, A.; Waegeman, W.; Boon, N.

10.1101/545681 — bioengineering — Posted on 2019-03-01

3162 A Novel Ensemble-Based Machine Learning Algorithm To Predict The Conversion From Mild Cognitive Impairment To Alzheimer's Disease Using Socio-demographic Characteristics, Clinical Information And Neuropsychological Measures

Grassi, M.; Rouleaux, N.; Caldirola, D.; Loewenstein, D.; Schruers, K.; Perna, G.; Dumontier, M.

10.1101/564716 — neuroscience — Posted on 2019-03-01

3163 Low dimensional dynamics for working memory and time encoding

Cueva, C. J.; Marcos, E.; Saez, A.; Genovesio, A.; Jazayeri, M.; Romo, R.; Salzman, C. D.; Shadlen, M. N.; Fusi, S.

10.1101/504936 — neuroscience — Posted on 2019-03-01

3164 Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis

Berry, J.-L.; Gurung, I.; Anonsen, J. H.; Spielman, I.; Harper, E.; Hall, A. M. J.; Goosens, V. J.; Raynaud, C.; Koomey, M.; Biais, N.; Matthews, S.; Pelicic, V.

10.1101/459388 — microbiology — Posted on 2019-03-01

3165 Pan-Cancer and Single-Cell modelling of genomic alterations through gene expression

Mercatelli, D.; Ray, F.; Giorgi, F. M.

10.1101/492561 — systems biology — Posted on 2019-03-01

3166 Association between development of early cortical activity on amplitude-integrated EEG and 5-years neurodevelopmental outcome in the preterm infant

Feldmann, M.; Rousson, V.; Nguyen, T. D.; Bernet, V.; Hagmann, C.; Latal, B.; Natalucci, G.

10.1101/562488 — neuroscience — Posted on 2019-03-01

3167 A lineage-resolved molecular atlas of C. elegans embryogenesis at single cell resolution

Packer, J. S.; Zhu, Q.; Huynh, C.; Sivaramakrishnan, P.; Preston, E.; Dueck, H.; Stefanik, D.; Tan, K.; Trapnell, C.; Kim, J.; Waterston, R. H.; Murray, J. I.

10.1101/565549 — genomics — Posted on 2019-03-01

3168 The alternative reality of plant mitochondrial DNA

Kozik, A.; Rowan, B.; Lavelle, D.; Berke, L.; Schranz, M. E.; Michelmore, R. W.; Christensen, A. C.

10.1101/564278 — genomics — Posted on 2019-03-01

3169 Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin

Auslander, N.; Heselmeyer-Haddad, K.; Patkar, S.; Hirsch, D.; Camps, J.; Brown, M.; Bronder, D.; Chen, W.-D.; Lokanga, R.; Wangsa, D.; Wangsa, D.; Hu, Y.; Lischka, A.; Braun, R.; Emons, G.; Ghadimi, B. M.; Gaedcke, J.; Grade, M.; Montagna, C.; Lazebnik, Y.; Difilippantonio, M. J.; Habermann, J. K.; Auer, G.; Ruppin, E.; ried, t.

10.1101/563858 — cancer biology — Posted on 2019-03-01

3170 Environmental plasticity and colonisation history in the Atlantic salmon microbiome: a translocation experiment

Uren Webster, T.; Rodriguez Barreto, D.; Castaldo, G.; Taylor, J.; Gough, P.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/564104 — microbiology — Posted on 2019-03-01

3171 Uncovering the role of admixture in disease and drug response: Association of hepatocyte gene expression and DNA methylation with African Ancestry in African Americans.

Park, S. C.; De, T.; Xu, Y.; Zhoug, Y.; Gamazon, E.; Alarcon, C.; Perera, M.

10.1101/491225 — genomics — Posted on 2019-03-01

3172 Heterozygous missense RAD21 variant in a peripheral sclerocornea pedigree

Zhang, B. N.; Chan, T. C. Y.; Tam, P. O. S.; Liu, Y.; Pang, C. P.; Jhanji, V.; Chen, L. J.; Chu, W. K.

10.1101/547547 — genetics — Posted on 2019-03-01

3173 Molecular evolution in small steps under prevailing negative selection - A nearly-universal rule of codon substitution

Chen, Q.; Lan, A.; Shen, X.; Wu, C.-I.

10.1101/510735 — evolutionary biology — Posted on 2019-03-01

3174 The UCSC Xena Platform for cancer genomics data visualization and interpretation

Goldman, M.; Craft, B.; Hastie, M.; Repecka, K.; Kamath, A.; McDade, F.; Rogers, D.; Brooks, A. N.; Zhu, J.; Haussler, D.

10.1101/326470 — cancer biology — Posted on 2019-03-01

3175 Patterns, Profiles, and Parsimony: dissecting transcriptional signatures from minimal single-cell RNA-seq output with SALSA

Lozoya, O. A.; McClelland, K. S.; Papas, B.; Li, J.-L.; Yao, H. H.-C.

10.1101/551762 — bioinformatics — Posted on 2019-03-01

3176 Fundamental bounds on learning performance in neural circuits

Raman, D. V.; O'Leary, T.

10.1101/508994 — neuroscience — Posted on 2019-03-01

3177 The Genomic Landscape of Centromeres in Cancers

Saha, A.; Mourad, M.; Kaplan, M. H.; Chefetz, I.; Malek, S. N.; Buckanovich, R.; Markovitz, D. M.; Contreras-Galindo, R.

10.1101/505800 — genomics — Posted on 2019-03-01

3178 Genomic analysis reveals a functional role for myocardial trabeculae in adults

Meyer, H. V.; Dawes, T. J.; Serrani, M.; Bai, W.; Tokarczuk, P.; Cai, J.; de Marvao, A.; Rueckert, D.; Matthews, P. M.; Costantino, M. L.; Birney, E.; Cook, S. A.; O'Regan, D. P.

10.1101/553651 — genomics — Posted on 2019-03-01

3179 Mapping drinking water and quality of life aspects in urban settings: a proof-of-concept study on the application of the urban exposome framework

Andrianou, X. D.; van der Lek, C.; Charisiadis, P.; Ioannou, S.; Fotopoulou, K. N.; Papapanagiotou, Z.; Botsaris, G.; Beumer, C.; Makris, K. C.

10.1101/401927 — epidemiology — Posted on 2019-03-01

3180 Salicylate increases fitness cost associated with MarA-mediated antibiotic resistance

Wang, T.; Kunze, C.; Dunlop, M. J.

10.1101/454983 — systems biology — Posted on 2019-03-01

3181 Binding specificities of human RNA binding proteins towards structured and linear RNA sequences

Jolma, A.; Zhang, J.; Mondragon, E.; Kivioja, T.; Yin, Y.; Zhu, F.; Morris, Q.; Hughes, T. R.; Maher, L. J.; Taipale, J.

10.1101/317909 — genomics — Posted on 2019-03-01

3182 Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly

Lamson, A.; Edelmaier, C.; Glaser, M. A.; Betterton, M.

10.1101/419135 — cell biology — Posted on 2019-03-01

3183 EECoG-Comp: An Open Source Platform for Concurrent EEG/ECoG Comparisons: applications to connectivity stuides

Wang, Q.; Valdes-Hernandez, P. A.; Paz-Linares, D.; Bosch-Bayard, J.; Oosugi, N.; Komatsu, M.; Fujii, N.; Valdes-Sosa, P. A.

10.1101/350199 — bioinformatics — Posted on 2019-03-01

3184 Best Prediction of the Additive Genomic Variance in Random-Effects Models

Schreck, N.; Piepho, H.-P.; Schlather, M.

10.1101/282343 — genomics — Posted on 2019-03-01

3185 A Stochastic Model for Cancer Metastasis: Branching Stochastic Process with Settlement

Frei, C.; Hillen, T.; Rhodes, A.

10.1101/294157 — cancer biology — Posted on 2019-03-01

3186 Choice history biases subsequent evidence accumulation

Urai, A. E.; de Gee, J. W.; Tsetsos, K.; Donner, T. H.

10.1101/251595 — neuroscience — Posted on 2019-03-01

3187 A state-dependent mean-field formalism to model different activity states in conductance based networks of spiking neurons

Capone, C.; di Volo, M.; Romagnoni, A.; Mattia, M.; Destexhe, A.

10.1101/565127 — neuroscience — Posted on 2019-03-01

3188 Network resonance during slow-wave sleep facilitates memory consolidation through phase-coding

Skilling, Q.; Clawson, B. C.; Eniwaye, B.; Shaver, J.; Ognjanovski, N.; Atan, S. J.; Zochowski, M.

10.1101/565242 — neuroscience — Posted on 2019-03-01

3189 Translation enhancement by a Dictyostelium gene sequence in Escherichia coli

Kondo, T.; Yumura, S.

10.1101/564815 — microbiology — Posted on 2019-03-01

3190 Epithelial retinoid acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity

Gattu, S.; Bang, Y.-J.; Pendse, M.; Dende, C.; Chara, A. L.; Harris, T. A.; Wang, Y.; Ruhn, K. A.; Kuang, Z.; Sockanathan, S.; Hooper, L. V.

10.1101/563908 — immunology — Posted on 2019-03-01

3191 Exon-mediated activation of transcription starts

Fiszbein, A.; Krick, K. S.; Burge, C. B.

10.1101/565184 — genomics — Posted on 2019-03-01

3192 TGF-β family ligands exhibit distinct signaling dynamics that are driven by receptor localization

Miller, D. S. J.; Schmierer, B.; Hill, C. S.

10.1101/565416 — cell biology — Posted on 2019-03-01

3193 A Mathematical Model for the Immune-Mediated Theory of Metastasis

Rhodes, A.; Hillen, T.

10.1101/565531 — cancer biology — Posted on 2019-03-01

3194 Prediction of condition-specific regulatory maps in Arabidopsis using integrated genomic data

Song, Q.; Lee, J.; Akter, S.; Grene, R.; Li, S.

10.1101/565119 — bioinformatics — Posted on 2019-03-01

3195 A stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering

Tang, J. D.; Mura, C.; Lampe, K. J.

10.1101/565317 — bioengineering — Posted on 2019-03-01

3196 Molecular Phenotyping of Oxidative Stress in Diabetes Mellitus with Point-of-care NMR system

Peng, W. K.; Chen, L.; Boehm, B. O.; Han, J.; Loh, T. P.

10.1101/565325 — bioengineering — Posted on 2019-03-01

3197 Temporal Metrics of Multisensory Processing Change in the Elderly

Basharat, A.; Barnett-Cowan, M.; Mahoney, J. R.

10.1101/565507 — neuroscience — Posted on 2019-03-01

3198 Replay as wavefronts and theta sequences as bump oscillations in a grid cell attractor network

Kang, L.; DeWeese, M. R.

10.1101/565440 — neuroscience — Posted on 2019-03-01

3199 Structural basis of the differential binding of engineered knottins 2.5F and 2.5D to integrins αVβ3 and α5β1

van Agthoven, J. F.; Shams, H.; Cochran, F. V.; Alonso, J. L.; Kintzing, J. R.; Grakami, K.; Xiong, J.-P.; Mofrad, M. R.; Cochran, J. R.; Arnaout, M. A.

10.1101/565358 — molecular biology — Posted on 2019-03-01

3200 Low-dose antibiotics can collapse gut bacterial populations via a gelation transition

Schlomann, B. H.; Wiles, T. J.; Wall, E. S.; Guillemin, K.; Parthasarathy, R.

10.1101/565556 — microbiology — Posted on 2019-03-01

3201 Sphingomyelin is critical in organizing phosphoinositide dynamics during phagocytic uptake of Mycobacterium tuberculosis.

Niekamp, P.; Guzman, G.; Leier, H.; Rashidfarrokhi, A.; Richina, V.; Holthuis, J.; Tafesse, F. G.

10.1101/565226 — microbiology — Posted on 2019-03-01

3202 Antibiotic resistome and microbial community structure during anaerobic co-digestion of food waste, paper and cardboard

Kanger, K.; Guilford, N. G. H.; Lee, H. P.; Nesbo, C. L.; Truu, J.; Edwards, E. A.

10.1101/564823 — microbiology — Posted on 2019-03-01

3203 Signatures of divergent antimalarial treatment responses in peripheral blood from infants and adults in Malawi

Maurizio, P. L.; Fuseini, H.; Tegha, G.; Hosseinipour, M.; De Paris, K.

10.1101/564757 — immunology — Posted on 2019-03-01

3204 The DNA Methylome of Inflammatory Bowel Disease (IBD) reflects intrinsic and extrinsic factors in intestinal epithelial cells

Agliata, I.; Fernandez-Jimenez, N.; Goldsmith, C.; Marie, J. C.; Bilbao, J. R.; Dante, R.; Hernandez-Vargas, H.

10.1101/565200 — genomics — Posted on 2019-03-01

3205 A nematode-specific gene underlies bleomycin-response variation in Caenorhabditis elegans

Brady, S. C.; Zdraljevic, S.; Bisaga, K. W.; Tanny, R. E.; Cook, D. E.; Lee, D.; Wang, Y.; Andersen, E. C.

10.1101/565218 — genetics — Posted on 2019-03-01

3206 Evolutionary analyses unveil the molecular mechanism of fast inactivation in calcium-permeable TRP channels

Flores-Aldama, L.; Vandewege, M.; Zavala, K.; Colenso, C.; Bustos, D.; Gonzalez, W.; Brauchi, S.; Opazo, J. C.

10.1101/564997 — evolutionary biology — Posted on 2019-03-01

3207 Consequences of recombination for the evolution of the mating type locus in Chlamydomonas reinhardtii

Hasan, A. R.; Duggal, J. K.; Ness, R. W.

10.1101/565275 — evolutionary biology — Posted on 2019-03-01

3208 Top-down and bottom-up controls on soil carbon and nitrogen cycling with repeated burning across four ecosystems

Pellegrini, A. F. A.; Hobbie, S. E.; Reich, P. B.; Jumpponen, A.; Brookshire, E. N. J.; Caprio, A. C.; Coetsee, C.; Jackson, R. B.

10.1101/565135 — ecology — Posted on 2019-03-01

3209 Supercharged Assembly: A Broad-Spectrum Mechanism of Action for Drugs that Undermine Controlled HIV-1 Viral Capsid Formation

Pak, A. J.; Grime, J. M. A.; Yu, A.; Voth, G. A.

10.1101/565515 — biophysics — Posted on 2019-03-01

3210 Robust Determination of Protein Allosteric Signaling Pathways

Luo, Y.; Botello-Smith, W.

10.1101/565457 — biophysics — Posted on 2019-03-01

3211 The size of the immune repertoire of bacteria

Bradde, S.; Nourmohammad, A.; Goyal, S.; Balasubramanian, V.

10.1101/565366 — biophysics — Posted on 2019-03-01

3212 Mash Screen: High-throughput sequence containment estimation for genome discovery

Ondov, B. D.; Starrett, G. J.; Sappington, A.; Kostic, A.; Koren, S.; Buck, C. B.; Phillippy, A. M.

10.1101/557314 — bioinformatics — Posted on 2019-03-01

3213 The DNA-binding protein HTa from Thermoplasma acidophilum is an archaeal histone analog

Hocher, A.; Rojec, M.; Swadling, J. B.; Esin, A.; Warnecke, T.

10.1101/564930 — microbiology — Posted on 2019-03-01

3214 Shotgun proteomics analysis of nanoparticle-synthesising Desulfovibrio alaskensis in response to platinum and palladium

Capeness, M.; Imrie, L.; Muhlbauer, L. F.; Le Bihan, T.; Horsfall, L. E.

10.1101/565036 — microbiology — Posted on 2019-03-01

3215 A lineage-resolved molecular atlas of C. elegans embryogenesis at single cell resolution

Packer, J. S.; Zhu, Q.; Huynh, C.; Sivaramakrishnan, P.; Preston, E.; Dueck, H.; Stefanik, D.; Tan, K.; Trapnell, C.; Kim, J.; Waterston, R. H.; Murray, J. I.

10.1101/565549 — genomics — Posted on 2019-03-01

3216 New transcriptional circuit evolved by coding sequence changes in a master regulator followed by cis-regulatory changes in its target genes

Britton, C. S.; Sorrells, T. R.; Johnson, A. D.

10.1101/565234 — evolutionary biology — Posted on 2019-03-01

3217 Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions

Blasco, A.; Endres, M. G.; Sergeev, R. A.; Jonchhe, A.; Macaluso, M.; Narayan, R.; Natoli, T.; Paik, J. H.; Briney, B.; Wu, C.; Su, A. I.; Subramanian, A.; Lakhani, K. R.

10.1101/565481 — bioinformatics — Posted on 2019-03-01

3218 Avant-garde: An automated data-driven DIA data curation tool.

Vaca Jacome, A. S.; Peckner, R.; Shulman, N.; Krug, K.; DeRuff, K. C.; Officer, A.; MacLean, B.; MacCoss, M. J.; Carr, S. A.; Jaffe, J. D.

10.1101/565523 — bioinformatics — Posted on 2019-03-01

3219 Body-map proto-organization in newborn macaques

Arcaro, M.; Schade, P. F.; Livingstone, M. S.

10.1101/565390 — neuroscience — Posted on 2019-03-01

3220 Learning what is irrelevant or relevant: Expectations facilitate distractor inhibition and target facilitation through distinct neural mechanisms

van Moorselaar, D.; Slagter, H.

10.1101/565069 — neuroscience — Posted on 2019-03-01

3221 Developmental Recovery of Impaired Multisensory Processing in Autism and the Cost of Switching Sensory Modality

Crosse, M. J.; Foxe, J. J.; Molholm, S.

10.1101/565333 — neuroscience — Posted on 2019-03-01

3222 Zebrafish (Danio rerio) behavioral laterality predicts increased short-term avoidance memory but not stress-reactivity responses

Dotto Fontana, B.; Cleal, M.; Clay, J.; Parker, M. O.

10.1101/565309 — animal behavior and cognition — Posted on 2019-03-01

3223 The Development of Optimally Responsive Plasmodium-specific CD73+CD80+ IgM+ Memory B cells Requires Intrinsic BCL6 expression but not CD4+ Tfh cells

Pritchard, G. H.; Krishnamurty, A. T.; Netland, J.; Arroyo, E. N.; Takehara, K. K.; Pepper, M.

10.1101/564351 — immunology — Posted on 2019-03-01

3224 A single dose of dietary nitrate increases maximal muscle speed and power in healthy older men and women

Coggan, A. R.; Hoffman, R. L.; Gray, D. A.; Moorthi, R. N.; Thomas, D. P.; Leibowitz, J. L.; Thies, D.; Peterson, L. R.

10.1101/564849 — physiology — Posted on 2019-03-01

3225 Short-term depression and long-term plasticity together tune sensitive range of synaptic plasticity

Deperrois, N.; Graupner, M.

10.1101/565291 — neuroscience — Posted on 2019-03-01

3226 Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre PBR28 HRRT PET study

Tuisku, J.; Plaven-Sigray, P.; Gaiser, E. C.; Airas, L.; Al-Abdulrasul, H.; Bruck, A.; Carson, R. E.; Chen, M.-K.; Cosgrove, K. P.; Ekblad, L.; Esterlis, I.; Farde, L.; Forsberg, A.; Halldin, C.; Helin, S.; Kosek, E.; Lekander, M.; Lindgren, N.; Marjamaki, P.; Rissanen, E.; Sucksdorff, M.; Varrone, A.; HRRT [11C]PBR28 study group, ; Rinne, J.; Matuskey, D.; Cervenka, S.

10.1101/564831 — immunology — Posted on 2019-03-01

3227 Genetic inhibition of PCSK9, atherogenic lipoprotein concentrations, and calcific aortic valve stenosis

Perrot, N.; Moschetta, D.; Boekholdt, M.; Valerio, V.; Martinsson, A.; Capoulade, R.; Mass, E.; Clavel, M.-A.; Wareham, N. J.; Dina, C.; Chen, H. Y.; Engert, J. C.; Thanassoulis, G.; Mathieu, P.; Bosse, Y.; Pibarot, P.; Smith, J. G.; Camera, M.; Theriault, S.; Poggio, P.; Arsenault, B. J.

10.1101/560458 — genetics — Posted on 2019-03-01

3228 A pleiotropic role for FGF signaling in mammary gland stromal fibroblasts

Koledova, Z.; Sumbal, J.

10.1101/565267 — developmental biology — Posted on 2019-03-01

3229 A smooth muscle-like niche facilitates lung epithelial regeneration

Moiseenko, A.; Vazquez-Armendariz, A. I.; Chu, X.; Guenther, S.; Lebrigand, K.; Kheirollahi, V.; Herold, S.; Braun, T.; Mari, B.; De Langhe, S.; Chen, C.; Li, X.; Seeger, W.; Zhang, J.-S.; Bellusci, S.; El Agha, E.

10.1101/565085 — developmental biology — Posted on 2019-03-01

3230 A novel growth factor-dependent thermogenic brown adipocyte cell line from defined precursor cells

Kindler, D.; Sousa, I. S.; Schweizer, S.; Lerch, S.; Klingenspor, M.; Herzig, S.; Vegiopoulos, A.

10.1101/565168 — cell biology — Posted on 2019-03-01

3231 Pair-wise Comparison Analysis for Multiple Pool-sep: an efficient method identified anthocyanin biosynthesis genes in rice pericarp

Yang, X.; Xia, X.; Zhang, Z.; Nong, B.; Zeng, Y.; Wu, Y.; Xiong, F.; Zhang, Y.; Liang, H.; Pan, Y.; Dai, G.; Deng, G.; Li, D.

10.1101/561258 — genomics — Posted on 2019-03-01

3232 'Candidatus Phytoplasma platensis', a novel taxon associated with daisy (Bellis perennis) virescence and related diseases in South America

Fernandez, F. D.; Galdeano, E.; Conci, L. R.

10.1101/564807 — molecular biology — Posted on 2019-03-01

3233 An Oculometrics-based Biofeedback System to Impede Fatigue Development during Computer Work: a Proof-of-Concept Study

Zargari Marandi, R.; Madeleine, P.; Vuillerme, N.; Omland, O.; Samani, A.

10.1101/563932 — physiology — Posted on 2019-03-01

3234 Estimation of neural network model parameters from local field potentials (LFPs)

Skaar, J.-E. W.; Stasik, A. J.; Hagen, E.; Ness, T. V.; Einevoll, G. T.

10.1101/564765 — neuroscience — Posted on 2019-03-01

3235 Ancestral persistence of vestibulo-spinal reflexes in axial muscles in humans

Guillaud, E.; Faure, C.; Doat, E.; Bouyer, L.; Guehl, D.; Cazalets, J.-R.

10.1101/564617 — neuroscience — Posted on 2019-03-01

3236 Active role of free RNA during the early phase of proteostasis stress

Alriquet, M.; Martinez-Limon, A.; Hanspach, G.; Hengesbach, M.; Tartaglia, G. G.; Calloni, G.; Vabulas, R. M.

10.1101/564799 — cell biology — Posted on 2019-03-01

3237 Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin

10.1101/563858 — cancer biology — Posted on 2019-03-01

3238 Cue-induced effects on decision-making distinguish subjects with gambling disorder from healthy controls

Genauck, A.; Andrejevic, M.; Brehm, K.; Matthis, C.; Heinz, A.; Weinreich, A.; Kathmann, N.; Romanczuk-Seiferth, N.

10.1101/564781 — neuroscience — Posted on 2019-03-01

3239 Salmonella genomic island 3 is an integrative and conjugative element and contributes to copper and arsenic resistance of Salmonella enterica

Arai, N.; Sekizuka, T.; Tamamura, Y.; Kusumoto, M.; Hinenoya, A.; Yamasaki, S.; Iwata, T.; Watanabe-Yanai, A.; Kuroda, M.; Akiba, M.

10.1101/564534 — microbiology — Posted on 2019-03-01

3240 Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissues-of-origin

Liu, Y.; Liu, T.-Y.; Weinberg, D. E.; White, B. W.; De La Torre, C. J.; Tan, C. L.; Schmitt, A. D.; Selvaraj, S.; Tran, V.; Laurent, L. C.; Cabel, L.; Bidard, F.-C.; Putcha, G.; Haque, I. S.

10.1101/564773 — genomics — Posted on 2019-03-01

3241 Transcriptome Profiling of Mouse Brain and Lung under Dip2A Regulation Using RNA-Sequencing

Sah, R. K.; Anlan, Y.; Bah, F. B.; Adlat, S.; Bohio, A. A.; Oo, Z. M.; Wang, C.; Myint, M. Z. Z.; Bahadar, N.; Zhang, L.; Feng, X.; Zheng, Y.

10.1101/563916 — genetics — Posted on 2019-03-01

3242 Protein secondary structure determines the temporal relationship between folding and disulfide formation

Robinson, P.; Kanemura, S.; Cao, X.; Bulleid, N.

10.1101/564740 — biochemistry — Posted on 2019-03-01

3243 Lifespan trajectories and relationships to memory of the macro- and microstructure of the anterior and posterior hippocampus - a longitudinal multi-modal imaging study

Langnes, E.; Sneve, M. H.; Sederevicius, D.; Amlien, I. K.; Walhovd, K. B.; Fjell, A. M.

10.1101/564732 — neuroscience — Posted on 2019-03-01

3244 A Novel Ensemble-Based Machine Learning Algorithm To Predict The Conversion From Mild Cognitive Impairment To Alzheimer's Disease Using Socio-demographic Characteristics, Clinical Information And Neuropsychological Measures

Grassi, M.; Rouleaux, N.; Caldirola, D.; Loewenstein, D.; Schruers, K.; Perna, G.; Dumontier, M.

10.1101/564716 — neuroscience — Posted on 2019-03-01

3245 Neph/Nephrin-like adhesion and tissue level pulling forces regulate cell intercalation during Drosophila retina development.

Blackie, L.; Tozluoglu, M.; Trylinski, M.; Walther, R.; Mao, Y.; Schweisguth, F.; Pichaud, F.

10.1101/564708 — developmental biology — Posted on 2019-03-01

3246 Wnt activator FOXB2 drives prostate cancer neuroendocrine differentiation

Moparthi, L.; Pizzolato, G.; Koch, S.

10.1101/564625 — cancer biology — Posted on 2019-03-01

3247 Association between development of early cortical activity on amplitude-integrated EEG and 5-years neurodevelopmental outcome in the preterm infant

Feldmann, M.; Rousson, V.; Nguyen, T. D.; Bernet, V.; Hagmann, C.; Latal, B.; Natalucci, G.

10.1101/562488 — neuroscience — Posted on 2019-03-01

3248 Dopaminergic signalling is necessary, but not sufficient for cued fear memory destabilisation

Lee, J. L. C.; Flavell, C. R.

10.1101/564674 — neuroscience — Posted on 2019-03-01

3249 High-throughput genotyping of a full voltage-gated sodium channel gene via genomic DNA using target capture sequencing and analytical pipeline MoNaS to discover novel insecticide resistance mutations

Itokawa, K.; Yatsu, K.; Sekizuka, T.; Maekawa, Y.; Komagata, O.; Sugiura, M.; Sasaki, T.; Tomita, T.; Kuroda, M.; Sawabe, K.; Kasai, S.

10.1101/564609 — genetics — Posted on 2019-03-01

3250 Pluripotency factors regulate the onset of Hox cluster activation in the early embryo

10.1101/564658 — developmental biology — Posted on 2019-03-01

3251 Nanotubes effectively deliver siRNA to intact plant cells and protect siRNA against nuclease degradation

Demirer, G. S.; Zhang, H.; Goh, N. S.; Chang, R.; Landry, M. P.

10.1101/564427 — plant biology — Posted on 2019-03-01

3252 Emotion Modulation of the Body-Selective Areas in the Developing Brain

Ross, P.; de Gelder, B.; Crabbe, F.; Grosbras, M.-H.

10.1101/564633 — neuroscience — Posted on 2019-03-01

3253 Snow is an important control of plant community functional composition

Happonen, K.; Aalto, J.; Kemppinen, J.; Niittynen, P.; Virkkala, A.-M.; Luoto, M.

10.1101/564583 — ecology — Posted on 2019-03-01

3254 LonP1 Orchestrates UPRmt and UPRER and Mitochondrial Dynamics to Regulate Heart Function

Lu, B.; Shangguan, F.; Huang, D.; Gong, S.; Shi, Y.; Song, Z.; Jia, L.; Xu, J.; Yan, C.; Chen, T.; Xu, M.; Li, Y.; Han, S.; Song, N.; Chen, P.; Wang, L.; Liu, Y.; Huang, X.; Suzuki, C. K.; Yang, Z.; Yang, G.

10.1101/564492 — cell biology — Posted on 2019-03-01

3255 siRNA containing a unique 5-nucleotide motif acts as a quencher of IFI16-mediated innate immune response

Sui, H.; Yang, J.; Hu, X.; Imamichi, T.; Chen, Q.

10.1101/564872 — immunology — Posted on 2019-03-01

3256 The Microbial Metagenome and Tissue Composition in Mice with Microbiome-Induced Reductions in Bone Strength

Guss, J. D.; Taylor, E.; Rouse, Z.; Roubert, S.; Higgins, C. H.; Thomas, C. J.; Baker, S.; Vashishth, D.; Donnelly, E.; Shea, M. K.; Booth, S. L.; Bicalho, R. L.; Hernandez, C.

10.1101/562058 — bioengineering — Posted on 2019-03-01

3257 In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer

He, L.; Perrimon, N.; Binari, R.; Huang, J.; Falo, J.

10.1101/564690 — developmental biology — Posted on 2019-03-01

3258 Predicting nucleation sites in chemotaxing Dictyostelium discoideum

Asante-Asamani, E. O.; Rawal, D.; Santiago, Z.; Brazill, D.; Loustau, J.

10.1101/564963 — cell biology — Posted on 2019-03-01

3259 Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment

De Leo, F.; Quilici, G.; Tirone, M.; Mannella, V.; De Marchis, F.; Preti, A.; Gori, A.; Casalgrandi, M.; Mezzapelle, R.; Bianchi, M.; Musco, G.

10.1101/563890 — biochemistry — Posted on 2019-03-01

3260 Mannitol ingestion causes concentration-dependent, sex-specific mortality in adults of the fruit fly (Drosophila melanogaster).

Fiocca, K.; Barrett, M.; Waddell, E. A.; McNair, C.; O'Donnell, S.; Marenda, D. R.

10.1101/564898 — zoology — Posted on 2019-03-01

3261 Operating regimes in a single enzymatic cascade at ensemble-level

Parundekar, A.; Kalantre, G.; Khadpekar, A.; Viswanathan, G. A.

10.1101/564922 — systems biology — Posted on 2019-03-01

3262 Excitatory and inhibitory subnetworks are equally selective during decision-making and emerge simultaneously during learning

Najafi, F.; Elsayed, G. F.; Cao, R.; Pnevmatikakis, E.; Latham, P. E.; Cunningham, J.; Churchland, A. K.

10.1101/354340 — neuroscience — Posted on 2019-03-01

3263 Diversity patterns in parasite populations capable forpersistence and reinfection with a view towards the humancytomegalovirus

Pokalyuk, C.; Goerzer, I.

10.1101/512970 — evolutionary biology — Posted on 2019-03-01

3264 Deconvolving multiplexed protease signatures with substrate reduction and activity clustering

Zhuang, Q.; Holt, B. A.; Kwong, G. A.; Qiu, P.

10.1101/564906 — bioengineering — Posted on 2019-03-01

3265 Effective Public Apologies

Kim, H.; Kralik, J. D.; Yun, K.; Chung, Y.-a.; Jeong, J.

10.1101/564880 — neuroscience — Posted on 2019-03-01

3266 Antimicrobial susceptibility and serotype distribution of Streptococcus agalactiae recto-vaginal colonizing isolates from pregnant women at a tertiary hospital in Pretoria, South Africa: an observational descriptive study letter

Said, M.; Dangor, Y.; Mbelle, N.; Madhi, S.; Kwatra, G.; Ismail, F.

10.1101/564856 — microbiology — Posted on 2019-03-01

3267 The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs

Marchant, A.; Cisneros, A.; Dube, A.; Gagnon-Arsenault, I.; Ascencio, D.; Jain, H.; Aube, S.; Eberlein, C.; Evans-Yamamoto, D.; Yachie, N.; Landry, C.

10.1101/564401 — evolutionary biology — Posted on 2019-03-01

3268 The Development of Optimally Responsive Plasmodium-specific CD73+CD80+ IgM+ Memory B cells Requires Intrinsic BCL6 expression butnot CD4+ Tfh cells

Pritchard, G. H.; Pepper, M.; Krishnamurty, A. T.; Netland, J.; Arroyo, E. N.; Takehara, K. K.

10.1101/564351 — immunology — Posted on 2019-03-01

3269 The alternative reality of plant mitochondrial DNA

Kozik, A.; Rowan, B.; Lavelle, D.; Berke, L.; Schranz, M. E.; Michelmore, R. W.; Christensen, A. C.

10.1101/564278 — genomics — Posted on 2019-03-01

3270 RB1 deletion in RB-pathway disrupted cells results in DNA damage and cancer progression.

Marshall, A.; Roes, M.; Passos, D. T.; DeWeerd, M.; Chaikovsky, A.; Sage, J.; Howlett, C.; Dick, F. A.

10.1101/564567 — cancer biology — Posted on 2019-03-01

3271 Glycosylation of Zika Virus Is Important in Host-Virus Interaction and Pathogenesis

Routhu, N. K.; Lehoux, S. D.; Rouse, E. A.; Bidokhti, M. R. M.; Giron, L. B.; Anzurez, A.; Reid, S. P.; Abdel-Mohsen, M.; Cummings, R. D.; Byrareddy, S. N.

10.1101/564542 — biochemistry — Posted on 2019-03-01

3272 Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Gurbatri, C.; Coker, C.; Hinchliffe, T. E.; Lia, I.; Castro, S.; Treuting, P. M.; Arpaia, N.; Danino, T.

10.1101/562785 — synthetic biology — Posted on 2019-03-01

3273 mTORC1 IN THE ORBITOFRONTAL CORTEX PROMOTES HABITUAL ALCOHOL SEEKING

Morisot, N.; Berger, A.; Phamluong, K.; Laguesse, S.; Moffat, J.; Ron, D.

10.1101/564310 — neuroscience — Posted on 2019-03-01

3274 Decreasing Serine Levels During Growth Transition Triggers Biofilm Formation in Bacillus subtilis

Greenwich, J.; Reverdy, A.; Gozzi, K.; Di Cecco, G.; Tashjian, T. F.; Godoy-Carter, V.; Chai, Y.

10.1101/564526 — microbiology — Posted on 2019-03-01

3275 Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology

Mesman, A. W.; Soto, M.; Coit, J.; Calderon, R.; Aliaga, J.; Pollock, N. R.; Mendoza, M.; Mestanza, F. M.; Mendoza, C. J.; Murray, M. B.; Lecca, L.; Holmberg, R.; Franke, M. F.

10.1101/564088 — microbiology — Posted on 2019-03-01

3276 Streamlined low-input transcriptomics through EASY-RNAseq

Zhou, Y.; Xu, H.; Wu, H.; Yu, H.; Zhou, P.; Qiu, X.; Zheng, Z.; Chen, Q.; Xu, F.; Li, G.; Zhou, J.; Cheng, G.; He, W.; Zou, L.; Wan, Y.

10.1101/564468 — genomics — Posted on 2019-03-01

3277 Pluripotency and the origin of animal multicellularity

Sogabe, S.; Hatleberg, W.; Kocot, K.; Say, T.; Stoupin, D.; Roper, K.; Fernandez-Valverde, S.; Degnan, S.; Degnan, B.

10.1101/564518 — evolutionary biology — Posted on 2019-03-01

3278 Comparing Time Series Transcriptome Data Between Plants Using A Network Module Finding Algorithm

Lee, J.; Heath, L.; Grene, R.; Li, S.

10.1101/564286 — bioinformatics — Posted on 2019-03-01

3279 A molecular model for self-assembly of synaptonemal complex protein SYCE3

Dunne, O. M.; Davies, O. R.

10.1101/564237 — biochemistry — Posted on 2019-03-01

3280 Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification

Thomas, S. E.; Whitehouse, A. J.; Brown, K.; Belardinelli, J. M.; Lahiri, R.; Libardo, M. D. J.; Gupta, P.; Malhotra, S.; Boshoff, H. I. M.; Jackson, M.; Abell, C.; Coyne, A. G.; Blundell, T. L.; Floto, R. A.; Mendes, V.