bioRxiv directory

1 Notch1 regulates breast cancer stem cell function via a non-canonical cleavage-independent pathway

Sui, L.; Wang, S.; Rodriguez, R. K.; Sim, D.; Bhattacharya, N.; Blois, A. L.; Schlaeger, T.; Chen, S.; Aziz, S.; Rogers, M. S.; Bielenberg, D. R.; Akslen, L. A.; Watnick, R. S.

10.1101/2020.02.28.970764 — cancer biology — Posted on 2020-02-29

2 Ruler elements in chromatin remodelers set nucleosome array spacing and phasing

Oberbeckmann, E.; Niebauer, V.; Watanabe, S.; Farnung, L.; Moldt, M.; Schmid, A.; Cramer, P.; Peterson, C. L.; Eustermann, S.; Hopfner, K.-P.; Korber, P.

10.1101/2020.02.28.969618 — biochemistry — Posted on 2020-02-29

3 Downregulation of the essential Rrp44 ribonuclease causes extensive ultra-structure cell modifications in Trypanosoma brucei

Cesaro, G.; Hiraiwa, P. M.; Carneiro, F. R. G.; Rouam, V.; Legrand, P.; Conesa, J. J.; Soares, M. J.; Refregiers, M.; Pereiro, E.; Guimaraes, B. G.; Jamme, F.; Zanchin, N. I. T.

10.1101/2020.02.29.971424 — cell biology — Posted on 2020-02-29

4 Large-Scale Analysis of Cell Death Phenotypic Heterogeneity

Inde, Z.; Forcina, G. C.; Denton, K.; Dixon, S. J.

10.1101/2020.02.28.970079 — cancer biology — Posted on 2020-02-29

5 GOT1 Inhibition Primes Pancreatic Cancer for Ferroptosis through the Autophagic Release of Labile Iron

Kremer, D. M.; Nelson, B. S.; Lin, L.; Yarosz, E.; Halbrook, C. J.; Kerk, S. A.; Sajjakulnukit, P.; Myers, A.; Thurston, G.; Hou, S.; Carpenter, E. S.; Andren, A.; Nwosu, Z.; Cusmano, N.; Wisner, S.; Ramos, J.; Gao, T.; Sastra, S. A.; Palermo, C. F.; Badgley, M. A.; Zhang, L.; Asara, J. M.; Pasca di Magliano, M.; Shah, Y. M.; Crawford, H. C.; Olive, K. P.; Lyssiotis, C. A.

10.1101/2020.02.28.970228 — cancer biology — Posted on 2020-02-29

6 An Improved 4'-Aminomethyltroxsalen-Based DNA Crosslinker for Biotinylation of DNA

Wielenberg, K.; Wang, M.; Yang, M.; Ozer, A.; Lis, J.; Lin, H.

10.1101/2020.02.29.971317 — biochemistry — Posted on 2020-02-29

7 Transient opening of tricellular vertices controls paracellular transport through the follicle epithelium during Drosophila oogenesis

Isasti-Sanchez, J.; Munz-Zeise, F.; Luschnig, S.

10.1101/2020.02.29.971168 — developmental biology — Posted on 2020-02-29

8 Identifying spawning activity in aquatic species based on environmental DNA spikes

Tsuji, S.; Shibata, N.

10.1101/2020.01.28.924167 — molecular biology — Posted on 2020-02-29

9 Learning not to remember: How predicting the future impairs encoding of the present

Sherman, B. E.; Turk-Browne, N. B.

10.1101/851147 — neuroscience — Posted on 2020-02-29

10 The PD-L1/PD-1 Axis Blocks Neutrophil Cytotoxicity In Cancer

Gershkovitz, M.; Yajuk, O.; Fainsod-Levi, T.; Granot, Z.

10.1101/2020.02.28.969410 — immunology — Posted on 2020-02-29

11 Birth weight predicts psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

Madden, R. A.; McCartney, D. L.; Walker, R. M.; Hillary, R. F.; Bermingham, M. L.; Rawlik, K.; Morris, S. W.; Campbell, A.; Porteous, D. J.; Deary, I. J.; Evans, K. L.; Hafferty, J.; McIntosh, A. M.; Marioni, R. E.

10.1101/664045 — genomics — Posted on 2020-02-29

12 Correlating predicted epigenetic marks with expression data to find interactions between SNPs and genes

Despinasse, A.; Park, Y.; Lapi, M.; Kellis, M.

10.1101/2020.02.29.970962 — bioinformatics — Posted on 2020-02-29

13 In vitro pancreatic islet cluster expansion facilitated by hormones and chemicals

Lin, J.-Y.; Cheng, J.; Du, Y.-Q.; Pan, W.; Zhang, Z.; Wang, J.; Yang, Z.; Yang, F.; Xu, Y.-F.; Lin, H.; An, W.-T.; Wang, J.; An, J.; Chai, R.-J.; Sha, X.; Hu, H.-L.; Sun, J.; Yu, X.

10.1101/2019.12.16.873596 — cell biology — Posted on 2020-02-29

14 Spatially-Resolved Live Cell Tagging and Isolation Using Protected Photoactivatable Cell Dyes

Genshaft, A. S.; Ziegler, C. G. K.; Tzouanas, C. N.; Mead, B. E.; Jaeger, A. M.; Navia, A. W.; King, R. P.; Jacks, T.; Van Humbeck, J. F.; Shalek, A. K.

10.1101/2020.02.28.966598 — systems biology — Posted on 2020-02-29

15 In search of the RNA world on Mars

Mojarro, A.; Jin, L.; Szostak, J. W.; Head, J. W.; Zuber, M. T.

10.1101/2020.02.28.964486 — molecular biology — Posted on 2020-02-29

16 Dense cellular segmentation using 2D-3D neural network ensembles for electron microscopy

Guay, M.; Emam, Z.; Anderson, A.; Aronova, M.; Leapman, R. D.

10.1101/2020.01.05.895003 — microbiology — Posted on 2020-02-29

17 Genome-wide Identification and Analysis of Enhancer Regulated microRNAs Across 31 Human Cancers

Tang, F.; Lang, M.; Wang, W.; Li, C.; Tan, Z. t.; Yue, J.; Guo, Z.

10.1101/2020.02.21.960351 — bioinformatics — Posted on 2020-02-29

18 Adding carbon fiber to shoe soles does not improve running economy: a muscle-level explanation

Beck, O. N.; Golyski, P. R.; Sawicki, G. S.

10.1101/2020.02.28.969584 — bioengineering — Posted on 2020-02-29

19 Kinematic signatures of learning that emerge in a real-world motor skill task

Haar, S.; van Assel, C. M.; Faisal, A. A.

10.1101/612218 — neuroscience — Posted on 2020-02-29

20 Visual search mimics configural processing in associative learning

Perez, O. D.; Narasiwodeyar, S.; Soto, F. A.

10.1101/713420 — animal behavior and cognition — Posted on 2020-02-29

21 The cis-regulatory codes of response to combined heat and drought stress in Arabidopsis thaliana

Azodi, C. B.; Lloyd, J. P.; Shiu, S.-H.

10.1101/2020.02.28.969261 — genomics — Posted on 2020-02-29

22 Morphogenesis is transcriptionally coupled to neurogenesis during peripheral olfactory organ development

Aguillon, R.; Madelaine, R.; Guturu, H.; Link, S.; Dufourcq, P.; Lecaudey, V.; Bejerano, G.; Blader, P.; Batut, J.

10.1101/725705 — developmental biology — Posted on 2020-02-29

23 Understanding biochemical design principles with ensembles of canonical non-linear models

Bromig, L.; Kremling, A.; Marin-Sanguino, A.

10.1101/2020.02.28.969170 — systems biology — Posted on 2020-02-29

24 Microeconomics of metabolism: Overflow metabolism as Giffen behaviour

Yamagishi, J. F.; Hatakeyama, T. S.

10.1101/613166 — systems biology — Posted on 2020-02-29

25 Nested oscillations and brain connectivity during sequential stages of feature-based attention

Pagnotta, M. F.; Pascucci, D.; Plomp, G.

10.1101/2020.02.28.969253 — neuroscience — Posted on 2020-02-29

26 Curvature domains in V4 of Macaque Monkey

Hu, J.; Song, X. M.; Wang, Q.; Roe, A. W.

10.1101/2020.02.28.969329 — neuroscience — Posted on 2020-02-29

27 Polygenic architecture of human neuroanatomical diversity

Biton, A.; Traut, N.; Poline, J.-B.; Aribisala, B. S.; Bastin, M. E.; Bülow, R.; Cox, S. R.; Deary, I. J.; Grabe, H. J.; Hagenaars, S.; Hashimoto, R.; Munoz Maniega, S.; Nauck, M.; Royle, N. A.; Teumer, A.; Valdes Hernandez, M.; Völker, U.; Wardlaw, J. M.; Wittfeld, K.; Alzheimer's Disease Neuroimaging Initiative, ; Bourgeron, T.; Toro, R.

10.1101/592337 — neuroscience — Posted on 2020-02-29

28 Emergence of optrA-mediated linezolid resistance in multiple lineages and plasmids of Enterococcus faecalis revealed by long read sequencing

McHugh, M. P.; Parcell, B. J.; Pettigrew, K. A.; Toner, G.; Khatamzas, E.; Karcher, A. M.; Walker, J.; Weir, R.; Meunier, D.; Hopkins, K. L.; Woodford, N.; Templeton, K. E.; Gillespie, S. H.; Holden, M. T.

10.1101/2020.02.28.969568 — microbiology — Posted on 2020-02-29

29 Host-microbiome protein-protein interactions capture mechanisms in human disease

Beltran, J. F.; Brito, I.

10.1101/821926 — microbiology — Posted on 2020-02-29

30 Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations

Grujic, O.; Phung, T. N.; Kwon, S. B.; Arneson, A.; Lee, Y.; Lohmueller, K. E.; Ernst, J.

10.1101/722876 — genomics — Posted on 2020-02-29

31 Models for Eco-evolutionary Extinction Vortices and their Detection

Nabutanyi, P.; Wittmann, M. J.

10.1101/2020.02.28.969402 — evolutionary biology — Posted on 2020-02-29

32 Host "cleansing zone" at secondary contact: a new pattern in host-parasite population genetics.

Martinu, J.; Poosakkannu, A.; Stefka, J.; Hypsa, V.

10.1101/2020.02.28.969279 — evolutionary biology — Posted on 2020-02-29

33 Mitochondrial DNA Sequence Diversity in Mammals: a Correlation Between the Effective and Census Population Sizes

James, J.; Eyre-Walker, A.

10.1101/2020.02.28.969592 — evolutionary biology — Posted on 2020-02-29

34 Rapid, precise, and reliable phenotyping of delay discounting using a Bayesian learning algorithm

Ahn, W.-Y.; Gu, H.; Shen, Y.; Haines, N.; Hahn, H.; Teater, J. E.; Myung, J. I.; Pitt, M. A.

10.1101/567412 — neuroscience — Posted on 2020-02-29

35 Perceptual decisions about object shape bias visuomotor coordination during rapid interception

Barany, D. A.; Granados, A. G.; Schrayer, M.; Cutts, S. A.; Singh, T.

10.1101/821074 — neuroscience — Posted on 2020-02-29

36 Role of post-trial visual feedback on unintentional force drift during isometric finger force production tasks

S, B.; Rachaveti, D.; SKM, V.

10.1101/864413 — neuroscience — Posted on 2020-02-29

37 Light environment drives evolution of color vision genes in butterflies and moths.

Sondhi, Y.; Ellis, E. A.; Theobald, J. C.; Kawahara, A. Y.

10.1101/2020.02.29.965335 — evolutionary biology — Posted on 2020-02-29

38 Population Specific Adaptations in Venom Production to Abiotic Stressors in a Widely Distributed Cnidarian

Sachkova, M. Y.; Macrander, J.; Surm, J. M.; Aharoni, R.; Menard-Harvey, S. S.; Klock, A.; Leach, W. B.; Reitzel, A. M.; Moran, Y.

10.1101/2020.02.28.969204 — evolutionary biology — Posted on 2020-02-29

39 Systematic tools for reprogramming plant gene expression in a simple model, Marchantia polymorpha.

Sauret-Gueto, S.; Frangedakis, E.; Silvestri, L.; Rebmann, M.; Tomaselli, M.; Markel, K.; Delmans, M.; West, A.; Patron, N. J.; Haseloff, J.

10.1101/2020.02.29.971002 — synthetic biology — Posted on 2020-02-29

40 Nucleosome-constrained loop extrusion model for the origin of topologically associating domains

Bailey, M. L. P.; Surovtsev, I. V.; Yan, H.; Williams, J. F.; Mochrie, S.; King, M. C.

10.1101/2020.02.29.969683 — cell biology — Posted on 2020-02-29

41 Subtype-specific epigenomic landscape and 3D genome structure in bladder cancer

Iyyanki, T. S.; Zhang, B.; Jin, Q.; Yang, H.; Liu, T.; Wang, X.; Song, F.; Luan, Y.; Yamashita, H.; Wang, L.; Warrick, J.; Raman, J.; Meeks, J.; DeGraff, D. J.; Yue, F.

10.1101/2020.02.26.966697 — genomics — Posted on 2020-02-29

42 ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy

You, J.-S.; Singh, N.; Reyes-Ordonez, A.; Khanna, N.; Bao, Z.; Zhao, H.; Chen, J.

10.1101/2020.02.28.970756 — cell biology — Posted on 2020-02-29

43 ACCLIMATION OF PHOTOSYNTHESIS TO THE ENVIRONMENT 1 regulates Photosystem II Supercomplex dynamics in response to light in Chlamydomonas reinhardtii

Johnson, X.; Caffarri, S.; Chazaux, M.; Da Graca, J.; Cuine, S.; Floriani, M.; Brzezowski, P.; Peltier, G.; Genty, B.; Alric, J.

10.1101/2020.02.26.966580 — plant biology — Posted on 2020-02-29

44 Non-Langmuir kinetics of DNA surface hybridization

Vanjur, L.; Carzaniga, T.; Casiraghi, L.; Chiari, M.; Zanchetta, G.; Buscaglia, M.

10.1101/2020.02.27.968081 — biophysics — Posted on 2020-02-29

45 Genes and Pathways for Plasma Lipid Traits via Multi-tissue Multi-omics Systems Analysis

Zhao, Y.; Blencowe, M.; Saleem, Z.; Ahn, I. S.; Mäkinen, V.-P.; Luk, H.; Yang, X.

10.1101/2020.02.28.970368 — systems biology — Posted on 2020-02-29

46 Metabolic multi-stability and hysteresis in a model aerobe-anaerobe microbiome community

Khazaei, T.; Williams, R. L.; Bogatyrev, S. R.; Doyle, J. C.; Henry, C. S.; Ismagilov, R. F.

10.1101/2020.02.28.968941 — ecology — Posted on 2020-02-29

47 The Effect of a Virtual No-Step Zone on Balance Control in Walking

Fettrow, T.; DiBianca, S.; Dos Santos, F.; Reimann, H.; Jeka, J.

10.1101/2020.02.28.970152 — neuroscience — Posted on 2020-02-29

48 Cellular and structural basis of synthesis of the unique intermediate dehydro-F420-0 in mycobacteria

Grinter, R.; Ney, B.; Brammananth, R.; Barlow, C. K.; Cordero, P. R. F.; Gillett, D. L.; Izore, T.; Cryle, M.; Harold, L.; Cook, G. M.; Taiaroa, G.; Williamson, D. A.; Warden, A. C.; Oakeshott, J. G.; Taylor, M. C.; Crellin, P. K.; Jackson, C. J.; Schittenhelm, R. B.; Coppel, R. L.; Greening, C.

10.1101/2020.02.27.968891 — biochemistry — Posted on 2020-02-29

49 A Cretaceous bug indicates that exaggerated antennae may be a double-edged sword in evolution

Du, B.-J.; Chen, R.; Tao, W.-T.; Shi, H.-L.; Bu, W.-J.; Liu, Y.; Ma, S.; Ni, M.-Y.; Kong, F.-L.; Xiao, J.-H.; Huang, D.-W.

10.1101/2020.02.11.942920 — paleontology — Posted on 2020-02-29

50 Individual behavioral type captured by a Bayesian model comparison of cap making by sponge crabs

Harada, K.; Hayashi, N.; Kagaya, K.

10.1101/330787 — animal behavior and cognition — Posted on 2020-02-29

51 Crystallography of lamin A facilitated by chimeric fusions

Stalmans, G.; Lilina, A. V.; Strelkov, S. V.

10.1101/2020.02.28.969220 — molecular biology — Posted on 2020-02-28

52 Parkin coordinates mitochondrial lipid remodeling to execute mitophagy

Lin, C.-C.; Yan, J.; Kapur, M. D.; Norris, K. L.; Hsieh, C.-W.; Lai, C.-H.; Vitale, N.; Lim, K.-L.; Guan, Z.; Chi, J.-T.; Yang, W.-Y.; Yao, T.-P.

10.1101/2020.02.28.970210 — cell biology — Posted on 2020-02-28

53 Unique structural features of mammalian NEIL2 DNA glycosylase prime its activity for diverse DNA substrates and environments

Eckenroth, B. E.; Cao, V.; Averill, A. M.; Dragon, J. A.; Doublie, S.

10.1101/2020.02.28.970129 — biochemistry — Posted on 2020-02-28

54 Manipulation of a cation-{Pi} sandwich expands knowledge of the conformational flexibility of mammalian phenylalanine hydroxylase

Arturo, E. C.; Merkel, G.; Hansen, M. R.; Lisowski, S.; Almeida, D.; Gupta, K.; Jaffe, E. K.

10.1101/2020.02.28.969873 — biochemistry — Posted on 2020-02-28

55 In-cell architecture of an actively transcribing-translating expressome

O'Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Bloetz, C.; Hagen, W. J. H.; Cramer, P.; Stuelke, J.; Mahamid, J.; Rappsilber, J.

10.1101/2020.02.28.970111 — molecular biology — Posted on 2020-02-28

56 Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion

Morrison, J. A.; McLennan, R.; Teddy, J. M.; Scott, A. R.; Kasemeier-Kulesa, J. C.; Gogol, M. M.; Kulesa, P. M.

10.1101/2020.02.28.969915 — developmental biology — Posted on 2020-02-28

57 The low complexity regions in the C-terminus are essential for the subcellular localisation of Leishmania casein kinase 1 but not for its activity

Martel, D.; Pine, S.; Bartsch, K.; Clos, J.; Spaeth, G. F.; RACHIDI, N.

10.1101/2020.02.28.969741 — cell biology — Posted on 2020-02-28

58 Exploring the Pharmacological Mechanism of Bezoar on Cerebral Ischemic Stroke using a Network Pharmacology Approach

Wang, Q.; Du, X.; Li, C.; Ren, B.; Deng, N.; Chen, C.; Wang, X.; Cheng, F.; Liu, M.

10.1101/2020.02.28.969436 — neuroscience — Posted on 2020-02-28

59 SNCAE46K transgenic Drosophila Model of Parkinsons Disease Confirmed the Causative Role of Oxidative Stress

Jahromi, S. R.; Saraf, R. R.; Finkelstein, D. I.; Haddadi, M.

10.1101/2020.02.28.969501 — neuroscience — Posted on 2020-02-28

60 Altered B cells homeostasis in child-onset immunoglobulin A vasculitis

Yang, S.; Liu, D.; Jiang, Y.; Wang, J.; Liu, J.; Xu, M.; Liu, C.

10.1101/2020.02.28.969444 — immunology — Posted on 2020-02-28

61 Controlling for Human Population Stratification in Rare Variant Association Studies

Bouaziz, M.; Mullaert, J.; Bigio, B.; Seeleuthner, Y.; Casanova, J.-L.; Alcais, A.; Abel, L.; Cobat, A.

10.1101/2020.02.28.969477 — genetics — Posted on 2020-02-28

62 Path sampling simulations reveal how the Q61L mutation restricts the dynamics of KRas

Roet, S.; Hooft, F.; Bolhuis, P. G.; Swenson, D. W. H.; Vreede, J.

10.1101/2020.02.28.969451 — cancer biology — Posted on 2020-02-28

63 New Radiological Classification of Glioma and validation with the survival analysis

Kamble, A. N.; Agrawal, N. K.; Koundal, S.; Bhargava, S.; Kamble, A. N.

10.1101/2020.02.28.969493 — cancer biology — Posted on 2020-02-28

64 SULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models

Brasil da Costa, F. H.; Lewis, M.; Truong, A.; Carson, D.; Farach-Carson, M. C.

10.1101/2020.02.28.969485 — cancer biology — Posted on 2020-02-28

65 STIG: Generation and simulated sequencing of synthetic T cell receptor repertoires

Woodcock, M.; Bortone, D.; Vincent, B.

10.1101/2020.02.28.969469 — genomics — Posted on 2020-02-28

66 Picomolar affinity antagonist and sustained signaling agonist peptide ligands for the adrenomedullin and calcitonin gene-related peptide receptors

Booe, J. M.; Warner, M. L.; Pioszak, A. A.

10.1101/2020.02.28.970301 — pharmacology and toxicology — Posted on 2020-02-28

67 Video Recording Can Conveniently Assay Mosquito Locomotor Activity

Araujo, M. d. S.; Guo, F.; Rosbash, M.

10.1101/2020.02.28.970566 — neuroscience — Posted on 2020-02-28

68 Tissue-resident CD4+ T helper cells assist protective respiratory mucosal B and CD8+ T cell memory responses

Son, Y. M.; Cheon, I. S.; Wu, Y.; Li, C.; Wang, Z.; Chen, Y.; Takahashi, Y.; Dent, A.; Kaplan, M.; Fu, Y.-X.; Taylor, J.; Cui, W.; Sun, J.

10.1101/2020.02.28.970400 — immunology — Posted on 2020-02-28

69 Spo0A suppresses sin locus expression in Clostridioides difficile

Govind, R.; Adhikari Dhungel, B.

10.1101/2020.02.28.968834 — genetics — Posted on 2020-02-28

70 Neglected Quaternary legacy of biodiversity for the Mountains of Southwest China

Wan, T.; Huang, H.; Oaks, J. R.; Jiang, X.; Knowles, L. L.

10.1101/2020.02.28.969089 — evolutionary biology — Posted on 2020-02-28

71 Controlled neighbor exchanges drive glassy behavior, intermittency and cell streaming in epithelial tissues

Das, A.; Sastry, S.; Bi, D.

10.1101/2020.02.28.970541 — biophysics — Posted on 2020-02-28

72 Massive windborne migration of Sahelian insects: Diversity, seasonality, altitude, and direction

Florio, J.; Veru, L.; Dao, A.; Yaro, A. S.; Diallo, M.; Sanogo, Z. L.; Samake, D.; Huestis, D. L.; Yossi, O.; Talamas, E.; Chomorro, L.; Frank, H. J.; Biondi, M.; Morkel, C.; Bartlett, C.; Linton, Y. M.; Strobach, E.; Chapman, J. W.; Reynolds, D. R.; Faiman, R.; Krajacich, B. J.; Smith, C. S.; Lehmann, T.

10.1101/2020.02.28.960195 — ecology — Posted on 2020-02-28

73 Three-dimensional reconstruction of individual helical nano-filament structures from atomic force microscopy topographs

Lutter, L.; Serpell, C.; Tuite, M.; Serpell, L.; Xue, W.-F.

10.1101/2020.02.28.970426 — biophysics — Posted on 2020-02-28

74 Super-resolved spatial transcriptomics by deep data fusion

Bergenstrahle, L.; He, B.; Bergenstrahle, J.; Andersson, A.; Lundeberg, J.; Zou, J.; Maaskola, J.

10.1101/2020.02.28.963413 — bioinformatics — Posted on 2020-02-28

75 MiR-101a loaded Extracellular Nanovesicles as Bioactive Carriers for Cardiac Repair

Wang, J.; Lee, C.; Deci, M. B.; Jasiewicz, N.; Canty, J.; Nguyen, J.

10.1101/2020.02.28.970269 — bioengineering — Posted on 2020-02-28

76 Cumulus cell acetyl-CoA metabolism from acetate is associated with maternal age but only partially with oocyte maturity

Anderson, S.; Xu, P.; Frey, A. J.; Goodspeed, J. R.; Doan, M. T.; Orris, J. J.; Clements, N.; Glassner, M. J.; Snyder, N. W.

10.1101/2020.02.28.970327 — biochemistry — Posted on 2020-02-28

77 Integrated Plasma and Tissue Proteomics Reveals Attractin Release by Intraluminal Thrombus of Abdominal Aortic Aneurysms and Improves Aneurysm Growth Prediction in Humans

Lee, R.; Cassimjee, I.; Huang, H.; Lapolla, P.; Chandrashekar, A.; Charles, P.; Kessler, B.; Fischer, R.; Handa, A.

10.1101/2020.02.28.970483 — systems biology — Posted on 2020-02-28

78 Modeling cannabinoids from a large-scale sample of Cannabis sativa chemotypes

Vergara, D.; Gaudino, R.; Blank, T.; Keegan, B.

10.1101/2020.02.28.970434 — plant biology — Posted on 2020-02-28

79 Chronic administration of a positive allosteric modulator at the alpha5-GABAA receptor reverses age-related dendritic shrinkage

Prevot, T. D.; Sumitomo, A.; Tomoda, T.; Knutson, D. E.; Li, G.; Cook, J. M.; Sibille, E.

10.1101/2020.02.28.964742 — neuroscience — Posted on 2020-02-28

80 Core and Matrix Thalamic Sub-Populations Relate to Spatio-Temporal Cortical Connectivity Gradients

Muller, E. J.; Munn, B.; Hearne, L. J.; Smith, J. B.; Fulcher, B.; Cocchi, L.; Shine, J.

10.1101/2020.02.28.970350 — neuroscience — Posted on 2020-02-28

81 Changes in perilesional V1 underlie training-induced recovery in cortically-blind patients

Barbot, A.; Das, A.; Melnick, M. D.; Cavanaugh, M. R.; Merriam, E. P.; Heeger, D. J.; Huxlin, K. R.

10.1101/2020.02.28.970285 — neuroscience — Posted on 2020-02-28

82 In Vivo Analysis of RNA Proximity Proteomes Using RiboPro

Lin, X.; Lawrenson, K.

10.1101/2020.02.28.970442 — molecular biology — Posted on 2020-02-28

83 Conserved regulation of omptin proteases by the PhoPQ two-component regulatory system in Enterobacteriaceae.

Cho, Y. H.; Fadle Aziz, M. R.; Sutradhar, T.; Bashal, J.; Cojocari, V.; McPhee, J. B.

10.1101/2020.02.28.965145 — microbiology — Posted on 2020-02-28

84 Genomic and phenotypic heterogeneity of clinical isolates of the human pathogens Aspergillus fumigatus, Aspergillus lentulus and Aspergillus fumigatiaffinis

Santos, R. A. C.; Steenwyk, J. L.; Rivero-Menendez, O.; Mead, M. E.; Silva, L. P.; Bastos, R. W.; Alastruey-Izquierdo, A.; Goldman, G. H.; Rokas, A.

10.1101/2020.02.28.970384 — microbiology — Posted on 2020-02-28

85 An original model of brain infection identifies B Streptococcus lipoprotein Blr as a ligand exploiting host endocytosis for blood-brain barrier crossing.

Benmimoun, B.; Papastefanaki, F.; Perichon, B.; Segklia, K.; Roby, N.; Miriagou, V.; Matsas, R.; Dramsi, S.; Speder, P.

10.1101/2020.02.28.970376 — microbiology — Posted on 2020-02-28

86 Redefining CD4 T cell residency: Helper T cells orchestrate protective humoral immunity in the lung

Swarnalekha, N.; Schreiner, D.; Litzler, L. C.; Iftikhar, S.; Kirchmeier, D.; Kuenzli, M.; King, C. G.

10.1101/2020.02.28.963280 — immunology — Posted on 2020-02-28

87 TP53 abnormalities correlate with immune infiltration and are associated with response to flotetuzumab, an investigational immunotherapy, in acute myeloid leukemia

Lai, C.; Vadakekolathu, J.; Reeder, S.; Church, S. E.; Hood, T.; Aldoss, I.; Godwin, J.; Wieduwilt, M. J.; Arellano, M.; Muth, J.; Ravandi, F.; Sweet, K.; Altmann, H.; Foulds, G. A.; Stolzel, F.; Middeke, J. M.; Ciciarello, M.; Curti, A.; Valk, P. J. M.; Lowenberg, B.; Bornhauser, M.; DiPersio, J. F.; Davidson-Moncada, J. K.; Rutella, S.

10.1101/2020.02.28.961391 — immunology — Posted on 2020-02-28

88 Improved reference genome of the arboviral vector Aedes albopictus

Palatini, U.; Masri, R.; Cosme, L. V.; Koren, S.; Thibaud-Nissen, F.; Biedler, J. K.; Krsticevic, F.; Johnston, S.; Halbach, R.; Crawford, J. E.; Antoshechkin, I.; Failloux, A.-B.; Pischedda, E.; Marconcini, M.; Ghurye, J.; Rhie, A.; Sharma, A.; Karagodin, D. A.; Jentette, J.; Gamez, S.; Miesen, P.; Caccone, A.; Sharakhova, M. V.; Tu, Z.; Papathanos, P. A.; van Rij, R. P.; Akbari, O. S.; Powell, J.; Phillippy, A. M.; Bonizzoni, M.

10.1101/2020.02.28.969527 — genomics — Posted on 2020-02-28

89 Meta-analysis of epigenome-wide association studies in Alzheime's disease highlights 220 differentially methylated loci across cortex

Smith, R.; Pishva, E.; Shireby, G.; Smith, A. R.; Roubroeks, J. A. Y.; Hannon, E.; Wheildon, G.; Mastroeni, D.; Gasparoni, G.; Riemenschneider, M.; Giese, A.; Sharp, A. J.; Schalkwyk, L. C.; Haroutunian, V.; Viechtbauer, W.; van den Hove, D.; Weedon, M. N.; Walter, J.; Coleman, P. D.; Bennett, D. A.; De Jager, P.; Mill, J.; Lunnon, K.

10.1101/2020.02.28.957894 — genomics — Posted on 2020-02-28

90 Genome wide association analysis in dilated cardiomyopathy reveals two new key players in systolic heart failure on chromosome 3p25.1 and 22q11.23

Garnier, S.; Harakalova, M.; Weiss, S.; Mokry, M.; Regitz-Zagrosek, V.; Hengstenberg, C.; Cappola, T. P.; Isnard, R.; Arbustini, E.; Cook, S. A.; van Setten, J.; Callis, J.; Hakonarson, H.; Morley, M. P.; Stark, K.; Prasad, S. K.; Li, J.; O'Regan, D. P.; Grasso, M.; Müller-Nurasyid, M.; Meitinger, T.; Empana, J.-P.; Strauch, K.; Waldenberger, M.; Marguiles, K. B.; Seidman, C. E.; Meder, B.; Boutouyrie, P.; Lacolley, P.; Jouven, X.; Erdman, J.; Blankenberg, S.; Wichter, T.; Ruppert, V.; Tavazzi, L.; Dubourg, O.; Roizes, G.; Dorent, R.; DeGroote, P.; Fauchier, L.; Trochu, J.-N.; Aupetit, J.-

10.1101/2020.02.28.969147 — genomics — Posted on 2020-02-28

91 Propylene glycol-based antifreeze as an effective preservative for DNA metabarcoding of benthic arthropods

Robinson, C. V.; Porter, T. M.; Wright, M. T. G.; Hajibabaei, M.

10.1101/2020.02.28.970475 — genomics — Posted on 2020-02-28

92 Body size and composition and site-specific cancers in UK Biobank: a Mendelian randomisation study

Vithayathil, M.; Carter, P.; Kar, S.; Mason, A.; Burgess, S.; Larsson, S.

10.1101/2020.02.28.970459 — genetics — Posted on 2020-02-28

93 Joint effects of host genotype and species arrival order govern plant microbiome composition and function

Leopold, D. R.; Busby, P. E.

10.1101/2020.02.28.970582 — ecology — Posted on 2020-02-28

94 High-content screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia

Lee, D. D. H.; Cardinale, D.; Nigro, E.; Butler, C. R.; Rutman, A.; Fassad, M. R.; Hirst, R. A.; Moulding, D.; Agrotis, A.; Forsythe, E.; Peckham, D.; Robson, E.; Smith, C. M.; Somavarapu, S.; Beales, P. L.; Hart, S. L.; Janes, S. M.; Mitchison, H. M.; Ketteler, R.; Hynds, R. E.; O'Callaghan, C.

10.1101/2020.02.28.959189 — cell biology — Posted on 2020-02-28

95 Tissue size controls patterns of cell proliferationand migration in freely-expanding epithelia

Heinrich, M. A.; LaChance, J.; Zajdel, T. J.; Alert, R.; Kosmrlj, A.; Cohen, D. J.

10.1101/2020.02.28.970418 — cell biology — Posted on 2020-02-28

96 Synthetic Agonist of Growth Hormone-Releasing Hormone as Novel Treatment for Heart Failure with Preserved Ejection Fraction

Dulce, R. A.; Kanashiro-Takeuchi, R. M.; Takeuchi, L. M.; Salerno, A. G.; Kulandavelu, S.; Balkan, W.; Zuttion, M. S.; Cai, R.; Schally, A. V.; Hare, J. M.

10.1101/2020.02.28.967000 — cell biology — Posted on 2020-02-28

97 Induced mutagenesis by the DNA cytosine deaminase APOBEC3H Haplotype I protects against lung cancer

Hix, M. A.; Wong, L.; Flath, B.; Chelico, L.; Cisneros, G. A.

10.1101/2020.02.28.970509 — biophysics — Posted on 2020-02-28

98 Future climate change promotes novel gene-climate associations in balsam poplar (Populus balsamifera L.), a forest tree species

Gougherty, A. V.; Keller, S. R.; Chhatre, V. E.; Fitzpatrick, M. C.

10.1101/2020.02.28.961060 — ecology — Posted on 2020-02-28

99 Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex

Maynard, K. E.; Collado-Torres, L.; Weber, L. M.; Uytingco, C.; Barry, B. K.; Williams, S. R.; Catallini, J. L.; Tran, M. N.; Besich, Z.; Tippani, M.; Chew, J.; Yin, Y.; Kleinman, J. E.; Hyde, T. M.; Rao, N.; Hicks, S. C.; Martinowich, K.; Jaffe, A. E.

10.1101/2020.02.28.969931 — neuroscience — Posted on 2020-02-28

100 Mass Photometry of Membrane Proteins

Olerinyova, A.; Sonn Segev, A.; Gault, J.; Eichmann, C.; Schimpf, J.; Kopf, A. H.; Rudden, L. S. P.; Ashkinadze, D.; Bomba, R.; Greenwald, J.; Degiacomi, M. T.; Killian, J. A.; Friedrich, T.; Riek, R.; Struwe, W. B.; Kukura, P.

10.1101/2020.02.28.969287 — biophysics — Posted on 2020-02-28

101 Genetic factors outside the metabolic cluster for plastid-derived sesquiterpenes are required to pursue arthropod-resistant tomatoes

Therezan, R.; Kortbeek, R.; Vendemiatti, E.; Legarrea, S.; de Alencar, S. M.; Schuurink, R.; Bleeker, P.; Peres, L. E. P.

10.1101/2020.02.21.960112 — plant biology — Posted on 2020-02-28

102 Bidirectional sex-dependent regulation of α6 and β3 nicotinic acetylcholine receptors by protein kinase Cε

Moen, J. K.; DeBaker, M. C.; Myjack, J. E.; Wickman, K.; Lee, A. M.

10.1101/2020.02.27.966978 — neuroscience — Posted on 2020-02-28

103 Parent of origin gene expression in the bumblebee, Bombus terrestris, supports Haig's kinship theory for the evolution of genomic imprinting.

Marshall, H.; van Zweden, J. S.; Van Geystelen, A.; Benaets, K.; Wäckers, F.; Mallon, E. B.; Wenseleers, T.

10.1101/2020.01.17.909168 — evolutionary biology — Posted on 2020-02-28

104 Effective Biophysical Modeling of Cell Free Transcription and Translation Processes

Adhikari, A.; Vilkhovoy, M.; Vadhin, S.; Lim, H. E.; Varner, J.

10.1101/2020.02.25.964841 — systems biology — Posted on 2020-02-28

105 Building a Reference Transcriptome for the Hexaploid Hard Fescue Turfgrass (Festuca brevipila) Using a Combination of PacBio IsoSeq and Illumina Sequencing

Qiu, Y.; Yang, Y.; Hirsch, C. D.; Watkins, E.

10.1101/2020.02.26.966952 — plant biology — Posted on 2020-02-28

106 Private-public mappings in human prefrontal cortex

Bang, D.; Ershadmanesh, S.; Nili, H.; Fleming, S. M.

10.1101/2020.02.21.954305 — neuroscience — Posted on 2020-02-28

107 Investigating the effects of pre-stimulus cortical synchrony on behavior

van Es, M. W. J.; Gross, J.; Schoffelen, J.-M.

10.1101/2020.02.27.967463 — neuroscience — Posted on 2020-02-28

108 Transection of the ventral hippocampal commissure impairs spatial reference but not contextual or spatial working memory

Jordan, J.; Tong, Y.; Pytte, C.

10.1101/437491 — neuroscience — Posted on 2020-02-28

109 Dynamics of visual perceptual processing in freely behaving mice

You, W.-K.; Mysore, S. P.

10.1101/2020.02.20.958652 — neuroscience — Posted on 2020-02-28

110 The Pathogenicity of SARS-CoV-2 in hACE2 Transgenic Mice

Bao, L.; Deng, W.; Huang, B.; Gao, H.; Liu, J.; Ren, L.; Wei, Q.; Yu, P.; Xu, Y.; Qi, F.; Qu, Y.; Li, F.; Lv, Q.; Wang, W.; Xue, J.; Gong, S.; Liu, M.; Wang, G.; Wang, S.; Song, Z.; Zhao, L.; Liu, P.; Zhao, L.; Ye, F.; Wang, H.; Zhou, W.; Zhu, N.; Zhen, W.; Yu, H.; Zhang, X.; Guo, L.; Chen, L.; Wang, C.; Wang, Y.; Wang, X.; Xiao, Y.; Sun, Q.; Liu, H.; Zhu, F.; Ma, C.; Yan, L.; Yang, M.; Han, J.; Xu, W.; Tan, W.; Peng, X.; Jin, Q.; Wu, G.; Qin, C.

10.1101/2020.02.07.939389 — microbiology — Posted on 2020-02-28

111 Achieving symptom relief in patients with Myalgic encephalomyelitis by targeting the neuro-immune interface and inducing disease tolerance

Rodriguez, L. S.; Pou, C.; Tadepally, L.; Zhang, J.; Mugabo, C. H.; Wang, J.; Mikes, J.; Olin, A.; Chen, Y.; Rorbach, J.; Juto, J.-E.; Li, T.-Q.; Julin, P.; Brodin, P.

10.1101/2020.02.20.958249 — immunology — Posted on 2020-02-28

112 An Effective CTL Peptide Vaccine for Ebola Zaire Based on Survivors' CD8+ Targeting of a Particular Nucleocapsid Protein Epitope with Potential Implications for COVID-19 Vaccine Design

Herst, C. V.; Burkholz, S.; Sidney, J.; Sette, A.; Harris, P. E.; Massey, S.; Brasel, T.; Cunha-Neto, E.; Rosa, D. S.; Chao, W. C. H.; Carback, R. T.; Hodge, T.; Wang, L.; Ciotlos, S.; Lloyd, P.; Rubsamen, R. M.

10.1101/2020.02.25.963546 — immunology — Posted on 2020-02-28

113 In silico integration of thousands of epigenetic datasets into 707 cell type regulatory annotations improves the trans-ethnic portability of polygenic risk scores

Amariuta, T.; Ishigaki, K.; Sugishita, H.; Ohta, T.; Matsuda, K.; Murakami, Y.; Price, A. L.; Kawakami, E.; Terao, C.; Raychaudhuri, S.

10.1101/2020.02.21.959510 — genetics — Posted on 2020-02-28

114 Nutritional stress alone can control in vitro tumor formation and its invasive nature

Gayan, S.; Teli, A.; Nair, A.; Dey, T.

10.1101/2020.02.17.952234 — cancer biology — Posted on 2020-02-28

115 Quality control and processing of nascent RNA profiling data

Smith, J. P.; Dutta, A. B.; Sathyan, K. M.; Guertin, M. J.; Sheffield, N. C.

10.1101/2020.02.27.956110 — bioinformatics — Posted on 2020-02-28

116 Bayesian non-parametric clustering of single-cell mutation profiles

Borgsmueller, N.; Bonet, J.; Marass, F.; Gonzalez-Perez, A.; Lopez-Bigas, N.; Beerenwinkel, N.

10.1101/2020.01.15.907345 — bioinformatics — Posted on 2020-02-28

117 A GT-seq panel for walleye (Sander vitreus) provides a generalized workflow for efficient development and implementation of amplicon panels in non-model organisms.

Bootsma, M.; Gruenthal, K. M.; McKinney, G. J.; Simmons, L.; Miller, L.; Sass, G. G.; Larson, W. A.

10.1101/2020.02.13.948331 — genomics — Posted on 2020-02-28

118 Novel transformer networks for improved sequence labeling in genomics

Clauwaert, J.; Waegeman, W.

10.1101/836163 — genetics — Posted on 2020-02-28

119 Molecular evolution of luciferase diversified bioluminescent signals in sea fireflies

Hensley, N. M.; Ellis, E. A.; Leung, N. Y.; Coupart, J.; Mikhailovsky, A.; Taketa, D. A.; Tessler, M.; Gruber, D. F.; Mitani, Y.; De Tomaso, A. W.; Rivers, T. J.; Gerrish, G. A.; Torres, E.; Oakley, T. H.

10.1101/2020.01.23.917187 — evolutionary biology — Posted on 2020-02-28

120 Selective loss of diversity in doubled-haploid linesfrom European maize landraces

Zeitler, L.; Ross-Ibarra, J.; Stetter, M. G.

10.1101/817791 — evolutionary biology — Posted on 2020-02-28

121 AnnotatorJ: an ImageJ plugin to ease hand-annotation of cellular compartments

Hollandi, R.; Horvath, P.

10.1101/2020.02.27.968362 — bioinformatics — Posted on 2020-02-28

122 Collective sperm movements are shaped by post-copulatory sexual selection and phylogenetic history in Peromyscus mice

Hook, K. A.; Weber, W. D.; Fisher, H. S.

10.1101/2020.02.08.939975 — evolutionary biology — Posted on 2020-02-28

123 Species coexistence facilitated by intraspecific competition in a model for dryland vegetation patterns

Eigentler, L.

10.1101/2020.01.13.903179 — ecology — Posted on 2020-02-28

124 Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity

Gans, I.; Hartig, E. I.; Zhu, S.; Tilden, A. R.; Hutchins, L. N.; Maki, N. J.; Graber, J. H.; Coffman, J. A.

10.1101/863555 — developmental biology — Posted on 2020-02-28

125 Development of a high-throughput radial migration device

Oliver, C. R.; Little, A. C.; Westerhof, T. M.; Pathanjeli, P.; Yates, J. A.; Merajver, S. D.

10.1101/2020.01.31.928879 — bioengineering — Posted on 2020-02-28

126 The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties

Soman, A.; Liew, C. W.; Teo, H. L.; Berezhnoy, N. V.; Olieric, V.; Korolev, N.; Rhodes, D.; Nordenskioeld, L.

10.1101/2019.12.18.881755 — biochemistry — Posted on 2020-02-28

127 POU6F2 Positive Retinal Ganglion Cells a Novel Group of ON-OFF Directionally Selective Subtypes in the Mouse Retina.

Li, Y.; Wang, J.; King, R.; Geisert, E. E.

10.1101/2020.02.28.968503 — genetics — Posted on 2020-02-28

128 A novel Ataxin-3 knock-in mouse model mimics the human SCA3 disease phenotype including neuropathological, behavioral, and transcriptional abnormalities

Haas, E.; Incebacak, R. D.; Hentrich, T.; Maringer, Y.; Schmidt, T.; Zimmermann, F.; Casadei, N.; Mills, J. D.; Aronica, E.; Riess, O. H.; Schulze-Hentrich, J. M.; Huebener-Schmid, J.

10.1101/2020.02.28.968024 — neuroscience — Posted on 2020-02-28

129 More than a feeling: central amygdala mediates social transfer of information about proximity of danger

Andraka, K.; Kondrakiewicz, K.; Rojek-Sito, K.; Ziegart-Sadowska, K.; Meyza, K.; Nikolaev, T.; Hamed, A.; Kursa, M.; Wojcik, M.; Danielewski, K.; Wiatrowska, M.; Kublik, E.; Bekisz, M.; Lebitko, T.; Duque, D.; Jaworski, T.; Madej, H.; Konopka, W.; Boguszewski, P. M.; Knapska, E.

10.1101/2020.02.28.969113 — neuroscience — Posted on 2020-02-28

130 A Quantitative Sequencing Framework for Absolute Abundance Measurements of Mucosal and Lumenal Microbial Communities

Barlow, J. T.; Bogatyrev, S. R.; Ismagilov, R. F.

10.1101/2020.02.28.970087 — microbiology — Posted on 2020-02-28

131 Live-cell imaging of circadian clock protein dynamics in CRISPR-generated knock-in cells

Gabriel, C. H.; del Olmo, M.; Zehtabian, A.; Reischl, S.; van Dijk, H.; Koller, B.; Grudziecki, A.; Maier, B. U.; Ewers, H.; Herzel, H.; Granada, A. E.; Kramer, A.

10.1101/2020.02.28.967752 — cell biology — Posted on 2020-02-28

132 Comparative Gene Essentiality across the Bacterial Domain

Shaw, D.; Hermoso, T.; Lluch-Senar, M.; Serrano, L.

10.1101/2020.02.28.969238 — genomics — Posted on 2020-02-28

133 Multithreaded two-pass connected components labelling and particle analysis in ImageJ

Doube, M.

10.1101/2020.02.28.969139 — bioinformatics — Posted on 2020-02-28

134 Intraspecific variation in land use-related functional traits in Plantago lanceolata

Gaspar, B.; Bossdorf, O.; Parepa, M.

10.1101/2020.02.28.967521 — plant biology — Posted on 2020-02-28

135 PLZF is a new substrate of CRBN with thalidomide and 5-hydroxythalidomide

Yamanaka, S.; Murai, H.; Saito, D.; Abe, G.; Tokunaga, E.; Iwasaki, T.; Takahashi, H.; Takeda, H.; Suzuki, T.; Shibata, N.; Tamura, K.; Sawasaki, T.

10.1101/2020.02.28.969071 — pharmacology and toxicology — Posted on 2020-02-28

136 Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of CCN2.

Keenan, C.; Ramos-Mucci, L.; Kanakis, I.; Milner, P.; Leask, A.; Abraham, D.; Bou-Gharios, G.; Poulet, B.

10.1101/2020.02.28.969105 — pathology — Posted on 2020-02-28

137 Downward Gazing for Steadiness

Koren, Y.; Mairon, R.; Sofer, I.; Parmet, Y.; Ben-Shahar, O.; Bar-Haim, S.

10.1101/2020.02.28.969162 — neuroscience — Posted on 2020-02-28

138 In search of the RNA world on Mars

Mojarro, A.; Jin, L.; Szostak, J. W.; Head, J. W.; Zuber, M. T.

10.1101/2020.02.28.964486 — molecular biology — Posted on 2020-02-28

139 Biology and rearing of the cogongrass gall midge, Orseolia javanica Kieffer & Docters van Leeuwen-Reijnvaan (Diptera: Cecidomyiidae)

Hidayat, P.; Arini, ; Guntoro, D.; Takasu, K.; Overholt, W. A.

10.1101/2020.02.27.966499 — ecology — Posted on 2020-02-28

140 Predicting changes in protein thermostability upon point mutation with deep 3D convolutional neural networks

Li, B.; Yang, Y. T.; Capra, J. A.; Gerstein, M.

10.1101/2020.02.28.959874 — bioinformatics — Posted on 2020-02-28

141 Weak support for the abundant niche-centre hypothesis in North American birds

Dallas, T.; Pironon, S.; Santini, L.

10.1101/2020.02.27.968586 — ecology — Posted on 2020-02-28

142 Two particle picking procedures for filamentous proteins: SPHIRE-crYOLO filament mode and SPHIRE-STRIPER

Wagner, T.; Lusnig, L.; Pospich, S.; Stabrin, M.; Schönfeld, F.; Raunser, S.

10.1101/2020.02.28.969196 — biophysics — Posted on 2020-02-28

143 Study of the binding mechanism of dasatinib to c-Src kinase using an efficient molecular dynamics method

Sohraby, F.; Javaheri Moghadam, M.; Aliyar, M.; Aryapour, H.

10.1101/650440 — bioinformatics — Posted on 2020-02-28

144 Diffuse retro-reflective imaging for improved video tracking of mosquitoes at human baited bednets

Voloshin, V.; Kröner, C.; Seniya, C.; Murray, G. P. D.; Guy, A.; Towers, C. E.; McCall, P. J.; Towers, D. P.

10.1101/691949 — animal behavior and cognition — Posted on 2020-02-28

145 Bone morphogenetic protein signaling regulates Id1 mediated neural stem cell quiescence in the adult zebrafish brain via a phylogenetically conserved enhancer module

Zhang, G.; Ferg, M.; Lubke, L.; Takamiya, M.; Beil, T.; Gourain, V.; Diotel, N.; Strahle, U.; Rastegar, S.

10.1101/787804 — developmental biology — Posted on 2020-02-28

146 A probabilistic framework for decoding behavior from in vivo calcium imaging data

Etter, G.; Manseau, F.; Williams, S.

10.1101/827030 — neuroscience — Posted on 2020-02-28

147 An EEG investigation of the trial-by-trial updating of complex knowledge structures

Richter, F. R.

10.1101/805887 — neuroscience — Posted on 2020-02-28

148 Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes

Thom, C. S.; Voight, B. F.

10.1101/787333 — genetics — Posted on 2020-02-28

149 Phylogenomic approaches reveal how a climatic inversion and glacial refugia shape patterns of diversity in an African rain forest tree species

Helmstetter, A. J.; Amoussou, B. E. N.; Bethune, K.; Kandem, N. G.; Glele Kakai, R. L.; Sonke, B.; Couvreur, T. L. P.

10.1101/807727 — evolutionary biology — Posted on 2020-02-28

150 Immunization of mice with chimeric antigens displaying selected epitopes confers protection against intestinal colonization and renal damage caused by Shiga toxin-producing Escherichia coli (STEC).

Montero, D. A.; Del Canto, F.; Salazar, J. C.; Cespedes, S.; Cadiz, L.; Arenas-Salinas, M.; Reyes, J.; Onate, A.; Vidal, R. M.

10.1101/783829 — microbiology — Posted on 2020-02-28

151 Evolution of conserved noncoding sequences in Arabidopsis thaliana

Yocca, A.; Lu, Z.; Schmitz, R. J.; Freeling, M.; Edger, P.

10.1101/727669 — genomics — Posted on 2020-02-28

152 Probabilistic index models for testing differential expression in single cell RNA sequencing data

Assefa, A. T.; Vandesompele, J.; Thas, O.

10.1101/718668 — genomics — Posted on 2020-02-28

153 Discovering functional sequences with RELICS, an analysis method for tiling CRISPR screens

Fiaux, P. C.; Chen, H. V.; Chen, A. R.; Chen, P. B.; McVicker, G.

10.1101/687293 — bioinformatics — Posted on 2020-02-28

154 RSVdb: A comprehensive database of transcriptome RNA structure

Yu, H.; Zhang, Y.; Sun, Q.; Gao, H.; Tao, S.

10.1101/710236 — bioinformatics — Posted on 2020-02-28

155 mPFC Spindle Cycles Organize Sparse Thalamic Activation and Recently Active CA1 cells During non-REM Sleep

Varela, C.; Wilson, M. A.

10.1101/653436 — neuroscience — Posted on 2020-02-28

156 The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER-Golgi contact sites

Wakana, Y.; Hayashi, K.; Nemoto, T.; Watanabe, C.; Taoka, M.; Campelo, F.; Kumata, H.; Umemura, T.; Inoue, H.; Arasaki, K.; Tagaya, M.

10.1101/679936 — cell biology — Posted on 2020-02-28

157 Uneven missing data skews phylogenomic relationships within the lories and lorikeets

Smith, B. T.; Mauck, W. M.; Benz, B.; Andersen, M. J.

10.1101/398297 — evolutionary biology — Posted on 2020-02-28

158 When does gene flow facilitate evolutionary rescue?

Tomasini, M.; Peischl, S.

10.1101/622142 — evolutionary biology — Posted on 2020-02-28

159 Within and cross species predictions of plant specialized metabolism genes using transfer learning

Moore, B. M.; Wang, P.; Fan, P.; Lee, A.; Leong, B.; Lou, Y.-L.; Schenck, C. A.; Sugimoto, K.; Last, R.; Lehti-Shiu, M. D.; Barry, C.; Shiu, S.-H.

10.1101/2020.01.13.112102 — plant biology — Posted on 2020-02-28

160 Task-induced neural covariability as a signature of approximate Bayesian learning and inference

Lange, R. D.; Haefner, R. M.

10.1101/081661 — neuroscience — Posted on 2020-02-28

161 Extreme rainfall event drives early onset cyanobacterial bloom

Larsen, M. L.; Baulch, H. M.; Schiff, S. L.; Simon, D. F.; Sauve, S.; Venkiteswaran, J. J.

10.1101/570275 — ecology — Posted on 2020-02-28

162 Gut Microbiome Pattern Reflects Healthy Aging and Predicts Extended Survival in Humans

Wilmanski, T.; Diener, C.; Rappaport, N.; Patwardhan, S.; Wiedrick, J.; Lapidus, J.; Earls, J. C.; Zimmer, A.; Glusman, G.; Robinson, M.; Yurkovich, J. T.; Kado, D. M.; Cauley, J. A.; Zmuda, J.; Lane, N. E.; Magis, A. T.; Lovejoy, J. C.; Gibbons, S. M.; Hood, L.; Orwoll, E. S.; Price, N. D.

10.1101/2020.02.26.966747 — systems biology — Posted on 2020-02-28

163 Representing Organic Matter Thermodynamics in Biogeochemical Reactions via Substrate-Explicit Modeling

Song, H.-S.; Stegen, J. C.; Graham, E. B.; Lee, J.-Y.; Garayburu-Caruso, V.; Nelson, W. C.; Chen, X.; Moulton, J. D.; Scheibe, T. D.

10.1101/2020.02.27.968669 — systems biology — Posted on 2020-02-28

164 Dynamic modulation of glucose utilisation by glucocorticoid rhythms in health and disease

Zavala, E.; Gil-Gomez, C. A.; Wedgwood, K. C.; Burgess, R.; Tsaneva-Atanasova, K.; Herrera-Valdez, M. A.

10.1101/2020.02.27.968354 — systems biology — Posted on 2020-02-28

165 Bacterial Community Composition and Diversity along the Southern Coastlines of the Atlantic Ocean in Cape Town, South Africa

Olapade, O. A.

10.1101/2020.02.27.969030 — microbiology — Posted on 2020-02-28

166 Fast, Rate-Independent, Finite Element Implementation of a 3D Constrained Mixture Model of Soft Tissue Growth and Remodeling

Latorre, M.; Humphrey, J. D.

10.1101/2020.02.27.968768 — bioengineering — Posted on 2020-02-28

167 A benchmark of protein solubility prediction methods on UDP-dependent glycosyltransferases

Ashari Ghomi, F.; Kittila, T.; Welner, D. H.

10.1101/2020.02.28.962894 — biochemistry — Posted on 2020-02-28

168 Spiking neural network model of motor cortex with joint excitatory and inhibitory clusters reflects task uncertainty, reaction times, and variability dynamics

Rostami, V.; Rost, T.; Riehle, A.; van Albada, S. J.; P. Nawrot, M.

10.1101/2020.02.27.968339 — neuroscience — Posted on 2020-02-28

169 Exploring a natural baseline for large herbivore biomass

Floejgaard, C.; Pedersen, P. B. M.; Sandom, C.; Svenning, J.-C.; Ejrnaes, R.

10.1101/2020.02.27.968461 — ecology — Posted on 2020-02-28

170 Molecular goniometers for single-particle cryo-EM of DNA-binding proteins

Aksel, T.; Yu, Z.; Cheng, Y.; Douglas, S. M.

10.1101/2020.02.27.968883 — biophysics — Posted on 2020-02-28

171 Learning prediction error neurons in a canonical interneuron circuit

Hertäg, L.; Sprekeler, H.

10.1101/2020.02.27.968776 — neuroscience — Posted on 2020-02-28

172 Alternative splicing of COQ-2 determines the choice between ubiquinone and rhodoquinone biosynthesis in helminths

Tan, J. H.; Lautens, M.; Laura Romanelli-Cedrez, L.; Wang, J.; Schertzberg, M. R.; Reinl, S. R.; Davis, R. E.; Shepherd, J. N.; Salinas, G.; Fraser, A.

10.1101/2020.02.28.965087 — molecular biology — Posted on 2020-02-28

173 Deep-sea corals near cold seeps associate with chemoautotrophic bacteria that are related to the symbionts of cold seep and hydrothermal vent mussels.

Vohsen, S. A.; Gruber-Vodicka, H. R.; Osman, E. O.; Saxton, M. A.; Joye, S. B.; Dubilier, N.; Fisher, C. R.; Baums, I. B.

10.1101/2020.02.27.968453 — microbiology — Posted on 2020-02-28

174 S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling

Geng, X.; Yanagida, K.; Akwii, R.; Choi, D.; Chen, L.; Ho, Y.; Cha, B.; Mahamud, M. R.; de Ruiz, K. B.; Ichise, H.; Chen, H.; Wythe, J.; Hong, Y.-K.; Mikelis, C.; Hla, T.; Srinivasan, R. S.

10.1101/2020.02.27.968594 — developmental biology — Posted on 2020-02-28

175 The serine-threonine kinase TAO3 promotes cancer invasion and tumor growth by facilitating trafficking of endosomes containing the invadopodia scaffold TKS5α

Iizuka, S.; Quintavalle, M.; Ceja Navarro, J.; Gribbin, K. P.; Ardecky, R. J.; Abelman, M.; Ma, C.-T.; Sergienko, E.; Zeng, F.-Y.; Pass, I.; Thomas, G.; McWeeney, S.; Hassig, C. A.; Pinkerton, A. B.; Courtneidge, S. A.

10.1101/2020.02.27.968305 — cancer biology — Posted on 2020-02-28

176 Elevated soluble Galectin-3 as a marker of chemotherapy efficacy in Breast cancer patients: a prospective study

Shafiq, A.; Moore, J.; Suleman, A.; Faiz, S.; Farooq, O.; Arshad, A.; Tehseen, M.; Zaffar, A.; Ali, S. H.; Din, N. U.; Loya, A.; Siddiqui, N.; Rehman, F. K.

10.1101/2020.02.27.968073 — cancer biology — Posted on 2020-02-28

177 Amalgams: data-driven amalgamation for the reference-free dimensionality reduction of zero-laden compositional data

Quinn, T.; Erb, I.

10.1101/2020.02.27.968677 — bioinformatics — Posted on 2020-02-28

178 Automated measurement of long-term bower behaviors in Lake Malawi cichlids using depth sensing and action recognition

Johnson, Z. V.; Long, L.; Li, J.; Arrojwala, M. T. S.; Aljapur, V.; Lee, T.; Lowder, M. C.; Gu, K.; Lancaster, T. J.; Stockert, J. I.; Moorman, J. M.; Lecesne, R. L.; Streelman, J. T.; McGrath, P. T.

10.1101/2020.02.27.968511 — animal behavior and cognition — Posted on 2020-02-28

179 In vivo Feedback Control of an Antithetic Molecular-Titration Motif in Escherichia coli using Microfluidics

Di Bernardo, M.; Shannon, B.; Zamora, C.; Postiglione, L.; Salzano, D.; Grierson, C.; Marucci, L.; Savery, N. J.

10.1101/2020.02.28.952143 — synthetic biology — Posted on 2020-02-28

180 Dispersion of functional gradients across the lifespan

Bethlehem, R. A. I.; Paquola, C.; Ronan, L.; Seidlitz, J.; Bernhardt, B.; Tsvetanov, K. A.

10.1101/2020.02.27.968537 — neuroscience — Posted on 2020-02-28

181 Distinct organization of two cortico-cortical feedback pathways

Shen, S.; Jiang, X.; Scala, F.; Fu, J.; Fahey, P.; Kobak, D.; Tan, Z.; Reimer, J.; Sinz, F. H.; Tolias, A.

10.1101/2020.02.27.968792 — neuroscience — Posted on 2020-02-28

182 Prefrontal responses during proactive and reactive inhibition are differentially impacted by stress in anorexia and bulimia nervosa

Westwater, M. L.; Mancini, F.; Gorka, A. X.; Shapleske, J.; Serfontein, J.; Grillon, C.; Ernst, M.; Ziauddeen, H.; Fletcher, P. C.

10.1101/2020.02.27.968719 — neuroscience — Posted on 2020-02-28

183 Deficits in olfactory sensitivity in a mouse model of Parkinson's disease revealed by plethysmography of odor-evoked sniffing

Johnson, M. E.; Bergkvist, L.; Mercado, G.; Stertzik, L.; Meyerdirk, L.; Brundin, P.; Wesson, D. W.

10.1101/2020.02.27.968545 — neuroscience — Posted on 2020-02-28

184 Genome wide-association study identifies novel loci in the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study

Gudiseva, H. V.; Verma, S. S.; Chavali, V. R. M.; Salowe, R.; Lucas, A.; Collins, D. W.; Rathi, S.; He, J.; Lee, R.; Merriam, S.; Bowman, A. S.; mchugh, c. p.; Zody, M. C.; Pistilli, M.; Khachatryan, N.; Ebenezer, D.; Windell, M.; Weiner, M.; Henderer, J.; Ross, A.; Cui, Q. N.; Addis, V.; Lehman, A.; Miller-Ellis, E.; Sankar, P.; Varma, R.; Williams, S. M.; Ying, G.-S.; Moore, J. H.; Ritchie, M. D.; O'Brien, J. M.

10.1101/2020.02.27.968156 — genetics — Posted on 2020-02-28

185 Many but not all lineage-specific genes can be explained by homology detection failure

Weisman, C. M.; Murray, A. W.; Eddy, S. R.

10.1101/2020.02.27.968420 — evolutionary biology — Posted on 2020-02-28

186 SAFE Acoustics: an open-source, real-time eco-acoustic monitoring network in the tropical rainforests of Borneo

Sethi, S. S.; Ewers, R. M.; Jones, N. S.; Signorelli, A.; Picinali, L.; Orme, C. D. L.

10.1101/2020.02.27.968867 — ecology — Posted on 2020-02-28

187 Identification of potential biomarkers in subtypes of epithelial ovarian cancer

Singh, R.; Som, A.

10.1101/2020.02.24.962472 — bioinformatics — Posted on 2020-02-28

188 Molecular profiling of lipid droplets inside HuH7 Cells with Raman micro-spectroscopy

Samuel, A. Z.; Miyaoka, R.; Ando, M.; Gaebler, A.; Thiele, C.; Takeyama, H.

10.1101/2020.02.27.968701 — bioengineering — Posted on 2020-02-28

189 New environment, new invaders - repeated horizontal transfer of LINEs to sea snakes

Galbraith, J. D.; Luddington, A. J.; Suh, A. L.; Sanders, K. L.; Adelson, D. L.

10.1101/2020.02.27.968685 — evolutionary biology — Posted on 2020-02-28

190 Candidate stress biomarkers for queen failure diagnostics

McAfee, A.; Milone, J. P.; Chapman, A. A.; Foster, L. J.; Tarpy, D. R.; Pettis, J.

10.1101/2020.02.27.961847 — biochemistry — Posted on 2020-02-28

191 Simultaneous auditory agnosia: Systematic description of a new type of auditory segregation deficit following a right hemisphere lesion

Holmes, E.; Utoomprurkporn, N.; Hoskote, C.; Warren, J.; Bamiou, D.-E.; Griffiths, T. D.

10.1101/2020.02.27.968107 — neuroscience — Posted on 2020-02-28

192 Decomposing Loss Aversion from Gaze Allocation and Pupil Dilation

Sheng, F.; Ramakrishnan, A.; Darsol, S.; Cen, P.; Zhao, W. J.; Thelaus, S.; Platt, M.

10.1101/2020.02.27.967711 — neuroscience — Posted on 2020-02-28

193 Temporal dynamics of visual representations in the infant brain

Bayet, L.; Zinszer, B. D.; Reilly, E.; Cataldo, J. K.; Pruitt, Z.; Cichy, R. M.; Nelson, C. A.; Aslin, R. N.

10.1101/2020.02.26.947911 — neuroscience — Posted on 2020-02-28

194 Seizure onset location shapes dynamics of initiation

Salami, P.; Peled, N.; Nadalin, J. K.; Martinet, L.-E.; Kramer, M.; Lee, J. W.; Cash, S. S.

10.1101/2020.02.27.968313 — neuroscience — Posted on 2020-02-28

195 Designing membrane-reshaping nanostructures through artificial evolution

Forster, J. C.; Krausser, J.; Vuyyuru, M. R.; Baum, B.; Saric, A.

10.1101/2020.02.27.968149 — biophysics — Posted on 2020-02-28

196 Repeated morphine exposure activates synaptogenesis and other neuroplasticity-related gene networks in the prefrontal cortex of male and female rats

Liu, S. X.; Gades, M. S.; Harris, A. H.; Tran, P. V.; Gewirtz, J. C.

10.1101/2020.02.26.966416 — neuroscience — Posted on 2020-02-28

197 Propagation of Hippocampal Ripples to the Neocortex by Way of a Subiculum-Retrosplenial Pathway

Nitzan, N.; McKenzie, S.; Sanker Beed, P.; Fine English, D.; Oldani, S.; Jan Tukker, J.; Buzsaki, G.; Schmitz, D.

10.1101/2020.02.27.966770 — neuroscience — Posted on 2020-02-28

198 Recovery plans need better science to support decisions that allow species to decline in abundance but be recovered

Li, Y.-W.; Malcom, J. W.; Che-Castaldo, J.; Neel, M.

10.1101/2020.02.27.966101 — ecology — Posted on 2020-02-28

199 Sequence-based Prediction of Metamorphic Behavior in Proteins

Chen, N.; Das, M.; Liwang, A.; Wang, L.-P.

10.1101/2020.02.27.967935 — biophysics — Posted on 2020-02-28

200 Alteration of brain dynamics during natural dual-task walking

Nenna, F.; Do, C. T.; Protzak, J.; Gramann, K.

10.1101/2020.02.27.968164 — neuroscience — Posted on 2020-02-28

201 A Bayesian inference tool for identifying artifactual calls from differential transcript abundance analyses

Mangiola, S.; Modrak, M.; Thomas, E.; Papenfuss, A. T.

10.1101/2020.02.27.967240 — bioinformatics — Posted on 2020-02-28

202 Biosonar spatial resolution along the distance axis: revisiting the clutter interference zone

Wagenhäuser, P. A.; Wiegrebe, L.; Baier, A. L.

10.1101/2020.02.27.967919 — animal behavior and cognition — Posted on 2020-02-28

203 Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex

Jamann, N.; Dannehl, D.; Wagener, R.; Corcelli, C.; Schultz, C.; Staiger, J.; Kole, M. H. P.; Engelhardt, M.

10.1101/2020.02.27.968065 — neuroscience — Posted on 2020-02-28

204 Bacterial immune evasion proteins: The therapeutic potential of CHIPS

Tromp, A.; Zhao, Y.; Jongerius, I.; Heezius, E. C.; Abrial, P.; Ruyken, M.; van Strijp, J.; de Haas, C. J. C.; Spaan, A.; van Kessel, K. P. M.; Henry, T.; Haas, P.-J. A.

10.1101/2020.02.25.964908 — microbiology — Posted on 2020-02-28

205 Interferon-induced Protein-44 and Interferon-induced Protein 44-like restrict replication of Respiratory Syncytial Virus

Busse, D. C.; Habgood-Coote, D.; Clare, S.; Brandt, C.; Bassano, I.; Kafarou, M.; Herberg, J.; Levin, M.; Eleouet, J.-F.; Kellam, P.; Tregoning, J. S.

10.1101/2020.02.24.963900 — immunology — Posted on 2020-02-28

206 Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

Krebs, K.; Bovijn, J.; Lepamets, M.; Censin, J. C.; Jurgenson, T.; Sarg, D.; Luo, Y.; Skotte, L.; Geller, F.; Feenstra, B.; Wang, W.; Auton, A.; 23andMe Research Team, ; Raychaudhuri, S.; Esko, T.; Metspalu, A.; Laur, S.; Holmes, M. V.; Lindgren, C. M.; Magi, R.; Milani, L.; Fadista, J.

10.1101/2020.02.27.967497 — genetics — Posted on 2020-02-28

207 Prediction of receptorome for human-infecting virome

Zhang, Z.; Ye, S.; Wu, A.; Jiang, T.; Peng, Y.

10.1101/2020.02.27.967885 — bioinformatics — Posted on 2020-02-28

208 Brassinosteroids Suppress Ethylene Biosynthesis via Transcription Factor BZR1 in Pear and Apple Fruit

Ji, Y.; Qu, Y.; Jiang, Z.; Su, X.; Yue, P.; Li, X.; Wang, Y.; Bu, H.; Yuan, H.; Wang, A.

10.1101/2020.02.27.968800 — plant biology — Posted on 2020-02-28

209 Data-driven polymer model for mechanistic exploration of diploid genome organization

Qi, Y.; Reyes, A.; Johnstone, S. E.; Aryee, M. J.; Bernstein, B. E.; Zhang, B.

10.1101/2020.02.27.968735 — biophysics — Posted on 2020-02-28

210 BAMBARA GROUNDNUT RHIZOBACTERIA ANTIMICROBIAL AND BIOFERTILIZATION POTENTIAL

Ajilogba, C. F.; Babalola, O. O.; Adebola, P.; Adeleke, R.

10.1101/2020.02.27.964346 — molecular biology — Posted on 2020-02-28

211 Diversity and Distribution of a Novel Genus of Hyperthermophilic Aquificae Viruses Encoding a Proof-reading Family-A DNA Polymerase

Palmer, M.; Hedlund, B. P.; Roux, S.; Tsourkas, P.; Doss, R. K.; Stamereilers, C.; Mehta, A.; Dodsworth, J. A.; Lodes, M.; Monsma, S.; Glavina del Rio, T.; Schoenfeld, T. W.; Eloe-Fadrosh, E. A.; Mead, D. A.

10.1101/2020.02.27.968263 — microbiology — Posted on 2020-02-28

212 Microbiome shifts associated with the introduction of wild Atlantic horseshoe crabs (Limulus polyphemus) into a touch-tank exhibit

Friel, A. D.; Neiswenter, S. A.; Seymour, C. O.; Bali, L. R.; McNamara, G.; Leija, F.; Jewell, J.; Hedlund, B. P.

10.1101/2020.02.27.968784 — microbiology — Posted on 2020-02-28

213 Colonization with the commensal fungus Candida albicans perturbs the gut-brain axis through dysregulation of endocannabinoid signaling

Kumamoto, C.; Markey, L.; Maguire, J.; Hooper, A.; Melon, L.; Baglot, S.; Hill, M. N.

10.1101/2020.02.27.968198 — microbiology — Posted on 2020-02-28

214 Phylogenomic analysis of Clostridiodes difficile ribotype 106 strains reveals novel genetic islands and emergent phenotypes

Roxas, B. A. P.; Roxas, J. L.; Claus-Walker, R.; Harishankar, A.; Mansoor, A.; Anwar, F.; Jillella, S.; Williams, A.; Lindsey, J.; Elliott, S. P.; Shehab, K. W.; Viswanathan, V. K.; Vedantam, G.

10.1101/2020.02.27.968479 — genomics — Posted on 2020-02-28

215 Evolution of genome structure in the Drosophila simulans species complex

Chakraborty, M.; Chang, C.-H.; Khost, D.; Vedanayagam, J.; Adrion, J. R.; Liao, Y.; Montooth, K. L.; Meiklejohn, C. D.; Larracuente, A. M.; Emerson, J. J.

10.1101/2020.02.27.968743 — genomics — Posted on 2020-02-28

216 Mechanisms preventing Break-Induced Replication during repair of two-ended DNA double-strand breaks

Ira, G.; Pham, N.; Yan, Z.; Haber, J. E.; Malkova, A.

10.1101/2020.02.28.969154 — genetics — Posted on 2020-02-28

217 Differential glycosylation of alpha-1-acid glycoprotein (AGP-1) contributes to its functional diversity.

Sumanth, M. S.; Jacob, S. P.; Abhilasha, K. V.; Manne, B. K.; Basrur, V.; Lehoux, S. D.; Campbell, R. A.; Yost, C. C.; T. Rondina, M.; McIntyre, T. M.; Cummings, R. D.; Weyrich, A. S.; Marathe, G. K.

10.1101/2020.02.27.968974 — biochemistry — Posted on 2020-02-28

218 Nanobody-dependent delocalization of endocytic machinery in Arabidopsis root cells dampens their internalization capacity

Winkler, J.; De Meyer, A.; Mylle, E.; Grones, P.; Van Damme, D.

10.1101/2020.02.27.968446 — cell biology — Posted on 2020-02-28

219 Dose-dependent phorbol 12-myristate-13-acetate-1 mediated monocyte-to-macrophage differentiation induces unique proteomic signatures in THP-1 cells

Pinto, S.; Kim, H.; Subbannayya, Y.; Giambelluca, M.; Boesl, K.; Kandasamy, R. K.

10.1101/2020.02.27.968016 — immunology — Posted on 2020-02-28

220 Genomic copy number predicts oesophageal cancer years before transformation

Killcoyne, S.; Gregson, E.; Wedge, D. C.; Woodcock, D. J.; Eldridge, M.; de la Rue, R.; Miremadi, A.; Abbas, S.; Blasko, A.; Januszewicz, W.; Jenkins, A. V.; Gerstung, M.; Fitzgerald, R. C.

10.1101/2020.02.27.967612 — genomics — Posted on 2020-02-28

221 Structure-guided DNA-DNA attraction mediated by divalent cations

Srivastava, A.; Timsina, R.; Heo, S.; Dewage, S. W.; Kirmizialtin, S.; Qui, X.

10.1101/2020.02.27.968982 — biophysics — Posted on 2020-02-28

222 brt: An R package for integrating biological relevance with p value in omics data

Zheng, L.; Li, J.; Yu, P.

10.1101/2020.02.27.968909 — bioinformatics — Posted on 2020-02-28

223 JACKIE: Fast enumeration of single- and multi-copy CRISPR binding sites

Zhu, J. J.; Cheng, A. W.

10.1101/2020.02.27.968933 — bioinformatics — Posted on 2020-02-28

224 Jekyll or Hyde? The genome (and more) of Nesidiocoris tenuis, a zoophytophagous predatory bug that is both a biological control agent and a pest

Ferguson, K. B.; Visser, S.; Dalikova, M.; Provaznikova, I.; Urbaneja, A.; Perez-Hedo, M.; Marec, F.; Werren, J.; Zwaan, B. J.; Pannebakker, B. A.; Verhulst, E. C.

10.1101/2020.02.27.967943 — genomics — Posted on 2020-02-28

225 FL-QSAR: a federated learning based QSAR prototype for collaborative drug discovery

Chen, S.; Xue, D.; Chuai, G.; Yang, Q.; Liu, Q.

10.1101/2020.02.27.950592 — bioinformatics — Posted on 2020-02-28

226 Cellular and structural basis of synthesis of the unique intermediate dehydro-F420-0 in mycobacteria

Grinter, R.; Ney, B.; Brammananth, R.; Barlow, C. K.; Cordero, P. R. F.; Gillett, D. L.; Izore, T.; Cryle, M.; Harold, L.; Cook, G. M.; Taiaroa, G.; Williamson, D. A.; Warren, A. C.; Oakshott, J. G.; Taylor, M. C.; Crellin, P. K.; Jackson, C. J.; Schittenhelm, R. B.; Coppel, R. L.; Greening, C.

10.1101/2020.02.27.968891 — biochemistry — Posted on 2020-02-28

227 MicroRNA clusters integrate evolutionary constraints on expression and target affinities: the miR-6/5/4/286/3/309 cluster in Drosophila leg development

Qu, Z.; Yiu, W. C.; Yip, H. Y.; Nong, W.; Yu, C. W. C.; Lee, I. H. T.; Wong, A. Y. P.; Wong, N. W. Y.; Cheung, F. K. M.; Chan, T. F.; Lau, K. F.; Zhong, S.; Chu, K. H.; Tobe, S. S.; Ferrier, D. E. K.; Bendena, W. G.; Hui, J. H. L.

10.1101/714766 — evolutionary biology — Posted on 2020-02-28

228 Evolutionary dynamics and diversification in changing environments

Alekseeva, E.; Ispolatov, I.; Doebeli, M.

10.1101/590406 — biophysics — Posted on 2020-02-28

229 Differential Synaptic Input to External Globus Pallidus Neuronal Subpopulations In Vivo.

Silberberg, G.; Ketzef, M.

10.1101/2020.02.27.967869 — neuroscience — Posted on 2020-02-28

230 Quantification of Adeno-Associated Virus with Safe Nucleic Acid Dyes

Xu, J.; DeVries, S.; Zhu, Y.

10.1101/2020.02.27.968636 — molecular biology — Posted on 2020-02-28

231 Gut Microbiome Profiling of a Rural and Urban South African Cohort Reveals Biomarkers of a Population in Lifestyle Transition

Oduaran, O. H.; Tamburini, F. B.; Sahibdeen, V.; Brewster, R.; Gomez-Olive, F. X.; Kahn, K.; Norris, S. A.; Tollman, S. M.; Twine, R.; Wade, A. N.; Wagner, R. G.; Lombard, Z.; Bhatt, A. S.; Hazelhurst, S.

10.1101/2020.02.27.964023 — microbiology — Posted on 2020-02-28

232 Microbial grazers can control chytridiomycosis caused by aquatic zoosporic fungi

Farthing, H. N.; Jiang, J.; Henwood, A. J.; Fenton, A.; Garner, T. W. J.; Daversa, D. R.; Fisher, M. C.; Montagnes, D. J. S.

10.1101/2020.02.03.931857 — microbiology — Posted on 2020-02-28

233 Iterative Hard Thresholding in GWAS: Generalized Linear Models, Prior Weights, and Double Sparsity

Chu, B. B.; Keys, K. L.; German, C. A.; Zhou, H.; Zhou, J. J.; Sobel, E.; Sinsheimer, J. S.; Lange, K.

10.1101/697755 — genomics — Posted on 2020-02-28

234 Dampened PI3K/AKT signaling contributes to cancer resistance of the naked mole rat

Zhao, J.; Tian, X.; Zhu, Y.; Zhang, Z.; Rydkina, E.; Yuan, Y.; Zhang, H.; Roy, B.; Cornwell, A.; Nevo, E.; Shang, X.; Huang, R.; Kristiansen, K.; Seluanov, A.; Fang, X.; Gorbunova, V.

10.1101/2020.02.27.967729 — cancer biology — Posted on 2020-02-28

He, Z.; Brazovskaja, A.; Ebert, S.; Camp, G.; Treutlein, B.

10.1101/2020.02.27.968560 — bioinformatics — Posted on 2020-02-28

236 Mapping Spatially Distributed Material Properties in Finite Element Models of Plant Tissue Using Computed Tomography

Stubbs, C. J.; Larson, R.; Cook, D. D.

10.1101/2020.02.27.968651 — bioengineering — Posted on 2020-02-28

237 The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities

Herbert, E.; Stewart, M. E.; Hutchison, M.; Flenniken, A.; Qu, D.; Nutter, L.; Mckerlie, C.; Hobson, L.; Kick, B.; Lyons, B.; Wiegand, J.-P.; Doty, R.; Aguilar-Pimentel, J. A.; Hrabe de Angelis, M.; Dickinson, M.; Seavitt, J.; White, J.; Scudamore, C.; Wells, S.

10.1101/2020.02.25.964254 — genetics — Posted on 2020-02-28

238 Limited evolution despite years of measurable viremia in a cART-treated seronegative HIV-1 positive individual

Fryer, H. R.; Raghwani, J.; Gill, M. J.; van Marle, G.; Golubchi, T.; Grove, J.; Lythgoe, K.

10.1101/2020.02.20.957274 — evolutionary biology — Posted on 2020-02-28

239 Identifying density-dependent interactions in collective cell behaviour

Browning, A. P.; Jin, W.; Plank, M. J.; Simpson, M. J.

10.1101/811257 — cell biology — Posted on 2020-02-28

240 Building a Reference Transcriptome for the Hexaploid Hard Fescue Turfgrass (Festuca brevipila) Using a Combination of PacBio IsoSeq and Illumina Sequencing

Qiu, Y.; Yang, Y.; Hirsch, C. D.; Watkins, E.

10.1101/2020.02.26.966952 — plant biology — Posted on 2020-02-28

241 Artificial diets modulate infection rates of bumblebees by Nosema ceranae

Gomez-Moracho, T.; Durand, T.; Pasquaretta, C.; Heeb, P.; Lihoreau, M.

10.1101/2020.02.27.967455 — physiology — Posted on 2020-02-28

242 Bidirectional sex-dependent regulation of α6 and β3 nicotinic acetylcholine receptors by protein kinase Cε

Moen, J. K.; DeBaker, M. C.; Myjack, J. E.; Wickman, K.; Lee, A. M.

10.1101/2020.02.27.966978 — neuroscience — Posted on 2020-02-28

243 Flexible annotation atlas of the mouse brain: combining and dividing brain structures of the Allen Brain Atlas while maintaining anatomical hierarchy

Takata, N.; Sato, N.; Komaki, Y.; Okano, H.; Tanaka, K. F.

10.1101/2020.02.17.953547 — neuroscience — Posted on 2020-02-28

244 Brain disconnections link structural connectivity with function and behaviour

Thiebaut de Schotten, M.; Foulon, C.; Nachev, P.

10.1101/2020.02.27.967570 — neuroscience — Posted on 2020-02-28

245 Phage-Antibiotic Synergy Is Driven By A Unique Combination Of Antibacterial Mechanism Of Action And Stoichiometry

Gu Liu, C.; Green, S. I.; Min, L.; Clark, J. R.; Salazar, K. C.; Terwilliger, A. L.; Kaplan, H.; Trautner, B.; Ramig, R. F.; Maresso, A. W.

10.1101/2020.02.27.967034 — microbiology — Posted on 2020-02-28

246 On the effects of climate change on Galapagos green turtle Chelonia mydas agassizii neonate mortality in A1B

Gotts, M. J.

10.1101/2020.02.27.968628 — ecology — Posted on 2020-02-28

247 TIRAP drives myelosuppression through an Ifnγ-Hmgb1 axis that disrupts the marrow microenvironment

Ibrahim, R.; Gopal, A.; Fuller, M.; Umlandt, P.; Chang, L.; Wegrzyn-Woltosz, J.; Lam, J.; Li, J.; Lu, M.; Parker, J.; Karsan, A.

10.1101/2020.02.26.967018 — cancer biology — Posted on 2020-02-28

248 Joint profiling of proteins and DNA in single cells reveals extensive proteogenomic decoupling in leukemia

Demaree, B.; Delley, C. L.; Vasudevan, H. N.; Peretz, C. A. C.; Ruff, D.; Smith, C. C.; Abate, A. R.

10.1101/2020.02.26.967133 — cancer biology — Posted on 2020-02-28

249 Subphase Material Stabilizes Films of Pulmonary Surfactant

Andreev, K.; Martynowycz, M.; Kuzmenko, I.; Bu, W.; Hall, S. B.; Gidalevitz, D.

10.1101/2020.02.27.968099 — biophysics — Posted on 2020-02-28

250 Invariance of neural representations cannot be validly inferred from neuroimaging decoding studies: Empirical and computational evidence

Narasiwodejar, S.; Soto, F. A.

10.1101/2020.02.27.967505 — neuroscience — Posted on 2020-02-28

251 RNA-protein interaction mapping via MS2 or Cas13-based APEX targeting

Han, S.; Zhao, B. S.; Myers, S. A.; Carr, S. A.; He, C.; Ting, A. Y.

10.1101/2020.02.27.968297 — molecular biology — Posted on 2020-02-28

252 Exposure to Mites Sensitizes Intestinal Stem Cell Maintenance, Splenic Marginal Zone B Cell Homeostasis, And Heart Development to Notch Dosage and Cooperativity.

Kobia, F. M.; Preusse, K.; Dai, Q.; Weaver, N.; Stein, S. J.; Pear, W.; Yuan, Z.; Kovall, R.; Kuang, Y.; Eafergen, N.; Sprinzak, D.; Gebelein, B.; Brunskill, E. W.; Kopan, R.

10.1101/2020.02.13.948224 — developmental biology — Posted on 2020-02-28

253 Model of ciprofloxacin subdiffusion in Pseudomonas aeruginosa biofilm formed in artificial sputum medium

Kosztołowicz, T.; Metzler, R.; Wasik, S.; Arabski, M.

10.1101/2020.02.26.966507 — biophysics — Posted on 2020-02-28

254 Using karyotyping and achene morphology to accurately identify Sonchus oleraceus (Asteraceae) in the context of its biological control

Ollivier, M.; Gauthier, P.; Lesieur, V.; Thomann, T.; Jourdan, M.; Bon, M.-C.; Sheppard, A.; Raghu, S.; Tixier, M.-S.; Martin, J.-F.

10.1101/2020.02.26.965863 — plant biology — Posted on 2020-02-28

255 Paired high-throughput, in-situ imaging and high-throughput sequencing illuminate acantharian abundance and vertical distribution

Mars Brisbin, M.; Brunner, O. D.; Mitarai, S.

10.1101/2020.02.27.967349 — microbiology — Posted on 2020-02-28

256 Fibroblastic reticular cells predict response to immune checkpoint inhibitors

Biasci, D.; Thaventhiran, J.; Tavare, S.

10.1101/2020.02.19.955666 — immunology — Posted on 2020-02-28

257 Short and Long-read Sequencing Survey of the Dynamic Transcriptomes of African Swine Fever Virus and its Host

Olasz, F.; Tombacz, D.; Torma, G.; Csabai, Z.; Moldovan, N.; Dormo, A.; Prazsak, I.; Meszaros, I.; Magyar, T.; Tamas, V.; Zadori, Z.; Boldogkoi, Z.

10.1101/2020.02.27.967695 — genomics — Posted on 2020-02-28

258 Trans-generational effect of protein restricted diet on adult body and wing size of Drosophila melanogaster

Yadav, P.; Krittika, S.

10.1101/2020.02.17.952101 — evolutionary biology — Posted on 2020-02-28

Vila, J. C. C.; Liu, Y.-Y.; Sanchez, A.

10.1101/2020.02.26.966473 — ecology — Posted on 2020-02-28

260 Multiple roles for the ESCRT machinery in maintaining plasma membrane homeostasis

Schmidt, O.; Weyer, Y.; Sprenger, S.; Widerin, M. A.; Eising, S.; Baumann, V.; Angelova, M.; Loewith, R.; Stefan, C. J.; Hess, M. W.; Froehlich, F.; Teis, D.

10.1101/2020.02.25.964452 — cell biology — Posted on 2020-02-28

261 Fluorophore-labelled RNA aptamers to common protein tags as super-resolution imaging reagents.

Wang, J.; Singh, A.; Ozer, A.; Zipfel, W. R.

10.1101/2020.02.27.968578 — biophysics — Posted on 2020-02-28

262 Voting-based integration algorithm improves causal network learning from interventional and observational data: an application to cell signaling network inference

Sinha, M.; Tadepalli, P.; Ramsey, S. A.

10.1101/2020.02.18.955153 — bioinformatics — Posted on 2020-02-28

263 Long-term in vivo Monitoring of Gliotic Sheathing of Ultrathin Entropic Coated Brain Microprobes with Fiber-based Optical Coherence Tomography

Dryg, I.; Xie, Y.; Bergmann, M.; Urban, G.; Shain, W.; Hofmann, U.

10.1101/2020.02.26.966887 — bioengineering — Posted on 2020-02-28

264 An original structural fold underlies the multitask P1, a silencing suppressor encoded by the Rice yellow mottle virus

Poignavent, V.; Hoh, F.; Terral, G.; Yang, Y.; Gillet, F.-x.; Kim, J. H.; Allemand, F.; Lacombe, E.; Brugidou, C.; Cianferani, S.; Demene, H.; Vignols, F.

10.1101/2020.02.24.963488 — pathology — Posted on 2020-02-27

265 A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

Okaty, B. W.; Sturrock, N.; Escobedo Lozoya, Y.; Chang, Y.; Lyon, K. A.; Alekseyenko, O. V.; Dymecki, S. M.

10.1101/2020.01.28.923375 — neuroscience — Posted on 2020-02-28

266 Motor cortical plasticity in response to skill acquisition in adult monkeys

Gupta, A.; Nashef, A.; Israely, S.; Segal, M.; Harel, R.; Prut, Y.

10.1101/2020.02.27.967562 — neuroscience — Posted on 2020-02-28

267 Adintoviruses: An Animal-Tropic Family of Midsize Eukaryotic Linear dsDNA (MELD) Viruses

Starrett, G. J.; Tisza, M. J.; Welch, N. L.; Belford, A.; Peretti, A.; Pastrana, D. V.; Buck, C. B.

10.1101/697771 — microbiology — Posted on 2020-02-27

268 Evolutionary epidemiology of Streptococcus iniae: linking mutation rate dynamics with adaptation to novel immunological landscapes

Silayeva, O.; Engelstaedter, J.; Barnes, A. C.

10.1101/355412 — microbiology — Posted on 2020-02-28

269 Numerical optimization of microfluidic vortex shedding for genome editing human primary T cells using machine learning

Jarrell, J. A.; Lievano, A. A.; Pan, F. L.; Lau, K. H. W. J.; Kirby, G. T. S.; Pawell, R. S.

10.1101/2020.02.26.960336 — immunology — Posted on 2020-02-27

270 B cells expressing authentic naive human VRC01-class BCRs can be primed and recruited to germinal centers in multiple independent mouse models

Huang, D.; Abbott, R. K.; Havenar-Daughton, C.; Skog, P.; Al-Kolla, R.; Groschel, B.; Blane, T.; Menis, S.; Tran, J. T.; Thinnes, T. C.; Volpi, S. A.; Pintea, M.; Voss, J. E.; Phelps, N.; Tingle, R.; Rodriguez, A. R.; Martin, G. S.; Kupryianov, S.; Schief, W. R.; Nemazee, D.; Crotty, S.

10.1101/2020.02.24.963629 — immunology — Posted on 2020-02-28

271 Frequency-specific suppression of locomotor components by the white+ gene in Drosophila melanogaster adult flies

Xiao, C.; Qiu, S.

10.1101/2020.02.26.966937 — genetics — Posted on 2020-02-28

272 Unveiling Crucivirus Diversity by Mining Metagenomic Data

de la Higuera, I.; Kasun, G. W.; Torrance, E. L.; Pratt, A. A.; Maluenda, A.; Colombet, J.; Bisseux, M.; Ravet, V.; Dayaram, A.; Stainton, D.; Kraberger, S.; Zawar-Reza, P.; Goldstien, S.; Briskie, J. V.; White, R.; Taylor, H.; Gomez, C.; Ainley, D. G.; Harding, J. S.; Fontenele, R. S.; Schreck, J.; Ribeiro, S. G.; Oswald, S. A.; Arnold, J.; Enault, F.; Varsani, A.; Stedman, K. M.

10.1101/2020.02.27.967703 — evolutionary biology — Posted on 2020-02-27

273 Phylogenetic and ontogenetic changes of the anatomical organization and modularity in the skull of archosaurs.

Lee, H. W.; Esteve-Altava, B.; Abzhanov, A.

10.1101/2020.02.21.960435 — evolutionary biology — Posted on 2020-02-27

274 Crosstalk between invadopodia and the extracellular matrix

Iizuka, S.; Leon, R. P.; Gribbin, K. P.; Zhang, Y.; Navarro, J.; Smith, R.; Devlin, K.; Wang, L. G.; Gibbs, S. L.; Korkola, J.; Nan, X.; Courtneidge, S. A.

10.1101/2020.02.26.966762 — cancer biology — Posted on 2020-02-27

275 Leveraging Heterogeneous Network Embedding for Metabolic Pathway Prediction

M. A. Basher, A.; Hallam, S.

10.1101/2020.02.20.940205 — bioinformatics — Posted on 2020-02-27

276 Characterizing Trabecular Bone Properties near the Glenohumeral Joint Following Brachial Plexus Birth Injury

Fawcett, E. B.; McCormick, C. M.; Murray, A. F.; Crouch, D. L.; Saul, K. R.; Cole, J. H.

10.1101/2020.02.26.967224 — bioengineering — Posted on 2020-02-27

277 Multi-Approach and Multi-Scale Model of CD4+ T Cells Predicts Switch-Like and Oscillatory Emergent Behaviors in Inflammatory Response to Infection

Wertheim, K.; Puniya, B. L.; Fleur, A. L.; Shah, A. R.; Barberis, M.; Helikar, T.

10.1101/2020.02.26.964502 — systems biology — Posted on 2020-02-27

278 Supervising the PhD: identifying common mismatches in expectations between candidate and supervisor to improve research training outcomes

Cardilini, A. P.; Risely, A.; Richardson, M. F.

10.1101/2020.02.20.958520 — scientific communication and education — Posted on 2020-02-27

279 Perturbation of GABA Biosynthesis Links Cell Cycle to Control Arabidopsis thaliana Leaf Development

Gong, Y.; Yue, H.; Xiang, Y.; Yu, G.

10.1101/2020.02.21.960393 — plant biology — Posted on 2020-02-27

280 Rapid evolution in managed grasslands: different land-use regimes are associated with contrasting phenotypes in Plantago lanceolata

Gaspar, B.; Durka, W.; Bossdorf, O.

10.1101/2020.02.27.967448 — plant biology — Posted on 2020-02-27

281 The Transition from Acute to Chronic Pain: Dynamic Epigenetic Reprogramming of the Mouse Prefrontal Cortex up to One Year Following Nerve Injury

Topham, L.; Gregoire, S.; Kang, H.; Salmon-Divon, M.; Lax, E.; Millecamps, M.; Szyf, M.; Stone, L.

10.1101/2020.02.22.956128 — neuroscience — Posted on 2020-02-27

282 Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube

Symonds, A. C.; Buckley, C. E.; Williams, C. A.; Clarke, J. D.

10.1101/2020.02.16.950543 — neuroscience — Posted on 2020-02-27

283 Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex

Eichmueller, O. L.; Corsini, N. S.; Vertesy, A.; Scholl, T.; Gruber, V.-E.; Peer, A. M.; Chu, J.; Novatchkova, M.; Paredes, M. F.; Feucht, M.; Knoblich, J. A.

10.1101/2020.02.27.967802 — neuroscience — Posted on 2020-02-27

284 Glucose-mediated expansion of a gut commensal bacterium promotes Plasmodium infection through alkalizing mosquito midgut

Wang, M.; An, Y.; Dong, S.; Feng, Y.; Gao, L.; Wang, P.; Dimopoulus, G.; Tang, H.; Wang, J.

10.1101/2020.02.27.967315 — microbiology — Posted on 2020-02-27

285 Antarctic cryptoendolithic bacterial lineages of pre-Cambrian origin as proxy for Mars colonization

Albanese, D.; Coleine, C.; Rota-Stabelli, O.; Onofri, S.; Tringe, S.; Stajich, J. E.; Selbmann, L.; Donati, C.

10.1101/2020.02.27.967604 — microbiology — Posted on 2020-02-27

286 Identification of viruses from fungal transcriptomes

Jo, Y.; Choi, H.; Chu, H.; Cho, W. K.

10.1101/2020.02.26.966903 — microbiology — Posted on 2020-02-27

287 Biofilms deform soft surfaces and disrupt epithelia.

Cont, A.; Rossy, T.; Al-Mayyah, Z.; Persat, A.

10.1101/2020.01.29.923060 — microbiology — Posted on 2020-02-27

288 Epitope-based peptide vaccines predicted against novel coronavirus disease caused by SARS-CoV-2

Li, L.; Sun, T.; He, Y.; Li, W.; Fan, Y.; Zhang, J.

10.1101/2020.02.25.965434 — immunology — Posted on 2020-02-27

289 Integrating multiple experimental data to determine conformational ensembles of an intrinsically disordered protein

Gomes, G.-N. W.; Krzeminski, M.; Martin, E.; Mittag, T.; Head-Gordon, T.; Forman-Kay, J.; Gradinaru, C.

10.1101/2020.02.05.935890 — biophysics — Posted on 2020-02-27

290 Quality control and processing of nascent RNA profiling data

Smith, J. P.; Dutta, A.; Sathyan, K. M.; Guertin, M. J.; Sheffield, N. C.

10.1101/2020.02.27.956110 — bioinformatics — Posted on 2020-02-27

291 In silico chemical profiling and identification of neuromodulators from Curcuma amada targeting Acetylcholinesterase

Ali, M. C.; Munni, Y. A.; Das, R.; Sultana, M.; Akter, N.; Rahman, M.; Uddin, M. N.; Das, K.; Hossen, M.; Hannan, M. A.; Dash, R.

10.1101/2020.02.22.960732 — bioinformatics — Posted on 2020-02-27

292 AnnotatorJ: an ImageJ plugin to ease hand-annotation of cellular compartments

Hollandi, R.; Horvath, P.

10.1101/2020.02.27.968362 — bioinformatics — Posted on 2020-02-27

293 Instrumented immobilizing boot quantifies reduced Achilles tendon loading during gait

Hullfish, T. J.; O'Connor, K. M.; Baxter, J. R.

10.1101/2020.02.27.968495 — bioengineering — Posted on 2020-02-27

294 Automated detection of glaucoma with interpretable machine learning using clinical data and multi-modal retinal images

Mehta, P.; Petersen, C.; Wen, J. C.; Banitt, M. R.; Chen, P. P.; Bojikian, K. D.; Egan, C.; Lee, S.-I.; Balazinska, M.; Lee, A. Y.; Rokem, A.; The UK Biobank Eye and Vision Consortium,

10.1101/2020.02.26.967208 — bioengineering — Posted on 2020-02-27

295 Evaluation of the functional role of the maize Glossy2 and Glossy2-like genes in cuticular lipid deposition

Alexander, L. E.; Okazaki, Y.; Schelling, M. A.; Davis, A.; Zheng, X.; Rizhsky, L.; Yandeau-Nelson, M.; Saito, K.; Nikolau, B. J.

10.1101/2020.02.27.968321 — biochemistry — Posted on 2020-02-27

296 Latent learning drives sleep-dependent plasticity in distinct CA1 subpopulations

Guo, W.; Zhang, J. J.; Newman, J.; Wilson, M. A.

10.1101/2020.02.27.967794 — neuroscience — Posted on 2020-02-27

297 Bottom-up control of leakage in spectral electrophysiological source imaging via structured sparse bayesian learning

Gonzalez-Moreira, E.; Paz-Linares, D.; Areces-Gonzalez, A.; Wang, Y.; Li, M.; Harmony, T.; Valdes-Sosa, P. A.

10.1101/2020.02.25.964684 — neuroscience — Posted on 2020-02-27

298 Metastable attractors explain the variable timing of stable behavioral action sequences

Recanatesi, S.; Pereira Obilinovic, U.; Murakami, M.; Mainen, Z.; Mazzucato, L.

10.1101/2020.01.24.919217 — neuroscience — Posted on 2020-02-27

299 Investigating the neuronal oscillatory correlates of the Gratton effect

van Es, M. W. J.; Gross, J.; Schoffelen, J.-M.

10.1101/2020.02.27.967463 — neuroscience — Posted on 2020-02-27

300 CRISPR Screen in Regulatory T Cells Reveals Ubiquitination Modulators of Foxp3

Cortez, J. T.; Montauti, E.; Shifrut, E.; Zhang, Y.; Shaked, O.; Xu, Y.; Roth, T.; Simeonov, D.; Zhang, Y.; Chen, S.; Li, Z.; Vogel, I. A.; Prator, G. Y.; Zhang, B.; Lee, Y.; Sun, Z.; Ifergan, I.; Van Gool, F.; Bluestone, J. A.; Marson, A.; Fang, D.

10.1101/2020.02.26.966911 — immunology — Posted on 2020-02-27

301 miR-142 regulates IL-6 signalling during host immune response to Staphylococcus epidermidis infection in zebrafish

Dhanagovind, P.; Kujur, P. K.; Swain, R. K.; Banerjee, S.

10.1101/2020.02.26.960443 — immunology — Posted on 2020-02-27

302 In silico design of Phl p 6 variants with altered folding stability significantly impacts antigen processing, immunogenicity and immune polarization

Winter, P.; Stubenvoll, S.; Scheiblhofer, S.; Joubert, I. A.; Strasser, L.; Briganser, C.; Soh, W. T.; Hofer, F.; Kamenik, A. S.; Dietrich, V.; Michelini, S.; Laimer, J.; Lackner, P.; Horejs-Hoeck, J.; Tollinger, M.; Liedl, K. R.; Brandstetter, J.; Huber, C. G.; Weiss, R.

10.1101/2020.02.26.967265 — immunology — Posted on 2020-02-27

303 A genome-wide CRISPR screen reveals a role for the BRD9-containing non-canonical BAF complex in regulatory T cells

Loo, C.-S.; Gatchalian, J.; Liang, Y.; Leblanc, M.; Xie, M.; Ho, J.; Venkatraghavan, B.; Hargreaves, D. C.; Zheng, Y.

10.1101/2020.02.26.964981 — immunology — Posted on 2020-02-27

304 Latent Plasticity of Effector-like Exhausted CD8 T cells contributes to memory responses

Raju, S.; Xia, Y.; Daniel, B.; Yost, K. E.; Bradshaw, E.; Tonc, E.; Verbaro, D. J.; Satpathy, A. T.; Egawa, T.

10.1101/2020.02.22.960278 — immunology — Posted on 2020-02-27

305 Languages, evolution and statistics: human sound systems were shaped by changes in bite configuration. Response to Tarasov & Uyeda (2020)

Blasi, D. E.; Moran, S.; Moisik, S.; Widmer, P.; Dediu, D.; Bickel, B.

10.1101/2020.02.27.965400 — evolutionary biology — Posted on 2020-02-27

306 New tools for diet analyses: nanopore sequencing of metagenomic DNA from rat stomach contents to quantify diet

Pearman, W.; Smith, A. N. H.; Breckell, G.; Dale, J.; Freed, N. E.; Silander, O. K.

10.1101/363622 — ecology — Posted on 2020-02-27

307 Integration of Mechanistic Immunological Knowledge into a Machine Learning Pipeline Increases Predictive Power

Culos, A. E.; Tsai, A. S.; Stanley, N.; Becker, M.; Ghaemi, M. S.; McIlwain, D. R.; Tanada, A.; Fallahzadeh, R.; Nassar, H.; Ganio, E.; Peterson, L.; Han, x.; Stelzer, I.; Ando, K.; Gaudilliere, D.; Phongpreecha, T.; Maric, I.; Chang, A. L.; Shaw, G. M.; Stevenson, D. K.; Bendall, S.; Davis, K.; Fantl, W. C.; Nolan, G. P.; Hastie, T.; Tibshirani, R. j.; Angst, M.; Gaudilliere, B.; Aghaeepour, N.

10.1101/2020.02.26.967232 — bioinformatics — Posted on 2020-02-27

308 Bile acid supplementation improves murine pancreatitis in association with the gut microbiota

Wan, Y.-D.; Zhu, R.-X.; Pan, X.-T.

10.1101/2020.02.13.948547 — bioinformatics — Posted on 2020-02-27

309 Novel Electrodes for Reliable EEG Recordings on Coarse and Curly Hair

Etienne, A.; Laroia, T.; Weigle, H.; Afelin, A.; Kelly, S. K.; Krishnan, A.; Grover, P.

10.1101/2020.02.26.965202 — bioengineering — Posted on 2020-02-27

310 Forelimb unloading impairs glenohumeral muscle development in growing rats

Tushak, S. K.; Tamburro, M. K.; Fawcett, E. B.; Merritt, L. E.; Saul, K. R.; Cole, J. H.

10.1101/2020.02.26.967273 — bioengineering — Posted on 2020-02-27

311 mTOR-driven widespread exon skipping renders multifaceted gene regulation and proteome complexity

Cheng, S.; Fahmi, N. A.; Park, M.; Chang, J.-W.; Sun, J.; Thao, K.; Yeh, H.-S.; Zhang, W.; Yong, J.

10.1101/2020.02.27.967737 — biochemistry — Posted on 2020-02-27

312 Rtrack: a software package for reproducible automated water maze analysis

Overall, R. W.; Zocher, S.; Garthe, A.; Kempermann, G.

10.1101/2020.02.27.967372 — animal behavior and cognition — Posted on 2020-02-27

313 Effect of choline-phosphate cytidylyltransferase gene (pcyt-1) expression on departure of pine wood nematode, Bursaphelenchus xylophilus (Nematoda: Aphelenchoididae), from Monochamus alternatus (Coleoptera:Cerambycidae)

Wang, Y.; Chen, F.

10.1101/2020.02.22.943852 — zoology — Posted on 2020-02-27

314 High school Internship Program in Integrated Mathematical Oncology (HIP IMO) - five-year experience at Moffitt Cancer Center

Enderling, H.; Altrock, P. M.; Andor, N.; Basanta, D.; Brown, J. S.; Gatenby, R.; Marusyk, A.; Rejniak, K. A.; Silva, A.; Anderson, A. R.

10.1101/2020.02.27.967950 — scientific communication and education — Posted on 2020-02-27

315 Hook Shape of Growing Leaves Results from an Active Regulation

Riviere, M.; Corre, Y.; Peaucelle, A.; Derr, J.; Douady, S.

10.1101/2020.02.27.967513 — plant biology — Posted on 2020-02-27

316 FreiPose: A Deep Learning Framework for Precise Animal Motion Capture in 3D Spaces

Zimmermann, C.; Schneider, A.; Alyahyay, M.; Brox, T. S.; Diester, I.

10.1101/2020.02.27.967620 — neuroscience — Posted on 2020-02-27

317 ULK1 and ULK2 are less redundant than previously thought: Computational analysis uncovers distinct regulation and functions of these autophagy induction proteins

Demeter, A.; Romero-Mulero, M. C.; Csabai, L.; Olbei, M.; Sudhakar, P.; Haerty, W.; Korcsmaros, T.

10.1101/2020.02.27.967901 — molecular biology — Posted on 2020-02-27

318 Necrosignaling: Cell death triggers antibiotic survival pathways in bacterial swarms

Bhattacharyya, S.; Walker, D. M.; Harshey, R. M.

10.1101/2020.02.26.966986 — microbiology — Posted on 2020-02-27

319 Cell-to-cell and genome-to-genome variability of Adenovirus transcription tuned by the cell cycle

Suomalainen, M.; Prasad, V.; Kannan, A.; Greber, U. F.

10.1101/2020.02.27.967471 — microbiology — Posted on 2020-02-27

320 SkewIT: Skew Index Test for detecting mis-assembled bacterial genomes

Lu, J.; Salzberg, S.

10.1101/2020.02.27.968214 — genomics — Posted on 2020-02-27

321 CandiHap: a toolkit for haplotype analysis for sequence of samples and fast identification of candidate causal gene(s) in genome-wide association study

Li, X.; Shi, Z.; Qie, Q.; Gao, J.; Wang, X.; Han, Y.

10.1101/2020.02.27.967539 — bioinformatics — Posted on 2020-02-27

322 A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution

Paudel, B. P.; Moye, A. L.; Abou Assi, H.; El-Khoury, R.; Cohen, S. B.; Birrento, M. L.; Samosorn, S.; Intharapichai, K.; Tomlinson, C. G.; Teulade-Fichou, M.-P.; Gonzalez, C.; Beck, J. L.; Damha, M. J.; van Oijen, A. M.; Bryan, T. M.

10.1101/2020.02.26.965269 — biochemistry — Posted on 2020-02-27

323 Gradient of Tactile Properties in the Rat Whisker Pad

Azouz, R.; Gugig, E.; Sharma, H.

10.1101/2020.02.27.967778 — neuroscience — Posted on 2020-02-27

324 ICOS enhances follicular T helper responses and deteriorates the pathogenic process of liver in mice infected with Schistosoma japonicum

Wang, B.; Liang, S.; Wang, Y.-Y.; Wang, Y.; Xia, C.-M.

10.1101/2020.02.27.968248 — immunology — Posted on 2020-02-27

325 LC-Based Metabolomics and Multivariate Analyses Reveal Metabolite Variations in Different Propagation Methods of Eurycoma longifolia Roots Harvested at Different Ages and Locations

Alias, N. N.; Azizan, K. A.; Basherudin, N.; Hassan, N. H.; Abdullah, N.

10.1101/2020.02.27.967786 — systems biology — Posted on 2020-02-27

326 The ACE2 expression of maternal-fetal interface and fetal organs indicates potential risk of vertical transmission of SARS-COV-2

Li, M.; Chen, L.; Xiong, C.; Li, X.

10.1101/2020.02.27.967760 — genomics — Posted on 2020-02-27

327 A systematic, label-free method for identifying RNA-associated proteins in vivo provides insights into vertebrate ciliary beating

Drew, K.; Lee, C.; Cox, R. M.; Dang, V.; Devitt, C. C.; Papoulas, O.; Huizar, R. L.; Marcotte, E. M.; Wallingford, J. B.

10.1101/2020.02.26.966754 — developmental biology — Posted on 2020-02-27

328 Immunotherapy efficacy in colorectal cancer is dependent on activation of a microbial-metabolite-immune circuit

Mager, L.; Burkhard, R.; Cooke, N.; Brown, K.; Ramay, H.; Paik, S.; Stagg, J.; Grooves, R.; Gallo, M.; Lewis, I.; Geuking, M.; McCoy, K.

10.1101/2020.02.26.965533 — cancer biology — Posted on 2020-02-27

329 Secreted autotaxin through LPA suppresses chemotaxis and tumor infiltration of CD8+ T Cells

Matas-Rico, E.; van der Haar Avila, I.; van Zon, M.; Morris, A. J.; Koster, J.; Salgado-Polo, F.; de Kivit, S.; de Rink, I.; Lanca, T.; Alba, J. M.; Johnson, Z.; Farrow, S.; Haanen, J.; Schumacher, T. N.; Perrakis, A.; Borst, J.; Verbrugge, I.; van den Berg, J.; Moolenaar, W. H.

10.1101/2020.02.26.966291 — cancer biology — Posted on 2020-02-27

330 Drug GRADE: an integrated analysis of population growth and cell death reveals drug- specific and cancer subtype-specific response profiles

Schwartz, H. R.; Richards, R.; Fontana, R. E.; Joyce, A. J.; Honeywell, M. E.; Lee, M. J.

10.1101/2020.02.26.966689 — systems biology — Posted on 2020-02-27

331 Comparative analysis of primer-probe sets for the laboratory confirmation of SARS-CoV-2

Jung, Y. J.; Park, G.-S.; Moon, J. H.; Ku, K.; Beak, S.-H.; Kim, S.; Park, E. C.; Park, D.; Lee, J.-H.; Byeon, C. W.; Lee, J. J.; Maeng, J.-s.; Kim, S. J.; Kim, S. I.; Kim, B.-T.; Lee, M. J.; Kim, H. G.

10.1101/2020.02.25.964775 — microbiology — Posted on 2020-02-27

332 Epitope-based peptide vaccines predicted against novel coronavirus disease caused by SARS-CoV-2

Li, L.; Sun, T.; He, Y.; Li, W.; Fan, Y.; Zhang, J.

10.1101/2020.02.25.965434 — immunology — Posted on 2020-02-27

333 A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism.

Buckley, R. M.; Davis, B. W.; Brashear, W. A.; Farias, F. H. G.; Kuroki, K.; Graves, T.; Hillier, L. W.; Kremitzki, M.; Li, G.; Middleton, R.; Minx, P. M.; Tomlinson, C.; Lyons, L. A.; Murphy, W. J.; Warren, W. C.

10.1101/2020.01.06.896258 — genomics — Posted on 2020-02-27

334 Arabidopsis LTR retrotransposons and their regulation by epigenetically activated small RNA

Lee, S. C.; Ernst, E.; Berube, B.; Borges, F.; Parent, J.-S.; Ledon, P.; Schorn, A.; Martienssen, R. A.

10.1101/2020.01.24.919167 — genomics — Posted on 2020-02-27

335 Structure-based drug design, virtual screening and high-throughput screening rapidly identify antiviral leads targeting COVID-19

Jin, Z.; Du, X.; Xu, Y.; Deng, Y.; Liu, M.; Zhao, Y.; Zhang, B.; Li, X.; Zhang, L.; Duan, Y.; Yu, J.; Wang, L.; Yang, K.; Liu, F.; You, T.; Liu, X.; Yang, X.; Bai, F.; Liu, H.; Liu, X.; Guddat, L. W.; Xiao, G.; Qin, C.; Shi, Z.; Jiang, H.; Rao, Z.; Yang, H.

10.1101/2020.02.26.964882 — biochemistry — Posted on 2020-02-27

336 In Vitro Assessment of Antioxidant activity, Antimicrobial, and cytotoxicity of ultrasound-assisted acetone extracts of Plectranthus amboinicus

Ye, X.

10.1101/2020.02.07.938928 — pharmacology and toxicology — Posted on 2020-02-27

337 In vivo repair of a protein underlying a neurological disorder by programmable RNA editing

Sinnamon, J.; Kim, S. Y.; Fisk, J. R.; Song, Z.; Nakai, H.; Jeng, S.; McWeeney, S. K.; Mandel, G.

10.1101/2020.02.26.966820 — neuroscience — Posted on 2020-02-27

338 RADX Sustains POT1 Function at Telomeres to Counteract RAD51 Binding, which Triggers Telomere Fragility

Lingner, J.; Glousker, G.; Briod, A.-S.

10.1101/2020.01.20.912634 — molecular biology — Posted on 2020-02-27

339 Whole genome comparisons of Staphylococcus agnetis isolates from cattle and chickens

Shwani, A.; Adkins, P. R. F.; Ekesi, N. S.; Alrubaye, A. A.; Calcutt, M. J.; Middleton, J. R.; Rhoads, D. D.

10.1101/2020.01.06.896779 — microbiology — Posted on 2020-02-27

340 Identification of Photorhabdus symbionts by MALDI-TOF mass spectrometry

Hill, V.; Kuhnert, P.; Erb, M.; Machado, R. A. R.

10.1101/2020.01.10.901900 — microbiology — Posted on 2020-02-27

341 Increasing Host Cellular Receptor--Angiotensin-Converting Enzyme 2 (ACE2) Expression by Coronavirus may Facilitate 2019-nCoV Infection

Wang, P.-H.

10.1101/2020.02.24.963348 — microbiology — Posted on 2020-02-27

342 An Effective CTL Peptide Vaccine for Ebola Zaire Based on Survivors' CD8+ Targeting of a Particular Nucleocapsid Protein Epitope with Potential Implications for COVID-19 Vaccine Design

Herst, C. V.; Burkholz, S.; Sidney, J.; Sette, A.; Harris, P. E.; Massey, S.; Brazel, T.; Cunha-Neto, E.; Rosa, D. S.; Chao, W. C. H.; Carback, R. T.; Hodge, T.; Wang, L.; Ciotlos, S.; Lloyd, P.; Rubsamen, R. M.

10.1101/2020.02.25.963546 — immunology — Posted on 2020-02-27

343 The Geometry and Genetics of Hybridization

Schneemann, H.; De Sanctis, B.; Roze, D.; Bierne, N.; Welch, J. J.

10.1101/862235 — evolutionary biology — Posted on 2020-02-27

344 Phylogeographic and phylodynamic approaches to epidemiological hypothesis testing

Dellicour, S.; Lequime, S.; Vrancken, B.; Gill, M. S.; Bastide, P.; Gangavarapu, K.; Matteson, N. L.; Tan, Y.; du Plessis, L.; Fisher, A. A.; Nelson, M. I.; Gilbert, M.; Suchard, M. A.; Andersen, K. G.; Grubaugh, N. D.; Pybus, O. G.; Lemey, P.

10.1101/788059 — evolutionary biology — Posted on 2020-02-27

345 Apical Constriction Reversal upon Mitotic Entry Underlies Different Morphogenetic Outcomes of Cell Division

Ko, C. S.; Kalakuntla, P.; Martin, A. C.

10.1101/862821 — developmental biology — Posted on 2020-02-27

346 Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation

Zeeshan, M.; Pandey, R.; Ferguson, D. J. P.; Tromer, E. C.; Markus, R.; Abel, S.; Brady, D.; Daniel, E.; Stanway, R. R.; Bottrill, A. R.; Le Roch, K. G.; Holder, A. A.; Waller, R. F.; Guttery, D. S.; Tewari, R.

10.1101/767830 — cell biology — Posted on 2020-02-27

347 The synergistic actions of hydrolytic genes in coexpression networks reveal the potential of Trichoderma harzianum for cellulose degradation

Almeida, D. A.; Horta, M. A. C.; Ferreira Filho, J. A.; Murad, N. F.; de Souza, A. P.

10.1101/2020.01.14.906529 — bioinformatics — Posted on 2020-02-27

348 Increasing proteome coverage using cysteine-specific DIA Mass spectrometry - Cys-DIA

Tahir, M.; Nawrocki, A.; Ditzel, H. J.; Larsen, M. R.

10.1101/2020.02.27.966861 — biochemistry — Posted on 2020-02-27

349 Iterative Refinement of Cellular Identity from Single-Cell Data Using Online Learning

Gao, C.; Preissl, S.; Luo, C.; Castanon, R.; Sandoval, J.; Rivkin, A.; Nery, J.; Behrens, M. M.; Ecker, J. R.; Ren, B.; Welch, J. D.

10.1101/2020.01.16.909861 — bioinformatics — Posted on 2020-02-27

350 SEQing: web-based visualization of iCLIP and RNA-seq data in an interactive python framework

Lewinski, M.; Bramkamp, Y.; Köster, T.; Staiger, D.

10.1101/2019.12.17.865873 — bioinformatics — Posted on 2020-02-27

351 The Derived-Band Envelope Following Response and its Sensitivity to Sensorineural Hearing Deficits

Keshishzadeh, S.; Garrett, M.; Vasilkov, V.; Verhulst, S.

10.1101/820704 — bioengineering — Posted on 2020-02-27

352 Intact RNA structurome reveals mRNA structure-mediated regulation of miRNA cleavage in vivo

Yang, M.; Woolfenden, H. C.; Zhang, Y.; Fang, X.; Liu, Q.; Vigh, M. L.; Cheema, J.; Yang, X.; Norris, M.; Yu, S.; Carbonell, A.; Brodersen, P.; Wang, J.; Ding, Y.

10.1101/2019.12.21.885699 — molecular biology — Posted on 2020-02-27

353 Dielectrophoresis assisted rapid, selective and single cell detection of antibiotic resistant bacteria with G-FETs

Kumar, N.; Wang, W.; Ortiz-Marquez, J. C.; Catalano, M.; Gray, M.; Biglari, N.; Hikari, K.; Ling, X.; Gao, J.; van Opijnen, T.; Burch, K. S.

10.1101/842187 — microbiology — Posted on 2020-02-27

354 Resetting proteostasis with ISRIB prevents pulmonary fibrosis

Watanabe, S.; Markov, N. S.; Lu, Z.; Piseaux Aillon, R.; Soberanes, S.; Runyan, C. E.; Ren, Z.; Grant, R. A.; Maciel, M.; Abdala-Valencia, H.; Politanska, Y.; Nam, K.; Sichizya, L.; Kihshen, H. G.; Joshi, N.; McQuattie-Pimentel, A. C.; Morimoto, R. I.; Reyfman, P. A.; Budinger, G. S.; Misharin, A. V.

10.1101/2020.02.26.965566 — immunology — Posted on 2020-02-27

355 Phylogenomic approaches reveal how a climatic inversion and glacial refugia shape patterns of diversity in an African rain forest tree species

Helmstetter, A. J.; Amoussou, B. E. N.; Bethune, K.; Kandem, N. G.; Glele Kakai, R. L.; Sonke, B.; Couvreur, T. L. P.

10.1101/807727 — evolutionary biology — Posted on 2020-02-27

356 Social and non-social functions of infant vocalizations

Long, H.; Bowman, D.; Yoo, H.; Burkhardt-Reed, M.; Bene, E.; Oller, D. K.

10.1101/821371 — developmental biology — Posted on 2020-02-27

357 Continuum theory of active phase separation in cellular aggregates

Kuan, H.-S.; Pönisch, W.; Jülicher, F.; Zaburdaev, V.

10.1101/2020.02.26.966622 — biophysics — Posted on 2020-02-27

358 Beyond accessibility: ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

Bentsen, M.; Goymann, P.; Schultheis, H.; Klee, K.; Petrova, A.; Wiegandt, R.; Fust, A.; Preussner, J.; Kuenne, C.; Braun, T.; Kim, J.; Looso, M.

10.1101/869560 — bioinformatics — Posted on 2020-02-27

359 Interaction of contexts in context-dependent orientation estimation

Dekel, R.; Sagi, D.

10.1101/816355 — neuroscience — Posted on 2020-02-27

360 Methods matter: your measures of explicit and implicit processes in visuomotor adaptation affect your results

Maresch, J.; Werner, S.; Donchin, O.

10.1101/702290 — neuroscience — Posted on 2020-02-27

361 Transcription factor motifs in anterior insula gene-expression are altered in mood disorder brains

Arasappan, D.; Eickhoff, S. B.; Nemeroff, C. B.; Hofmann, H.; Jabbi, M.

10.1101/864900 — neuroscience — Posted on 2020-02-27

362 Dopamine transporter trafficking and Rit2 GTPase: In vivo impact and mechanism of action

Fagan, R. R.; Kearney, P. J.; Sweeney, C. G.; Luethi, D.; Schoot Uiterkamp, F. E.; Schicker, K.; O'Connor, L. C.; Sitte, H. H.; Melikian, H. E.

10.1101/712448 — neuroscience — Posted on 2020-02-27

363 The assembly of Hfq into foci-like structures in response to long-term nitrogen starvation in Escherichia coli

McQuail, J.; Switzer, A.; Burchell, L.; Wigneshweraraj, R.

10.1101/2020.01.10.901611 — microbiology — Posted on 2020-02-27

364 Identification of the first oomycete mating-type locus sequence in the grapevine downy mildew pathogen, Plasmopara viticola

Dussert, Y.; Legrand, L.; Mazet, I. D.; Couture, C.; Piron, M.-C.; Serre, R.-F.; Bouchez, O.; Mestre, P.; Toffolatti, S. L.; Giraud, T.; Delmotte, F.

10.1101/2020.02.26.962936 — evolutionary biology — Posted on 2020-02-27

365 The diversity and distribution of endophytes across biomes, plant phylogeny, and host tissues--how far have we come and where do we go from here?

Harrison, J. G.; Griffin, E. A.

10.1101/793471 — ecology — Posted on 2020-02-27

366 Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity.

Quillien, A.; Boulet, M.; Ethuin, S.; Vandel, L.

10.1101/2020.02.27.967810 — developmental biology — Posted on 2020-02-27

367 Drosha Regulates Oogenesis and microRNAs Germline Autonomously and Non autonomously in C. elegans

Minogue, A. L.; Trimmer, K. A.; Seeman, J. H.; Kalia, A.; Arur, S.

10.1101/2020.02.26.966648 — developmental biology — Posted on 2020-02-27

368 Plasmodesmata-like intercellular connections by plant remorin in animal cells

Wei, Z.; Tan, S.; Liu, T.; Wu, Y.; Lei, J.-G.; Chen, Z.; Friml, J.; Xue, H.-W.; Liao, K.

10.1101/791137 — cell biology — Posted on 2020-02-27

369 How to Pare a Pair: Topology Control and Pruning in Intertwined Complex Networks.

Kramer, F.; Modes, C. D.

10.1101/763649 — biophysics — Posted on 2020-02-27

370 Kinetic fingerprints differentiate anti-Aβ therapies

Linse, S.; Scheidt, T.; Bernfur, K.; Vendruscolo, M.; Dobson, C. M.; Cohen, S. I.; Sileikis, E.; Lundquist, M.; Qian, F.; O'Malley, T.; Bussiere, T.; Weinreb, P. H.; Xu, C. K.; Meisl, G.; Devenish, S.; Knowles, T. P.; Hansson, O.

10.1101/815308 — biophysics — Posted on 2020-02-27

371 Energy landscape steering in SecYEG mediates dynamic coupling in ATP driven protein translocation

Crossley, J.; Fessl, T.; Watson, M. A.; Watkins, D.; Corey, R. A.; Allen, W. J.; Sabir, T.; Radford, S. E.; Collinson, I.; Tuma, R.

10.1101/793943 — biophysics — Posted on 2020-02-27

372 Alignment-Integrated Reconstruction of Ancestral Sequences Improves Accuracy

Aadland, K.; Kolaczkowski, B.

10.1101/2020.02.26.965186 — bioinformatics — Posted on 2020-02-27

373 Simultaneously vocalizing Asian barbets adopt different frequencies without coordinating temporal rhythms

Krishnan, A.

10.1101/754580 — animal behavior and cognition — Posted on 2020-02-27

374 Optimizing auditory brainstem response acquisition using interleaved frequencies

Buran, B. N.; Elkins, S.; Kempton, J. B.; Porsov, E. V.; Brigande, J. V.; David, S. V.

10.1101/781831 — neuroscience — Posted on 2020-02-27

375 Landmark-Based Navigation Instructions Improve Incidental Spatial Learning in Real-Life Environments

Wunderlich, A.; Gramann, K.

10.1101/789529 — neuroscience — Posted on 2020-02-27

376 LARP1 facilitates translational recovery after amino acid refeeding by preserving long poly(A)-tailed TOP mRNAs

Ogami, K.; Oishi, Y.; Nogimori, T.; Sakamoto, K.; Hoshino, S.-i.

10.1101/716217 — molecular biology — Posted on 2020-02-27

377 Recreation of an antigen-driven germinal center in vitro by providing B cells with phagocytic antigen

Alarcon, B.; Martinez-Riano, A.; Delgado, P.; Mendoza, P.; Oeste, C. L.; Abia, D.; Bovolenta, E. R.; Turner, M.

10.1101/2020.02.26.965921 — immunology — Posted on 2020-02-27

378 Myocardial damage induced by a single high dose of isoproterenol in C57Bl/6J mice triggers a persistent adaptive immune response against the heart.

Forte, E.; Panahi, M.; Ng, F. S.; Boyle, J.; Branca, J.; Bedard, O.; Hasham, M. G.; Benson, L.; Harding, S. E.; Rosenthal, N.; Sattler, S.

10.1101/2020.02.27.962696 — immunology — Posted on 2020-02-27

379 Sepsis-associated Pathways Segregate Cancer Groups

Tripathi, H.; Mukhopadhyay, S.; Mohapatra, S. K.

10.1101/635243 — genomics — Posted on 2020-02-27

380 Hidden genetic variance and residual allogamy contribute to increase the adaptive potential of selfing populations

Clo, J.; Ronfort, J.; Abu Awad, D.

10.1101/810515 — evolutionary biology — Posted on 2020-02-27

381 Social fluidity mobilizes contagion in human and animal populations

Colman, E.; Colizza, V.; Hanks, E. M.; Modlmeier, A. P.; Hughes, D. P.; Bansal, S.

10.1101/170266 — ecology — Posted on 2020-02-27

382 Emergent neutrality in consumer-resource dynamics

D'Andrea, R.; Gibbs, T.; O'Dwyer, J. P.

10.1101/710541 — ecology — Posted on 2020-02-27

383 Field-testing olfactory ability to understand human olfactory ecology

Hoover, K. C.; Botescu, D.; Fedurek, P.; Aarts, S.; Berbesque, J. C.

10.1101/270744 — ecology — Posted on 2020-02-27

384 Kin structure and roost fidelity in greater noctule bats

Santos, J. G. N. D.; Meyer, C.; Ibanez, C.; Popa-Lisseanu, A.; Juste, J.

10.1101/675215 — ecology — Posted on 2020-02-27

385 Adaptive Estimation for Epidemic Renewal and Phylogenetic Skyline Models

Parag, K. V.; Donnelly, C. A.

10.1101/703751 — ecology — Posted on 2020-02-27

386 CHD4-NURD controls spermatogonia survival and differentiation

de Castro, R. O.; Goitea, V.; Previato, L.; Carbajal, A.; Griffin, C.; Pezza, R.

10.1101/687137 — developmental biology — Posted on 2020-02-27

387 In silico stress fibre content affects peak strain in cytoplasm and nucleus but not in membrane for uniaxial substrate stretch

Abdalrahman, T.; Davies, N. H.; Franz, T.

10.1101/774976 — biophysics — Posted on 2020-02-27

388 In silico stress fibre content affects peak strain in cytoplasm and nucleus but not in membrane for uniaxial substrate stretch

Abdalrahman, T.; Davies, N. H.; Franz, T.

10.1101/774976 — biophysics — Posted on 2020-02-27

389 Multiplexable fluorescence lifetime imaging (FLIM) probes for Abl and Src-family kinases

Damayanti, N. P.; Jena, S.; Tan, J.; Irudayaraj, J. M. K.; Parker, L. L.

10.1101/655407 — biochemistry — Posted on 2020-02-27

390 Network analysis of workshop activities reveals increasing transdisciplinarity of German biodiversity research community

Geschke, J.; Lutz, M.; Vohland, K.

10.1101/2020.02.26.966432 — scientific communication and education — Posted on 2020-02-27

391 Low-protein/high-carbohydrate diet induces AMPK-dependent canonical and non-canonical thermogenic response in subcutaneous adipose tissue

Aquilano, K.; Sciarretta, F.; Turchi, R.; Li, B.-H.; Rosina, M.; Ceci, V.; Guidobaldi, G.; Arena, S.; D'Ambrosio, C.; Audano, M.; Salvatori, I.; Colella, B.; Faraonio, R.; Panebianco, C.; Pazienza, V.; Caruso, D.; Mitro, N.; Di Bartolomeo, S.; Scaloni, A.; Li, J.-Y.; Lettieri-Barbato, D.

10.1101/2020.02.26.966002 — physiology — Posted on 2020-02-27

392 Simulated trawling: Exhaustive swimming followed by extreme crowding as contributing reasons to variable fillet quality in trawl-caught Atlantic cod (Gadus morhua)

SVALHEIM, R. A.; Aas-Hansen, O.; Heia, K.; Karlsson-Drangsholt, A.; Olsen, S.-H.; Johnsen, H. K.

10.1101/372581 — physiology — Posted on 2020-02-27

393 Coordinated prefrontal state transition leads extinction of reward-seeking behaviors

Russo, E.; Ma, T.; Spanagel, R.; Durstewitz, D.; Toutounji, H.; Köhr, G.

10.1101/2020.02.26.964510 — neuroscience — Posted on 2020-02-27

394 Active Efficient Coding Explains the Development of Binocular Vision and its Failure in Amblyopia

Eckmann, S.; Klimmasch, L.; Shi, B. E.; Triesch, J.

10.1101/571802 — neuroscience — Posted on 2020-02-27

Mei, N.; Olafsson, E.; Rankine, S.; Soto, D.

10.1101/607069 — neuroscience — Posted on 2020-02-27

396 Evidence for modulation of EEG microstate sequence by vigilance level

Krylova, M.; Alizadeh, S.; Izyurov, I.; Teckentrup, V.; Chang, C.; van der Meer, J. N.; Erb, M.; Kroemer, N.; Koenig, T.; Walter, M.; Jamalabadi, H.

10.1101/2020.02.26.966150 — neuroscience — Posted on 2020-02-27

397 A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

Suzuki, K.; Elegheert, J.; Song, I.; Sasakura, H.; Senkov, O.; Kakegawa, W.; Clayton, A. J.; Chang, V. T.; Ferrer-Ferrer, M.; Miura, E.; Kaushik, R.; Ikeno, M.; Morioka, Y.; Takeuchi, Y.; Shimada, T.; Otsuka, S.; Stoyanov, S.; Watanabe, M.; Takeuchi, K.; Dityatev, A.; Aricescu, A. R.; Yuzaki, M.

10.1101/2020.02.27.967836 — neuroscience — Posted on 2020-02-27

398 Dynamic graph analysis reveals aging effects on motor network communication

Rosjat, N.; Wang, B. A.; Liu, L.; Fink, G. R.; Daun, S.

10.1101/2020.02.26.966325 — neuroscience — Posted on 2020-02-27

399 Natural selection influenced the genetic architecture of brain structure, behavioral and neuropsychiatric traits

Wendt, F. R.; Pathak, G. A.; Overstreet, C.; Tylee, D. S.; Gelernter, J.; Atkinson, E. G.; Polimanti, R.

10.1101/2020.02.26.966531 — evolutionary biology — Posted on 2020-02-27

400 Phylogenetic inference of changes in amino acid propensities with single-position resolution

Klink, G. V.; Kalinina, O. V.; Bazykin, G. A.

10.1101/589572 — evolutionary biology — Posted on 2020-02-27

401 Candida albicans genetic background influences mean and heterogeneity of drug responses and genome stability during evolution to fluconazole

Gerstein, A. C.; Berman, J.

10.1101/360347 — evolutionary biology — Posted on 2020-02-27

402 Caterpillars on a phytochemical landscape: the case of alfalfa and the Melissa blue butterfly

Forister, M. L.; Yoon, S.; Philbin, C. S.; Dodson, C. D.; Hart, B.; Harrison, J. G.; Shelef, O.; Fordyce, J. A.; Marion, Z. H.; Nice, C. C.; Richards, L. A.; Buerkle, C. A.; Gompert, Z.

10.1101/498139 — ecology — Posted on 2020-02-27

403 On the efficacy of restoration in stream networks: comments, critiques, and prospective recommendations

Murray-Stoker, D.

10.1101/611939 — ecology — Posted on 2020-02-27

404 Combinatorial action of transcription factors in open chromatin contributes to early cellular heterogeneity and organizer mesendoderm specification.

Bright, A. R.; Genesen, S. v.; Li, Q.; van Heeringen, S. J.; Grasso, A.; Veenstra, G. J. C.

10.1101/2020.02.26.966168 — developmental biology — Posted on 2020-02-27

405 Tissue mimetic hyaluronan bio-ink containing oriented collagen fibers to modulate hMSC spreading and differentiation

Schwab, A.; Helary, C.; Richards, G.; Alini, M.; Eglin, d. o.; D'Este, M.

10.1101/2020.02.26.966564 — bioengineering — Posted on 2020-02-27

406 The cue-reactivity paradigm: An ensemble of networks driving attention and cognition when viewing drug-related and natural-reward stimuli

Hill-Bowen, L. D.; Riedel, M. C.; Poudel, R.; Salo, T.; Flannery, J. S.; Camilleri, J. A.; Eickhoff, S. B.; Laird, A. R.; Sutherland, M. T.

10.1101/2020.02.26.966549 — neuroscience — Posted on 2020-02-27

407 Artesunate interacts with Vitamin D receptor to reverse mouse model of sepsis-induced immunosuppression via enhancing autophagy

Shang, S.; Wu, J.; Li, X.; Liu, X.; Li, P.; Zheng, C.; Wang, Y.; Liu, S.; Zheng, J.; Zhou, H.

10.1101/2020.02.26.966143 — pharmacology and toxicology — Posted on 2020-02-27

408 Oxytocin increases the pleasantness of affective touch and orbitofrontal cortex activity independent of valence

Chen, Y.; Becker, B.; Zhang, Y.; Cui, H.; Du, J.; Wernicke, J.; Kendrick, K.; Yao, S.

10.1101/2020.02.26.965830 — neuroscience — Posted on 2020-02-27

409 Intermittent hypoxia promotes functional neuroprotection from retinal ischemia in untreated first-generation offspring

Harman, J. C.; Guidry, J. J.; Gidday, J. M.

10.1101/2020.02.26.966457 — neuroscience — Posted on 2020-02-27

410 Deep neural networks identify context-specific determinants of transcription factor binding affinity

Zheng, A.; Lamkin, M.; Wu, C.; Su, H.; Gymrek, M.

10.1101/2020.02.26.965343 — genomics — Posted on 2020-02-27

411 Localized prediction of glutamate from whole-brain functional connectivity of the pregenual anterior cingulate cortex

Martens, L.; Kroemer, N. B.; Teckentrup, V.; Colic, L.; Palomero-Gallagher, N.; Li, M.; Walter, M.

10.1101/2020.02.26.966259 — neuroscience — Posted on 2020-02-27

412 KDM3A regulates alternative splicing of cell-cycle genes following DNA damage

Baker, M.; Petasny, M.; Bentata, M.; Kay, G.; Engal, E.; Nevo, Y.; Siam, A.; Dahan, S.; Salton, M.

10.1101/2020.02.26.965970 — molecular biology — Posted on 2020-02-27

413 Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations of mismatch repair genes in methotrexate-resistant HT-29 cells

Kim, A.; Shin, J.-Y.; Seo, J.-S.

10.1101/2020.02.26.965814 — genomics — Posted on 2020-02-27

414 Next-generation sequencing of pIJ101-based Streptomyces-E. coli shuttle vectors

Nybo, S. E.; Brown, K. V.

10.1101/2020.02.26.966358 — genetics — Posted on 2020-02-27

415 Clinical metagenomics bioinformatics pipeline for the identification of hospital-acquired pneumonia pathogens antibiotic resistance genes from bronchoalveolar lavage samples

Tournoud, M.; RUPPE, E.; Perrin, G.; Schicklin, S.; Guigon, G.; Mahe, P.; Lazarevic, V.; Hauser, S.; Mirande, C.; Levrat, A.; Louis, K.; Gervasi, G.; Schrenzel, J.

10.1101/2020.02.26.966309 — bioinformatics — Posted on 2020-02-27

416 Reducing monocarboxylate transporter MCT1 worsens experimental diabetic peripheral neuropathy

Jha, M. K.; Ament, X. H.; Yang, F.; Liu, Y.; Polydefkis, M.; Pellerin, L.; Morrison, B. M.

10.1101/2020.02.26.965152 — neuroscience — Posted on 2020-02-27

417 A plasmid locus associated with Klebsiella clinical infections encodes a microbiome-dependent gut fitness factor

Vornhagen, J.; Bassis, C.; Ramakrishnan, S.; Hein, R.; Mason, S.; Bergman, Y.; Sunshine, N.; Fan, Y.; Timp, W.; Schatz, M. C.; Young, V. B.; Simner, P. J.; Bachman, M. A.

10.1101/2020.02.26.963322 — microbiology — Posted on 2020-02-27

418 Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance

Huoh, Y.-S.; Wu, B.; Park, S.; Yang, D.; Bansal, K.; Greenwald, E.; Wong, W. P.; Mathis, D.; Hur, S.

10.1101/2020.02.26.966424 — immunology — Posted on 2020-02-27

419 Multiplexed conditional genome editing with Cas12a in Drosophila

Port, F.; Starostecka, M.; Boutros, M.

10.1101/2020.02.26.966333 — genetics — Posted on 2020-02-27

420 Adaptive potential and evolution in new environmental conditions

Koch, E. L.; Sbilordo, S. H.; Guillaume, F.

10.1101/2020.02.26.966119 — evolutionary biology — Posted on 2020-02-27

421 Phenotypic Noise and the Cost of Complexity

Rocabert, C.; Beslon, G.; Knibbe, C.; Bernard, S.

10.1101/2020.02.26.963843 — evolutionary biology — Posted on 2020-02-27

422 Multiplexed drug testing of tumor slices using a microfluidic platform

Horowitz, L. F.; Rodriguez, A. D.; Dereli-Korkut, Z.; Lin, R.; Castro, K.; Mikheev, A.; Monnat, R. J.; Folch, A.; Rostomily, R. C.

10.1101/2020.02.25.965137 — bioengineering — Posted on 2020-02-27

423 The Taste of Blood in Mosquitoes

Jove, V.; Gong, Z.; Hol, F. J.; Zhao, Z.; Sorrells, T. R.; Carroll, T. S.; Prakash, M.; McBride, C. S.; Vosshall, L. B.

10.1101/2020.02.27.954206 — neuroscience — Posted on 2020-02-27

424 Frequency of mispackaging of Prochlorococcus DNA by cyanophage

Laurenceau, R.; Raho, N.; Forget, M.; Arellano, A.; Chisholm, S. W.

10.1101/2020.02.18.953059 — microbiology — Posted on 2020-02-27

425 RNA-seq and scRNA-seq reveal trajectory progression of the retinal ganglion cell lineage in wild-type and Atoh7-null retinas

Wu, F.; Bard, J. E.; Kann, J.; Yergeau, D.; Sapkota, D.; Ge, Y.; Hu, Z.; Wang, J.; Liu, T.; Mu, X.

10.1101/2020.02.26.966093 — developmental biology — Posted on 2020-02-27

426 Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo.

Floc'hlay, S.; Molina Jimenez, M. D.; Hernandez, C.; Haillot, E.; Thomas-Chollier, M.; Lepage, T.; Thieffry, D.

10.1101/2020.02.26.966556 — developmental biology — Posted on 2020-02-27

427 60S subunit joining exposes nascent pre-40S rRNA for quality control

Rai, J.; Parker, M. D.; Huang, H.; Choi, S.; Ghalei, H.; Johnson, M. C.; Karbstein, K.; Stroupe, M. E.

10.1101/617910 — biochemistry — Posted on 2020-02-27

428 Chemical and structural investigation of the paroxetine-human serotonin transporter complex

Coleman, J. A.; Navratna, V.; Antermite, D.; Yang, D.; Bull, J. A.; Gouaux, E.

10.1101/2020.02.26.966895 — biochemistry — Posted on 2020-02-27

429 Developmental onset of enduring long-term potentiation in mouse hippocampus

Ostrovskaya, O. I.; Cao, G.; Eroglu, C.; Harris, K. M.

10.1101/787192 — neuroscience — Posted on 2020-02-27

430 Genomic profiling of circulating tumor DNA reveals genetics and residual disease in NK/T lymphoma

rao, J.; Zhang, W.; Li, Q.; Xiong, J.-K.; Li, J.-L.; Liu, J.; Chen, T.; Wen, Q.; Zeng, Y.-J.; Gao, L.; Gao, L.; Zhang, C.; Kong, P.-Y.; Liu, Y.; Zhang, X.

10.1101/800409 — genomics — Posted on 2020-02-27

431 PhenomeXcan: Mapping the genome to the phenome through the transcriptome

Pividori, M.; Rajagopal, P. S.; Barbeira, A. N.; Liang, Y.; Melia, O.; Bastarache, L.; Park, Y.; The GTEx Consortium, ; Wen, X.; Im, H. K.

10.1101/833210 — genetics — Posted on 2020-02-27

432 Gene expression profiling of corpus luteum reveals the importance of immune system during early pregnancy in domestic sheep.

Pokharel, K.; Peippo, J.; Weldenegodguad, M. B.; Honkatukia, M.; Li, M.-H.; Kantanen, J.

10.1101/673558 — genetics — Posted on 2020-02-27

433 Foxm1 regulates neuronal progenitor fate during spinal cord regeneration

Pelzer, D.; Phipps, L. S.; Thuret, R.; Baker, S. M.; Dorey, K.

10.1101/2020.02.26.962977 — developmental biology — Posted on 2020-02-27

434 Hypoxia-inducible lipid droplet-associated interacts with DGAT1 to promote lipid storage in hepatocytes

de la Rosa Rodriguez, M.; Gemmink, A.; van Weeghel, M.; Aoun, M. L.; Singh, R.; Borst, J. W.; Kersten, S.

10.1101/2020.02.26.966374 — biochemistry — Posted on 2020-02-27

435 Whole-body integration of gene expression and single-cell morphology

Vergara, H. M.; Pape, C.; Meechan, K.; Zinchenko, V.; Genoud, C.; Wanner, A. A.; Titze, B.; Templin, R.; Bertucci, P. Y.; Simakov, O.; Machado, P.; Savage, E. L.; Schwab, Y.; Friedrich, R. W.; Kreshuk, A.; Tischer, C.; Arendt, D.

10.1101/2020.02.26.961037 — cell biology — Posted on 2020-02-27

436 Myosin 1b Flattens and Prunes Branched Actin Filaments.

Pernier, J.; Morchain, A.; Caorsi, V.; Bertin, A.; Bousquet, H.; Bassereau, P.; Coudrier, E.

10.1101/2020.02.26.966663 — biophysics — Posted on 2020-02-27

437 Low atmospheric CO2 induces nocturnal carbon accumulation in the lycophyte genus Isoetes

Suissa, J. S.; Green, W. A.

10.1101/820514 — plant biology — Posted on 2020-02-27

438 Pollutants in Hong Kong Soils: Organochlorine Pesticides and Polychlorinated Biphenyls

Chung, M. K.; Hu, R.; Cheung, K. C.; Wong, M. H.

10.1101/2020.02.16.951541 — pharmacology and toxicology — Posted on 2020-02-27

439 Pollutants in Hong Kong Soils: As, Cd, Cr, Cu, Hg, Pb and Zn

Chung, M. K.; Cheung, K. C.; Wong, M. H.

10.1101/2020.02.16.951558 — pharmacology and toxicology — Posted on 2020-02-27

440 Grid cells encode local head direction

Gerlei, K.; Passlack, J.; Hawes, I.; Vandrey, B.; Stevens, H.; Papastathopoulos, I.; Nolan, M.

10.1101/681312 — neuroscience — Posted on 2020-02-27

441 The homeoprotein ENGRAILED-1 promotes motoneuron survival and motor functions

Vargas Abonce, S. E.; Leboeuf, M.; Moya, K. L.; Prochiantz, A. L.

10.1101/734020 — neuroscience — Posted on 2020-02-27

442 EEG-based detection of the locus of auditory attention with convolutional neural networks

Vandecappelle, S.; Deckers, L.; Das, N.; Hossein Ansari, A.; Bertrand, A.; Francart, T.

10.1101/475673 — neuroscience — Posted on 2020-02-27

443 Intensity and dose of neuromuscular electrical stimulation influence sensorimotor cortical excitability

Insausti-Delgado, A.; Lopez-Larraz, E.; Omedes, J.; Ramos-Murguialday, A.

10.1101/2020.02.21.957928 — neuroscience — Posted on 2020-02-27

444 Coevolution of retroviruses with SERINCs following whole-genome duplication divergence

Ramdas, P.; Bhardwaj, V.; Singh, A.; Vijay, N.; Chande, A.

10.1101/2020.02.24.962506 — microbiology — Posted on 2020-02-27

445 Polar mutagenesis of bacterial transcriptional units using Cas12a

Graffeuil, A.; Uhlin, B. E.; Cisneros, D. A.

10.1101/2020.02.21.959866 — microbiology — Posted on 2020-02-27

446 High contiguity de novo genome sequence assembly of Trifoliate yam (Dioscorea dumetorum) using long read sequencing

Siadjeu, C.; Pucker, B.; Viehöver, P.; Albach, D.; Weisshaar, B.

10.1101/2020.01.31.928630 — genomics — Posted on 2020-02-27

447 Host-adaptation in Legionellales is 2.4 Gya, coincident with eukaryogenesis

Hugoson, E.; Ammunet, T.; Guy, L.

10.1101/852004 — evolutionary biology — Posted on 2020-02-27

448 Quantifying transmission dynamics of acute hepatitis C virus infections in men having sex with men using phylodynamics

Danesh, G.; Virlogueux, V.; Ramiere, C.; Charre, C.; Cotte, L.; Alizon, S.

10.1101/689158 — evolutionary biology — Posted on 2020-02-27

449 Integrin-mediated adhesion in the unicellular holozoan Capsaspora owczarzaki

Parra-Acero, H.; Harcet, M.; Sanchez-Pons, N.; Casacuberta, E.; Brown, N. H.; Dudin, O.; Ruiz-Trillo, I.

10.1101/2020.02.27.967653 — evolutionary biology — Posted on 2020-02-27

450 Sp8 regulatory function in the limb bud ectoderm

Perez-Gomez, R.; Fernandez-Guerrero, M.; Campa, V.; Lopez-Gimenez, J. F.; Rada-Iglesias, A.; Ros, M. A.

10.1101/2020.02.26.965178 — developmental biology — Posted on 2020-02-27

451 Membrane architecture of pulmonary lamellar bodies revealed by post-correlation on-lamella cryo-CLEM

Klein, S.; Wimmer, B. H.; Winter, S. L.; Kolovou, A.; Laketa, V.; Chlanda, P.

10.1101/2020.02.27.966739 — cell biology — Posted on 2020-02-27

452 TRANSITION OF PODOSOMES INTO ZIPPER-LIKE STRUCTURES INMACROPHAGE-DERIVED MULTINUCLEATED GIANT CELLS

Balabiyev, A.; Podolnikova, N. P.; Mursalimov, A.; Lowry, D.; Newbern, J. M.; Roberson, R. W.; Ugarova, T. P.

10.1101/2020.02.26.966945 — cell biology — Posted on 2020-02-27

453 LSP1-myosin1e bi-molecular complex regulates focal adhesion dynamics and cell migration

Schaeringer, K.; Maxeiner, S.; Schalla, C.; Ruetten, S.; Zenke, M.; Sechi, A.

10.1101/2020.02.26.963991 — cell biology — Posted on 2020-02-27

454 Correlating single-molecule characteristics of the yeast aquaglyceroporin Fps1 with environmental perturbations directly in living cells

Shashkova, S.; Andersson, M.; Hohmann, S.; Leake, M. C.

10.1101/2020.02.27.967638 — biophysics — Posted on 2020-02-27

455 Widefield light sheet microscopy using an Airy beam combined with deep-learning super-resolution

Corsetti, S.; Wijesinghe, P.; Poulton, P. B.; Sakata, S.; Vyas, K.; Herrington, C. S.; Nylk, J.; Gasparoli, F.; Dholakia, K.

10.1101/2020.02.27.967547 — biophysics — Posted on 2020-02-27

456 VC1 catalyzes a key step in the biosynthesis of vicine from GTP in faba bean

Bjornsdotter, E.; Nadzieja, M.; Chang, W.; Escobar-Herrera, L.; Mancinotti, D.; Angra, D.; Khazaei, H.; Crocoll, C.; Vandenberg, A.; Stoddard, F. L.; O'Sullivan, D. M.; Stougaard, J.; Schulman, A. H.; Andersen, S. U.; Geu-Flores, F.

10.1101/2020.02.26.966523 — biochemistry — Posted on 2020-02-27

457 Nucleosomal embedding reshapes the dynamics of abasic sites

Bignon, E.; Claerbout, V.; Jiang, T.; Morell, C.; Gillet, N.; Dumont, E.

10.1101/2020.02.26.966366 — biochemistry — Posted on 2020-02-27

458 Meta-population structure and the evolutionary transition to multicellularity

Rose, C. J.; Hammerschmidt, K.; Pichugin, Y.; Rainey, P. B.

10.1101/407163 — evolutionary biology — Posted on 2020-02-27

459 Actin filament oxidation by MICAL1 suppresses protections from cofilin-induced disassembly

Wioland, H.; Fremont, S.; Guichard, B.; Echard, A.; JEGOU, A.; Romet-Lemonne, G.

10.1101/2020.02.26.966614 — biochemistry — Posted on 2020-02-27

460 Drivers of vascular plant species area relationships in British broadleaved woodlands and their effects on the species area curve

Guy, P.; Prentice, I. C.; Smart, S.

10.1101/2020.02.11.943282 — ecology — Posted on 2020-02-27

461 Predicting antibiotic-associated virulence of Pseudomonas aeruginosa using an ex-vivo lung biofilm model

Hassan, M. M.; Harrington, N. E.; Sweeney, E.; Harrison, F.

10.1101/2020.02.24.963173 — microbiology — Posted on 2020-02-27

462 dyngen: a multi-modal simulator for spearheading new single-cell omics analyses

Cannoodt, R.; Saelens, W.; Deconinck, L.; Saeys, Y.

10.1101/2020.02.06.936971 — bioinformatics — Posted on 2020-02-27

463 Intracranial-EEG evidence for medial temporal pole driving amygdala activity induced by multi-modal emotional stimuli

Sonkusare, S.; Nguyen, V. T.; Moran, R. J.; van der Meer, J. N.; Ren, Y.; Koussis, N.; Dionisio, S.; Breakspear, M.; Guo, C.

10.1101/2020.02.24.963801 — neuroscience — Posted on 2020-02-27

464 Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor

Olson, L. J.; Misra, S.; Ishihara, M.; Battaile, K.; Grant, O. C.; Sood, A.; Woods, R. J.; Kim, J.-J. P.; Tiemeyer, M.; Ren, G.; Sharp, J.; Dahms, N. M.

10.1101/2020.02.21.959957 — biochemistry — Posted on 2020-02-27

465 Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site.

Smith, S. J.; Towers, N.; Demetriou, K.; Mohun, T. J.

10.1101/2020.02.13.947424 — developmental biology — Posted on 2020-02-27

466 Reorganization of budding yeast cytoplasm upon energy depletion

Marini, G.; Nueske, E.; Leng, W.; Alberti, S.; Pigino, G.

10.1101/468454 — cell biology — Posted on 2020-02-27

467 A simple magnetic nanoparticles-based viral RNA extraction method for efficient detection of SARS-CoV-2

Zhao, Z.; Cui, H.; Song, W.; Ru, X.; Zhou, W.; Yu, X.

10.1101/2020.02.22.961268 — molecular biology — Posted on 2020-02-27

468 Spike protein binding prediction with neutralizing antibodies of SARS-CoV-2

Park, T.; Lee, S.-Y.; Kim, S.; Kim, M. J.; Kim, H. G.; Jun, S.; Kim, S. I.; Kim, B. T.; Park, E. C.; Park, D.

10.1101/2020.02.22.951178 — bioinformatics — Posted on 2020-02-27

469 Towards predictive nanotoxicology: from roundabout of molecular events to chronic inflammation prediction

Majaron, H.; Kokot, B.; Sebastijanovic, A.; Voss, C.; Podlipec, R.; Zawilska, P.; Berthing, T.; Ballester, C.; Danielsen, P. H.; Contini, C.; Ivanov, M.; Kriselj, A.; Cotar, P.; Zhou, Q.; Ponti, J.; Zhernovkov, V.; Schneemilch, M.; Pusnik, M.; Umek, P.; Pajk, S.; Joubert, O.; Schmid, O.; Urbancic, I.; Irmler, M.; Beckers, J.; Lobaskin, V.; Halappanavar, S.; Quirke, N.; Lyubartsev, A.; Vogel, U.; Koklic, T.; Stoeger, T.; Strancar, J.

10.1101/2020.02.27.966036 — molecular biology — Posted on 2020-02-27

470 Poincare Maps for Analyzing Complex Hierarchies in Single-Cell Data

Klimovskaia, A.; Lopez-Paz, D.; Bottou, L.; Nickel, M.

10.1101/689547 — bioinformatics — Posted on 2020-02-27

471 Melanopsin-dependent direct photic effects are equal to clock-driven effects in shaping the nychthemeral sleep-wake cycle

Hubbard, J.; Kobayashi Frisk, M.; Ruppert, E.; Tsai, J. W.; Fuchs, F.; Robin-Choteau, L.; Husse, J.; Calvel, L.; Eichele, G.; Franken, P.; Bourgin, P.

10.1101/2020.02.21.952077 — neuroscience — Posted on 2020-02-27

472 Unexpected variability of allelic imbalance estimates from RNA sequencing

Mendelevich, A.; Vinogradova, S.; Gupta, S.; Mironov, A. A.; Sunyaev, S.; Gimelbrant, A. A.

10.1101/2020.02.18.948323 — bioinformatics — Posted on 2020-02-27

473 Inhibitory midbrain neurons mediate decision making

Essig, J.; Hunt, J. B.; Felsen, G.

10.1101/2020.02.25.965699 — neuroscience — Posted on 2020-02-27

474 Proteomic cellular signatures of kinase inhibitor-induced cardiotoxicity: Mount Sinai DToxS LINCS Center Dataset

Xiong, Y.; Liu, T.; Chen, T.; Hansen, J.; Hu, B.; Chen, Y.; Jayaraman, G.; Schürer, S.; Vidovic, D.; Goldfarb, J.; Sobie, E. A.; Birtwistle, M. R.; Iyengar, R.; Li, H.; Azeloglu, E. U.

10.1101/2020.02.26.966606 — pharmacology and toxicology — Posted on 2020-02-26

475 RLP/K enrichment sequencing; a novel method to identify receptor-like protein (RLP) and receptor-like kinase (RLK) genes

Lin, X.; Armstrong, M.; Baker, K.; Wouters, D.; Visser, R.; Wolters, P. J.; Hein, I.; Vleeshouwers, V.

10.1101/2020.02.26.966085 — plant biology — Posted on 2020-02-26

476 "Prevalence of of ABO and Rhesus (Rh) Blood Groups in Eastern UP Population"

Kumar, P.; Rai, V.

10.1101/2020.02.26.965988 — genetics — Posted on 2020-02-26

477 Differential modulation of heat inducible genes across diverse genotypes and molecular cloning of a sHSP from Pearl millet

Sankar. S, M.; Satyavathi, C. T.; Barthakur, S.; Singh, S. P.; Kumar, R.; Prabhu, K. V.; Bharadwaj, C.; Soumya, S. L.

10.1101/2020.02.26.966184 — plant biology — Posted on 2020-02-26

478 Tongue thickness measured by ultrasonography is associated with tongue pressure in the Japanese elderly

Nakamori, M.; Imamura, E.; Fukuta, M.; Tachiyama, K.; Kamimura, T.; Hayashi, Y.; Matsushima, H.; Ogawa, K.; Nishino, M.; Hirata, A.; Mizoue, T.; Wakabayashi, S.

10.1101/2020.02.26.966226 — neuroscience — Posted on 2020-02-26

479 Are bivalves susceptible to domestication selection? Using starvation tolerance to test for potential trait changes in eastern oyster larvae

McFarland, K.; Plough, L. V.; Nguyen, M.; Hare, M. P.

10.1101/2020.02.26.966176 — evolutionary biology — Posted on 2020-02-26

480 Driving factors of conifer regeneration dynamics in eastern Canadian boreal old-growth forests

Martin, M.; Girona, M. M.; Morin, H.

10.1101/2020.02.26.966200 — ecology — Posted on 2020-02-26

481 Microtubule Defect Involved in 'Mitophagy Resistance' Under Subacute Oxidative Stress - Potential Mechanism for Cellular Inflammation

Tamura, T.; Yasuda, N.; Shakuo, T.; Kashiwagi, A.; Martyn, J. J. A.; Yokoyama, M.; Yasuhara, S.

10.1101/2020.02.26.966234 — cell biology — Posted on 2020-02-26

482 Maternal separation stress experienced by parents affects ovarian function in first generation of mice

khodamoradi, k.; Khosravizadeh, Z.; Amini-Khoei, H.; Hosseini, S. R.; Dehpour, A. R.; Hassanzadeh, G.; Kajal Khodamoradi, Zahra Khosravizadeh, Hossein Amini-Khoei ,Seyed Reza Hosseini, Ahmad Reza Dehpour,

10.1101/2020.02.26.966192 — cell biology — Posted on 2020-02-26

483 Feasibility of axon density metrics for brain asymmetry evaluation in the UK Biobank subsample

Maximov, I. I.; Westlye, L. T.

10.1101/2020.02.25.965293 — neuroscience — Posted on 2020-02-26

484 Accurate localization of linear probe electrodes across multiple brains

Liu, L. D.; Chen, S.; Economo, M. N.; Li, N.; Svoboda, K.

10.1101/2020.02.25.965210 — neuroscience — Posted on 2020-02-26

485 A pupil-linked arousal mechanism for deciding to engage in future physical effort

Kurniawan, I. T.; Grueschow, M.; Ruff, C. C.

10.1101/2020.02.25.964676 — neuroscience — Posted on 2020-02-26

486 Oxytocin Acts on Astrocytes in the Central Amygdala to Promote a Positive Emotional State

Wahis, J.; Kerspern, D.; Althammer, F.; Baudon, A.; Goyon, S.; Hagiwara, D.; Lefevre, A.; Boury-Jamot, B.; Bellanger, B.; Abatis, M.; Silva da Gouveia, M.; Benusiglio, D.; Eliava, M.; Rozov, A.; Weinstanto, I.; Knobloch-Bollmann, H. S.; Wang, H.; Pertin, M.; Inquimbert, P.; Pitzer, C.; Siemens, J.; Goumon, Y.; Boutrel, B.; Darbon, P.; Lamy, C. M.; Stern, J. E.; Decosterd, I.; Chatton, J.-Y.; Young, S. W.; Stoop, R.; Poisbeau, P.; Grinevich, V.; Charlet, A.

10.1101/2020.02.25.963884 — neuroscience — Posted on 2020-02-26

487 A virion-based assay for glycoprotein thermostability reveals key determinants of filovirus entry and its inhibition

Bortz, R. H.; Wong, A. C.; Grodus, M. G.; Recht, H.; Pulanco, M. C.; Lasso, G.; Anthony, S. J.; Mittler, E.; Jangra, R. K.; Chandran, K.

10.1101/2020.02.25.965772 — microbiology — Posted on 2020-02-26

488 No evidence for intermolecular recombination in human fibroblast and blood mtDNA from individuals with biparental mtDNA transmission

Gui, B.; Yang, Z.; Luo, S.; Slone, J.; Nagaraj, S.; Sadzewicz, L.; Tallon, L. J.; Huang, T.

10.1101/2020.02.26.941922 — genetics — Posted on 2020-02-26

489 Visual Experience is not Necessary for the Development of Face Selectivity in the Lateral Fusiform Gyrus

Ratan Murty, N. A.; Teng, S.; Beeler, D.; Mynick, A.; Oliva, A.; Kanwisher, N. G.

10.1101/2020.02.25.964890 — neuroscience — Posted on 2020-02-26

490 Tracking tendon fibers to their insertion - a 3D analysis of the Achilles tendon enthesis in mice

Sartori, J.; Stark, H.

10.1101/2020.02.25.964759 — zoology — Posted on 2020-02-26

491 Multi-proxy evidence for the impact of the Storegga Slide Tsunami on the early Holocene landscapes of the southern North Sea

Gaffney, V.; Fitch, S.; Bates, M.; Ware, R. L.; Kinnaird, T.; Gearey, B.; Hill, T.; Telford, R.; Batt, C.; Stern, B.; Whittaker, J.; Davies, S.; Ben Sharada, M.; Everett, R.; Cribdon, R.; Kistler, L.; Harris, S.; Kearney, K.; Walker, J.; Muru, M.; Hamilton, D.; Law, M.; Bates, R.; Allaby, R. G.

10.1101/2020.02.24.962605 — paleontology — Posted on 2020-02-26

492 Suppression of Inflammation Delays Hair Cell Regeneration and Functional Recovery Following Lateral Line Damage in Zebrafish Larvae

Zhang, R.; Liu, X.-P.; Li, Y.-J.; Chen, L.; Hu, B.

10.1101/2020.02.26.962753 — neuroscience — Posted on 2020-02-26

493 Antagonistic interactions subdue inter-species green-beard cooperation in bacteria.

Sathe, S.; Kuemmerli, R.

10.1101/2020.02.25.965665 — evolutionary biology — Posted on 2020-02-26

494 CRISPR-TAPE: protein-centric CRISPR guide design for targeted proteome engineering

Anderson, D. P.; Benns, H. J.; Tate, E. W.; Child, M. A.

10.1101/2020.02.26.965889 — bioinformatics — Posted on 2020-02-26

495 Recombinant production of active microbial transglutaminase in E. coli by using self-cleavable zymogen with mutated propeptide

Sato, R.; Minamihata, K.; Ariyoshi, R.; Taniguchi, H.; Kamiya, N.

10.1101/2020.02.25.965541 — bioengineering — Posted on 2020-02-26

496 Effective Biophysical Modeling of Cell Free Transcription and Translation Processes

Adhikari, A.; Vilkhovoy, M.; Vadhin, S.; Lim, H. E.; Varner, J.

10.1101/2020.02.25.964841 — systems biology — Posted on 2020-02-26

497 The vulnerability of working memory to distraction is rhythmic

Woestmann, M.; Lui, T. K.-Y.; Friese, K.-H.; Kreitewolf, J.; Naujokat, M.; Obleser, J.

10.1101/2020.02.26.965848 — neuroscience — Posted on 2020-02-26

498 Herpes Simplex Virus Mistyping due to HSV-1 x HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B

Casto, A. M.; Huang, M.-L.; Xie, H.; Jerome, K. R.; Wald, A.; Johnston, C.; Greninger, A. L.

10.1101/2020.02.25.965426 — genomics — Posted on 2020-02-26

499 Co-recruitment of relatives in a broadcast-spawning coral (Acropora hyacinthus) facilitates emergence of an inbred, genetically distinct group within a panmictic population

Barfield, S.; Davies, S. W.; Matz, M. V.

10.1101/2020.02.26.956680 — evolutionary biology — Posted on 2020-02-26

500 Dominance patterns in dynamic environments

Devi, A.; Jain, K.

10.1101/2020.02.25.965103 — evolutionary biology — Posted on 2020-02-26

501 The role of replication-removal spatial correlations and cellular replicative lifespan in corneal epithelium homeostasis

Strinkovsky, L.; Havkin, E.; Shalom-Feuerstein, R.; Savir, Y.

10.1101/2020.02.26.963199 — biophysics — Posted on 2020-02-26

502 Optogenetic control of gut bacterial metabolism

Hartsough, L. A.; Kotlajich, M. V.; Han, B.; Lin, C.-C. J.; Gambill, L.; Wang, M. C.; Tabor, J. J.

10.1101/2020.02.25.964866 — synthetic biology — Posted on 2020-02-26

503 Bayesian confidence for drift diffusion observers in dynamic stimuli tasks

Calder-Travis, J.; Bogacz, R.; Yeung, N.

10.1101/2020.02.25.965384 — animal behavior and cognition — Posted on 2020-02-26

504 Causes of death in newborn C57BL/6J mice

Peneda, S. C.; Morello, G. M.; Lamas, S.; Olsson, A.; Gilbert, C.

10.1101/2020.02.25.964551 — pathology — Posted on 2020-02-26

505 Top-down Control of Inhibition Reshapes Neural Dynamics Giving Rise to a Diversity of Computations

Chen, Z.; Padmanabhan, K.

10.1101/2020.02.25.964965 — neuroscience — Posted on 2020-02-26

506 Creative destruction: collisions and redundancy generate emergent sparseness on the mammal connectome

Hao, Y.; Graham, D. J.

10.1101/2020.02.25.964593 — neuroscience — Posted on 2020-02-26

507 Anxiety and the neurobiology of uncertain threat anticipation

Hur, J.; Smith, J. F.; DeYoung, K. A.; Anderson, A. S.; Kuang, J.; Kim, H. C.; Tillman, R. M.; Kuhn, M.; Fox, A. S.; Shackman, A. J.

10.1101/2020.02.25.964734 — neuroscience — Posted on 2020-02-26

508 What do adversarial images tell us about human vision?

Dujmovic, M.; Malhotra, G.; Bowers, J.

10.1101/2020.02.25.964361 — neuroscience — Posted on 2020-02-26

509 Nicotine exposure and neuronal activity regulate Golgi membrane dispersal and distribution

Govind, A. P.; Jeyifous, O.; Russell, T.; Vaasjo, L. O.; Yi, Z.; Weigel, A. V.; Newell, L.; Koranda, J. L.; Singh, K.; Valbuena, F.; Glick, B. S.; Mukherjee, J.; Lippincott-Schwartz, J.; Zhuang, X.; Green, W. N.

10.1101/2020.02.25.965285 — neuroscience — Posted on 2020-02-26

510 LRRK2 mutation alters behavioral, synaptic and non-synaptic adaptations to acute social stress

Guevara, C. A.; Matikainen-Ankney, B. A.; Kezunovic, N.; LeClair, K.; Conway, A. P.; Menard, C.; Flanigan, M. E.; Pfau, M.; Russo, S. J.; Benson, D. L.; Huntley, G. W.

10.1101/2020.02.25.965194 — neuroscience — Posted on 2020-02-26

511 Immune reactivity to neurofilaments and dipeptide repeats in ALS progression

Puentes, F.; Lombardi, V.; Lu, C.-H.; Yildiz, O.; Kang, A.; Nissim, A.; Fratta, P.; Isaacs, A.; Bobeva, Y.; Malaspina, A.

10.1101/2020.02.25.965236 — neuroscience — Posted on 2020-02-26

512 Bottom-up control of leakage in spectral electrophysiological source imaging via structured sparse bayesian learning

Gonzalez-Moreira, E.; Paz-Linares, D.; Areces-Gonzalez, A.; Wang, Y.; Li, M.; Harmony, T.; Valdes-Sosa, P. A.

10.1101/2020.02.25.964684 — neuroscience — Posted on 2020-02-26

513 Codon usage bias in radioresistant bacteria

Dilucca, M.; Giansanti, A.; Georgakilas, A.; Pavlopoulou, A.

10.1101/2020.02.25.964916 — molecular biology — Posted on 2020-02-26

514 Sensitive, highly multiplexed sequencing of microhaplotypes from the Plasmodium falciparum heterozygome

Tessema, S. K.; Hathaway, N. J.; Teyssier, N. B.; Murphy, M.; Aydemir, O.; Duarte, E. M.; Simone, W.; Colborn, J.; Saute, F.; Crawford, E.; Aide, P.; Bailey, J. A.; Greenhouse, B.

10.1101/2020.02.25.964536 — molecular biology — Posted on 2020-02-26

515 Measurement error and resolution in quantitative stable isotope probing: implications for experimental design

Sieradzki, E. T.; Koch, B. J.; Greenlon, A.; Sachdeva, R.; Malmstrom, R. R.; Mau, R. L.; Blazewicz, S. J.; Firestone, M. K.; Hofmockel, K.; Schwartz, E.; Hungate, B. A.; Pett-Ridge, J.

10.1101/2020.02.25.965764 — microbiology — Posted on 2020-02-26

516 Molecular characterization of unusual G10P genomic constellations and evidence of zooanthroponosis in bovines

Sawant, P.; Digraskar, S.; Varanasi, G.

10.1101/2020.02.25.965731 — microbiology — Posted on 2020-02-26

517 Bacteriophages targeting Acinetobacter baumannii capsule induce antimicrobial resensitization

Gordillo Altamirano, F. L.; Forsyth, J. H.; Patwa, R.; Kostoulias, X.; Trim, M.; Subedi, D.; Archer, S.; Morris, F. C.; Oliveira, C.; Kielty, L.; Korneev, D.; O'Bryan, M. K.; Lithgow, T. L.; Peleg, A. Y.; Barr, J. J.

10.1101/2020.02.25.965590 — microbiology — Posted on 2020-02-26

518 Analysis of healthy reference ranges for clinically relevant gut microbial indicators: A large web-based cohort study in Japan

Watanabe, S.; Kameoka, S.; Shinozaki, N. O.; Kubo, R.; Nishida, A.; Kuriyama, M.; Takeda, A. K.

10.1101/2020.02.25.965459 — microbiology — Posted on 2020-02-26

519 Convergent selection in antibody repertoires is revealed by deep learning

Friedensohn, S.; Neumeier, D.; Khan, T. A.; Csepregi, L.; Parola, C.; de Vries, A. R. G.; Erlach, L.; Mason, D. M.; Reddy, S. T.

10.1101/2020.02.25.965673 — immunology — Posted on 2020-02-26

520 Modular biomaterials vaccine technology protects against multiple pathogens and septic shock

Super, M.; Doherty, E. J.; Cartwright, M. J.; Seiler, B. T.; White, D. A.; Langellotto, F.; Stafford, A. G.; Dimitrakakis, N.; Karkada, M.; Graveline, A. R.; Horgan, C. L.; Lightbown, K. R.; Urena, F. R.; Yeager, C. D.; Rifai, S. A.; Dellacherie, M. O.; Li, A. W.; Jiang, A. R.; Chandrasekhar, V.; Scott, J. M.; Lightbown, S. L.; Ingber, D. E.; Mooney, D. J.

10.1101/2020.02.25.964601 — immunology — Posted on 2020-02-26

521 Heteroplasmy variability in individuals with biparentally inherited mitochondrial DNA

Slone, J.; Zou, W.; Luo, S.; Schmitt, E. S.; Chen, S. M.; Wang, X.; Brown, J.; Bromwell, M.; Chien, Y.-H.; Hwu, W.-L.; Fan, P.-C.; Lee, N.-C.; Wong, L.-J.; Zhang, J.; Huang, T.

10.1101/2020.02.26.939405 — genetics — Posted on 2020-02-26

522 An enhanced target-enrichment bait set for Hexacorallia provides phylogenomic resolution of the staghorn corals (Acroporidae) and close relatives.

Cowman, P. F.; Quattrini, A. M.; Bridge, T. C. L.; Watkins-Colwell, G. J.; Fadli, N.; Grinblat, M.; Roberts, T. E.; McFadden, C.; Miller, D. J.; Baird, A. H.

10.1101/2020.02.25.965517 — evolutionary biology — Posted on 2020-02-26

523 DGINN, an automated and highly-flexible pipeline for the Detection of Genetic INNovations on protein-coding genes

Picard, L.; Ganivet, Q.; Allatif, O.; Cimarelli, A.; Gueguen, L.; Etienne, L.

10.1101/2020.02.25.964155 — evolutionary biology — Posted on 2020-02-26

524 An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

Zewdu, R.; Mehrabad, E. M.; Ingram, K.; Jones, A.; Camolotto, S. A.; Mendoza, M. C.; Spike, B. T.; Snyder, E. L.

10.1101/2020.02.25.965004 — cancer biology — Posted on 2020-02-26

525 Quantifying Epigenetic Stability with Minimum Action Paths

Sood, A.; Zhang, B.

10.1101/2020.02.25.964726 — biophysics — Posted on 2020-02-26

526 SRRF 'n' TIRF - FCS: Simultaneous spatiotemporal super-resolution microscopy

Sankaran, J.; Balasubramanian, H.; Tang, W. H.; Ng, X. W.; Röllin, A.; Wohland, T.

10.1101/2020.02.26.965905 — biophysics — Posted on 2020-02-26

527 A rapid, accurate approach to inferring pedigrees in endogamous populations

Williams, C. M.; Scelza, B.; Gignoux, C. R.; Henn, B. M.

10.1101/2020.02.25.965376 — bioinformatics — Posted on 2020-02-26

528 Predicting Endometrial Cancer Subtypes and Molecular Features from Histopathology Images Using Multi-resolution Deep Learning Models

Hong, R.; Liu, W.; DeLair, D.; Fenyö, D.

10.1101/2020.02.25.965038 — bioinformatics — Posted on 2020-02-26

529 Discovering novel cell types across heterogeneous single-cell experiments

Brbic, M.; Zitnik, M.; Wang, S.; Pisco, A. O.; Altman, R. B.; Darmanis, S.; Leskovec, J.

10.1101/2020.02.25.960302 — bioinformatics — Posted on 2020-02-26

530 Methods for High-Fidelity Spectral Data Collection for Generating Ground Truth Data for Simulated Tissues

Gong, A. T.; Dulal, A.; Crane, M. M.; Reihsen, T.; Sweet, R. M.; Mendenhall, A. R.

10.1101/2020.02.25.964924 — bioengineering — Posted on 2020-02-26

531 High laboratory mouse pre-weaning mortality associated with litter overlap, advanced mother age, small and large litters

Morello, G. M.; Hultgren, J.; Peneda, S. C.; Whiltshire, M.; Thomas, A.; Wardle-Jones, H.; Brajon, S.; Gilbert, C.; Olsson, A.

10.1101/2020.02.25.953067 — animal behavior and cognition — Posted on 2020-02-26

532 Predicting missing links in global host-parasite networks

Farrell, M. J.; Elmasri, M.; Stephens, D. A.; Davies, T. J.

10.1101/2020.02.25.965046 — ecology — Posted on 2020-02-26

533 The Drosophila FUS ortholog cabeza promotes adult founder myoblast selection by Xrp1-dependent regulation of FGF signaling

Catinozzi, M.; Mallik, M.; Frickenhaus, M.; Been, M.; Sijlmans, C.; Kulshrestha, D.; Alexopoulos, I.; Weitkunat, M.; Schnorrer, F.; Storkebaum, E.

10.1101/2020.02.25.964932 — developmental biology — Posted on 2020-02-26

534 Semi-analytical dynamic modeling of DNA surface-hybridization via AC Electro-kinetic steering

Capaldo, P.; Dal Zilio, S.; Torre, V.; Yang, Y.

10.1101/2020.02.25.964809 — biophysics — Posted on 2020-02-26

535 Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and function

Good, N. M.; Fellner, M.; Demirer, K.; Hu, J.; Hausinger, R. P.; Martinez-Gomez, N. C. C.

10.1101/2020.02.25.964783 — biochemistry — Posted on 2020-02-26

536 Global Screening of Sentrin-Specific Protease Family Substrates in SUMOylation

Wang, Y.; Wu, X.; Ge, R.; Song, L.; Li, K.; Tian, S.; Cai, L.; Liu, M.; Shi, W.; Yu, G.; Zhen, B.; Wang, Y.; He, F.; Qin, J.; Ding, C.

10.1101/2020.02.25.964072 — biochemistry — Posted on 2020-02-26

537 Regulation of neuron-specific gene transcription by stress hormone signalling requires synaptic activity in zebrafish

Cunliffe, V. T.

10.1101/714873 — developmental biology — Posted on 2020-02-26

538 Genotype networks of 80 quantitative Arabidopsis thaliana phenotypes reveal phenotypic evolvability despite pervasive epistasis

Schweizer, G.; Wagner, A.

10.1101/2020.02.26.966390 — evolutionary biology — Posted on 2020-02-26

539 Movement of transposable elements contributes to cichlid diversity

Carleton, K. L.; Conte, M.; Malinsky, M.; Nandamuri, S. P.; Sandkam, B. A.; Meier, J. I.; Mwaiko, S.; Seehausen, O.; Kocher, T. D.

10.1101/2020.02.26.961987 — evolutionary biology — Posted on 2020-02-26

540 Repeated colonization of caves leads to phenotypic convergence in catfishes (Siluriformes: Trichomycterus) at a small geographical scale

Florez, J. S.; Cadena, C. D.; DoNascimiento, C.; Torres, M.

10.1101/2020.02.25.955179 — evolutionary biology — Posted on 2020-02-26

541 The generalist herbivore Tetranychus urticae (Koch) adapts to novel plant hosts through rapid evolution of metabolic resistance

Salehipourshirazi, G.; Bruinsma, K.; Ratlamwala, H.; Dixit, S.; Arbona, V.; Widemann, E.; Milojevic, M.; Jin, P.; Bensoussan, N.; Gomez-Cadenas, A.; Zhurov, V.; Grbic, M.; Grbic, V.

10.1101/2020.02.26.966481 — evolutionary biology — Posted on 2020-02-26

542 Exploring the impact of political regimes on biodiversity

Zizka, A.; Ryden, O.; Edler, D.; Klein, J.; Aronsson, H.; Perrigo, A.; Silvestro, D.; Jagers, S. C.; Lindberg, S. I.; Antonelli, A.

10.1101/2020.02.25.964429 — ecology — Posted on 2020-02-26

543 The impact of colonization history on the composition of ecological systems

Zhao, N.; Saavedra, S.; Liu, Y.-Y.

10.1101/2020.02.26.965715 — ecology — Posted on 2020-02-26

544 Regulation of NF-kappa B and cell death by bacterial gingipains

Urnowey, S.; Ansai, T.; Bitko, V.; Barik, S.

10.1101/2020.02.25.964585 — microbiology — Posted on 2020-02-26

545 Search for top-down and bottom-up drivers of latitudinal trends in insect herbivory in oak trees in Europe

Valdés-Correcher, E.; Moreira, X.; Augusto, L.; Barbaro, L.; Bouget, C.; Bouriaud, O.; Branco, M.; Centenaro, G.; Csóka, G.; Damestoy, T.; Dobrosavljevic, J.; Duduman, M.-L.; Dulaurent, A.-M.; Eötvös, C. B.; Faticov, M.; Ferrante, M.; Fürjes-Miko, Ágnes; Galmán, A.; Gossner, M. M.; Hampe, A.; Harvey, D.; Howe, A. G.; Kadiri, Y.; Kaennel-Dobbertin, M. K.-D.; Koricheva, J.; Kozel, A.; Kozlov, M. V.; Lövei, G. L.; Lupaştean, D.; Milanovic, S.; Mrazova, A.; Opgennoorth, L.; Pitkänen, J.-M.; Popova, A.; Popovic, M.; Prinzing, A.; Queloz, V.; Roslin,

10.1101/2020.02.25.964213 — ecology — Posted on 2020-02-26

546 Epigenetic reprogramming towards mesenchymal-epithelial transition in ovarian cancer-associated mesenchymal stem cells drives metastasis

Fan, H.; Atiya, H.; Wang, Y.; Pisanic, T.; Wang, J.; Shih, I.-M.; Foy, K.; Frisbie, L.; Chandler, C.; Shen, H.; Coffman, L. G.

10.1101/2020.02.25.964197 — cancer biology — Posted on 2020-02-26

547 Biogenic Amine Neurotransmitters Promote Eicosanoid Production And Protein Homeostasis

Rongo, C. G.; Joshi, K. K.; Matlack, T. L.; Pyonteck, S.; Menzel, R.

10.1101/2020.02.25.964189 — neuroscience — Posted on 2020-02-26

548 Analyzing Presymptomatic Tissue to Gain Insights into the Molecular and Mechanistic Origins of Late-Onset Degenerative Trinucleotide Repeat Disease

Mootha, V.; Corey, D.; Chu, Y.; Hu, J.; Liang, H.; Kanchwala, M.; Xing, C.; Beebe, W.; Bowman, C.; Gong, X.

10.1101/2020.02.25.964403 — molecular biology — Posted on 2020-02-26

549 Seasonal variation in physiology and shell condition of the pteropod Limacina retroversa in the Gulf of Maine relative to life cycle and carbonate chemistry.

Maas, A. E.; Lawson, G. L.; Bergan, A. J.; Wang, Z. A.; Tarrant, A. M.

10.1101/2020.02.25.964478 — ecology — Posted on 2020-02-26

550 Multiple roles for the ESCRT machinery in maintaining plasma membrane homeostasis

Schmidt, O.; Weyer, Y.; Sprenger, S.; Widerin, M. A.; Eising, S.; Baumann, V.; Angelova, M.; Loewith, R.; Stefan, C. J.; Hess, M. W.; Froehlich, F.; Teis, D.

10.1101/2020.02.25.964452 — cell biology — Posted on 2020-02-26

551 Accelerated single cell seeding in relapsed multiple myeloma

Landau, H. J.; Yellapantula, V.; Diamond, B. J.; Rustad, E. H.; Maclachlan, K.; Gundem, G.; Medina-Martinez, J.; Arango Ossa, J. E.; Levine, M.; Zhou, Y.; Rajya, K. L.; Baez, P.; Attiyeh, M.; Makohon-Moore, A.; Zhang, L.; Boyle, E. E.; Ashby, C.; Blaney, P.; Patel, M.; Zhang, Y.; Dogan, A.; Chung, D.; Giralt, S.; Lahoud, O. B.; Peled, J.; Scordo, M.; Shah, G.; Hassoun, H.; Korde, N. S.; Lesokhin, A. M.; Lu, S.; Mailankody, S.; Shah, U. A.; Smith, E.; Hultcrantz, M. L.; Ulaner, G.; van Rhee, F.; Morgan, G.; Landgren, O.; Papaemmanuil, E.; Iacobuzio-Donahue, C. A.; Maura, F.

10.1101/2020.02.25.963272 — cancer biology — Posted on 2020-02-26

552 SDip: A novel graph-based approach to haplotype-aware assembly based structural variant calling in targeted segmental duplications sequencing

Heller, D.; Vingron, M.; Church, G.; Li, H.; Garg, S.

10.1101/2020.02.25.964445 — bioinformatics — Posted on 2020-02-26

553 Argonaute Binding within 3'-Untranslated Regions Does Not Predict Gene Repression

Corey, D. R.; Chu, Y.; Kilikevicius, A.; Liu, J.; Yakota, S.; Johnson, K.

10.1101/2020.02.25.956623 — molecular biology — Posted on 2020-02-26

554 Epigenetic silencing of clustered tDNAs in Arabidopsis

Hummel, G.; Berr, A.; Graindorge, S.; Cognat, V.; Ubrig, E.; Pflieger, D.; Molinier, J.; Drouard, L.

10.1101/2020.02.26.962373 — plant biology — Posted on 2020-02-26

555 A non-canonical histone acetyltransferase targets intragenic enhancers and regulates plant architecture

Yang, X.; Yan, J.; Zhang, Z.; Lin, T.; Wang, B.; Wang, S.; Zhao, J.; Zhang, Z.; William, L.; Li, G.; Huang, S.

10.1101/2020.02.25.965475 — plant biology — Posted on 2020-02-26

556 Effects of breeding history and crop management on the root architecture of wheat

Fradgley, N.; Evans, G.; Biernaskie, J. M.; Cockram, J. S.; Marr, E. C.; Oliver, A. G.; Ober, E.; Jones, H.

10.1101/2020.02.25.964338 — plant biology — Posted on 2020-02-26

557 Evaluation of a new probiotic concept for broilers

Jorgensen, S. L.; Poulsen, L. L.; Bisgaard, M.; Christensen, H.

10.1101/2020.02.25.964460 — microbiology — Posted on 2020-02-26

558 A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies

Creanga, A.; Gillespie, R. A.; Fisher, B. E.; Andrews, S. F.; Hatch, L.; Stephens, T.; Tsybovsky, Y.; Crank, M. C.; McDermott, A. B.; Mascola, J. R.; Graham, B. S.; Kanekiyo, M.

10.1101/2020.02.24.963611 — immunology — Posted on 2020-02-26

559 A regulatory protein that represses sporulation in Clostridioides difficile

Martins, D.; Mendes, A. L.; Antunes, J.; Henriques, A. O.; Serrano, M.

10.1101/2020.02.25.964569 — microbiology — Posted on 2020-02-26

560 Gut microbiome, diet and symptom interactions in irritable bowel syndrome

Tap, J.; Störsrud, S.; Le Neve, B.; Cotillard, A.; Pons, N.; Dore, J.; Öhman, L.; Törnblom, H.; Derrien, M.; Simren, M.

10.1101/2020.02.25.964528 — microbiology — Posted on 2020-02-26

561 The expression of virulence by the Cryptococcus neoformans VNIa-5 lineage is plastic and associated with host immune background.

Trieu, H. P.; Thanh, T. L.; Duong, A. V.; Mai, T. N.; Huong, L. N. P.; Thwaites, G. E.; Johnson, E.; Vinh, C. N. V.; Ashton, P.; Day, J. N.

10.1101/2020.02.24.962134 — microbiology — Posted on 2020-02-26

562 Chloroplast genome of the nutmeg tree: Myristica fragrans Houtt. (Myristicaceae)

Mota de Oliveira, S.; Duijm, E.; ter Steege, H.

10.1101/2020.02.25.964122 — genetics — Posted on 2020-02-26

563 Mice lacking paternal expression of imprinted Grb10 are risk-takers

Dent, C. L.; Reinecker, K. D.; Ward, A.; Wilkins, J. F.; Humby, T.; Isles, A.

10.1101/2020.02.25.962399 — genetics — Posted on 2020-02-26

564 Inference of sexual selection from pairwise contests

Yu, T.; Clark, A. G.

10.1101/2020.02.25.964973 — evolutionary biology — Posted on 2020-02-26

565 Synthesis of diagnostic quality cancer pathology images

Levine, A. B.; Peng, J.; Farnell, D.; Nursey, M.; Wang, Y.; Naso, J. R.; Ren, H.; Farahani, H.; Chen, C.; Chiu, D.; Talhouk, A.; Sheffield, B.; Riazy, M.; Ip, P. P.; Parra-Herran, C.; Mills, A.; Singh, N.; Tessier-Cloutier, B.; Salisbury, T.; Lee, J.; Salcudean, T.; Jones, S. J. M.; Huntsman, D. G.; Gilks, C. B.; Yip, S.; Bashashati, A.

10.1101/2020.02.24.963553 — bioinformatics — Posted on 2020-02-26

566 Dividing labour in social microorganisms: coordinated or random specialisation?

Cooper, G. A.; Pena, J.; Liu, M.; West, S. A.

10.1101/2020.02.25.964643 — evolutionary biology — Posted on 2020-02-26

567 Predicting TUG score from gait characteristics based on video analysis and machine learning

Ma, J.

10.1101/2020.02.24.963686 — bioinformatics — Posted on 2020-02-26

568 Egg size does not universally predict embryonic resources and hatchling size across annual killifish species

Vrtilek, M.; Van Dooren, T. J.; Beaudard, M.

10.1101/2020.02.25.964411 — zoology — Posted on 2020-02-26

569 Proteomics, lipidomics, metabolomics and 16S rDNA sequencing of dental plaque from patients with diabetes and periodontal disease

Overmyer, K. A.; Rhoads, T.; Merrill, A. E.; Ye, Z.; Westphall, M. S.; Acharya, A.; Shukla, S.; Coon, J. J.

10.1101/2020.02.25.963967 — systems biology — Posted on 2020-02-26

570 Physiological properties and tailored feeds to support aquaculture of marbled crayfish in closed systems

Toenges, S.; Masagounder, K.; Gutekunst, J.; Lohbeck, J.; Miller, A. K.; Boehl, F.; Lyko, F.

10.1101/2020.02.25.964114 — physiology — Posted on 2020-02-26

571 Muscle progenitor cells are required for the regenerative response and prevention of adipogenesis after limb ischemia

Abbas, H.; Olivere, L. A.; Padgett, M. E.; Schmidt, C. A.; Gilmore, B. F.; Southerland, K. W.; McClung, J. M.; Kontos, C. D.

10.1101/2020.02.24.963777 — pathology — Posted on 2020-02-26

572 Whole Slide Preview Image Segmentation and Setup for Digital Pathology Scanners

Hosseini, M. S.; Lee, D.; Gershanik, D.; Lee, D.; Damaskinos, S.; Plataniotis, K. N.

10.1101/2020.02.24.963645 — pathology — Posted on 2020-02-26

573 Mycobacterium tuberculosis Rv3194c efficiently facilitates mycobacterial-lung epithelial interaction through its HA-binding site

Zhao, D.; Xu, C.; Lin, D.

10.1101/2020.02.24.963918 — microbiology — Posted on 2020-02-26

574 Two alveolin network proteins are essential for the subpellicular microtubules assembly and conoid anchoring to the apical pole of mature Toxoplasma gondii

Tosetti, N.; Dos Santos Pacheco, N.; Bertiaux, E.; Maco, B.; Bournonville, L.; Hamel, V.; Guichard, P.; Soldati-Favre, D.

10.1101/2020.02.25.962589 — microbiology — Posted on 2020-02-26

575 Genetic Profiling of Protein Burden and Nuclear Export Overload

Kintaka, R.; Makanae, K.; Kato, H.; Ohnuki, S.; Ohya, Y.; Andrews, B. J.; Boone, C.; Moriya, H.

10.1101/2020.02.25.962068 — genomics — Posted on 2020-02-26

576 Signatures of selection in the coral holobiont reveal complex adaptations to inshore environments driven by Holocene climate change

Cooke, I. R.; Ying, H.; Foret, S.; Bongaerts, P.; Strugnell, J. M.; Simakov, O.; Zhang, J.; Field, M. A.; Rodriguez-Lanetty, M.; Bell, S.; Bourne, D. G.; van Oppen, M.; Ragan, M. A.; Miller, D. J.

10.1101/2020.02.25.951905 — genomics — Posted on 2020-02-26

577 High-resolution animal tracking with integration of environmental information in aquatic systems

Francisco, F.; Nuehrenberg, P.; Jordan, A. L.

10.1101/2020.02.25.963926 — ecology — Posted on 2020-02-26

578 The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment

Legal, T.; Hayward, D.; Gluszek-Kustusz, A.; BLACKBURN, E.; Spanos, C.; Rappsilber, J.; Gruneberg, U.; Welburn, J. P.

10.1101/2020.02.25.962613 — cell biology — Posted on 2020-02-26

579 A liquid biopsy platform for detecting gene-gene fusions as glioma diagnostic biomarkers and drug targets

Palande, V.; Detroja, R.; Gorohovski, A.; Glass, R.; Flueh, C.; Kurtz, M.; Perez, S.; Raviv Shay, D.; Siegal, T.; Frenkel-Morgenstern, M.

10.1101/2020.02.25.963975 — cancer biology — Posted on 2020-02-26

580 Automated skull-stripping and segmentation with Multi-Task U-Net in large mouse brain MRI databases

De Feo, R.; Shantillo, A.; Sierra, A.; Valverde, J. M.; Grohn, O.; Giove, F.; Tohka, J.

10.1101/2020.02.25.964015 — bioinformatics — Posted on 2020-02-26

581 Purple bacteria as added-value protein ingredient in shrimp feed: Litopenaeus vannamei growth performance, and tolerance against Vibrio and ammonia stress

Alloul, A.; Wille, M.; Lucenti, P.; Van Stappen, G.; Bossier, P.; Vlaeminck, S. E.

10.1101/2020.02.25.964007 — bioengineering — Posted on 2020-02-26

582 Potassium channels, megapolarization, and water pore formation are key determinants for cationic cell-penetrating peptide translocation into cells

Trofimenko, E.; Grasso, G.; Heulot, M.; Chavalier, N.; Deriu, M. A.; Dubuis, G.; Arribat, Y.; Serulla, M.; Michel, S.; Vantomme, G.; Ory, F.; Puyal, J. P.; Amati, F.; Luthi, A.; Danani, A.; Widmann, C.

10.1101/2020.02.25.963017 — cell biology — Posted on 2020-02-26

583 Mesoscopic-scale functional networks in the primate amygdala

Morrow, J. K.; Cohen, M. X.; Gothard, K. M.

10.1101/2020.02.24.963587 — neuroscience — Posted on 2020-02-26

584 General anaesthesia disrupts complex cortical dynamics in response to intracranial electrical stimulation in rats

Arena, A.; Comolatti, R.; Thon, S.; Casali, A. G.; Storm, J. F.

10.1101/2020.02.25.964056 — neuroscience — Posted on 2020-02-26

585 Using Major Depression Polygenic Risk Scores to Explore the Depressive Symptom Continuum

Jermy, B. S.; Hagenaars, S. P.; Glanville, K. P.; Coleman, J. R.; Howard, D. M.; Breen, G.; Vassos, E.; Lewis, C. M.

10.1101/2020.02.25.962704 — genetics — Posted on 2020-02-26

586 Convergent evolution of niche structure in Northeast Pacific kelp forests

Starko, S.; Demes, K.; Neufeld, C. J.; Martone, P. T.

10.1101/2020.02.24.963421 — ecology — Posted on 2020-02-26

587 Mustache: Multi-scale Detection of Chromatin Loops from Hi-C and Micro-C Maps using Scale-Space Representation

Ardakany, A. R.; Gezer, H. T.; Lonardi, S.; Ay, F.

10.1101/2020.02.24.963579 — bioinformatics — Posted on 2020-02-26

588 Lossless Immunocytochemistry using Photo-polymerized Hydrogel Thin-films

Lee, J. H.; Santoso, A. T.; Park, E. S.; Matthews, K.; Duffy, S. P.; Ma, H.

10.1101/2020.02.24.963793 — bioengineering — Posted on 2020-02-26

589 B cells expressing authentic naive human VRC01-class BCRs can be primed and recruited to germinal centers in multiple independent mouse models

10.1101/2020.02.24.963629 — immunology — Posted on 2020-02-26

590 A streamlined workflow for automated cryo focused ion beam milling

Tacke, S.; Erdmann, P.; Wang, Z.; Klumpe, S.; Grange, M.; Kriz, R.; Dolnik, M.; Mitchels, J.; Plitzko, J.; Raunser, S.

10.1101/2020.02.24.963033 — molecular biology — Posted on 2020-02-26

591 Genomic Prediction with Genotype by Environment Interaction Analysis for Kernel Zinc Concentration in Tropical Maize Germplasm

Lee, M.; Mageto, E. K.; Crossa, J.; Perez-Rodriguez, P.; Dhliwayo, T.; Palacios, N.; Guo, R.; Zhang, X.; San Vicente, F.; Vemuri, H.

10.1101/2020.02.24.963090 — genetics — Posted on 2020-02-26

592 Mechanical Heterogeneity in the Bone Microenvironment as Characterised by Atomic Force Microscopy

Hobbs, J. K.; Chen, X.; Mullin, N.; Hawkins, R.; Brown, N. J.; Holen, I.; Hughes, R.

10.1101/2020.02.25.964791 — biophysics — Posted on 2020-02-26

593 Structural comparative analysis of GLUT1 and GLUT3 reveal role of SP motif in transport regulation

Custodio, T. F.; Paulsen, P. A.; Pedersen, B. P.

10.1101/2020.02.24.962258 — biochemistry — Posted on 2020-02-26

594 Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the PPARγ-homologue E75B in Drosophila

Zipper, L.; Jassmann, D.; Görlich, B.; Reiff, T.

10.1101/2020.02.24.962829 — developmental biology — Posted on 2020-02-26

595 Automatic classification of constitutive and non-constitutive metabolites with gcProfileMakeR

Egea-Cortines, M.; Perez-Sanz, F.; Ruiz-Hernandez, V.; Terry, M. I.; Arce-Gallego, S.; Weiss, J.; Navarro, P. J.

10.1101/2020.02.24.963058 — bioinformatics — Posted on 2020-02-26

596 Bacteria Use Structural Imperfect Mimicry To Hijack The Host Interactome

Torrent, M.; Sanchez de Groot, N.

10.1101/2020.02.24.962944 — microbiology — Posted on 2020-02-26

597 PCV2 aggravated SS2 infection directly showed from differentially expressed proteome of PK15 cells.

Tan, J.; Xiao, Q.; Li, X.; Fan, H.; He, K.

10.1101/2020.02.24.962738 — microbiology — Posted on 2020-02-26

598 Toxoplasma GRA15 limits parasite growth in IFNγ-activated fibroblasts through TRAF ubiquitin ligases

Mukhopadhyay, D.; Sangare, L. O.; Braun, L.; Hakimi, M. A.; Saeij, J. P.

10.1101/2020.02.24.963496 — immunology — Posted on 2020-02-26

599 Reconstruction and dynamics of human intestinal microbiome observed in situ

Liu, X.; Dai, M.; Ma, Y.; Zhao, N.; Zhang, H.; Xiang, L.; Tian, H.; Shui, G.; Zhang, F.; Wang, J.

10.1101/2020.02.25.964148 — microbiology — Posted on 2020-02-26

600 Contact patterns reveal a stable dynamic community structure with fission-fusion dynamics in wild house mice

Liechti, J. I.; Qian, B.; Koenig, B.; Bonhoeffer, S. I.

10.1101/2020.02.24.963512 — ecology — Posted on 2020-02-26

601 Identification of immunological features enables survival prediction of muscle-invasive bladder cancer patients using machine learning

Gavriel, C. G.; Dimitriou, N.; Brieu, N.; Nearchou, I. P.; Arandjelovic, O.; Schmidt, G.; Harrison, D. J.; Caie, P. D.

10.1101/2020.02.24.963181 — cancer biology — Posted on 2020-02-26

602 SR-B1 uptake of HDL promotes prostate cancer proliferation and tumor progression

Traughber, C. A.; Opoku, E.; Brubaker, G.; Major, J.; Lu, H.; Lorkowski, S. W.; Neumann, C.; Hardaway, A.; Chung, Y.-M.; Gulshan, K.; Sharifi, N.; Brown, J. M.; Smith, J. D.

10.1101/2020.02.24.963454 — cancer biology — Posted on 2020-02-26

603 Stress and behavioral correlates in the head-fixed method

Juczewski, K.; Koussa, J. A.; Kesner, A. J.; Lee, J. O.; Lovinger, D. M.

10.1101/2020.02.24.963371 — physiology — Posted on 2020-02-26

604 A neural network for online spike classification that improves decoding accuracy

Issar, D.; Williamson, R.; Khanna, S.; Smith, M. A.

10.1101/722934 — neuroscience — Posted on 2020-02-25

605 The transcriptional landscape of Venezuelan equine encephalitis virus infection

Yao, Z.; Zanini, F.; Kumar, S.; Panpradist, N.; Muniz, A.; Quake, S. R.; Einav, S.

10.1101/2020.02.18.955393 — microbiology — Posted on 2020-02-25

606 Thermogenic hydrocarbons fuel a redox stratified subseafloor microbiome in deep sea cold seep sediments

Dong, X.; Rattray, J. E.; Campbell, D. C.; Webb, J.; Chakraborty, A.; Adebayo, O.; Matthews, S.; Li, C.; Fowler, M.; Macdonald, A.; Groves, R. A.; Lewis, I. A.; Wang, S. H.; Mayumi, D.; Greening, C.; Hubert, C. R. J.

10.1101/2020.02.02.928283 — microbiology — Posted on 2020-02-25

607 Response to Tavares et al., "Covariation analysis with improved parameters reveals conservation in lncRNA structures"

Rivas, E.; Eddy, S. R.

10.1101/2020.02.18.955047 — bioinformatics — Posted on 2020-02-25

608 Genetic structure, function and evolution of capsule biosynthesis loci in Vibrio parahaemolyticus

Bian, S.; Wenhong, Z.; Li, Q.; Li, Y.; Wong, N.-K.; Jiang, M.; Zuo, L.; Hu, Q.; Li, L.

10.1101/2020.02.25.964247 — microbiology — Posted on 2020-02-25

609 Pseudomonas aeruginosa isolates co-incubated with Acanthamoeba castellanii exhibit phenotypes similar to chronic cystic fibrosis isolates

Leong, W.; Lutz, C.; Williams, J.; Poh, Y. H.; Yeo, B. K. Y.; Chua, C.; Rice, S. A.; Givskov, M.; Sanderson-Smith, M.; McDougald, D.

10.1101/2020.02.25.964320 — microbiology — Posted on 2020-02-25

610 ARF suppresses 5'-terminal oligopyrimidine mRNA translation

Cottrell, K. A.; Chiou, R. C.; Weber, J. D.

10.1101/2020.02.07.939165 — cell biology — Posted on 2020-02-25

611 Identification of novel RNA Polymerase II CTD interaction sites on the mRNA Capping Enzyme

Bage, M. G.; Almohammed, R.; Cowling, V. H.; Pisliakov, A. V.

10.1101/2020.02.25.964700 — biophysics — Posted on 2020-02-25

612 Projection of orthogonal tiling from the retina to the visual cortex

Jang, J.; Song, M.; Kim, G.; Paik, S.-B.

10.1101/2020.02.24.963785 — neuroscience — Posted on 2020-02-25

613 Clinical Epidemiology of congenital heart diseases in dogs: prevalence, popularity and volatility throughout twenty years of clinical practice

Brambilla, P. G.; Polli, M.; Pradelli, D.; Papa, M.; rizzi, R.; Bagardi, M.; Bussadori, C.

10.1101/2020.02.25.964262 — pathology — Posted on 2020-02-25

614 An original structural fold underlies the multitask P1, a silencing suppressor encoded by the Rice yellow mottle virus

Poignavent, V.; Hoh, F.; Terral, G.; Yang, Y.; Gillet, F.-x.; Kim, J. H.; Allemand, F.; Lacombe, E.; CIANFERANI, S.; Brugidou, C.; Demene, H.; Vignols, F.

10.1101/2020.02.24.963488 — pathology — Posted on 2020-02-25

615 Intravenous edaravone plus therapeutic hypothermia offers limited neuroprotection in the hypoxic-ischaemic newborn piglet

Yamato, S.; Nakamura, S.; Htun, Y.; Nakamura, M.; Jinnai, W.; Nakao, Y.; Mitsuie, T.; Koyano, K.; Wakabayashi, T.; Morimoto, A. H.; Sugino, M.; Iwase, T.; Kondo, S. I.; Yasuda, S.; Ueno, M.; Miki, T.; Kusaka, T.

10.1101/2020.02.25.964288 — neuroscience — Posted on 2020-02-25

616 Mucosal vaccination with CysVac2/Advax induces Th17 lung-resident CD4+ T cells and interleukin-17-dependant protection against Mycobacterium tuberculosis infection

Counoupas, C.; Ferrell, K.; Ashhurst, A.; Bhattacharyya, N.; Nagalingam, G.; Feng, C.; Petrovsky, N.; Britton, W. J.; Triccas, J. A.

10.1101/2020.02.25.964312 — immunology — Posted on 2020-02-25

617 Long title: The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities

10.1101/2020.02.25.964254 — genetics — Posted on 2020-02-25

618 Whole genome analysis reveals aneuploidies in early pregnancy loss in the horse

Shilton, C. A.; Kahler, A.; Davis, B. W.; Crabtree, J. R.; Crowhurst, J.; McGladdery, A. J.; Wathes, D. C.; Raudsepp, T.; de Mestre, A. M.

10.1101/2020.02.25.964239 — genetics — Posted on 2020-02-25

619 The need to harmonize insecticide resistance testing: methodology, intensity concentrations and molecular mechanisms evaluated in Aedes aegypti populations in Central America and Hispaniola

Ledoux, S.; Torres Gutierrez, C.; Lobo, N. F.; Murillo, E. M.; Perez, S.; Guerra, R.; Chanquin Avendano, S.; Orellana Herrera, A. G.; Mendoza, A.; Escobar, D.; Guzman Contreras, G.; Rivera, M.; Ventura, G.; Anagonou, R.; Pierre-Louis, E.; Yurrita, C.; Lopez Hun, F. J.; Duque, C.; Romero, E.; Lovin, D. D.; Cunningham, J. M.; Dengela, D.; Belemvire, A.; Stewart, K.; Grisales, N.

10.1101/2020.02.25.964270 — ecology — Posted on 2020-02-25

620 Profiling of the reprogramome and quantification of fibroblast reprogramming to pluripotency

Hu, K.; Ianov, L.; Crossman, D.

10.1101/2020.02.25.964296 — cell biology — Posted on 2020-02-25

621 The predicted RNA-binding protein ETR-1/CELF1 acts in muscles to regulate neuroblast migration in Caenorhabditis elegans

Ochs, M. E.; Josephson, M. P.; Lundquist, E. A.

10.1101/2020.02.25.965277 — developmental biology — Posted on 2020-02-25

622 Use of relevancy and complementary information for discriminatory gene selection from high-dimensional cancer data

Haque, M. N.; Sharmin, S.; Ali, A. A.; Sajib, A. A.; Shoyaib, M.

10.1101/2020.02.25.964304 — bioinformatics — Posted on 2020-02-25

623 Key histone chaperones have distinct roles in replisome progression and genomic stability

Tsirkas, I.; Dovrat, D.; Lei, Y.; Kalyva, A.; Lotysh, D.; Li, Q.; Aharoni, A.

10.1101/2020.02.25.964221 — cell biology — Posted on 2020-02-25

624 Normalizing and denoising protein expression data from droplet-based single cell profiling

Mulè, M. P.; Martins, A. J.; Tsang, J. S.

10.1101/2020.02.24.963603 — bioinformatics — Posted on 2020-02-25

625 Intracranial-EEG evidence for medial temporal pole driving amygdala activity in multi-modal emotional stimuli

Sonkusare, S.; Nguyen, V. T.; Moran, R. J.; van der Meer, J. N.; Ren, Y.; Koussis, N.; Dionisio, S.; Breakspear, M.; Guo, C.

10.1101/2020.02.24.963801 — neuroscience — Posted on 2020-02-25

626 Three-dimensional synaptic organization of the human hippocampal CA1 field

Montero-Crespo, M.; Dominguez-Alvaro, M.; Rondon-Carrillo, P.; Alonso-Nanclares, L.; DeFelipe, J.; Blazquez-Llorca, L.

10.1101/2020.02.25.964080 — neuroscience — Posted on 2020-02-25

627 Emotional contagion of pain across different social cues shares common and process-specific neural representations

Zhou, F.; Li, J.; Zhao, W.; Xu, L.; Zheng, X.; Fu, M.; Yao, S.; Kendrick, K. M.; Wager, T. D.; Becker, B.

10.1101/2020.02.24.963595 — neuroscience — Posted on 2020-02-25

628 Projection of orthogonal tiling from the retina to the visual cortex

Jang, J.; Song, M.; Paik, S.-B.

10.1101/2020.02.24.963785 — neuroscience — Posted on 2020-02-25

629 Connectomic analysis reveals an interneuron with an integral role in the retinal circuit for night vision

Park, S. J. H.; Lieberman, E. M.; Ke, J.-B.; Rho, N.; Ghorbani, P.; Rahmani, P.; Lee, H.-L.; Jun, N. Y.; Kim, I.-J.; Briggman, K. L.; Demb, J.; Singer, J. H.

10.1101/2020.02.24.963868 — neuroscience — Posted on 2020-02-25

630 The wiring logic of an identified serotonergic neuron that spans sensory networks

Coates, K. E.; Calle-Schuler, S. A.; Helmick, L. M.; Knotts, V. L.; Martik, B. N.; Salman, F.; Warner, L. T.; Valla, S. V.; Bock, D. D.; Dacks, A. M.

10.1101/2020.02.24.963660 — neuroscience — Posted on 2020-02-25

631 Whole brain optoacoustic tomography reveals strain-specific regional beta-amyloid densities in Alzheimer`s disease amyloidosis models

Ni, R.; Dean-Ben, X. L.; Kirschenbaum, D.; Rudin, M.; Chen, Z.; Crimi, A.; Voigt, F.; Nilsson, P. R.; Helmchen, F.; Nitsch, R. M.; Aguzzi, A.; Razansky, D.; Klohs, J.

10.1101/2020.02.25.964064 — neuroscience — Posted on 2020-02-25

632 Transparent and flexible ECoG electrode arrays based on silver nanowire networks for neural recordings

Neto, J. P.; Costa, A.; Pinto, J. V.; Marques-Smith, A.; Costa, J.; Martins, R.; Fortunato, E.; Kampff, A. R.; Barquinha, P.

10.1101/2020.02.24.962878 — neuroscience — Posted on 2020-02-25

633 Expecting the unexpected: the paranoid style of belief updating across species

Reed, E. J.; Uddenberg, S.; Mathys, C.; Taylor, J. R.; Groman, S.; Corlett, P. R.

10.1101/2020.02.24.963298 — neuroscience — Posted on 2020-02-25

634 C. elegans processes sensory information to choose between freeloading and self-defense strategies

Schiffer, J.; Servello, F.; Heath, W.; Amrit, F. R. G.; Stumbur, S.; Johnsen, S. B.; Stanley, J. A.; Tam, H.; Brennan, S.; McGowan, N.; Vogelaar, A.; Xu, Y.; Serkin, W.; Ghazi, A.; Apfeld, J.

10.1101/2020.02.24.963637 — neuroscience — Posted on 2020-02-25

635 Separating Measured Genetic and Environmental Effects: Evidence Linking Parental Genotype and Adopted Child Outcomes

Domingue, B. W.; Fletcher, J.

10.1101/698464 — genomics — Posted on 2020-02-25

636 Predicting Vibrio cholerae infection and disease severity using metagenomics in a prospective cohort study

Levade, I.; Saber, M. M.; Midani, F. S.; Chowdhury, F.; Khan, A. I.; Begum, Y.; Ryan, E. T.; David, L. A.; Calderwood, S. B.; Harris, J. B.; LaRocque, R. C.; Qadri, F.; Shapiro, B. J.; Weil, A. A.

10.1101/2020.02.25.960930 — microbiology — Posted on 2020-02-25

637 The Evolution of Mass Cell Suicide in Bacterial Warfare

Granato, E. T.; Foster, K. R.

10.1101/2020.02.25.959577 — microbiology — Posted on 2020-02-25

638 Diet Post-translationally Modifies The Gut Microbial Proteome To Modulate Renal Function

Lobel, L.; Cao, Y. G.; Glickman, J. N.; Garrett, W. S.

10.1101/2020.02.25.964957 — microbiology — Posted on 2020-02-25

639 X-ray and solution structures of human beta-2 glycoprotein I reveal a new mechanism of autoantibody recognition

Ruben, E.; Planer, W.; Chinnaraj, M.; Chen, Z.; Zuo, X.; Pengo, V.; De Filippis, V.; Alluri, R.; McCrae, K.; Macor, P.; Tedesco, F.; Pozzi, N.

10.1101/2020.02.25.963314 — biochemistry — Posted on 2020-02-25

640 Standard Flow Multiplexed Proteomics (SFloMPro). An Accessible and Cost-Effective Alternative to NanoLC Workflows

Jenkins, C.; Orsburn, B.

10.1101/2020.02.25.964379 — biochemistry — Posted on 2020-02-25

641 Functional remodeling of lysosomes by type I interferon modifies host defense

Zhang, H.; Zoued, A.; Liu, X.; Sit, B.; Waldor, M. K.

10.1101/2020.02.25.965061 — cell biology — Posted on 2020-02-25

642 Big Defensin ApBD1 from the scallop Argopecten purpuratus is an antimicrobial peptide which entraps bacteria through nanonets formation

Stambuk, F.; Ojeda, C.; Schmitt, P.

10.1101/2020.02.25.965327 — immunology — Posted on 2020-02-25

643 The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development

Laidlaw, B. J.; Duan, L.; Xu, Y.; Vazquez, S. E.; Cyster, J. G.

10.1101/2020.02.25.965301 — immunology — Posted on 2020-02-25

644 Bilateral alignment of receptive fields in the olfactory cortex points to non-random connectivity

Grimaud, J.; Dorrell, W.; Pehlevan, C. N.; Murthy, V. N.

10.1101/2020.02.24.960922 — neuroscience — Posted on 2020-02-25

645 TRPV1 expressed throughout the arterial circulation enables inflammatory vasoconstriction

Phan, T. X.; Ton, H. T.; Gulyas, H.; Porszasz, R.; Toth, A.; Russo, R.; Kay, M. W.; Sahibzada, N.; Ahern, G. P.

10.1101/2020.02.04.934117 — physiology — Posted on 2020-02-25

646 Toxic stress-specific cytoprotective responses regulate learned behavioral decisions in C. elegans

Hajdu, G.; Gecse, E.; Taisz, I.; Mora, I.; Soti, C.

10.1101/2020.02.24.962381 — neuroscience — Posted on 2020-02-25

647 Global Motion Detection and Censoring in High-Density Diffuse Optical Tomography

Sherafati, A.; Snyder, A. Z.; Eggebrecht, A. T.; Bergonzi, K. M.; Burns-Yocum, T. M.; Lugar, H. M.; Ferradal, S. L.; Robichaux-Viehoever, A.; Smyser, C. D.; Palanca, B. J.; Hershey, T.; Culver, J. P.

10.1101/2020.02.22.961219 — neuroscience — Posted on 2020-02-25

648 Object selection by automatic spreading of top-down attentional signals in V1

Ekman, M.; Roelfsema, P.; de Lange, F.

10.1101/2020.02.24.962761 — neuroscience — Posted on 2020-02-25

649 The anticipation and perception of affective touch in women with and recovered from Anorexia Nervosa

Crucianelli, L.; Demartini, B.; Goeta, D.; Nistico, V.; Saramandi, A.; Bertelli, S.; Todisco, P.; Gambini, O.; Fotopoulou, A.

10.1101/2020.02.23.961367 — neuroscience — Posted on 2020-02-25

650 The Transition from Acute to Chronic Pain: Dynamic Epigenetic Reprogramming of the Mouse Prefrontal Cortex up to One Year Following Nerve Injury

Topham, L.; Gregoire, S.; Kang, H.; Salmon, M.; Lax, E.; Millecamps, M.; Szyf, M.; Stone, L.

10.1101/2020.02.22.956128 — neuroscience — Posted on 2020-02-25

651 No Vergence Size Constancy

Linton, P.

10.1101/2020.02.23.961649 — neuroscience — Posted on 2020-02-25

652 Learning differentially reorganizes brain activity and connectivity

Bertolero, M. A.; Adebimpe, A.; Khambhati, A. N.; Mattar, M. G.; Thompson-Schill, S. L.; Bassett, D. S.

10.1101/2020.02.23.961623 — neuroscience — Posted on 2020-02-25

653 Beyond locomotion: in the mouse the mapping between sensations and behaviours unfolds in a higher dimensional space

Storchi, R.; Cootes, T. F.; Lucas, R. J.

10.1101/2020.02.24.961565 — animal behavior and cognition — Posted on 2020-02-25

654 First record of a Nathusius' pipistrelle (Pipistrellus nathusii) overwintering at a latitude above 60°N

Blomberg, A. S.; Vasko, V. V.; Salonen, S.; Petersons, G.; Lilley, T. M.

10.1101/2020.02.24.962563 — ecology — Posted on 2020-02-25

655 The glue produced by Drosophila melanogaster for pupa adhesion is universal

Borne, F.; Kovalev, A.; Gorb, S.; Courtier-Orgogozo, V.

10.1101/2019.12.19.882761 — biophysics — Posted on 2020-02-25

656 Successful Correction of ALD Patient-derived iPSCs Using CRISPR/Cas9

Jung, E. S.; Quan, Z.; Chang, M.-Y.; Kim, J. H.; Kim, S. H.; You, S.; Kim, D.-S.; Jang, J.; Lee, S.-H.; Kim, H. H.; Kang, H.-C.

10.1101/2020.02.23.962118 — neuroscience — Posted on 2020-02-25

657 Evolution of the standard genetic code

Yarus, M.

10.1101/2020.02.20.958546 — evolutionary biology — Posted on 2020-02-25

658 A 3D structural affinity model for multi-epitope in silico germinal center simulations

Robert, P. A.; Meyer-Hermann, M.

10.1101/766535 — systems biology — Posted on 2020-02-25

659 A retrospective analysis of gender parity in scientific authorship in a biomedical research centre

Dam, R.; Shah, S. G. S.; Milano, M. J.; Edmunds, L. D.; Henderson, L. R.; Hartley, C.; Coxall, O.; Ovseiko, P. V.; Buchan, A. M.; Kiparoglou, V.

10.1101/2020.02.24.962175 — scientific communication and education — Posted on 2020-02-25

660 Neutral auditory words immediately followed by painful electric shock show reduced next-day recollection

Norton, C. M.; Ibinson, J. W.; Pcola, S. J.; Reder, L. M.; Fiez, J. A.; Vogt, K. M.

10.1101/2020.02.24.963165 — neuroscience — Posted on 2020-02-25

661 Neuroimaging-based Individualized Prediction of Cognition and Behavior for Mental Disorders and Health: Methods and Promises

SUI, J.; Jiang, R.; Bustillo, J.; Calhoun, V. D.

10.1101/2020.02.22.961136 — neuroscience — Posted on 2020-02-25

662 Continuous force measurements reveal no inhibitory control deficits in Parkinson's disease

Pickering, J. S.; McBride, J.; Leroi, I.; Poliakoff, E.

10.1101/809780 — neuroscience — Posted on 2020-02-25

663 Predicting antibiotic-associated virulence of Pseudomonas aeruginosa using an ex-vivo lung biofilm model

Hassan, M. M.; Harrington, N. E.; Sweeney, E.; Harrison, F. M.

10.1101/2020.02.24.963173 — microbiology — Posted on 2020-02-25

664 EvoProDom: Evolutionary model of protein families by means of translocations of protein domains

Carmi, G.; Gorohovski, A.; Frenkel-Morgenstern, M.

10.1101/2020.02.23.961532 — evolutionary biology — Posted on 2020-02-25

665 Current and potential contributions of the Gulf of Lion Fisheries Restricted Area to fisheries sustainability in the NW Mediterranean Sea

Vilas, D.; Coll, M.; Corrales, X.; Steenbeek, J.; Piroddi, C.; Macias, D.; Ligas, A.; Sartor, P.; Claudet, J.

10.1101/2020.02.22.960914 — ecology — Posted on 2020-02-25

666 Partitioning the colonization and extinction components of beta diversity: Spatiotemporal species turnover across disturbance gradients

Tatsumi, S.; Strengbom, J.; Cugnovs, M.; Kouki, J.

10.1101/2020.02.24.956631 — ecology — Posted on 2020-02-25

667 In silico chemical profiling and identification of neuromodulators from Curcuma amada targeting Acetylcholinesterase

Ali, M. C.; Munni, Y. A.; Das, R.; Sultana, M.; Akter, N.; Rahman, M.; Uddin, M. N.; Das, K.; Hossen, M.; Hannan, M. A.; Dash, R.

10.1101/2020.02.22.960732 — bioinformatics — Posted on 2020-02-25

668 A Novel Index for Predicting Health Status Using Species-level Gut Microbiome Profiling

Gupta, V. K.; Kim, M.; Bakshi, U.; Cunningham, K. Y.; Davis, J. M.; Lazaridis, K. N.; Nelson, H.; Chia, N.; Sung, J.

10.1101/2020.02.24.962100 — bioinformatics — Posted on 2020-02-25

669 How Sensitive are EEG Results to Preprocessing Methods: A Benchmarking Study

Robbins, K.; Touryan, J. O.; Mullen, T.; Kothe, C.; Bigdely-Shamlo, N.

10.1101/2020.01.20.913327 — neuroscience — Posted on 2020-02-25

670 Coevolution of retroviruses with SERINCs following whole-genome duplication divergence

Ramdas, P.; Bhardwaj, V.; Singh, A.; Vijay, N.; Chande, A.

10.1101/2020.02.24.962506 — microbiology — Posted on 2020-02-25

671 Building a high-quality reference genome assembly for the eastern Mediterranean Sea invasive sprinter Lagocephalus sceleratus (Tetraodontiformes, Tetraodontidae)

Danis, T.; Tsakogiannis, A.; Kristoffersen, J. B.; Golani, D.; Tsaparis, D.; Kasapidis, P.; Kotoulas, G.; Magoulas, A.; Tsigenopoulos, C. S.; Manousaki, T.

10.1101/2020.02.17.952580 — genomics — Posted on 2020-02-25

672 IFN-{lambda}4 increases the risk of gastrointestinal infections and malaria in Malian children

Prokunina-Olsson, L.; Morrison, R. L.; Obajemu, A.; Mahamar, A.; Kim, S.; Attaher, O.; Florez-Vargas, O.; Sidibe, Y.; Onabajo, O. O.; Hutchinson, A. A.; Manning, M.; Kwan, J.; Brand, N.; Dicko, A.; Fried, M.; Albert, P. S.; Mbulaiteye, S. M.; Duffy, P. E.

10.1101/2020.02.24.962688 — genetics — Posted on 2020-02-25

673 Sequencing depth and genotype quality: Accuracy and breeding operation considerations for genomic selection applications in autopolyploid crops

Gemenet, D. C.; Lindqvist-Kreuze, H.; Olukolu, B. A.; De Boeck, B.; da Silva Pereira, G.; Mollinari, M.; Zeng, Z.-B.; Yencho, G. C.; Campos, H.

10.1101/2020.02.23.961383 — genetics — Posted on 2020-02-25

674 Immunoinformatic design of multi epitopes peptide-based universal cancer vaccine using matrix metalloproteinase-9 protein as a target

abdelmoneim, a. h.; Mustafa, M. I.; Abdelmageed, M. I.; Murshed, N. S.; Dawoud, E. d.; Ahmed, E. M.; Kamal eldein, R. M.; Elfadol, N. M.; Mohamed sati, A. O.; Makhawi, A. M.

10.1101/2020.02.16.951319 — immunology — Posted on 2020-02-25

675 Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and -deficient cells

Michelena, J.; Pellegrino, S.; Spegg, V.; Altmeyer, M.

10.1101/2020.02.24.947168 — cell biology — Posted on 2020-02-25

676 Reducing shock imminence eliminates poor avoidance in rats

Laughlin, L. C.; Moloney, D. M.; Samels, S. B.; Sears, R. M.; Cain, C. K.

10.1101/2020.01.30.927152 — animal behavior and cognition — Posted on 2020-02-25

677 Variation of human neural stem cells generating organizer states in vitro before committing to cortical excitatory or inhibitory neuronal fates

Micali, N.; Kim, S.-K.; Diaz-Bustamante, M.; Stein-O'Brien, G.; Seo, S.; Shin, J.-H.; Rash, B. G.; Ma, S.; Wang, Y.; Arellano, J.; Olivares, N. A.; Maynard, K. R.; Fertig, E. J.; Cross, A. J.; Burli, R.; Brandon, N. J.; Weinberger, D. R.; Chenoweth, J. G.; Hoeppner, D. J.; Sestan, N.; Rakic, P.; Colantuoni, C.; McKay, R. D.

10.1101/577544 — neuroscience — Posted on 2020-02-25

678 DREAM: A Toolbox to Decode Rhythms of the Brain System

Gong, Z.-Q.; Gao, P.; Jiang, C.; Xing, X.-X.; Dong, H.-M.; White, T. H.; Castellanos, F. X.; Li, H.-F.; Zuo, X.-N.

10.1101/2020.01.29.926204 — neuroscience — Posted on 2020-02-25

679 3D Epigenomic Characterization Reveals Insights Into Gene Regulation and Lineage Specification During Corticogenesis

Song, M.; Pebworth, M.-P.; Yang, X.; Abnousi, A.; Fan, C.; Wen, J.; Rosen, J.; Choudhary, M.; Cui, X.; Jones, I.; Bergenholtz, S.; Eze, U.; Juric, I.; Li, B.; Maliskova, L.; Liu, W.; Pollen, A.; Li, Y.; Wang, T.; Hu, M.; Kriegstein, A.; Shen, Y.

10.1101/2020.02.24.963652 — genomics — Posted on 2020-02-25

680 Control of tissue development by cell cycle dependent transcriptional filtering

Abou Chakra, M.; Isserlin, R.; Tran, T.; Bader, G. D.

10.1101/2020.02.25.964650 — developmental biology — Posted on 2020-02-25

681 A gradient from long-term memory to novel cognition: graded transitions through default mode and executive cortex

Wang, X.; Margulies, D. S.; Smallwood, J.; Jefferies, E.

10.1101/2020.01.16.908327 — neuroscience — Posted on 2020-02-25

682 Multivariate Analyses of Codon Usage of SARS-CoV-2 and other betacoronaviruses

Gu, H.; Chu, D. K. W.; Peiris, J. S. M.; Poon, L. L. M.

10.1101/2020.02.15.950568 — evolutionary biology — Posted on 2020-02-25

683 Anti-inflammatory role of curcumin in Lipopolysaccharide treated A549 cells at global proteome level and on mycobacterial infection

Singh, S.; Arya, R.; Bargaje, R. R.; Das, M. K.; Akram, S.; Faruquee, H. M.; Behera, R. K.; Nanda, R.; Agrawal, A.

10.1101/721100 — biochemistry — Posted on 2020-02-25

684 Identifying inhibitors of epithelial-mesenchymal plasticity using a network topology based approach

Hari, K.; Sabuwala, B.; Subramani, B. V.; La Porta, C.; Zapperi, S.; Font-Clos, F.; Jolly, M. K.

10.1101/854307 — systems biology — Posted on 2020-02-25

685 Genome-scale Model Constrained by Proteomics Reveals Metabolic Changes in Streptomyces coelicolor M1152 Compared to M145

Sulheim, S.; Kumelj, T.; van Dissel, D.; Salehzadeh-Yazdi, A.; Du, C.; van Wezel, G. P.; Nieselt, K.; Almaas, E.; Wentzel, A.; Kerkhoven, E. J.

10.1101/796722 — systems biology — Posted on 2020-02-25

686 What influences treatment response in animal models of non-alcoholic fatty liver disease? A meta-analysis with meta-regression.

Hunter, H.; de Gracia Hahn, D.; Duret, A.; Im, Y. R.; Cheah, Q.; Dong, J.; Fairey, M.; Hjalmarsson, C.; Li, A.; Lim, H. K.; McKeown, L.; Mitrofan, C.-G.; Rao, R.; Utukuri, M.; Rowe, I. A.; Mann, J. P.

10.1101/2019.12.31.887919 — physiology — Posted on 2020-02-25

687 Pollutants in Hong Kong Soil: As, Cd, Cr, Cu, Hg, Pb and Zn

Chung, M. K.; Cheung, K. C.; Wong, M. H.

10.1101/2020.02.16.951558 — pharmacology and toxicology — Posted on 2020-02-25

688 Pollutants in Hong Kong Soils: Organochlorine Pesticides and Polychlorinated Biphenyls

Chung, M. K.; Hu, R.; Cheung, K. C.; Wong, M. H.

10.1101/2020.02.16.951541 — pharmacology and toxicology — Posted on 2020-02-25

689 Effects of dopamine agonist treatment on resting-state network connectivity in Parkinson's disease

Cole, D. M.; Mohammadi, B.; Milenkova, M.; Kollewe, K.; Schrader, C.; Samii, A.; Dengler, R.; Muente, T. F.; Beckmann, C. F.

10.1101/2020.01.31.928853 — neuroscience — Posted on 2020-02-25

690 Aging and the encoding of changes in events: The role of neural activity pattern reinstatement

Stawarczyk, D.; Wahlheim, C.; Etzel, J. A.; Snyder, A. Z.; Zacks, J. M.

10.1101/809806 — neuroscience — Posted on 2020-02-25

691 Different forms of fear extinction are supported by distinct cortical substrates

Lay, B.; Pitaru, A. A.; Boulianne, N.; Esber, G. R.; Iordanova, M. D.

10.1101/2020.01.27.921221 — neuroscience — Posted on 2020-02-25

692 Fronto-temporal coupling dynamics during spontaneous activity and auditory processing

Garcia-Rosales, F.; Lopez-Jury, L.; Gonzalez-Palomares, E.; Cabral-Calderin, Y.; Hechavarria, J. C.

10.1101/2019.12.23.886770 — neuroscience — Posted on 2020-02-25

693 The neural link between subjective value and decision entropy

Bobadilla-Suarez, S.; Guest, O.; Love, B. C.

10.1101/2020.02.18.954362 — neuroscience — Posted on 2020-02-25

694 Reward modulates behaviour and neural responses in motor cortex during action observation

Cretu, A. L.; Lehner, R.; Polania, R.; Wenderoth, N.

10.1101/868083 — neuroscience — Posted on 2020-02-25

695 Genetic association of FMRP targets with psychiatric disorders

Clifton, N. E.; Rees, E.; Holmans, P.; Pardinas, A. F.; Harwood, J. C.; Di Florio, A.; Kirov, G.; Walters, J. T.; O'Donovan, M. C.; Owen, M. J.; Hall, J.; Pocklington, A.

10.1101/2020.02.21.952226 — neuroscience — Posted on 2020-02-25

696 High-throughput cellular-resolution synaptic connectivity mapping in vivo with concurrent two-photon optogenetics and volumetric Ca2+ imaging

McRaven, C.; Tanese, D.; Zhang, L.; Yang, C.-T.; Ahrens, M. B.; Emiliani, V.; Koyama, M.

10.1101/2020.02.21.959650 — neuroscience — Posted on 2020-02-25

697 T cells limit accumulation of aggregate pathology following intrastriatal injection of α-synuclein fibrils

George, S.; Tyson, T.; Rey, N. L.; Sheridan, R.; Peelaerts, W.; Becker, K.; Schulz, E.; Meyerdirk, L.; Burmeister, A.; Steiner, J.; Escobar, M. L.; Ma, J.; Brundin, L.; Brundin, P.

10.1101/2020.02.20.956599 — neuroscience — Posted on 2020-02-25

698 A modular neural network model of grasp movement generation

Michaels, J. A.; Schaffelhofer, S.; Agudelo-Toro, A.; Scherberger, H.

10.1101/742189 — neuroscience — Posted on 2020-02-25

699 Specialized DNA structures act as genomic beacons for integration by evolutionarily diverse retroviruses.

Kohio, H. P.; Ajoge, H. O.; Coleman, M. D.; Ndashimye, E.; Gibson, R. M.; Arts, E. J.; Barr, S. D.

10.1101/2020.02.23.959932 — molecular biology — Posted on 2020-02-25

700 Cell cycle-associated expression patterns predict gene function in mycobacteria

Bandekar, A. C.; Subedi, S.; Ioerger, T. R.; Sassetti, C. M.

10.1101/2020.02.10.942268 — microbiology — Posted on 2020-02-25

701 A framework for effective application of machine learning to microbiome-based classification problems

Topcuoglu, B. D.; Lesniak, N. A.; Ruffin, M. T.; Wiens, J.; Schloss, P. D.

10.1101/816090 — microbiology — Posted on 2020-02-25

702 Fate mapping quantifies the dynamics of B cell development and activation throughout life

Verheijen, M.; Rane, S.; Pearson, C.; Yates, A. J.; Seddon, B.

10.1101/871624 — immunology — Posted on 2020-02-25

703 Complement C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodelling.

Wood, A. J.; Vassallo, A. M.; Ruchard-Sparagano, M.-H.; Scott, J.; Zinnato, C.; Gonzalez-Tejedo, C.; Kishore, K.; D'Santos, C.; Simpson, A. J.; Menon, D.; Summers, C.; Chilvers, E. R.; Okkenhaug, K.; Conway Morris, A.

10.1101/2020.01.17.907618 — immunology — Posted on 2020-02-25

704 LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium

Zwiggelaar, R.; Lindholm, H.; Fosslie, M.; Pedersen, M. T.; Ohta, Y.; Diez-Sanchez, A.; Martin-Alonso, M.; Ostrop, J.; Matano, M.; Parmar, N.; Kvaloy, E.; Spanjers, R.; Nazmi, K.; Rye, M. B.; Drablos, F.; Arrowsmith, C.; Dahl, J. A.; Jensen, K. B.; Sato, T.; Oudhoff, M. J.

10.1101/2020.02.20.958363 — developmental biology — Posted on 2020-02-25

705 Quasi-periodic migration of single cells on short microlanes

Zhou, F.; Schaffer, S. A.; Schreiber, C.; Segerer, F. J.; Goychuk, A.; Frey, E.; Raedler, J. O.

10.1101/809939 — biophysics — Posted on 2020-02-25

706 The helix bundle domain of primase RepB' is required for dinucleotide formation and extension

Banchenko, S.; Weise, C.; Lanka, E.; Saenger, W.; Geibel, S.

10.1101/2020.02.20.955914 — biochemistry — Posted on 2020-02-25

707 Arabidopsis LTR retrotransposons and their regulation by epigenetically activated small RNA

Lee, S. C.; Ernst, E.; Berube, B.; Borges, F.; Parent, J.-S.; Ledon, P.; Schorn, A.; Martienssen, R. A.

10.1101/2020.01.24.919167 — genomics — Posted on 2020-02-25

708 Challenging a preconception: Optoacoustic spectrum differs from the absorption spectrum of proteins and dyes for molecular imaging

Fuenzalida Werner, J. P.; Huang, Y.; Mishra, K.; Chmyrov, A.; Ntziachristos, V.; Stiel, A. C.

10.1101/2020.02.01.930230 — biophysics — Posted on 2020-02-25

709 The Drosophila HP1 family is associated with active gene expression across chromatin contexts

Schoelz, J.; Feng, J.; Riddle, N.

10.1101/2020.02.24.958538 — genomics — Posted on 2020-02-25

710 No more business as usual: agile and effective responses to emerging pathogen threats require open data and open analytics

Galaxy and HyPhy developments teams, ; Nekrutenko, A.; Kosakovsky Pond, S. L.

10.1101/2020.02.21.959973 — genomics — Posted on 2020-02-25

711 Changes in subcellular structures and states of Pumilio1 regulate the translation of target Mad2 and Cyclin B1 mRNAs

Kotani, T.; Takei, N.; Takada, Y.; Kawamura, S.; Saitoh, A.; Bormann, J.; Yuen, W. S.; Carroll, J.

10.1101/2020.02.25.964668 — cell biology — Posted on 2020-02-25

712 An in vitro vesicle formation assay to analyze protein sorting in the secretory transport pathway

Huang, Y.; Yin, H.; Tang, X.; Wu, Q.; Wang, M.; Poljak, K.; Li, B.; Liu, Y.; Wu, Z.; Jiang, L.; Miller, E. A.; Yao, Z.-P.; Guo, Y.

10.1101/2020.02.12.945162 — cell biology — Posted on 2020-02-25

713 Coupling of conformational switches in calcium sensor unraveled with local Markov models and transfer entropy

Hempel, T.; Plattner, N.; Noe, F.

10.1101/2020.02.25.964353 — biophysics — Posted on 2020-02-25

714 Comparative genomic analyses and a novel linkage map for cisco (Coregonus artedi) provide insights into chromosomal evolution and rediploidization across salmonids

Blumstein, D. M.; Campbell, M. A.; Hale, M. C.; Sutherland, B. J. G.; McKinney, G. J.; Stott, W.; Larson, W. A.

10.1101/834937 — genomics — Posted on 2020-02-25

715 Mutation bias can shape adaptation in large asexual populations experiencing clonal interference

Gomez, K.; Bertram, J.; Masel, J.

10.1101/2020.02.17.953265 — evolutionary biology — Posted on 2020-02-25

716 Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts

Juhlen, R.; Martinelli, V.; Vinci, C.; Breckpot, J.; Fahrenkrog, B.

10.1101/756734 — cell biology — Posted on 2020-02-25

717 Interaction with phospho-eIF4E commits S6 Kinase 1 for mTORC2 and PHLPP1 mediated activation.

Majeed, S. T.; Batool, A.; Majeed, R.; Bhat, N. N.; Andrabi, K. I.

10.1101/2020.02.15.944892 — cell biology — Posted on 2020-02-25

718 Proliferation and Survival of T-cell Acute Lymphoblastic Leukaemia Depends on mTOR-regulated Glutamine Uptake and EAAT1-dependent Conversion of Glutamine to Aspartate and Nucleotides

Stanulovic, V. S.; Reed, M. A. C.; Patani, H.; Potluri, S.; Georgiadou, E.; Roberts, J.; Sarkar, S.; Pratt, G. E.; Jones, A. M.; Gunther, U. L.; Ludwig, C.; Hoogenkamp, M.

10.1101/2020.02.08.939694 — cancer biology — Posted on 2020-02-25

719 Modelling FtsZ nucleation, hydrolysis and treadmilling activity with Monte Carlo methods

Corbin, L.; Erickson, H. P.

10.1101/2020.02.25.965095 — biophysics — Posted on 2020-02-25

720 LMSM: a modular approach for identifying lncRNA related miRNA sponge modules in breast cancer

Zhang, J.; Xu, T.; Liu, L.; Zhang, W.; Zhao, C.; Li, S.; Li, J.; Rao, N.; Le, T.

10.1101/841502 — bioinformatics — Posted on 2020-02-25

721 A Bayesian nonparametric approach to super-resolution single-molecule localization

Gabitto, M. I.; Marie-Nelly, H.; Pakman, A.; Pataki, A.; Darzacq, X.; Jordan, M.

10.1101/2020.02.15.950873 — bioinformatics — Posted on 2020-02-25

722 Glycopeptide variable window SWATH for improved Data Independent Acquisition glycoprotein analysis

Zhou, C.; Schulz, B. L.

10.1101/739615 — biochemistry — Posted on 2020-02-25

723 Acidification of Cytoplasmic pH in Escherichia coli Provides a Strategy to Cope with Stress and Facilitates Development of Antibiotic Resistance

Reyes-Fernandez, E. Z.; Schuldiner, S.

10.1101/2020.02.24.963876 — biochemistry — Posted on 2020-02-25

724 Cooperative policing behavior regulates reproductive division of labor in a termite

Sun, Q.; Hampton, J.; Haynes, K.; Merchant, A.; Zhou, X.

10.1101/2020.02.04.934315 — animal behavior and cognition — Posted on 2020-02-25

725 Urethral luminal epithelia are castration-insensitive progenitors of the proximal prostate

Joseph, D. B.; Henry, G. H.; Malewska, A.; Iqbal, N.; Ruetten, H. M.; Turco, A. E.; Abler, L. L.; Sandhu, S. K.; Cadena, M. T.; Malladi, V. S.; Reese, J. C.; Mauck, R. J.; Gahan, J. C.; Hutchinson, R. C.; Roehrborn, C. G.; Baker, L. A.; Vezina, C. M.; Strand, D. W.

10.1101/2020.02.19.937615 — cell biology — Posted on 2020-02-25

726 Stability of Two-quartet G-quadruplexes and Their Dimers in Atomistic Simulations

Islam, B.; Stadlbauer, P.; Vorlickova, M.; Mergny, J.-L.; Otyepka, M.; Sponer, J.

10.1101/820852 — biophysics — Posted on 2020-02-25

727 Conserved small nucleotidic elements at the origin of concerted piRNA biogenesis from genes and lncRNAs

Jensen, S.; Brasset, E.; Parey, E.; Roest Crollius, H.; Sharakhov, I. V.; Vaury, C.

10.1101/2020.02.05.936112 — bioinformatics — Posted on 2020-02-25

728 Audio-visual combination of syllables involves time-sensitive dynamics following from fusion failure

Bouton, S.; Delgado Saa, J. F.; Olasagasti, I.; Giraud, A.-L.

10.1101/771634 — neuroscience — Posted on 2020-02-25

729 Shared Neural Representations of Cognitive Conflict and Negative Affect in the Medial Frontal Cortex

Vermeylen, L.; Wisniewski, D.; Gonzalez-Garcia, C.; Hoofs, V.; Notebaert, W.; Braem, S.

10.1101/824839 — neuroscience — Posted on 2020-02-25

730 Decisions bias future choices by modifying hippocampal associative memories

Luettgau, L.; Tempelmann, C.; Kaiser, L. F.; Jocham, G.

10.1101/802462 — neuroscience — Posted on 2020-02-25

731 The influence of maternal malnutrition on folate and inositol production and transport in the placenta and gut - a mechanism for fetal growth restriction and fetal disorders?

Palladino, E.; Van Mieghem, T.; Connor, K. L.

10.1101/767012 — developmental biology — Posted on 2020-02-25

732 Zebrafish Kit ligands cooperate with erythropoietin to promote erythroid cell expansion

Oltova, J.; Svoboda, O.; Machonova, O.; Svatonova, P.; Traver, D.; Kolar, M.; Bartunek, P.

10.1101/2020.02.03.931634 — developmental biology — Posted on 2020-02-25

733 Knockdown of CSNK2β suppresses MDA-MB231 cells growth, induces apoptosis, inhibits migration and invasion

Pokharel, Y. R.; Karna, S. K. L.; Lone, B. A.; Shahi, N.

10.1101/2020.02.24.963769 — cancer biology — Posted on 2020-02-25

734 Brain network dynamics correlate with personality traits

Kabbara, A.; Paban, V.; Modolo, J.; Weill, A.; Hassan, M.

10.1101/702266 — bioinformatics — Posted on 2020-02-25

735 Population structure of Apodemus flavicollis and comparison to Apodemus sylvaticus in northern Poland based on RAD-seq

Martin Cerezo, M. L.; Kucka, M.; Zub, K.; Chan, Y. F.; Bryk, J.

10.1101/625848 — genomics — Posted on 2020-02-25

736 Controlling evolutionary dynamics to optimize microbial bioremediation

Shibasaki, S.; Mitri, S.

10.1101/705749 — evolutionary biology — Posted on 2020-02-25

737 Postpartum fluoxetine increased maternal hippocampal IL-1β and decreased plasma tryptophan: clues for efficacy

Qiu, W.; Duarte-Guterman, P.; Eid, R. S.; Go, K.; Lamers, Y.; Galea, L.

10.1101/2020.02.22.960021 — neuroscience — Posted on 2020-02-25

738 Toward a unified connectomic target for deep brain stimulation in obsessive-compulsive disorder

Li, N.; Baldermann, J. C.; Kibleur, A.; Treu, S.; Akram, H.; Elias, G. J. B.; Boutet, A.; Lozano, A. M.; Zrinzo, L.; Joyce, E.; Chabardes, S.; Visser-Vandewalle, V.; Polosan, M.; Kuhn, J.; Kühn, A. A.; Horn, A.

10.1101/608786 — neuroscience — Posted on 2020-02-25

739 An evaluation of pool-sequencing transcriptome-based exon capture for population genomics in non-model species

Deleury, E.; Guillemaud, T.; Blin, A.; Lombaert, E.

10.1101/583534 — genomics — Posted on 2020-02-25

740 Predicting evolution using frequency-dependent selection in bacterial populations

Azarian, T.; Martinez, P. P. P.; Arnold, B. J.; Grant, L. R.; Corander, J.; Fraser, C.; Croucher, N.; Hammitt, L.; Reed, R.; Santosham, M.; Weatherholtz, R. R.; Bentley, S. D.; O'Brien, K. L.; Lipsitch, M.; Hanage, W. P.

10.1101/420315 — evolutionary biology — Posted on 2020-02-25

741 Same law, diverging practice: comparative analysis of Endangered Species Act consultations by two federal agencies

Evansen, M.; Li, Y.-W.; Malcom, J.

10.1101/165647 — ecology — Posted on 2020-02-25

742 Histone acetyltransferase inhibition rescues differentiation of emerin-null myogenic progenitors

Bossone, K. A.; Ellis, J. A.; Holaska, J. M.

10.1101/437343 — cell biology — Posted on 2020-02-25

743 Elucidating the Influence of Linker Histone Variants on Chromatosome Dynamics and Energetics

Woods, D. C.; Weresczczynski, J.

10.1101/660076 — biophysics — Posted on 2020-02-25

744 Drivers of grass endophyte communities in prairies of the Pacific Northwest, USA

Bailes, G.; Thomas, D.; Bridgham, S. D.; Roy, B. A.

10.1101/2020.02.23.953489 — ecology — Posted on 2020-02-25

745 Emergence of a novel interaction between brown bear and cicada due to anthropogenic habitat modification

Tomita, K.; Hiura, T.

10.1101/2020.02.22.960583 — ecology — Posted on 2020-02-25

746 Pair consensus decoding improves accuracy of neural network basecallers for nanopore sequencing

Silvestre-Ryan, J.; Holmes, I.

10.1101/2020.02.25.956771 — bioinformatics — Posted on 2020-02-25

747 Control of E-S Potentiation at two different sites in the dendro-somatic axis

Clark, J. K.; Madison, D. V.

10.1101/2020.02.21.960138 — neuroscience — Posted on 2020-02-25

748 Latent Plasticity of Effector-like Exhausted CD8 T cells contributes to memory responses

Raju, S.; Xia, Y.; Daniel, B.; Yost, K. E.; Bradshaw, E.; Tonc, E.; Verbaro, D. J.; Satpathy, A. T.; Egawa, T.

10.1101/2020.02.22.960278 — immunology — Posted on 2020-02-25

749 Loss of pseudouridine synthases in the RluA family causes hypersensitive nociception in Drosophila

Song, W.; Tracey, W. D.

10.1101/831917 — genetics — Posted on 2020-02-25

750 Functional insights from biophysical study of TREM2 interactions with ApoE and Aβ1-42

Kober, D. L.; Stuchell-Brereton, M. D.; Kluender, C. E.; Dean, H. B.; Strickland, M. R.; Steinberg, D. F.; Nelson, S. S.; Baban, B.; Holtzman, D. M.; Frieden, C.; Alexander-Brett, J. M.; Roberson, E. D.; Song, Y.; Brett, T. J.

10.1101/2020.02.24.963264 — biophysics — Posted on 2020-02-25

751 Complete reconstruction of the unbinding pathway of an anticancer drug by conventional unbiased molecular dynamics simulation

Sohraby, F.; Javaheri Moghadam, M.; Aliyar, M.; Aryapour, H.

10.1101/2020.02.23.961474 — bioinformatics — Posted on 2020-02-25

752 The metabolite receptor SUCNR1 in oxidative stress-induced age-related macular degeneration

Louer, E. M. M.; Deen, P. M. T.; Den Hollander, A. I.

10.1101/2020.02.24.962779 — biochemistry — Posted on 2020-02-25

753 Identification of radiation responsive proteins from Spleen and Intestine tissue of mice using Mass Spectrometry approach.

Hussain, M. S.; Ahmed, F.; Kumar, R.; Saini, A. K.; Shubham, S.; Shasthry, S. M.; Salman, M. T.

10.1101/2020.02.24.962647 — biochemistry — Posted on 2020-02-25

754 Inflammatory state of lymphatic vessels and miRNA profiles associated with relapse in ovarian cancer patients

Johnson, S. C.; Chakraborty, S.; Drosou, A.; Cunnea, P.; Tzovara, D.; Nixon, K.; Zawieja, D. C.; Muthuchamy, M.; Fotopoulou, C.; Moore, J. E.

10.1101/2020.02.24.962480 — cancer biology — Posted on 2020-02-25

755 Dpp and Hedgehog promote the Glial response to neuronal damage in the developing Drosophila Visual system

Velarde, S. B.; Quevedo, A.; Estella, C.; Baonza, A.

10.1101/2020.02.24.960625 — neuroscience — Posted on 2020-02-25

756 Visualizing ultrastructural details of placental tissue with super-resolution structured illumination microscopy

Villedgas-Hernandez, L. E.; Nystad, M.; Strohl, F.; Basnet, P.; Acharya, G.; Ahluwalia, B. S.

10.1101/2020.02.22.960559 — pathology — Posted on 2020-02-25

757 A pan-cancer analysis of the frequency of DNA alterations across cell cycle activity levels

Lundberg, A.; Lindström, L. S.; Parker, J. S.; Löverli, E.; Perou, C. M.; Bergh, J.; Tobin, N. P.

10.1101/2020.02.24.962571 — genomics — Posted on 2020-02-25

758 Ovarian Cancer Risk Variants are Enriched in Histotype-Specific Enhancers that Disrupt Transcription Factor Binding Sites

Jones, M. R.; Peng, P.-C.; Coetzee, S. G.; Tyrer, J.; Reyes, A. L. P.; Corona de la Fuente, R. I.; Davis, B. D.; Chen, S.; Dezem, F.; Seo, J.-H.; Ovarian Cancer Association Consortium, ; Berman, B. P.; Freedman, M. L.; Plummer, J. T.; Lawrenson, K.; Pharoah, P.; Hazelett, D. J.; Gayther, S. A.

10.1101/2020.02.21.960468 — genetics — Posted on 2020-02-25

759 Polycystin-2 (TRPP2) Regulates Primary Cilium Length in LLC-PK1 Renal Epithelial Cells

Perez, P. L.; Scarinci, N.; Cantiello, H. F.; Cantero, M. d. R.

10.1101/2020.02.24.962860 — cell biology — Posted on 2020-02-25

760 CD117/c-kit Represents a Prostate Cancer Stem-Like Subpopulation Driving Progression, Migration, and TKI Resistance

Harris, K.; Shi, L.; Foster, B.; Mobley, M.; Elliott, P.; Song, C.; Watabe, K.; Langefeld, C.; Kerr, B.

10.1101/256107 — cancer biology — Posted on 2020-02-25

761 New insights into Trypanosoma cruzi evolution and genotyping based on system-wide protein expression profiles (PhyloQuant)

Ngao Mule, S.; Guillherme da Costa Martins, A.; Rosa-Fernandes, L.; Santos de Oliveira, G.; Rodrigues, C. M.; Quina, D.; Rosein, G. E.; Teixeira, M. M. G.; Palmisano, G.

10.1101/2020.02.21.959767 — evolutionary biology — Posted on 2020-02-25

762 Dynamics as a cause for the nanoscale organization of the genome

Barth, R.; Fourel, G.; SHABAN, H.

10.1101/2020.02.24.963470 — biophysics — Posted on 2020-02-25

763 Single-Cell Mass Cytometry on Peripheral Blood Identifies Immune Cell Subsets Associated with Primary Biliary Cholangitis

Jang, J. S.; Juran, B. D.; Cunningham, K. Y.; Gupta, V. K.; Son, Y.; Yang, J. D.; Ali, A. H.; Enninga, E. A.; Sung, J.; Lazaridis, K.

10.1101/2020.02.24.962043 — bioinformatics — Posted on 2020-02-25

764 Phytochemical Screening and Antimicrobial Activity of Ziziphus spina-christi Stem Barks

Makhawi, A. M.; Mustafa, M. I.; Uagoub, H. A.

10.1101/2020.02.24.963157 — biochemistry — Posted on 2020-02-25

765 Bagging Improves Reproducibility of Functional Parcellation of the Human Brain

Nikolaidis, A.; Solon Heinsfeld, A.; Xu, T.; Bellec, P.; Vogelstein, J.; Milham, M.

10.1101/343392 — neuroscience — Posted on 2020-02-25

766 Effect of choline-phosphate cytidylyltransferase gene (pcyt-1) expression on departure of pine wood nematode, Bursaphelenchus xylophilus (Nematoda: Aphelenchoididae), from Monochamus alternatus (Coleoptera:Cerambycidae)

Wang, Y.; Chen, F.

10.1101/2020.02.22.943852 — zoology — Posted on 2020-02-25

767 Light microscopy based approach for mapping connectivity with molecular specificity

Shen, F. Y.; Harrington, M. M.; Walker, L. A.; Cheng, H. P. J.; Boyden, E. S.; Cai, D.

10.1101/2020.02.24.963538 — neuroscience — Posted on 2020-02-25

768 A CRISPR/Cas9-Based Approach For Editing Immortalised Human Myoblasts To Model Duchenne Muscular Dystrophy In Vitro

Soblechero-Martin, P.; Albiasu-Arteta, E.; Anton-Martinez, A.; Garcia-Jimenez, I.; Gonzalez-Iglesias, G.; Larranaga-Aiestaran, I.; Lopez-Martinez, A.; Poyatos-Garcia, J.; Ruiz-Del-Yerro, E.; Gonzalez, F.; Arechavala-Gomeza, V.

10.1101/2020.02.24.962316 — neuroscience — Posted on 2020-02-25

769 Inhibitory parvalbumin basket cells are selectively impaired during hippocampal sharp wave ripples in a mouse model of familial Alzheimer's disease

Caccavano, A.; Bozzelli, P. L.; Forcelli, P. A.; Pak, D. T. S.; Wu, J.-Y.; Conant, K.; Vicini, S.

10.1101/2020.02.21.959676 — neuroscience — Posted on 2020-02-25

770 Anopheles stephensi as an emerging malaria vector in the Horn of Africa with high susceptibility to Ethiopian Plasmodium vivax and Plasmodium falciparum isolates

Amenu, T. A.; Teka, H.; Esayas, E.; Messenger, L. A.; Chali, W.; Meerstein-Kessel, L.; Walker, T.; Behaksra, S. W.; Lanke, K.; Heutink, R.; Jeffries, C. L.; Mekonnen, D. A.; Hailemeskel, E.; Tafesse, T.; Gashaw, A.; Tsegaye, T.; Emiru, T.; Simon, K.; Bogale, E. A.; Yohannes, G.; Kedir, S.; Shumie, G.; Sabir, S. A.; Mumba, P.; Dengela, D.; Kolaczinski, J. H.; Wilson, A.; Churcher, T. S.; Chibsa, S.; Murphy, M.; Balkew, M.; Irish, S.; Drakeley, C.; Gadisa, E.; Bousema, T.; Tadesse, F. G.

10.1101/2020.02.22.961284 — microbiology — Posted on 2020-02-25

771 Characterization of nuclear mitochondrial insertions in the whole genomes of primates

Dayama, G.; Zhou, W.; Mills, R.

10.1101/2020.02.24.963504 — genomics — Posted on 2020-02-25

772 A quantitative framework reveals the ecological drivers of grassland soil microbial community assembly in response to warming

Ning, D.; Yuan, M.; Wu, L.; Zhang, Y.; Guo, X.; Zhou, X.; Yang, Y.; Arkin, A. P.; Firestone, M. K.; Zhou, J.

10.1101/2020.02.22.960872 — ecology — Posted on 2020-02-25

773 Models of the ventral stream that categorize and visualize images

Christensen, E.; Zylberberg, J.

10.1101/2020.02.21.958488 — neuroscience — Posted on 2020-02-25

774 A genetically encoded GRAB sensor for measuring serotonin dynamics in vivo

Wan, J.; Peng, W.; Li, X.; Qian, T.; Song, K.; Zeng, J.; Deng, F.; Hao, S.; Feng, J.; Zhang, P.; Zhang, Y.; Zou, J.; Pan, S.; Zhu, J. J.; Jing, M.; Xu, M.; Li, Y.

10.1101/2020.02.24.962282 — neuroscience — Posted on 2020-02-25

775 Dynamic Changes in Fecal Bacterial Microbiota of Dairy Cattle across the Production Line

Zhao, L.; Li, X.; Atwill, E. R.; Aly, S.; Williams, D. R.; Rossitto, P.; Su, Z.

10.1101/2020.02.21.960500 — microbiology — Posted on 2020-02-25

776 Convergent losses of TLR5 suggest altered extracellular flagellin detection in four mammalian lineages

Sharma, V.; Walther, F.; Hecker, N.; Stuckas, H.; Hiller, M.

10.1101/2020.02.23.962035 — genomics — Posted on 2020-02-25

777 Altered hematopoietic system and self-tolerance in Bardet-Biedl Syndrome

Tsyklauri, O.; Niederlova, V.; Forsythe, E.; Drobek, A.; Prasai, A.; Sparks, K.; Trachtulec, Z.; Beales, P. L.; Huranova, M.; Stepanek, O.

10.1101/2020.02.24.962886 — genetics — Posted on 2020-02-25

778 A zebrafish functional genomics model to investigate the role of human A20 variants in vivo

Cultrone, D.; Zammit, N.; Self, E.; Walters, S.; Warren, J.; Bailey, J.; Han, J. Z.; Croucher, D. R.; Kikuchi, K.; Bogdanovic, O.; Chtanova, T.; Hesselson, D.; Grey, S. T.

10.1101/2020.02.23.961763 — genetics — Posted on 2020-02-25

779 ERECTA family signaling constrains CLAVATA3 and WUSCHEL to the center of the shoot apical meristem.

Zhang, L.; DeGennaro, D.; Lin, G.; Chai, J.; Shpak, E. D.

10.1101/2020.02.24.962787 — developmental biology — Posted on 2020-02-25

780 RNF40-dependent epigenetic regulation of actin cytoskeletal dynamics is required for HER2-driven mammary tumorigenesis

Wegwitz, F.; Prokakis, E.; Pejkovska, A.; Kosinsky, R. L.; Glatzel, M.; Pantel, K.; Wikman, H.; Johnsen, S. A.

10.1101/2020.02.24.962902 — cancer biology — Posted on 2020-02-25

781 Tumour gene expression signature in primary melanoma predicts long-term outcomes: A prospective multicentre study

Garg, M.; Courturier, D.-L.; Nsengimana, J.; Fonseca, N. A.; Wongchenko, M.; Yan, Y.; Lauss, M.; Jönsson, G. B.; Newton-Bishop, J.; Parkinson, C.; Middleton, M. R.; Bishop, T.; Corrie, P.; Adams, D. J.; Brazma, A.; Rabbie, R.

10.1101/2020.02.24.961771 — bioinformatics — Posted on 2020-02-25

782 AmpliCI: A High-resolution Model-Based Approach for Denoising Illumina Amplicon Data

Peng, X.; Dorman, K. S.

10.1101/2020.02.23.961227 — bioinformatics — Posted on 2020-02-25

783 Discovery of biased orientations of human regulatory motifs affecting transcription of genes and including known insulators

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2020-02-25

784 Imaging cell lineage with a synthetic digital recording system

Chow, K.-H. K.; Budde, M. W.; Granados, A. A.; Cabrera, M.; Yoon, S.; Cho, S.; Huang, T.-h.; Koulena, N.; Frieda, K. L.; Cai, L.; Lois, C.; Elowitz, M. B.

10.1101/2020.02.21.958678 — synthetic biology — Posted on 2020-02-25

785 Vicarious reward unblocks associative learning about novel cues in male rats

van Gurp, S.; Hoog, J.; Kalenscher, T.; van Wingerden, M.

10.1101/612697 — animal behavior and cognition — Posted on 2020-02-25

786 Prostaglandin receptor EP2 is a novel molecular target for high-risk neuroblastoma

Hou, R.; Yu, Y.; Nguyen, D. T.; Sluter, M. N.; Li, L.; Yang, J.; Jiang, J.

10.1101/2020.02.24.963108 — pharmacology and toxicology — Posted on 2020-02-25

787 SimpylCellCounter: An Automated Solution for Quantifying Cells in Brain Tissue

Bal, A.; Maureira, F.; Arguello, A. A.

10.1101/2020.02.22.960948 — neuroscience — Posted on 2020-02-25

788 Alterations of specific inhibitory circuits of the prefrontal cortex underlie abnormal network activity in a mouse model of Down syndrome

Zorrilla de San Martin, J.; Donato, C.; Peixoto, J.; Aguirre, A.; Choudhary, V.; De Stasi, A. M.; Lourenco, J.; Potier, M.-C.; Bacci, A.

10.1101/2020.02.24.963041 — neuroscience — Posted on 2020-02-25

789 A self-initiated cue-reward learning procedure for neural recording in rodents

Reverte, I.; Volz, S.; Alhazmi, F. H.; Kang, M.; Kaufman, K.; Chan, S.; Jou, C.; Iordanova, M. D.; Esber, G. R.

10.1101/2020.02.24.963447 — neuroscience — Posted on 2020-02-25

790 Toward a unified connectomic target for deep brain stimulation in obsessive-compulsive disorder

10.1101/608786 — neuroscience — Posted on 2020-02-25

791 Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus that are Necessary for Synapse Function

Gokhale, A.; Lee, C. E.; Zlatic, S. A.; Freeman, A. A.; Shearing, N.; Hartwig, C.; Ogunbona, O.; Bassell, J. L.; Wynne, M. E.; Werner, E.; Xu, C.; Wen, Z.; Seyfried, N.; Bearden, C. E.; Glausier, J.; Lewis, D. A.; Faundez, V.

10.1101/2020.02.22.960971 — neuroscience — Posted on 2020-02-25

792 Specialized DNA structures act as genomic beacons for integration by evolutionarily diverse retroviruses.

Kohio, H. P.; Ajoge, H. O.; Coleman, M. D.; Ndashimye, E.; Gibson, R. M.; Arts, E. J.; Barr, S. D.

10.1101/2020.02.23.959932 — molecular biology — Posted on 2020-02-25

793 Lanthanide transport, storage, and beyond: gene products and processes contributing to lanthanide and methanol metabolism in Methylorubrum extorquens AM1

Roszczenko-Jasinska, P.; Vu, H. N.; Subuyuj, G. A.; Crisostomo, R. V.; Ayala, E. M.; Cai, J.; Lien, N. F.; Clippard, E. J.; Ngo, R. T.; Raghuraman, C.; Yarza, F.; Hoeber, C. A.; Martinez-Gomez, N. C.; Skovran, E.

10.1101/647677 — microbiology — Posted on 2020-02-25

794 Multidimensional Analysis of Bronchoalveolar Lavage Cytokines and Mast Cell Proteases Reveals Interferon-γ as a Key Biomarker in Equine Asthma Syndrome

Woodrow, J. S.; Hines, M.; Sommardahl, C.; Flatland, B.; Davis, K.; Wang, Z.; Sheats, M. K.; Lo, Y.; Lennon, E. M.

10.1101/2020.02.24.956573 — immunology — Posted on 2020-02-25

795 HiCSR: a Hi-C super-resolution framework for producing highly realistic contact maps

Dimmick, M. C.; Lee, L. J.; Frey, B. J.

10.1101/2020.02.24.961714 — genomics — Posted on 2020-02-25

796 Single-molecule sequencing of long DNA molecules allows high contiguity de novo genome assembly for the fungus fly, Sciara coprophila

Urban, J. M.; Foulk, M. S.; Bliss, J. E.; Coleman, C. M.; Lu, N.; Mazloom, R.; Brown, S. J.; Spradling, A. C.; Gerbi, S. A.

10.1101/2020.02.24.963009 — genomics — Posted on 2020-02-25

797 Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs

Hwang, L.-D.; Tubbs, J. D.; Luong, J.; Moen, G.-H.; Sham, P. C.; Cuellar Partida, G.; Evans, D. M.

10.1101/2020.02.21.959114 — genetics — Posted on 2020-02-25

798 The strength and form of natural selection on transcript abundance in the wild

Ahmad, F.; Debes, P. V.; Nousiainen, I.; Kahar, S.; Pukk, L.; Gross, R.; Ozerov, M.; Vasemägi, A.

10.1101/2020.02.24.948828 — evolutionary biology — Posted on 2020-02-25

799 Creating outbred and inbred populations of haplodiploid mites to measure adaptive responses in the lab

Godinho, D. P.; Cruz, M. A.; de la Masseliere, M. C.; Teodoro-Paulo, J.; Eira, C.; Fragata, I.; Rodrigues, L. R.; Zele, F.; Magalhaes, S.

10.1101/2020.02.22.960682 — evolutionary biology — Posted on 2020-02-25

800 Divergence, gene flow and the origin of leapfrog geographic distributions: The history of color pattern variation in Phyllobates poison-dart frogs

Marquez, R.; Linderoth, T. P.; Mejía-Vargas, D.; Nielsen, R.; Kronforst, M. R.; Amezquita, A.

10.1101/2020.02.21.960005 — evolutionary biology — Posted on 2020-02-25

801 Community-wide seed dispersal distances peak at low levels of specialisation in size-structured networks

Sorensen, M. C.; Schleuning, M.; Donoso, I.; Neuschulz, E. L.; Mueller, T.

10.1101/2020.02.23.958454 — ecology — Posted on 2020-02-25

802 Lower Soil Carbon Loss Due to Persistent Microbial Adaptation to Climate Warming

Guo, X.; Gao, Q.; Yuan, M.; Wang, G.; Zhou, X.; Feng, J.; Shi, Z.; Hale, L.; Wu, L.; Zhou, A.; Tian, R.; Liu, F.; Wu, B.; Chen, L.; Gyo Jung, C.; Niu, S.; Li, D.; Xu, X.; Jiang, L.; Escalas, A.; Wu, L.; He, Z.; Van Nostrand, J.; Ning, D.; Liu, X.; Yang, Y.; Schuur, E.; Konstantinidis, K. T.; Cole, J. R.; Penton, C. R.; Luo, Y.; Tiedje, J.; Zhou, J.

10.1101/2020.02.23.961300 — ecology — Posted on 2020-02-25

803 Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments

Pir Cakmak, F.; Choi, S.; Meyer, M. O.; Bevilacqua, P. C.; Keating, C. D.

10.1101/2020.02.23.961920 — biophysics — Posted on 2020-02-25

804 Post-copulatory behavior of olive baboons (Papio anubis) infected by Treponema pallidum

Paciencia, F. M.; Chuma, I. S.; Lipende, I. F.; Knauf, S.; Zinner, D.

10.1101/2020.02.23.961326 — animal behavior and cognition — Posted on 2020-02-25

805 The Hox transcription factor Ubx ensures somatic myogenesis by suppressing the mesodermal master regulator Twist

Domsch, K.; Schroeder, J.; Janeschik, M.; Schaub, C.; Lohmann, I.

10.1101/2020.02.24.963231 — developmental biology — Posted on 2020-02-25

806 Plastid gene expression is required for singlet oxygen-induced chloroplast degradation and cell death

Alamdari, K.; Fisher, K. E.; Sinson, A. B.; Chory, J.; Woodson, J. D.

10.1101/2020.02.24.961144 — plant biology — Posted on 2020-02-25

807 Copper nanoparticle application enhances plant growth and grain yield in maize under drought stress conditions

Ha, C. V.; Nguyen, D. V.; Nguyen, H. M.; Le, N. T.; Nguyen, K. H.; Le, H. M.; Nguyen, A. T.; Dinh, N. T. T.; Hoang, S. A.

10.1101/2020.02.24.963132 — plant biology — Posted on 2020-02-25

808 Ultrasound Mediated Delivery of Quantum Dots from a Capsule Endoscope to the Gastrointestinal Wall

Stewart, F.; Cummins, G.; Turcanu, M. V.; Cox, B. F.; Prescott, A. R.; Clutton, E.; Newton, I. P.; Desmulliez, M. P. Y.; Thanou, M.; Mulvana, H.; Cochran, S.; Nathke, I.

10.1101/2020.02.24.963066 — bioengineering — Posted on 2020-02-25

809 Antinociceptive modulation by the adhesion-GPCR CIRL promotes mechanosensory signal discrimination

Dannhäuser, S.; Lux, T. J.; Hu, C.; Selcho, M.; Tsung-Chieh Chen, J.; Ehmann, N.; Sachidanandan, D.; Pawlak, M.; Langenhan, T.; Soba, P.; Rittner, H.; Kittel, R. J.

10.1101/2020.02.24.963439 — physiology — Posted on 2020-02-25

810 14-3-3ζ regulates lipolysis by influencing adipocyte maturity

Oppong, A.; Diallo, K.; Robillard Frayne, I.; Des Rosiers, C.; Lim, G.

10.1101/2020.02.24.962662 — physiology — Posted on 2020-02-25

811 The Bayesian Superorganism: collective probability estimation in swarm systems

Hunt, E. R.; Franks, N. R.; Baddeley, R. J.

10.1101/468942 — animal behavior and cognition — Posted on 2020-02-25

812 The Bayesian Superorganism: collective probability estimation in swarm systems

Hunt, E. R.; Franks, N. R.; Baddeley, R. J.

10.1101/468942 — animal behavior and cognition — Posted on 2020-02-25

813 The influence of peptide context on signalling and trafficking of glucagon-like peptide-1 receptor biased agonists

Fang, Z.; Chen, S.; Pickford, P.; Broichhagen, J.; Hodson, D.; Correa, I. R.; Kumar, S.; Gorlitz, F.; Dunsby, C.; French, P.; Rutter, G. A.; Tan, T.; Bloom, S. R.; Tomas, A.; Jones, B.

10.1101/2020.02.24.961524 — pharmacology and toxicology — Posted on 2020-02-25

814 Projections of non-invasive human recordings into state space show unfolding of spontaneous and over-trained choice

Takagi, Y.; Hunt, L. T.; Woolrich, M. W.; Behrens, T. E. J.; Klein-Flugge, M.

10.1101/2020.02.24.962290 — neuroscience — Posted on 2020-02-25

815 Brainrender. A python based software for visualisation of neuroanatomical and morphological data.

Claudi, F.; Tyson, A. L.; Branco, T.

10.1101/2020.02.23.961748 — neuroscience — Posted on 2020-02-25

816 Red-light (670 nm) therapy reduces mechanical sensitivity and neuronal cell death, and alters glial responses following spinal cord injury in rats

Hu, D.; Moalem-Taylor, G.; Potas, J. R.

10.1101/2020.02.22.960641 — neuroscience — Posted on 2020-02-25

817 Infra-slow modulation of fast beta/gamma oscillations in the mouse visual system.

Orlowska-Feuer, P.; Allen, A. E.; Brown, T. M.; Szkudlarek, H. J.; Lucas, R. J.; Storchi, R.

10.1101/2020.02.24.963124 — neuroscience — Posted on 2020-02-25

818 Adult mouse retina explants: an ex vivo window to explore central nervous system diseases

Schaeffer, J.; Tardy, C.; Albert, F.; Belin, S.; Nawabi, H.

10.1101/2020.02.22.960609 — neuroscience — Posted on 2020-02-25

819 Untargeted Metabolomics Shows Alterations in Homocysteine, Lipids, and Fatty Acids Predicting Memory Decline in Healthy Middle-Aged Individuals

Hajjar, I.; Cai, Q.; Yu, T.; Jones, D. P.

10.1101/2020.02.23.949537 — neuroscience — Posted on 2020-02-25

820 TRIBE editing reveals specific mRNA targets of eIF4E-BP in Drosophila and in mammals

Jin, H.; Na, D.; Rahman, R.; Xu, W.; Fieldsend, A.; Song, W.; Liu, S.; Li, C.; Rosbash, M.

10.1101/2020.02.24.962852 — molecular biology — Posted on 2020-02-25

821 miR169 and PmRGL2 synergistically regulate NF-Y complex to active dormancy release in Japanese apricot (Prunus mume Sieb. et Zucc.)

Gao, J.; Ni, X.; Li, H.; Hayat, F.; Shi, T.; Gao, Z.

10.1101/2020.02.24.963355 — molecular biology — Posted on 2020-02-25

822 A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts

Midgett, C. R.; Swindell, R. A.; Pellegrini, M.; Kull, F. J.

10.1101/2020.02.24.963330 — microbiology — Posted on 2020-02-25

823 DNA methylation epigenetically regulates gene expression in Burkholderia cenocepacia

Vandenbussche, I.; Sass, A.; Pinto-Carbo, M.; Mannweiler, O.; Eberl, L.; Coenye, T.

10.1101/2020.02.21.960518 — microbiology — Posted on 2020-02-25

824 ANME-1 archaea drive methane accumulation and removal in estuarine sediments

Kevorkian, R.; Callahan, S.; Winstead, R.; Lloyd, K. G.

10.1101/2020.02.24.963215 — microbiology — Posted on 2020-02-25

825 Staphylococcal DNA repair confers tolerance of the bactericidal activity of both neutrophils and antibiotics

Ha, K. P.; Clarke, R. S.; Brittan, J. L.; Rowley, J. E.; Mavridou, D.; Clarke, T. B.; Nobbs, A. H.; Edwards, A. M.

10.1101/2020.02.23.961458 — microbiology — Posted on 2020-02-25

826 Clinical and genomic epidemiology of carbapenem-non-susceptible Citrobacter spp. at a tertiary healthcare center over two decades

Babiker, A.; Evans, D. R.; Griffith, M. P.; McElheny, C. L.; Hassan, M.; Clarke, L. G.; Mettus, R. T.; Harrison, L. H.; Doi, Y.; Shields, R. K.; Van Tyne, D.

10.1101/2020.02.21.959742 — microbiology — Posted on 2020-02-25

827 Poxvirus-encoded TNF receptor homolog dampens inflammation and protects the host from uncontrolled lung pathology and death during respiratory infection

Al Rumaih, Z.; Tuazon Kels, M. J.; Ng, E.; Pandey, P.; Pontejo, S. M.; Alejo, A.; Alcami, A.; Chaudhri, G.; Karupiah, G.

10.1101/2020.02.24.963520 — immunology — Posted on 2020-02-25

828 The Drosophila HP1 family is associated with active gene expression across chromatin contexts

Schoelz, J.; Riddle, N.; Feng, J.

10.1101/2020.02.24.958538 — genomics — Posted on 2020-02-25

829 In silico integration of thousands of epigenetic datasets into 707 cell type regulatory annotations improves the trans-ethnic portability of polygenic risk scores

Amariuta, T.; Ishigaki, K.; Sugishita, H.; Ohta, T.; Matsuda, K.; Murakami, Y.; Price, A. L.; Kawakami, E.; Terao, C.; Raychaudhuri, S.

10.1101/2020.02.21.959510 — genetics — Posted on 2020-02-25

830 Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments

Greenway, R.; Barts, N.; Henpita, C.; Brown, A. P.; Arias-Rodriguez, L.; Rodriguez Pena, C. M.; Arndt, S.; Lau, G. Y.; Murphy, M. P.; Wu, L.; Lin, D.; Shaw, J. H.; Kelley, J. L.; Tobler, M.

10.1101/2020.02.24.959916 — evolutionary biology — Posted on 2020-02-25

831 Barriers to coexistence limit the poleward range of a globally-distributed plant

Armitage, D. W.; Jones, S. E.

10.1101/2020.02.24.946574 — ecology — Posted on 2020-02-25

832 Using changes in host demographic rates to reveal the effects of infection with hidden variable models

Ferguson, J. M.; Gonzalez-Gonzalez, A.; Kaiser, J. A.; Winzer, S. M.; Anast, J. M.; Ridenhour, B.; Miura, T. A.; Parent, C. E.

10.1101/2020.02.22.961128 — ecology — Posted on 2020-02-25

833 An agent-based model of the Foraging Ascomycete Hypothesis

Thomas, D. C.; Vandegrift, R.; Roy, B.

10.1101/197707 — ecology — Posted on 2020-02-25

834 Non-coding germline GATA3 variants alter chromatin topology and contribute to pathogenesis of acute lymphoblastic leukemia

Yang, H.; Zhang, H.; Luan, Y.; Liu, T.; Roberts, K. G.; Qian, M.-x.; Zhang, B.; Yang, W.; Perez-Andreu, V.; Xu, J.; Iyyanki, S.; Kuang, D.; Reshmi, S. C.; Gastier-Foster, J.; Smith, C.; Pui, C.-H.; Evans, W. E.; Hunger, S. P.; Platanias, L. C.; Relling, M. V.; Mullighan, C. G.; Loh, M. L.; Yue, F.; Yang, J. J.

10.1101/2020.02.23.961672 — cancer biology — Posted on 2020-02-25

835 R/UAStools::plotshpcreate: Create Multi-Polygon Shapefiles for Extraction of Research Plot Scale Agriculture Remote Sensing Data.

Anderson, S. L.; Murray, S. C.

10.1101/2020.02.21.960203 — bioinformatics — Posted on 2020-02-25

836 A Pumpless Microfluidic Neonatal Lung Assist Device for Support of Preterm Neonates in Respiratory Distress

Dabaghi, M.; Rochow, N.; Saraei, N.; Fusch, G.; Monkman, S.; Da, K.; Shahin Shamsabadi, A.; L. Brash, J.; Predescu, D.; Delaney, K.; Fusch, C.; Selvaganapathy, P. R.

10.1101/2020.02.22.961102 — bioengineering — Posted on 2020-02-25

837 Quantitative LCMS for ceramides/dihydroceramides: pregnancy baseline biomarkers and potential metabolic messengers

Huang, Q.; Hao, S.; Yao, X.; You, J.; Li, X.; Lai, D.; Han, C.; Schilling, J.; Hwa, K. Y.; Thyparambil, S.; Whitin, J.; Cohen, H. J.; Chubb, H. J.; Ceresnak, S. R.; McElhinney, D. B.; Shaw, G. M.; Stevenson, D. K.; Sylvester, K. G.; Ling, X. B.

10.1101/2020.02.24.963462 — biochemistry — Posted on 2020-02-25

838 A neutrophil-driven inflammatory signature characterizes the blood cell transcriptome fingerprints of Psoriasis and Kawasaki Disease

Rawat, A.; Rinchai, D.; Toufiq, M.; Marr, A.; Kino, T.; Garand, M.; Karim, M. Y.; Sastry, S.; Chouchane, A.; Chaussabel, D.

10.1101/2020.02.24.962621 — immunology — Posted on 2020-02-25

839 Ecological memory preserves phage resistance mechanisms in bacteria

Skanata, A.; Kussell, E.

10.1101/2020.02.23.961862 — evolutionary biology — Posted on 2020-02-25

840 Transcriptome analysis of somatic cell populations in the Drosophila testis links metabolism and stemness

Hof-Michel, S.; Boekel, C.

10.1101/2020.02.24.962639 — developmental biology — Posted on 2020-02-25

841 Cellular heterogeneity-adjusted clonal methylation (CHALM) provides better prediction of gene expression

Xu, J.; Shi, J.; Cui, X.; Cui, Y.; Li, J.; Goel, A.; Chen, X.; Su, J.; Issa, J.-P.; Li, W.

10.1101/2020.02.23.961813 — bioinformatics — Posted on 2020-02-25

842 Structure and conformational cycle of a bacteriophage-encoded chaperonin

Hayer-Hartl, M.; Bracher, A.; Paul, S. S.; Wang, H.; Wischnewski, N.; Hartl, F. U.

10.1101/2020.02.24.962803 — biochemistry — Posted on 2020-02-25

843 A Rad51-Independent P{-}ath{-}way Promotes Single-Strand Template Repair in Gene Editing

Gallagher, D.; Pham, N. T.; Tsai, A.; Janto, A.; Choi, J.; Ira, G.; Haber, J. E.

10.1101/2020.02.24.962423 — genetics — Posted on 2020-02-24

844 Kinetics characterization of ASXL1/2-mediated allosteric regulation of BAP1 deubiquitinase

Peng, H.; Cassel, J.; McCracken, D.; Prokop, J. W.; Collop, P. R.; Polo, A.; Joshi, S.; Mandell, J. P.; Ayyanathan, K.; Hinds, D.; Malkowicz, S. B.; Harbour, J. W.; Bowcock, A. M.; Salvino, J.; Kennedy, E. J.; Testa, J. R.; Rauscher, F. J.

10.1101/2020.02.24.962464 — cancer biology — Posted on 2020-02-24

845 Basal leakage in oscillation: coupled transcriptional and translational control using feed-forward loops

Hsu, C.-P.; Joanito, I.; Sanders, C.-C.; Chu, J.-W.; Wu, S.-H.

10.1101/2020.02.24.962415 — systems biology — Posted on 2020-02-24

846 Intra-abdominal resection of the umbilical vein and urachus of bovine fetuses using videolaparoscopy and celiotomy: surgical time and feasibility (cadaveric study)

Monteiro, F. D. O.; Gurgel, H. J.; de Sousa, S. S.; Barroso, J. P. M.; Vasconcelos, G. P. B.; dos Santos, D. L.; Araujo, L. H. V.; de Sousa, L. A.; dos Santos, G. M. A.; Rossy, K. d. C.; da Silva, V. S.; Fernandes, C. d. E. S.; Guilherme, B. d. C.; Miranda, H. F.; Silva, C. R. G.; Albuquerque, R. d. S.; Borges, L. P. B.; de Araujo, G. F.; Teixeira, P. P. M.

10.1101/2020.02.24.962431 — pathology — Posted on 2020-02-24

847 Coevolution of retroviruses with SERINCs following whole-genome duplication divergence

Ramdas, P.; Bhardwaj, V.; Singh, A.; Vijay, N.; Chande, A.

10.1101/2020.02.24.962506 — microbiology — Posted on 2020-02-24

848 Correlation of pathogenic factors with antimicrobial resistance of clinical Proteus mirabilis strains

Filipiak, A.; Chrapek, M.; Literacka, E.; Wawszczak, M.; Głuszek, S.; Majchrzak, M.; Wrobel, G.; Gniadkowski, M.; Adamus-Bialek, W.

10.1101/2020.02.24.962514 — microbiology — Posted on 2020-02-24

849 Marmoset monkeys (Callithrix jacchus) develop eosinophilic airway inflammation after house dust mite exposure

Dahlmann, F.; Curths, C.; Wichmann, J.; Jimenez Delgado, S.; Twisterling, E.; Kap, Y. S.; van Driel, N.; t Hart, B. A.; Knauf, Y.; Becker, T.; Dunker, S.; Windt, H.; Bleyer, M.; Kaup, F.-J.; Sewald, K.; Braun, A.; Knauf, S.

10.1101/2020.02.24.962498 — immunology — Posted on 2020-02-24

850 Ecological stoichiometric characteristics of Carbon (C), Nitrogen (N) and Phosphorus (P) in leaf, root, stem, and soil in four wetland plants communities in Shengjin Lake, China,

Dibar, D. T.; Zhang, K.; Ye, X.; Zhou, Z.; Yuan, S.; Zhang, J.

10.1101/2020.02.24.962456 — ecology — Posted on 2020-02-24

851 shRNA Glut-1 inhibits cell viability, apoptosis and migration of laryngeal carcinoma HEp-2 cells through regulating Beclin-1-mediated autophagy

Wang, W.-D.; Zhu, J.-L.; Zhou, S.-H.; Fan, J.; Bao, Y.-Y.

10.1101/2020.02.24.962449 — cancer biology — Posted on 2020-02-24

852 Wald's martingale and the Moran process

Monk, T. E.; van Schaik, A.

10.1101/2020.02.24.962407 — evolutionary biology — Posted on 2020-02-24

853 Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins and insights into coronavirus evolution

Yu, J.; Qiao, S.; Guo, R.; Wang, X.

10.1101/2020.02.23.961912 — biochemistry — Posted on 2020-02-24

854 The Intergenic Small Non-Coding RNA ittA is Required for Optimal Infectivity and Tissue Tropism in Borrelia burgdorferi

Medina-Perez, D.; Wager, B.; Troy, E.; Gao, L.; Norris, S.; Lin, T.; Hu, L.; Hyde, J.; Lybecker, M.; Skare, J. T.

10.1101/2020.02.24.962522 — microbiology — Posted on 2020-02-24

855 A CURE for physiological characterization of bacterioplankton in liquid culture

Lanclos, V. C.; Coelho, J. T.; Hyer, A.; Brooks, M. M.; Savoie, E. R.; Kosiba, S.; Thrash, C.

10.1101/2020.02.21.959940 — scientific communication and education — Posted on 2020-02-24

856 Ketogenic Diet Prevents Heart Failure from Defective Mitochondrial Pyruvate Metabolism

McCommis, K. S.; Kovacs, A.; Weinheimer, C. J.; Shew, T. M.; Koves, T. R.; Ilkayeva, O. R.; Kamm, D. R.; Pyles, K. D.; King, M. T.; Veech, R. L.; DeBosch, B. J.; Muoio, D. M.; Gross, R. W.; Finck, B. N.

10.1101/2020.02.21.959635 — physiology — Posted on 2020-02-24

857 Hyper-connectivity of the striatum related to restricted and repetitive behaviors' severity in children with ASD

Dupong, I.; Di Martino, A.

10.1101/2020.02.21.957993 — neuroscience — Posted on 2020-02-24

858 Targeting lateral inhibition to improve vision following macular degeneration

Rizzi, M.; Powell, K.; Robinson, M. R.; Matsuki, T.; Hoke, J.; Maswood, R. N.; Georgiadis, A.; Georgiou, M.; Jones, P. R.; Ripamonti, C.; Michaelides, M.; Rubin, G. S.; Smith, A. J.; Ali, R. R.

10.1101/2020.02.21.953828 — neuroscience — Posted on 2020-02-24

859 Sleep Deprivation alters the influence of biological sex on active-phase sleep behavior

Nichols, I.; Vincent, S. M.; Hesse, S.; Ehlen, J. C.; Brager, A.; Paul, K. N.

10.1101/2020.02.21.958231 — neuroscience — Posted on 2020-02-24

860 Reduced expression of PD-L1 and IDO1 characterises early response to antimonial therapy in cutaneous leishmaniasis patients.

Dey, N. S.; Senarathna, S.; Somaratne, V.; Madarasinghe, N.; Seneviratne, B.; Reis, L. C.; Moulik, S.; Walrad, P.; Chatterjee, M.; Goto, H.; Wickremasinghe, R.; Lagos, D.; Kaye, P. M.; Ranasinghe, S.

10.1101/2020.02.21.959528 — immunology — Posted on 2020-02-24

861 Loss of graded enemy recognition in a Whitehead population allopatric with brood parasitic Long-tailed Cuckoos

Lawson, S. L.; Leuschner, N.; Gill, B. J.; Enos, J. K.; Hauber, M. E.

10.1101/2020.02.21.958017 — animal behavior and cognition — Posted on 2020-02-24

862 Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces

Ghate, K.; Mutalik, S. P.; Sthanam, L. K.; Sen, S.; Ghose, A.

10.1101/2020.02.21.959759 — neuroscience — Posted on 2020-02-24

863 Private-public mappings in human prefrontal cortex

Bang, D.; Ershadmanesh, S.; Nili, H.; Fleming, S. M.

10.1101/2020.02.21.954305 — neuroscience — Posted on 2020-02-24

864 Slow Wave Oscillation reveals the discrete segregation of dorsal striatum

Alegre-Cortes, J.; Saez, M.; Montanari, R.; Reig, R.

10.1101/2020.02.21.959692 — neuroscience — Posted on 2020-02-24

865 Transcriptional control of parallel-acting pathways that remove discrete presynaptic proteins in remodeling neurons

Miller, D. M.; Fleming-Miller, T. W.; Cuentas-Condori, A.; Manning, L.; Palumbos, S.; Richmond, J. E.

10.1101/2020.02.21.959700 — neuroscience — Posted on 2020-02-24

866 Gene expression has more power for predicting in vitro cancer cell vulnerabilities than genomics

Dempster, J. M.; Krill-Burger, J.; Warren, A.; McFarland, J.; Golub, T.; Tsherniak, A.

10.1101/2020.02.21.959627 — cancer biology — Posted on 2020-02-24

867 Prognostic significance of SOCS1 and SOCS3 tumor suppressors in hepatocellular carcinoma and its correlation to key oncogenic signaling pathways

Khan, M. G. M.; Ghosh, A.; Variya, B.; Santharam, M. A.; Ihsan, A. U.; Ramanathan, S.; Ilangumaran, S.

10.1101/2020.02.21.958801 — cancer biology — Posted on 2020-02-24

868 DISPERSE: A trait database to assess the dispersal potential of aquatic macroinvertebrates

Sarremejane, R.; Cid Puey, N.; Datry, T.; Stubbington, R.; Alp, M.; Canedo-Arguelles, M.; Cordero-Rivera, A.; Csabai, Z.; Gutierrez Canovas, C.; Heino, J.; Forcellini, M.; Millan, A.; Paillex, A.; Paril, P.; Polasek, M.; Tierno de Figueroa, J. M.; Usseglio-Polatera, P.; Zamora-Munoz, C.; Bonada, N.

10.1101/2020.02.21.953737 — ecology — Posted on 2020-02-24

869 Transcriptome analysis of browning human neck area adipocytes reveals strong influence by the FTO intronic SNP variant in addition to tissue and PPARγ specific regulation

Toth, B. B.; Arianti, R.; Shaw, A.; Vamos, A.; Vereb, Z.; Poliska, S.; Gyory, F.; Bacso, Z.; Fesus, L.; Kristof, E.

10.1101/2020.02.21.959593 — cell biology — Posted on 2020-02-24

870 Simple post-translational circadian clock models from selective sequestration

Byrne, M. O.

10.1101/2020.02.21.958827 — systems biology — Posted on 2020-02-24

871 Polar mutagenesis of bacterial transcriptional units using Cas12a

Cisneros, D. A.; Uhlin, B. E.; Graffeuil, A.

10.1101/2020.02.21.959866 — microbiology — Posted on 2020-02-24

872 Single cell sequencing of the small and AT-skewed genome of malaria parasites

Liu, S.; Huckaby, A. C.; Brown, A. C.; Moore, C. C.; Burbulis, I. E.; McConnell, M. J.; Guler, J. L.

10.1101/2020.02.21.960039 — genomics — Posted on 2020-02-24

873 Genome-scale metabolic rewiring to achieve predictable titers rates and yield of a non-native product at scale

Banerjee, D.; Eng, T. T.; Lau, A. K.; Wang, B.; Sasaki, Y.; Herbert, R. A.; Chen, Y.; Liu, Y.; Prahl, J.-P.; Singan, V. R.; Tanjore, D.; Petzold, C. J.; Keasling, J. D.; Mukhopadhyay, A.

10.1101/2020.02.21.954792 — bioengineering — Posted on 2020-02-24

874 Network-based Machine Learning Approach for Structural Domain Identification in Proteins

Tiwari, A.; Parekh, N.

10.1101/2020.02.22.960666 — bioinformatics — Posted on 2020-02-24

875 Mapping proteolytic neo-N termini at the surface of living cells

Weeks, A. M.; Byrnes, J. R.; Lui, I.; Wells, J. A.

10.1101/2020.02.23.961904 — biochemistry — Posted on 2020-02-24

876 Sedation modulates fronto-temporal predictive coding circuits and the double surprise acceleration effect

Witon, A.; Shirazibehehsti, A.; Aviles, A.; Adapa, R.; Menon, D.; Chennu, S.; Bekinschtein, T.; Lopez, J. D.; Litvak, V.; Friston, K.; Bowman, H.

10.1101/2020.02.21.959171 — neuroscience — Posted on 2020-02-24

877 Intensity and dose of neuromuscular electrical stimulation influence sensorimotor cortical excitability

Insausti-Delgado, A.; Lopez-Larraz, E.; Omedes, J.; Ramos-Murguialday, A.

10.1101/2020.02.21.957928 — neuroscience — Posted on 2020-02-24

878 An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation

Brandt, M. K.; Kim-Hellmuth, S.; Ziosi, M.; Gokden, A.; Wolman, A.; Lam, N.; Recinos, Y.; Hornung, V. K.; Schumacher, J.; Lappalainen, T.

10.1101/2020.02.21.959734 — genomics — Posted on 2020-02-24

879 A statistical modelling reveals bi-directional chromatin scanning by RAG in the human TCR-α locus

O'Connor, C.; McNamara, D.; Nakagome, S.

10.1101/2020.02.21.959197 — genomics — Posted on 2020-02-24

880 Stocktaking the environmental coverage of a continental ecosystem observation network

Guerin, G. R.; Williams, K. J.; Sparrow, B.; Lowe, A. J.

10.1101/2020.02.20.958769 — ecology — Posted on 2020-02-24

881 The costs of competition: high social status males experience accelerated epigenetic aging in wild baboons

Tung, J.; Anderson, J.; Johnston, R.; Alberts, S.; Archie, E.; Campos, F.

10.1101/2020.02.22.961052 — genomics — Posted on 2020-02-24

882 Genomic profiling of cell lines reveals hidden research bias and caveats

Luo, Y.; Ju, L.; Zhang, Y.; Xiao, Y.; Wang, X.

10.1101/2020.02.23.961516 — cancer biology — Posted on 2020-02-24

883 Machine Learning Based Refined Differential Gene Expression Analysis of Pediatric Sepsis

Abbas, M.; EL-Manzalawy, Y.

10.1101/2020.02.21.959494 — bioinformatics — Posted on 2020-02-24

884 Enzyme Kinetics and Inhibition parameters of Human Leukocyte Glucosylceramidase

Karatas, M.; Dogan, S.; Spahiu, E.; Asic, A.; Besic, L.; Turan, Y.

10.1101/2020.02.23.961599 — biochemistry — Posted on 2020-02-24

885 High-throughput cellular-resolution synaptic connectivity mapping in vivo with concurrent two-photon optogenetics and volumetric Ca2+ imaging

McRaven, C.; Tanese, D.; Zhang, L.; Yang, C.-T.; Ahrens, M. B.; Emiliani, V.; Koyama, M.

10.1101/2020.02.21.959650 — neuroscience — Posted on 2020-02-24

886 An adaptive control scheme for Interleukin-2 therapy

Khailaie, S.; Montaseri, G.; Meyer-Hermann, M.

10.1101/2020.02.21.959221 — immunology — Posted on 2020-02-24

887 Testing the adaptive value of sporulation in budding yeast using experimental evolution

Thomasson, K. M.; Franks, A.; Teotonio, H.; Proulx, S. R.

10.1101/2020.02.23.959684 — evolutionary biology — Posted on 2020-02-24

888 MONET: Multi-omic patient module detection by omic selection

Rappoport, N.; Safra, R.; Shamir, R.

10.1101/2020.02.21.960062 — bioinformatics — Posted on 2020-02-24

889 Molecular basis for regulation of human potassium chloride cotransporters

Chi, X.; Li, X.; Chen, Y.; Zhang, Y.; Su, Q.; Zhou, Q.

10.1101/2020.02.22.960815 — biochemistry — Posted on 2020-02-24

890 Capuchin monkey rituals: an interdisciplinary study of form and function

Perry, S.; Smolla, M.

10.1101/2020.02.21.958223 — animal behavior and cognition — Posted on 2020-02-24

891 Pollutants in Hong Kong Soils: Organochlorine Pesticides and Polychlorinated Biphenyls

Chung, M. K.; Hu, R.; Cheung, K. C.; Wong, M. H.

10.1101/2020.02.16.951541 — pharmacology and toxicology — Posted on 2020-02-24

892 Electrocortical temporal complexity during wakefulness and sleep: an updated account

Gonzalez, J.; Cavelli, M.; Mondino, A.; Pascovich, C.; Castro, S.; Rubido, N.; Torterolo, P.

10.1101/2020.02.20.958462 — neuroscience — Posted on 2020-02-24

893 Temporal and state abstractions for efficient learning, transfer and composition in humans

Xia, L.; Collins, A. G. E.

10.1101/2020.02.20.958587 — neuroscience — Posted on 2020-02-24

894 Neural manifold under plasticity in a goal driven learning behaviour

Feulner, B.; Clopath, C.

10.1101/2020.02.21.959163 — neuroscience — Posted on 2020-02-24

895 Loss of floor plate Netrin-1 impairs midline crossing of corticospinal axons and leads to mirror movements

Pourchet, O.; Morel, M.-P.; Welniarz, Q.; Sarrazin, N.; Marti, F.; Heck, N.; Gallea, C.; Doulazmi, M.; Roig Puiggros, S.; Moreno-Bravo, J. A.; Vidailhet, M.; Trembleau, A.; Faure, P.; Chedotal, A.; Roze, E.; Dusart, I.

10.1101/2020.02.20.958595 — neuroscience — Posted on 2020-02-24

896 DNA-dependent macromolecular condensation drives self-assembly of the meiotic DNA break machinery

Claeys Bouuaert, C.; Pu, S.; Wang, J.; Patel, D. J.; Keeney, S.

10.1101/2020.02.21.960245 — molecular biology — Posted on 2020-02-24

897 Improved Parameterization of Protein-DNA Interactions for Molecular Dynamics Simulations of PCNA Diffusion on DNA

You, S.; Lee, H.; Kim, K.; Yoo, J.

10.1101/2020.02.23.961573 — biophysics — Posted on 2020-02-24

898 Modulation of the Cardiac Sodium Channel Nav1.5 Peak and Late Currents by NAD+ Precursors

Matasic, D.; Yoon, J.-Y.; McLendon, J. M.; Mehdi, H.; Schmidt, M. S.; Greiner, A. M.; Quinones, P.; Morgan, G. M.; Boudreau, R. L.; Irani, K.; Brenner, C.; London, B.

10.1101/2020.02.20.958066 — physiology — Posted on 2020-02-24

899 Elevated blood pressure in high fat diet-exposed low birth weight rat offspring is most likely caused by elevated glucocorticoid levels

Nemoto, T.; Nakakura, T.; Kakinuma, Y.

10.1101/2020.02.21.958884 — physiology — Posted on 2020-02-24

900 Pollutants in Hong Kong Soil: As, Cd, Cr, Cu, Hg, Pb and Zn

Chung, M. K.; Cheung, K. C.; Wong, M. H.

10.1101/2020.02.16.951558 — pharmacology and toxicology — Posted on 2020-02-24

901 A unified neurocomputational bilateral pathway model of spoken language production in healthy participants and recovery in post-stroke aphasia

Chang, Y.-N.; Lambon Ralph, M. A.

10.1101/2020.02.21.959239 — neuroscience — Posted on 2020-02-24

902 Visual psychophysics and limits of visual discrimination performance in freely behaving mice

You, W.-K.; Mysore, S. P.

10.1101/2020.02.20.958652 — neuroscience — Posted on 2020-02-24

903 Control of spontaneous activity patterns by inhibitory signaling in the developing visual cortex

Leighton, A. H.; Houwen, G. J.; Cheyne, J. E.; Maldonado, P. P.; De Winter, F.; Lohmann, C.

10.1101/2020.02.21.959262 — neuroscience — Posted on 2020-02-24

904 Are alpha-band oscillations a default dynamic of the human visual brain, or a product of ongoing visual processes?

Hohaia, W.; Saurels, B. W.; Johnston, A.; Yarrow, K.; Arnold, D. H.

10.1101/2020.02.20.958900 — neuroscience — Posted on 2020-02-24

905 Serum alpha-mannosidase as an additional barrier to eliciting oligomannose-specific HIV-1-neutralizing antibodies

Bruxelle, J.-F.; Kirilenko, T.; Qureshi, Q.; Lu, N.; Trattnig, N.; Kosma, P.; Pantophlet, R.

10.1101/2020.02.24.962233 — immunology — Posted on 2020-02-24

906 Decellularized Plant-Based Scaffolds for Guided Alignment of Myoblast Cells

Campuzano, S.; Mogilever, N. B.; Pelling, A.

10.1101/2020.02.23.958686 — biophysics — Posted on 2020-02-24

907 Thermodynamic and kinetic design principles for protein aggregation inhibitors

Michaels, T. C.; Saric, A.; Meisl, G.; Heller, G. T.; Curk, S.; Arosio, P.; Linse, S.; Dobson, C. M.; Vendruscolo, M.; Knowles, T.

10.1101/2020.02.22.960716 — biophysics — Posted on 2020-02-24

908 Association between proteomic blood biomarkers and DTI/NODDI metrics in adolescent football players

Kawata, K.; Steinfeldt, J. A.; Huibregtse, M. E.; Nowak, M. K.; Macy, J. T.; Shin, A.; Chen, Z.; Ejima, K.; Kercher, K.; Newman, S. D.; Cheng, H.

10.1101/2020.02.20.958694 — neuroscience — Posted on 2020-02-24

909 HIV-1 Vpr antagonizes cGAS sensing by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport

Khan, H.; Sumner, R. P.; Rasaiyaah, J.; Tan, C. P.; Rodriguez-Plata, M. T.; Van Tulleken, C.; Fink, D.; Zuliani-Alvarez, L.; Thorne, L.; Stirling, D.; Towers, G. J.

10.1101/2020.02.22.960757 — microbiology — Posted on 2020-02-24

910 Dissecting the microbiome of a polyketide-producing ascidian across the Anvers Island archipelago, Antarctica

Murray, A. E.; Avalon, N. E.; Bishop, L.; Chain, P. S. G.; Davenport, K. W.; Delage, E.; Dichosa, A. E. K.; Eveillard, D.; Higham, M. L.; Kokkaliari, S.; Lo, C.-C.; Riesenfeld, C. S.; Young, R. M.; Baker, B. J.

10.1101/2020.02.20.958975 — microbiology — Posted on 2020-02-24

911 Control of endoplasmic reticulum membrane biogenesis by regulators of lipid metabolism

Schuck, S.; Bircham, P. W.; Papagiannidis, D.; Luechtenborg, C.; Ruffini, G.; Bruegger, B.

10.1101/2020.02.23.961722 — cell biology — Posted on 2020-02-24

912 T cells limit accumulation of aggregate pathology following intrastriatal injection of α-synuclein fibrils

George, S.; Tyson, T.; Rey, N. L.; Sheridan, R.; Peerlaerts, W.; Becker, K.; Schulz, E.; Meyerdirk, L.; Burmeister, A.; Steiner, J.; Escobar, M. L.; Ma, J.; Brundin, L.; Brundin, P.

10.1101/2020.02.20.956599 — neuroscience — Posted on 2020-02-24

913 Structural and functional characterization of the Spo11 core complex

Claeys Bouuaert, C.; Tischfield, S. E.; Pu, S.; Mimitou, E. P.; Arias-Palomo, E.; Berger, J. M.; Keeney, S.

10.1101/2020.02.21.960211 — molecular biology — Posted on 2020-02-24

914 Identification of a Nonsense-Mediated Decay pathway at the Endoplasmic Reticulum

Longman, D.; Jackson-Jones, K. A.; Maslon, M. M.; Murphy, L. C.; Young, R. S.; Stoddart, J. J.; Taylor, M. S.; Papadopoulos, D. K.; Caceres, J. F.

10.1101/2020.02.24.954453 — molecular biology — Posted on 2020-02-24

915 Genetic association of FMRP targets with psychiatric disorders

Clifton, N. E.; Rees, E. E.; Holmans, P.; Pardinas, A. F.; Harwood, J. C.; Di Florio, A.; Kirov, G.; Walters, J. T.; O'Donovan, M. C.; Owen, M. J.; Hall, J.; Pocklington, A.

10.1101/2020.02.21.952226 — neuroscience — Posted on 2020-02-24

916 Lack of dcf1 leads to neuronal migration delay, axonal swollen and autism-related deficits

Wen, T.; Feng, R.; Chen, Y.; Sun, Y.; Luo, G.; Guo, J.; Liu, Q.; Wu, J.; Ju, X.

10.1101/2020.02.20.958934 — neuroscience — Posted on 2020-02-24

917 Regulated control of gene therapies with a drug induced switch

Monteys, A. M.; Hundley, A. A.; Ranum, P. T.; Tecedor, L.; Muehlmatt, A.; Davidson, B. L.

10.1101/2020.02.21.956664 — molecular biology — Posted on 2020-02-24

918 Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide pools

Sabariegos, R.; Ortega-Prieto, A. M.; Diaz-Martinez, L.; Grande-Perez, A.; Gallego, I.; de Avila, A. I.; Soria, M. E.; Gastaminza, P.; Domingo, E.; Perales, C.; Mas, A.

10.1101/2020.02.21.959536 — microbiology — Posted on 2020-02-24

919 Characterization of exome variants and their metabolic impact in 6,716 American Indians from Southwest US

Kim, H. I.; Gosalia, N.; Ye, B.; Regeneron Genetics Center, ; Köroglu, C.; Hanson, R. L.; Hsueh, W.-C.; Knowler, W. C.; Baier, L. J.; Bogardus, C.; Shuldiner, A. R.; Van Hout, C. V.

10.1101/2020.02.21.938936 — genetics — Posted on 2020-02-24

920 Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions

Seabright, G. E.; Cottrell, C. A.; van Gils, M. J.; D'addabbo, A.; Harvey, D. J.; Beherns, A.-J.; Allen, J. D.; Watanabe, Y.; Maker, A.; Vasiljevic, S.; de Val, N.; Sanders, R. W.; Ward, A. B.; Crispin, M.

10.1101/2020.02.21.959981 — immunology — Posted on 2020-02-23

921 Probing SWATH-MS as a tool for proteome level quantification in a non-model fish

Monroe, A. A.; Zhang, H.; Schunter, C.; Ravasi, T.

10.1101/2020.02.23.946913 — molecular biology — Posted on 2020-02-23

922 Low coverage genomic data resolve the population divergence and gene flow history of an Australian rain forest fig wasp

Cooper, L.; Bunnefeld, L.; Hearn, J.; Cook, J. M.; Lohse, K.; Stone, G. N.

10.1101/2020.02.21.959205 — evolutionary biology — Posted on 2020-02-23

923 Single cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells

Chen, F.; Ding, K.; Priedigkeit, N.; Elangovan, A.; Levine, K. M.; Carleton, N.; Savariau, L.; Atkinson, J. M.; Oesterreich, S.; LEE, A. V.

10.1101/2020.02.21.959023 — cancer biology — Posted on 2020-02-23

924 Combining rational design and continuous evolution on minimalist proteins that target DNA

Inamoto, I.; Sheoran, I.; Popa, S. C.; Hussain, M.; Shin, J. A.

10.1101/2020.02.21.959445 — bioengineering — Posted on 2020-02-23

925 TNF controls a speed-accuracy tradeoff in apoptotic decision to restrict viral spread

Oyler-Yaniv, J.; Oyler-Yaniv, A.; Maltz, E. W.; Wollman, R.

10.1101/2020.02.20.958942 — systems biology — Posted on 2020-02-23

926 Sleep deprivation rapidly upregulates serotonin 2A receptor expression via the immediate early gene Egr3

Zhao, X.; Meyers, K. T.; McBride, A.; Marballi, K. K.; Maple, A. M.; Beck, K. L.; Kang, P.; Palner, M.; Overgaard, A.; Knudsen, G. M.; Gallitano, A. L.

10.1101/634410 — neuroscience — Posted on 2020-02-23

927 Evidence accumulation during perceptual decision-making is sensitive to the dynamics of attentional selection

Rangelov, D.; Mattingley, J. B.

10.1101/537910 — neuroscience — Posted on 2020-02-23

928 Unsupervised experience with temporal continuity of the visual environment is causally involved in the development of V1 complex cells

Matteucci, G.; Zoccolan, D.

10.1101/756668 — neuroscience — Posted on 2020-02-23

929 Land use impacts poison frog chemical defenses through changes in leaf litter ant communities

Moskowitz, N. A.; Dorritie, B.; Fay, T.; Nieves, O. C.; Vidoudez, C.; Cambridge Rindge and Latin 2017 Biology Class, ; Masconomet 2017 Biotechnology Class, ; Fischer, E. K.; Trauger, S. A.; Coloma, L. A.; Donoso, D. A.; O'Connell, L. A.

10.1101/745976 — ecology — Posted on 2020-02-23

930 Mitofusin 2 regulates neutrophil adhesive migration via suppressing Rac activation

Zhou, W.; Hsu, A. Y.; Wang, Y.; Wang, T.; Jeffries, J.; Mohammad, H. T.; Wang, X.; Umulis, D. M.; Seleem, M. N.; Deng, Q.

10.1101/608091 — cell biology — Posted on 2020-02-23

931 Cytoplasmic protein granules organize kinase-mediated RAS signaling

Tulpule, A.; Guan, J.; Neel, D. S.; Lin, Y. P.; Heslin, A.; Allegakoan, H. R.; Perati, S.; Ramirez, A. D.; Shi, X.; Yang, B.; Feng, S.; Makhija, S.; Brown, D.; Huang, B.; Bivona, T. G.

10.1101/704312 — cancer biology — Posted on 2020-02-23

932 Heterosis indices: What do they really measure?

de Vienne, D.; Fievet, J. B.

10.1101/800441 — genetics — Posted on 2020-02-23

933 GeTallele: a method for integrative analysis and visualization of DNA and RNA allele frequencies

Słowinski, P. M.; Li, M.; Restrepo, P.; Alomran, N.; Spurr, L.; Miller, C.; Tsaneva-Atanasova, K.; Horvath, A.

10.1101/491209 — bioinformatics — Posted on 2020-02-23

934 Re-annotation of the Theileria parva genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved pathway in many organisms

Tretina, K.; Pelle, R.; Orvis, J.; Gotia, H. T.; Ifeonu, O. O.; Kumari, P.; Palmateer, N. C.; Iqbal, S. B.; Fry, L.; Nene, V. M.; Daubenberger, C.; Bishop, R. P.; Silva, J. C.

10.1101/749366 — genomics — Posted on 2020-02-23

935 Influenza A viruses serially passaged in different MDCK cell lines exhibit limited sequence variation across their genomes, with the exception of the hemagglutinin gene

Barnard, K. N.; Wasik, B. R.; Alford-Lawrence, B. K.; Hayward, J. J.; Weichert, W.; Voorhees, I. E. H.; Holmes, E. C.; Parrish, C. R.

10.1101/2020.02.20.959015 — microbiology — Posted on 2020-02-23

936 The Pathogenicity of 2019 Novel Coronavirus in hACE2 Transgenic Mice

Bao, L.; Deng, W.; Huang, B.; Gao, H.; Ren, L.; Wei, Q.; Yu, P.; Xu, Y.; Liu, J.; Qi, F.; Qu, Y.; Wang, W.; Li, F.; Lv, Q.; Xue, J.; Gong, S.; Liu, M.; Wang, G.; Wang, S.; Zhao, L.; Liu, P.; Zhao, L.; Ye, F.; Wang, H.; Zhou, W.; Zhu, N.; Zhen, W.; Yu, H.; Zhang, X.; Song, Z.; Guo, L.; Chen, L.; Wang, C.; Wang, Y.; Wang, X.; Xiao, Y.; Sun, Q.; Liu, H.; Zhu, F.; Ma, C.; Yan, L.; Yang, M.; Han, J.; Xu, W.; Tan, W.; Peng, X.; Jin, Q.; Wu, G.; Qin, C.

10.1101/2020.02.07.939389 — microbiology — Posted on 2020-02-23

937 Consumption of a high energy density diet triggers microbiota dysbiosis, hepatic lipidosis, and microglia activation in the nucleus of the solitary tract in rats.

Minaya, D.; Turlej, A.; Joshi, A.; Nagy, T.; Weinstein, N.; Di Lorenzo, P. M.; Hajnal, A.; Czaja, K.

10.1101/2020.02.21.949354 — physiology — Posted on 2020-02-23

938 Status-dependent aging rates in long-lived, social mole-rats are shaped by HPA stress axis

Sahm, A.; Hoffmann, S.; Koch, P.; Henning, Y.; Bens, M.; Groth, M.; Burda, H.; Begall, S.; Ting, S.; Goetz, M.; Van Daele, P.; Staniszewska, M.; Klose, J.; Costa, P. F.; Platzer, M.; Szafranski, K.; Dammann, P.

10.1101/2020.02.22.961011 — genomics — Posted on 2020-02-23

939 Tissue-specific volatile-mediated defense regulation in maize leaves and roots

van Doan, C.; Zuest, T.; Maurer, C.; Zhang, X.; Machado, R. A. R.; Mateo, P.; Ye, M.; Schimmel, B. C. J.; Glauser, G.; Robert, C. A.

10.1101/2020.02.21.959437 — plant biology — Posted on 2020-02-23

940 Endosidin20 is a broad-spectrum cellulose synthesis inhibitor with an herbicidal function

Huang, L.; Zhang, C.

10.1101/2020.02.22.961094 — plant biology — Posted on 2020-02-23

941 Biochar effect - mediated ammonium transporter genes and GDH may be the core of improvement nitrogen assimilation in cotton seedling

Feng, L.; Tang, G.; Xu, W.; Gu, M.; Geng, Z.

10.1101/2020.02.22.960997 — plant biology — Posted on 2020-02-23

942 Mixed Culture of Bacterial Cell for Large Scale DNA Storage

Hao, M.; Qiao, H.; Gao, Y.; Wang, Z.; Qiao, X.; Chen, X.; Qi, H.

10.1101/2020.02.21.960476 — molecular biology — Posted on 2020-02-23

943 Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR

Park, C.; Peng, C.; Rahman, M. J.; Haller, S. L.; Tazi, L.; Brennan, G. J.; Rothenburg, S.

10.1101/2020.02.20.958645 — microbiology — Posted on 2020-02-23

944 Next-generation phylogeography resolves post-glacial colonization patterns in a widespread carnivore, the red fox (Vulpes vulpes), in Europe.

McDevitt, A. D.; Coscia, I.; Browett, S. S.; Ruiz-Gonzalez, A.; Statham, M. J.; Ruczynska, I.; Roberts, L.; Stojak, J.; Frantz, A. C.; Noren, K.; Agren, E.; Learmount, J.; Basto, M.; Fernandes, C.; Stuart, P.; Tosh, D. G.; Sindicic, M.; Andreanszky, T.; Isomursu, M.; Panek, M.; Korolev, A.; Okhlopkov, I. M.; Saveljev, A. P.; Pokorny, B.; Flajsman, K.; Harrison, S. W.; Lobkov, V.; Cirovic, D.; Mullins, J.; Pertoldi, C.; Randi, E.; Sacks, B. N.; Kowalczyk, R.; Wojcik, J. M.

10.1101/2020.02.21.954966 — evolutionary biology — Posted on 2020-02-23

945 Evolution of the standard genetic code

Yarus, M.

10.1101/2020.02.20.958546 — evolutionary biology — Posted on 2020-02-23

946 Unifying the Ambivalent Mechanisms of Protein-Stabilising Osmolytes

Mukherjee, M.; Mondal, J.

10.1101/2020.02.22.960856 — biophysics — Posted on 2020-02-23

947 Prevalence of pathogenic variants in DNA damage response genes in patients undergoing cancer risk assessment and reporting a personal history of early-onset renal cancer

Hartman, T. R.; Demidova, E. V.; Lesh, R. W.; Hoang, L.; Richardson, M. E.; Forman, A.; Kessler, L.; Speare, V.; Golemis, E. A.; Hall, M. J.; Daly, M. B.; Arora, S.

10.1101/2020.02.21.958256 — genetics — Posted on 2020-02-23

948 Directed evolution of Anabaena variabilis phenylalanine ammonia-lyase (PAL) identifies mutants with enhanced activities

Mays, Z. J.; Mohan, K.; Trivedi, V. D.; Chappell, T. C.; Nair, N. U.

10.1101/2020.02.20.933945 — bioengineering — Posted on 2020-02-23

949 Investigation of microbial community interactions between lake Washington methanotrophs using genome-scale metabolic modeling

Islam, M. M.; Le, T.; Daggumati, S. R.; Saha, R.

10.1101/2020.02.21.958074 — systems biology — Posted on 2020-02-23

950 Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei

Quintana Alcala, J. F.; Bueren-Calabuig, J. A.; Zuccotto, F.; de Koning, H.; Horn, D.; Field, M. C.

10.1101/2020.02.22.960963 — microbiology — Posted on 2020-02-23

951 Using whole-genome sequencing and a pentaplex real-time PCR to characterize third-generation cephalosporin-resistant Enterobacteriaceae from Southeast Queensland, Australia

Stewart, A. G.; Price, E. P.; Schabacker, K.; Birikmen, M.; Burnard, D. M.; Harris, P. N.; Choong, K.; Subedi, S.; Sarovich, D. S.

10.1101/2020.02.20.958728 — microbiology — Posted on 2020-02-23

952 Δ-dN/dS: New Criteria to Distinguish among Different Selection Modes in Gene Evolution

gu, x.

10.1101/2020.02.21.960450 — evolutionary biology — Posted on 2020-02-23

953 SMRT sequencing generates the chromosome-scale reference genome of tropical fruit mango, Mangifera indica

Li, W.; Zhu, X.-G.; Zhang, Q.-J.; Li, K.; Zhang, D.; Shi, C.; Gao, L.-Z.

10.1101/2020.02.22.960880 — genomics — Posted on 2020-02-23

954 Environmental and geographic data optimize ex situ collections and the preservation of adaptive evolutionary potential

Di Santo, L. N.; Hamilton, J. A.

10.1101/2020.02.22.960989 — genomics — Posted on 2020-02-23

955 Tree diversity effects on forest productivity increase through time because of spatial partitioning

Tatsumi, S.

10.1101/2020.02.20.958553 — ecology — Posted on 2020-02-23

956 LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium

Oudhoff, M. J.; Zwiggelaar, R.; Lindholm, H.; Fosslie, M.; Pedersen, M. T.; Ohta, Y.; Diez-Sanchez, A.; Martin-Alonso, M.; Ostrop, J.; Spanjers, R.; Nazmi, K.; Rye, M. B.; Drablos, F.; Arrowsmith, C.; Jensen, K. B.; Dahl, J. A.; Sato, T.; Matano, M.; Kvaloy, E.; Parmar, N.

10.1101/2020.02.20.958363 — developmental biology — Posted on 2020-02-23

957 A Sequence-Pair-Classification-Based Method For Detecting And Correcting Under-Clustered Gene Families

Yadav, A.; Fernandez-Baca, D.; Cannon, S. B.

10.1101/2020.02.22.942557 — bioinformatics — Posted on 2020-02-23

958 AutoGeneS: Automatic gene selection using multi-objective optimization for RNA-seq deconvolution

Aliee, H.; Theis, F. J.

10.1101/2020.02.21.940650 — bioinformatics — Posted on 2020-02-23

959 Supervising the PhD: identifying common mismatches in expectations between candidate and supervisor to improve research training outcomes

Cardilini, A. P.; Risley, A.; Richardson, M. F.

10.1101/2020.02.20.958520 — scientific communication and education — Posted on 2020-02-23

960 Methods for Running a Successful Women-in-STEM Organization on an Academic Campus

Rupert, D.; Nowlan, A. C.; Tam, O. H.; Gale Hammell, M.

10.1101/2020.02.20.958629 — scientific communication and education — Posted on 2020-02-23

961 Loss of rice PARAQUAT TOLERANCE 3 confers enhanced resistance to abiotic stresses and increases grain yield in field

Alfatih, A.; Wu, J.; Jan, S. U.; Zhang, Z.-S.; Xia, J.-Q.; Xiang, C.

10.1101/2020.02.22.961151 — plant biology — Posted on 2020-02-23

962 Perturbation of GABA Biosynthesis Links Cell Cycle to Control Arabidopsis thaliana Leaf Development

Yu, G.

10.1101/2020.02.21.960393 — plant biology — Posted on 2020-02-23

963 Genome-wide analysis of Escherichia coli fitness determinants in a cross-feeding mutualism with Rhodopseudomonas palustris

LaSarre, B.; Deutschbauer, A. M.; Love, C. E.; McKinlay, J. B.

10.1101/2020.02.20.958660 — microbiology — Posted on 2020-02-23

964 A stronger transcription regulatory circuit of HIV-1C drives rapid establishment of latency with implications for the direct involvement of Tat

Chakraborty, S.; Kabi, M.; Ranga, U.

10.1101/2020.02.20.958892 — microbiology — Posted on 2020-02-23

965 Dissimilatory Nitrate Reduction To Ammonium In The Cable Bacterium Ca. Electronema Sp. GS

Marzocchi, U.; Thorup, C.; Dam, A.-S.; Schramm, A.; Risgaard-Petersen, N.

10.1101/2020.02.22.960823 — microbiology — Posted on 2020-02-23

966 Highly reproducible characterization of Escherichia coli tRNA epitranscriptome with a simple method of library preparation for deep sequencing

Wang, J.; Toffano-Nioche, C.; Lorieux, F.; Gautheret, D.; Lehmann, J.

10.1101/2020.02.21.958157 — genomics — Posted on 2020-02-23

967 Integrated decoding hematopoiesis and leukemogenesis at single-cell resolution and its clinical implication

Qin, P.; Pang, Y.; Hou, W.; Fu, R.; Zhang, Y.; Wang, X.; Meng, G.; Liu, Q.; Zhu, X.; Hong, N.; Cheng, T.; Jin, W.

10.1101/2020.02.21.960401 — genomics — Posted on 2020-02-23

968 HOW TO MEASURE THE INFLUENCE OF LANDSCAPE ON POPULATION GENETIC STRUCTURE: DEVELOPING RESISTANCE SURFACES USING A PATTERN-ORIENTED MODELING APPROACH

Souza, K.; Pinto-Ledezma, J. N.; Pires de Campos Telles, M.; Nascimento Soares, T.; Chaves, L.; Dobrovolski, R.; Felizola Diniz-Filho, J. A.

10.1101/2020.02.20.958637 — genetics — Posted on 2020-02-23

969 Phylogenetic and ontogenetic changes of the anatomical organization and modularity in the skull of archosaurs.

Lee, H. W.; Esteve-Altava, B.; Abzhanov, A.

10.1101/2020.02.21.960435 — evolutionary biology — Posted on 2020-02-23

970 Polyploidization enhancing genetic recombination of the ancestral diploid genome in the evolution of hexaploid wheat

Wan, H.; Li, J.; Ma, S.; Wang, Q.; Zhu, X.; Liu, Z.; Yang, F.; Yang, M.; Zheng, J.; Li, S.; Luo, J.; Yang, W.

10.1101/2020.02.21.958991 — evolutionary biology — Posted on 2020-02-23

971 QMaker: Fast and accurate method to estimate empirical models of protein evolution

Minh, B. Q.; Dang, C. C.; Vinh, L. S.; Lanfear, R.

10.1101/2020.02.20.958819 — evolutionary biology — Posted on 2020-02-23

972 Microbial association networks give relevant insights into plant pathobiomes

Pauvert, C.; Fort, T.; Calonnec, A.; Faivre d'Arcier, J.; Chancerel, E.; Massot, M.; Chiquet, J.; Robin, S.; Bohan, D. A.; Vallance, J.; Vacher, C.

10.1101/2020.02.21.958033 — ecology — Posted on 2020-02-23

973 Molecular Survey for Selected Viral Pathogens in Wild Leopard Cats (Prionailurus bengalensis) in Taiwan with an Emphasis on the Spatial and Temporal Dynamics of Carnivore Protoparvovirus 1

Chen, C.-C.; Chang, A.-M.; Chen, W.-J.; Chang, P.-J.; Lai, Y.-C.; Lee, H.-H.

10.1101/2020.02.21.960492 — ecology — Posted on 2020-02-23

974 Leveraging Heterogeneous Network Embedding for Metabolic Pathway Prediction

M. A. Basher, A.; Hallam, S.

10.1101/2020.02.20.940205 — bioinformatics — Posted on 2020-02-23

975 Predicting and Visualizing STK11 Mutation in Lung Adenocarcinoma Histopathology Slides Using Deep Learning

Hong, R.; Liu, W.; Fenyö, D.

10.1101/2020.02.20.956557 — bioinformatics — Posted on 2020-02-23

976 GreenMaps: a Tool for Addressing the Wallacean Shortfall in the Global Distribution of Plants

Daru, B. H.

10.1101/2020.02.21.960161 — ecology — Posted on 2020-02-23

977 Genome-wide Identification and Analysis of Enhancer Regulated microRNAs Across 31 Human Tissues

Tang, F.; Lang, M.; Wang, W.; Li, C.; Tan, Z. t.; Yue, J.; Guo, Z.

10.1101/2020.02.21.960351 — bioinformatics — Posted on 2020-02-23

978 Genetic factors outside the metabolic cluster for plastid-derived sesquiterpenes are required to pursuit arthropod-resistant tomatoes

Therezan, R.; Kortbeek, R.; Vendemiatti, E.; Legarrea, S.; de Alencar, S. M.; Schuurink, R.; Bleeker, P.; Peres, L. E. P.

10.1101/2020.02.21.960112 — plant biology — Posted on 2020-02-23

979 A novel protein complex that regulates active DNA demethylation in Arabidopsis

Liu, P.; Nie, W.-F.; Xiong, X.; Wang, Y.; Jiang, Y.; Huang, P.; Lin, X.; Qin, G.; Huan, H.; Niu, Q.; Du, J.; Lang, Z.; Zhu, J.-K.

10.1101/2020.02.21.958371 — plant biology — Posted on 2020-02-23

980 Genome wide association study reveals plant loci controlling heritability of the rhizosphere microbiome

Deng, S.; Caddell, D. F.; Yang, J.; Dahlen, L.; Washington, L.; Coleman-Derr, D.

10.1101/2020.02.21.960377 — plant biology — Posted on 2020-02-23

981 Plant SYP12 syntaxins mediate evolutionarily conserved general immunity to filamentous pathogens

Rubiato, H. M.; O'Connell, R. J.; Nielsen, M. E.

10.1101/2020.02.21.957480 — plant biology — Posted on 2020-02-23

982 Stomatal density affects gas diffusion and CO2 assimilation dynamics in Arabidopsis under fluctuating light

Sakoda, K.; Yamori, W.; Shimada, T.; Sugano, S. S.; Hara-Nishimura, I.; Tanaka, Y.

10.1101/2020.02.20.958603 — plant biology — Posted on 2020-02-23

983 Rice NIN-LIKE PROTEIN 1 Rapidly Responds to Nitrogen Deficiency and Improves Yield and Nitrogen Use Efficiency

Alfatih, A.; Wu, J.; Zhang, Z.-S.; Xia, J.-Q.; Jan, S. U.; Yu, L.-H.; Xiang, C.

10.1101/2020.02.22.961193 — plant biology — Posted on 2020-02-23

984 In silico characteration of GmSOS1 provides a comprehensive understaning for its role in soybean salt tolerance

Yang, L.-Y.; Mei, Z.-C.; Liu, Z.-M.; Hou, X.-Z.; Xie, L.-J.

10.1101/2020.02.21.951061 — plant biology — Posted on 2020-02-23

985 Altered directed functional connectivity of the right amygdala in depression: high-density EEG study

Damborska, A.; Honzirkova, E.; Bartecek, R.; Horinkova, J.; Fedorova, S.; Ondrus, S.; Michel, C.; Rubega, M.

10.1101/620252 — neuroscience — Posted on 2020-02-23

986 A single gene expressed in fibroblastic reticular cells predicts response to cancer immunotherapy

Biasci, D.; Thaventhiran, J.; Tavare, S.

10.1101/2020.02.19.955666 — immunology — Posted on 2020-02-23

987 Exploring High-Dimensional Biological Data with Sparse Contrastive Principal Component Analysis

Boileau, P.; Hejazi, N. S.; Dudoit, S.

10.1101/836650 — genomics — Posted on 2020-02-23

988 Fingerprinting of hatchery haplotypes by whole-mitogenome sequencing improves genetic studies of masu salmon Oncorhynchus masou masou

Kato-Unoki, Y.; Umemura, K.; Tashiro, K.

10.1101/2020.01.30.926691 — genetics — Posted on 2020-02-23

989 Cells reshape habitability of temperature by secreting antioxidants to help each other replicate and avoid population extinction

Laman Trip, D. S.; Youk, H.

10.1101/726463 — systems biology — Posted on 2020-02-23

990 Heterosynaptic Plasticity Determines the Set-Point for Cortical Excitatory-Inhibitory Balance

Field, R.; D'amour, J.; Tremblay, R.; Miehl, C.; Rudy, B.; Gjorgjieva, J.; Froemke, R.

10.1101/282012 — neuroscience — Posted on 2020-02-23

991 Alteration of Power Law Scaling of Spontaneous Brain Activity in Schizophrenia

Lee, Y.-J.; Huang, S.-Y.; Lin, C.-P.; Tsai, S.-J.; Yang, A. C.

10.1101/2020.02.13.946657 — neuroscience — Posted on 2020-02-23

992 Data architecture for a large-scale neuroscience collaboration

The International Brain Laboratory, ; Bonacchi, N.; Chapuis, G.; Churchland, A. K.; Harris, K. D.; Hunter, M.; Rossant, C.; Sasaki, M.; Shen, S.; Steinmetz, N. A.; Walker, E. Y.; Winter, O.; Wells, M.

10.1101/827873 — neuroscience — Posted on 2020-02-23

993 Nigro-Thalamic Projection Controls Timing of Action Initiation

Catanese, J.; Jaeger, D.

10.1101/2020.01.12.903500 — neuroscience — Posted on 2020-02-23

994 Oecophyllibacter saccharovorans gen. nov. sp. nov., a bacterial symbiont of the weaver ant Oecophylla smaragdina with a plasmid-borne sole rrn operon

Chua, K.-O.; See-Too, W.-S.; Tan, J.-Y.; Song, S.-L.; Yong, H.-S.; Yin, W.-F.; Chan, K.-G.

10.1101/2020.02.15.950782 — microbiology — Posted on 2020-02-23

995 Large scale genome-wide association study reveals that drought induced lodging in grain sorghum is associated with plant height and traits linked to carbon remobilisation

Wang, X.; Mace, E. S.; Tao, Y.; Cruickshank, A.; Hunt, C.; Hammer, G. L.; Jordan, D. R.

10.1101/865667 — genetics — Posted on 2020-02-23

996 Novel step selection analyses on energy landscapes reveal how linear features alter migrations of soaring birds

Eisaguirre, J. M.; Booms, T. L.; Barger, C. P.; Lewis, S. B.; Breed, G. A.

10.1101/805374 — ecology — Posted on 2020-02-23

997 Machine Source Localization of Tursiops truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

Woodward, S. F.; Reiss, D.; Magnasco, M.

10.1101/606673 — biophysics — Posted on 2020-02-23

998 Systematic functional analysis of Rab GTPasesreveals limits of neuronal robustness in Drosophila

Kohrs, F. E.; Daumann, I.-M.; Pavlovic, B.; Jin, E. J.; Lin, S.-C.; Port, F.; Kiral, F. R.; Wolfenberg, H.; Mathejczyk, T. F.; Chan, C.-C.; Boutros, M.; Hiesinger, P. R.

10.1101/2020.02.21.959452 — neuroscience — Posted on 2020-02-22

999 Leading-edge VASP clusters assemble at sites containing lamellipodin and exhibit size-dependent instability

Cheng, K. W.; Mullins, D.

10.1101/2020.02.21.960229 — cell biology — Posted on 2020-02-22

1000 Calcium Sensors ALG-2 And Peflin Bind ER Exit Sites In Alternate States To Modulate Secretion In Response To Calcium Signaling

Sargeant, J.; Costain, T.; Madreiter-Sokolowski, C. T.; Gordon, D. E.; Peden, A. A.; Malli, R.; Graier, W. F.; Hay, J. C.

10.1101/2020.02.22.944264 — cell biology — Posted on 2020-02-22

1001 Evolutionarily conserved regulation of embryonic fast-twitch skeletal muscle differentiation by Pbx factors

Farr, G. H.; Li, B.; Risolino, M.; Johnson, N. M.; Yao, Z.; Kao, R. M.; Majesky, M. W.; Tapscott, S. J.; Selleri, L.; Maves, L.

10.1101/2020.02.21.960484 — developmental biology — Posted on 2020-02-22

1002 Global proteomics of Ubqln2-based murine models of ALS

Whiteley, A. M.; Prado, M. A.; de Poot, S. A. H.; Paulo, J. A.; Ashton, M.; Dominguez, S.; Weber, M.; Ngu, H.; Szpyt, J.; Jedrychowski, M. P.; Easton, A.; Gygi, S. P.; Kurz, T.; Monteiro, M. J.; Brown, E. J.; Finley, D.

10.1101/2020.02.22.956524 — cell biology — Posted on 2020-02-22

1003 Cytoplasmic sharing through apical membrane remodeling

Peterson, N. G.; Stormo, B.; Schoenfelder, K.; King, J.; Lee, R. R.; Fox, D. T.

10.1101/2020.02.22.960187 — cell biology — Posted on 2020-02-22

1004 Light-inducible generation of membrane curvature in live cells with engineered BAR domain proteins

Jones, T. E.; Liu, A.; Cui, B.

10.1101/2020.02.20.958611 — synthetic biology — Posted on 2020-02-22

1005 Automated continuous evolution of proteins in vivo

Zhong, Z.; Wong, B. G.; Ravikumar, A.; Arzumanyan, G. A.; Khalil, A. S.; Liu, C. C.

10.1101/2020.02.21.960328 — synthetic biology — Posted on 2020-02-22

1006 Efficient Retroelement-Mediated DNA Writing in Bacteria

Farzadfard, F.; Gharaei, N.; Citorik, R. J.; Lu, T. K.

10.1101/2020.02.21.958983 — synthetic biology — Posted on 2020-02-22

1007 Inactivating porcine coronavirus before nuclei acid isolation with the temperature higher than 56 °C damages its genome integrity seriously

Zhang, Q.; Zhao, Q.

10.1101/2020.02.20.958785 — molecular biology — Posted on 2020-02-22

1008 No more business as usual: agile and effective responses to emerging pathogen threats require open data and open analytics

Galaxy and HyPhy developments teams, ; Nekrutenko, A.; Kosakovsky Pond, S. L.

10.1101/2020.02.21.959973 — evolutionary biology — Posted on 2020-02-22

1009 Systematic determination of the mitochondrial proportion in human and mice tissues for single-cell RNA sequencing data quality control

Osorio, D.; Cai, J. J.

10.1101/2020.02.20.958793 — bioinformatics — Posted on 2020-02-22

1010 Bile acid supplementation improves murine pancreatitis in association with the gut microbiota

Wan, Y.-D.; Zhu, R.-X.; Pan, X.-T.; Sun, T.-W.

10.1101/2020.02.13.948547 — bioinformatics — Posted on 2020-02-22

1011 Voluntary and involuntary orienting of attention elicit similar lateralized changes in alpha activity and slow potential shifts over visual cortex

Keefe, J. M.; Stoermer, V. S.

10.1101/2019.12.12.874818 — neuroscience — Posted on 2020-02-22

1012 Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells

Hawkins, F. J.; Suzuki, S.; Beermann, M. L.; Barilla, C.; Wang, R.; Villacorta-Martin, C.; Berical, A.; Jean, J. C.; LeSuer, J.; Simone-Roach, C.; Tang, Y.; Schlaeger, T. M.; Crane, A.; Huang, S. X. L.; Rab, A.; Sorscher, E. J.; Horani, A.; Brody, S. L.; Davis, B. R.; Kotton, D. N.

10.1101/2020.02.21.959395 — developmental biology — Posted on 2020-02-22

1013 Silencing branched-chain ketoacid dehydrogenase or treatment with branched-chain ketoacids ex vivo inhibits muscle insulin signaling

Biswas, D.; Dao, K. T.; Mercer, A.; Cowie, A. M.; Duffley, L.; El Hiani, Y.; Kienesberger, P. C.; Pulinilkunnil, T.

10.1101/2020.02.21.960153 — cell biology — Posted on 2020-02-22

1014 Proteasome-Bound UCH37 Debranches Ubiquitin Chains to Promote Degradation

Deol, K. K.; Crowe, S. O.; Du, J.; Bisbee, H. A.; Guenette, R. G.; Strieter, E. R.

10.1101/2020.02.21.960088 — biochemistry — Posted on 2020-02-22

1015 APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers

Fennell, L.; Kane, A.; Liu, C.; Mckeone, D.; Fernando, W.; Su, C.; Bond, C.; Jamieson, S.; Dumenil, T.; Patch, A.-M.; Kazakoff, S.; Pearson, J.; Waddell, N.; Leggett, B.; Whitehall, V.

10.1101/2020.02.16.942904 — cancer biology — Posted on 2020-02-22

1016 Automated Workflow For Peptide-level Quantitation From DIA/ SWATH-MS Data

Gupta, S.; Rost, H.

10.1101/2020.01.21.914788 — bioinformatics — Posted on 2020-02-22

1017 Origin of a novel CYP20A1 transcript isoform through multiple Alu exaptations creates a potential miRNA sponge

Bhattacharya, A.; Jha, V.; Singhal, K.; Fatima, M.; Singh, D.; Chaturvedi, G.; Dholakia, D.; Kutum, R.; Pandey, R.; Bakken, T. E.; Seth, P.; Pillai, B.; Mukerji, M.

10.1101/618645 — evolutionary biology — Posted on 2020-02-22

1018 Loss of Corneal Raver2 Expression in Aniridia Associated Keratopathy

Das, S. K.; Carroll, L.; Holt, D.; zhang, X.; Uehara, H.; Archer, B.; Ambati, J.; Ambati, B. K.

10.1101/2020.02.21.959585 — developmental biology — Posted on 2020-02-22

1019 A non-canonical Hippo pathway regulates spindle disassembly and cytokinesis during meiosis in Saccharomyces cerevisiae

Paulissen, S. M.; Hunt, C. A.; Slubowski, C. J.; Yu, Y.; Truong, D.; Mucelli, X.; Nguyen, H. T.; Newman-Toledo, S.; Neiman, A. M.; Huang, L. S.

10.1101/2020.02.21.959619 — cell biology — Posted on 2020-02-22

1020 Decreased Colonic Activin Receptor Like Kinase 1 Disrupts Epithelial Barrier integrity and is associated with a poor clinical outcome in Crohns disease

Toyonaga, T.; Keith, B. P.; Barrow, J.; Schaner, M. S.; Wolber, E. A.; Beasley, C.; Huling, J.; Wang, Y.; Allbritton, N. L.; Chaumont, N.; Sadiq, T. S.; Koruda, M. J.; Rahbar, R.; Furey, T. S.; Sethupathy, P.; Sheikh, S. Z.

10.1101/2020.02.21.960070 — cell biology — Posted on 2020-02-22

1021 Matrix metalloproteinase-2 mediates ribosomal RNA transcription by cleaving nucleolar histones

Ali, M. A. M.; Garcia-Vilas, J. A.; Cromwell, C. R.; Hubbard, B. P.; Hendzel, M. J.; Schulz, R.

10.1101/2020.02.21.958280 — cell biology — Posted on 2020-02-22

1022 The wasting-associated metabolite succinate disrupts myogenesis and impairs skeletal muscle regeneration

Arneson, P. C.; Hogan, K. A.; Shin, A. M.; Samani, A.; Jatoi, A.; Doles, J. D.

10.1101/822338 — cancer biology — Posted on 2020-02-22

1023 Accumulative deamidation of human lens protein γS-crystallin leads to partially unfolded intermediates with enhanced aggregation propensity

Vetter, C. J.; Thorn, D.; Wheeler, S. G.; Mundorff, C.; Halverson-Kolkind, K.; Carver, J. A.; David, L. L.; Lampi, K. J.

10.1101/2020.02.21.960237 — biochemistry — Posted on 2020-02-22

1024 Metabolic defects cause hyperactive mitochondria and Parkinson disease-like traits

Mor, D. E.; Sohrabi, S.; Kaletsky, R.; Keyes, W.; Kalia, V.; Miller, G. W.; Murphy, C. T.

10.1101/2020.02.20.958322 — neuroscience — Posted on 2020-02-22

1025 Drosophila larval epidermal cells only exhibit epidermal aging when they persist to the adult stage

Wang, Y.; Burra, S.; Galko, M. J.

10.1101/2020.02.21.959783 — cell biology — Posted on 2020-02-22

1026 Reprogramming of Human Cells to Pluripotency Induces CENP-A Chromatin Depletion

Milagre, I.; Pereira, C.; Oliveira, R.; Jansen, L. E. T.

10.1101/2020.02.21.960252 — cell biology — Posted on 2020-02-22

1027 Biased localization of actin binding proteins by actin filament conformation

Harris, A. R.; Jreij, P.; Belardi, B.; Bausch, A.; Fletcher, D. A.

10.1101/2020.02.21.959791 — biophysics — Posted on 2020-02-22

1028 In situ structure determination of virus capsids imaged within cell nuclei by correlative light and cryo-electron tomography.

Vijayakrishnan, S.; McElwee, M.; Loney, C.; Rixon, F. J.; Bhella, D.

10.1101/2020.02.06.936948 — biophysics — Posted on 2020-02-22

1029 Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor

Olson, L. J.; Misra, S.; Ishihara, M.; Battaile, K.; Grant, O.; Sood, A.; Woods, R. J.; Kim, J.-J. P.; Tiemeyer, M.; Ren, G.; Sharp, J.; Dahms, N. M.

10.1101/2020.02.21.959957 — biochemistry — Posted on 2020-02-22

1030 Molecular Characterization of invasive Enterobacteriaceae from Pediatric Patients in Central and Northwestern Nigeria

Duru, C.; Olanipekun, G.; Odili, V.; Ajose, T.

10.1101/2020.02.21.959338 — molecular biology — Posted on 2020-02-21

1031 Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast

Scherer, A. K.; Blair, B. A.; Park, J.; Seman, B. G.; Kelley, J. B.; Wheeler, R. T.

10.1101/2020.02.21.959387 — microbiology — Posted on 2020-02-21

1032 Autophagy-associated Production of Antimicrobial Peptides hBD1 and LL37 Exhibits Anti-Bacillus Calmette-Guerin Effects in Lung Epithelial Cells.

Wang, R.-n.; Liu, H.-l.; Chen, Y.-x.; Wen, Q.; Zhou, X.-y.; Wang, J.-l.; Yang, J.-h.; Li, Y.-f.; Han, Z.-y.; Ma, L.

10.1101/2020.02.21.959361 — immunology — Posted on 2020-02-21

1033 SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

Diedrich, C. R.; Rutledge, T.; Maiello, P.; Baranowski, T. M.; White, A. G.; Borish, H. J.; Karell, P.; Hopkins, F.; Brown, J.; Fortune, S. M.; Flynn, J. L.; Ambrose, Z.; Lin, P. L.

10.1101/2020.02.21.959353 — immunology — Posted on 2020-02-21

1034 Junctional and cytoplasmatic contributions in wound healing

Mosaffa, P.; Tetley, R. J.; Rodriguez-Ferran, A.; Mao, Y.; Munoz Romero, J. J.

10.1101/2020.02.21.959379 — cell biology — Posted on 2020-02-21

1035 New Tricks for an old molecule: Preserved antibacterial activity of ribosomal protein S15 during evolution

Zhang, S.; Qu, B.; Ma, Z.; Yao, L.; Gao, Z.

10.1101/2020.02.21.959346 — immunology — Posted on 2020-02-21

1036 Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

Hahn, J.; Fu, Y.-P.; Brown, M. R.; Bis, J. C.; de Vries, P. S.; Feitosa, M. F.; Yanek, L. R.; Weiss, S.; Giulianini, F.; Smith, A. V.; Guo, X.; Bartz, T. M.; Becker, D. M.; Becker, L. C.; Boerwinkle, E.; Brody, J. A.; Chen, Y.-D. I.; Franco, O. H.; Grove, M.; Harris, T. B.; Hofman, A.; Hwang, S.-J.; Kral, B. G.; Launer, L. J.; Markus, M. R. P.; Rice, K. M.; Rich, S. S.; Ridker, P. M.; Rivadeneira, F.; Rotter, J. I.; Sotoodehnia, N.; Taylor, K. D.; Uitterlinden, A. G.; Völker, U.; Völzke, H.; Yao, J.; Chasman, D. I.; Dörr, M.; Gudnason, V.; Mathias, R. A.; Post, W.; Psaty, B. M.; Dehghan, A.

10.1101/2020.02.21.959312 — genetics — Posted on 2020-02-21

1037 Telomerase inhibition causes premature senescence of fetal guinea pig muscle cells

Hallows, S.; Regnault, T.; Betts, D. H.

10.1101/2020.02.21.959320 — cell biology — Posted on 2020-02-21

1038 Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

Thao, T. T. N.; Labroussaa, F.; Ebert, N.; V'kovski, P.; Stalder, H.; Portmann, J.; Kelly, J.; Steiner, S.; Holwerda, M.; Kratzel, A.; Gultom, M.; Laloli, L.; Huesser, L.; Wider, M.; Pfaender, S.; Hirt, D.; Cippa, V.; Crespo-Pomar, S.; Schroeder, S.; Muth, D.; Niemeyer, D.; Mueller, M. A.; Drosten, C.; Dijkman, R.; Jores, J.; Thiel, V.

10.1101/2020.02.21.959817 — microbiology — Posted on 2020-02-21

1039 Functional pangenome analysis provides insights into the origin, function and pathways to therapy of SARS-CoV-2 coronavirus

Alam, I.; Kamau, A. K.; Kulmanov, M.; Arold, S. T.; Pain, A. T.; Gojobori, T.; Duarte, C. M.

10.1101/2020.02.17.952895 — genomics — Posted on 2020-02-21

1040 Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

10.1101/2020.02.21.959312 — genetics — Posted on 2020-02-21

1041 An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells

Jones, R. D.; Qian, Y.; Siciliano, V.; DiAndreth, B.; Huh, J.; Weiss, R.; Del Vecchio, D.

10.1101/867028 — synthetic biology — Posted on 2020-02-21

1042 Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function

Helmin, K. A.; Morales-Nebreda, L.; Torres Acosta, M. A.; Anekalla, K. R.; Chen, S.-Y.; Abdala-Valencia, H.; Politanska, Y.; Cheresh, P.; Akbarpour, M.; Steinert, E. M.; Weinberg, S. E.; Singer, B. D.

10.1101/2020.02.03.926949 — immunology — Posted on 2020-02-21

1043 How do Dachsous and Fat polarise cells in the larval abdomen of Drosophila?

Pietra, S.; Ng, K.; Lawrence, P. A.; Casal, J.

10.1101/2020.02.21.959213 — developmental biology — Posted on 2020-02-21

1044 A Single Cell Transcriptomic Atlas Characterizes Aging Tissues in the Mouse

The Tabula Muris Consortium, ; Pisco, A. O.; McGeever, A.; Schaum, N.; Karkanias, J.; Neff, N. F.; Darmanis, S.; Wyss-Coray, T.; Quake, S. R.

10.1101/661728 — cell biology — Posted on 2020-02-21

1045 Keeping up with the genomes: efficient learning of our increasing knowledge of the tree of life

Zhao, Z.; Cristian, A.; Rosen, G. L.

10.1101/758755 — bioinformatics — Posted on 2020-02-21

1046 A Vibrio cholerae Core Genome Multilocus Sequence Typing Scheme to Facilitate the Epidemiological Study of Cholera

Liang, K. Y. H.; Orata, F. D.; Islam, M. T.; Nasreen, T.; Alam, M.; Tarr, C. L.; Boucher, Y. F.

10.1101/2020.01.27.919118 — microbiology — Posted on 2020-02-21

1047 On deleterious mutations in perennials: inbreeding depression, mutation load and life-history evolution

Lesaffre, T.; Billiard, S.

10.1101/865220 — evolutionary biology — Posted on 2020-02-21

1048 Mitofusin 2 regulates neutrophil adhesive migration via suppressing Rac activation

Zhou, W.; Hsu, A. Y.; Wang, T.; Jeffries, J.; Mohammad, H. T.; Wang, X.; Umulis, D. M.; Seleem, M. N.; Deng, Q.

10.1101/608091 — cell biology — Posted on 2020-02-21

1049 Fibroblastic reticular cells predict response to cancer immunotherapy

Biasci, D.; Tavare, S.; Thaventhiran, J.

10.1101/2020.02.19.955666 — immunology — Posted on 2020-02-21

1050 A GT-seq panel for walleye (Sander vitreus) provides a generalized workflow for efficient development and implementation of amplicon panels in non-model organisms.

Bootsma, M.; Gruenthal, K. M.; McKinney, G. J.; Simmons, L.; Miller, L.; Sass, G. G.; Larson, W. A.

10.1101/2020.02.13.948331 — genomics — Posted on 2020-02-21

1051 Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM based SCFS

Viji Babu, P. K.; Mirastschijski, U.; Belge, G.; Radmacher, M.

10.1101/2020.02.11.943597 — biophysics — Posted on 2020-02-21

1052 Diastolic Dysfunction Accompanies Alterations in Myocardial Structure, Cellular Composition and Macrophage Polarization in Survivors of Ionizing Radiation Exposure

Michalson, K. T.; Dugan, G. O.; Caudell, D. L.; Kitzman, D. W.; Cline, J. M.; Register, T. C.

10.1101/2020.02.18.953190 — pathology — Posted on 2020-02-21

1053 Differential contributions of left-hemispheric language regions to basic semantic composition

Graessner, A.; Zaccarella, E.; Hartwigsen, G.

10.1101/2019.12.11.872457 — neuroscience — Posted on 2020-02-21

1054 Resolving the connectome - Spectrally-specific functional connectivity networks and their distinct contributions to behaviour

Becker, R.; Hervais-Adelman, A.

10.1101/700278 — neuroscience — Posted on 2020-02-21

1055 Helicobacter small RNA regulates host adaptation and carcinogenesis

Kinoshita-Daitoku, R.; Kiga, K.; Otsubo, R.; Ogura, Y.; Sanada, T.; Bo, Z.; Phuoc, T. V.; Okano, T.; Iida, T.; Yokomori, R.; Kuroda, E.; Hirukawa, S.; Tanaka, M.; Sood, A.; Subsomwong, P.; Ashida, H.; Binh, T. T.; Nguyen, L. T.; Van, K. V.; Ho, D. Q. D.; Nakai, K.; Suzuki, T.; Yamaoka, Y.; Hayashi, T.; Mimuro, H.

10.1101/2020.02.15.950279 — microbiology — Posted on 2020-02-21

1056 Epiclomal: probabilistic clustering of sparse single-cell DNA methylation data

P. E. de Souza, C.; Andronescu, M.; Masud, T.; Kabeer, F.; Biele, J.; Laks, E.; Lai, D.; Ye, P.; Brimhall, J.; Wang, B.; Su, E.; Hui, T.; Cao, Q.; Wong, M.; Moksa, M.; Moore, R. A.; Hirst, M.; Aparicio, S.; Shah, S. P.

10.1101/414482 — genomics — Posted on 2020-02-21

1057 Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies

Ainsworth, H. C.; Howard, T. D.; Langefeld, C. D.

10.1101/837245 — genetics — Posted on 2020-02-21

1058 Estimating and accounting for genotyping errors in RAD-seq experiments

Bresadola, L.; Link, V.; Buerkle, A.; Lexer, C.; Wegmann, D.

10.1101/587428 — evolutionary biology — Posted on 2020-02-21

1059 A simple method to quantify protein abundances from one thousand cells

Vitrinel, B.; Iannitelli, D. E.; Mazzoni, E. O.; Christiaen, L.; Vogel, C.

10.1101/753582 — systems biology — Posted on 2020-02-21

1060 Inter-slice leakage and intra-slice aliasing in simultaneous multi-slice echo-planar images

McNabb, C. B.; Lindner, M.; Shen, S.; Burgess, L. G.; Murayama, K.; Johnstone, T.

10.1101/458042 — neuroscience — Posted on 2020-02-21

1061 Intra-articular AAV-PHP.S mediated chemogenetic targeting of knee-innervating dorsal root ganglion neurons alleviates inflammatory pain in mice.

Chakrabarti, S.; Pattison, L. A.; Doleschall, B.; Rickman, R.; Blake, H.; Callejo, G.; Heppenstall, P. A.; Smith, E. S. J.

10.1101/2020.02.08.939066 — neuroscience — Posted on 2020-02-21

1062 Multi-omic surveillance of Escherichia coli and Klebsiella spp. in hospital sink drains and patients

Constantinides, B.; Chau, K. K.; Quan, T. P.; Rodger, G.; Andersson, M.; Jeffery, K. J.; Lipworth, S.; Gweon, S.; Peniket, A.; Pike, G.; Millo, J.; Byukusenge, M.; Holdaway, M.; Gibbons, C.; Mathers, A. J.; Crook, D. W.; Peto, T. E.; Walker, A. S.; Stoesser, N.

10.1101/2020.02.19.952366 — microbiology — Posted on 2020-02-21

1063 Contrasting population genetics of cattle- and buffalo- derived Theileria annulata causing tropical theileriosis

Chaudhry, U.; Ali, Q.; Zheng, L.; Rashid, I.; Shabbir, M. Z.; Nauman, M.; Ashraf, K.; Evans, M.; Rafiq, S.; Oneeb, M.; Morrison, I.; Sargison, N. D.

10.1101/2020.01.10.902031 — genetics — Posted on 2020-02-21

1064 Scaling of organ masses in mammals and birds: phylogenetic signal and implications for metabolic rate scaling

Antoł, A.; Kozłowski, J.

10.1101/694067 — evolutionary biology — Posted on 2020-02-21

1065 Unstable Population Dynamics in Obligate Co-Operators

Halloway, A.; Malone, M.; Brown, J. S.

10.1101/208934 — ecology — Posted on 2020-02-21

1066 Interplay between the paradox of enrichment and nutrient cycling in food webs

Quevreux, P.; Barot, S.; Thebault, E.

10.1101/276592 — ecology — Posted on 2020-02-21

1067 Colonization and extinction dynamics match the distribution of European trees at continental scale

Guyennon, A.; Reineking, B.; Dahlgren, J.; Lehtonen, A.; Ratcliffe, S.; Ruiz-Benito, P.; Zavala, M. A.; Kunstler, G.

10.1101/748483 — ecology — Posted on 2020-02-21

1068 Signaling compartment at the ciliary tip is formed and maintained by intraflagellar transport and functions as sensitive salt detector

van der Burght, S. N.; Rademakers, S.; Johnson, J.-L.; Li, C.; Kremers, G.-J.; Houtsmuller, A. B.; Leroux, M. R.; Jansen, G.

10.1101/861955 — cell biology — Posted on 2020-02-21

1069 Identifying Severe Stroke Patients Likely to Benefit From Intervention Despite a Delay of a Day

Gonzalez, R. G.; Silva, G. S.; He, J.; Sadaghiani, S.; Wu, O.; Singhal, A. B.

10.1101/526947 — clinical trials — Posted on 2020-02-21

1070 Direct Observation of a Coil-to-Helix Contraction Triggered by Vinculin Binding to Talin

Tapia-Rojo, R.; Alonso-Caballero, A.; Fernandez, J. M.

10.1101/741884 — biophysics — Posted on 2020-02-21

1071 Dynamic coordination of the perirhinal cortical neurons supports coherent representations between task epochs

Ohnuki, T.; Osako, Y.; Manabe, H.; Sakurai, Y.; Hirokawa, J.

10.1101/514612 — neuroscience — Posted on 2020-02-21

1072 Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

Watanabe, Y.; Berndsen, Z. T.; Raghwani, J.; Seabright, G. E.; Allen, J. D.; McLellan, J. S.; Wilson, I. A.; Bowden, T. A.; Ward, A. B.; Crispin, M.

10.1101/2020.02.20.957472 — microbiology — Posted on 2020-02-21

1073 Investigating the physical effects in bacterial therapies for avascular tumors

Mascheroni, P.; Meyer-Hermann, M.; Hatzikirou, H.

10.1101/683839 — biophysics — Posted on 2020-02-21

1074 Machine Source Localization of Tursiops truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

Woodward, S. F.; Reiss, D.; Magnasco, M.

10.1101/606673 — biophysics — Posted on 2020-02-21

1075 Deep Neural Networks Carve the Brain at its Joints

Bertolero, M. A.; Bassett, D. S.

10.1101/2020.02.20.958082 — neuroscience — Posted on 2020-02-21

1076 Mapping human laryngeal motor cortex during vocalization

Eichert, N.; Papp, D.; Mars, R. B.; Watkins, K. E.

10.1101/2020.02.20.958314 — neuroscience — Posted on 2020-02-21

1077 Human Influenza A Virus H1N1pdm Full-length Genome Sequencing in USA and Taiwan in 2015-16 Flu Season and Disease Correlation

Liu, H.; Gong, Y.-N.; Shaw-Saliba, K.; Mehoke, T.; Evans, J.; Liu, Z.-Y.; Lewis, M.; Sauer, L.; Thielen, P.; Rothman, R.; Chen, K.-F.; Pekosz, A.

10.1101/2020.02.20.957068 — microbiology — Posted on 2020-02-21

1078 Achieving symptom relief in patients with Myalgic encephalomyelitis by targeting the neuro-immune interface and inducing disease tolerance

Rodriguez, L. S.; Pou, C.; Tadepally, L.; Zhang, J.; Mugabo, C. H.; Wang, J.; Mikes, J.; Olin, A.; Chen, Y.; Rorbach, J.; Juto, J.-E.; Li, T.-Q.; Julin, P.; Brodin, P.

10.1101/2020.02.20.958249 — immunology — Posted on 2020-02-21

1079 Effects of substituents on anticancer activity of thiosemicarbazone against MCF-7 human breast cancer cell line

Sibuh, B. Z.; Taneja, P.; Khanna, S.

10.1101/2020.02.19.955690 — cancer biology — Posted on 2020-02-21

1080 Bound2Learn: A Machine Learning Approach for Classification of DNA-Bound Proteins from Single-Molecule Tracking Experiments

Kapadia, N.; El-Hajj, Z. W.; REYES LAMOTHE, R.

10.1101/2020.02.20.958512 — biophysics — Posted on 2020-02-21

1081 Whole-brain estimates of directed connectivity for human connectomics

Frässle, S.; Manjaly, Z.-M.; Do, C. T.; Kasper, L.; Pruessmann, K. P.; Stephan, K. E.

10.1101/2020.02.20.958124 — neuroscience — Posted on 2020-02-21

1082 Are Antisense Proteins in Prokaryotes Functional?

Ardern, Z.; Neuhaus, K.; Scherer, S.

10.1101/2020.02.20.958058 — microbiology — Posted on 2020-02-21

1083 Mechanism of monoallelic expression and allelic rheostat role of DNA methylation

Gupta, S.; Lafontaine, D. L.; Vigneau, S.; Vinogradova, S.; Mendelevich, A.; Igarashi, K. J.; Bortvin, A.; Alves-Pereira, C. F.; Clement, K.; Pinello, L.; Gnirke, A.; Long, H.; Gusev, A.; Nag, A.; Gimelbrant, A. A.

10.1101/2020.02.20.954834 — genomics — Posted on 2020-02-21

1084 What drives the assembly of plant-associated protist microbiomes?

Dumack, K.; Feng, K.; Flues, S.; Sapp, M.; Schreiter, S.; Grosch, R.; Rose, L.; Deng, Y.; Smalla, K.; Bonkowski, M.

10.1101/2020.02.16.951384 — plant biology — Posted on 2020-02-21

1085 MULTIMAP: Multilingual visual naming test for the mapping of eloquent areas during awake surgeries.

Gisbert-Munoz, S.; Quinones, I.; Amoruso, L.; Timofeeva, P.; Geng, S.; Boudelaa, S.; Pomposo, I.; Gil-Robles, S.; Carreiras, M.

10.1101/2020.02.20.957282 — neuroscience — Posted on 2020-02-21

1086 Parallel cortical-brainstem pathways to attentional analgesia

Oliva, V.; Gregory, R.; Davies, W.-E.; Harrison, L.; Moran, R.; Pickering, A. E.; Brooks, J. C. W.

10.1101/2020.02.20.955161 — neuroscience — Posted on 2020-02-21

1087 Cortical network fingerprint and prediction of stimulation induced speech impairment in essential tremor

Petry-Schmelzer, J. N.; Jergas, H.; Thies, T.; Steffen, J. K.; Reker, P.; Dafsari, H. S.; Muecke, D.; Fink, G. R.; Visser-Vandewalle, V.; Dembek, T. A.; Barbe, M. T.

10.1101/2020.02.20.958470 — neuroscience — Posted on 2020-02-21

1088 Noradrenaline modulates tabula-rasa exploration

Dubois, M.; Habicht, J.; Michely, J.; Moran, R.; Dolan, R.; Hauser, T.

10.1101/2020.02.20.958025 — neuroscience — Posted on 2020-02-21

1089 Influenza-induced oxidative stress sensitizes lung cells to bacterial toxin-mediated necroptosis

Gonzalez-Juarbe, N.; Riegler, A. N.; Jureka, A. S.; Gilley, R. P.; Brand, J.; Trombley, J. E.; Scott, N. R.; Dube, P. H.; Petit, C. M.; Harrod, K. S.; Orihuela, C. J.

10.1101/2020.02.20.957951 — microbiology — Posted on 2020-02-21

1090 Identification of H3N2 NA and PB1-F2 genetic variants and their association with disease symptoms in the 2014-15 influenza season

Blumenkrantz, D.; Mehoke, T.; Hardick, J.; Shaw-Saliba, K.; Liu, H.; Powell, H.; Macias, E.; Evans, J.; Lewis, M.; Medina, R.; Sauer, L. M.; Dugas, A.; DuVal, A.; Lane, A. P.; Gaydos, C.; Rothman, R.; Thielen, P.; Pekosz, A.

10.1101/2020.02.20.956979 — microbiology — Posted on 2020-02-21

1091 Population dynamics of Diatraea spp. Under different climate offer conditions in Colombia.

Arbelaez, J. A.; Soto Giraldo, A.; Castano Villa, G. J.; Vallejo Espinosa, L. F.; Salazar Gutierrez, M. R.; Vargas Orozco, G. A.

10.1101/2020.02.20.957977 — developmental biology — Posted on 2020-02-21

1092 Independent and sensitive gait parameters for objective evaluation in knee and hip osteoarthritis using wearable sensors

Boekesteijn, R. J.; Smolders, J. M. H.; Busch, V. J. J. F.; Geurts, A. C. H.; Smulders, K.

10.1101/2020.02.20.957506 — biophysics — Posted on 2020-02-21

1093 Increasing habitat loss and human disturbances in the world's largest mangrove forest: the impact on plant-pollinator interactions

Akter, A.; Biella, P.; Batary, P.; Klecka, J.

10.1101/2020.02.20.953166 — ecology — Posted on 2020-02-21

1094 Potential T-cell and B-cell Epitopes of 2019-nCoV

Fast, E.; Chen, B.

10.1101/2020.02.19.955484 — microbiology — Posted on 2020-02-21

1095 A single gene expressed in fibroblastic reticular cells predicts response to cancer immunotherapy

Biasci, D.; Tavare, S.; Thaventhiran, J.

10.1101/2020.02.19.955666 — immunology — Posted on 2020-02-21

1096 FGF2 modulates simultaneously the mode, the rate of division and the growth fraction in cultures of Radial Glia

Ledesma-Terron, M.; Peralta-Canadas, N.; Miguez, D. G.

10.1101/707463 — developmental biology — Posted on 2020-02-21

1097 A validated strategy to infer protein biomarkers from RNA-Seq by combining multiple mRNA splice variants and time-delay

Magnusson, R.; Rundquist, O.; Kim, M. J.; Hellberg, S.; Na, C. H.; Benson, M.; Gomez-Cabrero, D.; Kockum, I. S.; Tegner, J.; Piehl, F.; Jagodic, M.; Mellergard, J.; Altafini, C.; Ernerudh, J.; Jenmalm, M. C.; Nestor, C. E.; Kim, M.-S.; Gustafsson, M.

10.1101/599373 — bioinformatics — Posted on 2020-02-21

1098 The Development of Active Binocular Vision under Normal and Alternate Rearing Conditions

Klimmasch, L.; Schneider, J.; Lelais, A.; Shi, B. E.; Triesch, J.

10.1101/2020.02.20.957449 — neuroscience — Posted on 2020-02-21

1099 Causal modeling refutes Hockett's hypothesis that bite configuration affects human sound evolution

Tarasov, S.; Uyeda, J.

10.1101/2020.02.20.957407 — evolutionary biology — Posted on 2020-02-21

1100 A Multiscale and Comparative Model for Receptor Binding of 2019 Novel Coronavirus and the Implication of its Life Cycle in Host Cells

Su, Z.; Wu, Y.

10.1101/2020.02.20.958272 — biophysics — Posted on 2020-02-21

1101 Molecular mechanism of evolution and human infection with the novel coronavirus (2019-nCoV)

He, J.; Tao, H.; Yan, Y.; Huang, S.-Y.; Xiao, Y.

10.1101/2020.02.17.952903 — microbiology — Posted on 2020-02-21

1102 Succession of Bifidobacterium longum strains in response to the changing early-life nutritional environment reveals specific adaptations to distinct dietary substrates.

Kujawska, M.; Leanti La Rosa, S.; Pope, P. B.; Hoyles, L.; McCartney, A. L.; Hall, L. J.

10.1101/2020.02.20.957555 — microbiology — Posted on 2020-02-21

1103 Protection of Rhesus Macaque from SARS-Coronavirus challenge by recombinant adenovirus vaccine

Chen, Y.; Qin, C.; Wei, Q.; Li, R.; Gao, H.; Zhu, H.; Deng, W.; Bao, L.; Wei, T.

10.1101/2020.02.17.951939 — immunology — Posted on 2020-02-21

1104 Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

Qi, F.; Qian, S.; Zhang, S.; Zhang, Z.

10.1101/2020.02.16.951913 — immunology — Posted on 2020-02-21

1105 Limited evolution despite years of measurable viremia in a cART-treated seronegative HIV-1 positive individual

Fryer, H. R.; Raghwani, J.; van Marle, G.; Golubchi, T.; Grove, J.; Lythgoe, K.

10.1101/2020.02.20.957274 — evolutionary biology — Posted on 2020-02-21

1106 The crystal structure of heme d1 biosynthesis-associated small c-type cytochrome NirC reveals mixed oligomeric states in crystallo

Kluenemann, T.; Henke, S.; Blankenfeldt, W.

10.1101/2020.02.21.959056 — biochemistry — Posted on 2020-02-21

1107 Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM

Soufari, H.; Parrot, C.; Kuhn, L.; Waltz, F.; Hashem, Y.

10.1101/2020.02.21.959148 — molecular biology — Posted on 2020-02-21

1108 Crystal structure of Senecavirus A 3C protease

Meng, K.; Zhang, L.; Meng, G.

10.1101/2020.02.21.959106 — microbiology — Posted on 2020-02-21

1109 An asymmetry in the frequency and position of mitosis in the epiblast precedes gastrulation and suggests a role for mitotic rounding in cell delamination during primitive streak epithelial-mesenchymal transition.

Despin-Guitard, E.; Mathiah, N.; Stower, M.; Nahaboo, W.; Eski, E. S.; Singh, S. P.; Srinivas, S.; Migeotte, I.

10.1101/2020.02.21.959080 — developmental biology — Posted on 2020-02-21

1110 How do Dachsous and Fat polarise cells in the larval abdomen of Drosophila?

Casal, J.

10.1101/2020.02.21.959213 — developmental biology — Posted on 2020-02-21

1111 Phe-Gly Motifs Drive Fibrillization of TDP-43's Prion-Like Domain Droplets

Pantoja-Uceda, D.; Stuani, C.; Laurents, D. V.; McDermott, A. E.; Buratti, E.; Mompean, M.

10.1101/2020.02.20.957969 — biophysics — Posted on 2020-02-21

1112 Crystal structure of the human oxytocin receptor

Waltenspuehl, Y.; Schoeppe, J.; Ehrenmann, J.; Kummer, L.; Plueckthun, A.

10.1101/2020.02.21.958090 — biochemistry — Posted on 2020-02-21

1113 High-throughput behavioral screen in C. elegans reveals novel Parkinson disease drug candidates

Sohrabi, S.; Mor, D. E.; Kaletsky, R.; Keyes, W.; Murphy, C. T.

10.1101/2020.02.20.958751 — neuroscience — Posted on 2020-02-21

1114 Lutein restores synaptic functionality in a C. elegans model for mitochondrial complex I deficiency

Maglioni, S.; Schiavi, A.; Melcher, M.; Brinkmann, V.; Luo, Z.; Raimundo, N.; Laromaine, A.; Meyer, J.; Distelmaier, F.; Ventura, N.

10.1101/2020.02.20.957225 — neuroscience — Posted on 2020-02-21

1115 Alternative splicing coupled nonsense-mediated decay shapes the temperature-dependent transcriptome

Neumann, A.; Meinke, S.; Goldammer, G.; Strauch, M. D.; Schubert, D.; Timmermann, B.; Heyd, F.; Preussner, M.

10.1101/2020.02.19.956037 — molecular biology — Posted on 2020-02-21

1116 Structural and functional impact of the H5 hemagglutinin expression into a NDV vector vaccine backbone

Duchatel, V.; Steensels, M.; Verleysen, E.; Ingrao, F.; Mast, J.; Lambrecht, B.

10.1101/2020.02.19.957084 — microbiology — Posted on 2020-02-21

1117 Preserving Vascular Integrity Protects Mice Against Multidrug-Resistant Gram-Negative Bacterial Infection

Gebremariam, T.; Zhang, L.; Alkhazraji, S.; Gu, Y.; Youssef, E.; Tong, Z.; Kish-Trier, E.; Araujo, C. V.; Rich, B.; French, S. W.; Li, D.; Mueller, A.; Odelberg, S.; Zhu, W.; Ibrahim, A. S.

10.1101/2020.02.18.955518 — microbiology — Posted on 2020-02-21

1118 Boosting Toll-like receptor 4 signaling enhances the therapeutic outcome of antibiotic therapy in pneumococcal pneumonia

Casilag, F.; Franck, S.; Matarazzo, L.; Figeac, M.; Michelet, R.; Kloft, C.; Carnoy, C.; Sirard, J.-C.

10.1101/2020.02.18.955500 — microbiology — Posted on 2020-02-21

1119 Novelty-seeking impairment in addiction

Cogliati Dezza, I.; Noel, X.; Cleeremans, A.; Yu, A.

10.1101/2020.02.19.955989 — bioinformatics — Posted on 2020-02-21

1120 Genetic Variants and Functional Pathways Associated with Resilience to Alzheimer's Disease

Dumitrescu, L.; Mahoney, E. R.; Mukherjee, S.; Lee, M. L.; Bush, W. S.; Engelman, C. D.; Lu, Q.; Fardo, D. W.; Trittschuh, E. H.; Mez, J.; Kaczorowski, C.; Hernandez Saucedo, H.; Widaman, K. F.; Buckley, R.; Properzi, M.; Mormina, E.; Yang, H.-S.; Harrison, T.; Hedden, T.; Nho, K.; Andrews, S. J.; Tommet, D.; Hadad, N.; Sanders, R. E.; Ruderfer, D. M.; Gifford, K. A.; Moore, A. M.; Cambronero, F.; Zhong, X.; Raghavan, N. S.; Vardarajan, B.; The Alzheimer's Disease Neuroimaging Initiative (ADNI), ; Alzheimer's Disease Genetics Consortium (ADGC), ; A4 Study Team, ; Pericak-Vance, M. A.; Farre

10.1101/2020.02.19.954651 — genetics — Posted on 2020-02-21

1121 Disputing space-based biases in unilateral complex regional pain syndrome

Halicka, M.; Vitterso, A. D.; McCullough, H.; Goebel, A.; Heelas, L.; Proulx, M. J.; Bultitude, J. H.

10.1101/2020.01.02.893263 — neuroscience — Posted on 2020-02-21

1122 Analysis of Circulating Exosomes Reveals a Peripheral Signature of Astrocytic Pathology in Schizophrenia

Ranganathan, M.; Rahman, M.; Ganesh, S.; D'Souza, D. C.; Skosnik, P. D.; Radhakrishnan, R.; Pathania, S.; Mohanakumar, T.

10.1101/2020.02.18.955013 — neuroscience — Posted on 2020-02-21

1123 Sexual selection does not increase the rate of compensatory adaptation to a mutation influencing a secondary sexual trait in Drosophila melanogaster

Chandler, C. H.; Mammel, A.; Dworkin, I.

10.1101/686741 — evolutionary biology — Posted on 2020-02-21

1124 Keratins and Plakin family cytolinker proteins control the length of epithelial microridge protrusions

Inaba, Y.; Chauhan, V.; van Loon, A. P.; Choudhury, L. S.; Sagasti, A.

10.1101/2020.02.18.954933 — cell biology — Posted on 2020-02-21

1125 Prevalence and global distribution of blaKPC-2 and blaNDM-1 genes in Klebsiella Pneumoniae

Xiufeng, Z.; Fangping, L.; Xiaohua, L.; Lisha, M.; Yixing, L.; Awan, F.; Weibiao, L.; Zhenling, Z.

10.1101/2020.02.18.955211 — bioinformatics — Posted on 2020-02-21

1126 Regulatory DNA keyholes enable specific and persistent multi-gene expression programs in primary T cells without genome modification

Wilken, M. S.; Ciarlo, C.; Pearl, J.; Bloom, J.; Schanzer, E.; Liao, H.; Boyken, S. E.; Van Biber, B.; Queitsch, K.; Heberlein, G.; Federation, A.; Acosta, R.; Vong, S.; Otterman, E.; Dunn, D.; Wang, H.; Zrazhevskey, P.; Nandakumar, V.; Bates, D.; Sandstrom, R.; Chen, Z.; Urnov, F. D.; Baker, D.; Funnell, A.; Green, S.; Stamatoyannopoulos, J. A.

10.1101/2020.02.19.956730 — synthetic biology — Posted on 2020-02-20

1127 Towards Practical and Robust DNA-based Data Archiving by Codec System Named 'Yin-Yang'

Ping, Z.; Chen, S.; Zhou, G.; Huang, X.; Zhu, S.; Chai, C.; Zhang, H.; Lee, H. H.; Chiu, T.-Y.; Chen, T.; Yang, H.; Xu, X.; Church, G. M.; Shen, Y.

10.1101/829721 — synthetic biology — Posted on 2020-02-20

1128 Host-induced gene silencing involves transfer of dsRNA-derived siRNA via extracellular vesicles

Koch, A.; Schlemmer, T.; Hoefle, L.; Werner, B.; Preusser, C.; Hardt, M.; Moebus, A.; Biedenkopf, D.; Claar, M.; Perlet, C.; Jelonek, L.; Goesmann, A.; Garikapati, V.; Spengler, B.; Busche, T.; Kalinowski, J.; Kogel, K.-H.

10.1101/2020.02.12.945154 — plant biology — Posted on 2020-02-21

1129 LncRNA Gm12664 up-regulates CAV1 expression to promote hepatocellular lipid accumulation by sponging miR-295-5p

xu, f.; Wang, L.; CHEN, L.; Zhang, Q.; xin, n. l.

10.1101/2020.02.15.951095 — molecular biology — Posted on 2020-02-20

1130 Multi-omic surveillance of Escherichia coli and Klebsiella spp. in hospital sink drains and patients

10.1101/2020.02.19.952366 — microbiology — Posted on 2020-02-21

1131 Diversity of culturable actinobacteria producing protease inhibitors from the intertidal zones of Maharashtra, India

Shintre, N. A.; Tamhane, V. A.; Baig, U.; Pund, A.; Patwardhan, R.; Deshpande, N. M.

10.1101/2020.02.14.949438 — microbiology — Posted on 2020-02-21

1132 Towards an evolutionarily appropriate null model: jointly inferring demography and purifying selection

Johri, P.; Charlesworth, B.; Jensen, J. D.

10.1101/2019.12.18.881516 — evolutionary biology — Posted on 2020-02-21

1133 Inhibiting endoplasmic reticulum stress decreases tumor burden in a mouse model for hepatocellular carcinoma.

Pavlovic, N.; Calitz, C.; Thanapirom, K.; Mazza, G.; Rombouts, K.; Gerwins, P.; Heindryckx, F.

10.1101/826453 — cancer biology — Posted on 2020-02-20

1134 Rethinking success, integrity, and culture in research (part 1) -- A multi-actor qualitative study on success in science

Aubert Bonn, N.; Pinxten, W.

10.1101/2020.02.12.945733 — scientific communication and education — Posted on 2020-02-20

1135 High-temperature live-cell imaging of cytokinesis, cell motility and cell-cell adhesion in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius

Charles-Orszag, A.; Lord, S. J.; Mullins, D.

10.1101/2020.02.16.951772 — cell biology — Posted on 2020-02-20

1136 The a-isoform of VEGFA165 is a Significantly Stronger Activator of Human Retinal Endothelial Cells compared to the b-isoform

Dailey, W.; Schunemann, R.; Yang, F.; Moore, M.; Knapp, A.; Chen, P.; Deshpande, M.; Metcalf, B.; Tompkins, Q.; Guzman, A. E.; Felisky, J.; Mitton, K. P.

10.1101/2019.12.12.871947 — cell biology — Posted on 2020-02-20

1137 Kinetic fingerprints differentiate anti-Aβ therapies

10.1101/815308 — biophysics — Posted on 2020-02-20

1138 μCB-seq: Microfluidic cell barcoding and sequencing for high-resolution imaging and sequencing of single cells

Chen, T. N.; Gupta, A. N.; Zalavadia, M. D.; Streets, A.

10.1101/2020.02.18.954974 — bioengineering — Posted on 2020-02-20

1139 Metabolic modelling of the C3-CAM continuum revealed the establishment of a starch/sugar-malate cycle in CAM evolution

Tay, I. Y. Y.; Odang, K. B.; Cheung, C. Y. M.

10.1101/2019.12.16.877621 — biochemistry — Posted on 2020-02-20

1140 Diversification of perceptual mechanisms underlying preserved multisensory behaviour in healthy aging

Park, H.; Nannt, J.; Kayser, C.

10.1101/2020.02.12.945949 — neuroscience — Posted on 2020-02-20

1141 β-catenin-Mediated Wnt Signal Transduction Proceeds Through an Endocytosis-Independent Mechanism

Rim, E. Y.; Kinney, L. K.; Nusse, R.

10.1101/2020.02.13.948380 — cell biology — Posted on 2020-02-20

1142 Local intracerebral Inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo.

Le Reste, P.-J.; Pineau, R.; Voutetakis, K.; Samal, J.; Jegou, G.; Lhomond, S.; Gorman, A. M.; Samali, A.; Patterson, J. B.; Zeng, Q.; Pandit, A.; AUBRY, M.; Soriano, N.; Etcheverry, A.; Mosser, J.; Avril, T.; chevet, e.

10.1101/841296 — cancer biology — Posted on 2020-02-20

1143 Machine learning using intrinsic genomic signatures for rapid classification of novel pathogens: COVID-19 case study

Randhawa, G. S.; Soltysiak, M. P. M.; El Roz, H.; de Souza, C. P. E.; Hill, K. A.; Kari, L.

10.1101/2020.02.03.932350 — bioinformatics — Posted on 2020-02-20

1144 IRESbase: a Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites

Zhao, J.; Li, Y.; Wang, C.; Zhang, H.; Zhang, H.; Jiang, B.; Guo, X.; Song, X.

10.1101/2020.01.15.894592 — bioinformatics — Posted on 2020-02-20

1145 Dopamine transporter trafficking and Rit2 GTPase: In vivo impact and mechanism of action

Fagan, R. R.; Kearney, P. J.; Sweeney, C. G.; Luethi, D.; Schoot Uiterkamp, F. E.; Schicker, K.; O'Connor, L. C.; Sitte, H. H.; Melikian, H. E.

10.1101/712448 — neuroscience — Posted on 2020-02-20

1146 Neuropeptide Y expression defines a novel class of GABAergic projection neuron in the inferior colliculus

Silveira, M. A.; Anair, J. D.; Beebe, N. L.; Mirjalili, P.; Schofield, B. R.; Roberts, M. T.

10.1101/812388 — neuroscience — Posted on 2020-02-20

1147 A validation framework for neuroimaging software: the case of population receptive fields

Lerma-Usabiaga, G.; Benson, N.; Winawer, J.; Wandell, B. A.

10.1101/2020.01.07.897991 — neuroscience — Posted on 2020-02-20

1148 The RNA-binding proteins CELF1 and ELAVL1 cooperatively control alternative splicing

David, G.; Reboutier, D.; Deschamps, S.; Mereau, A.; Taylor, W.; Padilla-Parra, S.; Tramier, M.; Audic, Y.; Paillard, L.

10.1101/373704 — molecular biology — Posted on 2020-02-20

1149 An alternative replication niche for Listeria monocytogenes revealed by fluorescent tagging of bacterial secreted effectors

Peron Cane, C.; Leblanc, J.; Wingertsmann, L.; Fernandez, J.-C.; Gautier, A.; Desprat, N.; Lebreton, A.

10.1101/2019.12.23.886689 — microbiology — Posted on 2020-02-20

1150 Genome-wide Association Study of Pediatric Obsessive-Compulsive Traits: Shared Genetic Risk between Traits and Disorder

Burton, C. L.; Lemire, M.; Xiao, B.; Corfield, E. C.; Erdman, L.; Bralten, J.; Poelmans, G.; Yu, D.; Shaheen, S.-M.; Goodale, T.; OCD Working Group of the Psychiatric Genomics Consortium, ; Soreni, N.; Hanna, G. L.; Fitzgerald, K. D.; Rosenberg, D.; Nestadt, G.; Paterson, A. D.; Strug, L.; Schachar, R. J.; Crosbie, J.; Arnold, P. D.

10.1101/858241 — genomics — Posted on 2020-02-20

1151 Multivariate Analyses of Codon Usage in 2019 Novel Coronavirus on the Genomic Landscape of Betacoronavirus

Gu, H.; Chu, D. K. W.; Peiris, J. S. M.; Poon, L. L. M.

10.1101/2020.02.15.950568 — evolutionary biology — Posted on 2020-02-20

1152 GeneRax: A tool for species tree-aware maximum likelihood based gene tree inference under gene duplication, transfer, and loss.

Morel, B.; Kozlov, A.; Stamatakis, A.; Szöllosi, G.

10.1101/779066 — bioinformatics — Posted on 2020-02-20

1153 Genomic characterization of the non-O1/non-O139 Vibrio cholerae strain that caused a gastroenteritis outbreak in Santiago, Chile, 2018

Arteaga, M.; Velasco, J.; Rodriguez, S.; Vidal, M.; Arellano, C.; Silva, F.; Carreno, L. J.; Vidal, R. M.; Montero, D. A.

10.1101/835090 — microbiology — Posted on 2020-02-20

1154 Evaluation of Antimicrobial, Antioxidant, Total Phenolic, Total Flavonoids, Metal Content and Proximate Potential of Solanum xanthocarpum L. (Solanaceae)

AZHAR, N.; Khan, M. Q.; Bibi, A.; Shoaib, M.; Mumtaz, S.; Batool, T.; Ashraf, S.; Ijaz, S.; Firdous, S.; Sharif, F.

10.1101/2020.02.20.957381 — plant biology — Posted on 2020-02-20

1155 Automated identification of multinucleated germ cells with U-Net

Bell, S.; Zsom, A.; Conley, J.; Spade, D.

10.1101/2020.02.20.957332 — pharmacology and toxicology — Posted on 2020-02-20

1156 Novel phenotype of Wolbachia strain wPip in Aedes aegypti challenges assumptions on mechanisms of Wolbachia-mediated dengue virusinhibition .

Fraser, J. E.; O'Donnell, T. B.; Duyvestyn, J. M.; O'Neill, S. L.; Simmons, C. P.; Flores, H. A.

10.1101/2020.02.20.957423 — microbiology — Posted on 2020-02-20

1157 Allergen Extraction: Factors Influencing the Yield, Allergenicity and Sensitivity of Immunoassays

Soares, J. R. A.; Pereira e Silva, A.; Oliveira, A. L. d. S.; Guimaraes, I. M.; Faccini, C. R. J. d. N.; Mattos, E. B. d. A.; Rodrigues, S. K. P. M.; Marmello, B. O.; Teixeira, G. A. P. B.

10.1101/2020.02.20.957373 — immunology — Posted on 2020-02-20

1158 Characterization of a regulatory T cells meta-signature identifies the pro-enkephalin gene as a novel marker in mice

Aubert, N.; Salomon, B.; Marodon, G.

10.1101/638072 — immunology — Posted on 2020-02-20

1159 Tree bark scrape fungus: A potential source of laccase for application in bioremediation of non-textile dyes

Bhamare, H. M.; Sayyed, R. Z.; Marraiki, M.; Elgorban, A.; Syed, A.; Enshasy, H.

10.1101/2020.02.20.957365 — biochemistry — Posted on 2020-02-20

1160 Characterization of the dimeric interactions of dimeric and tetrameric conformations of the PvNV protrusion-domain using a mixed DFT/QTAIM approach

Astani, E. K.; Chen, N.-C.; Huang, Y.-C.; Ersali, S.; Lin, P.-J.; Guan, H.-H.; Lin, C.-C.; Chuankhayan, P.; Chen, C.-J.

10.1101/2020.02.20.957316 — biochemistry — Posted on 2020-02-20

1161 The Drosophila TART transposon manipulates the piRNA pathway as a counter-defense strategy to limit host silencing

Ellison, C.; Kagda, M. S.; Cao, W.

10.1101/2020.02.20.957324 — genomics — Posted on 2020-02-20

1162 Removal modelling in ecology

Rodriguez de Rivera, O.; McCrea, R.

10.1101/2020.02.20.957357 — ecology — Posted on 2020-02-20

1163 Neuraminidase antigenic drift of influenza A virus H3N2 clade 3c.2a viruses alters virus replication, enzymatic activity and inhibitory antibody binding

Powell, H.; Pekosz, A.

10.1101/2020.02.20.957399 — microbiology — Posted on 2020-02-20

1164 Identification of novel mitochondrial and mitochondrial related genetic loci associated with exercise response in the Gene SMART study

Harvey, N. R.; Voisin, S.; Lea, R. A.; Yan, X.; Benton, M. C.; Papadimitriou, I. D.; Jacques, M.; Haupt, L. M.; Ashton, K. J.; Eynon, N.; Griffiths, L. R.

10.1101/2020.02.20.957340 — genetics — Posted on 2020-02-20

1165 Slow Axonal Transport and Presynaptic Targeting of Clathrin Packets

Ganguly, A.; Wernert, F.; Phan, S.; BOASSA, D.; Das, U.; Sharma, R.; Caillol, G.; Han, X.; Yates, J. R.; Ellisman, M.; Leterrier, C.; Roy, S.

10.1101/2020.02.20.958140 — neuroscience — Posted on 2020-02-20

1166 Characterizing Sleep-Wake Circadian Rhythm Consolidation in Early Childhood and Its Association with Motor Development Using Actigraphy

Li, X.; Kane, M.; Zhang, Y.; Sun, W.; Song, Y.; Dong, S.; Lin, Q.; Zhu, Q.; Jiang, F.; Zhao, H.

10.1101/2020.02.20.957076 — neuroscience — Posted on 2020-02-20

1167 Enhancing GABAergic Tone in the Rostral Nucleus of the Solitary Tract Reconfigures Sensorimotor Neural Activity

Sammons, J. D.; Bass, C. E.; Victor, J. D.; Di Lorenzo, P. M.

10.1101/2020.02.20.958199 — neuroscience — Posted on 2020-02-20

1168 Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level

Imamura, H.; Jara, M.; Monsieurs, P.; Sanders, M.; Maes, I.; Vanaerschot, M.; Berriman, M.; Cotton, J. A.; Dujardin, J.-C.; Domagalska, M. A.

10.1101/2020.02.20.957621 — microbiology — Posted on 2020-02-20

1169 Single cell transcriptional characterization of human megakaryocyte lineage commitment and maturation

Choudry, F. A.; Otzen Bagger, F.; Macaulay, I. C.; Farrow, S.; Burden, F.; Kempster, C.; McKinney, H.; Olsen, L. R.; Huang, N.; Downes, K.; Voet, T.; Uppal, R.; Martin, J.; Mathur, A.; Ouwehand, W. h.; Laurenti, E.; Teichmann, S.; Frontini, M.

10.1101/2020.02.20.957936 — cell biology — Posted on 2020-02-20

1170 CK1 Delta Is an mRNA Cap-Associated Protein That Drives Translation Initiation and Tumor Growth

Pal, I.; Grilo, A. M. S.; Berchowitz, L. E.; DasSharma, S.; Mundi, P. S.; Ali, A. M.; Martin, M. L.; Safari, M.; Scotto, L.; Malkovskiy, E.; Sawas, A.; Mukherjee, S.; O'Connor, O. A.; Jovanovic, M.; Deng, C.

10.1101/2020.02.20.955229 — cancer biology — Posted on 2020-02-20

1171 The helix bundle domain of primase RepB' is required for dinucleotide formation and extension

Banchenko, S.; Weise, C.; Lanka, E.; Saenger, W.; Geibel, S.

10.1101/2020.02.20.955914 — biochemistry — Posted on 2020-02-20

1172 Resistance to decitabine and 5-azacytidine emerges from adaptive responses of the pyrimidine metabolism network

Gu, X.; Tohme, R.; Tomlinson, B.; Hasipek, M.; Durkin, L.; Schuerger, C.; Zidan, A. M.; Radivoyevitch, T.; Hong, C.; Carraway, H.; Hamilton, B.; Sobecks, R.; Jha, B. K.; Hsi, E. D.; Maciejewski, J.; Saunthararajah, Y.

10.1101/2020.02.20.958405 — cancer biology — Posted on 2020-02-20

1173 Annexin A4 trimers are recruited by high membrane curvatures in Giant Plasma Membrane Vesicles

Florentsen, C. D.; Kamp-Sonne, A.; Pescador, G. M.; Pezeshkian, W.; Hakami Zanjani, A. A.; Khandelia, H.; Nylandsted, J.; Bendix, P. M.

10.1101/2020.02.20.957183 — biophysics — Posted on 2020-02-20

1174 Proteome overabundance enables respiration but limitation onsets carbon overflow

Kumar, R.; Lahtvee, P.-J.

10.1101/2020.02.20.957662 — systems biology — Posted on 2020-02-20

1175 Systemic Bone Loss Following Myocardial Infarction in Mice is Mitigated by Treatment with a β3 Adrenergic Receptor Antagonist

Tjandra, P. M.; Paralkar, M. P.; Osipov, B.; Chen, Y.-J.; Zhao, F.; Ripplinger, C. M.; Christiansen, B. A.

10.1101/2020.02.20.958116 — physiology — Posted on 2020-02-20

1176 Theory of Neuronal Perturbome: Linking Connectivity to Coding via Perturbations

Sadeh, S.; Clopath, C.

10.1101/2020.02.20.954222 — neuroscience — Posted on 2020-02-20

1177 Endoplasmic reticulum (ER) lumenal indicators in Drosophila reveal effects of HSP-related mutations on ER calcium dynamics

Oliva, M. K.; Perez-Moreno, J.-J.; O'Shaughnessy, J.; Wardill, T. J.; O'Kane, C. J.

10.1101/2020.02.20.957696 — neuroscience — Posted on 2020-02-20

1178 Altered synaptic plasticity and central pattern generator dysfunction in a Drosophila model of PNKD3 paroxysmal dyskinesia

Lowe, S.; Kratschmer, P.; Jepson, J. E. C.

10.1101/2020.02.20.957639 — neuroscience — Posted on 2020-02-20

1179 Deconvolving nuclesome binding energy from experimental errors

Heron, M.; Soeding, J.

10.1101/2020.02.20.957878 — molecular biology — Posted on 2020-02-20

1180 Modulation of bacterial multicellularity via spatiotemporal polysaccharide secretion

Islam, S. T.; Vergara Alvarez, I.; Saïdi, F.; Giuseppi, A.; Vinogradov, E.; Morrone, C.; Brasseur, G.; Sharma, G.; Benarouche, A.; Bridot, J.-L.; Ravicoularamin, G.; Cagna, A.; Gauthier, C.; Singer, M.; Fierobe, H.-P.; Mignot, T.; Mauriello, E. M. F.

10.1101/2020.02.20.957654 — microbiology — Posted on 2020-02-20

1181 The evolution of bacterial shape complexity by a curvature-inducing module

Martin, N. R.; Blackman, E.; Bratton, B. P.; Bartlett, T. M.; Gitai, Z.

10.1101/2020.02.20.954503 — microbiology — Posted on 2020-02-20

1182 Comprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes

Ravenhill, B. J.; Soday, L.; Houghton, J.; Antrobus, R.; Weekes, M. P.

10.1101/2020.02.20.958009 — immunology — Posted on 2020-02-20

1183 Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration

Calero-Cuenca, F. J.; Osorio, D. S.; Sridhara, S. C.; Jiao, Y.; Diaz, J.; Carvalho-Marques, S.; Cadot, B.; Gomes, E. R.

10.1101/2020.02.20.957761 — cell biology — Posted on 2020-02-20

1184 Improving Metagenomic Classification using Discriminative k-mers from Sequencing Data

Storato, D.; Comin, M.

10.1101/2020.02.20.957308 — bioinformatics — Posted on 2020-02-20

1185 Two distinct types of eye-head coupling in freely moving mice

Meyer, A. F.; O'Keefe, J.; Poort, J.

10.1101/2020.02.20.957712 — animal behavior and cognition — Posted on 2020-02-20

1186 Genome Wide Analysis of Dinucleotide Distribution along the Genomes of Species and its Biological Implication

Cai, Z.; Liu, S.; Xue, Y.; Quan, H.; Zhang, L.; Gao, Y. Q.

10.1101/2020.02.20.957142 — evolutionary biology — Posted on 2020-02-20

1187 ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in glioblastoma

Vue, T. Y.; Kollipara, R.; Borromeo, M. D.; Smith, T.; Mashimo, T.; Burns, D. K.; Bachoo, R. M.; Johnson, J. E.

10.1101/2020.02.20.958132 — cancer biology — Posted on 2020-02-20

1188 Low Cost Metabolic Fuel Sensor for On-Demand Personal Health and Fitness Tracking

Candell, L. M.; Hoyt, R. W.; Mahan, J. M.; Siegel, A. M.; Standley, R. M.; Thompson, K. J.; Shaw, G. A.

10.1101/2020.02.20.958264 — bioengineering — Posted on 2020-02-20

1189 Phylogeny of the stink bug tribe Chlorocorini (Heteroptera, Pentatomidae) based on DNA and morphological data

Genevcius, B. C.; Greve, C.; Koehler, S.; Simmons, R. B.; Rider, D. A.; Grazia, J.; Schwertner, C. F.

10.1101/2020.02.20.957811 — zoology — Posted on 2020-02-20

1190 The fish body functions as an airfoil: surface pressures generate thrust during carangiform locomotion

Lucas, K. N.; Lauder, G. V.; Tytell, E. D.

10.1101/2020.02.20.958389 — physiology — Posted on 2020-02-20

1191 Oxidative Modifications of Parkin Underlie its Selective Neuroprotection in Adult Human Brain

Tokarew, J. M.; El-Kodsi, D. N.; Lengacher, N. A.; Fehr, T. K.; Nguyen, A. P.; O'Nuallain, B.; Jin, M.; Khan, J. M.; Ng, A. C.-H.; Li, J.; Jiang, Q.; Zhang, M.; Wang, L.; Sengupta, R.; Barber, K. R.; Tran, A.; Zandee, S.; Dong, X.; Scherzer, C. R.; Prat, A.; Tsai, E.; Takanashi, M.; Hattori, N.; Chan, J. A.; West, A. B.; Holmgren, A.; Puente, L.; Shaw, G. S.; Toth, G.; Woulfe, J. M.; Taylor, P.; Tomlinson, J. J.; Schlossmacher, M. G.

10.1101/2020.02.19.953034 — neuroscience — Posted on 2020-02-20

1192 A knock-in Drosophila model supports a conserved link between potassium channelopathy and involuntary movement

Kratschmer, P.; Buhl, E.; Chen, K.-F.; Lowe, S.; Kullmann, D. M.; Hodge, J. J. L.; Jepson, J. E. C.

10.1101/2020.02.20.957571 — neuroscience — Posted on 2020-02-20

1193 Kinfitr - an open source tool for reproducible PET modelling: validation and evaluation of test-retest reliability

Tjerkaski, J.; Cervenka, S.; Farde, L.; Matheson, G. J.

10.1101/2020.02.20.957738 — neuroscience — Posted on 2020-02-20

1194 Control of Systemic Iron Homeostasis by the 3' Iron-Responsive Element of Divalent Metal Transporter 1 in Mice.

Tybil, E.; Gunshin, H.; Gupta, S.; Barrientos, T.; Bonadonna, M.; Nos, F. C.; Palais, G.; Karim, Z.; Sanchez, M.; Andrews, N. C.; galy, b.

10.1101/2020.02.20.957779 — molecular biology — Posted on 2020-02-20

1195 Tasting the differences: microbiota analysis of different insect-based novel food

Frigerio, J.; Agostinetto, G.; Galimberti, A.; De Mattia, F.; Labra, M.; Bruno, A.

10.1101/2020.02.20.957845 — microbiology — Posted on 2020-02-20

1196 Commensal oral Rothia mucilaginosa produces enterobactin - a metal chelating siderophore

Uranga, C.; Arroyo, P.; Duggan, B. M.; Gerwick, W. H.; Edlund, A.

10.1101/2020.02.20.956391 — microbiology — Posted on 2020-02-20

1197 Tissue-specific profiling reveals distinctive regulatory architectures for ubiquitous, germline and somatic genes

Serizay, J.; Dong, Y.; Janes, J.; Chesney, M. A.; Cerrato, C.; Ahringer, J.

10.1101/2020.02.20.958579 — genomics — Posted on 2020-02-20

1198 New pathogenic variants and insights into pathogenic mechanisms in GRK1-related Oguchi disease.

Poulter, J. A.; Gravett, M.; Taylor, R. L.; Fujinami, K.; De Zaeytijd, J.; Bellingham, J.; Hayashi, T.; Kondo, M.; Donnelly, D.; Toomes, C.; Ali, M.; UK Inherited Retinal Disease Consortium, ; Genomics England Research Consortium, ; De Baere, E.; Leroy, B. P.; Davies, N. P.; Webster, A. R.; Mahroo, O. A.; Arno, G.; Black, G. C.; McKibbin, M.; Harris, S. A.; Khan, K. N.; Inglehearn, C. F.

10.1101/2020.02.20.936880 — genetics — Posted on 2020-02-20

1199 Groups Of Species Responding To Soil And Light In The Cerrado

Tolentino, G.; Maguas, C.; Magnago, L.; Buttschardt, T.; Meira-Neto, J. A. A.

10.1101/2020.02.20.955955 — ecology — Posted on 2020-02-20

1200 Notch Signaling Commits Mesoderm to the Cardiac Lineage

Bardot, E. S.; Jadhav, B.; Wickramasinghe, N.; Rezza, A.; Rendl, M.; Sharp, A. J.; Dubois, N. C.

10.1101/2020.02.20.958348 — developmental biology — Posted on 2020-02-20

1201 Quantitative analyses reveal extracellular dynamics of Wnt ligands in Xenopus embryos

Mii, Y.; Nakazato, K.; Pack, C.-G.; Sako, Y.; Mochizuki, A.; Takada, S.; Taira, M.

10.1101/2020.02.20.957860 — developmental biology — Posted on 2020-02-20

1202 PAG1 directs SRC-family kinase intracellular localization to mediate receptor tyrosine kinase-induced differentiation

Foltz, L.; Palacios-Moreno, J.; Mayfield, M.; Kinch, S.; Dillon, J.; Syrenne, J.; Levy, T.; Grimes, M. L.

10.1101/2020.02.20.958496 — cell biology — Posted on 2020-02-20

1203 USP29 is a novel non-canonical Hypoxia Inducible Factor-α activator

Schober, A. S.; Martin-Barros, I.; Martin-Mateos, T.; Perez-Andres, E.; Carlevaris, O.; Pozo, S.; Cortazar, A. R.; Aransay, A. M.; Carracedo, A.; Mayor, U.; See, V.; Berra, E.

10.1101/2020.02.20.957688 — cell biology — Posted on 2020-02-20

1204 Classification of multigene families of African swine fever viruses

Zhu, Z.; Peng, Y.

10.1101/2020.02.20.957290 — bioinformatics — Posted on 2020-02-20

1205 Improved daylight vision following AAV-mediated expression of R9AP in murine rod photoreceptors

Nishiguchi, K. M.; Fujita, K.; Cristante, E.; Bainbridge, J. W.; Douglas, R. H.; Nakazawa, T.; Smith, A.; Ali, R. R.

10.1101/2020.02.19.955765 — bioengineering — Posted on 2020-02-20

1206 A Multi-Scale Computational Model of Excitotoxic Loss of Dopaminergic Cells in Parkinson's Disease

Muddapu, V. R.; Chakravarthy, V. S.

10.1101/2020.02.20.957704 — neuroscience — Posted on 2020-02-20

1207 Large-scale dissociations between views of objects, scenes, and reachable-scale environments in visual cortex

Josephs, E. L.; Konkle, T.

10.1101/2020.02.20.956441 — neuroscience — Posted on 2020-02-20

1208 Selective and controlled myelin formation by individual interfascicular oligodendrocytes in the mouse corpus callosum

Tanaka, T.; Ohno, N.; Osanai, Y.; Saitoh, S.; Thai, T. Q.; Nishimura, K.; Shinjo, T.; Takemura, S.; Tatsumi, K.; Wanaka, A.

10.1101/2020.02.20.957522 — neuroscience — Posted on 2020-02-20

1209 Cerebellar theta and beta noninvasive stimulation rhythms differentially influence episodic memory versus language

Dave, S.; VanHaerents, S.; Voss, J.

10.1101/2020.02.20.958397 — neuroscience — Posted on 2020-02-20

1210 A family of contact-dependent nuclease effectors contain an exchangeable, species-identifying domain

Sirias, D.; Utter, D. R.; Gibbs, K. A.

10.1101/2020.02.20.956912 — microbiology — Posted on 2020-02-20

1211 Evolution of multicellularity by collective integration of spatial information

Colizzi, E. S.; Vroomans, R. M. A.; Merks, R. M. H.

10.1101/2020.02.20.957647 — evolutionary biology — Posted on 2020-02-20

1212 Mining Pathway Associations from Networks of Mutual Exclusivity Interactions

Liany, H.; Lin, Y.; Jeyasekharan, A.; Rajan, V.

10.1101/2020.02.20.957241 — bioinformatics — Posted on 2020-02-20

1213 A New World begomovirus infecting Grapevine

Debat, H.; Zavallo, D.; Moyano, S.; Luna, F.; Asurmendi, S.; Gomez-Talquenca, S.

10.1101/2020.02.20.957548 — microbiology — Posted on 2020-02-20

1214 Tracing the origin of a new organ by inferring the genetic basis of rumen evolution

Pan, X.; Wang, Y.; Li, Z.; Chen, X.; Heller, R.; Wang, N.; Zhao, C.; Cai, Y.; Xu, H.; Li, S.; Li, M.; Li, C.; Hu, S.; Li, H.; Wang, K.; Chen, L.; Wei, B.; Zheng, Z.; Fu, W.; Yang, Y.; Zhang, T.; Hou, Z.; Yan, Y.; Lv, X.; Sun, W.; Li, X.; Huang, S.; Liu, L.; Mao, S.; Liu, W.; Hua, J.; Li, Z.; Zhang, G.; Chen, Y.; Wang, X.; Qiu, Q.; Dalrymple, B. P.; Wang, W.; Jiang, Y.

10.1101/2020.02.19.955872 — evolutionary biology — Posted on 2020-02-20

1215 Anomalous invasion dynamics due to dispersal polymorphism and dispersal-reproduction trade-offs

Keenan, V. A.; Cornell, S. J.

10.1101/2020.02.19.956425 — ecology — Posted on 2020-02-20

1216 Bidirectional control of fear memories by the cerebellum through the ventrolateral periaqueductal grey

Frontera, J. L.; Baba Aïssa, H.; Sala, R. W.; Mailhes-Hamon, C.; Georgescu, I. A.; Lena, C.; Popa, D.

10.1101/2020.02.19.956375 — neuroscience — Posted on 2020-02-20

1217 Continuous regimens of cortico-motor integration calibrate levels of arousal during emergence from anesthesia

Gao, S.; Calderon, D. P.

10.1101/2020.02.19.956789 — neuroscience — Posted on 2020-02-20

1218 Emergence of Visual Center-Periphery Spatial Organization in Deep Convolutional Neural Networks

Mohsenzadeh, Y.; Mullin, C.; Lahner, B.; Oliva, A.

10.1101/2020.02.19.956748 — neuroscience — Posted on 2020-02-20

1219 Functional reorganization of visual processing following long-term adaptation to optical defects

Barbot, A.; Park, W.-J.; Zhang, R.-Y.; Huxlin, K. R.; Tadin, D.; Yoon, G.

10.1101/2020.02.19.956219 — neuroscience — Posted on 2020-02-20

1220 Deep sampling and pooled amplicon sequencing reveals hidden genic variation in heterogeneous rye accessions

Hawliczek, A.; Bolibok, L.; Tofil, K.; Borzecka, E.; Jankowicz-Cieslak, J.; Gawronski, P.; Kral, A.; Till, B. J.; Bolibok-Bragoszewska, H.

10.1101/2020.02.20.958181 — genomics — Posted on 2020-02-20

1221 Overlapping Pathogenic Signalling Pathways and Biomarkers in Preeclampsia and Cardiovascular Disease

Suvakov, S.; Bonner, E.; Nikolic, V.; Jerotic, D.; Simic, T.; Garovic, V.; Lopez Campos, G.; McClements, L.

10.1101/2020.02.18.955260 — bioinformatics — Posted on 2020-02-20

1222 Interpreting Deep Neural Networks Beyond Attribution Methods: Quantifying Global Importance of Genomic Features

Koo, P. K.; Ploenzke, M.

10.1101/2020.02.19.956896 — bioinformatics — Posted on 2020-02-20

1223 Common and separable neural alterations in substance use disorders: evidence from coordinate-based meta-analyses of functional neuroimaging studies in human

Klugah-Brown, B.; Di, X.; Zweerings, J.; Mathiak, K.; Becker, B.; Biswal, B. B.

10.1101/2020.02.19.956755 — neuroscience — Posted on 2020-02-20

1224 The Drosophila seminal Sex Peptide can associate with rival as well as own sperm and provide function for SP in polyandrous females

Misra, S.; Wolfner, M. F.

10.1101/2020.02.20.958108 — evolutionary biology — Posted on 2020-02-20

1225 Modeling microbial cross-feeding at intermediate scale portrays community dynamics and species coexistence

Liao, C.; Wang, T.; Maslov, S.; Xavier, J.

10.1101/2020.02.19.956383 — ecology — Posted on 2020-02-20

1226 Full cell infiltration and thick tissue formation in vivo in tailored electrospun scaffolds

Zonderland, J.; Rezzola, S.; Gomes, D. B.; Camarero Espinosa, S.; Ferreira Lourenco, A. H.; Serafim, A.; Stancu, I. C.; Koper, D.; Liu, H.; Habibovic, P.; Kessler, P.; Peters, M.; Emans, P.; Bouvy, N.; Wieringa, P.; Moroni, L.

10.1101/2020.02.19.955948 — bioengineering — Posted on 2020-02-20

1227 A causal role for estradiol in human reinforcement learning

Veselic, S.; Jocham, G.; Gausterer, C.; Wagner, B.; Ressler, M.; Lanzenberger, R.; Lamm, C.; Eisenegger, C.; Vermeer, A. L.

10.1101/2020.02.18.954982 — neuroscience — Posted on 2020-02-20

1228 Visual predictions, neural oscillations and Newtonian physics.

Saurels, B. W.; Hohaia, W.; Yarrow, K.; Johnston, A.; Arnold, D. H.

10.1101/2020.02.19.951566 — neuroscience — Posted on 2020-02-20

1229 The impact of rare and common genetic variation in theInterleukin-1 pathway for human cytokine responses

van Deuren, R. C.; Arts, P.; Cavalli, G.; Jaeger, M.; Steehouwer, M.; van de Vorst, M.; Gilissen, C.; Joosten, L. A.; Dinarello, C. A.; Mhlanga, M. M.; Kumar, V.; Netea, M. G.; van de Veerdonk, F. L.; Hoischen, A.

10.1101/2020.02.14.949602 — systems biology — Posted on 2020-02-20

1230 Knowledge guided multi-level network inference

Ogris, C.; Hu, Y.; Arloth, J.; Mueller, N. S.

10.1101/2020.02.19.953679 — systems biology — Posted on 2020-02-20

1231 Building a robust chromatin immunoprecipitation (ChIP) method with substantially improved efficiency

Zhao, H.; Li, H.; Jia, Y.; Wen, X.; Guo, H.; Xu, H.; Wang, Y.

10.1101/2020.02.20.958330 — plant biology — Posted on 2020-02-20

1232 Physiological and cognitive consequences of a daily 26h photoperiod in a primate (M. murinus)

HOZER, C.; PIFFERI, F.

10.1101/2020.02.19.955674 — physiology — Posted on 2020-02-20

1233 The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies?

Tinning, H.; Taylor, A.; Wang, D.; Constantinides, B.; Sutton, R.; Oikonomou, G.; Velazquez, M. A.; Thompson, P.; Treumann, A.; O'Connell, M. J.; Forde, N.

10.1101/2020.02.19.953794 — physiology — Posted on 2020-02-20

1234 Evidence for immediate enhancement of medial-temporal lobe memory processing by network-targeted theta-burst stimulation during concurrent fMRI

Hermiller, M. S.; Chen, Y.; Parrish, T.; Voss, J. L.

10.1101/2020.02.19.956466 — neuroscience — Posted on 2020-02-20

1235 Molecular classification of the placebo effect in nausea

Meissner, K.; Lutter, D.; von Toerne, C.; Haile, A.; Woods, S. C.; Hoffmann, V.; Ohmayer, U.; Hauck, S. M.; Tschoep, M. H.

10.1101/2020.02.19.955740 — neuroscience — Posted on 2020-02-20

1236 Cooperation between CRISPR-Cas types enables adaptation in an RNA-targeting system

Hoikkala, V.; Ravantti, J. J.; Diez-Villasenor, C.; Tiirola, M.; Conrad, R.; McBride, M. J.; Sundberg, L.-R.

10.1101/2020.02.20.957498 — microbiology — Posted on 2020-02-20

1237 Does methylation of NFATC1 and C-FOS genes are associated with post-menopausal osteoporosis?

Kalkan, R.; Tosun, O.

10.1101/2020.02.19.955682 — genetics — Posted on 2020-02-20

1238 Ecological niche models as hypothesis generators of functional genetic differentiation and potential local adaptation in a Mediterranean alpine ecosystem

Morente-Lopez, J.; Kass, J. M.; Lara-Romero, C.; Serra-Diaz, J. M.; Soto-Correa, J. C.; Anderson, R. P.; Iriondo, J. M.

10.1101/2020.02.18.954867 — evolutionary biology — Posted on 2020-02-20

1239 Mutation bias interacts with composition bias to influence adaptive evolution

V. Cano, A.; Payne, J. L.

10.1101/2020.02.20.957217 — evolutionary biology — Posted on 2020-02-20

1240 The limits to parapatric speciation 3: Evolution of strong reproductive isolation in presence of gene flow despite limited ecological differentiation.

Blanckaert, A.; Bank, C.; Hermisson, J.

10.1101/2020.02.19.956292 — evolutionary biology — Posted on 2020-02-20

1241 GREM1 is epigenetically reprogrammed in muscle cells after exercise training and controls myogenesis and metabolism

Fabre, O.; Giordani, L.; Parisi, A.; Pattamaprapanont, P.; Ahwazi, D.; Brun, C. E.; Chakroun, I.; Taleb, A.; Blais, A.; Andersen, E.; Ingerslev, L. R.; Maire, P.; Rudnicki, M. A.; Laurens, C.; Citirikkaya, K.; Garde, C.; Lundell, L.; Desmukh, A. S.; Moro, C.; Bourlier, V.; Mounier, R.; Le Grand, F.; Barres, R.

10.1101/2020.02.20.956300 — cell biology — Posted on 2020-02-20

1242 Voting-based integration algorithm improves causal network learning from interventional and observational data: an application to cell signaling network inference

Sinha, M.; Tadepalli, P.; Ramsey, S. A.

10.1101/2020.02.18.955153 — bioinformatics — Posted on 2020-02-20

1243 Expression of a Barhl1a reporter in subsets of retinal ganglion cells and commissural neurons of the developing zebrafish brain

Albadri, S.; Armant, O.; Aljand-Geschwill, T.; Del Bene, F.; Carl, M.; Straehle, U.; Poggi, L.

10.1101/2020.02.20.957795 — developmental biology — Posted on 2020-02-20

1244 Tudor staphylococcal nuclease acts as a docking platform for stress granule components in Arabidopsis thaliana

Gutierrez-Beltran, E.; Elander, P. H.; Dalman, K.; Crespo, J. L.; Moschou, P. N.; Uversky, V. N.; Bozhkov, P. V.

10.1101/2020.02.20.955922 — plant biology — Posted on 2020-02-20

1245 High standing genetic variation in an invasive plant allows immediate evolutionary response to climate warming

Sun, Y.; Bossdorf, O.; Grados, R. D.; Liao, Z.; Mueller-Schaerer, H.

10.1101/2020.02.20.957209 — evolutionary biology — Posted on 2020-02-20

1246 Crystal structure of the 2019-nCoV spike receptor-binding domain bound with the ACE2 receptor

Lan, J.; Ge, J.; Yu, J.; Shan, S.; Zhou, H.; Fan, S.; Zhang, Q.; Shi, X.; Wang, Q.; Zhang, L.; Wang, X.

10.1101/2020.02.19.956235 — biophysics — Posted on 2020-02-20

1247 Structural basis for the recognition of the 2019-nCoV by human ACE2

Yan, R.; Zhang, Y.; Guo, Y.; Xia, L.; Zhou, Q.

10.1101/2020.02.19.956946 — biochemistry — Posted on 2020-02-20

1248 X-ray Structure of Main Protease of the Novel Coronavirus SARS-CoV-2 Enables Design of α-Ketoamide Inhibitors

Zhang, L.; Lin, D.; Sun, X.; Rox, K.; Hilgenfeld, R.

10.1101/2020.02.17.952879 — biochemistry — Posted on 2020-02-20

1249 Histo-molecular differentiation of renal cancer subtypes by imaging mass spectrometry and rapid proteome profiling

Möginger, U.; Marcussen, N.; Jensen, O. N.

10.1101/2020.02.19.956433 — biochemistry — Posted on 2020-02-20

1250 SARS-CoV-2 and SARS-CoV Spike-RBD Structure and Receptor Binding Comparison and Potential Implications on Neutralizing Antibody and Vaccine Development

Xie, L.; Sun, C.; Luo, C.; Zhang, Y.; Zhang, J.; Yang, J.; Chen, L.; Yang, J.; Li, J.

10.1101/2020.02.16.951723 — microbiology — Posted on 2020-02-20

1251 Septins disruption controls tumor growth and enhances efficacy of Herceptin

Singh, R. K.; Kim, K. K.; Khazan, N.; Rowswell_Turner, R. B.; Laggner, C.; Jones, A.; Srivastava, P.; Hovanesian, V.; Lamere, L.; Conley, T.; Pandita, R.; Baker, C.; Myers, J. R.; Prichett, E.; Awada, A.; Ruffolo, L.; Jackson, C.; Gerber, S.; Ashton, J.; Milano, M. T.; Linehan, D.; Moore, R.

10.1101/2020.02.19.954529 — cancer biology — Posted on 2020-02-20

1252 Interactive machine learning for fast and robust cell profiling

Laux, L.; Cutiongco, M. F.; Gadegaard, N.; Jensen, B. S.

10.1101/2020.02.20.956268 — bioinformatics — Posted on 2020-02-20

1253 Pangolin homology associated with 2019-nCoV

Zhang, Z.; Wu, Q.; Zhang, T.

10.1101/2020.02.19.950253 — pathology — Posted on 2020-02-20

1254 Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

Plante, J. A.; Plante, K.; Gralinski, L.; Beall, A.; Ferris, M. T.; Bottomly, D.; Green, R. R.; McWeeney, S.; Heise, M. T.; Baric, R. S.; Menachery, V. D.

10.1101/2020.02.19.957118 — microbiology — Posted on 2020-02-20

1255 Is FAM19A5 an adipokine? Peripheral FAM19A5 in wild-type, FAM19A5 knock-out, and LacZ knock-in mice.

Kwak, H.; Cho, E.-H.; Cho, E. B.; Lee, Y.-N.; Shahapal, A.; Yong, H. J.; Reyes-Alcaraz, A.; Jeong, Y.; Lee, Y.; Lee, M.; Ha, N.; Oh, S.; Lee, J. K.; Lee, W. S.; Kim, W.; Hwang, J.-I.; Seong, J. Y.

10.1101/2020.02.19.955351 — genetics — Posted on 2020-02-20

1256 Inferring directional relationships in microbial communities using signed Bayesian networks

Sazal, M. R.; Mathee, K.; Ruiz-Perez, D.; Cickovski, T.; Narasimhan, G.

10.1101/2020.02.18.955344 — bioinformatics — Posted on 2020-02-20

1257 Spatiotemporal identification of druggable binding sites using deep learning

Kozlovskii, I.; Popov, P.

10.1101/2020.02.20.952309 — bioinformatics — Posted on 2020-02-20

1258 Promoter keyholes enable specific and persistent multi-gene expression programs in primary T cells without genome modification

10.1101/2020.02.19.956730 — synthetic biology — Posted on 2020-02-20

1259 Long-Read cDNA Sequencing Enables a 'Gene-Like' Transcript Annotation of Arabidopsis Transposable Elements

Panda, K.; Slotkin, R. K.

10.1101/2020.02.20.956714 — plant biology — Posted on 2020-02-20

1260 The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer

Millar, R.; Kilbey, A.; Remak, S.-J.; Severson, T. M.; Dhayade, S.; Sandilands, E.; Foster, K.; Bryant, D. M.; Blyth, K.; Coffelt, S. B.

10.1101/2020.02.19.956508 — cancer biology — Posted on 2020-02-20

1261 Assessing relationships between chromatin interactions and regulatory genomic activities using the self-organizing map

Kunz, T.; Rieber, L.; Mahony, S.

10.1101/2020.02.20.951616 — bioinformatics — Posted on 2020-02-20

1262 Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase.

Chen, J. Z.; Fowler, D. M.; Tokuriki, N.

10.1101/2020.02.19.956706 — biochemistry — Posted on 2020-02-20

1263 BiteOscope: an open platform to study mosquito blood-feeding behavior

Hol, F. J.; Lambrechts, L.; Prakash, M.

10.1101/2020.02.19.955641 — animal behavior and cognition — Posted on 2020-02-20

1264 Phage composition of a fermented milk and colostrum product assessed by microbiome array; putative role of open reading frames in reference to cell signaling and neurological development

Pacini, S.; Ruggiero, M.

10.1101/714154 — microbiology — Posted on 2020-02-20

1265 Assessment of mitochondrial physiology of murine white adipose tissue by mechanical permeabilization and lipid depletion

Romeiro, N. C.; Ferreira, C. M.; Oliveira, M.

10.1101/2020.02.19.956870 — biochemistry — Posted on 2020-02-20

1266 Respiratory and gut microbiota in commercial turkey flocks with disparate weight gain trajectories display differential compositional dynamics

Taylor, K. J.; Ngunjiri, J. M.; Abundo, M.; Jang, H.; Elaish, M.; Ghorbani, A.; KC, M.; Weber, B.; Johnson, T. J.; Lee, C. W.

10.1101/2020.02.19.957092 — microbiology — Posted on 2020-02-20

1267 Swine Growth Promotion with Antibiotics or Alternatives Increases Antibiotic Resistance Gene Mobility Potential in the Fecal Microbiome

Muurinen, J.; Richert, J. A.; Wickware, C.; Richert, B. T.; Johnson, T. A.

10.1101/2020.02.19.957100 — microbiology — Posted on 2020-02-20

1268 Heimdallarchaeota harness light energy through photosynthesis

Liu, R.; Cai, R.; Zhang, J.; Sun, C.

10.1101/2020.02.20.957134 — microbiology — Posted on 2020-02-20

1269 CoolMPS™: Advanced massively parallel sequencing using antibodies specific to each natural nucleobase

Drmanac, S.; Callow, M.; Chen, L.; Zhou, P.; Eckhardt, L.; Xu, C.; Gong, M.; Gablenz, S.; Rajagopal, J.; Yang, Q.; Villarosa, C.; Au, A.; Davis, K.; Jorjorian, A.; Wang, J.; Chen, A.; Zhang, X.; Borcherding, A.; Wei, X.; Zhang, M.; Xie, Y.; Barua, N.; Shafto, J.; Dong, Y.; Zheng, Y.; Wang, L.; Zhai, L.; Li, J.; Liao, S.; Zhang, W.; Liu, J.; Jiang, H.; Wang, J.; Li, H.; Xu, X.; Drmanac, R.

10.1101/2020.02.19.953307 — genomics — Posted on 2020-02-20

1270 A method for predicting evolved fold switchers exclusively from their sequences

Kim, A. K.; Looger, L. L.; Porter, L.

10.1101/2020.02.19.956805 — bioinformatics — Posted on 2020-02-20

1271 Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein

Walls, A. C.; Park, Y.-J.; Tortorici, M. A.; Wall, A.; McGuire, A. T.; Veesler, D.

10.1101/2020.02.19.956581 — biochemistry — Posted on 2020-02-20

1272 Are pangolins the intermediate host of the 2019 novel coronavirus (2019-nCoV) ?

Liu, P.; Jiang, J.-Z.; Hua, Y.; Wang, X.; Hou, F.; Wan, X.-F.; Chen, J.; Zou, J.; Chen, J.

10.1101/2020.02.18.954628 — pathology — Posted on 2020-02-20

1273 Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins

Xiao, K.; Zhai, J.; Feng, Y.; Zhou, N.; Zhang, X.; Zou, J.-J.; Li, N.; Guo, Y.; Li, X.; Shen, X.; Zhang, Z.; Shu, F.; Huang, W.; Li, Y.; Zhang, Z.; Chen, R.-A.; Wu, Y.-J.; Peng, S.-M.; Huang, M.; Xie, W.-J.; Cai, Q.-H.; Hou, F.-H.; Liu, Y.; Chen, W.; Xiao, L.; Shen, Y.

10.1101/2020.02.17.951335 — microbiology — Posted on 2020-02-20

1274 Aberrant pathogenic GM-CSF+ T cells and inflammatory CD14+CD16+ monocytes in severe pulmonary syndrome patients of a new coronavirus

Zhou, Y.; Fu, B.; Zheng, X.; Wang, D.; Zhao, C.; Qi, Y.; Sun, R.; Tian, Z.; Xu, X.; Wei, H.

10.1101/2020.02.12.945576 — immunology — Posted on 2020-02-20

1275 Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions

Grifoni, A.; Sidney, J.; Zhang, Y.; Scheuermann, R. H.; Peters, B. H.; Sette, A.

10.1101/2020.02.12.946087 — immunology — Posted on 2020-02-20

1276 Multivariate Analyses of Codon Usage in 2019 Novel Coronavirus on the Genomic Landscape of Betacoronavirus

Gu, H.; Chu, D. K. W.; Peiris, J. S. M.; Poon, L. L. M.

10.1101/2020.02.15.950568 — evolutionary biology — Posted on 2020-02-20

1277 Metabolic Buffer Analysis Reveals the Simultaneous, Independent Control of ATP and Adenylate Energy Ratios

Hancock, E. J.; Krycer, J. R.; Ang, J.

10.1101/2020.02.19.957035 — systems biology — Posted on 2020-02-20

1278 C. elegans nuclear RNAi factor SET-32 deposits the transgenerational heritable histone modification, H3K23me3

Schwartz-Orbach, L.; Zhang, C.; Sidoli, S.; Amin, R.; Kaur, D.; Zhebrun, A.; Ni, J.; Gu, S. G.

10.1101/2020.02.19.956656 — molecular biology — Posted on 2020-02-20

1279 Urine as a high-quality source of host genomic DNA from wild populations

Ozga, A. T.; Webster, T. H.; Gilby, I. C.; Wilson, M. A.; Nockerts, R. S.; Wilson, M. L.; Pusey, A. E.; Li, Y.; Hahn, B. H.; Stone, A. C.

10.1101/2020.02.18.955377 — genomics — Posted on 2020-02-20

1280 Temporal and spatial dynamics in the apple flower microbiome in the presence of the phytopathogen Erwinia amylovora

Cui, Z.; Huntley, R. B.; Zeng, Q.; Steven, B.

10.1101/2020.02.19.956078 — microbiology — Posted on 2020-02-20

1281 Evidence of climate change impacts on the iconic Welwitschia mirabilis in the Namib Desert

Bombi, P.; Salvi, D.; Shuuya, T.; Vignoli, L.; Wassenaar, T.

10.1101/2020.02.19.955823 — ecology — Posted on 2020-02-20

1282 Long non-coding RNA LINC00152 plays an oncogenic role via targeting STAT3 and c-MYC signaling in esophageal adenocarcinoma

Zhao, H.; Xiao, M.; Zhao, H.; Wang, Z.; Nancarrow, D.; Chen, G.

10.1101/2020.02.19.956920 — cancer biology — Posted on 2020-02-20

1283 Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Bowden, A. R.; Morales Juarez, D. A.; Sczaniecka-Clift, M.; Agudo, M. M.; Lukashchuk, N.; Thomas, J. C.; Jackson, S.

10.1101/2020.02.20.957746 — genomics — Posted on 2020-02-20

1284 Cooption of polyalanine tract into a repressor domain in the mammalian transcription factor HoxA11

Lynch, V. J.; Wagner, G.

10.1101/2020.02.19.956243 — evolutionary biology — Posted on 2020-02-20

1285 Antifungal symbiotic peptide NCR044.1 exhibits unique structure and multi-faceted mechanisms of action that confer plant protection

Velivelli, S. L. S.; Czymmek, K. J.; Li, H.; Shaw, J. B.; Buchko, G. W.; Shah, D. M.

10.1101/2020.02.19.956318 — plant biology — Posted on 2020-02-20

1286 The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates

Riad, A.; Lengyel-Zhand, Z.; Zeng, C.; Weng, C.-C.; Lee, V. M.- Y.; Trojanowski, J. Q.; Mach, R. H.

10.1101/2020.02.19.956359 — neuroscience — Posted on 2020-02-20

1287 Chronic chemogenetic activation of forebrain excitatory neurons in postnatal life evokes long-lasting changes in mood-related behavior

Pati, S.; Saba, K.; Salvi, S. S.; Tiwari, P.; Chaudhari, P. R.; Verma, V.; Mukhopadhyay, S.; Kapri, D.; Suryavanshi, S.; Clement, J. P.; Patel, A. B.; Vaidya, V. A.

10.1101/2020.02.19.956060 — neuroscience — Posted on 2020-02-20

1288 Endonuclease activity of RecJ from extremely alkaliphilic Bacillus alcalophilus

Zheng, M.; Wang, W.; Ma, L.; Wang, L.; Qu, L.; Liu, X.; Liu, H.

10.1101/2020.02.19.956169 — microbiology — Posted on 2020-02-20

1289 Mutations in TAC1B: a novel genetic determinant of clinical fluconazole resistance in C. auris

Rybak, J. M.; Munoz, J. F.; Barker, K. S.; Parker, J.; Esquivel, B. D.; Berkow, E. L.; Lockhart, S. R.; Gade, L.; Palmer, G. E.; White, T. C.; Kelly, S. L.; Cuomo, C. A.; Rogers, P. D.

10.1101/2020.02.18.955534 — microbiology — Posted on 2020-02-20

1290 Redundant function of Ets1 and Ets2 in regulating M-phase progression in post-natal angiogenesis

Ghosh, S.; MarElia-Bennett, C. B.; Hildreth, B. E.; Lefler, J. E.; Sharma, S. M.; Ostrowski, M. C.

10.1101/2020.02.19.956417 — genomics — Posted on 2020-02-20

1291 Genetic architecture of oxidative stress tolerance in the fungal wheat pathogen Zymoseptoria tritici

Palma-Guerrero, J.; Zhong, Z.; McDonald, B. A.

10.1101/2020.02.20.957431 — genetics — Posted on 2020-02-20

1292 Sampling bias and model choice in continuous phylogeography: getting lost on a random walk

Kalkauskas, A.; Perron, U.; Sun, Y.; Goldman, N.; Baele, G.; Guindon, S.; De Maio, N.

10.1101/2020.02.18.954057 — evolutionary biology — Posted on 2020-02-20

1293 Revisiting the expression signature of pks15/1 unveils regulatory patterns controlling phenolphtiocerol and phenolglycolipid production in pathogenic mycobacteria

Ramos, B.; Gordon, S. V.; Cunha, M. V.

10.1101/2020.02.20.950329 — genomics — Posted on 2020-02-20

1294 Enhanced production of heterologous proteins by a synthetic microbial community: Conditions and trade-offs

Mauri, M.; Gouze, J.-L.; de Jong, H.; Cinquemani, E.

10.1101/2020.02.19.955815 — systems biology — Posted on 2020-02-20

1295 Molecular origins of transcriptional heterogeneity in diazotrophic K. oxytoca

Bashir, T.; Brackston, R. D.; Waite, C. J.; Kotta-Loizou, I.; Engl, C.; Buck, M.; Schumacher, J.

10.1101/2020.02.18.955476 — microbiology — Posted on 2020-02-20

1296 Portuguese wild grapevine genome re-sequencing (Vitis vinifera sylvestris)

Ramos, M. J. N.; Coito, J. L.; Silva, D. F.; Cunha, J.; Costa, M. M. R.; Amancio, S.; Rocheta, M.

10.1101/2020.02.19.955781 — plant biology — Posted on 2020-02-20

1297 Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

Martin, J. T.; Cottrell, C. T.; Antanasijevic, A.; Carnathan, D. G.; Cossette, B. J.; Enemuo, C. A.; Gebru, E. H.; Choe, Y.; Viviano, F.; Tokatlian, T.; Cirelli, K. M.; Ueda, G.; Copps, J.; Schiffner, T.; Menis, S.; Schief, W. R.; Crotty, S.; King, N. P.; Baker, D.; Silvestri, G.; Ward, A.; Irvine, D. J.

10.1101/2020.02.19.956482 — immunology — Posted on 2020-02-20

1298 Integrated analysis of the aging brain transcriptome and proteome in tauopathy

Mangleburg, C. G.; Wu, T.; Yalamanchili, H. K.; Guo, C.; Hsieh, Y.-C.; Duong, D. M.; Dammer, E. B.; De Jager, P. L.; Seyfried, N. T.; Liu, Z.; Shulman, J. M.

10.1101/2020.02.19.954578 — genomics — Posted on 2020-02-20

1299 Prevalence and global distribution of blaKPC-2 and blaNDM-1 genes in Klebsiella Pneumoniae

Xiufeng, Z.; Fangping, L.; Xiaohua, L.; Lisha, M.; Yixing, L.; Awan, F.; Weibiao, L.; Zhenling, Z.

10.1101/2020.02.18.955211 — bioinformatics — Posted on 2020-02-20

1300 μCB-seq: Microfluidic cell barcoding and sequencing for high-resolution imaging and sequencing of single cells

Chen, T. N.; Gupta, A. N.; Zalavadia, M. D.; Streets, A.

10.1101/2020.02.18.954974 — bioengineering — Posted on 2020-02-20

1301 Inositol synthesis gene is required for circadian rhythm of Drosophila melanogaster mating behavior.

Sakata, K.; Kawasaki, H.; Ishida, N.

10.1101/2020.02.19.955583 — animal behavior and cognition — Posted on 2020-02-20

1302 Cold priming memory reduces plant pathogen susceptibility based on a functional plastid peroxidase system

Griebel, T.; Ebert, A.; Nguyen, H. H.; Baier, M.

10.1101/2020.02.19.956540 — plant biology — Posted on 2020-02-20

1303 CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration

Zhou, C.; Hu, X.; Tang, C.; Liu, W.; Wang, S.; Zhou, Y.; Zhao, Q.; Bo, Q.; Shi, L.; Sun, X.; Zhou, H.; Yang, H.

10.1101/2020.02.18.955286 — genetics — Posted on 2020-02-20

1304 Museum phylogenomics of extinct Oryctes beetles from the Mascarene Islands

Latorre, S. M.; Herrmann, M.; Paulsen, M. J.; Rödelsperger, C.; Dreau, A.; Röseler, W.; Sommer, R. J.; Burbano, H. A.

10.1101/2020.02.19.954339 — evolutionary biology — Posted on 2020-02-20

1305 High-throughput laboratory evolution and evolutionary constraints in Escherichia coli

Maeda, T.; Iwasawa, J.; Kotani, H.; Sakata, N.; Kawada, M.; Horinouchi, T.; Sakai, A.; Tanabe, K.; Furusawa, C.

10.1101/2020.02.19.956177 — evolutionary biology — Posted on 2020-02-20

1306 Kaposi's sarcoma-associated herpesvirus fine-tunes the temporal expression of late genes by manipulating a host RNA quality control pathway

Ruiz, J. C.; Devlin, A. M.; Kim, J.; Conrad, N. K.

10.1101/2020.02.18.955526 — microbiology — Posted on 2020-02-20

1307 Multi-omic surveillance of Escherichia coli and Klebsiella spp. in hospital sink drains and patients

10.1101/2020.02.19.952366 — microbiology — Posted on 2020-02-20

1308 Photon-directed Multiplexed Enzymatic DNA Synthesis for Molecular Digital Data Storage

Lee, H.; Wiegand, D. J.; Griswold, K.; Punthambaker, S.; Chun, H.; Kohman, R. E.; Church, G. M.

10.1101/2020.02.19.956888 — synthetic biology — Posted on 2020-02-20

1309 Survey of Australian STEMM Early Career Researchers: job insecurity and questionable research practices are major structural concerns

Christian, K.; Johnstone, C.; Larkins, J.-a.; Wright, W.; Doran, M. R.

10.1101/2020.02.19.955328 — scientific communication and education — Posted on 2020-02-20

1310 Social isolation modulates appetite and defensive behavior via a common oxytocinergic circuit in larval zebrafish

Wee, C. L.; Song, E. Y.; Nikitchenko, M.; Wong, S.; Engert, F.; Kunes, S.

10.1101/2020.02.19.956854 — neuroscience — Posted on 2020-02-20

1311 Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endodermal gene regulatory network

Mukherjee, S.; Chaturvedi, P.; Rankin, S. A.; Fish, M. B.; Wizla, M.; Paraiso, K. D.; MacDonald, M.; Chen, X.; Weirauch, M. T.; Blitz, I. L.; Cho, K. W. Y.; Zorn, A.

10.1101/2020.02.19.956565 — developmental biology — Posted on 2020-02-20

1312 A quantitative principle to understand 3D cellular connectivity in epithelial tubes

Gomez-Galvez, P.; Vicente-Munuera, P.; Anbari, S.; Tagua, A.; Gordillo, C.; Palacios, A. M.; Velasco, A.; Capitan-Agudo, C.; Grima, C.; Annese, V.; Robles, R.; Marquez, A.; Buceta, J.; Escudero, L. M.

10.1101/2020.02.19.955567 — developmental biology — Posted on 2020-02-20

1313 Humanisation of the zebrafish C5a receptor confers targeting by human-specific staphylococcal virulence factors.

Buchan, K. D.; van Gent, M.; Prajsnar, T. K.; Ogryzko, N. V.; de Jong, N.; Kolata, J.; Foster, S. J.; van Strijp, J. A.; Renshaw, S. A.

10.1101/2020.02.18.955021 — immunology — Posted on 2020-02-20

1314 Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner

Bayik, D.; Zhou, Y.; Park, C.; Hong, C.; Vail, D.; Silver, D. J.; Lauko, A. J.; Roversi, G. A.; Watson, D. C.; Lo, A.; Alban, T. J.; McGraw, M.; Sorensen, M. D.; Grabowski, M. M.; Otvos, B.; Vogelbaum, M. A.; Horbinski, C. M.; Kristensen, B. W.; Khalil, A. M.; Hwang, T. H.; Ahluwalia, M. S.; Cheng, F.; Lathia, J.

10.1101/2020.02.19.954552 — immunology — Posted on 2020-02-20

1315 A novel drug-combination screen in zebrafish identifies epigenetic small molecule candidates for Duchenne muscular dystrophy

Farr, G. H.; Morris, M.; Gomez, A.; Pham, T.; Parker, E. U.; Kilroy, E.; Said, S.; Henry, C.; Maves, L.

10.1101/2020.02.19.956532 — pharmacology and toxicology — Posted on 2020-02-20

1316 Synaptic and supra-synaptic organisation of the dopaminergic projection to the striatum.

Pfeffer, M. E.; Pronot, M.; Angelo, M. F.; Walle, R.; Cordelieres, F. P.; Levet, F.; Claverol, S.; Lacome, S.; Petrel, M.; Martin, C.; Pitard, V.; Desmedt-Peyrusse, V.; Biederer, T.; Trifilieff, P.; Herzog, E.

10.1101/2020.02.18.952978 — neuroscience — Posted on 2020-02-20

1317 Immunological role of primary cilia of dendritic cells in human skin disease

Toriyama, M.; Rizaldy, D.; Nakamura, M.; Fujita, F.; Okada, F.; Morita, A.; Ishii, K. J.

10.1101/2020.02.04.933333 — cell biology — Posted on 2020-02-20

1318 Temporal dynamics of GABA and Glx in the visual cortex

Rideaux, R.

10.1101/2020.01.15.907659 — neuroscience — Posted on 2020-02-20

1319 Voltage-gated ion channels mediate the electrotaxis of glioblastoma cells in a hybrid PMMA/PDMS microdevice

Tsai, H.-F.; IJspeert, C.; Shen, A. Q.

10.1101/2020.02.14.948638 — cell biology — Posted on 2020-02-20

1320 Quantitative and molecular differences distinguish adult human medullary and extramedullary haematopoietic stem and progenitor cell landscapes

Mende, N.; Bastos, H.; Santoro, A.; Sham, K.; Mahbubani, K. T.; Curd, A.; Takizawa, H.; Wilson, N. K.; Gottgens, B.; Saeb-Parsy, K.; Laurenti, E.

10.1101/2020.01.26.919753 — cell biology — Posted on 2020-02-20

1321 Mitochondrial fission, integrity and clearance require separable functions of Vps13D inDrosophila neurons

Insolera, R.; Lorincz, P.; Wishnie, A. J.; Juhasz, G.; Collins, C. A.

10.1101/2020.01.21.914523 — cell biology — Posted on 2020-02-20

1322 A multi-layered systems approach for renal cell carcinoma

Cooley, L.; Rudewicz, J.; Souleyreau, W.; Clarke, K.; Falciani, F.; Dufies, M.; Verbeke, S.; Emanuelli, A.; Benzekry, S.; Taing, C.; Ribot, E. J.; Miraux, S.; Lambrechts, D.; Modave, E.; Pineau, R.; Derieppe, M.-A.; Ambrosetti, D.; Bernhard, J.-C.; Ravaud, A.; Negrier, S.; Ferrero, J.-M.; Pages, G.; Nikolski, M.; Bikfalvi, A.

10.1101/2020.01.13.904235 — cancer biology — Posted on 2020-02-20

1323 APA-Scan: Detection and Visualization of 3'-UTR APA with RNA-seq and 3'-end-seq Data

Fahmi, N. A.; Chang, J.-W.; Nassereddeen, H.; Ahmed, K. T.; Fan, D.; Yong, J.; Zhang, W.

10.1101/2020.02.16.951657 — bioinformatics — Posted on 2020-02-20

1324 Model Reduction Tools For Phenomenological Modeling of Input-Controlled Biological Circuits

Pandey, A.; Murray, R. M.

10.1101/2020.02.15.950840 — synthetic biology — Posted on 2020-02-20

1325 Disadvantages of writing, reading, publishing and presenting scientific papers caused by the dominance of the English language in science: The case of Colombian Ph.D. in biological sciences

Ramirez-Castaneda, V.

10.1101/2020.02.15.949982 — scientific communication and education — Posted on 2020-02-20

1326 Rethinking success, integrity, and culture in research (Part 2) -- A multi-actor qualitative study on problems of science

Aubert Bonn, N.; Pinxten, W.

10.1101/2020.02.12.945899 — scientific communication and education — Posted on 2020-02-20

1327 AtCIPK16 Mediates Salt Stress Potentially Through Phytohormones and Transcription Factors

Amarasinghe, S. L.; Huang, W.; Watson-Haigh, N. S.; Gilliham, M.; Roy, S. J.; Baumann, U.

10.1101/2020.02.17.953216 — plant biology — Posted on 2020-02-20

1328 Reliable Readout of Mixture Components from Small Populations of Anterior Piriform Cortical Neurons

Penker, S.; Licht, T.; Hofer, K. T.; Rokni, D.

10.1101/2019.12.26.888693 — neuroscience — Posted on 2020-02-20

1329 Visual feature tuning of superior colliculus neural reafferent responses after fixational microsaccades

Khademi, F.; Chen, C.-Y.; Hafed, Z. M.

10.1101/2019.12.24.888149 — neuroscience — Posted on 2020-02-20

1330 Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following demyelination

Saraswat, D.; Polanco, J. J.; Shayya, H. J.; Tripathi, A.; Welliver, R.; Pol, S. U.; Broome, J. E.; O'Bara, M. A.; van Kuppervelt, T. H.; Phillips, J. J.; Dutta, R.; Sim, F. J.

10.1101/2020.01.21.906073 — neuroscience — Posted on 2020-02-20

1331 O-GlcNAcylation and oxidation contribute to atrial fibrillation in diabetes by activating CaMKII

Mesubi, O. O.; Rokita, A. G.; Abrol, N.; Wu, Y.; Chen, B.; Wang, Q.; Granger, J. M.; Luczak, E. D.; Banerjee, P. S.; Maier, L. S.; Wehrens, X. H.; Pomerantz, J. L.; Song, L.-S.; Ahima, R. S.; Zachara, N. E.; Hart, G. W.; Anderson, M. E.

10.1101/2020.02.18.954909 — molecular biology — Posted on 2020-02-20

1332 ParB spreading on DNA requires cytidine triphosphate in vitro

Jalal, A. S. B.; Tran, N. T.; Le, T. B. K.

10.1101/2019.12.11.865972 — microbiology — Posted on 2020-02-20

1333 Differential gene expression in Drosophila melanogaster and D. nigrosparsa infected with the same Wolbachia strain

Detcharoen, M.; Schilling, M. P.; Arthofer, W.; Schlick-Steiner, B. C.; Steiner, F. M.

10.1101/2020.02.19.941534 — microbiology — Posted on 2020-02-20

1334 ErrorX: automated error correction for immune repertoire sequencing datasets

Sevy, A. M.

10.1101/2020.02.17.952408 — immunology — Posted on 2020-02-20

1335 Massively Parallel Analysis of Human 3' UTRs Reveals that AU-Rich Element Length and Registration Predict mRNA Destabilization

Siegel, D. A.; Le Tonqueze, O.; Biton, A.; Zaitlen, N.; Erle, D. J.

10.1101/2020.02.12.945063 — genomics — Posted on 2020-02-20

1336 Rewinding the molecular clock in the genus Carabus (Coleoptera: Carabidae): Revisiting Andujar et al. in light of new fossil evidence and the Gondwana split

Opgenoorth, L.; Hofmann, S.; Schmidt, J.

10.1101/2020.02.19.912543 — evolutionary biology — Posted on 2020-02-20

1337 AS-Quant: Detection and Visualization of Alternative Splicing Events with RNA-seq Data

Fahmi, N. A.; Yeh, H.-S.; Chang, J.-W.; Nassereddeen, H.; Fan, D.; Yong, J.; Zhang, W.

10.1101/2020.02.15.950287 — bioinformatics — Posted on 2020-02-20

1338 Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge

Sieberts, S. K.; Schaff, J.; Duda, M.; Pataki, B. A.; Sun, M.; Snyder, P.; Daneault, J.-F.; Parisi, F.; Costante, G.; Rubin, U.; Banda, P.; Chae, Y.; Neto, E. C.; Dorsey, R.; Aydın, Z.; Chen, A.; Elo, L. L.; Espino, C.; Glaab, E.; Goan, E.; Golabchi, F. N.; Görmez, Y.; Jaakkola, M. K.; Jonnagaddala, J.; KLEn, R.; Li, D.; McDaniel, C.; Perrin, D.; Rad, N. M.; Rainaldi, E.; Sapienza, S.; Schwab, P.; Shokhirev, N.; Venäläinen, M. S.; Vergara-Diaz, G.; Zhang, Y.; Parkinson's Disease Digital Biomarker Challenge Consortium, ; Wang, Y.; Guan, Y.; Brunner, D.; Bonato, P.; Mangravite, L. M.; Omberg

10.1101/2020.01.13.904722 — bioengineering — Posted on 2020-02-20

1339 Open microfluidic coculture reveals paracrine signaling from human kidney epithelial cells promotes kidney specificity of endothelial cells

Zhang, T.; Lih, D.; Nagao, R.; Xue, J.; Berthier, E.; Himmelfarb, J.; Zheng, Y.; Theberge, A. B.

10.1101/2020.02.14.949776 — bioengineering — Posted on 2020-02-20

1340 Love at first flight: Wing interference patterns are species-specific and sexually dimorphic in blowflies (Diptera: Calliphoridae)

Butterworth, N. J.; White, T. E.; Byrne, P. G.; Wallman, J. F.

10.1101/2020.02.18.948646 — evolutionary biology — Posted on 2020-02-20

1341 The genomic landscape of divergence across the speciation continuum in island-colonising silvereyes (Zosterops lateralis)

Sendell-Price, A. T.; Ruegg, K. C.; Anderson, E. C.; Quilodran, C. S.; Van Doren, B. M.; Underwood, V. L.; Coulson, T.; Clegg, S. M.

10.1101/2020.02.18.953893 — evolutionary biology — Posted on 2020-02-20

1342 How young is your Muscle? A Machine Learningframework for motor functional assessment with ageingby NMF based analysis of HD-sEMG signal.

BANERJEE, S.

10.1101/2020.02.12.946343 — bioengineering — Posted on 2020-02-20

1343 Elucidating the molecular interactions between uremic toxins and the Sudlow II binding site of human serum albumin

Smith, J.; Pfaendtner, J.

10.1101/2020.02.19.940171 — biochemistry — Posted on 2020-02-20

1344 Units of motor production: Bengalese finches interrupt song within syllables

Riedner, D.; Adam, I.

10.1101/2020.02.19.956698 — animal behavior and cognition — Posted on 2020-02-20

1345 Opportunities for prioritizing and expanding conservation enterprise in India using carnivores as flagships

Srivathsa, A.; Majgaonkar, I.; Sharma, S.; Punjabi, G. A.; Singh, P.; Chawla, M. M.; Banerjee, A.

10.1101/2020.01.03.894311 — ecology — Posted on 2020-02-20

1346 Hypercluster: a flexible tool for parallelized unsupervised clustering optimization

Blumenberg, L. M.; Ruggles, K. V.

10.1101/2020.01.13.905323 — bioinformatics — Posted on 2020-02-20

1347 PAM recognition by miniature CRISPR nucleases triggersprogrammable double-stranded DNA target cleavage

Karvelis, T.; Bigelyte, G.; Young, J. K.; Hou, Z.; Zedaveinyte, R.; Budre, K.; Paulraj, S.; Djukanovic, V.; Gasior, S.; Silanskas, A.; Venclovas, C.; Siksnys, V.

10.1101/654897 — biochemistry — Posted on 2020-02-20

1348 Auditory attention alterations in migraine: a behavioral and MEG/EEG study

Masson, R.; Leveque, Y.; Demarquay, G.; ElShafei, H. A.; Fornoni, L.; Lecaignard, F.; Morlet, D.; Bidet-Caulet, A.; Caclin, A.

10.1101/661413 — neuroscience — Posted on 2020-02-20

1349 Unexpected variability of allelic imbalance estimates from RNA sequencing

Mendelevich, A.; Vinogradova, S.; Gupta, S.; Mironov, A. A.; Sunyaev, S.; Gimelbrant, A. A.

10.1101/2020.02.18.948323 — bioinformatics — Posted on 2020-02-20

1350 Perturbing proteomes at single residue resolution using base editing

Despres, P. C.; Dube, A. K.; Seki, M.; Yachie, N.; Landry, C. R.

10.1101/677203 — synthetic biology — Posted on 2020-02-20

1351 Analysis of MRC-supported early career researcher success in obtaining follow-on research funding

Viney, I. S.; Dolby, K.; Samarisinghe, B.

10.1101/2020.02.19.949263 — scientific communication and education — Posted on 2020-02-20

1352 Magnetic Resonance Spectroscopy as a Non-invasive Method to Quantify Muscle Carnosine in Humans: a Comprehensive Validity Assessment

Silva, V. d. E.; Painelli, V. d. S.; Shinjo, S. K.; Ribeiro Pereira, W.; Cilli, E. M.; Sale, C.; Gualano, B.; Otaduy, M. C.; Artioli, G. G.

10.1101/568923 — physiology — Posted on 2020-02-20

1353 Distinct neural variables underlie subjective reports of attention

Whitmarsh, S.; Gitton, C.; Jousmäki, V.; Sackur, J.; Tallon-Baudry, C.

10.1101/2020.01.23.916841 — neuroscience — Posted on 2020-02-20

1354 Presynaptic inhibition of cutaneous afferents prevents self-generated itch

Escalante, A.; Klein, R.

10.1101/806976 — neuroscience — Posted on 2020-02-20

1355 Chronic stress exacerbates acute stress-induced neuronal activation in the anterior cingulate cortex and ventral hippocampus that correlates with behavioral deficits in mice

Fee, C.; Prevot, T. D.; Misquitta, K.; Banasr, M.; Sibille, E.

10.1101/2020.02.19.956672 — neuroscience — Posted on 2020-02-20

1356 EEG-based detection of the attended speaker and the locus of auditory attention with convolutional neural networks

Deckers, L.; Das, N.; Hossein Ansari, A.; Bertrand, A.; Francart, T.

10.1101/475673 — neuroscience — Posted on 2020-02-20

1357 Divergent effects of Western and Mediterranean diets on behavior and monocyte polarization

Johnson, C. S. C.; Shively, C. A.; Michalson, K. T.; Lea, A. J.; DeBo, R. J.; Howard, T. D.; Hawkins, G. A.; Appt, S. E.; Liu, Y.; McCall, C. E.; Herrington, D.; Register, T. C.; Snyder-Mackler, N.

10.1101/2020.01.27.917567 — genomics — Posted on 2020-02-20

1358 Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

Chundru, V. K.; Marioni, R. E.; Prendergast, J. G. D.; Lin, T.; Beveridge, A. J.; Martin, N. G.; Montgomery, G. W.; Hume, D. A.; Deary, I. J.; Visscher, P. M.; Wray, N. R.; McRae, A. F.

10.1101/2020.02.19.950659 — genetics — Posted on 2020-02-20

1359 Promoter CpG density is predictive of downstream gene loss-of-function intolerance

Boukas, L.; Bjornsson, H. T.; Hansen, K. D.

10.1101/2020.02.15.936351 — genetics — Posted on 2020-02-20

1360 Fly wing evolution explained by a neutral model with mutational pleiotropy

Jiang, D.; Zhang, J. G.

10.1101/2020.02.18.878595 — evolutionary biology — Posted on 2020-02-20

1361 Incorporating trait-based mechanisms, alternative interaction modes and forbidden links increases the minimum trait dimensionality of ecological networks

Kiziridis, D. A.; Boddy, L.; Eastwood, D. C.; Yuan, C.; Fowler, M. S.

10.1101/192260 — ecology — Posted on 2020-02-20

1362 Ecology of domestic dogs Canis familiaris as an emerging reservoir of Guinea worm Dracunculus medinensis infection

McDonald, R. A.; Wilson-Aggarwal, J. K.; Swan, G. J. F.; Goodwin, C. E. D.; Moundai, T.; Sankara, D.; Biswas, G.; Zingeser, J. A.

10.1101/2020.02.19.939827 — ecology — Posted on 2020-02-20

1363 Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation.

da Silva Rosa, S. C.; Martens, M. D.; Field, J. T.; Nguyen, L.; Kereliuk, S.; Hai, Y.; Chapman, D.; Diehl-Jones, W.; Aliani, M.; West, A. R.; Thliveris, J.; Ghavami, S.; Rampitsch, C.; Dolinsky, V. W.; Gordon, J.

10.1101/825828 — cell biology — Posted on 2020-02-20

1364 Automated Workflow For Peptide-level Quantitation From DIA/ SWATH-MS Data

Gupta, S.; Rost, H.

10.1101/2020.01.21.914788 — bioinformatics — Posted on 2020-02-20

1365 Development of a knowledge translation platform for ataxia: Impact on readers and volunteer contributors

Suart, C. E.; Graham, K.; Nowlan Suart, T. M.; Truant, R.

10.1101/2020.02.19.947853 — scientific communication and education — Posted on 2020-02-20

1366 Harmonization of diffusion MRI datasets with adaptive dictionary learning

St-Jean, S.; Viergever, M. A.; Leemans, A.

10.1101/824706 — neuroscience — Posted on 2020-02-19

1367 A brain network supporting social influences in human decision-making

Zhang, L.; Glascher, J. P.

10.1101/551614 — neuroscience — Posted on 2020-02-20

1368 Genotype Concordance and Polygenic Risk Score Estimation across Consumer Genetic Testing Data

Batra, P.; Huang, K.-l.

10.1101/795666 — genetics — Posted on 2020-02-19

1369 Hydrodynamic model of directional ciliary-beat organization in human airways

Gsell, S.; Loiseau, E.; D'Ortona, U.; Viallat, A.; Favier, J.

10.1101/2020.01.06.896001 — biophysics — Posted on 2020-02-19

1370 Hierarchical Markov Random Field model captures spatial dependency in gene expression, demonstrating regulation via the 3D genome

Zhou, N.; Friedberg, I.; Kaiser, M. S.

10.1101/2019.12.16.878371 — bioinformatics — Posted on 2020-02-19

1371 Deciphering gene regulation from gene expression dynamics using deep neural network

Shen, J.; Petkova, M. D.; Tu, Y.; Liu, F.; Tang, C.

10.1101/374439 — systems biology — Posted on 2020-02-19

1372 Bidirectional crosstalk between HIF and Glucocorticoid signalling in zebrafish larvae

Marchi, D.; Santhakumar, K.; Markham, E.; Li, N.; Storbeck, K.-H.; Krone, N.; Cunliffe, V. T.; van Eeden, F. J. M.

10.1101/748566 — physiology — Posted on 2020-02-19

1373 A Spiking Neuron and Population Model based on the Growth Transform Dynamical System

Gangopadhyay, A.; Mehta, D.; Chakrabartty, S.

10.1101/523944 — neuroscience — Posted on 2020-02-19

1374 Gene regulatory architectures dissect the evolutionary dynamics of regulatory elements in humans and non-human primates

Garcia-Perez, R.; Esteller-Cucala, P.; Mas, G.; Lobon, I.; Di Carlo, V.; Kuhlwilm, M.; Riera, M.; Navarro, A.; Blancher, A.; Di Croce, L.; Gomez-Skarmeta, J. L.; Juan, D.; Marques-Bonet, T.

10.1101/2019.12.18.872531 — evolutionary biology — Posted on 2020-02-19

1375 Identifying the fitness consequences of sex in complex natural environments

Rushworth, C.; Brandvain, Y. J.; Mitchell-Olds, T.

10.1101/719252 — ecology — Posted on 2020-02-19

1376 Replicate Engineered Virtual Patient Populations as Surrogates for Real Patient-Level Data

Alenghat, F. J.

10.1101/308403 — bioinformatics — Posted on 2020-02-19

1377 Quantifying dynamic protein acetylation using quantitative stoichiometry

Baeza, J.; Lawton, A. J.; Fan, J.; Smallegan, M. J.; Leinert, I.; Gandhi, T.; Bernhardt, O. M.; Reiter, L.; Denu, J. M.

10.1101/472530 — biochemistry — Posted on 2020-02-19

1378 The effect of stimulus choice on an EEG-based objective measure of speech intelligibility

Verschueren, E.; Vanthornhout, J.; Francart, T.

10.1101/421727 — neuroscience — Posted on 2020-02-19

1379 Effects of carbon-based additive and ventilation rate on nitrogen loss and microbial community during chicken manure composting

Chang, R.; Li, Y.; Chen, Q.; Gong, X.; Qi, Z.

10.1101/2020.02.19.956029 — bioengineering — Posted on 2020-02-19

1380 Impacts of climate change on agro-climatic suitability of major food crops and crop diversification potential in Ghana

Chemura, A.; Schauberger, B.; Gornott, C.

10.1101/2020.02.19.956011 — ecology — Posted on 2020-02-19

1381 The brain of Cataglyphis ants: neuronal organization and visual projections

Habenstein, J.; Amini, E.; Gruebel, K.; el Jundi, B.; Roessler, W.

10.1101/2020.02.19.954461 — neuroscience — Posted on 2020-02-19

1382 Differential Host Gene Signatures in Response to Mycobacterium tuberculosis Infection

Tazi, L.; Wang, P.; Fornage, M.

10.1101/2020.02.19.955203 — microbiology — Posted on 2020-02-19

1383 Analysis of structure of the population, kinship coeffcients and inbreeding trend depending on sex, type of breeding of Tatra Shepherd dogs

Niedziołka, R.; Sweklej, E.; Horoszewicz, E.

10.1101/2020.02.19.956045 — genetics — Posted on 2020-02-19

1384 Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6

Garcia-Doval, C.; Schwede, F.; Berk, C.; Rostol, J. T.; Niewoehner, O.; Tejero, O.; Hall, J.; Marraffini, L. A.; Jinek, M.

10.1101/2020.02.19.952960 — biochemistry — Posted on 2020-02-19

1385 NFκB dynamics determine stimulus-responsive epigenomic reprogramming in macrophages

Cheng, Q. J.; Ohta, S.; Sheu, K. M.; Spreafico, R.; Adelaja, A.; Taylor, B.; Hoffmann, A.

10.1101/2020.02.18.954602 — molecular biology — Posted on 2020-02-19

1386 Fe(III) heme sets an activation threshold for processing distinct groups of pri-miRNAs in mammalian cells

Weitz, S. H.; Quick-Cleveland, J.; Jacob, J. P.; Barr, I.; Senturia, R.; Koyano, K.; Xiao, X.; Weiss, S.; Guo, F.

10.1101/2020.02.18.955294 — molecular biology — Posted on 2020-02-19

1387 μ-Lat: A High-Throughput Humanized Mouse Model for Preclinical Evaluation of Human Immunodeficiency Virus Eradication Strategies

Sperber, H. S.; Togarrati, P. P.; Raymond, K. A.; Bouzidi, M. S.; Gilfanova, R.; Gutierrez, A. G.; Muench, M. O.; Pillai, S. K.

10.1101/2020.02.18.955492 — microbiology — Posted on 2020-02-19

1388 The transcriptional landscape of Venezuelan equine encephalitis virus infection

Yao, Z.; Zanini, F.; Kumar, S.; Panpradist, N.; Muniz, A.; Quake, S. R.; Einav, S.

10.1101/2020.02.18.955393 — microbiology — Posted on 2020-02-19

1389 Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver

Huang, P.; He, B.; Peng, W.; Huang, J.; Zhang, H.; Zhou, Y.; Yang, X.; Liu, J.; Li, Z.; Xu, C.; Xue, M.; Yang, H.

10.1101/2020.02.17.945014 — genomics — Posted on 2020-02-19

1390 Dynamic expressions of confidence within an evidence accumulation framework

Desender, K.; Donner, T. H.; Verguts, T.

10.1101/2020.02.18.953778 — neuroscience — Posted on 2020-02-19

1391 Dynamical persistence in resource-consumer models

Dalmedigos, I.; Bunin, G.

10.1101/2020.02.18.954008 — ecology — Posted on 2020-02-19

1392 TERT-mediated induction of MIR500A contributes to tumor invasiveness by targeting Hedgehog pathway

Bernabe-Garcia, M.; Martinez-Balsalobre, E.; Garcia-Moreno, D.; Garcia-Castillo, J.; Revilla-Nuin, B.; Blanco-Alcaina, E.; Mulero, V.; Alcaraz-Perez, F.; Cayuela, M. L.

10.1101/2020.02.18.954370 — cancer biology — Posted on 2020-02-19

1393 COMPOSITUM 1 (COM1) contributes to the architectural simplification of barley inflorescence via cell wall-mediated and meristem identity signals

Poursarebani, N.; Trautewig, C.; Melzer, M.; Nussbaumer, T.; Lundqvist, U.; Rutten, T.; Schmutzer, T.; Brandt, R.; Himmelbach, A.; Altschmied, L.; Koppolu, R.; Youssef, H. M.; Stein, N.; Xin, Z.; Schnurbusch, T.

10.1101/2020.02.18.952705 — plant biology — Posted on 2020-02-19

1394 Bile Acid pool composition and Gallbladder function are controlled by TGR5 to protect the liver against Bile Acid overload

BIDAULT-JOURDAINNE, V.; MERLEN, G.; GLENISSON, M.; DOIGNON, I.; GARCIN, I.; PEAN, N.; BOISGARD, R.; URSIC-BEDOYA, J.; SERINO, M.; ULLMER, C.; HUMBERT, L.; ABDELRAFEE, A.; VIBERT, E.; DUCLOS-VALLEE, J.-C.; RAINTEAU, D.; TORDJMANN, T.

10.1101/2020.02.18.954255 — physiology — Posted on 2020-02-19

1395 Dynamic contrast enhanced MRI with clinical hepatospecific MRI contrast agents in pigs: initial experience

Hix, J. M. L.; Mallett, C. L.; Latourette, M.; Munoz, K. A.; Shapiro, E. M.

10.1101/2020.02.18.946541 — physiology — Posted on 2020-02-19

1396 Src family kinases maintain latent sensitization, a model of inflammatory and neuropathic pain

Chen, W.; Marvizon, J. C. G.

10.1101/2020.02.18.954859 — neuroscience — Posted on 2020-02-19

1397 Modality-specific dysfunctional neural processing of social and non-social information in schizophrenia

He, Y.; Steines, M.; Sammer, G.; Nagels, A.; Kircher, T.; Straube, B.

10.1101/2020.02.18.953927 — neuroscience — Posted on 2020-02-19

1398 CRISPR-based Live Imaging of Epigenetic Modification-Mediated Genome Reorganization

Feng, Y.; Wang, Y.; Yang, C.; Naseri, A.; Pederson, T.; Zheng, J.; Xiao, X.; Zhang, S.; Xie, W.; Ma, H.

10.1101/2020.02.18.954610 — molecular biology — Posted on 2020-02-19

1399 Comparative Genome Analysis of Scutellaria baicalensis and Scutellaria barbata Reveals the Evolution of Active Flavonoid Biosynthesis

Xu, Z.; Gao, R.; Pu, X.; Xu, R.; Wang, J.; Zheng, S.; Zeng, Y.; Chen, J.; Song, J.

10.1101/2020.02.18.954164 — genomics — Posted on 2020-02-19

1400 Single-cell chromatin profiling reveals demethylation-dependent metabolic vulnerabilities of breast cancer epigenome

Kusi, M.; Zand, M.; Lin, C.-L.; Wang, C.-M.; Lucio, N. D.; Kirma, N. B.; Ruan, J.; Huang, T. H.- M.; Mitsuya, K.

10.1101/2020.02.18.954495 — cancer biology — Posted on 2020-02-19

1401 Constitutive activation of leucine-rich repeat receptor kinase signaling pathways by BAK1-interacting receptor-like kinase 3 chimera

Hohmann, U.; Ramakrishna, P.; Wang, K.; Lorenzo-Orts, L.; Nicolet, J.; Henschen, A.; Barberon, M.; Bayer, M.; Hothorn, M.

10.1101/2020.02.18.954479 — plant biology — Posted on 2020-02-19

1402 The genomic landscape of divergence across the speciation continuum in island-colonising silvereyes (Zosterops lateralis)

Sendell-Price, A. T.; Ruegg, K. C.; Anderson, E. C.; Quilodraan, C. S.; Van Doren, B. M.; Underwood, V. L.; Coulson, T.; Clegg, S. M.

10.1101/2020.02.18.953893 — evolutionary biology — Posted on 2020-02-19

1403 Vitamin D receptor protects against dysbiosis and tumorigenesis via the JAK/STAT pathway in intestine

Zhang, Y.-g.; Lu, R.; Wu, S.; Chatterjee, I.; Zhou, D.; Xia, Y.; Sun, J.

10.1101/2020.02.18.946335 — cancer biology — Posted on 2020-02-19

1404 Allosteric regulation of Thioesterase Superfamily Member 1 by free fatty acids and lysophosphatidylcholine

Tillman, M. C.; Imai, N.; Li, Y.; Khadka, M.; Okafor, C. D.; Juneja, P.; Adhiyaman, A.; Hagen, S. J.; Cohen, D. E.; Ortlund, E. A.

10.1101/2020.02.18.954917 — biochemistry — Posted on 2020-02-19

1405 IHS: an integrative method for the identification of network hubs

Salavaty, A.; Ramialison, M.; Currie, P. D.

10.1101/2020.02.17.953430 — systems biology — Posted on 2020-02-19

Groblewski, P. A.; Ollerenshaw, D. R.; Kiggins, J.; Garrett, M. E.; Mochizuki, C.; Casal, L.; Cross, S.; Mace, K.; Swapp, J.; Manavi, S.; Williams, D.; Mihalas, S.; Olsen, S. R.

10.1101/2020.02.18.954990 — neuroscience — Posted on 2020-02-19

1407 Transcription-associated topoisomerase activities control DNA-breaks production by G-quadruplex ligands

Pipier, A.; Bossaert, M.; Riou, J. F.; Noirot, C.; Nguyen, L.-T.; Serre, R. F.; Bouchez, O.; Defrancq, E.; Calsou, P.; Britton, S.; Gomez, D.

10.1101/2020.02.18.953851 — molecular biology — Posted on 2020-02-19

1408 The Gene Expression Profile of Uropathogenic Escherichia coli in Women with Uncomplicated Urinary Tract Infections Is Recapitulated in the Mouse Model

Frick-Cheng, A. E.; Sintsova, A.; Smith, S. N.; Krauthammer, M.; Eaton, K. A.; Mobley, H. L. T.

10.1101/2020.02.18.954842 — microbiology — Posted on 2020-02-19

1409 Exon probe sets and bioinformatics pipelines for all levels of fish phylogenomics

Hughes, L. C.; Orti, G.; Saad, H.; Li, C.; White, W. T.; Baldwin, C. C.; Crandall, K. A.; Arcila, D.; Betancur-R., R.

10.1101/2020.02.18.949735 — evolutionary biology — Posted on 2020-02-19

1410 Endosomes facilitate mitochondrial clearance by enhancing Mfn2 degradation and subsequent Parkin recruitment

Ravindran, R.; Velikkakath, A. K. G.; Narendradev, N. D.; Chandrasekharan, A.; Santhoshkumar, T. R.; Srinivasula, S. M.

10.1101/2020.02.19.955880 — cell biology — Posted on 2020-02-19

1411 "Sulcus Sink": A Compact Binary and Semi-Automated Inverse Dijkstra-based System for Describing Sulcal Trajectories

Pienaar, R.

10.1101/2020.02.18.955096 — bioinformatics — Posted on 2020-02-19

1412 Plant-soil nitrogen, carbon and phosphorus content after the addition of biochar, bacterial inoculums and N fertilizer

Mikajlo, I.; Pourrut, B.; Louvel, B.; Hynst, J.; Zahora, J.

10.1101/2020.02.18.954941 — plant biology — Posted on 2020-02-19

1413 The neural link between subjective value and decision entropy

Bobadilla-Suarez, S.; Guest, O.; Love, B. C.

10.1101/2020.02.18.954362 — neuroscience — Posted on 2020-02-19

1414 Estimation of the number of synapses in the hippocampus and brain-wide by volume electron microscopy and genetic labeling

Santuy, A.; Tomas-Roca, L.; Rodriguez, J.-R.; Gonzalez-Soriano, J.; Zhu, F.; Qiu, Z.; Grant, S. G.; DeFelipe, J.; Merchan-Perez, A.

10.1101/2020.02.18.953802 — neuroscience — Posted on 2020-02-19

1415 Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy

Masson, C.; Garcia-Garcia, D.; Bitard, J.; Grellier, E.; Roger, J. E.; Perron, M.

10.1101/2020.02.18.953943 — neuroscience — Posted on 2020-02-19

1416 The endometrial transcription landscape of MRKH syndrome

Hentrich, T.; Koch, A.; Weber, N.; Kilzheimer, A.; Burkhardt, S.; Rall, K.; Casadei, N.; Kohlbacher, O.; Riess, O.; Schulze-Hentrich, J. M.; Brucker, S. Y.

10.1101/2020.02.18.954768 — genomics — Posted on 2020-02-19

1417 Genome editing enables reverse genetics of multicellular development in the choanoflagellate Salpingoeca rosetta

Booth, D. S.; King, N.

10.1101/2020.02.18.948406 — evolutionary biology — Posted on 2020-02-19

1418 The genomic basis of animal origins: a chromosomal perspective from the sponge Ephydatia muelleri

Kenny, N. J.; Francis, W. R.; Rivera-Vicens, R. E.; Juravel, K.; de Mendoza, A.; Diez-Vives, C.; Lister, R.; Bezares-Calderon, L.; Grombacher, L.; Roller, M.; Barlow, L. D.; Camilli, S.; Ryan, J. F.; Wörheide, G.; Hill, A. L.; Riesgo, A.; Leys, S.

10.1101/2020.02.18.954784 — evolutionary biology — Posted on 2020-02-19

1419 Floating frogs sound larger: environmental constraints on signal production drives call frequency changes

Goutte, S.; Munoz, M. I.; Ryan, M. J.; Halfwerk, W.

10.1101/2020.02.18.953836 — evolutionary biology — Posted on 2020-02-19

1420 Response to Tavares et al., "Covariation analysis with improved parameters reveals conservation in lncRNA structures"

Rivas, E.; Eddy, S. R.

10.1101/2020.02.18.955047 — bioinformatics — Posted on 2020-02-19

1421 Variance-adjusted Mahalanobis (VAM): a fast and accurate method for cell-specific gene set scoring

Frost, H. R.

10.1101/2020.02.18.954321 — bioinformatics — Posted on 2020-02-19

1422 Acoustogenetic Control of CAR T Cells via Focused Ultrasound

WU, Y.; Liu, Y.; Huang, Z.; Wang, X.; Jin, Z.; Li, J.; Limsakul, P.; Zhu, L.; Allen, M.; Pan, Y.; Bussell, R.; Jacobson, A.; Liu, T.; Chien, S.; Wang, Y.

10.1101/2020.02.18.955005 — bioengineering — Posted on 2020-02-19

1423 Emergent properties of the HNF4α-PPARγ may drive consequent phenotypic plasticity in NAFLD

Sahoo, S.; Singh, D.; Chakraborty, P.; Jolly, M. K.

10.1101/2020.02.18.953935 — systems biology — Posted on 2020-02-19

1424 Diastolic Dysfunction Accompanies Alterations in Myocardial Structure, Cellular Composition and Macrophage Polarization in Survivors of Ionizing Radiation Exposure

Michalson, K. T.; Dugan, G. O.; Caudell, D. L.; Kitzman, D. W.; Cline, J. M.; Register, T. C.

10.1101/2020.02.18.953190 — pathology — Posted on 2020-02-19

1425 Distinct representations of finger movement and force in human motor and premotor cortices

Flint, R. D.; Tate, M. C.; Li, K.; Templer, J. W.; Rosenow, J. M.; Pandarinath, C.; Slutzky, M. W.

10.1101/2020.02.18.952945 — neuroscience — Posted on 2020-02-19

1426 Chronic Chemogenetic Manipulation of Ventral Pallidum Targeted Neurons in Rats Fed an Obesogenic Diet.

Doucette, W. T.; Smedley, E. B.; Ruiz-Jaquez, M.; Khokhar, J. Y.; Smith, K.

10.1101/2020.02.18.954677 — neuroscience — Posted on 2020-02-19

1427 Spatiotemporal Dynamics of Orthographic and Lexical Processing in the Ventral Visual Pathway

Woolnough, O.; Donos, C.; Rollo, P. S.; Forseth, K. J.; Lakretz, Y.; Crone, N. E.; Fischer-Baum, S.; Dehaene, S.; Tandon, N.

10.1101/2020.02.18.955039 — neuroscience — Posted on 2020-02-19

1428 Analysis of Circulating Exosomes Reveals a Peripheral Signature of Astrocytic Pathology in Schizophrenia

Ranganathan, M.; Rahman, M.; GANESH, S.; D'Souza, D. C.; Skosnik, P. D.; Radhakrishnan, R.; Pathania, S.; Mohanakumar, T.

10.1101/2020.02.18.955013 — neuroscience — Posted on 2020-02-19

1429 ASH1L REGULATES THE STRUCTURAL DEVELOPMENT OF NEURONAL CIRCUITRY BY MODULATING BDNF/TrkB SIGNALING IN HUMAN NEURONS

Cheon, S. H.; Culver, A. M.; Bagnell, A. M.; Ritchie, F. D.; Clytus, J. M.; McCord, M.; Pappendorp, C. M.; Chukwurah, E.; Smith, A. J.; Cowen, M. H.; Ghate, P. S.; Davis, S. W.; Liu, J. S.; Lizarraga, S.

10.1101/2020.02.18.954586 — neuroscience — Posted on 2020-02-19

1430 An unbiased drug screen for seizure suppressors in Dup15q syndrome reveals 5HT1A and dopamine pathway activation as potential therapies

Roy, B.; Han, J.; Hope, K. A.; Peters, T.; Palmer, G.; Reiter, L.

10.1101/2020.02.18.954560 — neuroscience — Posted on 2020-02-19

1431 The CEPR2-mediated phosphorylation of NRT1.2 mainly regulates ABA import in Arabidopsis

Yu, Z.; Zhang, L.; Xu, Y.; Yu, M.; Zhang, S.; Yang, G.; Huang, J.; Yan, K.; Zheng, C.; Wu, C.

10.1101/2020.02.18.953711 — molecular biology — Posted on 2020-02-19

1432 Development of a honey bee RNA virus vector based on the genome of Deformed wing virus.

Ryabov, E. V.; Christmon, K.; Heerman, M. C.; Posada-Florez, F.; Harrison, R. L.; Chen, Y. P.; Evans, J. D.

10.1101/2020.02.18.954958 — microbiology — Posted on 2020-02-19

1433 A generalizable method for false-discovery rate estimation in mass spectrometry-based lipidomics

Fujimoto, G. M.; Kyle, J. E.; Lee, J.-Y.; Metz, T. O.; Payne, S. H.

10.1101/2020.02.18.946483 — bioinformatics — Posted on 2020-02-19

1434 Investigating the dynamics of microbial consortia in spatially structured environments

Gupta, S.; Ross, T. D.; Gomez, M. M.; Grant, J. L.; Romero, P. A.; Venturelli, O. S.

10.1101/2020.02.17.953240 — systems biology — Posted on 2020-02-19

1435 Integrated in silico and 3D in vitro model of macrophage migration in response to physical and chemical factors in the tumor microenvironment

Lee, S. W. L.; Seager, R. J.; Litvak, F.; Spill, F.; Sieow, J. L.; Penny, H. L.; Kumar, D.; Tan, A. S. M.; Wong, S. C.; Adriani, G.; Zaman, M. H.; Kamm, R. D.

10.1101/2020.02.17.953208 — systems biology — Posted on 2020-02-19

1436 Using computational modeling to teach metabolism as a dynamic system improves student performance

Booth, C. S.; Song, C.; Howell, M. E.; Rasquinha, A.; Saska, A.; Helikar, R.; Sikich, S. M.; Couch, B. A.; van Dijk, K.; Roston, R. L.; Helikar, T.

10.1101/2020.02.18.953380 — scientific communication and education — Posted on 2020-02-19

1437 Anethole dithiolethione improves liver fatty acid metabolism in hamster fed high-fat diets

Zhao, C.; Yu, N.; Li, W.; Cai, H.-L.; Liu, M.; Hu, Y.; Liu, Y.; Tang, M.

10.1101/2020.02.18.954875 — pharmacology and toxicology — Posted on 2020-02-19

1438 Generative modeling of brain maps with spatial autocorrelation

Burt, J. B.; Helmer, M.; Shinn, M.; Anticevic, A.; Murray, J. D.

10.1101/2020.02.18.955054 — neuroscience — Posted on 2020-02-19

1439 Cerebral Atrophy in Amyotrophic Lateral Sclerosis Parallels the Pathological Distribution of TDP43

Dadar, M.; Manera, A.; Zinman, L.; Korngut, L.; Genge, A.; Graham, S.; Frayne, R.; Collins, D. L.; Kalra, S.

10.1101/2020.02.18.954883 — neuroscience — Posted on 2020-02-19

1440 Towards domain-general predictive coding: Expected TMS excites the motor system less effectively than unexpected stimulation

Tran, D. M. D.; McNair, N. A.; Harris, J. A.; Livesey, E. J.

10.1101/2020.02.18.953562 — neuroscience — Posted on 2020-02-19

1441 Discovering and exploiting multiple types of DNA methylation from individual bacteria and microbiome using nanopore sequencing

Tourancheau, A.; Mead, E. A.; Zhang, X.-s.; Fang, G.

10.1101/2020.02.18.954636 — microbiology — Posted on 2020-02-19

1442 A Superfamily of T6SS Antibacterial Effectors Displaying L,D-carboxypeptidase Activity Towards Peptidoglycan

Sibinelli-Sousa, S.; Hespanhol, J. T.; Nicastro, G. G.; Matsuyama, B. Y.; Mesnage, S.; Patel, A.; de Souza, R. F.; Guzzo, C. R.; Bayer-Santos, E.

10.1101/2020.02.18.954545 — microbiology — Posted on 2020-02-19

1443 Genomic variation and population histories of spotted (Strix occidentalis) and barred (S. varia) owls

Fujito, N. T.; Hanna, Z. R.; Levy-Sakin, M.; Bowie, R. C. K.; Kwok, P.-Y.; Dumbacher, J. P.; Wall, J. D.

10.1101/2020.02.18.954685 — evolutionary biology — Posted on 2020-02-19

1444 Fine-tuning of the PAX-SIX-EYA-DACH network by multiple microRNAs controls embryo myogenesis

Viaut, C.; Munsterberg, A.

10.1101/2020.02.18.954446 — developmental biology — Posted on 2020-02-19

1445 MEK inhibition causes Bim stabilization and sensitivity to Bcl2 family member inhibitors in RAS-MAPK mutated neuroblastoma

Eleveld, T. F.; Vernooij, L.; Schild, L.; Koopmans, B.; Alles, L. K.; Ebus, M. E.; van Sluis, P. G.; Caron, H. N.; Koster, J.; Versteeg, R.; Dolman, E. M.; Molenaar, J. J.

10.1101/2020.02.12.945089 — cancer biology — Posted on 2020-02-19

1446 Specific Inhibition of GSK-3β by Tideglusib: Potential Therapeutic Target for Neuroblastoma Cancer Stem Cells

Bahmad, H. F.; Chalhoub, R. M.; Harati, H.; Bou-Gharios, J.; Ballout, F.; Monzer, A.; Msheik, H.; Assi, S.; Araji, T.; Elajami, M. K.; Ghanem, P.; Chamaa, F.; Kadara, H.; Abou-Antoun, T.; Daoud, G.; Fares, Y.; Abou-Kheir, W.

10.1101/2020.02.18.953596 — cancer biology — Posted on 2020-02-19

1447 Compliance with the continuity axiom of Expected Utility Theory supports utility maximization in monkeys

Ferrari-Toniolo, S.; Bujold, P. M.; Grabenhorst, F.; Baez-Mendoza, R.; Schultz, W.

10.1101/2020.02.18.953950 — animal behavior and cognition — Posted on 2020-02-19

1448 The construction and application of a new 17-plex Y-STR system using universal fluorescent PCR

Liu, J.; Wang, R.; Shi, J.; Cheng, X.; Hao, T.; Guo, J.; Wang, J.; Liu, Z.; Li, W.; Fan, H.; Yun, K.; Yan, J.; Zhang, G.

10.1101/2020.02.18.953919 — genetics — Posted on 2020-02-19

1449 Differential Expression and Interaction network construction of Noncoding RNA and mRNA in Heart Tissue associated with Tetralogy of Fallot

Liu, L.; Wang, H.; Cui, C.; Li, Y.; Liu, Y.; Fan, T.; Peng, B.

10.1101/2020.02.18.953877 — genetics — Posted on 2020-02-19

1450 Assessing trait driver theory along abiotic gradients in a tropical plant communities

Lourenco, J.; Newman, E. A.; Enquist, B. J.; Dias Milanez, C. R.; Thomaz, L. D.

10.1101/2020.02.15.950139 — ecology — Posted on 2020-02-19

1451 SEEKING CANDIDATE MOLECULES AS PROGNOSTIC HEALING MARKERS IN CHRONIC VENOUS ULCERS

Cavassan, N. V. R.; Mariani, N. A. P.; Cavassan, C. C.; Wolf, I. R.; Barraviera, B.; Ferreira, R. S.; Valente, G. T.; Silva, E. J. R.; Miot, H. A.; Abbade, L. P. F.; SANTOS, L. D. d. D.

10.1101/2020.02.18.954594 — biochemistry — Posted on 2020-02-19

1452 Efficient coding of numbers explains decision bias and noise

Prat-Carrabin, A.; Woodford, M.

10.1101/2020.02.18.942938 — animal behavior and cognition — Posted on 2020-02-19

1453 Arabidopsis REI-LIKE proteins activate ribosome biogenesis during cold acclimation

Cheong, B. E.; Beine-Golovchuk, O.; Gorka, M.; Ho, W. W. H.; Martinez-Seidel, F.; Firmino, A. A. P.; Skirycz, A.; Roessner, U.; Kopka, J.

10.1101/2020.02.18.954396 — plant biology — Posted on 2020-02-19

1454 Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury

Ettou, S.; Kim, Y. L.; Miyoshi, T.; Jain, D.; Hirasuta, K.; Schumacher, V. A.; Taglienti, M. E.; Morizane, R.; Park, P. J.; Kreidberg, J.

10.1101/2020.02.18.954347 — molecular biology — Posted on 2020-02-19

1455 An Envelope Protein of a Prokaryotic Organelle Function towards Conserving Catalytic Activity of the Native Enzyme at Higher Temperatures

Kumar, G.; Bari, N. K.; Hazra, J. P.; Sinha, S.

10.1101/2020.02.18.954511 — molecular biology — Posted on 2020-02-19

1456 A lipocalin mediates unidirectional haem biomineralization in malaria parasites

Matz, J. M.; Drepper, B.; Blum, T. B.; van Genderen, E.; Burrell, A.; Martin, P.; Stach, T.; Collinson, L.; Abrahams, J. P.; Matuschewski, K.; Blackman, M. J.

10.1101/2020.02.18.954289 — microbiology — Posted on 2020-02-19

1457 Frequency of mispackaging of Prochlorococcus DNA by cyanophage

Raho, N.; Laurenceau, R.; Forget, M.; Arellano, A.; Chisholm, S. W.

10.1101/2020.02.18.953059 — microbiology — Posted on 2020-02-19

1458 Spatial segregation and cooperation in radially expanding microbial colonies under antibiotic stress

Sharma, A.; Wood, K. B.

10.1101/2020.02.18.954644 — microbiology — Posted on 2020-02-19

1459 Mutation bias can shape adaptation in large asexual populations experiencing clonal interference

Gomez, K.; Bertram, J.; Masel, J.

10.1101/2020.02.17.953265 — evolutionary biology — Posted on 2020-02-19

1460 Comparing the fate of brain metastatic breast cancer cells in different immune compromised mice with cellular magnetic resonance imaging

Knier, N. N.; Hamilton, A. M.; Foster, P. J.

10.1101/2020.02.18.954693 — biophysics — Posted on 2020-02-19

1461 BioTracs: A transversal framework for computational workflow standardization and traceability

Abi-Ghanem, J.; Ouattara, D. A.

10.1101/2020.02.16.951624 — bioinformatics — Posted on 2020-02-19

1462 Electrical coupling between chromatophore muscle fibers allows for versatile control of chromatophore expansion in squid.

Liu, Y.-C.; Wang, W.-C.; Grasse, B.

10.1101/2020.02.17.951715 — systems biology — Posted on 2020-02-19

1463 A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae

Daran-Lapujade, P.; Daran, J.-M. G.; Postma, E.; Dashko, S.; Taylor Parkins, S.; van den Broek, M.; van Breemen, L.

10.1101/2020.02.18.954131 — synthetic biology — Posted on 2020-02-19

1464 A geometric and structural approach to the analysis and design of biological circuit dynamics: a theory tailored for synthetic biology

Marken, J. P.; Xiao, F.; Murray, R. M.

10.1101/2020.02.18.953620 — synthetic biology — Posted on 2020-02-19

1465 Deep sequencing of nonenzymatic RNA primer extension

Duzdevich, D.; Carr, C. E.; Szostak, J. W.

10.1101/2020.02.18.955120 — synthetic biology — Posted on 2020-02-19

1466 Highly specific, multiplexed isothermal pathogen detection with fluorescent aptamer readout

Aufdembrink, L. M.; Khan, P.; Gaut, N. J.; Adamala, K. P.; Engelhart, A. E.

10.1101/2020.02.18.954719 — synthetic biology — Posted on 2020-02-19

1467 Trait plasticity and covariance along a continuous soil moisture gradient

Monroe, J. G.; Cai, H.; Des Marais, D. L.

10.1101/2020.02.17.952853 — plant biology — Posted on 2020-02-19

1468 Spatial maps in olfactory cortex during olfactory navigation

Poo, C.; Agarwal, G.; Bonacchi, N.; Mainen, Z. F.

10.1101/2020.02.18.935494 — neuroscience — Posted on 2020-02-19

1469 Input connectivity reveals additional heterogeneity of dopaminergic reinforcement in Drosophila

Otto, N.; Pleijzier, M. W.; Morgan, I. C.; Edmonson-Stait, A. J.; Heinz, K. J.; Stark, I.; Dempsey, G.; Ito, M.; Kapoor, I.; Hsu, J.; Schlegel, P. M.; Bates, A. S.; Costa, M.; Ito, K.; Bock, D. D.; Rubin, G. M.; Jefferis, G. S. X. E.; Waddell, S.

10.1101/2020.02.19.952648 — neuroscience — Posted on 2020-02-19

1470 INFLUENCE OF ENERGY DEFICIENCY ON THE MOLECULAR PROCESSES OF SUBSTANTIA NIGRA PARS COMPACTA CELL FOR UNDERSTANDING PARKINSONIAN NEURODEGENERATION: A COMPREHENSIVE BIOPHYSICAL COMPUTATIONAL MODEL

Muddapu, V. R.; Chakravarthy, V. S.

10.1101/2020.02.18.950337 — neuroscience — Posted on 2020-02-19

1471 Hippocampal GABA-inhibitory circuitry regulates despair-like behavior in mice

Yoon, S. H.; Chung, G.; Song, W. S.; Oh, S. P.; Kim, S. J.; Kim, M.-H.

10.1101/2020.02.18.953786 — neuroscience — Posted on 2020-02-19

1472 Flexible annotation atlas of the mouse brain: combining and dividing brain structures of the Allen Brain Atlas while maintaining anatomical hierarchy

Takata, N.; Sato, N.; Komaki, Y.; Okano, H.; Tanaka, K. F.

10.1101/2020.02.17.953547 — neuroscience — Posted on 2020-02-19

1473 Commonalities and differences in the Oxidative Phosphorylation of Mitochondria and Neuronal Membranes.

Ravera, S.; Bartolucci, M.; Calzia, D.; Morelli, A. M.; Panfoli, I.

10.1101/2020.02.18.953729 — neuroscience — Posted on 2020-02-19

1474 Clustering of CD3ζ is sufficient to initiate T cell receptor signaling

Ma, Y.; Lim, Y. J.; Benda, A.; Goyette, J.; Gaus, K.

10.1101/2020.02.17.953463 — immunology — Posted on 2020-02-19

1475 The stress-induced protein NUPR1 orchestrates protein translation during ER-stress by interacting with eIF2-a

Borrello, M. T.; Santofimia-Castano, P.; Bocchio, M.; Iovanna, J. L.; Pin, C.

10.1101/2020.02.18.954115 — cell biology — Posted on 2020-02-19

1476 Keratins and Plakin family cytolinker proteins control the length of epithelial microridge protrusions

Inaba, Y.; Chauhan, V.; Loon, A. P. v.; Choudhury, L. S.; Sagasti, A.

10.1101/2020.02.18.954933 — cell biology — Posted on 2020-02-19

1477 Differential TM4SF5-mediated SIRT1 modulation and signaling for chronic liver disease

Ryu, J.; Kim, E. M.; Kang, M.; Song, D.-G.; Shin, E.-A.; Jung, J. W.; Nam, S.-H.; Kim, J. E.; Kim, H.-J.; Lee, J.-H.; Yoon, J.-H.; Son, T.; Kim, S.; Kim, H. Y.; Lee, J. W.

10.1101/2020.02.19.956151 — cell biology — Posted on 2020-02-19

1478 Hand-reared wolves show similar, or stronger, attachment toward human caregivers compared to hand-reared dogs

Hansen Wheat, C.; Larsson, L.; Temrin, H.

10.1101/2020.02.17.952663 — animal behavior and cognition — Posted on 2020-02-19

1479 Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

Hillary, R. F.; Trejo-Banos, D.; Kousathanas, A.; McCartney, D. L.; Harris, S. E.; Stevenson, A. J.; Patxot, M.; Ojavee, S. E.; Zhang, Q.; Liewald, D. C.; Ritchie, C. W.; Evans, K. L.; Tucker-Drob, E. M.; Wray, N. R.; McRae, A. F.; Visscher, P. M.; Deary, I. J.; Robinson, M. R.; Marioni, R. E.

10.1101/2020.02.17.952135 — genomics — Posted on 2020-02-19

1480 An alternative miRISC targeting a coding mutation site in FOXL2 links to granulosa cell tumor

Bae, J.; Shin, E.; Jin, H.; Suh, D.-S.; Luo, Y.; Ha, H.-J.; Kim, T. H.; Hahn, Y.; Hyun, S.; Lee, K.

10.1101/2020.02.18.954487 — cancer biology — Posted on 2020-02-19

1481 Identification of characteristic genomic markers in human hepatoma Huh7 and Huh7.5.1-8 cell lines

Kawamoto, M.; Yamaji, T.; Saito, K.; Endo, T.; Fukasawa, M.; Hanada, K.; Osada, N.

10.1101/2020.02.17.953281 — genomics — Posted on 2020-02-19

1482 Thioesterase Superfamily Member 1 Undergoes Stimulus-coupled Reorganization to Regulate Metabolism

Li, Y.; Imai, N.; Goyal, S.; Nicholls, H. T.; Krisko, T. I.; Baqai, M.; Ang, L.-H.; Tillman, M. C.; Ortlund, E. A.; Cohen, D. E.; Hagen, S. J.

10.1101/2020.02.18.954818 — cell biology — Posted on 2020-02-19

1483 Non-invasive real-time imaging of reactive oxygen species (ROS) using multispectral auto-fluorescence imaging technique: a novel tool for redox biology

Habibalahi, A.; Dashtbani Moghari, M.; Campbell, J.; Anwer, A.; Mahbub, S.; Gosnell, M.; saad, s.; Pollock, C.; Goldys, E.

10.1101/2020.02.18.955112 — cell biology — Posted on 2020-02-19

1484 Customizable Live-Cell Imaging Chambers for Fluorescence and Super-Resolution Microscopy.

Tepperman, A. L.; Zheng, D. J.; Abou Taka, M.; Vrieze, A.; Heit, B.

10.1101/2020.02.19.955971 — cell biology — Posted on 2020-02-19

1485 Clinically oriented system-based embryology; a significant course in clinical practice

Moghadam, S.; Gharebaghi, H.; Mohamadi, M. J.; Farokhi, A.; Ghorbanlou, M.; Arianmanesh, M.

10.1101/2020.02.13.946988 — scientific communication and education — Posted on 2020-02-19

1486 Disadvantages of writing, reading, publishing and presenting scientific papers caused by the dominance of the English language in science: The case of Colombian Ph.D. in biological sciences

Ramirez-Castaneda, V.

10.1101/2020.02.15.949982 — scientific communication and education — Posted on 2020-02-19

1487 Leveraging prior concept learning improves ability to generalize from few examples in computational models of human object recognition

Rule, J.; Riesenhuber, M.

10.1101/2020.02.18.944702 — neuroscience — Posted on 2020-02-19

1488 Identifying candidate detoxification genes in the ecdysteroid kinase-like (EcKL) and cytochrome P450 gene families in Drosophila melanogaster by integrating evolutionary and transcriptomic data

Scanlan, J. L.; Gledhill-Smith, R. S.; Battlay, P.; Robin, C.

10.1101/2020.02.17.951962 — genetics — Posted on 2020-02-19

1489 Height differences in clonal stands of Tussilago farfara promote outcrossing by influencing pollinator behaviour

Dolezal, A. J.

10.1101/2020.02.17.952713 — ecology — Posted on 2020-02-19

1490 Functional Ensemble Survival Tree: Dynamic Prediction of Alzheimer's Disease Progression Accommodating Multiple Time-Varying Covariates

Jiang, S.; Xie, Y.; Colditz, G. A.

10.1101/2020.02.17.952994 — bioinformatics — Posted on 2020-02-19

1491 Elongation index as a sensitive measure of cell deformation in high-throughput microfluidic systems

Hymel, S. J.; Lan, H.; Khismatullin, D. B.

10.1101/2020.02.17.953323 — bioengineering — Posted on 2020-02-19

1492 Cystin gene mutations cause autosomal recessive polycystic kidney disease associated with altered Myc expression

Yang, C.; OConnor, A. K.; Kesterson, R. A.; Watts, J. A.; Majmundar, A. M.; Lek, M.; Braun, D. A.; Laricchia, K. M.; Fathy, H. M.; Shril, S.; Hildebrandt, F.; Guay-Woodford, L. M.

10.1101/2020.02.18.946285 — molecular biology — Posted on 2020-02-19

1493 Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution

Ramayo-Caldas, Y.; Prenafeta, F.; Zingaretti, L. M.; Gonzales, O.; Dalmau, A.; Quintanilla, R.; Ballester, M.

10.1101/2020.02.18.941856 — genomics — Posted on 2020-02-19

1494 Extensive genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm

Doyle, S. R.; Tracey, A.; Laing, R.; Holroyd, N.; Bartley, D.; Bazant, W.; Beasley, H.; Beech, R.; Britton, C.; Brooks, K.; Maitland, K.; Martinelli, A.; Noonan, J. D.; Paulini, M.; Quail, M. A.; Redman, E.; Rodgers, F. H.; Salle, G.; Sankaranarayanan, G.; Howe, K. L.; Sargison, N.; Devaney, E.; Berriman, M.; Gilleard, J. S.; Cotton, J. A.

10.1101/2020.02.18.945246 — genomics — Posted on 2020-02-19

1495 A whole-genome sequenced control population in northern Sweden reveals subregional genetic differences.

Svensson, D.; Rentoft, M.; Dahlin, A. M.; Lundholm, E.; Olason, P. I.; Sjodin, A.; Nylander, C.; Melin, B. S.; Trygg, J.; Johansson, E.

10.1101/2020.02.18.933622 — genetics — Posted on 2020-02-19

1496 Urethral luminal epithelia are castration-insensitive progenitors of the proximal prostate

10.1101/2020.02.19.937615 — cell biology — Posted on 2020-02-19

1497 Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differential modulation of ABC transporters on chronic myeloid leukemias

Salustiano, E. J.; da Costa, K. M.; Freire-de-Lima, L.; Mendonca-Previato, L.; Previato, J. O.

10.1101/2020.02.18.954297 — cancer biology — Posted on 2020-02-19

1498 Molecular mechanism for direct actin force-sensing by α-catenin

Mei, L.; Espinosa de los Reyes, S.; Reynolds, M. J.; Liu, S.; Alushin, G. M.

10.1101/2020.02.18.954735 — biophysics — Posted on 2020-02-19

1499 Comparison of three glycoproteomic methods for the analysis of CHO cells treated with 1,3,4-O-Bu3ManNAc

Mertz, J. L.; Sun, S.; Yin, B.; Betenbaugh, M. J.; Yarema, K. J.; Zhang, H.

10.1101/2020.02.18.954198 — biochemistry — Posted on 2020-02-19

1500 Neural network features distinguish chemosensory stimuli in Caenorhabditis elegans.

How, J. J.; Navlakha, S.; Chalasani, S. H.

10.1101/2020.02.18.955245 — neuroscience — Posted on 2020-02-19

1501 Antimicrobial silver inhibits bacterial movement and stalls flagellar motor

Russell, B.; Rogers, A.; Kurilich, M.; Krishnamurthi, V. R.; Chen, J.; Wang, Y.

10.1101/2020.02.19.956201 — biophysics — Posted on 2020-02-19

1502 The intriguing dynamics of chromatin folding and assembly

Yang, Z.; Miao, W.; Mofrad, M. R. K.

10.1101/2020.02.18.953398 — biophysics — Posted on 2020-02-19

1503 Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

Kirchdoerfer, R.; Bhandari, M.; Martini, O.; Sewell, L. M.; Bangaru, S.; Yoon, K.-J.; Ward, A.

10.1101/2020.02.18.955195 — biophysics — Posted on 2020-02-19

1504 O-GlcNAcylation and oxidation contribute to atrial fibrillation in diabetes by activating CaMKII

10.1101/2020.02.18.954909 — molecular biology — Posted on 2020-02-19

1505 Visualizing tumour self-homing with magnetic particle imaging

Parkins, K. M.; Melo, K. P.; Ronald, J. A.; Foster, P. J.

10.1101/2020.02.17.953232 — biophysics — Posted on 2020-02-19

1506 Plasmon-Coupled Photocapacitor Neuromodulators

Melikov, R.; Srivastava, S. B.; Karatum, O.; Dogru, I. B.; Bahmani Jalali, H.; Sadeghi, S.; Dikbas, U. M.; Ulgut, B.; Kavakli, I. H.; Nizamoglu, S.

10.1101/2020.02.18.953604 — biophysics — Posted on 2020-02-19

1507 Bent DNA bows as amplifiers and biosensors for detecting DNA-interacting salts and molecules

Freeland, J.; Zhang, L.; Wang, S.-T.; Ruiz, M.; Wang, Y.

10.1101/2020.02.19.956144 — biophysics — Posted on 2020-02-19

1508 Adolescent Social Isolation Reprograms the Medial Amygdala: Transcriptome and Sex Differences in Reward

Walker, D. M.; Zhao, X.; Ramakrishnan, A.; Cates, H. M.; Cunningham, A. M.; Pena, C. J.; Bagot, R. C.; Issler, O.; Van der Zee, Y.; Lipschultz, A. P.; Godino, A.; Browne, C. J.; Hodes, G. E.; Parise, E. M.; Torres-Berrio, A.; Kennedy, P. J.; Shen, L.; Zhang, B.; Nestler, E. J.

10.1101/2020.02.18.955187 — neuroscience — Posted on 2020-02-19

1509 Pupil dilation is sensitive to semantic ambiguity and acoustic degradation

Kadem, M.; Herrmann, B.; Rodd, J. M.; Johnsrude, I. S.

10.1101/2020.02.19.955609 — neuroscience — Posted on 2020-02-19

1510 Localized activation of ependymal progenitors induces EMT-mediated glial bridging after spinal cord injury

Zhou, L.; Burris, B.; Mcadow, R.; Mokalled, M. H.

10.1101/2020.02.18.955401 — neuroscience — Posted on 2020-02-19

1511 Prediction of Essential Binding Domains for the Endocannabinoid N-Arachidonoylethanolamine (AEA) in the Brain Cannabinoid CB1 receptor

Shim, J.

10.1101/2020.02.19.956003 — neuroscience — Posted on 2020-02-19

1512 Striatal direct and indirect pathway neurons differentially control the encoding and updating of goal-directed learning.

Peak, J.; Chieng, B.; Hart, G.; Balleine, B. W.

10.1101/2020.02.18.955385 — neuroscience — Posted on 2020-02-19

1513 Multiple timescales of neural dynamics and integration of task-relevant signals across cortex

Spitmaan, M. M.; Seo, H.; Lee, D.; Soltani, A.

10.1101/2020.02.18.955427 — neuroscience — Posted on 2020-02-19

1514 Ras-GRF1 in CRF Cells Controls the Early Adolescent Female Response to Repeated Stress

Jin, S.-X.; Dickson, D. A.; Maguire, J.; Feig, L.

10.1101/2020.02.19.955088 — neuroscience — Posted on 2020-02-19

1515 Sex moderates the relationship between aortic stiffness, cognition and cerebrovascular reactivity in healthy older adults

Sabra, D.; intzandt, b.; Desjardins-Crepeau, L.; Langeard, A.; Steele, C. J.; Frouin, F.; Hoge, R. D.; Bherer, L.; Gauthier, C. J.

10.1101/2020.02.18.955146 — neuroscience — Posted on 2020-02-19

1516 Energy-based models to describe complex neuronal activities and metabolic constraints

Fardet, T.; Levina, A.

10.1101/2020.02.19.955898 — neuroscience — Posted on 2020-02-19

1517 Increasing muscle speed drives changes in the neuromuscular transform of motor commands during postnatal development in songbirds

Adam, I.; Elemans, C. P.

10.1101/2020.02.19.955799 — neuroscience — Posted on 2020-02-19

1518 A machine-vision approach for automated pain measurement at millisecond timescales

Jones, J.; Foster, W.; Twomey, C.; Burdge, J.; Ahmed, O.; Wojick, J. A.; Corder, G.; Plotkin, J. B.; Abdus-Saboor, I.

10.1101/2020.02.18.955070 — neuroscience — Posted on 2020-02-19

1519 Fast retrograde access to projection neuron circuits underlying vocal learning in songbirds

During, D. N.; Dittrich, F.; Rocha, M. D.; Tachibana, R.; Mori, C.; Okanoya, K.; Boehringer, R.; Ehret, B.; Grewe, B.; Rauch, M.; Paterna, J.-C.; Kasper, R.; Gahr, M.; Hahnloser, R. H.

10.1101/2020.02.19.955773 — neuroscience — Posted on 2020-02-19

1520 Live cell imaging of single neurotrophin receptor molecules on human neuron in Alzheimer's disease

Barabas, K.; Kobolak, J.; Godo, S.; Ernszt, D.; Kecskes, M.; Varga, C.; Kardos, J.; Janosi, T.; Fujiwara, T.; Kusumi, A.; Teglasi, A.; Dinnyes, A.; Abraham, I.

10.1101/2020.02.17.953174 — neuroscience — Posted on 2020-02-19

1521 Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam

Lam, T. T.; Toffaletti, D.; Tenor, J.; Giamberardino, C.; Sempowski, G.; Asfaw, Y.; Phan, T. H.; Duong, A. V.; Nguyen, T. M.; Nguyen, L. P. H.; Tran, C. T. H.; Ashton, P. M.; Beardsley, J.; Nguyen, C. V. V.; Thwaites, G. E.; Baker, S.; Perfect, J. R.; Day, J. N.

10.1101/189274 — microbiology — Posted on 2020-02-19

1522 A Universal Law of Sensory Adaptation

Wong, W.

10.1101/2020.02.17.953448 — neuroscience — Posted on 2020-02-19

1523 Semantic segmentation of microscopic neuroanatomical data by combining topological priors with encoder-decoder deep networks

Banerjee, S.; Magee, L.; Wang, D.; Li, X.; Huo, B.-X.; Jayakumar, J.; Matho, K.; Lin, M.-K.; Ram, K.; Sivaprakasam, M.; Huang, Z. J.; Wang, Y.; Mitra, P. P.

10.1101/2020.02.18.955237 — neuroscience — Posted on 2020-02-19

1524 An anatomical substrate of credit assignment in reinforcement learning

Kornfeld, J. M.; Januszewski, M.; Schubert, P. J.; Jain, V.; Denk, W.; Fee, M. S.

10.1101/2020.02.18.954354 — neuroscience — Posted on 2020-02-19

1525 Altered patterning of interneuron progenitors in Down syndrome

Giffin-Rao, Y.; Strand, B.; Huang, L.; Medo, M.; Levesque, B.; Daley, R. A.; Amundson, L.; Keshan, A.; Reese, R.; Wang, D.; Zhang, S.-C.; Bhattacharyya, A.

10.1101/2020.02.18.951756 — developmental biology — Posted on 2020-02-19

1526 RASA1-driven cellular export of collagen IV is required for the development of lymphovenous and venous valves in mice

Chen, D.; Geng, X.; Lapinski, P. E.; Davis, M. J.; Srinivasan, R. S.; King, P. D.

10.1101/2020.02.17.953364 — developmental biology — Posted on 2020-02-19

1527 Impact of gestational low-protein intake on embryonic kidney microRNA expression and in the nephron progenitor cells of the male offspring fetus

Gontijo, J.; de Barros Sene, L.; Boer, P. A.; Lopes-Cendes, I.; Zapparoli, A.; Scarano, W. R.

10.1101/2020.02.18.954800 — developmental biology — Posted on 2020-02-19

1528 Management, Analyses, and Distribution of the MaizeCODE Data on the Cloud

Wang, L.

10.1101/852269 — bioinformatics — Posted on 2020-02-19

1529 Sepsis-associated Pathways Segregate Cancer Groups

Tripathi, H.; Mukhopadhyay, S.; Mohapatra, S. K.

10.1101/635243 — genomics — Posted on 2020-02-19

1530 Diet-induced changes to host gut microbiota are linked to foraging innovation in a wild bird.

Davidson, G.; Wiley, N.; Cooke, A. C.; Johnson, C. N.; Fouhy, F.; Reichert, M. S.; de la Hera, I.; Crane, J. M. S.; Kulahci, I. G.; Ross, R. P.; Stanton, C.; Quinn, J. L.

10.1101/827741 — ecology — Posted on 2020-02-19

1531 Bid as a novel interacting partner of IRE1 differentially regulating its RNAse activity

Bashir, S.; Pal, D.; Banday, M.; Qadri, O.; Bashir, A.; Hazari, Y. M.; Hilal, N.; Altaf, M.; Fazili, K. M.

10.1101/572222 — cell biology — Posted on 2020-02-19

1532 Improved prediction of MHC II antigen presentation throughintegration and motif deconvolution of mass spectrometryMHC eluted ligand data

Reynisson, B.; Barra, C.; Kaabinejadian, S.; Hildebrand, W. H.; Peters, B.; Nielsen, M.

10.1101/799882 — bioinformatics — Posted on 2020-02-19

1533 Human labor pain is influenced by the voltage-gated potassium channel KV6.4 subunit

Lee, M. C.; Nahorski, M.; Hockley, J. R. F.; Lu, V. B.; Ison, G.; Pattison, L.; Callejo, G.; Stouffer, K.; Fletcher, E.; Brown, C.; Drissi, I.; Wheeler, D.; Ernfors, P.; Menon, D. K.; Reimann, F.; St John Smith, E.; Woods, C. G.

10.1101/489310 — neuroscience — Posted on 2020-02-19

1534 Common fragile sites are characterised by faulty condensin loading after replication stress

Boteva, L.; Nozawa, R.-S.; Naughton, C.; Samejima, K.; Earnshaw, W.; Gilbert, N.

10.1101/508713 — molecular biology — Posted on 2020-02-19

1535 Long-term experimental evolution reveals purifying selection on piRNA-mediated control of transposable element expression

Bergthorsson, U.; Sheeba, C. J.; Konrad, A.; Belicard, T.; Beltran, T.; Katju, V.; Sarkies, P.

10.1101/666693 — molecular biology — Posted on 2020-02-19

1536 Genomic potential for photoferrotrophy in a seasonally anoxic Boreal Shield lake

Tsuji, J. M.; Tran, N.; Schiff, S. L.; Venkiteswaran, J. J.; Molot, L. A.; Tank, M.; Hanada, S.; Neufeld, J. D.

10.1101/653014 — microbiology — Posted on 2020-02-19

1537 Escherichia ruysiae sp. nov., isolated from an international traveller

van der Putten, B. C.; Matamoros, S.; Mende, D. R.; COMBAT Consortium, ; Schultsz, C.

10.1101/781724 — microbiology — Posted on 2020-02-19

1538 Genome variation and population structure among 1,142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii

Clarkson, C. S.; Miles, A.; Harding, N. J.; Lucas, E. R.; Battey, C. J.; Amaya-Romero, J. E.; Cano, J.; Diabate, A.; Constant, E.; Nwakanma, D. C.; Jawara, M.; Essandoh, J.; Dinis, J.; Le Goff, G.; Robert, V.; Troco, A. D.; Costantini, C.; Rohatgi, K. R.; Elissa, N.; Coulibaly, B.; Midega, J.; Mbogo, C.; Mawejje, H. D.; Stalker, J.; Rockett, K. A.; Drury, E.; Mead, D.; Jeffreys, A. E.; Hubbart, C.; Rowlands, K.; Isaacs, A. T.; Jyothi, D.; Malangone, C.; Kamali, M.; Henrichs, C.; Simpson, V.; Ayala, D.; Besansky, N. J.; Burt, A.; Caputo, B.; della Torre, A.; Fontaine, M.; Godfray, H. C. J.; Hah

10.1101/864314 — genomics — Posted on 2020-02-19

1539 Bacteria primed by antimicrobial peptides develop tolerance and persist

Rodriguez Rojas, A.; Baeder, D. Y.; Johnston, P. R.; Regoes, R. R.; Rolff, J.

10.1101/802207 — evolutionary biology — Posted on 2020-02-19

1540 Id proteins promote a cancer stem cell phenotype in triple negative breast cancer via negative regulation of Robo1

Teo, W. S.; Holliday, H.; Karthikeyan, N.; Cazet, A. S.; Roden, D. L.; Harvey, K.; Konrad, C. V.; Murali, R.; Varghese, B. A.; T., A. P.; Chan, C.-L.; McFarland, A.; Junankar, S.; Ye, S.; Yang, J.; Nikolic, I.; Shah, J. S.; Baker, L. A.; Millar, E. K. A.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Kaplan, W.; Mellick, A. S.; O'Toole, S. A.; Swarbrick, A.; Nair, R.

10.1101/497313 — cancer biology — Posted on 2020-02-19

1541 Laboratory Evolution Experiments Help Identify a Predominant Region of ΔrnhA-dnaA Constitutive Stable DNA Replication Initiation

Veetil, R. T.; Malhotra, N.; Dubey, A.; Seshasayee, A. S. N.

10.1101/757963 — genomics — Posted on 2020-02-19

1542 Coupling chromatin structure and dynamics by live super-resolution imaging

Barth, R.; Bystricky, K.; Shaban, H.

10.1101/777482 — biophysics — Posted on 2020-02-19

1543 Serotonergic modulation of visual neurons in Drosophila melanogaster

Myers Gschweng, K. M.; Sampson, M. M.; Hardcastle, B. J.; Bonanno, S. L.; Sizemore, T. R.; Arnold, R. C.; Gao, F.; Dacks, A. M.; Frye, M. A.; Krantz, D. E.

10.1101/619759 — neuroscience — Posted on 2020-02-19

1544 Decomposing neural responses to melodic surprise in musicians and non-musicians: evidence for a hierarchy of predictions in the auditory system

Quiroga-Martinez, D. R.; Hansen, N. C.; Hoejlund, A.; Pearce, M. T.; Brattico, E.; Vuust, P.

10.1101/786574 — neuroscience — Posted on 2020-02-19

1545 Bias from competing risk before recruitment in Mendelian Randomization studies of conditions with shared etiology

Schooling, C. M.; Lopez, P. M.; Yang, Z.; Au Yeung, S.; Huang, J. V.

10.1101/716621 — genetics — Posted on 2020-02-19

1546 Speciation and gene flow across an elevational gradient in New Guinea kingfishers

Linck, E.; Freeman, B. G.; Dumbacher, J. P.

10.1101/589044 — evolutionary biology — Posted on 2020-02-19

1547 The transfer of a mitochondrial selfish element to the nuclear genome and its consequences

Dutheil, J. Y.; Münch, K.; Schotanus, K.; Stukenbrock, E. H.; Kahmann, R.

10.1101/787044 — evolutionary biology — Posted on 2020-02-19

1548 Hi-D: Nanoscale mapping of nuclear dynamics in single living cells

Shaban, H. A.; Barth, R.; Bystricky, K.

10.1101/405969 — biophysics — Posted on 2020-02-19

1549 LTP induction boosts glutamate spillover by driving withdrawal of astroglia

Henneberger, C.; Bard, L.; Panatier, A.; Reynolds, J. P.; Kopach, O.; Medvedev, N. I.; Minge, D.; Herde, M. K.; Anders, S.; Kraev, I.; Heller, J.; Rama, S.; Zheng, K.; Jensen, T. P.; Sanchez-Romero, I.; Jackson, C. J.; Janovjak, H.; Ottersen, O.-P.; Nagelhus, E.-A.; Oliet, S. H. R.; Stewart, M. G.; Nagerl, U. V.; Rusakov, D. A.

10.1101/349233 — neuroscience — Posted on 2020-02-19

1550 PCR procedures to amplify GC-rich DNA sequences of Mycobacterium bovis

Assal, N.; Lin, M.

10.1101/2020.02.18.953695 — molecular biology — Posted on 2020-02-18

1551 Estimating voluntary and involuntary attention in bistable visual perception: A MEG study

Chholak, P.; Maksimenko, V. A.; Hramov, A. E.; Pisarchik, A. N.

10.1101/2020.02.18.953653 — neuroscience — Posted on 2020-02-18

1552 Genetic diversity of the spinach downy mildew pathogen based on hierarchical sampling

Feng, C.; Lamour, K.; Dhillon, B. D. S.; Villarroel-Zeballos, M. I.; Castroagudin, V. L.; Bluhm, B. H.; Shi, A.; Rojas, A.; Correll, J. C.

10.1101/2020.02.18.953661 — microbiology — Posted on 2020-02-18

1553 Non-apoptotic Role of Cleaved Caspase-3 in Rat Male Germ Cell Development

Stumpp, T.; Nunes, M.; Arantes, A. D.; Tesser, R. B.; Henriques da Silva, P.; Rocha da Silva, L.; de Oliva, S. U.; Popi, A. F.

10.1101/2020.02.18.953646 — developmental biology — Posted on 2020-02-18

1554 The PP2A/4/6 subfamily of phosphoprotein phosphatases regulates DAF-16 during aging and confers resistance to environmental stress in postreproductive adult C. elegans

Rivard, R. S.; Morris, J. M.; Youngman, M. J.

10.1101/2020.02.18.953687 — genetics — Posted on 2020-02-18

1555 ErrorX: automated error correction for immune repertoire sequencing datasets

Sevy, A. M.

10.1101/2020.02.17.952408 — bioinformatics — Posted on 2020-02-18

1556 Inpainting as a Technique for Estimation of Missing Voxels in Chemical Shift Imaging

Torrado-Carvajal, A.; Albrecht, D. S.; Lee, J.; Andronesi, O. C.; Ratai, E.-M.; Napadow, V.; Loggia, M. L.

10.1101/2020.02.17.952325 — bioengineering — Posted on 2020-02-18

1557 Autonomic arousal tracks outcome salience not valence in monkeys making social decisions

Basile, B. M.; Joiner, J. A.; Dal Monte, O.; Fagan, N. A.; Karaskiewicz, C. L.; Lucas, D. R.; Chang, S. W. C.; Murray, E. A.

10.1101/2020.02.17.952986 — animal behavior and cognition — Posted on 2020-02-18

1558 The effects of microcystin-LR in Oryza sativa root cells: F-actin as a new target of cyanobacterial toxicity

Pappas, D.; Gkelis, S.; Panteris, E.

10.1101/2020.02.17.952218 — plant biology — Posted on 2020-02-18

1559 Sleep and Diurnal Rest-Activity Rhythm Disturbances in a Mouse Model of Alzheimer's Disease

Filon, M. J.; Wallace, E.; Wright, S.; Douglas, D.; Steinberg, L.; Verkuilen, C.; Westmark, P.; Maganti, R.; Westmark, C. J.

10.1101/2020.02.17.950600 — neuroscience — Posted on 2020-02-18

1560 Basal forebrain-derived acetylcholine encodes valence-free reinforcement prediction error.

Sturgill, J. F.; Hegedüs, P.; Li, S.; Chevy, Q.; Siebels, A.; Jing, M.; Li, Y.; Hangya, B.; Kepecs, A.

10.1101/2020.02.17.953141 — neuroscience — Posted on 2020-02-18

1561 Building a high-quality reference genome assembly for the the eastern Mediterranean Sea invasive sprinter Lagocephalus sceleratus (Tetraodontiformes, Tetraodontidae)

Danis, T.; Tsakogiannis, A.; Kristoffersen, J. B.; Golani, D.; Tsaparis, D.; Kasapidis, P.; Kotoulas, G.; Magoulas, A.; Tsigenopoulos, C. S.; Manousaki, T.

10.1101/2020.02.17.952580 — genomics — Posted on 2020-02-18

1562 Learning polygenic scores for human blood cell traits

Xu, Y.; Vuckovic, D.; Ritchie, S. C.; Akbari, P.; Jiang, T.; Grealey, J.; Butterworth, A. S.; Ouwehand, W. H.; Roberts, D. J.; Angelantonio, E. D.; Danesh, J.; Soranzo, N.; Inouye, M.

10.1101/2020.02.17.952788 — genetics — Posted on 2020-02-18

1563 Phylogenetic relatedness, co-occurrence, and rhizomes increase lateral gene transfer among grasses

Hibdige, S. G. S.; Raimondeau, P.; Christin, P.-A.; Dunning, L. T.

10.1101/2020.02.17.952150 — evolutionary biology — Posted on 2020-02-18

1564 Heterotrophic Carbon Fixation in a Salamander-Alga Symbiosis.

Burns, J. A.; Kerney, R.; Duhamel, S.

10.1101/2020.02.14.948299 — ecology — Posted on 2020-02-18

1565 phyr: An R package for phylogenetic species-distribution modelling in ecological communities

Li, D.; Dinnage, R.; Nell, L. A.; Helmus, M. R.; Ives, A. R.

10.1101/2020.02.17.952317 — ecology — Posted on 2020-02-18

1566 CaptureCompendium: a comprehensive toolkit for 3C analysis.

Telenius, J. M.; Downes, D.; Sergeant, M.; Oudelaar, A. M.; McGowan, S.; Kerry, J.; Hanssen, L. L. P.; Schwessinger, R.; Eijsbouts, C. Q.; Davies, J. O. J.; Taylor, S.; Hughes, J. R.

10.1101/2020.02.17.952572 — bioinformatics — Posted on 2020-02-18

1567 RECRUITMENT OF UPPER-LIMB MOTONEURONS WITH EPIDURAL ELECTRICAL STIMULATION OF THE PRIMATE CERVICAL SPINAL CORD

Greiner, N.; Barra, B.; Schiavone, G.; James, N.; Falleger, F.; Borgognon, S.; Lacour, S.; Bloch, J.; Courtine, G.; Capogrosso, M.

10.1101/2020.02.17.952796 — bioengineering — Posted on 2020-02-18

1568 Structural modeling of 2019-novel coronavirus (nCoV) spike protein reveals a proteolytically-sensitive activation loop as a distinguishing feature compared to SARS-CoV and related SARS-like coronaviruses

Jaimes, J. A.; Andre, N. M.; Millet, J. K.; Whittaker, G. R.

10.1101/2020.02.10.942185 — microbiology — Posted on 2020-02-18

1569 Recombination and convergent evolution led to the emergence of 2019 Wuhan coronavirus

Patino-Galindo, J. A.; Filip, I.; AlQuraishi, M.; Rabadan, R.

10.1101/2020.02.10.942748 — evolutionary biology — Posted on 2020-02-18

1570 Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China

Lam, T. T.-Y.; Shum, M. H.-H.; Zhu, H.-C.; Tong, Y.-G.; Ni, X.-B.; Liao, Y.-S.; Wei, W.; Cheung, W. Y.-M.; Li, W.-J.; Li, L.-F.; Leung, G. M.; Holmes, E. C.; Hu, Y.-L.; Guan, Y.

10.1101/2020.02.13.945485 — microbiology — Posted on 2020-02-18

1571 Single-cell Analysis of ACE2 Expression in Human Kidneys and Bladders Reveals a Potential Route of 2019-nCoV Infection

Lin, W.; Hu, L.; Zhang, Y.; Ooi, J. D.; Meng, T.; Jin, P.; Ding, X.; Peng, L.; Song, L.; Xiao, Z.; Ao, X.; Xiao, X.; Zhou, Q.; Xiao, P.; Fan, J.; Zhong, Y.

10.1101/2020.02.08.939892 — genomics — Posted on 2020-02-18

1572 The Photoconvertible Fluorescent Probe, CaMPARI, Labels Active Neurons in Freely-Moving Intact Adult Fruit Flies

Edwards, K. A.; Hoppa, M. B.; Bosco, G.

10.1101/2020.02.18.954669 — neuroscience — Posted on 2020-02-18

1573 Molecular Modeling Evaluation of the Binding Effect of Ritonavir, Lopinavir and Darunavir to Severe Acute Respiratory Syndrome Coronavirus 2 Proteases

Lin, S.; Shen, R.; He, J.; Li, X.; Guo, X.

10.1101/2020.01.31.929695 — biochemistry — Posted on 2020-02-18

1574 A Legionella effector kinase is activated by host inositol hexakisphosphate

Sreelatha, A.; Nolan, C.; Park, B. C.; Pawlowski, K.; Tomchick, D. R.; Tagliabracci, V. S.

10.1101/2020.02.18.954925 — biochemistry — Posted on 2020-02-18

1575 Rapid learning of the 5-choice serial reaction time task in an automated rodent training system

Birtalan, E.; Banhidi, A.; Sanders, J. I.; Balazsfi, D.; Hangya, B.

10.1101/2020.02.16.951491 — neuroscience — Posted on 2020-02-18

1576 GADL1 is a multifunctional decarboxylase with tissue specific roles in β-alanine and carnosine production

Mahootchi, E.; Himaei, S. C.; Kleppe, R.; Winge, I.; Hegvik, T.-A.; Megias-Perez, R.; Totland, C.; Mogavero, F.; Baumann, A.; Glennon, J.; Miletic, H.; Kursula, P.; Haavik, J.

10.1101/2020.02.18.954438 — neuroscience — Posted on 2020-02-18

1577 Microbial redox activity mediated anaerobic pyrite oxidation under circumneutral conditions

Liu, T.; Hu, Y.; Chen, N.; Ma, L.; He, Q.; Feng, C.

10.1101/2020.02.17.952168 — microbiology — Posted on 2020-02-18

1578 Live cell imaging of the hyperthermophilic archaeon Sulfolobus acidocaldarius identifies complementary roles for two ESCRTIII homologues in ensuring a robust and symmetric cell division

Pulschen, A. A.; Mutavchiev, D. R.; Sebastian, K. N.; Roubinet, J.; Roubinet, M.; Risa, G. T.; Wolferen, M. v.; Roubinet, C.; Culley, S.; Dey, G.; Alberts, S.-V.; Henriques, R.; Baum, B.

10.1101/2020.02.18.953042 — microbiology — Posted on 2020-02-18

1579 Microbial Stimulation Reverses the Age-Related Decline in M Cells in Aged Mice

Donaldson, D. S.; Pollock, J.; Vohra, P.; Stevens, M. P.; Mabbott, N. A.

10.1101/2020.02.17.943514 — immunology — Posted on 2020-02-18

1580 Assortative mating and within-spouse pair comparisons

Howe, L. J.; Battram, T.; Morris, T. T.; Hartwig, F. P.; Hemani, G.; Davies, N. M.; Davey Smith, G.

10.1101/2020.02.17.949347 — genetics — Posted on 2020-02-18

1581 Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism

Gaubitz, C.; Liu, X.; Magrino, J.; Stone, N. P.; Landeck, J.; Hedglin, M.; Kelch, B. A.

10.1101/2020.02.18.953257 — biochemistry — Posted on 2020-02-18

1582 Generation and application of river network analogues for use in ecology and evolution

Carraro, L.; Bertuzzo, E.; Fronhofer, E. A.; Furrer, R.; Gounand, I.; Rinaldo, A.; Altermatt, F.

10.1101/2020.02.17.948851 — ecology — Posted on 2020-02-18

1583 Structure of dimeric full-length human ACE2 in complex with B0AT1

Zhou, Q.; Yan, R.; Zhang, Y.; Li, Y.; Xia, L.

10.1101/2020.02.17.951848 — biochemistry — Posted on 2020-02-18

1584 Long-read genome sequencing and assembly of Leptopilina boulardi: a specialist Drosophila parasitoid

Khan, S.; Sowpati, D. T.; Srinivasan, A.; Soujanya, M.; Mishra, R. K.

10.1101/2020.02.18.953885 — genomics — Posted on 2020-02-18

1585 AtCIPK16 Mediates Salt Stress Potentially Through Phytohormones and Transcription Factors

Amarasinghe, S. L.; Huang, W.; Watson-Haigh, N. S.; Gilliham, M.; Roy, S. J.; Baumann, U.

10.1101/2020.02.17.953216 — plant biology — Posted on 2020-02-18

1586 Hotspot KRAS mutations in brain metastases at the first metastatic recurrence of cutaneous melanoma

Rabbie, R.; Ferguson, P.; Wong, K.; Moran, U.; Turner, C.; Emanuel, P.; Haas, K.; Sanus, J. M.; Davidson, M. R.; Lakhani, S. R.; Shivalingam, B.; Long, G. V.; Parkinson, C.; Osman, I.; Scolyer, R. A.; Corrie, P.; Adams, D.

10.1101/2020.02.17.952630 — genomics — Posted on 2020-02-18

1587 Whole genome assembly of Culex tarsalis

Main, B. J.; Brown, C. T.; Marcantonio, M.; Barker, C. M.

10.1101/2020.02.17.951855 — genomics — Posted on 2020-02-18

1588 Agewise mapping of genomic oxidative DNA modification demonstrates oxidative-driven reprogramming of pro-longevity genes

Aung, L. H. H.; Wang, Y.; Liu, Z.-Q.; Li, Z.; Chen, X.; Yu, Z.; Shan, P.; Gao, J.; Li, P.

10.1101/2020.02.17.951582 — genetics — Posted on 2020-02-18

1589 Inhibitory neurons are a Central Controlling regulator in the effective cortical microconnectome.

Kajiwara, M.; Nomura, R.; Goetze, F.; Akutsu, T.; Shimono, M.

10.1101/2020.02.18.954016 — neuroscience — Posted on 2020-02-18

1590 Granulocyte-Colony Stimulating Factor reduces cocaine-seeking and downregulates glutamatergic synaptic proteins in medial prefrontal cortex

Hofford, R. S.; Euston, T. J.; Wilson, R. S.; Meckel, K. R.; Peck, E. G.; Godino, A.; Landry, J. A.; Calipari, E. S.; Lam, T. T.; Kiraly, D. D.

10.1101/2020.02.17.949990 — neuroscience — Posted on 2020-02-18

1591 Greater male than female variability in regional brain structure across the lifespan

Wierenga, L. M.; Doucet, G.; Dima, D.; Agartz, I.; Aghajani, M.; Akudjedu, T.; Albajes-Eizagirre, A.; Alnaes, D.; Alpert, K.; Andreassen, O. A.; Anticevic, A.; Asherson, P.; Banaschewski, T.; Bargallo, N.; Baumeister, S.; Baur-Streubel, R.; Bertolino, A.; Bonvino, A.; Boomsma, D.; Borgwardt, S.; Bourque, J.; den Braber, A.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R.; Busatto, G.; Calhoun, V.; Canales-Rodriguez, E.; Cannon, D.; Caseras, X.; Chaim-Avancini, T.; Ching, C.; Conrod, P.; Conzelmann, A.; Crivello, F.; Davey, C.; Dickie, E.; Ehrlich, S.; van 't Ent, D.; Fouche, J.-P.; Fuentes-

10.1101/2020.02.17.952010 — neuroscience — Posted on 2020-02-18

Farshad, M.; Pavlov, Y. G.; Kotchoubey, B. G.

10.1101/741728 — neuroscience — Posted on 2020-02-18

1593 Temporal and spatial dynamics of peat microbiomes in drained and rewetted soils of three temperate peatlands

Wang, H.; Weil, M.; Zak, D.; Muench, D.; Guenther, A.; Jurasinski, G.; Urich, T.

10.1101/2020.02.16.951285 — microbiology — Posted on 2020-02-18

1594 Renal tubule Cpt1a overexpression mitigates kidney fibrosis by restoring mitochondrial homeostasis

Miguel, V.; Tituana, J.; Herrero, J. I.; Herrero, L.; Serra, D.; Cuevas, P.; Barbas, C.; Rodriguez-Puyol, D.; Marquez-Exposito, L.; Ruiz-Ortega, M.; Castillo, C.; Sheng, X.; Susztak, K.; Ruiz-Canela, M.; Salas-Salvado, J.; Hu, F. B.; Martinez Gonzalez, M. A.; Ortega, S.; Ramos, R.; Lamas, S.

10.1101/2020.02.18.952440 — biochemistry — Posted on 2020-02-18

1595 Massively Parallel Analysis of Human 3' UTRs Reveals that AU-Rich Element Length and Registration Predict mRNA Destabilization

Siegel, D. A.; Le Tonqueze, O.; Biton, A.; Zaitlen, N.; Erle, D. J.

10.1101/2020.02.12.945063 — genomics — Posted on 2020-02-18

1596 S-Trap eliminates cell culture media polymeric surfactants for effective proteomic analysis of mammalian cell bioreactor supernatants

Zacchi, L. F.; Roche Recinos, D.; Otte, E.; Aitken, C.; Hunt, T.; Sandford, V.; Lee, Y. Y.; Schulz, B. L.; Howard, C. B.

10.1101/2020.02.17.951798 — biochemistry — Posted on 2020-02-18

1597 Distinct life histories impact dikaryotic genome evolution in the rust fungus Puccinia striiformis causing stripe rust in wheat

Schwessinger, B.; Chen, Y.-J.; Tien, R.; Vogt, J. K.; Sperschneider, J.; Nagar, R.; McMullan, M.; Sicheritz-Ponten, T.; Sorensen, C.; Hovmoller, M. S.; Rathjen, J.; Fejer Justesen, A.

10.1101/859728 — evolutionary biology — Posted on 2020-02-18

1598 Sphingolipids with Very Long-chain Fatty Acids Regulate Vacuole Fusion During Tethering and Docking

Hurst, L. R.; Zhang, C.; Kazmirchuk, T. D. D.; Rivera-Kohr, D. A.; Brett, C. L.; Fratti, R. A.

10.1101/2020.02.17.953331 — cell biology — Posted on 2020-02-18

George, E. A.; Pimplikar, S.; Thulasi, N.; Brockmann, A.

10.1101/2020.02.02.931345 — animal behavior and cognition — Posted on 2020-02-18

1600 G protein-Coupled Receptor Distribution Impacts the Effectiveness of Signal Transmission.

Chou, M.-Y.; Hu, Y.-Y.; Chuang, H.-h.

10.1101/2020.02.18.953554 — neuroscience — Posted on 2020-02-18

1601 Proteomic and phosphoproteomic analysis identifies novel liver-related signaling in retinal pigment epithelial cells during epithelial-mesenchymal transition

Mertz, J. L.; Sripathi, S. R.; Yang, X.; Chen, L.; Esumi, N.; Zhang, H.; Zack, D. J.

10.1101/2020.02.17.953315 — cell biology — Posted on 2020-02-18

1602 Mechanism of upstream promoter element stimulation of transcription at a ribosomal RNA promoter determined by single-molecule imaging

Mumm, J. P.; Friedman, L. J.; Gelles, J.

10.1101/2020.02.17.953182 — biochemistry — Posted on 2020-02-18

1603 A Domain-general Cognitive Core defined in Multimodally Parcellated Human Cortex

Assem, M.; Glasser, M. F.; Van Essen, D. C.; Duncan, J.

10.1101/517599 — neuroscience — Posted on 2020-02-18

1604 Functional relevance of dual olfactory bulb in olfactory coding

Kuruppath, P.; Bai, L.; Belluscio, L.

10.1101/588996 — neuroscience — Posted on 2020-02-18

1605 Observed but Never Experienced - Vicarious Learning of Fear Under Ecological Conditions

Szczepanik, M.; Kazmierowska, A. M.; Michałowski, J. M.; Wypych, M.; Olsson, A.; Knapska, E.

10.1101/2020.01.29.924720 — neuroscience — Posted on 2020-02-18

1606 Distinct natural syllable-selective neuronal ensembles in the primary auditory cortex of awake marmosets

Zeng, h.; Huang, J.-f.; Shen, Z.; Gong, N.; Wen, Y.-q.; Wang, L.; Poo, M.-m.

10.1101/2020.02.16.951194 — neuroscience — Posted on 2020-02-18

1607 Learning long temporal sequences in spiking networks by multiplexing neural oscillations

Vincent-Lamarre, P.; Calderini, M.; Thivierge, J.-P.

10.1101/766758 — neuroscience — Posted on 2020-02-18

1608 Signals of anticipation of reward and of mean reward rates in the human brain

Viviani, R.; Dommes, L.; Bosch, J. E.; Steffens, M.; Paul, A.; Schneider, K. L.; Stingl, J. C.; Beschoner, P.

10.1101/754663 — neuroscience — Posted on 2020-02-18

1609 Apical length governs computational diversity of L5 pyramidal neurons

Galloni, A. R.; Laffere, A.; Rancz, E. A.

10.1101/754499 — neuroscience — Posted on 2020-02-18

1610 Stimulus reliability automatically biases temporal integration of discrete perceptual targets

Rangelov, D.; West, R.; Mattingley, J. B.

10.1101/841353 — neuroscience — Posted on 2020-02-18

1611 Synaptic and supra-synaptic organisation of the dopaminergic projection to the striatum.

Pfeffer, M.; Pronot, M.; Angelo, M. F.; Walle, R.; Cordelieres, F. P.; Levet, F.; Claverol, S.; Lacome, S.; Petrel, M.; Martin, C.; Pitard, V.; Desmedt-Peyrusse, V.; Biederer, T.; Trifilieff, P.; Herzog, E.

10.1101/2020.02.18.952978 — neuroscience — Posted on 2020-02-18

1612 Distinct and sequential re-replication barriers ensure precise genome duplication

Zhou, Y.; Pozo, P. N.; Oh, S.; Stone, H. M.; Cook, J. G.

10.1101/366666 — molecular biology — Posted on 2020-02-18

1613 Highly expressed miR-375 is not an intracellular oncogene in Merkel cell polyomavirus-associated Merkel cell carcinoma

Fan, K.; Zebisch, A.; Horny, K.; Schrama, D.; Becker, J. C.

10.1101/813378 — cancer biology — Posted on 2020-02-18

1614 Real-time resolution of short-read assembly graph using ONT long reads

Nguyen, S.; Cao, M. D.; Coin, L. J. M.

10.1101/2020.02.17.953539 — bioinformatics — Posted on 2020-02-18

1615 Atomic Structure of the LL-37(17-29) Human Antimicrobial Peptide Reveals Functional Helical Fibril

Engelberg, Y.; Landau, M.

10.1101/2020.02.04.933432 — biochemistry — Posted on 2020-02-18

1616 Evolutionary relationships among Massospora spp. (Entomophthorales), obligate pathogens of cicadas

Macias, A. M.; Geiser, D. M.; Stajich, J. E.; Lukasik, P.; Veloso, C.; Bublitz, D. C.; Berger, M. C.; Boyce, G. R.; Hodge, K.; Kasson, M. T.

10.1101/811836 — microbiology — Posted on 2020-02-18

1617 MAnorm2 for quantitatively comparing groups of ChIP-seq samples

Tu, S.; Li, M.; Tan, F.; Chen, H.; Xu, J.; Waxman, D. J.; Zhang, Y.; Shao, Z.

10.1101/2020.01.07.896894 — bioinformatics — Posted on 2020-02-18

1618 XenoCP: Cloud-based BAM cleansing tool for RNA and DNA from Xenograft

Arunachalam, S.; Zhang, J.; Rusch, M.; Ding, L.; Thrasher, A.; Dyer, M.; Baker, S.; Jin, H.; Macias, M.; Kasper, L.

10.1101/843250 — bioinformatics — Posted on 2020-02-18

1619 Unstructured mRNAs form multivalent RNA-RNA interactions to generate TIS granule networks

Ma, W.; Zhen, G.; Xie, W.; Mayr, C.

10.1101/2020.02.14.949503 — molecular biology — Posted on 2020-02-18

1620 mTOR complex 1 and 2 regulate S6 kinase 1 activation in tandem.

Majeed, S. T.; Batool, A.; Majeed, R.; Bhat, N. N.; Andrabi, K. I.

10.1101/2020.02.15.944892 — cell biology — Posted on 2020-02-18

1621 Nuclear Plasticity Increases Susceptibility to Damage During Confined Migration

Mukherjee, A.; Barai, A.; Singh, R.; Yan, W.; Sen, S.

10.1101/2020.01.18.911529 — biophysics — Posted on 2020-02-18

1622 A Bayesian nonparametric approach to super-resolution single-molecule localization

Gabitto, M. I.; Marie-Nellie, H.; Pakman, A.; Pataki, A.; Darzacq, X.; Jordan, M.

10.1101/2020.02.15.950873 — bioinformatics — Posted on 2020-02-18

1623 In Silico identification of potential drug targets by subtractive genome analysis of Enterococcus faecium DO.

Karim, M.; Islam, M. N.; Jewel, G. M. N. A.

10.1101/2020.02.14.948232 — bioinformatics — Posted on 2020-02-18

1624 End-to-end assessment of fecal bacteriome analysis: from sample processing to DNA sequencing and bioinformatics results

Christoff, A. P.; Cruz, G. N. F.; Sereia, A. F. R.; Yamanaka, L. E.; Silveira, P. P.; de Oliveira, L. F. V.

10.1101/646349 — microbiology — Posted on 2020-02-18

1625 Development and application of eDNA-based tools for the conservation of white-clawed crayfish

Troth, C. R.; Burian, A.; Mauvisseau, Q.; Bulling, M.; Nightingale, J.; Mauvisseau, C.; Sweet, M. J.

10.1101/732941 — ecology — Posted on 2020-02-18

1626 A repository of web-based bioinformatics resources developed in India

Agarwal, A.; Agrawal, P.; Sharma, A.; Kumar, V.; Mugdal, C.; Dhall, A.; Raghava, G. P. S.

10.1101/2020.01.21.855627 — bioinformatics — Posted on 2020-02-18

1627 Prior Experience Alters the Appearance of Blurry Object Borders

Perez, D. C.; Cook, S. M.; Peterson, M. A.

10.1101/701995 — animal behavior and cognition — Posted on 2020-02-18

1628 Whole-genome sequencing of rare disease patients in a national healthcare system

Ouwehand, W. H.

10.1101/507244 — genomics — Posted on 2020-02-18

1629 Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model

Gibson, J. F.; Prajsnar, T. K.; Hill, C. J.; Tooke, A. K.; Serba, J. J.; Tonge, R. D.; Grierson, A. J.; Ingham, P. W.; Renshaw, S. A.; Johnston, S. A.

10.1101/604884 — immunology — Posted on 2020-02-18

1630 The tRNA pseudouridine synthase TruB1 regulates the maturation and function of let-7 miRNA

Kurimoto, R.; Chiba, T.; Ito, Y.; Matsushima, T.; Yano, Y.; Miyata, K.; Suzuki, T.; Tomita, K.; Asahara, H.

10.1101/2020.02.16.951954 — molecular biology — Posted on 2020-02-18

1631 Microfluidic platform for live cell imaging of 3D cultures with clone retrieval

Mulas, C.; Hodgson, A. C.; Kohler, T. N.; Agley, C. C.; Hollfelder, F.; Smith, A.; Chalut, K.

10.1101/2020.02.17.952689 — bioengineering — Posted on 2020-02-18

1632 Extraction of Protein Dynamics Information Hidden in Cryo-EM Map Using Deep Learning

Matsumoto, S.; Ishida, S.; Araki, M.; Kato, T.; Terayama, K.; Okuno, Y.

10.1101/2020.02.17.951863 — molecular biology — Posted on 2020-02-18

1633 Stony coral populations are more sensitive tochanges in vital rates in disturbed environments

Hall, T. E.; Freedman, A. S.; de Roos, A. M.; Edmunds, P. J.; Carpenter, R. C.; Gross, K.

10.1101/2020.02.17.952424 — ecology — Posted on 2020-02-18

1634 Comprehensive Network Analysis and Experimental Verification of Dedu Safflower's Influence on Ascites Hepatocarcinoma

Bao, L.; Wang, L.; Li, S.

10.1101/2020.02.17.952085 — cancer biology — Posted on 2020-02-18

1635 Double-stranded RNA bending by AU-tract sequences

Marin-Gonzalez, A.; Aicart-Ramos, C.; Marin-Baquero, M.; Martin-Gonzalez, A.; Suomalainen, M.; Kannan, A.; Vilhena, J. G.; Greber, U. F.; Moreno-Herrero, F.; Perez, R.

10.1101/2020.02.17.952044 — biophysics — Posted on 2020-02-17

1636 APA-Scan: Detection and Visualization of 3'-UTR APA with RNA-seq and 3'-end-seq Data

Fahmi, N. A.; Chang, J.-W.; Nassereddeen, H.; Ahmed, K. T.; Fan, D.; Yong, J.; Zhang, W.

10.1101/2020.02.16.951657 — bioinformatics — Posted on 2020-02-17

1637 Enhanced inhibitor tolerance and increased lipid productivity through adaptive laboratory evolution in the oleaginous yeast Metshnikowia pulcherrima

Hicks, R. H.; Sze, Y.; Chuck, C. J.; Henk, D. A.

10.1101/2020.02.17.952291 — bioengineering — Posted on 2020-02-17

1638 Random Forest Regression for Optimizing Variable Planting Rates for Corn and Soybean Using High-Resolution Topographical and Soil Data

Krause, M. R.; Crossman, S.; DuMond, T.; Lott, R.; Swede, J.; Arliss, S.; Robbins, R.; Ochs, D.; Gore, M. A.

10.1101/2020.02.17.952556 — plant biology — Posted on 2020-02-17

1639 A computational model explains and predicts substantia nigra pars reticulata responses to pallidal and striatal inputs

Phillips, R. S.; Rosner, I.; Gittis, A. H.; Rubin, J. E.

10.1101/2020.02.17.952820 — neuroscience — Posted on 2020-02-17

1640 A predictive processing model of episodic memory and time perception

Fountas, Z.; Sylaidi, A.; Nikiforou, K.; Seth, A.; Shanahan, M.; Roseboom, W.

10.1101/2020.02.17.953133 — neuroscience — Posted on 2020-02-17

1641 Semiautomated Detection Of Pseudomonas aeruginosa From Diverse Water Samples Using Highly Selective Z-Broth And Redoxpotential Monitor

Szita, G.; Szakmar, K.; Bernath, S.; Sövenyi, J.; Fülöp, G.; Hadjiev, J.; Csiko, G.; Solymosi, N.; Makrai, L.

10.1101/2020.02.17.946384 — microbiology — Posted on 2020-02-17

1642 Role of nanoscale antigen organization on B-cell activation probed using DNA origami

Veneziano, R.; Moyer, T.; Stone, M. B.; Shepherd, T. R.; Schief, W. R.; Irvine, D. J.; Bathe, M.

10.1101/2020.02.16.951475 — immunology — Posted on 2020-02-17

1643 Organoid Polymer Functionality and Mode of Klebsiella Pneumoniae Membrane Antigen Presentation Regulates Ex Vivo Germinal Center Epigenetics in Young and Aged B Cells

Graney, P. L.; Lai, K.; Post, S.; Brito, I.; Cyster, J.; Singh, A.

10.1101/2020.02.16.947408 — immunology — Posted on 2020-02-17

1644 A reference transcriptome for the early-branching fern Botrychium lunaria enables fine-grained resolution of population structure

Mossion, V.; Dauphin, B.; Grant, J.; Zemp, N.; Croll, D.

10.1101/2020.02.17.952283 — genomics — Posted on 2020-02-17

1645 High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KCNH2

Kozek, K. A.; Glazer, A. M.; Ng, C.-A.; Blackwell, D. J.; Egly, C. L.; Vanags, L. R.; Blair, M. A.; Mitchell, D. W.; Matreyek, K. A.; Fowler, D.; Knollmann, B. C.; Vandenberg, J. I.; Roden, D. M.; Kroncke, B. M.

10.1101/2020.02.17.952606 — genetics — Posted on 2020-02-17

1646 Accelerated cell cycles enable organ regeneration under developmental time constraints in the Drosophila hindgut

Cohen, E.; Fox, D. T.

10.1101/2020.02.17.953075 — developmental biology — Posted on 2020-02-17

1647 Branched chain amino acid aminotransferase 2 Regulates Ferroptotic Cell Death in Cancer Cells

Wang, K.; Zhang, Z.; Hsiang-i, T.; Liu, Y.; Wang, M.; Song, L.; Cao, X.; Xu, Z.; Chen, H.; Gong, A.; Wang, D.; Cheng, F.; Zhu, H.

10.1101/2020.02.17.952754 — cancer biology — Posted on 2020-02-17

1648 Nutritional stress alone can control in vitro tumor formation and its invasive nature

Gayan, S.; Teli, A.; Nair, A.; Dey, T.

10.1101/2020.02.17.952234 — cancer biology — Posted on 2020-02-17

1649 Contribution of CTCF binding to transcriptional activity at the HOXA locus in NPM1-mutant AML cells

Ghasemi, R.; Struthers, H.; Wilson, E. R.; Spencer, D. H.

10.1101/2020.02.17.952390 — genomics — Posted on 2020-02-17

1650 CRISPR-mediated isogenic cell-SELEX approach for generating highly specific aptamers against native membrane proteins

Rosch, J. C.; Neal, E. H.; Balikov, D. A.; Rahim, M.; Lippmann, E.

10.1101/2020.02.17.949768 — bioengineering — Posted on 2020-02-17

1651 Genome-scale conserved molecular principles of mRNA half-life regulation

Basu, S.; Mallik, S.; Hait, S.; Kundu, S.

10.1101/2020.02.17.952267 — systems biology — Posted on 2020-02-17

1652 Oncogenic mutant RAS activity is rescaled by the ERK/MAPK pathway

Gillies, T. E.; Pargett, M.; Silva, J. M.; Teragawa, C.; McCormick, F.; Albeck, J. G.

10.1101/2020.02.17.952093 — systems biology — Posted on 2020-02-17

1653 The Nucleosome Remodeling and Deacetylase complex has an asymmetric, dynamic, and modular architecture

Low, J. K.; Silva, A. P.; Sharifi Tabar, M.; Torrado, M.; Webb, S. R.; Parker, B. L.; Sana, M.; Smits, C.; Schmidberger, J. W.; Brillault, L.; Jackman, M. J.; Williams, D. C.; Blobel, G. A.; Hake, S. B.; Shepherd, N. E.; Landsberg, M. J.; Mackay, J. P.

10.1101/2020.02.17.951822 — biochemistry — Posted on 2020-02-17

1654 Behavioral features of motivated response to alcohol in Drosophila

Catalano, J. L.; Mei, N.; Azanchi, R.; Song, S. L.; Blackwater, T.; Heberlein, U.; Kaun, K. R.

10.1101/2020.02.17.953026 — animal behavior and cognition — Posted on 2020-02-17

1655 Rethinking success, integrity, and culture in research (Part 2) -- A multi-actor qualitative study on problems of science

Aubert Bonn, N.; Pinxten, W.

10.1101/2020.02.12.945899 — scientific communication and education — Posted on 2020-02-17

1656 Rethinking success, integrity, and culture in research (part 1) -- A multi-actor qualitative study on success in science

Aubert Bonn, N.; Pinxten, W.

10.1101/2020.02.12.945733 — scientific communication and education — Posted on 2020-02-17

1657 Identification of plant enhancers and their constituent elements by STARR-seq in tobacco leaves

Jores, T.; Dorrity, M. W.; Cuperus, J.; Fields, S.; Queitsch, C.

10.1101/2020.02.17.952747 — plant biology — Posted on 2020-02-17

1658 Influence of normobaric hypoxic exercise on endothelial progenitor cell senescence by in vitro cultivation with conditioned media

Harmsen, J.-F.; Nebe, D.; Brixius, K.; Schenk, A.; Bloch, W.

10.1101/2020.02.16.949677 — physiology — Posted on 2020-02-17

1659 Renoprotective and haemodynamic effects of adiponectin and peroxisome proliferator-activated receptor agonist, pioglitazone, in renal vasculature of diabetic Spontaneously hypertensive rats

Afzal, S.; Abdul Sattar, M. Z.; Eseyin, O.; Johns, E. J.

10.1101/2020.02.17.952507 — pharmacology and toxicology — Posted on 2020-02-17

1660 KD-64 - a new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist - caffeine does not reduce diet-induced obesity in mice

Kotanska, M.; Dziubina, A.; Szafarz, M.; Mika, K.; Reguła, K.; Bednarski, M.; Zygmunt, M.; Drabczynska, A.; Sapa, J.; Kiec-Kononowicz, K.

10.1101/2020.02.17.952531 — pharmacology and toxicology — Posted on 2020-02-17

1661 Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: UK Biobank 18608 example

Maximov, I.; van der Meer, D.; de Lange, A.-M.; Kaufmann, T.; Shadrin, A.; Frei, O.; Wolfers, T.; Westlye, L. T.

10.1101/2020.02.17.952697 — neuroscience — Posted on 2020-02-17

1662 Systematic quantification of synapses in primary neuronal culture

Verstraelen, P.; Garcia-Diaz Barriga, G.; Verschuuren, M.; Asselbergh, B.; Nuydens, R.; Larsen, P.; Timmermans, J.-P.; De Vos, W. H.

10.1101/2020.02.17.952242 — neuroscience — Posted on 2020-02-17

1663 Vps54 regulates Drosophila neuromuscular junction development and controls postsynaptic density composition via a Rab7-dependent mechanism

Patel, P. H.; Wilkinson, E. C.; Starke, E. L.; McGimsey, M. R.; Blankenship, J. T.; Barbee, S. A.

10.1101/2020.02.17.952721 — neuroscience — Posted on 2020-02-17

1664 Robust range of auditory periphery development, eye opening, and brain gene expression in Wistar rat pups that experience variation in maternal backgrounds

Rodriguez-Contreras, A.; Cardoso, L.; Liu, J.; Champagne, F. A.; de Paolis, A.; Pan, G.; Singh, P.; Qiu, J.

10.1101/2020.02.17.953117 — neuroscience — Posted on 2020-02-17

1665 Anode surface bioaugmentation enhances deterministic biofilm assembly in microbial fuel cells

Yanuka-Golub, K.; Dubinsky, V.; Korenblum, E.; Reshef, L.; Ofek-Lalzar, M.; Rishpon, J.; Gophna, U.

10.1101/2020.02.17.951574 — microbiology — Posted on 2020-02-17

1666 Temperature modulates stress response in anammox reactors

Niederdorfer, R.; Hausherr, D.; Palomo, A.; Wei, J.; Magyar, P.; Smets, B. F.; Joss, A.; Buergmann, H.

10.1101/2020.02.17.952358 — microbiology — Posted on 2020-02-17

1667 The Structures of Secretory and Dimeric Immunoglobulin A

Kumar Bharathkar, S.; Parker, B. W.; Malyutin, A.; Haloi, N.; Tajkhorshid, E.; Stadtmueller, B.

10.1101/2020.02.16.951780 — immunology — Posted on 2020-02-17

1668 Vaccinia virus infection inhibits skin dendritic cell migration to draining lymph node

Aggio, J. B.; Krmeska, V.; Ferguson, B. J.; Wowk, P. F.; Rothfuchs, A. G.

10.1101/2020.02.17.952374 — immunology — Posted on 2020-02-17

1669 Effect of structural stability on endolysosomal degradation and T-cell reactivity of major shrimp allergen tropomyosin

Kamath, S. D.; Scheiblhofer, S.; Johnson, C. M.; Machado, Y.; McClean, T.; Taki, A.; Ramsland, P.; Iyer, S.; Hofer, H.; Wallner, M.; Joubert, I.; Rolland, J.; O'Hehir, R.; Briza, P.; Ferreira, F.; Weiss, R.; Lopata, A. L.

10.1101/2020.02.17.919845 — immunology — Posted on 2020-02-17

1670 CellOracle: Dissecting cell identity via network inference and in silico gene perturbation

Kamimoto, K.; Hoffmann, C. M.; Morris, S. A.

10.1101/2020.02.17.947416 — genomics — Posted on 2020-02-17

1671 Phylogeny and distribution of Y-chromosomal haplotypes in domestic, ancient and wild goats

Nijman, I. J.; Rosen, B. D.; Zheng, Z.; Jiang, Y.; Cumer, T.; Daly, K. G.; Balteanu, V. B.; Berger, B.; Blichfeldt, T.; Boink, G.; Carolan, S.; Cubric-Curik, V.; Kantanen, J.; Martinez, A.; Mazza, R.; Khayatzadeh, N.; Kim, N.; Ouchene-Khelifi, N.-A.; Pereira, F.; da Silva, A.; Simcic, M.; Soelkner, J.; Sutherland, A.; Tigchelaar, J.; Ajmone-Marsan, P.; Bradley, D. G.; Pompanon, F.; Colli, L.; Lenstra, J. A.

10.1101/2020.02.17.952051 — genetics — Posted on 2020-02-17

1672 Trans-generational effect of protein restricted diet on adult body and wing size of Drosophila melanogaster

Yadav, P.; Krittika, S.

10.1101/2020.02.17.952101 — evolutionary biology — Posted on 2020-02-17

1673 Coral reef restoration efforts in Latin American countries and territories

Bayraktarov, E.; Banaszak, A.; Montoya Maya, P. H.; Kleypas, J.; Arias-Gonzalez, J. E.; Blanco, M.; Calle, J.; Charuvi, N.; Cortes Useche, C.; Galvan, V. M.; Garcia Salgado, M. A.; Gnecco, M.; Guendulain Garcia, S. D.; Hernandez Delgado, E. A.; Marin Moraga, J. A.; Maya, M. F.; Mendoza Quiroz, S.; Mercado Cervantes, S.; Morikawa, M.; Nava, G.; Pizarro, V.; Sellares-Blasco, R. I.; Suleiman Ramos, S. E.; Villalobos Cubero, T.; Villalpando, M.; Frias-Torres, S.

10.1101/2020.02.16.950998 — ecology — Posted on 2020-02-17

1674 Whole exome precision oncology targeting synthetic lethal vulnerabilities across the tumor transcriptome

Lee, J. S.; Nair, N. U.; Chapman, L. M.; Sinha, S.; Wang, K.; Cha, H.; Rubin, E.; Berger, R.; Lazar, V.; Kurzrock, R.; Gilbert, M. R.; Hannenhalli, S. S.; Lee, S.-H.; Aldape, K.; Ruppin, E.

10.1101/2020.02.16.951699 — cancer biology — Posted on 2020-02-17

1675 Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

Tsai, P.-Y.; Lee, M.-S.; Jadhav, U.; Naqvi, I.; Madha, S.; Adler, A.; Mistry, M.; Lewis, C. A.; Hitchcock, D. S.; Roberts, F. R.; DelNero, P.; Hank, T.; Honselmann, K. C.; Morales Oyarvide, V.; Mino-Kenudson, M.; Clish, C. B.; Shivdasani, R. A.; Kalaany, N. Y.

10.1101/2020.02.16.951681 — cancer biology — Posted on 2020-02-17

1676 APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers that are associated with early-onset and dismal prognosis

Fennell, L.; Kane, A.; Liu, C.; Mckeone, D.; Fernando, W.; Bond, C.; Jamieson, S.; Dumenil, T.; Patch, A.-M.; Kazakoff, S.; Pearson, J.; Waddell, N.; Leggett, B.; Whitehall, V.

10.1101/2020.02.16.942904 — cancer biology — Posted on 2020-02-17

1677 Assessing predictors for new post translational modification sites: a case study on hydroxylation

Piovesan, D.; Hatos, A.; Minervini, G.; Quaglia, F.; Monzon, A. M.; Tosatto, S. C. E.

10.1101/2020.02.17.952127 — bioinformatics — Posted on 2020-02-17

1678 BARTweb: a web server for transcription factor association analysis

Ma, W.; Wang, Z.; Zhang, Y.; Magee, N. E.; Chen, Y.; Zang, C.

10.1101/2020.02.17.952838 — bioinformatics — Posted on 2020-02-17

1679 Experimentally determined long intrinsically disordered protein regions are now abundant in the Protein Data Bank

Monzon, A. M.; Necci, M.; Quaglia, F.; Walsh, I.; Piovesan, D.; Zanotti, G.; Tosatto, S. C. E.

10.1101/2020.02.17.952028 — bioinformatics — Posted on 2020-02-17

1680 Adaptive Baseline Fitting for 1H MR Spectroscopy Analysis

Wilson, M.

10.1101/2020.02.17.949495 — biochemistry — Posted on 2020-02-17

1681 Recalling a single object: going beyond the capacity debate

Sengupta, R.; Lewis, C. M.; Bapi, R. S.

10.1101/2020.02.17.951921 — animal behavior and cognition — Posted on 2020-02-17

1682 SAMHD1 limits the efficacy of forodesine in leukaemia by protecting cells against cytotoxicity of dGTP

Davenne, T.; Klintman, J.; Sharma, S.; Rigby, R. E.; Cursi, C.; Bridgeman, A.; Dadonaite, B.; De Keersmaecker, K.; Hillmen, P.; Chabes, A.; Schuh, A.; Rehwinkel, J.

10.1101/2020.02.17.951517 — cancer biology — Posted on 2020-02-17

1683 Oocytes, a single cell and a tissue

Wu, D.; Dean, J.

10.1101/2020.02.17.952929 — bioinformatics — Posted on 2020-02-17

1684 Transcriptome analysis reveals the effects of transgenic expression of the Gal4 protein on normal gene expression in silkworm tissues

Chen, T.; Ma, Y.; Liu, R.; Tan, T.; Huang, L.; Xu, H.

10.1101/2020.02.17.952523 — genomics — Posted on 2020-02-17

1685 IRE1? regulates macrophage polarization, PD-L1 expression and tumor survival

Zanetti, M.; Batista, A. T.; Rodvold, J.; Xian, S.; Searles, S. T.; Lew, A.; Iwawaki, T.; Almanza, G.; Weller, T. C.; Lin, J.; Jepsen, K.; Carter, H.

10.1101/2020.02.17.952457 — cancer biology — Posted on 2020-02-17

1686 The separation of Antler Polypeptide and its effects on the proliferation and osteogenetic differentiation of Bone Marrow Mesenchymal Stem Cells

Wang, P.; Sun, T.-f.; Li, G.; Zhang, H.-m.; Liu, F.-j.; Gao, Z.-h.; Cao, S.-n.; Sun, G.-d.; Du, H.-t.; Wang, C.-a.; Wang, D.; Shi, B.; Lin, L.

10.1101/2020.02.17.952499 — biochemistry — Posted on 2020-02-17

1687 Generation of multi-transgenic pigs using PiggyBac transposons co-expressing pectinase, xylanase, cellulase?β-1.3-1.4-glucanase and phytase

Wang, H.; Li, G.; Zhong, C.; Mo, J.; Sun, Y.; Shi, J.; Zhou, R.; Li, Z.; Yang, H.; Wu, Z.; Liu, D.; Zhang, X.

10.1101/2020.02.17.952515 — genetics — Posted on 2020-02-17

1688 Common postzygotic mutational signature in multiple healthy adult tissues related to embryonic hypoxia

Hong, Y.; Zhang, D.; Zhou, X.; Chen, A.; Abliz, A.; Bai, J.; Wang, L.; Hu, Q.; Gong, K.; Guan, X.; Liu, M.; Zheng, X.; Lai, S.; Qu, H.; Zhao, F.; Hao, S.; Wu, Z.; Cai, H.; Hu, S.; Ma, Y.; Zhang, J.; Ke, Y.; Wang, Q.; Chen, W.; Zeng, C.

10.1101/2020.02.17.952473 — genetics — Posted on 2020-02-17

1689 Microhabitat and ectomycorrhizal effects on the establishment, growth and survival of Quercus ilex L. seedlings under drought

Garcia de Jalon, L.; Limousin, J.-M.; Richard, F.; Gessler, A.; Peter, M.; Hattenschwiler, S.; Milcu, A.

10.1101/2020.02.17.952549 — ecology — Posted on 2020-02-17

1690 TGF-β inhibitor accelerates BMP4-induced cochlear gap junction formation during in vitro differentiation of embryonic stem cells

Fukunaga, I.; Chen, C.; Oe, Y.; Danzaki, K.; Ohta, S.; Koike, A.; Fujimoto, A.; Ikeda, K.; Kamiya, K.

10.1101/2020.02.17.952481 — cell biology — Posted on 2020-02-17

1691 AncesTree: an interactive immunoglobulin lineage tree visualizer

Foglierini, M.; Pappas, L.; Lanzavecchia, A.; Corti, D.; Perez, L.

10.1101/2020.02.17.952465 — bioinformatics — Posted on 2020-02-17

1692 Endosidin20 targets cellulose synthase catalytic domain to inhibit cellulose biosynthesis

Huang, L.; Li, X.; Zhang, W.; Ung, N.; Liu, N.; Yin, X.; Li, Y.; Mcewan, R. E.; Dilkes, B. P.; Dai, M.; Hicks, G. R.; Raikhel, N. V.; Staiger, C. J.; Zhang, C.

10.1101/2020.02.16.946244 — plant biology — Posted on 2020-02-17

1693 Direct nanopore sequencing of mRNA reveals landscape of transcript isoforms in apicomplexan parasites

Lee, V. V.; Judd, L.; Jex, A.; Holt, K. E.; Tonkin, C.; Ralph, S.

10.1101/2020.02.16.946699 — genomics — Posted on 2020-02-17

1694 Capybara: A computational tool to measure cell identity and fate transitions

Kong, W.; Fu, Y. C.; Morris, S. A.

10.1101/2020.02.17.947390 — genomics — Posted on 2020-02-17

1695 Regulatory architecture of the RCA gene cluster captures an intragenic TAD boundary and enhancer elements in B cells

Cheng, J.; Clayton, J. S.; Acemel, R. D.; Gomez-Skarmeta, J. L.; Taylor, R. L.; Harley, J. B.; Quail, E.; Ulgiati, D.

10.1101/2020.02.16.941070 — genetics — Posted on 2020-02-17

1696 Greater male than female variability in regional brain structure across the lifespan

10.1101/2020.02.17.952010 — neuroscience — Posted on 2020-02-17

1697 Induction Of Chronic Stress Reveals An Interplay Of Stress Granules And TDP-43 Pathological Aggregates In Human ALS Fibroblasts And iPSC-Neurons

Ratti, A.; Gumina, V.; Lenzi, P.; Bossolasco, P.; Fulceri, F.; Volpe, C.; Bardelli, D.; Pregnolato, F.; Maraschi, A.; Fornai, F.; Silani, V.; Colombrita, C.

10.1101/2020.02.17.951434 — neuroscience — Posted on 2020-02-17

1698 Identification of multiple noise sources improves estimation of neural responses across stimulus conditions

Weber, A. I.; Shea-Brown, E.; Rieke, F.

10.1101/2020.02.17.951830 — neuroscience — Posted on 2020-02-17

1699 Aberrant astrocyte protein secretion contributes to altered neuronal development in diverse disorders

Caldwell, A. L.; Diedrich, J. K.; Shokhirev, M. N.; Allen, N. J.

10.1101/2020.02.17.939991 — neuroscience — Posted on 2020-02-17

1700 Ceftriaxone and mGlu2/3 interactions in the nucleus accumbens core affect the reinstatement of cocaine-seeking in male and female rats

Logan, C. N.; Bechard, A. R.; Hamor, P. U.; Wu, L.; Schwendt, M.; Knackstedt, L. A.

10.1101/2020.02.17.952762 — neuroscience — Posted on 2020-02-17

1701 Cell substrate patterns driven by curvature-sensitive actin polymerization: waves and podosomes.

Naoz, M.; Gov, N.

10.1101/2020.02.17.953018 — biophysics — Posted on 2020-02-17

1702 Single-molecule fluorescence-based approach reveals novel mechanistic insights into small heat shock protein chaperone function

Johnston, C. L.; Marzano, N. R.; Paudel, B.; Wright, G.; Benesch, J. L. P.; van Oijen, A. M.; Ecroyd, H.

10.1101/2020.02.16.951632 — biochemistry — Posted on 2020-02-17

1703 Subcellular localization and mitotic interactome analyses identify SIRT4 as a centrosomally localized and microtubule associated protein

Bergmann, L.; Lang, A.; Bross, C.; Altinoluk-Hambuechen, S.; Fey, I.; Overbeck, N.; Stefanski, A.; Wiek, C.; Verhuelsdonk, P.; Mielke, C.; Sohn, D.; Stühler, K.; Hanenberg, H.; Jänicke, R. U.; Scheller, J.; Reichert, A. S.; Ahmadian, M. R.; Piekorz, R. P.

10.1101/2020.02.17.940692 — cell biology — Posted on 2020-02-17

1704 Overcoming efflux of fluorescent probes for actin imaging in living cells

Gerasimaite, R.; Seikowski, J.; Schimpfhauser, J.; Kostiuk, G.; Gilat, T.; D'Este, E.; Schnorrenberg, S.; Lukinavicius, G.

10.1101/2020.02.17.951525 — biochemistry — Posted on 2020-02-17

1705 High antibody titres induced by protein subunit vaccines against Buruli ulcer using Mycobacterium ulcerans antigens Hsp18 and MUL_3720

Mangas, K. M.; Tobias, N. J.; Marion, E.; Babonneau, J.; Marsollier, L.; Porter, J. L.; Pidot, S. J.; Wong, C. Y.; Jackson, D. C.; Chua, B. Y.; Stinear, T. P.

10.1101/2020.02.16.951533 — microbiology — Posted on 2020-02-17

1706 Hnf4a-mediated regulation of proximal tubule progenitors in the mouse kidney

Marable, S. S.; Chung, E.; Park, J.-S.

10.1101/2020.02.16.951731 — developmental biology — Posted on 2020-02-17

1707 High-temperature live-cell imaging of cytokinesis, cell motility and cell-cell adhesion in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius

Charles-Orszag, A.; Lord, S. J.; Mullins, D.

10.1101/2020.02.16.951772 — cell biology — Posted on 2020-02-17

1708 Accelerating Monte Carlo modeling of structured-light based diffuse optical imaging via "photon sharing"

Yan, S.; Yao, R.; Intes, X.; Fang, Q.

10.1101/2020.02.16.951590 — biophysics — Posted on 2020-02-17

1709 Functional principal component based time-series genome-wide association in sorghum

Miao, C.; Xu, Y.; Liu, S.; Schnable, P. S.; Schnable, J. C.

10.1101/2020.02.16.951467 — plant biology — Posted on 2020-02-17

1710 MouseCircuits.org: An online repository to guide the circuit era of disordered affect

Anderson, K. R.; Dumitriu, D.

10.1101/2020.02.16.951608 — neuroscience — Posted on 2020-02-17

1711 Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube

Symonds, A.; Buckley, C.; Williams, C.; Clarke, J.

10.1101/2020.02.16.950543 — neuroscience — Posted on 2020-02-17

1712 Core Role of TRPC6 Channels in Regulating Airway Re-modelling in Chronic Obstructive Pulmonary Disease.

Fei, Z.; Hao, Q.

10.1101/2020.01.16.908699 — cell biology — Posted on 2020-02-17

1713 Buckling of epithelium growing under spherical confinement

Trushko, A.; Di Meglio, I.; Merzouki, A.; Blanch-Mercader, C.; Abuhattum, S.; Guck, J.; Alessandri, K.; Nassoy, P.; Kruse, K.; Chopard, B.; Roux, A.

10.1101/513119 — biophysics — Posted on 2020-02-17

1714 The nonlinear structure of linkage disequilibrium

Smith, R. D.

10.1101/566208 — genetics — Posted on 2020-02-17

1715 Headwaters fed by subterranean ice: potential climate refugia for mountain stream communities?

Tronstad, L. M.; Hotaling, S.; Giersch, J. J.; Wilmot, O. J.; Finn, D. S.

10.1101/788273 — ecology — Posted on 2020-02-17

1716 Toxoplasma GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

Mukhopadhyay, D.; Arranz-Solis, D.; Saeij, J. P.

10.1101/2020.02.14.950360 — immunology — Posted on 2020-02-17

1717 The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling

Athukoralage, J. S.; Grüschow, S.; Graham, S.; Czekster, C. M.; Rouillon, C.; White, M. F.

10.1101/2020.02.12.946046 — biochemistry — Posted on 2020-02-17

1718 Modeling the post-translational modifications and its effects in the NF-κB pathway

Ramachandran, S.; Mobeen, A.

10.1101/2020.02.13.947010 — systems biology — Posted on 2020-02-17

1719 Branched-chain amino acid catabolism depends on GRXS15 through mitochondrial lipoyl cofactor homeostasis

Moseler, A.; Kruse, I.; Maclean, A. E.; Pedroletti, L.; Wagner, S.; Wehler, R.; Fischer-Schrader, K.; Poschet, G.; Wirtz, M.; Dörmann, P.; Hildebrandt, T. M.; Hell, R.; Schwarzländer, M.; Balk, J.; Meyer, A. J.

10.1101/2020.02.13.947697 — plant biology — Posted on 2020-02-17

1720 Reduced levels of membrane-bound alkaline phosphatase in Vip3Aa-resistant Heliothis virescens

Pinos, D.; Chakroun, M.; Millan-Leiva, A.; Jurat-Fuentes, J. L.; Wright, D.; Hernandez-Martinez, P.; Ferre, J.

10.1101/2020.02.10.943167 — microbiology — Posted on 2020-02-17

1721 A NKp80-based identification strategy reveals that CD56neg NK cells are not completely dysfunctional in health and disease.

Orrantia, A.; Terren, I.; Izquierdo-Lafuente, A.; Alonso-Cabrera, J. A.; Sanda, V.; Vitalle, J.; Moreno, S.; Tasias, M.; Uranga, A.; Gonzalez, C.; Mateos, J. J.; Garcia-Ruiz, J. C.; Zenarruzabeitia, O.; Borrego, F.

10.1101/2020.02.12.945105 — immunology — Posted on 2020-02-17

1722 Formicine ants swallow their highly acidic poison for gut microbial selection and control

Tragust, S.; Herrmann, C.; Häfner, J.; Braasch, R.; Tilgen, C.; Hoock, M.; Milidakis, M. A.; Gross, R.; Feldhaar, H.

10.1101/2020.02.13.947432 — evolutionary biology — Posted on 2020-02-17

1723 Ancestral duplicated DL/CRC orthologs display function on orchid reproductive organ innovation

Chen, Y.-Y.; Hsiao, Y.-Y.; Li, C.-I.; Yeh, C.-M.; Mitsuda, N.; Yang, H.; Chiu, C.-C.; Chang, S.-B.; Liu, Z.-J.; Tsai, W.-C.

10.1101/2020.02.12.945865 — developmental biology — Posted on 2020-02-17

1724 Non-negative least squares computation for in vivo myelin mapping using simulated multi-echo spin-echo T2 decay data

Wiggermann, V.; Vavasour, I. M.; Kolind, S.; MacKay, A. L.; Helms, G.; Rauscher, A.

10.1101/2020.02.15.948976 — biophysics — Posted on 2020-02-17

1725 Long-term implicit memory for sequential auditory patterns in humans

Bianco, R.; Harrison, P. M. C.; Hu, M.; Bolger, C.; Picken, S.; Pearce, M. T.; Chait, M.

10.1101/2020.02.14.949404 — neuroscience — Posted on 2020-02-17

1726 Why not record from every electrode with a CMOS scanning probe?

Dimitriadis, G.; Neto, J. P.; Aarts, A.; Alexandru, A.; Ballini, M.; Battaglia, F.; Calcaterra, L.; Chen, S.; David, F.; Fiath, R.; Frazao, J.; Geerts, J. P.; Gentet, L. J.; Helleputte, N. V.; Holzhammer, T.; Hoof, C. v.; Horvath, D.; Lopes, G.; Lopez, C. M.; Maris, E.; Marques-Smith, A.; Marton, G.; McNaughton, B. L.; Meszena, D.; Mitra, S.; Musa, S.; Neves, H.; Nogueira, J.; Orban, G. A.; Pothof, F.; Putzeys, J.; Raducanu, B.; Ruther, P.; Schroeder, T.; Singer, W.; Steinmetz, N. A.; Tiesinga, P.; Ulbert, I.; Wang, S.; Welkenhuysen, M.; Kampff, A. R.

10.1101/275818 — neuroscience — Posted on 2020-02-17

1727 Prompt rewetting of drained peatlands reduces climate warming despite methane emissions

Günther, A.; Barthelmes, A.; Huth, V.; Joosten, H.; Jurasinski, G.; Koebsch, F.; Couwenberg, J.

10.1101/748830 — ecology — Posted on 2020-02-17

1728 A psychometric evaluation of the 12-item EPQ-R neuroticism scale in 502,591 UK Biobank participants using item response theory (IRT)

Bauermeister, S.; Gallacher, J. E. J.

10.1101/741249 — neuroscience — Posted on 2020-02-17

1729 Autophagy promotes cell and organismal survival by maintaining NAD(H) pools

Sedlackova, L.; Otten, E. G.; Scialo, F.; Shapira, D.; Kataura, T.; Carroll, B.; Seranova, E.; Rabanal Ruiz, Y.; Kelly, G.; Stefanatos, R.; Nelson, G.; Urselli, F.; Acharjee, A.; Kenneth, N. S.; Trushin, S. A.; Bascom, C.; Tasseff, R.; Isfort, R. I.; Oblong, J.; Trushina, E.; Imoto, M.; Saiki, S.; Lazarou, M.; Papamichos Chronakis, M.; Maddocks, O. D. K.; Sarkar, S.; Sanz, A.; Korolchuk, V. I.

10.1101/2020.01.31.928424 — cell biology — Posted on 2020-02-17

1730 Class III peroxidases PRX01, PRX44, and PRX73 potentially target extensins during root hair growth in Arabidopsis thaliana

Marzol, E.; Borassi, C.; Estevez, J. M.

10.1101/2020.02.04.932376 — plant biology — Posted on 2020-02-17

1731 Separability and Geometry of Object Manifolds in Deep Neural Networks

Cohen, U.; Chung, S.; Lee, D. D.; Sompolinsky, H.

10.1101/644658 — neuroscience — Posted on 2020-02-17

1732 Dopamine manipulations modulate paranoid social inferences in healthy people.

Barnby, J. M.; Bell, V.; Deeley, Q.; Mehta, M. A.

10.1101/2019.12.18.874255 — neuroscience — Posted on 2020-02-17

1733 Helicobacter small RNA regulates host adaptation and carcinogenesis

10.1101/2020.02.15.950279 — microbiology — Posted on 2020-02-17

1734 Bifurcation analysis of an impulsive system describing a Partial Nitritation and Anammox in a hybrid reactor

Wade, M. J.; Wolkowicz, G. S. K.

10.1101/2020.02.14.949099 — bioengineering — Posted on 2020-02-17

1735 Rewetting of three drained peatlands drives congruent compositional changes in pro- and eukaryotic soil microbiomes through environmental filtering

Weil, M.; Wang, H.; Bengtsson, M. M.; Koehn, D.; Guenther, A.; Jurasinski, G.; Negassa, W.; Couwenberg, J.; Zak, D.; Urich, T.

10.1101/848192 — microbiology — Posted on 2020-02-17

1736 AS-Quant: Detection and Visualization of Alternative Splicing Events with RNA-seq Data

Fahmi, N. A.; Yeh, H.-S.; Chang, J.-W.; Nassereddeen, H.; Fan, D.; Yong, J.; Zhang, W.

10.1101/2020.02.15.950287 — bioinformatics — Posted on 2020-02-17

1737 CNN explains tuning properties of anterior, but not middle, face-processing areas in macaque IT

Raman, R.; Hosoya, H.

10.1101/686121 — neuroscience — Posted on 2020-02-17

1738 Heart Rate n-Variability (HRnV) and Its Application to Risk Stratification of Chest Pain Patients in the Emergency Department

Liu, N.; Guo, D.; Koh, Z. X.; Ho, A.; Xie, F.; Tagami, T.; Sakamoto, J.; Pek, P. P.; Chakraborty, B.; Lim, S. H.; Tan, J.; Ong, M.

10.1101/738989 — bioengineering — Posted on 2020-02-17

1739 A Test of Memory: The Fish, The Mouse, The Fly And The Human

Cleal, M.; Fontana, B. D.; Ranson, D. C.; McBride, S. D.; Swinny, J. D.; Redhead, E. S.; Parker, M. O.

10.1101/2020.02.15.950816 — animal behavior and cognition — Posted on 2020-02-16

1740 Proteogenomic heterogeneity of localized human prostate cancer progression

Charmpi, K.; Guo, T.; Zhong, Q.; Wagner, U.; Sun, R.; Toussaint, N. C.; Fritz, C.; Yuan, C.; Chen, H.; Rupp, N. J.; Christiansen, A.; Rutishauser, D.; Ruschoff, J. H.; Fankhauser, C.; Saba, K.; Poyet, C.; Hermanns, T.; Oehl, K.; Moore, A. L.; Beisel, C.; Calzone, L.; MARTIGNETTI, L.; Zhang, Q.; Zhu, Y. J.; Martinez, M. R.; Manica, M.; Haffner, M. C.; Aebersold, R.; Wild, P. J.; Beyer, A.

10.1101/2020.02.16.950378 — systems biology — Posted on 2020-02-16

1741 Rapid quantitative imaging of high intensity ultrasonic pressure fields

Luo, H.; Kusunose, J.; Pinton, G.; Caskey, C. F.; Grissom, W. A.

10.1101/2020.02.15.951046 — bioengineering — Posted on 2020-02-16

1742 A Single Nucleotide Polymorphism assay sheds light on the extent and distribution of genetic diversity, population structure and functional basis of key traits in cultivated North American Cannabis

Henry, P.; Khatodia, S.; Kapoor, K.; Gonzales, B.; Middleton, A.; Hong, K.; Hilyard, A.; Johnson, S.; Allen, D.; Chester, Z.; Jin, D.; Jule, J. C. R.; Wilso, I.; Gangola, M.; Broome, E. J.; Caplan, D.; Adhikary, D.; Deyholos, M.; Morgan, M.; Hall, O.; Guppy, B.; Orser, C.

10.1101/2020.02.16.951459 — plant biology — Posted on 2020-02-16

1743 Immunoinformatic design of multi epitopes peptide-based universal cancer vaccine using matrix metalloproteinase-9 protein as a target

abdelmoneim, a. h.; Mustafa, M. I.; Abdelmageed, M. I.; Murshed, N. S.; Dawoud, E. d.; Ahmed, E. M.; Kamal eldein, R. M.; Elfadol, N. M.; Mohamed sati, A. O.; Makhawi, A. M.

10.1101/2020.02.16.951319 — immunology — Posted on 2020-02-16

1744 Protein solubility is controlled by global structural flexibility

Bhandari, B. K.; Gardner, P. P.; Lim, C. S.

10.1101/2020.02.15.951012 — bioinformatics — Posted on 2020-02-16

1745 Global multi-environment resistance QTL for foliar late blight resistance in tetraploid potato with tropical adaptation

Lindqvist-Kreuze, H.; de Boeck, B.; Unger, P.; Gemenet, D. C.; Li, X.; Pan, Z.; Sui, Q.; Qin, J.; Woldegjorgis, G.; Negash, K.; Hussen, I.; Hirut, B.; Gastelo, M.; De Vega, J. J.; Bonierbale, M.

10.1101/2020.02.16.950618 — genomics — Posted on 2020-02-16

1746 A novel two-indenter based micro-pump for lab-on-a-chip application: modeling and characterizing flows for a non-Newtonian fluid

Avvari, R. K.

10.1101/2020.02.15.951111 — bioengineering — Posted on 2020-02-16

1747 Cross-Protection Against Zika Virus Infection Conferred by a Live Attenuated Japanese Encephalitis SA14-14-2 Vaccine

Wang, R.; Zhen, Z.; Turtle, L.; Hou, B.; Li, Y.; Gao, N.; Fan, D.; Chen, H.; An, J.

10.1101/2020.02.14.950352 — microbiology — Posted on 2020-02-16

1748 Temporal and spatial dynamics of peat microbiomes in drained and rewetted soils of three temperate peatlands

Wang, H.; Weil, M.; Zak, D.; Muench, D.; Guenther, A.; Jurasinski, G.; Urich, T.

10.1101/2020.02.16.951285 — microbiology — Posted on 2020-02-16

1749 High-throughput mapping of the phage resistance landscape in E. coli

Mutalik, V. K.; Adler, B. A.; Rishi, H. S.; Piya, D.; Zhong, C.; Koskella, B.; Calendar, R.; Novichkov, P.; Price, M. N.; Deutschbauer, A. M.; Arkin, A. P.

10.1101/2020.02.15.951020 — microbiology — Posted on 2020-02-16

1750 The environmental impacts of palm oil and its alternatives

Beyer, R. M.; Duran, A. P.; Rademacher, T. T.; Martin, P.; Tayleur, C.; Brooks, S. E.; Coomes, D.; Donald, P. F.; Sanderson, F. J.

10.1101/2020.02.16.951301 — ecology — Posted on 2020-02-16

1751 Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation

Haughey, C.; Mukherjee, D.; Steele, R.; Popple, A.; Dura-Perez, L.; Pickard, A.; Jain, S.; Mullan, P.; Williams, R.; Oliveira, P.; Buckley, N.; Honeychurch, J.; McDade, S. S.; Illidge, T.; Mills, I.; Eddie, S.

10.1101/2020.02.16.942789 — cancer biology — Posted on 2020-02-16

1752 AS-Quant: Detection and Visualization of Alternative Splicing Events with RNA-seq Data

Fahmi, N. A.; Yeh, H.-S.; Chang, J.-W.; Nassereddeen, H.; Fan, D.; Yong, J.; Zhang, W.

10.1101/2020.02.15.950287 — bioinformatics — Posted on 2020-02-16

1753 DGAT-onco: A powerful method to detect oncogenes by integrating differential mutational analysis and functional impacts of somatic mutations

Zhang, H.; Wei, J.; Liu, Z.; Liu, X.; Chong, Y.; Lu, Y.; Zhao, H.; Yang, Y.

10.1101/2020.02.15.947085 — bioinformatics — Posted on 2020-02-16

1754 Roles of the ClC chloride channel CLH-1 in food-associated salt chemotaxis behavior of C. elegans

Park, C.; Sakurai, Y.; Sato, H.; Kanda, S.; Iino, Y.; Kunitomo, H.

10.1101/2020.02.16.951368 — genomics — Posted on 2020-02-16

1755 Defensive forwards: stress-responsive proteins in cell walls of crop plants

Niu, L.; Wang, W.

10.1101/2020.02.15.950535 — bioinformatics — Posted on 2020-02-16

1756 The Safety of a Therapeutic Product Composed of a Combination of Stem Cell Released Molecules from Adipose Mesenchymal Stem Cells and Fibroblasts

Maguire, G.; Friedman, P.

10.1101/2020.02.14.950055 — bioengineering — Posted on 2020-02-16

1757 Promoter CpG density is predictive of downstream gene loss-of-function intolerance

Boukas, L.; Bjornsson, H. T.; Hansen, K. D.

10.1101/2020.02.15.936351 — genetics — Posted on 2020-02-16

1758 Why not record from every electrode with a CMOS scanning probe?

10.1101/275818 — neuroscience — Posted on 2020-02-16

1759 A fast linkage disequilibrium-based statistical test for Genome-Wide Epistatic Selection Scans in structured populations

Boyrie, L.; Moreau, C.; Frugier, F.; Jacquet, C.; Bonhomme, M.

10.1101/2020.02.14.949206 — genetics — Posted on 2020-02-16

1760 Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma

Feldman, H.; Toledo, C.; Arora, S.; Hoellerbauer, P.; Corrin, P.; Carter, L.; Kufeld, M.; Bolouri, H.; Basom, R.; Delrow, J.; McFaline-Figueroa, J.; Trapnell, C.; Pollard, S.; Patel, A.; Plaisier, C.; Paddison, P.

10.1101/446344 — cell biology — Posted on 2020-02-16

1761 RootDigger: a root placement program for phylogenetic trees

Bettisworth, B.; Stamatakis, A.

10.1101/2020.02.13.935304 — bioinformatics — Posted on 2020-02-16

1762 First report of the Eocene bivalve Schedocardia (Mollusca, Cardiidae) from Cuba

Orihuela, J.; Ceballos Izquierdo, Y.; Portell, R. W.

10.1101/2020.02.03.932756 — paleontology — Posted on 2020-02-16

1763 Readthrough errors purge deleterious cryptic sequences, facilitating the birth of coding sequences

Kosinski, L.; Masel, J.

10.1101/737452 — evolutionary biology — Posted on 2020-02-16

1764 Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development

Saiz, N.; Mora-Bitria, L.; Rahman, S.; George, H.; Herder, J. P.; Garcia-Ojalvo, J.; Hadjantonakis, A.-K.

10.1101/2019.12.27.889006 — developmental biology — Posted on 2020-02-16

1765 Prior short-term habituation to auditory feedback delays does not mitigate their disruptive effect on speech auditory-motor adaptation

Shiller, D.; Mitsuya, T.; Max, L.

10.1101/2020.02.15.951004 — neuroscience — Posted on 2020-02-16

1766 Categorical representation from sound and sight in the ventral occipito-temporal cortex of sighted and blind

Mattioni, S.; Rezk, M.; Battal, C.; Bottini, R.; Cuculiza Mendoza, K. E.; Oosterhof, N. N.; Collignon, O.

10.1101/719690 — neuroscience — Posted on 2020-02-16

1767 Completing Linneaus's inventory of the Swedish insect fauna: only 5,000 species left?

Ronquist, F.; Forshage, M.; Häggqvist, S.; Karlsson, D.; Hovmöller, R.; Bergsten, J.; Holston, K.; Britton, T.; Abenius, J.; Andersson, B.; Buhl, P. N.; Coulianos, C.-C.; Fjellberg, A.; Gertsson, C.-A.; Hellqvist, S.; Jaschhof, M.; Kjaerandsen, J.; Klopfstein, S.; Kobro, S.; Liston, A.; Meier, R.; Pollet, M.; Riedel, M.; Rohacek, J.; Schuppenhauer, M.; Stigenberg, J.; Struwe, I.; Taeger, A.; Ulefors, S.-O.; Varga, O.; Withers, P.; Gärdenfors, U.

10.1101/687392 — ecology — Posted on 2020-02-16

1768 Distinct natural syllable-selective neuronal ensembles in the primary auditory cortex of awake marmosets

huanhuan, Z.; Huang, J.-f.; Shen, Z.; Gong, N.; Wen, Y.-q.; Wang, L.; Poo, M.-m.

10.1101/2020.02.16.951194 — neuroscience — Posted on 2020-02-16

1769 Structure of the Lifeact F-actin complex

Belyy, A.; Merino, F.; Sitsel, O.; Raunser, S.

10.1101/2020.02.16.951269 — molecular biology — Posted on 2020-02-16

1770 Pou5f3 and Sox19b select gene expression repertoire at Zygotic Genome Activation

Gao, M.; Veil, M.; Rosenblatt, M.; Gebhard, A.; Haas, H.; Buryanova, L.; Yampolsky, L.; Gruening, B. A.; Timmer, J.; Onichtchouk, D.

10.1101/2020.02.16.949362 — developmental biology — Posted on 2020-02-16

1771 Long non-coding RNA Gm12664 up-regulates CAV1 expression to promote hepatocellular lipid accumulation by sponging miR-295-5p

xu, f.; Wang, L.; CHEN, L.; Zhang, Q.; xin, n. l.

10.1101/2020.02.15.951095 — molecular biology — Posted on 2020-02-16

1772 Sequential enrichment at the nuclear periphery of H2A.Zac and H3K9me2 accompanies pluripotency loss in human embryonicstem cells

Kafer, G. R.; Rillo-Bohn, R.; Carlton, P. M.

10.1101/2020.02.15.951103 — cell biology — Posted on 2020-02-16

1773 Novel Kras-mutant murine models of non-small cell lung cancer possessing co-occurring oncogenic mutations and increased tumor mutational burden

Salehi-Rad, R.; Li, R.; Tran, L. M.; Lim, R. J.; Abascal, J.; Momcilovic, M.; Park, S. J.; Ong, S. L.; Huang, Z. L.; Paul, M.; Shackelford, D. B.; Krysan, K.; Liu, B.; Dubinett, S. M.

10.1101/2020.02.15.950220 — cell biology — Posted on 2020-02-16

1774 Brown Adipose Tissue is Associated with Improved Cardiometabolic Health and Regulates Blood Pressure

Becher, T.; Palanisamy, S.; Kramer, D. J.; Marx, S. J.; Wibmer, A. G.; Del Gaudio, I.; Butler, S. D.; Jiang, C. S.; Vaughan, R.; Schoder, H.; Di Lorenzo, A.; Mark, A.; Cohen, P.

10.1101/2020.02.08.933754 — physiology — Posted on 2020-02-16

1775 Genetic variation and sex differences are missed opportunities for addiction biology.

Saul, M. C.; Bagley, J. R.; Bailey, L. S.; Datta, U.; Dickson, P. E.; Dodd, R.; Gagnon, L. H.; Kimble, V. M.; Leonardo, M.; Kim, S.-M.; Olson, A.; Roy, T.; Schoenrock, S. E.; Wilcox, T.; Jentsch, J. D.; Logan, R. W.; McClung, C. A.; Philip, V. M.; Reinholdt, L. G.; Rizzo, S. J. S.; Tarantino, L. M.; Chesler, E. J.

10.1101/2020.02.14.949784 — neuroscience — Posted on 2020-02-16

1776 Slightly beneficial genes are retained by evolving Horizontal Gene Transfer despite selfish elements

Dijk, B. v.; Hogeweg, P.; Doekes, H.; Takeuchi, N.

10.1101/2020.02.13.947077 — microbiology — Posted on 2020-02-16

1777 Targeting OCA-B/Pou2af1 blocks type-1 diabetes and reduces infiltration of activated, islet-reactive T cells

Kim, H.; Perovanovic, J.; Shakya, A.; Shen, Z.; German, C. N.; Ibarra, A.; Jafek, J.; Lin, N.-P.; Evavold, B. D.; Chou, D. H.- C.; Jensen, P. E.; He, X.; Tantin, D.

10.1101/2020.02.06.937839 — immunology — Posted on 2020-02-16

1778 Longitudinal analysis of naturally acquired antibodies to PfEMP1 CIDR domain variants and their association with malaria protection

Obeng-Adjei, N.; Larremore, D. B.; Turner, L.; Ongoiba, A.; Li, S.; Doumbo, S.; Yazew, T. B.; Kayentao, K.; Miller, L. H.; Traore, B.; Pierce, S. K.; Buckee, C. O.; Lavstsen, T.; Crompton, P. D.; Tran, T. M.

10.1101/2020.02.11.944330 — immunology — Posted on 2020-02-16

1779 No detectable alloreactive transcriptional responses during donor-multiplexed single-cell RNA sequencing of peripheral blood mononuclear cells

McGinnis, C. S.; Siegel, D. A.; Xie, G.; Stone, M.; Gartner, Z. J.; Roan, N. R.; Lee, S. A.

10.1101/2020.02.12.946509 — genomics — Posted on 2020-02-16

1780 Trophic guild and forest type explain phyllostomid bat abundance variation from human habitat disturbance.

Carballo-Morales, J. D.; Saldana-Vazquez, R. A.; Villalobos, F.

10.1101/2020.02.13.946889 — ecology — Posted on 2020-02-16

1781 Antibiotics affect migratory restlessness orientation

Werber, Y.; Natan, E.; Lavner, Y.; Vortman, Y.

10.1101/2020.02.14.949651 — animal behavior and cognition — Posted on 2020-02-16

1782 Prediction of meiosis-essential genes based upon the dynamic proteomes responsive to spermatogenesis

Fang, K.; Li, Q.; Wei, Y.; Shen, J.; Guo, W.; Zhou, C.; Wu, R.; Ying, W.; Yu, L.; Zi, J.; Zhang, Y.; Yang, H.; Liu, S.; Chen, C. D.

10.1101/2020.02.05.936435 — developmental biology — Posted on 2020-02-16

1783 The interaction of crossover formation and the dynamic architecture of the synaptonemal complex during meiosis

Köhler, S.; Wojcik, M.; Xu, K.; Dernburg, A.

10.1101/2020.02.16.947804 — cell biology — Posted on 2020-02-16

1784 Mountain stoneflies may tolerate warming streams: evidence from organismal physiology and gene expression

Hotaling, S.; Shah, A. A.; McGowan, K. L.; Tronstad, L. M.; Giersch, J. J.; Finn, D. S.; Woods, H. A.; Dillon, M. E.; Kelley, J. L.

10.1101/2019.12.16.878926 — physiology — Posted on 2020-02-16

1785 Frank-Starling law and Bowditch phenomenon may have the common theoretical grounds

Kamnev, Y.

10.1101/069609 — physiology — Posted on 2020-02-16

1786 A role for the Fem-1 gene of Drosophila melanogaster in adult courtship

Thies, M.; Berke, B.

10.1101/2020.01.19.911693 — neuroscience — Posted on 2020-02-16

1787 Affective biases encoded by the pupil-linked central arousal systems dynamically modulateinequality aversion in human interpersonal negotiations

Murphy, D. A.; Harmer, C. J.; Browning, M.; Pulcu, E.

10.1101/826529 — neuroscience — Posted on 2020-02-16

1788 The eNOS-dependent S-nitrosylation of the NF-κB subunit p65 has neuroprotective consequences in excitotoxicity

Caviedes, A.; Maturana, B.; Corvalan, K.; Engler, A.; Gordillo, F.; Varas-Godoy, M.; Smalla, K.-H.; Batiz, L. F.; Lafourcade, C. A.; Kaehne, T.; Wyneken, U.

10.1101/2020.02.04.932772 — neuroscience — Posted on 2020-02-16

1789 Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.

Cox, S. R.; Harris, M. A.; Ritchie, S. J.; Buchanan, C. R.; Valdes Hernandez, M. d. C.; Corley, J.; Taylor, A. M.; Madole, J. W.; Harris, S. E.; Whalley, H. C.; McIntosh, A. M.; Russ, T. C.; Bastin, M. E.; Wardlaw, J. M.; Deary, I. J.; Tucker-Drob, E. M.

10.1101/2020.01.19.911420 — neuroscience — Posted on 2020-02-16

1790 PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts

Piberger, A. L.; Bowry, A.; Kelly, R. D. W.; Walker, A. K.; Gonzalez, D.; Bailey, L. J.; Doherty, A. J.; Mendez, J.; Morris, J. R.; Bryant, H. E.; Petermann, E.

10.1101/773242 — molecular biology — Posted on 2020-02-16

1791 MAF1 is a Chronic Repressor of RNA Polymerase III Transcription in the Mouse

Bonhoure, N.; Praz, V.; Moir, R. D.; Willemin, G.; Mange, F.; Moret, C.; Willis, I. M.; Hernandez, N.

10.1101/775353 — molecular biology — Posted on 2020-02-16

1792 PrkA controls peptidoglycan biosynthesis through the essential phosphorylation of ReoM

Wamp, S.; Rutter, Z. J.; Rismondo, J.; Jennings, C. E.; Moeller, L.; Lewis, R. J.; Halbedel, S.

10.1101/2019.12.16.877605 — microbiology — Posted on 2020-02-16

1793 The insert sequence in SARS-CoV-2 enhances spike protein cleavage by TMPRSS

Meng, T.; Cao, H.; Zhang, H.; Kang, Z.; Xu, D.; Gong, H.; Wang, J.; Li, Z.; Cui, X.; Xu, H.; Wei, H.; Pan, X.; Zhu, R.; Xiao, J.; Zhou, W.; Cheng, L.; Liu, J.

10.1101/2020.02.08.926006 — microbiology — Posted on 2020-02-16

1794 T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex

Blumenthal, D.; Chandra, V.; Avery, L.; Burkhardt, J. K.

10.1101/680132 — immunology — Posted on 2020-02-16

1795 Immune cells lacking Y chromosome have widespread dysregulation of autosomal genes

Dumanski, J. P.; Halvardson, J.; Davies, H.; Rychlicka-Buniowska, E.; Mattisson, J.; Torabi Moghadam, B.; Nagy, N.; Weglarczyk, K.; Bukowska-Strakova, K.; Danielsson, M.; Olszewski, P.; Piotrowski, A.; Oerton, E.; Ambicka, A.; Przewoznik, M.; Belch, L.; Grodzicki, T.; Chlosta, P. L.; Imreh, S.; Giedraitis, V.; Kilander, L.; Nordlund, J.; Ameur, A.; Gyllensten, U.; Johansson, A.; Jozkowicz, A.; Siedlar, M.; Klich-Raczka, A.; Jaszczynski, J.; Enroth, S.; Baran, J.; Ingelsson, M.; Perry, J. R. B.; Rys, J.; Forsberg, L. A.

10.1101/673459 — immunology — Posted on 2020-02-16

1796 Genome-wide analysis in Drosophila reveals diet by gene interactions and uncovers diet-responsive genes

James, D. E.; Francis, D.; Ghazanfar, S.; Havula, E.; Krycer, J. R.; Senior, A.; Minard, A. Y.; Geddes, T. A.; Weiss, F.; Stoeckli, J.; Yang, J. Y. H.

10.1101/718304 — genetics — Posted on 2020-02-16

1797 Grandpaternal effects are lineage- and sex-specific in threespined sticklebacks

Hellmann, J. K.; Carlson, E. R.; Bell, A. M.

10.1101/796995 — evolutionary biology — Posted on 2020-02-16

1798 Sex-specific transgenerational plasticity in threespined sticklebacks

Hellmann, J. K.; Bukhari, S. A.; Deno, J.; Bell, A. M.

10.1101/763862 — evolutionary biology — Posted on 2020-02-16

1799 Epistasis, inbreeding depression and the evolution of self-fertilization

Abu Awad, D.; Roze, D.

10.1101/809814 — evolutionary biology — Posted on 2020-02-16

1800 Continual inactivation of genes involved in stem cell functional identity stabilizes progenitor commitment

Rives-Quinto, N.; Komori, H.; Janssens, D. H.; Kondo, S.; Dai, Q.; Moore, A. W.; Lee, C.-Y.

10.1101/2020.02.03.931972 — developmental biology — Posted on 2020-02-16

1801 Finding ranges of optimal transcript expression quantification in cases of non-identifiability

Ma, C.; Zheng, H.; Kingsford, C.

10.1101/2019.12.13.875625 — bioinformatics — Posted on 2020-02-16

1802 Hepatic Mitochondrial Remodeling is Mechanistically Linked to Insulin Resistance in Nonalcoholic Fatty Liver Disease

Shannon, C. E.; Ragavan, M.; Palavicini, J. P.; Fourcaudot, M.; Bakewell, T.; Jin, E. S.; Malloy, C. R.; Han, X.; Merritt, M. E.; Norton, L.

10.1101/2020.01.02.892992 — biochemistry — Posted on 2020-02-16

1803 A statistical nonparametric method for identifying consistently important features across samples

Sauerwald, N.; Kingsford, C.

10.1101/833624 — genomics — Posted on 2020-02-16

1804 Fitness functions, genetic and non-genetic inheritance, and why ecological dynamics and evolution are inevitably linked

Coulson, T.; Potter, T.; Felmy, A.

10.1101/762658 — evolutionary biology — Posted on 2020-02-16

1805 Targeting Cellular DNA Damage Responses: Predicting in vivo treatment responses using an in vitro-calibrated agent-based mathematical model

Hamis, S. J.; Yates, J.; Chaplain, M. A.; Powathil, G. G.

10.1101/841270 — cancer biology — Posted on 2020-02-16

1806 Reference-free deconvolution of complex DNA methylation data - a systematic protocol

Scherer, M.; Nazarov, P. V.; Toth, R.; Sahay, S.; Kaoma, T.; Maurer, V.; Plass, C.; Lengauer, T.; Walter, J.; Lutsik, P.

10.1101/853150 — bioinformatics — Posted on 2020-02-16

1807 Engineering and Evolution of Methanol Assimilation in Saccharomyces cerevisiae

Espinosa, M. I.; Gonzalez-Garcia, R. A.; Valgepea, K.; Plan, M.; Scott, C.; Pretorius, I. S.; Marcellin, E.; Paulsen, I. T.; Williams, T.

10.1101/717942 — synthetic biology — Posted on 2020-02-16

1808 Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense Mediated Decay as Modifiers of ALS C9orf72 Toxicity

Ortega, J. A.; Daley, E. L.; Kour, S.; Samani, M.; Tellez, L.; Hall, E. A.; Esengul, Y. T.; Tsai, Y.-H.; Gendron, T. F.; Donnelly, C. J.; Siddique, T.; Savas, J. N.; Pandey, U. B.; Kiskinis, E.

10.1101/677419 — neuroscience — Posted on 2020-02-16

1809 RIF1-Long promotes G1 phase 53BP1 nuclear bodies to protect against replication stress

Watts, L. P.; Natsume, T.; Saito, Y.; Garzon, J.; Kanemaki, M. T.; Hiraga, S.-i.; Donaldson, A. D.

10.1101/859199 — molecular biology — Posted on 2020-02-16

1810 The type VII secretion system protects Staphylococcus aureus against antimicrobial host fatty acids

Kengmo Tchoupa, A.; Watkins, K. E.; Jones, R. A.; Kuroki, A.; Alam, M. T.; Perrier, S.; Chen, Y.; Unnikrishnan, M.

10.1101/572172 — microbiology — Posted on 2020-02-16

1811 Polygenic risk score based on weight gain trajectories is a strong predictor of childhood obesity

Craig, S. J. C.; Kenney, A. M.; Lin, J.; Paul, I. M.; Birch, L. L.; Savage, J.; Marini, M. E.; Chiaromonte, F.; Reimherr, M. L.; Makova, K. D.

10.1101/606277 — genetics — Posted on 2020-02-16

1812 Ecological causes of speciation and species richness in mammals

Upham, N. S.; Esselstyn, J. A.; Jetz, W.

10.1101/504803 — evolutionary biology — Posted on 2020-02-16

1813 MODELLING THE IMPACT OF DISPERSAL ON A NATAL POPULATION THAT EXHIBITS BOOM-BUST DYNAMICS

Deere, J.; van den Berg, I.; Roth, G.; Smallegange, I.

10.1101/402198 — ecology — Posted on 2020-02-16

1814 BrainNET: Inference of brain network topology using Machine Learning

Murugesan, G. K.; Nalawade, S.; Bangalore Yogananda, C. G.; Davenport, E.; Wagner, B.; Kim, W. H.; Maldjian, J. A.

10.1101/776641 — bioengineering — Posted on 2020-02-16

1815 A single-parasite transcriptional atlas of Toxoplasma gondii reveals novel control of antigen expression

Xue, Y.; Theisen, T. C.; Rastogi, S.; Ferrel, A.; Quake, S. R.; Boothroyd, J. C.

10.1101/656165 — bioengineering — Posted on 2020-02-16

1816 Novel cyclic peptides in seed of Annona muricata are ribosomally synthesised

Fisher, M. F.; Zhang, J.; Berkowitz, O.; Whelan, J.; Mylne, J. S.

10.1101/647552 — biochemistry — Posted on 2020-02-16

1817 The Dementias Platform UK (DPUK) Data Portal

Bauermeister, S.; Orton, C.; Thompson, S.; Barker, R.; Bauermeister, J.; Ben-Shlomo, Y.; Brayne, C.; Burn, D.; Campbell, A.; Calvin, C.; Chandran, S.; Chaturvedi, N.; Chene, G.; Chessell, I.; Corbett, A.; Davis, D.; Denis, M.; DuFouil, C.; Elliott, P.; Fox, N.; Hill, D.; Hofer, S.; Hu, M.; Jindra, C.; Kee, F.; Kim, C.-H.; Kim, C.; Kivimaki, M.; Koychev, I.; Lawson, R.; Linden, G.; Lyons, R.; MacKay, C.; Matthews, P.; McGuiness, B.; Middleton, L.; Moody, C.; Moore, K.; Na, D. L.; O'Brien, J.; Ourselin, S.; Paranjothy, S.; Park, K. S.; Porteous, D.; Richards, M.; Ritchie, C.; Rohrer, J.; Rossor,

10.1101/582155 — neuroscience — Posted on 2020-02-16

1818 The covariance perceptron: A new paradigm for classification and processing of time series in recurrent neuronal networks

Gilson, M.; Dahmen, D.; Moreno-Bote, R.; Insabato, A.; Helias, M.

10.1101/562546 — neuroscience — Posted on 2020-02-16

1819 Improving the usability and comprehensiveness of microbial databases

Loeffler, C.; Karlsberg, A.; Martin, L. S.; Eskin, E.; Koslicki, D.; Mangul, S.

10.1101/497867 — bioinformatics — Posted on 2020-02-16

1820 Signal propagation via cortical hierarchies

Vazquez-Rodriguez, B.; Liu, Z.-Q.; Hagmann, P.; Misic, B.

10.1101/2020.02.15.950907 — neuroscience — Posted on 2020-02-16

1821 In and outs of Chuviridae endogenous viral elements: origin of a retrovirus and signature of ancient and ongoing arms race in mosquito genomes

Dezordi, F. Z.; Vasconcelos, C. R. d. S.; Rezende, A. M.; Wallau, G. d. L.

10.1101/2020.02.15.950899 — evolutionary biology — Posted on 2020-02-16

1822 Allosteric action of nucleotides on Hsp90 across several time- and length scales

Wolf, S.; Sohmen, B.; Hellenkamp, B.; Thurn, J.; Stock, G.; Hugel, T.

10.1101/2020.02.15.950725 — biophysics — Posted on 2020-02-16

1823 Non-photopic and photopic visual cycles differentially regulate immediate, early and late-phases of cone photoreceptor-mediated vision

Ward, R.; Kaylor, J. J.; Cobice, D. F.; Pepe, D. A.; McGarrigle, E. M.; Brockerhoff, S. E.; Hurley, J. B.; Travis, G. H.; Kennedy, B. N.

10.1101/2020.02.15.950915 — biochemistry — Posted on 2020-02-16

1824 Histogenesis of the reticulum of non- descript goat (Capra hircus) of India

Gupta, V.; Farooqui, M. M.; Sharma, A. P.; Pathak, A.

10.1101/2020.02.14.950311 — developmental biology — Posted on 2020-02-15

1825 Model Reduction Tools For Phenomenological Modeling of Input-Controlled Biological Circuits

Pandey, A.; Murray, R. M.

10.1101/2020.02.15.950840 — synthetic biology — Posted on 2020-02-15

1826 Disulfide bridge formation prevents CaMKII/Calmodulin interaction in Parkinson's disease

Di Maio, R.; General, I. J.; Furbee, E.; Ayoobc, J. C.; Castro, S. L.; Bahar, I.; Greenamyre, J. T.; Pullara, F.

10.1101/2020.02.14.947960 — neuroscience — Posted on 2020-02-15

1827 Oecophyllibacter saccharovorans gen. nov. sp. nov., a bacterial symbiont of the weaver ant Oecophylla smaragdina with a plasmid-borne sole rrn operon

Chua, K.-O.; See-Too, W.-S.; Tan, J.-Y.; Song, S.-L.; Yong, H.-S.; Yin, W.-F.; Chan, K.-G.

10.1101/2020.02.15.950782 — microbiology — Posted on 2020-02-15

1828 Seneca Valley virus intercellular transmission mediated by exosomes

Zhang, K.; Xu, G.; Xu, S.; Shi, X.; Shen, C.; Hao, J.; Yan, M.; Zhang, D.; Liu, X.-T.; Zheng, H.

10.1101/2020.02.14.950345 — immunology — Posted on 2020-02-15

1829 The hotter, the better: warmer winters boost the natural spread of an eastern Mediterranean bumblebee (Hymenoptera: Apidae: Bombus haematurus)

Biella, P.; Cetkovic, A.; Gogala, A.; Neumayer, J.; Sarospataki, M.; Sima, P.; Smetana, V.

10.1101/2020.02.15.950931 — ecology — Posted on 2020-02-15

1830 The significance of mitochondrial DNA half-life to the lifespan of post-mitotic cells

Holt, A. G.; Davies, A. M.

10.1101/2020.02.15.950410 — cell biology — Posted on 2020-02-15

1831 Pharmacological tuning of microRNA in FAP-derived Extracellular Vesicles by HDAC inhibitors promotes regeneration and reduces fibrosis in dystrophic muscles.

Sandona, M.; Consalvi, S.; Tucciarone, L.; De Bardi, M.; Scimeca, M.; Angelini, D. F.; Buffa, V.; D'Amico, A.; Bertini, E. S.; Cazzaniga, S.; Bettica, P.; Bouche, M.; Bongiovanni, A.; Puri, P. L.; Saccone, V.

10.1101/2020.02.15.947325 — cell biology — Posted on 2020-02-15

1832 Modeling and Analysis of the Macronutrient Signaling Network in Budding Yeast

Jalihal, A. P.; Kraikivski, P.; Murali, T. M.; Tyson, J.

10.1101/2020.02.15.950881 — systems biology — Posted on 2020-02-15

1833 The Association of Externalizing and Internalizing Problems with Indicators of Intelligence in a Sample of At-Risk Children

Kavish, N.; Helton, J.; Vaughn, M.; Boutwell, B. B.

10.1101/210500 — neuroscience — Posted on 2020-02-15

1834 Analysis of variance when both input and output sets are high-dimensional

de los Campos, G. A.; Torsten, P.; Gonzalez-Raymundez, A.; Simianer, H.; Mias, G.; Vazquez, A. I.

10.1101/2020.02.15.950949 — genomics — Posted on 2020-02-15

1835 Emergence and diversification of a highly invasive chestnut pathogen lineage across south-eastern Europe

Stauber, L.; Prospero, S.; Croll, D.

10.1101/2020.02.15.950170 — evolutionary biology — Posted on 2020-02-15

1836 LC/MS-QToF Profiling, Anti-Diabetic and Anti-Adipogenic potential of Divya MadhuKalp: A Novel Herbo-mineral Formulation

Joshi, A.; Das, S. K.; Bisht, L.; Sakat, S.; Sharma, V.; Sharma, N.; Joshi, K.; Verma, S.; Sharma, V. K.; Balkrishna, A.; Joshi, C. S.

10.1101/2020.02.15.950865 — cell biology — Posted on 2020-02-15

1837 Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers fluorobiphenylglutamine

Baguet, T.; Verhoeven, J.; Pauwelyn, G.; Hu, J.; Lambe, P.; De Lombaerde, S.; Piron, S.; Donche, S.; Descamps, B.; Goethals, I.; Vanhove, C.; De Vos, F.; Beyzavi, M. H.

10.1101/2020.02.14.948372 — cancer biology — Posted on 2020-02-15

1838 A Bayesian nonparametric approach to super-resolution single-molecule localization

Gabitto, M. I.; Marie-Nellie, H.; Pakman, A.; Pataki, A.; Darzacq, X.; Jordan, M.

10.1101/2020.02.15.950873 — bioinformatics — Posted on 2020-02-15

1839 A novel voltage clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels.

Gaete, P. S.; Lillo, M. A.; Lopez, W.; Liu, Y.; Harris, A. L.; Contreras, J. E.

10.1101/2020.02.15.950923 — biophysics — Posted on 2020-02-15

1840 Dissociable neural information dynamics of perceptual integration and differentiation during bistable perception

Canales-Johnson, A.; Billig, A.; Olivares, F.; Gonzalez, A.; Garcia, M. d. C.; Silva, W.; Ciraolo, C.; Vaucheret, E.; Mikulan, E.; Ibanez, A.; Huepe, D.; Chennu, S.; Bekinschtein, T.

10.1101/133801 — neuroscience — Posted on 2020-02-15

1841 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations

Panyard, D. J.; Kim, K. M.; Darst, B. F.; Deming, Y. K.; Zhong, X.; Wu, Y.; Kang, H.; Carlsson, C. M.; Johnson, S. C.; Asthana, S.; Engelman, C. D.; Lu, Q.

10.1101/2020.02.14.948398 — genomics — Posted on 2020-02-15

1842 Parvalbumin+ and Npas1+ Pallidal Neurons Have Distinct Circuit Topology and Function

Pamukcu, A.; Cui, Q.; Xenias, H.; Berceau, B.; Augustine, E.; Fan, I.; Hantman, A.; Lerner, T.; Boca, S.; Chan, S.

10.1101/2020.02.14.950006 — neuroscience — Posted on 2020-02-15

1843 Path integration changes as a cognitive marker for vascular cognitive impairment? - a pilot study

Lowry, E.; Puthusseryppady, V.; Coughlan, G.; Jeffs, S.; Hornberger, M.

10.1101/2020.02.15.950675 — neuroscience — Posted on 2020-02-15

1844 Angiopathy with impaired glucose logistics observed in schizophrenia-like model mice

Hirai, S.; Miwa, H.; Tanaka, T.; Toriumi, K.; Kunii, Y.; Hino, M.; Izumi, R.; Nagaoka, A.; Yabe, H.; Nakamachi, T.; Shioda, S.; Dan, T.; Miyata, T.; Nishito, Y.; Suzuki, K.; Miyashita, M.; Itokawa, M.; Arai, M.; Okado, H.

10.1101/2020.02.14.939546 — neuroscience — Posted on 2020-02-15

1845 Temporal discounting in adolescents and adults with Tourette syndrome

Schueller, C. B.; Wagner, B. J.; Schueller, T.; Baldermann, J.; Huys, D.; Kerner, J.; Niessen, E.; Muenchau, A.; Brandt, V.; Peters, J.; Kuhn, J.

10.1101/2020.02.14.947812 — neuroscience — Posted on 2020-02-15

1846 Enteric glia as a source of neural progenitors in adult zebrafish

McCallum, S.; Obata, Y.; Fourli, E.; Boeing, S.; Peddie, C. J.; Xu, Q.; Horswell, S.; Kelsh, R.; Collinson, L.; Wilkinson, D.; Pin, C.; Pachnis, V.; Heanue, T.

10.1101/2020.02.14.949859 — neuroscience — Posted on 2020-02-15

1847 Diversity of culturable actinobacteria producing protease inhibitors from the intertidal zones of Maharashtra, India

Shintre, N. A.; Tamhane, V. A.; Deshpande, N. M.; Baig, U.; Pund, A.; Patwardhan, R.

10.1101/2020.02.14.949438 — microbiology — Posted on 2020-02-15

1848 High-quality de novo genome assembly of Kappaphycus alvarezii based on both PacBio and HiSeq sequencing

Jia, S.; Wang, G.; Liu, G.; Qu, J.; Zhao, B.; Jin, X.; Zhang, L.; Yin, J.; Liu, C.; Shan, G.; Wu, S.; Song, L.; Liu, T.; Wang, X.; Yu, J.

10.1101/2020.02.15.950402 — genomics — Posted on 2020-02-15

1849 Parkinsons disease determinants, prediction and gene-environment interactions in the UK Biobank

Jacobs, B. M.; Belete, D.; Bestwick, J. P.; Blauwendraat, C.; Bandres Ciga, S.; Heilbron, K.; Dobson, R.; Nalls, M. A.; Singleton, A.; Hardy, J.; Giovannoni, G.; Lees, A.; Schrag, A.; International Parkinson's Disease Genomics Consortium, ; Noyce, A.

10.1101/2020.02.15.950733 — genetics — Posted on 2020-02-15

1850 RNAAgeCalc: A multi-tissue transcriptional age calculator

Ren, X.; Kuan, P. F.

10.1101/2020.02.14.950188 — bioinformatics — Posted on 2020-02-15

1851 Suppressing peatland methane production by electron snorkeling through pyrogenic carbon

Sun, T.; Guzman, J. J. L.; Seward, J. D.; Enders, A.; Yavitt, J. B.; Lehmann, J.; Angenent, L. T.

10.1101/2020.02.15.950451 — microbiology — Posted on 2020-02-15

1852 Helicobacter small RNA regulates host adaptation and carcinogenesis

10.1101/2020.02.15.950279 — microbiology — Posted on 2020-02-15

1853 Integrin Affinity Modulation Critically Regulates Atherogenic Endothelial Activation in vitro and in vivo

Al Yafeai, Z.; Peretik, J. M.; Pearson, B. H.; Bhattarai, U.; Wang, D.; Petrich, B. G.; Orr, A. W.

10.1101/2020.02.14.949941 — cell biology — Posted on 2020-02-15

1854 Effects of Sodium tanshinone IIA sulfonate on H9C2 cardiomyocyte injury induced by sodium arsenite

Yue, Z.; Li, X. H.; Sheng, Z. X.; Jing, D. W.; Yan, W. X.; You, T. H.; Jian, D.; Hua, X. J.

10.1101/2020.02.14.948505 — cell biology — Posted on 2020-02-15

1855 GPU accelerated partial order multiple sequencealignment for long reads self-correction

Peverelli, F.; Di Tucci, L.; Santambrogio, M. D.; Ding, N.; Hofmeyr, S.; Buluc, A.; Oliker, L.; Yelick, K.

10.1101/2020.02.14.946939 — bioinformatics — Posted on 2020-02-15

1856 Tornadic shear stress induces a transient, calcineurin-dependent hyper-virulent phenotype in Mucorales molds

Wurster, S.; Tatara, A. M.; Albert, N. D.; Ibrahim, A. S.; Heitman, J.; Lee, S. C.; Shetty, A. C.; McCracken, C.; Graf, K. T.; Mikos, A. G.; Bruno, V. M.; Kontoyiannis, D. P.

10.1101/2020.02.14.945998 — microbiology — Posted on 2020-02-15

1857 Single Chlamydomonas reinhardi (C. reinhardtii) cell separation from bacterial cells and auto-fluorescence tracking with a nano-sieve device

Korensky, G.; Chen, X.; Bao, M.; Miller, A.; Lapizco-Encinas, B.; Park, M.; Du, K.

10.1101/2020.02.14.949867 — bioengineering — Posted on 2020-02-15

1858 The Streptomyces volatile 3-octanone alters auxin/cytokinin and growth in Arabidopsis thaliana via the gene family KISS ME DEADLY

Dotson, B. R.; Verschut, V.; Flardh, K.; Becher, P. G.; Rasmusson, A. G.

10.1101/2020.02.15.949685 — plant biology — Posted on 2020-02-15

1859 Autophagy is induced during plant grafting for wound healing

Kurotani, K.-i.; Tabata, R.; Kawakatsu, Y.; Sugita, R.; Okayasu, K.; Tanoi, K.; Notaguchi, M.

10.1101/2020.02.14.949453 — plant biology — Posted on 2020-02-15

1860 Central vestibular tuning arises from patterned convergence of otolith afferents

Liu, Z.; Kimura, Y.; Higashijima, S.-i.; Hildebrand, D.; Morgan, J.; Holy, T.; Bagnall, M. W.

10.1101/2020.02.14.948356 — neuroscience — Posted on 2020-02-15

1861 A meiosis-specific factor MRM/C19orf57 modulates localization of RAD51 and DMC1 recombinases to DSBs in mouse meiotic recombination

Ishiguro, K.-i.; Takemoto, K.; Tani, N.; Takada, Y.; Fujimura, S.; Tanno, N.; Yamane, M.; Okamura, K.; Sugimoto, M.; Araki, K.

10.1101/2020.02.14.950204 — molecular biology — Posted on 2020-02-15

1862 Voltage-gated ion channels mediate the electrotaxis of glioblastoma cells in a hybrid PMMA/PDMS microdevice

Tsai, H.-F.; IJspeert, C.; Shen, A. Q.

10.1101/2020.02.14.948638 — cell biology — Posted on 2020-02-15

1863 SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

Vaz, B.; Ruggiano, A.; Popovic, M.; Rodriguez-Berriguete, G.; Kilgas, S.; Singh, A. N.; Torrecilla, I.; Higgins, G.; Kiltie, A.; Ramadan, K.

10.1101/2020.02.14.949289 — cell biology — Posted on 2020-02-15

1864 The inner scaffold protects from centriole fracture

Steib, E.; Gambarotto, D.; Laporte, M. H.; Olieric, N.; Zheng, C.; Borgers, S.; Olieric, V.; Le Guennec, M.; Koll, F.; Tassin, A.-M.; Steinmetz, M. O.; Hamel, V.; Guichard, P.

10.1101/2020.02.15.950444 — cell biology — Posted on 2020-02-15

1865 Revealing Atomic-scale Molecular Diffusion of a Plant Transcription Factor WRKY domain protein along DNA

Dai, L.; Xu, Y.; Du, Z.; Su, X.-d.; Yu, J.

10.1101/2020.02.14.950295 — biophysics — Posted on 2020-02-15

1866 Open microfluidic coculture reveals paracrine signaling from human kidney epithelial cells promotes kidney specificity of Endothelial Cells

Zhang, T.; Lih, D.; Nagao, R.; Xue, J.; Berthier, E.; Himmelfarb, J.; Zheng, Y.; Theberge, A. B.

10.1101/2020.02.14.949776 — bioengineering — Posted on 2020-02-15

1867 In vivo multi-dimensional information-keeping in Halobacterium salinarum

Davis, J.; Bisson-Filho, A.; Kadyrov, D.; De Kort, T.; Biamonte, M.; Thattai, M.; Thutupalli, S.; Church, G.

10.1101/2020.02.14.949925 — synthetic biology — Posted on 2020-02-15

1868 Skeletonization of Plant Point Cloud Data in Stochastic Optimization Framework

Chaudhury, A.; Godin, C.

10.1101/2020.02.15.950519 — plant biology — Posted on 2020-02-15

1869 Biomarkers of Depression Symptoms Defined by Direct Intracranial Neurophysiology

Scangos, K. W.; Khambhati, A. N.; Daly, P. M.; Owen, L. L. W.; Manning, J. R.; Ambrose, J. B.; Austin, E.; Krystal, A. D.; Chang, E. F.

10.1101/2020.02.14.943118 — neuroscience — Posted on 2020-02-15

1870 Cell-cell communication through FGF4 generates and maintains robust proportions of differentiated cell fates in embryonic stem cells

Raina, D.; Stanoev, A.; Bahadori, A.; Protzek, M.; Koseska, A.; Schröter, C.

10.1101/2020.02.14.949701 — developmental biology — Posted on 2020-02-15

1871 PDH Mediated Mitochondrial Respiration Controls the Speed of Muscle Stem Cell Activation in Muscle Repair and Aging

Raval, M. H.; Cheng, P.-C.; Guardino, N.; Ahsan, S.; Zhou, H.; Tiwari, R. L.; Wang, L.; Chareunsouk, A.; Ederer, M.; Hwang, A. B.; Ellenberger, M.; Pepin, R.; Pormislow, D.; Shen, K.; Brack, A. S.; Rodgers, J. T.

10.1101/2020.02.14.950162 — cell biology — Posted on 2020-02-15

1872 RanBP2-mediated SUMOylation promotes human DNA polymerase lambda nuclear localization and DNA repair

Moreno-Onate, M.; Herrero-Ruiz, A. M.; Garcia-Dominguez, M.; Cortes-Ledesma, F.; Ruiz, J. F.

10.1101/2020.02.14.949644 — biochemistry — Posted on 2020-02-15

1873 Faster than thought: Detecting sub-second activation sequences with sequential fMRI pattern analysis

Wittkuhn, L.; Schuck, N. W.

10.1101/2020.02.15.950667 — neuroscience — Posted on 2020-02-15

1874 MCT2 Overexpression Rescues Metabolic Vulnerability and Protects Retinal Ganglion Cells in Two Models of Glaucoma

Harun-Or-Rashid, M.; Pappenhagen, N.; Zubricky, R.; Coughlin, L.; Jassim, A. H.; Inman, D. M.

10.1101/2020.02.14.950097 — neuroscience — Posted on 2020-02-15

1875 Pre-existing resistant proviruses can compromise maintenance of remission by VRC01 in chronic HIV-1 infection

Saha, A.; Dixit, N. M.

10.1101/2020.02.14.940395 — microbiology — Posted on 2020-02-15

1876 Phenotypic functional activities of monocyte change during crosstalk with breast cancer cell and enhancing effect of metformin of IFN-γ-associated antitumor cytokine production.

Dahmani, Z.; Addou-Klouche, L.; Gizard, F.; Dahou, S.; Messaoud, A.; Chahinez Djebri, N.; Idris Benaissti, M.; Mostefaoui, M.; Terbeche, H.; Nouari, W.; Miliani, M.; Lefranc, G.; Fernandez, A.; Lamb, N. J.; Aribi, M.

10.1101/2020.02.14.949412 — immunology — Posted on 2020-02-15

1877 mTOR complex 1 and 2 regulate S6 kinase 1 activation in tandem.

Majeed, S. T.; Batool, A.; Majeed, R.; Bhat, N. N.; Andrabi, K. I.

10.1101/2020.02.15.944892 — cell biology — Posted on 2020-02-15

1878 Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

Gnanapradeepan, K.; Basu, S.; Barnoud, T.; Leu, J. I.-J.; Good, M.; Lee, J. V.; Quinn, W. J.; Kung, C.-P.; Ahima, R. S.; Baur, J. A.; Wellen, K. E.; Liu, Q.; Schug, Z. T.; George, D. L.; Murphy, M. E.

10.1101/2020.02.14.946269 — cancer biology — Posted on 2020-02-15

1879 Viral channelrhodopsins: calcium-dependent Na+/K+ selective light-gated channels

Zabelskii, D.; Alekseev, A.; Kovalev, K.; Oliveira, A.-S.; Balandin, T.; Soloviov, D.; Bratanov, D.; Volkov, D.; Vaganova, S.; Astashkin, R.; Chizhov, I.; Yutin, N.; Rulev, M.; Popov, A.; Rokitskaya, T.; Antonenko, Y.; Rosselli, R.; Rodriguez-Valera, F.; Armeev, G.; Shaitan, K.; Bueldt, G.; Vivaudou, M.; Kirpichnikov, M.; Koonin, E. V.; Bamberg, E.; Gordeliy, V.

10.1101/2020.02.14.949966 — biophysics — Posted on 2020-02-15

1880 2MV/cm Pulsed Electric Fields Promote Transthyretin Amyloid Disintegration

Urabe, G.; Sato, T.; Nakamura, G.; Kobashigawa, Y.; Morioka, H.; Katsuki, S.

10.1101/2020.02.15.950501 — biophysics — Posted on 2020-02-15

1881 Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves

Frasca, A.; Xue, Y.; Kossar, A. P.; Keeney, S.; Rock, C.; Zakharchenko, A.; Streeter, M.; Gorman, R. C.; Grau, J. B.; George, I.; Bavaria, J. E.; Krieger, A.; Spiegel, D.; Levy, R. J.; Ferrari, G.

10.1101/2020.02.14.948075 — bioengineering — Posted on 2020-02-15

1882 Structural basis of substrate recognition and catalysis by fucosyltransferase 8

Jarva, M. A.; Dramicanin, M.; Lingford, J. P.; Mao, R.; John, A.; Jarman, K.; Grinter, R. W.; Goddard-Borger, E. D.

10.1101/2020.02.14.949818 — biochemistry — Posted on 2020-02-15

1883 Quantitative Proteomics and Phosphoproteomics Supports a Role for Mut9-Like Kinases in Multiple Metabolic and Signaling Pathways in Arabidopsis

Nusinow, D. A.; Wilson, M. E.; Tzeng, S.-C.; Augustin, M. M.; Evans, B. S.; Kutchan, T. M.; Choi, J. H.; Rogers, J. C.; Meyer, M.; Jiang, X.

10.1101/2020.02.14.950030 — plant biology — Posted on 2020-02-15

1884 Alterations in the intrinsic properties of striatal cholinergic interneurons after dopamine lesion and chronic L-DOPA

Choi, S. J.; Ma, T.; Ding, Y.; Cheung, T.; Joshi, N.; Sulzer, D.; Mosharov, E.; Kang, U. J.

10.1101/2020.02.14.950022 — neuroscience — Posted on 2020-02-15

1885 The binding of palonosetron and other antiemetic drugs to the serotonin 5-HT3 receptor

Zarkadas, E.; Zhang, H.; Cai, W.; Effantin, G.; Perot, J.; Neyton, J.; Chipot, C.; Schoehn, G.; Dehez, F.; Nury, H.

10.1101/2020.02.14.947937 — neuroscience — Posted on 2020-02-15

1886 Long-term implicit memory for sequential auditory patterns in humans

Bianco, R.; Harrison, P. M. C.; Hu, M.; Bolger, C.; Picken, S.; Pearce, M. T.; Chait, M.

10.1101/2020.02.14.949404 — neuroscience — Posted on 2020-02-15

1887 Genetic variation and sex differences are missed opportunities for addiction biology.

10.1101/2020.02.14.949784 — neuroscience — Posted on 2020-02-15

1888 Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of Erythropoietic Protoporphyria

Halloy, F.; Iyer, P. S.; Cwiek, P.; Ghidini, A.; Barman-Aksözen, J.; Wildner-Verhey van Wijk, N.; Theocharides, A.; Minder, E.; Schneider-Yin, X.; Schümperli, D.; Hall, J.

10.1101/2020.02.14.949297 — molecular biology — Posted on 2020-02-15

1889 Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation

Wrapp, D.; Wang, N.; Corbett, K. S.; Goldsmith, J. A.; Hsieh, C.-L.; Abiona, O.; Graham, B. S.; McLellan, J. S.

10.1101/2020.02.11.944462 — microbiology — Posted on 2020-02-15

1890 Genome-Wide Identification of Epigenetic Regulators in Quercus suber

Silva, H. S. G.; Sobral, R. S.; Magalhaes, A.; Cecilio, L. M.; Costa, M. M. R.

10.1101/2020.02.15.948950 — genomics — Posted on 2020-02-15

1891 Infrared heater warming system markedly reduces dew formation: An overlooked factor in arid ecosystems

FENG, T.; Zhang, L.; Chen, Q.; Ma, Z.; Wang, H.; Shangguan, Z.; Wang, L.; He, J.-S.

10.1101/2020.02.15.950584 — ecology — Posted on 2020-02-15

1892 Nutrient parsimony shapes diversity and functionality in hyper-oligotrophic Antarctic soils

Van Goethem, M. W.; Vikram, S.; Hopkins, D. W.; Hall, G.; Woodborne, S.; Aspray, T. J.; Hogg, I. D.; Cowan, D. A.; Makhalanyane, T. P.

10.1101/2020.02.15.950717 — ecology — Posted on 2020-02-15

1893 In Silico identification of potential drug targets by subtractive genome analysis of Enterococcus faecium DO.

Karim, M.; Islam, M. N.; Jewel, G. M. N. A.

10.1101/2020.02.14.948232 — bioinformatics — Posted on 2020-02-15

1894 DeepHE: Accurately Predicting Human Essential Genes based on Deep Learning

Zhang, X.; Xiao, W.; Xiao, W.

10.1101/2020.02.14.950048 — bioinformatics — Posted on 2020-02-15

1895 Faster and better CRISPR guide RNA design with the Crackling method

Bradford, J.; Chappell, T.; Perrin, D.

10.1101/2020.02.14.950261 — bioinformatics — Posted on 2020-02-15

1896 In vitro biosynthesis of poly-β-1,4-glucan derivatives using a promiscuous glycosyltransferase

Bulmer, G. S.; Mattey, A. P.; Parmeggiani, F.; Williams, R.; Ledru, H.; Marchesi, A.; Seibt, L. S.; Both, P.; Huang, K.; Galan, M. C.; Flitsch, S.; Green, A. P.; van Munster, J. M.

10.1101/2020.02.14.949545 — biochemistry — Posted on 2020-02-15

1897 Genome-wide identification of binding sites of GRHL2 in luminal-like and basal A subtypes of breast cancer

Danen, E. H.; Wang, Z.; Wu, H.; Daxinger, L.

10.1101/2020.02.13.946947 — cancer biology — Posted on 2020-02-14

1898 Bicaudal C is required for the function of the follicular epithelium during oogenesis in Rhodnius prolixus

Pascual, A.; Vilardo, E. S.; Taibo, C.; Sabio y Garcia, J.; Rivera-Pomar, R.

10.1101/2020.02.14.949222 — developmental biology — Posted on 2020-02-14

1899 Maternal arterial blood values during delivery: effect of mode of delivery, maternal characteristics, obstetric interventions and correlation to fetal umbilical cord blood

Zaigham, M.; Helfer, S.; Kristensen, K. H.; Isberg, P.-E.; Wiberg, N.

10.1101/2020.02.14.950089 — biochemistry — Posted on 2020-02-14

1900 Precise automatic classification of 46 different pollen types with convolutional neural networks

Sevillano, V.; Holt, K.; Aznarte, J. L.

10.1101/2020.02.14.949149 — plant biology — Posted on 2020-02-14

1901 Sentinel Interaction Mapping (SIM) - A generic approach for the functional analysis of human disease gene variants using yeast

Young, B.; Post, K. L.; Chao, J. T.; Meili, F.; Haas, K.; Loewen, C.

10.1101/2020.02.14.949198 — genomics — Posted on 2020-02-14

1902 PEA15 loss of function and defective cerebral development in the domestic cat

Barsh, G.; Graff, E.; Cochran, N.; Kaelin, C.; Day, K.; Prokop, J.; Gray-Edwards, H.; Watanabe, R.; Koehler, J.; Falgoust, R.; Martin, D.; Myers, R.; Cox, N.

10.1101/2020.02.14.949214 — genetics — Posted on 2020-02-14

1903 A fast linkage disequilibrium-based statistical test for Genome-Wide Epistatic Selection Scans in structured populations

Bonhomme, M.; Boyrie, L.; Jacquet, C.; Moreau, C.; Frugier, F.

10.1101/2020.02.14.949206 — genetics — Posted on 2020-02-14

1904 Buffering and total calcium levels determine the presence of oscillatory regimes in cardiac cells

Marchena, M.; Echebarria, B.; Shiferaw, Y.; Alvarez-Lacalle, E.

10.1101/2020.02.14.949180 — biophysics — Posted on 2020-02-14

1905 Refinement of protein structure via contact based potentials in replica exchange simulations

Schug, A.; Weiel, M.; Voronin, A.

10.1101/2020.02.14.949172 — biophysics — Posted on 2020-02-14

1906 Intuitive physical reasoning about objects' masses transfers to a visuomotor decision task consistent with Newtonian physics

Neupaertl, N.; Tatai, F.; Rothkopf, C. A.

10.1101/2020.02.14.949164 — animal behavior and cognition — Posted on 2020-02-14

1907 Population genomics of louping ill virus provide new insights into the evolution of tick-borne flaviviruses

Clark, J. J.; Gilray, J.; Orton, R. J.; Baird, M.; Wilkie, G. S.; da Silva Filipe, A.; Johnson, N.; McInnes, C. J.; Kohl, A.; Biek, R.

10.1101/2020.02.14.949230 — evolutionary biology — Posted on 2020-02-14

1908 Identification of a pangolin niche for a 2019-nCoV-like coronavirus through an extensive meta-metagenomic search

Wahba, L.; Jain, N.; Fire, A. Z.; Shoura, M. J.; Artiles, K. L.; McCoy, M. J.; Jeong, D. E.

10.1101/2020.02.08.939660 — bioinformatics — Posted on 2020-02-14

1909 Suppressive recurrent and feedback computations for adaptive processing in the human brain

Zamboni, E.; Kemper, V. G.; Goncalves, N. R.; Jia, K.; Bell, S. J.; Karlaftis, V. M.; Giorgio, J. J.; Rideaux, R.; Goebel, R.; Kourtzi, Z.

10.1101/2020.02.14.947895 — neuroscience — Posted on 2020-02-14

1910 Tol-Pal system and Rgs proteins interact to promote unipolar growth and cell division in Sinorhizobium meliloti

Krol, E.; Yau, H.; Lechner, M.; Schäper, S.; Bange, G.; Vollmer, W.; Becker, A.

10.1101/2020.02.13.948760 — microbiology — Posted on 2020-02-14

1911 Fenbendazole controls in vitro growth, virulence potential and animal infection in the Cryptococcusmodel

Oliveira, H. C. d.; Joffe, L.; Simon, K.; Castelli, R.; Reis, F.; Bryan, A.; Borges, B.; Soares Medeiros, L. C.; Bocca, A. L.; Del Poeta, M.; Rodrigues, M.

10.1101/2020.02.13.948745 — microbiology — Posted on 2020-02-14

1912 Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions

Schotanus, K.; Heitman, J.

10.1101/526962 — genetics — Posted on 2020-02-14

1913 Dynamic regulation of JAK-STAT signaling through the prolactin receptor predicted by computational modeling

Mortlock, R. D.; Georgia, S. K.; Finley, S. D.

10.1101/2020.02.14.949321 — systems biology — Posted on 2020-02-14

1914 Network analysis identifies regulators of lineage-specific phenotypes in Mycobacterium tuberculosis

Banaei-Esfahani, A.; Trauner, A.; Borrell Farnov, S.; Gygli, S. M.; Rustad, T. R.; Feldmann, J.; Gillet, L. C.; Schubert, O. T.; Sherman, D. R.; Beisel, C.; Gagneux, S.; Aebersold, R.; Collins, B. C.

10.1101/2020.02.14.943365 — systems biology — Posted on 2020-02-14

1915 Generating individual aging trajectories with a network model using cross-sectional data

Farrell, S.; Mitnitski, A.; Rockwood, K.; Rutenberg, A.

10.1101/2020.02.14.949560 — systems biology — Posted on 2020-02-14

1916 Accelerated Simulations of Chemical Reaction Systems using the Stochastic Simulation Algorithm on GPUs

Pino, J. C.; Prugger, M.; Lubbock, A. L. R.; Harris, L. A.; Lopez, C. F.

10.1101/2020.02.14.948612 — systems biology — Posted on 2020-02-14

1917 Steroid hormone agonists reduce female fitness in insecticide-resistant Anopheles populations

Brown, F.; Paton, D. G.; Catteruccia, F.; Ranson, H.; Ingham, V. A.

10.1101/2020.02.14.949024 — pharmacology and toxicology — Posted on 2020-02-14

1918 Network efficiency predicts resilience to cognitive decline in elderly at risk for Alzheimer's

Fischer, F. U.; Wolf, D.; Fellgiebel, A.

10.1101/2020.02.14.949826 — neuroscience — Posted on 2020-02-14

1919 Coordinated Interaction: A model and test for globally signed epistasis in complex traits

Sheppard, B.; Rappoport, N.; Loh, P.-R.; Sanders, S. J.; Dahl, A.; Zaitlen, N.

10.1101/2020.02.14.949883 — genetics — Posted on 2020-02-14

1920 Identification of a pangolin niche for a 2019-nCoV-like coronavirus through an extensive meta-metagenomic search

Wahba, L.; Jain, N.; Fire, A. Z.; Artiles, K. L.; McCoy, M. J.; Jeong, D. E.

10.1101/2020.02.08.939660 — bioinformatics — Posted on 2020-02-14

1921 The Clinical Kinase Index: Prioritizing Understudied Kinases as Targets for the Treatment of Cancer

Essegian, D.; Khurana, R.; Stathias, V.; Schurer, S.

10.1101/2020.02.14.943886 — bioinformatics — Posted on 2020-02-14

1922 Differentiating the Roles of UL16, UL21 and Us3 in the Nuclear Egress of Herpes Simplex Virus Capsids

Gao, J.; Finnen, R. L.; Sherry, M. R.; Le Sage, V.; Banfield, B. W.

10.1101/2020.02.14.949750 — microbiology — Posted on 2020-02-14

1923 PhyRepID: a comparative phylogenomics approach for large-scale quantification of protein repeat evolution

van Belzen, I. A. E. M.; Deutekom, E. S.; Snel, B.

10.1101/2020.02.14.947036 — bioinformatics — Posted on 2020-02-14

1924 Antibiotics affect migratory restlessness orientation

Werber, Y.; Natan, E.; Vortman, Y.; Lavner, Y.

10.1101/2020.02.14.949651 — animal behavior and cognition — Posted on 2020-02-14

1925 Visual Attention Through Uncertainty Minimization in Recurrent Generative Models

Standvoss, K.; Quax, S. C.; van Gerven, M. A. J.

10.1101/2020.02.14.948992 — neuroscience — Posted on 2020-02-14

1926 Conditional Analysis Cakewalk

French, J. N.; Gaynor, B. J.; Perry, J. A.

10.1101/2020.02.14.947978 — bioinformatics — Posted on 2020-02-14

1927 Simultaneous human intracerebral stimulation and HD-EEG: ground-truth for source localization methods

Mikulan, E.; Russo, S.; Parmigiani, S.; Sarasso, S.; Zauli, F. M.; Rubino, A.; Avanzini, P.; Cattani, A.; Sorrentino, A.; Gibbs, S.; Cardinale, F.; Sartori, I.; Nobili, L.; Massimini, M.; Pigorini, A.

10.1101/2020.02.14.948984 — neuroscience — Posted on 2020-02-14

1928 TraCurate: efficiently curating cell tracks

Wagner, S.; Thierbach, K.; Zerjatke, T.; Glauche, I.; Roeder, I.; Scherf, N.

10.1101/2020.02.14.936740 — bioinformatics — Posted on 2020-02-14

1929 Temperature regulation as a tool to program synthetic microbial community composition

Lin, X. N.; Krieger, A. G.; Zhang, J.

10.1101/2020.02.14.944090 — systems biology — Posted on 2020-02-14

1930 βIII spectrin is required for orthogonal wiring between Purkinje cell dendrites and granule cell axons in the murine cerebellar circuit

Fujishima, K.; Kurisu, J.; Yamada, M.; Kengaku, M.

10.1101/2020.02.14.945188 — neuroscience — Posted on 2020-02-14

1931 Unstructured mRNAs form multivalent RNA-RNA interactions to generate TIS granule networks

Ma, W.; Zhen, G.; Xie, W.; Mayr, C.

10.1101/2020.02.14.949503 — molecular biology — Posted on 2020-02-14

1932 Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain

Pullen, M. Y.; Weihl, C. C.; True, H. L.

10.1101/2020.02.14.949792 — molecular biology — Posted on 2020-02-14

1933 TRM Integrins CD103 and CD49a Differentially Support Adherence and Motility After Resolution of Influenza Virus Infection

Reilly, E. C.; Lambert-Emo, K.; Buckley, P.; Reilly, N. S.; Chaves, F. A.; Yang, H.; Oakes, P. W.; Topham, D. J.

10.1101/2020.02.14.947986 — immunology — Posted on 2020-02-14

1934 A resurrection study reveals limited evolution of thermal performance in response to recent climate change across the geographic range of the scarlet monkeyflower

Wooliver, R.; Sheth, S. N.; Tittes, S. B.

10.1101/2020.02.14.934166 — evolutionary biology — Posted on 2020-02-14

1935 Conservation Genomic Analyses of African and Asiatic Cheetahs (Acinonyx jubatus) Across Their Current and Historic Species Range.

Prost, S.; Machado, A. P.; Zumbroich, J.; Preier, L.; Mahtani-Williams, S.; Guschanski, K.; Brealey, J. C.; Fernandes, C.; Vercammen, P.; Godsall-Bottriell, L.; Bottriell, P.; Dalton, D. L.; Kotze, A.; Burger, P. A.

10.1101/2020.02.14.949081 — evolutionary biology — Posted on 2020-02-14

1936 Cytosine methylation dynamics during post-testicular sperm maturation in mammals

Galan, C.; Serra, R.; Sun, F.; Rinaldi, V.; Conine, C.; Rando, O.

10.1101/2020.02.14.949487 — developmental biology — Posted on 2020-02-14

1937 HIV-1-infected human macrophages, by secreting RANKL, contribute to enhanced osteoclastogenesis

Mascarau, R.; Bertrand, F.; Labrousse, A.; Gennero, I.; Poincloux, R.; Maridonneau-Parini, I.; Raynaud-Messina, B.; Verollet, C.

10.1101/2020.02.14.947614 — cell biology — Posted on 2020-02-14

1938 Abelson-induced phosphorylation of TACC3 modulates its interaction with microtubules and affects its impact on axon outgrowth and guidance

Erdogan, B.; St. Clair, R.; Cammarata, G.; Zaccaro, T.; Ballif, B.; Lowery, L.

10.1101/2020.02.14.948448 — cell biology — Posted on 2020-02-14

1939 Bifurcation analysis of an impulsive system describing a Partial Nitritation and Anammox in a hybrid reactor

Wade, M. J.; Wolkowicz, G. S. K.

10.1101/2020.02.14.949099 — bioengineering — Posted on 2020-02-14

1940 A novel function of sphingosine kinase 2 in the metabolism of sphinga-4,14-diene lipids.

Couttas, T. A.; Rustam, Y. H.; Song, H.; Qi, Y.; Teo, J. D.; Chen, J.; Reid, G. E.; Don, A. S.

10.1101/2020.02.14.949974 — biochemistry — Posted on 2020-02-14

1941 Coordination between E. coli Cell Size and Cell Cycle Mediated by DnaA

Zhang, Q.; Zhang, Z.; Shi, H.

10.1101/2020.02.14.949446 — biophysics — Posted on 2020-02-14

1942 The prospective sense of agency is rooted in local and global properties of intrinsic functional brain networks

Di Plinio, S.; Perrucci, M. G.; Ebisch, S. J. H.

10.1101/2020.02.14.948885 — neuroscience — Posted on 2020-02-14

1943 Toward a comprehensive understanding of EEG and its analyses

Rocha, A. F.

10.1101/2020.02.14.948968 — neuroscience — Posted on 2020-02-14

1944 Activation of WNT signaling restores the facial deficits in a zebrafish with defects in cholesterol metabolism.

Castro, V. L.; Reyes-Nava, N. G.; Sanchez, B.; Gonzalez, C. G.; Quintana, A. M.

10.1101/2020.02.14.949958 — developmental biology — Posted on 2020-02-14

1945 ATRIP protects progenitor cells against DNA damage in vivo

Matos-Rodrigues, G. E.; Grigaravicius, P.; Lopez, B. S.; Hofmann, T.; Frappart, P.-O.; Martins, R. A. P.

10.1101/2020.02.14.948265 — cell biology — Posted on 2020-02-14

1946 Optimum Threshold Minimizes Noise in Timing of Intracellular Events

Kannoly, S.; Gao, T.; Dey, S.; Wang, I.-N.; Singh, A.; Dennehy, J. J.

10.1101/2020.02.14.949891 — biophysics — Posted on 2020-02-14

1947 Unified methods for feature selection in large-scale genomics data with censored survival outcomes

Spirko-Burns, L.; Devarajan, K.

10.1101/2020.02.14.944314 — bioinformatics — Posted on 2020-02-14

1948 A one-tube method for rapid and reliable plant genomic DNA isolation for PCR analysis

Hu, W.; Lagarias, J. C.

10.1101/2020.02.13.948455 — plant biology — Posted on 2020-02-14

1949 Autophagic degradation of the Cucumber mosaic virus virulence factor 2b balances antiviral RNA silencing with proviral plant fitness and virus seed transmission

Shukla, A.; Hoffmann, G.; Lopez-Gonzalez, S.; Hofius, D.; Hafren, A.

10.1101/2020.02.13.938316 — plant biology — Posted on 2020-02-14

1950 Long-term single-cell imaging and simulations of microtubules reveal driving forces for wall pattering during proto-xylem development

Schneider, R.; van't Klooster, K.; Picard, K.; van der Gucht, J.; Demura, T.; Janson, M.; Sampathkumar, A.; Deinum, E.; Keetlaar, T.; Persson, S.

10.1101/2020.02.13.938258 — plant biology — Posted on 2020-02-14

1951 Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy

Madar, A. D.; Pfammatter, J. A.; Bordenave, J.; Plumley, E. I.; Ravi, S.; Cowie, M.; Wallace, E. P.; Hermann, B. P. D.; Maganti, R. K.; Jones, M. V.

10.1101/2020.02.13.948364 — neuroscience — Posted on 2020-02-14

1952 Chronic wireless streaming of invasive neural recordings at home for circuit discovery and adaptive stimulation

Gilron, R.; Little, S.; Perrone, R.; Wilt, R.; de Hemptinne, C.; Yaroshinsky, M. S.; Racine, C. A.; Wang, S.; Ostrem, J. L.; Larson, P. S.; Wang, D. D.; Galifianakis, N. B.; Bledsoe, I.; San Luciano, M.; Dawes, H. E.; Worrell, G. A.; Kremen, V.; Borton, D.; Denison, T.; Starr, P. A.

10.1101/2020.02.13.948349 — neuroscience — Posted on 2020-02-14

1953 Slow wave-spindle coupling during sleep predicts language learning and associated oscillatory activity

Cross, Z. R.; Helfrich, R. F.; Kohler, M. J.; Corcoran, A. W.; Coussens, S.; Zou-Williams, L.; Schlesewsky, M.; Gaskell, M. G.; Knight, R. T.; Bornkessel-Schlesewsky, I.

10.1101/2020.02.13.948539 — neuroscience — Posted on 2020-02-14

1954 Fluid and crystallised intelligence are associated with distinct regionalisation patterns of cortical morphology

Palmer, C. E.; Zhao, W.; Loughnan, R. J.; Fan, C.-C.; Thompson, W. K.; Dale, A. M.; Jernigan, T. L.

10.1101/2020.02.13.948596 — neuroscience — Posted on 2020-02-14

1955 Motor training strengthens corticospinal suppression during movement preparation

Vassiliadis, P.; Derosiere, G.; Grandjean, J.; Duque, J.

10.1101/2020.02.14.948877 — neuroscience — Posted on 2020-02-14

1956 Opposite effects of choice history and stimulus history resolve a paradox of sequential choice bias

Bosch, E.; Fritsche, M.; Ehinger, B. V.; de Lange, F. P.

10.1101/2020.02.14.948919 — neuroscience — Posted on 2020-02-14

1957 THE HOK/SOK TOXIN/ANTITOXIN LOCUS ENHANCES BACTERIAL SUSCEPTIBILITY TO DOXYCYCLINE

Chukwudi, C. U.; Good, L.

10.1101/2020.02.13.948752 — molecular biology — Posted on 2020-02-14

1958 A new member in the Argonaute crew: the mt-miRNAs

Pozzi, A.; Dowling, D. K.

10.1101/2020.02.13.948554 — molecular biology — Posted on 2020-02-14

1959 Calcium homeostasis plays important roles in the internalisation and activities of the small synthetic antifungal peptide PAF26

Alexander, A. J.; Munoz, A.; Marcos, J. F.; Read, N. D.

10.1101/2020.02.14.948786 — molecular biology — Posted on 2020-02-14

1960 CCR5 deficiency impairs CD4+ T cell memory responses and antigenic sensitivity through increased ceramide synthesis

Martin, A.; Blanco, R.; Casas, J.; Saez, M. E.; Rodriguez-Bovolenta, E.; de Rojas, I. E.; Drechsler, C.; Real, L. M.; Fabrias, G.; Ruiz, A.; Castro, M.; Schamel, W. W. A.; Alarcon, B.; van Santen, H. M.; Manes, S.

10.1101/2020.02.14.948893 — immunology — Posted on 2020-02-14

1961 Resolving a QTL complex for height, heading, and grain yield on chromosome 3A in bread wheat

Martinez, A. F.; Lister, C.; Freeman, S.; Ma, J.; Berry, S.; Wingen, L.; Griffiths, S.

10.1101/2020.02.14.947846 — genetics — Posted on 2020-02-14

1962 Neonatal levels of acute phase proteins and risk of autism spectrum disorders

Gardner, R. M.; Lee, B. K.; Brynge, M.; Sjoqvist, H.; Dalman, C.; Karlsson, H.

10.1101/2020.02.13.947572 — molecular biology — Posted on 2020-02-14

1963 Maternal antibodies to gliadin and autism spectrum disorders in offspring - A population-based case-control study in Sweden

Gardner, R. M.; Samuelsson, I.; Severance, E. G.; Sjoqvist, H.; Yolken, R. H.; Dalman, C.; Karlsson, H.

10.1101/2020.02.13.948620 — molecular biology — Posted on 2020-02-14

1964 CGGBP1-regulated cytosine methylation at CTCF-binding motifs resists stochasticity

Patel, M.; Patel, D.; Datta, S.; Singh, U.

10.1101/2020.02.13.948604 — genomics — Posted on 2020-02-14

1965 Expression quantitative trait methylation analysis reveals methylomic associations with gene expression in childhood asthma

Kim, S.; Forno, E.; Zhang, R.; Yan, Q.; Boutaoui, N.; Acosta-Perez, E.; Canino, G.; Chen, W.; Celedon, J. C.

10.1101/2020.02.13.937391 — genomics — Posted on 2020-02-14

1966 Quantifying microbially mediated fitness differences reveals the tendency for plant-soil feedbacks to drive species exclusion among California annual plants

Kandlikar, G.; Yan, X.; Levine, J. M.; Kraft, N. J. B.

10.1101/2020.02.13.948679 — ecology — Posted on 2020-02-14

1967 Reconstruction of cell spatial organization based on ligand-receptor mediated self-assembly

Ren, X.; Zhong, G.; Zhang, Q.; Zhang, L.; sun, y.; Zhang, Z.

10.1101/2020.02.13.948521 — bioinformatics — Posted on 2020-02-14

1968 Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency

Perdue, L. A.; Do, P.; David, C.; Chyong, A.; Kellner, A.; Ruggieri, A.; Kim, H. R.; Salaita, K.; Lesinski, G. B.; Porter, C. C.; Dreaden, E. C.

10.1101/2020.02.13.948240 — bioengineering — Posted on 2020-02-14

1969 Comparison of the two up-to-date sequencing technologies for genome assembly: HiFi reads of Pacbio Sequel II system and ultralong reads of Oxford Nanopore

Lang, D.; Zhang, S.; Ren, P.; Liang, F.; Sun, Z.; Meng, G.; Tan, Y.; Hu, J.; Li, X.; Lai, Q.; Han, L.; Wang, D.; Hu, F.; Wang, W.; Liu, S.

10.1101/2020.02.13.948489 — genomics — Posted on 2020-02-14

1970 Phenotypic associations among cell cycle genes in Saccharomyces cerevisiae

Bermudez-Cruz, M.; Wu, P. I.; Callerame, D.; Hammer, S.; Hu, J. C.; Polymenis, M.

10.1101/2020.02.13.948257 — genetics — Posted on 2020-02-14

1971 Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration

Yang, L.; Liang, J.; Lam, S. M.; Yavuz, A.; Wang, M. C.; Shui, G.; Ding, M.; Huang, X.

10.1101/2020.02.13.948430 — cell biology — Posted on 2020-02-14

1972 Bile acid supplementation improves murine pancreatitis in association with the gut microbiota

Wan, Y.-D.; Zhu, R.-X.; Pan, X.-T.; Sun, T.-W.

10.1101/2020.02.13.948547 — bioinformatics — Posted on 2020-02-14

1973 Environmental Exposures Influence Nasal Microbiome Composition in a Longitudinal Study of Division I Collegiate Athletes

Kask, O.; Kyman, S.; Conn, K. A.; Gormley, J.; Gardner, J.; Johns, R. A.; Caporaso, J. G.; Bycura, D.; Sutliffe, J. T.; Cope, E. K.

10.1101/2020.02.13.946475 — microbiology — Posted on 2020-02-14

1974 Exposure to Mites Sensitizes Intestinal Stem Cell Maintenance, Splenic Marginal Zone B Cell Homeostasis, And Heart Development to Notch Dosage and Cooperativity.

Kobia, F. M.; Preusse, K.; Dai, Q.; Weaver, N.; Stein, S. J.; Pear, W.; Yuan, Z.; Kovall, R.; Kuang, Y.; Eafergen, N.; Sprinzak, D.; Gebelein, B.; Brunskill, E. W.; Kopan, R.

10.1101/2020.02.13.948224 — developmental biology — Posted on 2020-02-14

1975 β-catenin-Mediated Wnt Signal Transduction Proceeds Through an Endocytosis-Independent Mechanism

Rim, E. Y.; Kinney, L. K.; Nusse, R.

10.1101/2020.02.13.948380 — cell biology — Posted on 2020-02-14

1976 Machine Learning Algorithms for Predicting Coronary Artery Disease: Efforts Toward an Open Source Solution

Akella, A. B.; Kaushik, V.

10.1101/2020.02.13.948414 — bioinformatics — Posted on 2020-02-14

1977 Increased metal tolerance and bioaccumulation of zinc and cadmium in Chlamydomonas reinhardtii expressing a AtHMA4 C-terminal domain protein

Ibuot, A.; Webster, R. E.; Williams, L. E.; Pittman, J. K.

10.1101/2020.02.13.948307 — plant biology — Posted on 2020-02-14

1978 Pharmacologic activation of the mitochondrial phosphoenolpyruvate cycleenhances islet function in vivo

Abulizi, A.; Stark, R.; Cardone, R. L.; Lewandowski, S. L.; Zhao, X.; Alves, T. C.; Thomas, C.; Kung, C.; Wang, B.; Siebel, S.; Andrews, Z. B.; Merrins, M. J.; Kibbey, R. G.

10.1101/2020.02.13.947630 — physiology — Posted on 2020-02-14

1979 Cognitive performance in children and adolescents at high-risk for obsessive-compulsive disorder

Bernardes, E. T.; Cappi, C.; Souza, M. d. M. e.; Hoexter, M. Q.; Chacon, P.; Requena, G.; Miguel, E. C.; Shavitt, R. G.; Polanczyk, G. V.; Batistuzzo, M. C.

10.1101/2020.02.13.946061 — neuroscience — Posted on 2020-02-14

1980 Abstract neural representations of category membership beyond information coding stimulus or response

Mok, R. M.; Love, B. C.

10.1101/2020.02.13.947341 — neuroscience — Posted on 2020-02-14

1981 Dopaminergic modulation of human inter-temporal choice: a diffusion model analysis using the D2-receptor-antagonist haloperidol.

Wagner, B. J.; Clos, M.; Sommer, T.; Peters, J.

10.1101/2020.02.13.942383 — neuroscience — Posted on 2020-02-14

1982 Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson's disease

Guhathakurta, S.; Kim, J.; Basu, S.; Adler, E.; Je, G.; Fiadeiro, M. B.; Kim, Y.-S.

10.1101/2020.02.13.947465 — neuroscience — Posted on 2020-02-14

1983 Large Freshwater Phages with the Potential to Augment Aerobic Methane Oxidation

Chen, L.-X.; Meheust, R.; Crits-Christoph, A.; McMahon, K. D.; Colenbrander Nelson, T.; Warren, L. A.; Banfield, J.

10.1101/2020.02.13.942896 — microbiology — Posted on 2020-02-14

1984 STAT1-dependent tolerance of intestinal viral infection

Filyk, H. A.; Sharon, A. J.; Fonseca, N. M.; Simister, R. L.; Yuen, W.; Hardman, B. K.; Robinson, H. G.; Seo, J. H.; Rocha-Pereira, J.; Welch, I.; Neyts, J.; Crowe, S. A.; Osborne, L. C.

10.1101/2020.02.13.936252 — immunology — Posted on 2020-02-14

1985 A GT-seq panel for walleye (Sander vitreus) provides a generalized workflow for efficient development and implementation of amplicon panels in non-model organisms.

Bootsma, M.; Gruenthal, K. M.; McKinney, G. J.; Simmons, L.; Miller, L.; Sass, G. G.; Larson, W. A.

10.1101/2020.02.13.948331 — genomics — Posted on 2020-02-14

1986 Co-expression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders

Pang, K.; Wang, L.; Wang, W.; Zhou, J.; Cheng, C.; Han, K.; Zoghbi, H. Y.; Liu, Z.

10.1101/2020.02.13.948315 — genetics — Posted on 2020-02-14

1987 Structural genomics and interactomics of 2019 Wuhan novel coronavirus, 2019-nCoV, indicate evolutionary conserved functional regions of viral proteins

Cui, H.; Gao, Z.; Liu, M.; Lu, S.; Mkandawire, W.; Mo, S.; Narykov, O.; Srinivasan, S.; Korkin, D.

10.1101/2020.02.10.942136 — bioinformatics — Posted on 2020-02-14

1988 A Critical Role for Perivascular Cells in Amplifying Viral Haemorrhage Induced by Dengue Virus Non-Structural Protein 1

Cheung, Y. P.; Mastrullo, V.; Maselli, D.; Butsabong, T.; Madeddu, P.; Maringer, K.; Campagnolo, P.

10.1101/2020.02.13.948208 — microbiology — Posted on 2020-02-14

1989 β-L-1- Uracil (L-BHDU) Inhibits Varicella Zoster Virus Replication by Depleting the Cellular dTTP Pool

De, C.; Liu, D.; Singh, U. S.; Chu, C. K.; Moffat, J. F.

10.1101/2020.02.13.948216 — microbiology — Posted on 2020-02-14

1990 β-L-1- uracil (L-BHDU) effectiveness against varicella-zoster virus and herpes simplex virus type 1 depends on thymidine kinase activity

De, C.; Liu, D.; Depledge, D.; Breuer, J.; Singh, U. S.; Hartline, C.; Prichard, M.; Chu, C. K.; Moffat, J. F.

10.1101/2020.02.13.948190 — microbiology — Posted on 2020-02-14

1991 G4C2 repeat RNA mediates the disassembly of the nuclear pore complex in C9orf72 ALS/FTD

Rothstein, J. D.; Coyne, A. N.; Hayes, L.; Zaepfel, B. L.; Fitchman, B.; Salzberg, Y.; Bowen, K.; Trost, H.; Rigo, F.; Harel, A.; Svendsen, C. N.; Sareen, D.

10.1101/2020.02.13.947721 — neuroscience — Posted on 2020-02-14

1992 Bacterial deamination of residual levodopa medication for Parkinson's disease elicits inhibitory effect on gut motility

van Kessel, S. P.; de Jong, H. R.; Winkel, S. L.; van Leeuwen, S. S.; Nelemans, S. A.; Permentier, H.; Keshavarzian, A.; El Aidy, S.

10.1101/2020.02.13.945717 — microbiology — Posted on 2020-02-14

1993 Gut microbial genes are associated with neurocognition and brain development in healthy children

Bonham, K. S.; Bruchhage, M. M. K.; Rowland, S.; Volpe, L.; Dyer, K.; RESONANCE Consortium, ; D'Sa, V.; Huttenhower, C.; Deoni, S.; Klepac-Ceraj, V.

10.1101/2020.02.13.944181 — microbiology — Posted on 2020-02-14

1994 Structure-based identification and functional characterization of an essential lipocalin in the malaria parasite Plasmodium falciparum

Burda, P.-C.; Crosskey, T.; Lauk, K.; Zurborg, A.; Söhnchen, C.; Liffner, B.; Wilcke, L.; Strauss, J.; Jeffries, C.; Svergun, D. I.; Wilson, D. W.; Wilmanns, M.; Gilberger, T.-W.

10.1101/2020.02.13.947507 — cell biology — Posted on 2020-02-14

1995 The RNA binding protein hnRNP-U is required for physiological hypertrophy of skeletal muscle

Bagchi, D.; Mason, B. D.; Baldino, K.; Li, B.; Lee, E.-J.; Zhang, Y.; Chu, L. K.; El Raheb, S.; Sinha, I.; Neppl, R. L.

10.1101/2020.02.13.944298 — cell biology — Posted on 2020-02-14

1996 mzMLb: a future-proof raw mass spectrometry data format based on standards-compliant mzML and optimized for speed and storage requirements

Bhamber, R. S.; Jankevics, A.; Deutsch, E. W.; Jones, A. R.; Dowsey, A. W.

10.1101/2020.02.13.947218 — bioinformatics — Posted on 2020-02-14

1997 Hypercapnia Suppresses Macrophage Antiviral Activity and Increases Mortality of Influenza A 1 Infection via Akt1

Casalino-Matsuda, S. M.; Chen, F.; Gonzalez-Gonzalez, F. J.; Nair, A.; Dib, S.; Yemelyanov, A.; Gates, K. L.; Budinger, G. R. S.; Beitel, G.; Sporn, P. H. S.

10.1101/2020.02.13.946400 — immunology — Posted on 2020-02-14

1998 Amphibians in the Brazilian Cerrado: diversity, research effort and conservation

Alves, E. G.

10.1101/2020.02.13.945618 — ecology — Posted on 2020-02-14

1999 Revisiting the links-species scaling relationship in food webs

MacDonald, A. M.; Banville, F.; Poisot, T.

10.1101/2020.02.13.947531 — ecology — Posted on 2020-02-14

2000 Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin

Aparicio, G.; Rodao, M.; Badano, J. L.; Zolessi, F. R.

10.1101/2020.02.13.947663 — developmental biology — Posted on 2020-02-14

2001 Enhanced information processing at revisited fixation locations

Nikolaev, A. R.; Giannini, M.; Meghanathan, R. N.; van Leeuwen, C.

10.1101/660308 — neuroscience — Posted on 2020-02-14

2002 Comparison of protein and peptide fractionation approaches in protein identification and quantification from Saccharomyces cerevisiae

Deng, L.; Handler, D. C. L.; Multari, D.; Haynes, P. A.

10.1101/2020.02.13.948513 — biochemistry — Posted on 2020-02-14

2003 Overexpression of sedoheptulose-1,7-bisphosphatase enhances photosynthesis in Chlamydomonas reinhardtii and has no effect on the abundance of other Calvin-Benson cycle enzymes

Hammel, A.; Sommer, F.; Zimmer, D.; Stitt, M.; Muhlhaus, T.; Schroda, M.

10.1101/2020.02.14.949040 — plant biology — Posted on 2020-02-14

2004 Separation of newly replicated bacterial chromosomes: the role of Escherichia coli Topoisomerase IV

Helgesen, E.; Saetre, F.; Skarstad, K.

10.1101/2020.02.14.948935 — molecular biology — Posted on 2020-02-14

2005 A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of Plasmodium berghei during gametogony and parasite transmission.

Balestra, A. C.; Zeeshan, M.; Rea, E.; Pasquarello, C.; Klages, N.; Mourier, T.; Subudhi, A. K.; Arboit, P.; Brusini, L. A.; Pandey, R.; Brady, D.; Vaughan, S.; Holder, A. A.; Pain, A.; Ferguson, D.; Hainard, A.; Tewari, R.; Brochet, M.

10.1101/2020.02.14.928432 — microbiology — Posted on 2020-02-14

2006 Microbiota-Independent Antiviral Effects of Antibiotics on Enteric Viruses

Woods Acevedo, M. A.; Pfeiffer, J. K.

10.1101/2020.02.14.949123 — microbiology — Posted on 2020-02-14

2007 Improved discrimination of asymmetric and symmetric arginine dimethylation by optimization of the normalized collision energy in LC-MS proteomics

Hartel, N. G.; Liu, C. Z.; Graham, N. A.

10.1101/2020.02.14.949255 — biochemistry — Posted on 2020-02-14

2008 The LRRC8A:C Heteromeric Channel Is a cGAMP Transporter and the Dominant cGAMP Importer in Human Vasculature Cells

Lahey, L. J.; Wen, X.; Mardjuki, R. E.; Böhnert, V.; Ritchie, C.; Carozza, J. A.; Hess, G. T.; Maduke, M.; Bassik, M. C.; Li, L.

10.1101/2020.02.13.948273 — biochemistry — Posted on 2020-02-14

2009 Early neurulation recapitulated in assemblies of embryonic and extraembryonic cells

Berenger-Currias, N. M. L. P.; Mircea, M.; Adegeest, E.; van den Berg, P. R.; Feliksik, M.; Hochane, M.; Idema, T.; Tans, S.; Semrau, S.

10.1101/2020.02.13.947655 — developmental biology — Posted on 2020-02-14

2010 Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site.

Smith, S. J.; Towers, N.; Demetriou, K.; Mohun, T. J.

10.1101/2020.02.13.947424 — developmental biology — Posted on 2020-02-14

2011 Factors affecting Response to Recurrent Genomic Selection in Soybeans

Ramasubramanian, V.; Beavis, W. D.

10.1101/2020.02.14.949008 — genetics — Posted on 2020-02-14

2012 Relative efficiencies of simple and complex substitution models in estimating divergence times in phylogenomics

Tao, Q.; Barba-Montoya, J.; Huuki, L. A.; Durnan, M. K.; Kumar, S.

10.1101/2020.02.14.949339 — evolutionary biology — Posted on 2020-02-14

2013 In situ structural analysis of the flagellum attachment zone in Trypanosoma brucei using cryo-scanning transmission electron tomography

Trepout, S.

10.1101/2020.02.14.949115 — cell biology — Posted on 2020-02-14

2014 Mitochondrial CaMKII causes metabolic reprogramming, energetic insufficiency, and dilated cardiomyopathy

Luczak, E. D.; Wu, Y.; Granger, J. M.; Joiner, M.-l. A.; Wilson, N. R.; Gupta, A.; Umapathi, P.; Murphy, K. R.; Reyes Gaido, O. E.; Sabet, A.; Corradini, E.; Wang, Y.; Heck, A. J.; Wei, A.-C.; Weiss, R. G.; Anderson, M. E.

10.1101/2020.02.13.947564 — molecular biology — Posted on 2020-02-14

2015 Causal dynamical modelling predicts novel regulatory genes of FOXP3 in human regulatory T cells

Sawlekar, R.; Magni, S.; Capelle, C.; Baron, A.; Zeng, N.; Mombaerts, L.; Yue, Z.; Yuan, Y.; He, F. Q.; Goncalves, J.

10.1101/2020.02.13.943688 — systems biology — Posted on 2020-02-14

2016 Global Dynamic Molecular Profiles of Stomatal Lineage Cell Development by Single-Cell RNA Sequencing

Liu, Z.; Zhou, Y.; Guo, J.; Li, J.; Tian, Z.; Zhu, Z.; Wang, J.; Wu, R.; Zhang, B.; Hu, Y.; Sun, Y.; Shangguan, Y.; Li, W.; Li, T.; Hu, Y.; Guo, C.; Rochaix, J.-D.; Miao, Y.; Sun, X.

10.1101/2020.02.13.947549 — plant biology — Posted on 2020-02-14

2017 Drug-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting

Michaelis, M.; Wass, M. N.; Reddin, I.; Voges, Y.; Rothweiler, F.; Hehlgans, S.; Cinatl, J.; Mernberger, M.; Nist, A.; Stiewe, T.; Roedel, F.; Cinatl, J.

10.1101/2020.02.13.947374 — pharmacology and toxicology — Posted on 2020-02-14

2018 When vision lags, motor prediction follows

Rohde, M.; Altan, G.; Ernst, M. O.

10.1101/2020.02.13.937235 — neuroscience — Posted on 2020-02-14

2019 Prior expectations evoke stimulus templates in the deep layers of V1

Aitken, F.; Menelaou, G.; Warrington, O.; Koolschijn, R. S.; Corbin, N.; Callaghan, M. F.; Kok, P.

10.1101/2020.02.13.947622 — neuroscience — Posted on 2020-02-14

2020 Effects of MP2RAGE B1+ sensitivity on inter-site T1 reproducibility and morphometry at 7T

Haast, R. A.; Lau, J. C.; Ivanov, D.; Menon, R. S.; Uludag, K.; Khan, A. R.

10.1101/2020.02.13.947382 — neuroscience — Posted on 2020-02-14

2021 Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator

Bergstrom, E. N.; Barnes, M.; Martincorena, I.; Alexandrov, L. B.

10.1101/2020.02.13.948422 — genomics — Posted on 2020-02-14

2022 Rice Bran and Quercetin Produce a Positive Synergistic Effect on Human Gut Microbiota, Elevate the Level of Propionate, and Reduce the Population of Enterobacteriaceae family when Determined using a Bioreactor Model.

Ghimire, S.; Wongkuna, S.; Sankaranarayanan, R.; Ryan, E. P.; Bhat, G. J.; Scaria, J.

10.1101/2020.02.13.947515 — microbiology — Posted on 2020-02-14

2023 seagull: lasso, group lasso and sparse-group lasso regularisation for linear regression models via proximal gradient descent

Klosa, J.; Simon, N.; Westermark, P. O.; Liebscher, V.; Wittenburg, D.

10.1101/2020.02.13.947473 — bioinformatics — Posted on 2020-02-14

2024 Endocrine fine-tuning of daily locomotor activity patterns under non-starving conditions in Drosophila

Pauls, D.; Selcho, M.; Raederscheidt, J.; Amatobi, K.; Fekete, A.; Krischke, M.; Hermann-Luibl, C.; Helfrich-Foerster, C.; Kuehnlein, R. P.; Mueller, M. J.; Wegener, C.

10.1101/2020.02.13.947556 — neuroscience — Posted on 2020-02-14

2025 Inhibitory CD200-receptor signaling is rewired by type I interferon

van der Vlist, M.; Pascoal Ramos, M. I.; van den Hoogen, L. L.; Hiddingh, S.; Timmerman, L.; de Hond, T. A. P.; Kaan, E. D.; van der Kroef, M.; Lebbink, R. J.; Peters, F. M. A.; Khoury-Hanold, W.; Fritsch-Stork, R.; Radstake, T.; Meyaard, L.

10.1101/2020.02.06.933739 — immunology — Posted on 2020-02-14

2026 Identification of potential candidates for drug designing against Klebsiella Pneumoniae among hypothetical proteins of DNA Adenine Methyltransferase through subtractive genomics approach

Kumar, S.; Mohd Omeershffudin, U. N.

10.1101/2020.02.13.947101 — bioinformatics — Posted on 2020-02-14

2027 Machine Boss: Rapid Prototyping of Bioinformatic Automata

Silvestre-Ryan, J.; Wang, Y.; Sharma, M.; Lin, S.; Shen, Y.; Dider, S.; Holmes, I.

10.1101/2020.02.13.945071 — bioinformatics — Posted on 2020-02-14

2028 Altered parasitism of a butterfly assemblage associated with a range-expanding species

Audusseau, H.; Ryrholm, N.; Stefanescu, C.; Tharel, S.; Jansson, C.; Champeaux, L.; Shaw, M. R.; Raper, C.; Lewis, O.; Janz, N.; Schmucki, R.

10.1101/2020.02.13.947440 — ecology — Posted on 2020-02-14

2029 ROS-triggered AMPK de-SUMOylation promotes Warburg effect in hepatocellular carcinoma cells

Zhang, S.

10.1101/2020.02.13.947333 — cancer biology — Posted on 2020-02-14

2030 Single-cell ATAC-seq clustering and differential analysis by convolution-based approach

Lin, L.; Zhang, L.

10.1101/2020.02.13.947242 — bioinformatics — Posted on 2020-02-14

2031 Human hormone seasonality

Tendler, A.; Bar, A.; Mendelson Cohen, N.; Karin, O.; Korem Kohanim, Y.; Maimon, L.; Milo, T.; Raz, M.; Mayo, A.; Tanay, A.; Alon, U.

10.1101/2020.02.13.947366 — systems biology — Posted on 2020-02-14

2032 Validating the potential of double-stranded RNA targeting Colorado potato beetle mesh gene in laboratory and field trials

Petek, M.; Coll, A.; Ferenc, R.; Razinger, J.; Gruden, K.

10.1101/2020.02.13.945097 — plant biology — Posted on 2020-02-14

2033 Bacteria maintain Slightly Beneficial Genes and Selfish Genetic Elements through the evolution of Horizontal Gene Transfer

Dijk, B. v.; Hogeweg, P.; Doekes, H.; Takeuchi, N.

10.1101/2020.02.13.947077 — microbiology — Posted on 2020-02-14

2034 A universal subcuticular bacterial symbiont of a coral predator, the crown-of-thorns starfish

Wada, N.; Yuasa, H.; Kajitani, R.; Gotoh, Y.; Ogura, Y.; Yoshimura, D.; Toyoda, A.; Tang, S.-L.; Higashimura, Y.; Sweatman, H.; Forsman, Z. H.; Bronstein, O.; Eyal, G.; Thongtham, N.; Itoh, T.; Hayashi, T.; Yasuda, N.

10.1101/2020.02.13.947093 — microbiology — Posted on 2020-02-14

2035 Distinct chemotactic behavior in the original Escherichia coli K-12 depending on forward-and-backward swimming, not on run-tumble movements

Kinosita, Y.; Ishida, T.; Yoshida, M.; Ito, R.; Morimoto, Y. V.; Goto, K.; Berry, R. M.; Nishizaka, T.; Sowa, Y.

10.1101/2020.02.13.947150 — microbiology — Posted on 2020-02-14

2036 RootDigger: a root placement program for phylogenetic trees

Bettisworth, B.; Stamatakis, A.

10.1101/2020.02.13.935304 — bioinformatics — Posted on 2020-02-14

2037 LanD-like Flavoprotein-Catalyzed Aminovinyl-Cysteine Formation through Oxidative Decarboxylation and Cyclization of a Peptide at the C-Terminus

Liu, J.; Qiu, Y.; Fu, T.; Li, M.; Li, Y.; Yang, Q.; Tang, Z.; Tang, H.; Li, G.; Pan, L.; Liu, W.

10.1101/2020.02.13.947028 — biochemistry — Posted on 2020-02-14

2038 Reversal of β-amyloid induced microglial toxicity in vitro by activation of Fpr2/3

Wickstead, E. S.; Karim, H. A.; Manuel, R. E.; Biggs, C. S.; Getting, S. J.; McArthur, S.

10.1101/2020.02.13.947051 — neuroscience — Posted on 2020-02-14

2039 Efficient immune cell genome engineering with improved CRISPR editing tools

Chan, W.; Gottschalk, R. A.; Yao, Y.; Pomerantz, J.; Germain, R. N.

10.1101/2020.02.13.947002 — genomics — Posted on 2020-02-14

2040 Unisexual flower initiation in the monoecious Quercus suber L., a molecular approach

Sobral, R. S.; Silva, H. G.; Laranjeira, S. C. C.; Magalhaes, J.; Andrade, L.; Alhinho, A. T.; Costa, M. M. R.

10.1101/2020.02.13.945295 — plant biology — Posted on 2020-02-14

2041 Percolation in the resting zebrafish habenula

Suryadi, ; Cheng, R.-K.; Jesuthasan, S. J.; Chew, L. Y.

10.1101/481358 — neuroscience — Posted on 2020-02-14

2042 RecA mediated homology search finds segregated sister locus in minutes after a double stranded break

Gynna, A. H.; Wiktor, J.; Leroy, P.; Elf, J.

10.1101/2020.02.13.946996 — microbiology — Posted on 2020-02-14

2043 Reliable data collection in participatory trials to assess digital healthcare apps.

Park, J.; Park, S.; Kim, G.; Kim, K.; Jung, J.; Yoo, S.; Yi, G.-S.; Lee, D.

10.1101/2020.02.05.935049 — bioinformatics — Posted on 2020-02-14

2044 Integrative analyses to investigate the link between microbial activity and molecules degradation during anaerobic digestion

Cardona, L.; Le Cao, K.-A.; Puig-Castellvi, F.; Bureau, C.; Madigou, C.; Mazeas, L.; Chapleur, O.

10.1101/2020.02.13.946970 — bioengineering — Posted on 2020-02-14

2045 Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice

Chiao, Y. A.; Zhang, H.; Sweetwyne, M.; Whitson, J.; Ting, Y. S.; Basisty, N.; Pino, L.; Quarles, E.; Nguyen, N.-H.; Campbell, M.; Zhang, T.; Gaffrey, M. J.; Merrihew, G.; Wang, L.; Yue, Y.; Duan, D.; Granzier, H.; Szeto, H. H.; Qian, W.-J.; Marcinek, D.; MacCoss, M. J.; Rabinovitch, P. S.

10.1101/2020.01.02.893008 — physiology — Posted on 2020-02-14

2046 The semantic control network mediates the relationship between symbolic numerical order processing and arithmetic performance in children

Sommerauer, G.; Grass, K.-H.; Grabner, R.; Vogel, S.

10.1101/791012 — neuroscience — Posted on 2020-02-14

2047 New methods to calculate concordance factors for phylogenomic datasets

Minh, B. Q.; Hahn, M.; Lanfear, R.

10.1101/487801 — evolutionary biology — Posted on 2020-02-14

2048 The haemodynamics of the human placenta in utero

Dellschaft, N. S.; Hutchinson, G.; Shah, S.; Jones, N. W.; Bradley, C.; Leach, L.; Platt, C.; Bowtell, R.; Gowland, P.

10.1101/2020.02.07.938589 — physiology — Posted on 2020-02-14

2049 Kinetic control of stationary flux ratios for a wide range of biochemical processes

Mallory, J. D.; Kolomeisky, A.; Igoshin, O. A.

10.1101/858126 — biophysics — Posted on 2020-02-14

2050 Calcium-independent astrocytic lipid release modulates neuronal activity through Kv channels

Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.

10.1101/2020.01.12.903393 — neuroscience — Posted on 2020-02-14

2051 Divergent density feedback control of migratory predator recovery following sex-biased perturbations

Goto, D.; Hamel, M. J.; Hammen, J. J.; Rugg, M. L.; Pegg, M. A.; Forbes, V. E.

10.1101/828244 — ecology — Posted on 2020-02-14

2052 Poor availability of context-specific evidence hampers decision-making in conservation

Christie, A. P.; Amano, T.; Martin, P. A.; Petrovan, S. O.; Shackelford, G. E.; Simmons, B. I.; Smith, R. K.; Williams, D. R.; Wordley, C. F. R.; Sutherland, W. J.

10.1101/2020.02.13.946954 — ecology — Posted on 2020-02-14

2053 Human pluripotent stem cell modeling of tuberous sclerosis complex reveals lineage-specific therapeutic vulnerabilities

Delaney, S. P.; Julian, L. M.; Pietrobon, A.; Yockell-Lelievre, J.; Dore, C.; Wang, T. T.; Doyon, V. C.; Raymond, A.; Patten, D. A.; Kristof, A. S.; Harper, M.-E.; Sun, H.; Stanford, W. L.

10.1101/683359 — cancer biology — Posted on 2020-02-14

2054 Practical Speedup of Bayesian Inference of Species Phylogenies by Restricting the Space of Gene Trees

Wang, Y.; Ogilvie, H. A.; Nakhleh, L.

10.1101/770784 — bioinformatics — Posted on 2020-02-14

2055 Axonal gap junctions in the fly visual system enable fast prediction for evasive flight maneuvers

Wang, S.; Borst, A.; Segev, I.; Palmer, S.

10.1101/814319 — neuroscience — Posted on 2020-02-14

2056 Listeriolysin O promotes the intravacuolar growth of Listeria monocytogenes in epithelial cells

Peron Cane, C.; Leblanc, J.; Wingertsmann, L.; Fernandez, J.-C.; Gautier, A.; Desprat, N.; Lebreton, A.

10.1101/2019.12.23.886689 — microbiology — Posted on 2020-02-14

2057 Epistasis, inbreeding depression and the evolution of self-fertilization

Abu Awad, D.; Roze, D.

10.1101/809814 — evolutionary biology — Posted on 2020-02-14

2058 ShearFAST: a user-friendly in vitro toolset for high throughput, inexpensive fluid shear stress experiments.

Smith, T. B.; De Nunzio, A. M.; Patel, K.; Munford, H.; Alam, T.; Powell, O.; Heneghan, N.; Ready, A.; Nath, J.; Ludwig, C.

10.1101/2020.01.31.929513 — cell biology — Posted on 2020-02-14

2059 Hallmarks of frailty and osteosarcopenia in prematurely aged PolgAD257A/D257A mice

Scheuren, A. C.; D'Hulst, G.; Kuhn, G. A.; Masschelein, E.; Wehrle, E.; De Bock, K.; Müller, R.

10.1101/758243 — physiology — Posted on 2020-02-14

2060 Feasibility of spiral fMRI based on an LTI gradient model

Graedel, N. N.; Kasper, L.; Engel, M.; Nussbaum, J.; Wilm, B. J.; Pruessmann, K. P.; Vannesjo, S. J.

10.1101/805580 — neuroscience — Posted on 2020-02-14

2061 Closer to critical resting-state neural dynamics in individuals with higher fluid intelligence

Ezaki, T.; Reis, E. F. d.; Watanabe, T.; Sakaki, M.; Masuda, N.

10.1101/688655 — neuroscience — Posted on 2020-02-14

2062 Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to 1 CA1 by differential modulation of feedforward inhibitory circuits

Palacios-Filardo, J.; Udakis, M.; Brown, G. A.; Tehan, B. G.; Congreve, M. S.; Nathan, P. J.; Brown, A. J. H.; Mellor, J.

10.1101/2020.01.20.912873 — neuroscience — Posted on 2020-02-14

2063 Heritability of the Mouse Brain Connectome

Wang, N.; Anderson, R. J.; Ashbrook, D. G.; Gopalakrishnan, V.; Park, Y.; Priebe, C. E.; Qi, Y.; Vogelstein, J. T.; Williams, R. W.; Johnson, G. A.

10.1101/701755 — neuroscience — Posted on 2020-02-14

2064 Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development

Maccallini, P.; Bavasso, F.; Scatolini, L.; Bucciarelli, E.; Noviello, G.; Lisi, V.; Palumbo, V.; D'Angeli, S.; Cacchione, S.; Cenci, G.; Ciapponi, L.; Wakefield, J. G.; Gatti, M.; raffa, g. d.

10.1101/2020.02.06.936724 — genetics — Posted on 2020-02-14

2065 Recent fluctuations in Mexican American genomes have altered the genetic architecture of biomedical traits

Spear, M. L.; Diaz-Papkovich, A.; Ziv, E.; Yracheta, J. M.; Gravel, S.; Torgerson, D. G.; Hernandez, R.

10.1101/2020.01.13.905141 — genetics — Posted on 2020-02-14

2066 EXOSC10 sculpts the transcriptome during the growth-to-maturation transition in mouse oocytes

Wu, D.; Dean, J.

10.1101/663377 — developmental biology — Posted on 2020-02-14

2067 Effects of surfaces and macromolecular crowding on bimolecular reaction rates

Andrews, S. S.

10.1101/844753 — biophysics — Posted on 2020-02-14

2068 Modulation of host lipid membrane elasticity and dipole potential induced by bacterial membrane vesicles

Prince, A.; Tiwari, A.; Mandal, T.; Sharma, K.; Kanik, N.; Sinha, D. K.; Saleem, M.

10.1101/827519 — biophysics — Posted on 2020-02-14

2069 Hearing impairment is associated with enhanced neural tracking of the speech envelope

Decruy, L.; Vanthornhout, J.; Francart, T.

10.1101/815530 — neuroscience — Posted on 2020-02-14

2070 Interferons drive development of novel interleukin-15-responsive macrophages

Gordon, S. M.; Nishiguchi, M. A.; Chase, J. M.; Mani, S.; Mainigi, M. A.; Behrens, E. M.

10.1101/663476 — immunology — Posted on 2020-02-14

2071 Actin accumulates nesprin-2 at the front of the nucleus during confined cell migration

Davidson, P. M.; Battistella, A.; Dejardin, T.; Betz, T.; Plastino, J.; Cadot, B.; Borghi, N.; Sykes, C.

10.1101/713982 — cell biology — Posted on 2020-02-14

2072 Characterization of HIF-dependent alternative isoforms in pancreatic cancer

Markolin, P.; Davidson, N.; Hirt, C. K.; Chabbert, C.; Zamboni, N.; Schwank, G.; Raetsch, G.

10.1101/826156 — cell biology — Posted on 2020-02-14

2073 Automated Threshold Selection for Cryo-EM Density Maps

Pfab, J.; Si, D.

10.1101/657395 — bioinformatics — Posted on 2020-02-14

2074 A flexible anatomic set of mechanical models for the organ of Corti

Berger, J.; Rubinstein, J.

10.1101/760835 — systems biology — Posted on 2020-02-14

2075 I TRIED A BUNCH OF THINGS: THE DANGERS OF UNEXPECTED OVERFITTING IN CLASSIFICATION

Skocik, M.; Hosseini, M.; Collins, J.; Callahan-Flintoft, C.; Jones, W.; Bowman, H.; Wyble, B.

10.1101/078816 — neuroscience — Posted on 2020-02-14

2076 Disruption of the transcription factor NEUROD2 causes an autism syndrome via cell-autonomous defects in cortical projection neurons

Runge, K.; Mathieu, R.; Bugeon, S.; Lafi, S.; Beurrier, C.; Sahu, S.; Schaller, F.; Loubat, A.; Herault, L.; Gaillard, S.; Cahuc, M.; Pallesi-Pocachard, E.; Montheil, A.; Bosio, A.; Rosenfeld, J. A.; Hudson, E.; Lindstrom, K.; Mercimek-Andrews, S.; Jeffries, L.; Van Haeringen, A.; Vanakker, O.; Pichon, B.; Van Hecke, A.; Amrom, D.; Kury, S.; Gamble, C.; Represa, A.; Cardoso, C.; Cremer, H.; de Chevigny, A.

10.1101/296889 — neuroscience — Posted on 2020-02-14

2077 Dissociable effects of visual crowding on the perception of colour and motion

Greenwood, J. A.; Parsons, M. J.

10.1101/639450 — neuroscience — Posted on 2020-02-14

2078 Sensory learning and inference is impaired in the non-clinical continuum of psychosis: a replication study

Dzafic, I.; Randeniya, R.; Harris, C. D.; Bammel, M.; Garrido, M. I.

10.1101/296988 — neuroscience — Posted on 2020-02-14

2079 Cheaters shape the evolution of phenotypic heterogeneity in Bacillus subtilis biofilms

Martin, M.; Dragos, A.; Otto, S. B.; Schafer, D.; Brix, S.; Maroti, G.; Kovacs, A. T.

10.1101/494716 — microbiology — Posted on 2020-02-14

2080 Epiclomal: probabilistic clustering of sparse single-cell DNA methylation data

10.1101/414482 — genomics — Posted on 2020-02-14

2081 Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions

Schotanus, K.; Heitman, J.

10.1101/526962 — genetics — Posted on 2020-02-14

2082 Genetic architecture influences when and how hybridization contributes to colonization

Reatini, B.; Vision, T. J.

10.1101/705954 — evolutionary biology — Posted on 2020-02-14

2083 Cellular memory enhances bacterial chemotactic navigation in rugged environments

Gosztolai, A.; Barahona, M.

10.1101/733345 — biophysics — Posted on 2020-02-14

2084 De novo protein design enables precise induction of functional antibodies in vivo

Sesterhenn, F.; Yang, C.; Cramer, J.; Bonet, J.; Wen, X.; Abriata, L.; Kucharska, I.; Chiang, C.-I.; Wang, Y.; Castoro, G.; Vollers, S.; Galloux, M.; Charles-Adrien, R.; Dheilly, E.; Rosset, S.; Corthesy, P.; Georgeon, S.; Villard, M.; Descamps, D.; Oricchio, E.; Rameix-Welti, M.-A.; Mas, V.; Ervin, S.; Eleouet, J.-f.; Riffault, S.; Bates, J.; Julien, J.-P.; Li, Y.; Jardetzky, T. S.; Krey, T.; Correia, B.

10.1101/685867 — bioengineering — Posted on 2020-02-14

2085 Diffusion MRI reveals in vivo and non-invasively changes in astrocyte function induced by an aquaporin-4 inhibitor.

Debacker, C.; Djemai, B.; Tsurugizawa, T.; Ciobanu, L.; Le Bihan, D.

10.1101/2020.02.13.947291 — neuroscience — Posted on 2020-02-13

2086 Gut carriage of antimicrobial resistance genes in women exposed to small-scale poultry farms in rural Uganda: a feasibility study

Weil, A. A.; Debela, M. D.; Muyanja, D.; Kakuhikire, B.; Baguma, C.; Bangsberg, D.; Tsai, A. C.; Lai, P. S.

10.1101/2020.02.13.947226 — microbiology — Posted on 2020-02-13

2087 Gene expression noise can promote the fixation of beneficial mutations in fluctuating environments

Schmutzer, M.; Wagner, A.

10.1101/2020.02.13.947275 — evolutionary biology — Posted on 2020-02-13

2088 Exploring spatiotemporal changes in ecosystem service values and hotspots in Southwest of China, Mekong Region

Zhang, Z.; Yang, J.; Yang, X.; Xie, F.; Junjie Yang, Xin Yang,Fuming Xie,

10.1101/2020.02.13.947317 — ecology — Posted on 2020-02-13

2089 Long-term changes in kelp forests in an inner basin of the Salish Sea

Berry, H. D.; Mumford, T. F.; Christiaen, B.; Dowty, P.; Calloway, M.; Ferrier, L.; Grossman, E. E.; VanArendonk, N. R.

10.1101/2020.02.13.947309 — ecology — Posted on 2020-02-13

2090 Democratizing water monitoring: Implementation of a community-based qPCR monitoring program for recreational water hazards.

Rudko, S. P.; Reimink, R. R.; Peter, B.; White, J.; Hanington, P. C.

10.1101/2020.02.13.947259 — scientific communication and education — Posted on 2020-02-13

2091 Interspike intervals within retinal spike bursts combinatorially encode multiple stimulus features

Ishii, T.; Hosoya, T.

10.1101/2020.02.13.947283 — neuroscience — Posted on 2020-02-13

2092 Cell-specific cargo delivery using synthetic bacterial spores

Kong, M.; Updegrove, T. B.; Constantino, M. A.; Gallardo, D.; Wu, I.-L.; Fitzgerald, D.; Tanner, K.; Ramamurthi, K. S.

10.1101/2020.02.13.947606 — synthetic biology — Posted on 2020-02-13

2093 Golgi-localized exo-β1,3-galactosidases involved in AGP modification and root cell expansion in Arabidopsis

Nibbering, P.; Petersen, B.; Motawia, M. S.; Jorgensen, B.; Ulvskov, P.; Niittyla, T.

10.1101/2020.02.13.947820 — plant biology — Posted on 2020-02-13

2094 High temporal resolution reveals simultaneous plasma membrane recruitment of the TPLATE complex subunits.

Wang, J.; Mylle, E.; Johnson, A.; Besbrugge, N.; De Jaeger, G.; Friml, J.; Pleskot, R.; Van Damme, D.

10.1101/2020.02.13.948109 — cell biology — Posted on 2020-02-13

2095 Stress-Dependent Conformational Changes of Artemin: Effects of Heat and Oxidant

Takalloo, Z.; Afshar Ardakani, Z.; Maroufi, B.; Shahangian, S. S.; H. Sajedi, R.

10.1101/2020.02.12.946236 — biochemistry — Posted on 2020-02-13

2096 Co-expression analysis is biased by a mean-correlation relationship

Wang, Y.; Hicks, S. C.; Hansen, K. D.

10.1101/2020.02.13.944777 — genomics — Posted on 2020-02-13

2097 MSH1 is required for maintenance of the low mutation rates in plant mitochondrial and plastid genomes

Wu, Z.; Waneka, G.; Broz, A. K.; King, C. R.; Sloan, D. B.

10.1101/2020.02.13.947598 — genetics — Posted on 2020-02-13

2098 Selective Germline Genome Edited Pig Meninges Grafts for the Abdominal Wall Closure in Damage Control Surgery

zou, l.; zhang, y.; He, y.; Yu, H.; chen, j.; liu, d.; Lin, S.; gao, m.; zhong, g.; lei, w.; zhou, g.; zou, x.; li, K.; yu, y.; zha, g.; li, l.; zeng, y.; wang, j.; Wang, G.

10.1101/2020.02.12.946178 — synthetic biology — Posted on 2020-02-13

2099 Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

Wu, C.; Ranjan, A.; Nguyen, V. Q.; Liu, S.; Wisniewski, J.; Kim, J. M.; Tang, X.; Mizuguchi, G.; Elalaoui, E.; Jou, V.; Nickels, T. J.; English, B. P.; Zheng, Q.; Luk, E.; Lavis, L. D.; Lionnet, T.

10.1101/2020.02.13.947119 — molecular biology — Posted on 2020-02-13

2100 Hiding in plain sight: structure and sequence analysis reveals the importance of the antibody DE loop for antibody-antigen binding.

Kelow, S. P.; Adolf-Bryfogle, J.; Dunbrack, R.

10.1101/2020.02.12.946350 — bioinformatics — Posted on 2020-02-13

2101 Composition of the Lipid Droplets of the Bovine Corpus Luteum

Talbott, H. A.; Plewes, M. R.; Krause, C.; Hou, X.; Zhang, P.; Rizzo, W. B.; Wood, J. R.; Cupp, A. S.; Davis, J. S.

10.1101/2020.02.13.948117 — cell biology — Posted on 2020-02-13

2102 How young is your Muscle? A Machine Learningframework for motor functional assessment with ageingby NMF based analysis of HD-sEMG signal.

BANERJEE, S.

10.1101/2020.02.12.946343 — bioengineering — Posted on 2020-02-13

2103 Parallel processing of sensory cue and spatial information in the Dentate Gyrus

Tuncdemir, S. N.; Grosmark, A. D.; Turi, G.; Shank, A.; Bowler, J.; Ordek, G.; Losonczy, A.; Hen, R.; Lacefield, C. O.

10.1101/2020.02.13.947903 — neuroscience — Posted on 2020-02-13

2104 Single exposure to social defeat or immobilization stress fails to induce lasting alterations in general anxiety and hippocampal neurogenesis in Wistar and wild-type Groningen rats

Patel, D.; Koutlas, I.; H. de Waard, S.; Buwalda, B.

10.1101/2020.02.12.946186 — neuroscience — Posted on 2020-02-13

2105 Induced copy-back RNA synthesis as a novel therapeutic mechanism against RNA viruses

Janissen, R.; Woodman, A.; Lee, K.-M.; Moustafa, I.; Fitzgerald, F.; Huang, P.-N.; Kuijpers, L.; Perkins, A. L.; Harki, D. A.; Arnold, J. J.; Solano, B.; Shih, S.-R.; Cameron, C. E.; Dekker, N. H.

10.1101/2020.02.12.946558 — microbiology — Posted on 2020-02-13

2106 The LUBAC participates in Lysophosphatidic Acid-induced NF-κB Activation

Douanne, T.; Chapelier, S.; Rottapel, R.; Gavard, J.; Bidere, N.

10.1101/2020.02.13.948125 — immunology — Posted on 2020-02-13

2107 Emerging viruses in British Columbia salmon discovered via a viral immune response biomarker panel and metatranscriptomic sequencing

Mordecai, G. J.; Di Cicco, E.; Gunther, O. P.; Schulze, A. D.; Kaukinen, K. H.; Li, S.; Tabata, A.; Ming, T. J.; Ferguson, H. W.; Suttle, C. A.; Miller, K. M.

10.1101/2020.02.13.948026 — genomics — Posted on 2020-02-13

2108 Single Cell Transcriptomics Reveals Dysregulated Cellular and Molecular Networks in a Fragile X Syndrome Model

Donnard, E.; Shu, H.; Garber, M. R.

10.1101/2020.02.12.946780 — genomics — Posted on 2020-02-13

2109 Splice-site Strength Estimation: A simple yet powerful approach to analyse RNA splicing

Dent, C. I.; Singh, S.; Mishra, S.; Shamaya, N.; Loo, K. P.; Dilip Sarwade, R.; Harrison, P. F.; Sureshkumar, S.; Powell, D.; Balasubramanian, S.

10.1101/2020.02.12.946756 — genetics — Posted on 2020-02-13

2110 Gene tree discord, simplex plots, and statistical tests under the coalescent

Allman, E. S.; Mitchell, J. D.; Rhodes, J. A.

10.1101/2020.02.13.948083 — evolutionary biology — Posted on 2020-02-13

2111 Climate and urbanization drive mosquito preference for humans

Rose, N. H.; Sylla, M.; Badolo, A.; Lutomiah, J.; Ayala, D.; Aribodor, O. B.; Ibe, N.; Akorli, J.; Otoo, S.; Mutebi, J.-P.; Kriete, A. L.; Ewing, E. G.; Sang, R.; Gloria-Soria, A.; Powell, J. R.; Baker, R. E.; White, B. J.; Crawford, J. E.; McBride, C. S.

10.1101/2020.02.12.939041 — evolutionary biology — Posted on 2020-02-13

2112 Inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stromal stiffening

Maller, O.; Drain, A. P.; Barrett, A. S.; Borgquist, S.; Ruffell, B.; Thanh, P. T.; Gruosso, T.; Kuasne, H.; Lakins, J. N.; Acerbi, I.; Barnes, J. M.; Nemkov, T.; Chauhan, A.; Gruenberg, J.; Nasir, A.; Bjarnadottir, O.; Werb, Z.; Kabos, P.; Hwang, E. S.; Park, M.; Coussens, L. M.; Nelson, A. C.; Hansen, K. C.; Weaver, V. M.

10.1101/2020.02.13.948141 — cancer biology — Posted on 2020-02-13

2113 Trophic guild and forest type explain phyllostomid bat abundance variation from human habitat disturbance.

Carballo-Morales, J. D.; Saldana-Vazquez, R. A.; Villalobos, F.

10.1101/2020.02.13.946889 — ecology — Posted on 2020-02-13

2114 The marine sponge Hymeniacidon perlevis is a globally-distributed invasive species

Turner, T. L.

10.1101/2020.02.13.948000 — zoology — Posted on 2020-02-13

2115 Differential submergence tolerance between juvenile and adult Arabidopsis plants involves the ANAC017 transcription factor

Bui, L. T.; Shukla, V.; Giorgi, F. M.; Trivellini, A.; Perata, P.; Licausi, F.; Giuntoli, B.

10.1101/2020.02.12.945923 — plant biology — Posted on 2020-02-13

2116 Pantoea ananatis defeats Allium chemical defenses with a plasmid-borne virulence gene cluster

Stice, S. P.; Thao, K. K.; Khang, C. H.; Baltrus, D. A.; Dutta, B.; Kvitko, B. H.

10.1101/2020.02.12.945675 — plant biology — Posted on 2020-02-13

2117 Cryptic diversity in the model fern genus Ceratopteris (Pteridaceae)

Kinosian, S. P.; Pearse, W. D.; Wolf, P. G.

10.1101/2020.02.12.946202 — plant biology — Posted on 2020-02-13

2118 Delay-period activity in frontal, parietal, and occipital cortex tracks different attractor dynamics in visual working memory

Yu, Q.; Panichello, M.; Cai, Y.; Postle, B. R.; Buschman, T. J.

10.1101/2020.02.13.947887 — neuroscience — Posted on 2020-02-13

2119 Dynamic Vision Training Transfers Positively to Batting Performance Among Collegiate Baseball Batters

Liu, S.; Ferris, L. M.; Hilbig, S.; Asamoa, E.; LaRue, J. L.; Lyon, D. W.; Connolly, K.; Port, N.; Appelbaum, L. G.

10.1101/2020.02.12.945824 — neuroscience — Posted on 2020-02-13

2120 Reduced dopamine signaling impacts pyramidal neuron excitability in mouse motor cortex

Swanson, O. K.; Semaan, R.; Maffei, A.

10.1101/2020.02.12.946301 — neuroscience — Posted on 2020-02-13

2121 Second messenger control of mRNA translation by dynamic ribosome modification

Grenga, L.; Little, R. H.; Chandra, G.; Woodcock, S. D.; Saalbach, G.; Morris, R. J.; Malone, J. G.

10.1101/2020.02.13.947879 — microbiology — Posted on 2020-02-13

2122 Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili

Koch, M. D.; Fei, C.; Wingreen, N. S.; Shaevitz, J. W.; Gitai, Z.

10.1101/2020.02.12.946426 — microbiology — Posted on 2020-02-13

2123 Metagenomic insights into the metabolism and ecologic functions of the widespread DPANN archaea from deep-sea hydrothermal vents

Cai, R.; Zhang, J.; liu, r.; Sun, C.

10.1101/2020.02.12.946848 — microbiology — Posted on 2020-02-13

2124 On Contamination of Symbolic Datasets

Pearson, A.; Lladser, M. E.

10.1101/2020.02.13.947754 — genomics — Posted on 2020-02-13

2125 Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates

Yang, L.; Emerman, M.; Malik, H. S.; McLaughlin, R. N.

10.1101/2020.02.12.944629 — genomics — Posted on 2020-02-13

2126 Mitogenome diversity of Aedes (Stegomyia) albopictus: Detection of multiple introduction events in Portugal and potential within-country dispersal

Ze-Ze, L.; Borges, V.; Osorio, H. C.; Machado, J.; Gomes, J. P.; Alves, M. J.

10.1101/2020.02.12.945741 — genomics — Posted on 2020-02-13

2127 Widespread selection against deleterious mutations in the Drosophila genome

Khromov, P.; Morozov, A. V.

10.1101/2020.02.12.946392 — evolutionary biology — Posted on 2020-02-13

2128 A Total-Evidence Dated Phylogeny of Echinoids and the Evolution of Body Size across Adaptive Landscape

Mongiardino Koch, N.; Thompson, J. R.

10.1101/2020.02.13.947796 — evolutionary biology — Posted on 2020-02-13

2129 A trans-eQTL network regulates osteoclast multinucleation and bone mass

Pereira, M.; Ko, J.-H.; Logan, J.; Protheroe, H.; Kim, K.-B.; Tan, A. L. M.; Park, K.-S.; Rotival, M.; Petretto, E.; Bassett, J. H. D.; Williams, G. R.; Behmoaras, J.

10.1101/2020.02.13.947705 — cell biology — Posted on 2020-02-13

2130 Neu-p11 induces NLRP3 inflammasome-induced pyroptosis via provoking NOX4-mediated mitochondrial oxidative injury in chordoma cells

Zhang, S.

10.1101/2020.02.12.946665 — cancer biology — Posted on 2020-02-13

2131 Poor availability of context-specific evidence hampers decision-making in conservation

Christie, A. P.; Amano, T.; Martin, P. A.; Petrovan, S. O.; Shackelford, G. E.; Simmons, B. I.; Smith, R. K.; Williams, D. R.; Wordley, C. F. R.; Sutherland, W. J.

10.1101/2020.02.13.946954 — ecology — Posted on 2020-02-13

2132 Predicting molecular subtypes of breast cancer using pathological images by deep convolutional neural network from public dataset

Phan, N. N.; Huang, C.-C.; Chuang, E. Y.

10.1101/2020.02.12.946723 — bioinformatics — Posted on 2020-02-13

2133 The Neural Basis for a Persistent Internal State in Drosophila Females

Deutsch, D.; Pacheco, D. A.; Encarnacion-Rivera, L. J.; Pereira, T.; Fathy, R.; Calhoun, A. J.; Eireland, E. C.; Burke, A. T.; Dorkenwald, S.; McKellar, C.; Macrina, T.; Lu, R.; Lee, K.; Kemnitz, N.; Ih, D.; Castro, M.; Halageri, A.; Jordan, C.; Silversmith, W.; Wu, J.; Seung, H. S.; Murthy, M.

10.1101/2020.02.13.947952 — neuroscience — Posted on 2020-02-13

2134 Characterising the mechanism of action of an ancient antimicrobial, honey, using modern transcriptomics

Bouzo, D.; Cokcetin, N. N.; Li, L.; Ballerin, G.; Bottomley, A. L.; Lazenby, J.; Whitchurch, C. B.; Paulsen, I. T.; Hassan, K. A.; Harry, E. J.

10.1101/2020.02.12.946830 — microbiology — Posted on 2020-02-13

2135 Targeted surveillance strategies for efficient detection of novel antibiotic resistance variants

Hicks, A. L.; Kissler, S. M.; Mortimer, T. D.; Ma, K. C.; Taiaroa, G.; Ashcroft, M.; Williamson, D. A.; Lipsitch, M.; Grad, Y. H.

10.1101/2020.02.12.946533 — genomics — Posted on 2020-02-13

2136 New functional identity of the essential inner membrane protein YejM: the cardiolipin translocator is also a metalloenzyme

Gabale, U.; Pena Palomino, P. A.; Kim, H.; Chen, W.; Ressl, S.

10.1101/2020.02.13.947838 — biophysics — Posted on 2020-02-13

2137 DeepTracer: Predicting Backbone Atomic Structure from High Resolution Cryo-EM Density Maps of Protein Complexes

Pfab, J.; Si, D.

10.1101/2020.02.12.946772 — bioinformatics — Posted on 2020-02-13

2138 Spage2vec: Unsupervised detection of spatial gene expression constellations

Partel, G.; Wahlby, C.

10.1101/2020.02.12.945345 — bioinformatics — Posted on 2020-02-13

2139 The BRPF1 bromodomain is a molecular reader of di-acetyllysine

Obi, J. O.; Lubula, M. Y.; Cornilescu, G.; Henrickson, A.; McGuire, K.; Evans, C. M.; Phillips, M.; Demeler, B.; Markley, J. L.; Glass, K. C.

10.1101/2020.02.13.948091 — biochemistry — Posted on 2020-02-13

2140 Parallel alpine differentiation in Arabidopsis arenosa

Knotek, A.; Konecna, V.; Wos, G.; Pozarova, D.; Sramkova, G.; Bohutinska, M.; Zeisek, V.; Marhold, K.; Kolar, F.

10.1101/2020.02.13.948158 — plant biology — Posted on 2020-02-13

2141 Modulation of spatial cue processing across the lifespan: a geometric polarization of space restores allocentric navigation strategies in children and older adults

Becu, M.; Sheynikhovich, D.; Ramanoel, S.; Tatur, G.; Ozier-Lafontaine, A.; Sahel, J.-A.; ARLEO, A.

10.1101/2020.02.12.945808 — neuroscience — Posted on 2020-02-13

2142 Macrophages transfer mitochondria to neurons to resolve inflammatory pain

Raoof, R.; van der Vlist, M.; Willemen, H. L. D. M.; Prado, J.; Versteeg, S.; Vos, M.; Lonkhorst, R. E.; Pasterkamp, R. J.; Khoury-Hanold, W.; Meyaard, L.; Eijkelkamp, N.

10.1101/2020.02.12.940445 — neuroscience — Posted on 2020-02-13

2143 Brain activation and connectivity in anorexia nervosa and body dysmorphic disorder when viewing bodies: relationships to clinical symptoms and perception of appearance

Moody, T. D.; Morfini, F.; Cheng, G.; Sheen, C. L.; Kerr, W.; Strober, M.; Feusner, J. D.

10.1101/2020.02.12.934083 — neuroscience — Posted on 2020-02-13

2144 Alteration of Power Law Scaling of Spontaneous Brain Activity in Schizophrenia

Lee, Y.-J.; Huang, S.-Y.; Lin, C.-P.; Tsai, S.-J.; Yang, A. C.

10.1101/2020.02.13.946657 — neuroscience — Posted on 2020-02-13

2145 Quantitative assessment of pain threshold induced by a single-pulse transcranial magnetic stimulation

Tani, K.; Hirata, A.; Tanaka, S.

10.1101/2020.02.13.946921 — neuroscience — Posted on 2020-02-13

2146 Model-based detection of putative synaptic connections from spike recordings with latency and type constraints

Ren, N.; Ito, S.; Hafizi, H.; Beggs, J. M.; Stevenson, I. H.

10.1101/2020.02.12.944496 — neuroscience — Posted on 2020-02-13

2147 Genomic study of oral lichen planus and oral microbiome with RNAseq

Zhong, E. F.; Chang, A.; Stucky, A.; Chen, X.; Mundluru, T.; Khalifeh, M.; Sedghizadeh, P. P.

10.1101/2020.02.12.946863 — molecular biology — Posted on 2020-02-13

2148 Phylogenetic background and habitat drive the genetic diversification of Escherichia coli

Touchon, M.; Perrin, A.; De Sousa, J. A. M.; Vangchhia, B.; burn, S.; O'brien, C.; Denamur, E.; Gordon, D.; Rocha, E. P.

10.1101/2020.02.12.945709 — microbiology — Posted on 2020-02-13

2149 Intracellular Lipid Droplet Accumulation Occurs Early Following Viral Infection and Is Required for an Efficient Interferon Response

Monson, E. A.; Crosse, K. M.; Duan, E.; Chen, W.; O'Shea, R. D.; Wakem, L. M.; Whelan, D. R.; Helbig, K. J.

10.1101/2020.02.12.946749 — microbiology — Posted on 2020-02-13

2150 Suppressors of YpsA-mediated cell division inhibition in Bacillus subtilis

Brzozowski, R. S.; Tomlinson, B. R.; Sacco, M. D.; Chen, J. J.; Ali, A. N.; Chen, Y.; Shaw, L. N.; Eswara, P. J.

10.1101/2020.02.12.946632 — microbiology — Posted on 2020-02-13

2151 Genetic Architecture of Complex Traits and Disease Risk Predictors

Yong, S. Y.; Raben, T. G.; Lello, L.; Hsu, S. D. H.

10.1101/2020.02.12.946608 — genomics — Posted on 2020-02-13

2152 Genome-enabled insights into the biology of thrips as crop pests

Rotenberg, D.; Baumann, A. A.; Ben-Mahmoud, S.; Christiaens, O.; Dermauw, W.; Ioannidis, P.; Jacobs, C. G. C.; Vargas Jentzsch, I. M.; Oliver, J. E.; Poelchau, M. F.; Rajarapu, S. P.; Schneweis, D. J.; Snoeck, S.; Taning, C. N. T.; Wei, D.; Widana-Gamage, S. M. K.; Hughes, D. S. T.; Murali, S. C.; Bailey, S.; Bejerman, N. E.; Holmes, C. J.; Jennings, E. C.; Rosendale, A. J.; Rosselot, A.; Hervey, K.; Schneweis, B. A.; Cheng, S.; Childers, C.; Simao, F. A.; Dietzgen, R. G.; Chao, H.; Dinh, H.; Doddapaneni, H. V.; Dugan, S.; Han, Y.; Lee, S. L.; Muzny, D. M.; Qu, J.; Worley, K. C.; Benoit, J. B.

10.1101/2020.02.12.941716 — genomics — Posted on 2020-02-13

2153 Animal movement in pastoralist populations and implications for pathogen spread and control

Omondi, G. P.; Obanda, V.; VanderWaal, K.; Deen, J.; Travis, D. A.

10.1101/2020.02.12.946467 — ecology — Posted on 2020-02-13

2154 The hidden land use cost of widespread cover cropping

Runck, B.; Khoury, C.; Ewing, P.; Kantar, M.

10.1101/2020.02.13.947994 — ecology — Posted on 2020-02-13

2155 The effect of terminal globular domains on the response of recombinant mini-spidroins to fiber spinning triggers

Finnigan, W.; Robert, A. D.; Scrutton, N.; Breitling, R.; Blaker, J.; Takano, E.

10.1101/2020.02.13.940478 — bioengineering — Posted on 2020-02-13

2156 Spatial orientation based on multiple visual cues in monarch butterflies

Franzke, M.; Kraus, C.; Dreyer, D.; Pfeiffer, K.; Beetz, M. J.; Stoeckl, A. L.; Foster, J. J.; Warrant, E. J.; el Jundi, B.

10.1101/2020.02.13.947739 — animal behavior and cognition — Posted on 2020-02-13

2157 TiFoSi: an Efficient Tool for Mechanobiology Simulations of Epithelia

Canela-Xandri, O.; Anbari, S.; Buceta, J.

10.1101/2020.02.12.933903 — systems biology — Posted on 2020-02-13

2158 Self-assembly based post-translational protein oscillators

Kimchi, O.; Goodrich, C. P.; Courbet, A.; Curatolo, A. I.; Woodall, N. B.; Baker, D.; Brenner, M. P.

10.1101/2020.02.12.946145 — systems biology — Posted on 2020-02-13

2159 Controlling for the effect of arterial-CO2 fluctuations in resting-state fMRI: Comparing end-tidal CO2 clamping and retroactive CO2 correction

Golestani, A. M.; Chen, J. J.

10.1101/2020.02.12.945881 — neuroscience — Posted on 2020-02-13

2160 Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans

Topalovic, U.; Aghajan, Z. M.; Villaroman, D.; Hiller, S.; Christov-Moore, L.; Wishard, T. J.; Stangl, M.; Hasulak, N. R.; Inman, C. S.; Fields, T. A.; Eliashiv, D.; Fried, I.; Suthana, N. A.

10.1101/2020.02.12.946434 — neuroscience — Posted on 2020-02-13

2161 Diversification of perceptual mechanisms underlying preserved multisensory behaviour in healthy aging

Park, H.; Kayser, C.

10.1101/2020.02.12.945949 — neuroscience — Posted on 2020-02-13

2162 Development of Small Molecule MEIS Inhibitors that modulate HSC activity

Turan, R. D.; Albayrak, E.; Uslu, M.; Siyah, P.; Alyazici, L. Y.; Kalkan, B. M.; Aslan, G. S.; Yucel, D.; Aksoz, M.; Tuysuz, E. C.; Meric, N.; Durdagi, S.; Gulbas, Z.; Kocabas, F.

10.1101/2020.02.12.946491 — molecular biology — Posted on 2020-02-13

2163 No detectable alloreactive transcriptional responses during donor-multiplexed single-cell RNA sequencing of peripheral blood mononuclear cells

McGinnis, C. S.; Siegel, D. A.; Xie, G.; Stone, M.; Gartner, Z. J.; Roan, N. R.; Lee, S. A.

10.1101/2020.02.12.946509 — genomics — Posted on 2020-02-13

2164 Analysis of cardiac magnetic resonance imaging traits in 29,000 individuals reveals shared genetic basis with dilated cardiomyopathy

Pirruccello, J.; Bick, A.; Wang, M.; Chaffin, M.; Lubitz, S. A.; Ellinor, P. T.; Khera, A. V.; Kathiresan, S.; Aragam, K. G.

10.1101/2020.02.12.946038 — genomics — Posted on 2020-02-13

2165 Ecological theory applied to environmental metabolomes reveals compositional divergence despite conserved molecular properties

Danczak, R. E.; Goldman, A. E.; Chu, R. K.; Toyoda, J. G.; Garayburu-Caruso, V. A.; Tolic, N.; Graham, E. B.; Morad, J.; Renteria, L.; Wells, J. R.; Herzog, S. P.; Ward, A. S.; Stegen, J. C.

10.1101/2020.02.12.946459 — ecology — Posted on 2020-02-13

2166 A mathematical model of ctDNA shedding predicts tumor detection size

Avanzini, S.; Kurtz, D. M.; Chabon, J. J.; Hori, S. S.; Gambhir, S. S.; Alizadeh, A. A.; Diehn, M.; Reiter, J. G.

10.1101/2020.02.12.946228 — cancer biology — Posted on 2020-02-13

2167 Long-term repeatability in social behaviours suggests stable social phenotypes in wild chimpanzees

Tkaczynski, P. J.; Mielke, A.; Samuni, L.; Preis, A.; Wittig, R.; Crockford, C.

10.1101/2020.02.12.945857 — animal behavior and cognition — Posted on 2020-02-13

2168 Turning the screw: engineering extreme pH resistance in Escherichia coli through combinatorial synthetic operons

de Siqueira, G. M. V.; Silva-Rocha, R.; Guazzaroni, M. E.

10.1101/2020.02.12.946095 — synthetic biology — Posted on 2020-02-13

2169 Alzheimer's disease-relevant tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model

Guha, S.; Fischer, S.; Johnson, G.; Nehrke, K.

10.1101/2020.02.12.946004 — neuroscience — Posted on 2020-02-13

2170 Loop extrusion as a mechanism for DNA Double-Strand Breaks repair foci formation

Arnould, C.; Rocher, V.; Clouaire, T.; Caron, P.; Mangeot, P. E.; Ricci, E. P.; Mourad, R.; Noordermeer, D.; Legube, G.

10.1101/2020.02.12.945311 — molecular biology — Posted on 2020-02-13

2171 Functional characterization of thousands of type 2 diabetes-associated and chromatin-modulating variants under steady state and endoplasmic reticulum stress

Khetan, S.; Kales, S.; Kursawe, R.; Jillette, A.; Reilly, S. K.; Ucar, D.; Tewhey, R.; Stitzel, M. L.

10.1101/2020.02.12.939348 — genomics — Posted on 2020-02-13

2172 Mitochondrial respiration is required to provide amino acids during fermentative proliferation of fission yeast

Malecki, M.; Kamrad, S.; Ralser, M.; Bahler, J.

10.1101/2020.02.12.946111 — genetics — Posted on 2020-02-13

2173 Formation of aggregates, icosahedral structures and percolation clusters of fullerenes in lipids bilayers: The key role of lipid saturation

Nisoh, N.; Jarerattanachart, V.; Karttunen, M.; Wong-ekkabut, J.

10.1101/2020.02.12.946152 — biophysics — Posted on 2020-02-13

2174 The estrogenic pathway modulates non-breeding female aggression in a teleost fish

Zubizarreta, L.; Silva, A.; Quintana, L. A.

10.1101/2020.02.12.946327 — animal behavior and cognition — Posted on 2020-02-13

2175 Traumatic stress history interacts with chronic peripheral inflammation to alter mitochondrial function of synaptosomes in a sex-specific manner

Shaw, G.; Hyer, M.; Targett, I.; Council, K.; Dyer, S.; Turkson, S.; Burns, C.; Neigh, G.

10.1101/2020.02.12.946079 — neuroscience — Posted on 2020-02-13

2176 Inter-species h-current differences influence resonant properties in a novel human cortical layer 5 neuron model

Rich, S.; Moradi-Chameh, H.; Sekulic, V.; Skinner, F. K.; Valiante, T. A.

10.1101/2020.02.12.945980 — neuroscience — Posted on 2020-02-13

2177 The cerebellum recalibrates a feedback controller involved in motor control

Markov, D. A.; Kist, A. M.; Petrucco, L.; Portugues, R.

10.1101/2020.02.12.945956 — neuroscience — Posted on 2020-02-13

2178 Enhancing CRISPR deletion via pharmacological delay of DNA-PK

Bosch, N.; Medova, M.; Esposito, R.; Pulido-Quetglas, C.; Zimmer, Y.; Johnson, R.

10.1101/2020.02.12.945907 — molecular biology — Posted on 2020-02-13

2179 MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development

Parada, G. E.; Munita, R.; Georgakopoulos-Soares, I.; Fernandez, H.; Metzakopian, E.; Andres, M. E.; Miska, E. A.; Hemberg, M.

10.1101/2020.02.12.945683 — genomics — Posted on 2020-02-13

2180 Molecular dissection of neurodevelopmental disorder-causing mutations in CYFIP2

Schaks, M.; Rottner, K.

10.1101/2020.02.11.943332 — cell biology — Posted on 2020-02-13

2181 Integrative kinomics reveals kinase-driven subtypes of gastric adenocarcinomas with sunitinib as a potential common inhibitor

Tapken, M. J.; Haag, G. M.; Jaeger, D.; Froehling, S.; Mock, A.

10.1101/2020.02.12.944371 — cancer biology — Posted on 2020-02-13

2182 OTX2 non-cell autonomous activity regulates inner retinal function

Torero Ibad, R.; Mazhar, B.; Vincent, C.; Bernard, C.; Degardin, J.; Simonutti, M.; Lamonerie, T.; Di Nardo, A.; Prochiantz, A. L.; Moya, K. L.

10.1101/2020.02.12.945584 — neuroscience — Posted on 2020-02-13

2183 Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12

Chen, Z.; Wasney, G. A.; Picaud, S.; Filippakopoulos, P.; Vedadi, M.; D'Angiolella, V.; Bullock, A. N.

10.1101/2020.02.12.945758 — molecular biology — Posted on 2020-02-13

2184 The major subunit of widespread competence (pseudo)pili exhibits a novel and conserved type IV pilin fold

Sheppard, D.; Berry, J.-L.; Denise, R.; Rocha, E. P.; Matthews, S. J.; Pelicic, V.

10.1101/2020.02.12.945410 — microbiology — Posted on 2020-02-13

2185 A genome assembly of the barley 'transformation reference' cultivar Golden Promise

Schreiber, M.; Mascher, M.; Wright, J.; Padmarasu, S.; Himmelbach, A.; Heavens, D.; Milne, L.; Clavijo, B. J.; Stein, N.; Waugh, R.

10.1101/2020.02.12.945550 — genomics — Posted on 2020-02-13

2186 phyloregion: R package for biogeographic regionalization and spatial conservation

Daru, B. H.; Karunarathne, P.; Schliep, K.

10.1101/2020.02.12.945691 — bioinformatics — Posted on 2020-02-13

2187 Towards understanding the structure of the capsid of Banana Bunchy Top Virus

Venkataraman, S.; Sairam, S.; Ramasamy, S.; Handanahalli, S.

10.1101/2020.02.12.945212 — bioinformatics — Posted on 2020-02-13

2188 Structure of heme d1-free cd1 nitrite reductase NirS

Kluenemann, T.; Blankenfeldt, W.

10.1101/2020.02.12.945543 — biochemistry — Posted on 2020-02-13

2189 Synergism and antagonism of two distinct, but confused, Nrf1 factors in integral regulation of the nuclear-to mitochondrial respiratory and antioxidant transcription networks

Zhang, S.; Deng, Y.; Xiang, Y.; Hu, S.; Qiu, L.; Zhang, Y.

10.1101/2020.02.12.945568 — molecular biology — Posted on 2020-02-13

2190 Single-cell transcriptomic profile reveals macrophage heterogeneity in medulloblastoma and their treatment-dependent recruitment

Dang, M. T.; Gonzalez, M.; Gaonkar, K. S.; Rathi, K. S.; Young, P.; Arif, S.; Zhai, L.; Alam, M.; Devalaraja, S.; Tsun, T.; Folkert, I.; Raman, P.; Rokita, J. L.; Martinez, D.; Taroni, J.; Shapiro, J.; Greene, C. S.; Savonen, C.; Hakonarson, H.; Curran, T.; Haldar, M.

10.1101/2020.02.12.945642 — cancer biology — Posted on 2020-02-13

2191 Biomarker signatures of quality for nasal chondrocyte-derived engineered cartilage

Asnaghi, M. A.; Power, L. J.; Barbero, A.; Haug, M.; Koeppl, R.; Wendt, D.; Martin, I.

10.1101/2020.02.12.945527 — bioengineering — Posted on 2020-02-13

2192 A Front-Back Confusion Metric in Horizontal Sound Localization: The FBC Score

Fischer, T.; Caversaccio, M.; Wimmer, W.

10.1101/2020.02.12.945303 — neuroscience — Posted on 2020-02-13

2193 Widespread targeting of development-related host transcription factors by phytoplasma effectors

Correa Marrero, M.; Capdevielle, S.; Huang, W.; Busscher, M.; Busscher-Lange, J.; de Ridder, D.; van Dijk, A. D. J.; Hogenhout, S. A.; Immink, R. G. H.

10.1101/2020.02.13.946517 — plant biology — Posted on 2020-02-13

2194 Reduced Suprathreshold Auditory Nerve Responses are Associated with Thinner Temporal Cortex and Slower Processing Speed in Presbycusis

Delano, P. H.; Belkhiria, C.; Vergara, R. C.; Martinez, M.; Leiva, A.; Andrade, M.; Marcenaro, B.; Torrente, M.; Maass, J. C.; Delgado, C.

10.1101/2020.02.12.945337 — neuroscience — Posted on 2020-02-13

2195 Adaptive laboratory evolution and reverse engineering of single-vitamin prototrophies in Saccharomyces cerevisiae.

Perli, T.; Moonen, D. P. I.; van den Broek, M.; Pronk, J. T.; Daran, J.-M. G.

10.1101/2020.02.12.945287 — microbiology — Posted on 2020-02-13

2196 Bacterial flagella disrupt host cell membranes and interact with cytoskeletal components

Wolfson, E. B.; Elvidge, J.; Tahoun, A.; Gillespie, T.; Mantell, J.; McAteer, S. P.; Rossez, Y.; Paxton, E.; Lane, F.; Shaw, D. J.; Gill, A. C.; Steveni, J.; Verkade, P.; Blocker, A.; Mahajan, A.; Gally, D. L.

10.1101/2020.02.12.945204 — microbiology — Posted on 2020-02-13

2197 The West African lungfish provides insights into the evolution of tetrapod tail regeneration

Verissimo, K. M.; Perez, L. N.; Dragalzew, A. C.; Senevirathne, G.; Darnet, S.; Mendes, W. R.; Neves, C. A.; dos Santos, E. M.; Moraes, C. N.; Shubin, N. H.; Froebisch, N. B.; Sousa, J. F.; Schneider, I.

10.1101/2020.02.12.946319 — evolutionary biology — Posted on 2020-02-13

2198 The irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived Transglutaminase 2

Berg, T. J.; Marques, C.; Pantazopoulou, V.; Johansson, E.; von Stedingk, K.; Lindgren, D.; Pietras, E. J.; Bergström, T.; Swartling, F. J.; Axelson, H.; Squatrito, M.; Pietras, A.

10.1101/2020.02.12.945329 — cancer biology — Posted on 2020-02-13

2199 No solid evidence of soil carbon loss under warming in tropical forests along a 3000 m elevation gradient

Luo, Z.; Guo, X.; Sun, O. J.

10.1101/2020.02.10.941310 — ecology — Posted on 2020-02-13

2200 Emergence of ribozyme and tRNA-like structures from mineral-rich muddy pools on prebiotic earth

Roy, S.; Bapat, N. V.; Derr, J.; Rajamani, S.; Sengupta, S.

10.1101/2020.02.12.944926 — biophysics — Posted on 2020-02-13

2201 Metabolic flexibility allows generalist bacteria to become dominant in a frequently disturbed ecosystem

Chen, Y.-J.; Leung, P. M.; Bay, S. K.; Hugenholtz, P.; Kessler, A. J.; Shelley, G.; Waite, D. W.; Cook, P. L. M.; Greening, C.

10.1101/2020.02.12.945220 — microbiology — Posted on 2020-02-13

2202 MPRAudit Quantifies the Fraction of Variance Described by Unknown Features in Massively Parallel Reporter Assays

Siegel, D. A.; Le Tonqueze, O.; Biton, A.; Erle, D. J.; Zaitlen, N.

10.1101/2020.02.12.945113 — bioinformatics — Posted on 2020-02-13

2203 Nanoscale pattern extraction from relative positions of sparse 3D localisations

Curd, A.; Leng, J.; Hughes, R.; Cleasby, A.; Rogers, B.; Trinh, C.; Baird, M.; Takagi, Y.; Tiede, C.; Sieben, C.; Manley, S.; Schlichthaerle, T.; Jungmann, R.; Ries, J.; Shroff, H.; Peckham, M.

10.1101/2020.02.13.947135 — cell biology — Posted on 2020-02-13

2204 An in vitro vesicle formation assay to analyze protein sorting in the secretory transport pathway

Huang, Y.; Yin, H.; Tang, X.; Wu, Q.; Wang, M.; Poljak, K.; Li, B.; Liu, Y.; Wu, Z.; Jiang, L.; Miller, E. A.; Yao, Z.-P.; Guo, Y.

10.1101/2020.02.12.945162 — cell biology — Posted on 2020-02-13

2205 PCNA activates the MutLγ endonuclease to promote meiotic crossing over

Hunter, N.; Kulkarni, D. S.; Owens, S.; Honda, M.; Ito, M.; Yang, Y.; Corrigan, M. W.; Chen, L.; Quan, A. L.

10.1101/2020.02.12.946020 — biochemistry — Posted on 2020-02-13

2206 Regulation of the MLH1-MLH3 endonuclease in meiosis

Cannavo, E.; Sanchez, A.; Anand, R.; Ranjha, L.; Hugener, J.; Adam, C.; Acharya, A.; Weyland, N.; Aran-Guiu, X.; Charbonnier, J.-B.; Hoffman, E. R.; Borde, V.; Matos, J.; Cejka, P.

10.1101/2020.02.12.946293 — biochemistry — Posted on 2020-02-13

2207 The C-terminus and Third Cytoplasmic Loop Cooperatively Activate Mouse Melanopsin Phototransduction

Valdez-Lopez, J. C.; Petr, S. T.; Donohue, M. P.; Bailey, R. J.; Gebreeziabher, M.; Cameron, E. G.; Wolf, J. B.; Szalai, V. A.; Robinson, P. R.

10.1101/2020.02.12.946129 — neuroscience — Posted on 2020-02-13

2208 Functional specialization of human salivary glands and origins of proteins intrinsic to human saliva

Saitou, M.; Gaylord, E.; Xu, D.; Neznanova, L.; Nathan, S.; Grawe, A.; Chang, J.; Ryan, W.; Ruhl, S.; Knox, S. M.; Gokcumen, O.

10.1101/2020.02.12.945659 — developmental biology — Posted on 2020-02-13

2209 A Myosin-7B dependent endocytosis pathway mediates cellular entry of α-Synuclein fibrils and polycation-bearing cargos

Zhang, Q.; Xu, Y.; Lee, J.; Jarnik, M.; Wu, X.; Bonifacino, J. S.; Shen, J.; Ye, Y.

10.1101/2020.02.12.946137 — cell biology — Posted on 2020-02-13

2210 The mechanical inhibition of the isolated Vo from V-ATPase for proton conductance

Kishikawa, J.-i.; Nakanishi, A.; Furuta, A.; Kato, T.; Namba, K.; Tamakoshi, M.; Mitsuoka, K.; Yokoyama, K.

10.1101/2020.02.13.946640 — biophysics — Posted on 2020-02-13

2211 Microtubule instability driven by longitudinal and lateral strain propagation

Igaev, M.; Grubmueller, H.

10.1101/2020.02.12.946418 — biophysics — Posted on 2020-02-13

2212 Teicoplanin potently blocks the cell entry of 2019-nCoV

Zhang, J.; Ma, X.; Yu, F.; Liu, J.; Zou, F.; Pan, T.; Zhang, H.

10.1101/2020.02.05.935387 — microbiology — Posted on 2020-02-13

2213 Evidence of recombination in coronaviruses implicating pangolin origins of nCoV-2019

Wong, M. C.; Javornik Cregeen, S. J.; Ajami, N. J.; Petrosino, J. F.

10.1101/2020.02.07.939207 — microbiology — Posted on 2020-02-13

2214 Novel hemorrhage models of cerebral cavernous malformations

Detter, M. R.; Shenkar, R.; Benavides, C. R.; Neilson, C. A.; Moore, T.; Lightle, R.; Hobson, N.; Shen, L.; Cao, Y.; Girard, R.; Zhang, D.; Griffin, E.; Gallione, C. J.; Awad, I. A.; Marchuk, D. A.

10.1101/2020.02.12.944421 — genetics — Posted on 2020-02-13

2215 Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

Ouspenskaia, T.; Law, T.; Clauser, K. R.; Klaeger, S.; Sarkizova, S.; Aguet, F.; Li, B.; Christian, E.; Knisbacher, B. A.; Le, P. M.; Hartigan, C. R.; Keshishian, H.; Apffel, A.; Oliveira, G.; Zhang, W.; Chow, Y. T.; Ji, Z.; Shukla, S. A.; Bachireddy, P.; Getz, G.; Hacohen, N.; Keskin, D. B.; Carr, S. A.; Wu, C. J.; Regev, A.

10.1101/2020.02.12.945840 — cancer biology — Posted on 2020-02-13

2216 Divergent ion selectivity and sensitivity to anti-hypertensive and non-steroidal anti-inflammatory drugs of DEG/ENaC/ASIC channels in C. elegans

Fechner, S.; D'Alessandro, I.; Wang, L.; Tower, C.; Tao, L.; Goodman, M. B.

10.1101/2020.02.12.946681 — biophysics — Posted on 2020-02-13

2217 Potentially highly potent drugs for 2019-nCoV

Nguyen, D.; Gao, K.; Chen, J.; Wang, R.; Wei, G.

10.1101/2020.02.05.936013 — bioinformatics — Posted on 2020-02-13

2218 F-box protein MEC-15 promotes microtubule stability and neurite growth by antagonizing the HSP90 chaperone network in Caenorhabditis elegans

Zheng, C.; Atlas, E.; Lee, H. M. T.; Jao, S. L. J.; Nguyen, K. C. Q.; Hall, D. H.; Chalfie, M.

10.1101/2020.02.13.944967 — developmental biology — Posted on 2020-02-13

2219 A novel temporal identity window generates alternating cardinal motor neuron subtypes in a single progenitor lineage

Doe, C. Q.; Lai, S.-L.; Yazejian, R.; Seroka, A.

10.1101/2020.02.12.946442 — developmental biology — Posted on 2020-02-13

2220 Host-induced gene silencing involves transfer of dsRNA-derived siRNA via extracellular vesicles

10.1101/2020.02.12.945154 — plant biology — Posted on 2020-02-13

2221 Radixin modulates stereocilia function and contributes to cochlear amplification

Prasad, S.; Vona, B.; Dineiro Soto, M.; Costales, M.; Gonzalez-Aguado, R.; Romero Fontalba, A. M.; Diego-Perez, C.; Subasioglu, A.; Bademci, G.; Tekin, M.; Cabanillas, R.; Cadinanos, J.; Fridberger, A.

10.1101/2020.02.11.944355 — neuroscience — Posted on 2020-02-13

2222 Cryo-EM structures and functional properties of CALHM channels of the human placenta

Drozdzyk, K.; Sawicka, M.; Bahamonde-Santos, M.-I.; Jonas, Z.; Deneka, D.; Albrecht, C.; Dutzler, R.

10.1101/2020.02.11.944231 — biophysics — Posted on 2020-02-13

2223 Single mosquito metatranscriptomics recovers mosquito species, blood meal sources, and microbial cargo, including viral dark matter

Batson, J.; Kistler, A.; Dudas, G.; Li, L.; Ratnasari, K.; Haas-Stapleton, E.; Logan, P.; Retallack, H.

10.1101/2020.02.10.942854 — microbiology — Posted on 2020-02-13

2224 SECAT: Quantifying differential protein-protein interaction states by network-centric analysis

Rosenberger, G.; Heusel, M.; Bludau, I.; Collins, B. C.; Martelli, C.; Williams, E.; Xue, P.; Liu, Y.; Aebersold, R.; Califano, A.

10.1101/819755 — systems biology — Posted on 2020-02-13

2225 Co-expression clustering across flower development identifies modules for diverse floral forms in Achimenes (Gesneriaceae)

Roberts, W. R.; Roalson, E. H.

10.1101/817221 — plant biology — Posted on 2020-02-13

2226 Disruption of the transcription factor NEUROD2 causes an autism syndrome via cell-autonomous defects in cortical projection neurons

10.1101/296889 — neuroscience — Posted on 2020-02-13

2227 Modulation of white matter bundle connectivity in the presence of axonal truncation pathologies

Smith, R. E.; Calamante, F.; Gajamange, S.; Kolbe, S.; Connelly, A.

10.1101/2020.01.14.903559 — neuroscience — Posted on 2020-02-13

2228 A head-fixation system for continuous monitoring of force generated during behavior

Hughes, R.; Bakhurin, K.; Barter, J.; Zhang, J.; Yin, H.

10.1101/868703 — neuroscience — Posted on 2020-02-13

2229 Self-generated whisker movements drive state-dependent sensory input to developing barrel cortex

Dooley, J. C.; Glanz, R. M.; Sokoloff, G.; Blumberg, M. S.

10.1101/2020.01.21.914259 — neuroscience — Posted on 2020-02-13

2230 Visual and semantic representations predict subsequent memory in perceptual and conceptual memory tests

Davis, S. W.; Geib, B.; Wing, E.; Wang, W.-C.; Hovhannisyan, M.; Monge, Z.; Cabeza, R.

10.1101/2020.02.11.944801 — neuroscience — Posted on 2020-02-13

2231 Rapid and real-time identification of fungi up to the species level with long amplicon Nanopore sequencing from clinical samples.

D'Andreano, S.; Cusco, A.; Francino, O.

10.1101/2020.02.06.936708 — microbiology — Posted on 2020-02-13

2232 Intravital quantification of absolute cytoplasmic B cell calcium reveals dynamic signaling across B cell differentiation stages

Ulbricht, C.; Leben, R.; Rakhymzhan, A.; Kirchhoff, F.; Nitschke, L.; Radbruch, H.; Niesner, R. A.; Hauser, A. E.

10.1101/2019.12.13.872820 — immunology — Posted on 2020-02-13

2233 Analysis of KSHV B lymphocyte lineage tropism in human tonsil reveals efficient infection of CD138+ plasma cells

Aalam, F.; Nabiee, R.; Castano, J. R.; Totonchy, J.

10.1101/2020.01.17.910612 — immunology — Posted on 2020-02-13

2234 Mathematical Modelling Reveals Selective Dynamics Invisible to Imaging

Edwards, J.; Marusyk, A.; Basanta, D.

10.1101/2020.02.11.944843 — cancer biology — Posted on 2020-02-13

2235 Viral integration transforms chromatin to drive oncogenesis

Karimzadeh, M.; Arlidge, C.; Rostami, A.; Lupien, M.; Bratman, S. V.; Hoffman, M. M.

10.1101/2020.02.12.942755 — cancer biology — Posted on 2020-02-13

2236 Association of Bacteroides acidifaciens relative abundance with high-fibre diet-associated radiosensitisation

Then, C. K.; Paillas, S.; Hampson, A.; Kiltie, A.

10.1101/846436 — cancer biology — Posted on 2020-02-13

2237 RNA structure prediction using positive and negative evolutionary information

Rivas, E.

10.1101/2020.02.04.933952 — bioinformatics — Posted on 2020-02-13

2238 Single-Cell Analysis of the 3D Topologies of Genomic Loci Using Genome Architecture Mapping

Welch, L. R.; Baugher, C.; Zhang, Y.; Davis, T.; Marzluff, W. F.; Welch, J. D.; Pombo, A.

10.1101/2020.02.10.941047 — bioinformatics — Posted on 2020-02-13

2239 Multisensory perception, verbal, visuo-spatial and motor working memory modulation after a single open- or closed-skill exercise session in children.

O'Brien, J.; Ottoboni, G.; Tessari, A.; Setti, A.

10.1101/2020.01.29.924563 — animal behavior and cognition — Posted on 2020-02-13

2240 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2020-02-13

2241 Domestication reprogrammed the budding yeast life cycle

De Chiara, M.; Barre, B. P.; Persson, K.; Onyetuga Chioma, A.; Irizar, A.; Schacherer, J.; Warringer, J.; Liti, G.

10.1101/2020.02.08.939314 — evolutionary biology — Posted on 2020-02-13

2242 DUX4 regulates oocyte to embryo transition in human

Vuoristo, S.; Hyden-Granskog, C.; Yoshihara, M.; Bhagat, S.; Gawriyski, L.; Jouhilahti, E.-M.; Damdimopoulos, A.; Ranga, V.; Tamirat, M.; Huhtala, M.; Hashimoto, K.; Krjutskov, K.; Recher, G.; Ezer, S.; Paluoja, P.; Paloviita, P.; Takegami, Y.; Kanemaru, A.; Lundin, K.; Airenne, T.; Otonkoski, T.; Tapanainen, J. S.; Kawaji, H.; Murakawa, Y.; Bürglin, T. R.; Varjosalo, M.; Johnson, M. S.; Tuuri, T.; Katayama, S.; Kere, J.

10.1101/732289 — developmental biology — Posted on 2020-02-13

2243 The localization of chitin synthase mediates the patterned deposition of chitin in developing Drosophila bristles.

Adler, P. N.

10.1101/718841 — developmental biology — Posted on 2020-02-13

2244 Optimal Design of Single-Cell Experiments within Temporally Fluctuating Environments

Fox, Z. R.; Neuert, G.; Munsky, B.

10.1101/812479 — systems biology — Posted on 2020-02-13

2245 Tough Hydrogel-Based Biocontainment of Engineered Organisms for Continuous, Self-Powered Sensing and Computation

Tang, T.-C.; Tham, E.; Liu, X.; Yehl, K.; Rovner, A. J.; Yuk, H.; Isaacs, F. J.; Zhao, X.; Lu, T. K.

10.1101/2020.02.11.941120 — synthetic biology — Posted on 2020-02-13

2246 Effect of Exogenous Amino Acids on Yield and Quality of Tartary Buckwheat in Non-saline and Saline-alkali Soil

Song, J.-N.; Wang, Y.-Q.; Li, F.-L.; Hu, Y.-J.; Yang, H.-B.

10.1101/2019.12.24.887778 — physiology — Posted on 2020-02-13

2247 Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles

Huang, Y.; Cheng, L.; Turchinovich, A.; Mahairaki, V.; Troncoso, J. C.; Pletnikov, O.; Haughey, N. J.; Vella, L. J.; Hill, A. F.; Zheng, L.; Witwer, K. W.

10.1101/2020.02.10.940999 — neuroscience — Posted on 2020-02-13

2248 Local sleep-like cortical reactivity in the awake brain after focal injury

Sarasso, S.; D'Ambrosio, S.; Fecchio, M.; Casarotto, S.; Vigano, A.; Landi, C.; Mattavelli, G.; Gosseries, O.; Quarenghi, M.; Laureys, S.; Devalle, G.; Rosanova, M.; Massimini, M.

10.1101/2019.12.19.882290 — neuroscience — Posted on 2020-02-13

2249 Early life glucocorticoid exposure modulates immune function in zebrafish (Danio rerio) larvae

van den Bos, R.; Cromwijk, S.; Tschigg, K.; Althuizen, J.; Zethof, J.; Whelan, R.; Flik, G.; Schaaf, M.

10.1101/2019.12.11.872903 — immunology — Posted on 2020-02-13

2250 Multi-omics Visualization Platform: An extensible Galaxy plug-In for multi-omics data visualization and exploration

McGowan, T.; Johnson, J. E.; Kumar, P.; Sajulga, R.; Mehta, S.; Jagtap, P. D.; Griffin, T. J.

10.1101/842856 — bioinformatics — Posted on 2020-02-13

2251 Time-varying transmission dynamics of Novel Coronavirus Pneumonia in China

Liu, T.; Hu, J.; Xiao, J.; He, G.; Kang, M.; Rong, Z.; Lin, L.; Zhong, H.; Huang, Q.; Deng, A.; Zeng, W.; Tan, X.; Zeng, S.; Zhu, Z.; Li, J.; Gong, D.; Wan, D.; Chen, S.; Guo, L.; Li, Y.; Sun, L.; Liang, W.; Song, T.; He, J.; Ma, W.

10.1101/2020.01.25.919787 — systems biology — Posted on 2020-02-13

2252 Phase-specific manipulation of neural oscillatory activity by transcranial alternating current stimulation

Fiene, M.; Schwab, B. C.; Misselhorn, J.; Herrmann, C. S.; Schneider, T. R.; Engel, A. K.

10.1101/579631 — neuroscience — Posted on 2020-02-13

2253 A computational mechanism for seeing dynamic deformation

Kawabe, T.; Sawayama, M.

10.1101/682336 — neuroscience — Posted on 2020-02-13

2254 TWO-SIGMA: a novel TWO-component SInGle cell Model-based Association method for single-cell RNA-seq data

Van Buren, E.; Hu, M.; Weng, C.; Jin, F.; Li, Y.; Wu, D.; Li, Y.

10.1101/709238 — genomics — Posted on 2020-02-13

2255 Transcriptome analysis reveals salinity responses in four Tartary buckwheat cultivars

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2020-02-13

2256 Intratumor Heterogeneity and Evolution of Colorectal Cancer

Banerjee, S.; Zhang, X.; Kuang, S.; Wang, J.; Li, L.; Fan, G.; Luo, Y.; Sun, S.; Han, P.; Wu, Q.; Yang, S.; Ji, X.; Li, Y.; Deng, L.; Tian, X.; Wang, Z.; Zhang, Y.; Wu, K.; Zhu, S.; Bolund, L.; Yang, H.; Xu, X.; Liu, J.; Lu, Y.; Liu, X.

10.1101/2020.01.13.904276 — genetics — Posted on 2020-02-13

2257 Kinetic control of stationary flux ratios for a wide range of biochemical processes

Mallory, J. D.; Kolomeisky, A.; Igoshin, O. A.

10.1101/858126 — biophysics — Posted on 2020-02-13

2258 Dissecting heterogeneous cell-populations across drug and disease conditions with PopAlign

Chen, S.; Park, J. H.; Rivaud, P.; Charles, E.; Haliburton, J.; Pichiorri, F.; Thomson, M.

10.1101/421354 — bioinformatics — Posted on 2020-02-13

2259 Automated Threshold Selection for Cryo-EM Density Maps

Pfab, J.; Si, D.

10.1101/657395 — bioinformatics — Posted on 2020-02-13

2260 Genomic loci susceptible to systematic sequencing bias in clinical whole genomes

Freeman, T. M.; Genomics England Research Consortium, ; Wang, D.; Harris, J.

10.1101/679423 — bioinformatics — Posted on 2020-02-13

2261 Overcoming high nanopore basecaller error rates for DNA storage via basecaller-decoder integration and convolutional codes

Chandak, S.; Neu, J.; Tatwawadi, K.; Mardia, J.; Lau, B.; Kubit, M.; Hulett, R.; Griffin, P.; Wootters, M.; Weissman, T.; Ji, H.

10.1101/2019.12.20.871939 — bioengineering — Posted on 2020-02-13

2262 Non-clonal emergence of colistin resistance associated with mutations in the BasRS two component system in Escherichia coli bloodstream isolates

Janssen, A. B.; Bartholomew, T. L.; Marciszewska, N. P.; Bonten, M.; Willems, R. J. L.; Bengoechea, J. A.; Schaik, W.

10.1101/864983 — microbiology — Posted on 2020-02-13

2263 BANDITS: Bayesian differential splicing accounting for sample-to-sample variability and mapping uncertainty

Tiberi, S.; Robinson, M.

10.1101/750018 — bioinformatics — Posted on 2020-02-13

2264 Interruption of Continuous Opioid Exposure Exacerbates Drug-Evoked Adaptations in the Mesolimbic Dopamine System

Lefevre, E. M.; Pisansky, M. T.; Toddes, C.; Baruffaldi, F.; Pravetoni, M.; Tian, L.; Kono, T. J.; Rothwell, P. E.

10.1101/646356 — neuroscience — Posted on 2020-02-13

2265 Dsuite - fast D-statistics and related admixture evidence from VCF files

Malinsky, M.; Matschiner, M.; Svardal, H.

10.1101/634477 — genomics — Posted on 2020-02-13

2266 Developmentally-orchestrated mitochondrial processes prime the selective inheritance against harmful mitochondrial DNA mutations

Chen, Z.; Wang, Z.-H.; Zhang, G.; Bleck, C. K. E.; Chung, D. J.; Madison, G.; Lindberg, E.; Combs, C.; Balaban, R. S.; Xu, H.

10.1101/646638 — genetics — Posted on 2020-02-13

2267 Inferred microbial networks lack replicability: consequences for next-generation biomonitoring

Pauvert, C.; Vallance, J.; Deliere, L.; Bohan, D. A.; Buee, M.; Vacher, C.

10.1101/642199 — ecology — Posted on 2020-02-13

2268 Regulated unbinding of ZAP70 at the T cell receptor by kinetic avidity

Goyette, J.; Depoil, D.; Yang, Z.; Isaacson, S. A.; Allard, J.; van der Merwe, P. A.; Gaus, K.; Dustin, M.; Dushek, O.

10.1101/2020.02.12.945170 — immunology — Posted on 2020-02-13

2269 Therapeutic Communication Skills Training: An Effective Tool to Improve the Caring Behaviors of ICU Nurses

Foroughameri, G.; Zare, F.; Farokhzadian, J.; Nematollahi, M.; Miri, S.

10.1101/2020.02.12.945394 — scientific communication and education — Posted on 2020-02-12

2270 Genetic conditionality of strength by the ACE gene in women horse riders

Majchrowicz, L.

10.1101/2020.02.12.945444 — physiology — Posted on 2020-02-12

2271 Antagonistic roles of NOT1 paralogues in the timing of gene expression in Plasmodium falciparum

Liu, Y.; Rai, R.; Lei, Z.; Zhang, C.; Rocamora, F.; Featherstone, M.; Bozdech, Z.

10.1101/2020.02.12.945477 — molecular biology — Posted on 2020-02-12

2272 The PINK1 - Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells

Bradshaw, A. V.; Campbell, P.; Schapira, A. H. V.; Morris, H. R.; Taanman, J.-W.

10.1101/2020.02.12.945469 — cell biology — Posted on 2020-02-12

2273 Mitochondrial event localiser (MEL) to quantitatively describe fission, fusion and depolarisation in the three-dimensional space

Theart, R. P.; Kriel, J.; Loos, B.; Niesler, T.

10.1101/2020.02.12.945451 — bioinformatics — Posted on 2020-02-12

2274 Incidence of atrial septal defects in children attended the Cardiac Center of Ethiopia during January 2016 to December 2018

Afework, M.; Musa, A. H.; Bedru, M.; Tamirat, S.

10.1101/2020.02.12.945360 — developmental biology — Posted on 2020-02-12

2275 Computational Modeling of Anisotropic Fatigue Behavior of Cancellous Bone under Uniaxial and Multiaxial Loading

Januddi, F.; Harun, M. N.; Abdullah, J.; Mostakhdemin, M.; Syahrom, A.

10.1101/2020.02.12.945352 — bioengineering — Posted on 2020-02-12

2276 In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

Anderson, S. D.; Tabassum, A.; Yeon, J. K.; Sharma, G.; Santos, P.; Soong, T. H.; Thu, Y. W.; Nies, I.; Kurita, T.; Chandler, A.; Alsamarah, A.; Kanassatega, R.-S.; Luo, Y.; Botello-Smith, W. M.; Andresen, B. T.

10.1101/2020.02.12.945402 — pharmacology and toxicology — Posted on 2020-02-12

2277 A critical period terminates the differentiation of olfactory sensory neurons

Jafari, S.; Alenius, M.

10.1101/2020.02.12.945428 — neuroscience — Posted on 2020-02-12

2278 Temporal and genetic variation in female aggression after mating

Bath, E.; Biscocho, E. R.; Easton-Calabria, A.; Wigby, S.

10.1101/2020.02.12.945436 — animal behavior and cognition — Posted on 2020-02-12

2279 A screening of the MMV Pathogen Box(R) reveals new potential antifungal drugs against the etiologic agents of chromoblastomycosis

Coelho, R.; Joffe, L. S.; Alves, G. M.; Figueiredo-Carvalho, M. H. G.; Brito-Santos, F.; Amaral, A. C. F.; Rodrigues, M. L.; Almeida-Paes, R.

10.1101/2020.02.12.945378 — microbiology — Posted on 2020-02-12

2280 Common Vetch: a drought tolerant, high protein neglected leguminous crop with potential as a sustainable food source.

Nguyen, V.; Riley, S.; Nagel, S.; Fisk, I.; Searle, I. R.

10.1101/2020.02.11.943324 — plant biology — Posted on 2020-02-12

2281 A Cretaceous bug indicates that exaggerated antennae may be a double-edged sword in evolution

Du, B.-J.; Chen, R.; Tao, W.-T.; Shi, H.-L.; Bu, W.-J.; Liu, Y.; Ma, S.; Ni, M.-Y.; Kong, F.-L.; Xiao, J.-H.; Huang, D.-W.

10.1101/2020.02.11.942920 — paleontology — Posted on 2020-02-12

2282 Emergence of stealth polymorphs that escape α-synuclein amyloid monitoring, take over and acutely spread in neurons

De Giorgi, F.; Laferriere, F.; Zinghirino, F.; Faggiani, E.; Lends, A.; Bertoni, M.; Yu, X.; Grelard, A.; Morvan, E.; Habenstein, B.; Dutheil, N.; Doudnikoff, E.; Daniel, J.; Claverol, S.; Qin, C.; Loquet, A.; Bezard, E.; Ichas, F.

10.1101/2020.02.11.943670 — neuroscience — Posted on 2020-02-12

2283 Integration of Brain and Behavior Measures for Identification of Data-Driven Groups Cutting Across Children with ASD, ADHD, or OCD

Jacobs, G. R.; Voineskos, A. N.; Hawco, C.; Stefanik, L.; Forde, N. J.; Dickie, E.; Lai, M.-C.; Szatmari, P.; Schachar, R. J.; Crosbie, J.; Arnold, P.; Goldenberg, A.; Erdman, L.; Lerch, J.; Anagnostou, E.; Ameis, S. H.

10.1101/2020.02.11.944744 — neuroscience — Posted on 2020-02-12

2284 A versatile and modular tetrode-based device for single-unit recordings in rodent ex vivo and in vivo acute preparations

Machado, F.; Sousa, N.; Monteiro, P.; Jacinto, L.

10.1101/2020.02.11.940809 — neuroscience — Posted on 2020-02-12

2285 Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults

Trelle, A. N.; Carr, V. A.; Guerin, S. A.; Thieu, M. K.; Jayakumar, M.; Guo, W.; Nadiadwala, A.; Corso, N. K.; Hunt, M. P.; Litovsky, C. P.; Tanner, N. J.; Deutsch, G. K.; Bernstein, J. D.; Harrison, M. B.; Khazenzon, A. M.; Jiang, J.; Sha, S. J.; Fredericks, C. A.; Rutt, B. K.; Mormino, E. C.; Kerchner, G. A.; Wagner, A. D.

10.1101/2020.02.11.940668 — neuroscience — Posted on 2020-02-12

2286 Distinct striatal subregions and corticostriatal connectivity for effort, action and reward

Suzuki, S.; Lawlor, V. M.; Cooper, J. A.; Arulpragasam, A. R.; Treadway, M. T.

10.1101/2020.02.12.925313 — neuroscience — Posted on 2020-02-12

2287 Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks

Kim, R.; Sejnowski, T. J.

10.1101/2020.02.11.944751 — neuroscience — Posted on 2020-02-12

2288 V. longisporum elicits media-dependent secretome responses with a further capacity to distinguish between plant-related environments

Leonard, M.; Kuehn, A.; Harting, R.; Maurus, I.; Nagel, A.; Starke, J.; Kusch, H.; Valerius, O.; Feussner, K.; Feussner, I. H.; Kaever, A.; Landesfeind, M.; Morgenstern, B.; Becher, D.; Hecker, M.; Braus-Stromeyer, S. A.; Kronstad, J. W.; Braus, G. H.

10.1101/2020.02.11.943803 — genetics — Posted on 2020-02-12

2289 How to read a baby's mind: Re-imagining fMRI for awake, behaving infants

Ellis, C. T.; Skalaban, L. J.; Yates, T. S.; Bejjanki, V. R.; Cordova, N. I.; Turk-Browne, N. B.

10.1101/2020.02.11.944868 — neuroscience — Posted on 2020-02-12

2290 Epigenomic translocation of H3K4me3 broad domains following super-enhancer hijacking

Mikulasova, A.; Trevisan-Herraz, M.; Fung, K.; Ashby, C.; Karataraki, N.; Morgan, G. J.; Corcoran, A.; Hambleton, S.; Walker, B. A.; Rico, D.; Russell, L. J.

10.1101/2020.02.12.938563 — genomics — Posted on 2020-02-12

2291 Use of Bioelectric Impedance Analysis (BIA) as a new method to detect prostate cancer

Bartoletti, R.; Greco, A.; Di Vico, T.; Durante, J.; Ficarra, V.; Scilingo, E. P.; Valenza, G.

10.1101/2020.02.12.943829 — biophysics — Posted on 2020-02-12

2292 Disentangled behavioral representations

Dezfouli, A.; Ashtiani, H.; Ghattas, O.; Nock, R.; Dayan, P.; Ong, C. S.

10.1101/658252 — bioinformatics — Posted on 2020-02-12

2293 PHF3 regulates neuronal gene expression through the new Pol II CTD reader domain SPOC

Appel, L.-M.; Franke, V.; Bruno, M.; Grishkovskaya, I.; Kasiliauskaite, A.; Schoeberl, U. E.; Puchinger, M. G.; Kostrhon, S.; Beltzung, E.; Mechtler, K.; Lin, G.; Vlasova, A.; Leeb, M.; Pavri, R.; Stark, A.; Akalin, A.; Stefl, R.; Bernecky, C.; Djinovic-Carugo, K.; Slade, D.

10.1101/2020.02.11.943159 — biochemistry — Posted on 2020-02-12

2294 Codon-usage optimization in the prokaryotic tree of life: How synonymous codons are differentially selected in sequence domains with different expression levels and degrees of conservation.

Lopez, J. L.; Lozano, M. J.; Fabre, M. L.; Lagares, A.

10.1101/2020.02.12.942524 — microbiology — Posted on 2020-02-12

2295 Trait-based aerial dispersal of arbuscular mycorrhizal fungi

Chaudhary, B.; Nolimal, S.; Sosa Hernandez, M. A.; Egan, C.; Kastens, J.

10.1101/2020.02.12.943878 — ecology — Posted on 2020-02-12

2296 One New Species of the Genus Dryomys (Rodentia, Glirgae) from Xinjiang China, Dryomys Yarkandensis sp. nov

Liao, L.; An, R.; Shi, S.; Xu, Y.; Luo, Y.; Liao, W.

10.1101/2020.02.11.943381 — zoology — Posted on 2020-02-12

2297 Identification of key proteins involved in stickleback environmental adaption with system-level analysis

Hall, M.; Küeltz, D.; Almaas, E.

10.1101/2020.02.11.943522 — systems biology — Posted on 2020-02-12

2298 Tough Hydrogel-Based Biocontainment of Engineered Organisms for Continuous, Self-Powered Sensing and Computation

Tang, T.-C.; Tham, E.; Liu, X.; Yehl, K.; Rovner, A. J.; Yuk, H.; Isaacs, F. J.; Zhao, X.; Lu, T. K.

10.1101/2020.02.11.941120 — synthetic biology — Posted on 2020-02-12

2299 The FUSED LEAVES1/ADHERENT1 Regulatory Module Is Required For Maize Cuticle Development And Organ Separation

Liu, X.; Bourgault, R.; Strable, J.; Galli, M.; Chen, Z.; Dong, J.; Molina, I.; Gallavotti, A.

10.1101/2020.02.11.943787 — plant biology — Posted on 2020-02-12

2300 Transcriptomic and Proteomic Analyses of a New Cytoplasmic Male Sterile Line with wild Gossypium bickii. Genetic Background

Zhao, H.; Wang, J.; Qu, Y.; Peng, R.; Magwanga, R. O.; Liu, F.; Huang, J.

10.1101/2020.02.11.943464 — plant biology — Posted on 2020-02-12

2301 The Lanata trichome mutation increases stomatal conductance and reduces leaf temperature in tomato

Gasparini, K.; Souto, A. C. R.; da Silva, M. F.; da Costa, L. C.; Martins, S. C. V.; Peres, L. E. P.; Figueiredo, C. R. F.; Zsogon, A.

10.1101/2020.02.11.943761 — plant biology — Posted on 2020-02-12

2302 Increases in ambient temperature progressively disassemble Arabidopsis phytochrome B from individual photobodies with distinct thermostabilities

Hahm, J.; Kim, K.; Qiu, Y.; Chen, M.

10.1101/2020.02.11.930990 — plant biology — Posted on 2020-02-12

2303 A series of dual-reporter vectors for ratiometric analysis of protein abundance in plants

Khosla, A.; Rodriguez-Furlan, C.; Kapoor, S.; Van Norman, J. M.; Nelson, D. C.

10.1101/2020.02.10.939363 — plant biology — Posted on 2020-02-12

2304 Cortical processing of chemosensory and hedonic features of taste in active licking mice.

Bouaichi, C. G.; Vincis, R.

10.1101/2020.02.11.923565 — neuroscience — Posted on 2020-02-12

2305 Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

Perrin, F.; Papadopoulos, N.; Opsomer, R.; Vadukul, D. M.; Vrancx, C.; Smith, S. O.; Vertommen, D.; Kienlen-Campard, P.; Constantinescu, S. N.

10.1101/2020.02.11.943480 — neuroscience — Posted on 2020-02-12

2306 TRPM4 conductances in thalamic reticular nucleus neurons generate persistent firing during slow oscillations

O'Malley, J. J.; Seibt, F.; Chin, J.; Beierlein, M.

10.1101/2020.02.11.943746 — neuroscience — Posted on 2020-02-12

2307 Blast-induced mild traumatic brain injury promotes comorbid stress responses elicited by environmental cues attending blast exposure

Schindler, A. G.; Terry, G. E.; Wolden-Hanson, T.; Cline, M.; Meabon, J. S.; Raskind, M. M.; Peskind, E. R.; Phillips, P. E.; Cook, D. G.

10.1101/2020.02.11.935718 — neuroscience — Posted on 2020-02-12

2308 Graph neural representational learning of RNA secondary structures for predicting RNA-protein interactions

Yan, Z.; Hamilton, W. L.; Blanchette, M. D.

10.1101/2020.02.11.931030 — molecular biology — Posted on 2020-02-12

2309 Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome

Hussain, S.-R. A.; Yalvac, M. E.; Khoo, B.; Eckardt, S.; McLaughlin, K. J.

10.1101/2020.02.11.944819 — molecular biology — Posted on 2020-02-12

2310 Operative and technical modifications to the Coriolis(R) μ air sampler that improve sample recovery and biosafety during microbiological air sampling

Rufino de Sousa, N.; Shen, L.; Silcott, D.; Call, C. J.; Rothfuchs, A. G.

10.1101/2020.02.11.943662 — microbiology — Posted on 2020-02-12

2311 The human small intestine comprises two subsets of regulatory Foxp3+ CD4 T cells with very different life span and functional properties.

Chauhan, S. K.; Casado, R. B.; Landsverk, O. J. B.; Jahnsen, J.; Horneland, R.; Yaqub, S.; Aandahl, E. M.; Lundin, K. E. A.; Baekkevold, E. S.; Jahnsen, F. L.

10.1101/2020.02.12.941369 — immunology — Posted on 2020-02-12

2312 Phytochemical screening and antimicrobial activities studies of Acacia nilotica fruit cover

Abdalla, A. A.; Mustafa, M. I.; Makhawi, A. M.

10.1101/2020.02.11.943456 — biochemistry — Posted on 2020-02-12

2313 Osprey: Open-Source Processing, Reconstruction & Estimation of Magnetic Resonance Spectroscopy Data

Oeltzschner, G.; Zoellner, H. J.; Hui, S. C. N.; Mikkelsen, M.; Saleh, M. G.; Tapper, S.; Edden, R. A. E.

10.1101/2020.02.12.944207 — biochemistry — Posted on 2020-02-12

2314 Oomycete metabolism is highly dynamic and reflects lifestyle adaptations

Rodenburg, S. Y. A.; de Ridder, D.; Govers, F.; Seidl, M. F.

10.1101/2020.02.12.941195 — evolutionary biology — Posted on 2020-02-12

2315 Benchmarking DNA Methylation Assays for Marine Invertebrates

Dixon, G.; Matz, M. V.

10.1101/2020.02.10.943092 — ecology — Posted on 2020-02-12

2316 Visual and semantic representations predict subsequent memory in perceptual and conceptual memory tests

Davis, S. W.; Geib, B.; Wing, E.; Wang, W.-C.; Hovhannisyan, M.; Monge, Z.; Cabeza, R.

10.1101/2020.02.11.944801 — neuroscience — Posted on 2020-02-12

2317 ADAR1 can drive Multiple Myeloma progression by acting both as an RNA editor of specific transcripts and as a DNA mutator of their cognate genes

Tasakis, R. N.; Lagana, A.; Stamkopoulou, D.; Melnekoff, D. T.; Nedumaran, P.; Leshchenko, V.; Pecori, R.; Parekh, S.; Papavasiliou, F. N.

10.1101/2020.02.11.943845 — genomics — Posted on 2020-02-12

2318 Ant guards influence the mating system of their plant hosts by altering pollinator behaviour

Villamil, N.; Boege, K.; Stone, G. N.

10.1101/2020.02.11.943431 — ecology — Posted on 2020-02-12

2319 MS-DIAL 4: accelerating lipidomics using an MS/MS, CCS, and retention time atlas

Tsugawa, H.; Ikeda, K.; Takahashi, M.; Satoh, A.; Mori, Y.; Uchino, H.; Okahashi, N.; Yamada, Y.; Tada, I.; Bonini, P.; Higashi, Y.; Okazaki, Y.; Zhou, Z.; Zhu, Z.-J.; Koelmel, J.; Cajka, T.; Fiehn, O.; Saito, K.; Arita, M.; Arita, M.

10.1101/2020.02.11.944900 — bioinformatics — Posted on 2020-02-12

2320 scTenifoldNet: a machine learning workflow for constructing and comparing transcriptome-wide gene regulatory networks from single-cell data

Osorio, D.; Zhong, Y.; Li, G.; Huang, J. Z.; Cai, J. J.

10.1101/2020.02.12.931469 — bioinformatics — Posted on 2020-02-12

2321 Large-scale sequence similarity analysis reveals the scope of sequence and function divergence in PilZ domain proteins

Cheang, Q. W.; Sheng, S.; Xu, L.; Liang, Z.-X.

10.1101/2020.02.11.943704 — biochemistry — Posted on 2020-02-12

2322 Forest decline differentially affects trophic guilds of canopy-dwelling beetles

Parmain, G.; Nusillard, B.; Pineau, X.; Brousse, R.; Fontaine-Guenel, T.; Ledet, R.; Vincent-Barbaroux, C.; Bouget, C.; Salle, A.

10.1101/2020.02.11.943753 — ecology — Posted on 2020-02-12

2323 Fibronectin-Based Nanomechanical Biosensors to Map 3D Strains in Live Cells and Tissues

Shiwarski, D. J.; Tashman, J. W.; Tsamis, A.; Bliley, J. M.; Blundon, M. A.; Aranda-Michel, E.; Jallerat, Q.; Szymanski, J. M.; McCartney, B. M.; Feinberg, A. W.

10.1101/2020.02.11.943696 — bioengineering — Posted on 2020-02-12

2324 Docosahexaenoic acid has stem cell-specific effects in the SVZ and restores olfactory neurogenesis and function in the aging brain

Le Belle, J.; Sperry, J.; Ludwig, K.; Harris, N.; Caldwell, M.; Kornblum, H.

10.1101/2020.02.10.942870 — neuroscience — Posted on 2020-02-12

2325 RiboTag-Seq Reveals a Compensatory cAMP Responsive Gene Network in Striatal Microglia induced by Morphine Withdrawal

Coffey, K. R.; Lesiak, A. J.; Marx, R. G.; Vo, E. K.; Garden, G. A.; Neumaier, J. F.

10.1101/2020.02.10.942953 — neuroscience — Posted on 2020-02-12

2326 Predicting brain function from anatomy using geometric deep learning

Ribeiro, F. L.; Bollmann, S.; Puckett, A. M.

10.1101/2020.02.11.934471 — neuroscience — Posted on 2020-02-12

2327 Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles

Huang, Y.; Cheng, L.; Turchinovich, A.; Mahairaki, V.; Troncoso, J. C.; Pletnikov, O.; Haughey, N. J.; Vella, L. J.; Hill, A.; Zheng, L.; Witwer, K. W.

10.1101/2020.02.10.940999 — neuroscience — Posted on 2020-02-12

2328 Differential activation of P-TEFb complexes in the development of cardiomyocyte hypertrophy following activation of distinct GPCRs

Martin, R. D.; Sun, Y.; MacKinnon, S.; Cuccia, L.; Page, V.; Hebert, T.; Tanny, J. C.

10.1101/2020.02.10.943209 — molecular biology — Posted on 2020-02-12

2329 Puf4 Mediates Post-transcriptional Regulation of Caspofungin Resistance in Cryptococcus neoformans

Kalem, M. C.; Subbiah, H.; Leipheimer, J.; Glazier, V. E.; Panepinto, J. C.

10.1101/2020.02.10.943191 — microbiology — Posted on 2020-02-12

2330 Telacebec for ultra-short treatment of Buruli ulcer in a mouse model

Almeida, D.; Converse, P. J.; Omansen, T. F.; TYAGI, S.; Tasneen, R.; kim, J.; Nuermberger, E.

10.1101/2020.02.10.943175 — microbiology — Posted on 2020-02-12

2331 A Comprehensive Survey of Genomic Mutations in Breast Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets

Liu, S.; Chen, C.; Zhang, X.

10.1101/2020.02.11.943258 — genomics — Posted on 2020-02-12

2332 Drivers of vascular plant species area relationships in British broadleaved woodlands and their effects on the species area curve

Guy, P.; Prentice, I. C.; Smart, S.

10.1101/2020.02.11.943282 — ecology — Posted on 2020-02-12

2333 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.

Wells, J. N.; Buschauer, R.; Mackens-Kiani, T.; Best, K.; Kratzat, H.; Berninghausen, O.; Becker, T.; Gilbert, W. V.; Cheng, J.; Beckmann, R.

10.1101/2020.02.12.944066 — molecular biology — Posted on 2020-02-12

2334 Demonstration of resistance to satyrization behavior in Aedes aegypti (Linnaeus) from La Reunion island

Maiga, H.; Gilles, J. R. L.; Lees, R. S.; Yamada, H.; Bouyer, J.

10.1101/2020.02.10.942839 — ecology — Posted on 2020-02-12

2335 Profiling the immune vulnerability landscape of the 2019 Novel Coronavirus

Zhu, J.; Kim, J.; Xiao, X.; Wang, Y.; Luo, D.; Chen, R.; Xu, L.; Zhang, H.; Xiao, G.; Zhan, X.; Wang, T.; Xie, Y.

10.1101/2020.02.08.939553 — bioinformatics — Posted on 2020-02-12

2336 Individual-subject functional localization increases univariate activation but not multivariate pattern discriminability in the 'multiple-demand' frontoparietal network

Shashidhara, S.; Spronkers, F. S.; Erez, Y.

10.1101/661934 — neuroscience — Posted on 2020-02-12

2337 AFM characterization of the interaction of PriA helicase with stalled DNA replication forks

Wang, Y.; Sun, Z.; Bianco, P. R.; Lyubchenko, Y. L.

10.1101/2020.02.12.945972 — biophysics — Posted on 2020-02-12

2338 CELL ATLAS OF THE HUMAN FOVEA AND PERIPHERAL RETINA

Yan, W.; Peng, Y.-R.; van Zyl, T.; Regev, A.; Shekhar, K.; Juric, D.; Sanes, J.

10.1101/2020.02.11.943779 — neuroscience — Posted on 2020-02-12

2339 Myosin 18Aα targets guanine nucleotide exchange factor β-Pix to dendritic spines of cerebellar Purkinje neurons to promote spine maturation

Alexander, C. J.; Barzik, M.; Fujiwara, I.; Remmert, K.; Wang, Y.-X.; Petralia, R. S.; Friedman, T. B.; Hammer, J. A.

10.1101/2020.02.12.944488 — neuroscience — Posted on 2020-02-12

2340 Mitochondria regulate Drosophila intestinal stem cell differentiation through FOXO

Zhang, F.; Pirooznia, M.; Xu, H.

10.1101/2020.02.12.946194 — developmental biology — Posted on 2020-02-12

2341 Nanoscale Molecular Characterisation of Hair Cuticles using Integrated AFM-IR

Fellows, A. P.; Casford, M. T. L.; Davies, P. B.

10.1101/2020.02.12.946103 — biophysics — Posted on 2020-02-12

2342 Stem cell lineage survival as a noisy competition for niche access

Corominas-Murtra, B.; Scheele, C. L. G. J.; Kishi, K.; Ellenbroek, S. I. J.; Simons, B. D.; van Rheenen, J.; Hannezo, E.

10.1101/2020.02.12.945253 — biophysics — Posted on 2020-02-12

2343 Fgf4 is critical for maintaining Hes7 levels and Notch oscillations in the somite segmentation clock

Lewandoski, M.; Anderson, M. J.; Magidson, V.; Kageyama, R.

10.1101/2020.02.12.945931 — developmental biology — Posted on 2020-02-12

2344 Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis

Riching, A. S.; Danis, E.; Zhao, Y.; Cao, Y.; Chi, C.; Bagchi, R.; Klein, B.; Xu, H.; Kutateladze, T.; McKinsey, T.; Buttrick, P.; Song, K.

10.1101/2020.02.12.945790 — cell biology — Posted on 2020-02-12

2345 corto: a lightweight R package for Gene NetworkInference and Master Regulator Analysis

Mercatelli, D.; Lopez-Garcia, G.; Giorgi, F. M.

10.1101/2020.02.10.942623 — bioinformatics — Posted on 2020-02-12

2346 Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies

Ahmed, S. F.; Quadeer, A. A.; McKay, M. R.

10.1101/2020.02.03.933226 — bioinformatics — Posted on 2020-02-12

2347 Association Study of Over 200,000 Subjects Detects Novel Rare Variants, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

Emami, N. C.; Cavazos, T. B.; Rashkin, S. R.; Cario, C. L.; Graff, R. E.; Tai, C. G.; Mefford, J. A.; Kachuri, L.; Wan, E.; Wong, S.; Aaronson, D. S.; Presti, J.; Habel, L. A.; Shan, J.; Ranatunga, D. K.; Chao, C. R.; Ghai, N. R.; Jorgenson, E.; Sakoda, L. C.; Kvale, M. N.; Kwok, P.-Y.; Schaefer, C.; Risch, N.; Hoffmann, T. J.; Van Den Eeden, S. K.; Witte, J. S.

10.1101/2020.02.12.929463 — genomics — Posted on 2020-02-12

2348 A footptrint of plant eco-geographic adaptation on the composition of the barley rhizosphere bacterial microbiota

Alegria Terrazas, R.; Balbirnie-Cumming, K.; Morris, J.; Hedley, P.; Russell, J.; Paterson, E.; Baggs, E.; Bulgarelli, D.

10.1101/2020.02.11.944140 — plant biology — Posted on 2020-02-12

2349 Respiratory syncytial virus sequesters NF-κB subunit p65 to cytoplasmic inclusion bodies to inhibit innate immune signalling

Jobe, F.; Simpson, J.; Hawes, P.; Guzman, E.; Bailey, D.

10.1101/2020.02.11.944363 — microbiology — Posted on 2020-02-12

2350 Duplex real-time PCR assay for the simultaneous detection of Achromobacter xylosoxidans and Achromobacter spp.

Price, E. P.; Soler Arango, V.; Kidd, T. J.; Fraser, T. A.; Nguyen, T.-K.; Bell, S. C.; Sarovich, D. S.

10.1101/2020.02.11.944942 — microbiology — Posted on 2020-02-12

2351 The Pebble/Rho1/Anillin pathway controls polyploidization and axonal wrapping activity in the glial cells of the Drosophila eye

Tavares, L.; Gracio, P.; Ramos, R.; Traquete, R.; Relvas, J. B.; Pereira, P. S.

10.1101/2020.02.12.945600 — developmental biology — Posted on 2020-02-12

2352 A pyro-phosphodegron controls MYC polyubiquitination to regulate cell survival

Lolla, P.; Shah, A.; C.P., U.; Oddi, V.; Bhandari, R.

10.1101/2020.02.12.945634 — cell biology — Posted on 2020-02-12

2353 Molecular control of interfacial protein structure on graphene-based substrates steers cell fate

Kumar, S.; Parekh, S. H.

10.1101/2020.02.11.944678 — bioengineering — Posted on 2020-02-12

2354 IGF-I Governs Cortical Inhibitory Synaptic Plasticity By Astrocyte Activation

Noriega-Prieto, J. A.; Maglio, L. E.; Zegarra-Valdivia, J.; Pignatelli, J.; Fernandez, A. M.; Martinez-Rachadell, L.; Fernandes, J.; Nunez, A.; Araque, A.; Torres-Aleman, I.; Fernandez de Sevilla, D.

10.1101/2020.02.11.942532 — neuroscience — Posted on 2020-02-12

2355 Paladin is a PI(4,5)P2 phosphoinositide phosphatase that regulates endosomal signaling and angiogenesis

Nitzsche, A.; Pietila, R.; Testini, C.; Ninchoji, T.; Smith, R. O.; Ekvarn, E.; Larsson, J.; Roche, F. P.; Egana, I.; Jauhiainen, S.; Berger, P.; Claesson-Welsh, L.; Hellstrom, M.

10.1101/2020.02.11.943183 — cell biology — Posted on 2020-02-12

2356 Cryopreservation of midbrain dopaminergic neural cells differentiated from human embryonic stem cells

Drummond, N. J.; Dolt, K. S.; Canham, M. A.; Kilbride, P.; Morris, G. J.; Kunath, T.

10.1101/2020.02.11.944272 — cell biology — Posted on 2020-02-12

2357 Amyloid fibril structure of islet amyloid polypeptide by cryo-electron microscopy reveals similarities with amyloid beta

Roeder, C.; Kupreichyk, T.; Gremer, L.; Schaefer, L. U.; Pothula, K. R.; Ravelli, R. B.; Willbold, D.; Hoyer, W.; Schroeder, G. F.

10.1101/2020.02.11.944546 — biochemistry — Posted on 2020-02-12

2358 Interneuronal mechanisms underlying a learning-induced switch in a sensory response that anticipates changes in behavioural outcomes

Pirger, Z.; Laszlo, Z.; Naskar, S.; O'Shea, M.; Benjamin, P. R.; Kemenes, G.; Kemenes, I.

10.1101/2020.02.12.944553 — neuroscience — Posted on 2020-02-12

2359 Presynaptic inhibition rapidly stabilises recurrent excitation in the face of plasticity

Naumann, L. B.; Sprekeler, H.

10.1101/2020.02.11.944082 — neuroscience — Posted on 2020-02-12

2360 Multimodal finger-printing of the human precentral cortex forming the motor hand knob

Dubbioso, R.; Madsen, K. H.; Thielscher, A.; Siebner, H. R.

10.1101/2020.02.11.942771 — neuroscience — Posted on 2020-02-12

2361 Next-generation cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity

Yu, Y.; Leete, T.; Born, D. A.; Young, L.; Barrera, L. A.; Lee, S.-J.; Rees, H. A.; Ciaramella, G.; Gaudelli, N. M.

10.1101/2020.02.11.944165 — genomics — Posted on 2020-02-12

2362 Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae

Prada-Luengo, I.; Moller, H. D.; Henriksen, R. A.; Gao, Q.; Larsen, C. E.; Alizadeh, S.; Maretty, L.; Houseley, J.; Regenberg, B.

10.1101/2020.02.11.943357 — cell biology — Posted on 2020-02-12

2363 Integrating multimodal data sets into a mathematical framework to describe and predict therapeutic resistance in cancer

Johnson, K. E.; Howard, G. R.; Morgan, D.; Brenner, E.; Gardner, A. L.; Durrett, R. E.; Mo, W.; Al'Khafaji, A. M.; Sontag, E.; Jarrett, A. M.; Yankeelov, T. E.; Brock, A.

10.1101/2020.02.11.943738 — cancer biology — Posted on 2020-02-12

2364 Untangling biological factors influencing trajectory inference from single cell data

Charrout, M.; Reinders, M.; Mahfouz, A.

10.1101/2020.02.11.942102 — bioinformatics — Posted on 2020-02-12

2365 Single-Cell Analysis of the 3D Topologies of Genomic Loci Using Genome Architecture Mapping

Welch, L. R.; Baugher, C.; Zhang, Y.; Davis, T.; Marzluff, W. F.; Welch, J. D.; Pombo, A.

10.1101/2020.02.10.941047 — bioinformatics — Posted on 2020-02-12

2366 The Seminavis robusta genome provides insights into the evolutionary adaptations of benthic diatoms

Osuna-Cruz, C. M.; Bilcke, G.; Vancaester, E.; De Decker, S.; Poulsen, N.; Bulankova, P.; Verhelst, B.; Audoor, S.; Stojanovova, D.; Pargana, A.; Russo, M.; Stock, F.; Cirri, E.; Brembu, T.; Pohnert, G.; Winge, P.; Bones, A. M.; Piganeu, G.; Ferrante, M. I.; Mock, T.; Sterck, L.; Sabbe, K.; De Veylder, L.; Vyverman, W.; Vandepoele, K.

10.1101/2020.02.11.942037 — bioinformatics — Posted on 2020-02-12

2367 Longitudinal analysis of naturally acquired antibodies to PfEMP1 CIDR domain variants and their association with malaria protection

10.1101/2020.02.11.944330 — immunology — Posted on 2020-02-12

2368 Varying thermal exposure, host-plant traits and oviposition behaviour across vegetation ecotones

Vives-Ingla, M.; Sala-Garcia, J.; Stefanescu, C.; Penuelas, J.; Carnicer, J.

10.1101/2020.02.11.944439 — ecology — Posted on 2020-02-12

2369 Myc supercompetitor cells exploit the NMDA receptor to subdue their wild-type neighbours via cell competition

Banreti, A. R.; Meier, P.

10.1101/2020.02.11.943498 — cell biology — Posted on 2020-02-12

2370 Selection driven tumor evolution involving non-cell autonomous environmental engineering leads to patterns of clonal expansion consistent with neutral evolution

Edwards, J. T.; Marusyk, A. T.; Basanta, D.

10.1101/2020.02.11.944843 — cancer biology — Posted on 2020-02-12

2371 Altered hippocampal place cell representation and theta rhythmicity following moderate prenatal alcohol exposure

Harvey, R. E.; Berkowitz, L. E.; Savage, D. D.; Hamilton, D. A.; Clark, B. J.

10.1101/2020.02.11.944173 — neuroscience — Posted on 2020-02-12

2372 A Casz1 - NuRD complex regulates temporal identity transitions in neural progenitors

Mattar, P.; Jolicoeur, C.; Shah, S.; Cayouette, M.

10.1101/2020.02.11.944470 — developmental biology — Posted on 2020-02-12

2373 Microtubule attachment and centromeric tension shape the protein architecture of the human kinetochore

Joglekar, A.; Kukreja, A. A.; Kavuri, S.

10.1101/2020.02.11.944694 — cell biology — Posted on 2020-02-12

2374 Platelet TSP-1 Controls Prostate Cancer-Induced Osteoclast Differentiation and Bone Marrow-Derived Cell Mobilization through TGFβ-1

Kerr, B. A.; Harris, K. S.; Shi, L.; Willey, J. S.; Soto-Pantoja, D. R.; Byzova, T. V.

10.1101/2020.02.11.943860 — cancer biology — Posted on 2020-02-12

2375 Harnessing tumor immune ecosystem dynamics to personalize radiotherapy

Grass, G. D.; Lopez Alfonso, J. C.; Welsh, E. A.; Ahmed, K.; Teer, J.; Harrison, L. B.; Cleveland, J.; Mule, J.; Eschrich, S.; Enderling, H.; Torres Roca, J.

10.1101/2020.02.11.944512 — cancer biology — Posted on 2020-02-12

2376 Characterizing the tumor microenvironment of metastatic ovarian cancer by single cell transcriptomics

Olalekan, S.; Xie, B.; Back, R.; Eckart, H.; Basu, A.

10.1101/2020.02.11.944561 — cancer biology — Posted on 2020-02-12

2377 Design and fabrication of recombinant reflectin-based Bragg reflectors: bio-design engineering and photoisomerism induced wavelength modulation

Wolde-Michael, E.; Roberts, A. D.; Heyes, D. J.; Dumanli, A.; Blaker, J.; Takano, E.; Scrutton, N.

10.1101/2020.02.11.942110 — synthetic biology — Posted on 2020-02-12

2378 The Landscape of Mutational Mosaicism in Autistic and Normal Human Cerebral Cortex

Rodin, R. E.; Dou, Y.; Kwon, M.; Sherman, M. A.; D'Gama, A. M.; Doan, R. N.; Rento, L. M.; Girskis, K. M.; Bohrson, C. L.; Kim, S. N.; Luquette, L. J.; Gulhan, D. C.; Brain Somatic Mosaicism Network, ; Park, P. J.; Walsh, C. A.

10.1101/2020.02.11.944413 — neuroscience — Posted on 2020-02-12

2379 The chloroplast ribonucleoprotein CP33B quantitatively binds the psbA mRNA

Teubner, M.; Lenzen, B.; Espenberger, L. B.; Fuss, J.; Nickelsen, J.; Krause, K.; Ruwe, H.; Schmitz-Linneweber, C.

10.1101/2020.02.11.944249 — molecular biology — Posted on 2020-02-12

2380 Rapid and Efficient Co-Transcriptional Splicing Enhances Mammalian Gene Expression

Reimer, K. A.; Mimoso, C.; Adelman, K.; Neugebauer, K. M.

10.1101/2020.02.11.944595 — molecular biology — Posted on 2020-02-12

2381 Intron retention as a new marker of the pre-disease state and its recovery to the normal state by a traditional Japanese multi-herbal medicine

Okada, N.; Oshima, K.; Iwasaki, Y.; Maruko, A.; Iioka, E.; Vu, T.-D.; Fujitsuka, N.; Nishi, A.; Sugiyama, A.; Nishiyama, M.; Kaneko, A.; Yamamoto, M.; Nishimura, S.

10.1101/2020.02.10.941435 — molecular biology — Posted on 2020-02-12

2382 Adhesivity and motility of a zoonotic spirochete: Implications in host-dependent pathogenicity

Xu, J.; Koizumi, N.; Nakamura, S.

10.1101/2020.02.11.944587 — microbiology — Posted on 2020-02-12

2383 A population-level invasion by transposable elements in a fungal pathogen

Oggenfuss, U.; Badet, T.; Wicker, T.; Hartmann, F. E.; Kumar Singh, N.; Abraham, L. N.; Karisto, P.; Vonlanthen, T.; Mundt, C. C.; McDonald, B. A.; Croll, D.

10.1101/2020.02.11.944652 — genomics — Posted on 2020-02-12

2384 Is genetic liability to ADHD and ASD causally linked to educational attainment?

Dardani, C.; Leppert, B.; Riglin, L.; Rai, D.; Howe, L. D.; Smith, G. D.; Tilling, K.; Thapar, A.; Davies, N. M.; Anderson, E. L.; Stergiakouli, E. L.

10.1101/2020.02.11.944041 — genetics — Posted on 2020-02-12

2385 Assessment of Operant Learning and Memory in Mice Born through Intracytoplasmic Sperm Injection

Lewon, M.; Wang, Y.; Peters, C. M.; Peterson, M.; Zheng, H.; Hayes, L. J.; Yan, W.

10.1101/2020.02.11.942235 — genetics — Posted on 2020-02-12

2386 Increasing Chlorophyll a Amid Stable Nutrient Concentrations in Rhode Island Lakes and Reservoirs

Hollister, J. W.; Kellog, D. Q.; Kreakie, B. J.; Shivers, S. S.; Milstead, W. B.; Herron, E.; Green, L.; Gold, A. J.

10.1101/2020.02.11.944280 — ecology — Posted on 2020-02-12

2387 Cadherin clustering controls heterogeneous, asymmetric junction dynamics during vertebrate axis elongation

Huebner, R.; Malmi-Kakkada, A. N.; Sarikaya, S.; Weng, S.; Thirumalai, D.; Wallingford, J. B.

10.1101/2020.02.11.944033 — cell biology — Posted on 2020-02-12

2388 Kupffer Cell Release of Platelet Activating Factor Drives Dose Limiting Toxicities of Nucleic Acid Nanocarriers

Jackson, M. A.; Patel, S. S.; Yu, F.; Cottam, M. A.; Glass, E. B.; Dollinger, B. R.; Hoogenboezem, E. N.; Patil, P.; Liu, D. D.; Kelly, I. B.; Bedingfield, S. K.; King, A. R.; Miles, R. E.; Hasty, A. M.; Giorgio, T. D.; Duvall, C. L.

10.1101/2020.02.11.944504 — bioengineering — Posted on 2020-02-12

2389 Design trade-offs and robust architectures for combined transcriptional and translational resource allocation controllers

Darlington, A. P. S.; Bates, D. G.

10.1101/2020.02.11.944215 — synthetic biology — Posted on 2020-02-12

2390 Birds versus bats: attack strategies of bat-hunting hawks, and the dilution effect of swarming

Brighton, C.; Zusi, L.; McGowan, K.; Kinniry, M.; Kloepper, L.; Taylor, G. K.

10.1101/2020.02.11.942060 — animal behavior and cognition — Posted on 2020-02-12

2391 General Framework for Tracking Neural Activity Over Long-Term Extracellular Recordings

Chaure, F. J.; Rey, H. G.

10.1101/2020.02.11.944686 — neuroscience — Posted on 2020-02-12

2392 How does group differences in motion scrubbing affect false positives in functional connectivity studies?

Eklund, A.; Nichols, T.; Afyouni, S.; Craddock, C.

10.1101/2020.02.12.944454 — neuroscience — Posted on 2020-02-12

2393 Classifyber, a robust streamline-based linear classifier for white matter bundle segmentation

Berto, G.; Bullock, D.; Astolfi, P.; Hayashi, S.; Zigiotto, L.; Annicchiarico, L.; Corsini, F.; De Benedictis, A.; Sarubbo, S.; Pestilli, F.; Avesani, P.; Olivetti, E.

10.1101/2020.02.10.942714 — neuroscience — Posted on 2020-02-12

2394 The Predictive Global Neuronal Workspace: A Formal Active Inference Model of Visual Consciousness

Whyte, C. J.; Smith, R.

10.1101/2020.02.11.944611 — neuroscience — Posted on 2020-02-12

2395 Replication protein A binds RNA and promotes R-loop formation

Mazina, O. M.; Somarowthu, S.; Kadyrova, L. Y.; Baranovskiy, A. G.; Tahirov, T. H.; Kadyrov, F. A.; Mazin, A. V.

10.1101/2020.02.11.943977 — molecular biology — Posted on 2020-02-12

2396 Excessive O-GlcNAcylation causes heart failure and sudden death

Umapathi, P.; Banerjee, P.; Zachara, N. E.; Abrol, N.; Wang, Q.; Mesubi, O. O.; Luczak, E. D.; Wu, Y.; Granger, J. M.; Wei, A.-C.; Reyes Gaido, O. E.; Florea, L. D.; Talbot, C. C.; Hart, G. W.; Anderson, M. E.

10.1101/2020.02.11.943910 — molecular biology — Posted on 2020-02-12

2397 A Generalized Discrete Dynamic Model for Human Epidemics

Zhang, W.; Chen, Z.; Lu, Y.; Guo, Z.; Qi, Y.; Wang, G.; Lu, J.

10.1101/2020.02.11.944728 — microbiology — Posted on 2020-02-12

2398 Combination of antifungal drugs and protease inhibitors prevent Candida albicans biofilm formation and disrupt mature biofilms

Lohse, M. B.; Gulati, M.; Craik, C. S.; JOHNSON, A. D.; Nobile, C. J.

10.1101/2020.02.11.945030 — microbiology — Posted on 2020-02-12

2399 Antiviral and Virucidal activities of sulphated polysaccharides against Japanese Encephalitis Virus.

Rothan, H. A.

10.1101/2020.02.11.944116 — microbiology — Posted on 2020-02-12

2400 Massively Parallel Analysis of Human 3' UTRs Reveals that AU-Rich Element Length and Registration Predict mRNA Destabilization

Siegel, D. A.; Le Tonqueze, O.; Biton, A.; Zaitlen, N.; Erle, D. J.

10.1101/2020.02.12.945063 — genomics — Posted on 2020-02-12

2401 Transcriptional profiling of Multiple System Atrophy cerebellar tissue highlights differences between the parkinsonian and cerebellar sub-types of the disease

Piras, I.; Bleul, C.; Schrauwen, I.; Talboom, J.; Llaci, L.; De Both, M.; Naymik, M.; Halliday, G.; Bettencourt, C.; Holton, J.; Serrano, G.; Sue, L.; Beach, T.; Stefanova, N.; Huentelman, M.

10.1101/2020.02.11.944306 — genomics — Posted on 2020-02-12

2402 Identifying states of collateral sensitivity during the evolution of therapeutic resistance in Ewings sarcoma

Scarborough, J. A.; McClure, E.; Anderson, P.; Dhawan, A.; Durmaz, A.; Lessnick, S. L.; Hitomi, M.; Scott, J. G.

10.1101/2020.02.11.943936 — evolutionary biology — Posted on 2020-02-12

2403 How many bird and mammal extinctions has recent conservation action prevented?

Bolam, F. C.; Mair, L.; Angelico, M.; Brooks, T. M.; Burgman, M.; Hermes, C.; Hoffmann, M.; Martin, R. W.; McGowan, P. J. K.; Rodrigues, A. S. L.; Rondinini, C.; Wheatley, H.; Bedolla-Guzman, Y.; Calzada, J.; Child, M. F.; Cranswick, P. A.; Dickman, C. R.; Fessl, B.; Fisher, D. O.; Garnett, S. T.; Groombridge, J. J.; Johnson, C. N.; Kennerley, R. J.; King, S. R. B.; Lamoreux, J. F.; Lees, A. C.; Lens, L.; Mahood, S. P.; Mallon, D. P.; Meijaard, E.; Mendez-Sanchez, F.; Percequillo, A. R.; Regan, T. J.; Renjifo, L. M.; Rivers, M. C.; Roach, N. S.; Roxburgh, L.; Safford, R. J.; Salaman, P.; Squir

10.1101/2020.02.11.943902 — ecology — Posted on 2020-02-12

2404 The Physical Structure and Behavior of the California Current System

Renault, L.; McWilliams, J. C.; Jousse, A.; Deutsch, C. A.; Frenzel, H.; Kessouri, F.; Chen, R.

10.1101/2020.02.10.942730 — ecology — Posted on 2020-02-12

2405 Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues

Kastan, N.; Gnedeva, K.; Alisch, T.; Petelski, A.; Huggins, D.; Chiaravalli, J.; Aharanov, A.; Shakked, A.; Tzahor, E.; Nagiel, A.; Segil, N.; Hudspeth, A. J.

10.1101/2020.02.11.944157 — developmental biology — Posted on 2020-02-12

2406 Selective LXR agonist, DMHCA, corrects the retina-bone marrow axis in type 2 diabetes

Vieira, C. P.; Fortmann, S. D.; Hossain, M.; Longhini, A. L.; Hammer, S. S.; Asare-Bediako, B.; Crossman, D. K.; Sielski, M. S.; Adu-Agyeiwaah, Y.; Dupont, M.; Floyd, J. L.; Li Calzi, S.; Lydic, T.; Welner, R. S.; Blanchard, G. J.; Busik, J. V.; Grant, M. B.

10.1101/2020.02.11.942292 — cell biology — Posted on 2020-02-12

2407 Bile acid composition regulates the manganese transporter Slc30a10 in intestine

Ahmad, T. R.; Higuchi, S.; Bertaggia, E.; Hung, A.; Shanmugarajah, N.; Guilz, N. C.; Gamarra, J. R.; Haeusler, R. A.

10.1101/2020.02.11.944124 — cell biology — Posted on 2020-02-12

2408 Investigating the conformational ensembles of intrinsically-disordered proteins with a simple physics-based model

Zhao, Y.; Cortes-Huerto, R.; Kremer, K.; Rudzinski, J. F.

10.1101/2020.02.11.943969 — biophysics — Posted on 2020-02-12

2409 A Safe Harbor-Targeted CRISPR/Cas9 Homology Independent Targeted Integration (HITI) System for Multi-Modality Reporter Gene-Based Cell Tracking

Kelly, J. J.; Saee-Marand, M.; Nyström, N. N.; Chen, Y.; Evans, M. M.; Hamilton, A. M.; Ronald, J. A.

10.1101/2020.02.10.942672 — bioengineering — Posted on 2020-02-12

2410 Characterization of Primed Adaptation in the Escherichia coli type I-E CRISPR-Cas System

Stringer, A. M.; Cooper, L. A.; Kadaba, S.; Shrestha, S.; Wade, J.

10.1101/2020.02.10.942821 — microbiology — Posted on 2020-02-12

2411 Modeling How Community Assembly Alters the Functioning of Ecosystems

Koffel, T.; Kremer, C. T.; Bannar-Martin, K.; Ernest, M. S. K.; Eisenhauer, N.; Roscher, C.; Sarmento Cabral, J.; Leibold, M. A.

10.1101/2020.02.10.942656 — ecology — Posted on 2020-02-12

2412 Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone

Wiegering, A.; Dildrop, R.; Vesque, C.; Schneider-Maunoury, S.; Gerhardt, C.

10.1101/2020.02.10.942300 — cell biology — Posted on 2020-02-12

2413 Vegetative nuclear positioning is required for calcium and ROS signaling in Arabidopsis pollen tubes

Moser, M.; Kirkpatrick, A.; Groves, N. R.; Meier, I.

10.1101/2020.02.10.942722 — plant biology — Posted on 2020-02-12

2414 The genome sequence of the Jean-Talon strain, an archeological tetraploid beer yeast from Quebec

Fijarczyk, A.; Henault, M.; Marsit, S.; Charron, G.; Fischborn, T.; Nicole-Labrie, L.; Landry, C.

10.1101/2020.02.11.944405 — genomics — Posted on 2020-02-12

2415 The evolution of sex is tempered by costly hybridization in Boechera (rock cress)

Rushworth, C. A.; Mitchell-Olds, T.

10.1101/2020.02.11.944256 — evolutionary biology — Posted on 2020-02-12

2416 Spatial Distribution of Discarded Vehicle Tires and Their Influence on Aedes albopictusand Culex quinquefasciatus Populations in New Orleans, Louisiana

Sallam, M. F.; Ahmed, T.; Lear, C.; Riegel, C.; Moise, I.

10.1101/2020.02.10.942706 — ecology — Posted on 2020-02-12

2417 Domestication of the emblematic white cheese-making fungus Penicillium camemberti and its diversification into two varieties

Ropars, J.; Didiot, E.; Rodriguez de la Vega, R. C.; Bennetot, B.; Coton, M.; Poirier, E.; Coton, E.; Snirc, A.; Le Prieur, S.; Giraud, T.

10.1101/2020.02.12.945238 — evolutionary biology — Posted on 2020-02-12

2418 Ubiquitin ligase component LRS1 and transcription factor CrHy5 act as a light switch for photoprotection in Chlamydomonas

Kruse, O.; Lämmermann, N.; Wulf, D.; Chang, K. S.; Wichmann, J.; Jang, J.; Jin, E.; Bräutigam, A.; Wobbe, L.

10.1101/2020.02.10.942334 — plant biology — Posted on 2020-02-12

2419 Epigenetic immune-modulation by Histone Deacetylase Activity (HDAC) of tissue and organ regeneration in Xenopsu laevis

Pentagna, N.; Soares dos Santos, F.; Martins de Almeida, F.; Garcia Abreu, J.; Levin, M.; Carneiro, K.

10.1101/2020.02.05.936294 — developmental biology — Posted on 2020-02-12

2420 Stress fibers are embedded in a contractile cortical network.

Vignaud, T.; Copos, C.; Leterrier, C.; Tseng, Q.; Blanchoin, L.; Mogilner, A.; THERY, M.; Kurzawa, L.

10.1101/2020.02.11.944579 — cell biology — Posted on 2020-02-12

2421 Optimal microbial pathway variants can be determined by large-scale bioenergetic evaluation in syntrophic propionate oxidation

Paton, M.; Hernandez, H. H.; Rodriguez, J.

10.1101/2020.02.07.939629 — bioengineering — Posted on 2020-02-12

2422 Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling

Amar, M.; Pramod, A. B.; Herrera, V. M.; Yu, N.-K.; Qiu, L. R.; Zhang, P.; Moran-Losada, P.; Trujillo, C. A.; Ellegood, J.; Urresti, J.; Chau, K.; Diedrich, J.; Chen, J.; Gutierrez, J.; Sebat, J.; Ramanathan, D.; Lerch, J. P.; Yates, J. R.; Muotri, A. R.; Iakoucheva, L. M.

10.1101/2020.02.07.939256 — neuroscience — Posted on 2020-02-12

2423 Metagenomic analysis of the cow, sheep, reindeer and red deer rumen

Glendinning, L.; Genc, B.; Wallace, R. J.; Watson, M.

10.1101/2020.02.12.945139 — microbiology — Posted on 2020-02-12

2424 Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

Aydin, O. Z.; Taflan, S. O.; Gurkaslar, C.; Firat-Karalar, E. N.

10.1101/2020.02.10.941658 — cell biology — Posted on 2020-02-12

2425 Linguistic structure and meaning organize neural oscillations into a content-specific hierarchy

Kaufeld, G.; Bosker, H. R.; Alday, P. M.; Meyer, A. S.; Martin, A. E.

10.1101/2020.02.05.935676 — neuroscience — Posted on 2020-02-12

2426 Age dependent changes in synaptic NMDA receptor composition in adult human cortical neurons

Pegasiou, C. M.; Zolnourian, A.; Gomez-Nicola, D.; Deinhardt, K.; Nicoll, J.; Ahmed, A.; Vajramani, G.; Grundy, P.; Verhoog, M.; Mansvelder, H.; Perry, V. H.; Bulters, D.; Vargas-Caballero, M.

10.1101/2020.01.21.913475 — neuroscience — Posted on 2020-02-12

2427 Normative Circuit Dynamics Across Human Cortex During Evidence Accumulation in Changing Environments

Murphy, P. R.; Wilming, N.; Hernandez-Bocanegra, D. C.; Prat Ortega, G.; Donner, T. H.

10.1101/2020.01.29.924795 — neuroscience — Posted on 2020-02-12

2428 Transcriptome-wide analysis of expressed resistance gene analogs (RGAs) in mango

Lantican, D. V.; Cortaga, C. Q.; Manohar, A. N. C.; dela Cueva, F. M.; Sison, M. L. J.

10.1101/2020.02.08.939736 — molecular biology — Posted on 2020-02-12

2429 The transmembrane serine protease inhibitors are potential antiviral drugs for 2019-nCoV targeting the insertion sequence-induced viral infectivity enhancement

Meng, T.; Cao, H.; Zhang, H.; Kang, Z.; Xu, D.; Gong, H.; Wang, J.; Li, Z.; Cui, X.; Xu, H.; Wei, H.; Pan, X.; Zhu, R.; Xiao, J.; Zhou, W.; Cheng, L.; Liu, J.

10.1101/2020.02.08.926006 — microbiology — Posted on 2020-02-12

2430 Cohesin-dependent and independent mechanisms support chromosomal contacts between promoters and enhancers

Thiecke, M. J.; Wutz, G.; Muhar, M.; Tang, W.; Bevan, S.; Malysheva, V.; Stocsits, R. R.; Neumann, T.; Zuber, J.; Fraser, P.; Schoenfelder, S.; Peters, J.-M.; Spivakov, M.

10.1101/2020.02.10.941989 — genomics — Posted on 2020-02-12

2431 Convolutional neural network MRI segmentation for fast and robust optimization of transcranial electrical current stimulation of the human brain

Sendra-Balcells, C.; Salvador, R.; Pedro, J. B.; Biagi, M. C.; Aubinet, C.; Manor, B.; Thibaut, A.; Laureys, S.; Lekadir, K.; Ruffini, G.

10.1101/2020.01.29.924985 — bioinformatics — Posted on 2020-02-12

2432 When to be Temperate: On the Fitness Benefits of Lysis vs. Lysogeny

Li, G.; Cortez, M. H.; Dushoff, J.; Weitz, J. S.

10.1101/709758 — ecology — Posted on 2020-02-12

2433 Transcytosis via the late endocytic pathway as a cell morphogenetic mechanism

Mathew, R.; Rios-Barrera, L. D.; Machado, P.; Schwab, Y.; Leptin, M.

10.1101/2020.01.16.909200 — cell biology — Posted on 2020-02-12

2434 PhISCS-BnB: A Fast Branch and Bound Algorithm for the Perfect Tumor Phylogeny Reconstruction Problem

Sadeqi Azer, E.; Rashidi Mehrabadi, F.; Li, X. C.; Malikic, S.; Schaffer, A. A.; Gertz, E. M.; Day, C.-P.; Perez-Guijarro, E.; Marie, K.; Lee, M. P.; Merlino, G.; Ergun, F.; Sahinalp, S. C.

10.1101/2020.02.06.938043 — bioinformatics — Posted on 2020-02-12

2435 Adenosine signaling and its downstream target mod(mdg4) modify the pathogenic effects of polyglutamine in a Drosophila model of Huntington's disease

Lin, Y.-H.; Ouns Maaroufi, H.; Kucerova, L.; Rouhova, L.; Filips, T.; Zurovec, M.

10.1101/2019.12.22.886143 — genetics — Posted on 2020-02-12

2436 The network structure and eco-evolutionary dynamics of CRISPR-induced immune diversification

Pilosof, S.; Alcala-Corona, S. A.; Wang, T.; Kim, T.; Maslov, S.; Whitaker, R. J.; Pascual, M.

10.1101/850800 — evolutionary biology — Posted on 2020-02-12

2437 Cargo licenses maturation of stalled endocytic sites through a regulatory checkpoint

Pedersen, R. T.; Hassinger, J. E.; Marchando, P.; Drubin, D. G.

10.1101/834523 — cell biology — Posted on 2020-02-12

2438 Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis

Fu, Y.; Jung, A. W.; Torne, R. V.; Gonzalez, S.; Vohringer, H.; Shmatko, A.; Yates, L.; Jimenez-Linan, M.; Moore, L.; Gerstung, M.

10.1101/813543 — bioinformatics — Posted on 2020-02-12

2439 Identification of Slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour

Garcia-Gonzalez, J.; Brock, A. J.; Parker, M. O.; Riley, R.; Jolliffe, D.; Sudwarts, A.; Teh, M.-T.; Busch-Nentwich, E. M.; Stemple, D. L.; Martineau, A. R.; Kaprio, J.; Palviainen, T.; Kuan, V.; Walton, R. T.; Brennan, C. H.

10.1101/453928 — genetics — Posted on 2020-02-12

2440 Competition and immune selection of multi-strain Plasmodium falciparum malaria

Gurarie, D.

10.1101/539676 — evolutionary biology — Posted on 2020-02-12

2441 A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

Lopez de Maturana, E.; Rodriguez, J.; Alonso, L.; Lao, O.; Molina-Montes, E.; Martin-Antoniano, I.; Gomez-Rubio, P.; Lawlor, R.; Carrato, A.; Hidalgo, M.; Iglesias, M.; Molero, X.; Lohr, M.; Michalski, C.; Perea, J.; O'Rorke, M.; Barbera, V.; Tardon, A.; Farre, A.; Munoz-Bellvis, L.; Crnogorac-Jurcevic, T.; Dominguez-Munoz, E.; Gress, T.; Greenhaf, W.; Sharp, L.; Arnes, L.; Cecchini, L.; Balsells, J.; Costello, E.; Ilzarbe, L.; Kleeff, J.; Kong, B.; Marquez, M.; Mora, J.; O'Driscoll, D.; Scarpa, A.; Ye, W.; Yu, J.; Investigators, P.; Garcia-Closas, M.; Kogevinas, M.; Rothman, N.; Silverman, D.

10.1101/2020.02.11.941351 — genetics — Posted on 2020-02-12

2442 mAML: an automated machine learning pipeline with a microbiome repository for human disease classification

Yang, F.; Zou, Q.

10.1101/2020.02.11.943316 — bioinformatics — Posted on 2020-02-12

2443 read_haps: using read haplotypes to detect same species contamination in DNA sequences.

Halldorsson, B. V.

10.1101/2020.02.11.941773 — bioinformatics — Posted on 2020-02-12

2444 iGenomics: Comprehensive DNA Sequence Analysis on your Smartphone

Palatnick, A.; Zhou, B.; Ghedin, E.; Schatz, M. C.

10.1101/2020.02.11.944132 — bioinformatics — Posted on 2020-02-12

2445 DeepNano-blitz: A Fast Base Caller for MinION Nanopore Sequencers

Boza, V.; Peresini, P.; Brejova, B.; Vinar, T.

10.1101/2020.02.11.944223 — bioinformatics — Posted on 2020-02-12

2446 Ecotype Simulation 2: An improved algorithm for efficiently demarcating microbial species from large sequence datasets

Wood, J. M.; Becraft, E. M.; Cohan, F.; Krizanc, D.; Ward, D. M.

10.1101/2020.02.10.940734 — bioinformatics — Posted on 2020-02-12

2447 Correlation between the immuno-virological response and the nutritional profile of treatment-experienced HIV-infected patients in the East region of Cameroon

Abba, A.; Fokam, J.; Kamgaing, R. S.; Yimga, J. F.; Kae, A. C.; Nka, A. D.; Tchouaket, M. C. T.; Chenwi, A. C.; Semengue, E. N. J.; Ndjolo, A.; Sosso, S. M.

10.1101/2020.02.11.943621 — microbiology — Posted on 2020-02-11

2448 Homophilic and heterophilic cadherin bond rupture forces in homo- or hetero-cellular systems measured by AFM based SCFS

Viji Babu, P. K.; Mirastschijski, U.; Belge, G.; Radmacher, M.

10.1101/2020.02.11.943597 — biophysics — Posted on 2020-02-11

2449 Expression of dlx genes in the normal and regenerating brain of adult zebrafish.

Weinschutz Mendes, H.; TAKTEK, M.; DURET, T.; Ekker, M.

10.1101/2020.02.11.943605 — neuroscience — Posted on 2020-02-11

2450 Site wind right: Identifying low-impact wind development areas in the Central United States

Hise, C.; Obermeyer, B.; Ahlering, M.; Wilkinson, J.; Fargione, J.

10.1101/2020.02.11.943613 — ecology — Posted on 2020-02-11

2451 Reduced language lateralization in autism and the broader autism phenotype as assessed with robust individual-subjects analyses

Jouravlev, O.; Kell, A.; Mineroff, Z.; Haskins, A.; Ayyash, D.; Kanwisher, N.; Fedorenko, E.

10.1101/2020.02.10.942698 — neuroscience — Posted on 2020-02-11

2452 Application of High Resolution Melt analysis (HRM) for screening haplotype variation in non-model plants: a case study of Honeybush (Cyclopia Vent.)

Galuszynski, N. C.; Potts, A. J.

10.1101/2020.02.05.921080 — molecular biology — Posted on 2020-02-11

2453 The transmembrane serine protease inhibitors are potential antiviral drugs for 2019-nCoV targeting the insertion sequence-induced viral infectivity enhancement

Meng, T.; Cao, H.; Zhang, H.; Kang, Z.; Xu, D.; Gong, H.; Wang, J.; Li, Z.; Cui, X.; Xu, H.; Wei, H.; Pan, X.; Zhu, R.; Xiao, J.; Zhou, W.; Cheng, L.; Liu, J.

10.1101/2020.02.08.926006 — microbiology — Posted on 2020-02-11

2454 The Essential Facts of Wuhan Novel Coronavirus Outbreak in China and Epitope-based Vaccine Designing against 2019-nCoV

Sarkar, B.; Ullah, M. A.; Johora, F. T.; Taniya, M. A.; Araf, Y.

10.1101/2020.02.05.935072 — immunology — Posted on 2020-02-11

2455 Cohesin-dependent and independent mechanisms support chromosomal contacts between promoters and enhancers

Thiecke, M. J.; Wutz, G.; Muhar, M.; Tang, W.; Bevan, S.; Malysheva, V.; Stocsits, R. R.; Neumann, T.; Zuber, J.; Fraser, P.; Schoenfelder, S.; Peters, J.-M.; Spivakov, M.

10.1101/2020.02.10.941989 — genomics — Posted on 2020-02-11

2456 Biogeochemical variability in the California Current System

Deutsch, C. A.; Frenzel, H.; McWilliams, J. C.; Renault, L.; Kessouri, F.; Howard, E. M.; Liang, J.-H.; Bianchi, D.; Yang, S.

10.1101/2020.02.10.942565 — ecology — Posted on 2020-02-11

2457 Predictive features of gene expression variation reveal a mechanistic link between expression variation and differential expression

Sigalova, O. M.; Shaeiri, A.; Forneris, M.; Furlong, E. E. M.; Zaugg, J. B.

10.1101/2020.02.10.942276 — genomics — Posted on 2020-02-11

2458 Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling

CELEN, C.; Chuang, J.-C.; Shen, S.; Otto, J. E.; Collings, C. K.; Luo, X.; Li, L.; Wang, Y.; Wang, Z.; Jia, Y.; Sun, X.; Nassour, I.; Park, J.; Ghaben, A.; Wang, T.; Wang, S. C.; Scherer, P. E.; Kadoch, C.; Zhu, H.

10.1101/2020.02.10.942615 — genetics — Posted on 2020-02-11

2459 Design of multi epitope-based peptide vaccine against E protein of human 2019-nCoV: An immunoinformatics approach

Abdelmageed, M. I.; Abdelmoneim, A. H.; Mustafa, M. I.; Elfadol, N. M.; Murshed, N. S.; Shantier, S. W.; Makhawi, A. M.

10.1101/2020.02.04.934232 — bioinformatics — Posted on 2020-02-11

2460 Molecular taxonomy of human ocular outflow tissues defined by single cell transcriptomics

Patel, G.; Fury, W.; Yang, H.; Gomez-Caraballo, M.; Bai, Y.; Yang, T.; Adler, C.; Wei, Y.; Ni, M.; Hu, Y.; Yancopoulos, G. D.; Stamer, W. D.; Romano, C.

10.1101/2020.02.10.942649 — cell biology — Posted on 2020-02-11

2461 Internal water storage buffering maintains plant function under drought as described by a general hydraulic model

Kaner, A.; Preisler, Y.; Grünzweig, J. M.; Mau, Y.

10.1101/2020.02.11.943563 — plant biology — Posted on 2020-02-11

2462 Frost and drought: effects of extreme weather events onstem carbon dynamics in a Mediterranean beech forest

D'Andrea, E.; Rezaie, N.; Prislan, P.; Gricar, J.; Muhr, J.; Collalti, A.; Matteucci, G.

10.1101/806026 — physiology — Posted on 2020-02-11

2463 In vivo interictal signatures of human periventricular heterotopia

Frazzini, V.; Whitmarsh, S.; Lambrecq, V.; Lehongre, K.; Yger, P.; Mathon, B.; Adam, C.; Hasboun, D.; Navarro, V.

10.1101/816173 — pathology — Posted on 2020-02-11

2464 A genome-wide screen for genes affecting spontaneous direct-repeat recombination in Saccharomyces cerevisiae

Novarina, D.; Desai, R.; Vaisica, J. A.; Ou, J.; Bellaoui, M.; Brown, G. W.; Chang, M.

10.1101/2020.02.11.943795 — genomics — Posted on 2020-02-11

2465 Profile-likelihood Bayesian model averaging for two-sample summary data Mendelian randomization in the presence of horizontal pleiotropy

Shapland, C. Y.; Zhao, Q.; Bowden, J.

10.1101/2020.02.11.943712 — genetics — Posted on 2020-02-11

2466 Niche theory for mutualism: A graphical approach to plant-pollinator network dynamics

Valdovinos, F. S.; Marsland, R.

10.1101/2020.02.11.943811 — ecology — Posted on 2020-02-11

2467 To improve the predictions of binding residues with DNA, RNA, carbohydrate, and peptide via multiple-task deep neural networks

Sun, Z.; Zheng, S.; Zhao, H.; Niu, Z.; Lu, Y.; Pan, Y.; Yang, Y.

10.1101/2020.02.11.943571 — bioinformatics — Posted on 2020-02-11

2468 Clustered γ-Protocadherins Regulate Cortical Interneuron Programmed Cell Death.

Mancia Leon, W. R.; Spatazza, J.; Rakela, B.; Chatterjee, A.; Pande, V.; Maniatis, T.; Hasenstaub, A. R.; Stryker, M. P.; Alvarez-Buylla, A.

10.1101/2020.01.14.906941 — neuroscience — Posted on 2020-02-11

2469 Evaluation of IL-1 blockade as an adjunct to linezolid therapy for tuberculosis in mice and macaques

Winchell, C. G. M.; Mishra, B. B.; Phuah, J. Y.; Saqib, M.; Nelson, S. J.; Maiello, P.; Causgrove, C. M.; Ameel, C. L.; Stein, B.; Borish, H. J.; White, A. G.; Klein, E. C.; Zimmerman, M. D.; Dartois, V.; Lin, P. L.; Sassetti, C. M.; Flynn, J. L.

10.1101/792390 — microbiology — Posted on 2020-02-11

2470 Wikidata as a FAIR knowledge graph for the life sciences

Waagmeester, A.; Stupp, G.; Burgstaller-Muehlbacher, S.; Good, B. M.; Griffith, M.; Griffith, O.; Hanspers, K.; Hermjakob, H.; Hudson, T. S.; Hybiske, K.; Keating, S. M.; Manske, M.; Mayers, M.; Mietchen, D.; Mitraka, E.; Pico, A. R.; Putman, T.; Riutta, A.; Queralt-Rosinach, N.; Schriml, L. M.; Shafee, T.; Slenter, D.; Stephan, R.; Thornton, K.; Tsueng, G.; Tu, R.; Ul-Hasan, S.; Willighagen, E.; Wu, C.; Su, A. I.

10.1101/799684 — bioinformatics — Posted on 2020-02-11

2471 Recognition of A Highly Conserved DSRCPTQ Epitope in Envelope Protein of Zika Virus Through in silico Approaches

Rahman, A.; Hossain, M. I.; Tamanna, S.; Ullah, M. N.

10.1101/2020.02.11.943530 — bioinformatics — Posted on 2020-02-11

2472 Intravital quantification of absolute cytoplasmic B cell calcium reveals dynamic signaling across B cell differentiation stages

Ulbricht, C.; Leben, R.; Rakhymzhan, A.; Kirchhoff, F.; Nitschke, L.; Radbruch, H.; Niesner, R. A.; Hauser, A. E.

10.1101/2019.12.13.872820 — immunology — Posted on 2020-02-11

2473 Informed dimension reduction of clinically-related genome-wide association summary data characterises cross-trait axes of genetic risk

Burren, O. S.; Reales, G.; Wong, L.; Bowes, J.; Lee, J. C.; Barton, A.; Lyons, P. A.; Smith, K. G.; Thomson, W.; Kirk, P. D.; Wallace, C.

10.1101/2020.01.14.905869 — genetics — Posted on 2020-02-11

2474 FANCY: Fast Estimation of Privacy Risk in Functional Genomics Data

Gursoy, G.; Brannon, C.; Navarro, F. C.; Gerstein, M.

10.1101/775338 — bioinformatics — Posted on 2020-02-11

2475 Improving spatial normalization of brain diffusion MRI to measure longitudinal changes of tissue microstructure in the cortex and white matter.

Jacobacci, F.; Jovicich, J.; Lerner, G.; Amaro, E.; Armony, J. L.; Doyon, J.; Della-Maggiore, V.

10.1101/590521 — neuroscience — Posted on 2020-02-11

2476 Prefrontal High Gamma in ECoG tags periodicity of musical rhythms in perception and imagination

Herff, S. A.; Herff, C.; Milne, A. J.; Johnson, G.; Shih, J. J.; Krusienski, D. J.

10.1101/784991 — neuroscience — Posted on 2020-02-11

2477 Control of septum thickness by a large protein ring

Wenzel, M.; Celik Gulsoy, I.; Gao, Y.; Willemse, J.; van Rosmalen, M. G. M.; wuite, G.; Roos, W.; Hamoen, L. W.

10.1101/771139 — microbiology — Posted on 2020-02-11

2478 The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration

Engstrom, A. K.; Walker, A. C.; Moudgal, R. A.; Myrick, D. A.; Kyle, S. M.; Katz, D. J.

10.1101/745133 — neuroscience — Posted on 2020-02-11

2479 Adaptive Bet-Hedging Revisited: Considerations of Risk and Time Horizon

Tal, O.; Tran, T. D.

10.1101/617084 — evolutionary biology — Posted on 2020-02-11

2480 Polynomial Phylogenetic Analysis of Tree Shapes

Liu, P.; Gould, M.; Colijn, C.

10.1101/2020.02.10.942367 — systems biology — Posted on 2020-02-11

2481 Protein-carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle

Hodson, N.; Dent, J. R.; Song, Z.; O'Leary, M.; Nicholson, T.; Jones, S. W.; Murray, J.; Jeromson, S.; Hamilton, D. L.; Breen, L.; Philp, A.

10.1101/2020.02.10.941054 — physiology — Posted on 2020-02-11

2482 Protein-protein interactions in neurodegenerative diseases: a conspiracy theory.

Thompson, T. B.; Kuhl, E.; Goriely, A.

10.1101/2020.02.10.942219 — neuroscience — Posted on 2020-02-11

2483 The fly liquid-food electroshock assay (FLEA) reveals opposite roles for neuropeptide F in avoidance of bitterness and shock.

Mishra, P.; Yang, S. E.; Montgomery, A. B.; Reed, A. R.; Rodan, A. R.; Rothenfluh, A.

10.1101/2020.02.10.942508 — neuroscience — Posted on 2020-02-11

2484 Dynamics of coherent activity between cortical areas defines a two-stage process of selective attention

Levichkina, E.; Kermani, M.; Saalmann, Y. B.; Vidyasagar, T. R.

10.1101/2020.02.09.940791 — neuroscience — Posted on 2020-02-11

2485 Anodal transcranial direct-current stimulation over the left dorsolateral prefrontal cortex and perception of emotional faces

Brasil-Neto, J. P.; Bernardes, T. S.; Rosa, C.; Iannone, A.; Garcia, A.; Tavares, M. C. H.

10.1101/2020.02.09.924910 — neuroscience — Posted on 2020-02-11

2486 Dynamic reconfiguration of functional brain networks during working memory training

Finc, K.; Bonna, K.; He, X.; Lydon, D. M.; Kühn, S.; Duch, W.; Bassett, D. S.

10.1101/685487 — neuroscience — Posted on 2020-02-11

2487 Allelic polymorphism shapes community function in evolving Pseudomonas aeruginosa populations

Azimi, S.; Roberts, A. E.; Peng, S.; Weitz, J. S.; McNally, A.; Brown, S. P.; Diggle, S. P.

10.1101/644724 — microbiology — Posted on 2020-02-11

2488 The Pathogenicity of 2019 Novel Coronavirus in hACE2 Transgenic Mice

10.1101/2020.02.07.939389 — microbiology — Posted on 2020-02-11

2489 Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin

Wang, Y.; Wang, G.; Li, Y.; Shen, H.; Chu, H.; Gao, N.; Xiao, J.

10.1101/2020.02.11.943233 — immunology — Posted on 2020-02-11

2490 The evolutionary forces shaping cis and trans regulation of gene expression within a population of outcrossing plants.

Josephs, E. B.; Lee, Y. W.; Wood, C. W.; Schoen, D.; Wright, S.; Stinchcombe, J.

10.1101/763870 — evolutionary biology — Posted on 2020-02-11

2491 Simplification of ribosomes in bacteria with tiny genomes

Nikolaeva, D. D.; Gelfand, M. S.; Garushyants, S. K.

10.1101/755876 — evolutionary biology — Posted on 2020-02-11

2492 Classification of Indian States and Union Territories based on their Soil Macronutrient and Organic Carbon Profiles

Kaushik, P.

10.1101/2020.02.10.930586 — ecology — Posted on 2020-02-11

2493 Mechanics regulate human embryonic stem cell self-organization to specify mesoderm

Muncie, J. M.; Ayad, N. M. E.; Lakins, J. N.; Weaver, V. M.

10.1101/2020.02.10.943076 — developmental biology — Posted on 2020-02-11

2494 Optimal timing for cancer screening and adaptive surveillance using mathematical modeling

Curtius, K.; Dewanji, A.; Hazelton, W. D.; Rubenstein, J. H.; Luebeck, E. G.

10.1101/2020.02.11.927475 — cancer biology — Posted on 2020-02-11

2495 Mobility of lower MA-helices for ion-conduction through lateral portals in 5-HT3A receptors

Stuebler, A. G.; Jansen, M.

10.1101/2020.02.10.943084 — biophysics — Posted on 2020-02-11

2496 Mutational signatures are jointly shaped by DNA damage and repair

Volkova, N. V.; Meier, B.; Gonzalez Huici, V.; Bertolini, S.; Gonzalez Rosado, S.; Abascal, F.; Martincorena, I.; Campbell, P. J.; Gartner, A.; Gerstung, M.

10.1101/686295 — genomics — Posted on 2020-02-11

2497 Amyloid-β induced membrane damage instigates tunneling nanotubes by exploiting PAK1 dependent actin remodulation

Damodaran, N.; Dilna, A.; Kielkopf, C. S.; Ollinger, K.; Kagedal, K.; Nath, S.

10.1101/655340 — cell biology — Posted on 2020-02-11

2498 Large-scale Quantification of Vertebrate Biodiversity in Ailaoshan Nature Reserve from Leech iDNA

Ji, Y.; Baker, C. C.; Li, Y.; Popescu, V. D.; Wang, Z.; Wang, J.; Wang, L.; Wu, C.; Hua, C.; Yang, Z.; Yang, C.; Xu, C. C.; Wen, Q.; Pierce, N. E.; Yu, D. W.

10.1101/2020.02.10.941336 — ecology — Posted on 2020-02-11

2499 High-Speed Super-Resolution Imaging Using Protein-Assisted DNA-PAINT

Filius, M.; Cui, T. J.; Ananth, A.; Docter, M.; Hegge, J.; van der Oost, J.; Joo, C.

10.1101/2020.02.11.943506 — biophysics — Posted on 2020-02-11

2500 Strain-aware assembly of genomes from mixed samples using flow variation graphs

Baaijens, J. A.; Stougie, L.; Schoenhuth, A.

10.1101/645721 — bioinformatics — Posted on 2020-02-11

2501 Impact of 3-dimensional genome organization, guided by cohesin and CTCF looping, on sex-biased chromatin interactions and gene expression in mouse liver

Matthews, B. J.; Waxman, D. J.

10.1101/577577 — genomics — Posted on 2020-02-11

2502 Exploring the coronavirus epidemic using the new WashU Virus Genome Browser

Flynn, J.; Purushotham, D.; Choudhary, M. N.; Zhuo, X.; Fan, C.; Matt, G.; Li, D.; Wang, T.

10.1101/2020.02.07.939124 — genomics — Posted on 2020-02-11

2503 Environmental variation mediates the evolution of anticipatory parental effects

Lind, M. I.; Zwoinska, M. K.; Andersson, J.; Carlsson, H.; Krieg, T.; Larva, T.; Maklakov, A. A.

10.1101/606103 — evolutionary biology — Posted on 2020-02-11

2504 CRISPR-Cas12a-assisted PCR tagging of mammalian genes

Fueller, J.; Herbst, K.; Meurer, M.; Gubicza, K.; Kurtulmus, B.; Knopf, J. D.; Kirrmaier, D.; Buchmuller, B.; Pereira, G.; Lemberg, M. K.; Knop, M.

10.1101/473876 — cell biology — Posted on 2020-02-11

2505 Plasticity in gene expression facilitates invasion of the desert environment in house mice

Bittner, N. K. J.; Mack, K. L.; Nachman, M. W.

10.1101/2020.02.10.939231 — evolutionary biology — Posted on 2020-02-11

2506 {Phi}X174 Attenuation by Whole Genome Codon Deoptimization

Van Leuven, J. T.; Ederer, M. M.; Burleigh, K.; Scott, L.; Hughes, R. A.; Codrea, V.; Ellington, A. D.; Wichman, H. A.; Miller, C. R.

10.1101/2020.02.10.942847 — genomics — Posted on 2020-02-11

2507 Recent bloom of filamentous algae in Lake Baikal is caused by Spirogyra Link., 1820 of local origin

Mincheva, E. V.; Peretolchina, T. E.; Triboy, T. I.; Bukin, Y. S.; Kravtsova, L. S.; Fedotov, A. P.; Sherbakov, D. Y.

10.1101/2020.02.10.942979 — evolutionary biology — Posted on 2020-02-11

2508 Cell cycle-associated expression patterns predict gene function in mycobacteria

Bandekar, A. C.; Subedi, S.; Ioerger, T. R.; Sassetti, C. M.

10.1101/2020.02.10.942268 — microbiology — Posted on 2020-02-11

2509 Metastable GPCR dimers trigger the basal signal by recruiting G-proteins

Kasai, R. S.; Fujiwara, T. K.; Kusumi, A.

10.1101/2020.02.10.929588 — biochemistry — Posted on 2020-02-11

2510 An essential membrane protein modulates the proteolysis of LpxC to control lipopolysaccharide synthesis in Escherichia coli

Fivenson, E. M.; Bernhardt, T. G.

10.1101/2020.02.10.942425 — microbiology — Posted on 2020-02-11

2511 FOXO Transcription Factors Activate Alternative Major Immediate Early Promoters to Induce Human Cytomegalovirus Reactivation

Hale, A. E.; Collins-McMillen, D.; Lenarcic, E. M.; Kamil, J. P.; Goodrum, F.; Moorman, N. J.

10.1101/2020.02.10.942433 — microbiology — Posted on 2020-02-11

2512 Varicella-Zoster Virus ORF9 Is an Antagonist of the DNA Sensor cGAS

Hertzog, J.; Rigby, R. E.; Roll, S.; Cursi, C.; Chauveau, L.; Davenne, T.; Rehwinkel, J.

10.1101/2020.02.11.943415 — immunology — Posted on 2020-02-11

2513 CAR T cells for solid tumors: genome-wide dysfunction signature confirms value of c-Jun overexpression, but signals heterogeneity

Benhenda, M.

10.1101/2020.02.07.939033 — immunology — Posted on 2020-02-11

2514 Simultaneous Profiling of DNA Copy Number Variations and Transcriptional Programs in Single Cells using RNA-seq

Madipour-Shirayeh, A.; Erdmann, N.; Leung-Hagesteijn, C.; Neri, P.; Tagoug, I.; Tiedemann, R. E.

10.1101/2020.02.10.942607 — genomics — Posted on 2020-02-11

2515 Remote-controlled insect navigation using plasmonic nanotattoos

Tadepalli, S.; Cao, S.; Saha, D.; Liu, K.-K.; Chen, A.; Bae, S. H.; Raman, B.; Singamaneni, S.

10.1101/2020.02.10.942540 — bioengineering — Posted on 2020-02-11

2516 Ecological success of sexual and asexual reproductive strategies invading an environmentally unstable habitat

Silva, W. T. A. F.; Nyqvist, A.; Jonsson, P. R.; Harding, K. C.

10.1101/2020.02.10.942466 — ecology — Posted on 2020-02-11

2517 Explosive sensing with insect-based biorobots

Saha, D.; Mehta, D.; Altan, E.; Chandak, R.; Traner, M.; Lo, R.; Gupta, P.; Singamaneni, S.; Chakrabartty, S.; Raman, B.

10.1101/2020.02.10.940866 — bioengineering — Posted on 2020-02-11

2518 Form and function: diverse homeostatic and immunomodulatory roles of immune cells in the developing lung revealed at single cell resolution

Domingo-Gonzalez, R.; Zanini, F.; Che, X.; Liu, M.; Jones, R. C.; Swift, M. A.; Quake, S. R.; Cornfield, D. N.; Alvira, C. M.

10.1101/2020.02.10.942359 — developmental biology — Posted on 2020-02-11

2519 Membrane-Bound O-Acyltransferase 7 (MBOAT7) is a Key Regulator of Glycolysis in Clear Cell Renal Carcinoma.

Neumann, C. K. A.; Massey, W.; Orabi, D.; Zhang, R.; Silver, D. J.; Lathia, J. D.; Brown, J. M.

10.1101/2020.02.10.942458 — cancer biology — Posted on 2020-02-11

2520 Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics

Hobson, C. M.; Kern, M.; O'Brien, T.; Stephens, A. D.; Falvo, M. R.; Superfine, R.

10.1101/2020.02.10.942581 — biophysics — Posted on 2020-02-11

2521 Cell phone digital microscopy using an oil droplet

Szydlowski, N. A.; Jing, H.; Alqashmi, M.; Hu, Y. S.

10.1101/2020.02.10.942490 — bioengineering — Posted on 2020-02-11

2522 Cysteamine-bicalutamide combination treatment restores alpha-ketoglutarate and corrects proximal tubule phenotype in cystinosis

Jamalpoor, A.; van Gelder, C. A.; Yousef Yengej, F. A.; Zaal, E. A.; Berlingerio, S. P.; Veys, K. R.; Pou Casellas, C.; Voskuil, K.; Essa, K.; Ammerlaan, C. M.; Rega, L. R.; van der Welle, R. E. N.; Lilien, M. R.; Rookmaaker, M. B.; Clevers, H.; Klumperman, J.; Levtchenko, E.; Berkers, C. R.; Verhaar, M. C.; Altelaar, M.; Masereeuw, R.; Janssen, M. J.

10.1101/2020.02.10.941799 — pharmacology and toxicology — Posted on 2020-02-11

2523 Astroglial FMRP modulates synaptic signaling and behavior phenotypes in FXS mouse model

Jin, S.-X.; Higashimori, H.; Schin, C.; Tamashiro, A. O.; Men, Y.; Chiang, R. M. S.; Jarvis, R.; Cox, D.; Feig, L.; Yang, Y.

10.1101/2020.02.10.941971 — neuroscience — Posted on 2020-02-11

2524 Normative modelling using deep autoencoders: a multi-cohort study on mild cognitive impairment and Alzheimer's disease

Pinaya, W. H. L.; Scarpazza, C.; Garcia-Dias, R.; Vieira, S.; Baecker, L.; da Costa, P. F.; Redolfi, A.; Frisoni, G. B.; Pievani, M.; Calhoun, V. D.; Sato, J. R.; Mechelli, A.; Alzheimer's Disease Neuroimaging Initiative, ; Australian Imaging Biomarkers and Lifestyle flagship study of ageing,

10.1101/2020.02.10.931824 — neuroscience — Posted on 2020-02-11

2525 Voltage-gated calcium channel subunit α2δ-3 shapes light responses of mouse retinal ganglion cells mainly in low and moderate light levels

Seitter, H.; Sothilingam, V.; Benkner, B.; Garcia Garrido, M.; Kling, A.; Pirone, A.; Seeliger, M.; Münch, T. A.

10.1101/2020.02.10.941807 — neuroscience — Posted on 2020-02-11

2526 A multimodal computational pipeline for 3D histology of the human brain

Mancini, M.; Casamitjana, A.; Peter, L.; Robinson, E.; Crampsie, S.; Thomas, D. L.; Holton, J. L.; Jaunmuktane, Z.; Iglesias, J. E.

10.1101/2020.02.10.941948 — neuroscience — Posted on 2020-02-11

2527 Convergent molecular, cellular, and neural signatures of major depressive disorder

Anderson, K. M.; Collins, M. A.; Kong, R.; Fang, K.; Li, J.; He, T.; Chekroud, A. M.; Yeo, B. T. T.; Holmes, A. J.

10.1101/2020.02.10.942227 — neuroscience — Posted on 2020-02-11

2528 Long-read Individual-molecule Sequencing Reveals CRISPR-induced Genetic Heterogeneity in Human ESCs

Bi, C.; Wang, L.; Yuan, B.; Zhou, X.; Li, Y.; Wang, S.; Pang, Y.; Gao, X.; Huang, Y.; Li, M.

10.1101/2020.02.10.942151 — molecular biology — Posted on 2020-02-11

2529 Autosomal Recessive Alzheimer disease (arAD): homozygosity mapping of genomic regions containing arAD loci

Moreno Grau, S.; Fernandez, M. V.; de Rojas, I.; Hernandez, I.; Farias, F.; Dudde, J. P.; Quintela, I.; Madrid, L.; Gonzalez-Perez, A.; Montrreal, L.; Garcia-Gonzalez, P.; Alarcon, E.; Alegret, M.; Maronas, O.; Pineda, J. A.; Macias, J.; GR@ACE & DEGESCO consortia, ; Alzheimer s Disease Neuroimaging Initiative, ; Marqui, M.; Valero, S.; Benaque, A.; Clarimon, J.; Bullido, M. J.; Garcia-Ribas, G.; Pastor, P.; Sanchez-Juan, P.; Alvarez, V.; Pinol-Ripoll, G.; Garcia-Alberca, J. M.; Royo, J. L.; Franco-Macias, E.; Mir, P.; Calero, M.; Rabano, A.; Avila, J.; Antunez, C.; Real, L. M.; Orellana, A.

10.1101/2020.02.10.941393 — genetics — Posted on 2020-02-11

2530 Shedding light on the control of CatSper Ca2+ channels by cAMP and chemicals used to probe cAMP signaling

Wang, T.; Young, S.; Tuettelmann, F.; Roepke, A.; Krallmann, C.; Kliesch, S.; Zeng, X.-H.; Brenker, C.; Struenker, T.

10.1101/2020.02.10.942029 — cell biology — Posted on 2020-02-11

2531 Repurposing of KLF5 activates a cell cycle signature during the progression from Barrett's oesophagus to oesophageal adenocarcinoma.

Rogerson, C.; Ogden, S.; Britton, E.; the OCCAMS consortium, ; Ang, Y.; Sharrocks, A. D.

10.1101/2020.02.10.941872 — cancer biology — Posted on 2020-02-11

2532 Functional Plasticity and Evolutionary Adaptation of Allosteric Regulation

Leander, M.; Yuan, Y.; Meger, A.; Cui, Q.; Raman, S.

10.1101/2020.02.10.942417 — biochemistry — Posted on 2020-02-11

2533 Intracellular Staphylococcus aureus employs the cysteine protease staphopain A to induce host cell death in epithelial cells

Stelzner, K.; Hertlein, T.; Sroka, A.; Moldovan, A.; Paprotka, K.; Kessie, D.; Mehling, H.; Potempa, J.; Ohlsen, K.; Fraunholz, M.; Rudel, T.

10.1101/2020.02.10.936575 — microbiology — Posted on 2020-02-11

2534 Activation of Rab11a and endocytosis by Phosphatidylinositol 4-kinase III beta promotes oncogenic signaling in breast cancer

MacDonald, S.; Harding, K.; Bilodeau, P.; de Souza, C.; Campa, C.; Hirsch, E.; Auer, R.; Lee, J.

10.1101/2020.02.10.942177 — cancer biology — Posted on 2020-02-11

2535 Amyloid aggregates accumulate in melanoma metastasis driving YAP mediated tumor progression

Matafora, V.; Farris, F.; Restuccia, U.; Tamburri, S.; Martano, G.; Bernardelli, C.; Pisati, F.; Casagrande, F.; Lazzari, L.; Marsoni, S.; Bonoldi, E.; Bachi, A.

10.1101/2020.02.10.941906 — cancer biology — Posted on 2020-02-11

2536 Severe acute respiratory syndrome-related coronavirus - The species and its viruses, a statement of the Coronavirus Study Group

Gorbalenya, A. E.

10.1101/2020.02.07.937862 — microbiology — Posted on 2020-02-11

2537 Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

Aydin, O. Z.; Taflan, S. O.; Gurkaslar, C.; Firat-Karalar, E. N.

10.1101/2020.02.10.941658 — cell biology — Posted on 2020-02-11

2538 Temperature-induced uncoupling of cell cycle regulators

Falahati, H.; Hur, W.; Di Tali, S.; Wieschaus, E. F.

10.1101/2020.02.11.943266 — cell biology — Posted on 2020-02-11

2539 Odd-skipped controls neurite morphology and affect cell survival in Drosophila Melanogaster CNS

larsen, c. W.; Bernard, c.

10.1101/2020.02.11.943373 — developmental biology — Posted on 2020-02-11

2540 Escargot is involved in labial and antennal imaginal disc development through two different developmental pathways.

Rosales, F.; Sanchez-Diaz, I.; Reynaud, E.; Narvaez, V.

10.1101/2020.02.10.942862 — developmental biology — Posted on 2020-02-11

2541 Imaging and tracking mRNA in live mammalian cells via fluorogenic photoaffinity labeling

Ayele, T.; Loya, T.; Valdez-Sinon, A.; Bassell, G.; Heemstra, J.

10.1101/2020.02.10.942482 — biochemistry — Posted on 2020-02-11

2542 Dissociable mechanisms govern when and how strongly reward attributes affect decisions

Maier, S. U.; Raja Beharelle, A.; Polania, R.; Ruff, C. C.; Hare, T. A.

10.1101/434860 — neuroscience — Posted on 2020-02-11

2543 Perceptual saccadic suppression starts in the retina

Idrees, S.; Baumann, M.-P.; Franke, F.; Muench, T. A.; Hafed, Z. M.

10.1101/562595 — neuroscience — Posted on 2020-02-11

2544 Metrics for Public Health Perspective Surveillance of Bacterial Antibiotic Resistance in Low- and Middle-Income Countries

Tosas Auguet, O.; Niehus, R.; Gweon, H. S.; Berkley, J. A.; Waichungo, J.; Njim, T.; Edgeworth, J. D.; Batra, R.; Chau, K.; Swann, J.; Walker, S. A.; Peto, T. E.; Crook, D. W.; Lamble, S.; Turner, P.; Cooper, B. S.; Stoesser, N.

10.1101/2020.02.10.941930 — genomics — Posted on 2020-02-11

2545 Mobile Element Insertions and Associated Structural Variants in Longitudinal Breast Cancer Samples

Steely, C. J.; Russell, K. L.; Feusier, J. E.; Qiao, Y.; Marth, G.; Jorde, L. B.

10.1101/2020.02.10.942680 — genomics — Posted on 2020-02-11

2546 Accurate, scalable cohort variant calls using DeepVariant and GLnexus

Yun, T.; Li, H.; Chang, P.-C.; Lin, M. F.; Carroll, A.; McLean, C. Y.

10.1101/2020.02.10.942086 — genomics — Posted on 2020-02-11

2547 The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis

Leitao, E.; Di Persio, S.; Laurentino, S.; Woeste, M.; Dugas, M.; Kliesch, S.; Neuhaus, N.; Horsthemke, B.

10.1101/2020.02.10.941724 — genetics — Posted on 2020-02-11

2548 Weighted minimizer sampling improves long read mapping

Jain, C.; Rhie, A.; Zhang, H.; Chu, C.; Koren, S.; Phillippy, A.

10.1101/2020.02.11.943241 — bioinformatics — Posted on 2020-02-11

2549 A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome

Gao, F.; Pan, X.; Dodd-Eaton, E. B.; Vera Recio, C. C.; Bojadzieva, J.; Mai, P. L.; Zelley, K.; Johnson, V. E.; Braun, D.; Nichols, K. E.; Garber, J. E.; Savage, S. A.; Strong, L. C.; Wang, W.

10.1101/2020.02.10.942409 — genetics — Posted on 2020-02-11

2550 Mapping short reads, faithfully

Valera Zorita, E.; Cortini, R.; Filion, G. J.

10.1101/2020.02.10.942599 — bioinformatics — Posted on 2020-02-11

2551 Recent ultra-rare inherited mutations identify novel autism candidate risk genes

Wilfert, A. B.; Turner, T. N.; Murali, S. C.; Hsieh, P.; Sulovari, A.; Wang, T.; Coe, B. P.; Guo, H.; Hoekzema, K.; Bakken, T. E.; Winterkorn, L. H.; Evani, U. S.; Byrska-Bishop, M.; Earl, R. K.; Bernier, R. A.; The SPARK Consortium, ; Zody, M. C.; Eichler, E. E.

10.1101/2020.02.10.932327 — genetics — Posted on 2020-02-11

2552 Real-time, functional intra-operative localization of rat cavernous nerve network using near-infrared cyanine voltage-sensitive dye imaging

Kang, J.; Le, H. N. D.; Karakus, S.; Malla, A. P.; Harraz, M. M.; Kang, J. U.; Burnett, A. L.; Boctor, E. M.

10.1101/537274 — biophysics — Posted on 2020-02-11

2553 A framework for implementing metaheuristic algorithms using intercellular communication

Gutierrez, M. E.; Ortiz, Y. M.; Carrion, J.

10.1101/2020.02.06.937979 — synthetic biology — Posted on 2020-02-11

2554 Effect of Interpopulation Spike-Timing-Dependent Plasticity on Synchronized Rhythms in Neuronal Networks with Inhibitory and Excitatory Populations

Kim, S.-Y.; Lim, W.

10.1101/576314 — neuroscience — Posted on 2020-02-11

2555 Retinotopic remapping of the visual system in deaf adults

Levine, A. T.; Yuen, K.; Gouws, A. D.; Wade, A. R.; Morland, A. B.; Codina, C.; Buckley, D.; Baseler, H. A.

10.1101/2020.01.31.923342 — neuroscience — Posted on 2020-02-11

2556 MinION-based DNA barcoding of preserved and non-invasively collected wildlife samples

Seah, A.; Lim, M. C. W.; McAloose, D.; Prost, S.; Seimon, T.

10.1101/2020.01.29.925081 — molecular biology — Posted on 2020-02-11

2557 Freshwater monitoring by nanopore sequencing

Urban, L.; Holzer, A.; Baronas, J. J.; Hall, M.; Braeuninger-Weimer, P.; Scherm, M. J.; Kunz, D. J.; Perera, S. N.; Martin-Herranz, D. E.; Tipper, E. T.; Salter, S. J.; Stammnitz, M. R.

10.1101/2020.02.06.936302 — microbiology — Posted on 2020-02-11

2558 Next generation sequencing to investigate genomic diversity in Caryophyllales

Pucker, B.; Feng, T.; Brockington, S.

10.1101/646133 — genomics — Posted on 2020-02-11

2559 Fitness costs of parasites explain multiple life history tradeoffs in a wild mammal

Albery, G. F.; Morris, A.; Morris, S.; Kenyon, F.; Nussey, D. H.; Pemberton, J. M.

10.1101/683094 — ecology — Posted on 2020-02-11

2560 Axonal mechanisms mediating GABA-A receptor inhibition of striatal dopamine release

Kramer, P. F.; Twedell, E. L.; Shin, J. H.; Zhang, R.; Khaliq, Z. M.

10.1101/2020.02.09.941179 — neuroscience — Posted on 2020-02-11

2561 CRNKL1 is a highly selective regulator of intron-retaining HIV-1 and cellular mRNAs

Xiao, H.; Wyler, E.; Milek, M.; Grewe, B.; Kirchner, P.; Ekici, A.; Silva, A. B. O. V.; Jungnickl, D.; Landthaler, M.; Ensser, A.; Überla, K.

10.1101/2020.02.04.934927 — microbiology — Posted on 2020-02-11

2562 Helices on interdomain interface couple catalysis in the ATPPase domain with allostery in Plasmodium falciparum GMP synthetase

Shivakumaraswamy, S.; Pandey, N.; Ballut, L.; Violot, S.; Aghajari, N.; Balaram, H.

10.1101/808618 — biochemistry — Posted on 2020-02-11

2563 Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

Kelmer Sacramento, E.; Kirkpatrick, J. M.; Mazzetto, M.; Baumgart, M.; Bartolome, A.; Di Sanzo, S.; Caterino, C.; Sanguanini, M.; Papaevgeniou, N.; Lefaki, M.; Childs, D.; Bagnoli, S.; Terzibasi Tozzini, E.; Di Fraia, D.; Romanov, N.; Sudmant, P.; Huber, W.; Chondrogianni, N.; Vendruscolo, M.; Cellerino, A.; Ori, A.

10.1101/577478 — systems biology — Posted on 2020-02-11

2564 In-situ detection of Tomato spotted wilt orthotospovirus from crude plant extracts using Reverse Transcriptase- Recombinase Polymerase Amplification (RT-RPA) in endpoint and real-time.

Iturralde Martinez, J. F.; Rosa, C.

10.1101/720623 — plant biology — Posted on 2020-02-11

2565 Tissue-specific transcriptome profiling of the Arabidopsis thaliana inflorescence stem reveals local cellular signatures.

Shi, D.; Jouannet, V.; Agusti, J.; Kaul, V.; Levitsky, V.; Sanchez, P.; Mironova, V. V.; Greb, T.

10.1101/2020.02.10.941492 — plant biology — Posted on 2020-02-11

2566 CHANging Consciousness Epistemically (CHANCE): An empirical method to convert the subjective content of consciousness into scientific data

Tanaka, D. H.; Tanabe, T.

10.1101/495523 — neuroscience — Posted on 2020-02-11

2567 EFFECT OF VISUAL CUEING ON TWO-LEGGED HOPPING VARIABILITY IN CHILDREN WITH AUTISM SPECTRUM DISORDER: A PILOT STUDY

Lidstone, D. E.; Dufek, J. S.

10.1101/2020.02.05.936476 — developmental biology — Posted on 2020-02-11

2568 Lipidomic and biophysical homeostasis of mammalian membranes counters dietary lipids perturbations to maintain cellular fitness

Levental, K. R.; Malmberg, E.; Symons, J. L.; Fan, Y.-Y.; Chapkin, R. S.; Ernst, R.; Levental, I.

10.1101/342873 — cell biology — Posted on 2020-02-11

2569 Electrophysiology prediction of single neurons based on their morphology

Michiels, M.

10.1101/2020.02.04.933697 — neuroscience — Posted on 2020-02-11

2570 Flexible contextual modulation of naturalistic texture perception in peripheral vision

Herrera, D.; Coen-Cagli, R.; Gomez-Sena, L.

10.1101/2020.01.24.918813 — neuroscience — Posted on 2020-02-11

2571 High-throughput single-cell functional elucidation of neurodevelopmental disease-associated genes reveals convergent mechanisms altering neuronal differentiation

Lalli, M. A.; Avey, D.; Dougherty, J. D.; Milbrandt, J.; Mitra, R. D.

10.1101/862680 — genomics — Posted on 2020-02-11

2572 Moonlighting α-PheRS connects JAK/STAT with Notch signaling for intestinal homeostasis

Ho, M. T.; Lu, J.; Suter, B.

10.1101/2019.12.19.882530 — cell biology — Posted on 2020-02-11

2573 Physical parameters characterizing dysfunction of neuronal cargo transport caused by the dynein inhibitor ciliobrevin

Hayashi, K.; Miyamoto, M. G.; Niwa, S.

10.1101/2020.02.07.934687 — biophysics — Posted on 2020-02-11

2574 MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection

Luu, P.-L.; Ong, P.-T.; Thai Huu Loc, T.; Lam, D.; Pidsley, R.; Stirzaker, C.; Clark, S.

10.1101/2020.02.09.941013 — bioinformatics — Posted on 2020-02-11

2575 A Heat Stress Responsive NAC Transcription Factor Heterodimer Plays Key Roles in Rice Caryopsis Filling

Ren, Y.; Huang, Z.; Jiang, H.; Wang, Z.; Wu, F.; Xiong, Y.; Yao, J.

10.1101/2020.02.08.939728 — plant biology — Posted on 2020-02-11

2576 Characterization of neural communication dynamics in the Ventral Attention Network across distinct spatial and spatio-temporal scales

Ghosh, P.; Roy, D.; Banerjee, A.

10.1101/2019.12.25.888446 — neuroscience — Posted on 2020-02-11

2577 Statistical analysis and optimality of biological systems

Mlynarski, W.; Hledik, M.; Sokolowski, T. R.; Tkacik, G.

10.1101/848374 — neuroscience — Posted on 2020-02-11

2578 Human Visual Search Follows Suboptimal Bayesian Strategy Revealed by a Spatiotemporal Computational Model

Zhou, Y.; Yu, Y.

10.1101/779652 — neuroscience — Posted on 2020-02-11

2579 P4HA2, a prognostic factor, promotes glioma proliferation, invasion, migration and EMT through collagen regulation and PI3K/AKT pathway

Lin, J.; Wu, X.; Wei, W.; Jin, M.; Cui, Y.; Jin, W.; Qiu, G.

10.1101/2020.02.05.935221 — cancer biology — Posted on 2020-02-11

2580 Dual Role of Cell-Cell Adhesion In Tumor Suppression and Proliferation Due to Collective Mechanosensing

Malmi-Kakkada, A. N.; Li, X.; Sinha, S.; Thirumalai, D.

10.1101/683250 — cancer biology — Posted on 2020-02-11

2581 Connecting actin polymer dynamics across multiple scales

Copos, C.; Bannish, B.; Gasior, K.; Pinals, R. L.; Rostami, M.; Dawes, A.

10.1101/2020.01.28.923698 — biophysics — Posted on 2020-02-11

2582 Geometry of Ranked Nearest Neighbour Interchange Space of Phylogenetic Trees

Collienne, L.; Elmes, K.; Fischer, M.; Bryant, D. J.; Gavryushkin, A.

10.1101/2019.12.19.883603 — bioinformatics — Posted on 2020-02-11

2583 Crowdsourced mapping of unexplored target space of kinase inhibitors

Cichonska, A.; Ravikumar, B.; Allaway, R. J.; Park, S.; Wan, F.; Isayev, O.; Li, S.; Mason, M. J.; Lamb, A.; Tanoli, Z.-u.-R.; Jeon, M.; Kim, S.; Popova, M.; Capuzzi, S.; Zeng, J.; Dang, K.; Koytiger, G.; Kang, J.; Wells, C. I.; Willson, T. M.; The IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, ; Oprea, T. I.; Schlessinger, A.; Drewry, D. H.; Stolovitzky, G. A.; Wennerberg, K.; Guinney, J.; Aittokallio, T.

10.1101/2019.12.31.891812 — biochemistry — Posted on 2020-02-11

2584 CRISPR-Cas12a exploits R-loop asymmetry to form double strand breaks

Cofsky, J. C.; Karandur, D.; Huang, C. J.; Witte, I. P.; Kuriyan, J.; Doudna, J. A.

10.1101/2020.02.10.937540 — biochemistry — Posted on 2020-02-11

2585 Gene transcription as a limiting factor in protein production and cell growth

Metzl-Raz, E.; Kafri, M.; Yaakov, G.; Barkai, N.

10.1101/626242 — systems biology — Posted on 2020-02-11

2586 Multitask learning for Transformers with application to large-scale single-cell transcriptomes

Pang, M.; Tegner, J.

10.1101/2020.02.05.935239 — genomics — Posted on 2020-02-11

2587 Regularized selection indices for breeding value prediction using hyper-spectral image data

Lopez-Cruz, M. A.; Olson, E.; Rovere, G.; Crossa, J.; Dreisigacker, S.; Mondal, S.; Singh, R.; de los Campos, G.

10.1101/625251 — genetics — Posted on 2020-02-11

2588 SnpHub: an easy-to-set-up web server framework for exploring large-scale genomic variation data in the post-genomic era with applications in wheat

Wang, W.; Wang, Z.; Li, X.; Ni, Z.; Hu, Z.; Xin, M.; Peng, H.; Yao, Y.; Sun, Q.; Guo, W.

10.1101/626705 — bioinformatics — Posted on 2020-02-11

2589 Task-evoked activity quenches neural correlations and variability across cortical areas

Ito, T.; Brincat, S. L.; Siegel, M.; Mill, R. D.; He, B. J.; Miller, E. K.; Rotstein, H. G.; Cole, M. W.

10.1101/560730 — neuroscience — Posted on 2020-02-11

2590 Variation in visual sensitivity predicts motion sickness in virtual reality

Fulvio, J. M.; Rokers, B.

10.1101/488817 — neuroscience — Posted on 2020-02-11

2591 Age associated microbiome modulation and its association with systemic inflammation in a Rhesus Macaque Model

Pallikuth, S.; Russell, K. B.; Sirupangi, T.; Mendez, R.; Kvistad, D. K.; Pahwa, R.; Villinger, F.; Banerjee, S.; Pahwa, S.

10.1101/813667 — microbiology — Posted on 2020-02-11

2592 Intra- and Inter-Specific Investigations of Skeletal DNA Methylation and Femur Morphology in Primates

Housman, G.; Quillen, E. E.; Stone, A. C.

10.1101/554618 — genomics — Posted on 2020-02-11

2593 The mammalian plasma membrane is defined by transmembrane asymmetries in lipid unsaturation, leaflet packing, and protein shape

Lorent, J. H.; Levental, K. R.; Ganesan, L.; Longsworth, G.; Sezgin, E.; Doktorova, M. N.; Lyman, E.; Levental, I.

10.1101/698837 — cell biology — Posted on 2020-02-11

2594 Protein allocation and enzymatic constraints explain Escherichia coli wildtype and mutant phenotypes

Alter, T. B.; Blank, L. M.; Ebert, B. E.

10.1101/2020.02.10.941294 — systems biology — Posted on 2020-02-10

2595 Classification and characterisation of livestock production systems in northern Tanzania

de Glanville, W. A.; Davis, A.; Allan, K. J.; Buza, J.; Claxton, J. R.; Crump, J. A.; Halliday, J. E. B.; Johnson, P. C. D.; Kibona, T. J.; Mmbaga, B. T.; Swai, E.; Uzzell, C.; Yoder, J.; Sharp, J.; Cleaveland, S.

10.1101/2020.02.10.941617 — systems biology — Posted on 2020-02-10

2596 Characterization of transgenic mouse lines for selectively targeting glial cells in dorsal root ganglia

Rabah, Y.; Rubino, B.; Moukarzel, E.; Agulhon, C.

10.1101/2020.02.10.941625 — neuroscience — Posted on 2020-02-10

2597 Differential expression and localization of thermosensitive Transient Receptor Potential Vanilloid (TRPV) channels in the mature sperm of white pekin duck (Anas platyrhynchos)

Majhi, R. K.; Kumar, A.; Giri, S. C.; Goswami, C.

10.1101/2020.02.10.941732 — cell biology — Posted on 2020-02-10

2598 EphrinB1 modulates glutamatergic inputs into POMC neurons and controls glucose homeostasis

Gervais, M.; Picard, A.; Thorens, B.; Croizier, S.

10.1101/2020.02.10.941765 — physiology — Posted on 2020-02-10

2599 Validity of Two-Dimensional Static Footprint in Medial Longitudinal Arch Evaluation and the Characteristics of Athletes' Footprints

Zhang, L.; Yu, D.; Lei, L.; Gao, Y.; Dong, J.; Yu, Z.; Yuan, Y.

10.1101/2020.02.10.941633 — genetics — Posted on 2020-02-10

2600 Abundance and Distribution of Heterelmis cf. glabra (Coleoptera: Elmidae) within Dolan Falls Preserve and the Devils River State Natural Area, Texas, USA

Diaz, P. H.; Gibson, J. R.; Norris, C.; Thompson, C.

10.1101/2020.02.10.941641 — ecology — Posted on 2020-02-10

2601 Automated flight interception traps for interval sampling of insects

Bolliger, J.; Collet, M.; Hohl, M.; Wermelinger, B.; Obrist, M. K.

10.1101/2020.02.10.941740 — ecology — Posted on 2020-02-10

2602 Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

Aydin, O. Z.; Taflan, S. O.; Firat-Karalar, E. N.; Gurkaslar, C.

10.1101/2020.02.10.941658 — cell biology — Posted on 2020-02-10

2603 Temperature, but not excess of glycogen, regulate post-mortem AMPK activity in muscle of steer carcasses.

Strobel, P.; Galaz, A.; Villaroel-Espindola, F.; Apaoblaza, A.; Slebe, J. C.; Jerez-Timaure, N.; Gallo, C.; Ramirez-Reveco, A.

10.1101/2020.02.10.941666 — biochemistry — Posted on 2020-02-10

2604 Modeling the spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration

Cura Costa, E.; Rodrigo Albors, A.; Tanaka, E. M.; Chara, O.

10.1101/2020.02.10.941443 — bioinformatics — Posted on 2020-02-10

2605 Universality of clonal dynamics poses fundamental limits to identify stem cell self-renewal strategies

Parigini, C.; Greulich, P.

10.1101/2020.02.10.941286 — systems biology — Posted on 2020-02-10

2606 Tissue-specific transcriptome profiling of the Arabidopsis thaliana inflorescence stem reveals local cellular signatures.

Shi, D.; Jouannet, V.; Agusti, J.; Kaul, V.; Levitsky, V.; Mironova, V. V.; Sanchez, P.; Greb, T.

10.1101/2020.02.10.941492 — plant biology — Posted on 2020-02-10

2607 Unfolded protein response and scaffold independent pheromone MAP kinase signalling control Verticillium dahliae growth, development and plant pathogenesis

Starke, J.; Harting, R.; Maurus, I.; Bremenkamp, R.; Kronstad, J. W.; Braus, G. H.

10.1101/2020.02.10.941450 — genetics — Posted on 2020-02-10

2608 Manipulation-based skills for anthropomorphic human-arm system based on integrated ANFIS and vector calculus

Le, T.; Le, A.

10.1101/2020.02.10.941344 — bioengineering — Posted on 2020-02-10

2609 Distance and Colour-based Scores for Blood Test Risk Stratification

Zenil, H.; Hernandez-Quiroz, F.; Hernandez-Orozco, S.; Saeb-Parsy, K.; Hernandez de la Cerda, H.; Riedel, J.

10.1101/2020.02.09.941096 — bioinformatics — Posted on 2020-02-10

2610 Mechanical scarification, seed origin, and substrate influence on germination of Samanea tubulosa

Regnier, L. d. L. P.

10.1101/2020.02.10.940759 — plant biology — Posted on 2020-02-10

2611 Putative TetR family transcriptional regulator Rv1019 of Mycobacterium tuberculosis is an auto-repressor and a negative regulator of mfd-mazG operon

Pushparajan, A. R.; Ramachandran, R.; Reji, J. G.; Ramakrishnan, A. K.

10.1101/2020.02.10.941963 — microbiology — Posted on 2020-02-10

2612 Ursolic acid improves the bacterial community mapping of the intestinal tract in liver fibrosis mice

Wan, S.; Huang, C.

10.1101/2020.02.10.941955 — microbiology — Posted on 2020-02-10

2613 The Amazon rainforest soundscape characterized through Information Theory quantifiers

Colonna, J. G.; Carvalho, J. R.; Rosso, O. A.

10.1101/2020.02.09.940916 — ecology — Posted on 2020-02-10

2614 Transcriptional control of apical protein clustering drives de novo cell polarity establishment in the early mouse embryo

Zhu, M.; Wang, P.; Handford, C.; Na, J.; Zernicka-Goetz, M.

10.1101/2020.02.10.942201 — developmental biology — Posted on 2020-02-10

2615 Gain-of-function mutation in Gli3 causes ventricular septal defects

Wiegering, A.; Adibi, P.; Ruether, U.; Gerhardt, C.

10.1101/2020.02.10.942144 — developmental biology — Posted on 2020-02-10

2616 Revisiting reptile home ranges: moving beyond traditional estimators with dynamic Brownian Bridge Movement Models

Silva, I.; Crane, M.; Marshall, B. M.; Strine, C. T.

10.1101/2020.02.10.941278 — ecology — Posted on 2020-02-10

2617 Acetylation of isoniazid - a novel mechanism of isoniazid resistance in Mycobacterium tuberculosis

K B, A.; Madhavan, A.; Abraham, B.; M, B.; K C, S.; P, N.; R, A. K.

10.1101/2020.02.10.941252 — biochemistry — Posted on 2020-02-10

2618 HDAC6 regulates radiosensitivity of non-small cell lung cancer by promoting degradation of Chk1

Zhang, X. M.; Moses, N.; Zhang, M.; Wu, J.-Y.; Hu, C.; Xiang, S.; Malysa, A.; Jang, H.; Chen, W.; Bai, W.; Bepler, G.

10.1101/2020.02.10.942573 — molecular biology — Posted on 2020-02-10

2619 Phosphorylation controls RNA binding and transcription by the influenza virus polymerase

Dawson, A. R.; Wilson, G. M.; Freiberger, E. C.; Mondal, A.; Coon, J. J.; Mehle, A.

10.1101/2020.02.10.942318 — microbiology — Posted on 2020-02-10

2620 An Image-Based Data-Driven Analysis of Cellular Architecture in a Developing Tissue

Hartmann, J.; Wong, M.; Gallo, E.; Gilmour, D.

10.1101/2020.02.10.941690 — developmental biology — Posted on 2020-02-10

2621 Fatty Acyl Availability Modulates Cardiolipin Composition and Alters Mitochondrial Function in HeLa Cells

Oemer, G.; Edenhofer, M.-L.; Lackner, K.; Leman, G.; Lindner, H. H.; Dubrac, S.; Zschocke, J.; Keller, M. A.

10.1101/2020.02.10.937433 — biochemistry — Posted on 2020-02-10

2622 Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms

Scacchetti, A.; Schauer, T.; Reim, A.; Apostolou, Z.; Campos Sparr, A.; Krause, S.; Heun, P.; Wierer, M.; Becker, P. B.

10.1101/2020.02.10.939793 — molecular biology — Posted on 2020-02-10

2623 High throughput screening identifies SOX2 as a Super Pioneer Factor that inhibits DNA methylation maintenance at its binding sites

Vanzan, L.; Soldati, H.; Ythier, V.; Anand, S.; Francis, N. J.; Murr, R.

10.1101/2020.02.10.941682 — genetics — Posted on 2020-02-10

2624 DYRK3-Controlled Phase Separation Organizes the Early Secretory Pathway

Gallo, R.; Rai, A. K.; Pelkmans, L.

10.1101/2020.02.10.941757 — cell biology — Posted on 2020-02-10

2625 SpliceViNCI: Visualizing the splicing of non-canonical introns through recurrent neural networks

Dutta, A.; Singh, K. K.; Anand, A.

10.1101/2020.02.09.940551 — bioinformatics — Posted on 2020-02-10

2626 Genomic evidence reveals SPA-regulated developmental and metabolic pathways in dark-grown Arabidopsis seedlings

Pham, V. N.; Paik, I.; Hoecker, U.; Huq, E.

10.1101/2020.02.10.941708 — plant biology — Posted on 2020-02-10

2627 Achilles tendon stiffness minimizes the energy cost in simulations of walking in older but not in young adults

Delabastita, T.; De Groote, F.; Vanwanseele, B.

10.1101/2020.02.10.941591 — physiology — Posted on 2020-02-10

2628 A Guide for Population-based Analysis of the Adolescent Brain Cognitive Development (ABCD) Study Baseline Data

Heeringa, S. G.; Berglund, P. A.

10.1101/2020.02.10.942011 — neuroscience — Posted on 2020-02-10

2629 The inducible lac operator-repressor system is functional in zebrafish cells

Nishizaki, S. S.; McDonald, T. L.; Farnum, G. A.; Holmes, M. J.; Drexel, M. L.; Switzenberg, J. A.; Boyle, A. P.

10.1101/2020.02.10.939223 — molecular biology — Posted on 2020-02-10

2630 Assessing the in vitro resistance development in Enterovirus 71 in the context of combination antiviral treatment

Lanko, K.; Shi, C.; Patil, S.; Delang, L.; Matthijnssens, J.; Mirabelli, C.; Neyts, J.

10.1101/2020.02.10.935536 — microbiology — Posted on 2020-02-10

2631 Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model

Ward, T. R.; Zhang, X.; Leung, L. C.; Zhou, B.; Muench, K.; Roth, J. G.; Khechaduri, A.; Plastini, M. J.; Charlton, C.; Pattni, R.; Ho, S.; Ho, M.; Huang, Y.; Hallmayer, J. F.; Mourrain, P.; Palmer, T. D.; Urban, A. E.

10.1101/2020.02.09.940965 — genetics — Posted on 2020-02-10

2632 Association of gut microbiota with metabolism in juvenile Atlantic Salmon

Dvergedal, H.; Sandve, S. R.; Klemetsdal, G.; Rudi, K.; Angell, I. L.

10.1101/2020.02.10.941245 — genetics — Posted on 2020-02-10

2633 Genetic predictors of participation in optional components of UK Biobank

Tyrrell, J.; Zheng, J.; Beaumont, R. N.; Hinton, K.; Richardson, T.; Wood, A. R.; Davey-Smith, G.; Frayling, T.; Tilling, K.

10.1101/2020.02.10.941328 — genetics — Posted on 2020-02-10

2634 The eukaryotic ribosomal protein S15/uS19 is involved in fungal development and its C-terminal tail contributes to stop codon recognition

Nguyen, T.-T.; Stahl, G.; Dequard-Chablat, M.; Contamine, V.; Hermann-Le Denmat, S.

10.1101/2020.02.09.940346 — genetics — Posted on 2020-02-10

2635 Determining which mechanisms underlie facilitation by tussocks in tropical high mountains and their relative importance

Pedraza, F.; Garcia-Meza, D.; Tovar, H.; Martorell, C.

10.1101/2020.02.10.942193 — ecology — Posted on 2020-02-10

2636 Regulation of T cell receptor signaling by protein acyltransferase DHHC21

Fan, Y.; Shayahati, B.; Tewari, R.; Boehning, D.; Akimzhanov, A. M.

10.1101/2020.02.10.942078 — cell biology — Posted on 2020-02-10

2637 Transcriptomic and Proteomic analysis of clear cell foci (CCF) in the human non-cirrhotic liver identifies several differentially expressed genes and proteins with functions in cancer cell biology and glycogen metabolism.

Metzendorf, C.; Wineberger, K.; Rausch, J.; Cigliano, A.; Calvisi, D. F.; Peters, K.; Sun, B.; Mennerich, D.; Kietzmann, T.; Dombrowski, F.; Ribback, S.

10.1101/2020.02.10.941211 — cancer biology — Posted on 2020-02-10

2638 The Alexnet-ResNet-Inception Network for Classifying Fruit Images

wenzhong, l.

10.1101/2020.02.09.941039 — bioinformatics — Posted on 2020-02-10

2639 Bursty expression enhances reliability of messaging in gene networks

dos Reis Gama, L.; Giovanini, G.; Balazsi, G.; Ferreira Ramos, A.

10.1101/2020.02.09.940684 — systems biology — Posted on 2020-02-10

2640 Combinatorial effect of miR-486-5p & miR-22-3p mimics thrombopoietin's impact on hematopoietic stem & progenitor cells

Kao, C.-Y.; Jiang, J.; PAPOUTSAKIS, E. T.

10.1101/2020.02.09.941104 — cell biology — Posted on 2020-02-10

2641 The Omics Discovery REST interface

Dass, G.; Vu, M.-T.; Xu, P.; Audain, E.; Hitz, M.-P.; Hermjakob, H.; Perez-Riverol, Y.

10.1101/2020.02.10.939967 — bioinformatics — Posted on 2020-02-10

2642 A Software Toolkit for TMS Electric-Field Modeling with Boundary Element Fast Multipole Method: An Efficient MATLAB Implementation

Makarov, S. N.; Wartman, W. A.; Daneshzand, M.; Fujimoto, K.; Raij, T.; Nummenmaa, A.

10.1101/2020.02.09.941021 — bioengineering — Posted on 2020-02-10

2643 A Note about the Individualized TMS Focality

Makarov, S. N.; Wartman, W. A.; Daneshzand, M.; Nummenmaa, A.

10.1101/2020.02.10.941062 — bioengineering — Posted on 2020-02-10

2644 Correlation network analysis based on untargeted LC-MS profiles of cocoa reveals processing stage and origin country

Kumar, S.; D'Souza, R. N.; Corno, M.; Ullrich, M. S.; Kuhnert, N.; Huett, M.-T.

10.1101/2020.02.09.940585 — systems biology — Posted on 2020-02-10

2645 Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation

Liu, S.; Harmston, N.; Glaser, T. L.; Wong, Y.; Zhong, Z.; Madan, B.; Virshup, D. M.; Petretto, E. G.

10.1101/2020.02.09.941005 — genomics — Posted on 2020-02-10

2646 Genome Wide Association Study of Resistance to PstS2 and Warrior Races of Stripe (Yellow) Rust in Bread Wheat Landraces.

Tehseen, M. M.; Tonk, F. A.; Tosun, M.; Amri, A.; Sansaloni, C. P.; Kurtulus, E.; Yazbek, M.; Al-Sham'aa, K.; Ozseven, I.; Safdar, L. B.; Shehadeh, A.; Nazari, K.

10.1101/2020.02.09.940775 — genetics — Posted on 2020-02-10

2647 The GINS complex is required for the survival of rapidly proliferating retinal and tectal progenitor cells during zebrafish development

Varga, M.; Csalyi, K.; Bertyak, I.; Menyhard, D. K.; Poole, R. J.; Cerveny, K. L.; Kovesdi, D.; Baratki, B.; Rouse, H.; Vad, Z.; Hawkins, T. L.; Stickney, H. L.; Cavodeassi, F.; Schwarz, Q.; Young, R. M.; Wilson, S. W.

10.1101/2020.02.09.940767 — genetics — Posted on 2020-02-10

2648 Pathogen community composition and co-infection patterns in a wild community of rodents

Abbate, J. L.; Galan, M.; Razzauti, M.; Sironen, T.; Voutilainen, L.; Henttonen, H.; Gasqui, P.; Cosson, J.-F.; Charbonnel, N.

10.1101/2020.02.09.940494 — ecology — Posted on 2020-02-10

2649 Weak predation strength promotes stable coexistence of predators and prey in the same chain and across chains

Wang, L.; Liu, Y. P.; Wang, R. W.

10.1101/2020.02.09.940874 — ecology — Posted on 2020-02-10

2650 Anthropogenic factors influence the occupancy of an invasive carnivore in a suburban preserve system

Vanek, J. P.; Rutter, A. U.; Preuss, T. S.; Jones, H. P.; Glowacki, G. A.

10.1101/2020.02.10.939959 — ecology — Posted on 2020-02-10

2651 Measuring aptamer folding energy using a molecular clamp

Qu, H.; Ma, Q.; Wang, L.; Mao, Y.; Eisenstein, M.; Soh, H. T.; Zheng, L.

10.1101/2020.02.10.941203 — biophysics — Posted on 2020-02-10

2652 ScaleQC: A Scalable Lossy to Lossless Solution for NGS Sequencing Data Compression

Yu, R.; Yang, W.

10.1101/2020.02.09.940932 — bioinformatics — Posted on 2020-02-10

2653 MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection

Luu, P.-L.; Ong, P.-T.; Thai Huu Loc, T.; Lam, D.; Pidsley, R.; Stirzaker, C.; Clark, S.

10.1101/2020.02.09.941013 — bioinformatics — Posted on 2020-02-10

2654 unCOVERApp: an interactive graphical application for clinical assessment of sequence coverage at the base-pair level

Iovino, E.; Seri, M.; Pippucci, T.

10.1101/2020.02.10.939769 — bioinformatics — Posted on 2020-02-10

2655 Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication

Zhang, L.; Lin, D.; Kusov, Y.; Nian, Y.; Ma, Q.; Wang, J.; von Brunn, A.; Leyssen, P.; Lanko, K.; Neyts, J.; de Wilde, A.; Snijder, E. J.; Liu, H.; Hilgenfeld, R.

10.1101/2020.02.10.936898 — biochemistry — Posted on 2020-02-10

2656 Parallel mechanisms of visual memory formation across distinct regions of the honey bee brain

Avalos, A.; Traniello, I. M.; Claudio, E. P.; Giray, T.

10.1101/2020.02.10.939355 — animal behavior and cognition — Posted on 2020-02-10

2657 Gut microbiome modulates behaviour and life history in two wild rodents

Jameson, J. W.; Reale, D.; Kembel, S. W.

10.1101/2020.02.09.940981 — ecology — Posted on 2020-02-10

2658 Alterations in Acylcarnitines, Amines, and Lipids Inform about Mechanism of Action of Citalopram/Escitalopram in Major Depression

Mahmoudiandehkordi, S.; Ahmed, A.; Bhattacharyya, S.; Han, X.; Baillie, R. A.; Arnold, M.; Skime, M. K.; St. John-Williams, L.; Moseley, M. A.; Thompson, J. W.; Louie, G.; Riva-Posse, P.; Craighead, W. E.; McDonald, W.; Krishnan, R.; Rush, A. J.; Frye, M. A.; Dunlop, B. W.; Weinshilboum, R. M.; The Mood Disorders Precision Medicine Consortium (MDPMC), ; Kaddurah-Daouk, R.

10.1101/2020.02.10.927012 — neuroscience — Posted on 2020-02-10

2659 Endogenous SIRT3 activity is dispensable for normal hearing recovery after noise exposure in young adult mice

Patel, S.; Shah, L.; Dang, N.; Tan, X.; Almudevar, A. L.; White, P. M.

10.1101/2020.02.05.935882 — neuroscience — Posted on 2020-02-10

2660 SAR1 paralogs differ biochemically in assembly of the COPII coat

Melville, D. B.; Studer, S.; Schekman, R.

10.1101/2020.02.09.940833 — cell biology — Posted on 2020-02-10

2661 Anti-cancer Drug Synergy Prediction in Understudied Tissues using Transfer Learning

Kim, Y.; Zheng, S.; Tang, J.; Zheng, W.; Li, Z.; Jiang, X.

10.1101/2020.02.05.932657 — bioinformatics — Posted on 2020-02-10

2662 Vezatin is required for the retrograde axonal transport of endosomes in Drosophila and zebrafish

Spinner, M. A.; Pinter, K.; Drerup, C. M.; Herman, T. G.

10.1101/2020.02.09.940890 — cell biology — Posted on 2020-02-10

2663 Both DNA binding domains of p53 are required for its ultra rapid recruitment to sites of UV damage

Wang, Y.-H.; Ho, T.; Hariharan, A.; Goh, H. C.; Sheetz, M.; Lane, D.

10.1101/2020.02.09.938993 — cell biology — Posted on 2020-02-10

2664 Differences in the free energies between the excited states of Aβ40 and Aβ42 monomers encode their distinct aggregation propensities

Chakraborty, D.; Straub, J. E.; Thirumalai, D.

10.1101/2020.02.09.940676 — biophysics — Posted on 2020-02-10

2665 Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells

Palacios, V.; Kimble, G. C.; Tootle, T. L.; Buszczak, M.

10.1101/2020.02.10.942326 — developmental biology — Posted on 2020-02-10

2666 Septins coordinate cell wall integrity and lipid metabolism in a sphingolipid-dependent process

Mela, A.; Momany, M.

10.1101/2020.02.09.940718 — cell biology — Posted on 2020-02-10

2667 A genome-wide screen in mice to identify cell-extrinsic regulators of pulmonary metastatic colonisation

van der Weyden, L.; Swiatkowska, A.; Iyer, V.; Speak, A. O.; Adams, D. J.

10.1101/2020.02.10.941401 — cancer biology — Posted on 2020-02-10

2668 CRISPR-Cas12a exploits R-loop asymmetry to form double strand breaks

Kuriyan, J.; Doudna, J. A.; Cofsky, J. C.; Karandur, D.; Huang, C.; Witte, I.

10.1101/2020.02.10.937540 — biochemistry — Posted on 2020-02-10

2669 Par3A and Par3B orchestrate podocyte architecture by regulating RhoA levels

Koehler, S.; Odenthal, J.; Jess, D. U.; Hoehne, M.; Juengst, C.; Graewe, F.; Helmstaedter, M.; Hagmann, H.; Walz, G.; Bloch, W.; Niessen, C.; Schermer, B.; Wodarz, A.; Denholm, B.; Benzing, T.; Iden, S.; Brinkkoetter, P. T.

10.1101/2020.02.10.933671 — cell biology — Posted on 2020-02-10

2670 BET Bromodomain Proteins Regulate Transcriptional Reprogramming in Genetic Dilated Cardiomyopathy

Antolic, A.; Wakimoto, H.; Jiao, Z.; Gorham, J. M.; DePalma, S. R.; Conner, D. A.; Lee, D. Y.; Qi, J.; Seidman, J. G.; Bradner, J. E.; Brown, J. D.; Haldar, S. M.; Seidman, C. E.; Burke, M. A.

10.1101/2020.02.09.940882 — cell biology — Posted on 2020-02-10

2671 Low bias DNA for sustainable and efficient data storage

Gao, Y.; Chen, X.; Hao, J.; Zhang, C.; Qiao, H.; Qi, H.

10.1101/2020.02.09.940411 — synthetic biology — Posted on 2020-02-10

2672 Structural variation in hippocampal dentations among healthy young adults

ten Hove, J.; Poppenk, J.

10.1101/2020.02.09.940726 — neuroscience — Posted on 2020-02-10

2673 Suppressing and amplifying neural oscillations in real-time using phase-locked electrical stimulation: concept, optimization and in-vivo testing

Escobar Sanabria, D.; Johnson, L. A.; Yu, Y.; Busby, Z.; Nebeck, S.; Zhang, J.; Harel, N.; Johnson, M. D.; Molnar, G. F.; Vitek, J. L.

10.1101/2020.02.09.940643 — neuroscience — Posted on 2020-02-10

2674 Shaping Brain Structure: Genetic and Phylogenetic Axes of Macro Scale Organization of Cortical Thickness

Valk, S. L.; Xu, T.; Margulies, D. S.; Kahrabian Masouleh, S.; Paquola, C.; Goulas, A.; Kochunov, P.; Smallwood, J.; Yeo, B. T. T.; Bernhardt, B. C.; Eickhoff, S. B.

10.1101/2020.02.10.939561 — neuroscience — Posted on 2020-02-10

2675 Nyctinastic thallus movement in the liverwort Marchantia polymorpha is regulated by a circadian clock

Lagercrantz, U.; Billhardt, A.; Rousku, S. N.; Eklund, D. M.

10.1101/2020.02.09.940403 — plant biology — Posted on 2020-02-10

2676 Axonal mechanisms mediating GABA-A receptor inhibition of striatal dopamine release

Kramer, P. F.; Twedell, E. L.; Shin, J. H.; Zhang, R.; Khaliq, Z. M.

10.1101/2020.02.09.941179 — neuroscience — Posted on 2020-02-10

2677 Delta oscillations are a robust biomarker of dopamine depletion severity and motor dysfunction in awake mice

Whalen, T. C.; Willard, A. M.; Rubin, J. E.; Gittis, A. H.

10.1101/2020.02.09.941161 — neuroscience — Posted on 2020-02-10

2678 INSULIN-LIKE GROWTH FACTOR I MODULATES VULNERABILITY TO STRESS THROUGH OREXIN NEURONS

Fernandez de Sevilla, M. E.; Pignatelli, J.; Mendez, P.; Zegarra-Valdivia, J. A.; Torres Aleman, I.

10.1101/2020.02.10.941377 — neuroscience — Posted on 2020-02-10

2679 Cortical network mechanisms of response inhibition

Schaum, M.; Pinzuti, E.; Sebastian, A.; Lieb, K.; Fries, P.; Mobascher, A.; Jung, P.; Wibral, M.; Tuescher, O.

10.1101/2020.02.09.940841 — neuroscience — Posted on 2020-02-10

2680 A whole-brain connectivity map of mouse insular cortex

Gehrlach, D. A.; Gaitanos, T. N.; Klein, A. S.; Weiand, C.; Hennrich, A. A.; Conzelmann, K.-K.; Gogolla, N.

10.1101/2020.02.10.941518 — neuroscience — Posted on 2020-02-10

2681 Cross-sectional and longitudinal associations of threat and deprivation on cognition, emotional processing and psychopathology in children and adolescents

Schafer, J. L.; McLaughlin, K. A.; Manfro, G. G.; Pan, P.; Rohde, L. A.; Miguel, E. C.; Salum, G. A.

10.1101/2020.02.09.940858 — neuroscience — Posted on 2020-02-10

2682 Stochastic synchronization of dynamics on the human connectome

Pang, J. C.; Gollo, L. L.; Roberts, J. A.

10.1101/2020.02.09.940817 — neuroscience — Posted on 2020-02-10

2683 mRNA secondary structure stability regulates bacterial translation insulation and re-initiation

Chemla, Y.; Peeri, M.; Heltberg, M. L.; Eichler, J.; Jensen, M. H.; Tuller, T.; Alfonta, L.

10.1101/2020.02.10.941153 — molecular biology — Posted on 2020-02-10

2684 Tracing Evolutionary Ages of Cancer-Driving Sites by Cancer Somatic Mutations

Gu, X.; Zhou, Z.; Yang, J.

10.1101/2020.02.09.940528 — evolutionary biology — Posted on 2020-02-10

2685 Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

Aydin, O. Z.; Taflan, S. O.; Firat-Karalar, E. N.; Gurkaslar, C.

10.1101/2020.02.10.941658 — cell biology — Posted on 2020-02-10

2686 Discovery of a cryptic allosteric site in Ebola's 'undruggable' VP35 protein using simulations and experiments

Cruz, M. A.; Frederick, T. E.; Singh, S.; Vithani, N.; Zimmerman, M. I.; Porter, J. R.; Moeder, K. E.; Amarasinghe, G. K.; Bowman, G. R.

10.1101/2020.02.09.940510 — biochemistry — Posted on 2020-02-10

2687 The architecture of protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit

Kraushar, M. L.; Krupp, F.; Turko, P.; Ambrozkiewicz, M. C.; Sprink, T.; Imami, K.; Vieira-Vieira, C. H.; Schaub, T.; Harnett, D.; Munster-Wandowski, A.; Burger, J.; Zinnall, U.; Borisova, E.; Yamamoto, H.; Rasin, M.-R.; Beule, D.; Landthaler, M.; Mielke, T.; Tarabykin, V.; Vida, I.; Selbach, M.; Spahn, C. M. T.

10.1101/2020.02.08.939488 — neuroscience — Posted on 2020-02-10

2688 Automated flight interception traps for interval sampling of insects

Bolliger, J.; Collet, M.; Hohl, M.; Wermelinger, B.; Obrist, M. K.

10.1101/2020.02.10.941740 — ecology — Posted on 2020-02-10

2689 Temperature, but not excess of glycogen, regulate post-mortem AMPK activity in muscle of steer carcasses.

Strobel, P.; Galaz, A.; Villaroel-Espindola, F.; Apaoblaza, A.; Slebe, J. C.; Jerez-Timaure, N.; Gallo, C.; Ramirez-Reveco, A.

10.1101/2020.02.10.941666 — biochemistry — Posted on 2020-02-10

2690 Genetic variants drive altered epigenetic regulation of endotoxin tolerance in BTBR macrophages

Ciernia, A. V.; Link, V.; Careaga, M.; LaSalle, J.; Ashwood, P.

10.1101/2020.02.08.940296 — molecular biology — Posted on 2020-02-10

2691 Geometric Potentials from Deep Learning Improve Prediction of CDR H3 Loop Structures

Ruffolo, J. A.; Guerra, C.; Mahajan, S. P.; Sulam, J.; Gray, J. J.

10.1101/2020.02.09.940254 — biophysics — Posted on 2020-02-10

2692 An urn model approach to stochastic modeling of regulated gene expression yields physically intuitive solutions for probability distributions

Choudhary, K.; Narang, A.

10.1101/2020.02.09.940452 — biophysics — Posted on 2020-02-10

2693 Recording the age of RNA with deamination

Rodriques, S. G.; Chen, L. M.; Liu, S.; Zhong, E. D.; Scherrer, J. R.; Boyden, E. S.; Chen, F.

10.1101/2020.02.08.939983 — synthetic biology — Posted on 2020-02-10

2694 Brown Adipose Tissue is Associated with Improved Cardiometabolic Health and Regulates Blood Pressure

Becher, T.; Palanisamy, S.; Kramer, D. J.; Marx, S. J.; Wibmer, A. G.; Del Gaudio, I.; Butler, S. D.; Jiang, C. S.; Vaughan, R.; Schoder, H.; Di Lorenzo, A.; Mark, A.; Cohen, P.

10.1101/2020.02.08.933754 — physiology — Posted on 2020-02-10

2695 Plasmin improves oedematous blood-gas barrier by cleaving epithelial sodium channels

Zhao, R.; Ali, G.; Nie, H.-G.; Chang, Y.; Bhattarai, D.; Su, X.; Zhao, X.; Matthay, M. A.; Ji, H.-L.

10.1101/2020.02.09.940619 — pharmacology and toxicology — Posted on 2020-02-10

2696 Modelling thalamocortical circuitry shows visually induced LTP changes laminar connectivity in human visual cortex

Sumner, R. L.; Spriggs, M. J.; Shaw, A. D.

10.1101/2020.02.08.940155 — neuroscience — Posted on 2020-02-10

2697 Wheat pathogen Zymoseptoria tritici N-myristoyltransferase inhibitors: on-target antifungal activity and an unusual metabolic defense mechanism

Fedoryshchak, R. O.; Ocasio, C. A.; Strutton, B.; Mattocks, J.; Corran, A. J.; Tate, E. W.

10.1101/2020.02.09.940536 — cell biology — Posted on 2020-02-10

2698 Rapid Prototyping of Wireframe Scaffolded DNA Origami using ATHENA

Jun, H.; Wang, X.; Bricker, W.; Jackson, S.; Bathe, M.

10.1101/2020.02.09.940320 — biophysics — Posted on 2020-02-10

2699 Supervised and Unsupervised Classification of Cocoa Bean Origin and Processing using Liquid Chromatography-Mass Spectrometry

Kumar, S.; D'Souza, R. N.; Behrends, B.; Corno, M.; Ullrich, M. S.; Kuhnert, N.; Huett, M.-T.

10.1101/2020.02.09.940577 — bioinformatics — Posted on 2020-02-10

2700 Lower intake of animal-based products links to improved weight status, independent of depressive symptoms and personality in the general population

Medawar, E.; Enzenbach, C.; Roehr, S.; Villringer, A.; Riedel-Heller, S.; Witte, A. V.

10.1101/2020.02.09.940460 — neuroscience — Posted on 2020-02-10

2701 ENVIRONMENTAL PERTURBATIONS AND TRANSITIONS BETWEEN ECOLOGICAL AND EVOLUTIONARY EQUILIBRIA: AN ECO-EVOLUTIONARY FEEDBACK FRAMEWORK

Coulson, T.

10.1101/509067 — ecology — Posted on 2020-02-10

2702 Administration of fusion cytokines induces tumor regression and systemic antitumor immunity

Zhang, J.; Zhao, X.

10.1101/2020.02.09.940379 — cancer biology — Posted on 2020-02-10

2703 The parotid secretory protein BPIFA2 is a salivary surfactant that affects LPS action

Nandula, S. R.; Huxford, I.; Wheeler, T. T.; Aparicio, C.; Gorr, S.-U.

10.1101/2020.02.08.940163 — physiology — Posted on 2020-02-10

2704 Aesthetic preference for art emerges from a weighted integration over hierarchically structured visual features in the brain

Iigaya, K.; Yi, S.; Wahle, I. A.; Tanwisuth, K.; O'Doherty, J. P.

10.1101/2020.02.09.940353 — neuroscience — Posted on 2020-02-10

2705 Diverse Arctic lake sediment microbiota shape methane emission temperature sensitivity

Emerson, J. B.; Varner, R. K.; Wik, M.; Parks, D. H.; Neumann, R. B.; Johnson, J. E.; Singleton, C. M.; Woodcroft, B. J.; Tollerson, R.; Owusu-Dommey, A.; Binder, M.; Freitas, N. L.; Crill, P. M.; Saleska, S. R.; Tyson, G. W.; Rich, V. I.

10.1101/2020.02.08.934661 — microbiology — Posted on 2020-02-10

2706 Binding affinity and conformational preferences influence kinetic stability of short oligonucleotides on carbon nanotubes

Alizadehmojarad, A.; Zhou, X.; Beyene, A. G.; Chacon, K.; Sung, Y.; Landry, M. P.; Vukovic, L.

10.1101/2020.02.08.939918 — biophysics — Posted on 2020-02-10

2707 A Heat Stress Responsive NAC Transcription Factor Heterodimer Plays Key Roles in Rice Caryopsis Filling

Ren, Y.; Huang, Z.; Jiang, H.; Wang, Z.; Wu, F.; Xiong, Y.; Yao, J.

10.1101/2020.02.08.939728 — plant biology — Posted on 2020-02-10

2708 Measuring spectrally-resolved information transfer for sender- and receiver-specific frequencies

Pinzuti, E.; Wollsdtadt, P.; Gutknecht, A.; Tuescher, O.; Wibral, M.

10.1101/2020.02.08.939744 — neuroscience — Posted on 2020-02-10

2709 The P600 ERP component as an index of rational error correction within a noisy-channel framework of human communication

Ryskin, R. A.; Stearns, L.; Eddy, M.; Bergen, L.; Fedorenko, E.; Gibson, E.

10.1101/2020.02.08.930214 — neuroscience — Posted on 2020-02-10

2710 Deep Neural Networks Point to Mid-level Complexity ofRodent Object Vision

Vinken, K.; Op de Beeck, H.

10.1101/2020.02.08.940189 — neuroscience — Posted on 2020-02-10

2711 Transcriptome-wide analysis of expressed resistance gene analogs (RGAs) in mango

Lantican, D. V.; Cortaga, C. Q.; Manohar, A. N. C.; dela Cueva, F. M.; Sison, M. L. J.

10.1101/2020.02.08.939736 — molecular biology — Posted on 2020-02-10

2712 Textile waste and microplastic induce activity and development of unique hydrocarbon-degrading marine bacterial communities

Girard, E.; Kaliwoda, M.; Schmahl, W. W.; Woerheide, G.; Orsi, W. D.

10.1101/2020.02.08.939876 — microbiology — Posted on 2020-02-10

2713 Defining endemism levels for biodiversity conservation: tree species in the Atlantic Forest hotspot

Lima, R. A. F.; Souza, V. C.; de Siqueira, M. F.; ter Steege, H.

10.1101/2020.02.08.939900 — ecology — Posted on 2020-02-10

2714 Beyond range size: drivers of species' geographic range structure in European plants

Csergo, A. M.; Broennimann, O.; Guisan, A.; Buckley, Y. M.

10.1101/2020.02.08.939819 — ecology — Posted on 2020-02-10

2715 Intracorneal delivery of HSV-targeting CRISPR/Cas9 mRNA prevents herpetic stromal keratitis

Yin, D.; Ling, S.; Wang, D.; Jiang, H.; Paludan, S. R.; Hong, J.; Cai, Y.

10.1101/2020.02.08.934125 — bioengineering — Posted on 2020-02-10

2716 Rescue Ebola Patients in silico

Zhao, G.; Binder, S.; Pongratz, G.; Meyer-Hermann, M.

10.1101/2020.02.08.939777 — systems biology — Posted on 2020-02-10

2717 Valorization of CO2 through lithoautotrophic production of sustainable chemicals in Cupriavidus necator

Nangle, S. N.; Ziesack, M.; Buckley, S.; Trivedi, D.; Loh, D.; Nocera, D. G.; Silver, P. A.

10.1101/2020.02.08.940007 — synthetic biology — Posted on 2020-02-10

2718 GSK3 activity is a cell fate switch that balances the ratio of vascular cell type

Tamaki, T.; Oya, S.; Naito, M.; Ozawa, Y.; Furuya, T.; Saito, M.; Sato, M.; Wakazaki, M.; Toyooka, K.; Fukuda, H.; Helariutta, Y.; Kondo, Y.

10.1101/2020.02.08.939595 — plant biology — Posted on 2020-02-10

2719 Mathematical Model of Colorectal Cancer Initiation

Paterson, C.; Clevers, H.; Bozic, I.

10.1101/2020.02.08.939603 — cancer biology — Posted on 2020-02-10

2720 Data-driven models reveal mutant cell behaviors important for myxobacterial aggregation

Zhang, Z.; Cotter, C.; Lyu, Z.; Shimkets, L.; Igoshin, O. A.

10.1101/2020.02.08.939462 — biophysics — Posted on 2020-02-10

2721 Trichinella spiralis secretes abundant unencapsulated small RNAs with potential effects on host gene expression

Taylor, P. J.; Faruqu, F.; Al-Jamal, K.; Quigley, B.; Beeby, M.; Selkirk, M.; Sarkies, P.

10.1101/2020.02.09.940601 — molecular biology — Posted on 2020-02-10

2722 ABCF1 regulates dsDNA-induced immune responses in human airway epithelial cells

Cao, Q. T.; Aguiar, J. A.; Tremblay, B. J.-M.; Abbas, N.; Tiessen, N.; Revill, S.; Makhdami, N.; Ayoub, A.; Cox, G.; Ask, K.; Doxey, A. C.; Hirota, J. A.

10.1101/2020.02.08.940023 — immunology — Posted on 2020-02-10

2723 Survival and Proliferation of T-cell Acute Lymphoblastic Leukaemia Depends on mTOR-regulated Glutamine Uptake and EAAT1 Activity

Stanulovic, V. S.; Reed, M. A. C.; Patani, H.; Potluri, S.; Georgiadou, E.; Roberts, J.; Sarkar, S.; Pratt, G. E.; Jones, A. M.; Gunther, U. L.; Ludwig, C.; Hoogenkamp, M.

10.1101/2020.02.08.939694 — cancer biology — Posted on 2020-02-10

2724 Antisense ncRNAs during early vertebrate development are divided in groups with distinct features

Pillay, S.; Takahashi, H.; Carninci, P.; Kanhere, A.

10.1101/2020.02.08.940148 — genomics — Posted on 2020-02-10

2725 Hyaluronan-NK cell Interaction Controls the Primary Vascular Barrier during Early Pregnancy

Hadas, R.; Gershon, E.; Cohen, A.; Stroganov, S.; Atrakchi, O.; Lazar, S.; Golani, O.; Dassa, B.; Elbaz, M.; Cohen, G.; Kartvelishvily, E.; Eilam, R.; Dekel, N.; Neeman, M.

10.1101/2020.02.09.940544 — developmental biology — Posted on 2020-02-10

2726 The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Duran-Ferrer, M.; Clot, G.; Nadeu, F.; Beekman, R.; Bauman, T.; Nordlund, J.; Marincevic-Zuniga, Y.; Lonnerholm, G.; Rivas, A.; Martin, S.; Ordonez, R.; Castellano, G.; Kulis, M.; Queiros, A.; Seung-Tae, L.; Wiemels, J.; Royo, R.; Puiggros, M.; Lu, J.; Gine, E.; Bea, S.; Jares, P.; Agirre, X.; Prosper, F.; Lopez-Otin, C.; Puente, X. S.; Oakes, C.; Zenz, T.; Delgado, J.; Lopez-Guillermo, A.; Campo, E.; Martin-Subero, J. I.

10.1101/2020.02.06.937383 — cancer biology — Posted on 2020-02-10

2727 Machine Learning Prediction of Incidence of Alzheimers Disease Using Large-Scale Administrative Health Data

Park, J. H.; Cho, H. E.; Kim, J. H.; Wall, M.; Stern, Y.; Lim, H.; Yoo, S.; Kim, H.-S.; CHA, J.

10.1101/625582 — bioinformatics — Posted on 2020-02-10

2728 Effect of Interpopulation Spike-Timing-Dependent Plasticity on Synchronized Rhythms in Neuronal Networks with Inhibitory and Excitatory Populations

Kim, S.-Y.; Lim, W.

10.1101/576314 — neuroscience — Posted on 2020-02-10

2729 Functional loss of a non-canonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation

Kutscher, L. M.; Okonechnikov, K.; Batora, N. V.; Clark, J.; Silva, P. B. G.; Vouri, M.; van Rijn, S.; Sieber, L.; Statz, B.; Gearhart, M. D.; Mack, N.; Orr, B. A.; Korshunov, A.; Mercier, A. L.; Ayrault, O.; Kool, M.; Bardwell, V. J.; Pfister, S. M.; Northcott, P. A.; Kawauchi, D.

10.1101/2020.02.06.938035 — cancer biology — Posted on 2020-02-10

2730 The circadian clock contributes to the long-term water use efficiency of Arabidopsis

Simon, N. M.; Graham, C. A.; Comben, N. E.; Hetherington, A. M.; Dodd, A. N.

10.1101/583526 — plant biology — Posted on 2020-02-10

2731 Skill Acquisition is Enhanced by Reducing Trial-To-Trial Repetition

Vleugels, L. W.; Swinnen, S. P.; Hardwick, R. M.

10.1101/866046 — neuroscience — Posted on 2020-02-10

2732 Divide et Impera: Identification of Small-Molecule Inhibitors of HCMV Replication Interfering with Dimerization of DNA Polymerase Processivity Factor UL44

Ghassabian, H.; Falchi, F.; Di Antonio, V.; Timmoneri, M.; Mercorelli, B.; Loregian, A.; Palu, G.; Alvisi, G.

10.1101/2020.02.06.938233 — microbiology — Posted on 2020-02-10

2733 Effect of helical kink in antimicrobial peptides on membrane pore formation

Türkova, A.; Kabelka, I.; Kralova, T.; Sukenik, L.; Pokorna, S.; Hof, M.; Vacha, R.

10.1101/641514 — biophysics — Posted on 2020-02-10

2734 Preliminary identification of potential vaccine targets for 2019-nCoV based on SARS-CoV immunological studies

Ahmed, S. F.; Quadeer, A. A.; McKay, M. R.

10.1101/2020.02.03.933226 — bioinformatics — Posted on 2020-02-10

2735 Neural representations of social valence bias economic interpersonal choices

Diaz-Gutierrez, P.; Arco, J. E.; Alguacil, S.; Gonzalez-Garcia, C.; Ruz, M.

10.1101/355115 — neuroscience — Posted on 2020-02-10

2736 JEDI: Circular RNA Prediction based on Junction Encoders and Deep Interaction among Splice Sites

Jiang, J.-Y.; Ju, C. J.-T.; Hao, J.; Chen, M.; Wang, W.

10.1101/2020.02.03.932038 — bioinformatics — Posted on 2020-02-10

2737 Disentangling Decision-related Feedforward and Feedback Signals in Human Cortex

Wilming, N.; Murphy, P. R.; Meyniel, F.; Donner, T. H.

10.1101/2020.02.01.929893 — neuroscience — Posted on 2020-02-10

2738 Measuring Robustness of Brain Networks in Autism Spectrum Disorder with Ricci Curvature

Simhal, A. K.; Carpenter, K. L. H.; Nadeem, S.; Kurtzberg, J.; Song, A.; Tannenbaum, A.; Sapiro, G.; Dawson, G.

10.1101/722025 — neuroscience — Posted on 2020-02-10

2739 An updated antennal lobe atlas for the yellow fever mosquito Aedes aegypti

Shankar, S.; McMeniman, C. J.

10.1101/865675 — neuroscience — Posted on 2020-02-10

2740 Genetic Disruption of Serine Biosynthesis is a Key Driver of Macular Telangiectasia Type 2 Etiology and Progression

Bonelli, R.; Ansell, B.; Lotta, L.; Scerri, T.; Clemons, T. E.; Leung, I.; The MacTel Consortium, ; Peto, T.; Bird, A. C.; Sallo, F.; Langenberg, C.; Bahlo, M.

10.1101/2020.02.04.934356 — genetics — Posted on 2020-02-10

2741 Biocomputational Analysis Establishes Genetic Association of Rheumatoid Arthritis (RA) and Migraine

Roy, N.; Mazumder, A.

10.1101/2020.02.05.936534 — bioinformatics — Posted on 2020-02-10

2742 Genetic characterization of stem cell-like cancer cell in the peri-tumoral regions and proliferative lymphocyte in the peripheral blood of patients with glioblastoma

Yang, R.; Huang, G.; Guo, J.; Li, Y.; Song, H.; Li, K.; Yi, G.; Lin, Z.; Wang, X.; Xie, S.; Liu, Z.; Shi, X.; Li, K.; Qi, S.; Liu, Y.

10.1101/2020.01.06.895987 — cancer biology — Posted on 2020-02-10

2743 Arachidonic acid promotes the binding of 5-lipoxygenase on nanodiscs containing 5-lipoxygenase activating protein in the absence of calcium-ions.

Kumar, R. B.; Purhonen, P.; Hebert, H.; Jegerschöld, C.

10.1101/2020.01.22.915090 — biochemistry — Posted on 2020-02-10

2744 The role of humans on Antillean land vertebrate extinctions: new insights from Cuba

Orihuela, J.; Vinola, L. W.; Jimenez Vazquez, O.; Mychajliw, A.; Hernandez de Lara, O.; Lorenzo, L.; Soto-Centeno, J. A.

10.1101/2020.01.27.922237 — paleontology — Posted on 2020-02-10

2745 Set2-mediated alternative splicing of Srsf11 regulates cocaine reward behavior

Xu, S.-J.; Lombroso, S. I.; Carpenter, M.; Marchione, D. M.; Hamilton, P. J.; Lim, C. J.; Neve, R.; Heller, E. A.

10.1101/798009 — neuroscience — Posted on 2020-02-10

2746 An Autoencoder and Artificial Neural Network-based Method to Estimate Parity Status of Wild Mosquitoes from Near-infrared Spectra

Milali, M. P.; Kiware, S. S.; Govella, N. J.; Okumu, F.; Bansal, N.; Bozdag, S.; Charlwood, J. D.; Maia, M. F.; Ogoma, S. B.; Dowell, F. E.; Corliss, G. F.; Sikulu-Lord, M. T.; Povinelli, R. J.

10.1101/2020.01.25.919878 — bioinformatics — Posted on 2020-02-09

2747 Distinct synchronization, cortical coupling and behavioural function of two basal forebrain cholinergic neuron types

Laszlovszky, T.; Schlingloff, D.; Hegedus, P.; Tamas, F. F.; Gulyas, A.; Kepecs, A.; Hangya, B.

10.1101/703090 — neuroscience — Posted on 2020-02-09

2748 Probing the neural dynamics of mnemonic representations after the initial consolidation

Liu, W.; Kohn, N.; Fernandez, G.

10.1101/803718 — neuroscience — Posted on 2020-02-09

2749 Elucidation of novel miRNA candidates and their role in unraveling the pathology of Non-Alcoholic Fatty Liver Disease

Biju, B. M.; Chhabra, S. S.; Sarkar, C.

10.1101/2020.01.31.917831 — molecular biology — Posted on 2020-02-09

2750 Dissecting heterogeneous cell-populations across drug and disease conditions with PopAlign

Chen, S.; Park, J. H.; Rivaud, P.; Charles, E.; Haliburton, J.; Pichiorri, F.; Thomson, M.

10.1101/421354 — bioinformatics — Posted on 2020-02-09

2751 Simulating bout-and-pause patterns with reinforcement learning

Yamada, K.; Kanemura, A.

10.1101/632745 — animal behavior and cognition — Posted on 2020-02-09

2752 Expression and purification of African Swine Fever virus p72 trimers as subunit vaccine candidate

Meng, K.; Zhang, Y.; Zhu, W.; Xiang, Y.; Meng, G.

10.1101/2020.01.30.926808 — microbiology — Posted on 2020-02-09

2753 Lgr5+ telocytes are a signaling hub at the intestinal villus tip

Bahar Halpern, K.; Massalha, H.; Zwick, R. K.; Moor, A. E.; Castillo-Azofeifa, D.; Rozenberg, M.; Farack, L.; Egozi, A.; Miller, D. R.; Averbukh, I.; Harnik, Y.; Weinberg-Corem, N.; de Sauvage, F. J.; Amit, I.; Klein, O. D.; Shoshkes-Carmel, M.; Itzkovitz, S.

10.1101/850909 — cell biology — Posted on 2020-02-09

2754 Lgr5+ telocytes are a signaling hub at the intestinal villus tip

10.1101/850909 — cell biology — Posted on 2020-02-09

2755 Neural correlates of newsvendor-based decision making in the human brain: An exploratory study to link neuroeconomics with neuroimaging using fNIRS

Wanniarachchi, H.; Lang, Y.; Wang, X.; Nerur, S.; Chen, K. Y.; Liu, H.

10.1101/2020.02.08.940197 — neuroscience — Posted on 2020-02-09

2756 Basal media optimization for the micropropagation and callogenesis of Cannabis sativa L.

Page, S. R. G.; Monthony, A. A. S.; Jones, M.

10.1101/2020.02.07.939181 — plant biology — Posted on 2020-02-09

2757 RNase L amplifies Interferon signaling by inducing PKR-mediated antiviral stress granules

Manivannan, P.; Siddiqui, M. A.; Malathi, K.

10.1101/2020.02.07.939645 — immunology — Posted on 2020-02-09

2758 Engineering Functional Pseudo-Islets of Defined Sizes from Primary Murine Cells Using PEG Microwell Devices

Shekiro, K. T.; Hraha, T. H.; Bernard, A. B.; Benninger, R. K.; Anseth, K. S.

10.1101/2020.02.07.939538 — bioengineering — Posted on 2020-02-09

2759 Developing bio-technical reliability among future researchers and industrial work-force in developing countries: a success story

Acharya, K. K.

10.1101/2020.02.03.919209 — scientific communication and education — Posted on 2020-02-09

2760 DRT111/SFPS splicing factor controls ABA sensitivity in Arabidopsis seed development and germination

Punzo, P.; Ruggiero, A.; Possenti, M.; Perrella, G.; Nurcato, R.; Costa, A.; Morelli, G.; Grillo, S.; Batelli, G.

10.1101/2020.02.07.939421 — plant biology — Posted on 2020-02-09

2761 Understanding the Effect of Left Prefrontal Stimulation on Positive Symptoms of Schizophrenia: A Dynamic Causal Modeling Study of Ultra-high field (7-Tesla) Resting-state fMRI

Limongi, R.; Mackinley, M.; Dempster, K.; Khan, A. R.; Gati, J. S.; PALANIYAPPAN, L.

10.1101/2020.02.07.939470 — neuroscience — Posted on 2020-02-09

2762 Mechanisms of Feature Selectivity and Invariance in Primary Visual Cortex

Almasi, A.; Meffin, H.; Cloherty, S.; Wong, Y. T.; Yunzab, M.; Ibbotson, M. R.

10.1101/2020.02.08.940270 — neuroscience — Posted on 2020-02-09

2763 Chemogenetic stimulation of mouse central amygdala corticotropin-releasing factor neurons: Effects on cellular and behavioral correlates of alcoholdependence

Kreifeldt, M.; Herman, M. A.; Sidhu, H.; de Macedo, G. C.; Shahryari, R.; Roberto, M.; Contet, C.

10.1101/2020.02.07.939496 — neuroscience — Posted on 2020-02-09

2764 Vascular-Derived SPARC and SerpinE1 Regulate Interneuron Tangential Migration and Accelerate Functional Maturation of Human Stem Cell-Derived Interneurons

Genestine, M.; Ambriz, D.; Crabtree, G. W.; Molotkova, A.; Quintero, M.; Mela, A.; Biswas, S.; Canoll, P.; Hargus, G.; Agalliu, D.; Gogos, J. A.; Au, E.

10.1101/2020.02.07.939298 — neuroscience — Posted on 2020-02-09

2765 Distinct Hierarchical Alterations of Intrinsic Neural Timescales Account for Different Manifestations of Psychosis

Wengler, K.; Goldberg, A.; Chahine, G.; Horga, G.

10.1101/2020.02.07.939520 — neuroscience — Posted on 2020-02-09

2766 Comparison between conventional electrodes and ultrasound monitoring to measure TMS evoked muscle contraction

Kaczmarczyk, I.; Rawji, V.; Rothwell, J. C.; Hodson-Tole, E. F.; Sharma, N.

10.1101/2020.02.07.938837 — neuroscience — Posted on 2020-02-09

2767 Imaging Microglia and Astrocytes non-invasively using Diffusion MRI

Garcia-Hernandez, R.; Trouve Carpena, A.; Drakesmith, M.; Koller, K.; Jones, D. K.; Canals, S.; De Santis, S.

10.1101/2020.02.07.938910 — neuroscience — Posted on 2020-02-09

2768 Improving model-based fNIRS analysis using mesh-based anatomical and light-transport models

Tran, A. P.; Yan, S.; Fang, Q.

10.1101/2020.02.07.939447 — neuroscience — Posted on 2020-02-09

2769 Decoding Attention Control and Selection in Visual Spatial Attention

Hong, X.; Bo, K.; Meyyapan, S.; Tong, S.; Ding, M.

10.1101/2020.02.08.940213 — neuroscience — Posted on 2020-02-09

2770 Inhibiting LXRα Phosphorylation in Hematopoietic Cells Reduces Inflammation and Attenuates Atherosclerosis and Obesity

Voisin, M.; Shrestha, E.; Rollet, C.; Josefs, T.; Barrett, T. J.; Chang, H. R.; Ruoff, R.; Nikain, C. A.; Garabedian, M. L.; Brown, E. J.; Goldberg, I. J.; Pineda-Torra, I.; Fisher, E. A.; Garabedian, M.

10.1101/2020.02.07.939090 — molecular biology — Posted on 2020-02-09

2771 Polymorphisms in human APOBEC3H differentially regulate ubiquitination and antiviral activity

Chesarino, N. M.; Emerman, M.

10.1101/2020.02.07.939439 — microbiology — Posted on 2020-02-09

2772 A comprehensive co-expression network analysis in Vibrio cholerae

DuPai, C. D.; Wilke, C. O.; Davies, B. W.

10.1101/2020.02.07.939611 — microbiology — Posted on 2020-02-09

2773 High precision Neisseria gonorrhoeae variant and antimicrobial resistance calling from metagenomic Nanopore sequencing

Sanderson, N. D.; Swann, J.; Barker, L.; Kavanagh, J.; Hoosdally, S.; Crook, D.; the GonFast Investigators Group, ; Street, T. L.; Eyre, D. W.

10.1101/2020.02.07.939322 — microbiology — Posted on 2020-02-09

2774 Single cell mutational profiling delineates clonal trajectories in myeloid malignancies

Miles, L. A.; Bowman, R. L.; Merlinsky, T. R.; Csete, I. S.; Ooi, A.; Durruthy-Durruthy, R.; Bowman, M.; Famulare, C.; Patel, M. A.; Mendez, P.; Ainali, C.; Manivannan, M.; Sahu, S.; Goldberg, A. D.; Bolton, K.; ZEHIR, A.; Rampal, R.; Carroll, M. P.; Meyer, S. E.; Viny, A. D.; Levine, R. L.

10.1101/2020.02.07.938860 — cancer biology — Posted on 2020-02-09

2775 Exploring the selenium-over-sulfur substrate specificity and kinetics of a bacterial selenocysteine lyase

Johnstone, M. A.; Nelson, S. J.; Groesbeck, C. V.; Self, W. T.

10.1101/2020.02.07.939272 — biochemistry — Posted on 2020-02-09

2776 Potential G-quadruplex forming sequences and N6-methyladenosine colocalize at human pre-mRNA intron splice sites

Jara-Espejo, M.; Fleming, A. M.; Burrows, C. J.

10.1101/2020.02.07.939116 — biochemistry — Posted on 2020-02-09

2777 The Habitat Amount Hypothesis implies negative effects of habitat fragmentation on species richness and occurrence

Saura, S.

10.1101/2020.02.02.930784 — ecology — Posted on 2020-02-09

2778 RNP-MaP: In-cell analysis of protein interaction networks defines functional hubs in RNA

Weidmann, C. A.; Mustoe, A. M.; Jariwala, P. B.; Calabrese, J. M.; Weeks, K. M.

10.1101/2020.02.07.939108 — biochemistry — Posted on 2020-02-09

2779 Model-based analysis of polymorphisms in an enhancer reveals cis-regulatory mechanisms

Khajouei, F.; Samper, N.; Djabrayan, N. J.- V.; Lunt, B.; Jimenez, G.; Sinha, S.

10.1101/2020.02.07.939264 — bioinformatics — Posted on 2020-02-09

2780 Epidynamics characterize and navigate the map of seizure dynamics

Saggio, M.; Crisp, D.; Scott, J. M.; Karoly, P.; Kuhlmann, L.; Nakatani, M.; Murai, T.; Duempelmann, M.; Schulze-Bonhage, A.; Ikeda, A.; Cook, M.; Gliske, S. V.; Lin, J.; Bernard, C.; Jirsa, V.; Stacey, W. C.

10.1101/2020.02.08.940072 — bioinformatics — Posted on 2020-02-09

2781 WorldFlora: An R package for exact and fuzzy matching of plant names against the World Flora Online Taxonomic Backbone data

Kindt, R.

10.1101/2020.02.02.930719 — plant biology — Posted on 2020-02-09

2782 KIX8 and KIX9 are conserved repressors of organ size in the asterid species tomato

Swinnen, G.; Baekelandt, A.; De Clercq, R.; Van Doorsselaere, J.; Gonzalez, N.; Inze, D.; Goossens, A.; Pauwels, L.

10.1101/2020.02.07.938977 — plant biology — Posted on 2020-02-09

2783 Linear Embodied Saliency: a Model of Full-Body Kinematics-based Visual Attention

Abbott, W. W.; Harston, J. A.; Faisal, A. A.

10.1101/2020.02.08.938514 — neuroscience — Posted on 2020-02-09

2784 Antisense ncRNAs during early vertebrate development are divided in groups with distinct features

Pillay, S.; Takahashi, H.; Carninci, P.; Kanhere, A.

10.1101/2020.02.08.940148 — genomics — Posted on 2020-02-09

2785 Inferring Models with Alternative Stable States from Independent Observations

Tekwa, E. W.; Krkosek, M.; Pinsky, M. L.

10.1101/2020.02.07.939413 — ecology — Posted on 2020-02-09

2786 High-fidelity base editor with no detectable genome-wide off-target effects

Zuo, E.; Sun, Y.; Yuan, T.; He, B.; Zhou, C.; Ying, W.; Liu, J.; Wei, W.; Zeng, R.; Li, Y.; Yang, H.

10.1101/2020.02.07.939074 — genomics — Posted on 2020-02-09

2787 Amplification-free long read sequencing reveals unforeseen CRISPR-Cas9 off-target activity

Höijer, I.; Johansson, J.; Gudmundsson, S.; Chin, C.-S.; Bunikis, I.; Häggqvist, S.; Emmanouilidou, A.; Wilbe, M.; den Hoed, M.; Bondeson, M.-L.; Feuk, L.; Gyllensten, U.; Ameur, A.

10.1101/2020.02.09.940486 — genomics — Posted on 2020-02-09

2788 Leveraging functional annotation to identify genes associated with complex diseases

Liu, W.; Li, M.; Zhang, W.; Zhou, G.; Wu, X.; Wang, J.; Zhao, H.

10.1101/529297 — genetics — Posted on 2020-02-09

2789 Domestication reprogrammed the budding yeast life cycle

De Chiara, M.; Barre, B. P.; Persson, K.; Onyetuga Chioma, A.; Irizar, A.; Warringer, J.; Liti, G.

10.1101/2020.02.08.939314 — evolutionary biology — Posted on 2020-02-09

2790 Reference-free reconstruction and quantification of transcriptomes from long-read sequencing

de la Rubia, I.; Indi, J. A.; Carbonell, S.; Lagarde, J.; Alba, M. M.; Eyras, E.

10.1101/2020.02.08.939942 — bioinformatics — Posted on 2020-02-09

2791 Comparison of High-Throughput Single-Cell RNA Sequencing Data Processing Pipelines

Gao, M.; Ling, M.; Tang, X.; Wang, S.; Xiao, X.; Qiao, Y.; Yang, W.; Yu, R.

10.1101/2020.02.09.940221 — bioinformatics — Posted on 2020-02-09

2792 A non-invasive eDNA tool for detecting sea lamprey larvae in river sediments: analytical validation and field testing in a low abundance ecosystem

Baltazar-Soares, M.; Pinder, A. C.; Harrison, A. J.; Oliver, W.; Picken, J.; Britton, J. R.; Andreou, D.

10.1101/2020.02.08.938803 — genetics — Posted on 2020-02-09

2793 Collective sperm movements are shaped by post-copulatory sexual selection and phylogenetic history in Peromyscus mice

Hook, K. A.; Weber, W. D.; Fisher, H. S.

10.1101/2020.02.08.939975 — evolutionary biology — Posted on 2020-02-09

2794 ARF suppresses 5'-terminal oligopyrimidine mRNA translation

Cottrell, K. A.; Chiou, R. C.; Weber, J. D.

10.1101/2020.02.07.939165 — cell biology — Posted on 2020-02-09

2795 Batch Equalization with a Generative Adversarial Network

Qian, W. W.; Xia, C.; Venugopalan, S.; Narayanaswamy, A.; Peng, J.; Ando, D. M.

10.1101/2020.02.07.939215 — cell biology — Posted on 2020-02-09

2796 Active force generation shapes the metaphase spindle through a mechanical instability

Oriola, D.; Julicher, F.; Brugues, J.

10.1101/2020.02.08.939868 — biophysics — Posted on 2020-02-09

2797 Intra-articular AAV-PHP.S mediated chemogenetic targeting of knee-innervating DRG neurons alleviates inflammatory pain in mice

Chakrabarti, S.; Pattison, L. A.; Doleschall, B.; Rickman, R.; Callejo, G.; Heppenstall, P. A.; Smith, E. S. J.

10.1101/2020.02.08.939066 — neuroscience — Posted on 2020-02-09

2798 Boosting the biogenesis and secretion of mesenchymal stem cell-derived exosomes

Wang, J.; Bonacquisti, E. E.; Nguyen, J.

10.1101/2020.02.08.940122 — cell biology — Posted on 2020-02-09

2799 Deficiency of Norepinephrine Transmission In Brain Contributed To Seizure-Induced Respiratory Arrest And Is Implicated in ADHD with SUDEP In DBA/1 mice

Shen, Y.; MA, H.; Lu, H.; Zhao, H.; Sun, J.; Cheng, Y.; Shen, Y.; Zhou, Y. D.; Zhang, H.

10.1101/865691 — neuroscience — Posted on 2020-02-09

2800 Improved design and analysis of practical minimizers

Zheng, H.; Kingsford, C.; Marcais, G.

10.1101/2020.02.07.939025 — bioinformatics — Posted on 2020-02-09

2801 BOSS-RUNS: a flexible and practical dynamic read sampling framework for nanopore sequencing

De Maio, N.; Manser, C.; Munro, R.; Birney, E.; Loose, M.; Goldman, N.

10.1101/2020.02.07.938670 — genomics — Posted on 2020-02-09

2802 Unsupervised Topological Alignment for Single-Cell Multi-Omics Integration

Cao, K.; Bai, X.; Hong, Y.; Wan, L.

10.1101/2020.02.02.931394 — bioinformatics — Posted on 2020-02-09

2803 Preliminary identification of potential vaccine targets for 2019-nCoV based on SARS-CoV immunological studies

Ahmed, S. F.; Quadeer, A. A.; McKay, M. R.

10.1101/2020.02.03.933226 — bioinformatics — Posted on 2020-02-09

2804 Transfer learning enables prediction of CYP2D6 haplotype function

McInnes, G.; Dalton, R.; Sangkuhl, K.; Whirl-Carrillo, M.; Lee, S.-b.; Altman, R. B.; Woodahl, E. L.

10.1101/684357 — bioinformatics — Posted on 2020-02-09

2805 Bipartite Tight Spectral Clustering (BiTSC) Algorithm for Identifying Conserved Gene Co-clusters in Two Species

Sun, Y.; Zhou, H.; Li, J. J.

10.1101/865378 — bioinformatics — Posted on 2020-02-09

2806 Machine learning analysis of genomic signatures provides evidence of associations between Wuhan 2019-nCoV and bat betacoronaviruses

Randhawa, G. S.; Soltysiak, M. P. M.; El Roz, H.; de Souza, C. P. E.; Hill, K. A.; Kari, L.

10.1101/2020.02.03.932350 — bioinformatics — Posted on 2020-02-09

2807 Improvement of glymphatic-lymphatic drainage of beta-amyloid by focused ultrasound in Alzheimer's disease model

Lee, Y.; Choi, Y.; Park, E.-J.; Kwon, S.; Kim, H.; Lee, J. Y.; Lee, D. S.

10.1101/2020.01.24.918607 — neuroscience — Posted on 2020-02-09

2808 Diminished cortical excitation and elevated inhibition during perceptual impairments in a mouse model of autism

Del Rosario, J.; Speed, A.; Arrowood, H.; Motz, C.; Pardue, M.; Haider, B.

10.1101/657189 — neuroscience — Posted on 2020-02-09

2809 Game Theory Applications in Host-Microbe Interactions: Mycobacterium tuberculosis infection as an example

Sharebiani, H.; Hajimiri, S.; Abbasnia, S.; Soleimanpour, S.; Asnaashari, A. M. H.; Valizadeh, N.; Derakhshan, M.; Pilpa, R.; Firouzeh, A.; Ghazvini, K.; Amel Jamehdar, S.; Rezaee, S. A. R.

10.1101/2019.12.26.888602 — microbiology — Posted on 2020-02-09

2810 Dissecting heterogeneous cell-populations across drug and disease conditions with PopAlign

Chen, S.; Park, J. H.; Rivaud, P.; Charles, E.; Haliburton, J.; Pichiorri, F.; Thomson, M.

10.1101/421354 — bioinformatics — Posted on 2020-02-09

2811 Lack of selectivity for syntax relative to word meanings throughout the language network

Fedorenko, E.; Blank, I.; Siegelman, M.; Mineroff, Z.

10.1101/477851 — neuroscience — Posted on 2020-02-09

2812 Ubiquitination and Phosphorylation are Independently Required for Epsin-Mediated Internalization of Cargo in S. cerevisiae

Sen, A.; Hsieh, W.-C.; Hanna, C. B.; Hsu, C.-C.; Pearson, M.; Tao, A.; Aguilar, R. C.

10.1101/2020.02.07.939082 — cell biology — Posted on 2020-02-08

2813 A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies

Borden, P. M.; Zhang, P.; Shivange, A. V.; Marvin, J. S.; Cichon, J.; Dan, C.; Podgorski, K.; Figueiredo, A.; Novak, O.; Tanimoto, M.; Shigetomi, E.; Lobas, M. A.; Kim, H.; Zhu, P. K.; Zhang, Y.; Zheng, W. S.; Fan, C.; Wang, G.; Xiang, B.; Gan, L.; Zhang, G.-X.; Guo, K.; Lin, L.; Cai, Y.; Yee, A.; Aggarwal, A.; Ford, C. P.; Rees, D. C.; Dietrich, D.; KHAKH, B. S.; Dittman, J. S.; Gan, W.-B.; Koyama, M. S.; Jayaraman, V.; Cheer, J. F.; Lester, H. A.; Zhu, J. J.; Looger, L. L.

10.1101/2020.02.07.939504 — neuroscience — Posted on 2020-02-08

2814 A novel role for cortical acetylcholine in object memory updating

Jardine, K. H.; Wideman, C. E.; MacGregor, C.; Sgarbossa, C.; Orr, D.; Mitchnick, K. A.; Winters, B. D.

10.1101/2020.02.08.940064 — neuroscience — Posted on 2020-02-08

2815 Metagenomics workflow for hybrid assembly, differential coverage binning, transcriptomics and pathway analysis (MUFFIN)

Van Damme, R.; Hölzer, M.; Viehweger, A.; Müller, B.; Bongcam-Rudloff, E.; Brandt, C.

10.1101/2020.02.08.939843 — bioinformatics — Posted on 2020-02-08

2816 Genomic signals found using RNA sequencing support conservation of walleye (Sander vitreus) in a large freshwater ecosystem.

Thorstensen, M. J.; Jeffrey, J. D.; Treberg, J. R.; Watkinson, D. A.; Enders, E. C.; Jeffries, K. M.

10.1101/2020.02.07.937961 — genomics — Posted on 2020-02-08

2817 Genetic Adaptation in New York City Rats

Harpak, A.; Garud, N.; Rosenberg, N. A.; Petrov, D. A.; Combs, M.; Pennings, P. S.; Munshi-South, J.

10.1101/2020.02.07.938969 — evolutionary biology — Posted on 2020-02-08

2818 Economic Genome Assembly from Low Coverage Illumina and Nanopore Data

Gatter, T.; von Loehneysen, S.; Drozdova, P.; Hartmann, T.; Stadler, P. F.

10.1101/2020.02.07.939454 — bioinformatics — Posted on 2020-02-08

2819 Modeling and analysis of site-specific mutations in cancer identifies known plus putative novel hotspots and bias due to contextual sequences

TREVINO, V.

10.1101/2020.02.07.939512 — bioinformatics — Posted on 2020-02-08

2820 Negative selection on human genes causing severe inborn errors depends on disease outcome and both the mode and mechanism of inheritance

Rapaport, F.; Boisson, B.; Gregor, A.; Beziat, V.; Boisson-Dupuis, S.; Bustamante, J.; Jouanguy, E.; Puel, A.; Rosain, J.; Zhang, Q.; Zhang, S.-Y.; Gleeson, J.; Quintana-Murci, L.; Casanova, J.-L.; Abel, L.; Patin, E.

10.1101/2020.02.07.938894 — genetics — Posted on 2020-02-08

2821 Protein structure and sequence re-analysis of 2019-nCoV genome does not indicate snakes as its intermediate host or the unique similarity between its spike protein insertions and HIV-1

Zhang, C.; Zheng, W.; Huang, X.; Bell, E. W.; Zhou, X.; Zhang, Y.

10.1101/2020.02.04.933135 — bioinformatics — Posted on 2020-02-08

2822 Tumor Phylogeny Topology Inference via Deep Learning

Sadeqi Azer, E.; Haghir Ebrahimabadi, M.; Malikic, S.; Khardon, R.; Sahinalp, S. C.

10.1101/2020.02.07.938852 — bioinformatics — Posted on 2020-02-08

2823 The integration of Gaussian noise by long-range amygdala inputs in frontal circuit promotes fear learning

Aime, M.; Augusto, E.; Kouskoff, V.; Martin, C.; Humeau, Y.; Chenouard, N.; Gambino, F.

10.1101/569137 — neuroscience — Posted on 2020-02-08

2824 Dissecting heterogeneous cell-populations across signaling and disease conditions with PopAlign

Chen, S.; Park, J. H.; Rivaud, P.; Charles, E.; Haliburton, J.; Pichiorri, F.; Thomson, M.

10.1101/421354 — bioinformatics — Posted on 2020-02-08

2825 Analysis of translating mitoribosome reveals functional characteristics of protein synthesis in mitochondria of fungi

Naschberger, A.; Itoh, Y.; Mortezaei, N.; Herrmann, J.; Amunts, A.

10.1101/2020.01.31.929331 — biochemistry — Posted on 2020-02-08

2826 The role of humans on Antillean land vertebrate extinctions: new insights from Cuba

Orihuela, J.; Vinola, L. W.; Jimenez Vazquez, O.; Mychajliw, A.; Hernandez de Lara, O.; Lorenzo, L.; Soto-Centeno, J. A.

10.1101/2020.01.27.922237 — paleontology — Posted on 2020-02-08

2827 Expression and purification of African Swine Fever virus p72 trimers as subunit vaccine candidate

Meng, K.; Zhang, Y.; Zhu, W.; Xiang, Y.; Meng, G.

10.1101/2020.01.30.926808 — microbiology — Posted on 2020-02-08

2828 Kinetics of Plasmodium midgut invasion in Anopheles mosquitoes

Volohonsky, G.; Paul-Gilloteaux, P.; Stafkova, J.; Soichot, J.; Salamero, J.; Levashina, E. A.

10.1101/2020.02.06.937276 — immunology — Posted on 2020-02-08

2829 A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism.

10.1101/2020.01.06.896258 — genomics — Posted on 2020-02-08

2830 Genetic Disruption of Serine Biosynthesis is a Key Driver of Macular Telangiectasia Type 2 Etiology and Progression

Bonelli, R.; Ansell, B.; Lotta, L.; Scerri, T.; Clemons, T. E.; Leung, I.; The MacTel Consortium, ; Peto, T.; Bird, A. C.; Sallo, F.; Langenberg, C.; Bahlo, M.

10.1101/2020.02.04.934356 — genetics — Posted on 2020-02-08

2831 Neural correlates of social variation in coral reef butterflyfishes

Nowicki, J.; Pratchett, M.; Coker, D.; Walker, S.; O'Connell, L. A.

10.1101/214759 — neuroscience — Posted on 2020-02-08

2832 Habitat affinity and density-dependent movement as indicators of fish habitat restoration efficacy

Polivka, C.

10.1101/712935 — ecology — Posted on 2020-02-08

2833 Beyond redistribution: In-stream habitat restoration increases capacity for young-of-the-year Chinook salmon and steelhead in the Entiat River, WA

Polivka, C.; Claeson, S. M.

10.1101/665604 — ecology — Posted on 2020-02-08

2834 Biophysical models of cis-regulation as interpretable neural networks

Tareen, A.; Kinney, J. B.

10.1101/835942 — bioinformatics — Posted on 2020-02-08

2835 C. elegans aversive olfactory learning generates diverse intergenerational effects

Pereira, A.; Gracida, X.; Kagias, K.; Zhang, Y.

10.1101/2020.02.07.939017 — neuroscience — Posted on 2020-02-08

2836 Canopy position has a stronger effect than tree species identity on phyllosphere bacterial diversity in a floodplain hardwood forest

Herrmann, M.; Geesink, P.; Richter, R.; Kuesel, K.

10.1101/2020.02.07.939058 — microbiology — Posted on 2020-02-08

2837 Mitochondria dynamics in postmitotic cells drives neurogenesis through Sirtuin-dependent chromatin remodeling.

Iwata, R.; Vanderhaeghen, P.

10.1101/2020.02.07.938985 — neuroscience — Posted on 2020-02-08

2838 The Ph.D. Panic: Examining the relationships among teaching anxiety, teaching self-efficacy, and coping in Biology graduate teaching assistants (GTAs)

Chen Musgrove, M. M.; Schussler, E. E.

10.1101/2020.02.07.938597 — scientific communication and education — Posted on 2020-02-07

2839 SPAs promote thermomorphogenesis via regulating the phyB-PIF4 module in Arabidopsis

Lee, S.; Paik, I.; Huq, E.

10.1101/2020.02.07.938951 — plant biology — Posted on 2020-02-07

2840 The haemodynamics of the human placenta in utero

Dellschaft, N. S.; Hutchinson, G.; Shah, S.; Jones, N. W.; Bradley, C.; Leach, L.; Platt, C.; Bowtell, R.; Gowland, P.

10.1101/2020.02.07.938589 — physiology — Posted on 2020-02-07

2841 Markers of Acute Toxicity in Pancreatic Beta-Cells Exposed to Lethal Doses of the Organochlorine Pollutant DDT Determined by a Proteomic Approach

Pavlikova, N.; Sramek, J.; Jelinek, M.; Halada, P.; Kovar, J.

10.1101/2020.02.07.938605 — pharmacology and toxicology — Posted on 2020-02-07

2842 A Novel Performance Metric for Multiclass Subject Invariant Brain Computer Interfaces with Imbalanced Classes

Sherwood, J.; Lowe, J.; Derakhshani, R.

10.1101/2020.02.07.938548 — neuroscience — Posted on 2020-02-07

2843 SCRINSHOT, a spatial method for single-cell resolution mapping of cell states in tissue sections

Sountoulidis, A.; Liontos, A.; Nguyen, H. P.; Firsova, A. B.; Fysikopoulos, A.; Qian, X.; Seeger, W.; Sundström, E.; Nilsson, M.; Samakovlis, C.

10.1101/2020.02.07.938571 — molecular biology — Posted on 2020-02-07

2844 Nanobody mediated neutralization reveals an Achilles heel for norovirus

Koromyslova, A. D.; Devant, J. M.; Kilic, T.; Sabin, C.; Malak, V.; Hansman, G. S.

10.1101/2020.02.07.938506 — molecular biology — Posted on 2020-02-07

2845 A novel factor essential for unconventional secretion of chitinase Cts1

Reindl, M.; Stock, J.; Hussnaetter, K. P.; Genc, A.; Brachmann, A.; Schipper, K.

10.1101/2020.02.07.938613 — microbiology — Posted on 2020-02-07

2846 On the preservation of vessel bifurcations during flow-mediated angiogenic remodelling

Edgar, L. T.; Franco, C. A.; Gerhardt, H.; Bernabeu, M. O.

10.1101/2020.02.07.938522 — cell biology — Posted on 2020-02-07

2847 Snow Microbiome Functional Analyses Reveal Novel Microbial Metabolism of Complex Organic Compounds

Zhu, C.; Miller, M.; Lusskin, N.; Bergk Pinto, B.; Maccario, L.; Haggblom, M.; Vogel, T.; Larose, C.; Bromberg, Y.

10.1101/2020.02.07.938555 — bioinformatics — Posted on 2020-02-07

2848 Improved design and analysis of practical minimizers

Zheng, H.; Kingsford, C.; Marcais, G.

10.1101/2020.02.07.939025 — bioinformatics — Posted on 2020-02-07

2849 The acetyltransferase Eco1 elicits cohesin dimerization during S phase

Shi, D.; Zhao, S.; Zuo, M.-Q.; Zhang, J.; Hou, W.; Dong, M.; Cao, Q.; Lou, H.

10.1101/2020.02.07.938530 — biochemistry — Posted on 2020-02-07

2850 In Vitro Assessment of Antioxidant activity, Antimicrobial, and cytotoxicity of ultrasound-assisted acetone extracts of Plectranthus amboinicus

Ye, X.

10.1101/2020.02.07.938928 — pharmacology and toxicology — Posted on 2020-02-07

2851 The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells

Hodgkinson, T.; Tsimbouri, M.; Llopis-Hernandez, V.; Campsie, P.; Scurr, D.; Childs, P.; Phillips, D.; Donnelly, S.; Wells, J.; Salmeron-Sanchez, M.; Burgess, K.; Alexander, M. R.; Vassalli, M.; Oreffo, R.; Reid, S. R.; France, D.; Dalby, M. J.

10.1101/2020.02.07.938811 — bioengineering — Posted on 2020-02-07

2852 Phosphoproteomic analysis of mammalian infective Trypanosoma brucei subjected to heat shock suggests atypical mechanisms for thermotolerance

Ooi, C. P.; Benz, C.; Urbaniak, M. D.

10.1101/2020.02.07.938761 — cell biology — Posted on 2020-02-07

2853 Physiological and Metabolic Features of Mice with CRISPR/Cas9-Mediated Loss-of-Function in Growth Hormone-Releasing Hormone

Zhang, F.; Liou, S. Y.; Challa, A. K.; Fitch, M. P.; Icyuz, M.

10.1101/2020.02.07.937789 — physiology — Posted on 2020-02-07

2854 Cold-mediated regulation of systemic retinol transport controls adipose tissue browning

Fenzl, A.; Kulterer, O. C.; Spirk, K.; Mitulovic, G.; Marculescu, R.; Bilban, M.; Baumgartner-Parzer, S.; Kautzky-Willer, A.; Kenner, L.; Plutzky, J.; Quadro, L.; Kiefer, F. W.

10.1101/2020.02.07.938688 — physiology — Posted on 2020-02-07

2855 Characterization of the motor cortex transcriptome supports microgial-related key events in amyotrophic lateral sclerosis

Dols-Icardo, O.; Montal, V.; Sirisi, S.; Lopez-Pernas, G.; Cervera-Carles, L.; Querol-Vilaseca, M.; Munoz, L.; Belbin, O.; Alcolea, D.; Molina-Porcel, L.; Pegueroles, J.; Turon-Sans, J.; Blesa, R.; Lleo, A.; Fortea, J.; Rojas-Garcia, R.; Clarimon, J.

10.1101/2020.02.07.938662 — neuroscience — Posted on 2020-02-07

2856 Translate the untranslated: excising as a novel post-splicing event

Panteleev, D. Y.; Reshetnikov, R. V.; Samoylenkova, N. S.; Pustogarov, N. A.; Pavlova, G. V.

10.1101/2020.02.07.938738 — molecular biology — Posted on 2020-02-07

2857 Phasing and imputation of single nucleotide polymorphism data of missing parents of bi-parental plant populations

Gonen, S.; Wimmer, V.; Gaynor, C.; Byrne, E.; Gorjanc, G.; Hickey, J. M.

10.1101/2020.02.07.938795 — genetics — Posted on 2020-02-07

2858 Bumblebee worker castes show differences in allele-specific DNA methylation and allele-specific expression.

Marshall, H.; Jones, A. R. C.; Lonsdale, Z. N.; Mallon, E. B.

10.1101/2020.02.07.938423 — evolutionary biology — Posted on 2020-02-07

2859 Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell Genomics

Morita, K.; Wang, F.; Jahn, K.; Kuipers, J.; Yan, Y.; Matthews, J.; Little, L.; Gumbs, C.; Chen, S.; Zhang, J.; Song, X.; Thompson, E.; Patel, K.; Bueso-Ramos, C.; DiNardo, C. D.; Ravandi, F.; Jabbour, E.; Andreeff, M.; Cortes, J.; Konopleva, M.; Bhalla, K.; Garcia-Manero, G.; Kantarjian, H.; Beerenwinkel, N.; Navin, N.; Futreal, P. A.; Takahashi, K.

10.1101/2020.02.07.925743 — cancer biology — Posted on 2020-02-07

2860 Dual blockade of IL-6 and CTLA-4 regresses pancreatic tumors in a CD4+ T cell-dependent manner.

Ware, M. B.; McQuinn, C.; Zaidi, M. Y.; Knochelmann, H.; Mace, T. A.; Chen, Z.; Zhang, C.; Farren, M. R.; Ruggieri, A. N.; Bowers, J.; Shakya, R.; Farris, A. B.; Young, G.; Carson, W. E.; El-Rayes, B.; Paulos, C. M.; Lesinski, G. B.

10.1101/2020.02.07.939199 — cancer biology — Posted on 2020-02-07

2861 DNA Methylation Repels Binding of HIF Transcription Factors to Maintain Tumour Immunotolerance

D'Anna, F.; Van Dyck, L.; Xiong, J.; Zhao, H.; Berrens, R.; De Smedt, J.; Bieniasz-Krzywiec, P.; Chandra, V.; Schoonjans, L.; Matthews, J.; Minnoye, L.; Qian, J.; Amorim, R.; Khorasanizadeh, S.; De Borre, M.; Savvides, S. N.; Simon, C.; Carmeliet, P.; Reik, W.; Rastinejad, F.; Mazzone, M.; Thienpont, B.; Lambrechts, D.

10.1101/2020.02.07.931071 — genomics — Posted on 2020-02-07

2862 Familial primary ovarian insufficiency associated with a SYCE1 point mutation: Defective meiosis elucidated in humanized mice

Hernandez-Lopez, D.; Geisinger, A.; Trovero, M. F.; Santinaque, F. F.; Brauer, M.; Folle, G. A.; Benavente, R.; Rodriguez-Casuriaga, R.

10.1101/2020.02.07.938639 — genetics — Posted on 2020-02-07

2863 A 3D human liver model of nonalcoholic steatohepatitis

Duriez, M.; Hoet, L.; Jacquet, A.; Roche, S.; Bock, M.-D.; Rocher, C.; Haussy, G.; Vige, X.; Bocskei, Z.; Slavnic, T.; Martin, V.; Guillemot, J.-C.; Didier, M.; Kannt, A.; Orsini, C.; Mikol, V.; Le Fevre, A.-C.

10.1101/2020.02.07.938787 — cell biology — Posted on 2020-02-07

2864 Sparse latent factor regression models for genome-wide and epigenome-wide association studies

Jumentier, B.; Caye, K.; Heude, B.; Lepeule, J.; Francois, O.

10.1101/2020.02.07.938381 — bioinformatics — Posted on 2020-02-07

2865 Genetic basis of phenotypic plasticity and genotype x environment interaction in a multi-parental population

Diouf, I. A.; Derivot, L.; Koussevitzky, S.; Carretero, Y.; Bitton, F.; Moreau, L.; Causse, M.

10.1101/2020.02.07.938456 — plant biology — Posted on 2020-02-07

2866 Large home range scavengers support higher rates of carcass removal

Gutierrez-Canovas, C.; Moleon, M.; Mateo-Tomas, P.; Olea, P. P.; Sebastian-Gonzalez, E.; Sanchez-Zapata, J. A.

10.1101/2020.02.07.938415 — ecology — Posted on 2020-02-07

2867 Loss of epithelial polarity redirects Notch signaling and triggers a Xrp1 response during neoplastic growth in Drosophila

Logeay, R.; Geminard, C.; Lassus, P.; Kantar, D.; Heron-Milhavet, L.; Fischer, B.; Bray, S. J.; Colinge, J.; Djiane, A.

10.1101/2020.02.07.938621 — developmental biology — Posted on 2020-02-07

2868 Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres

Loe, T. K.; Li, J.; Zhang, Y.; Azeroglu, B.; Boddy, M. N.; Lazzerini Denchi, E.

10.1101/2020.02.07.938753 — cancer biology — Posted on 2020-02-07

2869 Prochlorococcus phage ferredoxin: structural characterization and interactions with cyanobacterial sulfite reductases

Campbell, I. J.; Olmos, J. L.; Xu, W.; Kahanda, D.; Atkinson, J. T.; Sparks, O. N.; Miller, M. D.; Phillips, G. N.; Bennett, G. N.; Silberg, J. J.

10.1101/2020.02.07.937771 — biochemistry — Posted on 2020-02-07

2870 Two parallel pathways convey distinct visual information to the Drosophila mushroom body

Caron, S. J. C.; Li, J.; Mahoney, B. D.; Jacob, M. S.

10.1101/2020.02.07.935924 — neuroscience — Posted on 2020-02-07

2871 Large extracellular vesicles can be characterised by multiplex labelling using imaging flow cytometry

Johnson, S. M.; Banyard, A.; Smith, C.; Mironov, A.; McCabe, M. G.

10.1101/2020.02.07.938779 — cell biology — Posted on 2020-02-07

2872 The Nef protein of the macrophage tropic HIV-1 strain AD8 counteracts human Bst-2/tetherin

Giese, S.; Lawrence, S. P.; Mazzon, M.; Nijmeijer, B. M.; Marsh, M.

10.1101/2020.02.07.938464 — cell biology — Posted on 2020-02-07

2873 Depletion of glycosaminoglycans decreases contact stiffness of single collagen I fibrils in aqueous solution

Roth, J. A.; Hoop, C.; Williams, J.; Hayes, R.; Baum, J.

10.1101/2020.02.07.935932 — biophysics — Posted on 2020-02-07

2874 Subfield-specific Effects of Chronic Mild Unpredictable Stress on Hippocampal Astrocytes

Virmani, G.; D'almeida, P.; Nandi, A.; Marathe, S.

10.1101/2020.02.07.938472 — neuroscience — Posted on 2020-02-07

2875 Widespread Recombination Suppression Facilitates Plant Sex Chromosome Evolution

Rifkin, J. L.; Beaudry, F. L.; Humphries, Z.; Choudhury, B. I.; Barrett, S. C. H.; Wright, S. I.

10.1101/2020.02.07.937490 — evolutionary biology — Posted on 2020-02-07

2876 Augmenting Vascular Disease Diagnosis by Vasculature-awareUnsupervised Learning

WANG, Y.; JI, M.; JIANG, S.; WANG, X.; WU, J.; DUAN, F.; FAN, J.; HUANG, L.; MA, S.; FANG, L.; DAI, Q.

10.1101/2020.02.07.938282 — bioengineering — Posted on 2020-02-07

2877 Assessment of different seedling production techniques of Euterpe edulis

Regnier, L. d. L. P.; Salatino, M. F.

10.1101/2020.02.07.937755 — plant biology — Posted on 2020-02-07

2878 Interaction of the Xanthomonas effectors XopQ and XopX results in induction of rice immune responses

Deb, S.; Ghosh, P.; Patel, H. K.; Sonti, R. V.

10.1101/2020.02.07.938365 — molecular biology — Posted on 2020-02-07

2879 Measurement of the torque in braided DNAs using a thermodynamic Maxwell relation

Xiao, B.; Brahmachari, S.; Liu, Y.; Ding, K.; Marko, J. F.

10.1101/2020.02.07.938209 — biophysics — Posted on 2020-02-07

2880 Consensus mutagenesis and ancestral reconstruction provide insight into the substrate specificity and evolution of the front-end Δ6-desaturase family

Li, D.; Damry, A. M.; Petrie, J. R.; Vanhercke, T.; Singh, S. P.; Jackson, C. J.

10.1101/2020.02.07.938332 — biochemistry — Posted on 2020-02-07

2881 Duplications drive diversity in Bordetella pertussis on an underestimated scale.

Abrahams, J. S.; Weigand, M. R.; Ring, N. A.; MacArthur, I.; Peng, S.; Williams, M. M.; Bready, B.; Catalano, A. P.; Davis, J. R.; Kaiser, M. D.; Oliver, J.; Sage, J. M.; Bagby, S.; Tondella, M. L.; Gorringe, A. R.; Preston, A.

10.1101/2020.02.06.937284 — microbiology — Posted on 2020-02-07

2882 Method for in vivo assessment of cancer tissue inhomogeneity and accurate histology-like morphological segmentation based on Optical Coherence Elastography

Plekhanov, A. A.; Sirotkina, M. A.; Sovetsky, A. A.; Gubarkova, E. V.; Kuznetsov, S. S.; Matveyev, A. L.; Matveev, L. A.; Zagaynova, E. V.; Gladkova, N. D.; Zaitsev, V. Y.

10.1101/2020.02.06.937417 — bioengineering — Posted on 2020-02-07

2883 Visual mental imagery engages the left fusiform gyrus, but not the early visual cortex: a meta-analysis of neuroimaging evidence

Spagna, A.; Hajhajate, D.; Liu, J.; Bartolomeo, P.

10.1101/2020.02.06.937151 — neuroscience — Posted on 2020-02-07

2884 Spatial proximity of homologous centromere DNA sequences facilitated karyotype diversity and seeding of evolutionary new centromeres

Guin, K.; Chen, Y.; Mishra, R.; Muzaki, S. R. B. M.; Thimmappa, B. C.; O'Brien, C. E.; Butler, G.; Sanyal, A.; Sanyal, K.

10.1101/2020.02.07.938175 — genetics — Posted on 2020-02-07

2885 Climate explains geographic and temporal variation in mosquito-borne disease dynamics on two continents

Caldwell, J. M.; LaBeaud, A. D.; Lambin, E. F.; Stewart-Ibarra, A. M.; Ndenga, B. A.; Mutuku, F. M.; Krystosik, A. R.; Ayala, E. B.; Anyamba, A.; Borbor-Cordova, M. J.; Damoah, R.; Grossi-Soyster, E. N.; Heras Heras, F.; Ngugi, H. N.; Ryan, S. J.; Shah, M. M.; Sippy, R.; Mordecai, E. A.

10.1101/2020.02.07.938720 — ecology — Posted on 2020-02-07

2886 A framework for implementing metaheuristic algorithms using intercellular communication

Gutierrez, M. E.; Ortiz, Y. M.; Carrion, J.

10.1101/2020.02.06.937979 — synthetic biology — Posted on 2020-02-07

2887 EXO70D isoforms mediate selective autophagic degradation of Type-A ARR proteins to regulate cytokinin sensitivity

Acheampong, A. K.; Shanks, C. M.; Chang, C.-Y.; Schaller, G. E.; Dagdas, Y.; Kieber, J. J.

10.1101/2020.02.07.938712 — plant biology — Posted on 2020-02-07

2888 Development of a Murine Model of Pyogenic Flexor Tenosynovitis

Qiu, B.; Cobb, J.; Loiselle, A. E.; Ketonis, C.

10.1101/2020.02.07.925339 — pathology — Posted on 2020-02-07

2889 The first fossil skull of an anteater (Vermilingua, Myrmecophagidae) from northern South America, a taxonomic reassessment of Neotamandua and a discussion of the myrmecophagid diversification

Jimenez-Lara, K.; Gonzalez, J.

10.1101/793307 — paleontology — Posted on 2020-02-07

2890 Losing Control: Sleep Deprivation Impairs the Suppression of Unwanted Thoughts

Harrington, M. O.; Ashton, J. E.; Sankarasubramanian, S.; Anderson, M. C.; Cairney, S. A.

10.1101/813121 — neuroscience — Posted on 2020-02-07

2891 External error attribution dampens efferent-basedpredictions but not proprioceptive changes in handlocalization

Gastrock, R. Q.; Modchalingam, S.; 't Hart, B. M.; Henriques, D. Y. P.

10.1101/2020.02.05.936062 — neuroscience — Posted on 2020-02-07

2892 Deep predictive coding accounts for emergence of complex neural response properties along the visual cortical hierarchy

Dora, S.; Bohte, S. M.; Pennartz, C. M.

10.1101/2020.02.07.937292 — neuroscience — Posted on 2020-02-07

2893 A Multicenter Preclinical MRI Study: Definition of Rat Brain Relaxometry Reference Maps

Deruelle, T.; Kober, F.; Perles-Barbacaru, A.; Delzescaux, T.; Noblet, V.; Barbier, E. L.; Dojat, M.

10.1101/2020.02.06.928549 — neuroscience — Posted on 2020-02-07

2894 Rational arbitration between statistics and rules in human sequence learning

Maheu, M.; Meyniel, F.; Dehaene, S.

10.1101/2020.02.06.937706 — neuroscience — Posted on 2020-02-07

2895 Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization

Dominguez-Meijide, A.; Vasili, E.; Koenig, A.; Cima-Omori, M.-S.; Leonov, A.; Ryazanov, S.; Zweckstetter, M.; Griesinger, C.; Outeiro, T. F.

10.1101/2020.01.27.921643 — neuroscience — Posted on 2020-02-07

2896 Midbrain modulation of conditioned learning

Tan, K. R.; Rizzi, G.; Li, Z.; Hogrefe, N.

10.1101/2020.02.07.936963 — neuroscience — Posted on 2020-02-07

2897 Low-cost and versatile electrodes for extracellular chronic recordings in rodents

Franca, A. S. C.; van Hulten, J. A.; Cohen, M. S. C.

10.1101/2020.02.06.937201 — neuroscience — Posted on 2020-02-07

2898 Hippocampal and parahippocampal grey matter structural integrity assessed by multimodal imaging is associated with episodic memory in old age

Koehncke, Y.; Duezel, S.; Sander, M. C.; Lindenberger, U.; Kuehn, S.; Brandmaier, A. M.

10.1101/2020.02.07.936872 — neuroscience — Posted on 2020-02-07

2899 Cardiac Microlesions Form During Severe Bacteremic Enterococcus faecalis Infection

Brown, A. O.; Singh, K. V.; Cruz, M. R.; Kaval, K. G.; Francisco, L. E.; Murray, B. E.; Garsin, D. A.

10.1101/2020.01.14.906669 — microbiology — Posted on 2020-02-07

2900 BOSS-RUNS: a flexible and practical dynamic read sampling framework for nanopore sequencing

De Maio, N.; Manser, C.; Munro, R.; Birney, E.; Loose, M. W.; Goldman, N. W.

10.1101/2020.02.07.938670 — genomics — Posted on 2020-02-07

2901 The ancestral C. elegans cuticle suppresses rol-1

Noble, L. M.; Miah, A. M.; Kaur, T.; Rockman, M.

10.1101/2020.02.07.938696 — genetics — Posted on 2020-02-07

2902 A Novel Multiplex qPCR Assay for Detection of Plasmodium falciparum with Histidine-rich Protein 2 and 3 (pfhrp2 and pfhrp3) Deletions in Polyclonal Infections

Grignard, L.; Nolder, D.; Sepulveda, N.; van Schalkwyk, D. A.; Berhane, A.; Mihreteab, S.; Kayaa, R.; Phelan, J.; Moser, K.; Campino, S.; Parr, J.; Juliano, J. J.; Chiodini, P.; Cunningham, J.; Sutherland, C. J.; Drakeley, C.; Beshir, K. B.

10.1101/2020.01.31.928986 — genetics — Posted on 2020-02-07

2903 Physical parameters characterizing dysfunction of neuronal cargo transport caused by the dynein inhibitor ciliobrevin

Hayashi, K.; Miyamoto, M. G.; Niwa, S.

10.1101/2020.02.07.934687 — biophysics — Posted on 2020-02-07

2904 STRIDER: Steric hindrance estimator

Patro, L. P. P.; Rathinavelan, T.

10.1101/2020.02.07.931550 — bioinformatics — Posted on 2020-02-07

2905 coil: an R package for cytochrome C oxidase I (COI) DNA barcode data cleaning, translation, and error evaluation.

Nugent, C. M.; Elliott, T. A.; Ratnasingham, S.; Adamowicz, S. J.

10.1101/2019.12.12.865014 — bioinformatics — Posted on 2020-02-07

2906 Insecticide-free trapping bed-net can mitigate insecticide resistance threat in malaria vector control strategies

Mouhamadou, C.; Luan, K.; Fodjo, B. K.; West, A.; McCord, M.; Apperson, C.; Roe, M.

10.1101/2020.02.06.937623 — bioengineering — Posted on 2020-02-07

2907 Sexual-dimorphism in human immune system aging

Marquez, E. J.; Chung, C.-h.; Marches, R.; Rossi, R. J.; Nehar-Belaid, D.; Mellert, D. J.; Kuchel, G. A.; Banchereau, J.; Ucar, D.

10.1101/755702 — immunology — Posted on 2020-02-07

2908 Spatial distribution and hotspots of mammals in Canada

Cameron, V.; Hargreaves, A. L.

10.1101/2020.01.29.925461 — ecology — Posted on 2020-02-07

2909 Mapping of the nucleolar proteome reveals spatiotemporal organization related to intrinsic protein disorder

Stenstrom, L.; Mahdessian, D.; Gnann, C.; Leonetti, M.; Uhlen, M.; Cuylen-Haering, S.; Thul, P.; Lundberg, E.

10.1101/2020.01.30.923003 — cell biology — Posted on 2020-02-07

2910 A Wnt-BMP4 signalling axis induces MSX and NOTCH proteins and promotes growth suppression and differentiation in neuroblastoma

Szemes, M.; Melegh, Z.; Bellamy, J.; Kollareddy, M.; Catchpoole, D.; Malik, K.

10.1101/2020.02.07.938654 — cancer biology — Posted on 2020-02-07

2911 Transcranial Photobiomodulation with Near-Infrared Light from Childhood to Elderliness: Simulation of Dosimetry

Yuan, Y.; Cassano, P.; Pias, M.; Fang, Q.

10.1101/2020.02.06.937821 — biophysics — Posted on 2020-02-07

2912 Directed assembly and concentrating of micro/nanoparticles, cells, and vesicles via low-power near-infrared laser generated plasmonic microbubbles

Ohannesian, N.; Li, J.; Misbah, I.; Zhao, F.; Shih, W.-C.

10.1101/2020.01.30.927269 — bioengineering — Posted on 2020-02-07

2913 Abstract sequential task control is facilitated by practice and embedded motor sequences

Trach, J. E.; McKim, T. H.; Desrochers, T. M.

10.1101/2020.02.06.937938 — neuroscience — Posted on 2020-02-07

2914 The nucleus accumbens core is necessary to scale fear to degree of threat

Ray, M. H.; Russ, A. N.; Walker, R. A.; McDannald, M. A.

10.1101/2020.02.06.917328 — neuroscience — Posted on 2020-02-07

2915 Distinct neural variables underlie subjective reports of attention

Whitmarsh, S.; Gitton, C.; Jousmäki, V.; Sackur, J.; Tallon-Baudry, C.

10.1101/2020.01.23.916841 — neuroscience — Posted on 2020-02-07

2916 Polyamine Metabolism Regulates the T Cell Epigenome Through Hypusination

Puleston, D. J.; Baixauli, F.; Sanin, D. E.; Villa, M.; Kabat, A.; Kaminski, M. M.; Weiss, H.; Grzes, K.; Flachsmann, L. J.; Field, C. S.; Stanckzak, M.; Schimmelpfennig, L.; Hassler, F.; Wang, C.; Yosef, N.; Kuchroo, V. K.; Musa, Y.; Mittler, G.; Buescher, J. M.; Balabanov, S.; Pearce, E. J.; Green, D. R.; Pearce, E. L.

10.1101/2020.01.24.918094 — immunology — Posted on 2020-02-07

2917 Loss of Sister Kinetochore Co-orientation and Peri-centromeric Cohesin Protection after Meiosis I Depends on Cleavage of Centromeric REC8

Ogushi, S.; Rattani, A.; Godwin, J.; Metson, J.; Schermelleh, L.; Nasmyth, K.

10.1101/2020.02.06.935171 — cell biology — Posted on 2020-02-07

2918 Pathway-guided deep neural network toward interpretable and predictive modeling of drug sensitivity

Liu, H.; Deng, L.; Cai, Y.; Zhang, W.; Yang, W.; Gao, B.

10.1101/2020.02.06.930503 — bioinformatics — Posted on 2020-02-07

2919 DNA Content and Ploidy Estimation of Festuca ovina Accessions by Flow Cytometry

Qiu, Y.; Hamernick, S.; Ortiz, J. B.; Watkins, E.

10.1101/2020.02.06.938100 — plant biology — Posted on 2020-02-07

2920 Association between ocular biometrical parameters and diabetic retinopathy in Chinese adults with type 2 diabetes mellitus

Wang, L.; Liu, S.; Wang, W.; He, M.; Mo, Z.; Gong, X.; Xiong, K.; Li, Y.; Huang, W.

10.1101/2020.02.06.937144 — pathology — Posted on 2020-02-07

2921 The effect of healthy aging on change detection and sensitivity to predictable sturcture in crowded acoustic scenes

de Kerangal, M.; Vickers, D.; Chait, M.

10.1101/2020.02.05.935817 — neuroscience — Posted on 2020-02-07

2922 Comparing Community Detection Methods in Brain Functional Connectivity Networks

Vangimalla, R. R.; Nair, J. S.

10.1101/2020.02.06.935783 — neuroscience — Posted on 2020-02-07

2923 Ratiometric quorum sensing in Enterococcus faecalis conjugation

Banderas, A.; Carcano, A.; Sia, E.; Li, S.; Lindner, A. B.

10.1101/2019.12.11.871699 — microbiology — Posted on 2020-02-07

2924 Incorporating phylogenetic information in microbiome abundance studies has no effect on detection power and FDR control

Bichat, A.; Ambroise, C.; Plassais, J.; Mariadassou, M.

10.1101/2020.01.31.928309 — microbiology — Posted on 2020-02-07

2925 Variation in recombination rate affects detection of FST outliers under neutrality

Booker, T. R.; Yeaman, S.; Whitlock, M.

10.1101/2020.02.06.937813 — evolutionary biology — Posted on 2020-02-07

2926 How important is CRISPR-Cas for protecting natural populations of bacteria against infections with badass DNAs?

Westra, E.; Levin, B. R.

10.1101/2020.02.05.935965 — evolutionary biology — Posted on 2020-02-07

2927 PICH translocase activity is required for proper distribution of SUMOylated proteins on mitotic chromosomes

Hassebroek, V. A.; Park, H.; Pandey, N.; Lerbakken, B.; Aksenova, V.; Arnaoutov, A.; Dasso, M.; Azuma, Y.

10.1101/2020.02.06.937243 — cell biology — Posted on 2020-02-07

2928 Blocking IRE1a-endoribonuclease activity in hepatic stellate cells decreases tumor cell proliferation and metastasis in hepatocellular carcinoma

Pavlovic, N.; Calitz, C.; Thanapirom, K.; Mazza, G.; Rombouts, K.; Gerwins, P.; Heindryckx, F.

10.1101/826453 — cancer biology — Posted on 2020-02-07

2929 Super-resolved polarisation-enhanced second harmonic generation for direct imaging of nanoscale changes in collagen architecture

Johnson, P. B.; Karvounis, A.; Singh, J.; Brereton, C. J.; Bourdakos, K.; Lunn, K.; Roberts, J. J.; Davies, D. E.; Muskens, O. L.; Jones, M. G.; Mahajan, S.

10.1101/2020.02.07.934000 — biophysics — Posted on 2020-02-07

2930 Unbalanced Sample Size Introduces Spurious Correlations to Genome-wide Heterozygosity Analyses

Liu, L.; Caselli, R. J.

10.1101/2020.02.06.937599 — bioinformatics — Posted on 2020-02-07

2931 The Druggable Genome as Seen from the Protein Data Bank

Wang, J.; Yazdani, S.; Han, A.; Schapira, M.

10.1101/2020.02.06.937730 — bioinformatics — Posted on 2020-02-07

2932 Discriminating between sleep and exercise-induced fatigue using computer vision and behavioral genetics

Schuch, K. N.; Govindarajan, L. N.; Guo, Y.; Baskoylu, S. N.; Kim, S.; Kimia, B.; Serre, T.; Hart, A. C.

10.1101/2020.02.06.937359 — animal behavior and cognition — Posted on 2020-02-07

2933 Hippocampal volume in Provisional Tic Disorder predicts tic severity at 12-month follow-up

Kim, S.; Greene, D. J.; Badke D'Andrea, C.; Bihun, E. C.; Koller, J. M.; O'Reilly, B.; Schlaggar, B. L.; Black, K. J.

10.1101/2020.02.05.935908 — neuroscience — Posted on 2020-02-07

2934 Transcriptome analysis of hippocampal subfields identifies gene expression profiles associated with long-term active place avoidance memory

Harris, R. M.; Kao, H.-Y.; Alarcon, J. M.; Fenton, A. A.; Hofmann, H. A.

10.1101/2020.02.05.935759 — neuroscience — Posted on 2020-02-07

2935 Long-term Behavioural Rewriting of Maladaptive Drinking Memories via Reconsolidation-Update Mechanisms

Gale, G.; Hennessy, V. E.; Walsh, K.; Kamboj, S. K.; Das, R. K.

10.1101/2020.02.06.937698 — neuroscience — Posted on 2020-02-07

2936 Assessing performance of pathogenicity predictors using clinically-relevant variant datasets

Gunning, A. C.; Fryer, V.; Fasham, J.; Crosby, A. H.; Ellard, S.; Baple, E.; Wright, C. F.

10.1101/2020.02.06.937169 — genomics — Posted on 2020-02-07

2937 The sudden emergence of a Neisseria gonorrhoeae strain with reduced susceptibility to extended-spectrum cephalosporins, Norway

Osnes, M. N.; Didelot, X.; de Korne-Elenbaas, J.; Alfsnes, K.; Brynildsrud, O. B.; Syversen, G.; Nilsen, O. J.; Caugant, D. A.; de Blasio, B. F.; Eldholm, V.

10.1101/2020.02.07.935825 — genomics — Posted on 2020-02-07

2938 ContamLD: Estimation of Ancient Nuclear DNA Contamination Using Breakdown of Linkage Disequilibrium

Nakatsuka, N. J.; Harney, E.; Mallick, S.; Mah, M.; Patterson, N.; Reich, D. E.

10.1101/2020.02.06.938126 — evolutionary biology — Posted on 2020-02-07

2939 A Small-Bodied Troodontid (Dinosauria, Theropoda) from the Upper Cretaceous Wulansuhai Formation of Inner Mongolia, China

WANG, S.; Tan, Q.; Zhang, Q.; Stiegler, J.; Zhang, H.; Tan, L.

10.1101/2020.02.05.936526 — evolutionary biology — Posted on 2020-02-07

2940 Does Drosophila sechellia escape parasitoid attack by feeding on a toxic resource?

Salazar-Jaramillo, L.; Wertheim, B.

10.1101/2020.02.06.937631 — evolutionary biology — Posted on 2020-02-07

2941 Effects of a postnatal Atrx conditional knockout in neurons on autism-like behaviours in male and female mice

Martin-Kenny, N. A.; Berube, N. G.

10.1101/2020.02.05.936260 — animal behavior and cognition — Posted on 2020-02-07

2942 Cell Fate Clusters in ICM Organoids Arise from Cell Fate Heredity & Division - a Modeling Approach

Liebisch, T.; Drusko, A.; Mathew, B.; Stelzer, E.; Fischer, S. C.; Matthäus, F.

10.1101/698928 — systems biology — Posted on 2020-02-07

2943 Regulatory dynamic enzyme-cost flux balance analysis: A unifying framework for constraint-based modeling

Liu, L.; Bockmayr, A.

10.1101/802249 — systems biology — Posted on 2020-02-07

2944 Unexplained Repeated Pregnancy Loss is Associated with Altered Perceptual and Brain Responses to Men's Body-Odor

Sobel, N.; Rozenkrantz, L.; Weissgross, R.; Weiss, T.; Ravrebi, I.; Frumin, I.; Shushan, S.; Gorodisky, L.; Reshef, N.; Holzman, Y.; Pinchover, L.; Endevelt-Shapi, Y.; Mishor, E.; Furman-Haran, E.; Carp, H.

10.1101/2020.02.06.937029 — physiology — Posted on 2020-02-07

2945 Concurrent MEG-articulography for investigating neuromotor control of speech articulation

Johnson, B. W.; Meng, Q.; Anastasopoulou, I.; Ratko, L.; Szalay, T.; Proctor, M.; Jobst, C.; van Lieshout, P.; Cheyne, D. O.

10.1101/2020.02.05.934489 — neuroscience — Posted on 2020-02-07

2946 Reinforcement regulates timing variability in thalamus

Wang, J.; Hosseini, E.; Meirhaeghe, N.; Akkad, A.; Jazayeri, M.

10.1101/583328 — neuroscience — Posted on 2020-02-07

2947 Structure and meaning organize neural oscillations into a content-specific hierarchy

Kaufeld, G.; Bosker, H. R.; Alday, P. M.; Meyer, A. S.; Martin, A. E.

10.1101/2020.02.05.935676 — neuroscience — Posted on 2020-02-07

2948 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

Cottrell, C. A.; van Schooten, J.; Bowman, C. A.; Yuan, M.; Oyen, D.; Shin, M.; Morpurgo, R.; van der Woude, P.; van Breemen, M.; Torres, J. L.; Patel, R.; Gross, J.; Sewall, L. M.; Copps, J.; Ozorowski, G.; Nogal, B.; Sok, D.; Rakasz, E. G.; Labranche, C.; Vigdorovich, V.; Christley, S.; Carnathan, D. G.; Sather, D. N.; Montefiori, D.; Silvestri, G.; Burton, D.; Moore, J. P.; Wilson, I. A.; Sanders, R. W.; Ward, A. B.; van Gils, M. J.

10.1101/2020.02.05.936096 — immunology — Posted on 2020-02-07

2949 Quantification of the pace of biological aging in humans through a blood test: a DNA methylation algorithm

Belsky, D. W.; Caspi, A.; Arseneault, L.; Corcoran, D. L.; Hannon, E.; Harrington, H. L.; Hartmann-Rasmussen, L. J.; Houts, R.; Huffman, K.; Kraus, W. E.; Mill, J.; Pieper, C.; Prinz, J.; Poulton, R.; Sugden, K.; Williams, B.; Moffitt, T. E.

10.1101/2020.02.05.927434 — genomics — Posted on 2020-02-07

2950 Terrestrial conservation opportunities and inequities revealed by global multi-scale prioritization

Rinnan, D. S.; Jetz, W.

10.1101/2020.02.05.936047 — ecology — Posted on 2020-02-07

2951 EFFECT OF VISUAL CUEING ON TWO-LEGGED HOPPING VARIABILITY IN CHILDREN WITH AUTISM SPECTRUM DISORDER: A PILOT STUDY

Lidstone, D. E.; Dufek, J. S.

10.1101/2020.02.05.936476 — developmental biology — Posted on 2020-02-07

2952 Biocomputational Analysis Establishes Genetic Association of Rheumatoid Arthritis (RA) and Migraine

Roy, N.; Mazumder, A.

10.1101/2020.02.05.936534 — bioinformatics — Posted on 2020-02-07

2953 New observations on non-coding RNAs involved in the dual translation system in zebrafish development.

Breit, T. M.; Pagano, J. F. B.; van der Jagt, P. L.; Mittring, E.; Ensink, W. A.; van Olst, M.; van Leeuwen, S.; de Leeuw, W. C.; Nehrdich, U.; Spaink, H. P.; Rauwerda, H.; Dekker, R. J.

10.1101/869651 — developmental biology — Posted on 2020-02-07

2954 Neural measures of subsequent memory reflect endogenous variability in cognitive function

Weidemann, C. T.; Kahana, M. J.

10.1101/576173 — neuroscience — Posted on 2020-02-07

2955 A shared genetic basis for personality traits and local cortical grey matter structure?

Valk, S. L.; Hoffstaedter, F.; Camilleri, J.; Kochunov, P.; Yeo, B. T. T.; Eickhoff, S. B.

10.1101/645945 — neuroscience — Posted on 2020-02-07

2956 One-time learning in a biologically-inspired Salience-affected Artificial Neural Network (SANN)

Remmelzwaal, L. A.; Ellis, G. F. R.; Tapson, J.

10.1101/726331 — neuroscience — Posted on 2020-02-07

2957 BioID based proteomic analysis of the Bid interactome identifies novel proteins involved in cell cycle dependent apoptotic priming.

Pedley, R.; King, L.; Mallikarjun, V.; Wang, P.; Swift, J.; Brennan, K.; Gilmore, A. P.

10.1101/529685 — cell biology — Posted on 2020-02-07

2958 Adaptive cortical processing of unattended sounds: neurocomputational underpinnings revealed by simultaneous EEG-MEG

Lecaignard, F.; Bertrand, O.; Caclin, A.; Mattout, J.

10.1101/501221 — neuroscience — Posted on 2020-02-07

2959 NSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization

Sasinkova, M.; Herman, P.; Holoubek, A.; Strachotova, D.; Otevrelova, P.; Grebenova, D.; Kuzelova, K.; Brodska, B.

10.1101/2020.02.06.936666 — cell biology — Posted on 2020-02-07

2960 A bacterial size law revealed by a coarse-grained model of cell physiology

Bertaux, F.; Von Kügelgen, J.; Marguerat, S.; Shahrezaei, V.

10.1101/078998 — biophysics — Posted on 2020-02-07

2961 A VTA GABAergic computational model of dissociated reward prediction error computation in classical conditioning

Kaushik, P.; Naude, J.; Raju, S. B.; Alexandre, F.

10.1101/2020.02.06.936997 — neuroscience — Posted on 2020-02-07

2962 Anacardic acid protects against phenylephrine-induced mouse cardiac hypertrophy through JNK signaling-dependent regulation of histone acetylation

Peng, B.; Peng, C.; Luo, X.; Huang, L.; Mao, Q.; Zhang, H.; Han, X.

10.1101/2020.02.06.937672 — cell biology — Posted on 2020-02-07

2963 Two antagonistic microtubule targeting drugs act synergistically to kill cancer cells

Peronne, L.; Denarier, E.; Rai, A.; Prudent, R.; Vernet, A.; Suzanne, P.; Ramirez-Rios, S.; Michallet, S.; Guidetti, M.; Vollaire, J.; Lucena-Agell, D.; Ribba, A.-S.; Josserand, V.; Coll, J.-L.; Dallemagne, P.; Diaz, F.; Oliva, M. A.; Sadoul, K.; Akhmanova, A.; Andrieux, A.; Lafanechere, L.

10.1101/2020.02.06.936849 — cancer biology — Posted on 2020-02-07

2964 Providing an additional electron sink by the introduction of cyanobacterial flavodiirons enhances the growth of Arabidopsis thaliana in varying light

Tula, S.; Shahinnia, F.; Melzer, M.; Rutten, T.; von Wiren, N.; Gomez, R.; Lodeyro, A. F.; Carrillo, N.; Hajirezaei, M.-R.

10.1101/2020.02.05.935346 — biochemistry — Posted on 2020-02-07

2965 The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death

Nuckolls, N. L.; Mok, A. C.; Lange, J. J.; Yi, K.; Kandola, T. S.; Hunn, A. M.; McCroskey, S.; Snyder, J. L.; Bravo Nunez, M. A.; McClain, M.; McKinney, S. A.; Wood, C.; Halfmann, R.; Zanders, S. E.

10.1101/2020.02.05.935874 — cell biology — Posted on 2020-02-07

2966 Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells

Dolan, P. T.; Taguwa, S.; Aguilar Rangel, M.; Acevedo, A.; Andino, R.; Frydman, J.

10.1101/2020.02.05.936195 — microbiology — Posted on 2020-02-07

2967 Genome sequence analysis of a giant-rooted 'Sakurajima daikon' radish (Raphanus sativus)

Shirasawa, K.; Hirakawa, H.; Fukino, N.; Kitashiba, H.; Isobe, S.

10.1101/2020.02.05.936419 — genomics — Posted on 2020-02-07

2968 Comparative transcriptomics across nematode life cycles reveal gene expression conservation and correlated evolution in adjacent developmental stages

Lu, M. R.; Lai, C.-K.; Liao, B.-Y.; Tsai, I. J.

10.1101/2020.02.07.938399 — evolutionary biology — Posted on 2020-02-07

2969 Determinants for forming a supramolecular myelin-like proteolipid lattice

Ruskamo, S.; Krokengen, O. C.; Kowal, J.; Nieminen, T.; Lehtimaki, M.; Raasakka, A.; Dandey, V. P.; Vattulainen, I.; Stahlberg, H.; Kursula, P.

10.1101/2020.02.06.937177 — biochemistry — Posted on 2020-02-07

2970 Pro-inflammatory cytokines drive deregulation of potassium channel expression in primary synovial fibroblasts

Haidar, O.; O'Neill, N.; Staunton, C. A.; Bavan, S.; O'Brien, F.; Zouggari, S.; Sharif, U.; Mobasheri, A.; Kumagai, K.; Barrett-Jolley, R.

10.1101/2020.02.06.937078 — bioinformatics — Posted on 2020-02-07

2971 Regulation of antimycin biosynthesis is controlled by the ClpXP protease

Bilyk, B.; Kim, S.; Fazal, A.; Baker, T. A.; Seipke, R. F.

10.1101/576462 — microbiology — Posted on 2020-02-07

2972 Kinetics of Plasmodium midgut invasion in Anopheles mosquitoes

Volohonsky, G.; Paul-Gilloteaux, P.; Stavkova, J.; Soichot, J.; Salamero, J.; Levashina, E. A.

10.1101/2020.02.06.937276 — immunology — Posted on 2020-02-07

2973 Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts ultimate limit of human lifespan

Pyrkov, T. V.; Avchaciov, K.; Tarkhov, A. E.; Menshikov, L. I.; Gudkov, A. V.; Fedichev, P. O.

10.1101/618876 — systems biology — Posted on 2020-02-07

2974 Bcl6 Preserves the Suppressive Function of Regulatory T Cells during Tumorigenesis

Li, Y.; Wang, Z.; Lin, H.; Wang, L.; Chen, X.; Liu, Q.; Zuo, Q.; Hu, J.; Wang, H.; Guo, J.; Xie, L.; Tang, J.; Li, Z.; Hu, L.; Ye, L.; Huang, Q.; Xu, L.

10.1101/2020.01.21.914812 — immunology — Posted on 2020-02-07

2975 The crustacean Armadillidium vulgare (Latreille, 1804) (Isopoda: Oniscoidea), a new promising model for the study of cellular senescence

Depeux, C.; Samba-Louaka, A.; Becking, T.; Braquart-Varnier, C.; Moreau, J.; Lemaitre, J.-F.; Laverre, T.; Paulhac, H.; Dechaume-Montcharmont, F.-X.; Gaillard, J.-M.; Beltran-Bech, S.

10.1101/583914 — evolutionary biology — Posted on 2020-02-07

2976 Comparison of visualisation tools for single-cell RNAseq data

Cakir, B.; Prete, M.; Huang, N.; van Dongen, S.; Pir, P.; Kiselev, V. Y.

10.1101/2020.01.24.918342 — bioinformatics — Posted on 2020-02-07

2977 Colonization and extinction dynamics match the distribution of European trees at continental scale

Guyennon, A.; Reineking, B.; Dahlgren, J.; Lehtonen, A.; Ratcliffe, S.; Ruiz-Benito, P.; Zavala, M. A.; Kunstler, G.

10.1101/748483 — ecology — Posted on 2020-02-07

2978 PhISCS-BnB: A Fast Branch and Bound Algorithm for the Perfect Tumor Phylogeny Reconstruction Problem

Sadeqi Azer, E.; Rashidi Mehrabadi, F.; Li, X. C.; Malikic, S.; Schaffer, A. A.; Gertz, E. M.; Day, C.-P.; Perez-Guijarro, E.; Marie, K.; Lee, M. P.; Merlino, G.; Ergun, F.; Sahinalp, S. C.

10.1101/2020.02.06.938043 — bioinformatics — Posted on 2020-02-07

2979 An integrated model system to gain mechanistic insights into biofilm formation and antimicrobial resistance development in Pseudomonas aeruginosa MPAO1

Varadarajan, A. R.; Allan, R. N.; Valentin, J. D. P.; Castaneda Ocampo, O. E.; Somerville, V.; Pietsch, F.; Buhmann, M. T.; West, J. J.; Skipp, P. J.; van der Mei, H. C.; Ren, Q.; Schreiber, F.; Webb, J. S.; Ahrens, C. H.

10.1101/2020.02.06.936690 — systems biology — Posted on 2020-02-07

2980 Sex-specific crossover rates did not change with parental age in Arabidopsis

Baskar, R.; Saini, R.; Singh, A. K.; Hyde, G. J.

10.1101/2020.02.06.938183 — plant biology — Posted on 2020-02-07

2981 Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis

Trivedi, S.; Labuz, D.; Anderson, C. P.; Araujo, C. V.; Blair, A.; Middleton, E.; Tran, A.; Mulvey, M.; Campbell, R.; Hale, J. S.; T. Rondina, M.; Leung, D. T.

10.1101/2020.02.05.935866 — physiology — Posted on 2020-02-07

2982 Myelin water fraction decrease in mild traumatic brain injury

Russell-Schulz, B.; Vavasour, I.; Zhang, J.; MacKay, A. L.; Purcell, V.; Muller, A. M.; Brucar, L.; Torres, I. J.; Panenka, W.; Virji-Babul, N.

10.1101/2020.02.05.934430 — neuroscience — Posted on 2020-02-07

2983 Enterococcus faecalis manganese exporter MntE alleviates manganese toxicity and is required for mouse gastrointestinal colonization

Lam, L. N.; Wong, J. J.; Chong, K. K. L.; Kline, K. A.

10.1101/2020.02.06.936633 — microbiology — Posted on 2020-02-07

2984 Bacteriophage SP01 Gene Product 56 (gp56) Inhibits Bacillus subtilis Cell Division by Interacting with DivIC/FtsL to Prevent Pbp2B/FtsW Recruitment

Bhambhani, A.; Iadicicco, I.; Lee, J.; Ahmed, S.; Belfatto, M.; Held, D.; Marconi, A.; Parks, A.; Stewart, C.; Margolin, W.; Levin, P. A.; Haeusser, D. P.

10.1101/2020.02.06.938217 — microbiology — Posted on 2020-02-07

2985 Freshwater monitoring by nanopore sequencing

Urban, L.; Holzer, A.; Baronas, J. J.; Hall, M.; Braeuninger-Weimer, P.; Scherm, M. J.; Kunz, D. J.; Perera, S. N.; Martin-Herranz, D. E.; Tipper, E. T.; Salter, S. J.; Stammnitz, M. R.

10.1101/2020.02.06.936302 — microbiology — Posted on 2020-02-07

2986 PGC1/PPAR Drive Cardiomyocyte Maturation through Regulation of Yap1 and SF3B2

Murphy, S.; Miyamoto, M.; Kervadec, A.; Kannan, S.; Tampakakis, E.; Kambhampati, S.; Lin, B. L.; Paek, S.; Andersen, P.; Lee, D.-I.; Zhu, R.; An, S. S.; Kass, D. A.; Uosaki, H.; Colas, A. R.; Kwon, C.

10.1101/2020.02.06.937797 — developmental biology — Posted on 2020-02-07

2987 A gatekeeping role of ESR2 to maintain the primordial follicle reserve

Rumi, M. A.; Chakravarthi, V. P.; Ghosh, S.; Roby, K. F.; Wolfe, M. W.

10.1101/2020.02.06.937953 — developmental biology — Posted on 2020-02-07

2988 Targeted biomass degradation by the higher termite gut system - integrative omics applied to host and its gut microbiome

Calusinska, M.; Marynowska, M.; Bertucci, M.; Untereiner, B.; Klimek, D.; Goux, X.; Sillam-Dusses, D.; Gawron, P.; Halder, R.; Wilmes, P.; Ferrer, P.; Gerin, P.; Roisin, Y.; Delfosse, P.

10.1101/2020.02.06.937128 — systems biology — Posted on 2020-02-07

2989 PKMζ traces hippocampal LTP maintenance and spatial long-term memory

Hsieh, C.; Tsokas, P.; Chung, A.; Garcia-Jou, C.; Lesburgueres, E.; Burghardt, N. S.; Denny, C. A.; Flores-Obando, R. E.; Valencia, L. M. R.; Bergold, P.; Cottrell, J. E.; Fenton, A. A.; Sacktor, T. C.

10.1101/2020.02.05.936146 — neuroscience — Posted on 2020-02-07

2990 Aberrant sorting of hippocampal complex pyramidal cells in Type I Lissencephaly alters topological innervation

D'Amour, J. A.; Ekins, T.; Ganatra, S.; Yuan, X.; McBain, C. J.

10.1101/2020.02.05.935775 — neuroscience — Posted on 2020-02-07

2991 Time-restricted feeding from adulthood to old age improves biconditional associative learning in geriatric rats regardless of macronutrient composition

Hernandez, A. R.; Federico, Q. P.; Burke, S. N.

10.1101/2020.02.06.937532 — neuroscience — Posted on 2020-02-07

2992 Cortico-subthalamic projections send brief stop signals to halt visually-guided locomotion

Adam, E. M.; Johns, T.; Sur, M.

10.1101/2020.02.05.936443 — neuroscience — Posted on 2020-02-07

2993 Targeting OCA-B/Pou2af1 blocks type-1 diabetes and reduces infiltration of activated, islet-reactive T cells

Kim, H.; Perovanovic, J.; Shakya, A.; Shen, Z.; German, C. N.; Ibarra, A.; Jafek, J.; Evavold, B. D.; Chou, D. H.- C.; Jensen, P. E.; He, X.; Tantin, D.

10.1101/2020.02.06.937839 — immunology — Posted on 2020-02-07

2994 A genome-wide case-only test for the detection of digenic inheritance in human exomes

Kerner, G.; Bouaziz, M.; Cobat, A.; Bigio, B.; Timberlake, A. T.; Bustamante, J.; Lifton, R. P.; Casanova, J.-L.; Abel, L.

10.1101/2020.02.06.936922 — genetics — Posted on 2020-02-07

2995 Type II Fusarium head blight susceptibility factor identified in wheat

Hales, B.; Steed, A.; Giovannelli, V.; Burt, C.; Lemmens, M.; Molnar-Lang, M.; Nicholson, P.

10.1101/2020.02.06.937425 — genetics — Posted on 2020-02-07

2996 How important is CRISPR-Cas for protecting natural populations of bacteria against infections with badass DNAs?

Westra, E.; Levin, B. R.

10.1101/2020.02.05.935965 — evolutionary biology — Posted on 2020-02-07

2997 Structural adaptation of oxygen tolerance in 4-hydroxybutyrl-CoA dehydratase, a key enzyme of archaeal carbon fixation

DeMirci, H.; Tolar, B.; Doukov, T.; Petriceks, A.; Pal, A.; Yoshikuni, Y.; Saez, D. A.; Murillo-Lopez, J. A.; Rabanal-Leon, W. A.; Vohringer-Martinez, E.; Schwander, T.; Erb, T. J.; Francis, C. A.; Wakatsuki, S.

10.1101/2020.02.05.935528 — evolutionary biology — Posted on 2020-02-07

2998 Shape matters: cell geometry determines phytoplankton diversity

Ryabov, A.; Kerimoglu, O.; Litchman, E.; Olenina, I.; Roselli, L.; Basset, A.; Stanca, E.; Blasius, B.

10.1101/2020.02.06.937219 — ecology — Posted on 2020-02-07

2999 Cellular heterogeneity of the LH receptor and its significance for cyclic GMP signaling in mouse preovulatory follicles

Baena, V.; Owen, C. M.; Yee, S.-P.; Terasaki, M.; Egbert, J.; Jaffe, L. A.

10.1101/2020.02.06.937995 — cell biology — Posted on 2020-02-07

3000 The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Duran-Ferrer, M.; Clot, G.; Nadeu, F.; Beekman, R.; Bauman, T.; Nordlund, J.; Marincevic-Zuniga, Y.; Lonnerholm, G.; Rivas, A.; Ordonez, R.; Castellano, G.; Kulis, M.; Queiros, A.; Seung-Tae, L.; Gine, E.; Bea, S.; Jares, P.; Agirre, X.; Prosper, F.; Puente, X. S.; Lopez-Otin, C.; Zenz, T.; Oakes, C.; Delgado, J.; Lopez-Guillermo, A.; Campo, E.; Martin-Subero, J. I.

10.1101/2020.02.06.937383 — cancer biology — Posted on 2020-02-07

3001 Multi-organ transcriptomic landscape of Ambystoma velasci metamorphosis

Palacios-Martinez, J.; Caballero-Perez, J.; Espinal-Centeno, A.; Marquez-Chavoya, G.; Lomeli, H.; Salas-Vidal, E.; Schnabel, D.; Chimal-Monroy, J.; Cruz-Ramirez, A.

10.1101/2020.02.06.937896 — developmental biology — Posted on 2020-02-07

3002 Formal model of Parkinson's disease neurons unveils possible causality links in the pathophysiology of the disease

Nadal, M.; Kaminski Schierle, G. S.; Dikicioglu, D.

10.1101/2020.02.06.937664 — systems biology — Posted on 2020-02-07

3003 DNA Content and Ploidy Estimation of Festuca ovina Accessions by Flow Cytometry

Qiu, Y.; Hamernick, S.; Ortiz, J. B.; Watkins, E.

10.1101/2020.02.06.938100 — plant biology — Posted on 2020-02-07

3004 Hydrogen sulfide exposure reduces thermal set point in zebrafish

Skandalis, D. A.; Dobell, C. D.; Shaw, J. C.; Tattersall, G. J.

10.1101/2020.02.06.935957 — physiology — Posted on 2020-02-07

3005 Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells

Rivers, E.; Rai, R.; Lotscher, J.; Hollinshead, M.; Markelj, G.; Thaventheran, J.; Worth, A.; Cavazza, A.; Hess, C.; Bajaj-Elliott, M.; Thrasher, A. J.

10.1101/2020.02.06.937946 — physiology — Posted on 2020-02-07

3006 Non-linear Computation Between Neighboring Dendritic Hotspots in Rat CA1 Hippocampal Interneurons

Kaszas, A.; Szadai, Z.; Spitzer, K.; Katona, G.; Toth, E.; Tamas, G.; Rozsa, B.

10.1101/2020.02.06.936989 — neuroscience — Posted on 2020-02-07

3007 The McGill-Mouse-Marmoset Platform: A Standardized Approach for High-throughput Imaging of Neuronal Dynamics During Behavior

Mosser, C.-A.; Haqqee, Z.; Nieto-Posadas, A.; Murai, K. K.; Stifani, S.; Williams, S.; Brandon, M. P.

10.1101/2020.02.06.937573 — neuroscience — Posted on 2020-02-07

3008 Epstein Barr virus epitope/MHC interaction combined with convergent recombination drive selection of diverse T cell receptor a and b repertoires

Gil, A.; Kamga, L.; Chirravuri-Venkata, R.; Aslan, N.; Clark, F. G.; Ghersi, D.; Luzuriaga, K.; Selin, L. K.

10.1101/2020.02.06.938241 — immunology — Posted on 2020-02-07

3009 Vitamin D regulates MerTK-dependent phagocytosis in human myeloid cells

Clarke, J.; Yaqubi, M.; Futhey, N. C.; Sedaghat, S.; Baufeld, C.; Blain, M.; Baranzini, S.; Butovsky, O.; Antel, J.; White, J. H.; Healy, L. M.

10.1101/2020.02.06.937482 — immunology — Posted on 2020-02-07

3010 A convNet based multi-label microRNA subcellular location predictor, by incorporating k-mer positional encoding

Asim, M. N.; Dengel, A.; Ahmed, S.

10.1101/2020.02.06.937656 — genomics — Posted on 2020-02-07

3011 A framework to quantify phenotypic and genotypic parallel evolution

James, M. E.; Melanie, W. J.; North, H. L.; Engelstaedter, J.; Ortiz-Barrientos, D.

10.1101/2020.02.05.936450 — evolutionary biology — Posted on 2020-02-07

3012 Predatory colponemids are the sister group to all other alveolates

Tikhonenkov, D. V.; Strassert, J. F. H.; Janouskovec, J.; Mylnikov, A. P.; Aleoshin, V. V.; Burki, F.; Keeling, P. J.

10.1101/2020.02.06.936658 — evolutionary biology — Posted on 2020-02-07

3013 Single-cell sequencing of developing human gut reveals transcriptional links to childhood Crohns disease

Elmentaite, R.; Ross, A.; James, K. R.; Ortmann, D.; Gomes, T.; Roberts, K.; Nayak, K.; Tuck, L.; Bayraktar, O.; Heuschkel, R.; Vallier, L.; Teichmann, S. A.; Zilbauer, M.

10.1101/2020.02.06.937110 — cell biology — Posted on 2020-02-07

3014 ProTrack: An Interactive Multi-Omics Data Browser for Proteogenomic Studies

Calinawan, A. P.; Song, X.; Ji, J.; Dhanasekaran, S. M.; Petralia, F.; Wang, P.; Reva, B.

10.1101/2020.02.05.935650 — bioinformatics — Posted on 2020-02-07

3015 Identifying Informative Gene Modules Across Modalities of Single Cell Genomics

DeTomaso, D.; Yosef, N.

10.1101/2020.02.06.937805 — bioinformatics — Posted on 2020-02-07

3016 Structure-function analysis of the maize bulliform cell cuticle and its role in dehydration and leaf rolling

Matschi, S.; Vasquez, M. F.; Bourgault, R.; Steinbach, P.; Chamness, J.; Kaczmar, N.; Gore, M. A.; Molina, I.; Smith, L. G.

10.1101/2020.02.06.937011 — plant biology — Posted on 2020-02-07

3017 Recombinant human MG53 protein preserves mitochondria integrity in cardiomyocytes during ischemia reperfusion-induced oxidative stress

Gumpper, K.; Ma, H.; Krishnamurthy, K.; Zhou, X.; Park, K. H.; Sermersheim, M.; Zhou, J.; Tan, T.; Lin, P.-H.; Li, L.; Liu, J.; Zhu, H.; Ma, J.

10.1101/2020.02.06.936278 — physiology — Posted on 2020-02-07

3018 The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse

Berwian, I. M.; Wenzel, J. G.; Kuehn, L.; Schnuerer, I.; Kasper, L.; Veer, I. M.; Seifritz, E.; Stephan, K. E.; Walter, H.; Huys, Q. J. M.

10.1101/2020.02.06.937268 — neuroscience — Posted on 2020-02-07

3019 TaxisPy: A Python-based Software for the Quantitative Analysis of Bacterial Chemotaxis

Valderrama-Gomez, M. A.; Schomer, R. A.; Savageau, M. A.; Parales, R. E.

10.1101/2020.02.06.937714 — microbiology — Posted on 2020-02-07

3020 Ascorbate maintains a low plasma low oxygen level

Injarabian, L.; Scherlinger, M.; Devin, A.; Ransac, S.; Lykkesfeldt, J.; Marteyn, B. S.

10.1101/2020.02.06.937037 — immunology — Posted on 2020-02-07

3021 The multiplicity of infection does not affect interactions between Cryptococcus neoformans and macrophages

Pline, K. M.; Johnston, S.

10.1101/2020.02.05.936427 — immunology — Posted on 2020-02-07

3022 Next generation cytogenetics: comprehensive assessment of 48 leukemia genomes by genome imaging

Neveling, K.; Mantere, T.; Vermeulen, S.; Oorsprong, M.; van Beek, R.; Kater-Baats, E.; Pauper, M.; van der Zande, G.; Smeets, D.; Olde Weghuis, D.; Stevens-Kroef, M.; Hoischen, A.

10.1101/2020.02.06.935742 — genomics — Posted on 2020-02-07

3023 Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development

Maccallini, P.; Bavasso, F.; Scatolini, L.; Bucciarelli, E.; Noviello, G.; Lisi, V.; Palumbo, V.; D'Angeli, S.; Cacchione, S.; Cenci, G.; Ciapponi, L.; Wakefield, J. G.; Gatti, M.; raffa, g. d.

10.1101/2020.02.06.936724 — genetics — Posted on 2020-02-07

3024 Highly replicated evolution of parapatric ecotypes

James, M. E.; Arenas-Castro, H.; Groh, J. S.; Engelstaedter, J.; Ortiz-Barrientos, D.

10.1101/2020.02.05.936401 — evolutionary biology — Posted on 2020-02-07

Wong, M. K. L.; Tsang, T. P. N.; Lewis, O. T.; Guenard, B.

10.1101/2020.02.05.935858 — ecology — Posted on 2020-02-07

3026 The TIM22 complex regulates mitochondrial one-carbon metabolism by mediating the import of Sideroflexins

Stojanovski, D.; Jackson, T. D.; Hock, D.; Palmer, C.; Kang, Y.; Fujihara, K.; Clemons, N.; Thorburn, D.; Stroud, D. A.

10.1101/2020.02.06.937920 — cell biology — Posted on 2020-02-07

3027 Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy.

Pikman, Y.; Ocasio-Martinez, N.; Alexe, G.; Kitara, S.; Diehl, F. F.; Robichaud, A. L.; Conway, A.; Su, A.; Qi, J.; Roti, G.; Lewis, C. A.; Puissant, A.; Vander Heiden, M. G.; Stegmaier, K.

10.1101/2020.02.06.936286 — cancer biology — Posted on 2020-02-07

3028 A database resource for Genome-wide dynamics analysis of Coronaviruses on a historical and global scale

Zhu, Z.; Meng, K.; Meng, G.

10.1101/2020.02.05.920009 — bioinformatics — Posted on 2020-02-07

3029 A Pre-computed Probabilistic Molecular Search Engine for Tandem Mass Spectrometry Proteomics

Jones, J.

10.1101/2020.02.06.937870 — bioinformatics — Posted on 2020-02-07

3030 Comparative analysis of CPI-motif regulation of biochemical functions of actin capping protein

McConnell, P.; Mekel, M.; Kozlov, A. G.; Mooren, O. L.; Lohman, T. M.; Cooper, J. A.

10.1101/2020.02.06.936211 — biochemistry — Posted on 2020-02-07

3031 A biodiverse package of southwest Asian grain crops facilitated high-elevation agriculture in the central Tien Shan during the mid-third millennium BCE

Giedre, M. M.; Hermes, T. R.; Mir-Makhamad, B.; Tabaldiev, K.

10.1101/2020.02.06.936765 — plant biology — Posted on 2020-02-06

3032 A Precision Medicine Approach to Stress Testing Using Metabolomics and MicroRibonucleic Acids

Limkakeng, A. T.; Rowlette, L.-L.; Hatch, A.; Nixon, A.; Ilkayeva, O.; Corcoran, D.; Modliszewski, J.; Griffin, S. M.; Ginsberg, G. S.; Voora, D.

10.1101/2020.02.06.936757 — physiology — Posted on 2020-02-06

3033 A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: application to a dose-finding trial for a novel Russell's viper antivenom in Myanmar

Watson, J. A.; Lamb, T.; Holmes, J.; Warrell, D.; Thwin, K. T.; Aung, Z. L.; Nwe, M. T.; Smithuis, F.; Ashley, E. A.

10.1101/2020.02.06.936815 — pharmacology and toxicology — Posted on 2020-02-06

3034 Study of Staphylococcus aureus Biofilm Ability to Destroy Bone Matrix in Absences of Host

Al Ghaithi, a.; Al Mastari, S.; Husband, J.; al kindi, M.; Al Bimani, A.

10.1101/2020.02.06.936799 — cell biology — Posted on 2020-02-06

3035 Multi- Stage Feature Selection (MSFS) Algorithm for UWB- Based Early Breast Cancer Size Prediction

VEERAPERUMAL, V.; ANDREW, A. M.; JUSOH, M.; SABAPATHY, T.; A RAOF, R. A.; MOHD YASIN, M. N.; AHMAD, R. B.; KHATUN, S.

10.1101/2020.02.06.936831 — bioinformatics — Posted on 2020-02-06

3036 Directed effective connectivity and synaptic weights of invitro neuronal cultures revealed from high-density multielectrode array recordings

Sun, C.; Lin, K. C.; Huang, Y.-T.; Ching, E. S. C.; Lai, P.-Y.; Chan, C. K.

10.1101/2020.02.06.936781 — neuroscience — Posted on 2020-02-06

3037 Response of Asplenium nidus to Drought Stress and Identification of Drought Tolerance Genes

Xu, S.; Yu, W.; Liang, J.

10.1101/2020.02.06.936773 — genetics — Posted on 2020-02-06

3038 Population dynamics in pre-Inca human groups from the Osmore Valley, the Azapa Valley and the coast of the south central Andes

Coppa, A.; Candilio, F.; Arganini, C.; de la Vega, E.; Moreno Terrazas, E. G.; Lucci, M.; Cucina, A.

10.1101/2020.02.06.936823 — evolutionary biology — Posted on 2020-02-06

3039 Brucella species circulating in wildlife in Serengeti ecosystem, Tanzania

Sambu, R. M.; Mathew, C.; Nonga, H. E.; Lukambagire, A. S.; Yapi, R. B.; Fokou, G.; Keyyu, J.; Bonfoh, B.; Kazwala, R. R.

10.1101/2020.02.06.936807 — microbiology — Posted on 2020-02-06

3040 Combining multiple functional connectivity methods to improve causal inferences

Sanchez-Romero, R.; Cole, M. W.

10.1101/841890 — neuroscience — Posted on 2020-02-06

3041 Dynamic macromolecular composition and high exudation rates in Prochlorococcus

Roth-Rosenberg, D.; Aharonovich, D.; Omta, A.-W.; Follows, M. J.; Sher, D. J.

10.1101/828897 — microbiology — Posted on 2020-02-06

3042 Leveraging functional annotation to identify genes associated with complex diseases

Liu, W.; Li, M.; Zhang, W.; Zhou, G.; Wu, X.; Wang, J.; Zhao, H.

10.1101/529297 — genetics — Posted on 2020-02-06

3043 Low-disturbance farming regenerates healthy critical zone towards sustainable agriculture

Deng, F.; Wang, H.; Xie, H.; Bao, X.; He, H.; Zhang, X.; Liang, C.

10.1101/828673 — ecology — Posted on 2020-02-06

3044 Yeast Chd1p remodels nucleosomes with unique DNA unwrapping and translocation dynamics

Kirk, J.; Lee, J. Y.; Lee, Y.; Kang, C.; Shin, S.; Lee, E.; Song, J.-J.; Hohng, S.

10.1101/376806 — biophysics — Posted on 2020-02-06

3045 Efficiency of biological and chemical inducers for controlling Septoria tritici leaf blotch (STB) on wheat (Triticum aestivum L.)

BELLAMECHE, F.; Pedrazzini, C.; Mauch-Mani, B.; Mascher, F.

10.1101/2020.02.06.936583 — plant biology — Posted on 2020-02-06

3046 The tapejarid pterosaur Tupandactylus imperator from Crato Formation and the preservation of cranial integuments

Nascimento Campos, H. B.; Kischlat, E.-E.

10.1101/2020.02.06.937458 — paleontology — Posted on 2020-02-06

3047 Hedgehog Signalling Modulates Glial Proteostasis and Lifespan.

Rallis, A.; Navarro, J.; Rass, M.; Hu, A.; Birman, S.; Schneuwly, S.; Therond, P.

10.1101/2020.02.05.935585 — neuroscience — Posted on 2020-02-06

3048 Translational control of methionine and serine metabolic pathways underpin the paralog-specific phenotypes of Rpl22 ribosomal protein mutants in cell division and replicative longevity

Maitra, N.; He, C.; Blank, H. M.; Tsuchiya, M.; Schilling, B.; Kaeberlein, M.; Aramayo, R.; Kennedy, B. K.; Polymenis, M.

10.1101/2020.02.05.935726 — molecular biology — Posted on 2020-02-06

3049 Bud23 promotes the progression of the Small Subunit Processome to the pre-40S ribosome in Saccharomyces cerevisiae

Black, J. J.; Sardana, R.; Elmir, E. W.; Johnson, A.

10.1101/2020.02.05.936237 — molecular biology — Posted on 2020-02-06

3050 MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis

Sangokoya, C.; Blelloch, R.

10.1101/2020.02.06.936070 — developmental biology — Posted on 2020-02-06

3051 Loss of Sister Kinetochore Co-orientation and Peri-centromeric Cohesin Protection after Meiosis I Depends on Cleavage of Centromeric REC8

Ogushi, S.; Rattani, A.; Godwin, J.; Metson, J.; Schermelleh, L.; Nasmyth, K.

10.1101/2020.02.06.935171 — cell biology — Posted on 2020-02-06

3052 Functional in vivo characterization of zebrafish sox10 enhancers in melanoma and neural crest

Cunningham, R. L.; Kramer, E. T.; DeGeorgia, S. K.; Seneviratne, S.; Grigura, V.; Kaufman, C. K.

10.1101/2020.02.06.932178 — cancer biology — Posted on 2020-02-06

3053 Large-scale in silico mutagenesis experiments reveal optimization of genetic code and codon usage for protein mutational robustness

Schwersensky, M.; Rooman, M.; Pucci, F.

10.1101/2020.02.05.935809 — bioinformatics — Posted on 2020-02-06

3054 Conserved small nucleotidic elements at the origin of concerted piRNA biogenesis from genes and lncRNAs

Jensen, S.; Brasset, E.; Parey, E.; Roest Crollius, H.; Sharakhov, I. V.; Vaury, C.

10.1101/2020.02.05.936112 — bioinformatics — Posted on 2020-02-06

3055 A robust mean and variance test with application to epigenome-wide association studies

Staley, J. R.; Windmeijer, F.; Suderman, M.; Davey Smith, G.; Tilling, K.

10.1101/2020.02.06.926584 — bioinformatics — Posted on 2020-02-06

3056 mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding

Bao, C.; Loerch, S.; Ling, C.; Korostelev, A. A.; Grigorieff, N.; Ermolenko, D.

10.1101/2020.02.05.936120 — biochemistry — Posted on 2020-02-06

3057 Histopathological aspects of induced resistance by Pseudomonas protegens CHA0 and β-aminobutyric acid in wheat against Puccinia triticina

BELLAMECHE, F.; Jasim, M. A.; Mauch-Mani, B.; Mascher, F.

10.1101/2020.02.06.934943 — plant biology — Posted on 2020-02-06

3058 The Arabidopsis gene RGO mediates cytokinin responses and increases seed yield

Murmu, J.; Allard, G.; Chabot, D.; Nambara, E.; Datla, R.; Hepworth, S. R.; Subramanian, R.; Singh, J.

10.1101/2020.02.06.937342 — plant biology — Posted on 2020-02-06

3059 The Endothelial Protein C Receptor plays an essential role in the maintenance of Pregnancy

Castillo, M. M.; Yang, Q.; Solis Sigala, A.; McKinney, D. T.; Zhan, M.; Chen, K. L.; Jarzembowski, J. A.; Sood, R.

10.1101/2020.02.05.935940 — physiology — Posted on 2020-02-06

3060 Optimal Binning of Peri-Event Time Histograms Using Akaike Information Criterion

Ghazizadeh, A.; Ambroggi, F.

10.1101/2020.02.06.937367 — neuroscience — Posted on 2020-02-06

3061 Escherichia coli σ38 promoters use two UP elements instead of a -35 element: resolution of a paradoxand discovery that σ38 transcribes ribosomal promoters

Franco, K. S.; Sun, Z.; Chen, Y.; Cagliero, C.; Zuo, Y.; Zhou, Y. N.; Kashlev, M.; Jin, D.; Schneider, T. D.

10.1101/2020.02.05.936344 — molecular biology — Posted on 2020-02-06

3062 Rapid and real-time identification of fungi up to the species level with long amplicon Nanopore sequencing from clinical samples.

D'Andreano, S.; Cusco, A.; Francino, O.

10.1101/2020.02.06.936708 — microbiology — Posted on 2020-02-06

3063 Engineering isoprenoid quinone production in yeast

Kaur, D.; Corre, C.; Alberti, F.

10.1101/2020.02.06.932020 — microbiology — Posted on 2020-02-06

3064 Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency

Krishna, B. A.; Wass, A. B.; O'Connor, C. M.

10.1101/2020.02.06.929281 — microbiology — Posted on 2020-02-06

3065 Large-scale RNAi screening uncovers new therapeutic targets in the human parasite Schistosoma mansoni

Wang, J.; Paz, C.; Padalino, G.; Coghlan, A.; Lu, Z.; Gradinaru, I.; Collins, J. N. R.; Berriman, M.; Hoffman, K. F.; Collins, J.

10.1101/2020.02.05.935833 — microbiology — Posted on 2020-02-06

3066 Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

Lam, M.; Chen, C.-Y.; Yan, X.; Hill, D. W.; Trampush, J.; Yu, J.; Knowles, E.; Davies, G.; Stahl, E.; Huckins, L.; Liewald, D. C.; Djurovic, S.; Melle, I.; Christoforou, A.; Reinvang, I.; DeRosse, P.; Lundervold, A. J.; Steen, V. M.; Espeseth, T.; Raikkonen, K.; Widen, E.; Palotie, A.; Eriksson, J. G.; Giegling, I.; Konte, B.; Hartmann, A. M.; Roussos, P.; Giakoumaki, S.; Burdick, K. E.; Payton, A.; Ollier, W.; Chiba-Falek, O.; Koltai, D. K.; Need, A. C.; Cirulli, E. T.; Voineskos, A. N.; Stefanis, N. C.; Avramopoulos, D.; Hatzimanolis, A.; Smyrnis, N.; Bilder, R. M.; Freimer, N. A.; Cannon, T

10.1101/2020.02.06.934752 — genomics — Posted on 2020-02-06

3067 dyngen: a multi-modal simulator for spearheading new single-cell omics analyses

Cannoodt, R.; Saelens, W.; Deconinck, L.; Saeys, Y.

10.1101/2020.02.06.936971 — bioinformatics — Posted on 2020-02-06

3068 Biotic and abiotic factors predict the biogeography of soil microbes in the Serengeti

Stevens, B. M.; Sonderegger, D.; Johnson, N.

10.1101/2020.02.06.936625 — microbiology — Posted on 2020-02-06

3069 FluoSim: simulator of single molecule dynamics for fluorescence live-cell and super-resolution imaging of membrane proteins

Lagardere, M.; Chamma, I.; Bouilhol, E.; Nikolski, M.; Thoumine, O.

10.1101/2020.02.06.937045 — biophysics — Posted on 2020-02-06

3070 Distinct error rates for reference and non-reference genotypes estimated by pedigree analysis

Wang, R. J.; Radivojac, P.; Hahn, M. W.

10.1101/2020.02.06.937649 — bioinformatics — Posted on 2020-02-06

3071 Evolutionary context can clarify teleosts gene names

Gasanov, E.; Jedrychowska, J.; Kuznicki, J.; Korzh, V.

10.1101/2020.02.02.931493 — genomics — Posted on 2020-02-06

3072 In situ structure determination of virus capsids imaged within cell nuclei by correlative light and cryo-electron tomography.

Vijayakrishnan, S.; McElwee, M.; Loney, C.; Rixon, F. J.; Bhella, D.

10.1101/2020.02.06.936948 — biophysics — Posted on 2020-02-06

3073 Quantitative single-cell interactomes in normal and virus-infected mouse lungs

Cain, M. P.; Hernandez, B. J.; Chen, J.

10.1101/2020.02.05.936054 — bioinformatics — Posted on 2020-02-06

3074 Build me up to break me down: Frothed spawn in the sandpaper frog, Lechriodus fletcheri, is formed by female parents and later broken down by their offspring

Gould, J.

10.1101/2020.02.06.937409 — zoology — Posted on 2020-02-06

3075 Silicon modulates multi-layered defense against powdery mildew in Arabidopsis

Wang, L.; Dong, M.; Zhang, Q.; Wu, Y.; Hu, L.; Parson, J. F.; Eisenstein, E.; Du, X.; Xiao, S.

10.1101/2020.02.05.935734 — plant biology — Posted on 2020-02-06

3076 Memo1 gene expression in kidney and bone is unaffected by dietary mineral load and calciotropic hormones

Moor, M. B.; Bonny, O.

10.1101/2020.02.06.933960 — physiology — Posted on 2020-02-06

3077 Pharmacological inhibition of longevity regulator PAPP-A restrains mesenchymal stromal cell activity

Mohrin, M.; Liu, J.; Zavala-Solorio, J.; Bhargava, S.; Trumble, J. M.; Brito, A.; Hu, D.; Brooks, D.; Bouxsein, M. L.; Baron, R.; Kutskova, Y.; Freund, A.

10.1101/2020.02.05.936310 — physiology — Posted on 2020-02-06

3078 Instant FLIM enables 4D in vivo lifetime imaging of intact brains

Zhang, Y.; Guldner, I. H.; Nichols, E. L.; Benirschke, D.; Smith, C. J.; Zhang, S.; Howard, S. S.

10.1101/2020.02.05.936039 — neuroscience — Posted on 2020-02-06

3079 Lateralised cerebral processing of abstract linguistic structure in clear and degraded speech

Meng, Q.; Li Hegner, Y.; Giblin, I.; McMahon, C.; Johnson, B. W.

10.1101/2020.02.05.934604 — neuroscience — Posted on 2020-02-06

3080 Direct Observation Of Vesicle Transport On The Synaptic Ribbon Provides Evidence That Vesicles Are Mobilized And Prepared Rapidly For Release

Joselevitch, C.; Zenisek, D.

10.1101/2020.02.05.936153 — neuroscience — Posted on 2020-02-06

3081 Exploratory Factor Analysis with Structured Residuals for Brain Imaging Data

van Kesteren, E.-J.; Kievit, R. A.

10.1101/2020.02.06.933689 — neuroscience — Posted on 2020-02-06

3082 Parallel lemniscal and non-lemniscal sources control auditory responses in the orbitofrontal cortex (OFC)

Srivastava, H. K.; Bandyopadhyay, S.

10.1101/2020.02.05.935569 — neuroscience — Posted on 2020-02-06

3083 A versatile vector system for the fast generation of knock-in cell lines with CRISPR

Perez-Leal, O.; Nixon-Abell, J.; Barrero, C. A.; Gordon, J.; Rico, M. C.

10.1101/2020.02.06.927384 — molecular biology — Posted on 2020-02-06

3084 A hierarchical transcriptional network controls appressorium-mediated plant infection by the rice blast fungus Magnaporthe oryzae

Oses-Ruiz, M.; Martin-Urdiroz, M.; Soanes, D. M.; Kershaw, M. J.; Cruz-Mireles, N.; Valdovinos-Ponce, G.; Molinari, C.; Littlejohn, G. R.; Derbyshire, P.; Menke, F.; Valent, B.; Talbot, N. J.

10.1101/2020.02.05.936203 — microbiology — Posted on 2020-02-06

3085 Growth phase-dependent responses of an in vitro gut microbiome to metformin

Hao, Z.; Li, L.; Ning, Z.; Zhang, X.; Mayne, J.; Cheng, K.; Walker, K.; Liu, H.; Figeys, D.

10.1101/2020.02.05.936500 — microbiology — Posted on 2020-02-06

3086 Although host-related factors are important for the formation of gut microbiota, environmental factors cannot be ignored

Jung, Y.; Kerfahi, D.; Pham, H. Q.; Son, H.; Ibal, J. C.; Park, M.-K.; Park, Y.-J.; Park, C. E.; Choi, S.-D.; Jo, Y.; Kim, M.-C.; Kim, M. J.; Kang, G. U.; Jo, H. W.; Yun, H.; Lee, B.; Park, C. Y.; Kim, E. S.; Kim, S.-J.; Shin, J.-H.

10.1101/2020.02.03.933317 — microbiology — Posted on 2020-02-06

3087 Ultrastructural Visualization of 3D Chromatin Folding Using Serial Block-Face Scanning Electron Microscopy and In Situ Hybridization (3D-EMISH)

Trzaskoma, P.; Ruszczycki, B.; Lee, B.; Pels, K. K.; Krawczyk, K.; Bokota, G.; Szczepankiewicz, A. A.; Aaron, J.; Walczak, A.; Sliwinska, M.; Magalska, A.; Kadloff, M.; Wolny, A.; Parteka, Z.; Arabasz, S.; Kiss- Arabasz, M.; Plewczynski, D.; Ruan, Y.; Wilczynski, G. M.

10.1101/2020.02.05.935106 — genomics — Posted on 2020-02-06

3088 Vector genetics, insecticide resistance and gene drives: an agent-based modeling approach to evaluate malaria transmission and elimination

Selvaraj, P.; Wenger, E. A.; Bridenbecker, D.; Windbichler, N.; Russell, J. R.; Gerardin, J.; Bever, C. A.; Nikolov, M.

10.1101/2020.01.27.920421 — genetics — Posted on 2020-02-06

3089 Insulin-like signalling influences the coordination of Drosophila larval hemocyte number with body size

Bakopoulos, D.; Forbes-Beadle, L.; Esposito, K. M.; Mirth, C. K.; Warr, C. G.; Johnson, T. K.

10.1101/2020.02.05.935098 — genetics — Posted on 2020-02-06

3090 A tentacle for every occasion: comparing the hunting tentacles and sweeper tentacles, used for territorial competition, in the coral Galaxea fascicularis

Yosef, O.; Popovits, Y.; Malik, A.; Ofek-Lalzer, M.; Mass, T.; Sher, D. J.

10.1101/2020.02.05.936005 — ecology — Posted on 2020-02-06

3091 SIAMCAT: user-friendly and versatile machine learning workflows for statistically rigorous microbiome analyses

Wirbel, J.; Zych, K.; Essex, M.; Karcher, N.; Kartal, E.; Salazar, G.; Bork, P.; Sunagawa, S.; Zeller, G.

10.1101/2020.02.06.931808 — bioinformatics — Posted on 2020-02-06

3092 Method for inferring migration routes from phylogenetic trees

Bermudez, J.

10.1101/2020.02.06.937508 — bioinformatics — Posted on 2020-02-06

3093 Lateral gene transfer drives metabolic flexibility in the anaerobic methane oxidising archaeal family Methanoperedenaceae

McIlroy, S. J.; Leu, A. O.; Ye, J.; Parks, D. H.; Orphan, V.; Tyson, G. W.

10.1101/2020.02.06.936641 — microbiology — Posted on 2020-02-06

3094 Fluctuation, correlation and perturbation-response behavior of nature-made and artificial nanobodies

Hacisuleyman, A.; Erman, B.; Erkip, A.; Erman, B.

10.1101/2020.02.06.936856 — biophysics — Posted on 2020-02-06

3095 Arbitrary Boolean logical search operations on massive molecular file systems

Banal, J. L.; Shepherd, T. R.; Berleant, J. D.; Huang, H.; Reyes, M.; Ackerman, C. M.; Blainey, P.; Bathe, M.

10.1101/2020.02.05.936369 — bioengineering — Posted on 2020-02-06

3096 Growth differentiation factor-15 is associated with age-related monocyte immunosenescence

Pence, B. D.; Yarbro, J. R.; Emmons, R. S.

10.1101/2020.02.05.935643 — immunology — Posted on 2020-02-06

3097 Oxytocin has sex-specific effects on social behaviour and hypothalamic oxytocin immunoreactive cells but not hippocampal neurogenesis in adult rats.

Duarte-Guterman, P.; Lieblich, S. E.; Qiu, W.; Splinter, J. E. J.; Go, K. A.; Casanueva-Reimon, L.; Galea, L. A. M.

10.1101/859165 — neuroscience — Posted on 2020-02-06

3098 An in vivo Probabilistic Atlas of the Human Locus Coeruleus at Ultra-high Field

Ye, R.; Rua, C.; O'Callaghan, C.; Jones, P. S.; Hezemans, F. H.; Kaalund, S. S.; Tsvetanov, K. A.; Rodgers, C.; Williams, G.; Passamonti, L.; Rowe, J.

10.1101/2020.02.03.932087 — neuroscience — Posted on 2020-02-06

3099 Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation

Ali, F.; Shao, L.-X.; Gerhard, D. M.; Sweasy, K.; Pothula, S.; Pittenger, C.; Duman, R. S.; Kwan, A. C.

10.1101/2020.01.07.894832 — neuroscience — Posted on 2020-02-06

3100 Climate change negatively impacts dominant microbes in the sediments of a High Arctic lake

Colby, G. A.; Ruuskanen, M.; St. Pierre, K.; St.Louis, V.; Poulain, A.; Aris-Brosou, S.

10.1101/705178 — microbiology — Posted on 2020-02-06

3101 RIG-I and PKR, but not stress granules, mediate the pro-inflammatory response to Yellow fever virus

Beauclair, G.; Streicher, F.; Bruni, D.; Gracias, S.; Bourgeau, S.; Sinigaglia, L.; Fujita, T.; Meurs, E. F.; Tangy, F.; jouvenet, n.

10.1101/2020.02.05.935486 — microbiology — Posted on 2020-02-06

3102 A paralog-specific role of the COPI pathway in the neuronal differentiation of murine pluripotent cells

Goyal, M.; Zhao, X.; Bozhinova, M.; Andrade-Lopez, K. L.; de Heus, C.; Schulze-Dramac, S.; Mueller-McNicoll, M.; Klumperman, J.; Bethune, J.

10.1101/2020.01.27.921924 — cell biology — Posted on 2020-02-06

3103 Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiate the DNA damage response and repair

Meng, F.; Qian, M.; Peng, B.; Wang, X.; Peng, L.; Zheng, K.; Liu, Z.; Tang, X.; Zhang, S.; Sun, S.; Cao, X.; Pang, Q.; Zhao, B.; Ma, W.; Songyang, Z.; Xu, B.; Zhu, W.-G.; Xu, X.; Liu, B.

10.1101/2020.02.01.930172 — biochemistry — Posted on 2020-02-06

3104 Maternal- and somatic-type snoRNA expression and processing in zebrafish development

Pagano, J. F. B.; Locati, M. D.; Ensink, W. A.; Olst, M. v.; van Leeuwen, S.; De Leeuw, W. C.; Nehrdich, U.; Spaink, H. P.; Rauwerda, H.; Jonker, M. J.; Dekker, R. J.; Breit, T. M.

10.1101/858936 — developmental biology — Posted on 2020-02-06

3105 The Degradation-promoting Roles of Deubiquitinases Ubp6 and Ubp3 in Cytosolic and ER Protein Quality Control

Wu, H.; Ng, D. T. W.; Cheong, I.; Matsudaira, P.

10.1101/2020.01.22.915793 — cell biology — Posted on 2020-02-06

3106 Two-way migration of Lychnis wilfordii caused by the circular landform of Japan-Korea-northeast China-Russian Far East region and its suggestion for conservation in northeast Asia

Tamura, S.; Kwak, M.; Kokubugata, G.; Park, C.-h.; Lee, B.-Y.; Fukuda, T.; Petrunenko, E.; Koksheeva, I.; Pimenova, E.; Krestov, P.; Bondarchuk, S.; Ma, J.-S.; Zhou, H.-C.; Tsuboi, H.; Nishikawa, Y.; Shimamura, T.; Fujita, H.; Nakamura, K.

10.1101/857227 — evolutionary biology — Posted on 2020-02-06

3107 Low-disturbance farming regenerates healthy critical zone towards sustainable agriculture

Deng, F.; Wang, H.; Xie, H.; Bao, X.; He, H.; Zhang, X.; Liang, C.

10.1101/828673 — ecology — Posted on 2020-02-06

3108 Loss of macp{Psi} ribosomal RNA modification is a major feature of cancer

Babaian, A.; Rothe, K.; Girodat, D.; Minia, I.; Djondovic, S.; Milek, M.; Spencer Miko, S. E.; Wieden, H.-J.; Landthaler, M.; Morin, G. B.; Mager, D. L.

10.1101/840132 — cancer biology — Posted on 2020-02-06

3109 Repetita iuvant: repetition facilitates online planning of sequential movements

Ariani, G.; Kwon, Y. H.; Diedrichsen, J.

10.1101/819938 — neuroscience — Posted on 2020-02-06

3110 Deficits in monitoring self-produced speech in Parkinson's disease

Railo, H.; Nokelainen, N.; Savolainen, S.; Kaasinen, V.

10.1101/823674 — neuroscience — Posted on 2020-02-06

3111 Low concordance of short-term and long-term selection responses in experimental Drosophila populations

Langmüller, A. M.; Schlötterer, C.

10.1101/759704 — molecular biology — Posted on 2020-02-06

3112 Influence of plant genotype and soil on the wheat rhizosphere microbiome: Evidences for a core microbiome across eight African and European soils

Simonin, M.; Dasilva, C.; Terzi, V.; Ngonkeu, E. L. M.; Diouf, D.; Kane, A.; Bena, G.; Moulin, L.

10.1101/777383 — ecology — Posted on 2020-02-06

3113 Computational genomics of brain tumors: identification and characterization of glioma candidate biomarkers through multi-omics integrative molecular profiling

Liu, L.; Wang, G.; Wang, L.; Yu, C.; Li, M.; Song, S.; Hao, L.; Ma, L.; Zhang, Z.

10.1101/798785 — bioinformatics — Posted on 2020-02-06

3114 Loop 1 of APOBEC3C regulates its antiviral activity against HIV-1

Jaguva Vasudevan, A. A.; Balakrishnan, K.; Gertzen, C. G. W.; Borveto, F.; Zhang, Z.; Sangwiman, A.; Held, U.; Küstermann, C.; Banerjee, S.; Schumann, G. G.; Häussinger, D.; Bravo, I. G.; Gohlke, H.; Münk, C.

10.1101/2020.02.05.936021 — microbiology — Posted on 2020-02-06

3115 Structural and mechanical remodeling of the cytoskeleton maintains tensional homeostasis in 3D microtissues under acute dynamic stretch

Walker, M.; Rizzuto, P.; Godin, M.; Pelling, A.

10.1101/780312 — biophysics — Posted on 2020-02-06

3116 BIAFLOWS: A collaborative framework to reproducibly deploy and benchmark bioimage analysis workflows

Rubens, U.; Mormont, R.; Baecker, V.; Michiels, G.; Paavolainen, L.; Ball, G.; Unay, D.; Pavie, B.; Chessel, A.; Scholz, L. A.; Maska, M.; Hoyoux, R.; Vandaele, R.; Stanciu, S. G.; Golani, O.; Sladoje, N.; Paul-Gilloteaux, P.; Maree, R.; Tosi, S.

10.1101/707489 — bioinformatics — Posted on 2020-02-06

3117 Training and inferring neural network function with multi-agent reinforcement learning

Chalk, M.; Tkacik, G.; Marre, O.

10.1101/598086 — neuroscience — Posted on 2020-02-06

3118 Reconciling the potentially irreconcilable? Genotypic and phenotypic amoxicillin-clavulanate resistance in Escherichia coli

Davies, T. J.; Stoesser, N.; Sheppard, A. E.; Abuoun, M.; Fowler, P. W.; Swann, J.; Quan, P.; Griffiths, D.; Vaughan, A.; Morgan, M.; Phan, H. T. T.; Jeffery, K. J.; Andersson, M.; Ellington, M.; Ekelund, O.; Woodford, N.; Mathers, A.; Bonomo, R.; Crook, D. W.; Peto, T. E.; Anjum, M.; Walker, A. S.

10.1101/511402 — microbiology — Posted on 2020-02-06

3119 Field-testing olfactory ability to understand human olfactory ecology

Hoover, K. C.; Botescu, D.; Fedurek, P.; Aarts, S.; Berbesque, J. C.

10.1101/270744 — ecology — Posted on 2020-02-06

3120 Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association

Mohammad-Beigi, H.; Hayashi, Y.; Zeuthen, C. M.; Eskandari, H.; Scavenius, C.; Juul-Madsen, K.; Vorup-Jensen, T.; Enghild, J. J.; Sutherland, D. S.

10.1101/2020.02.05.924480 — pharmacology and toxicology — Posted on 2020-02-06

3121 A non-canonical chemical feedback self-limits nitric oxide-cyclic GMP signaling in health and disease

Dao, V. T.-V.; Elbatreek, M. H.; Deile, M.; Nedvetsky, P. I.; Güldner, A.; Ibarra, C.; Gödecke, A.; Schmidt, H. H. H. W.

10.1101/383208 — pharmacology and toxicology — Posted on 2020-02-06

3122 The metal binding site composition of the cation diffusion facilitator protein MamM cytoplasmic domain impacts its metal responsivity

Barber-Zucker, S.; Shahar, A.; Kolusheva, S.; Zarivach, R.

10.1101/2020.02.06.936617 — biophysics — Posted on 2020-02-06

3123 Native ribonucleases process sgRNA transcripts to create catalytic Cas9/sgRNA complexes in planta

Cody, W. B.; Scholthof, H. B.

10.1101/2020.02.06.937003 — plant biology — Posted on 2020-02-06

3124 Structures of α-synuclein filaments from multiple system atrophy

Schweighauser, M.; Shi, Y.; Tarutani, A.; Kametani, F.; Murzin, A. G.; Ghetti, B.; Matsubara, T.; Tomita, T.; Ando, T.; Hasegawa, K.; Murayama, S.; Yoshida, M.; Hasegawa, M.; Scheres, S. H. W.; Goedert, M.

10.1101/2020.02.05.935619 — neuroscience — Posted on 2020-02-06

3125 Prediction of meiosis-essential genes based upon the dynamic proteomes responsive to spermatogenesis

Fang, K.; Li, Q.; Wei, Y.; Shen, J.; Guo, W.; Zhou, C.; Wu, R.; Ying, W.; Yu, L.; Zi, J.; Zhang, Y.; Yang, H.; Liu, S.; Chen, C. D.

10.1101/2020.02.05.936435 — developmental biology — Posted on 2020-02-06

3126 A glucose starvation response governs endocytic trafficking and eisosomal retention of surface cargoes

Laidlaw, K. M. E.; Bisinski, D. D.; Shashkova, S.; Paine, K. M.; Veillon, M. A.; Leake, M. C.; MacDonald, C.

10.1101/2020.02.05.936187 — cell biology — Posted on 2020-02-06

3127 The versatility of Ascorbate Peroxidase-aided mapping uncovers insights of thenuclear lamina interactions and function

Tran, J. R.; Paulson, D. I.; Moresco, J. J.; Adam, S. A.; Yates, J. R.; Goldman, R. D.; Zheng, Y.

10.1101/2020.02.05.935635 — cell biology — Posted on 2020-02-06

3128 Measuring nucleus mechanics within a living multicellular organism: Physical decoupling and attenuated recovery rate are physiological protective mechanisms of the cell nucleus under high mechanical load

Zuela-Sopilniak, N.; Bar-Sela, D.; Charar, C.; Wintner, O.; Gruenbaum, Y.; Buxboim, A.

10.1101/2020.02.05.935395 — cell biology — Posted on 2020-02-06

3129 P4HA2, a prognostic factor, promotes glioma proliferation, invasion, migration and EMT through collagen regulation and PI3K/AKT pathway

Lin, J.; Wu, X.; Wei, W.; Jin, M.; Cui, Y.; Jin, W.; Qiu, G.

10.1101/2020.02.05.935221 — cancer biology — Posted on 2020-02-06

3130 Targeting nuclear pore protein, NUP210, reduces metastasis through heterochromatin-mediated silencing of mechanosensitive genes

Amin, R.; Shukla, A.; Zhu, J. J.; Kim, S.; Wang, P.; Tian, S. Z.; Cappell, S. D.; Burkett, S.; Liu, H.; Lee, M. P.; Tran, A. D.; Kruhlak, M. J.; Hager, G. L.; Ruan, Y.; Hunter, K. W.

10.1101/2020.02.05.936518 — cancer biology — Posted on 2020-02-06

3131 Nonspecific membrane interactions can modulate BK channel activation

Yazdani, M.; Zhang, G.; Jia, Z.; Shi, J.; Cui, J.; Chen, J.

10.1101/2020.02.05.936161 — biophysics — Posted on 2020-02-06

3132 Integrating smFRET, SAXS and NMR data to infer structural ensembles of an intrinsically-disordered protein

Gomes, G.-N. W.; Krzeminski, M.; Martin, E.; Mittag, T.; Head-Gordon, T.; Forman-Kay, J.; Gradinaru, C.

10.1101/2020.02.05.935890 — biophysics — Posted on 2020-02-06

3133 Effects of Gold Nanoparticles on the Stepping Trajectories of Kinesin

Hasnain, S.; Mugnai, M. L.; Thirumalai, D.

10.1101/2020.02.05.935791 — biophysics — Posted on 2020-02-06

3134 Widespread diversity in the transcriptomes of functionally divergent limb tendons

Disser, N. P.; Ghahramani, G. C.; Swanson, J. B.; Wada, S.; Chao, M. L.; Rodeo, S. A.; Oliver, D. J.; Mendias, C. L.

10.1101/2019.12.18.881797 — systems biology — Posted on 2020-02-06

3135 Optimal anticipatory control as a theory of motor preparation: a thalamo-cortical circuit model

Kao, T.-C.; Sadabadi, M. S.; Hennequin, G.

10.1101/2020.02.02.931246 — neuroscience — Posted on 2020-02-06

3136 Pathway Mining and Data Mining in Functional Genomics. An Integrative Approach to Delineate Boolean Relationships between Src and Its Targets

Piran, M.; Fernandes, P. L.; Sepahi, N.; Piran, M.; Rahimi, A.; Ghanbariasad, A.

10.1101/2020.01.25.919639 — bioinformatics — Posted on 2020-02-06

3137 sgRNA level determines CRISPRi knockdown efficiency in K562 cells

Wang, Y.; Dong, Z.; Jiang, X.; Gong, P.; Lu, J.; Wan, F.

10.1101/2020.01.12.903625 — cancer biology — Posted on 2020-02-06

3138 RNA structure prediction using positive and negative evolutionary information

Rivas, E.

10.1101/2020.02.04.933952 — bioinformatics — Posted on 2020-02-06

3139 Enhancing Intracellular Concentration and Target Engagement of PROTACs with Reversible Covalent Chemistry

Guo, W.-H.; Qi, X.; Liu, Y.; Chung, C.-I.; Bai, F.; Lin, X.; Lu, D.; Wang, L.; Chen, J.; Nomie, K. J.; Li, F.; Wang, M. C.; Shu, X.; Onuchic, J. N.; Woyach, J. A.; Wang, M. L.; Wang, J.

10.1101/2019.12.30.873588 — pharmacology and toxicology — Posted on 2020-02-06

3140 Relating quantitative 7T MRI across cortical depths to cytoarchitectonics, gene expression and connectomics: a framework for tracking neurodegenerative disease

McColgan, P.; helbling, S.; Vaculciakova, L.; Pine, K.; Wagstyl, K.; Attar, F. M.; Edwards, L. J.; Papoutsi, M.; Wei, Y.; van den Heuvel, M.; Tabrizi, S. J.; Rees, G.; Weiskopf, N.

10.1101/2020.02.05.935080 — neuroscience — Posted on 2020-02-06

3141 Human CD8+ T-cells Require Glycolysis to Elicit Effector Function

Stimpson, S. E.; Chen, J.; Newby, B. N.; Khattri, R.; Chapman, H. D.; Angelini, T. E.; Merritt, M. E.; Serreze, D. V.; Mathews, C. E.

10.1101/2020.02.05.935627 — immunology — Posted on 2020-02-06

3142 Scleraxis-Lineage Cell Depletion Improves Tendon Healing

Best, K. T.; Mora, K. E.; Knapp, E.; Buckley, M. R.; Loiselle, A. E.

10.1101/2020.02.01.930255 — cell biology — Posted on 2020-02-06

3143 Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits

Gezer, A. O.; Kochmanski, J.; VanOeveren, S. E.; Cole-Strauss, A.; Kemp, C. J.; Patterson, J. R.; Miller, K. M.; Kuhn, N. C.; Herman, D. E.; McIntire, A.; Lipton, J. W.; Luk, K.; Fleming, S. M.; Sortwell, C. E.; Bernstein, A. I.

10.1101/2020.02.03.932681 — neuroscience — Posted on 2020-02-06

3144 Obesity: can environmental food odours make you lose control? Investigation of implicit priming effects on reactivity and inhibitory control towards foods

MAS, M.; Brindisi, M.-C.; Chabanet, C.; Chambaron, S.

10.1101/2020.01.27.920967 — neuroscience — Posted on 2020-02-06

3145 Differential proteomic analysis by SWATH-MS unravels the most dominant mechanisms underlying yeast adaptation to non-optimal temperatures under anaerobic conditions

Pinheiro, T.; Lip, K. Y. F.; Garcia-Rios, E.; Querol, A.; Teixeira, J. A.; van Gulik, W.; Guillamon, J. M.; Domingues, L.

10.1101/2020.01.06.895581 — microbiology — Posted on 2020-02-06

3146 Using visual encounter data to improve capture-recapture abundance estimates

Joseph, M. B.; Knapp, R. A.

10.1101/2020.01.22.915314 — ecology — Posted on 2020-02-06

3147 senSCOPE: Modeling radiative transfer and biochemical processes in mixed canopies combining green and senescent leaves with SCOPE

Pacheco-Labrador, J.; El-Madany, T. S.; van der Tol, C.; Martin, M. P.; Gonzalez-Cascon, R.; Perez-Priego, O.; Guan, J.; Moreno, G.; Carrara, A.; Reichstein, M.; Migliavacca, M.

10.1101/2020.02.05.935064 — ecology — Posted on 2020-02-06

3148 Mitochondrial protein interaction landscape of SS-31

Chavez, J. D.; Tang, X.; Campbell, M. D.; Reyes, G.; Kramer, P. A.; Stuppard, R.; Keller, A.; Marcinek, D. J.; Bruce, J. E.

10.1101/739128 — systems biology — Posted on 2020-02-06

3149 Effects of spatial heterogeneity on bacterial genetic circuits

Barajas, C.; Del Vecchio, D.

10.1101/2019.12.22.886473 — synthetic biology — Posted on 2020-02-06

3150 Quantitative interactions drive Botrytis cinerea disease outcome across the plant kingdom

Caseys, C.; Shi, G.; Soltis, N.; Gwinner, R.; Corwin, J.; Atwell, S.; Kliebenstein, D.

10.1101/507491 — plant biology — Posted on 2020-02-06

3151 Recycling of energy dissipated as heat accounts for high activity of Photosystem II

Zubik, M.; Luchowski, R.; Kluczyk, D.; Grudzinski, W. H.; Maksim, M.; Nosalewicz, A.; Gruszecki, W. I.

10.1101/842591 — plant biology — Posted on 2020-02-06

3152 The Neurovascular Basis of Postictal Amnesia

Farrell, J. S.; Colangeli, R.; Dudok, B.; Wolff, M. D.; Nguyen, S. L.; Dickson, C. T.; Soltesz, I.; Teskey, G. C.

10.1101/2020.01.30.926717 — neuroscience — Posted on 2020-02-06

3153 microRNA-seq of cartilage reveals an over-abundance of miR-140-3p which contains functional isomiRs

Woods, S.; Charlton, S.; Cheung, K.; Hao, Y.; Soul, J.; Reynard, L. N.; Crowe, N.; Swingler, T. E.; Skelton, A. J.; Pirog, K. A.; Miles, C. G.; Tsompani, D.; Jackson, R. M.; Dalmay, T.; Clark, I. M.; Barter, M. J.; Young, D. A.

10.1101/2020.01.29.925206 — molecular biology — Posted on 2020-02-06

3154 GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline

Guerra-Assuncao, J. A.; Conde, L.; Moghul, I.; Webster, A. P.; Ecker, S.; Chervova, O.; Chatzipantsiou, C.; Prieto, P. P.; Beck, S.; Herrero, J.

10.1101/2020.01.06.873026 — bioinformatics — Posted on 2020-02-06

3155 Transcription factor enrichment analysis (TFEA): Quantifying the activity of hundreds of transcription factors from a single experiment

Rubin, J. D.; Stanley, J. T.; Sigauke, R. F.; Levandowski, C. B.; Maas, Z. L.; Westfall, J.; Taatjes, D. J.; Dowell, R. D.

10.1101/2020.01.25.919738 — bioinformatics — Posted on 2020-02-06

3156 cando.py: Open source software for predictive bioanalytics of large scale drug-protein-disease data

Mangione, W.; Falls, Z.; Chopra, G.; Samudrala, R.

10.1101/845545 — bioinformatics — Posted on 2020-02-06

3157 Data architecture for a large-scale neuroscience collaboration

10.1101/827873 — neuroscience — Posted on 2020-02-06

3158 Regulation of perceptual learning by chronic chemogenetic manipulation of parvalbumin-positive interneurons

Cisneros-Franco, J. M.; Thomas, M. E.; Regragui, I.; Lane, C. P.; Ouellet, L.; de Villers-Sidani, E.

10.1101/2020.01.13.905257 — neuroscience — Posted on 2020-02-06

3159 Genome-wide changes in genetic diversity in a population of Myotis lucifugus affected by white-nose syndrome

Lilley, T.; Wilson, I.; Field, K. A.; Reeder, D. M.; Vodzak, M. E.; Turner, G. G.; Kurta, A.; Blomberg, A. S.; Hoff, S.; Herzog, C.; Paterson, S.

10.1101/764647 — evolutionary biology — Posted on 2020-02-06

3160 Chemokine Signatures Of Pathogen-Specific T Cells I: Effector T Cells

Eberlein, J.; Davenport, B.; Nguyen, T.; Victorino, F.; Jhun, K.; van der Heide, V.; Kuleshov, M.; Maayan, A.; Kedl, R.; Homann, D.

10.1101/2020.02.05.935502 — immunology — Posted on 2020-02-05

3161 GENVISAGE: Rapid Identification of Discriminative and Explainable Feature Pairs for Genomic Analysis

Huang, S.; Blatti, C.; Sinha, S.; Parameswaran, A.

10.1101/2020.02.05.935411 — bioinformatics — Posted on 2020-02-05

3162 Soil microbiota influences clubroot disease by modulating Plasmodiophora brassicae and Brassica napus transcriptomes

Daval, S.; Gazengel, K.; Belcour, A.; Linglin, J.; Guillerm-Erckelboudt, A.-Y.; Sarniguet, A.; Manzanares-Dauleux, M. J.; Lebreton, L.; Mougel, C.

10.1101/2020.02.05.935510 — pathology — Posted on 2020-02-05

3163 Human-induced changes in habitat preference by capybaras (Hydrochoerus hydrochaeris) and their potential effect on zoonotic disease transmission

Dias, T. d. C.; Stabach, J. A.; Huang, Q.; Labruna, M. B.; Leimgruber, P.; Ferraz, K. M. P. M. B.; Lopes, B.; Luz, H. R.; Costa, F. B.; Benatti, H. R.; Correa, L. R.; Nievas, A. M.; Monticelli, P. F.; Piovezan, U.; Szabo, M. P. J.; Aguiar, D. M.; Brites-Neto, J.; Port-Carvalho, M.; Rocha, V. J.

10.1101/2020.02.05.935445 — ecology — Posted on 2020-02-05

3164 Unveiling Prognostics Biomarkers of Tyrosine Metabolism Reprogramming in Liver Cancer by Cross-platform Gene Expression Analyses

Nguyen, T. N.; Le, D.-H.; Nguyen, H. Q.

10.1101/2020.02.05.935429 — cancer biology — Posted on 2020-02-05

3165 Impact of Cancer-Associated Mutations in Hsh155/SF3b1 HEAT Repeats 9-12 on pre-mRNA Splicing in Saccharomyces cerevisiae

Kaur, H.; Groubert, B.; Paulson, J.; McMillan, S.; hoskins, a.

10.1101/2020.02.05.935452 — biochemistry — Posted on 2020-02-05

3166 Evaluation of the inhibitory effects of drugs on the growth of Babesia Parasites using real-time PCR method

Zhai, X.-h.; Feng, X.-x.; Wu, X.; He, W.-h.; Li, Y.-y.; Yao, D.-W.; Zhang, B.

10.1101/2020.02.05.935478 — zoology — Posted on 2020-02-05

3167 Disapproval from romantic partners, friends and parents: source of criticism regulates prefrontal cortex activity

Neoh, M. J.-Y.; Azhari, A.; Mulatti, C.; Bornstein, M. H.; Esposito, G.

10.1101/2020.02.05.935460 — neuroscience — Posted on 2020-02-05

3168 A micro-PRNT for the detection of Ross River virus antibodies in mosquito blood meals: a useful tool for inferring transmission pathways

Gyawali, N.; Murphy, A.; Hugo, L. E.; Devine, G. J.

10.1101/2020.02.05.935437 — microbiology — Posted on 2020-02-05

3169 RIG-I and PKR, but not stress granules, mediate the pro-inflammatory response to Yellow fever virus

Beauclair, G.; Streicher, F.; Bruni, D.; Bourgeau, S.; Gracias, S.; Sinigaglia, L.; Fujita, T.; Meurs, E. F.; Tangy, F.; jouvenet, n.

10.1101/2020.02.05.935486 — microbiology — Posted on 2020-02-05

3170 Discovery of 20 novel ribosomal leaders in bacteria and archaea

Eckert, I.; Weinberg, Z.

10.1101/2020.01.29.924993 — bioinformatics — Posted on 2020-02-05

3171 Study of the Influence of Preprint in bioRχiv for Peer Review and Acceptance Time of PLOS ONE

Hiroyuki, T.; Yuan, S.; Masaki, N.; Xiaomin, L.; Kou, A.

10.1101/2020.01.28.920546 — scientific communication and education — Posted on 2020-02-05

3172 Attractor-like spatial representations in the Subicular Complex network

Sharma, A.; Nair, I. R.; Doreswamy, Y.

10.1101/2020.02.05.935379 — neuroscience — Posted on 2020-02-05

3173 Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

Toombs, J.; Panther, L.; Ornelas, L.; Liu, C.; Gomez, E.; Martinibanez, R.; Cox, S. R.; Ritchie, S. J.; Harris, S. E.; Taylor, A.; Redmond, P.; Russ, T. C.; Murphy, L.; Cooper, J. D.; Burr, K.; Selvaraj, B. T.; Browne, C.; Svendsen, C. N.; Cowley, S. A.; Deary, I.; Chandran, S.; Spires-Jones, T.; Sareen, D.

10.1101/2020.02.05.935213 — cell biology — Posted on 2020-02-05

3174 Soil microbiota influences clubroot disease by modulating Plasmodiophora brassicae and Brassica napus transcriptomes

Daval, S.; Gazengel, K.; Belcour, A.; Linglin, J.; Guillerm-Erckelboudt, A.-Y.; Sarniguet, A.; Manzanares-Dauleux, M. J.; Lebreton, L.; Mougel, C.

10.1101/2020.02.05.935510 — pathology — Posted on 2020-02-05

3175 A micro-PRNT for the detection of Ross River virus antibodies in mosquito blood meals: a useful tool for inferring transmission pathways

Gyawali, N.; Murphy, A.; Hugo, L. E.; Devine, G. J.

10.1101/2020.02.05.935437 — microbiology — Posted on 2020-02-05

3176 KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation.

Li, J.; Hardy, K.; Olshansky, M.; Barugahare, A.; Gearing, L. J.; Prier, J. E.; Sng, X. Y.; Nguyen, M. L. T.; Piovesan, D.; Russ, B. E.; La Gruta, N. L.; Hertzog, P.; Rao, S.; Turner, S. J.

10.1101/2020.02.03.933218 — immunology — Posted on 2020-02-05

3177 Chemokine Signatures Of Pathogen-Specific T Cells I: Effector T Cells

Eberlein, J.; Davenport, B.; Nguyen, T.; Victorino, F.; Jhun, K.; van der Heide, V.; Kuleshov, M.; Maayan, A.; Kedl, R.; Homann, D.

10.1101/2020.02.05.935502 — immunology — Posted on 2020-02-05

3178 Foxg1 organizes cephalic ectoderm to repress mandibular fate, regulate apoptosis, and pattern the upper jaw

Depew, M. J.; Compagnucci, C.

10.1101/2020.02.05.935189 — developmental biology — Posted on 2020-02-05

3179 Unveiling Prognostics Biomarkers of Tyrosine Metabolism Reprogramming in Liver Cancer by Cross-platform Gene Expression Analyses

Nguyen, T. N.; Le, D.-H.; Nguyen, H. Q.

10.1101/2020.02.05.935429 — cancer biology — Posted on 2020-02-05

3180 Multitask learning for Transformers with application to large-scale single-cell transcriptomes

Pang, M.; Tegner, J.

10.1101/2020.02.05.935239 — genomics — Posted on 2020-02-05

3181 Estimation of the propensity for sexual selection in a cyclical parthenogen

Duneau, D.; Altermatt, F.; Ferdy, J.-B.; Ben-ami, F.; Ebert, D.

10.1101/2020.02.05.935148 — evolutionary biology — Posted on 2020-02-05

3182 A robust and interpretable, end-to-end deep learning model for cytometry data

Hu, Z.; Tang, A.; Singh, J.; Bhattacharya, S.; Butte, A. J.

10.1101/2020.02.05.934521 — bioinformatics — Posted on 2020-02-05

3183 Imputing Single-cell RNA-seq data by combining Graph Convolution and Autoencoder Neural Networks

Rao, J.; Zhou, X.; Lu, Y.; Zhao, H.; Yang, Y.

10.1101/2020.02.05.935296 — bioinformatics — Posted on 2020-02-05

3184 The Potassium Channel Subunit Kvβ1 is Required for Synaptic Facilitation

Cho, I. H.; Panzera, L. C.; Chin, M.; Alpizar, S. A.; Hoppa, M. B.

10.1101/2020.02.05.935163 — neuroscience — Posted on 2020-02-05

3185 Short-term heritable variation cancels hundreds of generations of mutational variance for metabolic traits in Caenorhabditis elegans

Baer, C. F.; Hahn, D.; Johnson, L. M.; Smith, O. J.

10.1101/2020.02.05.935197 — evolutionary biology — Posted on 2020-02-05

3186 RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway

Thillaivillalan, D.; Singh, S.; Killoran, R. C.; Singh, A.; Xu, X.; Shifman, J.; Smith, M. J.

10.1101/2020.02.05.923433 — biochemistry — Posted on 2020-02-05

3187 Combining formal education and citizen science: A case study on students' perceptions of learning and interest in an urban rat project

Aivelo, T.; Huovelin, S.

10.1101/2020.01.27.921395 — scientific communication and education — Posted on 2020-02-05

3188 Critical role of deadenylation in regulating poly(A) rhythms and circadian gene expression

Yao, X.; Kojima, S.; Chen, J.

10.1101/700443 — systems biology — Posted on 2020-02-05

3189 Light-driven ATP production promotes mRNA biosynthesis inside hybrid multi-compartment artificial protocells

Altamura, E.; Albanese, P.; Marotta, R.; Milano, F.; Fiore, M.; Trotta, M.; Stano, P.; Mavelli, F.

10.1101/2020.02.05.933846 — synthetic biology — Posted on 2020-02-05

3190 Protective anti-prion antibodies in human immunoglobulin repertoires

Senatore, A.; Frontzek, K.; Emmenegger, M.; Chincisan, A.; Losa, M.; Reimann, R.; Horny, G.; Guo, J.; Fels, S.; Sorce, S.; Zhu, C.; George, N.; Ewert, S.; Pietzonka, T.; Hornemann, S.; Aguzzi, A.

10.1101/2020.02.05.933721 — neuroscience — Posted on 2020-02-05

3191 senSCOPE: Modeling radiative transfer and biochemical processes in mixed canopies combining green and senescent leaves with SCOPE

Pacheco-Labrador, J.; El-Madany, T. S.; van der Tol, C.; Martin, M. P.; Gonzalez-Cascon, R.; Perez-Priego, O.; Guan, J.; Moreno, G.; Carrara, A.; Reichstein, M.; Migliavacca, M.

10.1101/2020.02.05.935064 — ecology — Posted on 2020-02-05

3192 Learning massive interpretable gene regulatory networks of the human brain by merging Bayesian Networks

Bernaola, N.; Michiels, M.; Larranaga, P.; Bielza, C.

10.1101/2020.02.05.935007 — bioinformatics — Posted on 2020-02-05

3193 MapCaller - An integrated and efficient tool for short-read mapping and variant calling using high-throughput sequenced data

Lin, H.-N.; Hsu, W.-L.

10.1101/783605 — bioinformatics — Posted on 2020-02-05

3194 Constitutive ghrelin receptor activity modulates AMPA receptor traffic and supports memory formation

Ribeiro, L. F.; Catarino, T.; Carvalho, M.; Santos, S. D.; Cortes, L.; Opazo, P. O.; Ribeiro, L. R.; Choquet, D.; Esteban, J. A.; Peca, J.; Carvalho, A. L.

10.1101/2020.02.05.934463 — neuroscience — Posted on 2020-02-05

3195 Relating quantitative 7T MRI across cortical depths to cytoarchitectonics, gene expression and connectomics: a framework for tracking neurodegenerative disease

McColgan, P.; helbling, S.; Vaculciakov, L.; Pine, K.; Wagstyl, K.; Attar, F. M.; Edwards, L. J.; Papoutsi, M.; Wei, Y.; van den Heuvel, M.; Tabrizi, S. J.; Rees, G.; Weiskopf, N.

10.1101/2020.02.05.935080 — neuroscience — Posted on 2020-02-05

3196 Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation

Dimchev, G.; Amiri, B.; Humphries, A. C.; Schaks, M.; Dimchev, V.; Stradal, T. E. B.; Faix, J.; Krause, M.; Way, M.; Falcke, M.; Rottner, K.

10.1101/777326 — cell biology — Posted on 2020-02-05

3197 Reliable data collection in participatory trials to assess digital healthcare apps.

Park, J.; Park, S.; Kim, G.; Kim, K.; Jung, J.; Yoo, S.; Yi, G.-S.; Lee, D.

10.1101/2020.02.05.935049 — bioinformatics — Posted on 2020-02-05

3198 A neural network for online spike classification that improves decoding accuracy

Issar, D.; Williamson, R.; Khanna, S.; Smith, M. A.

10.1101/722934 — neuroscience — Posted on 2020-02-05

3199 When to depart from a stopover site? Time-since-arrival matters more than weather conditions

Roques, S.; Henry, P.-Y.; Guyot, G.; Bargain, B.; Cam, E.; Pradel, R.

10.1101/2020.02.05.933788 — ecology — Posted on 2020-02-05

3200 Alpha Activity Reflects the Magnitude of an Individual Bias in Human Perception

Grabot, L.; Kayser, C.

10.1101/759159 — neuroscience — Posted on 2020-02-05

3201 Cities have a negative impact on navigation ability: evidence from 38 countries

Coutrot, A.; Manley, E.; Yesiltepe, D.; Dalton, R. C.; Wiener, J. M.; Holscher, C.; Hornberger, M.; Spiers, H. J.

10.1101/2020.01.23.917211 — neuroscience — Posted on 2020-02-05

3202 Predicting N-strain coexistence from co-colonization interactions: epidemiology meets ecology and the replicator equation

Madec, S.; Gjini, E.

10.1101/722587 — ecology — Posted on 2020-02-05

3203 The uneasy coexistence of predators and pathogens

Eilersen, A.; Sneppen, K.

10.1101/721506 — ecology — Posted on 2020-02-05

3204 Coexpression enables multi-study cellular trajectories of development and disease

Hie, B.; Cho, H.; Bryson, B.; Berger, B.

10.1101/719088 — bioinformatics — Posted on 2020-02-05

3205 Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells

Edwards, G.; Perkins, G. A.; Kim, K.-Y.; Kong, Y.; Lee, Y.; Choi, S.-H.; Liu, Y.; Skowronska-Krawczyk, D.; Weinreb, R. N.; Zangwill, L.; Strack, S.; Ju, W.-K.

10.1101/790139 — neuroscience — Posted on 2020-02-05

3206 Functional connectivity alterations of the temporal lobe and hippocampus in semantic dementia and Alzheimer's disease

Schwab, S.; Afyouni, S.; Chen, Y.; Han, Z.; Guo, Q.; Dierks, T.; Wahlund, L.-O.; Grieder, M.

10.1101/322131 — neuroscience — Posted on 2020-02-05

3207 Direct Imaging of Liquid Domains in Membranes by Cryo Electron Tomography

Cornell, C. E.; Mileant, A.; Thakkar, N.; Lee, K. K.; Keller, S. L.

10.1101/2020.02.05.935684 — biophysics — Posted on 2020-02-05

3208 Direct label-free imaging of nanodomains in biomimetic and biological membranes by cryogenic electron microscopy

Heberle, F. A.; Doktorova, M.; Scott, H. L.; Skinkle, A. D.; Waxham, N.; Levental, I.

10.1101/2020.02.05.935551 — biophysics — Posted on 2020-02-05

3209 Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by NuRD

Ragheb, R.; Gharbi, S.; Cramard, J.; Ogundele, O.; Kloet, S.; Burgold, T.; Vermeulen, M.; Reynolds, N.; Hendrich, B.

10.1101/2020.02.05.935544 — developmental biology — Posted on 2020-02-05

3210 MiRNA-10b marks aggressive squamous cell carcinomas, and confers a cancer stem cell-like phenotype

Wimmer, M.; Zauner, R.; Ablinger, M.; Pinon-Hofbauer, J.; Guttmann-Gruber, C.; Reisenberger, M.; Lettner, T.; Niklas, N.; Proell, J.; Sajinovic, M.; De Souza, P.; Hainzl, S.; Kocher, T.; Murauer, E. M.; Bauer, J. W.; Strunk, D.; Reichelt, J.; Mellick, A. S.; Wally, V.

10.1101/2020.02.05.934109 — cancer biology — Posted on 2020-02-05

3211 An Animal Model to Study Klebsiella pneumoniae Gastro-Intestinal Colonization and Host-to-Host Transmission

Zafar, M. A.; Young, T. M.; Bray, A. S.; Nagpal, R. K.; Caudell, D. L.; Yadav, H.

10.1101/2020.02.04.934893 — microbiology — Posted on 2020-02-05

3212 NRP2 as an emerging angiogenic player; promoting endothelial cell adhesion and migration by regulating recycling of α5 integrin.

Alghamdi, A. A.; Benwell, C. J.; Atkinson, S. J.; Lambert, J.; Robinson, S. D.

10.1101/744763 — cell biology — Posted on 2020-02-05

3213 Generating Digital Twins with Multiple Sclerosis Using Probabilistic Neural Networks

Walsh, J. R.; Smith, A. M.; Pouliot, Y.; Li-Bland, D.; Loukianov, A.; Fisher, C. K.; Multiple Sclerosis Outcome Assessments Consortium,

10.1101/2020.02.04.934679 — bioinformatics — Posted on 2020-02-05

3214 Disruption of AtHAK/KT/KUP9 enhances plant cesium accumulation under low potassium supply

Genies, L.; Martin, L.; Kanno, S.; Chiarenza, S.; Carasco, L.; Camilleri, V.; Vavasseur, A.; Henner, P.; Leonhardt, N.

10.1101/2020.02.05.931527 — plant biology — Posted on 2020-02-05

3215 Segregation, connectivity, and gradients of deactivation in neural correlates of evidence in social decision making

Viviani, R.; Dommes, L.; Bosch, J.; Labek, K.

10.1101/2020.02.04.934836 — neuroscience — Posted on 2020-02-05

3216 ClgR contributes to pulmonary pathology but not bacterial growth in Mycobacterium tuberculosis infection

Gautam, U. S.; Kaushal, D.

10.1101/2020.02.04.934901 — microbiology — Posted on 2020-02-05

3217 Lactobacillus curvatus Strains Specifically Show High Levels of Tolerance to Freeze-Thaw Stress

Ikai, R.; Tanabe, K.; Shima, J.

10.1101/2020.02.04.934851 — microbiology — Posted on 2020-02-05

3218 Bacterial Growth Stimulation and Antifungal Effects Of The Essential-oil-less-extracts Of The Food Spice Dysphania ambrosioides

Nitsch-Velasquez, L.

10.1101/2020.02.04.934885 — microbiology — Posted on 2020-02-05

3219 Chromonomer: a tool set for repairing and enhancing assembled genomes through integration of genetic maps and conserved synteny

Catchen, J. M.; Amores, A.; Bassham, S.

10.1101/2020.02.04.934711 — genomics — Posted on 2020-02-05

3220 Exon definition facilitates reliable control of alternative splicing in the RON proto-oncogene

Enculescu, M.; Braun, S.; Setty, S. T.; Zarnack, K.; Koenig, J.; Legewie, S.

10.1101/714022 — biophysics — Posted on 2020-02-05

3221 Deep phylo-taxono-genomics (DEEPT genomics) reveals misclassification of Xanthomonas species complexes into Xylella, Stenotrophomonas and Pseudoxanthomonas

Bansal, K.; Kumar, S.; Kaur, A.; Sharma, S.; Patil, P.; Patil, P. B.

10.1101/2020.02.04.933507 — genomics — Posted on 2020-02-05

3222 Short chain fatty acid butyrate promotes virus infection by repressing interferon stimulated genes

Chemudupati, M.; Smith, A.; Fillinger, R.; Kenney, A.; Zhang, L.; Zani, A.; Liu, S.-L.; Anderson, M. Z.; Sharma, A.; Yount, J.

10.1101/2020.02.04.934919 — microbiology — Posted on 2020-02-05

3223 Species level enrichment of AnAOB and associated growth morphology under the effect of key metabolites

Lu, Y.; Natarajan, G.; Nguyen, T. Q. N.; Thi, S. S.; Arumugam, K.; Seviour, T. W.; Williams, R. B. H.; Wuertz, S.; Law, Y.

10.1101/2020.02.04.934877 — ecology — Posted on 2020-02-05

3224 Increased variation in sex organ positions can increase reciprocity and pollination success in heterostylous plant populations

Ganguly, S.; P.M., S.; Barua, D.

10.1101/2020.02.04.934760 — ecology — Posted on 2020-02-05

3225 Joint Inference of Clonal Structure using Single-cell DNA-Seq and RNA-Seq data

Bai, X.; Wan, L.; Xia, C.

10.1101/2020.02.04.934455 — bioinformatics — Posted on 2020-02-05

3226 Aggregation and Disaggregation Features of the Human Proteome

Määttä, T. A.; Rettel, M.; Helm, D.; Stein, F.; Savitski, M. M.

10.1101/2020.02.05.931675 — systems biology — Posted on 2020-02-05

3227 Molecular characterization of differences between the tomato immune receptors Fls3 and Fls2

Roberts, R.; Liu, A. E.; Wan, L.; Geiger, A. M.; Hind, S. R.; Rosli, H. G.; Martin, G. B.

10.1101/2020.02.04.934133 — plant biology — Posted on 2020-02-05

3228 Microstructural meal pattern analysis reveals that nicotine is a potent anti-anorectic drug despite producing long-term anorexigenic effects

Shankar, K.; Ambroggi, F.; George, O.

10.1101/2020.02.04.934414 — physiology — Posted on 2020-02-05

3229 Progesterone shapes medial temporal lobe volume across the human menstrual cycle

Taylor, C. M.; Pritschet, L.; Olsen, R.; Layher, E.; Santander, T.; Grafton, S. T.; Jacobs, E. G.

10.1101/2020.02.04.934141 — neuroscience — Posted on 2020-02-05

3230 Bidirectional synaptic plasticity rapidly modifies hippocampal representations independent of correlated activity

Milstein, A. D.; Li, Y.; Bittner, K. C.; Grienberger, C.; Soltesz, I.; Magee, J. C.; Romani, S.

10.1101/2020.02.04.934182 — neuroscience — Posted on 2020-02-05

3231 A neural circuit for flexible control of persistent behavioral states

Ji, N.; Madan, G. K.; Fabre, G. I.; Dayan, A.; Baker, C. M.; Nwabudike, I.; Flavell, S. W.

10.1101/2020.02.04.934547 — neuroscience — Posted on 2020-02-05

3232 Altered Temporal Variability of Local and Large-scale Resting-state Brain Functional Connectivity Patterns in Schizophrenia and Bipolar Disorder

Long, Y.; Liu, Z.; Chan, C. K.-y.; Wu, G.; Xue, Z.; Pan, Y.; Chen, X.; Huang, X.; Pu, W.

10.1101/2020.02.04.934638 — neuroscience — Posted on 2020-02-05

3233 A new mechanism for a familiar mutation - bovine DGAT1 K232A modulates gene expression through multi-junction exon splice enhancement

Fink, T.; Lopdell, T. J.; Tiplady, K.; Handley, R.; Johnson, T. J.; Spelman, R. J.; Davis, S. R.; Snell, R. G.; Littlejohn, M. D.

10.1101/2020.02.04.934562 — molecular biology — Posted on 2020-02-05

3234 The cell and stress specific dynamics of in vivo and in vitro canonical and non-canonical tRNA cleavage.

Rashad, S.; Abe, T.; Tominaga, T.; Niizuma, K.

10.1101/2020.02.04.934695 — molecular biology — Posted on 2020-02-05

3235 A novel assay to measure the emergence of third-stage filarial nematodes in individual mosquitoes

McCrea, A. R.; Edgerton, E. B.; Oliver, G. T.; O'Neill, F. M.; Nolan, T. J.; Lok, J. B.; Povelones, M.

10.1101/2020.02.04.934653 — microbiology — Posted on 2020-02-05

3236 Neutrophils are required during immunization with the pneumococcal conjugate vaccine for protective antibody responses and host defense against infection

Tchalla, E. Y. I.; Wohlfert, E. A.; Bou Ghanem, E. N.

10.1101/2020.02.04.934380 — immunology — Posted on 2020-02-05

3237 shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination

Petrillo, C.; Barroca, V.; Ribeiro, J.; Lailler, N.; Livera, G.; Keeney, S.; Martini, E.; Jain, D.

10.1101/2020.02.04.934042 — genetics — Posted on 2020-02-05

3238 Morphological defense as a nonlinear trigger in an intraguild predation food web

Mendonça, J. P.; Gleria, I.; Lyra, M. L.

10.1101/2020.02.04.934588 — ecology — Posted on 2020-02-05

3239 Recent and rapid anthropogenic habitat fragmentation increases extinction risk for freshwater biodiversity

Brauer, C.; Beheregaray, L. B.

10.1101/2020.02.04.934729 — ecology — Posted on 2020-02-05

3240 Stem Cell Transplantation Rescued A Primary Open-Angle Glaucoma Mouse Model

Xiong, S.; Kumar, A.; Tian, S.; Taher, E.; Yang, E.; Kinchington, P. R.; Xia, X.; Du, Y.

10.1101/2020.02.04.934448 — developmental biology — Posted on 2020-02-05

3241 EMBER: Multi-label prediction of kinase-substrate phosphorylation events through deep learning

Kirchoff, K. E.; Gomez, S. M.

10.1101/2020.02.04.934216 — bioinformatics — Posted on 2020-02-05

3242 Sputtered porous Pt for wafer-scale manufacture of low-impedance flexible microelectrodes

Fan, B.; Rodriguez, A. V.; Vercosa, D. L.; Kemere, C.; Robinson, J. T.

10.1101/2020.02.04.934737 — bioengineering — Posted on 2020-02-05

3243 The Hedgehog Co-Receptor BOC Differentially Regulates SHH Signaling During Craniofacial Development

Echevarria-Andino, M.; Allen, B.

10.1101/2020.02.04.934497 — developmental biology — Posted on 2020-02-05

3244 BiGen: Integrative Clinical and Brain-Imaging Genetics Analysis Using Structural Equation Model

Elsheikh, S. S. M.; Chimusa, E. R.; Crimi, A.; Mulder, N. J.

10.1101/2020.02.04.934596 — bioinformatics — Posted on 2020-02-05

3245 Physiological and head motion signatures in static and time-varying functional connectivity and their subject discriminability

Xifra-Porxas, A.; Kassinopoulos, M.; Mitsis, G. D.

10.1101/2020.02.04.934554 — neuroscience — Posted on 2020-02-05

3246 Area per player in small-sided games to replicate the external load and estimated physiological match demands in elite soccer players

RIBOLI, A.; Coratella, G.; Rampichini, S.; Ce, E.; Esposito, F.

10.1101/2020.02.03.932954 — physiology — Posted on 2020-02-05

3247 CRNKL1 is a highly selective regulator of intron-retaining HIV-1 and cellular mRNAs

Xiao, H.; Wyler, E.; Milek, M.; Grewe, B.; Kirchner, P.; Ekici, A.; Silva, A. B. O. V.; Jungnickl, D.; Landthaler, M.; Ensser, A.; Überla, K.

10.1101/2020.02.04.934927 — molecular biology — Posted on 2020-02-05

3248 Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

Rastogi, S.; Xue, Y.; Quake, S. R.; Boothroyd, J. C.

10.1101/2020.02.04.934570 — microbiology — Posted on 2020-02-05

3249 The Wsp intermembrane complex mediates metabolic control of the swim-attach decision of Pseudomonas putida

Hueso, M. A.; Calles, B.; de Lorenzo, V.

10.1101/2020.02.05.934950 — microbiology — Posted on 2020-02-05

3250 Exosome-mediated apoptosis pathway during WSSV infection in crustacean mud crab

Gong, Y.; Kong, T.; Ren, X.; Chen, J.; Lin, S.; Zhang, Y.; Li, S.

10.1101/2020.02.03.932970 — immunology — Posted on 2020-02-05

3251 Genetic Disruption of Serine Biosynthesis is a Key Driver of Macular Telangiectasia Type 2 Etiology and Progression

Bonelli, R.; Ansell, B.; Lotta, L.; Scerri, T.; Clemons, T. E.; Leung, I.; The MacTel Consortium, ; Peto, T.; Bird, A. C.; Sallo, F.; Langenberg, C.; Bahlo, M.

10.1101/2020.02.04.934356 — genetics — Posted on 2020-02-05

3252 Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding at cis-regulatory elements and TAD boundaries

Kadota, S.; Ou, J.; Shi, Y.; Sun, J.; Yildirim, E.

10.1101/2020.02.04.934398 — cell biology — Posted on 2020-02-05

3253 Habitat selection drives dietary specialisation in Sorex minutus

Ware, R. L.; Booker, A. L.; Allaby, F. R.; Allaby, R. G.

10.1101/2020.02.03.932913 — ecology — Posted on 2020-02-05

3254 Determining protein structure by tyrosine bioconjugation

Moinpour, M.; Barker, N. K.; Guzman, L. E.; Jewett, J. C.; Langlais, P. R.; Schwartz, J. C.

10.1101/2020.02.04.934406 — biochemistry — Posted on 2020-02-05

3255 Beef cattle that respond differently to fescue toxicosis have distinct gastrointestinal tract microbiota

Koester, L. R.; Poole, D. H.; Serao, N. V.; Schmitz-Esser, S.

10.1101/2020.02.03.932939 — microbiology — Posted on 2020-02-05

3256 Polar opposites; bacterioplankton susceptibility and mycoplankton resistance to ocean acidification

de Scally, S. Z.; Chaffron, S.; Makhalanyane, T. P.

10.1101/2020.02.03.933325 — microbiology — Posted on 2020-02-05

3257 Prevalence of Staphylococcal Superantigens and their association among bacteremic and Infective Endocarditis patients in Egypt

Elsherif, H. M.; Helal, Z. H.; El-Ansary, M. R.; Fahmy, Z. A.; Eltayeb, W. N.; Radwan, S.; Aboshanab, K. M.

10.1101/2020.02.03.932921 — microbiology — Posted on 2020-02-05

3258 Triacylglycerol synthesis enhances macrophage inflammatory function

Castoldi, A.; Monteiro, L. B.; van Teijlingen Bakker, N.; Sanin, D. E.; Rana, N.; Corrado, M.; Cameron, A. M.; Hassler, F.; Matsushita, M.; Caputa, G.; Klein Geltink, R. I. I.; Buscher, J.; Edwards-Hicks, J.; Pearce, E. L.; Pearce, E. J.

10.1101/2020.02.03.932079 — immunology — Posted on 2020-02-05

3259 A genome engineering resource to uncover principles of cellular organization and tissue architecture by lipid signalling

Trivedi, D.; CM, V.; Bisht, K.; Janardan, V.; Pandit, A.; Basak, B.; RAGHu, P.

10.1101/2020.02.03.933093 — genetics — Posted on 2020-02-05

3260 Twist, Snail, and Sox9 form an allosterically regulated complex, the EMTosome, on a bipartite E-box site.

McCracken, D.; Peng, H. P.; Ayyanathan, K.; Jiang, Y. L.; Welsh, S.; Yang, J.; Kennedy, E.; Rauscher, F. J.; Gardini, A.; Rauscher, F. J.

10.1101/2020.02.03.932962 — cancer biology — Posted on 2020-02-05

3261 A quiescent state following mild sensory arousal in Caenorhabditis elegans is potentiated by stress

McClanahan, P. D.; Dubuque, J. M.; Kontogiorgos-Heintz, D.; Habermeyer, B. F.; Xu, J.; Ma, A.; Raizen, D. M.; Fang-Yen, C.

10.1101/784306 — neuroscience — Posted on 2020-02-05

3262 A Comprehensive Assessment of Human Natural Killer Cell Phenotype and Function in Whole Blood

Market, M.; Tennakoon, G.; Ng, J.; Scaffidi, M.; Tanese de Souza, C.; Kennedy, M. A.; Auer, R. C.

10.1101/2020.02.03.932640 — immunology — Posted on 2020-02-05

3263 Hybridizing salamanders experience accelerated diversification

Patton, A.; Margres, M. J.; Epstein, B.; Eastman, J.; Harmon, L. J.; Storfer, A.

10.1101/760264 — evolutionary biology — Posted on 2020-02-05

3264 Group size and collective action in a binary contribution game

Nöldeke, G.; Pena, J.

10.1101/483149 — evolutionary biology — Posted on 2020-02-05

3265 Efficient reaction deletion algorithms for redesignof constraint-based metabolic networks for metabolite production with weak coupling

Tamura, T.

10.1101/563437 — bioinformatics — Posted on 2020-02-05

3266 Genomic variance of the 2019-nCoV coronavirus

Ceraolo, C.; Giorgi, F. M.

10.1101/2020.02.02.931162 — bioinformatics — Posted on 2020-02-05

3267 Phase transition of prion protein initiates proteinase K resistant amyloid formation

Tange, H.; Ishibashi, D.; Nakagaki, T.; Taguchi, Y.; Kamatari, Y. O.; Ozawa, H.; Nishida, N.

10.1101/2020.01.25.919340 — biochemistry — Posted on 2020-02-05

3268 Unexpected complexity of everyday manual behaviors

Yan, Y.; Goodman, J. M.; Moore, D. D.; Solla, S.; Bensmaia, S. J.

10.1101/694778 — neuroscience — Posted on 2020-02-05

3269 Analytical solution of linearized equations of the Morris-Lecar neuron model at large constant stimulation

Paraskevov, A. V.; Zemskova, T. S.

10.1101/869875 — neuroscience — Posted on 2020-02-05

3270 Competitive Inhibition of Cortisol by Prostaglandins at the Ligand Binding Domain of Glucocorticoid Receptors

Schaper, C.

10.1101/851501 — molecular biology — Posted on 2020-02-05

3271 Bacterial community profiling highlights complex diversity and novel organisms in wildlife ticks

Egan, S. L.; Loh, S.-M.; Banks, P. B.; Gillett, A.; Ahlstrom, L. A.; Ryan, U. M.; Irwin, P. J.; Oskam, C. L.

10.1101/807131 — microbiology — Posted on 2020-02-05

3272 Ultra-Efficient Short Read Sequencing of T Cell Receptor Repertoires

Montagne, J.; Zheng, X.; Pinal-Fernandez, I.; Milisenda, J.; Christopher-Stine, L.; Lloyd, T.; Mammen, A.; Larman, H. B.

10.1101/494062 — immunology — Posted on 2020-02-05

3273 A Comprehensive Evaluation of Methods for Mendelian Randomization Using Realistic Simulations and an Analysis of 38 Biomarkers for Risk of Type-2 Diabetes

Qi, G.; Chatterjee, N.

10.1101/702787 — genetics — Posted on 2020-02-05

3274 A mixed-model approach for powerful testing of genetic associations with cancer risk incorporating tumor characteristics

Zhang, H.; Zhao, N.; Ahearn, T. U.; Wheeler, W.; Garcia-Closas, M.; Chatterjee, N.

10.1101/446039 — genetics — Posted on 2020-02-05

3275 TRPV1 expressed throughout the arterial circulation regulates vasoconstriction

Phan, T. X.; Ton, H. T.; Gulyas, H.; Porszasz, R.; Toth, A.; Russo, R.; Kay, M. W.; Sahibzada, N.; Ahern, G. P.

10.1101/2020.02.04.934117 — physiology — Posted on 2020-02-04

3276 Ribosome Profiling in Archaea Reveals Leaderless Translation, Novel Translational Initiation Sites, and Ribosome Pausing at Single Codon Resolution

Gelsinger, D. R.; Dallon, E.; Reddy, R.; Mohammad, F.; Buskirk, A. R.; DiRuggiero, J.

10.1101/2020.02.04.934349 — molecular biology — Posted on 2020-02-04

3277 Immunological role of primary cilia of dendritic cells in human skin disease

Toriyama, M.; Rizaldy, D.; Nakamura, M.; Fujita, F.; Okada, F.; Morita, A.; Ishii, K. J.

10.1101/2020.02.04.933333 — cell biology — Posted on 2020-02-04

3278 Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility

Sanchez-Saez, F.; Gomez-H, L.; Dunne, O. M.; Gallego-Paramo, C.; Felipe-Medina, N.; Sanchez-Martin, M. A.; Llano, E.; Pendas, A. M.; Davies, O. R.

10.1101/2020.02.04.934372 — biochemistry — Posted on 2020-02-04

3279 Unravelling the developmental and functional significance of an ancient Argonaute duplication

Fridrich, A.; Modepalli, V.; Lewandowska, M.; Aharoni, R.; Moran, Y.

10.1101/2020.02.04.933887 — evolutionary biology — Posted on 2020-02-04

3280 Exon 13-skipped USH2A protein retains functional integrity in mice, suggesting an exon skipping therapeutic approach to treat USH2A-associated disease.

Pendse, N.; Lamas, V.; Maeder, M.; Pawlyk, B.; Gloskowski, S.; Pierce, E. A.; Chen, Z.-Y.; Liu, Q.

10.1101/2020.02.04.934240 — molecular biology — Posted on 2020-02-04

3281 A novel mutation in KCNK16 causing a gain-of-function in the TALK-1 potassium channel: a new cause of maturity onset diabetes of the young.

Graff, S.; Johnson, S.; Leo, P.; Dadi, P.; Nakhe, A.; McInerney-Leo, A.; Marshall, M.; Brown, M.; Jacobson, D.; Duncan, E.

10.1101/2020.02.04.929430 — genetics — Posted on 2020-02-04

3282 Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

Wierzbinska, J. A.; Toth, R.; Ishaque, N.; Rippe, K.; Mallm, J.-P.; Klett, L.; Mertens, D.; Zenz, T.; Hielscher, T.; Seifert, M.; Kueppers, R.; Assenov, Y.; Lutsik, P.; Stilgenbauer, S.; Roessner, P. M.; Seiffert, M.; Byrd, J.; Oakes, C. C.; Plass, C.; Lipka, D. B.

10.1101/2020.02.04.933937 — cancer biology — Posted on 2020-02-04

3283 Cell Atlas of Aqueous Humor Outflow Pathways in Eyes of Humans and Four Model Species Provides Insights into Glaucoma Pathogenesis

van Zyl, T.; Yan, W.; McAdams, A.; Peng, Y.-R.; Shekhar, K.; Regev, A.; Juric, D.; Sanes, J. R.

10.1101/2020.02.04.933911 — cell biology — Posted on 2020-02-04

3284 Integrated profiling of single cell epigenomic and transcriptomic landscape of Parkinson's disease mouse brain

Zhong, J.; Tang, G.; Zhu, J.; Qiu, X.; Wu, W.; Li, G.; Lin, X.; Liang, L.; Chai, C.; Zeng, Y.; Wang, F.; Luo, L.; Li, J.; Chen, F.; Huang, Z.; Xu, X.; Tang, S.; Zhu, S.; Chen, D.

10.1101/2020.02.04.933259 — cell biology — Posted on 2020-02-04

3285 Florigen family chromatin recruitment, competition and target genes

Zhu, Y.; Wagner, D.; Klasfeld, S.; Jeong, C. W.; Jin, R.; Goto, K.; Yamaguchi, N.

10.1101/2020.02.04.934026 — plant biology — Posted on 2020-02-04

3286 Genome-resolved metagenomics and detailed geochemical speciation analyses yield new insights into microbial mercury cycling in geothermal springs

Gionfriddo, C.; Stott, M.; Power, J. F.; Ogorek, J. M.; Krabbenhoft, D. P.; Wick, R. R.; Holt, K. E.; Chen, L.-X.; Thomas, B. C.; Banfield, J. F.; Moreau, J. W.

10.1101/2020.02.03.933291 — microbiology — Posted on 2020-02-04

3287 Trophectoderm Potency is Retained Exclusively in Human Naïve Cells

Guo, G.; Stirparo, G. G.; Strawbridge, S.; Yang, J.; Clarke, J.; Li, M. A.; Myers, S.; Ozel, B. N.; Nichols, J.; Smith, A.

10.1101/2020.02.04.933812 — developmental biology — Posted on 2020-02-04

3288 Small heat shock proteins determine synapse number and neuronal activity during development

de los Reyes, T.; Santana, E.; Casas-Tinto, S.

10.1101/2020.02.04.934075 — cell biology — Posted on 2020-02-04

3289 Identification of CDH11 as an ASD risk gene by matched-gene co-expression analysis and mouse behavioral studies

Wu, N.; Pan, Y.-H.; Yuan, X.

10.1101/2020.02.04.931121 — neuroscience — Posted on 2020-02-04

3290 An extension to: Systematic assessment of commercially available low-input miRNA library preparation kits

Heinicke, F.; Zhong, X.; Zucknick, M.; Breidenbach, J.; Sundaram, A. Y. M.; Flam, S. T.; Leithaug, M.; Dalland, M.; Rayner, S.; Lie, B. A.; Gilfillan, G. D.

10.1101/2020.01.25.919431 — molecular biology — Posted on 2020-02-04

3291 Consequences of single-locus and tightly linked genomic architectures for evolutionary responses to environmental change

Oomen, R. A.; Kuparinen, A.; Hutchings, J. A.

10.1101/2020.01.31.928770 — evolutionary biology — Posted on 2020-02-04

3292 Scalable Classification of Organisms into a Taxonomy Using Hierarchical Supervised Learners

Sohsah, G.; Ibrahimzada, A. R.; Ayaz, H.; Cakmak, A.

10.1101/2020.02.04.933374 — bioinformatics — Posted on 2020-02-04

3293 Testing structural identifiability by a simple scaling method

Castro, M.; de Boer, R. J.

10.1101/2020.02.04.933630 — systems biology — Posted on 2020-02-04

3294 The eNOS-dependent S-nitrosylation of the NF-κB subunit p65 has neuroprotective consequences in excitotoxicity

Caviedes, A.; Maturana, B.; Corvalan, K.; Engler, A.; Gordillo, F.; Varas-Godoy, M.; Smalla, K.-H.; Batiz, L. F.; Lafourcade, C. A.; Kaehne, T.; Wyneken, U.

10.1101/2020.02.04.932772 — neuroscience — Posted on 2020-02-04

3295 The key to complexity in interacting systems with multiple strains

Gjini, E.; Madec, S.

10.1101/2020.02.03.932806 — ecology — Posted on 2020-02-04

3296 In cell architecture of the nuclear pore complex and snapshots of its turnover

Allegretti, M.; Zimmerli, C. E.; Rantos, V.; Wilfling, F.; Ronchi, P.; Fung, H. K.; Lee, C.-W.; Hagen, W.; Turonova, B.; Karius, K.; Zhang, X.; Mueller, C.; Schwab, Y.; Mahamid, J.; Pfander, B.; Kosinski, J.; Beck, M.

10.1101/2020.02.04.933820 — biophysics — Posted on 2020-02-04

3297 NeuroSuites-BNs: An open web framework for massive Bayesian networks focused on neuroscience

Michiels, M.; Larranaga, P.; Bielza, C.

10.1101/2020.02.04.934174 — bioinformatics — Posted on 2020-02-04

3298 First study on age and growth of the deep-water Goblin Shark, Mitsukurina owstoni (Jordan, 1898)

Caltabellotta, F.; Siders, Z.; Cailliet, G.; Motta, F. d. S.; Gadig, O.

10.1101/2020.02.04.934281 — zoology — Posted on 2020-02-04

Kamiyama, Y.; Hirotani, M.; Ishikawa, S.; Minegishi, F.; Katagiri, S.; Takahashi, F.; Nomoto, M.; Ishikawa, K.; Kodama, Y.; Tada, Y.; Takezawa, D.; Peck, S. C.; Shinozaki, K.; Umezawa, T.

10.1101/2020.02.04.933978 — plant biology — Posted on 2020-02-04

3300 PRX1, PRX44, and PRX73 are Class-III extensin-related peroxidases that modulates root hair growth in Arabidopsis thaliana

Marzol, E.; Borassi, C.; Estevez, J. M.

10.1101/2020.02.04.932376 — plant biology — Posted on 2020-02-04

3301 What do blind people "see" with retinal prostheses? Observations and qualitative reports of epiretinal implant users

Erickson-Davis, C.; Korzybska, H.

10.1101/2020.02.03.932905 — neuroscience — Posted on 2020-02-04

3302 Sexually divergent effects of social dominance on chronic stress outcomes in mice

Karamihalev, S.; Brivio, E.; Flachskamm, C.; Stoffel, R.; Schmidt, M. V.; Chen, A.

10.1101/2020.02.04.933481 — neuroscience — Posted on 2020-02-04

3303 Hnrnpul1 loss of function affects skeletal and limb development

Blackwell, D. L.; Fraser, S. D.; Caluseriu, O.; Vivori, C.; Gordon, P.; Tyndall, A. V.; Lamont, R. E.; Parboosingh, J. S.; Innes, A. M.; Bernier, F. P.; Childs, S. J.

10.1101/2020.02.04.934257 — developmental biology — Posted on 2020-02-04

3304 Continual inactivation of genes involved in stem cell functional identity stabilizes progenitor commitment

Quinto-Rives, N.; Komori, H.; Janssens, D. H.; Kondo, S.; Dai, Q.; Moore, A. W.; Lee, C.-Y.

10.1101/2020.02.03.931972 — developmental biology — Posted on 2020-02-04

3305 Gα/GSA-1 works upstream of PKA/KIN-1 to regulate calcium signaling and contractility in the Caenorhabditis elegans spermatheca

Castaneda, P. G.; Cecchetelli, A. D.; Pettit, H. N.; Cram, E. J.

10.1101/2020.02.03.932871 — cell biology — Posted on 2020-02-04

3306 Periodicity Scoring of Time Series Encodes Dynamical Behavior of the Tumor Suppressor p53

Moosmueller, C.; Tralie, C. J.; Kooshkbaghi, M.; Belkhatir, Z.; Pouryahya, M.; Reyes, J.; Deasy, J. O.; Tannenbaum, A. R.; Kevrekidis, I. G.

10.1101/2020.02.04.933192 — bioinformatics — Posted on 2020-02-04

3307 RNA structure prediction using positive and negative evolutionary information

Rivas, E.

10.1101/2020.02.04.933952 — bioinformatics — Posted on 2020-02-04

3308 Current achievements and future developments of a novel AI based visual monitoring of beehives in ecotoxicology and for the monitoring of landscape structures.

Tausch, F.; Schmidt, K. L.; Diehl, M.

10.1101/2020.02.04.933580 — animal behavior and cognition — Posted on 2020-02-04

3309 MiRNAs profiling and degradome sequencing between the CMS-line N816S and its maintainer line Ning5m during anther development in pepper (Capsicum annuum L.)

Zhang, H.; Huang, S.; Tan, J.; Chen, X.; Zhang, M.

10.1101/2020.02.04.933473 — plant biology — Posted on 2020-02-04

3310 Impact of an Oomen feeding with a neonicotinoid on daily activity and colony development of honeybees assessed with an AI based monitoring device

Gonsior, G.; Tausch, F.; Schmidt, K. L.; Knaebe, S.

10.1101/2020.02.04.933556 — pharmacology and toxicology — Posted on 2020-02-04

3311 Time cells in the human hippocampus and entorhinal cortex support episodic memory

Umbach, G.; Kantak, P.; Jacobs, J.; Kahana, M. J.; Pfeiffer, B. E.; Sperling, M.; Lega, B.

10.1101/2020.02.03.932749 — neuroscience — Posted on 2020-02-04

3312 Artemisinin-resistant malaria parasites show enhanced transmission to mosquitoes under drug pressure

Witmer, K.; Dahalan, F. A.; Delves, M. J.; Yahiya, S.; Watson, O. J.; Straschil, U.; Chiwcharoen, D.; Sornboon, B.; Pukrittayakamee, S.; Pearson, R. D.; Howick, V.; Lawniczak, M.; White, N. J.; Dondorp, A. M.; Okell, L. C.; Ruecker, A.; Chotivanich, K.; Baum, J.

10.1101/2020.02.04.933572 — microbiology — Posted on 2020-02-04

3313 Crosskingdom growth benefits of fungus-derived phytohormones in Choy Sum

Gu, K.; Pavagadhi, S. I.; Chen, C.-Y.; Yeap, Y. T.; Swarup, S.; Naqvi, N. I.

10.1101/2020.02.04.933770 — microbiology — Posted on 2020-02-04

3314 Dynamic Laser Speckle Imaging meets Machine Learning to enable Rapid Antibacterial Susceptibility Testing (DyRAST)

Zhou, K.; Zhou, C.; Sapre, A.; Pavlock, J. H.; Weaver, A.; Muralidharan, R.; Noble, J.; Kovac, J.; Liu, Z.; Ebrahimi, A.

10.1101/2020.02.04.926071 — microbiology — Posted on 2020-02-04

3315 ZipSeq : Barcoding for Real-time Mapping of Single Cell Transcriptomes

Hu, K. H.; Eichorst, J. P.; McGinnis, C. S.; Patterson, D. M.; Chow, E. D.; Kersten, K.; Jameson, S. C.; Gartner, Z. J.; Rao, A. A.; Krummel, M. F.

10.1101/2020.02.04.932988 — genomics — Posted on 2020-02-04

3316 Space-time dynamics in monitoring neotropical fish communities using eDNA metabarcoding

Sales, N. G.; Wangensteen, O.; Carvalho, D. C.; Deiner, K.; Praebel, K.; Coscia, I.; McDevitt, A.; Mariani, S.

10.1101/2020.02.04.933366 — ecology — Posted on 2020-02-04

3317 Tourism-driven ocean science for sustainable use: A case study of sharks in Fiji

Ward-Paige, C. A.; Brunnschweiler, J.; Sykes, H.

10.1101/2020.02.04.932236 — ecology — Posted on 2020-02-04

3318 Nanobody-directed targeting of optogenetic tools reveals differential regulation of cilia length

Hansen, J. N.; Kaiser, F.; Klausen, C.; Stueven, B.; Chong, R.; Boenigk, W.; Mick, D. U.; Moeglich, A.; Jurisch-Yaksi, N.; Schmidt, F. I.; Wachten, D.

10.1101/2020.02.04.933440 — cell biology — Posted on 2020-02-04

3319 A designer FG-Nup that reconstitutes the selective transport barrier of the Nuclear Pore Complex

Fragasso, A.; de Vries, H. W.; van der Sluis, E. O.; van der Giessen, E.; Onck, P. R.; Dekker, C.

10.1101/2020.02.04.933994 — biophysics — Posted on 2020-02-04

3320 Enhancement of Target Specificity of CRISPR-Cas12a by Using a Chimeric DNA-RNA Guide

Kim, H.; Lee, W.-j.; Kang, S.-H.; Hur, J. K.; Lee, H.; Song, W.; Lim, K.-S.; Park, Y.-H.; Song, B.-S.; Jin, Y. B.; Jun, B.-H.; Lee, D.-S.; Kim, S.-U.; Lee, S. H.

10.1101/2020.02.04.933614 — biochemistry — Posted on 2020-02-04

3321 Cooperative Policing Behavior Regulates Reproductive Division of Labor in a Termite

Sun, Q.; Hampton, J.; Haynes, K.; Zhou, X.

10.1101/2020.02.04.934315 — animal behavior and cognition — Posted on 2020-02-04

3322 Haplotype Threading: Accurate Polyploid Phasing from Long Reads

Schrinner, S.; Serra Mari, R.; Ebler, J. W.; Rautiainen, M.; Seillier, L.; Reimer, J.; Usadel, B.; Marschall, T.; Klau, G. W.

10.1101/2020.02.04.933523 — bioinformatics — Posted on 2020-02-04

3323 Further perceptions of probability: in defence of trial-by-trial updating models

Forsgren, M.; Juslin, P.; van den Berg, R.

10.1101/2020.01.30.927558 — animal behavior and cognition — Posted on 2020-02-04

3324 Warm periods in repeated cold stresses protect Drosophila against ionoregulatory collapse, chilling injury, and reproductive deficits

El-Saadi, M. I.; Ritchie, M. W.; Davis, H. E.; MacMillan, H. A.

10.1101/2020.02.04.934265 — zoology — Posted on 2020-02-04

3325 Prestimulus alpha power is related to the strength of stimulus representation

Barne, L. C.; de Lange, F.; Cravo, A. M.

10.1101/2020.02.04.933382 — neuroscience — Posted on 2020-02-04

3326 Mindfulness meditation experience is associated with increased ability to monitor covert somatosensory attention

Whitmarsh, S.; Jensen, O.; Barendregt, H.

10.1101/2020.02.04.933606 — neuroscience — Posted on 2020-02-04

3327 Insights into Cross-species Evolution of Novel Human Coronavirus 2019-nCoV and Defining Immune Determinants for Vaccine Development

Ramaiah, A.; Arumugaswami, V.

10.1101/2020.01.29.925867 — microbiology — Posted on 2020-02-04

3328 Examination of the efficacy of small genetic panels in genomic conservation of companion animal populations

Sams, A. J.; Ford, B.; Gardner, A.; Boyko, A. R.

10.1101/2020.02.04.934158 — evolutionary biology — Posted on 2020-02-04

3329 The march of the Common Green Iguana (Iguana iguana): early establishment in Singapore and Thailand is facilitated by the pet trade and recreational parks

van den Burg, M. P.; Van Belleghem, S. M.; De Jesus Villanueva, C. N.

10.1101/2020.02.04.933598 — ecology — Posted on 2020-02-04

3330 Preliminary identification of potential vaccine targets for 2019-nCoV based on SARS-CoV immunological studies

Ahmed, S. F.; Quadeer, A. A.; McKay, M. R.

10.1101/2020.02.03.933226 — bioinformatics — Posted on 2020-02-04

3331 Fluorescence-Detected Conformational Changes in Duplex DNA in Open Complex Formation by E. coli RNA Polymerase: Upstream Wrapping and Downstream Bending Precede Clamp Opening and Insertion of the Downstream Duplex

Sreenivasan, R.; Shkel, I. A.; Chhabra, M.; Drennan, A.; Heitkamp, S.; Wang, H.-C.; Sridevi, M. A.; Plaskon, D.; McNerney, C.; Callies, K.; Cimperman, C. K.; Record, M. T.

10.1101/2020.02.04.932780 — biochemistry — Posted on 2020-02-04

3332 Preservation and changes in oscillatory dynamics across the cortex

Lundqvist, M.; Bastos, A. M.; Miller, E. K.

10.1101/2020.02.03.932533 — neuroscience — Posted on 2020-02-04

3333 Common variation at the LRRK2 locus is associated with survival in the primary tauopathy progressive supranuclear palsy

Jabbari, E.; Tan, M. M. X.; Reynolds, R. H.; Mok, K. Y.; Ferrari, R.; Murphy, D. P.; Valentino, R. R.; Ross, O. A.; Dickson, D. W.; Al-Sarraj, S.; Gentleman, S. M.; Allinson, K. S. J.; Jaunmuktane, Z.; Holton, J. L.; Revesz, T.; Warner, T. T.; Lees, A. J.; Cookson, M. R.; Gibbs, J. R.; Ding, J.; Chia, R.; Traynor, B. J.; Scholz, S. W.; Pantelyat, A.; Viollet, C.; Dalgard, C. L.; Pletnikova, O.; Troncoso, J. C.; Boxer, A. L.; Respondek, G.; Hoglinger, G. U.; Burn, D. J.; Pavese, N.; Gerhard, A.; Kobylecki, C.; Leigh, P. N.; Church, A.; Hu, M. T. M.; Rowe, J. B.; Ryten, M.; Hardy, J.; Shoai, M.;

10.1101/2020.02.04.932335 — genetics — Posted on 2020-02-04

3334 Tensile Force Induced Cytoskeletal Reorganization: Mechanics Before Chemistry

Li, X.; Ni, Q.; He, X.; Kong, J.; Lim, S.-M.; Papoian, G. A.; Trzeciakowski, J. P.; Trache, A.; Jiang, Y.

10.1101/2020.02.03.932863 — cell biology — Posted on 2020-02-04

3335 Machine learning-based analysis of genomes suggests associations between Wuhan 2019-nCoV and bat Betacoronaviruses

Randhawa, G. S.; Soltysiak, M. P. M.; El Roz, H.; de Souza, C. P. E.; Hill, K. A.; Kari, L.

10.1101/2020.02.03.932350 — bioinformatics — Posted on 2020-02-04

3336 Morphological description of the male genital organs of Pontoporia blainvillei (Gervais & d'Orbigny, 1844)

Angrimani, D.; Randi, C. B.; Spinelli, L. G.; de Britto Mari, R.; Bertozzi, C. P.; Guimaraes, J. P.

10.1101/2020.02.03.932897 — zoology — Posted on 2020-02-04

3337 Assessing the impact of physicochemical parameters in the predictive capabilities of thermodynamics-based stoichiometric approaches under mesophilic and thermophilic conditions

Tomi-Andrino, C.; Norman, R.; Millat, T.; Soucaille, P.; Winzer, K.; Barrett, D. A.; King, J.; Kim, D.-H.

10.1101/2020.02.03.932855 — systems biology — Posted on 2020-02-04

3338 Comparative analysis based on transcriptomics and metabolomics data reveal differences between emmer and durum wheat in response to nitrogen starvation

Beleggia, R.; Omranian, N.; Holtz, Y.; Gioia, T.; Fiorani, F.; Nigro, F.; Pecchioni, N.; De Vita, P.; Schurr, U.; David, J.; Nikoloski, Z.; Papa, R.

10.1101/2020.02.03.931717 — plant biology — Posted on 2020-02-04

3339 First report of the bivalves Schedocardia and Acanthocardia (Mollusca, Cardiinae) from Cuba

Orihuela, J.; Ceballos Izquierdo, Y.; Portell, R. W.

10.1101/2020.02.03.932756 — paleontology — Posted on 2020-02-04

3340 Distinct neural variables underlie subjective reports of attention

Whitmarsh, S.; Gitton, C.; Jousmäki, V.; Sackur, J.; Tallon-Baudry, C.

10.1101/2020.01.23.916841 — neuroscience — Posted on 2020-02-04

3341 Prior hypoxia exposure enhances murine microglial inflammatory gene expression in vitro without concomitant H3K4me3 enrichment

Kiernan, E.; Ewald, A.; Ouellette, J.; Wang, T.; Agbeh, A.; Roopra, A.; Watters, J.

10.1101/2020.02.03.933028 — neuroscience — Posted on 2020-02-04

3342 Sharp tuning of head direction by somatosensory fast-spiking interneurons

Long, X.; Young, C. K.; Zhang, S.-J.

10.1101/2020.02.03.933143 — neuroscience — Posted on 2020-02-04

3343 Equivolumetric protocol generates library sizes proportional to total microbial load in next-generation sequencing

Netto Flores Cruz, G.; Christoff, A. P.; Valter de Oliveira, L. F.

10.1101/2020.02.03.932301 — molecular biology — Posted on 2020-02-04

3344 High contiguity long read assembly of Brassica nigra allows localization of active centromeres and provides insights into the ancestral Brassica genome.

Perumal, S.; Koh, C. S.; Jin, L.; Buchwaldt, M.; Higgins, E.; Zheng, C.; Sankoff, D.; Robinson, S. J.; Kagale, S.; Navabi, Z.-K.; Tang, L.; Horner, K. N.; He, Z.; Bancroft, I.; Chalhoub, B.; Sharpe, A. G.; Parkin, I. A.

10.1101/2020.02.03.932665 — genomics — Posted on 2020-02-04

3345 Towards a comparative framework of demographic resilience

Capdevila, P.; Stott, I.; Beger, M.; Salguero-Gomez, R.

10.1101/2020.01.31.928721 — ecology — Posted on 2020-02-04

3346 Machine intelligence design of 2019-nCoV drugs

Nguyen, D. D.; Gao, K.; Wang, R.; Wei, G.

10.1101/2020.01.30.927889 — bioinformatics — Posted on 2020-02-04

3347 Scrutinizing surface glycoproteins and poxin-schlafen protein to design a heterologous recombinant vaccine against monkeypox virus

Hoque, S. F.; Bappy, M. N. I.; Chowdhury, A. T.; Parvez, M. S. A.; Ahmed, F.; Imran, M. A. S.; Azim, K. F.; Hasan, M.

10.1101/2020.01.25.919332 — bioinformatics — Posted on 2020-02-04

3348 Aridity drives coordinated trait shifts but not decreased trait variance across the geographic range of eight Australian trees

Anderegg, L. D. L.; Loy, X.; Markham, I. P.; Elmer, C. M.; Hovenden, J. J.; HilleRisLambers, J.; Mayfield, M. M.

10.1101/2020.02.03.932715 — ecology — Posted on 2020-02-04

George, E. A.; Pimplikar, S.; Thulasi, N.; Brockmann, A.

10.1101/2020.02.02.931345 — animal behavior and cognition — Posted on 2020-02-04

3350 High contiguity de novo genome sequence assembly of Trifoliate yam (Dioscorea dumetorum) using long read sequencing

Siadjeu, C.; Pucker, B.; Viehöver, P.; Albach, D.; Weisshaar, B.

10.1101/2020.01.31.928630 — genomics — Posted on 2020-02-04

3351 Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition

Shen, Y.; Ruggeri, F. S.; Vigolo, D.; Kamada, A.; Qamar, S.; Levin, A.; Iserman, C.; Alberti, S.; St George-Hyslop, P.; Knowles, T.

10.1101/2020.01.21.912857 — biophysics — Posted on 2020-02-04

3352 Understanding Adaptive Immune System as Reinforcement Learning

Kato, T.; Kobayashi, T. J.

10.1101/2020.01.31.929620 — systems biology — Posted on 2020-02-04

3353 Oral Pretreatment with Galantamine Effectively Mitigates the Acute Toxicity of a Supra-Lethal Dose of Soman in Cynomolgus Monkeys Post-treated with Conventional Antidotes

Lane, M.; Carter, D.; Pescrille, J. D.; Aracava, Y.; Fawcett, W. P.; Basinger, G. W.; Pereira, E. F. R.; Albuquerque, E. X.

10.1101/2020.02.03.932798 — pharmacology and toxicology — Posted on 2020-02-04

3354 Cities have a negative impact on navigation ability: evidence from 38 countries

Coutrot, A.; Manley, E.; Yesiltepe, D.; Dalton, R. C.; Wiener, J. M.; Holscher, C.; Hornberger, M.; Spiers, H. J.

10.1101/2020.01.23.917211 — neuroscience — Posted on 2020-02-04

3355 Visualization and normalization of drift effect across batches in metabolome-wide association studies

Bararpour, N.; Gilardi, F.; Carmeli, C.; Sidibe, J.; Ivanisevic, J.; Caputo, T.; Augsburger, M.; Grabherr, S.; Desvergne, B.; Guex, N.; Bochud, M.; Thomas, A.

10.1101/2020.01.22.914051 — bioinformatics — Posted on 2020-02-04

3356 Toxic effect of 2,2'-bis(bicyclo heptane) on bacterial cells.

Kessenikh, A. G.; Gnuchikh, E. Y.; Bazhenov, S. V.; Bermeshev, M. V.; Pevgov, V. G.; Shorunov, S. V.; Samoilov, V. O.; Maksimov, A. L.; Yaguzhinsky, L. S.; Manukhov, I.

10.1101/2020.01.21.913699 — pharmacology and toxicology — Posted on 2020-02-04

3357 A tradeoff between robustness to environmental fluctuations and speed of evolution

Schmid, M.; Paniw, M.; Postuma, M.; Ozgul, A.; Guillaume, F.

10.1101/834234 — evolutionary biology — Posted on 2020-02-04

3358 A novel transplantable model of lung cancer associated tissue loss and disrupted muscle regeneration

Arneson, P. C.; Ducharme, A. M.; Doles, J. D.

10.1101/852442 — cancer biology — Posted on 2020-02-04

3359 Super-Beacons: open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy

Pereira, P. M.; Gustafsson, N.; Marsh, M.; Mhlanga, M. M.; Henriques, R.

10.1101/2020.01.20.912311 — biophysics — Posted on 2020-02-04

3360 A virus-encoded protein suppresses methylation of the viral genome in the Cajal body through its interaction with AGO4

Wang, L.; Ding, Y.; He, L.; Zhang, G.; Zhu, J.-K.; Lozano-Duran, R.

10.1101/811091 — plant biology — Posted on 2020-02-04

3361 The immunocytokine L19-TNF eradicates Sarcomas in combination with Chemotherapy or with immune check-point inhibitors

Corbellari, R.; Nadal, L.; Villa, A.; Neri, D.; De Luca, R.

10.1101/830406 — cancer biology — Posted on 2020-02-04

3362 Computational identification of cell-specific variable regions in ChIP-seq data

Andreani, T.; Albrecht, S.; Fontaine, J.-F.; Andrade, M.

10.1101/796383 — bioinformatics — Posted on 2020-02-04

3363 Protein complex stoichiometry and expression dynamics of transcription factors modulate stem cell division

Clark, N. M.; Fisher, A. P.; Berckmans, B.; Van den Broeck, L.; Nelson, E. C.; Nguyen, T. T.; Bustillo-Avendano, E.; Zebell, S. G.; Moreno-Risueno, M.; Simon, R.; Gallagher, K.; Sozzani, R.

10.1101/439331 — plant biology — Posted on 2020-02-04

3364 A Bayesian Generative Model of Vestibular Afferent Neuron Spiking

Paulin, M.; Hoffman, L. F.; Pullar, K. F.

10.1101/2020.02.03.933150 — neuroscience — Posted on 2020-02-04

3365 Structure-Guided Mutagenesis Alters Deubiquitinating Activity 2 and Attenuates Pathogenesis of a Murine Coronavirus

Deng, X.; Chen, Y.; Mielech, A. M.; Hackbart, M.; Kesely, K. R.; Mettelman, R. C.; OBrien, A.; Chapman, M. E.; Mesecar, A. D.; Baker, S. C.

10.1101/782409 — microbiology — Posted on 2020-02-04

3366 Mutational, transcriptional and viral shedding dynamics of the marine turtle fibropapillomatosis tumor epizootic

Yetsko, K.; Farrell, J.; Stammnitz, M. R.; Whitmore, L.; Whilde, J.; Eastman, C. B.; Rollinson Ramia, D.; Thomas, R.; Krstic, A.; Linser, P.; Creer, S.; Carvalho, G.; Burkhalter, B.; Murchison, E. P.; Schnitzler, C.; Duffy, D. J.

10.1101/2020.02.04.932632 — cancer biology — Posted on 2020-02-04

3367 Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits

Gezer, A. O.; Kochmanski, J.; VanOeveren, S. E.; Cole-Strauss, A.; Kemp, C. J.; Patterson, J. R.; Miller, K. M.; Herman, D. E.; McIntyre, A.; Lipton, J. W.; Luk, K.; Fleming, S. M.; Sortwell, C. E.; Bernstein, A. I.

10.1101/2020.02.03.932681 — neuroscience — Posted on 2020-02-04

3368 Accuracy of short tandem repeats genotyping tools in whole exome sequencing data

Halman, A.; Oshlack, A.

10.1101/2020.02.03.933002 — bioinformatics — Posted on 2020-02-04

3369 Neural evidence for the prediction of animacy features during language comprehension: Evidence from MEG and EEG Representational Similarity Analysis

Wang, L.; Wlotko, E.; Alexander, E.; Schoot, L.; Kim, M.; Warnke, L.; Kuperberg, G. R.

10.1101/709394 — neuroscience — Posted on 2020-02-04

3370 Latrophilins are essential for endothelial junctional fluid shear stress mechanotransduction

Tanaka, K.; Prendergast, A.; Hintzen, J.; Kumar, A.; Chung, M.; Koleske, A.; Crawford, J.; Nicoli, S.; Schwartz, M. A.

10.1101/2020.02.03.932822 — molecular biology — Posted on 2020-02-04

3371 Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection

Chai, X.; Hu, L.; Zhang, Y.; Han, W.; Lu, Z.; Ke, A.; Zhou, J.; Shi, G.; Fang, N.; Fan, J.; Cai, J.; Fan, J.; Lan, F.

10.1101/2020.02.03.931766 — genomics — Posted on 2020-02-04

3372 Floral signals evolve in a predictable way under artificial and pollinator selection in Brassica rapa using a G-matrix

Zu, P.; Schiestl, F. P.; Gervasi, D.; Li, X.; Runcie, D.; Guillaume, F.

10.1101/675413 — evolutionary biology — Posted on 2020-02-04

3373 A Quantitative Model of Cellular Decision Making in Direct Neuronal Reprogramming

Merlevede, A.; Drugge, V.; Barker, R. A.; Drouin-Ouellet, J.; Olariu, V.

10.1101/2020.02.04.933713 — systems biology — Posted on 2020-02-04

3374 Tunable genetic devices through simultaneous control of transcription and translation

Bartoli, V.; Meaker, G. A.; di Bernardo, M.; Gorochowski, T. E.

10.1101/711275 — synthetic biology — Posted on 2020-02-04

3375 Subtilase-mediated activation of CLEL peptides involves several processing events in consecutive compartments of the secretory pathway

Stührwohldt, N.; Scholl, S.; Lang, L.; Katzenberger, J.; Schumacher, K.; Schaller, A.

10.1101/483644 — plant biology — Posted on 2020-02-04

3376 Neuromuscular fatigue and recovery after strenuous exercise depends on skeletal muscle size and stem cell characteristics

Baumert, P.; Temple, S.; Stanley, M. J.; Cocks, M.; Strauss, J. A.; Shepherd, S. O.; Drust, B.; Lake, M. J.; Stewart, C. E.; Erskine, R. M.

10.1101/740266 — physiology — Posted on 2020-02-04

3377 Electrophysiology prediction of single neurons based on their morphology

Michiels, M.

10.1101/2020.02.04.933697 — neuroscience — Posted on 2020-02-04

3378 Multiscale dynamic mean field model to relate resting-state brain dynamics with local cortical excitatory-inhibitory neurotransmitter homeostasis in health and disease

Naskar, A.; Vattikonda, A.; Deco, G.; Roy, D.; Banerjee, A.

10.1101/390716 — neuroscience — Posted on 2020-02-04

3379 Reaching around obstacles accounts for uncertainty in coordinate transformations

Abedi Khoozani, P.; Voudouris, D.; Blohm, G.; Fiehler, K.

10.1101/706317 — neuroscience — Posted on 2020-02-04

3380 Multiple links between 5-methylcytosine content of mRNA and translation

Schumann, U.; Zhang, H.-N.; Sibbritt, T.; Pan, A.; Horvath, A.; Gross, S.; Clark, S. J.; Yang, L.; Preiss, T.

10.1101/2020.02.04.933499 — molecular biology — Posted on 2020-02-04

3381 A common problem in the purification of calicivirus raised by molecular sieving: balance between purification and loss of viral particles

Qu, Z.; Kang, H.; Cui, C.; Meng, K.; Zhang, X.; Qu, L.; Meng, G.

10.1101/2020.02.04.933390 — microbiology — Posted on 2020-02-04

3382 Population genomics and pathotypic evaluation of the bacterial leaf blight pathogen of rice reveals rapid evolutionary dynamics of a plant pathogen

Zheng, J.; Song, Z.; Zheng, D.; Hu, H.; Liu, H.; Zhao, Y.; Sun, M.; Ruan, L.; Liu, F.

10.1101/704221 — genomics — Posted on 2020-02-04

3383 Survival of the frequent at finite population size and mutation rate: bridging the gap between quasispecies and monomorphic regimes with a simple model

Khatri, B. S.

10.1101/375147 — evolutionary biology — Posted on 2020-02-04

3384 A flexible pipeline combining clustering and correction tools for prokaryotic and eukaryotic metabarcoding

Brandt, M. I.; Trouche, B.; Quintric, L.; Wincker, P.; Poulain, J.; Arnaud-Haond, S.

10.1101/717355 — bioinformatics — Posted on 2020-02-04

3385 Sub-lethal insecticide exposure affects host biting efficiency of Kdr-resistant Anopheles gambiae

Diop, M. M.; Chandre, F.; Rossignol, M.; Porciani, A.; Chateau, M.; Moiroux, N.; Pennetier, C.

10.1101/653980 — animal behavior and cognition — Posted on 2020-02-04

3386 Radiation Induced Metabolic Alterations Associate with Tumor Aggressiveness and Poor Outcome in Glioblastoma

Gupta, K.; Vuckovic, I.; Zhang, S.; Xiong, Y.; Carlson, B. L.; Jacobs, J.; Olson, I.; Petterson, X.-M.; Macura, S. I.; Sarkaria, J.; Burns, T.

10.1101/2020.02.04.933648 — cancer biology — Posted on 2020-02-04

3387 Atomic Structure of the LL-37(17-29) Human Antimicrobial Peptide Reveals Functional Helical Fibril

Engelberg, Y.; Landau, M.

10.1101/2020.02.04.933432 — biochemistry — Posted on 2020-02-04

3388 Optoacoustic flow-cytometry with light scattering referencing

Seeger, M.; Stiel, A. C.; Ntziachristos, V.

10.1101/2020.02.04.933705 — biophysics — Posted on 2020-02-04

3389 MetaPhat: Detecting and decomposing multivariate associations from univariate genome-wide association statistics

Lin, J.; Tabassum, R.; Ripatti, S.; Pirinen, M.

10.1101/661421 — genetics — Posted on 2020-02-04

3390 Mesoscopic Liquid Clusters Represent a Distinct Condensate of Mutant p53

Vekilov, P. G.; Yang, D. S.; Saeedi, A.; Davtyan, A.; Fathi, M.; Safari, M.; Klindziuk, A.; Barton, S.; Varadarajan, N.; Kolomeisky, A.

10.1101/2020.02.04.931980 — biophysics — Posted on 2020-02-04

3391 Internally generated population activity in cortical networks hinders information transmission

Huang, C.; Pouget, A.; Doiron, B. D.

10.1101/2020.02.03.932723 — neuroscience — Posted on 2020-02-04

3392 Preservation and changes in oscillatory dynamics across the cortex

Lundqvist, M. K.; Bastos, A. M.; Miller, E. K.

10.1101/2020.02.03.932533 — neuroscience — Posted on 2020-02-04

3393 A Comprehensive Assessment of Human Natural Killer Cell Phenotype and Function in Whole Blood

Market, M.; Tennakoon, G.; Ng, J.; Scaffidi, M.; Tanese de Souza, C.; Kennedy, M. A.; Auer, R. C.

10.1101/2020.02.03.932640 — immunology — Posted on 2020-02-04

3394 The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions

Berger, C. S.; Laroche, J.; Maaroufi, H.; Martin, H.; Moon, K.-M.; Landry, C.; Foster, L.; Aubin-Horth, N.

10.1101/2020.02.03.932509 — genomics — Posted on 2020-02-04

3395 Expression and Pharmacological Inhibition of TrkB and EGFR in Glioblastoma

Pinheiro, K. d. V.; Thomaz, A.; Souza, B. K.; Metcalfe, V. A.; Freire, N. H.; Brunetto, A. T.; de Farias, C. B.; Jaeger, M.; Bambini, V.; Smith, C. G. S.; Shaw, L.; Roesler, R.

10.1101/2020.02.03.932608 — cancer biology — Posted on 2020-02-04

3396 LIVE-PAINT: Super-Resolution Microscopy Inside Live Cells Using Reversible Peptide-Protein Interactions

Oi, C.; Gidden, Z.; Holyoake, L. V.; Kantelberg, O.; Mochrie, S.; Horrocks, M. H.; Regan, L.

10.1101/2020.02.03.932228 — synthetic biology — Posted on 2020-02-04

3397 Genome-Wide Identification and Characterization of MLO Gene Family in Octoploid Strawberry

Tapia, R.; Barbey, C. R.; Chandra, S.; Folta, K. M.; Whitaker, V. M.; Lee, S.

10.1101/2020.02.03.932764 — plant biology — Posted on 2020-02-04

3398 Low aflatoxin levels and flowering delay in Aspergillus flavus-resistant maize lines are correlated with increased corn earworm damage and enhanced seed fumonisin content

Chalivendra, S.; Huang, F.; Busman, M.; Williams, W. P.; Ham, J. H.; Moore, G. G.

10.1101/2020.02.03.933309 — plant biology — Posted on 2020-02-04

Janssen, J.

10.1101/2020.02.04.932210 — neuroscience — Posted on 2020-02-04

3400 The hidden cost of receiving favors: A theory of indebtedness

Gao, X.; Jolly, E.; Yu, H.; Liu, H.; Zhou, X.; Chang, L. J.

10.1101/2020.02.03.926295 — neuroscience — Posted on 2020-02-04

3401 An isothermal method for sensitive detection of Mycobacterium tuberculosis complexes using CRISPR/Cas12a cis- and trans-cleavage

Xu, H.; Zhang, x.; Cai, Z.; Dong, X.; Chen, G.; Li, Z.; Qiu, L.; He, L.; Liu, X.; Liu, J.

10.1101/2020.02.03.933101 — molecular biology — Posted on 2020-02-04

3402 Survival strategies of Enterococcus mundtii in the gut of Spodoptera littoralis : a live report

Mazumdar, T.; Teh, B. S.; Murali, A.; Schmidt-Heck, W.; Vogel, H.; Schlenker, Y.; Boland, W.

10.1101/2020.02.03.932053 — microbiology — Posted on 2020-02-04

3403 Poecivirus is present in individuals with beak deformities in seven species of North American birds

Zylberberg, M.; Van Hemert, C.; Handel, C. M.; Liu, R.; DeRisi, J.

10.1101/2020.02.03.927442 — microbiology — Posted on 2020-02-04

3404 Human cytomegalovirus protein pUL36: a dual cell death pathway inhibitor

Fletcher-Etherington, A.; Nobre, L.; Nightingale, K.; Antrobus, R. J.; Nichols, J.; Davison, A. J.; Stanton, R. J.; Weekes, M. P.

10.1101/2020.02.03.928564 — microbiology — Posted on 2020-02-04

3405 Leukotriene B4 licenses inflammasome activation to enhance skin host defense

Salina, A. C. G.; Brandt, S.; Klopfenstein, N.; Blackman, A.; Byers-Glosson, N.; Brodskyn, C.; Tavares, N. M.; Santos Da Silva, I. B.; Medeiros, A. I.; Serezani, C. H.

10.1101/2020.02.03.932129 — immunology — Posted on 2020-02-04

3406 FAN-C: A Feature-rich Framework for the Analysis and Visualisation of C data

Kruse, K.; Hug, C. B.; Vaquerizas, J. M.

10.1101/2020.02.03.932517 — genomics — Posted on 2020-02-04

3407 Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

Lotta, L. A.; Pietzner, M.; Stewart, I. D.; Wittemans, L. B.; Li, C.; Bonelli, R.; Raffler, J.; Biggs, E. K.; Oliver-Williams, C.; Auyeung, V. P. W.; Surendran, P.; Michelotti, G. A.; Scott, R. A.; Burgess, S.; Zuber, V.; Sanderson, E.; Koulman, A.; Imamura, F.; Forouhi, N.; Khaw, K.-T.; Griffin, J. L.; Wood, A. M.; Kastenmüller, G.; Danesh, J.; Butterworth, A. S.; Gribble, F. M.; Reimann, F.; Bahlo, M.; Fauman, E.; Wareham, N. J.; Langenberg, C.

10.1101/2020.02.03.932541 — genetics — Posted on 2020-02-04

3408 Changes in the tumor microenvironment and treatment outcome in glioblastoma: A pilot study

Ali, S.; Borin, T. F.; Piranlioglu, R.; Ara, R.; Lebedyeva, I.; Angara, K.; Achyut, B. R.; Arbab, A. S.; Rashid, M. H.

10.1101/2020.02.03.932475 — cancer biology — Posted on 2020-02-04

3409 Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme

Kaczmarski, J. A.; Mahawaththa, M. C.; Feintuch, A.; Clifton, B. E.; Adams, L. A.; Goldfarb, D.; Otting, G.; Jackson, C. J.

10.1101/2020.02.03.932491 — biochemistry — Posted on 2020-02-04

3410 Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci

Zhao, Q.; Dacre, M.; Nguyen, T.; Pjanic, M.; Liu, B.; Iyer, D.; Cheng, P.; Wirka, R.; Kim, J. B.; Fraser, H. B.; Quertermous, T.

10.1101/2020.02.03.932368 — genomics — Posted on 2020-02-04

3411 A geometric basis for surface habitat complexity and biodiversity

Torres-Pulliza, D.; Dornelas, M. A.; Pizarro, O.; Bewley, M.; Blowes, S. A.; Boutros, N.; Brambilla, V.; Chase, T. J.; Frank, G.; Friedman, A.; Hoogenboom, M. O.; Williams, S.; Zawada, K. J.; Madin, J. S.

10.1101/2020.02.03.929521 — ecology — Posted on 2020-02-04

3412 Phylogenomic analysis of the 2019-nCoV coronavirus

Ceraolo, C.; Giorgi, F. M.

10.1101/2020.02.02.931162 — bioinformatics — Posted on 2020-02-04

3413 Consistent Effects of Pesticides on Community Structure and Ecosystem Function in Freshwater Systems

Rumschlag, S. L.; Mahon, M.; Hoverman, J.; Raffel, T.; Carrick, H.; Hudson, P.; Rohr, J.

10.1101/2020.02.03.932442 — ecology — Posted on 2020-02-04

3414 Salinomycin inhibits epigenetic modulator EZH2 to enhance Death Receptors in Colon Cancer Stem Cells

Singh, A. K.; Verma, A.; Singh, A.; Arya, R. K.; Maheshwari, S.; Chaturvedi, P.; Nengroo, M. A.; Saini, K. K.; Vishwakarma, A. L.; Singh, K.; Sarkar, J.; Datta, D.

10.1101/2020.02.03.932269 — cancer biology — Posted on 2020-02-04

3415 Genomic analyses reveal the origin of domestic ducks and identify different genetic underpinnings of wild ducks

liu, r.; liu, w.; RONG, E.; Fan, G.; li, n.

10.1101/2020.02.03.933069 — genomics — Posted on 2020-02-04

3416 Targeting STAT3 signalling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer

Simoes, B. M.; Santiago-Gomez, A.; Chiodo, C.; Moreira, T.; Conole, D.; Lovell, S.; Alferez, D.; Eyre, R.; Spence, K.; Sarmiento-Castro, A.; Kohler, B.; Lanzino, M.; Ando, S.; Marangoni, E.; Sims, A. H.; Tate, E. W.; Howell, S. J.; Clarke, R. B.

10.1101/2020.02.03.932194 — cancer biology — Posted on 2020-02-04

3417 Profiling of Human Gut Virome with Oxford Nanopore Technology

Cao, J.; Zhang, Y.; Dai, M.; Xu, J.; Chen, L.; Zhang, F.; Zhao, N.; Wang, J.

10.1101/2020.02.03.933077 — bioinformatics — Posted on 2020-02-04

3418 Prioritizing conservation actions for Pacific salmon in Canada

Walsh, J. C.; Connors, K.; Hertz, E.; Kehoe, L. J.; Martin, T. G.; Connors, B.; Bradford, M. J.; Freshwater, C.; Frid, A.; Halverson, J.; Moore, J. W.; Price, M. H. H.; Reynolds, J. D.

10.1101/2020.02.03.931691 — ecology — Posted on 2020-02-04

3419 Microtubule Assembly and Pole Coalescence: Early Steps in C. elegans Oocyte Meiosis I Spindle Assembly

Chuang, C.-H.; Schlientz, A. J.; Yang, J.; Bowerman, B.

10.1101/2020.02.03.933051 — cell biology — Posted on 2020-02-04

3420 Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients.

Abel, L.; Durmaz, A.; Hu, R.; Longhurst, C.; Scott, J. G.; Kimple, R. J.

10.1101/2020.02.03.930891 — cancer biology — Posted on 2020-02-04

3421 A deep learning approach to identify new gene targets of a novel therapeutic for human splicing disorders

GAO, D.; Morini, E.; Salani, M.; Krauson, A. J.; Ragavendran, A.; Erdin, S.; Logan, E. M.; Chekuri, A.; Li, W.; Dakka, A.; Naryshkin, N.; Trotta, C.; Effenberger, K. A.; Woll, M.; Gabbeta, V.; Karp, G.; Yu, Y.; Johnson, G.; Paquette, W. D.; Talkowski, M. E.; Slaugenhaupt, S. A.

10.1101/2020.02.03.932103 — bioinformatics — Posted on 2020-02-04

3422 EM-net: Deep learning for electron microscopy image segmentation

Khadangi, A.; Boudier, T.; Rajagopal, V.

10.1101/2020.02.03.933127 — bioinformatics — Posted on 2020-02-04

3423 An in vivo Probabilistic Atlas of the Human Locus Coeruleus at Ultra-high Field

Ye, R.; Rua, C.; O'Callaghan, C.; Jones, P. S.; Hezemans, F. H.; Kaalund, S. S.; Tsvetanov, K. A.; Rodgers, C.; Williams, G.; Passamonti, L.; Rowe, J.

10.1101/2020.02.03.932087 — neuroscience — Posted on 2020-02-04

3424 Phenotypic variation within and across transcriptomic cell types in mouse motor cortex

Scala, F.; Kobak, D.; Bernabucci, M.; Bernaerts, Y.; Cadwell, C. R.; Castro, J. R.; Hartmanis, L.; Jiang, X.; Laturnus, S. R.; Miranda, E.; Mulherkar, S.; Tan, Z. H.; Yao, Z.; Zeng, H.; Sandberg, R.; Berens, P.; Tolias, A.

10.1101/2020.02.03.929158 — neuroscience — Posted on 2020-02-04

3425 Toward an integrated classification of neuronal cell types: morphoelectric and transcriptomic characterization of individual GABAergic cortical neurons

Gouwens, N. W.; Sorensen, S. A.; Baftizadeh, F.; Budzillo, A.; Lee, B. R.; Jarsky, T.; Alfiler, L.; Arkhipov, A.; Baker, K.; Barkan, E.; Berry, K.; Bertagnolli, D.; Bickley, K.; Bomben, J.; Braun, T.; Brouner, K.; Casper, T.; Crichton, K.; Daigle, T. L.; Dalley, R.; de Frates, R.; Dee, N.; Desta, T.; Lee, S. D.; Dotson, N.; Egdorf, T.; Ellingwood, L.; Enstrom, R.; Esposito, L.; Farrell, C.; Feng, D.; Fong, O.; Gala, R.; Gamlin, C.; Gary, A.; Glandon, A.; Goldy, J.; Gorham, M.; Graybuck, L.; Gu, H.; Hadley, K.; Hawrylycz, M. J.; Henry, A. M.; Hill, D.; Hupp, M.; Kebede, S.; Kim, T. K.; Kim, L.;

10.1101/2020.02.03.932244 — neuroscience — Posted on 2020-02-04

3426 The influence of QTL allelic diversity on QTL detection in multi-parent populations: a simulation study in sugar beet

Garin, V.; Wimmer, V.; Borchardt, D.; Malosetti, M.; van Eeuwijk, F.

10.1101/2020.02.04.930677 — genetics — Posted on 2020-02-04

3427 A Hierarchical Approach Using Marginal Summary Statistics for Multiple Intermediates in a Mendelian Randomization or Transcriptome Analysis

Jiang, L.; Xu, S.; Mancuso, N.; Newcombe, P. J.; Conti, D. V.

10.1101/2020.02.03.924241 — genetics — Posted on 2020-02-04

3428 High MHC gene copy number maintains diversity despite homozygosity in a Critically Endangered single-island endemic bird, but no evidence of MHC-based mate choice

Stervander, M.; Dierickx, E. G.; Thorley, J.; Brooke, M. d. L.; Westerdahl, H.

10.1101/2020.02.03.932590 — evolutionary biology — Posted on 2020-02-04

3429 CRISPR-mediated biocontainment

Castanon, O.; Smith, C. J.; Khoshakhlagh, P.; Ferreira, R.; Guell, M.; Said, K.; Yildiz, R.; Dysart, M.; Wang, S.; Thompson, D.; Myllykallio, H.; Church, G. M.

10.1101/2020.02.03.922146 — synthetic biology — Posted on 2020-02-04

3430 Enhanced stress tolerance through reduction of G3BP and suppression of stress granules

Lee, A. K.; Klein, J.; Fon Tacer, K.; Lord, T.; Oatley, M. L.; Oatley, J. M.; Porter, S. N.; Pruett-Miller, S. M.; Tikhonova, E. B.; Karamyshev, A. L.; Yang, P.; Kim, H. J.; Taylor, J. P.; Potts, P. R.

10.1101/2020.02.03.925677 — cell biology — Posted on 2020-02-04

3431 Design for Fast Optogenetic Screen In Mammalian Cells For Next Gen Ca2+ Sensors

Thomas, M. A.; Martinka, S.; Hughes, T.

10.1101/2020.02.03.932426 — bioengineering — Posted on 2020-02-04

3432 Modulation of plant Acetyl CoA Synthetase activity by acetylation

Sofeo, N.; Leung, K.; Nikolau, B. J.

10.1101/2020.01.31.928937 — biochemistry — Posted on 2020-02-04

3433 Neuroligin dependence of social behaviour in C. elegans provides a model to investigate an autism associated gene

Rawsthorne, H.; Calahorro, F.; Feist, E.; Holden-Dye, L.; O'Connor, V.; Dillon, J.

10.1101/2020.02.03.931592 — neuroscience — Posted on 2020-02-04

3434 Differentiating Drosophila female germ cells initiate Polycomb silencing by altering PRC2 sampling

DeLuca, S. Z.; Ghildiyal, M.; Niu, W.; Pang, L.-Y.; Spradling, A. C.

10.1101/2020.02.03.932582 — developmental biology — Posted on 2020-02-04

3435 Regulation of peroxisome and lipid droplet hitchhiking by PxdA and the DipA phosphatase

Salogiannis, J.; Christensen, J. R.; Aguilar-Maldonado, A.; Shukla, N.; Reck-Peterson, S. L.

10.1101/2020.02.03.932616 — cell biology — Posted on 2020-02-04

3436 The properties of buried ion pairs are governed by the propensity of proteins to reorganize

Kougentakis, C. M.; Skerritt, L.; Majumdar, A.; Schlessman, J. L.; Garcia-Moreno E., B.

10.1101/2020.02.03.932012 — biophysics — Posted on 2020-02-04

3437 An unusual MHC molecule generates protective CD8+ T cell responses to chronic infection

Tsitsiklis, A.; Bangs, D. J.; Lutes, L. L.; Chan, S.-W.; Geiger, K.; Modzelewski, A. J.; Labarta-Bajo, L.; Zuniga, E. I.; Robey, E. A.

10.1101/2020.02.03.932848 — immunology — Posted on 2020-02-04

3438 Lysophosphatidic acid-mediated GPR35 signaling in CX3CR1+ macrophages regulates the intestinal cytokine milieu

Kaya, B.; Donas Cuadra, C.; Wuggenig, P.; Diaz, O. E.; Morales, R. A.; Melhem, H.; Swiss IBD Cohort Investigators, ; Hernandez, P. P.; Kaymak, T.; Das, S.; Hruz, P.; Ayata, K.; Villablanca, E. J.; Niess, J. H.

10.1101/2020.02.03.932186 — immunology — Posted on 2020-02-04

3439 Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function

10.1101/2020.02.03.926949 — immunology — Posted on 2020-02-04

3440 The Subsystem Mechanism of Default Mode Network Underlying Rumination: a Reproducible Neuroimaging Study

Chen, X.; Chen, N.-X.; Shen, Y.-Q.; Li, H.-X.; Li, L.; Lu, B.; Zhu, Z.-C.; Fan, Z.; Yan, C.-G.

10.1101/841239 — neuroscience — Posted on 2020-02-04

3441 Optimal anticipatory control as a theory of movement preparation: a thalamo-cortical circuit model

Kao, T.-C.; Sadabadi, M. S.; Hennequin, G.

10.1101/2020.02.02.931246 — neuroscience — Posted on 2020-02-04

3442 Cellular identity and Ca2+ signaling activity of the non-reproductive GnRH system in the Ciona larva

Okawa, N.; Shimai, K.; Ohnishi, K.; Ohkura, M.; Nakai, J.; Horie, T.; Kuhara, A.; Kusakabe, T. G.

10.1101/2020.01.02.893354 — neuroscience — Posted on 2020-02-04

3443 ShearFAST: a user-friendly in vitro toolset for high throughput, inexpensive fluid shear stress experiments.

Smith, T. B.; De Nunzio, A. M.; Patel, K.; Munford, H.; Alam, T.; Powell, O.; Heneghan, N.; Ready, A.; Nath, J.; Ludwig, C.

10.1101/2020.01.31.929513 — cell biology — Posted on 2020-02-04

3444 Core-2 O-glycans are required for Galectin-3 interaction with the osteoarthritis related protein lubricin

Flowers, S. A.; Thomsson, K. A.; Ali, L.; Huang, S.; Mthembu, Y.; Regmi, S. C.; Holgersson, J.; Schimdt, T. A.; Rolfson, O.; Bjorkman, L. I.; Sundqvist, M.; Karlsson, A.; Jay, G. D.; Eisler, T.; Krawetz, R.; Karlsson, N. G.

10.1101/2019.12.20.884148 — biochemistry — Posted on 2020-02-04

3445 TOR coordinates nucleotide availability with ribosome biogenesis in plants

Busche, M.; Scarpin, M. R.; Hnasko, R.; Brunkard, J. O.

10.1101/2020.01.30.927418 — plant biology — Posted on 2020-02-04

3446 Prefrontal state fluctuations control access to consciousness

Dwarakanath, A.; Kapoor, V.; Werner, J.; Safavi, S.; Fedorov, L.; Logothetis, N. K.; Panagiotaropoulos, T. I.

10.1101/2020.01.29.924928 — neuroscience — Posted on 2020-02-04

3447 Disentangling Decision-related Feedforward and Feedback Signals in Human Cortex

Wilming, N.; Murphy, P. R.; Meyniel, F.; Donner, T.

10.1101/2020.02.01.929893 — neuroscience — Posted on 2020-02-04

3448 Nanopore adaptive sequencing for mixed samples, whole exome capture and targeted panels.

Payne, A.; Holmes, N.; Clarke, T.; Munro, R.; Debebe, B.; Loose, M. W.

10.1101/2020.02.03.926956 — genomics — Posted on 2020-02-04

3449 Fast assessment of human receptor-binding capability of 2019 novel coronavirus (2019-nCoV)

Huang, Q.; Herrmann, A.

10.1101/2020.02.01.930537 — genomics — Posted on 2020-02-04

3450 Change of information content due to natural selection in populations with and without recombination

Tiefenbrunner, W.

10.1101/2020.01.23.917724 — evolutionary biology — Posted on 2020-02-04

3451 Unifying single-cell annotations based on the Cell Ontology

Wang, S.; Pisco, A. O.; McGeever, A.; Brbic, M.; Zitnik, M.; Darmanis, S.; Leskovec, J.; Karkanias, J.; Altman, R. B.

10.1101/810234 — bioinformatics — Posted on 2020-02-04

3452 White matter microstructure predicts focal and broad functional brain dedifferentiation in normal aging

Rieck, J. R.; Rodrigue, K. M.; Park, D. C.; Kennedy, K. M.

10.1101/779264 — neuroscience — Posted on 2020-02-04

3453 Removal of Scanner Effects in Covariance Improves Multivariate Pattern Analysis in Neuroimaging Data

Chen, A. A.; Beer, J. C.; Tustison, N. J.; Cook, P. A.; Shinohara, R. T.; Shou, H.

10.1101/858415 — neuroscience — Posted on 2020-02-04

3454 Nanoscale Chromatin Imaging and Analysis (nano-ChIA) platform bridges 4-D chromatin organization with molecular function

LI, Y.; Eshein, A.; Virk, R.; Eid, A.; Wu, W.; Frederick, J.; VanDerway, D.; Gladstein, S.; Huang, K.; Anthony, N.; Bauer, G.; Zhou, X.; Agrawal, V.; Pujadas, E. M.; Chandler, J.; Nguyen, T.-Q.; Bleher, R.; de Pablo, J.; Szleifer, I.; Dravid, V. P.; Almassalha, L. M.; Backman, V.

10.1101/2020.01.26.920363 — genomics — Posted on 2020-02-04

3455 The genetic structure and adaptation of Andean highlanders and Amazonian dwellers is influenced by the interplay between geography and culture

Borda, V.; Alvim, I.; Aquino, M. M.; Silva, C.; Soares-Souza, G. B.; Leal, T. P.; Scliar, M. O.; Zamudio, R.; Zolini, C.; Padilla, C.; Caceres, O.; Levano, K.; Sanchez, C.; Trujillo, O.; Flores-Villanueva, P.; Dean, M.; Fuselli, S.; Machado, M.; Romero, P. E.; Tassi, F.; Yeager, M.; O'Connor, T. D.; Gilman, R. H.; Tarazona-Santos, E.; Guio, H.

10.1101/2020.01.30.916270 — evolutionary biology — Posted on 2020-02-04

3456 Phylogenomic resolution of sea spider diversification through integration of multiple data classes

Ballesteros, J. A.; Setton, E. V.; Santibanez-Lopez, C. E.; Arango, C. P.; Brenneis, G.; Brix, S.; Cano-Sanchez, E.; Dandouch, M.; Dilly, G. F.; Eleaume, M.; Gainett, G.; Gallut, C.; McAtee, S.; McIntyre, L.; Moran, A. L.; Moran, R.; Lopez-Gonzalez, P. J.; Scholtz, G.; Williamson, C.; Woods, H. A.; Wheeler, W. C.; Sharma, P. P.

10.1101/2020.01.31.929612 — evolutionary biology — Posted on 2020-02-04

3457 Unraveling nanotopography of cell surface receptors

Franke, C.; Chum, T.; Kvicalova, Z.; Glatzova, D.; Rodriguez, A.; Helmerich, D.; Frank, O.; Brdicka, T.; van de Linde, S.; Cebecauer, M.

10.1101/2019.12.23.884460 — cell biology — Posted on 2020-02-04

3458 iPSC-Derived Ovarian Tissue Restores Ovarian Function in Subfertile Mice and After Gonadotoxic Chemotherapy

Elias, K. M.; Ng, N. W.; Dam, K. U.; Milne, A. B.; Disler, E. R.; Gockley, A.; Holub, N.; Church, G. M.; Ginsburg, E. S.; Anchan, R. M.

10.1101/697532 — cell biology — Posted on 2020-02-04

3459 Simplitigs as an efficient and scalable representation of de Bruijn graphs

Brinda, K.; Baym, M.; Kucherov, G.

10.1101/2020.01.12.903443 — bioinformatics — Posted on 2020-02-04

3460 JEDI: Circular RNA Prediction based on Junction Encoders and Deep Interaction among Splice Sites

Jiang, J.-Y.; Ju, C. J.-T.; Hao, J.; Chen, M.; Wang, W.

10.1101/2020.02.03.932038 — bioinformatics — Posted on 2020-02-04

3461 Humans adapt their anticipatory eye movements to the volatility of visual motion properties

Pasturel, C.; Montagnini, A.; Perrinet, L. U.

10.1101/784116 — neuroscience — Posted on 2020-02-04

3462 SNP-based quantitative deconvolution of biological mixtures: application to the detection of cows with subclinical mastitis by whole genome sequencing of tank milk.

Coppieters, W.; Karim, L.; Georges, M.

10.1101/740894 — genomics — Posted on 2020-02-04

3463 A user's guide to the online resources for data exploration, visualization, and discovery for the Pan-Cancer Analysis of Whole Genomes project (PCAWG)

Goldman, M.; Zhang, J.; Fonseca, N. A.; Cortes-Ciriano, I.; Xiang, Q.; Craft, B.; Pineiro-Yanez, E.; O'Connor, B.; Bazant, W.; Barrera, E.; Munoz, A.; Petryszak, R.; Füllgrabe, A.; Al-Shahrour, F.; Keays, M.; Haussler, D.; Weinstein, J.; Huber, W.; Valencia, A.; Park, P. J.; Papatheodorou, I.; Zhu, J.; Ferreti, V.; Vazquez, M.; PCAWG Portals and Visualization Working Group, ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network,

10.1101/163907 — bioinformatics — Posted on 2020-02-04

3464 Oncoprotein 18 is necessary for malignant cell proliferation in bladder cancer cells and serves as a G3-specific non-invasive diagnostic marker candidate in urinary RNA

Hanke, M.; Dubois, J.; Kausch, I.; Petkovic, S.; Sczakiel, G.

10.1101/2020.02.03.932947 — cancer biology — Posted on 2020-02-03

3465 Behavioural cue reactivity to alcohol and non-alcohol-related stimuli among individuals with severe alcohol use disorder: an fMRI study with a visual task

Fukushima, S.; Kuga, H.; Oribe, N.; Mutou, T.; Yuzuriha, T.; Ozawa, H.; Ueno, T.

10.1101/2020.02.03.932889 — neuroscience — Posted on 2020-02-03

3466 Development and validation of the Irish Science Self-Efficacy Children's Questionnaire to assess the short-term influence of scientists facilitating outreach

Carroll, S.; Sheahan, J.; McCauley, V.; Grenon, M.

10.1101/2020.01.25.919357 — scientific communication and education — Posted on 2020-02-03

3467 Divided attention for feature-based selection in visual cortex

Moreland, J. C.; Boynton, G. M.

10.1101/2020.01.27.922047 — neuroscience — Posted on 2020-02-03

3468 Perinatal THC Exposure via Lactation Induces Lasting Alterations to Social Behavior and Prefrontal Cortex Function in Rats at Adulthood

Scheyer, A. F.; Borsoi, M.; Manzoni, O. J.

10.1101/2020.02.03.931733 — neuroscience — Posted on 2020-02-03

3469 The R2R3-MYB gene family in banana (Musa acuminata): genome-wide identification, classification and expression patterns

Pucker, B.; Pandey, A.; Weisshaar, B.; Stracke, R.

10.1101/2020.02.03.932046 — plant biology — Posted on 2020-02-03

3470 QTG-Finder2: a generalized machine-learning algorithm for prioritizing QTL causal genes in plants

Lin, F.; Lazarus, E. Z.; Rhee, S. Y.

10.1101/2020.02.03.931444 — bioinformatics — Posted on 2020-02-03

3471 Energy supply per neuron is constrained by capillary density in the mouse brain

Ventura-Antunes, L.; Herculano-Houzel, S.

10.1101/2020.02.03.932434 — neuroscience — Posted on 2020-02-03

3472 Omnidirectional and omnifunctional connectivity analyses with a diverse species pool

Lecours-Tessier, D.; Maranger, R.; Poisot, T.

10.1101/2020.02.03.932095 — ecology — Posted on 2020-02-03

3473 Estimating maximum sustainable yield of snow crab (Chionoecetes opilio) off Tohoku Japan via a state-space assessment model with time-varying natural mortality

Shibata, Y.; Nagao, J.; Narimatsu, Y.; Morikawa, E.; Suzuki, Y.; Tokioka, S.; Yamada, M.; Kakehi, S.; Okamura, H.

10.1101/2020.02.02.931428 — ecology — Posted on 2020-02-03

3474 Algorithm for Extraction of Sub-Structure from Co-Crystallized PDB Ligand for Selective Targeting

Prakash, O.

10.1101/2020.02.02.931436 — bioinformatics — Posted on 2020-02-03

George, E. A.; Pimplikar, S.; Thulasi, N.; Brockmann, A.

10.1101/2020.02.02.931345 — animal behavior and cognition — Posted on 2020-02-03

3476 Long-range Temporal Correlations in the Broadband Resting state Activity of the Human Brain revealed by Neuronal Avalanches

Lombardi, F.; Shriki, O.; Herrmann, H. J.; de Arcangelis, L.

10.1101/2020.02.03.930966 — neuroscience — Posted on 2020-02-03

3477 Decoding non-conscious thought representations during successful thought suppression

Koenig-Robert, R.; Pearson, J.

10.1101/2020.02.02.931352 — neuroscience — Posted on 2020-02-03

3478 cDNA library screening to identify interacting proteins of Golgi-localized type II membrane proteins

Lund, C. H.; Bromley, J. R.; Lopez-Marques, R. L.; Sakuragi, Y.

10.1101/2020.02.03.932111 — molecular biology — Posted on 2020-02-03

3479 Computational Investigation of Visually Guided Learningof Spatially Aligned Auditory Maps in the Colliculus

Oess, T.; Ernst, M. O.; Neumann, H.

10.1101/2020.02.03.931642 — neuroscience — Posted on 2020-02-03

3480 Feedback motifs tuned by microRNAs in human transcriptional networks

Minchington, T. G.; Griffiths-Jones, S.; Papalopulu, N.

10.1101/2020.02.03.932152 — bioinformatics — Posted on 2020-02-03

3481 Re-evaluating the conventional wisdom about binding assays

Wilson, B. D.; Soh, H. T.

10.1101/2020.02.03.932392 — bioengineering — Posted on 2020-02-03

3482 aNy-way Independent Component Analysis

Duan, K.; Silva, R. F.; Calhoun, V. D.; Liu, J.

10.1101/2020.02.03.930156 — bioengineering — Posted on 2020-02-03

3483 A mouse SWATH-MS reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

Krasny, L.; Bland, P.; Burns, J.; Lima, N. C.; Harrison, P. T.; Pacini, L.; Elms, M. L.; Ning, J.; Martinez, V. G.; Yu, Y.-R.; Acton, S. E.; Ho, P.-C.; Calvo, F.; Swain, A.; Howard, B. A.; Natrajan, R. C.; Huang, P. H.

10.1101/2020.02.03.930248 — biochemistry — Posted on 2020-02-03

3484 Identifiability and experimental design in perturbation studies

Gross, T.; Bluthgen, N.

10.1101/2020.02.03.931816 — systems biology — Posted on 2020-02-03

3485 A Guide to the Quantitative Proteomic Profiles of the Cancer Cell Line Encyclopedia

Nusinow, D. P.; Gygi, S. P.

10.1101/2020.02.03.932384 — systems biology — Posted on 2020-02-03

3486 New Tools for Hop Cytogenomics: Identification of Tandem Repeat Families from Long-Read Sequences of Humulus lupulus

Easterling, K. A.; Pitra, N. J.; Morcol, T. B.; Aquino, J. R.; Lopes, L. A.; Bussey, K. C.; Matthews, P. D.; Bass, H. W.

10.1101/2020.02.03.931790 — plant biology — Posted on 2020-02-03

3487 Conditional Lpar1 gene targeting identifies cell types mediating neuropathic pain

Rivera, R.; Lin, M.-E.; Bornhop, E. C.; Chun, J.

10.1101/2020.02.02.931212 — pharmacology and toxicology — Posted on 2020-02-03

3488 Stability of synchronous states in sparse neuronal networks

Afifurrahman, ; Ullner, E.; Politi, A.

10.1101/2020.02.02.931048 — neuroscience — Posted on 2020-02-03

3489 Individual differences in social reward and threat expectancies linked to grey matter volumes in key regions of the social brain

Crawford, B.; Muhlert, N.; MacDonald, G.; Lawrence, A. D.

10.1101/2020.02.03.916999 — neuroscience — Posted on 2020-02-03

3490 Rotational snapping: Illusory rhythmicity induced by global and local motion binding

Han, H.-B.

10.1101/2020.02.03.931758 — neuroscience — Posted on 2020-02-03

3491 Deficiency of complement component C1Q prevents cerebrovascular damage and white matter loss in a mouse model of chronic obesity

Graham, L.; Kocalis, H.; Soto, I.; Howell, G.

10.1101/2020.02.03.931949 — neuroscience — Posted on 2020-02-03

3492 Signal transfer of visual stimuli to V4 occurs in gamma-rhythmic, pulsed information packages

Lisitsyn, D.; Grothe, I.; Kreiter, A. K.; Ernst, U. A.

10.1101/2020.02.03.931956 — neuroscience — Posted on 2020-02-03

3493 Equivolumetric protocol generates library sizes proportional to total microbial load in next-generation sequencing

Netto Flores Cruz, G.; Christoff, A. P.; Valter de Oliveira, L. F.

10.1101/2020.02.03.932301 — molecular biology — Posted on 2020-02-03

3494 Persistent telomere cohesion protects aged cells from premature senescence

Azarm, K.; Bhardwaj, A.; Kim, E.; Smith, S.

10.1101/2020.02.03.932145 — molecular biology — Posted on 2020-02-03

3495 Microbial grazers can control chytridiomycosis caused by aquatic zoosporic fungi

Farthing, H. N.; Jiang, J.; Henwood, A. J.; Fenton, A.; Fisher, M. C.; Montagnes, D. J. S.

10.1101/2020.02.03.931857 — microbiology — Posted on 2020-02-03

3496 EslB is required for cell wall Integrity and cell division in Listeria monocytogenes

Rismondo, J.; Yacoub, M.; Wadhawan, A.; Dionne, M. S.; Gründling, A.

10.1101/2020.02.03.932061 — microbiology — Posted on 2020-02-03

3497 A lung-on-chip infection model reveals protective and permissive roles of alveolar epithelial cells in tuberculosis

Thacker, V. V.; Dhar, N.; Sharma, K.; Barrile, R.; Karalis, K.; McKinney, J. D.

10.1101/2020.02.03.931170 — microbiology — Posted on 2020-02-03

3498 Iterative transfer learning with neural network for clustering and cell type classification in single-cell RNA-seq analysis

Hu, J.; Li, X.; Hu, G.; Lyu, Y.; Susztak, K.; Li, M.

10.1101/2020.02.02.931139 — genomics — Posted on 2020-02-03

3499 Epigenome-based Splicing Prediction using a Recurrent Neural Network

Lee, D.; Zhang, J.; Liu, J.; Gerstein, M.

10.1101/2020.02.03.932251 — genomics — Posted on 2020-02-03

3500 Giant African snail genomes provide insights into molluscan whole-genome duplication and aquatic-terrestrial transition

Liu, C.; Ren, Y.; Li, Z.; Hu, Q.; Yin, L.; Qiao, X.; Zhang, Y.; Xing, L.; Xi, Y.; Jiang, F.; Wang, S.; Huang, C.; Liu, B.; Wang, H.; Liu, H.; Wan, F.; Qian, W.; Fan, W.

10.1101/2020.02.02.930693 — genomics — Posted on 2020-02-03

3501 The Oft-Overlooked Massively Parallel Reporter Assay: Where, When, and Which Psychiatric Genetic Variants are Functional?

Mulvey, B.; Lagunas, T.; Dougherty, J. D.

10.1101/2020.02.02.931337 — genetics — Posted on 2020-02-03

3502 Mining Whole Genome Sequence data to efficiently attribute individuals to source populations

Perez-Reche, F.; Rotariu, O.; Lopes, B.; Strachan, N. J.; Forbes, K. J.

10.1101/2020.02.03.932343 — evolutionary biology — Posted on 2020-02-03

3503 Electrostatic effects in proteins are governed by pH-redistribution of the conformational ensemble

Kougentakis, C. M.; Majumdar, A.; Garcia-Moreno E., B.

10.1101/2020.02.02.931253 — biophysics — Posted on 2020-02-03

3504 Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires Bicc1-Ccr4 RNA degradation complex

Minegishi, K.; Rothe, B.; Komatsu, K. R.; Ono, H.; Ikawa, Y.; Nishimura, H.; Miyashita, E.; Takaoka, K.; Bando, K.; Kiyonari, H.; Yamamoto, T.; Saito, H.; Constam, D. B.; Hamada, H.

10.1101/2020.02.02.931477 — developmental biology — Posted on 2020-02-03

3505 Continual inactivation of stem cell functional identity genes stabilizes progenitor commitment

Quinto-Rives, N.; Komori, H.; Janssens, D. H.; Kondo, S.; Dai, Q.; Moore, A. W.; Lee, C.-Y.

10.1101/2020.02.03.931972 — developmental biology — Posted on 2020-02-03

3506 Fast assessment of human receptor-binding capability of 2019 novel coronavirus (2019-nCoV)

Huang, Q.; Herrmann, A.

10.1101/2020.02.01.930537 — genomics — Posted on 2020-02-03

3507 Designing an occupancy framework to monitor an endemic rainforest duck: Methodological and modelling considerations

Jelil, S. N.; Parasar, M.; Cancino, L.; Cook, K.

10.1101/2020.02.03.931543 — ecology — Posted on 2020-02-03

3508 Tumor susceptibility gene-101 regulates glucocorticoid receptor through disorder-mediated allostery

White, J. T.; Rives, J.; Tharp, M. E.; Wrabl, J. O.; Thompson, E. B.; Hilser, V. J.

10.1101/2020.02.02.931485 — biophysics — Posted on 2020-02-03

3509 A Micro-Engineered Airway Lung-Chip Models Key Features of Viral-Induced Exacerbation of Asthma

Nawroth, J. C.; Lucchesi, C.; Cheng, D.; Shukla, A.; Nguyen, J.; Shroff, T.; Karalis, K.; Lee, H.-H.; Alves, S.; Hamilton, G.; Salmon, M.; Villenave, R.

10.1101/2020.02.02.931055 — bioengineering — Posted on 2020-02-03

3510 The usefulness of multi-parent multi-environment QTL analysis: an illustration in different NAM populations

Garin, V.; Malosetti, M.; van Eeuwijk, F.

10.1101/2020.02.03.931626 — genetics — Posted on 2020-02-03

3511 New Lipophilic Fluorescent Dyes for Exosome Labeling: Monitoring of Cellular Uptake of Exosomes

Shimomura, T.; Seino, R.; Umezaki, K.; Shimoda, A.; Ezoe, T.; Ishiyama, M.; Akiyoshi, K.

10.1101/2020.02.02.931295 — biochemistry — Posted on 2020-02-03

3512 Plastid EF-Tu Regulates Root Development through Both the ATM Pathway and GUN1

Li, P.; Ma, J.; Sun, X.; Zhao, C.-Z.; Ma, C.; Wang, X.-J.

10.1101/2020.02.03.932574 — plant biology — Posted on 2020-02-03

3513 Detecting strawberry cultivar misidentification in the Philippines using single nucleotide polymorphism markers from the anthocyanin reductase gene

Ledesma, N. A.; Matulac, J. M.; Sevilleja, J. E.; Enriquez, M. L.

10.1101/2020.02.02.922369 — molecular biology — Posted on 2020-02-03

3514 A double role of the Gal80 N-terminus in activation of transcription by Gal4p

Reinhardt-Tews, A.; Krutyholova, R.; Guenzel, C.; Glatt, S.; Breunig, K. D.

10.1101/2020.02.03.931568 — molecular biology — Posted on 2020-02-03

3515 Hybridization-based In Situ Sequencing (HybISS): spatial transcriptomic detection in human and mouse brain tissue

Gyllborg, D.; Mattsson Langseth, C.; Qian, X.; Marco Salas, S.; Hilscher, M. M.; Lein, E. S.; Nilsson, M.

10.1101/2020.02.03.931618 — molecular biology — Posted on 2020-02-03

3516 Dynamics of mcr-1 prevalence and mcr-1-positive Escherichia coli after the cessation of colistin use as a feed additive for animals in China: a prospective cross-sectional and whole genome sequencing based molecular epidemiological study

Shen, C.; Zhong, L.-L.; Yang, Y.; Doi, Y.; Paterson, D. L.; Stoesser, N.; Ma, F.; Ahmed, M. A. E.-G. E.-S.; Feng, S.; Huang, S.; Li, H.-Y.; Huang, X.; Wen, X.; Zhao, Z.; Lin, M.; Chen, G.; Liang, W.; Liang, Y.; Xia, Y.; Dai, M.; Chen, D.-Q.; Zhang, L.; Liao, K.; Tian, G.-B.

10.1101/2020.02.03.923607 — microbiology — Posted on 2020-02-03

3517 RAS activation via CRLF2 signaling is a widespread mechanism in Down syndrome acute lymphoblastic leukemia regardless of RAS mutations

Koschut, D.; Ray, D.; Li, Z.; Giarin, E.; Groet, J.; Alic, I.; Kham, S. K.-Y.; Chng, W.-J.; Ariffin, H.; Weinstock, D. M.; Yeoh, A. E.-J.; Basso, G.; Nizetic, D.

10.1101/2020.02.03.931725 — cancer biology — Posted on 2020-02-03

3518 MLQ is responsible for stabilisation of subunit a in the holoenzyme of mammalian ATP synthase

Tauchmannova, K.; Ho, H. D.; Nuskova, H.; Pecinova, A.; Alan, L.; Rodinova, M.; Konarikova, E.; Vrbacky, M.; Puertas, G.; Kaplanova, V.; Houstek, J.; Pecina, P.; Mracek, T.

10.1101/2020.02.03.931709 — biochemistry — Posted on 2020-02-03

3519 Gene loss and acquisition in lineages of bacteria evolving in a human host environment

Gabrielaite, M.; Johansen, H. K.; Molin, S.; Nielsen, F. C.; Marvig, R. L.

10.1101/2020.02.03.931667 — evolutionary biology — Posted on 2020-02-03

3520 Fast transport of RNA granules by direct interactions with KIF5A/KLC1 motors prevents axon degeneration

Segal, R. A.; Seo, H.-S.; Adelmant, G.; Walensky, L.; Marto, J. A.; Dhe-Paganon, S.; Fukuda, Y.; Pazyra-Murphy, M. F.; Tasdemir-Yilmaz, O. E.; Li, Y.; Rose, L.; Yeoh, Z. C.; Vangos, N. E.; Geffken, E. A.; Bird, G. H.

10.1101/2020.02.02.931204 — cell biology — Posted on 2020-02-03

3521 Metabolic pathway inference using multi-label classification with rich pathway features

Mohd Abul Basher, A. R.; McLaughlin, R.; Hallam, S.

10.1101/2020.02.02.919944 — bioinformatics — Posted on 2020-02-03

3522 A single-cell RNAseq atlas of the pathogenic stage of Schistosoma mansoni identifies a key regulator of blood feeding

Wendt, G.; Zhao, L.; Chen, R.; Lu, C.; O'Donoghue, A. J.; Caffrey, C. R.; Collins, J.

10.1101/2020.02.03.932004 — microbiology — Posted on 2020-02-03

3523 Calibrated rare variant genetic risk scores for complex disease prediction using large exome sequence repositories

Lali, R.; Chong, M.; Omidi, A.; Mohammadi-Shemirani, P.; Le, A.; Pare, G.

10.1101/2020.02.03.931519 — genetics — Posted on 2020-02-03

3524 UFMylation regulates translational homeostasis and cell cycle progression

Gak, I. A.; Vasiljevic, D.; Zerjatke, T.; Yu, L.; Brosch, M.; Roumeliotis, T. I.; Horenburg, C.; Klemm, N.; Bakos, G.; Herrmann, A.; Hampe, J.; Glauche, I.; Choudhary, J. S.; Mansfeld, J.

10.1101/2020.02.03.931196 — cell biology — Posted on 2020-02-03

3525 DPHL: A pan-human protein mass spectrometry library for robust biomarker discovery using Data-Independent Acquisition and Parallel Reaction Monitoring

Zhu, T.; Zhu, Y. J.; Xuan, Y.; Gao, H.; Cai, X.; Piersma, S. R.; Pham, T. V.; Schelfhorst, T.; de Haas, R. R.; Bijnsdorp, I. V.; Sun, R.; Yue, L.; Ruan, G.; Zhang, Q.; Hu, M.; Zhou, Y.; Houdt, W. J. V.; Le Large, T. Y.; Cloos, J.; Wojtuszkiewicz, A.; Koppers-Lalic, D.; Bottger, F.; Scheepbouwer, C.; Brakenhoff, R. H.; Leenders, G. J. L. H. v.; Ijzermans, J. N. M.; Martens, J. W. M.; Steenbergen, R. D. M.; Grieken, N. C.; Selvarajan, S.; Mantoo, S.; Lee, S. S.; Yeow, S. J. Y.; Alkaff, S. M. F.; Nan, X.; Sun, Y.; Yi, X.; Dai, S.; Liu, W.; Lu, T.; Wu, Z.; Liang, X.; Wang, M.; Shao, Y.; Zheng, X.;

10.1101/2020.02.03.931329 — bioinformatics — Posted on 2020-02-03

3526 Unsupervised Topological Alignment for Single-Cell Multi-Omics Integration

Cao, K.; Bai, X.; Hong, Y.; Wan, L.

10.1101/2020.02.02.931394 — bioinformatics — Posted on 2020-02-03

3527 Cellpose: a generalist algorithm for cellular segmentation

Stringer, C.; Michaelos, M.; Pachitariu, M.

10.1101/2020.02.02.931238 — bioinformatics — Posted on 2020-02-03

3528 JEDI: Circular RNA Prediction based on Junction Encoders and Deep Interaction among Splice Sites

Jiang, J.-Y.; Ju, C. J.-T.; Hao, J.; Chen, M.; Wang, W.

10.1101/2020.02.03.932038 — bioinformatics — Posted on 2020-02-03

3529 Direct reprogramming of astrocytes to neurons leads to functional recovery after stroke

Livingston, J.; Lee, T.; Daniele, E.; Phillips, C.; Krassikova, A.; Enbar, T.; Kortebi, I.; Bang, K. W. A.; Donville, B.; Ibragimov, O.; Sachewsky, N.; Morshead, C.; Faiz, M.

10.1101/2020.02.02.929091 — neuroscience — Posted on 2020-02-03

3530 Cell competition regulates the kinetics of thymopoiesis and thymus cellularity

Ramos, C. V.; Ballesteros-Arias, L.; Silva, J. G.; Nogueira, M.; Gjini, E.; Martins, V. C.

10.1101/2019.12.21.885673 — immunology — Posted on 2020-02-03

3531 Argonaute catalytic activity is required for maternal mRNA clearance in embryos

Quarato, P.; Singh, M.; Cornes, E.; Li, B.; Bourdon, L.; Cecere, G.

10.1101/2020.02.03.919597 — developmental biology — Posted on 2020-02-03

3532 Proteome Exploration of Legionella pneumophila for Identifying Novel Therapuetics: A Hierarchical Subtractive Genomics and Reverse Vaccinology Approach

Khan, M. T.; Mahmud, A.; Hasan, M.; Azim, K. F.; Begum, M. K.; Akter, A.; Mondal, S. I.

10.1101/2020.02.03.922864 — bioinformatics — Posted on 2020-02-03

3533 Categorizing SHR and WKY rats by chi2 algorithm and decision tree

Tsai, P.-R.; Chen, K.-H.; Hong, T.-M.; Wang, F.-N.; Huang, T.-Y.

10.1101/2020.02.03.931899 — bioinformatics — Posted on 2020-02-03

3534 SCSIM: Jointly simulating correlated single-cell and bulk next-generation DNA sequencing data

Giguere, C.; Dubey, H. V.; Sarsani, V. K.; Saddiki, H.; He, S.; Flaherty, P.

10.1101/2020.02.03.930354 — bioinformatics — Posted on 2020-02-03

3535 Potent neutralization of 2019 novel coronavirus by recombinant ACE2-Ig

Lei, C.; Fu, W.; Qian, K.; Li, T.; Zhang, S.; Ding, M.; Hu, S.

10.1101/2020.02.01.929976 — bioengineering — Posted on 2020-02-03

3536 Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA

Walden, H.; Rennie, M. L.; Lemonidis, K.; Arkinson, C.; Chaugule, V. K.; Clarke, M.; Streetley, J.; Spagnolo, L.

10.1101/2020.02.03.931576 — biochemistry — Posted on 2020-02-03

3537 Imaging mass spectrometry and shotgun proteomics reveal dysregulated pathways in male infertility

Lahiri, S.; Valenta, L.; Aftab, W.; Strauss, L.; Poutanen, M.; Mayerhofer, A.; Imhof, A.

10.1101/2020.02.03.931931 — biochemistry — Posted on 2020-02-03

3538 Distinct and shared contributions of diagnosis and symptom domains to cognitive performance in a case-control study of severe mental illness in the Paisa population

Service, S. K.; Vargas Upegui, C.; Castano Ramirez, M.; Port, A.; Moore, T.; Munoz Umanes, M.; Agudelo Arango, L. G.; Diaz-Zuluaga, A. M.; Melo Esepjo, J.; Lopez, M. C.; Palacio, J. D.; Sanchez Ruiz, S.; Valencia, J.; Teshiba, T.; Espinoza, A.; Olde Loohuis, L.; De la Hoz Gomez, J.; Brodey, B.; Sabatti, C.; Escobar, J. I.; Reus, V. I.; Lopez Jaramillo, C.; Gur, R.; Bearden, C. E.; Freimer, N. B.

10.1101/731265 — neuroscience — Posted on 2020-02-03

3539 Anticipatory control of movement in a thalamo-cortical circuit model

Kao, T.-C.; Sadabadi, M. S.; Hennequin, G.

10.1101/2020.02.02.931246 — neuroscience — Posted on 2020-02-03

3540 DOT1L Methyltransferase Activity Preserves SOX2-Enhancer Accessibility And Prevents Activation of Repressed Genes In Murine Stem Cells

Ferrari, F.; Arrigoni, L.; Franz, H.; Butenko, L.; Trompouki, E.; Vogel, T.; Manke, T.

10.1101/2020.02.03.931741 — genomics — Posted on 2020-02-03

3541 Spatial-temporal dynamics of a microbial cooperative behavior robust to cheating

Monaco, H.; Sereno, T.; Liu, K.; Reagor, C.; Deforet, M.; Xavier, J.

10.1101/2020.01.23.914481 — evolutionary biology — Posted on 2020-02-03

3542 Phylogenomics of monitor lizards and the role of competition in dictating body size disparity

Brennan, I. G.; Lemmon, A. R.; Moriarty Lemmon, E.; Portik, D. M.; Weijola, V.; Welton, L.; Donnellan, S. C.; Keogh, J. S.

10.1101/2020.02.02.931188 — evolutionary biology — Posted on 2020-02-03

3543 Zebrafish Kit ligands cooperate with erythropoietin to promote erythroid cell expansion

Oltova, J.; Svoboda, O.; Svatonova, P.; Kolar, M.; Bartunek, P.

10.1101/2020.02.03.931634 — developmental biology — Posted on 2020-02-03

3544 MaTAR25 LncRNA Regulates the Tensin1 Gene to Impact Breast Cancer Progression

Chang, K.-C.; Diermeier, S. D.; Yu, A. T.; Brine, L. D.; Russo, S.; Bhatia, S.; Alsudani, H.; Kostroff, K.; Bhuiya, T.; Brogi, E.; Bennett, C. F.; Rigo, F.; Spector, D. L.

10.1101/2020.02.03.931881 — cancer biology — Posted on 2020-02-03

3545 Small Cell Lung Cancer Neuroendocrine Subtypes are Associated with Different Immune Microenvironment and Checkpoint Molecule Distribution

Dora, D.; Rivard, C.; Yu, H.; Bunn, P.; Suda, K.; Ren, S.; Pickard, S. L.; Laszlo, V.; Harko, T.; Megyesfalvi, Z.; Moldvay, J.; Hirsch, F. R.; Dome, B.; Lohinai, Z.

10.1101/2020.02.02.930305 — cancer biology — Posted on 2020-02-03

3546 A post-processing algorithm for building longitudinal medication dose data from extracted medication information using natural language processing from electronic health records

McNeer, E.; Beck, C.; Weeks, H. L.; Williams, M. L.; James, N. T.; Choi, L.

10.1101/775015 — bioinformatics — Posted on 2020-02-03

3547 Candidate gene prioritization using graph embedding

DO, Q.; LARMANDE, P.

10.1101/2020.02.03.927913 — bioinformatics — Posted on 2020-02-03

3548 Build a Better Bootstrap and the RAWR Shall Beat a Random Path to Your Door: Phylogenetic Support Estimation Revisited

Wang, W.; Liu, K. J.

10.1101/2020.02.02.931063 — bioinformatics — Posted on 2020-02-03

3549 Characterising open chromatin identifies novel cis-regulatory elements important for paraxial mesoderm formation and axis extension

Mok, G. F.; Folkes, L.; Weldon, S.; Maniou, E.; Martinez-Heredia, V.; Godden, A.; Williams, R.; Wheeler, G. N.; Moxon, S.; Munsterberg, A.

10.1101/2020.01.20.912337 — developmental biology — Posted on 2020-02-03

3550 Short paired-end reads trump long single-end reads for expression analysis

Freedman, A. H.; Gaspar, J. M.; Sackton, T. B.

10.1101/777409 — bioinformatics — Posted on 2020-02-03

3551 TRACE: An unbiased method to permanently tag transiently activated inputs

Krauth, N.; Khalil, V.; Jariwala, M.; Mermet-Joret, N.; Vestergaard, A.-K.; Capogna, M.; Nabavi, S.

10.1101/2020.02.02.927194 — neuroscience — Posted on 2020-02-03

3552 Feedback control of a two-component signaling system by an Fe-S-binding receiver domain

Stein, B. J.; Fiebig, A.; Crosson, S.

10.1101/729053 — microbiology — Posted on 2020-02-03

3553 DNA breaks-mediated cost reveals RNase HI as a new target for selectively eliminating antibiotic resistance

Balbontin, R.; Frazao, N.; Gordo, I.

10.1101/756767 — microbiology — Posted on 2020-02-03

3554 Epistasis, inbreeding depression and the evolution of self-fertilization

Abu Awad, D.; Roze, D.

10.1101/809814 — evolutionary biology — Posted on 2020-02-03

3555 High throughput identification of miR-145 targets in human articular chondrocytes

Martinez-sanchez, A.; Sharma, E.; Lazzarano, S.; Murphy, C.

10.1101/2020.02.03.931683 — cell biology — Posted on 2020-02-03

3556 Endogenous retroviruses drive KRAB zinc-finger family protein expression for tumor suppression

Ito, J.; Kimura, I.; Soper, A.; Coudray, A.; Koyanagi, Y.; Nakaoka, H.; Inoue, I.; Turelli, P.; Trono, D.; Sato, K.

10.1101/2020.02.02.931501 — cancer biology — Posted on 2020-02-03

3557 Single-particle view of stress-promoters induction dynamics: an interplay between MAPK signaling, chromatin and transcription factors

Wosika, V.; Pelet, S.

10.1101/728329 — biochemistry — Posted on 2020-02-03

3558 Healthy ageing and sentence production: Disrupted lexical access in the context of intact syntactic planning

Hardy, S. M.; Segaert, K.; Wheeldon, L.

10.1101/327304 — neuroscience — Posted on 2020-02-03

3559 Automated characterization of noise distributions in diffusion MRI data

St-Jean, S.; De Luca, A.; Tax, C. M. W.; Viergever, M. A.; Leemans, A.

10.1101/686436 — neuroscience — Posted on 2020-02-03

3560 On the mechanistic roots of an ecological law: parasite aggregation

Rabajante, J. F.; Anzia, E. L.; Gokhale, C. S.

10.1101/680041 — ecology — Posted on 2020-02-03

3561 Evolution and genetic architecture of disassortative mating at a locus under heterozygote advantage

Maisonneuve, L.; Joron, M.; Chouteau, M.; Llaurens, V.

10.1101/616409 — evolutionary biology — Posted on 2020-02-03

3562 SoupX removes ambient RNA contamination from droplet based single cell RNA sequencing data

Young, M. D.; Behjati, S.

10.1101/303727 — bioinformatics — Posted on 2020-02-03

3563 Dual acting small-Molecule inhibitors targeting Mycobacterial DNA replication

Singh, M.; Ilic, S.; Tam, B.; Ben-Ishay, Y.; Pappo, D.; Akabayov, B.

10.1101/561506 — biochemistry — Posted on 2020-02-03

3564 Finding recurrent RNA structural networks with fast maximal common subgraphs of edge-colored graphs

Soule, A.; Reinharz, V.; Sarrazin-Gendron, R.; Denise, A.; Waldispühl, J.

10.1101/2020.02.02.930453 — bioinformatics — Posted on 2020-02-03

3565 talklr uncovers ligand-receptor mediated intercellular crosstalk

Wang, Y.

10.1101/2020.02.01.930602 — bioinformatics — Posted on 2020-02-03

3566 Analysis of translating mitoribosome reveals functional characteristics of protein synthesis in mitochondria of fungi

Naschberger, A.; Itoh, Y.; Mortezaei, N.; Herrmann, J.; Amunts, A.

10.1101/2020.01.31.929331 — biochemistry — Posted on 2020-02-03

3567 Dynamic High-Content Imaging Reveals Surface Exposure Of Virulent Leishmania Amastigotes In Infected Macrophages Undergoing Pyroptosis

Rosazza, T.; Lecoeur, H.; Blisnick, T.; Moya-Nilges, M.; Pescher, P.; Bastin, P.; Prina, E.; Spaeth, G. F.

10.1101/2020.02.03.931907 — immunology — Posted on 2020-02-03

3568 Molecular Modeling Evaluation of the Binding Abilities of Ritonavir and Lopinavir to Wuhan Pneumonia Coronavirus Proteases

Lin, S.; Shen, R.; Guo, X.

10.1101/2020.01.31.929695 — biochemistry — Posted on 2020-02-03

3569 BiCoN: Network-constrained biclustering of patients and omics data

Lazareva, O.; Van Do, H.; Canzar, S.; Yuan, K.; Baumbach, J.; Tieri, P.; Kacprowski, T.; List, M.

10.1101/2020.01.31.926345 — bioinformatics — Posted on 2020-02-03

3570 A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer's disease

Gharahkhani, P.; Jorgenson, E.; Hysi, P.; Khawaja, A. P.; Pendergrass, S.; Han, X.; Ong, J. S.; Hewitt, A. W.; Segre, A.; Igo, R. P.; Choquet, H.; Qassim, A.; Josyula, N. S.; Cooke Bailey, J. N.; Bonnemaijer, P.; Iglesias, A.; Siggs, O. M.; Young, T.; Vitart, V.; Thiadens, A. A. H. J.; Karjalainen, J.; Uebe, S.; Melles, R. B.; Nair, S.; Luben, R.; Simcoe, M.; Amersinghe, N.; Cree, A. J.; Hohn, R.; Poplawski, A.; Chen, L. J.; Cheng, C.-Y.; Vithana, E. N.; NEIGHBORHOOD consortium, ; ANZRAG consortium, ; Biobank Japan project, ; FinnGen study, ; UK Biobank Eye and Vision Consortium, ; GIGA s

10.1101/2020.01.30.927822 — genetics — Posted on 2020-02-03

3571 Targeted nanopore sequencing by real-time mapping of raw electrical signal with UNCALLED

Kovaka, S.; Fan, Y.; Ni, B.; Timp, W.; Schatz, M. C.

10.1101/2020.02.03.931923 — genomics — Posted on 2020-02-03

3572 Nanopore adaptive sequencing for mixed samples, whole exome capture and targeted panels.

Payne, A.; Holmes, N.; Clarke, T.; Munro, R.; Debebe, B.; Loose, M. W.

10.1101/2020.02.03.926956 — genomics — Posted on 2020-02-03

3573 Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle fusion and replenishment in a dosage-dependent manner

Guan, Z.; Quinones-Frias, M. C.; Akbergenova, Y.; Littleton, J. T.

10.1101/2020.01.30.926246 — neuroscience — Posted on 2020-02-03

3574 Functional abnormalities in the cerebello-thalamic pathways in an animal model of dystonia

Margarint, E. L.; Baba Aissa, H.; Varani, A. P.; Sala, R.; Menardy, F.; Pelosi, A.; Herve, D.; Lena, C.; Popa, D.

10.1101/2020.01.29.926170 — neuroscience — Posted on 2020-02-03

3575 Hmx3a does not require its homeodomain for its essential functions in spinal cord, ear and lateral line development.

England, S. J.; Cerda, G. A.; Kowalchuk, A. M.; Sorice, T.; Grieb, G. M.; Lewis, K. E.

10.1101/2020.01.23.917468 — genetics — Posted on 2020-02-03

3576 Supplemented nutrition increases immunity and drug efficacy in a natural host-helminth system

Sweeny, A. R.; Clerc, M.; Pontifes, P. A.; Venkatesan, S.; Babayan, S. A.; Pedersen, A. B.

10.1101/837617 — ecology — Posted on 2020-02-03

3577 Artificial-Cell-Type Aware Cell Type Classification in CITE-seq

Lian, Q.; Xin, H.; Ma, J.; Konnikova, L.; Chen, W.; Gu, J.; Chen, K.

10.1101/2020.01.31.928010 — bioinformatics — Posted on 2020-02-03

3578 A mathematical model exhibiting the effect of DNA methylation on the stability boundary in cell-fate networks

Chen, T.; Ali Al-Radhawi, M.; Sontag, E.

10.1101/2019.12.19.883280 — systems biology — Posted on 2020-02-03

3579 Dopaminergic and opioidergic regulation of implicit hedonic facial reactions during anticipation and consumption of social and nonsocial rewards

Korb, S.; Goetzendorfer, S. J.; Massaccesi, C.; Sezen, P.; Graf, I.; Willeit, M.; Eisenegger, C.; Silani, G.

10.1101/832196 — neuroscience — Posted on 2020-02-03

3580 Sustained Activation of PV+ Interneurons in Core Auditory Cortex Enables Robust Divisive Gain Control for Complex and Naturalistic Stimuli

Gothner, T.; Goncalves, P. J.; Sahani, M.; Linden, J. F.; Hildebrandt, K. J.

10.1101/832642 — neuroscience — Posted on 2020-02-03

3581 Connectome-based predictive modeling of individual anxiety

Wang, Z.; S. Goerlich, K.; Ai, H.; Aleman, A.; Luo, Y.; Xu, P.

10.1101/2020.01.30.926980 — neuroscience — Posted on 2020-02-03

3582 Elaboration of host P2X7R-P38MAPK axis involvement against intracellular leishmania donovani by Spergulin-A: a comprehensive study

Mukherjee, N.; Banerjee, S.; Amin, S. A.; Jha, T.; Datta, S.; Das Saha, K.

10.1101/2019.12.14.876391 — molecular biology — Posted on 2020-02-03

3583 Single cell transcriptome profiling of the Atlantic cod immune system

Guslund, N. C.; Solbakken, M. H.; Jakobsen, K. S.; Qiao, S.-W.

10.1101/2020.01.31.926410 — immunology — Posted on 2020-02-03

3584 Broadly neutralizing plasma antibodies effective against diverse autologous circulating viruses in infants with multivariant HIV-1 infection.

Mishra, N.; Sharma, S.; Dobhal, A.; Kumar, S.; Chawla, H.; Singh, R.; Makhdoomi, M. A.; Das, B. K.; Lodha, R.; Kabra, S. K.; Luthra, K.

10.1101/837039 — immunology — Posted on 2020-02-03

3585 Smchd1 is a maternal effect gene required for autosomal imprinting

Wanigasuriya, I.; Gouil, Q.; Kinkel, S. A.; Tapia del Fierro, A.; Beck, T.; Roper, E. E. A.; Breslin, K.; Stringer, J.; Hutt, K.; Lee, H. J.; Keniry, A.; Ritchie, M. E.; Blewitt, M. E.

10.1101/2020.01.20.913376 — genomics — Posted on 2020-02-03

3586 Interdependence between confirmed and discarded cases of dengue, chikungunya and Zika viruses in Brazil: A multivariate time-series analysis

Oliveira, J. F.; Rodrigues, M. S.; Skalinski, L. M.; Santos, A. E.; Costa, L. C.; Cardim, L. L.; Paixao, E. S.; Costa, M. d. C. N.; Oliveira, W. K.; Barreto, M. L.; Teixeira, M. G.; Andrade, R. F. S.

10.1101/708743 — epidemiology — Posted on 2020-02-03

3587 Describing macroecological patterns in microbes: Approaches for comparative analyses of operational taxonomic unit read number distribution with a case study of global oceanic bacteria

Nakadai, R.; Okazaki, Y.; Matsuoka, S.

10.1101/778829 — ecology — Posted on 2020-02-03

3588 Interplay between the paradox of enrichment and nutrient cycling in food webs

Quevreux, P.; Barot, S.; Thebault, E.

10.1101/276592 — ecology — Posted on 2020-02-03

3589 When Two are Better than One: Modeling the Mechanisms of Antibody Mixtures

Einav, T.; Bloom, J. D.

10.1101/808394 — biophysics — Posted on 2020-02-03

3590 Highly Distinguished Amino Acid Sequences of 2019-nCoV (Wuhan Coronavirus)

Beal, J.; Mitchell, T.; Wyschogrod, D.; Manthey, J.; Clore, A.

10.1101/2020.01.31.929497 — genetics — Posted on 2020-02-02

3591 Metabolite sequestration enables rapid recovery from fatty acid depletion in Escherichia coli

Hartline, C. J.; Mannan, A. A.; Liu, D.; Zhang, F.; Oyarzun, D. A.

10.1101/590943 — systems biology — Posted on 2020-02-02

3592 LncRNA GAS5 attenuates fibroblast activation through inhibiting Smad3-mediated myofibroblast marker gene expression.

Tang, R.; Wang, Y.-C.; Mei, X.; Shi, N.; Sun, C.; Ran, R.; Zhang, G.; Li, W.; Staveley-O'Carroll, K.; Li, G.; Chen, S.-Y.

10.1101/2020.02.01.930412 — molecular biology — Posted on 2020-02-02

3593 Argonaute-mediated system for supersensitive and multiplexed detection of rare mutations

Liu, Q.; Guo, X.; Xun, G.; Li, Z.; Chong, Y.; Yang, L.; Wang, H.; Zhang, F.; Luo, S.; Deng, Z.; Li, K.; Feng, Y.

10.1101/803841 — bioengineering — Posted on 2020-02-02

3594 Core-2 O-glycans are required for Galectin-3 interaction with the osteoarthritis related protein lubricin

10.1101/2019.12.20.884148 — biochemistry — Posted on 2020-02-02

3595 Host and infectivity prediction of Wuhan 2019 novel coronavirus using deep learning algorithm

Guo, Q.; Li, M.; Wang, C.; Fang, Z.; Wang, P.; Tan, J.; Wu, S.; Xiao, Y.; Zhu, H.

10.1101/2020.01.21.914044 — systems biology — Posted on 2020-02-02

3596 Functional Importance of Second Heart Field-derived Cells During Thoracic Aortic Aneurysm Formation

Sawada, H.; Higashi, H.; Debra, R. L.; Chen, J. Z.; Moorleghen, J. J.; Howatt, D. A.; Lu, H. S.; Morgan, S.; Singh, S. A.; Aikawa, M.; Majesky, M. W.; Daugherty, A.

10.1101/2020.02.02.930917 — pathology — Posted on 2020-02-02

3597 Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis

Back, P. S.; O'Shaughnessy, W. J.; Moon, A. S.; Dewangan, P. S.; Wohlschlegel, J. L.; Sha, J.; Bradley, P.; Reese, M. L.

10.1101/2020.02.02.931089 — microbiology — Posted on 2020-02-02

3598 A macro-ecological approach to predators' functional response

Barbier, M.; Wojcik, L.; Loreau, M.

10.1101/832220 — ecology — Posted on 2020-02-02

3599 Structure and dynamics of a lipid nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations

Bengtsen, T.; Holm, V. L.; Kjolbye, L. R.; Midtgaard, S. R.; Johansen, N. T.; Bottaro, S.; Schiott, B.; Arleth, L.; Lindorff-Larsen, K.

10.1101/734822 — biophysics — Posted on 2020-02-02

3600 Inferring translational heterogeneity from ribosome profiling data

do Couto Bordignon, P.; Pechmann, S.

10.1101/866582 — bioinformatics — Posted on 2020-02-02

3601 Complete genome characterisation of a novel coronavirus associated with severe human respiratory disease in Wuhan, China

Wu, F.; Zhao, S.; Yu, B.; Chen, Y.-M.; Wang, W.; Hu, Y.; Song, Z.-G.; Tao, Z.-W.; Tian, J.-H.; Pei, Y.-Y.; Yuan, M.-L.; Zhang, Y.-L.; Dai, F.-H.; Liu, Y.; Wang, Q.-M.; Zheng, J.-J.; Xu, L.; Holmes, E. C.; Zhang, Y.-Z.

10.1101/2020.01.24.919183 — pathology — Posted on 2020-02-02

3602 Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls

King, L. S.; Dennis, E. L.; Humphreys, K. L.; Thompson, P. M.; Gotlib, I. H.

10.1101/2020.01.24.918847 — developmental biology — Posted on 2020-02-02

3603 Upscaling surveillance of tick-borne pathogens in the French Caribbean islands

Gondard, M.; Delannoy, S.; Pinarello, V.; Aprelon, R.; Devillers, E.; Galon, C.; Pradel, J.; Vayssier-Taussat, M.; Albina, E.; Moutailler, S.

10.1101/532457 — epidemiology — Posted on 2020-02-02

3604 Discovery of biased orientations of human DNA motif sequences affecting enhancer-promoter interactions and transcription of genes

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2020-02-02

3605 Potent neutralization of 2019 novel coronavirus by recombinant ACE2-Ig

Lei, C.; Fu, W.; Qian, K.; Li, T.; Zhang, S.; Ding, M.; Hu, S.

10.1101/2020.02.01.929976 — bioengineering — Posted on 2020-02-02

3606 Fe-S protein assembly involves bipartite client binding and conformational flexibility in the CIA targeting complex

Kassube, S. A.; Thomae, N. H.

10.1101/2020.02.01.930206 — biochemistry — Posted on 2020-02-02

3607 A wireless, implantable optoelectrochemical probe for optogenetic stimulation and dopamine detection

Sheng, X.

10.1101/2020.02.02.926782 — bioengineering — Posted on 2020-02-02

3608 Covalent Protein Painting Reveals Structural Changes in the Proteome in Alzheimer Disease

Bamberger, T. C.; Pankow, S.; Martinez-Bartolome, S.; Ma, M.; Diedrich, J. K.; Rissman, R. A.; Yates, J. R.

10.1101/2020.01.31.929117 — biochemistry — Posted on 2020-02-02

3609 Analysis of translating mitoribosome reveals functional characteristics of protein synthesis in mitochondria of fungi

Naschberger, A.; Itoh, Y.; Mortezaei, N.; Herrmann, J.; Amunts, A.

10.1101/2020.01.31.929331 — biochemistry — Posted on 2020-02-02

3610 Comparison of solitary and collective foraging strategies of Caenorhabditis elegans in patchy food distributions

Ding, S. S.; Muhle, L. S.; Brown, A. E. X.; Schumacher, L. J.; Endres, R.

10.1101/744649 — animal behavior and cognition — Posted on 2020-02-02

3611 The Superior Frontal Longitudinal Tract: Connection between the Dorsal Premotor and the Dorsolateral Prefrontal Cortices

Bakhit, M.; Fujii, M.; Hiruta, R.; Yamada, M.; Iwami, K.; Sato, T.; Saito, K.

10.1101/2020.02.01.930552 — neuroscience — Posted on 2020-02-02

3612 Detection of hypermucoviscous Klebsiella pneumoniae sequence type 86 capsular type K2 in South America as an unexpected cause of a fatal outbreak in captivity marmosets

Guerra, J.; Fernandes, N.; Santos, A.; Barrel, J.; Petri, B.; Milanelo, L.; Tiba-Casas, M.; Liserre, A.; Goncalves, C.; Sacchi, C.; Catao-Dias, J.; Camargo, C. H.

10.1101/2020.02.02.930685 — microbiology — Posted on 2020-02-02

3613 Larger bacterial populations evolve heavier fitness trade-offs and undergo greater ecological specialization

Chavhan, Y.; Malusare, S.; Dey, S.

10.1101/2020.02.02.930883 — evolutionary biology — Posted on 2020-02-02

3614 Unification of Environmental Metabolomics with Metacommunity Ecology

Danczak, R. E.; Chu, R. K.; Fansler, S. J.; Goldman, A. E.; Graham, E. B.; Tfaily, M. M.; Toyoda, J. G.; Stegen, J. C.

10.1101/2020.01.31.929364 — ecology — Posted on 2020-02-02

3615 pipeComp, a general framework for the evaluation of computational pipelines, reveals performant single-cell RNA-seq preprocessing tools

Germain, P.-L.; Sonrel, A.; Robinson, M. D.

10.1101/2020.02.02.930578 — bioinformatics — Posted on 2020-02-02

3616 ShearFAST: a user-friendly in vitro toolset for high throughput, inexpensive fluid shear stress experiments.

Smith, T. B.; De Nunzio, A. M.; Patel, K.; Munford, H.; Alam, T.; Powell, O.; Heneghan, N.; Ready, A.; Nath, J.; Ludwig, C.

10.1101/2020.01.31.929513 — cell biology — Posted on 2020-02-02

3617 A synergistic action of sirtuins directly recognizes DNA breaks and potentiates DNA damage response and repair

Meng, F.; Qian, M.; Peng, B.; Wang, X.; Peng, L.; Zheng, K.; Liu, Z.; Tang, X.; Zhang, S.; Sun, S.; Cao, X.; Pang, Q.; Zhao, B.; Ma, W.; Songyang, Z.; Xu, B.; Zhu, W.-G.; Xu, X.; Liu, B.

10.1101/2020.02.01.930172 — biochemistry — Posted on 2020-02-02

3618 Predicting commercially available antiviral drugs that may act on the novel coronavirus (2019-nCoV), Wuhan, China through a drug-target interaction deep learning model

Beck, B. R.; Shin, B.; Choi, Y.; Park, S.; Kang, K.

10.1101/2020.01.31.929547 — microbiology — Posted on 2020-02-02

3619 Relative contribution of non-structural protein 1 in dengue pathogenesis

LEE, P.; TING, D. H. R.; Boey, C. P. H.; TAN, E. T. X.; Chia, J. Z. H.; ONG, L. C.; CHUA, Y. L.; Hapuarachchi, C.; NG, L. C.; ALONSO, S.

10.1101/2020.02.01.929885 — microbiology — Posted on 2020-02-02

3620 Epigenetic mediation of the onset of reproduction in a songbird

Lindner, M.; Laine, V. N.; Verhagen, I.; Viitaniemi, H. M.; Visser, M. E.; van Oers, K.; Husby, A.

10.1101/2020.02.01.929968 — ecology — Posted on 2020-02-02

3621 The cation diffusion facilitator protein MamM's cytoplasmic domain exhibits metal-type dependent binding modes and discriminates against Mn2+

Barber-Zucker, S.; Hall, J.; Froes, A.; Kolusheva, S.; MacMillan, F.; Zarivach, R.

10.1101/2020.02.02.930644 — biophysics — Posted on 2020-02-02

3622 Non-canonical regulation of glycogenolysis and the Warburg phenotype by soluble adenylyl cyclase

Chang, J.-C.; Go, S.; Gilglioni, E. H.; Li, H. L.; Huang, H.-L.; Levin, L. R.; Buck, J.; Verhoeven, A. J.; Oude Elferink, R. P. J.

10.1101/2020.02.02.929901 — biochemistry — Posted on 2020-02-02

3623 Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing

Khoo, K. K.; Galleano, I.; Gasparri, F.; Wieneke, R.; Harms, H.; Poulsen, M. H.; Chua, H. C.; Wulf, M.; Tampe, R.; Pless, S. A.

10.1101/2020.01.31.925495 — synthetic biology — Posted on 2020-02-02

3624 Arabidopsis AZG2, an auxin induced putative cytokinin transporter, regulates lateral root emergence

Tessi, T. M.; Brumm, S.; Winklbauer, E.; Schumacher, B.; Lescano, C. I.; Gonzalez, C. A.; Wanke, D.; Maurino, V.; Harter, K.; Desimone, M.

10.1101/2020.01.31.927970 — plant biology — Posted on 2020-02-02

3625 Disentangling Decision-related Feedforward and Feedback Signals in Human Cortex

Wilming, N.; Murphy, P. R.; Meyniel, F.; Donner, T.

10.1101/2020.02.01.929893 — neuroscience — Posted on 2020-02-02

3626 Elucidation of novel miRNA candidates and their role in unraveling the pathology of Non-Alcoholic Fatty Liver Disease

Biju, B. M.; Chhabra, S. S.; Sarkar, C.

10.1101/2020.01.31.917831 — molecular biology — Posted on 2020-02-02

3627 Generalizability of "GWAS hits" in clinical populations: Lessons from childhood cancer survivors

Im, C.; Qin, N.; Wang, Z.; Qiu, W.; Howell, C. R.; Sapkota, Y.; Moon, W.; Chemaitilly, W.; Gibson, T. M.; Mulrooney, D. A.; Ness, K. K.; Wilson, C. L.; Morton, L. M.; Armstrong, G. T.; Bhatia, S.; Zhang, J.; Hudson, M. M.; Robison, L. L.; Yasui, Y.

10.1101/2020.02.02.930818 — genetics — Posted on 2020-02-02

3628 Metastatic signaling of hypoxia-related genes across TCGA Pan-Cancer types

Lopez-Cortes, A.; Guevara-Ramirez, P.; Guerrero, S.; Ortiz-Prado, E.; Garcia-Cardenas, J. M.; Zambrano, A. K.; Armendariz-Castillo, I.; Perez-Villa, A.; Yumiceba, V.; Varela, N.; Cordova-Bastidas, D.; Leone, P. E.; Paz-y-Mino, C.

10.1101/2020.02.01.930479 — cancer biology — Posted on 2020-02-02

3629 Non-invasive, Real-time Detection of Vascular Disorders in Mice using Bright SWIR-emitting Gold Nanoclusters and Monte Carlo Image Analysis

Yu, Z.; Musnier, B.; Henry, M.; Wegner, K. D.; Chovelon, B.; Desroches-Castan, A.; Fertin, A.; Resch-Genger, U.; Coll, J.-l.; Bailly, S.; Usson, Y.; Josserand, V.; Le Guevel, X.

10.1101/2020.01.31.928382 — bioengineering — Posted on 2020-02-02

3630 Multiplexed whole animal imaging with reversibly switchable optoacoustic proteins

Mishra, K.; Stankevych, M.; Fuenzalida-Werner, J. P.; Grassmann, S.; Gujrati, V.; Klemm, U.; Buchholz, V. R.; Ntziachristos, V.; Stiel, A. C.

10.1101/2020.02.01.930222 — biochemistry — Posted on 2020-02-02

3631 Phosphorylation of Elovl5 changes its substrate preference to synthesize Mead acid in response to essential fatty acid deficiency

Hayashi, Y.; Yamano, M.; Kono, N.; Arai, H.; Fujiwara, Y.; Ichi, I.

10.1101/2020.01.31.929224 — biochemistry — Posted on 2020-02-02

3632 Entner-Doudoroff pathway and Non-OxPPP bypasses glycolysis and OxPPP in Ralstonia solanacearum

Jyoti, P.; Shree, M.; Joshi, C.; Prakash, T.; Ray, S. K.; Satapathy, S. S.; Masakapalli, S. K.

10.1101/2020.01.31.929778 — systems biology — Posted on 2020-02-02

3633 Selective augmentation of intestinal immunity by CD22-dependent SHP-1 control of β7 integrin expression.

Ballet, R.; Brandl, C.; Feng, N.; Berri, J.; Cheng, J.; Ocon, B.; Alborzian Deh Sheikh, A.; Marki, A.; Abram, C. L.; Lowell, C. A.; Tsubata, T.; Greenberg, H. B.; Macauley, M. S.; Ley, K.; Nitschke, L.; Butcher, E.

10.1101/2020.01.31.929687 — immunology — Posted on 2020-02-02

3634 Loss of a conserved MAPK causes catastrophic failure in assembly of a specialized cilium-like structure in Toxoplasma gondii

O'Shaugnessy, W. J.; Hu, X.; Beraki, T.; McDougal, M.; Reese, M. L.

10.1101/2020.02.02.931022 — cell biology — Posted on 2020-02-02

3635 Challenging a preconception: Optoacoustic spectrum differs from the absorption spectrum of proteins and dyes for molecular imaging

Fuenzalida Werner, J. P.; Huang, Y.; Mishra, K.; Chmyrov, A.; Ntziachristos, V.; Stiel, A. C.

10.1101/2020.02.01.930230 — biophysics — Posted on 2020-02-02

3636 G-baToN: a versatile cell-cell interaction reporter system.

Tang, R.; Murray, C. W.; Linde, I.; Kramer, N. J.; Tsai, M. K.; Chen, L.; Cai, H.; Gitler, A. D.; Engleman, E.; Winslow, M. M.

10.1101/2020.02.01.929877 — bioengineering — Posted on 2020-02-02

3637 Engineering Selective Molecular Tethers to Enhance Suboptimal Drug Properties

Dogan, A. B.; von Recum, H. A.

10.1101/2020.02.01.929356 — bioengineering — Posted on 2020-02-02

3638 Dissolved oxygen dynamics reveal biogeochemical tipping points driven by river corridor hydrology

Kaufman, M. H.; Ghosh, R. N.; Grate, J.; Shooltz, D. D.; Freeman, M. J.; Ball, T. M.; Loloee, R.; McIntire, C. W.; Wells, J.; Strickland, C.; Vermeul, V.; Rod, K. A.; Mackley, R. D.; Lin, X.; Ren, H.; Stegen, J. C.

10.1101/2020.01.31.929505 — biochemistry — Posted on 2020-02-02

3639 Layer-dependent multiplicative effects of spatial attention on contrast responses in human early visual cortex

Guo, F.; Liu, C.; Qian, C.; Zhang, Z.; Sun, K.; Wang, D. J.; He, S.; Zhang, P.

10.1101/2020.02.01.926303 — neuroscience — Posted on 2020-02-02

3640 The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation

Rashad, S.; Han, X.; Sato, K.; Mishima, E.; Abe, T.; Tominaga, T.; Niizuma, K.

10.1101/2020.01.31.928234 — molecular biology — Posted on 2020-02-02

3641 LncRNA GAS5 attenuates fibroblast activation through inhiting Smad3-mediated myofibroblast marker gene expression.

Tang, R.; Wang, Y.-C.; Mei, X.; Shi, N.; Sun, C.; Ran, R.; Zhang, G.; Li, W.; Staveley-O'Carroll, K.; Li, G.; Chen, S.-Y.

10.1101/2020.02.01.930412 — molecular biology — Posted on 2020-02-02

3642 A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions

Segireddy, R. R.; Dundas, K.; Knoeckel, J.; Galaway, F.; Wood, L.; Wright, G. J.; Douglas, A. D.

10.1101/2020.02.02.929190 — microbiology — Posted on 2020-02-02

3643 Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease

Govaere, O.; Martinez-Lopez, N.; Petersen, S. K.; Mancina, R. M.; Jamialahmadi, O.; Lassen, P. B.; Darlay, R.; Peltier, J.; Younes, R.; Tiniakos, D.; Aithal, G. P.; Allison, M.; Vacca, M.; Yki-Jarvinen, H.; Dufour, J.-F.; Ekstedt, M.; Francque, S.; Petta, S.; Bugianesi, E.; Schattenberg, J. M.; Day, C. P.; Cordell, H. J.; Clement, K.; Romeo, S.; Ratziu, V.; Daly, A. K.; Anstee, Q. M.; Trost, M.; Hartlova, A.

10.1101/2020.02.01.930115 — immunology — Posted on 2020-02-02

3644 TRIM67 Regulates Exocytic Mode and Neuronal Morphogenesis via SNAP47

Urbina, F. l.; Menon, S.; Goldfarb, D.; Major, M. B.; Gupton, S. L.

10.1101/2020.02.01.930404 — cell biology — Posted on 2020-02-02

3645 Cellular internalization of Godanti Bhasma (anhydrous CaSO4) induces massive cytoplasmic reversible vacuolation and survival response of mammalian cells.

Das, S. K.; Joshi, A.; Sharma, V.; Bisht, L.; Das, N.; Sharma, N.; Shukla, S.; Mehra, D.; Joshi, K.; Balkrishna, A.; Dhara, S.

10.1101/2020.02.01.930594 — cell biology — Posted on 2020-02-02

3646 ADAR1 editing dependency in triple-negative breast cancer

Kung, C.-P.; Cottrell, K. A.; Ryu, S.; Bramel, E. R.; Kladney, R. D.; Bross, E. A.; Maggi, L.; Weber, J. D.

10.1101/2020.01.31.928911 — cancer biology — Posted on 2020-02-02

3647 Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor

Jaiswal, A.; Gautam, P.; Pietila, E. A.; Timonen, S.; Nordstrom, N.; Tanoli, Z.; Sipari, N.; Lehti, K.; Wennerberg, K.; Aittokallio, T.

10.1101/2020.01.31.929372 — cancer biology — Posted on 2020-02-02

3648 Cytoskeletal Tubulin Competes with Actin to Increase Deformability of Metastatic Melanoma Cells

Higgins, G.; Peres, J.; Abdalrahman, T.; Zaman, M. H.; Lang, D.; Prince, S.; Franz, T.

10.1101/2020.02.01.929919 — cancer biology — Posted on 2020-02-02

3649 Loss of COX4i1 leads to combined respiratory chain deficiency and impaired mitochondrial proteosynthesis

Cunatova, K.; Pajuelo Reguera, D.; Vrbacky, M.; Fernandez-Vizarra, E.; Ding, S.; Fearnley, I.; Zeviani, M.; Houstek, J.; Mracek, T.; Pecina, P.

10.1101/2020.01.31.925420 — biochemistry — Posted on 2020-02-02

3650 CLOCK-induced upregulated HMGB1 resulting in circadian rhythms disruption of inflammatory microglia contributes to non-dipper hypertension in stressed rats

Zhang, S.; Hu, L.; Xia, C.

10.1101/2020.02.02.930800 — physiology — Posted on 2020-02-02

3651 Improving multi-site autism classification based on site-dependence minimisation and second-order functional connectivity

Kunda, M.; Zhou, S.; Gong, G.; Lu, H.

10.1101/2020.02.01.930073 — neuroscience — Posted on 2020-02-02

3652 Inferring Neural Population Spiking Rate from Wide-Field Calcium Imaging

Stern, M.; Shea-Brown, E.; Witten, D.

10.1101/2020.02.01.930040 — neuroscience — Posted on 2020-02-02

3653 Biofilm Formation by Staphylococcus aureus is Triggered by a Drop in the Levels of the Second Messenger cyclic-di-AMP

Syed, A. K.; Vickery, C. R.; Lenhart, T.; Llewellyn, E.; Walker, S.; Losick, R.

10.1101/2020.01.31.929125 — microbiology — Posted on 2020-02-02

3654 The branched chain aminotransferase IlvE promotes growth, stress resistance, and pathogenesis of Listeria monocytogenes

Passalacqua, K. D.; Zhou, T.; Washington, T. A.; Abuaita, B. H.; Sonenshein, A. L.; O'Riordan, M.

10.1101/2020.01.31.929828 — microbiology — Posted on 2020-02-02

3655 An allometric scaling approach to estimate epiphytic bryophyte biomass in tropical montane cloud forests

Lai, G.-Y.; Liu, H.-C.; Kuo, A. J.; Huang, C.-y.

10.1101/2020.02.01.928515 — ecology — Posted on 2020-02-02

3656 Sorting liposomes of distinct sizes by DNA-brick assisted centrifugation

Yang, Y.; Wu, Z.; Wang, L.; Zhou, K.; Xia, K.; Xiong, Q.; Xiong, Y.; Melia, T. J.; Karatekin, E.; Gu, H.; Lin, C.

10.1101/2020.02.01.930321 — biophysics — Posted on 2020-02-02

3657 Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems

Yu, T. C.; Liu, W. L.; Brinck, M. S.; Davis, J. E.; Shek, J.; Bower, G.; Einav, T.; Insigne, K. D.; Phillips, R.; Kosuri, S.; Urtecho, G.

10.1101/2020.01.31.928689 — synthetic biology — Posted on 2020-02-02

3658 SICD6mA: Identifying the 6mA Sites on Human and Rice Genomes using Deep Memory Network

Wenzhong, L.

10.1101/2020.02.02.930776 — bioinformatics — Posted on 2020-02-02

3659 The E. coli NudL enzyme is a Nudix hydrolase that cleaves CoA and its derivatives

Spangler, J. R.; Huang, F.

10.1101/2020.01.31.929182 — biochemistry — Posted on 2020-02-02

3660 The influence of insulin therapy on measurements of optical coherence tomography parameters in diabetic patients without retinopathy

Zhou, D.; Wang, W.; Zhou, R.; He, M.; Gong, X.; Li, Y.; Huang, W.

10.1101/2020.01.31.928184 — physiology — Posted on 2020-02-02

3661 Analysis of social swimming dynamics in the Mexican cavefish

Patch, A.; Paz, A.; Holt, K.; Duboue, E. R.; Kowalko, J. E.; Keene, A. C.; Fily, Y.

10.1101/2020.01.31.929323 — animal behavior and cognition — Posted on 2020-02-02

3662 Myeloid cell mPGES-1 mediates inflammatory pain hypersensitivity in mice.

Chen, L.; Yang, G.; Cormode, D. P.; Saigal, A.; Madhavan, S.; Mazaleuskaya, L. L.; Grant, G. R.; FitzGerald, G. A.; Grosser, T.

10.1101/2020.01.31.929422 — pharmacology and toxicology — Posted on 2020-02-02

3663 Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways

Zhang, S.; Kim, B.; Zhu, X.; Gui, X.; Wang, Y.; Lan, Z.; Prabhu, P.; Fond, K.; Wang, A.; Guo, F.

10.1101/2020.01.31.929661 — neuroscience — Posted on 2020-02-02

3664 IL4-driven microglia modulate stress resilience through BDNF-dependent neurogenesis

Zhang, J.; Rong, P.; Zhang, L.; He, H.; Zhou, T.; Fan, Y.; Mo, L.; Zhao, Q.; Han, Y.; Li, S.; Wang, Y.; Yan, W.; Chen, H.; You, Z.

10.1101/2020.02.01.929646 — neuroscience — Posted on 2020-02-02

3665 Transcranial in vivo detection of Aβ at single plaque resolution with large-field multifocal illumination fluorescence microscopy

Ni, R.; Chen, Z.; Shi, G.; Villois, A.; Zhou, Q.; Arosio, P.; Nitsch, R. M.; Nilsson, P. R.; Klohs, J.; Razansky, D.

10.1101/2020.02.01.929844 — neuroscience — Posted on 2020-02-02

3666 Sleep-like behavior is a fundamental property of the tripartite synapse

Joshi, S.; Joshi, A.; Joshi, N.

10.1101/2020.02.02.917633 — neuroscience — Posted on 2020-02-02

3667 OpenMonkeyStudio: Automated Markerless Pose Estimation in Freely Moving Macaques

Bala, P. C.; Eisenreich, B. R.; Yoo, S. B. M.; Hayden, B. Y.; Park, H. S.; Zimmermann, J.

10.1101/2020.01.31.928861 — neuroscience — Posted on 2020-02-02

3668 Segment-specific orientation of the dorsal and ventral roots for precise therapeutic targeting of human spinal cord

Mendez, A.; Islam, R.; Latypov, T.; Basa, P.; Joseph,, O.; Knudsen, B.; Siddiqui, A. M.; Summer, P.; Staehnke, L. J.; Grahn, P. J.; Lachman, N.; Windebank, A. M.; Lavrov, I. A.

10.1101/2020.01.31.928804 — neuroscience — Posted on 2020-02-02

3669 Nuclear sensing of mitochondrial DNA breaks enhances immune surveillance

Tigano, M.; Vargas, D. C.; Tremblay-Belzile, S.; Fu, Y.; Sfeir, A.

10.1101/2020.01.31.929075 — molecular biology — Posted on 2020-02-02

3670 Single-molecule imaging of telomerase RNA reveals a Recruitment-Retention model for telomere elongation

Laprade, H.; Querido, E.; Smith, M. J.; Guerit, D.; Crimmins, H.; Conomos, D.; Pourret, E.; Chartrand, P.; Sfeir, A.

10.1101/2020.01.31.929026 — molecular biology — Posted on 2020-02-02

3671 A guided approach for subtomogram averaging of challenging macromolecular assemblies

Grotjahn, D.; Chowdhury, S.; Lander, G. C.

10.1101/2020.02.01.930297 — molecular biology — Posted on 2020-02-02

3672 Widespread divergent transcription from prokaryotic promoters

Warman, E.; Forrest, D.; Wade, J. T.; Grainger, D. C.

10.1101/2020.01.31.928960 — molecular biology — Posted on 2020-02-02

3673 Gut lymph purification regulates monocyte activity in rats with ischemia-reperfusion injury-induced sepsis

Zhang, W.; Chen, J.; Jin, C.; Zhang, S.; Gu, J.; Shi, M.

10.1101/2020.02.02.930610 — molecular biology — Posted on 2020-02-02

3674 Carbohydrate complexity structures stable diversity in gut-derived microbial consortia under high dilution pressure

Yao, T.; Chen, M.-H.; Lindemann, S. R.

10.1101/2020.01.31.929760 — microbiology — Posted on 2020-02-02

3675 Metagenomic Insights into Microbial Metabolisms of a Sulfur-Influenced Glacial Ecosystem

Trivedi, C. B.; Stamps, B. W.; Lau, G. E.; Grasby, S. E.; Templeton, A.; Spear, J. R.

10.1101/2020.01.31.929786 — microbiology — Posted on 2020-02-02

3676 The ECF sigma factor PvdS regulates the type I-F CRISPR-Cas system in Pseudomonas aeruginosa.

Ahator, S. D.; Wang, J.; Zhang, L.

10.1101/2020.01.31.929752 — microbiology — Posted on 2020-02-02

3677 Generation of Xylose-inducible promoter tools for Pseudomonas species and their use in implicating a role for the Type II secretion system protein XcpQ in inhibition of corneal epithelial wound closure

Callaghan, J. D.; Stella, N. A.; Lehner, K. M.; Treat, B. R.; Brothers, K. M.; St. Leger, A. J.; Shanks, R. M.

10.1101/2020.01.31.929794 — microbiology — Posted on 2020-02-02

3678 Cross-feeding between Thauera aminoaromatica and Rhodococcus pyridinivorans drove quinoline biodegradation in a denitrifying bioreactor

Wu, X.; Wu, X.; Li, J.; Wu, Q.; Ma, Y.; Sui, W.; Zhao, L.; Zhang, X.

10.1101/2020.01.31.929745 — microbiology — Posted on 2020-02-02

3679 FK506-binding protein FklB is involved in biofilm formation through its peptidyl-prolyl isomerase activity

Zografou, C.; Dimou, M.; Katinakis, P.

10.1101/2020.02.01.930347 — microbiology — Posted on 2020-02-02

3680 Thermogenic hydrocarbons sustain diverse subseafloor microbial communities in deep sea cold seep sediments

10.1101/2020.02.02.928283 — microbiology — Posted on 2020-02-02

3681 A Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by Zika Virus in Macaques

Van Rompay, K. K. A.; Coffey, L. L.; Kapoor, T.; Gazumyan, A.; Keesler, R. I.; Jurado, A.; Peace, A.; Agudelo, M.; Watanabe, J.; Usachenko, J.; Singapuri, A.; Immareddy, R.; Ardeshir, A.; Stuart, J. B.; Bournazos, S.; Ravetch, J. V.; Balderes, P. J.; Lorenz, I. C.; Esswein, S. R.; Keeffe, J.; Bjorkman, P. J.; Wang, Q.; Rice, C. M.; MacDonald, M. R.; Nussenzweig, M. C.; Robbiani, D. F.

10.1101/2020.01.31.926899 — immunology — Posted on 2020-02-02

3682 Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

Antanasijevic, A.; Ueda, G.; Copps, J.; Brouwer, P. J.; Huang, D.; Allen, J. D.; Cottrell, C. A.; Yasmeen, A.; Sewall, L. M.; Bontjer, I.; Ketas, T. J.; Turner, H. L.; Berndsen, Z. T.; Klasse, P. J.; Crispin, M.; Nemazee, D.; Moore, J. P.; Sanders, R. W.; King, N.; Baker, D.; Ward, A. B.

10.1101/2020.01.31.929273 — immunology — Posted on 2020-02-02

3683 LAG3 is a Central Regulator of NK Cell Cytokine Production

Narayanan, S.; Ahl, P. J.; Au, V. B.; Kaliaperumal, N.; Lim, S. G.; Wang, C.-I.; Fairhurst, A.-M.; Connolly, J. E.

10.1101/2020.01.31.928200 — immunology — Posted on 2020-02-02

3684 Phylogenomic resolution of sea spider diversification through integration of multiple data classes

10.1101/2020.01.31.929612 — evolutionary biology — Posted on 2020-02-02

3685 Evolution of sperm morphology in Daphnia

duneau, d.; Moest, M.; Ebert, D.

10.1101/2020.01.31.929414 — evolutionary biology — Posted on 2020-02-02

3686 Effects of host species identity and diet on biodiversity of oral and rectal microbiomes of Puerto Rican bats

Presley, S. J.; Graf, J.; Hassan, A. F.; Sjodin, A. R.; Willig, M. R.

10.1101/2020.01.31.928994 — ecology — Posted on 2020-02-02

3687 Reciprocal transplant experiment in lakes with disparate trophic states show resolution dependent partial functional redundancy

Tandon, K.; Wan, M.-T.; Yang, C.-C.; Yang, S.-H.; Baatar, B.; Chiu, C.-Y.; Tsai, J.-W.; Liu, W.-C.; Ng, C. S.; Tang, S.-L.

10.1101/2020.02.01.930198 — ecology — Posted on 2020-02-02

3688 Impact of prior and projected climate change on US Lyme disease incidence

Couper, L. I.; MacDonald, A. J.; Mordecai, E. A.

10.1101/2020.01.31.929380 — ecology — Posted on 2020-02-02

3689 Microbial community assembly in a multi-layer dendritic metacommunity

Wisnoski, N. I.; Lennon, J. T.

10.1101/2020.01.31.929562 — ecology — Posted on 2020-02-02

3690 Scleraxis-Lineage Cell Depletion Improves Tendon Healing

Best, K. T.; Mora, K. E.; Buckley, M. R.; Loiselle, A. E.

10.1101/2020.02.01.930255 — cell biology — Posted on 2020-02-02

3691 Klp2 and Ase1 synergize to maintain meiotic spindle stability during metaphase I

Zheng, F.; Dong, F.; Yu, S.; Li, T.; Jian, Y.; Nie, L.; Fu, C.

10.1101/2020.01.31.929729 — cell biology — Posted on 2020-02-02

3692 Development of a high-throughput radial migration device

Oliver, C. R.; Little, A. C.; Westerhof, T. M.; Pathanjeli, P.; Yates, J. A.; Merajver, S. D.

10.1101/2020.01.31.928879 — bioengineering — Posted on 2020-02-02

3693 Measuring Nestedness: A comparative study of the performance of different metrics

Payrato-Borras, C.; Hernandez, L.; Moreno, Y.

10.1101/2020.01.31.928945 — ecology — Posted on 2020-02-02

3694 Spatial transcriptomics of tumor microenvironment in formalin-fixed paraffin-embedded breast cancer

Romanens, L.; Chaskar, P.; Tille, J.-C.; Ryser, S.; Liaudet, N.; Hu-Heimgartner, K.; Heimgartner, K.; Kaya, G.; Tsantoulis, P.; Labidi-Galy, S. I.

10.1101/2020.01.31.928143 — cancer biology — Posted on 2020-02-02

3695 Harmine enhances the activity of the HIV-1 latency-reversing agents ingenol A and SAHA

Taylor, J. P.; Armitage, L. H.; Aldridge, D. L.; Cash, M. N.; Wallet, M. A.

10.1101/2020.01.31.927368 — microbiology — Posted on 2020-02-02

3696 ImmunoPET as Stoichiometric Sensor for Glypican-3 in Models of Hepatocellular Carcinoma

Kelada, O. J.; Gutsche, N. T.; Bell, M.; Berman, R. M.; Baidoo, K. E.; Warner, B. M.; Szajek, L. P.; Hong, J.; Ho, M.; Choyke, P. L.; Escorcia, F. E.

10.1101/2020.01.31.926972 — cancer biology — Posted on 2020-02-02

3697 FLAME: Macroscopic imaging with microscopic resolution. Optical biopsy of human skin

Fast, A.; Lal, A.; Durkin, A. F.; Zachary, C. B.; Ganesan, A. K.; Balu, M.

10.1101/2020.01.31.927590 — bioengineering — Posted on 2020-02-02

3698 Stochastic logistic models reproduce experimental time series of microbial communities

Descheemaeker, L.; de Buyl, S.

10.1101/2020.01.31.928697 — systems biology — Posted on 2020-02-02

3699 Retrograde induction of phyB orchestrates ethylene-auxin hierarchy to regulate growth

Jiang, J.; Xiao, Y.; Hu, W.; Chen, H.; Zeng, L.; Ke, H.; Ditengou, F. A.; Devisetty, U. K.; Palme, K.; Maloof, J. N.; Dehesh, K.

10.1101/2020.01.31.929133 — plant biology — Posted on 2020-02-02

3700 Annotating Gene Ontology terms for protein sequences with the Transformer model

Duong, D. B.; Gai, L.; Uppunda, A.; Le, D.; Eskin, E.; Li, J. J.; Chang, K.-W.

10.1101/2020.01.31.929604 — bioinformatics — Posted on 2020-02-02

3701 Episodic Diversifying Selection, Recombination, and Symbiont Capture Characterize the Evolutionary History of Maternally-transmitted Clam Symbionts

Young, C. R.

10.1101/2020.02.01.930370 — genomics — Posted on 2020-02-02

3702 High contiguity de novo genome sequence assembly of Trifoliate yam (Dioscorea dumetorum) using long read sequencing

Siadjeu, C.; Pucker, B.; Viehöver, P.; Albach, D.; Weisshaar, B.

10.1101/2020.01.31.928630 — genomics — Posted on 2020-02-02

3703 Identifying Longevity Associated Genes by Integrating Gene Expression and Curated Annotations

Townes, F. W.; Miller, J. W.

10.1101/2020.01.31.929232 — genomics — Posted on 2020-02-02

3704 DisCovER: distance-based covariational threading for weakly homologous proteins

Bhattacharya, S.; Roche, R.; Bhattacharya, D.

10.1101/2020.01.31.923409 — bioinformatics — Posted on 2020-02-02

3705 DUBS: A Framework for Developing Directory of Useful Benchmarking Sets for Virtual Screening

Fine, J.; Muhoberac, M.; Fraux, G.; Chopra, G.

10.1101/2020.01.31.929679 — bioinformatics — Posted on 2020-02-02

3706 A Novel Multiplex qPCR Assay for Detection of Plasmodium falciparum with Histidine-rich Protein 2 and 3 (pfhrp2 and pfhrp3) Deletions in Polyclonal Infections

10.1101/2020.01.31.928986 — genetics — Posted on 2020-02-02

3707 Variance-stabilized units for sequencing-based genomic signals

Bayat, F.; Libbrecht, M. W.

10.1101/2020.01.31.929174 — bioinformatics — Posted on 2020-02-02

3708 Fast and accurate assembly of Nanopore reads via progressive error correction and adaptive read selection

Chen, Y.; Nie, F.; Xie, S.-Q.; Zheng, Y.-F.; Bray, T.; Dai, Q.; Wang, Y.-X.; Huang, Z.-J.; Wang, D.-P.; He, L.-J.; Luo, F.; Wang, J.-X.; Liu, Y.-Z.; Xiao, C.-L.

10.1101/2020.02.01.930107 — bioinformatics — Posted on 2020-02-02

3709 Meso-limbic Gene Expression Findings from Mouse Cocaine Self-Administration Recapitulate Human Cocaine Use Disorder

Huggett, S. B.; Bubier, J. A.; Chesler, E. J.; Palmer, R. C.

10.1101/2020.01.31.929406 — bioinformatics — Posted on 2020-02-02

3710 Non-negative Independent Factor Analysis for single cell RNA-seq

Mao, W.; Baran Pouyan, M.; Kostka, D.; Chikina, M.

10.1101/2020.01.31.927921 — bioinformatics — Posted on 2020-02-02

3711 DELPHI: accurate deep ensemble model for protein interaction sites prediction

Li, Y.; Ilie, L.

10.1101/2020.01.31.929570 — bioinformatics — Posted on 2020-02-02

3712 Artificial-Cell-Type Aware Cell Type Classification in CITE-seq

Lian, Q.; Xin, H.; Ma, J.; Konnikova, L.; Chen, W.; Gu, J.; Chen, K.

10.1101/2020.01.31.928010 — bioinformatics — Posted on 2020-02-02

3713 rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments

Chow, E. Y.-C.; Lyu, K.; Kwok, C. K.; Chan, T.-F.

10.1101/2020.02.01.929851 — bioinformatics — Posted on 2020-02-02

3714 Functional biological paths altered in Alzheimer's disease: from genes to bile acids

Gorijala, P.; Nho, K.; Risacher, S. L.; Kaddurah-Daouk, R.; Saykin, A. J.; Yan, J.

10.1101/2020.01.31.929554 — bioinformatics — Posted on 2020-02-02

3715 QDeep: distance-based protein model quality estimation by residue-level ensemble error classifications using stacked deep residual neural networks

Shuvo, M. H.; Bhattacharya, S.; Bhattacharya, D.

10.1101/2020.01.31.928622 — bioinformatics — Posted on 2020-02-02

3716 Estimates of autozygosity through runs of homozygosity in farmed coho salmon

Yoshida, G. M.; Caceres, P.; Marin Nahuelpi, R.; Koop, B. F.; Yanez, J.

10.1101/2020.02.01.930065 — genomics — Posted on 2020-02-02

3717 Transcriptomic analysis of dystonia-associated genes reveals functional convergence within specific cell types and shared neurobiology with psychiatric disorders

Mencacci, N. E.; Reynolds, R. H.; Garcia Ruiz, S.; Vandrovcova, J.; Forabosco, P.; UK Brain Expression Consortium, ; International Parkinson Disease Genomics Consortium, ; Weale, M.; Bhatia, K. P.; Hardy, J.; Botia, J. A.; Ryten, M.

10.1101/2020.01.31.928978 — genetics — Posted on 2020-02-02

3718 Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes

Cleemput, S.; Dumon, W.; Fonseca, V.; Abdool Karim, W.; Giovanetti, M.; Alcantara, L. C. J.; Deforche, K.; de Oliveira, T.

10.1101/2020.01.31.928796 — bioinformatics — Posted on 2020-02-02

3719 talklr uncovers ligand-receptor mediated intercellular crosstalk

Wang, Y.

10.1101/2020.02.01.930602 — bioinformatics — Posted on 2020-02-02

Pradhan, P.; Pandey, A. K.; Mishra, A.; Gupta, P.; Tripathi, P. K.; Menon, M. B.; Gomes, J.; Vivekanandan, P.; Kundu, B.

10.1101/2020.01.30.927871 — evolutionary biology — Posted on 2020-02-02

3721 Spatial Coding in the Subiculum Requires Anterior Thalamic Inputs

Frost, B.; Cafalchio, M.; Martin, S. K.; Islam, M. N.; Aggleton, J.; O'Mara, S.

10.1101/2020.01.31.928762 — neuroscience — Posted on 2020-02-02

3722 PPanGGOLiN: Depicting microbial diversity via a Partitioned Pangenome Graph

Gautreau, G.; Bazin, A.; Gachet, M.; Planel, R.; Burlot, L.; Dubois, M.; Perrin, A.; Medigue, C.; Calteau, A.; Cruveiller, S.; Matias, C.; Ambroise, C.; Rocha, E. P. C.; Vallenet, D.

10.1101/836239 — bioinformatics — Posted on 2020-02-02

3723 Overcoming the design, build, test (DBT) bottleneck for synthesis of nonrepetitive protein-RNA binding cassettes for RNA applications

Katz, N.; Tripto, E.; Goldberg, S.; Atar, O.; Yakhini, Z.; Orenstein, Y.; Amit, R.

10.1101/2019.12.24.886168 — synthetic biology — Posted on 2020-02-02

3724 A glycogenin homolog controls Toxoplasma gondii growth via glycosylation of an E3 ubiquitin ligase

Mandalasi, M.; Kim, H. W.; Thieker, D.; Sheikh, M. O.; Gas-Pascual, E.; Rahman, K.; Zhao, P.; Daniel, N. G.; van der Wel, H.; Ichikawa, T. H.; Glushka, J. N.; Wells, L.; Woods, R. J.; Wood, Z. A.; West, C. M.

10.1101/764241 — microbiology — Posted on 2020-02-02

3725 Spreading depressions and periinfarct spreading depolarizations in the context of cortical plasticity

Jablonka, J. A.; Mhlhorn, C.; Sadowska, M. T.; Szewczyk, L. M.; Sredniawa, W.; Szlachcic, A.; Urban, P.; Winiarski, M.

10.1101/2020.01.31.927848 — neuroscience — Posted on 2020-02-01

3726 A Pathoconnectome of Early Neurodegeneration

Pfeiffer, R. L.; Anderson, J. R.; Dahal, J.; Garcia, J. C.; Yang, J.-H.; Sigulinsky, C. L.; Rapp, K.; Emrich, D. P.; Watt, C. B.; Morrison, H.; Houser, A. R.; Marc, R. E.; Jones, B. W.

10.1101/2020.01.31.929265 — neuroscience — Posted on 2020-02-01

3727 Earlier and More Robust Sensorimotor Discrimination of ASL Signs in Deaf Signers During Imitation

Quandt, L. C.; Willis, A. S.

10.1101/2020.01.31.929208 — neuroscience — Posted on 2020-02-01

3728 Systematically gap-filling the genome-scale model of CHO cells

Fouladiha, H.; Marashi, S.-A.; Li, S.; Vaziri, B.; Lewis, N. E.

10.1101/2020.01.27.921296 — systems biology — Posted on 2020-02-01

3729 Rational thoughts in neural codes

Wu, Z.; Kwon, M.; Daptardar, S.; Schrater, P. R.; Pitkow, X. S.

10.1101/765867 — neuroscience — Posted on 2020-02-01

3730 The Atlas of Inflammation-Resolution (AIR)

Serhan, C. N.; Gupta, S.; Perretti, M.; Godson, C.; Brennan, E.; Li, Y.; Soehnlein, O.; Shimizu, T.; Werz, O.; Chiurchiu, V.; Azzi, A.; Dubourdeau, M.; Smita, S.; Hoch, M.; Schopohl, P.; Khan, F.; Gjorgevikj, D.; Brauer, D.; Tripathi, A.; Cesnulevicius, K.; Lescheid, D.; Schultz, M.; Repsilber, D.; Kruse, R.; Sala, A.; Haeggstrom, J.; Levy, B. D.; Filep, J. G.; Wolkenhauer, O.

10.1101/2020.01.27.921882 — immunology — Posted on 2020-02-01

3731 The impact of global selection on local adaptation and reproductive isolation.

Bisschop, G.; Setter, D.; Rafajlovic, M.; Baird, S. J.; Lohse, K.

10.1101/855320 — evolutionary biology — Posted on 2020-02-01

3732 Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

Brook, C. E.; Boots, M.; Chandran, K.; Dobson, A. P.; Drosten, C.; Graham, A. L.; Grenfell, B.; Müller, M. A.; Ng, M.; Wang, L.-F.; van Leeuwen, A.

10.1101/696195 — ecology — Posted on 2020-02-01

3733 Interpretable detection of novel human viruses from genome sequencing data

Bartoszewicz, J. M.; Seidel, A.; Renard, B. Y.

10.1101/2020.01.29.925354 — bioinformatics — Posted on 2020-02-01

3734 Ultrafiltration Segregates Tissue Regenerative Stimuli Harboured Within and Independent of Extracellular Vesicles

Cooper, T. T.; Sherman, S. E.; Dayarathna, T.; Bell, G. I.; Ma, J.; McRae, D. M.; Lagugne-Labarthet, F.; Pasternak, S. H.; Lajoie, G. A.; Hess, D. A.

10.1101/2020.01.28.923037 — cell biology — Posted on 2020-02-01

3735 MicrographCleaner: a python package for cryo-EM micrograph cleaning using deep learning

Sanchez-Garcia, R.; Segura, J.; Maluenda, D.; Sorzano, C. O. S.; Carazo, J. M.

10.1101/677542 — bioinformatics — Posted on 2020-02-01

3736 Rats Sniff Off Toxic Air

Chen, H.; Li, X.; Yao, M.

10.1101/739003 — biochemistry — Posted on 2020-02-01

3737 Prefrontal oscillations modulate the propagation of neuronal activity required for working memory

Sherfey, J. S.; Ardid, S.; Miller, E. K.; Hasselmo, M. E.; Kopell, N. J.

10.1101/531574 — neuroscience — Posted on 2020-02-01

3738 Augmented base pairing networks encode RNA-small molecule binding preferences.

Oliver, C.; Mallet, V.; Sarrazin Gendron, R.; Reinharz, V.; Hamilton, W. L.; Moitessier, N.; Waldispuhl, J.

10.1101/701326 — bioinformatics — Posted on 2020-02-01

3739 Breaking a Strong Amide Bond: Structure and Properties of Dimethylformamidase.

Arya, C. K.; Yadav, S.; Fine, J.; Casanal, A.; Chopra, G.; Ramanathan, G.; Vinothkumar, K. R.; Subramanian, R.

10.1101/2019.12.17.879908 — biochemistry — Posted on 2020-02-01

3740 Enlarging the Scope of Randomization and Permutation Tests in Neuroimaging and Neuroscience

Maris, E.

10.1101/685560 — neuroscience — Posted on 2020-02-01

3741 Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

Trakoshis, S.; Martinez-Canada, P.; Rocchi, F.; Canella, C.; You, W.; Chakrabarti, B.; Ruigrok, A. N.; Bullmore, E.; Suckling, J.; Markicevic, M.; Zerbi, V.; MRC AIMS Consortium, ; Baron-Cohen, S.; Panzeri, S.; Gozzi, A.; Lai, M.-C.; Lombardo, M. V.

10.1101/2020.01.16.909531 — neuroscience — Posted on 2020-02-01

3742 Impact of upstream landslide on perialpine lake ecosystem: an assessment using multi-temporal satellite data

Villa, P.; Bresciani, M.; Bolpagni, R.; Braga, F.; Bellingeri, D.; Giardino, C.

10.1101/808824 — ecology — Posted on 2020-02-01

3743 Genome profiles of lymphovascular breast cancer cells reveal multiple clonally differentiated outcomes with multi-regional LCM and G&T-seq

Zhu, Z.; Wang, W.; Lin, F.; Jordan, T.; Li, G.; Silverman, S.; Qiu, S.; Joy, A. A.; Chen, C.; Hockley, D.; Zhang, X.; Zhou, Q.; Postovit, L.-M.; Zhang, X.; Hou, Y.; Mackey, J. R.; Li, B.; Wong, G. K.-S.

10.1101/807156 — cancer biology — Posted on 2020-02-01

3744 Quality control guidelines and machine learning predictions for next generation sequencing data

Albrecht, S.; Andrade-Navarro, M. A.; Fontaine, J.-F.

10.1101/768713 — bioinformatics — Posted on 2020-02-01

3745 Joint seasonality in geographic and ecological spaces, illustrated with a partially migratory bird

Basille, M.; Watling, J.; Romanach, S.; Borkhataria, R.

10.1101/514349 — ecology — Posted on 2020-02-01

3746 A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission

Flower, T. G.; Takahashi, Y.; Hudait, A.; Rose, K.; Tjahjono, N.; Pak, A.; Yokom, A. L.; Liang, X.; Wang, H.-G.; Bouamr, F.; Voth, G. A.; Hurley, J. H.

10.1101/2020.01.31.927327 — biophysics — Posted on 2020-02-01

3747 In vitro and in vivo development of the human intestine at single cell resolution

Czerwinski, M.; Holloway, E. M.; Tsai, Y.-H.; Wu, A.; Yu, Q.; Wu, J. H.; Walton, K. D.; Sweet, C.; Childs, C.; Glass, I.; Treutlein, B.; Camp, J. G.; Spence, J. R.

10.1101/2020.01.31.928788 — developmental biology — Posted on 2020-02-01

3748 Mapping metabolic oscillations during cell cycle progression

Roci, I.; Watrous, J. D.; Lagerborg, K. A.; Jain, M.; Nilsson, R.

10.1101/2020.01.31.928267 — cell biology — Posted on 2020-02-01

3749 The SensorOverlord predicts the accuracy of measurements with ratiometric biosensors

Stanley, J. A.; Johnsen, S. B.; Apfeld, J.

10.1101/2020.01.31.928895 — cell biology — Posted on 2020-02-01

3750 Immunoglobulin switch-like recombination regions implicated in the formation of extrachromosomal circular 45S rDNA involved in the maternal-specific translation system of zebrafish

Breit, T. M.; Rauwerda, H.; Pagano, J. F. B.; Ensink, W. A.; Nehrdich, U.; Spaink, H. P.; Dekker, R. J.

10.1101/2020.01.31.928739 — developmental biology — Posted on 2020-02-01

3751 Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin

Angely, C.; Ladant, D.; Planus, E.; Louis, B.; Filoche, M.; Chenal, A.; ISABEY, d.

10.1101/2020.01.31.928192 — cell biology — Posted on 2020-02-01

3752 BRAWNIN: A sORF-encoded Peptide Essential for Vertebrate Mitochondrial Complex III Assembly

Zhang, S.; Liang, C.; Mary, C.; Kerouantan, B.; Francisco, J.; Jagannathan, N. S.; Olexiouk, V.; Peh, J. H.; Tang, C.; Fidelito, G.; Nama, S.; Cheng, R.-K.; Wee, C. L.; Wang, L. C.; Roggli, P. D.; Sampath, P.; Lane, L.; Petretto, E.; Sobota, R.; Jesuthasan, S.; Sun, L.; Tucker-Kellogg, L.; Reversade, B.; Menschaert, G.; Stroud, D. A.; Ho, L.

10.1101/2020.01.31.926402 — cell biology — Posted on 2020-02-01

3753 Osh6 requires Ist2 for localization to the ER-PM contacts and efficient phosphatidylserine transport

D'Ambrosio, J. M.; Albanese, V.; Lipp, N.-F.; FLEURIOT, L.; Debayle, D.; Drin, G.; Copic, A.

10.1101/2020.01.31.928440 — cell biology — Posted on 2020-02-01

3754 Semi-supervised segmentation and genome annotation

Chan, R. C. W.; McNeil, M.; Roberts, E. G.; Mendez, M.; Libbrecht, M. W.; Hoffman, M. M.

10.1101/2020.01.30.926923 — bioinformatics — Posted on 2020-02-01

3755 Complex networks of miRNA-transcription factors mediate gene dosage compensation in aneuploid cancer

Acon, M. S.; Oviedo, G.; Baez, E.; Vasquez-Vargas, G.; Guevara-Coto, J.; Segura-Castillo, A.; Siles-Canales, F.; Quiros-Barrantes, S.; Mendes, P.; Mora-Rodriguez, R.

10.1101/2020.01.31.928507 — systems biology — Posted on 2020-02-01

3756 Xpo7 negatively regulates Hedgehog signaling by exporting Gli2 from the nucleus

Markiewicz, Łukasz; Uspienski, T.; Niedziołka, S. M.; Niewiadomski, P.

10.1101/2020.01.31.928408 — molecular biology — Posted on 2020-02-01

3757 Abnormal expression of GABAA receptor sub-units and hypomotility upon loss of gabra1 in zebrafish.

Reyes-Nava, N. G.; Yu, H.-C.; Coughlin, C. R.; Shaikh, T. H.; Quintana, A. M.

10.1101/2020.01.31.929455 — developmental biology — Posted on 2020-02-01

3758 Phase separation of toxic dipeptide repeat proteins related to C9orf72 ALS/FTD

Jafarinia, H.; van der Giessen, E.; Onck, P.

10.1101/2020.01.31.926428 — biophysics — Posted on 2020-02-01

3759 The architecture of metabolism maximizes biosynthetic diversity in the largest class of fungi

Gluck-Thaler, E.; Haridas, S.; Binder, M.; Grigoriev, I. V.; Crous, P. W.; Spatafora, J. W.; Bushley, K.; Slot, J. C.

10.1101/2020.01.31.928846 — genomics — Posted on 2020-02-01

3760 Contrasting species functional trait structuring of subarctic versus subtropical copepod communities

Garcia-Comas, C.; Hsieh, C.-h.; Chiba, S.; Sugisaki, H.; Hashioka, T.; Smith, S. L.

10.1101/2020.01.31.928705 — ecology — Posted on 2020-02-01

3761 Global reference mapping and dynamics of human transcription factor footprints

Vierstra, J.; Lazar, J.; Sandstrom, R.; Halow, J.; Lee, K.; Bates, D.; Diegel, M.; Dunn, D.; Neri, F.; Haugen, E.; Rynes, E.; Reynolds, A.; Nelson, J.; Johnson, A.; Frerker, M.; Buckley, M.; Kaul, R.; Meuleman, W.; Stamatoyannopoulos, J. A.

10.1101/2020.01.31.927798 — genomics — Posted on 2020-02-01

3762 Detecting sex-linked genes using genotyped individuals sampled in natural populations

Kafer, J.; Lartillot, N.; Marais, G. A.; Picard, F.

10.1101/2020.01.31.928291 — genomics — Posted on 2020-02-01

3763 Hierarchical modeling of haplotype effects based on a phylogeny

Selle, M. L.; Gorjanc, G.; Steinsland, I.; Lindgren, F.; Cubric Curic, V.; Brajkovic, V.

10.1101/2020.01.31.928390 — genomics — Posted on 2020-02-01

3764 A Self-Attention Model for Inferring Cooperativity between Regulatory Features

Ullah, F.; Ben-Hur, A.

10.1101/2020.01.31.927996 — genomics — Posted on 2020-02-01

3765 Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

Hillary, R. F.; Stevenson, A. J.; McCartney, D. L.; Campbell, A.; Walker, R. M.; Howard, D. M.; Ritchie, C. W.; Horvath, S.; Hayward, C.; McIntosh, A. M.; Porteous, D. J.; Deary, I. J.; Evans, K. L.; Marioni, R. E.

10.1101/2020.01.31.928648 — genomics — Posted on 2020-02-01

3766 Genomic novelty versus convergence in the basis of adaptation to whole genome duplication

Bohutinska, M.; Alston, M.; Monnahan, P.; Bray, S.; Paajanen, P.; Kolar, F.; Yant, L.

10.1101/2020.01.31.929109 — evolutionary biology — Posted on 2020-02-01

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