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Archive, 2024-08

2 Inhibition of Soluble Epoxide Hydrolase Ameliorates Cerebral Blood Flow Autoregulation and Cognition in Alzheimer's Disease and Diabetes-Related Dementia Rat Models
Tang, C.; Border, J. J.; Zhang, H.; Gregory, A.; Bai, S.; Fang, X.; Liu, Y.; Wang, S.; Hwang, S. H.; Gao, W.; Morgan, G. C.; Smith, J.; Bunn, D.; Cantwell, C.; Wagner, K. M.; Morisseau, C.; Yang, J.; Shin, S. M.; O'Herron, P.; Bagi, Z.; Filosa, J. A.; Dong, Y.; Yu, H.; Hammock, B. D.; Roman, R. J.; Fan, F.
10.1101/2024.08.30.610540 — molecular biology — Posted on 2024-08-31
3 Chronic social defeat stress induces meningeal neutrophilia via type I interferon signaling
Kigar, S. L.; Lynall, M.-E.; DePuyt, A. E.; Atkinson, R.; Sun, V. H.; Samuels, J. D.; Eassa, N. E.; Poffenberger, C. N.; Lehmann, M. L.; Listwak, S. J.; Livak, F.; Elkahloun, A. G.; Clatworthy, M. R.; Bullmore, E. T.; Herkenham, M.
10.1101/2024.08.30.610447 — neuroscience — Posted on 2024-08-31
4 Deficiency in transmitter release triggers homeostatic transcriptional changes that increase presynaptic excitability
Cypranowska, C. A.; Bakshinska, D.; Feldthouse, M.; Choi, Y. G.; Li, R.; Newman, Z. L.; Isacoff, E. Y.
10.1101/2024.08.30.610173 — neuroscience — Posted on 2024-08-31
9 Velamins: the first green-light emitting class of wild-type Ca2+-regulated photoproteins isolated from the ctenophore Velamen parallelum
Soares, D. M.; Galeazzo, G. A.; Sgro, G. G.; Moraes, G. V.; Kronenberg, L.; Borukh, E.; Migotto, A. E.; Gruber, D. F.; Sparks, J. S.; Pieribone, V. A.; Stevani, C. V.; Oliveira, A. G.
10.1101/2024.08.30.610560 — biochemistry — Posted on 2024-08-31
11 Retention of DLK1 in the endoplasmic reticulum identifies roles for EGF domain-specific O-glycans in the secretory pathway
Tashima, Y.; Tsukamoto, Y.; Tsukamoto, N.; Kondo, Y.; Uddin, E.; Furukawa, W.; Go, S.; Takeuchi, H.; Okajima, T.
10.1101/2024.08.31.610613 — biochemistry — Posted on 2024-08-31
12 Fast variance component analysis using large-scale ancestral recombination graphs
Zhu, J.; Kalantzis, G.; Pazokitoroudi, A.; Gunnarsson, A. F.; Loya, H.; Chen, H.; Sankararaman, S.; Palamara, P. F.
10.1101/2024.08.31.610262 — genetics — Posted on 2024-08-31
15 Diversity and ecological roles of RNA viral communities in the cryosphere of the Tibetan Plateau
Liu, Y.; Zhang, Z.; Jiao, N.; Zhu, Y.; Zhang, R.; Dominguez-Huerta, G.; Wang, H.; Feng, M.; Wen, R.; Ji, M.; Zheng, Q.; Liu, P.; Yao, T.
10.1101/2024.08.30.610425 — ecology — Posted on 2024-08-31
18 Programmed ribosomal frameshifting during PLEKHM2 mRNA decoding generates a constitutively active mediator of kinesin-1-dependent lysosome transport
Khan, Y. A.; De Pace, R.; Jungreis, I.; Carancini, G.; Mudge, J. M.; Kellis, M.; Atkins, J. F.; Baranov, P.; Firth, A.; Bonifacino, J.; Loughran, G.
10.1101/2024.08.30.610563 — molecular biology — Posted on 2024-08-31
19 Dispersal of influenza virus populations within the respiratory tract shapes their evolutionary potential
Ferreri, L.; Seibert, B.; Caceres, J.; Patatanian, K.; Holmes, K. E.; Gay, C.; Faccin, F.; Cardenas Perez, M.; Carnaccini, S.; Shetty, N.; Rajao, D.; Koelle, K.; Marr, L.; Perez, D. R.; Lowen, A. C.
10.1101/2024.08.31.610648 — microbiology — Posted on 2024-08-31
20 Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures
Vieira-Lara, M. A.; Warmerdam, M.; de Hulster, E. A. F.; van den Broek, M.; Daran, J.-M.; Pronk, J. T.
10.1101/2024.08.31.610600 — microbiology — Posted on 2024-08-31
23 Unravelling the Maturation Pathway of a Eukaryotic Virus through Cryo-EM
Castells-Graells, R.; Hesketh, E. L.; Matsui, T.; Johnson, J. E.; Ranson, N. A.; Lawson, D. M.; Lomonossoff, G. P.
10.1101/2024.08.31.610394 — biochemistry — Posted on 2024-08-31
26 Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal
Gray, C. N.; Ashokkumar, M.; Janssens, D. H.; Kirchherr, J. L.; Allard, B.; Hsieh, E.; Hafer, T. L.; Archin, N. M.; Browne, E. P.; Emerman, M.
10.1101/2024.08.30.610517 — microbiology — Posted on 2024-08-31
27 Prodrug activation in malaria parasites mediated by an imported erythrocyte esterase, acylpeptide hydrolase (APEH)
Sundararaman, S. A.; Miller, J. J.; Daley, E. C.; O'Brien, K. A.; Kasak, P.; Daniels, A. M.; Edwards, R. L.; Heidel, K. M.; Bague, D. A.; Wilson, M. A.; Koelper, A. J.; Kourtoglou, E. C.; White, A. D.; August, S. A.; Apple, G. A.; Rouamba, R. W.; Durand, A. J.; Esteb, J. J.; Muller, F. L.; Johnson, R. J.; Hoops, G. C.; Dowd, C. S.; Odom John, A. R.
10.1101/2024.08.30.610542 — microbiology — Posted on 2024-08-31
31 Rationalizing the Effects of RNA Modifications on Protein Interactions
Vandelli, A.; Broglia, L.; Armaos, A.; Delli Ponti, R.; Tartaglia, G. G.
10.1101/2024.08.31.610603 — bioinformatics — Posted on 2024-08-31
33 Developing Biosensors for Specific Assessment of Trans-translation in Pseudomonas aeruginosa.
L'Hermitte, B.; Chauvet, T.; Georgeault Daguenet, S.; Le Yondre, N.; Jehan, P.; Gillet, R.; Baysse, C.
10.1101/2024.08.30.610505 — microbiology — Posted on 2024-08-31
34 A Novel Approach to Reducing Spinal Implant-Associated Infections
Nishizawa, M.; Hu, D.; Serhan, H.; Saleh, B.; Marcucio, R. S.; Morioka, K.
10.1101/2024.08.30.610521 — microbiology — Posted on 2024-08-31
35 Highly pathogenic avian influenza H5 virus exposure in goats and sheep
Wong, F. Y.; Yaqub, T.; Zhang, R.; Mukhtar, N.; Pervaiz, H.; Yawar, H. U. H.; Iqbal, M.; bin Aslam, H.; Aziz, M. W.; Akram, M.; Raza, S.; Low, J. G.; Cronin, P.; Laing, E. D.; Low, D. H.; Webby, R. J.; Su, Y. C.; Smith, G. J.
10.1101/2024.08.31.610397 — microbiology — Posted on 2024-08-31
36 T cells promote distinct transcriptional programs of cutaneous inflammatory disease in human skin structural cells
DeBerg, H. A.; Fahning, M. L.; Schlenker, J. D.; Schmitt, W. P.; Gratz, I. K.; Carlin, J. S.; Campbell, D. J.; Morawski, P. A.
10.1101/2024.07.31.606077 — immunology — Posted on 2024-08-31
37 Foundation model of neural activity predicts response to new stimulus types and anatomy
Wang, E. Y.; Fahey, P. G.; Ding, Z.; Papadopoulos, S.; Ponder, K.; Weis, M. A.; Chang, A.; Muhammad, T.; Patel, S.; Ding, Z.; Tran, D. T.; Fu, J.; Schneider-Mizell, C. M.; Reid, R. C.; Collman, F.; da Costa, N. M.; Franke, K.; Ecker, A. S.; Reimer, J.; Pitkow, X.; Sinz, F. H.; Tolias, A. S.
10.1101/2023.03.21.533548 — neuroscience — Posted on 2024-08-31
39 Mechanosensory Systems and Sensory Integration Mediate C. elegans Negative Gravitaxis
Ackley, C. R.; Washiashi, L.; Ziaei Kajbaf, N.; Krishnamurthy, R.; Sun, Z.; Duong, V.; Choe, K.; Lane, E.; Wood, C.; Smith, E.; Pellegrini, G.; Sherwin, M.; Joshi, P.; Rothman, J. H.
10.1101/2022.03.03.482913 — neuroscience — Posted on 2024-08-31
40 Remyelination protects neurons from DLK-mediated neurodegeneration
Duncan, G. J.; Ingram, S. D.; Emberley, K.; Hill, J.; Cordano, C.; Abdelhak, A.; McCane, M.; Jenks, J. E.; Jabassini, N.; Ananth, K.; Ferrara, S. J.; Stedelin, B.; Sivyer, B.; Aicher, S. A.; Watkins, T. A.; Mishra, A.; Nelson, J.; Green, A. J.; Emery, B.
10.1101/2023.09.30.560267 — neuroscience — Posted on 2024-08-31
41 Cortical tracking of postural sways during standing balance.
Legrand, T.; Mongold, S. J.; Muller, L.; Naeije, G.; Vander Ghinst, M.; Bourguignon, M.
10.1101/2023.12.08.570752 — neuroscience — Posted on 2024-08-31
43 Event boundaries drive norepinephrine release and distinctive neural representations of space in the rodent hippocampus
McKenzie, S.; Sommer, A. L.; Donaldson, T. N.; Pimentel, I.; Kakani, M.; Choi, I. J.; Newman, E. L.; English, D. F.
10.1101/2024.07.30.605900 — neuroscience — Posted on 2024-08-31
44 Amputation Triggers Long-Range Epidermal Permeability Changes in Evolutionarily Distant Regenerative Organisms
Dooling, K. E.; Kim, R. T.; Kim, E. M.; Chen, E.; Abouelela, A.; Tajer, B. J.; Lopez, N. J.; Paoli, J. C.; Powell, C. J.; Luong, A. G.; Wu, S. Y. C.; Thornton, K. N.; Singer, H. D.; Savage, A. M.; Bateman, J.; DiTommaso, T.; Payzin-Dogru, D.; Whited, J. L.
10.1101/2024.08.29.610385 — physiology — Posted on 2024-08-31
46 Transport of herbicides by PIN-FORMED auxin transporters
Schulz, L.; Ung, K. L.; Koutnik-Abele, S.; Stokes, D. L.; Pedersen, B. P.; Hammes, U.
10.1101/2024.08.29.610046 — biochemistry — Posted on 2024-08-31
47 Evolution of sex differences in cooperation: the role of trade-offs with dispersal
Capilla-Lasheras, P.; Bircher, N.; Brown, A.; Harrison, X.; Reed, T. E.; York, J.; Cram, D.; Rutz, C.; Walker, L.; Naguib, M.; Young, A.
10.1101/2023.09.13.557370 — evolutionary biology — Posted on 2024-08-31
49 eIF3 engages with 3'-UTR termini of highly translated mRNAs
Mestre-Fos, S.; Ferguson, L.; Trinidad, M. I.; Ingolia, N.; Cate, J. H. D.
10.1101/2023.11.11.566681 — molecular biology — Posted on 2024-08-31
51 Fes-deficient macrophages enhance CD8+ T cell priming and tumour control through increased proinflammatory cytokine production and localization
Laight, B. J.; Harper, D.; Dmytryk, N.; Zhang, S.; Garven, A.; Shi, C.; Nauman, R.; Kment, J.; Alotaibi, F.; Shapovalov, I.; Gao, Y.; Mewburn, J.; Vlasschaert, C.; LeBrun, D.; Tyryshkin, K.; Berman, D. M.; Simpson, A. L.; Graham, C.; Craig, A. W.; Basta, S.; Koti, M.; Greer, P. A.
10.1101/2024.02.27.581601 — immunology — Posted on 2024-08-31
52 Rapid synthesis and screening of natively paired antibodies against influenza hemagglutinin stem via oPool+ display
Ouyang, W. O.; Lv, H.; Liu, W.; Mou, Z.; Lei, R.; Pholcharee, T.; Wang, Y.; Dailey, K. E.; Gopal, A. B.; Choi, D.; Ardagh, M. R.; Talmage, L.; Rodriguez, L. A.; Dai, X.; Wu, N. C.
10.1101/2024.08.30.610421 — immunology — Posted on 2024-08-31
53 Computational Modeling shows Confirmation Bias during Formation and Revision of Self-Beliefs
Schröder, A.; Czekalla, N.; Mayer, A. V.; Zhang, L.; Stolz, D. S.; Korn, C. W.; Diekelmann, S.; Paulus, F. M.; Müller-Pinzler, L.; Krach, S.
10.1101/2024.08.30.610443 — neuroscience — Posted on 2024-08-31
58 Dopamine and temporal discounting: revisiting pharmacology and individual differences
Smith, E.; Theis, H.; van Eimeren, T.; Knauth, K.; Tuzsus, D.; Zhang, L.; Mathar, D.; Peters, J.
10.1101/2024.08.28.610170 — neuroscience — Posted on 2024-08-31
60 Direct binding of a fungal effector by the wheat RWT4 tandem kinase activates defense
Sung, Y.-C.; Li, Y.; Bernasconi, Z.; Baik, S.; Asuke, S.; Keller, B.; Fahima, T.; Coaker, G.
10.1101/2024.04.30.591956 — plant biology — Posted on 2024-08-31
61 Exploring transient states of PAmKate to enable improved cryogenic single-molecule imaging
Perez, D.; Dowlatshahi, D. P.; Azaldegui, C. A.; Ansell, T. B.; Dahlberg, P. D.; Moerner, W. E.
10.1101/2024.04.24.590965 — biophysics — Posted on 2024-08-31
63 StarSignDNA: Signature tracing for accurate representation of mutational processes
Bope, c. D.; Kalyanasundaram, S.; Rand, K. D.; Nakken, S.; Lingjaerde, O. C.; Hovig, E.
10.1101/2024.06.29.601345 — bioinformatics — Posted on 2024-08-31
64 ARTIC RSV amplicon sequencing reveals global RSV genotype dynamics.
Maloney, D. M.; Fernandes, G.; Jasim, S.; Williams, T.; Namugenyi, S.; Carr, M.; Meyer, J. R.; Sharma, A.; Marshal, L.; Nunley, B. E.; Xie, H.; Carvajal, M.; Kunerth, H. D.; Tanmoy, A.; O'Toole, A.; Weixler, A.; Lanter, K. R.; Gonzalez, G.; Sereewit, J.; Guevara, R.; Loose, M.; Fanning, P. M.; Benitez, D.; Fernandez, J. C.; Cardenas, P.; Hare, D.; Greninger, A.; Williams, T.; Nebbia, G.; Fries, A. C.; McClure, P.; Roychoudhury, P.; Wang, X.; Saha, S.; Dewar, R.; Templeton, K. E.; Rambaut, A.
10.1101/2024.08.23.609324 — genomics — Posted on 2024-08-31
66 DNA methylation insulates genic regions from CTCF loops near nuclear speckles
Roseman, S. A.; Siegenfeld, A. P.; Lee, C.; Lue, N. Z.; Waterbury, A. L.; Liau, B. B.
10.1101/2023.07.26.550645 — genomics — Posted on 2024-08-31
69 Experimental evolution of gene essentiality in bacteria
Bao, L.; Zhu, Z.; Ismail, A.; Zhu, B.; Anandan, V.; Whiteley, M.; Kitten, T.; Xu, P.
10.1101/2024.07.16.600122 — evolutionary biology — Posted on 2024-08-31
70 Abundance and distribution of ringed and bearded seals in the Chukchi Sea: a reference for future trends
Boveng, P. L.; Chernook, V. I.; Moreland, E. E.; Conn, P. B.; Trukhanova, I. S.; Cameron, M. F.; Christman, C. L.; Crawford, J. A.; Harwood, L.; Hou, B. X.; Koslovsky, S. M.; Lindsay, J. M.; Litovka, D. I.; London, J. M.; McClintock, B. T.; Platonov, N.; Quakenbush, L.; Richmond, E. L.; Vasiliev, A.; Von Duyke, A. L.; Willoughby, A.
10.1101/2024.08.27.608330 — ecology — Posted on 2024-08-31
71 MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features
Benkeder, S.; Dinh, S.-M.; Marchal, P.; De Gea, P.; Thoby-Brisson, M.; Hubert, V.; Hristovska, I.; Pitollat, G.; Combet, K.; Cardoit, L.; Pillot, B.; Leon, C.; Wiart, M.; Marthy, S.; Honnorat, J.; Pascual, O.; Comte, J.-C.
10.1101/2024.08.29.609024 — neuroscience — Posted on 2024-08-31
72 Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution
Hills, M. H.; Ma, L.; Fang, A.; Chiremba, T.; Malloy, S.; Scott, A. R.; Perera, A. G.; Yu, R.
10.1101/2024.02.22.581574 — neuroscience — Posted on 2024-08-31
73 Dataset factors associated with age-related changes in brain structure and function in neurodevelopmental conditions
Vandewouw, M. M.; Ye, Y. J.; Crosbie, J.; Schachar, R. J.; Iaboni, A.; Georgiades, S.; Nicolson, R.; Kelley, E.; Ayub, M.; Jones, J.; Arnold, P. D.; Taylor, M. J.; Lerch, J. P.; Anagnostou, E.; Kushki, A.
10.1101/2024.05.09.591294 — neuroscience — Posted on 2024-08-31
74 Context-dependent neural preparation for information relevance vs. probability
Penalver, J. M. G.; Gonzalez-Garcia, C.; Palenciano, A. F.; Lopez-Garcia, D.; Ruz, M.
10.1101/2024.05.20.594985 — neuroscience — Posted on 2024-08-31
79 Specific redox and iron homeostasis responses in the root tip of Arabidopsis upon zinc excess
Thiebaut, N.; Richtmann, L.; Sarthou, M. C. M.; Persson, D. P.; Ranjan, A.; Schloesser, M.; Boutet, S.; Rezende, L.; Clemens, S.; Verbruggen, N.; Hanikenne, M.
10.1101/2024.08.29.610234 — plant biology — Posted on 2024-08-31
80 Fc immunoreceptors promote autophagy to regulate monocyte functions
Saveanu, L.; Nugue, M.; D'Allemagne, M.; Koumantou, D.; Vetillard, M.; Cragg, M.; Bourdely, P.; Lotersztajn, S.
10.1101/2024.08.29.610296 — cell biology — Posted on 2024-08-31
81 Chromatin Remodelling in Damaged Intestinal Crypts Orchestrates Redundant TGFβ and Hippo Signalling to Drive Regeneration
Fink, M.; Njah, K.; Pagtel, S.; Cook, D.; Man, V.; Ruso, F.; Rajan, A.; Narimatsu, M.; Obersterescu, A.; Pye, M.; Trcka, D.; Chan, K.; Ayyaz, A.; Wrana, J.
10.1101/2024.08.30.610472 — molecular biology — Posted on 2024-08-30
82 Spatiotemporal Single-Cell Roadmap of Human Skin Wound Healing
Liu, Z.; Li, D.; Bian, X.; Luo, L.; Bjorklund, A.; Li, L.; Zhang, L.; Chen, Y.; Guo, L.; Gao, J.; Cao, C.; Wang, J.; He, W.; Xiao, Y.; Zhu, L.; Annusver, K.; Gopee, N. H.; Bennett, C. L.; Kasper, M.; Haniffa, M.; Sommar, P.; Xu Landen, N.
10.1101/2024.08.30.609923 — cell biology — Posted on 2024-08-30
91 Mast cells are not essential for pubertal mammary gland branching.
Kapoor, S.; Marsden, J.; Munz, C. M.; Carvalho, C.; Magalhaes Pinto, M.; Malengier-Devlies, B.; Becker, S.; Seuzaret, G.; Patatsos, K.; Akyol, R.; DALOD, M.; Pedersen, A. B.; Wilson, G. J.; Gentek, R.
10.1101/2024.08.30.610382 — developmental biology — Posted on 2024-08-30
95 SARS-CoV-2 Delta variant induces severe damages in the nasal cavity from the first day post-infection in the Syrian hamster model.
Fusade-Boyer, M.; Gambino, A.; Merle-Nguyen, L.; Saint-Albin, A.; Ando-Grard, O.; Boujedli, Y.; Huet, H.; Ar Gouilh, M.; Martin-Latil, S.; Klonjkowski, B.; Meunier, N.; Le Poder, S.
10.1101/2024.08.30.610497 — microbiology — Posted on 2024-08-30
96 Epigenetic control of commensal induced Th2 Responses and Intestinal immunopathology
Sangani, K. A.; Parker, M. E.; Anderson, H. D.; Chen, L.; Pandey, S. P.; Pierre, J. F.; Meisel, M.; Riesenfeld, S. J.; Hinterleitner, R.; Jabri, B.
10.1101/2024.08.30.610485 — immunology — Posted on 2024-08-30
97 Rapid synthesis and screening of natively paired antibodies against influenza hemagglutinin stem via oPool+ display
Ouyang, W. O.; Lv, H.; Liu, W.; Mou, Z.; Lei, R.; Pholcharee, T.; Wang, Y.; Dailey, K. E.; Gopal, A. B.; Choi, D.; Ardagh, M. R.; Talmage, L.; Rodriguez, L. A.; Dai, X.; Wu, N. C.
10.1101/2024.08.30.610421 — immunology — Posted on 2024-08-30
98 Computational Modeling shows Confirmation Bias during Formation and Revision of Self-Beliefs
Schroder, A.; Czekalla, N.; Mayer, A. V.; Zhang, L.; Stolz, D. S.; Korn, C. W.; Diekelmann, S.; Paulus, F. M.; Muller-Pinzler, L.; Krach, S.
10.1101/2024.08.30.610443 — neuroscience — Posted on 2024-08-30
100 Human deep sleep facilitates faster cerebrospinal fluid dynamics linked to brain oscillations for sleep homeostasis and memory
Uji, M.; Li, X.; Saotome, A.; Katsumata, R.; Waggoner, R. A.; Suzuki, C.; Ueno, K.; Aritake, S.; Tamaki, M.
10.1101/2024.08.30.610454 — neuroscience — Posted on 2024-08-30
102 Gaze biases can reflect task-specific spatial memorization strategies
Chota, S.; Arora, K.; Kenemans, L.; Gayet, S.; Van der Stigchel, S.
10.1101/2024.08.30.610231 — neuroscience — Posted on 2024-08-30
104 Plasma membrane H+-ATPase activation increases global transcript levels and promotes the shoot growth of light-grown Arabidopsis seedlings.
Kinoshita, S. N.; Taki, K.; Okamoto, F.; Nomoto, M. N.; Takahashi, K.; Hayashi, Y.; Ohkanda, J.; Tada, Y.; Finkemeier, I.; Kinoshita, T.
10.1101/2024.08.30.610460 — plant biology — Posted on 2024-08-30
106 A wheat tandem kinase sensor activates an NLR helper to trigger immunity
Chen, R.; Chen, J.; Outram, M. A.; Powell, O. R.; Arndell, T.; Gajendiran, K.; Wang, Y. L.; Ayliffe, M. A.; Blundell, C.; Figueroa, M.; Sperschneider, J.; Vanhercke, T.; Tang, D.; Xu, Y.; Zhong, G.; Gardener, C.; Yu, G.; Gourdoupis, S.; Jaremko, L.; Matny, O.; Steffenson, B. J.; Boshoff, W. H. P.; Meyer, W. B.; Arold, S. T.; Dodds, P. N.; Wulff, B. B. H.
10.1101/2024.08.30.610287 — plant biology — Posted on 2024-08-30
108 Two-Photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure
Musimbi, Z. D.; Kundik, A.; Krucken, J.; Hauser, A. E.; Rausch, S.; Seeberger, P. H.; Niesner, R.; Leben, R.; Hartmann, S.
10.1101/2024.08.30.610452 — biophysics — Posted on 2024-08-30
109 Active foam dynamics of tissue spheroid fusion
Ongenae, S.; Svitina, H.; Belpaire, T. E. R.; Vangheel, J.; Martens, T.; Vanden Berghe, P.; Papantoniou, I.; Smeets, B.
10.1101/2024.08.30.610303 — biophysics — Posted on 2024-08-30
111 Fluralaner treatment of chickens kills the southern house mosquito, Culex quinquefasciatus
Knape, K.; Tian, Y.; Durden, C.; Adams, D. R.; Garza, M.; Carey, J. B.; Hamer, S. A.; Hamer, G. L.
10.1101/2024.08.30.610151 — biochemistry — Posted on 2024-08-30
115 ABC-seq expands small RNAs content with randomized adapter pools operation
Yu, H.; Ye, M.; Guo, Y.; Sun, Y.; Cao, K.; Zhang, D.; Chen, F.; Zhao, Y.
10.1101/2024.08.30.610480 — genomics — Posted on 2024-08-30
120 Hungry catfish - effect of prey availability on movement dynamics of a top predator
Riha, M.; Rabaneda Bueno, R.; Vejrik, L.; Jaric, I.; Prchalova, M.; Smejkal, M.; Cech, M.; Drastik, V.; Blabolil, P.; Holubova, M.; Juza, T.; Gjelland, K.; Sajdlova, Z.; Kocvara, L.; Tuser, M.; Peterka, J.
10.1101/2024.08.30.610378 — ecology — Posted on 2024-08-30
122 Plasma membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ankh) mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing
James, E. N.; Teh, M.-T.; Li, Y.; Wagner-bock, C.; Al-Khateeb, Z. F.; Karen-Ng, L. P.; Roberts, T.; Synchyshyn, L.; Lewis, A.; O'Loghlen, A.; Silver, A.; Michael-Titus, A. T.; Bennett, M.; Bundy, J. G.; Mycielska, M. E.; Parkinson, E. K.
10.1101/2024.08.30.609895 — cell biology — Posted on 2024-08-30
123 LAPTM4B Alleviates Pulmonary Fibrosis by Enhancing NEDD4L-Mediated TGF-beta Signaling Suppression
Xu, K.; Pan, X.; Lian, H.; Wang, Y.; Wan, R.; Li, Z.; Pan, X.; Li, Y.; Yang, J.; Rosas, I.; Wang, L.; Yu, G.
10.1101/2024.08.30.610429 — cell biology — Posted on 2024-08-30
126 Immunological memory in a teleost fish: common carp IgM+ B cells differentiate into memory and plasma cells
Chan, J. T. H.; Picard-Sanchez, A.; Dedic, N.; Majstorovic, J.; Rebl, A.; Holzer, A. S.; Korytar, T.
10.1101/2024.08.30.610468 — immunology — Posted on 2024-08-30
128 Neural contrast sensitivity is not affected by myopic blur
Domdei, N.; Mueller, J.; Renner, L.; Ameln, J.; Breher, K.; Harmening, W. M.; Wahl, S.
10.1101/2024.08.30.610275 — neuroscience — Posted on 2024-08-30
131 A wheat tandem kinase and NLR pair confers resistance to multiple fungal pathogens
Lu, P.; Zhang, G.; Li, J.; Gong, Z.; Wang, G.; Dong, L.; Zhang, H.; Guo, G.; Su, M.; Wang, Y.; Zhu, K.; Wu, Q.; Chen, Y.; Li, M.; Huang, B.; Li, B.; Li, W.; Dong, L.; Hou, Y.; Cui, X.; Fu, H.; Qiu, D.; Yuan, C.; Li, H.; Zhou, J.; Han, G. z.; Chen, Y.-h.; Liu, Z.
10.1101/2024.08.30.610185 — plant biology — Posted on 2024-08-30
132 High-speed Intracellular Temperature Mapping Reveals the Existence of Non-Conductive Dissipation of Energy by Heating
Takarada, M.; Shirakashi, R.; Takinoue, M.; Ishida, M.; Morita, M.; Noji, H.; Tabata, K. V.; Funatsu, T.; Okabe, K.
10.1101/2024.08.29.610413 — biophysics — Posted on 2024-08-30
134 Enhancement of network architecture alignment in comparative single-cell studies
Schaechter, C.; Treppner, M.; Hackenberg, M.; Raum, H.; Boedecker, J.; Binder, H.
10.1101/2024.08.30.608255 — bioinformatics — Posted on 2024-08-30
137 Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic Schistosoma mansoni
Berger, D. J.; Park, S.-K.; Crellen, T.; Vianney, T. J.; Kabatereine, N. B.; Cotton, J. A.; Sanya, R.; Elliot, A.; Tukahebwa, E. M.; Adriko, M.; Standley, C. J.; Gouvras, A.; Kinunghi, S.; Haas, H.; Rabone, M.; Emery, A.; Lamberton, P. H. L.; Webster, B. L.; Allan, F.; Buddenborg, S.; Berriman, M.; Marchant, J. S.; Doyle, S. R.; Webster, J. P.
10.1101/2024.08.29.610291 — genomics — Posted on 2024-08-30
141 Effect of high-intensity anaerobic exercise on electrocortical activity in athletes and non-athletes
Costa, E. P.; Gongora, M.; Bittencourt, J.; Marinho, V.; Cagy, M.; Teixeira, S.; Nicoliche, E.; Fernandes, I.; Fagundes, D.; Machado, C.; Dias, J.; Vicente, R.; Ribeiro, P.; Gupta, D.; Velasques, B.; Budde, H.
10.1101/2024.08.29.610409 — neuroscience — Posted on 2024-08-30
143 A microendovascular system can record precise neural signals from cortical and deep vessels with minimal invasiveness
Iwata, T.; Nakamura, H.; Uemura, T.; Araki, T.; Matsumura, T.; Abe, T.; Nezu, T.; Takagaki, M.; Ozaki, T.; Miura, S.; Fukuma, R.; John, S. E.; Grayden, D. B.; Kishima, H.; Sekitani, T.; Yanagisawa, T.
10.1101/2024.08.29.610418 — neuroscience — Posted on 2024-08-30
145 Numerosity adaptation suppresses early visual responses
Zhang, L.; Hendrikx, E.; Wang, Y.; Gayet, S.; Dumoulin, S. O.; Harvey, B. M.
10.1101/2024.08.29.610311 — neuroscience — Posted on 2024-08-30
146 Analysis and control of untemplated DNA polymerase activity for guided synthesis of kilobase-scale DNA sequences
Castle, S. D.; Woolfson, A.; Linshiz, G.; Riley, B. T.; Samuel, I. D. W.; Holliger, P.; Oldfield, L.; Hessel, A.; Gorochowski, T. E.
10.1101/2024.08.29.610422 — synthetic biology — Posted on 2024-08-30
150 Highly dynamic mechanical transitions in embryonic cell populations during Drosophila gastrulation
Gomez, J. M.; Bevilacqua, C.; Thayambath, A.; Leptin, M.; Belmonte, J.; Prevedel, R.
10.1101/2024.08.29.610383 — biophysics — Posted on 2024-08-30
153 Detailed delineation of the fetal brain in diffusion MRI via multi-task learning
Karimi, D.; Calixto Nunez, C.; Snoussi, H.; Cortes-Albornoz, M. C.; Velasco-Annis, C.; Rollins, C.; Jaimes, C.; Gholipour, A.; Warfield, S. K.
10.1101/2024.08.29.609697 — bioengineering — Posted on 2024-08-30
154 Isolation, identification, and characterisation of the malachite green detoxifying bacterial strain Bacillus pacificus ROC1 and the azoreductase AzrC
Bibi, S.; Breeze, C. W.; Jadoon, V.; Fareed, A.; Syed, A.; Frkic, R. L.; Zaffar, H.; Ali, M.; Zeb, I. W.; Jackson, C. J.; Naqvi, T. A.
10.1101/2024.08.29.610417 — biochemistry — Posted on 2024-08-30
157 Posterior specification of multi-lineage axial assembloids from human pluripotent stem cells.
Kee, N.; Leboeuf, M.; Gomez, S.; Petipre, C.; Mei, I.; Benlefki, S.; Hagey, D. W.; Dias, J.; Lallemend, F.; EL Andaloussi, S.; Ericson, J.; Hedlund, E.
10.1101/2024.08.29.610410 — cell biology — Posted on 2024-08-30
159 Structural and functional insights into Cdc45 recruitment by Sld7-Sld3 for CMG complex formation
Li, H.; Ishizaki, I.; Kato, K.; Sun, X.; Muramatsu, S.; Itou, H.; Ose, T.; Araki, H.; Yao, M.
10.1101/2024.08.29.610416 — molecular biology — Posted on 2024-08-30
160 Established Pseudomonas syringae pv. tomato infection disrupts immigration of leaf surface bacteria to the apoplast
Cowles, K. N.; Iyer, A. S.; McConnell, I.; Guillemette, E. G.; Nellore, D.; Zaacks, S. C.; Barak, J. D.
10.1101/2024.08.29.610363 — microbiology — Posted on 2024-08-30
166 Integrated Dual-Channel Retrograde Signaling Directs Stress Responses by Degrading the HAT1/TPL/IMPalpha-9 Suppressor Complex and Activating CAMTA3
Zeng, L.; Guo, J.; Palayam, M.; Rodriguez, C.; Gomez Mendez, M. F.; Wang, Y.; Ven, W. v. d.; Pruneda-Paz, J.; Shabek, N.; Dehesh, K.
10.1101/2024.08.29.610327 — plant biology — Posted on 2024-08-30
167 Adipose tissue protein kinase D (PKD): regulation of signalling networks and its sex-dependent effects on metabolism
Renton, M. C.; Humphrey, S. J.; Connor, T.; Martin, S. D.; Kremerer, K.; Fernando, H.; Shaw, C. S.; James, D. E.; Howlett, K. F.; McGee, S. L.
10.1101/2024.08.29.610294 — physiology — Posted on 2024-08-30
168 Role of AMPK in Atrial Metabolic Homeostasis and Substrate Preference
Toksoy, Z.; Ma, Y.; Goedeke, L.; Li, W. V.; Hu, X.; Wu, X.; Cacheux, M.; Liu, Y.; Akar, F. G.; Shulman, G. I.; Young, L. H.
10.1101/2024.08.29.608789 — physiology — Posted on 2024-08-30
169 Six months of physical inactivity is insufficient to cause chronic kidney disease in C57BL/6J mice
Opurum, P. C.; Decker, S. T.; Stuart, D.; Peterlin, A. D.; Paula, V. L.; Siripoksup, P.; Drummond, M. J.; Sanchez, A.; Ramkumar, N.; Funai, K.
10.1101/2024.08.29.610415 — physiology — Posted on 2024-08-30
170 Multi-omics analysis of virus-permissive versus hostile cellular states reveals protein networks controlling virus infection
Chen, H.; Charles, P. D.; Gu, Q.; Liberatori, S.; Robertson, D. L.; Palmarini, M.; Wilson, S. J.; Mohammed, S.; Castello, A.
10.1101/2024.08.29.610331 — pathology — Posted on 2024-08-30
172 Design, Synthesis, and Efficacy of Novel Trojan Horse Compounds Targeting Metabolic Vulnerabilities in Prostate Cancer
Edgerton, L. B.; Hayball, E. F.; O'Connell, F.; Ward, M. P.; O'Toole, S.; Martin, C. M.; Selemidis, S.; Brooks, R. D.; Tewari, P.; Brooks, D. A.; O'Leary, J. J.
10.1101/2024.08.29.610353 — cancer biology — Posted on 2024-08-30
173 Multimodal Spatial Proteomic Profiling in Acute Myeloid Leukemia
Ly, C.; Veletic, I.; Pacheco, C.; Dasdemir, E.; Jelloul, F. Z.; Ferri-Borgogno, S.; Basi, A. V.; Gomez, J. A.; Root, J. L.; Reville, P. K.; Sharma, P.; Basu, S.; Quesada, A. E.; Bueso-Ramos, C.; Manshouri, T.; Garcia, M. B.; Burks, J. K.; Abbas, H.
10.1101/2024.08.30.610347 — cancer biology — Posted on 2024-08-30
176 paraCell: A novel software tool for the interactive analysis and visualization of standard and dual host-parasite single cell RNA-Seq data
Agboraw, E.; Haese-Hill, W.; Hentzschel, F.; Briggs, E. M.; Aghabi, D.; Heawood, A.; Harding, C. R.; Schiels, B.; Crouch, K. R.; Somma, D.; Otto, T. D.
10.1101/2024.08.29.610375 — bioinformatics — Posted on 2024-08-30
177 Self-Assembled Generation of Multi-zonal Liver Organoids from Human Pluripotent Stem Cells
Al-Reza, H.; Santangelo, C.; Al-Reza, A.; Iwasawa, K.; Sekiya, S.; Glaser, K.; Bondoc, A.; Merola, J.; Takebe, T.
10.1101/2024.08.30.610426 — bioengineering — Posted on 2024-08-30
179 De novo design of Ras isoform selective binders
Zhang, J. Z.; Li, X.; Liu, C.; Jiang, H.; Wu, K.; Baker, D.
10.1101/2024.08.29.610300 — bioengineering — Posted on 2024-08-30
181 Extracellular Vesicle-Mediated Delivery of HIF1a Reprograms Macrophages for resolutive response in Sepsis
Lee, Y.; Goo, J.; Cho, S.; Kim, S. A.; Nam, G.-H.; Kim, I.; Park, J.-W.; Jeong, C.; Kim, I.-S.
10.1101/2024.08.29.608900 — bioengineering — Posted on 2024-08-30
182 Transport of herbicides by PIN-FORMED auxin transporters
Schulz, L.; Ung, K. L.; Koutnik-Abele, S.; Stokes, D. L.; Pedersen, B. P.; Hammes, U.
10.1101/2024.08.29.610046 — biochemistry — Posted on 2024-08-30
183 Computational design of serine hydrolases
Lauko, A.; Pellock, S. J.; Anischanka, I.; Sumida, K. H.; Juergens, D.; Ahern, W.; Shida, A.; Hunt, A.; Kalvet, I.; Norn, C.; Humphreys, I. R.; Jamieson, C. S.; Kang, A.; Brackenbrough, E.; Sankaran, B.; Houk, K. N.; Baker, D.
10.1101/2024.08.29.610411 — biochemistry — Posted on 2024-08-30
186 Atlas-scale Single-cell DNA Methylation Profiling with sciMETv3
Nichols, R. V.; Rylaarsdam, L.; O'Connell, B. L.; Shipony, Z.; Iremadze, N.; Acharya, S. N.; Adey, A.
10.1101/2024.08.29.610369 — genetics — Posted on 2024-08-30
189 Do fungi look like macroparasites? Quantifying the patterns and mechanisms of aggregation for host-fungal parasite relationships
Schrock, S. A.; Walsman, J. C.; DeMarchi, J.; LeSage, E. H.; Ohmer, M. E. B.; Rollins-Smith, L. A.; Briggs, C. J.; Richards-Zawacki, C. L.; Woodhams, D. C.; Knapp, R. A. R.; Smith, T. C.; Haddad, C. F. B.; Becker, C. G.; Johnson, P. T. J.; Wilber, M. Q.
10.1101/2024.08.29.609018 — ecology — Posted on 2024-08-30
190 Coordinated Tbx3 / Tbx5 transcriptional control of the adult ventricular conduction system
Burnicka-Turek, O.; Trampel, K. A.; Laforest, B.; Broman, M. T.; Khan, Z.; Rytkin, E.; Li, B.; Schaffer, E.; Gadek, M.; Shen, K. M.; Efimov, I. R.; Moskowitz, I. P.
10.1101/2024.08.29.610377 — developmental biology — Posted on 2024-08-30
194 Rapid visual engagement in neural processing of detailed touch interactions
Smit, S.; Ramirez-Haro, A.; Quek, G. L.; Varlet, M.; Moerel, D.; Grootswagers, T.
10.1101/2024.08.29.610402 — neuroscience — Posted on 2024-08-30
196 Epigenomic anomalies in induced pluripotent stem cells from Alzheimer disease cases
Flamier, A.; Katbe, A.; Serhani, D.; Hamam, R.; Hogan, R.; Tavares, E.; Heon, E.; Hanna, R.; Bernier, G.
10.1101/2024.08.29.610372 — neuroscience — Posted on 2024-08-30
199 Multimodal brain imaging of insomnia, depression and anxiety symptoms: transdiagnostic commonalities and differences
de Lange, S. C.; Tissink, E.; Bresser, T.; Savage, J. E.; Posthuma, D.; van den Heuvel, M. P.; van Someren, E. J.
10.1101/2024.08.30.610439 — neuroscience — Posted on 2024-08-30
200 The Balanced Mind and its Intrinsic Neural Timescales in Advanced Meditators
Malipeddi, S.; Sasidharan, A.; Venugopal, R.; Ventura, B.; Bauer, C. C.; P.N., R.; Mehrotra, S.; John, J. P.; Kutty, B. M.; Northoff, G.
10.1101/2024.08.29.609126 — neuroscience — Posted on 2024-08-30
202 Transcription factors SlMYB41, SlMYB92 and SlWRKY71 regulate gene expression in tomato exodermis
Jo, L.; Buti, S.; Artur, M. S.; Kluck, R. M. C.; Canto Pastor, A.; Brady, S.; Kajala, K.
10.1101/2024.08.29.610307 — plant biology — Posted on 2024-08-30
204 Hawkmoth pheromone transduction involves G protein-dependent phospholipase Cβ signaling
Schneider, A. C.; Schroeder, K.; Chang, Y.; Nolte, A.; Gawalek, P.; Stengl, M.
10.1101/2024.08.29.610295 — physiology — Posted on 2024-08-30
205 The gut microbiota is a determinant of sexual dimorphism in ALS-linked TDP43 mice
Beraldi, E. J.; Lee, S.; Jiang, Y.; Rea, I. M.; Phull, R.; Keenan, C. M.; Stephens, M.; Bardhi, M.; Bankole, O.; Pfeffer, G.; Biernaskie, J.; McCoy, K. D.; Elinav, E.; Sharkey, K. A.; Nguyen, M. D.
10.1101/2024.08.29.610355 — physiology — Posted on 2024-08-30
208 Single-Molecule Studies of Cognate and Near-Cognate Elongation in an in vitro Eukaryotic Translation System
Fritsch, C.; Bhattacharya, A.; Ng, M. Y.; Li, H.; Nelson, P. C.; Cooperman, B. S.; Goldman, Y. E.
10.1101/2024.08.29.609187 — biophysics — Posted on 2024-08-30
212 Sex and morph variation in activity from early ontogeny to maturity in ruffs (Calidris pugnax)
Rohr-Bender, V. A.; Kupan, K.; Lopez-Nava, G.; Forstmeier, W.; Hertel, A.; Razumov, V.; Martin, K.; Kempenaers, B.; Kuepper, C.
10.1101/2024.08.30.610446 — animal behavior and cognition — Posted on 2024-08-30
215 Centromeric transposable elements and epigenetic status drive karyotypic variation in the eastern hoolock gibbon
Hartley, G. A.; Okhovat, M.; Hoyt, S. J.; Fuller, E.; Pauloski, N.; Alexandre, N.; Alexandrov, I. A.; Drennan, R. S.; Dubocanin, D.; Gilbert, D. M.; Mao, Y.; McCann, C.; Neph, S.; Ryabov, F.; Sasaki, T.; Storer, J. M.; Svendsen, D.; Troy, W.; Wells, J.; Core, L.; Stergachis, A.; Carbone, L.; O'Neill, R. J.
10.1101/2024.08.29.610280 — genomics — Posted on 2024-08-30
216 Reliability of canopy photography for forest ecology and biodiversity studies
von Meijenfeldt, A.; Chianucci, F.; Rigo, F.; Ottenburghs, J.; Hilpold, A.; Mina, M.
10.1101/2024.08.29.610276 — ecology — Posted on 2024-08-30
217 A-Islands: A plant dataset for biodiversity research and species monitoring on Australian islands
Schrader, J.; Coleman, D.; Abbott, I.; Bryant, S.; Buckley, R.; Crayn, D.; Gallagher, R. V.; Harris, S.; Heatwole, H.; Jackes, B.; Kreft, H.; Mills, K.; Kirkpatrick, J.; Latz, P. K.; Neldner, J.; Sattler, C.; Visoiu, M.; Wenk, E. H.; Woinarski, J. C. Z.; Wright, I. J.; Zorn, I.; Westoby, M.
10.1101/2024.08.29.609992 — ecology — Posted on 2024-08-30
219 Phospho-regulated tuning of viscoelastic properties balances centrosome growth and strength
Amato, M.; Hwang, J. H.; Rios, M. U.; Familiari, N. E.; Rosen, M. K.; Woodruff, J. B.
10.1101/2024.08.29.610374 — cell biology — Posted on 2024-08-30
221 The lincRNA Pantr1 is a FOXG1 target gene conferring site-specific chromatin binding of FOXG1
Gather, F.; Rauleac, T.; Akol, I.; Arumugam, G.; Fullio, C. L.; Mueller, T.; Kleidonas, D.; Fischer, A.; Vlachos, A.; Backofen, R.; Vogel, T.
10.1101/2024.08.29.610239 — neuroscience — Posted on 2024-08-30
222 Stable White Matter Structure in the First Three Years after Psychosis Onset
Van Dyken, P. C.; Yang, K.; Faria, A. V.; Sawa, A.; MacKinley, M.; Khan, A. R.; Palaniyappan, L.
10.1101/2024.08.29.610312 — neuroscience — Posted on 2024-08-30
223 Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome
Verboven, A. H. A.; Puvogel, S.; Kolsters, N.; Latour, B.; Linda, K.; Lewerissa, E. I.; Mijdam, R.; Dyke, E.; Duineveld, D.; Zoodsma, M.; Claassen, W. J. J.; Oudakker, A.; Schoenmaker, C.; Koolen, D. A.; de Vries, B. B. A.; 't Hoen, P.-B. A. C.; Kasri, N. N.
10.1101/2024.08.29.610281 — neuroscience — Posted on 2024-08-30
224 Emergent metabolic interactions in resistance to Clostridioides difficile invasion
Ambat, A.; van den Berg, N. I.; Zorrilla, F.; Menon, S.; Maji, A.; Basile, A.; Ghimire, S.; Kalmar, L.; Patil, K. R.; Scaria, J.
10.1101/2024.08.29.610284 — systems biology — Posted on 2024-08-30
226 Guard-cell phytosterol homeostasis is critical for proper stomatal development
Yen, C.-C.; Hsu, Y.-W.; Leu, K.-C.; Chen, S.-S.; Chen, T.-Y.; Juan, C.-T.; Kuan, C.; Shaw, J.-F.; Ho, C.-M. K.; Jauh, G.-Y.
10.1101/2024.08.29.610202 — plant biology — Posted on 2024-08-30
229 A multi-omics analysis of Arabidopsis thaliana root tips under Cd exposure: A role of HY5 in limiting accumulation
Richtmann, L.; Thiebaut, N.; Ranjan, A.; Sarthou, M.; Boutet, S.; Hanikenne, M.; Clemens, S.; Verbruggen, N.
10.1101/2024.08.29.609871 — plant biology — Posted on 2024-08-30
237 Bone mechano-response is driven by locomotion transitions during vertebrate evolution
Shimochi, S.; Brunet, C.; Fontcuberta-Rigo, M.; Hrovat, K.; Puigbo, P.; Nakamura, M.
10.1101/2024.08.29.610233 — evolutionary biology — Posted on 2024-08-30
238 Evaluation of a Deep Learning Based Approach to Computational Label Free Cell Viability Quantification
Reno, A. H.; Tang, J.; Sudbeck, M.; Custodio, P. F.; Baldus, B.; McLaughlin, E.; Peng, F.; Xiao, H.
10.1101/2024.08.29.610252 — cell biology — Posted on 2024-08-30
239 IL-23 tunes inflammatory functions of human mucosal-associated invariant T (MAIT) cells
Camard, L.; Stephen, T.; Yahia-Cherbal, H.; Guillemot, V.; Mella, S.; Baillet, V.; Lopez-Maestre, H.; Capocefalo, D.; Cantini, L.; Leloup, C.; Marsande, J.; Sienes Bailo, J.; Dangien, A.; Pietrosemoli, N.; Hasan, M.; Wang, H.; Eckle, S. B. G.; Fourie, A. M.; Greving, C.; Shaikh, B. J.; Parker, R.; Cua, D. J.; Bianchi, E.; Rogge, L.
10.1101/2024.08.29.609178 — immunology — Posted on 2024-08-30
240 Regulatory architecture of disease resistance in maize revealed by multi-omic systems genetics
Clark, N. M.; Song, G.; Kabahuma, M. K.; Kolkman, J. M.; Christensen, S. A.; Montes-Serey, C.; Malik, S.; Nelson, R. J.; Walley, J. W.
10.1101/2024.08.29.610401 — plant biology — Posted on 2024-08-30
243 Neural Prioritisation of Past Solutions Supports Generalisation
Hall-McMaster, S.; Tomov, M. S.; Gershman, S. J.; Schuck, N. W.
10.1101/2024.06.10.598294 — neuroscience — Posted on 2024-08-30
251 Genome-wide methylation profiling of cell-free DNA in maternal plasma using Methylated DNA Sequencing (MeD-seq)
van Vliet, M. M.; Boers, R.; Boers, J. B.; Schaffers, O. J. M.; van der Meeren, L. E.; Steegers-Theunissen, R. P. M.; Gribnau, J.; Schoenmakers, S.
10.1101/2024.08.29.610227 — genomics — Posted on 2024-08-30
253 Genome concentration limits cell growth and modulates proteome composition in Escherichia coli
Makela, J.; Papagiannakis, A.; Lin, W.-H.; Lanz, M. C.; Glenn, S.; Swaffer, M.; Marinov, G. K.; Skotheim, J. M.; Jacobs-Wagner, C.
10.1101/2024.02.26.582181 — cell biology — Posted on 2024-08-30
254 Expression of IL-1R2 by Tfr prevents their IL-1-dependent proliferation and the exacerbation of allergy
Engeroff, P.; Belbezier, A.; Vaineau, R.; Fourcade, G.; Lujan, H. D.; Bellier, B.; Graff-Dubois, S.; Klatzmann, D.
10.1101/2024.08.29.610028 — immunology — Posted on 2024-08-30
255 Maternal humoral factors modulate offspring gut immune homeostasis to mitigate diabetes development
Strachan, E.; Pessoa-Soares, L.; Ju, T.; Schcolnik-Cabrera, A.; Wang, H.; Akbari, M.; Basso, P. J.; Winer, D. A.; Huang, C.; Julien, O.; Willing, B. P.; Clemente-Casares, X.; Tsai, S.
10.1101/2024.08.28.604371 — immunology — Posted on 2024-08-30
256 Brain Charts for the Rhesus Macaque Lifespan
Alldritt, S.; Ramirez, J. S. B.; Vos de Wael, R.; Bethlehem, R.; Seidlitz, J.; Wang, Z.; Nenning, K.-H.; Esper, N. B.; Smallwood, J.; Franco, A. R.; Byeon, K.; Alexander-Bloch, A.; Messinger, A.; Chen, A.; Thiele, A.; Weiss, A. R.; Shmuel, A.; Fox, A.; Tusche, A.; Brambrink, A. M.; Falchier, A.; Hiba, B.; Jarraya, B.; Jung, B.; Butler, B.; Russ, B. E.; Howell, B. R.; Drzewiecki, C. M.; Guedj, C.; Schwiedrzik, C. M.; Amiez, C.; Wilson, C. R. E.; Klink, C.; Kroenke, C.; Constantinidis, C.; Garin, C. M.; Poirier, C.; Gale, D. J.; Leopold, D. A.; Rudko, D. A.; Amaral, D. G.; Tsao, D.; Cook, D. J.;
10.1101/2024.08.28.610193 — neuroscience — Posted on 2024-08-30
257 Targeting Norepinephrine Neurons of the Locus Coeruleus: A Comparison of Model Systems and Strategies
Wissing, C.; Eschholz, L. S.; Maheu, M.; Sauter, K.; Morellini, F.; Wiegert, J. S.; Dieter, A.
10.1101/2022.01.22.477348 — neuroscience — Posted on 2024-08-30
259 5UTR translational inhibition of neuroblastoma dependency factors using the CR-1-31-B rocaglate
Nunes, C.; Bekaert, S.-L.; Parsa, S.; Nelen, I.; Martens, F.; De Stanchina, E.; Sanders, E.; Hilgert, E.; T'sas, S.; Zhao, P.; De Vloed, F.; Eggermont, A.; Goossens, S.; Sablina, A.; Depestel, L.; Wendel, H. G.; Durinck, K.
10.1101/2024.08.29.610236 — cancer biology — Posted on 2024-08-30
260 Transglutaminase 2 function in glioblastoma tumor efferocytosis
Lui, M.; Sevinc, F.; Elgafarawi, M.; Munoz, D. G.; Keillor, J. W.; Sinclair, J.; Catana, D.; Woulfe, J.; Lorimer, I. A.
10.1101/2024.08.29.610293 — cancer biology — Posted on 2024-08-30
261 USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization
Biber, P.; Carminati, A.; Girard, C. A.; Mohager, W.; Ohanna, M.; Lecacheur, M.; Bouvet, O.; Audebert, S.; Khaled, M.; Tartare-Deckert, S.; Deckert, M.
10.1101/2024.08.29.610314 — cancer biology — Posted on 2024-08-30
263 Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer
Mahat, D. B.; Kumra, H.; Castro, S. A.; Metcalf, E.; Nguyen, K.; Morisue, R.; Ho, W. W.; Chen, I.; Sullivan, B.; Yim, L. K.; Singh, A.; Fu, J.; Waterton, S. K.; Cheng, Y.-C.; Roberge, S.; Moiso, E.; Chauhan, V. P.; Moura Silva, H.; Spranger, S.; Jain, R. K.; Sharp, P. A.
10.1101/2024.08.28.609802 — cancer biology — Posted on 2024-08-30
264 Caveolin assemblies displace one bilayer leaflet to organize and bend membranes
Doktorova, M.; Daum, S.; Ebenhan, J.; Neudorf, S.; Han, B.; Sharma, S.; Kasson, P.; Levental, K.; Bacia, K.; Kenworthy, A. K.; Levental, I.
10.1101/2024.08.28.610209 — biophysics — Posted on 2024-08-30
268 A dual ribosomal system in the zebrafish soma and germline
Shah, A. N.; Leesch, F.; Lorenzo-Orts, L.; Grundmann, L.; Novatchkova, M.; Haselbach, D.; Calo, E.; Pauli, A.
10.1101/2024.08.29.610041 — developmental biology — Posted on 2024-08-30
269 Phase separation promotes Atg8 lipidation for autophagy progression
Fujioka, Y.; Tsuji, T.; Kotani, T.; Kumeta, H.; Kakuta, C.; Fujimoto, T.; Nakatogawa, H.; Noda, N. N.
10.1101/2024.08.29.610189 — cell biology — Posted on 2024-08-30
270 Single-nucleosome imaging reveals principles of transient multiscale chromatin unfolding triggered by histone ADP-ribosylation at DNA lesions
GARCIA FERNANDEZ, F.; Chapuis, C.; PARK, J.; Pinto Jurado, E.; Imburchia, V.; Longarini, E. J.; Taddei, A.; Sokolovska, N.; Matic, I.; Huet, S.; Mine Hattab, J.
10.1101/2024.08.28.610034 — cell biology — Posted on 2024-08-30
271 Imaging the interactions of chimeric antigen receptor-expressing T-cells with colorectal cancer cells
Banik, D.; Ward, C.; Zhang, Z.; Heraghty, D.; Suresh, P.; Li, B.; Kedia, S.; Davis, S.; Roy, J.; Chapman, M.; Mahata, B.; Klenerman, D.
10.1101/2024.08.29.610222 — immunology — Posted on 2024-08-30
272 Invariant Natural Killer T cells control positively and negatively the development of hepatocellular carcinoma
Papanastasatou, M.; Gioulbasani, M.; Nakou, E.; Galaras, A.; Rubio-Tomas, T.; Talianidis, I.; Eliopoulos, A.; Hatzis, P.; Verykokakis, M.
10.1101/2024.08.29.610221 — immunology — Posted on 2024-08-30
273 Dietary zinc restriction mimics protein restriction and extends lifespan in Drosophila
Kosakamoto, H.; Aikawa, H.; Kitazawa, S.; Sakuma, C.; Okada, R.; Miura, M.; Obata, F.
10.1101/2024.08.28.610190 — physiology — Posted on 2024-08-30
274 Impaired S-nitrosylation of Cx43 prevents arrhythmogenicity and myocardial injury upon cardiac stress in Duchenne Muscular Dystrophy
Munoz, M. F.; Quan, J. J.; Nguyen, T. T.; Nuno, J.; Sheehy, A.; Burboa, P. C.; Gaete, P. S.; Lillo, M. A.; Contreras, J. E.
10.1101/2024.08.29.610357 — physiology — Posted on 2024-08-30
275 The amyloid oligomer modulator anle138b has disease modifying effects in a human IAPP transgenic mouse model of type 2 diabetes mellitus (hIAPP Ob/Ob mice)
Hoppener, J.; Griesinger, C.; Alabariqi, M. M. H.; Vassallo, N.; Eijkelkamp, N.; Giese, A.; Baauw, S. M. G.; Fens, S.; Ryazanov, S.; Leonov, A.; Willemen, H. L. D. M.; Gerritsen, B.; Stathonikos, N.; Khemtemourian, L.; Seychell, R. M.; El Saghir, A.; Versteeg, S.
10.1101/2024.08.27.609850 — pathology — Posted on 2024-08-30
276 Integer topological defects provide a new way to quantify and classify cell sheets
Zhao, Z.; Li, H.; Yao, Y.; Zhao, Y.; Serra, F.; Kawaguchi, K.; Zhang, H.; Chate, H.; Sano, M.
10.1101/2024.08.28.610106 — biophysics — Posted on 2024-08-30
278 Exploiting XAI maps to improve MS lesion segmentation and detection in MRI
Spagnolo, F.; Molchanova, N.; Ocampo Pineda, M.; Melie-Garcia, L.; Bach Cuadra, M.; Granziera, C.; Andrearczyk, V.; Depeursinge, A.
10.1101/2024.08.29.610090 — bioengineering — Posted on 2024-08-30
279 Isotope analysis of bird eye lens provides early-life information
Hasegawa, E. A.; Matsubayashi, J.; Tayasu, I.; Goto, T.; Inoue, H.; Rossberg, A. G.; Yoshimizu, C.; Hasegawa, M.; Akasaka, T.
10.1101/2024.08.28.610164 — ecology — Posted on 2024-08-30
283 CRISPR/dCas-mediated counter-silencing: Reprogramming dCas proteins into antagonists of xenogeneic silencers
Wiechert, J.; Badia Roige, B.; Dohmen-Olma, D.; Hindra, H.; Zhang, X.; Elliot, M.; Frunzke, J.
10.1101/2024.08.29.610263 — microbiology — Posted on 2024-08-30
284 Global brain asymmetry and its variations in aging and related diseases
Hu, H.; Pu, Y.; Abuduaini, Y.; Wang, X.; Francks, C.; Thompson, P. M.; Kong, X.-Z.
10.1101/2024.08.29.610247 — neuroscience — Posted on 2024-08-30
286 Estrus-Tracking Cortical Neurons Integrate Social cues and Reproductive states to Adaptively Control Sexually Dimorphic Sociosexual Behaviors
Wang, Y.; Song, X.; Chen, X.; Zhou, Y.; Ma, J.; Zhang, F.; Wei, L.; Qi, G.; Yadav, N.; Miao, B.; Yan, Y.; Yuan, G.; Mi, D.; Rajasethupathy, P.; Ibanez-Tallon, I.; Jia, X.; Heintz, N.; Li, K.
10.1101/2024.08.30.610466 — neuroscience — Posted on 2024-08-30
287 GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine
Yamamoto, T.; Ueji, K.; Mizuta, H.; Inui-Yamamoto, C.; Kumamoto, N.; Shibata, Y.; Ugawa, S.
10.1101/2024.08.30.610470 — neuroscience — Posted on 2024-08-30
288 Movement-related activity in the internal globus pallidus of the parkinsonian macaque
Kase, D.; Zimnik, A. J.; Han, Y.; Harsch, D. R.; Bacha, S.; Cox, K. M.; Bostan, A. C.; Richardson, R. M.; Turner, R. S.
10.1101/2024.08.29.610310 — neuroscience — Posted on 2024-08-30
289 Developmental transformations of Purkinje cells tracked by DNA electrokinetic mobility
Brandenburg, C.; Crutcher, G. W.; Romanowski, A. J.; Donofrio, S. G.; Duraine, L. R.; Owusu-Mensah, R. N. A.; Sugihara, I.; Blatt, G. J.; Sillitoe, R. V.; Poulopoulos, A.
10.1101/2024.08.29.610366 — neuroscience — Posted on 2024-08-30
291 Transformations in prefrontal ensemble activity underlying rapid threat avoidance learning
Gabriel, C. J.; Gupta, T. A.; Sanchez-Fuentes, A.; Zeidler, Z. E.; Wilke, S. A.; DeNardo, L. A.
10.1101/2024.08.28.610165 — neuroscience — Posted on 2024-08-30
293 Liprin-α/RIM complex regulates the dynamic assembly of presynaptic active zones via liquid-liquid phase separation
Jin, G.; Campos, J.; Liu, Y.; de la Cruz, B. M.; Zhang, S.; Liang, M.; Li, K.; Xie, X.; Yu, C.; Sterky, F.; Acuna, C.; Wei, Z.
10.1101/2024.08.29.610253 — neuroscience — Posted on 2024-08-30
295 Plasmodesmal closure elicits stress responses
Tee, E.; Breakspear, A.; Papp, D.; Thomas, H. R.; Walker, C.; Bellandi, A.; Faulkner, C.
10.1101/2024.05.08.593115 — plant biology — Posted on 2024-08-30
296 Chemotherapy-treated breast cancer cells activate the Wnt signaling pathway to enter a diapause-DTP state.
Lluis, F.; Ellaithy, Y.; Abreu de Oliveira, W. A.; Pabba, A.; Qualizza, A.; Richard, F.; Athanasouli, P.; Luci, C. R.; De Wispelaere, W.; Mourao, L.; Hamer, S.; Moens, S.; De Jaime-Soguero, A.; Francesca Baietti, M.; Hutten, S. J.; Jonkers, J.; Sammut, S.-J.; Soenen, S. J.; Scheele, C. L.; Bruna, A.; Desmedt, C.; Annibali, D.
10.1101/2024.03.08.584051 — cancer biology — Posted on 2024-08-30
297 Structural basis of interdomain communication in PPARγ
Mosure, S. A.; Munoz-Tello, P.; Kuo, K.-T.; MacTavish, B.; Yu, X.; Scholl, D.; Williams, C. C.; Strutzenberg, T. S.; Li, J.; Bass, J.; Brust, R.; Kalkhoven, E.; Deniz, A. A.; Griffin, P. R.; Kojetin, D.
10.1101/2022.07.13.499031 — biophysics — Posted on 2024-08-30
298 Emergent collective alignment gives competitive advantage to longer cells during range expansion
van den Berg, N.; Thijssen, K.; Nguyen, T. T.; Sarlet, A.; Cordero, M.; Vazquez, A. G.; Mitarai, N.; Doostmohammadi, A.; Jauffred, L.
10.1101/2024.01.26.577059 — biophysics — Posted on 2024-08-30
301 Extensive population structure highlights an apparent paradox of stasis in the impala (Aepyceros melampus)
Garcia-Erill, G.; Wang, X.; Rasmussen, M. S.; Quinn, L.; Khan, A.; Bertola, L. D.; Santander, C. G.; Balboa, R. F.; Ogutu, J. O.; Pecnerova, P.; Hanghoej, K.; Kuja, J.; Nursyifa, C.; Masembe, C.; Muwanika, V.; Bibi, F.; Moltke, I.; Siegismund, H. R.; Albrechtsen, A.; Heller, R.
10.1101/2024.04.19.590257 — evolutionary biology — Posted on 2024-08-30
302 Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretionin extracellular vesicles
Rodrigues-Junior, D. M.; Saez-Ibanez, A. R.; Terabayashi, T.; Daubel, N.; Makinen, T.; Idevall-Hagren, O.; Ferby, I.; Moustakas, A.; Ferby, I.
10.1101/575449 — cell biology — Posted on 2024-08-30
303 The transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay
Kelbert,, M.; Jordan-Pla, A.; de-Miguel-Jimenez, L.; Garcia-Martinez, J.; Selitrennik, M.; Guterman,, A.; Henig,, N.; Granneman,, S.; Perez-Ortin, J. E.; Chavez, S.; Choder, M.
10.1101/2023.09.13.557510 — molecular biology — Posted on 2024-08-30
304 RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii: a key mechanism in parasite motility and invasion
Haase, R.; Ren, B.; Dos Santos Pacheco, N.; Visentin, R.; Maco, B.; Mondragon Flores, R.; Vadas, O.; Soldati-Favre, D.
10.1101/2024.08.29.610260 — microbiology — Posted on 2024-08-30
306 DNA damage drives antigen diversification through mosaic VSG formation in Trypanosoma brucei
Smith, J. E.; Wang, K. J.; Kennedy, E. M.; Hakim, J. M.; So, J.; Beaver, A. K.; Magesh, A.; Gilligan-Steinberg, S. D.; Zheng, J.; Zhang, B.; Moorthy, D. N.; Akin, E. H.; Mwakibete, L.; Mugnier, M. R.
10.1101/2024.03.22.582209 — microbiology — Posted on 2024-08-30
307 Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomiasis
Gruschow, S.; Steketee, P. C.; Matthews, K. R.; Morrison, L. J.; White, M. F.; Grey, F.
10.1101/2024.08.29.610254 — microbiology — Posted on 2024-08-30
310 A deep-learning based analysis framework for ultra-high throughput screening time-series data
Balzerowski, P.; Hebing, L.; Lima, F. d. A. e.; Manesso, E.; Mueller, T.; Diedam, H.; Gnutt, D.
10.1101/2024.08.22.609110 — bioinformatics — Posted on 2024-08-30
312 Less, but more: new insights from appendicularians on chordate Fgf evolution and the divergence of tunicate lifestyles.
Sanchez-Serna, G.; Badia-Ramentol, J.; Bujosa, P.; Ferrandez-Roldan, A.; Torres-Aguila, N.; Fabrega-Torrus, M.; Wibisana, J. N.; Mansfield, M. J.; Plessy, C.; Luscombe, N. M.; Albalat, R.; Canestro, C.
10.1101/2024.08.30.610304 — evolutionary biology — Posted on 2024-08-30
317 SLC35A2 modulates paramyxovirus fusion events during infection
Yang, Y.; Wang, Y.; Campbell, D.; Lee, H.-W.; Wang, L.; Baldridge, M.; Lopez, C. B.
10.1101/2024.08.27.609835 — microbiology — Posted on 2024-08-30
319 Hypothalamic control of noradrenergic neurons stabilizes sleep
Broglia, G.; Corsi, G.; Prouvot Bouvier, P.-H.; Vassalli, A.; Tafti, M.; Bandarabadi, M.
10.1101/2023.10.22.563502 — neuroscience — Posted on 2024-08-30
322 Conjugation of dn-OPDA with amino acids inhibits its hormonal bioactivity in Marchantia polymorpha
Liang, W.; Zamarreno, A. M.; Torres-Montilla, S.; de la Torre, A.; Totozafy, J. C.; Kaji, T.; Ueda, M.; Corso, M.; Garcia-Mina, J. M.; Solano, R.; Chini, A.
10.1101/2024.08.27.609933 — plant biology — Posted on 2024-08-30
323 Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P
Hoang, D.-H.; Bouviere, J.; Galvis, J.; Moulle, P.; Migliavacca, E.; Juban, G.; Liot, S.; Stuelsatz, P.; Le Grand, F.; Feige, J. N.; Mounier, R.; Chazaud, B.
10.1101/2024.08.28.610036 — physiology — Posted on 2024-08-30
324 Amputation Triggers Long-Range Epidermal Permeability Changes in Evolutionarily Distant Regenerative Organisms
Dooling, K. E.; Kim, R. T.; Kim, E. M.; Chen, E.; Abouelela, A.; Tajer, B. J.; Lopez, N. J.; Paoli, J. C.; Powell, C. J.; Luong, A. G.; Wu, S. Y. C.; Thornton, K. N.; Singer, H. D.; Savage, A. M.; Bateman, J.; DiTommaso, T.; Payzin-Dogru, D.; Whited, J. L.
10.1101/2024.08.29.610385 — physiology — Posted on 2024-08-30
327 Translation elongation as a rate limiting step of protein production
Lyons, E. F.; Devanneaux, L. C.; Muller, R. Y.; Freitas, A. V.; Meacham, Z. A.; McSharry, M. V.; Trinh, V. N.; Rogers, A. J.; Ingolia, N. T.; Lareau, L. F.
10.1101/2023.11.27.568910 — molecular biology — Posted on 2024-08-30
330 Individualized Cerebellar Damage Predicts the Behavioral Disorders in Children with Brainstem Tumors
Jia, H.; Wang, K.; Zhang, M.; Gu, G.; Mai, Y.; Wu, X.; Chu, C.; Yin, X.; Zhang, P.; Fan, L.; Zhang, L.
10.1101/2024.08.01.606261 — neuroscience — Posted on 2024-08-30
331 Nuclear assembly in giant unilamellar vesicles encapsulating Xenopus egg extract
Takamori, S.; Mimura, H.; Osaki, T.; Kondo, T.; Shintomi, M.; Shintomi, K.; Ohsugi, M.; Takeuchi, S.
10.1101/2024.06.25.600006 — synthetic biology — Posted on 2024-08-30
332 Phase behaviour of hnRNPA1 low-complexity domain mutants described by different sequence-dependent models
Feito, A.; Sanchez-Burgos, I.; Tejero, I.; Sanz, E.; Rey, A.; Collepardo-Guevara, R.; Tejedor, A. R.; Espinosa, J. R.
10.1101/2024.08.28.610132 — biophysics — Posted on 2024-08-30
342 The archaeal family 3 polyphosphate kinase reveals a function of polyphosphate as energy buffer under low energy charge
Hoefmann, S.; Schmerling, C.; Stracke, C.; Niemeyer, F.; Schaller, T.; Snoep, J. L.; Braesen, C.; Siebers, B.
10.1101/2024.08.28.610084 — microbiology — Posted on 2024-08-29
343 The SP140-RESIST pathway regulates interferon mRNA stability and antiviral immunity
Witt, K. C.; Dziulko, A.; An, J.; Lee, O. V.; Liu, G.; Lari, A. C.; Chavez, R.; Turner, D. J.; Cheng, A.; Kotov, D. I.; Abraham, P.; Lee, A. Y.; Dhaliwal, H.; Coscoy, L.; Glaunsinger, B.; Chuong, E.; Vance, R.
10.1101/2024.08.28.610186 — immunology — Posted on 2024-08-29
347 Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency
Joushomme, A.; Desilets, A.; Champagne, W.; Hassanzadeh, M.; Lemieux, G.; Gravel-Trudeau, A.; Lepage, M.; Lafreniere, S.; Froehlich, U.; List, K.; Boudreault, P.-L.; Leduc, R.
10.1101/2024.08.28.609965 — pharmacology and toxicology — Posted on 2024-08-29
351 Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry
Welp, L. M.; Sachsenberg, T.; Wulf, A.; Chernev, A.; Horokhovskyi, Y.; Neumann, P.; Pasen, M.; Siraj, A.; Raabe, M.; Johannsson, S.; Schmitzova, J.; Netz, E.; Pfeuffer, J.; He, Y.; Fritzemeier, K.; Delanghe, B.; Viner, R.; Vos, S.; Cramer, P.; Ficner, R.; Liepe, J.; Kohlbacher, O.; Urlaub, H.
10.1101/2024.08.29.610268 — biochemistry — Posted on 2024-08-29
352 Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity
Tamir, T. Y.; Chaudhary, S.; Li, A. X.; Trojan, S. E.; Flower, C. T.; Vo, P.; Cui, Y.; Davis, J. C.; Mukkamala, R. S.; Venditti, F. N.; Hillis, A. L.; Toker, A.; Vander Heiden, M. G.; Spinelli, J. B.; Kennedy, N. J.; Davis, R. J.; White, F. M.
10.1101/2024.08.28.609894 — biochemistry — Posted on 2024-08-29
353 The C2 domain augments Ras GTPase Activating Protein catalytic activity
Paul, M. E.; Chen, D.; Vish, K. J.; Lartey, N. L.; Hughes, E.; Freeman, Z. T.; Saunders, T.; Stiegler, A. L.; King, P. D.; Boggon, T. J.
10.1101/2024.08.29.609784 — biochemistry — Posted on 2024-08-29
355 A Hybrid Type I and II Polyketide Synthases Yields Distinct Aromatic Polyketides
Zhao, L. Y.; Shi, J.; Xu, Z. Y.; Sun, J. L.; Yan, Z. Y.; Tong, Z. W.; Tan, R. X.; Jiao, R. H.; Ge, H. M.
10.1101/2024.08.28.610196 — biochemistry — Posted on 2024-08-29
356 Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq
Forino, N. M.; Woo, J. Z.; Zaug, A. J.; Jimenez, A. G.; Edelson, E.; Cech, T. R.; Rouskin, S.; Stone, M.
10.1101/2023.10.04.560962 — biochemistry — Posted on 2024-08-29
357 Genetic regulation of nascent RNA maturation revealed by direct RNA nanopore sequencing
Choquet, K.; Chaumont, L.-P.; Bache, S.; Baxter-Koenigs, A. R.; Churchman, L. S.
10.1101/2024.08.29.610338 — genomics — Posted on 2024-08-29
358 DNA replication in primary hepatocytes without the six-subunit ORC
Przanowska, R. K.; Chen, Y.; Uchida, T. O.; Shibata, E.; Hao, X.; Rueda, I. S.; Jensen, K.; Przanowski, P.; Trimboli, A.; Shibata, Y.; Leone, G.; Dutta, A.
10.1101/2024.04.04.588006 — genetics — Posted on 2024-08-29
359 Trait-space disparity in fish communities spanning 380 million years from the Late Devonian to present
Llewelyn, J. S.; Long, J. A.; Cloutier, R.; Clement, A. M.; Strona, G.; Saltre, F.; Lee, M. S. Y.; Choo, B.; Trinajstic, K.; Vanhaesebroucke, O.; Bradshaw, C. J. A.
10.1101/2024.08.29.610219 — evolutionary biology — Posted on 2024-08-29
363 ONE-STEP tagging: a versatile method for rapid site-specificintegration by simultaneous reagent delivery
Migliori, V.; Bruntraeger, M.; Guylev, I.; Burgold, T.; Lichou, F.; Trinh, A.; Washer, S. J.; Jones, C.; Trynka, G.; Bassett, A. R.
10.1101/2024.08.29.610246 — molecular biology — Posted on 2024-08-29
366 RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii: a key mechanism in parasite motility and invasion
Haase, R.; Ren, B.; Dos Santos Pacheco, N.; Visentin, R.; Maco, B.; Mondragon Flores, R.; Vadas, O.; Soldati-Favre, D.
10.1101/2024.08.29.610260 — microbiology — Posted on 2024-08-29
371 Co-zorbs: Motile, multispecies biofilms aid transport of diverse bacterial species
Magesh, S.; Schrope, J.; Mercado-Soto, N.; Li, C.; Hurley, A.; Huttenlocher, A.; Beebe, D. J.; Handelsman, J.
10.1101/2024.08.29.607786 — microbiology — Posted on 2024-08-29
374 FAIR assessment of MINERVA as an opportunity to foster open science and scientific crowdsourcing in systems biomedicine
Balaur, I.; Welter, D.; Rougny, A.; Inau, E. T.; Mazein, A.; Ghosh, S.; Schneider, R.; Waltemath, D.; Ostaszewski, M.; Satagopam, V.
10.1101/2024.08.28.610042 — systems biology — Posted on 2024-08-29
375 De novo-designed minibinders expand the synthetic biology sensing repertoire
Weinberg, Z. Y.; Soliman, S. S.; Kim, M. S.; Shah, D. H.; Chen, I. P.; Ott, M.; Lim, W. A.; El-Samad, H.
10.1101/2024.01.12.575267 — synthetic biology — Posted on 2024-08-29
377 Unveiling the influence of tumor and immune signatures on immune checkpoint therapy in advanced lung cancer
Kim, N.; Park, S.; Jo, A.; Eum, H. H.; Kim, H. K.; Lee, K.; Cho, J. H.; Ku, B. M.; Jung, H. A.; Sun, J.-M.; Lee, S.-H.; Ahn, J. S.; Lee, J.-I.; Choi, J. W.; Jeong, D.; Na, M.; Kang, H.; Kim, J. Y.; Choi, J. K.; Lee, H.-O.; Ahn, M.-J.
10.1101/2024.04.15.589544 — bioinformatics — Posted on 2024-08-29
381 Activity of FoxP2-positive neurons is associated with tadpole begging behavior
Ludington, S. C.; McKinney, J. E.; Butler, J. M.; Goolsby, B. C.; Callan, A. A.; Gaines-Richardson, M.; O'Connell, L. A.
10.1101/2023.05.26.542531 — animal behavior and cognition — Posted on 2024-08-29
382 Fast Low-Input Efficient Hi-C
Guetta, M.; Avidan, N.; Kariti, H.; Davis, L.; Shemer, R.; Elliot, E.; Kaplan, N.
10.1101/2024.08.28.609956 — genomics — Posted on 2024-08-29
383 The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development.
Finer, G.; Khan, M. D.; Zhou, Y.; Gadhvi, G.; Yacu, G. S.; Park, J.-S.; Gomez, R. A.; Sequeira-Lopez, M. L.; Quaggin, S. E.; Winter, D. R.
10.1101/2024.08.14.607910 — developmental biology — Posted on 2024-08-29
388 Altered Copper Transport in Oxidative Stress-Dependent Brain Endothelial Barrier Dysfunction Associated with Alzheimer's Disease
Hossain, M. S.; Das, A.; Rafiq, A. M.; Deak, F.; Bagi, Z.; Outlaw, R.; Varadarajan, S.; Yamamoto, M.; Kaplan,, J. H.; Ushio-Fukai, M.; Fukai, T.
10.1101/2024.08.28.610108 — neuroscience — Posted on 2024-08-29
389 FREQuency-resolved brain Network Estimation via Source Separation (FREQ-NESS)
Rosso, M.; Fernandez-Rubio, G.; Keller, P.; Brattico, E.; Vuust, P.; Kringelbach, M. L.; Bonetti, L.
10.1101/2024.08.28.610155 — neuroscience — Posted on 2024-08-29
393 Regulation of transposons within medium spiny neurons enables molecular and behavioral responses to cocaine
Silva, G. M.; Picone, J. A.; Kaplan, A. L.; Park, C. R.; Lira, D. P.; Kim, R. K.; Truby, N. L.; Neve, R. L.; Cui, X.; Hamilton, P. J.
10.1101/2024.08.28.610134 — neuroscience — Posted on 2024-08-29
394 The assembly of cancer-specific ribosomes by the lncRNA LISRR suppresses melanoma anti-tumour immunity
Cinque, S.; Verheyden, Y.; Adnane, S.; Marino, A.; Katopodi, V.; Demesmaeker, E.; Knezevic, Z.; Hanache, S.; Vendramin, R.; Cuomo, A.; Pozniak, J.; Calabuig, A. C.; Tabruyn, S.; Bechter, O.; Baietti, M. F.; Groaz, E.; Bonaldi, T.; Leucci, E.
10.1101/2023.01.06.523012 — cancer biology — Posted on 2024-08-29
398 The vprAB-ompV-virK operon of Vibrio cholerae senses antimicrobial peptides and activates the expression of multiple resistance systems
Mathieu-Denoncourt, A.; Whitfield, G. B.; Vincent, A. T.; Pauze-Foixet, J.; Mahieddine, F.; Brun, Y. V.; Duperthuy, M.
10.1101/2024.08.28.609885 — microbiology — Posted on 2024-08-29
401 Inflammatory pain in mice induces light cycle-dependent effects on sleep architecture
Burek, D. J.; Mohamad Ibrahim, K.; Hall, A. G.; Sharma, A.; Musiek, E. S.; Moron, J. A.; Carlezon, W. A.
10.1101/2024.08.28.610124 — neuroscience — Posted on 2024-08-29
404 A neural correlate of individual odor preference in Drosophila
Churgin, M.; Lavrentovich, D.; Smith, M. A.-Y.; Gao, R.; Boyden, E. S.; de Bivort, B. L.
10.1101/2021.12.24.474127 — neuroscience — Posted on 2024-08-29
406 Altered functional connectivity and spatiotemporal dynamics in individuals with sleep disorders
Daley, L.; Saini, P.; Watters, H.; Bassil, Y.; Schumacher, E.; Trotti, L. M.; Keilholz, S.
10.1101/2024.08.28.610147 — pathology — Posted on 2024-08-29
408 Phase behaviour of hnRNPA1 low-complexity domain mutants described by different sequence-dependent models
Feito, A.; Sanchez-Burgos, I. R.; Tejero, I.; Sanz, E.; Rey, A.; Collepardo-Guevara, R.; Tejedor, A. R.; Rene Espinosa, J.
10.1101/2024.08.28.610132 — biophysics — Posted on 2024-08-29
410 Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing
Carrozzo, I.; Maule, G.; Gentile, C.; Umbach, A.; Ciciani, M.; Guidone, D.; De Santis, M.; Petris, G.; Galietta, L. J. V.; Arosio, D.; Cereseto, A.
10.1101/2024.08.28.610115 — bioengineering — Posted on 2024-08-29
412 SNAP-tag2: faster and brighter protein labeling
Kühn, S.; Nasufovic, V.; Wilhelm, J.; Kompa, J.; de Lange, E. M. F.; Lin, Y.-H.; Egoldt, C.; Fischer, J.; Lennoi, A.; Tarnawski, M.; Reinstein, J.; Vlijm, R.; Hiblot, J.; Johnsson, K.
10.1101/2024.08.28.610127 — biochemistry — Posted on 2024-08-29
415 Profiling extremophile bacterial communities recovered from a mining tailing against soil ecosystems through comparative genome-resolved metagenomics and evolutionary analysis
Rojas, M. A.; Serrano, G.; Torres, J.; Ortega, J.; Galvez, G.; Vilches, E.; Parra, V.; Reyes-Jara, A.; Maracaja-Coutinho, V.; Pizarro, L.; Latorre, M.; Di Genova, A.
10.1101/2024.08.28.610100 — genomics — Posted on 2024-08-29
419 Live Cell Painting: image-based profiling in live cells using Acridine Orange
Garcia-Fossa, F.; Moraes-Lacerda, T.; Rodrigues-da-Silva, M.; Diaz-Rohrer, B.; Singh, S.; Carpenter, A. E.; Cimini, B. A.; de Jesus, M. B.
10.1101/2024.08.28.610144 — cell biology — Posted on 2024-08-29
421 O-glycosylation contributes to mammalian glycoRNA biogenesis
Porat, J.; Watkins, C.; Jin, C.; Xie, Y.; Tan, X.; Lebedenko, C.; Hemberger, H.; Shin, W.; Chai, P.; Collins, J. J.; Garcia, B. A.; Bojar, D.; Flynn, R. A.
10.1101/2024.08.28.610074 — molecular biology — Posted on 2024-08-29
423 A two-dose regimen of Qβ virus-like particle-based vaccines elicit protective antibodies against heroin and fentanyl
Romano, I. G.; Johnson-Weaver, B. T.; Core, S. B.; Jamus, A. N.; Brackeen, M.; Blough, B.; Dey, S.; Huang, Y.; Staats, H. F.; Wetsel, W. C.; Chackerian, B.; Frietze, K. M.
10.1101/2024.08.28.608988 — immunology — Posted on 2024-08-29
424 Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signalling in Drosophila
Vincze, V.; Esküdt, Z.; Feher-Juhasz, E.; Chhatre, A. S.; Jipa, A.; Csordos, M.; Galambos, A. R.; Börcsök, D.; Juhasz, G.; Szabo, A.
10.1101/2024.08.28.610109 — neuroscience — Posted on 2024-08-29
426 Region-specific Nucleus Accumbens Dopamine Signals Encode Distinct Aspects of Avoidance Learning
Lopez, G. C.; Van Camp, L. D.; Kovaleski, R. F.; Schaid, M. D.; Moreno-Ramos, O. A.; Awatramani, R.; Cox, J. M.; Lerner, T. N.
10.1101/2024.08.28.610149 — neuroscience — Posted on 2024-08-29
431 AMOEBA Polarizable Molecular Dynamics Simulations of Guanine Quadruplexes: from the c-Kit Proto-oncogene to HIV-1
El Ahdab, D. S.; Lagardere, L.; Hobaika, Z.; Jaffrelot Inizan, T.; Celerse, F.; Gresh, N.; Maroun, R. G.; Piquemal, J.-P.
10.1101/2024.08.28.610081 — biophysics — Posted on 2024-08-29
433 Investigation of Lipid-PEG Anchorage of Proteins onto Mesenchymal Stem Cell Derived Extracellular Vesicles for Intracellular Delivery: A Quantitative Assessment
Marquant, A.; Berthelot, J.; Bich, C.; Ibn Elfekih, Z.; Simon, L.; Robin, B.; Chopineau, J.; Tianpei Wang, D.; Jay Emerson, S.; Wang, A.; Benedetti, C.; Langlois, S.; Guglielmi, L.; Martineau, P.; Aubert-Pouessel, A.; Morille, M.
10.1101/2024.08.28.610030 — bioengineering — Posted on 2024-08-29
438 Quantifying immune cell telomere content at single-cell resolution in context of PD-1 checkpoint immunotherapy
Engel, N. L.; Herzel, L.; Surmely, J.; Friess, H.; Simon, M.; Brors, B.; Imbusch, C.; Feuerbach, L.
10.1101/2024.08.28.609339 — immunology — Posted on 2024-08-29
439 Mouse olfactory system acts as anemo-detector and -discriminator
Mahajan, S.; Tamboli, S.; Das, S.; Bhattacharjee, A. S.; Pardasani, M.; Srikanth, P.; Marathe, S. D.; Adlakha, A.; Ranjan, L.; Pandey, S.; Abraham, N. M.
10.1101/2024.08.28.610087 — neuroscience — Posted on 2024-08-29
442 Dopamine and temporal discounting: revisiting pharmacology and individual differences
Smith, E.; Theis, H.; van Eimeren, T.; Knauth, K.; Tuzsus, D.; Zhang, L.; Mathar, D.; Peters, J.
10.1101/2024.08.28.610170 — neuroscience — Posted on 2024-08-29
448 Peripheral nervous system mediates body-wide stem cell activation for limb regeneration
Payzin-Dogru, D.; Blair, S. J.; Jena, S. G.; Wilson, S. E.; Kim, R. T.; Savage, A. M.; Kriukov, E.; Cat, V.; Cammarata, L. V.; Bothe, V.; Erdogan, B.; Hossain, S.; Lopez, N.; Losner, J.; Velazquez Matos, J. C.; Min, S.; Dooling, K. E.; Freedman, A. H.; Groves, B.; Tajer, B.; Kalu, G.; Wynn, E.; Wong, A. Y. L.; Singer, H.; Frobisch, N.; Baranov, P.; Buenrostro, J. D.; Haas, B. J.; Chiu, I. M.; Sackton, T. B.; Whited, J. L.
10.1101/2021.12.29.474455 — developmental biology — Posted on 2024-08-29
450 HIRA defines early replication initiation zones independently of their genome compartment
Karagyozova, T.; Gatto, A.; Forest, A.; Quivy, J.-P.; Marti-Renom, M. A.; Mirny, L.; Almouzni, G.
10.1101/2024.08.29.610220 — cell biology — Posted on 2024-08-29
451 CRISPR/dCas-mediated counter-silencing: Reprogramming dCas proteins into antagonists of xenogeneic silencers
Wiechert, J.; Badia Poige, B.; Dohmen-Olma, D.; Hindra, ; Zhang, X.; Elliot, M.; Frunzke, J.
10.1101/2024.08.29.610263 — microbiology — Posted on 2024-08-29
452 Columnar cholinergic neurotransmission onto T5 cells of Drosophila
Samara, E.; Schilling, T.; Ribeiro, I. M. A.; Haag, J.; Leonte, M.-B.; Borst, A.
10.1101/2024.08.28.610055 — neuroscience — Posted on 2024-08-29
453 Synaptic connectome of a neurosecretory network in the Drosophila brain
McKim, T. H.; Gera, J.; Gayban, A. J.; Reinhard, N.; Manoli, G.; Hilpert, S.; Helfrich-Forster, C.; Zandawala, M.
10.1101/2024.08.28.609616 — neuroscience — Posted on 2024-08-29
454 Age Dependent Integration of Cortical Progenitors Transplanted at the Adult CSF-Brain Interface
Pothayee, N.; Greene, G.; Jahanipour, J.; Jie, H.; Tao-Cheng, J.-H.; Petrus, E.; Maric, D.; Koretsky, A. P.
10.1101/2024.08.28.609860 — neuroscience — Posted on 2024-08-29
455 Variations of neuronal properties in the region of locus coeruleus of mice
Tortorelli, L.; Garad, M.; Megemont, M.; Haga-Yamanaka, S.; Goel, A.; Yang, H.
10.1101/2022.08.19.504582 — neuroscience — Posted on 2024-08-29
457 The transaminase-omega-amidase pathway is a redox switch in glutamine metabolism that generates alpha-ketoglutarate
Herrle, N.; Felipe Malacarne, P.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; S. Leisegang, M.; Sarakpi, T.; Wionski, S.; Lopez, M.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Guenther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Wittig, I.; H. Schulz, M.; Richards, J. B.; Gilsbach, R.; T. Denton, T.; Fleming, I.; Hannibal, L.; P. Brandes, R.; Rezende, F.
10.1101/2024.08.28.610061 — physiology — Posted on 2024-08-29
458 Selective autophagy of ribosomes balances a tradeoff between starvation survival and growth resumption
Tuomaala, J.; Sankar, D. S.; Perey, J.; Psalmon, S.; Stroustrup, N.; Dengjel, J.; Towbin, B. D.
10.1101/2024.08.28.609383 — physiology — Posted on 2024-08-29
461 Topology-Driven Negative Sampling Enhances Generalizability in Protein-Protein Interaction Prediction
Chatterjee, A.; Ravandi, B.; Haddadi, P.; Philip, N. H.; Abdelmessih, M.; Mowrey, W. R.; Ricchiuto, P.; Liang, Y.; Ding, W.; Mobarec, J. C.; Eliassi-Rad, T.
10.1101/2024.04.27.591478 — bioinformatics — Posted on 2024-08-29
463 EdgeHOG: fine-grained ancestral gene order inference at tree-of-life scale
Bernard, C.; Nevers, Y.; Karampudi, N. B. R.; Gilbert, K. J.; Train, C.; Vesztrocy, A. W.; Glover, N.; Altenhoff, A.; Dessimoz, C.
10.1101/2024.08.28.610045 — evolutionary biology — Posted on 2024-08-29
464 How Alzheimer's Abeta propagates and triggers tau pathology in intact neurons
Sasahara, T.; Hongo, S.; Ito, M.; Takino, N.; Muramatsu, S.-i.; Kakita, A.; Hoshi, M.
10.1101/2024.08.28.608712 — neuroscience — Posted on 2024-08-29
469 Extending the IICR to multiple genomes and identification of limitations of some demographic inferential methods
Chikhi, L.; Rodriguez, W.; Paris, C.; Ha-Shan, M.; Jouniaux, A.; Arredondo, A.; Nous, C.; Grusea, S.; Corujo, J.; Lourenco, I.; Boitard, S.; Mazet, O.
10.1101/2024.08.16.608273 — evolutionary biology — Posted on 2024-08-29
470 Resistance and resilience of soil microbiomes under climate change
Boyle, J. A.; Murphy, B. K.; Ensminger, I.; Stinchcombe, J. R.; Frederickson, M. E.
10.1101/2023.08.04.551981 — ecology — Posted on 2024-08-29
472 miR-146a-5p mediates inflammation-induced β cell mitochondrial dysfunction and apoptosis
Krishnan, P.; Branco, R. C. S.; Weaver, S. A.; Chang, G.; Lee, C.-C.; Syed, F.; Evans-Molina, C.
10.1101/2024.03.18.585543 — molecular biology — Posted on 2024-08-29
473 GABA-ergic inhibition in human hMT+ predicts visuo-spatial intelligence mediated through the frontal cortex
Gao, Y.; Cai, Y.-C.; Liu, D.-Y.; Yu, J.; Wang, J.; Li, M.; Xu, B.; Wang, T.; Chen, G.; Northoff, G.; Bai, R.; Song, X.
10.1101/2024.03.20.585863 — neuroscience — Posted on 2024-08-29
474 Single-Cell Stress Analysis in Tumoroids.
Rodrigues de Mercado, R.; Beslmuller, K.; Vorselen, D.; Danen, E.; Schmidt, T.
10.1101/2024.01.22.576025 — biophysics — Posted on 2024-08-29
475 CFAP410 has a bimodular architecture with a conserved surface patch on its N-terminal LRR motif for binding interaction partners
Stadler, A.; Gabriel, H. B.; De Liz, L. V.; Alonso-Gil, S.; Deng, X.; Crickley, R.; Korbula, K.; Huang, K.; Zagrovic, B.; Vaughan, S.; Sunter, J.; Dong, G.
10.1101/2022.09.21.508879 — biochemistry — Posted on 2024-08-29
476 The evolutionary dynamics of locally adaptive chromosome inversions in Mimulus guttatus
Kollar, L. M.; Stanley, L. E.; Kenchanmane Raju, S. K. M.; Lowry, D.; Niederhuth, C. E.
10.1101/2023.12.06.570460 — genomics — Posted on 2024-08-29
477 Laminin gamma1-dependent basement membranes are instrumental to ensure proper olfactory placode shape, position and boundary with the brain, as well as olfactory axon development
Tignard, P.; Pottin, K.; Geeverding, A.; Doulazmi, M.; Cabrera, M.; Fouquet, C.; Liffran, M.; Fouchard, J.; Rosello, M.; Albadri, S.; Del Bene, F.; Trembleau, A.; Breau, M. A.
10.1101/2023.06.29.547040 — developmental biology — Posted on 2024-08-29
479 The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2
Suryawanshi, R. K.; Jaishankar, P.; Correy, G. J.; Rachman, M. M.; O'Leary, P. C.; Taha, T. Y.; Zapatero-Belinchon, F. J.; McCavitt-Malvido, M.; Doruk, Y. U.; Stevens, M. G. V.; Diolaiti, M. E.; Jogalekar, M. P.; Richards, A. L.; Montano, M.; Rosecrans, J.; Matthay, M.; Togo, T.; Gonciarz, R. L.; Gopalkrishnan, S.; Neitz, R. J.; Krogan, N. J.; Swaney, D. L.; Shoichet, B. K.; Ott, M.; Renslo, A. R.; Ashworth, A.; Fraser, J. S.
10.1101/2024.08.08.606661 — immunology — Posted on 2024-08-29
495 Spatial Dynamics of the Developing Human Heart
Lazar, E.; Mauron, R.; Andrusivova, Z.; Foyer, J.; He, M.; Larsson, L.; Shakari, N.; Salas, S. M.; Avenel, C.; Sariyar, S.; Hansen, J. N.; Vicari, M.; Czarnewski, P.; Braun, E.; Li, X.; Bergmann, O.; Sylven, C.; Lundberg, E.; Linnarsson, S.; Nilsson, M.; Sundstrom, E.; Adameyko, I.; Lundeberg, J.
10.1101/2024.03.12.584577 — developmental biology — Posted on 2024-08-29
497 GageTracker: a tool for dating gene age by micro- and macro-synteny with high speed and accuracy
Fang, C.; Dong, C.; Wang, C.; Xiong, F.; Lu, S.; Fang, W.; Li, T.; Gan, X.; Yang, L.; Zeng, H.; He, S.
10.1101/2024.08.28.610050 — bioinformatics — Posted on 2024-08-29
499 Behavioral pharmacology of mescaline - the role of serotonin 5-HT2A, 5-HT2B, 5-HT2C and 5-HT1A receptors
Olejnikova-Ladislavova, L.; Fujakova-Lipski, M.; Sichova, K.; Danda, H.; Syrova, K.; Horacek, J.; Palenicek, T.
10.1101/2024.08.28.610032 — animal behavior and cognition — Posted on 2024-08-29
500 Cellular processing of beneficial de novo emerging proteins
Houghton, C. J.; Castilho Coelho, N.; Chiang, A.; Hedayati, S.; Parikh, S. B.; Ozbaki-Yagan, N.; Wacholder, A.; Iannotta, J.; Berger, A.; Carvunis, A.-R.; O'Donnell, A. F.
10.1101/2024.08.28.610198 — evolutionary biology — Posted on 2024-08-29
505 Accurate antibody loop structure prediction enables zero-shot design of target-specific antibodies
Bang, Y.; Choi, Y.-A.; Gu, J.; Kwon, S.; Lee, D.; Lee, E. S.; Lee, M. S.; Lee, S.; Lee, S.; Lee, S. J.; Lim, J.; Maeng, J. Y.; Nam, J.; Noh, J.; Oh, H.; Park, S.-Y.; Park, T.; Seo, S.; Seok, C.; Song, M. Y.; Won, J.; Woo, H.; Yang, J.; Yoon, M. J.; Bae, W.; Kim, J.; Lee, D.; Lee, J.; Lee, Y.; Yu, H.
10.1101/2024.08.23.609114 — bioengineering — Posted on 2024-08-29
506 Evolution of a Eukaryotic Transcription Factor's co-TF Dependence Involves Multiple Intrinsically Disordered Regions Affecting Activation and Autoinhibition
Snyder, L. F.; O'Brien, E. M.; Zhao, J.; Liang, J.; Zhang, Y.; Zhu, W.; Cassier, T.; Schnicker, N. J.; Zhou, X.; Gordan, R.; He, B. Z.
10.1101/2024.04.20.590343 — evolutionary biology — Posted on 2024-08-29
508 The Fossilised Birth-Death Model is Identifiable
Truman, K.; Vaughan, T. G.; Gavryushkin, A.; Gavryushkina, A.
10.1101/2024.02.08.579547 — evolutionary biology — Posted on 2024-08-29
509 Plasticity, geographic variation and trait coordination in blue oak drought physiology
Anderegg, L. D. L.; Skelton, R. P.; Diaz, J.; Papper, P.; Ackerly, D. D.; Dawson, T. D. L.
10.1101/2023.08.20.553748 — ecology — Posted on 2024-08-29
510 Marine spatial planning to enhance coral adaptive potential
Forrest, D. L.; McManus, L. C.; Tekwa, E. W.; Schindler, D. E.; Colton, M. A.; Webster, M. M.; Fox, H. E.; Essington, T. E.; Palumbi, S. R.; Mumby, P. J.; DeFilippo, L.; Schill, S. R.; Pollock, F. J.; Pinsky, M. L.
10.1101/2024.08.27.609972 — ecology — Posted on 2024-08-29
511 Animal septins contain functional transmembrane domains
Perry, J. A.; Werner, M. E.; Omi, S.; Heck, B. W.; Maddox, P. S.; Mavrakis, M.; Maddox, A. S.
10.1101/2023.11.20.567915 — cell biology — Posted on 2024-08-29
514 Radiation of pain: Psychophysical evidence for a population coding mechanism in humans
Adamczyk, W. M.; Ramu, V.; Jackson, C.; Schulze, G.; Goldschneider, K.; Kashikar-Zuck, S.; King, C.; Coghill, R. C.
10.1101/2024.04.02.587666 — neuroscience — Posted on 2024-08-29
516 A multi-channel electrophysiology approach to non-invasively and precisely record human spinal cord activity
Nierula, B.; Stephani, T.; Bailey, E.; Kaptan, M.; Horn, U.; Pohle, L.-M.; Mouraux, A.; Maess, B.; Villringer, A.; Curio, G.; Nikulin, V. V.; Eippert, F.
10.1101/2022.12.05.519148 — neuroscience — Posted on 2024-08-28
518 SF3B1-mutant mis-splicing of UBA1 confers a targetable therapeutic vulnerability through UBA1 inhibition
Thier, J.; Hofmann, S.; Kirchhof, K.; Todisco, G.; Mortera-Blanco, T.; Barbosa, I.; Björklund, A.-C.; Deslauriers, A. G.; Papaemmanuil, E.; Papapetrou, E. P.; Hellström-Lindberg, E.; Moura, P. L.; Lundin, V.
10.1101/2024.08.28.610114 — cancer biology — Posted on 2024-08-28
520 Involvement of the cerebellum in structural connectivity enhancement in episodic migraine
Matoso, A.; Fouto, A. R.; Esteves, I.; Ruiz-Tagle, A.; Caetano, G.; da Silva, N. A.; Vilela, P.; Gil-Gouveia, R.; Nunes, R. G.; Figueiredo, P.
10.1101/2024.04.26.591265 — bioengineering — Posted on 2024-08-28
521 Ultra-Long-Term Delivery of Hydrophilic Drugs Using Injectable In Situ Cross-Linked Depots
Lee, S.; Zhao, S.; Jiang, W.; Chen, X.; Zhu, L.; Joseph, J.; Agus, E.; Mary, H. B.; Barooj, S.; Slaughter, K.; Cheung, K.; Luo, J. N.; Shukla, C.; Gao, J.; Lee, D.; Balakrishnan, B.; Jiang, C.; Gorantla, A.; Shah, P.; Woo, S.; Karp, J.; Joshi, N.
10.1101/2023.11.04.565631 — bioengineering — Posted on 2024-08-28
522 The Y951N patient mutation inactivates the intramolecular switch in human mitochondrial DNA POLgamma
Forslund, J. M. E.; Nguyen, T. V. H.; Parkash, V.; Berner, A.; Goffart, S.; Pohjoismaki, J. L. O.; Wanrooij, P. H.; Johansson, E. H.; Wanrooij, S.
10.1101/2024.08.28.610080 — biochemistry — Posted on 2024-08-28
523 Chromosome-level genome assembly and methylome profile enables insights for the conservation of endangered loggerhead sea turtles
Yen, E. C.; Gilbert, J. D.; Balard, A.; Taxonera, A.; Fairweather, K.; Ford, H. L.; Thorburn, D.-M. J.; Rossiter, S. J.; Martin-Duran, J. M.; Eizaguirre, C.
10.1101/2024.08.28.610089 — genomics — Posted on 2024-08-28
525 Promising effects of duck vaccination against highly pathogenic avian influenza, France 2023-24
Guinat, C.; Fourtune, L.; Lambert, S.; Martin, E.; Gerbier, G.; Jimenez Pellicer, A.; Guerin, J.-L.; Vergne, T.
10.1101/2024.08.28.609837 — ecology — Posted on 2024-08-28
527 The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development.
Finer, G.; Khan, M. D.; Zhou, Y.; Gadhvi, G.; Yacu, G. S.; Park, J.-S.; Gomez, R. A.; Sequeira-Lopez, M. L.; Quaggin, S. E.; Winter, D. R.
10.1101/2024.08.14.607910 — developmental biology — Posted on 2024-08-28
528 AutoMorFi: Automated Whole-image Morphometry in Fiji/ImageJ for Diverse Analyses and Discoveries
Bouadi, O.; Yao, C.; Zeng, J.; Beason, D.; Inda, N.; Malone, Z.; Yoshihara, J.; Manjally, A. V.; Johnson, C.; Cherry, J.; Chen, C.-Y.; Huang, T.-C.; Popovic, B.; Henley, M.; Liu, G.; Kharitonova, E. K.; Zeldich, E.; Aichelman, H.; Davies, S. W.; Walentek, P.; Tian, Y.; Man, H.; Ozsen, E.; Harder, K.; Gilmore, T. D.; Pitt, D.; Tay, T. L.
10.1101/2024.07.26.605357 — cell biology — Posted on 2024-08-28
529 PTEN Regulates Myofibroblast Activation in Valvular Interstitial Cells based on Subcellular Localization
Batan, D.; Tseropoulos, G.; Bishop, C.; Kirkpatrick, B. E.; Bera, K.; Khang, A.; Weiser-Evans, M. C.; Anseth, K. S.
10.1101/2024.06.30.601424 — cell biology — Posted on 2024-08-28
530 Micro-C reveals MORC/ApiAP2-mediated links between distant, functionally related genes in the human malaria parasite
Singh, P.; Serizay, J.; Couble, J.; Cabahug, M. D.; Rosa, C.; Chen, P.; Scherf, A.; Koszul, R.; Baumgarten, S.; Bryant, J. M.
10.1101/2024.08.28.610079 — molecular biology — Posted on 2024-08-28
533 Identification of a new ORF3a-E fusion subgenomic RNA of SARS-CoV-2 and its biological features in the infection process
Zhang, Y.; Zheng, H.; Li, J.; Zhang, X.; Zhang, X.; Li, J.; Li, H.; Zhao, X.; Zhang, Z.; Li, Y.; Chen, k.; Peng, S.; Zhang, Y.; Shi, H.; Liu, L.
10.1101/2024.08.28.610093 — microbiology — Posted on 2024-08-28
534 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences
Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.
10.1101/2024.03.05.583455 — microbiology — Posted on 2024-08-28
536 Sex specific knee joint soft tissue mineralization with Fibrillin-1 mutation in male Tight Skin mice.
Keenan, C.; Wang, X.; Dikmen, T.; Wen, Y.; Ramos-Mucci, L.; Shorter, E.; Abraham, D.; Bou-Gharios, G.; Poulet, B.
10.1101/2024.08.28.610095 — pathology — Posted on 2024-08-28
537 Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids
Waechtershaeuser, K. N.; Schneider, J. V.; Gessner, A.; Andrieux, G.; Kur, I.; Duschek, N.; Weigert, A.; Boerries, M.; Rieger, M. A.; Stelzer, E. H. K.; Pampaloni, F.; van Wijk, S.
10.1101/2024.08.28.610103 — cancer biology — Posted on 2024-08-28
539 Characterizing microbubble-mediated permeabilization in a vessel-on-a-chip model
Meijlink, B.; Collado Lara, G.; Bishard, K.; Conboy, J. P.; Langeveld, S. A. G.; Koenderink, G.; van der Steen, A. F. W.; de Jong, N.; Beekers, I.; Tritsch, S. J.; Kooiman, K.
10.1101/2024.08.28.609836 — bioengineering — Posted on 2024-08-28
540 Structural and kinetic insights into tRNA promoter engagement by yeast general transcription factor TFIIIC
Seifert-Davila, W.; Chaban, A.; Baudin, F.; Girbig, M.; Hauptmann, L.; Hoffmann, T.; Duss, O.; Eustermann, S.; Muller, C. W.
10.1101/2024.08.28.610035 — biochemistry — Posted on 2024-08-28
541 Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses
Park, Y.-J.; Liu, C.; Lee, J.; Brown, J. T.; Ma, C.-B.; Liu, P.; Xiong, Q.; Stewart, C.; Addetia, A.; Craig, C. J.; Tortorici, M. A.; Alshukari, A.; Starr, T.; Yan, H.; Veesler, D.
10.1101/2024.08.28.608351 — biochemistry — Posted on 2024-08-28
542 Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways
Kumar, R.; Zhang, F.; Niphadkar, S.; Onu, C.; Vijjamarri, A. K.; Greenberg, M. L.; Laxman, S.; Hinnebusch, A. G.
10.1101/2024.08.28.610059 — genetics — Posted on 2024-08-28
544 Polyunsaturated fatty acid-derived lipid mediator networks characterize COVID-19 severity and risk for critical illness
Papadaki, M.; Pavlos, E.; Dubourdeau, M.; Bailif, V.; Badirou, K.; Galani, I.-E.; Papelis, D.; Kamperi, N.; Triantafyllia, V.; Siouti, L.; Salagianni, M.; Manioudaki, M.; Paschalidis, N.; Vatsellas, G.; Koukaki, E.; Rapti, V.; Thanos, D.; Rovina, N.; Poulakou, G.; Cobat, A.; Casanova, J.-L.; Tamvakopoulos, C.; Andreakos, E.
10.1101/2024.08.28.610123 — immunology — Posted on 2024-08-28
546 High-Throughput Assay for Predicting Diarrhea Risk Using a 2D Human Intestinal Stem Cell-Derived Model
Pike, C. M.; Levi, J. A.; Boone, L. A.; Peddibhotla, S.; Johnson, J.; Zwarycz, B.; Bunger, M. K.; Thelin, W.; Boazak, E. M.
10.1101/2024.08.28.610072 — pharmacology and toxicology — Posted on 2024-08-28
547 Sustained fertility from first-wave follicle oocytes that pause their growth
Soygur, B.; Gaylord, E. A.; Foecke, M. H.; Cincotta, S. A.; Horan, T. J.; Wood, A.; Cohen, P.; Laird, D. J.
10.1101/2024.08.27.609995 — developmental biology — Posted on 2024-08-28
549 Marine spatial planning to enhance coral adaptive potential
Forrest, D. L.; McManus, L. C.; Tekwa, E. W.; Schindler, D. E.; Colton, M. A.; Webster, M. M.; Fox, H. E.; Essington, T. E.; Palumbi, S. R.; Mumby, P. J.; DeFilippo, L.; Schill, S. R.; Pollock, F. J.; Pinsky, M.
10.1101/2024.08.27.609972 — ecology — Posted on 2024-08-28
550 Information-making processes in the speaker's brain drive human conversations forward
Goldstein, A.; Wang, H.; Sheffer, T.; Schain, M.; Zada, Z.; Niekerken, L.; Aubrey, B.; Nastase, S. A.; Gazula, H.; Casto, C.; Doyle, W. K.; Friedman, D.; Devore, S.; Dugan, P.; Hassidim, A.; Brenner, M.; Matias, Y.; Devinsky, O.; Flinker, A.; Hasson, U.
10.1101/2024.08.27.609946 — neuroscience — Posted on 2024-08-28
552 Loss of the tumor suppressor NUMB drives aggressive bladder cancer through hyperactivation of a RhoA/ROCK/YAP signaling circuitry
Tucci, F. A.; Pennisi, R.; Rigiracciolo, D. C.; Filippone, M. G.; Bonfanti, R.; Romeo, F.; Freddi, S.; Soriani, C.; Rodighiero, S.; Jodice, G.; Sanguedolce, F.; Renne, G.; Fusco, N.; Di Fiore, P. P.; Pruneri, G.; Musi, G.; Vago, G.; Tosoni, D.; Pece, S.
10.1101/2024.08.27.609735 — cancer biology — Posted on 2024-08-28
553 ANLN directly interacts with PCNA to regulate UV induced translesion synthesis
Tong, B.-B.; Cao, Y.-F.; Wen, B.; Fu, T.; Deng, D.-X.; Yang, Q.-H.; Wu, Y.-Q.; Zou, H.-Y.; Liao, L.-D.; Xu, L.-Y.; Li, E.-M.
10.1101/2024.08.27.609892 — cancer biology — Posted on 2024-08-28
555 Focused Ultrasound Impels the Delivery and Penetration of Model Therapeutics into Cerebral Cavernous Malformations
Fisher, D. G.; Hoch, M. R.; Gorick, C. M.; Huchthausen, C.; Breza, V. R.; Sharifi, K. A.; Tvrdik, P.; Miller, G. W.; Price, R. J.
10.1101/2024.08.27.609060 — bioengineering — Posted on 2024-08-28
556 Hemodynamics Affects Factor XI/XII Anticoagulation Efficacy in Patient-Specific Left Atrial Models
Guerrero-Hurtado, M.; Garcia-Villalba, M.; Gonzalo, A.; Duran, E.; Martinez-Legazpi, P.; Kahn, A. M.; Chen, M. Y.; McVeigh, E.; Bermejo, J.; del Alamo, J. C.; Flores, O.
10.1101/2024.08.27.609969 — bioengineering — Posted on 2024-08-28
557 Bronchopulmonary Dysplasia with Pulmonary Hypertension Associates with Loss of Semaphorin Signaling and Functional Decrease in FOXF1 Expression
Shirazi, S. P.; Negretti, N. M.; Jetter, C. S.; Sharkey, A. L.; Garg, S.; Kapp, M. E.; Wilkins, D.; Fortier, G.; Mallapragada, S.; Banovich, N.; Wright, C. V. E.; Frank, D. B.; Kropski, J. A.; Sucre, J. M. S.
10.1101/2024.08.27.609955 — genomics — Posted on 2024-08-28
560 Survival of hepatocytes from executioner caspase activation promotes liver regeneration by enhancing JAK/STAT3 activity
Cao, Z.; Qin, L.; Liu, K.; Yao, C.; Li, E.; Hao, X.; Wang, M.; Jiang, B.; Zou, Y.; Hu, H.; Liu, Q.; Shao, C.; Gong, Y.; Sun, G.
10.1101/2024.08.28.610033 — developmental biology — Posted on 2024-08-28
563 Flanker task parameters are related to the strength of association between the ERN and anxiety: a meta-analysis
Buzzell, G. A.; Niu, Y.; Machado, E.; Dickinson, R.; Moser, J. S.; Morales, S.; Troller-Renfree, S. V.
10.1101/2024.08.27.609944 — neuroscience — Posted on 2024-08-28
564 The Human Cerebellum: A Digital Anatomical Atlas at the Level of Individual Folia
Samuelsson, J. G.; Schmahmann, J. D.; Sereno, M.; Rosen, B.; Hamalainen, M. S.
10.1101/2024.08.27.610006 — neuroscience — Posted on 2024-08-28
565 Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution
Fuhrmann, F.; Nebeling, F. C.; Musacchio, F.; Mittag, M.; Poll, S.; Mueller, M.; Ambrad Giovannetti, E.; Maibach, M.; Schaffran, B.; Burnside, E.; Chan, I. C. W.; Lagurin, A.; Reichenbach, N.; Kaushalya, S.; Fried, H.-U.; Linden, S.; Petzold, G.; Tavosanis, G.; Bradke, F.; Fuhrmann, M.
10.1101/2024.08.28.610026 — neuroscience — Posted on 2024-08-28
567 Reusing excess staple oligonucleotides for economical production of DNA origami
Isinelli, G.; Wintersinger, C.; Lill, P.; Young, O.; Deng, J.; Shih, W.; Zeng, Y.
10.1101/2024.08.27.609958 — synthetic biology — Posted on 2024-08-28
568 Enhancing Photosynthesis under Salt Stress via Directed Evolution in Cyanobacteria
Jiang, Z.; Islam, K. N.; Wolfe, M.; O'Connell, M.; Williams, D.; Florance, A.; Vinyard, D. J.; Zhang, X.; Brenner, M.; Kiss, A. J.; Liu, X.; Wang, X.
10.1101/2024.08.27.610004 — plant biology — Posted on 2024-08-28
569 Prenatal glyphosate exposure disrupts the gut-brain axis across several generations in mice.
Barnett, J. A.; Josephson, J. K.; Haskey, N. A.; Hart, M. M.; Soma, K. K.; Bandy, M. L.; McComb, C. J.; Verdugo, A.; Ghosh, S.; Letef, C.; Copp, A.; Gibon, J.; Ye, J.; Giebelhaus, R. T.; Murch, S. J.; Jung, M. M.; Gibson, D. L.
10.1101/2024.08.27.609990 — pharmacology and toxicology — Posted on 2024-08-28
570 Synergistic Cytotoxicity of Permethrin and N,N-Diethyl-Meta-Toluamide on Sinonasal Epithelial Cells
Lee, J.; Basak, S. K.; Yang, H.-H.; Sullivan, K.; Maxim, T.; Shin, D. S.; Klimas, N.; Srivatsan, E.
10.1101/2024.08.27.610017 — pharmacology and toxicology — Posted on 2024-08-28
571 MYC shapes ER-mitochondria calcium transfer by directly targeting ITPR1: implications for MYC-induced safeguard mechanisms and cancer
Ma, X.; Tsalikis, A.; Vernier, M.; Zhu, K.; El Hassani, J.; Ziegler, D.; Huna, A.; Coquet, C.; Revechon, G.; Margand, C.; Benard, F.; Czarnecka-Herok, J.; Iacono Di Cacito, I.; Koering, C.; Attignon, V.; Carrere, M.; Jollivet, F.; Mollereau, B.; Vanbelle, C.; Gandrillon, O.; Dumont, B.; Delloye-Bourgeois, C.; Hernandez-Vargas, H.; Martin, N.; Bernard, D.
10.1101/2024.08.28.610025 — cancer biology — Posted on 2024-08-28
572 Cancer-associated fibroblasts confer ALK inhibitor resistance in EML4-ALK-driven lung cancer via concurrent integrin and MET signaling
Hu, Q.; Rix, L. L. R.; Desai, B.; Miroshnychenko, D.; Li, X.; Welsh, E. A.; Fang, B.; Wright, G. M.; Chaudhary, N.; Kroeger, J. L.; Doebele, R. C.; Koomen, J. M.; Haura, E. B.; Marusyk, A.; Rix, U.
10.1101/2024.08.27.609975 — cancer biology — Posted on 2024-08-28
574 A diverse landscape of FGFR alterations and co-mutations defines novel therapeutic strategies in pediatric low-grade gliomas
Morin, E.; Apfelbaum, A. A.; Sturm, D.; Ayoub, G.; DiGiacomo, J.; Bahadur, S.; Chandarana, B.; Power, P. C.; Cusick, M. M.; Novikov, D.; Jones, R.; Vogelzang, J.; Bossi, C. C.; Malinowski, S.; Jeang, J.; Collins, J.; Oh, S.; Jeon, H.; Cameron, A.; Rechter, P.; Deleon, A.; Murugesan, K.; Montesion, M.; Albacker, L. A.; Ramkissoon, S. H.; van Tilburg, C. M.; Hardin, E. C.; Sievers, P.; Sahm, F.; yeo, K. k.; Rosenberg, T.; Chi, S.; Wright, K.; Hebert, S.; Peck, S.; Picca, A.; Larouche, V.; Renzi, S.; Bale, T.; Smith, A. A.; Touat, M.; Jabado, N.; Fischer, E. S.; Eck, M. J.; Baird, L.; Witt, O.; K
10.1101/2024.08.27.609922 — cancer biology — Posted on 2024-08-28
579 Ligand Identification using Deep Learning
Karolczak, J.; Przybylowska, A.; Szewczyk, K.; Taisner, W.; Heumann, J. M.; Stowell, M. H. B.; Nowicki, M.; Brzezinski, D.
10.1101/2024.08.27.610022 — bioinformatics — Posted on 2024-08-28
580 Reversal of contractile defects by mediating calcium homeostasis in human mini-heart models of heart failure with preserved ejection fraction (HFpEF) leads to first-in-human gene therapy clinical trial
Costa, K. D.; Wong, A. O. T.; Mak, S. Y.; Roberts, E. G.; Keung, W.; Correia, C.; Walentinsson, A.; Christoffersson, J.; Cheung, A.; Lieu, D. K.; Jennbacken, K.; Wang, Q.-D.; Hajjar, R. J.; Li, R. A.
10.1101/2024.08.27.609034 — bioengineering — Posted on 2024-08-28
583 Computational modeling of left ventricular flow using PC-CMR-derived four-dimensional wall motion
Peighambari, S. B.; Mukherjee, T.; Mendiola, E. A.; Darwish, A.; Timmins, L. H.; Pettigrew, R. I.; Shah, D. J.; Avazmohammadi, R.
10.1101/2024.08.27.609991 — bioengineering — Posted on 2024-08-28
585 Complete Chloroplast Genome Sequence and Phylogenetic Analysis of Camellia sinensis sp. Baihaozao
Chen, Z.; College of Agriculture & Biotechnology, Hunan University of Humanities, Science & Technology, ; Zhu, Y.; Demonstration Base for Innovation and Entrepreneurship in the Efficient Utilization of Local Charact, ; He, Z.; Tea Research Institute, Hunan Academy of Agricultural Sciences, ; Li, H.; Taohuayuan Agricultural Development Co., Ltd., ; Huang, J.; Gong, Y.
10.1101/2024.08.27.609997 — genomics — Posted on 2024-08-28
586 Association Between Relational Mobility and DNA Methylation in Oxytocin Receptor Gene: A Social Epigenetic Study
Li, S.; Yamada, J.; Ishihara, T.; Nishina, K.; Nishitani, S.; Sasaki, T.; Matsuda, T.; Inoue-Murayama, M.; Takagishi, H.
10.1101/2024.08.27.609977 — genetics — Posted on 2024-08-28
587 The city and forest bird flock together in a common garden: genetic and environmental effects drive urban phenotypic divergence
Thompson, M. J.; REALE, D.; Chenet, B.; Delaitre, S.; Fargevieille, A.; Romans, M.; Caro, S. P.; Charmantier, A.
10.1101/2024.08.27.609854 — evolutionary biology — Posted on 2024-08-28
591 Recapitulation of clinical features in a patient-derived xenograft mouse model of VEXAS Syndrome
Arede, L.; Coutinho, R.; Duarte, T. L.; Lopes, M.; Simoes, R.; Silva, S.; Baptista, P.; Lopes, J. M.; Faria, R.; Duarte, D.
10.1101/2024.08.27.609907 — immunology — Posted on 2024-08-28
592 EEG During Dynamic Facial Emotion Processing Reveals Neural Activity Patterns Associated with Autistic Traits in Children
Hill, A. T.; Ford, T. C.; Bailey, N. W.; Lum, J. A. G.; Bigelow, F. J.; Oberman, L. M.; Enticott, P. G.
10.1101/2024.08.27.609816 — neuroscience — Posted on 2024-08-28
598 Differential encoding of mammalian proprioception by voltage-gated sodium channels
Espino, C. M.; Nagaraja, C.; Ortiz, S.; Dayton, J. R.; Murali, A. R.; Ma, Y.; Mann, E. L.; Garlapalli, S.; Wohlgemuth, R. P.; Brashear, S. E.; Smith, L. R.; Wilkinson, K. A.; Griffith, T. N.
10.1101/2024.08.27.609982 — neuroscience — Posted on 2024-08-28
602 OsWHY1/OsTRXz/OsMORFs complex is essential for RNA modification and early chloroplast development in rice
Zheng, X.; Lu, Q.; Luo, Y.; Xu, J.; Wang, W.; Tan, M.; Liao, D.; Hong, W.; Chen, S.; Lin, C.; Wang, X.; Fan, C.; Habiba, ; Wang, X.; Li, Y.; Zhang, Y.; Lin, W.; Miao, Y.
10.1101/2024.08.28.610128 — plant biology — Posted on 2024-08-28
603 Anesthetic-like effects of ketamine in C. elegans
Seppala, K.; Reigada, I.; Matilainen, O.; Rantamaki, T.; Hanski, L.
10.1101/2024.08.28.610063 — pharmacology and toxicology — Posted on 2024-08-28
605 Glioblastoma stem cells show transcriptionally correlated spatial organization
Ayyadhury, S.; Sachamitr, P.; Kushida, M.; Park, N.; Coutinho, F.; Whitley, O.; Prinos, P.; Arrowsmith, C.; Dirks, P. B.; Pugh, T.; Bader, G.
10.1101/2024.08.27.609918 — cancer biology — Posted on 2024-08-28
610 Y chromosome STR variation reveals traditional occupation based population structure in India
Sequeira, J. J.; Chaitra, M.; Rai N R, A.; Sudeepthi, M.; Shalini, R.; Mustak, M. S.; Khanna, J.; Sharma, S.; Chilukuri, R. V. E.; Driem, G. v.; Shrivastava, P.
10.1101/2024.08.28.610024 — genetics — Posted on 2024-08-28
613 The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development
Leone, M.; Eichin, F.; Kinz, N.; Obwegs, D.; Sladky, V. C.; Rizzotto, D.; Manzl, C.; Moos, K.; Savko, C.; Jacotot, E. D.; Sussman, M.; Boerries, M.; Villunger, A.
10.1101/2024.08.27.609375 — developmental biology — Posted on 2024-08-28
614 Horizontal gene transfer can reshape bacterial warfare
Granato, E. T.; Palmer, J. D.; Kirk, C.; Sharp, C.; Shillcock, G.; Foster, K. R.
10.1101/2024.08.28.610076 — microbiology — Posted on 2024-08-28
615 Circulation of West Nile Virus and Usutu Virus in Birds in Germany, 2021 and 2022.
Schopf, F.; Sadeghi, B.; Bergmann, F.; Fischer, D.; Rahner, R.; Mueller, K.; Guenther, A.; Globig, A.; Keller, M.; Schwehn, R.; Guddorf, V.; Reuschel, M.; Fischer, L.; Krone, O.; Rinder, M.; Schuette, K.; Schmidt, V.; Heenemann, K.; Schwarzer, A.; Fast, C.; Sauter-Louis, C.; Staubach, C.; Luehken, R.; Schmidt-Chanasit, J.; Brandes, F.; Lierz, M.; Korbel, R.; Vahlenkamp, T. W.; Groschup, M. H.; Ziegler, U.
10.1101/2024.08.28.610071 — microbiology — Posted on 2024-08-28
619 Pangenomes reveal genomic signatures of microbial adaptation to experimental soil warming
Choudoir, M. J.; Narayanan, A.; Rodriguez-Ramos, D.; Simoes, R.; Efroni, A.; Sondrini, A.; DeAngelis, K. M.
10.1101/2023.03.16.532972 — microbiology — Posted on 2024-08-28
620 Fusobacterium sphaericum sp. nov., isolated from a human colon tumor, adheres to colonic epithelial cells and induces IL-8 secretion
Zepeda-Rivera, M. A.; Eisele, Y.; Baryiames, A.; Wu, H.; Mengoni, C.; Piccinno, G.; McMahon, E.; LaCourse, K. D.; Jones, D. S.; Hauner, H.; Minot, S. S.; Segata, N.; Dewhirst, F. E.; Johnston, C. D.; Bullman, S.
10.1101/2023.06.16.545380 — microbiology — Posted on 2024-08-28
622 Astrocytic LRRK2 Controls Synaptic Connectivity via Regulation of ERM Phosphorylation
Wang, S.; Baumert, R.; Sejourne, G.; Sivadasan Bindu, D.; Dimond, K.; Sakers, K.; Vazquez, L.; Moore, J. L.; Tan, C. X.; Takano, T.; Rodriguez Salazar, M. P.; Soderling, S. H.; La Spada, A. R.; Eroglu, C.
10.1101/2023.04.09.536178 — neuroscience — Posted on 2024-08-28
627 Exploring SNP Filtering Strategies: The Influence of Strict vs Soft Core
Taouk, M. L.; Featherstone, L. A.; Taiaroa, G.; Ingle, D. J.; Stinear, T. P.; Wick, R. R.
10.1101/2024.08.26.609800 — genomics — Posted on 2024-08-28
628 Moesin controls cell-cell fusion and osteoclast function
Dufrancais, O.; Verdys, P.; Plozza, M.; Metais, A.; Juzans, M.; Sanchez, T.; Bergert, M.; Halper, J.; Panebianco, C. J.; Mascarau, R.; Gence, R.; Arnaud, G.; Ben Neji, M.; Maridonneau-Parini, I.; Le Cabec, V.; Boerckel, J. D.; Pavlos, N.; Diz-Munoz, A.; Lagarrigue, F.; Blin-Wakkach, C.; Carreno, S.; Poincloux, R.; Burkhardt, J. K.; Raynaud-Messina, B.; Verollet, C.
10.1101/2024.05.13.593799 — cell biology — Posted on 2024-08-28
629 Antibiotic-resistant bacteria in agricultural soil appraised against non-agricultural soil: case in one of the most agriculturally-active settings in West Cameroon
Kamgaing Nkamguia, L. K.; Youte, O. D.; Tamatcho Kweyang, B. P.; Kougang, E. G.; Well a Well a Koul, P. B.; Nana Feukeu, A.; Domngang Noche, C.; Fotsing Kwetche, P. R.
10.1101/2024.08.27.609998 — microbiology — Posted on 2024-08-28
630 Cytosolic sodium accumulation is a common danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation
Mangan, M. S. J.; Akbal, A.; Rivara, S.; Schroeder, A.; Horvath, G. L.; Walch, P.; Hegermann, J.; Kaiser, R.; Duthie, F.; Selkrig, J.; Jantsch, J.; Gerhard, R.; Wachten, D.; Latz, E.
10.1101/2024.03.26.586774 — immunology — Posted on 2024-08-28
631 Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing
Zhou, J.; Zhao, D.; Li, J.; Kong, D.; Li, X.; Zhang, R.; Liang, Y.; Gao, X.; Qian, Y.; Wang, D.; Chen, J.; Lai, L.; Han, Y.; Li, Z.
10.1101/2024.04.17.589933 — biochemistry — Posted on 2024-08-28
632 Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery
Adriaenssens, E.; Schaar, S.; Cooke, A. S. I.; Stuke, J. F. M.; Sawa-Makarska, J.; Nguyen, T. N.; Ren, X.; Schuschnig, M.; Romanov, J.; Khuu, G.; Lazarou, M.; Hummer, G.; Hurley, J. H.; Martens, S.
10.1101/2024.08.28.609967 — cell biology — Posted on 2024-08-28
633 High-throughput Image-based Clustering of CAR-T/Tumor Cocultures for Rapid and Facile Hit Identification
Xu, Z.; Liu, X.; Madden-Hennessey, K.; Urbani, J.; Nikkhoi, S. K.; Ramasubramanian, A.; G. Venugopal, K.; Zhao, Q.; L. Smith, E.; Fu, Y.
10.1101/2024.08.28.609577 — cell biology — Posted on 2024-08-28
636 Activational and organizational effects of sex hormones on hippocampal inhibitory neurons
Hernandez-Vivanco, A.; de la Vega Ruiz, R.; Montes-Mellado, A.; Azcoitia, I.; Mendez, P.
10.1101/2024.01.20.576232 — neuroscience — Posted on 2024-08-28
644 Pericytes require physiological oxygen tension to maintain phenotypic fidelity.
McErlain, T.; McCulla, E. C.; Glass, M. J.; Ziemer, L. E.; Branco, C. M.; Murgai, M.
10.1101/2024.08.28.606682 — cell biology — Posted on 2024-08-28
645 Single-molecule analysis of protein targeting from the endoplasmic reticulum to lipid droplets
Mizrak, A.; Kaestel-Hansen, J.; Matthias, J.; Harper, J. W.; Hatzakis, N. S.; Walther, T. C.; Farese, R. V.
10.1101/2024.08.27.610018 — cell biology — Posted on 2024-08-28
648 Artificial selection for adult predation survival impacts life history and morphology in guppies (Poecilia reticulata)
De Waele, H.; Vega-Trejo, R.; Vila-Pouca, C.; Noordenbos, J.; Phillips, E.; Pollux, B. J. A.; Kotrschal, A.
10.1101/2024.08.27.609842 — evolutionary biology — Posted on 2024-08-28
651 Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns
Baek, O.; Muk, T.; Wu, Z.; Ye, Y.; Khakimov, B.; Casano, A. M.; Gangadharan, B.; Bilic, I.; Brunse, A.; Sangild, P. T.; Nguyen, D. N.
10.1101/2023.09.11.557116 — immunology — Posted on 2024-08-28
652 Reconfiguration of Functional Brain Hierarchy in Schizophrenia
Acero, I.; Escrichs, A.; Dagnino, P. C. C.; Sanz Perl, Y.; Kringelbach, M. L.; Uhlhaas, P. J.; Deco, G.
10.1101/2024.08.27.608945 — neuroscience — Posted on 2024-08-28
654 Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis.
Higgins, B.; Simitsidellis, I.; Zheng, X.; Collins, F.; Homer, N.; Denham, S.; Simpson, J.; Millar, M.; Boswell, L.; Lee, H. Y.; Kim, Y. G.; Park, K. H.; Park, L. C.; Sweeney, P. J.; Feraille, G.; Taddei, A.; Chagras, D.; Alvarez, T.; Webster, S. P.; Horne, A. W.; Saunders, P. T.; Mole, D. J.
10.1101/2024.05.13.593856 — pathology — Posted on 2024-08-28
656 Modulation of antigen delivery and lymph node activation in non-human primates by saponin adjuvant SMNP
Yousefpour, P.; J. Zhang, Y.; Maiorino, L.; Melo, M. B.; Arainga Ramirez, M. A.; Kumarapperuma, S. C.; Xiao, P.; Silva, M.; Li, N.; Michaels, K. K.; Georgeson, E.; Eskandarzadeh, S.; Kubitz, M.; Groschel, B.; Qureshi, K.; Fontenot, J.; Hangartner, L.; Nedellec, R.; Love, J. C.; Burton, D. R.; Schief, W. R.; Villinger, F. J.; Irvine, D. J.
10.1101/2024.08.28.608716 — bioengineering — Posted on 2024-08-28
657 A Cryo-to-Liquid Phase Correlative Light Electron Microscopy Workflow for the Visualization of Biological Processes in Graphene Liquid Cells
Rutten, L.; Joosten, B.; Schaart, J. M.; Beer, M. d.; Roverts, R.; Graber, S.; Jahnen-Dechent, W.; Akiva, A.; Macias-Sanchez, E.; Sommerdijk, N.
10.1101/2023.05.08.539575 — biochemistry — Posted on 2024-08-28
661 Morphological Profiling Dataset of EU-OPENSCREEN Bioactive Compounds Over Multiple Imaging Sites and Cell Lines
Wolff, C.; Neuenschwander, M.; Beese, C. J.; Sitani, D.; Ramos, M. C.; Srovnalova, A.; Varela, M. J.; Polishchuk, P.; Skopelitou, K. E.; Skuta, C.; Stechmann, B.; Brea, J.; Clausen, M. H.; Dzubak, P.; Fernandez-Godino, R.; Genilloud, O.; Hajduch, M.; Loza, M. I.; Lehmann, M.; von Kries, J. P.; Sun, H.; Schmied, C.
10.1101/2024.08.27.609964 — cell biology — Posted on 2024-08-28
662 Versatile gamma-tubulin complexes contribute to the dynamic organization of MTOCs during Drosophila spermatogenesis
Alzyoud, E.; Nemeth, D.; Vedelek, V.; Szögi, T.; Toth, V. P.; Krecsmarik, M.; Abraham, E.; Lipinszki, Z.; Sinka, R.
10.1101/2024.03.20.585862 — cell biology — Posted on 2024-08-28
664 Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth
Maekiniemi, A.; Savakis, P.; Snoep, J. L.; Seiler, M.; van Rossum, K.; van Niekerk, D. D.; Zarnack, K.; Singer, R. H.; Tutucci, E.
10.1101/2022.03.01.481833 — molecular biology — Posted on 2024-08-28
666 BRAIN-METASTATIC MELANOMA MODELS UNCOVER IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY
Daugherty-Lopes, A.; Perez-Guijarro, E.; Gopalan, V.; Rappaport, J.; Chen, Q.; Huang, A.; Lam, K. C.; Chin, S.; Ebersole, J.; Wu, E.; Needle, G. A.; Church, I.; Kyriakopoulos, G.; Xie, S.; Zaho, Y.; Gruen, C.; Sassano, A.; Araya, R. E.; Thorkelsson, A.; Smith, C.; Lee, M. P.; Hannenhalli, S.; Day, C.-P.; Merlino, G.; Goldszmid, R. S.
10.1101/2024.08.26.609785 — immunology — Posted on 2024-08-28
668 Mu opioid receptors gate the locus coeruleus pain generator
Norris, M. R.; Kuo, C.-C.; Dunn, S. S.; Kim, J. R.; Becker, L. J.; Borges, G.; Thang, L. V.; Parker, K. E.; McCall, J. G.
10.1101/2023.10.20.562785 — neuroscience — Posted on 2024-08-28
669 Conditional Knockout of Striatal Gnal Produces Dystonia-like Motor Phenotypes
Chambers, N. E.; Hall, D.; Barsoum, S.; Miller, E.; Curry, T.; Kaplan, M.; Garan, S.; Gallardo, I.; Staab, R.; Nabert, D.; Hutchison, K.; Millett, M.; Moehle, M. S.
10.1101/2024.08.26.609754 — neuroscience — Posted on 2024-08-28
671 Machine learning and data-driven inverse modeling of metabolomics unveil key process of active aging
Li, J.; brenner, m.; pierides, i.; wessner, b.; franzke, b.; strasser, e. m.; Waldherr, S.; wagner, k. h.; Weckwerth, W.
10.1101/2024.08.27.609825 — systems biology — Posted on 2024-08-28
674 Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM
Macias, J. L. J.; Vaughn-Beaucaire, P.; Bharati, A.; Xu, Z.; Forrest, M.; Hong, J.; Sun, M.; Schmidt, A.; Clark, J.; Hawkins, W.; Mercado, N.; Real, J.; Huntington, K.; Zdioruk, M.; Nowicki, M. O.; Cho, C.-F.; Wu, B.; Li, W.; Logan, T.; Manz, K. E.; Pennell, K. D.; Fedeles, B. I.; Brodsky, A. S.; Lawler, S. E.
10.1101/2024.08.26.609797 — cancer biology — Posted on 2024-08-28
675 Dynamic positioning of a TFIIE-related winged-helix domain in RNA polymerase elongation complex III underpins its multi-functionality
Wu, J.-S.; Lin, Y.-C.; Wei, Y.-Y.; Lin, H.-H.; Liu, Y.-C.; Chang, J.-W.; Tu, I.-P.; Chen, H.-T.; Chang, W.-H.
10.1101/2024.08.27.609947 — biophysics — Posted on 2024-08-28
676 Multiple factors regulate i-motif and G-quadruplex structures in vitro: analysis of repeated and non-repeated polyG/polyC clusters by circular dichroism
Diggins, L.; Ross, D.; Bhanot, S.; Corallo, R.; Daley, R.; Patel, K.; Lewis, O.; Donahue, S.; Thaddeus, J.; Hiers, L.; Syed, C.; Eagerton, D.; Mohanty, B. K.
10.1101/2024.08.26.609788 — biophysics — Posted on 2024-08-28
679 Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle
Ghosh, R.; Chandra, G.; Verma, V.; Kaur, K.; Roychoudhury, A.; Mukherjee, S.; Chawla, A.; Mukherjee, K.
10.1101/2024.08.26.609607 — bioengineering — Posted on 2024-08-28
680 A multiomic atlas of human early skeletal development
To, K.; Fei, L.; Pett, J. P.; Roberts, K.; Polanski, K.; Li, T.; Yayon, N.; He, P.; Xu, C.; Cranley, J.; Li, R.; Kanemaru, K.; Huang, N.; Megas, S.; Richardson, L.; Kapuge, R.; Perera, S.; Tuck, E.; Wilbrey-Clark, A.; Mulas, I.; Memi, F.; Cakir, B.; Predeus, A. V.; Horsfall, D.; Murray, S.; Prete, M.; Mazin, P.; He, X.; Meyer, K. B.; Haniffa, M.; Barker, R. A.; Bayraktar, O.; Buckley, C. D.; Teichmann, S. A.
10.1101/2024.07.10.602965 — developmental biology — Posted on 2024-08-28
685 Diseased skin dermal proteomic profiles reflect shared extracellular matrix dysregulation patterns
Martins, L.; Malta, M. D.; Chaves, S.; Osorio, H.; Guttmann-Gruber, C.; Kocher, T.; Marques, A. P.
10.1101/2024.08.27.609987 — cell biology — Posted on 2024-08-28
687 Inpp5e is a Critical Regulator of Protein Transport to Photoreceptor Outer Segments
Gupta, M.; Lewis, T. R.; Stuck, M. W.; Spencer, W. J.; Klementieva, N. V.; Arshavsky, V. Y.; Pazour, G. J.
10.1101/2024.08.27.609873 — cell biology — Posted on 2024-08-28
688 Wound-initiated hair regeneration by adhesive and shrinkable materials
Kokabu, S.; Tsuji, K.; Washio, A.; Murata, K.; Nakatomi, M.; Ono, Y.; Kaminuma, O.; Matsubara, T.
10.1101/2024.08.27.610012 — cell biology — Posted on 2024-08-28
689 HIRA-dependent provision of histone H3.3 in active chromatin ensures genome compartmentalisation
Karagyozova, T.; Gatto, A.; Forest, A.; Quivy, J.-P.; Marti-Renom, M. A.; Mirny, L.; Almouzni, G.
10.1101/2024.08.27.609896 — cell biology — Posted on 2024-08-28
690 NEMF-mediated CAT-tailing defines distinct branches of translocation-associated quality control
Ennis, A.; Wang, L.; Wang, X.; Yu, C.; Saidi, L.; Xu, Y.; Yun, S.; Huang, L.; Ye, Y.
10.1101/2024.08.27.610005 — cell biology — Posted on 2024-08-28
692 Modeling Decision-Making Under Uncertainty with Qualitative Outcomes
Korem, N.; Duek, O.; Jia, R.; Wertheimer, E.; Metviner, S.; Grubb, M.; Levy, I.
10.1101/2024.08.27.609831 — neuroscience — Posted on 2024-08-28
694 Near-infrared MINFLUX imaging enabled by suppression of fluorophore blinking
Srambickal, C. V.; Esmaeeli, H.; Piguet, J.; Reinkensmeier, L.; Siegmund, R.; Bates, M.; Egner, A.; Widengren, J.
10.1101/2024.08.27.609859 — biophysics — Posted on 2024-08-28
698 3D-Printable Non-invasive Head Immobilization System for Non-Human Primates
Shahbazi, E.; Nguyen, D.; Swedan, T.; Ma, T.; Lafer-Sousa, R.; Dinh, A.; Azadi, R.; Ryan, A.; Afraz, A.
10.1101/2024.01.02.573832 — physiology — Posted on 2024-08-28
701 Hypothalamic representation of the imminence of predator threat detected by the vomeronasal organ in mice
Nguyen, Q. A. T.; Rocha, A.; Chhor, R.; Yamashita, Y.; Stadler, C.; Pontrello, C.; Yang, H.; Haga-Yamanaka, S.
10.1101/2023.09.27.559655 — neuroscience — Posted on 2024-08-28
703 Senescent cell-derived extracellular vesicles inhibit cancer recurrence by coordinating immune surveillance
Ziglari, T.; Calistri, N.; Finan, J. M.; Derrick, D.; Nakayasu, E. S.; Burnet, M.; Kyle, J. E.; Hoare, M. W.; Heiser, L.; Pucci, F.
10.1101/2022.06.30.498366 — cancer biology — Posted on 2024-08-28
705 Genomes of nitrogen-fixing eukaryotes reveal a non-canonical model of organellogenesis
Frail, S.; Steele-Ogus, M.; Doenier, J.; Moulin, S. L. Y.; Braukmann, T.; Xu, S.; Yeh, E.
10.1101/2024.08.27.609708 — evolutionary biology — Posted on 2024-08-28
707 PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum
Chahine, Z. M.; Gupta, M.; Lenz, T.; Hollin, T.; Abel, S.; Banks, C.; Saraf, A.; Prudhomme, J.; Bhanvadia, S.; Florens, L.; Le Roch, K. G.
10.1101/2023.09.11.557253 — microbiology — Posted on 2024-08-28
708 Foundation model of neural activity predicts response to new stimulus types and anatomy
Wang, E. Y.; Fahey, P. G.; Ding, Z.; Papadopoulos, S.; Ponder, K.; Weis, M.; Chang, A.; Muhammad, T.; Patel, S.; Ding, Z.; Tran, D. T.; Fu, J.; Schneider-Mizell, C. M.; Reid, R. C.; Collman, F.; da Costa, N. M.; Franke, K.; Ecker, A. S.; Reimer, J.; Pitkow, X.; Sinz, F. H.; Tolias, A. S.
10.1101/2023.03.21.533548 — neuroscience — Posted on 2024-08-28
711 mosGraphGen: a novel tool to generate multi-omics signaling graphs to facilitate integrative and interpretable graph AI model development
Zhang, H.; Cao, D.; Chen, Z.; Zhang, Z.; Chen, Y.; Sessions, C.; Cruchaga, C.; Payne, P. R.; Li, G.; Province, M.; Li, F.
10.1101/2024.05.15.594360 — systems biology — Posted on 2024-08-28
714 Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer
DeAngelo, S. L.; Zhao, L.; Dziechciarz, S.; Shin, M.; Solanki, S.; Balia, A.; El-Derany, M. O.; Castillo, C.; Qin, Y.; Das, N. K.; Bell, H. N.; Paulo, J. A.; Zhang, Y.; Rossiter, N. J.; McCulla, E. C.; He, J.; Talukder, I.; Ng, B. W.-L.; Schafer, Z. T.; Neamati, N.; Mancias, J. D.; Koutmos, M.; Shah, Y. M.
10.1101/2024.03.29.587381 — cancer biology — Posted on 2024-08-28
715 The inhibition of three distinct signaling pathways eliminates the oncogenic Tribbles homolog 2 from melanoma cells
Mayoral-Varo, V.; Orea-Soufi, A.; Jimenez, L.; Santos, B.; Serrao, G.; Jociles, M.; Obeso, S.; Ferreira, B.; Link, W.
10.1101/2024.07.17.603886 — cancer biology — Posted on 2024-08-28
718 Alligamycin A, an unprecedented antifungal β-lactone spiroketal macrolide from Streptomyces iranensis
Yang, Z.; Qiao, Y.; Strobech, E.; Morth, J. P.; Walther, G.; Jorgensen, T. S.; Peschel, G.; Rosenbaum, M. A.; Previtali, V.; Clausen, M. H.; Lukassen, M. V.; Gotfredsen, C. H.; Kurzai, O.; Weber, T.; Ding, L.
10.1101/2024.04.17.589928 — biochemistry — Posted on 2024-08-27
719 DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids
Dearlove, E. L.; Chatrin, C.; Buetow, L.; Ahmed, S. F.; Schmidt, T.; Bushell, M.; Smith, B. O.; Huang, D. T.
10.1101/2024.04.02.587769 — biochemistry — Posted on 2024-08-28
723 Using artificial intelligence to document the hidden RNA virosphere
Hou, X.; He, Y.; Fang, P.; Mei, S.-Q.; Xu, Z.; Wu, W.-C.; Tian, J.-H.; Zhang, S.; Zeng, Z.-Y.; Gou, Q.-Y.; Xin, G.-Y.; Le, S.-J.; Xia, Y.-Y.; Zhou, Y.-L.; Hui, F.-M.; Pan, Y.-F.; Eden, J.-S.; Yang, Z.-H.; Han, C.; Shu, Y.-L.; Guo, D.; Li, J.; Holmes, E. C.; Li, Z.-R.; Shi, M.
10.1101/2023.04.18.537342 — microbiology — Posted on 2024-08-27
725 Vascular FLRT2 regulates venous-mediated angiogenic expansion and CNS barriergenesis
Llao-Cid, C.; Peguera, B.; Kobialka, P.; Decker, L.; Vogenstahl, J.; Alivodej, N.; Srivastava, S.; Jin, J.; Kirchmaier, B.; Milla, C.; Schlierbach, H.; Schaenzer, A.; Acker, T.; Segarra, M.; Acker-Palmer, A.
10.1101/2024.08.27.609862 — neuroscience — Posted on 2024-08-27
726 Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation
Mathieu, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.
10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-08-27
727 Dissociating External and Internal Attentional Selection
Arora, K.; Gayet, S.; Kenemans, J. L.; Van der Stigchel, S.; Chota, S.
10.1101/2024.08.27.609883 — neuroscience — Posted on 2024-08-27
729 Type 1 interferon perturbates clonal competition by reshaping human blood development
Lama, C.; Isakov, D.; Rosenberg, S.; Quijada-Alamo, M.; Saurty-Seerunghen, M. S.; Moein, S.; Abera, T.-A.; Sakaguchi, O.; Totwani, M.; Freed, G.; Poon, C.-L.; Parghi, N.; Kubas-Meyer, A.; Xie, A. X.; Omar, M.; Choi, D.; Castillo-Tokumori, F.; Abu-Zeinah, G.; Dillard, A.; Omans, N. D.; Dusaj, N. N.; Chamely, P.; Mimitou, E.; Smibert, P.; Kosiorek, H. E.; Dueck, A. C.; Weinberg, R.; Chaligne, R.; Marcellino, B.; Marchionni, L.; Patel, S.; Simonson, P. D.; Landau, D. A.; Wagenblast, E.; Hoffman, R.; Nam, A. S.
10.1101/2022.09.28.509751 — cancer biology — Posted on 2024-08-27
731 Kinome screening identifies integrated stress response kinase EIF2AK1 / HRI as a negative regulator of PINK1 mitophagy signaling
Singh, P.; Agarwal, S.; Volpi, I.; Wilhelm, L. P.; Becchi, G.; Keenlyside, A.; Macartney, T.; Toth, R.; Rousseau, A.; Masson, G.; Ganley, I. G.; Muqit, M. M. K.
10.1101/2023.03.20.533516 — biochemistry — Posted on 2024-08-27
732 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Patel, S. P.; Munugala, C.; Bloom, J. S.; Kruglyak, L.
10.1101/2023.12.07.570640 — genetics — Posted on 2024-08-27
734 IDENTIFICATION OF AN EARLY SUBSET OF CEREBELLAR NUCLEI NEURONS IN MICE
Rahimi-Balaei, M.; Amiri, S.; Lamonerie, T.; Wu, S.-R.; Zoghbi, H. Y.; Consalez, G. G.; Goldowitz, D.; Marzban, H.
10.1101/212571 — developmental biology — Posted on 2024-08-27
735 Morphological Profiling Dataset of EU-OPENSCREEN Bioactive Compounds Over Multiple Imaging Sites and Cell Lines
Wolff, C.; Neuenschwander, M.; Beese, C. J.; Sitani, D.; Ramos, M. C.; Srovnalova, A.; Varela, M. J.; Polishchuk, P.; Skopelitou, K. E.; Skuta, C.; Stechmann, B.; Brea, J.; Clausen, M. H.; Dzubak, P.; Fernandez-Godino, R.; Genilloud, O.; Hajduch, M.; Loza, M. I.; Lehmann, M.; von Kries, J. P.; Sun, H.; Schmied, C.
10.1101/2024.08.27.609964 — cell biology — Posted on 2024-08-27
736 Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress
Dar, S. A.; Malla, S.; Martinek, V.; Payea, M. J.; Lee, C. T.-Y.; Martin, J.; Khandeshi, A. J.; Martindale, J. L.; Belair, C.; Maragkakis, M.
10.1101/2023.08.31.555629 — cell biology — Posted on 2024-08-27
737 Interplay Between FoxM1 and Dab2 Promotes Endothelial Cell Responses in Diabetic Wound Healing
Bhattacharjee, S.; Gao, J.; Lu, Y. W.; Eisa-Beygi, S.; Wu, H.; Li, K. S.; Birsner, A. E.; Wong, S.; Song, Y.; Shyy, J. Y.-J.; Cowan, D. B.; Wei, W.; Aikawa, M.; Shi, J.; Chen, H.
10.1101/2024.02.07.579019 — cell biology — Posted on 2024-08-27
740 Super-Resolution Simplified: Sub-10nm Imaging Over Large Areas and Deep Penetration via SDC-OPR and DNA-PAINT
Zaza, C.; Joseph, M. D.; Dalby, O. P. L.; Walther, R. F.; Kolataj, K.; Chiarelli, G.; Pichaud, F.; Acuna, G. P.; Simoncelli, S.
10.1101/2024.08.26.609760 — biophysics — Posted on 2024-08-27
742 Coenzyme-Protein Interactions since Early Life
Sanchez Rocha, A. C.; Makarov, M.; Pravda, L.; Novotny, M.; Hlouchova, K.
10.1101/2023.10.28.563965 — bioinformatics — Posted on 2024-08-27
744 Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-dispersal activity against Vibrio Polysaccharide (VPS)
Weeresekera, R.; Moreau, A.; Huang, X.; Nam, K.-M.; Hinbest, A.; Huynh, Y.; Liu, X.; Ashwood, C.; Pepi, L. E.; Cegelski, L.; Yan, J.; Olson, R.
10.1101/2024.08.27.609776 — biochemistry — Posted on 2024-08-27
745 Multiple polyploidizations in Arabidopsis lyrata stabilized by long-range adaptive introgression across Eurasia
Scott, A. D.; Kolesnikova, U. K.; Glushkevich, A.; Steinmann, L.; Tikhomirov, N.; Pfordt, U.; Bohutinska, M.; Burns, R.; Seregin, A. P.; Kolar, F.; Schmickl, R.; Novikova, P. Y.
10.1101/2024.08.27.609292 — genomics — Posted on 2024-08-27
746 BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD
Tran, U.; Streets, A. J.; Smith, D.; Decker, E.; Kirschfink, A.; Izem, L.; Hassey, J.; Ruthland, B.; Valluru, M. K.; Bräsen, J. H.; Ott, E.; Epting, D.; Eisenberger, T.; Ong, A. C.; Bergmann, C.; Wessely, O.
10.1101/2024.08.27.608867 — genetics — Posted on 2024-08-27
751 Dimensionality reduction simplifies synaptic partner matching in an olfactory circuit
Lyu, C.; Li, Z.; Xu, C.; Wong, K. K. L.; Luginbuhl, D. J.; McLaughlin, C. N.; Xie, Q.; Li, T.; Li, H.; Luo, L.
10.1101/2024.08.27.609939 — developmental biology — Posted on 2024-08-27
752 Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis
Wan, Y.; El Kholtei, J.; Jenie, I.; Colomer-Rosell, M.; Liu, J.; Acedo, J. N.; Du, L. Y.; Codina-Tobias, M.; Wang, M.; Sawh, A.; Lin, E.; Chuang, T.-H.; Mango, S. E.; Yu, G.; Bintu, B.; Schier, A. F.
10.1101/2024.08.27.609868 — developmental biology — Posted on 2024-08-27
753 Dissecting the regulatory logic of specification and differentiation during vertebrate embryogenesis
Liu, J.; Castillo-Hair, S. M.; Du, L. Y.; Wang, Y.; Carte, A. N.; Colomer-Rosell, M.; Yin, C.; Seelig, G.; Schier, A. F.
10.1101/2024.08.27.609971 — developmental biology — Posted on 2024-08-27
755 A novel chemogenomic screening platform for scalable antimalarial drug target identification
Bower-Lepts, C. A.; Rawat, M.; Keith, W. C.; Girling, G.; Luth, M. R.; Carolino, K.; Boroviak, K.; Coyle, R.; Schwach, F.; Smidt, C.; Bushell, E.; Moliner-Cubel, S.; Gomez-Lorenzo, M. D. G.; Gamo, F.-J.; Winzeler, E. A.; Billker, O.; Lee, M. C.; Rayner, J. C.
10.1101/2024.08.27.609875 — microbiology — Posted on 2024-08-27
757 Tracing active bugs in microbial communities by BONCAT and click chemistry-based enrichment of newly synthesised proteins
Hellwig, P.; Kautzner, D.; Heyer, R.; Dittrich, A.; Wibberg, D.; Busche, T.; Winkler, A.; Reichl, U.; Benndorf, D.
10.1101/2024.08.27.609880 — microbiology — Posted on 2024-08-27
758 Posteromedial cortical networks encode visuomotor prediction errors.
Takeuchi, R. F.; Sato, A. Y.; Ito, K. N.; Yokoyama, H.; Miyata, R.; Ueda, R.; Kitajima, K.; Kamaguchi, R.; Suzuki, T.; Isobe, K.; Honda, N.; Osakada, F.
10.1101/2022.08.16.504075 — neuroscience — Posted on 2024-08-27
759 Exosomes can modulate the early hyperexcitability in cortical neurons with ASD-associated Shank3 mutation.
Choudhary, A.; Rosh, I.; Hussein, Y.; Shemen, A.; Rike, W. A.; Zinger, A.; Offen, D.; Stern, S.
10.1101/2024.08.27.609917 — neuroscience — Posted on 2024-08-27
760 Therapeutic suppression of Tubb4a rescues H-ABC leukodystrophy
Sase, S.; Hacker, J. L.; Napit, P. R.; Woidill, S.; Bhagavatula, A.; Alessandro, A. D.; Almad, A.; Takanohashi, A.; Padiath, Q.; Marsh, E. D.; Vanderver, A.
10.1101/2024.08.27.609903 — neuroscience — Posted on 2024-08-27
762 NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks
Koonce, N. L.; Emerson, S. E.; Bhaskar, D.; Kuchroo, M.; Moyle, M. W.; Arroyo-Morales, P.; Martinez, N. V.; Krishnaswamy, S.; Mohler, W.; Colon-Ramos, D.
10.1101/2024.08.27.609993 — neuroscience — Posted on 2024-08-27
763 Cargo quantification of functionalized DNA origami for therapeutic application
Young, O.; Dembele, H.; Rajwar, A.; Kwon, I. C.; Ryu, J. H.; Shih, W.; Zeng, Y.
10.1101/2024.08.27.609963 — synthetic biology — Posted on 2024-08-27
764 Comparative transcriptomics in ferns reveals key innovations and divergent evolution of secondary cell wall
Ali, Z.; Tan, Q. W.; Lim, P. K.; Chen, H.; Pfeifer, L.; Julca, I.; Lee, J.; Vinter, F.; Layens, A.; Alvarado, C.; de Vries, J.; de Vries, S.; Classen, B.; Mizrachi, E.; Motawie, M.; Joergensen, B.; Ulvskov, P.; Koh, T. S.; Chin, L. l.; van de Peer, Y.; Ho, B. C.; Sibout, R.; Mutwil, M.
10.1101/2024.08.27.609851 — plant biology — Posted on 2024-08-27
765 The role of phosphorylation and dephosphorylation in the regulation of Rubisco activase
Bhatnagar, N.; Chung, S. S.; Hodge, J.; Boyd, R.; Kim, S. Y.; Sands, M.; Leakey, A.; Ort, D. R.; Burgess, S. J.
10.1101/2024.08.27.609719 — plant biology — Posted on 2024-08-27
766 Hemi Manganese Exchangers 1 and 2 enable manganese import at the plasma membrane in cyanobacteria
Reis, M.; Brandenburg, F.; Knopp, M.; Flachbart, S.; Braeutigam, A.; Metzger, S.; Gould, S. B.; Eisenhut, M.
10.1101/2023.02.16.528846 — plant biology — Posted on 2024-08-27
768 Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure
Lang, D.; Ni, H.; Medvedev, R.; Liu, F. V.; Alvarez-Baron, C. P.; Tyan, L.; Turner, D.; Warden, A.; Morotti, S.; Schrauth, T.; Chanda, B.; Kamp, T. J.; Robertson, G.; Grandi, E.; Glukhov, A. V.
10.1101/2024.04.14.589457 — physiology — Posted on 2024-08-27
770 Mitochondrial sites of contact with the nucleus aid in chemotherapy evasion of glioblastoma cells
Strobbe, D.; Bueno, M.; De Vitis, C.; Hassan, S.; Faccenda, D.; Bruqi, K.; Romano, E.; Pedace, L.; Iurchenko, A. A.; Dhoot, G. K.; Bistrot, I. J.; Klamt, F.; Lenz, L. S.; Chiela, E. C. F.; Urso, P. I. D.; Lally, I.; Miele, E.; Falasca, L.; Nikolaev, S.; Mancini, R.; Roncaroli, F.; Lenz, G.; Campanella, M.
10.1101/2024.08.27.608373 — cancer biology — Posted on 2024-08-27
771 Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment
Mukherjee, A. K.; Dutta, S.; Singh, A.; Sharma, S.; Roy, S. S.; Sengupta, A.; Chatterjee, M.; Vinayagamurthy, S.; Bagri, S.; Khanna, D.; Verma, M.; Soni, D.; Budharaja, A.; Bhisade, S. K.; anand, V.; Perwez, A.; George, N.; Faruq, M.; Gupta, I.; Sabarinathan, R.; Chowdhury, S.
10.1101/2021.12.07.471419 — cancer biology — Posted on 2024-08-27
773 EML4-ALK variant-specific genetic interactions shape lung tumorigenesis
Diaz-Jimenez, A.; Shuldiner, E. G.; Somogyi, K.; Gonzalez, O.; Akkas, F.; Murray, C. W.; Andrejka, L.; Tsai, M. K.; Brors, B.; Sivakumar, S.; Sisoudiya, S. D.; Sokol, E. S.; Petrov, D.; Winslow, M. M.; Sotillo, R.
10.1101/2024.08.26.609730 — cancer biology — Posted on 2024-08-27
774 Engineering of ATP synthase for enhancement of proton-to-ATP ratio
Ueno, H.; Yasuda, K.; Hamaguchi-Suzuki, N.; Marui, R.; Adachi, N.; Senda, T.; Murata, T.; Noji, H.
10.1101/2024.08.27.609901 — biophysics — Posted on 2024-08-27
775 An alternative mechanism for activation of innate immune signaling by MDA5
Quack, S.; Maity, S.; America, P. P. B.; Klein, M.; Herrero del Valle, A.; Singh, R.; Smitskamp, Q.; Papini, F. S.; Broedersz, C.; Roos, W.; Modis, Y.; Dulin, D.
10.1101/2024.08.27.609867 — biophysics — Posted on 2024-08-27
776 QuICSeedR: An R package for analyzing fluorophore-assisted seed amplification assay data
Li, M.; Bryant, D. N.; Gresch, S.; Milstein, M.; Christenson, P. R.; Lichtenberg, S. S.; Larsen, P. A.; Oh, S.-H.
10.1101/2024.08.27.609919 — bioinformatics — Posted on 2024-08-27
779 FibrilPaint targets amyloid fibrils for ubiquitination
Dekker, F. A.; Aragnones Pedrola, J.; Poza-Rodriguez, A.; Mayer, G.; Singh, S.; Heesink, G.; Claessens, M. M. A. E.; Friedler, A.; Rudiger, S. G. D.
10.1101/2024.08.27.609886 — biochemistry — Posted on 2024-08-27
781 Onset of infectiousness explains differences in transmissibility across Mycobacterium tuberculosis lineages
Windels, E. M.; Agüi, C. V.; de Jong, B. C.; Meehan, C. J.; Loiseau, C.; Goig, G. A.; Zwyer, M.; Borrell, S.; Brites, D.; Gagneux, S.; Stadler, T.
10.1101/2024.08.27.609909 — genomics — Posted on 2024-08-27
782 Temporally discordant chromatin accessibility and DNA demethylation define short and long-term enhancer regulation during cell fate specification
Guerin, L.; Scott, T. J.; Yap, J. A.; Johansson, A.; Puddu, F.; Charlesworth, T.; Simmons, A. J.; Yang, Y.; Lau, K.; Ihrie, R. A.; Hodges, E.
10.1101/2024.08.27.609789 — genomics — Posted on 2024-08-27
785 Gene expression and chromatin accessibility comparison in iPSC-derived microglia in African, European, and Amerindian genomes in Alzheimer's patients and controls.
Moura, S.; Nasciben, L. B.; Ramirez, A. M.; Coombs, L.; Rivero, J.; Van Booven, D. J.; DeRosa, B. A.; Hamilton-Nelson, K. L.; Whitehead, P. L.; Adams, L. D.; Starks, T. D.; Mena, P. R.; Illanes-Manrique, M.; Tejada, S.; Byrd, G. S.; Cornejo-Olivas, M. R.; Feliciano-Astacio, B. E.; Nuytemans, K.; Wang, L.; Pericak-Vance, M. A.; Dykxhoorn, D. M.; Rajabli, F.; Griswold, A. J.; Young, J. I.; Vance, J. M.
10.1101/2024.08.27.609943 — genomics — Posted on 2024-08-27
787 Analysing drivers of worldwide tidal wetland change
Perrodin, L.; Otero, A. N.; Toor, M.; Canto, R.; Becker, M.; Dong, Y.; Worthington, T. A.; Murray, N. J.
10.1101/2024.08.27.609936 — ecology — Posted on 2024-08-27
791 The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC
Richard, J.; Grunst, M. W.; Niu, L.; Diaz-Salinas, M. A.; Tolbert, W. D.; Marchitto, L.; Zhou, F.; Bourassa, C.; Yang, D.; Chiu, T.-J.; Chen, H.-C.; Benlarbi, M.; Beaudoin-Bussieres, G.; Gottumukkala, S.; Li, W.; Dionne, K.; Belanger, E.; Chatterjee, D.; Medjahed, H.; Hendrickson, W. A.; Sodroski, J.; Lang, Z. C.; Morton, A. J.; Huang, R. K.; Matthies, D.; Smith, A. B.; Mothes, W.; Munro, J.; Pazgier, M.; Finzi, A.
10.1101/2024.08.27.609961 — microbiology — Posted on 2024-08-27
792 Optimization of screening methods leads to the discovery of new viruses in black soldier flies (Hermetia illucens)
Pienaar, R. D.; Herrero, S.; Cerqueira de Araujo, A.; Krupa, F.; Abd-Alla, A. M. M.; Herniou, E. A.
10.1101/2024.08.27.609913 — microbiology — Posted on 2024-08-27
794 Early steps of the biosynthesis of the anticancer antibiotic pleurotin
Weaver, J. A.; Alkhder, D.; Prasongpholchai, P.; Tadesse, M. D.; de los Santos, E. L. C.; Song, L.; Corre, C.; Alberti, F.
10.1101/2024.08.27.609176 — microbiology — Posted on 2024-08-27
795 HIF-alpha signaling mediates the macrophage inflammatory response during Leishmania major infection
Fry, L. G.; Washam, C. L.; Roys, H.; Bowlin, A. K.; Venugopal, G.; Bird, J. T.; Byrum, S. D.; Weinkopff, T.
10.1101/2024.08.27.605844 — microbiology — Posted on 2024-08-27
798 Microbiome diversity, intra-mucosal bacteria and immune integration within normal and asthmatic airway mucosa
Moffatt, M. F.; Nishimura, T.; Cox, M. J.; McBrien, C. N.; Burke, C.; Cuthbertson, L.; Lewis, K. E.; Attanoos, R.; Davies, G. A.; Chung, K. F.; Robertus, J. L.; Ish-Horowicz, J. S.; Carroll, O.; Bozeman, J. M.; McGowan, A.; Hopkin, J. M.; Lathrop, G. M.; Riazalhosseini, Y.; Cookson, W. O.
10.1101/2024.08.27.609874 — microbiology — Posted on 2024-08-27
801 Development of a highly-sensitive method to detect the carriage of carbapenem-resistant Pseudomonas aeruginosa in humans
Shahab, S. N.; van Veen, A.; Kempenaars, N.; Rijfkogel, A.; Schmitt, H.; Saharman, Y. R.; Vos, M. C.; Karuniawati, A.; Severin, J. A.
10.1101/2024.08.27.609846 — microbiology — Posted on 2024-08-27
802 Distinct immune profiles in children living with HIV based on timing and duration of suppressive antiretroviral treatment
Lee, M. J.; Litchford, M. L.; Vendrame, E.; Vergara, R.; Ranganath, T.; Fish, C. S.; Chebet, D.; Langat, A.; Mburu, C.; Neary, J.; Benki, S. F.; Wamalwa, D.; John-Stewart, G.; Lehman, D.; Blish, C. A.
10.1101/2024.08.27.609833 — immunology — Posted on 2024-08-27
803 Regulation of Leucine-Rich Repeat Kinase 2 by inflammation and IL-4
Dikovskaya, D.; Pemberton, R.; Taylor, M.; Tasegian, A.; Zenevicuite, K.; Sammler, E.; Howden, A. J.; Alessi, D. R.; Swamy, M.
10.1101/2024.04.29.591170 — immunology — Posted on 2024-08-27
804 A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit
SUN, J.; ROJO-CORTES, F. R.; ULIAN-BENITEZ, S.; FORERO, M. G.; LI, G.; SINGH, D.; WANG, X.; CACHERO, S.; MOREIRA, M.; KAVANAGH, D.; JEFFERIS, G. S. X. E.; CROSET, V.; HIDALGO, A.
10.1101/2023.01.04.522695 — neuroscience — Posted on 2024-08-27
805 The evolution of wasp mimicry and biogeography in the genus Temnostoma (Diptera: Syrphidae)
Hadrava, J.; Klecka, J.; Moran, K.; Kleckova, I.; Kelso, S.; Etzbauer, C.; Skevington, J. H.; Mengual, X.
10.1101/2024.08.27.609869 — zoology — Posted on 2024-08-27
806 A fluorescent probe enables the discovery of improved antagonists targeting the intracellular allosteric site of the chemokine receptor CCR7
Wurnig, S. L.; Huber, M. E.; Weiler, C.; Baltrukevich, H.; Merten, N.; Stoetzel, I.; Chang, Y.; Klammer, R.; Baumjohann, D.; Kiermaier, E.; Kolb, P.; Kostenis, E.; Schiedel, M.; Hansen, F. K.
10.1101/2024.08.27.607356 — pharmacology and toxicology — Posted on 2024-08-27
807 Synchronous L1 retrotransposition events promote chromosomal crossover early in human tumorigenesis
Zumalave, S.; Santamarina, M.; Espasandin, N. P.; Garcia-Souto, D.; Temes, J.; Baker, T. M.; Valtierra, A. P.; Otero, I.; Rodriguez-Castro, J.; Oitaben, A.; Alvarez, E. G.; Otero, P.; Diaz-Arias, I.; Martinez-Fernandez, M.; Van Loo, P.; Cristofari, G.; Rodriguez-Martin, B.; Tubio, J. M.
10.1101/2024.08.27.596794 — cancer biology — Posted on 2024-08-27
809 Characterizing features affecting local ancestry inference performance in admixed populations
Honorato-Mauer, J.; Shah, N. N.; Maihofer, A. X.; Zai, C. C.; Belangero, S.; Nievergelt, C. M.; Psychiatric Genomics Consortium for PTSD Ancestry Working Group, ; Santoro, M.; Atkinson, E. G.
10.1101/2024.08.26.609770 — genomics — Posted on 2024-08-27
810 Functional and evolutionary constraints of wtf killer meiotic drivers
Srinivasa, A. N.; Campbell, S.; Venkatesan, S.; Nuckolls, N. L.; Lange, J. J.; Halfmann, R.; Zanders, S. E.
10.1101/2024.08.27.609905 — genetics — Posted on 2024-08-27
811 Genomes of nitrogen-fixing eukaryotes reveal a non-canonical model of organellogenesis
Frail, S.; Steele-Ogus, M.; Doenier, J.; Moulin, S. L. Y.; Braukmann, T.; Xu, S.; Yeh, E.
10.1101/2024.08.27.609708 — evolutionary biology — Posted on 2024-08-27
815 Behavioral screening defines three molecular Parkinsonism subgroups in Drosophila
Kaempf, N.; Valadas, J. D. S.; Robberechts, P.; Schoovaerts, N.; Praschberger, R.; Ortega, A.; Kilic, A.; Chabot, D.; Pech, U.; Kuenen, S.; Vilain, S.; Baz, E.-S.; Singh, J.; Davis, J.; Liu, S.; Verstreken, P.
10.1101/2024.08.27.609924 — neuroscience — Posted on 2024-08-27
816 A robust evaluation of TDP-43, poly GP, cellular pathology, and behavior in a AAV-C9ORF72 (G4C2)66 mouse model
Thompson, E. G.; Spead, O. M.; Akerman, S. C.; Curcio, C.; Zaepfel, B. L.; Kent, E.; Philips, T.; Vijayakumar, B. G.; Zacco, A.; Zhou, W.; Nagappan, G.; Rothstein, J. D.
10.1101/2024.08.27.607409 — neuroscience — Posted on 2024-08-27
817 Birth order specified recruitment of motor circuits during spontaneous neural activity in zebrafish embryo
Abi Younes, M.; Rima, M.; Coutanceau, J.-p.; Peysson, N.; Hoseinkhani, F.; Rodrigues, E.; Bullier, E.; Legendre, P.; Mangin, J.-M.; Hong, E.
10.1101/2024.08.27.609675 — neuroscience — Posted on 2024-08-27
821 YOLO-Behaviour: A simple, flexible framework to automatically quantify animal behaviours from videos
Chan, A. H. H.; Putra, P.; Schupp, H.; Köchling, J.; Strassheim, J.; Renner, B.; Schroeder, J.; Pearse, W. D.; Nakagawa, S.; Burke, T.; Griesser, M.; Meltzer, A.; Lubrano, S.; Kano, F.
10.1101/2024.08.26.609387 — animal behavior and cognition — Posted on 2024-08-27
822 Transcripts and genomic intervals associated with variation in metabolite abundance in maize leaves under field conditions
Mathivanan, R. K.; Pedersen, C.; Turkus, J.; Shrestha, N.; Torres-Rodriguez, J. V.; Mural, R. V.; Obata, T.; Schnable, J. C.
10.1101/2024.08.26.609532 — genomics — Posted on 2024-08-27
823 Targeting Liver Epsins Ameliorates Dyslipidemia in Atherosclerosis
Zhu, B.; Gupta, K.; Cui, K.; Wang, B.; Malovichko, M. V.; Han, X.; Li, K. S.; Wu, H.; Arulsamy, K. S.; Singh, B.; Gao, J.; Wong, S.; Cowan, D. B.; WANG, D.-Z.; Biddinger, S.; Srivastava, S.; Shi, J.; Chen, K.; Chen, H.
10.1101/2024.08.26.609742 — cell biology — Posted on 2024-08-27
824 Mining Yeast Diversity Unveils Novel Targets for Improved Heterologous Laccase Production in Saccharomyces cerevisiae
Wong, R. W. K.; Foo, M.; Lay, J. R. S.; Wai, T. L. T.; Moore, J.; Dutreux, F.; Molzahn, C.; Nislow, C.; Measday, V.; Schacherer, J.; Mayor, T.
10.1101/2024.08.26.609787 — molecular biology — Posted on 2024-08-27
829 Center-surround inhibition by expectation: a neuro-computational account
Huang, L.; Shen, S.; Sun, Y.; Ou, S.; Zhang, R.; de Lange, F. P.; ZHANG, X.
10.1101/2024.08.26.609781 — neuroscience — Posted on 2024-08-27
830 Maternal progesterone and adipose mPRε in pregnancy regulate the embryonic nutritional state
Watanabe, K.; Yamano, M.; Miyamoto, J.; Ohue-Kitano, R.; Masujima, Y.; Sasahara, D.; Mouri, Y.; Kono, N.; Inuki, S.; Osakada, F.; Nagaoka, K.; Aoki, J.; Sugiura, Y.; Ohno, H.; Kondoh, E.; Kimura, I.
10.1101/2024.08.26.609823 — physiology — Posted on 2024-08-27
831 Vapor-based Fixation of Pulmonary Tissue in its Physiological State: A Novel Approach to Histological Validation of Ultra High Resolution Phase Contrast CT in Human Sized Lungs
Dullin, C.; Reiser, J.; Wagner, W.; Longo, E.; Prasek, M.; Contillo, A.; Sodini, N.; Dreossi, D.; Confalonieri, P.; Salton, F.; Confalonieri, M.; Baratella, E.; Cova, M.; Benke, C.; Sagar, M. M. R.; D'Amico, L.; Albers, J.; Svetlove, A.; Flisikowska, T.; Flisikowski, K.; Wielpuetz, M. O.; Biederer, J.; Kauczor, H.-U.; Zanconati, F.; Tromba, G.
10.1101/2024.08.26.609748 — pathology — Posted on 2024-08-27
832 H3K27M diffuse midline glioma is homologous recombination defective and sensitized to radiotherapy and NK cell-mediated antitumor immunity by PARP inhibition
Guo, Y.; Li, Z.; Parsels, L. A.; Wang, Z.; Parsels, J. D.; Dalvi, A.; The, S.; Hu, N.; Valvo, V. M.; Doherty, R.; Peterson, E.; Wang, X.; Venkataraman, S.; Agnihotri, S.; Venneti, S.; Wahl, D.; Green, M. D.; Lawrence, T. S.; Koschmann, C.; Morgan, M. A.; Zhang, Q.
10.1101/2024.08.26.609803 — cancer biology — Posted on 2024-08-27
833 Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma
Braun, S.; Bolivar, P.; Oudenaarden, C.; Sjolund, J.; Bocci, M.; Harbst, K.; Talkhoncheh, M. S.; Phung, B.; Cordero, E.; Rosberg, R.; Johansson, E.; Jonsson, G.; Pietras, A.; Pietras, K.
10.1101/2024.08.26.609765 — cancer biology — Posted on 2024-08-27
837 pyVIPER: A fast and scalable Python package for rank-based enrichment analysis of single-cell RNASeq data
Wang, A. L. E.; Lin, Z.; Zanella, L.; Vlahos, L.; Anglada-Girotto, M.; Zafar, A.; Noh, H.; Califano, A.; Vasciaveo, A.
10.1101/2024.08.25.609585 — bioinformatics — Posted on 2024-08-27
838 A long context RNA foundation model for predicting transcriptome architecture
Goodarzi, H.; Najafabadi, H. S.; Ramani, V.; Emad, A.; Namini, A.; Naghipourfar, M.; Wang, S.; Choi, B.; Saberi, A.
10.1101/2024.08.26.609813 — bioinformatics — Posted on 2024-08-27
842 Haplotype-resolved genome assembly of upland switchgrass provides insights into cold tolerance
Wu, B.; Luo, D.; Yue, Y.; Yan, H.; He, M.; Ma, X.; Zhao, B.; Xu, B.; Zhu, J.; Wang, J.; Jia, J.; Sun, M.; Xie, Z.; Wang, X.; Huang, L.
10.1101/2024.08.26.609807 — genomics — Posted on 2024-08-27
843 Epididymis-specific RNase A family genes regulate fertility and small RNA processing
Shaffer, J. F.; Gupta, A.; Kharkwal, G.; Linares, E. E.; Holmes, A. D.; Sharma, U.
10.1101/2024.08.26.608813 — genetics — Posted on 2024-08-27
844 The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNA
Zhu, Y.; Lee, B. J.; Fujii, S.; Jonchhe, S.; Zhang, H.; Li, A.; Wang, K. J.; Rothenberg, E.; Modesti, M.; Zha, S.
10.1101/2024.08.26.609806 — genetics — Posted on 2024-08-27
845 A new tool in a toolbox: Addressing challenges in high-throughput microbiota surveys across diverse wild insects
Buczek, M.; Kolasa, M. R.; Prus-Frankowska, M.; Lipowska, M.; Nowak, K. H.; Azarbad, H.; Franco, D. C.; Marszalek, M.; Roslin, T.; Michalik, A.; Lukasik, P.
10.1101/2024.08.26.609764 — ecology — Posted on 2024-08-27
853 Microbial Weathering Analysis of Anshun Tunbao Artifacts
Abudureyimu, P.; Luo, X.; Gui, C.; Liu, M.; Su, X.; Lan, D.; Chen, Z.; Lon, J. R.; Luo, J.
10.1101/2024.08.26.609815 — microbiology — Posted on 2024-08-27
854 Immunophenotypic changes in peripheral blood of colorectal cancer patients: a potential diagnostic marker for CD4+ monocytes
Thin, K. A.; Cross, A.; Angsuwatcharakon, P.; Mutirangura, A.; Puttipanyalears, C.; Pike, T.; Jones, R.; Skaife, P.; Edwards, S.
10.1101/2024.08.26.609793 — immunology — Posted on 2024-08-27
855 Sodium channel inhibitors alter the progress of tangle development in a mouse model of dementia
Hall, C. M.; Roberts, M.; Desai, R.; Cummings, D. M.; Bisland, J.; Whiting, P.; Smith, K. J.; Edwards, F. A.
10.1101/2024.08.26.609302 — neuroscience — Posted on 2024-08-27
856 Alterations in large-scale resting-state network nodes following transcranial focused ultrasound of deep brain structures
Gorka, S.; Jimmy, J.; Koning, K.; Phan, K. L.; Rotstein, N.; Hoang-Dang, B.; Halavi, S.; Spivak, N.; Monti, M.; Reggente, N.; Bookheimer, S.; Kuhn, T.
10.1101/2024.08.26.609720 — neuroscience — Posted on 2024-08-27
857 Neural correlates of age-related changes in social decisions from episodic memory
van Geen, C.; Cohen, M. S.; Lempert, K. M.; MacNear, K. A.; Reckers, F. M.; Zaneski, L.; Wolk, D. A.; Kable, J. W.
10.1101/2024.08.26.609251 — neuroscience — Posted on 2024-08-27
859 Photoperiodicity in Glucose Metabolism in the Human Brain
Pak, K.; Shin, S.; Kim, K.; Kim, J.; Nam, H. Y.; Nummenmaa, L.; Nuutila, P.; Liu, X.; Sun, L.
10.1101/2024.08.26.609495 — neuroscience — Posted on 2024-08-27
862 Decoding the elite soccer players psychological profile
Bonetti, L.; Vestberg, T.; Jafari, R.; Seghezzi, D.; Ingvar, M.; Kringelbach, M. L.; Filgueiras Goncalves, A.; Petrovic, P.
10.1101/2024.08.25.609552 — neuroscience — Posted on 2024-08-27
865 Maize genetic diversity identifies moisture-dependent root-branch signaling pathways
Scharwies, J. D.; Clarke, T.; Zheng, Z.; Dinneny, A.; Birkeland, S.; Veltman, M. A.; Sturrock, C. J.; Torres-Martinez, H. H.; Viana, W. G.; Khare, R.; Kieber, J.; Pandey, B. K. K.; Bennett, M. J.; Schnable, P. S.; Dinneny, J. R.
10.1101/2024.08.26.609741 — plant biology — Posted on 2024-08-27
866 Kinetic modeling of ethylene biosynthesis and signaling pathways in ripening tomato fruit
Nguyen, T. M. V.; Tran, D. T.; Mata, C. I.; Van de Poel, B.; Nicolai, B.; Hertog, M. L. A. T. M.
10.1101/2024.08.26.607967 — plant biology — Posted on 2024-08-27
868 CXCL12 chemokine dimer signaling modulates acute myelogenous leukemia cell migration through altered receptor internalization
Drouillard, D.; Halyko, M.; Cinquegrani, E.; McAllister, D.; Peterson, F. C.; Marchese, A.; Dwinell, M. B.
10.1101/2024.08.26.609725 — cancer biology — Posted on 2024-08-27
869 Extracellular matrix stiffness determines the phenotypic behavior of dedifferentiated melanoma cells through a DDR1/2-dependent YAP mechanotransduction pathway
Lecacheur, M.; Berestjuk, I.; Carminati, A.; Bouvet, O.; Diazzi, S.; Biber, P.; Rovera, C.; Irondelle, M.; Larbret, F.; Prodhomme, V.; Girard, C. A.; Deckert, M.; Tartare-Deckert, S.
10.1101/2024.08.26.609700 — cancer biology — Posted on 2024-08-27
874 Effects of injury size on local and systemic immune cell dynamics in volumetric muscle loss
Whitaker, R.; Sung, S.; Tylek, T.; Risser, G.; O'Brien, E.; Chua, P. E.; Li, T.; Petrie, R. J.; Binder-Markey, B.; Spiller, K.
10.1101/2024.08.26.609702 — bioengineering — Posted on 2024-08-27
875 Invertebrate species distributions in urban ecosystems are driven by habitat availability, not by anthropogenic drivers
Morpurgo, J.; Remme, R. P.; Mudde, Q. D.; Didaskalou, E. A.; Serwatowska, K. J.; Trimbos, K. B.; Hu, M.; van Bodegom, P. M.
10.1101/2024.08.26.609715 — ecology — Posted on 2024-08-27
877 PCDHGC3 silencing promotes renal carcinoma metastasis via mTOR/HIF2a and lipid metabolism rewiring
Chiara, M.-D.; Celada, L.; Cubiella, T.; Salerno, L.; San-Juan-Guardado, J.; Murias, E.; Da Silva Torres, M.; Suarez-Priede, A.; Weiner, J. A.; Herrada-Manchon, H.; Fernandez, M. A.
10.1101/2024.08.26.609687 — cancer biology — Posted on 2024-08-27
878 Immunogenicity and protection efficacy of self-amplifying and circular mRNA vaccines for SARS-CoV-2
Singh, O. N.; Berry, U.; Joshi, G.; Asuru, T. R.; Chandrasekar, K.; Narayanan, S.; Srivastava, P.; Tiwari, M.; Chattopadhyay, S.; Mehdi, F.; Panda, B. N.; Nayak, D.; Mani, S.; Shrivastava, T.; Batra, G.; Ranjith-Kumar, C.; Guchhait, P.; Surjit, M.
10.1101/2024.08.23.609366 — microbiology — Posted on 2024-08-27
879 Early Hox Gene Expression in Echinoderms
Ezhova, O. V.; Ageenko, N. V.; Kiselev, K. V.; Lukinykh, A. I.; Malakhov, V. V.
10.1101/2024.08.26.609757 — developmental biology — Posted on 2024-08-27
881 Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development
Patel, A.; Freville, A.; Rey, J. A.; Flynn, H. R.; Kousis, K.; Skehel, M. J.; Blackman, M.; Baker, D. A.
10.1101/2024.04.08.588616 — molecular biology — Posted on 2024-08-27
882 Metabolic capabilities are highly conserved among human nasal-associated Corynebacterium species in pangenomic analyses
Tran, T. H.; F. Escapa, I.; Roberts, A. Q.; Gao, W.; Obawemimo, A. C. C.; Segre, J. A.; Kong, H. H.; Conlan, S.; Kelly, M.; Lemon, K. P.
10.1101/2023.06.05.543719 — microbiology — Posted on 2024-08-27
884 Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations.
Kumawat, A.; Tavazzani, E.; Lentini, G.; Trancuccio, A.; Kukavica, D.; Denegri, M.; Priori, S. G.; Camilloni, C.
10.1101/2024.03.13.584147 — biophysics — Posted on 2024-08-27
885 MorphLink: Bridging Cell Morphological Behaviors and Molecular Dynamics in Multi-modal Spatial Omics
Huang, J.; Yuan, C.; Jiang, J.; Chen, J.; Badve, S.; Gokmen-Polar, Y.; Segura, R. L.; Yan, X.; Lazar, A.; Gao, J.; Epstein, M.; Wang, L.; Hu, J.
10.1101/2024.08.24.609528 — bioinformatics — Posted on 2024-08-27
886 Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle
Ghosh, R.; Chandra, G.; Verma, V.; Kaur, K.; Roychoudhury, A.; Mukherjee, S.; Chawla, A.; Mukherjee, K.
10.1101/2024.08.26.609607 — bioengineering — Posted on 2024-08-27
887 Kinome screening identifies integrated stress response kinase EIF2AK1 / HRI as a negative regulator of PINK1 mitophagy signaling
Singh, P.; Agarwal, S.; Volpi, I.; Wilhelm, L. P.; Becchi, G.; Keenlyside, A.; Macartney, T.; Toth, R.; Rousseau, A.; Masson, G.; Ganley, I. G.; Muqit, M. M. K.
10.1101/2023.03.20.533516 — biochemistry — Posted on 2024-08-27
888 Readaptation of mesenchymal stem cells to high stiffness and oxygen environments modulate the extracellular matrix
Caramelo, I.; Domingues, C.; Mendes, V. M.; Anjo, S. I.; Geraldo, M.; Cardoso, C. M. P.; Graos, M.; Manadas, B.
10.1101/2024.08.26.609692 — cell biology — Posted on 2024-08-27
889 Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/beta-catenin signaling
Ntourmas, S.; Sachs, M.; Paclikova, P.; Bruckner, M.; Bryja, V.; Behrens, J.; Bernkopf, D. B.
10.1101/2024.03.07.583872 — cell biology — Posted on 2024-08-27
890 SpinalTRAQ: A novel volumetric cervical spinal cord atlas identifies the corticospinal tract synaptic projectome in healthy and post-stroke mice
Poinsatte, K.; Kenwood, M.; Betz, D.; Nawaby, A.; Ajay, A. D.; Xu, W.; Plautz, E. J.; Kong, X.; Ramirez, D. M. O.; Goldberg, M. P.
10.1101/2024.08.23.609434 — neuroscience — Posted on 2024-08-27
892 BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment
Rios-Jimenez, E.; Zomer, A.; Collot, R.; Barrera Roman, M.; Ariese, H.; L. van Ineveld, R.; Kleinnijenhuis, M.; Bessler, N.; Johnson, H.; Rios, A.; Alieva, M.
10.1101/2024.08.23.609358 — cancer biology — Posted on 2024-08-27
893 Mechanism of expanded DNA recognition in xCas9
Hossain, K. A.; Nierzwicki, L.; Orozco, M.; Czub, J.; Palermo, G.
10.1101/2024.08.26.609653 — biophysics — Posted on 2024-08-27
894 Shared and distinct molecular effects of regulatory genetic variants provide insight into mechanisms of distal enhancer-promoter communication
Ray-Jones, H.; Song, Z.; Chan, L. T.; Haglund, A.; Artemov, P.; Della Rosa, M.; Ruje, L.; Burden, F.; Kreuzhuber, R.; Litovskikh, A.; Weyenbergh, E.; Brusselaers, Z.; Tan, V. X. H.; Frontini, M.; Wallace, C.; Malysheva, V.; Bottolo, L.; Vigorito, E.; Spivakov, M.
10.1101/2023.08.04.551251 — genetics — Posted on 2024-08-27
898 Binding of a pathogen effector to rice Exo70 proteins tethered to the NOI/RIN4 integrated domain of the NLR receptor Pii2 confers immunity against fungi
Fujisaki, K.; Abe, Y.; Sugihara, Y.; Nemoto, K.; Ito, K.; Kanzaki, E.; Ishikawa, K.; Iwai, M.; Utsushi, H.; Saitoh, H.; Takagi, H.; Takeda, T.; Abe, A.; Zheng, S.; Białas, A.; Banfield, M. J.; Kamoun, S.; Terauchi, R.
10.1101/239400 — plant biology — Posted on 2024-08-27
902 NOTCH-driven oscillations control cell fate decisions during intestinal homeostasis
Weterings, S. D. C.; Eto, H.; de Leede, J.-D.; Giladi, A.; Hoekstra, M. E.; Beijk, W.; Liefting, E. J. M.; van den Anker, K. B.; van Rheenen, J.; van Oudenaarden, A.; Sonnen, K. F.
10.1101/2024.08.26.609553 — cell biology — Posted on 2024-08-27
903 Piezo activity levels need to be tightly regulated to maintain normal morphology and function in pericardial nephrocytes
Schulz, K.; Hazelton-Cavill, P.; Alornyo, K. K.; Edenhofer, I.; Lindenmeyer, M.; Lohr, C.; Huber, T. B.; Denholm, B.; Koehler, S.
10.1101/2021.10.23.465463 — cell biology — Posted on 2024-08-27
905 Common DNA sequence variation influences epigenetic aging in African populations
Meeks, G. L.; Scelza, B.; Asnake, H. M.; Prall, S.; Patin, E.; Froment, A.; Fagny, M.; Quintana-Murci, L.; Henn, B. M.; Gopalan, S.
10.1101/2024.08.26.608843 — genetics — Posted on 2024-08-26
907 Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina
Wu, E. G.; Brackbill, N.; Rhoades, C. E.; Kling, A.; Gogliettino, A. R.; Shah, N. P.; Sher, A.; Litke, A. M.; Simoncelli, E. P.; Chichilnisky, E. J.
10.1101/2023.08.12.552902 — neuroscience — Posted on 2024-08-26
909 Impact of intragenic NRXN1 deletions on early cortical development
Dutan-Polit, L.; Gatford, N. J.; Carneiro, T.; Nagy, R.; Higgs, V.; APEX Consortia, ; Massrali, A.; Paul, A.; Fasolino, M.; Zhou, Z.; Flinter, F. A.; Adhya, D.; Bucan, M.; Baron-Cohen, S.; Srivastava, D. P.
10.1101/2024.08.26.609494 — neuroscience — Posted on 2024-08-26
910 A multidisciplinary on-farm survey of maize-bean intercropping highlights key considerations for reviving traditional agricultural systems.
Vazeux-Blumental, N.; Mathieu, L.; Trabac, T.; Palaffre, C.; Lagardere, B.; Carraretto, M.; Bauland, C.; Le Guilloux, M.; Paysant-Le Roux, C.; Caius, J.; Marmagne, A.; Enjalbert, J.; Flutre, T.; Le Cadre, E.; Parnaudeau, V.; Muller, D.; Moenne-Loccoz, Y.; Manicacci, D.; Tenaillon, M. I.
10.1101/2024.04.24.590929 — plant biology — Posted on 2024-08-26
912 Oncogenic Ras activation in permissive somatic cells triggers rapid onset phenotypic plasticity and elicits a tumour-promoting neutrophil response
Elliot, A. M.; Ribeiro Bravo, I.; Astorga Johansson, J.; Hutton, E.; Cunningham, R.; Myllymaki, H.; Chang, K. Y.; Cholewa-Waclaw, J.; Zhao, Y.; Dobie, R.; Beltran, M.; Lewis, A.; Elks, P.; Hansen, C. G.; Henderson, N.; Feng, Y.
10.1101/2023.11.10.566547 — cancer biology — Posted on 2024-08-26
915 Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program
Wang, N.; Ockerman, F. P.; Zhou, L. Y.; Grove, M. L.; Alkis, T.; Barnard, J.; Bowler, R. P.; Clish, C. B.; Chung, S.; Drzymalla, E.; Evans, A. M.; Franceschini, N.; Gerszten, R. E.; Gillman, M. G.; Hutton, S. R.; Kelly, R. S.; Kooperberg, C.; Larson, M. G.; Lasky-Su, J. A.; Meyers, D. A.; Woodruff, P. G.; Reiner, A. P.; Rich, S. S.; Rotter, J.; Silverman, E. K.; Ramachandran, V. S.; Weiss, S. T.; Wong, K. E.; Wood, A. C.; Wu, L.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Yarden, R.; Blackwell, T.; Smith, A. V.; Chen, H.; Raffield, L. M.; Yu, B.
10.1101/2024.07.23.604849 — bioinformatics — Posted on 2024-08-26
919 Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood
Stefanovic, F.; Brown, L.; MacDonald, J.; Bammler, T. K.; Rinchai, D.; Nguyen, S.; Zeng, Y.; Shinkawa, V.; Adams, K.; Chaussabel, D.; Berthier, E.; Haack, A. J.; Theberge, A. B.
10.1101/2024.08.24.609519 — bioengineering — Posted on 2024-08-26
921 Distinct pathogenic influence of anti-HMGCR+ and anti-SRP+ immune-mediated necrotizing myopathy autoantibodies on engineered muscle function
Lad, H.; Esteban, E. M.; Tiper, Y.; Mahoudeau, A.; Xie, Z.; Tendrel, B.; Allenbach, Y.; Benveniste, O.; Gilbert, P. M.
10.1101/2024.08.26.609771 — bioengineering — Posted on 2024-08-26
924 Molecular Mechanism of PP2A/B55α Phosphatase Inhibition by IER5
Cao, R.; Jones, D. T.; Pan, L.; Wang, S.; Padi, S. K. R.; Rawson, S.; Aster, J. C.; Blacklow, S. C.
10.1101/2023.08.29.555174 — biochemistry — Posted on 2024-08-26
926 Allopolyploidy expanded gene content but not pangenomic variation in the hexaploid oilseed Camelina sativa
Bird, K. A.; Brock, J. R.; Grabowski, P. P.; Harder, A. M.; Shu, S.; Barry, K.; Boston, L.; Daum, C.; Guo, J.; Lipzen, A.; Walstead, R.; Grimwood, J.; Schmutz, J.; Lu, C.; Comai, L.; McKay, J. K.; Pires, J. C.; Edger, P. P.; Lovell, J. T.; Kliebenstein, D. J.
10.1101/2024.08.13.607619 — genomics — Posted on 2024-08-26
927 Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer
Safonov, A.; Marra, A.; Bandlamudi, C.; O'Leary, B.; Wubbenhorst, B.; Ferraro, E.; Moiso, E.; Lee, M.; An, J. A.-R.; Donoghue, M.; Will, M.; Pareja, F.; Nizialek, E.; Lukashchuk, N.; Sofianopoulou, E.; Liu, Y.; Huang, X.; Ahmed, M.; Mehine, M. M.; Ross, D.; Mandelker, D.; Schultz, N.; Berger, M.; Scaltriti, M.; Reis-Filho, J. S.; Li, B. T.; Offit, K.; Norton, L.; Shen, R.; Shah, S.; Maxwell, K. N.; Couch, F.; Domchek, S. M.; Solit, D. B.; Nathanson, K. L.; Robson, M. E.; Turner, N. C.; Chandarlapaty, S.; Razavi, P.
10.1101/2024.02.05.578934 — genomics — Posted on 2024-08-26
928 A Draft Pacific Ancestry Pangenome Reference
Littlefield, C. C.; Lazaro-Guevara, J. M.; Stucki, D.; Lansford, M.; Pezzolesi, M. H.; Taylor, E. J.; Wolfgramm, E. M. C.; Taloa, J.; Lao, K.; Dumaguit, C. D. C.; Ridge, P. G.; Tavana, J. P.; Holland, W. L.; Raphael, K. L.; Pezzolesi, M. G.
10.1101/2024.08.07.606392 — genomics — Posted on 2024-08-26
929 Electrostatic changes enabled the diversification of an exocyst subunit via protein complex escape
De la Concepcion, J. C.; Duverge, H.; Kim, Y.; Julian, J.; Xu, D.; Ikene, S. A.; Bianchi, A.; Grujic, N.; Papareddy, R.; Grishkovskaya, I.; Haselbach, D.; Murray, D.; Clavel, M.; Irwin, N.; Dagdas, Y.
10.1101/2024.08.26.609756 — evolutionary biology — Posted on 2024-08-26
930 Proteome asymmetry in mouse and human embryos before fate specification
Iwamoto-Stohl, L. K.; Petelski, A. A.; Meglicki, M.; Fu, A.; Khan, S.; Specht, H.; Huffman, G.; Derks, J.; Jorgensen, V.; Weatherbee, B. A.; Weberling, A.; Gantner, C. W.; Mandelbaum, R. S.; Paulson, R. J.; Lam, L.; Ahmady, A.; Vasquez, E. S.; Slavov, N.; Zernicka-Goetz, M.
10.1101/2024.08.26.609777 — developmental biology — Posted on 2024-08-26
932 The sperm hook in house mice: a functional adaptation for migration and self-organised behaviour
Ryu, H.; Nam, K.; Lee, B. E.; Jeong, Y.; Lee, S.; Kim, J.; Hyun, Y.-M.; Kim, J.-I.; Park, J.-H.
10.1101/2024.02.19.581047 — cell biology — Posted on 2024-08-26
934 Subcellular context-specific tuning of actomyosin ring contractility within a common cytoplasm
Linehan, J.; Zampetaki, A.; Werner, M.; Heck, B.; Maddox, P.; Furthauer, S.; Maddox, A. S.
10.1101/2024.08.08.607200 — cell biology — Posted on 2024-08-26
935 Novel RNA-binding protein YebC enhances translation of proline-rich amino acid stretches in bacteria
Ignatov, D.; Shanmuganathan, V.; Ahmed-Begrich, R.; Alagesan, K.; Frese, C. K.; Wang, C.; Krause, K.; Charpentier, E.
10.1101/2024.08.26.607280 — molecular biology — Posted on 2024-08-26
938 The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites
Lo, J.; Vaeth, K. F.; Bhardwaj, G.; Mukherjee, N.; Russ, H. A.; Moore, J.; Taliaferro, M.
10.1101/2024.08.26.609768 — molecular biology — Posted on 2024-08-26
939 De novo design of potent inhibitors of Clostridioides difficile toxin B
Ragotte, R. J.; Tam, J.; Miletic, S.; Palou, R.; Weidle, C.; Li, Z.; Gloegl, M.; Beilhartz, G. L.; Liang, H.; Carr, K. D.; Borst, A. J.; Coventry, B.; Wang, X.; Rubinstein, J. L.; Tyers, M.; Melnyk, R. A.; Baker, D.
10.1101/2024.08.26.609740 — microbiology — Posted on 2024-08-26
940 ANALYSIS OF RESPIRATORY SYNCYTIAL VIRUS REVEALS CONSERVED RNA SECONDARY STRUCTURAL MOTIFS AND IMPACT VIRAL LIFECYCLE
Thornhill, E. M.; Andrews, R. J.; Lozier, Z.; Carino, E.; Rameix-Welti, M.-A.; Eleouet, J.-F.; Moss, W.; Verhoeven, D.
10.1101/2024.08.26.609688 — microbiology — Posted on 2024-08-26
942 NSC95397 is a Novel HIV-1 Latency Reversing Agent
Nichols Doyle, R.; Yang, V.; Kayode, Y. I.; Damoiseaux, R.; Taylor, H. E.; Fregoso, O. I.
10.1101/2023.05.24.542213 — microbiology — Posted on 2024-08-26
943 AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid
Chen, D. F.; Roe, L. T.; Li, Y.; Borges, A. L.; Zhang, J. Y.; Babbar, P.; Maji, S.; Stevens, M. G. V.; Correy, G. J.; Diolaiti, M. E.; Smith, D. H.; Ashworth, A.; Stroud, R. M.; Kelly, M. J. S.; Bondy-Denomy, J.; Fraser, J. S.
10.1101/2024.08.26.609590 — microbiology — Posted on 2024-08-26
944 Persistent legacy effects on soil metagenomes facilitate plant adaptive responses to drought
Ginnan, N. A.; Custodio, V.; Gopaulchan, D.; Ford, N.; Salas-Gonzalez, I.; Jones, D. D.; Wells, D. M.; Moreno, A.; Castrillo, G.; Wagner, M. R.
10.1101/2024.08.26.609769 — microbiology — Posted on 2024-08-26
948 Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons
LeBlang, C. J.; Pazyra-Murphy, M. F.; Silagi, E. S.; Dasgupta, S.; Tsolias, M.; Miller, T.; Petrova, V.; Zhen, S.; Jovanovic, V.; Castellano, D.; Gerrish, K.; Ormanoglu, P.; Tristan, C.; Singec, I.; Woolf, C. J.; Tasdemir-Yilmaz, O.; Segal, R. A.
10.1101/2024.07.24.604966 — neuroscience — Posted on 2024-08-26
949 A myelinic channel system for motor-driven organelle transport
Edgar, J. M.; Chapple, K. J.; Wirth, S.; Chen, Y.-H.; Gerwig, U.; Aicher, M. L.; Kim, Y.; Green, T.; Komarek, L.; Brown, A. M.; Pardo-Fernandez, L.; Crawford, C. L.; Smith, R. S.; Lee, J.; Werner, H. B.; Kassmann, C.; Davis, I.; Kneussel, M.; Brown, E. R.; Goebbels, S.; Nave, K.-A.
10.1101/2024.06.02.591488 — neuroscience — Posted on 2024-08-26
950 FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling
Khan, M. S. H.; Kim, S. Q.; Ross, R. C.; Corpodean, F.; Spann, R. A.; Albarado, D. A.; Fernandez-Kim, S. O.; Clarke, B.; Berthoud, H.-R.; Münzberg, H.; McDougal, D. H.; He, Y.; Yu, S.; Albaugh, V. L.; Soto, P.; Morrison, C. D.
10.1101/2024.03.05.583399 — neuroscience — Posted on 2024-08-26
952 Motor neurons are dispensable for the assembly of a sensorimotor circuit for gaze stabilization
Goldblatt, D.; Rosti, B.; Hamling, K. R.; Leary, P.; Panchal, H.; Li, M.; Huang, S.; Quainoo, C.; Schoppik, D.
10.1101/2024.01.25.577261 — neuroscience — Posted on 2024-08-26
953 Focal control of non-invasive deep brain stimulation using multipolar temporal interference
Botzanowski, B.; ACERBO, E.; lehmann, s.; Kearsley, S. L.; Steiner, M.; Neufeld, E.; MISSEY, F.; Muller, L.; Jirsa, V.; Corneil, B. D.; Williamson, A.
10.1101/2023.09.05.556444 — neuroscience — Posted on 2024-08-26
955 A novel iPSC model of Bryant-Li-Bhoj neurodevelopmental syndrome demonstrates the role of histone H3.3 in neuronal differentiation and maturation
Sangree, A. K.; Angireddy, R.; Bryant, L. M.; Layo-Carris, D. E.; Lubin, E. E.; Wang, X. M.; Clark, K. J.; Durham, E. E.; Bhoj, E. J.
10.1101/2024.08.26.609745 — neuroscience — Posted on 2024-08-26
957 Chickpea NCR13 disulfide cross-linking variants exhibit profound differences in antifungal activity and modes of action
Godwin, J.; Djami-Tchatchou, A. T.; Velivelli, S. L. S.; Tetorya, M.; Kalunke, R.; Pokhrel, A.; Zhou, M.; Buchko, G. W.; Czymmek, K.; Shah, D.
10.1101/2024.08.09.607347 — plant biology — Posted on 2024-08-26
958 Phospho-proteomics identifies D-group MAP kinases as substrates of the Arabidopsis tyrosine phosphatase RLPH2
Labandera, A.-M.; Toth, R.; Mitchell, S.; Johnson, J.; Puyaubert, J.; Baudouin, E.; Uhrig, R. G.; Moorhead, G.
10.1101/2024.08.26.609716 — plant biology — Posted on 2024-08-26
959 Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55α
Sergienko, N. M.; Trewin, A. J.; Kiriazis, H.; Raaijmakers, A. J.; Donner, D. G.; Garside, V. C.; Smith, K. A.; Bell, J. R.; Mellor, K. M.; Delbridge, L. M.; McMullen, J. R.; Weeks, K. L.
10.1101/2024.05.05.592558 — physiology — Posted on 2024-08-26
960 Water and chloride as allosteric inhibitors in WNK kinase osmosensing
Goldsmith, E. J.; Teixeira, L. R.; Radha, A.; Humphreys, J. M.; He, H.
10.1101/2023.08.29.555411 — biophysics — Posted on 2024-08-26
961 Bats from the Colombian Caribbean Reveal a new subtype of Influenza A (H18N12)
Echeverri-De la Hoz, D.; Martinez-Bravo, C.; Gastelbondo-Pastrana, B.; Rivero, R.; Lopez, Y.; Hoyos, R.; Aleman, M.; Garay, E.; Bertel, V.; Arrieta, G.; Ramirez, J. D.; Mattar, S.
10.1101/2024.08.25.609627 — bioinformatics — Posted on 2024-08-26
962 Photo-induced changes in tissue stiffness alter epithelial budding morphogenesis in the embryonic lung
Peak, K. E.; Rajaguru, P.; Khan, A.; Gleghorn, J. P.; Obaid, G.; Ferruzzi, J.; Varner, V. D.
10.1101/2024.08.22.609268 — bioengineering — Posted on 2024-08-26
969 Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion
Ma, F.; Chen, S.; Calagua, C.; Arai, S.; Xie, F.; Voznesensky, O.; Poluben, L.; Corey, E.; Cai, C.; Wang, Y.; Einstein, D.; Taplin, M.-E.; Ye, H.; Sowalsky, A. G.; Russo, J.; Yuan, X.; Balk, S.
10.1101/2024.08.26.609679 — cancer biology — Posted on 2024-08-26
970 Extensive exploration of structure activity relationships for the SARS-CoV-2 macrodomain from shape-based fragment merging and active learning
Correy, G. J.; Rachman, M. M.; Togo, T.; Gahbauer, S.; Doruk, Y. U.; Stevens, M. G. V.; Jaishankar, P.; Kelley, B.; Goldman, B.; Schmidt, M.; Kramer, T.; Ashworth, A.; Riley, P.; Shoichet, B. K.; Renslo, A. R.; Walters, W. P.; Fraser, J. S.
10.1101/2024.08.25.609621 — biophysics — Posted on 2024-08-26
971 Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle
Ghosh, R.; Chandra, G.; Verma, V.; Kaur, K.; Roychoudhury, A.; Mukherjee, S.; Chawla, A.; Mukherjee, K.
10.1101/2024.08.26.609607 — bioengineering — Posted on 2024-08-26
972 Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus
Tortorici, M. A.; Choi, A.; Gibson, C.; Lee, J.; Brown, J. T.; Stewart, C.; Joshi, A.; Harari, S.; Willoughby, I.; Treichel, C.; Leif, E.; Bloom, J. D.; King, N. P.; Tait-Burkard, C.; Whittaker, G. R.; Veesler, D.
10.1101/2024.08.25.607996 — biochemistry — Posted on 2024-08-26
974 Using Dual-Coil TMS-EEG to Probe Bilateral Brain Mechanisms in Healthy Aging and Mild Cognitive Impairment
Morales-Torres, R.; Hovhannisyan, M.; Gamboa, O. L.; Dannhauer, M.; McAllister, M. L.; Roberts, K.; Li, Y.; Peterchev, A. V.; Woldorff, M. G.; Davis, S. W.
10.1101/2024.08.23.609391 — neuroscience — Posted on 2024-08-26
975 Natural Language Processing Applied to Spontaneous Recall of Famous Faces Reveals Memory Dysfunction in Temporal Lobe Epilepsy Patients
Tefera, E.; Borges Delfino de Souza, H.; Blewitt, C.; Mansoor, A.; Peters, H.; Teerawanichpol, P.; Henin, S.; Barr, W.; Johnson, S. B.; Liu, A.
10.1101/2024.08.23.609193 — neuroscience — Posted on 2024-08-26
977 Highjacked by a pseudoenzyme: How eudicot plants make indole
Florean, M.; Schultz, H.; Grabe, V.; Luck, K.; O'Connor, S. E.; Kollner, T. G.
10.1101/2024.08.26.609694 — plant biology — Posted on 2024-08-26
979 Comparative analysis of trans-chromosomic rodent models reveals improved somatic hypermutation and class-switch recombination in rats
Satofuka, H.; Abe, S.; Moriwaki, T.; Okada, A.; Kazuki, K.; Hamamichi, S.; Hiratsuka, M.; Hirabayashi, M.; Nakamura, K.; Sakuma, T.; Yamamoto, T.; Baba, Y.; Tomizuka, K.; Kazuki, Y.
10.1101/2024.08.26.609625 — bioengineering — Posted on 2024-08-26
982 LAT encodes T cell activation pathway balance
Rubin, A. J.; Dao, T. T.; Schueppert, A. V.; Regev, A.; Shalek, A. K.
10.1101/2024.08.26.609683 — genomics — Posted on 2024-08-26
983 Near-infrared spectroscopy discriminates mass-reared sterile and wild tsetse flies
Pagabeleguem, S.; Da, D. F.; Some, B. M.; Avelessi, M. S. P.; Djegbe, N. D. C.; Yoda, R. L.; Bagayogo, A.; MAIGA, H. M.; Churcher, T.; Dabire, R. K.
10.1101/2024.08.26.609677 — evolutionary biology — Posted on 2024-08-26
985 Actin Polymerization Status Regulates Tendon Homeostasis through Myocardin-Related Transcription Factor-A
West, V.; Owen, K.; Inguito, K. L.; Ebron, K. M. M.; Reiner, T.; Mirack, C. E.; Le, C.; Marqueti, R. d. C.; Snipes, S.; Mousavizadeh, R.; Elliott, D.; Parreno, J.
10.1101/2024.08.26.609684 — cell biology — Posted on 2024-08-26
986 Readaptation of mesenchymal stem cells to high stiffness and oxygen environments modulate the extracellular matrix
Caramelo, I.; Domingues, C.; Mendes, V. M.; Anjo, S. I.; Geraldo, M.; Cardoso, C. M. P.; Graos, M.; Manadas, B.
10.1101/2024.08.26.609692 — cell biology — Posted on 2024-08-26
990 Synthetic enhancers reveal design principles of cell state specific regulatory elements in hematopoiesis
Fromel, R.; Ruhle, J.; Bernal Martinez, A.; Szu-Tu, C.; Pacheco Pastor, F.; Martinez Corral, R.; Velten, L.
10.1101/2024.08.26.609645 — molecular biology — Posted on 2024-08-26
992 Metagenomic insights into an enigmatic gammaproteobacterium that is important for carbon cycling in cave ecosystems worldwide
Jones, D. S.; Green, K. M.; Brown, A.; Havlena, Z. E.; Best, M. B.; Northup, D. E.; Mainiero, M.; Auch, B.
10.1101/2024.08.23.608578 — microbiology — Posted on 2024-08-26
994 Mtb specific HLA-E restricted T cells are induced during Mtb infection but not after BCG administration in non-human primates and humans
Voogd, L.; van Wolfswinkel, M.; Satti, I.; White, A. D.; Dijkman, K.; Gela, A.; van Meijgaarden, K. E.; Franken, K. L. M. C.; Marshall, J. L.; Ottenhoff, T. H. M.; Scriba, T.; McShane, H.; Sharpe, S. A.; Verreck, F. A. W.; Joosten, S. A.
10.1101/2024.08.26.609630 — immunology — Posted on 2024-08-26
996 Investigating microscopic angioarchitecture in the human visual cortex in 3D with angioMASH tissue clearing and labelling
Hildebrand, S.; Franz, J.; Hoogen, H.; Capalbo, M.; Bethge, P.; Herrler, A.; Helmchen, F.; Roebroeck, A.
10.1101/2024.08.26.609648 — neuroscience — Posted on 2024-08-26
997 Progressive changes in functional connectivity between thalamic nuclei and cortical networks across learning
Jarrett, C. E.; Zwosta, K.; Wang, X.; Wolfensteller, U.; Iglesias, J. E.; von Kriegstein, K.; Ruge, H.
10.1101/2024.08.26.609333 — neuroscience — Posted on 2024-08-26
1002 Chloroplastic ROS bursts initiate salicylic acid biosynthesis in plant immunity
Roussin-Leveillee, C.; St-Amand, M.; Desbiens-Fortin, P.; Perreault, R.; Pelletier, A.; Gauthier, S.; Gaudreault-Lafleur, F.; Laforest-Lapointe, I.; Moffett, P.
10.1101/2024.08.26.609370 — plant biology — Posted on 2024-08-26
1003 SIRT5-mediated GLS and GDH desuccinylation attenuates autophagy in MAC-T cells induced by ammonia
Wang, Y.; Yang, H.; Gao, S.; Lu, G.; He, J.; Dong, J.; Zhang, X.; Liu, L.; Zhong, K.; Zha, G.; Han, L.; Guo, S.; Li, H.
10.1101/2024.08.26.609685 — physiology — Posted on 2024-08-26
1006 Pipeline for Assessing Tumor Immune Status Using Superplex Immunostaining and Spatial Immune Interaction Analysis
Xiao, C.; Zhou, R.; Chen, Q.; Hou, W.; Li, X.; Wang, Y.; Liu, L.; Wang, H.; Yao, X.; Xu, T.; Cao, F.; Yin, B.; Yan, O.; Jiang, L.; Wang, W.; Cao, D.; Zhao, C.
10.1101/2024.08.23.609368 — cancer biology — Posted on 2024-08-26
1012 Dissecting heterogeneity of tumor microenvironment in colorectal cancer using high-resolution single-cell atlas
Marteau, V.; Nemati, N.; Handler, K.; Raju, D.; Soto, E. K.; Fotakis, G.; Carollo, S.; Boeck, N.; Kirchmair, A.; Scheiber, A.; Ammann, A.; Seeber, A.; Gasser, E.; Horvath, L.; Fazilaty, H.; Valenta, T.; Sturm, G.; Rieder, D.; Sopper, S.; Pircher, A.; Ziegler, P.; Tschurtschenthaler, M.; Wolf, D.; Arnold, I.; Salcher, S.; Trajanoski, Z.
10.1101/2024.08.26.609563 — bioinformatics — Posted on 2024-08-26
1013 Data-guided direct reprogramming of human fibroblasts into the hematopoietic lineage
Stansbury, C.; Cwycyshyn, J.; Pickard, J.; Meixner, W.; Rajapakse, I.; Muir, L. A.
10.1101/2024.08.26.609589 — bioinformatics — Posted on 2024-08-26
1014 funkea: Functional Enrichment Analysis in Python
Tenmann, B.; Close, K.; Rodriguez-Martinez, A.; Abujudeh, S.
10.1101/2024.08.24.609502 — bioinformatics — Posted on 2024-08-26
1015 Cluster Buster: A Machine Learning Algorithm for Genotyping SNPs from Raw Data
Martin, J. L.; Kuznetsov, N.; Levine, K.; Koretsky, M.; Hong, S.; Vitale, D.; Nalls, M. A.
10.1101/2024.08.23.609429 — bioinformatics — Posted on 2024-08-26
1016 Vasculature segmentation in 3D hierarchical phase-contrast tomography images of human kidneys
Jain, Y.; Walsh, C. L.; Yagis, E.; Aslani, S.; Nandanwar, S.; Zhou, Y.; Ha, J.; Gustilo, K. S.; Brunet, J.; Rahmani, S.; Tafforeau, P.; Bellier, A.; Weber, G. M.; Lee, P. D.; Borner, K.
10.1101/2024.08.25.609595 — bioinformatics — Posted on 2024-08-26
1019 Proteolysis targeting chimera extracellular vesicles for therapeutic development treating triple negative breast cancer
Erwin, N.; De, U.; Xiao, Y.; Wang, L.; Maharjan, C.; Pan, X.; Awasthee, N.; Zheng, G.; Liao, D.; Zhang, W.; He, M.
10.1101/2024.08.25.609564 — bioengineering — Posted on 2024-08-26
1024 Habitat partitioning and spatial segregation at multiple scales promotes year-round coexistence in a guild of forest songbirds
Berlusconi, A.; Castiglione, G.; Wauters, L. A.; Martinoli, A.; Clerici, E.; Mologni, A.; Morganti, M.; Martinoli, A.; Romano, A.; Rubolini, D.
10.1101/2024.08.26.609673 — animal behavior and cognition — Posted on 2024-08-26
1028 Declining juvenile survival of Adelie penguins in Antarctica
Barracho, T.; Bardon, G.; Choquet, R.; Houstin, A.; Winterl, A.; Beaulieu, M.; Blanchard, P.; Cornet, C. C.; Cristofari, R.; Raclot, T.; Richter, S.; Chatelain, N.; Courtecuisse, J.; Brucker, M.; Zitterbart, D. P.; Lecomte, N.; Le Bohec, C.
10.1101/2024.08.23.609289 — ecology — Posted on 2024-08-26
1034 MED26-enriched condensates drive erythropoiesis through modulating transcription pausing
Zhu, S.; Zhang, X.; Li, N.; Zhao, X.; Li, M.; Xie, S.; Yue, Q.; Li, Y.; Li, D.; Wu, F.; Zhang, Z.; Feng, Z.; Zhang, Y.; Choi, W.; Jia, X.; Deng, Y.; Hu, Q.; Yao, X.; Gao, X.; Lee, H.-Y. S.
10.1101/2024.08.26.609654 — cell biology — Posted on 2024-08-26
1036 Cell wall arabinogalactan is responsible for Fungitell(R) cross reactivity in nocardiosis
Mariller, C.; Letowski, P.; Chang, W.-T.; Lowary, T.; Ulrich, M.; Faure, K.; Loridant, S.; Sendid, B.; Wallet, F.; Poulain, D.; Hazzan, M.; Frimat, M.; Guerardel, Y.; Titecat, M.
10.1101/2024.08.22.608962 — microbiology — Posted on 2024-08-26
1043 Industrializing yeast as a drug repurposing platform for inherited metabolic diseases
Thevandavakkam, M. A.; Long, N. E.; Roel, B. M.; Kantautas, K. A.; Zakin, S.; Duesterberg, V.; Perlstein, E. O.
10.1101/2024.08.23.609415 — systems biology — Posted on 2024-08-26
1048 Widespread Neuroanatomical Integration and Distinct Electrophysiological Properties of Glioma-Innervating Neurons
Hsieh, A. L.; Ganesh, S.; Kula, T.; Irshad, M.; Ferenczi, E. A.; Wang, W.; Chen, Y.-C.; Hu, S.-H.; Li, Z.; Joshi, S.; Haigis, M. C.; Sabatini, B. L.
10.1101/2024.08.25.609573 — cancer biology — Posted on 2024-08-26
1052 NOTCH-driven oscillations control cell fate decisions during intestinal homeostasis
Weterings, S. D. C.; Eto, H.; de Leede, J.-D.; Giladi, A.; Hoekstra, M. E.; Beijk, W.; Liefting, E. J. M.; van den Anker, K. B.; van Rheenen, J.; van Oudenaarden, A.; Sonnen, K. F.
10.1101/2024.08.26.609553 — cell biology — Posted on 2024-08-26
1053 N-Acetylglucosamine Facilitates Coordinated Myoblast Flow, Forming the Foundation for Efficient Myogenesis
Satoh, M. S.; Rancort, A.; St-Pierre, G.; Bouchard, E.; Fillion, M.; Hagiwara, K.; Nakajima, K.; Sato, S.
10.1101/2024.08.25.609576 — cell biology — Posted on 2024-08-26
1054 A Tale of Two Environments: Divisive Normalization and the (In)Flexibility of Choice
Kurtz David, V.; Sinha, S.; Alladi, V.; Bucher, S.; Brandenburger, A.; Louie, K.; Glimcher, P.; Tymula, A.
10.1101/2024.08.25.609561 — neuroscience — Posted on 2024-08-26
1055 Repetitive neonatal pain increases spinal cord DNA methylation of the μ-opioid receptor
Baudat, M.; Joosten, E. A. J.; Simons, S. H. P.; van den Hove, D. L. A.; Riemens, R. J. M.
10.1101/2024.08.25.609598 — neuroscience — Posted on 2024-08-26
1056 Meisoindigo: An Effective Inhibitor of SARS-CoV-2 Main Protease Revealed by Yeast System
Grabinski, W.; Kicinska, A.; Kosicka, E.; Baranek-Grabinska, M.; Hejenkowska, E. D.; Budzik, J.; Sliska, P.; Sliwinska, W.; Karachitos, A.
10.1101/2023.09.03.555867 — pharmacology and toxicology — Posted on 2024-08-26
1060 Evolution of the Spatial transcriptomic landscape during the progression of high-grade pancreatic intraductal papillary mucinous neoplasms to invasive cancer
Peng, S.; Chen, Q.; Chen, Z.; Yao, M.; Cai, Y.; He, D.; Cai, Y.; Cheng, K.; Li, J.; Cai, H.; Gao, P.; Gu, X.; Wang, X.; Li, Y.; Zhang, M.; Meng, L.; Xia, Q.; Xu, P.; Zhou, J.; Wu, Z.; Peng, B.
10.1101/2024.08.24.608470 — cancer biology — Posted on 2024-08-26
1061 E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model.
Sayed, I. M.; Chakraborty, A.; Inouye, K.; Dugan, L.; Tocci, S.; Advani, I.; Park, K.; Hazra, T. K.; Das, S.; Crotty Alexander, L. E.
10.1101/2024.08.23.609469 — cancer biology — Posted on 2024-08-26
1064 Developing and characterising decellularized extracellular matrix hydrogels to bio-fabricate female reproductive tissues
Ribes Martinez, E.; Franko, Y.; Franko, R.; Ferronato, G.; Viana, A.; Windenbach, E.; Stoeckl, J.; Frolich, T.; de Almeida Monteiro Melo Ferraz, M.
10.1101/2024.08.24.609513 — bioengineering — Posted on 2024-08-26
1071 Segment AnyNeuron
Razzaq, T.; Qazi, A.; Iqbal, A.
10.1101/2024.08.24.609505 — neuroscience — Posted on 2024-08-26
1072 Structural and functional dissection of the Pacinian corpuscle reveals an active role of the inner core in touch detection
Ziolkowski, L. H.; Nikolaev, Y. A.; Chikamoto, A.; Oda, M.; Feketa, V. V.; Monedero-Alonso, D.; Ardasheva, S. A.; Bae, S. S.; Xu, C. S.; Pang, S.; Gracheva, E. O.; Bagriantsev, S. N.
10.1101/2024.08.24.609509 — neuroscience — Posted on 2024-08-26
1074 Glymphatic clearance is enhanced during sleep
Kroesbergen, E.; Riesselmann, L. V.; Gomolka, R. S.; Pla, V.; Esmail, T.; Stenmo, V. H.; Kovacs, E. R.; Nielsen, E. S.; Goldman, S. A.; Nedergaard, M.; Weikop, P.; Mori, Y.
10.1101/2024.08.24.609514 — neuroscience — Posted on 2024-08-26
1075 SynPull: a novel method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
Kedia, S.; Fertan, E.; Wu, Y.; Zhang, Y. P.; Meisl, G.; Lam, J. Y. L.; Wiseman, F. K.; McEwan, W. A.; Quaegebeur, A.; Spillantini, M. G.; Danial, J.; Klenerman, D.
10.1101/2024.08.24.609517 — neuroscience — Posted on 2024-08-26
1077 BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma
Clark, C.; Barzegar Behrooz, A.; Da Silva Rosa, S. C.; Jacobs, J.; Weng, X.; Srivastava, A.; Vitorino, R.; Ande, S. R.; Ravandi, A.; Dhingra, S.; Pecic, S.; Miller, D.; Shojaei, S.; Ghavami, S.
10.1101/2024.08.23.609447 — cancer biology — Posted on 2024-08-26
1078 A forward genetic screen identifies Sirtuin1 as a driver of neuroendocrine prostate cancer
Nunes de Almeida, F.; Vasciaveo, A.; Antao, A. M.; Zou, M.; Di Bernardo, M.; de Brot, S.; Rodriguez-Calero, A.; Chui, A.; Wang, A. L. E.; Floch, N.; Kim, J. Y.; Afari, S. N.; Mukhammadov, T.; Arriaga, J. M.; Lu, J.; Shen, M. M.; Rubin, M.; Califano, A.; Abate-Shen, C.
10.1101/2024.08.24.609538 — cancer biology — Posted on 2024-08-26
1080 msiFlow: Automated Workflows for Reproducible and Scalable Multimodal Mass Spectrometry Imaging and Immunofluorescence Microscopy Data Processing and Analysis
Spangenberg, P.; Bessler, S.; Widera, L.; Bottek, J.; Richter, M.; Thiebes, S.; Siemes, D.; Krauss, S.; Migas, L. G.; Kasarla, S. S.; Phapale, P.; Kleesiek, J.; Fuehrer, D.; Moeller, L. C.; Heuer, H.; Van de Plas, R.; Gunzer, M.; Soehnlein, O.; Soltwisch, J.; Shevchuk, O.; Dreisewerd, K.; Engel, D. R.
10.1101/2024.08.24.609403 — bioinformatics — Posted on 2024-08-26
1081 tombRaider - improved species and haplotype recovery from metabarcoding data through artefact and pseudogene exclusion.
Jeunen, G.-J.; Fernandes, K.; Dowle, E.; Kroos, G. C.; Mauvisseau, Q.; Torma, M.; Miller, A. K.; Lamare, M.; Gemmell, N.
10.1101/2024.08.23.609468 — bioinformatics — Posted on 2024-08-26
1087 A genetically encoded fluorescent reporter for polyamines
Sharma, P.; Kim, C. Y.; Keys, H. R.; Imada, S.; Joseph, A. B.; Ferro, L.; Kunchok, T.; Anderson, R.; Yilmaz, O. H.; Weng, J.-K.; Jain, A.
10.1101/2024.08.24.609500 — cell biology — Posted on 2024-08-26
1088 Dynamic alterations of dural and bone marrow B cells in an animal model of progressive multiple sclerosis
Florescu, A.; Zuo, M.; Wang, A. A.; Champagne-Jorgensen, K.; Noor, M. A.; Ward, L. A.; van Puijenbroek, E.; Klein, C.; Gommerman, J.
10.1101/2024.08.23.609437 — immunology — Posted on 2024-08-26
1089 Assembly and performance of a cholera RDT prototype that detects both Vibrio cholerae and associated bacteriophage as a proxy for pathogen detection
SAYEED, M. A.; Nabil, I. K.; Bhattacharjee, P.; Hossain, M. S.; Akter, N. J.; Akter, R.; Kelley, K. L.; Karim, M.; Begum, Y. A.; Bhuiyan, T. R.; Qadri, F.; Khan, A. I.; Nelson, E. J.
10.1101/2024.08.23.609438 — immunology — Posted on 2024-08-26
1090 Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception
Chen, Y.-T.; de Thomas Wagner, D.; Loutit, A. J.; Nourizonoz, A.; Croisier-Coeytaux, M.-C.; Blanc, J.; Knott, G.; Lee, K.-S.; Huber, D.
10.1101/2024.08.23.609459 — neuroscience — Posted on 2024-08-26
1091 Neurons as biosensors for discriminating neurological disorders in a brain-on-chip platform: Application to Alzheimer s Disease using patient CSF
Miny, L.; Rontard, J.; Allouche, A.; Violle, N.; Dubuisson, L.; Batut, A.; Ponomarenko, A.; Talbi, R.; Gautier, H.; Maisonneuve, B.; Roux, S.; Larramendy, F.; Honegger, T.; Quadrio, I.
10.1101/2024.08.23.609425 — neuroscience — Posted on 2024-08-26
1093 Amyloid-β deposition in basal frontotemporal cortex is associated with selective disruption of temporal mnemonic discrimination
Vanderlip, C.; Taylor, L.; Kim, S.; Harris, A. L.; Tuteja, N.; Meza, N.; Escalante, Y. Y.; McMillan, L.; Yassa, M. A.; Adams, J. N.
10.1101/2024.08.23.609449 — neuroscience — Posted on 2024-08-26
1094 Ischemic lesions to inferior frontal cortex alter the dynamics of conscious visual perception
Fritsch, M.; Michely, J.; Jaeckel, L.; Rangus, I.; Riegler, C.; Scheitz, J.; Nolte, C. H.; Sterzer, P.; Weilnhammer, V.
10.1101/2024.08.24.609496 — neuroscience — Posted on 2024-08-26
1096 Optimization of Seizure Prevention by Cannabidiol (CBD)
Bhandari, B.; Emami Naeini, S.; Rezaei, S.; Rogers, H. M.; Khodadadi, H.; Bosomtwi, A.; Seyyedi, M.; MacKinnon, N. J.; Dhandapani, K. M.; Lopes Salles, E.; Hess, D. C.; Yu, J. C.; Moore-Hill, D.; Vale, F. L.; Wang, L. P.; Baban, B.
10.1101/2024.08.24.609518 — neuroscience — Posted on 2024-08-26
1098 Longitudinally cultured precision cut lung slices as a predictive ex vivo model for lung cancer
Sargsian, A.; Girmatsion, H.; Lenders, V.; Ghesquiere, B.; Takeno Cologna, C.; Soenen, S. J.; Manshian, B. B.
10.1101/2024.08.23.609442 — cancer biology — Posted on 2024-08-26
1099 TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION
Restaino, A. C.; Ahmadi, M.; Nikpoor, A. R.; Walz, A.; Balood, M.; Eichwald, T.; Talbot, S.; Vermeer, P. D.
10.1101/2024.08.23.609450 — cancer biology — Posted on 2024-08-26
1100 Statins attenuate Wnt/β-catenin signaling by targeting SATB family proteins in colorectal cancer
Tripathi, S.; Gupta, E.; Naik, R.; Khare, S.; Mir, R.; Yadav, S.; Desai, S.; Humane, S.; Bal, M.; Saklani, A.; Patil, P.; Kamat, S.; Galande, S.
10.1101/2024.08.23.609189 — cancer biology — Posted on 2024-08-26
1101 Spatio-temporal segmentation of contraction waves in the extra-embryonic membranes of the red flour beetle
Pereyra, M.; Golden, M.; Lange, Z.; Golden, A.; Strobl, F.; Stelzer, E. H. K.; Matthaeus, F.
10.1101/2024.08.23.609389 — bioinformatics — Posted on 2024-08-26
1103 Functional high capacity exosome-encapsulating bioinspired hydrogel promotes microvascularbed expansion in diabetic mice
Subhan, B. S.; Cortes Troncoso, J. F.; Katyal, P.; Meleties, M.; Mestvirishvili, T.; Arias, F.; Wang, A.; Ruggles, K.; Dolgalev, I.; Mita, P.; Montclare, J. K.; Rabbani, P. S.
10.1101/2024.08.23.609402 — bioengineering — Posted on 2024-08-26
1105 Reduction of SEM charging artefacts in native cryogenic biological samples.
Velazco, A.; Glen, T.; Klumpe, S.; Pennington, A.; Zhang, J.; Smith, J. L.; Glynn, C.; Bowles, W.; Kobylynska, M.; Fleck, R. A.; Naismith, J. H.; Kim, J. S.; Darrow, M. C.; Grange, M.; Kirkland, A. I.; Dumoux, M.
10.1101/2024.08.23.609373 — cell biology — Posted on 2024-08-26
1108 Therapeutically targeting the classical complement pathway with antisense oligonucleotides in Alzheimer's disease
Wang, Y.; Wu, T.; Gogineni, A.; Tsai, M.-C.; Kielpinski, L.; Mahajan, A.; Pandey, S.; Schachner, L.; Tran, J. C.; Wu, C.; Schauer, S.; Biever, A.; Boesen, S.; Li, M.; Munk, A.; Meilandt, W. J.; Elstrott, J.; Easton, A.; Gylling, H. M.; Hanson, J. E.
10.1101/2024.08.23.609240 — neuroscience — Posted on 2024-08-26
1109 Mechanistic modeling of cell viability assays with in silico lineage tracing
Mutsuddy, A.; Huggins, J. R.; Amrit, A.; Erdem, C.; Calhoun, J. C.; Birtwistle, M. R.
10.1101/2024.08.23.609433 — systems biology — Posted on 2024-08-26
1110 Increased Postprandial Metabolic Flexibility is Associated with Higher Body Fat Percentages in Healthy Young Adults
Foreman, N. A.; Rajwade, S.; Bluth, J.; Skoglund, L.; Letts, A. M.; DiPietro, L.; Ciarleglio, A.; Barberio, M.
10.1101/2024.08.23.609405 — physiology — Posted on 2024-08-26
1111 A tactile discrimination task to study neuronal dynamics in freely-moving mice
Heimburg, F.; Mari Saluti, N.; Timm, J.; Adlakha, A.; Castelanelli, M.; Klumpp, M.; Embray, L.; Both, M.; Draguhn, A.; Kuner, T.; Groh, A.
10.1101/2024.08.24.609326 — neuroscience — Posted on 2024-08-26
1112 Movement-independent representation of reward-predicting cues in the medial part of the primate premotor cortex
Sehara, K.; Kondo, M.; Hirayama, Y.; Ebina, T.; Takaji, M.; Watakabe, A.; Inoue, K.-i.; Takada, M.; Yamamori, T.; Matsuzaki, M.
10.1101/2024.08.24.609512 — neuroscience — Posted on 2024-08-26
1117 Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues
Rebollo, R.; Gerenton, P.; Cumunel, E.; Mary, A.; Sabot, F.; Burlet, N.; Gillet, B.; Hughes, S.; Siqueira Oliveira, D.; Goubert, C.; Fablet, M.; Vieira, C.; Lacroix, V.
10.1101/2023.05.27.542554 — bioinformatics — Posted on 2024-08-26
1118 ARTIC RSV amplicon sequencing reveals global RSV genotype dynamics.
Maloney, D. M.; Fernandes, G.; Jasim, S.; Williams, T.; Namugenyi, S.; Carr, M.; Meyer, J. R.; Sharma, A.; Marshal, L.; Nunley, B. E.; Xie, H.; Carvajal, M.; Kunerth, H. D.; Tanmoy, A.; O'Toole, A.; Weixler, A.; Lanter, K. R.; Gonzalez, G.; Sereewit, J.; Guevara, R.; Astbury, S.; Fanning, P. M.; Benitez, D.; Fernandez, J. C.; Cardenas, P.; Hare, D.; Greninger, A.; Williams, T.; Nebbia, G.; Fries, A. C.; McClure, P.; Roychoudhury, P.; Wang, X.; Saha, S.; Dewar, R.; Templeton, K. E.; Rambaut, A.
10.1101/2024.08.23.609324 — genomics — Posted on 2024-08-26
1119 The genetic architecture of cell-type-specific cis-regulation
Marand, A. P.; Jiang, L.; Gomez-Cano, F. A.; Minow, M. A. A.; Zhang, X.; Mendieta, J. P.; Luo, Z.; Bang, S.; Yan, H.; Meyer, C.; Schlegel, L.; Johannes, F.; Schmitz, R. J.
10.1101/2024.08.17.608383 — genetics — Posted on 2024-08-26
1122 Spatial Dynamics of the Developing Human Heart
Lazar, E.; Mauron, R.; Andrusivova, Z.; Foyer, J.; He, M.; Larsson, L.; Shakari, N.; Salas, S. M.; Avenel, C.; Sariyar, S.; Hansen, J. N.; Vicari, M.; Czarnewski, P.; Braun, E.; Li, X.; Bergmann, O.; Sylven, C.; Lundberg, E.; Linnarsson, S.; Nilsson, M.; Sundstrom, E.; Adameyko, I.; Lundeberg, J.
10.1101/2024.03.12.584577 — developmental biology — Posted on 2024-08-26
1123 Plasma triacylglycerol length and saturation level mark healthy aging groups in humans
Li, W. L.; Schomakers, B. V.; Weeghel, M. v.; Grevendonk, L.; Vaz, F. M.; Salomons, G. S.; Schrauwen, P.; Hoeks, J.; Gao, A. W.; Houtkooper, R. H.; Janssens, G. E.
10.1101/2024.08.22.609162 — developmental biology — Posted on 2024-08-26
1124 Epsins oversee smooth muscle cell reprogramming by influencing master regulators KLF4 and OCT4.
Wang, B.; Cui, K.; Zhu, B.; Dong, Y.; Wang, D.; Singh, B.; Wu, H.; Li, K.; Eisa-Beygi, S.; Sun, Y.; Wong, S.; Cowan, D. B.; Chen, Y.; Du, M.; Chen, H.
10.1101/2024.01.08.574714 — cell biology — Posted on 2024-08-26
1125 G1 length dictates H3K27me3 landscapes
Trouth, A.; Ravichandran, K.; Gafken, P.; Martire, S.; Boyle, G. E.; Veronezi, G. M. B.; La, V.; Namciu, S. J.; Banaszynski, L. A.; Sarthy, J. F.; Ramachandran, S.
10.1101/2023.12.05.570186 — molecular biology — Posted on 2024-08-26
1127 Cell-type-specific striatal modulation of amygdalar acetylcholine in salience assignment
Chen, A.; Li, Y.; Zhu, H.; Gu, H.; Weng, Y.; Ye, Q.; Guan, W.; Sun, Q.; Li, B.; Xu, F.; Deng, H.; Xiao, X.
10.1101/2024.07.30.605919 — neuroscience — Posted on 2024-08-26
1128 Expertise in reading visual Braille co-opts the reading network
Cerpelloni, F.; Van Audenhaege, A.; Matuszewski, J.; Gau, R.; Battal, C.; Falagiarda, F.; Op de Beeck, H.; Collignon, O.
10.1101/2024.05.08.593104 — neuroscience — Posted on 2024-08-26
1135 CIA: a Cluster Independent Annotation method to investigate cell identities in scRNA-seq data
Ferrari, I.; Battistella, M.; Vincenti, F.; Gobbini, A.; Marini, F.; Notarbartolo, S.; Costanza, J.; Biffo, S.; Grifantini, R. M.; Abrignani, S.; Galeota, E.
10.1101/2023.11.30.569382 — bioinformatics — Posted on 2024-08-26
1136 Basis of Glucose and Fructose Selectivity in Sugar Transport Proteins
Andersen, C. G.; Bavnhoj, L.; Brag, S.; Driller, J. H.; Pedersen, B. P.
10.1101/2024.07.19.604285 — biochemistry — Posted on 2024-08-26
1137 Non-canonical Wnt signaling triggered by WNT2B drives adrenal aldosterone production
Borges, K. S.; Little, D.; de Almeida Magalhaes, T.; Ribeiro, C.; Dumontet, T.; Lapensee, C.; Basham, K. J.; Seth, A.; Azova, S.; Guagliardo, N. A.; Barret, P. Q.; Berber, M.; O'Connell, A. E.; Turcu, A. F.; Lerario, A. M.; Mohan, D.; Rainey, W.; Carlone, D. L.; Hirschhorn, J.; Salic, A.; Breault, D.; Hammer, G. D.
10.1101/2024.08.23.609423 — genetics — Posted on 2024-08-26
1138 Exploitation of phylum-spanning omics resources reveals complexity in the nematode FLP signalling system and provides insights into flp-gene evolution
McCoy, C. J.; Wray, C.; Freeman, L.; Crooks, B. A.; Golinelli, L.; Marks, N. J.; Temmerman, L.; Beets, I.; Atkinson, L. E.; Mousley, A.
10.1101/2024.08.25.609560 — evolutionary biology — Posted on 2024-08-26
1139 The Regulatory Logic of Planarian Stem Cell Differentiation
Perez-Posada, A.; Garcia-Castro, H.; Emili, E.; Vanni, V.; Arias-Baldrich, C.; Frölich, S.; van Heeringen, S. J.; Kenny, N. J.; Solana, J.
10.1101/2024.08.23.608747 — systems biology — Posted on 2024-08-26
1141 Cellular and molecular networks of intercellular signaling in bone marrow hematopoiesis
Thomas, Z.; Wang, B.; Boohar, W.; Vergel, M.; Eerdeng, J.; Shon, D.; Elowitz, M. B.; Lu, R.
10.1101/2024.08.25.609544 — bioinformatics — Posted on 2024-08-26
1142 Bats from the Colombian Caribbean Reveal a new subtype of Influenza A (H18N12)
Echeverri, D. M.; Martinez-Bravo, C.; Gastelbondo-Pastrana, B.; Rivero, R. M.; Lopez, Y.; Hoyos, R.; Aleman, M.; Garay, E.; Bertel, V.; Arrieta, G.; Ramirez, J. D.; Mattar, S.
10.1101/2024.08.25.609627 — bioinformatics — Posted on 2024-08-26
1148 Deciphering plant-beneficial fungal interactions: Unravelling metabolic diversity that underpins communication between Laccaria bicolor and Trichoderma
Sivaprakasam Padmanaban, P. B.; Stange, P.; Weber, B.; Ghirardo, A.; Pritsch, K.; Karl, T.; Benz, J. P.; Rosenkranz, M.; Schnitzler, J.-P.
10.1101/2024.08.26.608944 — microbiology — Posted on 2024-08-26
1150 Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux
Chuang, K.-H.; Zhou, X. A.; Xia, Y.; Li, Z.; Qian, L.; Eeles, E.; Ngiam, G.; Fripp, J.; Coulson, E. J.
10.1101/2024.08.25.609536 — neuroscience — Posted on 2024-08-26
1151 Switch-like Gene Expression Modulates Disease Susceptibility
Aqil, A.; Li, Y.; Wang, Z.; Islam, S.; Russel, M.; Kunovac Kallak, T.; Saitou, M.; Gokcumen, O.; Masuda, N.
10.1101/2024.08.24.609537 — bioinformatics — Posted on 2024-08-26
1153 A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate
Brooks, E. R.; Moorman, A. R.; Bhattacharya, B.; Prudhomme, I.; Land, M.; Alcorn, H. L.; Sharma, R.; Pe'er, D.; Zallen, J. A.
10.1101/2024.08.25.609458 — developmental biology — Posted on 2024-08-26
1154 Fornix and Uncinate Fasciculus Support Metacognition-Driven Cognitive Offloading
Zheng, Y.; Bo, B.; Wang, D.; Liu, Y.; Gilbert, S. J.; Li, Y.; Kwok, S. C.
10.1101/2024.08.24.609527 — neuroscience — Posted on 2024-08-26
1155 Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood
Stefanovic, F.; Brown, L.; MacDonald, J.; Bammler, T. K.; Rinchai, D.; Nguyen, S.; Zeng, Y.; Shinkawa, V.; Adams, K.; Chaussabel, D.; Berthier, E.; Haack, A. J.; Theberge, A. B.
10.1101/2024.08.24.609519 — bioengineering — Posted on 2024-08-25
1158 Input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons
Topolski, M. A.; Gilmore, B. L.; Khondaker, R.; Michniak, J. A.; Studtmann, C.; Chen, Y.; Wagner, G. N.; Pozo-Aranda, A. E.; Farris, S.; Swanger, S. A.
10.1101/2024.08.23.607324 — neuroscience — Posted on 2024-08-25
1160 Exploring symbiotic legume-rhizobia relationships across tropical species
Rojas-Jimenez, K.; Morera-Huertas, J.; de Bedout-Mora, M.; Loria-Vinueza, B.; Zuniga-Orozco, A.; Molina-Mora, J. A.; Solis-Ramos, L.; Blanco, M. A.; Valverde-Barrantes, O. J.
10.1101/2024.08.23.609460 — plant biology — Posted on 2024-08-25
1167 A systematic evaluation of computational methods for cell segmentation
Wang, Y.; Zhao, J.; Xu, H.; Han, C.; Tao, Z.; Zhou, D.; Geng, T.; Liu, D.; Ji, Z.
10.1101/2024.01.28.577670 — bioinformatics — Posted on 2024-08-25
1168 Fibril Paint: a class of amyloid-targeting peptides
Pedrola, J. A.; Dekker, F. A.; Guttmann, K.; van Leeuwen, L. M.; Singh, S.; Mayer, G.; Garfagnini, T.; Friedler, A.; Rudiger, S. G. D.
10.1101/2024.08.25.609586 — biochemistry — Posted on 2024-08-25
1169 Integrated structural model of the palladin-actin complex using XL-MS, docking, NMR, and SAXS
Sargent, R.; Liu, D. H.; Yadav, R.; Glennenmeier, D.; Bradford, C. W.; Urbina, N.; Beck, M. R.
10.1101/2024.08.25.609580 — biochemistry — Posted on 2024-08-25
1170 Screening macrocyclic peptide libraries by yeast display allows control of selection process and affinity ranking
Linciano, S.; Mazzocato, Y.; Romanyuk, Z.; Vascon, F.; Soler, L. F.; Will, E.; Xing, Y.; Chen, S.; Kumada, Y.; Simeoni, M.; Scarso, A.; Cendron, L.; Heinis, C.; Angelini, A.
10.1101/2024.08.24.609237 — biochemistry — Posted on 2024-08-25
1171 New insights into the structure of cellulose in plant cell walls
Cresswell, R.; Deralia, P. K.; Yoshimi, Y.; Brown, S. P.; Dupree, R.; Dupree, P.
10.1101/2024.08.24.609305 — biochemistry — Posted on 2024-08-25
1173 Phylogenomics, Classification, and Lifestyle Evolution in Raft- and Nursery Web- Spiders (Araneae: Dolomedidae and Pisauridae)
Yu, K.-P.; Cheng, R.-C.; Haddad, C. R.; Tanikawa, A.; Pett, B. L.; Piacentini, L. N.; Jaeger, P.; Yip, H. Y.; Suzuki, Y.; Henrard, A.; Painting, C. J.; Vink, C. J.; Hebets, E. A.; Harvey, M. S.; Kuntner, M.
10.1101/2024.08.23.609317 — evolutionary biology — Posted on 2024-08-25
1174 Temperature and Pressure Shaped the Evolution of Antifreeze Proteins in Polar and Deep Sea Zoarcoid Fishes
Bogan, S. N.; Surendran, N.; Hotaling, S.; Desvignes, T.; Bista, I.; Lins, L. S. F.; Eilertsen, M. H.; Le Francois, N. R.; Algayer, T.; Hamilton, S. L.; Frandsen, P. B.; Hoffmann, F. G.; Kelley, J. L.
10.1101/2024.08.24.609455 — evolutionary biology — Posted on 2024-08-25
1176 Effectiveness of Exercise Intervention in Preventing Active Arthritis Exacerbation in an SKG Mouse Model of Rheumatoid Arthritis
Ozone, K.; Kumagai, T.; Arakawa, K.; Sugasawa, T.; Gu, W.; Kawabata, S.; Shimada, N.; Takahashi, H.; Yoneno, M.; Minegishi, Y.; Takahata, K.; Sato, M.; Oka, Y.; Kanemura, N.
10.1101/2024.08.25.609287 — molecular biology — Posted on 2024-08-25
1179 Identification of a mesodermal progenitor for the pro-definitive angio-hematopoietic lineage
Lazarov, T.; Loyher, P.-L.; Yang, H.; Choo, Z.-N.; Deng, Z.; Nowotschin, S.; Kuo, Y.-Y.; Zhou, T.; Alberdi-Gonzalez, A.; Stumm, R.; Mass, E.; Gomez Perdiguero, E.; Hadjantonakis, A.-K.; Geissmann, F.
10.1101/2024.08.24.609533 — immunology — Posted on 2024-08-25
1180 A Unified Atlas of T cell Glycophysiology
Izzati, F. N.; Choksi, H.; Giuliana, P.; Abd-Rabbo, D.; Elsaesser, H.; Blundell, A.; Affe, V.; Kannen, V.; Jame-Chenarboo, Z.; Schmidt, E.; Kuypers, M.; Avila, D. B.; Chiu, E. S. Y.; Badmaev, D.; Cui, H.; Matthews, J.; Mallevaey, T.; Macauley, M. S.; Brooks, D. G.; Edgar, L. J.
10.1101/2024.08.24.609521 — immunology — Posted on 2024-08-25
1181 Transitions in dynamical regime and neural mode underlie perceptual decision-making
Luo, T. Z.; Kim, T. D.; Gupta, D.; Bondy, A. G.; Kopec, C. D.; Elliott, V. A.; DePasquale, B.; Brody, C.
10.1101/2023.10.15.562427 — neuroscience — Posted on 2024-08-25
1183 TAF1-dependent transcriptional dysregulation underlies multiple sclerosis
Rodriguez-Lopez, C.; Hernandez, I. H.; Terron-Bautista, J.; Agirre, E.; Lozano-Munoz, D.; Pose-Utrilla, J.; Garcia-Ortiz, I.; Lucas-Santamaria, M.; Ruiz-Blas, I.; Gonzalez-Bermejo, M.; Ortega, M. C.; Chara, J. C.; Martinez, Z.; Perez-Cerda, F.; Fransen, N. L.; Martinez-Jimenez, M.; Sancho-Gonzalez, B.; Perez-Samartin, A.; Kabbe, M.; Zheng, C.; Casado-Barbero, M.; Santos-Galindo, M.; Borroto, A.; Alarcon, B.; Clemente, D.; Toma, C.; Matute, C.; Cortes-Ledesma, F.; Castelo-Branco, G.; Lucas, J. J.
10.1101/2024.08.23.609325 — neuroscience — Posted on 2024-08-25
1184 Coordinated cross-brain activity during accumulation of sensory evidence and decision commitment
Bondy, A. G.; Charlton, J. A.; Luo, T. Z.; Kopec, C. D.; Stagnaro, W. M.; Venditto, S. J. C.; Lynch, L.; Janarthanan, S.; Oline, S. N.; Harris, T. D.; Brody, C. D.
10.1101/2024.08.21.609044 — neuroscience — Posted on 2024-08-25
1187 Super-Enhancer Driven ZFP36L1 Promotes PD-L1 Expression in Infiltrative Gastric Cancer
Wei, X.; Liu, J.; Cheng, J.; Cai, W.; Xie, W.; Wang, K.; Lin, L.; Hou, J.; Cai, J.; Zhuo, H.
10.1101/2024.05.22.595316 — cancer biology — Posted on 2024-08-25
1188 Optimized Dosing and Delivery of Bacteriophage Therapy for Wound Infections
Lin, Y.-H.; Dharmaraj, T.; Chen, Q.; Echterhof, A.; Manasherob, R.; Zhang, L. J.; de Leeuw, C.; Peterson, N. A.; Stannard, W.; Li, Z.; Hajfathalian, M.; Hargil, A.; Martinez, H. A.; Pourtois, J.; Chang, T. H. W.; Blankenberg, F. G.; Amanatullah, D.; Chaudhuri, O.; Bollyky, P. L.
10.1101/2024.05.07.593005 — bioengineering — Posted on 2024-08-25
1189 Intrinsically Disordered Regions Define Unique Protein Interaction Networks in CHD Family Remodelers
Tabar, M. S.; Parsania, C.; Giardina, C.; Feng, Y.; Wong, A. C.; metierre, C.; Nagarajah, R.; Dhungel, B. P.; Rasko, J. E.; Bailey, C. G.
10.1101/2024.08.25.609601 — biochemistry — Posted on 2024-08-25
1194 Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health
Aranda-Diaz, A.; Vickers, E. N.; Murie, K.; Palmer, B.; Hathaway, N.; Gerlovina, I.; Boene, S.; Garcia-Ulloa, M.; Cistero, P.; Katairo, T.; Semakuba, F. D.; Nsengimaana, B.; Gwarinda, H.; Garcia-Fernandez, C.; Da Silva, C.; Datta, D.; Kiyaga, S.; Wiringilimaana, I.; Fekele, S. M.; Parr, J. B.; Conrad, M.; Raman, J.; Tukwasibwe, S.; Ssewanyana, I.; Rovira-Vallbona, E.; Tato, C. M.; Briggs, J.; Mayor, A.; Greenhouse, B.
10.1101/2024.08.22.609145 — genomics — Posted on 2024-08-25
1196 A CRISPR-Nonhomologous End-Joining-based strategy for rapid and efficient gene disruption in Mycobacterium abscessus
Zeng, S.; Ju, Y.; Alam, M. S.; Lu, Z.; Hameed, H. M. A.; Li, L.; Tian, X.; Fang, C.; Fang, X.; Ding, J.; Wang, X.; Hu, J.; Wang, S.; Zhang, T.
10.1101/2024.01.29.577284 — microbiology — Posted on 2024-08-25
1199 Ground nesting of soft eggs by extinct birds and a new parity mode switch hypothesis for the evolution of animal reproduction
Guimaraes, M. J.; Wang, J.; Zhang, X.; Sun, Q.; Cerqueira, M. F.; Chung, Y.-H.; Deng, R.; Guo, B.; Alpuim, P.; Ma, F.; Wang, X.; Yen, T.-C.
10.1101/2024.08.15.607182 — evolutionary biology — Posted on 2024-08-25
1201 Signal transduction pathways controlling Ins2 gene activity and β cell state transitions
Chu, J.; Sabbineni, B.; Cen, H. H.; Hu, X.; Sun, W. G.; Brownrigg, G. P.; Xia, Y. H.; Rogalski, J.; Johnson, J. D.
10.1101/2024.06.06.597838 — cell biology — Posted on 2024-08-25
1202 Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion
Murao, N.; Morikawa, R.; Seino, Y.; Shimomura, K.; Maejima, Y.; Ohno, T.; Yokoi, N.; Yamada, Y.; Suzuki, A.
10.1101/2024.08.15.608033 — cell biology — Posted on 2024-08-25
1204 Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
Kamel, W.; Ruscica, V.; Embarc-Buh, A.; R. de Laurent, Z.; Garcia-Moreno, M.; Demyanenko, Y.; Madhusudhan, M.; Iselin, L.; Järvelin, A.; Hannan, M.; Kitano, E.; Moore, S.; Merits, A.; Davis, I.; Mohammed, S.; Castello, A.
10.1101/2021.10.06.463336 — microbiology — Posted on 2024-08-25
1208 Disrupted stimulus encoding shapes tactile perception in autism.
Semelidou, O.; Gauvrit, T.; Vandromme, C.; Cornier, A.; Saint-Jean, A.; Le Feuvre, Y.; Ginger, M.; Frick, A.
10.1101/2024.08.08.607129 — neuroscience — Posted on 2024-08-25
1211 Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment
Mukherjee, A. K.; Dutta, S.; Singh, A.; Sharma, S.; Roy, S. S.; Sengupta, A.; Chatterjee, M.; Vinayagamurthy, S.; Bagri, S.; Khanna, D.; Verma, M.; Soni, D.; Budharaja, A.; Bhisade, S. K.; anand, V.; Perwez, A.; George, N.; Faruq, M.; Gupta, I.; Sabarinathan, R.; Chowdhury, S.
10.1101/2021.12.07.471419 — cancer biology — Posted on 2024-08-25
1214 Lightweight taxonomic profiling of long-read metagenomic datasets with Lemur and Magnet
Sapoval, N.; Liu, Y.; Curry, K.; Kille, B.; Huang, W.; Kokroko, N.; Nute, M. G.; Tyshaieva, A.; Dilthey, A. T.; Molloy, E.; Treangen, T. J.
10.1101/2024.06.01.596961 — bioinformatics — Posted on 2024-08-25
1216 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies
Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Markenscoff-Papadimitriou, E.; Reed, R. D.
10.1101/2024.02.09.579733 — genetics — Posted on 2024-08-25
1220 Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4+ T cell response
Chudnovskiy, A.; Castro, T. B.; Nakandakari-Higa, S.; Cui, A.; Lin, C.-H.; Sade-Feldman, M.; Phillips, B. K.; Pae, J.; Mesin, L.; Bortolatto, J.; Schweitzer, L. D.; Pasqual, G.; Lu, L.-F.; Hacohen, N.; Victora, G. D.
10.1101/2022.10.25.513771 — immunology — Posted on 2024-08-25
1224 Single-cell analysis of the somatic mutational landscape in human chondrocytes during aging and in osteoarthritis
Ren, P.; Zheng, C.; Pang, Y.; Sun, S.; Wang, Q.; Xu, W.; Lee, M.; Qiang, Y.; Lu, Z.; Zhou, M.; He, J.; Liu, N.-N.; Maslov, A. Y.; Dong, X.; Gao, J.; Zhang, C.; Vijg, J.
10.1101/2024.08.24.609506 — genomics — Posted on 2024-08-25
1225 Dynamic convergence of autism disorder risk genes across neurodevelopment
Fernandez Garcia, M.; Retallick-Townsley, K.; Pruitt, A.; Davidson, E.; Dai, Y.; Fitzpatrick, S. E.; Sen, A.; Cohen, S.; Livoti, O.; Khan, S.; Dossou, G.; Cheung, J.; Deans, P. J. M.; Wang, Z.; Huckins, L.; Hoffman, E.; Brennand, K.
10.1101/2024.08.23.609190 — genetics — Posted on 2024-08-24
1226 Transcriptomic analysis and high throughput functional characterization of human induced pluripotent stem cell derived sensory neurons
Truong, V.; Brougher, J.; Strassmaier, T.; Lu, I.; George, D.; Price, T. J.; Randolph, A.; Obergrussberger, A. R.; Haedo, R.; Fertig, N.; Walsh, P.
10.1101/2024.08.23.607310 — cell biology — Posted on 2024-08-24
1228 Brain structure and activity predicting cognitive maturation in adolescence
Zhu, J.; Garin, C. M.; Qi, X.-L.; Machado, A.; Wang, Z.; Ben Hamed, S.; Stanford, T. R.; Salinas, E.; Whitlow, C. T.; Anderson, A. W.; Zhou, X. M.; Calabro, F.; Luna, B.; Constantinidis, C.
10.1101/2024.08.23.608315 — neuroscience — Posted on 2024-08-24
1229 Gesture encoding in human left precentral gyrus neuronal ensembles
Vargas-Irwin, C. E.; Hosman, T.; Gusman, J. T.; Pun, T. K.; Simeral, J. D.; Singer-Clark, T.; Kapitonava, A.; Nicolas, C.; Shah, N. P.; Avansino, D.; Kamdar, F.; Williams, Z.; Henderson, J. M.; Hochberg, L. R.
10.1101/2024.08.23.608325 — neuroscience — Posted on 2024-08-24
1230 Structural Development of Speech Networks in Young Children at Risk for Speech Disorder
Curtis, M.; Bayat, M.; Garic, D.; Alfano, A.; Hernandez, M.; Curzon, M.; Bejarano, A.; Tremblay, P.; Graziano, P.; Dick, A. S.
10.1101/2024.08.23.609470 — neuroscience — Posted on 2024-08-24
1232 Phylogenomics, Classification, and Lifestyle Evolution in Raft- and Nursery web- Spiders (Araneae: Dolomedidae and Pisauridae)
Yu, K.-P.; Cheng, R.-C.; Haddad, C. R.; Tanikawa, A.; Pett, B. L.; Piacentini, L. N.; Jager, P.; Yip, H. Y.; Suzuki, Y.; Henrard, A.; Painting, C. J.; Vink, C. J.; Hebets, E. A.; Harvey, M. S.; Kuntner, M.
10.1101/2024.08.23.609317 — evolutionary biology — Posted on 2024-08-24
1233 OPA1 mediates cardiac function and metabolism: in silico and in vivo evidence
Fong-McMaster, C.; Pulente, S. M.; Kennedy, L.; Smith, T. K. T.; Myers, S.; Kanaan, M.; Karam, C.; Cope, M.; Lorenzen-Schmidt, I.; Goergen, C. J.; Fullerton, M. D.; Cuperlovic-Culf, M.; Mulvihill, E. E.; Harper, M.-E.
10.1101/2024.08.23.605375 — biochemistry — Posted on 2024-08-24
1234 Decoding protein glycosylation by an integrative mass spectrometry-based de novo sequencing strategy
Gao, J.; Chen, H.; Yin, H.; Chen, X.; Yang, Z.; Wang, Y.; Wu, J.; Tian, Y.; Shao, H.; Wen, L.; Zhou, H.
10.1101/2024.08.23.609376 — biochemistry — Posted on 2024-08-24
1235 Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing
Hazelbaker, D. Z.; Mehta, J. B.; McGinnis, C.; Santesmasses, D.; Bara, A. M.; Liang, X.; Biondi, T.; Fennell, T.; Homer, N.; Estes, B.; Xie, J.; Norouzi, D.; Molugu, K.; Amunugama, R.; Luo, C.; Amin, P.; Shi, X.; Cochrane, J.; Kumar, S.; Wang, J.; Bakalar, M. H.; Finn, J. D.; O'Connell, D. J.
10.1101/2024.08.23.609471 — genomics — Posted on 2024-08-24
1237 In vivo contribution of Cyp24a1 promoter vitamin D response elements
Meyer, M. B.; Lee, S. M.; Towne, J. M.; Cichanski, S. R.; Kaufmann, M.; Jones, G.; Pike, J. W.
10.1101/2024.08.23.609393 — genomics — Posted on 2024-08-24
1238 Understanding the Global Spread of Artemisinin Resistance: Insights from over 100K Plasmodium falciparum Samples
Balmer, A. J.; White, N. F. D.; Ünlü, E. S.; Lee, C.; Pearson, R. D.; Almagro-Garcia, J.; Ariani, C.
10.1101/2024.08.23.609367 — genomics — Posted on 2024-08-24
1240 Evolutionary adaptation under climate change: Aedes sp. demonstrates potential to adapt to warming
Couper, L. I.; Dodge, T. O.; Hemker, J. A.; Kim, B. Y.; Exposito-Alonso, M.; Brem, R. B.; Mordecai, E. A.; Bitter, M. C.
10.1101/2024.08.23.609454 — evolutionary biology — Posted on 2024-08-24
1246 LDB1 establishes multi-enhancer networks to regulate gene expression
Aboreden, N. G.; Lam, J. C.; Goel, V. Y.; Wang, S.; Wang, X.; Midla, S. C.; Quijano, A.; Keller, C. A.; Giardine, B. M.; Hardison, R. C.; Zhang, H.; Hansen, A. S.; Blobel, G.
10.1101/2024.08.23.609430 — molecular biology — Posted on 2024-08-24
1249 Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus
McGowen, K.; Funck, T.; Wang, X.; Zinga, S.; Wolf, I. D.; Akusobi, C.; Denkinger, C. M.; Rubin, E. J.; Sullivan, M. R.
10.1101/2024.08.23.609441 — microbiology — Posted on 2024-08-24
1250 Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins
Hill, N.; Matulina, L. M.; MacIntyre, C.; Hassani, M. A.; Thomas, S.; Luban, M.; Ward, I.; Abdalla, A.; Leong, J. M.; Garcia, B. L.; Lemieux, J. E.
10.1101/2024.08.23.609448 — microbiology — Posted on 2024-08-24
1252 Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
Roys, H.; Arykbayeva, A.; Friedman, S. K.; Gifford, G.; Palmer, E. R.; Rogers, A.; Tran, E. N. H.; Fry, L. G.; Weaver, A.; Bowlin, A. K.; Jones, M. D.; Eledge, M.; Boehme, K. W.; Naumiec, G. R.; Weinkopff, T.
10.1101/2024.08.23.605637 — microbiology — Posted on 2024-08-24
1254 Infection characteristics among Serratia marcescens capsule lineages.
Anderson, M. T.; Himpsl, S. D.; Kingsley, L. G.; Smith, S. N.; Bachman, M. A.; Mobley, H. L. T.
10.1101/2024.08.23.609398 — microbiology — Posted on 2024-08-24
1257 Tracing the genetic diversity of the bread wheat D genome
Wang, Z.; Wang, W.; He, Y.; Xie, X.; Yang, Z.; Zhang, X.; Niu, J.; Peng, H.; Yao, Y.; Xie, C.; Xin, M.; Hu, Z.; Sun, Q.; Ni, Z.; Guo, W.
10.1101/2024.08.23.609385 — evolutionary biology — Posted on 2024-08-24
1258 Chronic innate immune impairment and ZIKV persistence in the gastrointestinal tract during SIV infection in pigtail macaques
Tisoncik-Go, J.; Lewis, T. B.; Whitmore, L. S.; Voss, K.; Niemeyer, S.; Dai, J.; Kim, P.; Hubbell, K.; Iwayama, N.; Ahrens, C.; Wangari, S.; Murnane, R.; Edlefsen, P. T.; Guerriero, K. A.; Gale, M.; Fuller, D. H.; O'Connor, M.
10.1101/2024.08.23.609309 — immunology — Posted on 2024-08-24
1259 The chloroplast located HKT transporter plays an important role in sporophyte development in Physcomitrium patens
Yanez-Dominguez, C.; Macedo-Osorio, K. S.; Lagunas-Gomez, D.; Torres-Cifuentes, D. M.; Castillo-Gonzalez, J.; Zavala-Padilla, G. T.; Pantoja, O.
10.1101/2024.08.22.609226 — plant biology — Posted on 2024-08-24
1260 Gasdermin D deficiency attenuates development of ascending aortic dissections in a novel mouse model
Javed, M. J.; Howard, R. M.; Li, H.; Carrasco, L.; Dirain, M. L.; Su, G.; Cai, G.; Upchurch, G.; Jiang, Z.
10.1101/2024.08.22.609270 — physiology — Posted on 2024-08-24
1262 Mammalian PIEZO channels rectify anionic currents
Wijerathne, T. D.; Bhatt, A.; Jiang, W.; Luo, Y.; Lacroix, J. J.
10.1101/2024.08.23.609388 — biophysics — Posted on 2024-08-24
1265 Identification of an intrinsically disordered region (IDR) in arginyltransferase 1 (ATE1)
Cartwright, M.; Parakra, R.; Oduwole, A.; Zhang, F.; Deredge, D. J.; Smith, A. T.
10.1101/2024.08.23.609426 — biochemistry — Posted on 2024-08-24
1266 Poly-alanine-tailing is a modifier of neurodegeneration caused by Listerin mutation
Hung, H.-C.; Costas-Insua, C.; Holbrook, S. E.; Stauffer, J. E.; Martin, P. B.; Müller, T. A.; Schroeder, D. G.; Kigoshi-Tansho, Y.; Xu, H.; Rudolf, R.; Cox, G. A.; Joazeiro, C.
10.1101/2024.08.24.608776 — biochemistry — Posted on 2024-08-24
1267 De novo designed inhibitor confers protection against lethal toxic shock
Ragotte, R. J.; Liang, H.; Berman, J. M.; Gloegl, M.; Schramek, D.; Melnyk, R.; Baker, D.
10.1101/2024.08.23.608890 — microbiology — Posted on 2024-08-24
1268 The transcription factor RIP140 regulates interferon γ signaling in breast cancer
Jalaguier, S.; Kuehn, A.; Petitpas, C.; Dulom, A.; Jacquemont, R.; Assi, C.; Sixou, S.; Jeschke, U.; Colinge, J.; Cavailles, V.
10.1101/2024.02.15.580503 — cancer biology — Posted on 2024-08-24
1271 Adhesive and mechanical properties of the glue produced by 25 Drosophila species
Monier, M.; Lorenzi, J.-N.; Narasimha, S.; Borne, F.; Contremoulins, V.; Mevel, L.; Petit, R.; El Hachem, Y.; Graner, F.; Courtier-Orgogozo, V.
10.1101/2024.05.08.593221 — biophysics — Posted on 2024-08-24
1273 Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies
Lages, C. F.; Nicoleti, V. Y.; Correa, M. R.; Mausbach, P.; Ramos, F. C.; Araujo, E.; Nascimento, A. Z.; Miqueles, E. X.
10.1101/2024.08.22.609235 — bioinformatics — Posted on 2024-08-24
1275 Basis of Glucose Selectivity in Sugar Transport Proteins
Andersen, C. G.; Bavnhoj, L.; Brag, S.; Driller, J. H.; Pedersen, B. P.
10.1101/2024.07.19.604285 — biochemistry — Posted on 2024-08-24
1277 Assessing Autophagy Flux in Glioblastoma Temozolomide Resistant Cells
Clark, C.; Barzegar-Behrooz, A.; Cordani, M.; Shojaei, S.; Ghavami, S.
10.1101/2024.08.09.607348 — molecular biology — Posted on 2024-08-24
1278 Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
Salgueiro, V.; Bertol, J.; Gutierrez, C.; Serrano-Mestre, J. L.; Ferrer-Luzon, N.; Palacios, A.; Pasquina-Lemonche, L.; Espalliat, A.; Lerma, L.; Weinrick, B.; Lavin, J. L.; Elortza, F.; Azkalgorta, M.; Prieto, A.; Buendia-Nacarino, P.; Luque-Garcia, J. L.; Neyrolles, O.; Cava, F.; Hobbs, J.; Sanz, J.; Prados-Rosales, R.
10.1101/2023.11.19.567727 — microbiology — Posted on 2024-08-24
1279 The transition from a non-westernized to westernized gut microbiome in Indian-Immigrants and Indo-Canadians is associated with dietary acculturation
D'Aloisio, L. D.; Ballal, M.; Ghosh, S.; Haskey, N.; Abulizi, N.; Karimianghadim, R.; Liu, C.; Sruthi, P.; Nagarajan, L.; Vasudevan, S.; Shetty, V.; Purandare, M.; Bhaumik, U.; Howlader, D. R.; Pakpour, S.; Barnett, J.; Gibson, D. L.
10.1101/2024.03.04.582285 — microbiology — Posted on 2024-08-24
1282 Resilience of A Learned Motor Behavior After Chronic Disruption of Inhibitory Circuits
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2024-08-24
1283 Coordinated cross-brain activity during accumulation of sensory evidence and decision commitment
Bondy, A. G.; Charlton, J. A.; Luo, T. Z.; Kopec, C. D.; Stagnaro, W. M.; Venditto, S. J. C.; Lynch, L.; Janarthanan, S.; Oline, S. N.; Harris, T. D.; Brody, C. D.
10.1101/2024.08.21.609044 — neuroscience — Posted on 2024-08-24
1284 Conformational Ensembles Reveal the Origins of Serine Protease Catalysis
Du, S.; Kretsch, R. C.; Parres-Gold, J.; Pieri, E.; Cruzeiro, V. W. D.; Zhu, M.; Pinney, M. M.; Yabukarski, F.; Schwans, J. P.; Martinez, T. J.; Herschlag, D.
10.1101/2024.02.28.582624 — biophysics — Posted on 2024-08-24
1285 Lipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome
Becker, A. P.; Biletch, E.; Kennelly, J. P.; Julio, A. R.; Villanueva, M.; Nagari, R.; Turner, D. W.; Burton, N. R.; Fukuta, T.; Cui, L.; Xiao, X.; Hong, S.-G.; Mack, J. J.; Tontonoz, P.; Backus, K.
10.1101/2024.08.20.608660 — biochemistry — Posted on 2024-08-24
1288 Cell fate specification and conversion generate foveolar cone subtype patterning in human retinal organoids
Hussey, K.; Eldred, K.; Guy, B.; Santiago, C.; Glass, I.; Reh, T. A.; Blackshaw, S.; Goff, L.; Johnston, R. J.
10.1101/2023.01.28.526051 — developmental biology — Posted on 2024-08-24
1292 Effects of early life stress paired with adolescent alcohol consumption on two-bottle choice alcohol drinking behaviors in mice
Perry, T. W.; Carvour, H. M.; Reichert, A. N.; Sneddon, E. A.; Roemer, C. A. E. G.; Gao, Y. Y.; Schuh, K. M.; Shand, N. A.; Quinn, J. J.; Radke, A. K.
10.1101/2023.01.21.524642 — neuroscience — Posted on 2024-08-24
1297 The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas
Laurenge, A.; Pugliese, P.; Richard, Q.; Mathon, B.; Jouannet, S.; Hayat, Y.; Scuderi, S.; Marijon, P.; Labreche, K.; Alentorn, A.; Verreault, M.; Idbaih, A.; Birzu, C.; Huillard, E.; Pottier, N.; Aurore Desmons, A. D.; Fayache, I.; Kaas, G. A.; Kingsley, P. J.; Marnett, L. J.; Duplus, E.; El-Habr, E.; Salas, L. A.; Mokhtari, K.; Tran, S.; Touat, M.; Bielle, F.; Suva, M. L.; Iavarone, A.; Ceccarelli, M.; Mallat, M.; Sanson, M.; Castro-Vega, L. J.
10.1101/2024.08.23.608811 — cancer biology — Posted on 2024-08-23
1301 BGC Atlas: A Web Resource for Exploring the Global Chemical Diversity Encoded in Bacterial Genomes
Bagci, C.; Nuhamunada, M.; Goyat, H.; Ladanyi, C.; Sehnal, L.; Blin, K.; Kautsar, S. A.; Tagirdzhanov, A.; Gurevich, A.; Mantri, S.; von Mering, C.; Udwary, D.; Medema, M. H.; Weber, T.; Ziemert, N.
10.1101/2024.08.23.609335 — bioinformatics — Posted on 2024-08-23
1303 DEK-rRNA interactions regulate ribosome biogenesis and stress response
Xu, N.; Chen, K.; Prell, M.; Liang, P.; Yang, S.; Guo, S.; Lu, Y.; Dorle, S.; Idaghdour, S.; Kappes, F.
10.1101/2024.08.23.609341 — biochemistry — Posted on 2024-08-23
1304 The Transcription Factor Binding Landscape of Mouse Development
Nordin, A.; Zambanini, G.; Jonasson, M. E.; Weiss, T.; van de Grift, Y.; Pagella, P.; Cantu, C.
10.1101/2024.08.23.609315 — genomics — Posted on 2024-08-23
1306 Significant and persistent carryover effects in Scots pine
Perry, A.; Beaton, J. K.; Stockan, J. A.; Iason, G. R.; Cottrell, J. E.; Cavers, S.
10.1101/2024.08.23.609343 — ecology — Posted on 2024-08-23
1311 The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin
Grossi, E.; Nguyen, C. B.; Carcamo, S.; Moran, S.; Kirigin Callau, V.; Filipescu, D.; Hasson, D.; Bernstein, E.
10.1101/2024.08.23.609212 — molecular biology — Posted on 2024-08-23
1313 Determining the culturability of the bovine rumen bacterial and archaeal microbiota
Buckner, A. M.; Glendinning, L.; Palma Hidalgo, J. M.; van Munster, J. M.; Stevens, M.; Watson, M.; Newbold, C. J.
10.1101/2024.08.23.608987 — microbiology — Posted on 2024-08-23
1318 Expanding the biotechnological scope of metabolic sensors through computation-aided designs
Orsi, E.; Schulz-Mirbach, H.; Cotton, C. A. R.; Satanowski, A.; Petri, H.; Arnold, S. L.; Grabarczyk, N.; Verbakel, R.; Jensen, K. S.; Donati, S.; Paczia, N.; Glatter, T.; Kueffner, A. M.; Chotel, T.; Schillmueller, F.; De Maria, A.; He, H.; Lindner, S. N.; Noor, E.; Bar-Even, A.; Erb, T. J.; Nikel, P. I.
10.1101/2024.08.23.609350 — synthetic biology — Posted on 2024-08-23
1319 Air Pocket for a Non-Air-Breathing Fish: Developing Respirometry Methodology for the critically endangered Delta Smelt
Kwan, G. T.; Mauduit, F.; Zillig, K. W.; Yanagitsuru, Y. R.; Baird, S. E.; Cocherell, D. E.; Fangue, N. A.
10.1101/2024.08.23.609307 — physiology — Posted on 2024-08-23
1323 A coregulatory influence map of glioblastoma heterogeneity and plasticity - From cells in vitro to tumors and back again
Bernhard, C.; Geles, K.; Pawlak, G.; Dhifli, W.; Dispot, A.; Dusol, J.; Kondratova, M.; Martin, S.; Messe, M.; Reita, D.; Tulasne, D.; Van Seuningen, I.; Entz-Werle, N.; Ciafre, S.-A.; Dontenwill, M.; Elati, M.
10.1101/2024.08.23.609303 — cancer biology — Posted on 2024-08-23
1324 SpatialLeiden - Spatially-aware Leiden clustering
Müller-Bötticher, N.; Sahay, S.; Eils, R.; Ishaque, N.
10.1101/2024.08.23.609349 — bioinformatics — Posted on 2024-08-23
1325 Accurate antibody loop structure prediction enables zero-shot design of target-specific antibodies
Bang, Y.; Choi, Y.-A.; Gu, J.; Kwon, S.; Lee, D.; Lee, M. S.; Lee, S. J.; Lim, J.; Maeng, J. Y.; Nam, J.; Noh, J.; Oh, H.; Park, S.-Y.; Park, T.; Seo, S.; Seok, C.; Song, M. Y.; Won, J.; Woo, H.; Yang, J.; Yoon, M. J.; Bae, W.; Kim, J.; Lee, D.; Lee, J.; Lee, Y.; Yu, H.
10.1101/2024.08.23.609114 — bioengineering — Posted on 2024-08-23
1328 ARTIC RSV amplicon sequencing reveals global RSV genotype dynamics.
Maloney, D. M.; Fernandes, G.; Jasim, S.; Williams, T.; Namugenyi, S.; Carr, M.; Meyer, J. R.; Sharma, A.; Marshal, L.; Nunley, B. E.; Xie, H.; Carvajal, M.; Kunerth, H. D.; O'Toole, A.; Weixler, A.; Lanter, K. R.; Gonzalez, G.; Sereewit, J.; Guevara, R.; Astbury, S.; Fanning, P. M.; Benitez, D.; Fernandez, J. C.; Cardenas, P.; Hare, D.; Greninger, A.; Williams, T.; Nebbia, G.; Fries, A. C.; McClure, P.; Roychoudhury, P.; Wang, X.; Saha, S.; Dewar, R.; Templeton, K. E.; Rambaut, A.
10.1101/2024.08.23.609324 — genomics — Posted on 2024-08-23
1329 Inferring plant community phenology via bee-collected pollen
Wizenberg, S. B.; Pepinelli, M.; Do, B. N.; Moubony, M.; Tamashekan, D.; Conflitti, I. M.; Zayed, A.
10.1101/2024.08.23.609319 — ecology — Posted on 2024-08-23
1330 Gaps in the global protection of terrestrial genetic diversity
Schultz, J. T.; Geldmann, J.; Theodoridis, S.; Nogues-Bravo, D.
10.1101/2024.08.23.609342 — ecology — Posted on 2024-08-23
1332 FGF9 treatment reduces off-target chondrocytes from iPSC-derived kidney organoids
Joris, V.; Schumacher, A.; Marks, P.; Eischen-Loges, M.; van Griensven, M.; LaPointe, V.
10.1101/2024.08.23.609318 — cell biology — Posted on 2024-08-23
1335 Odoribacter splanchnicus mitigates Salmonella-induced gut inflammation and its associated pathogenesis via its secreted bacteriocin
Hajra, D.; Mukherjee, D.; Vij, R.; Rajmani, R. S.; Dadireddy, V.; Das, D.; Hussain, T.; Ganji, M.; Tatu, U.; Chakravortty, D.
10.1101/2024.08.23.609322 — microbiology — Posted on 2024-08-23
1337 Tactile Mechanisms and Afferents Underlying the Rat Pup Transport Response
Ni, Z.; Neifert, C.; Rosete, A.; Albeely, A. M.; Yang, Y.; Pratelli, M.; Brecht, M.; Clemens, A. M.
10.1101/2024.08.23.609194 — neuroscience — Posted on 2024-08-23
1338 Regulation of plant metabolism under elevated CO2
Shokouhi, D.; Hernandez, J. S.; Walther, D.; Kepp, G.; Schwenkert, S.; Leister, D.; Gremmels, J.; Zuther, E.; Alpers, J.; Naegele, T.; Heyer, A. G.
10.1101/2024.08.23.609313 — plant biology — Posted on 2024-08-23
1340 In vivo Antibody Painting for Next Generation Weight Loss Drugs
Kitahara, K.; Rondon, A.; Miller, E.; Mak, H. H.; Loas, A.; Pentelute, B. L.
10.1101/2024.08.22.609257 — bioengineering — Posted on 2024-08-23
1343 The applicability of Regional Red List assessments for soil invertebrates: First assessment of five native earthworm species in Canada
Phillips, H. R. P.; Brown, G. G.; James, S. W.; Mathieu, J.; Reynolds, J. W.; Dharmasiri, M. E.; Singer, C. L.; Briones, M. J. I.; Procter, H. C.; Cameron, E. K.
10.1101/2024.08.23.608777 — ecology — Posted on 2024-08-23
1347 Human melanoma cell lines that possess wild-type BRAF alleles but are dependent on ERBB4 and ERBB2
Dwivedi, V.; Lucas, L. M.; Cooke, R.; Davis, J.; Wilson, E.; Scott, M.; O'Daniel, K.; Dion, C.; Kerley, J.; Zelan, M.; DeFeo, N.; Huffman, V.; Ingrao, M. N.; Riese, D. J.
10.1101/2024.08.22.609260 — cancer biology — Posted on 2024-08-23
1350 Photo-induced changes in tissue stiffness alter epithelial budding morphogenesis in the embryonic lung
Peak, K. E.; Rajaguru, P.; Khan, A.; Gleghorn, J. P.; Obaid, G.; Ferruzzi, J.; Varner, V. D.
10.1101/2024.08.22.609268 — bioengineering — Posted on 2024-08-23
1355 Regulation of angiogenesis by signal sequence-derived peptides
Ghim, M.; Wei, L.; Jung, J.-J.; The, E.; Kukreja, G.; Neishabouri, A.; Ahmad, A.; Raza, M. Z.; Golbazi, A.; Hedayatyanfard, K.; Nie, L.; Zhang, J.; Sadeghi, M. M.
10.1101/2024.08.22.609269 — cell biology — Posted on 2024-08-23
1359 Bidirectional locomotion induces unilateral limb adaptations
Hardesty, R. L.; Motjabavi, H.; Gemoets, D. E.; Wolpaw, J. R. L.
10.1101/2024.08.22.609228 — neuroscience — Posted on 2024-08-23
1361 Remodelling of the glycome of B-cell precursor acute lymphoblastic leukemia cells developing drug-tolerance
Oliveira, T.; Zhang, M.; Chen, C.-W.; Packer, N.; von Itzstein, M.; Heisterkamp, N.; Kolarich, D.
10.1101/2024.08.22.609211 — cancer biology — Posted on 2024-08-23
1365 Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies
Lages, C. F.; Nicoleti, V. Y.; Correa, M. R.; Mausbach, P.; Ramos, F. C.; Araujo, E.; Nascimento, A. Z.; Miqueles, E. X.
10.1101/2024.08.22.609235 — bioinformatics — Posted on 2024-08-23
1366 A modular encapsulation system for precision delivery of proteins, nucleic acids and therapeutics
Luong, T. D.; Martel, N.; Rae, J.; Lo, H. P.; Lim, Y.-W.; Wu, Y.; McMahon, K.-A.; Fletcher, N.; Thurecht, K. J.; Johnston, A. P. R.; Ariotti, N.; Hall, T. E.; Parton, R. G.
10.1101/2024.08.22.607124 — bioengineering — Posted on 2024-08-23
1371 Large-scale manipulation of radial positioning does not affect most aspects of genome organization
Guetta, M.; Kariti, H.; Sherman, L.; Israitel, L.; Tel-Paz, M.; Avidan, N.; Shemer, R.; Kaplan, N.
10.1101/2024.08.22.609170 — genomics — Posted on 2024-08-23
1372 Contribution of brain intrinsic branched-chain amino acid metabolismin a novel mouse model of maple syrup urine disease
Kuhs, A. C.; Ohl, L.; Thurston, T.; Singh, J.; Bhuyan, S.; Grandinette, S.; Xu, J.; Siemsgluess, S. A.; Jakher, Y.; Ahrens-Nicklas, R. C.
10.1101/2024.08.22.609255 — genetics — Posted on 2024-08-23
1375 Blue light toxicity drives the gut microbiota-mediated lipid accumulation in Drosophila
Takada, Y.; Ichinose, T.; Fuse, N.; Saito, K.; Ikeda-Ohtsubo, W.; Tanimoto, H.; Hori, M.
10.1101/2024.08.22.608892 — evolutionary biology — Posted on 2024-08-23
1377 Leveraging Chlorination-Based Mechanism for Resolving Subcellular Hypochlorous Acid
Tang, F. K.; Tucker, L.; Nadiveedhi, M. R.; Hladun, C.; Morse, J.; Ali, M.; Payne, N.; Schmidt, M.; Leung, K.
10.1101/2024.08.22.609247 — cell biology — Posted on 2024-08-23
1378 Nociceptor Neurons Control Pollution-Mediated Neutrophilic Asthma
Wang, J.-C.; Crosson, T.; Reza Nikpoor, A.; Gupta, S.; Rafei, M.; Talbot, S.
10.1101/2024.08.22.609202 — immunology — Posted on 2024-08-23
1379 Proton pump inhibitors modulate esophageal epithelial barrier function and crosstalk with eosinophils
Gautam, R.; Lal, M.; Carroll, M. C.; Mrozek, Z.; Trachsel, T.; Beers, J.; Ruffner, M. A.
10.1101/2024.08.22.609219 — immunology — Posted on 2024-08-23
1380 Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection
Smyth, D. J.; Hodge, S.; Ong, N.; Richards, J.; Colomb, F.; Shek, V.; Frangova, T.; McSorley, H. J.
10.1101/2024.08.22.609138 — immunology — Posted on 2024-08-23
1382 SERS Analysis Of Sialic Acid In Single Dendritic Cells Within The Tumor Microenvironment
Xingrui, L.; Lingling, M.; Xiaofei, Y.; Nian, W.; Shiyu, B.; Qiongzhen, Z.; Yu, Y.; Weidong, H.; Zhengding, S.; Jinyao, L.
10.1101/2024.08.22.608950 — immunology — Posted on 2024-08-23
1383 Breastmilk IgG engages the neonatal immune system to instruct host-microbiota mutualism
Shenoy, M. K.; Rico, D.; Gordon, S.; Milburn, L.; Schwensen, J.; Caban, M.; Koch, M. A.
10.1101/2024.08.23.609293 — immunology — Posted on 2024-08-23
1385 Anxiety and risk-taking behavior maps onto opioid and alcohol polysubstance consumption patterns in male and female mice
Patarino, M.; Wang, Z. C.; Wong, K.; Lee, S. J.; Skillen, E.; Nag, R.; Baskin, B.; Schindler, A. G.
10.1101/2024.08.22.609245 — neuroscience — Posted on 2024-08-23
1387 Nageotte nodules in human DRG reveal neurodegeneration in painful diabetic neuropathy
Shiers, S.; Mazhar, K.; Wangzhou, A.; Haberberger, R. V.; Lesnak, J. B.; Sankaranarayanan, I.; Tavares-Ferreira, D.; Cervantes, A.; Funk, G.; Horton, P.; Vines, E.; Dussor, G.; Price, T. J.
10.1101/2024.08.22.609215 — neuroscience — Posted on 2024-08-23
1389 Two residues reprogram immunity receptor kinases to signal in nitrogen-fixing symbiosis
Tsitsikli, M.; Simonsen, B. W.; Larsen, M. M.; Andersen, C. G.; Gysel, K.; Lironi, D.; Kronauer, C.; Rubsam, H.; Luu, T.-B.; Hansen, S. B.; Kaya, G.; Stougaard, J.; Andersen, K. R.; Radutoiu, S.
10.1101/2024.08.22.609144 — plant biology — Posted on 2024-08-23
1390 VRS5 (HvTB1) binds to the promoter of tillering and floral homeotic genes to regulate their expression
Winkelmolen, T.; Colleoni, P.; Moscou, M. J.; hoseinzadeh, p.; Oldach, K.; Schmidt, R.-C.; Immink, R. G. H.; van Esse, G. W.
10.1101/2024.08.22.609225 — plant biology — Posted on 2024-08-23
1393 CDK4/6 inhibitors promote senescence-associated lysosomal alterations and enhance sensitivity to lysosomotropic agents in breast cancer
Nehme, J.; Massen, S.; Bravaccini, S.; Zanoni, M.; Gianni, C.; De Giorgi, U.; Soto-Gamez, A.; Altulea, A.; Gheorghe, T.; Wang, B.; Demaria, M.
10.1101/2024.08.22.609150 — cancer biology — Posted on 2024-08-23
1394 Multiplexed Glycan Immunofluorescence Identification of Pancreatic Cancer Cell Subpopulations in Both Tumor and Blood Samples
Binkowski, B.; Klamer, Z.; Gao, C.; Staal, B.; Repesh, A.; Tran, H.-L.; Brass, D. M.; Bartlett, P.; Gallinger, S.; Blomqvist, M.; Morrow, J. B.; Allen, P.; Shi, C.; Singhi, A.; Brand, R.; Huang, Y.; Hostetter, G.; Haab, B. B.
10.1101/2024.08.22.609143 — cancer biology — Posted on 2024-08-23
1395 Virtual Clinical Trials of BMP4 Differentiation Therapy: Digital Twins to Aid Glioblastoma Trial Design
Harbour, N.; Curtin, L.; Hubbard, M. E.; Jackson, P. R.; Rani, V.; Carrano, A.; Farias, V. d. A.; Kenchappa, R.; Quinones-Hinojosa, A.; Owen, M.; Swanson, K. R.
10.1101/2024.08.22.609156 — cancer biology — Posted on 2024-08-23
1396 Microenvironment T-Type calcium channels regulate neuronal and glial processes to promote glioblastoma growth
Dube, C. J.; Zhang, Y.; Saha, S.; Lai, M.; Gibert, M. K.; Escalante, M.; Hudson, K.; Wong, D.; Marcinkiewicz, P.; Yener, U.; Sun, Y.; Xu, E.; Sorot, A.; Mulcahy, E.; Kefas, B. A.; Hanif, F.; Guessous, F.; Patel, M. K.; Schiff, D.; Zong, H.; Purow, B. W.; Holland, E.; Sonkusare, S. K.; Sontheimer, H.; Abounader, R.
10.1101/2024.08.22.609229 — cancer biology — Posted on 2024-08-23
1400 PBAE-PEG based lipid nanoparticles for lung cell-specific gene delivery
Liu, B.; Sajiki, Y.; Sridharan, A.; Stuart, W.; Cui, X.; Siefert, M.; Araki, K.; Ziady, A.; Shi, D.; Whitsett, J. A.; Maeda, Y.
10.1101/2024.08.22.608643 — bioengineering — Posted on 2024-08-23
1401 Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations
Aw, W. Y.; Sawhney, A.; Rathod, M.; Whitworth, C. P.; Doherty, E. L.; Madden, E.; Lu, J.; Westphal, K.; Stack, R. N.; Polacheck, W. J.
10.1101/2024.08.22.609165 — bioengineering — Posted on 2024-08-23
1404 3D scanning measurement method for seed size research
Malik-Roffa, H.; Malik, T.; Tozser, D.; Tothmeresz, B.
10.1101/2024.08.22.609234 — ecology — Posted on 2024-08-23
1406 Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer
Kaivola, J.; Punovuori, K.; Chastney, M. R.; Miroshnikova, Y. A.; Bertillot, F.; Abdo, H.; Krautgasser, F.; Di Franco, J.; Conway, J. R. W.; Follain, G.; Hagstrom, J.; Makitie, A.; Irjala, H.; Ventela, S.; Hamidi, H.; Scita, G.; Cerbino, R.; Wickstrom, S. A.; Ivaska, J.
10.1101/2024.08.22.609159 — cell biology — Posted on 2024-08-23
1407 PI(4)P recruits CIDE proteins to promote the formation of unilocular lipids droplets
Wu, J.; Gao, M.; Wu, X.; Liu, Y.; Du, X.; Liang, Y.; Ma, C.; Li, P.; Chen, F.-J.; Yang, H.
10.1101/2024.08.22.609036 — cell biology — Posted on 2024-08-23
1408 Transmembrane channel-like 4 and 5 proteins at microvillar tips are potential ion channels and lipid scramblases
Ebrahim, S.; Ballesteros, A.; Zheng, W. S.; Mukherjee, S.; Hu, G.; Weng, W.-H.; Montgomery, J. W.; Agyemang, Y.; Cui, R.; Sun, W.; Krystofiak, E.; Foster, M. P.; Sotomayor, M.; Kachar, B.
10.1101/2024.08.22.609173 — cell biology — Posted on 2024-08-23
1412 Tracking clonal evolution of drug resistance in ovarian cancer patients by exploiting structural variants in cfDNA
Williams, M. J.; Vazquez-Garcia, I.; Tam, G.; Wu, M.; Varice, N.; Havasov, E.; Shi, H.; Satas, G.; Lees, H. J.; Lee, J.; Myers, M. A.; Zatzman, M.; Rusk, N.; Ali, E.; Shah, R. H.; Berger, M. F.; Mohibullah, N.; Lakhman, Y.; Chi, D. S.; Abu-Rustum, N. R.; Aghajanian, C.; McPherson, A.; Zamarin, D.; Loomis, B.; Weigelt, B.; Friedman, C. F.; Shah, S. P.
10.1101/2024.08.21.609031 — cancer biology — Posted on 2024-08-23
1414 Identifying novel chemical matter against the Chikungunya virus nsP3 macrodomain through crystallographic fragment screening
Aschenbrenner, J. C.; Godoy, A. S.; Fairhead, M.; Tomlinson, C. W. E.; Winokan, M.; Balcomb, B. H.; Capkin, E.; Chandran, A. V.; Golding, M.; Koekemoer, L.; Lithgo, R. M.; Marples, P. G.; Ni, X.; Thompson, W.; Wild, C.; Xavier, M.-A. E.; Fearon, D.; von Delft, F.
10.1101/2024.08.23.609196 — biochemistry — Posted on 2024-08-23
1415 Pemphigus vulgaris autoantibodies induce an ER stress response
Hoffman, C. L.; Bharathan, N. K.; Shibata, Y.; Giang, W.; Gudjonsson, J. E.; Seykora, J. T.; Prouty, S. M.; Payne, A. S.; Kowalczyk, A. P.
10.1101/2024.08.22.608849 — cell biology — Posted on 2024-08-23
1416 DNA methylation protects cancer cells against non-canonical senescence
Chen, X.; Yamaguchi, K.; Rodgers, B.; Goerhig, D.; Vindrieux, D.; Lahaye, X.; Nolot, M.; Ferry, L.; Dubus, P.; Miura, F.; Ito, T.; Manel, N.; Bernard, D.; Defossez, P.-A.
10.1101/2024.08.23.609297 — molecular biology — Posted on 2024-08-23
1417 Reply to: Eigenmodes of the brain: revisiting connectomics and geometry
Pang, J. C.; Aquino, K. M.; Oldehinkel, M.; Robinson, P. A.; Fulcher, B. D.; Breakspear, M.; Fornito, A.
10.1101/2024.08.21.608487 — neuroscience — Posted on 2024-08-23
1419 Exploring the uncharted: Novel potential filariasis vectors unveiled in Sri Lanka
Nimalrathna, S. U.; Amarasiri, C.; Aluthge, K.; Mallawarachchi, C.; Chandrasena, N.; de Silva, N.; de Silva, N.; Kimber, M.; Harischandra, H.
10.1101/2024.08.23.609308 — zoology — Posted on 2024-08-23
1420 Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis
Ojo, B. A.; Heo, L.; Fox, S. R.; Waddell, A.; Moreno-Fernandez, M. E.; Gibson, M.; Tran, T.; Dunn, A. L.; Elknawy, E. I. A.; Saini, N.; Lopez-Rivera, J. A.; Divanovic, S.; de Jesus Perez, V. A.; Rosen, M. J.
10.1101/2024.08.22.609271 — physiology — Posted on 2024-08-23
1421 Removal of the catalytic subunit of DNA-protein kinase in the proximal tubules promotes DNA and tubular damage during kidney injury
Swanson, M.; Yun, J.; Collier, D. M.; Challagundla, L.; Dogan, M.; Kuscu, C.; Garrett, M. R.; Regner, K. R.; Chung, J. H.; Park, F.
10.1101/2024.08.22.609216 — physiology — Posted on 2024-08-23
1422 Polyploid cancer cells reveal signatures of chemotherapy resistance
Schmidt, M. J.; Naghdloo, A.; Prabakar, R. K.; Kamal, M.; Cadaneanu, R.; Garraway, I. P.; Lewis, M.; Aparicio, A.; Kuhn, P.; Pienta, K. J.; Amend, S. R.; Hicks, J.
10.1101/2024.08.19.608632 — cancer biology — Posted on 2024-08-23
1427 Easy, fast and reproducible Stochastic Cellular Automata with 'chouca'
Genin, A.; Dupont, G.; Valencia, D.; Zucconi, M.; Avila-Thieme, M. I.; Navarrete, S.; Wieters, E.
10.1101/2023.11.08.566206 — ecology — Posted on 2024-08-23
1429 Cell swelling enhances canonical β-adrenergic signaling
Sirbu, A.; Bathe-Peters, M.; Kumar, J. L. M.; Inoue, A.; Lohse, M.; Annibale, P.
10.1101/2023.06.23.544496 — cell biology — Posted on 2024-08-23
1432 Functional capacities drive recruitment of bacteria into plant root microbiota
Selten, G.; Lamouche, F.; Gomez-Repolles, A.; Blahovska, Z.; Kelly, S.; de Jonge, R.; Radutoiu, S.
10.1101/2024.08.22.609090 — plant biology — Posted on 2024-08-23
1433 The p.H222P lamin A/C mutation induces heart failure via impaired mitochondrial calcium uptake in human cardiac laminopathy
Seguret, M.; Jouve, C.; Ruiz-velasco, A.; Deshayes, L.; Guesmia, Z.; Pereira, C.; Wahbi, K.; Fauconnier, J.; Bonne, G.; Muchir, A.; Hulot, J.-S.
10.1101/2024.08.21.609073 — pathology — Posted on 2024-08-23
1434 NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansion
Taghavi, A.; Chen, J. L.; Wang, Z.; Sinnadurai, K.; Salthouse, D.; Ozon, M.; Feri, A.; Fountain, M. A.; Choudhary, S.; Childs-Disney, J. L.; Disney, M. D.
10.1101/2024.08.20.608150 — biophysics — Posted on 2024-08-23
1435 GENA-LM: A Family of Open-Source Foundational DNA Language Models for Long Sequences
Fishman, V.; Kuratov, Y.; Shmelev, A.; Petrov, M.; Penzar, D.; Shepelin, D.; Chekanov, N.; Kardymon, O.; Burtsev, M.
10.1101/2023.06.12.544594 — bioinformatics — Posted on 2024-08-23
1437 PriMAT: A robust multi-animal tracking model for primates in the wild
Vogg, R.; Nuske, M.; Weis, M. A.; Luddecke, T.; Karakoc, E.; Ahmed, Z.; Pereira, S.; Malaivijitnond, S.; Meesawat, S.; Worgotter, F.; Kappeler, P. M.; Gail, A.; Ostner, J.; Schulke, O.; Fichtel, C.; Ecker, A. S.
10.1101/2024.08.21.607881 — animal behavior and cognition — Posted on 2024-08-23
1440 Epigenetic inheritance mediates phenotypic diversity in natural populations
Shahzad, Z.; Moore, J. D.; Choi, J.; Cassin-Ross, G.; Rouached, H.; Zilberman, D.
10.1101/2021.03.15.435374 — evolutionary biology — Posted on 2024-08-23
1441 Molecular profile, source and lineage restriction of stem cells in an annelid regeneration model
Stockinger, A. W.; Adelmann, L.; Fahrenberger, M.; Ruta, C.; Ozpolat, B. D.; Milivojev, N.; Balavoine, G.; Raible, F.
10.1101/2024.07.09.602635 — developmental biology — Posted on 2024-08-23
1442 Platelets as key cells in endometriosis patients: insights from small extracellular vesicles in peritoneal fluid and endometriotic lesions analysis
Bortot, B.; Di Florio, R.; Merighi, S.; Peacock, B.; Lees, R.; Valle, F.; Brucale, M.; Mangogna, A.; Di Lorenzo, G.; Romano, F.; Zito, G.; Zanconati, F.; Ricci, G.; Cancila, V.; Belmonte, B.; Biffi, S.
10.1101/2024.08.21.607595 — cell biology — Posted on 2024-08-23
1444 TRACKING CLONAL AND PLASMID TRANSMISSION IN COLISTIN AND CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE
Akintayo, I.; Siroglavic, M.; Frolova, D.; Silva, M. B.; Grundmann, H.; Iqbal, Z.; Budmir, A.; Reuter, S.
10.1101/2024.08.20.608806 — microbiology — Posted on 2024-08-23
1448 Conservation of molecular responses upon viral infection in the non-vascular plant Marchantia polymorpha
Ros-Moner, E.; Jimenez-Gongora, T.; Villar-Martin, L.; Vogrinec, L.; Gonzalez-Miguel, V. M.; kutnjak, D.; Rubio-Somoza, I.
10.1101/2023.11.06.565823 — plant biology — Posted on 2024-08-23
1450 Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases
Liu, J.; Shah, A.; Ma, Y.; Hardman, K.; Johansson, N. G.; De Castro Ribeiro, O. M.; Brookfield, A.; Bowen, A.; Yli-Kauhaluoma, J.; Xhaard, H.; Jeuken, L.; Goldman, A.; Pliotas, C.; Vidilaseris, K.
10.1101/2024.07.26.605302 — biochemistry — Posted on 2024-08-23
1452 Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health
Aranda-Diaz, A.; Vickers, E. N.; Murie, K.; Palmer, B.; Hathaway, N.; Gerlovina, I.; Boene, S.; Garcia-Ulloa, M.; Cistero, P.; Katairo, T.; Semakuba, F. D.; Nsengimaana, B.; Gwarinda, H.; Garcia-Fernandez, C.; Da Silva, C.; Datta, D.; Kiyaga, S.; Wiringilimaana, I.; Fekele, S. M.; Parr, J. B.; Conrad, M.; Raman, J.; Tukwasibwe, S.; Ssewanyana, I.; Rovira-Vallbona, E.; Tato, C. M.; Briggs, J.; Mayor, A.; Greenhouse, B.
10.1101/2024.08.22.609145 — genomics — Posted on 2024-08-23
1453 Pregranulosa cells upregulate cardiac troponin I Tnni3 upon cell cycle resumption during primordial follicle activation.
Taylor, G.; Frost, E. R.; Crow, B. N.; Radley, A.; Boeing, S.; Galichet, C.; Baker, M. A.; Sutherland, J. M.; Lovell-Badge, R.
10.1101/2022.10.24.513438 — developmental biology — Posted on 2024-08-23
1456 A developmental cell atlas of the human thyroid gland
Massalha, H.; Trinh, M. K.; Armingol, E.; Tuck, L.; Predeus, A.; Mazin, P.; Sancho-Serra, C.; Oszlanczi, A.; Wood, Y.; Parks, C.; Ogbonnah, T.; Whitfield, H. J.; Kelava, I.; Behjati, S.; Vento-Tormo, R.; Schoenmakers, N.
10.1101/2024.08.22.609152 — genomics — Posted on 2024-08-22
1457 Capturing changes to animal complexity from quantifiable patterns in genomic data
Peterson, K. J.; Clarke, A.; Zolotarov, G.; Deline, B.; McPeek, M.; Martinez, P.; Fromm, B.
10.1101/2024.08.22.609214 — evolutionary biology — Posted on 2024-08-22
1459 Genotype dependence of virulence-associated genes in ESBL-producing Escherichia coli isolated from the blood of patients with urinary tract infections
Tanaka, M.; Hanawa, T.; Suda, T.; Tanji, Y.; Le, M. N.; Kondo, K.; Azame, A. H.; Kiga, K.; Yonetani, S.; Yashiro, R.; Omori, T.; Matsuda, T.
10.1101/2024.08.21.608955 — microbiology — Posted on 2024-08-22
1460 The neural mechanisms of fast versus slow decision-making
Nashaat, M.; Oraby, H.; Krasniqi, F.; Goh-Sauerbier, S. T.; Bosc, M.; Koerner, S.; Karayel, S.; Kepecs, A.; Larkum, M.
10.1101/2024.08.22.608577 — neuroscience — Posted on 2024-08-22
1461 Generation of humanized mouse models to support therapeutic development for SYNGAP1 and STXBP1 disorders
Felix, A. J.; Wilson, T.; Randell, R.; Marotta, N.; Uchida, K.; Boland, M. J.; Davidson, B. L.; Prosser, B. L.
10.1101/2024.08.22.609238 — neuroscience — Posted on 2024-08-22
1462 Latent Diffusion For Conditional Generation of Molecules
Kaufman, B.; Williams, E. C.; Pederson, R.; Underkoffler, C.; Panjwani, Z.; Wang-Henderson, M.; Mardirossian, N.; Katcher, M. H.; Strater, Z.; Grandjean, J.-M.; Lee, B.; Parkhill, J.
10.1101/2024.08.22.609169 — bioinformatics — Posted on 2024-08-22
1466 Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease
Tremblay, S. A.; Spreng, R. N.; Wearn, A.; Alasmar, Z.; Pirhadi, A.; Tardif, C. L.; Chakravarty, M.; Villeneuve, S.; Leppert, I. R.; Carbonell, F.; Iturria-Medina, Y.; Steele, C. J.; Gauthier, C. J.; the PREVENT-AD Research Group,
10.1101/2024.08.21.608995 — neuroscience — Posted on 2024-08-22
1467 Speech Synthesis from Electrocorticogram During Imagined Speech Using a Transformer-Based Decoder and Pretrained Vocoder
Komeiji, S.; Shigemi, K.; Mitsuhashi, T.; Iimura, Y.; Suzuki, H.; Sugano, H.; Shinoda, K.; Yatabe, K.; Tanaka, T.
10.1101/2024.08.21.608927 — neuroscience — Posted on 2024-08-22
1468 Confinement and Catalysis Within De Novo Designed Peptide Barrels
Petrenas, R.; Hawkins, O. A.; Jones, J. F.; Scott, D. A.; Fletcher, J. M.; Obst, U.; Lombardi, L.; Pirro, F.; Leggett, G. J.; Oliver, T. A. A.; Woolfson, D. N.
10.1101/2024.08.22.609140 — synthetic biology — Posted on 2024-08-22
1470 Altered host pyruvate metabolism fuels and regulates fungal asexual reproduction
Lee, M. Y.; Jaenisch, J.; McRae, A. G.; Hirai-Adachi, C.; Louie, K.; Silva, L. P.; Bowen, B. P.; Northen, T. R.; Wildermuth, M. C.
10.1101/2024.08.22.609210 — plant biology — Posted on 2024-08-22
1471 Functional capacities drive recruitment of bacteria into plant root microbiota
Selten, G.; Lamouche, F.; Gomez-Repolles, A.; Blahovska, Z.; Kelly, S.; de Jonge, R.; Radutoiu, S.
10.1101/2024.08.22.609090 — plant biology — Posted on 2024-08-22
1474 Visualizing Single V-ATPase Rotation Using Janus Nanoparticles
Otomo, A.; Wiemann, J.; Bhattacharyya, S.; Yamamoto, M.; Yu, Y.; Iino, R.
10.1101/2024.08.22.609254 — biophysics — Posted on 2024-08-22
1476 Structural basis of phosphate export by human XPR1
He, Q.; Zhang, R.; Tury, S.; Courgnaud, V.; Liu, F.; Battini, J.-l.; Li, B.; Chen, Q.
10.1101/2024.08.22.609128 — biochemistry — Posted on 2024-08-22
1477 An NADH-controlled gatekeeper of ATP synthase
Schildhauer, F.; Ryl, P. S.; Lauer, S. M.; Lenz, S.; Barlas, A. B.; Ouzounidis, V. R.; Jeffrey, K.; Marcu, D.-C.; O'Reilly, F. J.; Graziadei, A.; Stuiver, M.; Schmidt, K.; Ewers, H.; Spahn, C. M.; Karaca, E.; Busch, K. E.; Cheerambathur, D.; Schwefel, D.; Rappsilber, J.
10.1101/2024.08.22.609182 — biochemistry — Posted on 2024-08-22
1479 Genomic sequence analysis of the first mpox virus detected in Kenya
Langat, S. K.; Limbaso, K. S.; Khamadi, S. A.; Nyunja, A.; Pilarowski, G.; Okunga, E.; Ofula, V.; Oluniyi, P.; Koka, H.; Koskei, E.; Owaka, S.; Chelangat, B.; Mulwa, F.; Mutisya, J.; Chepkorir, E.; Lutomiah, J.; Langat, D.; Amoth, P.; Songok, E.
10.1101/2024.08.20.608891 — genomics — Posted on 2024-08-22
1480 High-resolution Inference of Multiplexed Anti-HIV Gene Editing using Single-Cell Targeted DNA Sequencing
Bouzidi, M.; Dossani, Z.; Di Benedetto, C.; Raymond, K.; Desai, S.; Chavez, L.; Betancur, P.; Pillai, S. K.
10.1101/2024.01.24.576921 — genomics — Posted on 2024-08-22
1481 Zfp263 is a transcriptional checkpoint of neutrophil development
Devaprasad, A.; Ai, Z.; Mukherjee, A. K.; Panczel, A.; Khoyratty, T.; Ballesteros, I.; Rubio-Ponce, A.; Grinsven, E. v.; Wang, L.; Gomez, J. S.; Eames, H. L.; Hidalgo, A.; Mocsai, A.; Udalova, I. A.
10.1101/2024.08.22.609132 — genomics — Posted on 2024-08-22
1482 Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health
Aranda-Diaz, A.; Vickers, E. N.; Murie, K.; Palmer, B.; Hathaway, N.; Gerlovina, I.; Boene, S.; Garcia-Ulloa, M.; Cistero, P.; Katairo, T.; Semakuba, F. D.; Nsengimaana, B.; Gwarinda, H.; Garcia-Fernandez, C.; Da Silva, C.; Datta, D.; Kiyaga, S.; Wiringilimaana, I.; Fekele, S. M.; Parr, J. B.; Conrad, M.; Raman, J.; Tukwasibwe, S.; Ssewanyana, I.; Rovira-Vallbona, E.; Tato, C. M.; Briggs, J.; Mayor, A.; Greenhouse, B.
10.1101/2024.08.22.609145 — genomics — Posted on 2024-08-22
1483 Genomics-driven monitoring of Fraxinus latifolia (Oregon Ash) for conservation and EAB-resistance breeding
Melton, A. E.; Faske, T. M.; Sniezko, R. A.; Thibault, T.; Williams, W.; Parchman, T.; Hamilton, J. A.
10.1101/2024.08.22.609160 — genomics — Posted on 2024-08-22
1484 Variant-to-function mapping of late-onset Alzheimer's disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus
Burton, E. A.; Argenziano, M.; Cook, K.; Ridler, M.; Lu, S.; Su, C.; Manduchi, E.; Littleton, S. H.; Leonard, M. E.; Hodge, K. M.; Wang, L.-S.; Schellenberg, G. D.; Johnson, M. E.; Pahl, M. C.; Pippin, J. A.; Wells, A. D.; Anderson, S. A.; Brown, C. D.; Grant, S. F.; Chesi, A.
10.1101/2024.08.22.609230 — genetics — Posted on 2024-08-22
1485 Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy
Jeon, E. Y.; Kwak, Y.; Kang, H.; Jin, S. Y.; Park, S.; Kim, R. G.; Ko, D.; Won, J.-K.; Cho, A.; Jung, I.; Lee, C.-H.; Park, J.; Kim, H.-Y.; Chae, J.-H.; Choi, M.
10.1101/2024.08.22.609220 — genetics — Posted on 2024-08-22
1487 Endothelial MICU1 protects against vascular inflammation and atherosclerosis by inhibiting mitochondrial calcium uptake
Sun, L.; Leng, R.; He, Q.; Su, M.; Zhang, Z.; Liu, Z.; Wang, Z.; Jiang, H.; Liu, M.; Wang, L.; Huo, Y.; Miller, C. L.; Banach, M.; Huang, Y.; Evans, P. C.; Pelisek, J.; Camici, G. G.; Berk, B. C.; Offermanns, S.; Ge, J.; Xu, S.; Weng, J.
10.1101/2024.08.22.609192 — molecular biology — Posted on 2024-08-22
1491 Genomic Epidemiology and Microevolution of the Zoonotic Pathogen Corynebacterium ulcerans
Crestani, C.; Passet, V.; Rethoret-Pasty, M.; Criscuolo, A.; Zidane, N.; Bremont, S.; Badell, E.; Brisse, S.
10.1101/2024.08.22.609154 — microbiology — Posted on 2024-08-22
1493 Orally surface engineered probiotic system for ulcerative colitis therapy via modulating gut microbiota and immune homeostasis
Liu, J.; Fang, Z.; Zhang, X.; Chen, Y.; Kou, F.; Li, X.; Huang, L.; Yang, H.; Zheng, Y.; Huang, Y.; Wang, Y.; Qiu, X.; Ge, J.; Qian, Y.; Xing, X.-H.; Zhang, C. Y.
10.1101/2024.08.22.609086 — microbiology — Posted on 2024-08-22
1496 Astrocyte extracellular matrix modulates neuronal dendritic development
Hashimoto, J. G.; Margolies, N.; Zhang, X.; Karpf, J.; Song, Y.; Davis, B. A.; Zhang, F.; Linhardt, R. J.; Carbone, L.; Guizzetti, M.
10.1101/2024.08.06.606424 — neuroscience — Posted on 2024-08-22
1498 δ-α cell-to-cell interactions modulate pancreatic islet Ca2+ oscillation modes
Ren, H.; Li, Y.; Xie, B.; Qian, W.; Yu, Y.; Chang, T.; Yang, X.; sneppen, k.; Chen, L.; Tang, C.
10.1101/2024.08.21.608986 — systems biology — Posted on 2024-08-22
1500 FUSION: A web-based application for in-depth exploration of multi-omics data with brightfield histology
Border, S.; Melo Ferreira, R.; Lucarelli, N.; Manthey, D.; Kumar, S.; Paul, A.; Mimar, S.; Naglah, A.; Cheng, Y.-H.; Barisoni, L.; Ray, J.; Strekalova, Y.; Rosenberg, A. Z.; Tomaszewski, J. E.; Hodgin, J. B.; HuBMAP consortium, ; El-Achkar, T. M.; Jain, S.; Eadon, M. T.; Sarder, P.
10.1101/2024.07.09.602778 — pathology — Posted on 2024-08-22
1502 Cross-species modeling of plant genomes at single nucleotide resolution using a pre-trained DNA language model
Zhai, J.; Gokaslan, A.; Schiff, Y.; Berthel, A.; Liu, Z.-Y.; Lai, W.-Y.; Miller, Z. R.; Scheben, A.; Stitzer, M. C.; Romay, C.; Buckler, E. S.; Kuleshov, V.
10.1101/2024.06.04.596709 — bioinformatics — Posted on 2024-08-22
1504 Spatiotemporally-resolved mapping of extracellular proteomes via in vivo-compatible TyroID
Zhang, Z.; Wang, Y.; Lu, W.; Wang, X.; Guo, H.; Pan, X.; Liu, Z.; Wu, Z.; Qin, W.
10.1101/2024.08.22.609124 — biochemistry — Posted on 2024-08-22
1505 Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency
Naqvi, A. S.; Corbett, R. J.; Seghal, P.; Conkrite, K. L.; Rathi, K. S.; Ennis, B. M.; Hayer, K. E.; Zhang, B.; Brown, M. A.; Miller, D. P.; Kraya, A.; Dybas, J. M.; Geng, Z.; Blackden, C.; Arif, S.; Chroni, A.; Lahiri, A.; Hollawell, M. L.; Storm, P. B.; Foster, J. B.; Koptyra, M.; Madsen, P. J.; Diskin, S. J.; Thomas-Tikhonenko, A.; Resnick, A. C.; Rokita, J. L.
10.1101/2024.08.03.606419 — genomics — Posted on 2024-08-22
1507 Performance of qpAdm-based screens for genetic admixture on admixture-graph-shaped histories and stepping-stone landscapes
Flegontova, O.; Isıldak, U.; Yüncü, E.; Williams, M. P.; Huber, C. D.; Koci, J.; Vyazov, L. A.; Changmai, P.; Flegontov, P.
10.1101/2023.04.25.538339 — genetics — Posted on 2024-08-22
1508 Temporally resolved single cell transcriptomics in a human model of amniogenesis
Sekulovski, N.; Carleton, A. E.; Rengarajan, A. A.; Lin, C.-W.; Juga, L. L.; Whorton, A. E.; Kropp Schmidt, J.; Golos, T.; Taniguchi, K.
10.1101/2023.09.07.556553 — developmental biology — Posted on 2024-08-22
1509 Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features
Shayler, D. W. H.; Stachelek, K.; Cambier, L.; Lee, S.; Bai, J.; Reid, M. W.; Weisenberger, D. J.; Bhat, B.; Aparicio, J. G.; Kim, Y.; Singh, M.; Bay, M.; Thornton, M. E.; Doyle, E. K.; Fouladian, Z.; Erberich, S. G.; Grubbs, B. H.; Bonaguidi, M. A.; Craft, C. M.; Singh, H. P.; Cobrinik, D.
10.1101/2023.02.28.530247 — developmental biology — Posted on 2024-08-22
1510 Intracellular Ebola Virus nucleocapsid assembly revealed by in situ cryo-electron tomography.
Watanabe, R.; Zyla, D.; Parekh, D.; Hong, C.; Jones, Y.; Schendel, S. L.; Wan, W.; Castillon, G.; Saphire, E. O.
10.1101/2023.12.01.569666 — microbiology — Posted on 2024-08-22
1513 Spatial Coherence in DNA Barcode Networks
Bonet, D. F.; Blumenthal, J. I.; Lang, S.; Dahlberg, S. K.; Hoffecker, I. T.
10.1101/2024.05.12.593725 — bioinformatics — Posted on 2024-08-22
1514 Multimodal Protein-Ligand Contrastive Pretraining for Effective and Efficient Drug Discovery
Wang, Z.; Wang, Z.; Yang, M.; Pang, L.; Nie, F.; Liu, S.; Gao, Z.; Zhao, G.; Ji, X.; Huang, D.; Zhu, Z.; Li, D.; Yuan, Y.; Zheng, H.; Zhang, L.; Ke, G.; Wang, D.; Yu, F.
10.1101/2024.08.22.609123 — bioinformatics — Posted on 2024-08-22
1515 Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging
Din, M.; Paul, S.; Ullah, S.; Yang, H.; Xu, R.-G.; Abidin, N. A. Z.; Sun, A.; Chen, Y. C.; Gao, R.; Chowdhury, B.; Zhou, F.; Rogers, S.; Miller, M.; Biswas, A.; Hu, L.; Fan, Z.; Zahner, C.; Fan, J.; Chen, Z.; Berman, M.; Xue, L.; Ju, L. A.; Chen, Y.
10.1101/2024.06.11.598290 — bioengineering — Posted on 2024-08-22
1516 Stimulative piezoelectric nanofibrous scaffolds for enhanced small extracellular vesicle production in 3D cultures
Johnston, J.; Jeon, H.; Choi, Y. Y.; Kim, G.; Shi, T.; Khong, C.; Chang, H.-C.; Myung, N. V.; Wang, Y.
10.1101/2024.04.12.589114 — bioengineering — Posted on 2024-08-22
1518 NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT
Shukla, V.; Irusta, A. M.; Varberg, K. M.; Kuna, M.; Iqbal, K.; Galligos, A. M.; Aplin, J. D.; Choudhury, R. H.; Okae, H.; Arima, T.; Soares, M. J.
10.1101/2024.02.13.579974 — developmental biology — Posted on 2024-08-22
1520 Immunological landscape of human lymphoid explants during measles virus infection
Acklin, J. A.; Patel, A. R.; Kurland, A. P.; Horiuchi, S.; Moss, A. S.; Degrace, E. J.; Ikegame, S.; Carmichael, J.; Kowdle, S.; Thibault, P.; Imai, N.; Ueno, H.; Tweel, B.; Johnson, J. R.; Rosenberg, B. R.; Lee, B.; Lim, J. K.
10.1101/2022.09.12.507535 — immunology — Posted on 2024-08-22
1521 Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis
Gutierrez-Jimenez, E.; Rasmussen, P. M.; Mikkelsen, I. K.; Kura, S.; Fruekilde, S. K.; Hansen, B.; Bordoni, L.; Carlsen, J.; Palmfeldt, J.; Boas, D. A.; Sakadzic, S.; Vinogradov, S. A.; El Khatib, M.; Ramos-Cejudo, J.; Wied, B.; Leduc-Galindo, D.; Canepa, E.; Mar, A. C.; Gamallo-Lana, B.; Fossati, S.; Ostergaard, L.
10.1101/2024.08.22.609091 — neuroscience — Posted on 2024-08-22
1523 DNA co-methylation has a stable structure and is related to specific aspects of genome regulation
Watkins, S. H.; Suderman, M.; Hemani, G.; Burrows, K.; Lawlor, D. A.; West, J.; Willan, K.; Timpson, N. J.; Min, J.; Gaunt, T. R.
10.1101/2022.03.16.484648 — bioinformatics — Posted on 2024-08-22
1524 Cathepsin B causes trogocytosis-mediated CAR T cell dysfunction
Dietze, K. A.; Nguyen, K.; Pathni, A.; Fazekas, F.; Baker, J. M.; Gebru, E.; Wang, A.; Sun, W.; Rosati, E.; Lum, D.; Rapoport, A. P.; Fan, X.; Atanackovic, D.; Upadhyaya, A.; Luetkens, T.
10.1101/2024.06.11.598379 — bioengineering — Posted on 2024-08-22
1526 The CALERIE™ Genomic Data Resource
Ryan, C. P.; Corcoran, D. L.; Banskota, N.; Eckstein Indik, C.; Floratos, A.; Friedman, R. A.; Kobor, M. S.; Kraus, V. B.; Kraus, W.; MacIsaac, J. L.; Orenduff, M. C.; Pieper, C. F.; White, J. P.; Ferrucci, L.; Horvath, S.; Huffman, K. M.; Belsky, D. W.
10.1101/2024.05.17.594714 — genomics — Posted on 2024-08-22
1528 Benchmarking automated detection and classification approaches for monitoring of endangered species: a case study on gibbons from Cambodia
Clink, D. J.; Cross-Jaya, H.; Kim, J.; Ahmad, A. H.; Hong, M.; Sala, R.; Birot, H.; Agger, C.; Vu, T. T.; Thi, H. N.; Chi, T. N.; Klinck, H.
10.1101/2024.08.17.608420 — ecology — Posted on 2024-08-22
1531 Disentangling signal and noise in neural responses through generative modeling
Kay, K.; Prince, J. S.; Gebhart, T.; Tuckute, G.; Zhou, J.; Naselaris, T.; Schutt, H.
10.1101/2024.04.22.590510 — neuroscience — Posted on 2024-08-22
1533 Counting on AR: EEG responses to incongruent information with real-world context
Wimmer, M.; Pepicelli, A.; Volmer, B.; ElSayed, N.; Cunningham, A.; Thomas, B. H.; Müller-Putz, G. R.; Veas, E. E.
10.1101/2024.08.22.608951 — neuroscience — Posted on 2024-08-22
1534 A new genome-scale metabolic model of oleaginous microalgae with refined lipid metabolism elucidates Microchloropsis gaditana mutant phenotypes.
Dupont-Thibert, C.; Roy, S.; Carneiro, S.; Pereira, B.; Careira, R.; Vilaca, P.; Collin, S.; Marechal, E.; Billey, E.; Curien, G.; Durot, M.; Jouhet, J.
10.1101/2023.12.06.570374 — plant biology — Posted on 2024-08-22
1535 A deep-learning based analysis framework for ultra-high throughput screening time-series data
Balzerowski, P.; Gnutt, D.; Hebing, L.; Lima, F. d. A. e.; Manesso, E.; Mueller, T.; Diedam, H.
10.1101/2024.08.22.609110 — bioinformatics — Posted on 2024-08-22
1536 Machine learning model to predict risk assessment of a child inheriting a genetic disorder
Ramaswamy, M.; Senthilnathan, S.; Saravanan, A. R. I.; M, S.; Sivashanmugam, K.
10.1101/2024.08.22.609095 — genetics — Posted on 2024-08-22
1539 Development of Pial Collaterals by Extension of Pre-existing Artery Tips
Kumar, S.; Ghosh, S.; Shanavas, N.; Sivaramakrishnan, V.; Dwari, M.; Das, S.
10.1101/2023.12.07.570539 — developmental biology — Posted on 2024-08-22
1541 Conservation of gene expression patterns between the amniotic epithelium at birth and a newborn's nasal epithelium
Hancock, D. G.; Agudelo-Romero, P.; Kicic-Starcevich, E.; Lim, J.; Iosifidis, T.; Karpievitch, Y. V.; Zhang, G.; Martino, D. J.; Kicic, A.; Stick, S. M.
10.1101/2024.08.22.609087 — molecular biology — Posted on 2024-08-22
1542 DNA damage response defects induced by the formation of TDP-43 and mutant FUS cytoplasmic inclusions and their pharmacological rescue.
Farina, S.; Esposito, F.; Modafferi, S.; Brandi, O.; Di Salvio, M.; Della Valle, I.; Cicio, G.; Riccardi, A.; Pisati, F.; Garbelli, A.; D'ambrosi, N.; Cozzolino, M.; Cestra, G.; d'Adda di Fagagna, F.; Gioia, U.; Francia, S.
10.1101/2024.08.22.609115 — molecular biology — Posted on 2024-08-22
1548 Activation and Evasion of the FEAR Pathway by RNA Viruses
Rex, E. A.; Seo, D.; Embry, A.; Arulanandam, R.; Spinelli, M. M.; Diallo, J.-S.; Gammon, D. B.
10.1101/2024.08.22.609092 — microbiology — Posted on 2024-08-22
1550 chrna3 modulates biphasic response to alcohol
Raine, J.; Kibat, C.; Banerjee, T. D.; Monteiro, A.; Mathuru, A.
10.1101/2024.08.22.607435 — neuroscience — Posted on 2024-08-22
1554 Terminal nucleotidyltransferase Tent2 microRNA tailing regulates excitatory/inhibitory balance in the hippocampus
Wardaszka, P.; Kuzniewska, B.; Guminska, N.; Hojka-Osinska, A.; Puchalska, M.; Milek, J.; Stawikowska, A.; Krawczyk, P.; Pauzin, F. P.; Wojtowicz, T.; Radwanska, K.; Bramham, C. R.; Dziembowski, A.; Dziembowska, M.
10.1101/2024.08.22.609125 — neuroscience — Posted on 2024-08-22
1556 Single neurons and networks in the claustrum integrate input from widespread cortical sources
Shelton, A. M.; Oliver, D. K.; Lazarte, I. P.; Grimstvedt, J. S.; Kapoor, I.; Swann, J. A.; Ashcroft, C. A.; Williams, S. N.; Conway, N.; Tir, S.; Robinson, A.; Peirson, S. N.; Akam, T.; Kentros, C.; Witter, M. P.; Butt, S. J.; Packer, A. M.
10.1101/2022.05.06.490864 — neuroscience — Posted on 2024-08-22
1557 Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma
Mariniello, K.; Pittaway, J. F. H.; Altieri, B.; Silva Borges, K.; Hadjidemetriou, I.; Ribeiro, C.; Ruiz-Babot, G.; Lim, J. A.; Foster, J.; Cleaver, J.; Sosabowski, J.; Rahman, N.; Doroszko, M.; Hantel, C.; Sigala, S.; Abate, A.; Tamburello, M.; Kiseljak-Vassiliades, K.; Wierman, M.; Parvanta, L.; Abdel-Aziz, T. E.; Chung, T.-T.; DiMarco, A.; Palazzo, F.; Gomez-Sanchez, C. E.; Taylor, D.; Rayner, O.; Ronchi, C. L.; Gaston-Massuet, C.; Sbiera, S.; Drake, W. M.; Rognoni, E.; Kroiss, M.; Breault, D. T.; Fassnacht, M.; Guasti, L.
10.1101/2024.08.22.609117 — cancer biology — Posted on 2024-08-22
1560 Telomere-to-telomere, gap-free genome of mung beans (Vigna radiata) provides insights into domestication under structural variation
Jia, K.-H.; Li, G.; Wang, L.; Liu, M.; Wang, Z.-W.; Li, R.-Z.; Li, L.-L.; Xie, K.; Yang, Y.-Y.; Tian, R.-M.; Chen, X.; Si, Y.-J.; Zhang, X.-Y.; Song, F.-J.; Li, N.-N.
10.1101/2024.08.21.609077 — genomics — Posted on 2024-08-22
1564 Post-translational modifications on protein VII are important during the early stages of adenovirus infection.
Arnold, E. A.; Smith, J. R.; Leung, K.; Nguyen, D. H.; Kelnhofer-Millevolte, L. E.; Guo, M. S.; Smith, J. G.; Avgousti, D. C.
10.1101/2024.08.21.609089 — microbiology — Posted on 2024-08-22
1565 Unveiling the potato cultivars with microbiome interactive traits for sustainable agricultural production
Zhao, T.; Vink, S. N.; Jia, X.; Erban, A.; Schaarschmidt, S.; Kopka, J.; Zuther, E.; Treder, K.; Michalowska, D.; Attard, E.; Guyoneaud, R.; Elzenga, J. T. M.; Falcao Salles, J.
10.1101/2024.08.21.609084 — microbiology — Posted on 2024-08-22
1566 WHIX is a T6SS secretion domain found in polymorphic double-edged sword effectors
Fridman, C. M.; Keppel, K.; Rudenko, V.; Altuna-Alvarez, J.; Albesa-Jove, D.; Bosis, E.; Salomon, D.
10.1101/2024.08.21.608442 — microbiology — Posted on 2024-08-22
1568 Vagal TRPV1+ sensory neurons regulate myeloid cell dynamics and protect against influenza virus infection
Yang, D.; Almanzar, N.; Xia, J.; Udit, S.; Yeung, S. T.; Khairallah, C.; Hoagland, D. A.; Umans, B. D.; Sarden, N.; Erdogan, O.; Baalbaki, N.; Beekmayer-Dhillon, A.; Lee, J.; Meerschaert, K. A.; Liberles, S. D.; Yipp, B. G.; Franklin, R. A.; Khanna, K. M.; Baral, P.; Haber, A. L.; Chiu, I. M.
10.1101/2024.08.21.609013 — immunology — Posted on 2024-08-22
1569 MLL1 directs gut-associated antibody responses to helminth and bacterial infections
Zhang, Y.; Chakma, C.; Kirn, A.; Zaini, A.; Farighi, R.; Xie, L.; Lopez-Urena, D.; Mileto, S.; Lyras, D.; Zaph, C.; Groom, J. R.; Good-Jacobson, K.
10.1101/2024.08.21.609083 — immunology — Posted on 2024-08-22
1574 To integrate or not to integrate: Testing degenerate strategies for solving an accumulation of perceptual evidence decision-making task
Kopec, C. D.; Luo, T. Z.; Bondy, A. G.; Gupta, D.; Elliott, V. A.; Charlton, J. A.; Breda, J. R.; Stagnaro, W. M.; Reyes, E. J.; Sirko, A. I.; Bustos, A. F.; Willock, J. M.; Morrison, J. M.; Osorio, K. L.; Brody, C. D.
10.1101/2024.08.21.609064 — animal behavior and cognition — Posted on 2024-08-22
1578 Distinct functions of PAXX and MRI during chromosomal end joining
Cisneros-Aguirre, M.; Lopezcolorado, F. W.; Ping, X.; Chen, R.; Stark, J. M.
10.1101/2024.08.21.607864 — genetics — Posted on 2024-08-22
1582 Epigenetic and transcriptional regulation of ovarian development altered in ErβKO ovaries
Mohamadi, R.; Vo, K.; Sharma, Y.; Mohamadi, A.; Bahadursingh, E.; Fields, P. E.; Rumi, M. A.
10.1101/2024.08.21.608994 — developmental biology — Posted on 2024-08-22
1584 Spatiotemporal Analysis of Lung Immune Dynamics in Lethal Coccidioides posadasii Infection
Davalos, O. A.; Sebastian, A.; Leon, N. F.; Rangel, M. V.; Miranda, N.; Murugesh, D. K.; Phillips, A. M.; Hoyer, K. K.; Hum, N. R.; Loots, G. G.; Weilhammer, D.
10.1101/2024.08.21.609002 — immunology — Posted on 2024-08-22
1585 Early immune response to Coccidioides is characterized by robust neutrophil and fibrotic macrophage recruitment and differentiation
Miranda, N.; Davalos, O. A.; Sebastian, A.; Rangel, M. V.; Leon, N. F.; Gorman, B. M.; Murugesh, D. K.; Hum, N. R.; Loots, G. G.; Hoyer, K. K.; Weilhammer, D.
10.1101/2024.08.21.609001 — immunology — Posted on 2024-08-22
1587 A first-in-kind MAPK13 inhibitor that can correct stem cell reprogramming and post-injury disease
Zhang, Y.; Wu, K.; Mao, D.; Iberg, C. A.; Yin-Declue, H.; Sun, K.; Wikfors, H. A.; Keeler, S. P.; Li, M.; Young, D.; Yantis, J.; Crouch, E. C.; Chartock, J. R.; Han, Z.; Byers, D. E.; Brody, S. L.; Romero, A. G.; Holtzman, M. J.
10.1101/2024.08.21.608990 — immunology — Posted on 2024-08-22
1588 Keratinocyte-derived exosomes in painful diabetic neuropathy
Coy-Dibley, J.; Jayaraj, N. D.; Ren, D.; Pacifico, P.; Belmadni, A. A.; Wang, Y.-Z.; Gebis, K. K.; Savas, J. N.; Paller, A. S.; Miller, R. J.; Menichella, D. M.
10.1101/2024.08.21.608803 — neuroscience — Posted on 2024-08-22
1590 Coordinated cross-brain activity during accumulation of sensory evidence and decision commitment
Bondy, A. G.; Charlton, J. A.; Luo, T. Z.; Kopec, C. D.; Stagnaro, W. M.; Venditto, S. J. C.; Lynch, L.; Janarthanan, S.; Oline, S. N.; Harris, T. D.; Brody, C. D.
10.1101/2024.08.21.609044 — neuroscience — Posted on 2024-08-22
1592 ActSort: An active-learning accelerated cell sorting algorithm for large-scale calcium imaging datasets
Jiang, Y.; Akengin, H. O.; Zhou, J.; Aslihak, M. A.; Li, Y.; Hernandez, O.; Ebrahimi, S.; Zhang, Y.; Inan, H.; Jaidar, O.; Miranda, C.; Dinc, F.; Blanco-Pozo, M.; Schnitzer, M. J.
10.1101/2024.08.21.609011 — neuroscience — Posted on 2024-08-22
1595 Changing air density affects flight costs in low-flying birds
Shepard, E. L. C.; Garde, B.; Krishnan, K.; Fell, A.; Tataya, V.; Jones, C. G.; Cole, N. C.; Lempidakis, E.
10.1101/2024.08.21.608961 — zoology — Posted on 2024-08-22
1596 δ-α cell-to-cell interactions modulate pancreatic islet Ca2+ oscillation modes
Tang, C.; Ren, H.; Li, Y.; Xie, B.; Qian, W.; Yu, Y.; Chang, T.; Yang, X.; sneppen, k.; Chen, L.
10.1101/2024.08.21.608986 — systems biology — Posted on 2024-08-22
1598 Divergent Immediate and Delayed Effects of Juvenile Exposure to Doxorubicin on the Thymus in C57BL/6 Mice
George, B.; Dahlquist, K. J. V.; Grant, M. K. O.; Daniel, M. R.; Smith, D. M.; Sadak, K. T.; Seelig, D.; Camell, C. D.; Zordoky, B. N.
10.1101/2024.08.21.609003 — pharmacology and toxicology — Posted on 2024-08-22
1603 Enhanced Maturity and Functionality of Vascularized Human Liver Organoids through 3D Bioprinting and Pillar Plate Culture
Lekkala, V. K. R.; Shrestha, S.; Al Qaryoute, A.; Dhinoja, S.; Acharya, P.; Raheem, A.; Jagadeeswaran, P.; Lee, M.-Y.
10.1101/2024.08.21.608997 — bioengineering — Posted on 2024-08-22
1605 Genomic Characterization of a Dog-Mediated Rabies Outbreak in El Pedregal, Arequipa, Peru
Salazar, R.; Brunker, K.; Diaz, E. W.; Zegarra, E.; Monroy, Y.; Baldarrago, G. N.; Borrini-Mayori, K.; De la Puente-Leon, M.; Kasaragod, S.; Levy, M. Z.; Hampson, K.; Castillo-Neyra, R.
10.1101/2024.08.21.608982 — genomics — Posted on 2024-08-22
1607 Multi-scale dynamics influence the division potential of stomatal lineage ground cells in Arabidopsis
Fung, H. F.; Amador, G. O.; Dale, R.; Gong, Y.; Vollbrecht, M.; Erberich, J. M.; Mair, A.; Bergmann, D. C.
10.1101/2024.08.21.609020 — developmental biology — Posted on 2024-08-22
1610 Olfactory receptor coexpression and co-option in the dengue mosquito
Adavi, E. D.; dos Anjos, V. L.; Kotb, S.; Metz, H. C.; Tian, D.; Zhao, Z.; Zung, J. L.; Rose, N. H.; McBride, C. S.
10.1101/2024.08.21.608847 — neuroscience — Posted on 2024-08-22
1611 A molecular brain atlas reveals cellular shifts during the repair phase of stroke
Weber, R. Z.; Achon Buil, B.; Rentsch, N. H.; Bosworth, A.; Zhang, M.; Kisler, K.; Tackenberg, C.; Zlokovic, B. V.; Rust, R.
10.1101/2024.08.21.608971 — neuroscience — Posted on 2024-08-22
1613 Investigating the impact of the interstitial fluid flow and hypoxia interface on cancer biology using a spheroid-on-chip perfusion system
Pyne, E.; Reardon, M.; Christensen, M.; Rodriguez-Mateos, P.; Taylor, S.; Iles, A.; Choudhury, A.; Pamme, N. M.; Pires, I. M.
10.1101/2024.08.21.608919 — cancer biology — Posted on 2024-08-22
1619 Ex vivo Model of Functioning Human Lymph Node Reveals Pivotal Role for Innate Lymphoid Cells and Stromal Populations in Response to Vaccine Adjuvant
Fergusson, J.; Siu, J.; Gupta, N.; Nee, E.; Reinke, S.; Stroebel, T.; Bhalla, A.; Kandage, S.; Courant, T.; Hill, S.; Attar, M.; Gordon-Weeks, A.; Coles, M.; Dendrou, C.; Milicic, A.
10.1101/2024.08.21.608943 — immunology — Posted on 2024-08-22
1621 Cortical Excitability is Affected by Light Exposure- Distinct Effects in Adolescents and Young Adults
Sharifpour, R.; Balda Aizpurua, F.; Paparella, I.; Read, J.; Leysens, Z.; Letot, S.; Campbell, I.; Beckers, E.; Collette, F.; Phillips, C.; Zubkov, M.; Vandewalle, G.
10.1101/2024.08.21.608922 — neuroscience — Posted on 2024-08-22
1624 A fluorophore-ligand conjugate for the rapid and reversible staining of native AMPA receptors in living neurons
Soga, K.; Fujiwara, T.; Nakagawa, M.; Shibata, A.; Adriel, H.; Yatsuzuka, K.; Kakegawa, W.; Yuzaki, M.; Hamachi, I.; Nango, E.; Kiyonaka, S.
10.1101/2024.08.21.608930 — neuroscience — Posted on 2024-08-22
1626 LEAF SHAPE OF QUINOA WILD ANCESTOR CHENOPODIUM HIRCINUM IN A GEOGRAPHIC CONTEXT
Curti, R. N.; Rodriguez, J.; Ortega-Baes, P.; Bramardi, S. J.; Jellen, E.; Jarvis, D. E.; Maughan, P. J.; Tester, M.; Bertero, D.
10.1101/2024.08.21.608958 — plant biology — Posted on 2024-08-22
1628 Discovery of Novel R-Selective Aminotransferase Motifs through Computational Screening
Runthala, A.; Satya Sri, P. S.; Nair, A. S.; Puttagunta, M. K.; Sekhar Rao, T. C.; Sreya, V.; Sowmya, G. R.; Reddy G, K.
10.1101/2024.08.21.608959 — bioinformatics — Posted on 2024-08-22
1633 Common to rare transfer learning (CORAL) enables inference and prediction for a quarter million rare Malagasy arthropods
Ovaskainen, O.; Winter, S.; Tikhonov, G.; Abrego, N.; Anslan, S.; deWaard, J. R.; deWaard, S. L.; Fisher, B. L.; Furneaux, B.; Hardwick, B.; Kerdraon, D.; Pentinsaari, M.; Raharinjanahary, D.; Rajoelison, E. T.; Ratnasingham, S.; Somervuo, P.; Sones, J. E.; Zakharov, E. V.; Hebert, P. D. N.; Roslin, T.; Dunson, D.
10.1101/2024.08.21.608960 — ecology — Posted on 2024-08-22
1634 The transcription factor BATF pioneers the differentiation program of cytolytic effector CD8+ T cells through the direct interaction with IRF4
Fujisawa, S.; Tanabe, Y.; Hojo, A.; Shiga, R.; Kurachi, J.; Koura, M.; Tamai, T.; Miyanari, Y.; Wherry, E. J.; Kurachi, M.
10.1101/2024.08.21.605975 — immunology — Posted on 2024-08-22
1636 Ecological factors that drive microbial communities in culturally diverse fermented foods
Gautam, A.; Poopalarajah, R.; Ahmad, A. R.; Rana, B.; Denekew, T. W.; Anh, N.; Utenova, L.; Kunwar, Y. S.; Bhandari, N. N.; Jha, A. R.
10.1101/2024.08.20.608727 — microbiology — Posted on 2024-08-22
1637 Cell-free screening, production and animal testing of a STI-related chlamydial major outer membrane protein supported in nanolipoproteins.
Mohagheghi, M. V.; Abisoye-Ogunniyan, A.; Evans, A. C.; Peterson, A. E.; Bude, G. A.; Hoang-Phou, S.; Hall, D.; Rasley, A.; Fischer, N. O.; He, W.; Robinson, B. V.; Pal, S.; Slepenkin, A.; de la Maza, L. M.; Coleman, M. A.
10.1101/2024.08.20.608363 — immunology — Posted on 2024-08-22
1638 Evoked resonant neural activity outperforms spectral markers in decoding sleep from the subthalamic nucleus
Wiest, C.; Simpson, T. G.; Pogosyan, A.; Hasegawa, H.; He, S.; Plazas, F. R.; Wehmeyer, L.; Yassine, S.; Guo, X.; Shah, R.; Merla, A.; Perera, A.; Raslan, A.; O'Keeffe, A.; Hart, M.; Morgante, F.; Pereira, E.; Askan, K.; Tan, H.
10.1101/2024.08.20.608562 — neuroscience — Posted on 2024-08-22
1644 MagnoliidsGDB：An integrated functional genomics database for Magnoliids
Chen, Y.; Yang, Z.; Chen, J.; Li, P.; Zhao, X.; Huang, S.; Li, Z.; Huang, S.; Luo, J.; Hu, H.; Ding, Y.
10.1101/2024.08.19.608005 — evolutionary biology — Posted on 2024-08-22
1646 The long-range gene regulatory landscape of cerebellar granule neuron progenitors
Riegman, K. L. H.; George, C.; Whittaker, D. E.; Ahmed, M. U.; Yun, H.; Huntly, B.; Sims, D.; Osborne, C. S.; Basson, M. A.
10.1101/2024.08.22.609103 — neuroscience — Posted on 2024-08-22
1647 An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality
Whitman, E. T.; Elliott, M. L.; Knodt, A. R.; Abraham, W. C.; Anderson, T. J.; Cutfield, N.; Hogan, S.; Ireland, D.; Melzer, T. R.; Ramrakha, S.; Sugden, K.; Theodore, R.; Williams, B. S.; Caspi, A.; Moffitt, T. E.; Hariri, A. R.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2024.08.19.608305 — neuroscience — Posted on 2024-08-22
1650 Confounding Fuels Misinterpretation in Human Genetics
Benning, J. W.; Carlson, J.; Smith, O.; Shaw, R.; Harpak, A.
10.1101/2023.11.01.565061 — genetics — Posted on 2024-08-22
1651 Recurrent sex chromosome turn-over in termites
Fraser, R.; Moraa, R.; Djolai, A.; Meisenheimer, N.; Laube, S.; Vicoso, B.; Huylmans, A. K.
10.1101/2024.08.12.607539 — evolutionary biology — Posted on 2024-08-22
1653 Chromatin enhancer activity of IκBα mediates the exit from naïve pluripotency
Palma, L. G.; Alvarez-Villanueva, D.; Maqueda, M.; Barrero, M.; IGLESIAS, A.; Bertran, j.; ALVAREZ, D.; GARCIA-PRIETO, C.; BALLARE, C.; RODRIGUEZ-CORTEZ, V.; BUENO, C.; VIDAL, A.; Villanueva, A.; Menendez, P.; Stik, G.; Di Croce, L.; Payer, B.; Esteller, M.; Espinosa, L.; Bigas, A.
10.1101/2023.07.28.550934 — cell biology — Posted on 2024-08-22
1654 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.
10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-08-22
1657 A molecularly distinct cell type in the midbrain regulates intermale aggression behaviors in mice
Li, C.-Y.; Miao, C.; Ge, Y.; Wu, J.; Gao, P.; Yin, S.; Zhang, P.; Yang, H.; Tian, B.; Chen, W.; Chen, X.-Q.
10.1101/2023.10.19.562724 — neuroscience — Posted on 2024-08-22
1659 Real-time Plasmid Transmission Detection Pipeline
Scherff, N.; Rothgänger, J.; Weniger, T.; Mellmann, A.; Harmsen, D.
10.1101/2024.07.09.602722 — bioinformatics — Posted on 2024-08-22
1660 Tagging Methods for Very Small Fish
Bradley, D. D.; Schimke, E. J.; Alvey, A. P.; Hofmann, H. A.; Solomon-Lane, T. K.
10.1101/437772 — animal behavior and cognition — Posted on 2024-08-22
1661 Deciphering the variation in cuticular hydrocarbon profiles of six European honey bee subspecies
Rodriguez-Leon, D. S.; Uzunov, A.; Costa, C.; Dylan, E. S.; Charistos, L.; Galea, T.; Gabel, M.; Scheiner, R.; Pinto, M. A.; Schmitt, T.
10.1101/2024.07.05.601031 — evolutionary biology — Posted on 2024-08-22
1662 First evidence for the evolution of host manipulation by tumors during the long-term vertical transmission of tumor cells in Hydra oligactis
BOUTRY, J.; Oceane, R.; Lena, G.; Jordan, M.; Aurora, N.; Sophie, T.; Beata, U.; Rodrigo, H.; Antoine, D. M.; Jacint, T.; Frederic, T.
10.1101/2024.02.08.579507 — evolutionary biology — Posted on 2024-08-22
1664 Unified Mass Imaging Maps the Lipidome of Vertebrate Development
Schede, H. H.; Haj Abdullah Alieh, L.; Rohde, L.; Hererra, A.; Schlaeppi, A.; Valentin, G.; Motlagh, A. G.; Dominguez Mantes, A. H.; Jollivet, C.; Paz Montoya, J.; Capolupo, L.; Khven, I.; Oates, A. C.; D'Angelo, G.; La Manno, G.
10.1101/2024.08.20.608739 — systems biology — Posted on 2024-08-22
1669 Platelet as key cells in endometriosis patients: insights from small extracellular vesicles in peritoneal fluid and endometriotic lesions analysis
Bortot, B.; Di Florio, R.; Merighi, S.; Peacock, B.; Lees, R.; Valle, F.; Brucale, M.; Mangogna, A.; Di Lorenzo, G.; Romano, F.; Zito, G.; Zanconati, F.; Ricci, G.; Cancila, V.; Belmonte, B.; Biffi, S.
10.1101/2024.08.21.607595 — cell biology — Posted on 2024-08-22
1671 Genetically encoded fluorescent sensors for visualizing polyamine levels, uptake, and distribution
Tamura, R.; Chen, J.; De Jaeger, M.; Morris, J. F.; Scott, D. A.; Vangheluwe, P.; Looger, L. L.
10.1101/2024.08.21.609037 — cell biology — Posted on 2024-08-22
1672 N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine
Wang, C.; Zhao, C.; Hu, X.; Qiang, J.; Liu, Z.; Gu, J.; Zhang, S.; Li, D.; Zhang, Y.; Burre, J.; Diao, J.; Liu, C.
10.1101/2024.03.04.583437 — biophysics — Posted on 2024-08-21
1675 Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex
Johansen, N. J.; Kempynck, N.; Zemke, N. R.; Somasundaram, S.; Winter, S. D.; Hooper, M.; Dwivedi, D.; Lohia, R.; Wehbe, F.; Li, B.; Abaffyova, D.; Armand, E. J.; Man, J. D.; Eksi, E. C.; Hecker, N.; Hulselmans, G.; Konstantakos, V.; Mauduit, D.; Mich, J. K.; Partel, G.; Daigle, T. L.; Levi, B. P.; Zhang, K.; Tanaka, Y.; Gillis, J.; Ting, J. T.; Ben-Simon, Y.; Miller, J.; Ecker, J. R.; Ren, B.; Aerts, S.; Lein, E. S.; Tasic, B.; Bakken, T. E.
10.1101/2024.08.21.609075 — genomics — Posted on 2024-08-21
1682 Reconstructing prevalence dynamics of wildlife pathogens from pooled and individual samples
Borremans, B.; Falvo, C. A.; Crowley, D. E.; Hoegh, A.; Lloyd-Smith, J. O.; Peel, A. J.; Restif, O.; Ruiz-Aravena, M.; Plowright, R. K.
10.1101/2023.11.02.565200 — ecology — Posted on 2024-08-22
1683 Appendage regeneration requires IMPDH2 and creates a sensitized environment for enzyme filament formation
McCartney, M. E.; Wheeler, G. M.; O'Neill, A. G.; Patel, J. H.; Litt, Z. R.; Calise, S. J.; Kollman, J. M.; Wills, A. E.
10.1101/2024.07.29.605679 — developmental biology — Posted on 2024-08-21
1684 Deciphering Pre-existing and Induced 3D Genome Architecture Changes involved in Constricted Melanoma Migration
Playter, C.; Golloshi, R.; Garretson, J. H.; Gonzalez, A. R.; Olajide, T. H.; Saad, A.; Benson, S. J.; McCord, R. P.
10.1101/2024.08.21.609017 — cell biology — Posted on 2024-08-22
1685 Specific pre-plasma cell states and local proliferation at the dark zone - medulla interface characterize germinal center-derived plasma cell differentiation in lymph node
Binet, L.; Dong, C.; Attaf, N.; Gil, L.; Fallet, M.; Boudier, T.; Escaliere, B.; Chasson, L.; Siret, C.; van de Pavert, S. A.; Navarro, J.-M.; Milpied, P.
10.1101/2024.07.26.605240 — immunology — Posted on 2024-08-22
1686 Effective excitability captures network dynamics across development and phenotypes
Vinogradov, O.; Giannakakis, E.; Buendia, V.; Uysal, B.; Ron, S.; Weinreb, E.; Schwarz, N.; Lerche, H.; Moses, E.; Levina, A.
10.1101/2024.08.21.608974 — neuroscience — Posted on 2024-08-21
1687 Learning reshapes the hippocampal representation hierarchy
Chiossi, H. S. C.; Nardin, M.; Tkacik, G.; Csicsvari, J. L.
10.1101/2024.08.21.608911 — neuroscience — Posted on 2024-08-21
1689 A Hippocampal-parietal Network for Reference Frame Coordination
Zheng, Y.; Zhou, X.; Moseley, S. C.; Ragsdale, S. M.; Alday, L. J.; Wu, W.; Wilber, A. A.
10.1101/2024.08.21.609019 — neuroscience — Posted on 2024-08-21
1690 Selective direct motor cortical influence during naturalistic climbing
Koh, N.; Ma, Z.; Sarup, A.; Kristl, A. C.; Agrios, M.; Young, M.; Miri, A.
10.1101/2023.06.18.545509 — neuroscience — Posted on 2024-08-21
1692 Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex
Jamali, S.; Bagur, S.; Bremont, E.; Van Kerkoerle, T.; Dehaene, S.; Bathellier, B.
10.1101/2024.08.21.609026 — neuroscience — Posted on 2024-08-22
1693 Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia
Abou Alaiwa, M. H.; Hilkin, B. M.; Price, M. P.; Gansemer, N. D.; Rector, M. R.; Stroik, M. R.; Powers, L. S.; Whitworth, K. M.; Samuel, M. S.; Jain, A.; Ostedgaard, L. S.; Ernst, S. E.; Philibert, W.; Boyken, L. D.; Moninger, T. O.; Karp, P. H.; Hornick, D. B.; Sinn, P. L.; Fischer, A. J.; Pezzulo, A. A.; McCray, P. B.; Meyerholz, D. K.; Zabner, J.; Prather, R. S.; Welsh, M. J.; Stoltz, D. A.
10.1101/2024.05.22.594822 — physiology — Posted on 2024-08-21
1697 Conventional therapy induces tumor immunoediting and modulates the immune contexture in colorectal cancer
Fotakis, G.; Rieder, D.; Loncova, Z.; Carollo, S.; Klieser, E.; Neureiter, D.; Huemer, F.; Hoegler, S.; Tomberger, M.; Krogsdam, A.; Kenner, L.; Ziegler, P. K.; Greil, R.; Weiss, L.; Trajanoski, Z.
10.1101/2024.08.21.608938 — cancer biology — Posted on 2024-08-21
1698 Covalently linked adenovirus-AAV complexes as a novel platform technology for gene therapy
Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lagor, W.; Bao, G.; Lu, Z. H.; Curiel, D. T.
10.1101/2024.08.21.609008 — synthetic biology — Posted on 2024-08-21
1700 Unsupervised domain classification of AlphaFold2-predicted protein structures
Barone, F.; Laio, A.; Punta, M.; Cozzini, S.; Ansuini, A.; Cazzaniga, A.
10.1101/2024.08.21.608992 — bioinformatics — Posted on 2024-08-21
1701 Context-specific inhibition of mitochondrial ribosomes by phenicol and oxazolidinone antibiotics
Bibel, B.; Raskar, T.; Couvillion, M.; Lee, M.; Kleinman, J. I.; Takeuchi-Tomita, N.; Churchman, L. S.; Fraser, J. S.; Fujimori, D. G.
10.1101/2024.08.21.609012 — biochemistry — Posted on 2024-08-21
1702 Ionizable networks mediate pH-dependent allosteryin SH2 signaling proteins
Van Dyck, P. K.; Piszkin, L.; Gorski, E. A.; Tartarella Nascimento, E.; Abebe, J. A.; Hoffmann, L. M.; Peng, J. W.; White, K. A.
10.1101/2024.08.21.608875 — biochemistry — Posted on 2024-08-21
1705 Conserved RNA-binding protein interactions mediate syntologous lncRNA functions
Sabate-Cadenas, X.; Lavalou, P.; Ross, C. J.; Chen, L.; Zielinski, D.; Vacher, S.; Ledevin, M.; Larcher, T.; Petitjean, M.; Damy, L.; Servant, N.; Bieche, I.; Ulitsky, I.; Shkumatava, A.
10.1101/2024.08.21.605776 — molecular biology — Posted on 2024-08-21
1707 Grin1Y647S/+ Mice: A Preclinical Model of GRIN1-Related Neurodevelopmental Disorder
Sullivan, M. T.; Tidball, P.; Yan, Y.; Intson, K.; Chen, W.; Xu, Y.; Venkatesan, S.; Horsfall, W.; Georgiou, J.; Finnie, P. S. B.; Lambe, E. K.; Traynelis, S. F.; Salahpour, A.; Yuan, H.; Collingridge, G. L.; Ramsey, A. J.
10.1101/2024.08.21.608984 — neuroscience — Posted on 2024-08-21
1708 Magnetic Activation of Spherical Nucleic Acids for the Remote Control of Synthetic Cells
Parkes, E.; Al Samad, A.; Mazzotti, G.; Newell, C.; Ng, B.; Radford, A.; Booth, M. J.
10.1101/2024.08.21.608917 — synthetic biology — Posted on 2024-08-21
1710 Fc-independent SARS-CoV-2 infection-enhancing antibodies decouple N-terminal and receptor-binding domains by cross-linking neighboring spikes
van Eerden, F. J.; Li, S.; Lusiany, T.; Ismanto, H. S.; Terada, T.; Gerle, C.; Akamatsu, K.; Hirose, M.; Sugihara, F.; Chen, D. V.; Kishikawa, J.-i.; Kato, T.; Liu, Y.; Okada, M.; Arase, H.; Standley, D. M.
10.1101/2024.08.21.608921 — molecular biology — Posted on 2024-08-21
1712 Large serine integrases utilise scavenged phage proteins as directionality cofactors
Alsaleh, A.; Pena Reyes, T.; Baksh, A.; Taiwo-Aiyerin, O. T.; Holland, A.; Pigli, Y. Z.; Rice, P. A.; Olorunniji, F. J.
10.1101/2024.08.21.608926 — molecular biology — Posted on 2024-08-21
1714 Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response
Lee, A. A.; Amick, I.; Aschenbrenner, J. C.; Barr, H. A.; Benjamin, J.; Brandis, A.; Cohen, G.; Diaz-Tapia, R.; Duberstein, S.; Dixon, J.; Cousins, D.; Fairhead, M.; Fearon, D.; Frick, J.; Gayvert, J.; de Godoy, A. S.; Griffen, E. J.; Huber, K. V. M.; Koekemoer, L.; Lahav, N.; Marples, P. G.; McGovern, B. L.; Mehlman, T.; Robinson, M. C.; Singh, U.; Szommer, T.; Tomlinson, C. W. E.; Vargo, T.; von Delft, F.; Wang, S.; White, K. M.; Williams, E.; Winokan, M.
10.1101/2024.08.19.608619 — microbiology — Posted on 2024-08-21
1715 Exploring the diversity of anti-defense systems across prokaryotes, phages, and mobile genetic elements
Tesson, F.; Huiting, E.; Wei, L.; Ren, J.; Johnson, M. C.; Planel, R.; Cury, J.; Feng, Y.; Bondy-Denomy, J.; Bernheim, A.
10.1101/2024.08.21.608784 — microbiology — Posted on 2024-08-21
1719 Escape of SARS-CoV-2 variants KP1.1, LB.1 and KP3.3 from approved monoclonal antibodies
Planas, D.; Staropoli, I.; Planchais, C.; Yab, E.; Jeyarajah, B.; Rahou, Y.; Guivel-Benhassine, F.; Prot, M.; Lemoine, F.; Enouf, V.; Simon-Loriere, E.; Mouquet, H.; Rameix-Welti, M.-A.; Schwartz, O.
10.1101/2024.08.20.608835 — immunology — Posted on 2024-08-21
1720 Aging and viral evolution impair immunity against dominant pan-coronavirus-reactive T cell epitope
Loyal, L.; Juerchott, K.; Reimer, U.; Meyer-Arndt, L.; Henze, L.; Mages, N.; Kostrzanowski, J.; Reus, B.; Mangold, M.; Kruse, B.; Dingeldey, M.; Sawitzki, B.; Wenschuh, H.; Michel, J.; Grossegesse, M.; Nitsche, A.; Lachmann, N.; Timmermann, B.; Giesecke, C.; Braun, J.; Kern, F.; Thiel, A.
10.1101/2024.08.21.608923 — immunology — Posted on 2024-08-21
1722 Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity
Alharithi, Y. J.; Phillips, E. A.; Wilson, T. D.; Couvillion, S. P.; Nicora, C. D.; Darakjian, P.; Rakshe, S.; Fei, S. S.; Counts, B.; Metz, T. O.; Searles, R.; Kumar, S.; Maloyan, A.
10.1101/2024.08.20.608809 — molecular biology — Posted on 2024-08-21
1725 Benchmarking macaque brain gene expression for horizontal and vertical translation
Luppi, A. I.; Liu, Z.-Q. I.; Hansen, J. Y.; Cofre, R.; Kuzmin, E.; Froudist-Walsh, S.; Palomero-Gallagher, N.; Misic, B.
10.1101/2024.08.18.608440 — neuroscience — Posted on 2024-08-21
1726 Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis over a day:night cycle
Malik, D. M.; Rhoades, S. D.; Zhang, S. L.; Sengupta, A.; Barber, A.; Haynes, P.; Arnadottir, E. S.; Pack, A.; Kibbey, R. G.; Kain, P.; Sehgal, A.; Weljie, A. M.
10.1101/2023.10.30.564837 — systems biology — Posted on 2024-08-21
1727 Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells
Tourneur, A.; Rodrigues Vitoria, J.; Saiselet, M.; Craciun, L.; Larsimont, D.; Lefort, A.; Libert, F.; Maenhaut, C.; Costagliola, S.; Tarabichi, M.; Romitti, M.; Detours, V.
10.1101/2024.02.15.580495 — cancer biology — Posted on 2024-08-21
1728 Interplay of condensate material properties and chromatin heterogeneity governs nuclear condensate ripening
Banerjee, D. S.; Chigumira, T.; Lackner, R. M.; Kratz, J. C.; Chenoweth, D. M.; Banerjee, S.; Zhang, H.
10.1101/2024.05.07.593010 — biophysics — Posted on 2024-08-21
1730 Adaptation to space conditions of novel bacterial species isolated from the International Space Station revealed by functional gene annotations and comparative genome analysis
SZYDLOWSKI, L. M.; Bulbul, A.; Simpson, A. C.; Kaya, D. E.; Singh, N. K.; Sezerman, U. O.; Labaj, P. P.; Kosciolek, T.; Venkateswaran, K.
10.1101/2023.09.28.559980 — bioinformatics — Posted on 2024-08-21
1731 Circulating (poly)phenol metabolites in the brain: unveiling in vitro and in vivo blood-brain barrier transport
Carecho, R.; Marques, D.; Carregosa, D.; Masuero, D.; Garcia-Aloy, M.; Tramer, F.; Passamonti, S.; Vrhovsek, U.; Ventura, R.; Brito, M. A.; Nunes dos Santos, C.; Figueira, I.
10.1101/2024.02.27.582339 — biochemistry — Posted on 2024-08-21
1734 Urinary Sodium Wasting and Disrupted Collecting Duct Function in Mice with dRTA-Causing SLC4A1 Mutations
Mungara, P.; MacNaughton, K.; Ullah, A. S.; Essuman, G.; Chelangarimiyandoab, F.; Mumtaz, R.; Hennings, J. C.; Hubner, C. A.; Eladari, D.; Alexander, R. T.; Cordat, E.
10.1101/2024.08.21.608692 — physiology — Posted on 2024-08-21
1735 Gender and speech material effects on the long-term average speech spectrum, including at extended high frequencies
Delaram, V.; Miller, M. K.; Ananthanarayana, R. M.; Trine, A.; Buss, E.; Stecker, G. C.; Monson, B. B.
10.1101/2024.08.21.607381 — biophysics — Posted on 2024-08-21
1737 Decoding multicellular niche formation in the tumour microenvironment from nonspatial single-cell expression data
Yu, C.; Geuenich, M. J.; Ge, S.; Jang, G.-H.; Ju, T. T.; Zhang, A.; O'Kane, G.; Notta, F.; Campbell, K. R.
10.1101/2024.08.21.608956 — bioinformatics — Posted on 2024-08-21
1738 Insights from Molecular Docking and Dynamics Simulations of P2RX7-????Syn Complex
singh, K.; Joshi, J.; Sharma, S.; Irungbam, K. D.; Kumar, A.; Saini, M.; Kumar, M.
10.1101/2024.08.21.608916 — bioinformatics — Posted on 2024-08-21
1740 PriMAT: A robust multi-animal tracking model for primates in the wild
Vogg, R.; Nuske, M.; Weis, M. A.; Luddecke, T.; Karakoc, E.; Ahmed, Z.; Pereira, S.; Malaivijitnond, S.; Meesawat, S.; Worgotter, F.; Kappeler, P. M.; Gail, A.; Ostner, J.; Schulke, O.; Fichtel, C.; Ecker, A. S.
10.1101/2024.08.21.607881 — animal behavior and cognition — Posted on 2024-08-21
1742 Wolbachia introgression in Ae. aegypti is accompanied by variable loss - a multi-country assessment
Dainty, K. R.; Pacidonio, E. C.; Lee, E.; Kyrylos, P. K.; Baran, N.; Kay, E.; Dong, Y.; Pinto, S. B.; Ribeiro, G. S.; Uribe, A.; Barajas, J.; O'Neill, S. L.; Velez, I. D.; Moreira, L. A.; Simmons, C. P.; Flores, H. A.
10.1101/2024.08.21.608881 — ecology — Posted on 2024-08-21
1744 Horizontal gene transfer-initiated reorganization of lipid metabolism drives lifestyle innovation in a eukaryote
Rao, B. D.; Gomez Gil, E.; Peter, M.; Balogh, G.; Nunes, V.; MacRae, J. I.; Chen, Q.; Rosenthal, P. B.; Oliferenko, S.
10.1101/2024.08.21.608818 — cell biology — Posted on 2024-08-21
1745 Characterization, enrichment, and computational modeling of cross-linked actin networks in trabecular meshwork cells
Li, H.; Harvey, D. H.; Dai, J.; Swingle, S. P.; Compton, A. M.; Sugali, C. K.; Dhamodaran, K.; Yao, J.; Lin, T.-Y.; Sulchek, T.; Kim, T.; Ethier, C. R.; Mao, W.
10.1101/2024.08.21.608970 — cell biology — Posted on 2024-08-21
1746 CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections
Rollman, T. B.; Berkebile, Z. W.; Hicks, D. M.; Hatfield, J. S.; Chauhan, P.; Pravetoni, M.; Schleiss, M. R.; Milligan, G. N.; Morgan, T. K.; Bierle, C. J.
10.1101/2024.08.21.608907 — immunology — Posted on 2024-08-21
1748 Differentiable simulation enables large-scale training of detailed biophysical models of neural dynamics
Deistler, M.; Kadhim, K. L.; Pals, M.; Beck, J.; Huang, Z.; Gloeckler, M.; Lappalainen, J. K.; Schröder, C.; Berens, P.; Goncalves, P. J.; Macke, J. H.
10.1101/2024.08.21.608979 — neuroscience — Posted on 2024-08-21
1749 Spatial and morphological organization of mitochondria across a connectome
Sager, G.; Pallasdies, F. C.; Gowers, R.; Ravikumar, S.; Wu, E.; Colon-Ramos, D.; Schreiber, S.; Clark, D. A.
10.1101/2024.08.21.608912 — neuroscience — Posted on 2024-08-21
1754 Mll4 regulates tooth enamel development
Lee, J.-M.; Jung, H.; Tang, Q.; An, W.; Lee, S.-K.; Lee, J. W.; Kwon, H.-J.
10.1101/2024.08.20.608898 — developmental biology — Posted on 2024-08-21
1755 In utero human intestine contains maternally derived bacterial metabolites
Wang, W.; Gu, W.; Schweitzer, R.; Koren, O.; Khatib, S.; Tseng, G.; Konnikova, L.
10.1101/2024.08.20.608888 — microbiology — Posted on 2024-08-21
1760 Behavioral and neural correlates of diverse conditioned fear responses in male and female rats
Mitchell, J.; Vincelette, L.; Tuberman, S.; Sheppard, V.; Bergeron, E.; Calitri, R.; Clark, R.; Cody, C. R.; Kannan, A.; Keith, J.; Parakoyi, A.; Pikus, M.; Vance, V.; Ziane, L.; Brenhouse, H.; Laine, M.; Shansky, B.
10.1101/2024.08.20.608817 — neuroscience — Posted on 2024-08-21
1761 ER stress-induced TREM2 downregulation exacerbates platelet activation and myocardial infarction in patients with coronary artery disease
Wu, X.; Pan, G.; Chang, L.; Zhang, Y.; Liu, Y.; Zhang, W.; Guo, Y.; Zhang, G.; Zhong, H.; Qi, Z.; Zhang, J.; Xue, R.; Chen, S.; Hu, H.; Dong, J.; Zhang, S.; Ding, Z.
10.1101/2024.08.20.608887 — pharmacology and toxicology — Posted on 2024-08-21
1765 Resolving interface structure and local internal mechanics of mitotic chromosomes
Ridolfi, A.; Witt, H.; Harju, J.; Clement, T. V. M.; Peterman, E.; Broedersz, C.; Wuite, G. J. L.
10.1101/2024.08.20.608279 — biophysics — Posted on 2024-08-21
1768 Characterizing the role of exosomal miRNAs in metastasis
Agrawal, P.; Olgun, G.; Singh, A.; Gopalan, V.; Hannenhalli, S.
10.1101/2024.08.20.608894 — bioinformatics — Posted on 2024-08-21
1770 Understanding responses to multi-electrode epiretinal stimulation using a biophysical model
Vilkhu, R. S.; Vasireddy, P. K.; Kish, K. E.; Gogliettino, A. R.; Lotlikar, A.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Mitra, S.; Chichilnisky, E. J.
10.1101/2024.08.20.608829 — bioengineering — Posted on 2024-08-21
1772 Broad bandwidth photoacoustic imaging using a PVDF receiver array
Chandramoorthi, S.; Lopez Marin, A.; Beurskens, R.; van der Steen, A. F. W.; van Soest, G.
10.1101/2024.08.20.608753 — bioengineering — Posted on 2024-08-21
1776 Emergence of antibiotic-specific Mycobacterium tuberculosis phenotypes during prolonged treatment of mice
Wynn, E. A.; Dide-Agossou, C.; Al Mubarak, R.; Rossmassler, K.; Ektnitphong, V.; Bauman, A. A.; Massoudi, L. M.; Voskuil, M. I.; Robertson, G. T.; Moore, C. M.; Walter, N. D.
10.1101/2024.08.20.607990 — genomics — Posted on 2024-08-21
1778 A Flexible Framework for Assessing the Cumulative Effects of Offshore Wind Energy Activities and Other Pressures on Aerofauna
Furguson, M. C.; Williams, K. A.; Goodale, M. W.; Adams, E. M.; Knaga, P.; Kingdon, K.; Avery-Gomm, S.
10.1101/2024.08.20.608171 — ecology — Posted on 2024-08-21
1780 Nonlinear thinking in ecology and evolution: The case for ecological scaling of the Threshold Elemental Ratio
Tumolo, B.; Olson, C.; Larson, E.; Halvorson, H.; Wagner, C. E.; Krist, A.; Osburn, F.; Moody, E.; Rock, L.; Ogbenna, U.; Wess, E.; Najev, B. L.; Pignatelli, A.; Corman, J.
10.1101/2024.08.20.608290 — ecology — Posted on 2024-08-21
1781 Morphogenic, molecular, and cellular adaptations for unidirectional airflow in the chicken lung
Gerner-Mauro, K. N.; Ellis, L. V.; Wang, G.; Nayak, R.; Lwigale, P. Y.; Poche, R. A.; Chen, J.
10.1101/2024.08.20.608866 — developmental biology — Posted on 2024-08-21
1782 The microbiota affects stem cell decision making in Hydra
He, J.; Klimovich, A.; Kock, S.; Dahmke, L.; Franzenburg, S.; Bosch, T. C. G.
10.1101/2024.08.20.608462 — developmental biology — Posted on 2024-08-21
1783 CryoSCAPE: Scalable Immune Profiling Using Cryopreserved Whole Blood for Multi-omic Single Cell and Functional Assays
Heubeck, A. T.; Phalen, C.; Kaul, N.; Wittig, P. J.; Garber, J.; Weiss, M.; Genge, P. C.; Thomson, Z.; Gustafson, C.; Reading, J.; Skene, P. J.
10.1101/2024.08.20.608826 — immunology — Posted on 2024-08-21
1786 Transcriptional Dynamics of Sleep Deprivation and Subsequent Recovery Sleep in the Male Mouse Cortex
Popescu, A.; Ottaway, C.; Ford, K.; Patterson, T. W.; Ingiosi, A. M.; Medina, E.; Hicks, S. C.; Singletary, K.; Peixoto, L.
10.1101/2024.08.20.607983 — neuroscience — Posted on 2024-08-21
1787 Anti-NMDAR encephalitis alters intrinsic spatiotemporal coding by enhancing neuronal coupling and clustering
Rahmati, V.; Graf, J.; Ceanga, M.; Rivera, D. C.; Haselmann, H.; Liebscher, S.; Prüss, H.; Holthoff, K.; Kirmse, K.; Geis, C.
10.1101/2024.08.20.608793 — neuroscience — Posted on 2024-08-21
1789 Immediate TMS-EEG responses reveal motor cortex excitability
Stango, A.; Zazio, A.; Barchiesi, G.; Dognini, E.; Marcantoni, E.; Bortoletto, M.
10.1101/2024.08.20.608770 — neuroscience — Posted on 2024-08-21
1793 An in vivo screen identifies NAT10 as a master regulator of brain metastasis
Chen, J. F.; Xu, P.; Cai, W. L.; Chen, H.; Wingrove, E.; Li, W.; Biancon, G.; Zhang, M.; Balabaki, A.; Krop, E. D.; Zhang, Y.; Yin, M.; Tebaldi, T.; Meier, J. L.; Westbrook, T. F.; Halene, S.; Liu, Y.; Nguyen, D.; Yan, Q.
10.1101/2024.08.20.608711 — cancer biology — Posted on 2024-08-21
1799 Three Open Questions in Polygenic Score Portability
Wang, J. Y.; Lin, N.; Zietz, M.; Mares, J.; Narasimhan, V. M.; Rathouz, P. J.; Harpak, A.
10.1101/2024.08.20.608703 — genetics — Posted on 2024-08-21
1801 Extracellular Vesicle-Associated Neutrophil Elastase Activates Hepatic Stellate Cells and Promotes Liver Fibrogenesis via ERK1/2 Pathway
Oshins, R.; Greenberg, Z.; Tai, Y.-L.; Zhao, D.; Wang, X.; Mehrad, B.; He, M.; Patel, I.; Khartabil, L.; Zhou, H.; Brantly, M.; Khodayari, N.
10.1101/2024.08.20.608832 — cell biology — Posted on 2024-08-21
1802 Data acquisition strategies to reduce cardiac-induced noise in brain maps of R2* and magnetic susceptibility
Raynaud, Q.; Dardano, T.; Oliveira, R.; Di Domenicantonio, G.; Tobias, T.; Roy, C. W.; van Heeswijk, R. B.; Lutti, A.
10.1101/2024.08.20.608759 — neuroscience — Posted on 2024-08-21
1805 Neural dynamics of visual streams interactions during memory-guided actions investigated by intracranial EEG
Moraresku, S.; Hammer, J.; Dimakopoulos, V.; Kajsova, M.; Janca, R.; Jezdik, P.; Kalina, A.; Marusic, P.; Vlcek, K.
10.1101/2024.08.20.608807 — neuroscience — Posted on 2024-08-21
1807 Unified Mass Imaging Maps the Lipidome of Vertebrate Development
Schede, H. H.; Haj Abdullah Alieh, L.; Rohde, L.; Hererra, A.; Schlaeppi, A.; Valentin, G.; Motlagh, A. G.; Dominguez Mantes, A. H.; Jollivet, C.; Paz Montoya, J.; Capolupo, L.; Khven, I.; Oates, A. C.; D'Angelo, G.; La Manno, G.
10.1101/2024.08.20.608739 — systems biology — Posted on 2024-08-21
1808 Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels
Chester, M.; Devillers, M. M.; Corre, R.; Giton, F.; Souare, F.; Petrovic, C.-H.; Airaud, E.; Quintas, D.; Mhouty-Kodja, S.; Naule, L.; Guigon, C. J.
10.1101/2024.08.20.608775 — physiology — Posted on 2024-08-21
1809 Low extracellular pH protects cancer cells from ammonia toxicity.
Mejlvang, J.; Dravecka, M.; Mikkola, I.; Johansen, T.; Seternes, O. M.
10.1101/2024.08.20.608758 — cancer biology — Posted on 2024-08-21
1810 Genetic underpinnings of predicted changes in cardiovascular function using self supervised learning
Levine, Z.; Lutsker, G.; Godneva, A.; Weinberger, A.; Lotan-Pompan, M.; Talmor-Barkan, Y.; Reisner, Y.; Rossman, H.; Segal, E.
10.1101/2024.08.15.608061 — systems biology — Posted on 2024-08-21
1811 Enabling Transparent Toxicokinetic Modeling for Public Health Risk Assessment
Davidson-Fritz, S. E.; Ring, C. L.; Schacht, C. M.; Evans, M. V.; Chang, X.; Breen, M.; Honda, G. S.; Kenyon, E.; Linakis, M. W.; Meade, A.; Pearce, R. G.; Sfeir, M. A.; Sluka, J. P.; Devito, M. J.; Wambaugh, J. F.
10.1101/2024.08.19.608571 — pharmacology and toxicology — Posted on 2024-08-21
1815 Optimization of TMS target engagement: novel evidence based on combined TMS-EEG and dMRI tractography of brain circuitry
Lioumis, P.; Roine, T.; Grano, I.; Aydogan, D. B.; Ukharova, E.; Souza, V. H.; Kicic, D.; Ilmoniemi, R.; Makris, N.
10.1101/2024.08.19.607213 — neuroscience — Posted on 2024-08-21
1818 Large scale comparative wheat phosphoproteome profiling pinpoints temperature-associated molecular signatures
Fonseca de Lima, C. F.; Zhu, T.; Van den Broeck, L.; Van De Cotte, B.; Locke, A. M.; Sozzani, R.; De Smet, I.
10.1101/2024.08.20.608123 — plant biology — Posted on 2024-08-21
1820 Endophytic pyrroloquinoline quinone enhances banana growth and immunity against Fusarium wilt for plant-microbe mutualisms
Hung, S.-H. W.; Yu, M.-Y.; Liu, C.-H.; Huang, T.-C.; Peng, J.-H.; Jang, N.-Y.; Kuo, C.-H.; Ho, Y.-N.; Chiang, E.-P. I.; Hwang, H.-H.; Huang, C.-C.
10.1101/2024.08.20.608638 — plant biology — Posted on 2024-08-21
1822 Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family
Merello, G.; Olivares-Costa, M.; Basile, L.; Pastor, T. P.; Mendoza-Soto, P.; Padilla-Santiago, L.; Mardones, G.; Binda, C.; Opazo, J. C.
10.1101/2024.08.20.608864 — evolutionary biology — Posted on 2024-08-21
1825 Multi-layered dosage compensation of the avian Z chromosome
Papanicolaou, N.; Lentini, A.; Wettersten, S.; Hagemann-Jensen, M.; Kruger, A.; Zhang, J.; Coucoravas, C.; Petrosian, I.; Xin, X.; Ceyhan, I.; Rorbach, J.; Wright, D.; Reinius, B.
10.1101/2024.08.20.608780 — molecular biology — Posted on 2024-08-21
1826 A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin
Skribbe, M.; Soneson, C.; Stadler, M. B.; Schwaiger, M.; Suma Sreechakram, V. N.; Iesmantavicius, V.; Hess, D.; Pandini Figueiredo Moreno, E.; Braun, S.; Seebacher, J.; Smallwood, S. A.; Buhler, M.
10.1101/2024.08.20.607873 — molecular biology — Posted on 2024-08-21
1827 Embryo-restricted responses to maternal IL-17A promote neurodevelopmental disorders in mouse offspring
Andruszewski, D.; Uhlfelder, D. C.; Desiato, G.; Regen, T.; Blanfeld, M.; Schelmbauer, C.; Scherer, L.; Radyushkin, K.; Pozzi, D.; Waisman, A.; Mufazalov, I. A.
10.1101/2023.12.25.573296 — neuroscience — Posted on 2024-08-21
1828 Identification of phenotypic and transcriptomic signatures underpinning maize crown root systems
Callwood, J. B.; Townsend, E. G.; Malik, S.; Draves, M. A.; Khor, J.; Marshall, J. P.; Sweers, H.; Cowling, C. L.; Walley, J. W.; Kelley, D. R.
10.1101/2024.08.20.608626 — plant biology — Posted on 2024-08-21
1829 Ferroptosis susceptibility of melanoma cells: dependence on cell-type, acquired drug resistance, and medium composition
Preis, J. R.; Rolvering, C.; Kirchmeyer, M.; Halilovic, D.; Wroblewska, J. P.; Tolle, F.; Behrmann, I.; Haan, C.
10.1101/2024.08.12.607529 — cancer biology — Posted on 2024-08-21
1833 Deep Learning and GBLUP Integration: An Approach that Identifies Nonlinear Genetic Relationships Between Traits
Shokor, F.; Croiseau, P.; Gangloff, H.; Saintilan, R.; Tribout, T.; Mary-Huard, T.; C.D Cuyabano, B.
10.1101/2024.03.23.585208 — genomics — Posted on 2024-08-21
1835 Boosting Proteasome Activity: A Novel Mechanism of NMDAR Blockers Against Neurodegeneration
Sahin, F.; Gunel, A.; Atasoy, B. T.; Guler, U.; Salih, B.; Kuzu, I.; Taspinar, M.; Cinar, O.; Kahveci, S.
10.1101/2024.08.20.608787 — neuroscience — Posted on 2024-08-21
1837 Transcriptional and epigenetic response of rapeseed (Brassica napus L.) to PEG-triggered osmotic stress
Prasad, M.; Shetty, P.; Pal, A.; Kant, K.; Nagy, I.; Shivaprasad, P. V.; Szabados, L.; Rigo, G.; Zsigmond, L.
10.1101/2024.08.19.608641 — plant biology — Posted on 2024-08-21
1838 Transcriptomic profiling of gill biopsies to define predictive markers for seawater survival in farmed Atlantic salmon
Gronvold, L.; Dalum, M. J.; Striberny, A.; Manousi, D.; Ytrestoyl, T.; Morkore, T.; Boison, S.; Gjerde, B.; Jorgensen, E.; Sandve, S. R.; Hazlerigg, D.
10.1101/2024.08.20.608748 — genomics — Posted on 2024-08-21
1839 Impaired DNA damage response and inflammatory signalling underpins hematopoietic stem cell defects in Gata2 haploinsufficiency
Abdelfattah, A.; Habib, A.; Thomas, L.-a.; Menendez-Gonzalez, J. B.; Almotiri, A.; Alqahtani, H.; Lawson, H.; Taha, S.; Steadman, M.; Athalye, R.; Gibbs, A.; Alzahrani, H.; Cato, A.; Giles, P.; Tonks, A.; Boyd, A. S.; Kranc, K. R.; Rodrigues, N.
10.1101/2024.08.20.608056 — cancer biology — Posted on 2024-08-21
1840 CLEAR-IT: Contrastive Learning to Capture the Immune Composition of Tumor Microenvironments
Spengler, D.; Korovin, S.; Prakash, K.; Bankhead, P.; Debets, R.; Smith, C.; Balcioglu, H. E.
10.1101/2024.08.20.608738 — bioinformatics — Posted on 2024-08-21
1841 Endoplasmic reticulum patterns insect cuticle nanostructure
Inagaki, S.; Wada, H.; Itabashi, T.; Itakura, Y.; Nakagawa, R.; Chen, L.; Murata, K.; Iwane, A. H.; Hayashi, S.
10.1101/2024.08.20.608717 — developmental biology — Posted on 2024-08-21
1844 Dev-Atlas: A reference atlas of functional brain networks for typically developing adolescents
Doucet, G.; Goldsmith, C.; Myers, K.; Rice, D.; Ende, G.; Pavelka, D. J.; Joliot, M.; Calhoun, V.; Wilson, T. W.; Uddin, L. Q.
10.1101/2024.08.20.608658 — neuroscience — Posted on 2024-08-20
1845 Nicotine engages a VTA-NAc feedback loop to inhibit amygdala-projecting dopamine neurons and induce anxiety.
Marti, F.; Faure, P.; Le Borgne, T.; Nguyen, C.; Vicq, E.; Jehl, J.; Solie, C.; Guyon, N.; Daussy, L.; Gulmez, A.; Reynolds, L.; Mondoloni, S.; Tolu, S.; Pons, S.; Maskos, U.; Valjent, E.; Mourot, A.
10.1101/2024.08.20.607920 — neuroscience — Posted on 2024-08-20
1848 Re-evaluating the relationship between female social bonds and infant survival in wild baboons
Creighton, M. J. A.; Lerch, B. A.; Lange, E. C.; Silk, J. B.; Tung, J.; Archie, E. A.; Alberts, S. C.
10.1101/2024.08.20.608854 — animal behavior and cognition — Posted on 2024-08-20
1849 Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family
Merello, G.; Olivares-Costa, M.; Basile, M.; Pastor, T. P.; Mendoza-Soto, P.; Padilla-Santiago, L.; Mardones, G.; Binda, C.; Opazo, J. C.
10.1101/2024.08.20.608864 — evolutionary biology — Posted on 2024-08-20
1850 p53 mediated regulation of LINE1 retrotransposon derived R-loops
Paul, P.; Kumar, A.; De, A. K.; Parida, A. S.; Bhadke, G. V.; Khatua, S.; Pattanayak, F.; Tiwari, B.
10.1101/2024.04.12.589154 — cancer biology — Posted on 2024-08-20
1852 Structure of the T=13 capsid of infectious pancreatic necrosis virus (IPNV) - a salmonid birnavirus
Munke, A.; Ahmed Abdelrahim Gamil, A.; Mikalsen, A. B.; Wang, H.; Evensen, O.; Okamoto, K.
10.1101/2024.08.20.608766 — biophysics — Posted on 2024-08-20
1856 A unified theoretical framework for invasion in host-symbiont communities
Martignoni, M. M.; Garnier, J. M.; Tyson, R. C.; Harris, K. D.; Kolodny, O.
10.1101/2024.01.18.576278 — ecology — Posted on 2024-08-20
1858 Multi-layered dosage compensation of the avian Z chromosome
Papanicolaou, N.; Lentini, A.; Wettersten, S.; Hagemann-Jensen, M.; Kruger, A.; Zhang, J.; Coucoravas, C.; Petrosian, I.; Xin, X.; Ceyhan, I.; Rorbach, J.; Wright, D.; Reinius, B.
10.1101/2024.08.20.608780 — molecular biology — Posted on 2024-08-20
1859 Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity
Alharithi, Y. J.; Phillips, E. A.; Wilson, T. D.; Couvillion, S. P.; Nicora, C. D.; Darakjian, P.; Rakshe, S.; Fei, S. S.; Counts, B.; Zimmers, T.; Metz, T. O.; Searles, R.; Kumar, S.; Maloyan, A.
10.1101/2024.08.20.608809 — molecular biology — Posted on 2024-08-20
1862 Multivalent administration of dengue E dimers on liposomes elicits type-specific neutralizing responses without immune interference
Phan, T. T. N.; Hvasta, M. G.; Thiono, D. J.; Shah, R. P.; Ajo, G. P.; Huang, W.-c.; Lovell, J.; Tian, S.; de Silva, A. M.; Kuhlman, B.
10.1101/2024.08.20.608851 — microbiology — Posted on 2024-08-20
1864 PRRSV-2 variant classification: a dynamic nomenclature for enhanced monitoring and surveillance
VanderWaal, K.; Pamornchainavakul, N.; Kikuti, M.; Zhang, J.; Zeller, M.; Trevisan, G.; Rossow, S.; Schwartz, M.; Linhares, D. C. L.; Holtkamp, D. J.; da Silva, J. P. H.; Corzo, C. A.; Baker, J. P.; Anderson, T. K.; Makau, D. N.; Paploski, I. A. D.
10.1101/2024.08.20.608841 — microbiology — Posted on 2024-08-20
1865 Re-programming of GM-CSF-dependent alveolar macrophages through GSK3 activity modulation
Rios, I.; Herrero, C.; Torres Torresano, M.; Lopez-Navarro, B.; Schiaffino, M. T.; Diaz Crespo, F.; Nieto-Valle, A.; Samaniego, R.; Sierra-Palomares, Y.; Oliver, E.; Revuelta, F.; Garcia-Lujan, R.; Sanchez-Mateos, P.; Delgado, R.; Puig-Kroger, A.; Corbi, A. L.
10.1101/2024.08.20.608749 — immunology — Posted on 2024-08-20
1866 Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy
Mubarak, H. F.; Tan, W.; Hoffmann, A. D.; Sun, Y.; Wei, J.; El-Shennawy, L.; Squires, J. R.; Dashzeveg, N. K.; Simonton, B.; Jia, Y.; Iyer, R.; Xu, Y.; Nicolaescu, V.; Elli, D.; Randall, G. C.; Schipma, M. J.; Swaminathan, S.; Ison, M. G.; Liu, H.; Fang, D.; Shen, Y.
10.1101/2024.03.01.582176 — immunology — Posted on 2024-08-20
1867 A neural basis for mutant ATAXIN-1 induced respiratory dysfunction in mouse models of Spinocerebellar ataxia type 1
Soles, A.; Grittner, J.; Douglas, K.; Yang, P.; Barnett, R.; Chau, C.; Cosiquien, R.; Duvick, L.; Rainwater, O.; Serres, S.; Orr, H.; Dougherty, B.; Cvetanovic, M.
10.1101/2024.08.20.608114 — neuroscience — Posted on 2024-08-20
1868 Molecular Insights into Neuronal Dysfunction in GM2 Gangliosidoses
Nicholson, A. S.; Priestman, D. A.; Antrobus, R.; Williamson, J. C.; Bush, R.; Barrow, H. G.; Smith, E.; Dobrenis, K.; Bright, N. A.; Platt, F. M.; Deane, J. E.
10.1101/2024.08.20.608810 — neuroscience — Posted on 2024-08-20
1869 Decoding reveals the neural representation of perceived and imagined musical sounds
Quiroga-Martinez, D. R.; Fernandez-Rubio, G.; Bonetti, L.; Achyutuni, K. G.; Tzovara, A.; Knight, R. T.; Vuust, P.
10.1101/2023.08.15.553456 — neuroscience — Posted on 2024-08-20
1872 Motor-driven microtubule diffusion in a photobleached dynamical coordinate system
Hirokawa, S.; Lee, H. J.; Banks, R. A.; Duarte, A. I.; Najma, B.; Thomson, M.; Phillips, R.
10.1101/2024.08.20.608861 — biophysics — Posted on 2024-08-20
1874 Enhanced metagenomics-enabled transmission inference with TRACS
Tonkin-Hill, G.; Shao, Y.; Zarebski, A. E.; Mallawaarachchi, S.; Xie, O.; Maklin, T.; Thorpe, H. A.; Davies, M. R.; Bentley, S. D.; Lawley, T. D.; Corander, J.
10.1101/2024.08.19.608527 — bioinformatics — Posted on 2024-08-20
1877 Interrelationship of substrate crystallinity, enzyme binding strength, and cellulase activity
Avelar Molina, G.; Schaller, K.; Kari, J.; Schiano-di-Cola, C.; H. J. Peters, G.; Borch, K.; Westh, P.
10.1101/2024.08.20.607150 — biochemistry — Posted on 2024-08-20
1878 Lipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome
Becker, A. p.; Biletch, E.; Kennelly, J. P.; Julio, A. R.; Villanueva, M.; Nagari, R.; Turner, D. W.; Burton, N. R.; Fukuta, T.; Cui, L.; Xiao, X.; Hong, S.-G.; Mack, J. J.; Tontonoz, P.; Backus, K.
10.1101/2024.08.20.608660 — biochemistry — Posted on 2024-08-20
1881 ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA
Soderholm, A.; Vunjak, M.; DeAlmeida, M.; Popitsch, N.; Podvalnaya, N.; Araguas-Rodriguez, P.; Scinicariello, S.; Nischwitz, E.; Butter, F.; Ketting, R.; Ameres, S. L.; Mueller-McNicoll, M.; Zuber, J.; Versteeg, G. A.
10.1101/2024.08.20.607899 — cell biology — Posted on 2024-08-20
1886 Description of Bacterial RNA Transcripts Detected in Mycobacterium tuberculosis Infected Cells from Peripheral Human Granulomas using Single Cell RNA Sequencing
Moos, P. J.; Carey, A. F.; Joseph, J.; Kialo, S.; Norrie, J.; Moyarelce, J. M.; Amof, A.; Nogua, H.; Lim, A. L.; Barrows, L. R.
10.1101/2024.08.20.608852 — microbiology — Posted on 2024-08-20
1888 Genomic loci for sclerotinia stem rot resistance and chlorophyll stability in Brassica napus: integrating GWAS with microbiome insights
Chawade, A.; Thuraga, V.; Sepp, S. S.; Ghosh, S.; Ghadamgahi, F.; Odilbekov, F.; Muthusamy, S.; Vetukuri, R. R.; Abreha, K. B.
10.1101/2024.08.20.608782 — plant biology — Posted on 2024-08-20
1891 Protein Language Models in Directed Evolution
Maguire, R.; Bloznelyte, K.; Adepoju, F.; Armean-Jones, M.; Dewan, S.; Gupta, A.; Jones, F. P.; Lalli, P.; Schooneveld, A.; Thompson, S.; Ebrahimi, E.; Fozzard, S.; Berman, D.; Rossoni, L.; Addison, W.; Taylor, I.
10.1101/2024.08.20.608752 — bioinformatics — Posted on 2024-08-20
1893 A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin
Skribbe, M.; Soneson, C.; Stadler, M. B.; Schwaiger, M.; Suma Sreechakram, V. N.; Iesmantavicius, V.; Hess, D.; Pandini Figueiredo Moreno, E.; Braun, S.; Seebacher, J.; Smallwood, S. A.; Buhler, M.
10.1101/2024.08.20.607873 — molecular biology — Posted on 2024-08-20
1895 Epigenetic control of tetrapyrrole biosynthesis by m4C DNA methylation in a cyanobacterium
Schmidt, N.; Stappert, N.; Nimura-Matsune, K.; Watanabe, S.; Sobotka, R.; Hagemann, M.; Hess, W. R.
10.1101/2024.08.20.608618 — microbiology — Posted on 2024-08-20
1897 On the identification of differentially-active transcription factors from ATAC-seq data
Gerbaldo, F. E.; Sonder, E.; Fischer, V.; Frei, S.; Wang, J.; Gapp, K.; Robinson, M. D.; Germain, P.-L.
10.1101/2024.03.06.583825 — bioinformatics — Posted on 2024-08-20
1899 Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA
Bi, Z.; Chen, Y.-X.; Young, I. D.; Su, H.; Chen, Y.; Hong, J.; Fraser, J. S.; Javid, B.
10.1101/2021.03.02.433644 — molecular biology — Posted on 2024-08-20
1901 Sleep need driven oscillation of glutamatergic synaptic phenotype
Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.
10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-08-20
1902 Neural Prioritisation of Past Solutions Supports Generalisation
Hall-McMaster, S.; Tomov, M. S.; Gershman, S. J.; Schuck, N. W.
10.1101/2024.06.10.598294 — neuroscience — Posted on 2024-08-20
1903 Duration of Morning Hyperinsulinemia Determines Hepatic Glucose Uptake and Glycogen Storage Later in the Day
Waterman, H. L.; Moore, M. C.; Smith, M.; Farmer, B.; Scott, M.; Edgerton, D. S.; Cherrington, A. D.
10.1101/2024.05.10.593551 — physiology — Posted on 2024-08-20
1906 A Highly-Efficient, Scalable Pipeline for Fixed Feature Extraction from Large-Scale High-Content Imaging Screens
Comolet, G.; Bose, N.; Winchell, J. M.; Duren-Lubancki, a.; Rusielewicz, T.; Horn, g.; Goldberg, j.; Paull, D.; Migliori, B.
10.1101/2023.07.06.547985 — cell biology — Posted on 2024-08-20
1907 Topical ABT-1 263 treatment reduces aged skin senescence and improves subsequent wound healing
Shvedova, M.; Thanapaul, R. J. R. S.; Ha, J.; Dhillon, J.; Shin, G. H.; Crouch, J.; Gower, A. C.; Gritli, S.; Roh, D. S.
10.1101/2024.08.19.608670 — cell biology — Posted on 2024-08-20
1908 Circadian clock disruption and growth of kidney cysts in autosomal dominant polycystic kidney disease
Jamadar, A.; Ward, C. J.; Remadevi, V.; Varghese, M. M.; Pabla, N. S.; Gumz, M. L.; Rao, R.
10.1101/2024.08.05.606676 — molecular biology — Posted on 2024-08-20
1913 Sniffing can be initiated by the actions of dopamine on ventral striatum neurons
Johnson, N. L.; Cotelo-Larrea, A.; Stetzik, L. A.; Akkaya, U. M.; Zhang, Z.; Gadziola, M. A.; Varga, A. G.; Ma, M.; Wesson, D. W.
10.1101/2024.02.19.581052 — neuroscience — Posted on 2024-08-20
1914 Designing host-associated microbiomes using the consumer/resource model
Plata, G. D.; Srinivasan, K.; Krishnamurthy, M.; Herron, L.; Dixit, P.
10.1101/2023.04.28.538625 — systems biology — Posted on 2024-08-20
1916 Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models
Zhang, Y.; Savvidou, M.; Liaudanskaya, V.; Ramanathan, V.; Bui, T.; Matthew, L.; Sze, A.; Ugwu, U. O.; Yuhang, F.; Matthew, D. E.; Chen, X.; Nasritdinova, S.; Dey, A.; Miller, E. L.; Kaplan, D. L.; Georgakoudi, I.
10.1101/2024.08.08.607216 — bioengineering — Posted on 2024-08-20
1919 Pollen foraging mediates exposure to dichotomous stressor syndromes in honey bees
Wizenberg, S. B.; French, S. K.; Newburn, L. R.; Pepinelli, M.; Conflitti, I. M.; Moubony, M.; Ritchie, C.; Jamieson, A.; Richardson, R. T.; Travas, A.; Imrit, M. A.; Chihata, M.; Higo, H.; Common, J.; Walsh, E. M.; Bixby, M.; Guarna, M. M.; Pernal, S. F.; Hoover, S. E.; Currie, R. W.; Giovenazzo, P.; Guzman-Novoa, E.; Borges, D.; Foster, L. J.; Zayed, A.
10.1101/2024.08.20.608746 — ecology — Posted on 2024-08-20
1921 An Infralimbic Cortex Neuronal Ensemble Encoded During Learning Attenuates Fear Generalization Expression
Subramanian, R.; Bauman, A.; Carpenter, O.; Cho, C.; Coste, G.; Dam, A.; Drake, K.; Ehnstrom, S.; Fitzgerald, N.; Jenkins, A.; Koolpe, H.; Liu, R.; Paserman, T.; Petersen, D.; Chavez, D. S.; Rozental, S.; Thompson, H.; Tsukuda, T.; Zweig, S.; Gall, M.; Zupan, B.; Bergstrom, H.
10.1101/2024.08.18.608308 — neuroscience — Posted on 2024-08-20
1923 WITHDRAWN: Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure
Lang, D.; Ni, H.; Medvedev, R.; Liu, F. V.; Tyan, L.; Turner, D.; Warden, A.; Morotti, S.; Schrauth, T.; Chanda, B.; Kamp, T. J.; Robertson, G.; Grandi, E.; Glukhov, A. V.
10.1101/2024.04.14.589457 — physiology — Posted on 2024-08-20
1929 Grains, trade and war in the multimodal transmission of Rice yellow mottle virus: an historical and phylogeographical retrospective
Ndikumana, I.; Onaga, G.; Pinel-Galzi, A.; Rocu, P.; Hubert, J.; Were, H. K.; Adego, A. K.; Were, M. N.; Poulicard, N.; Hebrard, M.; Dellicour, S.; Lemey, P.; Gilbert, E.; Dugue, M.-J.; Chevenet, F.; Bastide, P.; Guindon, S.; Fargette, D.; Hebrard, E.
10.1101/2024.08.20.608750 — evolutionary biology — Posted on 2024-08-20
1930 Tree nursery environments and their effect on early trait variation
Perry, A.; Beaton, J. K.; Stockan, J. A.; Iason, G. R.; Cottrell, J. E.; Cavers, S.
10.1101/2024.08.20.608769 — ecology — Posted on 2024-08-20
1932 Harnessing light heterogeneity to optimise controlled environment agriculture
Claydon, W.; Redmond, E. J.; Vong, G. Y.; Kluczkovski, A.; Thomas, A.; Sutton, P.; Denby, K.; Ezer, D.
10.1101/2024.08.20.608762 — plant biology — Posted on 2024-08-20
1936 Exploring mate choice and male strategies in a polymorphic moth
Selenius, E.; De Pasqual, C.; Hanninen, M.; Kartano, L.; Winters, S.; Mappes, J.
10.1101/2024.08.20.608604 — evolutionary biology — Posted on 2024-08-20
1939 GDC: An Integrated Resource to Explore the Pathogenesis of Hearing Loss through Genetics and Genomics
Cheng, H.; Wang, X.; Zhong, M.; Geng, J.; Li, W.; Pei, K.; Lu, Y.; Cheng, J.; Bu, F.; Yuan, H.
10.1101/2024.08.19.608726 — genetics — Posted on 2024-08-20
1940 High-throughput affinity measurements of direct interactions between activation domains and co-activators
DelRosso, N.; Suzuki, P.; Griffith, D.; Lotthammer, J.; Novak, B.; Kocalar, S.; Sheth, M.; Holehouse, A.; Bintu, L.; Fordyce, P.
10.1101/2024.08.19.608698 — biophysics — Posted on 2024-08-20
1941 Tesorai Search: Large pretrained model boosts identifications in mass spectrometry proteomics without the need for Percolator.
Burq, M.; Stepec, D.; Restrepo, J.; Zbontar, J.; Urazbakhtin, S.; Crampton, B.; Tiwary, S.; Miao, M.; Cox, J.; Cimermancic, P.
10.1101/2024.08.19.606805 — bioinformatics — Posted on 2024-08-20
1947 Enhanced Golden Gate Assembly: Evaluating Overhang Strength for Improved Ligation Efficiency
Strzelecki, P.; Joly, N.; Hebraud, P.; Hoffmann, E.; Cech, G. M.; Kloska, A.; Busi, F.; Grange, W.
10.1101/2022.09.09.507109 — molecular biology — Posted on 2024-08-20
1948 Halofilins as Emerging Bactofilin Families of Archaeal Cell Shape Plasticity Orchestrators
Curtis, Z.; Escudeiro, P.; Mallon, J. L.; Leland, O.; Rados, T.; Dodge, A.; Andre, K.; Kwak, J.; Yun, K.; Isaac, B.; Martinez Pastor, M.; Schmid, A.; Pohlschroder, M.; Alva, V.; Bisson, A.
10.1101/2024.01.22.576759 — microbiology — Posted on 2024-08-20
1949 High-resolution mapping of cell-cycle dynamics during T-cell development and regeneration in vivo
Kunze-Schumacher, H.; Verheyden, N. A.; Grewers, Z.; Meyer-Hermann, M.; Greiff, V.; Robert, P. A.; Krueger, A.
10.1101/2023.06.14.544919 — immunology — Posted on 2024-08-20
1950 Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function
Stolz, V.; de Freitas e Silva, R.; Rica, R.; Zhu, C.; Preglej, T.; Hamminger, P.; Hainberger, D.; Alteneder, M.; Müller, L.; Waldherr, M.; Waltenberger, D.; Hladik, A.; Agerer, B.; Schuster, M.; Frey, T.; Krausgruber, T.; Knapp, S.; Campbell, C.; Schmetterer, K.; Trauner, M.; Bergthaler, A.; Bock, C.; Boucheron, N.; Ellmeier, W.
10.1101/2022.03.24.485609 — immunology — Posted on 2024-08-20
1951 Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology
Barnett, D.; Zimmer, T. S.; Booraem, C.; Palaguachi, F.; Meadows, S. M.; Xiao, H.; Chouchani, E. T.; Orr, A. G.; Orr, A. L.
10.1101/2024.08.19.608708 — neuroscience — Posted on 2024-08-20
1953 Both major xanthophyll cycles present in nature can provide Non-Photochemical Quenching in the model diatom Phaeodactylum tricornutum
Giossi, C. E.; Wünsch, M. A.; Dautermann, O.; Schober, A. F.; Buck, J. M.; Kroth, P. G.; Lohr, M.; Lepetit, B.
10.1101/2024.03.19.584964 — plant biology — Posted on 2024-08-20
1959 Multi-Modal Large Language Model Enables Protein Function Prediction
Huo, M.; Guo, H.; Cheng, X.; Singh, D.; Rahmani, H.; Li, S.; Gerlof, P.; Ideker, T.; Grotjahn, D. A.; Villa, E.; Song, L.; Xie, P.
10.1101/2024.08.19.608729 — bioinformatics — Posted on 2024-08-20
1960 The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling
Matos-Filipe, P.; Garcia-Illarramendi, J. M.; Jorba, G.; Oliva, B.; Farres, J.; Mas, J. M.
10.1101/2022.11.10.515995 — bioinformatics — Posted on 2024-08-20
1961 Sawfish: Improving long-read structural variant discovery and genotyping with local haplotype modeling
Saunders, C. T.; Holt, J. M.; Baker, D. N.; Lake, J. A.; Belyeu, J. R.; Kronenberg, Z.; Rowell, W. J.; Eberle, M. A.
10.1101/2024.08.19.608674 — bioinformatics — Posted on 2024-08-20
1967 Enhancing Variant Calling in Whole Exome Sequencing (WES) Data Using Population-Matched Reference Genomes
Guo, S.; Huang, Z.; Zhang, Y.; He, Y.; Chen, X.; Wang, W.; Li, L.; Kang, Y.; Gao, Z.; Yu, J.; Du, Z.; Chu, Y.
10.1101/2024.08.19.608554 — genomics — Posted on 2024-08-20
1968 A single-molecule nanopore sequencing platform
Zhang, J.-Y.; Zhang, Y.; Wang, L.; Guo, F.; Yun, Q.; Zeng, T.; Yan, X.; Yu, L.; Cheng, L.; Wu, W.; Shi, X.; Chen, J.; Sun, Y.; Yang, J.; Guo, R.; Zhang, X.; Kong, L.; Wang, Z.; Yao, J.; Tan, Y.; Shi, L.; Zhao, Z.; Feng, Z.; Yu, X.; Li, C.; Zhan, W.; Ren, Y.; Yang, F.; Liu, Z.; Fan, G.; Zhong, W.; Li, D.; He, L.; Qi, Y.; Zhang, M.; Zhu, Y.; Chi, H.; Zhao, Z.; Wei, Z.; Song, Z.; Ju, Y.; Guo, R.; Xiao, L.; Lin, X.; Chen, L.; Yang, C.; Li, Q.; Wang, O.; Jin, X.; Ni, M.; Zhang, W.; Liu, L.; Gu, Y.; Wang, J.; Li, Y.; Xu, X.; Dong, Y.
10.1101/2024.08.19.608720 — genomics — Posted on 2024-08-20
1969 Latent generative modeling of long genetic sequences with GANs
Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Yelmen, B.; Jay, F.
10.1101/2024.08.07.607012 — genomics — Posted on 2024-08-20
1973 Pseudomonas aeruginosa population dynamics in a vancomycin-induced murine model of gastrointestinal carriage
Lebrun-Corbin, M.; Cheung, B.; Hullahalli, K.; dailey, k.; Bailey, K.; Waldor, M. K.; Wunderlink, R.; Bachta, K. E. R.; Hauser, A. R.
10.1101/2024.08.19.608679 — microbiology — Posted on 2024-08-20
1975 Multi-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by Bacteroides and Their Extracellular Vesicles
yousuf, b.; Mottawea, W.; Esmail, G. A.; Nazemof, N.; Bouhlel, N. E.; Njoku, E.; Li, Y.; Zhang, X.; Minic, Z.; Hammami, R.
10.1101/2024.08.19.608651 — microbiology — Posted on 2024-08-20
1979 Online movements reflect ongoing deliberation
Calalo, J. A.; Ngo, T. T.; Sullivan, S. R.; Strand, K.; Buggeln, J. H.; Lokesh, R.; Roth, A. M.; Carter, M. J.; Kurtzer, I. L.; Cashaback, J. G. A.
10.1101/2024.08.19.608669 — neuroscience — Posted on 2024-08-20
1981 Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function
Calhoun, C. C. S.; Capps, M. E. S.; Muya, K.; Gannaway, W. C.; Martina, V.; Conklin, C. L.; Klein, M. C.; Webster, J.; Torija-Olson, E. G.; Thyme, S.
10.1101/2024.08.19.608697 — neuroscience — Posted on 2024-08-20
1982 The Brain Interactome of a Permissive Prion Replication Substrate
Arshad, H.; Eid, S.; Mehra, S.; Williams, D.; Kaczmarczyk, L.; Stuart, E.; Jackson, W. S.; Schmitt-Ulms, G.; Watts, J. C.
10.1101/2024.08.19.608704 — neuroscience — Posted on 2024-08-20
1984 Abnormal activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron contributes to fructose-induced salt-sensitive hypertension
Zhang, R.; Shi, S.; Jadhav, D. A.; Kim, N.; Brostek, A.; Forester, B. R.; Shukla, R.; Qu, C.; Kramer, B.; Garvin, J. L.; Kleyman, T. R.; Gonzalez-Vicente, A.
10.1101/2024.08.19.608663 — physiology — Posted on 2024-08-20
1985 Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes
Tang, Y. J.; Xu, H.; Hughes, N. W.; Kim, S. H.; Ruiz, P.; Shuldiner, E. G.; Lopez, S. S.; Hebert, J. D.; Karmakar, S.; Andrejka, L.; Dolcen, N.; Boross, G.; Chu, P.; Detrick, C.; Pierce, S. E.; Ashkin, E. L.; Greenleaf, W.; Voss, A. K.; Thomas, T.; van de Rijn, M.; Petrov, D.; Winslow, M. M.
10.1101/2024.08.19.607671 — cancer biology — Posted on 2024-08-20
1986 Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds
Bortoluzzi, C.; Restoux, G.; Rouger, R.; Desnoues, B.; Petitjean, F.; Bosse, M.; Tixier-Boichard, M.
10.1101/2024.02.22.581528 — genomics — Posted on 2024-08-20
1987 A Human Biomimetic Intestinal Mucosa Model to Study Gastrointestinal Development and Disease
Dei, A.; Calitz, C.; Korsten, J.; Johannesson, N.; Freeze, E.; Eaves, A.; Stingl, J.; Condor, R. K.; Chang, W.; Pajkrt, D.; Wolthers, K. C.; Sridhar, A.; Simmini, S.
10.1101/2024.08.20.608742 — cell biology — Posted on 2024-08-20
1991 Integrated multi-model analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD
Gonzalez Acera, M.; Patankar, J. V.; Erkert, L.; Cineus, R.; Gamey Belmonte, R.; Leupold, T.; Bubeck, M.; Bao, L.-l.; Dinkel, M.; Wang, R.; Limberger, H.; Stolzer, I.; Gerlach, K.; Mascia, F.; Koop, K.; Plattner, C.; Strurm, G.; Weigmann, B.; Guenther, C.; Wirtz, S.; Hildner, K.; Kuehl, A. A.; Siegmund, B.; Atreya, R.; The IBDome Consortium, ; Hegazy, A. N.; Trajanoski, Z.; Neurath, M. F.; Becker, C.
10.1101/2024.08.14.607902 — systems biology — Posted on 2024-08-20
1992 Heparanase 2 regulates endothelial permeability and prevents from proteinuria via VEGFA and FGF signaling
Becker, Y.; Tkachuk, S.; Jörns, A.; Alwakaa, A.; Hegermann, J.; Heiko, S.; Kiyan, Y.; Haller, H.
10.1101/2024.08.14.608012 — physiology — Posted on 2024-08-20
1994 Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma
Yates, J.; Mathey-Andrews, C.; Park, J.; Garza, A.; Gagne, A.; Hoffman, S. E.; Bi, K.; Titchen, B.; Hennessey, C.; Remland, J.; Shannon, E. E.; Camp, S.; Balamurali, S.; Kiran Cavale, S.; Li, Z.; Kishore Raghawan, A.; Kraft, A.; Boland, G.; Aguirre, A. J.; Sethi, N.; Boeva, V.; Van Allen, E.
10.1101/2024.08.17.608386 — cancer biology — Posted on 2024-08-20
1995 The turbulent soundscape of intertidal oyster reefs
Volaric, M. P.; Stein, E. M.; Burtner, M.; Andrews, S. S.; Berg, P.; Reidenbach, M. A.
10.1101/2024.08.15.608049 — biophysics — Posted on 2024-08-20
1996 Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations
De La Forest Divonne, S.; Pouzadoux, J.; Romatif, O.; Montagnani, C.; Mitta, G.; Destoumieux-Garzon, D.; Gourbal, B.; Charriere, G. M.; Vignal, E.
10.1101/2024.07.19.604245 — immunology — Posted on 2024-08-20
2001 Long-term tracking of social structure in groups of rats
Nagy, M.; Davidson, J. D.; Vasarhelyi, G.; Abel, D.; Kubinyi, E.; El Hady, A.; Vicsek, T.
10.1101/2023.03.18.533183 — animal behavior and cognition — Posted on 2024-08-20
2004 Diverse Genotype-by-Weather Interactions in Switchgrass
MacQueen, A. H.; Zhang, L.; Smith, S. P.; Bonnette, J. E.; Boe, A. R.; Fay, P. A.; Fritschi, F. B.; Lowry, D. B.; Mitchell, R. B.; Rouquette, F. M.; Wu, Y.; Harpak, A.; Juenger, T. E.
10.1101/2021.08.19.456975 — genetics — Posted on 2024-08-20
2005 The molecular and cellular anatomy of a fetal programming defect: the impact of low protein diet on the developing kidney.
Short, K. M.; Tortelote, G. G.; Jones, L. K.; Diniz, F.; Edgington-Giordano, F.; Cullen-McEwen, L. A.; Schroeder, J.; Spencer, A.; Keniry, A.; Polo, J. M.; Bertram, J. F.; Blewitt, M. E.; Smyth, I. M.; El-dahr, S. S.
10.1101/2023.12.04.569988 — developmental biology — Posted on 2024-08-20
2007 Lipid discovery enabled by sequence statistics and machine learning
Christensen, P. M.; Martin, J.; Uppuluri, A.; Joyce, L. R.; Wei, Y.; Guan, Z.; Morcos, F.; Palmer, K.
10.1101/2023.10.12.562061 — microbiology — Posted on 2024-08-19
2017 Y chromosome linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues
Gorashi, R. M.; Baddour, T.; Chittle, S. J.; Velez, N. E. F.; Wenning, M. A.; Anseth, K. S.; Mestroni, L.; Pena, B.; Guo, P.; Aguado, B. A.
10.1101/2024.05.13.593760 — bioengineering — Posted on 2024-08-19
2018 MAASTY: A (dis)ordered copolymer for structural determination of human membrane proteins in native nanodiscs
pugh, c. f.; Praestegaard, K. F.; Feilen, L. P.; Borthwick, N. J.; Zivkovic, D.; de Lichtenberg, C.; Bolla, J. R.; Autzen, A. A. A.; Autzen, h. e.
10.1101/2024.08.19.608676 — biochemistry — Posted on 2024-08-19
2020 Expanding kinetoplastid genome annotation through protein structure comparison
Trinidad-Barnech, J. M.; Sotelo-Silveira, J.; Fernandez Do Porto, D.; Smircich, P.
10.1101/2024.08.07.607044 — genomics — Posted on 2024-08-19
2023 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Patel, S. P.; Munugala, C.; Bloom, J. S.; Kruglyak, L.
10.1101/2023.12.07.570640 — genetics — Posted on 2024-08-19
2025 Homoploid Hybrid Speciation in a Marine Pelagic Fish Megalaspis cordyla (Carangidae)
Muto, N.; Su, Y.-C.; Hata, H.; Nguyen, Q. V.; Vilasri, V.; Ghaffar, M. A.; Babaran, R. P.
10.1101/2024.08.17.608424 — evolutionary biology — Posted on 2024-08-19
2030 Bacterial cross-feeding can promote gene retention by lowering gene expression costs
Chuang, Y.-C.; Behringer, M. G.; Patton, G.; Bird, J. T.; Love, C. E.; Dalia, A. B.; McKinlay, J. B.
10.1101/2024.08.19.608702 — microbiology — Posted on 2024-08-19
2033 Hepatic iNKT cells facilitate colorectal cancer metastasis by inducing a fibrotic niche in the liver
Nater, M.; Brügger, M. D.; Cecconi, V.; Pereira, P.; Forni, G.; Köksal, H.; Dimakou, D.; Herbst, M.; Calvanese, A. L.; Lucchiari, G.; Schneider, C.; Valenta, T.; van den Broek, M.
10.1101/2024.08.19.608250 — immunology — Posted on 2024-08-19
2034 Functional identification of soluble uric acid as an endogenous inhibitor of CD38
Wen, S.; Arakawa, H.; Yokoyama, S.; Shirasaka, Y.; Higashida, H.; Tamai, I.
10.1101/2023.06.03.543541 — immunology — Posted on 2024-08-19
2035 Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation.
Carter-Cusack, D.; Huang, S.; Keshvari, S.; Patkar, O.; Sehgal, A.; Allavena, R.; Byrne, R.; Morgan, P.; Bush, S. J.; Summers, K. M.; Irvine, K. M.; Hume, D. A.
10.1101/2024.07.30.605701 — immunology — Posted on 2024-08-19
2038 Molecular Visualization of Neuronal TDP43 Pathology In Situ
Erwin, A. L.; Chang, M. L.; Fernandez, M. G.; Attili, D.; Russ, J. E.; Sutanto, R.; Pinarbasi, E. S.; Bekier, M.; Brant, T. S.; Hahn, T.; Dykstra, M.; Thomas, D.; Baldridge, R. D.; Tank, E. M. H.; Li, X.; Barmada, S. J.; Mosalaganti, S.
10.1101/2024.08.19.608477 — neuroscience — Posted on 2024-08-19
2040 Minimal exposures reveal visual processing priorities
Lanfranco, R. C.; Canales-Johnson, A.; Rabagliati, H.; Cleeremans, A.; Carmel, D.
10.1101/2021.10.06.462913 — neuroscience — Posted on 2024-08-19
2041 Stress Recovery Triggers Rapid Transcriptional Reprogramming and Activation of Immunity in Plants
Illouz-Eliaz, N.; Yu, J.; Swift, J.; Lande, K.; Jow, B.; Tuang, Z. K.; Lee, T.; Yaaran, A.; Castanon, R. G.; Nery, J. R.; Nobori, T.; Zait, Y.; Burdman, S.; Ecker, J. R.
10.1101/2023.02.27.530256 — plant biology — Posted on 2024-08-19
2043 Induction of Ferroptosis by an Amalgam of Extracellular Vesicles and Iron Oxide Nanoparticles Overcomes Cisplatin Resistance in Lung Cancer
Paramanantham, A.; Asfiya, R.; Manjunath, Y.; Xu, L.; McCully, G.; Das, S.; Yang, H.; Kaifi, J. T.; Srivastava, A.
10.1101/2024.08.19.608664 — cancer biology — Posted on 2024-08-19
2048 Dimerization GAS2 mediates microtubule and F-actin crosslinking
An, J.; Imasaki, T.; Narita, A.; Niwa, S.; Sasaki, R.; Makino, T.; Nitta, R.; Kikkawa, M.
10.1101/2024.08.19.608523 — biochemistry — Posted on 2024-08-19
2049 The ZIP8 A391T Crohn's disease-linked risk variant induces colonic metal ion dyshomeostasis, microbiome compositional shifts, and inflammation
Yang, J. C.; Zhao, M.; Chernikova, D.; Arias-Jayo, N.; Zhou, Y.; Situ, J.; Gutta, A.; Chang, C.; Liang, F.; Lagishetty, V.; Jacobs, J. P.
10.1101/2024.08.19.608695 — genomics — Posted on 2024-08-19
2054 RNA promotes mitochondrial import of F1-ATP synthase subunit alpha (ATP5A1)
Chatterjee, A.; Noble, M.; Sekaran, T.; Ravi, V.; Appel, D. F.; Schwarzl, T.; Rampelt, H.; Hentze, M. W.
10.1101/2024.08.19.608659 — cell biology — Posted on 2024-08-19
2055 Topical ABT-1 263 treatment reduces aged skin senescence and improves subsequent wound healing
Shvedova, M.; Thanapaul, R. J. R. S.; Ha, J.; Dhillon, J.; Shin, G. H.; Crouch, J.; Gower, A. C.; Gritli, S.; Roh, D. S.
10.1101/2024.08.19.608670 — cell biology — Posted on 2024-08-19
2057 Renal proximal tubules are sensitive to metabolic acidosis
Hennings, J. C.; Murthy, K. S.; Picard, N.; Cabrita, I.; Boehm, D.; Krause, M. E.; Shah, V.; Baraka-Vidot, J.; Khundadze, M.; Stauber, T.; Boeckenhauer, D.; Jentsch, T. J.; Bachmann, S.; Schermer, B.; Eladari, D.; Chambrey, R.; Huebner, C. A.
10.1101/2024.08.19.608649 — molecular biology — Posted on 2024-08-19
2059 Recent Bovine HPAI H5N1 Isolate is Highly Virulent for Mice, Rapidly Causing Acute Pulmonary and Neurologic Disease
Tipih, T.; Mariappan, V.; Yinda, K. C.; Meade-White, K.; Lewis, M.; Okumura, A.; McCarthy, N.; Clancy, C.; de Wit, E.; Munster, V. J.; Feldmann, H. U.; Rosenke, K.
10.1101/2024.08.19.608652 — microbiology — Posted on 2024-08-19
2060 Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion
Rodrigues, K. A.; Zhang, Y.; Aung, A.; Morgan, D. M.; Maiorino, L.; Yousefpour, P.; Gibson, G.; Ozorowski, G.; Gregory, J. R.; Amlashi, P.; Buckley, M.; Ward, A. B.; Schief, W. R.; Love, J. C.; Irvine, D. J.
10.1101/2024.08.19.608655 — immunology — Posted on 2024-08-19
2061 Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
Erkamp, N. A.; Farag, M.; Qiu, Y.; Qian, D.; Sneideris, T.; Wu, T.; Welsh, T. J.; Ausserwoger, H.; Krug, T. J.; Weitz, D.; Lew, M. D.; Knowles, T.; Pappu, R. V.
10.1101/2024.08.19.608662 — biophysics — Posted on 2024-08-19
2063 Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading
Parmenter, A. L.; Newham, E.; Sharma, A.; Disney, C. M.; Deyhle, H.; Bosi, F.; Terrill, N. J.; Bay, B. K.; Pitsillides, A. A.; Gupta, H. S.; Lee, P. D.
10.1101/2024.08.19.608559 — bioengineering — Posted on 2024-08-19
2064 Ex situ spawning, larval development, and settlement in the massive reef-building coral Porites lobata in Palau
Bennett, M.-J.; Grupstra, C.; Da-Anoy, J.; Andres, M. O.; Holstein, D.; Rossin, A.; Davies, S. W.; Meyer-Kaiser, K.
10.1101/2024.08.19.608627 — ecology — Posted on 2024-08-19
2065 The consequences of mismatched buffers in spectral cell sorting
Dapaah, R. A. S.; Ferrer Font, L.; Shi, X.; Hall, C.; Thompson, S.; Catharina Costa, L.; Mage, P. L.; Tyznik, A. J.; Lundsten, K.; Walker, R. V.
10.1101/2024.08.19.608560 — cell biology — Posted on 2024-08-19
2066 Blockade of rheumatoid arthritis synovial fluid-induced sensory neuron activation by JAK inhibitors
Li, Y.; Gray, E. H.; Ross, R.; Zebochin, I.; Lock, A.; Fedele, L.; Kamajaya, L. J.; Marrow, R. J.; Ryan, S.; Röderer, P.; Brüstle, O.; John, S.; Denk, F.; Taams, L. S.
10.1101/2024.08.19.608613 — immunology — Posted on 2024-08-19
2070 Dissecting the oncogenic mechanisms of POT1 cancer mutations through deep scanning mutagenesis
Martin, A.; Schabort, J.; Bartke-Croughan, R.; Tran, S.; Preetham, A.; Lu, R.; Ho, R.; Gao, J.; Jenkins, S.; Boyle, J.; Ghanim, G. E.; Jagota, M.; Song, Y. S.; Li, H.; Hockemeyer, D.
10.1101/2024.08.19.608636 — cancer biology — Posted on 2024-08-19
2075 CH-related Mutant ASXL1 Promotes Atherosclerosis in Mice via Dysregulated Innate Immunity
Sato, N.; Goyama, S.; Chang, Y.-H.; Fujino, T.; Denda, T.; Asada, S.; Shikata, S.; Liu, X.; Yonezawa, T.; Takeda, R.; Yamamoto, K.; Tanaka, Y.; Honda, H.; Ota, Y.; Shibata, T.; Sekiya, M.; Koide, S.; Lamagna, C.; Masuda, E.; Iwama, A.; Shimano, H.; Inoue, J.-i.; Miyake, K.; Kitamura, T.
10.1101/2024.08.18.608516 — cell biology — Posted on 2024-08-19
2077 Histone lactylation: a new epigenetic mark in the malaria parasite Plasmodium
Jabre, I.; Andoh, N. E.; Naldoni, J.; Gregory, W. F.; Yoon, C. E.; Cunnington, A. J.; Georgiadou, A.; Blagborough, A. M.; Merrick, C. J.
10.1101/2024.08.19.608576 — microbiology — Posted on 2024-08-19
2082 Acute inhibition of iron-sulfur cluster biosynthesis disrupts metabolic flexibility in mice
Possemato, R.; Molenaars, M.; Mir, H.; Schmidt, A. M.; Arivazhagan, L.; Rosselot, C.; Garcia-Ocana, A.; Park, C.; Zhan, D.; Alvarez, S.
10.1101/2024.08.19.608291 — physiology — Posted on 2024-08-19
2083 Tumor-associated macrophages confer resistance to chemotherapy (Trifluridine/Tipiracil) in digestive cancers by overexpressing Thymidine Phosphorylase
Malier, M.; Laverriere, M.-H.; Henry, M.; Yakoubi, M.; Bellaud, P.; Arellano, C.; Sebillot, A.; Thomas, F.; Josserand, V.; Girard, E.; Roth, G.; MILLET, A.
10.1101/2024.08.19.608621 — pathology — Posted on 2024-08-19
2084 Comparative effects of proton and photon irradiation on the molecular and cellular profiles of triple-negative breast cancer: the crucial impact of VEGFC on tumor microenvironment remodeling
Sarlak, S.; Marotte, D.; Morfoisse, F.; Pierantoni, A.; Sirera, J.; Tsai, M.-C.; Vidal, M.; Herault, J.; Garmy-Susini, B.; Doyen, J.; Luciano, F.; Pages, G.
10.1101/2024.08.19.608614 — cancer biology — Posted on 2024-08-19
2088 SegFinder: an automated tool for identifying RNA virus genome segments through co-occurrence in multiple sequenced samples
Liu, X.; Kong, J.; Shan, Y.; Yang, Z.; Miao, J.; Pan, Y.; Luo, T.; Shi, Z.; Wang, Y.; Gou, Q.; Yang, C.; Li, C.; Li, S.; Zhang, X.; Sun, Y.; Holmes, E. C.; Guo, D.; Shi, M.
10.1101/2024.08.19.608591 — bioinformatics — Posted on 2024-08-19
2093 Metabolic and Cellular Differences Between Sedentary and Active Individuals at Rest and During Exercise
San-Millan, I.; Martinez, J.; Sparagna, G.; D'Alessandro, A.; Stefanoni, D.; Nemkov, T.; Hill, J.
10.1101/2024.08.19.608601 — biochemistry — Posted on 2024-08-19
2094 Pumilio differentially binds to mRNA 3' UTR isoforms to regulate localization of synaptic proteins
Grzejda, D.; Hess, A.; Rezansoff, A.; Gorey, S.; Carrasco, J.; Alfonso-Gonzalez, C.; Tsagkris, S.; Neuhaus, L.; Ozbulut, H. C.; Voegtle, F.-N.; Vlachos, A.; Hilgers, V.
10.1101/2024.08.19.608606 — genomics — Posted on 2024-08-19
2098 Impactful feeding ecology of a predatory guild of oceanic jellies
Irvine, T.; Costello, J. H.; Gemmell, B.; Sutherland, K.; Colin, S.
10.1101/2024.08.19.608650 — ecology — Posted on 2024-08-19
2101 Influenza A virus within-host evolution and positive selection in a densely sampled household cohort over three seasons
Bendall, E. E.; Zhu, Y.; Fitzsimmons, W. J.; Rolfes, M.; Mellis, A.; Halasa, N.; Martin, E. T.; Grijalva, C. G.; Talbot, H. K.; Lauring, A. S.
10.1101/2024.08.15.608152 — microbiology — Posted on 2024-08-19
2105 Tim-3 promotes viral infection by suppressing USP25-TRAF3-IRF7 signaling pathway
Li, G.; Du, L.; Chen, J.; Du, C.; Chen, J.; Wang, C.; Bao, B.; LV, Z.; Xing, C.; Liang, M.; Wang, L.; Xie, S.; Li, Y.; Wang, Z.; Zhang, J.; Han, G.
10.1101/2024.08.19.608574 — immunology — Posted on 2024-08-19
2106 Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus 1 CNS infection
Ding, X.; Lei, X.; Klaestrup, I. H.; Jensen, S. R. N.; Nielsen, M. M.; Thorsen, K.; Romero-Ramos, M. R.; Luo, Y.; Lin, L.; Reinert, L. S.; Paludan, S. R.
10.1101/2024.08.19.608535 — immunology — Posted on 2024-08-19
2107 Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention
Sukhina, A.; Queriault, C.; Hall, E.; Rome, K.; Aggarwal, M.; Nunn, E.; Weiss, A.; Nguyen, J.; Bailis, W.
10.1101/2024.08.19.608575 — immunology — Posted on 2024-08-19
2113 Cerebellar encoding of prior knowledge of temporal statistics
Koppen, J.; Bayones, L.; Runge, M.; Klinkhamer, I.; Narain, D.
10.1101/2024.08.19.608550 — neuroscience — Posted on 2024-08-19
2114 Phased chromosome-level genome assembly provides insight into the origin of hexaploid sweetpotato
Wu, S.; Sun, H.; Hamilton, J. P.; Mollinari, M.; Gesteira, G. D. S.; Kitavi, M.; Yan, M.; Wang, H.; Yang, J.; Yencho, G. C.; Buell, C. R.; Fei, Z.
10.1101/2024.08.17.608395 — plant biology — Posted on 2024-08-19
2116 Developmental variability in cotton fiber cell wall properties linked to important agronomic traits
Wilson, M. C.; Howell, A. H.; Sood, A.; Lee, Y.; Yang, P.; Rani, H.; Yu, E.; Mallery, E. L.; Swaminathan, S.; Grover, C. E.; Wendel, J. F.; Zabotina, O. A.; Xie, J.; Davis, C. S.; Szymanski, D.
10.1101/2024.08.19.607249 — plant biology — Posted on 2024-08-19
2118 Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe
stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.
10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-08-19
2120 Chaotic dynamics for homeostatic hematopoiesis
Jia, D.; Cavazos, E. S.; West, T.; Liang, S.-H.; Costa, R.; Salomon, M. C.; Huang, A.; Trinchieri, G.; Lionakis, M.; Mukherjee, R.; Altan-Bonnet, G.
10.1101/2024.08.16.608266 — immunology — Posted on 2024-08-19
2133 Intraperitoneal programming of tailored CAR macrophages via mRNA-LNP to boost cancer immunotherapy
Gu, K.; Liang, T.; Hu, L.; Zhao, Y.; Ying, W.; Zhang, M.; Chen, Y.; Liang, B.; Lin, X.; Zhang, Y.; Wu, H.; Wang, M.; Zhu, Y.; Wang, W.; Zhang, Y.; Zuo, C.; Du, Z.; Zhang, P.; Song, J.; Liu, X.; Xie, S.; Tan, W.
10.1101/2024.07.30.605730 — bioengineering — Posted on 2024-08-19
2135 The first assembled chromosome-level genome of an individual from Karnataka, India
mhatre, A.; Chindarkar, Y.; Ganesh, A.; Thakare, A.; Mishra, P.; Ravindran, F.; Sharma, A.; Srinivasan, S.; Choudhary, B.
10.1101/2024.08.18.608448 — genomics — Posted on 2024-08-19
2136 Thoracic Aortic 3-Dimensional Geometry: Effects of Aging and Genetic Determinants
Beeche, C.; Dib, M.-J.; Zhao, B.; Azzo, J.-D.; Maynard, H.; Duda, J.; Gee, J.; Salman, O.; Witschey, W.; Chirinos, J.
10.1101/2024.05.09.593413 — genomics — Posted on 2024-08-19
2138 Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment
Urbancokova, A.; Hornofova, T.; Novak, J.; Salajkova, S. A.; Stemberkova Hubackova, S.; Uvizl, A.; Buchtova, T.; Mistrik, M.; Mac Stay, B.; Hodny, Z.; Bartek, J.; Vasicova, P.
10.1101/2023.08.05.552131 — cell biology — Posted on 2024-08-19
2139 LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARgamma Signaling
Xie, X.; Gao, M.; Zhao, W.; Li, C.; Zhang, W.; Yang, J.; Zhang, Y.; Chen, E.; Guo, Y.; Guo, Z.; Zhang, M.; Ngowi, E. E.; Wang, H.; Wang, X.; Zhu, Y.; Wang, Y.; Li, X.; Yao, H.; Yan, L.; Fang, F.; Li, M.; Qiao, A.; Liu, X.
10.1101/2024.03.22.586335 — molecular biology — Posted on 2024-08-19
2142 The glycolytic reaction PGAM unexpectedly restrains Th17 pathogenicity and Th17-dependent autoimmunity
Wang, C.; Wagner, A.; Fessler, J.; DeTomaso, D.; Zaghouani, S.; Zhou, Y.; Pierce, K.; Sobel, R. A.; Clish, C.; Yosef, N.; Kuchroo, V. K.
10.1101/2024.08.18.607992 — immunology — Posted on 2024-08-19
2143 Neural Mechanisms of Feedback Processing and Behavioral Adaptation during Neurofeedback Training
Pamplona, G. S. P.; Zweerings, J.; Lor, C. S.; deErney, L.; Roecher, E.; Taebi, A.; Hellrung, L.; Amano, K.; Scheinost, D.; Krause, F.; Rosenberg, M. D.; Ionta, S.; Brem, S.; Hermans, E.; Mathiak, K.; Scharnowski, F.
10.1101/2024.08.19.608543 — neuroscience — Posted on 2024-08-19
2145 Interdependence of plasma membrane nanoscale dynamics of a kinase and its cognate substrate underlies Arabidopsis response to viral infection
Jolivet, M.-D.; Deroubaix, A.-F.; Boudsocq, M.; Abel, N. B.; Rocher, M.; Robbe, T.; Wattelet, V.; Huard, J.; Lefebvre, D.; Lu, Y.-J.; Day, B.; Saias, G.; Ahmed, J.; Cotelle, V.; Giovinazzo, N.; Gallois, J.-L.; Yamaji, Y.; German-Retana, S.; Gronnier, J.; Ott, T.; Mongrand, S.; Germain, V.
10.1101/2023.07.31.551174 — plant biology — Posted on 2024-08-19
2146 Identifiability of heterogeneous phenotype adaptation from low-cell-count experiments and a stochastic model
Browning, A. P.; Crossley, R. M.; Villa, C.; Maini, P. K.; Jenner, A. L.; Cassidy, T.; Hamis, S.
10.1101/2024.08.19.608540 — cancer biology — Posted on 2024-08-19
2153 Mycn regulates vascular development through PI3K signaling pathway in zebrafish
Zhao, G.-Q.; Cheng, T.; Wang, P.-Y.; Mo, J.; Yu, F.; Dong, Y.; Li, Y.-F.; Feng, Y.; Xu, P.-F.; Shu, L.-P.
10.1101/2024.08.19.608563 — developmental biology — Posted on 2024-08-19
2154 Haploid Asexual Blastocyst Fitness Varies Across Mouse Strains Related to Efficiency of Exit From Totipotency
Crasta, D. N.; Lee, S. W.; Fredrickson, J.; Thejo, T.; Adiga, S. K.; Zhao, Y.; Kalthur, G.; Kannan, N.
10.1101/2024.08.19.608531 — developmental biology — Posted on 2024-08-19
2155 The exocyst complex controls multiple events in the pathway of regulated exocytosis.
Freire, S. S.; Perez-Pandolfo, S.; Fresco, S. M.; Valinoti, J.; Sorianello, E.; Wappner, P.; Melani, M.
10.1101/2023.08.31.555734 — cell biology — Posted on 2024-08-19
2156 Exploring 3-Aminobenzoic Acid as a Therapeutic Dietary Component for Enhancing Intestinal Barrier Integrity in Ulcerative Colitis
Tanaka, M.; Toyonaga, T.; Nakagawa, F.; Iwamoto, T.; Komatsu, A.; Sumiyoshi, N.; Shibuya, N.; Minemura, A.; Ariyoshi, T.; Matsumoto, A.; Oka, K.; Shimoda, M.; Saruta, M.
10.1101/2024.08.18.608525 — molecular biology — Posted on 2024-08-19
2157 Crystal structure and activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease revealed new allosteric sites for antiviral therapies
Choudhary, S.; Nehul, S.; Nagaraj, S. K.; Narayan, R.; Verma, S.; Sharma, S.; Kumari, A.; Rani, R.; Saha, A.; Sircar, D.; Tripathi, S.; Sharma, G. K.; Kumar, P.; Tomar, S.
10.1101/2022.11.11.516107 — molecular biology — Posted on 2024-08-19
2161 Early antiviral CD4 and CD8 T cell responses and antibodies are associated with upper respiratory tract clearance of SARS-CoV-2
Ramirez, S. I.; Lopez, P. G.; Faraji, F.; Parikh, U. M.; Heaps, A.; Ritz, J.; Moser, C.; Eron, J. J.; Wohl, D. A.; Currier, J. S.; Daar, E. S.; Greninger, A. L.; Klekotka, P.; Grifoni, A.; Weiskopf, D.; Sette, A.; Peters, B.; Hughes, M. D.; Chew, K. W.; Smith, D. M.; Crotty, S.; ACTIV-2/A5401 Study Team,
10.1101/2023.10.25.564014 — immunology — Posted on 2024-08-19
2162 Microbial metabolite-guided CAR T cell engineering enhances anti-tumor immunity via epigenetic-metabolic crosstalk
Staudt, S.; Nikolka, F.; Perl, M.; Franz, J.; Leblay, N.; Yuan, X.-K.; Warmuth, L.; Fantes, M. A.; Skorpskaite, A.; San Mrtin-Uriz, P.; Rodriguez-Madoz, J. R.; Ziegler-Martin, K.; Adil-Gholam, N.; Benz, P.; Tran Huu, P.; Stein-Thoeringer, C.; Schmitt, M.; Kleigrewe, K.; Freitag, F.; Riester, Z.; Weber, J.; Mangold, K.; Einsele, H.; Prosper, F.; Ellmeier, W.; Busch, D.; Visekruna, A.; Hiller, K.; van den Brink, M.; Pausch, P.; Neri, P.; Hudecek, M.; Poeck, H.; Luu, M.
10.1101/2024.08.19.608538 — immunology — Posted on 2024-08-19
2163 Deconstructing CTL-mediated autoimmunity through weak TCR-cross-reactivity towards highly abundant self-antigen
Plach, A.; Muhlgrabner, V.; Rodak, A.; Platzer, R.; Doel Perez, I.; Fellinger, P.; Peters, T.; Winhofer, Y.; Madritsch, C.; Schrangl, L.; Stockinger, H.; Dupre, L.; Busch, D. B.; Schober, K.; Gohring, J.; Huppa, J. B.
10.1101/2024.08.17.608371 — immunology — Posted on 2024-08-19
2165 Attention and working memory investigated through the P300 component in children practicing Karate at different stages of biological maturation
Nicoliche, E.; Vasconcelos, A.; machado, m.; Tanaka, G.; Vicente, R.; Marques, A.; Costa, E.; Gongora, M.; Di Giacomo, J.; Nobre, M.; Teixeira, S.; Bastos, V.; Cagy, M.; Fernandes, I.; Machado, C.; Ribeiro, P.; Gupta, D.; Velasques, B.; Budde, H.
10.1101/2024.08.18.608511 — neuroscience — Posted on 2024-08-19
2168 GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
Sivadasan Bindu, D.; Savage, J. T.; Brose, N.; Bradley, L.; Dimond, K.; Tan, C. X.; Eroglu, C.
10.1101/2023.01.17.524433 — neuroscience — Posted on 2024-08-19
2169 Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism
Lin, S.; Gade, A. R.; Wang, H.-G.; Niemeyer, J. E.; Galante, A.; DiStefano, I.; Towers, P.; Nunez, J.; Matsui, M.; Schwartz, T. H.; Rajadhyaksha, A.; Pitt, G. S.
10.1101/2024.04.18.590019 — neuroscience — Posted on 2024-08-19
2173 Muscle Fibroblasts and Stem Cells Stimulate Motor Neurons in An Age and Exercise-Dependent Manner
Soendenbroe, C.; Schjerling, P.; Bechshoeft, C. J. L.; Svensson, R. B.; Schaeffer, L.; Kjaer, M.; Chazaud, B.; Jacquier, A.; Mackey, A. L.
10.1101/2024.08.19.608387 — physiology — Posted on 2024-08-19
2177 DNA polymerase kappa stabilized by PTBP2 interacts with MRE11 and promotes genomic instability in leukemia cells
Lama, S.; Barik, B.; I.S., S.; Sarkar, T.; Chanda, S.; Behera, M.; Behera, S. P.; Biswas, S.; Mohapatra, S.; Biswas, G.; Chakraborty, S.
10.1101/2024.08.18.608437 — cancer biology — Posted on 2024-08-19
2178 Protection of the Telomeric Junction by the Shelterin Complex
Shiekh, S.; Feldt, D.; Jack, A.; Kodikara, S.; Alfehaid, J.; Pasha, S.; Yildiz, A.; Balci, H.
10.1101/2024.08.18.608453 — biophysics — Posted on 2024-08-19
2183 Is there a right place? The effect of oviposition site selection on offspring survival in a glassfrog
Angiolani Larrea, F. N.; Valencia-Aguilar, A.; Garrido-Priego, M.; Culebras, J.; Peignier, M.; Jindiachi, L.; Tinajero-Romero, J. G.; Guayasamin, J. M.; Ringler, E.
10.1101/2024.08.18.608513 — animal behavior and cognition — Posted on 2024-08-19
2185 Trade-offs beget trade-offs: Causal analysis of mammalian population dynamics
Bergman, J.; Pedersen, R. O.; Lundgren, E. J.; Trepel, J.; Pearce, E. A.; Czyzewski, S.; Tietje, M.; Lemoine, R. T.; Coll Macia, M.; Schierup, M. H.; Svenning, J.-C.
10.1101/2024.08.16.608243 — evolutionary biology — Posted on 2024-08-19
2188 Connectivity of the neuronal network for contextual fear memory is disrupted in a mouse model of third-trimester binge-like ethanol exposure
Morningstar, M. D.; Lopez, K. M.; Mayfield, S. S.; Almeida-Mancero, R. N.; Marquez, J.; Flores, A. M.; Hafer, B. R.; Estrada, E.; Holtzman, G. A.; Goranson, E. V.; Reid, N. M.; Aldrich, A. R.; Ghatalia, D. V.; Patel, J. R.; Padilla, C. M.; Chavez, G. J.; Roman, J. K.; Bhakta, P. A.; Valenzuela, C. F.; Linsenbardt, D. D.
10.1101/2024.08.16.608336 — neuroscience — Posted on 2024-08-19
2190 ClearScope: a fully integrated light sheet theta microscope for sub-cellular resolution imaging without lateral size constraints
Fay, M. G.; Lang, P. J.; Denu, D. S.; O'Connor, N. J.; Haydock, B. W.; Blaisdell, J. O.; Roussel, N.; Wilson, A. L.; Aronson, S. R.; Angstman, P. J.; Gong, C.; Butola, T.; Devinsky, O.; Basu, J.; Tomer, R.; Glaser, J. R.
10.1101/2024.08.15.608141 — neuroscience — Posted on 2024-08-19
2191 Engagement in moderate-intensity physical activity supports overnight emotional memory retention in older adults
Chappel-Farley, M. G.; Berisha, D. E.; Dave, A.; Sanders, R. M.; Kline, C. E.; Janecek, J. C.; Sattari, N.; Lui, K. K.; Chen, I. Y.; Neikrug, A. B.; Benca, R. M.; Yassa, M. A.; Mander, B. A.
10.1101/2024.08.16.608272 — neuroscience — Posted on 2024-08-19
2194 Low hemoglobin causes hematoma expansion and poor intracerebral hemorrhage outcomes
Cottarelli, A.; Momoon, R.; Ji, R.; Mao, E.; Boehme, A. K.; Kumar, A.; Song, S.; Allegra, V.; Sharma, S. V.; Konofagou, E.; Spektor, V.; Guo, J.; Connolly, E. S.; Sekar, P.; Woo, D.; Roh, D. J.
10.1101/2024.08.15.608155 — pathology — Posted on 2024-08-19
2197 SUV39H1 Preserves Cancer Stem Cell Chromatin State and Properties in Glioblastoma
Li, C.; Xie, Q.; Ghosh, S.; Cao, B.; Du, Y.; Vo, G. V.; Huang, T. Y.; Spruck, C.; Wang, Y. A.; Nephew, K. P.; Shen, J.
10.1101/2024.08.15.607856 — cancer biology — Posted on 2024-08-19
2199 Dissecting contributions of pulmonary arterial remodeling to right ventricular afterload in pulmonary hypertension
Neelakantan, S.; Mendiola, E. A.; Vang, A.; Myers, K. J.; Zhang, P.; Choudhary, G.; Avazmohammadi, R.
10.1101/2024.08.18.608471 — bioengineering — Posted on 2024-08-19
2200 Dimerization GAS2 mediates microtubule and F-actin crosslinking
Jiancheng, A.; Imasaki, T.; Narita, A.; Niwa, S.; Sasaki, R.; Makino, T.; Nitta, R.; Kikkawa, M.
10.1101/2024.08.19.608523 — biochemistry — Posted on 2024-08-19
2204 High-speed whole-genome sequencing of a Whippet: Rapid chromosome-level assembly and annotation of an extremely fast dog's genome
Nebenfuehr, M.; Prochotta, D.; Ben Hamadou, A.; Janke, A.; Gerheim, C.; Betz, C.; Greve, C.; Bolz, H. J.
10.1101/2024.08.16.608262 — genomics — Posted on 2024-08-19
2206 Transgressive Hybrids as Hopeful Holobionts
Camper, B. T.; Kanes, A. S.; Laughlin, Z. T.; Manuel, R. T.; Bewick, S. A.
10.1101/2024.08.17.607925 — evolutionary biology — Posted on 2024-08-19
2207 Variations in flight strategy of small migratory birds crossing major ecological barriers
Dufour, P.; Nussbaumer, R.; Bocher, P.; Briedis, M.; Coulomb, Y.; Delacroix, R.; Dagonet, T.; de Franceschi, C.; de Grissac, S.; Jeannin, B.; Monchatre, R.; Rey, F.; Tillo, S.; Champagnon, J.; Duriez, O.; Jiguet, F.
10.1101/2024.08.18.608464 — ecology — Posted on 2024-08-19
2208 Species-specific interactions with apex carnivores yield unique benefits and burdens for mesocarnivores
Binder, W.; Rabe, J.; Lowe, Z.; Scott, G.; Lacey, C.; King, E.; Stahler, D. R.; Chakrabarti, S.
10.1101/2024.08.17.608414 — ecology — Posted on 2024-08-19
2210 ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing.
Pandey, A.; Cousin, H.; Kumar, S.; Taylor, L.; Chander, A.; Coppenrath, K.; Shaidani, N.-I.; Horb, M.; Alfandari, D.
10.1101/2024.08.18.608474 — developmental biology — Posted on 2024-08-19
2212 Three-dimension transcriptomics maps of whole mouse embryo during organogenesis
Cheng, M.; Zheng, H.; Fang, Q.; Bai, Y.; Liu, C.; Pan, H.; Zhang, Z.; Lu, Q.; Shi, C.; Xia, T.; Jing, Z.; Liu, H.; Feng, N.; Fu, G.; Li, Y.; Feng, J.; Li, Z.; Wang, J.; Chen, Y.; Wang, L.; Deng, Z.; Li, M.; Liu, L.; Chen, A.; Xu, X.
10.1101/2024.08.17.608366 — developmental biology — Posted on 2024-08-19
2213 C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
Tanaka, T.; Sasaki, N.; Krisnanda, A.; Amin, H. Z.; Ito, K.; Horibe, S.; Matsuo, K.; Hirata, K.-i.; Nakayama, T.; Rikitake, Y.
10.1101/2024.08.16.608245 — immunology — Posted on 2024-08-19
2214 An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans
Kakade, P.; Burgueno, J. F.; Sircaik, S.; Ponde, N.; Li, J.; Ene, I. V.; Kim, J.; Liang, S.-H.; Yunker, R.; Akiba, Y.; Vaishnava, S.; Kaunitz, J. D.; Way, S. S.; Koh, A. Y.; Gaffen, S.; Abreu, M. T.; Bennett, R. J.
10.1101/2024.08.16.608271 — immunology — Posted on 2024-08-19
2215 Tissue determinants of the human T cell receptor repertoire.
Sureshchandra, S.; Henderson, J.; Levendosky, E.; Bhattacharyya, S.; Kastenschmidt, J. M.; Sorn, A. M.; Mitul, M. T.; Benchorin, A.; Batucal, K.; Daugherty, A.; Murphy, S. J.; Thakur, C.; Trask, D.; Ahuja, G.; Moisan, A.; Tiffeau-Mayer, A.; Saligrama, N.; Wagar, L. E.
10.1101/2024.08.17.608295 — immunology — Posted on 2024-08-19
2216 Macrophage WDFY3, a protector against autoimmunity
Wu, X.; Wang, Z.; Croce, K. R.; Li, F.; Cui, J.; D'Agati, V. C.; Soni, R.; Khalid, S.; Saleheen, D.; Tabas, I.; Yamamoto, A.; Zhang, H.
10.1101/2024.08.17.608411 — immunology — Posted on 2024-08-19
2217 A virtual clinical trial of psychedelics to treat patients with disorders of consciousness
Alnagger, N. L. N.; Cardone, P.; Martial, C.; Sanz Perl, Y.; Mindlin, I.; Sitt, J. D.; Roseman, L.; Carhart-Harris, R.; Nutt, D.; Mallaroni, P.; Mason, N. L.; Ramaekers, J. G.; Bonhomme, V.; Laureys, S.; Deco, G.; Gosseries, O.; Nunez, P.; Annen, J.
10.1101/2024.08.16.608251 — neuroscience — Posted on 2024-08-19
2218 Benchmarking macaque gene expression for horizontal and vertical translation
Luppi, A. I.; Liu, Z.-Q. I.; Hansen, J. Y.; Cofre, R.; Kuzmin, E. G.; Froudist-Walsh, S.; Palomero-Gallagher, N.; Misic, B.
10.1101/2024.08.18.608440 — neuroscience — Posted on 2024-08-19
2221 Platelet-derived LPA16:0 inhibits adult neurogenesis and stress resilience in anxiety disorder
Larrieu, T.; Carron, C.; Grieco, F.; Weber, C.; Ginggen, K.; Delacretaz, A.; Gallart-Ayala, H.; Tsuda, M.; Cameron, H.; Eap, C.; Ivanisevic, J.; Magistretti, P.; Telley, L.; Dayer, A.; Piguet, C.; Toni, N.
10.1101/2024.08.18.608479 — neuroscience — Posted on 2024-08-19
2222 Biological sex and BMI influence the longitudinal evolution of adolescent and young adult MRI-visible perivascular spaces
Yamamoto, E. A.; Koike, S.; Wong, C.; Dennis, L.; Luther, M. N.; Scatena, A.; Khambadkone, S.; Iliff, J.; Lim, M. M.; Levendovszky, S. R.; Elliott, J.; Barisano, G.; Muller-Oehring, E.; Morales, A. M.; Baker, F.; Nagel, B.; Piantino, J.
10.1101/2024.08.17.608337 — neuroscience — Posted on 2024-08-19
2223 Prefrontal Excitation/ Inhibition Balance Supports Adolescent Enhancements in Circuit Signal to Noise Ratio
McKeon, S. D.; Perica, M. I.; Calabro, F. J.; Foran, W.; Hetherington, H.; Moon, C.-H.; Luna, B.
10.1101/2024.08.15.608100 — neuroscience — Posted on 2024-08-19
2225 An Infralimbic Cortex Neuronal Ensemble Encoded During Learning Attenuates Fear Generalization Expression
Subramanian, R.; Bauman, A.; Carpenter, O.; Cho, C.; Coste, G.; Dam, A.; Ehnstrom, S.; Fitzgerald, N.; Jenkins, A.; Koolpe, H.; Lui, R.; Paserman, T.; Petersen, D.; Chavez, D. S.; Rozental, S.; Thompson, H.; Tsukuda, T.; Zweig, S.; Gall, M.; Zupan, B.; Bergstrom, H.
10.1101/2024.08.18.608308 — neuroscience — Posted on 2024-08-19
2226 Ultra-low-field brain MRI morphometry: test-retest reliability and correspondence to high-field MRI
Vasa, F.; Bennallick, C.; Bourke, N. J.; Padormo, F.; Baljer, L.; Briski, U.; Cawley, P.; Arichi, T.; Wood, T. C.; Lythgoe, D. J.; Dell'Acqua, F.; Booth, T. C.; Venkataraman, A. V.; Ljungberg, E.; Deoni, S. C. L.; Moran, R. J.; Leech, R.; Williams, S. C. R.
10.1101/2024.08.14.607942 — neuroscience — Posted on 2024-08-19
2229 BundleAGE: Predicting White Matter Age using Along-Tract Microstructural Profiles from Diffusion MRI
Feng, Y.; Villalon-Reina, J. E.; Nir, T. M.; Chandio, B. Q.; Jahanshad, N.; Thompson, P. M.
10.1101/2024.08.16.608347 — neuroscience — Posted on 2024-08-19
2232 Deep Learning and 3D Imaging Reveal Whole-Body Alterations in Obesity
Kaltenecker, D.; Horvath, I.; Al-Maskari, R.; Kolabas, Z. I.; Chen, Y.; Hoeher, L.; Todorov, M.; Kapoor, S.; Ali, M.; Kofler, F.; Morigny, P.; Geppert, J.; Jeridi, D.; Cigankova, C.; Kolenic, V. M.; Gur, N.; Pan, C.; Piraud, M.; Rueckert, D.; Rohm, M.; Hellal, F.; Elsner, M.; Bhatia, H. S.; Menze, B. H.; Herzig, S.; Paetzold, J. C.; Diaz, M. B.; Erturk, A.
10.1101/2024.08.18.608300 — systems biology — Posted on 2024-08-19
2235 Flower bud cooling protects pollen development and improves fertility during heatwaves
Jansen, M. J.; Jansma, S. Y.; Kuipers, K. M.; Vriezen, W. H.; Millenaar, F. F.; Montoro, T.; de Kovel, C. G. F.; van Eeuwijk, F. A.; Visser, E. J. W.; Rieu, I.
10.1101/2024.08.18.608441 — plant biology — Posted on 2024-08-19
2237 Intercellular compartmentation of trehalose 6-phosphate metabolism in Setaria viridis leaves
Tonetti, T.; Rojas, B. E.; Lucero, L. E.; Feil, R.; Calace, P.; Saigo, M.; Arrivault, S.; Stitt, M.; Lunn, J. E.; Figueroa, C. M.
10.1101/2024.08.16.608293 — plant biology — Posted on 2024-08-19
2238 Endothelial β1 Integrins are Necessary for Microvascular Function and Glucose Uptake
Winn, N. C.; Roby, D. A.; McClatchey, P. M.; Williams, I. M.; Bracy, D. P.; Bedenbaugh, M. N.; Lantier, L.; Plosa, E. J.; Pozzi, A.; Zent, R.; Wasserman, D. H.
10.1101/2024.08.18.607045 — physiology — Posted on 2024-08-19
2239 The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21
Xu, S.; Liu, Z.; Tian, T.; Zhao, W.; Wang, Z.; Liu, M.; Xu, M.; Zhang, F.; Zhang, Z.; Chen, M.; Yin, Y.; Su, M.; Pan, W.; Liu, S.; Li, M.-d.; Little, P.; Danielle Kamato, D.; Zhang, S.-y.; Wang, D.; Offermanns, S.; Speakman, J.; Weng, J.
10.1101/2024.08.18.608423 — pharmacology and toxicology — Posted on 2024-08-19
2241 Dysregulated Cholesterol Metabolism with Anomalous PI3K/Akt/mTOR pathway Predicts Poor Carboplatin Response in High Grade Serous Ovarian Cancer
MAHAPATRA, E.; SAHA, A.; NAG, N.; GOPE, A.; THAKUR, D.; VERNEKAR, M.; CHAKRABARTI, J.; BASU, M.; PAL, A.; SENGUPTA, S.; MUKHERJEE, S.
10.1101/2024.08.17.608375 — cancer biology — Posted on 2024-08-19
2243 Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma
Yates, J.; Mathey-Andrews, C.; Park, J.; Garza, A.; Gagne, A.; Hoffman, S. E.; Bi, K.; Titchen, B.; Hennessey, C.; Remland, J.; Shannon, E. E.; Camp, S.; Balamurali, S.; Kiran Cavale, S.; Li, Z.; Kishore Raghawan, A.; Kraft, A.; Boland, G.; Aguirre, A. J.; Sethi, N.; Boeva, V.; Van Allen, E.
10.1101/2024.08.17.608386 — cancer biology — Posted on 2024-08-19
2247 Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs
Shuttleworth, J. G.; Lei, C. L.; Windley, M. J.; Hill, A. P.; Preston, S. P.; Mirams, G. R.
10.1101/2024.08.16.608289 — biophysics — Posted on 2024-08-19
2248 Low-cost and highly efficient generation of near-complete bacterial pathogen genomes by TELL-Seq
Wu, Z.; Zhang, T.; Li, S.; Shen, L.; Yang, Z.; Yang, Y.; Chen, X.; Li, B.; Zhou, S.; Zhou, X.; Wu, B.; Jiang, J.; Li, X.
10.1101/2024.08.17.608388 — bioinformatics — Posted on 2024-08-19
2249 DeepSomatic: Accurate somatic small variant discovery for multiple sequencing technologies
Park, J.; Cook, D. E.; Chang, P.-C.; Kolesnikov, A.; Brambrink, L.; Mier, J. C.; Gardner, J.; McNulty, B.; Sacco, S.; Keskus, A.; Bryant, A.; Ahmad, T.; Shetty, J.; Zhao, Y.; Tran, B.; Narzisi, G.; Helland, A.; Yoo, B.; Pushel, I.; Lansdon, L. A.; Bi, C.; Walter, A.; Gibson, M.; Pastinen, T.; Farooqi, M. S.; Robine, N.; Miga, K. H.; Carroll, A.; Kolmogorov, M.; Paten, B.; Shafin, K.
10.1101/2024.08.16.608331 — bioinformatics — Posted on 2024-08-19
2252 Spatial Immunophenotyping from Whole-Slide Multiplexed Tissue Imaging Using Convolutional Neural Networks
Yosofvand, M.; Edmiston, S. N.; Smithy, J. W.; Peng, X.; Kostrzewa, C. E.; Lin, B.; Ehrich, F.; Reiner, A.; Miedema, J.; Moy, A. P.; Orlow, I.; Postow, M. A.; Panageas, K.; Seshan, V. E.; Callahan, M. K.; Thomas, N. E.; Shen, R.
10.1101/2024.08.16.608247 — bioinformatics — Posted on 2024-08-19
2258 Function-first discovery of high affinity monoclonal antibodies using Nanovial-based plasma B cell screening
Challa, D.; de Rutte, J.; Konu, C.; Udani, S.; Liang, J.; Krohl, P. J.; Rondon, R.; Bondensgaard, K.; Di Carlo, D.; Watkins-Yoon, J.
10.1101/2024.08.15.608174 — bioengineering — Posted on 2024-08-19
2259 Rapid in situ forming PEG hydrogels for mucosal drug delivery
Yeruva, T.; Morris, R. J.; Zhao, L.; Kofinas, P.; Duncan, G. A.
10.1101/2024.08.16.608319 — bioengineering — Posted on 2024-08-19
2260 A Continuous, Low-Flow, and Multiplexing Pumping System for Microfluidics Applications
Walp, K. A.; Patel, Y. H.; Alsadoun, W.; Gordon, H. L.; Rastaghi, H.; M. D. Oliveira, S.
10.1101/2024.08.16.608339 — bioengineering — Posted on 2024-08-19
2261 Enhanced Piezoelectric Performance of PVDF-TrFE Nanofibers through Annealing for Tissue Engineering Applications
Krutko, M.; Poling, H. M.; Bryan, A.; Sharma, M.; Singh, A.; Al. Reza, H.; Wikenheiser-brokamp, K.; Takebe, T.; Helmrath, M.; Harris, G. M.; Esfandiari, L.
10.1101/2024.08.16.608345 — bioengineering — Posted on 2024-08-19
2263 Dynamic Hydrogel Crosslink Strength Controls Yielding Characteristics and Cell Viability During Injection
Eckman, N.; Grosskopf, A. K.; Jiang, G.; Kamani, K.; Huang, M.; Schmittlein, B.; Heilshorn, S. C.; Rogers, S.; Appel, E.
10.1101/2024.08.16.608324 — bioengineering — Posted on 2024-08-19
2266 Extending the IICR to multiple genomes and identification of limitations of some demographic inferential methods
Chikhi, L.; Rodriguez, W.; Paris, C.; Ha-Shan, M.; Jouniaux, A.; Arredondo, A.; Nous, C.; Grusea, S.; Corujo, J.; Lourenco, I.; Boitard, S.; Mazet, O.
10.1101/2024.08.16.608273 — evolutionary biology — Posted on 2024-08-19
2268 Homoploid Hybrid Speciation in a Marine Pelagic Fish Megalaspis cordyla (Carangidae)
Muto, N.; Su, Y.-C.; Hata, H.; Nguyen, Q. V.; Ghaffar, M. A.; Vilasri, V.; Babaran, R. P.
10.1101/2024.08.17.608424 — evolutionary biology — Posted on 2024-08-19
2269 Sex differences and behaviour in the pace-of-life of rodents
Hughes, B.; Mastromonaco, G.; Bowman, J.; Schulte-Hostedde, A.
10.1101/2024.08.15.608175 — ecology — Posted on 2024-08-19
2271 Benchmarking for the automated detection and classification of southern yellow-cheeked crested gibbon calls from passive acoustic monitoring data
Clink, D. J.; Cross-Jaya, H.; Kim, J.; Ahmad, A. H.; Hong, M.; Sala, R.; Birot, H.; Agger, C.; Vu, T. T.; Thi, H. N.; Chi, T. N.; Klinck, H.
10.1101/2024.08.17.608420 — ecology — Posted on 2024-08-19
2272 FSP1 stem/progenitor cells are essential for TMJ growth and homeostasis
Tuwatnawanit, T.; Wessman, W.; Belisova, D.; Sumbalova, Z.; Tucker, A. S.; Anthwal, N.
10.1101/2024.08.16.608236 — developmental biology — Posted on 2024-08-19
2274 Oncolytic vaccinia virus as a precision cancer vaccine platform
Komant, S. J.; Wang, J. L.; Favis, N.; Alex, C.; Evans, D. H.; Noyce, R. S.; Baldwin, T. A.
10.1101/2024.08.16.608170 — immunology — Posted on 2024-08-19
2276 Exercise-stimulated Resolvin Biosynthesis in Adipose Tissue is Abrogated by High Fat Diet-induced Adrenergic Deficiency
Pena Calderin, E. H.; Zheng, J.-J.; Boyd, N. L.; Lynch, W.; Sansbury, B. E.; Spite, M.; Hill, B. G.; Hellmann, J.
10.1101/2024.08.14.608014 — immunology — Posted on 2024-08-19
2281 Sapphire-Based Optrode for Low Noise Neural Recording and Optogenetic Manipulation
Xu, Y.; Li, B.-Z.; Huang, X.; Liu, Y.; Liang, Z.; Yang, X.; Lin, L.; Wang, L.; Xia, Y.; Ridenour, M.; Huang, Y.; Zhen, Y.; Klug, A.; Pun, S. H.; Lei, T. C.; Zhang, B.
10.1101/2024.08.15.608194 — neuroscience — Posted on 2024-08-19
2282 Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage
Geraghty, T.; Ishihara, S.; Obeidat, A. M.; Adamczyk, N. S.; Hunter, R. S.; Li, J.; Wang, L.; Lee, H.; Ko, F. C.; Malfait, A.-M.; Miller, R. E.
10.1101/2024.08.16.608301 — neuroscience — Posted on 2024-08-19
2283 Neural mechanisms of awareness of action
Jin, D. S.; Agdali, O.; Yadav, T.; Kronemer, S. I.; Kunkler, S.; Majumder, S.; Khurana, M.; McCusker, M. C.; Fu, I.; Khalaf, A.; Christison-Lagay, K. L.; Aerts, S. L.; Xin, Q.; Li, J.-J.; McGill, S. H.; Crowley, M. J.; Blumenfeld, H.
10.1101/2024.08.15.608153 — neuroscience — Posted on 2024-08-19
2287 Preparing to act follows Bayesian inference rules
Tarasi, L.; Tabarelli, C.; Covelli, M.; Ippolito, G.; Avenanti, A.; Romei, V.
10.1101/2024.08.16.608232 — neuroscience — Posted on 2024-08-19
2292 The Fragile X Messenger Ribonucleoprotein 1 regulates the morphology and maturation of human and rat oligodendrocytes
Ramesh, V.; Kougianou, I.; Tsoukala, E.; Kozic, Z.; Burr, K.; Viswanath, B.; Hampton, D.; Story, D.; Reddy, B. K.; Pal, R.; Dando, O. R.; Kind, P. C.; Chattarji, S.; Selvaraj, B. T.; Chandran, S.; Zoupi, L.
10.1101/2024.08.16.608069 — neuroscience — Posted on 2024-08-19
2294 Recon8D: A metabolic regulome network from oct-omics and machine learning
Schildcrout, R.; Smith, K.; Bhowmick, R.; Menon, S.; Kapadia, M.; Kurtz, E.; Coffeen-Vandeven, A.; Chandrasekaran, S.
10.1101/2024.08.17.608400 — systems biology — Posted on 2024-08-19
2296 A florigen-expressing subpopulation of companion cells expresses other small proteins and reveals a nitrogen-sensitive FT repressor
Takagi, H.; Ito, S.; Shim, J. S.; Kubota, A.; Hempton, A. K.; Lee, N.; Suzuki, T.; Yang, C.; Nolan, C. T.; Bubb, K. L.; Alexandre, C. M.; Kurihara, D.; Sato, Y.; Tada, Y.; Kiba, T.; Pruneda-Paz, J. L.; Queitsch, C.; Cuperus, J. T.; Imaizumi, T.
10.1101/2024.08.17.608367 — plant biology — Posted on 2024-08-19
2298 Serum metabolomics signatures after an acute bout of combined traditional or high-intensity tactical training in young males and females
Graham, Z. A.; PATHAK, K. V.; Garcia-Mansfield, K.; Lavin, K.; Torres, A.; McAdam, J.; Broderick, T.; Pirrotte, P.; Bamman, M.
10.1101/2024.08.16.608249 — physiology — Posted on 2024-08-19
2299 14-3-3 promotes sarcolemmal expression of cardiac CaV1.2 and nucleates isoproterenol-triggered channel super-clustering
Spooner, H. C.; Costa, A. D.; Hernandez Gonzalez, A.; Ibrahimkhail, H.; Yarov-Yarovoy, V.; Horne, M.; Dickson, E. J.; Dixon, R. E.
10.1101/2024.08.16.607987 — physiology — Posted on 2024-08-19
2303 Primary culture of high grade serous ovarian cancer cells, selection and derivation of three cell lines
Brenton, J. D.; Vias, M.; Sauer, C. M.; Funingana, G.; Piskorz, A. M.; Moore, E.; Chilamakuri, C.; Hall, D.; Goranova, T.; Van Oudenhove, E.; Earl, H. M.; Goldlust, I.
10.1101/2024.08.15.607946 — cancer biology — Posted on 2024-08-19
2304 A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancer
Walke, P.; Price, J. D.; Vizeacoumar, F. S.; Joseph, N.; Maranda, V.; Chowdhury, B.; Patel, J.; Zhang, Y.; Dong, H.; New, L.; Ganapathysamy, A.; Gong, L. H.; Elhasasna, H.; Bhanumathy, K. K.; Wu, Y.; Freywald, A.; Krishnan, A.; Vizeacoumar, F.
10.1101/2024.08.16.607954 — cancer biology — Posted on 2024-08-19
2309 cytoKernel: Robust kernel embeddings for assessing differential expression of single cell data
Ghosh, T.; Baxter, R. M.; Seal, S.; Lui, V. G.; Rudra, P.; Vu, T.; Hsieh, E. W.; Ghosh, D.
10.1101/2024.08.16.608287 — bioinformatics — Posted on 2024-08-19
2315 Quantized multi-task learning for context-specific representations of gene network dynamics
Chen, H.; Venkatesh, M. S.; Gomez Ortega, J.; Mahesh, S. V.; Nandi, T. N.; Madduri, R. K.; Pelka, K.; Theodoris, C. V.
10.1101/2024.08.16.608180 — bioinformatics — Posted on 2024-08-19
2316 Contrastive learning for cell division detection and tracking in live cell imaging data
Zyss, D.; Sharma, A.; Ribeiro, S. A.; Repellin, C. E.; Lai, O.; Walter, T.; Fehri, A.
10.1101/2024.08.16.608296 — bioinformatics — Posted on 2024-08-19
2317 Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV.
Espinoza, P.; Cheng, M.; Ng, C.; De La Cruz, D.; Wasson, E. D.; McCarthy, D. M.; Bhide, P. G.; Maguire, C. A.; Santoscoy, M. C.
10.1101/2024.08.16.608303 — bioengineering — Posted on 2024-08-19
2318 Speckle contrast optical spectroscopy improves cuffless blood pressure estimation compared to photoplethysmography
Garrett, A.; Kim, B.; Gurel, N. Z.; Sie, E. J.; Wilson, B. K.; Marsili, F.; Forman, J. P.; Hamburg, N. M.; Boas, D. A.; Roblyer, D.
10.1101/2024.08.16.608163 — bioengineering — Posted on 2024-08-19
2320 Exploring ancestry inference of the Middle East
Herrick, N.; Ghemrawi, M.; Singh, S.; Mahfouz, R.; Walsh, S.
10.1101/2024.08.15.607793 — genetics — Posted on 2024-08-19
2322 Mutualisms within light microhabitats drive sensory convergence in a mimetic butterfly community
Wainwright, J. B.; Loupasaki, T.; Ramirez, F.; Penry-Williams, I. L.; England, S. J.; Barker, A.; Meier, J.; How, M. J.; Roberts, N. W.; Troscianko, J.; Montgomery, S. H.
10.1101/2024.08.16.607924 — evolutionary biology — Posted on 2024-08-19
2323 Novel use of global occurrence data to indirectly predict suitable habitats for widely distributed marine species in data-scarce regions
De Wysiecki, A. M.; Barnett, A.; Sanchez-Carnero, N. B.; Cortes, F.; Milessi, A. C.; Trobbiani, G. A.; Jaureguizar, A. J.
10.1101/2024.08.15.608095 — ecology — Posted on 2024-08-19
2326 Insect size responses to climate changes vary across elevations according to seasonal timing
Nufio, C.; Sheffer, M.; Smith, J.; Troutman, M.; Bawa, S.; Taylor, E.; Schoville, S.; Williams, C.; Buckley, L.
10.1101/2024.08.15.608059 — ecology — Posted on 2024-08-19
2327 A simple inland culture system provides insights into ascidian post-embryonic developmental physiology
Mathiesen, B. T.; Ohta, M.; Magalhaes, B. P. D.; Castelletti, C.; Perria, V.; Christiaen, L.; Ohta, N.
10.1101/2024.08.16.608202 — developmental biology — Posted on 2024-08-19
2328 A human induced pluripotent stem (hiPS) cell model for the holistic study of epithelial to mesenchymal transitions (EMTs)
Hookway, C.; Borensztejn, A.; Harris, L. K.; Carlson, S.; Dalgin, G.; Mishra, S.; Nivedita, N.; Adams, E. M.; Barszczewski, T.; Dixon, J. C.; Edmonds, J. H.; Ehlers, E. A.; Ferrante, A. J.; Fuqua, M. A.; Garrison, P.; Gopalan, J.; Gregor, B. W.; Hedayati, M. J.; Klein, K. N.; Leveille, C. L.; Meharry, S. L.; Morris, H. S.; Nadarajan, G.; Oluoch, S. A.; Parent, S. E.; Phan, A.; Roberts, B.; Sanchez, E. E.; Sluzewski, M. F.; Snyder, L. S.; Thirstrup, D. J.; Thottam, J. P.; Torvi, J. R.; Turman, G.; Viana, M. P.; Wilhelm, L.; Wijesooriya, C. S.; Yao, J.; Theriot, J. A.; Rafelski, S. M.; Gunawarda
10.1101/2024.08.16.608353 — cell biology — Posted on 2024-08-19
2329 Investigating Polyreactivity of CD4+ T Cells to the Intestinal Microbiota
Saadawi, A.; Mair, F.; Rosenwald, E.; Hoces, D.; Slack, E.; Kopf, M.
10.1101/2024.08.15.607895 — immunology — Posted on 2024-08-19
2331 Gut Microbiota and DTI Microstructural Brain Alterations in Rodents Due to Morphine Self-Administration
Brunetti, K.; Zhou, Z.; Shuchi, S.; Berry, R.; Zhang, Y.; Allen, M. S.; Yang, S.; Figueroa, J. D.; Colon-Perez, L.
10.1101/2024.08.15.608127 — neuroscience — Posted on 2024-08-19
2334 Comparison of test-retest reproducibility of DESPOT and 3D-QALAS for water T1 and T2 mapping
Simegn, G. L.; Gagoski, B.; Song, Y.; Dean, D. C.; Hupfelda, K. E.; Murali-Manohara, S.; Davies-Jenkinsa, C. W.; Simicic, D.; Wisnowskij, J.; Yedavallia, V.; Gudmundson, A. T.; Zollner, H. J.; Oeltzschner, G.; Edden, R. A. E.
10.1101/2024.08.15.608081 — neuroscience — Posted on 2024-08-19
2336 Sex differences in nucleus accumbens core circuitry engaged by binge-like ethanol drinking
Chan, A. E.; Anderson, J. Q.; Grigsby, K. E.; Jensen, B. E.; Ryabinin, A. E.; Ozburn, A. R.
10.1101/2024.08.15.608144 — neuroscience — Posted on 2024-08-19
2338 Rapid and Sensitive Detection of Fusarium oxysporum f. sp. cubense Tropical Race 4 Using a RPA-DETECTR Assay
Venkatesh, J.; Jankowicz-Cieslak, J.; Mduma, H.; Matijevic, M.; Ali, A.; Calle Balbin, I. C.; Soto-Suarez, M.; Zorrilla, C.; Bhatnagar-Mathur, P.
10.1101/2024.08.15.608054 — pathology — Posted on 2024-08-19
2339 Restraint of melanoma progression by cells in the local skin environment
Ma, Y.; Tagore, M.; Hunter, M. V.; Huang, T.-H.; Montal, E.; Weiss, J. M.; White, R. M.
10.1101/2024.08.15.608067 — cancer biology — Posted on 2024-08-19
2342 Eye-Opening Advances: Automated 3D Segmentation, Key Biomarkers Extraction, and the First Large-Scale MRI Eye Atlas.
Barranco Hernandez, J.; Luyken, A.; Kebiri, H.; Stachs, P.; Macias Gordaliza, P.; Esteban, O.; Aleman Gomez, Y.; Sznitman, R.; Stachs, O.; Langner, S.; Franceschiello, B.; Bach Cuadra, M.
10.1101/2024.08.15.608051 — bioengineering — Posted on 2024-08-19
2343 Dynamic assembly of pentamer-based protein nanotubes
Koziej, L.; Fatehi, F.; Aleksejczuk, M.; Byrne, M. J.; Heddle, J. G.; Twarock, R.; Azuma, Y.
10.1101/2024.08.15.608090 — bioengineering — Posted on 2024-08-19
2349 The Rab7-Epg5 and Rab39-ema modules cooperately position autophagosomes for efficient lysosomal fusions
Boda, A.; Balazs, V.; Nagy, A.; Hargitai, D.; Lippai, M.; Simon-Vecsei, Z.; Molnar, M.; Fürstenhoffer, F.; Juhasz, G.; Lörincz, P.
10.1101/2024.08.16.608254 — cell biology — Posted on 2024-08-19
2350 Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy
Lim, T. L.; Morral, C.; Verginadis, I. I.; Kim, K.; Luo, L.; Foley, C. J.; Kim, M. M.; Li, N.; Yoshor, B.; Njah, K.; Putt, M.; Oliaei Motlagh, S. A.; Velalopoulou, A.; Chowdhury, P.; Bicher, S.; Goia, D.; Lengner, C. J.; Wrana, J. L.; Koumenis, C.; Minn, A. J.
10.1101/2024.08.16.608284 — cell biology — Posted on 2024-08-19
2351 The Clonal Hematopoiesis-associated Gene Srcap Plays an Essential Role in Hematopoiesis
Wong, T. N.; Mychalowych, A.; Feldpausch, E. R.; Carson, A.; Karpova, D.; Link, D. C.
10.1101/2024.08.16.607812 — cell biology — Posted on 2024-08-19
2352 Berberine is a novel mitochondrial calcium uniporter (MCU) inhibitor that disrupts MCU-EMRE assembly
Zhao, H.; Chen, S.; Cao, N.; Wu, W.; Liu, G.; Gao, J.; Chen, J.; Li, T.; Lu, D.; Zeng, L.; Zhu, H.; Zhang, W.; Xia, Q.; Li, T.; Zhou, T.; Zhang, X.-M.; Li, A.-L.; Pan, X.
10.1101/2024.08.18.607892 — cell biology — Posted on 2024-08-19
2355 Low-level features predict perceived similarity for naturalistic images
A-Izzeddin, E. J.; Wallis, T. S. A.; Mattingley, J. B.; Harrison, W. J.
10.1101/2024.08.15.607867 — neuroscience — Posted on 2024-08-19
2358 Combining Gamma Neuromodulation and Robotic Rehabilitation Restores Parvalbimin-mediated Gamma Function and Boosts Motor Recovery in Stroke Mice
Vignozzi, L.; Macchi, F.; Montagni, E.; Pasquini, M.; Martello, A.; Minetti, A.; Coulomb, E.; Allegra Mascaro, A. L.; Micera, S.; Caleo, M.; Spalletti, C.
10.1101/2024.08.15.608060 — neuroscience — Posted on 2024-08-19
2359 Aquaporin-4 mis-localization slows glymphatic clearance of α-synuclein and promotes α-synuclein pathology and aggregate propagation
Braun, M.; Simon, M. J.; Jang, J.; Sanderson, K.; Swierz, J.; Sevao, M.; Pincus, A. B.; Schaser, A. J.; Elliott, J. E.; Lim, M. M.; Unni, V. K.; Schindler, A. G.; Keene, C. D.; Latimer, C. S.; Iliff, J.
10.1101/2024.08.14.607971 — neuroscience — Posted on 2024-08-19
2360 Seeing the Future: Anticipatory Eye Gaze as a Marker of Memory
Yamin, D.; Schmidig, F. J.; Sharon, O.; Nadu, Y.; Nir, J.; Ranganath, C.; Nir, Y.
10.1101/2024.08.14.607869 — neuroscience — Posted on 2024-08-19
2361 LncRNA 3222401L13Rik Is Up-regulated in Aging Astrocytes and Regulates Neuronal Support Function Through Interaction with Npas3
Schroeder, S.; Sakib, M. S.; Krueger, D. M.; Pena, T.; Burkhardt, S.; Schuetz, A.-L.; Sananbenesi, F.; Fischer, A.
10.1101/2024.08.14.607966 — neuroscience — Posted on 2024-08-19
2362 The heat sensitivity of sperm in the lizard Anolis sagrei
Wang, W. W.-Y.; Gunderson, A. R.; Page, N. R.; Strickler, A. M.; Kusaka, A. K.
10.1101/2024.08.14.607821 — zoology — Posted on 2024-08-19
2363 Immune checkpoint inhibitor treatment does not impair ovarian or endocrine function in a mouse model of triple negative breast cancer
De La Cruz, P.; Woodman-Sousa, M. F.; McAdams, J. N.; Sweeney, E.; Hakim, L.; Morales Aquino, M.; Grive, K. J.
10.1101/2024.08.14.607933 — cancer biology — Posted on 2024-08-19
2364 Extracellular Vesicles heterogeneity through the lens of multiomics
Silva, T. F.; Hutchins, E.; Zhao, W.; Ciani, Y.; Kim, M.; Mariscal, J.; Qiu, Z.; Kittel, A.; Zhou, B.; Wang, Y.; Hall, M.; Galasso, F.; Reiman, R.; Freeman, M. R.; Parker, S.; Van Eyk, J.; Yang, W.; Posadas, E.; Guarnerio, J.; Nolan, J.; Thery, C.; Zijlstra, A.; Stott, S.; You, S.; Demichelis, F.; Boutros, P.; Van Keuren-Jensen, K.; Di Vizio, D.
10.1101/2024.08.14.607999 — cancer biology — Posted on 2024-08-19
2368 Bio-macromolecular assembly machine for human limb lengthening
Xie, C.; Li, W.; Yao, X.; Wu, B.; Fang, J.; Mao, R.; Yan, Y.; Meng, H.; Wu, Y.; Zhang, X.; Duan, W.; Dai, X.; Wang, X.; Hongwei, O.
10.1101/2024.08.15.608028 — bioengineering — Posted on 2024-08-19
2371 Reconstituted high-density lipoproteins rescue diabetes-impaired endothelial cell metabolic reprograming and angiogenic responses to hypoxia
Primer, K. R.; Tan, J. T. M.; Sandeman, L.; Nankivell, V.; Stretton, L. G.; Solly, E.; Psaltis, P. J.; Bursill, C. A.
10.1101/2024.08.16.608361 — cell biology — Posted on 2024-08-19
2372 Dispersion indices for universal quantification of fluorescently-labelled subcellular structure spatial distributions
Grinstaff, M.; Martin, A.; Zhang, S.; Williamson, A.; Tingley, B.; Pickus, M.; Zurakowski, D.; Nia, H.; Shirihai, O. S.; Han, X. S.
10.1101/2024.08.18.608451 — cell biology — Posted on 2024-08-19
2373 An instantaneous voice synthesis neuroprosthesis
Wairagkar, M.; Card, N. S.; Singer-Clark, T.; Hou, X.; Iacobacci, C.; Hochberg, L. R.; Brandman, D. M.; Stavisky, S. D.
10.1101/2024.08.14.607690 — neuroscience — Posted on 2024-08-19
2374 Genetic differentiation and adaptive evolution of buff-tailed bumblebees in Asia
Su, L.; Din, L.; Williams, P. H.; Liu, Y.; Wang, R.; Dai, X.; Zhao, S.; Fu, H.; Zhao, X.; Wang, Q.; Li, Y.; Sang, H.; Waterhouse, R. M.; Zhai, Y.; Sun, C.
10.1101/2024.08.13.607144 — bioinformatics — Posted on 2024-08-19
2375 Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells
Sahu, S.; Castro, M.; Muldoon, J. J.; Asija, K.; Wyman, S. K.; Krishnappa, N.; de Onate, L.; Eyquem, J.; Nguyen, D. N.; Wilson, R. C.
10.1101/2024.07.14.603391 — bioengineering — Posted on 2024-08-19
2376 Polarization gratings aided common-path Hilbert holotomography for high-throughput lipid droplets content assay
Zdankowski, P.; Winnik, J.; Rogalski, M.; Marzejon, M. J.; Wdowiak, E.; Dudka, W.; Jozwik, M.; Trusiak, M.
10.1101/2024.06.14.598984 — bioengineering — Posted on 2024-08-19
2378 DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice
Wang, X.; Shen, G.; Yang, Y.; Jiang, C.; Ruan, T.; Yang, X.; Zhuo, L.; Zhang, Y.; Ou, Y.; Zhao, X.; Long, S.; Tang, X.; Lin, T.; Shen, Y.
10.1101/2024.02.19.580977 — genetics — Posted on 2024-08-19
2381 Body mass change over winter is consistently sex-specific across roe deer (Capreolus capreolus) populations
Hewison, A. J. M.; Bonnot, N.; Gaillard, J.-M.; Kjellander, P.; Lemaitre, J.-F.; Morellet, N.; Pellerin, M.
10.1101/2022.09.09.507329 — ecology — Posted on 2024-08-19
2383 Maternal prenatal stress induces sex-dependent changes in tRNA fragment families and cholinergic pathways in newborns
Vaknine Treidel, S.; Lobmaier, S.; Sharma, R.; Madrer, N.; Shulman, D.; Greenberg, P.; Bennett, E. R.; Greenberg, D. S.; Turjeman, A.; Zelgert, C.; Zimmermann, P.; Frasch, M. G.; Carmel, L.; Antonelli, M. C.; Soreq, H.
10.1101/2024.07.10.602894 — molecular biology — Posted on 2024-08-19
2384 A Single Mutation in an Enteric Virus Alters Tropism and Sensitivity to Microbiota
Erickson, A. K.; Sutherland, D. M.; Welsh, O. L.; Maples, R. W.; Dermody, T. S.; Pfeiffer, J. K.
10.1101/2024.08.16.608258 — microbiology — Posted on 2024-08-19
2386 Heterogeneous and non-random cortical connectivity undergirds efficient, robust and reliable neural codes
Egas Santander, D.; Pokorny, C.; Ecker, A.; Lazovskis, J.; Santoro, M.; Smith, J. P.; Hess, K.; Levi, R.; Reimann, M. W.
10.1101/2024.03.15.585196 — neuroscience — Posted on 2024-08-19
2388 Toss GERALT into chloroplast to make it green: a new regulator of chloroplast biogenesis and chlorophyll biosynthesis
Banas, A. K.; Grzyb, J.; Zglobicki, P.; Pacak, A.; Mysliwa-Kurdziel, B.; Leja, K.; Kozieradzka-Kiszkurno, M.; Klodawska, K.; Konieczny, R.; Pilarska, M.; Niewiadomska, E.; Bazant, A.; Szewc, L.; Kowalska, E. B.; Strzalka, W.
10.1101/2024.08.16.608208 — plant biology — Posted on 2024-08-19
2390 A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells
Babin-Ebell, A.; Mao, Y.; Baljkas, T.; Wiedmann, F.; Pilz, F.; Winkler, M.; Kuerschner-Zacharias, S. W.; Hoffarth, M.; Schmidt, C.; Goerdt, S.; Reiners-Koch, P.-S.; Singhal, M.
10.1101/2024.03.11.584492 — physiology — Posted on 2024-08-19
2392 Cell type and locus-specific epigenetic editing of memory expression
Coda, D. M.; WATT, L.; glauser, l.; Batiuk, M.; Burns, A.; Stahl, C.; Graeff, J.
10.1101/2024.08.18.608454 — neuroscience — Posted on 2024-08-18
2394 Loss of Zmiz1 in mice leads to impaired cortical development and autistic-like behaviors
K C, R.; Patel, N. R.; Thurmon, A. N.; Lorino, M. G.; Tiemroth, A. S.; Kulstad, I.; Morrison, V.; Akumuo, M.; Shenoy, A.; Meadows, S. M.; Galazo, M. J.
10.1101/2024.08.18.608498 — neuroscience — Posted on 2024-08-18
2396 Task-related activity in auditory cortex enhances sound representation
Polterovich, A.; Jankowski, M. M.; Niediek, J.; Kazakov, A.; Nelken, I.
10.1101/2024.08.18.608392 — neuroscience — Posted on 2024-08-18
2398 Prelimbic corticopontine neurons gate extinction learning
Lee, H.-R.; Choi, S. H.; Kim, Y.; Ko, S.; Kang, H.; Lee, I.; Park, A. J.; Lee, S.-H.
10.1101/2024.08.14.607871 — neuroscience — Posted on 2024-08-18
2399 FLASH radiotherapy using high-energy X-rays: validation of the FLASH effect triggered by a compact single high-energy X-ray source device
Lin, B.; Du, H.; Yang, Y.; Hao, X.; Gao, F.; Liang, Y.; Tang, W.; Xu, H.; Tang, M.; Liao, Y.; Wang, D.; Lin, B.; Zhu, Y.; Wang, T.; Gu, R.; Miao, X.; He, Y.; Li, J.; zhou, z.; Wang, J.; Wu, D.; Du, X.
10.1101/2024.07.16.603758 — cancer biology — Posted on 2024-08-18
2403 CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development
Ji, L.; Wang, A.; Sonthalia, S.; Naiman, D. Q.; Younes, L.; Colantuoni, C.; Geman, D.
10.1101/2023.04.06.535943 — genomics — Posted on 2024-08-18
2407 Live-Cell Quantification Reveals Viscoelastic Regulation of Synapsin Condensates by α-Synuclein
Wang, H.; Hoffmann, C.; Tromm, J. V.; Su, X.; Elliott, J.; Wang, H.; Baum, J.; Pang, Z. P.; Milovanovic, D.; Shi, Z.
10.1101/2024.07.28.605529 — cell biology — Posted on 2024-08-18
2409 Engineered transcription-associated Cas9 targeting in eukaryotic cells
Goldberg, G. W.; Kogenaru, M.; Keegan, S.; Haase, M. A. B.; Kagermazova, L.; Arias, M. A.; Onyebeke, K.; Adams, S.; Beyer, D. K.; Fenyo, D.; Noyes, M. B.; Boeke, J. D.
10.1101/2023.09.18.558319 — molecular biology — Posted on 2024-08-18
2410 Dietary Bioactive Compounds Trigger Distinct Epigenetic and Metabolic Reprogramming in Lactobacillus acidophilus
Kong, Y.; Adejoro, D. O.; Wescombe, P. A.; Winefield, C.; On, S. L. W.; Mitchell, N. L.; Subbaraj, A.; Saunders, A.; Maes, E.; Chelikani, V.
10.1101/2024.08.18.608491 — microbiology — Posted on 2024-08-18
2411 Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice
Nash, A. N.; Shakeshaft, M.; Bouaichi, C. G.; Odegaard, K. E.; Needham, T.; Bauer, M.; Bertram, R.; Vincis, R.
10.1101/2024.04.27.591293 — neuroscience — Posted on 2024-08-18
2413 Motor training improves impaired cortico-cerebellar connectivity in cerebellar ataxia
Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.
10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-08-18
2414 Insect hormone PTTH regulates lifespan through temporal and spatial activation of NF-κB signaling during metamorphosis
Kang, P.; Liu, P.; Kim, J.; Kumar, A.; Bolton, M.; Murzyn, W. A.; Anderson, Z. J.; Frank, L. N.; Kavlock, N.; Hoffman, E.; Martin, C. C.; Dorneich-Hayes, M. K.; Miao, T.; Shimell, M.; Chen, W.; Hu, Y.; Powell-Coffman, J.; O'Connor, M. B.; Perrimon, N.; Bai, H.
10.1101/2023.09.30.560323 — physiology — Posted on 2024-08-18
2419 A dynamic compositional equilibrium governs mRNA recognition by eIF3
Ide, N. A.; Gentry, R. C.; Rudbach, M. A.; Yoo, K.; Velez, P. K.; Communale, V. M.; Hartwick, E. W.; Kinz-Thompson, C. D.; Gonzalez, R. L.; Aitken, C. E.
10.1101/2024.04.25.581977 — biophysics — Posted on 2024-08-18
2420 Ligand-Mediated Endocytosis Is Regulated in a Sexually Dimorphic Way in Osteocytes in vivo
Matthews, M. D.; Saffari, A. W.; Mukul, N. A.; Hai, J.; Wiesner, U. B.; Lewis, K. J.
10.1101/2024.08.18.608500 — bioengineering — Posted on 2024-08-18
2423 Disease and ectoparasite management improve nestling golden eagle health and survival: An effective mitigation strategy
Heath, J. A.; Davis, C. M.; Dudek, B. M.; McClure, C. J. W.; Myers, K. T.; Regnier, E. K.; Rolek, B. W.; Santiago, A. L.
10.1101/2024.08.14.607861 — ecology — Posted on 2024-08-18
2424 Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF-Trap
Destan, E.; Turkut, E.; Aldeniz, A.; Kang, J.; Tosha, T.; Yabashi, M.; Yilmaz, B.; Timucin, A. C.; Matsuura, H.; Kawano, Y.; Cinkaya, I.; DeMirci, H.
10.1101/2024.08.18.608484 — molecular biology — Posted on 2024-08-18
2425 Dietary Bioactive Compounds Trigger Distinct Epigenetic and Metabolic Reprogramming in Lactobacillus acidophilus
Kong, Y.; Adejoro, D. O.; Wescombe, P. A.; Winefield, C.; On, S. L. W.; Mitchell, N. L.; Subbaraj, A.; Saunders, A.; Maes, E.; Chelikani, V.
10.1101/2024.08.18.608491 — microbiology — Posted on 2024-08-18
2427 Opsin-based photoreception in Crinoids
Nonclercq, Y.; Lienard, M.; Lourtie, A.; Duthoo, E.; Vanespen, L.; Eeckhaut, I.; Flammang, P.; Delroisse, J.
10.1101/2024.08.14.607903 — zoology — Posted on 2024-08-18
2429 Finding the E-Channel Proton Loading Sites by Calculating the Ensemble of Protonation Microstates
Uddin, M. R.; Khaniya, U.; Gupta, C.; Mao, J.; Ranepura, G.; Wei, R.; Soto, J. O.; Singharoy, A.; Gunner, M.
10.1101/2024.08.14.608010 — biophysics — Posted on 2024-08-18
2432 Kinetics of i-motif folding within the duplex context
Alieva, R.; Keshek, A.; Zatsepin, T.; Orlov, V.; Aralov, A.; Zavyalova, E.
10.1101/2024.08.18.608433 — biochemistry — Posted on 2024-08-18
2433 Benchmarking DNA Foundation Models for Genomic Sequence Classification
Feng, H.; Wu, L.; Zhao, B.; Huff, C.; Zhang, J.; Wu, J.; Lin, L.; Wei, P.; Wu, C.
10.1101/2024.08.16.608288 — genomics — Posted on 2024-08-18
2434 Genetic variations associated with adaptation processes in Acrocomia palms: A comparative study across the Neotropic for future crop improvement
Morales-Marroquin, J. A.; Diaz-Hernandez, B. G.; Vianna, S. A.; Alves-Pereira, A.; de Araujo-Batista, C. E.; Colombo, C. A.; Pinheiro, J. B.; Zucchi, M. I.
10.1101/2024.08.15.608149 — genomics — Posted on 2024-08-18
2436 Comparative Transcriptomes of Canine and Human Prostate Cancers Identify Mediators of Castration Resistance
Angel, M. R.; Seguin, B.; Lohr, C. V.; Beer, T.; Feliciano, J.; Ramsey, S. A.; Thomas, G. V.
10.1101/2024.08.18.608482 — genetics — Posted on 2024-08-18
2437 Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context
Salnikov, P. A.; Belokopytova, P. S.; Yan, A. P.; Viesna, E.; Korablev, A. N.; Serova, I. A.; Lukyanchikova, V. A.; Stepanchuk, Y. K.; Torgunakov, N. Y.; Tikhomirov, S. A.; Fishman, V. S.
10.1101/2024.08.16.608309 — genetics — Posted on 2024-08-18
2438 Gut microbiota dysbiosis induced by brain tumor modulates the efficacy of immunotherapy
Kim, H. C.; Kim, H.-J.; La, J.; Park, W. H.; Park, S. H.; Kang, B. H.; Kim, Y.; Lee, H. K.
10.1101/2024.08.18.608488 — microbiology — Posted on 2024-08-18
2440 Genome-resolved diversity and biosynthetic potential of the coral reef microbiome
Paoli, L.; Wiederkehr, F.; Ruscheweyh, H.-J.; Miravet-Verde, S.; Bistolas, K. S. I.; Sawyer, T.; Labadie, K.; Mayer, K.-I.; Perdereau, A.; Reddy, M. M.; Moulin, C.; Boissin, E.; Bourdin, G.; Cailliau, J.; Iwankow, G.; Poulain, J.; Romac, S.; Tara Pacific Consortium Coordinators, ; Planes, S.; Allemand, D.; Agostini, S.; Bowler, C.; Douville, E.; Forcioli, D.; Galand, P. E.; Lombard, F.; Oliveira, P. H.; Piel, J.; Thomas, O.; Thurber, R. V.; Trouble, R.; Voolstra, C. R.; Wincker, P.; Ziegler, M.; Sunagawa, S.
10.1101/2024.08.18.608444 — microbiology — Posted on 2024-08-18
2442 ETS TRANSCRIPTION FACTOR POINTED CONTROLS GERMLINE SURVIVAL IN DROSOPHILA
Rosales-Nieves, A. E.; Marin-Menguiano, M.; Lopez-Onieva, L.; Garrido-Maraver, J.; Gonzalez-Reyes, A.
10.1101/2024.08.15.608137 — developmental biology — Posted on 2024-08-18
2444 Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins
Thorwald, M. A.; Godoy-Lugo, J. A.; Santa Maria, N.; Chakhoyan, A.; O'Day, P.; Jacobs, R.; Zlokovic, B.; Finch, C.
10.1101/2024.08.14.607970 — neuroscience — Posted on 2024-08-18
2450 Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress
Nhung, T. T. M.; Phat, N. K.; Anh, T. T.; Nghi, T. D.; Thu, N. Q.; Lee, A.; Tien, N. T. N.; Anh, N. K.; Kim, K.; Nguyen, D. N.; Kim, D. H.; Park, S. K.; Long, N. P.
10.1101/2024.08.12.607527 — pharmacology and toxicology — Posted on 2024-08-17
2451 The genetic architecture of cell-type-specific cis-regulation
Marand, A. P.; Jiang, L.; Gomez-Cano, F. A.; Minow, M. A. A.; Zhang, X.; Mendieta, J. P.; Luo, Z.; Bang, S.; Yan, H.; Meyer, C.; Schlegel, L.; Johannes, F.; Schmitz, R. J.
10.1101/2024.08.17.608383 — genetics — Posted on 2024-08-17
2452 Cyclic di-GMP as an Antitoxin Regulates Bacterial Genome Stability and Antibiotic Persistence in Biofilms
Liao, H.; Yan, X.; Wang, C.; Huang, C.; Zhang, W.; Xiao, L.; Jiang, J.; Bao, Y.; Huang, T.; Zhang, H.; Guo, C.; Zhang, Y.; Pu, Y.
10.1101/2024.05.22.595364 — microbiology — Posted on 2024-08-17
2453 Hedgehog signaling controls cytotoxic T cell migration in the tumour microenvironment.
Kapeni, C.; O'Brien, L.; Sabirova, D.; Cast, O.; Carbonaro, V.; Clark-Leonard, S.; Beke, F.; McDonald, S.; Fife, K.; de la Roche, M.
10.1101/2024.08.14.607917 — immunology — Posted on 2024-08-17
2456 Next generation AMA1-based plasmids for enhanced heterologous expression in filamentous fungi
Roux, I.; Woodcraft, C.; Sbaraini, N.; Pepper, A.; Wong, E.; Bracegirdle, J.; Chooi, Y.-H.
10.1101/2024.06.01.596972 — synthetic biology — Posted on 2024-08-17
2457 Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress
Nhung, T. T. M.; Phat, N. K.; Anh, T. T.; Nghi, T. D.; Thu, N. Q.; Lee, A.; Tien, N. T. N.; Anh, N. K.; Kim, K.; Nguyen, D. N.; Kim, D. H.; Park, S. K.; Long, N. P.
10.1101/2024.08.12.607527 — pharmacology and toxicology — Posted on 2024-08-17
2459 Mechanical strain focusing at topological defect sites in regenerating Hydra
Maroudas-Sacks, Y.; Suganthan, S.; Garion, L.; Ascoli-Abbina, Y.; Westfried, A.; Dori, N.; Pasvinter, I.; Popovic, M.; Keren, K.
10.1101/2024.06.13.598802 — biophysics — Posted on 2024-08-17
2465 Single-cell and spatial transcriptomics of vulvar lichen sclerosus reveal multicompartmental alterations in gene expression and signaling cross-talk
Sun, P.; Kraus, C. N.; Zhao, W.; Xu, J.; Suh, S.; Nguyen, Q.; Jia, Y.; Nair, A.; Oakes, M.; Tinoco, R.; Shiu, J.; Sun, B.; Elsensohn, A. N.; Atwood, S. X.; Nie, Q.; Dai, X.
10.1101/2024.08.14.607986 — genomics — Posted on 2024-08-17
2466 Analysis of 3.6 million individuals yields minimal evidence of pairwise genetic interactions for height
Jabalameli, M. R.; Holmes, M. V.; Hinds, D.; 23andMe Research Team, ; Auton, A.; Fontanillas, P.
10.1101/2024.08.15.608197 — genomics — Posted on 2024-08-17
2469 Diverse Genotype-by-Weather Interactions in Switchgrass
MacQueen, A. H.; Zhang, L.; Smith, S.; Bonette, J.; Boe, A. R.; Fay, P. A.; Fritschi, F. B.; Lowry, D. B.; Mitchell, R. B.; Rouquette, F. M.; Wu, Y.; Harpak, A.; Juenger, T. E.
10.1101/2021.08.19.456975 — genetics — Posted on 2024-08-17
2470 Valine restriction extends survival in a Drosophila model of short-chain enoyl-CoA hydratase 1 (ECHS1) deficiency
Mele, S.; Martelli, F.; Barlow, C.; Jefferies, G.; Dworkin, S.; Christodoulou, J.; Schittenhelm, R. B.; Piper, M. D.; Johnson, T. K.
10.1101/2024.08.15.608013 — genetics — Posted on 2024-08-17
2471 The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis
Kim, S.; Yamada, S.; Li, T.; Canasto-Chibuque, C.; Kim, J. H.; Marcet-Ortega, M.; Xu, J.; Eng, D. Y.; Feeney, L.; Petrini, J. H. J.; Keeney, S.
10.1101/2024.08.17.608390 — genetics — Posted on 2024-08-17
2476 Worldwide Soundscapes: a synthesis of passive acoustic monitoring across realms
Darras, K. F.; Rountree, R.; Van Wilgenburg, S.; Cord, A. F.; Chen, Y.; Dong, L.; Rocquencourt, A.; Desjonqueres, C.; Diaz, P. M.; Lin, T.-H.; Gasc, A.; Marley, S.; Salton, M.; Schille, L.; Wensveen, P. J.; Wu, S.-H.; Acevedo-Charry, O.; Adam, M.; Aguzzi, J.; Akoglu, I.; Amorim, M. C. P.; Andre, M.; Antonelli, A.; Aparecido Do Nascimento, L.; Appel, G.; Archer, S.; Astaras, C.; Atemasov, A.; Atkinson, J.; Attia, J.; Baltag, E.; Barbaro, L.; Basan, F.; Batist, C.; Baucells, A. L.; Baumgarten, J. E.; Bayle Sempere, J. T.; Bellisario, K.; Ben David, A.; Berger-Tal, O.; Betts, M. G.; Bhalla, I.; B
10.1101/2024.04.10.588860 — ecology — Posted on 2024-08-17
2478 RAD52 prevents accumulation of Polalpha-dependent replication gaps at perturbed replication forks in human cells
Di Biagi, L.; Marozzi, G.; Malacaria, E.; Honda, M.; Aiello, F. A.; Valenzisi, P.; Spies, M.; Franchitto, A.; Pichierri, P.
10.1101/2023.04.12.536536 — cell biology — Posted on 2024-08-17
2479 Neuromuscular dysfunction in patient-derived FUSR244RR-ALS iPSC model via axonal downregulation of neuromuscular junction proteins
von Kuegelgen, N.; Ludwik, K.; Mendonsa, S.; Roemer, C.; Becher, E.; Breimann, L.; Strauch, M.; Mari, T.; Mongellaz, S.; Grexa, N.; Oliveras-Martinez, A.; Woehler, A.; Selbach, M.; la Bella, V.; Ulitsky, I.; Chekulaeva, M.
10.1101/2024.08.17.607965 — cell biology — Posted on 2024-08-17
2480 Human Replication Protein A complex is a Telomerase Processivity Factor Essential for Telomere Maintenance
Agrawal, S.; Lin, X.; Susvirkar, V.; O'Connor, M. S.; Chavez, B. L.; Tholkes, V. R.; Abe, K. M.; He, Q.; Huang, X.; Lim, C. J.
10.1101/2024.08.16.608355 — molecular biology — Posted on 2024-08-17
2483 CAG repeat-selective compounds reduce abundance of expanded CAG RNAs in patient cell and murine models of SCAs
Shorrock, H. K.; Aliyeva, A.; Frias, J. A.; DeMeo, V. A.; Lennon, C. D.; DeMeo, C. C.; Merritt, A. K.; Shaughnessy, S.; Mazdiyasni, H.; Cleary, J. D.; Reddy, K.; Vangaveti, S.; Shin, D. S.; Berglund, J. A.
10.1101/2024.08.17.608349 — molecular biology — Posted on 2024-08-17
2485 A high-resolution view of RNA endonuclease cleavage in Bacillus subtilis
Taggart, J.; Dierksheide, J.; LeBlanc, H.; Lalanne, J.-B.; Durand, S.; Braun, F.; Condon, C.; Li, G.-W.
10.1101/2023.03.12.532304 — molecular biology — Posted on 2024-08-17
2489 Cross-linked agarose-gelatine beads as a substrate for investigating biofilms of bacterial pathogens
Roizman, D.; Herzog, M.; Nath, A.; Pachaimuthu, N.; Hujeirat, A.; Kuropka, B.; Rolff, J.; Rodriguez-Rojas, A.
10.1101/2024.08.16.608334 — microbiology — Posted on 2024-08-17
2490 Inhibition of glycolysis in tuberculosis-mediated metabolic rewiring reduces HIV-1 spread across macrophages
Vahlas, Z.; Faivre, N.; Monard, S.; Hertel, Q.; Maio, M.; Barros, J.; Lucas, A.; Phong, T.; Ben-Neji, M.; Corti, M.; Poincloux, R.; Blanchet, F.; Raynaud-Messina, B.; Letisse, F.; Neyrolles, O.; Lugo-Villarino, G.; Balboa, L.; Verollet, C.
10.1101/2024.08.14.607908 — immunology — Posted on 2024-08-17
2492 Human-specific features of cerebellar astrocytes and Purkinje cells: an anatomical comparison with mice and macaques
Hercher, C.; Ellerbeck, K.; Toutee, L.; Ye, X.; Mpai, R.; Davoli, M. A.; Watt, A. J.; Murai, K. K.; Turecki, G.; Mechawar, N.
10.1101/2024.08.13.607849 — neuroscience — Posted on 2024-08-17
2494 Fast, scalable, and statistically robust cell extraction from large-scale neural calcium imaging datasets
Dinc, F.; Inan, H.; Hernandez, O.; Schmuckermair, C.; Hazon, O.; Tasci, T.; Ahanonu, B. O.; Zhang, Y.; Lecoq, J.; Haziza, S.; Wagner, M. J.; Erdogdu, M. A.; Schnitzer, M. J.
10.1101/2021.03.24.436279 — neuroscience — Posted on 2024-08-17
2496 Triggering and modulation of a complex behavior by a single peptidergic command neuron in Drosophila
Fernandez-Acosta, M.; Zanini, R.; Heredia, F.; Volonte, Y.; Menezes, J.; Pruger, K.; Ibarra, J.; Arana, M.; Perez, M. S.; Veenstra, J. A.; Wegener, C.; Gontijo, A. M.; Garelli, A.
10.1101/2024.04.27.591209 — neuroscience — Posted on 2024-08-17
2497 C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles
Rostalski, H.; Hietanen, T.; Hoffmann, D.; Heikkinen, S.; Huber, N.; Dhingra, A.; Rodriguez-Nieto, S.; Kuulasmaa, T.; Ohtonen, S.; Jantti, H.; Pekkala, V.; Leskela, S.; Makinen, P.; Katisko, K.; Hartikainen, P.; Lehtonen, S.; Solje, E.; Koistinaho, J.; Malm, T.; Portaankorva, A. M.; Natunen, T.; Martiskainen, H.; Takalo, M.; Hiltunen, M.; Haapasalo, A.
10.1101/2024.08.14.607573 — neuroscience — Posted on 2024-08-17
2498 Motor training improves impaired cortico-cerebellar connectivity in cerebellar ataxia
Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.
10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-08-17
2500 Disrupted cardiac bioenergetics linked to oxidized mitochondrial creatine kinase are rescued by the mitochondrial-targeting peptide SBT-20 in the D2.mdx model of Duchenne muscular dystrophy
Perry, C. G. R.; Hughes, M. C.; Ramos, S. V.; Brahmbhatt, A.; Turnbull, P. C.; Polidovitch, N.; Garibotti, M. C.; Schlattner, U.; Hawke, T. J.; Simpson, J. A.; Backx, P. H.
10.1101/2024.02.04.578832 — physiology — Posted on 2024-08-17
2501 Single-molecule detection of transient dimerization of opioid receptors 1: Homodimers' effect on signaling and internalization
Zhou, P.; Tsunoyama, T. A.; Kasai, R. S.; Hirosawa, K. M.; Kalay, Z.; Aladag, A.; Fujiwara, T.; Pigolotti, S.; Kusumi, A.
10.1101/2024.07.25.605080 — biophysics — Posted on 2024-08-17
2503 Single-molecule detection of transient dimerization of opioid receptors 2: Heterodimer blockage reduces morphine tolerance
Zhou, P.; Kasai, R. S.; Fujita, W.; Tsunoyama, T. A.; Ueda, H.; Pigolotti, S.; Fujiwara, T.; Kusumi, A.
10.1101/2024.07.25.605109 — biophysics — Posted on 2024-08-17
2504 Genetic differentiation and adaptive evolution of buff-tailed bumblebees in Asia
Su, L.; Din, L.; Williams, P. H.; Liu, Y.; Wang, R.; Dai, X.; Zhao, S.; Fu, H.; Zhao, X.; Wang, Q.; Li, Y.; Sang, H.; Waterhouse, R. M.; Zhai, Y.; Sun, C.
10.1101/2024.08.13.607144 — bioinformatics — Posted on 2024-08-17
2507 Integrative genomics approach identifies glial transcriptomic dysregulation and risk in the cortex of individuals with Alcohol Use Disorder
Warden, A. S.; Salem, N. A.; Brenner, E.; Sutherland, G. T.; Stevens, J.; Kapoor, M.; Goate, A. M.; Mayfield, R. D.
10.1101/2024.08.16.607185 — neuroscience — Posted on 2024-08-17
2508 Phosphoryl group wires stabilize pathological tau fibrils as revealed by multiple quantum spin counting NMR
Potnuru, L. R.; DuBose, A.; Nowotarski, M. S.; Vigers, M.; Zhang, B.; Han, C.-T.; Han, S.
10.1101/2024.08.14.606685 — biophysics — Posted on 2024-08-17
2509 One pot RNA:DNA assembly for ribosomal RNA detection of pathogenic bacteria with single-molecule sensitivity
Boskovic, F. N.; Sandler, S.; Brauburger, S.; Shui, Y.; Kumar, B.; Pereira Dias, J.; Naydenova, P.; Zhu, J.; Baker, S.; Keyser, U. F.
10.1101/2024.08.15.608086 — biophysics — Posted on 2024-08-17
2511 Myosin forces elicit an F-actin structural landscape that mediates mechanosensitive protein recognition
Carl, A. G.; Reynolds, M. J.; Gurel, P. S.; Phua, D. Y.; Sun, X.; Mei, L.; Hamilton, K.; Takagi, Y.; Noble, A. J.; Sellers, J. R.; Alushin, G. M.
10.1101/2024.08.15.608188 — biophysics — Posted on 2024-08-17
2512 Multipartite complexity of the lichen symbiosis revealed by metagenome and transcriptome analysis of Xanthoria parietina
Tagirdzhanova, G.; Scharnagl, K.; Sahu, N.; Yan, X.; Bucknell, A.; Bentham, A. R.; Jegousse, C.; Ament-Velasquez, S. L.; Brännström, I. O.; Johannesson, H.; MacLean, D.; Talbot, N. J.
10.1101/2024.08.16.608140 — bioinformatics — Posted on 2024-08-17
2513 Steering cell-state and phenotype transitions by causal disentanglement learning
Zhang, C.; Chen, Z.; Miao, Y.; Xue, Y.; Cai, D.; Guo, W.; Ji, h.; Aihara, K.; Chen, L.
10.1101/2024.08.16.607277 — bioinformatics — Posted on 2024-08-17
2517 Ribosome-inactivation by a class of widely distributed C-tail anchored membrane proteins
Njenga, R.; Boele, J.; Drepper, F.; Sinha, K.; Marouda, E.; Huesgen, P. F.; Blaby-Haas, C.; Koch, H.-G.
10.1101/2024.08.16.608256 — biochemistry — Posted on 2024-08-17
2519 Comparison of Fixed Single Cell RNA-seq Methods to Enable Transcriptome Profiling of Neutrophils in Clinical Samples
Hatje, K.; Schneider, K.; Danilin, S.; Koechl, F.; Giroud, N.; Juglair, L.; Marbach, D.; Knuckles, P.; Bergauer, T.; Metruccio, M.; Garrido, A.; Zhang, J. D.; Sultan, M.; Bell, E.
10.1101/2024.08.14.607767 — genomics — Posted on 2024-08-17
2521 Excluding Large Grazers Dramatically Improves Survival of Outplanted Juvenile Corals
van der Steeg, E.; Humanes, A.; Bythell, J. C.; Craggs, J. R.; Edwards, A. J.; Golbuu, Y.; Lachs, L.; Miller, M. W.; Randle, J. L.; Guest, J. R.
10.1101/2024.08.15.607490 — ecology — Posted on 2024-08-17
2522 Formation of giant ER sheets by pentadecanoic acid causes lipotoxicity in fission yeast
Hoshikawa, Y.; Shirota, N.; Tsugawa, H.; Kimura, S.; Matsuyama, A.; Yashiroda, Y.; Kakeya, H.; Arita, M.; Iizumi, R.; Yoshida, M.; Nishimura, S.
10.1101/2024.08.15.608187 — cell biology — Posted on 2024-08-17
2523 Coral microbiomes from the Atlantic and Indo-Pacific oceans have the same alpha diversity but different composition
Santos, M. E. A.; Reimer, J. D.; Kiriukhin, B.; Wee, H. B.; Mizuyama, M.; Kise, H.; Kitahara, M. V.; Iguchi, A.; Dudoit, A.; Toonen, R. J.; Husnik, F.
10.1101/2024.08.16.608269 — microbiology — Posted on 2024-08-17
2524 A Single Mutation in an Enteric Virus Alters Tropism and Sensitivity to Microbiota
Erickson, A. K.; Sutherland, D. M.; Welch, O. L.; Maples, R. W.; Dermody, T. S.; Pfeiffer, J. K.
10.1101/2024.08.16.608258 — microbiology — Posted on 2024-08-17
2525 A genetically engineered therapeutic lectin inhibits human influenza A virus infection and sustains robust virus-specific CD8 T cell expansion
Yu, M.; Lin, A.; Baharom, F.; Li, S.; Legendre, M.; Coves-Datson, E.; Sohlberg, E.; Schlisio, S.; Lore, K.; Markovitz, D. M.; Smed-Sorensen, A.
10.1101/2024.08.15.608041 — immunology — Posted on 2024-08-17
2528 The genetic landscape of antibiotic sensitivity in Staphylococcus aureus
Li, W.; Liu, M.; Oikonomou, P.; Blattman, S. B.; Hettleman, J.; Gonzalez, J.; Chen, H.; Tavazoie, S.; Jiang, W.
10.1101/2024.08.15.608136 — systems biology — Posted on 2024-08-17
2531 Genome Instability Precedes Viral Integration in Human Papilloma Virus Transformed Tonsillar Keratinocytes
Chan, K.; Tseng, C.; Malarachi, E.; Goldrich, D.; Schneper, L.; Sheldon, K.; Alam, S.; Aliaga, C.; Chatterjee, S.; El-Bayoumy, K.; Meyers, C.; Goldenberg, D.; Broach, J. R.
10.1101/2024.08.14.607944 — cancer biology — Posted on 2024-08-17
2532 AVJ16 inhibits the RNA binding protein IGF2BP1 in lung adenocarcinomas and prevents tumor growth in mice
Wallis, N.; Gershon, T.; Shaaby, S.; Oberman, F.; Grunewald, M.; Duran, D.; Singh, A.; Vainer, G.; Spiegelman, V. S.; Sharma, A. K.; Yisraeli, J. K.
10.1101/2024.08.15.608038 — cancer biology — Posted on 2024-08-17
2533 A range of voltage-clamp protocol designs for rapid capture of hERG kinetics
Lei, C. L.; Whittaker, D. G.; Windley, M. J.; Perry, M. D.; Hill, A. P.; Mirams, G. R.
10.1101/2024.08.14.607756 — biophysics — Posted on 2024-08-17
2534 Sidelobe suppressed Bessel beams for one-photon light-sheet microscopy
Taneja, C.; George, J. G.; Corsetti, S.; Wijesinghe, P.; Bruce, G. D.; Zwart, M. F.; Bhattacharya, S.; Dholakia, K.
10.1101/2024.08.15.607323 — biophysics — Posted on 2024-08-17
2538 Large protein databases reveal structural complementarity and functional locality
Szczerbiak, P.; Szydlowski, L.; Wydmanski, W.; Renfrew, P. D.; Koehler Leman, J.; Kosciolek, T.
10.1101/2024.08.14.607935 — bioinformatics — Posted on 2024-08-17
2542 Origins of de novo chromosome rearrangements unveiled by coupled imaging and genomics
Cosenza, M. R.; Gaiatto, A.; Erarslan Uysal, B.; Andrades Delgado, A.; Sautter, N. L.; Jendrusch, M. A.; Zumalave Duro, S.; Rausch, T.; Halavatyi, A.; Geissen, E.-M.; Hasenfeld, P.; Cortes-Ciriano, I.; Kulozik, A.; Pepperkok, R.; Korbel, J. O.
10.1101/2024.08.15.607890 — genomics — Posted on 2024-08-17
2543 WheresWalker: a pipeline for rapid mutation mapping using whole genome sequencing
Feltes, M.; Zimin, A. V.; Angel, S.; Pansari, N.; Hensley, M. R.; Anderson, J. L.; Shen, M.-C.; Klemek, M.; Shen, Y.; Ginde, V. S.; Truong, V. P.; Kozan, H.; Le, N. V.; Wilson, M. H.; Salzberg, S. L.; Farber, S. A.
10.1101/2024.08.14.607950 — genetics — Posted on 2024-08-17
2544 Ground nesting of soft eggs by extinct birds and a new parity mode switch hypothesis for the evolution of animal reproduction
Guimaraes, M. J.; Wang, J.; Zhang, X.; Sun, Q.; Cerqueira, M. F.; Chung, Y.-H.; Deng, R.; Guo, B.; Alpuim, P.; Ma, F.; Wang, X.; Yen, T.-C.
10.1101/2024.08.15.607182 — evolutionary biology — Posted on 2024-08-17
2545 Differences in energy storage in sympatric salmonid morphs with contrasting lifestyles
Esin, E. V.; N. Markevich, G. N.; Shulgina, E. V.; Baskakova, Y. A.; Atemov, R. V.; Shkil, F. N.
10.1101/2024.08.14.607877 — evolutionary biology — Posted on 2024-08-17
2547 Tryptophanase disruption underlies the evolution of insect-bacterium mutualism
Wang, Y.; Moriyama, M.; Koga, R.; Oguchi, K.; Hosokawa, T.; Takai, H.; Shigenobu, S.; Nikoh, N.; Fukatsu, T.
10.1101/2024.08.16.608268 — evolutionary biology — Posted on 2024-08-17
2548 Phenotypic divergence associated with genomic changes suggest local adaptation in obligate asexuals
Karapli-Petritsopoulou, A.; Heckelmann, J. J.; Anderson, N. J.; Franzenburg, S.; Frisch, D.
10.1101/2024.08.15.608098 — evolutionary biology — Posted on 2024-08-17
2551 The level of HAND1 controls the specification of multipotent cardiac and extraembryonic progenitors
Lynch, A. T.; Phillips, N.; Douglas, M.; Dorgnach, M.; Lin, I.-H.; Adamson, A. D.; Darieva, Z.; Whittle, J.; Hanley, N. A.; Bobola, N.; Birket, M. J.
10.1101/2024.08.15.607916 — developmental biology — Posted on 2024-08-17
2552 The Changing Immune Landscape of Innate-like T Cells and Innate Cells Throughout Life
Taheri, M.; Menne, C.; Anderson, J.; Li, S.; Berzins, S. P.; Licciardi, P. V.; Ashhurst, T. M.; Jalali, S.; Pellicci, D. G.
10.1101/2024.08.14.608020 — immunology — Posted on 2024-08-17
2553 Quantitative 3D histochemistry reveals region-specific amyloid-β reduction by the antidiabetic drug netoglitazone
Catto, F.; Dadgar-Kiani, E.; Kirschenbaum, D.; Economides, A. E.; Reuss, A. M.; Trevisan, C.; Caredio, D.; Mirzet, D.; Frick, L.; Weber-Stadlbauer, U.; Litvinov, S.; Koumoutsakos, P.; Hyung Lee, J.; Aguzzi, A.
10.1101/2024.08.15.608042 — neuroscience — Posted on 2024-08-17
2554 The OMG dataset: An Open MetaGenomic corpus for mixed-modality genomic language modeling
Cornman, A.; West-Roberts, J.; Camargo, A. P.; Roux, S.; Beracochea, M.; Mirdita, M.; Ovchinnikov, S.; Hwang, Y.
10.1101/2024.08.14.607850 — systems biology — Posted on 2024-08-17
2555 Protein overabundance is driven by growth robustness
Choi, H. K.; Lo, T. W.; Cutler, K. J.; Huang, D.; Will, W. R.; Wiggins, P. A.
10.1101/2024.08.14.607847 — systems biology — Posted on 2024-08-17
2558 Loss of cped1 does not affect bone and lean mass in zebrafish
Alvarado, K.; Tang, W. J.; Watson, C. J.; Ahmed, A. R.; Gomez, A. E.; Donaka, R.; Amemiya, C. T.; Karasik, D.; Hsu, Y.-H.; Kwon, R. Y.
10.1101/2024.07.10.601974 — genetics — Posted on 2024-08-17
2559 A Sox2 Enhancer Cluster Regulates Region-Specific Neural Fates from Mouse Embryonic Stem Cells
Tobias, I. C.; Moorthy, S. D.; Shchuka, V. M.; Langroudi, L.; Cherednychenko, M.; Gillespie, Z. E.; Duncan, A. G.; Tian, R.; Gajewska, N. A.; Di Roberto, R. B.; Mitchell, J. A.
10.1101/2023.11.09.566464 — genetics — Posted on 2024-08-17
2561 Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females
Shain, A.; Savko, C.; Rokaw, S.; Jaafar, F.; Rieder, A.; Wright, M. K.; Phillips, J. A.; Konja, N.; Michael, S.; Mathews, H.; Jerjees, G.; Bailey, B.; Sussman, M.
10.1101/2024.08.01.606074 — molecular biology — Posted on 2024-08-17
2562 Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages
Winnicki, A. C.; King, C. L.; Bosch, J.; Malachin, A. N.; Carias, L. L.; Skomorovska-Prokvolit, Y.; Tham, W.-H.; Dietrich, M. H.; Popovici, J.; Roobsoong, W.; Beeson, J. G.; Sattabongkot, J.; Yeoh, L. M.; Opi, D. H.; Feufack-Donfack, L. B.; Orban, A.; Drago, C. L.; McLaine, O. S.; Redinger, K. R.; Jung, N. C.; Baldor, L.; Kirtley, P.; Neilsen, K.; Aleshnick, M.; Zanghi, G.; Rezakhani, N.; Vaughan, A. M.; Wilder, B. K.
10.1101/2024.02.07.579302 — immunology — Posted on 2024-08-17
2563 Novel tau filament folds in individuals with MAPT mutations P301L and P301T
Schweighauser, M.; Shi, Y.; Murzin, A. G.; Garringer, H. J.; Vidal, R.; Murrell, J. R.; Erro, M. E.; Seelaar, H.; Ferrer, I.; van Swieten, J. C.; Ghetti, B.; Scheres, S. H.; Goedert, M.
10.1101/2024.08.15.608062 — neuroscience — Posted on 2024-08-17
2564 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making
Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.
10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-08-17
2565 Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same construct.
de Guglielmo, G.; Carrette, L.; Kallupi, M.; Brennan, M.; Boomhower, B.; Maturin, L.; Conlisk, D.; Sedighim, S.; Tieu, L.; Fannon, M.; Martinez, A. R.; Velarde, N.; Othman, D.; Sichel, B.; Ramboger, J.; Lau, J.; Kononoff, J.; Kimbrough, A.; Simpson, S.; Smith, L.; Shankar, K.; Sneddon, E. A.; Bonnet-Zahedi, S.; Avelar, A.; Plasil, S. L.; Mosquera, J.; Crook, C.; Chun, L.; Vang, A.; Milan, K.; Schweitzer, P.; Lin, B.; Peng, B.; Chitre, A.; Polleskaya, O.; Woods, L. S.; Palmer, A. A.; George, O.
10.1101/2021.07.22.453410 — neuroscience — Posted on 2024-08-17
2566 Multimodal neural correlates of childhood psychopathology
Royer, J.; Kebets, V.; Piguet, C.; Chen, J.; Ooi, L. Q. R.; Kirschner, M.; Siffredi, V.; Misic, B.; Yeo, B. T. T.; Bernhardt, B.
10.1101/2023.03.02.530821 — neuroscience — Posted on 2024-08-17
2567 The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer
Souto, E. P.; Gong, P.; Landua, J. D.; Srinivasan, R. R.; Ganesan, A.; Dobrolecki, L. E.; Purdy, S. C.; Pan, X.; Zeosky, M.; Chung, A.; Yi, S. S.; Ford, H. L.; Lewis, M. T.
10.1101/2023.09.15.557958 — cancer biology — Posted on 2024-08-17
2574 REverse transcriptase ACTivity (REACT) assay for point-of-care measurement of established and emerging antiretrovirals for HIV treatment and prevention
Brainerd, C.; Singh, M. A.; Tatka, J.; Craig, C.; Gilligan-Steinberg, S.; Panpradist, N.; Chang, M. M.; Lutz, B.; Olanrewaju, A. O.
10.1101/2024.08.13.607804 — bioengineering — Posted on 2024-08-17
2575 Relationships of hematocrit concentration with dementia from a multiethnic population-based study
Roh, D. J.; Liu, M.; Strobino, K.; Assuras, S.; Guzman, V. A.; Levin, B.; Spitalnik, S.; Rundek, T.; Wright, C. B.; Elkind, M. S. V.; Gutierrez, J.
10.1101/2024.08.15.608190 — neuroscience — Posted on 2024-08-17
2576 Toss GERALT into chloroplast to make it green: a new regulator of chloroplast biogenesis and chlorophyll biosynthesis
Banas, A. K.; Grzyb, J.; Zglobicki, P.; Pacak, A.; Mysliwa-Kurdziel, B.; Leja, K.; Kozieradzka-Kiszkurno, M.; Klodawska, K.; Konieczny, R.; Pilarska, M.; Niewiadomska, E.; Bazant, A.; Szewc, L.; Kowalska, E. B.; Strzalka, W.
10.1101/2024.08.16.608208 — plant biology — Posted on 2024-08-17
2577 Early atrial remodelling drives arrhythmia in Fabry Disease
Roy, A.; O'Shea, C.; Dasi, A.; Patel, L.; CUMBERLAND, M.; NIEVES, D.; Canagarajah, H. S.; THOMPSON, S.; AZAD, A.; Price, A. M.; HALL, C.; Alvior, A. M. B.; RATH, P.; DAVIES, B.; Rodriguez, B.; Holmes, A. P.; Pavlovic, D.; Townend, J. N.; Geberhiwot, T.; GEHMLICH, K.; Steeds, R. P.
10.1101/2024.08.13.607853 — pathology — Posted on 2024-08-17
2578 Single-cell imaging of the lytic phage life cycle in bacteria
Wedd, C.; Yunusov, T.; Smith, A.; Li, R.; Hardo, G.; Hunter, M.; Majed, R.; Fusco, D.; Bakshi, S.
10.1101/2024.04.11.588870 — microbiology — Posted on 2024-08-17
2581 KS-WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates
Boyd-Shiwarski, C. R.; Beacham, R. T.; Lashway, J. A.; Querry, K. E.; Griffiths, S. E.; Shiwarski, D. J.; Knoell, S. A.; Nguyen, N. H.; Nkashama, L. J.; Valladares, M. N.; Bandaru, A.; Marciszyn, A. L.; Rodan, A. R.; Huang, C.-L.; Stocker, S. D.; Kashlan, O. B.; Subramanya, A. R.
10.1101/2021.03.12.435046 — physiology — Posted on 2024-08-17
2582 The Lactate Receptor GPR81 is a Mechanism of Leukemia-Associated Macrophage Polarization in the Bone Marrow Microenvironment
Soto, C. A.; Lesch, M. L.; Becker, J. L.; Sharipol, A.; Khan, A.; Shafer, X. L.; Becker, M. W.; Munger, J. C.; Frisch, B. J.
10.1101/2023.11.13.566874 — pathology — Posted on 2024-08-17
2585 Dissociable patterns of dopamine dynamics and causal contributions to stimulus-response behaviors across striatal subregions.
Princz-Lebel, O.; Skirzewski, M.; Rai, H.; Panjwani, S.; Chu, A.; Lemieux, C. A.; Palmer, D.; Machado, M. M. F.; Prado, V. F.; Prado, M. A. M.; Saksida, L. M.; Bussey, T. J.
10.1101/2024.08.16.608313 — animal behavior and cognition — Posted on 2024-08-17
2588 Negative regulation of APC/C activation by MAPK-mediated attenuation of Cdc20Slp1 under stress
Sun, L.; Chen, X.; Song, C.; Shi, W.; Liu, L.; Bai, S.; Wang, X.; Chen, J.; Jiang, C.; Wang, S.-m.; Luo, Z.-q.; Wang, R.; Wang, Y.; Jin, Q.-w.
10.1101/2024.04.02.587770 — cell biology — Posted on 2024-08-17
2589 Surface exclusion of IncC conjugative plasmids and their relatives
Rivard, N.; Humbert, M.; Huguet, K. T.; Fauconnier, A.; Perez Bucio, C.; Quirion, E.; Burrus, V.
10.1101/2023.05.15.540745 — microbiology — Posted on 2024-08-16
2591 Assessing white matter plasticity in a randomized controlled trial of early literacy training in preschoolers
Caffarra, S.; Karipidis, I. I.; Kruper, J.; Kubota, E.; Richie-Halford, A.; Takada, M.; Rokem, A.; Yeatman, J. D.
10.1101/2024.08.16.608210 — neuroscience — Posted on 2024-08-16
2592 Deficiency of Orexin Receptor Type 1 in Dopaminergic Neurons Increases Novelty-Induced Locomotion and Exploration
Xiao, X.; Yeghiazaryan, G.; Eggersmann, F.; Cremer, A. L.; Backes, H.; Kloppenburg, P.; Hausen, A. C.
10.1101/2023.08.06.552140 — neuroscience — Posted on 2024-08-16
2597 Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions
Campos-Leon, K.; Ferguson, J.; Gunther, T.; Wood, C. D.; Wingett, S.; Pekel, S.; Varghese, C. S.; Varnai, C.; West, M.; Beggs, A.; Grundhoff, A.; Noyvert, B.; Roberts, S.; Parish, J. L.
10.1101/2024.08.16.608206 — microbiology — Posted on 2024-08-16
2599 Temporal and spatial niche partitioning in a retrotransposon community of the Drosophila genome
Varoqui, M.; Mohamed, M.; Mugat, B.; Gourion, D.; Lemoine, M.; Pelisson, A.; Grimaud, C.; Chambeyron, S.
10.1101/2024.08.14.607943 — genomics — Posted on 2024-08-16
2600 Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans
Huang, J.; Larmore, C. J.; Priest, S. J.; Xu, Z.; Dietrich, F. S.; Yadav, V.; Magwene, P. M.; Sun, S.; Heitman, J.
10.1101/2024.08.15.608186 — genetics — Posted on 2024-08-16
2601 The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development.
Finer, G.; Khan, M. D.; Zhou, Y.; Gadhvi, G.; Yacu, G. S.; Park, J.-S.; Gomez, R. A.; Sequeira-Lopez, M. L.; Quaggin, S. E.; Winter, D. R.
10.1101/2024.08.14.607910 — developmental biology — Posted on 2024-08-16
2602 Semaglutide Improves Myocardial Perfusion and Performance in a Large Animal Model of Coronary Artery Disease
Stone, C.; Harris, D. D.; Broadwin, M.; Kanuparthy, M.; Nho, J.-W.; Yalamanchili, K.; Hamze, J.; Abid, M. R.; Sellke, F. W.
10.1101/2024.08.15.608191 — molecular biology — Posted on 2024-08-16
2603 Ribosomal RNA transcription governs splicing through ribosomal protein RPL22
Fan, W.; Liu, H.; Stachelek, G. C.; Begum, A.; Davis, C. E.; Dorado, T. E.; Ernst, G.; Reinhold, W. C.; Ozbek, B.; Zheng, Q.; Marzo, A. M. D.; Rajeshkumar, N. V.; Barrow, J. C.; Laiho, M.
10.1101/2024.08.15.608201 — molecular biology — Posted on 2024-08-16
2604 Protective threshold of a potent neutralizing Zika virus monoclonal antibody in rhesus macaques
Nkolola, J.; Hope, D.; Guan, R.; Colarusso, A.; Aid, M.; Carnahan, R.; Crowe, J. E.; Barouch, D. H.
10.1101/2024.08.16.608231 — microbiology — Posted on 2024-08-16
2605 Genomic analysis of antimicrobial resistant Escherichia coli isolated from manure and manured agricultural grasslands
Tyrrell, C.; Burgess, C. M.; Brennan, F.; Muenzenmaier, D.; Drissner, D.; Leigh, R. J.; Walsh, F.
10.1101/2024.08.16.608224 — microbiology — Posted on 2024-08-16
2610 3D Microphysiological Tumor Model for Dual-Targeting CAR T Cell Immunotherapy
PENG, X.; Janicijevic, Z.; Loureiro, L. R.; Hoffmann, L.; Lee, P. S.; Cela, I.; Kruppke, B.; Kegler, A.; Feldmann, A.; Bachmann, M.; Baraban, L.
10.1101/2024.08.16.608227 — bioengineering — Posted on 2024-08-16
2611 Genomic analyses identify 15 susceptibility loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally-occurring canine model of gastric cancer
Cook, S. R.; Hugen, S.; Hayward, J. J.; Famula, T. R.; Belanger, J. M.; McNiel, E.; Fieten, H.; Oberbauer, A. M.; Leegwater, P. A.; Ostrander, E. A.; Mandigers, P. J.; Evans, J. M.
10.1101/2024.08.14.604426 — genomics — Posted on 2024-08-16
2612 An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish
Carrothers, S.; Trevisan, R.; Jayasundara, N.; Pelletier, N.; Weeks, E.; Meyer, J. N.; Di Giulio, R. T.; Weinhouse, C.
10.1101/2024.08.14.607951 — genomics — Posted on 2024-08-16
2613 Comprehensive double-mutant analysis of the Bacillus subtilis envelope using double-CRISPRi
Koo, B.-M.; Todor, H.; Sun, J.; van Gestel, J.; Hawkins, J. S.; Hearne, C. C.; Banta, A. B.; Huang, K. C.; Peters, J. M.; Gross, C. A.
10.1101/2024.08.14.608006 — genomics — Posted on 2024-08-16
2614 EnteroBase in 2025: exploring the genomic epidemiology of bacterial pathogens
Dyer, N. P.; Pauker, B.; Baxter, L.; Gupta, A.; Bunk, B.; Overmann, J.; Diricks, M.; Dreyer, V.; Niemann, S.; Holt, K.; Rahman, M.; Brown, P. E.; Stark, R.; Zhou, Z.; Ott, S.; Nubel, U.
10.1101/2024.08.15.608032 — genomics — Posted on 2024-08-16
2615 Mutations in ErbB2 accumulating in the male germline measured by error-corrected sequencing
Yasari, A.; Heinzl, M.; Mair, T.; Karimian, T.; Moukbel, S. A.; Hartl, I.; Betancourt, A. J.; Lanzerstorfer, P.; Tiemann-Boege, I.
10.1101/2024.08.14.607923 — genetics — Posted on 2024-08-16
2617 MYH11 rare variant augments aortic growth and induces cardiac hypertrophy and heart failure with pressure overload
Zhou, Z.; Hughes, K.; Saif, N.; Kim, H.; Massett, M. P.; Zheng, M.; Cecchi, A. C.; Guo, D.; Murdock, D. R.; Pan, P.; Clinton, J. S.; Wang, J.; Greally, J. M.; Milewicz, D. M.
10.1101/2024.08.15.608063 — genetics — Posted on 2024-08-16
2618 S-RNase Evolution in Self-Incompatibility: Phylogenomic Insights into Synteny with S-Like Genes
Liu, Y.; Zhang, Y.; Han, S.; Guo, B.-C.; Liang, J.; Yu, Z.; Yang, F.; Sun, Y.; Xue, J.; Lin, Z.; Schranz, M. E.; Guan, C.; Ma, F.; Zhao, T.
10.1101/2024.08.14.607955 — evolutionary biology — Posted on 2024-08-16
2620 Ultrahigh-throughput discovery of modified aptamers as specific and potent enzyme inhibitors
Husser, C.; Hoetzel, J.; Cubi, R.; Lebars, I.; Kraus, L.; Di Primo, C.; Baudrey, S.; Proschak, E.; Kieffer, B.; Suess, B.; Ryckelynck, M.
10.1101/2024.08.16.608213 — molecular biology — Posted on 2024-08-16
2625 EEG source imaging technique to investigate sleep oscillations for simultaneous EEG-fMRI
Uji, M.; Jegou, A.; Cross, N. E.; Pomares, F. B.; Perrault, A. A.; Nguyen, A.; Aydin, U.; Lee, K.; Abdallah, C.; Frauscher, B.; Lina, J.-M.; Dang-Vu, T. T.; Grova, C.
10.1101/2024.08.13.607843 — neuroscience — Posted on 2024-08-16
2626 AMH regulates ovary size by counteracting ovarian follicle cluster effects.
Lim, C.; Yiew, L.; Anderson, N. J.; Smith, P.; Quirke, L.; Carne, A.; Sarma, U.; Rose, R.; Nicholson, M.; Jasoni, C. L.; Liu, P.; Petrich, S.; Juengel, J.; Pankhurst, M. W.
10.1101/2024.08.15.607694 — physiology — Posted on 2024-08-16
2631 High-fat diet exacerbates the loss of bone fracture toughness in aging for C57BL/6JN mice
Brown, K. C.; Vahidi, G.; Hislop, B. D.; Moody, M. C.; Watson, S.; Welhaven, H. D.; Behzad, R.; Paton, K.; Karim, L.; June, R. K.; Martin, S.; Heveran, C. M.
10.1101/2024.08.13.607633 — bioengineering — Posted on 2024-08-16
2632 Neuronal progenitors suffer genotoxic stress in the Drosophila clock mutant per0.
Colonna Romano, N.; Marchetti, M.; Marangoni, A.; Leo, L.; Retrosi, D.; Rosato, E.; Fanti, L.
10.1101/2024.08.13.607601 — genetics — Posted on 2024-08-16
2633 Mitochondrial calcium uniporter regulates human fibroblast-like synoviocytes invasion via altering mitochondrial dynamics and dictates rheumatoid arthritis pathogenesis
Promila, L.; Sarkar, K.; Guleria, S.; Rathore, M.; Singh, N. C.; Khan, S.; Tomar, M. S.; Ammanathan, V.; Barthwal, M. K.; Kumaravelu, J.; Shrivastava, A.; Mitra, K.; Guha, R.; Aggarwal, A.; Lahiri, A.
10.1101/2024.08.13.607857 — immunology — Posted on 2024-08-16
2635 The ageing stopping network: Regional and network changes in the IFG, preSMA, and STN across the adult lifespan
Kemp, S. A.; Bazin, P.-L.; Miletic, S.; Boag, R. J.; Keuken, M.; Hinder, M. R.; Forstmann, B.
10.1101/2024.08.13.607702 — neuroscience — Posted on 2024-08-16
2637 Network models incorporating chloride dynamics predict optimal strategies for terminating status epilepticus
Currin, C. B.; Burman, R. J.; Fedele, T.; Ramantani, G.; Rosch, R. E.; Sprekeler, H.; Raimondo, J. V.
10.1101/2024.08.13.607480 — neuroscience — Posted on 2024-08-16
2639 Microbial reaction rate estimation using proteins and proteomes
McCain, J. S. P.; Britten, G. L.; Hackett, S. R.; Follows, M. J.; Li, G.-W.
10.1101/2024.08.13.607198 — systems biology — Posted on 2024-08-16
2642 SynDRep: A Knowledge Graph-Enhanced Tool based on Synergistic Partner Prediction for Drug Repurposing
Shalaby, K. S.; Rao, S. G.; Schultz, B.; Hofmann-Apitius, M.; Tom Kodamullil, A.; Bharadhwaj, V. S.
10.1101/2024.08.13.607713 — bioinformatics — Posted on 2024-08-16
2643 Longitudinal metabolomics data analysis informed bymechanistic models
Li, L.; Hoefsloot, H. C.; Bakker, B. M.; Horner, D.; Rasmussen, M. A.; Smilde, A.; Acar, E.
10.1101/2024.08.13.607724 — bioinformatics — Posted on 2024-08-16
2646 Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane
Sarikhani, E.; Patel, V.; Li, Z.; Meganathan, D. P.; Rahmani, K.; Sadr, L.; Hosseini, R.; Visda, D.; Shukla, S.; Naghsh-Nilchi, H.; Balaji, A.; McMahon, G.; Chen, S.; Schoneberg, J.; McHugh, C. A.; Shi, L.; Jahed, Z.
10.1101/2024.08.13.605467 — bioengineering — Posted on 2024-08-16
2647 Exacerbation of influenza virus induced lung injury by alveolar macrophages and its suppression by pyroptosis blockade in a human lung alveolus chip
Man, Y.; Zhai, Y.; Jiang, A.; Bai, H.; Gulati, A.; Plebani, R.; Mannix, R. J.; Merry, G. E.; Goyal, G.; Belgur, C.; Hall, S. R. R.; Ingber, D. E.
10.1101/2024.08.13.607799 — bioengineering — Posted on 2024-08-16
2648 When monkeys meet an ANYmal robot in the wild
Canteloup, C.; Lee, J.; Zimmermann, S.; Alvino, M.; Montenegro, M.; Hutter, M.; van de Waal, E.
10.1101/2024.08.13.607714 — animal behavior and cognition — Posted on 2024-08-16
2650 Differences in maternal diet fiber content influence patterns of gene expression and chromatin accessibility in fetuses and piglets
Chalabi, S.; Loonen, L.; Boekhorst, J.; Li, H.; Fang, L.; Harrison, P. W.; Lakhal, W.; Lluch, J.; Sokolov, A.; Djebali, S.; Rau, A.; Giuffra, E.; Wells, J.
10.1101/2024.08.13.607725 — genomics — Posted on 2024-08-16
2651 Allopolyploidy expanded gene content but not pangenomic variation in the hexaploid oilseed Camelina sativa
Bird, K. A.; Brock, J. R.; Grabowski, P. P.; Harder, A. M.; Shu, S.; Barry, K.; Boston, L.; Daum, C.; Guo, J.; Lipzen, A.; Walstead, R.; Grimwood, J.; Schmutz, J.; Lu, C.; Edger, P. P.; Lovell, J. T.; Kliebenstein, D. J.
10.1101/2024.08.13.607619 — genomics — Posted on 2024-08-16
2653 Eomes directs the formation of spatially and functionally diverse extra-embryonic hematovascular tissues
Theeuwes, B.; Harland, L. T.; Bisia, A.; Costello, I.; Ton, M.-L.; Lohoff, T.; Clark, S. J.; Argelaguet, R.; Wilson, N. K.; Reik, W.; Bikoff, E.; Robertson, E. J.; Gottgens, B.
10.1101/2024.08.13.607790 — developmental biology — Posted on 2024-08-16
2654 Targeting Interferon-Driven Inflammatory Memory Prevents Epigenetic Evolution of Cancer Immunotherapy Resistance
Qiu, J.; Ye, D.; Chen, X. E.; Dangle, N.; Yoshor, B.; Zhang, T.; Shao, Y.; Nallamala, V. C.; Wang, S.; Ren, D.; Xu, Y.; Chen, J.; Zhang, N. R.; Shi, J.; Greenberg, R. A.; Minn, A. J.
10.1101/2024.08.13.607862 — immunology — Posted on 2024-08-16
2655 Single-cell analysis identifies distinct CD4+ T cells associated with the pathobiology of pediatric obesity-related asthma
Thompson, D.; Wabara, Y.; Duran, S.; Reichenbach, A.; Chen, L.; Collado, K.; Yon, C.; Greally, J. M.; Rastogi, D.
10.1101/2024.08.13.607447 — immunology — Posted on 2024-08-16
2656 Parvalbumin expression identifies subicular principal cells with high projection specificity
Baccini, G.; Foggetti, A.; Wernet, N.; Engelhardt, K. A.; Kronenbitter, K.; Michels, J.; Kulik, A.; Wozny, C.; Wulff, P.
10.1101/2024.08.13.606964 — neuroscience — Posted on 2024-08-16
2659 Age-dependent cortical overconnectivity revers under anesthesia in Shank3 mice
Montagni, E.; Ambrosone, M.; Martello, A.; Curti, L.; Baroncelli, L.; Mannaioni, G.; Pavone, F.; Masi, A.; Allegra Mascaro, A. L.
10.1101/2024.08.13.607775 — neuroscience — Posted on 2024-08-16
2666 Development of a preclinical screening platform for clinically relevant therapy of Dravet syndrome
Mensah, J. A.; Thomson, K. E.; Huff, J. L.; Freeman, T.; Reilly, C. A.; Rower, J. E.; Metcalf, C. S.; Wilcox, K. S.
10.1101/2024.08.13.607806 — pharmacology and toxicology — Posted on 2024-08-16
2668 Silver nanoparticle induced immunogenic cell death can improve immunotherapy
Sargsian, A.; Koutsoumpou, X.; Girmatsion, H.; Buttiens, K.; Rios Luci, C.; Soenen, S. J.; Manshian, B. B.
10.1101/2024.08.13.607617 — cancer biology — Posted on 2024-08-16
2669 Automated microinjection for zebrafish xenograft models
Ding, Y.; van der Kolk, K.-J.; van der Ent, W.; Scotto di Mase, M.; Kowald, S.; Huizing, J.; Vidal Teuton, J. M.; Mishra, G.; Kempers, M.; Almter, R.; Munier, L.; Di Donato, V.; Dyballa, S.; ten Dijke, P.; Esguerra, C. V.; Jensen, L. D.; de Sonneville, J.
10.1101/2024.08.13.607596 — cancer biology — Posted on 2024-08-16
2670 Discovery of Z1362873773: A Novel Fascin Inhibitor from a Large Chemical Library for Colorectal Cancer
Rodriguez-Martinez, A.; Giraldo-Ruiz, L.; Ramos, M. C.; Luque, I.; Ribeiro, D.; Postigo-Corrales, F.; Alburquerque-Gonzalez, B.; Montoro-Garcia, S.; Arroyo-Rodriguez, A. B.; Conesa-Zamora, P.; Hurtado, A. M.; Luengo-Gil, G.; Perez-Sanchez, H.
10.1101/2024.08.13.606007 — cancer biology — Posted on 2024-08-16
2671 VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradation
Mangano, K.; Guenette, R. G.; Hill, S.; Li, S.; Yang, S. W.; Ashton, K. S.; Potts, P. R.
10.1101/2024.08.13.607762 — cancer biology — Posted on 2024-08-16
2674 Comparative Analysis of Polysaccharide and Cell Wall Structure in Aspergillus nidulans and Aspergillus fumigatus by Solid-State NMR
Gautam, I.; Yarava, J. R.; Xu, Y.; Li, R.; Scott, F. J.; Mentink-Vigier, F.; Momany, M.; Latge, J.-P.; Wang, T.
10.1101/2024.08.13.607833 — biophysics — Posted on 2024-08-16
2677 A quantitative pipeline for whole-mount deep imaging and multiscale analysis of gastruloids
Gros, A.; Vanaret, J.; Dunsing-Eichenauer, V.; Rostan, A.; Roudot, P.; Lenne, P.-F.; Guignard, L.; Tlili, S.
10.1101/2024.08.13.607832 — biophysics — Posted on 2024-08-16
2678 Genetic differentiation and adaptive evolution of buff-tailed bumblebees in Asia
Su, L.; Din, L.; Williams, P. H.; Liu, Y.; Wang, R.; Dai, X.; Zhao, S.; Fu, H.; Zhao, X.; Wang, Q.; Li, Y.; Sang, H.; Waterhouse, R. M.; Zhai, Y.; Sun, C.
10.1101/2024.08.13.607144 — bioinformatics — Posted on 2024-08-16
2683 In silico studies provide new structural insights into trans-dimerization of β1 and β2 subunits of the Na+,K+-ATPase
Ramirez Salinas, G.; Rosas-Trigueros, J. L.; Sosa Huerta, C.; Shoshani, L.; Martinez Archundia, M. T.
10.1101/2024.08.13.607722 — bioinformatics — Posted on 2024-08-16
2687 Overcoming fixation and permeabilization challenges in flow cytometry by optical barcoding and multi-pass acquisition
Fahlberg, M. D.; Forward, S.; Assita, E. R.; Mazzola, M.; Kiem, A.; Handley, M.; Yun, S. H.; Kwok, S. J.
10.1101/2024.08.13.607771 — bioengineering — Posted on 2024-08-16
2688 Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data
Simmons, S. K.; Adiconis, X.; Haywood, N.; Parker, J.; Lin, Z.; Liao, Z.; Tuncali, I.; Al'Khafaji, A.; Shin, A.; Jagadeesh, K.; Gosik, K.; Gatzen, M.; Smith, J. T.; El Kodsi, D. N.; Kuras, Y.; Baecher-Allan, C.; Serrano, G. E.; Beach, T. G.; Garimella, K.; Rozenblatt-Rosen, O.; Regev, A.; Dong, X.; Scherzer, C.; Levin, J. Z.
10.1101/2024.08.13.607784 — genomics — Posted on 2024-08-16
2689 Rhizosphere Microbiome Influence on Tomato Growth under Low-Nutrient Settings
Mejia, G.; Jara-Servin, A.; Romero-Chora, L.; Hernandez-Alvarez, C.; Peimbert, M.; Cruz-Ortega, R.; Alcaraz, L. D.
10.1101/2024.08.13.607683 — genomics — Posted on 2024-08-16
2690 Predicting the global economic costs of biological invasions by tetrapods
Bodey, T.; Cuthbert, R.; Diagne, C.; Marino, C.; Turbelin, A.; Angulo, E.; Fantle-Lepczyk, J.; Pincheira-Donoso, D.; Courchamp, F.; Hudgins, E.
10.1101/2024.08.15.606318 — ecology — Posted on 2024-08-16
2693 Distinct bandwidths of orexin neuron activity independently encode body movement and metabolic state
Tesmer, A. L.; Viskaitis, P.; Donegan, D.; Bracey, E.; Grujic, N.; Patriarchi, T.; Peleg-Raibstein, D.; Burdakov, D.
10.1101/2024.08.13.607750 — neuroscience — Posted on 2024-08-16
2698 Co-release of GABA and ACh from medial olivocochlear neurons fine tunes cochlear efferent inhibition
Castagnola, T.; Castagna, V. C.; Kitcher, S.; Torres Cadenas, L.; Di Guilmi, M. N.; Gomez Casati, M. E.; Buonfiglio, P. I.; Dalamon, V.; Katz, E.; Elgoyhen, A. B.; Weisz, C.; Goutman, J.; Wedemeyer, C.
10.1101/2024.08.12.607644 — physiology — Posted on 2024-08-16
2702 Enhanced Suppression of Stenotrophomonas maltophilia by a Three-Phage Cocktail: Genomic Insights and Kinetic Profiling
Monsibais, A. N.; Tea, O.; Ghatbale, P.; Phan, J.; Lam, K.; Paulson, M.; Tran, N.; Suder, D. S.; Blanc, A.; Samillano, C.; Suh, J.; Dunham, S. J. B.; Gonen, S.; Pride, D. T.; Whiteson, K.
10.1101/2024.08.14.607921 — microbiology — Posted on 2024-08-16
2703 Differential EBV protein-specific antibody response between responders and non-responders to EBVSTs immunotherapy
Sarathkumara, Y.; Van Bibber, N. W.; Liu, Z.; Heslop, H. E.; Rouce, R. H.; Coghill, A. E.; Rooney, C. M.; Proietti, C.; Doolan, D.
10.1101/2024.08.14.607997 — microbiology — Posted on 2024-08-16
2704 Imaging high-frequency voltage dynamics in multiple neuron classes of behaving mammals
Haziza, S.; Chrapkiewicz, R.; Zhang, Y.; Kruzhilin, V.; Li, J.; Li, J.; Delamare, G.; Swanson, R.; Buzsaki, G.; Kannan, M.; Vasan, G.; Lin, M. Z.; Zeng, H.; Daigle, T. L.; Schnitzer, M. J.
10.1101/2024.08.15.607428 — neuroscience — Posted on 2024-08-16
2707 Gray matter correlates of childhood maltreatment in the context of major depression: searching for replicability in a multi-cohort brain-wide association study of 3225 adults
Goltermann, J.; Winter, N. R.; Meinert, S.; Grotegerd, D.; Kraus, A.; Flinkenflügel, K.; Altegoer, L.; Krieger, J.; Leehr, E. J.; Böhnlein, J.; Bonnekoh, L. M.; Richter, M.; Hahn, T.; Fisch, L.; Gruber, M.; Hermesdorf, M.; Berger, K.; Arolt, V.; Brosch, K.; Stein, F.; Thomas-Odenthal, F.; Usemann, P.; Teutenberg, L.; Hammes, V.; Jamalabadai, H.; Alexander, N.; Straube, B.; Jansen, A.; Nenadic, I.; Kircher, T.; Opel, N.; Dannlowski, U.
10.1101/2024.08.15.608132 — neuroscience — Posted on 2024-08-16
2708 Low-pass nanopore sequencing for measurement of global methylation levels in plants
Liau, Y.; Whibley, A.; Hill, A. M.; Vanga, B. R.; Pither-Joyce, M.; Hilario, E.; Bailey, S.; Thomson, S.; Lizamore, D.
10.1101/2024.08.12.607255 — genomics — Posted on 2024-08-16
2709 Circulating extracellular microRNAs in the blood promote sociability in mice
Dohi, E.; Matoba, K.; Garcia, P. A.; Francis-Oliveira, J.; Anguiano, F.; Kochi, T.; Badrani, J. H.; See, J.; Ito, N.; Mitani, R.; Rose, I. V.; Choi, E. Y.; Imai, T.; Crossman, D. K.; Pletnikov, M. V.; Witwer, K. W.; Niwa, M.; Kano, S.
10.1101/2024.08.12.605506 — neuroscience — Posted on 2024-08-16
2712 ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses
Catanzaro, N.; Wu, Z.; Fan, C.; Schaefer, A.; Yount, B.; Bjorkman, P.; Baric, R. S.; Letko, M. C.
10.1101/2024.03.13.584892 — microbiology — Posted on 2024-08-16
2714 A common phthalate replacement disrupts ovarian function in young adult mice
Potts, C.; Harbolic, A.; Murphy, M.; Jojy, M.; Hanna, C.; Nadeem, M.; Alahmadi, H.; Martinez, S.; Warner, G. R.
10.1101/2024.08.14.607936 — pharmacology and toxicology — Posted on 2024-08-16
2715 A compact prism-based microscope for high sensitive measurements in fluid biopsy
Perego, L.; Dallari, C.; Falciani, C.; Pini, A.; Gardini, L.; Credi, C.; Pavone, F. S.
10.1101/2024.08.13.607708 — biophysics — Posted on 2024-08-16
2716 RAF inhibitors activate the integrated stress response by direct activation of GCN2
Gilley, R.; Kidger, A. M.; Neill, G.; Severson, P.; Byrne, D. P.; Kenneth, N. S.; Bollag, G.; Zhang, C.; de Oliveira, T. M.; Eyers, P.; Bayliss, R.; Masson, G. R.; Cook, S. J.
10.1101/2024.08.15.607884 — biochemistry — Posted on 2024-08-16
2719 Astrogliosis And Neuroinflammation Underlie Scoliosis Upon Cilia Dysfunction
Djebar, M.; Anselme, I.; Pezeron, G.; Bardet, P.-L.; Cantaut-Belarif, Y.; Eschstruth, A.; Lopez-Santos, D.; Le Ribeuz, H.; Jenett, A.; Khoury, H.; Veziers, J.; Parmentier, C.; Hirschler, A.; Carapito, C.; Bachmann-Gagescu, R.; Schneider-Maunoury, S.; Vesque, C.
10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-08-16
2723 Severe fire regimes decrease resilience of ectothermic populations
Sousa, H. C.; Malvasio, A.; Colli, G. R.; Salguero-Gomez, R. C.
10.1101/2023.06.25.546448 — ecology — Posted on 2024-08-16
2724 A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection
Fitzmeyer, E. A.; Dutt, T. S.; Pinaud, S.; Graham, B.; Gallichotte, E. N.; Hill, J. L.; Campbell, C.; Ogg, H.; Howick, V. M.; Lawniczak, M.; Osborne Nishimura, E.; Merkling, S. H.; Henao-Tamayo, M.; Ebel, G. D.
10.1101/2024.07.23.603613 — microbiology — Posted on 2024-08-16
2725 Fibroblastic FLT3L supports lymph node dendritic cells in the interfollicular niche
Lane, R. S.; Wu, S. Z.; Davidson, C.; Byrne, A.; Kayser, B.; Huang, H.; Williams, K.; Fernandez, M.; Jiang, J.; Zhang, J.; Asuncion, R.; Decalf, J.; Roose-Girma, M.; Lee, W.; McGinnis, L.; Warming, S.; Stephenson, W.; Rost, S.; Moussion, C.; Biancalani, T.; Muller, S.; Turley, S. J.
10.1101/2024.08.12.607692 — immunology — Posted on 2024-08-16
2726 Age-Related Differences in Human Cortical Microstructure Depend on the Distance to the Nearest Vein
Knoll, C.; Doehler, J.; Northall, A.; Schreiber, S.; Rotta, J.; Mattern, H.; Kuehn, E.
10.1101/2023.12.20.572529 — neuroscience — Posted on 2024-08-16
2727 Tunnelling nanotubules are druggable mediators of cancer-niche crosstalk.
Hockney, S.; Parker, J.; Tzivelekis, B.; Blair, H.; Dalgarno, K.; Pal, D.
10.1101/2023.06.20.545732 — cancer biology — Posted on 2024-08-16
2733 Morpho-physiological and transcriptomic responses of field pennycress to waterlogging
Combs-Giroir, R.; Shah, M.; Chhetri, H.; Morgan, M.; Prates, E. T.; Townsend, A.; Phippen, M. E.; Phippen, W. B.; Jacobson, D. A.; Gschwend, A. R.
10.1101/2024.08.15.608142 — plant biology — Posted on 2024-08-16
2734 Enhanced auxin signaling hub triggers root hair growth at moderate low temperature in Arabidopsis thaliana
Gabarain, V. B.; Nunez-Lillo, G.; Pencik, A.; Ibeas, M. A.; Pacheco, J. M.; Lopez, L. E.; Carignani, M.; Zhongtao, J.; Novak, O.; Giehl, R. F. H.; von Wiren, N.; Meneses, C.; Estevez, J.
10.1101/2024.08.15.608078 — plant biology — Posted on 2024-08-16
2738 Developmental stage determines the realized energy landscape for a flight specialist
Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J. S.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.
10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2024-08-16
2739 Failure to Resolve Inflammation Contributes to Juvenile-Onset Cardiomyopathy in a Mouse Model of Duchenne Muscular Dystrophy
Novak, J. S.; Lischin, A.; Uapinyoying, P.; Hindupur, R.; Moon, Y. J.; Bhattacharya, S.; Tiufekchiev, S.; Barone, V.; Mazala, D. A.; Gamu, I. H.; Walters, G.; Panchapakesan, K.; Jaiswal, J. K.
10.1101/2024.08.15.607998 — cell biology — Posted on 2024-08-15
2740 New imaging tools reveal live cellular collagen secretion, fibril dynamics and network organisation.
Kent, O.; Casey, E. R.; Brown, M.; Bell, S.; Ehrman, M. C.; Flagler, M. J.; Maatta, A.; Benham, A. M.; HAWKINS, T. J.
10.1101/2024.08.15.608104 — cell biology — Posted on 2024-08-15
2742 Discovery of embryonically derived bipotent endothelial-macrophage progenitor cells in postnatal aorta
Williamson, A. E.; Liyanage, S.; Hassanshahi, M.; Dona, M. S. I.; Toledo-Flores, D.; Tran, D. X. A.; Dimasi, C.; Schwarz, N.; Fernando, S.; Salagaras, T.; Long, A.; Kazenwadel, J.; Harvey, N. L.; Drummond, G. R.; Vinh, A.; Chandrakanthan, V.; Misra, A.; Neufeld, Z.; Tan, J. T. M.; Martelotto, L. G.; Polo, J. M.; Bonder, C. S.; Pinto, A. R.; Sharma, S.; Nicholls, S. J.; Bursill, C. A.; Psaltis, P. J.
10.1101/2021.10.18.464001 — cell biology — Posted on 2024-08-16
2743 Membrane tension regulation is required for wound repair
Raj, N.; Weiss, M.; Vos, B. E.; Weischer, S.; Brinkmann, F.; Betz, T.; Trappmann, B.; Gerke, V.
10.1101/2024.08.15.608096 — cell biology — Posted on 2024-08-16
2744 Serum Amyloid P Secreted by Bone Marrow Adipocytes Drives Skeletal Amyloidosis
Kumar, S.; Song, K.; Wang, J.; Baghel, M. S.; Wong, P.; Cao, X.; Wan, M.
10.1101/2024.08.15.608092 — cell biology — Posted on 2024-08-16
2748 Sequence action representations contextualize during rapid skill learning
Dash, D.; Iwane, F.; Hayward, W.; Salamanca-Giron, R.; Bonstrup, M.; Buch, E.; Cohen, L.
10.1101/2024.08.15.608189 — neuroscience — Posted on 2024-08-15
2749 Hemoglobin as a peroxidase and drug target for oxidative stress-related diseases
Won, W.; Lee, E. H.; Gotina, L.; Chun, H.; Park, U.; Lee, J.-H.; Kim, D.; Kim, T. Y.; Choi, J.; Kim, Y.; Park, S. J.; Bhalla, M.; Lim, J.; Park, J.-H.; Oh, S.-J.; Ryu, H.; Pae, A. N.; Park, K. D.; Lee, C. J.
10.1101/2024.05.21.594979 — neuroscience — Posted on 2024-08-16
2750 Modelling medulloblastoma pathogenesis and treatment in human cerebellar organoids.
Willott, T. O.; Nicholson, J. G.; Xiao, Y.; Ogunbiyi, O. K.; Mistry, T.; Zabet, N. R.; Merve, A.; Badodi, S.; Marino, S.
10.1101/2024.08.14.607977 — cancer biology — Posted on 2024-08-15
2752 Whole-brain dynamics of articulatory, acoustic and semantic speech representations
Verwoert, M.; Amigo-Vega, J.; Gao, Y.; Ottenhoff, M.; Kubben, P.; Herff, C.
10.1101/2024.08.15.608082 — neuroscience — Posted on 2024-08-15
2758 Ubiquitination mediates protein localization in RNA virus-infected cells
Shi, S.; Iesmantavicius, V.; Sabu, A. S.; Soneson, C.; Kohler, H.; Sanchez, J.; Ghosh, S.; Cao, C.; Huang, Y.; Matthias, G.; Yamauchi, Y.; Matthias, P.; Wang, L.
10.1101/2024.08.15.608034 — molecular biology — Posted on 2024-08-15
2761 Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription
Roberts, A. P. E.; Orr, A.; Iliev, V.; Orr, L.; McFarlane, S.; Yang, Z.; Epifano, I.; Loney, C.; Collados Rodriguez, M.; Cliffe, A. R.; Conn, K. L.; Boutell, C.
10.1101/2024.08.15.608064 — microbiology — Posted on 2024-08-15
2763 Allosteric Regulation of Pyruvate Kinase Enables Efficient and Robust Gluconeogenesis by Preventing Metabolic Conflicts and Carbon Overflow
She, F.; Anderson, B. W.; Khana, D. B.; Zhang, S.; Steinchen, W.; Fung, D. K. C.; Lucas, L. N.; Lesser, N. G.; Stevenson, D. M.; Astmann, T. J.; Bange, G.; van Pijkeren, J. P.; Amador-Noguez, D.; Wang, J. D.
10.1101/2024.08.15.607825 — microbiology — Posted on 2024-08-15
2765 T cells promote distinct transcriptional programs of cutaneous inflammatory disease in human skin structural cells
DeBerg, H. A.; Fahning, M. L.; Schlenker, J. D.; Schmitt, W. P.; Gratz, I. K.; Carlin, J. S.; Campbell, D. J.; Morawski, P. A.
10.1101/2024.07.31.606077 — immunology — Posted on 2024-08-15
2768 Rapid nongenomic estrogen signaling controls alcohol drinking behavior
Zallar, L. J.; Rivera-Irizarry, J. K.; Hamor, P. U.; Pigulevskiy, I.; Liu, D.; Welday, J. P.; Rico Rozo, A.-S.; Bender, R.; Asfouri, J.; Skelly, M. J.; Fecteau, K. M.; Hadley, C. K.; Levine, O. B.; Mehanna, H.; Nelson, S.; Miller, J.; Ghazal, P.; Bellotti, P.; Erikson, D. W.; Geri, J.; Pleil, K. E.
10.1101/2023.11.02.565358 — neuroscience — Posted on 2024-08-15
2769 Preclinical evaluation of the novel CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease
Zajicek, F.; Verhaeghe, J.; de Lombaerde, S.; Van Eetveldt, A.; Miranda, A.; Munoz-Sanjuan, I.; Dominguez, C.; Khetarpal, V.; Bard, J.; Liu, L.; Staelens, S.; Bertoglio, D.
10.1101/2024.05.16.594492 — neuroscience — Posted on 2024-08-15
2773 SARS-CoV-2 and Mycobacterium tuberculosis co-infection in vitro
Lucena, T. M. C. d.; Miranda, D. E. O.; Arcoverde, J. V. B.; Cavalcanti, M. S. B.; Rabello, M. C. d. S.; Silva, J. d. A.
10.1101/2024.08.14.607914 — cell biology — Posted on 2024-08-15
2774 Chemotherapy causes a reversible decrease in VMP1/MIR21 DNA methylation in granulocytes from breast cancer survivors
Abrahamsen, M.-L.; Jachowicz, Z.; Buch-Larsen, K.; Marina, D.; Andersson, M.; Schwarz, P.; Dela, F.; Gillberg, L.
10.1101/2024.08.15.608076 — molecular biology — Posted on 2024-08-15
2775 Emerging Clostridioides difficile ribotypes have divergent metabolic phenotypes
Midani, F. S.; Danhof, H. A.; Mathew, N.; Ardis, C. K.; Garey, K. W.; Spinler, J. K.; Britton, R. A.
10.1101/2024.08.15.608124 — microbiology — Posted on 2024-08-15
2776 Cappable-Seq reveals the transcriptional landscape of stress responses in the bacterial endosymbiont Wolbachia
Suliman, Y. M.; Li, Z.; Sinha, A.; Dyer, P. D.; Hartley, C. S.; Darby, A. C.; Carlow, C. K. S.; Makepeace, B. L.
10.1101/2024.08.15.608088 — microbiology — Posted on 2024-08-15
2777 A widespread hydrogenase drives fermentative growth of gut bacteria in healthy people
Welsh, C.; Cabotaje, P. R.; Marcelino, V. R.; Watts, T. D.; Kountz, D. J.; Gould, J. A.; Doan, N. Q.; Lingford, J. P.; Solari, J.; D'Adamo, G. L.; Huang, P.; Bong, N.; Gulliver, E. L.; Young, R. B.; Walter, K.; Wolf, P. G.; Ridlon, J. M.; Gaskins, H. R.; Giles, E. M.; Lyras, D.; Lappan, R.; Berggren, G.; Forster, S. C.; Greening, C.
10.1101/2024.08.15.608110 — microbiology — Posted on 2024-08-15
2778 Competition and Compromise between Exogenous Probiotics and Native Microbiota
Han, Z.; Sun, Z.; Zhao, Q.; Du, L.; Zhen, D.; Liu, X.; Jiang, S.; Liu, Y.-Y.; Zhang, J.
10.1101/2024.08.15.608074 — microbiology — Posted on 2024-08-15
2779 HSP90 interacts with VP37 to facilitate the cell-to-cell movement of broad bean wilt virus 2
Kim, M.-H.; Jang, S.-Y.; Choi, J.-S.; Kim, S.; Lee, Y.; Park, S.; Kwon, S.-J.; Seo, J.-K.
10.1101/2024.08.15.608091 — microbiology — Posted on 2024-08-15
2780 Viral and bacterial plant pathogens suppress antiviral defense against flaviviruses in their insect vectors
Larrea-Sarmiento, A. E.; Olmedo-Velarde, A.; West-Ortiz, M.; Stuehler, D.; Hosseinzadeh, S.; Coleman, A.; Preising, S.; Parker, G.; Fei, Z.; Heck, M. L.
10.1101/2024.08.15.608128 — microbiology — Posted on 2024-08-15
2781 Semi-Automatic Segmentation of Pseudomonas koreensis and Escherichia coli for Bacterial Growth Characterization
Alvarado-Ruiz, D. A.; Ordaz-Hernandez, K.; Diaz-Jiminez, L.; Lara-Cadena, G. L.; Gonzalez-Lopez, R.; Vargas-Gutierrez, G.; Castelan, M.
10.1101/2024.08.15.608040 — microbiology — Posted on 2024-08-15
2782 Human-derived microRNA 21 regulates indole and L-tryptophan biosynthesis transcripts in a prominent gut symbiont
Flanagan, K.; Gassner, K.; Lang, M.; Ozelyte, J.; Hausmann, B.; Crepaz, D.; Pjevac, P.; Gasche, C.; Berry, D.; Vesely, C.; Pereira, F. C.
10.1101/2024.08.15.608161 — microbiology — Posted on 2024-08-15
2783 Hatching of whipworm eggs induced by bacterial contact is serine-protease dependent
Goulding, D.; Tolley, C.; Mkandawire, T. T.; Doyle, S. R.; Hart, E.; Airs, P. M.; Grencis, R. K.; Berriman, M.; Duque-Correa, M. A.
10.1101/2024.08.15.608065 — microbiology — Posted on 2024-08-15
2784 Methanogenesis inhibition remodels microbial fermentation and stimulates acetogenesis in ruminants
Ni, G.; Walker, N.; Fischer, A.; Stemmler, R. T.; Schmidt, O.; Jain, S.; Jespersen, M.; Grinter, R.; Wang, M.; Pope, P. B.; Muller, V.; Watson, M.; Ver Loren van Themaat, E.; Kindermann, M.; Greening, C.
10.1101/2024.08.15.608071 — microbiology — Posted on 2024-08-15
2785 Coupling of secondary metabolite production in Bacillus subtilis
Dinesen, C.; Vertot, M.; Jarmusch, S. A.; Lozano-Andrade, C. N.; Andersen, A.; Kovacs, A. T.
10.1101/2024.08.15.608099 — microbiology — Posted on 2024-08-15
2787 Identification of biomarkers for COVID-19 associated secondary hemophagocytic lymphohistiocytosis
Canny, S. P.; Stanaway, I. B.; Holton, S. E.; Mitchem, M. A.; O'Rourke, A.; Pribitzer, S.; Baxter, S. K.; Wurfel, M. M.; Malhotra, U.; Buckner, J. H.; Bhatraju, P. K.; Morrell, E. D.; Speake, C.; Mikacenic, C.; Hamerman, J.
10.1101/2024.08.13.607855 — immunology — Posted on 2024-08-15
2790 PhOxi-seq detects enzyme-dependent m2G in multiple RNA types
Klimontova, M.; Chung, K. C. K.; Zhang, H.; Kouzarides, T.; Bannister, A. J.; Hili, R.
10.1101/2024.08.15.608094 — biochemistry — Posted on 2024-08-15
2791 Spatial mapping of immunosuppressive cancer-associated fibroblast gene signatures in H&E-stained images using additive multiple instance learning
Markey, M.; Kim, J.; Goldstein, Z.; Gerardin, Y.; Brosnan-Cashman, J.; Javed, S. A.; Juyal, D.; Padigela, H.; Yu, L.; Rahsepar, B.; Abel, J.; Hennek, S.; Khosla, A.; Taylor-Weiner, A.; Parmar, C.
10.1101/2024.08.12.607604 — cancer biology — Posted on 2024-08-15
2793 Open-source 3D printed manifolds for exposure studies using human airway epithelial cells
Singer, R.; Ball, E.; Milad, N.; Nguyen, J. P.; Cao, Q.; Selvaganapathy, P. R.; Zhang, B.; Dabaghi, M.; Satia, I.; Hirota, J. A.
10.1101/2024.08.12.607646 — bioengineering — Posted on 2024-08-15
2794 Revealing the Auxetic Behavior of Biomimetic Multi-material and Region-specific Nanofibrous Scaffolds via Synchrotron Multiscale Digital Volume Correlation: Innovative Building Blocks for the Enthesis Regeneration
Sensini, A.; Giacomini, F.; Stamati, O.; Lukic, B.; Villanova, J.; Proudhon, H.; Gille, M.; Birgani, Z. T.; Truckenmuller, R.; Tozzi, G.; van Griensven, M.; Moroni, L.
10.1101/2024.08.12.607645 — bioengineering — Posted on 2024-08-15
2795 The role of mitochondrial complex I in the proinflammatory response to polylactide implants
Maduka, C. V.; Makela, A. V.; Tundo, A.; Ural, E.; Stivers, K. B.; Alhaj, M.; Narayan, R.; Goodman, S. B.; Ashammakhi, N.; Elisseeff, J. H.; Hankenson, K. D.; Contag, C. H.
10.1101/2024.08.12.607680 — bioengineering — Posted on 2024-08-15
2800 A hollow fiber membrane-based liver organoid-on-a-chip model for examining drug metabolism and transport
Myszczyszyn, A.; Muench, A.; Lehmann, V.; Sinnige, T.; van Steenbeek, F. G.; Bouwmeester, M.; Samsom, R.-A.; Keuper-Navis, M.; van der Made, T. K.; Kogan, D.; Braem, S.; van der Laan, L. J. W.; Eslami Amirabadi, H.; van de Steeg, E.; Masereeuw, R.; Spee, B.
10.1101/2024.08.12.607504 — pharmacology and toxicology — Posted on 2024-08-15
2801 Dominant Malignant Clones Leverage Lineage Restricted Epigenomic Programs to Drive Ependymoma Development
Kardian, A.; Sun, H.; Ippagunta, S.; Laboe, N.; Chen, H.-C.; Emanus, E.; Varadharajan, S.; Zheng, T.; Holcomb, B.; Connelly, P.; Connelly, J. P.; Wang, M.; Lowe, K.; Pruett-Miller, S.; Bertrand, K. C.; Deneen, B.; Mack, S. C.
10.1101/2024.08.12.607603 — cancer biology — Posted on 2024-08-15
2803 Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating
Liu, P.; Pan, Y.; Chang, H.-C.; Fang, Y.; Xue, X.; Zou, J.; Toothaker, J. M.; Olaloye, O.; Santiago, E. G.; McCourt, B.; Mitsialis, V.; Presicce, P.; Kallapur, S. G.; Snapper, S. B.; Liu, J.-J.; Tseng, G.; Konnikova, L.; Liu, S.
10.1101/2024.08.12.607667 — bioinformatics — Posted on 2024-08-15
2805 Dose-Efficient Cryo-Electron Microscopy for Thick Samples using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single Particles
Yu, Y.; Spoth, K. A.; Colletta, M.; Nguyen, K. X.; Zeltmann, S. E.; Zhang, X. S.; Paraan, M.; Kopylov, M.; Dubbeldam, C.; Serwas, D.; Siems, H.; Muller, D. A.; Kourkoutis, L. F.
10.1101/2024.04.22.590491 — cell biology — Posted on 2024-08-15
2808 Patch-walking: Coordinated multi-pipette patch clamp for efficiently finding synaptic connections
Yip, M. C.; Gonzalez, M. M.; Lewallen, C. F.; Landry, C. R.; Kolb, I.; Yang, B.; Stoy, W. M.; Fong, M.-f.; Rowan, M. J.; Boyden, E. S.; Forest, C. R.
10.1101/2024.03.30.587445 — bioengineering — Posted on 2024-08-15
2809 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences
Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.
10.1101/2024.03.05.583455 — microbiology — Posted on 2024-08-15
2810 A Novel Human Extravascular Monocyte Subset with Antiviral Functions Is Crucial for Resolving Lung Tissue Infection
Kenney, D. J.; O'Connell, A. K.; Tseng, A. E.; Turcinovic, J.; Sheahan, M. L.; Nitido, A. D.; Montanaro, P.; Gertje, H. P.; Ericsson, M.; Connor, J. H.; Vrbanac, V.; Crossland, N. A.; Harly, C.; Balazs, A. B.; Douam, F.
10.1101/2024.03.08.583965 — immunology — Posted on 2024-08-15
2811 Hidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model
Cassinotti, L. R.; Ji, L.; Yuk, M. C.; Desai, A. S.; Cass, N. D.; Amir, Z. A.; Corfas, G.
10.1101/2023.12.14.571732 — neuroscience — Posted on 2024-08-15
2814 DNA methylation correlates with transcriptional noise in response to elevated pCO2 in the eastern oyster (Crassostrea virginica)
Venkataraman, Y. R.; Huffmyer, A. S.; White, S. J.; Downey-Wall, A.; Ashey, J.; Becker, D. M.; Bengtsson, Z.; Putnam, H. M.; Strand, E.; Rodriguez-Casariego, J. A.; Wanamaker, S. A.; Lotterhos, K. E.; Roberts, S.
10.1101/2024.04.04.588108 — physiology — Posted on 2024-08-15
2815 Deep-tissue spatial omics: imaging whole-embryo transcriptomics and subcellular structures at high spatial resolution
Gandin, V.; Kim, J.; Yang, L.-Z.; Lian, Y.; Kawase, T.; Hu, A.; Rokicki, K.; Fleishman, G.; Tillberg, P.; Aguilera Castrejon, A.; Stringer, C.; Preibisch, S.; Liu, Z. J.
10.1101/2024.05.17.594641 — developmental biology — Posted on 2024-08-15
2816 Multiomic analysis reveals developmental dynamics of the human heart in health and disease
Cranley, J.; Kanemaru, K.; Bayraktar, S.; Knight-Schrijver, V.; Pett, J. P.; Polanski, K.; Dabrowska, M.; Mulas, I.; Richardson, L.; Semprich, C.; Kapuge, R.; Perera, S.; He, X.; Ho, S. Y.; Yayon, N.; Tuck, L.; Roberts, K.; Palmer, J.; Davaapil, H.; Gambardella, L.; Patel, M.; Tyser, R.; Sinha, S.; Teichmann, S.
10.1101/2024.04.29.591736 — developmental biology — Posted on 2024-08-15
2817 Disease modification upon brief exposure to tofacitinib during chronic epilepsy.
Hoffman, O. R.; Koehler, J. L.; Espina, J. E. C.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2024-08-15
2819 Multiple Intermediates in the Detergent-Induced Fusion of Lipid Vesicles
Dresser, L. G.; Kunstmann-Olsen, C.; Conteduca, D.; Hofmair, C. M.; Smith, N.; Clark, L.; Johnson, S.; Penedo, C.; Leake, M. C.; Quinn, S. D.
10.1101/2023.09.21.558601 — biophysics — Posted on 2024-08-15
2820 SARS-CoV-2 NSP13 interacts with TEAD to suppress Hippo-YAP signaling
Meng, F.; Kim, J. H.; Tsai, C.-R.; Steimle, J.; Wang, J.; Shi, Y.; Li, R. G.; Xie, B.; Deshmukh, V.; Li, X.; Martin, J.
10.1101/2023.11.30.569413 — cell biology — Posted on 2024-08-15
2822 Conserved role of the SERK-BIR module in development and immunity across land plants
Yan, Y.; Melluh, J.; Mecchia, M. A.; Jeon, H.-W.; Melkonian, K.; Holzberger, C.; Harzen, A.; Stolze, S. C.; Franzen, R.; Hirakawa, Y.; Delgado, A. I. C.; Nakagami, H.
10.1101/2024.08.14.607940 — plant biology — Posted on 2024-08-15
2823 Embracing native diversity to enhance maximum quantum efficiency of photosystem II in maize (Zea mays L.)
Urzinger, S.; Avramova, V.; Frey, M.; Urbany, C.; Scheuermann, D.; Presterl, T.; Reuscher, S.; Ernst, K.; Mayer, M.; Marcon, C.; Hochholdinger, F.; Brajkovic, S.; Ordas, B.; Westhoff, P.; Ouzunova, M.; Schoen, C.-C.
10.1101/2024.08.12.604917 — plant biology — Posted on 2024-08-15
2826 A leaf-expressed TERMINAL FLOWER1 ortholog from coffee with alternate splice forms alters flowering time and inflorescence branching in Arabidopsis
Cardon, C.; Lesy, V.; Fust, C.; Ribeiro, T.; Hebb, O.; de Oliveira, R. R.; Minow, M.; Chalfun-Junior, A.; Colasanti, J.
10.1101/2024.08.14.607758 — plant biology — Posted on 2024-08-15
2829 Increased chloroplast area in the rice bundle sheath through cell specific perturbation of brassinosteroid signalling
Cackett, L.; Luginbuehl, L. H.; Hendron, R.-W.; Plackett, A. R. G.; Stanley, S.; Kelly, S.; Hibberd, J. M.
10.1101/2024.08.14.607565 — plant biology — Posted on 2024-08-15
2830 Evolutionary Origins and Functional Diversification of Auxin Response Factors
Hernandez-Garcia, J.; Carrillo-Carrasco, V. P.; Rienstra, J.; Tanaka, K.; de Roij, M.; Dipp-Alvarez, M.; Freire-Rios, A.; Crespo Garcia, I.; Boer, R.; van den Berg, W.; Lindhoud, S.; Weijers, D.
10.1101/2024.08.14.607941 — plant biology — Posted on 2024-08-15
2832 Performance of phenomic selection in rice: effects of population size and genotype-environment interactions on predictive ability
DE VERDAL, H.; Segura, V.; Pot, D.; Salas, N.; Garin, V.; Rakotoson, T.; Raboin, L.-M.; Vom Brocke, K.; Dusserre, J.; Castro Pacheco, S. A.; Grenier, C.
10.1101/2024.08.15.608050 — plant biology — Posted on 2024-08-15
2837 Larger diet particle sizes cause crickets to grow faster with no effect on final body size
Muzzatti, M. J.; Kong, J. D.; McColville, E. R.; Brzezinski, H.; Stabile, C. C.; MacMillan, H. A.; Bertram, S. M.
10.1101/2024.08.13.607817 — ecology — Posted on 2024-08-15
2839 Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion
Murao, N.; Morikawa, R.; Seino, Y.; Shimomura, K.; Maejima, Y.; Ohno, T.; Yokoi, N.; Yamada, Y.; Suzuki, A.
10.1101/2024.08.15.608033 — cell biology — Posted on 2024-08-15
2841 Age-Related Cerebral Ventriculomegaly occurs in Patients with Primary Ciliary Dyskinesia
Eisenhuth, F. E.; Agbonze, J. E.; Groh, A. M. R.; Rudko, D. A.; Klostranec, J.; Stratton, J. A.; Shapiro, A. J.
10.1101/2024.08.12.607515 — neuroscience — Posted on 2024-08-15
2843 Cortical and behavioural tracking of rhythm in music: Effects of pitch predictability, enjoyment, and expertise
Keitel, A.; Pelofi, C.; Guan, X.; Watson, E.; Wight, L.; Allen, S.; Mencke, I.; Keitel, C.; Rimmele, J. M.
10.1101/2023.10.15.562351 — neuroscience — Posted on 2024-08-15
2844 Muscarinic receptors mediate motivation via preparatory neural activity in humans
Grogan, J. P.; Raemaekers, M.; van Swieten, M. M. H.; Green, A. L.; Gillies, M. J.; Manohar, S. G.
10.1101/2021.07.28.454154 — neuroscience — Posted on 2024-08-15
2845 Field conditions greatly modify a major growth-defense tradeoff in Arabidopsis thaliana
Lundberg, D. S.; Kersten, S.; Mehmetoglu Boz, E.; Pramoj Na Ayutthaya, P.; Zhu, W.; Poersch, K.; Yuan, W.; Swartz, S.; Müller, D.; Bezrukov, I.; Harvest Team, ; Weigel, D.
10.1101/2024.08.15.607984 — plant biology — Posted on 2024-08-15
2846 The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease
Bhalla, S. R.; Wahid, M.; Amartey, J.; Riu, F.; Gao, Y.; Agrawal, J.; Lynch, A. P.; Machado, M. J.; Hawtrey, T.; Kikuchi, R.; Green, K. R.; Teboul, L.; Allen, C.; Blackley, Z.; Rajaji, K.; Marsden, D.; Batson, J.; Harper, S. J.; Oltean, S.; Amoaku, W.; Benest, A. V.; Morris, J. C.; Braithwaite, B.; Bates, D. O.
10.1101/2024.04.17.589996 — physiology — Posted on 2024-08-15
2847 Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway
Plugge, S. F.; Ma, H.; van der Vaart, J. Y.; Sprangers, J.; Morsink, F. H. M.; Xanthakis, D.; Jamieson, C.; Keijzer, A. R.; Margaritis, T.; Candelli, T.; Straver, R.; de Ridder, J.; Holstege, F. C. P.; de Leng, W. W. J.; Offerhaus, G. J. A.; Merenda, A.; Maurice, M. M.
10.1101/2023.07.17.548873 — cancer biology — Posted on 2024-08-15
2848 scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer
Huang, C.; Liu, Z.; Guo, Y.; Wang, W.; Yuan, Z.; Guan, Y.; Pan, D.; Hu, Z.; Sun, L.; Fu, Z.; Bian, S.
10.1101/2024.06.24.600356 — cancer biology — Posted on 2024-08-15
2849 EMhub: a web platform for data management and on-the-fly processing in scientific facilities
De la Rosa Trevin, J. M.; Sharov, G.; Fleischmann, S.; Morado, D.; Bollinger, J. C.; Miller, D. J.; Terry, D. S.; Blanchard, S. C.; Fernandez, I. S.; Carroni, M. S.
10.1101/2024.08.12.607607 — biophysics — Posted on 2024-08-15
2853 Whole Genome Sequencing Analysis of a Recent Multi-Drug Resistant Shigella sonnei Outbreak Among Tunisian Children
Ferjani, S.; Kanzari, L.; Hamzaoui, Z.; Jomni, L.; Ferjani, A.; Fakhfekh, A.; Bahri, O.; Achour, W.; Zribi, M.; Trabelsi, S.; Alya, N. B.; Itani, D.; Bouwazra, S.; Foster-Nyarko, E.; Boubaker, I. B. B.
10.1101/2024.08.12.607540 — genomics — Posted on 2024-08-15
2859 Variable responses of alpine-plant communities to warming and loss of dominant species
Marraffini, M. L.; Classen, A. T.; Sanders, N. J.; Sundquist, M. k.; Deslippe, J. R.; He, J. S.; McLaren, J. R.; Rixen, C.; Wipf, S.; Chisholm, C.; Prager, C.; Stouffer, D. B.
10.1101/2024.08.13.604445 — ecology — Posted on 2024-08-15
2860 Navigating the Landscape of Fear
Gee, M.; Gonzalez-Granda, N.; Joshi, S.; Rudrapatna, N.; Somalwar, A.; Ellner, S.; Vladimirsky, A.
10.1101/2024.08.15.608007 — ecology — Posted on 2024-08-15
2862 Heterogeny in cages: Age-structure and timing of attractant availability impacts fertile egg production in the black soldier fly, Hermetia illucens
Lemke, N. B.; Li, C.; Dickerson, A.; Salazar, D. A.; Rollinson, L. N.; Mendoza, J. E.; Miranda, C. D.; Crawford, S.; Tomberlin, J. K.
10.1101/2024.08.13.607807 — ecology — Posted on 2024-08-15
2864 A test for microbiome-mediated rescue via host phenotypic plasticity in Daphnia
Shahmohamadloo, R. S.; Gabidulin, A. R.; Andrews, E. R.; Fryxell, J. M.; Rudman, S. M.
10.1101/2024.08.14.607994 — ecology — Posted on 2024-08-15
2865 Human footprint and forest disturbance reduce space use of brown bears across Europe.
Hertel, A. G.; Parres, A.; Frank, S. C.; Renaud, J.; Selva, N.; Zedrosser, A.; Balkenhol, N.; Maiorano, L.; Fedorca, A.; Dutta, T.; Bogdanovi_, N.; Bragalanti, N.; Chiriac, S.; Cirovic, D.; Ciucci, P.; Domokos, C.; Fedorca, M.; Filacorda, S.; Findo, S.; Groff, C.; de Gabriel Hernando, M.; Huber, D.; Ionescu, G.; Jerina, K.; Karamanlidis, A. A.; Kindberg, J.; Kojola, I.; Mertzanis, Y.; Palazon, S.; Pop, M. I.; Psaralexi, M.; Quenette, P. Y.; Sergiel, A.; Skuban, M.; Zlatanova, D.; Zwijacz-Kozica, T.; De Barba, M.
10.1101/2024.08.14.607538 — ecology — Posted on 2024-08-15
2866 An ecological, phenotypic and genomic survey of duckweeds with their associated aquatic environments in the United Kingdom
Smith, K. E.; Cowan, L.; Flis, P.; Moore, C.; Heatley, M.; Robles-Zazueta, C. A.; Lee, A.; Yant, L.
10.1101/2024.08.14.607898 — ecology — Posted on 2024-08-15
2870 Synaptic synergy of T cell receptor and interleukin 2 receptor in CD8+ T cells
Capera, J.; Jainarayanan, A. K.; Valvo, S.; Chen, L.; Quayle, S. N.; Moniz, R. J.; Suri, A.; Dustin, M.
10.1101/2024.08.13.607831 — immunology — Posted on 2024-08-15
2871 A versatile correlative light and electron microscopy protocol for human brain and other biological models
Shafiei, N.; Stahli, D.; Burger, D.; Di Fabrizio, M.; Van den Heuvel, L.; Daraspe, J.; Boing, C.; Shahmoradian, S. H.; van de Berg, W. D. J.; Genoud, C.; Stahlberg, H.; Lewis, A.
10.1101/2024.06.11.598271 — neuroscience — Posted on 2024-08-15
2872 Next generation AMA1-based plasmids for enhanced heterologous expression in filamentous fungi
Roux, I.; Woodcraft, C.; Sbaraini, N.; Pepper, A.; Wong, E.; Bracegirdle, J.; Chooi, Y.-H.
10.1101/2024.06.01.596972 — synthetic biology — Posted on 2024-08-15
2874 Live imaging in zebrafish reveals tissue-specific strategies for amoeboid migration
Robertson, T. F.; Schrope, J.; Zwick, Z.; Rindy, J. K.; Horn, A.; Huttenlocher, A.
10.1101/2024.08.14.607647 — cell biology — Posted on 2024-08-15
2876 Introgression across narrow contact zones shapes the genomic landscape of phylogenetic variation in an African bird clade
Rancilhac, L.; de Souza, S. G.; Lukhele, S. M.; Sebastianelli, M.; Ogolowa, B. O.; Moysi, M.; Nikiforou, C.; Asfaw, T.; Downs, C. T.; Brelsford, A.; vonHoldt, B. M.; Kirschel, A. N. G.
10.1101/2024.08.13.607717 — evolutionary biology — Posted on 2024-08-15
2877 Dysregulated Airway Host Defense in Hyper IgE Syndrome due to STAT3 Mutations
Sun, L.; Walls, S. A.; Dang, H.; Quinney, N. L.; Sears, P. R.; Sadritabrizi, T.; Hasegawa, K.; Okuda, K.; Asakura, T.; Chang, X.; Zheng, M.; Mikami, Y.; Dizmond, F. U.; Danilova, D.; Zhou, L.; Deshmukh, A.; Cholon, D. M.; Radicioni, G.; Rogers, T. D.; Kissner, W. J.; Markovetz, M. R.; Guhr Lee, T. N.; Gutay, M. I.; Esther, C. R.; Chua, M.; Grubb, B. R.; Ehre, C.; Kesimer, M.; Hill, D. B.; Ostrowski, L. E.; Button, B.; Gentzsch, M.; Robinson, C.; Olivier, K. N.; Freeman, A. F.; Randell, S. H.; O'Neal, W. K.; Boucher, R. C.; Chen, G.
10.1101/2024.08.14.607930 — cell biology — Posted on 2024-08-15
2879 NOK promotes tumorigenesis through coordinating epidermal growth factor receptor to boost the downstream signaling in breast cancer
Wang, Y.; Zhang, B.; He, C.; Tian, B.; Liu, S.; Li, J.; Wang, J.; Yang, S.; Zhu, B.; Wang, X.; Chang, Z.; Cao, C.
10.1101/2024.08.14.608018 — cell biology — Posted on 2024-08-15
2880 alpha-Actinin-3 deficiency protects from the effects of acute cold exposure through altered skeletal muscle Ca2+ and OXPHOS signaling.
Houweling, P. J.; Tiong, C. F.; Kiriaev, L.; Diaz-Pena, R.; Albers, P. K.; Wood, H.; Wyckelsma, V.; Stait, T.; Venckunas, T.; Valenzuela, P.; Castillo-Garcia, A.; Brazaitis, M.; Berman, Y.; Seto, J. T.; Westerblad, H.; Lek, M.; Thorburn, D.; Lucia, A.; Head, S.; North, K. N.
10.1101/2024.08.14.605938 — cell biology — Posted on 2024-08-15
2885 Phylogenetic proximity drives temporal succession of marine giant viruses in a five-year metagenomic time-series
Laperriere, S. M.; Minch, B.; Weissman, J.; Hou, S.; Yeh, Y.-C.; Ignacio-Espinoza, J. C. L.; Ahlgren, N. A.; Moniruzzaman, M.; Fuhrman, J. A.
10.1101/2024.08.12.607631 — ecology — Posted on 2024-08-15
2886 Microbiota-induced plastic T cells enhance immune control of antigen-sharing tumors
Najar, T. A.; Hao, Y.; Hao, Y.; Romero-Meza, G.; Dolynuk, A.; Littman, D. R.
10.1101/2024.08.12.607605 — immunology — Posted on 2024-08-15
2888 Cognitive dysfunction following brain trauma results from sex-specific reactivation of the developmental pruning processes
Arizanovska, D.; Dallera, C. A.; Folorunso, O. O.; Bush, G. F.; Frye, J. B.; Doyle, K. P.; Jagid, J. R.; Monaco, B. A.; Cordeiro, J. G.; Atkins, C. M.; Griswold, A. J.; Liebl, D. J.
10.1101/2024.08.13.607610 — neuroscience — Posted on 2024-08-15
2889 Cell type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development
Yim, K. M.; Baumgartner, M.; Krenzer, M.; Larios, M. F. R.; Hill-Teran, G.; Nottoli, T.; Muhle, R. A.; Noonan, J. P.
10.1101/2024.08.14.608000 — neuroscience — Posted on 2024-08-15
2894 End-to-end simulation of nanopore sequencing signals with feed-forward transformers
Beslic, D.; Kucklick, M.; Engelmann, S.; Fuchs, S.; Renard, B. Y.; Koerber, N.
10.1101/2024.08.12.607296 — bioinformatics — Posted on 2024-08-15
2898 Cephalopod Sex Determination and its Ancient Evolutionary Origin
Coffing, G. C.; Tittes, S.; Small, S. T.; Songco-Casey, J. O.; Piscopo, D. M.; Pungor, J. R.; Miller, A. C.; Niell, C.; Kern, A. D.
10.1101/2024.02.21.581452 — evolutionary biology — Posted on 2024-08-14
2900 Extracellular ISG15 triggers ISGylation via a type-I interferon independent non-canonical mechanism to regulate host response during virus infection
Miller, L. G.; Chiok, K.; Mariasoosai, C.; Mohanty, I.; Pandit, S.; Deol, P.; Mehari, L.; Teng, M. N.; Haas, A. L.; Natesan, S.; Miura, T. A.; Bose, S.
10.1101/2024.07.05.602290 — immunology — Posted on 2024-08-14
2901 Inhibitory neurons marked by a connectivity molecule regulate memory precision
Tunon-Ortiz, A. B. N.; Trankner, D.; Brockway, S. N.; Raines, O. K.; Mahnke, A.; Grega, M.; Zelikowsky, M.; Williams, M. E.
10.1101/2024.07.05.602304 — neuroscience — Posted on 2024-08-14
2903 Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis
Weiss, T.; Kamalu, M.; Shi, H.; Li, Z.; Amerasekera, J.; Zhong, Z.; Adler, B. A.; Song, M.; Vohra, K.; Wirnowski, G.; Chitkara, S.; Ambrose, C.; Steinmetz, N.; Sridharan, A.; Sahagun, D.; Banfield, J.; Doudna, J.; Jacobsen, S. E.
10.1101/2024.07.17.603964 — plant biology — Posted on 2024-08-14
2904 Enzyme family-centred approach identifies helicases as recurrent hemizygous tumour suppressor genes
Sorensen, C. S.; Weischenfeldt, J.; Favero, F.; Mardin, B.; Li, X.; Olsen, A.; Kashyap, K.; Vossgrone, K.; Rodriguez, G.
10.1101/2024.08.13.607019 — cancer biology — Posted on 2024-08-14
2905 Submolecular-scale Hairpin DNA Folding Dynamics Studied by High-Speed AFM with Optical Tweezers
Umeda, K.; Yamanaka, S.; Imamura, M.; Nagae, F.; Fukuda, S.; Watanabe, H.; Uchihashi, T.; Takada, S.; Ando, T.
10.1101/2024.08.14.605043 — biophysics — Posted on 2024-08-14
2907 Unveiling Mechanistic and Structural Insights of EstS1 Esterase: A Potent Broad-Spectrum Phthalate Diester Degrading Enzyme
VERMA, S.; Choudhary, S.; Kamble, A. K.; Mahto, J. K.; Vamsi K, A. K.; Mishra, I.; Prakash, V. B.; Sircar, D.; Tomar, S.; Sharma, A. K.; Singla, J.; KUMAR, P.
10.1101/2024.08.14.607922 — biophysics — Posted on 2024-08-14
2908 Identification of In Vivo Internalizing Cardiac-Specific RNA Aptamers
Narayan, C.; Lin, L.-H.; Barros, M. B.; Gilbert, T. C.; Brown, C. R.; Reddin, D.; London, B.; Chen, Y.; Wilson, M. E.; Streeter, J.; Thiel, W.
10.1101/2024.08.13.607054 — bioengineering — Posted on 2024-08-14
2909 PURE-seq identifies Egr1 as a Potential Master Regulator in Murine Aging by Sequencing Long-Term Hematopoietic Stem Cells
Pan, S.; Chang, K.-C.; Fernandez-Maestre, I.; Haver, S. V.; Wereski, M. G.; Bowman, R. L.; Levine, R. L.; Abate, A. R.
10.1101/2024.08.12.607664 — bioengineering — Posted on 2024-08-14
2913 The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-alpha-inhibitor regulate crosslinking of the hyaluronan matrix
Shah, A.; Zhang, X.; Snee, M.; Lockhart-Cairns, M. P.; Levy, C. W.; Jowitt, T. A.; Birchenough, H. L.; Dean, L.; Collins, R.; Dodd, R. J.; Roberts, A. R. E.; Enghild, J. J.; Mantovani, A.; Fontana, J.; Baldock, C.; Inforzato, A.; Richter, R. P.; Day, A. J.
10.1101/2024.08.14.607909 — biochemistry — Posted on 2024-08-14
2915 Introgression across narrow contact zones shapes the genomic landscape of phylogenetic variation in an African bird clade
Rancilhac, L.; de Souza, S. G.; Lukhele, S. M.; Sebastianelli, M.; Ogolowa, B. O.; Moysi, M.; Nikiforou, C.; Asfaw, T.; Downs, C. T.; Brelsford, A.; vonHoldt, B. M.; Kirschel, A. N. G.
10.1101/2024.08.13.607717 — evolutionary biology — Posted on 2024-08-14
2918 Genome-wide screen overexpressing mycobacteriophage Amelie genes identifies multiple inhibitors of mycobacterial growth
Tafoya, C.; Ching, B.; Garcia, E. P.; Lee, A.; Acevedo, M.; Bass, K.; Chau, E.; Lin, H.; Mamora, K.; Reeves, M.; Vaca, M.; van Iderstein, W.; Velasco, L.; Williams, V.; Yonemoto, G.; Yonemoto, T.; Heller, D. M.; Diaz, A.
10.1101/2024.08.14.607960 — microbiology — Posted on 2024-08-14
2919 Inferring replication states of bacteria and viruses in enrichment cultures via long-read sequencing
Simon, S. A.; Soares, A.; Bornemann, T. L. V.; Lange, A.; Griesdorn, L.; Fuentes, A.; Dieckmann, M.; Krok, B.; Ruff, S. E.; Hugler, M.; Moraru, C.; Probst, A. J.
10.1101/2024.08.14.607915 — microbiology — Posted on 2024-08-14
2920 Dual CRISPRi-Seq for genome-wide genetic interaction studies identifies key genes involved in the pneumococcal cell cycle
Denereaz, J.; Eray, E.; Jana, B.; de Bakker, V.; Todor, H.; van Opijnen, T.; Liu, X.; Veening, J.-W.
10.1101/2024.08.14.607739 — microbiology — Posted on 2024-08-14
2921 New viruses infecting hyperthermophilic bacterium Thermus thermophilus
Kolesnik, M.; Pavlov, C.; Demkina, A.; Samolygo, A.; Karneyeva, K.; Trofimova, A.; Sokolova, O. S.; Moiseenko, A. V.; Kirsanova, M.; Severinov, K.
10.1101/2024.08.14.607894 — microbiology — Posted on 2024-08-14
2922 Machine learning uncovers gene families impacting oxidative stress resistance across yeasts
Aranguiz, K.; Horianopoulos, L. C.; Elkin, L.; Aba, K. S.; Wrobel, R. L.; Shiu, S.-H.; Rokas, A.; Hittinger, C. T.
10.1101/2024.08.14.607963 — microbiology — Posted on 2024-08-14
2923 Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development
Samper, N.; Haroardottir, L.; Depierreux, D. M.; Song, S. C.; Nakazawa, A.; Gando, I.; Nakamura, T. Y.; Sharkey, A. M.; Nowosad, C. R.; Feske, S.; Colucci, F.; Coetzee, W. A.
10.1101/2024.08.14.608003 — immunology — Posted on 2024-08-14
2924 Protein Carrier AAV
Hoffmann, M. D.; Sorensen, R.; Extross, A.; He, Y.; Schmidt, D.
10.1101/2024.08.14.607995 — synthetic biology — Posted on 2024-08-14
2926 Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains
Rosas-Lemus, M.; Minasov, G.; Brunzelle, J. S.; Taha, T. Y.; Lemak, S.; Yin, S.; Shuvalova, L.; Rosecrans, J.; Khanna, K.; Seifert, H. S.; Savchenko, A.; Stogios, P. J.; Ott, M.; Satchell, K. J.
10.1101/2024.08.13.607777 — microbiology — Posted on 2024-08-14
2927 Surfactin facilitates the establishment of Bacillus subtilis in synthetic communities
Lozano-Andrade, C. N.; Dinesen, C.; Wibowo, M.; Arenos Bach, N.; Hesselberg-Thomsen, V.; Jarmusch, S. A.; Strube, M. L.; Kovacs, A. T.
10.1101/2024.08.14.607878 — microbiology — Posted on 2024-08-14
2928 Distinct bacterial and protist plankton diversity dynamics uncovered through DNA-based monitoring in the Baltic Sea area
Jurdzinski, K. T.; Latz, M. A.; Torstensson, A.; Brugel, S.; Hedblom, M.; Hu, Y. O. O.; Lindh, M.; Andersson, A.; Karlson, B.; Andersson, A. F.
10.1101/2024.08.14.607742 — microbiology — Posted on 2024-08-14
2929 WITHDRAWN: Multiplane Mesoscope reveals distinct cortical interactions following expectation violations
Orlova, N.; Najafi, F.; Tsyboulski, D.; Seid, S.; Kivikas, S.; Kato, I.; Griffin, F.; Leon, A.; L'Heureux, Q.; North, K.; Swapp, J.; Nayan, C.; Hancock, N.; Ahmed, R.; Gelfand, E.; Cho, A.; Mace, K.; Howard, R.; Casal, L.; Lambert, S.; Lee, E. K.; Caldejon, S.; Waughman, X.; Williford, A.; Garrett, M.; Ollerenshaw, D.; Olsen, S. R.; Groblewski, P.; Saggau, P.; Lecoq, J.
10.1101/2020.10.06.328294 — neuroscience — Posted on 2024-08-14
2933 Spatially organized striatal neuromodulator release encodes trajectory errors
Brown, E. H.; Zi, Y.; Vu, M.-A. T.; Bouabid, S.; Lindsey, J.; Godfrey-Nwachukwu, C.; Attarwala, A.; Litwin-Kumar, A.; DePasquale, B.; Howe, M.
10.1101/2024.08.13.607797 — neuroscience — Posted on 2024-08-14
2937 Anatomy of a pest control failure: Introgression of cytochrome P450 337B3 alleles from invasive old-world bollworm into native corn earworm.
Nufer, M. I.; Coates, B. S.; Abel, C. A.; O'Neill, P.; McKracken, M.; Jain, D.; Pierce, C. A.; Glover, J.; Towles, T.; Reddy, G. V. P.; Perera, O. P.
10.1101/2024.03.22.584691 — genetics — Posted on 2024-08-14
2941 Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related multisystem neurodegenerative deficits
Laguna, A.; Penuelas, N.; Gonzalez-Sepulveda, M.; Nicolau, A.; Arthaud, S.; Guilliard-Sirieix, C.; Lorente-Picon, M.; Compte, J.; Miquel-Rio, L.; Xicoy, H.; Liu, J.; Parent, A.; Cuadros, T.; Romero-Gimenez, J.; Pujol, G.; Gimenez-Llort, L.; Fort, P.; Bortolozzi, A.; Carballo-Carbajal, I.; Vila, M.
10.1101/2023.08.08.552400 — neuroscience — Posted on 2024-08-14
2942 Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage
Boerner, K.; Blood, P. D.; Silverstein, J. C.; Ruffalo, M.; Satija, R.; Teichmann, S. A.; Pryhuber, G.; Misra, R. S.; Purkerson, J. M.; Fan, J.; Hickey, J. W.; Molla, G.; Xu, C.; Zhang, Y.; Weber, G. M.; Jain, Y.; Qaurooni, D.; Kong, Y.; HRA Team, ; Bueckle, A.; Herr, B. W.
10.1101/2024.03.27.587041 — bioinformatics — Posted on 2024-08-14
2943 Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain
Zuniga, N.; Earls, N.; Denos, A.; Elison, J.; Jones, B.; Smith, E.; Moran, N.; Brown, K.; Romero, G.; Hyer, C.; Wagstaff, K.; Almughamsi, H.; Transtrum, M.; Price, J. C.
10.1101/2024.08.13.607719 — biochemistry — Posted on 2024-08-14
2946 Engineering anti-amyloid antibodies with transferrin receptor targeting improves brain biodistribution and mitigates ARIA
Pizzo, M. E.; Plowey, E. D.; Khoury, N.; Kwan, W.; Abettan, J.; DeVos, S. L.; Discenza, C. B.; Earr, T.; Joy, D.; Lye-Barthel, M.; Roche, E.; Chan, D.; Dugas, J. C.; Gadkar, K.; Meisner, R.; Sebalusky, J.; Silva Amaral, A. C.; Becerra, I.; Chau, R.; Chow, J.; Clemens, A. J.; Dennis, M. S.; Duque, J.; Fusaro, L.; Getz, J. A.; Kariolis, M. S.; Kim, D. J.; Leung, A. W.-S.; Nguyen, H. N.; Thomsen, E. R.; Sanchez, P. E.; Shan, L.; Silverman, A. P.; Solanoy, H.; Tong, R.; Calvert, M. E. K.; Watts, R. J.; Thorne, R. G.; Weinreb, P. H.; Walsh, D. M.; Lewcock, J. W.; Bussiere, T.; Zuchero, Y. J. Y.
10.1101/2024.07.26.604664 — neuroscience — Posted on 2024-08-14
2947 CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.
Ackloo, S.; Arrowsmith, C. H.; Ban, F.; Barden, C. J.; Beck, H.; Beranek, J.; Berenger, F.; Bolotokova, A.; Bret, G.; Breznik, M.; Carosati, E.; Chau, I.; Chen, Y.; Cherkasov, A.; Della Corte, D.; Denzinger, K.; Dong, A.; Draga, S.; Dunn, I.; Edfeldt, K.; Edwards, A.; Eguida, M.; Eisenhuth, P.; Friedrich, L.; Fuerll, A.; Gardiner, S.; Gentile, F.; Ghiabi, P.; Gibson, E.; Glavatskikh, M.; Gorgulla, C.; Guenther, J.; Gunnarsson, A.; Guseve, F.; Gutkin, E.; Hillisch, A.; Hoffer, L.; Hogner, A.; Irwin, J. J.; Isayev, O.; Ivanova, A.; Jacquemard, C.; Jarrett, A. J.; Jensen, J. H.; Kireev, D.; Klebe
10.1101/2024.07.18.603797 — biochemistry — Posted on 2024-08-14
2948 Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
Van Vranken, J. G.; Li, J.; Mintseris, J.; Wei, T.-Y.; Sniezek, C. M.; Gadzuk-Shea, M.; Gygi, S. P.; Schweppe, D. K.
10.1101/2024.01.26.577428 — biochemistry — Posted on 2024-08-14
2953 A non-catalytic function of a disintegrin and metalloprotease 10 determines hepatic progenitor cell fate
Woehner, B.; Mueller, M.; Pearen, M.; Koehn-Gaone, J.; Gorki, L.; Philippsen, R.; Gogoi-Tiwari, J.; John, C.; Scheja, L.; Krause, F.; Halwachs, B.; Barikbin, R.; Schwinge, D.; Rose-John, S.; Saftig, P.; Schramm, C.; Olynyk, J.; Heeren, J.; Tirnitz-Parker, J. E.; Ramm, G. A.; Schmidt-Arras, D.
10.1101/2024.08.14.607697 — cell biology — Posted on 2024-08-14
2954 Cryo-electron tomography of the actin cytoskeleton and membrane organization during lamellipodia formation using optogenetics
Inaba, H.; Imasaki, T.; Aoyama, K.; Yoshihara, S.; Takazaki, H.; Kato, T.; Goto, H.; Mitsuoka, K.; Nitta, R.; Nakata, T.
10.1101/2024.08.13.607852 — cell biology — Posted on 2024-08-14
2955 Subcellular Region Morphology Reflects Cellular Identity
ROMAN, A. C.; Diaz-Pizarro, A.; Del Valle-Del Pino, N.; Olivera-Gomez, M.; Cumplido-Laso, G.; Benitez, D. A.; Carvajal-Gonzalez, J. M.; Mulero-Navarro, S.
10.1101/2024.08.14.607889 — cell biology — Posted on 2024-08-14
2956 CD24 regulates extracellular vesicle release via an aSMase/PI3K/mTORC2/ROCK/actin pathway in B lymphocytes
Phan, H. D.; Squires, W. R. B.; Mayne, K. E.; Kelly, G. R.; Jafardoust, R.; Christian, S. L.
10.1101/2024.08.14.607772 — cell biology — Posted on 2024-08-14
2957 PDPN/CLEC-2 axis modulates megakaryocyte subtypes in a hematopoietic stem cell-regulating megakaryocyte-dominant manner
Nara, R.; Notoh, H.; Sasaki, T.; Tsukiji, N.; Kamata, A.; Suzuki, N.; Suzuki, A.; Okamoto, S.; Kanematsu, T.; Suzuki, N.; Katsumi, A.; Kojima, T.; Suzuki-Inoue, K.; Matsushita, T.; Tamura, S.
10.1101/2024.08.14.607891 — cell biology — Posted on 2024-08-14
2961 Refined Enterotyping Reveals Dysbiosis in Global Fecal Metagenomes
Keller, M. I.; Nishijima, S.; Podlesny, D.; Kim, C. Y.; Robbani, S. M.; Schudoma, C.; Fullam, A.; Richter, J.; Letunic, I.; Akanni, W.; Orakov, A.; Schmidt, T. S.; Marotta, F.; Trebicka, J.; Kuhn, M.; Van Rossum, T.; Bork, P.
10.1101/2024.08.13.607711 — microbiology — Posted on 2024-08-14
2963 Decoding the Microbiome-Metabolome Nexus: A Systematic Benchmark of Integrative Strategies
Mangnier, L.; Bodein, A.; Mariaz, M.; Scott-Boyer, M.-P.; Mathieu, A.; Vashist, N.; Bramble, M.; Droit, A.
10.1101/2024.01.26.577441 — bioinformatics — Posted on 2024-08-14
2965 H2A.Z deposition at meiotic prophase I underlies homologous recombination and pachytene genome activation during male meiosis
Sun, S.; Jiang, Y.; Jiang, N.; Zhang, Q.; Pan, H.; Huang, F.; Zhang, X.; Guo, Y.; You, X.; Gong, K.; Wei, W.; Liu, H.; Song, Z.; Song, Y.; Tang, X.; Yu, M.; Li, R.; Lin, X.
10.1101/2024.06.06.597721 — developmental biology — Posted on 2024-08-14
2968 CRISPR-Cas9 mediated deletions of FvMYB46 reduces fruit set and biosynthesis of flavonoids in Fragaria vesca
Rai, A.; Skarn, M. N.; Tengs, T.; Elameen, A.; Amundsen, M. R.; Bjora, O. S.; Haugland, L. K.; Yakovlev, I. A.; Brurberg, M. B.; Thorstensen, T.
10.1101/2024.08.07.607017 — plant biology — Posted on 2024-08-14
2970 Change in functional trait diversity mediates the effects of nutrient addition on grassland stability
Chen, Q.; Wang, S.-P.; Seabloom, E. W.; Isbell, F.; Borer, E. T.; Bakker, J. D.; Bharath, S.; Roscher, C.; Peri, P. L.; Power, S. A.; Donohue, I.; Stevens, C.; Ebeling, A.; Nogueira, C.; Caldeira, M. C.; MacDougall, A.; Moore, J.; Bagchi, S.; Jentsch, A.; Tedder, M.; Kirkman, K.; Alberti, J.; Hautier, Y.
10.1101/2022.09.16.508233 — ecology — Posted on 2024-08-14
2972 Recombinant dimeric PDZ protein inhibitors for long-term relief of chronic pain by AAV therapeutics
Noes-Holt, G.; Jensen, K. L.; Richner, M.; Baro, R. C.; Sivertsen, L.; Jager, S. E.; Fernandez, L. J.; Andersen, R. C.; Lilja, J. H.; Larsen, A. H.; Kowenicki, M. B.; Boesgaard, S. P.; Houser, G. A.; Christiansen, N. R.; Tappe-Theodor, A. E.; Vaegter, C. B.; Kuner, R.; Madsen, K. L.; Soerensen, A. T.
10.1101/2023.03.03.530962 — neuroscience — Posted on 2024-08-14
2974 A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D
Villegas-Valencia, M.; Stark, M. R.; Seger, M.; Wellman, G. B.; Overmans, S.; Lammers, P. J.; Rader, S. D.; Lauersen, K. J.
10.1101/2024.07.30.605877 — bioengineering — Posted on 2024-08-14
2975 Low T cell diversity is associated with poor outcome in bladder cancer: a comprehensive longitudinal analysis of the T cell receptor repertoire
Kjaer, A.; Kristjansdottir, N.; Juul, R. I.; Nordentoft, I.; Birkenkamp-Demtroder, K.; Ahrenfeldt, J.; Strandgaard, T.; Radif, D.; Hodgson, D.; Abbosh, C.; Aerts, H. J.; Agerbaek, M.; Jensen, J. B.; Birkbak, N. J.; Dyrskjot, L.
10.1101/2024.05.30.596555 — cancer biology — Posted on 2024-08-14
2979 MIRO1 controls energy production and proliferation of smooth muscle cells
Qian, L.; Koval, O. M.; Endoni, B. T.; Juhr, D.; Stein, C. C.; Allamargot, C.; Lin, L.-H.; Guo, D.-F.; Rahmouni, K.; Boudreau, R. L.; Streeter, J.; Thiel, W. H.; Grumbach, I. M.
10.1101/2024.08.13.607854 — cell biology — Posted on 2024-08-13
2981 A multi-model approach defines function altering MECP2 missense variants identified in individuals with autism spectrum disorder
Loewen, C.; Chen, E.; Schmitt, J.; McIntosh, G.; Singh, A.; Young, B.; Lian, T.; Liu, J.; Khan, V.; Chen, K.; Liston, J. B.; MacDonald, L.; Wang, B.; Medina Giro, S.; Boehme, B.; Das, M.; Indran, S.; Rogic, S.; Pavlidis, P.; Chao, J.; Allan, D. W.
10.1101/2024.08.13.607763 — neuroscience — Posted on 2024-08-13
2983 A bone-derived protein primes rapid visual escape via GPR37 receptor in a subpopulation of VTA GABAergic neurons
Liu, X.; Lai, J.; Gao, X.; Wang, L.; Hu, Y.; Liao, G.; Ma, S.; Feng, B.; Yang, L.; Qian, Z.; Tan, L.; Li, X.; Wang, L.
10.1101/2024.08.12.607510 — neuroscience — Posted on 2024-08-13
2984 Lower Aperiodic Activity is Associated with Reduced Verbal Fluency Performance Across Adulthood
McKeown, D. J.; Roberts, E.; Finley, A. J.; Kelley, N. J.; Keage, H. A. D.; Schinazi, V. R.; Baumann, O.; Moustafa, A. A.; Angus, D. J.
10.1101/2024.08.13.607827 — neuroscience — Posted on 2024-08-13
2985 Population coding of predator imminence in the hypothalamus
Cheung, K. Y. M.; Nair, A.; Li, L.-y.; Shapiro, M. G.; Anderson, D. J.
10.1101/2024.08.12.607651 — neuroscience — Posted on 2024-08-13
2986 Human-specific features of cerebellar astrocytes and Purkinje cells: an anatomical comparison with mice and macaques
Hercher, C.; Ellerbeck, K.; Toutee, L.; Ye, X.; Mpai, R.; Davoli, M. A.; Watt, A. J.; Murai, K. K.; Turecki, G.; Mechawar, N.
10.1101/2024.08.13.607849 — neuroscience — Posted on 2024-08-13
2987 Cognitive dysfunction following brain trauma results from sex-specific reactivation of the developmental pruning processes
Arizanovska, D.; Dallera, C. A.; Folorunso, O. O.; Bush, G. F.; Frye, J. B.; Doyle, K. P.; Jagid, J. R.; Monaco, B. A.; Cordeiro, J. G.; Atkins, C. M.; Griswold, A. J.; Liebl, D. J.
10.1101/2024.08.13.607610 — neuroscience — Posted on 2024-08-13
2989 Axonal mitochondria regulate gentle touch response through control of axonal actin dynamics
Hegde, S.; Modi, S.; Deih, E. W.; Glomb, O. V.; Yogev, S.; Hoerndli, F.; Koushika, S. P.
10.1101/2024.08.13.607780 — cell biology — Posted on 2024-08-13
2990 Galvanotactic directionality of cell groups depends on group size
Copos, C.; sun, y.; Zhu, K.; Zhang, Y.; Reid, B.; Draper, B. W.; Lin, F.; Yue, H.; Bernadskaya, Y.; Zhao, M.; Mogilner, A.
10.1101/2024.08.13.607794 — cell biology — Posted on 2024-08-13
2991 One step 4x and 12x 3D-ExM: robust super-resolution microscopy in cell biology
Norman, R.; Chen, Y.-C.; Recchia, E.; Loi, J.; Rosemarie, Q.; Lesko, S.; Patel, S.; Sherer, N. M.; Takaku, M.; Burkard, M.; Suzuki, A.
10.1101/2024.08.13.607782 — cell biology — Posted on 2024-08-13
2992 Mannose receptor (MRC1) mediates uptake of dextran in macrophages via receptor-mediated endocytosis
Wollman, J.; Wanniarachchi, K.; Pradhan, B.; Huang, L.; Kerkvliet, J. G.; Hoppe, A. D.; Thiex, N. W.
10.1101/2024.08.13.607841 — cell biology — Posted on 2024-08-13
2996 Single-cell transcriptomics reveals cellular hierarchies and aberrant CTS contraction-mediated premature hair regression in androgenetic alopecia
Li, G.; Yang, L.; Duan, S.; Chen, M.; Zhang, Y.; Liu, F.; Tang, Y.; Wang, Y.; Li, J.; Xu, S.; Wu, Z.; Wang, B.; Zhao, Z.; Shi, W.; Xie, H.; Deng, Z.; Li, J.
10.1101/2023.12.25.573294 — pathology — Posted on 2024-08-13
2997 The Aryl Hydrocarbon Receptor Controls IFNγ-Induced Immune Checkpoints PD-L1 and IDO via the JAK/STAT Pathway in Lung Adenocarcinoma
Snyder, M.; Wang, Z.; Lara, B.; Fimbres, J.; Pichardo, T.; Mazzilli, S. A.; Kahn, M. M.; Duggineni, V.; Monti, S.; Sherr, D. H.
10.1101/2024.08.12.607602 — cancer biology — Posted on 2024-08-13
2999 A simple method for methanol quantification in Spirits using UV Visible Spectroscopy and FTIR
Shadrack, R. S.; Kotra, K. K.; Tari, D.; Tabi, H.; Botleng, J.; Kelep, R.; Regenvanu, L.
10.1101/2024.08.12.607685 — biochemistry — Posted on 2024-08-13
3003 Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis
Nishi, K.; Sakamaki, T.; Nagasaka, A.; Kao, K. S.; Sadaoka, K.; Asano, M.; Yamamoto, N.; Takaori-Kondo, A.; Miyanishi, M.
10.1101/2024.01.18.576239 — developmental biology — Posted on 2024-08-13
3005 Compound screening in primary human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies
Ishii, Y.; Orr, J. C.; El Mdawar, M.-B.; Bairros de Pilger, D. R.; Pearce, D. R.; Lazarus, K. A.; Graham, R. E.; Nikolic, M. Z.; Ketteler, R.; Carragher, N. O.; Janes, S. M.; Hynds, R. E.
10.1101/2024.08.13.606573 — cell biology — Posted on 2024-08-13
3006 Single-Molecule Barcoding Technology for Single-Cell Genomics
Garcia-Bassets, I.; Mo, G.; Xia, Y.; Wu, T.-C.; Mekuria, I.; Mikhaylova, V.; Rzepka, M.; Kawamura, T.; Chang, P. L.; Paasch, A.; Pham, L.; Venugopal, S. S.; Sanchez, S.; de Souza, J. S.; Yao, L.; Gu, S.; Bodai, Z.; Komor, A. C.; Muotri, A. R.; Wang, J.; Wang, Y.; Lei, M.; Almenar-Queralt, A.; Chen, Z.
10.1101/2024.08.13.607508 — molecular biology — Posted on 2024-08-13
3007 Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions
Chen, T.-W.; Liao, H.-W.; Noble, M.; Siao, J.-Y.; Cheng, Y.-H.; Chiang, W.-C.; Lo, Y.-T.; Chang, C.-T.
10.1101/2023.09.04.556219 — molecular biology — Posted on 2024-08-13
3008 Control of pili synthesis and putrescine homeostasis in Escherichia coli
Mehta, I.; Hogins, J.; Hall, S.; Vragel, G.; Ambagaspitiye, S.; Zimmern, P. E.; Reitzer, L.
10.1101/2024.08.13.607059 — microbiology — Posted on 2024-08-13
3009 SICKO: Systematic Imaging of Caenorhabditis Killing Organisms
Espejo, L. S.; Freitas, S.; Hofschneider, V.; Chang, L.; Antenor, A.; Balsa, J.; Haskins, A.; DeNicola, D.; Dang, H.; Hamming, S.; Kelser, D.; Sutphin, G. L.
10.1101/2023.02.17.529009 — immunology — Posted on 2024-08-13
3010 Brain Age Prediction: Deep Models Need a Hand to Generalize
Rajabli, R.; Soltaninejad, M.; Fonov, V.; Bzdok, D.; Collins, L.
10.1101/2024.06.11.598576 — neuroscience — Posted on 2024-08-13
3012 Cross-species real time detection of trends in pupil size fluctuation
Kronemer, S. I.; Gobo, V. E.; Walsh, C. R.; Teves, J. B.; Burk, D. C.; Shahsavarani, S.; Gonzalez-Castillo, J.; Bandettini, P. A.
10.1101/2024.02.12.579393 — neuroscience — Posted on 2024-08-13
3013 Untargeted metabolomics reveals anion and organ-specific biochemistry of salinity tolerance in willow
Sas, E.; Fremont, A.; Gonzalez, E.; Sarrazin, M.; Barnabe, S.; Labrecque, M.; Brereton, n. J. B.; Pitre, F. E.
10.1101/2024.07.16.603755 — plant biology — Posted on 2024-08-13
3014 An extra-glycolytic function for hexokinase 2 as an RNA-binding protein regulating SOX10 mRNA translation in melanoma
Dian, A.-L.; Moya-Plana, A.; Claps, G.; Labbe, C. M.; Quidville, V.; Baille, D.; Roy, S.; Raynal, V.; Baulande, S.; Robert, C.; Vagner, S.
10.1101/2024.08.13.607712 — cancer biology — Posted on 2024-08-13
3015 The pro-tumoral and anti-tumoral roles of EphA4 on T regulatory cells and tumor associated macrophages during HNSCC tumor progression.
Corbo, S.; Nguyen, D.; Bhatia, S.; Darragh, L. B.; Abdelazeem, K. N. M.; Van Court, B.; Olimpo, N. A.; Gadwa, J.; Yu, J.; Hodgson, C.; Samedi, V.; Garcia, E. S.; Siu, L.; Saviola, A.; Heasley, L. E.; Knitz, M. W.; Pasquale, E. B.; Karam, S. D.
10.1101/2024.08.13.607778 — cancer biology — Posted on 2024-08-13
3017 A Chemoenzymatic Strategy for Site-Specific Glyco-Tagging of Native Proteins for the Development of Biologicals
Gimeno, A.; Ehlers, A. M.; Delgado, S.; Langenbach, J.-W. H.; van den Bos, L. J.; Kruijtzer, J. A. W.; Guigas, B. G. A.; Boons, G.-J.
10.1101/2024.08.13.607754 — biochemistry — Posted on 2024-08-13
3019 An Automated High-throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition
Jing, H.; Richardson, P. L.; Potts, G. K.; Senaweera, S.; Marin, V. L.; McClure, R. A.; Banlasan, A.; Tang, H.; Kath, J.; Ma, R.; Williams, J.
10.1101/2024.08.13.607785 — biochemistry — Posted on 2024-08-13
3021 Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain
Zuniga, N.; Earls, N.; Denos, A.; Elison, J.; Jones, B.; Smith, E.; Moran, N.; Brown, K.; Romero, G.; Hyer, C.; Wagstaff, K.; Almughamsi, H.; Transtrum, M.; Price, J. C.
10.1101/2024.08.13.607719 — biochemistry — Posted on 2024-08-13
3023 Sequence-directed covalent protein-RNA linkages using engineered HUH-Tags
Smiley, A.; Babilonia-Diaz, N.; Krueger, A. J.; Aihara, H.; Tompkins, K. J.; Lemmex, A. C.; Gordon, W. R.
10.1101/2024.08.13.607811 — biochemistry — Posted on 2024-08-13
3024 A Light Sensitive Hyaluronic Acid-based Hydrogel for 3D Culturing, Differentiation, and Harvesting of Mesenchymal Stromal Cells
Palmieri, F.; Gueye, M.; Vicario del Rio, L.; Bunschuh, S.; Chopra, P.; Mihaila, S.; Vermonden, T.; Levato, R.; Boons, G.-J.
10.1101/2024.08.13.607705 — biochemistry — Posted on 2024-08-13
3029 Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of Enterococcus faecalis
Zlitni, S.; Bowden, S.; Sberro, H.; Torres, M. D. T.; Vaughan, J. M.; Pinto, A. F. M.; Pinto, Y.; Fernandez, D.; Rost, H.; Saghatelian, A.; de la Fuente-Nunez, C.; Bhatt, A. S.
10.1101/2024.08.13.607696 — microbiology — Posted on 2024-08-13
3030 Refined Enterotyping Reveals Dysbiosis in Global Fecal Metagenomes
Keller, M. I.; Nishijima, S.; Podlesny, D.; Kim, C. Y.; Robbani, S. M.; Schudoma, C.; Fullam, A.; Richter, J.; Letunic, I.; Akanni, W.; Orakov, A.; Schmidt, T. S.; Marotta, F.; Trebicka, J.; Kuhn, M.; Van Rossum, T.; Bork, P.
10.1101/2024.08.13.607711 — microbiology — Posted on 2024-08-13
3031 Porcine Nasal Organoids as a model to study the interactions between the swine nasal microbiota and the host
Bonillo-Lopez, L.; Carmona-Vicente, N.; Tarres-Freixas, F.; Kochanowski, K.; Martinez, J.; Perez, M.; Sibila, M.; Correa-Fiz, F.; Aragon, V.
10.1101/2024.08.13.606910 — microbiology — Posted on 2024-08-13
3033 FhaA plays a key role in mycobacterial polar elongation and 1 asymmetric growth
Rosello, J.; Rivera, B.; Fialho, M. A.; Augusto, I.; Gil, M.; Forrellad, M. A.; Bigi, F.; Tano, A. R.; Urdaniz, E.; Piuri, M.; Miranda, K.; Wehenkel, A. M.; Alzari, P. M.; Malacrida, L.; Duran, R.
10.1101/2024.08.13.607006 — microbiology — Posted on 2024-08-13
3036 Interpretable representation learning for 3D multi-piece intracellular structures using point clouds
Vasan, R.; Ferrante, A. J.; Borensztejn, A.; Frick, C. L.; Gaudreault, N.; Mogre, S. S.; Morris, B.; Pires, G. G.; Rafelski, S. M.; Theriot, J. A.; Viana, M. P.
10.1101/2024.07.25.605164 — cell biology — Posted on 2024-08-13
3037 Mfn2 induces NCLX-mediated calcium release from mitochondria.
Kolitsida, P.; Saha, A.; Caliri, A. W.; Assali, E.; Riera, A. M.; Itskanov, S.; Magana, C. S.; Stork, B.; Shirihai, O. S.; Sekler, I.; Koehler, C. M.; van der Bliek, A. M.
10.1101/2024.08.05.606704 — cell biology — Posted on 2024-08-13
3038 Motor training improves impaired cortico-cerebellar connectivity in cerebellar ataxia
Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.
10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-08-13
3039 Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma
Jonsson, G.; Hofmann, M.; Oliveira, T.; Lemberger, U.; Stejskal, K.; Krssakova, G.; Sakic, I.; Novatchkova, M.; Mereiter, S.; Grabmann, G.; Koecher, T.; Kikic, Z.; Rechberger, G. N.; Zuellig, T.; Englinger, B.; Schmidinger, M.; Penninger, J. M.
10.1101/2024.08.12.607453 — cancer biology — Posted on 2024-08-13
3040 Building, Benchmarking, and Exploring Perturbative Maps of Transcriptional and Morphological Data
Celik, S.; Huetter, J.-C.; Melo-Carlos, S.; Lazar, N.; Mohan, R.; Tillinghast, C.; Biancalani, T.; Fay, M.; Earnshaw, B.; Haque, I.
10.1101/2022.12.09.519400 — bioinformatics — Posted on 2024-08-13
3041 Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations
Kobren, S. N.; Moldovan, M. A.; Reimers, R.; Traviglia, D.; Li, X.; Barnum, D.; Veit, A.; Corona, R. I.; Carvalho, G. d. V.; Willett, J.; Berselli, M.; Ronchetti, W.; Nelson, S. F.; Martinez-Agosto, J. A.; Sherwood, R.; Krier, J.; Kohane, I. S.; Undiagnosed Diseases Network, ; Sunyaev, S. R.
10.1101/2024.02.13.580158 — genetics — Posted on 2024-08-13
3046 Sleep defined by arousal threshold reveals decreases in corticocortical functional correlations independently from the conventional sleep stages
Picchioni, D.; Yang, F. N.; de Zwart, J. A.; Wang, Y.; Mandelkow, H.; Ozbay, P. S.; Chen, G.; Taylor, P. A.; Lam, N.; Chappel-Farley, M. G.; Chang, C.; Liu, J.; van Gelderen, P.; Duyn, J. H.
10.1101/2024.08.09.607376 — neuroscience — Posted on 2024-08-13
3047 Upregulation of DEK Expression in Uterine Myomas and Cervical Cancer as a Potential Prognostic Factor
Janiak, A.; Liu, X.; Koviazina, R.; Tan, P.; Kappes, F.; Sheng, F.; Petraglia, F.; Donati, C.; Tsigkou, A.
10.1101/2024.08.12.607532 — cancer biology — Posted on 2024-08-13
3048 SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis
Li, X.; Pechuan Jorge, X.; Risom, T.; Foo, C.; Prilipko, A.; Zubkov, A.; Chan, C.; Chang, P.; Peale, F.; Ziai, J.; Rost, S.; Hibar, D.; McGinnis, L.; Tabatsky, E.; Ye, X.; Bravo, H. C.; Shi, Z.; Nowicka, M.; Scherdin, J.; Cowan, J.; Giltnane, J.; Orlova, D.; Jesudason, R.
10.1101/2022.08.22.504841 — bioinformatics — Posted on 2024-08-13
3052 Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation
Zeeshan, M.; Rashpa, R.; Ferguson, D. J.; Mckeown, G.; Nugmanova, R.; Subodhi, A. K.; Beyeler, R.; Pashley, S. L.; Markus, R.; Brady, D.; Roques, M.; Bottrill, A. R.; Fry, A. M.; Pain, A.; vaughan, s.; Holder, A. A.; Tromer, E. C.; Brochet, M.; Tewari, R.
10.1101/2024.02.05.578160 — cell biology — Posted on 2024-08-13
3054 Sensory neurons regulate stimulus-dependent humoral immunity
Aguilar, D.; Zhu, F.; Millet, A.; Millet, N.; Germano, P.; Pisegna, J.; Akbari, O.; Doherty, T. A.; Swidergall, M.; Jendzjowsky, N.
10.1101/2024.01.04.574231 — immunology — Posted on 2024-08-13
3058 Pharmacological GCase Activity Enhancement Inhibits Tau Accumulation
Ciccaldo, M.; Perez-Carmona, N.; Piovesana, E.; Cano-Crespo, S.; Ruano, A.; Delgado, A.; Fregno, I.; Calvo-Flores Guzman, B.; Bellotto, M.; Molinari, M.; Taylor, J.; Papin, S.; Garcia-Collazo, A. M.; Paganetti, P.
10.1101/2024.08.13.607706 — cell biology — Posted on 2024-08-13
3059 Real-time identification of carbapenemase-producing Klebsiella pneumoniae lineages and outbreak detection using FT-IR ATR
Goncalves, A. B.; Alves, V.; Neves, I.; Read, A.; Pinheiro, N.; Henius, A. E.; Hasman, H.; Peixe, L.; Novais, A.
10.1101/2024.08.12.607659 — microbiology — Posted on 2024-08-13
3060 Deciphering Cargo Contents in Extracellular Vesicles of Candida haemulonii var. vulnera
de Oliveira, B. T. M.; Bitencourt, T. A.; Santos, P.; Pagano, A. D.; Pessoni, A. M.; Rezende, C. P.; Piraine, R. E. A.; Masson, A. P.; Faca, V. M.; Campos, V. F.; Alves, L. R.; Lopes Colombo, A.; Almeida, F.
10.1101/2024.08.12.607614 — microbiology — Posted on 2024-08-13
3066 Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping
Kyratzi, P.; Matika, O.; Brassington, A. H.; Connie, C. E.; Xu, J.; Barrett, D. A.; Emes, R. D.; Archibald, A. L.; Paldi, A.; Sinclair, K. D.; Wattis, J.; Rauch, C.
10.1101/2024.04.16.589524 — genetics — Posted on 2024-08-13
3067 Optogenetic tools for inducing organelle membrane rupture
Nagashima, Y.; Eguchi, T.; Koyama-Honda, I.; Mizushima, N.
10.1101/2024.08.13.607738 — cell biology — Posted on 2024-08-13
3071 Selecting sites for strategic surveillance of zoonotic pathogens: a case study in Panama
Cobos, M. E.; Dunnum, J. L.; Armien, B.; Gonzalez, P.; Juarez, E.; Salazar, J. R.; Cook, J. A.; Colella, J. P.
10.1101/2024.08.12.607103 — ecology — Posted on 2024-08-13
3073 Arp2/3 iso-complexes limit t-tubule overgrowth to ensure myofiber formation and synchronous contraction
Pereira, A. R.; Soares, A. d. R.; Liu, T.; Ferreira, J. L.; Leal, G.; Faleiro, I.; Kogata, N.; Way, M.; Moores, C.; Gomes, E. R.
10.1101/2024.08.13.607563 — cell biology — Posted on 2024-08-13
3079 Non-Human Recognition of Orthography: How is it implemented and how does it differ from Human orthographic processing
Gagl, B.; Weyers, I.; Eisenhauer, S.; Fiebach, C. J.; Colombo, M.; Scarf, D.; Ziegler, J. C.; Grainger, J.; Guentuerkuen, O.; Mueller, J. L.
10.1101/2024.06.25.600635 — animal behavior and cognition — Posted on 2024-08-13
3082 PINDER: The protein interaction dataset and evaluation resource
Kovtun, D.; Akdel, M.; Goncearenco, A.; Zhou, G.; Holt, G.; Baugher, D.; Lin, D.; Adeshina, Y.; Castiglione, T.; Wang, X.; Marquet, C.; McPartlon, M.; Geffner, T.; Rossi, E.; Corso, G.; Stark, H.; Carpenter, Z.; Kucukbenli, E.; Bronstein, M.; Naef, L.
10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-08-13
3087 Spontaneous calcium transients in hair cell stereocilia
Hussain, S.; Sedlacek, M.; Cui, R.; Zhang-Hooks, W.; Bergles, D. E.; Shin, J.-B.; Kindt, K.; Kachar, B.
10.1101/2024.08.12.607658 — cell biology — Posted on 2024-08-13
3089 The regulation of polar flagella assembly in Pseudomonas putida
Pulido-Sanchez, M.; Leal-Morales, A.; Lopez-Sanchez, A.; Cava, F.; Govantes, F.
10.1101/2023.12.15.571843 — microbiology — Posted on 2024-08-13
3090 Tertiary lymphoid structures are associated with enhanced macrophage activation, immune checkpoint expression and predict outcome in cervical cancer.
Gorvel, L.; Panouillot, M.; Rouviere, M.-S.; Billon, E.; Fattori, S.; Sonongbua, J.; Boucherit, N.; Ben Amara, A.; Quilichini, O.; GRANJEAUD, S.; Degos, C.; Carcopino, X.; Lambaudie, E.; Chretien, A.-S.; Sabatier, R.; Dieu-Nosjean, M.-C.; Olive, D.
10.1101/2023.08.17.552583 — immunology — Posted on 2024-08-13
3091 A transposase-derived gene required for human brain development
Jubierre Zapater, L.; Lewis, S.; Lopez Gutierrez, R.; Yamada, M.; Rodriguez Fos, E.; Planas-Felix, M.; Cameron, D.; Demarest, P.; Nabila, A.; Mueller, H.; Zhao, J.; Bergin, P.; Reed, C.; Chwat-Edelstein, T.; Pagnozzi, A.; Nava, C.; Bourel-Ponchel, E.; Dursun, A.; Ozgul, R. K.; Tuna Akar, H.; Maroofian, R.; Houlden, H.; Arshad Cheema, H.; Nadeem Anjum, M.; Zifarelli, G.; Essid, M.; Ben Hafsa, M.; Benrhouma, H.; Proekt, A.; Zhao, X.; Socci, N.; Hayes, M.; Bigot, Y.; Rabadan, R.; Torrents, D.; Kleinman, C. L.; Kruer, M. C.; Toth, M.; Kentsis, A.
10.1101/2023.04.28.538770 — neuroscience — Posted on 2024-08-13
3092 Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling
Le Gac, B.; Tournissac, M.; Belzic, E.; Picaud, S.; Dusart, I.; Soula, H.; Li, D.; Charpak, S.; Cauli, B.
10.1101/2024.03.27.586974 — neuroscience — Posted on 2024-08-13
3093 Influence of feedback transparency on motor imagery neurofeedback performance: the contribution of agency
Dussard, C.; Pillette, L.; Dumas, C.; Pierrieau, E.; Hugueville, L.; Lau, B.; Jeunet, C.; George, N.
10.1101/2024.02.27.582270 — neuroscience — Posted on 2024-08-13
3095 Modelling inflammation-induced peripheral sensitization in a dish - more complex than expected?
Li, Y.; Lock, A.; Fedele, L.; Zebochin, I.; Sabate, A.; Siddle, M.; Cainarca, S.; Röderer, P.; Montag, K.; Tarroni, P.; Brüstle, O.; Shaw, T.; Taams, L.; Denk, F.
10.1101/2024.08.12.607558 — neuroscience — Posted on 2024-08-13
3098 Modeling Immunoglobulin light chain amyloidosis in Caenorhabditis elegans
Romeo, M.; Barzago, M. M.; Corbelli, A.; Maglioni, S.; Ventura, N.; Natale, C.; Conz, A.; Salmona, M.; Palladini, G.; Nuvolone, M.; Fiordaliso, F.; Merlini, G.; Diomede, L.
10.1101/2024.07.05.602215 — pathology — Posted on 2024-08-13
3099 Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation
Matsuo-Takasaki, M.; Kambayashi, S.; Hemmi, Y.; Wakabayashi, T.; Shimizu, T.; An, Y.; Ito, H.; Takauchi, K.; Ibuki, M.; Kawashima, T.; Masayasu, R.; Suzuki, M.; Nishishita, N.; Kawai, Y.; Umekage, M.; Kato, T. M.; Noguchi, M.; Nakade, K.; Nakamura, Y.; Nakaishi, T.; Tsukahara, M.; Hayashi, Y.
10.1101/2023.10.08.561419 — bioengineering — Posted on 2024-08-13
3101 DNA polymerase Lambda is anchored within the NHEJ synaptic complex via Ku70/80
Frit, P.; Amin, H.; Zahid, S.; Barboule, N.; Hall, C.; Matharu, G.; Hardwick, S. W.; Chauvat, J.; Britton, S.; Chirgadze, D. Y.; Ropars, V.; Charbonnier, J.-B.; Calsou, P.; Chaplin, A. K.
10.1101/2024.08.12.607588 — biochemistry — Posted on 2024-08-13
3102 Phylogenomic Insights into the Evolution and Origin of Nematoda
Qing, X.; Zhang, Y. M.; Sun, S.; Ahmed, M.; Lo, W.-S.; Bert, W.; Holovachov, O.; Li, H.
10.1101/2023.12.13.571554 — genomics — Posted on 2024-08-13
3108 Phosphate-dependent nuclear export via a novel NES class recognized by exportin Msn5
Fung, H. Y. J.; Mittal, S. R.; Niesman, A. B.; Jiou, J.; Shakya, B.; Yoshizawa, T.; Cansizoglu, A. E.; Rout, M. P.; Chook, Y. M.
10.1101/2024.08.12.607649 — biophysics — Posted on 2024-08-12
3109 Cross-species imputation and comparison of single-cell transcriptomic profiles
Zhang, R.; Yang, M.; Schreiber, J.; ODay, D. R.; Turner, J.; Shendure, J.; Disteche, C. M.; Deng, X.; Noble, W. S.
10.1101/2023.10.19.563173 — bioinformatics — Posted on 2024-08-12
3111 Altering translation allows E. coli to overcome chemically stabilized G-quadruplexes
Cueny, R. R.; Voter, A. F.; McKenzie, A. M.; Morgenstern, M.; Myers, K. S.; Place, M. M.; Peters, J. M.; Coon, J. J.; Keck, J. L.
10.1101/2024.08.12.607615 — biochemistry — Posted on 2024-08-12
3112 A Novel Blood-Based Epigenetic Clock for Intrinsic Capacity Predicts Mortality and is Associated with Clinical, Immunological and Lifestyle Factors
Fuentealba, M.; Rouch, L.; Guyonnet, S.; Lemaitre, J.-M.; de Souto Barreto, P.; Vellas, B.; Andrieu, S.; Furman, D.
10.1101/2024.08.09.607252 — genomics — Posted on 2024-08-12
3115 Bovine highly pathogenic avian influenza virus stability and inactivation in the milk byproduct lactose
Kwon, T.; Gebhardt, J.; Lyoo, E.; Nooruzzaman, M.; Gaudreault, N. N.; Morozov, I.; Diel, D.; Richt, J. A.
10.1101/2024.08.12.607665 — microbiology — Posted on 2024-08-12
3117 Development of a highly efficient base editing system for Lactobacilli to improve probiotics and dissect essential functions
Mitsunobu, H.; Kita, Y.; Nambu-Nishida, Y.; Miyazaki, S.; Nakajima, K.; Taoka, K.-i.; Kondo, A.; Nishida, K.
10.1101/2024.08.12.607654 — microbiology — Posted on 2024-08-12
3118 Characteristics of human donor lungs utilized for research
Sarkar, N. R.; Garnica, L. A.; Stahlschmidt, E.; Byers, D. E.; Kulkarni, H. S.
10.1101/2024.08.10.607431 — immunology — Posted on 2024-08-12
3119 A novel candidate neuromarker of central motor dysfunction in childhood apraxia of speech
Anastasopoulou, I.; Cheyne, D. O.; Lieshout, P. V.; Wilson, P. H.; Ballard, K.; Johnson, B. W.
10.1101/2024.08.11.607491 — neuroscience — Posted on 2024-08-12
3120 Genetic analysis of retinal cell types reveals synaptic pathology in schizophrenia
Boudriot, E.; Stephan, M.; Rabe, F.; Smigielski, L.; Schmitt, A.; Falkai, P.; Ziller, M. J.; Rossner, M. J.; Homan, P.; Papiol, S.; Raabe, F. J.
10.1101/2024.08.09.607343 — neuroscience — Posted on 2024-08-12
3121 KMT2A oncoproteins induce epigenetic resistance to targeted therapies
Janssens, D. H.; Duran, M.; Otto, D. J.; Wu, W.; Xu, Y.; Kirkey, D.; Mullighan, C. G.; Yi, J. S.; Meshinchi, S.; Sarthy, J. F.; Ahmad, K.; Henikoff, S.
10.1101/2023.12.29.573681 — cancer biology — Posted on 2024-08-12
3123 Simplified and Rapid Workflow Enhances Throughput of De Novo Sequencing of COVID-19 Neutralizing Antibodies
Xiong, Y.; Xiao, J.; Jiang, W.; Wang, J.; Bu, Q.; Chen, X.; Wu, Y.; Yu, R.; Yuan, Q.; Xia, N.
10.1101/2024.08.09.607349 — bioengineering — Posted on 2024-08-12
3124 Addressing the problem of lysine glycation prediction in proteins via Recurrent Neural Networks
Que-Salinas, U.; Martinez-Peon, D.; Mendez, G. M.; Arguelles-Lucho, P.; Reyes-Figueroa, A. D.; Scheckhuber, C. Q.
10.1101/2024.08.12.607666 — biochemistry — Posted on 2024-08-12
3125 Aerolysin nanopore structure revealed at high resolution in lipid environment
Anton, J.; Iacovache, I.; Bada Juarez, J. F.; Abriata, L.; Perrin, L.; Cao, C.; Marcaida, M. J.; Zuber, B.; Dal Peraro, M.
10.1101/2024.08.12.607338 — biochemistry — Posted on 2024-08-12
3126 High-coverage genome sequencing of Yayoi and Jomon individuals shed light on prehistoric human population history in East Eurasian
Ishiya, K.; Mizuno, F.; Gojobori, J.; Kumagai, M.; Taniguchi, Y.; Kondo, O.; Matsushita, M.; Matsushita, T.; Wang, L.; Kurosaki, K.; Ueda, S.
10.1101/2024.08.09.606917 — genomics — Posted on 2024-08-12
3132 Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins
Flick, H.; Venbakkam, A.; Singh, P. K.; Layish, B.; Huang, S.-W. K.; Radhakrishnan, R.; Kvaratskhelia, M.; Engelman, A. N.; Kane, M.
10.1101/2024.08.12.607676 — microbiology — Posted on 2024-08-12
3133 Commensal-derived short-chain fatty acids disrupt lipid membrane homeostasis in Staphylococcus aureus
Fletcher, J. R.; Hansen, L. A.; Martinez, R.; Freeman, C. D.; Thorns, N.; Villareal, A. R.; Penningroth, M. R.; Vogt, G. A.; Tyler, M.; Hines, K. M.; Hunter, R. C.
10.1101/2024.08.12.607382 — microbiology — Posted on 2024-08-12
3136 Pathogenic Th17 cells in arthritogenic mice share T cell receptor features with Wild-type Tregs
Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.
10.1101/2024.03.01.582868 — immunology — Posted on 2024-08-12
3137 Distinct T cell chromatin landscapes in scleroderma subtypes
Dou, D. R.; Zhao, Y.; Abe, B.; Li, R.; Zaba, L. C.; Aren, K.; Carns, M.; Chung, L. S.; Hinchcliff, M.; Chang, H. Y.
10.1101/2021.01.10.426131 — immunology — Posted on 2024-08-12
3138 Damage sensing through TLR9 Regulates Inflammatory and Antiviral Responses During Influenza Infection
Kim, J.; Yuan, Y.; Agaronyan, K.; Zhao, A.; Wang, V. D.; Gupta, G.; Essayas, H.; Kaminski, A.; McGovern, J.; Yu, S.; Woo, S.; Lee, C. J.; Gandhi, S.; Saber, T.; Saleh, T.; Hu, B.; Sun, Y.; Ishikawa, G.; Bain, W.; Evankovich, J.; Chen, L.; Yun, H.; Herzog, E.; Dela Cruz, C. S.; Ryu, C.; Sharma, L.
10.1101/2024.03.04.583378 — immunology — Posted on 2024-08-12
3141 A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat
Cornwell, B. R.; Didier, P. R.; Grogans, S. E.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Hur, J.; Scott, Z. S.; Fox, A. S.; DeYoung, K. A.; Smith, J. F.; Shackman, A. J.
10.1101/2024.07.10.602972 — neuroscience — Posted on 2024-08-12
3143 Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in Escherichia coli
Sotomayor, B.; Donahue, T. C.; Mahajan, S. P.; Taw, M. N.; Hulbert, S. W.; Bidstrup, E. J.; Owitipana, D. N.; Pang, A.; Yang, X.; Ghosal, S.; Alabi, C. A.; Azadi, P.; Gray, J. J.; Jewett, M. C.; Wang, L.-X.; DeLisa, M. P.
10.1101/2024.08.12.607630 — synthetic biology — Posted on 2024-08-12
3144 Chickpea NCR13 disulfide cross-linking variants exhibit profound differences in antifungal activity and modes of action
Godwin, J.; Djami-Tchatchou, A. T.; Velivelli, S. L. S.; Tetorya, M.; Kalunke, R.; Pokhrel, A.; Zhou, M.; Buchko, G. W.; Czymmek, K.; Shah, D.
10.1101/2024.08.09.607347 — plant biology — Posted on 2024-08-12
3148 Machine Learning to Predict Gut Microbiomes of Agricultural Pests
Jobayer, M.; Taylor, A.; Hasan, M. R.; Ahmed, K. A.; Hossain, M. Z.
10.1101/2024.08.12.607564 — bioinformatics — Posted on 2024-08-12
3149 ESPClust: Unsupervised identification of modifiers for the effect size profile in omics association studies
Perez-Reche, F. J.; Cheetham, N.; Bowyer, R.; Thompson, E. J.; Tettamanzi, F.; Menni, C.; Steves, C.
10.1101/2024.08.11.607486 — bioinformatics — Posted on 2024-08-12
3151 Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging
Tsai, Y.-T.; Seymen, N.; Thompson, I. R.; Zou, X.; Mumtaz, W.; Gerlevik, S.; Mufti, G. J.; Karimi, M. M.
10.1101/2024.02.09.579582 — genomics — Posted on 2024-08-12
3152 Bacterial ecology and evolution converge on seasonal and decadal scales
Rohwer, R. R.; Kirkpatrick, M.; Garcia, S. L.; Kellom, M.; McMahon, K. D.; Baker, B. J.
10.1101/2024.02.06.579087 — evolutionary biology — Posted on 2024-08-12
3154 Caspar specifies primordial germ cell count and identity in Drosophila melanogaster
Das, S.; Hegde, S.; Wagh, N.; Sudhakaran, J.; Roy, A. E.; Deshpande, G.; Ratnaparkhi, G. S.
10.1101/2024.04.25.591132 — developmental biology — Posted on 2024-08-12
3155 Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB
DeAngelo, J. D.; Maron, M. I.; Roth, J. S.; Silverstein, A. M.; Gupta, V.; Stransky, S.; Basken, J.; Azofeifa, J.; Sidoli, S.; Gamble, M. J.; Shechter, D.
10.1101/2024.08.09.607355 — molecular biology — Posted on 2024-08-12
3158 Laminin-defined Mechanical Status Modulates Retinal Pigment Epithelium Functionality
Kozyrina, A. N.; Piskova, T.; Semeraro, F.; Doolaar, I.; Prapty, T.; Haraszti, T.; Hubert, M.; Windoffer, R.; Leube, R. E.; Smith, A.-S.; Di Russo, J.
10.1101/2023.02.24.529913 — biophysics — Posted on 2024-08-12
3160 Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity
Cutler, R.; Corveleyn, L.; Ctortecka, C.; Cantlon, J.; Jacome Vaca, S. A.; Deforce, D.; Vijg, J.; Dhaenens, M.; Papanastasiou, M.; Carr, S. A.; Sidoli, S.
10.1101/2024.07.05.602213 — molecular biology — Posted on 2024-08-12
3163 Agency accounts for the effect of feedback transparency on motor imagery neurofeedback performance
Dussard, C.; Pillette, L.; Dumas, C.; Pierrieau, E.; Hugueville, L.; Lau, B.; Jeunet, C.; George, N.
10.1101/2024.02.27.582270 — neuroscience — Posted on 2024-08-12
3165 Delving into the claustrum: insights into memory formation, stabilization and updating in mice
Medina, C.; Ojea Ramos, S.; Depino, A. M.; Romano, A. G.; Krawczyk, M. C.; Boccia, M. M.
10.1101/2024.04.26.591314 — neuroscience — Posted on 2024-08-12
3167 Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma
Shema, E.; Griess, O.; Furth, N.; Harpaz, N.; Di Bernardo, N.; Salame, T. M.; Dassa, B.; Karagiannidis, I.; Isshiki, Y.; Gross, M.; Melnick, A. M.; Beguelin, W.; Ron, G.
10.1101/2024.08.05.606629 — cancer biology — Posted on 2024-08-12
3168 Plasmonic Enhancement of Protein Function
Locarno, M.; Dong, Q.; Meng, X.; Glessi, C.; Hettema, N.; Brandsma, N.; Blokhuizen, S.; Castaneda, A.; Ganapathy, S.; Post, M.; Schmidt, T.; van Roemburg, L.; Xu, B.; Cho, C.-T.; Laan, L.; Chien, M.-P.; Brinks, D.
10.1101/2024.02.07.579195 — biophysics — Posted on 2024-08-12
3170 Strategic acyl carrier protein engineering enables functional type II polyketide synthase reconstitution in vitro
Li, K. K.; Cho, Y. I.; Tran, M. A.; Wiedemann, C.; Zhang, S.; Koweek, R. S.; Hoang, N. K.; Hamrick, G.; Bowen, M.; Kokona, B.; Stallforth, P.; Beld, J.; Hellmich, U.; Charkoudian, L. K.
10.1101/2023.08.02.551649 — biochemistry — Posted on 2024-08-12
3171 Changes in the Public IgM Repertoire and its Idiotypic Connectivity in Alzheimer's Disease and Frontotemporal Dementia
Pashova-Dimov, S.; Petrov, P.; Karachanak-Yankova, S.; Belezhanska, D.; Zhelev, Y.; Mehrabian, S.; Traykov, L.; Pashov, A.
10.1101/2024.07.15.603559 — immunology — Posted on 2024-08-12
3172 CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
Li, E.; Benitez, C.; Boggess, S. C.; Koontz, M.; Rose, I. V. L.; Martinez, D.; Draeger, N.; Teter, O. M.; Samelson, A. J.; Pierce, N.; Ullian, E. M.; Kampmann, M.
10.1101/2023.04.26.538498 — neuroscience — Posted on 2024-08-12
3176 Scalable and universal prediction of cellular phenotypes
Ji, Y.; Tejada-Lapuerta, A.; Schmacke, N. A.; Zheng, Z.; Zhang, X.; Khan, S.; Rothenaigner, I.; Tschuck, J.; Hadian, K.; Theis, F. J.
10.1101/2024.08.12.607533 — cell biology — Posted on 2024-08-12
3178 Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation
Marchetti, T.; Milanesi, S.; Tintor, D.; Lorenzini, T.; Walser, S.; Vavassori, S.; Boyman, O.; Pachlopnik Schmid, J.
10.1101/2024.08.12.607544 — immunology — Posted on 2024-08-12
3181 Nonlinear progression during the occult transition establishes cancer lethality
Ginzel, J. D.; Chapman, H.; Sills, J. E.; Allen, E. J.; Barak, L. S.; Cardiff, R. D.; Borowsky, A. D.; Lyerly, H. K.; Rogers, B. W.; Snyder, J. C.
10.1101/2024.04.23.590826 — cancer biology — Posted on 2024-08-12
3183 DNA polymerase Lambda is anchored within the NHEJ synaptic complex via Ku70/80
Chaplin, A. K.; Frit, P.; Calsou, P.; Amin, H.; Hall, C.; Zahid, S.; Barboule, N.; Matharu, G.; Hardwick, S. W.; Chirgadze, D. Y.; Chauvat, J.; Britton, S.; Ropars, V.; Charbonnier, J.-B.
10.1101/2024.08.12.607588 — biochemistry — Posted on 2024-08-12
3184 Experimental evolution of gene essentiality in bacteria
Bao, L.; Zhu, Z.; Ismail, A.; Zhu, B.; Anandan, V.; Whiteley, M.; Kitten, T.; Xu, P.
10.1101/2024.07.16.600122 — evolutionary biology — Posted on 2024-08-12
3190 Loss of PI5P4Kalpha slows the progression of a Pten mutant basal cell model of prostate cancer
Triscott, J.; Lehner, M.; Benjak, A.; Reist, M.; Emerling, B. M.; Ng, C. K.; de Brot, S.; Rubin, M. A.
10.1101/2024.08.12.607541 — cancer biology — Posted on 2024-08-12
3191 Therapeutic Tumor Macrophage Reprogramming in Breast Cancer Through a Peptide-Drug Conjugate
Lepland, A.; Peranzoni, E.; Haljasorg, U.; Asciutto, E. K.; Crespi-Amer, M.; Modesti, L.; Kilk, K.; Lombardia, M.; Acosta, G.; Royo, M.; Peterson, P.; Marigo, I.; Teesalu, T.; Scodeller, P.
10.1101/2024.08.12.607575 — cancer biology — Posted on 2024-08-12
3194 RIOT - Rapid Immunoglobulin Overview Tool - annotation of nucleotide and amino acid immunoglobulin sequences using an open germline database.
Dudzic, P.; Janusz, B.; Satlawa, T.; Chomicz, D.; Gawlowski, T.; Grabowski, R.; Jozwiak, P.; Tarkowski, M.; Mycielski, M.; Wrobel, S.; Krawczyk, K.
10.1101/2024.08.12.607568 — bioinformatics — Posted on 2024-08-12
3195 Results of the Protein Engineering Tournament: An Open Science Benchmark for Protein Modeling and Design
Armer, C.; Kane, H.; Cortade, D. L.; Redestig, H.; Estell, D. A.; Yusuf, A.; Rollins, N. J.; Spinner, H.; Marks, D.; Brunette, T.; Kelly, P. J.; DeBenedictis, E.
10.1101/2024.08.12.606135 — bioengineering — Posted on 2024-08-12
3198 GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome
Roeselova, A.; Maslen, S. L.; He, J. Z.; Jurkeviciute, G.; Skehel, M.; Enchev, R. I.; Balchin, D.
10.1101/2024.08.12.607569 — biochemistry — Posted on 2024-08-12
3199 Lower degree of microsatellite instability in colorectal carcinomas from MSH6-associated Lynch syndrome patients
Helderman, N. C.; Strobel, F.; Bohaumilitzky, L.; Terlouw, D.; van der Werf-'t Lam, A.-S.; van Wezel, T.; Morreau, H.; von Knebel Doeberitz, M.; Nielsen, M.; Kloor, M.; Ahadova, A.
10.1101/2024.08.12.607570 — genetics — Posted on 2024-08-12
3200 DNA-PKcs Inhibition Improves Sequential Gene Insertion of the Full-Length CFTR cDNA in Airway Stem Cells
Stack, J. T.; Rayner, R. E.; Nouri, R.; Suarez, C. J.; Kim, S. H.; Kanke, K. L.; Vetter, T. A.; Cormet-Boyaka, E.; Vaidyanathan, S.
10.1101/2024.08.12.607571 — genetics — Posted on 2024-08-12
3205 E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1
Matlock, W.; Rodger, G.; Pritchard, E.; Colpus, M.; Kapel, N.; Barrett, L.; Morgan, M.; Oakley, S.; Hopkins, K. L.; Roohi, A.; Karageorgopoulos, D.; Avison, M. B.; Walker, A. S.; Lipworth, S.; Stoesser, N.
10.1101/2024.08.12.607562 — microbiology — Posted on 2024-08-12
3206 EEG-based analysis of intrinsic brain network function in chronic pain: Insights from a comprehensive multi-data set study
Bott, F. S.; Zebhauser, P. T.; Hohn, V. D.; Turgut, O.; May, E. S.; Tiemann, L.; Gil Avila, C.; Heitmann, H.; Nickel, M. M.; Day, M. A.; Adhia, D. B.; Ashar, Y. K.; Wager, T. D.; Granovsky, Y.; Yarnitsky, D.; Jensen, M. P.; Gross, J.; Ploner, M.
10.1101/2024.08.12.607584 — neuroscience — Posted on 2024-08-12
3207 Modelling inflammation-induced peripheral sensitization in a dish - more complex than expected?
Li, Y.; Lock, A.; Fedele, L.; Zebochin, I.; Sabate, A.; Siddle, M.; Cainarca, S.; Roederer, P.; Montag, K.; Tarroni, P.; Bruestle, O.; Shaw, T.; Taams, L.; Denk, F.
10.1101/2024.08.12.607558 — neuroscience — Posted on 2024-08-12
3212 Grape ripening speed slowed down using natural variation
Falginella, L.; Magris, G.; Castellarin, S. D.; Gambetta, G. A.; Matthews, M. A.; Morgante, M.; Di Gaspero, G.
10.1101/2024.08.12.607560 — plant biology — Posted on 2024-08-12
3215 SAFARI: Pangenome Alignment of Ancient DNA Using Purine/Pyrimidine Encodings
Rubin, J. D.; van Waaij, J.; Kraft, L. M.; Siren, J.; Sackett, P. W.; Renaud, G.
10.1101/2024.08.12.607489 — bioinformatics — Posted on 2024-08-12
3216 Machine Learning to Predict Gut Microbiomes of Agricultural Pests
Jobayer, M.; Taylor, A.; Hasan, M. R.; Ahmed, K. A.; Hossain, M. Z.
10.1101/2024.08.12.607564 — bioinformatics — Posted on 2024-08-12
3222 A biofilm-tropic Pseudomonas aeruginosa bacteriophage uses the exopolysaccharide Psl as receptor
Walton, B.; Abbodante, S.; Marshall, M. E.; Dobruchowska, J. M.; Alvi, A.; Gallagher, L. A.; Vallikat, N.; Zhang, Z.; Wozniak, D. J.; Yu, E. W.; Boons, G.-J.; Pearlman, E.; Rietsch, A.
10.1101/2024.08.12.607380 — microbiology — Posted on 2024-08-12
3223 Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation
Marchetti, T.; Milanesi, S.; Tintor, D.; Lorenzini, T.; Walser, S.; Vavassori, S.; Boyman, O.; Pachlopnik Schmid, J.
10.1101/2024.08.12.607544 — immunology — Posted on 2024-08-12
3224 The role of TRPV4 in acute sleep deprivation-induced fear memory impairment
Guo, M.; Zhang, F.; Liu, S.; Zhang, Y.; Wang, L.; Song, J.; Wei, W.; Li, X.
10.1101/2024.08.12.607531 — neuroscience — Posted on 2024-08-12
3226 A posture subspace in primary motor cortex
Marino, P. J.; Bahureksa, L.; Fernandez Fisac, C.; Oby, E. R.; Smoulder, A. L.; Motiwala, A.; Degenhart, A. D.; Grigsby, E. M.; Joiner, W. M.; Chase, S. M.; Yu, B. M.; Batista, A. P.
10.1101/2024.08.12.607361 — neuroscience — Posted on 2024-08-12
3228 Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress
Nhung, T. T. M.; Phat, N. K.; Anh, T. T.; Nghi, T. D.; Thu, N. Q.; Lee, A.; Tien, N. T. N.; Anh, N. K.; Kim, K.; Nguyen, D. N.; Kim, D. H.; Park, S. K.; Long, N. P.
10.1101/2024.08.12.607527 — pharmacology and toxicology — Posted on 2024-08-12
3229 Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukaemia.
Lewis, A. C.; Gruber, E.; Franich, R.; Armstrong, J.; Kelly, M. J.; Opazo, C. M.; Mawal, C. H.; Birrell, A.; So, J.; Ting, K.; Brown, F.; Wei, A. H.; Powell, J. A.; Brown, K. K.; Johnstone, R. W.; Kats, L. M.
10.1101/2024.08.11.607520 — cancer biology — Posted on 2024-08-12
3233 HSV-1 infection induces a downstream-shift of the +1 nucleosome
Weiss, E.; Whisnant, A. W.; Hennig, T.; Djakovic, L.; Doelken, L.; Friedel, C. C.
10.1101/2024.03.06.583707 — bioinformatics — Posted on 2024-08-12
3237 OzWheat: a genome-to-phenome platform to resolve complex traits for wheat pre-breeding and research.
Hyles, J. E.; Eagles, H. A.; Ramm, K.; Sherman, B.; Gock, A.; Stops, S.; Phongkham, T.; Leyne, E.; Rathjen, T.; Suchecki, R.; Stevens, L. E.; Ord, L.; Fradgley, N. S.; McNeil, M. D.; Marquardt, A.; Andrew, S. C.; Forrest, K.; Eastwood, R. F.; Norman, A.; Tredrea, A.; Trethowan, R.; Trevaskis, B.; Dillon, S. K.
10.1101/2024.08.11.603522 — genomics — Posted on 2024-08-12
3238 Exploring adaptive introgression in modern human circadian rhythm genes
Kendall, C.; Nooranikhojasteh, A.; Debortoli, G.; Caue Furlan Roberto, V.; Mendes, M.; Samson, D.; Parra, E.; Viola, B.; Schillaci, M.
10.1101/2024.08.12.607550 — genomics — Posted on 2024-08-12
3240 Recurrent sex chromosome turn-over in termites
Fraser, R.; Moraa, R.; Djolai, A.; Meisenheimer, N.; Laube, S.; Vicoso, B.; Huylmans, A. K.
10.1101/2024.08.12.607539 — evolutionary biology — Posted on 2024-08-12
3241 Diverse somatic Transformer and sex chromosome karyotype pathways regulate gene expression in Drosophila gonad development
Mahadevaraju, S.; Pal, S.; Bhaskar, P.; McDonald, B.; Benner, L.; Denti, L.; Cozzi, D.; Bonizzoni, P.; Przytycka, T.; Oliver, B.
10.1101/2024.08.12.607556 — developmental biology — Posted on 2024-08-12
3242 The primary sclerosing cholangitis and ulcerative colitis colonic mucosa defined through paired microbial and single-cell RNA sequencing
Tearle, J. L. E.; Zhang, F.; Jackson, K. J. L.; Malhotra, P.; Tavakoli, P.; Koentgen, S.; Warren, J.; Williams, C.; Haque, A.; Arzivian, A.; Tedla, N.; Kim, A.; King, H. W.; Hold, G. L.; Ghaly, S.; James, K. R.
10.1101/2024.08.12.607536 — cell biology — Posted on 2024-08-12
3248 Local Synthesis of Reticulon-1C Lessens the Outgrowth of Injured Axons by Controlling Spastin Activity
Luarte, A.; Gallardo, J.; Corvalan, D.; Chakraborty, A.; Gouveia-Roque, C.; Bertin, F.; Contreras, C.; Ramirez, J. P.; Weber, A.; Acevedo, W.; Zuschratter, W.; Herrera, R.; Wyneken, U.; Paula Lima, A.; Adasme, T.; Figueroa, A.; Gonzalez, C.; Gonzalez-Billault, C.; Hengst, U.; Couve, A.
10.1101/2024.08.11.607514 — neuroscience — Posted on 2024-08-12
3251 Functional Electrical Stimulation and Brain-Machine Interfaces for Simultaneous Control of Wrist and Finger Flexion
Mender, M. J.; Ward, A. L.; Cubillos, L. H.; Kelberman, M. M.; Costello, J. T.; Temmar, H.; Wallace, D. M.; Lin, E. T.; Lam, J. L. W.; Willsey, M. S.; Ganesh Kumar, N.; Kung, T. A.; Patil, P. G.; Chestek, C. A.
10.1101/2024.08.11.607263 — neuroscience — Posted on 2024-08-12
3253 Unraveling lncRNA Diversity at a Single Cell Resolution and in a Spatial Context across Different Cancer Types
Prakrithi, P.; Vo, T.; Vu, H.; Xiong, A.; Nguyen, L. T.; Newman, A.; Whitehall, V.; Gonzalez Cruz, J. L.; Gupta, I.; Nguyen, Q.
10.1101/2024.08.12.607523 — cancer biology — Posted on 2024-08-12
3254 Transcriptomic alterations including p53 pathway dysregulation prime DNMT3A mutant cells for transformation
Lawrence, E.; Cooray, A.; Kueh, A.; Pal, M.; Tai, L.; Garnham, A.; Li-Wai-Suen, C. S. N.; Vanyai, H.; Gouil, Q.; Lancaster, J.; Callegari, S.; Whelan, L.; Lieschke, E.; Thomas, A.; Strasser, A.; Liao, Y.; Shi, W.; Wei, A.; Herold, M. J.
10.1101/2024.08.12.607467 — cancer biology — Posted on 2024-08-12
3255 Ferroptosis susceptibility of melanoma cells: dependence on cell-type, acquired drug resistance, and medium composition
Preis, J. R.; Rolvering, C.; Kirchmeyer, M.; Halilovic, D.; Wroblewska, J. P.; Tolle, F.; Behrmann, I.; Haan, C.
10.1101/2024.08.12.607529 — cancer biology — Posted on 2024-08-12
3257 CaMutQC: An R Package for Integrative Quality Control of Cancer Somatic Mutations
Wang, X.; Jiang, T.; Shen, A.; Chen, Y.; Zhou, Y.; Liu, J.; Zhao, S.; Chen, S.; Ren, J.; Zhao, Q.
10.1101/2024.08.12.606123 — bioinformatics — Posted on 2024-08-12
3259 Identification of a novel resistance gene which provides insight into Vip3Aa mode of action in Helicoverpa armigera
Bachler, A.; Padovan, A.; Anderson, C. J.; Wei, Y.; Wu, Y.; Pearce, S.; Downes, S.; James, B.; Tessnow, A.; Sword, G. A.; Williams, M.; Tay, W. T.; Gordon, K. H. J.; Walsh, T. K.
10.1101/2024.08.11.607516 — genomics — Posted on 2024-08-12
3263 Incoherent collective cell chemotaxis underlies organ dysmorphia in a model of branchio-oto-renal syndrome
Borges, A.; Pinto Teixeira, F.; Wibowo, I.; Hammerschmidt, M.; Kawakami, K.; Miranda Rodriguez, J. R.; Lopez-Schier, H.
10.1101/2021.01.27.428404 — developmental biology — Posted on 2024-08-12
3264 Scalable and universal prediction of cellular phenotypes
Ji, Y.; Tejada-Lapuerta, A.; Schmacke, N. A.; Zheng, Z.; Zhang, X.; Khan, S.; Rothenaigner, I.; Tschuck, J.; Hadian, K.; Theis, F. J.
10.1101/2024.08.12.607533 — cell biology — Posted on 2024-08-12
3266 YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges
Shi, Z.; Wen, K.; Zou, Z.; Fu, W.; Guo, K.; Sammudin, N. H.; Ruan, X.; Sullere, S.; Wang, S.; Zhang, X.; Thinakaran, G.; He, C.; Zhuang, X.
10.1101/2024.08.07.607063 — neuroscience — Posted on 2024-08-12
3267 When visual attention is divided in the flash-lag effect
Yook, J.; Hogendoorn, H.; Fink, G. R.; Vossel, S.; Weidner, R.
10.1101/2024.03.14.585092 — neuroscience — Posted on 2024-08-12
3268 T-Cell-Mediated Killing in Glioblastoma Organoids induced by Adenoviral Delivery of the CIITA Transgene
Salvato, I.; Klein, E.; Poli, A.; Rezaeipour, M.; Ermini, L.; Nosirov, B.; Lipsa, A.; Oudin, A.; Baus, V.; Dore, G. M.; Cosma, A.; Golebiewska, A.; Marchini, A.; Niclou, S. P.
10.1101/2024.01.22.576747 — cancer biology — Posted on 2024-08-12
3270 Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs
Garcia Guerra, A.; Sathyaprakash, C.; de Jong, O. G.; Lim, W.; Vader, P.; EL Andaloussi, S.; Bath, J.; Reine, J.; Aoki, Y.; Turberfield, A.; Wood, M.; Rinaldi, C.
10.1101/2024.08.09.605335 — bioengineering — Posted on 2024-08-12
3272 Delineating In-Vivo T1-Weighted Intensity Profiles Within the Human Insula Cortex Using 7-Tesla MRI
Dalby, C.; Dibble, A. J.; Carvalheiro, J.; Queirazza, F.; Sevegnani, M.; Harvey, M.; Svanera, M.; Fracasso, A.
10.1101/2024.08.05.605123 — neuroscience — Posted on 2024-08-12
3273 Surface lipids in nematodes are developmentally dependent and species-specific
Kotowska, A. M.; Hiramatsu, F.; Alexander, M. R.; Scurr, D. J.; Lightfoot, J. W.; Chauhan, V. M.
10.1101/2024.04.24.590549 — systems biology — Posted on 2024-08-12
3274 Sexually antagonistic co-evolution can explain female display signals and male sensory adaptations.
Wiberg, R. A. W.; Murray, R. L.; Herridge, E.; Parssinen, V.; Gwynne, D. T.; Bussiere, L. F.
10.1101/2022.03.14.484300 — evolutionary biology — Posted on 2024-08-12
3275 Evidence for deliberate burial of the dead by Homo naledi
Berger, L. R.; Makhubela, T.; Molopyane, K.; Kruger, A.; Randolph-Quinney, P.; Elliott, M.; Peixotto, B.; Fuentes, A.; Tafforeau, P.; Beyrand, V.; Dollman, K.; Jinnah, Z.; Brewer Gillham, A.; Broad, K.; Brophy, J.; Chinamatira, G.; Dirks, P.; Feuerriegel, E.; Gurtov, A.; Hlophe, N.; Hunter, L.; Hunte, R.; Jakata, K.; Jaskolski, C.; Morris, H.; Pryor, E.; Ramaphela, M.; Roberts, E.; Smilg, J.; Tsikoane, M.; Tucker, S.; van Rooyen, D.; Warren, K.; Wren, C.; Kissel, M.; Spikins, P.; Hawks, J.
10.1101/2023.06.01.543127 — paleontology — Posted on 2024-08-12
3279 Formation of brain-wide neural geometry during visual item recognition in monkeys
Chen, H.; Kunimatsu, J.; Oya, T.; Imaizumi, Y.; Hori, Y.; Matsumoto, M.; Tsubo, Y.; Hikosaka, O.; Minamimoto, T.; Naya, Y.; Yamada, H.
10.1101/2024.08.05.604527 — neuroscience — Posted on 2024-08-11
3280 Relative phase of distributed oscillatory dynamics implements a working memory in a simple brain
Dunn, R. L.; Costello, C.; Borchardt, J. M.; Sprague, D. Y.; Chiu, G. C.; Miller, J. M.; L'Etoile, N.; Kato, S.
10.1101/2024.08.11.607402 — neuroscience — Posted on 2024-08-11
3286 A framework for quality control in quantitative proteomics
Tsantilas, K. A.; Merrihew, G. E.; Robbins, J. E.; Johnson, R. S.; Park, J.; Plubell, D. L.; Canterbury, J. D.; Huang, E.; Riffle, M.; Sharma, V.; MacLean, B. X.; Eckels, J.; Wu, C. C.; Bereman, M. S.; Spencer, S. E.; Hoofnagle, A. N.; MacCoss, M. J.
10.1101/2024.04.12.589318 — biochemistry — Posted on 2024-08-11
3287 Methods for detection of cardiac glycogen-autophagy
Koutsifeli, P.; Daniels, L. J.; Neale, J. P. H.; Fong, S.; Varma, U.; Annandale, M.; Li, X.; Nursalim, Y.; Bell, J. R.; Weeks, K. L.; Stotland, A.; Taylor, D. J.; Gottlieb, R. A.; Delbridge, L. M. D.; Mellor, K. M.
10.1101/2024.08.11.607511 — molecular biology — Posted on 2024-08-11
3288 AmygdalaGo-BOLT3D: A boundary learning transformer for tracing human amygdala
Dong, B.; Zhou, Q.; Gao, P.; Jintao, W.; Xiao, J.; Wang, W.; Liang, P.; Lin, D.; He, H.; Zuo, X.-N.
10.1101/2024.08.11.607487 — neuroscience — Posted on 2024-08-11
3290 A Self-Assembling Immune-Featured Osteosarcoma Patient/PDX Derived Organoid Model and Biobank for Personalized Immune Therapy
Mu, H.; Tao, Y.; Wang, J.; He, X.; Zhang, Q.; Chen, W.; Yao, B.; Ding, S.; Yang, X.; Zhang, L.; Wang, H.; Zuo, D.; Shen, J.; Sun, M.; Wang, H.; Jiao, M.; Jin, X.; Jin, Y.; Liang, Y.; Gong, Y.; Mao, W.; Liu, Q.; Wang, Z.; Lv, Y.; Xu, J.; Zhang, T.; Yang, Y.; Lin, J.; Asward, F. J.; Joseph, J. D.; Li, M.; Cai, Z.; Sun, W.; Yang, L.; Hua, Y.
10.1101/2024.08.11.607471 — cancer biology — Posted on 2024-08-11
3291 Faster amylin aggregation on fibrillar collagen hastens diabetic progression through β cell death and loss of function
Hazari, M. A.; Kannan, G.; Jha, A. K.; Pavan, M. K.; Dasgupta, S.; Sultana, F.; Pujahari, S. R.; Singh, S.; Dutta, S.; Pydi, S. P.; Dutta, S.; Bhaumik, P.; Zafar, H.; Kumar, A.; Sen, S.
10.1101/2024.08.10.607320 — biophysics — Posted on 2024-08-11
3294 Predicting the translation efficiency of messenger RNA in mammalian cells
Zheng, D.; Wang, J.; Persyn, L.; Liu, Y.; Montoya, F. U.; Cenik, C.; Agarwal, V.
10.1101/2024.08.11.607362 — bioinformatics — Posted on 2024-08-11
3295 Translation efficiency covariation across cell types is a conserved organizing principle of mammalian transcriptomes
Liu, Y.; Hoskins, I.; Geng, M.; Zhao, Q.; Chacko, J.; Qi, K.; Persyn, L.; Wang, J.; Zheng, D.; Zhong, Y.; Rao, S.; Park, D.; Cenik, E. S.; Agarwal, V.; Ozadam, H.; Cenik, C.
10.1101/2024.08.11.607360 — bioinformatics — Posted on 2024-08-11
3296 Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling
Mcleod, J. C.; Lim, C.; Stokes, T.; Sharif, J.-A.; Zeynalli, V.; Wiens, L.; D'Souza, A. C.; Colenso-Semple, L.; McKendry, J.; Morton, R. W.; Mitchell, C. J.; Oikawa, S. Y.; Wahlestedt, C.; Chapple, P.; McGlory, C.; Timmons, J. A.; Phillips, S. M.
10.1101/2024.08.11.606848 — bioinformatics — Posted on 2024-08-11
3297 3D printed microtissue cassettes enabling high throughput proton radiobiological assays
Yang, C.-T.; Cho, I.-C.; Yu, C.-F.; Cheah, E.; Liu, T.; Lin, Y.-P.; Yu, S.; Jheng, J.-W.; Kempson, I.; Chao, T.-C.; Lee, S.-H.; Bezak, E.; Thierry, B.
10.1101/2024.08.10.607473 — bioengineering — Posted on 2024-08-11
3298 Characterization of a marine bacteria through a novel metabologenomics approach
Arini, G.; Borelli, T. C.; Ferreira, E. G.; de Felicio, R.; Rezende-Teixeira, P.; Goncalves, M. P.; Oliveira, F. R.; de Siqueira, G. V.; Mencucini, L. G.; Tsuji, H.; Andrade, L. S. N.; Garrido, L.; Padilla, G.; Gil-de-la-Fuentes, A.; Wang, M.; Lopes, N. P.; Trivella, D. B.; Costa-Lotufo, L. V.; Guazzaroni, M.-E.; da Silva, R. R.
10.1101/2024.08.11.607463 — biochemistry — Posted on 2024-08-11
3299 Mechanism of Co-Transcriptional Cap-Snatching by Influenza Polymerase
Rotsch, A. H.; Li, D.; Dupont, M.; Krischuns, T.; Oberthuer, C.; Stelfox, A.; Lukarska, M.; Fianu, I.; Lidschreiber, M.; Naffakh, N.; Dienemann, C.; Cusack, S.; Cramer, P.
10.1101/2024.08.11.607481 — biochemistry — Posted on 2024-08-11
3300 Exploiting functional regions in the viral RNA genome as druggable entities
Wei, D.; Luo, D.; Zheng, Y.; Huang, Z.; Wen, Z.; Guo, L.; Deng, Y.; Li, Q.; Bai, Y.; Haider, S.; Parkinson, G. N.
10.1101/2024.08.11.607475 — genomics — Posted on 2024-08-11
3302 Adversarial learning enables unbiased organism-wide cross-species alignment of single-cell RNA data
Cooper, S.; Diaz-Mejia, J. J.; Innes, B.; Williams, E.; Mendonca, D.; Focsa, O.; Nixon, A.; Singh, S.; Schuster, R.; Hinz, B.; Buechler, M.
10.1101/2024.08.11.607498 — genetics — Posted on 2024-08-11
3306 Rapid depletion and super-resolution microscopy reveal an unexpected role of the nuclear-speckle protein SRSF5 in paraspeckle assembly and dynamics during cellular stress
Arnold, B.; Kessler, L.; Okuda, E. K.; Rieger, R. R.; Canas, M. C. H.; Zebrowska, E.; Bakisoglu, C.; Nagasse, H. Y.; Stanek, D.; Dormann, D.; Zarnack, K.; Heilemann, M.; Mueller-McNicoll, M.
10.1101/2024.08.11.607506 — cell biology — Posted on 2024-08-11
3308 An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm
Kruse, A.; Schneider, S.; Merges, G. E.; Froebius, A. C.; Forne, I.; Imhof, A.; Schorle, H.; Steger, K.
10.1101/2024.08.11.606797 — molecular biology — Posted on 2024-08-11
3309 B cells targeting parasites capture spatially linked antigens to secure T cell help
Gao, X.; McNamara, H. A.; Lee, J.; Lo, A. F.; Chatterjee, D.; Spensberger, D.; Fernandez-Ruiz, D.; Walz, K.; Wang, K.; Kelly, H. G.; Pohl, K.; Carreira, P. E.; Do, A.; Xiong, L.; Beattie, L.; Spencer, A. J.; Gray, D. H.; Frischknecht, F.; Rug, M.; Cockburn, I. A.
10.1101/2024.08.10.607257 — immunology — Posted on 2024-08-11
3310 Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signalling
Xu, C.; Obers, A.; Qin, M.; Brandli, A.; Wong, J.; Huang, X.; Clatch, A.; Fayed, A.; Starkey, G.; DCosta, R.; Gordon, C. L.; Beattie, L.; Mackay, L. K.; Godfrey, D. I.; Koay, H.-F.
10.1101/2024.08.11.607476 — immunology — Posted on 2024-08-11
3311 EMMPRIN confers metabolic advantage for monocytes and macrophages to promote disease in a model of multiple sclerosis
Kaushik, D.; Das, A.; Silva, C.; D'Mello, C.; Almeida, L. G. N.; Ghasemi, N.; Neri, P.; Dufour, A.; Bahlis, N. J.; Xue, M.; Yong, V. W.
10.1101/2024.08.11.607460 — immunology — Posted on 2024-08-11
3312 Neural Sequences Underlying Directed Turning in C. elegans
Kramer, T. S.; Wan, F. K.; Pugliese, S. M.; Atanas, A. A.; Hiser, A. W.; Luo, J.; Bueno, E.; Flavell, S. W.
10.1101/2024.08.11.607076 — neuroscience — Posted on 2024-08-11
3316 A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D
Villegas-Valencia, M.; Stark, M. R.; Seger, M.; Wellman, G. B.; Overmans, S.; Lammers, P. J.; Rader, S. D.; Lauersen, K. J.
10.1101/2024.07.30.605877 — bioengineering — Posted on 2024-08-11
3318 Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway
Isotani, R.; Igarashi, M.; Miura, M.; Naruse, K.; Kuranami, S.; Katoh, M.; Nomura, S.; Yamauchi, T.
10.1101/2024.01.02.573853 — cell biology — Posted on 2024-08-11
3321 Reward history cues focal attention in whisker somatosensory cortex
Ramamurthy, D. L.; Rodriguez, L.; Cen, C.; Li, S.; Chen, A.; Feldman, D. E.
10.1101/2024.07.17.603927 — neuroscience — Posted on 2024-08-11
3322 Secure and Federated Genome-Wide Association Studies for Biobank-Scale Datasets
Cho, H.; Froelicher, D.; Chen, J.; Edupalli, M.; Pyrgelis, A.; Troncoso-Pastoriza, J. R.; Hubaux, J.-P.; Berger, B.
10.1101/2022.11.30.518537 — bioinformatics — Posted on 2024-08-10
3323 Efficient clustering of large molecular libraries
Jung, V.; Lopez Perez, K.; Chen, L.; Huddleston, K.; Miranda Quintana, R. A.
10.1101/2024.08.10.607459 — bioinformatics — Posted on 2024-08-10
3326 H3K36 Methylation - a Guardian of Epigenome Integrity
Shipman, G.; Padilla, R.; Horth, C.; Bareke, E.; Majewski, J.
10.1101/2024.08.10.607446 — genomics — Posted on 2024-08-10
3328 Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation
Momin, N.; Pabel, S.; Rudra, A.; Kumowski, N.; Lee, I.-H.; Mentkowski, K.; Yamazoe, M.; Stengel, L.; Muse, C. G.; Seung, H.; Paccalet, A.; Gonzalez-Correa, C.; Jacobs, E. B.; Grune, J.; Schloss, M. J.; Sossalla, S.; Wojtkiewicz, G.; Iwamoto, Y.; McMullen, P.; Mitchell, R. N.; Ellinor, P. T.; Anderson, D. G.; Naxerova, K.; Nahrendorf, M.; Hulsmans, M.
10.1101/2024.08.10.607461 — immunology — Posted on 2024-08-10
3332 Emergence of power-law distributions in protein-protein interaction networks through study bias
Blumenthal, D. B.; Lucchetta, M.; Kleist, L.; Fekete, S. P.; List, M.; Schaefer, M. H.
10.1101/2023.03.17.533165 — systems biology — Posted on 2024-08-10
3333 {Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes}
Chowdhury, J. M.; Chacin Ruiz, E. A.; Ohr, M. P.; Swindle-Reilly, K. E.; Ford Versypt, A. N.
10.1101/2023.05.05.539491 — systems biology — Posted on 2024-08-10
3334 A Multiomic Analysis Reveals How Breast Cancers Disseminated to the Bone Marrow Acquire Aggressive Phenotypes through Tumor-Stroma Tunnels
Sinha, S.; Callow, B.; Farfel, A.; Roy, S.; Chen, S.; Rajendran, S.; Buschhaus, J.; Luker, K. E.; Ghosh, P.; Luker, G. D.
10.1101/2023.03.18.533175 — cancer biology — Posted on 2024-08-10
3335 MyVivarium: A cloud-based lab animal colony management application with near-realtime ambient sensing
Vidva, R.; Raza, M. A.; Prabhakaran, J.; Sheikh, A.; Sharp, A.; Ott, H.; Moore, A.; Fleisher, C.; Pitychoutis, P. M.; Nguyen, T. V.; Sathyanesan, A.
10.1101/2024.08.10.607395 — bioinformatics — Posted on 2024-08-10
3340 Long-read transcriptomic identification of synaptic adaptation to amyloid pathology in the App(NL-G-F) knock-in mouse model of the earliest phase of Alzheimer's disease
Yaman, U.; Banks, G.; Gustavsson, E. K.; Mumford, P.; Magusali, N.; Taso, O. S.; Macpherson, H.; Carmona, S.; Murray, M.; Bains, R. S.; Forrest, H.; Stewart, M.; Scott, C.; Lipina, T. V.; Cheng, Z.; Tierney, A. L.; Unwin, R. D.; Botia, J. A.; Sala Frigerio, C.; Wells, S. E.; Hardy, J.; Soreq, L.; Wiseman, F. K.; Salih, D. A.
10.1101/2024.08.10.607237 — genetics — Posted on 2024-08-10
3341 Self-organizing ovarian somatic organoids preserve cellular heterogeneity and reveal cellular contributions to ovarian aging
Dipali, S. S.; Gowett, M. Q.; Kamat, P.; Converse, A.; Zaniker, E. J.; Fennell, A.; Chou, T.; Pritchard, M. T.; Zelinski, M.; Phillip, J. M.; Duncan, F. E.
10.1101/2024.08.10.607456 — cell biology — Posted on 2024-08-10
3342 Eosinophils protect against SARS-CoV-2 following a vaccine breakthrough infection
Moore, K. M.; Foster, S. L.; Elrod, E. J.; Floyd, K. A.; Williams, M. E.; Kar, M.; Vander Velden, J.; Ellis, M.; Malik, A.; Wali, B.; Lapp, S.; Metz, A.; Bosinger, S. E.; Seder, R. A.; Amara, R. R.; Menachery, V. D.; Kohlmeier, J. E.; Grakoui, A.; Suthar, M. S.
10.1101/2024.08.08.607190 — immunology — Posted on 2024-08-10
3344 A pan-variant miniprotein inhibitor protects against SARS-CoV-2 variants
Lee, J.; Case, J. B.; Ravichandran, R.; Asarnow, D.; Tortorici, M. A.; Brown, J. T.; Sanapala, S.; Carter, L.; Baker, D.; Diamond, M. S.; Veesler, D.
10.1101/2024.08.08.606885 — biochemistry — Posted on 2024-08-10
3345 Single cell RNA sequencing reveals a shift in cell function and maturation of endogenous and infiltrating cell types in response to acute intervertebral disc injury
Clayton, S. W.; Sebastian, A.; Wilson, S. P.; Hum, N. R.; Walk, R. E.; Easson, G. W.; Vaidya, R. S.; Broz, K. S.; Loots, G. G.; Tang, S. Y.
10.1101/2024.08.10.607363 — cell biology — Posted on 2024-08-10
3347 A Refined Analysis of Neanderthal-Introgressed Sequences in Modern Humans with a Complete Reference Genome
Liang, S.-A.; Ren, T.; Zhang, J.; He, J.; Wang, X.; Jiang, X.; He, Y.; McCoy, R. C.; Fu, Q.; Akey, J. M.; Mao, Y.; Chen, L.
10.1101/2024.08.09.607285 — evolutionary biology — Posted on 2024-08-10
3348 YAP charge patterning mediates signal integration through transcriptional co-condensates
Meyer, K.; Yserentant, K.; Cheloor-Kovilakam, R.; Ruff, K. M.; Chung, C.-I.; Shu, X.; Huang, B.; Weiner, O. D.
10.1101/2024.08.10.607443 — cell biology — Posted on 2024-08-10
3349 taxmyPHAGE: Automated taxonomy of dsDNA phage genomes at the genus and species
Millard, A. D.; Denise, R.; Lestido, M.; Thomas, M.; Webster, D.; Turner, D.; Sicheritz-Ponten, T.
10.1101/2024.08.09.606593 — microbiology — Posted on 2024-08-10
3354 Rpt5 encodes a receptor-like protein that provides broad and effective net form net blotch (Pyrenophora teres f. teres) resistance in barley
Effertz, K.; Richards, J. K.; Clare, S. J.; del Castillo, M.; Sharma Poudel, R.; Li, M.; Zhang, J.; Moscou, M. J.; Friesen, T.; Brueggeman, R. S.
10.1101/2024.08.09.607401 — plant biology — Posted on 2024-08-10
3355 The SH Protein of Mumps Virus is a Druggable Pentameric Viroporin
Devantier, K.; Toft-Bertelsen, T. L.; Prestel, A.; Kjaer, V. M. S.; Sahin, C.; Giulini, M.; Louka, S.; Spiess, K.; Manandhar, A.; Qvortrup, K.; Ulven, T.; Bentzen, B. H.; Bonvin, A.; MacAulay, N.; Kragelund, B. B.; Rosenkilde, M. M.
10.1101/2024.08.09.607002 — biophysics — Posted on 2024-08-10
3359 Comprehensive assembly of monoclonal and mixed antibody sequences
Jiang, W.; Xiong, Y.; Xiao, J.; Wang, J.; Jiang, Z.; Luo, L.; Yuan, Q.; Xia, N.; Yu, R.
10.1101/2024.08.09.607415 — bioinformatics — Posted on 2024-08-10
3361 Local photo-crosslinking of native tissue matrix regulates cell function
Ahmed, D. W.; Tan, M. L.; Gabbard, J.; Liu, Y.; Hu, M. M.; Stevens, M.; Midekssa, F. S.; Han, L.; Zemans, R. L.; Baker, B.; Loebel, C.
10.1101/2024.08.10.607417 — bioengineering — Posted on 2024-08-10
3365 Human rod photoreceptor outer segments are supported by accessory inner segment structures
Lewis, T. R.; Klementieva, N. V.; Phan, S.; Castillo, C. M.; Kim, K.-Y.; Cao, L. Y.; Ellisman, M.; Arshavsky, V. Y.; Alekseev, O.
10.1101/2024.08.09.607370 — cell biology — Posted on 2024-08-10
3366 The eduWOSM: an advanced optical microscope for education
Carter, N. J.; Martin, D. S.; Molloy, J. E.; Cross, R. A.
10.1101/2024.08.10.607181 — cell biology — Posted on 2024-08-10
3370 Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB
DeAngelo, J. D.; Maron, M. I.; Roth, J. S.; Silverstein, A. M.; Gupta, V.; Stransky, S.; Azofeifa, J.; Sidoli, S.; Gamble, M. J.; Shechter, D.
10.1101/2024.08.09.607355 — molecular biology — Posted on 2024-08-10
3373 Prediction of symptomatic and asymptomatic bacteriuria in spinal cord injury patients using machine learning
Hoque, M. M.; Noorian, P.; Espinoza-Vergara, G.; To, J.; Leo, D.; Chari, P.; Weber, G.; Pryor, J.; Duggin, I. G.; Lee, B. B.; Rice, S. A.; McDougald, D.
10.1101/2024.08.09.607254 — microbiology — Posted on 2024-08-10
3374 In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity
Hagan, N. B.; Inaku, C.; Kunder, N.; White, T.; Iraguha, T.; Meyer, A.; Pauken, K.; Schenkel, J. M.
10.1101/2024.08.10.607414 — immunology — Posted on 2024-08-10
3375 Dynamic roles of ILC3 in endometrial repair and regeneration
Cuff, A. O.; Woon, E. V.; Bainton, T.; Browne, B.; Kirkwood, P. M.; Collins, F.; Gibson, D. A.; Saunders, P.; Horne, A. W.; Johnson, M. R.; MacIntyre, D. A.; Male, V.
10.1101/2024.08.10.606309 — immunology — Posted on 2024-08-10
3376 Type I TARPs regulate Kv7.2 potassium channels andsusceptibility to seizures
Ventura Rodrigues, M. V.; Inacio, A. S.; Soldovieri, M. V.; Ribau, S.; Leal, T. M.; Baurberg, T.; Mosca, I.; Ambrosino, P.; Amado, L.; Beltrao, N.; Caldeira, G. L.; Ribeiro, L. F.; Li, K. W.; Groc, L.; Ferreira, J. S.; Taglialatela, M.; Carvalho, A. L.
10.1101/2024.08.09.607194 — neuroscience — Posted on 2024-08-10
3379 Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes
Okeoma, C. M.; Naushad, W.; Okeoma, B. C.; Gartner, C.; Santos Ortega, Y.; Vary, C.; Carregari, V. C.; Larsen, M. R.; Grassi-Oliveira, R.; Walss-Bass, C.
10.1101/2024.08.09.607388 — neuroscience — Posted on 2024-08-10
3382 Systemic identification of functionally conserved lncRNA metabolic regulators in human and mouse livers
Jiang, C.; Li, Z.; Li, P.; Ma, Y.; Seok, S.; Podguski, S.; Moturi, S.; Yoneda, N.; Kawai, K.; Uehara, S.; Ohnishi, Y.; Suemizu, H.; Zhang, J.; Cao, H.
10.1101/2024.08.10.607444 — physiology — Posted on 2024-08-10
3383 Hematobiochemical Alterations and Lesion Characterization Caused by Fasciolosis in Cattle Slaughtered at Gondar ELFORA Abattoir, Ethiopia
Temesgen, A. B.; Mitiku, T.; Birhan, M.; Kebede, M. C.; Yesuf, M.; Yayeh, M.; Alemayehu, M. M.; Anagaw, B.; Geda, A. M.; Tumebo, A. W.; Shiferaw, K. A.; Wassie, Z. G.; Berie, G. K.; Mengistu, B. A.; Feleke, M. G.; Edenshaw, F.; Yitie, M. T.; Kasse, G. E.; Melkamu, E.
10.1101/2024.08.10.607441 — pathology — Posted on 2024-08-10
3384 Triple Negative Breast Cancer Cells Acquire Lymphocyte Proteins and Genomic DNA During Trogocytosis with T Cells
Sivakoses, A.; Marcarian, H. Q.; Arias, A. M.; Lam, A. R.; Ihedioha, O. C.; Santamaria, J. A.; Gurtner, G. C.; Bothwell, A. L. M.
10.1101/2024.08.09.607029 — cancer biology — Posted on 2024-08-10
3386 Somatic mutation phasing and haplotype extension using linked-reads in multiple myeloma
Foltz, S. M.; Li, Y.; Yao, L.; Terekhanova, N. V.; Weerasinghe, A.; Gao, Q.; Dong, G.; Schindler, M.; Cao, S.; Sun, H.; Jayasinghe, R. G.; Fulton, R. S.; Fronick, C. C.; King, J.; Kohnen, D. R.; Fiala, M. A.; Chen, K.; DiPersio, J. F.; Vij, R.; Ding, L.
10.1101/2024.08.09.607342 — bioinformatics — Posted on 2024-08-10
3387 Novel Insights into Post-Myocardial Infarction Cardiac Remodeling through Algorithmic Detection of Cell-Type Composition Shifts
Gural, B.; Kirkland, L.; Hockett, A.; Sandroni, P.; Zhang, J.; Rosa-Garrido, M.; Swift, S. K.; Chapski, D.; Flinn, M. A.; O'Meara, C. C.; Vondriska, T. M.; Patterson, M.; Jensen, B. C.; Rau, C.
10.1101/2024.08.09.607400 — bioinformatics — Posted on 2024-08-10
3392 Impacts of Cell Ranger versions on Chromium gene expression data
Abugessaisa, I.; Hasegawa, A.; Walker, S.; Katayama, S.; Kere, J.; Kasukawa, T.
10.1101/2024.08.10.607413 — bioinformatics — Posted on 2024-08-10
3393 Fine-tuning of conditional Transformers for the generation of functionally characterized enzymes
Nicolini, M.; Saitto, E.; Jimenez Franco, R. E.; Cavalleri, E.; Mesiti, M.; Galeano Alfonso, A. J.; Malchiodi, D.; Paccanaro, A.; Robinson, P. N.; Casiraghi, E.; Valentini, G.
10.1101/2024.08.10.607430 — bioinformatics — Posted on 2024-08-10
3395 Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs
Rinaldi, C.; Garcia Guerra, A.; Sathyaprakash, C.; de Jong, O. G.; Lim, W.; Vader, P.; Bath, J.; Aoki, Y.; Turberfield, A.; Wood, M.; EL Andaloussi, S.
10.1101/2024.08.09.605335 — bioengineering — Posted on 2024-08-10
3396 Imaging-Guided Metabolic Radiosensitization of Pediatric Rhabdoid Tumors
Xia, W.; Goff, M.; Singh, N.; Huang, J.; Gillespie, D.; Need, E.; Jensen, R.; Pagel, M.; Maity, A.; Shi, S.; Goel, S.
10.1101/2024.08.09.607364 — bioengineering — Posted on 2024-08-10
3397 An asymmetric nautilus-like HflK/C assembly controls FtsH proteolysis of membrane proteins
Ghanbarpour, A.; Telusma, B.; Powell, B. M.; Zhang, J. J.; Bolstad, I.; Vargas, C.; Keller, S.; Baker, T. A.; Sauer, R. T.; Davis, J. H.
10.1101/2024.08.09.604662 — biochemistry — Posted on 2024-08-10
3398 Genesis and regulation of C-terminal cyclic imides from protein damage
Xu, W.; Zhao, Z.; Su, M.; Jain, A.; Lloyd, H. C.; Feng, E. Y.; Cox, N.; Woo, C. M.
10.1101/2024.08.09.606997 — biochemistry — Posted on 2024-08-10
3400 Universal dynamics of cohesin-mediated loop extrusion
Sabate, T.; Lelandais, B.; Robert, M.-C.; Szalay, M.; Tinevez, J.-Y.; Bertrand, E.; Zimmer, C.
10.1101/2024.08.09.605990 — genetics — Posted on 2024-08-10
3402 Human genetic ancestry, Mycobacterium tuberculosis diversity and tuberculosis disease severity in Dar es Salaam, Tanzania
Zwyer, M.; Xu, Z. M.; Ross, A.; Hella, J.; Sasamalo, M.; Rotival, M.; Hiza, H.; Rutaihwa, L. K.; Reither, K.; Fellay, J.; Portevin, D.; Quintana-Murci, L.; Gagneux, S.; Brites, D.
10.1101/2024.08.10.607244 — evolutionary biology — Posted on 2024-08-10
3403 Drosophila melanogaster pigmentation demonstrates adaptive phenotypic parallelism but genomic unpredictability over multiple timescales
Berardi, S.; Rhodes, J. A.; Berner, M. C.; Greenblum, S. I.; Bitter, M. C.; Behrman, E. L.; Betancourt, N. J.; Bergland, A. O.; Petrov, D. A.; Rajpurohit, S.; Schmidt, P.
10.1101/2024.08.09.607378 — evolutionary biology — Posted on 2024-08-10
3405 Environment, plant genetics, and their interaction shape important aspects of sunflower rhizosphere microbial communities
Bueno de Mesquita, C. P.; Walsh, C. M.; Attia, Z.; Koehler, B. D.; Tarble, Z. J.; Van Tassel, D. L.; Kane, N. C.; Hulke, B. S.
10.1101/2024.08.09.607089 — ecology — Posted on 2024-08-10
3406 Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing
Amuso, V.; Haas, M.; Cooper, P.; Chatterjee, R.; Hafiz, S.; Salameh, S.; Gohel, C.; Mazumder, M.; Josephson, V.; Khorsandi, K.; Horvath, A.; Rahnavard, A.; Shook, B.
10.1101/2024.08.09.607357 — cell biology — Posted on 2024-08-10
3407 Identification of Meibomian gland stem cell populations and mechanisms of aging
Zhu, X.; Xu, M.; Portal, C.; Lin, Y.; Ferdinand, A.; Peng, T.; Morrisey, E. E.; Dlugosz, A. A.; Castellano, J. M.; Lee, V.; Seykora, J. T.; Iomini, C.; Millar, S. E.
10.1101/2024.08.09.607015 — cell biology — Posted on 2024-08-10
3408 TUG protein acts through a disordered region to organize the early secretory pathway
Parchure, A.; Tejada, H.; Xi, Z.; Su, M.; Julca-Zevallos, O.; Alcazar-Roman, A. R.; Yan, Y.; Liu, X.; Toomre, D.; Bogan, J. S.
10.1101/2024.08.09.607373 — cell biology — Posted on 2024-08-10
3409 Role of U11/U12 minor spliceosome gene ZCRB1 in Ciliogenesis and WNT Signaling
Powell-Rodgers, G.; Ur Rehman Pirzada, M.; Richee, J.; Jungers, C. F.; Colijn, S.; Stratman, A. N.; Djuranovic, S.
10.1101/2024.08.09.607392 — cell biology — Posted on 2024-08-10
3412 Assessing Autophagy Flux in Glioblastoma Temozolomide Resistant Cells
Clark, C.; Barzegar-Behrooz, A.; Cordani, M.; Shojaei, S.; Ghavami, S.
10.1101/2024.08.09.607348 — molecular biology — Posted on 2024-08-10
3415 Description of the structural and functional genomic composition of L. santarosai serovar Alice
Villarreal-Julio, R. G.; Manjarrez Montes, V. I.; Ordonez Perez, B. E.; Yepes-Blandon, J. A.
10.1101/2024.08.10.607426 — microbiology — Posted on 2024-08-10
3416 Spatial localization of CD16a at the human NK cell ADCC lytic synapse
Ross, P.; Fatima, H.; Leaman, D. P.; Matthias, J.; Spencer, K.; Zwick, M. B.; Henderson, S. C.; Mace, E. M.; Murin, C. D.
10.1101/2024.08.09.605851 — immunology — Posted on 2024-08-10
3417 Sleep defined by arousal threshold reveals decreases in corticocortical functional correlations independently from the conventional sleep stages
Picchioni, D.; Yang, F. N.; de Zwart, J. A.; Mandelkow, H.; Ozbay, P. S.; Chen, G.; Taylor, P. A.; Lam, N.; Chappel-Farley, M. G.; Chang, C.; Liu, J.; van Gelderen, P.; Duyn, J. H.
10.1101/2024.08.09.607376 — neuroscience — Posted on 2024-08-10
3418 Chickpea NCR13 disulfide cross-linking variants exhibit profound differences in antifungal activity and modes of action
Godwin, J.; Djami-Tchatchou, A. T.; Velivelli, S. L. S.; Tetorya, M.; Kalunke, R.; Pokhrel, A.; Zhou, M.; Buchko, G. W.; Czymmek, K.; Shah, D.
10.1101/2024.08.09.607347 — plant biology — Posted on 2024-08-10
3419 microRNA-1 Regulates Metabolic Flexibility in Skeletal Muscle via Pyruvate Metabolism
Ismaeel, A.; Peck, B. D.; Montgomery, M. M.; Burke, B. I.; Goh, J.; Kang, G.; Franco, A. B.; Xia, Q.; Goljanek-Whysall, K.; McDonagh, B.; McLendon, J. M.; Koopmans, P. J.; Jacko, D.; Schaaf, K.; Bloch, W.; Gehlert, S.; Wen, Y.; Murach, K. A.; Peterson, C. A.; Boudreau, R. L.; Fisher-Wellman, K. H.; McCarthy, J. J.
10.1101/2024.08.09.607377 — physiology — Posted on 2024-08-10
3421 dia-PASEF Proteomics of Tumor and Stroma LMD Enriched from Archived HNSCC Samples
Panigrahi, A.; Hunt, A. L.; Assis, D.; Willetts, M.; Kallakury, B. V.; Davidson, B.; Conrads, T. P.; Goldman, R.
10.1101/2024.08.09.607341 — cancer biology — Posted on 2024-08-10
3422 TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma
Li, J.; Huang, K.; McBride, F.; Sadagopan, A.; Gallant, D. S.; Thakur, M.; Khanna, P.; Li, B.; Ge, M.; Weiss, C. N.; Achom, M.; Xu, Q.; Huang, K.; Ryback, B. A.; Gui, M.; bar-peled, l.; Viswanathan, S. R.
10.1101/2024.08.09.607311 — cancer biology — Posted on 2024-08-10
3426 Drug Repurposing using Consilience of Knowledge Graph Completion Methods
Tu, R.; Sinha, M.; Gonzalez-Cavazos, A. C.; Hu, E.; Dhuliawala, S. Z.; McCallum, A.; Su, A. I.
10.1101/2023.05.12.540594 — bioinformatics — Posted on 2024-08-10
3427 Path-based reasoning in biomedical knowledge graphs with BioPathNet
Hu, Y.; Oleshko, S.; Firmani, S.; Zhu, Z.; Cheng, H.; Ulmer, M.; Arnold, M.; Colome-Tatche, M.; Tang, J.; Xhonneux, S.; Marsico, A.
10.1101/2024.06.17.599219 — bioinformatics — Posted on 2024-08-10
3428 Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models
Zhang, Y.; Savvidou, M.; Liaudanskaya, V.; Ramanathan, V.; Bui, T.; Matthew, L.; Sze, A.; Ugwu, U. O.; Yuhang, F.; Matthew, D. E.; Chen, X.; Nasritdinova, S.; Dey, A.; Miller, E. L.; Kaplan, D. L.; Georgakoudi, I.
10.1101/2024.08.08.607216 — bioengineering — Posted on 2024-08-10
3429 Rapid turnover of centromeric DNA reveals signatures of genetic conflict in Drosophila
Courret, C.; Hemmer, L.; Wei, X.; Patel, P. D.; Santinello, B.; Fuda, N. J.; Geng, X.; Chang, C.-H.; Mellone, B.; Larracuente, A. M.
10.1101/2023.08.22.554357 — evolutionary biology — Posted on 2024-08-10
3431 Cross-transmission of resistant gastrointestinal nematodes between wildlife and transhumant sheep
Beaumelle, C.; Toigo, C.; Papet, R.; Benabed, S.; Beurier, M.; Bordes, L.; Brignone, A.; Curt-Grand-Gaudin, N.; Garel, M.; Ginot, J.; Jacquiet, P.; Miquel, C.; Poirel, M.-T.; Serafino, A.; Vannard, E.; Bourgoin, G.; Yannic, G.
10.1101/2023.07.21.550073 — ecology — Posted on 2024-08-10
3432 Dissecting infant leukemia developmental origins with a hemogenic gastruloid model
Ragusa, D.; Suen, C. W.; Torregrosa Cortes, G.; Pastorino, F.; Johns, A.; Ciciro, Y.; Dijkhuis, L.; van den Brink, S.; Cilli, M.; Byrne, C.; Ionescu, G.-A.; Cerveira, J.; Kranc, K. R.; Hernandez-Hernandez, V.; Ponzoni, M.; Bigas, A.; Garcia-Ojalvo, J.; Martinez Arias, A.; Pina, C.
10.1101/2022.10.07.511362 — developmental biology — Posted on 2024-08-10
3434 OCTOPUS: Disk-based, Multiplatform, Mobile-friendly Metagenomics Classifier
Marini, S.; Barquero, A.; Wadhwani, A. A.; Bian, J.; Ruiz, J.; Boucher, C.; Prosperi, M.
10.1101/2024.03.15.585215 — molecular biology — Posted on 2024-08-10
3435 MAPK13 controls structural remodeling and disease after epithelial injury
Wu, K.; Zhang, Y.; Mao, D.; Iberg, C. A.; Yin-Declue, H.; Sun, K.; Keeler, S. P.; Wikfors, H. A.; Young, D.; Yantis, J.; Austin, S. R.; Byers, D. E.; Brody, S. L.; Crouch, E. C.; Holtzman, M. J.
10.1101/2024.05.31.596863 — immunology — Posted on 2024-08-10
3436 MAC3A and MAC3B modulate FLM splicing to repress photoperiod-dependent floral transition
Huang, Y.-W.; Tseng, C.-Y.; Tu, Y.-T.; Hsieh, H.-Y.; Wang, Y.-S.; Chen, Y.-Z.; Ly, Y.-T.; Tu, S.-L.; Lee, C.-M.
10.1101/2024.03.26.586198 — plant biology — Posted on 2024-08-10
3438 Assessment of Antimicrobial Therapy in Eradicating Chlamydia muridarum in Research Mice: Immune Status and its Impact on Outcomes
Palillo, M. B.; Carrasco, S.; Mishkin, N.; Palillo, J. A.; Lynch, D. B.; Lawton, S. K.; Aydin, M.; Mourino, A.; Lipman, N.; Ricart Arbona, R.
10.1101/2024.06.28.600682 — pharmacology and toxicology — Posted on 2024-08-10
3440 Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C1-related protein
Nel, L.; Thaysen, K.; Jamecna, D.; Olesen, E.; Szomek, M.; Langer, J.; Frain, K. M.; Hoeglinger, D.; Wustner, D.; Pedersen, B. P.
10.1101/2024.06.10.598172 — biophysics — Posted on 2024-08-10
3441 Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting
Wu, Y.; Yan, Y.; Yang, Y.; Bian, S.; Rivetta, A.; Allen, K.; Sigworth, F. J.
10.1101/2023.06.02.543446 — biophysics — Posted on 2024-08-10
3443 Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression
Dominguez Mantes, A.; Herrera, A.; Khven, I.; Schlaeppi, A.; Kyriacou, E.; Tsissios, G.; Skoufa, E.; Santangeli, L.; Buglakova, E.; Durmus, E. B.; Manley, S.; Kreshuk, A.; Arendt, D.; Aztekin, C.; Ligner, J.; La Manno, G.; Weigert, M.
10.1101/2024.02.01.578426 — bioinformatics — Posted on 2024-08-10
3448 Mechanistic origin and preimplantation development of uniparental and polyploid blastomeres
Zhao, Y.; Fernandez-Montoro, A.; Peeters, G.; Jatsenko, T.; De Coster, T.; Angel-Velez, D.; Lefevre, T.; Voet, T.; Tsuiko, O.; Kurg, A.; Smits, K.; Van Soom, A.; Vermeesch, J. R.
10.1101/2024.07.30.605883 — genetics — Posted on 2024-08-10
3451 A punctuated burst of massive genomic rearrangements and the origin of non-marine annelids
Vargas-Chavez, C.; Benitez-Alvarez, L.; Martinez-Redondo, G. I.; Alvarez-Gonzalez, L.; Salces-Ortiz, J.; Eleftheriadi, K.; Escudero, N.; Guiglielmoni, N.; Flot, J.-F.; Novo, M.; Ruiz-Herrera, A.; McLysaght, A.; Fernandez, R.
10.1101/2024.05.16.594344 — evolutionary biology — Posted on 2024-08-10
3454 RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress
Mohanan, G.; Roy, R.; Malka-Mahieu, H.; Lamba, S.; Fabbri, L.; Biswas, A.; Martineau, S.; Labbe, C.; Vagner, S.; Rajyaguru, P. I.
10.1101/2022.07.12.499753 — cell biology — Posted on 2024-08-10
3456 Examining the relationship between psychosocial adversity and inhibitory control: an fMRI study of children growing up in extreme poverty
Surani, Z.; Turesky, T. K.; Sullivan, E.; Shama, T.; Haque, R.; Islam, N.; Kakon, S. H.; Yu, X.; Petri, W. A.; Nelson, C.; Gaab, N.
10.1101/2024.02.05.578942 — neuroscience — Posted on 2024-08-10
3460 Multimodal system for recording individual-level behaviors in songbird groups
Rüttimann, L.; Wang, Y.; Rychen, J.; Tomka, T.; Hörster, H.; Rocha, M. D.; Hahnloser, R. H.
10.1101/2022.09.23.509166 — animal behavior and cognition — Posted on 2024-08-10
3461 Causal inference for multiple risk factors and diseases from genomics data
Machnik, N.; Mahmoudi, M.; Borczyk, M.; Kraetschmer, I.; Bauer, M. J.; Robinson, M. R.
10.1101/2023.12.06.570392 — genetics — Posted on 2024-08-10
3462 Regional patterns of human cortex development correlate with underlying neurobiology
Lotter, L. D.; Saberi, A.; Hansen, J. Y.; Misic, B.; Paquola, C.; Barker, G. J.; Bokde, A. L. W.; Desrivieres, S.; Flor, H.; Grigis, A.; Garavan, H.; Gowland, P.; Heinz, A.; Bruehl, R.; Martinot, J.-L.; Paillere, M.-L.; Artiges, E.; Papadopoulos Orfanos, D.; Paus, T.; Poustka, L.; Hohmann, S.; Froehner, J. H.; Smolka, M. N.; Vaidya, N.; Walter, H.; Whelan, R.; Schumann, G.; IMAGEN Consortium, ; Nees, F.; Banaschewski, T.; Eickhoff, S. B.; Dukart, J.
10.1101/2023.05.05.539537 — neuroscience — Posted on 2024-08-10
3463 Criterion placement threatens the construct validity of neural measures of consciousness
Fahrenfort, J. J.; Johnson, P. A.; Kloosterman, N. A.; Stein, T.; van Gaal, S.
10.1101/2024.02.22.581517 — neuroscience — Posted on 2024-08-10
3466 The Phylogeny and the Evolution of Parasitic Strategies in Trematoda
Chuanyu, X.; Jakovlic, I.; Ye, T.; Song, R.; Zou, H.; Wang, G.; Li, W.; Zhang, D.
10.1101/2024.08.09.607286 — evolutionary biology — Posted on 2024-08-09
3468 Nanobody immunolabelling and three-dimensional imaging reveals spatially restricted LYVE1 expression by kidney lymphatic vessels in mice
Funk, E. M.; Jafree, D.; Hansmeier, N. R.; Abad Baucells, C.; Behncke, R. Y.; Pomeranz, G.; Kolatsi-Joannou, M.; Mason, W.; Moulding, D.; Russell, L. G.; Ulferts, S.; Wilson, L.; Long, D.; Haegerling, R.
10.1101/2024.08.09.607309 — immunology — Posted on 2024-08-09
3469 Making the effect visible - OX40 targeting nanobodies for in vivo imaging of activated T cells
Frecot, D. I.; Blaess, S.; Wagner, T. R.; Kaiser, P. D.; Traenkle, B.; Fandrich, M.; Jakobi, M.; Scholz, A. M.; Nueske, S.; Schneiderhan-Marra, N.; Gouttefangeas, C.; Kneilling, M.; Pichler, B. J.; Sonanini, D.; Rothbauer, U.
10.1101/2024.08.09.607337 — immunology — Posted on 2024-08-09
3470 Overexpression of the Apoe gene in the frontal cortex of mice causes sex-dependent changes in learning, attention, and anxiety-like behavior
Ramos, L.; Harr, A. E.; Zakas, F. L.; Essig, S. R.; Kempskie, G. J.; Fadil, N. A.; Schmid, M. G.; Pompy, M. D.; Curley, M. C.; Gabel, L. A.; Hallock, H. L.
10.1101/2024.08.08.607225 — neuroscience — Posted on 2024-08-09
3471 Do transformers and CNNs learn different concepts of brain age?
Siegel, N. T.; Kainmueller, D.; Deniz, F.; Ritter, K.; Schulz, M.-A.
10.1101/2024.08.09.607321 — neuroscience — Posted on 2024-08-09
3473 Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis
Ruiz, A.; Benucci, S.; Meier, H.; Schultz, G.; Buczak, K.; Handschin, C.; Pena, R. C. G.; Treves, S.; Zorzato, F.
10.1101/2024.08.09.607317 — physiology — Posted on 2024-08-09
3475 Interactions between neutrophils and macrophages harboring gram-negative bacteria promote obesity-associated breast cancer
Takle, S. T.; Grondal, S. M.; Lien, M. E.; Lianto, P.; Deng, W.; Lillestol, R. K.; Lonning, P.; Lorens, J. B.; Knappskog, S.; Halberg, N.
10.1101/2024.08.08.607253 — cancer biology — Posted on 2024-08-09
3476 EVE is an open modular data analysis software for event-based localization microscopy
Weber, L. M.; Martens, K. J. A.; Cabriel, C.; Gates, J. J.; Albecq, M.; Vermeulen, F.; Hein, K.; Izeddin, I.; Endesfelder, U.
10.1101/2024.08.09.607224 — biophysics — Posted on 2024-08-09
3477 Intra-cluster receptor density (IRD) dictates TNFR1 clusters' signaling efficacy
Jana, S.; Roy, P.; Das, J.; Biswas, P.; Nanda, N.; Sinha, B.; Sinha, D.
10.1101/2024.08.09.607302 — biophysics — Posted on 2024-08-09
3481 In-silico identification of archaeal DNA-binding proteins
Donvil, L.; Housmans, J. A. J.; Peeters, E.; Vranken, W. F.; Orlando, G.
10.1101/2024.08.09.607351 — bioinformatics — Posted on 2024-08-09
3483 The Rad52 superfamily as seen by AlphaFold
Al-Fatlawi, A.; Hossen, M. B.; de Paula Lopes, S.; Stewart, A. F.; Schroeder, M.
10.1101/2024.08.09.607149 — bioinformatics — Posted on 2024-08-09
3486 Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models
Zhang, Y.; Savvidou, M.; Liaudanskaya, V.; Ramanathan, V.; Bui, T.; Matthew, L.; Sze, A.; Ugwu, U. O.; Yuhang, F.; Matthew, D. E.; Chen, X.; Nasritdinova, S.; Dey, A.; Miller, E. L.; Kaplan, D. L.; Georgakoudi, I.
10.1101/2024.08.08.607216 — bioengineering — Posted on 2024-08-09
3487 Sexual Dimorphism in Jump Kinematics and Choreography in Peacock Spiders
Narendra, A.; Seibel, A.; Ramirez-Esquivel, F.; Joshi, P.; McLean, D. J.; Robledo-Ospina, L.; Rao, D.
10.1101/2024.08.09.607331 — animal behavior and cognition — Posted on 2024-08-09
3488 Phosphate transporter (Pht) gene families in rye (Secale cereale L.) - genome-wide identification and sequence diversity assessment
Chan-Rodriguez, D.; Koboyi, B. W.; Werghi, S.; Till, B. J.; Maksymiuk, J.; Shoormij, F.; Hilderlith, A.; Hawliczek, A.; Krolik, M.; Bolibok-Bragoszewska, H.
10.1101/2024.08.09.607312 — genomics — Posted on 2024-08-09
3489 Integrating gene expression and imaging data across Visium capture areas with visiumStitched
Eagles, N. J.; Bach, S. V.; Tippani, M.; Ravichandran, P.; Du, Y.; Miller, R. A.; Hyde, T.; Page, S. C.; Martinowich, K.; Collado-Torres, L.
10.1101/2024.08.08.607222 — genomics — Posted on 2024-08-09
3494 Rapid GIT transit time in volant vertebrates, with implications for convergence in microbiome composition
Cornelius Ruhs, E.; McFerrin, K.; Jones, D. N.; Cortes-Delgado, N.; Ravelomanantsoa, N. A. F.; Yeoman, C. J.; Plowright, R. K.; Brook, C. E.
10.1101/2024.08.09.607319 — ecology — Posted on 2024-08-09
3500 Hypoxia promotes airway differentiation in the human lung epithelium
Dong, Z.; Wit, N.; Agarwal, A.; Dubal, D.; van den Ameele, J.; Reid, A. J.; Nathan, J. A.; Rawlins, E.
10.1101/2024.08.09.607336 — developmental biology — Posted on 2024-08-09
3502 JMJD3 mediated senescence is required to overcome stress induced hematopoietic defects.
Nakata, Y.; Ueda, T.; Sera, Y.; Kanai, A.; Ikeda, K.-i.; Yamasaki, N.; Nagamachi, A.; Kobatake, K.; Taguchi, M.; Sotomaru, Y.; Ichinohe, T.; Honda, Z.-i.; Manabe, I.; Suda, T.; Takubo, K.; Kaminuma, O.; Honda, H.
10.1101/2024.08.08.607138 — cell biology — Posted on 2024-08-09
3504 Cryo-EM structure and evolutionary history of the conjugation surface exclusion protein TraT
Seddon, C.; David, S.; Wong, J. L. C.; Ishimoto, N.; Bradshaw, J.; He, S.; Low, W. W.; Frankel, G.; Beis, K.
10.1101/2024.08.09.607165 — microbiology — Posted on 2024-08-09
3507 Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows
Halwe, N. J.; Cool, K.; Breithaupt, A.; Schoen, J.; Trujillo, J. D.; Nooruzzaman, M.; Kwon, T.; Ahrens, A. K.; Britzke, T.; McDowell, C. D.; Piesche, R.; Singh, G.; Pinho dos Reis, V.; Kafle, S.; Pohlmann, A.; Gaudreault, N. N.; Corleis, B.; Ferreyra, F. M.; Carossino, M.; Balasuriya, U. B. R.; Hensley, L.; Morozov, I.; Covaleda, L. M.; Diel, D.; Ulrich, L.; Hoffmann, D.; Beer, M.; Richt, J. A.
10.1101/2024.08.09.607272 — microbiology — Posted on 2024-08-09
3508 Genetically and Functionally Distinct Immunoglobulin Heavy Chain Locus Duplication in Bats
Pursell, T.; Reers, A.; Mikelov, A.; Kotagiri, P.; Ellison, J. A.; Hutson, C. L.; Boyd, S. D.; Frank, H. K.
10.1101/2024.08.09.606892 — immunology — Posted on 2024-08-09
3509 Efficacy of a new multivalent vaccine for the control of bovine respiratory disease (BRD) in commercial fattening units
Tapiolas, M.; Gibert, M.; Montbrau, C.; Taberner, E.; Sole, M.; Santo Tomas, H.; Puig, A.; March, R.
10.1101/2024.08.07.606972 — immunology — Posted on 2024-08-09
3517 Geometric eigenmode brain fingerprinting and its longitudinal associations with adolescent mental health and wellbeing
Boyes, A.; Schwenn, P. E.; Shan, Z.; Korgaonkar, M. S.; Pang, J. C.; Prince, T.; Mills, L.; Kennedy, M. F.; Hermens, D. F.
10.1101/2024.08.08.607260 — neuroscience — Posted on 2024-08-09
3518 Seed-competent alpha-synuclein pathology in metachromatic leukodystrophy: the expanding spectrum of alpha-synucleinopathy in sphingolipidoses
Ghanem, S.; Hawksworth, J.; Thom, S.; Hartanto, A. E.; O'Neill, J.; Ponraj, J.; Mansour, S.; Attems, J.; Pyle, A.; Johnson, L.; Baines, J.; Taylor, R. W.; Outeiro, T. F.; El-Agnaf, O.; Erskine, D.
10.1101/2024.08.09.607301 — neuroscience — Posted on 2024-08-09
3520 Pharmacogenomic screening identifies and repurposes leucovorin and dyclonine as pro-oligodendrogenic compounds in brain repair
Hure, J.-B.; Foucault, L.; Ghayad, L.-M.; Marie, C.; Vachoud, N.; Baudouin, L.; Azmani, R.; Ivjanin, N.; Arevalo-Nuevo, A.; Pigache, M.; Bouslama-Oueghlani, L.; Chemelle, J.-A.; Dronne, M.-A.; Terreux, R.; Hassan, B.; Gueyffier, F.; Raineteau, O.; Parras, C.
10.1101/2024.08.08.607135 — neuroscience — Posted on 2024-08-09
3521 Alterations of the skeletal muscle nuclear proteome after acute exercise reveals a post-transcriptional influence.
Martin, R. A.; Viggars, M. R.; Sanford, J. A.; Taylor, Z. W.; Hansen, J. R.; Clair, G. C.; Adkins, J. N.; Douglas, C. M.; Esser, K. A.
10.1101/2024.08.08.607176 — physiology — Posted on 2024-08-09
3523 Caution when using network partners for target identification in drug discovery
Tan, D.; Chen, Y.; Ilboudo, Y.; Liang, K. Y. H.; Butler-Laporte, G.; Richards, J. B.
10.1101/2024.08.08.607024 — pharmacology and toxicology — Posted on 2024-08-09
3526 CarpeDeam: A De Novo Metagenome Assemblerfor Heavily Damaged Ancient Datasets
Kraft, L.; Soeding, J.; Steinegger, M.; Jochheim, A.; Fernandez-Guerra, A.; Renaud, G.
10.1101/2024.08.09.607291 — genomics — Posted on 2024-08-09
3529 Drosophila ring chromosomes interact with sisters and homologs to produceanaphase bridges in mitosis.
Lin, H.-C.; Golic, M. M.; Hill, H. J.; Lemons, K. F.; Vuong, T. T.; Smith, M.; Golic, F. T.; Golic, K. G.
10.1101/2024.08.08.607186 — genetics — Posted on 2024-08-09
3530 A newly evolved gene is essential for efficient sperm entry into eggs in Drosophila melanogaster
Guay, S. Y.; Patel, P. H.; Thomalla, J. M.; McDermott, K. L.; O'Toole, J. M.; Arnold, S. E.; Obrycki, S. J.; Wolfner, M. F.; Findlay, G. D.
10.1101/2024.08.08.607187 — genetics — Posted on 2024-08-09
3532 Complex genetic determination of male-fertility restoration in the gynodioecious snail Physa acuta
Skarlou, E.; Laugier, F.; Bethune, K.; Chenin, T.; Donnay, J.-M.; Froissard, C.; David, P.
10.1101/2024.08.08.607164 — evolutionary biology — Posted on 2024-08-09
3535 Tracing Endometriosis: Coupling deeply phenotyped, single-cell based Endometrial Differences and AI for disease pathology and prediction
Duempelmann, L.; Sheppard, S.; Duo, A.; Skrabalova, J.; McKinnon, B.; Andrieu, T.; Goehlsdorf, D.; Muzumdar, S.; Donato, C.; Lusby, R.; Solass, W.; Bosmuller, H.; Nestorov, P.; Mueller, M.
10.1101/2024.08.09.606959 — molecular biology — Posted on 2024-08-09
3536 Hydrocarbon Metabolism and Petroleum Seepage as Ecological and Evolutionary Drivers for Cycloclasticus
Arrington, E. C.; Tarn, J.; Kivenson, V.; Nunn, B. L.; Liu, R. M.; Paul, B. G.; Valentine, D. L.
10.1101/2024.08.08.607087 — microbiology — Posted on 2024-08-09
3538 New tools to monitor Pseudomonas aeruginosa infection and biofilms in vivo in C. elegans.
Ezcurra, M.; Ragno, M.; Xue, F.; Blackburn, S. A.; Fasseas, M.; Maitra, S.; Tholozan, F.; Thompson, R.; Sellars, L.; Hall, R.; Saunter, C.; Weinkove, D.
10.1101/2024.08.09.607303 — microbiology — Posted on 2024-08-09
3541 The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2
Suryawanshi, R. K.; Jaishankar, P.; Correy, G. J.; Rachman, M. M.; O'Leary, P. C.; Taha, T. Y.; Zapatero-Belinchon, F. J.; McCavitt-Malvido, M.; Doruk, Y. U.; Stevens, M. G. V.; Diolati, M. E.; Jogalekar, M. P.; Richards, A. L.; Montano, M.; Rosecrans, J.; Matthay, M.; Togo, T.; Gonciarz, R. L.; Gopalkrishnan, S.; Neitz, R. J.; Krogan, N. J.; Swaney, D. L.; Shoichet, B. K.; Ott, M.; Renslo, A. R.; Ashworth, A.; Fraser, J. S.
10.1101/2024.08.08.606661 — immunology — Posted on 2024-08-09
3544 DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy
Lofiego, M. F.; Tufano, R.; Bello, E.; Solmonese, L.; Marzani, F.; Piazzini, F.; Celesti, F.; Caruso, F. P.; Noviello, T. M. R.; Mortarini, R.; Anichini, A.; Ceccarelli, M.; Calabro', L.; Maio, M.; Coral, S.; Di Giacomo, A. M.; Covre, A.
10.1101/2024.08.08.607174 — cancer biology — Posted on 2024-08-09
3546 DeepKin: Predicting relatedness from low-coverage genomes and paleogenomes with convolutional neural networks
Guler, M. N.; Yilmaz, A.; Katircioglu, B.; Kantar, S.; Unver, T. E.; Vural, K. B.; Altinisik, N. E.; Akbas, E.; Somel, M.
10.1101/2024.08.08.607159 — bioinformatics — Posted on 2024-08-09
3552 Systemic metabolic changes in acute and chronic lymphocytic choriomeningitis virus infection
Bartman, C. R.; Hou, S.; Correa, F.; Shen, Y.; da Silva-Diz, V.; Aleksandrova, M.; Herranz, D.; Rabinowitz, J.; Intlekofer, A. M.
10.1101/2024.08.09.607318 — immunology — Posted on 2024-08-09
3554 Iso-Seq enables discovery of novel isoform variants in human retina at single cell resolution
Wang, L.; Urrutia-Cabrera, D.; Hung, S. S.-C.; Hewitt, A. W.; Lukowski, S. W.; Foord, C.; Wang, P.-Y.; Tilgner, H.; Wong, R.
10.1101/2024.08.08.607267 — genomics — Posted on 2024-08-09
3556 Biogenesis, engineering and function of membranes in the CO2-fixing pyrenoid
Hennacy, J. H.; Atkinson, N.; Kayser-Browne, A.; Ergun, S. L.; Franklin, E.; Wang, L.; Kafri, M.; Fauser, F.; Vilarrasa-Blasi, J.; Jinkerson, R. E.; McCormick, A. J.; Jonikas, M. C.
10.1101/2024.08.08.603944 — molecular biology — Posted on 2024-08-09
3557 Neurofibromin deficiency alters the patterning and prioritization of motor behaviors in a state-dependent manner
Suarez, G. O.; Kumar, D. S.; Brunner, H.; Emel, J. A.; Teel, J.; Knauss, A.; Botero, V.; Broyles, C. N.; Stahl, A.; Bidaye, S. S.; Tomchik, S. M.
10.1101/2024.08.08.607070 — neuroscience — Posted on 2024-08-09
3558 Aperiodic neural activity distinguishes between phasic and tonic REM sleep
Rosenblum, Y.; Bogdany, T.; Nadasy, L. B.; Kovacs, I.; Gombos, F.; Ujma, P.; Bodizs, R.; Adelhöfer, N.; Simor, P.; Dresler, M.
10.1101/2024.08.08.606670 — neuroscience — Posted on 2024-08-09
3559 The force-sensing GPCR LPHN2 is indispensable for normal auditory function
Yang, Z.; Wang, M.-W.; Zhou, S.-H.; Song, Z.-c.; Zhu, K.-K.; Wen, X.; Zhang, Q.-Y.; Guan, Y.; Gao, J.-R.; Wang, X.-H.; Wang, Y.-Q.; Liu, W.-W.; Xu, L.; Xiong, W.; Chai, R.; Wang, C.; Xu, Z.-G.; Yu, X.; Sun, J.-P.
10.1101/2023.10.24.563883 — physiology — Posted on 2024-08-09
3560 Dissecting the metabolic costs of up- and down-hill walking
Jessup, L. N.; Kelly, L. A.; Cresswell, A. G.; Lichtwark, G. A.
10.1101/2024.08.08.607266 — physiology — Posted on 2024-08-09
3561 A force-sensitive adhesion GPCR is indispensable in normal equilibrioception
Yang, Z.; Zhou, S.; Zhang, Q.; Song, Z.; Liu, W.; Sun, Y.; Wang, M.; Fu, X.; Zhu, K.; Guan, Y.; Qi, J.; Wang, X.; Sun, Y.; Lu, Y.; Ping, Y.; Xi, Y.; Xu, Z.; Xiong, W.; Qin, W.; Yang, W.; Yi, F.; Yu, X.; Chai, R.; Sun, J.
10.1101/2023.10.24.563886 — physiology — Posted on 2024-08-09
3564 Computational Prediction of Multiple Antigen Epitopes
Viswanathan, R.; Carroll, M.; Roffe, A.; Fajardo, J. E.; Fiser, A.
10.1101/2024.08.08.607232 — bioinformatics — Posted on 2024-08-09
3565 Sequencing of historical plastid genomes reveal exceptional genetic diversity in early domesticated rye plants
Komluski, J.; Filatova, S.; Schlütz, F.; Claassen, B.; Roesch, M.; Krause-Kyora, B.; Kirleis, W.; Stukenbrock, E.
10.1101/2024.08.08.607158 — evolutionary biology — Posted on 2024-08-09
3570 Centrocortin potentiates co-translational localization of its mRNA to the centrosome via dynein
Zein-Sabatto, H.; Brockett, J. S.; Jin, L.; Husbands, C.; Lee, J.; Fang, J.; Buehler, J.; Bullock, S. L.; Lerit, D. A.
10.1101/2024.08.09.607365 — cell biology — Posted on 2024-08-09
3571 Adaptive immunity to retroelements promotes barrier integrity
Wells, A. C.; Lima-Junior, D. S.; Link, V. M.; Smelkinson, M.; Krishnamurthy, S. R.; Chi, L.; Segrist, E.; Rivera, C. A.; Teijeiro, A.; Bouladoux, N.; Belkaid, Y.
10.1101/2024.08.09.606346 — immunology — Posted on 2024-08-09
3572 Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Identities from Microglia
Du, S.; Drieu, A.; Cheng, Y.; Storck, S.; Rustenhoven, J.; Mamuladze, T.; Bhattarai, B.; Brioschi, S.; Nguyen, K.; Ou, F.; Cao, J.; Rodrigues, P.; Smirnov, I.; DeNardo, D.; Ginhoux, F.; Cella, M.; Colonna, M.; Kipnis, J.
10.1101/2024.08.08.606900 — immunology — Posted on 2024-08-09
3575 Magnetoencephalography dimensionality reduction informed by dynamic brain states
Cathignol, A. E.; Kusch, L.; Angiolelli, M.; Troisi Lopez, E.; Polverino, A.; Romano, A.; Sorrentino, G.; Jirsa, V.; Rabuffo, G.; Sorrentino, P.
10.1101/2024.08.08.607151 — neuroscience — Posted on 2024-08-09
3577 Local Nearby Bifurcations Lead to Synergies in Critical Slowing Down: the Case of Mushroom Bifurcations
Fucho, M.; Maretvadakethop, S.; Perez-Carrasco, R.; Haro, A.; Alarcon, T.; Sardanyes, J. d. R.
10.1101/2024.08.08.607203 — systems biology — Posted on 2024-08-09
3582 DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in C. elegans amyloid beta proteotoxicity
Peng, W.; Chung, K. B.; Lawrence, B. P.; O'Banion, M. K.; Dirksen, R. T.; Wojtovich, A. P.; Onukwufor, J. O.
10.1101/2024.08.08.607074 — pharmacology and toxicology — Posted on 2024-08-09
3583 Pyruvate from bone marrow mesenchymal stem cells supports myeloma redox homeostasis and anabolism
Vera-Siguenza, E.; Escribano-Gonzalez, C.; Serrano-Gonzalo, I.; Eskla, K.-L.; Speakman, C.; Huerta-Uribe, A.; Vettore, L.; Rana, H.; Boufersaoui, A.; Vellama, H.; Nashiebi, R.; Cloete, I.; Roberts, J.; Basu, S.; Drayson, M.; Bunce, C.; Pratt, G.; Spill, F.; Maddocks, O. D. K.; Tennant, D. A.
10.1101/2024.08.08.607157 — cancer biology — Posted on 2024-08-09
3584 Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity
Weissenrieder, J. S.; Peura, J.; Paudel, U.; Bhalerao, N.; Weinmann, N.; Johnson, C.; Wengyn, M.; Drager, R.; Furth, E. E.; Simin, K.; Ruscetti, M.; Stanger, B.; Rustgi, A. K.; Pitarresi, J. R.; Foskett, J. K.
10.1101/2024.08.08.607195 — cancer biology — Posted on 2024-08-09
3585 Efficient and effective identification of cancer neoantigens from tumor only RNA-seq
Tatoni, D.; Dalsass, M.; Brunelli, G.; Grandi, G.; Chiariello, M.; D'Aurizio, R.
10.1101/2024.08.08.607127 — bioinformatics — Posted on 2024-08-09
3588 Organ Chips with integrated multifunctional sensors enable continuous metabolic monitoring at controlled oxygen levels
Izadifar, Z.; Charrez, B.; Almeida, M.; Robben, S.; Pilobello, K.; van der Graaf-Mas, J.; Benz, M.; Marquez, S. L.; Ferrante, T. C.; Shcherbina, K.; Gould, R.; LoGrande, N. T.; Sesay, A. M.; Ingber, D. E.
10.1101/2024.08.08.606660 — bioengineering — Posted on 2024-08-09
3589 The molecular structure of an axle-less F1-ATPase
Furlong, E. J.; Reininger-Chatzigiannakis, I.-B. P.; Zeng, Y. C.; Brown, S. H. J.; Sobti, M.; Stewart, A. G.
10.1101/2024.08.08.607276 — biochemistry — Posted on 2024-08-09
3590 The Neuroactive Potential of the Elderly Human Gut Microbiome is Associated with Mental Health Status
Calderon Romero, P. F.; Valderrama, B.; Bastiaanssen, T.; Lillo, P.; Thumala, D.; Clarke, G.; Cryan, J. F.; Slachevsky, A.; Gonzalez-Billault, C.; Court, F.
10.1101/2024.08.08.607034 — animal behavior and cognition — Posted on 2024-08-09
3591 Genomic re-sequencing reveals substantial mutational divergence across genetically engineered strains of model archaea
Soborowski, A. L.; Hackley, R. K.; Hwang, S.; Zhou, G.; Dulmage, K. A.; Schonheit, P.; Daniels, C.; Bisson, A.; Marchfelder, A.; Maupin-Furlow, J. A.; Allers, T.; Schmid, A. K.
10.1101/2024.08.08.607208 — genomics — Posted on 2024-08-09
3594 Recent climate change strongly impacted the population dynamic of a North American insect pest species
Boulanger, Y.; Desaint, A.; Martel, V.; Marchand, M.; Massoda Tonye, S.; Saint-Amant, R.; Regniere, J.
10.1101/2024.08.08.607030 — ecology — Posted on 2024-08-09
3595 Tunable Cytosolic Chloride Indicators for Real-Time Chloride Imaging in Live Cells
Morse, J.; Nadiveedhi, M. R.; Schmidt, M.; Tang, F.-K.; Hladun, C.; Ganesh, P.; Qiu, Z.; Leung, K.
10.1101/2024.08.08.606814 — cell biology — Posted on 2024-08-09
3596 SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant tumor cells
Bernhardt, M.; Rech, A.; Berthold, M.; Lappe, M.; Herbel, J.-N.; Erhard, F.; Paschen, A.; Schilling, B.; Schlosser, A.
10.1101/2024.08.08.606999 — immunology — Posted on 2024-08-09
3600 A Draft Pacific Ancestry Pangenome Reference
Littlefield, C. C.; Lazaro-Guevara, J. M.; Stucki, D.; Lansford, M.; Pezzolesi, M. H.; Taylor, E. J.; Wolfgramm, E. M. C.; Taloa, J.; Lao, K.; Dumaguit, C. D.; Ridge, P. G.; Tavana, J. P.; Holland, W. L.; Raphael, K. L.; Pezzolesi, M. G.
10.1101/2024.08.07.606392 — genomics — Posted on 2024-08-09
3603 NKX2.2 and KLF4 cooperate to regulate alpha cell identity
Brooks, E. P.; Casey, M. R.; Wells, K. L.; Liu, T.-Y.; Van Orman, M.; Sussel, L.
10.1101/2024.08.07.607083 — developmental biology — Posted on 2024-08-09
3605 CD131 Contributes to Ulcerative Colitis Pathogenesis by Promoting Macrophage Infiltration
Wu, Z.; Liu, L.; He, C.; Xiao, L.; Yun, D.; Chen, J.; Liu, Z.; Li, W.; Lv, Q.; Tan, X.
10.1101/2024.08.07.606991 — immunology — Posted on 2024-08-09
3607 Disrupted stimulus encoding shapes tactile perception in autism.
Semelidou, O.; Gauvrit, T.; Vandromme, C.; Cornier, A.; Saint-Jean, A.; Le Feuvre, Y.; Ginger, M.; Frick, A.
10.1101/2024.08.08.607129 — neuroscience — Posted on 2024-08-09
3613 Engineering the plant intracellular immune receptor Sr50 to restore recognition of the AvrSr50 escape mutant
Seong, K.; Wei, W.; Vega, B.; Dee, A.; Ramirez-Bernardino, G.; Kumar, R.; Parra, L.; Krasileva, K.
10.1101/2024.08.07.607039 — plant biology — Posted on 2024-08-09
3615 Dihydroxyhexanoic acid biosynthesis controls turgor in pathogenic fungi
Kumakura, N.; Motoyama, T.; Miyazawa, K.; Nogawa, T.; Yonehara, K.; Sakai, K.; Ishihama, N.; Matsumori, K.; Gan, P.; Koshino, H.; Fukuma, T.; O'Connell, R. J.; Shirasu, K.
10.1101/2024.08.07.606736 — plant biology — Posted on 2024-08-09
3616 Tumor localization strategies of multi-cancer early detection tests: a quantitative assessment
Tyson, C.; Li, K. H.; Cao, X.; O'Brien, J. M.; Fishman, E. K.; O'Donnell, E. K.; Duran, C.; Parthasarathy, V.; Rego, S. P.; Choudhry, O. A.; Beer, T. M.
10.1101/2024.08.07.607020 — cancer biology — Posted on 2024-08-09
3617 Single-cell multidimensional profiling of tumor cell heterogeneity in supratentorial ependymomas
Jeong, D.; Danielli, S. G.; Maass, K. K.; Ghasemi, D. R.; Tetzlaff, S. K.; Reyhan, E.; Oliveira de Biagi-Junior, C. A.; Neyazi, S.; Nascimento, A.; Haase, R.; Lo Cascio, C.; Englinger, B.; Jiang, L.; Nguyen, C. M.; Baumgartner, A. C.; Castellani, S.; Rozowsky, J. S.; Hack, O. A.; Shaw, M. L.; Lotsch-Gojo, D.; Bruckner, K.; Pfister, S. M.; Kool, M.; Nowakowski, T. J.; Gojo, J.; Baird, L.; Alexandrescu, S.; Pajtler, K. W.; Venkataramani, V.; Filbin, M. G.
10.1101/2024.08.07.607066 — cancer biology — Posted on 2024-08-09
3618 Renal cancer cells acquire immune surface protein through trogocytosis and horizontal gene transfer
Marcarian, H. Q.; Sivakoses, A.; Arias, A. M.; Ihedioha, O.; Bishop, M. C.; Lee, B. R.; Bothwell, A. L. M.
10.1101/2024.08.07.607036 — cancer biology — Posted on 2024-08-09
3622 Structure and function of the human apoptotic scramblase Xkr4
Accardi, A.; Chakraborty, S.; Feng, Z.; Lee, S.; Alvarenga, O. E.; Panda, A.; Bruni, R.; Khelashvili, G.; Gupta, K.
10.1101/2024.08.07.607004 — biophysics — Posted on 2024-08-09
3628 Optimizing the detection of biological signals through a semi-automated feature selection tool
Arini, G.; Mencucini, L. G. S.; de Felicio, R.; Feitosa, L. G. P.; Rezende-Teixeira, P.; Tsuji, H.; Pilon, A.; Pinto, D. R.; Costa-Lotufo, L. V.; Lopes, N. P.; Trivella, D. B.; da Silva, R. R.
10.1101/2024.08.07.607073 — bioinformatics — Posted on 2024-08-09
3629 Retinal thermometry in-vivo using phase-sensitive optical coherence tomography
Zhuo, Y.; Bhuckory, M. B.; Li, H.; Junya, H.; Pham-Howard, D.; Veysset, D.; Ling, T.; Palanker, D.
10.1101/2024.08.07.607046 — bioengineering — Posted on 2024-08-09
3632 The open to closed D-loop conformational switch determines length in filopodia-like actin bundles
Gadsby, J. R.; Savvas Ioannou, P.; Butler, R.; Mason, J.; Smith, A.; Dobramysl, U.; Chin, S.; Dobson, C.; Gallop, J.
10.1101/2024.08.09.607305 — biochemistry — Posted on 2024-08-09
3634 Nearly complete genome assembly of a critically endangered pine illuminates evolution and conservation of conifers
Zhang, R.-G.; Liu, H.; Shu, H.; Liu, D.-T.; Shang, H.-Y.; Jia, K.-H.; Wang, X.-Q.; Sun, W.-B.; Zhao, W.; Ma, Y.-P.
10.1101/2024.08.07.607108 — genomics — Posted on 2024-08-09
3635 Expanding kinetoplastid genome annotation through protein structure comparison
Trinidad-Barnech, J. M.; Sotelo-Silveira, J.; Fernandez Do Porto, D.; Smircich, P.
10.1101/2024.08.07.607044 — genomics — Posted on 2024-08-09
3636 Mixed outcomes in recombination rates after domestication: Revisiting theory and data
Bursell, M.; Rohilla, M.; Ramirez, L.; Cheng, Y.; Schwarzkopf, E. J.; Guerrero, R. F.; Heil, C. S.
10.1101/2024.08.07.607048 — evolutionary biology — Posted on 2024-08-09
3637 Revealing unseen dynamical regimes of ecosystems from population time-series data
Medeiros, L. P.; Sorenson, D. K.; Johnson, B. J.; Palkovacs, E. P.; Munch, S. B.
10.1101/2024.08.07.607005 — ecology — Posted on 2024-08-09
3640 Material Properties Of The Embryonic Small Intestine During Buckling Morphogenesis
Gao, J.; Martin, L. G.; Loffet, E. A.; Durel, J. F.; Oikonomou, P.; Nerurkar, N.
10.1101/2024.08.07.606927 — developmental biology — Posted on 2024-08-09
3641 Retinoic acid breakdown is required for proximodistal positional identity during amphibian limb regeneration
Duerr, T. J.; Miller, M.; Kumar, S.; Bakr, D.; Griffiths, J. R.; Gautham, A. K.; Douglas, D.; Voss, S. R.; Monaghan, J. R.
10.1101/2024.08.07.607055 — developmental biology — Posted on 2024-08-09
3643 Cellular context specific tuning of actomyosin ring contractility within a common cytoplasm
Linehan, J.; Zampetaki, A.; Werner, M.; Heck, B.; Maddox, P.; Furthauer, S.; Maddox, A. S.
10.1101/2024.08.08.607200 — cell biology — Posted on 2024-08-09
3645 Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis
Kim, A.; McMullen, M. R.; Bellar, A.; Streem, D.; Dasarathy, J.; Welch, N.; Dasarathy, S.
10.1101/2024.08.07.607014 — immunology — Posted on 2024-08-09
3646 Overventilation-induced airspace acidification increases susceptibility to Pseudomonas pneumonia
Felten, M.; Tan, C.; Ferencik, S.; Li, J.; Letsiou, E.; Lienau, J.; Muller-Redetzky, H.; Hocke, A.; Bromel, T. C.; Gruber, A. D.; Krishnamoorthy, G.; Ochs, M.; Brandenberger, C.; Zhang, Q.; Kuebler, W. M.; Witzenrath, M.
10.1101/2024.08.07.603041 — immunology — Posted on 2024-08-09
3648 Outer hair cells stir cochlear fluids
Lee, C.; Shokrian, M.; Henry, K. S.; Carney, L.; Holt, J. C.; Nam, J.-H.
10.1101/2024.08.07.607009 — neuroscience — Posted on 2024-08-09
3650 Effects of serotonergic psychedelics on synaptogenesis and immediate early genes expression - comparison with ketamine, fluoxetine and lithium
Vella, Y.; Syrova, K.; Petruskova, A.; Koutrouli, I.; Kutna, V.; Pala, J.; Nikolic, M.; Sichova, K.; Mazoch, V.; Jurok, R.; Kuchar, M.; Bendova, Z.; Palenicek, T.
10.1101/2024.08.07.606965 — neuroscience — Posted on 2024-08-09
3652 Targeted Time-Varying Functional Connectivity
Alonso, S.; Cocchi, L.; Hearne, L. J.; Shine, J. M.; Vidaurre, D.
10.1101/2024.08.07.606804 — neuroscience — Posted on 2024-08-09
3659 Temporal changes in surface tension guide the accurate asymmetric division of Arabidopsis zygotes
Kang, Z.; Nakagawa, S.; Matsumoto, H.; Ishimoto, Y.; Nonoyama, T.; Hanaki, Y.; Tsugawa, S.; Ueda, M.
10.1101/2024.08.07.605794 — plant biology — Posted on 2024-08-09
3660 CRISPR-Cas9 mediated deletions of FvMYB46 reduces fruit set and biosynthesis of flavonoids in Fragaria vesca
Rai, A.; Skarn, M. N.; Tengs, T.; Elameen, A.; Amundsen, M. R.; Bjora, O. S.; Haugland, L. K.; Yakovlev, I. A.; Brurberg, M. B.; Thorstensen, T.
10.1101/2024.08.07.607017 — plant biology — Posted on 2024-08-09
3668 Boundary-Sensing Mechanism in Branched Microtubule Networks
Zaferani, M.; Song, R.; Wingreen, N. S.; Stone, H. A.; Petry, S.
10.1101/2024.08.07.606992 — bioengineering — Posted on 2024-08-09
3671 Releasing the octoPus, an open-source digital tool to promote Integrated Pest Management
Bregaglio, S. U. M.; Rossi, E.; Ascari, L.; Mongiano, G.; Del Cavallo, E.; Bajocco, S.; Manici, L. M.; Pepe, A. G.; Bassi, C.; Tiso, R.; Pietrangeli, F.; Cattaneo, G.; Nigro, C.; Gerardi, M. S.; Bussotti, S.; Sanchioni, A.; Tognetti, D.; Sandra, M.; De Lillo, I.; Framarin, P.; Di Ferdinando, S.; Bugiani, R.
10.1101/2024.08.07.606987 — ecology — Posted on 2024-08-09
3673 All-Diamond Boron-Doped Microelectrodes for Neurochemical Sensing with Fast-Scan Cyclic Voltammetry
Gupta, B.; Kepros, B.; Landgraf, J. B.; Becker, M. F.; Li, W.; Purcell, E. K.; Siegenthaler, J. R.
10.1101/2024.08.07.606919 — neuroscience — Posted on 2024-08-09
3678 Chromatin conformation dynamics during CD4+ T cell activation implicates autoimmune disease-associated genes and regulatory elements
Pahl, M. C.; Sharma, P.; Thomas, R. M.; Thompson, Z.; Mount, Z.; Pippin, J.; Morawski, P. A.; Su, C.; Campbell, D. J.; Grant, S. F.; Wells, A. D.
10.1101/2023.04.05.535731 — immunology — Posted on 2024-08-09
3681 Linking brain-heart interactions to emotional arousal in immersive virtual reality
Fourcade, A.; Klotzsche, F.; Hofmann, S. M.; Mariola, A.; Nikulin, V.; Villringer, A.; Gaebler, M.
10.1101/2024.01.04.574165 — neuroscience — Posted on 2024-08-09
3682 Macroscale traveling waves evoked by single-pulse stimulation of the human brain
Campbell, J. M.; Davis, T. S.; Nesterovich Anderson, D.; Arain, A.; Davis, Z.; Inman, C. S.; Smith, E. H.; Rolston, J. D.
10.1101/2023.03.27.534002 — neuroscience — Posted on 2024-08-09
3683 PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
Liu, F.; Liu, W.; Tan, Y.; Shang, Y.; Ling, S.; Jiang, X.; Zhang, Z.; Sun, S.; Xie, P.
10.1101/2024.08.06.606911 — cell biology — Posted on 2024-08-09
3685 From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways
Gu, S.; Shao, Y.; Rehm, K.; Bigler, L.; Zhang, D.; He, R.; Xu, R.; Shao, J.; Jousset, A.; Friman, V.-P.; Bian, X.; Wei, Z.; Kummerli, R.; Li, Z.
10.1101/2023.10.30.564663 — genomics — Posted on 2024-08-09
3688 Local neurovascular coupling in the amygdala is responsible for context-dependent emotional adjustment
Ruan, J.; Quan, X.; Xie, H.; Zhang, Y.; Zhang, D.; Wang, W.; Zhao, B.; Lu, D.; Jia, J.-M.
10.1101/2023.02.13.527949 — neuroscience — Posted on 2024-08-09
3690 Deletion of endocannabinoid synthesizing enzyme DAGLα from cerebellar Purkinje cells decreases social preference and elevates anxiety
Smith, G.; McCoy, K.; Viana Di Prisco, G.; Kuklish, A.; Grant, E.; Bhat, M.; Atwood, B.; Mackie, K.; Kalinovsky, A.
10.1101/2024.08.08.607068 — neuroscience — Posted on 2024-08-08
3691 No single PCR test is sufficient to determine parvovirus IHHNV presence in or impact on farmed shrimp production
Sritunyalucksana, K.; Sanguanrut, P.; Srisala, J.; Thawonsuwan, J.; Saleetid, N.; Vanichviriyakit, R.; Chotwiwatthanakun, C.; FLEGEL, T. W.; Taengchaiyaphum, S.
10.1101/2023.09.08.556791 — zoology — Posted on 2024-08-08
3693 The nuclear-cytoplasmic ratio controls the cell cycle period in compartmentalized frog egg extract
Pineros, L.; Frolov, N.; Ruiz-Reynes, D.; Van Eynde, A.; Cavin-Meza, G. J.; Heald, R.; Gelens, L.
10.1101/2024.07.28.605512 — biophysics — Posted on 2024-08-08
3695 Crystal Structure of the 4-Hydroxybutyryl-CoA Synthetase (ADP-forming) from Nitrosopumilus maritimus
Johnson, J. A.; Tolar, B. B.; Tosun, B.; Yoshikuni, Y.; Francis, C. A.; Wakatsuki, S.; Demirci, H.
10.1101/2023.07.14.549078 — biophysics — Posted on 2024-08-08
3699 Generative AI for Cardiac Organoid Florescence Generation
Kandula, A. K. R.; Phamornratanakun, T.; Gomez, A. H.; El-Mokahal, M.; Ma, Z.; Feng, Y.; Yang, H.
10.1101/2024.01.15.575724 — bioengineering — Posted on 2024-08-08
3700 Dual-Action Kinase Inhibitors Influence p38α MAP Kinase Dephosphorylation
Stadnicki, E.; Ludewig, H.; Kumar, R. P.; Wang, X.; Qiao, Y.; Kern, D.; Bradshaw, N.
10.1101/2024.05.15.594272 — biochemistry — Posted on 2024-08-08
3701 Comparative analysis of tardigrade locomotion across life stage, species, and pharmacological treatment
Anderson, E. M.; Houck, S. G.; Conklin, C. L.; Tucci, K. L.; Rodas, J. D.; Mori, K. E.; Armstrong, L. J.; Illingworth, V. B.; Lo, T.-W.; Woods, I. G.
10.1101/2024.05.24.595396 — animal behavior and cognition — Posted on 2024-08-08
3702 Learning sequence-based regulatory dynamics in single-cell genomics
Ibarra, I. L.; Schneeberger, J.; Erdogan, E.; Redl, L.; Martens, L.; Klein, D.; Aliee, H.; Theis, F. J.
10.1101/2024.08.07.605876 — genomics — Posted on 2024-08-08
3703 Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy
Lichauco, C.; Foss, E. J.; Gatbonton-Schwager, T.; Athow, N. F.; Lofts, B.; Acob, R.; Taylor, E.; Marquez, J. J.; Lao, U.; Miles, s.; Bedalov, A.
10.1101/2024.03.21.586113 — genetics — Posted on 2024-08-08
3704 Loss of cped1 does not affect bone and lean mass in zebrafish
Alvarado, K.; Tang, W. J.; Watson, C. J.; Ahmed, A. R.; Gomez, A. E.; Donaka, R.; Amemiya, C. T.; Karasik, D.; Hsu, Y.-H.; Kwon, R. Y.
10.1101/2024.07.10.601974 — genetics — Posted on 2024-08-08
3705 Mint/X11 PDZ domains from non-bilaterian animals recognize and bind CaV2 calcium channel C-termini in vitro .
Harracksingh, A. N.; Singh, A.; Mayorova, T.; Bejoy, B.; Hornbeck, J.; Elkhatib, W.; McEdwards, G.; Gauberg, J.; Taha, A. R. W.; Islam, I. M.; Erclik, T.; Currie, M. A.; Noyes, M.; Senatore, A.
10.1101/2024.02.26.582151 — evolutionary biology — Posted on 2024-08-08
3709 An atypical basement membrane forms a midline barrier during left-right asymmetric gut development in the chicken embryo
Demler, C. A.; Lawlor, J. C.; Yelin, R.; Llivichuzcha-Loja, D.; Shaulov, L.; Kim, D. S.; Stewart, M. A.; Lee, F.; Shylo, N. A.; Trainor, P.; Schultheiss, T. M.; Kurpios, N. A.
10.1101/2023.08.15.553395 — developmental biology — Posted on 2024-08-08
3710 Ligand-Dependent Mechanisms of C-C Chemokine Receptor 5 (CCR5) Trafficking Revealed by APEX2 Proximity Labeling Proteomics
Gu, S.; Maurya, S.; Lona, A.; Borrega-Roman, L.; Salanga, C.; Gonzalez, D. J.; Kufareva, I.; Handel, T.
10.1101/2023.11.01.565224 — cell biology — Posted on 2024-08-08
3713 LitGene: a transformer-based model that uses contrastive learning to integrate textual information into gene representations
Jararweh, A.; Macaulay, O.; Arredondo, D.; Oyebamiji, O.; Hu, Y.; Tafoya, L.; Zhang, Y.; Virupakshappa, K.; Sahu, A.
10.1101/2024.08.07.606674 — bioinformatics — Posted on 2024-08-08
3715 HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging
Day, J. H.; Della Santina, C. M.; Maretich, P.; Auld, A. L.; Schneider, K. K.; Shin, T.; Boyden, E. S.; Boyer, L. A.
10.1101/2023.02.07.527509 — bioengineering — Posted on 2024-08-08
3717 Phlorotannin rich Ascophyllum nodosum seaweed extract inhibits influenza infection
Mega, D. F.; Sharma, P.; Kipar, A.; Hetzel, U.; Bramwell, C.; Meritt, A.; Wright, S.; Plummer, C.; Urbanowicz, R. A.; Stewart, J. P.
10.1101/2024.08.08.606782 — microbiology — Posted on 2024-08-08
3718 Plasmid-chromosome transcriptional crosstalk in multidrug resistant clinical enterobacteria
Toribio-Celestino, L.; Calvo-Villamanan, A.; Herencias, C.; Alonso-del Valle, A.; Sastre-Dominguez, J.; Quesada, S.; Mazel, D.; Rocha, E. P. C.; Fernandez-Calvet, A.; San Millan, A.
10.1101/2024.08.08.607126 — microbiology — Posted on 2024-08-08
3722 Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice
McFadden, S. A.; Peck, M. R.; Sime, L. N.; Cox, M. F.; Ikiz, E. D.; Findley, C. A.; Quinn, K.; Fang, Y.; Bartke, A.; Hascup, E. R.; Hascup, K. N.
10.1101/2024.03.26.586836 — neuroscience — Posted on 2024-08-08
3723 Insights into the role of dopamine in rhizosphere microbiome assembly
Ding, Y.; Vogel, H. K.; Zhai, Y.; Carlson, H. K.; Andeer, P. F.; Novak, V.; Kim, N.; Bowen, B. P.; Golini, A. N.; Kosina, S. M.; Coleman-Derr, D.; Vogel, J. P.; Northen, T. R.
10.1101/2024.08.07.607067 — plant biology — Posted on 2024-08-08
3725 A Versatile Antibody Capture System that Drives Precise In Vivo Delivery of mRNA loaded Lipid Nanoparticles and Enhances Gene Expression
Chen, M.; Yuen, D.; McLeod, V. M.; Yong, K. W.; Smyth, C. H.; Rossi Herling, B.; Payne, T.; Fabb, S.; Belousoff, M. J.; Algarni, A.; Sexton, P. M.; Porter, C. J. H.; Pouton, C. W.; Johnston, A. P. R.
10.1101/2024.08.07.607101 — bioengineering — Posted on 2024-08-08
3731 Detection of genome structural variation in normal cells and tissues by single molecule sequencing
Heid, J.; Huang, Z.; Lee, M.; Makhortov, S.; Pan, E.; Montagna, C.; Sun, S. Y.; Vijg, J.; Maslov, A. Y.
10.1101/2024.08.08.607188 — genomics — Posted on 2024-08-08
3733 Mechanistic basis of lineage restriction
Wu, B.; Lee, J. H.; Foshay, K. M.; Zhang, L.; Fernandes, C. J.; Gao, B.; Dou, X.; Zhang, C. Z.; Fan, G.; Xiao, B. X.; Lahn, B. T.
10.1101/2024.08.07.606262 — developmental biology — Posted on 2024-08-08
3736 Biallelic Loss of Molecular Chaperone Molecule AIP Results in a Novel Severe Multisystem Disease Defined by Defective Proteostasis
Korbonits, M.; Wang, X.; Barry, S.; Lim, C.; Suleyman, O.; De-Tito, S.; Begum, N.; Vignola, M. L.; Hall, C.; Perna, L.; Chapple, P.; Henson, S.; Morales, V.; Bianchi, K.; Edvardsson, V. O.; Ragnarsson, K. A.; Kristinsdottir, V. E.; Debeer, A.; Sleyp, Y.; Zinchenko, R.; Anderson, G.; Duchen, M.; Singh, K.; Chung, C.-Y.; Yuan, Y.; Patel, S.; Aksoy, E.; Borovikov, A. O.; Bjornsson, H. T.; Van Esch, H.; Czibik, G.; Tooze, S.; Brennan, C. H.; Haworth, O.
10.1101/2024.08.08.604602 — molecular biology — Posted on 2024-08-08
3741 Commensal Yeast Promotes Salmonella Typhimurium Virulence
Jaswal, K.; Todd, O. A.; Flores Audelo, R. C.; Santus, W.; Paul, S.; Singh, M.; Miao, J.; Underhill, D. M.; Peters, B. M.; Behnsen, J.
10.1101/2024.08.08.606421 — microbiology — Posted on 2024-08-08
3743 Design of a Soluble Multivalent Notch Agonist
Mout, R.; Jing, R.; Egan, E.; Eisenach, H.; Najia, M. A.; Hensch, L.; Bingham, T.; Kononov, M.; Gunage, R.; Zhao, Y.; Edman, N. I.; SCHLAEGER, T.; Zon, L. I.; North, T. E.; Lendahl, U.; Baker, D.; Blacklow, S.; Daley, G. Q.
10.1101/2024.08.07.607099 — synthetic biology — Posted on 2024-08-08
3744 A synthetic cell-free pathway for biocatalytic upgrading of one-carbon substrates
Landwehr, G. M.; Vogeli, B.; Tian, C.; Singal, B.; Gupta, A.; Lion, R.; Sargent, E. H.; Karim, A. S.; Jewett, M. C.
10.1101/2024.08.08.607227 — synthetic biology — Posted on 2024-08-08
3745 Potent LILRB1 D1D2-containing antibodies inhibit RIFIN-mediated immune evasions
Wang, Y.; Tang, H.; Wang, W.; Li, M.; Zhu, C.; Dai, H.; Zhao, H.; Wu, B.; Wang, J.
10.1101/2024.08.08.607148 — biochemistry — Posted on 2024-08-08
3746 Genomic sequencing to detect cross-breeding quality in dogs: an example studying disorders in sexual development
de Gennaro, L.; Burgio, M.; Lacalandra, G. M.; Petronella, F.; L'Abbate, A.; Ravasini, F.; Trombetta, B.; Rizzo, A.; Ventura, M.; Cicirelli, V.
10.1101/2024.08.07.606952 — genomics — Posted on 2024-08-08
3753 Asymmetric genome merging leads to gene expression novelty through nucleo-cytoplasmic disruptions and transcriptomic shock in Chlamydomonas triploids
Prost-Boxoen, L.; Bafort, Q.; Van de Vloet, A.; Almeida-Silva, F.; Thet Paing, Y.; Casteleyn, G.; D'hondt, S.; De Clerck, O.; Van de Peer, Y.
10.1101/2024.08.06.604315 — evolutionary biology — Posted on 2024-08-08
3754 Long-term tree population growth can predict woody encroachment patterns
Shriver, R. K.; Pletcher, E.; Biondi, F.; Urza, A. K.; Weisberg, P. J.
10.1101/2024.04.07.588197 — ecology — Posted on 2024-08-08
3755 Using integrated wildlife monitoring for quantifying the impact of emerging Bagaza virus in red-legged partridges in Portugal, 2012-2024
Queiros, J.; Costa, J. B.; Mello, G.; Fontoura-Goncalves, C.; Hofle, U.; Gortazar, C.; Alves, P. C.; Acevedo, P.; Goncalves, D.
10.1101/2024.08.07.606962 — ecology — Posted on 2024-08-08
3759 Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.
Hoffner, G.; Castro, P.; Uhrig, L.; Signorelli, C. M.; Dupont, M.; Tasserie, J.; Destexhe, A.; Cofre, R.; Sitt, J.; Jarraya, B.
10.1101/2024.03.27.586806 — neuroscience — Posted on 2024-08-08
3763 Patient-specific gene networks reveal novel subtypes and predictive biomarkers in lung cancer
Lopez-Sanchez, P.; Avila-Moreno, F.; Hernandez-Lemus, E.; Kuijjer, M. L.; Espinal-Enriquez, J.
10.1101/2024.08.06.606802 — systems biology — Posted on 2024-08-08
3765 Study on the phenotypic diversity and comprehensive evaluation analysis of 43 ornamental peonies of Sect. Paeonia.
Cao, H.; Xu, S.; Liu, M.; Jiang, S.; Ma, L.; Wu, J.; Zhang, X.; Kong, L.; Ren, W.; Liu, Z.; Chen, X.; Ma, W.; Liu, X.
10.1101/2024.08.06.606934 — plant biology — Posted on 2024-08-08
3767 Two TAL effectors of Xanthomonas citri pv. malvacearum target GhSWEET15 as the susceptibility genes for bacterial blight of cotton
Shah, S. M. A.; Haq, F.; Huang, K.; Wang, Q.; Liu, L.; Li, Y.; Wang, Y.; Khan, A.; Yang, R.; Khojasteh, M.; Xu, X.; Xu, Z.; Chen, G.
10.1101/2024.08.06.606744 — pathology — Posted on 2024-08-08
3768 Deep lipidomic profiling reveals sex dimorphism of lipid metabolism in fibro-calcific aortic valve disease
Prabutzki, P.; Woelk, M.; Boettner, J.; Ni, Z.; Werner, S.; Thiele, H.; Schiller, J.; Buettner, P.; Schlotter, F.; Fedorova, M.
10.1101/2024.08.07.606946 — pathology — Posted on 2024-08-08
3769 Disruption of Circadian Clock Induces Abnormal Mammary Morphology and Aggressive Basal Tumorigenesis by Enhancing LILRB4 Signaling
Ogunlusi, O.; Sarkar, M.; Chakrabarti, A.; Boland, D.; Nguyen, T.; Sampson, J.; Nguyen, C.; Falis, D.; Jones-Hall, Y.; Fu, L.; Mallick, B.; Keene, A.; Jones, J.; Sarkar, T. R.
10.1101/2024.03.19.585534 — cancer biology — Posted on 2024-08-08
3770 Tokenized and Continuous Embedding Compressions of Protein Sequence and Structure
Lu, A. X.; Yan, W.; Yang, K. K.; Gligorijevic, V.; Cho, K.; Abbeel, P.; Bonneau, R.; Frey, N.
10.1101/2024.08.06.606920 — bioinformatics — Posted on 2024-08-08
3771 Accelerated Limbal Epithelial Differentiation of Human Induced Pluripotent Stem Cells Using a Defined Keratinocyte Serum-Free Medium
Roshandel, D.; Alvarez-Palomo, B.; Zaw, K.; Zhang, D.; Edel, M. J.; Wong, E. N.; Wiffen, S.; Chen, F. K.; Morgan, W. H.; McLenachan, S.
10.1101/2024.08.06.606916 — bioengineering — Posted on 2024-08-08
3773 SARM1 orthosteric base exchange inhibitors cause subinhibitory SARM1 activation
Leahey, R.; Weber, M.; Cho, C. H.; Hur, S.; Cramer, A.; Manzanares, K.; Babin, B.; Boenig, G.; Kring, T.; Liu, L.; Cui, Y.; Ganti, A.; Evans, J. P.; Nespi, M.; Ly, J.; Nugent, A. A.; Green, S.; Chan, B.; Hoogenraad, C. C.; Delwig, A.; Hinz, F. I.
10.1101/2024.08.06.606489 — neuroscience — Posted on 2024-08-08
3774 Adenosine signaling in glia modulates metabolic state-dependent behavior in Drosophila
De Backer, J.-F.; Karges, T.; Papst, J.; Coman, C.; Ahrends, R.; Xu, Y. Y.; Garcia-Ceceres, C.; Grunwald Kadow, I. C.
10.1101/2024.08.07.606811 — neuroscience — Posted on 2024-08-08
3775 Thermally-induced neuronal plasticity that mediates heat tolerance
Siemens, J.; Ambroziak, W.; Nencini, S.; Pohle, J.; Pino, G.; Lundh, S.; Arauja-Sousa, C.; Goetze, L. I. L.; Schrenk-Siemens, K.; Manoj, G.; Herrera, M.; Acuna, C.
10.1101/2024.08.06.606929 — neuroscience — Posted on 2024-08-08
3776 Stochastic Wiring of Cell Types Enhances Fitness by Generating Phenotypic Variability
Lachi, D.; Huang, A.; Mavor-Parker, A. N.; Ghosh, A.; Zador, A.; Richards, B.
10.1101/2024.08.07.606541 — neuroscience — Posted on 2024-08-08
3777 Neural mechanisms of credit assignment for delayed outcomes during contingent learning
Witkowski, P.; Rondot, L.; Kurth-Nelson, Z.; Garvert, M. M.; Dolan, R. J.; Behrens, T. E.; Boorman, E.
10.1101/2024.08.06.606895 — neuroscience — Posted on 2024-08-08
3779 Persistent changes in nociceptor translatomes govern hyperalgesic priming in mouse models
Sankaranarayanan, I.; Kume, M.; Mohammed, A.; Mwirigi, J. M.; Inturi, N. N.; Munro, G.; Petersen, K. A.; Tavares-Ferreira, D.; Price, T. J.
10.1101/2024.08.07.606891 — neuroscience — Posted on 2024-08-08
3782 Loss of multi-level 3D genome organization during breast cancer progression
Rossini, R.; Oshaghi, M.; Nekrasov, M.; Bellanger, A.; Domaschenz, R.; Dijkwel, Y.; Abdelhalim, M.; Collas, P.; Tremethick, D.; Paulsen, J.
10.1101/2023.11.26.568711 — genomics — Posted on 2024-08-08
3784 A spatial threshold for astrocyte calcium surge
Lines, J.; Baraibar, A. M.; Nanclares, C.; Martin, E.; Aguilar, J. d. l. R.; Kofuji, P.; Navarrete, M.; Araque, A.
10.1101/2023.07.18.549563 — neuroscience — Posted on 2024-08-08
3785 Unifying regulatory motifs in endocrine circuits
Raz, M.; Glass, D. S.; Milo, T.; Kohanim, Y. K.; karin, O.; Tendler, A.; Mayo, A.; Alon, U.
10.1101/2024.08.06.606903 — systems biology — Posted on 2024-08-08
3787 SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma
Elaimy, A. L.; El-Derany, M. O.; James, J.; Wang, Z.; Pearson, A. N.; Holcomb, E. A.; Huber, A. K.; Gijon, M.; Bell, H. N.; Sanghvi, V. R.; Frankel, T. L.; Su, G. L.; Tapper, E. B.; Tai, A. W.; Ramnath, N.; Centonze, C. P.; Dobrosotskaya, I.; Moeller, J. A.; Bryant, A. K.; Elliott, D. A.; Choi, E.; Evans, J. R.; Cuneo, K. C.; Fitzgerald, T. J.; Wahl, D. R.; Morgan, M. A.; Chang, D. T.; Wicha, M. S.; Lawrence, T. S.; Shah, Y. M.; Green, M. D.
10.1101/2024.08.06.606899 — cancer biology — Posted on 2024-08-08
3790 Engineered Protein-G variants for plug-and-play applications
Slezak, T.; O'Leary, K. M.; Li, J.; Rohaim, A.; Davydova, E. K.; Kossiakoff, A. A.
10.1101/2024.08.06.606809 — bioengineering — Posted on 2024-08-08
3791 Rapid phenotypic and genotypic change in a laboratory schistosome population
Jutzeler, K. S.; Platt, R. N.; Li, X.; Morales, M.; Diaz, R.; Le Clec'h, W.; Chevalier, F.; Anderson, T. J.
10.1101/2024.08.06.606850 — genomics — Posted on 2024-08-08
3792 Phylogenomic prediction of interaction networks in the presence of gene duplication
Gatts, T. C.; deRoux, C.; Lane, L. E.; Berggren, M.; Rehmann, E. A.; Zak, E.; Bartel, T.; L'Argent, L.; Sloan, D. B.; Forsythe, E. S.
10.1101/2024.08.06.606904 — genomics — Posted on 2024-08-08
3796 TBK1 and IKKϵ protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanism
Sun, N. D.; Carr, A. R.; Erica, K. N.; Chawla, Y.; Zhong, J.; Guttormson, M. C.; Chan, M.; Hsu, M. A.; Dong, H.; Bogunovic, D.; Pandey, A.; Rogers, L. M.; Ting, A. T.
10.1101/2024.08.06.606693 — immunology — Posted on 2024-08-08
3798 The heme-scavenger, hemopexin, protects against fungal lung injury by mitigating NETosis: an experimental and computational study.
Qu, G.; Ribeiro, H. A. L.; Solomon, A. L.; Vieira, L. S.; Goddard, Y.; Diodati, N. G.; Lazarte, A. V.; Wheeler, M.; Laubenbacher, R.; Mehrad, B.
10.1101/2024.08.06.606866 — immunology — Posted on 2024-08-08
3803 Microglia determine beta-amyloid plaque burden but are non-essential for downstream pathology
Li, M.; Holt, K.; Ridley, K.; Qiu, J.; Haddow, K.; Vasoya, D.; He, X.; Tulloch, J.; King, D.; Hume, D. A.; Pridans, C.; Dando, O. R.; Spires-Jones, T. L.; Hardingham, G. E.
10.1101/2024.08.06.606795 — neuroscience — Posted on 2024-08-08
3804 Hierarchical optimization of biochemical networks
Viswan, N. A.; Tribut, A.; Gasparyan, M.; Radulescu, O.; Bhalla, U. S.
10.1101/2024.08.06.606818 — systems biology — Posted on 2024-08-08
3805 Predicting plasmodesmata-mediated interface permeability and intercellular diffusion
Liesche, J.; Li, J.; Martens, H. J.; Gao, C.; Subroto, C.; Schulz, A.; Deinum, E.
10.1101/2024.08.06.606906 — plant biology — Posted on 2024-08-08
3807 Cysteine depletion triggers adipose tissue thermogenesis and weight-loss.
Lee, A.; Orliaguet, L.; Youm, Y.-H.; Maeda, R.; Dlugos, T.; Lei, Y.; Coman, D.; Shchukina, I.; Andhey, P. S.; Smith, S. R.; Ravussin, E.; Stadler, K.; Hyder, F.; Artyomov, M. N.; Sugiura, Y.; Dixit, V. D.
10.1101/2024.08.06.606880 — physiology — Posted on 2024-08-08
3808 Timing anti-PD-L1 checkpoint blockade immunotherapy to enhance tumor irradiation
Lee, S. S.-Y.; Pagacz, J.; Averbek, S.; Scholten, D.; Liu, Y.; Kron, S. J.
10.1101/2024.08.06.606845 — cancer biology — Posted on 2024-08-08
3809 Therapeutic targeting of Syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
Takeda, M.; Theardy, M. S.; Sorokin, A.; Coker, O.; Kanikarla, P.; Chen, S.; Yang, Z.; Nguyen, P.; Wei, Y.; Yao, J.; Wang, X.; Yan, L.; Jin, Y.; Cai, Y.; Paku, M.; Chen, Z.; Li, K. Z.; Citron, F.; Tomihara, H.; Gao, S.; Deem, A. K.; Zhao, J.; Wang, H.; Hanash, S.; DePinho, R. A.; MAITRA, A.; Draetta, G. F.; Ying, H.; Kopetz, S.; Yao, W.
10.1101/2024.08.06.606865 — cancer biology — Posted on 2024-08-08
3810 Integrin blocking peptide reverses immunosuppression in experimental gliomas and improves anti-PD-1 therapy outcome
Ellert-Miklaszewska, A.; Pilanc-Kudlek, P.; Poleszak, K.; Roura, A.-J.; Cyranowski, S.; Ghosh, M.; Baluszek, S.; Pasierbinska, M.; Gielniewski, B.; Swatler, J.; Hovorova, Y.; Wojnicki, K.; Kaminska, B.
10.1101/2024.08.06.606798 — cancer biology — Posted on 2024-08-08
3811 Heat flows solubilize apatite to boost phosphate availability for prebiotic chemistry
Matreux, T.; Schmid, A.; Rappold, M.; Weller, D.; Caliskanoglu, A. Z.; Moore, K. R.; Bosak, T.; Dingwell, D. B.; Karaghiosoff, K.; Guyot, F.; Scheu, B.; Braun, D.; Mast, C. B.
10.1101/2024.08.06.606769 — biophysics — Posted on 2024-08-08
3812 Nano-org, a functional resource for single-molecule localisation microscopy data
Shirgill, S.; Nieves, D. J.; Pike, J. A.; Ahmed, M. A.; Baragilly, M. H. H.; Savoye, K.; Worboys, J.; Hazime, K.; Garcia, A.; Williamson, D. J.; Rubin-Delanchy, P.; Peters, R.; Davis, D. M.; Henriques, R.; Lee, S. F.; Owen, D. M.
10.1101/2024.08.06.606779 — biophysics — Posted on 2024-08-08
3819 Optics-free reconstruction of 2D images via DNA barcode proximity graphs
Liao, H.; Kottapalli, S.; Huang, Y.; Chaw, M.; Gehring, J.; Waltner, O.; Phung-Rojas, M.; Daza, R. M.; Matsen, F. A.; Trapnell, C.; Shendure, J.; Srivatsan, S. R.
10.1101/2024.08.06.606834 — genomics — Posted on 2024-08-08
3820 VC2 regulates baseline vicine content in faba bean
Ugwuanyi, S.; Makhoul, M.; Golicz, A.; Obermeier, C.; Snowdon, R.
10.1101/2024.08.06.606773 — genetics — Posted on 2024-08-08
3822 Genomic data reveal a north-south split and introgression history of blood fluke (Schistosoma haematobium) populations from across Africa
Platt, R. N.; Enabulele, E. E.; Adeyemi, E.; Agbugui, M. O.; Ajakaye, O. G.; Amaechi, E. C.; Ejikeugwu, C. E.; Igbeneghu, C.; Njom, V. S.; Dlamini, P.; Arya, G. A.; Diaz, R.; Rabone, M.; Allan, F.; Webster, B.; Emery, A.; Rollinson, D.; Anderson, T. J.
10.1101/2024.08.06.606828 — evolutionary biology — Posted on 2024-08-08
3826 p-IgGen: A Paired Antibody Generative Language Model
Turnbull, O. M.; Oglic, D.; Croasdale-Wood, R.; Deane, C. M.
10.1101/2024.08.06.606780 — immunology — Posted on 2024-08-08
3827 Microglia initially seed and later reshape amyloid plaques in Alzheimer's disease
Baligacs, N.; Albertini, G.; Borrie, S. C.; Serneels, L.; Pridans, C.; Balusu, S.; De Strooper, B.
10.1101/2024.08.06.606783 — neuroscience — Posted on 2024-08-08
3831 Somatosensory stimulation in moving mice
Parkes, I.; Schorscher-Petcu, A.; Gan, Q.; Browne, L. E.
10.1101/2024.08.06.606618 — neuroscience — Posted on 2024-08-08
3834 Differential Contributions of CA3 and Entorhinal Cortex Inputs to Ripple Patterns in the Hippocampus Under Cannabidiol
Aleman-Zapata, A.; Capitan, M. B. M.; Samanta, A.; Ozsezer, P.; Agarwal, K.; Adam, T.; Rayan, A.; Genzel, L.
10.1101/2024.08.06.606645 — neuroscience — Posted on 2024-08-08
3837 Variability of 7K and 11K SomaScan plasma proteomics assays
Candia, J.; Fantoni, G.; Delgado-Peraza, F.; Shehadeh, N.; Tanaka, T.; Moaddel, R.; Walker, K. A.; Ferrucci, L.
10.1101/2024.08.06.606813 — systems biology — Posted on 2024-08-08
3838 Diabetic liver-enriched secretory dipeptidyl peptidase 4 (DPP4) fuels gut inflammation via attenuation of autophagy
Athar, M.; Bhadury, R.; Gogoi, C.; Mishra, P.; Kumari, P.; Yadav, M.; Maras, J. S.; Ghorpade, D. S.
10.1101/2024.08.06.606776 — physiology — Posted on 2024-08-08
3840 PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis
Sisson, T. H.; Osterholzer, J. J.; Leung, L.; Basrur, V.; Nesvizhskii, A.; Subbotina, N.; Warnock, M.; Torrente, D.; Virk, A. Q.; Horowitz, J. C.; Migliorini, M.; Strickland, D. K.; Kim, K. K.; Huang, S. K.; Lawrence, D. A.
10.1101/2024.08.06.606812 — pathology — Posted on 2024-08-08
3841 Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation
Elkholi, I. E.; Robert, A.; Malouf, C.; Kuasne, H.; Drapela, S.; Macleod, G.; Hebert, S.; Pacis, A.; Calderon, V.; Kleinman, C. L.; Gomes, A. P.; Aguirre-Ghiso, J. A.; Park, M.; Angers, S.; Cote, J.-F.
10.1101/2023.08.02.551681 — cancer biology — Posted on 2024-08-08
3842 Deciphering tumour microenvironment and elucidating the origin of cancer cells in ovarian clear cell carcinoma
Kamaraj, U. S.; Gautam, P.; Cheng, T.; Chin, T. S.; Tay, S. K.; Ho, T. H.; Nadarajah, R.; Goh, R. C. H.; Wong, S. L.; Mantoo, S.; Busmanis, I.; Li, H.; Le, M. T.; Li, Q.-J.; Lim, E. H.; Loh, Y.-H.
10.1101/2024.08.06.606821 — cancer biology — Posted on 2024-08-08
3843 Controlling DNA-RNA strand displacement kinetics with base distribution
Ratajczyk, E. J.; Bath, J.; Sulc, P.; Doye, J. P. K.; Louis, A. A.; Turberfield, A. J.
10.1101/2024.08.06.606789 — biophysics — Posted on 2024-08-08
3847 RiboSnake - a user-friendly, robust, reproducible, multipurpose and documentation-extensive pipeline for 16S rRNA gene microbiome analysis
Doerr, A.-K.; Welling, J.; Doerr, A.; Gosch, J.; Moehlen, H.; Schmithausen, R.; Kehrmann, J.; Meyer, F.; Kraiselburd, I.
10.1101/2024.08.06.606757 — bioinformatics — Posted on 2024-08-08
3850 Predicting mutation-disease associations through protein interactions via deep learning
Li, X.; Cao, B.; Wang, J.; Meng, X.; Wang, S.; Huang, Y.; Petretto, E.; Song, T.
10.1101/2024.08.06.606730 — bioinformatics — Posted on 2024-08-08
3852 Optics-free Spatial Genomics for Mapping Mouse Brain Aging
Abdulraouf, A.; Jiang, W.; Xu, Z.; Zhang, Z.; Isakov, S.; Raihan, T.; Zhou, W.; Cao, J.
10.1101/2024.08.06.606712 — genomics — Posted on 2024-08-08
3857 Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility
Gomez-Frittelli, J.; Devienne, G. F.; Travis, L.; Kyloh, M. A.; Duan, X.; Hibberd, T. J.; Spencer, N. J.; Huguenard, J. R.; Kaltschmidt, J.
10.1101/2024.08.06.606748 — neuroscience — Posted on 2024-08-08
3858 Magnetoelectric Microrobots for Spinal Cord Injury Regeneration
Ye, H.; Zang, J.; Zhu, J.; Arx, D. v.; Pustovalov, V.; Mao, M.; Tang, Q.; Veciana, A.; Torlakcik, H.; Zhang, E.; Sevim, S.; Sanchis-Gual, R.; Chen, X.-Z.; Ahmed, D.; Sanchez-Vives, M. V.; Puigmarti-Luis, J.; Nelson, B. J.; Neuhauss, S. C. F.; Pane, S.
10.1101/2024.08.06.606378 — neuroscience — Posted on 2024-08-08
3862 Defining the cardiac fibroblast secretome in the healthy and infarcted mouse heart
Bahr, J.; Poschmann, G.; Jungmann, A.; Busch, M.; Ding, Z.; Zalfen, R.; Steinhausen, J.; Wachtmeister, T.; Rickert, D.; Lautwein, T.; Alter, C.; Amrute, J. M.; Lavine, K. J.; Koehrer, K.; Most, P.; Stuehler, K.; Hesse, J.; Schrader, J.
10.1101/2024.08.06.606146 — physiology — Posted on 2024-08-08
3864 Metabolic Reprogramming Driven by Ant2 -Targeting Augments T-Cell Function and Anti-Tumor Immunity
Yosef, O.; Cohen-Daniel, L.; Shamriz, O.; Bar-On, Z.; Saragovi, A.; Abramovich, I.; Agranovich, B.; Lutz, V.; Tam, J.; Permyakova, A.; Gottlieb, E.; Huber, M.; Berger, M.
10.1101/2024.04.21.590436 — immunology — Posted on 2024-08-08
3866 Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks
Sui, X.; Lo, J. A.; Luo, S.; He, Y.; Tang, Z.; Lin, Z.; Zhou, Y.; Wang, W. X.; Liu, J.; Wang, X.
10.1101/2024.08.05.606553 — genomics — Posted on 2024-08-08
3868 Paraptosome: A Novel Pathological Feature in Paraptotic Cell Death
Cui, X.; Zheng, H.; Li, H.; Zhang, F.; Yang, L.; Ni, J.; Wang, D.; Zhang, H.; Tang, P.; Li, R.; Zhang, Q.; Cui, M.
10.1101/2024.08.07.606501 — cell biology — Posted on 2024-08-08
3870 Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase
Roas, S. C.; Yagita, Y.; Murphy, P.; Kurzbauer, R.; Clausen, T.; Zavodszky, E.; Hegde, R. S.
10.1101/2024.08.07.607117 — cell biology — Posted on 2024-08-08
3871 ER-phagy drives age-onset remodeling of endoplasmic reticulum structure-function and lifespan
Donahue, E. K.; Hepowit, N. L.; Keuchel, B.; Mulligan, A. G.; Johnson, D. J.; Ellisman, M.; Arrojo e Drigo, R.; MacGurn, J. A.; Burkewitz, K.
10.1101/2024.08.07.607085 — cell biology — Posted on 2024-08-08
3872 Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana
Charura, N.; Llamas, E.; De Quattro, C.; Vilchez, D.; Nowack, M. K.; Zuccaro, A.
10.1101/2023.02.03.526420 — plant biology — Posted on 2024-08-08
3873 Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of oesophageal cancer
Ganguli, P.; Colomina-Basanta, C.; Acha-Sagrado, A.; Misetic, H.; Armero-Pineiro, M.; Mendez, A.; Zahra, A.; Devonshire, G.; Kelly, G.; Freeman, A.; Green, M.; Nye, E.; Bichisecchi, A.; Bonfanti, P.; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, ; Rodriguez-Justo, M.; Spencer, J.; Fitzgerald, R. C.; Ciccarelli, F. D.
10.1101/2024.01.24.576991 — cancer biology — Posted on 2024-08-08
3876 C-COMPASS: A Neural Network Tool for Multi-Omic Classification of Cell Compartments
Haas, D. T.; Trautmann, E. M.; Mao, X.; Gerl, M.; Klose, C.; Cheng, X.; Hasenauer, J.; Krahmer, N.
10.1101/2024.08.05.606647 — cell biology — Posted on 2024-08-08
3879 The two key substitutions in the chromophore environment of mKate2 to produce an enhanced FusionRed-like red fluorescent protein
Ruchkin, D. A.; Gavrikov, A. S.; Kolesov, D. V.; Gorokhovatsky, A. Y.; Chepurnykh, T. V.; Mishin, A. S.; Maximov, E. G.; Pletneva, N. V.; Pletnev, V. Z.; Pavlova, A. M.; Nikitin, V. A.; Lukyanov, K. A.; Bogdanov, A. M.
10.1101/2023.12.05.570295 — molecular biology — Posted on 2024-08-08
3880 Lipopeptide antibiotics disrupt interactions of undecaprenyl phosphate with UptA
Oluwole, A. O.; Kalmankar, N.; Guida, M.; Bennett, J. L.; Poce, G.; Bolla, J. R.; Robinson, C. V.
10.1101/2024.04.02.587717 — molecular biology — Posted on 2024-08-08
3881 SUMO4 promotes SUMO deconjugation required for DNA double-strand break repair.
Garvin, A. J.; Lanz, A.; MacKintosh, M.; Starowicz, K.; Ronson, G.; Walker, A.; Aghabi, Y.; MacKay, H.; Densham, R. R.; Leney, A.; Morris, J. R.
10.1101/2022.03.23.485504 — molecular biology — Posted on 2024-08-08
3882 Cell-free chromatin particles from dying cells promote the induction of an immune response in human lymphocytes
Shabrish, S.; Raghuram, G. V.; Raphael, N.; Narayanan, R.; Lopes, R.; Kondhalkar, D.; Khare, N. K.; Mittra, I.
10.1101/2023.08.07.551233 — immunology — Posted on 2024-08-08
3885 Attenuated processing of vowels in the left hemisphere predicts speech-in-noise perception deficit in children with autism
Fadeev, K. A.; Romero Reyes, I. V.; Goiaeva, D. E.; Obukhova, T. S.; Ovsiannikova, T. M.; Prokofyev, A. O.; Rytikova, A. M.; Novikov, A. Y.; Kozunov, V. V.; Stroganova, T. A.; Orekhova, E. V.
10.1101/2024.06.24.600191 — neuroscience — Posted on 2024-08-08
3889 PbrSYP71 regulates pollen tube growth by maintaining uneven distribution of the ER in Pyrus
Zhang, M.; Tang, C.; Lan, C.; Zhang, N.; Yue, D.; Xie, Z.; Qian, M.; sun, m.; liu, z.; xie, z.; Zhang, H.; Liu, Z.; Zhang, S.; Wang, P.; Wu, J.
10.1101/2024.01.17.576111 — plant biology — Posted on 2024-08-08
3891 A computational model of fractal interface formation in bacterial biofilms
Brooks, C.; Yao, M.; McCool, J. T.; Gillman, A.; Suel, G. M.; Mugler, A.; Larkin, J. W.
10.1101/2022.05.10.491419 — biophysics — Posted on 2024-08-08
3892 Strain-resolved de-novo metagenomic assembly of viral genomes and microbial 16S rRNAs
Jochheim, A.; Jochheim, F. E.; Kolodyazhnaya, A.; Morice, E.; Steinegger, M.; Soeding, J.
10.1101/2024.03.29.587318 — bioinformatics — Posted on 2024-08-08
3893 Genetic estimates and genome-wide association studies of antibody response in Tanzanian dairy cattle
Hernandez-Castro, L. E.; Cook, E. A. J.; Matika, O.; Mengele, I. J.; Motto, S. K.; Bwatota, S. F.; Zirra-Shallangwa, B.; Pong-Wong, R.; Prendergast, J.; Mrode, R.; Toye, P. G.; Komwihangilo, D. M.; Lyatuu, E.; Karani, B. E.; Nangekhe, G.; Mwai, O. A.; Shirima, G. M.; Bronsvoort, B. M. d. C.
10.1101/2024.08.05.606566 — genetics — Posted on 2024-08-08
3894 PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
Liu, F.; Liu, W.; Tan, Y.; Shang, Y.; Ling, S.; Jiang, X.; Zhang, Z.; Sun, S.; Xie, P.
10.1101/2024.08.06.606911 — cell biology — Posted on 2024-08-08
3895 Microdissected tumor cuboids: a microscale cancer model for large-scale testing that retains a complex tumor microenvironment
Horowitz, L. F.; Rodriguez-Mias, R. A.; Chang, M.; Zhu, S.; Gottshall, N. R.; Stepanov, I.; Stiles, C.; Yeung, M.; Nguyen, T. N.; Lockhart, E. J.; Yeung, R. S.; Villen, J.; Gujral, T. S.; Folch, A.
10.1101/2024.03.22.586189 — cancer biology — Posted on 2024-08-08
3897 Canonical and non-canonical PRC1 differentially contribute to the regulation of neural stem cell fate
Hoffmann, J.; Schutze, T. M.; Kolodziejczyk, A.; Krankel, A.; Reinhardt, S.; Derihaci, R. P.; Birdir, C.; Wimberger, P.; Koseki, H.; Albert, M.
10.1101/2024.08.07.606990 — developmental biology — Posted on 2024-08-07
3899 A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology
Zhang, Y.; Leung, A. K.; Kang, J. J.; Sun, Y.; Wu, G.; Li, L.; Sun, J.; Cheng, L.; Qiu, T.; Zhang, J.; Wierbowski, S.; Gupta, S.; Booth, J.; Yu, H.
10.1101/2023.03.06.531441 — systems biology — Posted on 2024-08-08
3904 Targeting oncogenic K-Ras mutants with a small-molecule degrader through Nedd4-1
Zeng, T.; Jiang, T.; Zhang, B.; Zhang, T.; Dai, W.; Yin, X.; Li, Y.; Wu, C.; Wu, Y.; Chi, X.; Deng, X.; Wang, H.-R.
10.1101/2024.04.26.591418 — cancer biology — Posted on 2024-08-07
3905 A STAT3 Degrader Demonstrates Pre-clinical Efficacy in Venetoclax resistant Acute Myeloid Leukemia
Chakraborty, S.; Morganti, C.; Rivera Pena, B.; Zhang, H.; Verma, D.; Zaldana, K.; Gitego, N.; Ma, F.; Aluri, S.; Pradhan, K.; Gordon, S.; Mantzaris, I.; Goldfinger, M.; Feldman, E.; Gritsman, K.; Shi, Y.; Hubner, S.; Qiu, Y. H.; Brown, B. D.; Skwarska, A.; Verma, A.; Konopleva, M.; Tabe, Y.; Gavathiotis, E.; Colla, S.; Gollob, J.; Dey, J.; Kornblau, S. M.; Koralov, S. B.; Ito, K.; Shastri, A.
10.1101/2024.08.05.599788 — cancer biology — Posted on 2024-08-07
3906 MUC2 Expression Modulates Immune Infiltration in Colorectal Cancer
Raynaud, C. M.; Jabeen, A.; Ahmed, E. I.; Hubrack, S.; Sanchez, A.; Sherif, S.; A Al-Shaibi, A.; Roelands, J.; Lo, B.; Bedognetti, D.; Hendrickx, W. R. L.
10.1101/2024.08.06.594842 — cancer biology — Posted on 2024-08-07
3907 A computational model of fractal interface formation in bacterial biofilms
Brooks, C.; Yao, M.; McCool, J. T.; Gillman, A.; Suel, G. M.; Mugler, A.; Larkin, J. W.
10.1101/2022.05.10.491419 — biophysics — Posted on 2024-08-07
3908 LitGene: a transformer-based model that uses contrastive learning to integrate textual information into gene representations
Jararweh, A.; Macaulay, O.; Arredondo, D.; Oyebamiji, O.; Hu, Y.; Tafoya, L.; Zhang, Y.; Virupakshappa, K.; Sahu, A.
10.1101/2024.08.07.606674 — bioinformatics — Posted on 2024-08-07
3912 Discovery and Engineering of a New BvCas12a Nuclease for Mammalian Genome Editing and Nucleic Acid Detection
SHEN, X.; HUANG, L.; WANG, D.; LIU, C.; CHEN, K.; LI, B.; QI, C.; ZOU, Y.; XIAO, L.; JIANG, Y.; LAN, H.; ZHENG, Y.
10.1101/2024.08.07.606956 — genomics — Posted on 2024-08-07
3917 Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage
Anjum, H.; Smith, J. P.; Martini, A. G.; Yacu, G. S.; Medrano, S.; Gomez, R. A.; Sequeira-Lopez, M. L. S.; Quaggin, S. E.; Finer, G.
10.1101/2024.03.25.586641 — developmental biology — Posted on 2024-08-07
3919 p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD
Regnier, M.; Polizzi, A.; Fougeray, T.; Fougerat, A.; Perrier, P.; Anderson, K.; Lippi, Y.; Smati, S.; Lukowicz, C.; Lasserre, F.; Fouche, E.; Huillet, M.; Rives, C.; Tramunt, B.; Naylies, C.; Garcia, G.; Rousseau-Bacquie, E.; Bertrand-Michel, J.; Canlet, C.; Chevolleau-Mege, S.; Debrauwer, L.; Heymes, C.; Burcelin, R.; Levade, T.; Gourdy, P.; Wahli, W.; Blum, Y.; Gamet-Payrastre, L.; Ellero-Simatos, S.; Guillermet-Guibert, J.; Hawkins, P.; Stephens, L.; Montagner, A.; Loiseau, N.; Guillou, H.
10.1101/2024.01.09.574858 — cell biology — Posted on 2024-08-07
3921 Coevolving Residues Distant from the Ligand Binding Site are Involved in GAF Domain Function
Ahmed, W. S.; Geethakumari, A. M.; Sultana, A.; Tiwari, A.; Altamash, T.; Arshad, N.; Visweswariah, S. S.; Biswas, K. H.
10.1101/2024.08.07.605472 — molecular biology — Posted on 2024-08-07
3922 Rapid Raman spectroscopy-based test for antimicrobial resistance
Mushenkov, V.; Zhigalova, K.; Denisov, P.; Gordeev, A.; Lukyanov, D.; Kukushkin, V.; Priputnevich, T.; Zavyalova, E.
10.1101/2024.08.07.606953 — molecular biology — Posted on 2024-08-07
3923 Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
Fry, L. G.; Roys, H.; Bowlin, A. K.; Venugopal, G.; Bird, J. T.; Weaver, A.; Byrum, S. D.; Weinkopff, T.
10.1101/2024.08.07.605632 — microbiology — Posted on 2024-08-07
3924 NEDD4-binding protein 1 suppresses HBV replication by degrading HBV RNAs
Kobayashi, N.; Suzuki, S.; Sakamoto, Y.; Suzuki, R.; Mori, K.; Kosugi, Y.; Liang, L.; Saito, T.; Izumi, T.; Noda, K.; Okuzaki, D.; Kanegae, Y.; Hayashi, S.; Tanaka, Y.; Matsuura, Y.; Takeuchi, O.; Tamura, T.; Taketomi, A.; Fukuhara, T.
10.1101/2023.10.06.561254 — microbiology — Posted on 2024-08-07
3926 Gut microbiome shifts in chronic systolic heart failure are associated with disease severity and clinical improvement
Mamic, P.; Shi, H.; Zhou, W.; Bararpour, N.; Contrepois, K.; Park, H.; Avina, M.; Rose, S. M. S.-F.; Heidenreich, P. A.; Khush, K. K.; Fowler, M. B.; Tang, W. W.; Sallam, K.; Sonnenburg, J. L.; Huang, K. C.; Snyder, M. P.
10.1101/2024.08.06.606872 — microbiology — Posted on 2024-08-07
3928 Migration and standing genetic variation in vaginal and rectal yeast populations in recurrent vulvovaginal candidiasis
Adamu Bukari, A.-R.; Kukurudz-Gorowski, R.; de Graaf, A.; Habon, D.; Manyaz, B.; Syvolos, Y.; Sumanarathnea, A.; Poliquin, V.; Gerstein, A. C.
10.1101/2023.07.19.549743 — microbiology — Posted on 2024-08-07
3932 Pathogenic Th17 cells in ZAP-70 mutant mice share T cell receptor features with Wild-type Tregs
Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.
10.1101/2024.03.01.582868 — immunology — Posted on 2024-08-07
3936 Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex
Bibineyshvili, Y.; Vajtay, T. J.; Salsabilian, S.; Fliss, N.; Suvarnakar, A.; Fang, J.; Teng, S.; Alder, J.; Najafizadeh, L.; Margolis, D. J.
10.1101/2024.04.24.590835 — neuroscience — Posted on 2024-08-07
3940 Enhanced Working Memory Representations for Rare Events
Carrasco, C. D.; Simmons, A. M.; Kiat, J. E.; Luck, S. J.
10.1101/2024.03.20.585952 — neuroscience — Posted on 2024-08-07
3941 A Curated Compendium of Transcriptomic Data for the Exploration of Neocortical Development
Sonthalia, S.; Li, G.; Blanco, X. M.; Casella, A.; Liu, J.; Stein-O'Brien, G.; Caffo, B.; Adkins, S.; Orvis, J.; Hertzano, R.; Mahurkar, A.; Gillis, J. A.; Werner, J.; Ma, S.; Micali, N.; Sestan, N.; Rakic, P.; Baro, G. S.; Ament, S. A.; Colantuoni, C.
10.1101/2024.02.26.581612 — neuroscience — Posted on 2024-08-07
3942 Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body Myositis.
Kleefeld, F.; Cross, E.; Lagos, D.; Schoser, B.; Hentschel, A.; Ruck, T.; Nelke, C. J.; Walli, S.; Hahn, K.; Hathazi, D.; Mammen, A. L.; Casal-Dominguez, M.; Gut, M.; Gut, I.; Heath, S.; Schaenzer, A.; Goebel, H.-H.; Pinal-Fernandez, I.; Roos, A.; Preusse, C.; Stenzel, W.; Horvath, R.
10.1101/2024.08.05.606624 — neuroscience — Posted on 2024-08-07
3943 Sex-specific behavioral and thalamo-accumbal circuit adaptations after oxycodone abstinence.
Alonso-Caraballo, Y.; Li, Y.; Constantino, N. J.; Neal, M. A.; Driscoll, G. S.; Mavrikaki, M.; Bolshakov, V. Y.; Chartoff, E. H.
10.1101/2024.08.01.605459 — neuroscience — Posted on 2024-08-07
3947 Zinc and Metformin Co-Functionalized Polyetheretherketone: A Novel Dental Implant Material Tailored for the Elderly
Liu, Z.; Zhao, E.; Huang, H.; Wu, Y.; He, Y.; Bai, S.; Wang, S.; Fan, S.; Cao, S.; Tang, B.; Wang, Y.
10.1101/2024.08.05.606613 — bioengineering — Posted on 2024-08-07
3948 Dynamic regulation of engineered T7 RNA polymerases by endogenous metabolites
Baumer, Z. T.; Newton, M.; Löfstrand, L.; Carpio Paucar, G. N.; Farny, N. G.; Whitehead, T. A.
10.1101/2024.08.07.607023 — bioengineering — Posted on 2024-08-07
3949 VUStruct: a compute pipeline for high throughput and personalized structural biology
Moth, C. W.; Sheehan, J. H.; Mamun, A. A.; Sivley, R. M.; Gulsevin, A.; Rinker, D.; Capra, J. A.; Meiler, J.
10.1101/2024.08.06.606224 — biochemistry — Posted on 2024-08-07
3951 Extensively acquired antimicrobial resistant bacteria restructure the individual microbial community in post-antibiotic conditions
Baek, J. W.; Lim, S.; Park, N.; Song, B.; Kirtipal, N.; Nielsen, J.; Mardinoglu, A.; Shoaie, S.; Kim, J.-i.; Son, J. W.; Koh, A.; Lee, S.
10.1101/2024.08.07.606955 — genomics — Posted on 2024-08-07
3952 Latent generative modeling of long genetic sequences with GANs
Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Yelmen, B.; Jay, F.
10.1101/2024.08.07.607012 — genomics — Posted on 2024-08-07
3954 Improved vectors for retron-mediated CRISPR-Cas9 genome editing in Saccharomyces cerevisiae
Stuecker, T. N.; Hood, S. E.; Molina Pineda, J.; Lenaduwe, S.; Winter, J.; Sadhu, M. J.; Lewis, J. A.
10.1101/2024.08.06.606807 — genetics — Posted on 2024-08-07
3955 Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans
Krause-Kyora, B.; da Silva, N. A.; Kaplan, E.; Kolbe, D.; Wohlers, I.; Busch, H.; Ellinghaus, D.; Caliebe, A.; Sezgin, E.; Nebel, A.; Schreiber, S.
10.1101/2024.08.06.606840 — evolutionary biology — Posted on 2024-08-07
3956 Global invasion patterns and dynamics of disease vector mosquitoes
Pabst, R.; Sousa, C. A.; Essl, F.; Garcia-Rodriguez, A.; Liu, D.; Lenzner, B.; Schertler, A.; Zezere, J. L.; Capinha, C.
10.1101/2024.08.06.606755 — ecology — Posted on 2024-08-07
3957 Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles
Vendrell-Fernandez, S.; Beamud, B.; Abou-Haydar, Y.; Am de Sousa, J.; Burlaud-Gaillard, J.; Kornobis, E.; Raynal, B.; Vinh, J.; Bikard, D.; Ghigo, J.-M.
10.1101/2024.08.07.606950 — microbiology — Posted on 2024-08-07
3959 AMPK/ULK1 activation downregulates TXNIP, Rab5, and Rab7 and inhibits endocytosis-mediated entry of human pathogenic viruses
Diesendorf, V.; La Rocca, V.; Teutsch, M.; Alattar, H.; Obernolte, H.; Kenst, K.; Seibel, J.; Worsdorfer, P.; Sewald, K.; Steinke, M.; Schneider-Schaulies, S.; Lutz, M. B.; Munschauer, M.; Bodem, J.
10.1101/2024.08.06.606943 — microbiology — Posted on 2024-08-07
3965 Forest dieback in drinking water protection areas - a hidden threat to water quality
Winter, C.; Mueller, S.; Kattenborn, T.; Stahl, K.; Szillat, K.; Weiler, M.; Schnabel, F.
10.1101/2024.08.07.606951 — biochemistry — Posted on 2024-08-07
3966 Scalable imaging-free spatial genomics through computational reconstruction
Hu, C.; Borji, M.; Marrero, G. J.; Kumar, V.; Weir, J. A.; Kammula, S. V.; Macosko, E. Z.; Chen, F.
10.1101/2024.08.05.606465 — genomics — Posted on 2024-08-07
3970 Predicting purification process fit of monoclonal antibodies using machine learning
Maier, A. J.; Cha, M.; Burgess, S.; Wang, A.; Cuellar, C.; Kim, S.; Rajan, N. S.; Neyyan, J.; Sengupta, R.; O'Connor, K.; Ott, N.; Williams, A. J.
10.1101/2024.08.05.606711 — bioinformatics — Posted on 2024-08-07
3977 A single-nucleus census of immune and non-immune cell types for the major immune organ systems of chicken.
Sculley, E. R.; Rice, E. S.; Carroll, R. A.; Driver, J. P.; Smith, J.; Kaufman, J.; Hearn, C.; Balic, A.; Chen, P.; Lamont, S. J.; Kramer, S.; Drechsler, Y.; Cheng, H.; Warren, W. C.
10.1101/2024.08.05.606414 — immunology — Posted on 2024-08-07
3978 CryoEM structure of an MHC-I/TAPBPR peptide bound intermediate reveals the mechanism of antigen proofreading
Sun, Y.; Pumroy, R. A.; Mallik, L.; Chaudhuri, A.; Wang, C.; Hwang, D.; Danon, J.; Dasteh Goli, K.; Moiseenkova-Bell, V.; Sgourakis, N.
10.1101/2024.08.05.606663 — immunology — Posted on 2024-08-07
3979 Desegregation of neuronal predictive processing
Wang, B.; Audette, N. J.; Schneider, D. M.; Aljadeff, J.
10.1101/2024.08.05.606684 — neuroscience — Posted on 2024-08-07
3982 Image retrieval based on closed-loop visual-semantic neural decoding
Fukuma, R.; Yanagisawa, T.; Sugano, H.; Tamura, K.; Oshino, S.; Tani, N.; Iimura, Y.; Khoo, H. M.; Suzuki, H.; Yang, H.; Iwata, T.; Nakajima, M.; Nishimoto, S.; Kamitani, Y.; Kishima, H.
10.1101/2024.08.05.606113 — neuroscience — Posted on 2024-08-07
3987 Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy
Perdikari, A.; Woods, V. A.; Ebrahim, A.; Lawler, K.; Bounds, R.; Singh, N. I.; Mehlman, T.; Riley, B. T.; Sharma, S.; Morris, J. W.; Keogh, J. M.; Henning, E.; Smith, M.; Farooqi, I. S.; Keedy, D. A.
10.1101/2024.08.05.603709 — biophysics — Posted on 2024-08-07
3990 In-silico heart model phantom to validate cardiac strain imaging
Mukherjee, T.; Usman, M.; Mehdi, R. R.; Mendiola, E.; Ohayon, J.; Lindquist, D.; Shah, D.; Sadayappan, S.; Pettigrew, R.; Avazmohammadi, R.
10.1101/2024.08.05.606672 — bioengineering — Posted on 2024-08-07
3992 Quadrant darkfield (QDF) for label-free imaging of intracellular puncta
Moustafa, T. E.; Belote, R. L.; Polanco, E. R.; Judson-Torres, R. L.; Zangle, T. A.
10.1101/2024.08.05.606686 — bioengineering — Posted on 2024-08-07
3995 Using phylogenetic summary statistics for epidemiological inference
Nunez, R. C.; Hart, G. R.; Famulare, M.; Lorton, C.; Herbeck, J. T.
10.1101/2024.08.07.607080 — genetics — Posted on 2024-08-07
3996 Interpretable Solutions for Stochastic Dynamic Programming
Mestres, J. F.; Dietterich, T. G.; Buffet, O.; Chades, I.
10.1101/2024.08.05.606713 — ecology — Posted on 2024-08-07
3997 A transgene-free, human peri-gastrulation embryo model with trilaminar embryonic disc-, amnion- and yolk sac-like structures
Sun, S.; Zheng, Y.; Kim, Y. S.; Zhong, Z.; Kobayashi, N.; Xue, X.; Liu, Y.; Zhou, Z.; Xu, Y.; Zhai, J.; Wang, H.; Fu, J.
10.1101/2024.08.05.606556 — developmental biology — Posted on 2024-08-07
3998 Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop
Willemsen, L.; Lee, J.; Shinde, P.; Soldevila, F.; Aoki, M.; Orfield, S.; Kojima, M.; Antunes, R. d. S.; Sette, A.; Peters, B.
10.1101/2024.08.05.606623 — immunology — Posted on 2024-08-07
3999 Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity
Yu, H.; Nishio, H.; Barbi, J.; Mitchell-Flack, M.; Vignali, P. D. A.; Zheng, Y.; Lebid, A.; Chang, K.-Y.; Fu, J.; Higgins, M.; Huang, C.-T.; Zhang, X.; Li, Z.; Blosser, L.; Tam, A.; Drake, C. G.; Pardoll, D. M.
10.1101/2024.01.31.578284 — immunology — Posted on 2024-08-07
4009 Rare earth elements extraction from Idaho-sourced surface soil by phytomining
Richardson, K.; Mirkouei, A.; Duellman, K.; Aylward, A.; Zirker, D.; Schwarz, E.; Sun, Y.
10.1101/2024.08.05.606409 — plant biology — Posted on 2024-08-07
4010 CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salt stress in quinoa
Kobayashi, Y.; Sugita, R.; Fujita, M.; Yasui, Y.; Murata, Y.; Ogata, T.; Nagatoshi, Y.; Fujita, Y.
10.1101/2024.08.05.606677 — plant biology — Posted on 2024-08-07
4013 Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma
Shema, E.; Griess, O.; Furth, N.; Harpaz, N.; Di Bernardo, N.; Salame, T. M.; Dassa, B.; Karagiannidis, I.; Isshiki, Y.; Gross, M.; Melnick, A. M.; Beguelin, W.; Ron, G.
10.1101/2024.08.05.606629 — cancer biology — Posted on 2024-08-07
4016 Ordering molecular diversity in untargeted metabolomics via molecular community networking
Coler, E. A.; Melnik, A.; Lotfi, A.; Moradi, D.; Ahiadu, B.; Portal Gomes, P. W.; Patan, A.; Dorrestein, P. C.; Barnes, S.; Boginski, V.; Semenov, A.; Aksenov, A. A.
10.1101/2024.08.02.606356 — biochemistry — Posted on 2024-08-07
4018 Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks
Sui, X.; Lo, J. A.; Luo, S.; He, Y.; Tang, Z.; Lin, Z.; Zhou, Y.; Wang, W. X.; Liu, J.; Wang, X.
10.1101/2024.08.05.606553 — genomics — Posted on 2024-08-07
4020 Environmental controls on crenarchaeol distributions in hydrothermal springs
Calhoun, A. N.; Blewett, J.; Colman, D.; Amenabar, M. J.; Harris, C. M.; Boyd, E.; Pearson, A.; Leavitt, W. D.
10.1101/2024.07.09.602736 — microbiology — Posted on 2024-08-07
4021 Mast cell-derived chymases are essential for the resolution of inflammatory pain in mice
de Souza, S.; Laumet, S.; Inyang, K. E.; Hua, H.; Sim, J.; Folger, J. K.; Moeser, A. J.; Laumet, G.
10.1101/2024.08.05.606617 — immunology — Posted on 2024-08-07
4022 High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils
Emmanuelli, A.; Salvagno, C.; Hwang, S.-M.; Awasthi, D.; Sandoval, T. A.; Chae, C.-S.; Cheong, J.-G.; Tan, C.; Iwawaki, T.; Cubillos-Ruiz, J. R.
10.1101/2024.08.05.606646 — immunology — Posted on 2024-08-07
4023 A hidden mark of a troubled past: neuroimaging and transcriptomic analyses reveal interactive effects of maternal immune activation and adolescent THC exposure in the absence of overt behavioural disruptions
Moreno-Fernandez, M.; Lujan, V.; Baliyan, S.; Poza, C.; Capellan, R.; De las Heras, N.; Morcillo, M. A.; Oteo-Vives, M.; Ambrosio, E.; Ucha, M.; Higuera-Matas, A.
10.1101/2024.08.05.606145 — neuroscience — Posted on 2024-08-07
4025 The intersection of endocrine signaling and neuroimmune communication regulates neonatal nociception
Fadaka, A. O.; Dourson, A. J.; Hofmann, M. C.; Gupta, P.; Raut, N. G. R.; Jankowski, M. P.
10.1101/2024.07.26.605393 — neuroscience — Posted on 2024-08-07
4027 Standardising a microbiome pipeline for body fluid identification from complex crime scene stains
Swayambhu, M.; Gysi, M.; Haas, C.; Schuh, L.; Walser, L.; Javanmard, F.; Flury, T.; Ahannach, S.; Lebeer, S.; Hanssen, E. N.; Snipen, L.; Bokulich, N.; Kuemmerli, R.; Arora, N.
10.1101/2024.08.05.604586 — bioinformatics — Posted on 2024-08-07
4028 Extensive Surveillance of Mosquitoes and molecular investigation of Arboviruses in central Iran; First Record of Molecular Identification of Culex tarsalis in Qom Province
Abedi-Astaneh, F.; ABBASI, E.; Raoofi Rad, H.; Hassan Pouriayevali, M.; Jalali, T.; Izanlou, H.; Ebrahimi, M.; Salehi Vaziri, M.; Hamta, A.; HosseinAnliPour, S. A.; Eshaghieh, M.; Ansari Cheshmeh, M.; Talbalaghi, A.
10.1101/2024.08.06.606915 — molecular biology — Posted on 2024-08-07
4031 Biased recruitment of H3.3 by HIRA is dictated by de-/acetylation and determines transcription memory and response
Usha Satheesan, S.; Chakrabarti, S.; Fulzele, A.; Marcellin, M.; Locard-Paulet, M.; Peredo, A. G.-d.; Kolthur-Seetharam, U.
10.1101/2024.08.07.606949 — molecular biology — Posted on 2024-08-07
4032 DROSHA, DICER and Damage-Induced long ncRNA control BMI1-dependent transcriptional repression at DNA double-strand break
Esposito, F.; Capozzo, I.; Modafferi, S.; Gioia, U.; Manfredi, L.; Ianelli, F.; Colantoni, A.; Riccardi, A.; di Lillo, A.; Tavella, S.; Cabrini, M.; d'Adda di Fagagna, F.; Francia, S.
10.1101/2024.08.07.606960 — molecular biology — Posted on 2024-08-07
4034 Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional WFS1 variant
Torchio, S.; Siracusano, G.; Cuozzo, F.; Zamarian, V.; Pellegrini, S.; Manenti, F.; Bonfanti, R.; Frontino, G.; Sordi, V.; Chimienti, R.; Piemonti, L.
10.1101/2024.08.06.606801 — cell biology — Posted on 2024-08-07
4037 On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa
Benz, C.; Raas, M. W. D.; Tripathi, P.; Faktorova, D.; Tromer, E. C.; Akiyoshi, B.; Lukes, J.
10.1101/2024.08.06.606595 — cell biology — Posted on 2024-08-07
4038 βA3/A1-crystallin is an epigenetic regulator of histone deacetylase 3 (HDAC3) in the retinal pigmented epithelial (RPE) cells
Chatterjee, S.; Ghosh, S.; Sin, Z.; Davis, E.; Preval, L. V.; Tran, N.; Bammidi, S.; Gautam, P.; Hose, S.; Sergeev, Y.; Flores-Bellver, M.; Al Diri, I.; Sinha, D.; Guha, P.
10.1101/2024.08.06.606634 — cell biology — Posted on 2024-08-07
4039 PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
Liu, F.; Liu, W.; Tan, Y.; Shang, Y.; Ling, S.; Jiang, X.; Zhang, Z.; Sun, S.; Xie, P.
10.1101/2024.08.06.606911 — cell biology — Posted on 2024-08-07
4040 Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners
Coate, K. C.; Dai, C.; Singh, A. K.; Stanley, J. E.; Covington, B. A.; Bradley, A.; Oladipupo, F. O.; Gong, Y.; Wisniewski, S.; Spears, E. A.; Poffenberger, G.; Bustabad, A.; Rodgers, T. J.; Dey, N.; Schultz, L. D.; Greiner, D. L.; Yan, H.; Powers, A. C.; Chen, W.; Dean, E. D.
10.1101/2024.08.06.606926 — cell biology — Posted on 2024-08-07
4041 Episodic Transport of Protein Aggregates Achieves a Positive Size Selectivity in Aggresome Formation
Fang, R.; Bai, L.; Li, B.; Dong, K.; Paulo, J. A.; Zhou, M.; Chu, Y.-C.; Song, Y.; Sherman, M. Y.; Gygi, S.; Field, C.; Mitchison, T.; Lu, Y.
10.1101/2024.08.06.606767 — cell biology — Posted on 2024-08-07
4043 Neural circuit mechanisms for steering control in walking Drosophila
Rayshubskiy, A.; Holtz, S. L.; Bates, A.; Vanderbeck, Q. X.; Capdevila, L. S.; Wilson, R. I.
10.1101/2020.04.04.024703 — neuroscience — Posted on 2024-08-07
4046 Formation of brain-wide neural geometry during visual item recognition in monkeys
Chen, H.; Kunimatsu, J.; Oya, T.; Imaizumi, Y.; Hori, Y.; Matsumoto, M.; Tsubo, Y.; Hikosaka, O.; Minamimoto, T.; Naya, Y.; Yamada, H.
10.1101/2024.08.05.604527 — neuroscience — Posted on 2024-08-07
4048 Learning in single cells: biochemically-plausible models of habituation
Eckert, L.; Vidal, M. S.; Zhao, Z.; Garcia-Ojalvo, J.; Martinez-Corral, R.; Gunawardena, J.
10.1101/2024.08.04.606534 — systems biology — Posted on 2024-08-07
4049 Discovery of the first-efficacious A2AR negative allosteric modulators for high adenosine cancer immunotherapies
Boujut, M.; Heritier, M.; Gouiller, A.; Suess, C.; Scapozza, A.; De Smedt, T.; Guibert, M.; Tardy, S.; Hamed, H.; Pejoski, D.; Scapozza, L.
10.1101/2024.08.05.606339 — pharmacology and toxicology — Posted on 2024-08-07
4052 Pertpy: an end-to-end framework for perturbation analysis
Heumos, L.; Ji, Y.; May, L.; Green, T.; Zhang, X.; Wu, X.; Ostner, J.; Peidli, S.; Schumacher, A.; Hrovatin, K.; Mueller, M.; Chong, F.; Sturm, G.; Tejada, A.; Dann, E.; Dong, M.; Bahrami, M.; Gold, I.; Rybakov, S.; Namsaraeva, A.; Moinfar, A. A.; Zheng, Z.; Roellin, E.; Mekki, I.; Sander, C.; Lotfollahi, M.; Schiller, H. B.; Theis, F. J.
10.1101/2024.08.04.606516 — bioinformatics — Posted on 2024-08-07
4053 Get to know your neighbors with a SNAQ™: A framework for single cell spatial neighborhood analysis in immunohistochemical images
Silver, A.; Chakraborty, A.; Pittu, A.; Feier, D.; Anica, M.; West, I.; Sarkisian, M. R.; Deleyrolle, L. P.
10.1101/2024.08.04.606539 — bioinformatics — Posted on 2024-08-07
4056 GOLEM: A tool for visualizing the distribution of Gene regulatOry eLEMents within the plant promoters with a focus on male gametophyte
Nevosad, L.; Klodova, B.; Racek, T.; Prerovska, T.; Kusova, A.; Svobodova, R.; Honys, D.; Prochazkova Schrumpfova, P.
10.1101/2024.08.05.606583 — bioinformatics — Posted on 2024-08-07
4059 Transocular detection of premotor Parkinson's disease via retinal neurovascular coupling through functional OCT angiography
Liu, K.; Wang, R.; Huang, L.; Zhang, H.; Gao, M.; Sun, B.; Tan, Y.; Ye, J.; Ding, Z.; Gu, Y.; Zhang, S.; Li, P.
10.1101/2024.08.04.606502 — bioengineering — Posted on 2024-08-07
4063 Blood host preferences and competitive inter-species dynamics within an African malaria vector species complex inferred from signs of animal activity around aquatic larval habitats.
Walsh, K. A.; Kavishe, D. R.; Duggan, L. M.; Tarimo, L. J.; Msoffe, R. V.; Manase, E.; Govella, N. J.; Eichhorn, M. P.; Kaindoa, E. W.; Butler, F.; Killeen, G. F.
10.1101/2024.08.04.606513 — ecology — Posted on 2024-08-07
4065 Connectivity loss in experimental pond networks leads to biodiversity loss in microbial communities
Szabo, B.; Vaczy-Foldi, M.; Vad, C. F.; Palffy, K.; Huynh, T.-H.; Dobosy, P.; Fierpasz, A.; Marton, Z.; Felfoldi, T.; Horvath, Z.
10.1101/2024.08.05.606584 — ecology — Posted on 2024-08-07
4066 Novel replication-competent reporter-expressing Rift Valley fever viruses for molecular studies
Nogales, A.; Alonso, C.; Moreno, S.; Lorenzo, G.; Borrego, B.; Martinez-Sobrido, L.; Brun, A.
10.1101/2024.08.06.606778 — microbiology — Posted on 2024-08-07
4067 Borrelia burgdorferi BB0346 is an Essential, Structurally Variant LolA Homolog that is Primarily Required for Homeostatic Localization of Periplasmic Lipoproteins
Murphy, B. T.; Wiepen, J. J.; Graham, D. E.; Swanson, S.; Kashipathy, M. M.; Cooper, A.; Battaile, K. P.; Johnson, D. K.; Florens, L.; Blevins, J. S.; Lovell, S.; Zückert, W. R.
10.1101/2024.08.06.606844 — microbiology — Posted on 2024-08-07
4068 Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy
Pereira, P.; Panier, J.; Nater, M.; Herbst, M.; Calvanese, A. L.; Koksal, H.; Castanon, H.; Cecconi, V.; Tallon de Lara, P.; Pascolo, S.; van den Broek, M.
10.1101/2024.08.05.606588 — immunology — Posted on 2024-08-07
4069 A Small Interfering Peptide Potentiates AMPA Receptor Diffusional Trapping and Prevents Social-Isolation-Induced Forgetting of Fear Memory
Gundersen, J. E. T.; Wu, X.; Song, J.; Yao, J.; Nesbo, H. H.; Pokharna, A.; Mergiya, T. F.; Liu, H.; Sun, S.; Greger, I.; Wang, C.; Xu, N.-j.; Bramham, C. R.; Zhang, H.
10.1101/2024.08.04.606518 — neuroscience — Posted on 2024-08-07
4072 GBA1 MUTATIONS ALTER THE PHENOTYPE AND BEHAVIOUR OF DOPAMINERGIC NEURONS IN PARKINSON DISEASE, INFLUENCING VGLUT2 AND CRYAB EXPRESSION
Rodriguez-Traver, E.; Suarez, L. M.; Crespo, C.; Gonzalez-Burgos, I.; Vecino, R.; Jurado-Coronel, J. C.; Galan, M.; Gonzalez-Gonzalez, M.; Moratalla, R.; Vicario, C.
10.1101/2024.08.05.606574 — neuroscience — Posted on 2024-08-07
4073 Delineating In-Vivo T1-Weighted Intensity Profiles Within the Human Insula Cortex Using 7-Tesla MRI
Dalby, C.; Dibble, A. J.; Carvalheiro, J.; Queirazza, F.; Sevegnani, M.; Harvey, M.; Svanera, M.; Fracasso, A.
10.1101/2024.08.05.605123 — neuroscience — Posted on 2024-08-07
4075 Circular RNAs exhibit exceptional stability in the aging brain and serve as reliable age and experience indicators
Kirio, K.; Patop, I. L.; Martin Anduaga, A.; Harris, J.; Pamudurti, N.; Martel, C.; Kadener, S.
10.1101/2024.08.04.606529 — neuroscience — Posted on 2024-08-07
4076 What works to improve species conservation state? An analysis of species whose state has improved and the actions responsible
Simkins, A. T.; Sutherland, W. J.; Dicks, L. V.; Hilton-Taylor, C.; Grace, M. K.; Butchart, S. H. M.; Senior, R. A.; Petrovan, S. O.
10.1101/2024.08.04.606320 — zoology — Posted on 2024-08-07
4081 Prenatal Dexamethasone Programs Autonomic Dysregulation in Female Rats
Madhavpeddi, L.; Martinez, M.; Alvarez, J.; Sharma, A.; Hu, C.; Tobet, S. A.; Hale, T. M.
10.1101/2024.08.05.606452 — physiology — Posted on 2024-08-07
4083 Attenuation of Atherosclerosis with PAR4 Deficiency: Differential Platelet Outcomes in apoE-/- vs. Ldlr-/- Mice
Wadding-Lee, C.; Jay, M.; Shearer, S. M.; Benson, T.; Spuzzillo, A.; Howatt, D. A.; Thompson, J.; Daugherty, A.; Mackman, N.; Owens, A. P.
10.1101/2024.08.01.606266 — pathology — Posted on 2024-08-07
4086 Massively parallel quantification of substrate turnover defines protease subsite cooperativity
Gudipati, R. K.; Gaidatzis, D.; Seebacher, J.; Muehlhaeusser, S.; Kempf, G.; Cavadini, S.; Hess, D.; Soneson, C.; Grosshans, H.
10.1101/2023.11.17.567387 — biochemistry — Posted on 2024-08-07
4090 From insect endosymbiont to phloem colonizer: comparative genomics unveils the lifestyle transition of phytopathogenic Arsenophonus strains
Mahillon, M.; Debonneville, C.; Groux, R.; Roquis, D.; Brodard, J.; Faoro, F.; Foissac, X.; Schumpp, O.; Dittmer, J.
10.1101/2024.08.06.606843 — microbiology — Posted on 2024-08-07
4091 GBP2 engages Galectin-9 for immunity against Toxoplasma gondii
Kravets, E.; Poschmann, G.; Haensch, S.; Raba, V.; Weidtkamp-Peters, S.; Degrandi, D.; Stuehler, K.; Pfeffer, K.
10.1101/2021.12.28.474342 — immunology — Posted on 2024-08-07
4092 Pathophysiological response in experimental trauma-related acute kidney injury
Halbgebauer, R.; Schult, L.; Borgel, O.; Maes, A.; Weisshaupt, F.; Rastner, C.; Ast, A.; Lupu, L.; Palmer, A.; Wachter, U.; Schmidt, S. A.; Boor, P.; Rösler, R.; Wiese, S.; Kerckhofs, G.; Huber-Lang, M.
10.1101/2024.08.02.606294 — pathology — Posted on 2024-08-07
4093 Dual-Targeted Microbubbles Promote Apoptosis of M1 Macrophages by Inhibiting Telomerase Activity for Atherosclerosis Therapy
Liu, Y.; Zeng, W.; Huang, Z.; Huang, Y.; Xiong, K.; Sheng, Y.; Lin, X.; Zhong, X.; Ye, J.; Guo, Y.; Arkin, G.; Xu, J.; Fei, H.
10.1101/2024.08.01.606265 — bioengineering — Posted on 2024-08-07
4096 Caliban: Accurate cell tracking and lineage construction in live-cell imaging experiments with deep learning
Schwartz, M.; Moen, E.; Miller, G.; Dougherty, T.; Borba, E.; Ding, R.; Graf, W.; Pao, E.; Van Valen, D. A.
10.1101/803205 — bioinformatics — Posted on 2024-08-07
4098 Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer
Kim, W.; Mirdita, M.; Karin, E. L.; Gilchrist, C. L. M.; Schweke, H.; Soeding, J.; Levy, E.; Steinegger, M.
10.1101/2024.04.14.589414 — bioinformatics — Posted on 2024-08-07
4099 A WFS1 variant disrupting acceptor splice site uncovers the impact of alternative splicing on β cell apoptosis in a patient with Wolfram syndrome.
Chimienti, R.; Torchio, S.; Siracusano, G.; Zamarian, V.; Monaco, L.; Lombardo, M. T.; Pellegrini, S.; Manenti, F.; Cuozzo, F.; Rossi, G.; Carrera, P.; Sordi, V.; Broccoli, V.; Bonfanti, R.; Casari, G.; Frontino, G.; Piemonti, L.
10.1101/2023.12.29.573188 — genetics — Posted on 2024-08-07
4100 An Information Theory Framework for Movement Path Segmentation and Analysis
Sethi, V.; Spiegel, O.; Salter, R.; Cain, S.; Toledo, S.; Getz, W.
10.1101/2024.08.02.606194 — ecology — Posted on 2024-08-07
4104 Wildlife as a sentinel for pathogen introduction in nonendemic areas: first detection of Leishmania tropica in wildlife in Spain
Azami-Conesa, I.; Matas Mendez, P.; Perez-Moreno, P.; Carrion, J.; Alunda, J. M.; Mateo Barrientos, M.; Gomez_Munoz, M. T.
10.1101/2024.03.16.585353 — microbiology — Posted on 2024-08-07
4105 SICKO: Systematic Imaging of Caenorhabtidis Killing Organisms
Espejo, L. S.; Freitas, S.; Silbar, V.; Chang, L.; Balsa, J.; Antenor, A.; Dang, H.; DeNicola, D.; Sutphin, G. L.
10.1101/2023.02.17.529009 — immunology — Posted on 2024-08-07
4106 Helminth-derived metabolites induce tolerogenic functional, metabolic, and transcriptional signatures in dendritic cells that attenuate experimental colitis
Malacco, N. L.; Michi, A. N.; Siciliani, E.; Madrigal, A. G.; Sternlieb, T.; Fontes, G.; King, I. L.; Cestari, I.; Jardim, A.; Stevenson, M. M.; Lopes, F.
10.1101/2023.01.26.525718 — immunology — Posted on 2024-08-07
4107 Synaptogyrin-3 Prevents Cocaine Addiction and Dopamine Deficits
Peck, E. G.; Holleran, K. M.; Curry, A. M.; Holter, K. M.; Estave, P.; Sens, J. P.; Locke, J.; Ortelli, O.; George, B.; Dawes, M.; West, A. M.; Alexander, N.; Kiraly, D. D.; Farris, S.; Gould, R. W.; McCool, B.; Jones, S. R.
10.1101/2024.07.27.605436 — neuroscience — Posted on 2024-08-07
4108 Synaptic Potentiation of Engram cells is Necessary and Sufficient for Context Fear Memory
Cardozo, L. M.; Sousa, A. F.; Dillingham, B. C.; Dang, W.; Job, N.; Yoo, E. J.; Ranamukhaarachchi, S. K.; Yuan, Q.; Mayford, M.
10.1101/2022.01.09.475530 — neuroscience — Posted on 2024-08-07
4111 Clonal evolutionary analysis reveals patterns of malignant transformation in pancreatic cancer from Intraductal Papillary Mucinous IPMN Neoplasms (IPMN)
Pea, A.; He, X.; Upstill-Goddard, R.; Luchini, C.; Santana, L. P. S.; Dreyer, S.; Jamieson, N.; Duthie, F.; MacKay, C.; Dickson, E.; Pulvirenti, A.; Rebus, S.; Genomics Innovation Alliance, ; Scottish Genome Partnership, ; Piccoli, P.; Sperandio, N.; Lawlor, R.; Milella, M.; Froeling, F.; Salvia, R.; Scarpa, A.; Bainkin, A.; Wedge, D.; Chang, D.
10.1101/2024.08.02.606217 — cancer biology — Posted on 2024-08-07
4112 Shape dynamics and migration of branched cells on complex networks
Liu, J.; Boix-Campos, J.; Ron, J. E.; Kux, J. M.; Oremek, M. E. M.; Rossi, A. G.; Gov, N.; Saez, P. J.
10.1101/2024.03.29.585638 — biophysics — Posted on 2024-08-07
4118 An enhanced Eco1 retron editor enables precision genome engineering in human cells from a single-copy integrated lentivirus
Cattle, M. A.; Aguado, L. C.; Sze, S.; Wang, D. Y.; Papagiannakopoulos, T.; Smith, S.; Rice, C. M.; Schneider, W. M.; Poirier, J. T.
10.1101/2024.08.05.606586 — molecular biology — Posted on 2024-08-07
4120 Homeostasis of cytoplasmic crowding by cell wall fluidization and ribosomal counterions
Mukherjee, A.; Huang, Y.; Oh, S.; Sanchez, C.; Chang, Y.-F.; Liu, X.; Bradshaw, G. A.; Benites, N. C.; Paulsson, J.; Kirschner, M. W.; Sung, Y.; Elgeti, J.; Basan, M.
10.1101/2023.08.31.555748 — microbiology — Posted on 2024-08-07
4122 Molecular and cellular rhythms in excitatory and inhibitory neurons in the mouse prefrontal cortex
Burns, J. N.; Jenkins, A. K.; Yin, R.; Zong, W.; Vadnie, C. A.; DePoy, L.; Petersen, K. A.; Tsyglakova, M.; Scott, M. R.; Tseng, G.; Huang, Y. H.; McClung, C. A.
10.1101/2024.07.05.601880 — neuroscience — Posted on 2024-08-07
4124 Guanylate cyclase activity of TIR1/AFB auxin receptorsin rapid auxin responses
Qi, L.; Kwiatkowski, M.; Kulich, I.; Chen, H.; Gao, Y.; Yun, P.; Li, L.; Shabala, S.; Farmer, E.; Jaworski, K.; Friml, J.
10.1101/2023.11.18.567481 — plant biology — Posted on 2024-08-07
4125 Astrocyte extracellular matrix modulate neuronal dendritic development
Hashimoto, J. G.; Margolies, N.; Zhang, X.; Karpf, J.; Song, Y.; Davis, B. A.; Zhang, F.; Linhardt, R. J.; Carbone, L.; Guizzetti, M.
10.1101/2024.08.06.606424 — neuroscience — Posted on 2024-08-06
4132 Autophagosomes coordinate an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling
Segura-Roman, A.; Citron, Y. R.; Shin, M.; Sindoni, N.; Maya-Romero, A.; Rapp, S.; Goul, C. S.; Mancias, J. D.; Zoncu, R.
10.1101/2024.08.06.606738 — cell biology — Posted on 2024-08-06
4133 Temporally restricted activities of En1 regulatory elements underlie distinct limb malformations
Ringel, A. R.; Magg, A.; Benetti, N.; Schoepflin, R.; Kuehnlein, M. N.; Stiege, A. C.; Fischer, U.; Wittler, L.; Lorenz, S.; Mundlos, S.; Allou, L.
10.1101/2024.08.06.606766 — developmental biology — Posted on 2024-08-06
4136 Locating the Missing Chlorophylls f in Far-red Photosystem I
Consoli, G.; Tufail, F.; Leong, H. F.; Viola, S.; Davis, G. A.; Medranda, D.; Rew, N.; Hofer, M.; Simpson, P.; Sandrin, M.; Chachuat, B.; Nelson, J.; Renger, T.; Murray, J. W.; Fantuzzi, A.; Rutherford, A. W.
10.1101/2024.08.06.606606 — biochemistry — Posted on 2024-08-06
4137 Defining short linear motif binding determinants by phage-based multiplexed deep mutational scanning
Benz, C.; Maasen, L.; Simonetti, L.; Mihalic, F.; Lindqvist, R.; Tsitsa, I.; Jemth, P.; Overby, A. K.; Davey, N. E.; Ivarsson, Y.
10.1101/2024.08.06.606761 — biochemistry — Posted on 2024-08-06
4138 The potential of regulatory variant prediction AI models to improve cattle traits
Zhao, R.; Owen, R.; Marr, M.; Jayaraman, S.; Chue Hong, N.; Talenti, A.; Hassan, M. A.; Prendergast, J.
10.1101/2024.08.01.606140 — genomics — Posted on 2024-08-06
4144 ThermoTargetMiner as a proteome integral solubility alteration target database for prospective drugs against lung cancer
Lyu, H.; Gharibi, H.; Sokolova, B.; Voiland, A.; Nilsson, B.; Meng, Z.; Gaetani, M.; Saei, A. A.; Zubarev, R.
10.1101/2024.08.06.606599 — biochemistry — Posted on 2024-08-06
4147 A humanized yeast model for studying TRAPP complex mutations; proof-of-concept using variants from an individual with a TRAPPC1-associated neurodevelopmental syndrome
Zykaj, E.; Abboud, C.; Asadi, P.; Warsame, S.; Greco, B.; Lopez-Sanchez, M.; Bratkovic, D.; Kachroo, A.; Perez-Jurado, L. A.; Sacher, M.
10.1101/2024.08.04.605925 — genetics — Posted on 2024-08-06
4153 RIPK4 driven by TP53 mutations promotes resistance to redox stress of CRC by phosphorylating MTHFD1
Yu, L.; Zhou, S.; Xu, Y.; Zhang, Z.; Cheng, X.; Zhou, C.; Li, W.; He, J.; Ou, Q.; Qin, J.; Fang, Y.-J.; Peng, J.; Lin, J.-Z.; Lin, B.; Hou, Z.; Pan, Z.
10.1101/2024.08.06.606759 — molecular biology — Posted on 2024-08-06
4158 Monosaccharides Drive Salmonella Gut Colonization in a Context-Dependent Manner
Schubert, C.; Nguyen, B. D.; Sichert, A.; Naepflin, N.; Sintsova, A.; Feer, L.; Naef, J.; Daniel, B. B. J.; Steiger, Y.; von Mering, C.; Sauer, U.; Hardt, W.-D.
10.1101/2024.08.06.606610 — microbiology — Posted on 2024-08-06
4159 A vaccine antigen central in influenza A(H5) virus antigenic space confers subtype-wide immunity
Kok, A.; Wilks, S. H.; Tureli, S.; James, S. L.; Bestebroer, T. M.; Burke, D. F.; Funk, M.; van der Vliet, S.; Spronken, M. I.; Rijnink, W. F.; Pattinson, D. J.; de Meulder, D.; Rosu, M. E.; Lexmond, P.; van den Brand, J. M. A.; Herfst, S.; Smith, D. J.; Fouchier, R. A. M.; Richard, M.
10.1101/2024.08.06.606696 — microbiology — Posted on 2024-08-06
4162 Nutrient competition predicts gut microbiome restructuring under drug perturbations
Shi, H.; Newton, D. P.; Nguyen, T. H.; Estrela, S.; Sanchez, J.; Tu, M.; Ho, P.-Y.; Zeng, Q.; DeFelice, B.; Sonnenburg, J. L.; Huang, K. C.
10.1101/2024.08.06.606863 — microbiology — Posted on 2024-08-06
4163 Drug-controlled CAR-T cells through the regulation of cell-cell interactions
Scheller, L.; Attianese, G. M. P. G.; Castellanos-Rueda, R.; Di Roberto, R. B.; Barden, M.; Riboulet, M.; Shui, S.; Cribioli, E.; Marchand, A.; Georgeon, S.; Abken, H.; Reddy, S.; Correia, B.; Irving, M.
10.1101/2024.08.06.606454 — synthetic biology — Posted on 2024-08-06
4165 A COVID-19 Rapid Antigen Test Employing Upconversion Nanoparticles
Zhang, L.; Zhou, J.; Shimoni, O.; Wen, S.; Alghalayini, A.; Liu, Y.; Rezaeishahmirzadi, M.; Liao, J.; Maddahfar, M.; Hunt, R.; Black, M.; Johansen, M. D.; Hansbro, P. M.; Zhang, L.; Stenzel, M.; Warkiani, M. E.; Valenzuela, S. M.; Jin, D.
10.1101/2024.08.05.606725 — bioengineering — Posted on 2024-08-06
4167 Evolution and Diversification of the Aposematic Poison Frog, Oophaga pumilio, in Bocas del Toro
Aguilar-Gomez, D.; Freeborn, L.; Yuan, L.; Smith, L. L.; Guzman, A.; Vaughn, A.; Steigerwald, E.; Stuckert, A.; Yang, Y.; Linderoth, T. P.; MacManes, M.; Richards-Zawacki, C. L.; Nielsen, R.
10.1101/2024.08.02.606438 — evolutionary biology — Posted on 2024-08-06
4168 Human Vascularized Macrophage-Islet Organoids to Model Immune-Mediated Pancreatic β cell Pyroptosis upon Viral Infection
Yang, L.; Han, Y.; Zhang, T.; Dong, X.; Ge, J.; Roy, A.; Zhu, J.; Lu, T.; Vandana, J. J.; de Silva, N.; Robertson, C. C.; Xiang, J. Z.; Pan, C.; Sun, Y.; Que, J.; Evans, T.; Liu, C.; Wang, W.; Naji, A.; Parker, S. C. J.; Schwartz, R. E.; Chen, S.
10.1101/2024.08.05.606734 — developmental biology — Posted on 2024-08-06
4169 On the same side: The immune regulatory protein Vista and its ligands interact in cis
Smorodinsky-Atias, K.; Wiseglass, G.; Salem, M.; Kashani, M.; Boni, N.; Artyukhova, A.; Levy, R.; Rubinstein, R.
10.1101/2024.08.02.606340 — immunology — Posted on 2024-08-06
4172 3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure
Kiemen, A. L.; Almagro Perez, C.; Matos Romero, V.; Forjaz, A.; Braxton, A. M.; Dequiedt, L.; Parksong, J.; Cannon, C. D.; Yuan, X.; Shin, S. M.; Mahesh Babu, J.; Thompson, E. D.; Cornish, T. C.; Ho, W. J.; Wood, L. D.; Wu, P.; Munoz-Barrutia, A.; Hruban, R. H.; Wirtz, D.
10.1101/2024.08.03.606493 — cancer biology — Posted on 2024-08-06
4178 The splicing modulator CLK1 is a candidate oncogenic dependency in pediatric high-grade gliomas
Naqvi, A. S.; Corbett, R. J.; Seghal, P.; Conkrite, K. L.; Rathi, K. S.; Ennis, B. M.; Hayer, K. E.; Zhang, B.; Brown, M. A.; Miller, D. P.; Kraya, A.; Dybas, J. M.; Geng, Z.; Blackden, C.; Arif, S.; Chroni, A.; Lahiri, A.; Hollawell, M. L.; Storm, P. B.; Foster, J. B.; Koptyra, M.; Madsen, P. J.; Diskin, S. J.; Thomas-Tikhonenko, A.; Resnick, A. C.; Rokita, J. L.
10.1101/2024.08.03.606419 — genomics — Posted on 2024-08-06
4179 Probabilistic classification of gene-by-treatment interactions on molecular count phenotypes
Harigaya, Y.; Matoba, N.; Le, B. D.; Valone, J. M.; Stein, J. L.; Love, M. I.; Valdar, W. I.
10.1101/2024.08.03.605142 — genetics — Posted on 2024-08-06
4180 Reduced function of the adaptor SH2B3 promotes T1D via altered γc cytokine-regulated, T cell intrinsic immune tolerance
Watson, T. K.; Rosen, A. B.; Drow, T.; Medjo, J. A.; MacQuivey, M. A.; Ge, Y.; Liggitt, H. D.; Grosvenor, D. A.; Dill-McFarland, K. A.; Altman, M. C.; Concannon, P. J.; Buckner, J. H.; Rawlings, D. J.; Allenspach, E. J.
10.1101/2024.08.02.606362 — immunology — Posted on 2024-08-06
4181 PD-1 controls differentiation, survival, and TCR affinity evolution of stem-like CD8+ T cells
Hor, J. L.; Schrom, E. C.; Wong-Rolle, A.; Vistain, L.; Shang, W.; Dong, Q.; Zhao, C.; Jin, C.; Germain, R. N.
10.1101/2024.08.02.606241 — immunology — Posted on 2024-08-06
4183 TAM receptors mediate the Fpr2-driven pain resolution and fibrinolysis after nerve injury
Hartmannsberger, B.; Ben-Kraiem, A.; Kramer, S.; Guidolin, C.; Kazerani, I.; Doppler, K.; Thomas, D.; Gurke, R.; Sisignano, M.; Kalelkar, P. P.; Garcia, A.; Monje, P. V.; Nusrat, A.; Brack, A.; Krug, S. M.; Sommer, C.; Rittner, H.
10.1101/2024.08.04.605987 — neuroscience — Posted on 2024-08-06
4185 Computational modeling of drug response identifies mutant-specific constraints for dosing panRAF and MEK inhibitors in melanoma
Goetz, A.; Shanahan, F.; Brooks, L.; Lin, E.; Mroue, R.; Dela Cruz, D.; Hunsaker, T.; Czech, B.; Dixit, P.; Segal, U.; Martin, S.; Foster, S. A.; Gerosa, L.
10.1101/2024.08.02.606432 — systems biology — Posted on 2024-08-06
4186 S2-PepAnalyst: A Web Tool for Predicting Plant Small Signalling Peptides
Vomo Donfack, K. L.; Abaach, M.; Luna, A. M.; Ginot, G.; Doblas, V. G.; Morilla, I.
10.1101/2024.08.02.606319 — plant biology — Posted on 2024-08-06
4187 Paradoxical SERCA dysregulation contributes to atrial fibrillation in a model of diet-induced obesity
Ponce-Balbuena, D.; Tyrrell, D.; Cruz-Cortes, C.; Guerrero-Serna, G.; Monteiro da Rocha, A.; Herron, T. J.; Song, J.; Raza, D.; Anumonwo, J.; Goldstein, D.; Espinoza-Fonseca, L. M.
10.1101/2024.08.02.606385 — physiology — Posted on 2024-08-06
4190 Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis
Ozaki, M. K.; Zhang, Y.; Bartlett, A. Q.; De Wilde, E.; Guan, X.; Yang, A.; Xia, Z. K.; Schedin, P. J.
10.1101/2024.08.02.606434 — cancer biology — Posted on 2024-08-06
4191 Genomic evolution of pancreatic cancer at single-cell resolution
Zhang, H.; Sashittal, P.; Karnoub, E.-R.; Jakatdar, A.; Umeda, S.; Hong, J.; Noronha, A. M.; Cardenas, A.; Erakky, A.; McIntyre, C. A.; Hayashi, A.; Lecomte, N.; Park, W.; Pan, N.; O'Reilly, E. M.; Wei, A. C.; Raphael, B. J.; Iacobuzio-Donahue, C. A.
10.1101/2024.08.03.605165 — cancer biology — Posted on 2024-08-06
4192 OXPHOS TARGETING OF MYCN-AMPLIFIED NEUROBLASTOMA
Epp, S. C.; Egan, D.; Poon, E.; Abdul Aziz, A. A.; Wynne, K.; Halasz, M.; Kolch, W.
10.1101/2024.08.03.606365 — cancer biology — Posted on 2024-08-06
4194 Comprehensive Guide of Epigenetics and Transcriptomics Data Quality Control
Comendul, A.; Ruf-zamojski, F.; Ford, C. T.; Agarwal, P.; Zaslavsky, E.; Nudleman, G.; Hariharan, M.; Rubenstein, A.; Nair, V. D.; Pincas, H.; Michaleas, A. M.; Sealfon, S. C.; Woods, C. W.; Claypool, K. T.; Jaimes, R.
10.1101/2024.08.02.606411 — bioinformatics — Posted on 2024-08-06
4198 Localized in vivo prodrug activation using radionuclides
Quintana, J.; Jiang, F.; Kang, M.; Valladolid Onecha, V.; Konik, A.; Qin, L.; Rodriguez, V.; Hu, H.; Borges, N.; Khurana, I.; Banla, L. I.; Le Fur, M.; Caravan, P.; Schuemann, J.; Bertolet, A.; Weissleder, R.; Miller, M.; Ng, T.
10.1101/2024.08.02.606075 — bioengineering — Posted on 2024-08-06
4199 A Tough Biointerface in Human Knee Empowered by Dynamic Phase-transforming Minerals in Collagenous Matrix
Li, W.; Wang, X.; Mao, R.; Li, D.; Meng, H.; Zhang, R.; Fang, J.; Kang, Z.; Wu, B.; Ma, W.; Yao, X.; Xie, C.; Li, R.; Wang, J.; Chen, X.; Pan, X.; Chen, W.; Duan, W.; Gao, H.; Ouyang, H.
10.1101/2024.08.03.606023 — bioengineering — Posted on 2024-08-06
4200 Fallow deer approaching humans are also more likely to be seropositive for Toxoplasma gondii.
Ryan, A. R.; Zintl, A.; Griffin, L. L.; Quinn, M.; Haigh, A.; Sabbatini, P.; Amin, B.; Ciuti, S.
10.1101/2024.08.03.606274 — animal behavior and cognition — Posted on 2024-08-06
4201 Two distinct chromatin modules regulate proinflammatory gene expression
Seufert, I.; Gerosa, I.; Varamogianni-Mamatsi, V.; Vladimirova, A.; Sen, E.; Mantz, S.; Rademacher, A.; Schumacher, S.; Liakopoulos, P.; Kolovos, P.; Anders, S.; Mallm, J.-P.; Papantonis, A.; Rippe, K.
10.1101/2024.08.03.606159 — genomics — Posted on 2024-08-06
4202 High-throughput gene expression analysis with TempO-LINC sensitively resolves complex brain, lung and kidney heterogeneity at single-cell resolution
Eastburn, D. J.; White, K. S.; Jayne, N. D.; Camiolo, S.; Montis, G.; Ha, S.; Watson, K. G.; Yeakley, J. M.; McComb, J.; Seligmann, B.
10.1101/2024.08.03.606484 — genomics — Posted on 2024-08-06
4204 Movement responses to lethal risk: an integrative analysis of proactive and reactive antipredator behaviours in a large herbivore
Vanderlocht, C.; Robira, B.; Corradini, A.; Dal Farra, S.; Ossi, F.; Righetti, D.; Hauffe, H. C.; Pedrotti, L.; Cagnacci, F.
10.1101/2024.08.03.606415 — ecology — Posted on 2024-08-06
4205 An Information Theory Framework for Movement Path Segmentation and Analysis
Sethi, V.; Spiegel, O.; Salter, R.; Cain, S.; Toledo, S.; Getz, W.
10.1101/2024.08.02.606194 — ecology — Posted on 2024-08-06
4207 Dynamics of Bagaza, West Nile, and Usutu viruses in Portugal revealed by long-term serological surveillance in red-legged partridges, 2018-2022
Fontoura-Goncalves, C.; Llorente, F.; Perez-Ramirez, E.; Jimenez-Clavero, M. A.; Costa, J. B.; de Mello, G.; Goncalves, D.; Alves, P. C.; Hofle, U.; Queiros, J.
10.1101/2024.08.02.606292 — immunology — Posted on 2024-08-06
4209 Cancer therapy via neoepitope-specific monoclonal antibody cocktails
Hartman, C. J.; Mohamed, A. O.; Shukla, G. S.; Pero, S. C.; Sun, Y.-J.; Rodriguez, R. S.; Genovese, N. F.; Kohler, N. M.; Hemphill, T. R.; Huang, Y. H.; Krag, D. N.; Ackerman, M. E.
10.1101/2024.08.02.606410 — immunology — Posted on 2024-08-06
4210 Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder
Green, N.; Gao, H.; Chu, X.; Yuan, Q.; McGuire, P.; Lai, D.; Jiang, G.; Xuei, X.; Reiter, J.; Stevens, J.; Sutherland, G.; Goate, A. M.; Pang, Z. P.; Slesinger, P.; Hart, R. P.; Tischfield, J. A.; Agrawal, A.; Wang, Y.; Duren, Z.; Edenberg, H.; Liu, Y.
10.1101/2024.08.02.606355 — neuroscience — Posted on 2024-08-06
4219 Expanding the Distribution and Phylogenetic Insights of Chrysobrycon mojicai in the Peruvian Amazon: Morphological and Molecular Analyses with Taxonomic Corrections
Chuctaya, J.; Ruiz-Tafur, M.; Faustino-Fuster, D.; Meza-Vargas, V.; Garcia-Davila, C. R.; Castro-Ruiz, D.; Angulo, C.; Vanegas-Rios, J. A.
10.1101/2024.08.02.606444 — zoology — Posted on 2024-08-06
4220 The intrinsic dimension of gene expression during cell differentiation
Biondo, M.; Cirone, N.; Valle, F.; Lazzardi, S.; Caselle, M.; Osella, M.
10.1101/2024.08.02.606382 — systems biology — Posted on 2024-08-06
4222 Physiological and Molecular Responses of Projected Future Temperatures on Potato Tuberization
Guillemette, A.; Hernandez Casanova, G.; Hamilton, J. P.; Pokorna, E.; Dobrev, P. I.; Motyka, V.; Rashotte, A. M.; Leisner, C.
10.1101/2024.08.02.606361 — plant biology — Posted on 2024-08-06
4223 Two types of regeneration mechanism in acute liver injury
Aoyagi, T.; Goya, T.; Imoto, K.; Azuma, Y.; Hioki, T.; Kohjima, M.; Tanaka, M.; Oda, Y.; Ogawa, Y.
10.1101/2024.08.04.606468 — pathology — Posted on 2024-08-06
4225 Thrombo-inflammation analyzed in a validated seven-layer platelet decision model: cellular decisions are tough problems fast and heuristically solved
Prada Salcedo, J.; Balkenhol, J.; Osmanoglu, O.; Afshar, M.; Kaltdorf, M.; Hoffmann, S.; von Mammen, S.; Heinze, K.; Schulze, H.; Dandekar, T.
10.1101/2024.08.02.606324 — bioinformatics — Posted on 2024-08-06
4226 Expression quantitative trait locus mapping in recombinant gametes using single nucleus RNA sequencing
Parker, M. T.; Amar, S.; Campoy, J. A.; Krause, K.; Tusso, S.; Marek, M.; Huettel, B.; Schneeberger, K.
10.1101/2024.08.02.606310 — bioinformatics — Posted on 2024-08-06
4227 Expanding the scope of a catalogue search to bioisosteric fragment merges using a graph database approach
Wills, S.; Sanchez-Garcia, R.; Roughley, S. D.; Merritt, A.; Hubbard, R. E.; von Delft, F.; Deane, C. M.
10.1101/2024.08.02.606367 — bioinformatics — Posted on 2024-08-06
4229 Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosis
Chouaib, A. A.; Chang, H.-F.; Khamis, O. M.; Echeverry, S.; Demeersseman, L.; Elizarova, S.; Daniel, J. A.; Valitutti, S.; Barg, S.; Pape, C.; Shaib, A. H.; Becherer, U.
10.1101/2024.08.02.606323 — bioengineering — Posted on 2024-08-06
4230 Multiplex genome editing eliminates the Warburg Effect without impacting growth rate in mammalian cells
Hefzi, H.; Martinez-Monge, I.; Marin de Mas, I.; Cowie, N. L.; Gomez Toledo, A.; Noh, S. M.; Karottki, K. J. l. C.; Decker, M.; Arnsdorf, J.; Camacho-Zaragoza, J. M.; Kol, S.; Schoffelen, S.; Pristovsek, N.; Hansen, A. H.; Miguez, A. A.; Bjorn, S. P.; Broendum, K. J. l. C. K.; Javidi, E. M.; Jensen, K. L.; Stangl, L.; Kreidl, E.; Kallehauge, T. B.; Ley, D.; Menard, P.; Petersen, H. M.; Sukhova, Z.; Bauer, A.; Casanova, E.; Barron, N.; Malstrom, J.; Nielsen, L. K.; Lee, G. M.; Kildegaard, H. F.; Voldborg, B. G.; Lewis, N. E.
10.1101/2024.08.02.606284 — bioengineering — Posted on 2024-08-06
4232 Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations
Bhattacharya, R.; Ward, T.; Kalejaiye, T. D.; Mishra, A.; Leeman, S.; Azaghi, H.; Seidman, J. G.; Seidman, C. E.; Musah, S.
10.1101/2024.08.02.606108 — bioengineering — Posted on 2024-08-06
4234 Probabilistic modeling reveals coordinated social interaction states and their multisensory bases
Stednitz, S. J.; Lesak, A.; Fecker, A.; Painter, P.; Washbourne, P.; Mazzucato, L.; Scott, E. K.
10.1101/2024.08.02.606104 — animal behavior and cognition — Posted on 2024-08-06
4235 Differential Expression Analysis for Spatially Correlated Data
Vasconcelos, A. G.; McGuire, D.; Simon, N.; Danaher, P.; Shojaie, A.
10.1101/2024.08.02.606405 — genomics — Posted on 2024-08-06
4236 Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk
Mummey, H.; Elison, W.; Korgaonkar, K.; Elgamel, R.; Kudtarkar, P.; Griffin, E.; Benaglio, P.; Miller, M.; Jha, A.; Manning Fox, J. E.; Mccarthy, M.; Preissl, S.; Gloyn, A. L.; Macdonald, P. E.; Gaulton, K. J.
10.1101/2024.08.03.606460 — genomics — Posted on 2024-08-06
4238 Diseases and invasive species have synergistic effects with other anthropogenic threats on the functional and phylogenetic diversity in Testudines and Crocodilia
Rodriguez-Caro, R. C.; Gumbs, R.; Gracia, E.; Blomberg, S. P.; Cayuela, H.; Grace, M. K.; Carmona, C. P.; Perez-Mendoza, H. A.; Gimenez, A.; Davis, K. J.; Salguero-Gomez, R.
10.1101/2024.08.02.606360 — ecology — Posted on 2024-08-06
4239 A high lipid diet leads to greater pathology and lower tolerance during infection
Perrine, W. G.; Sauer, E.; Love, A. C.; Morris, A. N.; Novotny, J.; DuRant, S.
10.1101/2024.08.02.606372 — ecology — Posted on 2024-08-06
4240 CHRONIC LUNG INFLAMMATION LEADS TO MYELOID SKEWING OF HEMATOPOIETIC STEM CELLS IN A CYSTIC FIBROSIS MOUSE MODEL
Braga, C. L.; Isler Mancuso, R.; Thompson, E. N.; Öz, H. H.; Gudneppanavar, R.; Zhang, P.-X.; Huang, P.; Murray, T.; Egan, M.; Krause, D. S.; Bruscia, E. M.
10.1101/2024.08.02.606400 — immunology — Posted on 2024-08-06
4244 RF Channel-Based Adaptive Beamforming for 3D Ultrasound Localization Microscopy
Chabouh, G.; Pialot, B.; Denis, L.; Dumas, R.; Couture, O.; Muleki Seya, P.; Varray, F.
10.1101/2024.08.02.606290 — physiology — Posted on 2024-08-06
4245 Cleavage of the vascular matrix attracts glioblastoma cells to infiltrate the brain parenchyma
Perryman, L.; Hoye, A.; Cox, T. R.; Baker, A.-M.; Strobech, J.; Leonte, L.; Singh, L. B.; Popov, S.; Lorentzen, L. G.; Reuten, R.; Skovgaard Poulsen, H.; Davies, M. J.; Jones, C.; Erler, J. T.
10.1101/2024.08.02.606279 — cancer biology — Posted on 2024-08-06
4246 Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis.
Korelova, K.; Prechova, M.; Frick, L.; Sarnova, L.; Bisht, P.; Novotna, P.; Kosla, J.; Bortel, P.; Borutzki, Y.; Bileck, A.; Gerner, C.; Rahbari, M.; Rahbari, N.; Birgin, E.; Kvasnicova, B.; Galisova, A.; Sulkova, K.; Bauer, A.; Jobe, N.; Tolde, O.; Sticova, E.; Rosel, D.; O Connor, T.; Otahal, M.; Jirak, D.; Heikenwalder, M.; Wiche, G.; Meier-Menches, S. M.; Gregor, M.
10.1101/2024.08.02.606331 — cancer biology — Posted on 2024-08-06
4247 Lipidome visualisation, comparison, and analysis in a vector space
Olzhabaev, T.; Müller, L.; Krause, D.; Schwudke, D.; Torda, A. E.
10.1101/2024.08.02.606134 — bioinformatics — Posted on 2024-08-06
4248 iSODA: A Comprehensive Tool for Integrative Omics Data Analysis in Single- and Multi-Omics Experiments
Olivier-Jimenez, D.; Rico, D. J. E.; Harari, O.; Cruchaga, C.; Ali, M.; Ori, A.; Di Fraia, D.; Cabukusta, B.; Henrie, A.; Giera, M. A.; Mohammed, Y.
10.1101/2024.08.02.605811 — bioinformatics — Posted on 2024-08-06
4252 Sensitivities in associating land-system archetypes with sustainability metrics: Insights from simulations
Varma, V.; Evans, P. M.; Butikofer, L.; Goodwin, C. E.; Pywell, R. F.; Redhead, J. W.; Storkey, J.; Bullock, J. M.; Mead, A.
10.1101/2024.08.01.606212 — ecology — Posted on 2024-08-06
4253 LONG-TERM ECOLOGICAL MONITORING IN INDIA: A SYNTHESIS
Tiruvaimozhi, Y. V.; Borah, J.; Kala, C. P.; Kunte, K.; Patel, B.; Sreejith, K. A.; Thadani, R.; Osuri, A. M.; Ghosh-Harihar, M.
10.1101/2024.08.02.606338 — ecology — Posted on 2024-08-06
4257 Temporal kinetics of brain state effects on visual perception
Schmid, P.; Klein, T.; Minakowski, P.; Sager, S.; Reichert, C.; Knight, R. T.; Duerschmid, S.
10.1101/2024.08.02.606289 — neuroscience — Posted on 2024-08-06
4259 Environmental and molecular noise buffering by the cyanobacterial clock in individual cells
Eremina, A.; Schwall, C.; Saez, T.; Witting, L.; Kohlheyer, D.; Martins, B. M. C.; Thomas, P.; Locke, J. C. W.
10.1101/2024.08.02.605997 — systems biology — Posted on 2024-08-06
4260 mosGraphGPT: a foundation model for multi-omic signaling graphs using generative AI
Zhang, H.; Huang, D.; Chen, E.; Cao, D.; Xu, T.; Dizdar, B.; Li, G.; Chen, Y.; Payne, P.; Province, M.; Li, F.
10.1101/2024.08.01.606222 — bioinformatics — Posted on 2024-08-06
4261 WITHDRAWN: Molecular Dynamics guided Brownian tomography of apoferritin in liquid water
Acosta-Gutierrez, S.; De Pace, C.; Ing, G.; Marchello, G.; Wilkinson, N.; Gervasio, F.; Ruiz-Perez, L.; Battaglia, G.
10.1101/2021.04.30.442083 — biophysics — Posted on 2024-08-06
4262 Evolution of apoptotic signalling pathways within lophotrochozoans
Horkan, H. R.; Popgeorgiev, N.; Vervoort, M.; Gazave, E.; Krasovec, G.
10.1101/2023.12.11.571055 — evolutionary biology — Posted on 2024-08-06
4264 The influence of the head model on magnetoencephalography-derived functional connectivity fingerprinting
Schelfhout, M.; Hinault, T. T.; Lago, S.; Arcara, G.; Amico, E.; Fraschini, M.; Marinazzo, D.
10.1101/2024.08.05.606621 — neuroscience — Posted on 2024-08-06
4266 Red blood cell-tumour cell interactions promote tumour cell progression
Pereira-Veiga, T.; Yanez-Gomez, C.; Pekkarinen, A.; Abuin, C.; Blechner, C.; Gonzalez-Conde, M.; Bauer, A. T.; Vidal-y-Sy, S.; Moustafa, A.; Siebels, B.; Davila-Ibanez, A. B.; Cabezas-Sainz, P.; Santos, M.; Sanchez, L.; Gorgulho, J.; Götze, J.; Meissner, K.; Cueva, J.; Palacios, P.; Cortegoso, A.; Curiel, T.; Rodriguez, C.; Carmona, M.; Peine, S.; Schmidt, M.; Heuer-Olewinski, N.; Reck, M.; Abdo, M.; Lopez-Lopez, R.; Windhorst, S.; Pantel, K.; Wikman, H.; Costa, C.
10.1101/2024.08.02.606121 — cancer biology — Posted on 2024-08-06
4267 Clonal evolutionary analysis reveals patterns of malignant transformation in pancreatic cancer from Intraductal Papillary Mucinous IPMN Neoplasms (IPMN)
Pea, A.; He, X.; Upstill-Goddard, R.; Luchini, C.; Santana, L. P. S.; Dreyer, S.; Jamieson, N.; Duthie, F.; MacKay, C.; Dickson, E.; Pulvirenti, A.; Rebus, S.; Genomics Innovation Alliance, ; Scottish Genome Partnership, ; Piccoli, P.; Sperandio, N.; Lawlor, R.; Milella, M.; Froeling, F.; Salvia, R.; Scarpa, A.; Bainkin, A.; Wedge, D.; Chang, D.
10.1101/2024.08.02.606217 — cancer biology — Posted on 2024-08-06
4268 Myeloid-instructed CD14+CD4+ T cells within the tumor microenvironment are associated with TNFα signaling and prolonged survival in non-small cell lung cancer
Marceaux, C.; Yokote, K.; Gayevskiy, V.; Batey, D.; Tarasova, I.; Choux, L.; Riley, L.; Tubau, N.; Hywood, J.; Christie, M.; Antippa, P.; Speed, T. P.; Rogers, K. L.; Phipson, B.; Asselin-Labat, M.-L.
10.1101/2024.08.02.606259 — cancer biology — Posted on 2024-08-06
4269 The intrinsically disordered N-terminus of SUMO1 is an intramolecular inhibitor of SUMO1 interactions
Richter, S. M.; Jin, F.; Ritterhoff, T.; Fergin, A.; Maurer, E.; Frank, A.; Daube, M.; Hajnal, A.; Klevit, R. E.; Gräter, F.; Flotho, A.; Melchior, F.
10.1101/2024.01.04.574143 — biochemistry — Posted on 2024-08-06
4271 An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration
Marefati, M.; Fernandez-Vallone, V.; Leprovots, M.; Vasile, G.; Libert, F.; Lefort, A.; Dinsart, G.; Weber, A.; Jetzer, J.; Garcia, M.-I.; Vassart, G.
10.1101/2024.03.11.584399 — developmental biology — Posted on 2024-08-06
4272 Mfn2 induces NCLX-mediated calcium release from mitochondria.
Kolitsida, P.; Saha, A.; Caliri, A. W.; Assali, E.; Riera, A. M.; Itskanov, S.; Magana, C. S.; Stork, B.; Shirihai, O. S.; Sekler, I.; Koehler, C. M.; van der Bliek, A. M.
10.1101/2024.08.05.606704 — cell biology — Posted on 2024-08-06
4273 Apical Size Reduction by Macropinocytosis Alleviates Tissue Crowding
Bresteau, E.; Suva, E. E.; Revell, C.; Hassan, O. A.; Grata, A.; Sheridan, J.; Mitchell, J.; Arvantis, C.; Korobova, F.; Woolner, S.; Jensen, O. E.; Mitchell, B.
10.1101/2024.08.05.606662 — cell biology — Posted on 2024-08-06
4275 High-intensity physiological activation disrupts the neural signatures of conflict processing
Avancini, C.; Ciria, L. F.; Alameda, C.; Palenciano, A. F.; Canales-Johnson, A.; Bekinschtein, T. A.; Sanabria, D.
10.1101/2023.07.31.550835 — neuroscience — Posted on 2024-08-06
4276 Evaluating permutation-based inference for partial least squares analysis of neuroimaging data
Danyluik, M.; Zeighami, Y.; Mukora, A.; Lepage, M.; Shah, J.; Joober, R.; Misic, B.; Iturria-Medina, Y.; Chakravarty, M.
10.1101/2024.08.02.606412 — neuroscience — Posted on 2024-08-06
4277 Effects of Aging, Fitness, and Cerebrovascular Status on White Matter Microstructural Health
Clements, G.; Camacho, P. B.; Bowie, D. C.; Low, K. A.; Sutton, B. P.; Gratton, G.; Fabiani, M.
10.1101/2024.08.04.606520 — neuroscience — Posted on 2024-08-06
4278 Multiscale heterogeneity of white matter morphometry in psychiatric disorders
Segal, A.; Smith, R. E.; Chopra, S.; Oldham, S.; Parkes, L.; Aquino, K. M.; Kia, S. M.; Wolfers, T.; Franke, B.; Hoogman, M.; Beckmann, C. F.; Westlye, L. T.; Andreassen, O. A.; Zaleskey, A.; Ben, H. J.; Davey, C. G.; Soriano-Mas, C.; Cardoner, N.; Tiego, J.; Yucel, M.; Braganza, L.; Suo, C.; Berk, M.; Cotton, S.; Bellgrove, M. A.; Marquand, A. F.; Fornito, A.
10.1101/2024.08.04.606523 — neuroscience — Posted on 2024-08-06
4279 A Framework to Identify Opportunities to Address Socioscientific Issues in the Elementary School Curricula: A Case Study from England, Italy, and Portugal
Pessoa, P.; de Lima, J.; Piacentini, V.; Realdon, G.; Jeffries, A.; Ometto, L.; Lopes, J. B.; Zeidler, D. L.; Fonseca, M. J.; Sousa, B.; Pinto, A.; Sa-Pinto, X.
10.1101/2024.08.02.606442 — scientific communication and education — Posted on 2024-08-06
4280 Comparative lifespan and healthspan of nonhuman primate species common to biomedical research
Huber, H. F.; Ainsworth, H. C.; Quillen, E. E.; Salmon, A.; Ross, C.; Azhar, A. D.; Bales, K.; Basso, M. A.; Coleman, K.; Colman, R.; Darusman, H. S.; Hopkins, B.; Hotchkiss, C. E.; Jorgensen, M. J.; Kavanagh, K.; Li, C.; Mattison, J. A.; Nathanielsz, P. W.; Saputro, S.; Scorpio, D. G.; Sosa, P.-M.; Vallender, E. J.; Wang, Y.; Zeiss, C. J.; Shively, C. A.; Cox, L. A.
10.1101/2024.07.31.606010 — physiology — Posted on 2024-08-06
4283 Proteome-Wide Bioinformatic Annotation and Functional Validation of the Monotopic Phosphoglycosyl Transferase Superfamily
Durand, T.; Dodge, G. J.; Siuda, R. P.; Higinbotham, H. R.; Arbour, C. A.; Ghosh, S.; Allen, K. N.; Imperiali, B.
10.1101/2024.07.10.602977 — biochemistry — Posted on 2024-08-06
4285 Genome-wide mapping of native co-localized G4s and R-loops in living cells
Liu, T.; Shen, X.; Ren, Y.; Lu, H.; Liu, Y.; Chen, C.; Yu, L.; Xue, Z.
10.1101/2024.06.03.597194 — genomics — Posted on 2024-08-06
4286 Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice
Noh, M.; Che, X.; Jin, X.; Lee, D.-K.; Kim, H.-J.; Park, D. R.; Lee, S. Y.; Lee, H.; Gardella, T. J.; Choi, J.-Y.; Lee, S.
10.1101/2024.03.13.584815 — genomics — Posted on 2024-08-06
4287 Non-linear transcriptional responses to gradual modulation of transcription factor dosage
Domingo, J.; Minaeva, M.; Morris, J. A.; Ghatan, S.; Ziosi, M.; Sanjana, N. E.; Lappalainen, T.
10.1101/2024.03.01.582837 — genomics — Posted on 2024-08-06
4288 Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states
Balasubramanian, R.; Kizhatil, K.; Li, T.; Tolman, N.; Bhandari, A.; Clark, G.; Bupp-Chickering, V.; Kelly, R. A.; Zhou, S.; Peregrin, J.; Simon, M.; Montgomery, C.; Stamer, W. D.; Qian, J.; John, S.
10.1101/2023.08.31.555823 — genomics — Posted on 2024-08-06
4289 Interpreting SNP heritability in admixed populations
Huang, J.; Kleman, N.; Basu, S.; Shriver, M. D.; Zaidi, A. A.
10.1101/2023.08.04.551959 — genetics — Posted on 2024-08-06
4290 Variant-to-function dissection of rare non-coding GWAS loci with high impact on blood traits
Tardaguila, M.; Von Schiller, D.; Colombo, M.; Gori, I.; Coomber, E. L.; Vanderstichele, T.; Benaglio, P.; Chiereghin, C.; Gerety, S. S.; Vuckovic, D.; Landini, A.; Clerici, G.; Albers, P. K.; Ray-Jones, H.; Burnham, K. L.; Tokolyi, A.; Persyn, E.; Spivakov, M.; Sankaran, V. G.; Walter, K.; Kundu, K.; Pirastu, N.; Inouye, M.; Paul, D. S.; Davenport, E.; Sahlen, P.; Watt, S.; Soranzo, N.
10.1101/2024.08.05.606572 — genetics — Posted on 2024-08-06
4291 Context effects on repair of 5'-overhang DSB induced by Cas12a in Arabidopsis.
Lageix, S.; Hernandez Sanchez-Rebato, M.; Gallego, M. E.; Verbeke, J.; Bidet, Y.; Viala, S.; White, C. I.
10.1101/2024.08.05.606594 — genetics — Posted on 2024-08-06
4293 Substantial hierarchical reductions of genetic and morphological traits in the evolution of rotiferan parasites
Herlyn, H.; Hembrom, A. A.; Tosar, J. P.; Mauer, K. M.; Schmidt, H.; Dezfuli, B. S.; Hankeln, T.; Bachmann, L.; Sarkies, P.; Peterson, K. J.; Fromm, B.
10.1101/2024.08.01.605096 — evolutionary biology — Posted on 2024-08-06
4295 Pregnancy Reduces Il33+ Hybrid Progenitor Accumulation in the Aged Mammary Gland
Olander, A.; Ramirez, C.; Haro-Acosta, V.; Medina, P.; Kaushik, S.; Jonsson, V. D.; Sikandar, S. S.
10.1101/2024.08.01.606240 — developmental biology — Posted on 2024-08-06
4302 Amyloid, Tau, and APOE in Alzheimer's Disease: Impact on White Matter Tracts
Chandio, B. Q.; Villalon-Reina, J. E.; Nir, T. M.; Thomopoulos, S. I.; Feng, Y.; Benavidez, S.; Jahanshad, N.; Harezlak, J.; Garyfallidis, E.; Thompson, P. M.; for the Alzheimer's Disease Neuroimaging Initiative,
10.1101/2024.08.05.606560 — neuroscience — Posted on 2024-08-06
4303 Individual alpha frequency tACS reduces functional connectivity across the default mode network
Carrasco-Gomez, M.; Cabrera-Alvarez, J.; Garcia-Colomo, A.; del Cerro-Leon, A.; Gomez-Ariza, C. J.; Santos, A.; Maestu, F.
10.1101/2024.08.04.606325 — neuroscience — Posted on 2024-08-06
4305 Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX
Vaskevicius, A.; Baronas, D.; Leitans, J.; Kvietkauskaite, A.; Ruksenaite, A.; Manakova, E.; Toleikis, Z.; Kaupinis, A.; Kazaks, A.; Gedgaudas, M.; Mickeviciute, A.; Juozapaitiene, V.; Schioth, H.; Jaudzems, K.; Valius, M.; Tars, K.; Grazulis, S.; Meyer-Almes, F.-J.; Matuliene, J.; Zubriene, A.; Dudutiene, V.; Matulis, D.
10.1101/2024.05.20.594908 — biophysics — Posted on 2024-08-06
4306 PUFA stabilizes a conductive state of the selectivity filter in IKs channels
Golluscio, A.; Eldstrom, J.; Jowais, J. J.; Perez, M. E.; Cunningham, K. P.; de La Cruz, A.; Wu, X.; Fedida, D.; Larsson, P.; Tieleman, D. P.; Corradi, V.
10.1101/2024.01.11.575247 — biophysics — Posted on 2024-08-06
4308 Polarization gratings aided common-path Hilbert holotomography for high-throughput lipid droplets content assay
Zdankowski, P.; Winnik, J.; Rogalski, M.; Marzejon, M. J.; Wdowiak, E.; Dudka, W.; Jozwik, M.; Trusiak, M.
10.1101/2024.06.14.598984 — bioengineering — Posted on 2024-08-06
4309 Enzymatic carbon-fluorine bond cleavage by human gut microbes
Probst, S. I.; Felder, F. D.; Poltorak, V.; Mewalal, R.; Blaby, I. K.; Robinson, S. L.
10.1101/2024.07.15.601322 — biochemistry — Posted on 2024-08-06
4312 PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription
Love, L.; Jutte, B. B.; Lindqvist, B.; Rhodjess, H.; Kieri, O.; Nowak, P.; Svensson, J. P.
10.1101/2024.03.17.583304 — microbiology — Posted on 2024-08-06
4313 Head down tilt 15° increases cerebral perfusion before recanalization in acute ischemic stroke: a pre-clinical MRI study.
Beretta, S.; Carone, D.; Cho, T.-H.; Vigano, M.; Diamanti, S.; Mariani, J.; Pedrazzini, F. A.; Bianchi, E.; Pini, C.; Bolbos, R.; Wiart, M.; Ferrarese, C.; Chauveau, F.
10.1101/2024.08.02.606281 — neuroscience — Posted on 2024-08-06
4315 Understanding the Sport Viewership Experience using Functional Near-Infrared Spectroscopy
Potwarka, L.; Safati, A.; Pappas, A.; Ramchandani, G.; Narraine, M.; Gurbez, N.; Hall, P.
10.1101/2024.08.01.606260 — neuroscience — Posted on 2024-08-06
4316 DeepResBat: deep residual batch harmonization accounting for covariate distribution differences
An, L.; Zhang, C.; Wulan, N.; Zhang, S.; Chen, P.; Ji, F.; Ng, K. K.; Chen, C.; Zhou, J. H.; Yeo, B. T. T.; the Alzheimer's Disease Neuroimaging Initiative, ; the Australian Imaging Biomarkers and Lifestyle Study of Aging,
10.1101/2024.01.18.574145 — neuroscience — Posted on 2024-08-06
4317 Multivalent Targeting of Blood-Brain Barrier LRP1 for Neurovascular Recovery Therapy for Alzheimer s Disease
Chen, J.; Pan, X.; Duro Castano, A.; Cai, H.; Guo, B.; Liu, X.; Yu, Y.; Lui, S.; Luo, K.; Ke, B.; Ruiz-Perez, L.; Wei, X.; Gong, Q.; Tian, X.; Battaglia, G.
10.1101/2024.05.06.592767 — neuroscience — Posted on 2024-08-06
4318 Micron-resolution fiber mapping in histology independent of sample preparation
Georgiadis, M.; auf der Heiden, F.; Abbasi, H.; Ettema, L.; Nirschl, J.; Moein Taghavi, H.; Wakatsuki, M.; Liu, A.; Ho, W. H. D.; Carlson, M.; Doukas, M.; Koppes, S. A.; Keereweer, S.; Sobel, R. A.; Setsompop, K.; Liao, C.; Amunts, K.; Axer, M.; Zeineh, M. M.; Menzel, M.
10.1101/2024.03.26.586745 — pathology — Posted on 2024-08-06
4320 Robust virtual staining of landmark organelles
Liu, Z.; Hirata Miyasaki, E.; Pradeep, S.; Rahm, J. V.; Foley, C.; Chandler, T.; Ivanov, I. E.; Woosley, H. O.; Lao, T.; Balasubramanian, A.; Marreiros, R.; Liu, C.; Leonetti, M. D.; Aviner, R.; Arias, C.; Jacobo, A.; Mehta, S. B.
10.1101/2024.05.31.596901 — bioinformatics — Posted on 2024-08-06
4322 Low-Cost Robotic Manipulation of Live Microtissues for Cancer Drug Testing
Stepanov, I.; Gottshall, N. R.; Ahmadianyazdi, A.; Sinha, D.; Lockhart, E.; Nguyen, T. N.; Hassan, S.; Horowitz, L.; Yeung, R.; Gujral, T. S.; Folch, A.
10.1101/2024.03.21.586169 — bioengineering — Posted on 2024-08-06
4325 Sirt5 regulates chondrocyte metabolism and osteoarthritis development through protein lysine malonylation
Liu, H.; Binoy, A.; Ren, S.; Martino, T. C.; Miller, A. E.; Willis, C. R.; Veerabhadraiah, S. R.; Sukul, A.; Bons, J.; Rose, J.; Schilling, B.; Jurynec, M. J.; Zhu, S.
10.1101/2024.07.23.604872 — cell biology — Posted on 2024-08-06
4326 Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells
Koike, S.; Tachikawa, M.; Tsutsumi, M.; Okada, T.; Nemoto, T.; Keino-Masu, K.; Masu, M.
10.1101/2023.12.17.572077 — cell biology — Posted on 2024-08-06
4328 Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils
Ravesloot-Chavez, M. M.; Van Dis, E.; Fox, D.; Anaya-Sanchez, A.; Espich, S.; Nguyenla, X. H.; Rawal, S. L.; Samani, H.; Ballinger, M. A.; Thomas, H.; Kotov, D. I.; Vance, R.; Nachman, M.; Stanley, S.
10.1101/2023.06.29.547125 — immunology — Posted on 2024-08-06
4329 Mapping patterns of thought onto brain activity during movie-watching
Wallace, R. S.; Mckeown, B.; Goodall-Halliwell, I.; Chitiz, L.; Forest, P.; Karapanagiotidis, T.; Mulholland, B.; Turnbull, A. G.; Vanderwal, T.; Hardikar, S.; Alam, T. G.; Bernhardt, B.; Wang, H.-T.; Strawson, W.; Milham, M.; Xu, T.; Margulies, D.; Poerio, G. L.; Jefferies, E. S.; Skipper, J. I.; Wammes, J.; Leech, R.; Smallwood, J.
10.1101/2024.01.31.578244 — neuroscience — Posted on 2024-08-06
4330 The polyadenylation landscape after in vivo long-term potentiation in the rat brain
Guminska, N.; Pauzin, F. P.; Kuzniewska, B.; Miłek, J.; Wardaszka, P.; Krawczyk, P. S.; Mroczek, S.; Jelen, S.; Pagenhart, P. U.; Bramham, C. R.; Dziembowska, M.; Dziembowski, A.
10.1101/2024.06.05.597605 — neuroscience — Posted on 2024-08-06
4331 The visuomotor transformations underlying target-directed behavior
Zhao, P.; Tong, Y.; Lazarte, I. P.; Khan, B.; Tian, G.; Chen, K. K. Y.; Lam, T. K. C.; Semmelhack, J. L.
10.1101/2024.05.07.592863 — neuroscience — Posted on 2024-08-06
4335 Perpetual bioplastic production by a cyanobacteria-dominated microbiome
Altamira, B.; Arnau Roca, M.; Lage, A.; Gonzalez-Flo, E.; Garcia, J.
10.1101/2023.11.06.565755 — bioengineering — Posted on 2024-08-06
4339 Compatibility of time-lapse dry incubator on in vitro production of bovine embryos
Tsuji, H.; Nagai, H.; Kobinata, S.; Koyama, H.; Khurchabilig, A.; Fukunaga, N.; Asada, Y.; Sugimura, S.
10.1101/2024.08.01.606272 — developmental biology — Posted on 2024-08-06
4341 Sex-specific behavioral and thalamo-accumbal circuit adaptations after oxycodone abstinence.
Alonso-Caraballo, Y.; Li, Y.; Constantino, N. J.; Neal, M. A.; Driscoll, G. S.; Mavrikaki, M.; Bolshakov, V. Y.; Chartoff, E. H.
10.1101/2024.08.01.605459 — neuroscience — Posted on 2024-08-06
4342 Model selection for spectral parameterization
Wilson, L. E.; da Silva Castanheira, J.; Kinder, B. L.; Baillet, S.
10.1101/2024.08.01.606216 — neuroscience — Posted on 2024-08-06
4343 mosGraphFlow: a novel integrative graph AI model mining disease targets from multi-omic data
Zhang, H.; Cao, D.; Xu, T.; Chen, E.; Li, G.; Chen, Y.; Payne, P.; Province, M.; Li, F.
10.1101/2024.08.01.606219 — bioinformatics — Posted on 2024-08-06
4345 PDK-1/S6K and mTORC1 bypass systemic growth restrictions to promote regeneration
Maya, A. V.; Nogay, L.; Heckmann, L.; Grass, I.; Kierdorf, K.; Buescher, J.; Classen, A.-K.
10.1101/2024.08.05.606658 — developmental biology — Posted on 2024-08-06
4347 Enforced specificity of an animal symbiosis
Wagner, J. M.; Wong, J. H.; Millar, J. G.; Haxhimali, E.; Bruckner, A.; Naragon, T. H.; Boedicker, J. Q.; Parker, J.
10.1101/2024.08.04.606548 — evolutionary biology — Posted on 2024-08-06
4348 Molecular hydrogen can minimize negative effects of heat stress on the hard coral genus Acropora
Ostendarp, M.; de Breuyn, M.; El-Khaled, Y. C.; Garcias-Bonet, N.; Carvalho, S.; Peixoto, R. S.; Wild, C.
10.1101/2024.08.02.606431 — ecology — Posted on 2024-08-06
4350 Two structurally mobile regions control the conformation and function of metamorphic meiotic HORMAD proteins
Barroso, C.; Prince, J. P.; Rattu, P.; Kounde, D.; Ferrandiz, N.; Khalid, S.; Martinez-Perez, E.
10.1101/2024.08.05.606648 — molecular biology — Posted on 2024-08-05
4353 A non-conducting role of the Cav1.4 Ca2+ channel drives homeostatic plasticity at the cone photoreceptor synapse
Maddox, W.; Ordemann, G. J.; de la Rosa Vazquez, J.; Huang, A.; Gault, C.; Wisner, S. R.; Randall, K.; Futagi, D.; Salem, N. A.; Mayfield, R. D.; Zemelman, B. V.; DeVries, S.; Hoon, M.; Lee, A.
10.1101/2023.12.05.570129 — neuroscience — Posted on 2024-08-06
4356 MicroCT-based imaging of microvasculature within bone and peri-implant tissues
Haberthür, D.; Khoma, O.-Z.; Hoessly, T.; Zoni, E.; Kruithof-de Julio, M.; Ryan, S. D.; Grunewald, M.; Bellon, B.; Sandgren, R.; Pippenger, B. E.; Bosshardt, D.; Djonov, V.; Hlushchuk, R.
10.1101/2023.03.08.531678 — physiology — Posted on 2024-08-06
4358 Cryo-EM phase-plate images reveal unexpected levels of apparent specimen damage
Remis, J.; Petrov, P. N.; Zhang, J. T.; Axelrod, J. J.; Cheng, H.; Sandhaus, S.; Mueller, H.; Glaeser, R. M.
10.1101/2024.08.04.606536 — biophysics — Posted on 2024-08-06
4359 Snapshots of acetyl-CoA synthesis, the final step of CO2 fixation in the Wood-Ljungdahl pathway
Yin, M. D.; Lemaire, O. N.; Rosas-Jimenez, J. G.; Belhamri, M.; Shevchenko, A.; Hummer, G.; Wagner, T.; Murphy, B. J.
10.1101/2024.08.05.606187 — biophysics — Posted on 2024-08-06
4360 Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease
Hall, P.-R.; Jouen-Tachoire, T.; Schewe, M.; Proks, P.; Baukrowitz, T.; Carpenter, E. P.; Newstead, S.; Rodstrom, K.; Tucker, S. J.
10.1101/2024.08.05.606641 — biophysics — Posted on 2024-08-06
4365 Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy
Pakharukova, N.; Thomas, B. N.; Bansia, H.; Li, L.; Abzalimov, R. R.; Kim, J.; Kahsai, A. W.; Pani, B.; Bassford, D. K.; Liu, S.; Zhang, X.; des Georges, A.; Lefkowitz, R. J.
10.1101/2024.07.31.605623 — biochemistry — Posted on 2024-08-06
4366 Octopus can use odor plumes to find food
Weertman, W. L.; Gopal, V.; Sivitilli, D. M.; Scheel, D.; Gire, D. H.
10.1101/2024.08.02.606436 — animal behavior and cognition — Posted on 2024-08-06
4370 C-COMPASS: A Neural Network Tool for Multi-Omic Classification of Cell Compartments
Haas, D. T.; Trautmann, E. M.; Mao, X.; Gerl, M.; Klose, C.; Cheng, X.; Hasenauer, J.; Krahmer, N.
10.1101/2024.08.05.606647 — cell biology — Posted on 2024-08-05
4372 The molecular basis of lamin-specific chromatin interactions
Wang, B.; Kronenberg-Tenga, R.; Rosti, V.; Di Patrizio Soldateschi, E.; Luo, Q.; Pinet, L.; Eibauer, M.; Boujemaa-Paterski, R.; Schuler, B.; Lanzuolo, C.; Medalia, O.
10.1101/2024.08.05.604734 — cell biology — Posted on 2024-08-05
4374 Tet2 loss suppress α-synuclein pathology by stimulating ciliogenesis
Quansah, E.; Vatsa, N.; Ensink, E.; Brown, J.; Cave, T.; Aguileta, M.; Kuhn, E.; Lindquist, A.; Gilliland, C.; Steiner, J. A.; Escobar Gavis, M. L.; Milciute, M.; Henderson, M.; Brundin, P.; Brundin, L.; Marshall, L. L.; Gordevicius, J.
10.1101/2024.08.02.606408 — neuroscience — Posted on 2024-08-06
4375 HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease
Kealy, D.; Ellerington, R.; Bansal, S.; Zeng, A. G. X.; Medeiros, J. J. F.; West, K. A.; Blacknell, N.-M.; Hawley, C. A.; Lukaszonek, J.; Gawne, R.; Khoo, H. M.; Caalim, G.; Drylie, B.; Chatzigerou, J.; Rodriguez Lima Ferreira, B.; Wang, G.; Fielding, A. K.; Kent, D.; Psaila, B.; Wilkinson, A. C.; Holding, A. N.; Hitchcock, I. S.; Mason, A. S.; Gupta, V.; Dick, J.; Bridge, K. S.
10.1101/2024.07.02.601518 — cancer biology — Posted on 2024-08-06
4378 Is tumor mutational burden predictive of response to immunotherapy?
Gurjao, C.; Tsukrov, D.; Imakaev, M.; Luquette, L. J.; Mirny, L. A.
10.1101/2020.09.03.260265 — genomics — Posted on 2024-08-06
4382 Aversion-induced drug taking and escape behavior involve similar nucleus accumbens core dopamine signaling signatures
Grafelman, E. M.; Cote, B. E.; Vlach, L.; Geise, E.; Padula, G. N.; Wheeler, D. S.; Hearing, M. C.; Mantsch, J. R.; Wheeler, R. A.
10.1101/2024.08.05.606651 — neuroscience — Posted on 2024-08-05
4383 Amyloid, Tau, and APOE in Alzheimer's Disease: Impact on White Matter Tracts
Chandio, B. Q.; Villalon-Reina, J. E.; Nir, T. M.; Thomopoulos, S. I.; Feng, Y.; Benavidez, S.; Jahanshad, N.; Harezlak, J.; Garyfallidis, E.; Thompson, P. M.
10.1101/2024.08.05.606560 — neuroscience — Posted on 2024-08-05
4384 The molecular diversity of hippocampal regions and strata at synaptic resolution revealed by integrated transcriptomic and proteomic profiling
Kaulich, E.; Waselenchuk, Q.; Fuerst, N.; Desch, K.; Mosbacher, J.; Ciirdaeva, E.; Juengling, M.; Tushev, G.; Langer, J.; Schuman, E. M.
10.1101/2024.08.05.606570 — neuroscience — Posted on 2024-08-05
4385 Investigating cocaine- and abstinence-induced effects on astrocyte gene expression in the nucleus accumbens
Franklin, J. P.; Testen, A.; Mieczkowski, P. A.; Hepperla, A.; Crynen, G.; Simon, J. M.; Wood, J. D.; Harder, E. V.; Bellinger, T. J.; Witt, E. A.; Powell, N. L.; Reissner, K. J.
10.1101/2024.08.05.606656 — neuroscience — Posted on 2024-08-05
4386 A familial, telomere-to-telomere reference for human de novo mutation and recombination from a four-generation pedigree
Porubsky, D.; Dashnow, H.; Sasani, T. A.; Logsdon, G. A.; Hallast, P.; Noyes, M. D.; Kronenberg, Z. N.; Mokveld, T.; Koundinya, N.; Nolan, C.; Steely, C. J.; Guarracino, A.; Dolzhenko, E.; Harvey, W. T.; Rowell, W. J.; Grigorev, K.; Nicholas, T. J.; Oshima, K. K.; Lin, J.; Ebert, P.; Watkins, W. S.; Leung, T. Y.; Hanlon, V. C. T.; McGee, S.; Pedersen, B. S.; Goldberg, M. E.; Happ, H. C.; Jeong, H.; Munson, K. M.; Hoekzema, K.; Chan, D. D.; Wang, Y.; Knuth, J.; Garcia, G. H.; Fanslow, C.; Lambert, C.; Lee, C.; Smith, J. D.; Levy, S. E.; Mason, C. E.; Garrison, E.; Lansdorp, P. M.; Neklason, D.
10.1101/2024.08.05.606142 — genomics — Posted on 2024-08-05
4387 Sex-specific effects of early-life adversity on adult fitness in a wild mammal
Drake, E. D.; Ravindran, S.; Bal, X.; Pilkington, J. G.; Pemberton, J. M.; Nussey, D. H.; Froy, H.
10.1101/2024.08.05.606598 — evolutionary biology — Posted on 2024-08-05
4389 Random Sanitization in DNA information storage using CRISPR-Cas12a
Shen, H.; Weng, Z.; Zhao, H.; Song, H.; Wang, F.; Fan, C.; Song, P.
10.1101/2024.08.04.606549 — synthetic biology — Posted on 2024-08-05
4390 A biodegradable and restorative peripheral neural interface for the interrogation of neuropathic injuries
Wang, L.; Zhang, T.; Lei, J.; Wang, S.; Guan, Y.; Chen, K.; Li, C.; Song, Y.; Li, W.; Wang, S.; Jia, Z.; Chen, S.; Bai, J.; Yu, B.; Yang, C.; Sun, P.; Wang, Q.; Sheng, X.; Peng, J.; Fan, Y.; Wang, L.; Zhang, M.; Wang, Y.; Yin, L.
10.1101/2024.08.05.606715 — bioengineering — Posted on 2024-08-05
4392 ECT2 peptide sequences outside the YTH domain regulate its m6A-RNA binding
Seigneurin-Berny, D.; Karczewski, C.; Delaforge, E.; Yaacoub, K.; Gaspar Litholdo, C.; Favory, J.-J.; Ringkjobing Jensen, M.; Bousquet-Antonelli, C.; Verdel, A.
10.1101/2024.08.05.606563 — biochemistry — Posted on 2024-08-05
4395 The molecular basis of Human FN3K mediated phosphorylation of glycated substrate
Garg, A.; On, K. F.; Xiao, Y.; Elkayam, E.; Cifani, P.; David, Y.; Joshua-Tor, L.
10.1101/2024.08.05.606604 — biochemistry — Posted on 2024-08-05
4397 Chromatin-dependent motif syntax defines differentiation trajectories
Durdu, S.; Iskar, M.; Isbel, L.; Hoerner, L.; Wirbelauer, C.; Burger, L.; Hess, D.; Iesmantavicius, V.; Schubeler, D.
10.1101/2024.08.05.606702 — genomics — Posted on 2024-08-05
4398 Variant-to-function dissection of rare non-coding GWAS loci with high impact on blood traits
Tardaguila, M.; Soranzo, N.; Von Schiller, D.; Colombo, M.; Gori, I.; Coomber, E. L.; Vanderstichele, T.; Benaglio, P.; Chiereghin, C.; Gerety, S. S.; Vuckovic, D.; Landini, A.; Clerici, G.; Albers, P. K.; Walter, K.; Kundu, K.; Pirastu, N.; Ray-Jones, H.; Burnham, K. L.; Tokolyi, A.; Persyn, E.; Spivakov, M.; Watt, S.; Inouye, M.; Paul, D. S.; Davenport, E.; Sahlen, P.; Sankaran, V. G.
10.1101/2024.08.05.606572 — genetics — Posted on 2024-08-05
4400 Inferring the composition of a mixed culture of natural microbial isolates by deep sequencing
Voorhies, M. S.; Joehnk, B.; Uehling, J.; Walcott, K.; Dubin, C.; Mead, H.; Homer, C.; Galgiani, J.; Barker, B.; Brem, R.; Sil, A.
10.1101/2024.08.05.606565 — genetics — Posted on 2024-08-05
4401 Context effects on repair of 5'-overhang DSB induced by Cas12a in Arabidopsis.
Lageix, S.; Hernandez Sanchez-Rebato, M.; Gallego, M. E.; Verbeke, J.; Bidet, Y.; Viala, S.; White, C. I.
10.1101/2024.08.05.606594 — genetics — Posted on 2024-08-05
4403 Uncoupling the functional roles of Coronavirus Nsp1
Baeumlin, E.; Andenmatten, D.; Luginbuehl, J.; Lalou, A.; Schwaller, N.; Karousis, E. D.
10.1101/2024.08.05.606569 — molecular biology — Posted on 2024-08-05
4404 An enhanced Eco1 retron editor enables precision genome engineering in human cells from a single-copy integrated lentivirus
Cattle, M. A.; Aguado, L. C.; Sze, S.; Wang, D. Y.; Papagiannakopoulos, T.; Smith, S.; Rice, C. M.; Schneider, W. M.; Poirier, J. T.
10.1101/2024.08.05.606586 — molecular biology — Posted on 2024-08-05
4405 HIF1α controls steroidogenesis under acute hypoxic stress
Ariyeloye, S.; Watts, D.; Jaykar, M.; Ermis, C.; Krueger, A.; Kaden, D.; Stepien, B. K.; Alexaki, V. I.; Peitzsch, M.; Bechmann, N.; El-Armouche, A.; Wielockx, B.
10.1101/2024.08.05.606625 — molecular biology — Posted on 2024-08-05
4406 Circadian clock disruption and growth of kidney cysts in autosomal dominant polycystic kidney disease
Jamadar, A.; Ward, C. J.; Remadevi, V.; Varghese, M. M.; Pabla, N. S.; Gumz, M. L.; Rao, R.
10.1101/2024.08.05.606676 — molecular biology — Posted on 2024-08-05
4407 A modular self-assembling and self-adjuvanting multiepitope peptide nanoparticle vaccine platform to improve the efficacy and immunogenicity of BCG
Zhao, G.; Sathkumara, H.; Miranda-Hernandez, S.; Seifert, J.; Valencia Hernandez, A. M.; Puri, M.; Huang, W.; Toth, I.; Daly, N.; Skwarczynski, M.; Kupz, A.
10.1101/2024.08.04.606253 — microbiology — Posted on 2024-08-05
4409 Molecular Tracking and Cultivation Reveal Ammonia Oxidizing Archaea as Integral Members of the Human Skin Microbiome
Mahnert, A.; Dreer, M.; Perier, U.; Melcher, M.; Duller, S.; Lehnen, A.; Goessler, T.; Brunner, D.; Graier, T.; Wolf, P.; Ponce-Toledo, R. I.; Hodgskiss, L.; Kerou, M.; Moissl-Eichinger, C.; Schleper, C.
10.1101/2024.08.05.606590 — microbiology — Posted on 2024-08-05
4411 Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis.
March, V. F. A.; Maghradze, N.; Mchedlishvili, K.; Avaliani, T.; Aspindzelashvili, R.; Avaliani, Z.; Kipiani, M.; Tukvadze, N.; Jugheli, L.; Bouaouina, S.; Doetsch, A.; Goig, G. A.; Gagneux, S.; Borrell Farnov, S.
10.1101/2024.08.05.606579 — microbiology — Posted on 2024-08-05
4414 Mapping Kappa Opioid Receptor Binding in Titi Monkeys with 11C-GR103545 PET
Almeida, A. J. D.; Hobson, B. A.; Savidge, L. E.; Manca, C.; Paulus, J. P.; Bales, K. L.; Chaudhari, A. J.
10.1101/2024.08.01.606042 — neuroscience — Posted on 2024-08-05
4418 Rapamycin increases murine lifespan but does not reduce mineral volume in the Matrix GLA Protein (MGP) knockout mouse model of medial arterial calcification.
Behzadi, P.; Cuevas, R. A.; Crane, A.; Wendling, A. A.; Chu, C. C.; Moorhead, W. J.; Wong, R.; Brown, M.; Tamakloe, J.; Suresh, S.; Saleh, P.; Jaffe, I. A.; Kuipers, A. L.; Lukashova, L.; Verdelis, K.; St. Hilaire, C.
10.1101/2024.08.01.606196 — physiology — Posted on 2024-08-05
4419 Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles
Rosenblum, Y.; Jafarzadeh Esfahani, M.; Adelhöfer, N.; Zerr, P.; Furrer, M.; Huber, R.; Roest, F. F.; Steiger, A.; Zeising, M.; Horvath, C. G.; Schneider, B.; Bodizs, R.; Dresler, M.
10.1101/2023.07.04.547323 — neuroscience — Posted on 2024-08-05
4421 Ubiquitin-specific protease 8 controls B-cell proteostasis and survival representing a target in multiple myeloma
Dufner, A.; Thery, F.; Monaco, G.; Lazarevic, J. L.; Gorka, O.; Chevalier, N.; Frosch, M.; van der Heden van Noort, G. J.; Prinz, M.; Gross, O.; Geurink, P. P.; Schamel, W. W.; Heissmeyer, V.; Denzel, M. S.; Bruns, H.; Schemionek, M.; Impens, F.; Knobeloch, K.-P.
10.1101/2024.04.26.591134 — molecular biology — Posted on 2024-08-05
4422 IPMK Deficiency Reduces Skeletal Muscle Oxidative Metabolism and Exercise Capacity
Lee, J.-H.; Jung, I.-R.; Tu-Sekine, B.; Jin, S.; Anokye-Danso, F.; Ahima, R. S.; Kim, S. F.
10.1101/2024.07.28.605526 — molecular biology — Posted on 2024-08-05
4427 The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer
Souto, E. P.; Gong, P.; Landua, J. D.; Srinivasan, R. R.; Ganesan, A.; Dobrolecki, L. E.; Purdy, S. C.; Pan, X.; Zeosky, M.; Chung, A.; Yi, S. S.; Ford, H. L.; Lewis, M. T.
10.1101/2023.09.15.557958 — cancer biology — Posted on 2024-08-05
4428 A modified dual preparatory method for improved isolation of nucleic acids from laser microdissected fresh-frozen human cancer tissue specimens
Kimble, D. C.; Litzi, T. J.; Snyder, G.; Olowu, V.; TaQee, S.; Conrads, K. A.; Loffredo, J.; Bateman, N. W.; Alba, C.; Rice, E.; Shriver, C. D.; Maxwell, G. L.; Dalgard, C.; Conrads, T. P.
10.1101/2024.08.02.606193 — biochemistry — Posted on 2024-08-05
4431 Involvement of OsS40-14 in ROS and plastid organization related regulatory networks of dark-induced senescence in rice
Habiba, H.; Fan, C.; Hong, W.; Shi, X.; Wang, X.; Wang, W.; Lin, W.; Li, Y.; Ain, N. u.; Miao, Y.; Zheng, X.
10.1101/2024.08.01.606232 — plant biology — Posted on 2024-08-05
4433 Enhanced pollen tube performance at high temperature contributes to thermotolerant fruit production in tomato.
Yimga, S. V. O.; Palaniappan, M.; Pryze, K.; Jong, E.; Ali, M. F.; Styler, B.; Almasaud, R. A.; Harkey, A. F.; Reid, R. W.; Loraine, A. E.; Smith, S. E.; Muday, G. K.; Pease, J. B.; Palanivelu, R.; Johnson, M. A.
10.1101/2024.08.01.606234 — plant biology — Posted on 2024-08-05
4434 Low-ABC: a robust demographic Inference from low-coverage whole-genome data through ABC
Vizzari, M. T.; Ghirotto, S.; Agostini, R. B.; Delser, P. M.; Cassidy, L.; Manica, A.; Benazzo, A.
10.1101/2024.08.01.606209 — genomics — Posted on 2024-08-05
4435 Genomic prediction of cereal crop architecture traits using models informed by gene regulatory circuitries from maize
Bertolini, E.; Manjunath, M.; Ge, W.; Murphy, M. D.; Inaoka, M.; Fliege, C.; Eveland, A. L.; Lipka, A. E.
10.1101/2024.08.01.606170 — genetics — Posted on 2024-08-05
4436 Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models
Lim, J. L.; Jensen, S. M.; Plomp, J. J.; Vankerckhoven, B.; Kneip, C.; Coppejans, R.; Steyaert, C.; Moens, K.; De Clercq, L.; Tannemaat, M. R.; Ulrichts, P.; Silence, K.; van der Maarel, S. M.; Vergoossen, D. L. E.; Vanhauwaert, R.; Verschuuren, J. J.; Huijbers, M. G.
10.1101/2024.08.01.606156 — neuroscience — Posted on 2024-08-05
4440 Mechanical Implications of Cellular Viscoelasticity, Cortex Polarity, Superelasticity, and Cell-Cell Junctions in Curved Tissues
Perez-Tirado, A.; Unkelbach, U.; Oswald, T. A.; Rheinlaender, J.; Schaeffer, T. E.; Mukenhirn, M.; Honigmann, A.; Janshoff, A.
10.1101/2024.08.01.606202 — biophysics — Posted on 2024-08-05
4441 Resources modulate developmental shifts but not infection tolerance upon coinfection in an insect system
Schulz, N. K. E.; Asgari, D.; Liu, S.; Birnbaum, S. S. L.; Williams, A. M.; Prakash, A.; Tate, A. T.
10.1101/2024.08.01.606236 — ecology — Posted on 2024-08-05
4446 Screening great ape museum specimens for DNA viruses
Haemmerle, M.; Guellil, M.; Cheronet, O.; Sawyer, S.; Ruiz-Gartzia, I.; Lizano, E.; Rymbekova, A.; Gelabert, P.; Bernardi, P.; Han, S.; Trgovec-Greif, L.; Rattei, T.; Schuenemann, V. J.; Marques-Bonet, T.; Guschanski, K.; Calvignac-Spencer, S.; Pinhasi, R.; Kuhlwilm, M.
10.1101/2024.04.25.591107 — genomics — Posted on 2024-08-05
4447 Nanoscale volumetric fluorescence imaging via photochemical sectioning
Wang, W.; Ruan, X.; Liu, G.; Milkie, D. E.; Li, W.; Betzig, E.; Upadhyayula, S.; Gao, R.
10.1101/2024.08.01.605857 — neuroscience — Posted on 2024-08-05
4450 Increased listening effort and cochlear neural degeneration underlie behavioral deficits in speech perception in noise in normal hearing middle-aged adults.
Zink, M. E.; Zhen, L.; McHaney, J. R.; Klara, J.; Yurasits, K.; Cancel, V.; Flemm, O.; Mitchell, C.; Datta, J.; Chandrasekaran, B.; Parthasarathy, A.
10.1101/2024.08.01.606213 — neuroscience — Posted on 2024-08-05
4454 Breathwork-Induced Psychedelic Experiences Modulate Neural Dynamics
Lewis-Healey, E.; Tagliazucchi, E.; Canales-Johnson, A.; Bekinschtein, T.
10.1101/2024.02.19.580985 — neuroscience — Posted on 2024-08-05
4464 Simultaneous silencing of gut nucleases and a vital target gene by adult dsRNA feeding enhances RNAi efficiency and mortality in Ceratitis capitata adults.
Saccone, G.; Aceto, S.; Salvemini, M.; Volpe, G.; Pennacchio, F.; Mazzucchiello, S. M.; Lucibelli, F.; Varone, M.; Baccaro, D.; Mattei, I.; Giordano, E.; Di Lelio, I.; Becchimanzi, A.; Rosati, N.
10.1101/2024.08.01.605863 — genetics — Posted on 2024-08-05
4467 Differential regulation of BAX and BAK apoptotic activity revealed by a novel small molecule
Li, K.; Yap, Y. Q.; Moujalled, D.; Sumardy, F.; Khakham, Y.; Giorgiou, A.; Jahja, M.; Lew, T.; DeSilva, M.; Luo, M.; Gong, J.; Roberts, A.; Yuan, Z.; Birkinshaw, R.; Czabotar, P. E.; Lowes, K.; Huang, D.; Kile, B.; Wei, A.; Dewson, G.; van Delft, M. F.; Lessene, G.
10.1101/2024.08.04.605933 — cell biology — Posted on 2024-08-05
4473 Chromosome structural rearrangements in invasive haplodiploid ambrosia beetles revealed by the genomes of Euwallacea fornicatus and Euwallacea similis (Coleoptera, Curculionidae, Scolytinae)
Bickerstaff, J. R.; Walsh, T.; Court, L.; Pandey, G.; Ireland, K.; Cousins, D.; Caron, V.; Wallenius, T.; Slipinski, A.; Rane, R.; Escalona, H.
10.1101/2024.06.25.600716 — genomics — Posted on 2024-08-04
4474 Social and environmental predictors of gut microbiome age in wild baboons
Dasari, M. R.; Roche, K. E.; Jansen, D.; Anderson, J.; Alberts, S. C.; Tung, J.; Gilbert, J. A.; Blekhman, R.; Mukherjee, S.; Archie, E.
10.1101/2024.08.02.605707 — evolutionary biology — Posted on 2024-08-04
4476 Substantial hierarchical reductions of genetic and morphological traits in the evolution of rotiferan parasites
Herlyn, H.; Hembrom, A. A.; Tosar, J. P.; Mauer, K. M.; Schmidt, H.; Dezfuli, B. S.; Bachmann, L.; Sarkies, P.; Peterson, K. J.; Fromm, B.
10.1101/2024.08.01.605096 — evolutionary biology — Posted on 2024-08-04
4478 Nematodes Vector Bacteriophages in Compost and Soil
van Sluijs, L.; Dietz, C.; Van Noort, F.; Helder, J.; Zwart, M. W.; Mason-Jones, K.
10.1101/2024.08.02.605737 — ecology — Posted on 2024-08-04
4479 Factors affecting the individual probability of infection with a prevalent pathogen (Mycoplasma) and the effect on Griffon vultures' movement behavior
Anglister, N.; Crafton, M.; Avraham Saada, O.; Acacio, M.; Vaadia, G.; Hatzofe, O.; Miller, Y.; Mikula, I.; Pinter-Wollman, N.; Lysynyansky, I.; Spiegel, O.
10.1101/2024.08.01.606137 — ecology — Posted on 2024-08-04
4481 CyNET- a network analysis framework for high dimensionality, system level analyses of the functional Immunome
Kumar, P.; Yeo, J. G.; Poh, S. L.; Nur Hazirah, S.; Sutamam, N. B.; ang, G. W.; Chellamuthu, V. R.; Wasser, M.; Yeo, K. T.; Leong, J. Y.; Ramakrishna, L.; Arkachaisri, T.; Albani, S.
10.1101/2024.07.15.603495 — immunology — Posted on 2024-08-04
4485 Ontology-based modeling, integration, and analysis of heterogeneous clinical, pathological, and molecular kidney data for precision medicine
He, Y.; Barisoni, L.; Rosenberg, A. Z.; Robinson, P. N.; Diehl, A. D.; Chen, Y.; Phuong, J. P.; Hansen, J.; Herr, B. W.; Borner, K.; Schaub, J.; Bonevich, N.; Arnous, G.; Boddapati, S.; Zheng, J.; Alakwaa, F.; Sarder, P.; Duncan, W. D.; Liang, C.; Valerius, M. T.; Jain, S.; Iyengar, R.; Himmelfarb, J.; Kretzler, M.; Kidney Precision Medicine Project,
10.1101/2024.04.01.587658 — bioinformatics — Posted on 2024-08-04
4487 Heterogeneity of the human immune response to malaria infection and vaccination driven by latent cytomegalovirus infection
Mukhiya, R.; Fleischmann, W. A.; Loughland, J. R.; Chan, J.-A.; de Labastida Rivera, F.; Andrew, D.; Beeson, J. G.; McCarthy, J. S.; Barber, B.; Lopez, J. A.; Engwerda, C.; Thomson-Luque, R.; Boyle, M. J.
10.1101/2024.04.28.591548 — immunology — Posted on 2024-08-04
4488 The multi-level effect of chlorpyrifos during clownfish metamorphosis
Reynaud, M.; Vianello, S.; Lee, S.-H.; Salis, P.; Dusseune, M.; Wu, K.; Frederich, B.; Lecchini, D.; Besseau, L.; Roux, N.; Laudet, V.
10.1101/2024.08.02.606305 — developmental biology — Posted on 2024-08-04
4489 Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR-ncPRC1.1
Wolf van der Meer, J.; Larue, A.; van der Knaap, J.; Chalkley, G.; Sijm, A.; Beikmohammadi, L.; Kozhevnikova, E. N.; van der Vaart, A.; Tilly, B.; Bezstarosti, K.; Dekkers, D. H. W.; Doff, W. A. S.; van de Wetering-Tieleman, J.; Lanko, K.; Barakat, T. S.; Allertz, T.; van Haren, J.; Demmers, J. A.; Atlasi, Y.; Verrijzer, C. P.
10.1101/2024.08.04.606521 — molecular biology — Posted on 2024-08-04
4490 Microcystins are critical for the toxic Microcystis to survive long-term nitrogen starvation
Lian, X.-Y.; Qiu, G.-W.; Zheng, W.-C.; Shang, J.-L.; Xu, H.-F.; Dai, G.-Z.; Gan, N.-Q.; Zhang, Z.-C.; Qiu, B.-S.
10.1101/2024.08.03.606466 — microbiology — Posted on 2024-08-04
4496 Insertion and Anchoring of HIV-1 Fusion Peptide into Complex Membrane Mimicking Human T-cell
Zhao, M.; Lopes, L. J. S.; Sahni, H.; Yadav, A.; Do, H. N.; Reddy, T.; Lopez, C. A.; Neale, C.; Gnanakaran, S.
10.1101/2024.08.02.606381 — biophysics — Posted on 2024-08-04
4500 Intra-subgenome regulation induces unbalanced expression and function among bread wheat homoeologs
Wang, X.; Liu, Y.; Zhao, P.; Hou, W.; Cheng, M.; Shi, X.; Simmonds, J.; Borrill, P.; Ji, W.; Xu, S.
10.1101/2024.08.01.606124 — genomics — Posted on 2024-08-04
4502 A new clade of pararetroviruses distantly related to hepadnaviruses and nackednaviruses
Buigues, J.; Vinals, A.; Martinez-Recio, R.; Monros, J. S.; Cuevas, J. M.; Sanjuan, R.
10.1101/2024.08.02.606351 — evolutionary biology — Posted on 2024-08-04
4503 Root traits and tree functional groups determine variability in root exudation and N uptake rates in mature temperate trees
Oh, Y. E.; Midgley, M. G.; McCormack, M. L.; Beidler, K. V.; McCall, M.; Henderson, S.; Braghiere, R. K.; Phillips, R. P.
10.1101/2024.08.01.606171 — ecology — Posted on 2024-08-04
4508 Conservation of dichromatin organization along regional centromeres
Dubocanin, D.; Hartley, G. A.; Cortes, A. E. S.; Mao, Y.; Hedouin, S.; Ranchalis, J. E.; Agarwal, A.; Logsdon, G.; Munson, K. M.; Real, T. D.; Mallory, B. J.; Eichler, E. E.; Biggins, S.; O'Neill, R. J.; Stergachis, A. B.
10.1101/2023.04.20.537689 — genomics — Posted on 2024-08-04
4510 Proteogenomics guided identification of functional neoantigens in non-small cell lung cancer
Nicholas, B.; Bailey, A.; McCann, K. J.; Wood, O.; Currall, E.; Johnson, P.; Elliott, T.; Ottensmeier, C.; Skipp, P.
10.1101/2024.05.30.596609 — immunology — Posted on 2024-08-04
4511 Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus
Iannitelli, A. F.; Hassanein, L.; Mulvey, B.; Blankenship, H.; Liles, L. C.; Sharpe, A. L.; Pare, J.-F.; Segal, A.; Sloan, S. A.; Martinowich, K.; McCann, K. E.; Dougherty, J. D.; Smith, Y.; Beckstead, M. J.; Weinshenker, D.
10.1101/2023.03.07.530845 — neuroscience — Posted on 2024-08-04
4512 Driving forces for condensation of synapsin are governed by sequence-encoded molecular grammars
Hoffmann, C.; Ruff, K. M.; Edu, I.; Kyung Shinn, M.; Tromm, J.; King, M.; Pant, A.; Ausserwoeger, H.; Morgan, J.; Knowles, T.; Pappu, R. V.; Milovanovic, D.
10.1101/2024.08.03.606464 — biochemistry — Posted on 2024-08-04
4514 Endothelial Immunosuppression in Atherosclerosis : Translational Control by Elavl1/HuR
Nicholas, S.-A. E.; Helming, S. R.; Menoret, A.; Pathoulas, C.; Xu, M. M.; Hensel, J.; Kimble, A. L.; Heineman, B.; Jellison, E. R.; Reese, B.; Zhou, B.; Rodriguez-Oquendo, A.; Vella, A. T.; Murphy, P. A.
10.1101/2024.08.02.605922 — cell biology — Posted on 2024-08-04
4515 Phylogeny, morphology, and behavior of the new ciliate species Stentor stipatus
Rajan, D. H.; Lee, B.; Albright, A.; Tang, E. J.; Maravillas, A.; Vargas, C.; Marshall, W. F.; Cortes, D.
10.1101/2024.08.03.606273 — cell biology — Posted on 2024-08-04
4517 CaMKII induces an autophagy-dependent anabolic response in Articular Chondrocytes
Day, N. J.; Dutta, A.; Heluany, C. S.; Asopa, V.; Sochart, D.; Fielding, B.; Nalesso, G.
10.1101/2024.08.04.606243 — cell biology — Posted on 2024-08-04
4520 Distance between miRNA responsive elements selectively enhances target specificity with reduced cellular toxicity by miRNA-mediated synergism
Mazumder, S.; Banerjee, U.; Sinsinwar, S.; Mandal, S.; Prusty, D.; Babele, P.; Das, B.; Manna, S. K.; Ray, J. G.; Chatterjee, R.
10.1101/2024.08.01.606174 — cancer biology — Posted on 2024-08-04
4522 Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus
Zeng, H.; Ai, M.; Zhou, X.; Carrer, M.; Jafar-nejad, P.; Li, Y.; Gades, N. M.; Alexander, M. P.; Bautista, M. A.; Duarte Garcia, A. A.
10.1101/2024.08.01.606069 — immunology — Posted on 2024-08-04
4523 Autosomal Dominant-Hyper-IgE Syndrome patients contain pre-Th17-cells that are activated by opportunistic pathogens to produce IL-10
Moschetti, G.; Vasco, C.; Clemente, F.; Larghi, P.; Maioli, S.; Scarpa, E.; Carelli, E.; Pulvirenti, N.; Sarnicola, M. L.; Crosti, M.; Bel Imam, M.; van de Veen, W.; Rizzello, L.; Abrignani, S.; Baselli, L. A.; Dellepiane, R. M.; Carrabba, M.; Fabio, G.; Geginat, J.
10.1101/2024.08.01.606136 — immunology — Posted on 2024-08-04
4525 Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism
Wu, W.; Yu, M.; Li, Q.; Zhao, Y.; Zhang, L.; Sun, Y.; Wang, Z.; Gong, Y.; Wang, W.; Liu, C.; Zhang, J.; Tang, Y.; Xu, X.; Guo, X.; Zhan, J.; Zhang, H.
10.1101/2024.08.01.606147 — cancer biology — Posted on 2024-08-04
4526 The AP2/ERF transcription factor HcERF5 confers drought tolerance via ABA-mediated signaling in kenaf
Luo, D.; Mubeen, S.; Rehman, M.; Cao, S.; Wang, C.; Yue, J.; Pan, J.; Jin, G.; Li, R.; Chen, T.; Chen, P.
10.1101/2024.08.01.606231 — molecular biology — Posted on 2024-08-04
4527 DREAMER: Exploring Common Mechanisms of Adverse Drug Reactions and Disease Phenotypes through Network-Based Analysis
Firoozbakht, F.; Elkjaer, M. L.; Handy, D.; Wang, R.; Chervontseva, Z.; Rarey, M.; Loscalzo, J.; Baumbach, J.; Tsoy, O.
10.1101/2024.07.20.602911 — systems biology — Posted on 2024-08-04
4533 Towards Stewardship of Wild Species and Their Domesticated Counterparts: A Case Study in Northern Wild Rice (Zizania palustris L.)
McGilp, L.; Haas, M. W.; Shao, M.; Millas, R.; Castell-Miller, C.; Kern, A.; Shannon, L. M.; Kimball, J.
10.1101/2022.08.25.505308 — genetics — Posted on 2024-08-04
4534 Members of an array of zinc finger proteins specify distinct Hox chromatin boundaries
Ortabozkoyun, H.; Huang, P.-Y.; Gonzalez-Buendia, E.; Cho, H.; Kim, S. Y.; Tsirigos, A.; Mazzoni, E. O.; Reinberg, D.
10.1101/2023.04.25.538167 — genetics — Posted on 2024-08-04
4536 Prevalence of errors in lab-made plasmids across the globe
Bai, X.; Hong, J. F.; Yu, S.; Hu, D. Y.; Chen, A. Y.; Rich, C. A.; Shi, S. J.; Xu, S. Y.; Croucher, D. M.; Mussar, K. J.; Meng, D. W.; Chen, J. L.; Lahn, B. T.
10.1101/2024.06.17.596931 — molecular biology — Posted on 2024-08-04
4537 Hexa-acylated lipopolysaccharides from the gut microbiota enhance cancer immunotherapy responses
Beresford-Jones, B. S.; Sardar, P.; Xia, W.; Shabana, O.; Suyama, S.; Ramos, R. J. J. F.; Soderholm, A. T.; Tourlomousis, P.; Kuo, P.; Evans, A. C.; Imianowski, C. J.; Conti, A. G.; Wesolowski, A. J.; Okkenhaug, K.; Whiteside, S. K.; Roychoudhuri, R.; Bryant, C. E.; Cross, J. R.; Pedicord, V. A.
10.1101/2024.06.24.600291 — microbiology — Posted on 2024-08-04
4538 Hierarchical gradients of multiple timescales in the mammalian forebrain
Song, M.; Shin, E. J.; Seo, H.; Soltani, A.; Steinmetz, N. A.; Lee, D.; Jung, M. W.; Paik, S.-B.
10.1101/2023.05.12.540610 — neuroscience — Posted on 2024-08-04
4540 Molecular and cellular dynamics of the developing human neocortex at single-cell resolution
Wang, L.; Wang, C.; Moriano, J. A.; Chen, S.; Zuo, G.; Cebrian-Silla, A.; Zhang, S.; Mukhtar, T.; Wang, S.; Song, M.; de Oliveira, L. G.; Bi, Q.; Augustin, J. J.; Ge, X.; Paredes, M. F.; Huang, E. J.; Alvarez-Buylla, A.; Duan, X.; Li, J.; Kriegstein, A. R.
10.1101/2024.01.16.575956 — neuroscience — Posted on 2024-08-04
4541 Parallel reconstruction of the excitatory and inhibitory inputs received by single neurons reveals the synaptic basis of recurrent spiking
Bartram, J.; Franke, F.; Kumar, S. S.; Buccino, A. P.; Xue, X.; Ganswein, T.; Schroter, M.; Kim, T.; Kasuba, K. C.; Hierlemann, A.
10.1101/2023.01.06.523018 — neuroscience — Posted on 2024-08-04
4542 Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice
Ishchenko, Y.; Jeng, A. T.; Feng, S.; Nottoli, T.; Manriquez-Rodriguez, C.; Nguyen, K.; Carrizales, M. G.; Vitarelli, M. J.; Corcoran, E. E.; Greer, C. A.; Myers, S. A.; Koleske, A. J.
10.1101/2024.01.05.574442 — neuroscience — Posted on 2024-08-04
4547 Conservation of dichromatin organization along regional centromeres
Dubocanin, D.; Hartley, G. A.; Cortes, A. E. S.; Mao, Y.; Hedouin, S.; Ranchalis, J. E.; Agarwal, A.; Logsdon, G.; Munson, K. M.; Real, T. D.; Mallory, B. J.; Eichler, E. E.; Biggins, S.; O'Neill, R. J.; Stergachis, A. B.
10.1101/2023.04.20.537689 — genomics — Posted on 2024-08-04
4550 Disentangling cell-intrinsic and extrinsic factors underlying evolution
Starr, A. L.; Nishimura, T.; Igarashi, K. J.; Funamoto, C.; Nakauchi, H.; Fraser, H.
10.1101/2024.05.06.592777 — evolutionary biology — Posted on 2024-08-04
4552 Seed functional ecology in Brazilian rock outcrop vegetation: an integrative synthesis
Ordonez-Parra, C. A.; Medeiros, N. F.; Dayrell, R. L. C.; Le Stradic, S.; Negreiros, D.; Cornelissen, T.; Silveira, F. A. O.
10.1101/2023.03.21.533674 — ecology — Posted on 2024-08-04
4554 Using machine learning to dissect host kinases required for Leishmania internalization and development
Wei, L.; Barrie, U.; Aloisio, G. M.; Khuong, F. T. H.; Arang, N.; Datta, A.; Kaushansky, A.; Wetzel, D. M.
10.1101/2024.05.16.593986 — microbiology — Posted on 2024-08-04
4555 Nutrient colimitation is a quantitative, dynamic property of microbial populations
Held, N. A.; Krishna, A.; Crippa, D.; Battaje, R. R.; Devaux, A. J.; Dragan, A.; Manhart, M.
10.1101/2023.09.27.559472 — microbiology — Posted on 2024-08-04
4556 Genomic and phenotypic characterization of an Oropouche virus strain implicated in the 2023-24 large-scale outbreak in Brazil
Azevedo, E. A. N.; da Silva, A. F.; da Silva, V. V. G.; Machado, L. C.; de Lima, G. B.; Ishigami, B. I. M.; Silva, K. M. P.; da Costa, M. M. O. M.; Falcao, D. A.; Vasconcelos, A. P.; da Silva, C. C.; Naveca, F. G.; Bezerra, M. F.; Campos, T. L.; Acioli-Santos, B.; Paiva, M. H. S.; Morais, C. N. L.; Wallau, G. d. L.
10.1101/2024.08.02.606252 — microbiology — Posted on 2024-08-04
4558 A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency
Kuhn, B. N.; Cannella, N.; Crow, A.; Lunerti, V.; Gupta, A.; Walterhouse, S.; Allen, C.; Chalhoub, R.; Dereschewitz, E.; Roberts, A.; Cockerham, M.; Beeson, A.; Nall, R.; Palmer, A. A.; Hardiman, G.; Solberg-Woods, L.; Chung, D.; Ciccocioppo, R.; Kalivas, P.
10.1101/2024.02.22.581440 — neuroscience — Posted on 2024-08-04
4560 A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs
Brown, C.; Ghosh, S.; McAllister, R.; Kumar, M.; Walker, G.; Sun, E.; Aman, T.; Panda, A.; Kumar, S.; Li, W. V.; Coleman, J.; Liu, Y.; Rothman, J. E.; Bhattacharyya, M.; Gupta, K.
10.1101/2024.02.10.579775 — biophysics — Posted on 2024-08-04
4563 Concerted modulation of spontaneous behavior and time-integrated whole-brain neuronal activity by serotonin receptors
Friedmann, D.; Gonzalez, X.; Moses, A.; Watts, T.; Degleris, A.; Ticea, N.; Song, J. H.; Datta, S. R.; Linderman, S. W.; Luo, L.
10.1101/2024.08.02.606282 — neuroscience — Posted on 2024-08-03
4565 Bezafibrate treatment rescues neurodevelopmental and neurodegenerative defects in 3D cortical organoid model of MAPT frontotemporal dementia
Cordella, F.; Mautone, L.; Tondo, L.; Salerno, D.; Ghirga, S.; Parente, E.; Romeo, M. A.; Cirone, M.; Bezzi, P.; Di Angelantonio, S.
10.1101/2024.08.02.606317 — neuroscience — Posted on 2024-08-03
4566 Structural perturbation of chromatin domains with multiple developmental regulators can severely impact gene regulation and development
Chakraborty, S.; Wenzlitschke, N.; Anderson, M. J.; Eraso, A.; Baudic, M.; Thompson, J. J.; Evans, A. A.; Shatford Adams, L. M.; Chari, R.; Awasthi, P.; Dale, R. K.; Lewandoski, M.; Petros, T. J.; Rocha, P. P.
10.1101/2024.08.03.606480 — developmental biology — Posted on 2024-08-03
4567 Biophysical Simulation Enables Multi-Scale Segmentation and Atlas Mapping for Top-Down Spatial Omics of the Nervous System
Mohammed Ali, L. K.; Yim, A. K. Y.; Nguyen, T.; Tu, N. K.; Gerbi, E. B.; Grigore, D.; Waligorski, J. E.; Kremitzki, C. L.; Mitra, R. D.; Milbrandt, J. D.; Buchser, W. J.
10.1101/2024.08.02.605366 — neuroscience — Posted on 2024-08-03
4569 A map of integrated cis-regulatory elements enhances gene regulatory analysis in maize
Manosalva Perez, N.; Staut, J.; Matres Ferrando, A.; Dissanayake, I.; Vandepoele, K.
10.1101/2024.08.01.606127 — bioinformatics — Posted on 2024-08-03
4570 Computational design of highly active de novo enzymes
Braun, M.; Tripp, A.; Chakatok, M.; Kaltenbrunner, S.; Totaro, M. G.; Stoll, D.; Bijelic, A.; Elaily, W.; Hoch, S. Y. Y.; Aleotti, M.; Hall, M.; Oberdorfer, G.
10.1101/2024.08.02.606416 — biochemistry — Posted on 2024-08-03
4572 A causative SNP in the promoter of myogenin is essential for myogenic differentiation
Lin, Z.; Wang, X.; Liang, Z.; Xu, R.; Chen, M.; Tong, X.; Li, C.; Xiong, Y.; Yuan, R.; Chen, Y.; Liu, X.; Zhao, Y.; Mo, D.
10.1101/2024.08.01.606143 — genetics — Posted on 2024-08-03
4573 Dose-dependent regulation of immune memory responses against HIV by saponin monophosphoryl lipid A nanoparticle adjuvant
Ramezani-Rad, P.; Marina-Zarate, E.; Maiorino, L.; Myers, A.; Michaels, K. K.; Pires, I. S.; Bloom, N. I.; Lopez, P. G.; Cottrell, C. A.; Burton, I.; Groschel, B.; Pradhan, A.; Stiegler, G.; Budai, M.; Kumar, D.; Pallerla, S.; Sayeed, E.; Sagar, S. L.; Kasturi, S. P.; Van Rompay, K. K. A.; Hangartner, L.; Wagner, A.; Burton, D. R.; Schief, W. R.; Crotty, S.; Irvine, D. J.
10.1101/2024.07.31.604373 — immunology — Posted on 2024-08-03
4574 Neutralization activity in chronic HIV infection is characterized by a distinct programming of follicular helper CD4 T cells
Moysi, E.; Sharma, A. A.; O'Dell, S.; Georgakis, S.; Del Rio Estrada, P. M.; Torres-Ruiz, F.; Gonzalez Navarro, M.; Luna Villalobos, Y. A.; Avila Rios, S.; Reyes-Teran, G.; Beddall, M. H.; Ko, S.-H.; Belinky, F.; Orfanakis, M.; de Leval, L.; Enriquez, A. B.; Buckner, C. M.; Moir, S.; Doria-Rose, N.; Boritz, E.; Mascola, J. R.; Sekaly, R. P.; Koup, R. A.; Petrovas, C.
10.1101/2024.07.31.605954 — immunology — Posted on 2024-08-03
4576 Integration of sensory and fear memories in the rat medial temporal lobe
Wong, F. S.; Thomas, A. B.; Killcross, S.; Laurent, V.; Westbrook, R. F.; Holmes, N. M.
10.1101/2024.07.31.605652 — neuroscience — Posted on 2024-08-03
4577 The assembly of Y chromosome reveals amplification of genes regulating male fertility in Bactrocera dorsalis
Wu, S.; Wu, J.; Lei, Q.; He, D.; Jiang, X.; Ye, C.; Wei, D.; Wang, J.-J.; Xu, L.; Jiang, H.
10.1101/2024.08.01.606120 — zoology — Posted on 2024-08-03
4578 Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states
Southard, K. M.; Ardy, R. C.; Tang, A.; O'Sullivan, D. D.; Metzner, E.; Guruvayurappan, K.; Norman, T. M.
10.1101/2024.07.31.606073 — systems biology — Posted on 2024-08-03
4581 Gene editing of the E3 ligase PIRE1 fine-tunes ROS production for enhanced bacterial disease resistance in tomato
Castro, B.; Baik, S.; Tran, M.; Zhu, J.; Li, T.; Aoun, N.; Blundell, A.; Gomez, M.; Zhang, E.; Cho, M.-J.; Lowe-Power, T.; Siddique, S.; Staskawicz, B.; Coaker, G.
10.1101/2024.07.31.606097 — plant biology — Posted on 2024-08-03
4585 Inhibition of Atrial Natriuretic Peptide Clearance Reduces Myocardial Fibrosis and Improves Cardiac Function in Diabetic Rats
Fares, N.; Bakhos, J. J.; Saliba, Y.; Hajal, J.; Achkouty, G.; Oskaridjian, H.; Azevedo, C.; Semaan, A.; Suffee, N.; Balse, E.; Hatem, S. N.
10.1101/2024.08.01.606125 — physiology — Posted on 2024-08-03
4586 tp53 R217H and R242H Mutant Zebrafish Exhibit Dysfunctional p53 Hallmarks and Recapitulate Li-Fraumeni Syndrome Phenotypes
Kobar, K.; Berman, J. N.; Fiene, J. A.; Tuzi, L.; Burnley, E.; Galpin, K. J. C.; Midgen, C.; Laverty, B.; Moksa, M.; Cao, Q.; Subasri, V.; Wen, T. T.; Shlien, A.; Hirst, M.; Malkin, D.; Prykhozhij, S.; Carles, A.
10.1101/2024.07.31.605368 — cancer biology — Posted on 2024-08-03
4589 Along- and cross-muscle fiber shear moduli in skeletal muscle
Sahani, R.; Reyna, W.; Royston, T.; Perreault, E. J.; Ludvig, D.
10.1101/2024.07.31.605692 — bioengineering — Posted on 2024-08-03
4590 Adapting protein language models for structure-conditioned design
Ruffolo, J. A.; Bhatnagar, A.; Beazer, J.; Nayfach, S.; Russ, J.; Hill, E.; Hussain, R.; Gallagher, J.; Madani, A.
10.1101/2024.08.03.606485 — bioengineering — Posted on 2024-08-03
4592 Distinct microbial communities are linked to organic matter properties in millimetre-sized soil aggregates
Simon, E.; Guseva, K.; Darcy, S.; Alteio, L.; Pjevac, P.; Schmidt, H.; Jenab, K.; Ranits, C.; Kaiser, C.
10.1101/2024.08.01.606122 — ecology — Posted on 2024-08-03
4595 A comprehensive genetic catalog of human double-strand break repair
Lopez de Alba, E.; Salguero, I.; Gimnez-Llorente, D.; Fernandez-Sanroman, A.; Casajus-Pelegay, E.; Terron-Bautista, J.; Barroso-Gonzalez, J.; Bernal, J. A.; Macintyre, G.; Fernandez-Leiro, R.; Losada, A.; Cortes-Ledesma, F.
10.1101/2024.08.03.606369 — molecular biology — Posted on 2024-08-03
4596 Unraveling the Molecular mechanism of Polysaccharide Lyases for Efficient Alginate Degradation
Rivas-Fernandez, J. P.; Vuillemin, M.; Pilgaard, B.; J. Klau, L.; Fredslund, F.; Lund-Hanssen, C.; H. Welner, D.; S. Meyer, A.; Morth, J. P.; Meilleur, F.; L. Aachmann, F.; Rovira, C.; Wilkens, C.
10.1101/2024.08.02.606366 — molecular biology — Posted on 2024-08-03
4598 Landscape of Differentiation Potentials as a "Hallmark" in Oral-derived MSCs
Chopra, H.; Cao, C.; Herrmann, A.; Kak, S.; Maska, B.; Tagett, R.; Garmire, L.; Sugai, J.; Kaigler, D.
10.1101/2024.08.02.606413 — molecular biology — Posted on 2024-08-03
4602 The study on the impact of indoleacetic acid on enhancing the ability of the rumen's original microecology to degrade aflatoxin B1.
Guo, G.; Sun, J.; wang, z.; Yan, X.; Zhao, Y.; Tan, L.; Miao, X.; Zhao, R.; Huo, W.; Chen, L.; Li, Q.; Liu, Q.; Wang, C.
10.1101/2024.08.02.606440 — microbiology — Posted on 2024-08-03
4603 A targeted CRISPR screen identifies ETS1 as a regulator of HIV latency.
Ashokkumar, M.; Hafer, T. L.; Felton, A.; Archin, N.; Margolis, D. M.; Emerman, M.; Browne, E. P.
10.1101/2024.08.03.606477 — microbiology — Posted on 2024-08-03
4604 Gut Microbiome Perturbation Affected Conjugative Transfer of Antimicrobial Resistance Genes
Yilmaz, G.; Chan, M.; Lau, C. H.-F.; Capitani, S.; Kang, M.; Charron, P.; Hoover, E.; Topp, E.; Guan, J.
10.1101/2024.08.03.605226 — microbiology — Posted on 2024-08-03
4605 An engineered prodrug selectively suppresses β-lactam resistant bacteria in a mixed microbial setting
Duda, A. M.; Ma, H. R.; Villalobos, C. A.; Kuhn, S. A.; He, K.; Seay, S. R.; Jackson, A. C.; Suh, C. M.; Puccio, E. A.; Anderson, D. A.; Fowler, V. G.; You, L.; Franz, K. J.
10.1101/2024.08.02.606422 — microbiology — Posted on 2024-08-03
4610 Modeling glioblastoma tumor progression via CRISPR-engineered brain organoids
Ishahak, M.; Han, R. H.; Annamalai, D.; Woodiwiss, T.; McCornack, C.; Cleary, R. T.; DeSouza, P. A.; Qu, X.; Dahiya, S.; Kim, A. H.; Millman, J. R.
10.1101/2024.08.02.606387 — bioengineering — Posted on 2024-08-03
4619 A microglia clonal inflammatory disorder in Alzheimer's Disease
Vicario, R.; Fragkogianni, S.; Weber, L.; Lazarov, T.; Hu, Y.; Hayashi, S. Y.; Craddock, B. P.; Socci, N. D.; Alberdi, A.; Baako, A.; Ay, O.; Ogishi, M.; Lopez-Rodrigo, E.; Kappagantula, R.; Viale, A.; Iacobuzio-Donahue, C. A.; Zhou, T.; Ransohoff, R. M.; Chesworth, R.; Netherlands Brain Bank, ; Abdel-Wahab, O.; Boisson, B.; Elemento, O.; Casanova, J.-L.; Miller, W. T.; Geissmann, F.
10.1101/2024.01.25.577216 — neuroscience — Posted on 2024-08-03
4621 Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer
Su, Y.; Liu, C.; Lu, X.; Li, G.; Shao, S.; Kong, Y.; Lee, J.; Ng, R.; Wong, S.; Robert, L.; Warden, C.; Liu, V.; Chen, J.; Wang, Z.; Qin, G.; Tang, Y.; Cheng, H.; Ng, A.; Peng, S.; Xue, M.; Johnson, D.; Xu, Y.; Wang, J.; Wu, X.; Shmulevich, I.; Shi, Q.; Levine, R.; Ribas, A.; Baltimore, D.; Guo, J.; Heath, J. R.; Wei, W.
10.1101/724740 — cancer biology — Posted on 2024-08-03
4624 An EYA3/NF-κB/CCL2 signaling axis suppresses cytotoxic NK cells in the pre-metastatic niche to promote triple negative breast cancer metastasis
Rosenbaum, S. R.; Hughes, C. J.; Fields, K. M.; Purdy, S. C.; Gustafson, A.; Wolin, A.; Hampton, D.; Turner, N.; Ebmeier, C. C.; Costello, J. C.; Ford, H. L.
10.1101/2024.07.31.606072 — cancer biology — Posted on 2024-08-03
4625 Activated Interferon Signaling Suppresses Age-Dependent Liver Cancer
Havas, A.; Lande, K.; Rajesh, A.; Evensen, K. G.; Varanasi, S. K.; Shang, L.; Schmidt, E.; Lee, J.; Kim, K.; Teneche, M. G.; Hoffmann, F.; LaPorte, M.; Davis, A.; Grier, A.; Reisz, J. A.; Tharp, K.; Gandhi, A.; Lei, X.; Proulx, J.; Miller, K. N.; Sacco, A.; Shadel, G. S.; Niedernhofer, L.; Feng, G.-S.; D'Alesssandro, A.; Kaech, S.; Williams, A.; Adams, P. D.
10.1101/2024.07.31.606057 — cancer biology — Posted on 2024-08-03
4626 PAX fusion proteins deregulate gene networks controlling mitochondrial translation in pediatric rhabdomyosarcoma
Kalita, B.; Martinez-Cebrian, G.; McEvoy, J.; Allensworth, M.; Knight, M.; Magli, A.; Perlingeiro, R. C. R.; Dyer, M. A.; Stewart, E. A.; Dynlacht, B. D.
10.1101/2024.07.31.606039 — cancer biology — Posted on 2024-08-03
4627 Bootstrap Evaluation of Association Matrices (BEAM) for Integrating Multiple Omics Profiles with Multiple Outcomes
Seffernick, A. E.; Cao, X.; Cheng, C.; Yang, W.; Autry, R. J.; Yang, J. J.; Pui, C.-H.; Teachey, D. T.; Lamba, J. K.; Mullighan, C. G.; Pounds, S. B.
10.1101/2024.07.31.605805 — bioinformatics — Posted on 2024-08-03
4628 Predatory aggression evolved through adaptations to noradrenergic circuits
Eren, G. G.; Boger, L.; Roca, M.; Hiramatsu, F.; Liu, J.; Alvarez, L.; Goetting, D. L.; Zorn, N.; Han, Z.; Okumura, M.; Scholz, M.; Lightfoot, J. W.
10.1101/2024.08.02.606321 — animal behavior and cognition — Posted on 2024-08-02
4629 Effects of short-term isolation on vocal and non-vocal social behaviors in prairie voles
Madrid, J. E.; Pranic, N. M.; Chu, S.; Bergstrom, J. J. D.; Singh, R.; Rabinovich, J.; Lopez, K. A.; Ophir, A. G.; Tschida, K. A.
10.1101/2024.08.02.605822 — animal behavior and cognition — Posted on 2024-08-02
4631 Uncovering Individualized Cerebellar Atrophy Pattern and Behavioral Links in Children with Brainstem Tumor
Jia, H.; Wang, K.; Zhang, M.; Gu, G.; Mai, Y.; Wu, X.; Chu, C.; Yin, X.; Zhang, P.; Fan, L.; Zhang, L.
10.1101/2024.08.01.606261 — neuroscience — Posted on 2024-08-02
4632 Co-activation of LIN28A and CTNNB1 disturbs cortical neuronal migration and pia mater integrity
Navolic, J.; Hawass, S.; Moritz, M.; Hahn, J.; Middelkamp, M.; Gocke, A.; Dottermusch, M.; Schumann, Y.; Ruck, L.; Krisp, C.; Godbole, S.; Sumislawski, P.; Schlueter, H.; Neumann, J. E.
10.1101/2024.08.01.606182 — neuroscience — Posted on 2024-08-02
4634 Word-selective EEG/MEG responses in the English language obtained with Fast Periodic Visual Stimulation (FPVS)
Hauk, O.; Marchive, M.; Volfart, A.; Schiltz, C.; Rossion, B.; Lambon Ralph, M. A.; Lochy, A.
10.1101/2024.08.02.606349 — neuroscience — Posted on 2024-08-02
4635 A modified dual preparatory method for improved isolation of nucleic acids from laser microdissected fresh-frozen human cancer tissue specimens
Kimble, D. C.; Litzi, T. J.; Snyder, G.; Olowu, V.; TaQee, S.; Conrads, K. A.; Loffredo, J.; Bateman, N. W.; Alba, C.; Rice, E.; Shriver, C. D.; Maxwell, G. L.; Dalgard, C.; Conrads, T. P.
10.1101/2024.08.02.606193 — biochemistry — Posted on 2024-08-02
4636 Biased estimates of phylogenetic branch lengths resulting from the discretised Gamma model of site rate heterogeneity
Ferretti, L.; Golubchik, T.; Di Lauro, F.; Ghafari, M.; Villabona-Arenas, J.; Atkins, K. E.; Fraser, C.; Hall, M. D.
10.1101/2024.08.01.606208 — evolutionary biology — Posted on 2024-08-02
4640 Targeting of retrovirus-derived Rtl8a/8b reduces social response and increases apathy-like behavior associated with GABRB2 reduction
Fujioka, Y.; Shiura, H.; Ishii, M.; Ono, R.; Endo, T.; Kiyonari, H.; Hirate, Y.; Ito, H.; Azuma-Kanai, M.; Kohda, T.; Kaneko-Ishino, T.; Ishino, F.
10.1101/2024.08.02.606341 — molecular biology — Posted on 2024-08-02
4641 Genomic and phenotypic characterization of an Oropouche virus strain implicated in the 2023-24 large-scale outbreak in Brazil
Azevedo, E. A. N.; da Silva, A. F.; da Silva, V. V. G.; Machado, L. C.; de Lima, G. B.; Silva, K. M. P.; da Costa, M. M. O. M.; Falcao, D. A.; Vasconcelos, A. P.; da Silva, C. C.; Naveca, F. G.; Bezerra, M. F.; Campos, T. L.; Acioli-Santos, B.; Paiva, M. H. S.; Morais, C. N. L.; Wallau, G. d. L.
10.1101/2024.08.02.606252 — microbiology — Posted on 2024-08-02
4643 Dysbiosis-associated gut bacterium Ruminococcus gnavus varies at the strain level in ability to utilize key mucin component sialic acid
Sokolovskaya, O. M.; Uzunovic, J.; Peng, Y.; Okumura, M.; Wang, L. M.; Zhou, Y.; Lai, Z.; Skippington, E.; Tan, M.-W.
10.1101/2024.08.02.604340 — microbiology — Posted on 2024-08-02
4646 Cross-feeding options define eco-evolutionary dynamics of deep oligotrophic groundwater microbiome
Rezaei Somee, M.; Gonzalez-Rosales, C.; Gralka, M.; Turner, S.; Bertilsson, S.; Dopson, M.; Mehrshad, M.
10.1101/2024.08.02.606368 — microbiology — Posted on 2024-08-02
4647 Roles of PknB and CslA in cell wall morphogenesis of Streptomyces
Derkacz, M.; Watson, A.; Gajbhiye, A.; Jakimowicz, D.; Trost, M.; Errington, J.; Kepplinger, B.
10.1101/2024.08.02.606377 — microbiology — Posted on 2024-08-02
4649 WITHDRAWN: Mechanistic modelling of Mycobacterium Tuberculosis beta carbonic anhydrase 3 inhibitors
Manaithiya, A.; Bhowmik, R.; Ray, R.; Carta, F.; Supuran, C. T.; Parkkila, S.; Aspatwar, A.
10.1101/2024.04.30.591915 — bioinformatics — Posted on 2024-08-02
4650 Thermodynamic modeling of Csr/Rsm- RNA interactions capture novel, direct binding interactions across the Pseudomonas aeruginosa transcriptome
Lukasiewicz, A. J.; Leistra, A. N.; Hoefner, L.; Monzon, E.; Gode, C. J.; Zorn, B. T.; Janssen, K. H.; Yahr, T. L.; Wolfgang, M. C.; Contreras, L. M.
10.1101/2024.08.01.606018 — bioinformatics — Posted on 2024-08-02
4652 The phage protein paratox is a multifunctional metabolic regulator of Streptococcus
Muna, T. H.; Rutbeek, N. R.; Horne, J.; Lao, Y. W.; Krokhin, O. V.; Prehna, G.
10.1101/2024.08.02.605684 — biochemistry — Posted on 2024-08-02
4653 Ordering molecular diversity in untargeted metabolomics via molecular community networking
Coler, E. A.; Melnik, A.; Lotfi, A.; Moradi, D.; Ahiadu, B.; Portal Gomes, P. W.; Patan, A.; Dorrestein, P. C.; Barnes, S.; Boginski, V.; Semenov, A.; Aksenov, A. A.
10.1101/2024.08.02.606356 — biochemistry — Posted on 2024-08-02
4655 The Streptococcus agalactiae LytSR two-component regulatory system promotes vaginal colonisation and virulence in vivo
AlQadeeb, H.; Baltazar, M.; Cazares, A.; Poonpanichakul, T.; Kjos, M.; French, N.; Kadioglu, A.; O'Brien, M.
10.1101/2024.08.02.606384 — microbiology — Posted on 2024-08-02
4656 Endocytic dynamin deficiency impairs the host colonization of phytopathogenic fungi
Chen, X.; Chen, X.; Long, Y.; Fang, Z.; Abubakar, Y. S.; Zheng, H.; Wang, Z.; Zheng, W.
10.1101/2024.08.02.606287 — microbiology — Posted on 2024-08-02
4657 A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole of Chlamydia trachomatis
Babu Sait, M. R.; Jachmann, L. H.; Milivojevic, M.; Llorente-Saez, C.; Dhanjal, S.; Schumacher, F.; Henriksson, S.; Gayathri Vegesna, N. V.; Chaban, A.; Mohanty, P.; Ölander, M.; Muraleedharan, S.; Farmand Azadeh, S.; Kleuser, B.; Schmierer, B.; Sixt, B. S.
10.1101/2024.08.02.606337 — microbiology — Posted on 2024-08-02
4658 Impact of commercial gut health interventions on caecal metagenome and broiler performance
Pangga, G. M. V.; Star-Shirko, B.; Psifidi, A.; Xia, D.; Corcionivoschi, N.; Kelly, C.; Hughes, C.; Lavery, U.; Richmond, A.; Ijaz, U. Z.; Gundogdu, O.
10.1101/2024.08.02.606333 — microbiology — Posted on 2024-08-02
4660 Recycling of trans-Golgi SNAREs is essential for apoplastic effector secretion and effective pathogenicity of Magnaporthe oryzae
Lin, L.; Wu, Q.; Wang, S.; Gong, Q.; Huang, X.; Abubakar, Y. S.; Liu, Y.; Cao, J.; Hu, J.; Wang, Z.; Lu, G.; Zheng, W.
10.1101/2024.08.02.606313 — microbiology — Posted on 2024-08-02
4662 Using virtual patient cohorts to uncover immune response differences in cancer and immunosuppressed COVID-19 patients
Gazeau, S.; Deng, X.; Brunet-Ratnasingham, E.; Kaufmann, D. E.; Larochelle, C.; Morel, P. A.; Heffernan, J. M.; Davis, C. L.; Smith, A. M.; Jenner, A. L.; Craig, M.
10.1101/2024.08.01.605860 — immunology — Posted on 2024-08-02
4665 Nanopore-based analysis unravels the genetic landscape and phylogenetic placement of human-infecting Trichuris species in Cote d'Ivoire, Tanzania, Uganda, and Laos
Rahman, N.; Bär, M. A.; Dommann, J.; Hürlimann, E.; Coulibaly, J. T.; Ali, S.; Sayasone, S.; Beinamaryo, P.; Keiser, J.; Schneeberger, P. H. H.
10.1101/2024.07.31.605962 — genomics — Posted on 2024-08-02
4666 Genetic diversity and antimicrobial resistance of Campylobacter jejuni isolates from Gambian children under five with moderate-to-severe diarrhoea and healthy Controls
Betts, M.; Dione, M.; Ikumapayi, U. N.; Senghore, M.; Lamin, M.; Foster-Nyarko, E.; Jaffali, J.; Panchalingam, S.; Nataro, J. P.; Kotloff, K. L.; Levine, M. M.; Saha, D.; Hossain, J. M.; Kwambana-Adams, B.; Antonio, M.
10.1101/2024.07.30.605890 — microbiology — Posted on 2024-08-02
4667 Bovine H5N1 influenza virus binds poorly to human-type sialic acid receptors
Santos, J. J. S.; Wang, S.; McBride, R.; Zhao, Y.; Paulson, J. C.; Hensley, S. E.
10.1101/2024.08.01.606177 — microbiology — Posted on 2024-08-02
4670 Resveratrol targets G-quadruplexes to exert its pharmacological effects
Soriano-Lerma, A.; Sanchez-Martin, V.; Murciano-Calles, J.; Ortiz-Gonzalez, M.; Tello-Lopez, M. J.; Perez-Carrasco, V.; Linde-Rodriguez, A.; Ramirez-Macias, I.; Gomez-Pinto, I.; Lopez-Aliaga, I.; Soriano, M.; Garcia-Salcedo, J. A.
10.1101/2024.07.29.605564 — physiology — Posted on 2024-08-02
4671 Development and application of species ID and insecticide resistance assays, for monitoring sand fly Leishmania vectors in the Mediterranean basin and in the Middle East
Balaska, S.; Khajehali, J.; Mavridis, K.; Akiner, M.; Papapostolou, K. M.; Remadi, L.; Kioulos, I.; Miaoulis, M.; Fotakis, E. A.; Chaskopoulou, A.; Vontas, J.
10.1101/2024.07.30.605769 — pharmacology and toxicology — Posted on 2024-08-02
4672 Integrative analysis of patient-derived tumoroids and ex vivo organoid modeling of ARID1A loss in bladder cancer reveals therapeutic molecular targets
Scholtes, M. P.; Akbarzadeh, M.; Nakauma-Gonzales, J. A.; Galaras, A.; Bazrafshan, A.; Torenvliet, B.; Beikmohammadi, L.; Lozovanu, V.; Romal, S.; Moulos, P.; Kan, T. W.; Algoe, M.; van Royen, M. E.; Sachetti, A.; van den Bosch, T. P. P.; Eussen, B.; de Klein, A.; van Leenders, G. J. L. H.; Boormans, J. L.; Hatzis, P.; Palstra, R.-J.; Zuiverloon, T. C. M.; Mahmoudi, T.
10.1101/2024.07.29.601702 — cancer biology — Posted on 2024-08-02
4678 Perceived and observed biases within scientific communities: a case study in movement ecology
Shaw, A. K.; Fouda, L.; Mezzini, S.; Kim, D.; Chatterjee, N.; Wolfson, D.; Abrahms, B.; Attias, N.; Beardsworth, C. E.; Beltran, R.; Binning, S. A.; Blincow, K. M.; Chan, Y.-C.; Fronhofer, E. A.; Hegemann, A.; Hurme, E. R.; Iannarilli, F.; Kellner, J. B.; McCoy, K. D.; Rafiq, K.; Saastamoinen, M.; Sequeira, A. M. M.; Serota, M. W.; Sumasgutner, P.; Tao, Y.; Torstenson, M.; Yanco, S. W.; Beck, K. B.; Bertram, M. G.; Beumer, L. T.; Bradaric, M.; Clermont, J.; Ellis-Soto, D.; Faltusova, M.; Fieberg, J.; Hall, R. J.; Kolzsch, A.; Lai, S.; Lee-Cruz, L.; Loretto, M.-C.; Loveridge, A.; Michelangeli,
10.1101/2024.07.29.605602 — ecology — Posted on 2024-08-02
4679 Identification of Disease-relevant, Sex-based Proteomic Differences in iPSC-derived Vascular Smooth Muscle
Ariyasinghe, N. R.; Gupta, D.; Escopete, S.; Stotland, A. B.; Sundararaman, N.; Ngu, B.; Dabke, K.; Rai, D.; McCarthy, L.; de Souza Santos, R.; McCain, M. L.; Sareen, D.; Parker, S. J.
10.1101/2024.07.30.605659 — molecular biology — Posted on 2024-08-02
4681 First Report of Nipah virus shed in urine by fruit bats (Pteropus medius), Sri Lanka
Kohl, C.; Siriwardana, S.; Muzeniek, T.; Perera, T.; Bas, D.; Oeruc, M.; Brinkmann, A.; Becker-Ziaja, B.; Schwarz, F.; Jeevatharan, H.; Weerasena, J.; Hadunnetti, S.; Perera, I.; Premawansa, G.; Premawansa, S.; Yapa, W.; Nitsche, A.
10.1101/2024.07.31.605971 — microbiology — Posted on 2024-08-02
4687 Accelerated enzyme engineering by machine-learning guided cell-free expression
Landwehr, G. M.; Bogart, J. W.; Magalhaes, C.; Hammarlund, E.; Karim, A. S.; Jewett, M. C.
10.1101/2024.07.30.605672 — synthetic biology — Posted on 2024-08-02
4689 An updated and expanded characterization of the biological sciences academic job market
Flynn, B.; Kozik, A. J.; Cheng, Y.; Haagan, A. K.; Ng, J.; Smith, C.; Haage, A.; Jadavji, N. M.
10.1101/2024.07.31.606033 — scientific communication and education — Posted on 2024-08-02
4693 Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer
Fercoq, F.; Cairns, G. S.; De Donatis, M.; Mackey, J. B.; Floerchinger, A.; McFarlane, A. J.; Raffo-Iraolagoitia, X. L.; Whyte, D.; Arnott, L. W.; Nixon, C.; Wiesheu, R.; Brown, L.; Al-Khalidi, S.; Norman, J. C.; Roberts, E. W.; Blyth, K.; Coffelt, S. B.; Carlin, L. M.
10.1101/2024.03.19.585724 — immunology — Posted on 2024-08-02
4695 Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells.
Krawczynska, N.; Wang, Y.; Lim, K.; Das Gupta, A.; Lenczowski, A.; Abughazaleh, M.; Bendre, S. V.; Kockaya, L. I.; Schane, C. P.; Fei, Y.; Hernandez, A. G.; Drnevich, J.; Chan, J.; Dobrucki, L. W.; Boppart, M. D.; Ostrander, J. H.; Nelson, E. R. R.
10.1101/2024.08.02.606061 — cancer biology — Posted on 2024-08-02
4696 Insights into Therapeutic Discovery Through the Kelch Domain Structure of Keap1 at Ambient Temperature
Yilmaz, M.; Sever, B.; Kutlu, Y.; Gul, M.; Okuducu, C.; Tavli, S.; Otsuka, M.; Fujita, M.; Haliloglu, T.; Ciftci, H.; DeMirci, H.
10.1101/2024.07.30.605796 — biophysics — Posted on 2024-08-02
4698 SaprotHub: Making Protein Modeling Accessible to All Biologists
Su, J.; Li, Z.; Han, C.; Zhou, Y.; He, Y.; Shan, J.; Zhou, X.; Chang, X.; Ma, D.; OPMC, T.; Steinegger, M.; Ovchinnikov, S.; Yuan, F.
10.1101/2024.05.24.595648 — bioinformatics — Posted on 2024-08-02
4700 WITHDRAWN: Mechanistic modeling of Mycobacterium tuberculosis β-carbonic anhydrase inhibitors using integrated systems biology and the QSAR approach
Bhowmik, R.; Manaithiya, A.; Parkkinen, J.; Kumar, S.; Mathew, B.; Parikka, M.; Carta, F.; Supuran, C. T.; Parkkila, S.; Aspatwar, A.
10.1101/2024.05.07.592909 — bioinformatics — Posted on 2024-08-02
4704 WITHDRAWN: Physiological modeling into the metaverse of Mycobacterium Tuberculosis Beta CA inhibition mechanism
GiovannuzzI, S.; Shyamal, S. S.; Bhowmik, R.; Ray, R.; Manaithiya, A.; Carta, F.; Parkkila, S.; Aspatwar, A.; Supuran, C. T.
10.1101/2024.05.26.595948 — bioinformatics — Posted on 2024-08-02
4713 Not only ClpC1 but also ClpX are drug targets of Ilamycins
Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Li, J.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.
10.1101/2024.02.24.581832 — microbiology — Posted on 2024-08-02
4715 Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation
Lu, J.; Zhang, J.; Jiang, H.; Hu, Z.; Zhang, Y.; He, L.; Yang, J.; Xie, Y.; Wu, D.; Li, H.; Zeng, K.; Tan, P.; Xiao, Q.; Song, Z.; Pan, C.; Bai, X.; Yu, X.
10.1101/2023.03.30.534894 — immunology — Posted on 2024-08-02
4716 Specific pre-plasma cell states and local proliferation at the dark zone - medulla interface characterize germinal center-derived plasma cell differentiation in lymph node
Binet, L.; Dong, C.; Attaf, N.; Gil, L.; Fallet, M.; Boudier, T.; Escaliere, B.; Chasson, L.; Siret, C.; van de Pavert, S. A.; Navarro, J.-M.; Milpied, P.
10.1101/2024.07.26.605240 — immunology — Posted on 2024-08-02
4717 Regulatory T-cells in multiple sclerosis are activated by Epstein-Barr Virus and produce IL-10 in the central nervous system
Pulvirenti, N.; Righetti, C.; Clemente, F.; Serafini, B.; Pietroboni, A.; Galeota, E.; Rosicarelli, B.; Cordiglieri, C.; Iannone, C.; de Riz, M.; Vasco, C.; Espadas de Arias, A.; De Feo, T.; Valenti, L.; Prati, D.; Abrignani, S.; Gerosa, M.; Caporali, R.; Galimberti, D.; Scarpini, E.; Geginat, J.
10.1101/2024.07.30.605745 — immunology — Posted on 2024-08-02
4719 Key determinants of the dual clamp/activator function of Complexin
Makke, M.; Pastor-Ruiz, A.; Yarzagaray, A.; Gaya, S.; Zimmer, M.; Frisch, W.; Bruns, D.
10.1101/2023.10.03.560784 — neuroscience — Posted on 2024-08-02
4720 Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons
Shore, A. N.; Li, K.; Safari, M.; Qunies, A. M.; Spitznagel, B. D.; Weaver, C. D.; Emmitte, K.; Frankel, W.; Weston, M. C.
10.1101/2023.10.11.561953 — neuroscience — Posted on 2024-08-02
4721 DySCo: a general framework for dynamic Functional Connectivity
de Alteriis, G.; Sherwood, O.; Ciaramella, A.; Leech, R.; Cabral, J.; Turkheimer, F. E.; Expert, P.
10.1101/2024.06.12.598743 — neuroscience — Posted on 2024-08-02
4723 The NeuroML ecosystem for standardized multi-scale modeling in neuroscience
Sinha, A.; Gleeson, P.; Marin, B.; Dura-Bernal, S.; Panagiotou, S.; Crook, S.; Cantarelli, M.; Cannon, R. C.; Davison, A. P.; Gurnani, H.; Silver, R. A.
10.1101/2023.12.07.570537 — neuroscience — Posted on 2024-08-02
4724 Impact of aging on the GABAB receptor-mediated connectome
Vasquez, E.; Oresti, G. M.; Paez, M. D.; Callegari, E. A.; Masone, D.; Munoz, E. M.
10.1101/2024.07.31.606013 — neuroscience — Posted on 2024-08-02
4725 HSV-1 infection induces a downstream-shift of the +1 nucleosome
Weiss, E.; Whisnant, A. W.; Hennig, T.; Djakovic, L.; Doelken, L.; Friedel, C. C.
10.1101/2024.03.06.583707 — bioinformatics — Posted on 2024-08-02
4728 The RND efflux pump EefABC is highly conserved within lineages of E. coli commonly associated with infection.
Pugh, H.; Darby, E.; Burgess, L.; Colclough, A.; Meosa-John, A.-R.; Dunn, S.; Connor, C.; Perry, E.; McNally, A.; Bavro, V.; Blair, J. M. A.
10.1101/2024.08.01.606150 — microbiology — Posted on 2024-08-02
4731 Endocytosis of the plasma membrane carboxylate transporter Jen1 in Saccharomyces cerevisiae under alkali stress: a mechanism for preventing loss of essential metabolites
Barata-Antunes, C.; de Hulster, E.; Cardoso, C.; Ribeiro, I. P.; Fernandes, V.; Leite, B.; Casal, M.; Geros, H.; Pronk, J.; Arino, J.; Mans, R.; Paiva, S.
10.1101/2024.08.01.606176 — microbiology — Posted on 2024-08-02
4733 Complement C3d enables protective immunity capable of distinguishing spontaneously transformed from non-transformed cells
Platt, J. L.; Zhao, C.; Chicca, J.; Pianko, M.; Han, J.; The, S.; Rao, A.; Keller, E.; Barbosa, M. G. d. M.; Naing, L.; Pasieka-Axenov, T.; Axenov, L.; schaefer, S.; Farkash, E.; Cascalho, M.
10.1101/2024.07.31.606044 — immunology — Posted on 2024-08-02
4734 Salidroside Mitigates Malignant Arrhythmias by Restoring Sodium Channel Function During Ultra-Acute Myocardial Infarction
Wang, G.; Zhao, Y.; Zhang, C.; Dong, X.; Sun, S.; Wang, X.; Li, D.; Li, X.; Li, H.; Lu, C.-J.; Du, Y.; Chen, Z.; Lin, F.; Hao, G.
10.1101/2024.07.31.606101 — pharmacology and toxicology — Posted on 2024-08-02
4735 PROSER1 Modulates DNA Demethylation through Dual Mechanisms to Prevent Syndromic Developmental Malformations
Fleming, A.; Knatko, E. V.; Li, X.; Zoch, A.; Heckhausen, Z.; Stransky, S.; Brenes, A. J.; Sidoli, S.; Hajkova, P.; O'Carroll, D.; Rasmussen, K. D.
10.1101/2024.07.31.606086 — developmental biology — Posted on 2024-08-02
4738 Toward De Novo Protein Design from Natural Language
Dai, F.; Fan, Y.; Su, J.; Wang, C.; Han, C.; Zhou, X.; Liu, J.; Qian, H.; Wang, S.; Zeng, A.; Wang, Y.; Yuan, F.
10.1101/2024.08.01.606258 — bioengineering — Posted on 2024-08-02
4739 Pollen Partners: The Symbiotic Microbes of Pinus radiata Pollen
Armstrong, C.; Ganasamurthy, S.; Walker, K.; Mercier, C.; Wakelin, S. A.
10.1101/2024.07.31.606094 — ecology — Posted on 2024-08-02
4751 Engineered NKG2C+ NK-like T cells exhibit superior antitumor efficacy while mitigating cytokine release syndrome
Lupo, K. B.; Panjwani, M. K.; Shahid, S.; Sottile, R.; Lawry, C.; Kolk, G.; Kontopolous, T.; Daniyan, A. F.; Chandran, S. S.; Klebanoff, C. A.; Hsu, K. C.
10.1101/2024.07.16.603785 — immunology — Posted on 2024-08-02
4754 Feminization of the precarious at the UNAM: examining obstacles to gender equality
ciccia, l.; Espinosa Lugo, G.; Garcia Guzman, G.; Gasca-Pineda, J.; Velez, P.; Espinosa Asuar, L.
10.1101/2024.05.13.593992 — scientific communication and education — Posted on 2024-08-02
4755 Fibroblast Stromal Support Model for Predicting Human Papillomavirus-Associated Cancer Drug Responses.
James, C. D.; Lewis, R. L.; Fakunmoju, A. L.; Witt, A.; Youssef, A. H.; Wang, X.; Rais, N. M.; Tadimari Prabhakar, A.; Machado, J. M.; Otoa, R.; Bristol, M. L.
10.1101/2024.04.09.588680 — cancer biology — Posted on 2024-08-02
4757 Dynamic in vivo mapping of the methylproteome using a chemoenzymatic approach
Farhi, J.; Emenike, B.; Beusch, C. M.; Lee, R. S.; Jones, R. B.; Verma, A. K.; Jones, C. Y.; Foroozani, M.; Reeves, M.; Sad, K.; Parwani, K. K.; Bagchi, P.; Deal, R.; Katz, D. J.; Corbett, A. H.; Gordon, D. E.; Raj, M.; Spangle, J.
10.1101/2022.07.22.501130 — biochemistry — Posted on 2024-08-01
4761 Protein degradation shapes developmental tempo in mouse and human neural progenitors
Nakanoh, S.; Stamataki, D.; Garcia-Perez, L.; Azzi, C.; Carr, H. L.; Pokhilko, A.; Howell, S.; Yu, L.; Skehel, M.; Oxley, D.; Andrews, S.; Briscoe, J.; Rayon, T.
10.1101/2024.08.01.604391 — developmental biology — Posted on 2024-08-01
4762 Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping.
Foran, G.; Hallam, R. D.; Megaly, M.; Turgambayeva, A.; Antfolk, D.; Li, Y.; Luca, V. C.; Necakov, A.
10.1101/2023.03.17.533124 — cell biology — Posted on 2024-08-01
4763 A Multiplexed SEC-MS Approach to Systematically Study the Interplay Between Protein Assembly-States and Phosphorylation Events
Doron-Mandel, E.; Bokor, B. J.; Ma, Y.; Street, L. A.; Tang, L. C.; Abdou, A. A.; Shah, N. H.; Rosenberger, G.; Jovanovic, M.
10.1101/2023.01.12.523793 — molecular biology — Posted on 2024-08-01
4765 Behavioral Imitation with Artificial Neural Networks Leads to Personalized Models of Brain Dynamics During Videogame Play
Kemtur, A.; Paugam, F.; Pinsard, B.; harel, Y.; Sainath, P.; Clei, M. L.; Boyle, J.; jerbi, K.; Bellec, P.
10.1101/2023.10.28.564546 — neuroscience — Posted on 2024-08-01
4768 Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets
Sibener, L. J.; Mosberger, A. C.; Chen, T. X.; Athalye, V. R.; Murray, J. M.; Costa, R. M.
10.1101/2023.09.20.558560 — neuroscience — Posted on 2024-08-01
4769 "Magnetic Sand" : Illusions of Interactivity
Shimojo, S.; Shimojo, K.; Shimojo, E.; Zheng, S.; Wu, D.-A.
10.1101/2024.07.03.598775 — neuroscience — Posted on 2024-08-01
4771 Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis
Ahanger, S. H.; Zhang, C.; Semenza, E. R.; Gil, E.; Cole, M. A.; Wang, L.; Kriegstein, A. R.; Lim, D.
10.1101/2024.08.01.606248 — neuroscience — Posted on 2024-08-02
4772 Annexin and calcium-regulated priming of legume root cells for endosymbiotic infection
Guillory, A.; Fournier, J.; Kelner, A.; Hobecker, K.; Auriac, M.-C.; Frances, L.; Delers, A.; Pedinotti, L.; Le Ru, A.; Keller, J.; Delaux, P.-M.; Gutjahr, C.; Frei Dit Frey, N.; de Carvalho-Niebel, F.
10.1101/2024.01.10.574854 — plant biology — Posted on 2024-08-01
4774 Disordered proteins interact with the chemical environment to tune their protective function during drying
KC, S.; Nguyen, K. H.; Nicholson, V.; Walgren, A.; Trent, T.; Gollub, E.; Ramero, S.; Holehouse, A. S.; Sukenik, S.; Boothby, T. C.
10.1101/2024.02.28.582506 — biochemistry — Posted on 2024-08-01
4780 The gut microbiota-immune-brain axis in a wild vertebrate: dynamic interactions and health impacts
Pereira, H.; Hoffman, J. I.; Kruger, O.; Czirjak, G. A.; Rinaud, T.; Ottensmann, M.; Gladow, K.-P.; Caspers, B. A.; Maraci, O.; Kaiser, S.; Chakarov, N.
10.1101/2024.08.01.605092 — microbiology — Posted on 2024-08-01
4781 Morphology-dependent entry kinetics and spread of influenza A virus
Peterl, S.; Lahr, C. M.; Schneider, C. N.; Meyer, J.; Podlipensky, X.; Lechner, V.; Villiou, M.; Eis, L.; Klein, S.; Funaya, C.; Cavalcanti-Adam, E. A.; Graw, F.; Selhuber-Unkel, C.; Rohr, K.; Chlanda, P.
10.1101/2024.08.01.605992 — microbiology — Posted on 2024-08-01
4782 Cellular N-myristoyl transferases Are Required for Mammarenavirus Multiplication
Witwit, H.; Betancourt, C.; Cubitt, B.; Khafaji, R.; Kowalski, H.; Jackson, N.; Ye, C.; Martinez-Sobrido, L.; de la Torre, J. C.
10.1101/2024.08.01.606235 — microbiology — Posted on 2024-08-01
4783 Diet outperforms microbial transplant to drive microbiome recovery post-antibiotics
Kennedy, M. S.; Freiburger, A.; Cooper, M.; Beilsmith, K.; St. George, M. L.; Kalski, M.; Cham, C.; Guzzetta, A.; Ng, S. C.; Chan, F. K.; Rubin, D.; Henry, C. S.; Bergelson, J.; Chang, E. B.
10.1101/2024.08.01.606245 — microbiology — Posted on 2024-08-01
4785 Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity
Singh, S.; Gleason, C. E.; Fang, M.; Laimon, Y. N.; Khivansara, V.; Xie, S.; Durmaz, Y. T.; Sarkar, A.; Ngo, K.; Savla, V.; Li, Y.; Abu-Remaileh, M.; Li, X.; Tuladhar, B.; Odeh, R.; Hamkins-Indik, F.; He, D.; Membreno, M. W.; Nosrati, M.; Gushwa, N. N.; Leung, S. S. F.; Fraga-Walton, B.; Hernandez, L.; Baldomero, M. P.; Lent, B. M.; Spellmeyer, D.; Luna, J. F.; Hoang, D.; Gritsenko, Y.; Chand, M.; DeMart, M. K.; Metobo, S.; Bhatt, C.; Shapiro, J. A.; Yang, K.; Dupper, N. J.; Bockus, A. T.; Doench, J. G.; Aggen, J. B.; Liu, L.-F.; Levin, B.; Wang, E. W.; Vendrell, I.; Fischer, R.; Kessler, B. M
10.1101/2024.08.01.605889 — cancer biology — Posted on 2024-08-01
4787 Vanadium-dependent haloperoxidases from diverse microbes halogenate exogenous alkyl quinolone quorum sensing signals
Baumgartner, J. T.; McCaughey, C. S.; Fleming, H. S.; Lentz, A. R.; Sanchez, L. M.; McKinnie, S. M. K.
10.1101/2024.07.31.606109 — biochemistry — Posted on 2024-08-01
4788 SMURF1/2 are novel regulators of WNK1 stability
Jaykumar, A. B.; Plumber, S.; Binns, D.; Wichaidit, C.; Luby-Phelps, K.; Cobb, M. H.
10.1101/2024.07.31.606092 — biochemistry — Posted on 2024-08-01
4789 High-Efficiency Capture and Proteomic Analysis of Plasma-Derived Extracellular Vesicles through Affinity Purification
Zhang, G.-Y.; Ma, C.-x.; Ma, L.; Wei, D.; Wu, Y.-N.; Li, Y.; Xu, Z.-H.; Liu, Y.-F.; Cai, Y.-H.; Yu, E. Y.-W.; Zhu, Y.-F.; Zhang, H.
10.1101/2024.08.01.605729 — biochemistry — Posted on 2024-08-01
4793 Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females
Shain, A.; Savko, C.; Rokaw, S.; Jaafar, F.; Rieder, A.; Wright, M. K.; Phillips, J. A.; Konja, N.; Michael, S.; Mathews, H.; Jerjees, G.; Bailey, B.; Sussman, M.
10.1101/2024.08.01.606074 — molecular biology — Posted on 2024-08-01
4795 PDS5s control the Arabidopsis 3D genome by suppressing the formation of TAD-like domains
Goebel, A. M.; Zhou, S.; Wang, Z.; Tzourtzou, S.; Himmelbach, A.; Zheng, S.; Pradillo, M.; Liu, C.; JIANG, H.
10.1101/2024.07.31.606105 — molecular biology — Posted on 2024-08-01
4796 MinD2 modulates cell shape and motility in the archaeon Haloferax volcanii
Patro, M.; Sivabalasarma, S.; Gfrerer, S.; Rodriguez, M.; Nussbaum, P.; Ithurbide, S.; Albers, S.-V.
10.1101/2024.08.01.606218 — microbiology — Posted on 2024-08-01
4797 Plasmids encode and can mobilize onion pathogenicity in Pantoea agglomerans
Shin, G. Y.; Asselin, J. A.; Smith, A.; Aegerter, B.; Coutinho, T.; Zhao, M.; Dutta, B.; Mazzone, J.; Neupane, R.; Gugino, B.; Hoepting, C.; Khanal, M.; Malla, S.; Nischwitz, C.; Sidhu, J.; Burke, A. M.; Davey, J.; Uchanski, M.; Derie, M. L.; du Toit, L. J.; Stresow, S.; Bonasera, J. M.; Stodghill, P.; Kvitko, B. H.
10.1101/2024.08.01.606178 — microbiology — Posted on 2024-08-01
4799 Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides
Fu, Y.; Luo, X.-D.; Li, J.-Z.; Mo, Q.-Y.; Wang, X.; Zhao, Y.; Zhang, Y.-M.; Luo, H.-T.; Xia, D.-Y.; Ma, W.-Q.; Chen, J.-Y.; Wang, L.-H.; Deng, Q.-Y.; Ben, L.; Kashif Saleemi, M.; Jiang, X.-Z.; Chen, J.; Miao, K.; Lin, Z.-P.; Zhang, P.; Ye, H.; Cao, Q.-Y.; Zhu, Y.-W.; Yang, L.; Tu, Q.; Wang, W.
10.1101/2024.08.01.606206 — microbiology — Posted on 2024-08-01
4800 Visualizing Liquid Distribution Across Hyphal Networks with Cellular Resolution
Clark, A. J.; Masters-Clark, E.; Moratto, E.; Junier, P.; Stanley, C. E.
10.1101/2024.08.01.606151 — microbiology — Posted on 2024-08-01
4801 Valorisation of spent cultivated meat media for recombinant FGF2 production in GRAS Lactococcus lactis
Rizal, J.; Mainali, P.; Quek, J. P.; Tan, L. L.; Bi, J.; Chan, A. J.; Gaffoor, A. A.; Chew, L. J. M.; Sugii, S.; Ng, S. K.; Ow, D. S.-W.; Wong, F. T.
10.1101/2024.08.01.606190 — microbiology — Posted on 2024-08-01
4803 The RND efflux pump EefABC is highly conserved within lineages of E. coli commonly associated with infection.
Pugh, H.; Darby, E.; Burgess, L.; Colclough, A.; Meosa-John, A.-R.; Dunn, S.; Connor, C.; Perry, E.; McNally, A.; Bavro, V.; Blair, J. M. A.
10.1101/2024.08.01.606150 — microbiology — Posted on 2024-08-01
4806 IL-27 Stablizes Myc-Mediated Transcription In Memory-Fated, Vaccine-Elicited CD8+ T Cells
Kedl, R. M.; Thompson, S. B.; Harbell, M.; Manalastas, J.; Ivanova, D. L.; Riemondy, K. A.; Lasda, E.; Chen, V.; Hesselberth, J. R.; Phan, A. T. A.; Christian, D. A.; Hunter, C.; Brunetti, T.; Klarquist, J.; Gapin, L.
10.1101/2024.07.31.606026 — immunology — Posted on 2024-08-01
4807 Synergistic combination therapy with ONC201 or ONC206, Enzalutamide and Darolutamide in preclinical studies of castration-resistant prostate cancer
Wu, L. J.; Pinho-Schwermann, M.; Zhou, L.; Zhang, L.; Huntington, K. E.; Malpass, R.; Seyhan, A. A.; Carneiro, B. A.; El-Deiry, W. S.
10.1101/2024.07.31.606054 — cancer biology — Posted on 2024-08-01
4808 Contact-based thymidylate transfer promotes collective tumor growth
Siddiqui, M. A.; Roemer, A. M. A.; Pinna, L.; Ramesh, V.; Moeller, S. S.; Gollavilli, P. N.; Turtos, A. M.; Varghese, S.; Guldborg, L. B.; Palani, N. P.; Napoli, F.; Volante, M.; Swietach, P.; Ceppi, P.
10.1101/2024.07.31.606056 — cancer biology — Posted on 2024-08-01
4811 Neutralizing antibodies elicited in sequentially immunized macaques recognize V3 residues on altered conformations of HIV-1 Env trimer
DeLaitsch, A. T.; Keeffe, J. R.; Gristick, H. B.; Lee, J. A.; Ding, W.; Liu, W.; Skelly, A. N.; Shaw, G. M.; Hahn, B. H.; Bjorkman, P. J.
10.1101/2024.07.31.605918 — immunology — Posted on 2024-08-01
4818 Sustained Strain Applied at High Rates Drives Dynamic Tensioning in Epithelial Cells
Safa, B. T.; Rosenbohm, J.; Esfahani, A. M.; Minnick, G.; Moghaddam, A. O.; Lavrik, N. V.; Huang, C.; Charras, G.; Kabla, A.; Yang, R.
10.1101/2024.07.31.606021 — biophysics — Posted on 2024-08-01
4821 Interferon-induced activation state of circulating dendritic cells and monocytes triggered by yellow fever vaccination correlates with early protective antibody responses
Winheim, E.; Santos-Peral, A.; Ehm, T.; Rinke, L.; Riemer, S.; Zaucha, M.; Goresch, S.; Lehmann, L.; Eisenaecher, K.; Pritsch, M.; Spaeth, G. B.; Straub, T.; Rothenfusser, S.; Krug, A. B.
10.1101/2024.07.31.606034 — immunology — Posted on 2024-08-01
4822 Experience instructs the refinement of feature-selectivity in the mouse primary visual thalamus
Sonoda, T.; Stephany, C.-E.; Kelley, K.; Kang, D.; Wu, R.; Uzgare, M. R.; Fagiolini, M.; Greenberg, M. E.; Chen, C.
10.1101/2024.07.31.605460 — neuroscience — Posted on 2024-08-01
4825 Sphingosine-1-phosphate receptor 3 activation promotes sociability and regulates the expression of genes associated with anxiolytic-like behavior
Castro-Vildosola, J.; Bryan, C.-A.; Tajamal, N.; Jonnalagadda, S. A.; Kasturi, A.; Tilly, J.; Garcia, I.; Kumar, R.; Fried, N. T.; Hala, T.; Corbett, B. F.
10.1101/2024.07.31.606030 — neuroscience — Posted on 2024-08-01
4827 Comparative lifespan and healthspan of nonhuman primate species common to biomedical research
Huber, H. F.; Ainsworth, H. C.; Quillen, E. E.; Salmon, A.; Ross, C.; Azhar, A. D.; Bales, K.; Basso, M. A.; Coleman, K.; Colman, R.; Darusman, H. S.; Hopkins, B.; Hotchkiss, C. E.; Jorgensen, M. J.; Kavanagh, K.; Li, C.; Mattison, J. A.; Nathanielsz, P. W.; Saputro, S.; Scorpio, D. G.; Sosa, P.-M.; Vallender, E. J.; Wang, Y.; Zeiss, C. J.; Shively, C. A.; Cox, L. A.
10.1101/2024.07.31.606010 — physiology — Posted on 2024-08-01
4834 Infiltrating lipid-rich macrophage subpopulations identified as a regulator of increasing prostate size in human benign prostatic hyperplasia
Lanman, N. A.; Meco, E.; Fitchev, P.; Kolliegbo, A. K.; Broman, M. M.; Filipovich, Y.; Kothandaraman, H.; Cresswell, G. M.; Talaty, P.; Antoniak, M.; Brumer, S.; Glaser, A. P.; Higgins, A. M.; Helfand, B. T.; Franco, O. E.; Crawford, S. E.; Ratliff, T. L.; Hayward, S. W.; Vickman, R. E.
10.1101/2024.06.07.597992 — immunology — Posted on 2024-08-01
4838 Extensive mutual influences of SMC complexes shape 3D genome folding
Zhang, H.; Zhao, H.; Shu, L.; Liu, F.; Lin, E.; Xia, S.; Wang, B.; Wang, M.; Shan, F.; Lin, Y.; Zhang, L.; Gu, Y.; Blobel, G.
10.1101/2024.07.31.606012 — cell biology — Posted on 2024-08-01
4839 Bacteria face trade-offs in the decomposition of complex biopolymers
Guseva, K.; Mohrlok, M.; Alteio, L.; Schmidt, H.; Pollak, S.; Kaiser, C.
10.1101/2023.10.03.560709 — microbiology — Posted on 2024-08-01
4842 REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness
Mortazavi, N.; Talwar, P.; Koshmanova, E.; Sharifpour, R.; Beckers, E.; Berger, A.; Campbell, I.; Paparella, I.; Balda, F.; Dardour Hamzaoui, I.; Berthomier, C.; Bastin, C.; Phillips, C.; Maquet, P.; Collette, F.; Zubkov, M.; Lamalle, L.; Vandewalle, G.
10.1101/2024.07.12.603275 — neuroscience — Posted on 2024-08-01
4843 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.
10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-08-01
4844 Decoding in the fourth dimension: Classification of temporal patterns and their generalization across locations
Santos-Mayo, A.; Gilbert, F.; Ahumada, L.; Traiser, C.; Engle, H.; Panitz, C.; Ding, M.; Keil, A.
10.1101/2024.06.19.599699 — neuroscience — Posted on 2024-08-01
4845 Combining systems and synthetic biology for in vivo enzymology
Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.
10.1101/2024.02.02.578620 — systems biology — Posted on 2024-08-01
4848 Expanding the space of self-reproducing RNAs using probabilistic generative models
Lambert, C. N.; Opuu, V.; Calvanese, F.; Zamponi, F.; Hayden, E. J.; Weigt, M.; Smerlak, M.; Nghe, P.
10.1101/2024.07.31.605758 — biochemistry — Posted on 2024-08-01
4850 G-quadruplex formation in GCK and TM6SF2 are targets for differential DNA methylation in metabolic disease and hepatocellular carcinoma patients
Lahnsteiner, A.; Ellmer, V.; Oberlercher, A.; Liutkeviciute, Z.; Schoenauer, E.; Paulweber, B.; Aigner, E.; Risch, A.
10.1101/2024.03.21.585382 — genetics — Posted on 2024-08-01
4851 A genetic toolbox for the turquoise killifish identifies sporadic age-related cancer
Rozenberg, I.; Franek, R.; Moses, E.; Atlan, T.; Diehl, M.; Oron-Gottesman, A.; Bergman, M.; Astre, G.; Rosental, B.; Chrzanowski, H.; Harel, I.
10.1101/2023.05.01.538839 — genetics — Posted on 2024-08-01
4853 Single-molecule tracking reveals the dynamics of Ipl1 recruitment to the kinetochores and spindles in S. cerevisiae
Podh, N. K.; Das, A.; Kumari, A.; Garg, K.; Yadav, R.; Kashyap, K.; Islam, S.; Gupta, A.; Mehta, G.
10.1101/2024.08.01.606162 — cell biology — Posted on 2024-08-01
4854 Src promotes tumor cell invasion by hijacking the translation machinery
BONNARD, B.; Chatefau, A.; Dourthe, C.; Di Tommaso, S.; Dupuy, J.-W.; Mahouche, I.; Solorzano, J.; Le Bras, M.; Raymond, A.-A.; Moreau, V.; Jabouille, A.; Blangy, A.; Saltel, F.
10.1101/2024.08.01.606119 — cell biology — Posted on 2024-08-01
4855 Silk-Ovarioids: Establishment and characterization of human ovarian primary cells 3D-model system
Di Nisio, V.; Li, T.; Xiao, Z.; Papaikonomou, K.; Damdimopoulos, A.; Vegvari, A.; Lebre, F.; Alfaro-Moreno, E.; Pedersen, M.; Svingen, T.; Zubarev, R.; Acharya, G.; Damdimopoulou, P.; Salumets, A.
10.1101/2024.07.31.606024 — cell biology — Posted on 2024-08-01
4856 The impact of physical activity on physical performance, mitochondrial bioenergetics, ROS production and calcium handling across the human adult lifespan
Cefis, M.; Marcangeli, V.; Hammad, R.; Granet, J.; Leduc-Gaudet, J.-P.; Gaudreau, P.; Trumpff, C.; Huang, Q.; Picard, M.; Aubertin-Leheudre, M.; Belanger, M.; Morais, J. A.; Gouspillou, G.
10.1101/2024.07.09.602758 — cell biology — Posted on 2024-08-01
4858 DeepOrientation: Deep Orientation Estimation of Macromolecules in Cryo-electron tomography
Hajarolasvadi, N.; Phelippeau, H.; Martinez-Sanchez, A.; Brandt, R.; Suau, P.-N.; Baum, D.
10.1101/2024.07.12.603241 — molecular biology — Posted on 2024-08-01
4859 MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
Graca, A. P.; Nikitushkin, V.; Ellerhorst, M.; Vilhena, C.; Klassert, T.; Starick, A.; Siemers, M.; Al-Jammal, W. K.; Vilotijevic, I.; Slevogt, H.; Papenfort, K.; Lackner, G.
10.1101/2024.03.26.586840 — microbiology — Posted on 2024-08-01
4860 Impact of aging on the GABAB receptor-mediated connectome
Vasquez, E.; Oresti, G. M.; Paez, M. D.; Callegari, E. A.; Masone, D. F.; Munoz, E. M.
10.1101/2024.07.31.606013 — neuroscience — Posted on 2024-08-01
4862 Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification
Wala, J.; Dalin, S.; Webster, S.; Shapira, O.; Busanovich, J.; Beroukhim, R.; Bandopadhayay, P.; Rendo, V.
10.1101/2024.07.31.606009 — cancer biology — Posted on 2024-08-01
4865 Laminin 111 triggers cell quiescence and long-term survival by inducing IQGAP1-mediated cytosolic scaffolding of ERK and BAD inactivation
Yu, C.; Malijauskaite, S.; Hinze, C.; Franzoni, M.; Hickey, S.; Marcar, L.; Peak-Chew, S. Y.; Cryar, A.; Bain, C.; Marsden, J.; Allardyce, J. M.; Mendes-Pereira, A. M.; McMahon, H. T.; Thalassinos, K.; McGourty, K.; Boucrot, E.
10.1101/2024.08.01.606017 — cell biology — Posted on 2024-08-01
4868 Human-like APOBEC3 gene expression and anti-viral responses following replacement of mouse Apobec3 with the 7-gene human APOBEC3 locus
Kirkwood, N. K.; Prosser, H.; Yap, M. W.; Gibson, J.; Cook, R.; Reddin, I.; Stranger, A.; Howes, E.; Zainal, N.; Periyasamy, M.; Conticello, S. G.; Thomas, G. J.; Scott, J.; Bishop, K. N.; Ali, S.; Bradley, A.; Fenton, T. R.
10.1101/2024.07.30.605801 — cancer biology — Posted on 2024-08-01
4869 Metabolic modelling reveals increased autonomy and antagonism in type 2 diabetic gut microbiota
Kadibalban, A. S.; Kunstner, A.; Schroder, T.; Kaleta, C.; Zauleck, J.; Witt, O.; Marinos, G.
10.1101/2024.07.31.605966 — systems biology — Posted on 2024-08-01
4870 JM-20 administration to animals with lesion of the nigrostriatal dopamine pathway induced by 6-hydroxydopamine, partially reverses motor damage and oxidative stress
Fonseca Fonseca, L. A.; Tano Portuondo, L. R.; Ramirez-Sanchez, J.; Pavon Fuentes, N.; Mondelo Rodriguez, A.; Amaral da Silva, V. D.; Lima Costa, S.; Nunez-Figueredo, Y.
10.1101/2024.07.30.605870 — neuroscience — Posted on 2024-08-01
4872 Histone H3 E50K mutation confers oncogenic activity and supports an EMT phenotype
Sad, K.; Jones, C. Y.; Fawwal, D. V.; Hill, E. J.; Skinner, K.; Lustenberger, S.; Lee, R. S.; Elayavalli, S. R.; Farhi, J.; Lemon, L. D.; Fasken, M. B.; Hong, A. L.; Sloan, S. A.; Corbett, A. H.; Spangle, J. M.
10.1101/2023.10.11.561775 — cancer biology — Posted on 2024-08-01
4880 Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus
Otsubo, K.; Sakashita, N.; Nishimoto, Y.; Sato, Y.; Tsutsui, T.; Kobayashi, K.; Suzuki, K.; Segi-Nishida, E.
10.1101/2023.11.17.567646 — neuroscience — Posted on 2024-08-01
4881 Reward history cues focal attention in whisker somatosensory cortex
Ramamurthy, D. L.; Rodriguez, L.; Cen, C.; Li, S.; Chen, A.; Feldman, D. E.
10.1101/2024.07.17.603927 — neuroscience — Posted on 2024-08-01