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Archive, 2023-03

4 Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR
Skoufou-Papoutsaki, N.; Adler, S.; D'Santos, P.; Mannion, L.; Mehmed, S.; Kemp, R.; Smith, A.; Perrone, F.; Nayak, K.; Russell, A.; Zilbauer, M.; Winton, D. J.
10.1101/2023.03.31.535108 — cell biology — Posted on 2023-03-31
6 Rhytidome- and cork-type barks of holm oak, cork oak and their hybrids highlight processes leading to cork formation
Armendariz, I.; Lopez de Heredia, U.; Soler, M.; Puigdemont, A.; Ruiz, M. M.; Jove, P.; Soto, A.; Serra, O.; Figueras, M.
10.1101/2023.03.31.535027 — cell biology — Posted on 2023-03-31
7 PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis
Jokl, E.; Mullan, A.; Simpson, K.; Birchall, L.; Pearmain, L.; Martin, K.; Pritchett, J.; Shah, R.; Hodson, N.; Williams, C.; Camacho, E.; Zeef, L.; Donaldson, I.; Athwal, V.; Hanley, N.; Piper Hanley, K.
10.1101/2023.03.31.535067 — cell biology — Posted on 2023-03-31
9 Fatty links between multisystem proteinopathy and Small VCP-Interacting Protein
Ramzan, F.; Abrar, F.; Kumar, A.; Liao, L. M. Q.; Campbell, Z. E.; Gray, R. V.; Akanni, O.; Guyn, C. M.; Martin, D. D. O.
10.1101/2023.03.31.531359 — cell biology — Posted on 2023-03-31
11 Metabolic reprogramming provides a novel approach to overcome resistance to BH3-mimetics in Malignant Pleural Mesothelioma
Sun, X.-M.; Miles, G. J.; Craxton, A.; Powley, I. R.; Galavotti, S.; Chernova, T.; Dawson, A.; Nakas, A.; Willis, A. E.; Cain, K.; MacFarlane, M.
10.1101/2023.03.31.534530 — cell biology — Posted on 2023-03-31
12 Regulation of VEGFR2 and AKT signaling by Musashi-2 in lung cancer
Bychkov, I.; Topchu, I.; Makhov, P.; Kudinov, A.; Patel, J. D.; Boumber, Y.
10.1101/2023.03.29.534783 — cell biology — Posted on 2023-03-31
15 Few-shot learning: temporal scaling in behavioral and dopaminergic learning
Burke, D. A.; Jeong, H.; Wu, B.; Lee, S. A.; Floeder, J. R.; K Namboodiri, V. M.
10.1101/2023.03.31.535173 — neuroscience — Posted on 2023-03-31
20 Functional convergence of genomic and transcriptomic genetic architecture underlying sociability in a live-bearing fish
Corral-Lopez, A.; Bloch, N. I.; van der Bijl, W.; Cortazar-Chinarro, M.; Szorkovszky, A.; Kotrschal, A.; Darolti, I.; Buechel, S. D.; Romenskyy, M.; Kolm, N.; Mank, J. E.
10.1101/2023.02.13.528353 — evolutionary biology — Posted on 2023-03-31
21 Reproducible chemostat cultures to eliminate eukaryotic viruses from fecal transplant material
Adamberg, S.; Rasmussen, T. S.; Larsen, S. B.; Mao, X.; Nielsen, D. S.; Adamberg, K.
10.1101/2023.03.15.529189 — microbiology — Posted on 2023-03-31
22 Gut-resident microorganisms and their genes are associated with cognition and neuroanatomy in children
Bonham, K. S.; Bottino, G. F.; McCann, S. H.; Beauchemin, J.; Weisse, E.; Barry, F.; Cano-Lorente, R.; RESONANCE Consortium, ; Huttenhower, C.; Bruchhage, M. M. K.; D'Sa, V.; Deoni, S.; Klepac-Ceraj, V.
10.1101/2020.02.13.944181 — microbiology — Posted on 2023-03-31
23 Identifying keystone species in microbial communities using deep learning
Wang, X.-W.; Sun, Z.; Jia, H.; Michel-Mata, S.; Angulo, M. T.; Dai, L.; He, X.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2023.03.15.532858 — microbiology — Posted on 2023-03-31
24 Effects of combined use of alcohol and delta-9-tetrahydrocannibinol on working memory in Long Evans rats
Carrica, L. K.; Choi, C. Y.; Walter, F. A.; Noonan, B. L.; Shi, L.; Johnson, C. T.; Bradshaw, H. B.; Liang, N.-C.; Gulley, J. M.
10.1101/2023.02.02.526698 — neuroscience — Posted on 2023-03-31
27 An atlas and database of neuropeptide gene expression in the adult zebrafish forebrain
Hiraki-Kajiyama, T.; Miyasaka, N.; Ando, R.; Wakisaka, N.; Itoga, H.; Onami, S.; Yoshihara, Y.
10.1101/2023.03.29.534505 — neuroscience — Posted on 2023-03-31
29 Continuous decision to wait for a future reward is guided by fronto-hippocampal anticipatory dynamics
Shintaki, R.; Tanaka, D.; Suzuki, S.; Yoshimoto, T.; Sadato, N.; Chikazoe, J.; Jimura, K.
10.1101/2021.11.16.468916 — neuroscience — Posted on 2023-03-31
30 A web-based histology atlas for the freshwater crustacean Daphnia magna
Ngu, M. S.; Vanselow, D. X.; Zaino, C. R.; Shearer, D. A.; Harris, C.; Yakovlev, M. A.; Katz, S. R.; Lin, A. Y.; Copper, J. E.; Parkinson, D.; Beaton, M.; Colbourne, J. K.; Cheng, K. C.; Ang, K. C.
10.1101/2022.03.09.483544 — zoology — Posted on 2023-03-31
32 StereoCell enables highly accurate single-cell segmentation for spatial transcriptomics
Li, M.; Liu, H.; Li, M.; Fang, S.; Kang, Q.; Zhang, J.; Teng, F.; Wang, D.; Cen, W.; Li, Z.; Feng, N.; Guo, J.; He, Q.; Wang, L.; Zheng, T.; Li, S.; Bai, Y.; Xie, M.; Bai, Y.; Liao, S.; Chen, A.; Brix, S.; Xu, X.; Zhang, Y.; Li, Y.
10.1101/2023.02.28.530414 — bioinformatics — Posted on 2023-03-31
37 From southern Africa and beyond: historical biogeography of a monocotyledonous bulbous geophyte
Howard, C. C.; Nanyeni, L.; Mollel, N.; Chuba, D.; Zuntini, A. R.; Malakasi, P.; Harvey, T. S.; Cellinese, N.
10.1101/2022.09.21.508857 — evolutionary biology — Posted on 2023-03-31
39 Brain age predictions in longitudinal data reveal the importance of scan quality and field strength
Korbmacher, M.; Wang, M.-Y.; Eikeland, R.; Buchert, R.; Leonardsen, E.; Westlye, L. T.; Maximov, I. I.; Specht, K.
10.1101/2023.03.31.535038 — neuroscience — Posted on 2023-03-31
40 Circuit-specific selective vulnerability in the DMN persists in the face of widespread amyloid burden.
Brunwasser, S. J.; Farris, C.; Elmore, H.; Dyer, E. L.; Nair, K. B.; Whitesell, J. D.; Harris, J. A.; Hengen, K. B.
10.1101/2022.11.14.516510 — neuroscience — Posted on 2023-03-31
41 Growth/differentiation factor 15 controls number of ependymal and neural stem cells in the ventricular-subventricular zone
Baur, K.; Carrillo Garcia, C.; San, S.; von Hahn, M.; Strelau, J.; Hölzl-Wenig, G.; Mandl, C.; Ciccolini, F.
10.1101/2022.12.02.518869 — neuroscience — Posted on 2023-03-31
42 Nuclear morphology predicts cell survival to cisplatin chemotherapy
Kim, C.-J.; Gonye, A. L.; Truskowski, K.; Lee, C.-F.; Austin, R.; Pienta, K. J.; Amend, S. R.
10.1101/2022.09.19.508515 — cancer biology — Posted on 2023-03-31
44 Epigenetic mechanisms to propagate histone acetylation by p300/CBP
Kikuchi, M.; Morita, S.; Wakamori, M.; Sato, S.; Uchikubo-Kamo, T.; Shirouzu, M.; Umehara, T.
10.1101/2023.03.31.535039 — biochemistry — Posted on 2023-03-31
47 Nucleoporin Nsp1 surveils the phase state of FG-Nups
Otto, T. A.; Bergsma, T.; Dekker, M.; Mouton, S.; Gallardo, P.; Wolters, J. C.; Steen, A.; Onck, P. R.; Veenhoff, L. L.
10.1101/2023.03.31.535084 — cell biology — Posted on 2023-03-31
50 RIF1 regulates replication origin activity and early replication timing in B cells
Malzl, D.; Peycheva, M.; Rahjouei, A.; Gnan, S.; Klein, K.; Nazarova, M.; Schoeberl, U. E.; Gilbert, D. M.; Buonomo, S.; Di Virgilio, M.; Neumann, T.; Pavri, R.
10.1101/2023.03.31.535086 — molecular biology — Posted on 2023-03-31
51 Identification of culturable fungi and bacteria in mosquito saliva and impact on arbovirus infection in vitro
Wang, L.; Remue, L.; Verwimp, S.; Adriaens, N.; Rivas, F.; Soto, A.; van Bree, J.; Garigliany, M.; Delang, L.
10.1101/2023.03.31.534949 — microbiology — Posted on 2023-03-31
52 Early microbial intervention reduces diarrhea while improves later milk production in newborn calves
Shen, Y.; Li, Y.; Wu, T.; Dong, Q.; Deng, Q.; Liu, L.; Guo, Y.; Cao, Y.; Li, Q.; Shi, J.; Zou, H.; Jiao, Y.; Ding, L.; Li, J.; Gao, Y.; Hu, S.; Wang, Y.; Chen, L.
10.1101/2023.03.30.535013 — microbiology — Posted on 2023-03-31
55 Targeted genomic sequencing of avian influenza viruses in wetlands sediment from wild bird habitats
Kuchinski, K.; Coombe, M.; Mansour, S. C.; Cortez, G. A. P.; Kalhor, M.; Himsworth, C. G.; Prystajecky, N. A.
10.1101/2023.03.30.534984 — genomics — Posted on 2023-03-31
57 TopBP1 utilises a bipartite GINS binding mode to activate the replicative helicase
Boos, D.; Day, M.; Tetik, B.; Parlak, M.; Almeida-Hernandez, Y.; Raeschle, M.; Kaschani, F.; Siegert, H.; Marko, A.; Sanchez-Garcia, E.; Kaiser, M.; Barker, I.; Pearl, L. H.; Oliver, A.
10.1101/2023.03.31.535063 — molecular biology — Posted on 2023-03-31
61 Real-time PCR detection of mixed Plasmodium ovale curtisi and wallikeri species infections in human and mosquito hosts
Potlapalli, V.; Muller, M. S.; Ngasala, B.; Ali, I. M.; Na, Y. B.; Williams, D. R.; Kharabora, O.; Chhetri, S.; Lu, M. S.; Carey-Ewend, K.; Lin, F.-C.; Mathias, D.; Tarimo, B. B.; Juliano, J. J.; Parr, J.; Lin, J. T.
10.1101/2023.03.31.535020 — microbiology — Posted on 2023-03-31
63 Temporal colonization of the gut microbiome in neonatal Bos taurus at single nucleotide resolution
Dong, Q.; Hua, D.; Wang, X.; Jiao, Y.; Liu, L.; Deng, Q.; Wu, T.; Zou, H.; Ding, L.; Hu, S.; Shi, J.; Wang, Y.; Sheng, Y.; Sun, W.; Shen, Y.; Tang, L.; Kong, X.; Chen, L.
10.1101/2023.03.30.535011 — microbiology — Posted on 2023-03-31
64 Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis
Spaas, J.; Van der Stede, T.; de Jager, S.; van de Waterweg Berends, A.; Tiane, A.; Baelde, H.; Baba, S. P.; Eckhardt, M.; Wolfs, E.; Vanmierlo, T.; Hellings, N.; Eijnde, B. O.; Derave, W.
10.1101/2023.03.30.534899 — neuroscience — Posted on 2023-03-31
68 Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by Atf4 following optic nerve injury
Somasundaram, P.; Farley, M. M.; Rudy, M. A.; Stefanoff, D. G.; Shah, M.; Goli, P.; Heo, J.; Wang, S.; Tran, N. M.; Watkins, T. A.
10.1101/2023.03.29.534798 — neuroscience — Posted on 2023-03-31
69 Angular head velocity cells within brainstem nuclei projecting to the head direction circuit
Graham, J. A.; Dumont, J. R.; Winter, S. S.; Brown, J. E.; LaChance, P. A.; Amon, C. C.; Farnes, K. B.; Morris, A. J.; Streltzov, N. A.; Taube, J. S.
10.1101/2023.03.29.534808 — animal behavior and cognition — Posted on 2023-03-31
72 Neural and behavioral signatures of the multidimensionality of manipulable object processing.
Almeida, J.; Fracasso, A.; Kristensen, S.; Valerio, D.; Bergström, F.; Chakravarthi, R.; Tal, Z.; Walbrin, J.
10.1101/2023.03.29.534804 — neuroscience — Posted on 2023-03-31
73 Spectrally and temporally resolved estimation of neural signal diversity
Mediano, P. A. M.; Rosas, F. E.; Luppi, A. I.; Noreika, V.; Seth, A. K.; Carhart-Harris, R. L.; Barnett, L.; Bor, D.
10.1101/2023.03.30.534922 — neuroscience — Posted on 2023-03-31
75 Activity-dependent constraints on catecholamine signaling
Li, L.; Rana, A. N.; Li, E. M.; Feng, J.; Li, Y.; Bruchas, M.
10.1101/2023.03.30.534970 — neuroscience — Posted on 2023-03-31
79 Handedness and its association with education and spatial navigation assessed in over 400,000 participants across 41 countries
Fernandez-Velasco, P.; Coutrot, A.; Oloye, H.; Wiener, J. M.; Dalton, R. C.; Hoelscher, C.; Manley, E.; Hornberger, M.; Spiers, H.
10.1101/2023.03.30.534904 — animal behavior and cognition — Posted on 2023-03-31
80 Assessing bias and robustness of social network metrics using GPS based radio-telemetry data
Kaur, P.; Ciuti, S.; Ossi, F.; Cagnacci, F.; Morellet, N.; Loison, A.; Atmeh, K.; McLoughlin, P.; Reinking, A. K.; Beck, J. L.; Ortega, A. C.; Kauffman, M.; Boyce, M. S.; Salter-Townshend, M.
10.1101/2023.03.30.534779 — animal behavior and cognition — Posted on 2023-03-31
84 Enhanced selectivity of transcutaneous spinal cord stimulation by multielectrode configuration
Bryson, N. K.; Lombardi, L.; Hawthorn, R.; Fei, J.; Keesey, R.; Peiffer, J. D.; Seanez, I.
10.1101/2023.03.30.534835 — neuroscience — Posted on 2023-03-31
85 pan-ECM: live brain extracellular matrix imaging with protein-reactive dye
Ge, X.; Xu, X.; Cai, Q.; Xiong, h.; Chen, X.; Hong, Y.; Gao, X.; Yao, Y.; Bachoo, R.; Qin, Z.
10.1101/2023.03.29.534827 — neuroscience — Posted on 2023-03-31
86 Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia
Ruiz-Rizzo, A. L.; Finke, K.; Damoiseaux, J. S.; Bartels, C.; Buerger, K.; Cosma, N. C.; Dechent, P.; Dobisch, L.; Ewers, M.; Fliessbach, K.; Frommann, I.; Glanz, W.; Goerss, D.; Hetzer, S.; Incesoy, E. I.; Janowitz, D.; Kilimann, I.; Laske, C.; Melo van Lent, D.; Munk, M. H. J.; Peters, O.; Priller, J.; Ramirez, A.; Rostamzadeh, A.; Roy, N.; Scheffler, K.; Schneider, A.; Spottke, A.; Spruth, E. J.; Teipel, S.; Wagner, M.; Wiltfang, J.; Yakupov, R.; Jessen, F.; Duezel, E.; Perneczky, R.; Rauchmann, B.-S.
10.1101/2023.03.31.534758 — neuroscience — Posted on 2023-03-31
90 Cryo-EM Structures of Amyloid-β Fibrils from Alzheimer's Disease Mouse Models
Zielinski, M.; Reyes, F. S. P.; Gremer, L.; Schemmert, S.; Frieg, B.; Willuweit, A.; Donner, L.; Elvers, M.; Nilsson, L. N. G.; Syvänen, S.; Sehlin, D.; Ingelsson, M.; Willbold, D.; Schröder, G. F.
10.1101/2023.03.30.534981 — neuroscience — Posted on 2023-03-31
92 Parvalbumin-expressing basal forebrain neurons mediate learning from negative experience
Hegedus, P.; Lyakhova, V.; Velencei, A.; Mayer, M. I.; Zelenak, Z.; Nyiri, G.; Hangya, B.
10.1101/2023.03.31.535018 — neuroscience — Posted on 2023-03-31
96 Evaluation of surface-based hippocampal registration using ground-truth subfield definitions
DeKraker, J.; Palomero-Gallagher, N.; Kedo, O.; Ladbon-Bernasconi, N.; Muenzing, S. E. A.; Axer, M.; Amunts, K.; Khan, A. R.; Bernhardt, B.; Evans, A. C.
10.1101/2023.03.30.534978 — neuroscience — Posted on 2023-03-31
102 Mechanistic investigation of SARS-CoV-2 Omicron variant spike mutants via full quantum mechanical modeling
Zaccaria, M.; Genovese, L.; Lawhorn, B.; Dawson, W.; Joyal, A. S.; Hu, J.; Autissier, P.; Nakajima, T.; Johnson, W. E.; Fofana, I.; Farzan, M.; Momeni, B.
10.1101/2021.12.01.470748 — biophysics — Posted on 2023-03-31
103 miRNA binding pressure channels evolution of SARS-CoV-2 genomes
Zhiyanov, A.; Shkurnikov, M.; Nersisyan, A.; Cai, H.; Baranova, A.; Tonevitsky, A.
10.1101/2023.03.31.535057 — evolutionary biology — Posted on 2023-03-31
104 Determinants of species-specific utilization of ACE2 by human and animal coronaviruses
Wang, Q.; Noettger, S.; Xie, Q.; Pastorio, C.; Seidel, A.; Mueller, J. A.; Jung, C.; Jacob, T.; Sparrer, K. M. J.; Zech, F.; Kirchhoff, F.
10.1101/2023.03.31.535059 — molecular biology — Posted on 2023-03-31
105 S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness
Yurkovetskiy, L.; Egri, S.; Kurhade, C.; Diaz-Salinas, M. A.; Jaimes, J. A.; Nyalile, T.; Xie, X.; Choudhary, M. C.; Dauphin, A.; Li, J. Z.; Munro, J. B.; Shi, P.-Y.; Shen, K.; Luban, J.
10.1101/2023.03.30.535005 — microbiology — Posted on 2023-03-31
107 Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia
Castaneda, D. C.; Jangra, S.; Yurieva, M.; Martinek, J.; Callender, M.; Coxe, M.; Choi, A.; Diego, J. G.-B.; Lin, J.; Wu, T.-C.; Marches, F.; Chaussabel, D.; Yu, P.; Salner, A.; Aucello, G.; Koff, J.; Hudson, B.; Church, S. E.; Gorman, K.; Anguiano, E.; Garcia-Sastre, A.; Williams, A.; Schotsaert, M.; Palucka, K.
10.1101/2023.03.30.534980 — immunology — Posted on 2023-03-31
112 TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron
Kim, T. W.; Koo, S. Y.; Riessland, M.; Cho, H.; Chaudhry, F.; Kolisnyk, B.; Russo, M. V.; Saurat, N.; Mehta, S.; Garippa, R.; Betel, D.; Studer, L.
10.1101/2023.03.29.534819 — neuroscience — Posted on 2023-03-31
115 Single particle profiler for measuring content and properties of nano-sized bioparticles
Sych, T.; Schlegel, J.; Barriga, H.; Ojansivu, M.; Hanke, L.; Weber, F.; Bostancioglu, B.; Ezzat, K.; Stangl, H.; Plochberger, B.; Laurencikiene, J.; El Andaloussi, S.; Furth, D.; Stevens, M.; Sezgin, E.
10.1101/2022.07.08.499323 — biophysics — Posted on 2023-03-31
117 Novel insights into the cold resistance of Hevea brasiliensis through coexpression networks
Silva, C. C.; Bajay, S. K.; Aono, A. H.; Francisco, F. R.; Junior, R. B.; de Souza, A. P.; Mantello, C. C.; Vicentini dos Santos, R.
10.1101/2021.11.02.466997 — genomics — Posted on 2023-03-31
121 Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
Boyle, K. A.; Polgar, E.; Gutierrez-Mecinas, M.; Dickie, A. C.; Cooper, A. H.; Bell, A. M.; Jumolea, E.; Casas-Benito, A.; Watanabe, M.; Hughes, D. I.; Weir, G.; Riddell, J.; Todd, A. J.
10.1101/2023.02.10.528013 — neuroscience — Posted on 2023-03-31
122 Is shape in the eye of the beholder? Assessing landmarking error in geometric morphometric analyses on live fish
Moccetti, P.; Rodger, J. R.; Bolland, J. D.; Kaiser-Wilks, P.; Smith, R.; Nunn, A. D.; Adams, C. E.; Bright, J. A.; Honkanen, H. M.; Lothian, A. J.; Newton, M.; Joyce, D. A.
10.1101/2022.10.11.509915 — zoology — Posted on 2023-03-31
124 Induction of mitophagy reverts age-associated decline of the hematopoietic and immune systems
Chiang, Y.-H.; Charmoy, M.; Ginefra, P.; Schyrr, F.; Franco, F.; Ho, P.-C.; Naveiras, O.; Auwerx, J.; Held, W.; Vannini, N.
10.1101/2023.03.30.534925 — immunology — Posted on 2023-03-31
126 Single cell RNA sequencing in isogenic FUS and TARDBP mutant ALS lines reveals early mitochondrial dysfunction as a common pathway in motor neurons
Schweingruber, C.; Nijssen, J.; Mechtersheimer, J.; Reber, S.; Keuper, M.; Mei, I.; Aguila Benitez, J.; O'Brien, N.; Jastroch, M.; Ruepp, M.-D.; Hedlund, E.
10.1101/2023.03.16.531876 — neuroscience — Posted on 2023-03-31
132 High-Dimensional Spectral Cytometry Reveals Therapeutically Relevant Immune Subtypes in Gastric Cancer
Abate, M.; Fei, T.; Lin, Y.-H.; Shimada, S.; Drebin, H.; Chen, E.; Tang, L.; Strong, V. E.; Vardhana, S. A.
10.1101/2023.03.29.534765 — cancer biology — Posted on 2023-03-31
134 Comammox and Unknown Candidate AOBs Contribute to Nitrite Accumulation in An Integrated A-B stage process that Incorporates Side-stream EBPR (S2EBPR)
Yan, Y.; Lee, J.; Han, I.; Wang, Z.; McCullough, K.; Klaus, S.; Kang, D.; Wang, D.; Patel, A.; Li, G.; McQuarrie, J.; Stinson, B. M.; deBarbadillo, C.; Dombrowski, P.; Bott, C.; Gu, A. Z.
10.1101/2023.03.29.534650 — bioengineering — Posted on 2023-03-31
136 An atlas and database of neuropeptide gene expression in the adult zebrafish forebrain
Hiraki-Kajiyama, T.; Miyasaka, N.; Ando, R.; Wakisaka, N.; Itoga, H.; Onami, S.; Yoshihara, Y.
10.1101/2023.03.29.534505 — neuroscience — Posted on 2023-03-31
138 Affinity-ranking BIN1 interactions underpinning centronuclear myopathy
Zambo, B.; Edelweiss, E.; Morlet, B.; Negroni, L.; Ostergaard, S.; Trave, G.; Laporte, J.; Gogl, G.
10.1101/2023.02.14.528471 — biochemistry — Posted on 2023-03-31
142 Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple epitopes
Hurtado, J.; Rogers, T. F.; Jaffe, D. B.; Adams, B.; Bangaru, S.; Garcia, E.; Capozzola, T.; Messmer, T.; Sharma, P.; Song, G.; Beutler, N.; He, W.; Dueker, K.; Musharrafieh, R.; Stubbington, M. J. T.; Burton, D.; Andrabi, R.; Ward, A.; McDonnell, W. J.; Briney, B.
10.1101/2023.03.28.534602 — immunology — Posted on 2023-03-31
144 Why the brown ghost chirps at night
Oboti, L.; Pedraja, F.; Ritter, M.; Lohse, M.; Klette, L.; Krahe, R.
10.1101/2022.12.29.522225 — animal behavior and cognition — Posted on 2023-03-31
148 Soil depth governs microbial community assembly and enzymatic activity in extreme environments
Jing, X.; Classen, A. T.; Li, D.; Lin, L.; Lu, M.; Sanders, N. J.; Wang, Y.; Feng, W.
10.1101/2022.08.17.504275 — ecology — Posted on 2023-03-31
149 Conformational change in the monomeric alpha-synuclein imparts fibril polymorphs
Aguirre, C.; Ikenaka, K.; So, M.; Maruno, T.; Yamaguchi, K.; Nakajima, K.; Choong, C.-J.; Nabekura, K.; Beck, G.; TOMII, K.; Yamamori, Y.; Doi, J.; Matsubara, T.; Morishima, M.; Kakuda, K.; Hideshim, M.; Wang, N.; Ajiki, T.; Mohamed Mohamed Badawy, S.; Kimura, Y.; Nagano, S.; Baba, K.; Murayama, S.; Ogi, H.; Nagai, Y.; Kawata, Y.; Uchiyama, S.; Miyanoiri, Y.; Goto, Y.; Mochizuki, H.
10.1101/2022.02.10.479831 — biophysics — Posted on 2023-03-31
150 The C9Orf72 hexanucleotide repeat expansion aggregates by means of multimolecular G-quadruplex formation.
Raguseo, F.; Tanase, D.; Maher, T. E.; Malouf, L.; Rubio Sanchez, R.; Elani, Y.; Di Michele, L.; Di Antonio, M.
10.1101/2023.01.31.526399 — biochemistry — Posted on 2023-03-31
152 Genetic and neural bases of the Neuroticism general factor
Lee, J. J.; Kim, Y.; Giannelis, A.; Willoughby, E. A.; DeYoung, C. G.
10.1101/2023.03.08.531776 — genetics — Posted on 2023-03-30
153 AutophagyNet: High-resolution data source for the analysis of autophagy and its regulation
Csabai, L.; Bohar, B.; Turei, D.; Prabhu, S.; Foldvari-Nagy, L.; Madgwick, M.; Fazekas, D.; Modos, D.; Olbei, M.; Halka, T.; Poletti, M.; Kornilova, P.; Kadlecsik, T.; Demeter, A.; Szalay-Beko, M.; Kapuy, O.; Lenti, K.; Vellai, T.; Gul, L.; Korcsmaros, T.
10.1101/2023.03.30.534858 — bioinformatics — Posted on 2023-03-30
154 Integrated spatiotemporal transcriptomic resolution of embryonic palate osteogenesis
Oliver Pina, J.; Raju, R.; Roth, D. M.; Chattaraj, P.; Kidwai, F. K.; Faucz, F. R.; Iben, J. R.; Mitra, A.; Campbell, K.; Fridell, G.; Esnault, C.; Dale, R. K.; D'Souza, R. N.
10.1101/2023.03.30.534875 — developmental biology — Posted on 2023-03-30
155 Atypical beta-band effects in children with dyslexia in response to rhythmic audio-visual speech
Keshavarzi, M.; Mandke, K.; Macfarlane, A.; Parvez, L.; Gabrielczyk, F.; Wilson, A.; Goswami, U.
10.1101/2023.03.29.534542 — neuroscience — Posted on 2023-03-30
160 Medial Prefrontal Cortex Serotonin Input Regulates Cognitive Flexibility in Mice
Morgan, A. A.; Alves, N. D.; Stevens, G. S.; Yeasmin, T.; Mackay, A.; Power, S. K.; Sargin, D.; Hanna, C.; Adib, A.; Ziolkowski-Blake, A.; Lambe, E. K.; Ansorge, M. S.
10.1101/2023.03.30.534775 — neuroscience — Posted on 2023-03-30
164 Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats
Janganati, V.; Salazar, P.; Parks, B. J.; Gorman, G. S.; Prather, P. L.; Peterson, E. C.; Alund, A. W.; Moran, J. H.; Crooks, P. A.; Brents, L. K.
10.1101/2022.12.12.520120 — pharmacology and toxicology — Posted on 2023-03-30
165 High-level production of nervonic acid in the oleaginous yeast Yarrowia lipolytica by systematic metabolic engineering
Su, H.; Shi, P.; Shen, Z.; Meng, H.; Meng, Z.; Han, X.; chen, Y.; Fan, W.; Fa, Y.; Yang, C.; Li, F.; Wang, S.
10.1101/2023.03.28.534371 — bioengineering — Posted on 2023-03-30
168 HDAC11 inhibition triggers bimodal thermogenic pathways to circumvent adipocyte catecholamine resistance
Robinson, E. L.; Bagchi, R. A.; Major, J. L.; Bergman, B. C.; Madsuda, J. L.; McKinsey, T. A.
10.1101/2023.03.29.534830 — molecular biology — Posted on 2023-03-30
169 Specificity and mechanism of 1,6 hexanediol-induced disruption of nuclear transport
Riquelme Barrientos, E.; Otto, T. A.; Mouton, S. N.; Steen, A.; Veenhoff, L. M.
10.1101/2023.03.30.534880 — molecular biology — Posted on 2023-03-30
171 DYRK1A interacts with Tuberous Sclerosis complex and promotes mTORC1 activity
Wang, P.; Sarkar, S.; Zhang, M.; Zhang, Z.; Datta, S.; Jayaram, N.; Datta, S.; He, R.; Wu, P.; Chao, P.; Zhang, Y.; Washburn, M. P.; Florens, L.; Nagarkar-Jaiswal, S.; Jaiswal, M.; Mohan, M.
10.1101/2023.01.18.524493 — molecular biology — Posted on 2023-03-30
172 Microbiome diversity: A barrier to the environmental spread of antimicrobial resistance?
Klümper, U.; Gionchetta, G.; Catao, E. C.; Bellanger, X.; Dielacher, I.; Fang, P.; Galazka, S.; Goryluk-Salmonowicz, A.; Kneis, D.; Okoroafor, U.; Radu, L.-E.; Szadziul, M.; Szekeres, E.; Teban-Man, A.; Coman, C.; Kreuzinger, N.; Popowska, M.; Vierheilig, J.; Walsh, F.; Woegerbauer, M.; Bürgmann, H.; Merlin, C.; Berendonk, T. U.
10.1101/2023.03.30.534382 — microbiology — Posted on 2023-03-30
173 Prevalence of Slam-dependent hemophores in Gram-negative bacteria
Moraes, T. F.; Shin, H. E.; Pan, C.; Curran, D. M.; Bateman, T. J.; Chong, D. H.; Ng, D.; Shah, M.
10.1101/2023.03.29.534853 — microbiology — Posted on 2023-03-30
174 Peripheral detection of viruses shapes brain immunity and behavior in zebrafish
Kraus, A.; Garcia, B.; Ma, J.; Herrera, K. J.; Zwaka, H.; Harpaz, R.; Wong, R.; Engert, F.; Salinas, I.
10.1101/2023.03.17.533129 — immunology — Posted on 2023-03-30
179 Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome: mechanism of action and therapeutic potential
Stewart, T. R. M.; Foley, J. R.; Holbert, C. E.; Khomutov, M. A.; Rastkari, N.; Tao, X.; Khomutov, A. R.; Zhai, R. G.; Casero, R. A.
10.1101/2023.03.30.534977 — biochemistry — Posted on 2023-03-30
180 In Campylobacter jejuni a new type of chaperone receives heme b from ferrochelatase
Zamarreno Beas, J.; Videira, M. A.; Karavaeva, V.; Lourenco, F. S.; Almeida, M. R.; Sousa, F.; Saraiva, L. M.
10.1101/2023.03.30.534706 — biochemistry — Posted on 2023-03-30
183 Micropolarity governs the structural organization of biomolecular condensates
Ye, S.; Latham, A.; Tang, Y.; Hsiung, C.-H.; Chen, J.; Luo, F.; Liu, Y.; Zhang, B.; Zhang, X.
10.1101/2023.03.30.534881 — biochemistry — Posted on 2023-03-30
185 Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer
Hosseini, A.; Lindholm, H. T.; Chen, R.; Mehdipour, P.; Marhon, S. A.; Ishak, C. A.; De Carvalho, D. D.
10.1101/2023.03.30.531699 — cell biology — Posted on 2023-03-30
186 Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis.
Ng, J. Q.; Jafarov, T. H.; Little, C. B.; Wang, T.; Ali, A.; Ma, Y.; Radford, G.; Vrbanac, L.; Ichinose, M.; Whittle, S.; Hunter, D.; Lannagan, T.; Suzuki, N.; Goyne, J. M.; Kobayashi, H.; WANG, T. C.; Haynes, D.; Menicanin, D.; Gronthos, S.; Worthley, D. L.; Woods, S. L.; Mukherjee, S.
10.1101/2023.03.29.534651 — cell biology — Posted on 2023-03-30
188 Wide distribution of Mediterranean and African Spotted fever agents and the first identification of Israeli Spotted Fever agent in ticks in Uganda
Eneku, W.; Erima, B.; Byaruhanga, A. M.; Atim, G.; Tugume, T.; Ukuli, Q. A.; Kibuuka, H.; Mworozi, E.; Burrows, C.; Koehler, J. W.; Cleary, N. G.; von Fricken, M. E.; Tweyongyere, R.; Wabwire-Mangen, F.; Byarugaba, D. K.
10.1101/2023.03.29.534855 — molecular biology — Posted on 2023-03-30
189 Bacterial defences interact synergistically by disrupting phage cooperation
Maestri, A.; Pursey, E.; Chong, C.; Pons, B. J.; Gandon, S.; Custodio, R.; Chisnall, M.; Grasso, A.; Paterson, S.; Baker, K. S.; van Houte, S.; Chevallereau, A.; Westra, E.
10.1101/2023.03.30.534895 — microbiology — Posted on 2023-03-30
194 Comparative genomics of carbapenemase-producing Morganella spp.
Bonnin, R. A.; Creton, E.; PERRIN, A.; Girlich, D.; Emeraud, C.; Jousset, A. B.; Duque, M.; Hopkins, K.; Bogaerts, P.; Glupczynski, Y.; Gniadkowski, M.; Hendrickx, A. P. A.; Van Der Zwaluw, K.; Apfalter, P.; Hartl, R.; Heringova, V.; Hrabak, J.; Larrouy-Maumus, G.; Rocha, E.; Naas, T.; Dortet, L.
10.1101/2023.03.30.534920 — microbiology — Posted on 2023-03-30
197 Ketolysis is Required for the Proper Development and Function of the Somatosensory Nervous System.
Enders, J.; Jack, J.; Thomas, S.; Lynch, P.; Lasnier, S.; Cao, X.; Swanson, M. T.; Ryals, J. M.; Thyfault, J. P.; Puchalska, P.; Crawford, P. A.; Wright, D. E.
10.1101/2023.01.11.523492 — neuroscience — Posted on 2023-03-30
199 An easy-to-use microfluidic mechano-chemostat for tissues and organisms reveals that confined growth is accompanied with increased macromolecular crowding
Ben Meriem, Z.; Mateo, T.; Faccini, J.; Denais, C.; Dufour-Castan, R.; Guynet, C.; Merle, T.; Suzanne, M.; Di-Luoffo, M.; Guillermet-Guibert, J.; Alric, B.; Landiech, S.; Malaquin, L.; Mesnilgrente, F.; Laborde, A.; Mazenq, L.; Courson, R.; Delarue, M.
10.1101/2023.03.29.534752 — biophysics — Posted on 2023-03-30
201 Cancer-keeping genes as therapeutic targets
Zhang, X.; Pan, C.; Wei, X.; Yu, M.; Liu, S.; An, J.; Yang, J.; Wei, B.; Hao, W.; Yao, Y.; Zhu, Y.; Zhang, W.
10.1101/2022.06.13.495906 — bioinformatics — Posted on 2023-03-30
203 Large-scale Annotation of Biochemically Relevant Pockets and Tunnels in Cognate Enzyme-Ligand Complexes
Vavra, O.; Tyzack, J.; Haddadi, F.; Stourac, J.; Damborsky, J.; Mazurenko, S.; Thornton, J.; Bednar, D.
10.1101/2023.03.29.534735 — bioinformatics — Posted on 2023-03-30
205 High-Throughput Bioprinting of the Nasal Epithelium using Patient-derived Nasal Epithelial Cells
Derman, I. D.; Yeo, M.; Castaneda, D. C.; Callender, M.; Horvath, M.; Mo, Z.; Xiong, R.; Fleming, E.; Chen, P.; Peeples, M. E.; Palucka, K.; Oh, J.; Ozbolat, I. T.
10.1101/2023.03.29.534723 — bioengineering — Posted on 2023-03-30
207 Deficiency of ZC3HC1 modulates vascular smooth muscle cell phenotype and increases neointima formation
Aherrahrou, R.; Reinberger, T.; Werner, J.; Otto, M.; Al-Hasani, J.; Munoz-Venegas, L.; Yin, X.; Mayr, M.; Civelek, M.; Schunkert, H.; Kessler, T.; Erdmann, J.; Aherrahrou, Z.
10.1101/2021.09.29.462212 — genetics — Posted on 2023-03-30
209 Coexistence of many species under a random competition-colonization trade-off
Miller, Z. R.; Clenet, M.; Della Libera, K.; Massol, F.; Allesina, S.
10.1101/2023.03.23.533867 — ecology — Posted on 2023-03-30
211 The bromodomain inhibitor JQ1 is a molecular glue targeting centromeres
Corless, S.; Singh, N. P.; Benabdallah, N.; Boehm, J.; Simon, A. M.; Dolejs, V.; Anders, S.; Banito, A.; Erhardt, S.
10.1101/2023.03.15.532673 — molecular biology — Posted on 2023-03-30
216 Functional connectomics reveals general wiring rule in mouse visual cortex
Ding, Z.; Fahey, P. G.; Papadopoulos, S.; Wang, E. Y.; Celii, B.; Papadopoulos, C.; Kunin, A.; Chang, A.; Fu, J.; Ding, Z.; Patel, S.; Ponder, K.; Muhammad, T.; Bae, J. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Cobos, E.; Dorkenwald, S.; Elabbady, L.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Schneider-Mizell, C. M.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yin, W.; Yu, S.-c.; Frou
10.1101/2023.03.13.531369 — neuroscience — Posted on 2023-03-30
217 An open-access dataset of naturalistic viewing using simultaneous EEG-fMRI
Telesford, Q. K.; Gonzalez-Moreira, E.; Xu, T.; Tian, Y.; Colcombe, S. J.; Cloud, J.; Russ, B. E.; Falchier, A.; Nentwich, M.; Madsen, J.; Parra, L. C.; Schroeder, C.; Milham, M.; Franco, A. R.
10.1101/2022.11.23.517540 — neuroscience — Posted on 2023-03-30
218 Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance
Bernstock, J. D.; Willis, C. M.; Garcia-Segura, M. E.; Gaude, E.; Anni, D.; Lee, Y.-j.; Thomas, L. W.; Casey, A.; Vicario, N.; Leonardi, T.; Nicaise, A. M.; Gessler, F. A.; Izzy, S.; Buffelli, M. R.; Seidlitz, J.; Srinivasan, S.; Murphy, M. P.; Ashcroft, M.; Cambiaghi, M.; Hallenbeck, J. M.; Peruzzotti-Jametti, L.
10.1101/2023.03.29.534718 — neuroscience — Posted on 2023-03-30
219 Cross-validation for the estimation of effect size generalizability in mass-univariate brain-wide association studies
Goltermann, J.; Winter, N. R.; Gruber, M.; Fisch, L.; Richter, M.; Grotegerd, D.; Dohm, K.; Meinert, S.; Leehr, E. J.; Böhnlein, J.; Kraus, A.; Thiel, K.; Winter, A.; Flinkenflügel, K.; Leenings, R.; Barkhau, C.; Ernsting, J.; Berger, K.; Minnerup, H.; Straube, B.; Alexander, N.; Jamalabadi, H.; Stein, F.; Brosch, K.; Wroblewski, A.; Thomas-Odenthal, F.; Usemann, P.; Teuteberg, L.; Pfarr, J.; Jansen, A.; Nenadic, I.; Kircher, T.; Gaser, C.; Opel, N.; Hahn, T.; Dannlowski, U.
10.1101/2023.03.29.534696 — neuroscience — Posted on 2023-03-30
222 Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9
Gerard, L.; Fourrez, M.; Salazar, P.; Sprimont, L.; Xia, D.; Ambudkar, S. V.; Gottesman, M. M.; Gillet, J.-P.
10.1101/2022.10.21.513191 — biochemistry — Posted on 2023-03-30
225 Reconstructing prehistoric viral genomes from Neanderthal sequencing data
Ferreira, R. C.; Alves, G. V.; Ramon, M.; Antoneli, F. M.; Briones, M. R.
10.1101/2023.03.16.532919 — genomics — Posted on 2023-03-30
226 Imputation of 3D genome structure by genetic-epigenetic interaction modeling in mice
Kuffler, L.; Fortin, H. J.; Skelly, D. A.; Czechanski, A.; Munger, S. C.; Reinholdt, L. G.; Baker, C. L.; Carter, G. W.
10.1101/2022.02.07.479436 — genetics — Posted on 2023-03-30
228 Assessing risk for butterflies in the context of climate change, demographic uncertainty, and heterogenous data sources
Forister, M. L.; Grames, E. M.; Halsch, C. A.; Burls, K. J.; Carroll, C. F.; Bell, K. L.; Jahner, J. P.; Bradford, T.; Zhang, J.; Cong, Q.; Grishin, N. V.; Glassberg, J.; Shapiro, A. M.; Riecke, T. V.
10.1101/2022.05.22.492972 — ecology — Posted on 2023-03-30
229 The Translation Initiation Factor Homolog, eif4e1c, Regulates Cardiomyocyte Metabolism and Proliferation During Heart Regeneration
Rao, A.; Lyu, B.; Jahan, I.; Lubertozzi, A.; Zhou, G.; Tedeschi, F.; Jankowsky, E.; Carstens, B. C.; Kang, J.; Poss, K. D.; Baskin, K.; Goldman, J. A.
10.1101/2022.08.15.502524 — developmental biology — Posted on 2023-03-30
234 Sequencing accuracy and systematic errors in nanopore direct RNA sequencing
Wang, L.; van der Toorn, W.; Bohn, P.; Hölzer, M.; Smyth, R.; von Kleist, M.
10.1101/2023.03.29.534691 — bioinformatics — Posted on 2023-03-30
235 OCT5k: A dataset of multi-disease and multi-graded annotations for retinal layers
Arikan, M.; Willoughby, J.; Ongun, S.; Sallo, F.; Montesel, A.; Ahmed, H.; Hagag, A.; Book, M.; Faatz, H.; Cicinelli, M. V.; Fawzi, A. A.; Podkowinski, D.; Cilkova, M.; de Almeida, D.; Zouache, M.; Ramsamy, G.; Lilaonitkul, W.; Dubis, A. M.
10.1101/2023.03.29.534704 — bioengineering — Posted on 2023-03-30
237 Somatic chromosome pairing has a determinant impact on 3D 1 chromatin organization
Puerto, M.; Shukla, M.; Bujosa, P.; Perez-Roldan, J.; Tamirisa, S.; Sole, C.; de Nadal, E.; Posas, F.; Azorin, F.; Rowley, J.
10.1101/2023.03.29.534693 — genomics — Posted on 2023-03-30
238 Splicing accuracy varies across human introns, tissues and age
Garcia-Ruiz, S.; Zhang, D.; Gustavsson, E. K.; Rocamora-Perez, G.; Grant-Peters, M.; Fairbrother-Browne, A.; Reynolds, R. H.; Brenton, J. W.; Gil-Martinez, A. L.; Chen, Z.; Rio, D. C.; Botia, J. A.; Guelfi, S.; Collado-Torres, L.; Ryten, M.
10.1101/2023.03.29.534370 — genetics — Posted on 2023-03-30
239 Genetic and environmental contributions to ancestry differences in gene expression in the human brain
Benjamin, K. J.; Chen, Q.; Eagles, N. J.; Huuki-Myers, L. A.; Collado-Torres, L.; Stolz, J. M.; Shin, J. H.; Paquola, A. C.; Hyde, T. M.; Kleinman, J. E.; Jaffe, A. E.; Han, S.; Weinberger, D. R.
10.1101/2023.03.28.534458 — genetics — Posted on 2023-03-30
240 Phenotypic drought stress prediction of European beech (Fagus sylvatica) by genomic prediction and remote sensing
Pfenninger, M.; Langan, L.; Feldmeyer, B.; Fussi, B.; Hoffmann, J.; Granado, R.; Hetzer, J.; Seho, M.; Mellert, K.-H.; Hickler, T.
10.1101/2023.03.29.534688 — evolutionary biology — Posted on 2023-03-30
241 Interleukin-1 regulates follicular T cells during the germinal center reaction
Belbezier, A.; Engeroff, P.; Fourcade, G.; Vantomme, H.; Vaineau, R.; Gouritin, B.; Bellier, B.; Brocheriou, I.; Tchitcheck, N.; Graff-Dubois, S.; Klatzmann, D.
10.1101/2023.03.29.534687 — immunology — Posted on 2023-03-30
242 Natural antibodies as "eat-me" signals for phagocytosis of necrotic cell debris at sites of tissue injury
Mattos, M. S.; Vandendriessche, S.; Schuermans, S.; Feyaerts, L.; Hoevelmeyer, N.; Waisman, A.; Marques, P. E.
10.1101/2023.03.29.533912 — immunology — Posted on 2023-03-30
244 Efficient PCA denoising of spatially correlated MRI data
Henriques, R. N.; Ianus, A.; Novello, L.; Jovicich, J.; Jespersen, S.; Shemesh, N.
10.1101/2023.03.29.534707 — neuroscience — Posted on 2023-03-30
245 Passive endocytosis in model protocells
Zhang, S. J.; Lowe, L. A.; Anees, P.; Krishnan, Y.; Fai, T. G.; Szostak, J. W.; Wang, A.
10.1101/2023.01.07.522792 — biophysics — Posted on 2023-03-30
250 One for all - Human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses
Daniels, A.; Fletcher, S. L.; Kerr, H. E. M.; Kratzel, A.; Kriplani, N.; Craig, N.; Hastie, C. J.; Davies, P.; Digard, P.; Thiel, V.; Tait-Burkard, C.
10.1101/2022.10.25.513760 — microbiology — Posted on 2023-03-30
252 Adolescent binge drinking leads to long lasting changes in cortical microcircuits in mice
Sicher, A. R.; Starnes, W. D.; Griffith, K. R.; Dao, N. C.; Smith, G. C.; Brockway, D. F.; Crowley, N. A.
10.1101/2022.08.02.502367 — neuroscience — Posted on 2023-03-30
253 Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult in mice
Yiew, N. K.; Vazquez, J. H.; Martino, M. R.; Kennon-McGill, S.; Price, J. R.; Allard, F. D.; Yee, E. U.; James, L. P.; McCommis, K. S.; Finck, B. N.; McGill, M. R.
10.1101/2022.06.14.495517 — pharmacology and toxicology — Posted on 2023-03-30
256 Broad and potent neutralizing mAbs are elicited in vaccinated individuals following Delta/BA.1 breakthrough infection
Seow, J.; Shalim, Z. A.; Graham, C.; Kimuda, S.; Pillai, A.; Lechmere, T.; Kurshan, A.; Khimji, A.; Snell, L.; Nebbia, G.; Mant, C.; Waters, A.; Fox, J.; Malim, M. H.; Doores, K. J.
10.1101/2023.03.30.534872 — immunology — Posted on 2023-03-30
257 NETosis Induced by Serum of Patients with COVID-19 is Reduced with Reparixin or Antibodies Against DEK and IL-8
Kilic, I. B.; Yasar, A.; Yalim Camci, I.; Guzel, T.; Karahasan, A.; Yagci, T.; Cine, N.; Kandilci, A.
10.1101/2023.03.30.534873 — immunology — Posted on 2023-03-30
259 Improving mRNA vaccine safety and efficiency with cationized lipid nanoparticle formula
Peng, X.; Liao, G.; Ren, D.; Zhou, Y.; Wu, X.; Lei, Y.; Zhang, Y.; Chen, L.; He, C.; Zhang, Y.; Yin, H.; Yang, G.; Xu, K.
10.1101/2023.03.29.534838 — synthetic biology — Posted on 2023-03-30
260 Virtual histology of Alzheimer's Disease: why are amyloid-β plaques visible with X-ray phase-contrast imaging?
Chourrout, M.; Sandt, C.; Weitkamp, T.; Ducic, T.; Meyronet, D.; Baron, T.; Klohs, J.; Rama, N.; Boutin, H.; Singh, S.; Olivier, C.; Wiart, M.; Brun, E.; Bohic, S.; Chauveau, F.
10.1101/2022.09.27.509706 — biophysics — Posted on 2023-03-30
261 SODAR: managing multi-omics study data and metadata
Nieminen, M.; Stolpe, O.; Kuhring, M.; Weiner, J.; Pett, P.; Beule, D.; Holtgrewe, M.
10.1101/2022.08.19.504516 — bioinformatics — Posted on 2023-03-30
262 Shifting the selectivity of pyridopyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily
Rak, M.; Tesch, R.; Berger, L. M.; Shevchenko, E.; Raab, M.; Tjaden, A.; Zhubi, R.; Balourdas, D.-I.; Joerger, A. C.; Poso, A.; Kraemer, A.; Elson, L.; Lucic, A.; Kronenberger, T.; Hanke, T.; Strebhardt, K.; Sanhaji, M.; Knapp, S.
10.1101/2023.03.24.534094 — biochemistry — Posted on 2023-03-30
265 The Adaptor Protein 2 (AP2) complex modulates habituation and behavioral selection across multiple pathways and time windows
Zuniga Mouret, R.; Greenbaum, J. P.; Doll, H. M.; Brody, E. M.; Iacobucci, E. L.; Roland, N. C.; Simamora, R. C.; Ruiz, I.; Seymour, R.; Ludwick, L.; Groneberg, A. H.; Marques, J. C.; Laborde, A.; Rajan, G.; Del Bene, F.; Orger, M. B.; Jain, R. A.
10.1101/2022.05.20.492863 — neuroscience — Posted on 2023-03-30
266 Characterisation of the SUF FeS cluster machinery in the amitochondriate eukaryote Monocercomonoides exilis
Pena-Diaz, P.; Braymer, J. J.; Vacek, V.; Zelena, M.; Lometto, S.; Hrdy, I.; Treitli, S. C.; Hochberg, G.; Py, B.; Lill, R.; Hampl, V.
10.1101/2023.03.30.534840 — biochemistry — Posted on 2023-03-30
267 Mitochondrial H2O2 release does not directly cause genomic DNA damage.
van Soest, D. M. K.; Polderman, P. E.; den Toom, W. T.; Zwakenberg, S.; De Henau, S.; Burgering, B. M. T.; Dansen, T. B.
10.1101/2023.03.29.534749 — cell biology — Posted on 2023-03-30
272 APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1
Ikeda, T.; Shimizu, R.; Nasser, H.; Carpenter, M. A.; Cheng, A. Z.; Brown, W. L.; Sauter, D.; Harris, R. S.
10.1101/2023.03.28.534666 — microbiology — Posted on 2023-03-30
275 Click-to-Release: Cleavable Radioimmunoimaging with 89Zr-DFO-Trans-Cyclooctene-Trastuzumab Increases Tumor-to-Blood Ratio
Vlastara, M.; Rossin, R.; Hoeben, F. J.; de Roode, K. E.; Boswinkel, M.; Kleijn, L. H.; Nagarajah, J.; Rijpkema, M.; Robillard, M. S.
10.1101/2023.03.27.534155 — pharmacology and toxicology — Posted on 2023-03-30
276 Optical control of cardiac rhythm by in vivo photoactivation of an ERG channel peptide inhibitor
Montnach, J.; Millet, H.; Persello, A.; Meudal, H.; De Waard, S.; Mesirca, P.; Ribeiro, B.; Richard, J.; Hivonnait, A.; Tessier, A.; Lauzier, B.; Charpentier, F.; Mangoni, M. E.; Landon, C.; jopling, C.; De Waard, M.
10.1101/2023.03.23.534038 — pharmacology and toxicology — Posted on 2023-03-30
277 Genetic structure and genome-wide association study of the traditional Kazakh horses
Pozharskiy, A.; Abdrakhmanova, A.; Beishova, I.; Shamshidin, A.; Nametov, A.; Ulyanova, T.; Bekova, G.; Kikebayev, N.; Kovalchuk, A.; Ulyanov, V.; Turabayev, A.; Khusnitdinova, M.; Zhambakin, K.; Sapakhova, Z.; Shamekova, M.; Gritsenko, D.
10.1101/2023.03.29.534422 — genetics — Posted on 2023-03-30
279 Sleep deprivation measured by voice analysis
Thoret, E.; Andrillon, T.; Gauriau, C.; Leger, D.; Pressnitzer, D.
10.1101/2022.11.17.516913 — neuroscience — Posted on 2023-03-30
280 Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington disease
Birolini, G.; Valenza, M.; Ottonelli, I.; Talpo, F.; Minoli, L.; Cappelleri, A.; Bombaci, M.; Caccia, C.; Canevari, C.; Trucco, A.; Leoni, V.; Passoni, A.; Favagrossa, M.; Nucera, M. R.; Colombo, L.; Paltrinieri, S.; Bagnati, R.; Duskey, J. T.; Caraffi, R.; Vandelli, M. A.; Taroni, F.; Salmona, M.; Scanziani, E.; Biella, G.; Ruozi, B.; Tosi, G.; Cattaneo, E.
10.1101/2022.08.26.505426 — neuroscience — Posted on 2023-03-30
286 Altered neurological and neurobehavioral phenotypes in a mouse model of the recurrent KCNB1-p.R306C voltage-sensor variant
Kang, S. K.; Hawkins, N. A.; Echevarria-Cooper, D. M.; Baker, E. M.; Dixon, C. J.; Speakes, N.; Kearney, J. A.
10.1101/2023.03.29.534736 — neuroscience — Posted on 2023-03-30
288 Unlocking de novo antibody design with generative artificial intelligence
Shanehsazzadeh, A.; Bachas, S.; McPartlon, M.; Kasun, G.; Sutton, J. M.; Steiger, A. K.; Shuai, R.; Kohnert, C.; Rakocevic, G.; Gutierrez, J. M.; Chung, C.; Luton, B. K.; Diaz, N.; Levine, S.; Alverio, J.; Knight, B.; Radach, M.; Morehead, A.; Bateman, K.; Spencer, D. A.; McDargh, Z.; Cejovic, J.; Kopec-Belliveau, G.; Haile, R.; Yassine, E.; McCloskey, C.; Natividad, M.; Chapman, D.; Bennett, J.; Hossain, J.; Ventura, A. B.; Canales, G. M.; Gowda, M.; Jackson, K. A.; Stanton, J. T.; Ura, M.; Stojanovic, L.; Yapici, E.; Moran, K.; Caguiat, R.; Brown, A.; Abdulhaqq, S.; Guo, Z.; Klug, L. R.; Gan
10.1101/2023.01.08.523187 — synthetic biology — Posted on 2023-03-29
289 Virulence shift in Type X Toxoplasma gondii: natural cross QTL identifies ROP33 as rodent Vir locus
Kennard, A.; Miller, M. A.; Khan, A.; Quinones, M.; Miller, N.; Sundar, N.; James, E. R.; Greenwald, K.; Roos, D. S.; Grigg, M. E.
10.1101/2021.03.31.437793 — molecular biology — Posted on 2023-03-29
290 Transkingdom Network Analysis (TkNA): a systems approach inferring causal factors underlying host-microbiota interactions.
Newman, N. K.; Macovsky, M. S.; Rodrigues, R. R.; Bruce, A. M.; Pederson, J. W.; Patil, S. S.; Padiadpu, J.; Dzutsev, A. K.; Shulzhenko, N.; Trinchieri, G.; Brown, K. S.; Morgun, A.
10.1101/2023.02.22.529449 — systems biology — Posted on 2023-03-29
291 Data-driven precision nutrition improves clinical outcomes and risk scores for IBS, depression, anxiety, and T2D
Connell, J.; Toma, R.; Ho, C.; Shen, N.; Moura, P.; Le, T.; Patridge, E.; Antoine, G.; Keiser, H.; Julian, C.; Naidoo, U.; Tanton, D.; Banavar, G.; Vuyisich, M.
10.1101/2021.04.24.441290 — systems biology — Posted on 2023-03-29
292 Using genomic scars to select immunotherapy beneficiaries in advanced non-small cell lung cancer
Donker, H. C.; van Es, B.; Tamminga, M.; Lunter, G. A.; van Kempen, L. C. L. T.; Schuuring, E.; Hiltermann, T. J. N.; Groen, H. J. M.
10.1101/2022.09.23.509152 — cancer biology — Posted on 2023-03-29
297 Nanoscale 3D DNA tracing in single human cells visualizes loop extrusion directly in situ
Beckwith, K. S.; Oedegaard Fougner, O.; Morero, N. R.; Barton, C.; Schueder, F.; Tang, W.; Alexander, S.; Peters, J.-M.; Jungmann, R.; Birney, E.; Ellenberg, J.
10.1101/2021.04.12.439407 — cell biology — Posted on 2023-03-29
298 Compression-dependent microtubule reinforcement comprises a mechanostat which enables cells to navigate confined environments
Ju, R. J.; Falconer, A. D.; Dean, K. M.; Fiolka, R. P.; Sester, D. P.; Nobis, M.; Timpson, P.; Lomakin, A. J.; Danuser, G.; White, M. D.; Oelz, D. B.; Haass, N. K.; Stehbens, S. J.
10.1101/2022.02.08.479516 — cell biology — Posted on 2023-03-29
300 Novel mRNA-based VP8* vaccines against rotavirus are highly immunogenic in rodents
Roier, S.; Prasad, V. M.; McNeal, M. M.; Lee, K. K.; Petsch, B.; Rauch, S.
10.1101/2023.03.29.534747 — immunology — Posted on 2023-03-29
302 Hippocampal damage causes retrograde amnesia for objects' visual, but not odour, properties
Lacoursiere, S. G.; McAllister, B. B.; Hadikin, C.; Tschetter, W. W.; Lehmann, H.; Sutherland, R. J.
10.1101/2022.09.14.508050 — neuroscience — Posted on 2023-03-29
305 Regulation of hair cell and stomatal size by a hair-cell specific peroxidase in the grass Brachypodium distachyon
Nunes, T. D.; Berg, L. S.; Slawinska, M. W.; Zhang, D.; Redt, L.; Sibout, R.; Vogel, J. P.; Laudencia-Chingcuanco, D.; Jesenofsky, B.; Lindner, H.; Raissig, M. T.
10.1101/2022.07.03.498611 — plant biology — Posted on 2023-03-29
309 Towards high-throughput parallel imaging and single-cell transcriptomics of microbial eukaryotic plankton
Grujcic, V.; Saarenpaa, S.; Sundh, J.; Sennblad, B.; Norgren, B.; Latz, M.; Giacomello, S.; Foster, R. A.; Andersson, A. F.
10.1101/2023.03.29.534285 — genomics — Posted on 2023-03-29
311 Cyanobacteria using urea as a nitrogen source can overcome acid stress
LI, S.-Q.; Huang, H.; SUN, T.-R.; GAO, H.-Y.; WANG, X.-W.; FU, F.-X.; A. HUTCHINS, D.; JIANG, H.-B.
10.1101/2023.03.29.534730 — ecology — Posted on 2023-03-29
312 Glycosylation differentially affects immune cell-specific tetraspanins CD37 and CD53
van Deventer, S. J.; Hoogvliet, I. A.; van de Voort, M.; Arnold, F.; van Spriel, A.
10.1101/2023.03.29.534715 — cell biology — Posted on 2023-03-29
313 Abnormal autophagy is a critical mechanism in TANGO2-related rhabdomyolysis
Montealegre, S.; de Calbiac, H.; Straube, M.; Debruge, H.; Chentout, L.; Ciura, S.; Imbard, A.; Le Guillou, E.; Marian, A.; Goudin, N.; Caccavelli, L.; Fabrega, S.; Hubas, A.; van Endert, P.; Dupont, N.; Diana, J.; Kabashi, E.; de Lonlay, P.
10.1101/2023.03.29.534583 — cell biology — Posted on 2023-03-29
314 Transposon-encoded nucleases use guide RNAs to selfishly bias their inheritance
Meers, C.; Le, H.; Pesari, S. R.; Hoffmann, F. T.; Walker, M. W. G.; Gezelle, J.; Sternberg, S. H.
10.1101/2023.03.14.532601 — molecular biology — Posted on 2023-03-29
317 Parvalbumin neurons, temporal coding, and cortical noise in complex scene analysis
Nocon, J. C.; Gritton, H. J.; James, N. M.; Mount, R. A.; Qu, Z.; Han, X.; Sen, K.
10.1101/2021.09.11.459906 — neuroscience — Posted on 2023-03-29
318 NEURD: automated proofreading and feature extraction for connectomics
Celii, B.; Papadopoulos, S.; Ding, Z.; Fahey, P. G.; Wang, E.; Papadopoulos, C.; Kunin, A.; Patel, S.; Bae, J. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Cobos, E.; Dorkenwald, S.; Elabbady, L.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Schneider-Mizell, C. M.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yu, S.-c.; Yin, W.; Xenes, D.; Kitchell, L. M.; Rivlin, P. K.; Rose, V. A.; Bishop
10.1101/2023.03.14.532674 — neuroscience — Posted on 2023-03-29
319 Distinct feedforward and feedback pathways for cell-type specific attention effects
Spyropoulos, G.; Schneider, M.; van Kempen, J.; Gieselmann, M. A.; Thiele, A.; Vinck, M.
10.1101/2022.11.04.515185 — neuroscience — Posted on 2023-03-29
320 Decision-making processes in perceptual learning depend on effectors
Ivanov, V.; Manenti, G.; Sudmann, S. S.; Kagan, I.; Schwiedrzik, C. M.
10.1101/2022.06.29.498152 — neuroscience — Posted on 2023-03-29
321 Regional and LTP-Dependent Variation of Synaptic Information Storage Capacity in Rat Hippocampus
Samavat, M.; Bartol, T. M.; Bromer, C.; Bowden, J. B.; Hubbard, D. D.; Hanka, D. C.; Kuwajima, M.; Mendenhall, J. M.; Parker, P. H.; Abraham, W. C.; Harris, K. M.; Sejnowski, T. J.
10.1101/2022.08.29.505464 — neuroscience — Posted on 2023-03-29
322 Specific ABA-independent tomato transcriptome reprogramming under abiotic stress combination
Pardo-Hernandez, M.; Martinez-Lorente, S. E.; Marti-Guillen, J. M.; Arbona, V.; Simon, I.; Rivero, R. M.
10.1101/2023.03.29.534684 — plant biology — Posted on 2023-03-29
323 Targeting wild-type IDH1 enhances chemosensitivity in pancreatic cancer
Zarei, M.; Hajihassani, O.; Hue, J. J.; Graor, H. J.; Rothermel, L. D.; Winter, J. M.
10.1101/2023.03.29.534596 — cancer biology — Posted on 2023-03-29
332 CsrA Shows Selective Regulation of sRNA-mRNA Networks
Simmons, T. R.; Rojano-Nisimura, M.; Leistra, A. N.; Mihailovic, M. K.; Buchser, R.; Ekdahl, A. M.; Joseph, I.; Curtis, N. C.; Contreras, L. M.
10.1101/2023.03.29.534774 — molecular biology — Posted on 2023-03-29
333 Deciphering novel TCF4-driven molecular origins and mechanisms underlying a common triplet repeat expansion-mediated disease
Bhattacharyya, N.; Hafford-Tear, N. J.; Sadan, A. N.; Szabo, A.; Chai, N.; Zarouchlioti, C.; Jedlickova, J.; Leung, S. K.; Liao, T.; Dudakova, L.; Skalicka, P.; Parekh, M.; Jeffries, A. R.; Cheetham, M. E.; Muthusamy, K.; Hardcastle, A. J.; Pontikos, N.; Liskova, P.; Tuft, S. J.; Davidson, A. E.
10.1101/2023.03.29.534731 — molecular biology — Posted on 2023-03-29
335 MORC2 restriction factor silences HIV proviral expression
Lasserre, A.; Marie, S.; Morel, M.; Martin, M. M.; Legrand, A.; Vauthier, V.; Cimarelli, A.; Etienne, L.; Margottin-Goguet, F.; Matkovic, R.
10.1101/2023.03.29.534756 — microbiology — Posted on 2023-03-29
341 Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple epitopes
Hurtado, J.; Rogers, T. F.; Jaffe, D. B.; Adams, B.; Bangaru, S.; Garcia, E.; Capozzola, T.; Messmer, T.; Sharma, P.; Song, G.; Beutler, N.; He, W.; Dueker, K.; Musharrafieh, R.; Stubbington, M. T. J.; Burton, D.; Andrabi, R.; Ward, A.; McDonnell, W. J.; Briney, B.
10.1101/2023.03.28.534602 — immunology — Posted on 2023-03-29
342 Competence for transcellular infection in the root cortex involves a post-replicative, cell-cycle exit decision in Medicago truncatula
Batzenschlager, M.; Lace, B.; Zhang, N.; Su, C.; Egli, S.; Krohn, P.; Salfeld, J.; Ditengou, F. A.; Laux, T.; Ott, T.
10.1101/2023.03.28.534635 — plant biology — Posted on 2023-03-29
343 TTG2 defines trichome cell shape by modulating microtubules and actin cytoskeleton in Arabidopsis
An, L.; Liu, L.; Cao, W.; Yuan, L.; Yang, L.; Wang, Y.; Zhang, C.; Wang, D.; Wang, W.; Zhang, H.; Schiefelbein, J.; Yu, F.
10.1101/2023.03.29.534767 — developmental biology — Posted on 2023-03-29
344 Two haplotype-resolved genomes of highly heterozygous AAB allotriploid bananas provide insights into subgenome asymmetric evolution and banana wilt control
Xie, W.; Zheng, Y.; He, W.; Bi, F.; Li, Y.; Dou, T.; Zhou, R.; Guo, Y.; Deng, G.; Zhang, W.; Yuan, M.; Sanz-Jimenez, P.; Zhu, X.; Xu, X.; Zhou, Z.; Zhou, Z.; Feng, J.; Liu, S.; Li, C.; Yang, Q.; Hu, C.; Gao, H.; Dong, T.; Dang, J.; Guo, Q.; Cai, W.; Zhang, J.; Yi, G.; Song, J.; Sheng, O.; Chen, L.
10.1101/2023.03.28.534356 — plant biology — Posted on 2023-03-29
345 ZEB1-dependent modulation of fibroblast polarization governs inflammation and immune checkpoint blockade sensitivity in colorectal cancer
Schuhwerk, H.; Menche, C.; Armstark, I.; Gupta, P.; Fuchs, K.; van Roey, R.; Mosa, M. H.; Geppert, C. I.; Baerthel, S.; Saur, D.; Greten, F. R.; Brabletz, S.; Brabletz, T.; Farin, H. F.; Stemmler, M. P.
10.1101/2023.03.28.534565 — cancer biology — Posted on 2023-03-29
347 Harnessing genetic variations improving seedling vigor for successful crop establishment in deep sown direct-seeded rice
Sandhu, N.; Ankush, A. P.; Singh, J.; Raigar, O. P.; Bains, S.; Jindal, T.; Singh, M. P.; Sethi, M.; Pruthi, G.; Augustine, G.; Verma, V. K.; Goyal, S.; Kumar, A.; Panwar, H.; Sihag, M. K.; Kaur, R.; Kurup, S.; Kumar, A.
10.1101/2023.03.28.534621 — genomics — Posted on 2023-03-29
349 Metabolic regulation of misfolded protein import into mitochondria
Wang, Y.; Ruan, L.; Zhu, J.; Zhang, X.; Chang, A.; Tomaszewski, A.; Li, R.
10.1101/2023.03.29.534670 — cell biology — Posted on 2023-03-29
350 Morphogen-driven human iPSCs differentiation in 3D in vitro models of gastrulation is precluded by physical confinement.
Alsehli, H. S.; Roy, E.; Williams, T.; Kuziola, A.; Guo, Y.; Green, J. B.; Gentleman, E.; Danovi, D.
10.1101/2023.03.29.534685 — cell biology — Posted on 2023-03-29
355 Cross-kingdom anti-inflammatory effects of fungal melanin on airway epithelium by post-translational blockade of chemokine secretion
Reedy, J. L.; Crossen, A. J.; Ward, R. A.; Reardon, C. M.; Harding, H. B.; Basham, K. J.; Rajagopal, J.; Vyas, J. M.
10.1101/2023.03.28.534632 — immunology — Posted on 2023-03-29
356 Methylglyoxal is the main culprit to impairing neuronal function: mediated through tryptophan depletion.
Samsuzzaman, M.; Lee, J. H.; Hong, S.-M.; Park, H. J.; Chang, K.-A.; Kim, H.-B.; Park, M. G.; Eo, H.; Oh, M. S.; Kim, S. Y.
10.1101/2023.03.29.534483 — neuroscience — Posted on 2023-03-29
360 PERK arm of UPR selectively regulates ferroptosis in colon cancer cells by modulating the expression of SLC7A11 (System Xc-)
Saini, K. K.; Chaturvedi, P.; Sinha, A.; Singh, M. P.; Khan, M. A.; Verma, A.; Nengroo, M. A.; Satrusal, S. R.; Meena, S.; Singh, A.; Srivastava, S.; Sarkar, J.; Datta, D.
10.1101/2023.03.28.534659 — cancer biology — Posted on 2023-03-29
366 Nightmare or delight: taxonomic circumscription meets reticulate evolution in the phylogenomic era
Jin, Z.-t.; Hodel, R. G. J.; Ma, D.-K.; Wang, H.; Liu, G.; Ren, C.; Ge, B.; Fan, Q.; Jin, S.-H.; Xu, C.; Wu, J.; Liu, B.-B.
10.1101/2023.03.28.534649 — evolutionary biology — Posted on 2023-03-29
367 Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases
Venkat, A.; Watterson, G.; Byrne, D. P.; Boyle, B. O.; Shrestha, S.; Gravel, N.; Fairweather, E. E.; Daly, L. A.; Bunn, C.; Yeung, W.; Aggarwal, I.; Katiyar, S.; Eyers, C. E.; Eyers, P.; Kannan, N.
10.1101/2023.03.29.534689 — evolutionary biology — Posted on 2023-03-29
373 Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression
Nguyen, H. P.; Sheng, R.; Murray, E.; Ito, Y.; Bruck, M.; Biellak, C.; An, K.; Lynce, F.; Dillon, D. A.; Magbanua, M. J. M.; Huppert, L. A.; Hammerlindl, H.; Esserman, L.; Rosenbluth, J. M.; Ahituv, N.
10.1101/2023.03.28.534564 — cancer biology — Posted on 2023-03-29
374 Learning transcriptional and regulatory dynamics driving cancer cell plasticity using neural ODE-based optimal transport
Tong, A.; Kuchroo, M.; Gupta, S.; Venkat, A.; Perez San Juan, B.; Rangel, L.; Zhu, B.; Lock, J. G.; Chaffer, C.; Krishnaswamy, S.
10.1101/2023.03.28.534644 — cancer biology — Posted on 2023-03-29
376 Structural basis of membrane targeting and coatomer assembly by human GBP1
Kuhm, T. I.; Gross, L.; de Agrela Pinto, C.; Huber, S. T.; Taisne, C.; Giannopoulou, E. A.; Pardon, E.; Steyaert, J.; Tans, S. J.; Jakobi, A. J.
10.1101/2023.03.28.534355 — biophysics — Posted on 2023-03-29
382 High-level production of nervonic acid in the oleaginous yeast Yarrowia lipolytica by systematic metabolic engineering
Su, H.; Shi, P.; Shen, Z.; Meng, H.; Meng, Z.; Han, X.; chen, Y.; Fan, W.; Fa, Y.; Yang, C.; Li, F.; Wang, S.
10.1101/2023.03.28.534371 — bioengineering — Posted on 2023-03-29
383 A Universal Method for Crossing Molecular and Atlas Modalities using Simplex-Based Image Varifolds and Quadratic Programming
Stouffer, K. M.; Trouve, A.; Younes, L.; Kunst, M.; Ng, L.; Zeng, H.; Anant, M.; Fan, J.; Kim, Y.; Miller, M. I.
10.1101/2023.03.28.534622 — bioengineering — Posted on 2023-03-29
387 Conserved satellite DNA motif and lack of interstitial telomeric sites in highly rearranged African Nothobranchius killifish karyotypes
Luksikova, K.; Pavlica, T.; Altmanova, M.; Stundlova, J.; Pelikanova, S.; Simanovsky, S. A.; Krysanov, E. Y.; Jankasek, M.; Hirman, M.; Reichard, M.; Rab, P.; Sember, A.
10.1101/2023.03.28.534604 — genetics — Posted on 2023-03-29
389 Long-term evolution of proliferating yeast cells using the eVOLVER platform
Garcia-Ruano, D.; Jain, A.; Heins, Z. J.; Wong, B. G.; Wolle, E. Y.; Khalil, A. S.; Coudreuse, D.
10.1101/2023.03.28.534552 — evolutionary biology — Posted on 2023-03-29
391 Bayesian joint species distribution model selection for community-level prediction
Itter, M. S.; Kaarlejärvi, E.; Laine, A.-L.; Hamberg, L.; Tonteri, T.; Vanhatalo, J.
10.1101/2022.05.03.490480 — ecology — Posted on 2023-03-29
392 Identifying keystone species in microbial communities using deep learning
Wang, X.-W.; Sun, Z.; Jia, H.; Michel-Mata, S.; Angulo, M. T.; Dai, L.; He, X.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2023.03.15.532858 — microbiology — Posted on 2023-03-29
393 Alzheimer's Disease associations of ferritin and glutathione with oxidative damage and neuronal loss
Thorwald, M.; Godoy-Lugo, J. A.; Silva, J.; Head, E.; O'Day, P. A.; Morgan, T. E.; Forman, H. J.; Finch, C. E.
10.1101/2023.03.28.534324 — neuroscience — Posted on 2023-03-29
394 Tools and methods for high-throughput single-cell imaging with the mother machine
Thiermann, R.; Sandler, M.; Ahir, G.; Sauls, J. T.; Schroeder, J. W.; Brown, S. D.; Le Treut, G.; Si, F.; Li, D.; Wang, J.; Jun, S.
10.1101/2023.03.27.534286 — systems biology — Posted on 2023-03-29
397 Self-eating while being eaten: Elucidating the relationship between aphid feeding and the plant autophagy machinery in Arabidopsis leaves
Hao, L. K.; Dangol, A.; Shavit, R.; Pitt, W. J.; Nalam, V.; Brotman, Y.; Michaeli, S.; Peled-Zehavi, H.; Tzin, V.
10.1101/2023.03.28.534380 — plant biology — Posted on 2023-03-29
401 Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer
Freshour, S. L.; Chen, T. H.-P.; Fisk, B.; Shen, H.; Mosior, M.; Skidmore, Z. L.; Fronick, C.; Bolzenius, J. K.; Griffith, O. L.; Arora, V. K.; Griffith, M.
10.1101/2023.03.28.534561 — cancer biology — Posted on 2023-03-29
402 The immune response to a fungus in pancreatic cancer samples
Rabinowitz, I.; Brayer, K.; Cingam, S.; Hanson, J.; Martinez, C.; Ness, S.
10.1101/2023.03.28.534606 — cancer biology — Posted on 2023-03-29
403 Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion
Han, S. J.; Jain, P.; Gilad, Y.; Xia, Y.; Sung, N.; Park, M. J.; Dean, A. M.; Lanz, R. B.; Xu, J.; Dacso, C. C.; Lonard, D. M.; O'Malley, B. W.
10.1101/2023.03.28.534575 — cancer biology — Posted on 2023-03-29
404 The G protein-coupled receptor TBXA2R activates ERMs to promote motility, invasion, and metastasis of triple-negative breast cancer cells.
Leguay, K.; Naffati, O.; He, Y. Y.; Rogue, M.; Tesniere, C.; Gombos, E. M.; Kuasne, H.; Gaboury, L.; Le Gouill, C.; Meloche, S.; Bouvier, M.; Carreno, S.
10.1101/2023.03.28.534587 — cancer biology — Posted on 2023-03-29
409 Micro to macro scale analysis of the intact human renal arterial tree with Synchrotron Tomography
Rahmani, S.; Jafree, D. J.; Lee, P. D.; Tafforeau, P.; Jacob, J.; Bellier, A.; Ackermann, M.; Jonigk,, D. D.; Shipley, R. J.; Long, D. A.; Walsh, C. L.
10.1101/2023.03.28.534566 — bioengineering — Posted on 2023-03-29
411 Visual integration of omics data to improve 3D models of fungal chromosomes
Poinsignon, T.; Gallopin, M.; Grognet, P.; Malagnac, F.; Lelandais, G.; Poulain, P.
10.1101/2023.03.28.534549 — genomics — Posted on 2023-03-29
412 A reference assembly for the legume cover crop, hairy vetch (Vicia villosa)
Fuller, T.; Koch, L. M.; Kucek, L. K.; Ali, S.; Mangelson, H.; Hernandez, T.; Smith, T. P. L.; Bickhart, D. M.; Riday, H.; Sullivan, M. L.
10.1101/2023.03.28.534423 — genomics — Posted on 2023-03-29
415 ChoruMM: a versatile multi-components mixed model for bacterial-GWAS
Frouin, A.; Laporte, F.; Hafner, L.; Maury, M.; McCaw, Z. R.; Henches, L.; Julienne, H.; Chikhi, R.; Lecuit, M.; Aschard, H.
10.1101/2023.03.28.534531 — genetics — Posted on 2023-03-29
416 Genetics of Latin American Diversity (GLAD) Project: insights into population genetics and association studies in recently admixed groups in the Americas
Borda, V.; Loesch, D. P.; Guo, B.; Laboulaye, R.; Veliz-Otani, D.; French-Kwawu, J. N.; Peixoto Leal, T.; Gogarten, S. M.; Ikpe, S.; Gouveia, M. H.; Mendes, M.; Abecasis, G. R.; Alvim, I.; Arboleda-Bustos, C. E.; Arboleda, G.; Arboleda, H.; Barreto, M. L.; Barwick, L.; Bezzera, M. A.; Blangero, J.; Borges, V.; Caceres, O.; Cai, J.; Chana-Cuevas, P.; Chen, Z.; Custer, B.; Dean, M.; Dinardo, C.; Domingos, I.; Duggirala, R.; Dieguez, E.; Fernandez, W.; Ferraz, H. B.; Gilliland, F. D.; Guio, H.; Horta, B.; Curran, J. E.; Johnsen, J. M.; Kaplan, R. C.; Kelly, S.; Kenny, E. E.; Konkle, B. A.; Kooper
10.1101/2023.01.07.522490 — genetics — Posted on 2023-03-29
421 Hypothesis: Colony-forming activity of pluripotent stem cell-derived hepatocyte-like cells for stem cell assay
Ite, K.; Toyoda, M.; Akiyama, S.; Enosawa, S.; Yoshioka, S.; Yukitake, T.; Yamazaki-Inoue, M.; Tatsumi, K.; Akutsu, H.; Nishina, H.; Kimura, T.; Ohtani, N.; Nakazawa, A.; Fukuda, A.; Kasahara, M.; UMEZAWA, A.
10.1101/2021.11.30.470519 — cell biology — Posted on 2023-03-29
423 GRAPHENE OXIDE AS A NOVEL IMMUNOTHERAPY TOOL FOR THE MODULATION OF MYELOID-DERIVED SUPPRESSOR CELL ACTIVITY IN THE CONTEXT OF MULTIPLE SCLEROSIS
Camacho-Toledano, C.; Machin-Diaz, I.; Lebron-Galan, R.; Gonzalez-Mayorga, A.; Palomares, F. J.; Serrano, M. C.; Clemente, D.
10.1101/2023.03.28.534540 — immunology — Posted on 2023-03-29
424 Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection
Guenthoer, J.; Lilly, M.; Starr, T. N.; Dadonaite, B.; Lovendahl, K. N.; Croft, J. T.; Stoddard, C. I.; Chohan, V.; Ding, S.; Ruiz, F.; Kopp, M. S.; Finzi, A.; Bloom, J. D.; Chu, H. Y.; Lee, K. K.; Overbaugh, J.
10.1101/2022.12.15.520606 — immunology — Posted on 2023-03-29
427 Terpenes from Cannabis sativa Induce Antinociception in Mouse Chronic Neuropathic Pain via Activation of Spinal Cord Adenosine A2A Receptors
Schwarz, A.; Keresztes, A.; Bui, T.; Hecksel, R.; Pena, A.; Lent, B.; Gao, Z.-G.; Gamez-Rivera, M.; Seekins, C.; Chou, K.; Appel, T.; Jacobson, K. A.; Al-Obeidi, F.; Streicher, J. M.
10.1101/2023.03.28.534594 — neuroscience — Posted on 2023-03-29
431 Analytical Comparability to Evaluate Impact of Manufacturing Changes of ARX788, an Anti-HER2 ADC in Late-Stage Clinical Development
Ramprasad, M. P.; Yu, W.; Pal, M.; Chen, C.; Paruchuri, S.; Skidmore, L.; Knudsen, N.; Allen, M.; Buechler, Y.
10.1101/2023.03.27.534450 — cancer biology — Posted on 2023-03-29
432 TET2 lesions enhance the aggressiveness of CEBPA-mutant AML by rebalancing GATA2 expression
Heyes, E.; Wilhelmson, A. S.; Wenzel, A.; Manhart, G.; Eder, T.; Schuster, M. B.; Rzepa, E.; Pundhir, S.; D'Altri, T.; Gentil, C.; Meggendorfer, M.; Schwaller, J.; Haferlach, T.; Grebien, F.; Porse, B. T.
10.1101/2023.03.28.534511 — cancer biology — Posted on 2023-03-29
434 A quantitative description for optical mass measurement of single biomolecules
Becker, J.; Peters, J. S.; Crooks, I.; Helmi, S.; Synakewicz, M.; Schuler, B.; Kukura, P.
10.1101/2023.03.28.534430 — biophysics — Posted on 2023-03-29
435 Convolutional neural network approach for the automated identification of in cellulo crystals
Kardoost, A.; Schönherr, R.; Deiter, C.; Redecke, L.; Lorenzen, K.; Schulz, J.; de Diego, I.
10.1101/2023.03.28.533948 — biophysics — Posted on 2023-03-29
438 Structural characterization of a novel luciferase-like-monooxygenase from Pseudomonas meliae an in silico approach
Rayhan, M.; Siddiquee, M. F. R.; Shahriar, A.; Ahmed, H.; Mahmud, A. R.; Alam, M. S.; Uddin, M. R.; Acharjee, M.; Shimu, M. S. S.; Shamsir, M. S.; Emran, T. B.
10.1101/2023.03.27.534437 — bioinformatics — Posted on 2023-03-29
443 Deep Active Learning for Robust Biomedical Segmentation
Arikan, M.; Sallo, F.; Montesel, A.; Ahmed, H.; Hagag, A.; Book, M.; Faatz, H.; Cicinelli, M.; Meshkinfamfard, S.; Ongun, S.; Dubis, A.; Lilaonitkul, W.
10.1101/2023.03.28.534521 — bioengineering — Posted on 2023-03-29
444 The structure of the tetraploid sour cherry 'Schattenmorelle' (Prunus cerasus L.) genome reveals insights into its segmental allopolyploid nature
Woehner, T. W.; Emeriewen, O. F.; Wittenberg, A. H. J.; Nijbroek, K.; Wang, R. P.; Blom, E.-J.; Keilwagen, J.; Berner, T.; Hoff, K. J.; Gabriel, L.; Thierfeldt, H.; Almolla, O.; Barchi, L.; Schuster, M.; Lempe, J.; Peil, A.; Flachowsky, H.
10.1101/2023.03.28.534503 — genomics — Posted on 2023-03-29
446 A role for N6-methyldeoxyadenosine in C. elegans mitochondrial genome regulation
Grub, L. K.; Held, J. P.; Hansen, T. J.; Schaffner, S. H.; Canter, M. R.; Malagise, E. M.; Patel, M. R.
10.1101/2023.03.27.534452 — genetics — Posted on 2023-03-29
450 The genomics and evolution of inter-sexual mimicry and female-limited polymorphisms in damselflies
Willink, B.; Tunström, K.; Nilen, S.; Chikhi, R.; Lemane, T.; Takahashi, M.; Takahashi, Y.; Svensson, E. I.; Wheat, C. W.
10.1101/2023.03.27.532508 — evolutionary biology — Posted on 2023-03-29
454 One does not simply grow well: Performance of grassland plants in home and foreign soil and climate
Aares, K. H.; Bockelie-Rosendahl, T.; Priyadarshi, R.; Pugnaire, F. I.; Schob, C.; Alifriqui, M.; Manrique, E.; Jaakola, L. H.; Brathen, K. A.
10.1101/2023.02.03.526963 — ecology — Posted on 2023-03-29
459 PIEZO1-mediated mechanosensing governs NK cell killing efficiency in 3D
Yanamandra, A. K.; Zhang, J.; Montalvo, G.; Biedenweg, D.; Hoth, M.; Lautenschlaeger, F.; Otto, O.; del Campo, A.; Qu, B.
10.1101/2023.03.27.534435 — immunology — Posted on 2023-03-29
460 Temperature-dependent regulation of Arabidopsis thaliana growth and development by LSM7
Nardeli, S. M.; Zacharaki, V.; Rojas-Murcia, N.; Collani, S.; Wang, K.; Bayer, M.; Schmid, M.; Goretti, D.
10.1101/2023.03.28.534379 — plant biology — Posted on 2023-03-29
462 Myofibrillar malformations that arise in mdx muscle fibers are driven by detyrosinated microtubules
Harriot, A.; Altair-Morris, T.; Venegas, C.; Kallenbach, J.; Pinto, K.; Joca, H.; Moutin, M.-J.; Shi, G.; Ursitti, J.; Grosberg, A.; Ward, C.
10.1101/2023.03.27.534405 — pathology — Posted on 2023-03-29
464 Extensive Dysregulation of SLK Splicing in Cancers Impacts Metastasis
Yang, Y.-Q.; Hu, Y.; Zhang, S.-R.; Li, J.; Guan, J.-W.; Zhang, W.-J.; Sun, Y.; Feng, X.-Y.; Sun, J.; Yang, Y.; Wang, Z.; Wei, H.-H.
10.1101/2022.10.28.514146 — cancer biology — Posted on 2023-03-29
467 Genetic structure and genome-wise association study of traditional Kazakh horses
Pozharskiy, A.; Abdrakhmanova, A.; Beishova, I.; Shamshidin, A.; Nametov, A.; Ulyanova, T.; Bekova, G.; Kikebayev, N.; Kovalchuk, A.; Ulyanov, V.; Turabayev, A.; Khusnitdinova, M.; Zhambakin, K.; Sapakhova, Z.; Shamekova, M.; Gritsenko, D.
10.1101/2023.03.29.534422 — genetics — Posted on 2023-03-29
469 A versatile high-throughput assay based on 3D ring-shaped cardiac tissues generated from human induced pluripotent stem cell derived cardiomyocytes
Seguret, M.; Davidson, P.; Robben, S.; Jouve, C.; Pereira, C.; Cerveau, C.; Le Berre, M.; Rodrigues Ribeiro, R. S.; Hulot, J.-S.
10.1101/2023.03.26.534303 — bioengineering — Posted on 2023-03-29
470 A naturally occurring variant of MBD4 causes maternal germline hypermutation in primates
Stendahl, A.; Sanghvi, R.; Peterson, S.; Ray, K.; Lima, A. C.; Rahbari, R.; Conrad, D.
10.1101/2023.03.27.534460 — genetics — Posted on 2023-03-29
475 Machine-learning based detection of adventitious microbes in T-cell therapy cultures using long read sequencing
Strutt, J. P. B.; Natarajan, M.; Lee, E.; Teo, D. B. L.; Sin, W. X.; Cheung, F. K.-W.; Thazin, K.; Chew, M.; Barone, P. W.; Wolfrum, J. M.; Williams, R. B. H.; Rice, S. A.; Springs, S. L.
10.1101/2022.11.03.514634 — bioinformatics — Posted on 2023-03-29
477 Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities
Garg, V.; Yang, Y.; Nowotschin, S.; Setty, M.; Kuo, Y.-Y.; Sharma, R.; Polyzos, A.; Salataj, E.; Murphy, D.; Jang, A.; Pe'er, D.; Apostolou, E.; Hadjantonakis, A.-K.
10.1101/2023.03.28.534648 — developmental biology — Posted on 2023-03-29
478 Single-Cell Map of Dynamic Multicellular Ecosystem of Radiation-Induced Intestinal Injury
Lu, H.; Yan, H.; Xing, Y.; Ye, Y.; Jiang, S.; Ma, L.; Zuo, H.; Hao, Y.; Yu, C.; Li, Y.; Lu, Y.; Zhou, G.
10.1101/2023.03.06.531402 — cell biology — Posted on 2023-03-29
479 Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development
Wirjanata, G.; Lin, J.; Dziekan, J.; El Sahili, A.; Chung, Z.; Tjia, S.; Zulkifli, N. E. B.; Boentoro, J.; Tham, R.; Lai, S. J.; Go, K.; Han, Y.; Partridge, A.; Olsen, D.; Prabhu, N.; Sobota, R.; Nordlund, P.; Lescar, J.; Bozdech, Z.
10.1101/2021.04.08.438947 — microbiology — Posted on 2023-03-29
481 Stable mammalian serum albumins designed for bacterial expression
Khersonsky, O.; Goldsmith, M.; Zaretsky, I.; Hamer-Rogotner, S.; Dym, O.; Unger, T.; Yona, M.; Fleishman, S. J.
10.1101/2023.03.28.534334 — biochemistry — Posted on 2023-03-29
482 Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements
Hu, Y.; Ma, S.; Kartha, V. K.; Duarte, F. M.; Horlbeck, M.; Zhang, R.; Shrestha, R.; Labade, A.; Kletzien, H.; Meliki, A.; Castillo, A.; Durand, N.; Mattei, E.; Anderson, L. J.; Tay, T.; Earl, A. S.; Shoresh, N.; Epstein, C. B.; Wagers, A.; Buenrostro, J. D.
10.1101/2023.03.28.533945 — genomics — Posted on 2023-03-29
483 Changes in local interaction rules during ontogeny underlie the evolution of collective behavior
Paz, A.; Holt, K. J.; Clarke, A.; Aviles, A.; Abraham, B.; Keene, A. C.; Duboue, E. R.; Fily, Y.; Kowalko, J. E.
10.1101/2023.03.28.534467 — evolutionary biology — Posted on 2023-03-29
484 Human induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation
Piechota, S.; Marchante, M.; Giovannini, A.; Paulsen, B.; Potts, K. S.; Rockwell, G.; Aschenberger, C.; Noblett, A. D.; Figueroa, A. B.; Sanchez, M.; Barrachina, F.; Wiemer, K.; Guzman, L.; Belchin, P.; Pierson Smela, M.; Fortuna, P. R.; Chatterjee, P.; Tran, N. D.; McCulloh, D. H.; Ortiz, S.; Klatsky, P.; Ordonez-Perez, D.; Kramme, C. C.
10.1101/2023.03.27.534479 — developmental biology — Posted on 2023-03-29
486 Improved rescue of immature oocytes obtained from conventional gonadotropin stimulation cycles via human induced pluripotent stem cell-derived ovarian support cell co-culture
Giovannini, A.; Piechota, S.; Marchante, M.; Potts, K. S.; Rockwell, G.; Paulsen, B.; Noblett, A. D.; Figueroa, A. B.; Aschenberger, C.; Kelk, D. A.; Forti, M.; Marcinyshyn, S.; Barrachina, F.; Wiemer, K.; Sanchez, M.; Belchin, P.; Pierson Smela, M.; Fortuna, P. R.; Chatterjee, P.; McCulloh, D. H.; Ordonez-Perez, D.; Klein, J. U.; Kramme, C. C.
10.1101/2023.03.27.534477 — developmental biology — Posted on 2023-03-29
487 Ribosomal protein mutation suppresses gonadal leader cell migration defects in mig-17/ADAMTS mutants in Caenorhabditis elegans
Nishiwaki, K.; Kim, H.-S.; Mitsuzumi, K.; Kondo, S.; Yamaoka, R.; Ihara, S.; Otsuka, H.; Kubota, Y.; Fujiwara, T.; Shibata, Y.
10.1101/2023.03.28.534640 — developmental biology — Posted on 2023-03-29
490 Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing
Itkin, T.; Houghton, S.; Schreiner, R.; Lin, Y.; Badwe, C.; Voisin, V.; Murison, A.; Seyedhassantehrani, N.; Kaufmann, K. B.; Garcia-Prat, L.; Booth, G. T.; Geng, F.; Liu, Y.; Gomez-Salinero, J. M.; Shieh, J.-H.; Redmond, D.; Xiang, J. Z.; Josefowicz, S. Z.; Trapnell, C.; Spencer, J. A.; Zangi, L.; Hadland, B.; Dick, J. E.; Xie, S. Z.; Rafii, S.
10.1101/2023.03.27.534417 — cell biology — Posted on 2023-03-29
491 The novel roles of bovine milk-derived exosomes on skin anti-aging
Ge, X.; Lu, L.; Bai, W.; Wang, M.; Han, C.; Du, H.; Wang, N.; Gao, M.; Li, D.; Dong, F.
10.1101/2023.03.23.532505 — cell biology — Posted on 2023-03-29
492 Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models
Li, J.; Jin, C.; Gustafsson, S.; Rao, A.; Wabitsch, M.; Park, C. Y.; Quertermous, T.; Bielczyk-Maczynska, E.; Knowles, J. W.
10.1101/2023.03.27.534456 — cell biology — Posted on 2023-03-29
497 Integrated platform for multi-scale molecular imaging andphenotyping of the human brain
Park, J.; Wang, J.; Guan, W.; Gjesteby, L. A.; Pollack, D.; Kamentsky, L.; Evans, N. B.; Stirman, J.; Gu, X.; Zhao, C.; Marx, S.; Kim, M. E.; Choi, S. W.; Snyder, M.; Chavez, D.; Su-Arcaro, C.; Tian, Y.; Park, C. S.; Zhang, Q.; Yun, D. H.; Moukheiber, M.; Feng, G.; Yang, X. W.; Keene, C. D.; Hof, P. R.; Ghosh, S. S.; Frosh, M. P.; Brattain, L. J.; Chung, K.
10.1101/2022.03.13.484171 — bioengineering — Posted on 2023-03-29
499 Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2
pan, x.; ye, f.; Ning, P.; Zhang, Z.; Zhang, B.; Chen, G.; Gao, W.; Qiu, C.; Wu, Z.; Gong, K.; Li, J.; Xia, J.; Du, Y.
10.1101/2023.03.28.534513 — cell biology — Posted on 2023-03-29
500 Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology
Tung, V. S. K.; Mathews, F.; Boruk, M.; Suppa, G.; Foronjy, R.; Pato, M.; Pato, C.; Knowles, J. A.; Evgrafov, O. V.
10.1101/2023.03.28.534295 — cell biology — Posted on 2023-03-29
501 Cerebral Cavernous Malformation severity is impacted by distinct forms of Hyaluronic acid in the vascular microenvironment
Yordanov, T. E.; Martinez, M. A. E.; Esposito, T.; Tefft, J. B.; Labzin, L. I.; Stehbens, S. J.; Rowan, A.; Hogan, B. M.; Chen, C. S.; Lauko, J.; Lagendijk, A. K.
10.1101/2023.03.27.534302 — cell biology — Posted on 2023-03-29
506 Decision-making dynamics are predicted by arousal and uninstructed movements
Hulsey, D.; Zumwalt, K.; Mazzucato, L.; McCormick, D. A.; Jaramillo, S.
10.1101/2023.03.02.530651 — neuroscience — Posted on 2023-03-28
507 Schwann cells promote sensory neuron excitability during development
Kantarci, H.; Elvira, P. D.; Thottumkara, A. P.; Iyer, M.; Donovan, L. J.; Ambiel, N.; Dugan, M. Q.; OConnell, E. M.; Granados, A.; Zeng, H.; Saw, N. L.; Lutz, A. B.; Sloan, S. A.; Gray, E. E.; Tran, K. V.; Vichare, A.; Yeh, A. K.; Munch, A. E.; Huber, M.; Agrawal, A.; Morri, M.; Shamloo, M.; Anderson, T. A.; Tawfik, V. L.; Du Bois, J.; Zuchero, J. B.
10.1101/2022.10.31.514415 — neuroscience — Posted on 2023-03-28
510 Intermolecular proteolytic processing of SPRING and Site-1-protease regulate SREBP signaling
Hendrix, S.; Tan, J. M. E.; Ndoj, K.; Valiloo, M.; Zijlstra, L. F.; Ottenhoff, R.; Seidah, N. G.; Loregger, A.; Zelcer, N.
10.1101/2023.03.28.534447 — biochemistry — Posted on 2023-03-28
513 Axial segmentation by iterative mechanical signaling
Wopat, S.; Adhyapok, P.; Daga, B.; Crawford, J. M.; Peskin, B.; Norman, J.; Bagwell, J.; Fogerson, S. M.; Di Talia, S.; Kiehart, D. P.; Charbonneau, P.; Bagnat, M.
10.1101/2023.03.27.534101 — developmental biology — Posted on 2023-03-28
517 BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes
Burdett, H.; Foglizzo, M.; Musgrove, L. J.; Kumar, D.; Clifford, G.; Campbell, L. J.; Heath, G. R.; Zeqiraj, E.; Wilson, M. D.
10.1101/2023.03.28.533771 — molecular biology — Posted on 2023-03-28
519 Mucins shed from the laminated layer in cystic echinococcosis are captured by Kupffer cells via the lectin receptor Clec4F
Barrios, A. A.; Mouhape, C.; Schreiber, L.; Zhang, L.; Nell, J.; Suarez-Martins, M.; Schlapp, G.; Meikle, M. N.; Mulet, A. P.; Hsu, T.-L.; Hsieh, S.-L.; Mourglia-Ettlin, G.; Gonzalez, C.; Crispo, M.; Barth, T. F. E.; Casaravilla, C.; Jenkins, S. J.; Diaz, A.
10.1101/2022.10.06.511139 — immunology — Posted on 2023-03-28
520 A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Carhart-Harris, R. L.; Williams, G. B.; Craig, M. M.; Finoia, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2020.11.25.398081 — neuroscience — Posted on 2023-03-28
521 Accumulation of m6A exhibits stronger correlation with MAPT than beta-amyloid pathology in an APP NL-G-F /MAPT P301S mouse model of Alzheimer's disease
Jiang, L.; Roberts, R.; Wong, M.; Zhang, L.; Webber, C. J.; Kilci, A.; Jenkins, M.; Rashad, S.; Sun, J.; Dedon, P.; Daley, S. A.; Xia, W.; Ortiz, A. R.; Dorrian, L.; Sado, T. C.; Saido, T.; Wolozin, B.
10.1101/2023.03.28.534515 — neuroscience — Posted on 2023-03-28
522 Shedding light on human olfaction: electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium
Hernandez-Clavijo, A.; Sanchez-Trivino, C. A.; Guarneri, G.; Ricci, C.; Mantilla-Esparza, F. A.; Gonzalez-Velandia, K. Y.; Boscolo-Rizzo, P.; Tofanelli, M.; Bonini, P.; Dibattista, M.; Tirelli, G.; Menini, A.
10.1101/2023.03.27.534398 — neuroscience — Posted on 2023-03-28
525 Adaptable, Turn-On Monobody (ATOM) Fluorescent Biosensors for Multiplexed Detection in Cells
Sekhon, H.; Ha, J.-H.; Presti, M.; Procopio, S. B.; Mirsky, P. O.; John, A. M.; Loh, S. N.
10.1101/2023.03.28.534597 — synthetic biology — Posted on 2023-03-28
526 Therapeutic targeting of ACLY in T-ALL in vivo
da Silva-Diz, V.; Singh, A.; Lancho, O.; Aleksandrova, M.; Mandleywala, K.; Nunes, P. R.; Khatun, J.; Kim, O.; Affronti, H.; Chiles, E.; Su, X.; Khiabanian, H.; Wellen, K.; Herranz, D.
10.1101/2023.03.27.534395 — cancer biology — Posted on 2023-03-28
529 Robust phenotyping of highly multiplexed tissue imaging data using pixel-level clustering
Liu, C. C.; Greenwald, N. F.; Kong, A.; McCaffrey, E. F.; Leow, K. X.; Mrdjen, D.; Cannon, B. J.; Rumberger, J. L.; Vara, S. R.; Angelo, M.
10.1101/2022.08.16.504171 — bioinformatics — Posted on 2023-03-28
532 Lineage-specific dynamics of erasure of X-upregulation during inactive-X reactivation
Naik, H.; Chandel, D.; Majumdar, S.; Arava, M.; Baro, R.; BV, H.; Hari, K.; A, P.; Manhas, A.; Jolly, M.; Gayen, S.
10.1101/2020.12.23.424181 — genetics — Posted on 2023-03-28
538 A Conserved Switch Controls Virulence, Sporulation, and Motility in C. difficile
DiCandia, M. A.; Edwards, A. N.; Lee, C. D.; Monteiro, M. P.; Vargas-Cuebas, G. G.; Bagchi, P.; McBride, S. M.
10.1101/2023.03.28.534590 — microbiology — Posted on 2023-03-28
541 Distinct mesoscale cortical dynamics encode search strategies during spatial navigation
Surinach, D.; Rynes, M. L.; Saxena, K.; Ko, E.; Redish, A. D.; Redish, A. D.; Kodandaramaiah, S. B.
10.1101/2023.03.27.534480 — neuroscience — Posted on 2023-03-28
543 Statistical analyses of motion-corrupted MRI relaxometry data
Corbin, N.; Oliveira, R.; Raynaud, Q.; Di Domenicantonio, G.; Draganski, B.; Kherif, F.; Callaghan, M. F.; Lutti, A.
10.1101/2023.03.16.532911 — neuroscience — Posted on 2023-03-28
547 An Unexpected Role of Neutrophils in Clearing Apoptotic Hepatocytes In Vivo
Cao, L.; Ma, L.; Zhao, J.; Wang, X.; Fang, X.; Li, W.; Qi, Y.; Tang, Y.; Liu, J.; Peng, S.; Yang, L.; Zhou, L.; Li, L.; Hu, X.; Ji, Y.; Hou, Y.; Zhao, Y.; Zhang, X.; Zhao, Y.; Zhao, Y.; Wei, Y.; Malik, A.; Saiyin, H.; Xu, J.
10.1101/2023.02.08.527616 — physiology — Posted on 2023-03-28
549 Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data
de Souza, V. B. C.; Jordan, B. T.; Tseng, E.; Nelson, E. A.; Hirschi, K. K.; Sheynkman, G. M.; Robinson, M. D.
10.1101/2022.02.08.479579 — bioinformatics — Posted on 2023-03-28
553 Reduced histone gene copy number disrupts Drosophila Polycomb function
McPherson, J.-M. E.; Grossmann, L. C.; Salzler, H. R.; Armstrong, R. L.; Kwon, E.; Matera, A. G.; McKay, D. J.; Duronio, R. J.
10.1101/2023.03.28.534544 — genetics — Posted on 2023-03-28
555 BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels
Han, D.; Schaffner, S.; Davies, J. P.; Benton, M. L.; Plate, L.; Nordman, J.
10.1101/2023.03.28.534572 — molecular biology — Posted on 2023-03-28
557 The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation
Lim, J. K.; Samiei, A.; Carnie, C. J.; Brinkman, V.; Radiloff, D.; Cran, J.; Leprivier, G.; Sorensen, P. H.
10.1101/2023.03.28.534603 — molecular biology — Posted on 2023-03-28
559 Spatial structure, chemotaxis and quorum sensing shape biomass accumulation in complex systems
Scheidweiler, D.; Bordoloi, A. D.; Sentchilo, V.; Bollani, M.; Engel, P.; de Anna, P.
10.1101/2023.03.28.534616 — microbiology — Posted on 2023-03-28
561 Mutation nsp6 L232F associated with MERS-CoV zoonotic transmission confers higher viral replication in human respiratory tract cultures ex-vivo
So, R. T.; Chu, D. K. W.; Hui, K. P. Y.; Mok, C. K.-P.; Sanyal, S.; Nicholls, J. M.; Ho, J. C. W.; Cheung, M. C.; NG, K. C.; Yeung, H. W.; Chan, M. C. W.; Poon, L. L. M.; Zhao, J.; Peiris, J. S. M.
10.1101/2023.03.27.534490 — microbiology — Posted on 2023-03-28
563 PRC domain-containing proteins modulate FtsZ-based archaeal cell division
Nussbaum, P.; Kureisaite-Ciziene, D.; Bellini, D.; van der Does, C.; Kojic, M.; Taib, N.; Gribaldo, S.; Loose, M.; Loewe, J.; Albers, S.-V.
10.1101/2023.03.28.534543 — microbiology — Posted on 2023-03-28
564 Loss of type VI secretion systems in multi-drug resistant Escherichia coli clones
Cummins, E.; Moran, R.; Snaith, A.; Hall, R.; Connor, C.; Dunn, S.; McNally, A.
10.1101/2023.03.28.534550 — microbiology — Posted on 2023-03-28
565 Synthesis and validation of click-modified of NOD1/2 agonists
Bharadwaj, R.; Anonick, M. V.; Mashayekh, S.; Brown, A.; Wodzanowski, K. A.; Okuda, K.; Silverman, N.; Grimes, C. L.
10.1101/2023.03.28.534546 — immunology — Posted on 2023-03-28
567 Ultrasound neuromodulation of an anti-inflammatory pathway at the spleen produces sustained improvement of experimental pulmonary hypertension
Zafeiropoulos, S.; Ahmed, U.; Mughrabi, I.; Jayaprakash, N.; Chadwick, C.; Daytz, A.; Bekiaridou, A.; Saleknezhad, N.; Atish-Fregoso, Y.; Carroll, K.; Giannakoulas, G.; al-Abed, Y.; Puleo, C.; Nicolls, M. R.; Diamond, B.; Zanos, S.
10.1101/2023.03.28.534567 — neuroscience — Posted on 2023-03-28
568 Distinct sources and behavioral correlates of macaque motor cortical low and high beta
Nougaret, S.; Lopez-Galdo, L.; Caytan, E.; Poitreau, J.; Barthelemy, F. V.; Kilavik, B. E.
10.1101/2023.03.28.534535 — neuroscience — Posted on 2023-03-28
569 Radiosynthesis automation, non-human primate biodistribution and dosimetry of K+ channel tracer 3MeO4AP
Zhou, Y.-P.; Wilks, M. Q.; Dhaynaut, M.; Guehl, N. J.; Moon, S.-H.; El Fakhri, G.; Normandin, M. D.; Brugarolas, P.
10.1101/2023.03.28.534386 — neuroscience — Posted on 2023-03-28
572 CA3 hippocampal synaptic plasticity supports ripple physiology during memory consolidation
El-Oussini, H.; Zhang, C.-L.; Francois, U.; Castelli, C.; Lampin Saint-Amaux, A.; Lepleux, M.; Molle, P.; Velez, L.; Dejean, C.; Lanore, F.; Herry, C.; Choquet, D.; Humeau, Y.
10.1101/2023.03.28.534509 — neuroscience — Posted on 2023-03-28
577 Deep Learning Initialized Compressed Sensing (Deli-CS) in Volumetric Spatio-Temporal Subspace Reconstruction
Iyer, S. S.; Schauman, S. S.; Sandino, C.; Yurt, M.; Cao, X.; Liao, C.; Ruengchaijatuporn, N.; Chatnuntawech, I.; Tong, E.; Setsompop, K.
10.1101/2023.03.28.534431 — neuroscience — Posted on 2023-03-28
578 A visual paired associate learning (vPAL) paradigm to study memory consolidation during sleep
Schmidig, F. J.; Geva-Sagiv, M.; Falach, R.; Yakim, S.; Gat, Y.; Sharon, O.; Fried, I.; Nir, Y.
10.1101/2023.03.28.534494 — neuroscience — Posted on 2023-03-28
580 Stable mammalian serum albumins designed for bacterial expression
Khersonsky, O.; Fleishman, S. J.; Goldsmith, M.; Zaretsky, I.; Hamer-Rogotner, S.; Dym, O.
10.1101/2023.03.28.534334 — biochemistry — Posted on 2023-03-28
581 Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements
Chardon, F. M.; McDiarmid, T. A.; Page, N. F.; Martin, B. K.; Domcke, S.; Regalado, S. G.; Lalanne, J.-B.; Calderon, D.; Starita, L. M.; Sanders, S. J.; Ahituv, N.; Shendure, J.
10.1101/2023.03.28.534017 — genomics — Posted on 2023-03-28
584 Widespread PRC barrel proteins play critical roles in archaeal cell division
Zhao, S.; Makarova, K.; Zheng, W.; Liu, Y.; Zhan, L.; Wan, Q.; Gong, H.; Krupovic, M.; Lutkenhaus, J.; Chen, X.; Koonin, E. V.; Du, S.
10.1101/2023.03.28.534520 — microbiology — Posted on 2023-03-28
585 The Intra-Host Evolutionary Landscape And Pathoadaptation Of Persistent Staphylococcus aureus In Chronic Rhinosinusitis
Houtak, G.; Bouras, G.; Nepal, R.; Shaghayegh, G.; Cooksley, C.; Psaltis, A. J.; Wormald, P.-J.; Vreugde, S.
10.1101/2023.03.28.534496 — microbiology — Posted on 2023-03-28
586 Tau seeding and spreading in vivo is supported by both fibrillar and oligomeric tau
Mate de Gerando, A.; Welikovitch, L. A.; Khasnavis, A.; Commins, C.; Glynn, C.; Perbet, R.; Hyman, B. T.
10.1101/2023.03.28.534418 — neuroscience — Posted on 2023-03-28
587 Substrate reduction therapy in a Drosophila melanogaster model of Sanfilippo syndrome
Tan, S. L.; Hewson, L. J.; Mustaffar, N. F.; He, Q. Q.; Wimmer, N.; Trim, P. J.; King, B. M.; Snel, M. F.; Hemsley, K. M.; Ferro, V.; O'Keefe, L. V.; Lau, A. A.
10.1101/2023.03.27.534462 — neuroscience — Posted on 2023-03-28
588 Hippocampal and amygdala subfield volumes in obsessive-compulsive disorder differ according to medication status.
Ntwatwa, Z.; Lochner, C.; Roos, A.; Sevenoaks, T.; van Honk, J.; Alonso, P.; Batistuzzo, M. C.; Choi, S.; Hoexter, M. Q.; Kim, M.; Kwon, J. S.; Mataix-Cols, D.; Menchon, J. M.; Miguel, E. C.; Nakamae, T.; Phillips, M. L.; Soriano-Mas, C.; Veltman, D.; Groenewold, N. A.; van den Heuvel, O. A.; Stein, D. J.; Ipser, J.
10.1101/2023.03.28.534348 — neuroscience — Posted on 2023-03-28
591 Spatiotemporal transcriptomic map of ischemic brain injury
Zucha, D.; Abaffy, P.; Kirdajova, D.; Jirak, D.; Anderova, M.; Kubista, M.; Valihrach, L.
10.1101/2023.03.28.534553 — neuroscience — Posted on 2023-03-28
593 Therapeutic targeting of ACLY in T-ALL in vivo
da Silva-Diz, V.; Singh, A.; Lancho, O.; Aleksandrova, M.; Mandleywala, K.; Nunes, P. R.; Khatun, J.; Kim, O.; Chiles, E.; Su, X.; Khiabanian, H.; Wellen, K.; Herranz, D.
10.1101/2023.03.27.534395 — cancer biology — Posted on 2023-03-28
594 Replicative stress in gastroesophageal adenocarcinoma is associated with chromosomal instability and sensitivity to DNA damage response inhibitors.
Sahgal, P.; Patil, D. T.; Sztupinszki, Z.; Tisza, V.; Spisak, S.; Huffman, B.; Prosz, A.; Singh, H.; Lazaro, J.-B.; Szallasi, Z.; Cleary, J. M.; Sethi, N. S.
10.1101/2023.03.27.534412 — cancer biology — Posted on 2023-03-28
597 Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitis
Sasaki, M.; Hara, T.; Wang, J. X.; Zhou, Y.; Kennedy, K. V.; Umeweni, N. N.; Alston, M. A.; Spergel, Z. C.; Nakagawa, R.; McMillan, E. A.; Whelan, K. A.; Karakasheva, T. A.; Hamilton, K. E.; Ruffner, M. A.; Muir, A. B.
10.1101/2023.03.27.534387 — cell biology — Posted on 2023-03-28
598 Altered muscle niche contributes to myogenic deficit in the D2-mdx model of severe DMD
Mazala, D. A.; Hindupur, R.; Moon, Y. J.; Shaikh, F.; Gamu, I. H.; Alladi, D.; Panci, G.; Weiss-Gayet, M.; Chazaud, B.; Partridge, T. A.; Novak, J. S.; Jaiswal, J. K.
10.1101/2023.03.27.534413 — pathology — Posted on 2023-03-28
599 EGFR inhibition in lung adenocarcinoma upregulates cell surface expression of the placental antigen ALPP and enhances efficacy of ALPP-ADC therapy
chen, y.; Hong, M. J.; Xu, H.; Vykoukal, J.; Park, S.; Cai, y.; Leon-Letelier, R. A.; Irajizad, E.; Hsiao, F. C.; Dennison, J. B.; Ostrin, E. J.; Fahrmann, J. F.; Katayama, H.; Hanash, S. M.
10.1101/2023.03.27.534173 — cancer biology — Posted on 2023-03-28
600 Energetics and kinetics of membrane permeation of photoresists for bioprinting
Diedrich, L.; Brosz, M.; Abele, T.; Steinke, S.; Grater, F.; Gopfrich, K.; Aponte-Santamaria, C.
10.1101/2023.03.27.534360 — biophysics — Posted on 2023-03-28
601 Quantitative determination of fluorescence labeling implemented in cell cultures
Schirripa Spagnolo, C.; Moscardini, A.; Amodeo, R.; Beltram, F.; Luin, S.
10.1101/2023.03.27.534369 — biophysics — Posted on 2023-03-28
605 TemStaPro: protein thermostability prediction using sequence representations from protein language models
Pudziuvelyte, I.; Olechnovic, K.; Godliauskaite, E.; Sermokas, K.; Urbaitis, T.; Gasiunas, G.; Kazlauskas, D.
10.1101/2023.03.27.534365 — bioinformatics — Posted on 2023-03-28
609 De novo assembly of the black flounder genome. Why do pleuronectiformes have such a small genome size?
Villarreal, F.; Burguener, G. F.; Sosa, E. J.; Stocchi, N.; Somoza, G. M.; Turjanski, A.; Blanco, A.; Vinas, J.; Mechaly, A. S.
10.1101/2023.03.27.534153 — genomics — Posted on 2023-03-28
610 Dynamics of the rice yellow mottle disease in western Burkina Faso: epidemic monitoring, spatio-temporal variation of viral diversity and pathogenicity in a disease hotspot
Billard, E.; Barro, M.; Sereme, D.; Bangratz, M.; Wonni, I.; Koala, M.; Itolou Kassankogno, A.; Hebrard, E.; Thebaud, G.; Brugidou, C.; Poulicard, N.; Tollenaere, C.
10.1101/2023.03.27.534376 — evolutionary biology — Posted on 2023-03-28
611 Planning to revisit: neural activity in refixation precursors
Nikolaev, A. R.; Ehinger, B. V.; Meghanathan, R. N.; van Leeuwen, C.
10.1101/660308 — neuroscience — Posted on 2023-03-28
614 Menstrual cycle associated alteration of vastus lateralis motor unit function
Piasecki, J.; Guo, Y.; Jones, E. J.; Phillips, B. E.; Stashuk, D. W.; Atherton, P. J.; Piasecki, M.
10.1101/2023.03.27.534396 — physiology — Posted on 2023-03-28
616 Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease
D'Oliviera, A.; Dai, X.; Mottaghinia, S.; Geissler, E. P.; Etienne, L.; Zhang, Y.; Mugridge, J. S.
10.1101/2023.02.20.529306 — biochemistry — Posted on 2023-03-28
617 Cortico-thalamo-cortical interactions modulate electrically evoked EEG responses in mice
Claar, L. D.; Rembado, I.; Kuyat, J. R.; Russo, S.; Marks, L. C.; Olsen, S. R.; Koch, C.
10.1101/2022.07.22.501195 — neuroscience — Posted on 2023-03-28
618 NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype
Muela-Zarzuela, I.; Suarez-Rivero, J. M.; Gallardo-Orihuela, A.; Wang, C.; Izawa, K.; de Gregorio-Procopio, M.; Couillin, I.; Ryffel, B.; Kitaura, J.; Sanz, A.; von Zglinicki, T.; Mbalaviele, G.; Cordero, M. D.
10.1101/2023.02.06.527254 — immunology — Posted on 2023-03-28
620 Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study
Itahashi, T.; Yamashita, A.; Takahara, Y.; Yahata, N.; Aoki, Y. Y.; Fujino, J.; Yoshihara, Y.; Nakamura, M.; Aoki, R.; Ohta, H.; Sakai, Y.; Takamura, M.; Ichikawa, N.; Okada, G.; Okada, N.; Kasai, K.; Tanaka, S. C.; Imamizu, H.; Kato, N.; Okamoto, Y.; Takahashi, H.; Kawato, M.; Yamashita, O.; Hashimoto, R.-i.
10.1101/2023.03.26.534053 — neuroscience — Posted on 2023-03-28
622 Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia
Gaspari, S.; Labouebe, G.; Picard, A.; Berney, X. P.; Rodriguez Sanchez-Archidona, A.; Thorens, B.
10.1101/2022.10.21.513159 — physiology — Posted on 2023-03-28
623 Meta-analysis of (single-cell method) benchmarks reveals the need for extensibility and interoperability
Sonrel, A.; Luetge, A.; Soneson, C.; Mallona Gonzalez, I.; Germain, P.-L.; Knyazev, S.; Gilis, J.; Gerber, R.; Seurinck, R.; Paul, D.; Sonder, E.; Crowell, H. L.; Fanaswala, I.; Al Ajami, A.; Heidari, E.; Schmeing, S.; Milosavljevic, S.; Saeys, Y.; Mangul, S.; Robinson, M. D.
10.1101/2022.09.22.508982 — bioinformatics — Posted on 2023-03-28
624 Somatic small-variant calling methods in Illumina DRAGEN™ Secondary Analysis
Scheffler, K.; Catreux, S.; O'Connell, T.; Jo, H.; Jain, V.; Heyns, T.; Yuan, J.; Murray, L.; Han, J.; Mehio, R.
10.1101/2023.03.23.534011 — bioinformatics — Posted on 2023-03-28
626 Leaf metabolic traits reveal hidden dimensions of plant form and function
Walker, T. W. N.; Schrodt, F.; Allard, P.-M.; Defossez, E.; Jassey, V. E.; Schuman, M. C.; Alexander, J. M.; Baines, O.; Baldy, V.; Bardgett, R. D.; Capdevila, P.; Coley, P. D.; van Dam, N. M.; David, B.; Descombes, P.; Endara, M.-J.; Fernandez, C.; Forrister, D.; Gargallo-Garriga, A.; Glauser, G.; Marr, S.; Neumann, S.; Pellissier, L.; Peters, K.; Rasmann, S.; Roessner, U.; Salguero-Gomez, R.; Sardans, J.; Weckwerth, W.; Wolfender, J.-L.; Penuelas, J.
10.1101/2023.03.08.531692 — ecology — Posted on 2023-03-28
628 Huntingtin Interacting Protein-1 expression is regulated via HIF2 axis in Lung Adenocarcinoma
Prasad, P.; Chongtham, J.; Tripathi, S. C.; Ganguly, N. K.; Mittal, S. A.; Srivastava, T.
10.1101/2023.03.27.534427 — cancer biology — Posted on 2023-03-28
631 Foldseek: fast and accurate protein structure search
van Kempen, M.; Kim, S.; Tumescheit, C.; Mirdita, M.; Lee, J.; Gilchrist, C. L. M.; Soeding, J.; Steinegger, M.
10.1101/2022.02.07.479398 — bioinformatics — Posted on 2023-03-28
632 A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence
Hennart, M.; Crestani, C.; Bridel, S.; Armatys, N.; Bremont, S.; Carmi-Leroy, A.; Landier, A.; Passet, V.; Fonteneau, L.; Vaux, S.; Toubiana, J.; Badell-Ocando, E.; Brisse, S.
10.1101/2023.02.20.529124 — microbiology — Posted on 2023-03-28
638 Inducing an oxidized redox-balance improves anti-tumor CD8+ T cell function
Oh, J. H.; Cederberg, R. A.; Bopp, L.; Tanaka, E.; Ser, T.; Niyyati, S.; Patterson, A. E.; Amanat, N.; Dutra, J.; Ye, P.; Clark, M.; Ward-Hartstonge, K.; Archambault, A.-S.; Tsui, J.; Lange, P. F.; Tsai, S.; Verchere, C. B.; Park, Y.; Fabri, M.; Bennewith, K. L.; Geltink, R. I. K.
10.1101/2023.03.27.533229 — immunology — Posted on 2023-03-27
640 Photoprotection is regulated by light-independent CO2 availability
Ruiz-Sola, M. A.; Flori, S.; Yuan, Y.; Villain, G.; Sanz-Luque, E.; Redekop, P.; Tokutsu, R.; Küken, A.; Tsichla, A.; Kepesidis, G.; Allorent, G.; Arend, M.; Iacono, F.; Finazzi, G.; Hippler, M.; Nikoloski, Z.; Minagawa, J.; Grossman, A. R.; Petroutsos, D.
10.1101/2021.10.23.465040 — plant biology — Posted on 2023-03-27
642 Huntingtin Interacting Protein-1 expression is regulated via HIF2 axis in Lung Adenocarcinoma
Prasad, P.; Chongtham, J.; Tripathi, S. C.; Ganguly, N. K.; Mittal, S. A.; Srivastava, T.
10.1101/2023.03.27.534427 — cancer biology — Posted on 2023-03-27
645 JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations
Chandrasekaran, S. N.; Ackerman, J.; Alix, E.; Ando, D. M.; Arevalo, J.; Bennion, M.; Boisseau, N.; Borowa, A.; Boyd, J. D.; Brino, L.; Byrne, P. J.; Ceulemans, H.; Ch'ng, C.; Cimini, B. A.; Clevert, D.-A.; Deflaux, N.; Doench, J. G.; Dorval, T.; Doyonnas, R.; Dragone, V.; Engkvist, O.; Faloon, P. W.; Fritchman, B.; Fuchs, F.; Garg, S.; Gilbert, T. J.; Glazer, D.; Gnutt, D.; Goodale, A.; Grignard, J.; Guenther, J.; Han, Y.; Hanifehlou, Z.; Hariharan, S.; Hernandez, D.; Horman, S. R.; Hormel, G.; Huntley, M.; Icke, I.; Iida, M.; Jacob, C. B.; Jaensch, S.; Khetan, J.; Kost-Alimova, M.; Krawiec,
10.1101/2023.03.23.534023 — bioinformatics — Posted on 2023-03-27
649 Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations
Emfinger, C.; Clark, L. E.; Yandell, B. S.; Schueler, K. L.; Simonett, S.; Stapleton, D. S.; Mitok, K.; Merrins, M. J.; Keller, M. P.; Attie, A. D.
10.1101/2022.11.26.517741 — biochemistry — Posted on 2023-03-27
651 Placental Cell Conditioned Media Modifies Hematopoietic Stem Cell Transcriptome In Vitro
Harris, S. M.; Su, A. L.; Dou, J.; Loch-Caruso, R.; Elkin, E. R.; Jaber, S.; Bakulski, K.
10.1101/2023.03.27.534393 — developmental biology — Posted on 2023-03-27
652 Cooperative Motility, Force Generation and Mechanosensing in a Foraging Non-Photosynthetic Diatom
Zheng, P.; Kumadaki, K.; Quek, C.; Lim, Z. H.; Ashenafi, Y.; Yip, Z. T.; Newby, J.; Alverson, A. J.; Jedd, G.
10.1101/2023.03.27.533254 — cell biology — Posted on 2023-03-27
654 Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans
Hahn, A.; Hung, G. C. C.; Ahier, A.; Forde, B. M.; Dai, C.-Y.; Lee, R. S. Y.; Campbell, D.; Onraet, T.; Kirmes, I.; Zuryn, S.
10.1101/2023.03.27.534335 — molecular biology — Posted on 2023-03-27
655 Incidences of Helicobacter infection in pigs and tracing occupational hazard in pig farmers
Pegu, S. R. R.; Rajkhowa, S.; Das, P. J.; Sonowal, J.; Sengar, G. S.; Deb, R.; Choudhury, M.; Deka, N.; Paul, S.; Doley, J.; Sarma, D. K.; Das, S.; Mohon, N. H.; Thomas, R.; Gupta, V. K.
10.1101/2023.03.27.534128 — microbiology — Posted on 2023-03-27
657 Neutrophil efferocytosis reprograms mitochondrial metabolism to switch alveolar macrophages to a pro-resolution phenotype at the cost of bacterial control
Better, J.; Wetstein, M.; Estiri, M.; Malainou, C.; Ferrero, M.; Langelage, M.; Kuznetsova, I.; Vazquez-Armendariz, I.; Kimmig, L.; Mansouri, S.; Savai, R.; Wilhelm, J.; Alexopoulos, I.; Sommer, N.; Herold, S.; Matt, U.
10.1101/2023.03.07.528464 — immunology — Posted on 2023-03-27
660 Scalable Apparatus to Measure Posture and Locomotion (SAMPL): a high-throughput solution to study unconstrained vertical behavior in small animals
Zhu, Y.; Auer, F.; Gelnaw, H.; Davis, S. N.; Hamling, K. R.; May, C. E.; Ahamed, H.; Ringstad, N.; Nagel, K. I.; Schoppik, D.
10.1101/2023.01.07.523102 — neuroscience — Posted on 2023-03-27
661 Cestode larvae excite host neuronal circuits via glutamatergic signaling.
de Lange, A.; Tomes, H.; Selfe, J. S.; Prodjinotho, U. F.; Verhoog, M. B.; Mahanty, S.; Smith, K.; Horsnell, W.; Sikasunge, C.; da Costa, C. P.; Raimondo, J. V.
10.1101/859009 — neuroscience — Posted on 2023-03-27
662 PhysiBoSS 2.0: a sustainable integration of stochastic Boolean and agent-based modelling frameworks
Ponce-de-Leon, M.; Montagud, A.; Noel, V.; Pradas, G.; Meert, A.; Barillot, E.; Calzone, L.; Valencia, A.
10.1101/2022.01.06.468363 — systems biology — Posted on 2023-03-27
663 Novel RNA m6A methyltransferase METTL16 inhibitors
Selberg, S.; Ivanova, L.; Kotli, M.; Herodes, K.; Blokhina, D.; Kankuri, E.; Seli, N.; Ilves, I.; Teino, I.; Saarma, M.; Karelson, M.
10.1101/2023.03.27.534333 — pharmacology and toxicology — Posted on 2023-03-27
664 APOL1 kidney risk variants in glomerular diseases modeled in transgenic mice
Yoshida, T.; Latt, K. Z.; Santo, B. A.; Shrivastav, S.; Zhao, Y.; Fenaroli, P.; Chung, J.-Y.; Hewitt, S. M.; Tutino, V. M.; Sarder, P.; Rosenberg, A. Z.; Winkler, C. A.; Kopp, J. B.
10.1101/2023.03.27.534273 — pathology — Posted on 2023-03-27
666 ATP citrate lyase is an essential player of the metabolic rewiring induced by PTEN loss during T-ALL development.
Andrieu, G.; Hypolite, G.; Balducci, E.; Costa, C.; Verhoeyen, E.; Nemazanyy, I.; Panasyuk, G.; Wellen, K.; Macintyre, E.; Asnafi, V.; Tesio, M.
10.1101/2023.03.27.534353 — cancer biology — Posted on 2023-03-27
669 Phase Separation and Ageing of Glycine-Rich Protein from Tick Adhesive
Ganar, K. A.; Turbina, P.; Nandy, M.; Chen, C.; Suylen, D.; van der Beelen, S.; Pascoe, E. L.; Koenraadt, C. J. M.; Dijkgraaf, I.; Deshpande, S.
10.1101/2023.03.27.534361 — biochemistry — Posted on 2023-03-27
671 A divergent protein kinase A in the human pathogen Leishmania is associated with cell cortex microtubules and controls cell shape
Fischer-Weinberger, R.; Bachmaier, S.; Ober, V.; Githure, G. B.; Dandugudumuoa, R.; Phan, I. Q.; Almoznino, M.; Polatoglou, E.; Tsigankove, P.; Nitzan Koren, R.; Myler, P. J.; Boshart, M. J.; Zilberstein, D.
10.1101/2021.04.24.440790 — cell biology — Posted on 2023-03-27
672 Dynamics of the DYNLL1/MRE11 complex regulates DNA end resection and recruitment of the Shieldin complex to DSBs
Zhou, R.; Swift, M. L.; Syed, A.; Huang, K.; Moreau, L.; Tainer, J. A.; Konstantinopoulos, P. A.; D'Andrea, A. D.; He, Y. J.; Chowdhury, D.
10.1101/2023.03.27.534416 — molecular biology — Posted on 2023-03-27
676 FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates
Barghouth, P. G.; Melemenidis, S.; Montay-Gruel, P.; Ollivier, J.; Viswanathan, V.; Jorge, P. G.; Soto, L.; Lau, B. C.; Sadeghi, C.; Edlabadkar, A.; Manjappa, R.; Wang, J.; Le Bouteiller, M.; Surucu, M.; Yu, A.; Bush, K.; Skinner, L.; Maxim, P. G.; Loo, B. W.; Limoli, C. L.; Vozenin, M.-C.; Frock, R. L.
10.1101/2023.03.27.534408 — molecular biology — Posted on 2023-03-27
678 Enhanced niche colonisation and competition during bacterial adaptation to a fungus
Richter, A.; Blei, F.; Hu, G.; Schwitalla, J. W.; Lozano-Andrade, C. N.; Jarmusch, S. A.; Wibowo, M.; Kjeldgaard, B.; Surabhi, S.; Jautzus, T.; Phippen, C. B. W.; Tyc, O.; Arentshorst, M.; Wang, Y.; Garbeva, P.; Larsen, T. O.; Ram, A. F. J.; van den Hondel, C. A. M.; Maroti, G.; Kovacs, A. T.
10.1101/2023.03.27.534400 — microbiology — Posted on 2023-03-27
679 SARS-CoV-2 accessory proteins involvement in inflammatory and profibrotic processes through IL11 signaling
Dies, B.; de Lucas-Rius, A.; Mendoza, L.; Garcia, T.; Fernandez, R.; Suarez, J. M.; Milhano, F.; Corrales, F.; Redondo, N.; Pedrucci, F.; Zaldivar, S.; Jimenez, M. A.; Montoya, M.; Garrido, J. J.
10.1101/2023.03.27.534381 — immunology — Posted on 2023-03-27
681 A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Carhart-Harris, R. L.; Williams, G. B.; Craig, M. M.; Finoia, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2020.11.25.398081 — neuroscience — Posted on 2023-03-27
683 Sex differences in the role of parabrachial in nociception and pain in awake mice
Smith, J.; Ji, Y.; Lorsung, R.; Breault, M.; Koenig, J.; Cramer, N. P.; Masri, R.; Keller, A.
10.1101/2023.03.22.533230 — neuroscience — Posted on 2023-03-27
685 Anticancer efficacy of KRASG12C inhibitors is potentiated by PAK4 inhibitor KPT9274 in preclinical models of KRASG12C mutant pancreatic and lung cancers
Khan, H. Y.; Nagasaka, M.; Aboukameel, A.; Alkhalili, O.; Uddin, M. H.; Bannoura, S.; Mzannar, Y.; Ibrahim, A.; Beal, E.; Tobon, M.; Kim, S.; Beydoun, R.; Baloglu, E.; Senapedis, W.; Elrayes, B.; Philip, P. A.; Mohammad, R. M.; Shields, A. F.; Al-Hallak, M. N.; Azmi, A. S.
10.1101/2023.03.27.534309 — cancer biology — Posted on 2023-03-27
689 Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons
Chou, C.-C.; Vest, R.; Prado, M. A.; Wilson-Grady, J.; Paulo, J. A.; Shibuya, Y.; Moran-Losada, P.; Lee, T.-T.; Luo, J.; Gygi, S. P.; Kelly, J. W.; Finley, D.; Wernig, M.; Wyss-Coray, T.; Frydman, J.
10.1101/2023.03.27.534444 — cell biology — Posted on 2023-03-27
696 A single-cell atlas of the free-living miracidium larva of Schistosoma mansoni
Rawlinson, K. A.; Attenborough, T.; Soria, C. L. D.; Ambridge, K.; Sankaranarayanan, G.; Graham, J.; Doyle, S. R.; Rinaldi, G.; Berriman, M.
10.1101/2023.03.27.533868 — genomics — Posted on 2023-03-27
700 A rationally designed inactivated Salmonella Typhimurium vaccine induces strong and long-lasting immune responses in pigs
Lentsch, V.; Aslani, S.; Echtermann, T.; Preet, S.; Cappio Barazzone, E.; Hoces, D.; Moresi, C.; Kuemmerlen, D.; Slack, E.
10.1101/2023.03.27.534319 — immunology — Posted on 2023-03-27
701 Structural modification of naturally-occurring phenolics as a strategy for developing cytotoxic molecules towards cancer cells
Olim, P. A.; Pereira, R. B.; Fernandes, M. J. G.; Natal, C. M.; Coelho, J. R. A.; Fortes, A. G.; Goncalves, M. S. T.; Pereira, D. M.
10.1101/2023.03.26.534257 — pharmacology and toxicology — Posted on 2023-03-27
702 PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma
Boudra, R.; Patenall, B. L.; King, S.; Wang, D.; Best, S. A.; Ko, J. Y.; Xu, S.; Padilla, M. G.; Schmults, C. D.; Barthel, S. R.; Lian, C. G.; Ramsey, M. R.
10.1101/2023.03.27.533164 — cancer biology — Posted on 2023-03-27
706 Fortuitous in vitro compound degradation produces a tractable hit against Mycobacterium tuberculosis dethiobiotin synthetase: a cautionary tale of what goes in, does not always come out
Salaemae, W.; Thompson, A. P.; Gaiser, B. I.; Lee, K. J.; Huxley, M. T.; Sumby, C. J.; Polyak, S. W.; Abell, A. D.; Bruning, J. B.; Wegener, K. L.
10.1101/2023.03.26.531482 — biochemistry — Posted on 2023-03-27
711 RFIDeep: Unfolding the Potential of Deep Learning forRadio-Frequency Identification
Bardon, G.; Cristofari, R.; Winterl, A.; Barracho, T.; Benoiste, M.; Ceresa, C.; Chatelain, N.; Courtecuisse, J.; Fernandes, F. A. N.; Gauthier-Clerc, M.; Gendner, J.-P.; Handrich, Y.; Houstin, A.; Krellenstein, A.; Lecomte, N.; Salmon, C.-E.; Trucchi, E.; Vallas, B.; Wong, E. M.; Zitterbart, D. P.; Le Bohec, C.
10.1101/2023.03.25.534127 — ecology — Posted on 2023-03-27
712 Environmental DNA of aquatic macrophytes: the potential for reconstructing past and present vegetation and environments
Reveret, A.; Rijal, D. P.; Heintzman, P. D.; Brown, A. G.; Stoof-Leichsenring, K. R.; Alsos, I. G.
10.1101/2023.03.27.533457 — ecology — Posted on 2023-03-27
713 A network of CD163+ macrophages monitors enhanced permeability at the blood-dorsal root ganglion barrier
Lund, H.; Hunt, M.; Kurtovic, Z.; Sandor, K.; Fereydouni, N.; Julien, A.; Goeritz, C.; Han, J.; Zhu, K.; Harris, R. A.; Lampa, J.; Haglund, L.; Yaksh, T. L.; Svensson, C. I.
10.1101/2023.03.27.534318 — immunology — Posted on 2023-03-27
714 Distinct Myeloid Derived Suppressor Cell Populations Promote Tumor Aggression in Glioblastoma
Jackson, C.; Cherry, C.; Bom, S.; Dykema, A.; Thompson, E.; Zheng, M.; Ji, Z.; Hou, W.; Li, R.; Zhang, H.; Choi, J.; Rodriguez, F.; Weingart, J.; Yegnasubramanian, S.; Lim, M.; Bettegowda, C.; Powell, J.; Eliesseff, J.; Ji, H.; Pardoll, D.
10.1101/2023.03.26.534192 — immunology — Posted on 2023-03-27
717 Designer grass pea for transgene-free minimal neurotoxin-containing seeds with CRISPR-Cas9
Saha, T.; Shee, R.; Sahid, S.; Shee, D.; Roy, C.; Sharma, R.; Pandey, A.; Paul, S.; Datta, R.
10.1101/2023.03.26.534271 — plant biology — Posted on 2023-03-27
718 Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia
Malyukova, A.; Lahnalampi, M.; Falques, T.; Polonen, P.; Sipola, M.; Mehtonen, J.; Teppo, S.; Viiliainen, J.; Lohi, O.; Hagstrom, A.; Heinaniemi, M.; Sangfelt, O.
10.1101/2023.03.27.534308 — cancer biology — Posted on 2023-03-27
725 The regulation of methylation on the Z chromosome and the identification of multiple novel Male Hyper-Methylated regions in the chicken
Hoglund, A.; Henriksen, R.; Churcher, A. M.; Guerrero-Bosagna, C. G.; Martinez-Barrio, A.; Johnsson, M.; Jensen, P.; Wright, D.
10.1101/2023.03.27.534313 — evolutionary biology — Posted on 2023-03-27
727 Drivers of species knowledge across the Tree of Life
Mammola, S.; Adamo, M.; Antic, D.; Calevo, J.; Cancellario, T.; Cardoso, P.; Chamberlain, D.; Chialva, M.; Durucan, F.; Fontaneto, D.; Goncalves, D.; Martinez, A.; Santini, L.; Rubio-Lopez, I.; Sousa, R.; Villegas-Rios, D.; Verdes, A.; Correia, R. A.
10.1101/2023.03.27.534304 — ecology — Posted on 2023-03-27
730 Chromosomal Duplications of MurZ (MurA2) or MurA (MurA1), Amino Acid Substitutions in MurZ (MurA2), and Absence of KhpAB Obviate the Requirement for Protein Phosphorylation in Streptococcus pneumoniae D39
Tsui, H.-C. T.; Joseph, M.; Zheng, J. J.; Perez, A. J.; Manzoor, I.; Rued, B. E.; Richardson, J. D.; Branny, P.; Doubravova, L.; Massidda, O.; Winkler, M. E.
10.1101/2023.03.26.534294 — microbiology — Posted on 2023-03-27
732 Shedding light on human olfaction: electrophysiological recordings from sensory neurons in acute slices of olfactory epithelium
Hernandez-Clavijo, A.; Sanchez-Trivino, C. A.; Guarneri, G.; Ricci, C.; Mantilla-Esparza, F. A.; Gonzalez-Velandia, K. Y.; Boscolo-Rizzo, P.; Toffanelli, M.; Bonini, P.; Dibattista, M.; Tirelli, G.; Menini, A.
10.1101/2023.03.27.534398 — neuroscience — Posted on 2023-03-27
738 Development of Drosophila as a metazoan model to study inorganic polyphosphate biology
Sarkar, S.; Sharma, H.; Ladke, J. S.; Raran-Kurussi, S.; Bhandari, R.; Jaiswal, M.
10.1101/2023.03.26.534266 — cell biology — Posted on 2023-03-27
739 The mitotic surveillance pathway requires PLK1-dependent 53BP1 displacement from kinetochores
Burigotto, M.; Vigorito, V.; Mattivi, A.; Gliech, C.; Ghetti, S.; Bisio, A.; Lolli, G.; Holland, A. J.; Fava, L. L.
10.1101/2023.03.27.534346 — cell biology — Posted on 2023-03-27
740 Cooperative Motility, Force Generation and Mechanosensing in a Foraging Non-Photosynthetic Diatom
Zheng, P.; Kumadaki, K.; Quek, C.; Lim, Z. H.; Ashenafi, Y.; Yip, Z. T.; Newby, J.; Alverson, A. J.; Jedd, G.
10.1101/2023.03.27.533254 — cell biology — Posted on 2023-03-27
743 Unpacking the functional heterogeneity of the Emotional Face Matching Task: a normative modelling approach
Savage, H. S.; Mulders, P. C. R.; van Eijndhoven, P. F. P.; van Oort, J.; Tendolkar, I.; Vrijsen, J. N.; Beckmann, C. F.; Marquand, A. F.
10.1101/2023.03.27.534351 — neuroscience — Posted on 2023-03-27
744 Subsets of cortico-cortical evoked potentials propagate as traveling waves
Campbell, J. M.; Davis, T. S.; Nesterovich Anderson, D.; Arain, A.; Inman, C. S.; Smith, E. H.; Rolston, J. D.
10.1101/2023.03.27.534002 — neuroscience — Posted on 2023-03-27
745 Discrimination of finger movements by magnetomyography with optically pumped magnetometers
Greco, A.; Baek, S.; Middelmann, T.; Mehring, C.; Braun, C.; Marquetand, J.; Siegel, M.
10.1101/2023.03.27.534368 — neuroscience — Posted on 2023-03-27
747 Axis convergence in C. elegans embryos
Bhatnagar, A.; Nestler, M.; Gross, P.; Kramar, M.; Leaver, M.; Voigt, A.; Grill, S. W.
10.1101/2023.03.27.534329 — biophysics — Posted on 2023-03-27
749 One-step generation of auxin-inducible degron cells with high-efficiency homozygous tagging
Li, S.; Wang, Y.; Stoel, M. v. d.; Zhou, X.; Madhusudan, S.; Kanerva, K.; Nguyen, V. D.; Eskici, N.; Olkkonen, V. M.; Zhou, Y.; Raivio, T.; Ikonen, E.
10.1101/2023.03.26.534268 — cell biology — Posted on 2023-03-27
750 Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
Meineke, B.; Heimgärtner, J.; Caridha, R.; Block, M.; Kimler, K. J.; Pires, M. F.; Landreh, M.; Elsässer, S. J.
10.1101/2023.03.26.534279 — cell biology — Posted on 2023-03-27
751 β-actin is essential for structural integrity and physiological function of the retina
Vedula, P.; Fina, M. E.; Bell, B. A.; Nikonov, S. S.; Kashina, A.; Dong, D. W.
10.1101/2023.03.27.534392 — cell biology — Posted on 2023-03-27
752 The influence of inter-regional delays in generating large-scale brain networks of phase synchronization
Williams, N.; Ojanpera, A.; Siebenhuhner, F.; Toselli, B.; Palva, S.; Arnulfo, G.; Kaski, S.; Palva, J. M.
10.1101/2023.03.27.534336 — neuroscience — Posted on 2023-03-27
754 Integration of recognition, episodic, and associative memories during complex human behavior
Xiao, Y.; Sanchez Lopez, P.; Wu, R.; Wei, P.-H.; Shan, Y.-Z.; Weisholtz, D.; Cosgrove, W. R.; Madsen, J. R.; Stone, S.; Zhao, G.-G.; Kreiman, G.
10.1101/2023.03.27.534384 — neuroscience — Posted on 2023-03-27
758 Amoeba Predation of Cryptococcus: A Quantitative and Population Genomic Evaluation of the Accidental Pathogen Hypothesis
Sauters, T. J. C.; Roth, C.; Murray, D.; Sun, S.; Floyd-Averette, A. J. C.; Onyishi, C. U.; May, R. C.; Heitman, J.; Magwene, P. M.
10.1101/2022.12.08.519367 — genomics — Posted on 2023-03-27
759 Novel Herpesvirus Transcripts with Putative Regulatory Roles in DNA Replication and Global Transcription
Torma, G.; Tombacz, D.; Almsarrhad, I. A.; Csabai, Z.; Nagy, G. A.; Kakuk, B.; Gulyas, G.; McKenzie Spires, L.; Gupta, I.; Fulop, A.; Dormo, A.; Prazsak, I.; Mizik, M.; Dani, V. E.; Csanyi, V.; Zadori, Z.; Toth, Z.; Boldogkoi, Z.
10.1101/2023.03.25.534217 — molecular biology — Posted on 2023-03-27
760 A phenotypically robust model of Spinal and Bulbar Muscular Atrophy in Drosophila
Richardson, K.; Sengupta, M.; Sujkowski, A.; Libohova, K.; Harris, A. C.; Wessells, R.; Merry, D. E.; Todi, S. V.
10.1101/2023.03.25.534140 — neuroscience — Posted on 2023-03-27
765 3D single-cell shape analysis using geometric deep learning
De Vries, M.; Dent, L. G.; Curry, N.; Rowe-Brown, L.; Bousgouni, V.; Tyson, A. L.; Dunsby, C.; Bakal, C.
10.1101/2022.06.17.496550 — bioinformatics — Posted on 2023-03-27
766 Discovering genomic regions associated with the phenotypic differentiation of European local pig breeds
Poklukar, K.; Mestre, C.; Skrlep, M.; Candek-Potokar, M.; Ovilo, C.; Fontanesi, L.; Riquet, J.; Bovo, S.; Schiavo, G.; Ribani, A.; Munoz, M.; Bozzi, R.; Charneca, R.; Quintanilla, R.; Kusec, G.; Mercat, M.-J.; Zimmer, C.; Razmaite, V.; Araujo, J. P.; Radovic, C.; Karolyi, D.; Servin, B.
10.1101/2022.02.22.481248 — genetics — Posted on 2023-03-27
767 Utilizing multi-objective decision support tools for protected area selection
Voskamp, A.; Fritz, S. A.; Koecke, V.; Biber, M.; Nogueira-Brockmeyer, T.; Bertzky, B.; Forrest, M.; Goldstein, A.; Henderson, S.; Hickler, T.; Hof, C.; Kastner, T.; Lang, S.; Manning, P.; Mascia, M. B.; McFadden, I. R.; Niamir, A.; Noon, M.; O'Donell, B.; Opel, M.; Schwede, G.; West, P.; Schenck, C.; Boehning-Gaese, K.
10.1101/2022.02.15.480531 — ecology — Posted on 2023-03-27
770 Phased chromosome-scale genome assembly of an asexual, allopolyploid root-knot nematode reveals complex subgenomic structure
Winter, M. R.; Taranto, A. P.; Yimer, H. Z.; Coomer Blundell, A.; Siddique, S.; Williamson, V. M.; Lunt, D. H.
10.1101/2023.03.20.533402 — genomics — Posted on 2023-03-27
771 Dimeric G-quadruplex motifs-induced NFRs determine strong replication origins in vertebrates
Poulet-Benedetti, J.; Tonnerre-Doncarli, C.; Valton, A.-L.; Laurent, M.; Gerard, M.; Barinova, N.; Parisis, N.; Massip, F.; Picard, F.; Prioleau, M.-N.
10.1101/2022.08.17.504255 — genomics — Posted on 2023-03-27
775 Cell layer-specific expression of the homeotic MADS-box transcription factor PhDEF contributes to modular petunia petal morphogenesis
Chopy, M.; Cavallini-Speisser, Q.; Chambrier, P.; Morel, P.; Just, J.; Hugouvieux, V.; Rodrigues Bento, S.; Zubieta, C.; Vandenbussche, M.; Monniaux, M.
10.1101/2021.04.03.438311 — plant biology — Posted on 2023-03-27
776 Multicellular dynamics on structured surfaces: Stress concentration is a key to controlling complex microtissue morphology on engineered scaffolds
Matsuzawa, R.; Matsuo, A.; Fukamachi, S.; Shimada, S.; Takeuchi, M.; Nishina, T.; Kollmannsberger, P.; Sudo, R.; Okuda, S.; Yamashita, T.
10.1101/2023.03.06.530721 — biophysics — Posted on 2023-03-27
778 Novel emm4 lineage associated with an upsurge in invasive group A streptococcal disease in the Netherlands, 2022
van der Putten, B. C.; Bril-Keijzers, W. C.; Rumke, L. W.; Vestjens, S. M. T.; Koster, L. A.; Willemsen, M.; van Houten, M. A.; Rots, N. Y.; Vlaminckx, B. J. M.; de Gier, B.; van Sorge, N. M.
10.1101/2022.12.31.522331 — microbiology — Posted on 2023-03-27
780 Disorganization of basement membrane zone architecture causes impaired melanocyte inhabitation in vitiligo
Yang, F.; Yang, L.; Kuroda, Y.; Lai, S.; Takahashi, Y.; Sayo, T.; Namiki, T.; Nakajima, K.; Sano, S.; Inoue, S.; Tsuruta, D.; Katayama, I.
10.1101/2022.12.18.520911 — pathology — Posted on 2023-03-27
782 Evolution of a Functionally Intact but Antigenically Distinct DENV Fusion Loop
Meganck, R. M.; Zhu, D.; Dong, S.; Snoderly-Foster, L. J.; Dalben, Y. R.; Thiono, D. J.; White, L. J.; DeSilva, A. M.; Baric, R.; Tse, L. V.
10.1101/2023.03.22.533803 — microbiology — Posted on 2023-03-27
783 Partial or complete loss of norepinephrine differentially alters contextual fear and catecholamine release dynamics in hippocampal CA1
Wilson, L. R.; Plummer, N. W.; Evsyukova, I. Y.; Patino, D.; Stewart, C. L.; Smith, K. G.; Fry, S. A.; Deal, A. L.; Kilonzo, V. W.; Sciolino, N. R.; Cushman, J. D.; jensen, p.
10.1101/2023.03.26.534277 — neuroscience — Posted on 2023-03-27
787 A multi-omics strategy for the study of microbial metabolism: application to the human skin's microbiome
Nothias, L.-F.; Schmid, R.; Garlet, A.; Cameron, H.; Leoty-Okombi, S.; Andre-Frei, V.; Fuchs, R.; Dorrestein, P.; Ternes, P.
10.1101/2023.03.26.532286 — systems biology — Posted on 2023-03-26
795 A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells
Ahmed-Seghir, S.; Jalan, M.; Grimsley, H. E.; Sharma, A.; Twayana, S.; Kosiyatrakul, S. T.; Thompson, C.; Schildkraut, C. L.; Powell, S. N.
10.1101/2023.03.26.534293 — molecular biology — Posted on 2023-03-26
797 An essential role for miR-15/16 in Treg suppression and restriction of proliferation
Johansson, K.; Gagnon, J. D.; Zhou, S.; Fassett, M. S.; Schroeder, A. W.; Kageyama, R.; Bautista, R. A.; Pham, H.; Woodruff, P. G.; Ansel, K. M.
10.1101/2023.03.26.533356 — molecular biology — Posted on 2023-03-26
798 SERODIAGNOSIS OF SALMONELLA INFECTION: USING A LOGISTIC REGRESSION MODEL.
NDAKO, J. A.; Owolabi, I. J.; Junaid, S. A.; Dojumo, V. T.; Ndako, C. J.; Abiodun, O. E.; Omoniyi, R. M.; Bello, S. O.
10.1101/2023.03.26.534120 — microbiology — Posted on 2023-03-26
799 Genomic dissection of endemic carbapenem resistance: metallo-beta-lactamase gene dissemination through clonal, plasmid and integron transfer pathways
Macesic, N.; Hawkey, J.; Vezina, B.; Wisniewski, J. A.; Cottingham, H.; Blakeway, L. V.; Harshegyi, T.; Pragastis, K.; Badoordeen, G. Z.; Dennison, A.; Spelman, D. W.; Jenney, A. W. J.; Peleg, A. Y.
10.1101/2023.03.25.534241 — microbiology — Posted on 2023-03-26
800 Cultivation of SAR202 Bacteria from the Ocean
Lim, Y.; Seo, J.-H.; Giovannoni, S. J.; Kang, I.; Cho, J.-C.
10.1101/2023.03.25.534242 — microbiology — Posted on 2023-03-26
803 Sulfur disproportionating microbial communities in a dynamic, microoxic-sulfidic karst system
Aronson, H. S.; Clark, C. E.; LaRowe, D. E.; Amend, J. P.; Polerecky, L.; Macalady, J. L.
10.1101/2023.03.26.534238 — microbiology — Posted on 2023-03-26
804 Human USP18 protects diverse cancer lineages from Type I Interferon independently of its canonical catalytic function
Jove, V.; Wheeler, H.; Lee, C. W.; Healy, D. R.; Levine, K.; Ralph, E. C.; Yang, B.; Giddabasappa, A.; Loria, P.; Yamaguchi, M.; Casimiro-Garcia, A.; Kessler, B. M.; Pinto-Fernandez, A.; Frattini, V.; Wang, F.; Wes, P. D.
10.1101/2023.03.23.533924 — cancer biology — Posted on 2023-03-26
805 Loss of tristetraprolin activates NF-κB induced phenotypic plasticity and primes transition to lethal prostate cancer
Morel, K. L.; Hamid, A. A.; Falcon, B. G.; Singh, J. N.; Linder, S.; Bergman, A. M.; van der Poel, H. G.; Hofland, I.; Bekers, E. M.; Trostel, S.; Wilkinson, S.; Ku, A. T.; Burkhart, D. L.; Kim, M.; Kim, J.; Plummer, J. T.; You, S.; Sowalsky, A. G.; Zwart, W.; Sweeney, C. J.; Ellis, L.
10.1101/2022.08.05.500896 — cancer biology — Posted on 2023-03-26
809 Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents
Stockwell, S. R.; Scott, D. E.; Fischer, G.; Guarino, E.; Rooney, T. P. C.; Fang, T.-S.; Moschetti, T.; Srinivasan, R.; Alza, E.; Asteian, A.; Dagostin, C.; Alcaide, A.; Rocaboy, M.; Blaszczyk, B.; Higueruelo, A.; Wang, X.; Rossmann, M.; Perrior, T. R.; Blundell, T. L.; Spring, D. R.; McKenzie, G.; Abell, C.; Skidmore, J.; Hyvönen, M.; Venkitaraman, A. R.
10.1101/2023.03.22.533679 — biochemistry — Posted on 2023-03-26
810 Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock
Tariq, D.; Maurici, N.; Bartholomai, B.; Chandrasekaran, S.; Dunlap, J. C.; Bah, A.; CRANE, B. R.
10.1101/2022.11.03.515097 — biochemistry — Posted on 2023-03-26
815 Integrated Drivers of Basal and Acute Immunity in Diverse Human Populations
Souquette, A.; Allen, E. K.; Oshansky, C. M.; Tang, L.; Wong, S.-s.; Jeevan, T.; Shi, L.; Pounds, S.; Elias, G.; Kuan, G.; Balmaseda, A.; Zapata, R.; Shaw-Saliba, K.; Van Damme, P.; Van Tendeloo, V.; Dib, J. C.; Ogunjimi, B.; Webby, R.; Schultz-Cherry, S.; Pekosz, A.; Rothman, R.; Gordon, A.; Thomas, P. G.
10.1101/2023.03.25.534227 — immunology — Posted on 2023-03-26
817 Visual stimuli modulate local field potentials but drive no high-frequency activity in human auditory cortex
Ahveninen, J.; Lee, H.-J.; Yu, H.-Y.; Lee, C.-C.; Chou, C.-C.; Ahlfors, S. P.; Kuo, W.-J.; Jääskeläinen, I. P.; Lin, F.-H.
10.1101/2022.07.18.500417 — neuroscience — Posted on 2023-03-26
820 Metabolic impact of trans 10, cis 12-conjugated linoleic acid on pai transgenic mice
Rao, Y.; Li, S. L.; Li, M. J.; Wang, B. Z.; Wang, Y. Y.; Liang, L. W.; Yu, S.; Liu, Z. P.; Cui, S.; GOU, K. M.
10.1101/2023.01.31.526123 — physiology — Posted on 2023-03-26
823 Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons
Virga, D. M.; Hamilton, S.; Osei, B.; Morgan, A.; Zamponi, E.; Park, N. J.; Hewitt, V. L.; Zhang, D.; Gonzalez, K. C.; Bloss, E.; Polleux, F.; Lewis, T. L.
10.1101/2023.03.25.534233 — cell biology — Posted on 2023-03-26
825 Oxidation-sensitive cysteines drive IL-38 amyloid formation
Diaz-Barreiro, A.; Cereghetti, G.; Tonacini, J.; Talabot-Ayer, D.; Kieffer-Jaquinod, S.; Huard, A.; Swale, C.; Coute, Y.; Peter, M.; Frances-Monerris, A.; Palmer, G.
10.1101/2023.03.26.534252 — cell biology — Posted on 2023-03-26
826 Cell-type-specificity of isoform diversity in the developing human neocortex informs mechanisms of neurodevelopmental disorders
Patowary, A.; Zhang, P.; Jops, C.; Vuong, C.; Ge, X.; Hou, K.; Kim, M.; Gong, N.; Margolis, M.; Vo, D.; Wang, X.; Liu, C.; Pasaniuc, B.; Li, J. J.; Gandal, M.; de la Torre-Ubieta, L.
10.1101/2023.03.25.534016 — genomics — Posted on 2023-03-26
828 Taxonomic distribution of metabolic functions underpins nutrient cycling in Trichodesmium consortia
Koedooder, C.; Zhang, F.; Wang, S.; Haley, S. T.; Tolic, N.; Nicora, C. D.; Glavina del Rio, T.; Basu, S.; Gledhill, M.; Boiteau, R.; Dyhrman, S.; Rubin-Blum, M.; Shaked, Y.
10.1101/2023.03.15.532517 — microbiology — Posted on 2023-03-26
830 KSHV uses viral IL6 to expand infected immunosuppressive macrophages
Shimoda, M.; Inagaki, T.; Davis, R. R.; Merleev, A.; Tepper, C.; Maverakis, E. M.; Izumiya, Y.
10.1101/2023.03.05.531224 — immunology — Posted on 2023-03-26
833 Structural insights into the organization and channel properties of human Pannexin isoforms 1 and 3
Hussain, N.; Apotikar, A.; Pidathala, S.; Mukherjee, S.; Burada, A. P.; Sikdar, S. K.; Kutti, V. R.; Penmatsa, A.
10.1101/2022.09.09.507385 — biochemistry — Posted on 2023-03-26
837 The spatial arrangement of laminar thickness profiles in the human cortex scaffolds processing hierarchy
Saberi, A.; Paquola, C.; Wagstyl, K.; Hettwer, M. D.; Bernhardt, B.; Eickhoff, S. B.; Valk, S. L.
10.1101/2023.03.25.532115 — neuroscience — Posted on 2023-03-26
840 Unravelling individual rhythmic abilities using machine learning
Dalla Bella, S.; Janaqi, S.; Benoit, C.-E.; Farrugia, N.; Begel, V.; Verga, L.; Harding, E. E.; Kotz, S. A.
10.1101/2023.03.25.533209 — bioinformatics — Posted on 2023-03-26
845 RB loss sensitizes cells to replication-associated DNA damage by PARP inhibition
Zamalloa, L. G.; Pruitt, M. M.; Hermance, N. M.; Gali, H.; Flynn, R. L.; Manning, A. L.
10.1101/2023.03.25.532215 — cell biology — Posted on 2023-03-25
846 Genome-wide characterization of T cell responses to Bordetella pertussis reveals broad reactivity and similar polarization irrespective of childhood vaccination profiles.
da Silva Antunes, R.; Garrigan, E.; Quiambao, L.; Dhanda, S. K.; Marrama, D.; Westernberg, L.; Wang, E.; Sutherland, A.; Armstrong, S. K.; Brickman, T. J.; Sidney, J.; Frazier, A.; Merkel, T.; Peters, B.; Sette, A.
10.1101/2023.03.24.534182 — immunology — Posted on 2023-03-25
847 Dissecting cell state transitions by causal inference
Xu, L.; Cong, T.; Xu, H.; Yang, N.; Tian, C.; Yang, S.; Zhu, M.; Sinha, R.; Yamamoto, R.; Zhang, W.; Wang, J.; Lan, X.
10.1101/2023.02.08.527606 — systems biology — Posted on 2023-03-25
848 Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice
Ali Mondal, S.; Mann, S.; van der Linden, C.; Sathiaseelan, R.; Kamal, M.; Das, S.; Bubak, M.; Logan, S.; Miller, B. F.; Stout, M.
10.1101/2023.03.25.534216 — physiology — Posted on 2023-03-25
850 Clots reveal anomalous elastic behavior of fiber networks
Zakharov, A.; Awan, M.; Cheng, T.; Gopinath, A.; Lee, S.-J.; RAMASUBRAMANIAN, A.; Dasbiswas, K.
10.1101/2023.03.24.534185 — biophysics — Posted on 2023-03-25
851 An open-source FACS automation system for high-throughput cell biology
Wiener, D. M.; Huynh, E.; Jeyakumar, I.; Bax, S.; Sama, S.; Cabrera, J. P.; Todorova, V.; Vangipuram, M.; Vaid, S.; Otsuka, F.; Sakai, Y.; Leonetti, M. D.; Gomez-Sjoberg, R.
10.1101/2023.03.24.534165 — bioengineering — Posted on 2023-03-25
852 Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments
Oosterheert, W.; Blanc, F.; Roy, A.; Belyy, A.; Hofnagel, O.; Hummer, G.; Bieling, P.; Raunser, S.
10.1101/2023.03.25.534205 — biochemistry — Posted on 2023-03-25
854 Evidence for adaptive evolution towards high magnetic sensitivity of potential magnetoreceptor in songbirds
Langebrake, C.; Manthey, G.; Frederiksen, A.; Lugo Ramos, J. S.; Dutheil, J. Y.; Chetverikova, R.; Solov'yov, I.; Mouritsen, H.; Liedvogel, M.
10.1101/2023.03.25.534197 — evolutionary biology — Posted on 2023-03-25
855 Gut-associated functions are favored during microbiome assembly across C. elegans life
Zimmermann, J.; Piecyk, A.; Sieber, M.; Petersen, C.; Johnke, J.; Moitinho-Silva, L.; Kuenzel, S.; Bluhm, L.; Traulsen, A.; Kaleta, C.; Schulenburg, H.
10.1101/2023.03.25.534195 — evolutionary biology — Posted on 2023-03-25
856 Learning the functional landscape of microbial communities
Skwara, A.; Gowda, K.; Yousef, M.; Diaz-Colunga, J.; Raman, A. S.; Sanchez, A.; Tikhonov, M.; Kuehn, S.
10.1101/2023.03.24.534159 — ecology — Posted on 2023-03-25
858 EphrinA5 regulates cell motility by modulating the targeting of DNMT1 to the Ncam1 promoter via lncRNA/DNA triplex formation
Yildiz, C. B.; Kundu, T.; Gehrmann, J.; Koesling, J.; Ravaei, A.; Jakovcevski, M.; Pensold, D.; Zimmermann, O.; Rossetti, G.; Gesteira Costa Filho, I.; Zimmer-Bensch, G.
10.1101/2023.03.25.534129 — molecular biology — Posted on 2023-03-25
859 A highly conserved and globally prevalent cryptic plasmid is among the most numerous mobile genetic elements in the human gut
Fogarty, E. C.; Schechter, M. S.; Lolans, K.; Sheahan, M. L.; Veseli, I.; Moore, R.; Kiefl, E.; Moody, T.; Rice, P. A.; Yu, M. K.; Mimee, M.; Chang, E. B.; McLellan, S. L.; Willis, A. D.; Comstock, L. E.; Eren, A. M.
10.1101/2023.03.25.534219 — microbiology — Posted on 2023-03-25
860 Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites
Yip, A. Y. G.; King, O. G.; Omelchenko, O.; Kurkimat, S.; Horrocks, V.; Mostyn, P.; Danckert, N.; Ghani, R.; Satta, G.; Davies, F. J.; Clarke, T. B.; Mullish, B. H.; Marchesi, J. R.; McDonald, J. A. K.
10.1101/2023.03.25.533086 — microbiology — Posted on 2023-03-25
862 Integrated Drivers of Basal and Acute Immunity in Diverse Human Populations
Souquette, A.; Allen, E. K.; Oshansky, C. M.; Tang, L.; Wong, S.-s.; Jeevan, T.; Shi, L.; Pounds, S.; Elias, G.; Kuan, G.; Balmaseda, A.; Zapata, R.; Shaw-Saliba, K.; Van Damme, P.; Van Tendeloo, V.; Dib, J. C.; Ogunjimi, B.; Webby, R.; Schultz-Cherry, S.; Pekosz, A.; Rothman, R.; Gordon, A.; Thomas, P. G.
10.1101/2023.03.25.534227 — immunology — Posted on 2023-03-25
863 An intact oculomotor neural circuit in congenital blindness
Koba, C.; Crimi, A.; Collignon, O.; Ricciardi, E.; Hasson, U.
10.1101/2023.03.24.533989 — neuroscience — Posted on 2023-03-25
865 Label-free observation of individual solution phase molecules
Needham, L.-M.; Saavedra, C.; Rasch, J. K.; Sole-Barber, D.; Schweitzer, B. S.; Fairhall, A. J.; Vollbrecht, C. H.; Mehlenbacher, B.; Zhang, Z.; Tenbrake, L.; Pfeifer, H.; Chapman, E. R.; Goldsmith, R. H.
10.1101/2023.03.24.534170 — biophysics — Posted on 2023-03-25
867 Computational design of dynamic receptor--peptide signaling complexes applied to chemotaxis
Jefferson, R. E.; Oggier, A.; Fuglistaler, A.; Camviel, N.; Hijazi, M.; Rico Villarreal, A.; Arber, C.; Barth, P.
10.1101/2022.03.30.486413 — biophysics — Posted on 2023-03-25
868 Continuous Multiplexed Phage Genome Editing Using Recombitrons
Fishman, C. B.; Crawford, K. D.; Bhattarai-Kline, S.; Zhang, K. A.; Delgado-Gonzalez, A.; Shipman, S. L.
10.1101/2023.03.24.534024 — bioengineering — Posted on 2023-03-25
869 A lipopeptidomimetic of transcriptional activation domains selectively disrupts Med25 PPIs
Pattelli, O. N.; Martinez Valdivia, E.; Beyersdorf, M. S.; Regan, C. S.; Rivas, M.; Merajver, S. D.; Cierpicki, T.; Mapp, A. K.
10.1101/2023.03.24.534168 — biochemistry — Posted on 2023-03-25
870 Modification of DNA by a viral enzyme and charged tRNA
Silva, R. M. B.; Slyvka, A.; Lee, Y.-J.; Guan, C.; Lund, S. R.; Raleigh, E. A.; Skowronek, K.; Bochtler, M.; Weigele, P. R.
10.1101/2023.03.24.534169 — biochemistry — Posted on 2023-03-25
871 A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening
Rich, M. H.; Sharrock, A. V.; Mulligan, T. S.; Matthews, F.; Brown, A. S.; Lee-Harwood, H. R.; Williams, E. M.; Copp, J. N.; Little, R. F.; Francis, J. J.; Horvat, C. N.; Stevenson, L. J.; Owen, J. G.; Saxena, M. T.; Mumm, J. S.; Ackerley, D. F.
10.1101/2023.03.24.534183 — biochemistry — Posted on 2023-03-25
873 Massive genome reduction occurred prior to the origin of coral algal symbionts
Shah, S.; Dougan, K. E.; Chen, Y.; Lo, R.; Laird, G.; Fortuin, M. D. A.; Rai, S. K.; Murigneux, V.; Bellantuono, A. J.; Rodriguez-Lanetty, M.; Bhattacharya, D.; Chan, C. X.
10.1101/2023.03.24.534093 — genomics — Posted on 2023-03-25
876 The conserved protein CBA1 is required for vitamin B12 uptake in different algal lineages
Sayer, A. P.; Llavero-Pasquina, M.; Geisler, K.; Holzer, A.; Bunbury, F.; Mendoza-Ochoa, G. I.; Lawrence, A.; Warren, M. J.; Mehrshahi, P.; Smith, A. G.
10.1101/2023.03.24.534157 — biochemistry — Posted on 2023-03-25
878 Parasite hybridization promotes spreading of endosymbiotic viruses
Heeren, S.; Maes, I.; Sanders, M.; Lye, L.-F.; Arevalo, J.; Llanos Cuentas, A.; Garcia, L.; Lemey, P.; Beverley, S. M.; Cotton, J.; Dujardin, J.-C.; Van den Broeck, F.
10.1101/2023.03.24.534103 — evolutionary biology — Posted on 2023-03-25
879 Conserving genetic diversity during climate change:Niche marginality and discrepant monitoring capacity in Europe
Pearman, P. B.; Broennimann, O.; Albayrak, T.; Alves, P. C.; Bertola, L. D.; Biedrzycka, A.; Buzan, E.; Cubric-Curik, V.; Fedorca, A.; Godoy, J. A.; Hvilsom, C.; Klinga, P.; Konopinski, M. K.; Kopatz, A.; Laikre, L.; Lopez Fernandez, M.; Mergeay, J.; Neophytou, C.; Palsson, S.; Paz-Vinas, I.; Posledovich, D.; Roleckova, B.; Rungis, D.; Segelbacher, G.; Kavcic Sonnenschein, K.; Thurfjell, H.; Traeger, S.; Vernesi, C.; Vila, C.; Westergren, M.; Zachos, F. E.; Guisan, A.; Bruford, M.
10.1101/2023.03.24.533448 — ecology — Posted on 2023-03-25
882 Hierarchical Clustering and Omics Analysis Revealed Massive Molecular Shifts in a Tree under Combined Hypoxia and Salinity
Cisse, E.-H. M.; Jiang, B. H.; Yin, L.; Miao, L. F.; Zhou, J. J.; Mekontso, F. N.; Li, D. D.; Xiang, L. S.; Yang, F.
10.1101/2023.03.24.534131 — plant biology — Posted on 2023-03-25
885 Glioblastoma induces the recruitment and differentiation of hybrid neutrophils from skull bone marrow
Lad, M.; Beniwal, A.; Jain, S.; Shukla, P.; Jung, J.; Shah, S.; Yagnik, G.; Babikir, H.; Nguyen, A. T.; Gill, S.; Young, J. S.; Lui, A.; Salha, D.; Diaz, A.; Aghi, M. K.
10.1101/2023.03.24.534105 — cancer biology — Posted on 2023-03-25
889 Super-Resolved FRET and Co-Tracking in pMINFLUX
Cole, F.; Zaehringer, J.; Bohlen, J.; Schroeder, T.; Steiner, F.; Stefani, F. D.; Tinnefeld, P.
10.1101/2023.03.24.534096 — biophysics — Posted on 2023-03-25
890 xTrimoGene: An Efficient and Scalable Representation Learner for Single-Cell RNA-Seq Data
Gong, J.; Hao, M.; Zeng, X.; Liu, C.; Ma, J.; Cheng, X.; Wang, T.; Zhang, X.; Song, L.
10.1101/2023.03.24.534055 — bioinformatics — Posted on 2023-03-25
891 Non-linearity in motor unit velocity twitch dynamics: Implications for ultrafast ultrasound source separation
Lubel, E.; Grandi Sgambato, B.; Rohlen, R.; Ibanez, J.; Barsakcioglu, D.; Tang, M.-x.; Farina, D.
10.1101/2023.03.24.533983 — bioengineering — Posted on 2023-03-25
893 Unravelling the mystery of endemic versus translocated populations of the endangered Australian lungfish (Neoceratodus forsteri)
Biello, R.; Ghirotto, S.; Schmidt, D. J.; Fuselli, S.; Roberts, D. T.; Espinoza, T.; Hughes, J. M.; Bertorelle, G.
10.1101/2023.03.24.533984 — evolutionary biology — Posted on 2023-03-25
895 Environmental correlates of tree reproductive phenology in a tropical state of India - insights from a citizen science project
Anujan, K.; Mardian, J.; Luo, C.; Rajkumar, R.; SeasonWatch Citizen Scientist Network, ; Tasic, H.; Akseer, N.; Ramaswami, G.
10.1101/2023.03.24.533907 — ecology — Posted on 2023-03-25
900 Clonal differences underlie variable responses to sequential and prolonged treatment
Schaff, D. L.; Fasse, A. J.; White, P. E.; Vander Velde, R. J.; Shaffer, S. M.
10.1101/2023.03.24.534152 — systems biology — Posted on 2023-03-25
901 Intronic TNR-retained ISOPROPYLMALATE ISOMERASE LARGE SUBUNIT1 transcripts impair leaf development in Arabidopsis
Li, Y.; Li, R.; Kawade, K.; Sato, M.; Kuwahara, A.; Sasaki, R.; Oikawa, A.; Tsukaya, H.; Hirai, M. Y.
10.1101/2023.03.24.534132 — plant biology — Posted on 2023-03-25
903 High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen
Yang, W.-p.; Li, M.-q.; Ding, J.; Li, J.-y.; Wu, G.; Liu, B.; Gao, Y.-q.; Wang, G.; Luo, Q.-q.
10.1101/2023.03.23.533972 — physiology — Posted on 2023-03-25
904 Inhibition of CD40-TRAF6 signaling protects against aneurysm development and progression
Ommer-Blaesius, M.; Vajen, T.; Elster, C.; Verheyen, S.; Pfeiler, S.; Quast, C.; Odendahl, J.; Lang, A.; Lutgens, E.; Kelm, M.; Gerdes, N.
10.1101/2023.03.24.534110 — pharmacology and toxicology — Posted on 2023-03-25
905 Reduction, removal or replacement of sodium nitrite in a model of cured and cooked meat: a joint evaluation of consequences on microbiological issues in food safety, colon ecosystem and colorectal carcinogenesis
Gueraud, F.; Buisson, C.; Promeyrat, A.; Naud, N.; Fouche, E.; Bezirard, V.; Dupuy, J.; Plaisancie, P.; Helies-Toussaint, C.; Trouilh, L.; Martin, J.-L.; Jeuge, S.; Keuleyan, E.; Petit, N.; Aubry, L.; Theodorou, V.; Fremaux, B.; Olier, M.; Caderni, G.; Kostka, T.; Nassy, G.; Sante-Lhoutellier, V.; PIERRE, F. H.
10.1101/2023.03.24.531666 — pathology — Posted on 2023-03-25
906 Absence of Telomerase Leads to Immune Response and Tumor Regression in Zebrafish Melanoma
Lopes-Bastos, B.; Nabais, J.; Ferreira, T.; El-Mai, M.; Bird, M.; Targen, S.; Kang, D.; Yue, J.-X.; Carvalho, T.; Ferreira, M. G.
10.1101/2023.03.24.534079 — cancer biology — Posted on 2023-03-25
907 VRK3 depletion induces cell cycle arrest and metabolic reprogramming of Pontine Diffuse Midline Glioma (DMG)-K27 altered cells
Menez, V.; Kergrohen, T.; Sasha, T.; Silva-Evangelista, C.; Ledret, L.; Auffret, L.; Subecz, C.; Lancien, M.; Ajlil, Y.; Beccaria, K.; Blauwblomme, T.; Oberlin, E.; Grill, J.; Castel, D.; Debily, M.-A.
10.1101/2023.03.24.533960 — cancer biology — Posted on 2023-03-25
908 Replication fork plasticity upon replication stress requires rapid nuclear actin polymerization
Palumbieri, M. D.; Merigliano, C.; Gonzalez-Acosta, D.; von Kaenel, T.; Welter, B.; Stoy, H.; Krietsch, J.; Ulferts, S.; Sanchi, A.; Grosse, R.; Chiolo, I.; Lopes, M.
10.1101/2023.03.24.534097 — cancer biology — Posted on 2023-03-25
911 Video-rate three-photon imaging in deep Drosophila brain based on a single Cr:forsterite oscillator
Chou, L.-T.; Wu, S.-H.; Hung, H.-H.; Jang, J.-C.; Chen, C.-M.; Chang, T.-C.; Lin, W.-Z.; Chu, L.-A.; Sun, C.-K.; Kartner, F. X.; Ivanov, A. A.; Chu, S.-W.; Chia, S.-H.
10.1101/2023.03.23.533955 — bioengineering — Posted on 2023-03-25
912 Production of extracellular polymeric substances in granular sludge under selection for Accumulibacter and Competibacter
Guimaraes, L. B.; Gubser, N.; Lin, Y.; Zlopasa, J.; Felz, S.; Tomas Martinez, S.; Pronk, M.; Neu, T. R.; Dueholm, M. K. D.; Albertsen, M.; da Costa, R. H. R.; Nielsen, P. H.; van Loosdrecht, M. C. M.; Weissbrodt, D. G.
10.1101/2023.03.24.534144 — bioengineering — Posted on 2023-03-25
914 Pulmonary vein flow split effects in patient-specific simulations of left atrial flow
Duran, E.; Garcia-Villalba, M.; Martinez-Legazpi, P.; Gonzalo, A.; McVeigh, E.; Kahn, A. M.; Bermejo, J.; Flores, O.; del Alamo, J. C.
10.1101/2023.03.24.534045 — bioengineering — Posted on 2023-03-25
917 Fast centromeric repeat turnover provides a glimpse into satellite DNA evolution in Nothobranchius annual killifishes
Volenikova, A.; Luksikova, K.; Mora, P.; Pavlica, T.; Altmanova, M.; Stundlova, J.; Pelikanova, S.; Simanovsky, S. A.; Jankasek, M.; Reichard, M.; Nguyen, P.; Sember, A.
10.1101/2023.03.23.534043 — genetics — Posted on 2023-03-25
923 Cbp1-Cren7 chromatinization of CRISPR arrays favours transcription from leader- over cryptic promoters
Blombach, F.; Sykora, M.; Case, J.; Feng, X.; Baquero, D. P.; Fouqueau, T.; Phung, D. K.; Barker, D.; Krupovic, M.; She, Q.; Werner, F.
10.1101/2023.03.24.534125 — microbiology — Posted on 2023-03-25
924 Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation
Nikaein, N.; Tuerxun, K.; Cedersund, G.; Eklund, D.; Kruse, R.; Sarndahl, E.; Nanberg, E.; Thonig, A.; Repsilber, D.; Persson, A.; Nyman, E.; X-HiDE Consortium,
10.1101/2023.03.24.533939 — systems biology — Posted on 2023-03-25
929 Understanding the phytochemical diversity of plants: Quantification, variation and ecological function
Petren, H.; Ania, R. A.; Aragam, K. S.; Bräutigam, A.; Eckert, S.; Heinen, R.; Jakobs, R.; Ojeda-Prieto, L.; Popp, M.; Sasidharan, R.; Schnitzler, J.-P.; Steppuhn, A.; Thon, F.; Tschikin, S.; Unsicker, S. B.; van Dam, N. M.; Weisser, W. W.; Wittmann, M. J.; Yepes, S.; Ziaja, D.; Müller, C.; Junker, R. R.
10.1101/2023.03.23.533415 — ecology — Posted on 2023-03-25
935 Liposomal aggregates sustain the release of rapamycin and protect cartilage from friction
Bordon, G.; Ramakrishna, S. N.; Edalat, S. G.; Eugster, R.; Arcifa, A.; Aleandri, S.; Frank Bertoncelj, M.; Isa, L.; Crockett, R.; Distler, O.; Luciani, P.
10.1101/2023.03.23.533793 — pharmacology and toxicology — Posted on 2023-03-25
936 Western diet dampens T regulatory cell function to fuel hepatic inflammation in nonalcoholic fatty liver disease
Chaudhary, S.; Rai, R. P.; Pal, P. B.; Tedesco, D.; Singhi, A. D.; Monga, S. P.; Grakoui, A.; Iyer, S. S.; Raeman, R.
10.1101/2023.03.23.533977 — pathology — Posted on 2023-03-25
937 Analysis of evolutionary dynamics and clonal architecture in prostate cancer
Conway, J.; Tewari, A. K.; Camp, S. Y.; Han, S.; Crowdis, J.; He, M. X.; Nyame, Y. A.; AlDubayan, S. H.; Schultz, N.; Szallasi, Z.; Pomerantz, M. M.; Freedman, M. L.; Fong, L.; Nelson, P. S.; Brown, M.; Salari, K.; Van Allen, E.
10.1101/2023.03.23.533974 — cancer biology — Posted on 2023-03-25
938 Modeling, dissecting, and subtyping of E-Cadherin inactivation-associated diffuse-type gastric adenocarcinoma
Zou, G.; Huang, Y.; Zhang, S.; Ko, K.-P.; Kim, B. J.; Zhang, J.; Pizzi, M. P.; Jun, S.; Niu, N.; Wang, H.; Song, S.; Ajani, J. A.; Park, J.-I.
10.1101/2023.03.23.533976 — cancer biology — Posted on 2023-03-25
939 Human USP18 protects diverse cancer lineages from Type I Interferon independently of its canonical catalytic function
Wes, P. D.; Kessler, B. M.; Pinto-Fernandez, A.; Jove, V.; Wheeler, H.; Lee, C. W.; Healy, D. R.; Levine, K.; Ralph, E. C.; Giddabasappa, A.; Loria, P.; Yamaguchi, M.; Casimiro-Garcia, A.; Frattini, V.; Wang, F.; Yang, B.
10.1101/2023.03.23.533924 — cancer biology — Posted on 2023-03-25
940 From Microstates to Macrostates in the Conformational Dynamics of GroEL: a Single-Molecule FRET Study
Liebermann, D. G.; Jungwirth, J.; Riven, I.; Barak, Y.; Levy, D.; Horovitz, A.; Haran, G.
10.1101/2023.03.23.533937 — biophysics — Posted on 2023-03-25
942 Supervised learning of high-confidence phenotypic subpopulations from single-cell data
Ren, T.; Chen, C.; Danilov, A. V.; Liu, S.; Guan, X.; Du, S.; Wu, X.; Sherman, M. H.; Spellman, P. T.; Coussens, L. M.; Adey, A. C.; Mills, G. B.; Wu, L.-Y.; Xia, Z.
10.1101/2023.03.23.533712 — bioinformatics — Posted on 2023-03-25
944 MutationExplorer - a webserver for mutation of proteins and 3D visualization of energetic impacts
Philipp, M.; Moth, C. W.; Ristic, N.; Tiemann, J. K. S.; Seufert, F.; Meiler, J.; Hildebrand, P.-W.; Stein, A.; Wiegreffe, D.; Staritzbichler, R.
10.1101/2023.03.23.533926 — bioinformatics — Posted on 2023-03-25
947 Virtual screening of antimicrobial plant extracts by machine-learning classification of chemical compounds in semantic space
Yabuuchi, H.; Hayashi, K.; Shigemoto, A.; Fujiwara, M.; Nomura, Y.; Nakashima, M.; Ogusu, T.; Mori, M.; Tokumoto, S.-i.; Miyai, K.
10.1101/2023.03.23.533934 — bioinformatics — Posted on 2023-03-25
948 Somatic small-variant calling methods in Illumina DRAGEN™ Secondary Analysis
Scheffler, K.; Catreux, S.; O'Connell, T.; Jo, H.; Jain, V.; Heyns, T.; Yuan, J.; Murray, L.; Han, J.; Mehio, R.
10.1101/2023.03.23.534011 — bioinformatics — Posted on 2023-03-25
951 Glycopolymer-conjugated antigens as an inverse vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
Cao, S.; Maulloo, C. D.; Raczy, M. M.; Sabados, M.; Slezak, A. J.; Nguyen, M.; Solanki, A.; Wallace, R. P.; Shim, H.-N.; Wilson, D. S.; Hubbell, J. A.
10.1101/2023.03.23.534004 — bioengineering — Posted on 2023-03-25
952 A simple method to dramatically increase C. elegans germline microinjection efficiency
Gibney, T. V.; Favichia, M.; Latifi, L.; Medwig-Kinney, T. N.; Matus, D. Q.; McIntyre, D. C.; Arrigo, A. B.; Branham, K. R.; Bubrig, L. T.; Ghaddar, A.; Jiranek, J. A.; Liu, K. E.; Marcucci, C. G.; Porter, R. J.; Pani, A. M.
10.1101/2023.03.23.533855 — genetics — Posted on 2023-03-25
953 Understanding Complex Trait Susceptibilities and Ethnical Diversity in a Sample of 4,145 Russians Through Analysis of Clinical and Genetic Data
Usoltsev, D.; Kolosov, N.; Rotar, O.; Loboda, A.; Boyarinova, M.; Moguchaya, E.; Kolesova, E.; Erina, A.; Tolkunova, K.; Rezapova, V.; Melnik, O.; Freylikhman, O.; Paskar, N.; Alieva, A.; Baranova, E.; Bazhenova, E.; Beliaeva, O.; Vasilyeva, E.; Kibkalo, S.; Skitchenko, R.; Babenko, A.; Sergushichev, A.; Dushina, A.; Lopina, E.; Basyrova, I.; Libis, R.; Duplyakov, D.; Cherepanova, N.; Donner, K.; Laiho, P.; Kostareva, A.; Konradi, A.; Shlyakhto, E.; Palotie, A.; Daly, M. J.; Artomov, M.
10.1101/2023.03.23.534000 — genetics — Posted on 2023-03-25
957 Coexistence of many species under a random competition-colonization trade-off
Miller, Z. R.; Clenet, M.; Della Libera, K.; Massol, F.; Allesina, S.
10.1101/2023.03.23.533867 — ecology — Posted on 2023-03-25
958 ZFP281 coordinates DNMT3 and TET1 for transcriptional and epigenetic control in pluripotent state transitions
Huang, X.; Balmer, S.; Lyu, C.; Xiang, Y.; Malik, V.; Wang, H.; Zhang, Y.; Xie, W.; Hadjantonakis, A.-K.; Zhou, H.; Wang, J.
10.1101/2023.03.24.534143 — developmental biology — Posted on 2023-03-25
962 High-Content Screening to Identify Inhibitors of Dengue Virus Replication
Hoffstadt, J. G.; Wotring, J. W.; Porter, S.; Halligan, B. S.; O'Meara, M. J.; Tai, A. W.; Sexton, J. Z.
10.1101/2023.03.24.534108 — cell biology — Posted on 2023-03-25
964 Elastomeric Pillar Cages Modulate Actomyosin Contractility of Epithelial Microtissues by Substrate Stiffness and Topography
Esser, L.; Springer, R.; Dreissen, G.; Lövenich, L.; Konrad, J.; Hampe, N.; Merkel, R.; Hoffmann, B.; Noetzel, E.
10.1101/2023.03.24.534106 — cell biology — Posted on 2023-03-25
965 Transformations of sensory information in the brain reflect a changing definition of optimality
Manning, T. S.; Alexander, E.; Cumming, B. G.; DeAngelis, G. C.; Huang, X.; Cooper, E. A.
10.1101/2023.03.24.534044 — neuroscience — Posted on 2023-03-25
966 Cortical contributions to the perception of loudness and hyperacusis
McGill, M.; Kremer, C.; Stecyk, K.; Clayton, K.; Skerleva, D.; Hancock, K.; Kujawa, S. G.; Polley, D. B.
10.1101/2023.03.24.534013 — neuroscience — Posted on 2023-03-25
969 Repeated exposure to high-THC Cannabis smoke during gestation alters sex ratio, behavior, and amygdala gene expression of Sprague Dawley rat offspring
Sandini, T. M.; Onofrychuk, T. J.; Roebuck, A. J.; Hammond, A.; Udenze, D.; Hayat, S.; Herdzik, M. A.; McElroy, D. L.; Orvold, S. N.; Greba, Q.; Laprairie, R. B.; Howland, J. G.
10.1101/2023.03.23.533930 — neuroscience — Posted on 2023-03-25
972 An intact oculomotor neural circuit in congenital blindness
Crimi, A.; Koba, C.; Collignon, O.; Ricciardi, E.; Hasson, U.
10.1101/2023.03.24.533989 — neuroscience — Posted on 2023-03-25
973 Multi-Scale Spiking Network Model of Human Cerebral Cortex
Pronold, J.; van Meegen, A.; Vollenbroeker, H.; Shimoura, R.; Senden, M.; Hilgetag, C.; Bakker, R.; van Albada, S.
10.1101/2023.03.23.533968 — neuroscience — Posted on 2023-03-25
976 Deficits in mitochondrial function and glucose metabolism seen in sporadic and familial Alzheimers disease derived Astrocytes are ameliorated by increasing hexokinase 1 expression.
Bell, S. M.; Wareing, H.; Hamshaw, A.; De, S.; New, E.; Shaw, P. J.; De Marco, M.; Venneri, A.; Blackburn, D. J.; Ferraiuolo, L.; Mortiboys, H. J.
10.1101/2023.03.23.534020 — neuroscience — Posted on 2023-03-25
978 Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo
Donzelli, S.; OSullivan, S.; Mahul-Mellier, A.-L.; Ulusoy, A.; Fusco, G.; Kumar, S. T.; Chiki, A.; Burtscher, J.; Boussouf, M. L. D.; Rostami, I.; De Simone, A. D. S.; Di Monte, D. A.; Lashuel, H. A.
10.1101/2023.03.24.534149 — neuroscience — Posted on 2023-03-25
979 A neuronal least-action principle for real-time learning in cortical circuits
Senn, W.; Dold, D.; Kungl, A.; Ellenberger, B.; Jordan, J.; Bengio, Y.; Sacramento, J.; Petrovici, M. A.
10.1101/2023.03.25.534198 — neuroscience — Posted on 2023-03-25
980 Spinal sensorimotor circuits play a prominent role in hindlimb locomotor recovery after staggered thoracic lateral hemisections but cannot restore posture and interlimb coordination during quadrupedal locomotion in adult cats
Audet, J.; Yassine, S.; Lecomte, C. G.; Mari, S.; Soucy, F.; Morency, C.; Merlet, A. N.; Harnie, J.; Beaulieu, C.; Gendron, L.; Rybak, I. A.; Prilutsky, B. I.; Frigon, A.
10.1101/2023.03.23.533936 — neuroscience — Posted on 2023-03-25
981 Oligodendrocytes in human iPS cell-derived cortical grafts remyelinate adult rat and human cortical neurons
Martinez-Curiel, R.; Jansson, L.; Tsupykov, O.; Avaliani, N.; Aretio-Medina, C.; Hidalgo, I.; Monni, E.; Bengzon, J.; Skibo, G.; Lindvall, O.; Kokaia, Z.; Palma-Tortosa, S.
10.1101/2023.03.24.534133 — neuroscience — Posted on 2023-03-25
983 TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy
Edwards, G. A.; Wood, C. A.; Nguyen, Q.; Kim, P. J.; Gomez-Gutierrez, R.; Park, K.-W.; Zurhellen, C.; Al-Ramahi, I.; Jankowsky, J. L.
10.1101/2023.03.23.533978 — neuroscience — Posted on 2023-03-25
986 Alpha 9 integrin expression enables reconstruction of the spinal cord sensory pathway.
Stepankova, K.; Smejkalova, B.; Machova Urdzikova, L.; Havelikova, K.; Verhaagen, J.; deWinter, F.; Herynek, V.; Kwok, J. C. F.; Fawcett, J. C. F.; Jendelova, P.
10.1101/2023.03.24.534172 — neuroscience — Posted on 2023-03-25
987 Thalamic regulation of ocular dominance plasticity in adult visual cortex
Qin, Y.; Ahmadlou, M.; Suhai, S.; Neering, P.; de Kraker, L.; Heimel, J. A.; Levelt, C. N.
10.1101/2023.03.23.533941 — neuroscience — Posted on 2023-03-25
990 A novel paradigm for operant social learning in rats
Rautio, I. V.; Holmberg, E. H.; Kurup, D.; Dunn, B. A.; Whitlock, J. R.
10.1101/2023.03.24.534145 — animal behavior and cognition — Posted on 2023-03-25
992 Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures
Kastlmeier, M. T.; Gonzalez Rodriguez, E.; Cabanis, P.; Guenther, E. M.; Koenig, A.-C.; Han, L.; Hauck, S.; See, F.; Asgharpour, S.; Bukas, C.; Burgstaller, G.; Piraud, M.; Lehmann, M.; Hatz, R. A.; Behr, J.; Stoeger, T.; Hilgendorff, A.; Voss, C.
10.1101/2022.12.20.521114 — cell biology — Posted on 2023-03-25
994 Cortical cell assemblies and their underlying connectivity: an in silico study
Ecker, A.; Egas Santander, D.; Bolanos Puchet, S.; Isbister, J. B.; Reimann, M. W.
10.1101/2023.02.24.529863 — neuroscience — Posted on 2023-03-25
995 Intra-Host Mutation Rate of Acute SARS-CoV-2 Infection During the Initial Pandemic Wave
El Haddad, K.; Adhikari, T. M.; Zheng, T.; Cheng, Y.-W.; Leng, X.; Zhang, X.; Rhoads, D.; Ko, J.; Worley, S.; Li, J.; Rubin, B.; Esper, F.
10.1101/2023.03.24.534062 — evolutionary biology — Posted on 2023-03-25
997 In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia
Bakina, O.; Conrad, T.; Mitic, N.; Vidal, R. O.; Obrusnik, T.; Sai, S.; Nolte, C.; Semtner, M.; Kettenmann, H.
10.1101/2023.03.22.533782 — immunology — Posted on 2023-03-25
998 Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC
Ding, S.; Tolbert, W. D.; Zhu, H.; Lee, D.; Higgins, T.; Zhao, X.; Nguyen, D.; Sherburn, R.; Richard, J.; Gendron-Lepage, G.; Medjahed, H.; Mohammadi, M.; Abrams, C.; Pazgier, M.; Smith, A. B.; Finzi, A.
10.1101/2023.03.23.533923 — immunology — Posted on 2023-03-25
999 Reactive astrocytes associated with prion disease impair the blood brain barrier
Kushwaha, R.; Li, Y.; Makarava, N.; Pandit, N. P.; Molesworth, K.; Birukov, K. G.; Baskakov, I. V.
10.1101/2023.03.21.533684 — neuroscience — Posted on 2023-03-25
1000 Genetic and dietary modulators of the inflammatory response in the gastro-intestinal tract of the BXD mouse genetic reference population
Li, X.; Morel, J.-D.; Benegiamo, G.; Poisson, J.; Bachmann, A.; Rapin, A.; Williams, E. G.; Perino, A.; Schoonjans, K.; Bou Sleiman, M. S.; Auwerx, J.
10.1101/2023.03.22.533818 — systems biology — Posted on 2023-03-25
1001 Dopamine D1-receptor Organization Contributes to Functional Brain Architecture
Pedersen, R.; Johansson, J.; Nordin, K.; Rieckmann, A.; Wahlin, A.; Nyberg, L.; Backman, L.; Salami, A.
10.1101/2023.03.24.534086 — neuroscience — Posted on 2023-03-25
1002 Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor
Li, Q.; Nemecz, A.; Ayme, G.; Prevost, M. S.; Pons, S.; Dejean de la Batie, G.; Barilone, N.; Baachaoui, R.; Maskos, U.; Lafaye, P.; Corringer, P.-J.
10.1101/2023.01.03.522562 — neuroscience — Posted on 2023-03-24
1004 Two long-axis dimensions of hippocampal cortical integration support memory function across the adult lifespan
Nordin, K.; Pedersen, R.; Falahati, F.; Johansson, J.; Grill, F.; Andersson, M.; Korkki, S.; Backman, L.; Zalesky, A.; Rieckmann, A.; Nyberg, L.; Salami, A.
10.1101/2023.03.24.534115 — neuroscience — Posted on 2023-03-25
1006 A Multiomic Analysis Reveals How Breast Cancers Disseminated to the Bone Marrow Acquire Aggressive Phenotypes through Tumor-Stroma Tunnels
Sinha, S.; Callow, B.; Farfel, A.; Roy, S.; Chen, S.; Rajendran, S.; Buschhaus, J.; Luker, K. E.; Ghosh, P.; Luker, G. D.
10.1101/2023.03.18.533175 — cancer biology — Posted on 2023-03-24
1007 Amplified cortical neural responses as animals learn to use novel activity patterns
Akitake, B.; Douglas, H. M.; LaFosse, P. K.; Deveau, C. E.; Li, A. J.; Ryan, L. N.; Duffy, S. P.; Zhou, Z.; Deng, Y.; Histed, M. H.
10.1101/2022.07.10.499496 — neuroscience — Posted on 2023-03-24
1010 Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables
Brummer, A. B.; Xella, A.; Woodall, R.; Adhikarla, V.; Cho, H.; Gutova, M. B.; Brown, C. E.; Rockne, R. C.
10.1101/2022.09.22.508748 — cancer biology — Posted on 2023-03-24
1011 Gene panel selection for targeted spatial transcriptomics
Zhang, Y.; Petukhov, V.; Biederstedt, E.; Que, R.; Zhang, K.; Kharchenko, P. V.
10.1101/2023.02.03.527053 — bioinformatics — Posted on 2023-03-24
1012 Three sequential sex chromosome - autosome fusions in Heliconius butterflies
Rueda-M, N.; Jiggins, C. D.; Pardo-Diaz, C.; McMillan, W. O.; McCarthy, S.; Kozak, K. M.; Arias, C. F.; Ready, J.; Durbin, R.; Montejo-Kovacevich, G.; Meier, J.; Salazar, C.
10.1101/2023.03.06.531374 — evolutionary biology — Posted on 2023-03-24
1014 Maximal interferon induction by influenza lacking NS1 is infrequent owing to requirements for replication and export
Vicary, A. C.; Mendes, M.; Swaminath, S.; Lekbua, A.; Reddan, J.; Rodriguez, Z. K.; Russell, A. B.
10.1101/2022.10.24.513459 — microbiology — Posted on 2023-03-24
1015 Inactivation mechanisms of Influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS.
David, S. C.; Vadas, O.; Glas, I.; Schaub, A.; Luo, B.; D'Angelo, G. C.; Paz Montoya, J.; Bluvshtein, N.; Hugentobler, W.; Klein, L.; Motos, G.; Pohl, M.; Violaki, K.; Nenes, A.; Krieger, U.; Stertz, S.; Peter, T.; Kohn, T.
10.1101/2022.11.01.514690 — microbiology — Posted on 2023-03-24
1019 An adhesion signaling axis regulates the establishment of the cortical glial scaffold.
Wong, W.; Estep, J. A.; Treptow, A. M.; Rajabli, N.; Jahncke, J. N.; Ubina, T.; Wright, K. M.; Riccomagno, M. M.
10.1101/2022.08.02.502565 — neuroscience — Posted on 2023-03-24
1020 Transcription-replication interactions reveal principles of bacterial genome regulation
Pountain, A.; Jiang, P.; Yao, T.; Homaee, E.; Guan, Y.; Podkowik, M.; Shopsin, B.; Torres, V. J.; Golding, I.; Yanai, I.
10.1101/2022.10.22.513359 — systems biology — Posted on 2023-03-24
1022 Standardization of suspension and imaging mass cytometry readouts for clinical decision making
Casanova, R.; Xu, S.; Sivapatham, S.; Jacobs, A.; Engler, S.; Tumor Profiler Consortium, ; Levesque, M. P.; Dummer, R.; Bodenmiller, B.; Chevrier, S.
10.1101/2023.03.19.531228 — cancer biology — Posted on 2023-03-24
1023 Cellular heterogeneity of the developing worker honey bee (Apis mellifera) pupa: a single cell transcriptomics analysis
Patir, A.; Raper, A.; Fleming, R.; Henderson, B. E. P.; Murphy, L.; Henderson, N. C.; Clark, E. L.; Freeman, T. C.; Barnett, M. W.
10.1101/2023.03.20.533557 — genomics — Posted on 2023-03-24
1024 Split-intein Gal4 provides intersectional genetic labeling that is fully repressible by Gal80
Ewen-Campen, B.; Luan, H.; Xu, J.; Singh, R.; Joshi, N.; Thakkar, T.; Berger, B.; White, B.; Perrimon, N.
10.1101/2023.03.24.534001 — genetics — Posted on 2023-03-24
1025 Microbiomes of blood feeding triatomines in the context of their predatory relatives and the environment
Tarabai, H.; Floriano, A. M.; Zima, J.; Filova, N.; Brown, J. J.; Roachell, W.; Smith, R. L.; Beatty, N. L.; Vogel, K. J.; Novakova, E.
10.1101/2023.03.24.534010 — ecology — Posted on 2023-03-24
1027 Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning
Radford, C. E.; Schommers, P.; Gieselmann, L.; Crawford, K. H.; Dadonaite, B.; Yu, T. C.; Dingens, A. S.; Overbaugh, J.; Klein, F.; Bloom, J. D.
10.1101/2023.03.23.533993 — immunology — Posted on 2023-03-24
1029 A Single-Nucleus Atlas of Seed-to-Seed Development in Arabidopsis
Lee, T. A.; Nobori, T.; Illouz-Eliaz, N.; Xu, J.; Jow, B.; Nery, J. R.; Ecker, J. R.
10.1101/2023.03.23.533992 — plant biology — Posted on 2023-03-24
1030 Comparison of antibiotic protein binding in human plasma vs. rabbit plasma
Pesta, M.; Zeitlinger, M.; Datler, P.; Scheriau, G.; Wohlrab, P.; Eberl, S.; Lackner, E.; Franz, C.; Jaeger, W.; Maier-Salamon, A.; Tschernko, E.
10.1101/2023.03.23.534048 — pharmacology and toxicology — Posted on 2023-03-24
1031 Shifting the selectivity of pyridopyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily
Rak, M.; Tesch, R.; Berger, L. M.; Shevchenko, E.; Raab, M.; Tjaden, A.; Zhubi, R.; Balourdas, D.-I.; Joerger, A. C.; Poso, A.; Kraemer, A.; Elson, L.; Lucic, A.; Kronenberger, T.; Hanke, T.; Strebhardt, K.; Sanhaji, M.; Knapp, S.
10.1101/2023.03.24.534094 — biochemistry — Posted on 2023-03-24
1032 Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancer.
Khan, M. M.; Frustino, J.; Villa, A.; Nguyen, B.-C.; Woo, S.-B.; Johnson, W. E.; Varelas, X.; Kukuruzinska, M.; Monti, S.
10.1101/2023.03.24.534064 — genomics — Posted on 2023-03-24
1033 High-resolution functional description of vaginal microbiomes in health and disease
Holm, J. B.; France, M.; Gajer, P.; Ma, B.; Brotman, R. M.; Shardell, M.; Forney, L.; Ravel, J.
10.1101/2023.03.24.533147 — genomics — Posted on 2023-03-24
1034 The Hypolimnas misippus genome supports a common origin of the W chromosome in Lepidoptera
Orteu, A.; McCarthy, S. A.; Hornett, E. A.; Gemmel, M.; Reynolds, L. A.; Warren, I. A.; Gordon, I. J.; Hurst, G. D. D.; Durbin, R.; Martin, S. H.; Jiggins, C. D.
10.1101/2023.03.24.533969 — genomics — Posted on 2023-03-24
1037 Elevated ENO2 Disrupts VSMCs Homeostasis Facilitating the Development of Aortic Dissection
Cai, W.; Zhang, L.; Lin, J.-J.; Zou, Q.; Wang, C.; Yang, X.; Wu, X.; Ye, J.-q.; Zheng, H.; Zhang, L.; Zhong, L.; Li, X.; Chen, K.; jiangbin, W.; Chen, L.; Li, Y.
10.1101/2023.03.23.534041 — molecular biology — Posted on 2023-03-24
1039 DIP-MS: A novel ultra-deep interaction proteomics for the deconvolution of protein complexes
Frommelt, F.; Fossati, A.; Uliana, F.; Wendt, F.; Xue, P.; Heusel, M.; Wollscheid, B.; Aebersold, R.; Ciuffa, R.; Gstaiger, M.
10.1101/2023.03.22.533843 — systems biology — Posted on 2023-03-24
1041 Genetic structure and diversity of rfb locus of pathogenic species of genus Leptospira
Ferreira, L. C. A.; Ferreira Filho, L. d. F. A.; Cosate, M. R. V.; Sakamoto, T.
10.1101/2023.03.23.533916 — bioinformatics — Posted on 2023-03-24
1042 JUMP Cell Painting dataset: morphological impact of 136,000 chemical and genetic perturbations
Chandrasekaran, S. N.; Ackerman, J.; Alix, E.; Ando, D. M.; Arevalo, J.; Bennion, M.; Boisseau, N.; Borowa, A.; Boyd, J. D.; Brino, L.; Byrne, P. J.; Ceulemans, H.; Ch'ng, C.; Cimini, B. A.; Clevert, D.-A.; Deflaux, N.; Doench, J. G.; Dorval, T.; Doyonnas, R.; Dragone, V.; Engkvist, O.; Faloon, P. W.; Fritchman, B.; Fuchs, F.; Garg, S.; Gilbert, T. J.; Glazer, D.; Gnutt, D.; Goodale, A.; Grignard, J.; Guenther, J.; Han, Y.; Hanifehlou, Z.; Hariharan, S.; Hernandez, D.; Horman, S. R.; Hormel, G.; Huntley, M.; Icke, I.; Iida, M.; Jacob, C. B.; Jaensch, S.; Khetan, J.; Kost-Alimova, M.; Krawiec,
10.1101/2023.03.23.534023 — bioinformatics — Posted on 2023-03-24
1044 Natural mutations of human XDH promote the nitrite (NO2-)-reductase capacity of xanthine oxidoreductase: a novel mechanism to promote redox health?
MASSIMO, G.; Khambata, R. S.; Chapman, T.; Birchall, K.; Shabbir, A.; Dyson, N.; Rathod, K.; Borghi, C.; Ahluwalia, A.
10.1101/2023.03.24.533749 — biochemistry — Posted on 2023-03-24
1046 Karyopherin mimicry explains how the HIV capsid penetrates nuclear pores
Dickson, C. F.; Hertel, S.; Ruan, J.; Ariotti, N.; Tuckwell, A.; Li, N.; Al-Izzi, S.; Sierecki, E.; Gambin, Y.; Morris, R. G.; Towers, G. J.; Boecking, T.; Jacques, D. A.
10.1101/2023.03.23.534032 — biochemistry — Posted on 2023-03-24
1048 Large-scale epidemiological study on feline autosomal dominant polycystic kidney disease and identification of novel PKD1 gene variants
Shitamori, F.; Nonogaki, A.; Motegi, T.; Matsumoto, Y.; Sakamoto, M.; Tanizawa, Y.; Nakamura, Y.; Yonezawa, T.; Momoi, Y.; Maeda, S.
10.1101/2023.03.23.533873 — molecular biology — Posted on 2023-03-24
1051 Ornithodoros maritimus as a vector of Babesia sp. YLG in Yellow-legged gull (Larus michahellis) nests
Bonsergent, C.; Vittecoq, M.; Leray, C.; Jouglin, M.; Buysse, M.; McCoy, K.; Malandrin, L.
10.1101/2023.03.24.534071 — microbiology — Posted on 2023-03-24
1052 Uropathogenic Escherichia coli population structure and antimicrobial susceptibility in Norfolk, UK
Carter, C.; Hutchison, A.; Rudder, S.; Trotter, E.; Waters, E.; Elumogo, N.; Langridge, G.
10.1101/2023.03.24.533965 — microbiology — Posted on 2023-03-24
1053 Production of 130 diterpenoids by combinatorial biosynthesis in yeast
Bathe, U.; Schmidt, J.; Frolov, A.; Soboleva, A.; Frank, O.; Dawid, C.; Tissier, A. F.
10.1101/2023.03.24.534067 — synthetic biology — Posted on 2023-03-24
1056 AG3D: A low-cost educational 3D printable toolkit for agarose gel electrophoresis
Barwick, M. W.; Fanucci, S.; Mbanxa, S.; Buthelezi, K.; Jukes, M. D.; Abrahams, G. L.; Prinsloo, E.
10.1101/2023.03.22.533785 — scientific communication and education — Posted on 2023-03-24
1057 Neural and behavioural dynamics of the individual and collective self(s)
Huepe, D.; Canales-Johnson, A.; Rivera-Rei, A.; Ibanez, A.; Bekinschtein, T. A.
10.1101/2023.03.22.533659 — animal behavior and cognition — Posted on 2023-03-24
1058 Host and microbiome jointly contribute to adaptation to a complex environment
Petersen, C.; Hamerich, I. K.; Adair, K. L.; Griem-Krey, H.; Oliva, M. T.; Hoeppner, M. P.; Bohannan, B. J. M.; Schulenburg, H.
10.1101/2023.03.22.533853 — evolutionary biology — Posted on 2023-03-24
1061 The immune receptor SNC1 monitors helper NLRs targeted by a bacterial effector
Wang, M.; Chen, J.; Wu, R.; Guo, H.; Chen, Y.; Li, Z.; Wei, L.; Liu, C.; He, S.; Du, M.; Guo, Y.; Peng, Y.-L.; Jones, J. D.; Weigel, D.; Huang, J.; Zhu, W.
10.1101/2023.03.23.533910 — plant biology — Posted on 2023-03-24
1062 Artificially cultivated duckweed: a high-efficiency starch producer
Fang, Y.; Guo, L.; Wang, S.; Xiao, Y.; Ding, Y.; Jin, Y.; Tian, X.; Du, A.; Liao, Z.; He, K.; Chen, S.; Zhao, Y.; Tan, L.; Yi, Z.; Che, Y.; Chen, L.; Li, J.; Zhao, L.; Zhang, P.; Gu, Z.; Zhang, F.; Hong, Y.; Zhang, Q.; Zhao, H.
10.1101/2023.03.23.533730 — plant biology — Posted on 2023-03-24
1063 Cancer Immunotherapy through Tissue Adhering Polymers
Borthwick, N. J.; Maikawa, C. L.; Weller, S.; Andresen, T. L.; Hansen, A. E.; Autzen, A. A. A.
10.1101/2023.03.23.533909 — cancer biology — Posted on 2023-03-24
1064 Endogenous viral elements constitute a complementary source of antigens for personalized cancer immunotherapy
Garde, C.; Pavlidis, M. A.; Garces, P.; Lange, E. J.; Ramarathinam, S. H.; Sokac, M.; Pandey, K.; Faridi, P.; Ahrenfeldt, J.; Chung, S.; Friis, S.; Kleine-Kohlbrecher, D.; Birkbak, N. J.; Kringelum, J. V.; Rono, B.; Purcell, A. W.; Trolle, T.
10.1101/2023.03.23.533908 — cancer biology — Posted on 2023-03-24
1066 Ensemble-GNN: federated ensemble learning with graph neural networks for disease module discovery and classification
Pfeifer, B.; Chereda, H.; Martin, R.; Saranti, A.; Angerschmid, A.; Clemens, S.; Hauschild, A.-C.; Beissbarth, T.; Holzinger, A.; Heider, D.
10.1101/2023.03.22.533772 — bioinformatics — Posted on 2023-03-24
1069 Capturing Spatiotemporal Signaling Patterns in Cellular Data with Geometric Scattering Trajectory Homology
Bhaskar, D.; Moore, J. L.; Gao, F.; Rieck, B.; Khasawneh, F.; Munch, E.; Greco, V.; Krishnaswamy, S.
10.1101/2023.03.22.533807 — bioinformatics — Posted on 2023-03-24
1072 Memory Th1 cells modulate heterologous diseases through innate function
Rakebrandt, N.; Yassini, N.; Kolz, A.; Schorer, M.; Lambert, K.; Rauld, C.; Balazs, Z.; Krauthammer, M.; Carballido, J.; Peters, A.; Joller, N.
10.1101/2023.03.22.533799 — immunology — Posted on 2023-03-24
1073 Live cell imaging of ATP levels reveals metabolic compartmentalization within motoneurons and early metabolic changes in FUS ALS motoneurons.
Zimyanin, V.; Pielka, A.-M.; Glass, H.; Japtok, J.; Martin, M.; Deussen, A.; Szewczyk, B.; Deppmann, C. D.; Zunder, E.; Andersen, P. M.; Boeckers, T.; Sterneckert, J.; Redemann, S.; Storch, A.; Hermann, A.
10.1101/2023.03.22.533787 — neuroscience — Posted on 2023-03-24
1075 Representations of carbon dioxide in the mosquito antennal lobe
Goyal, S.; Singh, P.; Gupta, M.; Gupta, S.; Singh, S. S.; Gupta, A. k.; Gupta, N.
10.1101/2023.03.22.533824 — neuroscience — Posted on 2023-03-24
1076 Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to progressive synaptic dysfunction in human iPSC-derived motor neurons
Lepine, S.; Nauleau-Javaudin, A.; Deneault, E.; Chen, C. X.- Q.; Abdian, N.; Franco-Flores, A. K.; Haghi, G.; Castellanos-Montiel, M. J.; Maussion, G.; Chaineau, M.; Durcan, T. M.
10.1101/2023.03.22.533562 — neuroscience — Posted on 2023-03-24
1077 BIBSNet: A Deep Learning Baby Image Brain Segmentation Network for MRI Scans
Hendrickson, T. J.; Reiners, P.; Moore, L. A.; Perrone, A. J.; Alexopoulos, D.; Lee, E. G.; Styner, M.; Kardan, O.; Chamberlain, T. A.; Mummaneni, A.; Caldas, H. A.; Bower, B.; Stoyell, S.; Martin, T.; Sung, S.; Fair, E.; Uriarte-Lopez, J.; Rueter, A. R.; Rosenberg, M. D.; Smyser, C. D.; Elison, J. T.; Graham, A.; Fair, D. A.; Feczko, E.
10.1101/2023.03.22.533696 — neuroscience — Posted on 2023-03-24
1079 Latent transcriptional programs reveal histology-encoded tumor features spanning tissue origins
Hieromnimon, H. M.; Dolezal, J.; Doytcheva, K.; Howard, F. M.; Kochanny, S.; Zhang, Z.; Grossman, R. L.; Tanager, K.; Wang, C.; Kather, J. N.; Izumchenko, E.; Cipriani, N. A.; Fertig, E. J.; Pearson, A. T.; Riesenfeld, S. J.
10.1101/2023.03.22.533810 — cancer biology — Posted on 2023-03-24
1081 Adaptive therapy for ovarian cancer: An integrated approach to PARP inhibitor scheduling
Strobl, M.; Martin, A.; West, J.; Gallaher, J.; Robertson-Tessi, M.; Gatenby, R.; Wenham, R.; Maini, P.; Damaghi, M.; Anderson, A. R. A.
10.1101/2023.03.22.533721 — cancer biology — Posted on 2023-03-24
1085 Assessing motile cilia coverage and beat frequency in mammalian in-vitro cell culture tissues
Fradique, R.; Causa, E.; Delahousse, C.; Kotar, J.; Pinte, L.; Vallier, L.; Vila-Gonzalez, M.; Cicuta, P.
10.1101/2023.03.22.533861 — biophysics — Posted on 2023-03-24
1087 A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway
The Proteostasis Consortium, ; Elsasser, S.; Elia, L. P.; Morimoto, R. I.; Powers, E. T.; Finley, D.; Costa, B.; Budron, M.; Tokuno, Z.; Wang, S.; Iyer, R. G.; Barth, B.; Mockler, E.; Finkbeiner, S.; Gestwicki, J. E.; Richardson, R. A. K.; Stoeger, T.; Tan, E. P.; Xiao, Q.; Cole, C. M.; Massey, L. A.; Garza, D.; Kelly, J. W.; Rainbolt, T. K.; Chou, C.-C.; Masto, V. B.; Frydman, J.; Nixon, R. A.
10.1101/2023.03.22.533675 — bioinformatics — Posted on 2023-03-24
1089 Dimension-agnostic and granularity-based spatially variable gene identification
Wang, J.; Li, J.; Kramer, S. T.; Su, L.; Chang, Y.; Xu, C.; Ma, Q.; Xu, D.
10.1101/2023.03.21.533713 — bioinformatics — Posted on 2023-03-24
1091 An explainable deep learning classifier of bovine mastitis based on whole genome sequence data - circumventing the p>>>n problem
Kotlarz, K.; Mielczarek, M.; Biecek, P.; Wojdak-Maksymiec, K.; Suchocki, T.; Topolski, P.; Jagusiak, W.; Szyda, J.
10.1101/2023.03.23.533903 — bioinformatics — Posted on 2023-03-24
1093 Chromosome-aware phylogenomics of Assassin Bugs (Hemiptera: Reduvioidea) elucidates ancient gene conflict
Knyshov, A.; Gordon, E. R. L.; Masonick, P. K.; Castillo, S.; Forero, D.; Hoey-Chamberlain, R.; Hwang, W. S.; Johnson, K. P.; Lemmon, A. R.; Moriarty Lemmon, E.; Standring, S.; Zhang, J.; Weirauch, C.
10.1101/2023.03.22.533714 — genomics — Posted on 2023-03-24
1096 Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China
Baker, M.; Zhang, X.; Maciel-Guerra, A.; Babaarslan, K.; Dong, Y.; Wang, W.; Hu, Y.; Renney, D.; Liu, L.; Li, H.; Tong, Z.; Pearcy, N.; Zhang, M.; Geng, Y.; Zhao, L.; Hao, Z.; Chen, J.; Peng, Z.; Li, F.; Dottorini, T.
10.1101/2023.03.22.533846 — genomics — Posted on 2023-03-24
1097 Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin
Price, T. R.; Stapleton, D. S.; Schueler, K. L.; Norris, M. K.; Parks, B. W.; Yandell, B. S.; Churchill, G. A.; Holland, W. L.; Keller, M. P.; Attie, A.
10.1101/2023.03.23.533902 — genetics — Posted on 2023-03-24
1100 Knockdown of Atg1 or Atg18 in adult adipocytes impairs lipophagy and reduces lifespan of fruit flies (Drosophila melanogaster)
Zhu, C.; Bierlein, M.; Charles, J.; Polisuk-Balfour, T.; Bretscher, H.; Rice, M.; Zvonar, J.; Pohl, D.; Winslow, L.; Wasie, B.; Deurloo, S.; Van Wert, J.; Williams, B.; Ankney, G.; Harmon, Z.; Dann, E.; Azuz, A.; Guzman-Vargas, A.; Kuhns, E.; Neufeld, T. P.; O'Connor, M. B.; Amissah, F.
10.1101/2023.03.22.533865 — genetics — Posted on 2023-03-24
1104 Are increasing honey bee colony losses attributed to Varroa destructor in New Zealand driven by miticide resistance?
McGruddy, R. A.; Bulgarella, M.; Felden, A.; Baty, J. W.; Haywood, J.; Stahlmann-Brown, P.; Lester, P. J.
10.1101/2023.03.22.533871 — ecology — Posted on 2023-03-24
1105 Is adaptive foraging adaptive? A resource-consumer eco-evolutionary model.
Ledru, L.; Garnier, J.; Guillot, O.; Faou, E.; Nous, C.; Ibanez, S.
10.1101/2023.03.22.533765 — ecology — Posted on 2023-03-24
1108 Cell targeting and immunostimulatory properties of a novel Fcγ-receptor independent agonistic anti-CD40 antibody in rhesus macaques
Yan, X.; Ols, S.; Arcoverde Cerveira, R.; Lenart, K.; Hellgren, F.; Ye, K.; Cagigi, A.; Buggert, M.; Nimmerjahn, F.; Falkesgaard Hojen, J.; Parera, D.; Pessara, U.; Fischer, S.; Lore, K.
10.1101/2023.03.22.533762 — immunology — Posted on 2023-03-24
1109 Molecular heterogeneity of C. elegans glia across sexes
Purice, M. D.; Quitevis, E. J. A.; Manning, R. S.; Severs, L. J.; Tran, N. T.; Sorrentino, V.; Setty, M.; Singhvi, A.
10.1101/2023.03.21.533668 — neuroscience — Posted on 2023-03-24
1112 Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons
Saito-Diaz, K.; Dietrich, P.; Wu, H.-F.; Sun, X.; Patel, A. J.; Wzientek, C. G.; Prudden, A. R.; Boons, G.-J.; Chen, S.; Studer, L.; Xu, B.; Dragatsis, I.; Zeltner, N.
10.1101/2023.03.22.533831 — neuroscience — Posted on 2023-03-24
1113 Differential effects of the stress peptides PACAP and CRF on sleep architecture in mice
Foilb, A. R.; Taylor-Yeremeeva, E. M.; Fritsch, E. L.; Ravichandran, C.; Lezak, K. R.; Missig, G.; McCullough, K. M.; Carlezon, W. A.
10.1101/2023.03.22.533872 — neuroscience — Posted on 2023-03-24
1114 Towards a Foundation Model of the Mouse Visual Cortex
Wang, E. Y.; Fahey, P. G.; Ponder, K.; Ding, Z.; Change, A.; Muhammad, T.; Patel, S.; Ding, Z.; Tran, D. T.; Fu, J.; Papadopoulos, S.; Franke, K.; Ecker, A. S.; Reimer, J.; Pitkow, X.; Sinz, F. H.; Tolias, A. S.
10.1101/2023.03.21.533548 — neuroscience — Posted on 2023-03-24
1115 Spinal control of locomotion before and after spinal cord injury
Danner, S. M.; Shepard, C. T.; Hainline, C.; Shevtsova, N. A.; Rybak, I. A.; Magnuson, D. S. K.
10.1101/2023.03.22.533794 — neuroscience — Posted on 2023-03-24
1118 Time-dependent neural arbitration between cue associative and episodic fear memories
Cortese, A.; Ohata, R.; Alemany, M.; Kitagawa, N.; Imamizu, H.; Koizumi, A.
10.1101/2023.03.22.533726 — neuroscience — Posted on 2023-03-24
1120 Microbial short-chain fatty acids regulate drug seeking and transcriptional control in a model of cocaine seeking
Meckel, K. R.; Simpson, S.; Godino, A.; Peck, E. G.; George, O.; Calipari, E. S.; Hofford, R. S.; Kiraly, D.
10.1101/2023.03.22.533834 — neuroscience — Posted on 2023-03-24
1121 Integrating EM and Patch-seq data: Synaptic connectivity and target specificity of predicted Sst transcriptomic types
Gamlin, C. R.; Schneider-Mizell, C. M.; Mallory, M.; Elabbady, L.; Gouwens, N.; Williams, G.; Mukora, A.; Dalley, R.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Kapner, D.; Kinn, S.; Mahalingam, G.; Seshamani, S.; Takeno, M.; Torres, R.; Yin, W.; Nicovich, P. R.; Bae, J. A.; Castro, M. A.; Dorkenwald, S.; Halageri, A.; Jia, Z.; Jordan, C.; Kemnitz, N.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Silversmith, W.; Turner, N. L.; Wong, W.; Wu, J.; Yu, S.-c.; Berg, J.; Jarsky, T.; Lee, B.; Seung, H. S.; Zeng, H.; Reid, R. C
10.1101/2023.03.22.533857 — neuroscience — Posted on 2023-03-24
1122 A cortical surface template for human neuroscience
Feilong, M.; Jiahui, G.; Gobbini, M. I.; Haxby, J. V.
10.1101/2023.03.21.533686 — neuroscience — Posted on 2023-03-24
1126 Role of membrane estrogen receptor alpha on the positive feedback of estrogens on LH secretion
Faure, M. C.; Corona, R.; de Bournonville, C.; Lenfant, F.; Foidart, J.-M.; Cornil, C. A.
10.1101/2023.03.22.533736 — neuroscience — Posted on 2023-03-24
1128 Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results
Baron, C.; Cherkaoui, S.; Therrien-Laperriere, S.; Ilboudo, Y.; Poujol, R.; Mehanna, P.; Garrett, M. E.; Telen, M. J.; Ashley-Koch, A. E.; Bartolucci, P.; Rioux, J. D.; Lettre, G.; Des Rosiers, C.; Ruiz, M.; Hussin, J.
10.1101/2023.03.22.533869 — systems biology — Posted on 2023-03-24
1132 Fluorescent Sensors for Imaging Interstitial Calcium
Valiente-Gabioud, A. A.; Suner, I. G.; Idziak, A.; Fabritius, A.; Angibaud, J.; Basquin, J.; Nagerl, U. V.; Singh, S. P.; Griesbeck, O.
10.1101/2023.03.23.533956 — physiology — Posted on 2023-03-24
1134 Cell-type specific EWAS identifies genes involved in HIV pathogenesis andoncogenesis among people with chronic HIV infection
Zhang, X.; Hu, Y.; Vandenhoudt, R. E.; Yan, C.; Marconi, V. C.; Cohen, M. H.; Justice, A. C.; Aouizerat, B. E.; Xu, K.
10.1101/2023.03.21.533691 — cancer biology — Posted on 2023-03-24
1135 Killing the enemy or making it your ally? The effects of thiostrepton on tumor associated macrophages
Pereira-Martins, D. A.; Hilberink, J.; Weinhauser, I.; Rego, E.; Huls, G.; Schuringa, J. J.
10.1101/2023.03.23.533899 — cancer biology — Posted on 2023-03-24
1136 The new signaling pathway ERK5/TP53INP2 sensitizes cancer cells to death-receptor agonists and Natural Killer cells
Espinosa-Gil, S.; Ivanova, S.; Alari-Pahissa, E.; Denizli, M.; Villafranca-Magdalena, B.; Vinas-Casas, M.; Bolinaga-Ayala, I.; Gamez-Garcia, A.; Colas, E.; Lopez-Botet, M.; Zorzano, A.; Lizcano, J. M.
10.1101/2023.03.22.533738 — cancer biology — Posted on 2023-03-24
1137 Recycling of Bacterial RNA Polymerase by the Swi2/Snf2 ATPase RapA
Inlow, K.; Tenenbaum, D.; Friedman, L. J.; Kondev, J.; Gelles, J.
10.1101/2023.03.22.533849 — biophysics — Posted on 2023-03-24
1139 Integration of taxonomic signals from MAGs and contigs improves read annotation and taxonomic profiling of metagenomes
Hauptfeld, E.; Pappas, N.; van Iwaarden, S.; Snoek, B. L.; Aldas-Vargas, A.; Dutilh, B. E.; von Meijenfeldt, F. B.
10.1101/2023.03.22.533753 — bioinformatics — Posted on 2023-03-24
1143 Energy-Saving Pretreatments Affect Pelagic Sargassum Composition and DNA Metabarcoding Analysis Reveals the Microbial Community Involved in Methane Yield
Salgado-Hernandez, E.; Alvarado-Lassman, A.; Martinez-Hernandez, S.; Velazquez-Fernandez, J. B.; Dorantes-Acosta, A. E.; Rosas-Mendoza, E. S.; Ortiz-Ceballos, A. I.
10.1101/2023.03.21.533673 — bioengineering — Posted on 2023-03-24
1145 Manifold Learning Enables Interpretable Analysis of Raman Spectra from Extracellular Vesicle and Other Mixtures
Kazemzadeh, M.; Martinez-Calderon, M.; Otupiri, R.; Artuyants, A.; Lowe, M.; Ning, X.; Reategui, E.; Schultz, Z. D.; Xu, W.; Blenkiron, C.; Chamley, L. W.; Broderick, N. G. R.; Hisey, C. L.
10.1101/2023.03.20.533481 — bioengineering — Posted on 2023-03-24
1148 Duckweed evolution: from land back to water
Fang, Y.; Tian, X.; Jin, Y.; Du, A.; Ding, Y.; Liao, Z.; He, K.; Zhao, Y.; Guo, L.; Xiao, Y.; Xu, Y.; Chen, S.; Che, Y.; Tan, L.; Wang, S.; Li, J.; Yi, Z.; Chen, L.; Zhao, L.; Zhang, F.; Li, G.; Li, J.; Xiong, Q.; Zhang, Y.; Zhang, Q.; Cao, X. H.; Zhao, H.
10.1101/2023.03.22.533731 — evolutionary biology — Posted on 2023-03-24
1151 Effect of egg production dynamics on the functional response of parasitoids
Aguirre, M. B.; Logarzo, G.; Triapitsyn, S.; Diaz-Soltero, H.; Hight, S.; Bruzzone, O.
10.1101/2023.03.22.533781 — ecology — Posted on 2023-03-24
1156 Golgi organization is a determinant of stem cell function in the small intestine
Scharaw, S.; Sola Carvajal, A.; Belevich, I.; Webb, A. T.; Das, S.; Andersson, S.; Pentinmikko, N.; Villablanca, E. J.; Goldenring, J. R.; Jokitalo, E.; Coffey, R. J.; Katajisto, P.
10.1101/2023.03.23.533814 — cell biology — Posted on 2023-03-24
1157 De novo serine biosynthesis is protective in mitochondrial disease
Jackson, C. B.; Marmyleva, A.; Awadhpersad, R.; Monteuuis, G.; Mito, T.; Zamboni, N.; Tatsuta, T.; Vincent, A. E.; Wang, L.; Langer, T.; Carroll, C. J.; Suomalainen-Wartiovaara, A.
10.1101/2023.03.23.533952 — cell biology — Posted on 2023-03-24
1158 Single-cell mRNA-regulation analysis reveals cell type-specific mechanisms of type 2 diabetes
Martinez-Lopez, J.; Lindqvist, A.; Lopez-Pascual, A.; Chen, P.; Shcherbina, L.; Chriett, S.; Skene, N. G.; Prasad, R. B.; Lancien, M.; Johnson, P. F.; Eliasson, P.; Louvet, C.; Munoz-Manchado, A. B.; Sandberg, R.; Hjerling-Leffler, J.; Wierup, N.
10.1101/2023.03.23.533985 — cell biology — Posted on 2023-03-24
1160 HCC-1 accelerates atherosclerosis by inducing endothelial cells and macrophages pyroptosis and serves as an early diagnostic biomarker
Bu, F.; Wang, J.; Zhang, Q.; Lin, X.; Zhang, R.; Bai, L. H.; Chen, J.; Hua, Y.; Huang, M.; Huang, Y.; Wang, H.; Hu, X.-M.; Zheng, L.; Wang, Q.
10.1101/2023.03.22.533883 — cell biology — Posted on 2023-03-24
1162 Proximity mapping of desmosomes reveals a striking shift in their molecular neighbourhood associated with maturation
Fuelle, J. B.; de Almeida, R. A.; Lawless, C.; Yanes, B.; Lane, E. B.; Garrod, D. R.; Ballestrem, C.
10.1101/2023.03.24.534085 — cell biology — Posted on 2023-03-24
1163 Visualization of translation reorganization upon persistent collision stress in mammalian cells
Fedry, J.; Silva, J.; Vanevic, M.; Fronik, S.; Mechulam, Y.; Schmitt, E.; des Georges, A.; Faller, W.; Förster, F.
10.1101/2023.03.23.533914 — cell biology — Posted on 2023-03-24
1164 ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
Nixon-Abell, J.; Ruggeri, F. S.; Qamar, S.; Herling, T. W.; Czekalska, M. A.; Shen, Y.; Wang, G.; King, C.; Fernandopulle, M. S.; Sneideris, T.; Watson, J. L.; Pillai, V. V.; Meadows, W.; Henderson, J.; Chambers, J. E.; Wagstaff, J. L.; Williams, S. H.; Coyle, H.; Lu, Y.; Zhang, S.; Marciniak, S. J.; Freund, S. M.; Derivery, E.; Ward, M. E.; Vendruscolo, M.; Knowles, T. P.; St George Hyslop, P.
10.1101/2023.03.22.533832 — cell biology — Posted on 2023-03-24
1165 Ex vivo primary liver sections recapitulate disease phenotype and therapeutic rescue for liver monogenic diseases
Perocheau, D. P.; Baruteau, J.; Gurung, S.; Touramanidou, L.; Duff, C.; Sharma, G.; Sebire, N.; Finn, P.; Cavedon, A.; Siddiqui, S.; Rice, L.; Martini, P.; Frassetto, A.
10.1101/2023.03.23.533840 — cell biology — Posted on 2023-03-24
1167 TAp73 regulates mitochondrial dynamics and multiciliated cell homeostasis through an OPA1 axis
Buckley, N.; Craxton, A.; Sun, X.-M.; Panatta, E.; Pinon, L.; Llodra, J.; Morone, N.; Amelio, I.; Melino, G.; Martins, L. M.; MacFarlane, M.
10.1101/2023.03.23.533672 — cell biology — Posted on 2023-03-24
1168 Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy
Liffner, B.; Cepeda Diaz, A. K.; Blauwkamp, J.; Anaguano, D.; Frolich, S.; Muralidharan, V.; Wilson, D. W.; Dvorin, J.; Absalon, S.
10.1101/2023.03.22.533773 — cell biology — Posted on 2023-03-24
1170 A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8
Rodriguez-Rodriguez, B. A.; Ciabattoni, G.; Duerr, R.; Valero-Jimenez, A. M.; Yeung, S. T.; Crosse, K. M.; Schinlever, A.; Bernard-Raichon, L.; Rodriguez-Galvan, J. J.; McGrath, M.; Vashee, S.; Xue, Y.; Loomis, C.; Khanna, K. M.; Cadwell, K. H.; Desvignes, L.; Frieman, M.; Ortigoza, M. B.; Dittmann, M.
10.1101/2022.10.04.510658 — microbiology — Posted on 2023-03-24
1173 Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics
Williams, C. M.; Poore, H.; Tanksley, P. T.; Kweon, H.; Courchesne-Krak, N. S.; Londono-Correa, D.; Mallard, T. T.; Barr, P.; Koellinger, P. D.; Waldman, I.; Sanchez-Roige, S.; Harden, K. P.; Palmer, A. A.; Dick, D. D.; Linner, R. K.
10.1101/2023.03.21.533641 — genetics — Posted on 2023-03-24
1176 Inferring invasion determinants with mechanistic models and multitype samples
Saubin, M.; Coville, J.; Xhaard, C.; Frey, P.; Soubeyrand, S.; Halkett, F.; Fabre, F.
10.1101/2023.03.21.533642 — evolutionary biology — Posted on 2023-03-24
1178 Seed functional ecology in Brazilian rock outcrop vegetation: an integrative synthesis
Ordonez-Parra, C. A.; Medeiros, N. F.; Dayrell, R. L. C.; Le Stradic, S.; Negreiros, D.; Cornelissen, T.; Silveira, F. A. O.
10.1101/2023.03.21.533674 — ecology — Posted on 2023-03-24
1182 Unraveling Chamber-specific Differences in Intercalated Disc Ultrastructure and Molecular Organization and Their Impact on Cardiac Conduction
Struckman, H. L.; Moise, N.; King, D. R.; Soltisz, A. M.; Buxton, A.; Dunlap, I.; Chen, Z.; Radwanski, P. B.; Weinberg, S. H.; Veeraraghavan, R.
10.1101/2023.02.13.528369 — physiology — Posted on 2023-03-24
1184 Determining the neuronal ensembles underlying sex-specific social impairments following adolescent intermittent ethanol exposure
Towner, T. T.; Goyden, M. A.; Coleman, H. J.; Drumm, M. K.; Ritchie, I. P.; Lieb, K. R.; Varlinskaya, E. I.; Werner, D. F.
10.1101/2023.03.21.533653 — animal behavior and cognition — Posted on 2023-03-24
1186 Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis
Mastropasqua, F.; Oksanen, M.; Soldini, C.; Alatar, S.; Arora, A.; Ballarino, R.; Molinari, M.; Agostini, F.; Poulet, A.; Watts, M. E.; Rabkina, I.; Becker, M.; Li, D.; Anderlid, B.-M.; Isaksson, J.; Remnelius, K. L.; Moslem, M.; Jacob, Y.; Falk, A.; Crosetto, N.; Bienko, M.; Santini, E.; Borgkvist, A.; Bölte, S.; Tammimies, K.
10.1101/2022.09.14.507275 — neuroscience — Posted on 2023-03-24
1187 Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever
Gravett, M. S. C.; Klebl, D. P.; Harlen, O. G.; Read, D. J.; Harris, S. A.; Muench, S. P.; Peckham, M.
10.1101/2023.03.19.533260 — biophysics — Posted on 2023-03-24
1189 Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs
Bagato, O.; Balkema-Buschmann, A.; Todt, D.; Weber, S.; Goemer, A.; Qu, B.; Miskey, C.; Mettenleiter, T. C.; Finke, S.; Brown, R. J. P.; Breithaupt, A.; Ushakov, D. S.
10.1101/2023.03.22.533759 — immunology — Posted on 2023-03-24
1191 CT Image-Derived Fluctuations in Total Curvature Characterize Aortic Disease Evolution and Clinical Outcomes
Khabaz, K.; Sankary, S.; Yuan, K.; Pugar, J.; Kim, J.; Kang, J.; Nguyen, N.; Cao, K.; Pierce, N.; Lee, C. J.; Milner, R.; Kindlmann, G.; Pocivavsek, L.
10.1101/2022.09.19.508582 — bioengineering — Posted on 2023-03-24
1192 Emergent remote stress-focusing drive submucosal collagen-fiber remodeling in intestinal anastomotic surgery
Fleischer, B.; Nguyen, N.; Pal, A.; Khabaz, K.; Tsamis, A.; Efrati, E.; Witten, T.; Alverdy, J.; Pocivavsek, L.
10.1101/2022.10.31.514540 — bioengineering — Posted on 2023-03-24
1193 An extended Tudor domain within Vreteno interconnects Gtsf1L and Ago3 for piRNA biogenesis in Bombyx mori
Bronkhorst, A. W.; Luck, K.; Stelzl, L.; Ketting, R. F.; Sadouki, S.; Moeckel, M.; Ruegenberg, S.; Lee, C.; de Jesus Domingues, A.; Sumiyoshi, T.; Siomi, M. C.
10.1101/2023.03.23.533951 — molecular biology — Posted on 2023-03-24
1196 Hypoxia-induced activation of NDR2 underlies brain metastases from Non-Small Cell Lung Cancer
Levallet, J.; Biojout, T.; Bazille, C.; Douyere, M.; Dubois, F.; Leite Ferreira, D.; Taylor, J.; Teulier, S.; Toutain, J.; Bernaudin, M.; Valable, S.; Bergot, E.; Levallet, G.
10.1101/2023.03.20.533395 — cancer biology — Posted on 2023-03-24
1197 A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Andradi-Brown, C.; Wichers-Misterek, J. S.; von Thien, H.; Höppner, Y. D.; Scholz, J. A. M.; Smedegaard Hansson, H.; Filtenborg Hocke, E.; Gilberger, T. W.; Duffy, M.; Lavstsen, T.; Baum, J.; Otto, T. D.; Cunnington, A. J.; Bachmann, A.
10.1101/2023.03.21.533599 — bioinformatics — Posted on 2023-03-24
1199 Her6 and Prox1 are novel regulators of photoreceptor regeneration in the zebrafish retina
Veen, K.; Krylov, A.; Yu, S.; He, J.; Boyd, P.; Hyde, D.; Mantamadiotis, T.; Cheng, L.; Jusuf, P. R.
10.1101/2023.03.20.532714 — genetics — Posted on 2023-03-24
1201 Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis
Sahu, B. S.; Razzoli, M.; McGonigle, S.; Pallais, J. P.; Nguyen, M.; Sadahiro, M.; Jiang, C.; Lin, W.-J.; Kelley, K.; Rodriguez, P.; Mansk, R.; Cero, C.; Caviola, G.; Palanza, P.; Rao, L.; Beetch, M.; Alejandro, E.; Sham, Y.; Frontini, A.; Salton, S.; Bartolomucci, A.
10.1101/2023.03.23.532619 — physiology — Posted on 2023-03-24
1203 Group A Streptococcus strains causing meningitis without distinct invasive phenotype
Marquardt, L.; Andreoni, F.; Boumasmoud, M.; Schweizer, T. A.; Heuberger, D.; Parietti, E.; Epprecht, J.; Mattle, D.; Raez, A.; Marques-Maggio, E.; Schuepbach, R.; Hasse, B. K.; Mairpady Shambat, S.; Brugger, S. D.; Zinkernagel, A.
10.1101/2023.03.22.533757 — microbiology — Posted on 2023-03-24
1204 Does the brain care about averages? A simple test.
Tlaie, A.; Shapcott, K. A.; van der Plas, T.; Rowland, J. M.; Lees, R.; Keeling, J.; Packer, A.; Tiesinga, P.; Schölvinck, M.; Havenith, M. N.
10.1101/2021.11.28.469673 — neuroscience — Posted on 2023-03-24
1206 Deterministic evolution and stringent selection during pre-neoplasia
Karlsson, K.; Przybilla, M. J.; Kotler, E.; Khan, A.; Xu, H.; Karagyozova, K.; Sockell, A.; Wong, W. H.; Liu, K.; Mah, A.; Lo, Y.-H.; Lu, B.; Houlahan, K. E.; Ma, Z.; Suarez, C. J.; Barnes, C. P.; Kuo, C. J.; Curtis, C.
10.1101/2022.04.09.487529 — cancer biology — Posted on 2023-03-24
1208 Meningeal origins and dynamics of perivascular fibroblast development on the mouse cerebral vasculature
Jones, H. E.; Coelho-Santos, V.; Bonney, S. K.; Abrams, K. A.; Shih, A. Y.; Siegenthaler, J. A.
10.1101/2023.03.23.533982 — developmental biology — Posted on 2023-03-24
1211 Mind of a dauer: Comparative connectomics reveals developmental plasticity
Yim, H.; Choe, D. T.; Bae, J. A.; Kang, H.-M.; Nguyen, K. C. Q.; Choi, M.-k.; Ahn, S.; Bahn, S.-k.; Yang, H.; Hall, D. H.; Kim, J. S.; Lee, J.
10.1101/2023.03.23.533915 — neuroscience — Posted on 2023-03-23
1214 A novel Fis1 inhibiting peptide reverses diabetic endothelial dysfunction in human resistance arteries
Nolden, K. A.; Kakarla, M.; Egner, J. M.; Wang, J.; Harwig, M. C.; Puppala, V. K.; Hofeld, B. C.; Arnold, L. A.; Trykall, D. Z.; Peterson, F. C.; Roberts, M. L.; Jensen, D. M.; Hill, R. B.; Widlansky, M. E.
10.1101/2020.11.16.385054 — physiology — Posted on 2023-03-23
1217 A comprehensive map of hotspots of de novo telomere addition in Saccharomyces cerevisiae
Ngo, K.; Gittens, T. H.; Gonzalez, D. I.; Hatmaker, E. A.; Plotkin, S.; Engle, M.; Friedman, G. A.; Goldin, M.; Hoerr, R. E.; Eichman, B. F.; Rokas, A.; Benton, M. L.; Friedman, K. L.
10.1101/2023.03.20.533556 — genetics — Posted on 2023-03-23
1218 Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo
Zhang, H.; Kelly, K.; Lee, J.; Echeverria, D.; Cooper, D.; Panwala, R.; Chen, Z.; Gaston, N.; Newby, G. A.; Xie, J.; Liu, D. R.; Gao, G.; Wolfe, S. A.; Khvorova, A.; Watts, J. K.; Sontheimer, E. J.
10.1101/2023.03.20.533459 — molecular biology — Posted on 2023-03-23
1227 Microbially-derived indole-3-acetate alleviates diet induced steatosis and inflammation in mice
Ding, Y.; Yanagi, K.; Yang, F.; Callaway, E.; Cheng, C.; Hensel, M.; Menon, R.; Alaniz, R.; Lee, K.; Jayaraman, A.
10.1101/2023.03.21.533660 — cell biology — Posted on 2023-03-23
1228 Plasmodium exoerythrocytic parasites redirect trafficking of human proteins to the parasitophorous vacuole
Calla, J.; Mittal, N.; LaMonte, G.; Liffner, B.; Godinez-Macias, K.; Carolino, K.; Walker, G. T.; Zou, B. Y.; Paytas, E.; Guerra, L.; Tong-Rios, C.; Campo, B.; Vinetz, J. M.; Gamboa, D.; Raffatellu, M.; Absalon, S.; Winzeler, E.
10.1101/2022.11.22.517223 — cell biology — Posted on 2023-03-23
1233 Ensemble remodeling supports memory-updating
Mau, W.; Baggetta, A. M.; Dong, Z.; Sweis, B. M.; Morales-Rodriguez, D.; Pennington, Z. T.; Francisco, T.; Freedman, D. J.; Baxter, M. G.; Shuman, T.; Cai, D. J.
10.1101/2022.06.02.494530 — neuroscience — Posted on 2023-03-23
1235 Target of selective auditory attention can be robustly followed with MEG
Kurmanaviciute, D.; Kataja, H.; Jas, M.; Valila, A.; Parkkonen, L.
10.1101/588491 — neuroscience — Posted on 2023-03-23
1236 Using interactive platforms to encode, manage and explore immune-related adverse outcome pathways
Mazein, A.; Shoaib, M.; Alb, M.; Sakellariou, C.; Sommer, C.; Sewald, K.; Reiche, K.; Gogesch, P.; Roser, L. A.; Ortega Iannazzo, S.; Sheth, S.; Schiffmann, S.; Waibler, Z.; Neuhaus, V.; Dehmel, S.; Satagopam, V.; Schneider, R.; Ostaszewski, M.; Gu, W.
10.1101/2023.03.21.533620 — systems biology — Posted on 2023-03-23
1237 standard-GEM: standardization of open-source genome-scale metabolic models
Anton, M.; Almaas, E.; Benfeitas, R.; Benito-Vaquerizo, S.; Blank, L. M.; Dräger, A.; Hancock, J. M.; Kittikunapong, C.; König, M.; Li, F.; Liebal, U. W.; Lu, H.; Ma, H.; Mahadevan, R.; Mardinoglu, A.; Nielsen, J.; Nogales, J.; Pagni, M.; Papin, J. A.; Patil, K. R.; Price, N. D.; Robinson, J. L.; Sanchez, B. J.; Suarez Diez, M.; Sulheim, S.; Svensson, L. T.; Teusink, B.; Vongsangnak, W.; Wang, H.; Zeidan, A. A.; Kerkhoven, E. J.
10.1101/2023.03.21.512712 — systems biology — Posted on 2023-03-23
1239 Immature leaves are the dominant volatile sensing organs of maize
Wang, L.; Jaeggi, S.; Walthert, M.; Waterman, J. M.; Cofer, T. M.; Erb, M.
10.1101/2023.01.12.523648 — plant biology — Posted on 2023-03-23
1240 Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens
Yao, M.; Preall, J.; Yeh, J.; Pappin, D.; Cifani, P.; Zhao, Y.; Shen, S.; Moresco, P.; He, B.; Patel, H.; Habowski, A.; King, D.; Raphael, K.; Rishi, A.; Sejpal, D.; Weiss, M.; Tuveson, D.; Fearon, D.
10.1101/2023.03.20.533453 — cancer biology — Posted on 2023-03-23
1242 Inter-organelle crosstalk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress
Kuna, R. S.; Kumar, A.; Wessendorf-Rodriguez, K. A.; Galvez, H.; Green, C. R.; McGregor, G. H.; Cordes, T.; Shaw, R. J.; Svensson, R. U.; Metallo, C.
10.1101/2022.09.24.509326 — biochemistry — Posted on 2023-03-23
1243 Phosphoregulation of the Rad51 auxiliary factor Swi5-Sfr1
Liang, P.; Lister, K. P.; Yates, L. A.; Argunhan, B.; Zhang, X.
10.1101/2023.03.23.533938 — biochemistry — Posted on 2023-03-23
1248 An experimental framework to assess biomolecular condensates in bacteria
Hoang, Y.; Azaldegui, C. A.; Ghalmi, M.; Biteen, J. S.; Vecchiarelli, A. G.
10.1101/2023.03.22.533878 — microbiology — Posted on 2023-03-23
1250 Brain functional characterization of response-code conflict in dual-tasking and its modulation by age
Oliveros, L. K. P.; Cieslik, E. C.; Pieczykolan, A.; Pläschke, R. N.; Eickhoff, S. B.; Langner, R.
10.1101/2023.03.21.533669 — neuroscience — Posted on 2023-03-23
1252 Modeling transcriptional regulation of the cell cycle using a novel cybernetic-inspired approach
Raja, R.; Khanum, S.; Aboulmouna, L.; Maurya, M. R.; Gupta, S.; Subramaniam, S.; Ramkrishna, D.
10.1101/2023.03.21.533676 — systems biology — Posted on 2023-03-23
1256 Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stresses
Wang, J.; Wen, Y.; Zhao, W.; Zhang, Y.; Lin, F.; Ouyang, C.; Wang, H.; Yao, L.; Ma, H.; Zhuo, Y.; Huang, H.; Shi, X.; Feng, L.; Lin, D.; Jiang, B.; Li, Q.
10.1101/2023.03.23.533947 — biochemistry — Posted on 2023-03-23
1260 A comprehensive map of hotspots of de novo telomere addition in Saccharomyces cerevisiae
Ngo, K.; Gittens, T. H.; Gonzalez, D. I.; Hatmaker, E. A.; Plotkin, S.; Engle, M.; Friedman, G. A.; Goldin, M.; Hoerr, R. E.; Eichman, B. F.; Rokas, A.; Benton, M. L.; Friedman, K. L.
10.1101/2023.03.20.533556 — genetics — Posted on 2023-03-23
1261 Understanding the Divergent Evolution and Epidemiology of H3N8 Influenza Viruses in Dogs and Horses
Wasik, B. R.; Rothschild, E.; Voorhees, I. E.; Reedy, S. E.; Murcia, P. R.; Pusterla, N.; Chambers, T. M.; Goodman, L. B.; Kile, J. C.; Holmes, E. C.; Parrish, C. R.
10.1101/2023.03.22.533763 — evolutionary biology — Posted on 2023-03-23
1262 Chiropterans are a hotspot for horizontal transfer of DNA transposons in Mammalia
Paulat, N. S.; Storer, J. M.; Moreno-Santillan, D. D.; Osmanski, A. B.; Sullivan, K. A.; Grimshaw, J. R.; Korstian, J.; Halsey, M.; Garcia, C. J.; Crookshanks, C.; Roberts, J.; Smit, A. F.; Hubley, R.; Rosen, J.; Teeling, E. C.; Vernes, S. C.; Myers, E.; Pippel, M.; Brown, T.; Hiller, M.; Zoonomia Consortium, ; Rojas, D.; Davalos, L. M.; Lindblad-Toh, K.; Karlsson, E. K.; Ray, D. A.
10.1101/2023.03.23.533946 — molecular biology — Posted on 2023-03-23
1263 Group A Streptococcus strains causing meningitis without distinct invasive phenotype
Marquardt, L.; Andreoni, F.; Boumasmoud, M.; Schweizer, T. A.; Heuberger, D.; Parietti, E.; Epprecht, J.; Mattle, D.; Raez, A.; Marques-Maggio, E.; Schuepbach, R.; Hasse, B. K.; Mairpady Shambat, S.; Brugger, S. D.; Zinkernagel, A.
10.1101/2023.03.22.533757 — microbiology — Posted on 2023-03-23
1264 Inoviridae prophage dynamics during diversification, succession and Atlantic invasion of Pacific-native Vibrio parahaemolyticus.
Means, J.; Marcinkiewicz, A.; Foxall, R. L.; Schillaci, C.; DeRosia-Banick, K.; Xu, F.; Hall, J. A.; Jones, s.; Cooper, V. S.; Whistler, C. A.
10.1101/2023.03.23.534014 — microbiology — Posted on 2023-03-23
1266 Intracellular Accumulation-Driven Potentiation of Moxifloxacin Against non-replicating drug-tolerant Mycobacterium tuberculosis through a Prodrug
Kumar, T. A.; Mukherjee, P.; M, S. C.; Birua, S.; Kaul, G.; Akhir, A.; Chopra, S.; Hirschi, J.; Singh, A.; Chakrapani, H.
10.1101/2023.03.23.533925 — microbiology — Posted on 2023-03-23
1269 Antiviral activities of two nucleos(t)ide analogs against vaccinia and mpox viruses in primary human fibroblasts
Dsouza, L.; Pant, A.; Offei, S.; Priyamvada, L.; Pope, B.; Satheshkumar, P. S.; Wang, Z.; Yang, Z.
10.1101/2023.03.23.533943 — microbiology — Posted on 2023-03-23
1270 Adverse outcomes in SARS-CoV-2 infected pregnant mice are gestational age-dependent and resolve with antiviral treatment
Creisher, P. S.; Perry, J. L.; Zhong, W.; Lei, J.; Mulka, K. R.; Ryan, H.; Zhou, R.; Akin, E. H.; Liu, A.; Mitzner, W.; Burd, I.; Pekosz, A.; Klein, S. L.
10.1101/2023.03.23.533961 — microbiology — Posted on 2023-03-23
1271 Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons
Prytkova, I. A.; Liu, Y.; Fernando, M. B.; Gameiro-Ros, I.; Popova, D.; Kamarajan, C.; Xuei, X.; Chorlian, D. B.; Edenberg, H. J.; Tischfield, J. A.; Porjesz, B.; Pang, Z. P.; Hart, R. P.; Goate, A. M.; Slesinger, P. A.
10.1101/2023.03.22.533236 — neuroscience — Posted on 2023-03-23
1273 Inference of single cell profiles from histology stains with the Single-Cell omics from Histology Analysis Framework (SCHAF)
Comiter, C.; Vaishnav, E. D.; Ciapmricotti, M.; Li, B.; Yang, Y.; Rodig, S. J.; Turner, M.; Pfaff, K. L.; Jane-Valbuena, J.; Slyper, M.; Waldman, J.; Vigneau, S.; Wu, J.; Blosser, T. R.; Segerstolpe, A.; Abravanel, D.; Wagle, N.; Zhuang, X.; Rudin, C. M.; Klughammer, J.; Rozenblatt-Rosen, O.; Kobayash-Kirschvink, K. J.; Shu, J.; Regev, A.
10.1101/2023.03.21.533680 — bioinformatics — Posted on 2023-03-23
1274 Transmembrane Stem Factor Nanodiscs Enhanced Revascularization in a Hind Limb Ischemia Model in Diabetic, Hyperlipidemic Rabbits
Takematsu, E.; Massidda, M.; Howe, G.; Goldman, J.; Felli, P.; Mei, L.; Callahan, G.; Sligar, A.; Smalling, R.; Baker, A.
10.1101/2023.03.20.533550 — bioengineering — Posted on 2023-03-23
1277 A glutamatergic DRN-VTA pathway for neuropathic pain and comorbid depression-like behavior modulation
wang, x.; jia, w.; xu, x.; chen, r.; wang, l.; su, x.; xu, p.; liu, x.; wen, j.; liu, y.; liu, x.; zhang, z.; Zhang, Y.
10.1101/2023.03.22.532931 — neuroscience — Posted on 2023-03-23
1279 Dual role of striatal astrocytes in behavioral flexibility and metabolism in the context of obesity
Montalban, E.; Herrera Moro Chao, D.; Ansoult, A.; Pham, C.; Contini, A.; Castel, J.; Hassouna, R.; Hardonk, M.; Petitbon, A.; Foppen, E.; Gangarossa, G.; Trifilieff, P.; Li, D.; Luquet, S.; Martin, C.
10.1101/2023.03.21.533596 — physiology — Posted on 2023-03-23
1280 Opposing Strain Directions on Adjacent Left Ventricular Segments Predict Fibrotic Remodeling after Acute Myocardial Infarction
Dubois-Mignon, T.; Syvannarath, V.; Para, M.; Richard, S.; Sicard, P.; Nicoletti, A.; Caligiuri, G.; Franck, G.
10.1101/2023.03.20.533539 — physiology — Posted on 2023-03-23
1286 Ultra-Rapid and Specific Gelation of Collagen Molecules for Transparent and Tough Gels by Transition Metal Complexation
Suezawa, T.; Sasaki, N.; Assan, N.; Uetake, Y.; Onuma, K.; Sakurai, H.; Katayama, R.; Inoue, M.; Matsusaki, M.
10.1101/2023.03.21.533590 — bioengineering — Posted on 2023-03-23
1287 Cellular heterogeneity of the developing worker honey bee (Apis mellifera) pupa: a single cell transcriptomics analysis
Patir, A.; Raper, A.; Fleming, R.; Henderson, B. E. P.; Murphy, L.; Henderson, N. C.; Clark, E. L.; Freeman, T. C.; Barnett, M. W.
10.1101/2023.03.20.533557 — genomics — Posted on 2023-03-23
1295 Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
Holman, C. D.; Sakers, A. P.; Calhoun, R. P.; Cheng, L.; Fein, E. C.; Jacobs, C.; Tsai, L.; Rosen, E. D.; Seale, P.
10.1101/2023.03.20.533514 — developmental biology — Posted on 2023-03-23
1299 Sex differences in the role of parabrachial in nociception and pain in awake mice
Smith, J.; Ji, Y.; Lorsung, R.; Breault, M.; Koening, J.; Cramer, N. P.; Masri, R.; Keller, A.
10.1101/2023.03.22.533230 — neuroscience — Posted on 2023-03-23
1301 Functional identification of language-responsive channels in individual participants in MEG investigations
Bruffaerts, R.; Pongos, A.; Shain, C.; Lipkin, B.; Siegelman, M.; Wens, V.; Sjogard, M.; Pantazis, D.; Blank, I.; Goldman, S.; De Tiege, X.; Fedorenko, E.
10.1101/2023.03.23.533424 — neuroscience — Posted on 2023-03-23
1303 Pannexin 3 deletion in mice results in knee osteoarthritis and intervertebral disc degeneration after forced treadmill running.
Wakefield, B.; Hutchinson, J. L.; Tang, J.; Brooks, C.; Kanji, R.; Seguin, C. A.; Penuela, S.; Beier, F.
10.1101/2023.03.20.532801 — physiology — Posted on 2023-03-23
1307 Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis
Sahu, B.; Razzoli, M.; McGonigle, S.; Pallais, J. P.; Nguyen, M.; Sadahiro, M.; Jiang, C.; Lin, W.-J.; Kelley, K.; Rodriguez, P.; Mansk, R.; Cero, C.; Caviola, G.; Palanza, P.; Rao, L.; Beetch, M.; Alejandro, E.; Sham, Y.; Frontini, A.; Salton, S.; Bartolomucci, A.
10.1101/2023.03.23.532619 — physiology — Posted on 2023-03-23
1309 Overexpressed Malat1 Drives Metastasis through Inflammatory Reprogramming of Lung Adenocarcinoma Microenvironment
Martinez-Terroba, E.; de Miguel, F. J.; Li, V.; Robles-Oteiza, C.; Politi, K.; Zamudio, J. R.; Dimitrova, N.
10.1101/2023.03.20.533534 — cancer biology — Posted on 2023-03-23
1310 Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade
Mahmood, M.; Liu, E. M.; Shergold, A. L.; Tolla, E.; Tait-Mulder, J.; Uribe, A. H.; Shokry, E.; Young, A. L.; Lilla, S.; Kim, M.; Park, T.; Manchon, J. L.; Rodriguez-Antona, C.; Walters, R. C.; Springett, R. J.; Blaza, J. N.; Zanivan, S.; Sumpton, D. A.; Roberts, E. W.; Reznik, E.; Gammage, P. A.
10.1101/2023.03.21.533091 — cancer biology — Posted on 2023-03-23
1313 RExPRT: a machine learning tool to predict pathogenicity of tandem repeat loci
Fazal, S.; Danzi, M.; Xu, I.; Kobren, S. N.; Sunyaev, S.; Reuter, C.; Marwaha, S.; Wheeler, M. T.; Dolzhenko, E.; Lucas, F.; Wuchty, S.; Tekin, M.; Zuchner, S.; Aguiar-Pulido, V.
10.1101/2023.03.22.533484 — bioinformatics — Posted on 2023-03-23
1318 THE RHODOEXPLORER PLATFORM FOR RED ALGAL GENOMICS AND WHOLE GENOME ASSEMBLIES FOR SEVERAL GRACILARIA SPECIES
Lipinska, A. P.; Krueger-Hadfield, S. A.; Godfroy, O.; Dittami, S.; Ayres-Ostrock, L.; Bonthond, G.; Brillet-Gueguen, L.; Coelho, S.; Corre, E.; Cossard, G.; Destombe, C.; Epperlein, P.; Faugeron, S.; Ficko-Blean, E.; Beltran, J.; Lavaut, E.; Le Bars, A.; Marchi, F.; Mauger, S.; Michel, G.; Potin, P.; Scornet, D.; Sotka, E. E.; Weinberger, F.; Cabral de Oliveira, M.; Guillemin, M.-L.; Plastino, E.; Valero, M.
10.1101/2023.03.20.533491 — genomics — Posted on 2023-03-23
1324 CD32 allows capturing blood cells emergence in slow motion during human embryonic development
Scarfo, R.; Abou Alezz, M.; El Khoury, M.; Gersch, A.; Li, Z.-Y.; Luff, S. A.; Valsoni, S.; Cascione, S.; Emma, D.; Merelli, I.; Freund, J.-N.; Sturgeon, C. M.; Tavian, M.; Ditadi, A.
10.1101/2023.03.23.530597 — developmental biology — Posted on 2023-03-23
1325 Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster
Hurtado, A.; Mota-Gomez, I.; Lao, M.; Real, F. M.; Jedamzick, J.; Burgos, M.; Lupianez, D. G.; Jimenez, R.; Barrionuevo, F. J.
10.1101/2023.03.22.533123 — developmental biology — Posted on 2023-03-23
1326 Amino acid auxotrophies in human gut bacteria are linked to higher microbiome diversity and long-term stability
Busche, S.; Harris, D. M.; Zimmermann, J.; Schuchardt, S.; Oumari, M.; Frank, D.; Bang, C.; Rosenstiel, P.; Schreiber, S.; Frey, N.; Franke, A.; Aden, K.; Waschina, S.
10.1101/2023.03.23.532984 — microbiology — Posted on 2023-03-23
1329 Caloric restriction prevents inflammation and insulin dysfunction in middle-aged ovariectomized mice
Sapatini, L. R.; Calsa, B.; Marin, L. J.; Helaehil, J. V.; Chiarotto, G.; Amaral, M. E.
10.1101/2023.02.09.527836 — physiology — Posted on 2023-03-23
1330 Physics-based inverse design of cholesterolattracting transmembrane helices reveals aparadoxical role of hydrophobic length
Methorst, J.; Verwei, N.; Hoffmann, C.; Chodnicki, P.; Sansevrino, R.; Wang, H.; van Hilten, N.; Aschmann, D.; Kros, A.; Andreas, L.; Czub, J.; Milovanovic, D.; Risselada, H. J.
10.1101/2021.07.01.450699 — biophysics — Posted on 2023-03-23
1331 Finding Haplotypic Signatures in Proteins
Vasicek, J.; Skiadopoulou, D.; Kuznetsova, K. G.; Wen, B.; Johansson, S.; Njolstad, P. R.; Bruckner, S.; Kall, L.; Vaudel, M.
10.1101/2022.11.21.517096 — bioinformatics — Posted on 2023-03-23
1332 Genomic insights into greater yam tuber quality traits
Zotta Mota, A.; DOSSA, K.; Lechaudel, M.; CORNET, D.; MOURNET, P.; LOPEZ, D.; CHAIR, H.
10.1101/2023.03.17.532727 — genomics — Posted on 2023-03-23
1333 A Dynamic population of prophase CENP-C is required for meiotic chromosome segregation
Fellmeth, J.; Sturm, H.; Jang, J. K.; Changela, N.; Parikh, A.; Persaud, M.; McKim, K. S.
10.1101/2023.03.13.532437 — genetics — Posted on 2023-03-23
1334 Taxonomic distribution of metabolic functions underpins nutrient cycling in Trichodesmium consortia
Koedooder, C.; Zhang, F.; Wang, S.; Haley, S. T.; Tolic, N.; Nicora, C. D.; Glavina del Rio, T.; Basu, S.; Gledhill, M.; Boiteau, R.; Dyhrman, S.; Rubin-Blum, M.; Shaked, Y.
10.1101/2023.03.15.532517 — microbiology — Posted on 2023-03-23
1336 Genomic glucocorticoid receptor effects guide acute stress-induced delayed anxiety and basolateral amygdala spine plasticity in rats.
Novaes, L. S.; Bueno-de-Camargo, L. M.; Shigeo-de-Almeida, A.; Juliano, V. A. L.; Goosens, K.; Munhoz, C. D.
10.1101/2022.09.19.508565 — neuroscience — Posted on 2023-03-23
1337 Oscillatory brain activity as unified control mechanism for working memory and mentalizing
Friedrich, E. V. C.; Hilla, Y.; Sterner, E. F.; Ostermeier, S. S.; Behnke, L.; Sauseng, P.
10.1101/2023.02.13.528423 — neuroscience — Posted on 2023-03-23
1338 Compromised beta-cell identity in type 2 diabetes
Dutta, P.; Merabet, N.; Quax, R.; Carlotti, F.; Sloot, P. M. A.
10.1101/2023.03.20.533468 — systems biology — Posted on 2023-03-23
1341 Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens
Yao, M.; Preall, J.; Yeh, J.; Pappin, D.; Cifani, P.; Zhao, Y. Z.; Shen, S.; Moresco, P.; He, B.; Patel, H.; Habowski, A.; King, D.; Raphael, K.; Rishi, A.; Sejpal, D.; Weiss, M.; Tuveson, D.; Fearon, D.
10.1101/2023.03.20.533453 — cancer biology — Posted on 2023-03-23
1342 Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer
San Martin, R.; Das, P.; Xue, T.; Brown, M. R.; Dos Reis Marques, R.; Essington, M.; Gonzalez, A.; McCord, R. P.
10.1101/2023.03.20.533462 — cancer biology — Posted on 2023-03-23
1344 Impact of Phosphorylation on alpha-Synuclein Structural Determinants
Dorn, A. E.; de Bruyn, E.; Rossetti, G.; Fernandez, C.; Outeiro, T. F.; Schulz, J. B.; Carloni, P.
10.1101/2023.03.10.531864 — biophysics — Posted on 2023-03-23
1346 A meta-analysis of immune cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes
Luo, Q.; Dwaraka, V. B.; Chen, Q.; Tong, H.; Zhu, T.; Seale, K.; Raffaele, J. M.; Zheng, S. C.; Mendez, T. L.; Chen, Y.; Begum, S.; Mendez, K.; Voisin, S.; Eynon, N.; Lasky-Su, J. A.; Smith, R.; Teschendorff, A. E.
10.1101/2023.03.20.533349 — bioinformatics — Posted on 2023-03-23
1347 Sustained In Vivo Perfusion of a Re-Endothelialized Tissue Engineered Kidney Graft in a Human-Scale Animal Model
Uzarski, J. S.; Beck, E. C.; Russell, E. E.; Vanderslice, E. J.; Holzner, M. L.; Wadhera, V.; Adamson, D.; Shapiro, R.; Davidow, D. S.; Ross, J. J.; Florman, S. S.
10.1101/2023.03.20.532642 — bioengineering — Posted on 2023-03-23
1348 Printing double network tough hydrogels using Temperature-Controlled Projection Stereolithography (TOPS)
Soman, P.; Kunwar, P.; Poudel, A.; Xiong, Z.; Aryal, U.; Geffert, Z. J.; Poudel, S.; Fougnier, D.; Gitsov, I.
10.1101/2023.03.20.533294 — bioengineering — Posted on 2023-03-23
1349 Phased chromosome-scale genome assembly of an asexual, allopolyploid root-knot nematode reveals complex subgenomic structure
Winter, M. R.; Taranto, A. P.; Yimer, H. Z.; Coomer-Blundell, A.; Siddique, S.; Williamson, V. M.; Lunt, D. H.
10.1101/2023.03.20.533402 — genomics — Posted on 2023-03-23
1350 Inferring compound heterozygosity from large-scale exome sequencing data
Guo, M. H.; Francioli, L. C.; Stenton, S. L.; Goodrich, J. K.; Watts, N. A.; Singer-Berk, M.; Groopman, E.; Darnowsky, P. W.; Solomonson, M.; Baxter, S.; gnomAD Project Consortium, ; Tiao, G.; Neale, B. M.; Hirschhorn, J. N.; Rehm, H. L.; Daly, M. J.; O'Donnell-Luria, A.; Karczewski, K. J.; MacArthur, D. G.; Samocha, K. E.
10.1101/2023.03.19.533370 — genomics — Posted on 2023-03-23
1351 A new Plasmodium vivax reference genome for South American isolates
De Meulenaere, K.; Cuypers, B.; Gamboa, D.; Laukens, K.; Rosanas-Urgell, A.
10.1101/2023.03.14.532329 — genetics — Posted on 2023-03-23
1354 Establishment and validation of a High-throughput Micro-Neutralization assay for Respiratory Syncytial Virus (subtypes A and B)
Bonifazi, C.; Trombetta, C. M.; Barneschi, I.; Latanza, S.; Leopoldi, S.; Benincasa, L.; Leonardi, M.; Semplici, C.; Piu, P.; Marchi, S.; Montomoli, E.; Manenti, A.
10.1101/2023.03.20.533425 — immunology — Posted on 2023-03-23
1355 In vivo Locus Coeruleus activity while awake is associated with REM sleep quality in healthy older individuals
Koshmanova, E.; Berger, A.; Beckers, E.; Campbell, I.; Mortazavi, N.; Sharifpour, R.; Paparella, I.; Balda, F.; Berthomier, C.; Degueldre, C.; Salmon, E.; Lamalle, L.; Bastin, C.; Van Egroo, M.; Phillips, C.; Maquet, P.; Collette, F.; Muto, V.; Chylinski, D.; Jacobs, H.; Talwar, P.; Sherif, S.; Vandewalle, G.
10.1101/2023.02.10.527974 — neuroscience — Posted on 2023-03-23
1358 PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer
Gordon, N.; Gallagher, P. T.; Neupane, N. P.; Mandigo, A. C.; McCann, J. K.; Dylgjeri, E.; Vasilevskaya, I.; McNair, C.; Paller, C. J.; Kelly, W. K.; Knudsen, K. E.; Shafi, A. A.; Schiewer, M. J.
10.1101/2023.03.23.533944 — cancer biology — Posted on 2023-03-23
1364 High throughput detection of variation in single-cell whole transcriptome through streamlined scFAST-seq
Jiao, S.; Zhao, Y.; Gong, Y.; Sang, G.; Chen, J.; Zhao, M.; Shi, H.; Han, J.; Sun, J.; Guan, Y.; Ma, X.; Zhang, G.
10.1101/2023.03.19.533382 — genomics — Posted on 2023-03-23
1371 Standardization of suspension and imaging mass cytometry readouts for clinical decision making
Casanova, R.; Xu, S.; Sivapatham, S.; Jacobs, A.; Engler, S.; Tumor Profiler Consortium, ; Levesque, M. P.; Dummer, R.; Bodenmiller, B.; Chevrier, S.
10.1101/2023.03.19.531228 — cancer biology — Posted on 2023-03-23
1374 Turbulence and blood washout in presence of mitral regurgitation: a computational fluid-dynamics study in the complete left heart
Bennati, L.; Giambruno, V.; Renzi, F.; Di Nicola, V.; Maffeis, C.; Puppini, G.; Luciani, G. B.; Vergara, C.
10.1101/2023.03.19.533094 — bioengineering — Posted on 2023-03-23
1375 Bayesian Inference for Brain Source Imaging with Joint Estimation of Structured Low-rank Noise
Ghosh, S.; Cai, C.; Gao, Y.; Hashemi, A.; Haufe, S.; Sekihara, K.; Raj, A.; Nagarajan, S.
10.1101/2023.03.19.533348 — bioengineering — Posted on 2023-03-23
1378 Telomemore enables single-cell analysis of cell cycle and chromatin condensation
Mihai, I. S.; Rosenbaum, W.; Dernstedt, A.; Groning, R.; Trygg, J.; Forsell, M.; Henriksson, J.
10.1101/2023.03.19.533267 — immunology — Posted on 2023-03-23
1379 A tale of two pumps: Blue light and ABA alter Arabidopsis leaf hydraulics via bundle sheath cells H+-pumps and channels
Torne-Srivastava, T.; Grunwald, Y.; Rosenwald, M.; Dalal, A.; Yaaran, A.; Schebtaev, V.; Moshelion, M.; Moran, N.
10.1101/2023.03.21.533687 — plant biology — Posted on 2023-03-23
1380 mRNA challenge predicts brain cancer immunogenicity and response to checkpoint inhibitors
Castillo, P.; Ogando-Rivas, E.; Geffrard, H.; Pepe, A.; Liu, R.; Nguyen, D. T.; Pedro, D.; Zhang, D.; DeVries, A.; Qdaisat, S.; Karachi, A.; Rahman, M.; Weidert, F.; Milner, R.; Huang, J.; Ligon, J. A.; Silver, N.; Li, D.; Lee, J.-H.; Carrera-Justiz, S.; Mitchell, D. A.; Mendez-Gomez, H.; Sawyer, W. G.; Sayour, E. J.
10.1101/2023.03.18.532056 — cancer biology — Posted on 2023-03-23
1383 Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism
Levy, D.; Abadchi, S. N.; Shababi, N.; Ravari, M. R.; Pirolli, N. H.; Bergeron, C.; Obiorah, A.; Mokhtari-Esbuie, F.; Gheshlaghi, S.; Abraham, J. M.; Smith, I. M.; Powsner, E.; Solomon, T.; Harmon, J. W.; Jay, S. M.
10.1101/2023.03.19.533334 — bioengineering — Posted on 2023-03-23
1384 A novel Fis1 inhibiting peptide reverses diabetic endothelial dysfunction in human resistance arteries
Nolden, K. A.; Egner, J. M.; Egner, J. M.; Wang, J.; Harwig, M. C.; Puppala, V. K.; Hofeld, B. C.; Arnold, L. A.; Trykall, D. Z.; Peterson, F. C.; Roberts, M. L.; Jensen, D. M.; Hill, R. B.; Widlansky, M. E.
10.1101/2020.11.16.385054 — physiology — Posted on 2023-03-23
1385 Interneuron diversity in the human dorsal striatum
Garma, L.; Harder, L.; Barba-Reyes, J. M.; Diez-Salguero, M.; Serrano-Pozo, A.; Hyman, B. T.; Munoz-Manchado, A. B.
10.1101/2023.03.22.533839 — neuroscience — Posted on 2023-03-23
1388 Personal interests amplify engagement of language regions in the brains of children with and without autism
D'Mello, A. M.; Olson, H. A.; Johnson, K. T.; Nishith, S.; Frosch, I. R.; Gabrieli, J. D. E.
10.1101/2023.03.21.533695 — neuroscience — Posted on 2023-03-23
1392 Artificial selection footprints in domestic chicken genomes
Wu, S.; Dou, T.; Wang, K.; Yuan, S.; Yan, S.; Xu, Z.; Liu, Y.; Jian, Z.; Zhao, J.; Zhao, R.; Wu, H.; Gu, D.; Liu, L.; Wu, D.-D.; Li, Q.; Su, Z.; Ge, C.; Jia, J.
10.1101/2023.03.22.533830 — bioinformatics — Posted on 2023-03-23
1396 Reticular adhesion formation is mediated by flat clathrin lattices and opposed by fibrillar adhesions
Hakanpaa, L.; Abouelezz, A.; Lenaerts, A.-S.; Culfa, S.; Algie, M.; Barlund, J.; Katajisto, P.; McMahon, H. T.; Almeida-Souza, L.
10.1101/2022.05.30.494022 — cell biology — Posted on 2023-03-23
1400 Widespread readthrough events in plants reveal unprecedented plasticity of stop codons
Wu, L.; Wu, S.-B.; Tian, Z.; Zhang, Y.; Li, H.; Shen, Y.; Wang, S.; Tian, L.; Yin, H.; Shi, J.; Xing, A.; Zhang, J.; Ali, U.; Sami, A.; Chen, X.; Gao, C.; Zhao, Y.; Lyu, Y.; Wang, X.; Chen, Y.
10.1101/2023.03.20.533458 — plant biology — Posted on 2023-03-23
1402 Rapid systemic responses of Arabidopsis to waterlogging stress
Pelaez-Vico, M. A.; Tukuli, A.; Singh, P.; Mendoza-Cozatl, D. G.; Joshi, T. G.; Mittler, R.
10.1101/2023.03.22.533859 — plant biology — Posted on 2023-03-23
1405 Protective role of protease-activated receptor-2 in anaphylaxis model mice
Nakazawa, M.; Tochinai, R.; Fujii, W.; Yonezawa, T.; Momoi, Y.; Maeda, S.
10.1101/2023.03.22.533779 — molecular biology — Posted on 2023-03-22
1406 TCR-pMHC complex formation triggers CD3 dynamics
van Eerden, F. J.; Sherif, A. A.; Covarrubias, M. A. L.; Millius, A.; Lu, X.; Ishizuka, S.; Yamasaki, S.; Standley, D. M.
10.1101/2022.07.27.501668 — molecular biology — Posted on 2023-03-22
1409 Identification of a Novel PARP14 Site Motif and Glycohydrolase Specificity Using TLC-MALDI-TOF
Javed, Z.; Nguyen, H. H.; Harker, K.; Mohr, C. M.; Vano, P.; Wallace, S. R.; Silvers, C.; Sim, C.; Turumella, S.; Flinn, A.; Carter-O'Connell, I.
10.1101/2023.03.22.533863 — biochemistry — Posted on 2023-03-22
1412 Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model
Plumlee, C. R.; Barrett, H. W.; Shao, D. E.; Lien, K. A.; Cross, L. M.; Cohen, S. B.; Edlefsen, P. T.; Urdahl, K. B.
10.1101/2023.03.22.533820 — microbiology — Posted on 2023-03-22
1414 Tuft cell-derived acetylcholine regulates epithelial fluid secretion
Billipp, T. E.; Fung, C.; Webeck, L. M.; Sargent, D. B.; Gologorsky, M. B.; McDaniel, M. M.; Kasal, D. N.; McGinty, J. W.; Barrow, K. A.; Rich, L. M.; Barilli, A.; Sabat, M.; Debley, J. S.; Myers, R.; Howitt, M. R.; von Moltke, J.
10.1101/2023.03.17.533208 — immunology — Posted on 2023-03-22
1416 Mammalian cell characterisation by non-invasive plate reader assay
Grob, A.; Bena, C. E.; Di Blasi, R.; Pessina, D.; Sood, M.; Yunyue, Z.; Bosia, C.; Isalan, M.; Ceroni, F.
10.1101/2023.03.22.533848 — synthetic biology — Posted on 2023-03-22
1417 Thermogenetic control of Ca2+ levels in cells and tissues
Ermakova, Y. G.; Waadt, R.; Ozturk, M. S.; Roshchin, M.; Lanin, A. A.; Chebotarev, A.; Pochechuev, M.; Pak, V.; Kelmanson, I.; Smolyarovasmol, D.; Keutler, K.; Matyushenko, A. M.; Tischer, C. V.; Balaban, P. M.; Nikitin, E. S.; Schumacher, K.; Zheltikov, A.; Prevedel, R.; Schultz, C.; Belousov, V. V.
10.1101/2023.03.22.533774 — synthetic biology — Posted on 2023-03-22
1418 GPR41/43 regulates blood pressure by improving gut epithelial barrier integrity to prevent TLR4 activation and renal inflammation
R Muralitharan, R.; Zheng, T.; Dinakis, E.; Xie, L.; Barboro-Wahl, A.; Jama, H.; Nakai, M.; Paterson, M.; Johnson, C.; Salimova, E.; Bittto, N.; Liaskos, M.-K.; Kaye, D. M.; O'Donnell, J.; Mackay, C. R.; Marques, F. Z.
10.1101/2023.03.20.533376 — physiology — Posted on 2023-03-22
1420 CAGEE: computational analysis of gene expression evolution
Bertram, J.; Fulton, B.; Tourigny, J. P.; Pena-Garcia, Y.; Moyle, L. C.; Hahn, M. W.
10.1101/2022.11.18.517074 — bioinformatics — Posted on 2023-03-22
1421 High performance Legionella pneumophila source attribution using genomics-based machine learning classification
Buultjens, A. H.; Vandelannoote, K.; Mercoulia, K. H.; Ballard, S. A.; Sloggett, C.; Howden, B.; Seeman, T.; Stinear, T. P.
10.1101/2023.03.19.532693 — bioinformatics — Posted on 2023-03-22
1423 Shotgun proteomic analysis of the caterpillar Lonomia obliqua (Lepitoptera, Saturniidae) hemolymph and effects in rat hippocampal neurons culture
Maggi, S.; Pinto, A. F.; Udo, M. S. B.; Alencar da Silva, M. A.; Garcia, R. C. T.; Minetto, L.; Tasso, L.; Machado, P.; Santos, D. S.; Silva Junior, P. I.; Barcellos, T.; Mendonca, R. Z.; Marcourakis, T.; Moura, S.
10.1101/2023.03.20.533482 — biochemistry — Posted on 2023-03-22
1424 Structure and Function of the Dot/Icm T4SS
Dutka, P.; Liu, Y.; Maggi, S.; Ghosal, D.; Wang, J.; Carter, S. D.; Zhao, W.; Vijayrajratnam, S.; Vogel, J. P.; Jensen, G. J.
10.1101/2023.03.22.533729 — biochemistry — Posted on 2023-03-22
1427 An epigenetic molluscicide
Luviano, N.; Halby, L.; Jallet, C.; Arimondo, P.; Cosseau, C.; Grunau, C.
10.1101/2023.03.21.533666 — molecular biology — Posted on 2023-03-22
1428 The C. elegans proteome response to two protective Pseudomonas symbionts
Pees, B.; Peters, L.; Treitz, C.; Hamerich, I. K.; Kissoyan, K. A.; Tholey, A.; Dierking, K.
10.1101/2023.03.22.533766 — molecular biology — Posted on 2023-03-22
1429 Protective role of protease-activated receptor-2 in anaphylaxis model mice
Nakazawa, M.; Tochinai, R.; Fujii, W.; Yonezawa, T.; Momoi, Y.; Maeda, S.
10.1101/2023.03.22.533779 — molecular biology — Posted on 2023-03-22
1430 Temporal progression of anaerobic fungal communities in dairy calves from birth to maturity
Jones, A. L.; Clayburn, J.; Pribil, E.; Foote, A.; Montgomery, D.; Elshahed, M.; Youssef, N. H.
10.1101/2023.03.22.533786 — microbiology — Posted on 2023-03-22
1431 The structural basis of hyperpromiscuity in a core combinatorial network of Type II toxin-antitoxin and related phage defence systems
Ernits, K.; Saha, C. K.; Brodiazhenko, T.; Chouhan, B.; Shenoy, A.; Duque-Pedraza, J. J.; Bojar, V.; Nakamoto, J. A.; Kurata, T.; Egorov, A.; Shyrokova, L.; Johansson, M. J. O.; Mets, T.; Rustamova, A.; Dzigurski, J.; Tenson, T.; Garcia-Pino, A.; Elofsson, A.; Hauryliuk, V.; Atkinson, G. C.
10.1101/2023.03.22.533649 — microbiology — Posted on 2023-03-22
1432 Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study
Ecklu-Mensah, G.; Choo-Kang, C.; Maseng, M. G.; Donato, S.; Bovet, P.; Bedu-Addo, K.; Plange-Rhule, J.; Forrester, T. E.; Lambert, E. V.; Rae, D.; Luke, A.; Layden, B. T.; O'Keefe, S.; Gilbert, J. A.; Dugas, L. R.
10.1101/2023.03.21.533195 — microbiology — Posted on 2023-03-22
1434 Fever like temperature impacts on Staphylococcus aureus and Pseudomonas aeruginosa interaction, physiology, and virulence both in vitro and in vivo
Solar Venero, E. C.; Galeano, M. B.; Luqman, A.; Ricardi, M.; Serral, F.; Fernandez Do Porto, D.; Robaldi, S. A.; Ashari, B. A. Z.; Munif, T. H.; Egoburo, D. E.; Nemirovsky, S.; Escalante, J.; Nishimura, B.; Ramirez, M. S.; Götz, F.; Tribelli, P. M.
10.1101/2023.03.21.529514 — microbiology — Posted on 2023-03-22
1435 EGGNet, a generalizable geometric deep learning framework for protein complex pose scoring
Wang, Z.; Brand, R.; Adolf-Bryfogle, J.; Grewal, J.; Qi, Y.; Combs, S. A.; Golovach, N.; Alford, R.; Rangwala, H.; Clark, P. M.
10.1101/2023.03.22.533800 — synthetic biology — Posted on 2023-03-22
1436 Multicellular PD Control in Microbial Consortia
Martinelli, V.; Salzano, D.; Fiore, D.; di Bernardo, M.
10.1101/2023.03.22.533755 — synthetic biology — Posted on 2023-03-22
1438 Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents
Stockwell, S. R.; Scott, D. E.; Fischer, G.; Guarino, E.; Rooney, T. P. C.; Fang, T.-S.; Moschetti, T.; Srinivasan, R.; Alza, E.; Asteian, A.; Dagostin, C.; Alcaide, A.; Rocaboy, M.; Blaszczyk, B.; Higueruelo, A.; Wang, X.; Rossmann, M.; Perrior, T. R.; Blundell, T. L.; Spring, D. R.; McKenzie, G.; Abell, C.; Skidmore, J.; Hyvönen, M.; Venkitaraman, A. R.
10.1101/2023.03.22.533679 — biochemistry — Posted on 2023-03-22
1442 Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2
Wang, Q.; Li, Z.; Guo, Y.; Mellis, I. A.; Iketani, S.; Liu, M.; Yu, J.; Valdez, R.; Lauring, A. S.; Sheng, Z.; Gordon, A.; Liu, L.; Ho, D. D.
10.1101/2023.03.22.533805 — microbiology — Posted on 2023-03-22
1444 Emerging Antifungal Resistance in Falco Species: A Novel Model for Human Medicine
DAS, S.; CHRISTU, S. D.; SILVANOSE, C.; BINOY, A.; AZMANIS, P.; DI SOMMA, A.; GLADSTON, J. V.
10.1101/2023.03.22.533837 — microbiology — Posted on 2023-03-22
1445 B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition model
Hogan, C. H.; Owens, S. M.; Reynoso, G. V.; Kirillov, V.; Meyer, T. J.; Zelazowska, M. A.; Liu, B.; Li, X.; Chikhalya, A.; Dong, Q.; Khairallah, C.; Reich, N. C.; Sheridan, B.; McBride, K. M.; Hearing, P.; Hickman, H. D.; Forrest, J. C.; Krug, L. T.
10.1101/2023.03.22.533727 — microbiology — Posted on 2023-03-22
1446 Interspecies interactions determine growth dynamics of biopolymer degrading populations in microbial communities.
D'souza, G.; Schwartzman, J.; Keegstra, J.; Schreier, J. E.; Daniels, M.; Cordero, O.; Stocker, R.; Ackermann, M.
10.1101/2023.03.22.533748 — microbiology — Posted on 2023-03-22
1448 Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells
Tsuchida, C. A.; Brandes, N.; Bueno, R.; Trinidad, M.; Mazumder, T.; Yu, B.; Hwang, B.; Chang, C.; Liu, J.; Sun, Y.; Hopkins, C. R.; Parker, K. R.; Qi, Y.; Satpathy, A.; Stadtmauer, E.; Cate, J. H. D.; Eyquem, J.; Fraietta, J. A.; June, C. H.; Chang, H. Y.; Ye, C. J.; Doudna, J. A.
10.1101/2023.03.22.533709 — cell biology — Posted on 2023-03-22
1449 An endocytic myosin essential for plasma membrane invagination powers motility against resistance
Pedersen, R. T.; Snoberger, A.; Pyrpassopoulos, S.; Safer, D.; Drubin, D. G.; Ostap, E. M.
10.1101/2023.03.21.533689 — cell biology — Posted on 2023-03-22
1452 Genetic screening identifies integrated stress response kinase HRI (EIF2AK1) as a negative regulator of PINK1 and mitophagy signalling
Singh, P.; Volpi, I.; Agarwal, S.; Wilhelm, L. P.; Becchi, G.; Macartney, T.; Toth, R.; Rousseau, A.; Masson, G.; Ganley, I. G.; Muqit, M. M. K.
10.1101/2023.03.20.533516 — biochemistry — Posted on 2023-03-22
1455 Wolbachia is a nutritional symbiont in Drosophila melanogaster
Lindsey, A. R.; Parish, A. J.; Newton, I. L.; Tennessen, J.; Jones, M. W.; Stark, N.
10.1101/2023.01.20.524972 — developmental biology — Posted on 2023-03-22
1456 Neural circuitry for maternal oxytocin release induced by infant cries
Valtcheva, S.; Issa, H. A.; Bair-Marshall, C. J.; Martin, K. A.; Jung, K.; Zhang, Y.; Kwon, H.-B.; Froemke, R. C.
10.1101/2021.03.25.436883 — neuroscience — Posted on 2023-03-22
1457 Large-scale unsupervised discovery of excitatory morphological cell types in mouse visual cortex
Weis, M. A.; Papadopoulos, S.; Hansel, L.; Lueddecke, T.; Celii, B.; Fahey, P. G.; Bae, J. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Collman, F.; da Costa, N. M.; Dorkenwald, S.; Elabbady, L.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Reid, R. C.; Schneider-Mizell, C. M.; Seung, H. S.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yin, W.; Yu, S.-c.; Reimer, J.; Tolias, A. S.; Ecker, A.
10.1101/2022.12.22.521541 — neuroscience — Posted on 2023-03-22
1459 EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis
Chakraborty, S.; Bhat, A. M.; Mushtaq, I.; Luan, H.; Kalluchi, A.; Mirza, S.; Storck, M. D.; Chaturvedi, N.; Lopez-Guerrero, J. A.; Llombart-Bosch, A.; Machado, I.; Scotlandi, K.; Meza, J. L.; Ghosal, G.; Coulter, D. W.; Rowley, J. M.; Band, V.; Mohapatra, B. C.; Band, H.
10.1101/2023.01.15.524130 — cancer biology — Posted on 2023-03-22
1460 Dynamic matrices with DNA-encoded viscoelasticity for advanced cell and organoid culture
Peng, Y.-H.; Hsiao, S.-K.; Gupta, K.; Ruland, A.; Auernhammer, G. K.; Maitz, M. F.; Boye, S.; Lattner, J.; Gerri, C.; Honigmann, A.; Werner, C.; Krieg, E.
10.1101/2022.10.08.510936 — bioengineering — Posted on 2023-03-22
1462 The control of protein arginine phosphorylation facilitates proteostasis by an AAA+ chaperone protease system
Alver, R.; Hantke, I.; Cornejo, F. A.; Gunka, K.; Rämisch, S.; Moliere, N.; Charpentier, E.; Turgay, K.
10.1101/2022.09.15.508104 — microbiology — Posted on 2023-03-22
1463 Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs
Bagato, O.; Balkema-Buschmann, A.; Todt, D.; Weber, S.; Goemer, A.; Qu, B.; Miskey, C.; Mettenleiter, T. C.; Finke, S.; Brown, R. J. P.; Breithaupt, A.; Ushakov, D. S.
10.1101/2023.03.22.533759 — immunology — Posted on 2023-03-22
1464 BCG administration promotes the long-term protection afforded by a single-dose intranasal adenovirus-based SARS-CoV-2 vaccine
Perera, D. J.; Domenech, P.; Babuadze, G. G.; Naghibosadat, M.; Alvarez, F.; Koger-Pease, C.; Labrie, L.; Stuible, M.; Durocher, Y.; Piccirillo, C. A.; Lametti, A.; Fiset, P. O.; Elahi, S. M.; Kobinger, G. P.; Gilbert, R.; Olivier, M.; Kozak, R.; Reed, M. B.; Ndao, M.
10.1101/2023.03.21.533720 — immunology — Posted on 2023-03-22
1465 Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes
Fodder, K.; Murthy, M.; Rizzu, P.; Toomey, C. E.; Hasan, R.; Humphrey, J.; Raj, T.; Lunnon, K.; Mill, J.; Heutink, P.; Lashley, T.; Bettencourt, C.
10.1101/2022.10.21.513088 — neuroscience — Posted on 2023-03-22
1468 Kinetic stabilization of translation-repression condensates by a neuron-specific microexon
Garcia-Cabau, C.; Bartomeu, A.; Balaceanu, A.; Tesei, G.; Duran-Arque, B.; Fernandez-Alfara, M.; Martin, J.; De Pace, C.; Ruiz-Perez, L.; Garcia, J.; Battaglia, G.; Lindorff-Larsen, K.; Mendez, R.; Salvatella, X.
10.1101/2023.03.19.532587 — biophysics — Posted on 2023-03-22
1472 Quantitative analysis of food web dynamics in a low export ecosystem
McNair, H. M.; Meyer, M. G.; Lerch, S. J.; Maas, A. E.; Stephens, B. M.; Fox, J.; Buck, K. N.; Burns, S. M.; Cetinic, I.; Cohn, M. R.; Durkin, C.; Gifford, S. M.; Gong, W.; Graff, J. R.; Jenkins, B.; Jones, E. L.; Santoro, A. E.; Shea, C. H.; Stamieszkin, K.; Steinberg, D. K.; Marchetti, A.; Carlson, C. A.; Menden-Deuer, S.; Brzezinski, M. A.; Siegel, D. A.; Rynearson, T. A.
10.1101/2023.03.17.532807 — ecology — Posted on 2023-03-22
1473 Pharmacologically targeting KRASG12D in PDAC models:tumor cell intrinsic and extrinsic impact
Kumarasamy, V.; Frangou, C.; Wang, J.; Wan, Y.; Dynka, A.; Rosenheck, H.; Dey, P.; Abel, E. V.; Knudsen, E.; Witkiewicz, A.
10.1101/2023.03.18.533261 — cancer biology — Posted on 2023-03-22
1474 Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever
Gravett, M. S. C.; Klebl, D. P.; Harlen, O. G.; Read, D. J.; Harris, S. A.; Muench, S. P.; Peckham, M.
10.1101/2023.03.19.533260 — biophysics — Posted on 2023-03-22
1477 Structural basis for functional properties of cytochrome c oxidase
Ishigami, I.; Sierra, R. G.; Su, Z.; Peck, A.; Wang, C.; Poitevin, F.; Lisova, S.; Hayes, B.; Moss, F. R.; Boutet, S.; Sublett, R. E.; Yoon, C. H.; Yeh, S.-R.; Rousseau, D. L.
10.1101/2023.03.20.530986 — biophysics — Posted on 2023-03-22
1479 Genetic screening identifies integrated stress response kinase HRI (EIF2AK1) as a negative regulator of PINK1 and mitophagy signalling
Singh, P.; Volpi, I.; Agarwal, S.; Wilhelm, L. P.; Becchi, G.; Macartney, T.; Toth, R.; Rousseau, A.; Masson, G.; Ganley, I. G.; Muqit, M. M. K.
10.1101/2023.03.20.533516 — biochemistry — Posted on 2023-03-22
1480 Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations
Zhao, S.; Mekbib, K. Y.; van der Ent, M. A.; Allington, G.; Prendergast, A.; Chau, J. E.; Smith, H.; Shohfi, J.; Ocken, J.; Duran, D.; Furey, C. G.; Le, H. T.; Duy, P. Q.; Reeves, B. C.; Zhang, J.; Nelson-Williams, C.; Chen, D.; Li, B.; Nottoli, T.; Bai, S.; Rolle, M.; Zeng, X.; Dong, W.; Fu, P.-Y.; Wang, Y.-C.; Mane, S.; Piwowarczyk, P.; Fehnel, K. P.; See, A. P.; Iskandar, B. J.; Aagaard-Kienitz, B.; Kundishora, A. J.; DeSpenza, T.; Greenberg, A. B. W.; Kidanemariam, S. M.; Prendergast, A.; Johnston, J. M.; Jackson, E.; Storm, P. B.; Lang, S.-S.; Butler, W. E.; Carter, B. S.; Chapman, P.; St
10.1101/2023.03.18.532837 — genomics — Posted on 2023-03-22
1481 Comparison of genomic-enabled cross selection criteria for the improvement of inbred line breeding populations
Danguy des Deserts, A.; Durand, N.; Servin, B.; Goudemand-Duge, E.; Alliot, J.-M.; Ruiz, D.; Charmet, G.; Elsen, J.-M.; Bouchet, S.
10.1101/2023.03.17.533166 — genetics — Posted on 2023-03-22
1483 How a highly acidic SH3 domain folds in the absence of its charged peptide target
Jaramillo- Martinez, V.; Dominguez, M. J.; Bell, G. M.; Souness, M. E.; Carhart, A. H.; Cuibus, M. A.; Masoumzadeh, E.; Lantz, B. J.; Adkins, A. J.; Latham, M. P.; Ball, K. A.; Stollar, E. J.
10.1101/2023.03.21.532811 — biophysics — Posted on 2023-03-22
1484 Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand
Holder, A.; Kolakowski, J. F.; Rosentreter, C. J.; Knuepfer, E.; Jegouzo, S.; Rosenwasser, O.; Harris, H.; Baumgaertel, L. H.; Gibson, A. J.; Werling, D.
10.1101/2023.03.20.533273 — immunology — Posted on 2023-03-22
1485 Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss
Fernando, N.; Gopalakrishnan, J.; Behensky, A.; Reich, L.; Liu, C.; Bass, V.; Bono, M.; Montgomery, W.; De Pace, R.; Mattapallil, M.; Nagarajan, V.; Brooks, S.; Maric, D.; Caspi, R.; McGavern, D.; Shih, H.-Y.
10.1101/2023.03.18.533293 — immunology — Posted on 2023-03-22
1489 Nucleolar Essential Protein 1 (Nep1): Elucidation of Enzymatic Catalysis Mechanism by Combined Molecular Dynamics Simulation and Quantum Chemical Calculations
Jedrzejewski, M.; Belza, B.; Lewandowska, I.; Sadlej, M.; Perlinska, A. P.; Augustyniak, R.; Christian, T.; Hou, Y.-M.; Kalek, M.; Sulkowska, J. I.
10.1101/2023.03.21.532383 — biophysics — Posted on 2023-03-22
1490 Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency
ZHAI, L.; Wang, Z.; Liu, F.; Xu, C.; Wang, J.; Han, H.; Xie, Q.; Zhang, W.; Zheng, Y.; Buell, A. K.; Dong, Y.
10.1101/2023.03.20.533374 — bioengineering — Posted on 2023-03-22
1491 Native American Ancestry and Pigmentation Allele Contributions to Skin Color in a Caribbean Population
Ang, K. C.; Canfield, V. A.; Foster, T. C.; Harbaugh, T. D.; Early, K. A.; Harter, R. L.; Reid, K. P.; Leong, S. L.; Kawasawa, Y. I.; Liu, D.; Hawley, J.; Cheng, K. C.
10.1101/2021.11.24.469305 — genetics — Posted on 2023-03-22
1492 A dual function of the IDA peptide in regulating cell separation and modulating plant immunity at the molecular level
Lalun, V. O.; Breiden, M.; Galindo-Trigo, S.; Smakowska-Luzan, E.; Simon, R.; Butenko, M. A.
10.1101/761346 — plant biology — Posted on 2023-03-22
1495 Phosphorylation Status Of MUS81 Is A Modifier Of Olaparib Sensitivity In BRCA2-Deficient Cells
Blandino, F.; Malacaria, E.; Figlioli, C.; Noto, A.; Pugliese, G. M.; Franchitto, A.; Pichierri, P.
10.1101/2022.08.13.503764 — cell biology — Posted on 2023-03-22
1497 Heritable microbiome variation is correlated with source environment in locally adapted maize varieties
He, X.; Wang, D.; Jiang, Y.; Li, M.; Delgado-Baquerizo, M.; McLaughlin, C.; Marcon, C.; Baer, M.; Guo, L.; Moya, Y. A. T.; von Wiren, N.; Deichmann, M.; Schaaf, G.; Piepho, H.-P.; Yang, Z.; Yang, J.; Yim, B.; Smalla, K.; Goormachtig, S.; de Vries, F. T.; Huging, H.; Sawers, R. J. H.; Reif, J. C.; Hochholdinger, F.; Chen, X.; Yu, P.
10.1101/2023.01.10.523403 — genetics — Posted on 2023-03-22
1498 Machine learning analysis of the T cell receptor repertoire identifies sequence features that predict self-reactivity
Textor, J.; Buytenhuijs, F.; Rogers, D.; Mallet Gauthier, E.; Sultan, S.; Wortel, I. M. N.; Kalies, K.; Fähnrich, A.; Pagel, R.; Melichar, H.; Westermann, J.; Mandl, J. N.
10.1101/2022.11.23.517563 — immunology — Posted on 2023-03-22
1500 Role of GD2 and its biosynthetic enzyme GD3 synthase in prostate cancer tumorigenesis
Bhat, A. M.; Mohapatra, B. C.; Luan, H.; Mushtaq, I.; Chakraborty, S.; Dutta, S.; Stock, M. D.; Meza, J. L.; Lin, M.-F.; Cook, L. M.; Corey, E.; Morrissey, C.; Coulter, D. W.; Rowley, J.; Datta, K.; Band, V.; Band, H.
10.1101/2023.03.18.533299 — cancer biology — Posted on 2023-03-22
1502 Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis
Baer, L.; Barthelson, K.; Postlethwait, J.; Adelson, D. L.; Pederson, S. M.; Lardelli, M.
10.1101/2023.03.02.530865 — genetics — Posted on 2023-03-22
1505 A Multiomic Analysis Reveals How Breast Cancers Disseminated to the Bone Marrow Acquire Aggressive Phenotypes through Tumor-Stroma Tunnels
Sinha, S.; Callow, B.; Farfel, A.; Roy, S.; Chen, S.; Rajendran, S.; Buschhaus, J.; Luker, K. E.; Ghosh, P.; Luker, G. D.
10.1101/2023.03.18.533175 — cancer biology — Posted on 2023-03-22
1507 Neural populations in the language network differ in the size of their temporal receptive windows
Regev, T. I.; Casto, C.; Hosseini, E. A.; Adamek, M.; Ritaccio, A. L.; Brunner, P.; Fedorenko, E.
10.1101/2022.12.30.522216 — neuroscience — Posted on 2023-03-21
1509 Intracellular mechanics and TBX3 expression jointly dictate the spreading mode of melanoma cells in 3D environments
Higgins, G.; Higgins, F.; Peres, J.; Lang, D. M.; Abdalrahman, T.; Zaman, M.; Prince, S.; Franz, T.
10.1101/2022.06.09.495509 — biophysics — Posted on 2023-03-21
1510 The smallest infectious substructure encoding the prion strain structural determinant revealed by spontaneous dissociation of misfolded prion protein assemblies
Bohl, J.; Moudjou, M.; Herzog, L.; Reine, F.; Sailer, F.; Klute, H.; Halgand, F.; Vand der Rest, G.; Boulard, Y.; Igel, A.; Beringue, V.; Rezaei, H.
10.1101/2023.03.21.533631 — biochemistry — Posted on 2023-03-21
1511 Mechanistic and structural insights into a divergent PLP-dependent L-enduracididine cyclase from a toxic cyanobacterium
Cordoza, J. L.; Chen, P. Y.-T.; Blaustein, L. R.; Lima, S. T.; Fiore, M. F.; Chekan, J. R.; Moore, B. S.; McKinnie, S. M. K.
10.1101/2023.03.21.533663 — biochemistry — Posted on 2023-03-21
1512 RNase R Controls Membrane Fatty Acid Composition in Streptococcus pneumoniae
Alipio, A. F.; Barria, C.; Pobre, V.; Matos, A. R.; Amblar, M.; Arraiano, C. M.; Domingues, S.
10.1101/2023.03.21.533657 — molecular biology — Posted on 2023-03-21
1513 Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice
Lum, G. R.; Hsiao, E. Y.; Ha, S. M.; Olson, C.; Blencowe, M.; Paramo, J.; Reyes, B.; Matsumoto, J.; Yang, X.; Hsiao, E.
10.1101/2023.03.17.533243 — microbiology — Posted on 2023-03-21
1514 Involvement of the putative metal efflux protein YbeX in ribosomal metabolism
Sarıgül, I.; Zukova, A.; Alparslan, E.; Pihlak, M.; Remm, S.; Tenson, T.; Maiväli, U.
10.1101/2023.03.20.533420 — microbiology — Posted on 2023-03-21
1515 Whole-body Microbiota of Newborn Calves and Their Response to Prenatal Vitamin and Mineral Supplementation
Luecke, S. M.; Holman, D. B.; Schmidt, K. N.; Gzyl, K. E.; Hurlbert, J. L.; Menezes, A. C. B.; Bochantin, K. A.; Kirsch, J. D.; Baumgaertner, F.; Sedivec, K. K.; Swanson, K. C.; Dahlen, C. R.; Amat, S.
10.1101/2023.03.21.533572 — microbiology — Posted on 2023-03-21
1516 Learning the Vector Coding of Egocentric Boundary Cells from Visual Data
Lian, Y.; Williams, S.; Alexander, A. S.; Hasselmo, M. E.; Burkitt, A. N.
10.1101/2022.01.28.478267 — neuroscience — Posted on 2023-03-21
1517 Time-resolved cryo-EM of G protein activation by a GPCR
Papasergi-Scott, M. M.; Perez-Hernandez, G.; Batebi, H.; Gao, Y.; Eskici, G.; Seven, A. B.; Panova, O.; Hilger, D.; Casiraghi, M.; He, F.; Maul, L.; Gmeiner, P.; Kobilka, B. K.; Hildebrand, P. W.; Skiniotis, G.
10.1101/2023.03.20.533387 — pharmacology and toxicology — Posted on 2023-03-21
1518 Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP
Sabri, N.; Cuneo, M. J.; Marzahn, M. R.; Lee, J.; Bouchard, J. J.; Vaithiyalingam, S.; Borgia, M. B.; Schmit, J. D.; Mittag, T.
10.1101/2023.02.11.528154 — biophysics — Posted on 2023-03-21
1519 A remarkably specific ligand reveals ghrelin O-acyltransferase interacts with extracellular peptides and exhibits unexpected cellular localization for a secretory pathway enzyme
Campana, M. B.; Davis, T. R.; Cleverdon, E. R.; Bates, M.; Krishnan, N.; Curtis, E. R.; Childs, M. D.; Pierce, M. R.; Novak, S. X.; Morales-Rodriguez, Y.; Sieburg, M.; Hehnly, H.; Luyt, L. G.; Hougland, J.
10.1101/2021.06.01.446150 — biochemistry — Posted on 2023-03-21
1520 Transcriptome profiling of the Caenorhabditis elegans intestine reveals that ELT-2 negatively and positively regulates intestinal gene expression within the context of a gene regulatory network
Williams, R. T.; King, D. C.; Mastroianni, I. R.; Hill, J. L.; Apenes, N. W.; Ramirez, G.; Miner, E. C.; Moore, A.; Coleman, K.; Osborne Nishimura, E.
10.1101/2021.08.29.457787 — genomics — Posted on 2023-03-21
1526 Age-associated Differences in the Human Lung Extracellular Matrix
Koloko Ngassie, M. L.; De Vries, M.; Borghuis, T.; Timens, W.; Sin, D. D.; Nickle, D.; Joubert, P.; Horvatovich, P.; Marko-Varga, G.; Teske, J. J.; Vonk, J. M.; Gosens, R.; Prakash, Y. S.; Burgess, J.; Brandsma, C.-A.
10.1101/2022.06.16.496465 — molecular biology — Posted on 2023-03-21
1528 The association of the RSC remodeler complex with chromatin depends on prefoldin-like Bud27 and determines nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae
Cuevas-Bermudez, A.; Martinez-Fernandez, V.; Garrido-Godino, A. I.; Pla, A. J.; Penate, X.; Martin-Exposito, M.; Gutierrez, G.; Govind, C. K.; Chavez, S.; Pelechano, V.; Navarro, F.
10.1101/2023.03.21.533665 — molecular biology — Posted on 2023-03-21
1529 SARS-CoV-2 infection activates endogenous retroviruses of the LTR69 subfamily
Arora, A.; Kolberg, J. E.; Badarinarayan, S. S.; Munot, D.; Mueller, M.; Sauter, D.; Bansal, V.
10.1101/2023.03.21.533610 — molecular biology — Posted on 2023-03-21
1531 First insights into nasal microbiome in wine tasters
Duarte Coimbra, S.; Forcina, G.; Perez Pardal, L.; Beja-Pereira, A.
10.1101/2023.03.21.533426 — microbiology — Posted on 2023-03-21
1532 Broad sialic acid usage amongst species D human adenovirus.
Mundy, R. M.; Baker, A. T.; Bates, E. A.; Cunliffe, T. G.; Teijeira-Crespo, A. L.; Moses, E.; Rizkallah, P. J.; Parker, A. L.
10.1101/2023.03.21.533702 — microbiology — Posted on 2023-03-21
1533 The RBPome of influenza A virus mRNA reveals a role for TDP-43 in viral replication
Dupont, M.; Krischuns, T.; Giai Gianetto, Q.; Paisant, S.; Bonazza, S.; Brault, J.-B.; Douche, T.; Perez-Perri, J. I.; Hentze, M. W.; Cusack, S.; Matondo, M.; Isel, C.; Courtney, D.; Naffakh, N.
10.1101/2023.03.21.533609 — microbiology — Posted on 2023-03-21
1534 Uncovering plant microbiomes using long-read metagenomic sequencing
Masuda, S.; Gan, P.; Kiguchi, Y.; Anda, M.; Sasaki, K.; Shibata, A.; Iwasaki, W.; Suda, W.; Shirasu, K.
10.1101/2023.03.20.533568 — microbiology — Posted on 2023-03-21
1536 A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia
Kaurani, L.; Islam, M. R.; Heilbronner, U.; Krüger, D. M.; Zhou, J.; Methi, A.; Strauss, J.; Pradhan, R.; Burkhardt, S.; Pena, T.; Erlebach, L.; Bühler, A.; Budde, M.; Senner, F.; Kohshour, M. O.; Schulte, E. C.; Schmauss, M.; Reininghaus, E. Z.; Juckel, G.; Kronenberg-Versteeg, D.; Delalle, I.; Odoardi, F.; Flügel, A.; Schulze, T. G.; Falkai, P.; Sananbenesi, F.; Fischer, A.
10.1101/2023.03.21.533602 — neuroscience — Posted on 2023-03-21
1538 New insights underlying the early events of dopaminergic dysfunction in Parkinson's Disease
Dela Cruz, H. L.; Dela Cruz, E. L.; Zurhellen, C. J.; York, H. T.; Baun, J. A.; Dela Cruz, J. L.; Dela Cruz, J. S.
10.1101/2020.09.27.313957 — neuroscience — Posted on 2023-03-21
1541 Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration after peripheral nerve injury
Fuentes-Flores, A.; Geronimo-Olvera, C.; Necunir-Ibarra, D. S.; Patel, S. K.; Bons, J.; Wright, M. C.; Geschwind, D.; Höke, A.; Gomez-Sanchez, J. A.; Schilling, B.; Campisi, J.; Court, F. A.
10.1101/2022.12.07.519441 — neuroscience — Posted on 2023-03-21
1543 Concussion-related disruptions to hub connectivity in the default mode network are related to symptoms and cognition
Bouchard, H. C.; Higgins, K. L.; Amadon, G. K.; Laing, J. M.; Maerlender, A.; Al-Momani, S.; Neta, M.; Savage, C. R.; Schultz, D. H.
10.1101/2023.03.07.531551 — neuroscience — Posted on 2023-03-21
1546 Astrocytes control cocaine-induced synaptic plasticity and reward through the matricellular protein hevin
Mongredien, R.; Anesio, A.; Fernandes, G. J. D.; Eagle, A. L.; Maldera, S.; Pham, C.; Vilette, A.; Bianchi, P. C.; Franco, C.; Louis, F.; Gruszczynski, C.; Betancur, C.; Erdozain, A. M.; Robison, A. J.; Boucard, A. A.; Li, D.; Cruz, F. C.; Gautron, S.; Heck, N.; Vialou, V.
10.1101/2023.03.19.533284 — neuroscience — Posted on 2023-03-21
1547 Molecular and mineral responses of corals grown under artificial Calcite Sea conditions
Conci, N.; Griesshaber, E.; Rivera, R.; Schmahl, W. W.; Vargas, S.; Wörheide, G.
10.1101/2022.02.25.481970 — paleontology — Posted on 2023-03-21
1548 Spatial omics representation and functional tissue module inference using graph Fourier transform
Chang, Y.; Liu, J.; Ma, A.; Jiang, S.; Krull, J.; Yeo, Y.; Liu, Y.; Rodig, S.; Barouch, D. H.; Fan, R.; Xu, D.; Nolan, G. P.; Li, Z.; Liu, B.; Ma, Q.
10.1101/2022.12.10.519929 — bioinformatics — Posted on 2023-03-21
1552 Using accelerometers to infer behaviour of cryptic species in the wild
Benoit, L.; Bonnot, N. C.; Debeffe, L.; Gremillet, D.; Hewison, A. J. M.; Puch, L.; Marchand, P.; Bonnet, A.; Cargnelutti, B.; Cebe, N.; Lourtet, B.; Coulon, A.; Morellet, N.
10.1101/2023.03.20.533342 — animal behavior and cognition — Posted on 2023-03-21
1553 Effects of alertness on perceptual detection and discrimination
Xu, Y.; Wokke, M.; Noreika, V.; Bareham, C.; Jagannathan, S.; Georgieva, S.; Trentin, C.; Bekinschtein, T.
10.1101/2023.03.21.533623 — animal behavior and cognition — Posted on 2023-03-21
1555 A cautionary note on quantitative measures of phenotypic convergence
Grossnickle, D. M.; Brightly, W. H.; Weaver, L. N.; Stanchak, K. E.; Roston, R. A.; Pevsner, S. K.; Stayton, C. T.; Polly, P. D.; Law, C. J.
10.1101/2022.10.18.512739 — evolutionary biology — Posted on 2023-03-21
1557 Induction of osteogenic differentiation of MSCs by GSK3beta knockdown through GSK3beta siRNAs transfection
Galitsyna, E. V.; Buianova, A. A.; Bukharova, T. B.; Krivosheeva, I. A.; Skoblov, M. Y.; Goldshtein, D. V.
10.1101/2023.03.21.533598 — molecular biology — Posted on 2023-03-21
1558 The Cytomegalovirus M35 Protein Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes by Direct Promoter Binding
Schwanke, H.; Goncalves Magalhaes, V.; Schmelz, S.; Wyler, E.; Hennig, T.; Guenther, T.; Grundhoff, A.; Doelken, L.; Landthaler, M.; van Ham, M.; Jaensch, L.; Buessow, K.; van den Heuvel, J.; Blankenfeldt, W.; Friedel, C. C.; Erhard, F.; Brinkmann, M. M.
10.1101/2023.03.21.533612 — molecular biology — Posted on 2023-03-21
1559 Replication-induced DNA secondary structures drive fork uncoupling and breakage
Williams, S. L.; Casas-Delucchi, C. S.; Raguseo, F.; Guneri, D.; Li, Y.; Minamino, M.; Fletcher, E. E.; Yeeles, J. T.; Keyser, U. F.; Waller, Z. A.; Di Antonio, M.; Coster, G.
10.1101/2022.11.18.517070 — molecular biology — Posted on 2023-03-21
1562 Fungal antigenic variation using mosaicism and reassortment of subtelomeric genes' repertoires, potentially mediated by DNA triplexes
Meier, C. S.; Pagni, M.; Richard, S.; Muhlethaler, K.; Almeida, J. M. G. C. F.; Nevez, G.; Cushion, M. T.; Calderon, E. J.; Hauser, P. M.
10.1101/2023.03.21.533526 — microbiology — Posted on 2023-03-21
1564 HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages.
Virgilio, M. C.; Disbennett, W. M.; Chen, T.; Lubow, J.; Welch, J. D.; Collins, K. L.
10.1101/2023.03.21.533528 — microbiology — Posted on 2023-03-21
1565 Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity
Kumaraswamy, M.; Riestra, A.; Flores, A.; Uchiyama, S.; Dahesh, S.; Bondsater, G.; Nilsson, V.; Chang, M.; Seo, H.; Sakoulas, G.; Nizet, V.
10.1101/2023.03.21.533661 — microbiology — Posted on 2023-03-21
1566 Partial genome characterization of a novel potentially zoonotic parapoxvirus in a horse, Finland
Virtanen, J.; Hautaniemi, M.; Dutra, L.; Pljusnin, I.; Smura, T.; Vapalahti, O.; Sironen, T.; Kant, R.; Kinnunen, P. M.
10.1101/2023.03.21.533517 — microbiology — Posted on 2023-03-21
1567 Comparative genomics of Mycoplasma feriruminatoris, a fast-growing pathogen of wild Caprinae
Baby, V.; Ambroset, C.; Gaurivaud, P.; Falquet, L.; Boury, C.; Guichoux, E.; Jores, J.; Lartigue, C.; Tardy, F.; Sirand-Pugnet, P.
10.1101/2023.03.21.533155 — microbiology — Posted on 2023-03-21
1568 RNase L activating 2'-5' oligoadenlyates bind ABCF1, -3 and Decr-1
Gowande, A. A.; Babnis, A. W.; Urban, C.; Habjan, M.; Hartmann, R.; Kranzusch, P. J.; Pichlmair, A.
10.1101/2023.03.21.532770 — microbiology — Posted on 2023-03-21
1569 The importance of cellulolytic and xylanolytic activities of Bacillus subtilis on dairy cow feed digestibility
Bonta', V.; Battelli, M.; Rama, E.; Casanova, M.; Pasotti, L.; Galassi, G.; Colombini, S.; Calvio, C.
10.1101/2023.03.20.533435 — microbiology — Posted on 2023-03-21
1571 Paying attention to natural scenes in area V1
Lazar, A.; Klein, L.; Klon-Lipok, J.; Banyai, M.; Orban, G.; Singer, W.
10.1101/2023.03.21.533636 — neuroscience — Posted on 2023-03-21
1572 ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease
Bartosch, A. M. W.; Youth, E. H. H.; Hansen, S.; Kaufman, M. E.; Xiao, H.; Koo, S. Y.; Ashok, A.; Sivakumar, S.; Soni, R. K.; Dumitrescu, L. C.; Lam, T. G.; Ropri, A. S.; Lee, A. J.; Klein, H.-U.; Vardarajan, B. N.; Bennett, D. A. J.; Young-Pearse, T.; De Jager, P. L.; Hohman, T. J.; Sproul, A. A.; Teich, A. F.
10.1101/2023.03.21.533654 — neuroscience — Posted on 2023-03-21
1577 A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements
Hayashi, M.; Gullo, M.; Senturk, G.; Di Costanzo, S.; Nagasaki, S. C.; Kageyama, R.; Imayoshi, I.; Goulding, M.; Pfaff, S. L.; Gatto, G.
10.1101/2023.03.21.533603 — neuroscience — Posted on 2023-03-21
1578 TREM2-dependent senescent microglia conserved in aging and Alzheimer's disease
Rachmian, N.; Medina, S.; Cherqui, U.; Akiva, H.; Deitch, D.; Edilbi, D.; Croese, T.; Salame, T. M.; Peralta Ramos, J. M.; Cahalon, L.; Krizhanovsky, V.; Schwartz, M.
10.1101/2023.03.20.533401 — neuroscience — Posted on 2023-03-21
1582 Bacterial genome engineering using CRISPR RNA-guided transposases
Gelsinger, D. R.; Vo, P. L. H.; Klompe, S. E.; Ronda, C.; Wang, H. H.; Sternberg, S. H.
10.1101/2023.03.18.533263 — bioengineering — Posted on 2023-03-21
1584 Nanopore adaptive sampling of a metagenomic sample derived from a human monkeypox case
Hewel, C.; Schmidt, H.; Runkel, S.; Kohnen, W.; Schweiger-Seemann, S.; Michel, A.; Bikar, S.-E.; Plachter, B.; Hankeln, T.; Linke, M.; Gerber, S.
10.1101/2023.03.21.533647 — microbiology — Posted on 2023-03-21
1585 Nanograms of SARS-CoV-2 Spike Protein Delivered by Exosomes Induce Potent Neutralization of Both Delta and Omicron Variants.
Cacciottolo, M.; Li, Y.; Nice, J. B.; LeClaire, M. J.; Twaddle, R.; Mora, C. L.; Adachi, S. Y.; Young, M.; Angeles, J.; Elliott, K.; Sun, M.
10.1101/2023.03.20.533560 — immunology — Posted on 2023-03-21
1589 Mammals achieve common neural coverage of visual scenes using distinct sampling behaviors
Samonds, J. M.; Szinte, M.; Barr, C.; Montagnini, A.; Masson, G. S.; Priebe, N. J.
10.1101/2023.03.20.533210 — neuroscience — Posted on 2023-03-21
1596 Inhibition of sensory neuron driven acute, inflammatory, and neuropathic pain using a humanised chemogenetic system
Sanchez, J. P.; Middleton, S. J.; Pattison, L. A.; Hilton, H.; Awadelkareem, M. A.; Zuberi, S. R.; Renke, M. B.; Hu, H.; Yang, X.; Clark, A. J.; Smith, E. S. J.; Bennett, D. L.
10.1101/2023.03.21.533690 — neuroscience — Posted on 2023-03-21
1600 Distinct Transcriptomic Responses to A beta plaques, Neurofibrillary Tangles, and APOE in Alzheimer's Disease
Das, S.; Li, Z.; Wachter, A.; Alla, S.; Noori, A.; Abdourahman, A.; Tamm, J. A.; Woodbury, M.; Talanian, R. V.; Biber, K.; Karran, E. H.; Hyman, B. T.; Serrano-Pozo, A.
10.1101/2023.03.20.533303 — neuroscience — Posted on 2023-03-21
1602 Age and diet modulate the insulin-sensitizing effects of exercise: a tracer-based oral glucose tolerance test
Vieira-Lara, M. A.; Reijne, A. C.; Koshian, S.; Ciapaite, J.; Abegaz, F.; Talarovicova, A.; van Dijk, T. H.; Versloot, C. J.; Bandsma, R. H. J.; Wolters, J. C.; Groen, A. K.; Reijngoud, D.-J.; van Dijk, G.; Bakker, B. M.
10.1101/2023.03.18.533083 — physiology — Posted on 2023-03-21
1605 Reproductive tactics, birth timing and the trade-off between risk avoidance and foraging in an income breeder
Benoit, L.; Morellet, N.; Bonnot, N. C.; Cargnelutti, B.; Chaval, Y.; Gaillard, J.-M.; Loison, A.; Lourtet, B.; Marchand, P.; Coulon, A.; Hewison, A. J. M.
10.1101/2023.03.20.533335 — animal behavior and cognition — Posted on 2023-03-21
1609 Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice
Lum, G. R.; Hsiao, E. Y.; Ha, S. M.; Olson, C.; Blencowe, M.; Paramo, J.; Reyes, B.; Matsumoto, J.; Yang, X.; Hsiao, E.
10.1101/2023.03.17.533243 — microbiology — Posted on 2023-03-21
1610 Elevated CD153 Expression on Aged T Follicular Helper Cell is Vital for B cell Responses
Thomas, A. L.; Wayman, J. A.; Almanan, M.; Bejjani, A. T.; Miraldi, E.; Chougnet, C. A.; Hildeman, D.
10.1101/2023.03.17.533214 — immunology — Posted on 2023-03-21
1611 A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation
Susa, K. J.; Bradshaw, G. A.; Eisert, R. J.; Schillling, C. M.; Kalocsay, M.; Blacklow, S. C.; Kruse, A. C.
10.1101/2023.03.17.533227 — immunology — Posted on 2023-03-21
1612 Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium
Dunlap, G. S.; Wagner, A.; Meednu, N.; Zhang, F.; Jonsson, A. H.; Wei, K.; Sakaue, S.; Nathan, A.; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (A, ; Bykerk, V. P.; Donlin, L. T.; Goodman, S. M.; Firestein, G. S.; Boyle, D. L.; Holers, V. M.; Moreland, L. W.; Tabechian, D.; Pitzalis, C.; Filer, A.; Raychaudhuri, S.; Brenner, M. B.; Rao, D. A.; Anolik, J.
10.1101/2023.03.18.533282 — immunology — Posted on 2023-03-21
1620 Uncovering the Environmental Conditions Required for Phyllachora maydis Infection and Tar Spot Development on Corn in the United States for Use as Predictive Models for Future Epidemics
Webster, R. W.; Nicolli, C.; Allen, T. W.; Bish, M. D.; Bissonette, K.; Check, J. C.; Chilvers, M. I.; Kleczewski, N.; Mueller, B. D.; Price, P. P.; Paul, P.; Robertson, A. E.; Ross, T. J.; Schmidt, C.; Schmidt, R.; Schmidt, T.; Shim, S.; Telenko, D. E. P.; Wise, K.; Smith, D. L.
10.1101/2023.03.18.533264 — plant biology — Posted on 2023-03-21
1623 Multiomic Analysis of Intercellular Communication through Tumor-Stroma Tunnels in Breast Cancers
Sinha, S.; Callow, B.; Farfel, A.; Roy, S.; Chen, S.; Rajendran, S.; Buschhaus, J.; Luker, K. E.; Ghosh, P.; Luker, G. D.
10.1101/2023.03.18.533175 — cancer biology — Posted on 2023-03-21
1624 IGF2BP1 induces high-risk neuroblastoma and forms a druggable feedforward loop with MYCN promoting 17q oncogene expression
Hagemann, S.; Misiak, D.; Bell, J. L.; Fuchs, T.; Lederer, M. I.; Bley, N.; Haemmerle, M.; Ghazy, E.; Sippl, W.; Schulte, J. H.; Huettelmaier, S.
10.1101/2023.03.18.533148 — cancer biology — Posted on 2023-03-21
1629 Co-segregation of recombinant chromatids maintains genome-wide heterozygosity in an asexual nematode
Blanc, C.; saclier, N.; Le Faou, E.; Marie-Orleach, L.; Wenger, E.; Diblasi, C.; Glemin, S.; Galtier, N.; Delattre, M.
10.1101/2023.03.17.533182 — evolutionary biology — Posted on 2023-03-21
1630 Fungal organic acid uptake of mineral derived K is dependent on distance from carbon hotspot
Bhattacharjee, A.; Velickovic, D.; Richardson, J. A.; Couvillion, S. P.; Vandergrift, G. W.; Qafoku, O.; Taylor, M. J.; Jansson, J. K.; Hofmockel, K. S.; Anderton, C. R.
10.1101/2023.03.17.533228 — ecology — Posted on 2023-03-21
1631 Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells
Sanmarco, L. M.; Rone, J. M.; Polonio, C. M.; Giovannoni, F.; Fernandez Lahore, G.; Ferrara, K.; Gutierrez-Vazquez, C.; Li, N.; Sokolovska, A.; Plasencia, A.; Faust Akl, C.; Nanda, P.; Heck, E. S.; Li, Z.; Lee, H.-G.; Chao, C.-C.; Rejano-Gordillo, C. M.; Fonseca-Castro, P. H.; Illouz, T.; Linnerbauer, M.; Kenison, J. E.; Barilla, R. M.; Farrenkopf, D.; Piester, G.; Dailey, L.; Kuchroo, V. K.; Hava, D.; Wheeler, M. A.; Clish, C.; Nowarski, R.; Balsa, E.; Lora, J. M.; Quintana, F. J.
10.1101/2023.03.17.532101 — immunology — Posted on 2023-03-21
1632 How total mRNA influences cell growth
Calabrese, L.; Ciandrini, L.; Cosentino Lagomarsino, M.
10.1101/2023.03.17.533181 — systems biology — Posted on 2023-03-21
1635 Correlative Imaging of 3D Cell Culture on Opaque Bioscaffolds for Tissue Engineering Applications
Sawyer, M.; Eixenberger, J.; Nielson, O.; Manzi, J.; Montenegro-Brown, R.; Subbaraman, H.; Estrada, D.
10.1101/2023.03.17.533202 — bioengineering — Posted on 2023-03-21
1636 Reduction of cortical pulling at mitotic entry facilitates aster centration
Rosfelter, A.; de Labbey, G.; Chenevert, J.; Dumollard, R.; Schaub, S.; Machaty, Z.; Besnardeau, L.; Hebras, C.; Turlier, H.; Burgess, D.; mcdougall, a.
10.1101/2023.03.21.533625 — cell biology — Posted on 2023-03-21
1637 A phase-field model for non-small cell lung cancer under the effects of immunotherapy
Wagner, A.; Schlicke, P.; Fritz, M.; Kuttler, C.; Oden, J. T.; Schumann, C.; Wohlmuth, B.
10.1101/2023.03.20.533400 — cell biology — Posted on 2023-03-21
1639 Matters Arising: FBXO38 does not control PD-1 stability
Dibus, N.; Salyova, E.; Kolarova, K.; Pagano, M.; Stepanek, O.; Cermak, L.
10.1101/2023.03.19.531556 — cell biology — Posted on 2023-03-21
1642 AN ARTIFICIAL INTELLIGENCE FOR RAPID IN-LINE LABEL-FREE HUMAN PLURIPOTENT STEM CELL COUNTING AND QUALITY ASSESSMENT
Ragunton, B. L.; Van Buskirk, S.; Wakefield, D.; Randive, N.; Pipathsouk, A.; Pei, B.; Zhou, H.; Yamawaki, T. M.; Berke, M.; Li, C.-M. K.; Hale, C.; Wang, S.; Chambers, S.
10.1101/2023.03.20.533543 — cell biology — Posted on 2023-03-21
1643 A hierarchical strategy to decipher protein dynamics in vivo with chemical cross-linking mass spectrometry
Zhang, B.; Gong, Z.; Zhao, L.; An, Y.; Gao, H.; Chen, J.; Liang, Z.; Liu, M.; Zhang, Y.; Zhao, Q.; Zhang, L.
10.1101/2023.03.21.533582 — cell biology — Posted on 2023-03-21
1644 LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration
Deng, Y.; Zhao, Z.; Sheldon, M.; Zhao, Y.; Teng, H.; Martinez, C.; Zhang, J.; Lin, C.; Sun, Y.; Yao, F.; Zhu, H.; Ma, L.
10.1101/2023.03.18.533289 — cell biology — Posted on 2023-03-21
1645 Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease
Wang, Z.; Zhu, S.; Jia, Y.; Wang, Y.; Kubota, N.; Fujiwara, N.; Gordillo, R.; Lewis, C.; Zhu, M.; Sharma, T.; Li, L.; Zeng, Q.; Lin, Y.-H.; Hsieh, M.-H.; Gopal, P.; Wang, T.; Hoare, M.; Campbell, P.; Hoshida, Y.; Zhu, H.
10.1101/2023.03.20.533505 — cell biology — Posted on 2023-03-21
1649 Protein supersaturation powers innate immune signaling
Rodriguez Gama, A.; Miller, T.; Lange, J. J.; Wu, J.; Song, X.; Venkatesan, S.; Unruh, J.; Bradford, W.; Halfmann, R.
10.1101/2023.03.20.533581 — immunology — Posted on 2023-03-21
1651 Pathologic polyglutamine aggregation begins with a self-poisoning polymer crystal
Kandola, T.; Venkatesan, S.; Zhang, J.; Lerbakken, B. T.; Von Schulze, A.; Blanck, J. F.; Wu, J.; Unruh, J. R.; Berry, P.; Lange, J. J.; Box, A. C.; Cook, M.; Sagui, C.; Halfmann, R.
10.1101/2023.03.20.533418 — biophysics — Posted on 2023-03-21
1652 Alpha-synuclein oligomers displace monomeric alpha-synuclein from lipid membranes
Sneideriene, G.; Czekalska, M. A.; Xu, C. K.; Jayaram, A.; Krainer, G.; Arter, W. E.; Peter, Q.; Castellana-Cruz, M.; Saar, K. L.; Levin, A.; Mueller, T.; Fiedler, S.; Devenish, S. R. A.; Fiegler, H.; Kumita, J. R.; Knowles, T.
10.1101/2023.03.21.533646 — biophysics — Posted on 2023-03-21
1654 On-grid purification of electron microscopy samples via a 3D-printed flow-cell
Ramlaul, K.; Feng, Z.; Canavan, C.; de Martin Garrido, N.; Carreno, D.; Crone, M.; Jensen, K. E.; Li, B.; Barnet, H.; Riglar, D. T.; Miller, D.; Freemont, P. S.; Aylett, C. H. S.
10.1101/2023.03.17.533159 — biophysics — Posted on 2023-03-21
1655 Sculpting DNA-based synthetic cells through phase separation and phase-targeted activity
Malouf, L.; Tanase, D. A.; Fabrini, G.; Paez-Perez, M.; Leathers, A.; Booth, M. J.; Di Michele, L.
10.1101/2023.03.17.533162 — biophysics — Posted on 2023-03-21
1659 Cell type-specific and disease-associated eQTL in the human lung
Natri, H. M.; Del Azodi, C. B.; Peter, L.; Taylor, C. J.; Chugh, S.; Kendle, R.; Chung, M.-i.; Flaherty, D. K.; Matlock, B. K.; Calvi, C. L.; Blackwell, T. S.; Ware, L. B.; Bacchetta, M.; Walia, R.; Shaver, C. M.; Kropski, J. A.; McCarthy, D. J.; Banovich, N. E.
10.1101/2023.03.17.533161 — genomics — Posted on 2023-03-21
1660 The annotation and function of the Parkinson's and Gaucher disease-linked gene GBA1 has been concealed by its protein-coding pseudogene GBAP1
Gustavsson, E. K.; Sethi, S.; Gao, Y.; Brenton, J.; Garcia Ruiz, S.; Zhang, D.; Garza, R.; Reynolds, R. H.; Evans, J. R.; Chen, Z.; Grant-Peters, M.; MacPherson, H.; Montgomery, K.; Dore, R.; Wernick, A. I.; Arber, C.; Wray, S.; Gandhi, S.; Esselborn, J.; Blauwendraat, C.; Douse, C. H.; Adami, A.; Atacho, D. A. M.; Kouli, A.; Quaegebeur, A.; Barker, R. A.; Englund, E.; Platt, F. M.; Jakobsson, J.; Wood, N. W.; Houlden, H.; Saini, H.; Bento, C. F.; Hardy, J.; Ryten, M.
10.1101/2022.10.21.513169 — genetics — Posted on 2023-03-21
1662 Finite Sample Adjustments for Average Equivalence Testing
Boulaguiem, Y.; Quartier, J.; Lapteva, M.; Kalia, Y. N.; Victoria-Feser, M.-P.; Guerrier, S.; Couturier, D.-L.
10.1101/2023.03.11.532179 — pharmacology and toxicology — Posted on 2023-03-21
1664 T-ALL Proliferation Relies on Glutamine Uptake and EAAT1-dependent Conversion of Glutamine to Aspartate and Nucleotides
Stanulovic, V. S.; Al Omair, S.; Reed, M. A. C.; Potluri, S.; Roberts, J.; Perry, T. A.; Sarkar, S.; Pratt, G. E.; Gunther, U. L.; Ludwig, C.; Hoogenkamp, M.
10.1101/2020.02.08.939694 — cancer biology — Posted on 2023-03-21
1666 Long read proteogenomics to connect disease-associated sQTLs to the protein isoform effectors of disease
Abood, A.; Mesner, L. D.; Jefferey, E. D.; Murali, M.; Lehe, M.; Saquing, J.; Farber, C.; Sheynkman, G. M.
10.1101/2023.03.17.531557 — bioinformatics — Posted on 2023-03-21
1669 Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling
Chaiamarit, T.; Verhelle, A.; Chassefeyre, R.; Shukla, N.; Weiser Novak, S.; Andrade, L. R.; Manor, U.; Encalada, S. E.
10.1101/2023.03.19.533383 — cell biology — Posted on 2023-03-21
1670 Neural correlates of object-extracted relative clause processing across Englishand Chinese
Dunagan, D.; Stanojevic, M.; Coavoux, M.; Zhang, S.; Bhattasali, S.; Li, J.; Brennan, J.; Hale, J. T.
10.1101/2022.09.12.507571 — neuroscience — Posted on 2023-03-21
1673 TREM2-dependent senescent microglia conserved in aging and Alzheimer's disease
Rachmian, N.; Medina, S.; Cherqui, U.; Akiva, H.; Deitch, D.; Edilbi, D.; Croese, T.; Salame, T. M.; Peralta Ramos, J. M.; Cahalon, L.; Krizhanovsky, V.; Schwartz, M.
10.1101/2023.03.20.533401 — neuroscience — Posted on 2023-03-21
1674 Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons
Rankin, G.; Chirila, A. M.; Emanuel, A. J.; Zhang, Z.; Woolf, C. J.; Drugowitsch, J.; Ginty, D. D.
10.1101/2023.03.20.533541 — neuroscience — Posted on 2023-03-21
1677 Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer
Maurer, H. C.; Curiel-Garcia, A.; Holmstrom, S.; Laise, P.; Palermo, C. F.; Sastra, S. A.; Andren, A.; Li, Z.; LeLarge, T.; Sagalovskiy, I.; Ross, D. R.; Rosarioo, V.; Lu, K.; Ferraiuolo, E.; Spinosa, N.; Wong, W.; Shaw, K.; Chabot, J. A.; Genkinger, J.; Hibshoosh, H.; Manji, G. A.; Iuga, A.; Schmid, R. M.; Badgley, M. A.; Johnson, K.; Califano, A.; Lyssiotis, C.; Olive, K. P.
10.1101/2023.03.19.533333 — cancer biology — Posted on 2023-03-21
1678 IFITM3 blocks influenza virus entry by sorting lipids and stabilizing hemifusion
Klein, S.; Golani, G.; Lolicato, F.; Lahr, C.; Beyer, D.; Herrmann, A.; Wachsmuth-Melm, M.; Reddmann, N.; Brecht, R.; Hosseinzadeh, M.; Kolovou, A.; Makroczyova, J.; Peterl, S.; Schorb, M.; Schwab, Y.; Bruegger, B.; Nickel, W.; Schwarz, U. S.; Chlanda, P.
10.1101/2022.09.01.506185 — molecular biology — Posted on 2023-03-21
1679 Tuft cell-derived acetylcholine regulates epithelial fluid secretion
Billipp, T. E.; Fung, C.; Webeck, L. M.; Sargent, D. B.; Gologorsky, M. B.; McDaniel, M. M.; Kasal, D. N.; McGinty, J. W.; Barrow, K. A.; Rich, L. M.; Barilli, A.; Sabat, M.; Debley, J. S.; Myers, R.; Howitt, M. R.; von Moltke, J.
10.1101/2023.03.17.533208 — immunology — Posted on 2023-03-21
1681 Time-resolved cryo-EM of G protein activation by a GPCR
Papasergi-Scott, M. M.; Perez-Hernnadez, G.; Batebi, H.; Gao, Y.; Eskici, G.; Seven, A. B.; Panova, O.; Hilger, D.; Casiraghi, M.; He, F.; Maul, L.; Gmeiner, P.; Kobilka, B. K.; Hildebrand, P. W.; Skiniotis, G.
10.1101/2023.03.20.533387 — physiology — Posted on 2023-03-21
1686 Adaptive evolution in virulence effectors of the rice blast fungus Pyricularia oryzae
Le Naour--Vernet, M.; Charriat, F.; Gracy, J.; Cros-Arteil, S.; Ravel, S.; Veillet, F.; Meusnier, I.; Padilla, A.; Kroj, T.; Cesari, S.; Gladieux, P.
10.1101/2023.03.16.532886 — evolutionary biology — Posted on 2023-03-21
1687 WFA-GPU: Gap-affine pairwise alignment using GPUs
Aguado-Puig, Q.; Doblas, M.; Moure, J. C.; Espinosa, A.; Matzoros, C.; Marco-Sola, S.; Moreto, M.
10.1101/2022.04.18.488374 — bioinformatics — Posted on 2023-03-21
1689 B12-dependent virioplankton demonstrate interseasonal dynamics and associate with a diversity of pelagic bacterioplankton
Wu, L.-Y.; Piedade, G. J.; Moore, R. M.; Harrison, A. O.; Martins, A. M.; Bidle, K. D.; Polson, S. W.; Sakowski, E.; Nissimov, J. I.; Dums, J. T.; Ferrell, B. D.; Wommack, K. E.
10.1101/2023.03.13.532061 — ecology — Posted on 2023-03-21
1691 Meiotic prophase length modulates Tel1-dependent DNA double-strand break interference
Ruiz, L. M. L.; Neale, M. J.; Johnson, D.; Gittens, W. H.; Brown, G.; Allison, R. M.
10.1101/2023.03.20.533494 — molecular biology — Posted on 2023-03-21
1692 FUSDelta14 mutation impairs normal brain development and causes systemic metabolic alterations
Godoy-Corchuelo, J. M.; Ali, Z.; Martins-Bach, A. B.; Garcia-Toledo, I.; Fernandez-Beltran, L. C.; Nair, R. R.; Spring, S.; Nieman, B. J.; Jimenez-Coca, I.; Bains, R. S.; Forrest, H.; Lerch, J. P.; Miller, K.; Fisher, E. M. C.; Cunningham, T. J.; Corrochano, S.
10.1101/2023.02.24.529858 — neuroscience — Posted on 2023-03-21
1693 PPML-Omics: a Privacy-Preserving federated Machine Learning method protects patients' privacy in omic data
Zhou, J.; Chen, S.; Wu, Y.; Li, H.; Zhang, B.; Zhou, L.; Hu, Y.; Xiang, Z.; Li, Z.; Chen, N.; Han, W.; Wang, D.; Gao, X.
10.1101/2022.03.23.485485 — bioinformatics — Posted on 2023-03-21
1694 Surveillance of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential
Tan, C.; Trew, J.; Peacock, T. P.; Mok, K.; Hart, C.; Lau, K.; Ni, D.; Orme, D.; Ransome, E.; Pearse, W.; Coleman, C.; Bailey, D.; Thakur, N.; Quantrill, J.; Sukhova, K.; Richard, D.; Kahane, L.; Woodward, G.; Bell, T.; Worledge, L.; Nunez-Mino, J.; Barclay, W. S.; van Dorp, L.; Balloux, F.; Savolainen, V.
10.1101/2023.01.17.524183 — genomics — Posted on 2023-03-21
1695 Functional convergence underground? The scale-dependency of community assembly processes in European cave spiders
Mammola, S.; Graco-Roza, C.; Ballarin, F.; Hesselberg, T.; Isaia, M.; Lunghi, E.; Mouron, S.; Pavlek, M.; Tolve, M.; Cardoso, P.
10.1101/2023.03.17.533085 — ecology — Posted on 2023-03-21
1699 Can hubs of the human connectome be identified consistently with diffusion MRI?
Gajwani, M.; Oldham, S. J.; Pang, J. C.; Arnatkeviciute, A.; Tiego, J.; Bellgrove, M. A.; Fornito, A.
10.1101/2022.12.21.521366 — neuroscience — Posted on 2023-03-21
1701 A methyl-seq tool to capture genomic imprinted loci
Hubert, J.-N.; Iannuccelli, N.; Cabau, C.; Jacomet, E.; Billon, Y.; Serre, R.-F.; Vandecasteele, C.; Donnadieu, C.; Demars, J.
10.1101/2023.02.21.529206 — genomics — Posted on 2023-03-21
1702 Hexokinase 1 forms rings that constrict mitochondria during energy stress
Pilic, J.; Gottschalk, B.; Bourgeois, B.; Koshenov, Z.; Oflaz, F. E.; Erdogan, Y. C.; Shoshan-Barmatz, V.; Madl, T.; Graier, W. F.; Malli, R.
10.1101/2023.03.20.533440 — cell biology — Posted on 2023-03-21
1706 Sustained activation in basal ganglia and cerebellum after repetitive movement in a non-task-specific dystonia
Kuster, J. K.; Levenstein, J. M.; Waugh, J.; Multhaupt-Buell, T. J.; Lee, M. J.; Kim, B. W.; Pagnacco, G.; Makhlouf, M. L.; Sudarsky, L. R.; Breiter, H. C.; Sharma, N.; Blood, A. J.
10.1101/2023.03.19.533030 — neuroscience — Posted on 2023-03-21
1708 Spatial and single-cell transcriptomics reveal neuron-astrocyte interplay in long-term memory
Sun, W.; Liu, Z.; Jiang, X.; Chen, M. B.; Dong, H.; Liu, J.; Sudhof, T. C.; Quake, S. R.
10.1101/2023.03.20.533566 — neuroscience — Posted on 2023-03-21
1709 Phenotypic, genomic, and transcriptomic heterogeneity in a pancreatic cancer cell line
Xie, G.; Usman, O. H.; Kumar, S.; Patel, D.; Kavanaugh, M.; Wang, Y. J.; Irianto, J.
10.1101/2022.11.11.516211 — cancer biology — Posted on 2023-03-20
1710 Accelerated Dynamic Time Warping on GPU forSelective Nanopore Sequencing
Sadasivan, H.; Stiffler, D.; Tirumala, A.; Israeli, J.; Narayanasamy, S.
10.1101/2023.03.05.531225 — bioinformatics — Posted on 2023-03-20
1711 A molecular glue approach to control the half-life of CRISPR-based technologies
Sreekanth, V.; Jan, M.; Zhao, K. T.; Lim, D.; Davis, J. R.; McConkey, M.; Kovalcik, V.; Barkal, S.; Law, B. K.; Fife, J.; Tian, R.; Vinyard, M. E.; Becerra, B.; Kampmann, M. E.; Sherwood, R. I.; Pinello, L.; Liu, D. R.; Ebert, B. L.; Choudhary, A.
10.1101/2023.03.12.531757 — bioengineering — Posted on 2023-03-20
1712 Inter-organelle crosstalk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress
Kuna, R. S.; Kumar, A.; Wessendorf-Rodriguez, K. A.; Galvez, H.; Green, C. R.; McGregor, G. H.; Cordes, T.; Shaw, R. J.; Svensson, R. U.; Metallo, C.
10.1101/2022.09.24.509326 — biochemistry — Posted on 2023-03-20
1713 Rad5 and Rad51 act at telomeres through two partially distinct pathways
Henninger, E. E.; Jolivet, P.; Berardi, P.; Fallet, E.; Benmounah, M.; Zeinoun, B.; Charvin, G.; Xu, Z.; Mattarocci, S.; Teixeira, M. T.
10.1101/2020.08.27.269621 — molecular biology — Posted on 2023-03-20
1714 Meiotic prophase length modulates Tel1-dependent DNA double-strand break interference
Ruiz, L. M. L.; Neale, M. J.; Johnson, D.; Gittens, W. H.; Brown, G.; Allison, R. M.
10.1101/2023.03.20.533494 — molecular biology — Posted on 2023-03-20
1715 Enhancers that regulate TNF gene transcription in human macrophages in response to TLR3 stimulation
Gao, J.; Li, Y.; Zhao, D.; Guan, X.; Motsinger, K.; Scott-Browne, J.; Chu, H. W.; Huang, H.
10.1101/2022.06.13.496019 — immunology — Posted on 2023-03-20
1716 Transport Pathways and Kinetics of Cerebrospinal Fluid Tracers in Mouse Brain Observed by Dynamic Contrast-Enhanced MRI
Zhu, Y.; Wang, G.; Kolluru, C.; Gu, Y.; Gao, H.; Zhang, J.; Wang, Y.; Wilson, D. L.; Zhu, X.; Flask, C. A.; Yu, X.
10.1101/2022.11.03.515111 — neuroscience — Posted on 2023-03-20
1717 Type I interferon responsive microglia shape cortical development and behavior
Escoubas, C. C.; Dorman, L. C.; Nguyen, P. T.; Lagares-Linares, C.; Nakajo, H.; Anderson, S. R.; Cuevas, B.; Vainchtein, I. D.; Silva, N. J.; Xiao, Y.; Lidsky, P. V.; Wang, E. Y.; Taloma, S. E.; Nakao-Inoue, H.; Schwer, B. J.; Andino, R.; Nowakowski, T. J.; Molofsky, A. V.
10.1101/2021.04.29.441889 — neuroscience — Posted on 2023-03-20
1718 New insights underlying the early events of dopaminergic dysfunction in Parkinson's Disease
Dela Cruz, H. L.; Dela Cruz, E. L.; Zurhellen, C. J.; York, H. T.; Baun, J. A.; Dela Cruz, J. L.; Dela Cruz, J. S.
10.1101/2020.09.27.313957 — neuroscience — Posted on 2023-03-20
1719 Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of The Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential
Sans, M.; Makino, Y.; Min, J.; Rajapakshe, K. I.; Yip-Schneider, M.; Schmidt, C. M.; Hurd, M. W.; Burks, J. K.; Gomez, J. A.; Thege, F. I.; Fahrmann, J.; Wolff, R. A.; Kim, M. P.; Guerrero, P. A.; Maitra, A.
10.1101/2022.10.19.512773 — cancer biology — Posted on 2023-03-20
1720 Tumour Extracellular Vesicles Induce Neutrophil Extracellular Traps To Promote Lymph Node Metastasis
SU, X.; Brassard, A.; Bartolomucci, A.; Dhoparee-Doomah, I.; Qiu, Q.; Tsering, T.; Rohanizadeh, R.; Koufos, O.; Giannias, B.; Bourdeau, F.; Feng, L.; Leo, S.; Sangwan, V.; Tankel, J.; Quail, D.; Spicer, J.; Burnier, J. V.; Bailey, S. D.; Ferri, L.; Cools-Lartigue, J.
10.1101/2023.03.13.532413 — cancer biology — Posted on 2023-03-20
1721 De novo identification of universal cell mechanics gene signatures
Urbanska, M.; Ge, Y.; Winzi, M.; Abuhattum, S.; Ali, S. S.; Herbig, M.; Kraeter, M.; Toepfner, N.; Durgan, J.; Florey, O.; Dori, M.; Calegari, F.; Lolo, F.-N.; del Pozo, M. A.; Taubenberger, A.; Cannistraci, C. V.; Guck, J.
10.1101/2021.04.26.441418 — biophysics — Posted on 2023-03-20
1724 Tenascin-C activation of lung fibroblasts in a 3D synthetic lung extracellular matrix mimic
Kundu, A. N.; Dougan, C. E.; Mahmoud, S.; Kilic, A.; Panagiotou, A.; Irakoze, N.; Richbourg, N.; Peyton, S. R.
10.1101/2023.02.24.529926 — bioengineering — Posted on 2023-03-20
1729 Adrenal extramedullary hematopoiesis as an inducible model of the adult hematopoietic niche
Schyrr, F.; Alonso-Calleja, A.; Vijaykumar, A.; Gebhard, S.; Sarkis, R.; Lopes, S. F.; Oggier, A.; De Leval, L.; Nombela-Arrieta, C.; Naveiras, O.
10.1101/2023.03.15.531679 — cell biology — Posted on 2023-03-20
1731 DNA virus BdDV-1 of the amphibian pathogen Batrachochytrium dendrobatidis is associated with hypervirulence
Clemons, R.; Yacoub, M.; Faust, E.; Toledo, L. F.; Jenkinson, T. S.; Kalinka, E.; Fritz-Laylin, L. K.; James, T. Y.; Stajich, J. E.
10.1101/2023.03.16.532857 — microbiology — Posted on 2023-03-20
1732 Metabolic influence of core ciliates within the rumen microbiome
Andersen, T. O.; Altshuler, I.; de Leon, A. V. P.; Walter, J.; McGovern, E.; Keogh, K.; Martin, C.; Bernard, L.; Morgavi, D. P.; Park, T.; Li, Z.; Jiang, Y.; Firkins, J. L.; Yu, Z.; Hvidsten, T. R.; Waters, S. M.; Popova, M.; Arntzen, M.; Hagen, L. H.; Pope, P. B.
10.1101/2022.06.22.497163 — microbiology — Posted on 2023-03-20
1733 Structured connectivity in the output of the cerebellar cortex
Gruver, K. M.; Jiao, J. W. Y.; Fields, E.; Song, S.; Sjostrom, P. J.; Watt, A. J.
10.1101/2023.03.17.533173 — neuroscience — Posted on 2023-03-20
1734 Profiling intra- and inter-individual differences in child and adolescent brain development
Bottenhorn, K. L.; Cardenas-Iniguez, C.; Mills, K. L.; Laird, A. R.; Herting, M. M.
10.1101/2022.12.19.521089 — neuroscience — Posted on 2023-03-20
1735 Neuromuscular Basis of Drosophila larval escape behavior
Cooney, P. C.; Li, W.; Huang, Y.; Hormigo, R.; Tabachnik, T.; Hillman, E. M. C.; Grueber, W. B.; Zarin, A. A.
10.1101/2023.02.01.526733 — neuroscience — Posted on 2023-03-20
1737 Structure of a fungal 1,3-β-glucan synthase
Zhao, C.-R.; You, Z.-L.; Chen, D.-d.; Hang, J.; Wang, Z.-B.; Wang, L.-X.; Zhao, P.; Qiao, J.; Yun, C.-H.; Bai, L.
10.1101/2023.03.19.532754 — biophysics — Posted on 2023-03-20
1740 Flexible and site-specific manipulation of histones in live animals
Finkin-Groner, E.; Al-Kachak, A.; Agustinus, A. S.; Bastle, R.; Lepack, A.; Lyu, Y.; Maze, I.; David, Y.
10.1101/2023.03.19.533378 — biochemistry — Posted on 2023-03-20
1741 Calculation of ATP production rates using the Seahorse XF Analyzer
Desousa, B. R.; Kim, K. K. O.; Jones, A. E.; Ball, A. B.; Hsieh, W. Y.; Swain, P.; Morrow, D. H.; Ferrick, D. A.; Brownstein, A. J.; Shirihai, O. S.; Neilson, A.; Nathanson, D. A.; Rogers, G. W.; Dranka, B. P.; Murphy, A. N.; Affourtit, C.; Bensinger, S. J.; Stiles, L.; Romero, N.; Divakaruni, A. S.
10.1101/2022.04.16.488523 — biochemistry — Posted on 2023-03-20
1743 Bacterial c-di-GMP plays a key role in the evolution of host-association
Obeng, N.; Czerwinski, A.; Schuetz, D.; Michels, J.; Leipert, J.; Bansept, F.; Schultheiss, T.; Kemlein, M.; Fuss, J.; Tholey, A.; Traulsen, A.; Schulenburg, H.
10.1101/2023.03.20.533436 — evolutionary biology — Posted on 2023-03-20
1745 Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
Al Khatib, I.; Deng, J.; Lei, Y.; Torres-Odio, S.; Rojas, G. R.; Newman, L. E.; Chung, B. K.; Symes, S. A.; Zhang, H.; Huang, S.-y. N.; Pommier, Y.; Khan, A.; Shadel, G. S.; West, P.; Gibson, W.; Shutt, T.
10.1101/2022.03.08.483326 — cell biology — Posted on 2023-03-20
1748 Long non-coding RNAs contribute to DNA damage resistance in Arabidopsis thaliana
Durut, N.; Kornienko, A. E.; Schmidt, H. A.; Lettner, N.; Dona, M.; Nordborg, M.; Mittelsten Scheid, O.
10.1101/2023.03.20.533408 — molecular biology — Posted on 2023-03-20
1749 Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo
Zhang, H.; Kelly, K.; Lee, J.; Echeverria, D.; Cooper, D.; Panwala, R.; Chen, Z.; Gaston, N.; Newby, G. A.; Xie, J.; Liu, D. R.; Gao, G.; Wolfe, S. A.; Khvorova, A.; Watts, J. K.; Sontheimer, E. J.
10.1101/2023.03.20.533459 — molecular biology — Posted on 2023-03-20
1752 Characteristics of the rumen virome in Japanese cattle
Sato, Y.; Takebe, H.; Tominaga, K.; Yasuda, J.; Kumagai, H.; Hirooka, H.; Yoshida, T.
10.1101/2023.03.20.532305 — microbiology — Posted on 2023-03-20
1753 A reproducible enteric phage community improves blood glucose regulation in an obesity mouse model
Mao, X.; Larsen, S. B.; Zachariassen, L. S. F.; Brunse, A.; Adamberg, S.; Castro-Mejia, J. L.; Adamberg, K.; Nielsen, D. S.; Hansen, A. K.; Hansen, C. H. F.; Rasmussen, T. S.
10.1101/2023.03.20.532903 — microbiology — Posted on 2023-03-20
1756 Using LanM Enzymes to Modify Glucagon-Like Peptides 1 and 2 in E.coli
Kjeldgaard Larsen, C.; Lindquist, P.; Rosenkilde, M.; Glendorf, T.; Ravn Madsen, A.; Haselmann, K.; Olesen, K.; Bank Kodal, A. L.; Torring, T.
10.1101/2023.03.20.532734 — synthetic biology — Posted on 2023-03-20
1757 Genomic adaptation underlies nutrient-driven reprogramming in the malaria-causing parasite
Li, Q.; Vetter, L.; Sahin, C.; Vegvari, A.; Ribacke, U.; Wahlgren, M.; Larsson, O.; Chan, S. C. L.
10.1101/2023.03.20.533258 — microbiology — Posted on 2023-03-20
1761 Gain without pain: Adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vector
Jaeger, A. S.; Marano, J.; Riemersma, K.; Castaneda, D.; Pritchard, E.; Pritchard, J.; Bohm, E. K.; Bacenzas, J. J.; O'Connor, S. L.; Weger-Lucarelli, J.; Friedrich, T. C.; Aliota, M.
10.1101/2023.03.20.533515 — microbiology — Posted on 2023-03-20
1767 Genetic and Environmental interactions contribute to immune variation in rewilded mice
Oyesola, O. O.; Downie, A. E.; Howard, N.; Barre, R. S.; Kiwanuka, K. N.; Chen, Y.-H.; Menezes, A.; Lee, S. C.; Devlin, C.; Mondragon-Palomino, O.; Silva Souza, C. O.; Herrmann, C.; Koralov, S. B.; Cadwell, K.; Graham, A. L. B.; Loke, P.
10.1101/2023.03.17.533121 — immunology — Posted on 2023-03-20
1768 Optimized two-color single-molecule tracking of fast-diffusing membrane receptors
Schirripa Spagnolo, C.; Moscardini, A.; Amodeo, R.; Beltram, F.; Luin, S.
10.1101/2023.03.17.533099 — biophysics — Posted on 2023-03-20
1771 Abnormal weather drives disease outbreaks in wild and agricultural plants
Kirk, D.; Cohen, J.; Nguyen, V.; Childs, M. L.; Farner, J. E.; Davies, T. J.; Flory, S. L.; Rohr, J. R.; O'Connor, M. I.; Mordecai, E. A.
10.1101/2023.03.17.533130 — ecology — Posted on 2023-03-20
1772 Taxonomic distribution of metabolic functions underpins nutrient cycling in Trichodesmium consortia
Koedooder, C.; Zhang, F.; Wang, S.; Haley, S. T.; Tolic, N.; Nicora, C. D.; Basu, S.; Gledhill, M.; Boiteau, R.; Dyhrman, S.; Rubin-Blum, M.; Shaked, Y.
10.1101/2023.03.15.532517 — microbiology — Posted on 2023-03-20
1775 Integrative proteomics and transcriptomics of human T-cells reveals temporal metabolic reprogramming following TCR-induced activation
Weerakoon, H.; Mohamed, A.; Wong, Y.; Senadheera, B.; Haigh, O.; S. Watkins, T.; Kazakoff, S.; Mukhopadhyay, P.; Mulvenna, J.; J Miles, J.; M. Hill, M.; Lepletier, A.
10.1101/2023.03.17.532022 — systems biology — Posted on 2023-03-20
1776 Ensemble and Iterative Engineering for Maximized Bioconversion to the Blue Pigment, Indigoidine from Non-Canonical Sustainable Carbon Sources
Eng, T. T.; Banerjee, D.; Menasalvas, J.; Chen, Y.; Gin, J.; Choudhary, H.; Baidoo, E.; Chen, J. H.; Ekman, A.; Kakumanu, R.; Diercks, Y. L.; Codik, A.; Larabell, C.; Gladden, J.; Simmons, B. A.; Keasling, J. D.; Petzold, C. J.; Mukhopadhyay, A.
10.1101/2023.03.16.532821 — systems biology — Posted on 2023-03-20
1781 Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy
Nitta, Y.; Osaka, J.; Maki, R.; Hakeda-Suzuki, S.; Suzuki, E.; Ueki, S.; Suzuki, T.; Sugie, A.
10.1101/2023.03.17.533056 — pathology — Posted on 2023-03-20
1782 Leptomeningeal anti-tumor immunity follows unique signaling principles
Remsik, J.; Tong, X.; Kunes, R. Z.; Li, M. J.; Osman, A.; Chabot, K.; Sener, U.; Wilcox, J. A.; Isakov, D.; Snyder, J.; Bale, T.; Chaligne, R.; Pe'er, D. D.; Boire, A.
10.1101/2023.03.17.533041 — cancer biology — Posted on 2023-03-20
1784 Mitigation of membrane morphology defects explain stability and orientational specificity of CLC dimers
Ozturk, T. N.; Bernhardt, N.; Schwartz, N.; Chadda, R.; Robertson, J. L.; Faraldo-Gomez, J.
10.1101/2023.03.16.533024 — biophysics — Posted on 2023-03-20
1793 Novel endogenous engineering platform for robust loading and delivery of functional mRNA by extracellular vesicles
Zickler, A. M.; Liang, X.; de Luca, M.; Gupta, D.; Corso, G.; Errichelli, L.; Hean, J.; Kamei, N.; Niu, Z.; Zhou, G.; Roudi, S.; Nordin, J.; Castilla-Llorente, V.; EL Andaloussi, S.
10.1101/2023.03.17.533081 — bioengineering — Posted on 2023-03-20
1794 A flexible implant for acute intrapancreatic electrophysiology
Pascual, D.; Brauns, L.; Domes, R.; Tisler, M. K.; Koegel, M.; Stumpf, A.; Kraushaar, U.; Jones, P. D.
10.1101/2023.03.17.532901 — bioengineering — Posted on 2023-03-20
1796 Genomic insights into greater yam tuber quality traits
Zotta Mota, A.; DOSSA, K.; Lechaudel, M.; CORNET, D.; MOURNET, P.; LOPEZ, D.; CHAIR, H.
10.1101/2023.03.17.532727 — genomics — Posted on 2023-03-20
1797 Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet
Hoffman, G. E.; Lee, D.; Bendl, J.; Fnu, P.; Hong, A.; Casey, C.; Alvia, M.; Shao, Z.; Argyriou, S.; Therrien, K.; Venkatesh, S.; Voloudakis, G.; Haroutunian, V.; Fullard, J. F.; Roussos, P.
10.1101/2023.03.17.533005 — genomics — Posted on 2023-03-20
1798 Pulmonary maternal immune activation does not extend through the placenta but leads to fetal metabolic adaptation
Schmidt Kjolner Hansen, S.; Krautz, R.; Rago, D.; Havelund, J.; Fargeman, N. J.; Prezelin, A.; Riviere, J.; Couturier-Tarrade, A.; Akimov, V.; Blagoev, B.; Elfving, B.; Stigliani, A.; Vogel, U.; Khodosevich, K.; Sorig-Hougaard, K.; Sandelin, A.
10.1101/2023.03.17.532052 — genomics — Posted on 2023-03-20
1799 Forest structural diversity determines tree growth synchrony in response to climate change
Astigarraga, J.; Calatayud, J.; Ruiz-Benito, P.; Madrigal-Gonzalez, J.; Tijerin-Trivino, J.; Zavala, M. A.; Andivia, E.; Herrero, A.
10.1101/2023.03.17.532989 — ecology — Posted on 2023-03-20
1800 Trends in mosquito species distribution modeling: insights for vector surveillance and disease control
Lippi, C. A.; Mundis, S. J.; Sippy, R.; Flenniken, M.; Chaudhary, A.; Hecht, G.; Carlson, C. J.; Ryan, S. J.
10.1101/2023.03.16.533046 — ecology — Posted on 2023-03-20
1802 Functional convergence underground? The scale-dependency of community assembly processes in European cave spiders
Mammola, S.; Graco-Roza, C.; Ballarin, F.; Hesselberg, T.; Isaia, M.; Lunghi, E.; Mouron, S.; Pavlek, M.; Tolve, M.; Cardoso, P.
10.1101/2023.03.17.533085 — ecology — Posted on 2023-03-20
1803 Relating polar bears killed, human presence, and ice conditions in Svalbard 1987-2019
Vongraven, D.; Amstrup, S. C.; McDonald, T. L.; Mitchell, J.; Yoccoz, N. G.
10.1101/2023.03.17.533082 — ecology — Posted on 2023-03-20
1804 Universal recording of cell-cell contacts in vivo for interaction-based transcriptomics
Nakandakari-Higa, S.; Canesso, M. C. C.; Walker, S.; Chudnovskiy, A.; Jacobsen, J. T.; Parigi, S. M.; Fiedorczuk, K.; Fuchs, E.; Bilate, A. M.; Pasqual, G.; Mucida, D.; Pritykin, Y.; Victora, G. D.
10.1101/2023.03.16.533003 — immunology — Posted on 2023-03-20
1806 Seed Longevity is Controlled by Metacaspases
Liu, C.; Hatzianestis, I. H.; Pfirrmann, T.; Reza, S. H.; Minina, A. A.; Moazzami, A.; Stael, S.; Gutierez-Beltran, E.; Pitsili, E.; Doermann, P.; D Andrea, S.; Gevaert, K.; Romero-Campero, F.; Ting, P.; Nowack, M. K.; Van Breusegem, F.; Jones, J. D.; Bozhkov, P. V.; Moschou, P. N.
10.1101/2023.03.19.533321 — plant biology — Posted on 2023-03-20
1807 Highly Parallel Tissue Grafting for Combinatorial In Vivo Screening
O'Connor, C. E.; Neufeld, A.; Fortin, C. L.; Johansson, F.; Mene, J.; Saxton, S. H.; Simmonds, S. P.; Kopyeva, I.; Gregario, N. E.; DeForest, C. A.; Witten, D. M.; Stevens, K. R.
10.1101/2023.03.16.533029 — bioengineering — Posted on 2023-03-20
1808 Characterization of popcorn temperate and tropical populations and GWAS for zeins and starch contents
Gotardi, L. F.; Viana, J. M. S.; Ribeiro, M. P.; Castro, R. B.; Ramos, H. J. d. O.; Fietto, J. L. R.
10.1101/2023.03.16.533023 — genetics — Posted on 2023-03-20
1809 Popcorn haploids identified by Navajo phenotype and ploidy level
Silva, J. P. A.; Viana, J. M. S.; Dias, K. O. G.; Silva, J. C.; Tupper, V. T. B.; Clarindo, W. R.
10.1101/2023.03.16.533026 — genetics — Posted on 2023-03-20
1811 The genetic and physiological basis of Arabidopsis thaliana tolerance to Pseudomonas viridiflava
Duque-Jaramillo, A.; Ulmer, N.; Alseekh, S.; Bezrukov, I.; Fernie, A. R.; Skirycz, A.; Karasov, T. L.; Weigel, D.
10.1101/2023.03.18.533268 — plant biology — Posted on 2023-03-20
1812 A Tyrosine Phospho-switch within the Longin Domain of VAMP721 modulates SNARE functionality
Ricardi, M. M.; Wallmeroth, N.; Cermesoni, C.; Mehlhorn, D. G.; Richter, S.; Zhang, L.; Mittendorf, J.; Godehardt, I.; Berendzen, K. W.; von Roepenack-Lahaye, E.; Stierhof, Y. D.; Lipka, V.; Juergens, G.; Grefen, C.
10.1101/2023.03.18.533296 — plant biology — Posted on 2023-03-20
1813 Cell type-specific control of secondary cell wall formation by Musashi-type translational regulators in Arabidopsis
Kairouani, A.; Pontier, D.; Picart, C.; Mounet, F.; Martinez, Y.; Le-Bot, L.; Fanuel, M.; Hammann, P.; Belmudes, L.; Merret, R.; Azevedo, J.; Carpentier, M.-C.; Gagliardi, D.; Coute, Y.; Sibout, R.; Bies-Etheve, N.; LAGRANGE, T.
10.1101/2023.03.20.532888 — plant biology — Posted on 2023-03-20
1815 The aerial epidermis is a major site of quinolizidine alkaloid biosynthesis in narrow-leafed lupin
Frick, K. M.; Lorensen, M. D. B. B.; Esteban, E.; Pasha, A.; Schulz, A.; Provart, N. J.; Janfelt, C.; Nour-Eldin, H. H.; Geu-Flores, F.
10.1101/2023.03.20.532575 — plant biology — Posted on 2023-03-20
1817 Analysis of spike protein variants evolved in a novel mouse model of persistent SARS-CoV-2 infection
Kim, D.; Kim, J.; Kim, M.; Park, H.; Maharjan, S.; Baek, K.; Kang, B. M.; Kim, S.; Park, S.; Park, M.-S.; Lee, Y.; Kwon, H.-J.
10.1101/2023.03.19.533317 — microbiology — Posted on 2023-03-20
1818 SARS-CoV-2 NSP12 associates with the TRiC complex and the P323L substitution is a host adaption.
Alruwaili, M.; Armstrong, S.; Prince, T.; Erdmann, M.; Davidson, A. D.; Matthews, D. A.; AlJabr, W.; Hiscox, J. A.
10.1101/2023.03.18.533280 — microbiology — Posted on 2023-03-20
1819 Coronavirus endoribonuclease nsp15 induces host cellular protein synthesis shutoff
Liao, Y.; Gong, X.; Feng, S.; Gao, B.; Fang, S.; Weng, W.; Chu, H.; Yuan, Y.; Cheng, Y.; Sun, Y.; Tan, L.; Song, C.; Qiu, X.; Ding, C.; Liao, M.; Tijhaar, E.; Forlenza, M.
10.1101/2023.03.20.533404 — microbiology — Posted on 2023-03-20
1821 Mouse Adapted SARS-CoV-2 Model Induces "Long-COVID" Neuropathology in BALB/c Mice
Gressett, T. E.; Leist, S. R.; Ismael, S.; Talkington, G.; Dinnon, K. H.; Baric, R. S.; Bix, G.
10.1101/2023.03.18.533204 — neuroscience — Posted on 2023-03-20
1822 Enhanced protective efficacy of a novel, thermostable, RBD-S2 fusion immunogen against SARS-CoV-2 and its variants
Mittal, N.; Kumar, S.; Rajmani, R. S.; Singh, R.; Lemoine, C.; Jakob, V.; BJ, S.; Bhat, M.; Chakraborty, D.; Pandey, S.; Jory, A.; S.A., S. S.; Kleanthous, H.; Dubois, P.; Ringe, R. P.; Varadarajan, R.
10.1101/2023.03.19.533338 — biophysics — Posted on 2023-03-20
1823 Zooanthroponotic transmission of SARS-CoV-2 and host-specific viral mutations revealed by genome-wide phylogenetic analysis
Naderi, S.; Chen, P. E.; Murall, C. L.; Poujol, R.; Kraemer, S. A.; Pickering, B. S.; Sagan, S. M.; Shapiro, B. J.
10.1101/2022.06.02.494559 — genomics — Posted on 2023-03-20
1824 Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells
Liu, S.; Yu, Y.; Ren, B.-G.; Yehezkel, T.; Obert, C.; Smith, M.; Wang, W.; Ostrowska, A.; Soto-Gutierrez, A.; Luo, J.
10.1101/2023.03.16.532991 — genomics — Posted on 2023-03-20
1825 Chemodiversity affects preference for Tanacetum vulgare chemotypes in two aphid species
Neuhaus-Harr, A.; Ojeda-Prieto, L.; Eilers, E.; Muller, C.; Weisser, W. W.; Heinen, R.
10.1101/2023.03.16.532937 — ecology — Posted on 2023-03-20
1826 Stability and heterogeneity in the anti-microbiota reactivity of human milk-derived Immunoglobulin A
Hand, T. W.; Johnson-Hence, C.; Gopalakrishna, K. P.; Bodkin, D.; Coffey, K. E.; Burr, A. H. P.; Rahman, S.; Rai, A. T.; Abbott, D. A.; Sosa, Y. A.; Tometich, J. T.; Das, J.
10.1101/2023.03.16.532940 — immunology — Posted on 2023-03-20
1827 Muscle of obese insulin-resistant humans exhibits losses in proteostasis and attenuated proteome dynamics that are improved by exercise training.
Srisawat, K.; Stead, C. A.; Hesketh, K.; Pogson, M.; Strauss, J. A.; Cocks, M.; Siekmann, I.; Phillips, S. M.; Lisboa, P. J.; Shepherd, S.; Burniston, J. G.
10.1101/2023.03.16.532839 — physiology — Posted on 2023-03-20
1830 ALaSCA: A novel in silico simulation platform to untangle biological pathway mechanisms, with a case study in Type 1 Diabetes progression
Louw, C.; Truter, N.; Bergh, W.; Van den Heever, M.; Horn, S.; Oudrhiri, R.; Van Niekerk, D. D.; Loos, B.; Singh, R.
10.1101/2023.03.16.532913 — bioinformatics — Posted on 2023-03-20
1832 How far are we from personalized gene expression prediction using sequence-to-expression deep neural networks?
Sasse, A.; Ng, B.; Spiro, A.; Tasaki, S.; Bennett, D.; Gaiteri, C.; De Jager, P. L.; Chikina, M.; Mostafavi, S.
10.1101/2023.03.16.532969 — bioinformatics — Posted on 2023-03-20
1836 REAL-TIME AT-LINE MONITORING OF INFLUENZA VIRUS IN CELL CULTURE BY A SURFACE PLASMON RESONANCE BIOSENSOR
Durous, L.; Padey, B.; Traversier, A.; Chupin, C.; Julien, T.; Marquette, C.; Rosa-Calatrava, M.; Petiot, E.
10.1101/2023.03.16.532923 — bioengineering — Posted on 2023-03-20
1838 Validation of marker-less pose estimation for 3D kinematics during upper limb reaching
Avni, I.; Landau, L.; Shaked, G.; Rabani, A. S.; Riemer, R.; Arac, A.; Shmuelof, L.
10.1101/2023.03.16.532711 — bioengineering — Posted on 2023-03-20
1843 Mating systems and recombination landscape strongly shape genetic diversity and selection in wheat relatives
Burgarella, C.; Bremaud, M.-F.; Von Hirschheydt, G.; Viader, V.; Ardisson, M.; Santoni, S.; Ranwez, V.; David, J.; Glemin, S.
10.1101/2023.03.16.532584 — evolutionary biology — Posted on 2023-03-20
1845 Adaptive evolution in virulence effectors of the rice blast fungus Pyricularia oryzae
Le Naour--Vernet, M.; Charriat, F.; Gracy, J.; Cros-Arteil, S.; Ravel, S.; Veillet, F.; Meusnier, I.; Padilla, A.; Kroj, T.; Cesari, S.; Gladieux, P.
10.1101/2023.03.16.532886 — evolutionary biology — Posted on 2023-03-20
1846 A syntelog-based pan-genome provides insights into rice domestication and de-domestication
Dongya, W.; Xie, L.; Sun, Y.; Huang, Y.; Jia, L.; Dong, C.; Shen, E.; Ye, C.-Y.; Qian, Q.; Fan, L.
10.1101/2023.03.17.533115 — evolutionary biology — Posted on 2023-03-20
1850 Fate-mapping lymphocyte clones and their progenies from induced antigen-signals identifies temporospatial behaviours of T cells mediating tolerance
Takahashi, M.; So, T.; Williamson, K.; Hosseini, Z.; Kania, K.; Ruhle, M.; Mann, T.; Schujis, M. J.; Coupland, P.; Naisbitt, D.; Halim, T. Y. F.; Lyons, P. A.; Lio, P.; Okkenhaug, K.; Adams, D. J.; Smith, K. G. C.; Jodrell, D. I.; Chapman, M. A.; Thaventhiran, J. E. D.
10.1101/2023.03.16.532070 — immunology — Posted on 2023-03-20
1853 Single-cell Electrochemical Aptasensor Array
Li, S.; Coffinier, Y.; Lagadec, C.; Cleri, F.; Nishiguchi, K.; Fujiwara, A.; Kim, S. H.; Clement, N.
10.1101/2023.03.16.532912 — bioengineering — Posted on 2023-03-20
1857 Genetic bases of resistance to the rice hoja blanca disease deciphered by a QTL approach
Silva, A.; Montoya, M. E.; Quintero, C.; Cuasquer, J.; Tohme, J.; Graterol, E.; Cruz, M.; Lorieux, M.
10.1101/2022.11.07.515427 — genetics — Posted on 2023-03-20
1858 Degenerated CRISPRs widely regulate Cas expression to balance immunity and cost
Liu, C.; Wang, R.; Li, J.; Cheng, F.; Shu, X.; Zhao, H.; Xue, Q.; Yu, H.; Wu, A.; Wang, L.; Hu, S.; Zhang, Y.; Yang, J.; Xiang, H.; Li, M.
10.1101/2023.03.10.532045 — microbiology — Posted on 2023-03-20
1859 Activity of Sotrovimab against BQ.1.1 and XBB.1 Omicron sublineages in a hamster model
Driouich, J.-S.; Bernadin, O.; Touret, F.; de Lamballerie, X.; Nougairede, A.
10.1101/2023.01.04.522629 — microbiology — Posted on 2023-03-20
1860 A hybrid and poly-polish workflow for the complete and accurate assembly of phage genomes: a case study of ten przondoviruses
Elek, C. K. A.; Brown, T. L.; Le Viet, T.; Evans, R.; Baker, D. J.; Telatin, A.; Tiwari, S. K.; Al-Khanaq, H.; Thilliez, G.; Kingsley, R. A.; Hall, L. J.; Webber, M. A.; Adriaenssens, E. M.
10.1101/2023.03.09.531871 — microbiology — Posted on 2023-03-20
1864 Part-night exposure to artificial light at night has more detrimental effects on aphid colonies than fully lit nights
Heinen, R.; Sanchez-Mahecha, O.; Bezemer, T. M.; Dominoni, D. M.; Knappe, C.; Kollmann, J.; Kopatsch, A.; Pfeiffer, Z. A.; Schloter, M.; Sturm, S.; Schnitzler, J. P.; Vlot, A. C.; Weisser, W. W.
10.1101/2022.10.24.513514 — ecology — Posted on 2023-03-20
1866 Cardiac contraction and relaxation are regulated by beta 1 adrenergic receptor generated cAMP pools at distinct membrane locations
Lin, T.-Y.; Mai, Q. N.; Zhang, H.; Wilson, E.; Chien, H.-C.; Yee, S. W.; Giacomini, K. M.; Olgin, J. E.; Irannejad, R.
10.1101/2022.07.13.499965 — cell biology — Posted on 2023-03-20
1867 Identification of levoglucosan degradation pathways in bacteria and sequence similarity network analysis
Kaur, A.; Scott, N. E.; Herisse, M.; Goddard-Borger, E. D.; Pidot, S. J.; Williams, S. J.
10.1101/2023.01.28.526070 — microbiology — Posted on 2023-03-20
1872 The response to drought-stressed host plants varies among herbivorous mite populations from a climate gradient
Migeon, A.; Auger, P.; Fossati-Gaschigard, O.; Hufbauer, R. A.; Miranda, M.; Zriki, G.; Navajas, M.
10.1101/2021.10.21.465244 — zoology — Posted on 2023-03-20
1873 GDF15 mediates renal cell plasticity in response to potassium depletion
Lasaad, S.; Walter, C.; Rafael, C.; Morla, L.; Doucet, A.; Picard, N.; Blanchard, A.; Fromes, Y.; Matot, B.; Crambert, G.; Cheval, L.
10.1101/2022.12.27.521983 — physiology — Posted on 2023-03-20
1874 Divergent roles for caspase-8 and MLKL in high-fat diet induced obesity and NAFLD in mice
Tye, H.; Conos, S. A.; Djajawi, T. M.; Abdoulkader, N.; Kong, I. Y.; Kaummon, H. L.; Narayana, V. K.; Speir, M.; Gottschalk, T. A.; Emery, J.; Simpson, D. S.; Hall, C.; Vince, A. J.; Russo, S.; Crawley, R.; Rashidi, M.; Hildebrand, J.; Murphy, J. M.; Whitehead, L.; De Souza, D. P.; Masters, S. L.; Hawkins, E. D.; Murphy, A. J.; Vince, J.; Lawlor, K.
10.1101/2023.03.14.532682 — immunology — Posted on 2023-03-20
1875 Genomic resources for a historical collection of cultivated two-row European spring barley genotypes.
Schreiber, M.; Wonneberger, R.; Haaning, A. M.; Coulter, M.; Russell, J.; Himmelbach, A.; Fiebig, A.; Muehlbauer, G. J.; Stein, N.; Waugh, R.
10.1101/2023.03.06.531259 — plant biology — Posted on 2023-03-20
1876 ATG5 suppresses type I IFN-dependent neutrophil swarming and NETosis
Kinsella, R. L.; Sur Chowdhury, C.; Smirnov, A.; Mreyoud, Y.; Kimmey, J. M.; Esaulova, E.; Kreamalmeyer, D.; Artyomov, M.; Stallings, C. L.
10.1101/2023.03.18.533244 — immunology — Posted on 2023-03-19
1877 Autophagy functions in lung macrophages and dendritic cells to suppress TH17 responses and neutrophil accumulation during allergic airway inflammation
Dubey, N.; Woodson, R.; McKee, S. R.; Rosen, A. L.; Rivera-Espinal, N.; Kreamalmeyer, D.; Kau, A. L.; Stallings, C. L.
10.1101/2023.03.16.533006 — immunology — Posted on 2023-03-19
1878 Neoepitope formation through the generation of RNA-derived "editopes"
Casati, B.; Pinamonti, V.; Pecori, R.; Lindner, J. M.; Papavasiliou, F. N.
10.1101/2023.03.16.532918 — cancer biology — Posted on 2023-03-19
1879 Mutational processes of tobacco smoking and APOBEC activity generate protein-truncating mutations in cancer genomes
Adler, N.; Bahcheli, A. T.; Cheng, K.; Al-Zahrani, K. N.; Slobodyanyuk, M.; Pellegrina, D.; Schramek, D.; Reimand, J.
10.1101/2023.03.19.533271 — cancer biology — Posted on 2023-03-19
1880 Identification of selective sweeps in bacteria
Avram, O.; Levy Karin, E.; Corander, J.; Oren, Y.; Pupko, T.
10.1101/2023.03.16.533065 — bioinformatics — Posted on 2023-03-19
1881 Thermodynamic and kinetic analysis of the LAO binding protein and its isolated domains reveal non-additivity in stability, folding, and function
Vergara, R.; Berrocal, T.; Juarez Mejia, E. I.; Romero-Romero, S.; Velaquez-Lopez, I.; Pulido, N.; Lopez Sanchez, H. A.; Silva, D.-A.; Costas, M.; Rodriguez-Romero, A.; Rodriguez-Sotres, R.; Sosa-Peinado, A.; Fernandez-Velasco, D. A.
10.1101/2023.03.18.532921 — biochemistry — Posted on 2023-03-19
1885 De novo mutation rates in sticklebacks
Zhang, C.; Reid, K.; Sands, A. F.; Fraimout, A.; Schierup, M. H.; Merila, J.
10.1101/2023.03.16.532904 — genomics — Posted on 2023-03-19
1886 Purkinje-Enriched snRNA-seq in SCA7 Cerebellum Reveals Zebrin Identity Loss as a Central Feature of Polyglutamine Ataxias
Bartelt, L. C.; Switonski, P. M.; Carvalho, J.; Duvick, L. A.; Scoles, D. R.; Pulst, S. M.; Orr, H. T.; Hull, C.; Lowe, C. B.; La Spada, A. R.
10.1101/2023.03.19.533345 — genomics — Posted on 2023-03-20
1888 Comparative landscape of genetic dependencies in human and chimpanzee stem cells
She, R.; Fair, T.; Schaefer, N. K.; Saunders, R. A.; Pavlovic, B. J.; Weissman, J. S.; Pollen, A. A.
10.1101/2023.03.19.533346 — evolutionary biology — Posted on 2023-03-20
1889 The first proof of concept demonstration of nanowarming in coral tissue
Daly, J.; Bouwmeester, J.; Perry, R.; Page, C.; Khosla, K.; Kangas, J.; Lager, C.; Hardy, K.; Bischof, J.; Hagedorn, M.
10.1101/2023.03.16.533048 — ecology — Posted on 2023-03-19
1891 Cationic Polymers Enable Internalization of Negatively Charged Chemical Probe into Bacteria
Lembke, H. K.; Espinasse, A.; Hanson, M. G.; Grimme, C. J.; Tan, Z.; Reineke, T. M.; Carlson, E. E.
10.1101/2023.03.19.533359 — microbiology — Posted on 2023-03-19
1892 The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in Staphylococcus aureus
Sharkey, L. K. R.; Guerillot, R.; Walsh, C. J.; Turner, A. M.; Lee, J. Y. H.; Neville, S. L.; Klatt, S.; Baines, S. L.; Pidot, S. J.; Rossello, F. J.; Seeman, T.; McWilliam, H.; Cho, E.; Carter, G. P.; Howden, B. P.; McDevitt, C. A.; Hachani, A.; Stinear, T. P.; Monk, I. R.
10.1101/2023.02.27.530350 — microbiology — Posted on 2023-03-20
1893 Pro-inflammatory feedback loops define immune responses to pathogenic lentivirus infection
Wilk, A. J.; Marceau, J. O.; Kazer, S. W.; Fleming, I.; Miao, V. N.; Galvez-Reyes, J.; Shalek, A. K.; Holmes, S.; Overbaugh, J.; Blish, C. A.
10.1101/2023.03.19.533358 — immunology — Posted on 2023-03-19
1896 Spatial omics representation and functional tissue module inference using graph Fourier transform
Chang, Y.; Liu, J.; Ma, A.; Jiang, S.; Krull, J.; Yeo, Y.; Liu, Y.; Rodig, S.; Barouch, D. H.; Fan, R.; Xu, D.; Li, Z.; Liu, B.; Ma, Q.
10.1101/2022.12.10.519929 — bioinformatics — Posted on 2023-03-19
1898 Molecular early burst associated with the diversification of birds at the K-Pg boundary
Berv, J. S.; Singhal, S.; Field, D. J.; Walker-Hale, N.; McHugh, S. W.; Shipley, J. R.; Miller, E. T.; Kimball, R. T.; Braun, E. L.; Dornburg, A.; Parins-Fukuchi, C. T.; Prum, R. O.; Winger, B. M.; Friedman, M.; Smith, S. A.
10.1101/2022.10.21.513146 — evolutionary biology — Posted on 2023-03-20
1900 Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice
Brown, A. J.; Won, J.; Wolfisberg, R.; Fanhoe, U.; Catanzaro, N.; West, A.; Moreira, F.; Nogeuira Batista, M.; Ferris, M. T.; Linnertz, C.; Leist, S. R.; Nguyen, C.; De la Cruz, G.; Midkiff, B.; Xia, Y.; Montgomery, S. A.; Billerbeck, E.; Bukh, J.; Scheel, T.; Rice, C. M.; Sheahan, T. P.
10.1101/2023.03.18.533278 — microbiology — Posted on 2023-03-19
1902 Endogenous Staphylococcus aureus CRISPR-cas system limits phage proliferation and efficiently excises from the genome as part of the SCCmec cassette
Mikkelsen, K.; Bowring, J. Z.; Ng, Y. K.; Frisinger, F. S.; Maglegaard, J. K.; Li, Q.; Sieber, R. N.; Petersen, A.; Andersen, P. S.; Rostoel, J. T.; Hoeyland-Kroghsbo, N. M.; Ingmer, H.
10.1101/2023.03.19.533347 — microbiology — Posted on 2023-03-19
1904 Peripheral detection of viruses shapes brain immunity and behavior in zebrafish
Kraus, A.; Garcia, B.; Ma, J.; Herrera, K. J.; Zwaka, H.; Karpaz, R.; Wong, R.; Engert, F.; Salinas, I.
10.1101/2023.03.17.533129 — immunology — Posted on 2023-03-19
1905 Astrocytes control cocaine-induced synaptic plasticity and reward through the matricellular protein hevin
Mongredien, R.; Anesio, A.; Fernandes, G. J. D.; Eagle, A. L.; Maldera, S.; Pham, C.; Vilette, A.; Bianchi, P. C.; Franco, C.; Louis, F.; Gruszczynski, C.; Betancur, C.; Erdozain, A. M.; Robison, A. J.; Boucard, A. A.; Li, D. J.; Cruz, F. C.; Gautron, S.; Heck, N.; Vialou, V.
10.1101/2023.03.19.533284 — neuroscience — Posted on 2023-03-19
1906 Single session of rTMS enhances brain metastability and intrinsic ignition
Bhardwaj, S.; Panda, R.; Bharath, R. D.; Stezin, A.; Khokhar, S. K.; Prasad, S.; Tyagi, V.; Kamble, N.; Kumar, K.; M, N.; Yadav, R.; Kashyap, R.; Udupa, K.; Annen, J.; Laureys, S.; Deco, G.; Pal, P. K.
10.1101/2022.08.14.503887 — neuroscience — Posted on 2023-03-19
1907 Normative Modeling of Brain Morphometry Across the Lifespan using CentileBrain: Algorithm Benchmarking and Model Optimization
Ge, R.; Yu, Y.; Qi, Y. X.; Fan, Y. V.; Chen, S.; Gao, C.; Haas, S. S.; Modabbernia, A.; New, F.; Agartz, I.; Asherson, P.; Ayesa-Arriola, R.; Banaj, N.; Banaschewski, T.; Baumeister, S.; Bertolino, A.; Boomsma, D. I.; Borgwardt, S.; Bourque, J.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R. M.; Buckner, R.; Buitelaar, J. K.; Cannon, D. M.; Caseras, X.; Cervenka, S.; Conrod, P. J.; Crespo-Facorro, B.; Crivello, F.; Crone, E. A.; de Haan, L.; de Zubicaray, G. I.; Di Giorgio, A.; Erk, S.; Fisher, S. E.; Franke, B.; Frodl, T.; Glahn, D. C.; Grotegerd, D.; Gruber, O.; Gruner, P.; Gur, R. E.; G
10.1101/2023.01.30.523509 — bioinformatics — Posted on 2023-03-19
1908 A double-hit of social and economic stress in mice precipitates changes in decision-making strategies
Durand-de Cuttoli, R.; Martinez-Rivera, F. J.; Li, L.; Minier-Toribio, A.; Dong, Z.; Cai, D. J.; Russo, S. J.; Nestler, E. J.; Sweis, B. M.
10.1101/2023.03.19.533304 — animal behavior and cognition — Posted on 2023-03-19
1910 Non-catalytic regulation of 18S rRNA methyltransferase DIMT1 in acute myeloid leukemia
Gonskikh, Y.; Stoute, J.; Shen, H.; Pingul, B.; Budinich, K.; Schultz, K.; Elashal, H.; Marmorstein, R. F.; Shi, J.; Liu, K. F.
10.1101/2023.03.18.533235 — molecular biology — Posted on 2023-03-19
1911 Schwann cells modulate nociception in neurofibromatosis 1
Raut, N. G.; Maile, L. A.; Oswalt, L. M.; Mitxelena, I.; Adlakha, A.; Sprague, K. L.; Rupert, A. R.; Bokros, L.; Hofmann, M. C.; Patritti-Cram, J.; Rizvi, T. A.; Queme, L. F.; Choi, K.; Ratner, N.; Jankowski, M. P.
10.1101/2023.03.18.533004 — neuroscience — Posted on 2023-03-19
1912 Dopamine neurons govern olfactory-gated infant begging behavior
Butler, J. M.; Singh, D.; Baker, P.; Edwards, S. V.; Summers, K.; O'Connell, L. A.
10.1101/2023.03.18.533277 — neuroscience — Posted on 2023-03-19
1915 Dual impact of PTEN mutation on CSF dynamics and cortical networks via the dysregulation of neural precursors and their interneuron descendants
DeSpenza, T.; Kiziltug, E.; Allington, G.; Barson, D.; O'Connor, D.; Robert, S. M.; Mekbib, K. Y.; Nanda, P.; Greenberg, A.; Singh, A.; Duy, P. Q.; Mandino, F.; Zhao, S.; Lynn, A.; Reeves, B. C.; Marlier, A.; Getz, S. A.; Nelson-Williams, C.; Shimelis, H.; Zhang, J.; Walsh, L. K.; Wang, W.; Smith, H.; OuYang, A.; Deniz, E.; Lake, E.; Jin, S. C.; Luikart, B. W.; Kahle, K. T.
10.1101/2023.03.18.533275 — neuroscience — Posted on 2023-03-19
1916 Effects of phase encoding direction on test-retest reliability of human functional connectome
Cao, H.; Barber, A.; Rubio, J. M.; Argyelan, M.; Gallego, J.; Lencz, T.; Malhotra, A.
10.1101/2023.03.18.533301 — neuroscience — Posted on 2023-03-19
1918 Breaking the C. elegans invasion/proliferation dichotomy
Martinez, M. A. Q.; Zhao, C.; Moore, F. E. Q.; Yee, C. S.; Zhang, W.; Shen, K.; Martin, B. L.; Matus, D. Q.
10.1101/2023.03.16.533034 — developmental biology — Posted on 2023-03-19
1919 Toxoplasma Membrane Inositol Phospholipid Binding Protein TgREMIND Is Essential for Secretory Organelle Function and Host Infection
Houngue, R.; Sangare, L. O.; Alayi, T. D.; Dieng, A.; Bitard-Feildel, T.; Boulogne, C.; Slomianny, C.; Atindehou, C. M.; Fanou, L. A.; Hathout, Y.; Saeij, J. P.; Callebaut, I.; Tomavo, S.
10.1101/2023.03.19.533351 — cell biology — Posted on 2023-03-19
1921 Defective callosal termination underlies the long-term behavioral deficits in NMDA receptor antibody encephalitis mouse model
Zhou, J.; Greenfield, A.; Loudermilk, R.; Bartley, C.; Tran, B.; Zhao, C.; Wang, H.; Wilson, M.; Pleasure, S.
10.1101/2022.09.29.510196 — neuroscience — Posted on 2023-03-19
1924 Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Abini-Agbomson, S.; Gretarsson, K.; Shih, R. M.; Hsieh, L.; Lou, T.; De Ioannes, P.; Vasilyev, N.; Lee, R.; Wang, M.; Simon, M.; Armache, J.-P.; Nudler, E.; Narlikar, G.; Liu, S.; Lu, C.; Armache, K.-J.
10.1101/2023.03.17.533220 — biochemistry — Posted on 2023-03-19
1926 Impaired BCAA catabolism during adipocyte differentiation decreases glycolytic flux
Green, C. R.; Wessendorf-Rodriguez, K. A.; Turner, R.; Hover, J. D.; Murphy, A. N.; Metallo, C. M.; Wallace, M.
10.1101/2022.05.27.493780 — cell biology — Posted on 2023-03-19
1927 SIRT-1 is required for release of enveloped picornaviruses
Jassey, A.; Logue, J.; Weston, S.; Wagner, M. A.; Galitska, G.; Miller, K. A.; Frieman, M. B.; Jackson, W. T.
10.1101/2022.08.12.503821 — microbiology — Posted on 2023-03-19
1929 Diverse and Abundant Viruses Exploit Conjugative Plasmids
Quinones-Olvera, N.; Owen, S. V.; McCully, L. M.; Marin, M. G.; Rand, E. A.; Fan, A. C.; Dosumu, O. J. M.; Paul, K.; Castano, C. E. S.; Paull, J. S.; Petherbridge, R.; Baym, M.
10.1101/2023.03.19.532758 — microbiology — Posted on 2023-03-19
1931 ZIP4 is required for normal progression of synapsis and for over 95% of crossovers in wheat meiosis.
Draeger, T. N.; Rey, M.-D.; Hayta, S.; Smedley, M.; Alabdullah, A.-K.; Moore, G.; Martin, A. C.
10.1101/2023.03.17.532993 — cell biology — Posted on 2023-03-19
1932 Curved adhesions mediate cell attachment to soft matrix fibres in 3D
Zhang, W.; Lu, C.-H.; Nakamoto, M. L.; Tsai, C.-T.; Roy, A. R.; Lee, C. E.; Yang, Y.; Jahed, Z.; Li, X.; Cui, B.
10.1101/2023.03.16.532975 — cell biology — Posted on 2023-03-19
1933 Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Gelot, C.; Kovacs, M. T.; Miron, S.; Mylne, E.; Ghouil, R.; Popova, T.; Dingli, F.; Loew, D.; Guirouilh-Barbat, J.; Del Nery, E.; Zinn-Justin, S.; Ceccaldi, R.
10.1101/2023.03.17.533134 — cell biology — Posted on 2023-03-19
1934 Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy
Perez-Ramirez, C. A.; Nakano, H.; Law, R. C.; Matulionis, N.; Thompson, J.; Pfeiffer, A.; Park, J. O.; Nakano, A.; Christofk, H. R.
10.1101/2023.03.16.532852 — cell biology — Posted on 2023-03-19
1935 Novel in-silico predicted matrikines are differential mediators of in vitro and in vivo cellular metabolism
Jariwala, N.; Ozols, M.; Eckersley, A.; Mambwe, B.; Watson, R. E. B.; Zeef, L.; Gilmore, A.; Debelle, L.; Bell, M.; Bradley, E. J.; Doush, Y.; Courage, C.; Leroux, R.; Peschard, O.; Mondon, P.; Ringenbach, C.; Bernard, L.; Pitois, A.; Sherratt, M. J.
10.1101/2023.03.17.533127 — cell biology — Posted on 2023-03-19
1938 Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy
Tao, X.; Liu, J.; Diaz-Perez, Z.; Foley, J. R.; Stewart, T. M.; Casero, R. A.; Zhai, G.
10.1101/2023.03.17.533015 — neuroscience — Posted on 2023-03-19
1940 Domino-like Effect of C112R Mutation on APOE4 Aggregation and Its Reduction by Alzheimer's Disease Drug Candidate
Nemergut, M.; Marques, S. M.; Uhrik, L.; Vanova, T.; Nezvedova, M.; Gadara, D. C.; Jha, D.; Tulis, J.; Novakova, V.; Planas-Iglesias, J.; Kunka, A.; Legrand, A.; Hribkova, H.; Pospisilova, V.; Sedmik, J.; Raska, J.; Prokop, Z.; Damborsky, J.; Bohaciakova, D.; Spacil, Z.; Hernychova, L.; Bednar, D.; Marek, M.
10.1101/2022.10.09.511473 — neuroscience — Posted on 2023-03-19
1942 The prophylactic value of TNF-α inhibitors against retinal ganglion cell apoptosis and optic nerve axon loss after corneal surgery or trauma
Paschalis, E. I.; Zhou, C.; Sharma, J.; Dohlman, T. H.; Kim, S.; Lei, F.; Chodosh, J.; Vavvas, D.; Urtti, A.; Papaliodis, G.; Dohlman, C. H.
10.1101/2022.10.06.510713 — pathology — Posted on 2023-03-19
1944 Hypoxic tumors are sensitive to FLASH radiotherapy
Leavitt, R. J.; Almeida, A.; Grilj, V.; Montay-Gruel, P.; Godfroid, C.; Petit, B.; Bailat, C.; Limoli, C. L.; Vozenin, M.-C.
10.1101/2022.11.27.518083 — cancer biology — Posted on 2023-03-19
1947 3D Imaging Reveals Resilience: Storm Impact on Coral Reef Structural Complexity
Yuval, M.; Pearl, N.; Tchernov, D.; Martinez, S.; Loya, Y.; Bar-Massada, A.; Treibitz, T.
10.1101/2022.12.04.519015 — ecology — Posted on 2023-03-19
1948 A human embryonic limb cell atlas resolved in space and time
Zhang, B.; He, P.; Lawrence, J. E.; Wang, S.; Tuck, E.; Williams, B. A.; Roberts, K.; Kleshchevnikov, V.; Mamanova, L.; Bolt, L.; Polanski, K.; Elmentaite, R.; Fasouli, E. S.; Prete, M.; He, X.; Yayon, N.; Fu, Y.; Yang, H.; Liang, C.; Zhang, H.; Blain, R.; Chedotal, A.; Fitzpatrick, D.; Firth, H.; Dean, A.; Marioni, J. C.; Barker, R. A.; Storer, M. A.; Wold, B.; Zhang, H.; Teichmann, S.
10.1101/2022.04.27.489800 — developmental biology — Posted on 2023-03-19
1949 Tobramycin adaptation alters the antibiotic susceptibility of Pseudomonas aeruginosa quorum sensing-null mutants
Abisado-Duquea, R. G.; McKee, B. M.; Townsend, K. A.; Woods, K.; Koirala, P.; Holder, A. J.; Craddock, V. D.; Cabeen, M. T.; Chandler, J. R.
10.1101/2023.01.13.523864 — microbiology — Posted on 2023-03-19
1950 Litter Matters: The Importance of Decomposition Products for Soil Bacterial Diversity and abundance of key groups of the N cycle in Tropical Areas
Diniz, P. P.; Borges, B. M. F.; Oliveira, A. P. d.; Coelho, M. R.; Aragao, O. O. d. S.; Ribeiro, T. G.; Rocha, F. I.; Alves, B. J. R.; Coelho, M. R. R.; Dias, E. S.; Cole, J. R. R.; Howe, A. C.; Mui, T. S.; Jesus, E. d. C.
10.1101/2023.03.03.530969 — microbiology — Posted on 2023-03-19
1952 A model-free approach to link neural activity to behavioral tasks
Costabile, J. D.; Balakrishnan, K. A.; Schwinn, S.; Haesemeyer, M.
10.1101/2022.08.31.506108 — neuroscience — Posted on 2023-03-19
1953 PXC2, a polarized receptor kinase, functions to repress ground tissue cell divisions and restrict stele size
Goff, J.; Rony, R. M. I. K.; Ge, Z.; Hajny, J.; Rodriguez-Furlan, C.; Friml, J.; Van Norman, J. M.
10.1101/2021.02.11.429611 — plant biology — Posted on 2023-03-19
1955 Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma
Ito, I.; Dickson, P. N.; Yousef, A. M.; Naini, Z. A.; White, M. G.; Fleten, K. G.; Flatmark, K.; Fournier, K. F.; Fowlkes, N. W.; Shen, J. P.
10.1101/2023.02.01.526672 — cancer biology — Posted on 2023-03-19
1962 Non-histone protein methylation in Trypanosoma cruzi epimastigotes
de Almeida, R. F.; Lucena, A. C. R.; Batista, M.; Marchini, F. K.; de Godoy, L. M. F.
10.1101/2022.03.12.484072 — genomics — Posted on 2023-03-19
1963 Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.
Yamashita, A.; Ignatenko, O.; Nguyen, M.; Lambert, R.; Watt, K.; Daneault, C.; Robillard-Frayne, I.; Topisirovic, I.; Des Rosiers, C.; McBride, H. M.
10.1101/2023.03.15.532715 — cell biology — Posted on 2023-03-19
1964 Medium depth influences O2 availability and metabolism in cultured RPE cells
Hass, D. T.; Zhang, Q.; Autterson, G.; Bryan, R.; Hurley, J. B.; Miller, J. M.
10.1101/2023.03.01.530623 — cell biology — Posted on 2023-03-19
1965 Odor-evoked transcriptomics of Aedes aegypti mosquitoes
Mappin, F.; Bellantuono, A. J.; Ebrahimi, B.; DeGennaro, M.
10.1101/2023.03.12.532230 — neuroscience — Posted on 2023-03-19
1969 Long-term precision editing of neural circuits in mammals using engineered gap junction hemichannels
Ransey, E.; Chesnov, K.; Thomas, G.; Wisdom, E.; Almoril-Porras, A.; Bowman, R.; Rodriguez, T.; Adamson, E.; Walder-Christensen, K. K.; Hughes, D. N.; Schwennesen, H.; Mague, S. D.; Colon-Ramos, D.; Hultman, R.; Bursac, N.; Dzirasa, K.
10.1101/2021.08.24.457429 — neuroscience — Posted on 2023-03-19
1971 Inhibitory and in silico molecular docking of Xeroderris stuhlmannii (Taub.) Mendonca & E.P. Sousa phytochemical compounds on human α-glucosidases
Nyathi, B.; Bvunzawabaya, J. T.; Mudawarima, C. V. P.; Manzombe, E.; Selemani, M. A.; Tsotsoro, K.; Munyuki, G.; Rwere, F.
10.1101/2022.09.16.508336 — plant biology — Posted on 2023-03-19
1972 Resolution Enhancement with a Task-Assisted GAN to Guide Optical Nanoscopy Image Analysis and Acquisition
Bouchard, C.; Wiesner, T.; Deschenes, A.; Bilodeau, A.; Turcotte, B.; Gagne, C.; Lavoie-Cardinal, F.
10.1101/2021.07.19.452964 — bioinformatics — Posted on 2023-03-19
1973 What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds
Durairaj, J.; Waterhouse, A. M.; Mets, T.; Brodiazhenko, T.; Abdullah, M.; Studer, G.; Akdel, M.; Andreeva, A.; Bateman, A.; Tenson, T.; Hauryliuk, V.; Schwede, T.; Pereira, J.
10.1101/2023.03.14.532539 — bioinformatics — Posted on 2023-03-19
1975 Antibodies generated in vitro and in vivo elucidate design of a thermostable ADDomer COVID-19 nasal nanoparticle vaccine
Buzas, D.; Bunzel, H. A.; Staufer, O.; Milodowski, E.; Edmonds, G.; Bufton, J.; Vidana Matteo, B.; Yadav, S.; Gupta, K.; Fletcher, C.; Kavanagh Williamson, M.; Harrison, A.; Borucu, U.; Capin, J.; Francis, O.; Balchin, G.; Hall, S.; Vivoli Vega, M.; Durbesson, F.; Vincentelli, R.; Roe, J.; Wooldridge, L.; Burt, R.; Anderson, R.; Mulholland, A. J.; Hare, J.; Bailey, M.; Davidson, A.; Finn, A.; Morgan, D.; Mann, J.; Spatz, J.; Garzoni, F.; Schaffitzel, C.; Berger, I.
10.1101/2023.03.17.533092 — biochemistry — Posted on 2023-03-19
1976 Development of novel cytoprotective small compounds inhibiting mitochondria-dependent apoptosis
Matsuyama, S.; Matsuyama, M.; Ortega, J.; Fedorov, Y.; Scott-McKean, J.; Muller-Greven, J.; Buck, M.; Adams, D.; Jastrzebska, B.; Greenlee, W.
10.1101/2022.10.12.511987 — cell biology — Posted on 2023-03-19
1980 Cryo-EM structure of the human Sirtuin 6-nucleosome complex
Chio, U. S.; Rechiche, O.; Bryll, A. R.; Zhu, J.; Feldman, J.; Peterson, C.; Tan, S.; Armache, J.-P.
10.1101/2023.03.17.533206 — biochemistry — Posted on 2023-03-18
1981 Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases
Lampe, G. D.; King, R. T.; Halpin-Healy, T. S.; Klompe, S. E.; Hogan, M. I.; Vo, P. L. H.; Tang, S.; Chavez, A.; Sternberg, S. H.
10.1101/2023.03.17.533036 — genetics — Posted on 2023-03-18
1984 Time-resolved molecular measurements reveal changes in astronauts during spaceflight
Zheng, M.; Charvat, J.; Zwart, S. R.; Mehta, S.; Crucian, B. E.; Smith, S. M.; He, J.; Piermarocchi, C.; Mias, G. I.
10.1101/2023.03.17.530234 — molecular biology — Posted on 2023-03-18
1988 Development of a Plasmodium vivax biobank for functional ex vivo assays
Dash, R.; Skillman, K.; Pereira, L.; Mascarenhas, A.; Dass, S.; Walke, J.; Almeida, A.; Fernandes, M.; Gomes, E.; White, J.; Chery-Karschney, L.; Khandeparkar, A.; Rathod, P. K.; Duraisingh, M. T.; Kanjee, U.
10.1101/2023.03.17.533128 — microbiology — Posted on 2023-03-18
1990 Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch
Handler, A.; Zhang, Q.; Pang, S.; Nguyen, T. M.; Iskols, M.; Nolan-Tamariz, M.; Cattel, S.; Plumb, R.; Sanchez, B.; Ashjian, K.; Shotland, A.; Brown, B.; Kabeer, M.; Turecek, J.; Rankin, G.; Xiang, W.; Pavarino, E. C.; Africawala, N.; Santiago, C.; Lee, W.-C. A.; Xu, C. S.; Ginty, D. D.
10.1101/2023.03.17.533188 — neuroscience — Posted on 2023-03-18
1991 Variational Log-Gaussian Point-Process Methods for Grid Cells
Rule, M. E.; Vayalambrone, P. C.; Krstulovic, M.; Bauza, M.; Krupic, J.; O'Leary, T.
10.1101/2023.03.18.533177 — neuroscience — Posted on 2023-03-18
1994 Single-Soma Deep RNA sequencing of Human DRG Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation
Yu, H.; Usoskin, D.; Nagi, S. S.; Hu, Y.; Kupari, J.; Bouchatta, O.; Cranfill, S. L.; Su, Y.; Lv, Y.; Song, H.; Ming, G.-L.; Prouty, S.; Seykora, J.; Wu, H.; Ma, M.; Olausson, H.; Ernfors, P.; Luo, W.
10.1101/2023.03.17.533207 — neuroscience — Posted on 2023-03-18
1998 Coupling of Slack and NaV1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development
Yuan, T.; Wang, Y.; Jin, Y.; Xu, S.; Zhang, H.; Chen, Q.; Li, N.; Ma, X.; Song, H.; Peng, C.; Yang, H.; Geng, Z.; Dong, J.; Duan, G.; Sun, Q.; Yang, Y.; Yang, F.; Huang, Z.
10.1101/2023.03.16.532982 — neuroscience — Posted on 2023-03-18
2003 DNA storage in thermoresponsive microcapsules for repeated random multiplexed data access
Bögels, B. W. A.; Nguyen, B. H.; Ward, D.; Gascoigne, L.; Schrijver, D. P.; Makri Pistikou, A.-M.; Joesaar, A.; Yang, S.; Voets, I. K.; Mulder, W. J. M.; Phillips, A.; Mann, S.; Seelig, G.; Strauss, K.; Chen, Y.-J.; de Greef, T.
10.1101/2023.03.17.533163 — synthetic biology — Posted on 2023-03-18
2004 Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
Abini-Agbomson, S.; Gretarsson, K.; Shih, R. M.; Hsieh, L.; Lou, T.; De Ioannes, P.; Vasilyev, N.; Lee, R.; Wang, M.; Simon, M.; Armache, J.-P.; Nudler, E.; Narlikar, G.; Liu, S.; Lu, C.; Armache, K.-J.
10.1101/2023.03.17.533220 — biochemistry — Posted on 2023-03-18
2006 A biophysical framework for double-drugging kinases
Kim, C.; Ludewig, H.; Hadzipasic, A.; Kutter, S.; Nguyen, V.; Kern, D.
10.1101/2023.03.17.533217 — biochemistry — Posted on 2023-03-18
2007 CRISPR-ChIP delineates a Menin-dependent oncogenic DOT1L complex in MLL-leukaemia
Gilan, O.; Bell, C.; Talarmain, L.; Neville, D.; Knezevic, K.; Ferguson, D.; Boudes, M.; Chan, Y.-c.; Davidovich, C.; Lam, E.; Dawson, M. A.
10.1101/2023.03.17.533231 — molecular biology — Posted on 2023-03-18
2008 The streptococcal phase-variable Type I Restriction-Modification system SsuCC20p dictates the methylome of Streptococcus suis and impacts virulence
Roodsant, T.; van der Putten, B. C.; Brizuela, J.; Coolen, J. P. M.; Baltussen, T. J. H.; Schipper, K.; Pannekoek, Y.; van der Ark, K. C. H.; Schultsz, C.
10.1101/2023.03.17.533248 — microbiology — Posted on 2023-03-18
2009 Attenuated Mycobacterium tuberculosis Vaccine Protection in a Low Dose Murine Challenge Model
Vidal, S. J.; Sellers, D.; Yu, J.; Wakabayashi, S.; Sixsmith, J.; Aid, M.; Barrett, J.; Stevens, S. F.; Liu, X.; Li, W.; Plumlee, C. R.; Urdahl, K. B.; Martinot, A. J.; Barouch, D. H.
10.1101/2023.03.17.533226 — microbiology — Posted on 2023-03-18
2011 Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer
Wortmann, E.; Osswald, A.; Wylensek, D.; Liang, W.; Treichel, N.; Schumacher, F.; Volet, C.; Matysik, S.; Kleigrewe, K.; Gigl, M.; Rohn, S.; Kleuser, B.; Liebisch, G.; Bernier-Latmani, R.; Schnieke, A.; Flisikowski, K.; Ocvirk, S.; Clavel, T.
10.1101/2023.03.17.533140 — microbiology — Posted on 2023-03-18
2013 Genome sequence and annotation of Periconia digitata, a promising biocontrol agent of phytopathogenic oomycetes
Bovio, E.; Rancurel, C.; Seassau, A.; Magliano, M.; Gislard, M.; Loisier, A.; Kuchly, C.; Ponchet, M.; Danchin, E. G.; Van Ghelder, C.
10.1101/2023.03.17.533154 — microbiology — Posted on 2023-03-18
2015 T6SS-mediated competitive exclusion among Pantoea agglomerans associated with plants
Ripcke, K.; Romero Picazo, D.; Vichare, S.; Unterweger, D.; Dagan, T.; Huelter, N. F.
10.1101/2023.03.17.533219 — microbiology — Posted on 2023-03-18
2016 Metabolic interplay between Proteus mirabilis and Enterococcus faecalis facilitates polymicrobial biofilm formation and invasive disease
Hunt, B. C.; Brix, V.; Vath, J.; Guterman, L. B.; Taddei, S. M.; Learman, B. S.; Brauer, A. L.; Armbruster, C. E.
10.1101/2023.03.17.533237 — microbiology — Posted on 2023-03-18
2017 Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery
Hindi, S.; Petrany, M.; Greenfeld, E.; Focke, L.; Cramer, A.; Whitt, M.; Prasad, V.; Chamberlain, J.; Podbilewicz, B.; Millay, D.
10.1101/2023.03.17.533157 — cell biology — Posted on 2023-03-18
2019 The mitophagy receptor Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
Field, J. T.; Chapman, D.; Ghavami, S.; West, A. R.; Saleem, A.; Kindrachuk, J.; Triggs-Raine, B.; Gordon, J. W.
10.1101/2023.03.18.532760 — cell biology — Posted on 2023-03-18
2021 Autophagy is Regulated by Mitochondrial Calcium Transporters NCLX and MCU
De Miranda Ramos, V.; Serna, J. D.; Vilas-Boas, E. A.; Cabral-Costa, J. V.; da Cunha, F. M.; Kowaltowski, A. J.
10.1101/2023.03.17.533187 — cell biology — Posted on 2023-03-18
2024 Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity
Patir, A.; Barrington, J.; Szymkowiak, S.; Straus, D.; Alfieri, A.; Lefevre, L.; Henderson, N. C.; Horsburgh, K.; Ramachandran, P.; McColl, B. W.
10.1101/2023.03.17.532588 — neuroscience — Posted on 2023-03-18
2025 Perirhinal Cortex Learns A Predictive Map of The Task Environment
Lee, D. G.; McLachlan, C. A.; Nogueira, R.; Kwon, O.; Carey, A.; House, G.; Lagani, G. D.; LaMay, D.; Fusi, S.; Chen, J. L.
10.1101/2023.03.17.532214 — neuroscience — Posted on 2023-03-18
2026 Statistical analyses of motion-corrupted MRI relaxometry data
Corbin, N.; Oliveira, R.; Raynaud, Q.; Di Domenicantonio, G.; Draganski, B.; Kherif, F.; Callaghan, M. F.; Lutti, A.
10.1101/2023.03.16.532911 — neuroscience — Posted on 2023-03-18
2030 Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing
Zhang, A.; Jin, L.; Yao, S.; Matsuyama, M.; Velthoven, C. v.; Sullivan, H.; Sun, N.; Kellis, M.; Tasic, B.; Wickersham, I. R.; Chen, X.
10.1101/2023.03.16.532873 — neuroscience — Posted on 2023-03-18
2033 A Weakly Supervised U-Net Model for Precise Whole Brain Immunolabeled Cell Detection
Wang, L.-W.; Wu, Y.-L.; Lee, C.-L.; Cheng, C.-C.; Lu, K.-Y.; Tsai, J.-H.; Lin, Y.-H.; Hsu, C.-H.; Kuo, T.-H.; Chu, L.-A.
10.1101/2023.03.16.531434 — neuroscience — Posted on 2023-03-18
2035 FLT3 signaling inhibition preserves opioid analgesia while abrogating tolerance and hyperalgesia
Jouvenel, A.; Tassou, A.; Thouaye, M.; Ruel, J.; Antri, M.; Leyris, J.-P.; Paquet, A.; Mallie, S.; Sar, C.; Diouloufet, L.; Sonrier, C.; Daubeuf, F.; Bertin, J.; Alves, S.; Venteo, S.; Frossard, N.; Carroll, P.; Mechaly, I.; Rognan, D.; Sokoloff, P.; Dallel, R.; Delmas, P.; Valmier, J.; Rivat, C.
10.1101/2023.03.16.532971 — neuroscience — Posted on 2023-03-18
2037 A Genetic Locus Mediating Attentional Processing
Gershon, Z. Z.; Bonito-Oliva, A.; Kanke, M.; Terceros, A.; Fak, J. J.; Gebrehemedin, M.; De Marco Garcia, N.; Iannone, A. F.; Sethupathy, P.; Rajasethupathy, P.
10.1101/2023.03.17.533136 — neuroscience — Posted on 2023-03-18
2041 Structured connectivity in the output of the cerebellar cortex
Gruver, K. M.; Y, J. W.; Fields, E.; Song, S.; Sjostrom, P. J.; Watt, A. J.
10.1101/2023.03.17.533173 — neuroscience — Posted on 2023-03-18
2042 Xiphoid nucleus of the midline thalamus controls cold-induced food seeking
Lal, N. K.; Le, P.; Aggarwal, S.; Zhang, A.; Wang, K.; Qi, T.; Pang, Z.; Yang, D.; Nudell, V.; Yeo, G. W.; Banks, A. S.; Ye, L.
10.1101/2023.03.16.533067 — neuroscience — Posted on 2023-03-18
2051 Ozone mediates tumor-selective cell death caused by air plasma-activated medium independently of NOx
Suzuki-Karasaki, Y.; Suzuki-Karasaki, M.; Ochiai, Y.; Innami, S.; Okajima, H.; Suzuki-Karasaki, M.; Nakayama, H.
10.1101/2023.03.17.533239 — cancer biology — Posted on 2023-03-18
2052 The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in HCT116 colon cancer cells
Slaninova, V.; Heron-Milhavet, L.; Robin, M.; Jeanson, L.; Kantar, D.; Tosi, D.; Berhelin, L.; Gongora, C.; Djiane, A.
10.1101/2023.03.17.533075 — cancer biology — Posted on 2023-03-18
2053 Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
Sun, Y.; Young, M. C.; Woodward, C. H.; Danon, J. N.; Truong, H. V.; Gupta, S.; Winters, T. J.; Burslem, G.; Sgourakis, N. G.
10.1101/2023.03.18.533266 — biochemistry — Posted on 2023-03-18
2060 Motor nerves direct the development of the sympathetic nervous system
Erickson, A. G.; Motta, A.; Kastriti, M. E.; Edwards, S.; Lallemend, F.; Hadjab, S.; Ruhrberg, C.; Schwarz, Q.; Fried, K.; Bonanomi, D.; Adameyko, I. I.
10.1101/2023.03.17.533145 — developmental biology — Posted on 2023-03-18
2062 Tracking Early Mammalian Organogenesis - Prediction and Validation of Differentiation Trajectories at Whole Organism Scale
Gottgens, B.; de Bruijn, M.; Marioni, J. C.; Nichols, J.; Calero-Nieto, F. J.; Argelaguet, R.; Keitley, D.; Dhapola, P.; Ton, M.-L. N.; Guibentif, C.; Rode, C.; Imaz Rosshandler, I.
10.1101/2023.03.17.532833 — developmental biology — Posted on 2023-03-18
2063 Breaking the C. elegans invasion/proliferation dichotomy
Martinez, M. A. Q.; Zhao, C.; Moore, F. E. Q.; Yee, C. S.; Zhang, W.; Shen, K.; Martin, B. L.; Matus, D. Q.
10.1101/2023.03.16.533034 — developmental biology — Posted on 2023-03-18
2064 Notch1 forms nuclear transcriptional condensates that drive target gene expression.
Foran, G.; Hallam, R. D.; Megaly, M.; Turgambayeva, A.; Li, Y.; Necakov, A.
10.1101/2023.03.17.533124 — cell biology — Posted on 2023-03-18
2065 Harnessing PROTAC technology to combat stress hormone receptor activation
Gazorpak, M.; Hungentobler, K. M.; Dominique, P.; Germain, P.-L.; Mathis, K.; Rudolf, R.; Barrenechea, S. M.; Kretschmer, M.; Fischer, V. V.; Xue, X.; Privitera, M.; Ivanova, I.; Hierlemann, A.; Meijer, O. C.; Carreira, E. M.; Bohacek, J.; Gapp, K.
10.1101/2023.03.17.533120 — molecular biology — Posted on 2023-03-18
2066 Whole-genomes from the extinct Xerces Blue butterfly can help identify declining insect species
de-Dios, T.; Fontsere, C.; Renom, P.; Stiller, J.; Llovera, L.; Uliano-Silva, M.; Sanchez-Gracia, A.; Wright, C.; Lizano, E.; Navarro, A.; Civit, S.; Robbins, R. K.; Blaxter, M.; Marques-Bonet, T.; Vila, R.; Lalueza-Fox, C.
10.1101/2021.11.08.467457 — evolutionary biology — Posted on 2023-03-18
2068 The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
Nasir, A.; Camacho, S.; McIntosh, A. T.; Graham, G. T.; Rahhal, R.; Huysman, M. E.; Alsharief, F.; Riegel, A. T.; Pearson, G. W.
10.1101/2020.11.14.383232 — cancer biology — Posted on 2023-03-18
2069 Unexpected contributions of striatal projection neurons coexpressing dopamine D1 and D2 receptors in balancing motor control
Bonnavion, P.; Varin, C.; Fakhfouri, G.; Martinez Olondo, P.; De Groote, A.; Cornil, A.; Lorenzo Lopez, R.; Pozuelo Fernandez, E.; Isingrini, E.; Rainer, Q.; Xu, K.; Tzavara, E.; Vigneault, E.; Dumas, S.; de Kerchove d'Exaerde, A.; GIROS, B.
10.1101/2022.04.05.487163 — neuroscience — Posted on 2023-03-18
2071 OPTIMAL: An OPTimsed Imaging Mass cytometry AnaLysis framework for Segmentation and Data Exploration
Hunter, B.; Nicorescu, I.; Foster, E.; McDonald, D.; Hulme, G.; Fuller, A.; Thomson, A.; Hilkens, C.; Majo, J.; Milross, L.; Fisher, A. J.; Wills, J. W.; Rees, P.; Filby, A.; Merces, G.
10.1101/2023.02.21.526083 — bioinformatics — Posted on 2023-03-18
2073 Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants
Dragwidge, J. M.; Wang, Y.; Brocard, L.; De Meyer, A.; Hudecek, R.; Eeckhout, D.; Grones, P.; Buridan, M.; Chambaud, C.; Pejchar, P.; Potocky, M.; Winkler, J.; Vandorpe, M.; Serre, N.; Fendrych, M.; Bernard, A.; De Jaeger, G.; Pleskot, R.; Fang, X.; Van Damme, D.
10.1101/2022.03.17.484738 — cell biology — Posted on 2023-03-18
2074 S-EBM: Generalising event-based modelling of disease progression for simultaneous events
Parker, C. S.; Oxtoby, N. P.; Alexander, D. C.; Zhang, H.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2022.07.10.499471 — neuroscience — Posted on 2023-03-18
2075 Genomic signatures of past and present chromosomal instability in the evolution of Barretts esophagus to esophageal adenocarcinoma
Zhang, C.-Z.; Stachler, M.; Bao, C.; Tourdot, R.; Brunette, G. J.; Stewart, C.; Sun, L.; Baba, H.; Watanabe, M.; Agoston, A.; Jajoo, K.; Nason, K.; Davison, J.; Getz, G.; Wang, K.; Imamura, Y.; Odze, R.; Bass, A.
10.1101/2021.03.26.437288 — cancer biology — Posted on 2023-03-18
2076 TF-Prioritizer: a java pipeline to prioritize condition-specific transcription factors
Hoffmann, M.; Trummer, N.; Schwartz, L.; Jankowski, J.; Lee, H. K.; Willruth, L.-L.; Yuan, K.; Lazareva, O.; Baumgarten, N.; Schmidt, F.; Baumbach, J.; Schulz, M. H.; Blumenthal, D. B.; Hennighausen, L.; List, M.
10.1101/2022.10.19.512881 — bioinformatics — Posted on 2023-03-18
2078 A human embryonic limb cell atlas resolved in space and time
Zhang, B.; He, P.; Lawrence, J. E.; Wang, S.; Tuck, E.; Williams, B. A.; Roberts, K.; Kleshchevnikov, V.; Mamanova, L.; Bolt, L.; Polanski, K.; Elmentaite, R.; Fasouli, E. S.; Prete, M.; He, X.; Yayon, N.; Fu, Y.; Yang, H.; Liang, C.; Zhang, H.; Fitzpatrick, D.; Firth, H.; Dean, A.; Marioni, J.; Barker, R. A.; Storer, M. A.; Wold, B.; Zhang, H.; Teichmann, S.; Marioni, J. C.; Blain, R.; Chedotal, A.
10.1101/2022.04.27.489800 — developmental biology — Posted on 2023-03-18
2079 Multi-omics approach reveals dysregulated genes during hESCs neuronal differentiation exposure to paracetamol
Spildrejorde, M.; Samara, A.; Sharma, A.; Leithaug, M.; Falck, M.; Modafferi, S.; Sundaram, A.; Acharya, G.; Nordeng, H.; Eskeland, R.; Gervin, K.; Lyle, R.
10.1101/2022.12.08.519620 — cell biology — Posted on 2023-03-18
2081 Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry
Phulphagar, K.; Ctortecka, C.; Vaca, S.; Klaeger, S.; Verzani, E. K.; Hernandez, G. M.; Udeshi, N.; Clauser, K. R.; Abelin, J.; Carr, S. A.
10.1101/2023.03.10.532106 — immunology — Posted on 2023-03-18
2082 Decision uncertainty as a context for motor memory
Ogasa, K.; Yokoi, A.; Okazawa, G.; Nishigaki, M.; Hirashima, M.; Hagura, N.
10.1101/2023.03.15.532761 — neuroscience — Posted on 2023-03-18
2086 Library size confounds biology in spatial transcriptomics data
Bhuva, D. D.; Tan, C. W.; Marceaux, C.; Chen, J.; Kharbanda, M.; Jin, X.; Liu, N.; Feher, K.; Putri, G.; Asselin-Labat, M.-L.; Phipson, B.; Davis, M. J.
10.1101/2023.03.15.532733 — bioinformatics — Posted on 2023-03-18
2088 Intracellular biotransformation and disposal mechanisms of magnetosomes in macrophages and cancer cells
Gandarias, L.; G. Gubieda, A.; Gorni, G.; Mathon, O.; Olivi, L.; Abad-Diaz-de-Cerio, A.; Fdez-Gubieda, M. L.; Muela, A.; Garcia-Prieto, A.
10.1101/2023.03.15.532722 — biochemistry — Posted on 2023-03-18
2089 Split-Transformer Impute (STI): Genotype Imputation Using a Transformer-Based Model
Mowlaei, M. E.; Li, C.; Chen, J.; Jamialahmadi, B.; Kumar, S.; Rebbeck, T. R.; Shi, X.
10.1101/2023.03.05.531190 — genomics — Posted on 2023-03-18
2092 Cysteine-Rich Intestinal Protein 1 is a Novel Surface Marker for Myometrial Stem/Progenitor Cells.
Paul, E. N.; Carpenter, T. J.; Fitch, S.; Sheridan, R.; Lau, K. H.; Arora, R.; Teixeira, J. M.
10.1101/2023.02.20.529273 — developmental biology — Posted on 2023-03-18
2093 Aging Atlas Reveals Cell-Type-Specific Regulation of Pro-longevity Strategies
Gao, S. M.; Qi, Y.; Zhang, Q.; Mohammed, A. S.; Lee, Y.-T.; Guan, Y.; Li, H.; Fu, Y.; Wang, M. C.
10.1101/2023.02.28.530490 — developmental biology — Posted on 2023-03-18
2094 Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis
Watanuki, S.; Kobayashi, H.; Sugiura, Y.; Yamamoto, M.; Karigane, D.; Shiroshita, K.; Sorimachi, Y.; Koide, S.; Oshima, M.; Nishiyama, A.; Murakami, K.; Miho, H.; Tamaki, S.; Yamamoto, T.; Yabushita, T.; Tanaka, Y.; Honda, H.; Okamoto, S.; Goda, N.; Tamura, T.; Nakamura-Ishizu, A.; Suematsu, M.; Iwama, A.; Suda, T.; Takubo, K.
10.1101/2023.03.16.532898 — cell biology — Posted on 2023-03-18
2095 Pyochelin biotransformation by Staphylococcus aureus shapes bacterial competition with Pseudomonas aeruginosa in polymicrobial infections
Jenul, C.; Keim, K.; Jens, J.; Zeiler, M. J.; Schilcher, K.; Schurr, M.; Melander, C.; Phelan, V. V.; Horswill, A. R.
10.1101/2022.04.18.486787 — microbiology — Posted on 2023-03-18
2096 Further evidences of an emerging stingless bee-yeast symbiosis
de Paula, G. T.; Melo, W. G. P.; de Castro, I.; Menezes, C.; Paludo, C. R.; Rosa, C. A.; Pupo, M. T.
10.1101/2023.03.08.531834 — microbiology — Posted on 2023-03-18
2098 Leaf-level metabolic changes in response to drought affect daytime CO2 emission and isoprenoid synthesis pathways
Ladd, S. N.; Daber, L. E.; Bamberger, I.; Kuebert, A.; Kreuzwieser, J.; Purser, G.; Ingrisch, J.; Deleeuw, J.; van Haren, J.; Meredith, L.; Werner, C.
10.1101/2022.04.29.490001 — plant biology — Posted on 2023-03-18
2099 Variation in microbial feature perception in the Rutaceae family with immune receptor conservation in citrus
Trinh, J.; Li, T.; Franco, J. Y.; Toruno, T. Y.; Stevens, D. M.; Thapa, S. P.; Wong, J.; Pineda, R.; Avila de Dios, E.; Kahn, T. L.; Seymour, D. K.; Ramadugu, C.; Coaker, G. L.
10.1101/2022.07.15.500235 — plant biology — Posted on 2023-03-18
2101 At-home bacteria collection using CandyCollect, a lollipop-inspired device
Tu, W.-c.; McManamen, A. M.; Su, X.; Jeacopello, I.; Takezawa, M. G.; Hieber, D. L.; Hassan, G. W.; Lee, U. N.; Anana, E. V.; Locknane, M. P.; Stephenson, M. W.; Shinkawa, V. A. M.; Wald, E. R.; DeMuri, G. P.; Adams, K.; Berthier, E.; Thongpang, S.; Theberge, A. B.
10.1101/2023.01.14.524039 — biochemistry — Posted on 2023-03-18
2104 Sex-specific transcript diversity is regulated by a maternal pioneer factor in early Drosophila embryos
Ray, M.; Conard, A. M.; Urban, J.; Aguilera, J.; Huang, A.; Mahableshwarkar, P.; Vaidyanathan, S.; Larschan, E.
10.1101/2021.03.18.436074 — genomics — Posted on 2023-03-18
2108 The Features Underlying the Memorability of Objects
Kramer, M. A.; Hebart, M. N.; Baker, C. I.; Bainbridge, W. A.
10.1101/2022.04.29.490104 — neuroscience — Posted on 2023-03-18
2110 Determinants of genetic diversity in sticklebacks
Kivikoski, M.; Feng, X.; Loytynoja, A.; Momigliano, P.; Merila, J.
10.1101/2023.03.17.533073 — evolutionary biology — Posted on 2023-03-17
2113 DNA virus BdDV-1 of the amphibian pathogen Batrachochytrium dendrobatidis is associated with hypervirulence
Clemmons, R.; Yacoub, M.; Faust, E.; Toledo, L. F.; Jenkinson, T. S.; Kalinka, E.; Fritz-Laylin, L. K.; James, T. Y.; Stajich, J. E.
10.1101/2023.03.16.532857 — microbiology — Posted on 2023-03-17
2114 TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation
Peters, T.; Muehlgrabner, V.; Velasco Cardenas, R. M. H.; Platzer, R.; Gohring, J.; Salzer, B.; Plach, A.; Hoehrhan, M.; Doel-Perez, I.; Goncalves, V. D. R.; Farfan, J. S.; Lehner, M.; Stockinger, H.; Schamel, W. W.; Schober, K.; Busch, D. H.; Hudecek, M.; Dushek, O.; Minguet, S.; Huppa, J. B.
10.1101/2023.03.16.532775 — immunology — Posted on 2023-03-17
2115 The relationship between object-based spatial ability and virtual navigation performance
Garg, T.; Velasco, P. F.; Patai, Z. E.; Malcolm, C. P.; Kovalets, V.; Bohbot, V. D.; Coutrot, A.; Hegarty, M.; Hornberger, M.; Spiers, H. J.
10.1101/2023.03.16.532962 — neuroscience — Posted on 2023-03-17
2116 Uncovering the Morphological Evolution of Language-Relevant Brain Areas
Gallardo, G.; Eichner, C.; Sherwood, C. C.; Hopkins, W. D.; Anwander, A.; Friederici, A. D.
10.1101/2023.03.17.533103 — neuroscience — Posted on 2023-03-17
2118 Ultra-high throughput mapping of genetic design space
O'Connell, R. W.; Rai, K.; Piepergerdes, T. C.; Samra, K. D.; Wilson, J. A.; Lin, S.; Zhang, T. H.; Ramos, E.; Sun, A.; Kille, B.; Curry, K. D.; Rocks, J. W.; Treangen, T. J.; Mehta, P.; Bashor, C. J.
10.1101/2023.03.16.532704 — synthetic biology — Posted on 2023-03-17
2120 Magnipore: Prediction of differential single nucleotide changes in the Oxford Nanopore Technologies sequencing signal of SARS-CoV-2 samples
Spangenberg, J.; Honer zu Siederdissen, C.; Zarkovic, M.; Triebel, S.; Rose, R.; Martinez Christophersen, C. V.; Paltzow, L.; Hegab, M. M.; Wansorra, A. N.; Srivastava, A.; Krumbholz, A.; Marz, M.
10.1101/2023.03.17.533105 — bioinformatics — Posted on 2023-03-17
2121 BCL7 proteins, metazoan-specific subunits of the mammalian SWI/SNF complex, bind the nucleosome core particle
Diaz, D.; Kazrani, A. A.; Martin, F.; Lafouge, J.; Siebert, S.; Birck, C.; Blais, A.; Bergamin, E.
10.1101/2023.03.17.532992 — biochemistry — Posted on 2023-03-17
2123 Gene recoding by synonymous mutations creates promiscuous intragenic transcription initiation in mycobacteria
Hegelmeyer, N. K.; Previti, M. L.; Andrade, J.; Utama, R.; Sejour, R. J.; Gardin, J.; Muller, S.; Ketchum, S.; Yurovsky, A.; Futcher, B.; Goodwin, S.; Ueberheide, B.; Seeliger, J.
10.1101/2023.03.17.532606 — molecular biology — Posted on 2023-03-17
2126 Reference mouse strain assemblies for BALB/c Nude and NOD/SCID mouse models
Schmid-Siegert, E.; Quin, M.; Tian, H.; Arpat, B.; Chen, B.; Xenarios, I.
10.1101/2023.03.16.532783 — genomics — Posted on 2023-03-17
2127 6mA-Sniper: Quantifying 6mA Sites in Eukaryotes at Single-Nucleotide Resolution
Zhang, J.; Peng, Q.; Ma, C.; Wang, J.; Xiao, C.; Li, T.; Liu, X.; Zhou, L.; Zhou, W.-Z.; Ding, W.; An, N. A.; Zhang, L.; Liu, Y.; Li, C.-Y.
10.1101/2023.03.16.530559 — genomics — Posted on 2023-03-17
2129 Airway epithelial response to RSV is impaired in multiciliated and goblet cells in asthma
Gay, A. C. A.; Banchero, M.; Carpaij, O. A.; Kole, T.; Apperloo, L.; van Gosliga, D.; Fajar, P. A.; Koppelman, G. H.; Bont, L.; Hendriks, R. W.; van den Berge, M.; Nawijn, M. C.
10.1101/2023.03.16.532356 — molecular biology — Posted on 2023-03-17
2130 Pangenomes reveal genomic signatures of microbial adaptation to chronic soil warming
Choudoir, M. J.; Narayanan, A.; Rodriguez-Ramos, D.; Simoes, R.; Efroni, A.; Sondrini, A.; DeAngelis, K. M.
10.1101/2023.03.16.532972 — microbiology — Posted on 2023-03-17
2131 Development of safe and effective bacteriophage-mediated therapies against C. difficile infections a proof-of-concept preclinical study
Rasmussen, T. S.; Forster, S.; Larsen, S. B.; von Munchow, A.; Tranaes, K. D.; Brunse, A.; Castro-Mejia, J. L.; Adamberg, S.; Hansen, A. K.; Adamberg, K.; Hansen, C. H. F.; Nielsen, D. S.
10.1101/2023.03.17.532897 — microbiology — Posted on 2023-03-17
2134 SYNTHETIC CIRCUITS BASED ON SPLIT CAS9 TO DETECT CELLULAR EVENTS
Przybyszewska-Podstawka, A.; Czapinski, J.; Kalafut, J.; Rivero-Muller, A.
10.1101/2023.03.16.533022 — synthetic biology — Posted on 2023-03-17
2137 THE RIBOREGULATION MECHANISM OF HUMAN SERINE HYDROXYMETHYLTRANSFERASE IS ROOTED IN AN ALLOSTERIC SWITCH
Spizzichino, S.; Di Fonzo, F.; Marabelli, C.; Tramonti, A.; Chaves-Sanjuan, A.; Parroni, A.; Boumis, G.; Liberati, F. R.; Paone, A.; Montemiglio, L. C.; Ardini, M.; Jakobi, A. J.; Bharadwaj, A.; Swuec, P.; Tartaglia, G. G.; Paiardini, A.; Contestabile, R.; Rinaldo, S.; Bolognesi, M.; Giardina, G.; Cutruzzola, F.
10.1101/2023.03.17.532973 — biochemistry — Posted on 2023-03-17
2138 Human Gut Microbial Sulfonolipids are linked to Inflammatory Bowel Diseases through Toll-Like Receptor 4 Signaling
Older, E. A.; Zhang, J.; Ferris, Z. E.; Xue, D.; Zhong, Z.; Mitchell, M. K.; Michael, M.; Wang, Y.; Chen, H.; Nagarkatti, P.; Nagarkatti, M.; Fan, D.; Ellermann, M.; LI, Y.; Li, J.
10.1101/2023.03.16.533047 — biochemistry — Posted on 2023-03-17
2139 The power and limitations of species tree-aware phylogenetics
Williams, T. A.; Davin, A. A.; Morel, B.; Szantho, L. L.; Spang, A.; Stamatakis, A.; Hugenholtz, P.; Szollosi, G. J.
10.1101/2023.03.17.533068 — evolutionary biology — Posted on 2023-03-17
2142 Parallel genetic adaptation of Bacillus subtilis to different plant species
Hu, G.; Wang, Y.; Blake, C.; Nordgaard, M.; Liu, X.; Wang, B.; Kovacs, A. T.
10.1101/2023.03.17.533125 — microbiology — Posted on 2023-03-17
2143 The energy landscape for R-loop formation by the CRISPR-Cas Cascade complex
Kauert, D. J.; Madariaga Marcos, J.; Rutkauskas, M.; Wulfken, A.; Songailiene, I.; Sinkunas, T.; Siksnys, V.; Seidel, R.
10.1101/2023.03.17.533087 — biophysics — Posted on 2023-03-17
2144 Rapid and accurate deorphanization of ligand-receptor pairs using AlphaFold
Banhos Danneskiold-Samsoee, N.; Kavi, D.; Jude, K. M.; Nissen, S. B.; Wat, L. W.; Coassolo, L.; Zhao, M.; Asae Santana-Oikawa, G.; Broido, B. B.; Garcia, K. C.; Svensson, K. J.
10.1101/2023.03.16.531341 — biochemistry — Posted on 2023-03-17
2145 A general computational design strategy for stabilizing viral class I fusion proteins
Gonzalez, K. J.; Huang, J.; Criado, M. F.; Banerjee, A.; Tompkins, S. M.; Mousa, J. J.; Strauch, E. M.
10.1101/2023.03.16.532924 — microbiology — Posted on 2023-03-17
2146 Antibodies generated in vitro and in vivo elucidate design of a thermostable ADDomer COVID-19 nasal nanoparticle vaccine
Buzas, D.; Bunzel, H. A.; Staufer, O.; Milodowski, E.; Edmonds, G.; Vidana Matteo, b.; Berger Schaffitzel, C.; Yadav, S.; Gupta, K.; Fletcher, C.; Kavanagh Williamson, M.; Harrison, A.; Borucu, U.; Capin, J.; Francis, O.; Balchin, G.; Hall, S.; Vivoli Vega, M.; Durbesson, F.; Vincentelli, R.; Roe, J.; Wooldridge, L.; Burt, R.; Anderson, R.; Mulholland, A. J.; Hare, J.; Bailey, M.; Davidson, A.; Finn, A.; Morgan, D.; Mann, J.; SPatz, J.; Garzoni, F.; Bufton, J.; Berger, I.
10.1101/2023.03.17.533092 — biochemistry — Posted on 2023-03-17
2148 FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55/PP2A phosphatase
Wasserman, J. S.; Faezov, B.; Patel, K. R.; Kurimchak, A. M.; Palacio, S.; Fowle, H.; McEwan, B. C.; Xu, Q.; Zhao, Z.; Cressey, L.; Johnson, N.; Duncan, J. S.; Kettenbach, A. S.; Dunbrack, R. L.; Grana, X.
10.1101/2023.03.06.531310 — molecular biology — Posted on 2023-03-17
2151 Non-visual camouflage predicts hunting success in a wild predator
Schalcher, K.; Milliet, E.; Sechaud, R.; Buehler, R.; Almasi, B.; Pottier, S.; Becciu, P.; Roulin, A.; Shepard, E. L. C.
10.1101/2023.03.07.531523 — animal behavior and cognition — Posted on 2023-03-17
2152 Accurate delineation of individual tree crowns in tropical forests from aerial RGB imagery using Mask R-CNN
Ball, J. G. C.; Hickman, S. H. M.; Jackson, T. D.; Koay, X. J.; Hirst, J.; Jay, W.; Archer, M.; Aubry-Kientz, M.; Vincent, G.; Coomes, D. A.
10.1101/2022.07.10.499480 — ecology — Posted on 2023-03-17
2153 A lymph node-to-tumour PD-L1+macrophage circuit antagonizes dendritic cell immunotherapy
Sprooten, J.; Vanmeerbeek, I.; Datsi, A.; Govaerts, J.; Borras, D.; Naulaerts, S.; Laureano, R.; Calvet, A.; Kuballa, M.; Sabel, M.; Rapp, M.; Knobbe-Thomsen, C.; Liu, P.; Zhao, L.; Kepp, O.; Kroemer, G.; Boon, L.; Tejpar, S.; Borst, J.; Schlenner, S.; De Vleeschouwer, S.; Sorg, R.; Garg, A. D.
10.1101/2023.03.14.532534 — immunology — Posted on 2023-03-17
2154 Large tissue archiving solution for multiplexed labeling and super-resolution imaging
Lin, Y.-H.; Wang, L.-W.; Chen, Y.-H.; Chan, Y.-C.; Hu, S.-H.; Wu, S.-Y.; Chiang, C.-S.; Huang, G.-J.; Yang, S.-D.; Chu, S.-W.; Wang, K.-C.; Lin, C.-H.; Huang, P.-H.; Cheng, H.-J.; Chen, B.-C.; Chu, L.-A.
10.1101/2022.11.28.518189 — neuroscience — Posted on 2023-03-17
2155 Altered hierarchical auditory predictive processing after lesions to the orbitofrontal cortex
Asko, O.; Blenkmann, A. O.; Leske, S. L.; Foldal, M. D.; Llorens, A.; Funderud, I.; Meling, T. R.; Knight, R. T.; Endestad, T.; Solbakk, A.-K.
10.1101/2023.01.04.521570 — neuroscience — Posted on 2023-03-17
2156 Sulfolactaldehyde dehydrogenase of Rhizobium leguminosarum: Kinetic and structural analysis
Li, J.; Sharma, M.; Meek, R. W.; Alhifthi, A.; Armstrong, Z.; Madiedo Soler, N.; Goddard-Borger, E. D.; Blaza, J. N.; Davies, G. J.; Williams, S. J.
10.1101/2023.03.13.532361 — biochemistry — Posted on 2023-03-17
2157 One Health Assessment of an Urban Temporary Settlement Reveals Gut Microbiome Serving as Antimicrobial Resistance Gene Reservoir
Napit, R.; Gurung, A.; Poudel, A.; Manandhar, P.; Chaudhary, A. B.; Sharma, A. N.; Raut, S.; Pradhan, S. M.; Joshi, J.; Poyet, M.; Groussin, M.; Rajbhandari, R. M.; Karmacharya, D.
10.1101/2023.03.15.532708 — genomics — Posted on 2023-03-17
2158 Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior
Barron, J. J.; Mroz, N. M.; Taloma, S. E.; Dahlgren, M. W.; Ortiz-Carpena, J. F.; Dorman, L. C.; Vainchtein, I. D.; Escoubas, C. C.; Molofsky, A. B.; Molofsky, A. V.
10.1101/2023.03.16.532850 — neuroscience — Posted on 2023-03-17
2159 Keypoint-MoSeq: parsing behavior by linking point tracking to pose dynamics
Weinreb, C.; Osman, M. A. M.; Zhang, L.; Lin, S.; Pearl, J.; Annapragada, S.; Conlin, E.; Gillis, W. F.; Jay, M.; Ye, S.; Mathis, A.; Mathis, M. W.; Pereira, T.; Linderman, S. W.; Datta, S. R.
10.1101/2023.03.16.532307 — neuroscience — Posted on 2023-03-17
2160 Simple and highly efficient detection of PSD95 using a nanobody and its re-combinant minibody derivative
Kilisch, M.; Gere-Becker, M.; Wüstefeld, L.; Bonnas, C.; Crauel, A.; Mechmershausen, M.; Martens, H.; Götzke, H.; Opazo, F.; Frey, S.
10.1101/2023.03.16.532938 — neuroscience — Posted on 2023-03-17
2163 Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism.
Yamashita, A.; Ignatenko, O.; Nguyen, M.; Lambert, R.; Watt, K.; Daneault, C.; Robillard-Frayne, I.; Topisirovic, I.; Des Rosiers, C.; McBride, H. M.
10.1101/2023.03.15.532715 — cell biology — Posted on 2023-03-17
2164 CLN3 deficiency leads to neurological and metabolic perturbations during early development
Heins-Marroquin, U.; Singh, R. R.; Perathoner, S.; Gavotto, F.; Merino Ruiz, C.; Patraskaki, M.; Gomez-Giro, G.; Kleine Borgmann, F.; Meyer, M.; Carpentier, A.; Warmoes, M. O.; Jaeger, C.; Mittelbronn, M.; Schwamborn, J. C.; Cordero-Maldonado, M. L.; Crawford, A. D.; Schymanski, E. L.; Linster, C. L.
10.1101/2023.03.17.533107 — molecular biology — Posted on 2023-03-17
2165 Novel kinetoplastid-specific cAMP binding proteins identified by RNAi screening for cAMP resistance in T. brucei
Bachmaier, S.; Gould, M. K.; Polatoglou, E.; Omelianczyk, R.; Brennand, A.; Aloraini, M. A.; Munday, J. C.; Horn, D.; Boshart, M.; De Koning, H. P.
10.1101/2023.03.14.532707 — microbiology — Posted on 2023-03-17
2166 Clec12a tempers inflammation while restricting expansion of a colitogenic commensal
Round, J.; Chiaro, T.; Bauer, K.; Ost, K.; Stephen-Victor, E.; Nelson, M.; Hill, J. H.; Bell, R.; Harwood, M.; Voth, W.; Jackson, T.; Klag, K.; O'Connell, R.; Stephens, W. Z.
10.1101/2023.03.16.532997 — immunology — Posted on 2023-03-17
2167 NAC1 directs CEP1-CEP3 peptidase expression and decreases cell wall extensins linked to root hair growth in Arabidopsis
Rodriguez-Garcia, D. R.; Marzol, E.; Rondon Guerrero, Y. d. C.; Ferrero, L. V.; Rossi, A. H.; Miglietta, E. A.; Aptekmann, A. A.; Martinez Pacheco, J.; Carignani, M.; Berdion Gabarain, V.; Lopez, L. E.; Diaz Dominguez, G.; Sanchez-Serrano, J. J.; Xu, L.; Nadra, A. D.; Ariel, F. D.; Rojo, E.; Estevez, J.
10.1101/2023.03.15.532802 — plant biology — Posted on 2023-03-17
2168 High prevalence and dependence of centrosome clustering in mesenchymal tumors and leukemia
Marin, N. M.; Marteil, G.; Fresmann, N. C.; de Almeida, B. P.; Dores, K.; Fragoso, R.; Vaz, J. C.; Leal, J. B. P.; Taborda Barata, J. P.; Godinho, S. A.; Barbosa-Morais, N. L.; Bettencourt-Dias, M.
10.1101/2023.03.13.532472 — cancer biology — Posted on 2023-03-17
2169 Targeted proteomic quantitation of NRF2 signaling and predictive biomarkers in HNSCC
Wamsley, N.; Wilkerson, E.; Guan, L.; LaPak, K.; Schrank, T.; Holmes, B.; Sprung, R.; Gilmore, P. E.; Gerndt, S.; Jackson, R.; Paniello, R.; Pipkorn, P.; Puram, S. V.; Rich, J.; Townsend, R. R.; Zevallos, J.; Zolkind, P.; Le, Q.-T.; Goldfarb, D.; Major, M. B.
10.1101/2023.03.13.532474 — cancer biology — Posted on 2023-03-17
2171 Tissue-engineered models of lung cancer premalignancy
Blomberg, R.; Sompel, K.; Hauer, C.; Pena, B.; Driscoll, J.; Hume, P. S.; Merrick, D. T.; Tennis, M. A.; Magin, C. M.
10.1101/2023.03.15.532835 — bioengineering — Posted on 2023-03-17
2173 Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
Traphagen, N. A.; Schwartz, G. N.; Tau, S.; Jiang, A.; Hosford, S. R.; Goen, A. E.; Roberts, A. M.; Romo, B. A.; Johnson, A. L.; Duffy, E.-C. K.; Demidenko, E.; Heverly, P.; Mosesson, Y.; Soucy, S. M.; Kolling, F.; Miller, T. W.
10.1101/2023.03.16.532956 — cancer biology — Posted on 2023-03-17
2177 Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types
McCormack, C. P.; Yan, A. W. C.; Brown, J. C.; Sukhova, K.; Peacock, T. P.; Barclay, W. S.; Dorigatti, I.
10.1101/2023.03.15.529513 — microbiology — Posted on 2023-03-17
2178 Type-specific EV-D68 real-time RT-PCR assay for the detection of all extant enterovirus D68 strains
Ng, T. F. F.; Nix, W. A.; Rogers, S.; Emery, B.; Chern, S.-W.; Butler, K.; Oberste, M. S.
10.1101/2022.10.06.511205 — microbiology — Posted on 2023-03-17
2181 A gene essentiality signature enables predicting the mechanism of action of drugs
Wang, W.; Bao, J.; Zheng, S.; Huang, S.; Aldahdooh, J.; Wang, Y.; Eriksson, J. T.; Tanoli, Z.; Zhang, X.; Gaetani, M.; Tang, J.
10.1101/2022.11.07.514541 — systems biology — Posted on 2023-03-17
2185 Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker
Taylor, M. S.; Connie, W.; Fridy, P. C.; Zhang, S. J.; Senussi, Y.; Wolters, J. C.; Cheng, W.-C.; Heaps, J.; Miller, B. D.; Mori, K.; Cohen, L.; Jiang, H.; Molloy, K. R.; Norden, B. L.; Chait, B. T.; Goggins, M.; Bhan, I.; Franses, J. W.; Yang, X.; Taplin, M.-E.; Wang, X.; Christiani, D. C.; Johnson, B. E.; Meyerson, M.; Uppaluri, R.; Egloff, A. M.; Denault, E. N.; Spring, L. M.; Wang, T.-L.; Shih, I.-M.; Jung, E.; Arora, K. S.; Zukerberg, L. R.; Yilmaz, O. H.; Chi, G.; Matulonis, U. A.; Song, Y.; Nieman, L.; Parikh, A. R.; Strickland, M.; Corcoran, R. B.; Mustelin, T.; Eng, G.; Yilmaz, O. H.;
10.1101/2023.01.25.525462 — cancer biology — Posted on 2023-03-17
2190 Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway
Kim, J.-i.; Miura, Y.; Li, M.-Y.; Revah, O.; Selvaraj, S.; Birey, F.; Meng, X.; Thete, M. V.; Pavlov, S. D.; Anderson, J.; Pasca, A. M.; Porteus, M. H.; Huguenard, J. R.; Pasca, S. P.
10.1101/2023.03.15.530726 — neuroscience — Posted on 2023-03-17
2191 Transitions between cognitive topographies: contributions of network structure, neuromodulation, and disease
Luppi, A. I.; Singleton, S. P. I.; Hansen, J. Y.; Bzdok, D.; Kuceyeski, A.; Betzel, R.; Misic, B.
10.1101/2023.03.16.532981 — neuroscience — Posted on 2023-03-17
2193 Hardwired to attack: Transcriptionally defined amygdala subpopulations play distinct roles in innate social behaviors.
Lischinsky, J. E.; Yin, L.; Shi, C.; Prakash, N.; Burke, J.; Shekaran, G.; Grba, M.; Corbin, J. G.; Lin, D.
10.1101/2023.03.16.532692 — neuroscience — Posted on 2023-03-17
2194 General and specific patterns of cortical gene expression as substrates of complex cognitive functioning
Moodie, J. E.; Harris, S. E.; Harris, M. A.; Buchanan, C. R.; Davies, G.; Taylor, A.; Redmond, P.; Liewald, D.; Valdes Hernandez, M. D.; Shenkin, S. D.; Russ, T. C.; Munoz Maniega, S. C.; Luciano, M.; Corley, J.; Stolicyn, A.; Shen, X.; Steele, D.; Waiter, G.; Sandu-Giuraniuc, A.; Bastin, M.; Wardlaw, J.; McIntosh, A. M.; Whalley, H. C.; Tucker-Drob, E. M.; Deary, I.; Cox, S. R.
10.1101/2023.03.16.532915 — neuroscience — Posted on 2023-03-17
2201 Evolution of chemosensory and detoxification gene families across herbivorous Drosophilidae
Pelaez, J. N.; Gloss, A. D.; Goldman-Huertas, B.; Kim, B.; Lapoint, R. T.; Pimentel-Solorio, G.; Verster, K. I.; Aguilar, J. M.; Dittrich, A. C. N.; Singhal, M.; Suzuki, H. C.; Matsunaga, T.; Armstrong, E. E.; Charboneau, J. L. M.; Groen, S. C.; Hembry, D. H.; Ochoa, C. J.; OConnor, T. K.; Prost, S.; Zaaijer, S.; Nabity, P. D.; Wang, J.; Rodas, E.; Liang, I.; Whiteman, N. K.
10.1101/2023.03.16.532987 — evolutionary biology — Posted on 2023-03-16
2202 The Ribosome Profiling landscape of yeast reveals a high diversity in pervasive translation
Papadopoulos, C.; Arbes, H.; Chevrollier, N.; Blanchet, S.; Cornu, D.; Roginski, P.; Rabier, C.; Atia, S.; Lespinet, O.; Namy, O.; Lopes, A.
10.1101/2023.03.16.532990 — evolutionary biology — Posted on 2023-03-16
2203 MBNL1 regulates programmed postnatal switching between regenerative and differentiated cardiac states.
Bailey, L. R. J.; Bugg, D.; Reichardt, I. M.; Ortac, C. D.; Gunaje, J.; Johnson, R.; MacCoss, M. J.; Sakamoto, T.; Kelly, D. P.; Regnier, M.; Davis, J. M.
10.1101/2023.03.16.532974 — cell biology — Posted on 2023-03-16
2205 Expanding the Characterization of Microbial Ecosystems using DIA-PASEF Metaproteomics
Gomez-Varela, D.; Xian, F.; Grundtner, S.; Sondermann, J. R.; Carta, G.; Schmidt, M.
10.1101/2023.03.16.532922 — microbiology — Posted on 2023-03-16
2206 TREM2 is downregulated by HSV1 in microglia and involved in antiviral defense in the brain
Fruhwurth, S.; Reinert, L.; Oberg, C.; Sakr, M.; Henricsson, M.; Zetterberg, H.; Paludan, S.
10.1101/2023.03.16.532882 — immunology — Posted on 2023-03-16
2207 Ingestion of Bacillus cereus spores dampens the immune response to favor bacterial persistence
Hachfi, S.; Brun-Barale, A.; Munro, P.; Nawrot-Esposito, M.-P.; Michel, G.; Fichant, A.; Bonis, M.; Ruimy, R.; Boyer, L.; GALLET, A.
10.1101/2023.03.16.532769 — immunology — Posted on 2023-03-16
2208 Single cell RNA sequencing in isogenic FUS and TARDBP mutant ALS lines reveals early mitochondrial dysfunction as a common pathway in motor neurons
Schweingruber, C.; Nijssen, J.; Mechtersheimer, J.; Reber, S.; Keuper, M.; Mei, I.; Aguila Benitez, J.; O'Brien, N.; Jastroch, M.; Ruepp, M.-D.; Hedlund, E.
10.1101/2023.03.16.531876 — neuroscience — Posted on 2023-03-16
2210 Clonal evolution mediates Menin-inhibitor resistance in KMT2A-rearranged leukemias.
Mahdavi, L.; Lenard, A.; Xie, H. M.; Alikarami, F.; Riedel, S. S.; Libbrecht, C.; Falkenstein, C.; Tasian, S. K.; Manning, B.; Skuli, S.; Carroll, M. P.; Wertheim, G.; McGeehan, G.; Bernt, K. M.
10.1101/2023.03.16.532874 — cancer biology — Posted on 2023-03-16
2211 Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15
Penengo, L.; Biswas, U.; Moro, R. N.; Kharat, S. S.; Das, P.; Chaudhuri, A. R.; Sharan, S. K.
10.1101/2023.03.16.533020 — cancer biology — Posted on 2023-03-16
2212 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α-primase
Mullins, E. A.; Salay, L. E.; Durie, C. L.; Jackman, J. E.; Ohi, M. D.; Chazin, W. J.; Eichman, B. F.
10.1101/2023.03.16.533013 — biochemistry — Posted on 2023-03-16
2214 Cancer mutations rewire the RNA methylation specificity of METTL3-METTL14
Zhang, C.; Tunes, L.; Hsieh, M.-H.; Wang, P.; Kumar, A.; Khadgi, B. B.; Yang, Y.-Y.; Doxtader, K. A.; Herrell, E.; Koczy, O.; Setlem, R.; Zhang, X.; Evers, B. M.; Wang, Y.; Xing, C.; Zhu, H.; Nam, Y.
10.1101/2023.03.16.532618 — biochemistry — Posted on 2023-03-16
2215 Reconstructing prehistoric viral genomes from Neanderthal sequencing data
Ferreira, R. C.; Alves, G. V.; Ramon, M.; Antoneli, F. M.; Briones, M. R.
10.1101/2023.03.16.532919 — genomics — Posted on 2023-03-16
2216 Adaptive host responses to infection can resemble parasitic manipulation
Haakonsrud Jensen, C.; Weidner, J.; Giske, J.; Joergensen, C.; Eliassen, S.; Mennerat, A.
10.1101/2023.03.16.532392 — evolutionary biology — Posted on 2023-03-16
2217 RHINO restricts MMEJ activity to mitosis
Sfeir, A.; Brambati, A.; Sacco, O.; Porcella, S.; Heyza, J. R.; Kareh, M.; Schmidt, J. C.
10.1101/2023.03.16.532763 — molecular biology — Posted on 2023-03-16
2218 DnaJC7 specifically regulates tau seeding
Perez, V. A.; Sanders, D. W.; Mendoza-Oliva, A.; Stopschinski, B. E.; Mullapudi, V.; White, C. L.; Joachimiak, L. A.; Diamond, M. I.
10.1101/2023.03.16.532880 — molecular biology — Posted on 2023-03-16
2219 Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration
Jones, A. C.; Kornev, A. P.; Weng, J.-H.; Manning, G. C.; Taylor, S. S.; Newton, A. C.
10.1101/2023.03.16.532226 — molecular biology — Posted on 2023-03-16
2223 Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes.
Hegde, S.; Brettell, L. E.; Quek, S.; Saldana, M. A.; Etebari, K.; Asgari, S.; Coon, K. L.; Heinz, E.; Hughes, G.
10.1101/2023.03.16.532926 — microbiology — Posted on 2023-03-16
2224 ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways
Rubina, A.; Patel, M.; Nightingale, K.; Potts, M.; Fielding, C. A.; Kollnberger, S.; Lau, B.; Ladell, K.; Miners, K. L.; Nichols, J.; Nobre, L.; Roberts, D.; Trinca, T. M.; Twohig, J. P.; Vlahava, V.-M.; Davison, A. J.; Price, D. A.; Tomasec, P.; Wilkinson, G. W. G.; Weekes, M. P. J.; Stanton, R. J.; Wang, E. C. Y.
10.1101/2023.03.16.532955 — microbiology — Posted on 2023-03-16
2225 Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation.
Raso, F.; Liu, S.; Willett, M. J.; Barton, G.; Mayer, C. T.; Bannard, O.; Acharya, M.; Muppidi, J.; Marshak-Rothstein, A.; Reboldi, A.
10.1101/2023.03.16.532481 — immunology — Posted on 2023-03-16
2229 Multiple sequence-alignment-based RNA language model and its application to structural inference
Zhang, Y.; Lang, M.; Jiang, J.; Gao, Z.; Xu, F.; Litfin, T.; Chen, K.; Singh, J.; Huang, X.; Song, G.; Tian, Y.; Zhan, J.; Chen, J.; Zhou, Y.
10.1101/2023.03.15.532863 — bioinformatics — Posted on 2023-03-16
2233 Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase
Alteen, M. G.; Meek, R. W.; Kolappan, S.; Busmann, J. A.; Cao, J.; O'Gara, Z.; Derda, R.; Davies, G. J.; Vocadlo, D. J.
10.1101/2023.03.15.532872 — biochemistry — Posted on 2023-03-16
2234 Identification of mammalian transcription factors that bind to inaccessible chromatin
Pop, R. T.; Pisante, A.; Nagy, D.; Martin, P. C. N.; Mikheeva, L. A.; Hayat, A.; Ficz, G.; Zabet, N. R.
10.1101/2023.03.15.532796 — genomics — Posted on 2023-03-16
2235 Shaken, not shifted: Genotypic variation tunes how interspecific competition shapes niches
Costa-Pereira, R.; Fragata, I.; Mira, A. F.; Masseliere, M. C. d. l.; Hortal, J.; Magalhaes, S.
10.1101/2023.03.15.532847 — ecology — Posted on 2023-03-16
2236 The Novel Silver-Containing Antimicrobial Potentiates Aminoglycoside Activity Against Pseudomonas aeruginosa.
Donkor, G. Y.; Anderson, G. M.; Stadler, M.; Tawiah, P. O.; Orellano, C. D.; Edwards, K. A.; Dahl, J.-U.
10.1101/2023.03.15.532855 — microbiology — Posted on 2023-03-16
2237 Identifying keystone species in microbial communities using deep learning
Wang, X.-W.; Sun, Z.; Jia, H.; Michel-Mata, S.; Angulo, M. T.; Dai, L.; He, X.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2023.03.15.532858 — microbiology — Posted on 2023-03-16
2238 Social association predicts immunological similarity in rewilded mice
Downie, A. E.; Oyesola, O.; Barre, R. S.; Caudron, Q.; Chen, Y.- H.; Dennis, E. J.; Garnier, R.; Kiwanuka, K.; Menezes, A.; Navarrete, D. J.; Mondragon-Palomino, O.; Saunders, J. B.; Tokita, C. K.; Zaldana, K.; Cadwell, K.; Loke, P.; Graham, A. L.
10.1101/2023.03.15.532825 — immunology — Posted on 2023-03-16
2239 Decision uncertainty as a context for motor memory
Ogasa, K.; Yokoi, A.; Okazawa, G.; Nishigaki, M.; Hirashima, M.; Hagura, N.
10.1101/2023.03.15.532761 — neuroscience — Posted on 2023-03-16
2242 HBV rewires liver cancer signaling by altering PP2A complexes
Pitea, A.; Turnham, R.; Eckhardt, M.; Jang, G. M.; Xu, Z.; Lim, H. C.; Choi, A.; Von Dollen, J.; Levin, R. S.; Webber, J. T.; McCarthy, E.; Hu, J.; Li, X.; Che, L.; Chan, G.; Kelley, R. K.; Swaney, D.; Zhang, W.; Bandyopadhyay, S.; Theis, F. J.; Chen, X.; Shokat, K.; Ideker, T.; Krogan, N. J.; Gordan, J.
10.1101/2023.03.15.532845 — cancer biology — Posted on 2023-03-16
2243 Remote neuronal activity drives glioma infiltration via Sema4f
Huang-Hobbs, E.; Cheng, Y.-T.; Ko, Y.; Luna-Figueroa, E.; Lozzi, B.; Taylor, K.; McDonald, M.; He, P.; Chen, H.-C.; Yang, Y.; Maleki, E.; Lee, Z.-F.; Murali, S.; Williamson, M.; Choi, D.; Curry, R.; Bayley, J.; Woo, J.; Jalali, A.; Monje, M.; Noebels, J. L.; Serin-Harmanci, A.; Rao, G.; Deneen, B.
10.1101/2023.03.15.532832 — cancer biology — Posted on 2023-03-16
2249 An Ensemble Penalized Regression Method for Multi-ancestry Polygenic Risk Prediction
Zhang, J.; Zhan, J.; Jin, J.; Ma, C.; Zhao, R.; Connell, J. O.; Jiang, Y.; 23andMe Research Team, ; Koelsch, B. L.; Zhang, H.; Chatterjee, N.
10.1101/2023.03.15.532652 — genetics — Posted on 2023-03-16
2250 Comparative phylogeography reveals widespread cryptic diversity driven by ecology in Panamanian birds
McLaughlin, J. F.; Aguilar, C.; Bernstein, J. M.; Navia-Gine, W. G.; Cueto-Aparicio, L. E.; Alarcon, A. C.; Alarcon, B. D.; Collier, R.; Takyar, A.; Vong, S. J.; Lopez-Chong, O. G.; Driver, R.; Loaiza, J. R.; De Leon, L. F.; Saltonstall, K.; Lipshutz, S. E.; Arcila, D.; Brock, K. M.; Miller, M. J.
10.1101/2023.03.15.530646 — evolutionary biology — Posted on 2023-03-16
2252 Loss Of Chromodomain of Male-Specific Lethal 3 (MSL3) Does Not Affect Spermatogenesis In Rodents
Mitchell, T.; Lin, J. M.; James, J. R.; Hicks, S. M.; McCarthy, A.; Rangan, P.; Forni, P. E.
10.1101/2023.03.16.532933 — developmental biology — Posted on 2023-03-16
2253 Cross-species single-cell comparison of systemic and cardiac inflammatory responses after cardiac injury
Cortada, E.; Yao, J.; Xia, Y.; Dundar, F.; Zumbo, P.; Yang, B.; Rubio-Navarro, A.; Perder, B.; Qiu, M.; Pettinato, A. M.; Homan, E. A.; Stoll, L.; Betel, D.; Cao, J.; Lo, J.
10.1101/2023.03.15.532865 — cell biology — Posted on 2023-03-16
2254 A protein hydroxylase couples epithelial membrane biology to nucleolar ribosome biogenesis
Hendrix, E.; Andrijes, R.; Boora, U.; Kaur, A.; Bundred, J. R.; Zayer, A.; Heilig, R.; Westrip, C. A. E.; Fletcher, S. F.; Eaton, C. D.; Kennedy, T. J.; Piasecka, S.; Fischer, R.; Smerdon, S. J.; Coleman, M. L.
10.1101/2023.03.15.532818 — cell biology — Posted on 2023-03-16
2255 Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis
Watanuki, S.; Kobayashi, H.; Sugiura, Y.; Yamamoto, M.; Karigane, D.; Shiroshita, K.; Sorimachi, Y.; Koide, S.; Oshima, M.; Nishiyama, A.; Murakami, K.; Miho, H.; Tamaki, S.; Yamamoto, T.; Yabushita, T.; Tanaka, Y.; Honda, H.; Okamoto, S.; Goda, N.; Tamura, T.; Nakamura-Ishizu, A.; Suematsu, M.; Iwama, A.; Suda, T.; Takubo, K.
10.1101/2023.03.16.532898 — cell biology — Posted on 2023-03-16
2256 MFN2-dependent recruitment of ATAT1 coordinates mitochondria motility with alpha-tubulin acetylation and is disrupted in CMT2A
Kumar, A.; Larrea, D.; Pero, M. E.; Infante, P.; Conenna, M.; Shin, G. J.-e.; Grueber, W. B.; Di Marcotullio, L.; Area-Gomez, E.; Bartolini, F.
10.1101/2023.03.15.532838 — cell biology — Posted on 2023-03-16
2257 Length-dependent translation efficiency of ER-destined proteins
Sahinbegovic, H.; Vdovin, A.; Snaurova, R.; Durech, M.; Nezval, J.; Sobotka, J.; Hajek, R.; Jelinek, T.; Simicek, M.
10.1101/2023.03.16.532890 — molecular biology — Posted on 2023-03-16
2258 Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types
McCormack, C. P.; Yan, A. W. C.; Brown, J. C.; Sukhova, K.; Peacock, T. P.; Barclay, W. S.; Dorigatti, I.
10.1101/2023.03.15.529513 — microbiology — Posted on 2023-03-16
2259 The highly conserved stem-loop II motif is dispensable for SARS-CoV-2
Jiang, H.; Joshi, A.; Gan, T.; Janowski, A. B.; Fujii, C.; Bricker, T. L.; Darling, T.; Harastani, H. H.; Seehra, K.; Chen, H.; Tahan, S.; Jung, A.; Febles, B.; Blatter, J. A.; Handley, S.; Parikh, B. A.; Wang, D.; Boon, A. C.
10.1101/2023.03.15.532878 — microbiology — Posted on 2023-03-16
2261 Tetravalent SARS-CoV-2 S1 Subunit Protein Vaccination Elicits Robust Humoral and Cellular Immune Responses in SIV-Infected Rhesus Macaque Controllers
Khan, M. S.; Kim, E.; Le Hingrat, Q.; Kleinman, A.; Ferrari, A.; Sammartino, J. C.; Percivalle, E.; Xu, C.; Huang, S.; Kenniston, T. W.; Cassaniti, I.; Baldanti, F.; Pandrea, I.; Gambotto, A.; Apetrei, C.
10.1101/2023.03.15.532808 — immunology — Posted on 2023-03-16
2263 Bipartite invariance in mouse primary visual cortex
Ding, Z.; Tran, D. T.; Ponder, K.; Cobos, E.; Ding, Z.; Fahey, P. G.; Wang, E.; Muhammad, T.; Fu, J.; Cadena, S. A.; Papadopoulos, S.; Patel, S.; Franke, K.; Reimer, J.; Sinz, F. H.; Ecker, A. S.; Pitkow, X.; Tolias, A. S.
10.1101/2023.03.15.532836 — neuroscience — Posted on 2023-03-16
2265 An alphacoronavirus polymerase structure reveals conserved co-factor functions
Anderson, T. K.; Hoferle, P. J.; Lee, K. W.; Coon, J. J.; Kirchdoerfer, R. N.
10.1101/2023.03.15.532841 — biochemistry — Posted on 2023-03-16
2267 Single-molecule acceptor rise time (smART) FRET for nanoscale distance sensitivity
Guo, J.; Chen, X.; Manna, P.; Lin, X.; Scott, M. N.; Chen, W. J.; Hoffman, M.; Zhang, B.; Schlau-Cohen, G. S.
10.1101/2023.03.15.532809 — biophysics — Posted on 2023-03-16
2268 Engineering Particle-based Materials for Vasculogenesis
Claxton, N. L.; Luse, M. A.; Isakson, B. E.; Highley, C. B.
10.1101/2023.03.15.532817 — bioengineering — Posted on 2023-03-16
2271 Structural insights into TRPV4-Rho GTPase signaling complex function and disease
Kwon, D. H.; Zhang, F.; McCray, B. A.; Kumar, M.; Sullivan, J.; Sumner, C.; Lee, S.-Y.
10.1101/2023.03.15.532784 — biophysics — Posted on 2023-03-16
2272 Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2
Suo, Y.; Wright, N. J.; Guterres, H.; Fedor, J. G.; Butay, K. J.; Borgnia, M. J.; Im, W.; Lee, S.-Y.
10.1101/2023.03.15.532610 — biophysics — Posted on 2023-03-16
2273 Tropomyosin 1-I/C co-ordinates kinesin-1 and dynein motors during oskar mRNA transport
Heber, S.; McClintock, M. A.; Simon, B.; Hennig, J.; Bullock, S. L.; Ephrussi, A.
10.1101/2022.10.26.513919 — biochemistry — Posted on 2023-03-16
2275 Human postmortem studies reveal tissue-specific differences amongst TB-patient groups
Ahimbisibwe, G.; Nakibuule, M.; Ssejjoba, M.; Oyamo, D.; Mulwana, R.; Nabulime, J.; Babirye, F.; Kizito, A.; Lekuya, H.; Adakun, S.; Kyazze, A.; Lukande, R.; Baluku, J.; Biraro, I.; Cose, S.
10.1101/2023.03.14.532701 — immunology — Posted on 2023-03-16
2277 Saccadic omission revisited: What saccade-induced smear looks like
Schweitzer, R.; Doering, M. S.; Seel, T.; Raisch, J.; Rolfs, M.
10.1101/2023.03.15.532538 — neuroscience — Posted on 2023-03-16
2279 Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity
Houlahan, K. E.; Khan, A.; Greenwald, N. F.; West, R. B.; Angelo, M.; Curtis, C.
10.1101/2023.03.15.532870 — cancer biology — Posted on 2023-03-16
2286 Division of labor promotes the entrenchment of multicellularity
Conlin, P. L.; Goldsby, H. J.; Libby, E.; Skocelas, K. G.; Ratcliff, W. C.; Ofria, C.; Kerr, B.
10.1101/2023.03.15.532780 — evolutionary biology — Posted on 2023-03-16
2287 An EOMES induced epigenetic deflection initiates lineage commitment at mammalian gastrulation
Schröder, C. M.; Zissel, L.; Mersiowsky, S.-L.; Tekman, M.; Probst, S.; Schüle, K. M.; Preissl, S.; Schilling, O.; Timmers, H. T. M.; Arnold, S. J.
10.1101/2023.03.15.532746 — developmental biology — Posted on 2023-03-16
2289 Spiny but photogenic: amateur sightings complement herbarium specimens to reveal the bioregions of cacti
Calvente, A.; Silva, A. P.; Edler, D.; Carvalho, F. A.; Fantinati, M. R.; Zizka, A.; Antonelli, A.
10.1101/2023.03.15.532806 — plant biology — Posted on 2023-03-16
2292 Hyperspectral Oblique Plane Microscopy
Guo, K.; Kalyviotis, K.; Pantazis, P.; Rowlands, C. J.
10.1101/2023.03.15.532804 — bioengineering — Posted on 2023-03-16
2294 Delineation of two multi-invasion-induced rearrangement pathways that differently affect genome stability
Reitz, D.; Djeghmoum, Y.; Watson, R. A.; Rajput, P.; Argueso, J. L.; Heyer, W.-D.; Piazza, A.
10.1101/2023.03.15.532751 — genetics — Posted on 2023-03-16
2295 An evolutionary epigenetic clock in plants
Yao, N.; Zhang, Z.; Yu, L.; Hazarika, R.; Yu, C.; Jang, H.; Smith, L. M.; Ton, J.; Liu, L.; Stachowicz, J.; Reusch, T. B. H.; Schmitz, R. J.; Johannes, F.
10.1101/2023.03.15.532766 — evolutionary biology — Posted on 2023-03-16
2297 Cerebellar Activation Bidirectionally Regulates Nucleus Accumbens Core and Medial Shell
D'Ambra, A. F.; Vlasov, K.; Jung, S. J.; Ganesan, S.; Antzoulatos, E. G.; Fioravante, D.
10.1101/2020.09.28.283952 — neuroscience — Posted on 2023-03-16
2300 A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
Garnish, S. E.; Martin, K. R.; Kauppi, M.; Jackson, V.; Ambrose, R.; Eng, V. V.; Chiou, S.; Meng, Y.; Frank, D.; Tovey Crutchfield, E. C.; Patel, K. M.; Jacobsen, A.; Atkin-Smith, G.; Di Rago, L.; Doerflinger, M.; Horne, C. R.; Hall, C.; Young, S. N.; Athanasopoulos, V.; Vinuesa, C. G.; Lawlor, K. E.; Wicks, I.; Ebert, G.; Ng, A. P.; Slade, C. A.; Pearson, J. S.; Samson, A. L.; Silke, J.; Murphy, J. M.; Hildebrand, J.
10.1101/2022.09.08.507056 — immunology — Posted on 2023-03-16
2301 Neural signatures of declarative memory cueing using odors during sleep
Sanchez-Corzo, A.; Baum, D. M.; Irani, M.; Hinrichs, S.; Reisenegger, R.; Whitaker, G. A.; Born, J.; Klinzing, J. G.; Sitaram, R.
10.1101/2023.02.10.527339 — neuroscience — Posted on 2023-03-16
2302 Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes
Becker, M. W.; Peters, L. D.; Myint, T.; Smurlick, D.; Powell, A.; Brusko, T. M.; Phelps, E. A.
10.1101/2022.11.23.517693 — bioengineering — Posted on 2023-03-16
2303 Bold but not innovative in an urban exploiter, the red fox (Vulpes vulpes)
Morton, B.; Gartner, M.; Norrie, E.-M.; Haddou, Y.; Soulsbury, C. D.; Adaway, K.
10.1101/2022.11.04.515174 — animal behavior and cognition — Posted on 2023-03-16
2304 Differentiation trajectories of the Hydra nervous system reveal transcriptional regulators of neuronal fate
Primack, A. S.; Cazet, J. F.; Morris Little, H.; Mühlbauer, S.; Cox, B. D.; David, C. N.; Farrell, J. A.; Juliano, C.
10.1101/2023.03.15.531610 — developmental biology — Posted on 2023-03-16
2305 Intense light unleashes male-male courtship behaviorin wild-type Drosophila
Ueda, A.; Berg, A.; Khan, T.; Ruzicka, M.; Li, S.; Cramer, E.; Iyengar, A.; Wu, C.-F.
10.1101/2022.07.12.499756 — neuroscience — Posted on 2023-03-16
2307 Taxonomic distribution of metabolic functions underpin nutrient cycling in Trichodesmium consortia
Koedooder, C.; Zhang, F.; Wang, S.; Haley, S. T.; Tolic, N.; Nicora, C. D.; Basu, S.; Gledhill, M.; Boiteau, R.; Dyhrman, S.; Rubin-Blum, M.; Shaked, Y.
10.1101/2023.03.15.532517 — microbiology — Posted on 2023-03-16
2309 Hypothalamic thyroid hormone deficiency underlies reversible anorexia in a mammalian hibernator
Mohr, S. M.; Pra, R. D.; Platt, M. P.; Feketa, V. V.; Shanabrough, M.; Varela, L.; Kristant, A.; Cao, H.; Merriman, D. K.; Horvath, T. L.; Bagriantsev, S. N.; Gracheva, E. O.
10.1101/2023.03.15.532843 — physiology — Posted on 2023-03-16
2312 MRE11A: a novel negative regulator of human DNA mismatch repair
Liu, D.; Du, D.; Yang, Y.; Chen, L.; Guan, X.; Rasmussen, L.; Wang, G.
10.1101/2023.03.15.532782 — molecular biology — Posted on 2023-03-15
2314 Changes in Environmental Stress over COVID-19 Pandemic Likely Contributed to Failure to Replicate Adiposity Phenotype Associated with Krtcap3
Szalanczy, A. M.; Giorgio, G.; Goff, E.; Seshie, O.; Grzybowski, M.; Klotz, J.; Geurts, A. M.; Redei, E. E.; Solberg Woods, L. C.
10.1101/2023.03.15.532439 — molecular biology — Posted on 2023-03-15
2316 In vitro and in vivo combination of lytic phages and octapeptin OPX10053 against B-lactamase-producing clinical isolates of Klebsiella pneumoniae
Pacios, O.; Blasco, L.; Bleriot, I.; Fernandez-Garcia, L.; Lopez-Diaz, M.; Ortiz-Cartagena, C.; Barrio-Pujante, A.; Fernandez-Cuenca, F.; Aracil, B.; Oteo-Iglesias, J.; Hansford, K. A.; Tomas, M.
10.1101/2023.03.15.532768 — microbiology — Posted on 2023-03-15
2317 Viruses encode tRNA and anti-retron to evade bacterial immunity
Azam, A. H.; Chihara, K.; Kondo, K.; Nakamura, T.; Ojima, S.; Tamura, A.; Yamashita, W.; Cui, L.; Takahashi, Y.; Watashi, K.; Kiga, K.
10.1101/2023.03.15.532788 — microbiology — Posted on 2023-03-15
2319 Structural insights into TRPV4-Rho GTPase signaling complex function and disease
Lee, S.-Y.; Kwon, D. H.; Zhang, F.; Sumner, C.; McCray, B. A.; Sullivan, J.; Kumar, M.
10.1101/2023.03.15.532784 — biophysics — Posted on 2023-03-15
2320 Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction
Twizere, J.-C.; Maseko, S.; Brammerloo, Y.; Van.Molle, I.; Sogues Castrejon, A.; Martin, C.; Gorgulla, C.; Olivet, J.; Blavier, J.; Ntombela, T.; Frank, D.; Arthanari, H.; Remaut, H.; Salehi-Ashtiani, K.; Ballet, S.; Volkov, O.
10.1101/2023.03.15.532789 — biochemistry — Posted on 2023-03-15
2321 Cysteine: an ancestral Cu binding ligand in green algae?
Strenkert, D.; Schmollinger, S.; Hu, Y.; Hofmann, C.; Holbrook, K.; Liu, H. W.; Purvine, S. O.; Nicora, C. D.; Chen, S.; Lipton, M. S.; Northen, T. R.; Clemens, S.; Merchant, S. S.
10.1101/2023.03.15.532757 — biochemistry — Posted on 2023-03-15
2322 Point mutations in IMPDH2 which cause early-onset neurodevelopmental disorders disrupt enzyme regulation and filament structure
O'Neill, A. G.; Burrell, A. L.; Zech, M.; Elpeleg, O.; Harel, T.; Edvardson, S.; Shaked, H. M.; Rippert, A. L.; Nomakuchi, T.; Izumi, K.; Kollman, J. M.
10.1101/2023.03.15.532669 — biochemistry — Posted on 2023-03-15
2323 Insufficient evidence for natural selection associated with the Black Death
Barton, A. R.; Santander, C. G.; Skoglund, P.; Moltke, I.; Reich, D.; Mathieson, I.
10.1101/2023.03.14.532615 — genomics — Posted on 2023-03-15
2324 Hox genes modulate physical forces to differentially shape small and large intestinal epithelia
Gill, H. K.; Yin, S.; Nerurkar, N. L.; Lawlor, J. C.; Huycke, T. R.; Mahadevan, L.; Tabin, C. J.
10.1101/2023.03.15.532602 — developmental biology — Posted on 2023-03-15
2328 Predatory Bacteria can Reduce Pseudomonas aeruginosa Induced Corneal Perforation and Proliferation in a Rabbit Keratitis Model
Romanowski, E. G.; Stella, N. A.; Brazile, B. L.; Lathrop, K. L.; Franks, J. M.; Sigal, I. A.; Kim, T.; Elsayed, M.; Kadouri, D. E.; Shanks, R. M. Q.
10.1101/2023.03.15.532777 — microbiology — Posted on 2023-03-15
2329 Distribution of blaCTX-M-gene variants in E. coli from different origins in Ecuador
Valenzuela, X.; Hedman, H.; Villagomez, A.; Cardenas, P. A.; Eisenberg, J.; Levy, K.; Zhang, L.; Trueba, G.
10.1101/2023.03.15.532797 — microbiology — Posted on 2023-03-15
2332 Duplicate transcription factors GT1 and VRS1 regulate branching and fertile flower number in maize and Brachypodium distachyon
Gallagher, J. P.; Man, J.; Chiaramida, A.; Rozza, I.; Patterson, E. L.; Powell, M. M.; Schrager-Lavelle, A.; Multani, D. S.; Meeley, R. B.; Bartlett, M. E.
10.1101/2023.03.15.532786 — plant biology — Posted on 2023-03-15
2335 Global disinhibition and corticospinal plasticity for drastic recovery after spinal cord injury
Yamaguchi, R.; Ueno, S.; Kawasaki, T.; Chao, Z.; Mitsuhashi, M.; Isa, K.; Takei, T.; Kobayashi, K.; Takahashi, J.; Onoe, H.; Isa, T.
10.1101/2023.03.15.532773 — neuroscience — Posted on 2023-03-15
2338 A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes
Fernandez-Moncada, I.; B. Fundazuri, U.; Lavanco, G.; Bollmohr, N.; Hachaguer, P.; Dalla Tor, T.; Mountadem, S.; Serrat, R.; Bellocchio, L.; Cannich, A.; Nasu, Y.; Campbell, R. E.; Drago, F.; Bouzier-Sore, A.-K.; Pellerin, L.; Bolanos, J. P.; Bonvento, G.; Barros, L. F.; Oliet, S. H. R.; Panatier, A.; Marsicano, G.
10.1101/2023.03.15.532748 — neuroscience — Posted on 2023-03-15
2340 Neural and behavioral correlates of edible cannabis-induced poisoning: characterizing a novel preclinical model
Amissah, R. Q.; Kayir, H.; Talhat, M. A.; Hassan, A.; Gu, Y.; Johnson, R.; Urban, K.; Khokhar, J. Y.
10.1101/2023.03.15.532815 — neuroscience — Posted on 2023-03-15
2342 BioConvert: a comprehensive format converter for life sciences
Caro, H.; Dollin, S.; Biton, A.; Brancotte, B.; Desvillechabrol, D.; Dufresne, Y.; Li, B.; Kornobis, E.; Lemoine, F.; Maillet, N.; PERRIN, A.; Traut, N.; Neron, B.; Cokelaer, T.
10.1101/2023.03.13.532455 — bioinformatics — Posted on 2023-03-15
2345 Antimicrobial peptides modulate lung injury by altering the intestinal microbiota
Abdelgawad, A.; Nicola, T.; Martin, I.; Halloran, B. A.; Tanaka, K.; Adegboye, C. Y.; Jain, P.; Ren, C.; Lal, C. V.; Ambalavanan, N.; O'Connell, A. E.; Jilling, T.; Willis, K. A.
10.1101/2023.03.14.529700 — microbiology — Posted on 2023-03-15
2348 Epithelial galectin-3 induces mitochondrial complex inhibition and cell cycle arrest of CD8+ T Cells in severe/critical ill COVID-19
Wang, Y.; Yang, C.; Wang, Z.; Wang, Y.; Yan, Q.; Feng, Y.; Liu, Y.; Zhang, X.; Zhao, J.; Huang, J.; Zhou, J.
10.1101/2023.03.14.532609 — immunology — Posted on 2023-03-15
2349 The 3D Structural Architecture of the Human Hand Area is Non-Topographic
Doehler, J.; Northall, A.; Liu, P.; Fracasso, A.; Chrysidou, A.; Speck, O.; Lohmann, G.; Wolbers, T.; Kuehn, E.
10.1101/2022.07.28.501903 — neuroscience — Posted on 2023-03-15
2351 State-dependent GABAergic regulation of striatal spiny projection neuron excitability
Day, M.; Belal, M.; Surmeier, C.; Melendez-Zaidi, A.; Tkatch, T.; Clarke, V. R. J.; Surmeier, D. J.
10.1101/2023.03.14.532627 — neuroscience — Posted on 2023-03-15
2353 An ancestral vaccine induces anti-Omicron antibodies by hypermutation
Park, S.; Choi, J.; Lee, Y.; Noh, J.; Kim, N.; Lee, J.; Cho, G.; Kim, S.; Yoo, D. K.; Kang, C. K.; Choe, P. G.; Kim, N. J.; Park, W. B.; Kim, S.; Oh, M.-d.; Kwon, S.; Chung, J.
10.1101/2023.03.15.532728 — bioengineering — Posted on 2023-03-15
2360 What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds
Durairaj, J.; Waterhouse, A.; Mets, T.; Brodiazhenko, T.; Abdullah, M.; Studer, G.; Akdel, M.; Andreeva, A.; Bateman, A.; Hauryliuk, V.; Tenson, T.; Schwede, T.; Pereira, J.
10.1101/2023.03.14.532539 — bioinformatics — Posted on 2023-03-15
2362 Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice
Bashkirova, E.; Klimpert, N.; Pourmorady, A.; Monahan, K.; Campbell, C.; Osinski, J.; Tan, L.; Schieren, I.; Stecky, R.; Barnea, G.; Xie, X. S.; Abdus-Saboor, I.; Shykind, B.; Marlin, B. J.; Gronostajski, R.; Fleischmann, A.; Lomvardas, S.
10.1101/2023.03.15.532726 — genomics — Posted on 2023-03-15
2363 Defining ancestry, heritability and plasticity of cellular phenotypes in somatic evolution
Schiffman, J. S.; D'Avino, A. R.; Prieto, T.; Pang, Y.; Fan, Y.; Rajagopalan, S.; Potenski, C.; Hara, T.; Suva, M. L.; Gawad, C.; Landau, D. A.
10.1101/2022.12.28.522128 — evolutionary biology — Posted on 2023-03-15
2364 Live-trapping of rodents in urban green spaces across Los Angeles
Friscia, A. R.; Helman, S.; Maloney, M.; Molina-Echavarria, A. K.; Nugen, S.; Punjabi, N.; Tweedt, I.; Lynch, J.
10.1101/2023.03.13.531394 — ecology — Posted on 2023-03-15
2367 Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment
Villa, M.; Sanin, D. E.; Apostolova, P.; Corrado, M.; Kabat, A. M.; Cristinzio, C.; Regina, A.; Carrizo, G.; Rana, N.; Stanczak, M. A.; Baixauli, F.; Grzes, K. M.; Cupovic, J.; Solagna, F.; Hackl, A.; Globig, A.-M.; Haessler, F.; Puleston, D. J.; Kelly, B.; Cabezas-Wallscheid, N.; Hasselblatt, P.; Bengsch, B.; Zeiser, R.; Sagar, ; Buescher, J. M.; Pearce, E. J.; Pearce, E. L.
10.1101/2023.03.13.532431 — immunology — Posted on 2023-03-15
2369 Saccadic omission revisited: What saccade-induced smear looks like
Schweitzer, R.; Doering, M. S.; Seel, T.; Raisch, J.; Rolfs, M.
10.1101/2023.03.15.532538 — neuroscience — Posted on 2023-03-15
2370 Inhibitory input directs astrocyte morphogenesis through glial GABABR
Cheng, Y.-T.; Luna-Figueroa, E.; Woo, J.; Chen, H.-C.; Lee, Z.-F.; Harmanci, A. S.; Deneen, B.
10.1101/2023.03.14.532493 — neuroscience — Posted on 2023-03-15
2371 Immunogenetic metabolomics revealed key enzymes that modulate CAR-T metabolism and function
Renauer, P. A.; Park, J. J.; Bai, M.; Acosta, A.; Lee, W.-H.; Lin, G. H.; Zhang, Y.; Dai, X.; Wang, G.; Errami, Y.; Wu, T.; Clark, P.; Ye, L.; Yang, Q.; Chen, S.
10.1101/2023.03.14.532663 — cancer biology — Posted on 2023-03-15
2373 Imaging angiogenesis in an intracerebrally induced model of brain macrometastasis using αvβ3-targeted iron oxide microparticles
Buck, J.; Perez-Balderas, F.; Zarghami, N.; Johanssen, V. A.; Khrapitchev, A. A.; Larkin, J. R.; Sibson, N. R.
10.1101/2023.03.14.532679 — cancer biology — Posted on 2023-03-15
2375 Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies
Cosgun, K. N.; Jumaa, H.; Robinson, M. E.; Liang, X.; Xiao, G.; Chan, L. N.; Lee, J.; Kume, K.; Leveille, E.; Fonseca-Arce, D.; Khanduja, D.; Ng, H. L.; Feldhahn, N.; Song, J.; Chan, W. C.; Chen, J.; Taketo, M. M.; Kothari, S.; Davids, M. S.; Schjerven, H.; Jellusova, J.; Mueschen, M.
10.1101/2023.03.13.532152 — cancer biology — Posted on 2023-03-15
2376 Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting the oxysterol-binding protein OSBP
Cigler, M.; Imrichova, H.; Frommelt, F.; Depta, L.; Rukavina, A.; Kagiou, C.; Hannich, J. T.; Mayor-Ruiz, C.; Superti-Furga, G.; Sievers, S.; Laraia, L.; Waldmann, H.; Winter, G. E.
10.1101/2023.03.15.532743 — pharmacology and toxicology — Posted on 2023-03-15
2378 CETP inhibitor evacetrapib enters mouse brain tissue
Phenix, J.; Cote, J.; Dieme, D.; Recinto, S. J.; Oestereich, F.; Efrem, S.; Haddad, S.; Bouchard, M.; Munter, L. M.
10.1101/2023.02.21.529381 — pharmacology and toxicology — Posted on 2023-03-15
2380 A mathematical model of the disruption of glucose homeostasis in cancer patients
Salentine, N.; Doria, J.; Nguyen, C.; Pinter, G. A.; Wang, S. E.; Hinow, P.
10.1101/2023.03.15.532725 — cancer biology — Posted on 2023-03-15
2382 Platelet Activating Factor Activity Modulates Hyperoxic Neonatal Lung Injury Severity
Yee, A.; Kandasamy, J.; Ambalavanan, N.; Ren, C.; Halloran, B.; Olave, N.; Nicola, T.; Jilling, T.
10.1101/2023.03.14.532697 — pathology — Posted on 2023-03-15
2390 Modelling collagen fibril self-assembly from extracellular medium in embryonic tendon
Revell, C. K.; Herrera, J. A.; Lawless, C.; Lu, Y.; Kadler, K. E.; Chang, J.; Jensen, O. E.
10.1101/2023.03.13.532430 — biophysics — Posted on 2023-03-15
2391 Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome
Venkatraman, K.; Lee, C. T.; Garcia, G. C.; Mahapatra, A.; Perkins, G.; Kim, K.-Y.; Pasolli, H. A.; Phan, S.; Lippincott-Schwartz, J.; Ellisman, M.; Rangamani, P.; Budin, I.
10.1101/2023.03.13.532310 — biophysics — Posted on 2023-03-15
2393 BioConvert: a comprehensive format converter for life sciences
Caro, H.; Dollin, S.; Brancotte, B.; Desvillechabrol, D.; Dufresne, Y.; Li, B.; Biton, A.; Kornobis, E.; Lemoine, F.; Maillet, N.; PERRIN, A.; Traut, N.; Neron, B.; Cokelaer, T.
10.1101/2023.03.13.532455 — bioinformatics — Posted on 2023-03-15
2399 Library size confounds biology in spatial transcriptomics data
Bhuva, D. D.; Tan, C. W.; Marceaux, C.; Chen, J.; Kharbanda, M.; Jin, X.; Liu, N.; Feher, K.; Putri, G.; Asselin-Labat, M.-L.; Phipson, B.; Davis, M. J.
10.1101/2023.03.15.532733 — bioinformatics — Posted on 2023-03-15
2400 Improved integration of single cell transcriptome data demonstrated on heart failure in mice and men
Jurado, M. R.; Tombor, L. S.; Arsalan, M.; Holubec, T.; Emrich, F.; Walther, T.; Zeiher, A. M.; Schulz, M. H.; Dimmeler, S.; John, D.
10.1101/2023.03.15.532742 — bioinformatics — Posted on 2023-03-15
2404 Therapeutic immune cell engineering with an mRNA : AAV-Sleeping Beauty composite system
Ye, L.; Lam, S. Z.; Yang, L.; Suzuki, K.; Zou, Y.; Lin, Q.; Zhang, Y.; Clark, P.; Peng, L.; Chen, S.
10.1101/2023.03.14.532651 — bioengineering — Posted on 2023-03-15
2406 Single-shot 3D photoacoustic tomography using a single-element detector for ultrafast imaging of hemodynamics
Zhang, Y.; Hu, P.; Li, L.; Cao, R.; Khadria, A.; Maslov, K.; Tong, X.; Zeng, Y.; Jiang, L.; Zhou, Q.; Wang, L.
10.1101/2023.03.14.532661 — bioengineering — Posted on 2023-03-15
2407 Constitutively synergistic multiagent drug formulations targeting MERTK, FLT3, and BCL-2 for treatment of AML
Kelvin, J. M.; Jain, J.; Thapa, A.; Qui, M.; Birnbaum, L. A.; Moore, S. G.; Zecca, H.; Summers, R. J.; Costanza, E.; Uricoli, B.; Wang, X.; Jui, N. T.; Fu, H.; Du, Y.; DeRyckere, D.; Graham, D. K.; Dreaden, E. C.
10.1101/2023.03.13.531236 — bioengineering — Posted on 2023-03-15
2408 Urine proteomic characterization of active and recovered COVID-19 patients
Sun, J.; Wei, J.; Yu, H.; Sun, H.; Liu, X.; Zhang, Y.; Shao, C.; Sun, W.; Zhang, J.; Gao, Y.
10.1101/2023.03.12.532269 — biochemistry — Posted on 2023-03-15
2409 Intracellular biotransformation and disposal mechanisms of magnetosomes in macrophages and cancer cells
Gandarias, L.; G. Gubieda, A.; Gorni, G.; Mathon, O.; Olivi, L.; Abad-Diaz-de-Cerio, A.; Fdez-Gubieda, M. L.; Muela, A.; Garcia-Prieto, A.
10.1101/2023.03.15.532722 — biochemistry — Posted on 2023-03-15
2411 Endophyte genomes support greater metabolic gene cluster diversity compared with non-endophytes in Trichoderma
Scott, K.; Konkel, Z.; Gluck-Thaler, E.; David, G. E. V.; Simmt, C. F.; Grootmyers, D.; Chaverri, P.; Slot, J.
10.1101/2023.03.14.532605 — genomics — Posted on 2023-03-15
2412 One Health Assessment of an Urban Temporary Settlement Reveals Gut Microbiome Serving as Antimicrobial Resistance Gene Reservoir
Napit, R.; Gurung, A.; Poudel, A.; Manandhar, P.; Chaudhary, A. B.; Sharma, A. N.; Raut, S.; Pradhan, S. M.; Joshi, J.; Poyet, M.; Groussin, M.; Rajbhandari, R. M.; Karmacharya, D.
10.1101/2023.03.15.532708 — genomics — Posted on 2023-03-15
2413 Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data
Dai, R.; Chu, T.; Zhang, M.; Wang, X.; Jourdon, A.; Wu, F.; Mariani, J.; Vaccarino, F. M.; Lee, D.; Fullard, J. F.; Hoffman, G. E.; Roussos, P.; Wang, Y.; Wang, X.; Pinto, D.; Wang, S.; Zhang, C.; Chen, C.; LIU, C.
10.1101/2023.03.13.532468 — genomics — Posted on 2023-03-15
2414 Genome-wide methylome stability and parental effects in the worldwide distributed Lombardy poplar
Vanden Broeck, A.; Meese, T.; Verschelde, P.; Cox, K.; Heinze, B.; Deforce, D.; De Meester, E.; Van Nieuwerburgh, F.
10.1101/2023.03.14.532102 — genomics — Posted on 2023-03-15
2415 Cis-regulatory control of transcriptional timing and noise in response to estrogen
GInley-Hidinger, M.; Abewe, H.; Osborne, K.; Mortenson, K. L.; Richey, A.; Wissink, E. M.; Lis, J.; Zhang, X.; Gertz, J.
10.1101/2023.03.14.532457 — genomics — Posted on 2023-03-15
2417 Technical and biological sources of unreliability of Infinium type II probes of the Illumina MethylationEPIC BeadChip microarray
Nazarenko, T.; Vavourakis, C. D.; Jones, A.; Evans, I.; Watson, A.; Brandt, K.; Carter, C.; Zaikin, A.; Herzog, C.; Widschwendter, M.
10.1101/2023.03.14.532595 — genomics — Posted on 2023-03-15
2422 Molecular signature of domestication in the arboviral vector Aedes aegypti
Lozada-Chavez, A. N.; Lozada-Chavez, I.; Alfano, N.; Palatini, U.; Sogliani, D.; Elfekih, S.; Degefa, T.; Sharakhova, M. V.; Badolo, A.; Patchara, S.; Casas-Martinez, M.; Carlos, B.; Carballar-Lejarazu, R.; Lambrechts, L.; Souza-Neto, J.; Bonizzoni, M.
10.1101/2023.03.13.532092 — evolutionary biology — Posted on 2023-03-15
2426 Transgenerational virulence: Maternal pathogen exposure reduces offspring fitness
McIntire, K. M.; Dziuba, M. K.; Haywood, E. B.; Robertson, M. L.; Vaandrager, M.; Baird, E.; Corcoran, F.; Cortez, M. H.; Duffy, M. A.
10.1101/2023.03.14.532659 — ecology — Posted on 2023-03-15
2429 Detecting differences in Size Spectra
Pomeranz, J. P.; Junker, J. R.; Gjoni, V.; Wesner, J. S.
10.1101/2023.03.14.532592 — ecology — Posted on 2023-03-15
2431 CellDeathPred: A Deep Learning framework for Ferroptosis and Apoptosis prediction based on cell painting
Schorpp, K.; Bessadok, A.; Biibosunov, A.; Rothenaigner, I.; Strasser, S.; Peng, T.; Hadian, K.
10.1101/2023.03.14.532633 — cell biology — Posted on 2023-03-15
2432 The bromodomain inhibitor JQ1 is a molecular glue targeting centromeres
Corless, S.; Singh, N. P.; Benabdallah, N.; Boehm, J.; Simon, A. M.; Dolejs, V.; Anders, S.; Banito, A.; Erhardt, S.
10.1101/2023.03.15.532673 — molecular biology — Posted on 2023-03-15
2433 Antimicrobial peptides modulate pulmonary inflammation by altering the intestinal microbiota
Abdelgawad, A.; Nicola, T.; Martin, I.; Halloran, B. A.; Tanaka, K.; Adegboye, C. Y.; Jain, P.; Ren, C.; Lal, C. V.; Ambalavanan, N.; O'Connell, A. E.; Jilling, T.; Willis, K. A.
10.1101/2023.03.14.529700 — microbiology — Posted on 2023-03-15
2435 Predicting metabolic response to dietary intervention using deep learning
Wang, T.; Holscher, H. D.; Maslov, S.; Hu, F. B.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2023.03.14.532589 — microbiology — Posted on 2023-03-15
2438 First Molecular Detection of Influenza D virus in Cattle from Commercial farm in Nigeria, Sub-Saharan Africa
Anjorin, A.-A. A.; Moronkeji, G. O.; Temenu, G. O.; Maiyegun, O. A.; Fakorede, C. O.; Ajoseh, S. O.; Salami, W. O.; Abegunrin, R. O.; Amisu, K. O.; Akinyemi, K. O.
10.1101/2023.03.15.532744 — microbiology — Posted on 2023-03-15
2439 Role of the Escherichia coli ubiquinone-synthesizing UbiUVT pathway in adaptation to changing respiratory conditions
Arias-Cartin, R.; Kazemzadeh Ferizhendi, K.; Sechet, E.; Pelosi, L.; Loeuillet, C.; Pierrel, F.; Barras, F.; Bouveret, E.
10.1101/2023.03.15.532739 — microbiology — Posted on 2023-03-15
2442 Age-dependent roles of cardiac remodeling in sepsis defense and pathogenesis
Sanchez, K. K.; McCarville, J. L.; Stengel, S. J.; Snyder, J. M.; Williams, A. E.; Ayres, J. S.
10.1101/2023.03.14.532695 — immunology — Posted on 2023-03-15
2443 CTLA-4 tail fusion enhances CAR-T anti-tumor immunity
Zhou, X.; Cao, H.; Fang, S.-Y.; Chow, R. D.; Tang, K.; Majety, M.; Bai, M.; Dong, M. B.; Renauer, P. A.; Shang, X.; Suzuki, K.; Levchenko, A.; Chen, S.
10.1101/2023.03.14.532655 — immunology — Posted on 2023-03-15
2447 The impact of paediatric epilepsy and co-occurring neurodevelopmental disorders on functional brain networks in wake and sleep
Junges, L.; Galvis, D.; Winsor, A.; Treadwell, G.; Richards, C.; Seri, S.; Johnson, S.; Terry, J. R.; Bagshaw, A. P.
10.1101/2023.03.15.530959 — neuroscience — Posted on 2023-03-15
2449 Uneven terrain versus dual-task walking: differential challenges imposed on walking behavior in older adults are predicted by cognitive and sensorimotor function
Shah, V. A.; Cruz-Alemida, Y.; Roy, A.; Cenko, E.; Downey, R. J.; Ferris, D. P.; Hass, C. J.; Reuter-Lorenz, P. A.; Clark, D. J.; Manini, T. M.; Seidler, R. D.
10.1101/2023.03.14.531779 — neuroscience — Posted on 2023-03-15
2451 Leveraging gene correlations in single cell transcriptomic data
Silkwood, K.; Dollinger, E.; Gervin, J.; Atwood, S.; Nie, Q.; Lander, A. D.
10.1101/2023.03.14.532643 — systems biology — Posted on 2023-03-15
2455 Optimizing Short-format Training: an International Consensus on Effective, Inclusive, and Career-spanning Professional Development in the Life Sciences and Beyond
Williams, J. J.; Tractenberg, R. E.; Batut, B.; Becker, E. A.; Brown, A. M.; Burke, M. L.; Busby, B.; Cooch, N. K.; Dillman, A. A.; Donovan, S. S.; Doyle, M. A.; van Gelder, C. W. G.; Hall, C. R.; Hertweck, K. L.; Jordan, K. L.; Jungck, J. R.; Latour, A. R.; Lindvall, J. M.; Lloret-Llinares, M.; McDowell, G. S.; Morris, R.; Mourad, T.; Nisselle, A.; Ordonez, P.; Paladin, L.; Palagi, P. M.; Sukhai, M. A.; Teal, T. K.; Woodley, L.
10.1101/2023.03.10.531570 — scientific communication and education — Posted on 2023-03-15
2459 From root to shoot; Quantifying nematode tolerance in Arabidopsis thaliana by high-throughput phenotyping of plant development
Willig, J.-J.; Sonneveld, D.; Steenbrugge, J. J. M.; Deurhof, L.; van Schaik, C. C.; Teklu, M. G.; Goverse, A.; Lozano-Torres, J. L.; Smant, G.; Sterken, M. G.
10.1101/2023.03.15.532731 — plant biology — Posted on 2023-03-15
2460 Early-adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila
Kosakamoto, H.; Obata, F.; Kuraishi, J.; Aikawa, H.; Okada, R.; Johnstone, J. N.; Onuma, T.; Piper, M. D. W.; Miura, M.
10.1101/2023.03.15.532514 — physiology — Posted on 2023-03-15
2461 Mature microRNA-binding protein QKI promotes microRNA-mediated gene silencing
Yoon, J.-H.; Min, K.-W.; Jo, M. H.; Song, M.; Ko, S.; Lee, J. W.; Shim, M. J.; Kim, K.; Park, H. B.; Ha, S.; Mun, H.; Polash, A.; Hafner, M.; Cho, J.-H.; Kim, D.-S.; Hohng, S.; Kang, S.-U.
10.1101/2023.03.15.532749 — biochemistry — Posted on 2023-03-15
2463 A new Plasmodium vivax reference genome for South American isolates
De Meulenaere, K.; Cuypers, B.; Gamboa, D.; Laukens, K.; Rosanas-Urgell, A.
10.1101/2023.03.14.532329 — genetics — Posted on 2023-03-15
2464 Using a handful of transcriptomes to detect sex-linked markers in a lizard with homomorphic sex chromosomes
Saunders, P. A.; Ferre-Ortega, C.; Hill, P.; Simakov, O.; Ezaz, T.; Burridge, C. P.; Wapstra, E.
10.1101/2023.03.14.532509 — genetics — Posted on 2023-03-15
2470 Conserving bird populations in the Anthropocene: the significance of non-breeding movements
Pokrovsky, I.; Curk, T.; Dietz, A.; Fufachev, I.; Kulikova, O.; Rossler, S.; Wikelski, M.
10.1101/2023.03.13.532370 — ecology — Posted on 2023-03-15
2472 Pathogenic Leptospira are widespread in the urban wildlife of southern California
Helman, S. K.; Tokuyama, A.; Mummah, R.; Gamble, M.; Snedden, C.; Borremans, B.; Gomez, A.; Cox, C.; Nussbaum, J.; Tweedt, I.; Haake, D.; Galloway, R.; Monzon, J.; Riley, S.; Sikich, J.; Brown, J.; Friscia, A.; Lynch, J.; Prager, K.; Lloyd-Smith, J.
10.1101/2023.03.13.531784 — ecology — Posted on 2023-03-15
2473 Uptake of plant-derived carbon and proximity to the root determine differences in temporal and spatial stability among microbial groups
Lange, M.; Azizi-Rad, M.; Dittmann, G.; Lange, D. F.; Orme, A. M.; Schroeter, S. A.; Simon, C.; Gleixner, G.
10.1101/2023.03.15.532717 — ecology — Posted on 2023-03-15
2474 Plant diversity stabilizes soil temperature
Huang, Y.; Stein, G. H.; Kolle, O.; Kuebler, K.; Schulze, E.-D.; Dong, H.; Eichenberg, D.; Gleixner, G.; Hildebrandt, A.; Lange, M.; Roscher, C.; Schielzeth, H.; Schmid, B.; Weigelt, A.; Weisser, W.; Shadaydeh, M.; Denzler, J.; Ebeling, A.; Eisenhauer, N.
10.1101/2023.03.13.532451 — ecology — Posted on 2023-03-15
2477 Learning about neurodiversity from parents - auditory gestalt perception of prelinguistic vocalisations
Zhang, D.; Lang, S.; Wilken, B.; Einspieler, C.; Neul, J. L.; Boelte, S.; Holzinger, D.; Freilinger, M.; Poustka, L.; Sigafoos, J.; Marschik, P. B.
10.1101/2023.03.13.532450 — developmental biology — Posted on 2023-03-15
2479 Adrenal extramedullary hematopoiesis as an inducible model of the adult hematopoietic niche
Schyrr, F.; Alonso-Calleja, A.; Vijaykumar, A.; Gebhard, S.; Sarkis, R.; Lopes, S. F.; Oggier, A.; De Leval, L.; Nombela-Arrieta, C.; Naveiras, O.
10.1101/2023.03.15.531679 — cell biology — Posted on 2023-03-15
2480 Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection
Fukushi, M.; Ohsawa, R.; Okinaka, Y.; Oikawa, D.; Kiyono, T.; Moriwaki, M.; Irie, T.; Oda, K.; Kamei, Y.; Tokunaga, F.; Sotomaru, Y.; Maruyama, H.; Kawakami, H.; Sakaguchi, T.
10.1101/2023.03.13.532484 — immunology — Posted on 2023-03-15
2482 A lymph node-to-tumour PD-L1+macrophage circuit antagonizes dendritic cell immunotherapy
Sprooten, J.; Vanmeerbeek, I.; Datsi, A.; Govaerts, J.; Borras, D.; Naulaerts, S.; Laureano, R.; Calvet, A.; Kuballa, M.; Sabel, M.; Rapp, M.; Knobbe-Thomsen, C.; Liu, P.; Zhao, L.; Kepp, O.; Boon, L.; Tejpar, S.; Borst, J.; Schlenner, S.; De Vleeschouwer, S.; Sorg, R.; Garg, A. D.
10.1101/2023.03.14.532534 — immunology — Posted on 2023-03-15
2483 Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling
Lee, J.; Robinson, M. E.; Sun, R.; Kume, K.; Ma, N.; Cosgun, K. N.; Chan, L. N.; Leveille, E.; Geng, H.; Vykunta, V. S.; Shy, B. R.; Marson, A.; Katz, S. G.; Chen, J.; Paietta, E.; Meffre, E.; Nagarajan, V.; Mueschen, M.
10.1101/2023.03.13.532151 — immunology — Posted on 2023-03-15
2484 Perturbomics of tumor-infiltrating NK cells
Peng, L.; Renauer, P. A.; Ye, L.; Yang, L.; Park, J. J.; Chow, R. D.; Zhang, Y.; Lin, Q.; Bai, M.; Sanchez, A.; Zhang, Y.; Lam, S. Z.; Chen, S.
10.1101/2023.03.14.532653 — immunology — Posted on 2023-03-15
2485 Divergent roles for caspase-8 and MLKL in high-fat diet induced obesity and NAFLD in mice
Tye, H.; Conos, S. A.; Djajawi, T. M.; Abdoulkader, N.; Kong, I. Y.; Kaummon, H. L.; Narayana, V. K.; Speir, M.; Gottschalk, T. A.; Emery, J.; Simpson, D. S.; Hall, C.; Vince, A. J.; Russo, S.; Crawley, R.; Rashidi, M.; Hildebrand, J.; Murphy, J. M.; Whitehead, L.; De Souza, D. P.; Masters, S. L.; Hawkins, E. D.; Murphy, A. J.; Vince, J.; Lawlor, K.
10.1101/2023.03.14.532682 — immunology — Posted on 2023-03-15
2486 Identification of a new mucosal lymphoid organ below the pharynx of teleost fish: tonsils in fish?
RESSEGUIER, J.; NGUYEN-CHI, M.-E.; WOHLMANN, J.; RIGAUDEAU, D.; SALINAS, I.; OEHLERS, S. H.; WIEGERTJES, G. F.; JOHANSEN, F.-E.; QIAO, S.-W.; KOPPANG, E. O.; VERRIER, B.; BOUDINOT, P.; GRIFFITHS, G.
10.1101/2023.03.13.532382 — immunology — Posted on 2023-03-15
2488 Human postmortem studies reveal tissue-specific differences amongst TB-patient groups
Ahimbisibwe, G.; Nakibuule, M.; Ssejjoba, M.; Oyamo, D.; Mulwana, R.; Nabulime, J.; Babirye, F.; Kizito, A.; Lekuya, H.; Adakun, S.; Kyazze, A.; Lukande, R.; Baluku, J.; Biraro, I.; Cose, S.
10.1101/2023.03.14.532701 — immunology — Posted on 2023-03-15
2491 BrainSuite BIDS App: Containerized Workflows for MRI Analysis
Kim, Y.; Joshi, A. A.; Choi, S.; Joshi, S. H.; Bhushan, C.; Varadarajan, D.; Haldar, J. P.; Leahy, R. M.; Shattuck, D. W.
10.1101/2023.03.14.532686 — neuroscience — Posted on 2023-03-15
2492 NEURD: A mesh decomposition framework forautomated proofreading and morphologicalanalysis of neuronal EM reconstructions
Celii, B.; Papadopoulos, S.; Ding, Z.; Fahey, P. G.; Wang, E.; Papadopoulos, C.; Kunin, A.; Patel, S.; Bae, J. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Cobos, E.; Dorkenwald, S.; Elabbady, L.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Schneider-Mizell, C. M.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yu, S.-c.; Yin, W.; Xenes, D.; Kitchell, L. M.; Rivlin, P. K.; Rose, V. A.; Bishop
10.1101/2023.03.14.532674 — neuroscience — Posted on 2023-03-15
2494 Monitoring Alzheimer's Disease via Ultraweak Photon Emission
Sefati, N.; Esmaeilpour, T.; Salari, V.; Zarifkar, A.; Dehghani, F.; Khorsand Ghaffari, M.; Csaszar, N.; Bokkon, I.; Rodrigues, S.; Oblak, D.
10.1101/2023.03.14.532685 — neuroscience — Posted on 2023-03-15
2496 Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity and emerges early during adult neurogenesis
Roessler, N.; Jungenitz, T.; Sigler, A.; Bird, A.; Mittag, M.; Rhee, J.; Deller, T.; Cuntz, H. J.; Brose, N.; Schwarzacher, S.; Jedlicka, P.
10.1101/2023.03.15.532740 — neuroscience — Posted on 2023-03-15
2498 Hepatic IRE1 Protects Against Septic Cardiac Failure
Li, M.; Berton, R. R.; Qian, Q.; Maschek, J. A.; Chen, B.; Barroso, E.; Rauckhorst, A.; Griffith, T. S.; Taylor, E. B.; Cox, J. E.; Badovinac, V. P.; Hotamisligil, G. S.; Song, L.-s.; Yang, L.
10.1101/2023.03.14.532202 — pathology — Posted on 2023-03-15
2499 Extracellular vesicle-localized miR-203 mediates neural crest-placode communication required for trigeminal ganglia formation
Bernardi, Y. E.; Sanchez-Vasquez, E.; Piacentino, M. L.; Urrutia, H.; Rossi, I.; Alcantara Saraiva, K. L.; Pereira-Neves, A.; Ramirez, M. I.; Bronner, M. E.; de Miguel, N.; Strobl-Mazzulla, P. H.
10.1101/2023.03.14.532527 — developmental biology — Posted on 2023-03-15
2500 A novel ground truth dataset enables robust 3D nuclear instance segmentation in early mouse embryos
Nunley, H.; Shao, B.; Grover, P.; Singh, J.; Joyce, B.; Kim-Yip, R.; Kohrman, A.; Watters, A.; Gal, Z.; Kickuth, A.; Chalifoux, M.; Shvartsman, S.; Posfai, E.; Brown, L.
10.1101/2023.03.14.532646 — developmental biology — Posted on 2023-03-15
2501 Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations
Bantounas, I.; Rooney, K. M.; Lopes, F. M.; Tengku, F.; Woods, S.; Zeef, L. A.; Kuba, S. Y.; Bates, N.; Hummelgaard, S.; Hillman, K. A.; Cereghini, S.; Woolf, A. S.; Kimber, S. J.
10.1101/2023.03.14.532598 — developmental biology — Posted on 2023-03-15
2502 Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues
Park, K.; Jayadev, R.; Payne, S. G.; Kenny-Ganzert, I. W.; Chi, Q.; Costa, D. S.; Ramos-Lewis, W.; Balachandar Thendral, S.; Sherwood, D. R.
10.1101/2023.03.14.532639 — developmental biology — Posted on 2023-03-15
2503 A Novel Transcription Factor Combination for Direct Reprogramming to a Spontaneously Contracting Human Cardiomyocyte-like State
Tejeda, M. R.; Fonoudi, H.; Weddle, C. J.; DeKeyser, J.-M.; Lenny, B.; Fetterman, A. K.; Magdy, T.; Sapkota, Y.; Epting, C.; Burridge, P. W.
10.1101/2023.03.14.532629 — cell biology — Posted on 2023-03-15
2505 Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops
Harada, T.; Kalfon, J.; Perez, M. W.; Eagle, K.; Braes, F. D.; Batley, R.; Heshmati, Y.; Ferrucio, J. X.; Ewers, J.; Mehta, S.; Kossenkov, A.; Ellegast, J. M.; Bowker, A.; Wickramasinghe, J.; Nabet, B.; Paralkar, V. R.; Dharia, N. V.; Stegmaier, K.; Orkin, S. H.; Pimkin, M.
10.1101/2023.03.13.532438 — systems biology — Posted on 2023-03-15
2507 A bi-kinase module sensitizes and potentiates plant immune signaling
Koester, P.; He, G.; Dong, Q.; Hake, K.; Schmitz-Thom, I.; Heinkow, P.; Eirich, J.; Wallrad, L.; Hashimoto, K.; Schueltke, S.; Finkemeier, I.; Romeis, T.; Kudla, J.
10.1101/2023.03.14.532616 — plant biology — Posted on 2023-03-15
2511 Spatial architecture of high-grade glioma reveals tumor heterogeneity within distinct domains
Moffet, J. J. D.; Fatunla, O. E.; Freytag, L.; Jones, J. J.; Roberts-Thomson, S. J.; Pavenko, A.; Scoville, D. K.; Zhang, L.; Liang, Y.; Morokoff, A. P.; Whittle, J. R.; Freytag, S.; Best, S. A.
10.1101/2023.03.13.531204 — cancer biology — Posted on 2023-03-15
2512 Loss-of-SIRT7 sensitizes hepatocellular carcinoma to sorafenib through the regulation of ERK Phosphorylation
Kim, Y.; Jung, K.-Y.; Kim, Y. H.; Xu, P.; Jo, Y.; Kang, B. E.; Pandit, N.; Kwon, J.; Gariani, K.; Gariani, J.; Lee, J.; Verbeek, J.; Nam, S.; Bae, S.-J.; Ha, K.-T.; Yi, H.-S.; Shong, M.; Kim, K.-H.; Kim, D.; Lee, C.-W.; Jung, H. J.; Kim, K. R.; Schoonjans, K.; Ryu, D.; Auwerx, J.
10.1101/2023.03.13.531998 — cancer biology — Posted on 2023-03-15
2516 A thermodynamic analysis of CLC transporter dimerization in lipid bilayers
Chadda, R.; Lee, T.; Sandal, P.; Mahoney-Kruszka, R.; Robertson, J. L.
10.1101/2023.03.14.532678 — biophysics — Posted on 2023-03-15
2518 What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds
Durairaj, J.; Waterhouse, A.; Mets, T.; Brodiazhenko, T.; Abdullah, M.; Akdel, M.; Andreeva, A.; Bateman, A.; Hauryliuk, V.; Tenson, T.; Schwede, T.; Pereira, J.
10.1101/2023.03.14.532539 — bioinformatics — Posted on 2023-03-15
2519 FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in-vitro toxicology and pharmacology
Finkel, S.; Sweet, S.; Locke, T.; Smith, S.; Wang, Z.; Sandini, C.; Imredy, J.; He, Y.; Durante, M.; Lagrutta, A.; Feinberg, A.; Lee, A.
10.1101/2023.03.13.528447 — bioengineering — Posted on 2023-03-15
2521 Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
Edman, N. I.; Redler, R. L.; Phal, A.; Schlichthaerle, T.; Srivatsan, S. R.; Etemadi, A.; An, S.; Favor, A.; Ehnes, D.; Li, Z.; Praetorius, F.; Gordon, M.; Yang, W.; Coventry, B.; Hicks, D. R.; Cao, L.; Bethel, N.; Heine, P.; Murray, A. N.; Gerben, S.; Carter, L.; Miranda, M.; Negahdari, B.; Lee, S.; Trapnell, C.; Stewart, L.; Ekiert, D. C.; Schlessinger, J.; Shendure, J.; Bhabha, G.; Ruohola-Baker, H.; Baker, D.
10.1101/2023.03.14.532666 — bioengineering — Posted on 2023-03-15
2523 Sulfide oxidation promotes hypoxic angiogenesis and neovascularization
Kumar, R.; Vitvitsky, V.; Seth, P.; Hiraki, H. L.; Bell, H.; Andren, A.; Singhal, R.; Baker, B.; Lyssiotis, C. A.; Shah, Y. M.; Banerjee, R.
10.1101/2023.03.14.532677 — biochemistry — Posted on 2023-03-15
2526 Portable X-ray fluorescence for identifying harmful lead exposure in wild mammals through hair analysis
Jones, E. M.; Bengsen, A. J.; Specht, A. J.; Koch, A. J.; Hamede, R. K.; Jones, M. E.; Hampton, J. O.
10.1101/2023.03.13.531209 — ecology — Posted on 2023-03-15
2530 Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages
Ren, P.; Hu, Y.; Peng, L.; Yang, L.; Suzuki, K.; Fang, Z.; Bai, M.; Zhou, L.; Feng, Y.; Zou, Y.; Xiong, Y.; Chen, S.
10.1101/2022.08.09.503414 — immunology — Posted on 2023-03-15
2533 Conformational dynamics and target-dependent myristoyl switch of calcineurin B homologous protein 3
Becker, F.; Fuchs, S.; Refisch, L.; Drepper, F.; Bildl, W.; Schulte, U.; Liang, S.; Heinicke, J. I.; Hansen, S. C.; Kreutz, C.; Warscheid, B.; Fakler, B.; Mymrikov, E. V.; Hunte, C.
10.1101/2022.09.23.509142 — biochemistry — Posted on 2023-03-15
2535 Adiponectin Reverses Beta-Cell Damage and Impaired Insulin Secretion Induced by Obesity
Munhoz, A. C.; Serna, J. D. C.; Vilas-Boas, E. A.; Caldeira da Silva, C. C.; dos Santos, T. G.; Mosele, F. C.; Felisbino, S. L.; Martins, V. R.; Kowaltowski, A. J.
10.1101/2022.07.22.501128 — biochemistry — Posted on 2023-03-15
2541 Transposon-encoded nucleases use guide RNAs to selfishly bias their inheritance
Meers, C.; Le, H.; Pesari, S. R.; Hoffmann, F. T.; Walker, M. W. G.; Gezelle, J.; Sternberg, S. H.
10.1101/2023.03.14.532601 — molecular biology — Posted on 2023-03-14
2543 Multiscale mapping of transcriptomic signatures for cardiotoxic drugs
Hansen, J.; Xiong, Y.; Dhanan, P.; Hu, B.; Yadaw, A. S.; Jayaraman, G.; Tolentino, R.; Chen, Y.; Beaumont, K. G.; Sebra, R.; Vidovic, D.; Schuerer, S. C.; Goldfarb, J.; Gallo, J.; Birtwistle, M. R.; Sobie, E. R.; Azeloglu, E. U.; Berger, S.; Chan, A.; Schaniel, C.; Dubois, N. C.; Iyengar, R.
10.1101/2021.11.02.466774 — systems biology — Posted on 2023-03-14
2544 Engineering the biological conversion of formate into crotonate in Cupriavidus necator
Collas, F.; Dronsella, B. B.; Kubis, A.; Schann, K.; Binder, S.; Arto, N.; Claassens, N. J.; Kensy, F.; Orsi, E.
10.1101/2023.03.14.532570 — synthetic biology — Posted on 2023-03-14
2546 Stimulated Raman Photothermal Microscopy towards Ultrasensitive Chemical Imaging
Zhu, Y.; Ge, X.; Ni, H.; Yin, J.; Lin, H.; Wang, L.; Tan, Y.; Prabhu Dessai, C. V.; Cheng, J.-X.
10.1101/2023.03.06.531387 — bioengineering — Posted on 2023-03-14
2547 Single molecule MATAC-seq reveals key determinants of DNA replication origin efficiency
Chanou, A.; Weiss, M.; Holler, K.; Straub, T.; Krietsch, J.; Sanchi, A.; Ummethum, H.; Lee, C. S. K.; Kruse, E.; Trauner, M.; Werner, M.; Lalonde, M.; Lopes, M.; Scialdone, A.; Hamperl, S.
10.1101/2023.03.14.532513 — biochemistry — Posted on 2023-03-14
2548 Phosphorylation barcodes direct biased chemokine signaling at CXCR3
Eiger, D. S.; Smith, J. S.; Shi, T.; Stepniewski, T. M.; Tsai, C.-F.; Honeycutt, C.; Boldiszar, N.; Gardner, J.; Nicora, C. D.; Moghieb, A. M.; Kawakami, K.; Choi, I.; Zheng, K.; Warman, A.; Alagesan, P.; Knape, N. M.; Huang, O.; Silverman, J. D.; Smith, R. D.; Inoue, A.; Selent, J.; Jacobs, J. M.; Rajagopal, S.
10.1101/2023.03.14.532634 — biochemistry — Posted on 2023-03-14
2551 Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering
Dong, M. B.; Tang, K.; Zhou, X.; Shen, J.; Chen, K.; Kim, H. R.; Zhou, J.; Cao, H.; Vandenbulcke, E.; Zhang, Y.; Chow, R. D.; Du, A.; Suzuki, K.; Fang, S.-Y.; Majety, M.; Dai, X.; Chen, S.
10.1101/2023.03.14.532657 — genetics — Posted on 2023-03-14
2552 An increase in atypical petal numbers during a shift to autogamy in a coastal sand verbena and potential evolutionary mechanisms
LoPresti, E.; Mickley, J.; Darby, A.; Eckert, C. G.; Foisy, M.; Girvin, C.; Jaeger, S.; Toll, K.; Van Natto, A. C.; Weber, M. G.
10.1101/2021.01.03.425117 — evolutionary biology — Posted on 2023-03-14
2553 Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs
Zhou, Y.; Sun, H.; Vargas-Blanco, D. A.; Martini, M. C.; Rapiejko, A. R.; Chase, M. R.; Joubran, S. R.; Davis, A. B.; Dainis, J. P.; Kelly, J. M.; Ioerger, T. R.; Roberts, L. A.; Fortune, S. M.; Shell, S. S.
10.1101/2023.03.14.532454 — molecular biology — Posted on 2023-03-14
2554 The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation
Khella, M. S.; Schnee, P.; Weirich, S.; Bui, T.; Broehm, A.; Bashtrykov, P.; Pleiss, J.; Jeltsch, A.
10.1101/2023.03.13.532367 — molecular biology — Posted on 2023-03-14
2555 Quorum Sensing Modulates Bacterial Virulence and Colonization Dynamics During an Enteric Infection
Pena-Diaz, J.; Woodward, S. E.; Creus-Cuadros, A.; Serapio-Palacios, A.; Deng, W.; Finlay, B. B.
10.1101/2023.03.14.532656 — microbiology — Posted on 2023-03-14
2556 Deciphering the gut microbiome of grass carp through multi-omics approach
Li, M.; Liang, H.; Yang, H.; Ding, Q.; Xia, R.; Chen, J.; Zhou, W.; Yang, Y.; Zhang, Z.; Yao, Y.; Ran, C.; Zhou, Z.
10.1101/2023.03.14.532499 — microbiology — Posted on 2023-03-14
2557 Mycobacterium trehalose polyphleates are required for mycobacteriophage infection
Wetzel, K. S.; Illouz, M.; Abad, L.; Aull, H. G.; Russell, D. A.; Garlena, R. A.; Cristinziano, M.; Malmsheimer, S.; Chalut, C.; Hatfull, G. F.; Kremer, L.
10.1101/2023.03.14.532567 — microbiology — Posted on 2023-03-14
2558 Evolution of the CRISPR-Cas9 defence system following a bacterial host shift
Ipoutcha, T.; Tsarmpopoulos, I.; Gourgues, G.; Baby, V.; Dubos, P.; Hill, G. E.; Dowling, A.; Arfi, Y.; Lartigue, C.; Thebault, P.; Bonneaud, C.; Sirand-Pugnet, P.
10.1101/2023.03.14.532377 — microbiology — Posted on 2023-03-14
2559 Age-related epithelial defects limit thymic function and regeneration
Kousa, A. I.; Jahn, L.; Zhao, K.; Flores, A. E.; Granadier, D.; Cooper, K.; Sheridan, J. M.; Lemarquis, A.; Sikkema, L.; Argyropoulos, K. V.; Tsai, J.; Lazrak, A.; Nichols, K.; Lee, N.; Ghale, R.; Malard, F.; Andrlova, H.; Gomes, A. L.; Velardi, E.; Youssef, S.; da Silva, M. B.; Docampo, M.; Sharma, R.; Mazutis, L.; Wimmer, V. C.; Rogers, K. L.; DeWolf, S.; Gipson, B.; Setty, M.; Pe'er, D.; Manley, N. R.; Gray, D. H.; Dudakov, J. A.; van den Brink, M. R.
10.1101/2021.12.16.472014 — immunology — Posted on 2023-03-14
2560 Combining fusion of cells with CRISPR-Cas9 editing for the cloning of large DNA fragments or complete bacterial genomes in yeast.
GUESDON, G.; GOURGUES, G.; RIDEAU, F.; IPOUTCHA, T.; MANSO-SILVAN, L.; JULES, M.; SIRAND-PUGNET, P.; BLANCHARD, A.; LARTIGUE, C.
10.1101/2023.03.14.531922 — synthetic biology — Posted on 2023-03-14
2563 Hem25p is a mitochondrial IPP transporter
Tai, J.; Guerra, R. M.; Rogers, S. W.; Fang, Z.; Muehlbauer, L. K.; Shishkova, E.; Overmyer, K. A.; Coon, J. J.; Pagliarini, D. J.
10.1101/2023.03.14.532620 — biochemistry — Posted on 2023-03-14
2564 Genomic surveillance reveals circulation of multiple variants and lineages of SARS-CoV-2 during COVID-19 pandemic in Indian city of Bengaluru
S, D.; Kumar, V.; Kathirvel, K.; Vadnala, R. N.; Mishra, S.; Shelar, B.; Marate, S.; CP, L.; K, S. D.; Bhardwaj, M.; Pandit, A.; Mayor, S.; Ramakrishnan, U.; Notani, D.
10.1101/2023.03.14.532352 — genomics — Posted on 2023-03-14
2565 A Cre-dependent massively parallel reporter assay allows for cell-type specific assessment of the functional effects of non-coding elements in vivo
Lagunas, T.; Plassmeyer, S. P.; Fischer, A. D.; Friedman, R. Z.; Rieger, M. A.; Lucero, A. F. A.; An, J.-Y.; Sanders, S. J.; Cohen, B. A.; Dougherty, J. D.
10.1101/2021.05.17.444514 — genetics — Posted on 2023-03-14
2569 Protection of catalytic cofactors by polypeptides as a driver for the emergence of primordial enzymes
Gutierrez-Rus, L. I.; Gamiz-Arco, G.; Gavira, J. A.; Gaucher, E. A.; Risso, V. A.; Sanchez-Ruiz, J. M.
10.1101/2023.03.14.532612 — molecular biology — Posted on 2023-03-14
2570 Gut microbial community in proboscis monkeys: implications for effects of geographical and social factors
Jose, L.; Lee, W.; Hanya, G.; Tuuga, A.; Goossens, B.; Tangah, J.; Matsuda, I.; Subbiah, V. K.
10.1101/2023.03.14.532648 — microbiology — Posted on 2023-03-14
2572 Congruent downy mildew-associated microbiomes reduce plant disease and function as transferable resistobiomes
Goossens, P.; Spooren, J.; Baremans, K.; Andel, A.; Lapin, D.; Echobardo, N.; Pieterse, C.; Van den Ackerveken, G.; Berendsen, R.
10.1101/2023.03.14.532520 — microbiology — Posted on 2023-03-14
2573 RSV infection does not induce EMT
Talukdar, S. N.; McGregor, B. A.; Osan, J. K.; Hur, J.; Mehedi, M.
10.1101/2023.03.13.532506 — microbiology — Posted on 2023-03-14
2575 Reverse genetic screen identifies malaria parasite genes required for gametocyte-to-sporozoite development in its mosquito host
Ukegbu, C. V.; Gomes, A. R.; Giorgalli, M.; Campos, M.; Bailey, A. J.; Besson, T. R.; Billker, O.; Vlachou, D.; Christophides, G. K.
10.1101/2023.03.14.532540 — microbiology — Posted on 2023-03-14
2576 Lactiplantibacillus plantarum uses ecologically relevant, exogenous quinones for extracellular electron transfer
Stevens, E. T.; van Beeck, W.; Blackburn, B.; Tejedor-Sanz, S.; Rasmussen, A. R. M.; Mevers, E.; Ajo-Franklin, C.; Marco, M. L.
10.1101/2023.03.13.532228 — microbiology — Posted on 2023-03-14
2580 Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants
Pavan, M. F.; Bok, M.; Betanzos San Juan, R.; Malito, J. P.; Marcoppido, G. A.; Franco, D. R.; Militello, D. A.; Schammas, J. M.; Bari, S.; Stone, W. B.; Lopez, K.; Porier, D.; Muller, J.; Auguste, A. J.; Yuan, L.; Wigdorovitz, A.; Parreno, V.; Ibanez, L. I.
10.1101/2023.03.14.532528 — immunology — Posted on 2023-03-14
2581 Running modulates primate and rodent visual cortex differently
Liska, J. P.; Rowley, D. P.; Nguyen, T. T. K.; Muthmann, J.-O.; Butts, D. A.; Yates, J. L.; Huk, A. C.
10.1101/2022.06.13.495712 — neuroscience — Posted on 2023-03-14
2582 Aging decreases the lateralization of gravity-related effort minimization during vertical arm movements
Poirier, G.; Papaxanthis, C.; Lebigre, M.; Juranville, A.; Mathieu, R.; Savoye-Laurens, T.; Manckoundia, P.; Mourey, F.; Gaveau, J.
10.1101/2021.10.26.465988 — neuroscience — Posted on 2023-03-14
2584 A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a non-hemophiliac state
Teranishi-Ikawa, Y.; Soeda, T.; Koga, H.; Yamaguchi, K.; Kato, K.; Esaki, K.; Asanuma, K.; Funaki, M.; Ichiki, M.; Ikuta, Y.; Ito, S.; Joyashiki, E.; Komatsu, S.-I.; Muto, A.; Nishimura, K.; Okuda, M.; Sanada, H.; Sato, M.; Shibahara, N.; Wakabayashi, T.; Yamaguchi, K.; Matsusaki, A.; Sampei, Z.; Shiraiwa, H.; Konishi, H.; Kawabe, Y.; Hattori, K.; Kitazawa, T.; Igawa, T.
10.1101/2022.12.19.520692 — bioengineering — Posted on 2023-03-14
2586 One thousand soils for molecular understanding of belowground carbon cycling
Bowman, M.; Heath, A. E.; Varga, T.; Battu, A.; Chu, R. K.; Toyoda, J. G.; Cheeke, T.; Porter, S.; Moffett, K.; Letendre, B.; Qafoku, O.; Bargar, J.; Mans, D.; Hess, N.; Graham, E. B.
10.1101/2022.12.12.520098 — ecology — Posted on 2023-03-14
2587 Oct1 cooperates with Smad transcription factors to promote mesodermal lineage specification
Perovanovic, J.; Wu, Y.; Abewe, H.; Shen, Z.; Hughes, E. P.; Gertz, J.; Chandrasekharan, M. B.; Tantin, D.
10.1101/2020.12.01.406488 — developmental biology — Posted on 2023-03-14
2590 Deep physico-chemical characterization of individual serum antibody responses against SARS-CoV-2 RBD using a dual titration microspot assay
Kovacs, A.; Herincs, Z.; Papp, K.; Kaczmarek, J. Z.; Larsen, D. N.; Stage, P.; Bereczki, L.; Ujhelyi, E.; Pfeil, T.; Prechl, J.
10.1101/2023.03.14.532012 — immunology — Posted on 2023-03-14
2591 Murine Alveolar Macrophages Rapidly Accumulate Intranasally Administered SARS-CoV-2 Spike Protein leading to Neutrophil Recruitment and Damage
Park, C.; Hwang, I.-Y.; Yan, S. L.-S.; Vimonpatranon, S.; Wei, D.; Van Ryk, D.; Cicala, C.; Arthos, J.; Kehrl, J. H.
10.1101/2023.03.13.532446 — immunology — Posted on 2023-03-14
2592 Geneneralising the HCP multimodal cortical parcellation to UK Biobank
Williams, L. Z. J.; Glasser, M. F.; Alfaro-Almagro, F.; Dahan, S.; Fawaz, A.; Coalson, T. S.; Fitzgibbon, S. P.; Suliman, M.; Van Essen, D. C.; Smith, S. M.; Edwards, A. D.; Robinson, E. C.
10.1101/2023.03.14.532531 — neuroscience — Posted on 2023-03-14
2593 State-dependent GABAergic regulation of striatal spiny projection neuron excitability
Day, M.; Belal, M.; Surmeier, C.; Melendez-Zaidi, A.; Tkatch, T.; Clarke, V. R. J.; Surmeier, D. J.
10.1101/2023.03.14.532627 — neuroscience — Posted on 2023-03-14
2594 PhAT: A flexible open-source GUI-driven toolkit for photometry analysis
Murphy, K. Z.; Haile, E.; McTigue, A.; Pierce, A. F.; Donaldson, Z.
10.1101/2023.03.14.532489 — neuroscience — Posted on 2023-03-14
2595 VIP interneurons regulate cortical size tuning and visual perception
Ferguson, K. A.; Salameh, J.; Alba, C.; Selwyn, H.; Barnes, C.; Lohani, S.; Cardin, J. A.
10.1101/2023.03.14.532664 — neuroscience — Posted on 2023-03-14
2600 Speed-dependent optimization of gravity effects for motor control
Poirier, G.; Mourey, F.; Sirandre, C.; Papaxanthis, C.; Gaveau, J.
10.1101/2023.03.14.532654 — neuroscience — Posted on 2023-03-14
2602 Pattern completion and disruption characterize contextual modulation in mouse visual cortex
Fu, J.; Shrinivasan, S.; Ponder, K.; Muhammad, T.; Ding, Z.; Wang, E.; Ding, Z.; Tran, D. T.; Fahey, P. G.; Papadopoulos, S.; Patel, S.; Reimer, J.; Ecker, A. S.; Pitkow, X.; Haefner, R. M.; Sinz, F. H.; Franke, K.; Tolias, A. S.
10.1101/2023.03.13.532473 — neuroscience — Posted on 2023-03-14
2607 Sex differences in neural representations of social and nonsocial reward in the medial prefrontal cortex.
Isaac, J.; Karkare, S.; Balasubramanian, H.; Schappaugh, N.; Javier, J.; Rashid, M.; Murugan, M.
10.1101/2023.03.09.531947 — neuroscience — Posted on 2023-03-14
2608 Larval microbiota primes the Drosophila adult gustatory response
Montanari, M.; Maniere, G.; Berthelot-Grosjean, M.; Dusabyinema, Y.; Gillet, B.; Grosjean, Y.; Kurz, C. L.; Royet, J.
10.1101/2023.03.14.532561 — animal behavior and cognition — Posted on 2023-03-14
2609 Mechanisms of octopus arm search behavior without visual feedback
Sivitilli, D. M.; Strong, T.; Weertman, W.; Ullmann, J.; Smith, J. R.; Gire, D. H.
10.1101/2023.03.13.532148 — animal behavior and cognition — Posted on 2023-03-14
2610 Effect of elevated embryonic incubation temperature on the temperature preference of juvenile lake (Coregonus clupeaformis) and round whitefish (Prosopium cylindraceum)
Harman, A. A.; Mahoney, H.; Thompson, W. A.; Fuzzen, M. L.; Aggarwhal, B.; Laframboise, L.; Boreham, D. R.; Manzon, R. G.; Somers, C. M.; Wilson, J. Y.
10.1101/2023.03.13.532459 — animal behavior and cognition — Posted on 2023-03-14
2613 Functional connectomics reveals general wiring rule in mouse visual cortex
Ding, Z.; Fahey, P. G.; Papadopoulos, S.; Wang, E.; Celii, B.; Papadopoulos, C.; Kunin, A.; Chang, A.; Fu, J.; Ding, Z.; Patel, S.; Ponder, K.; Bae, J. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Cobos, E.; Dorkenwald, S.; Elabbady, L.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Schneider-Mizell, C. M.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yin, W.; Yu, S.-c.; Froudarakis, E.; Sinz
10.1101/2023.03.13.531369 — neuroscience — Posted on 2023-03-14
2614 Development of prefrontal corticostriatal connectivity in mice
Mesias, R. E.; Zaki, Y.; Guevara, C. A.; Friedman, L. G.; Hussein, A.; Therrien, K.; Magee, A. R.; Tzavaras, N.; Del Valle, P.; Baxter, M. G.; Huntley, G. W.; Benson, D. L.
10.1101/2023.03.14.532475 — neuroscience — Posted on 2023-03-14
2616 Aversive experience drives offline ensemble reactivation to link memories across days
Zaki, Y.; Pennington, Z. T.; Morales-Rodriguez, D.; Francisco, T. R.; LaBanca, A. R.; Dong, Z.; Segura, S. C.; Silva, A. J.; Shuman, T.; Fenton, A.; Rajan, K.; Cai, D. J.
10.1101/2023.03.13.532469 — neuroscience — Posted on 2023-03-14
2618 Nocturnal increase in cerebrospinal fluid secretion as a regulator of intracranial pressure
Steffensen, A. B.; Edelbo, B. L.; Barbuskaite, D.; Andreassen, S. N.; Olsen, M. H.; Moeller, K.; MacAulay, N.
10.1101/2023.03.14.532581 — neuroscience — Posted on 2023-03-14
2622 Phosphorylation of pyruvate dehydrogenase marks the inhibition of in vivo neuronal activity
Dong, Y.; Wang, Y.; Qi, T.; Zhang, X.; Shen, L.; Ma, J.; Pang, Z.; McClatchy, D. B.; Lal, N.; Wang, K.; Xie, Y.; Polli, F.; Maximov, A.; Augustine, V.; Cline, H. T.; Yates, J. R.; Ye, L.
10.1101/2023.03.13.532494 — neuroscience — Posted on 2023-03-14
2624 Lifespan Neurodegeneration Of The Human Brain In Multiple Sclerosis
Coupe, P.; Planche, V.; Mansencal, B.; Kamraoui, R. A.; Koubiyr, I.; Manjon, J.; Tourdias, T.
10.1101/2023.03.14.532535 — neuroscience — Posted on 2023-03-14
2626 Beta bursts correlate with synchronization of movements to rhythmic sounds
Chen, Q.; McAllister, C. J.; Elliott, M. T.; Shapiro, K. L.; Hanslmayr, S.
10.1101/2023.03.14.532353 — neuroscience — Posted on 2023-03-14
2628 Cardiopulmonary structural, functional and immune-alterations in a Down syndrome mouse model and upon modulation of EGCG
Tielemans, B.; Llambrich, S.; Seldeslachts, L.; Cremer, J.; Tsui, H.-C.; Jonckheere, A.-C.; Marain, F.; Riedel, M.; Wouters, J.; Herzen, J.; Leszczynski, B.; Verbeken, E.; Vanoirbeek, J.; Vande Velde, G.
10.1101/2023.03.13.532396 — systems biology — Posted on 2023-03-14
2629 Spatially-resolved metabolomic identifies colibactin-specific principles of reprogrammed lipid metabolism to promote cancer progression.
de Oliveira Alves, N.; Boulard, O.; Vaysse, A.; Dalmasso, G.; Nikitina, D.; Ruez, R.; Pedron, T.; Bergstein, E.; Sauvanet, P.; Letourneur, D.; Godfraind, C.; Najjar, I.; Lemichez, E.; Iovanna, J. L.; Mestivier, D.; Barnich, N.; Sansonetti, P.; Malabat, C.; Monot, M.; Kennedy, S.; Mettouchi, A.; Bonnet, R.; Sobhani, I.; Chamaillard, M.
10.1101/2023.03.13.523827 — cancer biology — Posted on 2023-03-14
2630 Swimming, Feeding and Inversion of Multicellular Choanoflagellate Sheets
Fung, L.; Konkol, A.; Ishikawa, T.; Larson, B.; Brunet, T.; Goldstein, R. E.
10.1101/2023.03.14.532283 — biophysics — Posted on 2023-03-14
2631 The landscape of cancer rewired GPCR signaling axes
Raimondi, F.; Arora, C.; Matic, M.; Rosa, N. D. O.; Nemati, L.; Clubb, L.; Kargas, G.; Vukotic, R.; Licata, L.; Wu, G.; Gutkind, J. S.
10.1101/2023.03.13.532291 — bioinformatics — Posted on 2023-03-14
2635 Delayed postglacial colonization of Betula in Iceland and the circum North Atlantic
Harning, D. J.; Sacco, S.; Thordarson, T.; Sepulveda, J.; Shapiro, B.; Geirsdottir, A.; Miller, G. H.
10.1101/2023.03.13.532414 — ecology — Posted on 2023-03-14
2639 LiverZap: A chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration
Ambrosio, E. M. M. G.; Bailey, C. S. L.; Unterweger, I. A.; Christensen, J. B.; Bruchez, M.; Lundegaard, P. R.; Ober, E. A.
10.1101/2023.03.13.531762 — cell biology — Posted on 2023-03-14
2641 The Role of Terminal Uridyl Transferases in the Circadian Rhythm
Song, W.; Wang, J.; Piao, W.; Yang, Y.; Son, A.; Chang, H.; Wen, X.; Zhang, H.; Li, C.; Na, D.; Lu, Y.; Menet, J.; Kim, V. N.; Jin, H.
10.1101/2023.03.13.516290 — molecular biology — Posted on 2023-03-14
2642 Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion
Platzer, R.; Hellmeier, J.; Gohring, J.; Doel-Perez, I.; Schatzlmaier, P.; Bodner, C.; Schuetz, G. J.; Sevcsik, E.; Stockinger, H.; Brameshuber, M.; Huppa, J. B.
10.1101/2023.03.13.532401 — immunology — Posted on 2023-03-14
2643 Using Recognition Testing to Support Semantic Learning in Developmental Amnesia
Elward, R. L.; Limond, J.; Chareyron, L. J.; Ethapemi, J.; Vargha-Khadem, F.
10.1101/2023.03.13.532399 — neuroscience — Posted on 2023-03-14
2645 TimeTeller: a tool to probe the circadian clock as a multigene dynamical system
Vlachou, D.; Veretennikova, M.; Usselmann, L.; Vasilyev, V.; Ott, S.; Bjarnason, G. A.; Dallmann, R.; Levi, F.; Rand, D. A.
10.1101/2023.03.14.532177 — systems biology — Posted on 2023-03-14
2651 Tumour Extracellular Vesicles Induce Neutrophil Extracellular Traps To Promote Lymph Node Metastasis
SU, X.; Brassard, A.; Bartolomucci, A.; Dhoparee-Dooma, I.; Qiu, Q.; Tsering, T.; Rohanizadeh, R.; Koufos, O.; Giannias, B.; Bourdeau, F.; Feng, L.; Leo, S.; Sangwan, V.; Tankel, J.; Quail, D.; Spicer, J.; Burnier, J. V.; Bailey, S. D.; Ferri, L.; Cools-Lartigue, J.
10.1101/2023.03.13.532413 — cancer biology — Posted on 2023-03-14
2652 Signal Transduction and Kinase Control in Nanodisc Reconstituted E. coli Aerotaxis Receptor
Maschmann, Z. A.; Chandrasekaran, S.; Anderson, E. T.; Fu, Q.; Freed, J. H.; Crane, B. R.
10.1101/2023.03.13.532224 — biophysics — Posted on 2023-03-14
2653 First crystal structure of double knotted protein TrmD-Tm1570 - inside from degradation perspective
Bruno da Silva, F.; Lewandowska, I.; Kluza, A.; Niewieczerzal, S.; Augustyniak, R.; Sulkowska, J. I.
10.1101/2023.03.13.532328 — biophysics — Posted on 2023-03-14
2654 Decoding optimal ligand design for multicomponent condensates
Galagedera, S. K. K.; Dao, T. P.; Enos, S. E.; Chaudhuri, A.; Schmit, J. D.; Castaneda, C. A.
10.1101/2023.03.13.532222 — biophysics — Posted on 2023-03-14
2660 B12-dependent virioplankton demonstrate interseasonal dynamics and associate with a diversity of pelagic bacterioplankton
Wu, L.-Y.; Piedade, G. J.; Moore, R. M.; Harrison, A. O.; Martins, A. M.; Bidle, K. D.; Polson, S. W.; Sakowski, E.; Nissimov, J. I.; Dums, J. T.; Ferrell, B. D.; Wommack, K. E.
10.1101/2023.03.13.532061 — ecology — Posted on 2023-03-14
2665 HEATR5B associates with dynein-dynactin and selectively promotes motility of AP1-bound endosomal membranes
Madan, V.; Albacete Albacete, L.; Jin, L.; Scaturro, P.; Watson, J. L.; Muschalik, N.; Begum, F.; Boulanger, J.; Bauer, K.; Kiebler, M. A.; Derivery, E.; Bullock, S. L.
10.1101/2023.03.14.532574 — cell biology — Posted on 2023-03-14
2666 Overexpression of IkappaBalpha modulates NF-kappaB activation of inflammatory target gene expression
Downton, P.; Bagnall, J. S.; England, H.; Spiller, D. G.; Humphreys, N.; Jackson, D. A.; Paszek, P.; White, M. R. H.; Adamson, A. D.
10.1101/2023.03.14.532132 — cell biology — Posted on 2023-03-14
2667 Vertical transmission of African-lineage Zika virus through the fetal membranes in a rhesus Macaque (Macaca mulatta) model
Koenig, M. R.; Mitzey, A. M.; Zeng, X.; Reyes, L.; Simmons, H. A.; Morgan, T. K.; Bohm, E. K.; Pritchard, J. C.; Schmidt, J. A.; Ren, E.; Jaimes, F. L.; Winston, E.; Basu, P.; Weiler, A. M.; Friedrich, T. C.; Aliota, M. T.; Mohr, E. L.; Golos, T. G.
10.1101/2023.03.13.532348 — pathology — Posted on 2023-03-14
2670 Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)
Battaglia, R.; Faridounnia, M.; Beltran, A.; Robinson, J.; Kinghorn, K.; Ezzell, J. A.; Bharucha-Goebel, D.; Bonnemann, C.; Hooper, J. E.; Opal, P.; Bouldin, T. W.; Armao, D.; Snider, N.
10.1101/2023.03.13.532440 — cell biology — Posted on 2023-03-14
2672 The maize PLASTID TERMINAL OXIDASE (PTOX) gene controls the carotenoid content of kernels.
Nie, Y.; Wang, H.; Zhang, G.; Ding, H.; Han, B.; Liu, L.; Shi, J.; Du, J.; Li, X.; Li, X.; Zhao, Y.; Zhang, X.; Liu, C.; Weng, J.; Li, X.; Zhang, X.; Zhao, X.; Pan, G.; Jackson, D.; Wu, Q.; Zhang, Z.
10.1101/2023.03.13.532334 — plant biology — Posted on 2023-03-14
2675 Interpretation of body condition index should be informed by natural history
Wishart, A. E.; Guerrero-Chacon, A. L.; Smith, R.; Hawkshaw, D. M.; McAdam, A. G.; Dantzer, B.; Boutin, S.; Lane, J.
10.1101/2023.01.31.524791 — physiology — Posted on 2023-03-14
2676 Involvement of an IgE/Mast cell/B cell amplification loop in abdominal aortic aneurysm progression
Loste, A.; Clement, M.; Delbosc, S.; Guedj, K.; Senemaud, J.; Gaston, A.-T.; Morvan, M.; Even, G.; Gautier, G.; Eggel, A.; Arock, M.; Procopio, E.; Deschildre, C.; Louedec, L.; Michel, J.-B.; Deschamps, L.; Castier, Y.; Coscas, R.; Alsac, J.-M.; Launay, P.; Caligiuri, G.; Nicoletti, A.; Le Borgne, M.
10.1101/2022.09.13.507783 — pathology — Posted on 2023-03-14
2677 Native extracellular matrix probes to target patient- and tissue- specific cell-microenvironment interactions by force spectroscopy
Holuigue, H.; Nacci, L.; Di Chiaro, P.; Chighizola, M.; Locatelli, I.; Schulte, C.; Alfano, M.; Diaferia, G. R.; Podesta, A.
10.1101/2022.12.02.518867 — biophysics — Posted on 2023-03-14
2679 Mechanism of targeted killing of P. aeruginosa by pyocins SX1 and SX2
Premsuriya, J.; Mosbahi, K.; Atanaskovic, I.; Kleanthous, C.; Walker, D.
10.1101/2022.10.27.514055 — microbiology — Posted on 2023-03-14
2680 Basolateral amygdala astrocytes are engaged by the acquisition and expression of a contextual fear memory
Suthard, R. L.; Senne, R. A.; Buzharsky, M. D.; Pyo, A. Y.; Dorst, K. E.; Diep, A.; Cole, R. H.; Ramirez, S.
10.1101/2022.09.11.507456 — neuroscience — Posted on 2023-03-14
2681 Arabidopsis cell suspension culture and RNA sequencing reveal regulatory networks underlying plant programmed cell death.
Burke, R.; McCabe, A.; Ramesh Sonawane, N.; Hasmukh Rathod, M.; Whelan, C. V.; McCabe, P. F.; Kacprzyk, J.
10.1101/2023.03.14.532467 — plant biology — Posted on 2023-03-14
2683 Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control
Wible, D. J.; Parikh, Z.; Cho, E. J.; Chen, M.-D.; Mukhopadhyay, S.; Dalby, K. N.; Varadarajan, S.; Bratton, S. B.
10.1101/2023.03.13.532495 — cell biology — Posted on 2023-03-14
2685 Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Experimental Glaucoma and Optic Nerve Crush
Keuthan, C. J.; Schaub, J.; Wei, M.; Fang, W.; Quillen, S.; Kimball, E.; Johnson, T. V.; Ji, H.; Zack, D. J.; Quigley, H. A.
10.1101/2023.02.21.529410 — molecular biology — Posted on 2023-03-14
2686 Apicomplexans predict thermal stress mortality in the Mediterranean coral Paramuricea clavata
Bonacolta, A. M.; Miravall, J.; Gomez-Gras, D.; Ledoux, J.-B.; Lopez-Sendino, P.; Garrabou, J.; Massana, R.; del Campo, J.
10.1101/2022.11.23.517658 — microbiology — Posted on 2023-03-14
2689 Neurodesk: An accessible, flexible, and portable data analysis environment for reproducible neuroimaging
Renton, A. I.; Dao, T. T.; Abbott, D. F.; Amos, T. J.; Bollmann, S.; Botting, A.; Campbell, M. E. J.; Chang, J.; Civier, O.; Close, T. G.; Eckstein, K.; Egan, G. F.; Evas, S.; Flandin, G.; Garner, K. G.; Garrido, M. I.; Ghosh, S. S.; Grignard, M.; Hannan, A. J.; Huber, R.; Hughes, M. E.; Johnstone, T.; Kaczmarzyk, J. R.; Kasper, L.; Kuhlmann, L.; Lou, K.; Lyons, P.; Mantilla-Ramos, Y.-J.; Mattingley, J. B.; Morris, J.; Narayanan, A.; Pestilli, F.; Puce, A.; Ribeiro, F. L.; Rogasch, N. C.; Rorden, C.; Schira, M.; Shaw, T. B.; Slade, B. M.; Spitz, G.; Stewart, A.; Sullivan, R. P.; White, D. J.;
10.1101/2022.12.23.521691 — neuroscience — Posted on 2023-03-14
2693 The black goby Gobius niger Linnaeus, 1758 in the Marchica lagoon (Alboran Sea, Morocco): Spatial-temporal distribution and its environmental drivers, and the site-related footprint
Lamkhalkhal, A.; Selfati, M.; Rahmouni, I.; Kaddouri, N.; Badaoui, B.; Pariselle, A.; Benhoussa, A.; Kovacic, M.; Kmentova, N.; Vanhove, M. P. M.; Bazairi, H.
10.1101/2022.10.02.510494 — ecology — Posted on 2023-03-14
2696 Single-cell perspectives on the function and development of deep-sea mussel bacteriocytes
Chen, H.; Li, M.; Wang, M.; Zhong, Z.; Lian, C.; Zhou, L.; Zhang, H.; Wang, H.; Cao, L.; Li, C.
10.1101/2022.05.28.493830 — molecular biology — Posted on 2023-03-14
2697 White matter network organization predicts memory decline after epilepsy surgery
Stasenko, A.; Kaestner, E.; Arienzo, D.; Schadler, A.; Helm, J. L.; Shih, J.; Ben-Haim, S.; McDonald, C. R.
10.1101/2023.01.14.524071 — neuroscience — Posted on 2023-03-14
2699 The contribution of Neanderthal introgression and natural selection to neurodegenerative diseases
Chen, Z.; Reynolds, R. H.; Pardinas, A. F.; Gagliano Taliun, S. A.; van Rheenen, W.; Lin, K.; Shatunov, A.; Gustavsson, E. K.; Fogh, I.; Jones, A. R.; Robberecht, W.; Corcia, P.; Chio, A.; Shaw, P.; Morrison, K. E.; Veldink, J.; van den Berg, L. H.; Shaw, C. E.; Powell, J. F.; Silani, V.; Hardy, J.; Houlden, H.; Owen, M. J.; Turner, M.; Ryten, M.; Al-Chalabi, A.
10.1101/2022.04.29.490053 — neuroscience — Posted on 2023-03-14
2701 Measuring single-cell susceptibility to antibiotics within monoclonal bacterial populations
Le Quellec, L.; Aristov, A.; Guitierrez Ramos, S.; Amselem, G.; Bos, J.; Baharoglu, Z.; Mazel, D.; Baroud, C.
10.1101/2023.03.08.531654 — bioengineering — Posted on 2023-03-14
2702 Switching of RNA splicing regulators in immature neuroblasts: a key step in adult neurogenesis
Bernou, C.; Mouthon, M.-A.; Daynac, M.; Demaille, B.; Barroca, V.; Couillard-Despres, S.; Dechamps, N.; Menard, V.; Bellenger, L.; Antoniewski, C.; Chicheportiche, A.; Boussin, F. D.
10.1101/2023.03.12.532290 — genomics — Posted on 2023-03-14
2703 High-quality haploid genomes corroborate 29 chromosomes and highly conserved synteny of genes in Hyles hawkmoths (Lepidoptera: Sphingidae)
Hundsdoerfer, A. K.; Schell, T.; Patzold, F.; Wright, C.; Yoshido, A.; Marec, F.; Daneck, H.; Winkler, S.; Greve, C.; Podsiadlowski, L.; Hiller, M.; Pippel, M.
10.1101/2022.04.08.487644 — genomics — Posted on 2023-03-14
2704 Genome-wide association studies reveal novel loci controlling tuber flesh color and oxidative browning in Dioscorea alata
Dossa, K.; Morel, A.; Houngbo, M. E.; Mota, A. Z.; Maledon, E.; Irep, J.-L.; Diman, J.-L.; Mournet, P.; Causse, S.; Van, K. N.; Cornet, D.; Chair, H.
10.1101/2023.03.12.532275 — genetics — Posted on 2023-03-14
2705 A Novel HIF-2α/ARNT Signaling Pathway Protects Against Microvascular Dysfunction and heart failure After Myocardial Infarction
Ullah, K.; Ai, L.; Li, Y.; Liu, L.; Zhang, Q.; Pan, K.; Humayun, Z.; Sitikov, A.; Su, Q.; Zhao, Q.; Sharp, W. W.; Fang, Y.; Wu, D.; Liao, J. K.; Wu, R.
10.1101/2023.03.12.532316 — cell biology — Posted on 2023-03-14
2711 A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a non-hemophiliac state
Teranishi-Ikawa, Y.; Soeda, T.; Koga, H.; Yamaguchi, K.; Kato, K.; Esaki, K.; Asanuma, K.; Funaki, M.; Ichiki, M.; Ikuta, Y.; Ito, S.; Joyashiki, E.; Komatsu, S.-I.; Muto, A.; Nishimura, K.; Okuda, M.; Sanada, H.; Sato, M.; Shibahara, N.; Wakabayashi, T.; Yamaguchi, K.; Matsusaki, A.; Sampei, Z.; Shiraiwa, H.; Konishi, H.; Kawabe, Y.; Hattori, K.; Kitazawa, T.; Igawa, T.
10.1101/2022.12.19.520692 — bioengineering — Posted on 2023-03-14
2712 Sulfolactaldehyde dehydrogenase of Rhizobium leguminosarum: Kinetic and structural analysis
Li, J.; Sharma, M.; Meek, R. W.; Alhifthi, A.; Armstrong, Z.; Madiedo Soler, N.; Goddard-Borger, E. D.; Blaza, J. N.; Davies, G. J.; Williams, S. J.
10.1101/2023.03.13.532361 — biochemistry — Posted on 2023-03-14
2714 Mitochondrial translation regulates terminal erythroid differentiation by maintaining iron homeostasis
Morishima, T.; Fakruddin, M.; Masuda, T.; Wang, Y.; Schoonenberg, V. A. C.; Butter, F.; Arima, Y.; Akaike, T.; Tomizawa, K.; Wei, F.; Suda, T.; Takizawa, H.
10.1101/2023.03.05.531223 — cell biology — Posted on 2023-03-14
2715 Potential of Negative Ion Mode Proteomics: MS1-Only Approach
Penanes, P. A.; Gorshkov, V.; Ivanov, M. V.; Gorshkov, M. V.; Kjeldsen, F.
10.1101/2023.03.06.530802 — molecular biology — Posted on 2023-03-14
2716 Increased thermostability of an engineered flavin-containing monooxygenase to remediate trimethylamine in fish protein hydrolysates
Goris, M.; Cea-Rama, I.; Puntervoll, P.; Ree, R.; Almendral, D.; Sanz-Aparicio, J.; Ferrer, M.; Bjerga, G. E. K.
10.1101/2023.03.10.532160 — molecular biology — Posted on 2023-03-14
2717 Metabolic influence of core ciliates within the rumen microbiome
Andersen, T. O.; Altshuler, I.; de Leon, A. V. P.; Walter, J.; McGovern, E.; Keogh, K.; Martin, C.; Bernard, L.; Morgavi, D. P.; Park, T.; Li, Z.; Jiang, Y.; Firkins, J. L.; Yu, Z.; Hvidsten, T. R.; Waters, S. M.; Popova, M.; Arntzen, M.; Hagen, L. H.; Pope, P. B.
10.1101/2022.06.22.497163 — microbiology — Posted on 2023-03-14
2718 Viruses in deep-sea cold seep sediments harbor diverse survival mechanisms and remain genetically conserved within species
Peng, Y.; Lu, Z.; Pan, D.; Shi, L.-D.; Zhao, Z.; Liu, Q.; Zhang, C.; Jia, K.; Li, J.; Hubert, C. R. J.; Dong, X.
10.1101/2023.03.12.532262 — microbiology — Posted on 2023-03-14
2719 An extra-circadian function for human CLOCK in the neocortex
Liu, Y.; Fontenot, M. R.; Kulkarni, A.; Khandelwal, N.; Park, S.-H. E.; Douglas, C.; Harper, M.; Xu, P.; Gupta, N.; Gibson, J. R.; Takahashi, J. S.; Konopka, G.
10.1101/2023.03.13.531623 — neuroscience — Posted on 2023-03-14
2724 A single base pair duplication in SLC33A1 gene causes fetal losses and neonatal lethality in Manech Tete Rousse dairy sheep
Ben Braiek, M.; Szymczak, S.; Andre, C.; Bardou, P.; Fidelle, F.; Plisson-Petit, F.; Sarry, J.; Woloszyn, F.; Moreno-Romieux, C.; Fabre, S.
10.1101/2023.03.13.532360 — genomics — Posted on 2023-03-13
2725 Histone methyltransferase SUV39H1 regulates the Golgi complex via the nuclear envelope-spanning LINC complex
Nishino, M.; Imaizumi, H.; Yokoyama, Y.; Katahira, J.; Kimura, H.; Matsuura, N.; Matsumura, M.
10.1101/2023.03.13.532406 — cell biology — Posted on 2023-03-13
2726 GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage
Vcelkova, T.; Reiter, W.; Zylka, M.; Hollenstein, D. M.; Schuckert, S.; Hartl, M.; Seiser, C.
10.1101/2023.03.13.532402 — molecular biology — Posted on 2023-03-13
2727 An O-GlcNAc transferase pathogenic variant that affects pluripotent stem cell self-renewal
Omelkova, M.; Fenger, C. D.; Murray, M.; Hammer, T. B.; Pravata, V. M.; Bartual, S.; Czajewski, I.; Bayat, A.; Ferenbach, A. T.; Stavridis, M.; van Aalten, D. M. F.
10.1101/2023.03.13.531514 — molecular biology — Posted on 2023-03-13
2728 NHR-23 activity is necessary for C. elegans developmental progression and apical extracellular matrix structure and function
Johnson, L. C.; Vo, A. A.; Clancy, J. C.; Myles, K. M.; Pooranachithra, M.; Aguilera, J. D.; Levenson, M. T.; Wohlenberg, C.; Rechtsteiner, A. D.; Ragle, J. M.; Chisholm, A. D.; Ward, J. D.
10.1101/2021.10.27.465992 — molecular biology — Posted on 2023-03-13
2729 The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation
Khella, M. S.; Schnee, P.; Weirich, S.; Bui, T.; Broehm, A.; Bashtrykov, P.; Pleiss, J.; Jeltsch, A.
10.1101/2023.03.13.532367 — molecular biology — Posted on 2023-03-13
2734 Cancer phylogenetic tree inference at scale from 1000s of single cell genomes
Salehi, S.; Dorri, F.; Chern, K.; Kabeer, F.; Rusk, N.; Funnell, T.; Williams, M. J.; Lai, D.; Andronescu, M.; Campbell, K. R.; McPherson, A.; Aparicio, S.; Roth, A.; Shah, S. P.; Bouchard-Cote, A.
10.1101/2020.05.06.058180 — bioinformatics — Posted on 2023-03-13
2736 Coupling microdroplet-based sample preparation, multiplexed isobaric labeling, and nanoflow peptide fractionation for deep proteome profiling of tissue microenvironment
Velickovic, M.; Fillmore, T. L.; Attah, K.; Posso, C.; Pino, J. C.; Zhao, R.; Williams, S. M.; Velickovic, D.; Jacobs, J. M.; Burnum-Johnson, K. E.; Zhu, Y.; Piehowski, P. D.
10.1101/2023.03.13.531822 — biochemistry — Posted on 2023-03-13
2741 A Dynamic population of prophase CENP-C is required for meiotic chromosome segregation
Fellmeth, J.; Sturm, H.; Jang, J. K.; Changela, N.; Parikh, A.; Persaud, M.; McKim, K. S.
10.1101/2023.03.13.532437 — genetics — Posted on 2023-03-13
2742 Centriole Remodeling Evolved into Centriole Degradation in Mouse Sperm
Khanal, S.; Puente, N.; Chandanayaka, R.; Assefa, K. Y.; Nawras, M.; Turner, K.; Back, E. D.; Royfman, A.; Burkett, J.; Cheong, S. H.; Fisher, H. S.; Sindhwani, P.; Gray, J.; Basappa, R. N.; Avidor-Reiss, T.
10.1101/2023.03.11.532086 — cell biology — Posted on 2023-03-13
2743 Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23
Bloch, Y.; Felix, J.; Merceron, R.; Provost, M.; Symakani, R. A.; De Backer, R.; Lambert, E.; Savvides, S. N.
10.1101/2023.03.13.532366 — molecular biology — Posted on 2023-03-13
2744 Triplet-encoded prebiotic RNA aminoacylation
Su, M.; Schmitt, C.; Liu, Z.; Roberts, S. J.; Liu, K. C.; Roder, K.; Jaschke, A.; Wales, D.; Sutherland, J. D.
10.1101/2023.03.13.532408 — molecular biology — Posted on 2023-03-13
2745 RTF2 controls replication repriming and ribonucleotide excision at the replisome
Conti, B. A.; Ruiz, P. D.; Broton, C.; Blobel, N. J.; Kottemann, M. C.; Sridhar, S.; Lach, F. P.; Wiley, T.; Sasi, N. K.; Carroll, T.; Smogorzewska, A.
10.1101/2023.03.13.532415 — molecular biology — Posted on 2023-03-13
2746 The carboxyl-terminal processing proteases Prc and CtpA modulate cell-surface signalling activity and Pseudomonas aeruginosa virulence
Otero-Asman, J. R.; Sanchez-Jimenez, A.; Bastiaansen, K. C.; Wettstadt, S.; Civantos, C.; Garcia-Puente, A.; Bitter, W.; Llamas, M.
10.1101/2023.03.13.532344 — microbiology — Posted on 2023-03-13
2747 Bacterial contact induces polar plug disintegration to mediate whipworm egg hatching
Robertson, A.; Sall, J.; Venzon, M.; Olivas, J. J.; Zheng, X.; Cammer, M.; Antao, N.; Thur, R. S.; Bethony, J.; Nejsum, P.; Torres, V. J.; Liang, F.-X.; Cadwell, K.
10.1101/2023.03.13.532458 — microbiology — Posted on 2023-03-13
2749 The mechanical arthropod vector Stomoxys calcitrans influences the outcome of lumpy skin disease virus infection in cattle
Cook, C. G.; Munyanduki, H.; Fay, P. C.; Wijesiriwardana, N.; Moffat, K.; Gubbins, S.; Armstrong, S.; Batten, C.; Dietrich, I.; Greaves, D. R.; Darpel, K.; Beard, P. M.
10.1101/2023.03.13.532343 — microbiology — Posted on 2023-03-13
2752 Metabolomics of bacterial-fungal pairwise interactions reveal conserved molecular mechanisms
Luu, G. T.; Little, J. C.; Pierce, E. C.; Morin, M.; Ertekin, C. A.; Wolfe, B. E.; Baars, O.; Dutton, R. J.; Sanchez, L. M.
10.1101/2023.03.13.532449 — microbiology — Posted on 2023-03-13
2753 Sinorhizobium meliloti FcrX coordinates cell cycle and division during free-living growth and symbiosis
Dendene, S.; Xue, S.; Nicoud, Q.; Valette, O.; Frascella, A.; Bonnardel, A.; Le Bars, R.; Bourge, M.; Mergaert, P.; Brilli, M.; Alunni, B.; Bondi, E. G.
10.1101/2023.03.13.532326 — microbiology — Posted on 2023-03-13
2755 Inhibition of type III secretion system induced leukotriene B4 production by Yersinia pestis: A mechanism for early immune evasion
Brady, A.; Pulsifer, A. R.; Price, S. L.; Sheneman, K. R.; Maddipati, K. R.; Bodduluri, S. R.; Pan, J.; Rai, S. N.; Haribabu, B.; Uriarte, S. M.; Lawrenz, M. B.
10.1101/2023.03.13.532349 — microbiology — Posted on 2023-03-13
2756 Epidemiological evaluation and identification of the insect vector of soybean stay-green associated virus
Cheng, R.; Yan, R.; Mei, R.; Wang, Y.; Niu, W.; Ai, H.; Qiao, S.; Xu, M.; Yu, W.; Ye, W.; Wang, Y.; Tao, X.; Zhou, X.; Xu, Y.
10.1101/2023.03.13.532384 — microbiology — Posted on 2023-03-13
2759 Insula dynorphin and kappa opioid receptor systems regulate alcohol drinking in a sex-specific manner in mice
Pina, M.; Pati, D.; Neira, S.; Taxier, L. R.; Stanhope, C.; Mahoney, A.; D'Ambrosio, S.; Kash, T. L.; Navarro, M.
10.1101/2021.11.09.467893 — neuroscience — Posted on 2023-03-13
2762 HSF1 excludes CD8+ T cells from breast tumors via suppression of CCL5
Jacobs, C.; Shah, S.; Lu, W.-C.; Ray, H.; Wang, J.; Sandusky, G.; Nephew, K.; Lu, X.; Cao, S.; Carpenter, R. L.
10.1101/2022.05.12.491688 — cancer biology — Posted on 2023-03-13
2763 Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological features
Rao, S. R.; Verrill, C.; Cerundolo, L.; Alham, N. K.; Kaya, Z.; O'Hanlon, M.; Hayes, A.; Lambert, A.; James, M.; Tullis, I. D. C.; Niederer, J.; Lovell, S.; Omer, A.; Lopez, F.; Leslie, T.; Buffa, F. M.; Bryant, R. J.; Lamb, A. D.; Vojnovic, B.; Wedge, D. C.; Mills, I. G.; Woodcock, D. J.; Tomlinson, I. P. M.; Hamdy, F. C.
10.1101/2023.02.27.530113 — cancer biology — Posted on 2023-03-13
2769 Imaging of plant calcium-sensor kinase conformation monitors real time calcium decoding in planta
Liese, A.; Eichstaedt, B.; Lederer, S.; Schulz, P.; Oehlschlaeger, J.; Feijo, J. A.; Schulze, W. X.; Konrad, K. R.; Romeis, T.
10.1101/2023.03.13.532409 — biochemistry — Posted on 2023-03-13
2771 Plant diversity in diet of Costa Rican Primates in contrasting habitats: a meta-analysis
Chaves, O. M.; Morales-Cerdas, V.; Calderon-Quiros, J.; Azofeifa-Rojas, I.; Riba-Hernandez, P.; Solano-Rojas, D.; Chaves-Cordero, C.; Chacon-Madrigal, E.; Melin, A. D.
10.1101/2023.02.02.526906 — animal behavior and cognition — Posted on 2023-03-13
2773 Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments
Musawi, S.; Donnio, L.-M.; Magnani, C.; Binda, O.; Cote, J.; Lomonte, P.; Mari, P.-O.; Giglia-Mari, G.
10.1101/2022.11.04.515196 — molecular biology — Posted on 2023-03-13
2775 Subthalamic neural oscillations reveal no effect of implicit versus explicit facial emotional processing
Duprez, J.; Dondaine, T.; Houvenaghel, J.-F.; Modolo, J.; Haegelen, C.; Robert, G.; Millet, B.; Drapier, D.; Peron, J.; Grandjean, D.; Drapier, S.; Verin, M.; Sauleau, P.
10.1101/2020.10.21.348755 — neuroscience — Posted on 2023-03-13
2780 The FAAH inhibitor URB597 reduces cocaine seeking during conditioned punishment and withdrawal
Alegre-Zurano, L.; Garcia-Baos, A.; Castro-Zavala, A.; Martin-Sanchez, A.; Medrano, M.; Gallego-Landin, I.; Valverde, O.
10.1101/2023.03.13.532386 — neuroscience — Posted on 2023-03-13
2782 Interpretable full-epoch multiclass decoding for M/EEG
Csaky, R.; van Es, M. W. J.; ParkerJones, O.; Woolrich, M. W.
10.1101/2023.03.13.532375 — neuroscience — Posted on 2023-03-13
2790 Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma-derived metabolite cues
Kyle, K. E.; Puckett, S. P.; Caraballo Rodriguez, A. M.; Rivera Chavez, J.; Samples, R. M.; Earp, C. E.; Raja, H. A.; Pearce, C. J.; Ernst, M.; van der Hooft, J. J. J.; Adams, M. E.; Oberlies, N. H.; Dorrestein, P. C.; Klassen, J. L.; Balunas, M. J.
10.1101/2022.11.12.516288 — microbiology — Posted on 2023-03-13
2794 Development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure in animals
Yuan, F.; Chen, C.; Covaleda, L. M.; Martins, M.; Reinhart, J. M.; Sullivan, D. R.; Diel, D.; Fang, Y.
10.1101/2023.03.11.532204 — microbiology — Posted on 2023-03-13
2795 Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors
Wang, D.-P.; Zhao, R.; Wang, H.-F.; Wang, M.-Y.; Hu, W.-S.; Lin, M.-M.; Shu, W.; Cao, J.-M.; Cui, W.; Zhou, X.
10.1101/2023.03.12.532263 — microbiology — Posted on 2023-03-13
2796 In vitro comparison of SARS-CoV-2 variants
Phadke, K. S.; Higdon, N. B. A.; Bellaire, B. H.
10.1101/2023.03.11.532212 — microbiology — Posted on 2023-03-13
2798 Monoclonal antibodies against human coronavirus NL63 spike
Conlan, M.; Tan, H.-X.; Esterbauer, R.; Kelly, A.; Kent, S. J.; Wheatley, A. K.; Lee, W. S.
10.1101/2023.03.12.532265 — microbiology — Posted on 2023-03-13
2799 Correlating physicochemical and biological properties to define critical quality attributes of a recombinant AAV vaccine candidate
Kumar, P.; Wang, M.; Kumru, O. S.; Hickey, J.; Sanmiguel, J.; Zabaleta, N.; Vandenberghe, L. H.; Joshi, S. B.; Volkin, D. B.
10.1101/2023.03.10.532114 — immunology — Posted on 2023-03-13
2801 Urine proteomic characterization of active and recovered COVID-19 patients
Sun, J.; Wei, J.; Yu, H.; Sun, H.; Liu, X.; Zhang, Y.; Shao, C.; Sun, W.; Gao, Y.
10.1101/2023.03.12.532269 — biochemistry — Posted on 2023-03-13
2802 A malaria parasite phospholipase facilitates efficient asexual blood stage egress
Ramaprasad, A.; Burda, P.-C.; Koussis, K.; Thomas, J. A.; Pietsch, E.; Calvani, E.; Howell, S. A.; MacRae, J. I.; Snijders, A. P.; Gilberger, T. W.; Blackman, M. J.
10.1101/2023.03.13.532312 — microbiology — Posted on 2023-03-13
2803 Alleviating the barrier of adventitious roots formation in recalcitrant mature tissue by slow release of a synthetic auxin
Roth, O.; Yechezkel, S.; Serero, O.; Eliyahu, A.; Vints, I.; Tzeela, P.; Carignano, A.; Janacek, D. P.; Peters, V.; Kessel, A.; Dwivedi, V.; Carmeli-Weissberg, M.; Shaya, F.; Faigenboim-Doron, A.; Riov, J.; Klavins, E.; Dawid, C.; Hammes, U. Z.; Ben-Tal, N.; Napier, R.; Sadot, E.; Weinstain, R.
10.1101/2023.03.13.532257 — plant biology — Posted on 2023-03-13
2808 A Living Organoid Biobank of Crohn's Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics
Tindle, C.; Katkar, G.; Fonseca, A.; Taheri, S.; Lee, J.; Maity, P.; Sayed, I.; Ibeawuchi, S.-R.; Vidales, E.; Pranadinata, R.; Fuller, M.; Stec, D.; Anandachar, M. S.; Perry, K.; Lee, H.; Ear, J.; Boland, B.; Sandborn, W.; Sahoo, D.; Das, S.; Ghosh, P.
10.1101/2023.03.11.532245 — immunology — Posted on 2023-03-13
2809 Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, 4-repeat/full-length tau and alpha-synuclein
Sobek, J.; Li, J.; Combes, B. F.; Gerez, J. A.; Nilsson, P. K.; Henrich, M. T.; Geibl, F. F.; Shi, K.; Rominger, A.; Oertel, W. H.; Nitsch, R. M.; Nordberg, A.; Agren, H.; Riek, R.; Ni, R.
10.1101/2023.03.12.531651 — pharmacology and toxicology — Posted on 2023-03-13
2810 Low-Magnitude Mechanical Signals Combined with Zoledronic Acid Reduce Musculoskeletal Weakness and Adiposity in Estrogen-Deprived Mice
Pagnotti, G. M.; Trivedi, T.; Wright, L. E.; John, S. K.; Murthy, S.; Pattyn, R. R.; Willis, M. S.; She, Y.; Suresh, S.; Thompson, W. R.; Rubin, C. T.; Mohammad, K. S.; Guise, T. A.
10.1101/2023.03.12.531571 — cancer biology — Posted on 2023-03-13
2816 Length estimation of fish detected as non-occluded using a smartphone application and deep learning techniques
Shibata, Y.; Iwahara, Y.; Manano, M.; Kanaya, A.; Sone, R.; Tamura, S.; Kakuta, N.; Nishino, T.; Ishihara, A.; Kugai, S.
10.1101/2023.03.12.532319 — ecology — Posted on 2023-03-13
2819 A high-resolution view of RNA endonuclease cleavage in Bacillus subtilis
Taggart, J.; Lalanne, J.-B.; Durand, S.; Braun, F.; Condon, C.; Li, G.-W.
10.1101/2023.03.12.532304 — molecular biology — Posted on 2023-03-13
2820 Connectome-constrained deep mechanistic networks predict neural responses across the fly visual system at single-neuron resolution
Lappalainen, J. K.; Tschopp, F. D.; Prakhya, S.; McGill, M.; Nern, A.; Shinomiya, K.; Takemura, S.-y.; Gruntman, E.; Macke, J. H.; Turaga, S. C.
10.1101/2023.03.11.532232 — neuroscience — Posted on 2023-03-13
2824 Optimizing Short-format Training: an International Consensus on Effective, Inclusive, and Career-spanning Professional Development in the Life Sciences and Beyond
Williams, J. J.; Tractenberg, R. E.; Batut, B.; Becker, E. A.; Brown, A. M.; Burke, M. L.; Busby, B.; Cooch, N. K.; Dillman, A. A.; Donovan, S. S.; Doyle, M. A.; van Gelder, C. W. G.; Hall, C. R.; Hertweck, K. L.; Jordan, K. L.; Jungck, J. R.; Latour, A. R.; Lindvall, J. M.; Lloret-Llinares, M.; McDowell, G. S.; Morris, R.; Mourad, T.; Nisselle, A.; Ordonez, P.; Paladin, L.; Palagi, P. M.; Sukhai, M. A.; Teal, T. K.; Woodley, L.
10.1101/2023.03.10.531570 — scientific communication and education — Posted on 2023-03-13
2825 Ship-to-Shore Training for Active Deep-Sea Capacity Development
Barnhill, K. A.; Vinha, B.; Smith, A. J.; de Jonge, D.; Gaurisas, D. Y.; Segura, R. M.; Madureira, P.; Albuquerque, M.; Huvenne, V. A. I.; Orejas, C.; Gunn, V.
10.1101/2023.03.11.531674 — scientific communication and education — Posted on 2023-03-13
2828 Measuring intramolecular connectivity in long RNA molecules using two-dimensional DNA patch-probe arrays
Chiang, T. K.; Kimchi, O.; Dhaliwal, H. K.; Villarreal, D. A.; Vasquez, F. F.; Manoharan, V. N.; Brenner, M. P.; Garmann, R. F.
10.1101/2023.03.12.532302 — biophysics — Posted on 2023-03-13
2836 Unsupervised discovery of family specific vocal usage in the Mongolian gerbil
Peterson, R. E.; Choudhri, A.; MItelut, C.; Tanelus, A.; Capo-Battaglia, A.; Williams, A. H.; Schneider, D. M.; Sanes, D. H.
10.1101/2023.03.11.532197 — animal behavior and cognition — Posted on 2023-03-13
2838 Maximum Mutational Robustness in Genotype-Phenotype Maps Follows a Self-similar Blancmange-like Curve
Mohanty, V.; Greenbury, S. F.; Sarkany, T.; Narayanan, S.; Dingle, K.; Ahnert, S. E.; Louis, A. A.
10.1101/2023.03.11.532236 — evolutionary biology — Posted on 2023-03-13
2842 Extraordinary peptide-binding mode of a songbird MHC class-I molecule suggests mechanism to counter pathogen immune evasion
Eltschkner, S.; Mellinger, S.; Buus, S.; Nielsen, M.; Paulsson, K. M.; Lindkvist-Petersson, K.; Westerdahl, H.
10.1101/2023.03.13.532050 — ecology — Posted on 2023-03-13
2843 Manipulation of the nucleoscaffold potentiates cellular reprogramming kinetics
Yang, B. A.; Monteiro da Rocha, A.; Newton, I.; Shcherbina, A.; Wong, S.-W.; Fraczek, P. M.; Larouche, J. A.; Hiraki, H. L.; Baker, B. M.; Shin, J.-W.; Takayama, S.; Thouless, M. D.; Aguilar, C. A.
10.1101/2023.03.12.532246 — cell biology — Posted on 2023-03-13
2845 CRISPR based programmable RNA editing in primary neurons
Ravichandran, K.; Khargaonkar, T.; Samaddar, S.; Banerjee, S.
10.1101/2023.03.10.532141 — neuroscience — Posted on 2023-03-13
2848 BOLD Moments: modeling short visual events through a video fMRI dataset and metadata
Lahner, B.; Dwivedi, K.; Iamshchinina, P.; Graumann, M.; Lascelles, A.; Roig, G.; Gifford, A. T.; Pan, B.; Jin, S.; Ratan Murty, N. A.; Kay, K.; Oliva, A.; Cichy, R.
10.1101/2023.03.12.530887 — neuroscience — Posted on 2023-03-13
2851 Switch-like Compaction of Poly(ADP-ribose) Upon Cation Binding
Badiee, M.; Kenet, A. L.; Ganser, L. R.; Paul, T.; Myong, S.; Leung, A. K.
10.1101/2023.03.11.531013 — biophysics — Posted on 2023-03-13
2852 MpoxRadar: a worldwide Mpox genomic surveillance dashboard
Nasri, F.; Kongkitimanon, K.; Wittig, A.; Sanchez Cortes, J.; Brinkmann, A.; Nitsche, A.; Schmachtenberg, A.-J.; Renard, B. Y.; Fuchs, S.
10.1101/2023.02.03.526935 — bioinformatics — Posted on 2023-03-13
2853 A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis
Kang, S.-Y.; Kimura, M.; Shrestha, S.; Lewis, P.; Lee, S.; Cai, Y.; Joshi, P.; Acharya, P.; Liu, J.; Yang, Y.; Sanchez, J. G.; Ayyagari, S.; Alsberg, E.; Wells, J.; Takebe, T.; Lee, M.-Y.
10.1101/2023.03.11.532210 — bioengineering — Posted on 2023-03-13
2854 Towards bone-remodeling-on-a-chip: self-assembling 3D osteoblast-osteoclast coculture in a microfluidic chip
Vis, M. A. M.; Zhao, F.; Bodelier, E.; Bood, M.; Bulsink, J.; van Doeselaar, M.; Eslami Amirabadi, H.; Ito, K.; Hofmann, S.
10.1101/2023.03.11.532167 — bioengineering — Posted on 2023-03-13
2855 Geographic distribution of feather δ34S in Europe
Brlik, V.; Prochazka, P.; Bontempo, L.; Camin, F.; Jiguet, F.; Osvath, G.; Wunder, M. B.; Powell, R. L.
10.1101/2023.03.10.532116 — ecology — Posted on 2023-03-13
2856 The cell type composition of the adult mouse brain revealed by single cell and spatial genomics
Langlieb, J.; Sachdev, N.; Balderrama, K.; Nadaf, N.; Raj, M.; Murray, E.; Webber, J.; Vanderburg, C.; Gazestani, V.; Tward, D.; Mezias, C.; Li, X.; Cable, D.; Norton, T.; Mitra, P. P.; Chen, F.; Macosko, E.
10.1101/2023.03.06.531307 — neuroscience — Posted on 2023-03-13
2857 High light can alleviate chilling stress in maize
Cackett, L.; Burnett, A. C.; Royles, J.; Hibberd, J. M.; Kromdijk, J.
10.1101/2023.03.07.531599 — plant biology — Posted on 2023-03-13
2858 MicroCT-based imaging of microvasculature within the bone tissue
Haberthür, D.; Khoma, O.-Z.; Hoessly, T.; Zoni, E.; Kruithof-de Julio, M.; Ryan, S. D.; Grunewald, M.; Bellon, B.; Sandgren, R.; Pippenger, B. E.; Bosshardt, D.; Djonov, V.; Hlushchuk, R.
10.1101/2023.03.08.531678 — physiology — Posted on 2023-03-13
2859 Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition
Berns, H. M.; Watkins-Chow, D. E.; Lu, S.; Louphrasitthiphol, P.; Zhang, T.; Brown, K. M.; Moura-Alves, P.; Goding, C. R.; Pavan, W. J.
10.1101/2023.03.10.532018 — genetics — Posted on 2023-03-13
2860 Tomato geranylgeranyl diphosphate synthase isoform 1 specifically interacts with phytoene synthase isoform 3 to produce strigolactones in tomato roots.
Ezquerro, M.; Li, C.; Barja, M. V.; Burbano, E.; Perez-Perez, J.; Wang, Y.; Dong, L.; Lison, P.; Lopez-Gresa, M. P.; Bouwmeester, H.; Rodriguez-Concepcion, M.
10.1101/2022.11.01.514744 — plant biology — Posted on 2023-03-13
2861 Human outperform mouse Purkinje cells in dendritic complexity and computational capacity
Masoli, S.; Sanchez-Ponce, D.; Vrieler, N.; Abu-Haya, K.; Lerner, V.; Shahar, T.; Nedelescu, H.; Rizza, M. F.; Benavides-Piccione, R.; DeFelipe, J.; Yarom, Y.; Munoz, A.; D'Angelo, E.
10.1101/2023.03.08.531672 — neuroscience — Posted on 2023-03-13
2868 Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase
Scheerer, D.; Adkar, B. V.; Bhattacharyya, S.; Levy, D.; Iljina, M.; Riven, I.; Dym, O.; Haran, G.; Shakhnovich, E.
10.1101/2022.11.21.517316 — biophysics — Posted on 2023-03-13
2870 Cortical changes during the learning of sequences of simultaneous finger presses
Garzon, B.; Helms, G.; Olsson, H.; Brozzoli, C.; Ullen, F.; Diedrichsen, J.; Lovden, M.
10.1101/2023.03.12.532251 — neuroscience — Posted on 2023-03-13
2871 Auditory feedback-independent maintenance of song performance through daily singing in adult songbirds
Mizuguchi, D.; Sanchez-Valpuesta, M.; Kim, Y.; dos Santos, E. B.; Kang, H.; Mori, C.; Wada, K.; Kojima, S.
10.1101/2023.02.22.529516 — animal behavior and cognition — Posted on 2023-03-12
2872 Critical role of PCYT2 in muscle health and aging
Cikes, D.; Elsayad, K.; Sezgin, E.; Koitai, E.; Ferenc, T.; Orthofer, M.; Yarwood, R.; Heinz, L.; Sedlyarov, V.; Darwish-Miranda, N.; Taylor, A.; Grapentine, S.; al-Murshedi, F.; Abot, A.; Weidinger, A.; Kutchukian, C.; Sanchez, C.; Cronin, S. J. F.; Novatchkova, M.; Kavirayani, A.; Schuetz, T.; Haubner, B.; Haas, L.; Hagelkrueys, A.; Jackowski, S.; Kozlov, A.; Jacquemond, V.; Knauf, C.; Superti-Furga, G.; Rullman, E.; Gustafsson, T.; McDermott, J. H.; Lowe, M. P.; Radak, Z.; Chamberlain, J. S.; Bakovic, M.; Banka, S.; Penninger, J.
10.1101/2022.03.02.482658 — genetics — Posted on 2023-03-12
2873 Neural dynamics in the limbic system during male social behaviors
Guo, Z.; Yin, L.; Osakada, T.; Lischinsky, J. E.; Chien, J.; Dai, B.; Urtecho, A.; Tong, X.; Chen, Z. S.; Lin, D.
10.1101/2023.03.12.532199 — neuroscience — Posted on 2023-03-13
2876 Batch Effects are Causal Effects: Applications in Human Connectomics
Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Xu, T.; Milham, M.; Caffo, B.; Vogelstein, J. T.
10.1101/2021.09.03.458920 — neuroscience — Posted on 2023-03-12
2878 Whitefly effector G4 interacts with tomato proteins of which MIPDB141 affects whitefly performance
Naalden, D.; Dermauw, W.; Ilias, A.; Baggerman, G.; Mastop, M.; Dangol, S.; Gaertner, N.; Roseboom, W.; Kwaaitaal, M.; Kramer, G.; van den Burg, H. A.; Vontas, J. A.; Van Leeuwen, T.; Kant, M. R.; Schuurink, R.
10.1101/2023.03.11.532171 — plant biology — Posted on 2023-03-12
2879 Finite Sample Adjustments for Average Equivalence Testing
Boulaguiem, Y.; Quartier, J.; Lapteva, M.; Kalia, Y. N.; Victoria-Feser, M.-P.; Guerrier, S.; Couturier, D.-L.
10.1101/2023.03.11.532179 — pharmacology and toxicology — Posted on 2023-03-12
2885 Brain fingerprinting using EEG graph inference
Miri, M.; Abootalebi, V.; Amico, E.; Saeedi-Sourck, H.; Van De Ville, D.; Behjat, H.
10.1101/2023.03.11.532201 — neuroscience — Posted on 2023-03-12
2888 Dual role of CASP8AP2/FLASH in regulating epithelial-to-mesenchymal (EMT) plasticity
Catalanotto, M.; Vaz, J. M.; Abshire, C.; Youngblood, R.; Chu, M.; Levine, H.; Jolly, M. K.; Dragoi, A.-M.
10.1101/2023.03.12.532282 — cancer biology — Posted on 2023-03-12
2890 Phase separation and molecular ordering of the prion-like domain of the thermosensory protein EARLY FLOWERING 3
Hutin, S.; Kumita, J. R.; Strotmann, V. I.; Dolata, A.; Ling, W. L.; Louafi, N.; Popov, A.; Milhiet, P.-E.; Blackledge, M.; Nanao, M. H.; Wigge, P. A.; Stahl, Y.; Costa, L.; Tully, M. D.; Zubieta, C.
10.1101/2023.03.12.532276 — biophysics — Posted on 2023-03-12
2894 Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
Vande Voorde, J.; Najumudeen, A. K.; Steven, R. T.; Nikula, C. J.; Dexter, A.; Zeiger, L. B.; Elia, E. A.; Nassif, A.; Gonzalez-Fernandez, A.; Murta, T.; Gillespie, M.; Ford, C. A.; Lannagan, T. R. M.; Vlahov, N.; Ridgway, R. A.; Nixon, C.; Gilroy, K.; Gay, D. M.; Burton, A.; Yan, B.; Sellers, K.; Wu, V.; Xiang, Y.; Shokry, E.; Clark, W.; Li, V. S. W.; Barry, S. T.; Goodwin, R. J. A.; Takats, Z.; Maddocks, O. D. K.; Sumpton, D.; Yuneva, M. O.; Campbell, A. D.; Bunch, J.; Sansom, O. J.
10.1101/2023.03.12.531945 — cancer biology — Posted on 2023-03-12
2895 Identification of novel oncogenic transcriptional targets of mutant p53 in Esophageal Squamous Cell Carcinoma
George, S. A.; Kotapalli, V.; Ramaswamy, P.; Kumar, R.; Gowrishankar, S.; Uppin, S. G.; Bashyam, M. D.
10.1101/2023.03.12.532255 — cancer biology — Posted on 2023-03-12
2896 Direct determination of oligomeric organization of integral membrane proteins and lipids from intact customizable bilayer
Panda, A.; Giska, F.; Duncan, A. L.; Welch, A. J.; Brown, C.; McAllister, R.; Parameswaran, H.; Goder, J. N. D.; Coleman, J.; Ramakrishnan, S.; Pincet, F.; Guan, L.; Krishnakumar, S.; Rothman, J. E.; Gupta, K.
10.1101/2023.03.12.532274 — biophysics — Posted on 2023-03-12
2897 Antibody targeting of aging damaged isoDGR-protein doubles lifespan in a mouse model of chronic inflammation
Kalailingam, P.; Mohd-Kahliab, K.-H.; Ngan, S. C.; Iyappan, R.; Melekh, E.; Lu, T.; Zien, G. W.; Sharma, B.; Guo, T.; MacNeil, A. J.; Macpherson, R. E. K.; Tsiani, E. L.; O'Leary, D. D.; Lim, K. L.; Su, I. H.; Gao, Y.-G.; Richard, A. M.; Kalaria, R. N.; Chen, C. P.; McCarthy, N. E. K.; Sze, S. K.
10.1101/2023.03.11.532237 — biochemistry — Posted on 2023-03-12
2899 Reconstituting spore cortex peptidoglycan biosynthesis reveals a deacetylase that catalyzes transamidation
Tobin, M. J.; Cho, S. Y.; Profy, W.; Ryan, T. M.; Le, D. H.; Lin, C.; Yip, E. Z.; Dorsey, J. L.; Levy, B. R.; Rhodes, J. D.; Welsh, M. A.
10.1101/2023.03.12.532300 — biochemistry — Posted on 2023-03-12
2903 Parallel and divergent morphological adaptations underlying the evolution of jumping ability in ants
Aibekova, L.; Keller, R. A.; Katzke, J.; Allman, D. M.; Hita Garcia, F.; Labonte, D.; Narendra, A.; Economo, E. P.
10.1101/2023.03.11.531676 — evolutionary biology — Posted on 2023-03-12
2904 Modulating Nucleic Acid Phase Transitions as a Mechanism of Action for Cell-Penetrating Antimicrobial Peptides
Sneideris, T.; Erkamp, N. A.; Ausserwoger, H.; Saar, K. L.; Welsh, T. J.; Qian, D.; Johncock, M. L. L. Y.; Krainer, G.; Borodavka, A.; Knowles, T. P. J.
10.1101/2023.03.11.532143 — microbiology — Posted on 2023-03-12
2905 Viruses in deep-sea cold seep sediments harbor diverse survival mechanisms and remain genetically conserved within species
Peng, Y.; Lu, Z.; Pan, D.; Shi, L.-D.; Zhao, Z.; Liu, Q.; Zhang, C.; Jia, K.; Li, J.; Hubert, C. R. J.; Dong, X.
10.1101/2023.03.12.532262 — microbiology — Posted on 2023-03-12
2907 IL-15 promotes inflammatory Th17 cells in the intestine
Golob, J. L.; Hou, G.; Lee, A.; Grasberger, H.; Berinstein, E.; Zaatari, M. E.; Khaykin, V.; Berinstein, J.; Fry, C.; Nemzek, J.; Kamada, N.; Kao, J. Y.; Bishu, S.
10.1101/2023.03.11.532227 — immunology — Posted on 2023-03-12
2909 Dimensionality reduction reveals separate translation and rotation populations in the zebrafish hindbrain
Feierstein, C. E.; de Goeij, M. H. M.; Ostrovsky, A. D.; Laborde, A.; Portugues, R.; Orger, M. B.; Machens, C. K.
10.1101/2023.03.12.532285 — neuroscience — Posted on 2023-03-12
2910 Odor-evoked transcriptomics of Aedes aegypti mosquitoes
Mappin, F.; Bellantuono, A. J.; Ebrahimi, B.; DeGennaro, M.
10.1101/2023.03.12.532230 — neuroscience — Posted on 2023-03-12
2911 Cellular dynamics under time-varying conditions
Joshi, K.; Roy, S.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.03.07.531540 — biophysics — Posted on 2023-03-12
2913 A molecular glue approach to control the half-life of CRISPR-based technologies
Sreekanth, V.; Jan, M.; Zhao, K. T.; Lim, D.; Davis, J. R.; McConkey, M.; Kovalcik, V.; Barkal, S.; Law, B. K.; Fife, J.; Tian, R.; Vinyard, M. E.; Becerra, B.; Kampmann, M. E.; Sherwood, R. I.; Pinello, L.; Liu, D. R.; Ebert, B. L.; Choudhary, A.
10.1101/2023.03.12.531757 — bioengineering — Posted on 2023-03-12
2914 Structural basis of GAIN domain autoproteolysis and cleavage-resistance in the adhesion G-protein coupled receptors
Pohl, F.; Seufert, F.; Chung, Y. K.; Volke, D.; Hoffmann, R.; Schoneberg, T.; Langenhan, T.; Hildebrand, P. W.; Strater, N.
10.1101/2023.03.12.532270 — biochemistry — Posted on 2023-03-12
2915 Characterization of adaptation mechanisms in sorghum using a multi-reference back-cross nested association mapping design and envirotyping
Garin, V.; Diallo, C.; Tekete, M. L.; Thera, K.; Guitton, B.; Dagno, K.; Diallo, A. G.; Kouressy, M.; Leiser, W.; Rattunde, F.; Sissoko, I.; Toure, A.; Nebie, B.; Samake, M.; Kholova, J.; Frouin, J.; Pot, D.; Vaksmann, M.; Weltzien, E.; Teme, N.; Rami, J.-F.
10.1101/2023.03.11.532173 — genetics — Posted on 2023-03-12
2916 Characterization of extracellular matrix deposited by segmental trabecular meshwork cells
Raghunathan, V.; Nartey, A.; Dhamodaran, K.; Baidouri, H.; Staverosky, J. A.; Keller, K.; Zientek, K.; Reddu, A.; Acott, T.; Vranka, J. A.
10.1101/2023.03.11.532242 — cell biology — Posted on 2023-03-12
2917 Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis
Wayne, C. R.; Bremner, L. I.; Faust, T. E.; Duran-Laforet, V.; Ampatey, N.; Ho, S. J.; Feinberg, P. A.; Arvanitis, P.; Ciric, B.; Delaney, S. L.; Vargas-Deming, W.; Swedo, S.; Menon, V.; Schafer, D. P.; Cutforth, T.; Agalliu, D.
10.1101/2023.03.10.532135 — neuroscience — Posted on 2023-03-12
2918 Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors
Heiser, C. N.; Simmons, A. J.; Revetta, F.; McKinley, E. T.; Ramirez-Solano, M. A.; Wang, J.; Shao, J.; Ayers, G. D.; Wang, Y.; Glass, S. E.; Kaur, H.; Rolong, A.; Chen, B.; Vega, P. N.; Drewes, J. L.; Saleh, N.; Vandekar, S.; Jones, A. L.; Washington, M. K.; Roland, J. T.; Sears, C. L.; Liu, Q.; Shrubsole, M. J.; Coffey, R. J.; Lau, K. S.
10.1101/2023.03.09.530832 — systems biology — Posted on 2023-03-12
2919 Leukemic stem cells hijack lineage inappropriate signalling pathways to promote their growth
Kellaway, S. G.; Potluri, S.; Keane, P.; Blair, H.; Chin, P. S.; Ptasinska, A.; Worker, A.; Ames, L.; Adamo, A.; Coleman, D. J.; Khan, N.; Assi, S.; Krippner-Heidenreich, A.; Raghavan, M.; Cockerill, P. N.; Heidenreich, O.; Bonifer, C.
10.1101/2023.03.10.532081 — cancer biology — Posted on 2023-03-12
2923 Salactin, a dynamically unstable actin homolog in Haloarchaea
Zheng, J.; Lammers, A.; Mallon, J.; Litschel, T.; Moody, E.; Diaz, D. A. R.; Schmid, A.; Williams, T. A.; Bisson, A.; Garner, E. C.
10.1101/2023.03.09.531933 — microbiology — Posted on 2023-03-12
2926 A transcriptome-based phylogeny of Scarabaeoidea confirms the sister group relationship of dung beetles and phytophagous pleurostict scarabs (Coleoptera)
Dietz, L.; Seidel, M.; Eberle, J.; Misof, B.; Pacheco, T. L.; Podsiadlowski, L.; Ranasinghe, S.; Gunter, N. L.; Niehuis, O.; Mayer, C.; Ahrens, D.
10.1101/2023.03.11.532172 — zoology — Posted on 2023-03-12
2927 Multidimensional proteomics identifies molecular trajectories of cellular aging and rejuvenation
Leutert, M.; Armstrong, J. O.; Ollodart, A. R.; Hess, K. N.; Muir, M.; Rodriguez-Mias, R. A.; Kaeberlein, M.; Dunham, M. J.; Villen, J.
10.1101/2023.03.09.531951 — systems biology — Posted on 2023-03-12
2929 A systematic search for RNA structural switches across the human transcriptome
Khoroshkin, M.; Asarnow, D.; Navickas, A.; Winters, A.; Yu, J.; Zhou, S. K.; Zhou, S.; Palka, C.; Fish, L.; Ansel, K. M.; Cheng, Y.; Gilbert, L. A.; Goodarzi, H.
10.1101/2023.03.11.532161 — systems biology — Posted on 2023-03-12
2934 Arabidopsis calmodulin-like proteins CML13 and CML14 interact with proteins that have IQ domains
Teresinski, H. J.; Hau, B.; Symonds, K.; Kilburn, R.; Munro, K.; Doner, N.; Mullen, R. T.; Li, V. H.; Snedden, W. A.
10.1101/2023.03.09.531943 — plant biology — Posted on 2023-03-12
2936 Altered cell wall hydroxycinnamate composition impacts leaf and canopy-level CO2-uptake and water-use in rice
Pathare, V. S.; Panahabadi, R.; Sonawane, B. V.; Apalla, A. J.; Koteyeva, N.; Bartley, L.; Cousins, A. B.
10.1101/2023.03.10.532111 — plant biology — Posted on 2023-03-12
2938 Loss of daylength sensitivity by splice site mutation in Cannabis
Leckie, K. M.; Sawler, J.; Kapos, P.; MacKenzie, J. O.; Giles, I.; Baynes, K.; Lo, J.; Baute, G. J.; Celedon, J. M.
10.1101/2023.03.10.532103 — plant biology — Posted on 2023-03-12
2940 Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells
Fischer, M. A.; Mustafa, A.-H. M.; Hausmann, K.; Ashry, R.; Kansy, A. G.; Liebl, M. C.; Brachetti, C.; Piee-Staffa, A.; Zessin, M.; Ibrahim, H. S.; Hofmann, T. G.; Schutkowski, M.; Sippl, W.; Kramer, O. H.
10.1101/2023.03.09.531973 — pharmacology and toxicology — Posted on 2023-03-12
2944 Phage administration with repeated intravenous doses leads to faster phage clearance in mammalian hosts
Tan, X.; Chen, K.; Jiang, Z.; Liu, Z.; Wang, S.; Yong, Y.; Zhang, J.; Yuan, S.; Huang, Z.; Gao, R.; Zhao, M.; Weng, A.; Yang, Y.; Luo, H.; Zhang, D.; Ma, Y.
10.1101/2023.03.10.532150 — pharmacology and toxicology — Posted on 2023-03-12
2946 Pathology of natural infection with highly pathogenic avian influenza virus (H5N1) clade 2.3.4.4b in wild terrestrial mammals in the United States in 2022
Elsmo, E. J.; Wunschmann, A.; Beckmen, K. B.; Broughton-Neiswanger, L. B.; Buckles, E. L.; Ellis, J.; Fitzgerald, S. D.; Gerlach, R.; Hawkins, S.; Ip, H.; Lankton, J.; Lemley, E. M.; Lenoch, J.; Killian, M. L.; Lantz, K.; Long, L.; Maes, R.; Mainenti, M.; Melotti, J.; Moriarty, M. E.; Nakagun, S.; Ruden, R. M.; Shearn-Bochsler, V.; Thompson, D.; Torchetti, M. K.; Van Wettere, A. J.; Wise, A. G.; Lim, A.
10.1101/2023.03.10.532068 — pathology — Posted on 2023-03-12
2947 Asymmetric oligomerization state and sequence patterning can tune multiphase condensate miscibility
Rana, U.; Xu, K.; Narayanan, A.; Walls, M. T.; Panagiotopoulos, A. Z.; Avalos, J. L.; Brangwynne, C. P.
10.1101/2023.03.11.532188 — biophysics — Posted on 2023-03-12
2950 The GlycoPaSER prototype as a real-time N-glycopeptide identification tool based on the PaSER parallel computing platform
Armony, G.; Brehmer, S.; Srikumar, T.; Pfennig, L.; Zijlstra, F.; Trede, D.; Kruppa, G.; Lefeber, D.; van Gool, A. J.; Wessels, H. J. C. T.
10.1101/2023.03.09.531912 — bioinformatics — Posted on 2023-03-12
2951 Panpipes: a pipeline for multiomic single-cell data analysis.
Rich-Griffin, C.; Curion, F.; Thomas, T.; Agarwal, D.; Theis, F. J.; Dendrou, C.
10.1101/2023.03.11.532085 — bioinformatics — Posted on 2023-03-12
2952 plasma: Partial LeAst Squares for Multiomics Analysis
Yamaguchi, K.; Abdelbaky, S.; Yu, L.; Oakes, C. C.; Coombes, K. R.
10.1101/2023.03.10.532096 — bioinformatics — Posted on 2023-03-12
2955 ZygosityPredictor
Rheinnecker, M.; Froehlich, M.; Ruebsam, M.; Paramasivam, N.; Heilig, C. E.; Froehling, S.; Schlenk, R. F.; Hutter, B.; Huebschmann, D.
10.1101/2023.03.09.531877 — bioinformatics — Posted on 2023-03-12
2958 An efficient error correction and accurate assembly tool for noisy long reads
Hu, J.; Wang, Z.; Sun, Z.; Hu, B.; Ayoola, A. O.; Liang, F.; Li, J.; Sandoval, J. R.; Cooper, D. N.; Ye, K.; Ruan, J.; Xiao, C.-L.; Wang, D.; Wu, D.-D.; Wang, S.
10.1101/2023.03.09.531669 — bioinformatics — Posted on 2023-03-12
2959 Time-Resolved Chemical Phenotyping of Whole Plant Roots with Printed Electrochemical Sensors and Machine Learning
Coatsworth, P.; Cotur, Y.; Naik, A.; Asfour, T.; Silva-Pinto Collins, A.; Olenik, S.; Gonzalez-Macia, L.; Bozkurt, T.; Chao, D.-Y.; Güder, F.
10.1101/2023.03.09.531921 — bioengineering — Posted on 2023-03-12
2961 Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy
McFaline-Figueroa, J. L.; Srivatsan, S.; Hill, A. J.; Gasperini, M.; Jackson, D. L.; Saunders, L.; Domcke, S.; Regalado, S. G.; Lazarchuck, P.; Alvarez, S.; Monnat, R. J.; Shendure, J.; Trapnell, C.
10.1101/2023.03.10.531983 — genomics — Posted on 2023-03-12
2963 Spatial Transcriptomics Arena (STAr): an Integrated Platform for Spatial Transcriptomics Methodology Research
Jiang, X.; Luo, D.; Fernandez, E.; Yang, J.; Li, H.; Jin, K. W.; Zhan, Y.; Yao, B.; Bedi, S.; Xiao, G.; Zhan, X.; Li, Q.; Xie, Y.
10.1101/2023.03.10.532127 — genomics — Posted on 2023-03-12
2964 The inactive X chromosome accumulates widespread epigenetic variability with age
Liu, Y.; Sinke, L.; Jonkman, T.; Slieker, R.; van Zwet, E.; Daxinger, L.; Heijmans, B.
10.1101/2023.03.10.532039 — genetics — Posted on 2023-03-12
2966 Including biotic interactions in species distribution models improves the understanding of species niche: a case of study with the brown bear in Europe
Lucas, P. M.; Thuiller, W.; Talluto, M. V.; Polaina, E.; Albrecht, J.; Selva, N.; De Barba, M.; Maiorano, L.; Penteriani, V.; Guegen, M.; Balkenhol, N.; Dutta, T.; Fedororca, A.; Frank, S. C.; Zedrosser, A.; Afonso-Jordana, I.; Ambarlı, H.; Ballesteros, F.; Bashta, A.-T.; Bilgin, C. C.; Bogdanovic, N.; Bojars, E.; Bojarska, K.; Bragalanti, N.; Broseth, H.; Chynoweth, M. W.; Cirovic, D.; Ciucci, P.; Corradini, A.; De Angelis, D.; de Gabriel Hernando, M.; Domokos, C.; Dutsov, A.; Ertürk, A.; Filacorda, S.; Frangini, L.; Groff, C.; Heikkinen, S.; Hoxha, B.; Huber, D.; Huitu, O.; Ionescu, G.; Ion
10.1101/2023.03.10.532098 — ecology — Posted on 2023-03-12
2967 Morphometric analysis of the terminal ductal lobular unit architecture in human breast
Peurla, M.; Paavolainen, O. K.; Tammelin, E.; Sulander, S.-R.; Mourao, L.; Boström, P.; Brück, N.; Scheele, C. L.; Hartiala, P.; Peuhu, E.
10.1101/2023.03.12.532249 — developmental biology — Posted on 2023-03-12
2968 Pharmacologic Activation of an Integrated Stress Response Kinase Promotes Mitochondrial Remodeling
Perea, V.; Baron, K. R.; Dolina, V.; Aviles, G.; Rosarda, J. D.; Guo, X.; Kampmann, M.; Wiseman, L.
10.1101/2023.03.11.532186 — cell biology — Posted on 2023-03-12
2969 Zebrafish Rif1 impacts zygotic genome activation, replication timing, and sex determination
Masser, E. A.; Noble, T. D.; Siefert, J. C.; Goins, D.; Sansam, C. G.; Sansam, C. L.
10.1101/2022.10.21.512903 — cell biology — Posted on 2023-03-12
2970 Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry
Phulphagar, K.; Ctortecka, C.; Vaca, S.; Klaeger, S.; Verzani, E. K.; Hernandez, G. M.; Udeshi, N.; Clauser, K. R.; Abelin, J.; Carr, S. A.
10.1101/2023.03.10.532106 — immunology — Posted on 2023-03-12
2972 Knockout of αβ but not γδ T cells in chickens is associated with high cytotoxicity and deficiency of regulatory and helper T cells
von Heyl, T.; Klinger, R.; Aumann, D.; Zenner, C.; Alhussien, M.; Schlickenrieder, A.; Lengyel, K.; Vikkula, H.-K.; Mittermair, T.; Sid, H.; Schusser, B.
10.1101/2023.03.10.531286 — immunology — Posted on 2023-03-12
2973 Neuroimmune characterization of optineurin insufficiency mouse model during ageing
Mohovic, N.; Peradinovic, J.; Markovinovic, A.; Cimbro, R.; Minic, Z.; Dominovic, M.; Jakovac, H.; Nimac, J.; Rogelj, B.; Munitic, I.
10.1101/2023.03.09.531905 — immunology — Posted on 2023-03-12
2976 Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation
Mader, M. M.-D.; Napole, A.; Wu, D.; Shibuya, Y.; Scavetti, A.; Foltz, A.; Atkins, M.; Hahn, O.; Yoo, Y.; Danziger, R.; Tan, C.; Wyss-Coray, T.; Stainman, L.; Wernig, M.
10.1101/2023.03.10.532123 — neuroscience — Posted on 2023-03-12
2977 Novel method for collecting hippocampal interstitial fluid extracellular vesicles (EV-ISF) reveals sex-dependent changes in microglial EV proteome in response to Aβ pathology
Pait, M. C.; Kaye, S. D.; Su, Y.; Kumar, A.; Singh, S.; Gironda, S. C.; Vincent, S.; Anwar, M.; Carroll, C. M.; Snipes, J. A.; Lee, J.; Furdui, C. M.; Deep, G.; Macauley, S. L.
10.1101/2023.03.10.532133 — neuroscience — Posted on 2023-03-12
2982 Disequilibrium between BRCA1 and BRCA2 circular and messenger RNAs plays a role in breast cancer
Levacher, C.; Viennot, M.; Drouet, A.; Beaussire, L.; Coutant, S.; Thery, J.-C.; Baert-Desurmont, S.; Lae, M.; Ruminy, P.; Houdayer, C.
10.1101/2023.03.10.532029 — cancer biology — Posted on 2023-03-12
2983 A rapid, multiplex digital PCR assay for EGFR, KRAS, BRAF, ERBB2 variants and ALK, RET, ROS1, NTRK1 gene fusions in non-small cell lung cancer
Leatham, B.; McNall, K.; Subramanian, H. K.; Jacky, L.; Alvarado, J. G.; Yurk, D.; Wang, M.; Green, D. C.; Tsongalis, G. J.; Rajagopal, A.; Schwartz, J.
10.1101/2023.03.09.531949 — cancer biology — Posted on 2023-03-12
2986 Determinants of Disordered Protein Co-Assembly Into Discrete Condensed Phases
Welles, R. M.; Sojitra, K. A.; Garabedian, M. V.; Xia, B.; Regy, R. M.; Gallagher, E. R.; Mittal, J.; Good, M. C.
10.1101/2023.03.10.532134 — biophysics — Posted on 2023-03-12
2987 Impact of Phosphorylation on alpha-Synuclein Structural Determinants
Dorn, A. E.; de Bruyn, E.; Rossetti, G.; Fernandez, C.; Outeiro, T. F.; Schulz, J. B.; Carloni, P.
10.1101/2023.03.10.531864 — biophysics — Posted on 2023-03-12
2988 Impact and characterization of serial structural variations across humans and great apes
Höps, W.; Rausch, T.; Ebert, P.; Human Genome Structural Variation Consortium (HGSVC), ; Korbel, J. O.; Sedlazeck, F.
10.1101/2023.03.09.531868 — bioinformatics — Posted on 2023-03-12
2991 scBubbletree: quantitative visualization of single cell RNA-seq data
Kitanovski, S.; Cao, Y.; Ttoouli, D.; Farahpour, F.; Wang, J.; Hoffmann, D.
10.1101/2023.03.09.531263 — bioinformatics — Posted on 2023-03-12
2992 T-CLEARE: A Pilot Community-Driven Tissue-Clearing Protocol Repository
Weiss, K.; Huisken, J.; Bakalov, V.; Engle, M.; Gridley, L.; Krzyzanowski, M.; Madden, T.; Maiese, D.; Waterfield, J.; Williams, D.; Wu, X.; Hamilton, C. M.; Huggins, W.
10.1101/2023.03.09.531970 — bioinformatics — Posted on 2023-03-12
2994 MetaGut: Insights into gut microbiomes in stem cell transplantation by comprehensive shotgun long-read sequencing
Spohr, P.; Scharf, S. A.; Rommerskirchen, A.; Henrich, B.; Jaeger, P.; Klau, G. W.; Haas, R.; Dilthey, A. T.; Pfeffer, K.
10.1101/2023.03.10.531901 — bioinformatics — Posted on 2023-03-12
2999 Nondestructive Spatial Lipidomics for Glioma Classification
Martella, D. A.; Rose, L. A.; Rouatbi, N.; Gu, C.; Caprettini, V.; Jensen, M.; Hagemann, C.; Serio, A.; Al-Jamal, K.; Parsons, M.; Bergholt, M.; Brennan, P.; Zaritski, A.; Chiappini, C.
10.1101/2023.03.09.531882 — bioengineering — Posted on 2023-03-12
3000 Facilitating Electrochemical Lateral Flow Assay using NFC-Enabled Potentiostat and Nitrocellulose-based Metal Electrodes
Gonzalez-Macia, L.; Li, Y.; Zhang, K.; Nunez-Bajo, E.; Barandun, G.; Cotur, Y.; Asfour, T.; Olenik, S.; Coatsworth, P.; Herrington, J.; Güder, F.
10.1101/2023.03.09.531916 — bioengineering — Posted on 2023-03-12
3002 Signature reversion of three disease-associated gene signatures prioritizes cancer drug repurposing candidates
Fisher, J. L.; Wilk, E. J.; Oza, V. H.; Howton, T. C.; Flanary, V. L.; Clark, A. D.; Hjelmeland, A. B.; Lasseigne, B. N.
10.1101/2023.03.10.532074 — genomics — Posted on 2023-03-12
3004 Generating high quality reference genomes from field collected specimens by optimizing preservation
Minich, J. J.; Moore, M. L.; Allsing, N. A.; Murray, E. R.; Tran, L.; Michael, T. P.
10.1101/2023.03.10.532097 — genomics — Posted on 2023-03-12
3006 Epigenetic then genetic variations underpin rapid adaptation of oyster populations (Crassostrea gigas) to Pacific Oyster Mortality Syndrome (POMS)
Gawra, J.; Valdivieso, A.; Roux, F.; Laporte, M.; de Lorgeril, J.; Gueguen, Y.; Saccas, M.; Escoubas, J.-M.; Montagnani, C.; Destoumieux-Garzon, D.; Lagarde, F.; Leroy, M.; Haffner, P.; Petton, B.; Cosseau, C.; Morga, B.; Degremont, L.; Mitta, G.; Grunau, C.; Vidal-Dupiol, J.
10.1101/2023.03.09.531494 — evolutionary biology — Posted on 2023-03-12
3011 Topography modulates climate sensitivity of multidecadal trends of holm oak decline
Lopez-Ballesteros, A.; Rodriguez-Caballero, E.; Moreno, G.; Escribano, P.; Heres, A. M.; Curiel-Yuste, J.
10.1101/2023.03.09.531879 — ecology — Posted on 2023-03-12
3012 The effects of artificial light at night (ALAN) on the gaping activity and feeding of mussels
Christoforou, E.; Dominoni, D. M.; Lindstrom, J.; Diamantopoulou, C.; Czyzewski, J.; Mirzai, N.; Spatharis, S.
10.1101/2023.03.10.532051 — ecology — Posted on 2023-03-12
3015 A social-ecological geography of southern Canadian Lakes
Dupont, A.; Botrel, M.; Fortin St-Gelais, N.; Poisot, T.; Maranger, R.
10.1101/2023.03.09.531893 — ecology — Posted on 2023-03-12
3016 Influence of visual perception on movement decisions by an ungulate prey species
Newman, B. A.; Dyal, J. R.; Miller, K. V.; Cherry, M. J.; D'Angelo, G. J.
10.1101/2023.03.10.532105 — ecology — Posted on 2023-03-12
3018 Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure with Pulmonary Hypertension
Jani, V.; Aslam, M. I.; Fenwick, A. J.; Ma, W.; Gong, H.; Milburn, G.; Nissen, D.; Cubero Salazar, I. M.; Hanselman, O.; Mukherjee, M.; Halushka, M. K.; Margulies, K. B.; Campbell, K.; Irving, T. C.; Kass, D. A.; Hsu, S.
10.1101/2023.03.09.531988 — biophysics — Posted on 2023-03-12
3019 Correlation of blood TCR repertoire with an organ manifestation in a mouse model of autoimmune disease
Ishikawa, T.; Horie, K.; Takakura, Y.; Ohki, H.; Maruyama, Y.; Hayama, M.; Miyauchi, M.; Miyao, T.; Akiyama, N.; Akiyama, T.
10.1101/2023.03.08.531799 — immunology — Posted on 2023-03-12
3022 Comparative assessment of mosquito size and receptiveness to P. falciparum infection of two rearing procedures for Anopheles mosquitoes
Graumans, W.; Lanke, K.; van de Vegte-Bolmer, M.; Stoter, R.; Costa, G. S. P.; Levashina, E. A.; Yang, A. S. P.; Gemert, G.-J. v.; Bousema, T.
10.1101/2023.03.09.531859 — systems biology — Posted on 2023-03-12
3023 Effectiveness of heat tolerance rice cultivars in preserving grain appearance quality under high temperatures - A meta-analysis
Wakatsuki, H.; Takimoto, T.; Ishigooka, Y.; Nishimori, M.; Sakata, M.; Saida, N.; Akagi, K.; Makowski, D.; Hasegawa, T.
10.1101/2023.03.09.531821 — plant biology — Posted on 2023-03-12
3026 Optical coherence tomography of human fetal membrane sub-layers during dynamic loading
Samimi, K.; Contreras Guzman, E.; Wu, M.; Carlson, L.; Feltovich, H.; Hall, T. J.; Myers, K. M.; Oyen, M. L.; Skala, M. C.
10.1101/2023.03.09.531932 — biophysics — Posted on 2023-03-12
3029 Fast alignment of mass spectra in large proteomics datasets, capturing dissimilarities arising from multiple complex modifications of peptides
Prunier, G.; Cherkaoui, M.; Lysiak, A.; Langella, O.; Blein-Nicolas, M.; Lollier, V.; Benoist, E.; Jean, G.; Fertin, G.; Rogniaux, H.; Tessier, D.
10.1101/2023.03.09.531667 — bioinformatics — Posted on 2023-03-12
3034 Long-term climatic stability drives accumulation and maintenance of divergent lineages in a temperate biodiversity hotspot
Buckley, S. J.; Brauer, C. J.; Unmack, P. J.; Hammer, M. P.; Adams, M.; Beatty, S. J.; Morgan, D. L.; Beheregaray, L. B.
10.1101/2023.03.08.531828 — evolutionary biology — Posted on 2023-03-12
3036 Stochastic population models to identify optimal and cost-effective harvest strategies for feral pig eradication
Hamnett, P. W.; Saltre, F.; Page, B.; Tarran, M.; Korcz, M.; Fielder, K.; Andrews, L.; Bradshaw, C. J. A.
10.1101/2023.03.08.531659 — ecology — Posted on 2023-03-12
3037 Functional binding of PD1 ligands predicts response to anti-PD1 treatment in cancer patients
Kaufman, B.; Abramov, O.; Yevko, A.; Apple, D.; Shlapobersky, M.; Greenshpan, Y.; Shaco-Levy, R.; Rouvinov, K.; Livoff, A.; Elkabets, M.; Porgador, A.
10.1101/2023.02.09.527671 — immunology — Posted on 2023-03-12
3038 Anti-citrullinated protein antibodies with diverse specificities ameliorate collagen antibody-induced arthritis in a time-dependent manner
Gomez, A. M.; Brewer, R. C.; Moon, J.-S.; Acharya, S.; Kongpachith, S.; Wang, Q.; Jahanbani, S.; Wong, H. H.; Lanz, T. V.; Love, Z. Z.; Min-Oo, G.; Niedziela-Majka, A.; Robinson, W. H.
10.1101/2023.03.08.531560 — immunology — Posted on 2023-03-12
3039 Compartmentalisation proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation
Ayagama, T.; Charles, P. D.; Bose, S. J.; Boland, B.; Priestman, D. A.; Aston, D.; Berridge, G.; Fischer, R.; Cribbs, A. P.; Song, Q.; Mirams, G. R.; Heather, L.; Galione, A.; Herring, N.; Schotten, U.; Capel, R. A.; Platt, F. M.; Kramer, H.; Verheule, S.; Burton, R. A. B.
10.1101/2023.03.10.532119 — molecular biology — Posted on 2023-03-12
3040 Increased thermostability of an engineered flavin-containing monooxygenase to remediate trimethylamine in fish protein hydrolysates
Goris, M.; Cea-Rama, I.; Puntervoll, P.; Ree, R.; Almendral, D.; Sanz-Aparicio, J.; Ferrer, M.; Bjerga, G. E. K.
10.1101/2023.03.10.532160 — molecular biology — Posted on 2023-03-12
3041 Control of neuronal excitation-inhibition balance by BMP-SMAD1 signaling
Okur, Z.; Schlauri, N.; Bitsikas, V.; Panopoulou, M.; Karmakar, K.; Schreiner, D.; Scheiffele, P.
10.1101/2023.03.11.532164 — neuroscience — Posted on 2023-03-12
3045 Itaconate promotes the differentiation of murine stress erythroid progenitors by increasing Nrf2 activity.
Ruan, B.; Chen, Y.; Trimidal, S. G.; Koo, I.; Cai, J.; Mcguigan, J.; Hall, M.; Patterson, A. D.; Prabhu, K. S.; Paulson, R. F.
10.1101/2023.03.11.532211 — developmental biology — Posted on 2023-03-12
3046 Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle
Vegas, A. D.; Madsen, S.; Cooke, K. C.; Carroll, L.; Khor, J. X. Y.; Turner, N.; Lim, X. Y.; Astore, M. A.; Morris, J.; Don, A. S.; Garfield, A.; Zarini, S.; Zemski Berry, K. A.; Ryan, A. P.; Bergman, B. C.; Brozinick, J. T.; James, D. E.; Burchfield, J. G.
10.1101/2023.03.10.532020 — cell biology — Posted on 2023-03-12
3047 A deep population reference panel of tandem repeat variation
Ziaei Jam, H.; Li, Y.; DeVito, R.; Mousavi, N.; Ma, N.; Lujumba, I.; Adam, Y.; Maksimov, M.; Huang, B.; Dolzhenko, E.; Qiu, Y.; Kakembo, F. E.; Joseph, H.; Onyido, B.; Adeyemi, J.; Bakhtiari, M.; Park, J.; Javadzadeh, S.; Jjingo, D.; Adebiyi, E.; Bafna, V.; Gymrek, M.
10.1101/2023.03.09.531600 — genomics — Posted on 2023-03-12
3051 Hsc70-4 mediates internalization of environmental dsRNA at the surface of Drosophila S2 cells
Fletcher, S. J.; Tome-Poderti, L.; Mongelli, V.; Frangeul, L.; Blanc, H.; Verdier, Y.; Vinh, J.; Saleh, M.-C.
10.1101/2023.03.11.532206 — cell biology — Posted on 2023-03-11
3056 Establishment and characterization of a new Pseudomonas aeruginosa infection model using 2D airway organoids and dual RNA sequencing
Pleguezuelos-Manzano, C.; Beenker, W. A.; van Son, G. J. F.; Beghtel, H.; Amatngalim, G. D.; Beekman, J. M.; Clevers, H.; den Hertog, J.
10.1101/2023.03.11.532178 — microbiology — Posted on 2023-03-11
3057 Mammalian cells internalize bacteriophages and utilize them as a food source to enhance cellular growth and survival
Bichet, M. C.; Adderley, J.; Avellaneda-Franco, L.; Gearing, L. J.; Deffrasnes, C.; David, C.; Pepin, G.; Gantier, M. P.; Lin, R. C.; Patwa, R.; Moseley, G. W.; Doerig, C.; Barr, J. J.
10.1101/2023.03.10.532157 — microbiology — Posted on 2023-03-11
3063 Homozygous haplotype deficiency in Manech Tete Rousse dairy sheep revealed a nonsense variant in MMUT gene affecting newborn lamb viability
Ben Braiek, M.; Moreno-Romieux, C.; Andre, C.; Astruc, J.-M.; Bardou, P.; Bordes, A.; Debat, F.; Fidelle, F.; Hoze, C.; Plisson-Petit, F.; Rivemale, F.; Sarry, J.; Tadi, N.; Woloszyn, F.; FABRE, S.
10.1101/2023.03.10.531894 — genomics — Posted on 2023-03-11
3064 Genetic tracing of the white-bellied pangolins (Phataginus tricuspis) trade in western central Africa
Din Dipita, A.; Missoup, A. D.; Aguillon, S.; Lecompte, E.; Momboua, B.-R.; Chaber, A.-L.; Abernethy, K.; Njiokou, F.; Tindo, M.; Ntie, S.; Gaubert, P.
10.1101/2023.03.10.530129 — genetics — Posted on 2023-03-11
3065 Nitric oxide regulates metabolism in murine stress erythroid progenitors to promote recovery during inflammatory anemia.
Ruan, B.; Trimidal, S. G.; Koo, I.; Qian, F.; Cai, J.; Mcguigan, J.; Hall, M.; Patterson, A. D.; Prabhu, K. S.; Paulson, R. F.
10.1101/2023.03.11.532207 — developmental biology — Posted on 2023-03-11
3068 Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolopyrimidines as Potential Candidates to Treat Human African Trypanosomiasis
Monti, L.; Liu, L. J.; Varricchio, C.; Lucero, B.; Alle, T.; Yang, W.; Bem-Shalom, I.; Gilson, M.; Brunden, K. R.; Brancale, A.; Caffrey, C. R.; Ballatore, C.
10.1101/2023.03.11.532093 — microbiology — Posted on 2023-03-11
3069 Differential contribution of nitrifying prokaryotes to nitrification in groundwater
Krueger, M.; Chaudhari, N.; Thamdrup, B.; Overholt, W.; Bristow, L.; Taubert, M.; Kuesel, K.; Jehmlich, N.; Von Bergen, M.; Herrmann, M.
10.1101/2023.03.10.532121 — microbiology — Posted on 2023-03-11
3071 Intragenic DNA inversions expand bacterial coding capacity
Chanin, R. B.; West, P. T.; Park, R. M.; Wirbel, J.; Green, G. Z. M.; Miklos, A. M.; Gill, M. O.; Hickey, A. S.; Brooks, E. F.; Bhatt, A. S.
10.1101/2023.03.11.532203 — microbiology — Posted on 2023-03-11
3072 Degenerated CRISPRs widely regulate Cas expression to balance immunity and cost
Li, M.; Xiang, H.; Liu, C.; Wang, R.; Li, J.; Cheng, F.; Shu, X.; Zhao, H.; Xue, Q.; Yu, H.; Wu, A.; Wang, L.; Hu, S.; Zhang, Y.; Yang, J.
10.1101/2023.03.10.532045 — microbiology — Posted on 2023-03-11
3073 Characterization of a mouse model of ICF syndrome reveals enhanced CD19 activation in inducing hypogammaglobulinemia
Ying, Z.; Hardikar, S.; Plummer, J. B.; Hamidi, T.; Liu, B.; Chen, Y.; Shen, J.; Mu, Y.; McBride, K. M.; Chen, T.
10.1101/2023.03.09.531982 — immunology — Posted on 2023-03-11
3074 Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity
Ferreira, A. C.; Hemmer, B. M.; Philippi, S. M.; Liu, H.; Zhu, J. D.; Kareva, T.; Ahfeldt, T.; Varghese, M.; Hof, P. R.; Castellano, J. M.
10.1101/2022.12.28.522138 — neuroscience — Posted on 2023-03-11
3076 Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior
Pennington, Z. T.; LaBanca, A. R.; Sompolpong, P.; Christenson Wick, Z.; Feng, Y.; Dong, Z.; Francisco, T. R.; Chen, L.; Fulton, S. L.; Maze, I.; Shuman, T.; Cai, D. J.
10.1101/2023.02.27.530077 — neuroscience — Posted on 2023-03-11
3077 Towards high-performance polyesters from carbon dioxide - novel polyhydroxyarylates from engineered Cupriavidus necator
Averesch, N. J. H.; Pane, V. E.; Kracke, F.; Ziesack, M.; Nangle, S. N.; Waymouth, R. M.; Criddle, C. S.
10.1101/2021.12.12.472320 — synthetic biology — Posted on 2023-03-11
3082 Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway
Zhang, J.; Simpson, C. M.; Berner, J.; Chong, H. B.; Fang, J.; Sahin, Z. O.; Weiss-Sadan, T.; Possemato, A. P.; Harry, S.; Takahashi, M.; Yang, T.-y.; Richter, M.; Patel, H.; Smith, A. E.; Carlin, A. D.; Hubertus de Groot, A. F.; Wolf, K.; Shi, L.; Wei, T.-Y.; Durr, B. R.; Chen, N. J.; Vornbaumen, T.; Wichmann, N. O.; Pooladanda, V.; Matoba, Y.; Kumar, S.; Kim, E.; Bouberhan, S.; Olivia, E.; Rueda, B.; Bardeesy, N.; Liau, B.; Lawrence, M.; Stokes, M. P.; Beausoleil, S. A.; Bar-Peled, L.
10.1101/2023.03.11.532189 — molecular biology — Posted on 2023-03-11
3083 High Resolution Salmonella Subtyping by the MLSTnext Method
Ma, Z.; Gharizadeh, B.; Huang, S.; Jia, M.; Wu, F.; Wang, C.
10.1101/2023.03.10.532158 — microbiology — Posted on 2023-03-11
3084 Development and Evaluation of a Machine Learning Recursive Partitioning Decision Tree Algorithm to Optimize Urinalysis Parameters to Predict Urine Culture Positivity
Seheult, J. N.; Stram, M. N.; Contis, L.; Pontzer, R. E.; Hardy, S.; Baxter, C. M.; Ondras, M.; Wertz, W.; Kip, P. L.; Snyder, G. M.; Pasculle, A. W.
10.1101/2023.03.10.532117 — microbiology — Posted on 2023-03-11
3085 Genomic analysis of cultivated infant microbiomes identifies Bifidobacterium 2'-fucosyllactose utilization can be facilitated by co-existing species
Lou, Y. C.; Rubin, B. E.; Schoelmerich, M. C.; DiMarco, K.; Borges, A. L.; Rovinsky, R.; Song, L.; Doudna, J. A.; Banfield, J. F.
10.1101/2023.03.10.532136 — microbiology — Posted on 2023-03-11
3086 Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome
Ju, X.; Li, S.; Froom, R.; Wang, L.; Lilic, M.; Campbell, E. A.; Rock, J. M.; Liu, S.
10.1101/2023.03.10.532058 — microbiology — Posted on 2023-03-11
3088 Centriole Remodeling Evolved into Centriole Degradation in Mouse Sperm
Khanal, S.; Puente, N.; Chandanayaka, R.; Assefa, K. Y.; Nawras, M.; Turner, K.; Back, E. D.; Royfman, A.; Burkett, J.; Cheong, S. H.; Fisher, H. S.; Sindhwani, P.; Gray, J.; Basappa, R. N.; Avidor-Reiss, T.
10.1101/2023.03.11.532086 — cell biology — Posted on 2023-03-11
3090 Cyclone: an accessible pipeline to analyze, evaluate and optimize multiparametric cytometry data
Patel, R. K.; Jaszczak, R. G.; Kwok, I.; Carey, N. D.; Courau, T.; Bunis, D.; Samad, B.; Avanesyan, L.; Chew, N. W.; Stenske, S.; Jespersen, J. M.; Publicover, J.; Edwards, A.; Naser, M.; Rao, A. A.; Lupin-Jimenez, L.; Krummel, M. F.; Cooper, S.; Baron, J.; Combes, A. J.; Fragiadakis, G. K.
10.1101/2023.03.08.531782 — immunology — Posted on 2023-03-11
3091 Rescuing early Parkinson-induced hyposmia prevents dopaminergic system failure
Pech, U.; Janssens, J.; Schoovaerts, N.; Makhzami, S.; Hulselmans, G.; Poovathingal, S.; Calatayud, C.; Bademosi, A.; Swerts, J.; Geens, A.; Vilain, S. P.; Aerts, S.; Verstreken, P.
10.1101/2023.03.11.532176 — neuroscience — Posted on 2023-03-11
3092 An adaptive behavioral control motif mediated by cortical axo-axonic inhibition
Jung, K.; Chang, M.; Steinecke, A.; Burke, B.; Choi, Y.; Yasuhiro, O.; Fitzpatrick, D.; Taniguchi, H.; Kwon, H.-B.
10.1101/2023.03.10.531767 — neuroscience — Posted on 2023-03-11
3093 The Complexity of Functional Connectivity Profiles of the Subgenual Anterior Cingulate Cortex and Dorsal Lateral Prefrontal Cortex in Major Depressive Disorder: a DIRECT Consortium Study
Chen, X.; Lu, B.; Wang, Y.-W.; Li, X.-Y.; Wang, Z.-H.; Li, H.-X.; Liao, Y.-F.; Blumberger, D. M.; Castellanos, F. X.; Cao, L.-P.; Chen, G.-M.; Chen, J.-S.; Chen, T.; Chen, T.-L.; Cheng, Y.-Q.; Chu, Z.-S.; Cui, S.-X.; Cui, X.-L.; Deng, Z.-Y.; Gong, Q.-Y.; Guo, W.-B.; He, C.-C.; Hu, Z.-J.-Y.; Huang, Q.; Ji, X.-L.; Jia, F.-N.; Kuang, L.; Li, B.-J.; Li, F.; Li, T.; Lian, T.; Liu, X.-Y.; Liu, Y.-S.; Liu, Z.-N.; Long, Y.-C.; Lu, J.-P.; Qiu, J.; Shan, X.-X.; Si, T.-M.; Sun, P.-F.; Wang, C.-Y.; Wang, H.-N.; Wang, X.; Wang, Y.; Wu, X.-P.; Wu, X.-R.; Wu, Y.-K.; Xie, C.-M.; Xie, G.-R.; Xie, P.; Xu, X.-F.
10.1101/2023.03.09.531726 — neuroscience — Posted on 2023-03-11
3094 Natural language processing models reveal neural dynamics of human conversation
Cai, J.; Hadjinicolaou, A. E.; Paulk, A. C.; Williams, Z. M.; Cash, S. S.
10.1101/2023.03.10.531095 — neuroscience — Posted on 2023-03-11
3095 The CRL plastid outer envelope protein supports TOC75-V / OEP80 complex formation in Arabidopsis
Yoshimura, R.; Minamikawa, S.; Suzuki, T.; latrasse, D.; Sicar, S.; Raynaud, C.; Benhamed, M.; Yoshioka, Y.
10.1101/2023.03.07.531578 — plant biology — Posted on 2023-03-11
3096 LRRC8A anion channels modulate vasodilation via association with Myosin Phosphatase Rho Interacting Protein (MPRIP)
Choi, H.; Miller, M. R.; Nguyen, H.-N.; Rohrbough, J. C.; Koch, S. R.; Boatwright, N.; Yarboro, M. T.; Sah, R.; McDonald, H.; Reese, J. J.; Stark, R. J.; Lamb, F. S.
10.1101/2023.03.08.531807 — physiology — Posted on 2023-03-11
3100 Hypertonic lactate infusion reduces vasopressor requirement and biomarkers of brain and cardiac injury after experimental cardiac arrest
Annoni, F.; Su, F.; Peluso, L.; Lisi, I.; Caruso, E.; Pischiutta, F.; Gouvea Bogossian, E.; Garcia, B.; njimi, h.; Vincent, J.-L.; Gaspard, N.; Ferlini, L.; Creteur, J.; Zanier, E. R.; Taccone, F. S.
10.1101/2023.03.07.531627 — neuroscience — Posted on 2023-03-11
3102 Nodule-specific Cu+-chaperone NCC1 is required for symbiotic nitrogen fixation in Medicago truncatula root nodules
Navarro-Gomez, C.; Leon-Mediavilla, J.; Kupper, H.; Rodriguez-Simon, M.; Paganelli-Lopez, A.; Wen, J.; Buren, S.; Mysore, K. S.; Bokhari, S. N. H.; Imperial, J.; Escudero, V.; Gonzalez-Guerrero, M.
10.1101/2023.03.05.531139 — plant biology — Posted on 2023-03-11
3103 Behavioral rhythms are bad predictors of general organismal rhythmicity
Häfker, N. S.; Holcik, L.; Vadiwala, K.; Beets, I.; Mat, A. M.; Stockinger, A. W.; Hammer, S.; Schoofs, L.; Raible, F.; Tessmar-Raible, K.
10.1101/2022.07.16.500291 — animal behavior and cognition — Posted on 2023-03-11
3108 Monosynaptic trans-collicular pathways for sensory-motor integration in the whisker system
Martin-Cortecero, J.; Isaias-Camacho, E. U.; Boztepe, B.; Ziegler, K.; Mease, R. A.; Groh, A.
10.1101/2022.08.30.505868 — neuroscience — Posted on 2023-03-11
3111 2'-Fucosyllactose helps butyrate producers outgrow competitors in the infant gut
Versluis, D. M.; Schoemaker, R.; Looijesteijn, E.; Geurts, J. M. W.; Merks, R. M. H.
10.1101/2023.03.10.532059 — systems biology — Posted on 2023-03-11
3112 RNA allelic frequencies of somatic mutations encode substantial functional information in cancers
Black, J. R. M.; Jones, T. P.; Martinez-Ruiz, C.; Litovchenko, M.; Puttick, C.; McGranahan, N.
10.1101/2023.03.09.531725 — cancer biology — Posted on 2023-03-11
3114 Title: Leveraging Base Pair Mammalian Constraint to Understand Genetic Variation and Human Disease
Sullivan, P. F.; Meadows, J. R. S.; Gazal, S.; Phan, B. N.; Li, X.; Genereux, D. P.; Dong, M. X.; Bianchi, M.; Andrews, G.; Sakthikumar, S.; Nordin, J.; Roy, A.; Christmas, M. J.; Marinescu, V. D.; Wang, C.; Wallerman, O.; Xue, J. R.; Li, Y.; Yao, S.; Sun, Q.; Szatkiewicz, J.; Wen, J.; Huckins, L. M.; Lawler, A. J.; Keough, K. C.; Zheng, Z.; Zeng, J.; Wray, N. R.; Johnson, J.; Chen, J.; Zoonomia Consortium, ; Paten, B.; Reilly, S. K.; Hughes, G. M.; Weng, Z.; Pollard, K. S.; Pfenning, A. R.; Forsberg-Nilsson, K.; Karlsson, E. K.; Lindblad-Toh, K.
10.1101/2023.03.10.531987 — genomics — Posted on 2023-03-10
3115 Molecular cascades and cell-type specific signatures in ASD revealed by single cell genomics
Wamsley, B.; Bicks, L.; Cheng, Y.; Kawaguchi, R.; Quintero, D.; Grundman, J.; Liu, J.; Xiao, S.; Hawken, N.; Margolis, M.; Mazariegos, S.; Geschwind, D. H.
10.1101/2023.03.10.530869 — neuroscience — Posted on 2023-03-10
3118 Genomes of the human filarial parasites Mansonella perstans and Mansonella ozzardi
Sinha, A.; Li, Z.; Poole, C. B.; Morgan, R. D.; Ettwiller, L.; Lima, N. F.; Ferreira, M. U.; Fombad, F. F.; Wanji, S.; Carlow, C. K. S.
10.1101/2023.01.06.523030 — genomics — Posted on 2023-03-10
3120 Mapping of safe and early chemo-attenuated live Plasmodium falciparum immunization identifies immune signature of vaccine efficacy
Borrmann, S.; Sulyok, Z.; Mueller, K.; Fendel, R.; Lamsfus Calle, C.; Sulyok, M.; Friesen, J.; Lalremruata, A.; Sandri, T. L.; Nguyen, T. T.; Knoblich, A.; Sefried, S.; Ibanez, J.; Lorenz, F.-R.; Heimann, H. L.; Weller, D. M.; Steuder, R.; Adukpo, S.; Granados Bayon, P.; Molnar, Z.; Esen, M.; Metzger, W.; James, E. R.; Ruben, A.; Abebe, Y.; Chakravarty, S.; Manoj, A.; KC, N.; Murshedkar, T.; Hafalla, J. C.; Woldearegai, T. G.; O'Rourke, F.; Held, J.; Billingsley, P.; Sim, B. K. L.; Richie, T. L.; Hoffman, S. L.; Kremsner, P.; Matuschewski, K. L.; Mordmueller, B.
10.1101/2020.09.14.296152 — immunology — Posted on 2023-03-10
3122 Modeling naturalistic face processing in humans with deep convolutional neural networks
Jiahui, G.; Feilong, M.; Visconti di Oleggio Castello, M.; Nastase, S. A.; Haxby, J. V.; Gobbini, M. I.
10.1101/2021.11.17.469009 — neuroscience — Posted on 2023-03-10
3124 MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression
Chen, J.; Zheng, Q.; Hicks, J. L.; Trabzonlu, L.; Ozbek, B.; Jones, T.; Vaghasia, A.; Larman, T. C.; Wang, R.; Markowski, M. C.; Denmeade, S. R.; Pienta, K. J.; Hruban, R. H.; Antonarakis, E. S.; Gupta, A.; Dang, C. V.; Yegnasubramanian, S.; De Marzo, A. M.
10.1101/2023.02.20.529259 — cancer biology — Posted on 2023-03-10
3125 A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma
Gureghian, V.; Herbst, H.; Kozar, I.; Mihajlovic, K.; Malod-Dognin, N.; Ceddia, G.; Angeli, C.; Margue, C.; Randic, T.; Philippidou, D.; Tetsi Nomigni, M.; Hemedan, A.; Tranchevent, L.-C.; Longworth, J.; Bauer, M.; Badkas, A.; Gaigneaux, A.; Muller, A.; ostaszewski, M.; Tolle, F.; Przulj, N.; Kreis, S.
10.1101/2023.02.13.528114 — cancer biology — Posted on 2023-03-10
3129 Organisms use mode-switching to solve the explore-vs-exploit problem
Biswas, D.; Lamperski, A.; Yang, Y.; Hoffman, K.; Guckenheimer, J.; Fortune, E. S.; Cowan, N. J.
10.1101/2023.01.11.523566 — animal behavior and cognition — Posted on 2023-03-10
3130 Embracing firefly flash pattern variability with data-driven species classification
Martin, O. L.; Nguyen, C.; Sarfati, R.; Chowdhury, M.; Iuzzolino, M. L.; Nguyen, D. M. T.; Layer, R. M.; Peleg, O.
10.1101/2023.03.08.531653 — ecology — Posted on 2023-03-10
3131 Ontology for Cellular Senescence Mechanisms
Yamagata, Y.; Fukuyama, T.; Onami, S.; Masuya, H.
10.1101/2023.03.09.531883 — cell biology — Posted on 2023-03-10
3136 Strong and localized recurrence controls dimensionality of neural activity across brain areas
Dahmen, D.; Recanatesi, S.; Jia, X.; Ocker, G. K.; Campagnola, L.; Seeman, S.; Jarsky, T.; Helias, M.; Shea-Brown, E.
10.1101/2020.11.02.365072 — neuroscience — Posted on 2023-03-10
3138 Inhibition of muscarinic receptor signaling protects human enteric inhibitory neurons against platin chemotherapy toxicity
Richter, M. N.; Farahvashi, S.; Samuel, R. M.; Majd, H.; Chemel, A. K.; Ramirez, J. T.; Majd, A.; Scantlen, M. D.; Elder, N.; Cesiulis, A.; Garcia, K.; Joshi, T.; Keefe, M. G.; Samiakalantari, B.; Turkalj, E. M.; Yu, J.; Arab, A.; Yin, K.; Culbertson, B.; Vora, B.; Xiong, C.; Kattah, M. G.; Irannejad, R.; Kroetz, D. L.; Nowakowski, T. J.; Goodarzi, H.; Fattahi, F.
10.1101/2023.03.08.531806 — pharmacology and toxicology — Posted on 2023-03-10
3145 YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticles
Cassani, M.; Fernandes, S.; Oliver-De La Cruz, J.; Durikova, H.; Vrbsky, J.; Patocka, M.; Hegrova, V.; Klimovic, S.; Pribyl, J.; Debellis, D.; Skladal, P.; Cavalieri, F.; Caruso, F.; Forte, G.
10.1101/2023.03.10.532035 — bioengineering — Posted on 2023-03-10
3146 Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors
Mobbs, J. I.; Black, K. A.; Tran, M.; Venugopal, H.; Holman, T. R.; Holinstat, M.; Thal, D. M.; Glukhova, A.
10.1101/2023.03.10.532002 — biochemistry — Posted on 2023-03-10
3149 Discovery of 1,3,4-oxadiazoles with slow-action activity against Plasmodium falciparum malaria parasites
Andrews, K. T.; Fisher, G. M.; Firmin, M.; Liepa, A.; Wilson, T.; Gardiner, J.; Mohri, Y.; Rai, A.; Davey, A. K.; Masurier, A.; Delion, A.; Mouratidis, A. A.; Hutt, O.; Burrows, J. N.; Ryan, J. H.; Riches, A.; Skinner-Adams, T. S.
10.1101/2023.03.09.531229 — microbiology — Posted on 2023-03-10
3150 Comparative 3D ultrastructure of Plasmodium falciparum gametocytes
Evers, F.; Roverts, R.; Boshoven, C.; Kea-te Lindert, M.; Sinden, R. E.; Akiva, A.; Kooij, T. W. A.
10.1101/2023.03.10.531920 — microbiology — Posted on 2023-03-10
3154 De novo Design of a Polycarbonate Hydrolase
Holst, L. H.; Madsen, N. G.; Toftgaard, F. T.; Roenne, F.; Moise, I.-M.; Petersen, E. I.; Fojan, P.
10.1101/2023.03.10.532063 — synthetic biology — Posted on 2023-03-10
3156 A high soluble-fibre allele in wheat encodes a defective cell wall peroxidase responsible for dimerization of ferulate moieties on arabinoxylan
Mitchell, R. A. C.; Oszvald, M.; Pellny, T. K.; Freeman, J.; Halsey, K.; Sparks, C. A.; Huttly, A. K.; Specel, S.; Leverington-Waite, M.; Griffiths, S.; Shewry, P. R.; Lovegrove, A.
10.1101/2023.03.08.531735 — plant biology — Posted on 2023-03-10
3158 ATF4 Expression in Thermogenic Adipocytes is Required for Cold-Induced Thermogenesis in Mice via FGF21-Independent Mechanisms
Bjorkman, S. H.; Marti, A.; Jena, J.; Pena, L. M. G.; Weatherford, E. T.; Kato, K.; Koneru, J.; Chen, J. H.; Sood, A.; Potthoff, M. J.; Adams, C. M.; Abel, E. D.; Pereira, R. O.
10.1101/2023.03.09.531964 — physiology — Posted on 2023-03-10
3159 Functional diversity of the TP53 mutome revealed by saturating CRISPR mutagenesis
Funk, J.; Klimovich, M.; Pavlakis, E.; Neumann, M.; Drangenstein, D.; Noeparast, M.; Hunold, P.; Borowek, A.; Balourdas, D.-I.; Kochan, K.; Merle, N.; Bullwinkel, I.; Wanzel, M.; Elmshauser, S.; Nist, A.; Procida, T.; Bartkuhn, M.; Humpert, K.; Mernberger, M.; Savai, R.; Joerger, A. C.; Stiewe, T.
10.1101/2023.03.10.531074 — cancer biology — Posted on 2023-03-10
3161 Clustering predicted structures at the scale of the known protein universe
Barrio-Hernandez, I.; Yeo, J.; Jänes, J.; Wein, T.; Varadi, M.; Velankar, S.; Beltrao, P.; Steinegger, M.
10.1101/2023.03.09.531927 — bioinformatics — Posted on 2023-03-10
3163 Membrane and glycocalyx tethering of DNA nanostructures for enhanced uptake
Wang, W.; Chopra, B.; Walawalkar, V.; Liang, Z.; Adams, R.; Deserno, M.; Ren, X.; Taylor, R.
10.1101/2023.03.09.529286 — bioengineering — Posted on 2023-03-10
3166 Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration
Ramaswami, G.; Yuva-Aydemir, Y.; Akerberg, B.; Matthews, B.; Williams, J.; Golczer, G.; Huang, J.; Huh, D.; Burkly, L. C.; Engle, S. J.; Sehgal, A.; Sigova, A. A.; Fremeau, R. T.; Liu, Y.; Bumcrot, D.
10.1101/2023.03.09.531934 — genomics — Posted on 2023-03-10
3167 Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition
Berns, H. M.; Watkins-Chow, D.; Lu, S.; Louphrasitthiphol, P.; Zhang, T.; Brown, K.; Moura-Alves, P.; Goding, C.; Pavan, W.
10.1101/2023.03.10.532018 — genetics — Posted on 2023-03-10
3170 Ticks; a reservoir for virus emergence at the human-livestock interface in Uganda
Atim, S. A.; Ashraf, S.; Niebel, M.; Ssekagiri, A.; Hardy, M. N.; Shepherd, J. G.; Tong, L.; Ademun, A. R.; Vudriko, P.; Erume, J.; Odongo, S.; Muhanguzi, D.; Nguma, W.; Nakayiki, T.; Namulondo, J.; Filipe, A. D. S.; Lutwama, J. J.; Kaleebu, P.; Masembe, C.; Tweyongyere, R.; Thomson, E. C.
10.1101/2023.03.10.532017 — microbiology — Posted on 2023-03-10
3172 Requirement of GrgA for Chlamydia infectious progeny production
Lu, B.; Wang, Y.; Wurihan, W.; Yeung, S.; Fondell, J.; Wu, X.; Fan, H.
10.1101/2023.03.09.531986 — microbiology — Posted on 2023-03-10
3177 Behavioral, neural and ultrastructural alterations in a graded-dose 6-OHDA mouse model of early-stage Parkinson's disease
Slezia, A.; Hegedus, P.; Rusina, E.; Lengyel, K.; Solari, N.; Kaszas, A.; Balazsfi, D.; Botzanowski, B.; Acerbo, E.; MISSEY, F.; Williamson, A.; Hangya, B.
10.1101/2023.03.08.531684 — neuroscience — Posted on 2023-03-10
3182 Transgenerational effects of exercise on mouse brain and cognition
Cintado, E.; Tezanos, P.; De las Casas, M.; Muela, P.; McGreevy, K. R.; Fontan-Lozano, A.; Sacristan-Horcajada, E.; Pignatelli, J.; de Ceballos, M. L.; del Hierro, M. J.; Fernandez-Punzano, J.; Montoliu, L.; Trejo, J.
10.1101/2023.03.08.531840 — neuroscience — Posted on 2023-03-10
3183 CXCR4 blockade alleviates pulmonary and cardiac outcomes in early COPD
Dupin, I.; Henrot, P.; Maurat, E.; Abohalaka, R.; Chaigne, S.; El Hamrani, D.; Eyraud, E.; Prevel, R.; Esteves, P.; Campagnac, M.; Dubreuil, M.; Cardouat, G.; Bouchet, C.; Ousova, O.; Dupuy, J.-W.; Trian, T.; Thumerel, M.; Begueret, H.; Girodet, P.-O.; Martan, R.; Zysman, M.; Michel, V.; Berger, P.
10.1101/2023.03.10.529743 — pathology — Posted on 2023-03-10
3185 Gene-level alignment of single cell trajectories informs the progression of in vitro T cell differentiation
Sumanaweera, D.; Suo, C.; Muraro, D.; Dann, E.; Polanski, K.; Steemers, A.; Park, J.-E.; Dumitrascu, B.; Teichmann, S.
10.1101/2023.03.08.531713 — bioinformatics — Posted on 2023-03-10
3189 Histone variants shape the chromatin states in Arabidopsis
Jamge, B.; Lorkovic, Z. J.; Axelsson, E.; Osakabe, A.; Shukla, V.; Yelagandula, R.; Akimcheva, S.; Khuen, A. L.; Berger, F.
10.1101/2023.03.08.531698 — genomics — Posted on 2023-03-10
3190 Leaf metabolic traits reveal hidden dimensions of plant form and function
Walker, T. W. N.; Schrodt, F.; Allard, P.-M.; Defossez, E.; Jassey, V. E.; Schuman, M. C.; Alexander, J. M.; Baines, O.; Baldy, V.; Bardgett, R. D.; Capdevila, P.; Coley, P. D.; van Dam, N. M.; David, B.; Descombes, P.; Endara, M.-J.; Fernandez, C.; Forrister, D.; Gargallo-Garriga, A.; Glauser, G.; Marr, S.; Neumann, S.; Pellissier, L.; Peters, K.; Rasmann, S.; Roessner, U.; Salguero-Gomez, R.; Sardans, J.; Weckwerth, W.; Wolfender, J.-L.; Penuelas, J.
10.1101/2023.03.08.531692 — ecology — Posted on 2023-03-10
3191 A new diatom-based multimetric index to assess lake ecological status
Tison-Rosebery, J.; Boutry, S.; Bertrin, V.; Leboucher, T.; Morin, S.
10.1101/2023.03.08.531691 — ecology — Posted on 2023-03-10
3192 Biodiversity shows unique responses to land-use change across regional biomes
Bevan, P. A.; Ferreira, G. B.; Ingram, D. J.; Rowcliffe, M.; Young, L.; Freeman, R.; Jones, K. E.
10.1101/2023.03.08.531730 — ecology — Posted on 2023-03-10
3193 High within-tree leaf trait variation and its response to species diversity and soil nutrients
Davrinche, A.; Bittner, A.; Bruelheide, H.; Albert, G.; Harpole, S.; Haider, S.
10.1101/2023.03.08.531739 — ecology — Posted on 2023-03-10
3194 Salactin, a dynamically unstable actin homolog in Haloarchaea
Zheng, J.; Lammers, A.; Mallon, J.; Litschel, T.; Moody, E.; Diaz, D. A. R.; Schmid, A.; Williams, T. A.; Bisson, A.; Garner, E. C.
10.1101/2023.03.09.531933 — microbiology — Posted on 2023-03-10
3198 Early functional connectivity alterations in contralesional motor networks influence outcome after severe stroke
Braass, H.; Gutgesell, L.; Backhaus, W.; Higgen, F. L.; Quandt, F.; Choe, C.-u.; Gerloff, C.; Schulz, R.
10.1101/2023.03.08.531668 — neuroscience — Posted on 2023-03-10
3200 Aptamer Conformational Dynamics Modulate Neurotransmitter Sensing in Nanopores
Stuber, A.; Douaki, A.; Hengsteler, J.; Buckingham, D.; Momotenko, D.; Garoli, D.; Nakatsuka, N.
10.1101/2023.03.10.532011 — neuroscience — Posted on 2023-03-10
3201 Virtual brain simulations reveal network-specific parameters in neurodegenerative dementias
Monteverdi, A.; Palesi, F.; Schirner, M.; Argentino, F.; Merante, M.; Redolfi, A.; Conca, F.; Mazzocchi, L.; Cappa, S.; Cotta Ramusino, M.; Costa, A.; Pichiecchio, A.; Farina, L.; Jirsa, V.; Ritter, P.; Gandini Wheeler-Kingshott, C.; D'Angelo, E.
10.1101/2023.03.10.532087 — neuroscience — Posted on 2023-03-10
3204 Along-Tract Statistical Mapping of Microstructural Abnormalities in Bipolar Disorder: A Pilot Study
Nabulsi, L.; Chandio, B. Q.; Dhinagar, N.; Laltoo, E.; McPhilemy, G.; Martyn, F. M.; Hallahan, B.; McDonald, C.; Thompson, P. M.; Cannon, D. M.
10.1101/2023.03.07.531585 — neuroscience — Posted on 2023-03-10
3205 Connectional Hierarchy in Human Brain Revealed by Individual Variability of Functional Network Edges
Yang, H.; Wu, G.; Li, Y.; Ma, Y.; Chen, R.; Pines, A.; Xu, T.; Sydnor, V. J.; Satterthwaite, T. D.; Cui, Z.
10.1101/2023.03.08.531800 — neuroscience — Posted on 2023-03-10
3207 Sirtuin3 ensures the metabolic plasticity of neurotransmission during glucose deprivation
Tiwari, A.; Hashemiaghdam, A.; Laramie, M.; Maschi, D.; Haddad, T.; Stunault, M.; Bergom, C.; Javaheri, A.; Klyachko, V.; Ashrafi, G.
10.1101/2023.03.08.531724 — neuroscience — Posted on 2023-03-10
3208 Sex differences in neural representations of social and nonsocial reward in the medial prefrontal cortex.
Isaac, J.; Karkare, S.; Balasubramanian, H.; Schappaugh, N.; Javier, J.; Rashid, M.; Murugan, M.
10.1101/2023.03.09.531947 — neuroscience — Posted on 2023-03-10
3209 Real-time tractography-assisted neuronavigation for TMS
Aydogan, D. B.; Souza, V. H.; Matsuda, R. H.; Lioumis, P.; Ilmoniemi, R. J.
10.1101/2023.03.09.531565 — neuroscience — Posted on 2023-03-10
3211 Branching responses to pruning in cocoa
Tosto, A.; Evers, J. B.; Anten, N. P. R.; Zuidema, P. A.
10.1101/2023.03.08.531700 — plant biology — Posted on 2023-03-10
3213 Destabilization of neuromuscular junctions and deregulation of activity-dependent signalling pathways in Myotonic Dystrophy type I
Falcetta, D.; Quirim, S.; Cocchiararo, I.; Cornut, M.; Theodore, M.; Stiefvater, A.; Lin, S.; Tintignac, L.; Ivanek, R.; Kinter, J.; Ruegg, M. A.; Sinnreich, M.; Castets, P.
10.1101/2023.03.08.531688 — physiology — Posted on 2023-03-10
3214 MicroCT-based imaging of microvasculature within the bone tissue
Haberthur, D.; Khoma, O.-Z.; Hoessly, T.; Zoni, E.; Kruithof-de Julio, M.; Ryan, S. D.; Grunewald, M.; Bellon, B.; Sandgren, R.; Pippenger, B. E.; Bosshardt, D.; Djonov, V.; Hlushchuk, R.
10.1101/2023.03.08.531678 — physiology — Posted on 2023-03-10
3215 Endothelial Histone Deacetylase 1 Activity Impairs Kidney Microvascular NO Signaling in Rats Fed a High Salt Diet
Dunaway, L. S.; Cook, A. K.; Botta, D.; Molina, P. A.; D'Uscio, L. V.; Katusic, Z. S.; Pollock, D. M.; Inscho, E. W.; Pollock, J. S.
10.1101/2023.03.08.531731 — physiology — Posted on 2023-03-10
3217 Sex- and Age-dependent Skin Mechanics - A Detailed Look in Mice
Lin, C.-Y.; Sugerman, G. P.; Kakaletsis, S.; Meador, W. D.; Tepole, A. B.; Rausch, M. K.
10.1101/2023.03.08.531781 — biophysics — Posted on 2023-03-10
3219 Sensitive cluster-free differential expression testing.
Missarova, A.; Rosen, L. U.; Dann, E.; Satija, R.; Marioni, J.
10.1101/2023.03.08.531744 — bioinformatics — Posted on 2023-03-10
3220 LeishMANIAdb: an integrative structural resource of Leishmania proteins
Tusnady, G. E.; Zeke, A.; Kalman, Z. E.; Fatoux, M.; Ricard-Blum, S.; Gibson, T. J.; Dobson, L.
10.1101/2023.03.08.531706 — bioinformatics — Posted on 2023-03-10
3225 Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of heterogeneity on genomic signature scoring
Figiel, S.; Yin, W.; Doultsinos, D.; Erickson, A.; Poulose, N.; Singh, R.; Magnussen, A.; Anbarasan, T.; Teague, R.; He, M.; Lundeberg, J.; Loda, M.; Verrill, C.; Colling, R.; Gill, P. S.; Bryant, R. J.; Hamdy, F. C.; Woodcock, D. J.; Mills, I. G.; Cussenot, O.; Lamb, A. D.
10.1101/2023.03.08.531491 — genomics — Posted on 2023-03-10
3226 The path to "femmes fatales": the evolution of toxin resistance in predatory fireflies.
Yang, L.; Borne, F.; Aardema, M. L.; Zhen, Y.; Peng, J.; Wu, M.; Visconti, R.; Betz, A.; Roland, B. P.; Talsma, A. D.; Palladino, M.; Petschenka, G.; Andolfatto, P.
10.1101/2023.03.08.531760 — evolutionary biology — Posted on 2023-03-10
3230 Sherlock - A flexible, low-resource tool for processing camera-trapping images
Penn, M.; Miles, V.; Astley, K. L.; Ham, C.; Woodroffe, R.; Rowcliffe, M.; Donnelly, C. A.
10.1101/2023.03.08.531714 — ecology — Posted on 2023-03-10
3232 Dynamics of an incoherent feedforward loop drive ERK-dependent pattern formation in the early Drosophila embryo
Ho, E. K.; Oatman, H. R.; McFann, S. E.; Yang, L.; Johnson, H. E.; Shvartsman, S. Y.; Toettcher, J. E.
10.1101/2023.03.09.531972 — developmental biology — Posted on 2023-03-10
3233 Extraocular muscle stem cells exhibit distinct cellular properties associated with non-muscle molecular signatures
Di Girolamo, D.; Benavente-Diaz, M.; Grimaldi, A.; Thomas Lopes, P.; Evano, B.; Gioftsidi, S.; Laville, V.; Mella, S.; Tajbakhsh, S.; Comai, G.
10.1101/2023.03.10.532049 — developmental biology — Posted on 2023-03-10
3235 The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner.
Rangel Rivera, G. O.; Dwyer, C. J.; Knochelmann, H.; Smith, A. S.; Aksoy, B. A.; Cole, A. C.; Wyatt, M. M.; Thaxton, J. E.; Lesinski, G. B.; Paulos, C. M.
10.1101/2023.03.08.531589 — immunology — Posted on 2023-03-10
3236 Individual similarities and differences in eye-movement-related eardrum oscillations (EMREOs)
King, C. D.; Lovich, S. N.; Murphy, D. L. K.; Landrum, R.; Kaylie, D.; Shera, C. A.; Groh, J. M.
10.1101/2023.03.09.531896 — neuroscience — Posted on 2023-03-10
3237 Conserved features of eye movement related eardrum oscillations (EMREOs) across humans and monkeys
Lovich, S. N.; King, C. D.; Murphy, D. L. K.; Abbasi, H.; Bruns, P.; Shera, C. A.; Groh, J. M.
10.1101/2023.03.08.531768 — neuroscience — Posted on 2023-03-10
3243 Concussion-related disruptions to hub connectivity in the default mode network are related to symptoms and cognition
Bouchard, H. C.; Higgins, K. L.; Amadon, G. K.; Laing, J. M.; Maerlender, A.; Al-Momani, S.; Neta, M.; Savage, C. R.; Schultz, D. H.
10.1101/2023.03.07.531551 — neuroscience — Posted on 2023-03-10
3248 Psycho-spatially distinct stressors prompt distinct behavioral strategies through a cell type-specific brain circuit
Ahmadlou, M.; Giannouli, M.; van Vierbergen, J. F. M.; van Leeuwen, T.; Bloem, W.; Houba, J. H. W.; Yasamin Shirazi, M.; Cazemier, J. L.; Dubey, M.; de Winter, F.; Heimel, J. A.
10.1101/2023.03.10.532043 — neuroscience — Posted on 2023-03-10
3253 Exploring the vomeronasal organ in an endangered antelope species
Torres, M. V.; Ortiz-Leal, I.; Ferreiro, A.; Rois, J. L.; Sanchez-Quinteiro, P.
10.1101/2023.03.09.531847 — neuroscience — Posted on 2023-03-10
3254 Memory systems integration in sleep complements rapid systems consolidation in wakefulness
Brodt, S.; Schönauer, M.; Seewald, A.; Beck, J.; Erb, M.; Scheffler, K.; Gais, S.
10.1101/2023.03.09.531360 — neuroscience — Posted on 2023-03-10
3260 An Antibody-Based Molecular Switch for Continuous Biosensing
Thompson, I. A. P.; Saunders, J.; Zheng, L.; Hariri, A. A.; Maganzini, N.; Cartwright, A. P.; Pan, J.; Eisenstein, M.; Soh, H. T.
10.1101/2023.03.07.531602 — bioengineering — Posted on 2023-03-10
3261 Causal Effects of Pupil Size on Visual Processing
Mathot, S.; Berberyan, H.; Buchel, P.; Ruuskanen, V.; Vilotijevic, A.; Kruijne, W.
10.1101/2023.03.08.531702 — animal behavior and cognition — Posted on 2023-03-10
3263 A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability
Fernandez Gallardo, E.; Sifrim, A.; Chappell, J.; Demeulemeester, J.; Herrmann, J. C.; Vermote, R.; Kerremans, A.; Van der Haegen, M.; Van Herck, J.; Vanuytven, S.; Vandereyken, K.; Macaulay, I. C.; Vermeesch, J. R.; Peeraer, K.; Debrock, S.; Pasque, V.; Voet, T.
10.1101/2023.03.08.530586 — developmental biology — Posted on 2023-03-10
3264 β-carotene accelerates resolution of atherosclerosis by promoting regulatory T cell expansion in the atherosclerotic lesion
Pinos, I.; Coronel, J.; Albakri, A.; Blanco, A.; McQueen, P.; Molina, D.; Sim, J.; Fisher, E. A.; Amengual, J.
10.1101/2023.03.07.531563 — immunology — Posted on 2023-03-10
3266 Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans
Kellogg, C. M.; Pham, K.; Machalinski, A. H.; Blankenship, H. E.; Porter, H. L.; Stout, M. B.; Rice, H. C.; Sharpe, A. L.; Beckstead, M. J.; Elliott, A. J. C.; Ocanas, S. R.; Freeman, W. M.
10.1101/2023.03.07.531435 — neuroscience — Posted on 2023-03-10
3269 High light can alleviate chilling stress in maize
Cackett, L.; Burnett, A. C.; Royles, J.; Hibberd, J. M.; Kromdijk, J.
10.1101/2023.03.07.531599 — plant biology — Posted on 2023-03-10
3271 A single C-terminal residue controls SARS-CoV-2 spike trafficking and virion assembly
Dey, D.; Qing, E.; He, Y.; Chen, Y.; Jennings, B.; Cohn, W.; Singh, S.; Gakhar, L.; Schnicker, N. J.; Pierce, B. G.; Whitelegge, J. P.; Doray, B.; Orban, J. P.; Gallagher, T.; Hasan, S. S.
10.1101/2023.03.09.531992 — biophysics — Posted on 2023-03-10
3275 Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike
De Cae, S.; Van Molle, I.; van Schie, L.; Shoemaker, S. R.; Deckers, J.; Debeuf, N.; Lameire, S.; Nerinckx, W.; Roose, K.; Fijalkowska, D.; Devos, S.; Desmet, A.-S.; Zavala Marchan, J. C.; Venneman, T.; Ghassabeh, G. H.; Sedeyn, K.; Ballegeer, M.; Vanheerswynghels, M.; De Wolf, C.; Demol, H.; Vanhaverbeke, P.; Lonigro, C.; Bockstal, V.; Rinaldi, M.; Abdelnabi, R.; Neyts, J.; Marqusee, S.; Lambrecht, B. N.; Callewaert, N.; Remaut, H.; Saelens, X.; Schepens, B.
10.1101/2023.03.10.531533 — microbiology — Posted on 2023-03-10
3276 Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity
Hoving, D.; Marques, A. H. C.; Huisman, W.; Nosoh, B. A.; de Kroon, A. C.; van Hengel, O. R. J.; Wu, B. R.; van Helden, P. M.; Urban, B. C.; Dhar, N.; Ferreira, D. M.; Kwatra, G.; Hokke, C. H.; Jochems, S. P.
10.1101/2023.03.07.531507 — immunology — Posted on 2023-03-10
3277 Adventitial mast cell activation disrupts endothelial cell/pericyte interactions during early life allergic asthma
Joulia, R.; Puttur, F.; Stölting, H.; Entwistle, L. J.; Voitovich, A.; Al-Sahaf, M.; Bonner, K.; Scotney, E.; Molyneaux, P.; Hewitt, R. J.; Walker, S. A.; Yates, L. L.; Saglani, S.; Lloyd, C. M.
10.1101/2023.03.07.529253 — immunology — Posted on 2023-03-10
3278 An atlas of gene regulatory networks for T memory cells in youth and old age
Wayman, J. A.; Thomas, A.; Bejjani, A. T.; Katko, A.; Almanan, M.; Godarova, A.; Korinfskaya, S.; Cazares, T. A.; Yukawa, M.; Kottyan, L. C.; Barski, A.; Chougnet, C. A.; Hildeman, D. A.; Miraldi, E. R.
10.1101/2023.03.07.531590 — immunology — Posted on 2023-03-10
3279 Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease
Ocanas, S. R.; Pham, K. D.; Cox, J. E. J.; Keck, A. W.; Ko, S.; Ampadu, F. A.; Porter, H. L.; Ansere, V. A.; Kulpa, A.; Kellogg, C. M.; Machalinski, A. H.; Chucair-Elliott, A. J.; Freeman, W. M.
10.1101/2023.03.07.531562 — neuroscience — Posted on 2023-03-10
3281 Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus
Iannitelli, A. F.; Segal, A.; Pare, J.-F.; Mulvey, B.; Liles, L. C.; Sloan, S. A.; McCann, K. E.; Dougherty, J. D.; Smith, Y.; Weinshenker, D.
10.1101/2023.03.07.530845 — neuroscience — Posted on 2023-03-10
3282 Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels
Qi, C.; Lavriha, P.; Bayraktar, E.; Vaithia, A.; Schuster, D.; Pannella, M.; Sala, V.; Picotti, P.; Bortolozzi, M.; Korkhov, V. M.
10.1101/2023.03.08.531661 — biophysics — Posted on 2023-03-10
3284 A nanobody-based strategy for rapid and scalable purification of native human protein complexes
Stevens, T. A.; Tomaleri, G. P.; Hazu, M.; Wei, S.; Nguyen, V. N.; DeKalb, C.; Voorhees, R. M.; Pleiner, T.
10.1101/2023.03.09.531980 — biochemistry — Posted on 2023-03-10
3286 Flaviviruses alter endoplasmic reticulum-mitochondria contacts to regulate respiration and apoptosis
Freppel, W.; Anton, A.; Nouhi, Z.; Mazeaud, C.; Gilbert, C.; Tremblay, N.; Barragan Torres, V. A.; Sow, A. A.; Laulhe, X.; Lamarre, A.; Rodrigue-Gervais, I. G.; Pichlmair, A.; Scaturro, P.; Hulea, L.; Chatel-Chaix, L.
10.1101/2023.03.09.531853 — microbiology — Posted on 2023-03-10
3287 Circulation of enterotoxigenic Escherichia coli (ETEC) isolates expressing CS23 from the environment to clinical settings
Calderon Toledo, C.; von Mentzer, A.; Agramont, J.; Thorell, K.; Zhou, Y.; Szabo, M.; Colque-Navarro, P.; Kuhn, I.; Gutierrez-Cortez, S.; Joffre, E.
10.1101/2023.02.08.527665 — microbiology — Posted on 2023-03-10
3288 Further evidences of an emerging stingless bee-yeast symbiosis
de Paula, G. T.; Melo, W. G. P.; de Castro, I.; Menezes, C.; Paludo, C. R.; Rosa, C. A.; Pupo, M. T.
10.1101/2023.03.08.531834 — microbiology — Posted on 2023-03-10
3291 Pectin methylesterification modulates cell wall properties to promote neighbour proximity-induced hypocotyl growth
Senechal, F.; Robinson, S.; Van Schaik, E.; Trevisan, M.; Saxena, P.; Reinhardt, D.; Fankhauser, C.
10.1101/2023.03.07.531598 — plant biology — Posted on 2023-03-10
3292 SARS-CoV-2 variant natural evolution in K18-ACE2 mice increases virulence and produces treatment resistance-linked variant alleles.
Willett, J. D. S.; Gravel, A.; Dubuc, I.; Gudimard, L.; Fortin, P.; Liu, J.-L.; Galvez, J. H.; Zwaig, M.; Roy, A.-M.; Lee, S.; Chen, S.-H.; Ragoussis, I.; Flamand, L.
10.1101/2023.01.16.523994 — genetics — Posted on 2023-03-10
3293 Microsatellites used in forensics are located in regions unusually rich in trait-associated variants
Link, V.; Zavaleta, Y. J. A.; Reyes, R.-J.; Ding, L.; Wang, J.; Rohlfs, R. V.; Edge, M. D.
10.1101/2023.03.07.531629 — genetics — Posted on 2023-03-10
3295 A novel regulatory mechanism of actin cytoskeleton dynamics through a neural microexon in DAAM1 is important for proper memory formation
Polinski, P.; Miret-Cuesta, M.; Zamora-Moratalla, A.; Mantica, F.; Cantero-Recasens, G.; Normanno, D.; Iniguez-Rabago, L.; Morenilla-Palao, C.; Ordono, P.; Bonnal, S.; Gomez-Riera, R.; De Lagran, M. M.; Fernandez-Blanco, A.; Rodriguez-Marin, C.; Permanyer, J.; Folsz, O.; Sierra, C.; Legutko, D.; Wojnacki, J.; Musoles-Lleo, J. L.; Herrera, E.; Dierssen, M.; Irimia, M.
10.1101/2023.01.12.523772 — neuroscience — Posted on 2023-03-10
3296 Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer
Cook, D. P.; Galpin, K. J.; Rodriguez, G. M.; Shakfa, N.; Wilson-Sanchez, J.; Pereira, M.; Matuszewska, K.; Haagsma, J.; Murshed, H.; Cudmore, A. O.; MacDonald, E.; Tone, A.; Shepherd, T. G.; Petrik, J. J.; Koti, M.; Vanderhyden, B. C.
10.1101/2023.03.09.531888 — cancer biology — Posted on 2023-03-10
3299 Tetrapod diversity facets in jeopardy during the Anthropocene
Tordoni, E.; Toussaint, A.; Pärtel, M.; Nogues-Bravo, D.; Theodoridis, S.; Carmona, C. P.
10.1101/2021.07.01.450689 — ecology — Posted on 2023-03-10
3300 Probabilistic inference of epigenetic age acceleration from cellular dynamics
Dabrowski, J. K.; Yang, E. J.; Crofts, S. J. C.; Hillary, R. F.; Simpson, D. J.; Mccartney, D. L.; Marioni, R. E.; Latorre-Crespo, E.; Chandra, T.
10.1101/2023.03.01.530570 — cell biology — Posted on 2023-03-10
3301 Molecular characterization of the N-terminal half of TasA during functional amyloid assembly and its contribution to Bacillus subtilis biofilm formation
Camara-Almiron, J.; Dominguez-Garcia, L.; El Mammeri, N.; Lends, A.; Habestein, B.; de Vicente, A.; Loquet, A.; Romero, D.
10.1101/2023.03.08.531758 — microbiology — Posted on 2023-03-10
3305 Repeats Mimic Pathogen-Associated Patterns Across a Vast Evolutionary Landscape
Sulc, P.; Di Gioacchino, A.; Solovyov, A.; Marhon, S. A.; Sun, S.; Lindholm, H.; Chen, R.; Hosseini, A.; Jiang, H.; Ly, B.-H.; Mehdipour, P.; Abdel-Wahab, O. I.; Vabret, N.; LaCava, J.; De Carvalho, D.; Monasson, R.; Cocco, S.; Greenbaum, B. D.
10.1101/2021.11.04.467016 — systems biology — Posted on 2023-03-10
3307 The Soil Food Web Ontology: aligning trophic groups, processes, and resources to harmonise and automatise soil food web reconstructions
Le Guillarme, N.; Hedde, M.; Potapov, A.; Berg, M. P.; Briones, M. J. I.; Calderon-Sanou, I.; Hohberg, K.; Martinez-Almoyna, C.; Martinez-Munoz, C. A.; Pey, B.; Russell, D.; Thuiller, W.
10.1101/2023.02.03.526812 — ecology — Posted on 2023-03-10
3308 The Loss of the E3 ubiquitin ligase TRIP12 inhibits Pancreatic Acinar Cell Plasticity and Tumor Cell Metastatic Capacity
Brunet, M.; Vargas, C.; Fanjul, M.; Pieruccioni, L.; Varry, D.; Labrousse, G.; Lulka, H.; Capilla, F.; Couvelard, A.; Gigoux, V.; Guillermet-Guibert, J.; Torrisani, J.; Dufresne, M.
10.1101/2023.03.08.531649 — cancer biology — Posted on 2023-03-10
3309 Integrin-alpha V beta 3 is a fundamental factor in medulloblastoma tumorigenicity and radioresistance: A new game for an old player
Echavidre, W.; Durivault, J.; Gotorbe, C.; Blanchard, T.; Pagnuzzi, M.; Vial, V.; Raes, F.; Broisat, A.; Villeneuve, R.; Amblard, R.; Garnier, N.; Ortholan, C.; Faraggi, M.; Serrano, B.; Picco, V.; Montemagno, C.
10.1101/2023.03.08.531652 — cancer biology — Posted on 2023-03-10
3310 A complete digital karyotype of the B-cell leukemia REH cell line resolved by long-read sequencing
Lysenkova Wiklander, M.; Arvidsson, G.; Bunikis, I.; Lundmark, A.; Raine, A.; Marincevic-Zuniga, Y.; Gezelius, H.; Bremer, A.; Feuk, L.; Ameur, A.; Nordlund, J.
10.1101/2023.03.08.531483 — cancer biology — Posted on 2023-03-10
3311 Multi-omics of the gut microbial ecosystem in the immunotherapy resistance in microsatellite instability-high gastrointestinal cancer patients
Cheng, S.; Han, Z.; Yin, X.; Dai, D.; Li, F.; Zhang, X.; Lu, M.; Lu, Z.; Wang, X.; Zhou, J.; Li, J.; Guo, X.; Song, P.; Qiu, C.; Shen, W.; Zhang, Q.; Zhu, N.; Wang, X.; Tan, Y.; Shen, L.; Kou, Y.; Peng, Z.
10.1101/2023.03.07.531467 — cancer biology — Posted on 2023-03-10
3312 Intermittent Fasting induced ketogenesis inhibits mouse epithelial ovarian tumors by promoting anti-tumor T cell response.
Udumula, M. P.; Singh, H.; Faraz, R.; Poisson, L.; Tiwari, N.; Dimitrova, I.; Hijaz, M.; Gogoi, R.; Swenor, M.; Munkarah, A.; Giri, S.; Rattan, R.
10.1101/2023.03.08.531740 — cancer biology — Posted on 2023-03-10
3313 The chromatin reader PHF6 at the crossroad of the replication stress and DNA damage responses in neuroblastoma through interaction with RRM2
Depestel, L.; Sanders, E.; Bekaert, S.-L.; Van Damme, C.; Eggermont, A.; Loontiens, S.; Tilleman, L.; Van Nieuwerburgh, F.; Bek, J. W.; Delhaye, L.; Van Vlierberghe, P.; Eyckerman, S.; Durinck, K.
10.1101/2023.03.08.531704 — cancer biology — Posted on 2023-03-10
3314 KRAB zinc finger proteins ZNF587/ZNF417 protect lymphoma cells from replicative stress-induced inflammation
Martins, F.; Rosspopoff, O.; Carlevaro-Fita, J.; Forey, R.; Offner, S.; Planet, E.; Pulver, C.; Pak, H.; Michaux, J.; Bassani-Sternberg, M.; Turelli, P.; Trono, D.
10.1101/2023.03.08.531722 — cancer biology — Posted on 2023-03-10
3315 Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer
Cook, D. P.; Galpin, K. J.; Rodriguez, G. M.; Shakfa, N.; Wilson-Sanchez, J.; Pereira, M.; Matuszewska, K.; Haagsma, J.; Murshed, H.; Cudmore, A. O.; MacDonald, E.; Tone, A.; Shepherd, T. G.; Petrik, J. J.; Koti, M.; Vanderhyden, B. C.
10.1101/2023.03.09.531888 — cancer biology — Posted on 2023-03-10
3317 Visualizing proteins by expansion microscopy
Shaib, A. H.; Chouaib, A. A.; Chowdhury, R.; Mihaylov, D.; Zhang, C.; Imani, V.; Georgiev, S. V.; Mougios, N.; Monga, M.; Reshetniak, S.; Mimoso, T.; Chen, H.; Fatehbasharzad, P.; Crzan, D.; Alawar, N.; Eilts, J.; Saal, K. A.; Kang, J.; Alvarez, L.; Trenkwalder, C.; Mollenhauer, B.; Outeiro, T. F.; Koester, S.; Preobraschenski, J.; Becherer, U.; Moser, T.; Boyden, E. S.; Aricescu, A. R. A.; Sauer, M.; Opazo, F.; Rizzoli, S.
10.1101/2022.08.03.502284 — biophysics — Posted on 2023-03-10
3319 Cochlear dysfunction as an early biomarker for cognitive decline in normal hearing and mild hearing loss
Medel, V.; Delano, P. H.; Belkhiria, C.; Leiva, A.; De Gatica, C.; Vidal, V.; Navarro, C. F.; San Martin, S.; Martinez, M.; Gierke, C.; Garcia, X.; Cerda, M.; Vergara, R.; Delgado, C.; Farias, G.
10.1101/2023.02.03.527051 — neuroscience — Posted on 2023-03-10
3321 Self-assembly and contraction of micron-scale DNA rings
Illig, M.; Jahnke, K.; Scheffold, M.; Mersdorf, U.; Drechsler, H.; Diez, S.; Göpfrich, K.
10.1101/2023.03.09.531887 — biophysics — Posted on 2023-03-10
3322 Single-cell time series analysis reveals the dynamics of in vivo HSPC responses to inflammation
Bouman, B. J.; Demerdash, Y.; Sood, S.; Gruenschlaeger, F.; Pilz, F.; Itani, A. R.; Kuck, A.; Haas, S.; Haghverdi, L.; Essers, M. A. G.
10.1101/2023.03.09.531881 — cell biology — Posted on 2023-03-10
3324 Identifying Fibrogenic Cells Following Salivary Gland Obstructive Injury
Altrieth, A. L.; O'Keefe, K. J.; Gellatly, V. A.; Tavarez, J. R.; Feminella, S. M.; Moskwa, N. L.; Cordi, C. V.; Turrieta, J. C.; Nelson, D. A.; Larsen, M.
10.1101/2023.03.09.531751 — cell biology — Posted on 2023-03-10
3325 Hepatic Lipid Droplet-Associated Proteome Changes Distinguish Dietary-Induced Fatty Liver from Insulin Resistance in Male Mice.
van Woerkom, A.; Harney, D. J.; Nagarajan, S. R.; Hakeem-Sanni, M. F.; Lin, J.; Hooke, M.; Pulpitel, T.; Cooney, G. J.; Larance, M.; Saunders, D. N.; Brandon, A. E.; Hoy, A. J.
10.1101/2023.03.09.531813 — cell biology — Posted on 2023-03-10
3330 DEK oncoprotein participates in heterochromatin replication via SUMO-dependent nuclear bodies
Pierzynska-Mach, A.; Czada, C.; Vogel, C.; Gwosch, E.; Osswald, X.; Bartoschek, D.; Diaspro, A.; Kappes, F.; Ferrando-May, E.
10.1101/2023.03.09.529154 — cell biology — Posted on 2023-03-10
3331 Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction
Sabogal Guaqueta, A.; Marmolejo-Garza, A.; Trombetta-Lima, M.; Oun, A.; Hunneman, J.; Chen, T.; Koistinaho, J.; Lehtonen, S.; Kortholt, A.; Bakker, B. M.; Eggen, B. J. L.; Boddeke, E.; Dolga, A.
10.1101/2023.03.10.531955 — cell biology — Posted on 2023-03-10
3332 Differential effects of oxytocin receptor antagonist on social rank and other social behavior in male mice
Nasukawa, D.; Yamada, K.; Hirakata, H.; Ujihara, Y.; Tamura, R.; Yatagai, S.; Hayashi, K.; Toda, K.
10.1101/2022.07.23.501222 — neuroscience — Posted on 2023-03-10
3333 BnIR: a multi-omics database with various tools for Brassica napus research and breeding
Yang, Z.; Wang, S.; Wei, L.; Huang, Y.; Liu, D.; Jia, Y.; Luo, C.; Lin, Y.; Liang, C.; Hu, Y.; Dai, C.; Guo, L.; Zhou, Y.; Qing-Yong, Y.
10.1101/2023.01.12.523736 — bioinformatics — Posted on 2023-03-10
3339 Evolutionary constraint and innovation across hundreds of placental mammals
Christmas, M. J.; Kaplow, I. M.; Genereux, D. P.; Dong, M. X.; Hughes, G. M.; Li, X.; Sullivan, P. F.; Hindle, A. G.; Andrews, G.; Armstrong, J. C.; Bianchi, M.; Breit, A. M.; Diekhans, M.; Fanter, C.; Foley, N. M.; Goodman, D. B.; Goodman, L.; Keough, K. C.; Kirilenko, B.; Kowalczyk, A.; Lawless, C.; Lind, A. L.; Meadows, J. R. S.; Moreira, L. R.; Redlich, R. W.; Ryan, L.; Swofford, R.; Valenzuela, A.; Wagner, F.; Wallerman, O.; Brown, A. R.; Damas, J.; Fan, K.; Gatesy, J.; Grimshaw, J.; Johnson, J.; Kozyrev, S. V.; Lawler, A. J.; Marinescu, V. D.; Morrill, K. M.; Osmanski, A.; Paulat, N. S.;
10.1101/2023.03.09.531574 — genomics — Posted on 2023-03-09
3341 Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells
Gowans, F. A.; Thach, D. Q.; Wang, Y.; Poblano, B. E. A.; Dovala, D.; Tallarico, J. A.; McKenna, J. M.; Schirle, M.; Maimone, T. J.; Nomura, D. K.
10.1101/2023.03.09.531918 — biochemistry — Posted on 2023-03-09
3342 Genetic analysis of rab7 mutants in zebrafish
Heutschi, D.; Schmelzer, E.; Aydogan, V.; Schmidt, A.; Belting, H.-G.; Spang, A.; Affolter, M.; Kotini, M. P.
10.1101/2023.03.09.531857 — genetics — Posted on 2023-03-09
3346 Modification of social cheating facilitates the stabilization and chronic infection of polymorphic Pseudomonas aeruginosa population
Zhao, K.; Yang, X.; Zeng, Q.; Zhang, Y.; Li, H.; Li, J. S.; Liu, H.; Du, L.; Wu, Y.; Huang, G.; Huang, T.; Zhang, Y.; Zhou, H.; Wang, X.; Chu, Y.; Zhou, X.
10.1101/2023.03.08.531804 — microbiology — Posted on 2023-03-09
3347 A hybrid and poly-polish workflow for the complete and accurate assembly of phage genomes: a case study of ten przondoviruses
Elek, C. K. A.; Brown, T. L.; Le Viet, T.; Evans, R.; Baker, D. J.; Telatin, A.; Tiwari, S. K.; Al-Khanaq, H.; Thilliez, G.; Kingsley, R. A.; Hall, L. J.; Webber, M. A.; Adriaenssens, E. M.
10.1101/2023.03.09.531871 — microbiology — Posted on 2023-03-09
3351 Sanglifehrin A mitigates multi-organ fibrosis in vivo by inducing secretion of the collagen chaperone cyclophilin B
Flaxman, H. A.; Chrysovergi, M.-A.; Han, H.; Kabir, F.; Lister, R. T.; Chang, C.-F.; Black, K. E.; Lagares, D.; Woo, C. M.
10.1101/2023.03.09.531890 — biochemistry — Posted on 2023-03-09
3352 CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels
Tanzo, J. T.; Li, V. L.; Wiggenhorn, A. L.; Garzon, M. D. M.; Wei, W.; Lyu, X.; Dong, W.; Tahir, U.; Chen, Z.-Z.; Cruz, D. E.; Deng, S.; Shi, X.; Zheng, S.; Guo, Y.; Sims, M.; Abu-Remaileh, M.; Wilson, J. G.; Gerszten, R. E.; Long, J. Z.; Benson, M. D.
10.1101/2023.03.09.531581 — biochemistry — Posted on 2023-03-09
3353 Metabolic Signatures of Performance in Elite World Tour Professional Cyclists
Nemkov, T.; Cendali, F.; Stefanoni, D.; Martinez, J.; Hansen, K. C.; San-Millan, I.; D'Alessandro, A.
10.1101/2022.09.13.507793 — biochemistry — Posted on 2023-03-09
3354 Multiple origins of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
Sinha, A.; Li, Z.; Poole, C. B.; Ettwiller, L.; Lima, N. F.; Ferreira, M. U.; Fombad, F. F.; Wanji, S.; Carlow, C.
10.1101/2021.03.23.436630 — genomics — Posted on 2023-03-09
3361 Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells
Lee, S.-Y.; Cheah, J. S.; Zhao, B.; Xu, C.; Roh, H.; Kim, C. K.; Cho, K. F.; Udeshi, N.; Carr, S. A.; Ting, A. Y.
10.1101/2023.03.09.531939 — molecular biology — Posted on 2023-03-09
3366 A toxic ankyrin cysteine protease effector RipBH of brown rot triggered autophagy-associated cell death
Zheng, X.; Huang, M.; Tan, X.; Wang, B.; Li, Y.; Xue, H.; Cheng, D.; Qiu, H.; Li, W.; Song, B.; Chen, H.
10.1101/2023.03.08.531657 — microbiology — Posted on 2023-03-09
3367 Hadza Prevotella Require Diet-derived Microbiota Accessible Carbohydrates to Persist in Mice.
Gellman, R. H.; Olm, M. R.; Terrapon, N.; Enam, F.; Higginbottom, S. K.; Sonnenburg, J. L.; Sonnenburg, E. D.
10.1101/2023.03.08.531063 — microbiology — Posted on 2023-03-09
3369 Long-B prokaryotic Argonaute systems employ various effectors to confer immunity via abortive infection
Song, X.; Lei, S.; Liu, S.; Liu, Y.; Fu, P.; Zeng, Z.; Yang, K.; Chen, Y.; Li, M.; She, Q.; Han, W.
10.1101/2023.03.09.531850 — microbiology — Posted on 2023-03-09
3373 Delayed formation of neural representations of space in aged mice
McDermott, K. D.; Frechou, M. A.; Jordan, J. T.; Martin, S. S.; Goncalves, J. T.
10.1101/2023.03.03.531021 — neuroscience — Posted on 2023-03-09
3375 FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
Wilde, B. R.; Chakraborty, N.; Matulionis, N.; Hernandez, S.; Ueno, D.; Gee, M. E.; Esplin, E. D.; Ouyang, K.; Nykamp, K.; Shuch, B.; Christofk, H. R.
10.1101/2022.08.15.504023 — cancer biology — Posted on 2023-03-09
3376 Measuring single-cell susceptibility to antibiotics within monoclonal bacterial populations
Le Quellec, L.; Aristov, A.; Guitierrez Ramos, S.; Amselem, G.; Bos, J.; Baharoglu, Z.; Mazel, D.; Baroud, C.
10.1101/2023.03.08.531654 — bioengineering — Posted on 2023-03-09
3377 Structure of the connexin-43 gap junction channel in a putative closed state
Qi, C.; Acosta-Gutierrez, S.; Lavriha, P.; Othman, A.; Lopez-Pigozzi, D.; Bayraktar, E.; Schuster, D.; Picotti, P.; Zamboni, N.; Bortolozzi, M.; Gervasio, F. L.; Korkhov, V. M.
10.1101/2022.03.26.485947 — biochemistry — Posted on 2023-03-09
3379 Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56 delta holoenzyme
Wu, C.-G.; Balakrishnan, V. K.; Parihar, P. S.; Konovolov, K.; Chen, Y.-C.; Merrill, R. A.; Wei, H.; Carragher, B.; Sundaresan, R.; Cui, Q.; Wadzinski, B. E.; Swingle, M. R.; Musiyenko, A.; Honkanen, R.; Suzuki, A.; Strack, S.; Huang, X.; Xing, Y.
10.1101/2023.03.09.530109 — biochemistry — Posted on 2023-03-09
3380 The Nucleotide Transformer: Building and Evaluating Robust Foundation Models for Human Genomics
Dalla-Torre, H.; Gonzalez, L.; Mendoza Revilla, J.; Lopez Carranza, N.; Henryk Grywaczewski, A.; Oteri, F.; Dallago, C.; Trop, E.; Sirelkhatim, H.; Richard, G.; Skwark, M.; Beguir, K.; Lopez, M.; Pierrot, T.
10.1101/2023.01.11.523679 — genomics — Posted on 2023-03-09
3381 Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes
Eme, L.; Tamarit, D.; Caceres, E. F.; Stairs, C.; de Anda, V.; Schon, M.-E.; Seitz, K.; Dombrowski, N.; Lewis, W. H.; Saw, J. H.; Homa, F.; Lombard, J.; Nunoura, T.; Li, W.-J.; Hua, Z.-S.; Chen, L.-X.; Banfield, J.; St. John, E.; Reysenbach, A.-L.; Stott, M. B.; Schramm, A.; Kjeldsen, K. U.; Teske, A. P.; Baker, B. J.; Ettema, T. J. G.
10.1101/2023.03.07.531504 — evolutionary biology — Posted on 2023-03-09
3384 Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
Bilgic, M.; Wu, Q.; Suetsugu, T.; Tsunekawa, Y.; Sitamukai, A.; Kadota, M.; Nishimura, O.; Kuraku, S.; Shimogori, T.; Kiyonari, H.; Matsuzaki, F.
10.1101/2022.05.05.490846 — developmental biology — Posted on 2023-03-09
3386 ZC3H11A interacts with PABPN1 and alters polyadenylation of viral transcripts
Kases, K.; Schubert, E.; Hajikhezri, Z.; Larsson, M.; Andersson, L.; Akusjarvi, G.; Punga, T.; Younis, S.
10.1101/2023.03.09.531914 — molecular biology — Posted on 2023-03-09
3387 The loss of antioxidant activities impairs intestinal epithelium homeostasis by altering lipid metabolism
Ramos-Leon, J.; Valencia, C.; Gutierrez-Mariscal, M.; Rivera-Miranda, D.-A.; Garcia-Melendrez, C.; Covarrubias, L.
10.1101/2023.03.09.531979 — molecular biology — Posted on 2023-03-09
3388 Selection of antibody-binding covalent aptamers
Soxpollard, N.; Strauss, S.; Jungmann, R.; MacPherson, I. S.
10.1101/2023.03.09.530504 — molecular biology — Posted on 2023-03-09
3390 Characterization of skin- and intestine microbial communities in migrating high Arctic lake whitefish and cisco
Hamilton, E. F.; Juurakko, C. L.; Engel, K.; Van Coeverden de Groot, P. J.; Casselman, J. M.; Greer, C. W.; Neufeld, J. D.; Walker, V. K.
10.1101/2023.03.08.531621 — microbiology — Posted on 2023-03-09
3391 Hybrid immunity elicits potent cross-variant ADCC against SARS-CoV-2 through a combination of anti-S1 and S2 antibodies
Grant, M. D.; Bentley, K.; Fielding, C. A.; Hatfield, K. M.; Ings, D. P.; Harnum, D.; Wang, E.; Stanton, R.; Holder, K. A.
10.1101/2023.03.09.531709 — immunology — Posted on 2023-03-09
3392 Intense light unleashes male-male courtship behaviorin wild-type Drosophila
Ueda, A.; Berg, A.; Khan, T.; Ruzicka, M.; Li, S.; Cramer, E.; Iyengar, A.; Wu, C.-F.
10.1101/2022.07.12.499756 — neuroscience — Posted on 2023-03-09
3393 Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of Neurochondrin
Montalban, E.; Giralt, A.; Taing, L.; Nakamura, Y.; Pelosi, A.; Brown, M.; de Pins, B.; Valjent, E.; Martin, M.; Nairn, A. C.; Greengard, P.; Flajolet, M.; Herve, D.; Gambardella, N.; Roussarie, J.-P.; Girault, J.-A.
10.1101/2023.03.07.531496 — neuroscience — Posted on 2023-03-09
3394 Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer's disease
Green, G. S.; Fujita, M.; Yang, H.-S.; Taga, M.; McCabe, C.; Cain, A.; White, C. C.; Schmidtner, A. K.; Wang, Y.; Regev, A.; Menon, V.; Bennett, D. A.; Habib, N.; De Jager, P.
10.1101/2023.03.07.531493 — neuroscience — Posted on 2023-03-09
3396 Dissecting the subcellular forces sculpting early C. elegans embryos
Yamamoto, K.; Ichbiah, S.; Pinto, J.; Delbary, F.; Goehring, N.; Turlier, H.; Charras, G.
10.1101/2023.03.07.531437 — biophysics — Posted on 2023-03-09
3397 Smart Lattice Light Sheet Microscopy for imaging rare and complex cellular events
Shi, Y.; Tabet, J. S.; Milkie, D. E.; Daugird, T. A.; Yang, C. Q.; Giovannucci, A.; Legant, W. R.
10.1101/2023.03.07.531517 — biophysics — Posted on 2023-03-09
3402 High Volume Rate 3-D Ultrasound Imaging Using Fast-Tilting and Redirecting Reflectors
Dong, Z.; Li, S.; Duan, X.; Lowerison, M.; Huang, C.; You, Q.; Chen, S.; Zou, J.; Song, P.
10.1101/2023.03.07.531439 — bioengineering — Posted on 2023-03-09
3404 Deep convolutional and conditional neural networks for large-scale genomic data generation
Yelmen, B.; Decelle, A.; Boulos, L. L.; Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Jay, F.
10.1101/2023.03.07.530442 — genomics — Posted on 2023-03-09
3405 Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions
Luo, R.; Yan, J.; Oh, J. W.; Xi, W.; Shigaki, D.; Wong, W.; Cho, H.; Murphy, D.; Cutler, R.; Rosen, B. P.; Pulecio, J.; Yang, D.; Glenn, R.; Chen, T.; Li, Q. V.; Vierbuchen, T.; Sidoli, S.; Apostolou, E.; Huangfu, D.; Beer, M. A.
10.1101/2023.03.07.531569 — genetics — Posted on 2023-03-09
3408 Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases
Wei, J.; Lambert, T. Y.; Valada, A.; Patel, N.; Walker, K.; Lenders, J.; Schmidt, C. J.; Iskhakova, M.; Alazizi, A.; Mair-Meijers, H.; Mash, D. C.; Luca, F.; Pique-Regi, R.; Bannon, M. J.; Akbarian, S.
10.1101/2023.03.07.531400 — neuroscience — Posted on 2023-03-09
3412 Cellular dynamics under time-varying conditions
Joshi, K.; Roy, S.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.03.07.531540 — biophysics — Posted on 2023-03-09
3413 Public exams decrease anxiety and facilitate deeper conceptual thinking
Wiggins, B.; Lily, L.; Busch, C.; Landys, M.; Shlichta, J. G.; Shi, T.; Ngwenyama, T.
10.1101/2022.04.15.488479 — scientific communication and education — Posted on 2023-03-09
3417 Label-free proteomic comparison reveals ciliary and non- ciliary phenotypes of IFT-A mutants
leggere, j.; Hibbard, J.; Papoulas, O.; Lee, c.; Pearson, C. G.; Marcotte, E. M.; Wallingford, J. B.
10.1101/2023.03.08.531778 — cell biology — Posted on 2023-03-09
3419 Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease
Boeynaems, S.; Ma, X. R.; Yeong, V.; Ginell, G. M.; Chen, J.-H.; Blum, J. A.; Nakayama, L.; Sanyal, A.; Briner, A.; Van Haver, D.; Pauwels, J.; Ekman, A.; Schmidt, H. B.; Sundararajan, K.; Porta, L.; Lasker, K.; Larabell, C.; Hayashi, M. A. F.; Kundaje, A.; Impens, F.; Obermeyer, A.; Holehouse, A. S.; Gitler, A. D.
10.1101/2023.03.09.531820 — cell biology — Posted on 2023-03-09
3422 Adhesion-based capture stabilizes nascent microvilli at epithelial cell junctions
Cencer, C. S.; Silverman, J. B.; Meenderink, L.; Krystofiak, E.; Millis, B. A.; Tyska, M. J.
10.1101/2023.03.08.531705 — cell biology — Posted on 2023-03-09
3423 Standing wave mesoscopy
Foylan, S.; Schniete, J. K.; Koelln, L. S.; Dempster, J.; Hansen, C. G.; Shaw, M.; Bushell, T. J.; McConnell, G.
10.1101/2023.03.08.531677 — cell biology — Posted on 2023-03-09
3424 A MSTNDel273C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia via MEK-ERK-FOSL1 axis
Chen, M.; Zhao, Y.; Xu, X.; Zhang, X.; Zhang, J.; Wu, S.; Liu, Z.; Yuan, Y.; Guo, X.; Qi, S.; Yi, G.; Wang, S.; Li, H.; Wu, A.; Liu, G.; Yu, K.; Deng, S.; Han, H.; Lv, F.; Li, Y.; Lian, Z.
10.1101/2023.03.09.531872 — cell biology — Posted on 2023-03-09
3425 The CGG triplet repeat binding protein 1 counteracts DNA secondary structure-induced transcription-replication conflicts
Ummethum, H.; Lalonde, M.; Werner, M.; Trauner, M.; Chanou, A.; Weiss, M.; Lee, C. S. K.; Kruse, E.; Ettinger, A.; Hamperl, S.
10.1101/2023.03.09.531843 — cell biology — Posted on 2023-03-09
3426 RNA Sensing and Innate Immunity Constitutes a Barrier for Interspecies Chimerism
Hu, Y.; Sun, H.-X.; Sakurai, M.; Jones, A. E.; Liu, L.; Cheng, T.; Zheng, C.; Li, J.; Ravaux, B.; Luo, Z.; Ding, Y.; Liu, T.; Wu, Y.; Chen, E.; Chen, Z.; Abrams, J. M.; Gu, Y.; Wu, J.
10.1101/2023.03.07.531624 — cell biology — Posted on 2023-03-09
3427 CEP76 is a critical regulator of male germ cell transition zone function and tail composition
Houston, B. J.; Merriner, D. J.; Stathatos, G. G.; O'Connor, A. E.; Lopes, A. M.; Conrad, D. F.; Baker, M.; Dunleavy, J. E.; O'Bryan, M. K.
10.1101/2023.03.08.531794 — cell biology — Posted on 2023-03-09
3429 Generation of a SARS-CoV-2 reverse genetics system and novel human lung cell lines that exhibit high virus-induced cytopathology
Khan, J. Q.; Rohamare, M.; Rajamanickam, K.; Bhanumathy, K. K.; Lew, J.; Kumar, A.; Falzarano, D.; Vizeacoumar, F.; Wilson, J. A.
10.1101/2023.03.08.531833 — molecular biology — Posted on 2023-03-09
3432 Inhibition mechanism and antiviral activity of an α-ketoamide based SARS-CoV-2 main protease inhibitor
Chen, X.; Huang, X.; Ma, Q.; Kuzmic, P.; Zhou, B.; Xu, J.; Liu, B.; Jiang, H.; Zhang, W.; Yang, C.; Wu, S.; Huang, J.; Li, H.; Long, C.; Zhao, X.; Xu, H.; Sheng, Y.; Guo, Y.; Niu, C.; Xue, L.; Xu, Y.; Liu, J.; Zhang, T.; Spencer, J.; Deng, W.; Chen, S.-H.; Xiong, X.; Yang, Z.; Zhong, N.
10.1101/2023.03.09.531862 — biochemistry — Posted on 2023-03-09
3433 Transcription Factor Dynamics in Cross-Regulation of Plant Hormone Signaling Pathways
Yin, L.; Zander, M.; Huang, S.-s. C.; Xie, M.; Song, L.; Saldierna Guzman, J. P.; Hann, E.; Shanbhag, B. K.; Ng, S.; Jain, S.; Janssen, B. J.; Clark, N. M.; Walley, J.; Beddoe, T.; Bar-Joseph, Z.; Lewsey, M. G.; Ecker, J. R.
10.1101/2023.03.07.531630 — plant biology — Posted on 2023-03-09
3436 The nucleolar protein GNL3 prevents resection of stalled replication forks.
Lebdy, R.; Canut, M.; Patouillard, J.; Cadoret, J.-C.; Letessier, A.; Ammar, J.; Basbous, J.; Urbach, S.; Miotto, B.; Constantinou, A.; Abou Merhi, R.; Ribeyre, C.
10.1101/2022.10.27.514025 — molecular biology — Posted on 2023-03-09
3437 N-dihydrogalactochitosan reduces mortality in a lethal mouse model of SARS-CoV-2
Weiss, C. M.; Liu, H.; Ball, E. E.; Hoover, A. R.; Wong, T. S.; Wong, C. F.; Lam, S.; Hode, T.; Keel, M. K.; Levenson, R. M.; Chen, W. R.; Coffey, L. L.
10.1101/2021.08.10.455872 — microbiology — Posted on 2023-03-09
3438 Immunological imprinting of humoral immunity to SARS-CoV-2 in children
Dowell, A. C.; Lancaster, T.; Bruton, R.; Ireland, G.; Bentley, C.; Sylla, P.; Zuo, J.; Scott, S.; Jardin, A.; Begum, J.; Roberts, T.; Stephens, C.; Ditta, S.; Shepherdson, R.; Powell, A.; Brent, A.; Brent, B.; Baawuah, F.; Okike, I.; Beckmann, J.; Ahmad, S.; Aiano, F.; Garstang, J.; Ramsay, M.; Azad, R.; Waiblinger, D.; Willet, B.; Wright, J.; Ladhani, S.; Moss, P.
10.1101/2022.07.26.501570 — immunology — Posted on 2023-03-09
3440 Identification of serotonin as a gut regulator of liver hepcidin expression
Coman, T.; Falabregue, M.; Rossignol, J.; Bonneau, P.; Djebar, M.; Bigorgne, A.; Mathieu, J. R.; Foretz, M.; Kautz, L.; Peoc'h, K.; Launay, J.-M.; Maroteaux, L.; Peyssonnaux, C.; Hermine, O.; Cote, F.
10.1101/2021.09.16.460464 — physiology — Posted on 2023-03-09
3441 Sex chromosome - autosome fusions in Heliconius butterflies
Rueda-M, N.; Jiggins, C. D.; Pardo-Diaz, C.; McMillan, W. O.; McCarthy, S.; Kozak, K. M.; Arias, C. F.; Ready, J.; Durbin, R.; Montejo-Kovacevich, G.; Meier, J.; Salazar, C.
10.1101/2023.03.06.531374 — evolutionary biology — Posted on 2023-03-09
3443 Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV 2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case
Tatham, L.; Kipar, A.; Sharp, J.; Kijak, E.; Herriott, J.; Neary, M.; Box, H.; Gallardo Toledo, E.; Valentijn, A.; Cox, H.; Pertinez, H.; Curley, P.; Arshad, U.; Rajoli, R. K.; Rannard, S.; Stewart, J.; Owen, A.
10.1101/2022.01.23.477397 — microbiology — Posted on 2023-03-09
3447 Structural insights into the allosteric inhibition of P2X4 receptors
Shen, C.; Cui, W.; Zhang, Y.; Zhao, Y.; Sheng, D.; Teng, X.; Wang, J.; Hattori, M.
10.1101/2023.03.07.531612 — biophysics — Posted on 2023-03-09
3448 Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
Alghoul, E.; Paloni, M.; Takedachi, A.; Urbach, S.; Barducci, A.; Gaillard, P.-H. L.; Basbous, J.; Constantinou, A.
10.1101/2022.09.20.508711 — biochemistry — Posted on 2023-03-09
3450 Inference of long-range cell-cell force transmission from ECM remodeling fluctuations
Nahum, A.; Koren, Y.; Ergaz, B.; Natan, S.; Miller, G.; Tamir, Y.; Goren, S.; Kolel, A.; Jagadeeshan, S.; Elkabets, M.; Lesman, A.; Zaritsky, A.
10.1101/2020.07.30.223149 — cell biology — Posted on 2023-03-09
3451 An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2
Harvest, C. K.; Abele, T. J.; Yu, C.; Beatty, C. J.; Amason, M. E.; Billman, Z. P.; DePrizio, M. A.; Lacey, C. A.; Maltez, V. I.; Larson, H. N.; McGlaughon, B. D.; Montgomery, S. A.; Miao, E. A.
10.1101/2023.03.07.531568 — immunology — Posted on 2023-03-09
3454 How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell
De Freitas Nascimento, J.; Souza, R. O. O.; Alencar, M. B.; Marsiccobetre, S.; Murillo, A. M.; Damasceno, F. S.; Girard, R. M. B. M.; Marchese, L.; Luevano-Martinez, L. A.; Achjian, R. W.; Haanstra, J. R.; Michels, P.; Silber, A. M.
10.1101/2023.03.07.531645 — biochemistry — Posted on 2023-03-09
3455 The CWI pathway is activated through high hydrostatic pressure, enhancing glycerol efflux via the aquaglyceroporin Fps1 in Saccharomyces cerevisiae
Mochizuki, T.; Tanigawa, T.; Shindo, S.; Suematsu, M.; Oguchi, Y.; Mioka, T.; Kato, Y.; Fujiyama, M.; Hatano, E.; Yamaguchi, M.; Chibana, H.; Abe, F.
10.1101/2022.11.15.516693 — cell biology — Posted on 2023-03-09
3457 Naturally acquired and Vaccine-induced Human Monoclonal Antibodies to Plasmodium vivax Duffy Binding Protein Inhibit Invasion of Plasmodium knowlesi (PvDBPOR) Transgenic Parasites
Watson, Q. D.; Carias, L.; Malachin, A.; Redinger, K. R.; Bosch, J.; Bardelli, M.; Moon, R. W.; Draper, S. J.; Zimmerman, P. A.; King, C. L.
10.1101/2023.03.07.531647 — microbiology — Posted on 2023-03-09
3459 Ventral premotor cortex influences spinal cord activation during force generation
Braass, H.; Feldheim, J.; Chu, Y.; Tinnermann, A.; Finsterbusch, J.; Büchel, C.; Schulz, R.; Gerloff, C.
10.1101/2023.02.22.529375 — neuroscience — Posted on 2023-03-09
3460 Functional and regulatory diversification of circadian rhythm period genes during the evolution of vertebrates
KWAK, J. S.; Leon-Tapia, M. A.; Diblasi, C.; Manousi, D.; Gronvold, L.; Sandvik, G. K.; Saitou, M.
10.1101/2023.03.09.531707 — evolutionary biology — Posted on 2023-03-09
3464 ancIBD - Screening for identity by descent segments in human ancient DNA
Ringbauer, H.; Huang, Y.; Akbari, A.; Mallick, S.; Patterson, N.; Reich, D. E.
10.1101/2023.03.08.531671 — genetics — Posted on 2023-03-09
3465 A genome-wide association study of the Neuroticism general factor
Lee, J. J.; Kim, Y.; Giannelis, A.; Willoughby, E. A.; DeYoung, C. G.
10.1101/2023.03.08.531776 — genetics — Posted on 2023-03-09
3466 Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models
Naia, L.; Shimozawa, M.; Bereczki, E.; Li, X.; Liu, J.; Jiang, R.; Leal, N. S.; Pinho, C. M.; Berger, E.; Falk, V. L.; Dentoni, G.; Ankarcrona, M.; Nilsson, P.
10.1101/2023.03.07.531542 — neuroscience — Posted on 2023-03-09
3467 Isogenic hiPSC models of Turner Syndrome reveal shared roles of inactive X and Y in the human cranial neural crest network
Ahern, D. T.; Bansal, P.; Faustino, I. V.; Glatt-Deeley, H. R.; Kondaveeti, Y.; Banda, E. C.; Pinter, S. F.
10.1101/2023.03.08.531747 — developmental biology — Posted on 2023-03-09
3471 Human outperform mouse Purkinje cells in dendritic complexity and computational capacity
Masoli, S.; Sanchez-Ponce, D.; Vrieler, N.; Abu-Haya, K.; Lerner, V.; Shahar, T.; Nedelescu, H.; Rizza, M. F.; Benavides-Piccione, R.; DeFelipe, J.; Yarom, Y.; Munoz, A.; D'Angelo, E.
10.1101/2023.03.08.531672 — neuroscience — Posted on 2023-03-09
3475 A stable, distributed code for cue value in mouse cortex during reward learning
Ottenheimer, D. J.; Hjort, M. M.; Bowen, A. J.; Steinmetz, N. A.; Stuber, G. D.
10.1101/2022.07.13.499930 — neuroscience — Posted on 2023-03-08
3478 Genomic characteristics and clinical significance of CD56+ Circulating Tumor Cells in Small Cell Lung Carcinoma
Ricordel, C.; Chaillot, L.; Vlachavas, E.-I.; Logotheti, M.; Jouannic, A.; Desvallees, T.; Lecuyer, G.; Aubry, M.; Kontogianni, G.; Mastrokalou, C.; Jouan, F.; Jarry, U.; Corre, R.; Le Guen, Y.; Guillaudeux, T.; Lena, H.; Chatziioannou, A.; Pedeux, R.
10.1101/2022.04.30.487775 — cancer biology — Posted on 2023-03-08
3482 Convolutional-recurrent neural networks approximate diffusion tractography from T1-weighted MRI and associated anatomical context
Cai, L. Y.; Lee, H. H.; Newlin, N. R.; Kerley, C. I.; Kanakaraj, P.; Yang, Q.; Johnson, G. W.; Moyer, D.; Schilling, K. G.; Rheault, F.; Landman, B. A.
10.1101/2023.02.25.530046 — bioengineering — Posted on 2023-03-08
3485 Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout aging
Serrano, I.; Hirose, M. H.; Valentine, C.; Austin, S.; Schmidt, E.; Pratt, G.; Williams, L.; Salk, J.; Ibrahim, S.; Sudmant, P. H.
10.1101/2023.03.06.531392 — genomics — Posted on 2023-03-08
3487 Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture
Wei, Y.; Zhang, E.; Yu, L.; Ci, B.; Guo, L.; Sakurai, M.; Takii, S.; Liu, J.; Schmitz, D.; Ding, Y.; Zhan, L.; Zheng, C.; Sun, H.-X.; Xu, L.; Okamura, D.; Ji, W.; Tan, T.; Wu, J.
10.1101/2023.03.07.531525 — developmental biology — Posted on 2023-03-08
3488 Regulatory principles of human mitochondrial gene expression revealed by kinetic analysis of the RNA life cycle
McShane, E.; Couvillion, M.; Ietswaart, R.; Prakash, G.; Smalec, B. M.; Soto, I.; Baxter-Koenigs, A. R.; Choquet, K.; Churchman, L. S.
10.1101/2023.02.09.527880 — cell biology — Posted on 2023-03-08
3491 Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis in mice
Wynn, E. A.; Dide-Agossou, C.; Reichlen, M.; Rossmassler, K.; Al Mubarak, R.; Reid, J. J.; Tabor, S. T.; Born, S. E.; Ransom, M. R.; Davidson, R. M.; Walton, K. N.; Benoit, J. B.; Hoppers, A.; Bauman, A. A.; Massoudi, L. M.; Dolganov, G.; Nahid, P.; Voskuil, M. I.; Robertson, G. T.; Moore, C. M.; Walter, N. D.
10.1101/2023.03.06.531356 — microbiology — Posted on 2023-03-08
3493 Modulation of locus coeruleus neurons and strong release of noradrenaline during acute hippocampal seizures in rats
Larsen, L. E.; Caestecker, S.; Stevens, L.; van Mierlo, P.; Carrette, E.; Boon, P.; Vonck, K.; Raedt, R.
10.1101/2023.03.06.531292 — neuroscience — Posted on 2023-03-08
3494 Different ways of evolving tool-using brains in teleosts and amniotes
Estienne, P.; Simion, M.; Hagio, H.; Yamamoto, N.; Jenett, A.; Yamamoto, K.
10.1101/2022.11.04.515163 — neuroscience — Posted on 2023-03-08
3495 Spontaneous Necker-Cube Reversals are not that Spontaneous
Wilson, M.; Hecker, L.; Joos, E.; Aertsen, A.; Tebartz van Elst, L.; Kornmeier, J.
10.1101/2023.03.06.531257 — neuroscience — Posted on 2023-03-08
3496 TEAD1 is crucial for myelination, Remak bundles and functional regeneration of peripheral nerves
Grove, M.; Kim, H.; Pang, S.; Amaya, J. P.; Hu, G.; Zhou, J.; Lemay, M.; Son, Y.-J.
10.1101/2023.02.27.530298 — neuroscience — Posted on 2023-03-08
3501 A murine model of hnRNPH2-related neurodevelopmental disorder recapitulates clinical features of human disease and reveals a mechanism for genetic compensation of HNRNPH2
Korff, A.; Yang, X.; O'Donovan, K.; Gonzalez, A.; Teubner, B. J. W.; Nakamura, H.; Messing, J.; Yang, F.; Carisey, A.; Wang, Y.-D.; Patni, T.; Tillman, H.; Zakharenko, S. S.; Chook, Y. M.; Taylor, J. P.; Kim, H. J.
10.1101/2022.03.17.484791 — neuroscience — Posted on 2023-03-08
3503 Disentangling the effects of metabolic cost and accuracy on movement vigor
Bruening, G. W.; Sukumar, S.; Courter, R. J.; O'Brien, M. K.; Ahmed, A. A.
10.1101/2023.02.08.527734 — neuroscience — Posted on 2023-03-08
3505 Phased grapevine genome sequence of an Rpv12 carrier for biotechnological exploration of resistance to Plasmopara viticola
Frommer, B.; Muellner, S.; Holtgraewe, D.; Viehoever, P.; Huettel, B.; Toepfer, R.; Weisshaar, B.; Zyprian, E. M.
10.1101/2022.08.06.503030 — plant biology — Posted on 2023-03-08
3509 α-Synuclein Aggregation is Triggered by Amyloid-β Oligomers via Heterogenous Primary Nucleation
Vadukul, D. M.; Papp, M.; Thrush, R. J.; Wang, J.; Jin, Y.; Arosio, P.; Aprile, F. A.
10.1101/2022.06.20.496547 — biochemistry — Posted on 2023-03-08
3510 Development and Application of Home Cage Monitoring in Laboratory Mice and Rats: a Systematic Review
Kahnau, P.; Mieske, P.; Wilzopolski, J.; Kalliokoski, O.; Mandillo, S.; Hölter, S. M.; Voikar, V.; Amfim, A.; Badurek, S.; Bartelik, A.; Caruso, A.; Cater, M.; Ey, E.; Golini, E.; Jaap, A.; Hrncic, D.; Kiryk, A.; Lang, B.; Loncarevic-Vasiljkovic, N.; Meziane, H.; Radzeviciene, A.; Rivalan, M.; Scattoni, M. L.; Torquet, N.; Trifkovic, J.; Ulfhake, B.; Thöne-Reineke, C.; Diederich, K.; Lewejohann, L.; Hohlbaum, K.
10.1101/2023.03.07.531465 — animal behavior and cognition — Posted on 2023-03-08
3511 Single-cell Genome-and-Transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones
Theunis, K.; Vanuytven, S.; Rambow, F.; Brown, D.; Vanderhaegen, M.; Marin-Bejar, O.; Rogiers, A.; Vanraemdonck, N.; Leucci, E.; Demeulemeester, J.; Sifrim, A.; Marine, J.-C.; Voet, T.
10.1101/2023.01.13.521174 — genomics — Posted on 2023-03-08
3519 Evolutionary history of the transposon-invaded Pithoviridae genomes
Rigou, S.; Schmitt, A.; Alempic, J.-M.; Lartigue, A.; Vendloczki, P.; Abergel, C.; Claverie, J.-M.; Legendre, M.
10.1101/2023.03.08.530996 — genomics — Posted on 2023-03-08
3521 Loss of Gasdermin D is protective against influenza virus-induced inflammation and mortality
Speaks, S.; Zani, A.; Solstad, A.; Kenney, A.; Zhang, L.; Eddy, A. C.; Amer, A. O.; Robinson, R.; Cai, C.; Ma, J.; Hemann, E.; Forero, A.; Yount, J.
10.1101/2023.03.08.531787 — immunology — Posted on 2023-03-08
3525 Alterations of the TGFb-sequestration complex member ADAMTSL1 levels are associated with muscular defects and rhabdomyosarcoma aggressiveness
Juban, G.; Bertrand-Chapel, A.; Meyer, S.; Kneppers, A. E. M.; Huchede, P.; Gallerne, C.; Benayoun, R.; Cohen, E.; Lopez-Gonzalez, A.; Larbi, S. B.; Creveaux, M.; Vaille, L.; Bouvier, A.; Theodore, M.; Broutier, L.; Dutour, A.; Cordier-Bussat, M.; Blay, J.-Y.; Streichenberger, N.; Picard, C.; Corradini, N.; Allamand, V.; Castets, P.; Mounier, R.; CASTETS, M.
10.1101/2023.03.07.531559 — cancer biology — Posted on 2023-03-08
3526 H3K9 methylation enhances HP1-associated epigenetic silencing complex assembly and suppresses off-chromatin binding
Chen, Z.; Seman, M.; Farhat, A.; Fyodorova, Y.; Biswas, S.; Levashkevich, A.; Freddolino, P.; Biteen, J. S.; Ragunathan, K.
10.1101/2023.03.08.531771 — biophysics — Posted on 2023-03-08
3528 Genome mining unveils a class of ribosomal peptides with two amino termini
Ren, H.; Dommaraju, S. R.; Huang, C.; Cui, H.; Pan, Y.; Nesic, M.; Zhu, L.; Sarlah, D.; Mitchell, D. A.; Zhao, H.
10.1101/2023.03.08.531785 — biochemistry — Posted on 2023-03-08
3530 Embracing firefly flash pattern variability with data-driven species classification
Martin, O. L.; Sarfati, R.; Nguyen, C.; Chowdhury, M.; Iuzzolino, M. L.; Nguyen, D. M. T.; Layer, R. M.; Peleg, O.
10.1101/2023.03.08.531653 — ecology — Posted on 2023-03-08
3533 Differentiated Oral Epithelial Cells Support the HPV Life Cycle
Seaman, W. T.; Saladyanant, T.; Madden, V.; Webster-Cyriaque, J.
10.1101/2023.03.08.531611 — microbiology — Posted on 2023-03-08
3534 Functional analysis of flavivirus replicase by deep mutational scanning of dengue NS5
Suphatrakul, A.; Posiri, P.; Srisuk, N.; Nantachokchawapan, R.; Onnome, S.; Mongkolsapaya, J.; Siridechadilok, B.
10.1101/2023.03.07.531617 — microbiology — Posted on 2023-03-08
3535 Inhibitory effect of Ephedra herba on human norovirus infection in human intestinal organoids
Hayashi, T.; Murakami, K.; Ando, H.; Ueno, S.; Kobayashi, S.; Muramatsu, M.; Tanikawa, T.; Kitamura, M.
10.1101/2023.03.08.531477 — microbiology — Posted on 2023-03-08
3541 Promyelocytic Leukemia Protein regulates Angiogenesis and Epithelial-Mesenchymal Transition to limit metastasis in MDA-MB-231 breast cancer cells.
Vogiatzoglou, A. P.; Spanou, S.; Sachini, N.; Drakos, E.; Nikolaou, C.; Makatounakis, T.; Kretsovali, A.; Papamatheakis, J.
10.1101/2022.08.28.505601 — cancer biology — Posted on 2023-03-08
3542 Novel native extracellular matrix probes to target patient- and tissue- specific cell-microenvironment interactions by force spectroscopy
Holuigue, H.; Nacci, L.; Di Chiaro, P.; Chighizola, M.; Locatelli, I.; Schulte, C.; Alfano, M.; Diaferia, G. R.; Podesta', A.
10.1101/2022.12.02.518867 — biophysics — Posted on 2023-03-08
3543 Rapid and Efficient Ambient Temperature X-ray Crystal Structure Determination at Turkish Light Source
Gul, M.; Ayan, E.; Destan, E.; Johnson, J. A.; Shafiei, A.; Kepceoglu, A.; Yilmaz, M.; Ertem, F. B.; Yapici, I.; Tosun, B.; Baldir, N.; Tokay, N.; Nergiz, Z.; Karakadioglu, G.; Paydos, S. S.; Kulakman, C.; Ferah, C. K.; Guven, O.; Atalay, N.; Akcan, E. K.; Cetinok, H.; Arslan, N. E.; Sabanoglu, K.; Asci, B.; Tavli, S.; Altuntas, S.; Otsuka, M.; Fujita, M.; Tekin, S.; Ciftci, H.; Durdagi, S.; Karaca, E.; Kaplan Turkoz, B.; Kabasakal, B. V.; Kati, A.; DeMirci, H.
10.1101/2022.10.12.511637 — biophysics — Posted on 2023-03-08
3548 Gene Expression Profiling Unveils the Temporal Dynamics of CIGB-300-Regulated Transcriptome in AML Cells
Vazquez-Blomquist, D.; Ramon, A. C.; Rosales, M.; Perez, G. V.; Rosales, A.; Palenzuela, D.; Perera, Y.; Perea, S. E.
10.1101/2023.03.06.530131 — cancer biology — Posted on 2023-03-08
3552 Demographic Modeling of Admixed Latin American Populations from Whole Genomes
Medina-Munoz, S. G.; Ortega-Del Vecchyo, D.; Cruz-Hervert, L. P.; Ferreyra-Reyes, L.; Garcia-Garcia, L.; Moreno-Estrada, A.; Ragsdale, A.
10.1101/2023.03.06.531060 — evolutionary biology — Posted on 2023-03-08
3553 Logging disrupts the ecology of molecules in headwater streams
Freeman, E. C.; Emilson, E. J.; Webster, K.; Dittmar, T.; Tanentzap, A. J.
10.1101/2023.03.07.531469 — ecology — Posted on 2023-03-08
3554 Vaccination with mycobacterial lipid loaded nanoparticle leads to lipid antigen persistence and memory differentiation of antigen-specific T cells
Morgun, E.; Zhu, J.; Almunif, S.; Bobbala, S.; Aguilar, M. S.; Wang, J.; Conner, K.; Cui, Y.; Cao, L.; Seshadri, C.; Scott, E. A.; Wang, C.-R.
10.1101/2023.03.07.531489 — immunology — Posted on 2023-03-08
3559 Time series of chicken stool metagenomics and egg metabolomics in changing production systems
Rosch, M. E. G.; Rehner, J.; Schmartz, G. P.; Keller, V.; Becker, S. L.; Manier, S. K.; Mueller, R.; Keller, A.; Meyer, M. R.; Becker, U. M.
10.1101/2023.03.06.531264 — zoology — Posted on 2023-03-08
3563 Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection through aging
Serrano, I.; Hirose, M. H.; Valentine, C.; Austin, S.; Schmidt, E.; Pratt, G.; Williams, L.; Salk, J.; Ibrahim, S.; Sudmant, P. H.
10.1101/2023.03.06.531392 — genomics — Posted on 2023-03-08
3564 Variant-specific Mendelian Risk Prediction Model
Bae, E.; Dias, J.-A.; Huang, T.; Chen, J.; Parmigiani, G.; Rebbeck, T. R.; Braun, D.
10.1101/2023.03.06.531363 — genetics — Posted on 2023-03-08
3565 SIN3 acts in distinct complexes to regulate the germline transcriptional program in C. elegans
Caron, M.; Robert, V. J.; Gely, L.; Adrait, A.; Pakulska, V.; Coute, Y.; Chevalier, M.; Riedel, C. G.; Bedet, C.; Palladino, F.
10.1101/2023.03.07.531480 — genetics — Posted on 2023-03-08
3566 Sex chromosome - autosome fusions in Heliconius butterflies
Rueda-M, N.; Jiggins, C. D.; Pardo-Diaz, C.; McMillan, W. O.; McCarthy, S.; Kozak, K. M.; Arias, C. F.; Ready, J.; Durbin, R.; Montejo-Kovacevich, G.; Meier, J.; Salazar, C.
10.1101/2023.03.06.531374 — evolutionary biology — Posted on 2023-03-08
3569 Urban living can rescue Darwin's finches from the lethal effects of invasive vampire flies
Knutie, S. A.; Webster, C. N.; Vaziri, G. J.; Albert, L.; Harvey, J. A.; LaRue, M.; Verrett, T. B.; Soldo, A.; Koop, J. A. H.; Chaves, J. A.; Wegrzyn, J. L.
10.1101/2023.03.06.531275 — ecology — Posted on 2023-03-08
3571 Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
Hasegawa, T.; Oka, T.; Son, H. G.; Oliver-Garcia, V. S.; Azin, M.; Eisenhaure, T. M.; Lieb, D. J.; Hacohen, N.; Demehri, S.
10.1101/2023.03.06.531282 — immunology — Posted on 2023-03-08
3574 Integration of Avidity and Differentiation is enabled by CD8+ T-cell sensing of IFN-γ
Uhl, L. F. K.; Cai, H.; Mahale, J. N.; MacLean, A. J.; Mazet, J. M.; He, A. J.; Lau, D.; Elliott, T.; Gerard, A.
10.1101/2023.03.06.531375 — immunology — Posted on 2023-03-08
3578 Computational modeling of reinforcement learning and functional neuroimaging of probabilistic reversal dissociates compulsive behaviors in Gambling and Cocaine Use Disorders
Zuhlsdorff, K.; Verdejo-Roman, J.; Clark, L.; Albein-Urios, N.; Soriano-Mas, C.; Cardinal, R.; Robbins, T.; Dalley, J. W.; Verdejo-Garcia, A.; Kanen, J. W.
10.1101/2023.03.06.531272 — neuroscience — Posted on 2023-03-08
3581 Challenging popular belief, mosquito larvae breathe underwater
Alvarez-Costa, A.; Leonardi, M. S.; Giraud, S.; Schilman, P. E.; Lazzari, C. R.
10.1101/2023.03.06.531304 — zoology — Posted on 2023-03-08
3582 MK2 deficiency decreases mortality during the inflammatory phase after myocardial infarction in mice
Trepanier, J.; Nawaito, S. A.; Sahadevan, P.; Sahmi, F.; Duquette, N.; Gelinas, D.; Gillis, M.-A.; Shi, Y.; Torok, C.; Clavet-Lanthier, M.-E.; Gaestel, M.; Sirois, M. G.; Tardif, J.-C.; Allen, B. G.
10.1101/2023.03.06.531384 — physiology — Posted on 2023-03-08
3585 Reactive blue dye detects male reproductive toxicity
Yokota, S.; Wakayama, T.; Miyaso, H.; Suga, K.; Fujinoki, M.; Kaneko, S.; Kitajima, S.
10.1101/2023.03.06.531276 — pharmacology and toxicology — Posted on 2023-03-08
3588 Climate Change Factors Interact to Shift Functional Microbial Composition in Peatlands
Kilner, C. L.; Carrell, A. A.; Wieczynski, D. J.; Votzke, S.; Yammine, A.; DeWitt, K.; Pelletier, D. A.; Weston, D. J.; Gibert, J. P.
10.1101/2023.03.06.531192 — ecology — Posted on 2023-03-08
3589 Symbiotic acacia ants drive nesting behavior by birds in an African savanna
Lujan, E.; Nielsen, R.; Short, Z.; Wicks, S.; Watetu, W. N.; Khasoha, L. M.; Palmer, T. M.; Goheen, J. R.; Alston, J. M.
10.1101/2023.03.06.531340 — ecology — Posted on 2023-03-08
3590 The novel coronary artery disease risk factor ADAMTS-7 modulates atherosclerotic plaque formation by degradation of TIMP-1
Sharifi, A.; Wierer, M.; Dang, T. A.; Milic, J.; Moggio, A.; Sachs, N.; von Scheidt, M.; Hinterdobler, J.; Müller, P.; Werner, J.; Stiller, B.; Aherrahrou, Z.; Erdmann, J.; Zaliani, A.; Graettinger, M.; Reinshagen, J.; Gul, S.; Gribbon, P.; Maegdefessel, L.; Bernhagen, J.; Sager, H. B.; Mann, M.; Schunkert, H.; Kessler, T.
10.1101/2023.03.06.531428 — molecular biology — Posted on 2023-03-08
3591 Metabolic reprogramming and flux to cell envelope precursors in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibiotics
Zeden, M. S.; Gallagher, L. A.; Bueno, E.; Nolan, A.; Ahm, J.; Shinde, D.; Razvi, F.; Sladek, M.; Burke, O.; O'Neill, E.; Fey, P. D.; Cava, F.; Thomas, V. C.; O'Gara, J. P.
10.1101/2023.03.03.530734 — microbiology — Posted on 2023-03-08
3592 Novel determinant of antibiotic resistance: a clinically selected Staphylococcus aureus clpP mutant survives daptomycin treatment by reducing binding of the antibiotic and adapting a rod-shaped morphology
Xu, L.; Henriksen, C.; Mebus, V. H.; Guerillot, R.; Petersen, A.; Jacques, N.; Jiang, J.-H.; Derks, R.; Sanchez-Lopez, E.; Giera, M.; Leeten, K.; Stinear, T. P.; Oury, C.; Howden, B. P.; Peleg, A. Y.; Frees, D.
10.1101/2023.03.06.531458 — microbiology — Posted on 2023-03-08
3593 The cell type composition of the adult mouse brain revealed by single cell and spatial genomics
Langlieb, J.; Sachdev, N.; Balderrama, K.; Nadaf, N.; Raj, M.; Murray, E.; Webber, J.; Vanderburg, C.; Gazestani, V.; Tward, D.; Mezias, C.; Li, X.; Norton, T.; Mitra, P. P.; Chen, F.; Macosko, E.
10.1101/2023.03.06.531307 — neuroscience — Posted on 2023-03-08
3594 Continued dysfunction of capillary pericytes promotes no-reflow after experimental stroke in vivo
Shrouder, J. J.; Filser, S.; Varga, D. P.; Mamrak, U.; Besson-Girard, S.; Bulut-Impraim, B.; Seker, F. B.; Gesierich, B.; Laredo, F.; Wehn, A. C.; Khalin, I.; Bayer, P.; Liesz, A.; Gokce, O.; Plesnila, N.
10.1101/2023.03.06.531258 — neuroscience — Posted on 2023-03-08
3601 Novel axonemal protein ZMYND12 is required for flagellum function and male fertility
Dacheux, D.; Martinez, G.; Broster Reix, C. E.; Beurois, J.; Tounkara, M.; Dupuy, J.-W.; Robinson, D. R.; Loeuillet, C.; Lambert, E.; Wehbe, Z.; Amiri-Yekta, A.; Daneshipour, A.; Hosseini, S.-H.; Zouari, R.; Fourati Ben Mustapha, S.; Halouani, L.; Jiang, X.; Shen, Y.; Liu, C.; Thierry-Mieg, N.; Septier, A.; Bidart, M.; Satre, V.; Cazin, C.; Kherraf, Z.-E.; Arnoult, C.; Ray, P. F.; Toure, A.; Bonhivers, M.; Coutton, C.
10.1101/2023.03.07.531490 — genetics — Posted on 2023-03-08
3606 MAPT expression is regulated by long-range interactions with cis-regulatory elements
Rogers, B. B.; Anderson, A. G.; Lauzon, S. N.; Davis, M. N.; Hauser, R. M.; Roberts, S. C.; Rodriguez-Nunez, I.; Trausch-Lowther, K.; Barinaga, E. A.; Mackiewicz, M.; Roberts, B. S.; Cooper, S. J.; Rizzardi, L. F.; Myers, R. M.; Cochran, J. N.
10.1101/2023.03.07.531520 — genomics — Posted on 2023-03-08
3608 Stealth hunters: landing force predicts hunting success in Barn Owls
Schalcher, K.; Milliet, E.; Sechaud, R.; Buehler, R.; Almasi, B.; Pottier, S.; Becciu, P.; Roulin, A.; Shepard, E. L. C.
10.1101/2023.03.07.531523 — animal behavior and cognition — Posted on 2023-03-08
3609 Development and Application of Home Cage Monitoring in Laboratory Mice and Rats: a Systematic Review
Kahnau, P.; Mieske, P.; Wilzopolski, J.; Kalliokoski, O.; Mandillo, S.; Hölter, S. M.; Voikar, V.; Amfim, A.; Badurek, S.; Bartelik, A.; Caruso, A.; Cater, M.; Ey, E.; Golini, E.; Jaap, A.; Hrncic, D.; Kiryk, A.; Lang, B.; Loncarevic-Vasiljkovic, N.; Meziane, H.; Radzeviciene, A.; Rivalan, M.; Scattoni, M. L.; Torquet, N.; Trifkovic, J.; Ulfhake, B.; Thöne-Reineke, C.; Diederich, K.; Lewejohann, L.; Hohlbaum, K.
10.1101/2023.03.07.531465 — animal behavior and cognition — Posted on 2023-03-08
3612 Structurally divergent and recurrently mutated regions of primate genomes
Mao, Y.; Harvey, W. T.; Porubsky, D.; Munson, K. M.; Hoekzema, K.; Lewis, A. P.; Audano, P. A.; Rozanski, A.; Yang, X.; Zhang, S.; Gordon, D. S.; Wei, X.; Logsdon, G. A.; Haukness, M.; Dishuck, P. C.; Jeong, H.; del Rosario, R.; Bauer, V. L.; Fattor, W. T.; Wilkerson, G. K.; Lu, Q.; Paten, B.; Feng, G.; Sawyer, S. L.; Warren, W. C.; Carbone, L.; Eichler, E. E.
10.1101/2023.03.07.531415 — genomics — Posted on 2023-03-07
3613 From maternal glucocorticoid and thyroid hormones to epigenetic regulation of gene expression: an experimental study in a wild bird species
Hukkanen, M.; Hsu, B.-Y.; Cossin-Sevrin, N.; Crombecque, M.; Delaunay, A.; Hollmen, L.; Kaukonen, R.; Konki, M.; Lund, R.; Marciau, C.; Stier, A.; Ruuskanen, S.
10.1101/2023.03.07.531470 — evolutionary biology — Posted on 2023-03-07
3614 A sample preparation procedure enables acquisition of 2-channel super-resolution 3D STED image of an entire oocyte
Frolikova, M.; Blazikova, M.; Capek, M.; Chmelova, H.; Valecka, J.; Kolackova, V.; Valaskova, E.; Gregor, M.; Komrskova, K.; Horvath, O.; Novotny, I.
10.1101/2023.03.07.531472 — cell biology — Posted on 2023-03-07
3617 Mapping the Complex Genetic Landscape of Human Neurons
Sun, C.; Kathuria, K.; Emery, S. B.; Kim, B.; Burbulis, I. E.; Shin, J.; Brain Somatic Mosaicism Network, ; Weinberger, D. R.; Moran, J. V.; Kidd, J. M.; Mills, R. E.; McConnell, M. J.
10.1101/2023.03.07.531594 — neuroscience — Posted on 2023-03-07
3620 O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology
Balana, A. T.; Mahul-Mellier, A.-L.; Nguyen, B. A.; Horvath, M.; Javed, A.; Hard, E. R.; Jasiqi, Y.; Singh, P.; Afrin, S.; Pedretti, R.; Singh, V.; Lee, V. M.-Y.; Luk, K. C.; Saelices, L.; Lashuel, H. A.; Pratt, M. R.
10.1101/2023.03.07.531573 — biochemistry — Posted on 2023-03-07
3621 Cortico-Striatal Beta-Oscillations as a Marker of Learned Reward Value
Koloski, M. F.; Hulyalkar, S.; Tang, T.; Wu, X.; Fakhraei, L.; Barnes, S. A.; Mishra, J.; Ramanathan, D. S.
10.1101/2022.10.24.513264 — animal behavior and cognition — Posted on 2023-03-07
3625 Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Phan, Q. M.; Salz, L.; Kindl, S. S.; Lopez, J. S.; Thompson, S. M.; Makkar, J.; Driskell, I. M.; Driskell, R. R.
10.1101/2023.03.07.531478 — developmental biology — Posted on 2023-03-07
3626 Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture
Wu, J.; Wei, Y.; Zhang, E.; Yu, L.; Guo, L.; Sakurai, M.; Takii, S.; Schmitz, D.; Ding, Y.; Zheng, C.; Sun, H.; Xu, L.; Okamura, D.; Ji, W.; Tan, T.; Zhan, L.; Ci, B.; Liu, J.
10.1101/2023.03.07.531525 — developmental biology — Posted on 2023-03-07
3627 Zebrahub - Multimodal Zebrafish Developmental Atlas Reveals the State Transition Dynamics of Late Vertebrate Pluripotent Axial Progenitors
Lange, M.; Granados, A.; VijayKumar, S.; Bragantini, J.; Ancheta, S.; Santhosh, S.; Borja, M.; Kobayashi, H.; McGeever, E.; Solak, A. C.; Yang, B.; Zhao, X.; Liu, Y.; Detweiler, A.; Paul, S.; Mekonen, H.; Lao, T.; Banks, R.; Jacobo, A.; Balla, K.; Awayan, K.; D'souza, S.; Haase, R.; Dizeux, A.; Pourquie, O.; Gomez-Sjoberg, R.; Huber, G.; Serra, M.; Neff, N.; Pisco, A.; Royer, L. A.
10.1101/2023.03.06.531398 — developmental biology — Posted on 2023-03-07
3628 The pleiotropic functions of Pri smORF peptides synchronise leg development regulators
Markus, D.; Pelletier, A.; Boube, M.; Port, F.; Boutros, M.; Payre, F.; Obermayer, B.; Zanet, J.
10.1101/2023.03.07.531572 — developmental biology — Posted on 2023-03-07
3629 An important role for triglyceride in regulating spermatogenesis
Chao, C. F.; Pesch, Y.-Y.; Yu, H.; Wang, C.; Aristizabal, M. J.; Huan, T.; Tanentzapf, G.; Rideout, E.
10.1101/2022.12.16.520841 — developmental biology — Posted on 2023-03-07
3630 Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease.
Zaver, S. A. A.; Sarkar, M. K.; Egolf, S.; Zou, J.; Tiwaa, A.; Capell, B. C.; Gudjonsson, J. E.; Simpson, C. L.
10.1101/2023.03.07.531620 — cell biology — Posted on 2023-03-07
3631 Temporal Coordination of the Transcription Factor Response to H2O2 stress
Jose, E.; March-Steinman, W.; Wilson, B. A.; Shanks, L.; Paek, A. L.
10.1101/2023.03.07.531593 — cell biology — Posted on 2023-03-07
3633 Replisome loading reduces chromatin motion independent of DNA synthesis
Pabba, M. K.; Ritter, C.; Chagin, V. O.; Stear, J. H.; Loerke, D.; Kolobynina, K.; Prorok, P.; Schmid, A. K.; Leonhardt, H.; Rohr, K.; Cardoso, M. C.
10.1101/2023.03.07.531331 — cell biology — Posted on 2023-03-07
3634 CRISPR/Cas9-based edition of frataxin gene in Dictyostelium discoideum for Friedreich's Ataxia disease modeling
Gentili, H. G.; Pignataro, M. F.; Olmos, J.; Pavan, M. F.; Ibanez, L. I.; Santos, J.; Velazquez, F.
10.1101/2023.02.27.530330 — cell biology — Posted on 2023-03-07
3635 Single-cell multi-omic analysis of thymocyte development reveals drivers of CD4/CD8 lineage commitment
Steier, Z.; Aylard, D. A.; McIntyre, L. L.; Baldwin, I.; Kim, E. J. Y.; Lutes, L. K.; Ergen, C.; Huang, T.-S.; Robey, E. A.; Yosef, N.; Streets, A.
10.1101/2021.07.12.452119 — immunology — Posted on 2023-03-07
3636 Serotonergic Modulation of Spinal Circuitry Restores Motor Function after Chronic Spinal Cord Injury
Walvekar, S.; Robinson, R. B.; Chadwick, H. M.; Burch, R. M.; Ding, H.; Perlmutter, S. I.; Moorjani, S.
10.1101/2022.10.04.510858 — neuroscience — Posted on 2023-03-07
3637 A molecularly defined and spatially resolved cell atlas of the whole mouse brain
Zhang, M.; Pan, X.; Jung, W.; Halpern, A.; Eichhorn, S. W.; Lei, Z.; Cohen, L.; Smith, K. A.; Tasic, B.; Yao, Z.; Zeng, H.; Zhuang, X.
10.1101/2023.03.06.531348 — neuroscience — Posted on 2023-03-07
3639 Spontaneous Necker-Cube Reversals are not that Spontaneous
Wilson, M.; Hecker, L.; Joos, E.; Aertsen, A.; Tebartz van Elst, L.; Kornmeier, J.
10.1101/2023.03.06.531257 — neuroscience — Posted on 2023-03-07
3640 Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus
Lemcke, R.; Egebjerg, C.; Berendtsen, N. T.; Egerod, K. L.; Thomsen, A. R.; Pers, T. H.; Christensen, J. P.; Kornum, B. R.
10.1101/2023.03.06.530999 — neuroscience — Posted on 2023-03-07
3641 Modulation of locus coeruleus neurons and strong release of noradrenaline during acute hippocampal seizures in rats
Larsen, L. E.; Caestecker, S.; Stevens, L.; van Mierlo, P.; Carrette, E.; Boon, P.; Vonck, K.; Raedt, R.
10.1101/2023.03.06.531292 — neuroscience — Posted on 2023-03-07
3642 The effect of pulse shape in theta-burst stimulation: monophasic vs biphasic TBS
Wendt, K.; Memarian Sorkhabi, M.; Stagg, C. J.; Fleming, M. K.; Denison, T.; O'Shea, J.
10.1101/2023.03.06.531158 — neuroscience — Posted on 2023-03-07
3644 In vivo photopharmacology with a caged mu opioid receptor agonist drives rapid changes in behavior
Ma, X.; Johnson, D. A.; He, X. J.; Layden, A. E.; McClain, S. P.; Yung, J.; Banghart, M. R.
10.1101/2021.09.13.460181 — neuroscience — Posted on 2023-03-07
3648 Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis
Baer, L.; Barthelson, K.; Postlethwait, J.; Adelson, D. L.; Pederson, S. M.; Lardelli, M.
10.1101/2023.03.02.530865 — genetics — Posted on 2023-03-07
3655 Spatial positioning of preimplantation mouse embryo blastomeres is regulated by mTORC1 and 7mG-cap dependent translation at the 8- to 16-cell transition.
Gahurova, L.; Tomankova, J.; Cerna, P.; Bora, P.; Kubickova, M.; Virnicchi, G.; Kovacicova, K.; Potesil, D.; Hruska, P.; Zdrahal, Z.; Anger, M.; Susor, A.; Bruce, A. W.
10.1101/2023.03.07.531473 — developmental biology — Posted on 2023-03-07
3656 Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice
Maniou, E.; Farah, F.; Crane-Smith, Z.; Krstevski, A.; Stathopoulou, A.; Greene, N. D.; Copp, A. J.; Galea, G. L.
10.1101/2023.03.07.531511 — developmental biology — Posted on 2023-03-07
3657 Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells
Yang, X.; Smith, J. L.; Beck, M. T.; Wilkinson, J. M.; Michaud, A.; Vasta, J. D.; Robers, M. B.; Willson, T. M.
10.1101/2023.02.25.529946 — cell biology — Posted on 2023-03-07
3658 Accelerating the clock: Interconnected speedup of energetic and molecular dynamics during aging in cultured human cells
Sturm, G.; Bobba-Alves, N.; Tumasian, R. A.; Michelson, J.; Ferrucci, L.; Kempes, C. P.; Picard, M.
10.1101/2022.05.10.491392 — cell biology — Posted on 2023-03-07
3660 The immediate early protein 1 of human herpesvirus 6B counteracts ATM activation in an NBS1-dependent manner
Collin, V.; Biquand, E.; Tremblay, V.; Lavoie, E. G.; Dessapt, J.; Blondeau, A.; Gravel, A.; Flamand, L.; Fradet-Turcotte, A.
10.1101/2021.07.31.454588 — microbiology — Posted on 2023-03-07
3661 Comparative genomics and transcriptomic response to root exudates of six rice root-associated Burkholderia sensu lato species
Wallner, A.; Klonowska, A.; Guigard, L.; King, E.; Rimbault, I.; Ngonkeu, E. L.; Nguyen, P. V.; Bena, G.; Moulin, L.
10.1101/2022.10.04.510755 — microbiology — Posted on 2023-03-07
3662 Event-related modulation of alpha rhythm explains the auditory P300 evoked response in EEG
Studenova, A. A.; Forster, C.; Engemann, D. A.; Hensch, T.; Sander, C.; Mauche, N.; Hegerl, U.; Loeffler, M.; Villringer, A.; Nikulin, V. V.
10.1101/2023.02.20.529191 — neuroscience — Posted on 2023-03-07
3664 Insula dynorphin and kappa opioid receptor systems regulate alcohol drinking in a sex-specific manner in mice
Pina, M.; Pati, D.; Neira, S.; Taxier, L. R.; Stanhope, C.; Mahoney, A.; D'Ambrosio, S.; Kash, T. L.; Navarro, M.
10.1101/2021.11.09.467893 — neuroscience — Posted on 2023-03-07
3667 Targeting the Cx26/NANOG/Focal Adhesion Kinase Complex via Cell Penetrating Peptides in Triple Negative Breast Cancers
Mulkearns-Hubert, E. E.; Esakov, E.; Ben-Salem, S.; Bharti, R.; Hajdari, N.; Johnson, S.; Myers, A.; Smith, I. N.; Bandyopadhyay, S.; Eng, C.; Downs-Kelly, E.; Lathia, J.; Reizes, O.
10.1101/2021.09.09.459689 — cancer biology — Posted on 2023-03-07
3668 Discovery of long non-coding RNAs in the liver fluke, Fasciola hepatica
McVeigh, P.; McCammick, E.; Robb, E.; Brophy, P.; Morphew, R. M.; Marks, N.; Maule, A.
10.1101/2023.03.07.531498 — genomics — Posted on 2023-03-07
3674 A novel role of macrophage PIST protein in regulating Leishmania major infection
Banerjee, S.; Gadpayle, M. P.; Das, S.; Samanta, S.; Datta, R.; MAITI, S.
10.1101/2023.03.06.531336 — cell biology — Posted on 2023-03-07
3675 Localisation and tissue tropism of the symbiont Microsporidia MB in the germ line and somatic tissues of Anopheles arabiensis
Onchuru, T. O.; Makhulu, E. E.; Herren, J. K.; Koekemoer, L.; Gichuhi, J.; Muthoni, J. N.; Wairimu, A. W.; Otieno, F. G.
10.1101/2023.03.06.531457 — microbiology — Posted on 2023-03-07
3679 A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane of trypanosomes
Gerber, M.; Suppanz, I.; Oeljeklaus, S.; Niemann, M.; Kaser, S.; Warscheid, B.; Schneider, A.; Dewar, C. E.
10.1101/2023.03.07.531462 — biochemistry — Posted on 2023-03-07
3680 The role of glutathione in periplasmic redox homeostasis and oxidative protein folding in Escherichia coli
Knoke, L. R.; Zimmermann, J.; Lupilov, N.; Schneider, J. F.; Celebi, B.; Morgan, B.; Leichert, L. I.
10.1101/2023.03.07.531512 — biochemistry — Posted on 2023-03-07
3681 Uracil Repair - A Source of DNA Glycosylase Dependent Genome Instability
Krawczyk, C.; Bentele, M.; Latypov, V.; Woolcock, K.; Noreen, F.; Fritsch, O.; Schaer, P. L.
10.1101/2023.03.07.530818 — genetics — Posted on 2023-03-07
3684 TAD Evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function
Okhovat, M.; VanCampen, J.; Lima, A. C.; Nevonen, K.; Layman, C. E.; Ward, S.; Herrera, J.; Stendahl, A. M.; Yang, R.; Harshman, L.; Li, W.; Sheng, R. R.; Mao, Y.; Fedorov, L.; Ndjamen, B.; Vigh-Conrad, K. A.; Matthews, I. R.; Easow, S. A.; Chan, D. K.; Jan, T. A.; Eichler, E. E.; Rugonyi, S.; Conrad, D. F.; Ahituv, N.; Carbone, L.
10.1101/2023.03.07.531534 — evolutionary biology — Posted on 2023-03-07
3688 The nucleolar aberrancies that drive ribosome impairment induced by RNA binding proteins are hallmarks of aging
Aguilar-Garrido, P.; Velasco-Estevez, M.; Navarro-Aguadero, M. A.; Hernandez-Sanchez, M.; Malaney, P.; Zhang, X.; Aitken, M. J. L.; Otero-Sobrino, A.; Ibanez-Navarro, M.; Ortiz-Ruiz, A.; Megias, D.; Perez-Martinez, M.; Mata, G.; Gomez, J.; Dominguez, O.; Grana-Castro, O.; Caleiras, E.; de Andres, P. J.; Rodriguez, S.; Torres, R.; Sirozh, O.; Lafarga, V.; Martinez-Lopez, J.; Post, S. M.; Gallardo, M.
10.1101/2023.03.07.531270 — molecular biology — Posted on 2023-03-07
3690 ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins
Mas, A. M.; Goni, E.; Ruiz de los Mozos, I.; Arcas, A.; Statello, L.; Gonzalez, J.; Blazquez, L.; Lee, W. T. C.; Gupta, D.; Sejas, A.; Hoshina, S.; Armaos, A.; Tartaglia, G. G.; Waga, S.; Ule, J.; Rothenberg, E.; Gomez, M.; Huarte, M.
10.1101/2023.03.07.531515 — molecular biology — Posted on 2023-03-07
3692 Bacterial cGAS senses a viral RNA to initiate immunity
Banh, D. V.; Roberts, C. G.; Amador, A. M.; Brady, S. F.; Marraffini, L. A.
10.1101/2023.03.07.531596 — microbiology — Posted on 2023-03-07
3694 A host recognition module shared among distant Alteromonas bacteriophage families features tail fibers with transient chaperone caps
Gonzalez-Serrano, R.; Rosselli, R.; Roda-Garcia, J. J.; Martin-Cuadrado, A.-B.; Rodriguez-Valera, F.; Dunne, M.
10.1101/2023.03.07.531524 — microbiology — Posted on 2023-03-07
3695 An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2
Harvest, C. K.; Abele, T. J.; Yu, C.; Beatty, C. J.; Amason, M. E.; Billman, Z. P.; DePrizio, M. A.; Lacey, C. A.; Maltez, V. I.; Larson, H. N.; McGlaughon, B. D.; Montgomery, S. A.; Miao, E. A.
10.1101/2023.03.07.531568 — immunology — Posted on 2023-03-07
3697 ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation
Du, G.; Healy, L. B.; David, L.; Walker, C.; Fontana, P.; Dong, Y.; Devant, P.; Puthenveetil, R.; Ficarro, S. B.; Banerjee, A.; Kagan, J. C.; Lieberman, J.; Wu, H.
10.1101/2023.03.07.531538 — immunology — Posted on 2023-03-07
3701 Deciphering dermal fibroblast behavior in 3D bioprinted dermis contructs
chastagnier, L.; essayan, L.; courtial, e. j.; Marquette, C.; thomann, c.; PETIOT, E.; el-Kholti, N.
10.1101/2023.03.07.531460 — bioengineering — Posted on 2023-03-07
3702 Development of Fully Human, Bispecific Antibodies that Effectively Block Omicron Variant Pseudovirus Infections
Allen, J. K.; Gonzalez, M. A.; Kaur, J.; Smith, M.; You, J.; Yang, G.; Zha, D.; Tian, Z.; Al-Shami, A.; Shi, C.; Molldrem, J. J.; Heffernan, T.
10.1101/2023.03.07.531527 — biochemistry — Posted on 2023-03-07
3703 O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology
Balana, A. T.; Mahul-Mellier, A.-L.; Nguyen, B. A.; Javed, A.; Hard, E. R.; Jasiqi, Y.; Singh, P.; Pedretti, R.; Singh, V.; Lee, V. M.-Y.; Luk, K. C.; Lashuel, H. R.; Pratt, M. R.
10.1101/2023.03.07.531573 — biochemistry — Posted on 2023-03-07
3704 Calorie Restriction activates a gastric Notch-FOXO1 pathway to expand Ghrelin cells
McKimpson, W. M.; Spiegel, S.; Mukhanova, M.; Kraakman, M.; Du, W.; Kitamoto, T.; Yu, J.; Pajvani, U.; Accili, D.
10.1101/2023.03.06.531352 — cell biology — Posted on 2023-03-07
3705 Cryo-electron tomography sheds light on the elastic nature of the Trypanosoma brucei tripartite attachment complex
Bregy, I.; Radecke, J.; Noga, A.; van den Hoek, H.; Kern, M.; Haenni, B.; Engel, B. D.; Siebert, C. A.; Ishikawa, T.; Zuber, B.; Ochsenreiter, T.
10.1101/2023.03.06.531305 — cell biology — Posted on 2023-03-07
3706 Single-Cell Map of Dynamic Multicellular Ecosystem of Radiation-Induced Intestinal Injury
Yan, H.; Lu, H.; Xing, Y.; Ye, Y.; Jiang, S.; Ma, L.; Zuo, H.; Hao, Y.; Yu, C.; Li, Y.; Lu, Y.; Zhou, G.
10.1101/2023.03.06.531402 — cell biology — Posted on 2023-03-07
3708 Multicellular dynamics on 3D scaffolds: Stress concentration is a key to controlling complex microtissue morphology on engineered surfaces
Matsuzawa, R.; Matsuo, A.; Fukamachi, S.; Takeuchi, M.; Nishina, T.; Kollmannsberger, P.; Sudo, R.; Okuda, S.; Yamashita, T.
10.1101/2023.03.06.530721 — biophysics — Posted on 2023-03-07
3715 Matrix and analysis metadata standards (MAMS) to facilitate harmonization and reproducibility of single-cell data
Wang, Y.; Sarfraz, I.; Teh, W. K.; Sokolov, A.; Herb, B. R.; Creasy, H. H.; Virshup, I.; Dries, R.; Degatano, K.; Mahurkar, A.; Schnell, D. J.; Madrigal, P.; Hilton, J.; Gehlenborg, N.; Tickle, T.; Campbell, J. D.
10.1101/2023.03.06.531314 — bioinformatics — Posted on 2023-03-07
3716 Application of fuzzy measures to move towards the cyber-taxonomy
Ciguene, R. R.; Mozziconacci, J. J.; Clement, F. F.; Miralles, A. A.
10.1101/2023.03.06.531255 — bioinformatics — Posted on 2023-03-07
3717 Morphine Re-arranges Chromatin Spatial Architecture of Primate Cortical Neurons
Wang, L.; Wang, X.; Liu, C.; Xu, W.; Kuang, W.; Bu, Q.; Li, H.; Zhao, Y.; Jiang, L.; Chen, Y.; Qin, F.; Li, S.; Wei, Q.; Liu, X.; Liu, B.; Chen, Y.; Dai, Y.; Wang, H.; Tian, J.; Cao, G.; Zhao, Y.; Cen, X.
10.1101/2023.03.06.531278 — bioinformatics — Posted on 2023-03-07
3718 Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma
Samuel, R. M.; Navickas, A.; Maynard, A.; Gaylord, E. A.; Garcia, K.; Bhat, S.; Majd, H.; Richter, M. N.; Elder, N.; Le, D.; Nguyen, P.; Shibata, B.; Losa Llabata, M.; Selleri, L.; Laird, D. J.; Darmanis, S.; Goodarzi, H.; Fattahi, F.
10.1101/2023.03.06.531220 — developmental biology — Posted on 2023-03-07
3719 High Maternal Adiposity During Pregnancy Programs an Imbalance in the Lipidome and Predisposes to Diet-induced Hepatosteatosis in the Offspring
Scheidl, T.; Wager, J.; Baker, L.; Brightwell, A.; Melan, K.; Larion, S.; Sarr, O.; Regnault, T.; Urbanski, S.; Thompson, J.
10.1101/2023.03.06.531438 — developmental biology — Posted on 2023-03-07
3720 Loss of kinase Atg1 increases yeast maintenance energy requirement
Chen, X.; van Aalst, A. C. A.; Petranovic, D.; Bisschops, M. M. M.
10.1101/2023.03.06.531285 — cell biology — Posted on 2023-03-07
3722 Atherosclerosis is a smooth muscle cell-driven tumor-like disease
Pan, H.; Ho, S. E.; Xue, C.; Cui, J.; Ross, L. S.; Li, F.; Solomon, R. A.; Connolly, E. S.; Reilly, M. P.
10.1101/2023.03.06.531330 — cell biology — Posted on 2023-03-07
3729 Brassinosteroid receptor BRL3 triggers systemic plant adaptation to elevated temperature from the phloem cells
Gupta, A.; Medina, A. R.; Elena, F. L.; Bueno, M. M.; Fontanet, J. B.; Fabregas, N.; Alseekh, S.; Fernie, A. R.; Cano-Delgado, A. I.
10.1101/2023.03.07.531487 — plant biology — Posted on 2023-03-07
3730 Fagalean phylogeny in a nutshell: Chronicling the diversification history of Fagales
Siniscalchi, C. M.; Correa-Narvaez, J.; Kates, H. R.; Soltis, D. E.; Soltis, P. S.; Guralnick, R. P.; Manchester, S. R.; Folk, R. A.
10.1101/2023.03.06.531381 — plant biology — Posted on 2023-03-07
3731 Roles of microbiota in autoimmunity in Arabidopsis
Cheng, Y. T.; Thireault, C. A.; Paasch, B. C.; Zhang, L.; He, S. Y.
10.1101/2023.03.06.531303 — plant biology — Posted on 2023-03-07
3734 A rapid method to quantify vein density in C4 plants using starch staining
Simpson, C. J.; Singh, P.; Sogbohossou, D. E.; Schranz, M. E.; Hibberd, J. M.
10.1101/2023.03.06.531345 — plant biology — Posted on 2023-03-07
3735 An improved Nicotiana benthamiana bioproduction chassis provides novel insights into nicotine biosynthesis
Vollheyde, K.; Dudley, Q. M.; Yang, T.; Oz, M. T.; Mancinotti, D.; Fedi, M. O.; Heavens, D.; Linsmith, G.; Chhetry, M.; Smedley, M. A.; Harwood, W. A.; Swarbreck, D.; Geu-Flores, F.; Patron, N.
10.1101/2023.03.06.531326 — plant biology — Posted on 2023-03-07
3738 Diatom adhesive trail proteins acquired by horizontal gene transfer from bacteria serve as primers for marine biofilm formation
Zackova Suchanova, J.; Bilcke, G.; Romanowska, B.; Fatlawi, A.; Pippel, M.; Skeffington, A.; Schroeder, M.; Vyverman, W.; Vandepoele, K.; Kroeger, N.; Poulsen, N.
10.1101/2023.03.06.531300 — plant biology — Posted on 2023-03-07
3739 CRISPRa-induced upregulation of human LAMA1 compensates for LAMA2-deficiency in Merosin-deficient congenital muscular dystrophy
Arockiaraj, A. I.; Johnson, M. A.; Munir, A.; Ekambaram, P.; Lucas, P. C.; Mcallister-Lucas, L.; Kemaladewi, D. U.
10.1101/2023.03.06.531347 — genetics — Posted on 2023-03-07
3742 The commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces B cell-modulated remodeling of the gut microbiota
Popovic, A.; Cao, E. Y.; Han, J.; Nursimulu, N.; Alves-Ferreira, E. V. C.; Kennard, A.; Alsmadi, N.; Grigg, M. E.; Mortha, A.; Parkinson, J.
10.1101/2023.03.06.528774 — microbiology — Posted on 2023-03-07
3743 Mechanical transmission of Dengue Virus by Aedes aegypti may influence disease transmission dynamics during outbreaks
Li, H.-H.; Su, M. P.; Wu, S.-C.; Tsou, H.-H.; Chang, M.-C.; Cheng, Y.-C.; Tsai, K.-N.; Wang, H.-W.; Chen, G.-H.; Tang, C.-K.; Chung, P.-J.; Tsai, W.-T.; Huang, L.-R.; Yueh, Y. A.; Chen, H.-W.; Pan, C.-Y.; Akbari, O.; Chang, H.-H.; Yu, G.-Y.; Marshall, J. M.; CHEN, C.-H.
10.1101/2023.03.07.531453 — microbiology — Posted on 2023-03-07
3744 A systematic review on leptospirosis in cattle: a European perspective
Sohm, C.; Steiner, J.; Jöbstl, J.; Wittek, T.; Firth, C.; Steinparzer, R.; Desvars-Larrive, A.
10.1101/2023.03.07.531463 — microbiology — Posted on 2023-03-07
3746 Neutrophil efferocytosis reprograms mitochondrial metabolism to switch alveolar macrophages to a pro-resolution phenotype at the cost of bacterial control
Better, J.; Wetstein, M.; Estiri, M.; Malainou, C.; Ferrero, M.; Langelage, M.; Kuznetsova, I.; Vazquez-Armendariz, I.; Kimmig, L.; Mansouri, S.; Savai, R.; Wilhelm, J.; Alexopoulos, I.; Sommer, N.; Herold, S.; Matt, U.
10.1101/2023.03.07.528464 — immunology — Posted on 2023-03-07
3748 An Anti-diabetic Nutraceutical enhances muscle cell glucose uptake of cardiometabolic drugs
K, S.; RN, A. R.; Battula, S.; Mehta, I.; Kadiyala, G.; Iyer, S.; Vangala, S.; Chandran, S.; Saxena, U.
10.1101/2023.03.04.531136 — pharmacology and toxicology — Posted on 2023-03-07
3749 Genome-scale CRISPR-Cas9 screen identifies novel host factors as potential therapeutic targets for SARS-CoV-2 infection.
Sakai, M.; Masuda, Y.; Tarumoto, Y.; Aihara, N.; Tsunoda, Y.; Iwata, M.; Kamiya, Y.; Komorizono, R.; Noda, T.; Yusa, K.; Tomonaga, K.; Makino, A.
10.1101/2023.03.06.531431 — microbiology — Posted on 2023-03-07
3753 Alternative splicing of the stress-sensitive regulator CIRBP sharpens the cellular response to bacterial infection
Corre, M.; Boehm, V.; Besic, V.; Kurowska, A.; Viry, A.; Mohammad, A.; Senamaud-Beaufort, C.; Thomas-Chollier, M.; Lebreton, A.
10.1101/2023.01.18.524578 — molecular biology — Posted on 2023-03-07
3757 A Chromosome-Level Genome Assembly for the Rock Ptarmigan (Lagopus muta)
Rodin Morch, P. E.; Squires, T. E.; Formenti, G.; Tracey, A.; Abueg, L. A.; Brajuka, N.; Jarvis, E. D.; Melsted, P.; Höglund, J.; Magnusson, K. P.
10.1101/2023.01.31.526508 — molecular biology — Posted on 2023-03-07
3759 The iron-dopamine D1 coupling modulates neural signatures of working memory across adult lifespan
Gustavsson, J.; Johansson, J.; Falahati, F.; Andersson, M.; Papenberg, G.; Avelar-Pereira, B.; Bäckman, L.; Kalpouzos, G.; Salami, A.
10.1101/2023.02.09.527840 — neuroscience — Posted on 2023-03-07
3762 Unravelling the anticancer and enzyme inhibition potential of different classes of compounds including a new steroid, isolated from Cassia mimosoïdes
Tchebou, R. V. K.; Farooq, U.; Khan, S.; Rasool, A.; Sarwar, R.; Khushal, A.; Tapondjou, L. A.; Bukhari, S. M.; Teponno, R. B.
10.1101/2023.03.05.531233 — biochemistry — Posted on 2023-03-07
3763 Intra and interspecific diversity in a tropical plant clade alter herbivory and ecosystem resilience
Grele, A.; Massad, T. J.; Uckele, K. A.; Dyer, L.; Antonini, Y.; Braga, L.; Forister, M. L.; Sulca-Garro, L.; Kato, M.; Lopez, H. G.; Nascimento, A. R.; Parchman, T.; Simbana, W. R.; Smilanich, A. M.; Stireman, J. O.; Tepe, E. J.; Walla, T.; Richards, L. A.
10.1101/2023.03.05.531210 — ecology — Posted on 2023-03-07
3766 Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zone
Morrison, V. E.; Houpert, M. G.; Trapani, J. B.; Brockman, A.; Kingsley, P. J.; Katdare, K. A.; Layden, H. M.; Nguena-Jones, G. N.; Trevisan, A. J.; Maguire-Zeiss, K. A.; Marnett, L. J.; Bix, G.; Ihrie, R. A.; Carter, B. D.
10.1101/2023.03.03.531012 — neuroscience — Posted on 2023-03-07
3767 Induction of T-DNA amplification by retrotransposon-derived sequences
Dickinson, L.; Yuan, W.; LeBlanc, C.; Thomson, G.; Wang, S.; Jacob, Y.
10.1101/2023.03.05.531200 — plant biology — Posted on 2023-03-07
3768 Long noncoding RNA-mediated epigenetic regulation of auxin-related genes controlling shade avoidance syndrome in Arabidopsis thaliana
Mammarella, M. F.; Lucero, L.; Hussain, N.; Munoz-Lopez, A.; Huang, Y.; Ferrero, L.; Fernandez-Milmanda, G.; Manavella, P. A.; Benhamed, M.; Crespi, M.; Ballare, C.; Gutierrez-Marcos, J.; Cubas, P.; Ariel, F.
10.1101/2023.03.06.531280 — plant biology — Posted on 2023-03-07
3769 Functional Ambidexterity of an Ancient Nucleic Acid-Binding Domain
Weil-Ktorza, O.; Fridmann-Sirkis, Y.; Despotovic, D.; Naveh-Tassa, S.; Levy, Y.; Metanis, N.; Longo, L. M.
10.1101/2023.03.06.531422 — biophysics — Posted on 2023-03-07
3770 DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity
Ryder, B. D.; Boyer, D. R.; Ustyantseva, E.; Mendoza-Oliva, A.; Kuska, M.; Wydorski, P. M.; Sawaya, M.; Diamond, M. I.; Eisenberg, D.; Kampinga, H. H.; Joachimiak, L. A.
10.1101/2023.03.06.531355 — biophysics — Posted on 2023-03-07
3771 Structure-Kinetics Relationships of Opioids from Metadynamics and Machine Learning
Mahinthichaichan, P.; Liu, R.; Vo, Q. N.; Ellis, C. R.; Stavitskaya, L.; Shen, J.
10.1101/2023.03.06.531338 — biophysics — Posted on 2023-03-07
3774 Frameshift Mutations in the Microevolution and Macroevolution of Viruses
Yufei, J.; Jianwei, S.; Ruixu, C.; Huanyu, G.; Minghui, S.; Guohui, L.; Chen, J.-M.
10.1101/2022.07.20.500745 — evolutionary biology — Posted on 2023-03-06
3775 Comparison Between Gradients and Parcellations for Functional Connectivity Prediction of Behavior
Kong, R.; Tan, Y. R.; Wulan, N.; Ooi, L. Q. R.; Farahibozorg, S.-R.; Harrison, S.; Bijsterbosch, J. D.; Bernhardt, B. C.; Eickhoff, S.; Yeo, B. T. T.
10.1101/2022.09.22.509045 — neuroscience — Posted on 2023-03-06
3777 FMRP regulates postnatal neuronal migration via MAP1B
Messaoudi, S.; Stoufflet, J.; Fouquet, C.; Doulazmi, M.; Allam, A.; Paillard, T.; Trembleau, A.; Caille, I.
10.1101/2023.03.06.530447 — neuroscience — Posted on 2023-03-06
3780 Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments.
Ogawa, Y.; Lim, B.; George, S.; Oses-Prieto, J.; Rasband, J.; Eshed-Eisenbach, Y.; Nair, S.; Boata, F.; Peles, E.; Burlingame, A.; Van Aelst, L.; Rasband, M. N.
10.1101/2023.03.06.531378 — neuroscience — Posted on 2023-03-06
3781 High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators of HOX/MEIS Activation in Acute Myeloid Leukemia
Barbosa, K.; Deshpande, A.; Perales, M. E.; Xiang, P.; Murad, R.; Minkina, A.; Robertson, N. A.; Schischlik, F.; Lei, X.; Sun, Y.; Brown, A.; Amend, D.; Jeremias, I.; Doench, J. G.; Humphries, K.; Ruppin, E.; Shendure, J.; Mali, P.; Adams, P. D.; Deshpande, A. J.
10.1101/2022.12.12.519332 — cancer biology — Posted on 2023-03-06
3787 A chromosome-assigned Mongolian gerbil genome with sequenced centromeres provides evidence of a new chromosome
Brekke, T. D.; Papadopulos, A. S.; Julia, E.; Fornas, O.; Fu, B.; Yang, F.; de la Fuente, R.; Page, J.; Baril, T.; Hayward, A.; Mulley, J.
10.1101/2022.09.21.508825 — genomics — Posted on 2023-03-06
3788 Discovery of NRG1-VII: a novel myeloid-derived class of NRG1 isoforms
Angel Berrocal-Rubio, M.; Prawer, Y. D. J.; Dinevska, M.; De Paoli-Iseppi, R.; Widodo, S. S.; Rajab, N.; De Nardo, W.; Hallab, J. C.; Li, A.; Mantamadiotis, T.; Clark, M.; Wells, C.
10.1101/2023.02.02.525781 — genomics — Posted on 2023-03-06
3791 Stochastic dispersal assembly dominates tropical invertebrate community assembly regardless of land use intensity
Granville, N. R.; Barclay, M. V. L.; Boyle, M. J. W.; Chung, A. Y. C.; Fayle, T. M.; Hah, H. E.; Hardwick, J. L.; Kinneen, L.; Kitching, R. L.; Maunsell, S. C.; Miller, J. A.; Sharp, A. C.; Stork, N. E.; Wai, L.; Yusah, K. M.; Ewers, R. M.
10.1101/2023.01.30.526177 — ecology — Posted on 2023-03-06
3793 Identification of unique α4 chain structure and conserved anti-angiogenic activity of α3NC1 type IV collagen in zebrafish
LeBleu, V. S.; Dai, J.; Tsutakawa, S.; MacDonald, B. A.; Alge, J. L.; Sund, M.; Xie, L.; Sugimoto, H.; Tainer, J.; Zon, L. I.; Kalluri, R.
10.1101/2022.08.14.503918 — developmental biology — Posted on 2023-03-06
3794 Sfrp2 is a multifunctional regulator of rodent color patterns
Johnson, M. R.; Li, S.; Guerrero-Juarez, C. F.; Miller, P.; Brack, B. J.; Mereby, S.; Feigin, C. Y.; Gaska, J.; Ploss, A.; Nie, Q.; Rivera-Perez, J. A.; Shvartsman, S. Y.; Mallarino, R.
10.1101/2022.12.12.520043 — developmental biology — Posted on 2023-03-06
3798 Programmed cell death improves sustainability of phycocyanin production from cyanobacteria
Zorz, J.; Paquette, A. J.; Gillis, T.; Kouris, A.; Khot, V.; Demirkaya, C.; De La Hoz Siegler, H.; Strous, M.; Vadlamani, A.
10.1101/2022.10.17.512555 — microbiology — Posted on 2023-03-06
3799 Virus diversity and activity is driven by snowmelt and host dynamics in a high-altitude watershed soil ecosystem
coclet, c.; Sorensen, P. O.; Karaoz, U.; Wang, S.; Brodie, E. L.; Eloe-Fadrosh, E. A. A.; Roux, S.
10.1101/2023.03.06.531389 — microbiology — Posted on 2023-03-06
3800 Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis in mice
Wynn, E. A.; Dide-Agossou, C.; Reichlen, M.; Rossmassler, K.; Al Mubarak, R.; Reid, J. J.; Tabor, S. T.; Born, S. E.; Ransom, M. R.; Davidson, R. M.; Walton, K. N.; Benoit, J. B.; Bauman, A. A.; Massoudi, L. M.; Dolganov, G.; Nahid, P.; Voskuil, M. I.; Robertson, G. T.; Moore, C. M.; Walter, N. D.
10.1101/2023.03.06.531356 — microbiology — Posted on 2023-03-06
3801 An IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich microenvironment in multiple myeloma
de Jong, M. M.; Fokkema, C.; Papazian, N.; van Heusden, T.; Vermeulen, M.; Hoogenboezem, R.; van Beek, G.; Tahri, S.; Sanders, M. A.; van de Woestijne, P.; Gay, F.; Moreau, P.; Büttner-Herold, M.; Bruns, H.; van Duin, M.; Broijl, A.; Sonneveld, P.; Cupedo, T.
10.1101/2023.03.03.530773 — immunology — Posted on 2023-03-06
3802 Metastatic infiltration of nervous tissue and periosteal nerve sprouting in multiple myeloma induced bone pain
Diaz-delCastillo, M.; Palasca, O.; Nemler, T. T.; Thygesen, D. M.; Chavez-Saldana, N. A.; Vazquez-Mora, J. A.; Ponce Gomez, L. Y.; Juhl Jensen, L.; Evans, H.; Andrews, R. E.; Mandal, A.; Neves, D.; Mehlen, P.; Caruso, J. P.; Dougherty, P. M.; Price, T. J.; Chantry, A.; Lawson, M. A.; Andersen, T. L.; Jimenez-Andrade, J. M.; Heegaard, A.-M.
10.1101/2022.12.29.522199 — neuroscience — Posted on 2023-03-06
3804 Lysergic Acid Diethylamide Alters the Effects of Brain Stimulation in Rodents
Dwiel, L.; Henricks, A. M.; Bragg, E.; Nicol, J.; Gui, J.; Doucette, W.
10.1101/2022.10.31.514588 — neuroscience — Posted on 2023-03-06
3806 Scn1a-GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neurons
Yamagata, T.; Ogiwara, I.; Tatsukawa, T.; Suzuki, T.; Otsuka, Y.; Imaeda, N.; Mazaki, E.; Inoue, I.; Tokonami, N.; Hibi, Y.; Itohara, S.; Yamakawa, K.
10.1101/2021.03.31.437794 — neuroscience — Posted on 2023-03-06
3807 Unsupervised decomposition of natural monkey behavior into a sequence of motion motifs
Mimura, K.; Matsumoto, J.; Mochihashi, D.; Nakamura, T.; Nishijo, H.; Higuchi, M.; Hirabayashi, T.; Minamimoto, T.
10.1101/2023.03.04.531044 — neuroscience — Posted on 2023-03-06
3808 State-dependent effectiveness of cathodal transcranial direct current stimulation on cortical excitability
Vergallito, A.; Varoli, E.; Pisoni, A.; Mattavelli, G.; Del Mauro, L.; Feroldi, S.; Vallar, G.; Romero Lauro, L. J.
10.1101/2023.03.03.531020 — neuroscience — Posted on 2023-03-06
3809 Relationship Between Prediction Accuracy and Feature Importance Reliability: an Empirical and Theoretical Study
Chen, J.; Ooi, L. Q. R.; Tan, T. W. K.; Zhang, S.; Li, J.; Asplund, C. L.; Eickhoff, S. B.; Bzdok, D.; Holmes, A. J.; Yeo, B. T. T.
10.1101/2022.08.08.503167 — neuroscience — Posted on 2023-03-06
3810 Migratory birds are able to choose the appropriate migratory direction under dim yellow monochromatic light
Romanova, N.; Utvenko, G.; Prokshina, A.; Cellarius, F.; Fedorischeva, A.; Pakhomov, A.
10.1101/2023.01.13.523666 — zoology — Posted on 2023-03-06
3814 A happy accident: a novel turfgrass reference genome
Phillips, A. R.; Seetharam, A. S.; Albert, P. S.; AuBuchon-Elder, T.; Birchler, J. A.; Buckler, E. S.; Gillespie, L. J.; Hufford, M. B.; Llaca, V.; Romay, M. C.; Soreng, R. J.; Kellogg, E. A.; Ross-Ibarra, J.
10.1101/2022.03.08.483531 — plant biology — Posted on 2023-03-06
3818 Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
DeBlasi, J. M.; Falzone, A.; Caldwell, S.; Prieto-Farigua, N.; Prigge, J. R.; Schmidt, E. E.; Chio, I. I. C.; Karreth, F. A.; DeNicola, G. M.
10.1101/2022.08.24.504986 — cancer biology — Posted on 2023-03-06
3822 Pangenome Graph Construction from Genome Alignment with Minigraph-Cactus
Hickey, G.; Monlong, J.; Ebler, J.; Novak, A.; Eizenga, J. M.; Gao, Y.; Human Pangenome Reference Consortium, ; Marschall, T.; Li, H.; Paten, B.
10.1101/2022.10.06.511217 — bioinformatics — Posted on 2023-03-06
3823 A systematic mapping of the genomic and proteomic variation associated with monogenic diabetes
Kuznetsova, K.; Vasicek, J.; Skiadopoulou, D.; Molnes, J.; Udler, M.; Johansson, S.; Njolstad, P. R.; Manning, A. K.; Vaudel, M.
10.1101/2023.01.19.524722 — bioinformatics — Posted on 2023-03-06
3824 ORFanID: A Web-Based Search Engine for the Discovery and Identification of Orphan and Taxonomically Restricted Genes
Gunasekera, R. S.; Raja, K. K. B.; Hewapathirana, S.; Tundrea, E.; Gunasekera, V.; Galbadage, T.; Nelson, P. A.
10.1101/2022.02.01.478498 — bioinformatics — Posted on 2023-03-06
3826 Precise targeting for 3D cryo-correlative light and electron microscopy volume imaging of tissues using a FinderTOP
de Beer, M.; Daviran, D.; Roverts, R.; Rutten, L.; Sanchez, e. M.; Metz, J.; Sommerdijk, n.; Akiva, A.
10.1101/2022.07.31.502212 — cell biology — Posted on 2023-03-06
3828 FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55/PP2A phosphatase
Wasserman, J. S.; Faezov, B.; Patel, K. R.; Kurimchak, A. M.; Palacio, S.; Fowle, H.; McEwan, B. C.; Xu, Q.; Zhao, Z.; Cressey, L.; Johnson, N.; Duncan, J. S.; Kettenbach, A. S.; Dunbrack, R. L.; Grana, X.
10.1101/2023.03.06.531310 — molecular biology — Posted on 2023-03-06
3829 Identification of functional Npu DnaE and gp41-1 inteins split in three fragments
Weis, D.; Palanisamy, N.; Ballestin Ballestin, J.; Oeztuerk, M. A.; Di Ventura, B.
10.1101/2023.01.30.526203 — molecular biology — Posted on 2023-03-06
3830 Engineering and implementation of synthetic molecular tools in the basidiomycete fungus Ustilago maydis
Heucken, N.; Tang, K.; Huesemann, L.; Hessler, N.; Müntjes, K.; Feldbrügge, M.; Göhre, V.; Zurbriggen, M. D.
10.1101/2023.03.06.531311 — microbiology — Posted on 2023-03-06
3832 A thalamic circuit represents dose-like responses induced by nicotine-related beliefs in human smokers
Perl, O.; Shuster, A.; Heflin, M.; Na, S.; Kidwai, A.; Booker, N.; Putnam, W. C.; Fiore, V. G.; Gu, X.
10.1101/2022.07.15.500226 — neuroscience — Posted on 2023-03-06
3833 The role of size in biostability of DNA tetrahedra
Vilcapoma, J.; Patel, A.; Chandrasekaran, A. R.; Halvorsen, K.
10.1101/2023.03.06.531312 — synthetic biology — Posted on 2023-03-06
3834 Preventing production escape during scale-up using an engineered glucose-inducible genetic circuit
Tavares, L. F.; Ribeiro, N. V.; Zocca, V. F. B.; Correa, G. G.; Amorim, L. A. d. S.; Lins, M. R. d. C. R.; Pedrolli, D. B.
10.1101/2023.03.06.530450 — synthetic biology — Posted on 2023-03-06
3835 Potential of Negative Ion Mode Proteomics: MS1-Only Approach
Penanes, P. A.; Gorshkov, V.; Ivanov, M. V.; Gorshkov, M. V.; Kjeldsen, F.
10.1101/2023.03.06.530802 — molecular biology — Posted on 2023-03-06
3838 DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres
Myler, L. R.; Toia, B.; Vaughan, C. K.; Takai, K.; Matei, A. M.; Wu, P.; Paull, T. T.; de Lange, T.; Lottersberger, F.
10.1101/2023.03.06.531339 — molecular biology — Posted on 2023-03-06
3840 Tat-fimbriae ("tafi") - novel type of haloarchaeal surface structures
Galeva, A. V.; Syutkin, A. S.; Zhao, D.; Kireev, I. I.; Surin, A. K.; Pavlova, E. Y.; Liu, J.; Xiang, H.; Pyatibratov, M. G.
10.1101/2023.03.06.531322 — microbiology — Posted on 2023-03-06
3841 The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells
Koch, J.; Xin, Q.; Obr, M.; Schaefer, A.; Rolfs, N.; Anagho, H. A.; Kudulyte, A.; Woltereck, L.; Kummer, S.; Campos, J.; Uckeley, Z. M.; Bell-Sakyi, L.; Kraeusslich, H.-G.; Schur, F. K.; Acuna, C.; Lozach, P.-Y.
10.1101/2023.03.06.531240 — microbiology — Posted on 2023-03-06
3842 Multiplexed Amplicon Sequencing Reveals High Sequence Diversity of Antibiotic Resistance Genes in Quebec Sewers
Gibson, C.; Kraemer, S. A.; Klimova, N.; Vanderweyen, L.; Klai, N.; Diaz Mendoza, E.; Guo, B.; Walsh, D. A.; Frigon, D.
10.1101/2023.03.06.531290 — microbiology — Posted on 2023-03-06
3846 Bioinformatics-Guided Discovery of Biaryl-Tailored Lasso Peptides
Saad, H.; Majer, T.; Bhattarai, K.; Lampe, S.; Nguyen, D. T.; Kramer, M.; Straetener, J.; Broetz-Oesterhelt, H.; Mitchell, D. A.; Gross, H.
10.1101/2023.03.06.531328 — biochemistry — Posted on 2023-03-06
3847 Stuck in the weeds: Invasive grasses reduce tiger snake movement
Cornelis, J.; Cooper, C. E.; Lettoof, D. C.; Mayer, M.; Marshall, B. M.
10.1101/2023.03.06.531246 — ecology — Posted on 2023-03-06
3848 Immunometabolic rewiring in long COVID patients with chronic headache
Foo, S.-S.; Chen, W.; Jung, K. L.; Azamor, T.; Choi, U. Y.; Zhang, P.; Comhair, S. A.; Erzurum, S. C.; Jehi, L.; Jung, J. U.
10.1101/2023.03.06.531302 — microbiology — Posted on 2023-03-06
3853 High-Capacity Sample Multiplexing for Single Cell Chromatin Accessibility Profiling
Booth, G. T.; Daza, R. M.; Srivatsan, S. R.; McFaline-Figueroa, J. L.; Green Gladden, R.; Furlan, S. N.; Shendure, J.; Trapnell, C.
10.1101/2023.03.05.531201 — molecular biology — Posted on 2023-03-06
3857 An Integrative Approach to Dissect the Drug Resistance Mechanism of the H172Y Mutation of SARS-CoV-2 Main Protease
Clayton, J.; de Oliveira, V. M.; Ibrahim, M. F.; Sun, X.; Mahinthichaichan, P.; Shen, M.; Hilgenfeld, R.; Shen, J.
10.1101/2022.07.31.502215 — biochemistry — Posted on 2023-03-06
3858 Endothelial cell-derived lactate triggers mesenchymal stem cell histone lactylation to attenuate osteoporosis
Wu, J.; Hu, M.; Jiang, H.; ma, j.; Xie, C.; Zhang, Z.; Zhou, X.; Zhao, J.; Tao, Z.; Meng, Y.; Cai, Z.; Song, T.; Zhang, C.; Gao, R.; Song, H.; Gao, Y.; Lin, T.; Wang, C.; Zhou, X.
10.1101/2023.03.06.531262 — cell biology — Posted on 2023-03-06
3860 Blood-based genome-wide DNA methylation correlations across body fat and adiposity-related biochemical traits
Hatton, A. A.; Hillary, R. F.; Bernabeu, E.; McCartney, D. L.; Marioni, R. L.; McRae, A. F.
10.1101/2023.03.05.530890 — genomics — Posted on 2023-03-06
3862 Efficient clathrin-mediated entry of enteric adenoviruses in human duodenal cells
Becker, M.; Dorma, N.; Conca, D. V.; Mistry, N.; Bally, M.; Arnberg, N.; Gerold, G.
10.1101/2023.03.06.531250 — microbiology — Posted on 2023-03-06
3863 Functional profiling of the Toxoplasma genome during acute mouse infection
Giuliano, C. J.; Wei, K. J.; Harling, F. M.; Waldman, B. S.; Farringer, M. A.; Boydston, E. A.; Lan, T. C. T.; Thomas, R. W.; Herneisen, A. L.; Sanderlin, A. G.; Coppens, I.; Dvorin, J. D.; Lourido, S.
10.1101/2023.03.05.531216 — microbiology — Posted on 2023-03-06
3864 KSHV uses viral IL6 to expand infected immunosuppressive macrophages
Shimoda, M.; Inagaki, T.; Davis, R. R.; Merleev, A.; Tepper, C.; Maverakis, E. M.; Izumiya, Y.
10.1101/2023.03.05.531224 — immunology — Posted on 2023-03-06
3866 A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
Yao, Z.; van Velthoven, C. T. J.; Kunst, M.; Zhang, M.; McMillen, D.; Lee, C.; Jung, W.; Goldy, J.; Abdelhak, A.; Baker, P.; Barkan, E.; Bertagnolli, D.; Campos, J.; Carey, D.; Casper, T.; Chakka, A. B.; Chakrabarty, R.; Chavan, S.; Chen, M.; Clark, M.; Close, J.; Crichton, K.; Daniel, S.; Dolbeare, T.; Ellingwood, L.; Gee, J.; Glandon, A.; Gloe, J.; Gould, J.; Gray, J.; Guilford, N.; Guzman, J.; Hirschstein, D.; Ho, W.; Jin, K.; Kroll, M.; Lathia, K.; Leon, A.; Long, B.; Maltzer, Z.; Martin, N.; McCue, R.; Meyerdierks, E.; Nguyen, T. N.; Pham, T.; Rimorin, C.; Ruiz, A.; Shapovalova, N.; Slaug
10.1101/2023.03.06.531121 — neuroscience — Posted on 2023-03-06
3867 Social Behavior Atlas: A computational framework for tracking and mapping 3D close interactions of free-moving animals
Han, Y.; Chen, K.; Wang, Y.; Liu, W.; Wang, X.; Liao, J.; Huang, Y.; Han, C.; Huang, K.; Zhang, J.; Cai, S.; Wang, Z.; Wu, Y.; Gao, G.; Wang, N.; Li, J.; Song, Y.; Li, J.; Wang, G.; Wang, L.; Zhang, Y.; Wei, P.; Wei, P.
10.1101/2023.03.05.531235 — neuroscience — Posted on 2023-03-06
3868 Deep neural generation of neuronal spikes.
Nakajima, R.; Shirakami, A.; Tsumura, H.; Matsuda, K.; Nakamura, E.; Shimono, M.
10.1101/2023.03.05.531237 — neuroscience — Posted on 2023-03-06
3874 Cyclic di-GMP interact with putrescine via a PilZ domain receptor YcgR
Gu, W.; Chen, Y.; Chen, Z.; Gao, H.; Xie, C.; Zhang, L.; Liao, L.
10.1101/2023.03.05.531214 — pathology — Posted on 2023-03-06
3875 A conserved microtubule-binding region in Xanthomonas XopL is indispensable for induced plant cell death reactions.
Ortmann, S.; Marx, J.; Lampe, C.; Ehnert, T.-M.; Zinecker, S.; Reimers, M.; Bonas, U.; Erickson, J. L.
10.1101/2023.03.06.531251 — pathology — Posted on 2023-03-06
3876 Cryopreservation and revival of Hawaiian stony corals via isochoric vitrification
Powell-Palm, M. J.; Henley, E. M.; Consiglio, A. N.; Lager, C.; Chang, B.; Perry, R.; Fitzgerald, K.; Daly, J.; Rubinsky, B.; Hagedorn, M.
10.1101/2023.03.05.531199 — biophysics — Posted on 2023-03-06
3877 You can move, but you can't hide: identification of mobile genetic elements with geNomad
Camargo, A. P.; Roux, S.; Schulz, F.; Babinski, M.; Xu, Y.; Hu, B.; Chain, P. S. G.; Nayfach, S.; Kyrpides, N. C.
10.1101/2023.03.05.531206 — bioinformatics — Posted on 2023-03-06
3878 GPU-accelerated Dynamic Time Warping for SelectiveNanopore Sequencing
Sadasivan, H.; Stiffler, D.; Tirumala, A.; Israeli, J.; Narayanasamy, S.
10.1101/2023.03.05.531225 — bioinformatics — Posted on 2023-03-06
3879 Novel crAssphage isolates exhibit conserved gene order and purifying selection of the host specificity protein
Papudeshi, B.; Vega, A. A.; Souza, C.; Giles, S. K.; Mallawaarachchi, V.; Roach, M. J.; An, M.; Jacobson, N.; McNair, K.; Mora, M. F.; Pastrana, K.; Leigh, C.; Cram, C.; Plewa, W. S.; Grigson, S. R.; Bouras, G.; Decewicz, P.; Luque, A.; Droit, L.; Handley, S. A.; Segall, A.; Dinsdale, E. A.; Edwards, R. A.
10.1101/2023.03.05.531146 — bioinformatics — Posted on 2023-03-06
3881 Transdermal Electrophysiological Recordings of Diabetic Peripheral Neuropathy Using a Needle Electrode Array in Mice and Men
Blaszkiewicz, M.; Caron, L.; Villinski, B.; Passarelli, J.; Donnelly, J.; Towne, J. M.; Story, N. M.; Merchant, E.; Khan, F. S.; Emanetoglu, N.; Kass, L.; Smith, R. L.; Townsend, K. L.
10.1101/2023.03.03.530993 — bioengineering — Posted on 2023-03-06
3882 Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice
Meade, R. K.; Long, J. E.; Jinich, A.; Rhee, K. Y.; Ashbrook, D. G.; Williams, R. W.; Sassetti, C. M.; Smith, C. M.
10.1101/2023.03.05.528534 — genetics — Posted on 2023-03-06
3883 Mitochondrial translation regulates terminal erythroid differentiation by maintaining iron homeostasis
Morishima, T.; Fakruddin, M.; Masuda, T.; Wang, Y.; Schoonenberg, V. A. C.; Butter, F.; Arima, Y.; Akaike, T.; Tomizawa, K.; Wei, F.; Suda, T.; Takizawa, H.
10.1101/2023.03.05.531223 — cell biology — Posted on 2023-03-06
3885 Mutations in S2 subunit of SARS-CoV-2 Omicron spike strongly influence its conformation, fusogenicity and neutralization sensitivity
Kumar, S.; Delipan, R.; Chakraborty, D.; Kanjo, K.; Singh, R.; Singh, N.; Siddiqui, S.; Tyagi, A.; Jha, S.; Thakur, K. G.; Pandey, R.; Varadarajan, R.; Ringe, R. P.
10.1101/2023.03.05.531143 — microbiology — Posted on 2023-03-06
3886 Validation of a multiplex microsphere immunoassay for detection of Trypanosoma cruzi antibodies in dogs
Rodriguez, C. A.; Busselman, R. E.; Shen, H.; Saunders, A. B.; Tarleton, R. L.; Hamer, S. A.
10.1101/2023.03.05.531211 — microbiology — Posted on 2023-03-06
3887 The influence of early life exposures on the infant gut virome
Zhang, Y.; Castro-Mejia, J. L.; Deng, L.; Shah, S. A.; Thorsen, J.; Rodriguez, C. L.; Jessen, L. E.; Dion, M. B.; Chawes, B.; Bonnelykke, K.; Sorensen, S. J.; Bisgaard, H.; Moineau, S.; Petit, M.-A.; Stokholm, J.; Nielsen, D. S.
10.1101/2023.03.05.531203 — microbiology — Posted on 2023-03-06
3890 Tau protein aggregation associated with SARS-CoV-2 main protease
Eberle, R. J.; Coronado, M. A.; Gering, I.; Korostov, K.; Stefanski, A.; Stuehler, K.; Kraemer-Schulien, V.; Bloemeke, L.; Bannach, O.; Willbold, D.
10.1101/2023.03.04.531078 — biochemistry — Posted on 2023-03-06
3895 Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types
Agarwal, V.; Inoue, F.; Schubach, M.; Martin, B.; Dash, P.; Zhang, Z.; Sohota, A.; Noble, W.; Yardimci, G.; Kircher, M.; Shendure, J.; Ahituv, N.
10.1101/2023.03.05.531189 — genomics — Posted on 2023-03-06
3896 Phylogenetic analysis shows canine distemper virus outbreak in stray dogs possibly occurs through spillover from wild carnivore reservoirs
Manandhar, P.; Napit, R.; Pradhan, S. M.; Rajbhandari, P. G.; Moravek, J. A.; Joshi, P. R.; Shrestha, R. D.; Karmacharya, D.
10.1101/2023.03.05.531168 — genetics — Posted on 2023-03-06
3898 Seagrass genomes reveal a hexaploid ancestry facilitating adaptation to the marine environment
Ma, X.; Vanneste, S.; Chang, J.; Ambrosino, L.; Barry, K.; Bayer, T.; Bobrov, A. A.; Boston, L.; Campbell, J. E.; Chen, H.; Chiusano, M. L.; Dattolo, E.; Grimwood, J.; He, G.; Jenkins, J.; Khachaturyan, M.; Marin-Guirao, L.; Mesterhazy, A.; Muhd, D.-D.; Pazzaglia, J.; Plott, C.; Rajasekar, S.; Rombauts, S.; Ruocco, M.; Scott, A.; Tan, M. P.; Van de Velde, J.; Vanholme, B.; Webber, J.; Wong, L. L.; Yan, M.; Sung, Y. Y.; Novikova, P.; Schmutz, J.; Reusch, T.; Procaccini, G.; Olsen, J.; Van de Peer, Y.
10.1101/2023.03.05.531170 — evolutionary biology — Posted on 2023-03-06
3901 Novel determinants of NOTCH1 trafficking and signaling in breast epithelial cells
Kobia, F. M.; Castro e Almeida, L.; Carminati, F.; Andronache, A.; Lavezzari, F.; Wade, M.; Vaccari, T.
10.1101/2023.03.05.531156 — cell biology — Posted on 2023-03-06
3904 Working memory-based and -free reward prediction in a dual dopamine system in the basal ganglia
Yoshizawa, T.; Miyamura, Y.; Ochi, Y.; Hira, R.; Funahashi, M.; Sakai, Y.; Cui, Y.; Isomura, Y.
10.1101/2023.03.06.531239 — neuroscience — Posted on 2023-03-06
3906 Traumatic brain injury modifies adult hippocampal neural stem cell fate to promote neurogenesis at the cost of astrogliogenesis.
Bielefeld, P.; Martirosyan, A.; Apresyan, A.; Meerhoff, G.; Pestana, F.; Poovathingal, S.; Reijner, N.; Koning, W.; Clement, R.; van de Veen, I.; Toledo, E.; Dura, I.; Hovhannisyan, S.; Nilges, B.; Bogdoll, A.; Kashikar, N.; Lucassen, P. J.; Belgard, G.; Encinas, J. M.; Holt, M.; Fitzsimons, C. P.
10.1101/2023.03.04.531101 — neuroscience — Posted on 2023-03-06
3908 Ultra-fast micro-CT of an unrestrained live insect
Davranoglou, L.-R.; Mortimer, B.; Schelpuetz, C. M.; Taylor, G. K.
10.1101/2023.03.03.531017 — zoology — Posted on 2023-03-06
3909 Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with impaired kidney function.
Johnson, J. P.; Diener, C.; Levine, A. E.; Wilmanski, T.; Suskind, D. L.; Ralevski, A.; Hadlock, J.; Magis, A. T.; Hood, L.; Rappaport, N.; Gibbons, S. M.
10.1101/2023.03.04.531100 — systems biology — Posted on 2023-03-06
3910 Beyond the Genetic Code: A Tissue Code?
Boman, B. M.; Dinh, T.-N.; Decker, K.; Emerick, B.; Modarai, S.; Opdenaker, L.; Fields, J. Z.; Raymond, C.; Schleiniger, G.
10.1101/2023.03.05.531161 — systems biology — Posted on 2023-03-06
3912 Optimization of somatic embryogenesis in Euterpe edulis Martius using auxin analogs and atomic force microscopy
DE MELLO, T.; Taliuli, Y. d. S.; Silva, T. D.; Zanardo, T. E. C.; Hegedus, C. E. N.; Schmildt, E. R.; Ferreira, A.; Lourenco, M. P.; Pinheiro, P. F.; Aquije, G. M. d. F.; Lopes, J. C.; Otoni, W. C.; Alexandre, R. S.
10.1101/2023.03.04.531114 — plant biology — Posted on 2023-03-06
3914 Genomic resources for a historical collection of cultivated two-row European spring barley genotypes.
Schreiber, M.; Wonneberger, R.; Haaning, A. M.; Coulter, M.; Russell, J.; Himmelbach, A.; Fiebig, A.; Muehlbauer, G. J.; Stein, N.; Waugh, R.
10.1101/2023.03.06.531259 — plant biology — Posted on 2023-03-06
3916 Drought and recovery in barley: key gene networks and retrotransposon response.
Paul, M.; Tanskanen, J.; Jääskeläinen, M.; Chang, W.; Dalal, A.; Moshelion, M.; Schulman, A. H.
10.1101/2023.03.05.531133 — plant biology — Posted on 2023-03-06
3918 Pharmacological characterization of the endocannabinoid sensor GRABeCB2.0
Singh, S.; Sarroza, D.; English, A.; McGrory, M.; Dong, A.; Zweifel, L.; Land, B. B.; Li, Y.; Bruchas, M.; Stella, N.
10.1101/2023.03.03.531053 — pharmacology and toxicology — Posted on 2023-03-06
3919 Relict duck-billed dinosaurs survived into the last age of the dinosaurs in subantarctic Chile
Alarcon-Munoz, J.; Vargas, A. O.; Püschel, H.; Soto-Acuna, S.; Manriquez, L.; Leppe, M.; Kaluza, J.; Milla, V.; Simon-Gutstein, C.; Palma-Liberona, J.; Stinnesbeck, W.; Frey, E.; Pino, J. P.; Bajor, D.; Nunez, E.; Ortiz, H.; Mansilla, H.; Rubilar-Rogers, D.; Cruzado-Caballero, P.
10.1101/2023.03.04.531097 — paleontology — Posted on 2023-03-06
3920 Spatial and temporal transcriptomics of SHH-medulloblastoma with chromothripsis identifies multiple genetic clones that resist to treatment and lead to relapse
Kats, I.; Schreiber, H. S.; Simovic, M.; Sant, P.; Mallm, J.-P.; Li, A.; Velmurugan, P.; Weil, S.; Devens, F.; Sill, M.; Jugold, M.; Moustafa, M.; Abdollahi, A.; Winkler, F.; Korshunov, A.; Pfister, S.; Stegle, O.; Ernst, A.
10.1101/2023.03.03.530989 — cancer biology — Posted on 2023-03-06
3921 Internal Translation of p53 Oncoproteins During Integrated Stress Response Confers Survival Advantage on Cancer Cells
Lopez-Iniesta, M. J.; Lacerda, R.; Ramalho, A. C.; Parkar, S. N.; Marques-Ramos, A.; Pereira, B.; Miyawaki, L.; Fujita, J.; Hrstka, R.; Romao, L.; Candeias, M. M.
10.1101/2023.03.03.531004 — cancer biology — Posted on 2023-03-06
3922 N-MYC regulates Cell Survival via eIF4G1 in inv(16) Acute Myeloid Leukemia
Peramangalam, P. S.; Surapally, S.; Zheng, S.; Burns, R.; Zhu, N.; Rao, S.; Muller-Tidow, C.; Pulikkan, J. A.
10.1101/2023.03.03.531018 — cancer biology — Posted on 2023-03-06
3923 Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction
Vaccaro, K.; Allen, J.; Whitfield, T. W.; Maoz, A.; Reeves, S.; Velarde, J.; Yang, D.; Phan, N.; Bell, G. W.; Hata, A. N.; Weiskopf, K.
10.1101/2023.03.03.531059 — cancer biology — Posted on 2023-03-06
3926 Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Yabo, Y. A.; Moreno-Sanchez, P. M.; Pires-Afonso, Y.; Kaoma, T.; Kyriakis, D.; Grzyb, K.; Poovathingal, S. K.; Poli, A.; Scafidi, A.; Muller, A.; Toth, R.; Oudin, A.; Klink, B.; Berchem, G.; Berthold, C.; Hertel, F.; Mittelbronn, M.; Heiland, D. H.; Skupin, A.; Nazarov, P. V.; Niclou, S. P.; Michelucci, A.; Golebiewska, A.
10.1101/2023.03.05.531162 — cancer biology — Posted on 2023-03-06
3927 Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells
Gu, L.; Zhu, Y.; Lee, M.; Nguyen, A.; Ryujin, N. T.; Huang, J.; Chamseddine, S.; Xiao, L.; Mohamed, Y. I.; Kaseb, A. O.; Karin, M.; Shalapour, S.
10.1101/2023.03.05.531188 — cancer biology — Posted on 2023-03-06
3928 Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer
Mahadevan, K. K.; Dyevoich, A. M.; Chen, Y.; Li, B.; Sugimoto, H.; Sockwell, A. M.; McAndrews, K. M.; Wang, H.; Shalapour, S.; Watowich, S. S.; Kalluri, R.
10.1101/2023.03.05.531191 — cancer biology — Posted on 2023-03-06
3929 Continuous optical detection of small-molecule analytes in complex biomatrices
Hariri, A. A.; Cartwright, A. P.; Dory, C.; Gidi, Y.; Yee, S.; Fu, K. X.; Yang, K.; Wu, D.; Thompson, I. A. P.; Maganzini, N.; Feagin, T.; Young, B. E.; Afshar, B. H.; Eisenstein, M.; Digonnet, M.; Vuckovic, J.; Soh, H. T.
10.1101/2023.03.03.531030 — biophysics — Posted on 2023-03-06
3930 A Slow but Steady NanoLuc: R162A mutation results in a decreased, but stable, NanoLuc activity
Ahmed, W. S.; Geethakumari, A. M.; Sultana, A.; Fatima, A.; Philip, A. M.; Nasiruddin, S. M.; Biswas, K. H.
10.1101/2023.03.05.531182 — biophysics — Posted on 2023-03-06
3932 Cellos: High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology
Mukashyaka, P.; Kumar, P.; Mellert, D. J.; Nicholas, S.; Noorbakhsh, J.; Brugiolo, M.; Anczukow, O.; Liu, E. T.; Chuang, J. H.
10.1101/2023.03.03.531019 — bioinformatics — Posted on 2023-03-06
3939 Targeted Phasing of 2-200 Kilobase DNA Fragments with a Short-Read Sequencer and a Single-Tube Linked-Read Library Method
Mikhaylov, V.; Rzepka, M.; Kawamura, T.; Xia, Y.; Chang, P. L.; Zhou, S.; Pham, L.; Modi, N.; Yao, L.; Perez-Agustin, A.; Pagans, S.; Boles, T. C.; Lei, M.; Wang, Y.; Garcia-Bassets, I.; Chen, Z.
10.1101/2023.03.05.531179 — genomics — Posted on 2023-03-06
3940 Split-Transformer Impute (STI): Genotype Imputation Using a Transformer-Based Model
Mowlaei, M. E.; Li, C.; Chen, J.; Jamialahmadi, B.; Kumar, S.; Rebbeck, T. R.; Shi, X.
10.1101/2023.03.05.531190 — genomics — Posted on 2023-03-06
3942 Medieval social landscape through the genetic history of Cambridgeshire before and after the Black Death
Hui, R.; Scheib, C. L.; D'Atanasio, E.; Inskip, S. A.; Cessford, C.; Biagini, S. A.; Wohns, A. W.; Ali, M. Q. A.; Griffith, S. J.; Solnik, A.; Niinemäe, H.; Ge, X. J.; Rose, A. K.; Beneker, O.; O'Connell, T. C.; Robb, J. E.; Kivisild, T.
10.1101/2023.03.03.531048 — genetics — Posted on 2023-03-06
3943 Ecosystem connectivity and configuration can mediate instability at a distance in metaecosystems
Tadiri, C. P.; Negrin Dastis, J. O.; Cristescu, M.; Gonzalez, A.; Fussmann, G. F.
10.1101/2023.03.03.531041 — ecology — Posted on 2023-03-06
3945 A phylogeny-informed characterization of global tetrapod traits addresses data gaps and biases
Moura, M. R.; Ceron, K.; Guedes, J. J. M.; Sica, Y. V.; Catenazzi, A.; Werneck, F.; Toledo, L. F.; Jetz, W.
10.1101/2023.03.04.531098 — ecology — Posted on 2023-03-06
3946 PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease
Thakore, P.; Yamasaki, E.; Ali, S.; Sanchez Solano, A.; Labelle-Dumais, C.; Gao, X.; Chaumeil, M. M.; Gould, D. B.; Earley, S.
10.1101/2023.03.03.531032 — neuroscience — Posted on 2023-03-06
3947 Delayed formation of neural representations of space in aged mice
McDermott, K. D.; Frechou, M. A.; Jordan, J. T.; Martin, S. S.; Goncalves, J. T.
10.1101/2023.03.03.531021 — neuroscience — Posted on 2023-03-06
3948 State-dependent effectiveness of cathodal transcranial direct current stimulation on cortical excitability
Vergallito, A.; Varoli, E.; Pisoni, A.; Mattavelli, G.; Del Mauro, L.; Feroldi, S.; Vallar, G.; Romero Lauro, L. J.
10.1101/2023.03.03.531020 — neuroscience — Posted on 2023-03-06
3950 Light-Guided Rabies Virus Tracing for Neural Circuit Analysis
Zhang, S.; Ma, Y.; Ngamkanjanarat, W.; Takahashi, S.; Gibbs, D.; Coleman, T.; Doan, S.; Kyriakakis, P.
10.1101/2023.03.04.531104 — neuroscience — Posted on 2023-03-06
3952 Microglia play beneficial roles in multiple experimental seizure models.
Eyo, U. B.; Shelton-Gibbs, S.; Benderoth, J.; Gaykema, R.; Straub, J.; Okojie, K. A.; Uweru, J. O.; Lentferink, D. H.; Rajbanshi, B.; Cowan, M. N.; Patel, B.; Campos-Salazar, A. B.; Perez-Reyes, E.
10.1101/2023.03.04.531090 — neuroscience — Posted on 2023-03-06
3953 L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
Garza, R.; Atacho, D.; Adami, A.; Gerdes, P.; Vinod, M.; Hsieh, P.; Karlsson, O.; Horvath, V.; Johansson, P. A.; Pandiloski, N.; Matas, J.; Quaegebeur, A.; Kouli, A.; Sharma, Y.; Jonsson, M. E.; Monni, E.; Englund, E.; Eichler, E. E.; Gale Hammell, M.; Barker, R. A.; Kokaia, Z.; Douse, C. H.; Jakobsson, J.
10.1101/2023.03.04.531072 — neuroscience — Posted on 2023-03-06
3954 Stress-induced brain responses are associated with BMI in women
Kuehnel, A.; Hagenberg, J.; Knauer-Arloth, J.; Koedel, M.; Czisch, M.; Saemann, P. G.; BeCOME Working Group, ; Binder, E. B.; Kroemer, N. B.
10.1101/2023.03.03.531040 — neuroscience — Posted on 2023-03-06
3955 Eye proteome of Drosophila melanogaster
Kumar, M.; Has, C.; Lam-Kamath, K.; Ayciriex, S.; Dewett, D.; Bashir, M.; Poupault, C.; Schuhmann, K.; Knittelfelder, O.; Raghuraman, B. K.; Ahrends, R.; Rister, J.; Shevchenko, A.
10.1101/2023.03.04.531088 — neuroscience — Posted on 2023-03-06
3959 Chlamydomonas Mutants Null for Chloroplast Triose Phosphate Transporter3 are Metabolically Compromised and Light Sensitive
Huang, W.; Krishnan, A.; Plett, A.; Meagher, M.; Linka, N.; Wang, Y.; Ren, B.; Findinier, J.; Redekop, P.; Fakhimi, N.; Kim, R. G.; Karns, D. A.; Boyle, N.; Posewitz, M.; Grossman, A. R.
10.1101/2022.07.25.501471 — plant biology — Posted on 2023-03-06
3961 Nanothermometry-enabled intelligent laser tissue soldering
Cipolato, O.; Dosnon, L.; Rosendorf, J.; Sarcevic, S.; Bondi, A.; Liska, V.; Schlegel, A.; Herrmann, I. K.
10.1101/2023.03.03.530945 — bioengineering — Posted on 2023-03-06
3968 A role for retro-splenial cortex in the task-related P3 network
Das, D.; Shaw, M. E.; Hamalainen, M. S.; Dykstra, A. R.; Doll, L.; Gutschalk, A.
10.1101/2023.03.03.530970 — neuroscience — Posted on 2023-03-06
3970 Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells
Kirk, J. S.; Wang, J.; Tracz, A.; Long, M.; Rosario, S. R.; Ji, Y.; Kumar, R.; Liu, X.; Singh, P. K.; Puzanov, I.; Chatta, G.; Cheng, Q.; Huang, J.; Wrana, J. L.; Lovell, J.; Yu, H.; Liu, S.; Shen, M. M.; Liu, T.; Tang, D. G.
10.1101/2023.03.03.530998 — cancer biology — Posted on 2023-03-06
3973 Single-cell reference mapping to construct and extend cell type hierarchies
Michielsen, L.; Lotfollahi, M.; Strobl, D.; Sikkema, L.; Reinders, M.; Theis, F. J.; Mahfouz, A.
10.1101/2022.07.07.499109 — bioinformatics — Posted on 2023-03-06
3975 The genome of the toxic invasive species Heracleum sosnowskyi carries an increased number of genes despite the absence of recent whole-genome duplications
Schelkunov, M. I.; Shtratnikova, V. Y.; Klepikova, A. V.; Makarenko, M. S.; Omelchenko, D. O.; Novikova, L. A.; Obukhova, E. N.; Bogdanov, V. P.; Penin, A. A.; Logacheva, M. D.
10.1101/2023.02.14.528432 — genomics — Posted on 2023-03-06
3977 5-iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFkappaB signaling
Chauhan, C.; Kraemer, A.; Knapp, S.; Windheim, M.; Kotlyarov, A.; Menon, M. B.; Gaestel, M.
10.1101/2023.03.03.530727 — cell biology — Posted on 2023-03-06
3980 Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability and Working Memory
Wu, J.; El-Hassar, L.; Datta, D.; Thomas, M.; Zhang, Y.; Jenkins, D. P.; DeLuca, N. J.; Chatterjee, M.; Gribkoff, V. K.; Arnsten, A. F. T.; Kaczmarek, L. K.
10.1101/2023.03.04.529157 — neuroscience — Posted on 2023-03-05
3984 RNA decay defines the therapeutic response to transcriptional perturbation in leukaemia
Todorovski, I.; Feran, B.; Fan, Z.; Gadipally, S.; Yoannidis, D.; Kong, I. Y.; Bjelosevic, S.; Zethoven, M.; Hawkins, E. D.; Simpson, K. J.; Mir Arnau, G.; Papenfuss, A. T.; Johnstone, R. W.; Vervoort, S. J.
10.1101/2022.04.06.487057 — cancer biology — Posted on 2023-03-05
3989 StereoCell enables high accuracy single cell segmentation for spatial transcriptomic dataset
Li, M.; Liu, H.; Li, M.; Fang, S.; Kang, Q.; Zhang, J.; Teng, F.; Wang, D.; Cen, W.; Li, Z.; Feng, N.; Guo, J.; He, Q.; Wang, L.; Zheng, T.; Li, S.; Bai, Y.; Xie, M.; Bai, Y.; Liao, S.; Chen, A.; Xu, X.; Zhang, Y.; Li, Y.
10.1101/2023.02.28.530414 — bioinformatics — Posted on 2023-03-05
3992 Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation
Choi, Y.-M.; Ajjaji, D.; Fleming, K. D.; Borbat, P. P.; Jenkins, M. L.; Moeller, B. E.; Fernando, S.; Bhatia, S. R.; Freed, J. H.; Burke, J. E.; Thiam, A. R.; Airola, M. V.
10.1101/2022.11.17.516819 — biochemistry — Posted on 2023-03-05
3994 Early life exposure to cigarette smoke is associated with lung function changes and primes gene expression and DNA methylation changes at Cyp1a1 upon exposure later in life
Onuzulu, C. D.; Lee, S.; Basu, S.; Comte, J.; Hai, Y.; Hizon, N.; Chadha, S.; Fauni, M. S.; Kahnamoui, S.; Xiang, B.; Halayko, A. J.; Dolinsky, V. W.; Pascoe, C. D.; Jones, M. J.
10.1101/2023.03.03.530858 — genetics — Posted on 2023-03-05
3996 Mutagenic-end joining results in smaller deletions in heterochromatin relative to euchromatin
Miller, J. M.; Prange, S.; Ji, H.; Rau, A. R.; Patel, A.; Butova, N. L.; Lutter, A.; Chung, H.; Merigliano, C.; Rawal, C. C.; Hanscom, T.; McVey, M.; Chiolo, I.
10.1101/2023.03.03.531058 — cell biology — Posted on 2023-03-05
3999 Invasive Californian death caps develop mushrooms unisexually and bisexually
Wang, Y.-W.; McKeon, M. C.; Elmore, H.; Hess, J.; Golan, J.; Gage, H.; Mao, W.; Harrow, L.; Goncalves, S. C.; Hull, C. M.; Pringle, A.
10.1101/2023.01.30.525609 — microbiology — Posted on 2023-03-05
4001 Unsupervised decomposition and description of nonhuman primate behavior
Mimura, K.; Matsumoto, J.; Mochihashi, D.; Nakamura, T.; Nishijo, H.; Higuchi, M.; Hirabayashi, T.; Minamimoto, T.
10.1101/2023.03.04.531044 — neuroscience — Posted on 2023-03-05
4003 The zebrafish mutant dreammist implicates sodium homeostasis in sleep regulation
Barlow, I. L.; Mackay, E.; Wheater, E.; Goel, A.; Lim, S.; Zimmerman, S.; Woods, I.; Prober, D. A.; Rihel, J.
10.1101/2020.11.18.388736 — neuroscience — Posted on 2023-03-05
4005 Wikipedia as a tool for contemporary history of science: A case study on CRISPR
Benjakob, O.; Guley, O.; Sevin, J.-M.; Blondel, L.; Augustoni, A.; Collet, M.; Jouveshomme, L.; Amit, R.; Linder, A.; Aviram, R.
10.1101/2022.11.25.517950 — scientific communication and education — Posted on 2023-03-05
4006 Proteolysis Targeting Chimeras With Reduced Off-targets
Nguyen, T. M.; Sreekanth, V.; Deb, A.; Kokkonda, P.; Tiwari, P. K.; Donovan, K. A.; Shoba, V. M.; Chaudhary, S. K.; Mercer, J. A. M.; Lai, S.; Sadagopan, A.; Jan, M.; Fischer, E. S.; Liu, D. R.; Ebert, B. L.; Choudhary, A.
10.1101/2021.11.18.468552 — pharmacology and toxicology — Posted on 2023-03-05
4007 GoldRush: A de novo long read genome assembler with linear time complexity
Wong, J.; Coombe, L.; Nikolic, V.; Zhang, E.; Nip, K. M.; Sidhu, P.; Warren, R. L.; Birol, I.
10.1101/2022.10.25.513734 — genomics — Posted on 2023-03-05
4008 The motif composition of variable-number tandem repeats impacts gene expression
Lu, T.-Y. T.; Smaruj, P. N.; Fudenberg, G.; Mancuso, N.; Chaisson, M.
10.1101/2022.03.17.484784 — genomics — Posted on 2023-03-05
4010 Predicting predator-prey interactions in terrestrial endotherms using random forest
Llewelyn, J.; Strona, G.; Dickman, C. R.; Greenville, A.; Wardle, G.; Lee, M. S. Y.; Doherty, S.; Shabani, F.; Saltre, F.; Bradshaw, C. J. A.
10.1101/2022.09.02.506446 — ecology — Posted on 2023-03-05
4013 Nodule-specific Cu+-chaperone NCC1 is required for symbiotic nitrogen fixation in Medicago truncatula root nodules
Navarro-Gomez, C.; Leon-Mediavilla, J.; Kupper, H.; Rodriguez-Simon, M.; Paganelli-Lopez, A.; Wen, J.; Buren, S.; Mysore, K. S.; Bokhari, S. N. H.; Imperial, J.; Escudero, V.; Gonzalez-Guerrero, M.
10.1101/2023.03.05.531139 — plant biology — Posted on 2023-03-05
4014 ATP1A1-linked diseases require a malfunctioning protein product from one allele
Spontarelli, K.; Young, V. C.; Sweazey, R.; Padro, A.; Lee, J.; Bueso, T.; Hernandez, R. M.; Kim, J.; Katz, A.; Rossignol, F.; Turner, C.; Wilczewski, C. M.; Maxwell, G.; Holmgren, M.; Bailoo, J. D.; Yano, S. T.; Artigas, P.
10.1101/2023.03.05.531165 — physiology — Posted on 2023-03-05
4015 Regional Heterogeneity of Aortic Histology and Transcriptomes in Young Cynomolgus Monkeys
Amioka, N.; Ito, S.; Franklin, M.; Liang, C.-L.; Katsumata, Y.; Cai, L.; Temel, R. E.; Daugherty, A.; Lu, H. S.; Sawada, H.
10.1101/2023.03.04.530901 — pathology — Posted on 2023-03-05
4019 A unique symbiosome in an anaerobic single-celled eukaryote
Jerlström-Hultqvist, J.; Gallot-Lavallee, L.; Salas-Leiva, D. E.; Curtis, B. A.; Zahonova, K.; Cepicka, I.; Stairs, C. W.; Pipaliya, S.; Dacks, J. B.; Archibald, J. M.; Roger, A. J.
10.1101/2023.03.03.530753 — evolutionary biology — Posted on 2023-03-05
4020 Movements and habitat selection of a marsupial carnivore in a modified landscape
Jones, E. M.; Koch, A. J.; Pay, J. M.; Mann, D. F.; Jones, M. E.; Hamede, R. K.
10.1101/2023.03.05.531208 — ecology — Posted on 2023-03-05
4021 In vivo reprogramming of wound-resident cells generates skin with hair
Moriwaki, Y.; Shen, Q.; Okada, H.; Du, Z.; Suga, S.; Kato, M.; Numahata, T.; Li, K.; Kanayama, K.; Okazaki, M.; Izpisua Belmonte, J. C.; Hojo, H.; Kurita, M.
10.1101/2023.03.05.531138 — cell biology — Posted on 2023-03-05
4022 Identification and characterization of structural and regulatory cell-shape determinants in Haloferax volcanii
Schiller, H.; Kouassi, J.; Hong, Y.; Rados, T.; Kwak, J.; DiLucido, A.; Safer, D.; Marchfelder, A.; Pfeiffer, F.; Bisson-Filho, A.; Schulze, S.; Pohlschroder, M.
10.1101/2023.03.05.531186 — microbiology — Posted on 2023-03-05
4023 Vaccine induction of CD4-mimicking broadly neutralizing antibody precursors in macaques
Saunders, K.; Counts, J.; Stalls, V.; Edwards, R.; Manne, K.; Lu, X.; Thakur, B.; Mansouri, K.; Chen, Y.; Parks, R.; Barr, M.; Sutherland, L.; Bal, J.; Havill, N.; Chen, H.; Machiele, E.; Jamieson, N.; Hora, B.; Kopp, M.; Janowska, K.; Anasti, K.; Jiang, C.; Venkatayogi, S.; Eaton, A.; Henderson, R.; Barbosa, C.; Alam, S. M.; Santra, S.; Weissman, D.; Moody, M. A.; Cain, D. W.; Tam, Y.; Lewis, M.; Williams, W. B.; Wiehe, K.; Montefiori, D.; Acharya, P.; Haynes, B. F.
10.1101/2023.03.05.531154 — immunology — Posted on 2023-03-05
4025 Development and applications of chimera platforms for tyrosine phosphorylation
Pergu, R.; Shoba, V. M.; Chaudhary, S. K.; Godage, D. N. P. M.; Deb, A.; Singha, S.; Dhawa, U.; Anokhina, V.; Singh, S.; Siriwardena, S. U.; Choudhary, A.
10.1101/2023.03.05.531183 — biochemistry — Posted on 2023-03-05
4028 Discovery and characterization of non-canonical E2 conjugating enzymes
Abdul Rehman, S. A.; Di Nisio, E.; Cazzaniga, C.; Antico, O.; Knebel, A.; Johnson, C.; Lamoliatte, F.; Negri, R.; Muqit, M.; De Cesare, V.
10.1101/2023.03.05.531151 — biochemistry — Posted on 2023-03-05
4029 Using double cut in vitro assembled CRISPR/Cas9 to modify the genome of Coccidioides posadasii
Mead, H.; Teixeira, M. M.; Blackmon, A.; Kollath, D. R.; Barker, B. M.; Morales, M. M.; Bryant, M.; Itogawa, A.
10.1101/2023.03.04.531116 — molecular biology — Posted on 2023-03-05
4031 FBP1 is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
Gu, L.; Zhu, Y.; Watari, K.; Lee, M.; Liu, J.; Perez, S.; Thai, M.; Mayfield, J.; Zhang, B.; Rocha, K. C. e.; Li, F.; Kim, L.; Jones, A. C.; Wierzbicki, I. H.; Liu, X.; Newton, A. C.; Kisseleva, T.; Lee, J. H.; Ying, W.; Gonzalez, D. J.; Saltiel, A.; Simon, M. C.; Karin, M.
10.1101/2023.03.05.531181 — molecular biology — Posted on 2023-03-05
4032 Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast differentiation
PADILLA-BENAVIDES, T.; Olea-Flores, M.; Sharma, T.; Syed, S. A.; Witwicka, H.; Zuniga-Eulogio, M. D.; Zhang, K.; Navarro-Tito, N.; Imbalzano, A. N.
10.1101/2023.03.05.531193 — molecular biology — Posted on 2023-03-05
4033 IntS6 and the Integrator phosphatase module tune the efficiency of select premature transcription termination events
Fujiwara, R.; Zhai, S.-N.; Liang, D.; Tracey, M.; Ma, X.-K.; Shah, A. P.; Fields, C. J.; Mendoza-Figueroa, M. S.; Meline, M. C.; Tatomer, D. C.; Yang, L.; Wilusz, J. E.
10.1101/2023.03.05.531184 — molecular biology — Posted on 2023-03-05
4035 Closely related Bacteroides of the murine intestinal microbiota affect each other's growth positively or negatively
Fokt, H.; Sakalyte, G.; Unni, R.; Abukhalaf, M.; Cassidy, L.; Marinos, G.; Godfroid, M.; Kinfu, B. M.; Schmitz, R. A.; Kaleta, C.; Tholey, A.; Baines, J. F.; Dagan, T.; Unterweger, D.
10.1101/2023.03.05.530569 — microbiology — Posted on 2023-03-05
4038 An IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich microenvironment in multiple myeloma
de Jong, M. M.; Fokkema, C.; Papazian, N.; van Heusden, T.; Vermeulen, M.; Hoogenboezem, R.; van Beek, G.; Tahri, S.; Sanders, M. A.; van de Woestijne, P.; Gay, F.; Moreau, P.; Büttner-Herold, M.; Bruns, H.; van Duin, M.; Broijl, A.; Sonneveld, P.; Cupedo, T.
10.1101/2023.03.03.530773 — immunology — Posted on 2023-03-05
4039 Transcription factor interactions explain the context-dependent activity of CRX binding sites
Loell, K. J.; Friedman, R. Z.; Myers, C. A.; Corbo, J. C.; Cohen, B. A.; White, M. A.
10.1101/2023.03.05.531194 — systems biology — Posted on 2023-03-05
4041 MerTK mediates the immunologically silent uptake of alpha-synuclein fibrils by human microglia
Dorion, M.-F.; Senkevich, K.; Yaqubi, M.; Kieran, N. W.; Chen, C. X.- Q.; MacDonald, A.; Luo, W.; Wallis, A.; Shlaifer, I.; Hall, J.; Dudley, R. W. R.; Glass, I. A.; Birth Defects Research Laboratory, ; Straton, J. A.; Fon, E. A.; Bartels, T.; Antel, J. P.; Gan-Or, Z.; Durcan, T. M.; Healy, L. M.
10.1101/2023.03.04.531108 — cell biology — Posted on 2023-03-05
4042 Chromatin binding by HORMAD proteins regulates meiotic recombination initiation
Milano, C. R.; Ur, S. N.; Gu, Y.; Tromer, E. C.; Zhang, J.; Hochwagen, A.; Corbett, K. D.
10.1101/2023.03.04.531117 — cell biology — Posted on 2023-03-05
4044 An intracellular hydrophobic nexus is critical for slow deactivation in hERG channels
Stevens-Sostre, W. A.; Flores-Aldama, L.; Bustos, D.; Li, J.; Delemotte, L.; Robertson, G.
10.1101/2023.03.04.531007 — biophysics — Posted on 2023-03-05
4047 Mutant huntingtin expression in the hypothalamus promotes ventral striatal neuropathology
Soylu-Kucharz, R.; Adlesic, N.; Davidsson, M.; Bjorklund, T.; Bjorkqvist, M.; Petersen, A.
10.1101/2023.03.04.530949 — neuroscience — Posted on 2023-03-04
4048 Brain mechanisms of reversible symbolic reference:a potential singularity of the human brain
van Kerkoerle, T.; Pape, L.; Ekramnia, M.; FENG, X.; Tasserie, J.; Dupont, M.; Li, X.; Jarraya, B.; Vanduffel, W.; Dehaene-Lambertz, G.; Dehaene, S.
10.1101/2023.03.04.531109 — neuroscience — Posted on 2023-03-04
4049 Unsupervised decomposition and description of nonhuman primate behavior
Mimura, K.; Matsumoto, J.; Mochihashi, D.; Nakamura, T.; Nishijo, H.; Higuchi, M.; Hirabayashi, T.; Minamimoto, T.
10.1101/2023.03.04.531044 — neuroscience — Posted on 2023-03-04
4050 Brain-wide mapping of neuronal architecture controlling torpor
Yamaguchi, H.; Murphy, K. R.; Fukatsu, N.; Sato, K.; Yamanaka, A.; de Lecea, L.
10.1101/2023.03.03.531064 — neuroscience — Posted on 2023-03-04
4051 Hippocampal subfield CA1-3 shows differential structural and functional network plasticity after stress-reducing socio-affective mental training
Valk, S. L.; Engert, V.; Puhlmann, L.; Linz, R.; Caldairou, B.; Bernasconi, A.; Bernasconi, N.; Bernhardt, B. C.; Singer, T.
10.1101/2023.03.03.531039 — neuroscience — Posted on 2023-03-04
4053 Erasable Hippocampal Neural Signatures Predict Memory Discrimination
Kinsky, N. R.; Orlin, D. J.; Ruesch, E. A.; Diba, K.; Ramirez, S.
10.1101/2023.02.02.526824 — neuroscience — Posted on 2023-03-04
4054 Sodium regulates PLC and IP3R-mediated calcium signalling in invasive breast cancer cells
James, A. D.; Unthank, K. P.; Jones, I.; Sajjaboontawee, N.; Sizer, R. E.; Chawla, S.; Evans, G. J. O.; Brackenbury, W. J.
10.1101/2022.08.10.503447 — cancer biology — Posted on 2023-03-04
4059 RatXcan: Framework for translating genetic results between species via transcriptome-wide association analyses
Santhanam, N.; Sanchez-Roige, S.; Liang, Y.; Chitre, A.; Munro, D.; Chen, D.; Cheng, R.; Nyasimi, F.; Perry, M.; Gao, J.; George, A. M.; Gileta, A.; Holl, K.; Hughson, A.; King, C. P.; Lamparelli, A. C.; Martin, C. D.; Martinez, A. G.; Mi, S.; St. Pierre, C. L.; Tripi, J.; Wang, T.; Chen, H.; Flagel, S.; Ishiwari, K.; Meyer, P.; Saba, L.; Woods, L. S.; Polesskaya, O.; Palmer, A. A.; Im, H. K.
10.1101/2022.06.03.494719 — genomics — Posted on 2023-03-04
4060 Single-cell Genome-and-Transcriptome sequencing without upfront whole-genome amplification reveals cell state plasticity of melanoma subclones
Theunis, K.; Vanuytven, S.; Rambow, F.; Brown, D.; Vanderhaegen, M.; Marin-Bejar, O.; Rogiers, A.; Vanraemdonck, N.; Leucci, E.; Demeulemeester, J.; Sifrim, A.; Marine, J.-C.; Voet, T.
10.1101/2023.01.13.521174 — genomics — Posted on 2023-03-04
4061 Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
Chen, X.; Li, Y.; Xu, J.; Cui, Y.; Wu, Q.; Yin, H.; Li, Y.; Jiang, L.; Wang, H.; Wen, Z.; Yao, Z.; Wu, Z.
10.1101/2022.10.22.513336 — developmental biology — Posted on 2023-03-04
4062 Aging Atlas Reveals Cell-Type-Specific Regulation of Pro-longevity Strategies
Gao, S. M.; Qi, Y.; Zhang, Q.; Mohammed, A. S.; Lee, Y.-T.; Guan, Y.; Li, H.; Fu, Y.; Wang, M. C.
10.1101/2023.02.28.530490 — developmental biology — Posted on 2023-03-04
4064 Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors
Myszczyszyn, A.; Popp, O.; Kunz, S.; Sporbert, A.; Jung, S.; Penning, L. C.; Fendler, A.; Mertins, P.; Birchmeier, W.
10.1101/2023.02.28.530413 — cell biology — Posted on 2023-03-04
4066 Addition of adjuvant to DTaP modulates vaccine-induced immunological responses but is insufficient to improve protection in CD-1 mice
Weaver, K. L.; Pyles, G. M.; Dublin, S. R.; Huckaby, A. B.; Miller, S. J.; Gutierrez, M. d. l. P.; Sen-Kilic, E.; Witt, W. T.; Boehm, D. T.; Damron, F. H.; Barbier, M.
10.1101/2023.03.03.530983 — immunology — Posted on 2023-03-04
4067 Semantic novelty modulates neural responses to visual change across the human brain
Nentwich, M.; Leszczynski, M.; Russ, B. E.; Hirsch, L.; Markowitz, N.; Sapru, K.; Schroeder, C. E.; Mehta, A.; Bickel, S.; Parra, L. C.
10.1101/2022.06.20.496467 — neuroscience — Posted on 2023-03-04
4069 JAMS - A framework for the taxonomic and functional exploration of microbiological genomic data
McCulloch, J. A.; Badger, J. H.; Cannon, N.; Rodrigues, R. R.; Valencia, M.; Barb, J. J.; Fernandes, M. R.; Balaji, A.; Crowson, L.; O'hUigin, C.; Dzutsev, A.; Trinchieri, G.
10.1101/2023.03.03.531026 — bioinformatics — Posted on 2023-03-04
4070 Structural basis of activation and inhibition of the Ca2+/calmodulin-sensitive adenylyl cyclase 8
Khanppnavar, B.; Schuster, D.; Özel, M.; Mehta, V.; Leitner, A.; Picotti, P.; Korkhov, V. M.
10.1101/2023.03.03.531047 — biochemistry — Posted on 2023-03-04
4072 A redox-regulated, heterodimeric NADH:cinnamate reductase in Vibrio ruber
Bertsova, Y. V.; Serebryakova, M.; Anashkin, V. A.; Baykov, A. A.; Bogachev, A. V.
10.1101/2023.03.04.531086 — biochemistry — Posted on 2023-03-04
4075 A nucleosome switch primes Hepatitis B Virus infection
Prescott, N.; Mansisidor, A.; Bram, Y.; Lemmon, A. A.; Lim, C.; Risca, V. I.; Schwartz, R. E.; David, Y.
10.1101/2023.03.03.531011 — molecular biology — Posted on 2023-03-04
4077 Litter Matters: The Importance of Decomposition Products for Soil Bacterial Diversity and abundance of key groups of the N cycle in Tropical Areas
Diniz, P. P.; Borges, B. M. F.; Oliveira, A. P. d.; Coelho, M. R.; Aragao, O. O. d. S.; Ribeiro, T. G.; Rocha, F. I.; Coelho, M. R. R.; Dias, E. S.; Cole, J. R. R.; Howe, A. C.; Mui, T. S.; Jesus, E. d. C.
10.1101/2023.03.03.530969 — microbiology — Posted on 2023-03-04
4081 S100A1ct: a synthetic peptide derived from human S100A1 protein improves cardiac contractile performance and survival in pre-clinical heart failure models
Kehr, D.; Ritterhoff, J.; Glaser, M.; Jarosch, L.; Salazar, R.; Spaich, K.; Varadi, K.; Birkenstock, J.; Egger, M.; Gao, E.; Koch, W. J.; Katus, H. A.; Frey, N.; Jungmann, A.; Busch, C.; Mather, P. J.; Ruhparwar, A.; Voelkers, M.; Wade, R. C.; Most, P.
10.1101/2023.03.04.531024 — pharmacology and toxicology — Posted on 2023-03-04
4082 Cardiac-targeted rAAV5-S100A1 gene therapy protects against adverse remodeling and contractile dysfunction in post-ischemic hearts
Kehr, D.; Salatzki, J.; Krautz, B.; Varadi, K.; Birkenstock, J.; Schlegel, P.; Gao, E.; Koch, W. J.; Riffel, J.; Andre, F.; Peppel, K.; Katus, H. A.; Frey, N.; Busch, M.; Pfannkuche, H.; Ritterhoff, J.; Jungmann, A.; Most, P.
10.1101/2023.03.03.529004 — pathology — Posted on 2023-03-04
4085 Computational Scoring and Experimental Evaluation of Enzymes Generated by Neural Networks
Johnson, S. R.; Fu, X.; Viknander, S.; Goldin, C.; Monaco, S.; Zelezniak, A.; Yang, K. K.
10.1101/2023.03.04.531015 — biochemistry — Posted on 2023-03-04
4086 Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP
Peter, M. F.; Ruland, J. A.; Kim, Y.; Hendricks, P.; Siebrasse, J. P.; Thomas, G. H.; Kubitscheck, U.; Hagelueken, G.
10.1101/2023.03.04.531103 — biochemistry — Posted on 2023-03-04
4087 Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G-protein subunits
Park, J.-C.; Luebbers, A.; Dao, M.; Semeano, A.; Papakonstantinou, M. P.; Broselid, S.; Yano, H.; Martemyanov, K.; Garcia-Marcos, M.
10.1101/2023.03.03.529094 — biochemistry — Posted on 2023-03-04
4088 Early life exposure to cigarette smoke is associated with lung function changes and primes gene expression and DNA methylation changes at Cyp1a1 upon exposure later in life
Onuzulu, C. D.; Lee, S.; Basu, S.; Comte, J.; Hai, Y.; Hizon, N.; Chadha, S.; Fauni, M. S.; Kahnamoui, S.; Xiang, B.; Halayko, A. J.; Dolinsky, V. W.; Pascoe, C. D.; Jones, M. J.
10.1101/2023.03.03.530858 — genetics — Posted on 2023-03-04
4092 PPP1R3B is a metabolic switch that shifts hepatic energy storage from lipid to glycogen
Creasy, K. T.; Mehta, M.; Park, J.; Schneider, C. V.; Shewale, S.; Millar, J. S.; Hand, N. J.; Baur, J. A.; Rader, D. J.
10.1101/2023.03.04.529958 — molecular biology — Posted on 2023-03-04
4094 Mutagenic-end joining results in smaller deletions in heterochromatin relative to euchromatin
Miller, J. M.; Prange, S.; Ji, H.; Rau, A. R.; Butova, N. L.; Lutter, A.; Chung, H.; Merigliano, C.; Rawal, C. C.; McVey, M.; Chiolo, I.
10.1101/2023.03.03.531058 — cell biology — Posted on 2023-03-04
4095 Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3
Kobori, C.; Takagi, R.; Yokomizo, R.; Yoshihara, S.; Mori, M.; Takahashi, H.; Javaregowda, P. K.; Akiyama, T.; Ko, M. S. H.; Kishi, K.; UMEZAWA, A.
10.1101/2023.03.03.530736 — cell biology — Posted on 2023-03-04
4096 Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling
Trinh, V. Q.-H.; Lee, T.-F.; Lemoinne, S.; Ray, K. C.; Ybanez, M. D.; Tsuchida, T.; Carter, J. K.; Agudo, J.; Brown, B. D.; Akat, K. M.; Friedman, S. L.; Lee, Y. A.
10.1101/2023.03.03.531042 — cell biology — Posted on 2023-03-04
4100 CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth
Yang, J.; Bergdorf, K.; Yan, C.; Luo, W.; Chen, S.-C.; Ayers, D.; Liu, Q.; Liu, X.; Boothby, M. R.; Groves, S. M.; Oleskie, A.; Zhang, X.; Maeda, D.; Zebala, J.; Quaranta, V.; Richmond, A.
10.1101/2023.02.22.529548 — cancer biology — Posted on 2023-03-04
4101 Mechanobiology of Fibroblast Activation in Skin Grafting
Hong, Y.; Peng, X.; Yu, H.; Jafari, M.; Shakiba, D.; Huang, Y.; Qu, C.; Melika, E.; Tawadros, A.; Mujahid, A.; Sandler, J.; Pryse, K.; Sacks, J.; Elson, E.; Genin, G.; Alisafaei, F.
10.1101/2022.10.12.511903 — biophysics — Posted on 2023-03-04
4105 Early life exposure to broccoli sprouts confers stronger protection against enterocolitis development in an immunological mouse model of inflammatory bowel disease.
Holcomb, L.; Holman, J. M.; Hurd, M.; Lavoie, B.; Colucci, L.; Hunt, B.; Hunt, T.; Mawe, G. M.; Moses, P. L.; Perry, E.; Stratigakis, A.; Zhang, T.; Chen, G.; Ishaq, S. L.; Li, Y.
10.1101/2023.01.27.525953 — microbiology — Posted on 2023-03-04
4107 Spatial tuning in nociceptive processing is driven by attention
Adamczyk, W. M.; Katra, M.; Szikszay, T.; Peugh, J.; King, C.; Luedtke, K.; Coghill, R. C.
10.1101/2022.06.16.496352 — neuroscience — Posted on 2023-03-04
4111 The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent
Suchacki, K. J.; Thomas, B. J.; Ikushima, Y. M.; Chen, K.-C.; Fyfe, C.; Tavares, A. A. S.; Woodward, H. J.; Sulston, R. J.; Lovdel, A.; Han, X.; Mattiucci, D.; Brain, E. J.; Kobayashi, H.; Gray, G. A.; Whitfield, P. D.; Stimson, R. H.; Alcaide-Corral, C. J.; Morton, N. M.; Johnstone, A. M.; Cawthorn, W. P.
10.1101/2022.02.20.481222 — physiology — Posted on 2023-03-04
4112 Transcription elongation defects link oncogenic splicing factor mutations to targetable alterations in chromatin landscape
Boddu, P. C.; Gupta, A. K.; Roy, R.; De La Pena Avalos, B.; Olazabal Herrero, A.; Neuenkirchen, N.; Zimmer, J. T.; Chandhok, N. S.; King, D.; Nannya, Y.; Ogawa, S.; Lin, H.; Simon, M. D.; Dray, E.; Kupfer, G.; Verma, A. K.; Neugebauer, K. M.; Pillai, M. M.
10.1101/2023.02.25.530019 — cancer biology — Posted on 2023-03-04
4113 ICAT: A Novel Algorithm to Robustly Identify Cell States Following Perturbations in Single Cell Transcriptomes
Hawkins, D. Y.; Zuch, D. T.; Huth, J.; Rodriguez-Sastre, N. C.; McCutcheon, K. R.; Glick, A.; Lion, A. T.; Thomas, C. F.; Descoteaux, A.; Johnson, W. E.; Bradham, C.
10.1101/2022.05.26.493603 — bioinformatics — Posted on 2023-03-04
4116 Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models
Smith, D. M.; Loughnan, R. J.; Friedman, N. P.; Parekh, P.; Frei, O.; Thompson, W. K.; Andreassen, O.; Neale, M.; Jernigan, T. L.; Dale, A.
10.1101/2022.10.28.512918 — genetics — Posted on 2023-03-04
4122 Steamed broccoli sprouts alleviate gut inflammation and retain gut microbiota against DSS-induced symptoms.
Holman, J. M.; Colucci, L.; Baudewyns, D.; Balkan, J.; Hunt, T.; Hunt, B.; Holcomb, L.; Chen, G.; Moses, P. L.; Mawe, G. M.; Zhang, T.; Li, Y.; Ishaq, S. L.
10.1101/2023.01.27.522641 — microbiology — Posted on 2023-03-04
4128 Long-term cellular and molecular signatures of pregnancy in the adult and ageing brain
Duarte Guterman, P.; Richard, J.; Lieblich, S.; Eid, R.; Lamers, Y.; Galea, L. A.
10.1101/2023.02.24.529879 — neuroscience — Posted on 2023-03-04
4129 Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
Menegollo, M.; Bentham, R. B.; Henriques, T.; Ng, S. Q.; Ren, Z.; Esculier, C.; Agarwal, S.; Tong, E.; Ilangovan, S.; Szabadkai, Z.; Suman, M.; Patani, N.; Ghanate, A.; Bryson, K.; Stein, R. C.; Yuneva, M.; Szabadkai, G.
10.1101/2023.02.17.528922 — systems biology — Posted on 2023-03-04
4130 Root cap cell corpse clearance limits microbial colonization
Charura, N. M.; Llamas, E.; De Quattro, C.; Vilchez, D.; Nowack, M. K.; Zuccaro, A.
10.1101/2023.02.03.526420 — plant biology — Posted on 2023-03-04
4137 The pyruvate dehydrogenase complex regulates mitophagic selectivity and matrix protein phosphorylation
Kolitsida, P.; Nolic, V.; Stumpe, M.; Zhou, J.; Niemi, N. M.; Dengjel, J.; Abeliovich, H.
10.1101/2022.03.16.484611 — cell biology — Posted on 2023-03-04
4139 Sensing volatiles throughout the body: Geographic and tissue-specific olfactory receptor expression in the fig wasp Ceratosolen fusciceps
Krishnan, S.; Karpe, S. D.; Hithesh, C. K.; Nongbri, L. B.; Sowdhamini, R.; Grosse-Wilde, E.; Hansson, B.; Borges, R. M.
10.1101/2023.03.03.530950 — genomics — Posted on 2023-03-03
4140 PREMISE: A database of 20 Macaca Fascicularis PET/MRI brain imaging available for research
Chalet, L.; Debatisse, J.; Wateau, O.; Boutelier, T.; Wiart, M.; Costes, N.; Merida, I.; Redoute, J.; Langlois, J.-B.; Lancelot, S.; Leon, C.; Cho, T.-H.; Mechtouff, L.; Eker, O.; Nighoghossian, N.; Canet-Soulas, E.; Becker, G.
10.1101/2023.03.03.530981 — scientific communication and education — Posted on 2023-03-03
4141 A drug repurposing screen for whipworms informed by comparative genomics
Coghlan, A.; Partridge, F. A.; Duque-Correa, M. A.; Rinaldi, G.; Clare, S.; Seymour, L.; Brandt, C.; Mkandawire, T. T.; McCarthy, C.; Holroyd, N.; Nick, M.; Brown, A. E.; Tonitiwong, S.; Sattelle, D. B.; Berriman, M.
10.1101/2023.03.02.530747 — pharmacology and toxicology — Posted on 2023-03-03
4142 Melanotransferrin Functions as a Pro-Oncogenic WNT Agonist: A Yin-Yang Relationship in Melanoma with the WNT Antagonist and Metastasis Suppressor, NDRG1
Richardson, D. R.; Paluncic, J.; Gholam Azad, M.; Lanbe, D.; Skoda, J.; Park, K.; Chiang, S.; Bae, D.-H.; Scolyer, R.; Afroz, R.; Babu, G.; Wilmott, J.; Loh, K.; Jansson, P.; Dharmasivam, M.; Huang, M.; Zhao, X.; Kovacevic, Z.
10.1101/2023.02.27.530353 — cancer biology — Posted on 2023-03-03
4144 Sequence-based prediction of the solubility of peptides containing non-natural amino acids
Oeller, M.; Kang, R.; Bolt, H.; Gomes dos Santos, A.; Langborg Weinmann, A.; Nikitidis, A.; Zlatoidsky, P.; Su, W.; Czechtizky, W.; De Maria, L.; Sormanni, P.; Vendruscolo, M.
10.1101/2023.03.03.530952 — biophysics — Posted on 2023-03-03
4145 Decoding Duchenne muscular dystrophy transcriptome to single nuclei level reveals clinical-genetic correlations
Suarez-Calvet, X.; Fernandez-Simon, E.; Natera, D.; Jou, C.; Pinol-Jurado, P.; Villalobos, E.; Ortez, C.; Monceau, A.; Schiava, M.; Verdu-Diaz, J.; Clark, J.; Laidler, Z.; Mehra, P.; Gokul-Nath, R.; Alonso-Perez, J.; Marini-Bettolo, C.; Tasca, G.; Straub, V.; Guglieri, M.; Nascimento, A.; Diaz-Manera, J.
10.1101/2023.03.01.530728 — bioinformatics — Posted on 2023-03-03
4148 Electron microscopic analysis of the influence of iPSC-derived motor neurons on bioengineered human skeletal muscle tissues
Nguyen, C. T.; Cahvez-Madero, C.; Jacques, E.; Musgrave, B.; Yin, T.; Saraci, K.; Gilbert, P. M.; Stewart, B. A.
10.1101/2023.03.03.530083 — cell biology — Posted on 2023-03-03
4149 Cardiomyocyte transcriptomic signatures in response to Trypanosoma cruzi infection underpin Chagas cardiomyopathy progression.
Candray, K.; Nakagama, Y.; Masamichi, I.; Nakagama, S.; Tshibangu-Kabamba, E.; Takeda, N.; Sugiura, Y.; Nitahara, Y.; Michimuko-Nagahara, Y.; Kaku, N.; Onizuka, Y.; Arias, C.-E.; Mejia, M.; Alas, K.; Pena, S.; Maejima, Y.; Komuro, I.; Nakajima-Shimada, J.; Kido, Y.
10.1101/2023.02.27.530371 — cell biology — Posted on 2023-03-03
4153 Recombinant dimeric PDZ protein inhibitors for long-term relief of chronic pain by AAV therapeutics
Noes-Holt, G.; Jensen, K. L.; Richner, M.; Baro, R. C.; Sivertsen, L.; Jager, S. E.; Fernandez, L. J.; Andersen, R. C.; Lilja, J. H.; Larsen, A. H.; Christiansen, N. R.; Tappe-Theodor, A. E.; Vaegter, C. B.; Kuner, R.; Madsen, K. L.; Soerensen, A. T.
10.1101/2023.03.03.530962 — neuroscience — Posted on 2023-03-03
4154 Brain rhythms control microglial response and cytokine expression via NFkappaB signaling
Prichard, A.; Garza, K. M.; Shridhar, A.; He, C.; Bitfaran, S.; Wang, Y.; Goodson, M. C.; Jaeger, D.; Wood, L. B.; Singer, A. C.
10.1101/2023.03.03.530908 — neuroscience — Posted on 2023-03-03
4156 mPD5, an efficacious PICK1 inhibitor for treating chronic pain
Jensen, K. L.; Christensen, N. R.; Noes-Holt, G.; Kanneworff, I. B.; Sivertsen, L.; Baro, R. C.; Jimenez-Fernandez, L.; Goddard, C. M.; Hopkins, C.; Thomsen, C. D.; Soltan, A. B. I.; del Castillo, M. D.; Jager, S. E.; Tidenmand, F. G.; Arleth, L.; Heegaard, A.-M.; Soerensen, A. T.; Madsen, K. L.
10.1101/2023.03.03.530471 — pharmacology and toxicology — Posted on 2023-03-03
4160 Highly pathogenic avian influenza A (H5N1) in marine mammals and seabirds in Peru
Leguia, M.; Garcia-Glaessner, A.; Munoz-Saavedra, B.; Juarez, D.; Barrera, P.; Calvo-Mac, C.; Jara, J.; Silva, W.; Ploog, K.; Amaro, L.; Colchao-Claux, P.; Uhart, M. M.; Nelson, M. I.; Lescano, J.
10.1101/2023.03.03.531008 — genomics — Posted on 2023-03-03
4161 A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs
Venema, W. J.; Hiddingh, S.; van Loosdregt, J.; Bowes, J.; Balliu, B.; de Boer, J. H.; Ossewaarde-van Norel, J.; Thompson, S. D.; Langefeld, C. D.; van der Veken, L. T.; Sofiadis, K.; Krijger, P. H. L.; de Laat, W.; Kuiper, J. J.
10.1101/2023.03.03.530973 — genomics — Posted on 2023-03-03
4162 The global distribution of paired eddy covariance towers
Stoy, P. C.; Chu, H.; Dahl, E.; Cala, D. S.; Shveytser, V.; Wiesner, S.; Desai, A. R.; Novick, K. A.
10.1101/2023.03.03.530958 — ecology — Posted on 2023-03-03
4165 5-iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFkappaB signaling
Chauhan, C.; Kraemer, A.; Knapp, S.; Windheim, M.; Kotlyarov, A.; Menon, M. B.; Gaestel, M.
10.1101/2023.03.03.530727 — cell biology — Posted on 2023-03-03
4166 Environmentally stressed human nucleus pulposus cells trigger the onset of discogenic low back pain
Jiang, W.; Glaeser, J. D.; Kaneda, G.; Sheyn, J.; Wechsler, J. T.; Stephan, S.; Salehi, K.; Chan, J. L.; Tawackoli, W.; Avalos, P.; Johnson, C.; Castaneda, C.; Kanim, L. E.; Tanasansomboon, T.; Burda, J.; Shelest, O.; Yameen, H.; Perry, T. G.; Kropf, M.; Cuellar, J. M.; Seliktar, D.; Bae, H. W.; Stone, L. S.; Sheyn, D.
10.1101/2023.03.02.530506 — molecular biology — Posted on 2023-03-03
4168 Extracellular vesicles of Euryarchaeida: precursor to eukaryotic membrane trafficking
Mills, J.; Gebhard, L. J.; Schubotz, F.; Shevchenko, A.; Speth, D. R.; Liao, Y.; Duggin, I. G.; Marchfelder, A.; Erdmann, S.
10.1101/2023.03.03.530948 — microbiology — Posted on 2023-03-03
4169 Frequent emergence of resistance mutations following complex intra-host genomic dynamics in SARS-CoV-2 patients receiving Sotrovimab
Cabrera, R. P.; Tejerina, F.; Salinas, A. M.; Ferris, M.; Veintimilla, C.; Catalan, P.; Macias, G. R.; Alonso, R.; Munoz, P.; Garcia de Viedma, D.; Perez-Lago, L.
10.1101/2023.03.01.530733 — microbiology — Posted on 2023-03-03
4170 SifA SUMOylation governs Salmonella intracellular survival via modulation of lysosomal function
Srikanth, C. V.; Chandrasekhar, H.; Mohapatra, G.; Singh, M.; Rana, S.; Kaur, N.; Sharma, S.; Tuli, A.; Das, P.
10.1101/2023.03.02.530793 — microbiology — Posted on 2023-03-03
4172 Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
Upadhyay, A.; Chhangani, D.; Rao, N. R.; Kofler, J.; Vassar, R.; Rincon-Limas, D. E.; Savas, J. N.
10.1101/2023.03.03.530975 — neuroscience — Posted on 2023-03-03
4175 Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance
Masson, S. W.; Madsen, S.; Cooke, K. C.; Potter, M.; Vegas, A. D.; Carroll, L.; Thillainadesan, S.; Walder, K. R.; Cooney, G. J.; Morahan, G.; Stöckli, J.; James, D. E.
10.1101/2023.03.01.530673 — systems biology — Posted on 2023-03-03
4179 Structure-based discovery of cannabinoid-1 receptor agonists with reduced side effects
Tummino, T. A.; Iliopoulos-Tsoutsouvas, C.; Braz, J. M.; O'Brien, E. S.; Stein, R. M.; Craik, V.; Tran, N. K.; Ganapathy, S.; Shiimura, Y.; Tong, F.; Ho, T. C.; Radchenko, D. S.; Moroz, Y. S.; Liu, F.; Rosado, S. R.; Bhardwaj, K.; Benitez, J.; Liu, Y.; Kandasamy, H.; Normand, C.; Semache, M.; Sabbagh, L.; Glenn, I.; Irwin, J. J.; Kumar, K. K.; Makriyannis, A.; Basbaum, A. I.; Shoichet, B. K.
10.1101/2023.02.27.530254 — pharmacology and toxicology — Posted on 2023-03-03
4180 Proteomic-based stratification of intermediate-risk prostate cancer patients
Zhong, Q.; Rui, S.; Aref, A. T.; Noor, Z.; Anees, A.; Zhu, Y.; Lucas, N.; Poulos, R. C.; Lyu, M.; Zhu, T.; Wang, B.; Chen, G.-B.; Wang, Y.; Ding, X.; Rutishauser, D.; Rupp, N. J.; Rueschoff, J. H.; Poyet, C.; Hermanns, T.; Fankhauser, C.; Martinez, M. R.; Shao, W.; Buljan, M.; Neumann, J. F.; Beyer, A.; Hains, P. G.; Reddel, R. R.; Robinson, P. J.; Aebersold, R.; Guo, T.; Wild, P. J.
10.1101/2023.03.03.530910 — cancer biology — Posted on 2023-03-03
4181 A large-scale retrospective study in metastatic breast cancer patients using circulating tumor DNA and machine learning to predict treatment outcome and progression-free survival
Beddowes, E. J.; Ortega-Duran, M.; Karapanagiotis, S.; Martin, A.; Gao, M.; Masina, R.; Woitek, R.; Tanner, J.; Tippin, F.; Kane, J.; Lay, J.; Brouwer, A.; Sammut, S.-J.; Chin, S.-F.; Gale, D.; Tsui, D.; Dawson, S. J.; Rosenfeld, N.; Callari, M.; Rueda, O. M.; Caldas, C.
10.1101/2023.03.03.530936 — genomics — Posted on 2023-03-03
4184 Hematophagous triatomine bugs feed also on plants and express functional amylase
Da Lage, J.-L.; Fontenelle, A.; Filee, J.; Merle, M.; Beranger, J.-M.; Almeida, C. E.; Folly Ramis, E.; Harry, M.
10.1101/2023.03.03.530934 — ecology — Posted on 2023-03-03
4186 The infectivity of SARS-CoV-2 progeny virions requires the activity of host cell N-myristoyltransferases and it is severely compromised by their inhibition
Saber, S. H.; Ojha, R.; Quirin, T.; Strandin, T.; Yak, N.; Kant, R.; Kareinen, L.; Sironen, T.; Vapalahti, O.; Balistreri, G.; Joensuu, M.
10.1101/2023.03.03.530798 — microbiology — Posted on 2023-03-03
4187 Inferring gene regulatory networks using transcriptional profiles as dynamical attractors
Li, R.; Rozum, J. C.; Quail, M. M.; Qasim, M. N.; Sindi, S. S.; Nobile, C. J.; Albert, R.; Hernday, A.
10.1101/2023.03.03.530929 — systems biology — Posted on 2023-03-03
4192 Genomic repeat landscape evolution across the teleost fish lineages
Reinar, W. B.; Torresen, O. K.; Nederbragt, A. J.; Matschiner, M.; Jentoft, S.; Jakobsen, K. S.
10.1101/2023.03.03.530935 — evolutionary biology — Posted on 2023-03-03
4197 Species-specific traits mediate avian demographic responses under past climate change
Germain, R. R.; Feng, S.; Chen, G.; Graves, G.; Tobias, J.; Rahbek, C.; Lei, F.; Fjeldsa, J.; Hosner, P.; Gilbert, M. T. P.; Zhang, G.; Nogues-Bravo, D.
10.1101/2022.08.16.504093 — evolutionary biology — Posted on 2023-03-03
4198 Time-independent sensory representations are essential for behavioral learning and perception
Bagur, S.; Bourg, J.; Kempf, A.; Tarpin, T.; Bergaoui, K.; Guo, Y.; Ceballo, S.; Schwenkgrub, J.; Puel, J.-L.; Bourien, J.; Bathellier, B.
10.1101/2022.12.14.520391 — neuroscience — Posted on 2023-03-03
4207 Global epistasis and the emergence of ecological function
Diaz-Colunga, J.; Skwara, A.; Vila, J. C. C.; Bajic, D.; Sanchez, A.
10.1101/2022.06.21.496987 — ecology — Posted on 2023-03-03
4208 Enrichment and delivery of target proteins into the cell cytosol via Outer Membrane Vesicles
Wang, H.; Tao, Z.; Zhao, X.; Wang, G.; Chen, Y.; Zhang, J.; Zhang, X.; Liu, M.; Jiang, G.; He, L.
10.1101/2023.03.02.530906 — cell biology — Posted on 2023-03-03
4209 Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation
Huang, K.; Ashraf, M.; Rohani, L.; Luo, Y.; Sacayanan, A.; Huang, H.; Haegert, A.; Volik, S.; Sar, F.; LeBihan, S.; Liew, J.; Roberts, J. D.; Tibbits, G. F.; Churko, J. M.; Sanatani, S.; Collins, C.; Brunham, L. R.; Laksman, Z. W.
10.1101/2023.03.02.530843 — cell biology — Posted on 2023-03-03
4210 Defective Slc7a7 transport reduces erythropoietin compromising erythropoiesis and iron homeostasis
Giroud-Gerbetant, J.; Sotillo, F.; Hernandez Viedma, G.; Lynch, C.; Ruano, I.; Siri, B.; Sebastian, D.; Zorzano, A.; Artuch, R.; Ormazabal, A.; Sanchez, M.; Weiss, G.; Prats, N.; Dionisi-Vici, C.; Serrano, M.; Palacin, M.; Bodoy, S.
10.1101/2021.08.15.456393 — molecular biology — Posted on 2023-03-03
4212 No isolate, no problem: Using a novel insertion sequence PCR to link rats to human shigellosis cases in an underserved urban community
Ritchie, G.; Leung, V.; Himsworth, C. G.; Byers, K. A.; Lee, L. K.; Chorlton, S. D.; Stefanovic, A.; Romney, M. G.; Matic, N.; Lowe, C. F.
10.1101/2023.03.02.530678 — microbiology — Posted on 2023-03-03
4215 The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide
Rice, M. C.; Kim, J. S.; Imun, M.; Jung, S. W.; Park, C. Y.; Lai, R. W.; Barr, C. R.; Son, J. M.; Tor, K.; Kim, E.; Lu, R. J.; Cohen, I.; Benayoun, B. A.; Lee, C.
10.1101/2023.03.02.530691 — immunology — Posted on 2023-03-03
4218 Development of a versatile LCM-Seq method for spatial transcriptomics of fluorescently-tagged cholinergic neuron populations
Rumpler, E.; Gocz, B.; Skrapits, K.; Sarvari, M.; Takacs, S.; Farkas, I.; Poliska, S.; Papp, M.; Solymosi, N.; Hrabovszky, E.
10.1101/2023.03.02.530916 — neuroscience — Posted on 2023-03-03
4220 Biliatresone treatment of pregnant mice causes changes in bile metabolism and liver inflammation in their offspring
Gupta, K.; Xu, J. P.; Diamond, T.; de Jong, I.; Glass, A. D.; Llewellyn, J.; Theise, N. D.; Winkler, J. D.; Behrens, E. M.; Mesaros, C.; Wells, R. G.
10.1101/2023.03.02.530913 — pharmacology and toxicology — Posted on 2023-03-03
4225 Human Vascularized Bile Duct-on-a Chip: A multi-cellular micro-physiological system for studying Primary Sclerosing Cholangitis
Du, Y.; Gupta, K.; Waisbourd-Zinman, O.; Har-Zahav, A.; Soroka, C. J.; Boyer, J. L.; Llewellyn, J.; Liu, C.; Naji, A.; Polacheck, W. J.; Wells, R. G.
10.1101/2023.03.02.530888 — bioengineering — Posted on 2023-03-03
4227 Combined analysis of transposable elements and structural variation in maize genomes reveals genome contraction outpaces expansion
Munasinghe, M.; Read, A.; Stitzer, M. C.; Song, B.; Menard, C.; Ma, K. Y.; Brandvain, Y.; Hirsch, C. N.; Springer, N.
10.1101/2023.03.02.530873 — genomics — Posted on 2023-03-03
4228 Single-cell RNA-sequencing of bronchoscopy specimens: development of a rapid, minimal-handling protocol
V.Gerayeli, F.; Milne, S.; Yang, C. X.; Li, X.; Guinto, E.; Yang, J. S.-W.; Cheung, C. Y.; Stach, T. R.; Shaipanich, T.; Leung, J. M.; Sin, D. D.
10.1101/2023.03.02.530288 — genomics — Posted on 2023-03-03
4229 Triploid Pacific oysters exhibit stress response dysregulation and elevated mortality following marine heatwaves
George, M. N.; Cattau, O.; Middleton, M.; Lawson, D.; Vadopalas, B.; Gavery, M.; Roberts, S. B.
10.1101/2023.03.02.530828 — genomics — Posted on 2023-03-03
4230 Widespread CRISPR repeat-like RNA regulatory elements in CRISPR-Cas systems
Shmakov, S. A.; Barth, Z.; Makarova, K. S.; Wolf, Y. I.; Brover, V.; Peters, J. E.; Koonin, E. V.
10.1101/2023.03.03.530964 — genomics — Posted on 2023-03-03
4234 Neutrophilic Inflammation in Models of Bronchopulmonary Dysplasia and Chronic Obstructive Pulmonary Disease is Rescued by a Lactobacilli Based Live Biotherapeutic
Nicola, T.; Wenger, N.; Xu, X.; Evans, M.; Rezonzew, G.; Qiao, L.; Yang, Y.; Ambalavanan, N.; Blalock, J. E.; Gaggar, A.; Lal, C. V.
10.1101/2023.03.02.529882 — microbiology — Posted on 2023-03-03
4236 A subset of CD4+ effector memory T cells limit immunity to pulmonary viral infection and prevent tissue pathology via activation of latent TGFβ
McEntee, C. P.; Houston, S.; Finlay, C. M.; Rossi, S.; Liu, G.; Shaw, T. N.; Casulli, J.; Fife, M.; Smedley, C.; Griffith, T. S.; Pepper, M.; Hussell, T.; Hansbro, P. M.; Schwartz, J.-M.; Paidassi, H.; Travis, M. A.
10.1101/2023.03.02.527395 — immunology — Posted on 2023-03-03
4238 Multivariate prediction of cognitive performance from the sleep electroencephalogram
Ujma, P. P.; Bodizs, R.; Dresler, M.; Simor, P.; Purcell, S.; Stone, K.; Yaffe, K.; Redline, S.
10.1101/2023.02.28.530401 — neuroscience — Posted on 2023-03-03
4239 Multimodal neural correlates of childhood psychopathology
Kebets, V.; Piguet, C.; Chen, J.; Ooi, L. Q. R.; Kirschner, M.; Siffredi, V.; Misic, B.; Yeo, B. T. T.; Bernhardt, B.
10.1101/2023.03.02.530821 — neuroscience — Posted on 2023-03-03
4244 Wireless Electrical-Molecular Quantum Signalling for Cancer Cell Induced Death
Jain, A.; Gosling, J.; Liu, S.; Wang, H.; Stone, E.; Perez Garcia, L.; Amabilino, D. B.; Fromhold, T. M.; Smith, S.; Rahman, R.; Long, Y.; Turyanska, L.; Rawson, F.
10.1101/2023.03.02.529075 — biophysics — Posted on 2023-03-03
4245 Identifying the environmental drivers of corridors and predicting connectivity between seasonal ranges in multiple populations of Alpine ibex (Capra ibex) as tools for conserving migration
Chauveau, V.; Garel, M.; Toïgo, C.; Anderwald, P.; Beurier, M.; Bunz, Y.; Bouche, M.; Cagnacci, F.; Canut, M.; Cavailhes, J.; Champly, I.; Filli, F.; Frey-Roos, A.; Gressmann, G.; Herfindal, I.; Jurgeit, F.; Martinelli, L.; Papet, R.; Petit, E.; Ramanzin, M.; Semenzato, P.; Vannard, E.; Loison, A.; Coulon, A.; Marchand, P.
10.1101/2023.03.02.530594 — ecology — Posted on 2023-03-03
4247 Ecological differences among hydrothermal vent symbioses may drive contrasting patterns of symbiont population differentiation
Breusing, C.; Xiao, Y.; Russell, S.; Corbett-Detig, R.; Li, S.; Sun, J.; Chen, C.; Lan, Y.; Qian, P.-Y.; Beinart, R. A.
10.1101/2022.08.30.505939 — evolutionary biology — Posted on 2023-03-03
4251 Small Molecule in situ Resin Capture - an Organism Independent Strategy for Natural Product Discovery.
Bogdanov, A.; Salib, M. N.; Chase, A. B.; Hammerlindl, H.; Muskat, M. N.; Luedtke, S.; O'Donoghue, A. J.; Wu, L. F.; Altschuler, S. J.; Molinski, T. F.; Jensen, P. R.
10.1101/2023.03.02.530684 — biochemistry — Posted on 2023-03-03
4254 CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites.
Lee, H. J.; Moreira, M. d. L.; Li, S.; Williams, C. G.; Skinner, O. P.; Asad, S.; Asatsuma, T.; Bramhall, M. L.; Jiang, Z.; Engel, J. A.; Soon, M. S. F.; Straube, J.; Barrera, I.; Murray, E.; Chen, F.; Nideffer, J. F.; Jagannathan, P.; Haque, A.
10.1101/2023.03.02.530907 — immunology — Posted on 2023-03-03
4256 Expanding the molecular language of protein liquid-liquid phase separation
Rekhi, S.; Garcia, C. G.; Barai, M.; Rizuan, A.; Schuster, B. S.; Kiick, K. L.; Mittal, J.
10.1101/2023.03.02.530853 — biophysics — Posted on 2023-03-03
4257 Capacitance measurements for assessing DNA origami nanostructures
Walawalkar, V.; Sajal, M. S. R.; Gilpin, Y.; Dandin, M. P.; Taylor, R. E.
10.1101/2023.03.02.530881 — bioengineering — Posted on 2023-03-03
4258 Evidence of thermal adaptation in a widely distributed mosquito species
Couper, L. I.; Farner, J. E.; Lyberger, K. P.; Lee, A. S.; Mordecai, E. A.
10.1101/2023.03.02.530886 — ecology — Posted on 2023-03-03
4260 A truncated HIV Tat demonstrates potent and specific latency reversal activity
Van Gulck, E.; Pardons, M.; Nijs, E.; Verheyen, N.; Dockx, K.; Van Den Eynde, C.; Battivelli, E.; Vega, J.; Florence, E.; Autran, B.; Archin, N.; Margolis, D. M.; Katlama, C.; Hamimi, C.; Van Den Wyngaert, I.; Eyassu, F.; Vandekerckhove, L.; Boden, D.
10.1101/2023.03.02.530914 — cell biology — Posted on 2023-03-03
4263 Robust online multiband drift estimation in electrophysiology data
Windolf, C.; Paulk, A. C.; Kfir, Y.; Trautmann, E.; Garcia, S.; Meszena, D.; Munoz, W.; Caprara, I.; Jamali, M.; Boussard, J. C.; Williams, Z. M.; Cash, S. S.; Paninski, L.; Varol, E.
10.1101/2022.12.04.519043 — neuroscience — Posted on 2023-03-03
4264 Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress
Mikati, M. O.; Erdmann-Gilmore, P.; Connors, R.; Conway, S. M.; Malone, J.; Woods, J.; Sprung, R. W.; Townsend, R. R.; Al-Hasani, R.
10.1101/2023.02.15.528745 — neuroscience — Posted on 2023-03-03
4265 Mass Mortality of Marine Mammals Associated to Highly Pathogenic Influenza Virus (H5N1) in South America
Gamarra-Toledo, V.; Plaza, P.; Gutierrez, R.; Inga, G.; Saravia-Guevara, P.; Pereyra-Meza, O.; Coronado-Flores, E.; Calderon-Cerron, A.; Quiroz-Jimenez, G.; Martinez, P.; Huaman-Mendoza, D.; Nieto-Navarrete, J.; Ventura, S.; Lambertucci, S. A.
10.1101/2023.02.08.527769 — pathology — Posted on 2023-03-03
4267 SeqScreen-Nano: a computational platform for rapid, in-field characterization of previously unseen pathogens.
Balaji, A.; Liu, Y.; Nute, M. G.; Hu, B.; Kappell, A.; LeSassier, D.; Godbold, G. D.; Ternus, K. L.; Treangen, T. J.
10.1101/2023.02.10.528096 — bioinformatics — Posted on 2023-03-03
4269 User-friendly analysis of droplet array images
Sanka, I.; Bartkova, S.; Pata, P.; Ernits, M.; Meinberg, M.; Agu, N.; Aruoja, V.; Smolander, O.-P.; Scheler, O.
10.1101/2021.12.21.473684 — bioinformatics — Posted on 2023-03-03
4273 Indel driven rapid evolution of core nuclear pore protein gene promoters
McQuarrie, D. W. J.; Read, A. M.; Stephens, F. H. S.; Civetta, A.; Soller, M.
10.1101/2023.01.04.522740 — evolutionary biology — Posted on 2023-03-03
4275 Aging Atlas Reveals Cell-Type-Specific Regulation of Pro-longevity Strategies
Gao, S. M.; Qi, Y.; Zhang, Q.; Mohammed, A. S.; Lee, Y.-T.; Guan, Y.; Li, H.; Fu, Y.; Wang, M. C.
10.1101/2023.02.28.530490 — developmental biology — Posted on 2023-03-02
4276 Lung mesenchymal cell diversity rapidly increases at birth and is profoundly altered by hyperoxia
Zanini, F.; Che, X.; Suresh, N.; Knutsen, C.; Klavina, P.; Xie, Y.; Domingo-Gonzales, R.; Liu, M.; Jones, R. C.; Quake, S. R.; Alvira, C. M.; Cornfield, D. N.
10.1101/2021.05.19.444776 — cell biology — Posted on 2023-03-02
4278 Two common and distinct forms of variation in human functional brain networks
Dworetsky, A.; Seitzman, B. A.; Adeyemo, B.; Nielsen, A. N.; Hatoum, A. S.; Smith, D. M.; Nichols, T. E.; Neta, M.; Petersen, S. E.; Gratton, C.
10.1101/2021.09.17.460799 — neuroscience — Posted on 2023-03-02
4279 Hierarchical and fine-scale mechanisms of binocular rivalry for conscious perception
Qian, C.; Chen, Z.; Hollander, G. d.; Knapen, T.; Zhang, Z.; He, S.; Zhang, P.
10.1101/2023.02.11.528110 — neuroscience — Posted on 2023-03-02
4280 Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome
Ketchesin, K. D.; Becker-Krail, D. D.; Xue, X.; Wilson, R.; Lam, T. T.; Williams, K.; Nairn, A.; Tseng, G.; Logan, R. W.
10.1101/2023.03.01.530696 — neuroscience — Posted on 2023-03-02
4281 Prefrontal Cortex Encodes Value Pop-out in Visual Search
Abbaszadeh, M.; Panjehpour, A.; Alemohammad, S. M. A.; Ghavampour, A.; Ghazizadeh, A.
10.1101/2023.01.27.525832 — neuroscience — Posted on 2023-03-02
4283 Optimization of host cell-compatible, antimicrobial peptides effective against biofilms and clinical isolates of drug-resistant bacteria.
Ghimire, J.; Hart, R. J.; Soldano, A.; Chen, C.; Guha, S.; Hoffmann, J. P.; Hall, K.; Sun, L.; Nelson, B. J.; Lu, T. K.; Kolls, J. K.; Rivera, M.; Morici, L. A.; Wimley, W. C.
10.1101/2022.12.01.518642 — biochemistry — Posted on 2023-03-02
4284 Emergence of rhythmic chunking in complex stepping of mice
Hirokane, K.; Nakamura, T.; Kubota, Y.; Hu, D.; yagi, t.; Graybiel, A. M.; Kitsukawa, T.
10.1101/2023.03.02.530893 — animal behavior and cognition — Posted on 2023-03-02
4285 Widespread sex ratio polymorphism in Caenorhabditis nematodes
Huang, Y.; Lo, Y.-H.; Hsu, J.-C.; Le, T. S.; Yang, F.-J.; Chang, T.; Braendle, C.; Wang, J.
10.1101/2021.10.26.465869 — evolutionary biology — Posted on 2023-03-02
4286 Prey size spectra and predator to prey size ratios of southern ocean salps
Fender, C. K.; Decima, M.; Gutierrez-Rodriguez, A.; Selph, K. E.; Yingling, N.; Stukel, M. R.
10.1101/2022.02.16.480784 — ecology — Posted on 2023-03-02
4287 A non-invasive, fast on/off 'Odourgenetic' Method to Manipulate Physiology
Wu, Y.; Su, S.; Xu, X.; Hao, X.; Lu, W.; Li, X.; Wang, L.; Tian, W.; Gao, Y.; ke, c.; cao, g.
10.1101/2022.11.25.517891 — cell biology — Posted on 2023-03-02
4288 Dynamical modeling reveals RNA decay mediates the effect of matrix stiffness on aged muscle stem cell fate
Hettinger, Z. R.; Hu, S.; Mamiya, H.; Sahu, A.; Iijima, H.; Wang, K.; Gilmer, G.; Miller, A.; Nasello, G.; D'Amore, A.; Vorp, D. A.; Rando, T. A.; Xing, J.; Ambrosio, F.
10.1101/2023.02.24.529950 — cell biology — Posted on 2023-03-02
4291 A contribution of Death Induced by Survival gene Elimination (DISE) to the neurotoxicity in Alzheimer's disease
Paudel, B.; Jeong, S.-Y.; Martinez, C. P.; Rickman, A.; Haluck-Kangas, A.; Bartom, E. T.; Frederiksen, K.; Affaneh, A.; Kessler, J. A.; Mazzulli, J. R.; Murmann, A. E.; Rogalski, E.; Geula, C.; Ferreira, A.; Heckmann, B. L.; Green, D. R.; Sadleir, K. R.; Vassar, R.; Peter, M. E.
10.1101/2022.09.08.507157 — neuroscience — Posted on 2023-03-02
4294 Persistent DNA methylation changes associated with prenatal NO2 exposure in a Canadian prospective birth study
Lee, S.; Sbihi, H.; MacIsaac, J. L.; Ambalavanan, A.; Mandhane, P. J.; Moraes, T. J.; Turvey, S. E.; Duan, Q.; Subbarao, P.; Brauer, M.; Brook, J. R.; Kobor, M. S.; Jones, M. J.
10.1101/2023.03.02.530668 — genetics — Posted on 2023-03-02
4295 Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4
Saotome, M.; Poduval, D. B.; Grimm, S. A.; Nagornyuk, A.; Gunarathna, S.; Shimbo, T.; Wade, P. A.; Takaku, M.
10.1101/2023.03.02.530867 — genomics — Posted on 2023-03-02
4297 Astrocyte glypican 5 regulates synapse maturation and stabilization
Bosworth, A. P.; Contreras, M.; Novak, S. W.; Sancho, L.; Salas, I. H.; Manor, U.; Allen, N. J.
10.1101/2023.03.02.529949 — neuroscience — Posted on 2023-03-02
4298 Quantitative Nanohistology of aging dermal collagen
Strange, A.; Maeva, A.; Huang, S.; Siddiqui, S.; Bastien, P.; Aguayo, S.; Vaez, M.; Pollock, H.; Ghibaudo, M.; Potter, A.; Pageon, H.; Bozec, L.
10.1101/2023.03.02.530877 — biophysics — Posted on 2023-03-02
4299 Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis
Baer, L.; Barthelson, K.; Postlethwait, J.; Adelson, D. L.; Pederson, S. M.; Lardelli, M.
10.1101/2023.03.02.530865 — genetics — Posted on 2023-03-02
4300 Systematic analyses of the resistance potential of drugs targeting SARS-CoV-2 main protease
Flynn, J. M.; Huang, Q. Y. M.; Zvornicanin, S. N.; Schneider-Nachum, G.; Shaqra, A. M.; Kurt Yilmaz, N.; Moquin, S. A.; Dovala, D.; Schiffer, C. A.; Bolon, D. N. A.
10.1101/2023.03.02.530652 — molecular biology — Posted on 2023-03-02
4302 Detrimental Impact of a Type VI Secretion System on Direct Interspecies Electron Transfer
Smith, J. A.; Holmes, D. E.; Woodard, T. L.; Li, Y.; Liu, X.; Wang, L.-Y.; Meier, D.; Schwarz, I. A.; Lovley, D. R.
10.1101/2023.03.02.530876 — microbiology — Posted on 2023-03-02
4304 Microbiota epigenetically direct tuft cell differentiation to control type 2 immunity
Eshleman, E. M.; Rice, T.; Potter, C.; Waddell, A.; Hashimoto-Hill, S.; Woo, V.; Field, S.; Engleman, L.; Schumacher, M. A.; Frey, M. R.; Denson, L. A.; Finkelman, F. D.; Alenghat, T.
10.1101/2023.03.02.530792 — immunology — Posted on 2023-03-02
4305 A novel hypothalamic-midbrain circuit for model-based learning
Hoang, I. B.; Munier, J. J.; Verghese, A.; Greer, Z.; Millard, S. J.; DiFazio, L. E.; Sercander, C.; Izquierdo, A.; Sharpe, M. J.
10.1101/2023.03.02.530856 — neuroscience — Posted on 2023-03-02
4307 Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression
Hasselluhn, M. C.; Decker-Farrell, A. R.; Vlahos, L.; Thomas, D. H.; Curiel-Garcia, A.; Maurer, H. C.; Wasko, U. N.; Tomassoni, L.; Sastra, S. A.; Palermo, C. F.; Dalton, T. C.; Ma, A.; Li, F.; Tolosa, E. J.; Hibshoosh, H.; Muir, A.; Fernandez-Zapico, M. E.; Califano, A.; Olive, K. P.
10.1101/2023.03.02.529724 — cancer biology — Posted on 2023-03-02
4308 Zbtb46 coordinates angiogenesis and immunity to control tumor outcome
KABIR, A. U.; SUBRAMANIAN, M.; KIM, M.; WU, J.; KRCHMA, K.; WANG, X.; HALABI, C. M.; PAN, H.; WICKLINE, S. A.; FREMONT, D. H.; CHOI, K.
10.1101/2023.03.02.530835 — cancer biology — Posted on 2023-03-02
4310 The unique three-dimensional arrangement of Macrophage Galactose Lectin enables E. coli LipoPolySaccharides recognition through two distinct interfaces
Abbas, M.; Maalej, M.; Nieto Fabregat, F.; Thepaut, M.; Kleman, J.-p.; Ayala, I.; Molinaro, A.; Simorre, J.-P.; Marchetti, R.; Fieschi, F.; Laguri, C.
10.1101/2023.03.02.530591 — biophysics — Posted on 2023-03-02
4312 Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases
Zeng, B.; Bendl, J.; Deng, C.; Lee, D.; Masir, R.; Reach, S. M.; Kleopoulos, S. P.; Auluck, P.; Marenco, S.; Lewis, D. A.; Haroutunian, V.; Ahituv, N.; Fullard, J. F.; Hoffman, G. E.; Roussos, P.
10.1101/2023.03.02.530826 — genomics — Posted on 2023-03-02
4313 Mutational signatures in wild type Escherichia coli strains reveal dominance of DNA polymerase errors
Garushyants, S. K.; Sane, M.; Selifanova, M. V.; Agashe, D. K.; Bazykin, G. A.; Gelfand, M. S.
10.1101/2023.03.02.530848 — evolutionary biology — Posted on 2023-03-02
4315 Iodidimonas, a bacterium unable to degrade hydrocarbons, thrives in a bioreactor treating oil and gas produced water
Acharya, S. M.; Enalls, B. C.; Walian, P. J.; Van Houghton, B. D.; Rosenblum, J. S.; Cath, T. Y.; Tringe, S. G.; Chakraborty, R.
10.1101/2023.03.02.530844 — ecology — Posted on 2023-03-02
4318 The Estrogen Receptor-Related Orphan Receptors (ERRs) Regulate Autophagy through TFEB
Losby, M.; Hayes, M.; Valfort, A.; Walker, J.; Xu, W. L.; Zhang, L.; Billon, C.; Burris, T.
10.1101/2023.03.02.530836 — cell biology — Posted on 2023-03-02
4322 A critical role of a eubiotic microbiota in gating proper immunocompetence in Arabidopsis
Paasch, B. C.; Sohrabi, R.; Kremer, J. M.; Nomura, K.; Martz, J.; Kvitko, B.; Tiedje, J. M.; He, S. Y.
10.1101/2023.03.02.527037 — plant biology — Posted on 2023-03-02
4323 Glycodelin acts as an immunomodulator in NSCLC and is a predictor of poor prognosis for patients receiving immunotherapy
Richtmann, S.; Marwitz, S.; Muley, T.; Koistinnen, H.; Christopoulos, P.; Thomas, M.; Kazdal, D. N.; Allgaeuer, M.; Winter, H.; Goldmann, T.; Meister, M.; Klingmueller, U.; Schneider, M. A.
10.1101/2023.03.02.530822 — cancer biology — Posted on 2023-03-02
4326 Molecular determinants for Rous sarcoma virus intasome assemblies
Bera, S.; Shi, K.; Aihara, H.; Grandgenett, D. P.; Pandey, K. K.
10.1101/2023.03.02.528060 — biochemistry — Posted on 2023-03-02
4330 Seasonal gene-expression signatures of delayed fertilization in Fagaceae
Satake, A.; Ohta, K.; Takeda-Kamiya, N.; Toyooka, K.; Kusumi, J.
10.1101/2023.03.02.530775 — ecology — Posted on 2023-03-02
4333 Isolation of ACE2-dependent and -independent sarbecoviruses from Chinese horseshoe bats
Guo, H.; Li, A.; Dong, T.-Y.; Si, H.-R.; Ben, H.; Li, B.; Zhu, Y.; Shi, Z.; Letko, M. C.
10.1101/2023.03.02.530738 — microbiology — Posted on 2023-03-02
4336 A subset of CD4+ effector memory T cells limit immunity to pulmonary viral infection and prevent tissue pathology via activation of latent TGFβ
McEntee, C. P.; Houston, S.; Finlay, C. M.; Rossi, S.; Liu, G.; Shaw, T. N.; Casulli, J.; Fife, M.; Smedley, C.; Griffith, T. S.; Pepper, M.; Hussell, T.; Hansbro, P. M.; Schwartz, J.-M.; Paidassi, H.; Travis, M. A.
10.1101/2023.03.02.527395 — immunology — Posted on 2023-03-02
4337 Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection
Cooper, L.; Xu, H.; Polmear, J.; Szeto, C.; Pang, E. S.; Gupta, M.; Taylor, J. J.; Jackson, K. J. L.; Nguyen, A.; La Gruta, N.; Martelotto, L. G.; Parish, I. A.; O'Keeffe, M.; Scharer, C. D.; Gras, S.; Good-Jacobson, K. L.
10.1101/2023.03.02.530850 — immunology — Posted on 2023-03-02
4339 Combined statistical-mechanistic modeling links ionchannel genes to physiology of cortical neuron types
Bernaerts, Y.; Deistler, M.; Goncalves, P. J.; Beck, J.; Stimberg, M.; Scala, F.; Tolias, A. S.; Macke, J. H.; Kobak, D.; Berens, P.
10.1101/2023.03.02.530774 — neuroscience — Posted on 2023-03-02
4343 Human white matter myelination rate slows down at birth
Grotheer, M.; Bloom, D.; Kruper, J.; Richie-Halford, A.; Zika, S.; Aguilera Gonzalez, V. A.; Yeatman, J. D.; Grill-Spector, K.; Rokem, A.
10.1101/2023.03.02.530800 — neuroscience — Posted on 2023-03-02
4347 Cell specialization and coordination in Arabidopsis leaves upon pathogenic attack revealed by scRNA-seq.
Delannoy, E.; Batardiere, B.; Pateyron, S.; Soubigou-Taconnat, L.; Chiquet, J.; Colcombet, J.; Lang, J.
10.1101/2023.03.02.530814 — plant biology — Posted on 2023-03-02
4348 Farnesoid X receptor agonism prevents neutrophil extracellular traps via reduced sphingosine-1-phosphate in chronic kidney disease
Jones, B. A.; Myakala, K.; Guha, M.; Davidson, S.; Adapa, S.; Lopez Santiago, I.; Schaffer, I.; Yue, Y.; Allegood, J.; Cowart, L. A.; Wang, X. X.; Rosenberg, A. Z.; Levi, M.
10.1101/2023.03.01.530697 — pharmacology and toxicology — Posted on 2023-03-02
4350 LINC00261 expression reduces mutation accumulation while conferring resistance to cisplatin and altering the tumor-immune microenvironment in lung adenocarcinoma
Castillo, J.; Xue, T.; Joseph, S.; Norwood, M.; Mullen, D. J.; Berrellez, S.; James, S.; Epstein, A. L.; McEachron, T.; Marconett, C. N.
10.1101/2023.03.02.530823 — cancer biology — Posted on 2023-03-02
4355 Shotgun metagenomics unravels higher antibiotic resistome profile in Bangladeshi gut microbiome
Bhattacharjee, A.; Jamal, T. B.; Ahammad, I.; Chowdhury, Z. M.; Rahman, A.; Dewan, G.; Talukder, S.; Hossain, M. U.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.03.02.530749 — genomics — Posted on 2023-03-02
4357 Genetic Inactivation of Beta-Catenin Attenuates and Its Activation Aggravates Desmoplakin Cardiomyopathy
Uzan, M. O.; Fan, S.; Rouhi, L.; Cheedipudi, S.; Cathcart, B.; Jeong, H.-H.; Zhao, Z.; Gurha, P.; Marian, A. J.
10.1101/2023.03.02.530831 — genetics — Posted on 2023-03-02
4358 The eccDNA mediated spread and rapid evolution of herbicide resistance in pigweed interspecific hybrids
Koo, D.-H.; Rajendran, S.; Nakka, S.; Ju, Y.; Nandula, V.; Jugulam, M.; Friebe, B.; Gill, B. S.
10.1101/2023.03.01.530670 — genetics — Posted on 2023-03-02
4360 Identifying the environmental drivers of corridors and predicting connectivity between seasonal ranges in multiple populations of Alpine ibex (Capra ibex) as tools for conserving migration
Chauveau, V.; Garel, M.; Toïgo, C.; Anderwald, P.; Bunz, Y.; Bouche, M.; Cagnacci, F.; Canut, M.; Cavailhes, J.; Champly, I.; Filli, F.; Frey-Roos, A.; Gressmann, G.; Herfindal, I.; Jurgeit, F.; Martinelli, L.; Papet, R.; Petit, E.; Ramanzin, M.; Semenzato, P.; Vannard, E.; Loison, A.; Coulon, A.; Marchand, P.
10.1101/2023.03.02.530594 — ecology — Posted on 2023-03-02
4364 Hypoxic volatile metabolic markers in the MDA-MB-231 breast cancer cell line
Issitt, T.; Reilly, M.; Sweeney, S. T.; Brackenbury, W. J.; Redeker, K.
10.1101/2023.03.02.530779 — cell biology — Posted on 2023-03-02
4365 Translation dynamics in human cells visualized at high-resolution reveal cancer drug action
Xing, H.; Taniguchi, R.; Khusainov, I.; Kreysing, J. P.; Welsch, S.; Turonova, B.; Beck, M.
10.1101/2023.03.02.529652 — cell biology — Posted on 2023-03-02
4366 Physiological stress drives the emergence of a Salmonella subpopulation through ribosomal RNA regulation
Avraham, R.; Ciolli Mattioli, C.; Eisner, K.; Rosenbaum, A.; Wang, M.; Amir, A.; Golding, I.
10.1101/2023.03.02.530801 — microbiology — Posted on 2023-03-02
4370 Spatially-resolved single cell transcriptomics reveal a critical role for γδ T cells in the control of skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection
Alcala, J. F. Q.; Sinton, M. C.; Chandrasegaran, P.; Lestari, A. N.; Heslop, R.; Cheaib, B.; Ogunsola, J.; Ngoyi, D. M.; Swar, N. R. K.; Cooper, A.; Coffelt, S. B.; MacLeod, A.
10.1101/2023.03.01.530674 — immunology — Posted on 2023-03-02
4372 CD8+ cells and small viral reservoirs facilitate post-ART control of SIV in Mauritian cynomolgus macaques
Harwood, O. E.; Matschke, L. M.; Moriarty, R. V.; Balgeman, A. J.; Weaver, A. J.; Ellis-Connell, A. L.; Weiler, A. M.; Winchester, L. C.; Fletcher, C. V.; Friedrich, T.; Keele, B. F.; O'Connor, D. H.; Lang, J. D.; Reynolds, M. R.; O'Connor, S. L.
10.1101/2023.03.01.530655 — immunology — Posted on 2023-03-02
4377 Differential expression of RET and GDNF family receptor, GFR-α1, between striatum and substantia nigra following nigrostriatal lesion: a case for diminished GDNF-signaling
Kasanga, E.; Han, Y.; Navarrete, W.; McManus, R.; Shifflet, M.; Parry, C.; Barahona, A.; Manfredsson, F.; Nejtek, V.; Richardson, J. R.; Salvatore, M. F.
10.1101/2023.03.01.530671 — neuroscience — Posted on 2023-03-02
4380 Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome
Becker-Krail, D.; Ketchesin, K. D. D.; Xue, X.; Wilson, R.; Lam, T. T.; Williams, K.; Nairn, A.; Tseng, G.; Logan, R. W.
10.1101/2023.03.01.530696 — neuroscience — Posted on 2023-03-02
4382 The proton-activated receptor TDAG8 is upregulated in oligodendrocytes during maturation and under acidic conditions.
Opiełka, M.; Caratis, F.; Haussmann, M.; Velasco-Estevez, M.; de Valliere, C.; Seuwen, K.; Rogler, G.; Karaszewski, B.; Rutkowska, A.
10.1101/2023.03.02.530787 — neuroscience — Posted on 2023-03-02
4384 Sleep Deprivation, Sleep Fragmentation and Social Jet Lag increase temperature preference in Drosophila
Roach, T. S.; Ford, M. C.; Simhambhatla, V.; Loutrianakis, V.; Farah, H.; Li, Z.; Periandri, E.; Abdalla, D.; Huang, I.; Kalra, A.; Shaw, P. J.
10.1101/2023.03.02.530812 — neuroscience — Posted on 2023-03-02
4387 The selective estrogen receptor modulator clomiphene inhibits sterol biosynthesis in Arabidopsis thaliana
Wang, Q.; De Vriese, K.; Desmet, S.; Pollier, J.; Lu, Q.; Goossens, A.; Geelen, D.; Russinova, J.; Goeminne, G.; Beeckman, T.; Vanneste, S.
10.1101/2023.03.02.530820 — plant biology — Posted on 2023-03-02
4390 A network medicine approach to elucidate mechanisms underlying menopause-induced knee osteoarthritis
Gilmer, G.; Iijima, H.; Jackson, N.; Hettinger, Z.; Bean, A. C.; Bergmann, J.; Evans, C.; Thurston, R. C.; Ambrosio, F.
10.1101/2023.03.02.530756 — pathology — Posted on 2023-03-02
4391 BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma
Feng, Y.; Cai, L.; Pook, M.; Liu, F.; Chang, C.-H.; Mouti, M. A.; Nibhani, R.; Wu, S.; Deng, S.; Militi, S.; Dunford, J.; Philpott, M.; Fan, Y.; Fan, G.-C.; Liu, Q.; Qi, J.; Sadayappan, S.; Jegga, A. G.; Oppermann, U.; Wang, Y.; Huang, W.; Jiang, L.; Pauklin, S.
10.1101/2023.03.02.530770 — cancer biology — Posted on 2023-03-02
4393 Integrating extracellular vesicle and circulating cell-free DNA analysis on a single plasma aliquot from breast cancer patients improves the detection of HER2 positivity
Mugoni, V.; Ciani, Y.; Quaini, O.; Tomasini, S.; Notarangelo, M.; Vannuccini, F.; Marinelli, A.; Leonardi, E.; Pontalti, S.; Martinelli, A.; Rossetto, D.; Pesce, I.; Mansy, S. S.; Barbareschi, M.; Ferro, A.; Caffo, O.; Attard, G.; Di Vizio, D.; D'Agostino, V. G.; Nardella, C.; Demichelis, F.
10.1101/2023.03.02.530645 — cancer biology — Posted on 2023-03-02
4394 Cholangiocyte primary cilia transduce a fluid shear signal to increase KLF2 via the actin cytoskeleton
Wehrkamp, C. J.; Oleksijew, A. M.; Mansini, A. P.; Gradilone, S. A.; Mohr, A. M.; Mott, J. L.
10.1101/2023.03.01.530694 — cancer biology — Posted on 2023-03-02
4396 Allosteric Communication in the Gating Mechanism for Controlled Protein Degradation by the Bacterial ClpP Peptidase
Dayananda, A.; Dennison, H. T. S.; Fonseka, H. Y. H.; Avestan, M. S.; Wang, Q.; Tehver, R.; Stan, G.
10.1101/2023.03.01.530711 — biophysics — Posted on 2023-03-02
4397 Oligomerization enhances huntingtin membrane activity but is suppressed by covalent crosslinking
Sedighi, F.; Skeens, A.; Adegbuyiro, A.; Bard, J.; Siriwardhana, C.; Donley, E.; Geldenhuys, W. J.; Legleiter, J.
10.1101/2023.03.01.530665 — biophysics — Posted on 2023-03-02
4399 Wireless Electrical-Molecular Quantum Signalling for Cancer Cell Induced Death
Jain, A.; Gosling, J.; Liu, S.; Wang, H.; Stone, E.; Perez Garcia, L.; Amabilino, D. B.; Fromhold, T. M.; Smith, S.; Rahman, R.; Long, Y.; Turyanska, L.; Rawson, F.
10.1101/2023.03.02.529075 — biophysics — Posted on 2023-03-02
4402 Integrating weighted correlation network analysis and machine learning identifies common trajectories of prostate cancer
Egger, G.; Sheibani-Tezerji, R.; Perez Malla, C. U.; Malzer, A.; Misura, K.; Kalla, J.; Tran, L.; Wasinger, G.
10.1101/2023.03.02.530740 — bioinformatics — Posted on 2023-03-02
4403 Fast and accurate DNASeq Variant Calling workflow composed of LUSH toolkit
Wang, T.; Zhang, Y.; Wang, H.; Zheng, Q.; Yang, J.; Zhang, T.; Sun, G.; Liu, W.; Yin, L.; He, X.; You, R.; Wang, C.; Liu, Z.; Liu, Z.; Wang, J.; Jin, X.; He, Z.
10.1101/2023.03.01.530618 — bioinformatics — Posted on 2023-03-02
4404 Small volume blood-brain barrier opening in macaques with a 1 MHz ultrasound phased array
Manuel, T. J.; Sigona, M. K.; Phipps, M. A.; Kusonose, J.; Luo, H.; Yang, P.-F.; Newton, A. T.; Gore, J. C.; Grissom, W.; Chen, L. M.; Caskey, C. F.
10.1101/2023.03.02.530815 — bioengineering — Posted on 2023-03-02
4407 Reentrant condensation of a multicomponent complex system of biomolecules induced by polyphosphate
Furuki, T.; Nobeyama, T.; Suetaka, S.; Matsui, R.; Fukuoka, T.; Arai, M.; Shiraki, K.
10.1101/2023.03.02.530750 — biochemistry — Posted on 2023-03-02
4409 The concordance of length- and sequence-based STRs used in forensic markers with guidance for practice
Sathirapatya, T.; Vongpaisarnsin, K.; Worrapitirungsi, W.; Sukawutthiya, P.; Noh, H.; Pitiwararom, R.
10.1101/2023.03.02.530748 — genetics — Posted on 2023-03-02
4410 Mosaic haplotypes underlie repeated adaptation to whole genome duplication in Arabidopsis lyrata and Arabidopsis arenosa
Bohutinska, M.; Petrikova, E.; Booker, T. R.; Vives Cobo, C.; Vlcek, J.; Sramkova, G.; Postulkova, A.; Hojka, J.; Marhold, K.; Kolar, F.; Yant, L.; Schmickl, R.
10.1101/2023.01.11.523565 — evolutionary biology — Posted on 2023-03-02
4419 Oncomodulin Regulates Spontaneous Calcium Signaling and Maturation of Afferent Innervation in Cochlear Outer Hair Cells
Yang, Y.; Murtha, K. E.; Climer, L. K.; Ceriani, F.; Thompson, P.; Hornak, A. J.; Marcotti, W.; Simmons, D. D.
10.1101/2023.03.01.529895 — developmental biology — Posted on 2023-03-02
4422 OprF impacts Pseudomonas aeruginosa biofilm matrix eDNA levels in a nutrient-dependent manner
Cassin, E.; Araujo-Hernandez, S. A.; Baughn, D. S.; Londono, M. C.; Rodriguez, D. Q.; Tseng, B. S.
10.1101/2023.03.01.530729 — microbiology — Posted on 2023-03-02
4424 Improved spatial knowledge acquisition through sensory augmentation
Schmidt, V.; König, S. U.; Dilawar, R.; Sanchez-Pacheco, T. L.; König, P.
10.1101/2023.02.28.530376 — neuroscience — Posted on 2023-03-02
4428 Time perception reflects individual differences in motor and non-motor symptoms of Parkinson's disease
DiMarco, E.; Sadibolova, R.; Jiang, A.; Liebenow, B. N.; Jones, R. E.; Haq, I. u.; Siddiqui, M. S.; Terhune, D. B.; Kishida, K. T.
10.1101/2023.03.02.530411 — neuroscience — Posted on 2023-03-02
4431 Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population
Regal, J. A.; Guerra Garcia, M. E.; Jain, V.; Chandramohan, V.; Ashley, D. M.; Gregory, S. G.; Thompson, E. M.; Lopez, G. Y.; Reitman, Z. J.
10.1101/2022.12.17.520880 — cancer biology — Posted on 2023-03-02
4433 Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures
Barnett, K. R.; Mobley, R. J.; Diedrich, J. D.; Bergeron, B. P.; Bhattarai, K. R.; Yang, W.; Crews, K. R.; Manring, C. S.; Jabbour, E.; Paietta, E.; Litzow, M. R.; Kornblau, S. M.; Stock, W.; Inaba, H.; Jeha, S.; Pui, C.-H.; Mullighan, C. G.; Relling, M. V.; Yang, J. J.; Evans, W. E.; Savic, D.
10.1101/2023.02.14.528493 — genomics — Posted on 2023-03-02
4435 Exploring neural tracking of acoustic and linguistic speech representations in individuals with post-stroke aphasia
Kries, J.; De Clercq, P.; Gillis, M.; Vanthornhout, J.; Lemmens, R.; Francart, T.; Vandermosten, M.
10.1101/2023.03.01.530707 — neuroscience — Posted on 2023-03-02
4437 Silk Fibroin Particles as Carriers in the Development of All-Natural Hemoglobin-Based Oxygen Carriers (HBOCs)
Pacheco, M. O.; Lutz, H. M.; Armada, J.; Davies, N. A.; Gerzenshtein, I. K.; Cakley, A. S.; Spiess, B. D.; Stoppel, W. L.
10.1101/2023.03.01.530637 — bioengineering — Posted on 2023-03-02
4438 Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
The COVID Moonshot Consortium, ; Achdout, H.; Aimon, A.; Alonzi, D. S.; Arbon, R.; Bar-David, E.; Barr, H.; Ben-Shmuel, A.; Bennett, J.; Bilenko, V. A.; Bilenko, V. A.; Boby, M. L.; Borden, B.; Boulet, P.; Bowman, G. R.; Brun, J.; Brwewitz, L.; BVNBS, S.; Calmiano, M.; Carbery, A.; Carney, D.; Cattermole, E.; Chang, E.; Chernyshenko, E.; Chodera, J. D.; Clyde, A.; Coffland, J. E.; Cohen, G.; Cole, J.; Contini, A.; Cox, L.; Croll, T. I.; Cvitkovic, M.; Dias, A.; Donckers, K.; Dotson, D. L.; Douangamath, A.; Duberstein, S.; Dudgeon, T.; Dunnett, L.; Eastman, P. K.; Erez, N.; Eyermann, C. J.; Fa
10.1101/2020.10.29.339317 — biochemistry — Posted on 2023-03-02
4439 Migration and establishment of progenitor pool of melanocytes is governed by SEMA3E-PLXND1 signaling
Natarajan, V. T.; Subramaniam, Y.; Sharma, B.; Aggarwal, A.; Raja, D. A.; Gupta, I.; Ghazi, M.; Sivasubbu, S.
10.1101/2023.02.28.530560 — developmental biology — Posted on 2023-03-02
4441 A Systems Serology Approach to the Investigation of Infection-Induced Antibody Responses and Protection in Trachoma
Barton, A.; Rosenkrands, I.; Pickering, H.; Faal, N.; Harte, A.; Joof, H.; Makalo, P.; Ragonnet, M.; Weinreich Olsen, A.; Bailey, R. L.; Mabey, D. C.; Follmann, F.; Dietrich, J.; Holland, M. J.
10.1101/2023.03.01.530575 — immunology — Posted on 2023-03-02
4443 Commensal Bacteria Maintain a Qa-1b-restricted Unconventional CD8+ T Population in Gut Epithelium
Guan, J.; Manoharan Valerio, M.; Peske, J. D.; Park, C.; Robey, E. A.; Sadegh-Nasseri, S.; Shastri, N.
10.1101/2023.03.01.530600 — immunology — Posted on 2023-03-02
4445 Active cortical networks promote shunting fast synaptic inhibition in vivo
Burman, R. J.; Brodersen, P. J. N.; Raimondo, J. V.; Sen, A.; Akerman, C. J.
10.1101/2023.03.01.530641 — neuroscience — Posted on 2023-03-02
4446 Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson's GBA-N370S mutation
Do, Q. B.; Ng, B.; Marquez-Gomez, R.; Beccano-Kelly, D.; Ibarra-Aizpurua, N.; Caiazza, M.-C.; Lang, C.; Baleriola, J.; Bengoa-Vergniory, N.; Wade-Martins, R.
10.1101/2023.03.01.530566 — neuroscience — Posted on 2023-03-02
4447 Widespread post-transcriptional regulation of co-transmission
Chen, N.; Zhang, Y.; Rivera-Rodriguez, E.; Yu, A.; Hobin, M.; Rosbash, M.; Griffith, L.
10.1101/2023.03.01.530653 — neuroscience — Posted on 2023-03-02
4448 Investigation of Volatile Metabolites in Sebum as Prodromal Indicators of Parkinson's Disease
Walton-Doyle, C.; Heim, B.; Sinclair, E.; Hollywood, K.; Milne, J.; Holzknecht, E.; Stefani, A.; Hogl, B.; Seppi, K.; Silverdale, M.; Poewe, W.; Barran, P.; Trivedi, D. K.
10.1101/2023.03.01.530578 — neuroscience — Posted on 2023-03-02
4455 Development of a novel epigenetic clock resistant to changes in immune cell composition
Tomusiak, A.; Floro, A.; Tiwari, R.; Riley, R.; Matsui, H.; Andrews, N.; Kasler, H. G.; Verdin, E.
10.1101/2023.03.01.530561 — genomics — Posted on 2023-03-02
4457 Comparative metagenomics reveals host-specific functional adaptation of intestinal microbiota across hominids
Rühlemann, M. C.; Bang, C.; Gogarten, J. F.; Hermes, B. M.; Groussin, M.; Waschina, S. M.; Poyet, M.; Ulrich, M.; Akoua-Koffi, C.; Deschner, T.; Muyembe-Tamfum, J.-J.; Robbins, M. M.; Surbeck, M.; Wittig, R.; Zuberbühler, K.; Baines, J. F.; Leendertz, F. H.; Franke, A.
10.1101/2023.03.01.530589 — evolutionary biology — Posted on 2023-03-02
4458 Reconstruction of the molecular evolution of Usutu virus in Germany: Insights into virus emersion and circulation
Bergmann, F.; Holicki, C. M.; Michel, F.; Bock, S.; Scuda, N.; Priemer, G.; Kenklies, S.; Siempelkamp, T.; Skuballa, J.; Sauerwald, C.; Herms, L.; Muluneh, A.; Peters, M.; Hlinak, A.; Groschup, M. H.; Sadeghi, B.; Ziegler, U.
10.1101/2023.02.28.530558 — evolutionary biology — Posted on 2023-03-02
4459 How Diverse are the Mountain karst Forests of Mexico?
Molina-Paniagua, M. E.; Alves de Melo, P. H.; Barahona, S. R.; Ortiz-Rodriguez, A. E.; Monro, A. K.; Burelo-Ramos, C. M.; Gomez-Dominguez, H.
10.1101/2023.03.01.530643 — ecology — Posted on 2023-03-02
4462 A refined single cell landscape of haematopoiesis in the mouse foetal liver
Ceccacci, E.; Villa, E.; Santoro, F.; Minucci, S.; Ruhrberg, C.; Fantin, A.
10.1101/2023.03.01.530564 — developmental biology — Posted on 2023-03-02
4463 SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns
Fukumura, K.; Sperotto, L.; Seuss, S.; Kang, H.-S.; Yoshimoto, R.; Sattler, M.; Mayeda, A.
10.1101/2022.12.30.522300 — molecular biology — Posted on 2023-03-02
4468 A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain
Tichelman, N. L.; Foerges, A. L.; Elmenhorst, E.-M.; Lange, D.; Hennecke, E.; Baur, D. M.; Beer, S.; Kroll, T.; Neumaier, B.; Bauer, A.; Landolt, H.-P.; Aeschbach, D.; Elmenhorst, D.
10.1101/2023.03.01.530170 — neuroscience — Posted on 2023-03-02
4470 Actomyosin remodeling regulates biomineral formation, growth and morphology during eukaryote skeletogenesis
Hijaze, E.; Gildor, T.; Seidel, R.; Layous, M.; Winter, M.; Bertinetti, L.; Politi, Y.; de-Leon, S. B.-T.
10.1101/2022.12.21.521381 — developmental biology — Posted on 2023-03-02
4471 A Shape Sensing Mechanism driven by Arp2/3 and cPLA2 licenses Dendritic Cells for Migration to Lymph Nodes in Homeostasis
Alraies, Z.; Rivera, C. A.; Delgado, M.-G.; Sanseau, D.; Maurin, M.; Amadio, R.; Maria Piperno, G.; Dunsmore, G.; Yatim, A.; Lacerda Mariano, L.; Saez, P.; Gratia, M.; Lamiable, O.; Moreau, A.; Williart, A.; Albaud, B.; Legoix, P.; Nakano, H.; Cook, D. N.; Lawrence, T.; Manel, N.; Benvenuti, F.; Ginhoux, F.; D. Moreau, H.; Nader, G. P. F.; Piel, M.; Lennon-Dumenil, A.-M.
10.1101/2022.08.09.503223 — cell biology — Posted on 2023-03-02
4472 metaGE: Investigating Genotype-by-Environment interactions through meta-analysis
De Walsche, A.; Vergne, A.; Rincent, R.; Roux, F.; Nicolas, S. D.; Welcker, C.; Mezmouk, S.; Charcosset, A.; Mary-Huard, T.
10.1101/2023.03.01.530237 — plant biology — Posted on 2023-03-02
4479 Medium depth influences O2 availability and metabolism in cultured RPE cells
Hass, D. T.; Zhang, Q.; Autterson, G.; Bryan, R.; Hurley, J. B.; Miller, J. M.
10.1101/2023.03.01.530623 — cell biology — Posted on 2023-03-02
4481 Monocarboxylate transporters facilitate succinate uptake into brown adipocytes
Reddy, A.; Winther, S.; Tran, N.; Xiao, H.; Jakob, J.; Garrity, R.; Smith, A.; Mills, E.; Chouchani, E.
10.1101/2023.03.01.530625 — cell biology — Posted on 2023-03-02
4483 Probabilistic inference of epigenetic age acceleration from cellular dynamics
Dabrowski, J. K.; Yang, E. J.; Crofts, S. J. C.; Hillary, R. F.; Simpson, D. J.; Mccartney, D. L.; Marioni, R. E.; Latorre-Crespo, E.; Chandra, T.
10.1101/2023.03.01.530570 — cell biology — Posted on 2023-03-02
4485 Crosstalk between Rac and Rho GTPase activity mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
Nanda, S.; Calderon, A.; Duong, T.-T.; Koch, J.; Sachan, A.; Xin, X.; Solouk, D.; Wu, Y.-W.; Nalbant, P.; Dehmelt, L.
10.1101/2023.02.20.529203 — cell biology — Posted on 2023-03-02
4486 Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA
Singh, S.; Gaur, A.; Kumari, R.; Prakash, S.; Kumari, S.; Chaudhary, A. D.; Sharma, R. K.; Prasun, P.; Pant, P.; Thum, T.; Jagavelu, K.; Bharati, P.; Hanif, K.; Chitkara, P.; Kumar, S.; Mitra, K.; Gupta, S. K.
10.1101/2023.03.01.530580 — cell biology — Posted on 2023-03-02
4487 Actin-microtubule crosstalk imparts stiffness to the contractile ring in fission yeast.
Bellingham-Johnstun, K.; Tyree, Z. L.; Martinez-Baird, J.; Thorn, A.; Laplante, C.
10.1101/2023.03.01.530611 — cell biology — Posted on 2023-03-02
4488 Regulatory sites in the Mon1-Ccz1 complex control Rab5 to Rab7 transition and endosome maturation
Borchers, A.-C.; Janz, M.; Schaefer, J.-H.; Moeller, A.; Kuemmel, D.; Paululat, A.; Ungermann, C.; Langemeyer, L.
10.1101/2023.03.01.530579 — cell biology — Posted on 2023-03-02
4489 A conserved pressure-driven mechanism for regulating cytosolic osmolarity
Velle, K. B.; Garner, R. M.; Beckford, T. K.; Weeda, M.; Liu, C.; Kennard, A. S.; Edwards, M.; Fritz-Laylin, L. K.
10.1101/2023.03.01.529730 — cell biology — Posted on 2023-03-02
4490 Chemically Tunable FOXM1-D Sensor Revealed FOXM1 Direct Influence on Cell Cycle
Phongkitkarun, K.; Chusorn, P.; Kamkaew, M.; Lam, E. W.- F.; Promptmas, C.; Sampattavanich, S.
10.1101/2023.03.01.530713 — cell biology — Posted on 2023-03-02
4491 Spatiotemporal cell landscape of human embryonic tooth development
Shi, Y.; Sun, S.; Li, J.; Wang, S.; Yu, Y.; Guo, K.; Yang, J.; Han, L.; Wei, W.; Qiu, J.
10.1101/2023.03.01.530693 — cell biology — Posted on 2023-03-02
4492 The smORF-containing gene mille-pattes is required for moulting and Trypanosoma cruzi metacyclogenesis in the Chagas disease vector Rhodnius prolixus
Azevedo, C.; Alves, S.; Rodrigues, B.; Anderson Fraga Egidio, J.; Ribeiro, L.; Logullo, C.; Mury, F.; Roberto-Silva, J.; Nepomuceno, J.; Nunes-da-Fonseca, R.
10.1101/2020.10.06.324897 — molecular biology — Posted on 2023-03-02
4493 African army ants at the forefront of virome surveillance in a remote tropical forest
Fritz, M.; Reggiardo, B.; Filloux, D.; Claude, L.; Fernandez, E.; Mahe, F.; Kraberger, S.; Custer, J. M.; Becquart, P.; Ndong Mebaley, T.; Bohou Kombila, L.; Lenguiya, L. H.; Boundenga, L.; Mombo, I. M.; Maganga, G. D.; Niama, F. R.; Koumba, J.-S.; Ogliastro, M.; Yvon, M.; Martin, D.; Blanc, S.; Varsani, A.; Leroy, E.; Roumagnac, P.
10.1101/2022.12.13.520061 — microbiology — Posted on 2023-03-02
4494 Enhanced protein synthesis is a defining requirement for neonatal B cell development
Akerstrand, H.; Boldrin, E.; Montano, G.; Vanhee, S.; Olsson, K.; Krausse, N.; Vergani, S.; Ciesla, M.; Bellodi, C.; Yuan, J.
10.1101/2022.11.11.515795 — immunology — Posted on 2023-03-02
4498 Variation and process of life history evolution in insular dwarfism as revealed by a natural experiment
Hayashi, S.; Kubo, M. O.; Sanchez-Villagra, M. R.; Taruno, H.; Izawa, M.; Shiroma, T.; Nakano, T.; Fujita, M.
10.1101/2020.12.23.424186 — evolutionary biology — Posted on 2023-03-02
4500 A ubiquitous spectrolaminar motif of local field potential power across the primate cortex
Mendoza-Halliday, D.; Major, A. J.; Lee, N.; Lichtenfeld, M.; Carlson, B.; Mitchell, B.; Meng, P. D.; Xiong, Y.; Westerberg, J. A.; Maier, A.; Desimone, R.; Miller, E. K.; Bastos, A. M.
10.1101/2022.09.30.510398 — neuroscience — Posted on 2023-03-02
4502 Predictors for Estimating Subcortical EEG Responses to Continuous Speech
Kulasingham, J. P.; Bachmann, F. L.; Eskelund, K.; Enqvist, M.; Alickovic, E.; Innes-Brown, H.
10.1101/2023.03.01.530635 — neuroscience — Posted on 2023-03-01
4504 Cerebellar Activity in PINK1 Knockout Rats during Volitional Gait
DeAngelo, V.; Hilliard, J. D.; Chiang, C.-H.; Viventi, J.; McConnell, G. C.
10.1101/2023.02.28.530534 — neuroscience — Posted on 2023-03-01
4507 The Human Brain Connectome Weighted by the Myelin Content and Total Intra-Axonal Cross-Sectional Area of White Matter Tracts
Nelson, M. C.; Royer, J.; Leppert, I. R.; Campbell, J. S. W.; Schiavi, S.; Jin, H.; Tavakol, S.; Vos de Wael, R.; Rodriguez-Cruces, R.; Pike, G. B.; Bernhardt, B.; Daducci, A.; Misic, B.; Tardif, C. L.
10.1101/2023.03.01.530710 — neuroscience — Posted on 2023-03-02
4509 Exploring neural tracking of acoustic and linguistic speech representations in individuals with post-stroke aphasia
Kries, J.; De Clercq, P.; Gillis, M.; Vanthornhout, J.; Lemmens, R.; Francart, T.; Vandermosten, M.
10.1101/2023.03.01.530707 — neuroscience — Posted on 2023-03-02
4510 Brain-wide neural activity underlying memory-guided movement
Chen, S.; Liu, Y.; Wang, Z.; Colonell, J.; Liu, L. D.; Hou, H.; Tien, N.-W.; Wang, T.; Harris, T.; Druckmann, S.; Li, N.; Svoboda, K.
10.1101/2023.03.01.530520 — neuroscience — Posted on 2023-03-02
4511 Human synaptic neoteny requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition
Libe-Philippot, B.; Iwata, R.; Recupero, A. J.; Wierda, K.; Ditkowska, M.; Gaspariunaite, V.; Vermaercke, B.; Peze-Heidsieck, E.; Remans, D.; Charrier, C.; Polleux, F.; Vanderhaeghen, P.
10.1101/2023.03.01.530630 — neuroscience — Posted on 2023-03-02
4514 BrainLine: An Open Pipeline for Connectivity Analysis of Heterogeneous Whole-Brain Fluorescence Volumes
Athey, T.; Wright, M.; Pavlovic, M.; Chandrashekhar, V.; Deisseroth, K.; Miller, M.; Vogelstein, J.
10.1101/2023.02.28.530429 — bioengineering — Posted on 2023-03-01
4516 Dispensing with unnecessary assumptions in population genetics analysis
Labayle, O.; Tetley-Campbell, K. J.; van der Laan, M. J.; Ponting, C. P.; Beentjes, S. V.; Khamseh, A.
10.1101/2022.09.12.507656 — genetics — Posted on 2023-03-01
4517 Carbon isotope fractionation by an ancestral rubisco suggests biological proxies for CO2 through geologic time should be re-evaluated
Wang, R. Z.; Nichols, R. J.; Liu, A. K.; Flamholz, A. I.; Artier, J.; Banda, D. M.; Savage, D. F.; Eiler, J. M.; Shih, P. M.; Fischer, W. W.
10.1101/2022.06.22.497258 — evolutionary biology — Posted on 2023-03-01
4522 Predicting developmental relationships of tumor resident and circulating T cells in ovarian cancer
dos Santos Carneiro, M.; Bareche, Y.; Zhao, C.; Thebault, P.; Rahimi, K.; Provenche, D.; Samouelian, V.; Cormier, B.; Cailhier, J.-F.; Mes-Masson, A.-M.; Petropoulos, S.; Stagg, J.; Lapointe, R.
10.1101/2023.02.28.530488 — immunology — Posted on 2023-03-01
4523 Molecular basis for potent B cell responses to antigen displayed on particles of viral size
Brooks, J. F.; Riggs, J.; Mueller, J. L.; Mathenge, R.; Wholey, W.-Y.; Yoda, S.-T.; Vykunta, V.; Cheng, W.; Zikherman, J.
10.1101/2023.02.15.528761 — immunology — Posted on 2023-03-01
4528 BDNF signaling in correlation-dependent structural plasticity in the developing visual system
Kutsarova, E.; Schohl, A.; Munz, M.; Wang, A.; Zhang, Y. Y.; Bilash, O. M.; Ruthazer, E. S.
10.1101/2021.10.07.463583 — neuroscience — Posted on 2023-03-01
4536 Evaluation of non-modified wireframe DNA origami for acute toxicity and biodistribution in mice
Wamhoff, E.-C.; Knappe, G. A.; Burds, A. A.; Du, R. R.; Neun, B.; Difilippantonio, S.; Sanders, C.; Edmondson, E.; Matta, J. L.; Dobrovolskaia, M.; Bathe, M.
10.1101/2023.02.25.530026 — pharmacology and toxicology — Posted on 2023-03-01
4537 Isolation and Characterization of Porcine Endocardial Endothelial Cells
Brown, K. N.; Phan, K.; Jui, E. L.; Kang, M. K.; Connell, J. P.; Keswani, S. G.; Grande-Allen, K. J.
10.1101/2022.12.04.518781 — pathology — Posted on 2023-03-01
4539 ClockBase: a comprehensive platform for biological age profiling in human and mouse
Ying, K.; Tyshkovskiy, A.; Trapp, A.; Liu, H.; Moqri, M.; Kerepesi, C.; Gladyshev, V. N.
10.1101/2023.02.28.530532 — bioinformatics — Posted on 2023-03-01
4540 Brain Organoid Computing for Artificial Intelligence
Cai, H.; Ao, Z.; Tian, C.; Wu, Z.; Liu, H.; Tchieu, J.; Gu, M.; Mackie, K.; Guo, F.
10.1101/2023.02.28.530502 — bioengineering — Posted on 2023-03-01
4543 Linking metabolic scaling and coexistence theories
Saavedra, S.; Arroyo, J. I.; Marquet, P.; Kempes, C.
10.1101/2023.02.28.530509 — ecology — Posted on 2023-03-01
4544 Inhibition of hyaluronan synthesis prevents β-cell loss in obesity-associated type 2 diabetes
Nagy, N.; Kaber, G.; Sunkari, V.; Marshall, P. L.; Hargil, A.; Kuipers, H. F.; Ishak, H.; Bogdani, M.; Hull, R.; Grandoch, M.; Fischer, J.; McLaughlin, T.; Wight, T.; Bollyky, P.
10.1101/2023.02.28.530522 — immunology — Posted on 2023-03-01
4545 Impact of in vivo cyclic reprogramming on the choroid plexus
Avila Lopez, J.; Abboud, C.; Ibrahim, M.; Rocha Ahumada, J.; Avino, M.; Plourde, M.; Fernandes, K.; Bentzinger, C. F.; Laurent, B.
10.1101/2023.02.28.530533 — neuroscience — Posted on 2023-03-01
4549 Aging Atlas Reveals Cell-Type-Specific Regulation of Pro-longevity Strategies
Gao, S. M.; Qi, Y.; Zhang, Q.; Mohammed, A. S.; Lee, Y.-T.; Guan, Y.; Li, H.; Fu, Y.; Wang, M. C.
10.1101/2023.02.28.530490 — developmental biology — Posted on 2023-03-01
4551 Evaluating The Efficacy Of Endotracheal Epinephrine Administration At Standard Versus High Dose During Resuscitation Of Severely Asphyxiated Newborn Lambs: A Randomized Preclinical Study
Polglase, G. R.; Brian, Y.; Tantanis, D.; Blank, D. A.; Badurdeen, S.; Crossley, K. J.; Kluckow, M.; Gill, A.; Camm, E.; Galinsky, R.; Songstad, N. T.; Klingenberg, C.; Hooper, S. B.; Roberts, C.
10.1101/2023.02.28.530542 — physiology — Posted on 2023-03-01
4553 DNA nanopores as artificial membrane channels for origami based bioelectronics
Luo, L.; Manda, S.; Park, Y.; Demir, B.; Vicente, J.; Anantram, M. P.; Oren, E. E.; Gopinath, A.; Rolandi, M.
10.1101/2023.03.01.530356 — bioengineering — Posted on 2023-03-01
4554 Small molecule screen identifies non-catalytic USP3 chemical handle
Mann, M. K.; Mirabi, B.; Lautens, M.; Harding, R. J.; Schapira, M.
10.1101/2023.03.01.530657 — biochemistry — Posted on 2023-03-01
4555 Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii
Jonkergouw, C.; Beyeh, N. K.; Osmekhina, E.; Leskinen, K.; Taimoory, S. M.; Fedorov, D.; Anaya-Plaza, E.; Kostiainen, M. A.; Trant, J. F.; Ras, R. H. A.; Saavalainen, P.; Linder, M. B.
10.1101/2023.03.01.530582 — biochemistry — Posted on 2023-03-01
4557 Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids
Bai, J.; Koos, D. S.; Stepanian, K.; Fouladian, Z.; Shayler, D. W. H.; Aparicio, J. G.; Fraser, S. E.; Moats, R. A.; Cobrinik, D.
10.1101/2023.02.28.530518 — developmental biology — Posted on 2023-03-01
4558 Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins
Schmidt, A.; Finegan, T.; Haring, M.; Kong, D.; Fletcher, A. G.; Alam, Z.; Grosshans, J.; Wolf, F.; Peifer, M.
10.1101/2023.03.01.530634 — cell biology — Posted on 2023-03-01
4560 Heat inactivation of foetal bovine serum causes protein contamination of extracellular vesicles
Urzi, O.; Moschetti, M.; Lasser, C.; Johansson, J.; D'Arrigo, D.; Olofsson Bagge, R.; Crescitelli, R.
10.1101/2023.03.01.530627 — cell biology — Posted on 2023-03-01
4561 Bulk RNA-Sequencing of small airway cell cultures from IPF and post-COVID lung fibrosis patients illustrates disease signatures and differential responses to TGF-β1 treatment
Uhl, K.; Paithankar, S.; Leshchiner, D.; Jager, T.; Abdelgied, M.; Tripp, K.; Peraino, A.; Kakazu, M.; Lawson, C.; Chesla, D.; Prokop, J.; Chen, B.; Murphy, E.; Girgis, R.; Li, X.
10.1101/2023.03.01.530431 — cell biology — Posted on 2023-03-01
4563 Transcriptional buffering and 3'UTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load
Mufteev, M.; Rodrigues, D. C.; Yuki, K. E.; Narula, A.; Wei, W.; Piekna, A.; Liu, J.; Pasceri, P.; Rissland, O. S.; Wilson, M. D.; Ellis, J.
10.1101/2023.03.01.530249 — molecular biology — Posted on 2023-03-01
4566 ARF-family global interactome mapping uncovers spatial organization of cellular signaling pathways
Quirion, L.; Robert, A.; Boulais, J.; Huang, S.; Kherdjemil, Y.; Thibault, M.-P.; Faubert, D.; Kmita, M.; Baskin, J. M.; Gingras, A.-C.; Smith, M. J.; Cote, J.-F.
10.1101/2023.03.01.530598 — molecular biology — Posted on 2023-03-01
4569 Development and validation of an experimental life support system to study the impact of ultraviolet B radiation and temperature on coral reef microbial communities
Stuij, T. M.; Cleary, D. F. R.; Rocha, R. J. M.; Polonia, A. R. M.; Silva, D. A. M.; Frommlet, J. C.; Louvado, A.; Huang, Y. M.; van der Windt, N.; de Voogd, N. J.; Gomes, N. C. M.
10.1101/2023.03.01.530425 — microbiology — Posted on 2023-03-01
4571 An intact amber-free HIV-1 system for in-virus protein bioorthogonal click labeling that delineates envelope conformational dynamics
Ao, Y.; Grover, J. R.; Han, Y.; Zhong, G.; Qin, W.; Ghimire, D.; Haque, M. A.; Bhattacharjee, R.; Zhang, B.; Arthos, J.; Lemke, E. A.; Kwong, P. D.; Lu, M.
10.1101/2023.02.28.530526 — microbiology — Posted on 2023-03-01
4572 Chromium/cadmium plays a pivotal role to emerge amoxicillin resistant Staphylococcus aureus
Islam, T. N.; Meem, F. S.; Yasmin, R.; Amin, M. B.; Rahman, T.; Dockrell, D. H.; Mohasin, M.
10.1101/2023.02.28.530213 — microbiology — Posted on 2023-03-01
4573 Inhibition of broomrape germination by 2,4-diacetylphloroglucinol produced by environmental Pseudomonas.
Lurthy, T.; Perot, S.; Gerin-Eveillard, F.; Rey, M.; Wisniewski-Dye, F.; Vacheron, J.; Prigent-Combaret, C.
10.1101/2023.03.01.529533 — microbiology — Posted on 2023-03-01
4574 Humoral and T-cell-mediated responses to a pre-clinical Zika vaccine candidate that utilizes a unique insect-specific flavivirus platform
Porier, D. L.; Adam, A.; Kang, L.; Michalak, P.; Tupik, J.; Santos, M. A.; Lee, C.; Allen, I. C.; Wang, T.; Auguste, A. J.
10.1101/2023.03.01.530296 — microbiology — Posted on 2023-03-01
4575 Type I interferon signaling induces a delayed antiproliferative response in Calu-3 cells during SARS-CoV-2 infection
Cunha, J. B.; Leix, K.; Sherman, E. J.; Mirabelli, C.; Kennedy, A. A.; Lauring, A. S.; Tai, A. W.; Wobus, C. E.; Emmer, B. T.
10.1101/2023.02.28.530557 — microbiology — Posted on 2023-03-01
4576 COVID-19 adenoviral vector vaccination elicits a robust memory B cell response with the capacity to recognize Omicron BA.2 and BA.5 variants
Fryer, H. A.; Hartley, G. E.; Edwards, E. S. J.; Varese, N.; Boo, I.; Bornheimer, S. J.; Hogarth, P. M.; Drummer, H. E.; O'Hehir, R. E.; van Zelm, M. C.
10.1101/2023.02.28.530547 — immunology — Posted on 2023-03-01
4577 IgG4 serum levels are not elevated in cases of Post-COVID syndrome
Abel, J.; Walter, A. J.; Glueck, V.; Magnus, C. L.; Glueck, T.; Schuster, P.; Blaas, S.; Montanari, I.; Koller, M.; Mohr, A.; Hinterberger, T.; Salzberger, B.; Renner, K.; Mack, M.; Bals, R.; Schmidt, T.; Klemis, V.; Sester, M.; Kardashi, R.; de With, K.; Loew, T. H.; Malfertheiner, M.; Pfeifer, M.; Gessner, A.; Schmidt, B.; Schmalenberger, D.; Peterhoff, D.
10.1101/2023.03.01.530454 — immunology — Posted on 2023-03-01
4578 Cryo-EM-guided engineering of T-box-tRNA modules with enhanced selectivity and sensitivity in translational regulation
Jia, X.; Zhang, C.; Luo, B.; Frandsen, J. K.; Watkins, A. M.; Li, K.; Zhang, M.; Wei, X.; Yang, Y.; Henkin, T. M.; Su, Z.
10.1101/2023.02.28.530422 — synthetic biology — Posted on 2023-03-01
4581 Importance of genetic architecture in marker selection decisions for genomic prediction
Della Coletta, R.; Fernandes, S.; Monnahan, P.; Mikel, M.; Bohn, M. O.; Lipka, A. E.; Hirsch, C.
10.1101/2023.02.28.530521 — plant biology — Posted on 2023-03-01
4583 Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy
Niemi, N. M.; Serrano, L. R.; Muehlbauer, L. K.; Balnis, C.; Kozul, K.-L.; Rashan, E. H.; Shishkova, E.; Schueler, K. L.; Keller, M. P.; Attie, A. D.; Pagan, J.; Coon, J. J.; Pagliarini, D. J.
10.1101/2023.02.28.530351 — biochemistry — Posted on 2023-03-01
4585 Far From Home: Evolution of haploid and diploid populations reveals common, strong, and variable pleiotropic effects in non-home environments
Chen, V. K.; Johnson, M. S.; Herissant, L.; Humphrey, P. T.; Yuan, D. C.; Li, Y.; Agarwala, A.; Hoelscher, S. B.; Petrov, D.; Desai, M. M.; Sherlock, G. J.
10.1101/2023.02.28.530341 — evolutionary biology — Posted on 2023-03-01
4586 A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling
Khatib, T. O.; Amanso, A. M.; Pedro, B.; Knippler, C. M.; Summerbell, E. R.; Zohbi, N. M.; Konen, J. M.; Mouw, J. K.; Marcus, A. I.
10.1101/2023.02.28.530493 — cell biology — Posted on 2023-03-01
4591 Uncovering and mitigating bias in large, automated MRI analyses of brain development
Elyounssi, S.; Kunitoki, K.; Clauss, J. A.; Laurent, E.; Kane, K.; Hughes, D. E.; Hopkinson, C. E.; Bazer, O.; Sussman, R. F.; Doyle, A. E.; Lee, H.; Tervo-Clemmens, B.; Eryilmaz, H.; Gollub, R. L.; Barch, D. M.; Satterthwaite, T. D.; Dowling, K. F.; Roffman, J. L.
10.1101/2023.02.28.530498 — neuroscience — Posted on 2023-03-01
4592 Modeling functional cell types in spike train data
Zdeblick, D. N.; Shea-Brown, E. T.; Witten, D. M.; Buice, M. A.
10.1101/2023.02.28.530327 — neuroscience — Posted on 2023-03-01
4594 Scalable Solar-Driven Chemical Production by Semiconductor Biohybrids Synthesized from Wastewater Pollutants
Pi, S.; Yang, W.; Feng, W.; Yang, R.; Chao, W.; Cheng, W.; Cui, L.; Li, Z.; Lin, Y.; Yang, C.; Lu, L.; Gao, X.
10.1101/2023.02.28.530441 — synthetic biology — Posted on 2023-03-01
4595 MEDIPIPE: an automated and comprehensive pipeline for cfMeDIP-seq data quality control and analysis
Zeng, Y.; Ye, W.; Stutheit-Zhao, E. Y.; Han, M.; Bratman, S. V.; Pugh, T. J.; He, H. H.
10.1101/2023.02.28.530481 — bioinformatics — Posted on 2023-03-01
4596 A data-efficient deep learning tool for scRNA-Seq label transfer in neuroscience
Lehrer, J.; Gonzalez-Ferrer, J.; Haussler, D.; Teodorescu, M.; Jonsson, V. D.; Mostajo-Radji, M. A.
10.1101/2023.02.28.529615 — bioinformatics — Posted on 2023-03-01
4599 A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa
Neumayer, G.; Torkelson, J.; Li, S.; McCarthy, K.; Zhen, H.; Vangipuram, M.; Jackow, J.; Rami, A.; Hansen, C.; Guo, Z.; Gaddam, S.; Pappalardo, A.; Li, L.; Cramer, A.; Roy, K.; Nguyen, T. M.; Tanabe, K.; McGrath, P.; Bruckner, A.; Bilousova, G.; Roop, D.; Bailey, I.; Tang, J.; Christiano, A.; Steinmetz, L.; Wernig, M.; Oro, A. E.
10.1101/2023.02.28.529447 — bioengineering — Posted on 2023-03-01
4600 Genome instability footprint under rapamycin and hydroxyurea treatments
Li, J.; Stenberg, S.; Yue, J.-X.; Thompson, D.; Mikhalev, E.; Warringer, J.; Liti, G.
10.1101/2023.02.28.530484 — genomics — Posted on 2023-03-01
4601 Data-driven design of a tool to promote the investigation of understudied genes
Richardson, R. A. K.; Tejedor Navarro, H.; Amaral, L. A. N.; Stoeger, T.
10.1101/2023.02.28.530483 — genomics — Posted on 2023-03-01
4602 Atypical cell death in the growth plate chondrocytes of Tric-b-knockout mice
Ichimura, A.; Miyazaki, Y.; Nagatomo, H.; Tomizawa, M.; Kawabe, T.; Nakajima, N.; Okamoto, N.; Komazaki, S.; Kakizawa, S.; Nishi, M.; Takeshima, H.
10.1101/2023.02.28.530410 — developmental biology — Posted on 2023-03-01
4603 Olfactory and neuropeptide inputs to appetite neurons in the arcuate nucleus
Kuang, D.; Hanchate, N. K.; Lee, C.-Y.; Heck, A.; Ye, X.; Erdenebileg, M.; Buck, L. B.
10.1101/2023.02.28.530282 — neuroscience — Posted on 2023-03-01
4604 Genetic Predisposition to Neuroblastoma Results from a Regulatory Polymorphism that Promotes the Adrenergic Cell State
Weichert-Leahey, N.; Shi, H.; Tao, T.; Oldridge, D.; Durbin, A.; Abraham, B.; Zimmerman, M.; Zhu, S.; Wood, A.; Reyon, D.; Joung, J. K.; Young, R.; Diskin, S. J.; Maris, J.; Look, A. T.
10.1101/2023.02.28.530457 — cancer biology — Posted on 2023-03-01
4609 Evaluating Prompt Tuning for Conditional Protein Sequence Generation
Nathansen, A.; Klein, K.; Renard, B. Y.; Nowicka, M.; Bartoszewicz, J. M.
10.1101/2023.02.28.530492 — bioinformatics — Posted on 2023-03-01
4610 BrainLine: An Open Pipeline for Connectivity Analysis of Heterogeneous Whole-Brain Fluorescence Volumes
Athey, T.; Wright, M.; Pavlovic, M.; Chandrashekhar, V.; Deisseroth, K.; Miller, M.; Vogelstein, J.
10.1101/2023.02.28.530429 — bioengineering — Posted on 2023-03-01
4611 Comparative analysis of amphibian genomes: an emerging resource for basic and applied research
Kosch, T. A.; Crawford, A. J.; Mueller, R. L.; Wollenberg Valero, K. C.; Rodriguez, A.; O'Connell, L. A.; Young, N. D.; Skerratt, L. F.
10.1101/2023.02.27.530355 — genomics — Posted on 2023-03-01
4613 Single cell transcriptomics reveals early photoreceptor trajectories and a cancer-predisposed cone precursor state
Shayler, D. W. H.; Stachelek, K.; Lee, S.; Bai, J.; Reid, M. W.; Aparicio, J. G.; Kim, Y.; Singh, M.; Bay, M.; Thornton, M. E.; Grubbs, B. H.; Bonaguidi, M. A.; Craft, C. M.; Singh, H. P.; Cobrinik, D.
10.1101/2023.02.28.530247 — developmental biology — Posted on 2023-03-01
4614 GIPC3 couples to MYO6 and PDZ domain proteins and shapes the hair cell apical region
Chatterjee, P.; Morgan, C. P.; Krey, J. F.; Benson, C.; Goldsmith, J.; Bateschell, M.; Ricci, A.; Barr-Gillespie, P. G.
10.1101/2023.02.28.530466 — cell biology — Posted on 2023-03-01
4617 Type 1 immunity enables neonatal thymic ILC1 production
Tougaard, P.; Perez, M. R.; Steels, W.; Huysentruyt, J.; Verstraeten, B.; Vetters, J.; Divert, T.; Goncalves, A.; Roelandt, R.; Takahashi, N.; Janssens, S.; Buus, T. B.; Taghon, T.; Leclercq, G.; Vandenabeele, P.
10.1101/2023.02.28.530451 — immunology — Posted on 2023-03-01
4623 Cerebellar Activity in Hemi-Parkinsonian Rats during Volitional Gait and Freezing
DeAngelo, V.; Gehan, A.; Paliwal, S.; Ho, K.; Hilliard, J. D.; Chiang, C.-H.; Viventi, J.; McConnell, G. C.
10.1101/2023.02.28.530475 — neuroscience — Posted on 2023-03-01
4624 Tracking the progression of Alzheimer's disease with peripheral blood monocytes
Bavykina, V.; Avino, M.; Husain, M. A.; Zimmer, A.; Parent-Roberge, H.; Khalil, A.; Brunet, M. A.; Fulop, T.; Laurent, B.
10.1101/2023.02.28.530459 — neuroscience — Posted on 2023-03-01
4625 All about urine: Longitudinal examination of urine pH, specific gravity, proteins, culture, and resistance profiles in healthy dogs
McGlynn, A.; Mrofchak, R.; Madan, R.; Madden, C.; Jahid, M. J.; Mollenkopf, D.; Wittum, T. E.; Justice, S.; Rudinsky, A.; Hokamp, J.; Hale, V. L.
10.1101/2023.02.28.530482 — zoology — Posted on 2023-03-01
4626 Adulis and the transshipment of baboons during classical antiquity
Grathwol, F.; Roos, C.; Zinner, D.; Hume, B.; Porcier, S. M.; Berthet, D.; Cuisin, J.; Merker, S.; Ottoni, C.; Van Neer, W.; Dominy, N. J.; Kopp, G. H.
10.1101/2023.02.28.530428 — zoology — Posted on 2023-03-01
4627 Metabolomics investigation of post-mortem human pericardial fluid
Chighine, A.; Stocchero, M.; Ferino, G.; De-Giorgio, F.; Conte, C.; Nioi, M.; d'Aloja, E.; Locci, E.
10.1101/2023.02.28.530436 — systems biology — Posted on 2023-03-01
4628 Agronomic treatments combined with embryo rescue for rapid generation advancement in tomato speed breeding
Gimeno-Paez, E.; Prohens, J.; Moreno-Cervero, M.; de Luis-Margarit, A.; Diez, M. J.; Gramazio, P.
10.1101/2023.02.28.530438 — plant biology — Posted on 2023-03-01
4630 Immature myeloid cells are indispensable for intestinal regeneration post irradiation injury
Jiang, Z.; Waterbury, Q. T.; Fu, N.; Kim, W.; Malagola, E. T.; Guha, C.; Shawber, C. J.; Yan, K. S.; Wang, T. C.
10.1101/2023.02.28.530500 — physiology — Posted on 2023-03-01
4631 Discovery of decreased ferroptosis in male colorectal cancer patients with KRAS mutations
Yan, H.; Talty, R.; Jain, A.; Cai, Y.; Zheng, J.; Shen, X.; Muca, E.; Paty, P.; Bosenburg, M.; Khan, S.; Johnson, C.
10.1101/2023.02.28.530478 — cancer biology — Posted on 2023-03-01
4634 A conserved local structural motif controls the kinetics of PTP1B catalysis
Yeh, C. Y.; Izaguirre, J. A.; Greisman, J. B.; Willmore, L.; Maragakis, P.; Shaw, D. E.
10.1101/2023.02.28.529746 — biophysics — Posted on 2023-03-01
4635 StereoCell enables high accuracy single cell segmentation for spatial transcriptomic dataset
Li, M.; Liu, H.; Li, M.; Fang, S.; Kang, Q.; Zhang, J.; Teng, F.; Wang, D.; Cen, W.; Li, Z.; Feng, N.; Guo, J.; He, Q.; Wang, L.; Zheng, T.; Li, S.; Bai, Y.; Xie, M.; Bai, Y.; Liao, S.; Chen, A.; Xu, X.; Zhang, Y.; Li, Y.
10.1101/2023.02.28.530414 — bioinformatics — Posted on 2023-03-01
4636 Bearded or Smooth? Awns Improve Yield when Wheat Experiences Heat Stress During Grain Fill
DeWitt, N.; Lyerly, J.; Guedira, M.; Holland, J. B.; Murphy, J. P.; Ward, B. P.; Boyles, R. E.; Mergoum, M.; Babar, M. A.; Shakiba, E.; Sutton, R.; Ibrahim, A.; Tiwari, V. K.; Santantonio, N.; Van Sanford, D. A.; Howell, K.; Smith, J. H.; Harrison, S. A.; Brown-Guedira, G.
10.1101/2023.02.27.530138 — genetics — Posted on 2023-03-01
4639 Mice with renal-specific alterations of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors
Myszczyszyn, A.; Popp, O.; Kunz, S.; Sporbert, A.; Jung, S.; Penning, L. C.; Fendler, A.; Mertins, P.; Birchmeier, W.
10.1101/2023.02.28.530413 — cell biology — Posted on 2023-03-01
4641 SARS-CoV-2 ORF3c suppresses immune activation by inhibiting innate sensing
Mueller, M.; Herrmann, A.; Fujita, S.; Kolberg, E. J.; Kruth, C.; Stange, A.; Schneider, M.; Ito, J.; Ensser, A.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Sato, K.; Sauter, D.
10.1101/2023.02.27.530232 — microbiology — Posted on 2023-03-01
4642 Tozorakimab (MEDI3506): a dual-pharmacology anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
England, E.; Rees, D. G.; Scott, I. C.; Carmen, S.; Chan, D. T. Y.; Huntington, C. E. C.; Houslay, K. F.; Erngren, T.; Penney, M.; Majithiya, J. B.; Rapley, L.; Sims, D. A.; Hollins, C.; Hinchy, E. C.; Strain, M. D.; Kemp, B. P.; Corkill, D. J.; May, R. D.; Vousden, K. A.; Butler, R. J.; Mustelin, T.; Vaughan, T. J.; Lowe, D. C.; Colley, C.; Cohen, E. S.
10.1101/2023.02.28.527262 — immunology — Posted on 2023-03-01
4643 HIV-differentiated metabolite N-Acetyl-L-Alanine dysregulates human natural killer cell responses to Mycobacterium tuberculosis infection
Yang, B.; Mukherjee, T.; Radhakrishnan, R.; Paidipally, P.; Ansari, D.; John, S.; Vankayalapati, R.; Tripathi, D.; Yi, G.
10.1101/2023.02.28.530445 — immunology — Posted on 2023-03-01
4644 Myeloid Zfhx3 Deficiency Protects Against Hypercapnia-induced Suppression of Host Defense Against Influenza A Virus
Casalino-Matsuda, S. M.; Chen, F.; Gonzalez-Gonzalez, F. J.; Matsuda, H.; Nair, A.; Abdala-Valencia, H.; Budinger, G. R. S.; Dong, J.-T.; Beitel, G.; Sporn, P. H. S.
10.1101/2023.02.28.530480 — immunology — Posted on 2023-03-01
4647 Improved spatial knowledge acquisition through sensory augmentation
Schmidt, V.; Konig, S. U.; Dilawar, R.; Sanchez-Pacheco, T. L.; Konig, P.
10.1101/2023.02.28.530376 — neuroscience — Posted on 2023-03-01
4649 An analogue of the Prolactin Releasing Peptide reduces obesity and promotes adult neurogenesis
Jorgensen, S. K. M.; Karnosova, A.; Mazzaferro, S.; Chen, H.-J. C.; Robbins, S. J.; Christofides, S.; Merkle, F. T.; Maletinska, L.; Petrik, D.
10.1101/2023.02.28.528936 — neuroscience — Posted on 2023-03-01
4650 Blood neurofilament light chain levels are associated with disease progression in a transgenic SCA3 mouse model
Mengel, D.; Wellik, I. G.; Schuster, K. H.; Jarrah, S. I.; Wacker, M.; Ashraf, N. S.; Oz, G.; Synofzik, M.; Costa, M. d. C.; McLoughlin, H. S.
10.1101/2023.02.28.530463 — neuroscience — Posted on 2023-03-01
4651 CBD lengthens sleep, shortens ripples and leads to intact simple but worse cumulative memory
Samanta, A.; Aleman-Zapata, A.; Agarwal, K.; Ozsezer, P.; Alonso, A.; Van der Meij, J.; Rayan, A.; Navarro Lobato, I.; Genzel, L.
10.1101/2023.02.28.530388 — neuroscience — Posted on 2023-03-01
4652 Unexpected plasma gonadal steroid and reproductive hormone levels across the mouse estrous cycle
Wall, E. G.; Desai, R.; Aung, Z. K.; Yeo, S. H.; Grattan, D. R.; Handelsman, D. J.; Herbison, A. E.
10.1101/2023.02.28.530435 — physiology — Posted on 2023-03-01
4655 Condensate-driven interfacial forces reposition DNA loci and measure chromatin viscoelasticity
Strom, A. R.; Kim, Y.; Zhao, H.; Orlovsky, N. D.; Chang, Y.-C.; Kosmirlj, A.; Storm, C.; brangwynne, C. P.
10.1101/2023.02.27.530281 — biophysics — Posted on 2023-03-01
4660 Multifunctional Materials Strategies for Enhanced Safety of Wireless, Skin-Interfaced Bioelectronic Devices
Liu, C.; Kim, J.-T.; Yang, D. S.; Cho, D.; Yoo, S.; Madhvapathy, S. R.; Jeong, H.; Yang, T.; Luan, H.; Avila, R.; Park, J.; Wu, Y.; Bryant, K.; Cho, M.; Lee, J.; Kwak, J.; Ryu, W.; Huang, Y.; Nuzzo, R. G.; Rogers, J. A.
10.1101/2023.02.28.530037 — bioengineering — Posted on 2023-03-01
4661 Living Photovoltaics based on Recombinant Expression of MtrA Decaheme in Photosynthetic Bacteria
Reggente, M.; Schuergers, N.; Mouhib, M.; Politi, S.; Antonucci, A.; Boghossian, A. A.
10.1101/2023.02.28.530417 — bioengineering — Posted on 2023-03-01
4664 Microhomology-Mediated Circular DNA Formation from Oligonucleosomal Fragments During Spermatogenesis
Hu, J.; Zhang, Z.; Xiao, S.; Cao, Y.; Chen, Y.; Weng, J.; Jiang, H.; Li, W.; Chen, J.-Y.; Liu, C.
10.1101/2023.02.27.530352 — genomics — Posted on 2023-03-01
4665 Metagenome-assembled microbial genomes from Parkinson's disease fecal samples
Duru, I. C.; Lecomte, A.; Shishido, T. K.; Laine, P.; Suppula, J.; Paulin, L.; Scheperjans, F.; Pereira, P. A. B.; Auvinen, P.
10.1101/2023.02.27.526590 — genomics — Posted on 2023-03-01
4671 On the quest for novelty in ecology
Ottaviani, G.; Martinez, A.; Petit Bon, M.; Mammola, S.
10.1101/2023.02.27.530333 — ecology — Posted on 2023-03-01
4674 Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
Harris, R. J.; Heer, M.; Levasseur, M. D.; Cartwright, T. N.; Weston, B.; Mitchell, J. L.; Coxhead, J. M.; Gaughan, L.; Prendergast, L.; Rico, D.; Higgins, J. M. G.
10.1101/2023.02.28.530230 — cell biology — Posted on 2023-03-01
4675 Mesenchymal stromal cells affect CD8 naive to memory subsets polarization by down-modulating IL12beta1 and IL2Ralpha signaling pathways
Papait, A.; Vertua, E.; Bonassi Signoroni, P.; Cargnoni, A.; Magatti, M.; Stefani, F. R.; Romoli, J.; Silini, A. R.; Parolini, O.
10.1101/2023.02.28.530378 — immunology — Posted on 2023-03-01
4676 Liver-specific Inflammatory Signatures Predict Clinically Significant Liver Damage.
Chua, C.; Mahamed, D.; Nkongolo, S.; Mehrotra, A.; Wong, D. K. H.; Chung, R. T.; Feld, J. J.; Janssen, H. L. A.; Gehring, A. J.
10.1101/2023.02.28.530386 — immunology — Posted on 2023-03-01
4679 A biologically plausible decision-making model based on interacting cortical columns
Baspinar, E.; Cecchini, G.; DePass, M.; Andujar, M.; Pani, P.; Ferraina, S.; Moreno-Bote, R.; Cos, I.; Destexhe, A.
10.1101/2023.02.28.530384 — neuroscience — Posted on 2023-03-01
4680 Spontaneous allelic variant in Ush1g resulting in an expanded phenotype
Vartanian, V.; Krey, J. F.; Chatterjee, P.; Jones, S. M.; Curtis, A.; Ryals, R.; Lloyd, R. S.; Barr-Gillespie, P. G.
10.1101/2023.02.28.529432 — neuroscience — Posted on 2023-03-01
4683 Systematic Identification of Post-Transcriptional Regulatory Modules
Khoroshkin, M. S.; Buyan, A.; Dodel, M.; Navickas, A.; Yu, J.; Trejo, F.; Doty, A.; Baratam, R.; Zhou, S.; Joshi, T.; Miglani, S.; Choi, B.; Subramanyam, V.; Modi, H.; Corces, R.; Markett, D.; Kulakovskiy, I. V.; Mardakheh, F. K.; Goodarzi, H.
10.1101/2023.02.27.530345 — systems biology — Posted on 2023-03-01
4685 Rhythm generating mechanisms in rat sino-atrial node and ventricle
Charles, J.; Nedumaran, L.; Raman, S.; Vinod, E.; Rajasegaran, R.; Vadivel, K.; Bhaskar, A.; Subramani, S.
10.1101/2023.02.28.529494 — physiology — Posted on 2023-03-01
4687 Leveraging IFNγ/CD38 regulation to unmask and target leukemia stem cells in acute myelogenous leukemia
Murtadha, M.; Park, M.; Zhu, Y.; Caserta, E.; Dona, A. A.; Singer, M.; Vahed, H.; Tandoh, T.; Gonzalez, A.; Ly, K.; Sanchez, J.; Chowdhury, A.; Pozhitkov, A.; Ghoda, L.; Li, L.; Zhang, B.; Krishnan, A.; Marcucci, G.; Williams, J. C.; Pichiorri, F.
10.1101/2023.02.27.530273 — cancer biology — Posted on 2023-03-01
4689 Elucidating Molecular Mechanisms of Protoxin-2 State-specific Binding to the Human NaV1.7 Channel
Ngo, K.; Mateos, D. L.; Rouen, K.; Han, Y.; Wulff, H.; Clancy, C. E.; Yarov-Yarovoy, V.; Vorobyov, I.
10.1101/2023.02.27.530360 — biophysics — Posted on 2023-03-01
4692 Substrate stiffness facilitates improved induced pluripotent stem cell production through modulation of both early and late phases of cell reprogramming
Chowdhury, M. M.; Samuel Zimmerman, S.; Leeson, H.; Nefzger, C.; Mar, J. C.; Laslett, A.; Polo, J. M.; Wolvetang, E. J.; Cooper-White, J. J.
10.1101/2023.02.27.530366 — bioengineering — Posted on 2023-03-01
4693 Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells
Santalla Mendez, R.; Rodgers Furones, A.; Classens, R.; Haverdil, M.; Canela Capdevila, M.; van Duffelen, A.; ter Beest, M.; Spruijt, C. G.; Vermeulen, M.; van Spriel, A. B.; Querol Cano, L.
10.1101/2022.05.13.491792 — cell biology — Posted on 2023-03-01
4694 Evolution within a given virulence phenotype (pathotype) is driven by changes in aggressiveness: a case study of French wheat leaf rust populations
FONTYN, C.; MEYER, K. J.; BOIXEL, A.-L.; DELESTRE, G.; PIAGET, E.; PICARD, C.; SUFFERT, F.; MARCEL, T. C.; GOYEAU, H.
10.1101/2022.08.29.505401 — microbiology — Posted on 2023-03-01
4696 Polarimetric response of second harmonic generation in microscopy of chiral fibrillar structures
Alizadeh, M.; Habach, F.; Maciulis, M.; Kontenis, L.; Bagdonas, S.; Krouglov, S.; Baranauskas, V.; Bulotiene, D.; Karabanovas, V.; Rotomskis, R.; Akens, M. K.; Barzda, V.
10.1101/2023.02.23.529792 — biophysics — Posted on 2023-03-01
4700 A viral ADP-ribosyltransferase attaches RNA chains to host proteins
Wolfram-Schauerte, M.; Pozhydaieva, N.; Grawenhoff, J.; Welp, L. M.; Silbern, I.; Wulf, A.; Billau, F. A.; Glatter, T.; Urlaub, H.; Jäschke, A.; Höfer, K.
10.1101/2021.06.04.446905 — microbiology — Posted on 2023-03-01
4701 Developmentally determined intersectional genetic strategies to dissect adult somatosensory circuit function
Bohic, M.; Upadhyay, A.; Eisdorfer, J. T.; Keating, J. R.; Simon, R.; Briones, B.; Azadegan, C.; Nacht, H.; Oputa, O.; Bethell, B. B.; Romanienko, P. J.; Ramer, M. S.; Stuber, G. D.; Abraira, V. E.
10.1101/2022.05.16.492127 — neuroscience — Posted on 2023-03-01
4702 A Metabolomics Study of Thrombosis after Cardiac Surgery in Children with Congenital Heart Disease
Li, S.; Watson, D.; Jorgenson, A.; Adelekan, Z.; Tang, W.; Garland, K.; Zupancich, L.; Edens, R. E.; Overman, D. M. M.; Huntley, M. T.
10.1101/2023.02.20.529324 — physiology — Posted on 2023-03-01
4705 Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells
Cecon, E.; Oishi, A.; Luka, M.; Ndiaye-Lobry, D.; Francois, A.; Lescuyer, M.; Panayi, F.; Dam, J.; Machado, P.; Jockers, R.
10.1101/2022.03.18.484918 — cell biology — Posted on 2023-03-01
4707 Interferon-induced lysosomal membrane permeabilization and death cause cDC1-deserts in tumors.
Aerakis, E.; Chatzigeorgiou, A.; Alvanou, M.-M.; Matthaiakaki-Panagiotaki, M.; Angelidis, I.; Koumadorakis, D.; Galaras, A.; Hatzis, P.; Kerdidani, D.; Makridakis, M.; Vlahou, A.; Malissen, B.; Henri, S.; Merad, M.; Tsoumakidou, M.
10.1101/2022.03.14.484263 — immunology — Posted on 2023-03-01
4711 A spiking neural network model of cortical intraregional metastability
Venkadesh, S.; Shaikh, A.; Shakeri, H.; Barreto, E.; Van Horn, J. D.
10.1101/2022.09.28.509893 — neuroscience — Posted on 2023-03-01
4713 Conservation implications of elucidating the Korean wolf taxonomic ambiguity through whole-genome sequencing
Hernandez Alonso, G.; Ramos-Madrigal, J.; Sun, X.; Hjorth Scharff-Olsen, C.; Sinding, M.-H. S.; Martins, N. F.; Ciucani, M. M.; Mak, S. S. T.; Lanigan, L. T.; Clausen, C. C.; Bhak, J.; Jeon, S.; Kim, C.; Yeon Eo, K.; Cho, S.-H.; Boldgiv, B.; Gantulga, G.; Unudbayasgalan, Z.; Kosintsev, P. A.; Stenoien, H. K.; Gilbert, M. T. P.; Gopalakrishnan, S.
10.1101/2023.02.24.529912 — evolutionary biology — Posted on 2023-03-01
4714 Multi-species atlas resolves an axolotl limb development and regeneration paradox
Zhong, J.; Aires, R.; Tsissios, G.; Skoufa, E.; Brandt, K.; Sandoval-Guzman, T.; Aztekin, C.
10.1101/2023.03.01.530572 — developmental biology — Posted on 2023-03-01
4717 Clinical Forecasting using Ex Vivo Drug Sensitivity Profiling of Acute Myeloid Leukemia
Andersen, A.; Brodersen, A.; Ayuda-Duran, P.; Piechaczyk, L.; Tadele, D.; Baken, L.; Fredriksen, J.; Stoksflod, M.; Lenartova, A.; Floisand, Y.; Enserink, J.
10.1101/2022.10.11.509866 — bioinformatics — Posted on 2023-03-01
4718 Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse
Muronova, J.; Kherraf, Z. E.; Giordani, E.; Eckert, S.; Cazin, C.; Amiri-Yekta, A.; Lambert, E.; Chevalier, G.; Martinez, G.; Neirijnck, Y.; Kühne, F.; Wehrli, L.; Klena, N.; Hamel, V.; Escoffier, J.; Guichard, P.; Coutton, C.; Mustapha, S. F. B.; Kharouf, M.; Zouari, R.; Thierry-Mieg, N.; Nef, S.; Geimer, S.; Loeuillet, C.; Ray, P. F.; Arnoult, C.
10.1101/2023.02.27.530236 — genetics — Posted on 2023-03-01
4719 Global transcriptional analysis of Geobacter sulfurreducens gsu1771 mutant biofilm grown on two different support structures
Jaramillo-Rodriguez, J. B.; Vega-Alvarado, L.; Rodriguez-Torres, L. M.; Huerta-Miranda, G. A.; Hernandez-Eligio, A.; Juarez, K.
10.1101/2023.02.27.530372 — microbiology — Posted on 2023-03-01
4720 A dynamic bactofilin cytoskeleton recruits an M23 endopeptidase to control bacterial morphogenesis
Osorio-Valeriano, M.; Cserti, E.; Pöhl, S.; Hernandez-Tamayo, R.; Biboy, J.; Sobetzko, P.; Vollmer, W.; Graumann, P. L.; Thanbichler, M.
10.1101/2023.02.27.530196 — microbiology — Posted on 2023-03-01
4723 Shortwave-Infrared Line-Scan Confocal Microscope for Deep Tissue Imaging in Intact Organs
Lingg, J. G. P.; Bischof, T. S.; Rowlands, C. J.; Bruns, O. T.; Chmyrov, A.; Arus, B. A.; Cosco, E. D.; Sletten, E. M.
10.1101/2022.12.23.521760 — bioengineering — Posted on 2023-03-01
4725 Dimensionality and ramping: Signatures of sentence integration in the dynamics of brains and deep language models
Desbordes, T.; Lakretz, Y.; Chanoine, V.; Oquab, M.; Badier, J.-M.; Trebuchon, A.; Caron, R.; Benar, C.; Dehaene, S.; King, J.-R.
10.1101/2023.02.28.530443 — neuroscience — Posted on 2023-03-01
4727 The temporal transcriptomic signature of cartilage formation
Takacs, R. A.; Vago, J.; Poliska, S.; Pushparaj, P. N.; Ducza, L.; Kovacs, P.; Jin, E.-J.; Barrett-Jolley, R.; Zakany, R.; Matta, C.
10.1101/2022.04.01.486765 — molecular biology — Posted on 2023-03-01
4728 UBE3A and transsynaptic complex NRXN1-CBLN1-GluD1 in a hypothalamic VMHvl-arcuate feedback circuit regulates aggression
Nong, Y.; Stoppel, D.; Johnson, M.; Boillot, M.; Todorovic, J.; Shen, J.; Zhou, X.; Nadler, M.; Rodriquez, C.; Huo, Y.; Nagakura, I.; Kasper, E.; Anderson, M.
10.1101/2023.02.28.530462 — neuroscience — Posted on 2023-03-01
4729 Dimensionality and ramping: Signatures of sentence integration in the dynamics of brains and deep language models
Desbordes, T.; Dehaene, S.; Lakretz, Y.; Chanoine, V.; Benar, C.; Badier, J.-M.; Oquab, M.; Caron, R.; Trebuchon, A.; King, J.-R.
10.1101/2023.02.28.530443 — neuroscience — Posted on 2023-03-01
4730 Age but not menopausal status is linked to lower resting energy expenditure
Karppinen, J. E.; Wiklund, P.; Ihalainen, J. K.; Juppi, H.-K.; Isola, V.; Hyvarinen, M.; Ahokas, E. K.; Kujala, U. M.; Laukkanen, J. A.; Hulmi, J. J.; Ahtiainen, J. P.; Cheng, S.; Laakkonen, E. K.
10.1101/2022.12.16.520683 — physiology — Posted on 2023-03-01
4732 Modeling the marmoset brain using embryonic stem cell-derived cerebral assembloids
Kodera, T.; Takeuchi, R. F.; Takahashi, S.; Suzuki, K.; Kassai, H.; Aiba, A.; Shiozawa, S.; Okano, H.; Osakada, F.
10.1101/2023.02.28.530008 — neuroscience — Posted on 2023-03-01