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Archive, 2020-07

3 RHEB/mTOR-hyperactivity causing cortical malformations drives seizures through increased axonal connectivity
Onori, M. P.; Koene, L. M. C.; Schafer, C. B.; Nellist, M.; de Brito van Velze, M.; Gao, Z.; Elgersma, Y.; van Woerden, G. M.
10.1101/2020.07.08.189399 — neuroscience — Posted on 2020-07-10
5 Protocol for Magnetic Resonance Imaging Acquisition, Quality Assurance, and Quality Check for the Accelerator Program for Discovery in Brain Disorders using Stem Cells
Parekh, P.; Bhalerao, G. V.; Rao, R.; Sreeraj, V. S.; Holla, B.; Saini, J.; Venkatasubramanian, G.; John, J. P.; Jain, S.; ADBS consortium,
10.1101/2020.07.07.191155 — neuroscience — Posted on 2020-07-10
8 Orientation of Temporal Interference for Non-Invasive Deep Brain Stimulation in Epilepsy
Missey, F.; Rusina, E.; Acerbo, E.; Botzanowski, B.; Carron, R.; Trebuchon, A.; Bartolomei, F.; Jirsa, V.; Williamson, A.
10.1101/2020.07.07.191692 — neuroscience — Posted on 2020-07-10
10 Extracting neural signals from semi-immobilized animals with deformable non-negative matrix factorization
Nejatbakhsh, A.; Varol, E.; Yemini, E.; Venkatachalam, V.; Lin, A.; Samuel, A. D. T.; Paninski, L.
10.1101/2020.07.07.192120 — neuroscience — Posted on 2020-07-10
12 Recurrent Neural Network-based Acute Concussion Classifier using Raw Resting State EEG Data
Thanjavur, K.; Babul, A.; Foran, B.; Bielecki, M.; Gilchrist, A.; Hristopulos, D. T.; Brucar, L. R.; Virji-Babul, N.
10.1101/2020.07.07.192138 — neuroscience — Posted on 2020-07-10
13 Muscle activation patterns are more constrained and regular in treadmill than in overground human locomotion
Mileti, I.; Serra, A.; Wolf, N.; Munoz-Martel, V.; Ekizos, A.; Palermo, E.; Arampatzis, A.; Santuz, A.
10.1101/2020.07.07.191080 — neuroscience — Posted on 2020-07-10
15 Creation of a novel trigeminal tractography atlas for automated trigeminal nerve identification
Zhang, F.; Xie, G.; Leung, L.; Mooney, M. A.; Epprecht, L.; Norton, I.; Rathi, Y.; Kikinis, R.; Al-Mefty, O.; Makris, N.; Golby, A. J.; ODonnell, L. J.
10.1101/2020.01.15.904938 — neuroscience — Posted on 2020-07-10
17 LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation
Pischedda, F.; Cirnaru, M. D.; Ponzoni, L.; Sandre, M.; Biosa, A.; Carrion, M. P.; Marin, O.; Morari, M.; Pan, L.; Greggio, E.; Bandopadhyay, R.; Sala, M.; Piccoli, G.
10.1101/721266 — neuroscience — Posted on 2020-07-10
18 Activation of endogenous retroviruses during brain development causes neuroinflammation
Jönsson, M. E.; Garza, R.; Sharma, Y.; Petri, R.; Södersten, E.; Johansson, J. G.; Johansson, P. A.; Atacho, D. A.; Pircs, K.; Madsen, S.; Yudovich, D.; Ramakrishnan, R.; Holmberg, J.; Larsson, J.; Jern, P.; Jakobsson, J.
10.1101/2020.07.07.191668 — neuroscience — Posted on 2020-07-10
20 Long-read assembly of a Great Dane genome highlights the contribution of GC-rich sequence and mobile elements to canine genomes
Halo, J.; Pendelton, A. L.; Shen, F.; Doucet, A. J.; Derrien, T.; Hitte, C.; Kirby, L. E.; Myers, B.; Sliwerska, E.; Emery, S.; Moran, J. V.; Boyko, A.; Kidd, J. M.
10.1101/2020.07.31.231761 — genomics — Posted on 2020-07-31
30 Anxiety and the neurobiology of temporally uncertain threat anticipation
Hur, J.; Smith, J. F.; DeYoung, K. A.; Anderson, A. S.; Kuang, J.; Kim, H. C.; Tillman, R. M.; Kuhn, M.; Fox, A. S.; Shackman, A. J.
10.1101/2020.02.25.964734 — neuroscience — Posted on 2020-07-31
31 Dopamine-gated memory selection during slow wave sleep
Isotalus, H. K.; Carr, W. J.; Averill, G. G.; Radtke, O.; Selwood, J.; Williams, R.; Ford, E.; McCullagh, L.; McErlane, J.; O'Donnell, C. K.; Durant, C.; Bartsch, U.; Jones, M. W.; Munoz-Neira, C.; Wearn, A. R.; Grogan, J. P.; Coulthard, E. J.
10.1101/2020.05.23.112375 — neuroscience — Posted on 2020-07-31
32 Different complement immune pathways mediate innate anxiety and learned fear
Westacott, L. J.; Humby, T.; Naan, N.; Brain, S. A.; Bush, E.-L.; Toneva, M.; Baloc, A.-I.; Lander, N.; Moon, A. L.; Reddaway, J.; Owen, M. J.; Hall, J.; Hughes, T. R.; Morgan, B. P.; Gray, W. P.; Wilkinson, L.
10.1101/685537 — neuroscience — Posted on 2020-07-31
36 Ebola and Marburg virus infection in bats induces a systemic response
Jayaprakash, A. D.; Ronk, A. J.; Prasad, A. N.; Covington, M. F.; Stein, K. R.; Schwarz, T. M.; Hekmaty, S.; Fenton, K. A.; Geisbert, T. W.; Basler, C. F.; Bukreyev, A.; Sachidanandam, R.
10.1101/2020.04.13.039503 — microbiology — Posted on 2020-07-31
39 Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories
Su, Y.; Chen, D.; Lausted, C.; Yuan, D.; Choi, J.; Dai, C.; Voillet, V.; Scherler, K.; Troisch, P.; Duvvuri, V. R.; Baloni, P.; Qin, G.; Smith, B.; Kornilov, S.; Rostomily, C.; Xu, A.; Li, J.; Dong, S.; Rothchild, A.; Zhou, J.; Murray, K.; Edmark, R.; Hong, S.; Jones, L.; Zhou, Y.; Roper, R.; Mackay, S.; O'Mahony, D. S.; Dale, C. R.; Wallick, J. A.; Algren, H. A.; Michael, Z. A.; Magis, A.; Wei, W.; Price, N. D.; Huang, S.; Subramanian, N.; Wang, K.; Hadlock, J.; Hood, L.; Aderem, A.; Bluestone, J. A.; Lanier, L. L.; Greenberg, P.; Gottardo, R.; Davis, M. M.; Goldman, J. D.; Heath, J. R.; the
10.1101/2020.07.27.224063 — immunology — Posted on 2020-07-31
41 Automatic segmentation of dentate nuclei for microstructure assessment: example of application to temporal lobe epilepsy patients
Gaviraghi, M.; Savini, G.; Castellazzi, G.; Palesi, F.; Rolandi, N.; Sacco, S.; Pichiecchio, A.; Mariani, V.; Tartara, E.; Tassi, L.; Vitali, P.; D'Angelo, E.; Gandini Wheeler-Kingshott, C. A. M.
10.1101/2020.07.29.222430 — bioengineering — Posted on 2020-07-31
43 Repopulating Kupffer Cells Originate Directly from Hematopoietic Stem Cells
Jiang, Y.; Fan, X.; Lu, P.; Cui, X.; Wu, P.; Lin, W.; Zhang, D.; Yuan, S.; Liu, B.; Chen, F.; You, H.; Wei, H.; He, F.; Jia, J.
10.1101/2020.07.31.230649 — cell biology — Posted on 2020-07-31
47 Whole genome assembly of Culex tarsalis
Main, B. J.; Marcantonio, M.; Johnston, S.; Rasgon, J.; Brown, C. T.; Barker, C. M.
10.1101/2020.02.17.951855 — genomics — Posted on 2020-07-31
49 Insecticide resistance status of Aedes aegypti in Bangladesh
Al-Amin, H. M.; Johora, F. T.; Irish, S. R.; Hossainey, M. R. H.; Vizcaino, L.; Paul, K. K.; Khan, W. A.; Haque, R.; Alam, M. S.; Lenhar, A.
10.1101/2020.07.31.231076 — microbiology — Posted on 2020-07-31
51 Functional specialization of human salivary glands and origins of proteins intrinsic to human saliva
Saitou, M.; Gaylord, E.; Xu, D.; May, A.; Neznanova, L.; Nathan, S.; Grawe, A.; Chang, J.; Ryan, W.; Ruhl, S.; Knox, S. M.; Gokcumen, O.
10.1101/2020.02.12.945659 — developmental biology — Posted on 2020-07-31
52 Structure of a type IV CRISPR-Cas effector complex
Zhou, Y.; Bravo, J. P. K.; Taylor, H. N.; Steens, J.; Jackson, R. N.; Staals, R. H. J.; Taylor, D. W.
10.1101/2020.07.31.231399 — biochemistry — Posted on 2020-07-31
54 Oscillatory correlates of auditory working memory examined with human electrocorticography
Kumar, S.; Gander, P. E.; Berger, J. I.; Billig, A. J.; Nourski, K. V.; Oya, H.; Kawasaki, H.; Howard, M. A.; Griffiths, T. D.
10.1101/2020.06.19.161901 — neuroscience — Posted on 2020-07-31
55 BRG1 promotes transcriptional patterns that are permissive to proliferation in cancer cells
Giles, K. A.; Gould, C. M.; Achinger-Kawecka, J.; Page, S. G.; Kafer, G.; Luu, P.-L.; Cesare, A. J.; Clark, S. J.; Taberlay, P. C.
10.1101/2020.07.03.187385 — molecular biology — Posted on 2020-07-31
57 Expression of Tim-3 drives naive Treg to an effector-like state with enhanced suppressive activity
Banerjee, H.; Nieves-Rosado, H.; Kulkarni, A.; Murter, B.; Chandran, U. R.; Chang, A.; Szymczak-Workman, A. L.; Vujanovic, L.; Ferris, R. L.; Kane, L. P.
10.1101/2020.07.31.230714 — immunology — Posted on 2020-07-31
59 A tissue-engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling
Li, H.; Bague, T.; Kirschner, A.; Weisenthal, R. W.; Patteson, A. E.; Annabi, N.; Stamer, W. D.; Ganapathy, P. S.; Herberg, S.
10.1101/2020.07.31.229229 — bioengineering — Posted on 2020-07-31
61 Expansin-controlled cell wall stiffness regulates root growth in Arabidopsis
Samalova, M.; Elsayad, K.; Melnikava, A.; Peaucelle, A.; Gahurova, E.; Gumulec, J.; Spyroglou, I.; Zemlyanskaya, E. V.; Ubogoeva, E. V.; Hejatko, J.
10.1101/2020.06.25.170969 — plant biology — Posted on 2020-07-31
62 A novel isoform of ACE2 is expressed in human nasal and bronchial respiratory epithelia and is upregulated in response to RNA respiratory virus infection
Blume, C.; Jackson, C. L.; Spalluto, C. M.; Legebeke, J.; Nazlamova, L. A.; Conforti, F.; Perotin-Collard, J.-M.; Frank, M.; Crispin, M.; Coles, J.; Thompson, J.; Ridley, R. A.; Dean, L. S.; Loxham, M.; Azim, A.; Tariq, K.; Johnston, D. A.; Skipp, P. J.; Djukanovic, R.; Baralle, D.; McCormick, C. J.; Davies, D. E.; Lucas, J. S.; Wheway, G.; Mennella, V.
10.1101/2020.07.31.230870 — molecular biology — Posted on 2020-07-31
63 Temperature alters gene expression in mosquitoes during arbovirus infection
Wimalasiri-Yapa, B. R.; Barrero, R. A.; Stassen, L.; Hafner, L. M.; McGraw, E. A.; Pyke, A. T.; Jansen, C. C.; Suhrbier, A.; Yakob, L.; Hu, W.; Devine, G. J.; Frentiu, F. D.
10.1101/2020.07.31.230425 — microbiology — Posted on 2020-07-31
66 Exaggerated in vivo IL-17 responses discriminate recall responses in active TB
Pollara, G.; Turner, C. T.; Tomlinson, G. S.; Bell, L. C.; Khan, A.; Peralta, L. F.; Folino, A.; Akarca, A.; Venturini, C.; Baker, T.; Ricciardolo, F. L.; Marafioti, T.; Ugarte-Gil, C.; Moore, D. A.; Chain, B. M.; Noursadeghi, M.
10.1101/516690 — immunology — Posted on 2020-07-31
68 Cell cycle-dependent active stress drives epithelia remodeling
Devany, J.; Sussman, D. M.; Manning, M. L.; Gardel, M. L.
10.1101/804294 — biophysics — Posted on 2020-07-31
69 Lifelong Ulk1-mediated autophagy deficiency in muscle induces mitochondrial dysfunction and contractile weakness
Nichenko, A. S.; Sorensen, J. R.; Southern, W. M.; Qualls, A. E.; Schifino, A. G.; McFaline-Figueroa, J.; Blum, J. E.; Thalacker-Mercer, A. E.; Greising, S. M.; Call, J. A.
10.1101/2020.07.31.223412 — physiology — Posted on 2020-07-31
71 Chronic pain alters microvascular architectural organization of somatosensory cortex
Zippo, A. G.; Del Grosso, V.; Patera, A.; Riccardi, M. P.; Tredici, I. G.; Bertoli, G. R.; Mittone, A.; Valente, M.; Stampanoni, M.; Coan, P.; Bravin, A.; Biella, G. M. E.
10.1101/755132 — neuroscience — Posted on 2020-07-31
73 Multiplex-GAM: genome-wide identification of chromatin contacts yields insights not captured by Hi-C
Beagrie, R. A.; Thieme, C. J.; Annunziatella, C.; Baugher, C.; Zhang, Y.; Schueler, M.; Kramer, D. C.; Chiariello, A. M.; Bianco, S.; Kukalev, A.; Li, Y.; Kempfer, R.; Scialdone, A.; Welch, L. A.; Nicodemi, M.; Pombo, A.
10.1101/2020.07.31.230284 — molecular biology — Posted on 2020-07-31
74 Disordered peptides impair neutrophil bacterial clearance and enhance tissue damage in septic patients
Timar, C. I.; Kolonics, F.; Berzsenyi, V.; Tamaska, E.; Parkanyi, A.; Merchant, M. L.; Wilkey, D. W.; Ivanyi, Z.; McLeish, K. R.; Ligeti, E.
10.1101/2020.07.31.227017 — immunology — Posted on 2020-07-31
79 Hypoxia regulates endogenous double-stranded RNA production via reduced mitochondrial DNA transcription
Arnaiz, E.; Miar, A.; Dias, A. G.; Prasad, N.; Schulze, U.; Waithe, D.; Rehwinkel, J.; Harris, A. L.
10.1101/2020.07.31.230300 — cancer biology — Posted on 2020-07-31
80 SILAC proteomics implicates the ubiquitin conjugating enzyme UBE2D in SOCS1-mediated downmodulation of the MET receptor in hepatocytes
Santharam, M. A.; Shukla, A.; Ihsan, A. U.; Cloutier, M.; Levesque, D.; Ramanathan, S.; Boisvert, F.-M.; Ilangumaran, S.
10.1101/2020.07.31.231225 — molecular biology — Posted on 2020-07-31
83 Transcriptional Atlas of Ileal-Anal Pouch Immune Cells from Ulcerative Colitis Patients
Devlin, J. C.; Axelrad, J.; Hine, A.; Chang, S.; Sarkar, S.; Lin, J.-D.; Ruggles, K. V.; Hudesman, D.; Cadwell, K.; Loke, P.
10.1101/2020.07.31.231308 — immunology — Posted on 2020-07-31
85 Diversification, disparification, and hybridization in the desert shrubs Encelia
Singhal, S.; Roddy, A.; DiVittorio, C.; Sanchez-Amaya, A.; Henriquez, C.; Brodersen, C.; Fehlberg, S.; Zapata, F.
10.1101/2020.07.31.230938 — evolutionary biology — Posted on 2020-07-31
86 The avian W chromosome is a refugium for endogenous retroviruses with likely effects on female-biased mutational load and genetic incompatibilities
Peona, V.; Palacios-Gimenez, O. M.; Blommaert, J.; Liu, J.; Haryoko, T.; Jonsson, K. A.; Irestedt, M.; Zhou, Q.; Jern, P.; Suh, A.
10.1101/2020.07.31.230854 — evolutionary biology — Posted on 2020-07-31
88 KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation
Tran, T. H.; Chan, A. H.; Young, L. C.; Bindu, L.; Neale, C.; Messing, S.; Dharmaiah, S.; Taylor, T.; Denson, J.-P.; Esposito, D.; Nissley, D. V.; Stephen, A. G.; McCormick, F.; Simanshu, D. K.
10.1101/2020.07.31.231134 — biophysics — Posted on 2020-07-31
93 Measuring reading ability in the web-browser with a lexical decision task
Yeatman, J. D.; Tang, K. A.; Donnelly, P. M.; Yablonski, M.; Ramamurthy, M.; Karipidis, I. I.; Caffarrra, S.; Takada, M. E.; Ben-Shacha, M.; Domingue, B. W.
10.1101/2020.07.30.229658 — animal behavior and cognition — Posted on 2020-07-31
95 Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior
Perich, M. G.; Conti, S.; Badi, M.; Bogaard, A.; Barra, B.; Wurth, S.; Bloch, J.; Courtine, G.; Micera, S.; Capogrosso, M.; Milekovic, T.
10.1101/2020.07.30.228767 — neuroscience — Posted on 2020-07-31
97 Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Zhou, T.; Tsybovsky, Y.; Olia, A. S.; Gorman, J.; Rapp, M. A.; Cerutti, G.; Chuang, G.-Y.; Katsamba, P. S.; Nazzari, A.; Sampson, J. M.; Schon, A.; Wang, P. D.; Bimela, J.; Shi, W.; Teng, I.-T.; Zhang, B.; Boyington, J. C.; Sastry, M.; Stephens, T.; Stuckey, J.; Wang, S.; Friesner, R. A.; Ho, D. D.; Mascola, J. R.; Shapiro, L.; Kwong, P. D.
10.1101/2020.07.04.187989 — immunology — Posted on 2020-07-31
98 Isolating Compounds that Inhibit EV 71 Virus
Murali, G.; Kejriwal, R.; Olson, D.; Alexandrescu, L.; White, S.
10.1101/2020.07.30.229815 — cell biology — Posted on 2020-07-31
100 It's not just poverty: unregulated global market and bad governance explain unceasing deforestation in Western Madagascar
Vieilledent, G.; Nourtier, M.; Grinand, C.; Pedrono, M.; Clausen, A.; Rabetrano, T.; Rakotoarijaona, J.-R.; Rakotoarivelo, B.; Rakotomalala, F. A.; Rakotomalala, L.; Razafimpahanana, A.; Ralison, J. M.; Achard, F.
10.1101/2020.07.30.229104 — ecology — Posted on 2020-07-31
106 How we pay attention in naturalistic settings
Turoman, N.; Tivadar, R.; Retsa, C.; Murray, M. M.; Matusz, P. J.
10.1101/2020.07.30.229617 — neuroscience — Posted on 2020-07-31
107 Network variants are similar between task and rest states
Kraus, B.; Perez, D.; Ladwig, Z.; Seitzman, B. A.; Dworetsky, A.; Petersen, S.; Gratton, C.
10.1101/2020.07.30.229492 — neuroscience — Posted on 2020-07-31
108 Spatially localized cluster solutions in inhibitory neural networks
Ryu, H.; Miller, J.; Teymuroglu, Z.; Wang, X.; Booth, V.; Campbell, S. A.
10.1101/2020.07.30.229542 — neuroscience — Posted on 2020-07-31
111 Genomic diversity and hotspot mutations in 30,983 SARS-CoV-2 genomes: moving toward a universal vaccine for the "confined virus"?
Alouane, T.; Laamarti, M.; Essabbar, A.; Hakmi, M.; Bouricha, E. M.; Chemao-Elfihri, M. W.; Kartti, S.; Boumajdi, N.; Bendani, H.; Laamarti, R.; Ghrifi, F.; Allam, L.; Aanniz, T.; Ouadghiri, M.; El Hafidi, N.; El Jaoudi, R.; Benrahma, H.; El Attar, J.; Mentag, R.; Sbabou, L.; Nejjari, C.; Amzazi, S.; Belyamani, L.; Ibrahimi, A.
10.1101/2020.06.20.163188 — genomics — Posted on 2020-07-31
120 SARS-CoV-2 protein subunit vaccination elicits potent neutralizing antibody responses
Mandolesi, M.; Sheward, D. J.; Hanke, L.; Ma, J.; Pushparaj, P.; Perez Vidakovics, L.; Kim, C.; Lore, K.; Castro Dopico, X.; Coquet, J. M.; McInerney, G.; Karlsson Hedestam, G. B.; Murrell, B.
10.1101/2020.07.31.228486 — immunology — Posted on 2020-07-31
123 Fitness benefit plays a vital role in the retention of the Pi-ta susceptible alleles
Liu, J.; Wang, Y.; Zhang, S.; Wu, F.; Wang, L.; Xue, J.; Zhang, Y.; Xie, P.; Hang, Y.; Sun, X.
10.1101/2020.07.30.229831 — evolutionary biology — Posted on 2020-07-31
124 Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase
Mickolajczyk, K. J.; Shelton, P. M. M.; Grasso, M.; Cao, X.; Warrington, S. R.; Aher, A.; Liu, S.; Kapoor, T. M.
10.1101/2020.07.31.231274 — biophysics — Posted on 2020-07-31
126 Pursuing the Mechanisms Underlying Alcohol-Induced Changes in the Ghrelin System: New Insights from Preclinical and Clinical Investigations
Farokhnia, M.; Deschaine, S. L.; Gregory-Flores, A.; Zallar, L. J.; You, Z.-B.; Sun, H.; Harvey, D. M.; Marchette, R. C. N.; Tunstall, B. J.; Mani, B. K.; Moose, J. E.; Lee, M. R.; Gardner, E.; Akhlaghi, F.; Roberto, M.; Hougland, J.; Zigman, J. M.; Koob, G. F.; Vendruscolo, L. F.; Leggio, L.
10.1101/2020.07.30.228494 — physiology — Posted on 2020-07-31
127 Intrinsic neural timescales related to sensory processing: Evidence from abnormal behavioural states
Zilio, F.; Gomez-Pilar, J.; Cao, S.; Zhang, J.; Zang, D.; Qi, Z.; Tan, J.; Hiromi, T.; Wu, X.; Fogel, S.; Huang, Z.; Hohmann, M. R.; Fomina, T.; Synofzik, M.; Grosse-Wentrup, M.; Owen, A. M.; Northoff, G.
10.1101/2020.07.30.229161 — neuroscience — Posted on 2020-07-31
129 SARS-CoV-2 suppresses mRNA expression of selenoproteins associated with ferroptosis, ER stress and DNA synthesis
Wang, Y.; Huang, J.; Sun, Y.; He, J.; Li, W.; Liu, Z.; Taylor, E. W.; Rayman, M. P.; Wan, X.; Zhang, J.
10.1101/2020.07.31.230243 — microbiology — Posted on 2020-07-31
130 Study on β-Chitosan against the binding of SARS-CoV-2S-RBD/ACE2
Alitongbieke, G.; Li, X.-M.; Wu, Q.-C.; Lin, Z.-C.; Huang, J.-F.; Xue, Y.; Liu, J.-N.; Lin, J.-M.; Pan, T.; Chen, Y.-X.; Su, Y.; Zhang, G.-G.; Leng, B.; Liu, S.-W.; Pan, Y.-T.
10.1101/2020.07.31.229781 — cell biology — Posted on 2020-07-31
133 A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine
Sun, W.; McCroskery, S.; Liu, W.-C.; Leist, S. R.; Liu, Y.; Albrecht, R. A.; Slamanig, S.; Oliva, J.; Amanat, F.; Schaefer, A.; Dinnon, K. H.; Innis, B. L.; Garcia-Sastre, A.; Krammer, F.; Baric, R. S.; Palese, P.
10.1101/2020.07.30.229120 — microbiology — Posted on 2020-07-31
134 Phylogenomic analysis of SARS-CoV-2 genomes from western India reveals unique linked mutations
Paul, D.; Jani, K.; Kumar, J.; Chauhan, R.; Seshadri, V.; Lal, G.; Karyakarte, R.; Joshi, S.; Tambe, M.; Sen, S.; Karade, S.; Anand, K. B.; Shergill, S. P. S.; Gupta, R. M.; Bhat, M. K.; Sahu, A.; Shouche, Y. S.
10.1101/2020.07.30.228460 — genomics — Posted on 2020-07-31
139 Midcell localization of PBP4 of Escherichia coli is essential for the timing of divisome assembly
Verheul, J.; Lodge, A.; Yau, H.; Liu, X.; Solovyova, A. S.; Typas, A.; Banzhaf, M.; Vollmer, W.; den Blaauwen, T.
10.1101/2020.07.30.230052 — microbiology — Posted on 2020-07-31
141 PHYTOCHROMES B1/B2 ARE MAJOR REGULATORS OF RIPENING-ASSOCIATED EPIGENOME REPROGRAMMING IN TOMATO FRUITS
Bianchetti, R.; Bellora, N.; de Haro, L.; Zuccarelli, R.; Rosado, D.; Freschi, L.; Rossi, M.; BERMUDEZ, L. F.
10.1101/2020.07.30.227447 — plant biology — Posted on 2020-07-31
142 The histidine phosphotransfer AHP4 plays a negative role in Arabidopsis plant response to drought
Ha, c. v.; Nguyen, K. H.; Mostofa, M. G.; Tran, C. D.; Watanabe, Y.; Li, W.; Osakabe, Y.; Sato, M.; Toyooka, K.; Tanaka, M.; Seki, M.; Burritt, D. J.; Anderson, C.; Zhang, R.; Tran, S. P.-L.
10.1101/2020.07.30.229971 — plant biology — Posted on 2020-07-31
144 MacaquePose: A novel 'in the wild' macaque monkey pose dataset for markerless motion capture
Labuguen, R.; Matsumoto, J.; Negrete, S.; Nishimaru, H.; Nishijo, H.; Takada, M.; Go, Y.; Inoue, K.-i.; Shibata, T.
10.1101/2020.07.30.229989 — neuroscience — Posted on 2020-07-31
145 Structure-function characterization of the conserved regulatory mechanism of the Escherichia coli M48 metalloprotease BepA
Bryant, J. A.; Cadby, I. T.; Chong, Z.-S.; Sevastsyanovich, Y. R.; Morris, F. C.; Cunningham, A. F.; Kritikos, G.; Meek, R. W.; Banzhaf, M.; Chng, S.-S.; Lovering, A. L.; Henderson, I. R.
10.1101/2020.07.30.230011 — microbiology — Posted on 2020-07-31
151 Smaug membraneless organelles regulate mitochondrial function
Fernandez-Alvarez, A. J.; Thomas, M. G.; Pascual, M. L.; Habif, M.; Pimentel, J.; Corbat, A. A.; Pessoa, J. P.; La Spina, P. E.; Boscaglia, L.; Plessis, A.; Carmo-Fonseca, M.; Grecco, H. E.; Casado, M.; Boccaccio, G. L.
10.1101/2020.07.31.223099 — cell biology — Posted on 2020-07-31
154 CD20 as a gatekeeper of the resting stage of human B cells
Klasener, K.; Jellusova, J.; Andrieux, G.; Salzer, U.; Boehler, C.; Steiner, S. N.; Albinus, J. B.; Cavallari, M. F.; Suess, B.; Boerries, M.; Voll, R. E.; Wollscheid, B.; Reth, M.
10.1101/2020.07.31.230110 — immunology — Posted on 2020-07-31
157 A collaborative resource platform for non-human primate neuroimaging
Messinger, A.; Sirmpilatze, N.; Heuer, K.; Loh, K. K.; Mars, R.; Sein, J.; Xu, T.; Glen, D.; Jung, B.; Seidlitz, J.; Taylor, P.; Toro, R.; Garza-Villareal, E.; Sponheim, C.; Wang, X.; Benn, A.; Cagna, B.; Dadarwal, R.; Evrard, H.; Garcia-Saldivar, P.; Giavasis, S.; Hartig, R.; Lepage, C.; Liu, C.; Majka, P.; Merchant, H.; Milham, M.; Rosa, M.; Tasserie, J.; Uhrig, L.; Margulies, D.; Klink, P. C.
10.1101/2020.07.31.230185 — neuroscience — Posted on 2020-07-31
161 The deep and slow breathing characterizing rest favors brain respiratory-drive
Girin, B.; Juventin, M.; Garcia, S.; Lefevre, L.; Amat, C.; Fourcaud-Trocme, N.; Buonviso, N.
10.1101/2020.07.30.226563 — neuroscience — Posted on 2020-07-31
163 Deep Learning Based Segmentation of Brain Tissue from Diffusion MRI
Zhang, F.; Breger, A.; Cho, K. I. K.; Ning, L.; Westin, C.-F.; O'Donnell, L. J.; Pasternak, O.
10.1101/2020.07.30.228809 — neuroscience — Posted on 2020-07-31
165 Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease
Smyth, L. J.; Kilner, J.; Nair, V.; Liu, H.; Brennan, E.; Kerr, K.; Sandholm, N.; Cole, J.; Dahlstrom, E.; Syreeni, A.; Salem, R. M.; Nelson, R. G.; Looker, H. C.; Wooster, C.; Anderson, K.; McKay, G.; Kee, F.; Young, I.; NICOLA Collaborative Team, ; Warren 3 and Genetics of Kidneys in Diabetes (GoKinD) Study Group, ; Andrews, D.; Forsblom, C.; Hirschhorn, J. N.; Godson, C.; Groop, P.-H.; Maxwell, A. P.; Susztak, K.; Kretzler, M.; Florez, J. C.; McKnight, A. J.; GENIE consortium,
10.1101/2020.07.30.228734 — molecular biology — Posted on 2020-07-31
168 Genetic determinants of wheat resistance to common root rot (spot blotch) and Fusarium crown rot
Su, J.; Zhao, J.; Zhao, S.; Shang, X.; Pang, S.; Chen, S.; Liu, D.; Kang, Z.; Wang, X.
10.1101/2020.07.30.228932 — genetics — Posted on 2020-07-31
170 Genetic variation in dispersal plasticity in an aquatic host-parasite model system
Zilio, G.; Noergaard, L. S.; Petrucci, G.; Zeballos, N.; Gougat-Barbera, C.; Kaltz, O.
10.1101/2020.07.30.228742 — evolutionary biology — Posted on 2020-07-31
172 Developing methods for measuring national distributions and densities of wild mammals using camera traps: A Kosovo study
Beatham, S. E.; Ward, A. I.; Fouracre, D.; Wilsmore, A. J.; Zogu, B.; Sallmann, M.; Muhaxhiri, J.; Smith, G. C.; Gjinovci, V.
10.1101/2020.07.30.193078 — ecology — Posted on 2020-07-31
173 Trophic niche of the invasive gregarious species Crepidula fornicata, in relation to ontogenic changes
Androuin, T.; Dubois, S. F.; Hubas, C.; Lefebvre, G.; Le Grand, F.; Schaal, G.; Carlier, A.
10.1101/2020.07.30.229021 — ecology — Posted on 2020-07-31
174 Automated prediction of the clinical impact of structural copy number variations
Gaziova, M.; Pos, O.; Krampl, W.; Kubiritova, Z.; Kucharik, M.; Radvanszky, J.; Budis, J.; Szemes, T.
10.1101/2020.07.30.228601 — bioinformatics — Posted on 2020-07-31
177 Deep learning-enhanced light-field imaging with continuous validation
Wagner, N.; Beuttenmueller, F.; Norlin, N.; Gierten, J.; Wittbrodt, J.; Weigert, M.; Hufnagel, L.; Prevedel, R.; Kreshuk, A.
10.1101/2020.07.30.228924 — bioengineering — Posted on 2020-07-31
181 Gene expression evolution in pattern-triggered immunity within Arabidopsis thaliana and across Brassicaceae species
Winkelmüller, T. M.; Entila, F.; Anver, S.; Piasecka, A.; Song, B.; Dahms, E.; Sakakibara, H.; Gan, X.; Kułak, K.; Sawikowska, A.; Krajewski, P.; Tsiantis, M.; Garrido-Oter, R.; Fukushima, K.; Schulze-Lefert, P.; Laurent, S.; Bednarek, P.; Tsuda, K.
10.1101/2020.07.29.227397 — plant biology — Posted on 2020-07-31
182 Mitochondrial state determines functionally divergent stem cell population in planaria
Mohamed Haroon, M.; Lakshmanan, V.; Sarkar, S. R.; Lei, K.; Vemula, P. K.; Palakodeti, D.
10.1101/2020.07.29.226365 — cell biology — Posted on 2020-07-31
183 Polyunsaturated phospholipids increase cell resilience to mechanical constraints
Ferreira, T.; Kadri, L.; Bacle, A.; Khoury, S.; Vandebrouck, C.; Bescond, J.; Faivre, J.-F.; Sebille, S.
10.1101/2020.07.29.226746 — cell biology — Posted on 2020-07-31
184 The final step of 40S ribosomal subunit maturation is controlled by a dual key lock
Plassart, L.; Shayan, R.; Montellese, C.; Rinaldi, D.; Larburu, N.; Pichereaux, C.; Lebaron, S.; O'Donohue, M.-F.; Kutay, U.; Marcoux, J.; Gleizes, P.-E.; Plisson-Chastang, C.
10.1101/2020.07.29.226936 — molecular biology — Posted on 2020-07-31
185 Glycine Rich Segments Adopt Polyproline II Helices Which May Contribute to Biomolecular Condensate Formation
Mompean, M.; McAvan, B. S.; Felix, S. S.; Trevino, M.; Oroz, J.; Pantoja-Uceda, D.; Cabrita, E. J.; Doig, A. J.; Laurents, D. V.
10.1101/2020.07.30.229062 — biophysics — Posted on 2020-07-31
186 Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina
Li, S.; Hu, Y.; Li, Y.; Hu, M.; Wang, W.; Ma, Y.; Cai, Y.; Wei, M.; Yao, Y.; Wang, Y.; Dong, K.; Gu, Y.; Zhao, H.; Bao, J.; Qiu, Z.; Zhang, M.; Hu, X.; Xue, T.
10.1101/2020.07.29.226787 — neuroscience — Posted on 2020-07-31
188 Nuclear pores constrict upon energy depletion
Zimmerli, C. E.; Allegretti, M.; Rantos, V.; Goetz, S. K.; Obarska-Kosinska, A.; Zagoriy, I.; Halavatyi, A.; Mahamid, J.; Kosinski, J.; Beck, M.
10.1101/2020.07.30.228585 — cell biology — Posted on 2020-07-31
190 Adaptation of spontaneous activity in the developing visual cortex
Wosniack, M. E.; Kirchner, J. H.; Chao, L.-Y.; Zabouri, N.; Lohmann, C.; Gjorgjieva, J.
10.1101/2020.07.30.229559 — neuroscience — Posted on 2020-07-31
192 Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development
Pilaz, L.-J.; Joshi, K.; Liu, J.; Tsunekawa, Y.; Alsina, F.; Sethi, S.; Suzuki, I.; Vanderhaeghen, P.; Polleux, F.; Silver, D.
10.1101/2020.07.30.229724 — neuroscience — Posted on 2020-07-31
195 Genetically-encoded fluorescent biosensor for rapid detection of protein expression
Eason, M. G.; Pandelieva, A. T.; Mayer, M. M.; Khan, S. T.; Garcia, H. G.; Chica, R. A.
10.1101/2020.07.30.229633 — synthetic biology — Posted on 2020-07-30
196 Thalamic encoding of lexical status is lateralized during reading aloud
Wang, D.; Lipski, W.; Bush, A.; Chrabaszcz, A.; Dastolfo-Hromack, C.; Dickey, M. W.; Fiez, J.; Richardson, R. M.
10.1101/2020.07.30.229898 — neuroscience — Posted on 2020-07-30
197 Helicase-Like Functions in Phosphate Loop Containing Beta-Alpha Polypeptides
Vyas, P.; Trofimyuk, O.; Longo, L. M.; Deshmukh, F. K.; Sharon, M.; Tawfik, D. S.
10.1101/2020.07.30.228619 — molecular biology — Posted on 2020-07-30
199 Common variants contribute to intrinsic functional architecture of human brain
Zhao, B.; Li, T.; Smith, S. M.; Xiong, D.; Wang, X.; Yang, Y.; Luo, T.; Zhu, Z.; Shan, Y.; Hauberg, M. E.; Bendl, J.; Fullard, J. F.; Roussos, P.; Lin, W.; Li, Y.; Stein, J. L.; Zhu, H.
10.1101/2020.07.30.229914 — genetics — Posted on 2020-07-30
201 PTPN11/SHP2 negatively regulates growth in breast epithelial cells: implications on tumorigenesis
Chakladar, M.; Nair, M.; Prabhu, J.; Sridhar, T.; Kelkar, D.; Kulkarni, M.; SHASHIDHARA, L.
10.1101/2020.07.30.228445 — cancer biology — Posted on 2020-07-30
203 Constitutive androstane receptor directs T cell adaptation to bile acids in the small intestine
Chen, M. L.; Huang, X.; Wang, H.; Liu, Y.; Shang, J.; Eliason, A.; Hegner, C.; Park, H.; Frey, B.; Wang, G.; Kojetin, D. J.; Weaver, C. T.; Pipkin, M. E.; Moore, D. D.; Sundrud, M. S.
10.1101/2020.07.30.229864 — immunology — Posted on 2020-07-30
205 Perception of and anxiety about COVID-19 infection and risk behaviors for spreading infection: An international comparison
Shiina, A.; Niitsu, T.; Kobori, O.; Idemoto, K.; Hashimoto, T.; Sasaki, T.; Igarashi, Y.; Shimizu, E.; Nakazato, M.; Hashimoto, K.; Iyo, M.
10.1101/2020.07.30.228643 — scientific communication and education — Posted on 2020-07-30
206 Developmental constraints modulate reproductive fate and plasticity within the Arabidopsis ovule primordium
Hernandez-Lagana, E.; Mosca, G.; Mendocilla Sato, E.; Pires, N.; Frey, A.; Giraldo-Fonseca, A.; Grossniklaus, U.; Hamant, O.; Godin, C.; Boudaoud, A.; Grimanelli, D.; Autran, D.; Baroux, C.
10.1101/2020.07.30.226670 — plant biology — Posted on 2020-07-30
210 Natural food intake patterns do not synchronize peripheral clocks
Xie, X.; Kukino, A.; Calcagno, H. E.; Berman, A.; Garner, J. P.; Butler, M. P.
10.1101/2020.07.28.220509 — physiology — Posted on 2020-07-30
213 Heritability of individualized cortical network topography
Anderson, K. M.; Ge, T.; Kong, R.; Patrick, L. M.; Spreng, R. N.; Sabuncu, M. R.; Yeo, B. T. T.; Holmes, A.
10.1101/2020.07.30.229427 — neuroscience — Posted on 2020-07-30
214 Fluent speech: neural basis of sensorimotor plasticity in developmental stuttering
Korzeczek, A.; Primassin, A.; Wolff von Gudenberg, A.; Dechent, P.; Paulus, W.; Sommer, M.; Neef, N. E.
10.1101/2020.07.27.219360 — neuroscience — Posted on 2020-07-30
219 Unraveling nanotopography of cell surface receptors
Franke, C.; Chum, T.; Kvicalova, Z.; Glatzova, D.; Rodriguez, A.; Helmerich, D.; Frank, O.; Brdicka, T.; van de Linde, S.; Cebecauer, M.
10.1101/2019.12.23.884460 — cell biology — Posted on 2020-07-30
222 Post-prediction inference
Wang, S.; McCormick, T. H.; Leek, J. T.
10.1101/2020.01.21.914002 — bioinformatics — Posted on 2020-07-30
224 Toward an early diagnostic marker of Parkinson's: measuring iron in dopaminergic neurons with MR relaxometry
Brammerloh, M.; Morawski, M.; Weigelt, I.; Reinert, T.; Lange, C.; Pelicon, P.; Vavpetic, P.; Jankuhn, S.; Jaeger, C.; Alkemade, A.; Balesar, R.; Pine, K.; Gavriilidis, F.; Trampel, R.; Reimer, E.; Arendt, T.; Weiskopf, N.; Kirilina, E.
10.1101/2020.07.01.170563 — neuroscience — Posted on 2020-07-30
225 Small-hairpin RNAs cause target-independent microRNA dysregulation in neurons and elicit global transcriptomic changes
Kohen, R.; Baldwin, K. T.; Garay, P. M.; Tsukahara, T.; Chen, A.; Flynn, C. G.; Johnson, C.; Zhao, X.; Sutton, M. A.; Iwase, S.; Giger, R. J.
10.1101/2020.07.30.229443 — neuroscience — Posted on 2020-07-30
228 Neural correlates of the shamanic state of consciousness
Huels, E. R.; Kim, H.; Lee, U.; Bel-Bahar, T.; Colmenero, A.; Nelson, A.; Blain-Moraes, S.; Mashour, G. A.; Harris, R. E.
10.1101/2020.07.20.212522 — neuroscience — Posted on 2020-07-30
231 Genetic signatures for lineage/sublineage classification of HPV16, 18, 52 and 58 variants
Ou, Z.; Chen, Z.; Zhao, Y.; Lu, H.; Liu, W.; Li, W.; Geng, C.; Hu, G.; Wang, X.; Ren, P.; Liu, N.; Zhu, S.; Lu, L.; Li, J.
10.1101/2020.07.30.229112 — evolutionary biology — Posted on 2020-07-30
234 The ectomycorrhizal community of urban linden trees in Gdansk, Poland
Olchowik, J.; Suchocka, M.; Jankowski, P.; Malewski, T.; Hilszczanska, D.
10.1101/2020.07.30.228668 — ecology — Posted on 2020-07-30
235 Zinc Metabolic Defect of Aging Alveolar Progenitors in Progressive Pulmonary Fibrosis
Liang, J.; Huang, G.; Liu, X.; Taghavifar, F.; Liu, N.; Wang, Y.; Deng, N.; Yao, C.; Burman, A.; Xie, T.; Rowan, S.; Weigt, S. S.; BELPERIO, J.; Stripp, B.; Parks, W.; Jiang, D.; Noble, P.
10.1101/2020.07.30.229567 — cell biology — Posted on 2020-07-30
238 Quantitative sub-cellular acyl-CoA analysis reveals distinct nuclear regulation
Trefely, S.; Huber, K.; Liu, J.; Singh, J.; Doan, M.; Lovell, C. D.; Noji, M.; von Krusenstiern, E.; Jiang, H.; Bostwick, A.; Izzo, L.; Zhao, S.; Bedi, K. C.; Rame, J. E.; Bogner-Strauss, J. G.; Mesaros, C.; Wellen, K. E.; Snyder, N. W.
10.1101/2020.07.30.229468 — biochemistry — Posted on 2020-07-30
239 Single-cell morphometrics reveals ancestral principles of notochord development
Andrews, T. G.; Ponisch, W.; Paluch, E. K.; Steventon, B.; Benito-Gutierrez, E.
10.1101/2020.07.08.193813 — developmental biology — Posted on 2020-07-30
240 Lipid membranes from naked mole-rat brain lipids are cholesterol-rich, highly phase-separated, and sensitive to amyloid-induced damage
FRANKEL, D.; St John Smith, E.; Rankin, K.; Cenac, N.; Davies, M.; Kumita, J. R.; Vendruscolo, M.; Kulaberoglu, Y.; Urriola Munoz, P.; Bertrand-michel, J.; Pergande, M. R.; Preet, S.; Park, T.; Smith, A.; Bhushan, B.; Cologna, S.
10.1101/2020.06.05.134973 — biophysics — Posted on 2020-07-30
247 APOBEC2 binds Chromatin and Represses Transcription during Myoblast Differentiation
Lorenzo, J. P.; Molla, L.; Ibarra, I. L.; Ruf, S.; Subramani, P. G.; Boulais, J.; Harjanto, D.; Vonica, A.; Di Noia, J. M.; Dieterich, C.; Zaugg, J. B.; Papavasiliou, F. N.
10.1101/2020.07.29.223594 — molecular biology — Posted on 2020-07-30
249 Postnatal expansion, maturation and functionality of MR1 T cells in humans
Swarbrick, G. M.; Gela, A.; Cansler, M. E.; Null, M. D.; Duncan, R. B.; Nemes, E.; Shey, M.; Nsereko, M.; Mayanja-Kizza, H.; Kiguli, S.; Koh, J.; Hanekom, W.; Hatherill, M.; Lancioni, C.; Lewinsohn, D. M.; Scriba, T.; Lewinsohn, D. A.
10.1101/2019.12.20.882746 — immunology — Posted on 2020-07-30
251 Mitochondrial STAT3 regulates proliferation of tissue stem cells.
Peron, M.; Meneghetti, G.; Dinarello, A.; Betto, R. M.; Facchinello, N.; Tiso, N.; Martello, G.; Argenton, F.
10.1101/2020.07.17.208264 — developmental biology — Posted on 2020-07-30
255 Fine tuning of hormonal signaling is linked to dormancy status in sweet cherry flower buds
Vimont, N.; Schwarzenberg, A.; Domijan, M.; Donkpegan, A. S. L.; Beauvieux, R.; Le Dantec, L.; Arkoun, M.; Jamois, F.; Yvin, J.-C.; Wigge, P. A.; Dirlewanger, E.; Cortijo, S.; Wenden, B.
10.1101/423871 — plant biology — Posted on 2020-07-30
256 Dystrophic microglia are a disease associated microglia morphology in the human brain
Shahidehpour, R. K.; Higdon, R. E.; Crawford, N. G.; Neltner, J. H.; Ighodaro, E. T.; Patel, E.; Price, D.; Nelson, P. T.; Bachstetter, A. D.
10.1101/2020.07.30.228999 — neuroscience — Posted on 2020-07-30
259 Base-edited CAR T Cells for combinational therapy against T cell malignancies
Georgiadis, C.; Rasaiyaah, J.; Gkazi, S. A.; Preece, R.; Etuk, A.; Christi, A.; Qasim, W.
10.1101/2020.07.30.228429 — molecular biology — Posted on 2020-07-30
260 A Multi-Phenotype System to Discover Therapies for Age-Related Dysregulation of the Immune Response to Viral Infections
White, B. W.; Komalo, B.; Nicolaisen, L.; Donne, M.; Marsh, C.; DeVay, R. M.; Nguyen, A. M.; Cousin, W.; Heinrich, J.; Van Trump, W. J.; Plott, T.; Fuller, C. J.; Nguyen, D.; Chen, D.; Bucher, D.; Tyrra, S.; Haynes, L.; Kuchel, G.; Goronzy, J.; Larbi, A.; Fulop, T.; Heiser, D.; Schwandner, R.; Elabd, C.; Kamens, B.
10.1101/2020.07.30.223875 — immunology — Posted on 2020-07-30
262 Common variants associated with OSMR expression contribute to carotid plaque vulnerability, but not to cardiovascular disease in humans
van Keulen, D.; van Koeverden, I. D.; Boltjes, A.; Princen, H. M. G.; van Gool, A. J.; de Borst, G. J.; Asselbergs, F. W.; Tempel, D.; Pasterkamp, G.; van der Laan, S. W.
10.1101/576793 — genetics — Posted on 2020-07-30
263 Deaf intermarriage does not increase the prevalence of deafness alleles
Braun, D. C.; Jain, S.; Epstein, E.; Greenwald, B. H.; Herold, B.; Gray, M.
10.1101/2020.04.09.034728 — genetics — Posted on 2020-07-30
268 Direct Antimicrobial Resistance Prediction from MALDI-TOF mass spectra profile in clinical isolates through Machine Learning
Weis, C.; Cuenod, A.; Rieck, B.; Llinares-Lopez, F.; Dubuis, O.; Graf, S.; Lang, C.; Oberle, M.; Soegaard, K. K.; Osthoff, M.; Borgwardt, K.; Egli, A.
10.1101/2020.07.30.228411 — microbiology — Posted on 2020-07-30
269 Impact of low-frequency coding variants on human facial shape
Liu, D.; Alhazmi, N.; Matthews, H.; Lee, M. K.; Li, J.; Hecht, J. T.; Wehby, G. L.; Moreno, L. M.; Heike, C. L.; Roosenboom, J.; Feingold, E.; Marazita, M. L.; Claes, P.; Liao, E. C.; Weinberg, S. M.; Shaffer, J. R.
10.1101/2020.07.30.227769 — genetics — Posted on 2020-07-30
270 Biomaterial encapsulation of human mesenchymal stromal cells modulates paracrine signaling response and enhances efficacy for treatment of established osteoarthritis
McKinney, J. M.; Pucha, K. A.; Doan, T. N.; Wang, L.; Weinstock, L. D.; Tignor, B. T.; Fowle, K. L.; Levit, R. D.; Wood, L. B.; Willett, N. J.
10.1101/2020.07.30.228288 — bioengineering — Posted on 2020-07-30
271 Structural Insights into Photoactivation of Plant Cryptochrome-2
Palayam, M.; Ganapathy, J.; Guercio, A. M.; Tal, L.; Deck, S. L.; Shabek, N.
10.1101/2020.07.30.227371 — biochemistry — Posted on 2020-07-30
272 Single-Cell Transcriptomics Identifies Dysregulated Metabolic Programs of Aging Alveolar Progenitor Cells in Lung Fibrosis
Liang, J.; Huang, G.; Liu, X.; Taghavifar, F.; Liu, N.; Yao, C.; Deng, N.; Wangy, Y.; Burman, A.; Xie, T.; Rowan, S. C.; Chen, P.; Hogaboam, C. M.; Stripp, B.; Weigt, S. S.; Belperio, J.; Park, W.; Noble, P. W.; Jiang, D.
10.1101/2020.07.30.227892 — cell biology — Posted on 2020-07-30
273 Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2
Bates, T. A.; Weinstein, J. B.; Farley, S. E.; Leier, H. C.; Messer, W. B.; Tafesse, F. G.
10.1101/2020.07.30.229377 — immunology — Posted on 2020-07-30
274 Circulating Mitochondrial DNA is an Early Indicator of Severe Illness and Mortality from COVID-19
Scozzi, D.; Cano, M.; MA, L.; Zhou, D.; Zhu, J. H.; O'Halloran, J. A.; Goss, C.; Rauseo, A.; Liu, Z.; Peritore, V.; Rocco, M.; Ricci, A.; Amodeo, R.; Aimati, L.; Ibrahim, M.; Hachem, R.; Kreisel, D.; Mudd, P. A.; Kulkarni, H. S.; Gelman, A. E.
10.1101/2020.07.30.227553 — immunology — Posted on 2020-07-30
275 Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
Bos, R.; Rutten, L.; van der Lubbe, J. E. M.; Bakkers, M. J. G.; Hardenberg, G.; Wegmann, F.; Zuijdgeest, D.; de Wilde, A. H.; Koornneef, A.; Verwilligen, A.; van Manen, D.; Kwaks, T.; Vogels, R.; Dalebout, T. J.; Myeni, S. K.; Kikkert, M.; Snijder, E. J.; Li, Z.; Barouch, D. H.; Jort, V.; Langedijk, J. P.; Zahn, R. C.; Custers, J.; Schuitemaker, H.
10.1101/2020.07.30.227470 — immunology — Posted on 2020-07-30
276 Transcriptomic signatures of ageing vary in solitary and social forms of an orchid bee
Seguret, A. C.; Stolle, E.; Fleites-Ayil, F. A.; Quezada-Euan, J. J. G.; Hartfelder, K.; Meusemann, K.; Harrison, M.; Soro, A.; Paxton, R. J.
10.1101/2020.07.30.228304 — evolutionary biology — Posted on 2020-07-30
277 Single neurons throughout human memory regions phase-lock to hippocampal theta
Schonhaut, D. R.; Ramayya, A. G.; Solomon, E. A.; Herweg, N. A.; Fried, I.; Kahana, M. J.
10.1101/2020.06.30.180174 — neuroscience — Posted on 2020-07-30
278 A dynamic regulatory interface on SARS-CoV-2 RNA polymerase
Shi, W.; Chen, M.; Yang, Y.; Zhou, W.; Chen, S.; Hu, Y.; Liu, B.
10.1101/2020.07.30.229187 — molecular biology — Posted on 2020-07-30
279 The genetic variant analyses of SARS-CoV-2 strains; circulating in Bangladesh.
Mahmud, A. S. M.; Taznin, T.; Sarkar, M. M. H.; Uzzaman, M. S.; Osman, E.; Habib, M. A.; Akter, S.; Banu, T. A.; Goswami, B.; Jahan, I.; Hossain, M. S.; Khan, M. S.
10.1101/2020.07.29.226555 — genomics — Posted on 2020-07-30
282 Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike
Prevost, J.; Gasser, R.; Beaudoin-Bussieres, G.; Richard, J.; Duerr, R.; Laumaea, A.; Anand, S. P.; Goyette, G.; Benlarbi, M.; Ding, S.; Medjahed, H.; Lewin, A.; Perreault, J.; Tremblay, T.; Gendron-Lepage, G.; Gauthier, N.; Carrier, M.; Marcoux, D.; Piche, A.; Lavoie, M.; Benoit, A.; Loungnarath, V.; Brochu, G.; Haddad, E.; Stacey, H. D.; Miller, M. S.; Desforges, M.; Talbot, P. J.; Gould Maule, G. T.; Cote, M.; Therrien, C.; Serhir, B.; Bazin, R.; Roger, M.; Finzi, A.
10.1101/2020.06.08.140244 — microbiology — Posted on 2020-07-30
283 Protoporphyrin IX and verteporfin prevent SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2
Gu, C.; Wu, Y.; Guo, H.; Zhu, Y.; Xu, W.; Wang, Y.; Zhou, Y.; Sun, Z.; Cai, X.; Li, Y.; Liu, J.; Huang, Z.; Yuan, Z.; Zhang, R.; Deng, Q.; Qu, D.; Xie, Y.
10.1101/2020.04.30.071290 — microbiology — Posted on 2020-07-30
286 Whole genome sequencing based differentiation between re-infection and relapse in Indian patients with tuberculosis recurrence, with and without HIV co-infection
Shanmugam, S.; Bachmann, N. L.; Martinez, E.; Menon, R.; Narendran, G.; Narayanan, S.; Devi, K. R. U.; Sawleshwarkar, S.; Marais, B.; Sintchenko, V.
10.1101/2020.07.29.227926 — genomics — Posted on 2020-07-30
288 Cold sensitivity of the SARS-CoV-2 spike ectodomain
Edwards, R. J.; Mansouri, K.; Stalls, V.; Manne, K.; Watts, B.; Parks, R.; Gobeil, S. M. C.; Janowska, K.; Li, D.; Lu, X.; Deyton, M.; Sprenz, J.; Williams, W.; Saunders, K.; Sempowski, G. D.; Henderson, R.; Alam, M.; Haynes, B. F.; Acharya, P.
10.1101/2020.07.12.199588 — biochemistry — Posted on 2020-07-30
289 Natural selection in the evolution of SARS-CoV-2 in bats, not humans, created a highly capable human pathogen
MacLean, O. A.; Lytras, S.; Weaver, S.; Singer, J. B.; Boni, M. F.; Lemey, P.; Kosakovsky Pond, S. L.; Robertson, D. L.
10.1101/2020.05.28.122366 — evolutionary biology — Posted on 2020-07-30
292 Substrate specificity of SARS-CoV-2 nsp10-nsp16 methyltransferase
Benoni, R.; Krafcikova, P.; Baranowski, M.; Kowalska, J.; Boura, E.; Cahova, H.
10.1101/2020.07.30.228478 — molecular biology — Posted on 2020-07-30
293 Immuno-informatics Design of a Multimeric Epitope Peptide Based Vaccine Targeting SARS-CoV-2 Spike Glycoprotein
Chukwudozie, O. S.; Gray, C. M.; Fagbayi, T. A.; Chukwuanukwu, R. C.; Oyebanji, V. O.; Bankole, T. T.; Adewole, R. A.; Eze, D. M.
10.1101/2020.07.30.228221 — immunology — Posted on 2020-07-30
294 EUAdb: a resource for COVID-19 test development
Woronik, A.; Shaffer, H. W.; Kiontke, K.; Laurent, J. M.; Zambrano, R.; Boeke, J. D.; Fitch, D. H. A.
10.1101/2020.07.30.228890 — bioinformatics — Posted on 2020-07-30
295 Mucin-type O-glycosylation Landscapes of SARS-CoV-2 Spike Proteins
Zhang, Y.; Zhao, W.; Mao, Y.; Chen, Y.; Hu, L.; Zhu, J.; Gong, M.; Cheng, J.; Yang, H.
10.1101/2020.07.29.227785 — biochemistry — Posted on 2020-07-30
296 SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors
Gao, C.; Zeng, J.; Jia, N.; Stavenhagen, K.; Matsumoto, Y.; Zhang, H.; Li, J.; Hume, A. J.; Muehlberger, E.; van Die, I.; Kwan, J.; Tantisira, K.; Emili, A.; Cummings, R. D.
10.1101/2020.07.29.227462 — biochemistry — Posted on 2020-07-30
298 A Next Generation Bivalent Human Ad5 COVID-19 Vaccine Delivering Both Spike and Nucleocapsid Antigens Elicits Th1 Dominant CD4+, CD8+ T-cell and Neutralizing Antibody Responses
Rice, A.; Verma, M.; Shin, A.; Zakin, L.; Sieling, P.; Tanaka, S.; Adisetiyo, H.; Taft, J.; Patel, R. S.; Buta, S.; Martin-Fernandez, M.; Morimoto, B.; Gabitzsch, E.; Safrit, J. T.; Balint, J.; Dinkins, K.; Spilman, P.; Bogunovic, D.; Rabizadeh, S.; Niazi, K.; Soon-Shiong, P.
10.1101/2020.07.29.227595 — immunology — Posted on 2020-07-30
300 INTERMEDIUM-C mediates the shade-induced bud growth arrest in barley
Wang, H.; Seiler, C.; Sreenivasulu, N.; von Wiren, N.; Kuhlmann, M.
10.1101/2020.07.30.228510 — plant biology — Posted on 2020-07-30
303 Cone-shaped HIV-1 capsids are transported through intact nuclear pores
Zila, V.; Margiotta, E.; Turonova, B.; Müller, T. G.; Zimmerli, C. E.; Mattei, S.; Allegretti, M.; Börner, K.; Rada, J.; Müller, B.; Lusic, M.; Kräusslich, H.-G.; Beck, M.
10.1101/2020.07.30.193524 — microbiology — Posted on 2020-07-30
308 Biochemical Patterns of Antibody Polyreactivity Revealed Through a Bioinformatics-Based Analysis of CDR Loops
Boughter, C. T.; Borowska, M. T.; Guthmiller, J. J.; Bendelac, A.; Wilson, P.; Roux, B.; Adams, E. J.
10.1101/2020.07.30.229013 — immunology — Posted on 2020-07-30
309 Computational Properties of the Visual Microcircuit
Hahn, G.; Kumar, A.; Schmidt, H.; Knoesche, T.; Deco, G.
10.1101/2020.07.30.229435 — neuroscience — Posted on 2020-07-30
310 A new model of chronic Mycobacterium abscessus lung infection in immunocompetent mice
Riva, C.; Tortoli, E.; Cugnata, F.; Sanvito, F.; Esposito, A.; Rossi, M.; Colarieti, A.; Canu, T.; Cigana, C.; Bragonzi, A.; Lore', N. I.; Miotto, P.; Cirillo, D. M.
10.1101/2020.07.30.228247 — microbiology — Posted on 2020-07-30
311 Riluzole suppresses growth and enhances response to endocrine therapy in ER+ breast cancer
Stires, H.; Olukoya, A. O.; Ma, S.; Persaud, S.; Guerra, Y.; Cruz, M. I.; Benitez, C.; Rozeboom, A.; Ceuleers, H.; Berry, D. L.; Jacobsen, B. M.; Raj, G. V.; Riggins, R. B.
10.1101/2020.07.30.227561 — cancer biology — Posted on 2020-07-30
312 Biofabrication using maize protein: 3D printing using zein formulations
Tavares-Negrete, J. A.; Aceves-Colin, A. E.; Rivera-Flores, D. C.; Diaz-Armas, G. G.; Mertgen, A.-S.; Trinidad-Calderon, P. A.; Olmos-Cordero, J. M.; Gomez-Lopez, E. G.; Perez-Carrillo, E.; Escobedo-Avellaneda, Z. J.; Tamayol, A.; Alvarez, M. M.; Trujillo-de Santiago, G.
10.1101/2020.07.29.227744 — bioengineering — Posted on 2020-07-30
316 Distinct dopamine circuits transmit the reinforcing and anxiogenic effects of nicotine
Nguyen, C.; Mondoloni, S.; Centeno, I.; Durand, R.; Tolu, S.; Valverde, S.; Le Borgne, T.; Hanesse, B.; Pons, S.; Maskos, U.; Dalkara, D.; Hardelin, J.-P.; Mourot, A.; Marti, F.; Faure, P.
10.1101/2020.07.30.228189 — neuroscience — Posted on 2020-07-30
320 In-vivo evaluation of the anti-diarrheal effect of Lactococcus lactis subspecies lactis and Lactococcus piscium isolated from yogurt.
Mahmud, A. S. M.; Chowdhury, M.; Akter, R.; Islam, S.; Mazumdar, S.; Taznin, T.; Chowdhury, R.; Talukder, H.; Bhuiyan, H. R.
10.1101/2020.07.30.226688 — microbiology — Posted on 2020-07-30
322 E-cigarettes compromise the gut barrier and trigger gut inflammation
Sharma, A.; Lee, J.; Fonseca, A.; Moshensky, A.; Kothari, T.; Ibrahim, I. S.; Ibeawuchi, S.-R.; Pranadinata, R.; Ear, J.; Sahoo, D.; Crotty-Alexander, L.; Ghosh, P.; Das, S.
10.1101/2020.07.29.227348 — immunology — Posted on 2020-07-30
323 Genomic prediction for malting quality traits in practical barley breeding programs
Sarup, P.; Edriss, V.; Kristensen, N. H.; Jensen, J. D.; Orabi, J.; Jahoor, A.; Jensen, J.
10.1101/2020.07.30.228007 — genetics — Posted on 2020-07-30
325 Laying Hens Affected By Newcastle Virus And Laryngotracheitis Virus Show Rapid Recovery After Treatment With Ivermectin
Fernandez-Diaz, M.; Guevara, L.; Icochea, E.; Montalvan, A.; Villanueva-Perez, D.; Fernandez-Sanchez, M.; Ticona, J.; Zimic, M.
10.1101/2020.07.29.226027 — microbiology — Posted on 2020-07-30
326 A Murine Model for the Transition of Streptococcus pneumoniae from Asymptomatic Colonizer to Systemic Pathogen
Joma, B. J.; Siwapornchai, N.; Vanguri, V. K.; Shrestha, A.; Roggensack, S. E.; Davidson, B. A.; Tai, A.; Hakansson, A. P.; Meydani, S. N.; Leong, J. M.; Bou Ghanem, E. N.
10.1101/2020.07.29.227991 — microbiology — Posted on 2020-07-30
331 Towards chemical accuracy for alchemical free energy calculations with hybrid physics-based machine learning / molecular mechanics potentials
Rufa, D. A.; Bruce Macdonald, H. E.; Fass, J.; Wieder, M.; Grinaway, P. B.; Roitberg, A. E.; Isayev, O.; Chodera, J. D.
10.1101/2020.07.29.227959 — biophysics — Posted on 2020-07-30
333 Exploring patterns of ongoing thought under naturalistic and task-based conditions
Konu, D.; Mckeown, B.; Turnbull, A.; Ho, N. S. P.; Vanderwal, T.; McCall, C.; Tipper, S. P.; Jefferies, E.; Smallwood, J.
10.1101/2020.07.29.226431 — neuroscience — Posted on 2020-07-30
338 3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system
Leung, C.; Robbins, S.; Moss, A.; Heal, M.; Osanlouy, M.; Christie, R.; Farahani, N.; Monteith, C.; Chen, J.; Hunter, P.; Tappan, S.; Vadigepalli, R.; Cheng, Z.; Schwaber, J. S.
10.1101/2020.07.29.227538 — neuroscience — Posted on 2020-07-30
339 Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
Choate, L. A.; Barshad, G.; McMahon, P. W.; Said, I.; Rice, E. J.; Munn, P. R.; Lewis, J. J.; Danko, C. G.
10.1101/2020.07.29.227660 — genetics — Posted on 2020-07-30
340 Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the N-nitrosourea-producing enzyme SznF
McBride, M. J.; Pope, S. R.; Hu, K.; Slater, J. W.; Okafor, C. D.; Balskus, E. P.; Bollinger, J. M.; Boal, A. K.
10.1101/2020.07.29.227702 — biochemistry — Posted on 2020-07-30
342 Physical activity and aerobic fitness show different associations with brain processes underlying anticipatory selective visuospatial attention in adolescents
Hernandez Barros, D.; Heinilä, E.; Muotka, J.; Ruotsalainen, I.; Lapinkero, H. M.; Syväoja, H.; Tammelin, T. H.; Parviainen, T.
10.1101/2020.07.29.227181 — neuroscience — Posted on 2020-07-30
347 Glycosylation of bioactive C13-apocarotenols in Nicotiana benthamiana and Mentha x piperita
Sun, G.; Putkaradze, N.; Bohnacker, S.; Joncyk, R.; Fida, T.; Hoffmann, T.; Bernhardt, R.; Härtl, K.; Schwab, W.
10.1101/2020.07.29.225110 — biochemistry — Posted on 2020-07-30
351 Plankton food webs of the Gulf of Mexico spawning grounds of Atlantic Bluefin tuna
Stukel, M. R.; Gerard, T.; Kelly, T. B.; Knapp, A. N.; Laiz-Carrion, R.; Lamkin, J.; Landry, M. R.; Malca, E.; Selph, K. E.; Shiroza, A.; Shropshire, T. A.; Swalethorp, R. R.
10.1101/2020.07.29.227116 — ecology — Posted on 2020-07-30
353 Bringing the pancreas patient back to the bench: Ex vivo culture of intact human patient derived pancreatic tumour tissue
Kokkinos, J.; Sharbeen, G.; Haghighi, K. S.; Ignacio, R. M. C.; Kopecky, C.; Gonzales-Aloy, E.; Youkhana, J.; Pandzic, E.; Boyer, C.; Davis, T. P.; Butler, L. M.; Goldstein, D.; McCarroll, J. A.; Phillips, P. A.
10.1101/2020.07.30.223925 — cancer biology — Posted on 2020-07-30
358 Parallel genetics of regulatory sequences in vivo
Froehlich, J.; Uyar, B.; Herzog, M.; Theil, K.; Glazar, P.; Akalin, A.; Rajewsky, N.
10.1101/2020.07.28.224998 — genetics — Posted on 2020-07-30
360 ExBoX: a simple Boolean exclusion strategy to drive expression in neurons
Vahedi-Hunter, T.; Ubina, T.; Gupta, A.; Wong, W.; Agnew-Svoboda, W.; Santhakumar, V.; Riccomagno, M. M.
10.1101/2020.07.28.224691 — neuroscience — Posted on 2020-07-30
362 Repression of Pdzrn3 is required for heart maturation and protects against heart failure
Pernot, M.; Paspard, b.; Abelanet, A.; rubin, s.; forfar, i.; cetran, l.; jeanningros, s.; han, m.; Balse, E.; hatem, s.; dufourcq, p.; couffinhal, t.; DUPLAA, c.
10.1101/2020.07.29.226597 — physiology — Posted on 2020-07-30
363 Vascular calcification has a role in acute non-renal phosphate clearance
Turner, M. E.; Lansing, A. P.; Jeronimo, P. S.; Lee, L. H.; Svajger, B. A.; Zelt, J. G.; Petkovich, M. P.; Holden, R. M.; Adams, M. A.
10.1101/2020.07.29.225532 — pathology — Posted on 2020-07-30
364 On the Digital Psychopharmacology of Valproic Acid in Mice
Bass, J. S.; Tuo, A.; Ton, L.; Jankovic, M.; Kapadia, P. P.; Schirmer, C.; Krishnan, V.
10.1101/2020.07.29.220350 — neuroscience — Posted on 2020-07-30
365 DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation
Morcom, L.; Edwards, T. J.; Rider, E.; Jones-Davis, D.; Lim, J. W.; Chen, K.-S.; Dean, R.; Bunt, J.; Ye, Y.; Gobius, I.; Suarez, R.; Mandelstam, S.; Sherr, E. H.; Richards, L. J.
10.1101/2020.07.29.227827 — neuroscience — Posted on 2020-07-30
366 Disentangling the sequence, cellular and ultrastructural determinants of Huntingtin nuclear and cytoplasmic inclusion formation
Riguet, N.; Mahul-Mellier, A.-L.; Maharjan, N.; Burtscher, J.; Patin, A.; Croisier, M.; Knott, G. W.; Reiterer, V.; Farhan, H.; Lashuel, H.
10.1101/2020.07.29.226977 — neuroscience — Posted on 2020-07-30
367 Visual field reconstruction using fMRI-based techniques
Carvalho, J.; Martins, J.; Invernizzi, A.; Jansonius, N. M.; Renken, R. J.; Cornelissen, F. W.
10.1101/2020.07.29.226258 — neuroscience — Posted on 2020-07-30
368 Genetically Determined Strength of Natural Killer Cells is Enhanced by Adaptive HLA class I Admixture in East Asians
Deng, Z.; Zhen, J.; Harrison, G. F.; Zhang, G.; Chen, R.; Sun, G.; Yu, Q.; Nemat-Gorgani, N.; Guethlein, L. A.; He, L.; Tang, M.; Gao, X.; Cai, S.; Shortt, J. A.; Gignoux, C. R.; Carrington, M.; Zou, H.; Parham, P.; Hong, W.; Norman, P. J.
10.1101/2020.07.29.227579 — immunology — Posted on 2020-07-30
369 Polygenic Risk Scores Predict the Development of Alcohol and Nicotine Use Problems from Adolescence through Young Adulthood
Deak, J. D.; Clark, D. A.; Liu, M.; Durbin, C. E.; Iacono, W. G.; McGue, M.; Vrieze, S. I.; Hicks, B. M.
10.1101/2020.07.29.227439 — genetics — Posted on 2020-07-30
371 Virtual Screening and Elucidation of Putative Binding Mode for Small Molecule Antagonist of BCL2 BH4 Domain
Joel, I. y.; Adigun, T. O.; AJIBOLA, A. O.; BANKOLE, O. O.; OZOJIOFOR, U. O.; REMI-ESAN, I. A.; SULAIMON, L. A.
10.1101/2020.07.29.226308 — bioinformatics — Posted on 2020-07-30
373 Activatable zymography probes enable in situ localization of protease dysregulation in cancer
Soleimany, A. P.; Kirkpatrick, J. D.; Su, S.; Dudani, J. S.; Zhong, Q.; Bekdemir, A.; Bhatia, S. N.
10.1101/2020.07.29.227413 — bioengineering — Posted on 2020-07-30
374 Intrinsically disordered protein ensembles shape evolutionary rates revealing conformational patterns
Palopoli, N.; Marchetti, J.; Monzon, A. M.; Zea, D. J.; Tosatto, S. C. E.; Fornasari, M. S.; Parisi, G.
10.1101/2020.07.29.227363 — bioinformatics — Posted on 2020-07-30
378 Validating gene-phenotype associations using relationships in the UMLS
Blumenfeld, A.; Gonzaga-Jauregui, C.; Sharma, D.; Geisinger-Regeneron DiscovEHR Collaboration, ; Yadav, A.; Khalid, S.; Balasubramanian, S.; Reid, J. G.; Habegger, L.; Cantor, M. N.; Staples, J.
10.1101/2020.07.29.226993 — bioinformatics — Posted on 2020-07-30
379 Automatic segmentation of dentate nuclei for microstructure assessment: example of application to temporal lobe epilepsy patients
Gaviraghi, M.; Giovanni Savini, G.; Castellazzi, G.; Palesi, F.; Rolandi, N.; Sacco, S.; Pichiecchio, A.; Mariani, V.; Tartara, E.; Tassi, L.; Vitali, P.; D'Angelo, E.; Gandini Wheeler-Kingshott, C. A. M.
10.1101/2020.07.29.222430 — bioengineering — Posted on 2020-07-30
380 Biofabrication using maize protein: 3D printing using zein formulations
Tavares-Negrete, J. A.; Aceves-Colin, A. E.; Rivera-Flores, D. C.; Diaz-Armas, G. G.; Mertgen, A.-S.; Trinidad-Calderon, P. A.; Olmos-Cordero, J. M.; Gomez-Lopez, E. G.; Perez-Carrillo, E.; Escobedo-Avellaneda, Z. J.; Tamayol, A.; Alvarez, M. M.; Trujillo-de Santiago, G.
10.1101/2020.07.29.227744 — bioengineering — Posted on 2020-07-30
382 Resistance to tembotrione, a 4-hydroxyphenylpyruvate dioxygenase-inhibitor, in Sorghum bicolor
Pandian, B. A.; Varanasi, A.; Vennapusa, A. R.; Rajendran, S.; Lin, G.; Zhao, M.; Tunnell, M.; Tesso, T.; Liu, S.; Prasad, P. V. V.; Jugulam, M.
10.1101/2020.07.29.227512 — plant biology — Posted on 2020-07-30
383 Heterodimeric insecticidal peptide provides new insights into the molecular and functional diversity of ant venoms
Touchard, A.; Mendel, H. C.; Boulogne, I.; Herzig, V.; Braga Emidio, N.; King, G. F.; Triquigneaux, M.; Jaquillard, L.; Beroud, R.; De Waard, M.; Delalande, O.; Dejean, A.; Muttenthaler, M.; Duplais, C.
10.1101/2020.07.29.226878 — pharmacology and toxicology — Posted on 2020-07-30
387 Circadian timing-dependent myoblast differentiation and muscle regeneration
Katoku-Kikyo, N.; Paatela, E.; Houtz, D. L.; Lee, B.; Munson, D.; Wang, X.; Hussein, M.; Bhatia, J.; Lim, S.; Yuan, C.; Asakura, Y.; Asakura, A.; Kikyo, N.
10.1101/2020.07.29.209312 — developmental biology — Posted on 2020-07-30
389 Read counts from environmental DNA (eDNA) metabarcoding reflect fish abundance and biomass in drained ponds
Di Muri, C.; Lawson Handley, L. J.; Bean, C. W.; Li, J.; Peirson, G.; Sellers, G. S.; Walsh, K.; Watson, H. V.; Winfield, I. J.; Hänfling, B.
10.1101/2020.07.29.226845 — molecular biology — Posted on 2020-07-30
395 Control and mechanisms of pulsatile flows in epithelial monolayers
Thiagarajan, R.; Bhat, A.; Salbreux, G.; Inamdar, M. M.; Riveline, D.
10.1101/2020.07.29.226357 — biophysics — Posted on 2020-07-30
398 Non-parametric modelling of temporal and spatial counts data from RNA-seq experiments
BinTayyash, N.; Georgaka, S.; John, S.; Ahmed, S.; Boukouvalas, A.; Hensman, J.; Rattray, M.
10.1101/2020.07.29.227207 — bioinformatics — Posted on 2020-07-30
400 Dissection of the corticotroph transcriptome in a mouse model of glucocorticoid-induced suppression of the HPA axis
Romano, N.; Duncan, P.; McClafferty, H.; Nolan, O.; Ding, Q.; Homer, N. Z.; Le Tissier, P.; Walker, B. R.; Shipston, M. J.; Chambers, T. J. G.
10.1101/2020.07.29.227330 — physiology — Posted on 2020-07-30
401 Metabolic effects of aripiprazole and olanzapine multiple-dose treatment in healthy volunteers. Association with pharmacogenetics.
Koller, D.; Almenara, S.; Mejia, G.; Saiz-Rodriguez, M.; Zubiaur, P.; Roman, M.; Ochoa, D.; Navares-Gomez, M.; Santos-Molina, E.; Pintos-Sanchez, E.; Abad-Santos, F.
10.1101/2020.07.29.226209 — pharmacology and toxicology — Posted on 2020-07-30
403 The molecular taxonomy of primate amygdala via single-nucleus RNA-sequencing analysis
Zhang, L.; Cheng, Y.; Wu, S.; Lu, Y.; Xue, Z.; Chen, D.; Zhang, B.; Qiu, Z.; Jiang, H.
10.1101/2020.07.29.226829 — neuroscience — Posted on 2020-07-30
404 A spatially-tracked single cell transcriptomics map of neuronal networks in the intrinsic cardiac nervous system
Moss, A.; Robbins, S.; Achanta, S.; Kuttippurathu, L.; Turick, S.; Nieves, S.; Hanna, P.; Smith, E. H.; Hoover, D. B.; Chen, J.; Cheng, Z.; Ardell, J. L.; Shivkumar, K.; Schwaber, J. S.; Vadigepalli, R.
10.1101/2020.07.29.227090 — neuroscience — Posted on 2020-07-30
406 Gut Phageome Analysis Reveals Disease-Specific Hallmarks in Childhood Obesity
Bikel, S.; Gamaliel Lopez-Leal, G.; Cornejo-Granados, F.; Gallardo-Becerra, L.; Sanchez, F.; Equihua-Medina, E.; Ochoa-Romo, J. P.; Lopez-Contreras, B. E.; Canizales-Quinteros, S.; Ochoa-Leyva, A.
10.1101/2020.07.29.227637 — genomics — Posted on 2020-07-30
408 Genomic insights into the host specific adaptation of the Pneumocystis genus and emergence of the human pathogen Pneumocystis jirovecii
Cisse, O. H.; Ma, L.; Dekker, J. P.; Khil, P. P.; Youn, J.-H.; Brenchley, J. M.; Blair, R. V.; Pahar, B.; Chabe, M.; Van Rompay, K. K. A.; Keesler, R.; Sukura, A.; Hirsch, V.; Kutty, G.; Liu, Y.; Li, P.; Chen, J.; Song, J.; Weissenbacher-Lang, C.; Xu, J.; Upham, N. S.; Stajich, J. E.; Cuomo, C. A.; Cushion, M. T.; Kovacs, J. A.
10.1101/2020.07.29.227421 — evolutionary biology — Posted on 2020-07-30
410 Single-nuclei transcriptomics of schizophrenia prefrontal cortex primarily implicates neuronal subtypes
Reiner, B. C.; Crist, R. C.; Stein, L. M.; Weller, A. E.; Doyle, G. A.; Arauco-Shapiro, G.; Ferraro, T. N.; Hayes, M. R.; Berrettini, W. H.
10.1101/2020.07.29.227355 — neuroscience — Posted on 2020-07-29
411 Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior
Kölsch, Y.; Hahn, J.; Sappington, A.; Stemmer, M.; Fernandes, A. M.; Helmbrecht, T. O.; Lele, S.; Butrus, S.; Laurell, E.; Arnold-Ammer, I.; Shekhar, K.; Sanes, J.; Baier, H.
10.1101/2020.07.29.226050 — neuroscience — Posted on 2020-07-29
413 MafF is an anti-viral host factor that suppresses transcription from Hepatitis B Virus and Epstein Barr Virus promoters
Ibrahim, M. K.; ALY, S.; Wakae, K.; Sugiyama, M.; Tsuge, M.; Ito, M.; Watashi, K.; Zheng, X.; Murata, T.; El Kassas, M.; Kato, T.; Murayama, A.; Suzuki, T.; Chayama, K.; Shimotohno, K.; Muramatsu, M.; Aly, H. H.; Wakita, T.
10.1101/2020.07.29.227793 — microbiology — Posted on 2020-07-29
419 Disease-Linked Super-Trafficking of a Mutant Potassium Channel
Huang, H.; Chamness, L. M.; Vanoye, C. G.; Kuenze, G.; Meiler, J.; George, A. L.; Schlebach, J. P.; Sanders, C.
10.1101/2020.07.29.227231 — biophysics — Posted on 2020-07-29
420 Motifs of the C-terminal Domain of MCM9 Direct Localization to Sites of Mitomycin-C Damage for RAD51 Recruitment
McKinzey, D. R.; Gomanthinayagam, S.; Griffin, W. C.; Klinzing, K. N.; Jeffries, E. P.; Rajkovic, A.; TRAKSELIS, M.
10.1101/2020.07.29.227678 — biochemistry — Posted on 2020-07-29
422 Pre- and post-target cortical processes predict speech-in-noise performance
Kim, S.; Schwalje, A. T.; Liu, A. S.; Gander, P. E.; McMurray, B.; Griffiths, T. D.; Choi, I.
10.1101/817460 — neuroscience — Posted on 2020-07-29
424 Adaptable and Efficient Genome Editing by sgRNA-Cas9 Protein Co-injection into Drosophila
Nyberg, K. G.; Nguyen, J. Q.; Kwon, Y.-J.; Blythe, S. A.; Beitel, G. J.; Carthew, R. W.
10.1101/2020.05.07.080762 — genetics — Posted on 2020-07-29
429 The ciliary protein IFT88 controls post-natal cartilage thickness and influences development of osteoarthritis.
Coveney, C. R.; Zhu, L.; Miotla-Zarebska, J.; Stott, B.; Parisi, I.; Batchelor, V.; Duarte, C.; Chang, E.; McSorley, E.; Vincent, T. L.; Wann, A. K.
10.1101/2020.07.29.225599 — molecular biology — Posted on 2020-07-29
430 Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes
Mangiameli, E.; Cecchele, A.; Morena, F.; Sanvito, F.; Matafora, V.; Cattaneo, A.; Della Volpe, L.; Gnani, D.; Paulis, M.; Susani, L.; Martino, S.; Di Micco, R.; Bachi, A.; Gritti, A.
10.1101/2020.03.13.990176 — genetics — Posted on 2020-07-29
431 Loss of Kinesin-8 improves the robustness of the acentrosomal spindle
Pineda-Santaella, A.; Fernandez-Castillo, N.; Sanchez-Gomez, A.; Fernandez-Alvarez, A.
10.1101/2020.07.29.226506 — cell biology — Posted on 2020-07-29
435 Tet1 isoforms differentially regulate gene expression, synaptic transmission and memory in the mammalian brain.
Greer, C. B.; Wright, J.; Weiss, J. D.; Lazarenko, R. M.; Moran, S. P.; Zhu, J.; Chronister, K. S.; Jin, A. Y.; Kennedy, A. J.; Sweatt, J. D.; Kaas, G. A.
10.1101/2020.07.27.223685 — neuroscience — Posted on 2020-07-29
436 Dynamics of the Cortico-Cerebellar Loop Fine-Tune Dexterous Movement
Guo, J.-Z.; Sauerbrei, B.; Cohen, J.; Mischiati, M.; Graves, A.; Pisanello, F.; Branson, K.; Hantman, A.
10.1101/637447 — neuroscience — Posted on 2020-07-29
445 An atlas of lamina-associated chromatin across thirteen human cell types reveals cell-type-specific and multiple subtypes of peripheral heterochromatin
Keough, K. C.; Shah, P. P.; Wickramasinghe, N. M.; Dundes, C. E.; Chen, A.; Salomon, R. E. A.; Whalen, S.; Loh, K. M.; Dubois, N.; Pollard, K. S.; Jain, R.
10.1101/2020.07.23.218768 — developmental biology — Posted on 2020-07-29
449 Phytohormone production by the arbuscular mycorrhizal fungus Rhizophagus irregularis
Pons, S.; Fournier, S.; Chervin, C.; Becard, G.; Rochange, S.; Frei-dit-frey, N.; Puech-pages, V.
10.1101/2020.06.11.146126 — plant biology — Posted on 2020-07-29
451 Neural representation of linguistic feature hierarchy reflects second-language proficiency
Di Liberto, G.; Nie, J.; Yeaton, J.; Khalighinejad, B.; Shamma, S.; Mesgarani, N.
10.1101/2020.06.15.142554 — neuroscience — Posted on 2020-07-29
454 Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination.
Voic, H.; de Vries, R. D.; Sidney, J.; Rubiro, P.; Moore, E.; Phillips, E. J.; Mallal, S.; Schwan, B.; Weiskopf, D.; Grifoni, A.; Sette, A.
10.1101/2020.07.29.227082 — immunology — Posted on 2020-07-29
455 Independent somatic evolution underlies multifocal small intestine neuroendocrine tumors
Elias, E.; Ardalan, A.; Lindberg, M.; Reinsbach, S.; Muth, A.; Nilsson, O.; Arvidsson, Y.; Larsson, E.
10.1101/2020.05.06.080499 — genomics — Posted on 2020-07-29
456 Artificial light at night amplifies seasonal relapse of haemosporidian parasites in a widespread songbird
Becker, D. J.; Singh, D.; Pan, Q.; Montoure, J. D.; Talbott, K. M.; Wanamaker, S.; Ketterson, E. D.
10.1101/2020.06.22.163998 — ecology — Posted on 2020-07-29
458 A polycomb-independent role of EZH2 in TGFβ1-damaged epithelium triggers a fibrotic cascade with mesenchymal cells
Le, H. Q.; Hill, M. A.; Kollak, I.; Skronska-Wasek, W.; Schroeder, V.; Wirth, J.; Schruf, E.; Quast, K.; Herrmann, F. E.; Thomas, M. J.; Garnett, J. P.
10.1101/2020.07.29.225300 — cell biology — Posted on 2020-07-29
462 Halophytic bacterial endophytome: a potential source of beneficial microbes for a sustainable agriculture
Christakis, C. A.; Daskalogiannis, G.; Chatzakis, A.; Markakis, E. A.; Sagia, A.; Rizzo, G. F.; Catara, V.; Lagkouvardos, I.; Studholme, D. J.; Sarris, P. F.
10.1101/2020.07.29.226860 — microbiology — Posted on 2020-07-29
467 Structures of the germline-specific Deadhead and Thioredoxin T proteins from Drosophila melanogaster reveal unique features among Thioredoxins
Freier, R.; Aragon, E.; Baginski, B.; Pluta, R.; Martin-Malpartida, P.; Ruiz, L.; Condeminas, M.; Gonzalez, C.; Macias, M. J.
10.1101/2020.07.29.226944 — molecular biology — Posted on 2020-07-29
468 Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation
Esposito, C. L.; Autiero, I.; Basal, M. A.; Sandomenico, A.; Ummarino, S.; Borchiellini, M.; Ruvo, M.; Catuogno, S.; Ebralidze, A. K.; de Franciscis, V.; Di Ruscio, A.
10.1101/2020.07.29.226803 — molecular biology — Posted on 2020-07-29
469 APOBEC2 binds Chromatin and Represses Transcription during Myoblast Differentiation
Lorenzo, J. P.; Molla, L.; Ibarra, I. L.; Ruf, S.; Subramani, P. G.; Boulais, J.; Harjanto, D.; Vonica, A.; Di Noia, J. M.; Dieterich, C.; Zaugg, J. B.; Papavasiliou, F. N.
10.1101/2020.07.29.223594 — molecular biology — Posted on 2020-07-29
471 Faster Cryptococcus melanization increases virulence in experimental and human cryptococcosis
Sousa, H. R. d.; Oliveira, G. P. d.; Frazao, S. d. O.; Gorgonha, K. C. d. M.; Rosa, C. P.; Garcez, E. M.; Lucas, J.; Correia, A. F.; Freitas, W. F. d.; Paes, H. C.; Trilles, L.; Lazera, M. d. S.; Pinto, V. L.; Felipe, M. S. S.; Casadevall, A.; Silva-Pereira, I.; Albuquerque, P.; Nicola, A. M.
10.1101/2020.07.29.222794 — microbiology — Posted on 2020-07-29
472 Paracoccidioides HSP90 can be found in the cell surface and is a target for antibodies with therapeutic potential
Moura, A. N. D.; Oliveira, D. S. L. d.; Paredes, V.; Rocha, L. B.; Casadevall, A.; Albuquerque, P.; Felipe, M. S. S.; Piazza, R. M. F.; Nicola, A. M.
10.1101/2020.07.29.198804 — microbiology — Posted on 2020-07-29
474 Enhanced BCR signalling inflicts early plasmablast and germinal centre B cell death
Yam-Puc, J. C.; Zhang, L.; Maqueda-Alfaro, R. A.; Garcia-Ibanez, L.; Zhang, Y.; Davies, J.; Senis, Y. A.; Snaith, M.; Toellner, K.-M.
10.1101/2020.07.29.226662 — immunology — Posted on 2020-07-29
475 The genetic variants analysis of circulating SARS-CoV-2 in Bangladesh.
Mahmud, A. S. M.; Taznin, T.; Sarkar, M. M. H.; Uzzaman, M. S.; Osman, E.; Habib, M. A.; Akter, S.; Banu, T. A.; Goswami, B.; Jahan, I.; Hossain, M. S.; Khan, M. S.
10.1101/2020.07.29.226555 — genomics — Posted on 2020-07-29
478 XLF acts as a flexible connector during non-homologous end joining
Carney, S. M.; Moreno, A. T.; Piatt, S. C.; Cisneros-Aguirre, M.; Lopezcolorado, F. W.; Stark, J. M.; Loparo, J. J.
10.1101/2020.07.29.227033 — biochemistry — Posted on 2020-07-29
481 Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis
Ferrarini, M. G.; Lal, A.; Rebollo, R.; Gruber, A.; Guarracino, A.; Martinez Gonzalez, I.; Floyd, T.; Siqueira de Oliveira, D.; Shanklin, J.; Beausoleil, E.; Pusa, T.; Pickett, B.; Aguiar-Pulido, V.
10.1101/2020.07.28.225581 — bioinformatics — Posted on 2020-07-29
482 Infection of human lymphomononuclear cells by SARS-CoV-2
Pontelli, M. C.; Castro, I. A.; Martins, R. B.; Veras, F. P.; LaSerra, L.; Nascimento, D. C.; Cardoso, R. S.; Rosales, R.; Caetite, D. B.; Lima, M. H.; Lima, T. M.; Souza, J. P.; Kawahisa, J. T.; Giannini, M. C.; Bonjorno, L. P.; Lopes, M. I.; Batah, S. S.; Siyuan, L.; Assad, R. L.; Almeida, S. C.; Oliveira, F. R.; Benatti, M. N.; Pontes, L. L.; Santana, R. C.; Villar, F. C.; Martins, M. A.; Cunha, T. M.; Calado, R. T.; Alves-Filho, J. C.; Zamboni, D. S.; Fabro, A.; Louzada-Junior, P.; Louzada-Junior, P.; Oliveira, R. D.; Cunha, F. Q.; Arruda, E.
10.1101/2020.07.28.225912 — microbiology — Posted on 2020-07-29
483 Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stemcell-derived airway repair response
Purkayastha, A.; Sen, C.; Garcia, G.; Langerman, J.; Vijayaraj, P.; Shia, D. W.; Meneses, L. K.; Rickabaugh, T. M.; Mulay, A.; Konda, B.; Sim, M. S.; Stripp, B. R.; Plath, K.; Arumugaswami, V.; Gomperts, B. N.
10.1101/2020.07.28.226092 — cell biology — Posted on 2020-07-29
484 Structural and functional analysis of female sex hormones against SARS-Cov2 cell entry
Aguilar Pineda, J.; Albaghdadi, M.; Jiang, W.; Vera Lopez, K. J.; Lindsay, M. E.; Davila del-Carpio, G.; Gomez Valdez, B.; Malhotra, R.; Lino Cardenas, C. L.
10.1101/2020.07.29.227249 — cell biology — Posted on 2020-07-29
485 Allosteric inhibition of the SARS-CoV-2 main protease - insights from mass spectrometry-based assays
El-Baba, T. J.; Lutomski, C. A.; Kantsadi, A. L.; Malla, T. R.; John, T.; Mikhailov, V.; Bolla, J. R.; Schofield, C. J.; Zitzmann, N.; Vakonakis, I.; Robinson, C. V.
10.1101/2020.07.29.226761 — biophysics — Posted on 2020-07-29
486 Intradermal-delivered DNA vaccine provides anamnestic protection in a rhesus macaque SARS-CoV-2 challenge model
Patel, A.; Walters, J.; Reuschel, E. L.; Schultheis, K.; Parzych, E.; Gary, E. N.; Maricic, I.; Purwar, M.; Eblimit, Z.; Walker, S. N.; Guimet, D.; Bhojnagarwala, P.; Doan, A.; Xu, Z.; Elwood, D.; Reeder, S. M.; Pessaint, L.; Kim, K. Y.; Cook, A.; Chokkalingam, N.; Finneyfrock, B.; Tello-Ruiz, E.; Dodson, A.; Choi, J.; Generotti, A.; Harrison, J.; Tursi, N. J.; Andrade, V. M.; Dia, Y.; Zaidi, F. I.; Anderson, H.; Lewis, M. G.; Muthumani, K.; Kim, J. J.; Kulp, D. W.; Humeau, L. M.; Ramos, S.; Smith, T. R.; Weiner, D. B.; Broderick, K. E.
10.1101/2020.07.28.225649 — immunology — Posted on 2020-07-29
487 Classification of complex emotions using EEG and virtual environment: proof of concept and therapeutic implication
De Filippi, E.; Wolter, M.; Melo, B.; Tierra Criollo, C. J.; Soares Bortolini, T.; Deco, G.; Moll, J.
10.1101/2020.07.27.223370 — neuroscience — Posted on 2020-07-29
492 Diversification slowdown in an evolutionary cul-de-sac
Perez-Lamarque, B.; Opik, M.; Maliet, O.; Afonso Silva, A. C.; Selosse, M.-A.; Martos, F.; Morlon, H.
10.1101/2020.07.28.224790 — evolutionary biology — Posted on 2020-07-29
494 Selecting Student-Authored Questions for Summative Assessments
Huang, A.; Hancock, D.; Clemson, M.; Yeo, G.; Harney, D. J.; Denny, P.; Denyer, G.
10.1101/2020.07.28.225953 — scientific communication and education — Posted on 2020-07-29
497 Deep Texture Representations as a Universal Encoder for Pan-cancer Histology
Komura, D.; Kawabe, A.; Fukuta, K.; Sano, K.; Umezaki, T.; Koda, H.; Suzuki, R.; Tominaga, K.; Konishi, H.; Nishida, S.; Furuya, G.; Katoh, H.; Ushiku, T.; Fukayama, M.; Ishikawa, S.
10.1101/2020.07.28.224253 — cancer biology — Posted on 2020-07-29
501 Optimized gene expression from bacterial chromosome by high-throughput integration and screening
Saleski, T. E.; Chung, M. T.; Carruthers, D. N.; Khasbaatar, A.; Kurabayashi, K.; Lin, X.
10.1101/2020.07.29.226290 — synthetic biology — Posted on 2020-07-29
502 Discovery of a Novel, Selective and Short-Acting Skeletal Myosin II Inhibitor
Radnai, L.; Surman, M.; Hafenbreidel, M.; Young, E. J.; Stremel, R. F.; Lin, L.; Pasetto, P.; Jin, X.; Geedy, M.; Partridge, J.-R.; Patel, A.; Conlon, M.; Sellers, J. R.; Cameron, M. D.; Rumbaugh, G.; Griffin, P.; Kamenecka, T. M.; Miller, C. A.
10.1101/2020.07.28.225383 — pharmacology and toxicology — Posted on 2020-07-29
503 Drug Screening with Zebrafish Visual Behavior Identifies Carvedilol as a Potential Treatment for Retinitis Pigmentosa
Ganzen, L.; Ko, M. J.; Zhang, M.; Xie, R.; Chen, Y.; Zhang, L.; James, R.; Mumm, J.; van Rijn, R.; Zhong, W.; Pang, C. P.; Zhang, M.; Tsujikawa, M.; Leung, Y. F.
10.1101/2020.07.28.225789 — neuroscience — Posted on 2020-07-29
507 Parallel genetics of regulatory sequences in vivo
Froehlich, J.; Uyar, B.; Herzog, M.; Theil, K.; Glazar, P.; Akalin, A.; Rajewsky, N.
10.1101/2020.07.28.224998 — genetics — Posted on 2020-07-29
509 High-resolution positron emission microscopy of patient-derived tumor organoids
Khan, S.; Shin, J. H.; Ferri, V.; Cheng, N.; Noel, J. E.; Kuo, C.; Sunwoo, J. B.; Pratx, G.
10.1101/2020.07.28.220343 — cancer biology — Posted on 2020-07-29
513 Patient-tailored design of AML cell subpopulation-selective drug combinations
Ianevski, A.; Lahtela, J.; Javarappa, K. K.; Sergeev, P.; Ghimire, B.; Gautam, P.; Vaha-Koskela, M.; Turunen, L.; Linnavirta, N.; Kuusanmaki, H.; Kontro, M.; Porkka, K.; Heckman, C.; Mattila, P.; Wennerberg, K.; Giri, A. K.; Aittokallio, T.
10.1101/2020.07.28.222034 — systems biology — Posted on 2020-07-29
514 MAGIC: A label-free fluorescence method for 3D high-resolution reconstruction of myelinated fibers in large volumes
Costantini, I.; Baria, E.; Sorelli, M.; Matuschke, F.; Giardini, F.; Menzel, M.; Mazzamuto, G.; Silvestri, L.; Cicchi, R.; Amunts, K.; Axer, M.; Pavone, F. S.
10.1101/2020.07.28.225011 — neuroscience — Posted on 2020-07-29
515 High resolution mouse subventricular zone stem cell niche transcriptomereveals features of lineage, anatomy, and aging
Xie, X. P.; Laks, D. R.; Sun, D.; Poran, A.; Laughney, A. M.; Wang, Z.; Sam, J.; Belenguer, G.; Farinas, I.; Elemento, O.; Zhou, X.; Parada, L. F.
10.1101/2020.07.27.223602 — neuroscience — Posted on 2020-07-29
523 ExBoX: a simple Boolean exclusion strategy to drive expression in neurons
Vahedi-Hunter, T.; Ubina, T.; Gupta, A.; Wong, W.; Agnew-Svoboda, W.; Santhakumar, V.; Riccomagno, M. M.
10.1101/2020.07.28.224691 — neuroscience — Posted on 2020-07-29
525 Bayesian model selection favors parametric over categorical models of the fMRI subsequent memory effect in young and elderly adults
Soch, J.; Richter, A.; Schuetze, H.; Kizilirmak, J. M.; Assmann, A.; Knopf, L.; Raschick, M.; Schult, A.; Maass, A.; Ziegler, G.; Richardson-Klavehn, A.; Duezel, E.; Schott, B. H.
10.1101/2020.07.27.220871 — neuroscience — Posted on 2020-07-29
526 Characterization of the gut DNA and RNA viromes in a cohort of Chinese residents and visiting Pakistanis
Yan, Q.; Wang, Y.; Chen, X.; Jin, H.; Wang, G.; Guan, K.; Zhang, Y.; Zhang, P.; Ayaz, T.; Liang, Y.; Wang, J.; Cui, G.; Sun, Y.; Xiao, M.; Zhang, A.; Li, P.; Liu, X.; Ma, Y.; Li, S.; Ma, T.
10.1101/2020.07.28.226019 — microbiology — Posted on 2020-07-29
531 SMAD2 promotes myogenin expression and terminal myogenic differentiation.
Lamarche, E.; AlSudais, H.; Rajgara, R.; Fu, D.; Omaiche, S.; Wiper-Bergeron, N.
10.1101/2020.07.28.225888 — cell biology — Posted on 2020-07-29
532 Metabolism of glucose and glutamine is critical for skeletal muscle stem cell activation.
Rodgers, J. T.; Ahsan, S.; Raval, M. H.; Ederer, M.; Tiwari, R. L.; Chareunsouk, A.
10.1101/2020.07.28.225847 — cell biology — Posted on 2020-07-29
533 Wavefront-sensorless adaptive optics with a laser-free spinning disk confocal microscope
Hussain, S. A.; Kubo, T.; Hall, N. J.; Gala, D.; Hampson, K.; Parton, R. M.; Phillips, M. A.; Wincott, M.; Fujita, K.; Davis, I.; Dobbie, I. M.; Booth, M. J.
10.1101/2020.07.28.225607 — cell biology — Posted on 2020-07-29
538 Synaptotagmins Maintain Diacylglycerol Homeostasis at Endoplasmic Reticulum-Plasma Membrane Contact Sites during Abiotic Stress
Ruiz-Lopez, N.; Perez-Sancho, J.; Esteban del Valle, A.; Haslam, R. P.; Vanneste, S.; Catala, R.; Perea-Resa, C.; Van Damme, D.; Garcia-Hernandez, S.; Albert, A.; Vallarino, J.; Lin, J.; Friml, J.; Macho, A.; Salinas, J.; Rosado, A.; Napier, J. A.; Amorim-Silva, V.; Botella, M. A.
10.1101/2020.07.28.222919 — molecular biology — Posted on 2020-07-29
539 Simplexviruses successfully adapt to their host by fine-tuning immune responses
Mozzi, A.; Cagliani, R.; Pontremoli, C.; Forni, D.; Saulle, I.; Saresella, M.; Pozzoli, U.; Clerici, M.; Biasin, M.; Sironi, M.
10.1101/2020.07.28.226126 — microbiology — Posted on 2020-07-29
540 Mutagenicity of folic acid deficiency and supplementation is tissue-specific and results in distinct mutation profiles
Diaz G., S.; Leblanc, D. P.; Gagne, R.; Behan, N. A.; Wong, A.; Marchetti, F.; MacFarlane, A. J.
10.1101/2020.07.27.223552 — genetics — Posted on 2020-07-29
542 Effects of osteogenic ambulatory mechanical stimulation on early stages of BMP-2mediated bone repair
Klosterhoff, B. S.; Vantucci, C. E.; Kaiser, J.; Ong, K. G.; Wood, L. B.; Weiss, J. A.; Guldberg, R. E.; Willett, N. J.
10.1101/2020.07.28.225870 — bioengineering — Posted on 2020-07-29
544 Biomarkers of Memory Variability in Traumatic Brain Injury
Adamovich-Zeitlin, R.; Wanda, P. A.; Solomon, E. A.; Phan, T.; Lega, B.; Jobst, B. C.; Gross, R. E.; Ding, K.; Diaz-Arrastia, R.; Kahana, M. J.
10.1101/2020.07.27.223073 — neuroscience — Posted on 2020-07-29
547 NEURAL ENCODING OF FELT AND IMAGINED TOUCH WITHIN HUMAN POSTERIOR PARIETAL CORTEX
Chivukula, S.; Zhang, C.; Aflalo, T.; Jafari, M.; Pejsa, K.; Pouratian, N.; Andersen, R. A.
10.1101/2020.07.27.223636 — neuroscience — Posted on 2020-07-29
549 Larger organ size caused by obesity is a mechanism for higher cancer risk.
Grant, H.; Zhang, Y.; Li, L.; Wang, Y.; Kawamoto, S.; Penisson, S.; Fouladi, D. F.; Shayesteh, S.; Blanco, A.; Ghandili, S.; Zinreich, E.; Graves, J. S.; Park, S.; Kern, S.; Hooper, J.; Yuille, A. L.; Fishman, E. K.; Chu, L.; Tomasetti, C.
10.1101/2020.07.27.223529 — cancer biology — Posted on 2020-07-29
550 Mind reading of the proteins: Deep-learning to forecast molecular dynamics
Gupta, C.; Cava, J. K.; Sarkar, D.; Wilson, E. A.; Vant, J.; Murray, S.; Singharoy, A.; Karmaker, S. K.
10.1101/2020.07.28.225490 — biophysics — Posted on 2020-07-29
551 Impact of endotoxins in gelatine hydrogels on chondrogenic differentiation and inflammatory cytokine secretion in vitro
Groen, W.; Utomo, L.; Castilho, M.; Gawlitta, D.; Malda, J.; van Weeren, R.; Levato, R.; Korthagen, N.
10.1101/2020.07.28.224451 — bioengineering — Posted on 2020-07-29
552 From plants to ants: Fungal modification of leaf lipids for nutrition and communication in the leaf-cutter ant fungal garden ecosystem
Khadempour, L.; Kyle, J. E.; Webb-Robertson, B.-J. M.; Nicora, C. D.; Smith, F. B.; Smith, R. D.; Lipton, M. S.; Currie, C. R.; Baker, E. S.; Burnum-Johnson, K. E.
10.1101/2020.07.28.224139 — systems biology — Posted on 2020-07-29
553 TOR coordinates with transcriptional and chromatin machinery to regulate thermotolerance and thermomemory
Sharma, M.; K, M. J.; Shukla, B. N.; Sharma, M.; Awasthi, P.; Mahtha, S. K.; Yadav, G.; Laxmi, A.
10.1101/2020.07.28.224634 — plant biology — Posted on 2020-07-29
555 Natural food intake patterns do not synchronize peripheral clocks
Xie, X.; Kukino, A.; Calcagno, H. E.; Berman, A.; Garner, J. P.; Butler, M. P.
10.1101/2020.07.28.220509 — physiology — Posted on 2020-07-29
560 Substrate-induced clustering activates Trim-Away of pathogens and proteins
Zeng, J.; Santos, A. F.; Mukadam, A.; Osswald, M.; Luptak, J.; Jacques, D.; Dickson, C.; Renner, N.; Johnson, C.; Vaysburd, M.; McEwan, W. A.; Morais-de-Sa, E.; Clift, D.; James, L. C.
10.1101/2020.07.28.225359 — molecular biology — Posted on 2020-07-29
561 Heparin as an Anti-Inflammatory Agent
Litov, L.; Petkov, P.; Rangelov, M.; Ilieva, N.; Lilkova, E.; Todorova, N.; Krachmarova, E.; Malinova, K.; Gospodinov, A.; Hristova, R.; Ivanov, I.; Nacheva, G.
10.1101/2020.07.29.223859 — molecular biology — Posted on 2020-07-29
564 Evaluation of Polygenic Prediction Methodology within a Reference-Standardized Framework
Pain, O.; Glanville, K. P.; Hagenaars, S. P.; Selzam, S. P.; Fürtjes, A. E.; Gaspar, H. A.; Coleman, J. R.; Rimfeld, K.; Breen, G.; Plomin, R.; Folkersen, L.; Lewis, C. M.
10.1101/2020.07.28.224782 — genomics — Posted on 2020-07-29
568 Relationship Between Neuroendocrine and Immune Gene Expression in Small Cell Lung Cancer
Cai, L.; Liu, H.; Huang, F.; Fujimoto, J.; Girard, L.; Chen, J.; Li, Y.; Zhang, Y.-a.; Deb, D.; Stastny, V.; Kuo, C. S.; Jia, G.; Yang, C.; Zou, W.; Aloma, A.; Huffman, K.; Papari-Zareei, M.; Yang, L.; Drapkin, B.; Akbay, E.; Shames, D. S.; Wistuba, I. I.; Wang, T.; Xiao, G.; DeBerardinis, R. J.; Minna, J. D.; Xie, Y.; Gazdar, A. F.
10.1101/2020.07.28.225763 — cancer biology — Posted on 2020-07-29
571 UNCG RNA tetraloop as a formidable force-field challenge for MD simulations
Mrazikova, K.; Mlynsky, V.; Kuhrova, P.; Pokorna, P.; Kruse, H.; Krepl, M.; Otyepka, M.; Banas, P.; Sponer, J.
10.1101/2020.07.27.223826 — biophysics — Posted on 2020-07-29
574 Epitope Prediction of Antigen Protein using Attention-Based LSTM Network
Nomi, T.; Inoue, S.; Fujita, H.; Sadamitsu, K.; Sakaguchi, M.; Tenma, A.; Nakagami, H.
10.1101/2020.07.27.224121 — bioinformatics — Posted on 2020-07-29
577 The PopN gate-keeper complex acts on the ATPase PscN to regulate the T3SS secretion switch from early to middle substrates in Pseudomonas aeruginosa
Ngo, T. D.; Perdu, C.; Jneid, B.; Ragno, M.; Novion Ducassou, J.; Kraut, A.; Coute, Y.; Stopford, C.; Attree, I.; Rietsch, A.; Faudry, E.
10.1101/2020.07.28.224923 — biochemistry — Posted on 2020-07-29
580 Lipidome profiles of plasma microvesicles differ in experimental cerebral malaria, compared to malaria without neurological complications
Batarseh, A. M.; Vafaee, F.; Hosseini-Beheshti, E.; Chen, A.; Cohen, A.; Juillard, A.; Hunt, N. H.; Mariani, M.; Mitchell, T.; Grau, G. E. R.
10.1101/2020.07.28.224170 — pathology — Posted on 2020-07-29
583 MSK phosphorylation of H3S28 is required for immediate early gene induction and cardiac hypertrophy
Robinson, E. L.; Drawnel, F. M.; Mehdi, S.; Archer, C. R.; Liu, W.; Okkenhaug, H.; Alkass, K.; Aronsen, J. M.; Nagaraju, C. K.; Sjaastad, I.; Sipido, K. R.; Bergmann, O.; Arthur, J. S. C.; Wang, X.; Roderick, H. L.
10.1101/2020.07.28.224832 — molecular biology — Posted on 2020-07-29
586 Digital spatial profiling of coronary plaques from persons living with HIV reveals high levels of STING and CD163 in macrophage enriched regions
Wanjalla, C. N.; Guo, L.; Fuller, D. T.; Mashayekhi, M.; Bailin, S.; Gabriel, C. L.; Temu, T.; Gong, J.; Liang, Y.; Virmani, R.; Finn, A. V.; Kalams, S. A.; Mallal, S. A.; Miner, J.; Beckman, J. A.; Koethe, J. R.
10.1101/2020.07.28.221325 — immunology — Posted on 2020-07-29
587 Biallelic mutation of CLRN2 causes non-syndromic hearing loss in humans
Vona, B.; Mazaheri, N.; Lin, S.-J.; Dunbar, L. A.; Maroofian, R.; Azaiez, H.; Booth, K. T.; Vitry, S.; Rad, A.; Varshney, P.; Fowler, B.; Alagramam, K. N.; Murphy, D.; Shariati, G.; Sedaghat, A.; Houlden, H.; VijayKumar, S.; Smith, R. J. H.; Haaf, T.; El-Amraoui, A.; Bowl, M. R.; Varshney, G. K.; Galehdari, H.
10.1101/2020.07.29.222828 — genetics — Posted on 2020-07-29
589 Light environment influences mating behaviours during the early stages of divergence in tropical butterflies
Hausmann, A. E.; Kuo, C.-Y.; Freire, M.; Rueda-M, N.; Linares, M.; Pardo-Diaz, C.; Salazar, C.; Merrill, R. M.
10.1101/2020.07.28.224915 — evolutionary biology — Posted on 2020-07-29
592 Citizen science, cells and CNNs - deep learning for automatic segmentation of the nuclear envelope in electron microscopy data, trained with volunteer segmentations
Spiers, H.; Songhurst, H.; Nightingale, L.; de Folter, J.; Hutchings, R.; Peddie, C. J.; Weston, A.; Strange, A.; Hindmarsh, S.; Lintott, C.; Collinson, L. M.; Jones, M. L.
10.1101/2020.07.28.223024 — cell biology — Posted on 2020-07-29
594 Heterogeneity in signaling pathway activity within primary and between primary and metastatic breast cancer
Inda, M. A.; van Swinderen, P.; van Brussel, A.; Moelans, C. B.; Veraheagh, W.; van Zon, H.; den Biezen-Timmermans, E. C.; Bikker, J. W.; van Diest, P. J.; van de Stolpe, A.
10.1101/2020.07.27.223834 — cancer biology — Posted on 2020-07-29
595 Elucidation of tumor-stromal heterogeneity and the ligand-receptor interactome by single cell transcriptomics in real-world pancreatic cancer biopsies
Lee, J. J.; Bernard, V.; Semaan, A.; Monberg, M. E.; Huang, J.; Stephens, B. M.; Lin, D.; Weston, B. R.; Bhutani, M. S.; Haymaker, C. L.; Bernatchez, C.; Taniguchi, C. M.; Maitra, A.; Guerrero, P. A.
10.1101/2020.07.28.225813 — cancer biology — Posted on 2020-07-29
596 Developing Small Molecules that Inhibit K-Ras/GTP Binding Based on New Affinity Measurements
Carta, L.; Hutcheson, R.; Davis, S. A.; Rudolph, M. J.; Reynolds, C. H.; Quick, M.; Williams, T. M.; Schmertzler, M.; Hadari, Y. R.
10.1101/2020.07.27.218248 — cancer biology — Posted on 2020-07-29
597 ImmunoPET-informed sequence for focused ultrasound-targeted mCD47 blockade controls glioma
Sheybani, N. D.; Paul, S.; McCauley, K. S.; Breza, V.; Berr, S. S.; Miller, G. W.; Neumann, K. D.; Price, R. J.
10.1101/2020.07.27.223206 — bioengineering — Posted on 2020-07-29
599 A Versatile Soluble Siglec Scaffold for Sensitive and Quantitative Detection of Glycan Ligands
Rodrigues, E.; Jung, J.; Park, H.; Loo, C.; Soukhtehzari, S.; Kitova, E. N.; Mozaneh, F.; Daskhan, G.; Aghanya, V.; Sarkar, S.; Streith, L.; St. Laurent, C.; Julien, J.-P.; West, L. C.; Williams, K. C.; Klassen, J. S.; Macauley, M. S.
10.1101/2020.07.28.223164 — biochemistry — Posted on 2020-07-29
601 Understanding hepatitis B virus dynamics and the antiviral effect of interferon-alpha treatment in humanized chimeric mice
Canini, L.; Ishida, Y.; suge, M. T.; Durso-Cain, K.; Chung, T. L.; Tateno, C.; Perelson, A. S.; Uprichard, S. L.; Chayama, K.; Dahari, H.
10.1101/2020.07.28.224840 — systems biology — Posted on 2020-07-29
602 Maize brace roots provide stalk anchorage
Reneau, J. W.; Khangura, R. S.; Stager, A.; Erndwein, L. C.; Weldekidan, T.; Cook, D. D.; Dilkes, B. P.; Sparks, E. E.
10.1101/2020.07.28.225656 — plant biology — Posted on 2020-07-29
603 A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice
Gheberemedhin, A.; Salam, A. B.; Adu-Addai, B.; Noonan, S.; Stratton, R.; Ahmed, M. S. U.; khantwal, C.; Martin, G.; Huixian, L.; Andrews, C.; Balasubramanyam, K.; Udo, R.; Henry, L.; Jaynes, J.; Yates, C.
10.1101/2020.07.27.218115 — pathology — Posted on 2020-07-29
608 Mass cytometry analysis of the NK cell receptor-ligand repertoire reveals unique differences between dengue-infected children and adults
McKechnie, J. L.; Beltran, D.; Ferreira, A.-M. M.; Vergara, R.; Saenz, L.; Vergara, O.; Estripeaut, D.; Arauz, A. B.; Simpson, L. J.; Holmes, S.; Lopez-Verges, S.; Blish, C. A.
10.1101/2020.07.27.223339 — immunology — Posted on 2020-07-29
617 Tet1 isoforms differentially regulate gene expression, synaptic transmission and memory in the mammalian brain.
Greer, C. B.; Wright, J.; Weiss, J. D.; Lazarenko, R. M.; Moran, S. P.; Zhu, J.; Chronister, K. S.; Jin, A. Y.; Kennedy, A. J.; Sweatt, J. D.; Kaas, G. A.
10.1101/2020.07.27.223685 — neuroscience — Posted on 2020-07-29
619 Co-circulation of multiple influenza A variants in swine harboring genes from seasonal human and swine influenza viruses
Ryt-Hansen, P.; Krog, J. S.; Breum, S. O.; Hjulsager, C. K.; Trebbien, R.; Pedersen, A. G.; Larsen, L. E.
10.1101/2020.07.28.225706 — microbiology — Posted on 2020-07-29
620 Insights into the catalytic properties of the mitochondrial rhomboid protease PARL
Lysyk, L.; Brassard, R.; Arutyunova, E.; Siebert, V.; Jiang, Z.; Takyi, E.; Morrison, M.; Young, H. S.; Lemberg, M. K.; O'Donoghue, A. J.; Lemieux, M. J.
10.1101/2020.07.27.224220 — biochemistry — Posted on 2020-07-29
621 Hello darkness, my old friend: 3-Ketoacyl-Coenzyme A Synthase4 is a branch point in the regulation of triacylglycerol synthesis in Arabidopsis by re-channeling fatty acids under carbon starvation
Luzarowska, U.; Russ, A.-K.; Joubes, J.; Batsale, M.; Szymanski, J. J.; Thirumalaikumar, V. P.; Luzarowski, M.; Wu, S.; Zhu, F.; Endres, N.; Khedhayir, S.; Schumacher, J.; Correa, S. M.; Skirycz, A.; Fernie, A. R.; Li-Beisson, Y.; Fusari, C. M.; Brotman, Y.
10.1101/2020.07.27.223388 — genetics — Posted on 2020-07-29
623 Rapid community-driven development of a SARS-CoV-2 tissue simulator
Getz, M.; Wang, Y.; An, G.; Becker, A.; Cockrell, C.; Collier, N.; Craig, M.; Davis, C. L.; Faeder, J.; Ford Versypt, A. N.; Gianlupi, J. F.; Glazier, J. A.; Hamis, S.; Heiland, R.; Hillen, T.; Hou, D.; Islam, M. A.; Jenner, A.; Kurtoglu, F.; Liu, B.; Macfarlane, F.; Maygrundter, P.; Morel, P.; Narayanan, A.; Ozik, J.; Pienaar, E.; Rangamani, P.; Shoemaker, J. E.; Smith, A. M.; Macklin, P.
10.1101/2020.04.02.019075 — systems biology — Posted on 2020-07-29
624 Pathogenic LRRK2 R1441C mutation is associated with striatal alterations
Xenias, H.; Chen, C.; Kang, S.; Cherian, S.; Situ, X.; Shanmugasundaram, B.; Scesa, G.; Chan, C. S.; Parisiadou, L.
10.1101/2020.03.11.986455 — neuroscience — Posted on 2020-07-29
625 Governance networks around grasslands with contrasting management history
Manolache, S.; Nita, A.; Hartel, T.; Miu, I. V.; Ciocanea, C. M.; Rozylowicz, L.
10.1101/2020.03.22.002352 — ecology — Posted on 2020-07-29
627 The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota
Bermudez-Martin, P.; Becker, J. J.; Fernandez, S. P.; Costa-Campos, R.; Barbosa, S.; Martinez Gili, L.; Myridakis, A.; Dumas, M. E.; Bruneau, A.; Cherbuy, C.; Langella, P.; Chabry, J.; Barik, J.; Le Merrer, J.; Glaichenhaus, N.; Davidovic, L.
10.1101/2020.05.18.101147 — neuroscience — Posted on 2020-07-29
628 Genomic islands of differentiation in a rapid avian radiation have been driven by recent selective sweeps
Hejase, H. A.; Salman-Minkov, A.; Campagna, L.; Hubisz, M. J.; Lovette, I. J.; Gronau, I.; Siepel, A.
10.1101/2020.03.07.977694 — evolutionary biology — Posted on 2020-07-29
630 Integrating large-scale neuroimaging research datasets: harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets
Bordin, V.; Bertani, I.; Mattioli, I.; Sundaresan, V.; McCarthy, P.; Suri, S.; Zsoldos, E.; Filippini, N.; Mahmood, A.; Melazzini, L.; Laganà, M. M.; Zamboni, G.; Singh-Manoux, A.; Kivimäki, M.; Ebmeier, K. P.; Baselli, G.; Jenkinson, M.; Mackay, C. E.; Duff, E. P.; Griffanti, L.
10.1101/2020.07.28.208579 — neuroscience — Posted on 2020-07-29
631 Loss of integration of brain networks after one night of sleep deprivation underlies worsening of attentive functions
Pesoli, M.; Rucco, R.; Liparoti, M.; Lardone, A.; D'Aurizio, G.; Minino, R.; Troisi Lopez, E.; Paccone, A.; Granata, C.; Mandolesi, L.; Sorrentino, G.; Sorrentino, P.
10.1101/2020.07.15.197590 — neuroscience — Posted on 2020-07-29
633 Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples
Kumar, V.; Mishra, S.; Sharma, R.; Agarwal, J.; Ghoshal, U.; Khanna, T.; Sharma, L. K.; Verma, S. K.; Tiwari, S.
10.1101/2020.06.30.172833 — microbiology — Posted on 2020-07-29
635 Biological control of chili damping off disease, caused by Pythium myriotylum
Hyder, S.; Gondal, A. S.; Rizvi, Z. F.; Haider, M. I. S.; Inam-ul-Haq, M.
10.1101/2020.07.28.224519 — microbiology — Posted on 2020-07-29
636 Human thymopoiesis selects unconventional CD8+ α/β T cells that respond to multiple viruses.
Quiniou, V.; Barennes, P.; Martina, F.; Mhanna, V.; Vantomme, H.; Pham, H. P.; Shugay, M.; Six, A.; Mariotti-Ferrandiz, E.; Klatzmann, D.
10.1101/2020.07.27.223354 — immunology — Posted on 2020-07-29
638 The nose is mightier than the tooth: larger male proboscis monkeys have smaller canines
Matsuda, I.; Stark, D. J.; Saldivar, D. A. R.; Tuuga, A.; Nathan, S. K. S. S.; Goossens, B.; van Schaik, C. P.; Koda, H.
10.1101/848515 — evolutionary biology — Posted on 2020-07-29
639 Among-individual diet variation within a lake trout ecotype: lack of stability of niche use.
Chavarie, L. B.; Howland, K.; Harris, L.; Gallagher, C.; Hansen, M.; Tonn, W.; Muir, A.; Krueger, C.
10.1101/811851 — ecology — Posted on 2020-07-29
641 Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate Plk1
Silva Cascales, H.; Burdova, K.; Middleton, A. W.; Kuzin, V.; Mullers, E.; Stoy, H.; Baranello, L.; Macurek, L.; Lindqvist, A.
10.1101/191437 — cell biology — Posted on 2020-07-29
642 Cavin3 released from caveolae interacts with BRCA1to regulate the cellular stress response
Parton, R. G.; McMahon, K.-A.; Stroud, D. A.; Gambin, Y.; Tillu, V.; Bastiani, M.; Sierecki, E.; Polinkovsky, M.; Hall, T. E.; Gomez, G. A.; Wu, Y.; Parat, M.-O.; Martel, N.; Lo, H. P.; Khanna, K. k.; Alexandrov, K.; Daly, R.; Yap, A. S.; Ryan, M.
10.1101/2020.07.26.222158 — cancer biology — Posted on 2020-07-29
644 PRECISE+ predicts drug response in patients by non-linear subspace-based transfer from cell lines and PDX models
Mourragui, S.; Loog, M.; Vis, D. J.; Moore, K.; Manjon, A. G.; van de Wiel, M. A.; Reinders, M. J. T.; Wessels, L. F. A.
10.1101/2020.06.29.177139 — bioinformatics — Posted on 2020-07-29
646 Leveraging phenotypic variability to identify genetic interactions in human phenotypes
Marderstein, A. R.; Davenport, E.; Kulm, S.; Van Hout, C. V.; Elemento, O.; Clark, A. G.
10.1101/2020.07.28.225730 — genetics — Posted on 2020-07-28
650 The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo
de la Rocha-Munoz, A.; Nunez, E.; Gomez-Lopez, S.; Lopez-Corcuera, B.; de Juan-Sanz, J.; Aragon, C.
10.1101/2020.07.28.224659 — neuroscience — Posted on 2020-07-28
651 Concerted but segregated actions of oxytocin and vasopressin within the ventral and dorsal lateral septum determine female aggression
Oliveira, V. E. d. M.; Lukas, M.; Wolf, H. N.; Durante, E.; Lorenz, A.; Mayer, A.-L.; Bludau, A.; Bosch, O. J.; Grinevich, V.; Egger, V.; de Jong, T. R.; Neumann, I. D.
10.1101/2020.07.28.224873 — neuroscience — Posted on 2020-07-28
653 A functional hierarchy for choice in medial prefrontal cortex
Maisson, D. J.-N.; Cash-Padgett, T. V.; Hayden, B. Y.; Heilbronner, S. R.; Zimmermann, J.
10.1101/2020.07.28.226043 — neuroscience — Posted on 2020-07-28
657 Circadian clock mechanism driving mammalian photoperiodism
Wood, S. H.; Hindle, M. H.; Mizoro, Y.; Cheng, Y.; Saer, B. R.; Miedzinska, K.; Christian, H. C.; Begley, N.; McNeilly, J.; McNeilly, A. S.; Meddle, S.; Burt, D. W.; Loudon, A. S.
10.1101/2020.05.19.102194 — molecular biology — Posted on 2020-07-28
658 Diminazene resistance in Trypanosoma congolense is linked to reduced mitochondrial membrane potential and not to reduced transport capacity
De Koning, H.; Carruthers, L. V.; Munday, J. C.; Ebiloma, G. U.; Steketee, P.; Jayaraman, S.; Campagnaro, G. D.; Ungogo, M. A.; Donachie, A.-M.; Rowan, T. G.; Peter, R.; Morrison, L. J.; Barrett, M. P.
10.1101/2020.07.28.224543 — microbiology — Posted on 2020-07-28
659 A CRISPR/Cas9 vector system for neutrophil-specific gene disruption in zebrafish
Wang, Y.; Hsu, A. Y.; Walton, E. M.; Syahirah, R.; Wang, T.; Zhou, W.; Ding, C.; Lemke, A. P.; Tobin, D. M.; Deng, Q.
10.1101/2020.07.27.223008 — genetics — Posted on 2020-07-28
663 Under pressure: phenotypic divergence and convergence associated with microhabitat adaptations in Triatominae
Abad-Franch, F.; Monteiro, F. A.; Pavan, M. G.; Patterson, J. S.; Bargues, M. D.; Zuriaga, M. A.; Aguilar, M.; Beard, C. B.; Mas-Coma, S.; Miles, M. A.
10.1101/2020.07.28.224535 — evolutionary biology — Posted on 2020-07-28
664 The calcium binding protein S100β marks Hedgehog-responsive perivascular stem cells that contribute to intimal thickening following iatrogenic flow restriction
Di Luca, M.; Fitzpatrick, E.; Burtenshaw, D.; Liu, W.; Helt, J.-C.; Hakimjavadi, R.; Corcoran, E.; Gusti, Y.; Sheridan, D.; Harman, S.; Lally, C.; Redmond, E. M.; Cahill, P. A.
10.1101/2020.05.20.105981 — cell biology — Posted on 2020-07-28
665 Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback
Lopacinski, A. B.; Sweatt, A. J.; Smolko, C. M.; Gray-Gaillard, E.; Borgmann, C. A.; Shah, M.; Janes, K. A.
10.1101/2020.07.26.222174 — systems biology — Posted on 2020-07-28
670 Human embryonic stem cells-derived dopaminergic neurons transplanted in parkinsonian monkeys recover dopamine levels and motor behavior
Lopez-Ornelas, A.; Escobedo-Avila, I.; Ramirez-Garcia, G.; Lara-Rodarte, R.; Melendez-Ramirez, C.; Urrieta-Chavez, B.; Barrios-Garcia, T.; Caceres-Chavez, V.; Flores-Ponce, X.; Carmona, F.; Reynoso, C. A.; Aguilar, C.; Kerik, N. E.; Rocha, L.; Verdugo-Diaz, L.; Trevino, V.; Bargas, J.; Ramos-Mejia, V.; Fernandez-Ruiz, J.; Campos-Romo, A.; Velasco, I.
10.1101/2020.07.08.192591 — neuroscience — Posted on 2020-07-28
672 The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in an in vitro ALS Model
Sannigrahi, A.; Chowdhury, S.; Das, B.; Banerjee, A.; Halder, A.; Naganathan, A. N.; Karmakar, S.; Chattopadhyay, K.
10.1101/2020.07.25.220962 — biophysics — Posted on 2020-07-28
675 Consideration of genetic and sex effects in mice enhances consilience with human addiction studies.
Saul, M. C.; Bagley, J. R.; Bailey, L. S.; Datta, U.; Dickson, P. E.; Dodd, R.; Gagnon, L. H.; Huggett, S. B.; Kimble, V. M.; Leonardo, M.; Kim, S.-M.; Olson, A.; Roy, T.; Schoenrock, S. E.; Wilcox, T.; Jentsch, J. D.; Logan, R. W.; McClung, C. A.; Palmer, R. H. C.; Philip, V. M.; Reinholdt, L. G.; Rizzo, S. J. S.; Tarantino, L. M.; Chesler, E. J.
10.1101/2020.02.14.949784 — neuroscience — Posted on 2020-07-28
676 Linguistic input drives brain network configuration during language comprehension.
Quinones, I.; Molinaro, N.; Caballero Gaudes, C.; Mancini, S.; Hernandez-Cabrera, J. A.; Barber, H.; Carreiras, M.
10.1101/2020.01.22.915041 — neuroscience — Posted on 2020-07-28
677 Biological control of chili damping off disease, caused by Pythium myriotylum
Gondal, A. S.; Hyder, S.; Rizvi, Z. F.; Haider, M. I. S.; Inam-ul-Haq, M.
10.1101/2020.07.28.224519 — microbiology — Posted on 2020-07-28
681 Testing theoretical minimal genomes using whole-cell models
Rees-Garbutt, J.; Rightmyer, J.; Chalkley, O.; Marucci, L.; Grierson, C.
10.1101/2020.03.26.010363 — synthetic biology — Posted on 2020-07-28
682 Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness
Sanz Perl, Y.; Pallavicini, C.; Ipina, I. P.; Demertzi, A.; Bonhomme, V.; Martial, C.; Panda, R.; Annen, J.; Ibanez, A.; Kringelbach, M.; Deco, G.; Laufs, H.; Sitt, J.; Laureys, S.; Tagliazucchi, E.
10.1101/2020.07.02.185157 — neuroscience — Posted on 2020-07-28
687 Identification of clinical combination therapies to induce durable responses in kidney cancers
Lue, H.-w.; Derrick, D. S.; Rao, S.; VanGaest, A.; Cheng, L.; Podolak, J.; Lawson, S.; Xue, C.; Garg, D.; White, R.; Ryan, C. W.; Drake, J. M.; Ritz, A.; Heiser, L. M.; Thomas, G. V.
10.1101/2020.07.25.221507 — cancer biology — Posted on 2020-07-28
688 Weak catch bonds make strong networks
Mulla, Y.; Avellaneda, M. J.; Roland, A.; Baldauf, L.; Tans, S. J.; Koenderink, G.
10.1101/2020.07.27.219618 — biophysics — Posted on 2020-07-28
690 A scientometric overview of CORD-19
Colavizza, G.; Costas, R.; Traag, V. A.; van Eck, N. J.; van Leeuwen, T.; Waltman, L.
10.1101/2020.04.20.046144 — scientific communication and education — Posted on 2020-07-28
691 Altered stomatal patterning accompanies a trichome dimorphism in a natural population of Arabidopsis
Simon, N. M.; Sugisaka, J.; Honjo, M. N.; Aarseth Tunstad, S.; Tunna, G.; Kudoh, H.; Dodd, A. N.
10.1101/710889 — plant biology — Posted on 2020-07-28
692 Gut Microbiota Mediates High-Fiber Diet Alleviation of Maternal Obesity-Induced Cognitive and Social Deficits in Offspring
Liu, X.; Li, X.; Xia, B.; Jin, X.; Zeng, Z.; Yan, S.; Li, L.; Yuan, S.; Zhao, S.; Dai, X.; Yin, F.; Cadenas, E.; Liu, R. H.; Zhao, B.; Hou, M.; Liu, Z.; Liu, X.
10.1101/2020.07.16.206714 — neuroscience — Posted on 2020-07-28
695 Immune factor of bacterial origin protects ticks against host microbial commensals
Hayes, B. M.; Radkov, A. D.; Yarza, F.; Flores, S.; Kim, J. R.; Zhao, Z.; Lexa, K. W.; Marnin, L.; Biboy, J.; Bowcutt, V.; Vollmer, W.; Pedra, J. H.; Chou, S.
10.1101/2020.04.10.036376 — evolutionary biology — Posted on 2020-07-28
696 Pathogenic mutations in LRRK2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
Mamais, A.; Landeck, N.; Langston, R. G.; Bonet-Ponce, L.; Smith, N.; Beilina, A.; Kaganovich, A.; Ghosh, M. C.; Pellegrini, L.; Kluss, J. H.; Kumaran, R.; Papazoglou, I.; Maio, N.; Kim, C.; Gershlick, D. C.; Cookson, M. R.
10.1101/2020.07.27.219501 — cell biology — Posted on 2020-07-28
699 Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release
Ijäs, H.; Shen, B.; Heuer-Jungemann, A.; Keller, A.; Kostiainen, M. A.; Liedl, T.; Ihalainen, J. A.; Linko, V.
10.1101/2020.05.13.088054 — biochemistry — Posted on 2020-07-28
701 Clathrin light chain diversity regulates membrane deformation in vitro and synaptic vesicle formation in vivo
Redlingshoefer, L.; McLeod, F.; Chen, Y.; Camus, M. D.; Burden, J. J.; Palomer, E.; Briant, K.; Dannhauser, P. N.; Salinas, P. C.; Brodsky, F.
10.1101/815183 — cell biology — Posted on 2020-07-28
704 Systemic inflammation causes microglial dysfunction with a mixed AD-like pathology.
Bathini, P.; Dupanloup, I.; Zenaro, E.; Terrabuio, E.; Ballabani, E.; Fischer, A.; Doucey, M.-A.; Alberi, L.
10.1101/2020.07.27.223198 — neuroscience — Posted on 2020-07-28
705 Natural Antisense Transcript of Period2, Per2AS, regulates the amplitude of the mouse circadian clock
Mosig, R. A.; Castaneda, A. N.; Deslauriers, J. C.; Frazier, L. P.; He, K. L.; Maghzian, N.; Pokharel, A.; Schrier, C. T.; Zhu, L.; Koike, N.; Tyson, J. J.; Green, C. B.; Takahashi, J. S.; Kojima, S.
10.1101/2020.07.27.222760 — molecular biology — Posted on 2020-07-28
706 Recent evolutionary history of tigers highlights contrasting roles of genetic drift and selection
Armstrong, E.; Khan, A.; Taylor, R. W.; Gouy, A.; Greenbaum, G.; Thiery, A.; Kang, J. T.; Redondo, S. A.; Prost, S.; Barsh, G.; Kaelin, C.; Phalke, S.; Chugani, A.; Gilbert, M.; Miquelle, D.; Zachariah, A.; Borthakur, U.; Reddy, A.; Louis, E.; Ryder, O.; Jhala, Y.; Petrov, D.; Excoffier, L.; Hadly, E.; Ramakrishnan, U.
10.1101/696146 — genomics — Posted on 2020-07-28
710 IlvY is an important regulator of Shigella infection in vitro and in vivo
Holly, M. K.; Anderson, M. C.; Rabago, L. M.; Saffarian, A.; Marteyn, B. S.; Arnold, S. L. M.
10.1101/2020.07.28.220327 — microbiology — Posted on 2020-07-28
711 Proteomic and Transcriptomic Analyses of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Cases
Leitner, D. F.; Mills, J. D.; Pires, G.; Faustin, A.; Drummond, E.; Kanshin, E.; Nayak, S.; Askenazi, M.; Verducci, C.; Chen, B. J.; Janitz, M.; Anink, J. J.; Baayen, J. C.; Idema, S.; van Vliet, E. A.; Devore, S.; Friedman, D.; Diehl, B. V.; Scott, C.; Thijs, R.; Wisniewski, T.; Ueberheide, B.; Thom, M.; Aronica, E.; Devinsky, O.
10.1101/2020.07.27.223446 — neuroscience — Posted on 2020-07-28
717 Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus
Wang, S.; Reeve, S. M.; Ojewole, A. A.; Frenkel, M. S.; Holt, G. T.; Gainza, P.; Keshipeddy, S.; Fowler, V. G.; Wright, D. L.; Donald, B. R.
10.1101/2020.07.28.224667 — biochemistry — Posted on 2020-07-28
718 Crystal structure of schizorhodopsin reveals mechanism of inward proton pumping
Higuchi, A.; Shihoya, W.; Konno, M.; Ikuta, T.; Kandori, H.; Inoue, K.; Nureki, O.
10.1101/2020.07.28.224907 — biochemistry — Posted on 2020-07-28
721 Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate
Sun, W.; Leist, S. R.; McCroskery, S.; Liu, Y.; Slamanig, S.; Oliva, J.; Amanat, F.; Schaefer, A.; Dinnon, K.; Garcia-Sastre, A.; Krammer, F.; Baric, R. S.; Palese, P.
10.1101/2020.07.26.221861 — microbiology — Posted on 2020-07-28
722 Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
Tandon, R.; Sharp, J. S.; Zhang, F.; Pomin, V. H.; Ashpole, N. M.; Mitra, D.; Jin, W.; Liu, H.; Sharma, P.; Linhardt, R. J.
10.1101/2020.06.08.140236 — microbiology — Posted on 2020-07-28
723 The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocytes and lung epithelial cells, decrease the production of proinflammatory cytokines, and VIP levels are associated with survival in severe Covid-19 patients.
Temerozo, J. R.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Pao, C. R. R.; de Freitas, C. S.; Dias, S. d. S. G.; Ferreira, A. C.; Mattos, M.; Soares, V. C.; Teixeira, L.; de Azevedo-Quintanilha, I. G.; Kurtz, P.; Bozza, F. A.; Bozza, P. T.; Souza, T. M. L.; Bou-Habib, D. C.
10.1101/2020.07.25.220806 — microbiology — Posted on 2020-07-28
727 Intersection of structural and functional connectivity of the nucleus basalis of Meynert in Parkinson's disease dementia and Lewy body dementia
Oswal, A.; gratwicke, j.; Akram, H.; Jahanshahi, M.; Zaborszky, L.; Brown, P.; Hariz, M.; Zrinzo, L.; Foltynie, T.; Litvak, V.
10.1101/2020.07.27.221853 — neuroscience — Posted on 2020-07-28
728 Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories
Su, Y.; Chen, D.; Lausted, C.; Yuan, D.; Choi, J.; Dai, C.; Voillet, V.; Scherler, K.; Troisch, P.; Duvvuri, V. R.; Baloni, P.; Qin, G.; Smith, B.; Kornilov, S.; Rostomily, C.; Xu, A.; Li, J.; Dong, S.; Rothchild, A.; Zhou, J.; Murray, K.; Edmark, R.; Hong, S.; Jones, L.; Zhou, Y.; Roper, R.; Mackay, S.; O'Mahony, D. S.; Dale, C. R.; Wallick, J. A.; Algren, H. A.; Michael, Z. A.; Magis, A.; Wei, W.; Price, N. D.; Huang, S.; Subramanian, N.; Wang, K.; Hadlock, J.; Hood, L.; Aderem, A.; Bluestone, J. A.; Lanier, L. L.; Greenberg, P.; Gottardo, R.; Davis, M. M.; Goldman, J. D.; Heath, J. R.; the
10.1101/2020.07.27.224063 — immunology — Posted on 2020-07-28
730 HIT-scISOseq: High-throughput and High-accuracy Single-cell Full-length Isoform Sequencing for Corneal Epithelium
Zheng, Y.-F.; Chen, Z.-C.; Shi, Z.-X.; Hu, K.-H.; Zhong, J.-Y.; Wang, C.-X.; Shi, W.; Chen, Y.; Xie, S.-Q.; Luo, F.; Bo, X.; Tang, C.; Liu, Y.-Z.; Xiao, C.-L.
10.1101/2020.07.27.222349 — genomics — Posted on 2020-07-28
731 Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells
FOLLAIN, G.; OSMANI, N.; MERCIER, L.; GARCIA-LEON, M. J.; BUSNELLI, I.; PICHOT, A.; PAUL, N.; CARAPITO, R.; BAHRAM, S.; LEFEBVRE, O.; GOETZ, J. G.
10.1101/2020.07.27.219568 — cancer biology — Posted on 2020-07-28
733 Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism
Jacob, F.; Pather, S.; Huang, W.-K.; Wong, S. Z. H.; Zhou, H.; Zhang, F.; Cubitt, B.; Chen, C. Z.; Xu, M.; Pradhan, M.; Zhang, D. Y.; Zheng, W.; Bang, A. G.; Song, H.; de la Torre, J. C.; Ming, G.-l.
10.1101/2020.07.28.225151 — neuroscience — Posted on 2020-07-28
741 A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors
Liu, W. R.; Yang, K. S.; Ma, X. R.; Ma, Y.; Alugubelli, Y. R.; Scott, D. A.; Vatansever, E. C.; Drelich, A. K.; Geng, Z. Z.; Blankenship, L. R.; Sankaran, B.; Ward, H. E.; Sheng, Y. J.; Hsu, J. C.; Kratch, K. K.; Zhao, B.; Liu, J.; Li, P.; Fierke, C. A.; Tseng, C.-T. K.; Xu, S.; Hayatshahi, H. S.
10.1101/2020.07.28.223784 — biochemistry — Posted on 2020-07-28
742 Changes in salt-marsh vegetation weakly affect top consumers of aquatic food webs
Lafage, D.; Carpentier, A.; Duhamel, S.; Dupuy, C.; Feunteun, E.; Lesourd, S.; Petillon, J.
10.1101/2020.07.27.222406 — ecology — Posted on 2020-07-28
743 Pyronaridine and artesunate are potential antiviral drugs against COVID-19 and influenza
Bae, J.-Y.; Lee, G. E.; Park, H.; Cho, J.; Kim, Y.-E.; Lee, J.-Y.; Ju, C.; Kim, W.-K.; Kim, J. I.; Park, M.-S.
10.1101/2020.07.28.225102 — microbiology — Posted on 2020-07-28
744 Antibodies that potently inhibit or enhance SARS-CoV-2 spike protein-ACE2 interaction isolated from synthetic single-chain antibody libraries
Beasley, M. D.; Aracic, S.; Gracey, F. M.; Kannan, R.; Masarati, A.; Premaratne, S. R.; Udawela, M.; Wood, R. E.; Jabar, S.; Church, N.; Le, T.-K.; Makris, D.; McColl, B. K.; Kiefel, B. R.
10.1101/2020.07.27.224089 — immunology — Posted on 2020-07-28
745 Tryptophan residues in TDP-43 and SOD1 mediate the cross-seeding and toxicity of SOD1
Pokrishevsky, E.; Duval, M. G.; McAlary, L.; Louadi, S.; Pozzi, S.; Roman, A. Y.; Plotkin, S. S.; Dijkstra, A.; Julien, J.-P.; Allison, W. T.; Cashman, N. R.
10.1101/2020.07.27.224188 — cell biology — Posted on 2020-07-28
746 Poly(ADP-ribose)-binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions
Kumbhar, R. R.; Perren, J.; Gong, F.; Corujo, D.; Medina, F.; Matouschek, A.; Buschbeck, M.; Miller, K. M.
10.1101/2020.07.27.223131 — cell biology — Posted on 2020-07-28
747 Lamin C regulates genome organization after mitosis
Wong, X.; Hoskins, V. E.; Harr, J. C.; Gordon, M.; Reddy, K.
10.1101/2020.07.28.213884 — cell biology — Posted on 2020-07-28
752 Feeling the beat: Temporal and spatial perception of heartbeat sensations
betka, s.; Lukowska, M.; Silva, M.; king, j.; Garfinkel, S.; Critchley, H.
10.1101/2020.07.27.222810 — neuroscience — Posted on 2020-07-28
758 Genome-Wide Mapping of Cisplatin Damaged Gene Loci
Qi, L.; Luo, Q.; Xu, Y.; Yu, W.; Liu, X.; Zhang, Y.; Jia, F.; Fang, T.; Wang, S.; Li, X.; Zhao, Y.; Wang, F.
10.1101/2020.07.27.222752 — pharmacology and toxicology — Posted on 2020-07-28
760 The ABCD Stop Signal Data: Response to Bissett et al.
Garavan, H.; Hahn, S.; Chaarani, B.; Juliano, A.; Allgaier, N.; Yuan, D. K.; Weigard, A.; Orr, C.; Watts, R.; Wager, T.; Ruiz de Leon, O.; Hagler, D.; Potter, A.
10.1101/2020.07.27.223057 — neuroscience — Posted on 2020-07-28
762 Modelling white matter in gyral blades as a continuous vector field
Cottaar, M.; Bastiani, M.; Boddu, N.; Glasser, M. F.; Haber, S.; Van Essen, D. C.; Sotiropoulos, S. N.; Jbabdi, S.
10.1101/2020.07.27.222778 — neuroscience — Posted on 2020-07-28
772 Oncogenic gene fusions in non-neoplastic precursors as evidence that bacterial infection initiates prostate cancer
Shrestha, E.; Coulter, J.; Guzman, W.; Ozbek, B.; Mummert, L.; Ernst, S.; Maynard, J.; Meeker, A.; Heaphy, C.; Haffner, M.; De Marzo, A. M.; Sfanos, K. S.
10.1101/2020.07.27.224154 — cancer biology — Posted on 2020-07-28
774 Ocular Dominance Plasticity: Measurement Reliability and Variability
Min, S. H.; Gong, L.; Baldwin, A. S.; Reynaud, A.; He, Z.; Zhou, J.; Hess, R. F.
10.1101/2020.07.27.211144 — neuroscience — Posted on 2020-07-28
775 Hybrid optogenetic and electrical stimulation for greater spatial resolution and temporal fidelity of cochlear activation
Thompson, A. C.; Wise, A. K.; Hart, W. L.; Needham, K.; Fallon, J. B.; Gunewardene, N.; Stoddart, P. R.; Richardson, R. T.
10.1101/2020.07.27.187294 — neuroscience — Posted on 2020-07-28
776 Combinatorial CRISPR screening reveals functional buffering in autophagy
Diehl, V.; Wegner, M.; Grumati, P.; Husnjak, K.; Schaubeck, S.; Gubas, A.; Shah, V. J.; Langschied, F.; Kalousi, A.; Ebersberger, I.; Dikic, I.; Kaulich, M.
10.1101/2020.07.28.201152 — cell biology — Posted on 2020-07-28
779 NBS1-CtIP-Mediated DNA End Resection Regulates cGAS Binding to Micronuclei
Abdisalaam, S.; Mukherjee, S.; Bhattacharya, S.; Sinha, D.; Kumari, S.; Sadek, H. A.; Ortega, J.; Li, G.-M.; Aroumougame, A.
10.1101/2020.07.27.222380 — immunology — Posted on 2020-07-28
780 Bro1 directly stimulates Vps4 activity to promote Intralumenal Vesicle Formation during Multivesicular Body biogenesis
Katzmann, D.; Tseng, C.-c.; Dean, S.; Davies, B. A.; Azmi, I. F.; Pashkova, N.; Payne, J. A.; Staffenhagen, J.; West, M.; Piper, R. C.; Odorizzi, G.
10.1101/2020.07.27.223255 — cell biology — Posted on 2020-07-28
782 Tumor-stromal IL1β/ NFκB / ESE3 Signal Axis Drives Pancreatic Cancer Fibrosis, Chemoresistance, Prognosis
Hao, J.; Zhao, T.; Xiao, D.; Jin, F.; Wang, H.; Liu, J.; Cai, W.; Huang, C.; Wang, X.; Gao, S.; Yang, S.
10.1101/2020.07.27.222455 — cancer biology — Posted on 2020-07-28
784 Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
Hsia, Y.; Mout, R.; Sheffler, W.; Edman, N. I.; Vulovic, I.; Park, Y.-J.; Redler, R. L.; Bick, M. J.; Bera, A. K.; Courbet, A.; Kang, A.; Brunette, T.; Nattermann, U.; Tsai, E.; Saleem, A.; Chow, C. M.; Ekiert, D. C.; Bhabha, G.; Veesler, D.; Baker, D.
10.1101/2020.07.27.221333 — biochemistry — Posted on 2020-07-28
786 Development of a small molecule that corrects misfolding and increases secretion of Z α1-antitrypsin
Lomas, D.; Irving, J. A.; Arico-Muendel, C.; Belyanskaya, S.; Brewster, A.; Brown, M. J. B.; Chung, C.-w.; Dave, H.; Denis, A.; Dodic, N.; Dossang, A.; Eddershaw, P.; Klimaszewska, D.; Haq, I.; Holmes, D.; Hutchinson, J.; Jagger, A. M.; Jakhria, T.; Jigorel, E.; Liddle, J.; Lind, K.; Marciniak, S. J.; Messer, J.; Neu, M.; Olszewski, A.; Ordonez, A.; Ronzoni, R.; Rowedder, J.; Rüdiger, M.; Skinner, S.; Smith, K.; Terry, R.; Trottet, L.; Uings, I.; Wilson, S.; Zhu, Z.; Pearce, A. C.
10.1101/2020.07.26.217661 — pharmacology and toxicology — Posted on 2020-07-28
790 Pili allow dominant marine cyanobacteria to avoid sinking and evade predation
Christie-Oleza, J.; Aguilo-Ferretjans, M. d. M.; Bosch, R.; Puxty, R. J.; Latva, M.; Zadjelovic, V.; Chhun, A.; Sousoni, D.; Polin, M.; Scanlan, D.
10.1101/2020.07.09.194837 — microbiology — Posted on 2020-07-27
791 Novel algorithms for PFGE bacterial typing: Number of co-migrated DNA fragments, linking PFGE to WGS results and computer simulations for evaluation of PulseNet international typing protocols
Adam, I. E.-k. M.; Abdokashif, I.; Elrashid, A.; Bayoumi, H.; Musa, A.; Abdulgyom, E.; Mamoun, S.; Alnagar, S.; Mohammed, W.; El-khateeb, A.; Oshi, M.; El-bakri, F.
10.1101/2020.07.05.188623 — bioinformatics — Posted on 2020-07-27
792 Modal properties of fruit-rachilla system of the macaw palm
Villar, F. M. d. M.; Pinto, F. d. A. d. C.; Santos, F. L.; Queiroz, D. M. d.; Pereira, M. R.; Magalhaes Valente, D. S.
10.1101/2020.07.27.222687 — bioengineering — Posted on 2020-07-27
793 Genome wide identification of QTL associated with yield and yield components in two popular wheat cultivars TAM 111 and TAM 112
Yang, Y.; Dhakal, S.; Chu, C.; Wang, S.; Xue, Q.; Rudd, J. C.; Ibrahim, A. M. H.; Jessup, K.; Baker, J.; Fuentealba, M. P.; Devkota, R.; Johnson, C. D.; Metz, R.; Baker, S.; Baker, S.
10.1101/2020.07.27.222703 — genetics — Posted on 2020-07-27
794 First evidence for an aposematic function of a very common color pattern in small insects.
Mora-Castro, R.; Alfaro-Cordoba, M.; Hernandez-Jimenez, M.; Fernandez Otarola, M.; Mendez-Rivera, M.; Ramirez-Morales, D.; Rodriguez-Rodriguez, C. E.; Duran-Rodriguez, A.; Hanson, P. E.
10.1101/2020.07.27.222653 — animal behavior and cognition — Posted on 2020-07-27
796 The Mouse Action Recognition System (MARS): a software pipeline for automated analysis of social behaviors in mice
Segalin, C.; Williams, J.; Karigo, T.; Hui, M.; Zelikowsky, M.; Sun, J. J.; Perona, P.; Anderson, D. J.; Kennedy, A.
10.1101/2020.07.26.222299 — neuroscience — Posted on 2020-07-27
797 Enhanced Brain Imaging Genetics in UK Biobank
Smith, S. M.; Douaud, G.; Chen, W.; Hanayik, T.; Alfaro-Almagro, F.; Sharp, K.; Elliott, L. T.
10.1101/2020.07.27.223545 — neuroscience — Posted on 2020-07-27
799 An aberrant cytoplasmic intron retention programme is a blueprint for ALS-related RBP mislocalization
Tyzack, G. E.; Neeves, J.; Klein, P.; Crerar, H.; Ziff, O.; Taha, D. M.; Luisier, R.; Luscombe, N. M.; Patani, R.
10.1101/2020.07.20.211557 — neuroscience — Posted on 2020-07-27
801 Class A Penicillin-Binding Protein-mediated cell wall synthesis promotes structural integrity during peptidoglycan endopeptidase insufficiency
Murphy, S. G.; Murtha, A. N.; Zhao, Z.; Alvarez, L.; Diebold, P.; Shin, J.-H.; VanNieuwenhze, M. S.; Cava, F.; Doerr, T.
10.1101/2020.07.03.187153 — microbiology — Posted on 2020-07-27
803 dN/dS dynamics quantify tumour immunogenicity and predict response to immunotherapy
Zapata, L.; Caravagna, G.; Williams, M.; Lakatos, E.; Abdul-Jabbar, K.; Werner, B.; Graham, T. A.; Sottoriva, A.
10.1101/2020.07.21.215038 — genomics — Posted on 2020-07-27
807 Massive-scale biological activity-based modeling identifies novel antiviral leads against SARS-CoV-2
Huang, R.; Xu, M.; Zhu, H.; Chen, C. Z.; Lee, E.; He, S.; Shamim, K.; Bougie, D.; Huang, W.; Hall, M.; Lo, D.; Simeonov, A.; Austin, C.; Qiu, X.; Tang, H.; Zheng, W.
10.1101/2020.07.27.223578 — cell biology — Posted on 2020-07-27
811 A novel ultrasound-guided mouse model of sudden cardiac arrest
Rutledge, C. A.; Chiba, T.; Redding, K.; Dezfulian, C.; Simms-Lucas, S.; Kaufman, B. A.
10.1101/2020.07.27.222695 — physiology — Posted on 2020-07-27
813 Intrathecal catheter implantation decreases cerebrospinal fluid dynamics in cynomolgus monkeys
Martin, B. A.; Khani, M.; Fu, A. Q.; Pluid, J.; Gibbs, C. P.; Oshinski, J. N.; Xing, T.; Stewart, G. R.; Zeller, J. R.
10.1101/2020.07.27.222646 — pharmacology and toxicology — Posted on 2020-07-27
814 Modulation of proteasome activity by curcumin and didemethylcurcumin
Khan, T. K.; You, Y.; Nelson, T.; Kundu, S.; Pramanik, S.; Das, J. J.
10.1101/2020.07.27.222679 — neuroscience — Posted on 2020-07-27
816 A Conserved TCRβ signature dominates a highly polyclonal T-cell expansion during the acute phase of a murine malaria infection
Smith, N. L.; Nahrendorf, W.; Sutherland, C.; Mooney, J. P.; Thompson, J.; Spence, P. J.; Cowan, G. J. M.
10.1101/2020.07.27.222570 — immunology — Posted on 2020-07-27
818 Neuronal SKN-1B Modulates Nutritional Signalling Pathways and Mitochondrial Networks to Control Satiety
Tataridas-Pallas, N.; Thompson, M. A.; Howard, A.; Brown, I.; Ezcurra, M.; Wu, Z.; Kuerten, T.; Goncalves Silva, I.; Blackwell, T. K.; Tullet, J. M. A.
10.1101/2020.07.21.213504 — genetics — Posted on 2020-07-27
820 Cell-free DNA as a biomarker for prostate cancer: elevated concentration and decreased fragment size
Chen, E.; Cario, C. L.; Leong, L.; Lopez, K.; Marquez, C.; Chu, C.; Li, P. S.; Oropeza, E.; Tenggara, I.; Cowan, J.; Simko, J. P.; Chan, J. M.; Friedlander, T.; Wyatt, A. W.; Aggarwal, R.; Paris, P. L.; Carroll, P. R.; Feng, F.; Witte, J. S.
10.1101/2020.07.26.215020 — cancer biology — Posted on 2020-07-27
823 Modeling Alpha-Synuclein Pathology in a Human Brain-Chip to Assess Blood-Brain Barrier Disruption in Parkinson's Disease
Pediaditakis, I.; Kodella, K. R.; Manatakis, D. V.; Hinojosa, C. D.; Manolakos, E. S.; Rubin, L. L.; Hamilton, G. A.; Karalis, K.
10.1101/2020.07.22.207340 — bioengineering — Posted on 2020-07-27
825 An integrated, modular approach to data science education in the life sciences
Dill-McFarland, K. A.; Koenig, S. G.; Mazel, F.; Oliver, D.; McEwen, L. M.; Hong, K. Y.; Hallam, S. J.
10.1101/2020.07.25.218453 — scientific communication and education — Posted on 2020-07-27
834 Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degrading enzyme, in brain
Nilsson, P.; Sorgjerd, K.; Kakiya, N.; Sasaguri, H.; Watamura, N.; Shimozawa, M.; Tsubuki, S.; Takamura, R.; Zhou, Z.; Loera-Valencia, R.; Sekiguchi, M.; Petrish, A.; Schulz, S.; Saito, T.; Winblad, B.; Saido, T.
10.1101/2020.05.09.085795 — neuroscience — Posted on 2020-07-27
835 A genome-wide CRISPR/Cas phenotypic screen formodulators of DUX4 cytotoxicity reveals screen complications
Ashoti, A.; Limone, F.; van Kranenburg, M.; Alemany, A.; Baak, M.; Vivie, J.; Piccioni, F.; Creyghton, M.; Eggan, K.; Geijsen, N.
10.1101/2020.07.27.223420 — molecular biology — Posted on 2020-07-27
838 The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus
Washington, J. T.; Cavender, K. R.; Amukamara, A. U.; McKinney, E. C.; Schmitz, R. J.; Moore, P. J.
10.1101/2020.07.23.218180 — evolutionary biology — Posted on 2020-07-27
839 Niche and neutral processes leave distinct structural imprints on indirect interactions in mutualistic networks
Simmons, B. I.; Beckerman, A. P.; Hansen, K.; Maruyama, P. K.; Televantos, C.; Vizentin-Bugoni, J.; Dalsgaard, B.
10.1101/2020.04.30.070391 — ecology — Posted on 2020-07-27
840 EHBP1 and EHD2 regulate Dll4 caveolin-mediated endocytosis during blood vessel development
Webb, A. M.; Francis, C. R.; Webb, J. M.; Kincross, H.; Lundy, K. M.; Judson, R.; Meadows, S. M.; Kushner, E. J.
10.1101/2020.05.19.104547 — cell biology — Posted on 2020-07-27
844 A way to break bones? The weight of intuitiveness
Vettese, D.; Stavrova, T.; Borel, A.; Marin, J.; Moncel, M.-H.; Arzarello, M.; Daujeard, C.
10.1101/2020.03.31.011320 — paleontology — Posted on 2020-07-27
851 Structural characterization of covalently stabilized human cystatin C oligomers
Chrabaszczewska, M.; Sieradzan, A. K.; Rodziewicz-Motowidło, S.; Grubb, A.; Dobson, C. M.; Kumita, J. R.; Kozak, M.
10.1101/654772 — biophysics — Posted on 2020-07-27
852 Plasma non-esterified fatty acids contribute to increased coagulability in type-2 diabetes through altered plasma zinc speciation
Sobczak, A. I. S.; Katundu, K. G. H.; Phoenix, F. A.; Khazaipoul, S.; Yu, R.; Lampiao, F.; Stefanowicz, F.; Blindauer, C. A.; Pitt, S. J.; Smith, T. K.; Ajjan, R. A.; Stewart, A. J.
10.1101/744482 — biochemistry — Posted on 2020-07-27
853 Flagellar structures from the bacterium Caulobacter crescentus and implications for phage {Phi}CbK predation of multi-flagellin bacteria
Montemayor, E. J.; Ploscariu, N. T.; Sanchez, J. C.; Parrell, D.; Dillard, R. S.; Shebelut, C. W.; Ke, Z.; Guerrero-Ferreira, R. C.; Wright, E. R.
10.1101/2020.07.27.223248 — microbiology — Posted on 2020-07-27
855 LOK/SLK kinases and ERM proteins function together to regulate apical morphology and inhibit RhoA signaling
Zaman, R.; Lombardo, A. T.; Sauvanet, C.; Viswanatha, R.; Awad, V.; Bonomo, L. E.; McDermitt, D. J.; Bretscher, A. P.
10.1101/2020.07.02.185298 — cell biology — Posted on 2020-07-27
860 Evolution And Genetic Diversity Of SARSCoV-2 In Africa Using Whole Genome Sequences
Motayo, B. O.; Oluwasemowo, O. O.; Akinduti, P. A.; Olusola, B. A.; Arege, O. T.; Faneye, A. O.
10.1101/2020.07.27.222901 — microbiology — Posted on 2020-07-27
861 An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain
Wu, N. C.; Yuan, M.; Liu, H.; Lee, C.-C. D.; Zhu, X.; Bangaru, S.; Torres, J. L.; Caniels, T. G.; Brouwer, P. J. M.; van Gils, M. J.; Sanders, R. W.; Ward, A. B.; Wilson, I. A.
10.1101/2020.07.26.222232 — microbiology — Posted on 2020-07-27
863 Low-cost 3D-printed inverted microscope to detect Mycobacterium tuberculosis in a MODS culture
Salguedo, M. I.; Zarate, G. W.; Gilman, R.; Comina, G.; Coronel, J.; Sheen, P.; Zimic, M.
10.1101/2020.07.27.223701 — microbiology — Posted on 2020-07-27
865 Establishing live-cell single-molecule localization microscopy imaging and single-particle tracking in the archaeon Haloferax volcanii
Turkowyd, B.; Schreiber, S.; Wörtz, J.; Shtifman Segal, E.; Mevarech, M.; Duggin, I. G.; Marchfelder, A.; Endesfelder, U.
10.1101/2020.07.27.222935 — microbiology — Posted on 2020-07-27
869 Polycomb-mediated Genome Architecture Enables Long-range Spreading of H3K27 methylation
Kraft, K.; Yost, K. E.; Murphy, S.; Magg, A.; Long, Y.; Corces, R. M.; Granja, J. M.; Mundlos, S.; Cech, T. R.; Boettiger, A.; Chang, H. Y.
10.1101/2020.07.27.223438 — genetics — Posted on 2020-07-27
871 Opposing modulation of Cx26 gap junctions and hemichannels by CO2
Nijjar, S.; Maddison, D.; Meigh, L.; de Wolf, E.; Rodgers, T.; Cann, M. J.; Dale, N.
10.1101/584722 — cell biology — Posted on 2020-07-27
872 Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L
Sacco, M. D.; Ma, C.; Lagarias, P.; Gao, A.; Townsend, J. A.; Meng, X.; Dube, P.; Zhang, X.; Hu, Y.; Kitamura, N.; Hurst, B.; Tarbet, B.; Marty, M. T.; Kolocouris, A.; Xiang, Y.; Chen, Y.; Wang, J.
10.1101/2020.07.27.223727 — biophysics — Posted on 2020-07-27
874 Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with an endemic human CoV
Ladner, J. T.; Henson, S. N.; Boyle, A. S.; Engelbrektson, A. L.; Fink, Z. W.; Rahee, F.; D'ambrozio, J.; Schaecher, K. E.; Stone, M.; Dong, W.; Dadwal, S.; Yu, J.; Caligiuri, M. A.; Cieplak, P.; Bjoras, M.; Fenstad, M. H.; Nordbo, S. A.; Kainov, D. E.; Muranaka, N.; Chee, M. S.; Shiryaev, S. A.; Altin, J. A.
10.1101/2020.07.27.222943 — immunology — Posted on 2020-07-27
875 CAR Macrophages for SARS-CoV-2 Immunotherapy
Fu, W.; Lei, C.; Qian, K.; Ma, Z.; Li, T.; Lin, F.; Zhao, J.; Hu, S.
10.1101/2020.07.26.222208 — bioengineering — Posted on 2020-07-27
878 Targeting the endolysosomal host-SARS-CoV-2 interface by the clinically licensed antidepressant fluoxetine
Schloer, S.; Brunotte, L.; Goretzko, J.; Mecate-Zambrano, A.; Korthals, N.; Gerke, V.; Ludwig, S.; Rescher, U.
10.1101/2020.07.27.222836 — microbiology — Posted on 2020-07-27
879 Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals
Doddapaneni, H. V.; Cregeen, S. J.; Sucgang, R.; Meng, Q.; Qing, X.; Avadhanula, V.; Chao, H.; Menon, V.; Nicholson, E.; Henke, D.; Piedra, F.-A.; Rajan, A.; Momin, Z.; Kottapalli, K.; Hoffman, K. L.; Sedlazeck, F. J.; Metcalf, G.; Piedra, P. A.; Muzny, D. M.; Petrosino, J. F.; Gibbs, R. A.
10.1101/2020.07.27.223495 — microbiology — Posted on 2020-07-27
882 Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures
Salahudeen, A. A.; Choi, S. S.; Rustagi, A.; Zhu, J.; de la O, S. M.; Flynn, R. A.; Margalef-Catala, M.; Santos, A. J. M.; Ju, J.; Batish, A.; van Unen, V.; Usui, T.; Zheng, G. X. Y.; Edwards, C. E.; Wagar, L. E.; Luca, V.; Anchang, B.; Nagendran, M.; Nguyen, K.; Hart, D. J.; Terry, J. M.; Belgrader, P.; Ziraldo, S. B.; Mikkelsen, T. S.; Harbury, P. B.; Glenn, J. S.; Garcia, K. C.; Davis, M. M.; Baric, R. S.; Sabatti, C.; Amieva, M. R.; Blish, C. A.; Desai, T. J.; Kuo, C. J.
10.1101/2020.07.27.212076 — cell biology — Posted on 2020-07-27
883 Bepridil is Potent Against SARS-CoV-2 In Vitro
Vatansever, E. C.; Yang, K. S.; Kratch, K. C.; Drelich, A.; Cho, C.-C.; Mellott, D. M.; Xu, S.; Tseng, C.-T. K.; Liu, W. R.
10.1101/2020.05.23.112235 — pharmacology and toxicology — Posted on 2020-07-27
884 The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocytes and lung epithelial cells, decrease production of proinflammatory cytokines, and VIP levels are associated with survival in severe Covid-19 patients.
Temerozo, J. R.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Pao, C. R. R.; de Freitas, C. S.; Dias, S. d. S. G.; Ferreira, A. C.; Mattos, M.; Soares, V. C.; Teixeira, L.; de Azevedo-Quintanilha, I. G.; Kurtz, P.; Bozza, F. A.; Bozza, P. T.; Souza, T. M. L.; Bou-Habib, D. C.
10.1101/2020.07.25.220806 — microbiology — Posted on 2020-07-27
888 Identification, Mapping and Relative Quantitation of SARS-CoV-2 Spike Glycopeptides by Mass-Retention Time Fingerprinting
Chalk, R.; Greenland, W.; Moreira, T.; Coker, J.; Mukhopadhyay, S.; Williams, E.; Manning, C.; Bohstedt, T.; McCrorie, R.; Fernandez-Cid, A.; Burgess-Brown, N. A.
10.1101/2020.07.24.217562 — biochemistry — Posted on 2020-07-27
889 Accounting for body mass effects in the estimation of field metabolic rates from body acceleration
Byrnes, E.; Lear, K. O.; Brewster, L. R.; Whitney, N. M.; Smukall, M. J.; Armstrong, N. J.; Gleiss, A. C.
10.1101/2020.07.24.219204 — physiology — Posted on 2020-07-27
890 Mutation landscape of SARS-CoV-2 reveals five mutually exclusive clusters of leading and trailing single nucleotide substitutions
Mishra, A.; Pandey, A. K.; Gupta, P.; Pradhan, P.; Dhamija, S.; Gomes, J.; Kundu, B.; Vivekanandan, P.; Menon, M. B.
10.1101/2020.05.07.082768 — genomics — Posted on 2020-07-27
892 Regular Tai Chi Practice Is Associated with Improved Memory as well as Structural and Functional Integrity of the Hippocampal Formation in the Elderly
Yue, C.; Yu, Q.; Zhang, Y.; Herold, F.; Mei, J.; Kong, Z.; Perrey, S.; Liu, J.; Muller, N. G.; Zhang, Z.; Tao, Y.; Kramer, A.; Becker, B.; Zou, L.
10.1101/2020.07.26.222190 — neuroscience — Posted on 2020-07-27
893 Pathogenic mutations in Leucine-rich repeat kinase 2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
Mamais, A.; Landeck, N.; Langston, R. G.; Bonet-Ponce, L.; Smith, N.; Beilina, A.; Kaganovich, A.; Ghosh, M. C.; Pellegrini, L.; Kluss, J. H.; Kumaran, R.; Papazoglou, I.; Maio, N.; Kim, C.; Gershlick, D. C.; Cookson, M. R.
10.1101/2020.07.27.219501 — cell biology — Posted on 2020-07-27
897 Weak catch bonds make strong networks
Mulla, Y.; Avellaneda, M. J.; Roland, A.; Baldauf, L.; Tans, S. J.; Koenderink, G.
10.1101/2020.07.27.219618 — biophysics — Posted on 2020-07-27
900 Host transcriptional responses and SARS-CoV-2 isolates from the nasopharyngeal samples of Bangladeshi COVID-19 patients
Islam, A. B. M. M. K.; Khan, M. A.-A.-K.; Ahmed, R.; Hossain, M. S.; Kabir, S. M. T.; Islam, M. S.; Siddiki, A. M. A. M. Z.
10.1101/2020.07.23.218198 — genomics — Posted on 2020-07-27
902 Inducing Human Retinal Pigment Epithelium-like Cells from Somatic Tissue
Woogeng, I. N.; Abugessaisa, I.; Tachibana, A.; Sahara, Y.; Hon, C.-C.; Hasegawa, A.; Kaczkowski, B.; Sakai, N.; Nishida, M.; Hu, H.; Sanyal, H.; Sho, J.; Kasukawa, T.; Takasato, M.; Carninci, P.; Maeda, A.; Mandai, M.; Arner, E.; Takahashi, M.; Kime, C.
10.1101/2020.07.27.215103 — bioengineering — Posted on 2020-07-27
906 Species detection within the Echinococcus granulosus sensu lato complex by novel probe-based Real-Time PCRs
Maksimov, P.; Bergmann, H.; Wassermann, M.; Romig, T.; Gottstein, B.; Casulli, A.; Conraths, F. J.
10.1101/2020.07.24.220756 — molecular biology — Posted on 2020-07-27
907 Evolution of regulatory signatures in primate cortical neurons at cell type resolution
Kozlenkov, A.; Vermunt, M. W.; Apontes, P.; Li, J.; Hao, K.; Sherwood, C. C.; Hof, P. R.; Ely, J. J.; Wegner, M.; Mukamel, E. A.; Creyghton, M. P.; Koonin, E. V.; Dracheva, S.
10.1101/2020.07.24.219881 — evolutionary biology — Posted on 2020-07-27
908 Temperature Dependence of the Krokinobacter rhodopsin 2 Kinetics
Eberhardt, P.; Slavov, C.; Sörmann, J.; Bamann, C.; Braun, M.; Wachtveitl, J.
10.1101/2020.07.24.219782 — biophysics — Posted on 2020-07-27
909 Distribution of Epsilon-Polylysine Synthetases in Coryneform Bacteria Isolated from Cheese and Human Skin
Jiang, X.; Radko, Y.; Gren, T.; Palazzotto, E.; Jorgensen, T. S.; Cheng, T.; Xian, M.; Weber, T.; Lee, S. Y.
10.1101/2020.07.24.220772 — microbiology — Posted on 2020-07-27
910 Cell-free DNA as a biomarker for prostate cancer: elevated concentration and decreased fragment size
Chen, E.; Cario, C. L.; Leong, L.; Lopez, K.; Marquez, C.; Chu, C.; Li, P. S.; Oropeza, E.; Tenggara, I.; Cowan, J.; Simko, J. P.; Chan, J. M.; Friedlander, T.; Wyatt, A. W.; Aggarwal, R.; Paris, P. L.; Carroll, P. R.; Feng, F.; Witte, J. S.
10.1101/2020.07.26.215020 — cancer biology — Posted on 2020-07-26
917 A high-quality genome assembly and annotation of the gray mangrove, Avicennia marina
Friis, G.; Vizueta, J.; Nelson, D. R.; Khraiwesh, B.; Qudeimat, E.; Salehi-Ashtiani, K.; Ortega, A.; Marshell, A.; Duarte, C. M.; Burt, J. A.
10.1101/2020.05.30.124800 — genomics — Posted on 2020-07-26
918 A simple strategy to reduce the salivary gland and kidney uptake of PSMA targeting small molecule radiopharmaceuticals
Kalidindi, T. M.; Lee, S. G.; Jou, K.; Chakraborty, G.; Skafida, M.; Tagawa, S. T.; Bander, N. H.; Schoder, H.; Bodei, L.; Pandit-Taskar, N.; Lewis, J. S.; Larson, S. M.; Osborne, J. R.; Pillarsetty, N.
10.1101/2020.07.24.220277 — pharmacology and toxicology — Posted on 2020-07-26
920 Evolving Transcriptomic Signature of Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cells With Age
Lidgerwood, G. E.; Senabouth, A.; Smith-Anttila, C. J. A.; Gnanasambandapillai, V.; Kaczorowski, D. C.; Amann-Zalcenstein, D.; Fletcher, E. L.; Naik, S. H.; Hewitt, A. W.; Powell, J.; Pebay, A.
10.1101/842328 — cell biology — Posted on 2020-07-26
922 Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback
Lopacinski, A. B.; Sweatt, A. J.; Smolko, C. M.; Gray-Gaillard, E.; Borgmann, C. A.; Shah, M.; Janes, K. A.
10.1101/2020.07.26.222174 — systems biology — Posted on 2020-07-26
925 Cavin3 released from caveolae interacts with BRCA1to regulate the cellular stress response
Parton, R. G.; McMahon, K.-A.; Stroud, D. A.; Gambin, Y.; Tillu, V.; Bastiani, M.; Sierecki, E.; Polinkovsky, M.; Hall, T. E.; Gomez, G. A.; Wu, Y.; Parat, M.-O.; Martel, N.; Lo, H. P.; Khanna, K. k.; Alexandrov, K.; Daly, R.; Yap, A. S.; Ryan, M.
10.1101/2020.07.26.222158 — cancer biology — Posted on 2020-07-26
926 COVID-19 and Rheumatoid Arthritis share myeloid pathogenic and resolving pathways
MacDonald, L.; Otto, T. D.; Elmesmari, A.; Tolusso, B.; Somma, D.; McSharry, C.; Gremese, E.; McInnes, I. B.; Alivernini, S.; Kurowska-Stolarska, M.
10.1101/2020.07.26.221572 — immunology — Posted on 2020-07-26
927 Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as vaccine candidate
Sun, W.; Leist, S. R.; McCroskery, S.; Liu, Y.; Slamanig, S.; Oliva, J.; Amanat, F.; Schaefer, A.; Dinnon, K.; Garcia-Sastre, A.; Krammer, F.; Baric, R. S.; Palese, P.
10.1101/2020.07.26.221861 — microbiology — Posted on 2020-07-26
928 The SARS-CoV-2 Spike Variant D614G Favors an Open Conformational State
Mansbach, R. A.; Chakraborty, S.; Nguyen, K.; Montefiori, D.; Korber, B.; Gnanakaran, S.
10.1101/2020.07.26.219741 — biophysics — Posted on 2020-07-26
931 Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 - implications for microvascular inflammation and hypercoagulopathy in COVID-19
He, L.; Mae, M. A.; Muhl, L.; Sun, Y.; Pietila, R.; Nahar, K.; Liebanas, E. V.; Fagerlund, M. J.; Oldner, A.; Liu, J.; Genove, G.; Zhang, L.; Xie, Y.; Liptidis, S.; Mocci, G.; Stritt, S.; Osman, A.; Anisimov, A.; Hemanthakumar, K. A.; Rasenen, M.; Mirabeau, O.; Hansson, E.; Bjorkegren, J.; Vanlandewijck, M.; Blomgren, K.; Makinen, T.; Peng, X.-R.; Arnold, T. D.; Alitalo, K.; Eriksson, L. I.; Lendahl, U.; Betsholtz, C.
10.1101/2020.05.11.088500 — pathology — Posted on 2020-07-26
934 A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β-cells
Li, M.; Shao, F.; Qian, Q.; Yu, W.; Zhang, Z.; Chen, B.; Dan, S.; Guo, Y.; Phan, A.-V. D.; Song, L.-S.; Stephens, S. B.; Sebag, J. A.; Imai, Y.; Ling, Y.; Cao, H.
10.1101/2020.05.12.091728 — molecular biology — Posted on 2020-07-26
941 De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release
Elazar, A.; Chandler, N. J.; Davey, A. S.; Weinstein, J. Y.; Nguyen, J. V.; Trenker, R.; Jenkins, M. R.; Call, M. J.; Call, M. E.; Fleishman, S. J.
10.1101/2020.07.26.221598 — synthetic biology — Posted on 2020-07-26
942 An integrated, modular approach to data science education in the life sciences
Dill-McFarland, K. A.; Koenig, S. G.; Mazel, F.; Oliver, D.; McEwen, L. M.; Hong, K. Y.; Hallam, S. J.
10.1101/2020.07.25.218453 — scientific communication and education — Posted on 2020-07-26
944 Quorum Sensing Regulates 'swim-or-stick' Lifestyle in the Phycosphere
Fei, C.; Ochsenkuhn, M. A.; Shibl, A. A.; Isaac, A.; Wang, C.; Amin, S. A.
10.1101/2020.07.26.221937 — ecology — Posted on 2020-07-26
945 Cytokinetic abscission is part of the mid-blastula transition switch in early zebrafish embryogenesis
Adar-Levor, S.; Nachmias, D.; Gal-Oz, S. T.; Jahn, Y. M.; Peyrieras, N.; Zaritsky, A.; Birnbaum, R. Y.; Elia, N.
10.1101/2020.07.26.221515 — developmental biology — Posted on 2020-07-26
949 Effects Of Microplastics And Drought On Ecosystem Functions And Multifunctionality
Lozano, Y. M.; Aguilar-Trigueros, C. A.; Onandia, G.; Maass, S.; Zhao, T.; Rillig, M. C.
10.1101/2020.07.26.221929 — ecology — Posted on 2020-07-26
950 We think what we eat: Animal-based diet influences cerebral and microbiota networks connectivity in early ages. A study case of an indigenous community in Mexico.
Ramirez-Carrillo, E.; Gonzalez-Santoyo, I.; Lopez-Corona, O.; Rojas-Ramos, O. A.; Falcon, L. I.; Gaona, O.; Cerqueda-Garcia, D.; Sanchez-Quinto, A.; de la Fuente Rodriguez, R. M.; Hernandez Castillo, A.; Nieto, J.
10.1101/2020.07.25.221408 — neuroscience — Posted on 2020-07-26
951 Regulated distribution of mitochondria in touch receptor neurons of C. elegans influences touch response
Awasthi, A.; Modi, S.; Hegde, S.; Chatterjee, A.; Mondal, S.; Romero, E.; Sure, G. R.; Koushika, S. P.
10.1101/2020.07.26.221523 — neuroscience — Posted on 2020-07-26
958 Waking experience modulates sleep need in mice
Milinski, L.; Fisher, S. P.; Cui, N.; McKillop, L. E.; Blanco Duque, C.; Ang, G.; Yamagata, T.; Bannerman, D. M.; Vyazovskiy, V. V.
10.1101/2020.07.25.219642 — neuroscience — Posted on 2020-07-26
959 Distinct microbial communities along the chronic oil pollution continuum of the Persian Gulf converge with oil spill accidents
Rezaei Somee, M.; Dastgheib, S. M. M.; Shavandi, M.; Ghanbari Maman, L.; Kavousi, K.; Amoozegar, M. A.; Mehrshad, M.
10.1101/2020.07.25.221044 — microbiology — Posted on 2020-07-26
960 The impact of microclimate and soil on the ecology and evolution of an arctic plant
Wickander, N. J.; Rasmussen, P. U.; Marteinsdottir, B.; Ehrlen, J.; Tack, A. J. M.
10.1101/2020.07.26.221721 — ecology — Posted on 2020-07-26
961 Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction
Rhee, S.; Paik, D. T.; Yang, J. Y.; Nagelberg, D.; Williams, I. M.; Tian, L.; Roth, R.; Chandy, M.; Ban, J.; Belbachir, N.; Kim, S.; Zhang, H.; Phansalkar, R.; Wong, K. M.; King, D. A.; Valdez, C.; Winn, V. D.; Morrison, A. J.; Wu, J. C.; Red-Horse, K.
10.1101/2020.07.25.220301 — developmental biology — Posted on 2020-07-26
962 Megadalton-sized dityrosine aggregates of α-synuclein retain high degrees of structural disorder and internal dynamics.
Verzini, S.; Shah, M.; Theillet, F.-X.; Belsom, A.; Bieschke, J.; Wanker, E. E.; Rappsilber, J.; Binolfi, A.; Selenko, P.
10.1101/2020.07.26.202358 — biophysics — Posted on 2020-07-26
964 Evaluation of near infrared spectroscopy for sporozoite detection in mosquitoes infected with wild-strain parasites from asymptomatic gametocyte carriers in Kilifi Kenya
Ferreira Maia, M.; Wagah, M. G.; Karisa, J.; Mwakesi, R.; Mure, F.; Muturi, M.; Wambua, J.; Hamaluba, M.; Dowell, F.; Bejon, P.; Kapulu, M.
10.1101/2020.07.25.220830 — zoology — Posted on 2020-07-26
965 Role for novel family of pathogen-induced cysteine-rich transmembrane proteins in disease resistance
Pereira Mendes, M.; Hickman, R.; Van Verk, M. C.; Nieuwendijk, N.; Reinstadler, A.; Panstruga, R.; Pieterse, C. M. J.; Van Wees, S. C. M.
10.1101/2020.07.25.220970 — plant biology — Posted on 2020-07-26
967 Full genome characterization of Laem Singh virus (LSNV) in shrimp Penaeus monodon
Taengchaiyaphum, S.; Srisala, J.; Sanguanrut, P.; Ongvarrasopone, C.; Flegel, T. W.; Sritunyalucksana, K.
10.1101/2020.07.25.221432 — microbiology — Posted on 2020-07-26
968 A unified atlas of CD8 T cell dysfunctional states in cancer and infection
Pritykin, Y.; van der Veeken, J.; Pine, A.; Zhong, Y.; Sahin, M.; Mazutis, L.; Pe'er, D.; Rudensky, A.; Leslie, C. S.
10.1101/2020.07.25.220673 — genomics — Posted on 2020-07-26
972 The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in an in vitro ALS Model
Sannigrahi, A.; Chowdhury, S.; Das, B.; Banerjee, A.; Halder, A.; Naganathan, A. N.; Karmakar, S.; Chattopadhyay, K.
10.1101/2020.07.25.220962 — biophysics — Posted on 2020-07-26
974 Transposable Element-Gene Splicing Modulates the Transcriptional Landscape of Human Pluripotent Stem Cells
Babarinde, I. A.; Ma, G.; Li, Y.; Deng, B.; Luo, Z.; Liu, H.; Abdul, M.; Ward, C.; Chen, M.; Fu, X.; Duttlinger, M.; He, J.; Sun, L.; Li, W.; Zhuang, Q.; Frampton, J.; Cazier, J.-B.; Chen, J.; Jauch, R.; Esteban, M. A.; Hutchins, A.
10.1101/2020.07.26.220608 — genomics — Posted on 2020-07-26
978 Pharmacological prevention of neonatal opioid withdrawal in a pregnant guinea pig model.
Safa, A.; Lau, A. R.; Aten, S.; Schilling, K.; Bales, K. L.; Miller, V. A.; Fitzgerald, J.; Chen, M.; Hill, K.; Dzwigalski, K.; Obrietan, K.; Phelps, M. A.; Sadee, W.; Oberdick, J.
10.1101/2020.07.25.221192 — pharmacology and toxicology — Posted on 2020-07-26
982 Identifying hidden drivers of heterogeneous inflammatory diseases
Garzorz-Stark, N.; Batra, R.; Lauffer, F.; Jargosch, M.; Pilz, C.; Roenneberg, S.; Schaebitz, A.; Boehner, A.; Seiringer, P.; Thomas, J.; Fereydouni, B.; Tsoi, L. C.; Gudjonsson, J. E.; Theis, F. F.; Biedermann, T.; Schmidt-Weber, C. B.; Mueller, N.; Eyerich, S.; Eyerich, K.
10.1101/2020.07.25.221309 — immunology — Posted on 2020-07-26
985 A mitochondrial mutational signature of temperature and longevity in ectothermic and endothermic vertebrates.
Mikhailova, A. G.; Shamanskiy, V.; Mihailova, A. A.; Ushakova, K.; Tretiakov, E.; Oreshkov, S.; Knorre, D.; Polishchuk, L.; Lawless, D.; Mazunin, I.; Kunz, W.; Tanaka, M.; Fleischmann, Z.; Aidlen, D.; Makeev, V.; Kuptsov, A.; Fellay, J. S.; Khrapko, K.; Gunbin, K.; Popadin, K.
10.1101/2020.07.25.221184 — evolutionary biology — Posted on 2020-07-26
989 Arabidopsis thaliana interaction with Ensifer meliloti can support plant growth under N-deficiency
Armijo, G.; Kraiser, T.; Medina, M. P.; Gras, D. E.; Zuniga, A.; Gonzalez, B.; Gutierrez, R. A.
10.1101/2020.07.25.221283 — plant biology — Posted on 2020-07-26
1004 The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research
Vandenabeele, M.; Veys, L.; Lemmens, S.; Hadoux, X.; Gelders, G.; Masin, L.; Serneels, L.; Theunis, J.; Saito, T.; Saido, T.; Jayapala, M.; De Boever, P.; De Strooper, B.; Stalmans, I.; van Wijngaarden, P.; Moons, L.; De Groef, L.
10.1101/2020.07.25.220707 — neuroscience — Posted on 2020-07-26
1007 Modeling Alpha-Synuclein Pathology in a Human Brain-Chip to Assess Blood-Brain Barrier Disruption in Parkinson's Disease
Pediaditakis, I.; Kodella, K. R.; Manatakis, D. V.; Hinojosa, C. D.; Manolakos, E. S.; Rubin, L. L.; Hamilton, G. A.; Karalis, K.
10.1101/2020.07.22.207340 — bioengineering — Posted on 2020-07-26
1010 Transcriptomic Response of Brain Tissue to Focused Ultrasound-Mediated Blood-Brain Barrier Disruption Depends Strongly on Anesthesia
Mathew, A. S.; Gorick, C. M.; Thim, E. A.; Garrison, W. J.; Klibanov, A. L.; Miller, G. W.; Sheybani, N. D.; Price, R. J.
10.1101/2020.07.24.211136 — bioengineering — Posted on 2020-07-26
1020 Inducing highly physiologically relevant phenotypes of human vascular smooth muscle cells via 3D printing
Zhu, P.; Li, X.; Xin, W.; Wang, M.; Yin, C.; Li, J.; Chen, H.; Zhu, H.; Sun, Y.; Jia, J.; Zhou, N.
10.1101/2020.07.24.206888 — bioengineering — Posted on 2020-07-26
1022 A simple strategy to reduce the salivary gland and kidney uptake of PSMA targeting small molecule radiopharmaceuticals
PILLARSETTY, N.; Kalidindi, T. M.; Lee, S. G.; Jou, K.; Chakraborty, G.; Skafida, M.; Tagawa, S. T.; Bander, N. H.; Schoder, H.; Bodei, L.; Pandit-Taskar, N.; Lewis, J. S.; Larson, S. M.; Osborne, J. R.
10.1101/2020.07.24.220277 — pharmacology and toxicology — Posted on 2020-07-26
1028 Validating layer-specific VASO across species
Huber, L.; Poser, B.; Kaas, A. L.; Fear, E. J.; Dresbach, S.; Berwick, J.; Goebel, R. W.; Turner, R.; Kennerley, A. J.
10.1101/2020.07.24.219378 — neuroscience — Posted on 2020-07-26
1029 Effects of individual base-pairs on in vivo target search and destruction kinetics of small RNA
Poddar, A.; Azam, M. S.; Kayikcioglu, T.; Bobrovskyy, M.; Zhang, J.; Ma, X.; Labhsetwar, P.; Fei, J.; Singh, D.; Luthey-Schulten, Z.; Vanderpool, C. K.; Ha, T.
10.1101/2020.07.24.215095 — molecular biology — Posted on 2020-07-26
1030 Inference of a genome-wide protein-coding gene set of the inshore hagfish Eptatretus burgeri
Yamaguchi, K.; Hara, Y.; Kaori, T.; Nishimura, O.; Smith, J.; Kadota, M.; Kuraku, S.
10.1101/2020.07.24.218818 — genomics — Posted on 2020-07-26
1032 Computer vision approach to characterize size and shape phenotypes of horticultural crops using high-throughput imagery
Haque, S.; Lobaton, E.; Nelson, N.; Yencho, G. C.; Pecota, K. V.; Mierop, R.; Kudenov, M. W.; Boyette, M.; Williams, C. M.
10.1101/2020.07.24.199539 — bioengineering — Posted on 2020-07-26
1035 The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocytes and lung epithelial cells and decrease the production of proinflammatory cytokines in infected cells.
Temerozo, J. R.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Pao, C. R. R.; de Freitas, C. S.; Dias, S. d. S. G.; Ferreira, A. C.; Mattos, M.; Soares, V. C.; Teixeira, L.; de Azevedo-Quintanilha, I. G.; Kurtz, P.; Bozza, F. A.; Bozza, P. T.; Souza, T. M. L.; Bou-Habib, D. C.
10.1101/2020.07.25.220806 — microbiology — Posted on 2020-07-26
1036 North American deer mice are susceptible to SARS-CoV-2
Griffin, B. D.; Chan, M.; Tailor, N.; Mendoza, E. J.; Leung, A.; Warner, B. M.; Duggan, A. T.; Moffat, E.; He, S.; Garnett, L.; Tran, K. N.; Banadyga, L.; Albietz, A.; Tierney, K.; Audet, J.; Bello, A.; Vendramelli, R.; Boese, A. S.; Fernando, L.; Lindsay, L. R.; Jardine, C. M.; Wood, H.; Poliquin, G.; Strong, J. E.; Drebot, M.; Safronetz, D.; Embury-Hyatt, C.; Kobasa, D.
10.1101/2020.07.25.221291 — microbiology — Posted on 2020-07-26
1037 CoVaccine HT™ adjuvant potentiates robust immune responses to recombinant SARS-CoV-2 Spike S1 immunisation
Haun, B. K.; Lai, C.-Y.; Williams, C. A.; Wong, T. A. S.; Lieberman, M. M.; Pessaint, L.; Elyard, H. A.; Lehrer, A. T.
10.1101/2020.07.24.220715 — immunology — Posted on 2020-07-26
1038 Brain geometry matters in Alzheimer disease progression: a simulation study
Hoore, M.; Kelling, J.; Sayadmanesh, M.; Mitra, T.; Schips, M.; Meyer-Hermann, M.
10.1101/2020.07.24.220228 — systems biology — Posted on 2020-07-25
1041 The lysosomal V-ATPase B1 subunit in proximal tubule is linked to nephropathic cystinosis
Jamalpoor, A.; van Eerde, A.; Lilien, M. R.; van Gelder, C. A.; Zaal, E. A.; Valentijn, F. A.; Broekhuizen, R.; zielhuis, E.; Egido, J. E.; Altelaar, M.; Berkers, C. R.; Masereeuw, R.; Janssen, M. J.
10.1101/2020.07.24.219808 — pharmacology and toxicology — Posted on 2020-07-25
1044 High neutralizing potency of swine glyco-humanized polyclonal antibodies against SARS-CoV-2
Vanhove, B.; Duvaux, O.; Rousse, J.; Royer, P.-J.; Evanno, G.; Ciron, C.; Lheriteau, E.; Vacher, L.; Gervois, N.; Oger, R.; Jacques, Y.; Salama, A.; Duchi, R.; Perota, A.; Delahaut, P.; Ledure, M.; Paulus, M.; So, R.; Mok, C. K. P.; Bruzzone, R.; Bouillet, M.; Brouard, S.; Cozzi, E.; Galli, C.; Blanchard, D.; Bach, J.-M.; Soulillou, J.-P.
10.1101/2020.07.25.217158 — immunology — Posted on 2020-07-25
1046 β-Coronaviruses use lysosomal organelles for cellular egress.
Altan-Bonnet, N.; Altan-Bonnet, G. Y.; Ghosh, S.; Dellibovi-Ragheb, T.; Pak, E.; Qiu, Q.; Fisher, M.; Takvorian, P.; Bleck, C.; Hsu, V.; Fehr, A.; Perlman, S.; Straus, M.; Whittaker, G.; de Haan, C. A.
10.1101/2020.07.25.192310 — microbiology — Posted on 2020-07-25
1049 Quantitative Proteomics and Phosphoproteomics Supports a Role for Mut9-Like Kinases in Multiple Metabolic and Signaling Pathways in Arabidopsis
Wilson, M. E.; Tzeng, S.-C.; Augustin, M. M.; Meyer, M.; Jiang, X.; Choi, J. H.; Rogers, J. C.; Evans, B. S.; Kutchan, T. M.; Nusinow, D. A.
10.1101/2020.02.14.950030 — plant biology — Posted on 2020-07-25
1050 The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle
Furlan-Magaril, M.; Ando-Kuri, M.; Arzate-Mejia, R. G.; Morf, J.; Cairns, J.; Poot- Hernandez, C. A.; Andrews, S.; Varnai, C.; Virk, B.; Wingett, S. W.; Fraser, P.
10.1101/2020.07.23.217992 — genomics — Posted on 2020-07-25
1053 Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling
Amar, M.; Pramod, A. B.; Yu, N.-K.; Herrera, V. M.; Qiu, L. R.; Moran-Losada, P.; Zhang, P.; Trujillo, C. A.; Ellegood, J.; Urresti, J.; Chau, K.; Diedrich, J.; Chen, J.; Gutierrez, J.; Sebat, J.; Ramanathan, D.; Lerch, J. P.; Yates, J. R.; Muotri, A. R.; Iakoucheva, L. M.
10.1101/2020.02.07.939256 — neuroscience — Posted on 2020-07-25
1055 Top-down engineering of complex communities by directed evolution
Chang, C.-Y.; Vila, J. C. C.; Bender, M.; Li, R.; Mankowski, M. C.; Bassette, M.; Borden, J.; Golfier, S.; Sanchez, P. G.; Waymack, R.; Zhu, X.; Diaz-Colunga, J.; Estrela, S.; Rebolleda-Gomez, M.; Sanchez, A.
10.1101/2020.07.24.214775 — evolutionary biology — Posted on 2020-07-25
1056 Lineage specific transcription factor waves reprogram neuroblastoma from self-renewal to differentiation
Banerjee, D.; Gryder, B.; Bagchi, S.; Liu, Z.; Chen, H.-C.; Xu, M.; Sun, M.; Vaksman, Z.; Diskin, S. J.; Khan, J.; Thiele, C.
10.1101/2020.07.23.218503 — cancer biology — Posted on 2020-07-25
1058 Freshwater monitoring by nanopore sequencing
Urban, L.; Holzer, A.; Baronas, J. J.; Hall, M.; Braeuninger-Weimer, P.; Scherm, M. J.; Kunz, D. J.; Perera, S. N.; Martin-Herranz, D. E.; Tipper, E. T.; Salter, S. J.; Stammnitz, M. R.
10.1101/2020.02.06.936302 — microbiology — Posted on 2020-07-25
1062 Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability
Kulik, A. A.; Maruszczak, K. K.; Thomas, D. C.; Nabi, N. L. A.; Carr, M.; Bingham, R. J.; Cooper, C. D. O.
10.1101/2020.07.24.219980 — biochemistry — Posted on 2020-07-25
1063 The developmental and genetic architecture of the sexually selected male ornament of swordtails
Schartl, M.; Kneitz, S.; Ormanns, J.; Schmidt, C.; Anderson, J. L.; Amores, A.; Catchen, J. M.; Wilson, C.; Geiger, D.; Du, K.; Garcia-Olazabal, M.; Sudaram, S.; Winkler, C.; Hedrich, R.; Warren, W. C.; Walter, R.; Meyer, A.; Postlethwait, J. H.
10.1101/2020.07.24.219840 — evolutionary biology — Posted on 2020-07-25
1065 In Silico Analysis of Secondary Metabolites that Modulates Enzymes of Cholesterol Target
Marahatha, R.; Basnet, S.; Bhattarai, B. R.; Budhathoki, P.; Aryal, B.; Adhikari, B.; Lamichhane, G.; Poudel, D. K.; Parajuli, N.
10.1101/2020.07.24.219998 — biochemistry — Posted on 2020-07-25
1066 Neuroanatomical dissociations of syntax and semantics revealed by lesion-symptom mapping
Matchin, W.; Basilakos, A.; den Ouden, D.-B.; Stark, B.; Hickok, G.; Fridriksson, J.
10.1101/2020.07.17.209262 — neuroscience — Posted on 2020-07-25
1070 Severe perinatal hydrops fetalis in genome edited pigs with a biallelic five base pair deletion of the Marfan syndrome gene, FBN1
Tsang, H.-G.; Lillico, S.; Proudfoot, C.; McCulloch, M. E. B.; Markby, G. R.; Trejo-Reveles, V.; Corcoran, B. M.; Whitelaw, C. B. A.; MacRae, V. E.; Summers, K. M.
10.1101/2020.07.20.213108 — molecular biology — Posted on 2020-07-25
1072 Sister chromatid repair maintains genomic integrity during meiosis in Caenorhabditis elegans
Toraason, E.; Clark, C.; Horacek, A.; Glover, M. L.; Salagean, A.; Libuda, D. E.
10.1101/2020.07.22.216143 — genetics — Posted on 2020-07-25
1073 The bakerss yeast Msh4-Msh5 associates with double-strand break hotspots and chromosome axis during meiosis to promote crossovers
Nandanan, K. G.; Pankajam, A. V.; Salim, S.; Shinohara, M.; Lin, G.; Chakraborty, P.; Steinmetz, L. M.; Shinohara, A.; Nishant, K. T.
10.1101/2020.07.24.219295 — genetics — Posted on 2020-07-25
1074 Balancing selection maintains ancient genetic diversity in C. elegans
Lee, D.; Zdraljevic, S.; Stevens, L.; Wang, Y.; Tanny, R. E.; Crombie, T. A.; Cook, D. E.; Webster, A. K.; Chirakar, R.; Baugh, L. R.; Sterken, M.; Braendle, C.; Felix, M.-A.; Rockman, M.; Andersen, E. C.
10.1101/2020.07.23.218420 — evolutionary biology — Posted on 2020-07-25
1077 Private information leakage from functional genomics data: Quantification with calibration experiments and reduction via data sanitization protocols
Gursoy, G.; Emani, P. S.; Brannon, C.; Jolanki, O. A.; Harmanci, A. O.; Strattan, J. S.; Miranker, A. D.; Gerstein, M.
10.1101/345074 — bioinformatics — Posted on 2020-07-25
1078 G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT
Alghamri, M. S.; Avvari, R.; Thalla, R.; Kamran, N.; Zhang, L.; Ventosa, M.; Taher, A.; Faisal, S.; Nunez, F.; Garcia-Fabiani, M.; Haase, S.; Carney, S.; Orringer, D.; Hervey-Jumper, S.; Heth, J.; Patil, P. G.; Al-Holou, W.; Merajver, S.; Ulintz, P.; Welch, J.; Gao, C.; Liu, J.; Eddy, K.; Nunez, G.; Hambardzumyan, D.; Lowenstein, P.; Castro, M. G.
10.1101/2020.07.22.215954 — cancer biology — Posted on 2020-07-25
1079 Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to High Fructose Consumption in Mice
Ahn, I. S.; Lang, J. M.; Olson, C.; Diamante, G.; Zhang, G.; Ying, Z.; Byun, H. R.; Cely, I.; Ding, J.; Cohn, P.; Kurtz, I.; Gomez-Pinilla, F.; Lusis, A. J.; Hsiao, E.; Yang, X.
10.1101/439786 — systems biology — Posted on 2020-07-25
1080 A nutrient-responsive hormonal circuit controls energy and water homeostasis in Drosophila
Koyama, T.; Terhzaz, S.; Naseem, M. T.; Nagy, S.; Rewitz, K.; Dow, J. A. T.; Davies, S. A.; Halberg, K. A.
10.1101/2020.07.24.219592 — physiology — Posted on 2020-07-25
1082 Neuropsychiatric mutations delineate functional brain connectivity dimensions contributing to autism and schizophrenia
Moreau, C. A.; Urchs, S.; Kuldeep, K.; Orban, P.; Schramm, C.; Dumas, G.; Labbe, A.; Huguet, G.; Douard, E.; Quirion, P.-O.; Lin, A.; Kushan, L.; Grot, S.; Luck, D.; Mendrek, A.; Potvin, S.; Stip, E.; Bourgeron, T.; Evans, A. C.; SimonsVIP Consortium, ; Bearden, C. E.; Bellec, P.; Jacquemont, S.
10.1101/862615 — neuroscience — Posted on 2020-07-25
1083 Mtg16-dependent repression of E protein activity is required for early lymphopoiesis
Acharya, P.; Sampathi, S.; Flaherty, D. K.; Matlock, B. K.; Williams, C. S.; Hiebert, S. W.; Stengel, K. R.
10.1101/2020.07.24.220525 — genetics — Posted on 2020-07-25
1086 In Silico Analysis of Secondary Metabolites that Modulates Enzymes of Cholesterol Target
Marahatha, R.; Basnet, S.; Bhattarai, B. R.; Budhathoki, P.; Aryal, B.; Adhikari, B.; Lamichhane, G.; Poudel, D. K.; Parajuli, N.
10.1101/2020.07.24.219998 — biochemistry — Posted on 2020-07-25
1087 Prokaryotic rRNA-mRNA interactions are involved in all translation steps and shape bacterial transcripts
Bahiri Elitzur, S.; Cohen-Kupiec, R.; Yacobi, D.; Fine, L.; Apt, B.; Diament, A.; Tuller, T.
10.1101/2020.07.24.220731 — systems biology — Posted on 2020-07-25
1088 Synapsin-caveolin-1 mitigates cognitive deficits and neurodegeneration in Alzheimer's disease mice
Wang, S.; Leem, J.; Podvin, S.; Hook, V.; Kleschevnikov, N.; Savchenko, P.; Dhanani, M.; Zhou, K.; Kelly, I.; Zhang, T.; Miyanohara, A.; Kleschevnikov, A.; Wagner, S.; Trojanowski, J.; Roth, D.; Patel, H.; Patel, P.; Head, B. P.
10.1101/2020.07.24.220129 — neuroscience — Posted on 2020-07-25
1089 TRANsCre-DIONE transdifferentiates scar-forming reactive astrocytes into functional motor neurons
An, H.; Lee, H.-L.; Cho, D.-W.; Hong, J.; Lee, H. Y.; Lee, J. M.; Woo, J.; Lee, J.; Park, M.; Yang, Y.-S.; Han, S.-C.; Ha, Y.; Lee, C. J.
10.1101/2020.07.24.215160 — neuroscience — Posted on 2020-07-25
1090 The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer
Morgan, E. L.; Patterson, M. R.; Barba-Moreno, D.; Wilson, A.; Macdonald, A.
10.1101/2020.07.25.220996 — microbiology — Posted on 2020-07-25
1091 AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans
Sayed, F. A.; Kodama, L.; Udeochu, J. C.; Fan, L.; Carling, G. K.; Le, D.; Li, Q.; Zhou, L.; Mathys, H.; Wang, M.; Niu, X.; Mazutis, L.; Jiang, X.; Wang, X.; Wong, M. Y.; Gao, F.; Telpoukhovskaia, M.; Tracy, T. E.; Frost, G.; Zhou, Y.; Li, Y.; Brendel, M.; Qiu, Y.; Cheng, Z.; Yu, G.; Hardy, J.; Coppola, G.; Gong, S.; Wang, F.; DeTure, M. A.; Zhang, B.; Xie, L.; Dickson, D. W.; Luo, W.; Gan, L.
10.1101/2020.07.24.218719 — neuroscience — Posted on 2020-07-25
1093 NT3/TrkC pathway modulates the expression of UCP-1 and adipocyte size in human and murine adipose tissue
Bove, M.; Monto, f.; Guillen-Llobat, P.; Ivorra, M. D.; Noguera, M.; Zambrano, A.; Sirerol-Piquer, S.; Requena, A. C.; Garcia-Alonso, M.; Tejerina, T.; Real, J. T.; Farinas, I.; D'Ocon, P.
10.1101/2020.07.24.216374 — physiology — Posted on 2020-07-25
1094 Branched-Chain Amino Acid Metabolism is Regulated by ERRα and is Further Impaired by Glucose Loading in Type 2 Diabetes
Sjögren, R. J. O.; Rizo-Roca, D.; Chibalin, A. V.; Chorell, E.; Furrer, R.; Katayama, S.; Harada, J.; Karlsson, H. K. R.; Handschin, C.; Moritz, T.; Krook, A.; Näslund, E.; Zierath, J. R.
10.1101/2020.07.24.218099 — physiology — Posted on 2020-07-25
1095 Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast
Garrido-Godino, A. I.; Gupta, I.; Gutierrez-Santiago, F.; Martinez-Padilla, A. B.; Alekseenko, A.; Steinmetz, L. M.; Perez-Ortin, J. E.; Pelechano, V.; Navarro, F.
10.1101/2020.07.25.220095 — molecular biology — Posted on 2020-07-25
1096 AKT-like kinase promotes cell survival during nutritional stress in tripanosomatids
Diez-Mejia, A. F.; Pedroza, M. M.; Orrego, L. M.; Pulido, S. A.; Echeverry, M. C.; Rojas, M.; Soares, M. J.; Muskus, C. E.; Robledo, S. M.; Marin-Villa, M.; Varela-Miranda, R. E.
10.1101/2020.07.25.218644 — microbiology — Posted on 2020-07-25
1097 Benchmarking challenging small variants with linked and long reads
Wagner, J.; Olson, N. D.; Harris, L.; Khan, Z.; Farek, J.; Mahmoud, M.; Stankovic, A.; Kovacevic, V.; Wenger, A. M.; Rowell, W. J.; Xiao, C.; Yoo, B.; Miller, N.; Rosenfeld, J. A.; Ni, B.; Zarate, S.; Kirsche, M.; Aganezov, S.; Schatz, M.; Narzisi, G.; Byrska-Bishop, M.; Clarke, W.; Evani, U. S.; Markello, C.; Shafin, K.; Zhou, X.; Sidow, A.; Bansal, V.; Martinez Barrio, A.; Fiddes, I. T.; Fungtammasan, A.; Chin, C.-S.; Sedlazeck, F. J.; Carroll, A.; Salit, M.; Zook, J. M.; Genome in a Bottle Consortium,
10.1101/2020.07.24.212712 — genomics — Posted on 2020-07-25
1103 Screening of Botanical Drugs Against Lassa Virus Entry
Liu, Y.; Guo, J.; Cao, J.; Zhang, G.; Jia, X.; Wang, P.; Xiao, G.; Wang, W.
10.1101/2020.07.24.220749 — microbiology — Posted on 2020-07-25
1106 Myeloid lncRNA LOUP Mediates Opposing Regulatory Effects of RUNX1 and RUNX1-ETO in t(8;21) AML
Trinh, B. Q.; Ummarino, S.; Ebralidze, A. K.; van der Kouwe, E.; Bassal, M. A.; Nguyen, T. M.; Coffey, R.; Tenen, D. E.; Fabiani, E.; Gurnari, C.; Wu, C.-S.; Angarica, V. E.; Zhang, Y.; Ying, L.; Yang, H.; Heller, G.; Chen, S.; Zhang, H.; Thurm, A. R.; Marchi, F.; Levantini, E.; Staber, P. B.; Zhang, P.; Voso, M. T.; Pandolfi, P. P.; Di Ruscio, A.; Tenen, D. G.
10.1101/2020.07.24.220020 — cancer biology — Posted on 2020-07-25
1107 Hyper-Truncated N-Acetyl-β-D-Glucosamine Decorations Augment the Activity and Inhibition Potential of Neutrophil Granule Myeloperoxidase
Tjondro, H. C.; Ugonotti, J.; Kawahara, R.; Chatterjee, S.; Loke, I.; Chen, S.; Soltermann, F.; Hinneburg, H.; Parker, B. L.; Venkatakrishnan, V.; Dieckmann, R.; Grant, O. C.; Bylund, J.; Rodger, A.; Woods, R. J.; Struwe, W. B.; Karlsson-Bengtsson, A.; Thaysen-Andersen, M.
10.1101/2020.07.24.219956 — biochemistry — Posted on 2020-07-25
1110 Genes influencing phage host range in Staphylococcus aureus on a species-wide scale
Moller, A. G.; Hargita Davis, M. N.; Winston, K.; Ji, S.; Wang, J.; Solis-Lemus, C. R.; Read, T.
10.1101/2020.07.24.218685 — microbiology — Posted on 2020-07-25
1112 The Harmine and Exendin-4 Combination Markedly Expands Human Beta Cell Mass In Vivo: Quantification and Visualization By iDISCO+ 3D Imaging
Rosselot, C.; Alvarsson, A.; Wang, P.; Li, Y.; Kumar, K.; DeVita, R. J.; Stewart, A. F.; Stanley, S. A.; Garcia-Ocana, A.
10.1101/2020.07.24.220244 — cell biology — Posted on 2020-07-25
1113 Kinetochore individualization in meiosis I is required for centromeric cohesin removal in meiosis II
Gryaznova, Y.; Keating, L.; Touati, S. A.; Cladiere, D.; El Yakoubi, W.; Buffin, E.; Wassmann, K.
10.1101/2020.07.24.219873 — cell biology — Posted on 2020-07-25
1116 Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology
Hansen, F. M.; Tanzer, M. C.; Bruening, F.; Bludau, I.; Schulman, B. A.; Robles, M. S.; Karayel, O.; Mann, M.
10.1101/2020.07.24.219055 — systems biology — Posted on 2020-07-25
1118 Ezh2 restrains macrophage inflammatory responses, and is critical for neutrophil migration in response to pulmonary infection.
Kitchen, G. B.; Hopwood, T.; Ramamoorthy, T. G.; Downton, P.; Begley, N.; Hussell, T.; Dockrell, D. H.; Gibbs, J. E.; Ray, D. W.; Loudon, A. S.
10.1101/2020.07.24.219154 — cell biology — Posted on 2020-07-25
1120 Hijacking of the host cell Golgi by Plasmodium liver stage parasites
de Niz, M.; Kaiser, G.; Zuber, B.; Heo, W. D.; Heussler, V. T.; Agop Nersesian, C.
10.1101/2020.07.24.220137 — cell biology — Posted on 2020-07-25
1122 A Humanized Antibody against LRG1 that Inhibits Angiogenesis and Reduces Retinal Vascular Leakage
Kallenberg, D.; Tripathi, V.; Javaid, F.; Pilotti, C.; George, J.; Davis, S.; Blackburn, J. W.; O'Connor, M.; Dowsett, L.; Bowers, C.; Liyanage, S. E.; Gourlaouen, M.; Hoeh, A.; Mota, F.; Selwood, D.; Bainbridge, J.; Chudasama, V.; Greenwood, J.; Moss, S. E.
10.1101/2020.07.25.218149 — pathology — Posted on 2020-07-25
1123 Huntingtin lowering reduces somatic instability at CAG-expanded loci
Coffey, S. R.; Andrew, M.; Ging, H.; Hamilton, J.; Flower, M.; Kovalenko, M.; Bragg, R. M.; Cantle, J. P.; McHugh, C. A.; Carrillo, J. M.; Rodier, J.-A.; Marchionini, D. M.; Wilkinson, H. A.; Kwak, S.; Howland, D. S.; Bennett, C. F.; Mouro Pinto, R.; Auburger, G.; Zeitlin, S. O.; Kordasiewicz, H. B.; Tabrizi, S. J.; Wheeler, V. C.; Carroll, J. B.
10.1101/2020.07.23.218347 — neuroscience — Posted on 2020-07-25
1124 Calcium binding protein Ncs1 is calcineurin-regulated in Cryptococcus neoformans and essential for cell division and virulence
Squizani, E. D.; Reuwsaat, J. C. V.; Lev, S.; Motta, H.; Sperotto, J.; Kaufman-Francis, K.; Desmarini, D.; Vainstein, M. H.; Staats, C. C.; Djordjevic, J. T.; Kmetzsch, L.
10.1101/2020.07.23.218974 — microbiology — Posted on 2020-07-25
1125 Four-dimensional characterization of the Babesia divergens asexual life cycle: from the trophozoite to the multiparasite stage
Conesa, J. J.; Sevilla, E.; Terron, M. C.; Gonzalez, L. M.; Gray, J.; Perez-Berna, A. J.; Carrascosa, J. L.; Pereiro, E.; Chichon, J.; Luque, D.; Montero, E.
10.1101/2020.07.23.219030 — microbiology — Posted on 2020-07-25
1126 No endospore formation confirmed in members of the phylum Proteobacteria
Beskrovnaya, P.; Fakih, D.; Sexton, D. L.; Xing, S.; Golmohammadzadeh, M.; Morneau, I.; Guadarrama Bello, D.; Nanci, A.; Huan, T.; Tocheva, E.
10.1101/2020.07.23.219022 — microbiology — Posted on 2020-07-25
1127 Spotting genome-wide pigmentation variation in a brown trout admixture context
VALETTE, T.; LEITWEIN, M.; LASCAUX, J.-M.; DESMARAIS, E.; BERREBI, P.; GUINAND, B.
10.1101/2020.07.23.217109 — evolutionary biology — Posted on 2020-07-25
1129 Biophysical and dynamic characterization of a fine-tuned binding of the human Respiratory Syncytial Virus M2-1 core domain to long RNAs
Caruso, I. P.; Guimaraes, G. C.; Machado, V. B.; Fossey, M. A.; Willbold, D.; Almeida, F. C. L.; Souza, F. P.
10.1101/2020.07.22.216952 — biophysics — Posted on 2020-07-25
1131 Genome-wide Spatial Expression Profiling in FFPE Tissues
Gracia Villacampa, E.; Larsson, L.; Kvastad, L.; Andersson, A.; Carlson, J.; Lundeberg, J.
10.1101/2020.07.24.219758 — genetics — Posted on 2020-07-25
1136 Structure of human sodium leak channel NALCN in complex with FAM155A
Xie, J.; Ke, M.; Xu, L.; Lin, S.; Zhang, J.; Yang, F.; Wu, J.; Yan, Z.
10.1101/2020.07.24.218958 — biophysics — Posted on 2020-07-25
1138 What the Phage: A scalable workflow for the identification and analysis of phage sequences
Marquet, M.; Hölzer, M.; Pletz, M. W.; Viehweger, A.; Makarewicz, O.; Ehricht, R.; Brandt, C.
10.1101/2020.07.24.219899 — bioinformatics — Posted on 2020-07-25
1139 Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF-16-induced longevity
McIntyre, R. L.; Denis, S. W.; Kamble, R.; Petr, M.; Schomakers, B. V.; Jongejan, A.; Scheibye-Knudsen, M.; Houtkooper, R. H.; Janssens, G. E.
10.1101/2020.07.24.219584 — molecular biology — Posted on 2020-07-25
1140 The developmental and genetic architecture of the sexually selected male ornament of swordtails
Schartl, M.; Kneitz, S.; Ormanns, J.; Schmidt, C.; Anderson, J. L.; Amores, A.; Catchen, J. M.; Wilson, C.; Geiger, D.; Du, K.; Garcia-Olazabal, M.; Sudaram, S.; Winkler, C.; Hedrich, R.; Warren, W. C.; Walter, R.; Meyer, A.; Postlethwait, J. H.
10.1101/2020.07.24.219840 — evolutionary biology — Posted on 2020-07-25
1141 Top-down engineering of complex communities by directed evolution
Chang, C.-Y.; Vila, J. C. C.; Bender, M.; Li, R.; Mankowski, M. C.; Bassette, M.; Borden, J.; Golfier, S.; Sanchez, P. G.; Waymack, R.; Zhu, X.; Diaz-Colunga, J.; Estrela, S.; Rebolleda-Gomez, M.; Sanchez, A.
10.1101/2020.07.24.214775 — evolutionary biology — Posted on 2020-07-25
1142 DLX5/6 GABAergic expression affects social vocalization: implications for human evolution
Levi, G.; de Lombares, C.; Giuliani, C.; El Soudany, M.; Aouci, R.; Garagnani, P.; Franceschi, C.; Grimaud-Herve, D.; Narboux-Neme, N.
10.1101/2020.07.24.218065 — evolutionary biology — Posted on 2020-07-25
1143 Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor
Miozzo, F.; Stickley, L.; Tas, D.; Loncle, N.; Nikonenko, I.; Dorcikova, M.; Valencia-Alarcon, E. P.; Bou Dib, P.; Nagoshi, E.
10.1101/2020.07.24.219246 — neuroscience — Posted on 2020-07-25
1144 Left hemispheric deficit in the sustained neuromagnetic response to periodic click trains in children with ASD.
Stroganova, T. A.; Komarov, K. S.; Goiaeva, D. E.; Obukhova, T. S.; Ovsiannikova, T. M.; Prokofyev, A. O.; Orekhova, E.
10.1101/2020.07.24.219410 — neuroscience — Posted on 2020-07-25
1145 An organoid and multi-organ developmental cell atlas reveals multilineage fate specification in the human intestine
Yu, Q.; Kilik, U.; Holloway, E. M.; Tsai, Y.-H.; Wu, A.; Wu, J. H.; Czerwinski, M.; Childs, C.; He, Z.; Glass, I. A.; Higgins, P. D. R.; Treutlein, B.; Spence, J. R.; Camp, J. G.
10.1101/2020.07.24.219147 — developmental biology — Posted on 2020-07-25
1147 Pan-genome-wide analysis of Pantoea ananatis identified genes linked to pathogenicity in onion
Agarwal, G.; Choudhary, D.; Stice, S.; Myers, B.; Gitaitis, R.; Venter, S.; Kvitko, B.; Dutta, B.
10.1101/2020.07.24.219337 — genomics — Posted on 2020-07-24
1148 Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal.
Whiteland, H.; Crusco, A.; Tibble-Howlings, J.; Forde Thomas, J.; Bloemberg, L. W.; Coghlan, A.; Murphy, P.; Hoffmann, K. F.
10.1101/2020.07.24.219311 — zoology — Posted on 2020-07-24
1152 The bakerss yeast Msh4-Msh5 associates with double-strand break hotspots and chromosome axis during meiosis to promote crossovers
Nandanan, K. G.; Pankajam, A. V.; Salim, S.; Shinohara, M.; Lin, G.; Chakraborty, P.; Steinmetz, L. M.; Shinohara, A.; Nishant, K. T.
10.1101/2020.07.24.219295 — genetics — Posted on 2020-07-24
1154 Activating NK- receptors, homing selectins and inhibitory Siglecs recognize EBOLA-GP and HPV-L1NK
Jarahian, M.; Marstaller, K.; Wurmbäck, H.; Banna, N.; Ahani, R.; Etemadzadeh, M. H.; Boller, L. K.; Kayhan, A.; Cid-Arregui, A.; Berger, M. R.; Momburg, F.; Watzl, C.
10.1101/2020.07.24.219329 — immunology — Posted on 2020-07-24
1155 Quantitative detection of sleep apnea with wearable watch device
Hayano, J.; Yamamoto, H.; Nonaka, I.; Komazawa, M.; Itao, K.; Ueda, N.; Tanaka, H.; Yuda, E.
10.1101/2020.07.24.219261 — bioengineering — Posted on 2020-07-24
1156 Activation of pancreatic B-cell genes by multiplex epigenetic CRISPR-editing
Gimenez, C. A.; Curti, L.; Hyon, S. H.; Grosembacher, L.; ROSS, P. J.; Pereyra-Bonnet, F.
10.1101/2020.07.24.214544 — molecular biology — Posted on 2020-07-24
1158 The ecogenomics of dsDNA bacteriophages in feces of stabled and feral horses
Babenko, V. V.; Millard, A.; Kulikov, E. E.; Spasskaya, N. N.; Letarova, M. A.; Konanov, D. N.; Belalov, I. S.; Letarov, A. V.
10.1101/2020.07.24.219436 — genomics — Posted on 2020-07-24
1159 Heterogeneous genetic basis of age at maturity in salmonid fishes
Waters, C. D.; Clemento, A.; Aykanat, T.; Garza, J. C.; Naish, K. A.; Narum, S.; Primmer, C. R.
10.1101/2020.07.24.220111 — evolutionary biology — Posted on 2020-07-24
1160 The BMP antagonist Gremlin1 contributes to the development of cortical excitatory neurons, motor balance and fear responses
Ichinose, M.; Suzuki, N.; Wang, T.; Kobayashi, H.; Vrbanac, L.; Ng, J. Q.; Wright, J. A.; Lannagan, T. R.; Gieniec, K. A.; Lewis, M.; Ando, R.; Enomoto, A.; Koblar, S.; Thomas, P.; Worthley, D. L.; Woods, S. L.
10.1101/2020.07.24.219394 — developmental biology — Posted on 2020-07-24
1163 Germanium nanospheres for ultraresolution picotensiometry of kinesin motors
Sudhakar, S.; Abdosamadi, M. K.; Jachowski, T. J.; Bugiel, M.; Jannasch, A.; Schäffer, E.
10.1101/2020.06.18.159640 — biophysics — Posted on 2020-07-24
1165 Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues in male rats
Liu, C. M.; Hsu, T. M.; Suarez, A. N.; Subramanian, K. S.; Fatemi, R. A.; Cortella, A. M.; Noble, E. E.; Roitman, M. F.; Kanoski, S. E.
10.1101/2020.06.24.169540 — neuroscience — Posted on 2020-07-24
1168 Systematic quantification of health parameters from UK Biobank abdominal MRI using deep learning
Liu, Y.; Basty, N.; Whitcher, B.; Bell, J.; van Bruggen, N.; Thomas, E. L.; Cule, M.
10.1101/2020.07.14.187070 — genetics — Posted on 2020-07-24
1169 INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly
Mascibroda, L. G.; Shboul, M.; Elrod, N. D.; Colleaux, L.; Hamamy, H.; Huang, K.-L.; Peart, N. J.; Singh, M. K.; Lee, H.; Merriman, B.; Jodoin, J. N.; Lee, L. A.; Al-Rawashdeh, B.; Ababneh, O.; El-Khateeb, M.; Fathalla, R.; Escande-Beillard, N.; Nelson, S. F.; Wu, Y.; Tong, L.; Kenney, L. J.; Russell, W. K.; Amiel, J.; Reversade, B.; Wagner, E. J.
10.1101/2020.07.20.209130 — biochemistry — Posted on 2020-07-24
1175 Novel ACE2-IgG1 fusions with improved in vitro and in vivo activity against SARS-CoV2
Iwanaga, N.; Cooper, L.; Rong, L.; Beddingfield, B.; Crabtree, J.; Tripp, R. A.; Qin, X.; Kolls, J.
10.1101/2020.06.15.152157 — immunology — Posted on 2020-07-24
1179 Plexin-B1 mutation drives prostate cancer metastasis
Shorning, B.; Trent, N.; Griffiths, D. F.; Worzfeld, T.; Offermanns, S.; Masters, J.; Clarke, A. R.; Smalley, M. J.; Williamson, M.
10.1101/2020.07.19.203695 — cancer biology — Posted on 2020-07-24
1186 Curation of over 10,000 transcriptomic studies to enable data reuse
Lim, N.; Tesar, S.; Belmadani, M.; Poirier-Morency, G.; Mancarci, B. O.; Sicherman, J.; Jacobson, M.; Leong, J.; Tan, P.; Pavlidis, P.
10.1101/2020.07.13.201442 — bioinformatics — Posted on 2020-07-24
1190 Learning Divisive Normalization in Primary Visual Cortex
Burg, M. F.; Cadena, S. A.; Denfield, G. H.; Walker, E. Y.; Tolias, A. S.; Bethge, M.; Ecker, A. S.
10.1101/767285 — neuroscience — Posted on 2020-07-24
1192 Ghrelin signaling regulates feeding behavior, metabolism, and memory through the vagus nerve
Davis, E. A.; Wald, H. S.; Suarez, A. N.; Zubcevic, J.; Liu, C. M.; Cortella, A. M.; Kamitakahara, A. K.; Polson, J. W.; Arnold, M.; Grill, H. J.; de Lartigue, G.; Kanoski, S. E.
10.1101/2020.06.16.155762 — neuroscience — Posted on 2020-07-24
1193 Clinical and biomarker changes in sporadic Alzheimer's disease
Zhuo, J.; Zhang, Y.; Liu, B.; Liu, Y.; Zhou, X.; Bartlett, P. F.; Jiang, T.; the ADNI,
10.1101/2020.05.08.084293 — neuroscience — Posted on 2020-07-24
1194 A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein to Facilitate the Detection of SARS-CoV-2
Ponce-Rojas, J. C.; Costello, M. S.; Proctor, D. A.; Kosik, K. S.; Wilson, M. Z.; Arias, C.; Acosta-Alvear, D.
10.1101/2020.06.29.178384 — molecular biology — Posted on 2020-07-24
1195 Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors.
Jefferys, S. R.; Burgos, S. D.; Peterson, J.; Selitsky, S. R.; Turner, A.-M.; James, L. I.; Margolis, D. M.; Parker, J.; Browne, E. P.
10.1101/2020.07.24.220012 — microbiology — Posted on 2020-07-24
1197 A diet-dependent enzyme from the human gut microbiome promotes Th17 cell accumulation and colitis
Alexander, M.; Ang, Q. Y.; Nayak, R. R.; Bustion, A. E.; Upadhyay, V.; Pollard, K. S.; Turnbaugh, P. J.
10.1101/766899 — immunology — Posted on 2020-07-24
1202 Reward impacts visual statistical learning
Park, S. H.; Rogers, L. L.; Johnson, M. R.; Vickery, T. J.
10.1101/2020.04.04.025668 — neuroscience — Posted on 2020-07-24
1203 Multi-session visual cortex transcranial random noise stimulation in adults with amblyopia
Donkor, R.; Silva, A. E.; Teske, C.; Wallis-Duffy, M.; Johnson, A.; Thompson, B.
10.1101/679662 — neuroscience — Posted on 2020-07-24
1205 A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material
Rauch, J. N.; Valois, E.; Solley, S. C.; Braig, F.; Audouard, M.; Lach, R. S.; Ponce-Rojas, J. C.; Costello, M. S.; Baxter, N. J.; Kosik, K. S.; Arias, C.; Acosta-Alvear, D.; Wilson, M. Z.
10.1101/2020.04.20.052159 — molecular biology — Posted on 2020-07-24
1206 Host transcriptional responses and SARS-CoV-2 isolates from the nasopharyngeal samples of Bangladeshi COVID-19 patients
Islam, A. B. M. M. K.; Khan, M. A.-A.-K.; Ahmed, R.; Hossain, M. S.; Kabir, S. M. T.; Islam, M. S.; Siddiki, A. M. A. M. Z.
10.1101/2020.07.23.218198 — genomics — Posted on 2020-07-24
1209 SLR-superscaffolder: a de novo scaffolding tool for synthetic long reads using a top-to-bottom scheme
Guo, L.; Xu, M.; Wang, W.; Gu, S.; Zhao, X.; Chen, F.; Wang, O.; Xu, X.; Fan, G.; Deng, L.; Liu, X.
10.1101/762385 — bioinformatics — Posted on 2020-07-24
1211 Tinnitus development is associated with synaptopathy of inner hair cells in Mongolian gerbils
Tziridis, K.; Forster, J.; Wendler, O.; Buchheidt-Doerfler, I.; Krauss, P.; Schilling, A.; Sterna, E.; Schulze, H.
10.1101/304576 — neuroscience — Posted on 2020-07-24
1212 Risk of mitochondrial deletions is affected by the global secondary structure of the mitochondrial genome
Mikhailova, A. A.; Shamanskiy, V.; Ushakova, K.; Mikhailova, A. G.; Oreshkov, S.; Knorre, D.; Tretiakov, E. O.; Zazhytska, M.; Lukowski, S. W.; Liou, C.-W.; Lin, T.-K.; Kunz, W. S.; Reymond, A.; Mazunin, I.; Bazykin, G. A.; Gunbin, K.; Fellay, J.; Tanaka, M.; Khrapko, K.; Popadin, K.
10.1101/603282 — genetics — Posted on 2020-07-24
1213 Structurally distinct endocytic pathways for B cell receptors in B lymphocytes
Roberts, A. D.; Davenport, T. M.; Dickey, A. M.; Ahn, R.; Sochacki, K. A.; Taraska, J. W.
10.1101/394015 — cell biology — Posted on 2020-07-24
1214 Alertness modulates perceptual decision-making
Jagannathan, S. R.; Bareham, C. A.; Bekinschtein, T. A.
10.1101/2020.07.23.218727 — neuroscience — Posted on 2020-07-24
1215 The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection
Beddingfield, B.; Iwanaga, N.; Chapagain, P. P.; Zheng, W.; Roy, C. J.; Hu, T. Y.; Kolls, J.; Bix, G.
10.1101/2020.06.15.153387 — microbiology — Posted on 2020-07-24
1218 Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor
Zhao, P.; Praissman, J. L.; Grant, O. C.; Cai, Y.; Xiao, T.; Rosenbalm, K. E.; Aoki, K.; Kellman, B. P.; Bridger, R.; Barouch, D. H.; Brindley, M. A.; Lewis, N. E.; Tiemeyer, M.; Chen, B.; Woods, R. J.; Wells, L.
10.1101/2020.06.25.172403 — biochemistry — Posted on 2020-07-24
1220 Phenotypic plasticity and partial EMT underlie local invasion and distant metastasis in colon cancer
Sacchetti, A.; Teeuwssen, M.; Verhagen, M.; Joosten, R.; Gusinac, A.; Watson, M. M.; Stabile, R.; Kim, W. K.; Ubink, I.; van de Werken, H. J.; Fumagalli, A.; Paauwe, M.; van Rheenen, J.; Sansom, O. J.; Kranenburg, O.; Fodde, R.
10.1101/2020.07.24.219238 — cancer biology — Posted on 2020-07-24
1224 Unveiling transposable element expression heterogeneity in cell fate regulation at the single-cell level
He, J.; Babarinde, I. A.; Sun, L.; Xu, S.; Chen, R.; Wei, Y.; Li, Y.; Ma, G.; Zhuang, Q.; Hutchins, A.; Chen, J.
10.1101/2020.07.23.218800 — bioinformatics — Posted on 2020-07-24
1225 Structural analysis of SARS-CoV-2 genome and predictions of the human interactome
Vandelli, A.; Monti, M.; Milanetti, E.; Armaos, A.; Rupert, J.; Zacco, E.; Bechara, E.; Delli Ponti, R.; Tartaglia, G. G.
10.1101/2020.03.28.013789 — bioinformatics — Posted on 2020-07-24
1226 Identification, Mapping and Relative Quantitation of SARS-Cov2 Spike Glycopeptides by Mass-Retention Time Fingerprinting
Chalk, R.; Greenland, W.; Moreira, T.; Coker, J.; Mukhopadhyay, S.; Williams, E.; Manning, C.; Bohstedt, T.; McCrorie, R.; Fernandez-Cid, A.; Burgess-Brown, N. A.
10.1101/2020.07.24.217562 — biochemistry — Posted on 2020-07-24
1229 Single-cell landscape of immunological responses in COVID-19 patients
Wang, F.-S.; Zhang, J.-Y.; Wang, X.; Xing, X.; Xu, Z.; Zhang, C.; Song, J.-W.; Fan, X.; Xia, P.; Fu, J.-L.; Wang, S.-Y.; Xu, R.-N.; Dai, X.-P.; Shi, L.; Huang, L.; Jiang, T.-J.; Shi, M.; Zhang, Y.; Zumla, A.; Maeurer, M.; Bai, F.
10.1101/2020.07.23.217703 — immunology — Posted on 2020-07-24
1231 Development of non-transgenic glyphosate tolerant wheat by TILLING
Moehs, C. P.; Austill, W. J.; Facciotti, D.; Holm, A.; Loeffler, D.; Lu, Z.; Mullenberg, J. C.; Slade, A. J.; Steine, M. N.; van Boxtel, J.; McGuire, C.
10.1101/2020.07.23.218883 — plant biology — Posted on 2020-07-24
1232 From people to Panthera: Natural SARS-CoV-2 infection in tigers and lions at the Bronx Zoo
McAloose, D.; Laverack, M.; Wang, L.; Killian, M. L.; Caserta, L. C.; Yuan, F.; Mitchell, P. K.; Queen, K.; Mauldin, M. R.; Cronk, B. D.; Bartlett, S. L.; Sykes, J. M.; Zec, S.; Stokol, T.; Ingerman, K.; Delaney, M. A.; Fredrickson, R.; Ivancic, M.; Jenkins-Moore, M.; Mozingo, K.; Franzen, K.; Hines Bergeson, N.; Goodman, L.; Wang, H.; Fang, Y.; Olmstead, C.; McCann, C.; Thomas, P.; Goodrich, E.; Elvinger, F.; Smith, D. C.; Wang, S.; Slavinski, S.; Calle, P. P.; Terio, K.; Torchetti, M. K.; Diel, D. G.
10.1101/2020.07.22.213959 — pathology — Posted on 2020-07-24
1236 A psychometric platform to collect somatosensory sensations for neuroprosthetic use
Valle, G.; Iberite, F.; Strauss, I.; D'Anna, E.; Granata, G.; Stieglitz, T.; Raspopovic, S.; Petrini, F.; Rossini, P. M.; Micera, S.
10.1101/2020.07.23.218222 — neuroscience — Posted on 2020-07-24
1239 Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability
Kulik, A. A.; Maruszczak, K. K.; Thomas, D. C.; Nabi, N. L. A.; Carr, M.; Bingham, R. J.; Cooper, C. D. O.
10.1101/2020.07.24.219980 — biochemistry — Posted on 2020-07-24
1240 Relevance of SARS-CoV-2 related factors ACE2 and TMPRSS2 expressions in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients
Etiologically Elusive Disorders Research Network (EEDRN), ; Kumar, A.; Faiq, M. A.; Pareek, V.; Raza, K.; Narayan, R. K.; Prasoon, P.; Kumar, P.; Kulandhasamy, M.; Kumari, C.; Kant, K.; Singh, H. N.; Qadri, R.; Pandey, S. N.; Kumar, S.
10.1101/2020.04.14.040204 — pathology — Posted on 2020-07-24
1242 Radiotherapy and chemotherapy alter migration of brain cancer cells before cell death
Merrick, M.; Merrick, M. J.; Weeder, C.; Akhter, H.; Bray, A.; Walther, A.; Nwakama, C.; Bamesberger, J.; Djam, H.; Abid, K.; Ekpenyong, A. E.
10.1101/2020.07.23.218636 — cancer biology — Posted on 2020-07-24
1247 ZNF416 is a pivotal transcriptional regulator of fibroblast mechano-activation
Jones, D. L.; Meridew, J. A.; Ducharme, M. T.; Lydon, K. L.; Choi, K. M.; Caporarello, N.; Tan, Q.; Link, P. A.; Diaz Espinosa, A. M.; Xiong, Y.; Lee, J.-H.; Ye, Z.; Yan, H.; Ordog, T.; Ligresti, G.; Varelas, X.; Tschumperlin, D. J.
10.1101/2020.07.23.218842 — cell biology — Posted on 2020-07-24
1248 Differential Mast Cell Phenotypes in Benign versus Cancer Tissues and Prostate Cancer Oncologic Outcomes
Hempel Sullivan, H.; Maynard, J. P.; Heaphy, C. M.; Lu, J.; De Marzo, A. M.; Lotan, T. L.; Joshu, C. E.; Sfanos, K. S.
10.1101/2020.07.23.216408 — cancer biology — Posted on 2020-07-24
1249 Genomic network analysis of an environmental and livestock IncF plasmid population
Matlock, W.; Chau, K. K.; AbuOun, M.; Stubberfield, E.; Barker, L.; Kavanagh, J.; Pickford, H.; Gilson, D.; Smith, R. P.; Gweon, H. S.; Hoosdally, S. J.; Swann, J.; Sebra, R.; Bailey, M. J.; Peto, T. E. A.; Crook, D. W.; Anjum, M. F.; Read, D. S.; Walker, A. S.; Stoesser, N.; Shaw, L. P.; REHAB Consortium,
10.1101/2020.07.24.215889 — bioinformatics — Posted on 2020-07-24
1251 Actinobacteria challenge the paradigm: a unique protein architecture for a well-known central metabolic complex
Bruch, E. M.; Vilela, P.; Lexa-Sapart, N.; Yang, L.; Raynal, B.; Alzari, P. M.; Bellinzoni, M.
10.1101/2020.07.24.212647 — microbiology — Posted on 2020-07-24
1253 Protein sequence design by explicit energy landscape optimization
Norn, C.; Wicky, B. I. M.; Juergens, D.; Liu, S.; Kim, D.; Koepnick, B.; Anishchenko, I.; Foldit Players, ; Baker, D.; Ovchinnikov, S.
10.1101/2020.07.23.218917 — biophysics — Posted on 2020-07-24
1254 Expression, subcellular localization, and phosphorylation of MK5 in adult cardiac ventricular fibroblasts
Sahadevan, P.; Nawaito, S. A.; Trepanier, J.; Benamar, S.; Sahmi, F.; Theberge-Julien, G.; Villeneuve, L. R.; Gaestel, M.; Tardif, J.-C.; Allen, B. G.
10.1101/2020.07.24.219790 — biochemistry — Posted on 2020-07-24
1255 Phase Unwrapping with a Rapid Opensource Minimum Spanning TreE AlgOrithm (ROMEO)
Dymerska, B.; Eckstein, K.; Bachrata, B.; Siow, B.; Trattnig, S.; Shmueli, K.; Robinson, S. D.
10.1101/2020.07.24.214551 — neuroscience — Posted on 2020-07-24
1257 Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function Following Chronic Traumatic Brain Injury
Badner, A.; Reinhardt, E. K.; Nguyen, T. V.; Midani, N.; Marshall, A. T.; Lepe, C.; Echeverria, K.; Lepe, J.; Torrecampo, V.; Bertan, S. H.; Tran, S. H.; Anderson, A. J.; Cummings, B. J.
10.1101/2020.07.23.212423 — neuroscience — Posted on 2020-07-24
1261 Finding drug targeting mechanisms with genetic evidence for Parkinson's disease -- Mendelian randomization of the druggable genome
Storm, C. S.; Kia, D. A.; Almramhi, M.; Bandres-Ciga, S.; Finan, C.; Hingorani, A. D.; International Parkinson's Disease Genomics Consortium (IPDGC), ; Wood, N. W.
10.1101/2020.07.24.208975 — genetics — Posted on 2020-07-24
1262 An atlas of lamina-associated chromatin across thirteen human cell types reveals cell-type-specific and multiple subtypes of peripheral heterochromatin
Keough, K. C.; Shah, P. P.; Wickramasinghe, N. M.; Dundes, C. E.; Chen, A.; Salomon, R. E. A.; Whalen, S.; Loh, K. M.; Dubois, N.; Pollard, K. S.; Jain, R.
10.1101/2020.07.23.218768 — developmental biology — Posted on 2020-07-24
1263 Retinoic acid rewires the adrenergic core regulatory circuitry of neuroblastoma but can be subverted by enhancer hijacking of MYC or MYCN
Zimmerman, M. W.; Durbin, A. D.; He, S.; Oppel, F.; Shi, H.; Tao, T.; Li, Z.; Berezovskaya, A.; Liu, Y.; Zhang, J.; Young, R.; Abraham, B. J.; Look, A. T.
10.1101/2020.07.23.218834 — cancer biology — Posted on 2020-07-24
1268 Multi-Platform Assessment of DNA Sequencing Performance using Human and Bacterial Reference Genomes in the ABRF Next-Generation Sequencing Study
Foox, J.; Tighe, S. W.; Nicolet, C. M.; Zook, J. M.; Byrska-Bishop, M.; Clarke, W. E.; Khayat, M. M.; Mahmoud, M.; Laaguiby, P. K.; Herbert, Z. T.; Warner, D.; Grills, G. S.; Levy, S.; Schroth, G. P.; Sedlazeck, F. J.; Narzisi, G.; Farmerie, W.; Baldwin, D. A.; Mason, C. E.; Mason, C.
10.1101/2020.07.23.218602 — genomics — Posted on 2020-07-24
1269 Lineage specific transcription factor waves reprogram neuroblastoma from self-renewal to differentiation
Gryder, B.; Banerjee, D.; Bagchi, S.; Liu, Z.; Chen, H.-C.; Xu, M.; Sun, M.; Vaksman, Z.; Diskin, S. J.; Khan, J.; Thiele, C.
10.1101/2020.07.23.218503 — cancer biology — Posted on 2020-07-24
1271 Synergistic Effects of the DRD2/3 Antagonist ONC201 and Radiation in Glioblastoma
He, L.; Bhat, K.; Ioannidis, A.; ZHANG, L.; Nguyen, N. T.; Allen, J. E.; Nghiemphu, P. L.; Cloughesy, T. F.; Liau, L. M.; Kornblum, H. I.; Pajonk, F.
10.1101/2020.07.23.218446 — neuroscience — Posted on 2020-07-24
1275 Balancing selection maintains ancient genetic diversity in C. elegans
Lee, D.; Zdraljevic, S.; Stevens, L.; Wang, Y.; Tanny, R. E.; Crombie, T. A.; Cook, D. E.; Webster, A. K.; Chirakar, R.; Baugh, L. R.; Sterken, M.; Braendle, C.; Felix, M.-A.; Rockman, M.; Andersen, E. C.
10.1101/2020.07.23.218420 — evolutionary biology — Posted on 2020-07-24
1276 Podoplanin drives dedifferentiation and amoeboid invasion of melanoma
de Winde, C. M.; George, S. L.; Arp, A.; Benjamin, A. C.; Crosas-Molist, E.; Hari-Gupta, Y.; Carver, A.; Imperatore, V.; Martinez, V. G.; Sanz-Moreno, V.; Acton, S. E.
10.1101/2020.07.23.218578 — cancer biology — Posted on 2020-07-24
1278 Dielectrophoretic separation of randomly shaped protein particles
Kwak, T. J.; Jung, H.; Allen, B. D.; Demirel, M. C.; Chang, W.-J.
10.1101/2020.07.23.218438 — bioengineering — Posted on 2020-07-24
1280 griPASTA: A hacked kitchen scale for quantification of grip strength in rodents
Homolak, J.; Virag, D.; Kodvanj, I.; Matak, I.; Babic Perhoc, A.; Knezovic, A.; Osmanovic Barilar, J.; Salkovic-Petrisic, M.
10.1101/2020.07.23.217737 — neuroscience — Posted on 2020-07-24
1281 Modulation of Individual Alpha Frequency with tACS shifts Time Perception
Mioni, G.; Shelp, A.; Stanfield-Wiswell, C.; Gladhill, K. A.; Bader, F.; Wiener, M.
10.1101/2020.07.23.218230 — neuroscience — Posted on 2020-07-24
1286 Annotation of Chromatin States in 66 Complete Mouse Epigenomes During Development
van der Velde, A. G.; Fan, K.; Tsuji, J.; Moore, J. E.; Purcaro, M.; Pratt, H.; Weng, Z.
10.1101/2020.07.23.218552 — bioinformatics — Posted on 2020-07-24
1287 A termination-independent role of Rat1 in cotranscriptional splicing
Dhoondia, Z.; Elewa, H.; Malik, M.; Arif, Z.; Pique-Regi, R.; Ansari, A.
10.1101/2020.07.23.218495 — biochemistry — Posted on 2020-07-24
1288 The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle
Furlan-Magaril, M.; Ando-Kuri, M.; Arzate-Mejia, R. G.; Morf, J.; Cairns, J.; Poot- Hernandez, C. A.; Andrews, S.; Varnai, C.; Virk, B.; Wingett, S. W.; Fraser, P.
10.1101/2020.07.23.217992 — genomics — Posted on 2020-07-24
1291 Respiratory bacteria stabilize and promote airborne transmission of influenza A virus
Rowe, H.; Livingston, B.; Margolis, E.; Davis, A.; Meliopoulos, V. A.; Echlin, H.; Shultz-Cherry, S.; Rosch, J.
10.1101/2020.07.23.218131 — microbiology — Posted on 2020-07-24
1295 The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus
Washington, J. T.; Cavender, K. R.; Amukamara, A. U.; McKinney, E. C.; Schmitz, R. J.; Moore, P. J.
10.1101/2020.07.23.218180 — evolutionary biology — Posted on 2020-07-24
1296 Towards Building a Smart Kidney Atlas: Network-based integration of multimodal transcriptomic, proteomic, metabolomic and imaging data in the Kidney Precision Medicine Project
Hansen, J.; Sealfon, R.; Menon, R.; Eadon, M. T.; Lake, B. B.; Steck, B.; Dobi, D.; Parikh, S.; Sidgel, T. K.; Alexandrov, T.; Schroeder, A.; Otto, E. A.; Anderton, C. R.; Barwinska, D.; Zheng, G.; Rose, M. P.; Shapiro, J. P.; Velickovic, D.; Pamreddy, A.; Winfree, S.; He, Y.; de Boer, I. H.; Hodgin, J. B.; Nair, A.; Sharma, K.; Sarwal, M.; Zhang, K.; Himmelfarb, J.; Laszik, Z.; Rovin, B.; Dagher, P. C.; He, J. C.; El-Achkar, T. M.; Jain, S.; Troyanskaya, O. G.; Kretzler, M.; Iyengar, R.; Azeloglu, E. U.
10.1101/2020.07.23.216507 — bioinformatics — Posted on 2020-07-24
1299 A quantitative analysis of the interplay of environment, neighborhood and cell state in 3D spheroids
Zanotelli, V. R. T.; Leutenegger, M.; Lun, X.-K.; Georgi, F.; de Souza, N.; Bodenmiller, B.
10.1101/2020.07.24.219659 — systems biology — Posted on 2020-07-24
1300 Introgression, hominin dispersal and megafaunal survival in Late Pleistocene Island Southeast Asia
Teixeira, J. C.; Jacobs, G. S.; Stringer, C.; Tuke, J.; Hudjashov, G.; Purnomo, G. A.; Sudoyo, H.; Cox, M. P.; Tobler, R.; Turney, C. S.; Cooper, A.; Helgen, K. M.
10.1101/2020.07.24.219048 — evolutionary biology — Posted on 2020-07-24
1301 A semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial maturation
Ostrop, J.; Zwiggelaar, R.; Pedersen, M. T.; Gerbe, F.; Bösl, K.; Lindholm, H. T.; Diez-Sanchez, A.; Parmar, N.; Radetzki, S.; von Kries, J. P.; Jay, P.; Jensen, K. B.; Arrowsmith, C.; Oudhoff, M. J.
10.1101/2020.07.23.217414 — cell biology — Posted on 2020-07-24
1302 Spectrum of pathogenic variants and multiple founder effects in amelogenesis imperfecta associated with MMP20
Nikolopoulos, G.; Smith, C. E. L.; Poulter, J. A.; Murillo, G.; Silva, S.; Brown, C. J.; Day, P. F.; Soldani, F.; Al-Bahlani, S.; Harris, S. A.; O'Connell, M. J.; Inglehearn, C. F.; Mighell, A. J.
10.1101/2020.07.23.217927 — molecular biology — Posted on 2020-07-24
1304 Microbial drama in four acts - Extreme rain events cause cyclic succession in plankton communities
Shabarova, T.; Salcher, M. M.; Porcal, P.; Znachor, P.; Nedoma, J.; Grossart, H.-P.; Seda, J.; Hejzlar, J.; Simek, K.
10.1101/2020.07.23.217935 — ecology — Posted on 2020-07-24
1305 Data-guided Multi-Map variables for ensemble refinement of molecular movies
Vant, J. W.; Sarkar, D.; Fiorin, G.; Skeel, R. D.; Vermaas, J. V.; Singharoy, A.
10.1101/2020.07.23.217794 — biophysics — Posted on 2020-07-24
1306 Detection of homozygous and hemizygous partial exon deletions by whole-exome sequencing
Bigio, B.; Seeleuthner, Y.; Kerner, G.; Migaud, M.; Rosain, J.; Boisson, B.; Nasca, C.; Puel, A.; Bustamante, J.; Casanova, J.-L.; Abel, L.; Cobat, A.
10.1101/2020.07.23.217976 — bioinformatics — Posted on 2020-07-24
1310 Retinal optic flow during natural locomotion
Matthis, J. S.; Muller, K. S.; Bonnen, K. L.; Hayhoe, M. M.
10.1101/2020.07.23.217893 — neuroscience — Posted on 2020-07-24
1312 Platinum resistance induces diverse evolutionary trajectories in high grade serous ovarian cancer
Hoare, J. I.; Hockings, H.; Saxena, J.; Silva, V. L.; Maniati, E.; Mirza, H. B.; Huang, W.; Wood, G. E.; Nicolini, F.; Graham, T. A.; McNeish, I. A.; Lockley, M.
10.1101/2020.07.23.200378 — cancer biology — Posted on 2020-07-24
1313 barcodetrackR: an R package for the interrogation of clonal tracking data
Espinoza, D. A.; Mortlock, R. D.; Koelle, S. J.; Wu, C.; Dunbar, C. E.
10.1101/2020.07.23.212787 — bioinformatics — Posted on 2020-07-24
1314 Inter-annual stability and age-dependent changes in plasma testosterone levels in a longitudinally monitored free-living passerine bird
Tesicky, M.; Krajzingrova, T.; Elias, J.; Velova, H.; Svobodova, J.; Bauerova, P.; Albrecht, T.; Vinkler, M.
10.1101/2020.07.23.217836 — zoology — Posted on 2020-07-24
1317 Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity
Raffa, N.; Won, T. H.; Sukowaty, A.; Candor, K.; Cui, C.; Halder, S.; Dai, M.; Landero Figueroa, J. A.; Schroeder, F. C.; Keller, N.
10.1101/2020.07.23.217810 — microbiology — Posted on 2020-07-24
1318 The effect of absent blood flow on the zebrafish cerebral and trunk vasculature
Kugler, E. C.; Snodgrass, R.; Bowley, G.; Plant, K. C.; Serbanovic-Canic, J.; Evans, P.; Chico, T. J.; Armitage, P.
10.1101/2020.07.23.216192 — developmental biology — Posted on 2020-07-24
1323 Isoprenylcysteine carboxylmethyltransferase basedtherapy for Hutchinson Gilford progeria syndrome
Marcos-Ramiro, B.; Gil-Ordonez, A.; Marin-Ramos, N. I.; Ortega-Nogales, F. J.; Balabasquer, M.; Gonzalo, P.; Rolas, L.; Barkaway, A.; Nourshargh, S.; Andres, V.; Martin-Fontecha, M.; Lopez-Rodriguez, M. L.; Ortega-Gutierrez, S.
10.1101/2020.07.23.217257 — pharmacology and toxicology — Posted on 2020-07-24
1326 Machine intelligence identifies soluble TNFa as a therapeutic target for spinal cord injury
Huie, J. R.; Ferguson, A. R.; Kyritsis, N.; Pan, J.; Irvine, K.-A.; Nielson, J. L.; Schupp, P.; Oldham, M. C.; Gensel, J. C.; Lin, A.; Segal, M. R.; Ratan, R.; Bresnahan, J. C.; Beattie, M.
10.1101/2020.07.22.216572 — neuroscience — Posted on 2020-07-24
1329 Single-cell analysis reveals cellular heterogeneity and molecular determinants of hypothalamic leptin-receptor cells
Kakava Georgiadou, N.; Severens, J.; Moltke-Jorgense, A.; Garner, K. M.; Luijendijk-Berg, M. C. M.; Drkelic, V.; van Dijk, R. E.; Pers, T. H.; Basak, O.; Adan, R. A. H.
10.1101/2020.07.23.217729 — neuroscience — Posted on 2020-07-24
1334 The tree that hides the forest: identification of common predisposing loci in several hematopoietic cancers and several dog breeds.
Hedan, b.; Cadieu, E.; Rimbault, M.; Vaysse, A.; Devauchelle, P.; Botherel, N.; Abadie, J.; Quignon, P.; Derrien, T.; Andre, C.
10.1101/2020.07.23.214007 — genetics — Posted on 2020-07-24
1336 Integrating tracking and resight data from breeding Painted Bunting populations enables unbiased inferences about migratory connectivity and winter range survival
Rushing, C. S.; Van Tatenhove, A. M.; Sharp, A. J.; Ruiz-Gutierrez, V.; Freeman, M. C.; Sykes, P. W.; Given, A. M.; Sillett, T. S.
10.1101/2020.07.23.217554 — ecology — Posted on 2020-07-24
1337 The clinical and molecular significance associated with STING signaling in estrogen receptor-positive early breast cancer
Parkes, E. E.; Humphries, M. P.; Gilmore, E.; Sidi, F. A.; Bingham, V.; Phyu, S. M.; Craig, S. G.; Graham, C.; Miller, J.; Griffin, D.; Kennedy, R. D.; Bakhoum, S. F.; McQuaid, S.; Salto-Tellez, M.; Buckley, N. E.
10.1101/2020.07.23.217398 — cancer biology — Posted on 2020-07-24
1340 Tendon-derived biomimetic surface topographies induce phenotypic maintenance of tenocytes in vitro
Dede Eren, A.; Vasilevich, A. S.; Eren, E. D.; Sudarsanam, P.; Tuvshindorj, U.; de Boer, J.; Foolen, J.
10.1101/2020.07.23.217224 — bioengineering — Posted on 2020-07-24
1341 Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1
Ruegenberg, S.; Mayr, F. A. M. C.; Miethe, S.; Atanassov, I.; Baumann, U.; Denzel, M. S.
10.1101/2020.07.23.216424 — biochemistry — Posted on 2020-07-24
1342 Bimolecule detection for Extracellular Vesicle Screening
Kaneda, H.; Ida, Y.; Kuwahara, R.; Sato, I.; Nakano, T.; Tokuda, H.; Sato, T.; Murakoshi, T.; Honke, K.; Kotani, N.
10.1101/2020.07.23.217018 — biochemistry — Posted on 2020-07-24
1347 Spatiotemporal dynamics between interictal epileptiform discharges and ripples during associative memory processing
Henin, S.; Shankar, A.; Borges, H.; Flinker, A.; Doyle, W.; Friedman, D.; Devinsky, O.; Buzsaki, G.; Liu, A.
10.1101/2020.07.22.216416 — neuroscience — Posted on 2020-07-24
1351 Modular and state-relevant connectivity in high-frequency resting-state BOLD fMRI data: An independent component analysis
DeRamus, T. P.; Faghiri, A.; Iraji, A.; Agcaoglu, O.; Vergara, V. M.; Fu, Z.; Silva, R. F.; Gazula, H.; Stephen, J. M.; Wilson, T. W.; Wang, Y.-P.; Calhoun, V.
10.1101/2020.07.22.212720 — neuroscience — Posted on 2020-07-24
1353 Beneficial contribution of iPSC-progeny to connexin 47 dynamics during demyelination-remyelination
Mozafari, S.; Deboux, C.; Laterza, C.; Ehrlich, M.; Kuhlmann, T.; Martino, G.; Baron-Van Evercooren, A.
10.1101/2020.07.22.216598 — neuroscience — Posted on 2020-07-24
1355 Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders.
Soria, L. R.; Perocheau, D. P.; De Sabbata, G.; De Angelis, A.; Bruno, G.; Polishchuk, E.; Gurung, S.; Paris, D.; Cuomo, P.; Motta, A.; Orford, M.; Eaton, S.; Waddington, S.; Settembre, C.; Muro, A. F.; Baruteau, J.; Brunetti-Pierri, N.
10.1101/2020.07.22.216382 — genetics — Posted on 2020-07-24
1356 Repeated horizontal gene transfer of GALactose metabolism genes violates Dollo's law of irreversible loss
Haase, M. A. B.; Kominek, J.; Opulente, D.; Shen, X.-X.; LaBella, A.; Zhou, X.; DeVirgilio, J.; Hulfachor, A.; Kurtzman, C.; Rokas, A.; Hittinger, C. T.
10.1101/2020.07.22.216101 — genetics — Posted on 2020-07-24
1357 Decadal changes in fire frequencies shift tree communities and functional traits
Pellegrini, A.; Refsland, T.; Averill, C.; Terrer, C.; Staver, C.; Brockway, D.; Caprio, A.; Clatterbuck, W.; Coetsee, C.; Haywood, J.; Hobbie, S.; Hoffmann, W.; Kush, J.; Lewis, T.; Moser, W. K.; Overby, S.; Patterson, W.; Peay, K. G.; Reich, P.; Ryan, C.; Sword, M.; Scharenbroch, B.; Schoennagel, T.; Smith, G.; Stephan, K.; Swanston, C.; Turner, M.; Varner, M.; Jackson, R. B.
10.1101/2020.07.22.216226 — ecology — Posted on 2020-07-24
1368 MicrobeTrace: Retooling Molecular Epidemiology for Rapid Public Health Response
Campbell, E. M.; Boyles, A. A.; Shankar, A.; Kim, J.; Knyazev, S.; Switzer, W. M.
10.1101/2020.07.22.216275 — bioinformatics — Posted on 2020-07-24
1371 Efficiency of a Randomized Confirmatory Basket Trial Design Constrained to Control the False Positive Rate by Indication
He, L.; Ren, Y.; Chen, H.; Guinn, D.; Parashar, D.; Chen, C.; Yuan, S.; Korostyshevskiy, V.; Beckman, R. A.
10.1101/2020.07.22.216127 — cancer biology — Posted on 2020-07-24
1372 Chemotherapeutic Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Fertility and Anticancer Activity
Poley, M.; Shammai, Y.; Kaduri, M.; Koren, L.; Adir, O.; Shklover, J.; Shainsky, J.; Ben-Aharon, I.; Zinger, A.; Schroeder, A.
10.1101/2020.07.22.216168 — bioengineering — Posted on 2020-07-24
1373 Physical modeling of a sliding clamp mechanism for the spreading of ParB at short genomic distance from bacterial centromere sites
Walter, J.-C.; Rech, J.; Walliser, N.-O.; Dorignac, J.; Geniet, F.; Palmeri, J.; Parmeggiani, A.; Bouet, J.-Y.
10.1101/2020.07.22.213413 — systems biology — Posted on 2020-07-24
1376 Spatial phylogenetics of butterflies in relation to environmental drivers and angiosperm diversity across North America
Earl, C.; Belitz, M. W.; Laffan, S. W.; Barve, V.; Barve, N.; Soltis, D. E.; Allen, J. M.; Soltis, P. S.; Mishler, B. D.; Kawahara, A. Y.; Guralnick, R. P.
10.1101/2020.07.22.216119 — ecology — Posted on 2020-07-24
1377 G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT
Castro, M. G.; Alghamri, M. S.; Avvari, R.; Thalla, R.; Kamran, N.; Zhang, L.; Ventosa, M.; Taher, A.; Faisal, S.; Nunez, F.; Garcia-Fabiani, M.; Haase, S.; Carney, S.; Orringer, D.; Hervey-Jumper, S.; Heth, J.; Patil, P. G.; Al-Holou, W.; Merajver, S.; Ulintz, P.; Welch, J.; Gao, C.; Liu, J.; Eddy, K.; Nunez, G.; Hambardzumyan, D.; Lowenstein, P.
10.1101/2020.07.22.215954 — cancer biology — Posted on 2020-07-24
1378 Real-time colorimetric LAMP methodology for quantitative nucleic acids detection at the point-of-care
Papadakis, G.; Pantazis, A. K.; Fikas, N.; Chatziioannidou, S.; Michaelidou, K.; Pogka, V.; Megariti, M.; Vardaki, M.; Giarentis, K.; Heaney, J.; Nastouli, E.; Karamitros, T.; Mentis, A.; Agelaki, S.; Gizeli, E.
10.1101/2020.07.22.215251 — bioengineering — Posted on 2020-07-24
1381 Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity
Luo, H.; Bu, D.; Shao, L.; Li, Y.; Sun, L.; Wang, C.; Wang, J.; Yang, W.; Yang, X.; Dong, J.; Zhao, Y.; Li, F.
10.1101/2020.07.22.215855 — bioinformatics — Posted on 2020-07-24
1389 Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder
Piantadosi, S. C.; McClain, L. L.; Klei, L.; Wang, J.; Springer, S.; Chamberlain, B. L.; Lewis, D. A.; Devlin, B.; Ahmari, S. E.
10.1101/2020.07.23.216697 — neuroscience — Posted on 2020-07-24
1391 The genetic architecture of the sexually selected sword ornament and its evolution in hybrid populations
Powell, D. L.; Payne, C.; Keegan, M.; Banerjee, S. M.; Cui, R.; Andolfatto, P.; Schumer, M.; Rosenthal, G. G.
10.1101/2020.07.23.218164 — evolutionary biology — Posted on 2020-07-24
1394 Modeling Alpha-Synuclein Pathology in a Human Brain-Chip to Assess Blood-Brain Barrier Disruption in Parkinson's Disease
Pediaditakis, I.; Kodella, K. R.; Manatakis, D. V.; Hinojosa, C. D.; Manolakos, E. S.; Rubin, L. L.; Hamilton, G. A.; Karalis, K.
10.1101/2020.07.22.207340 — bioengineering — Posted on 2020-07-24
1395 The biphasic and age-dependent impact of Klotho on hallmarks of aging and skeletal muscle function
Pius, A.; Clemens, Z.; Sivakumar, S.; Sahu, A.; Shinde, S.; Mamiya, H.; Luketich, N.; Cui, J.; Hoeck, J.; Kreuz, S.; Franti, M.; Barchowsky, A.; Ambrosio, F.
10.1101/2020.07.22.207043 — physiology — Posted on 2020-07-24
1397 Cohesin mutations are synthetic lethal with stimulation of WNT signaling
Chin, C. V.; Antony, J.; Ketharnathan, S.; Gimenez, G.; Parsons, K. M.; He, J.; George, A. J.; Braithwaite, A.; Guilford, P.; Hannan, R. D.; Horsfield, J. A.
10.1101/2020.07.23.218875 — cancer biology — Posted on 2020-07-24
1404 Sister chromatid repair maintains genomic integrity during meiosis in Caenorhabditis elegans
Toraason, E.; Clark, C.; Horacek, A.; Glover, M. L.; Salagean, A.; Libuda, D. E.
10.1101/2020.07.22.216143 — genetics — Posted on 2020-07-23
1405 Primate innate immune responses to bacterial and viral pathogens reveals an evolutionary trade-off between strength and specificity
Hawash, M. B. F.; Sanz-Remon, J.; Grenier, J.-C.; Kohn, J.; Yotova, V.; Johnson, Z.; Lanford, R. E.; Brinkworth, J. F.; Barreiro, L. B.
10.1101/2020.07.23.218339 — evolutionary biology — Posted on 2020-07-23
1406 Pure species discriminate against hybrids in the Drosophila melanogaster species subgroup
Serrato-Capuchina, A.; Schwochert, T. D.; Zhang, S.; Roy, B.; Peede, D.; Koppelman, C.; Matute, D. R.
10.1101/2020.07.22.214924 — evolutionary biology — Posted on 2020-07-23
1410 Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of COVID-19 Spike pseudotype virus
Wang, N.; Han, S.; Liu, R.; Meng, L.; He, H.; Zhang, Y.; Wang, C.; Lv, Y.; Wang, J.; Li, X.; Ding, Y.; Fu, J.; Hou, Y.; Lu, W.; Ma, W.; Zhan, Y.; Dai, B.; Zhang, J.; Pan, X.; Hu, S.; Gao, J.; Jia, Q.; Zhang, L.; Ge, S.; Wang, S.; Liang, P.; Hu, T.; Lu, J.; Wang, X.; Zhou, H.; Ta, W.; Wang, Y.; Lu, S.; He, L.
10.1101/2020.06.22.164665 — biochemistry — Posted on 2020-07-23
1412 Pharmacological Insights into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure
Rueda, P.; Merlin, J.; Chimenti, S.; Feletou, M.; Paysant, J.; White, P. J.; Christopoulos, A.; Sexton, P. M.; Summers, R. J.; Charman, W. N.; May, L. T.; Langmead, C. J.
10.1101/2020.07.22.215509 — pharmacology and toxicology — Posted on 2020-07-23
1417 Plant-derived CO2 mediates long-distance host location and quality assessment by a root herbivore
Arce, C. C. M.; Theepan, V.; Schimmel, B. C. J.; Jaffuel, G.; Erb, M.; Machado, R. A. R.
10.1101/2020.03.12.988691 — ecology — Posted on 2020-07-23
1422 Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair
Nakamura, M.; Verboon, J. M.; Allen, T. E.; Abreu-Blanco, M. T.; Liu, R.; Dominguez, A. N. M.; Delrow, J. J.; Parkhurst, S. M.
10.1101/2020.04.06.028662 — cell biology — Posted on 2020-07-23
1428 Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP-43-C pathology
Borghesani, V.; Battistella, G.; Mandelli, M. L.; Welch, A.; Weis, E.; Younes, K.; Neuhaus, J.; Grinberg, L. T.; Seeley, W. W.; Spina, S.; Miller, B. L.; Miller, Z.; Gorno-Tempini, M. L.
10.1101/847582 — neuroscience — Posted on 2020-07-23
1431 Network fingerprint of stimulation induced speech impairment in essential tremor
Petry-Schmelzer, J. N.; Jergas, H.; Thies, T.; Steffen, J. K.; Reker, P.; Dafsari, H. S.; Muecke, D.; Fink, G. R.; Visser-Vandewalle, V.; Dembek, T. A.; Barbe, M. T.
10.1101/2020.02.20.958470 — neuroscience — Posted on 2020-07-23
1435 Litter expansion alters metabolic homeostasis in a sexually divergent manner
Kurup, K.; Mann, S. N.; Jackson, J.; Matyi, S.; Ranjo-Bishop, M.; Freeman, W. M.; Stout, M. B.; Richardson, A.; Unnikrishnan, A.
10.1101/2020.07.23.217307 — molecular biology — Posted on 2020-07-23
1437 Assessment of autism zebrafish mutant models using a high-throughput larval phenotyping platform
Colon-Rodriguez, A.; Uribe-Salazar, J. M.; Weyenberg, K. B.; Sriram, A.; Quezada, A.; Kaya, G.; Jao, E.; Radke, B.; Lein, P. J.; Dennis, M.
10.1101/2020.07.23.217273 — genetics — Posted on 2020-07-23
1438 Serine Phosphorylation Regulates the P-type Potassium pump KdpFABC
Sweet, M. E.; Dubey, V. L.; Zhang, X.; Erdjument-Bromage, H.; Neubert, T. A.; Pedersen, B. P.; Khandelia, H.; Stokes, D. L.
10.1101/2020.01.28.923573 — biophysics — Posted on 2020-07-23
1440 POMK Regulates Dystroglycan Function via LARGE-mediated Elongation of Matriglycan
Walimbe, A. S.; Okuma, H.; Joseph, S.; Yang, T.; Yonekawa, T.; Hord, J. M.; Venzke, D.; Anderson, M. E.; Torelli, S.; Manzur, A.; Devereaux, M.; Cuellar, M.; Prouty, S.; Ocampo Landa, S.; Yu, L.; Xiao, J.; Dixon, J. E.; Muntoni, F.; Campbell, K. P.
10.1101/2020.04.06.007948 — biochemistry — Posted on 2020-07-23
1442 The role of conidia in the dispersal of Ascochyta rabiei
Khaliq, I.; Fanning, J.; Melloy, P.; Galloway, J.; Moore, K.; Burrell, D.; Sparks, A. H.
10.1101/2020.05.12.091827 — plant biology — Posted on 2020-07-23
1443 Catestatin (CST) is a key mediator of the immunoendocrine regulation of cardiovascular function
Ying, W.; Tang, K.; Avolio, E.; Schilling, J. M.; Pasqua, T.; Liu, M. A.; Cheng, H.; Zhang, J.; Mahata, S.; Bandyopadhyay, G. K.; Das, S.; Roth, D. M.; Sahoo, D.; Webster, N. J.; Sheikh, F.; Patel, H. H.; Ghosh, P.; Mahata, S. K.
10.1101/2020.05.12.092254 — physiology — Posted on 2020-07-23
1444 IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.
Laliotis, G. I.; Chavdoula, E.; Paraskevopoulou, M. D.; Kaba, A.; La Ferlita, A.; Anastas, V.; Orlacchio, A.; Taraslia, V.; Vlachos, I.; Capece, M.; Hatzigeorgiou, A.; Palmieri, D. I.; Alaimo, S.; Tsatsanis, C.; Sehgal, L.; Carbone, D. P.; Coppola, V.; Tsichlis, P. N.
10.1101/2020.07.14.195297 — cancer biology — Posted on 2020-07-23
1447 Rqc1 and other yeast proteins containing highly positively charged sequences are not targets of the RQC complex
Barros, G. C.; Requiao, R. D.; Carneiro, R. L.; Masuda, C. A.; Moreira, M. H.; Rossetto, S.; Domitrovic, T.; Palhano, F.
10.1101/849851 — biochemistry — Posted on 2020-07-23
1449 Sex differences in cortisol and memory following acute social stress in amnestic mild cognitive impairment
Murphy, K. J.; Hodges, T. E.; Sheppard, P. A. S.; Troyer, A. K.; Hampson, E.; Galea, L. A.
10.1101/757484 — neuroscience — Posted on 2020-07-23
1451 Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress
Pace, S. A.; Christensen, C.; Schackmuth, M. K.; Wallace, T.; McKlveen, J. M.; Beischel, W.; Morano, R. L.; Scheimann, J. R.; Wilson, S. P.; Herman, J. P.; Myers, B.
10.1101/2020.06.30.181115 — neuroscience — Posted on 2020-07-23
1452 Bacterial dormancy: a subpopulation of viable but non-culturable cells demonstrates better fitness for revival
Wagley, S.; Morcrette, H.; Kovacs-Simon, A.; Yang, Z. R.; Power, A.; Tennant, R. K.; Love, J.; Murray, N.; Titball, R. W.; Butler, C. S.
10.1101/2020.07.23.216283 — microbiology — Posted on 2020-07-23
1453 Soluble corn fiber reduces ovalbumin-induced sinonasal inflammation via the gut microbiota-airway axis
Jaramillo, S. A.; Borsom, E. M.; Orsini, G. M.; Kask, O.; Lee, K.; Hirsch, A. H.; Settles, E.; Shi, X.; Gu, H.; Koppisch, A. T.; Bokulich, N.; Caporaso, J. G.; Cope, E. K.
10.1101/2020.07.23.216754 — microbiology — Posted on 2020-07-23
1455 Antimicrobial prodrug activation by the staphylococcal glyoxalase GloB
Mikati, M. O.; Miller, J. J.; Osbourn, D. M.; Ghebremichael, N.; Shah, I. T.; Burnham, C.-A. D.; Heidel, K. M.; Yan, V. C.; Mueller, F. L.; Dowd, C. S.; Edwards, R. L.; Odom John, A. R.
10.1101/2020.07.23.214460 — microbiology — Posted on 2020-07-23
1456 Genomic epidemiology and evolution of Escherichia coli in wild animals
Murphy, R.; Palm, M.; Mustonen, V.; Warringer, J.; Farewell, A.; Moradigaravand, D.; Parts, L.
10.1101/2020.07.23.216937 — microbiology — Posted on 2020-07-23
1458 The first AI-based mobile application for antibiotic resistance testing
Pascucci, M.; Royer, G.; Adamek, J.; Aristizabal, D.; Bezzarga, A.; Blanche, L.; Boissinot, D.; Boniface-Chang, G.; Brunner, A.; Curel, C.; Dulac-Arnold, G.; Malou, N.; Nordon, C.; Runge, V.; Samson, F.; Sebastian, E.; Soukieh, D.; Vert, J.-P.; Ambroise, C.; Madoui, M.-A.
10.1101/2020.07.23.216929 — microbiology — Posted on 2020-07-23
1460 Niche and local geography shape the pangenome of wastewater- and livestock-associated Enterobacteriaceae
Shaw, L. P.; Chau, K. K.; Kavanagh, J.; AbuOun, M.; Stubberfield, E.; Gweon, H. S.; Barker, L.; Rodger, G.; Bowes, M. J.; Hubbard, A. T. M.; Pickford, H.; Swann, J.; Gilson, D.; Smith, R. P.; Hoosdally, S. J.; Sebra, R.; Brett, H.; Peto, T. E. A.; Bailey, M. J.; Crook, D. W.; Read, D. S.; Anjum, M. F.; Walker, A. S.; Stoesser, N.; REHAB consortium,
10.1101/2020.07.23.215756 — microbiology — Posted on 2020-07-23
1462 The glycoprotease CpaA secreted by medically relevant Acinetobacter species targets multiple O-linked host glycoproteins
Haurat, M. F.; Scott, N. E.; Di Venanzio, G.; Lopez, J.; Pluvinage, B.; Boraston, A.; Ferracane, M. J.; Feldman, M. F.
10.1101/2020.07.22.216978 — microbiology — Posted on 2020-07-23
1463 Oral delivery of SARS-CoV-2 DNA vaccines using attenuated Salmonella typhimurium as a carrier in rat
Yang, D.; Zhu, D.; Meng, Y.; Qimuge, A.; Bilige, B.; Baiyin, T.; Temuqile, T.; Chen, S.; Borjigen, S.; Baigude, H.
10.1101/2020.07.23.217174 — microbiology — Posted on 2020-07-23
1464 SARS-CoV2 genome analysis of Indian isolates and molecular modelling of D614G mutated spike protein with TMPRSS2 depicted its enhanced interaction and virus infectivity
Raghav, S.; Ghosh, A.; Turuk, J.; Kumar, S.; Jha, A.; Madhulika, S.; Priyadarshini, M.; Biswas, V. K.; Shyamli, P. S.; Singh, B.; Singh, N.; Singh, D.; Kiran, A.; Smita, S.; Sabat, J.; Bhattacharya, D.; Dash, R.; Senapati, S.; Beuria, T. K.; Swain, R.; Chattopadhyay, S.; Syed, G. H.; Dixit, A.; Prasad, P.; Pati, S.; Parida, A.
10.1101/2020.07.23.217430 — genomics — Posted on 2020-07-23
1465 Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy
Patterson, E. I.; Elia, G.; Grassi, A.; Giordano, A.; Desario, C.; Medardo, M.; Smith, S. L.; Anderson, E. R.; Prince, T.; Patterson, G. T.; Lorusso, E.; Lucente, M. S.; Lanave, G.; Lauzi, S.; Bonfanti, U.; Stranieri, A.; Martella, V.; Solari Basano, F.; Barrs, V. R.; Radford, A. D.; Agrimi, U.; Hughes, G. L.; Paltrinieri, S.; Decaro, N.
10.1101/2020.07.21.214346 — microbiology — Posted on 2020-07-23
1468 A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing
Kellner, M. J.; Ross, J. J.; Schnabl, J.; Dekens, M. P. S.; Heinen, R.; Grishkovskaya, I.; Bauer, B.; Stadlmann, J.; Menendez-Arias, L.; Fritsche-Polanz, R.; Traugott, M.; Seitz, T.; Zoufaly, A.; Foedinger, M.; Wenisch, C.; Zuber, J.; Vienna Covid-19 Diagnostics Initiative (VCDI), ; Pauli, A.; Brennecke, J.
10.1101/2020.06.23.166397 — molecular biology — Posted on 2020-07-23
1469 Pre-existing and de novo humoral immunity to SARS-CoV-2 in humans
Ng, K. W.; Faulkner, N.; Cornish, G.; Rosa, A.; Harvey, R.; Hussain, S.; Ulferts, R.; Earl, C.; Wrobel, A.; Benton, D.; Roustan, C.; Bolland, W.; Thompson, R.; Agua-Doce, A.; Hobson, P.; Heaney, J.; Rickman, H.; Paraskevopoulou, S.; Houlihan, C. F.; Thomson, K.; Sanchez, E.; Brealey, D.; Shin, G. Y.; Spyer, M. J.; Joshi, D.; O'Reilly, N.; Walker, P. A.; Kjaer, S.; Riddell, A.; Moore, C.; Jebson, B. R.; Marshall, L. R.; Wilkinson, M. G.; Rosser, E. C.; Radziszewska, A.; Peckham, H.; Ciurtin, C.; Wedderburn, L. R.; Beale, R.; Swanton, C.; Gandhi, S.; Stockinger, B.; McCauley, J.; Gamblin, S.; Mc
10.1101/2020.05.14.095414 — immunology — Posted on 2020-07-23
1470 Analysis of continuous neuronal activity evoked by natural speech with computational corpus linguistics methods
Schilling, A.; Tomasello, R.; Henningsen-Schomers, M. R.; Zankl, A.; Surendra, K.; Haller, M.; Karl, V.; Uhrig, P.; Maier, A.; Krauss, P.
10.1101/2020.04.21.052720 — neuroscience — Posted on 2020-07-23
1473 Explainable AI reveals key changes in skin microbiome associated with menopause, smoking, aging and skin hydration
Carrieri, A. P.; Haiminen, N.; Maudsley-Barton, S.; Gardiner, L.-J.; Murphy, B.; Mayes, A.; Paterson, S.; Grimshaw, S.; Winn, M.; Shand, C.; Rowe, W.; Hawkins, S.; MacGuire-Flanagan, A.; Tazzioli, J.; Kenny, J.; Parida, L.; Hoptroff, M.; Pyzer-Knapp, E. O.
10.1101/2020.07.02.184713 — bioinformatics — Posted on 2020-07-23
1474 Insights on cross-species transmission of SARS-CoV-2 from structural modeling
Rodrigues, J. P.; Barrera-Vilarmau, S.; Teixeira, J. M.; Seckel, E.; Kastritis, P. L.; Levitt, M.
10.1101/2020.06.05.136861 — bioinformatics — Posted on 2020-07-23
1477 Neuromuscular fatigue and recovery after strenuous exercise depends on skeletal muscle size and stem cell characteristics
Baumert, P.; Temple, S.; Stanley, M. J.; Cocks, M.; Strauss, J. A.; Shepherd, S. O.; Drust, B.; Lake, M. J.; Stewart, C. E.; Erskine, R. M.
10.1101/740266 — physiology — Posted on 2020-07-23
1480 Prion cross-seeding between fungal and mammalian amyloid signaling motifs
Bardin, T.; Daskalov, A.; Barrouilhet, S.; Granger-Farbos, A.; Salin, B.; Blancard, C.; Saupe, S. J.; Coustou, V.
10.1101/2020.07.22.215483 — microbiology — Posted on 2020-07-23
1481 Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2
An, X.; Martinez, M. P.; Rezvan, A.; Fathi, M.; Singh, S.; Biswas, S.; Pourpak, M.; Yee, C.; Liu, X.; Varadarajan, N.
10.1101/2020.07.23.212357 — immunology — Posted on 2020-07-23
1484 Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy
Shabalin, I. G.; Czub, M. P.; Majorek, K. A.; Brzezinski, D.; Grabowski, M.; Cooper, D. R.; Panasiuk, M.; Chruszcz, M.; Minor, W.
10.1101/2020.07.21.212704 — pharmacology and toxicology — Posted on 2020-07-23
1485 Rapid in vitro assays for screening neutralizing antibodies and antivirals against SARS-CoV-2
Oark, J.-G.; Oladduni, F. S.; Chiem, K.; Ye, C.; Pipenbrink, M.; Moran, T.; Walter, M.; Kobie, J.; Martinez-Sobrido, L.
10.1101/2020.07.22.216648 — microbiology — Posted on 2020-07-23
1486 SARS-CoV-2 receptor Angiotensin I-Converting Enzyme type 2 is expressed in human pancreatic islet β-cells and is upregulated by inflammatory stress
Fignani, D.; Licata, G.; Brusco, N.; Nigi, L.; Grieco, G. E.; Marselli, L.; Overbergh, L.; Gysemans, C.; Colli, M. L.; Marchetti, P.; Mathieu, C.; Eizirik, D. L.; Sebastiani, G.; Dotta, F.
10.1101/2020.07.23.208041 — cell biology — Posted on 2020-07-23
1492 Constructing and Optimizing 3D Atlases From 2D Data With Application to the Developing Mouse Brain
Young, D. M.; Fazel Darbandi, S.; Schwartz, G.; Bonzell, Z.; Yuruk, D.; Nojima, M.; Gole, L.; Rubenstein, J. L.; Yu, W.; Sanders, S. J.
10.1101/2020.04.01.017665 — developmental biology — Posted on 2020-07-23
1493 De novo protein design by deep network hallucination
Anishchenko, I.; Chidyausiku, T. M.; Ovchinnikov, S.; Pellock, S. J.; Baker, D.
10.1101/2020.07.22.211482 — bioengineering — Posted on 2020-07-23
1498 Microtubules tune mechanosensitive cell responses
Seetharaman, S.; Vianay, B.; Roca, V.; De Pascalis, C.; Boëda, B.; Dingli, F.; Loew, D.; Vassilopoulos, S.; Thery, M.; Etienne-Manneville, S.
10.1101/2020.07.22.205203 — cell biology — Posted on 2020-07-23
1499 Increased isoDGR motifs in plasma fibronectin are associated with atherosclerosis through facilitation of vascular fibrosis
Park, J. E.; Guo, X.; Liou, K. C. K.; Lynn, S. E.; Ng, S. S.; Meng, W.; Lim, S. C.; Leow, M. K.-S.; Richards, A. M.; Pennington, D. J.; McCarthy, N. E.; de Kleijn, D. P. V.; Sorokin, V.; Ho, H. H.; Sze, S. K.
10.1101/2020.07.21.213397 — biochemistry — Posted on 2020-07-23
1501 Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism
Han, Y.; Zhuang, Q.; Sun, B.; Lv, W.; Wang, S.; Xiao, Q.; Chi, P.; Pang, B.; Zhou, Y.; Wang, F.; Wang, Q.; Li, Z.; Zhu, L.; Li, F.; Deng, D.; Chiang, Y.-C.; Li, Z.; Ren, R.
10.1101/2020.07.23.217620 — biochemistry — Posted on 2020-07-23
1502 Chloroplast-derived photo-oxidative stress causes changes in H2O2 and EGSH in other subcellular compartments
Ugalde, J. M.; Fuchs, P.; Nietzel, T.; Cutolo, E.; Vothknecht, U. C.; Holuigue, L.; Schwarzländer, M.; Müller-Schüssele, S. J.; Meyer, A. J.
10.1101/2020.07.20.212670 — plant biology — Posted on 2020-07-23
1503 A zebrafish model of Granulin deficiency reveals essential roles in myeloid cell differentiation
Espin Palazon, R.; Campbell, C. A.; Fursova, O.; Cheng, X.; Snella, E.; McCune, A.; Li, L.; Solchenberger, B.; Schmid, B.; Sahoo, D.; Morton, M.; Traver, D.
10.1101/2020.07.23.217067 — cell biology — Posted on 2020-07-23
1504 Single-cell multimodal glioma analyses reveal epigenetic regulators of cellular plasticity and environmental stress response
Johnson, K. C.; Anderson, K. J.; Courtois, E. T.; Barthel, F.; Varn, F. S.; Luo, D.; Seignon, M.; Yi, E.; Kim, H.; Estecio, M.; Tang, M.; Navin, N.; Maurya, R.; Ngan, C.; Verburg, N.; De Witt Hamer, P. C.; Bulsara, K.; Samuels, M.; Das, S.; Robson, P.; Verhaak, R.
10.1101/2020.07.22.215335 — cancer biology — Posted on 2020-07-23
1506 DNA methylation is a key mechanism for maintaining monoallelic expression on autosomes
Gupta, S.; Lafontaine, D. L.; Vigneau, S.; Vinogradova, S.; Mendelevich, A.; Igarashi, K. J.; Bortvin, A.; Alves-Pereira, C. F.; Clement, K.; Pinello, L.; Gnirke, A.; Long, H.; Gusev, A.; Nag, A.; Gimelbrant, A. A.
10.1101/2020.02.20.954834 — genomics — Posted on 2020-07-23
1508 Identification of a new regulation pathway of EGFR and E-cadherin dynamics
PROUX-GILLARDEAUX, V.; ADVEDISSIAN, T.; PERIN, C.; GELLY, J.-C.; VIGUIER, M.; DESHAYES, F.
10.1101/2020.07.22.215806 — cell biology — Posted on 2020-07-23
1509 ERRα coordinates actin and focal adhesion dynamics
Tribollet, V.; Cerutti, C.; Geloen, A.; Danty-Berger, E.; De Mets, R.; Balland, m.; Courchet, J.; Vanacker, J.-M.; Forcet, C.
10.1101/2020.07.22.216085 — cell biology — Posted on 2020-07-23
1511 Selective targeting of non-centrosomal AURKA functions through use of a novel targeted protein degradation tool
Wang, R. K.; Abdelbaki, A. M.; Ascanelli, C.; Fung, A. Y.; Rasmusson, T.; Roberts, K.; Lindon, C.
10.1101/2020.07.22.215814 — cell biology — Posted on 2020-07-23
1512 Characterization of two novel proteins involved in mitochondrial DNA anchoring
Amodeo, S.; Hoffmann, A.; Fradera-Sola, A.; Bregy, I.; Baudouin, H.; Haenni, B.; Zuber, B.; Butter, F.; Ochsenreiter, T.
10.1101/2020.07.22.215871 — cell biology — Posted on 2020-07-23
1514 Coupling between lipid miscibility and phosphotyrosine driven protein condensation at the membrane
Chung, J. K.; Huang, W. Y. C.; Carbone, C. B.; Nocka, L. M.; Parikh, A. N.; Vale, R.; Groves, J. T.
10.1101/2020.07.22.215970 — biophysics — Posted on 2020-07-23
1515 Zinc shapes the folding landscape of p53 and establishes a new pathway for reactivating structurally diverse p53 mutants
Blanden, A. R.; Yu, X.; Blayney, A. J.; Demas, C.; Ha, J.-H.; Liu, Y.; Withers, T.; Carpizo, D. R.; Loh, S. N.
10.1101/2020.07.23.217695 — biochemistry — Posted on 2020-07-23
1516 Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility
Erdmann, R.; Neuhaus, A.; Bruehl, L.; Bharti, P.; Schliebs, W.; Sattler, M.; Kooshapur, H.; Suda, J.; Jung, M.
10.1101/2020.07.23.218024 — biochemistry — Posted on 2020-07-23
1517 Direct morpho-chemical characterization of elusive plant residues from Aurignacian Pontic Steppe ground stones
Birarda, G.; Cagnato, C.; Pantyukhina, I.; Stani, C.; Cefarin, N.; Sorrentino, G.; Badetti, E.; Marcomini, A.; Lubritto, C.; Khlopacev, G.; Covalenco, S.; Obada, T.; Skakun, N.; Vaccari, L.; Longo, L.
10.1101/2020.07.23.212324 — paleontology — Posted on 2020-07-23
1519 The supramolecular landscape of growing human axons
Hoffmann, P. C.; Giandomenico, S. L.; Ganeva, I.; Wozny, M. R.; Sutcliffe, M.; Kukulski, W.; Lancaster, M. A.
10.1101/2020.07.23.216622 — cell biology — Posted on 2020-07-23
1524 From people to Panthera: Natural SARS-CoV-2 infection in tigers and lions at the Bronx Zoo
McAloose, D.; Laverack, M.; Wang, L.; Killian, M. L.; Caserta, L. C.; Mitchell, P. K.; Queen, K.; Mauldin, M. R.; Cronk, B. D.; Bartlett, S. L.; Sykes, J. M.; Zec, S.; Ingerman, K.; Stokol, T.; Frederikson, R.; Delaney, M. A.; Ivancic, M.; Jenkins-Moore, M.; Mozingo, K.; Franzen, K.; Hines Bergeson, N.; Goodman, L.; Wang, H.; Wang, S.; Yuan, F.; Fang, Y.; Olmstead, C.; McCann, C.; Thomas, P.; Goodrich, E.; Elvinger, F.; Slavinski, S.; Smith, D. C.; Calle, P. P.; Terio, K.; Torchetti, M. K.; Diel, D. G.
10.1101/2020.07.22.213959 — pathology — Posted on 2020-07-23
1528 Ventral Tegmental Area GABA, glutamate, and glutamate-GABA neurons are heterogenous in their electrophysiological and pharmacological properties
Miranda-Barrientos, J. A.; Chambers, I.; Mongia, S.; Liu, B.; Wang, H.-L.; Mateo-Semidey, G. E.; Margolis, E. B.; Zhang, S.; Morales, M.
10.1101/2020.07.22.216093 — neuroscience — Posted on 2020-07-23
1529 Expectancy changes the self-monitoring of voice identity
Johnson, J. F.; Belyk, M.; Schwartze, M.; Pinheiro, A. P.; Kotz, S. A.
10.1101/2020.07.22.215350 — neuroscience — Posted on 2020-07-23
1530 Deep sampling and pooled amplicon sequencing reveals hidden genic variation in heterogeneous rye accessions
Hawliczek, A.; Bolibok, L.; Tofil, K.; Borzecka, E.; Jankowicz-Cieslak, J.; Gawronski, P.; Kral, A.; Till, B. J.; Bolibok-Bragoszewska, H.
10.1101/2020.02.20.958181 — genomics — Posted on 2020-07-22
1531 The roles of history, chance, and natural selection in the evolution of antibiotic resistance
Santos-Lopez, A.; Marshall, C. W.; Welp, A. L.; Turner, C. B.; Rasero, J.; Cooper, V. S.
10.1101/2020.07.22.216465 — evolutionary biology — Posted on 2020-07-22
1533 A modular two yeast species secretion system for the production and preparative application of fungal peroxygenases
Puellmann, P.; Knorrscheidt, A.; Muench, J.; Palme, P. R.; Hoehenwarter, W.; Marillonnet, S.; Alcalde, M.; Westermann, B.; Weissenborn, M. J.
10.1101/2020.07.22.216432 — synthetic biology — Posted on 2020-07-22
1535 Genome-informed microscopy reveals infections of uncultivated carbon-fixing archaea by lytic viruses in Earth's crust
Rahlff, J.; Turzynski, V.; Esser, S. P.; Monsees, I.; Bornemann, T. L.; Figueroa-Gonzalez, P. A.; Schulz, F. L. V.; Woyke, T.; Klingl, A.; Moraru, C.; Probst, A. J.
10.1101/2020.07.22.215848 — microbiology — Posted on 2020-07-22
1536 Metronomic doses and drug schematic combination response tested within microfluidic models for the treatment of breast cancer cells (JIMT-1).
Rosero, G. I.; Pattarone, G.; Penaherrera, A.; Pilz, J. F.; Bödecker, J.; Lerner, B.; Mertelsmann, R.; Perez, M.; Follo, M.
10.1101/2020.07.16.188748 — cancer biology — Posted on 2020-07-22
1537 Integration of plant metabolic complexity into fitness-relevant foraging by a specialist herbivore
Machado, R. A. R.; Theepan, V.; Robert, C. A. M.; Zuest, T.; Hu, L.; Su, Q.; Schimmel, B. C. J.; Erb, M.
10.1101/2020.07.13.200618 — animal behavior and cognition — Posted on 2020-07-22
1538 CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations
Leader, A. M.; Grout, J. A.; Chang, C.; Maier, B.; Tabachnikova, A.; Walker, L.; Lansky, A.; LeBerichel, J.; Malissen, N.; Davila, M.; Martin, J.; Magri, G.; Tuballes, K.; Zhoa, Z.; Petralia, F.; Samstein, R.; D'Amore, N. R.; Thurston, G.; Kamphorst, A.; Wolf, A.; Flores, R.; Wang, P.; Beasley, M. B.; Salmon, H.; Rahman, A. H.; Marron, T. U.; Kenigsberg, E.; Merad, M.
10.1101/2020.07.16.207605 — immunology — Posted on 2020-07-22
1543 Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization
Matsumura, K.; Shimomura, T.; Kubo, Y.; Oka, T.; Kobayashi, N.; Imai, S.; Yanase, N.; Akimoto, M.; Fukuda, M.; Yokogawa, M.; Ikeda, K.; Kurita, J.-i.; Nishimura, Y.; Shimada, I.; Osawa, M.
10.1101/2020.07.22.215491 — molecular biology — Posted on 2020-07-22
1544 Prion cross-seeding between fungal and mammalian amyloid signaling motifs
Bardin, T.; Daskalov, A.; Barrouilhet, S.; Granger-Farbos, A.; Salin, B.; Blancard, C.; Saupe, S. J.; Coustou, V.
10.1101/2020.07.22.215483 — microbiology — Posted on 2020-07-22
1549 FERONIA regulates FLS2 plasma membrane nanoscale dynamics to modulate plant immune signaling
Gronnier, J.; Franck, C. M.; Stegmann, M.; DeFalco, T.; Abarca, A.; Duenser, K.; Lin, W.; Yang, Z.; Kleine-Vehn, J.; Ringli, C.; zipfel, c.
10.1101/2020.07.20.212233 — plant biology — Posted on 2020-07-22
1550 Activation of the Crtc2/Creb1 transcriptional network in skeletal muscle enhances weight loss during intermittent fasting
Bruno, N.; Nwachukwu, J. C.; Srinivasan, S.; Sturgill, D.; Hager, G.; Hurst, S.; Sheu, S.-S.; Conkright, M.; Nettles, K. W.
10.1101/2020.06.27.175323 — physiology — Posted on 2020-07-22
1554 An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes
Perez-Sepulveda, B. M.; Heavens, D.; Pulford, C. V.; Predeus, A. V.; Low, R.; Webster, H.; Schudoma, C.; Rowe, W.; Lipscombe, J.; Watkins, C.; Kumwenda, B.; Shearer, N.; Costigan, K.; Baker, K. S.; Feasey, N. A.; Hinton, J. C. D.; Hall, N.; The 10KSG consortium,
10.1101/2020.07.22.200840 — microbiology — Posted on 2020-07-22
1556 A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
Scott, D. E.; Francis-Newton, N. J.; Marsh, M. E.; Coyne, A. G.; Fischer, G.; Moschetti, T.; Bayly, A. R.; Sharpe, T. D.; Haas, K. T.; Barber, L.; Valenzano, C.; Srinivasan, R.; Huggins, D. J.; Ehebauer, M.; Esposito, A.; Pellegrini, L.; Perrior, T.; McKenzie, G.; Blundell, T. L.; Hyvonen, M.; Skidmore, J.; Venkitaraman, A. R.; Abell, C.
10.1101/2020.07.15.200709 — cancer biology — Posted on 2020-07-22
1560 Positive effect of combining high pressure and biopreservation treatments on lowering the bacterial growth during storage of diced cooked ham with reduced nitrite salt
Chaillou, S.; Ramaroson, M.; Coeuret, G.; Rossero, A.; Anthoine, V.; Champomier-Verges, M.; Moriceau, N.; Reze, S.; Martin, J.-L.; Guillou, S.; Zagorec, M.
10.1101/2020.07.22.215863 — microbiology — Posted on 2020-07-22
1561 Genome-wide mutagenesis identifies factors involved in Enterococcus faecalis vaginal adherence and persistence
Alhajjar, N.; Chatterjee, A.; Spencer, B. L.; Burcham, L. R.; Willett, J. L. E.; Dunny, G. M.; Duerkop, B. A.; Doran, K. S.
10.1101/2020.04.30.069468 — microbiology — Posted on 2020-07-22
1562 DNA methylation site loss for plasticity-led novel trait genetic fixation
Katsumura, T.; Sato, S.; Yamashita, K.; Oda, S.; Gakuhari, T.; Tanaka, S.; Fujitani, K.; Nishimaki, T.; Imai, T.; Yoshiura, Y.; Takeshima, H.; Hashiguchi, Y.; Mitani, H.; Ogawa, M.; Takeuchi, H.; Oota, H.
10.1101/2020.07.09.194738 — evolutionary biology — Posted on 2020-07-22
1563 A modelling framework for the prediction of the herd-level probability of infection from longitudinal data
Madouasse, A.; Mercat, M.; van Roon, A.; Graham, D.; Guelbenzu, M.; Santman Berends, I.; van Schaik, G.; Nielen, M.; Frössling, J.; Agren, E.; Humphry, R.; Eze, J.; Gunn, G.; Henry, M. K.; Gethmann, J.; More, S. J.; Fourichon, C.
10.1101/2020.07.10.197426 — bioinformatics — Posted on 2020-07-22
1564 INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly
Mascibroda, L. G.; Shboul, M.; Elrod, N. D.; Colleaux, L.; Hamamy, H.; Huang, K.-L.; Peart, N. J.; Singh, M. K.; Lee, H.; Merriman, B.; Jodoin, J. N.; Lee, L. A.; Al-Rawashdeh, B.; Ababneh, O.; El-Khateeb, M.; Fathalla, R.; Escande-Beillard, N.; Nelson, S. F.; Wu, Y.; Tong, L.; Kenney, L. J.; Russell, W. K.; Amiel, J.; Reversade, B.; Wagner, E. J.
10.1101/2020.07.20.209130 — biochemistry — Posted on 2020-07-22
1565 How repair-or-dispose decisions under stress can initiate disease progression
Nold, A.; Batulin, D.; Birkner, K.; Bittner, S.; Tchumatchenko, T.
10.1101/828053 — systems biology — Posted on 2020-07-22
1567 FasR regulates fatty acid biosynthesis and is essential for virulence of Mycobacterium tuberculosis
Mondino, S.; Vazquez, C. L.; Cabruja, M.; Sala, C.; Cazenave-Gassiot, A.; Blanco, F. C.; Wenk, M. R.; Cole, S.; Bigi, F.; Gramajo, H.; Gago, G.
10.1101/2020.06.08.140004 — microbiology — Posted on 2020-07-22
1573 An online headphone screening test based on dichotic pitch
Milne, A. E.; Bianco, R.; Poole, K. C.; Zhao, S.; Billig, A. J.; Chait, M.
10.1101/2020.07.21.214395 — neuroscience — Posted on 2020-07-22
1575 CglB adhesins secreted at bacterial focal adhesions mediate gliding motility
Islam, S. T.; My, L.; Jolivet, N. Y.; Belgrave, A. M.; Fleuchot, B.; Brasseur, G.; Faure, L. M.; Sharma, G.; Lemon, D. J.; Saidi, F.; Fiche, J.-B.; Bratton, B. P.; Singer, M.; Garza, A. G.; Nollmann, M.; Shaevitz, J. W.; Mignot, T.
10.1101/2020.07.22.216333 — microbiology — Posted on 2020-07-22
1576 Intra- and extra-cellular environments contribute to the fate of HIV-1 infection
Ratnapriya, S.; Harris, M.; Chov, A.; Vrbanac, V.; Deruaz, M.; Sodroski, J.; Herschhorn, A.
10.1101/2020.07.22.195719 — microbiology — Posted on 2020-07-22
1577 Selective expression of variant surface antigens enables Plasmodium falciparum to evade immune clearance in vivo
Chew, M.; Ye, W.; Omelianczyk, R. I.; Pasaje, C. F. A.; Hoo, R.; Chen, Q.; Niles, J. C.; Chen, J.; Preiser, P.
10.1101/2020.07.22.215640 — microbiology — Posted on 2020-07-22
1579 Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
Tian, R.; Abarientos, A.; Hong, J.; Hashemi, S. H.; Yan, R.; Nalls, M. A.; Singleton, A. B.; Xu, K.; Faghri, F.; Kampmann, M.
10.1101/2020.06.27.175679 — genomics — Posted on 2020-07-22
1580 Disease-relevant single cell photonic signatures identify S100β stem cells and their myogenic progeny in vascular lesions
Molony, C.; King, D.; di Luca, M.; Olayinka, A.; Hakimjavadi, R.; Julius, L. A.; Fitzpatrick, E.; Gusti, Y.; Burtenshaw, D.; Healy, K.; Finlay, E. K.; Kernan, D.; Llobera, A.; Liu, W.; Morrow, D.; Redmond, E. M.; Ducree, J.; Cahill, P. A.
10.1101/2020.05.13.093518 — cell biology — Posted on 2020-07-22
1581 Transdiagnostic dimensions of psychopathology explain individuals' unique deviations from normative neurodevelopment in brain structure
Parkes, L.; Moore, T. M.; Calkins, M. E.; Cook, P. A.; Cieslak, M.; Roalf, D. R.; Wolf, D. H.; Gur, R. C.; Gur, R. E.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2020.06.11.147009 — neuroscience — Posted on 2020-07-22
1585 Species-Specific Responses of Bird Song Output in the Presence of Drones
Wilson, A. M.; Boyle, K. S.; Gilmore, J. L.; Kiefer, C. J.; Walker, M. F.
10.1101/2020.07.19.211045 — ecology — Posted on 2020-07-22
1588 CoExp Web, a web tool for the exploitation of co-expression networks
Garcia, S.; Gil, A. L.; Cisterna, A.; Jurado, F.; Reynolds, R. H.; North America Brain Expression Consortium (NABEC), ; Cookson, M. R.; Hardy, J.; Ryten, M.; Botia, J. A.
10.1101/2020.06.29.176057 — bioinformatics — Posted on 2020-07-22
1589 Temperature-dependent fasciation mutants connect mitochondrial RNA processing to the control of cell proliferation during lateral root morphogenesis
Otsuka, K.; Mamiya, A.; Konishi, M.; Nozaki, M.; Kinoshita, A.; Tamaki, H.; Arita, M.; Saito, M.; Yamamoto, K.; Hachiya, T.; Noguchi, K.; Ueda, T.; Yagi, Y.; Kobayashi, T.; Nakamura, T.; Sato, Y.; Hirayama, T.; Sugiyama, M.
10.1101/2020.06.09.141382 — plant biology — Posted on 2020-07-22
1590 Timing of readiness potentials reflect a decision-making process in the human brain
Lui, K. K.; Nunez, M. D.; Cassidy, J. M.; Vandekerckhove, J.; Cramer, S. C.; Srinivasan, R.
10.1101/338806 — neuroscience — Posted on 2020-07-22
1591 Genome-resolved viral ecology in a marine oxygen minimum zone (OMZ)
Vik, D.; Sun, C. L.; Gazitua, M. C.; Aldunate, M.; Mulholland, M. R.; Ulloa, O.; Sullivan, M. B.
10.1101/2020.07.22.215772 — microbiology — Posted on 2020-07-22
1595 Modular cell-free expression plasmids to accelerate biological design in cells
Karim, A.; Liew, E.; Garg, S.; Vögeli, B.; Rasor, B.; Gonnot, A.; Pavan, M.; Juminaga, A.; Simpson, S. D.; Köpke, M.; Jewett, M. C.
10.1101/2020.07.22.216267 — synthetic biology — Posted on 2020-07-22
1599 Virus-free and live-cell visualizing SARS-CoV-2 cell entry for studies of neutralizing antibodies and compound inhibitors
Zhang, Y.; Wang, S.; Wu, Y.; Hou, W.; Yuan, L.; Sheng, C.; Wang, J.; Ye, J.; Zheng, Q.; Ma, J.; Xu, J.; Wei, M.; Li, Z.; Nian, S.; Xiong, H.; Zhang, L.; Shi, Y.; Fu, B.; Cao, J.; Yang, C.; Li, Z.; Yang, T.; Liu, L.; Yu, H.; Hu, J.; Ge, S.; Chen, Y.; Zhang, T.; Zhang, J.; Cheng, T.; Yuan, Q.; Xia, N.
10.1101/2020.07.22.215236 — microbiology — Posted on 2020-07-22
1601 The discovery of a recombinant SARS2-like CoV strain provides insights into SARS and COVID-2019 pandemics
Li, X.; Jin, X.; Chen, S.; Wang, L.; Yau, T. O.; Yang, J.; Hong, Z.; Ruan, J.; Duan, G.; Gao, S.
10.1101/2020.07.22.213926 — bioinformatics — Posted on 2020-07-22
1602 Rescue of SARS-CoV-2 from a single bacterial artificial chromosome
Ye, C.; Park, J.-G.; Oladunni, F.; Platt, R. N.; Anderson, T.; Almazan, F.; de la Torre, J. C.; Martinez-Sobrido, L.
10.1101/2020.07.22.216358 — microbiology — Posted on 2020-07-22
1606 Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
Weisblum, Y.; Schmidt, F.; Zhang, F.; DaSilva, J.; Poston, D.; Lorenzi, J. C. C.; Muecksch, F.; Rutkowska, M.; Hoffmann, H.-H.; Michailidis, E.; Gaebler, C.; Agudelo, M.; Cho, A.; Wang, Z.; Gazumyan, A.; Cipolla, M.; Luchsinger, L.; Hillyer, C. D.; Caskey, M.; Robbiani, D. F.; Rice, C.; Nussenzweig, M. C.; Hatziioannou, T.; Bieniasz, P. D.
10.1101/2020.07.21.214759 — microbiology — Posted on 2020-07-22
1607 Long-reads assembly of the Brassica napus reference genome, Darmor-bzh
Rousseau-Gueutin, M.; Belser, C.; Da Silva, C.; Richard, G.; Istace, B.; Cruaud, C.; Falentin, C.; Boideau, F.; Boutte, J.; Delourme, R.; Deniot, G.; Engelen, S.; Ferreira de Carvalho, J.; Lemainque, A.; Maillet, L.; Morice, J.; Wincker, P.; Denoeud, F.; Chevre, A.-M.; Aury, J.-M.
10.1101/2020.07.22.215749 — genomics — Posted on 2020-07-22
1608 DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan
van Dongen, J.; Hagenbeek, F. A.; Suderman, M.; Roetman, P. J.; Sugden, K.; Chiocchetti, A. G.; Ismail, K.; Mulder, R. H.; Hafferty, J.; Adams, M. J.; Walker, R.; Morris, S.; Lahti, J.; Kupers, L. K.; Escaramis, G.; Alemany, S.; Bonder, M. J.; Meijer, M.; Ip, H. F.; Jansen, R.; Baselmans, B. M. L.; Parmar, P.; Lowry, E.; Streit, F.; Sirignano, L.; Send, T.; Frank, J.; Jylhava, J.; Wang, Y.; Mishra, P. P.; Colins, O. F.; Corcoran, D.; Poulton, R.; Mill, J.; Hannon, E.; Arseneault, L.; Korhonen, T.; Vuoksimaa, E.; Felix, J.; Bakermans-Kranenburg, M.; Campbell, A.; Czamara, D.; Binder, E.; Corpel
10.1101/2020.07.22.215939 — genetics — Posted on 2020-07-22
1612 Spatial patterns in phage-Rhizobium coevolutionary interactions across regions of common bean domestication
Van Cawenberghe, J.; Santamaria, R. I.; Bustos, P.; Juarez, S.; Ducci, M. A.; Fleming, T. F.; Etcheverry, A. V.; Gonzalez, V.
10.1101/2020.07.21.214783 — microbiology — Posted on 2020-07-22
1618 AscA (YecA) is a molecular chaperone involved in Sec-dependent protein translocation in Escherichia coli
Cranford-Smith, T.; Wynne, M.; Carter, C.; Jiang, C.; Jamshad, M.; Milner, M. T.; Djouider, Y.; Hutchinson, E.; Lund, P. A.; Henderson, I. R.; Huber, D.
10.1101/2020.07.21.215244 — molecular biology — Posted on 2020-07-22
1619 The soluble glutathione transferase superfamily: Role of Mu class in Triclabendazole sulphoxide challenge in Fasciola hepatica
Stuart, R. B.; Zwaanswijk, S.; MacKintosh, N. D.; Witikornkul, B.; Prescott, M.; Brophy, P. M.; Morphew, R. M.
10.1101/2020.07.22.213892 — molecular biology — Posted on 2020-07-22
1623 BioContainers Registry: searching for bioinformatics tools, packages and containers
Bai, J.; Bandla, C. R.; Guo, J.; Vera Alvarez, R.; Vizcaino, J. A.; Bai, M.; Moreno Cortez, P. A.; Gruning, B. A.; Sallou, O.; Perez-Riverol, Y.
10.1101/2020.07.21.187609 — bioinformatics — Posted on 2020-07-22
1624 A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease
Alexanian, M.; Przytycki, P. F.; Micheletti, R.; Padmanabhan, A.; Ye, L.; Travers, J. G.; Gonzalez Teran, B.; Duan, Q.; Ranade, S. S.; Felix, F.; Linares-Saldana, R.; Huang, Y.; Andreoletti, G.; Yang, J.; Ivey, K. N.; Jain, R.; McKinsey, T. A.; Rosenfeld, M. G.; Gifford, C.; Pollard, K. S.; Haldar, S. M.; Srivastava, D.
10.1101/2020.07.21.214874 — molecular biology — Posted on 2020-07-22
1626 cDC1 Coordinate Innate and Adaptive Responses in the Omentum required for T cell Priming and Memory
Christian, D. A.; Adams, T. A.; Smith, T. E.; Shallberg, L. A.; Theisen, D. J.; Phan, A. T.; Abraha, M.; Perry, J.; Ruthel, G.; Clark, J. T.; Murphy, K. M.; Kedl, R. M.; Hunter, C. A.
10.1101/2020.07.21.214809 — immunology — Posted on 2020-07-22
1628 Specific interaction of Penetratin with cell surface partners measured with biomembrane force probe
Soule, P.; Illien, F.; Kulifaj, S.; Joliot, A.; Gourier, C.; Sagan, S.; Cribier, S.; Rodriguez, N.
10.1101/2020.07.21.215111 — biophysics — Posted on 2020-07-22
1629 T cells are present in non-diabetic islets and accumulate during aging.
Denroche, H. C.; Miard, S.; Salle-Lefort, S.; Picard, F.; Verchere, C. B.
10.1101/2020.07.21.212977 — physiology — Posted on 2020-07-22
1635 Sex-specific gut microbiota modulation of aversive conditioning and basolateral amygdala dendritic spine density
Geary, C. G.; Wilk, V. C.; Barton, K. L.; Jefferson, P. O.; Binder, T.; Bhutani, V.; Baker, C.; Fernando-Peiris, A. J.; Mousley, A. L.; Rozental, S. F. A.; Thompson, H. M.; Touchon, J. C.; Esteban, D. J.; Bergstrom, H. C.
10.1101/2020.07.21.213116 — neuroscience — Posted on 2020-07-22
1636 dN/dS dynamics quantify tumour immunogenicity and predict response to immunotherapy
Zapata, L.; Caravagna, G.; Williams, M.; Lakatos, E.; Abdul-Jabbar, K.; Werner, B.; Graham, T. A.; Sottoriva, A.
10.1101/2020.07.21.215038 — genomics — Posted on 2020-07-22
1638 Genomic adaptations to an endolithic lifestyle in the coral-associated alga Ostreobium
Iha, C.; Varela, J. A.; Avila, V.; Jackson, C. J.; Bogaert, K. A.; Chen, Y.; Judd, L. M.; Wick, R. R.; Holt, K. E.; Pasella, M. M.; Ricci, F.; Repetti, S. I.; Medina, M.; Marcelino, V. R.; Chan, C. X.; Verbruggen, H.
10.1101/2020.07.21.211367 — genomics — Posted on 2020-07-22
1639 Beyond orphaned infants: novel effects of maternal death in wild primates
Zipple, M. N.; Altmann, J.; Campos, F. A.; Cords, M.; Fedigan, L. M.; Lawler, R. R.; Lonsdorf, E. V.; Perry, S.; Pusey, A. E.; Stoinski, T. S.; Strier, K.; Alberts, S. C.
10.1101/2020.07.22.212605 — evolutionary biology — Posted on 2020-07-22
1641 Ranking the direct threats to biodiversity in sub-Saharan Africa
Leisher, C.; Robinson, N.; Brown, M.; Kujirakwinja, D.; Castro Schmitz, M.; Wieland, M.; Wilkie, D.
10.1101/2020.07.22.175513 — ecology — Posted on 2020-07-22
1644 ABCB-mediated auxin transport in outer root tissues regulates lateral root spacing in Arabidopsis
CHEN, J.; Hu, Y.; Hao, P.; Zhang, Y.; Roth, O.; Njo, M.; Sterck, L.; Hu, Y.; Zhao, Y.; Geisler, M.; Shani, E.; Beeckman, T.; Vanneste, S.
10.1101/2020.07.22.206300 — plant biology — Posted on 2020-07-22
1647 T cell subset-selective IL2RA enhancers shape autoimmune diabetes risk
Simeonov, D. R.; Wong, H. S.; Cortez, J. T.; Young, A.; Li, Z.; Nguyen, V.; Park, K.; Umhoefer, J.; Indart, A. C.; Woo, J. M.; Anderson, M. S.; Germain, R. N.; Marson, A.
10.1101/2020.07.22.216564 — immunology — Posted on 2020-07-22
1648 A pan-cancer atlas of somatic mutations in miRNA biogenesis genes
Galka-Marciniak, P.; Urbanek-Trzeciak, M. O.; Nawrocka, P. M.; Kozlowski, P.
10.1101/2020.07.22.216499 — genomics — Posted on 2020-07-22
1651 In Situ Unzipping of Long, High Molecular Weight DNA in Solid State Nanopores
Losakul, R.; Tobar, D. E.; Pimenov, A.; Gutierrez, A.; Schipper, R.; Jehle, W. A.; Postma, H. W. C.
10.1101/2020.07.21.214445 — biophysics — Posted on 2020-07-22
1653 Assessment of current taxonomic assignment strategies for metabarcoding eukaryotes
Hleap, J. S.; Littlefair, J. E.; Steinke, D.; Hebert, P. D. N.; Cristescu, M. E.
10.1101/2020.07.21.214270 — bioinformatics — Posted on 2020-07-22
1654 DreamAI: algorithm for the imputation of proteomics data
ma, w.; Kim, S.; Chowdhury, S.; li, z.; YANG, M.; Yoo, S.; Petralia, F.; Jacobsen, J.; Li, J. J.; Ge, X.; Li, K.; Yu, T.; Edwards, N. J.; Payne, S.; Boutros, P. C.; Rodriguez, H.; Stolovitzky, G. A.; Kang, J.; Fenyo, D.; Saez, J.; Wang, P.
10.1101/2020.07.21.214205 — bioinformatics — Posted on 2020-07-22
1655 Inference and analysis of cell-cell communication using CellChat
Jin, S.; Guerrero-Juarez, C. F.; Zhang, L.; Chang, I.; Myung, P.; Plikus, M. V.; Nie, Q.
10.1101/2020.07.21.214387 — bioinformatics — Posted on 2020-07-22
1656 Parallelized manipulation of adherent living cells by magnetic nanoparticles-mediated forces
Bongaerts, M.; Aizel, K.; Secret, E.; Jan, A.; Nahar, T.; Raudzus, F.; Neumann, S.; Telling, N.; Heumann, R.; Siaugue, J.-M.; Menager, C.; Fresnais, J.; Villard, C.; El Haj, A.; Piehler, J.; Gates, M.; Coppey, M.
10.1101/2020.07.21.212373 — bioengineering — Posted on 2020-07-22
1659 A primed immune transcriptional program is activated in oligodendroglia in multiple sclerosis
Meijer, M.; Agirre, E.; Kabbe, M.; van Tuijn, C.; Heskol, A.; Falcao, A. M.; Corces, M. R.; Montine, T.; Chen, X.; Chang, H. Y.; Castelo-Branco, G.
10.1101/2020.07.21.213876 — neuroscience — Posted on 2020-07-22
1664 Evaluating tank acclimation and trial length for shuttle box temperature preference assays
Harman, A. A.; Fuzzen, M.; Stoa, L.; Boreham, D.; Manzon, R.; Somers, C. M.; Wilson, J. Y.
10.1101/2020.07.21.214080 — physiology — Posted on 2020-07-22
1665 Comparison of long read sequencing technologies in resolving bacteria and fly genomes
Tvedte, E. S.; Gasser, M.; Sparklin, B. C.; Michalski, J.; Zhao, X.; Bromley, R.; Tallon, L. J.; Sadzewicz, L.; Rasko, D. A.; Dunning Hotopp, J. C.
10.1101/2020.07.21.213975 — genomics — Posted on 2020-07-22
1666 New mechanisms of radioiodide uptake revealed via a novel high throughput drug screening approach in thyroid cancer
Read, M. L.; Brookes, K.; Thornton, C. E. M.; Fletcher, A.; Alshahrani, M.; Khan, R.; Nieto, H. R.; Borges de Souza, P.; Webster, J. R. M.; Alderwick, L. J.; Boelaert, K.; Smith, V. E.; McCabe, C. J.
10.1101/2020.07.21.213967 — cancer biology — Posted on 2020-07-22
1667 A novel role of MNT as a negative regulator of REL and the NF-κB pathway
Liano-Pons, J.; Lafita-Navarro, M. C.; Colomer, C.; Garcia-Gaipo, L.; Rodriguez, J.; von Kriegsheim, A.; Hurlin, P.; Delgado, M. D.; Bigas, A.; Espinosa, L.; Leon, J.
10.1101/2020.07.21.210989 — cancer biology — Posted on 2020-07-22
1668 Neural Stem Cells Secreting Bispecific T Cell Engager to Induce Selective Anti-Glioma Activity
Pituch, K. C.; Zannikou, M.; Ilut, L.; Xiao, T.; Chastkofsky, M.; Sukhanova, M.; Bertolino, N.; Procissi, D.; Amidei, C.; Horbinski, C.; Aboody, K. S.; James, C. D.; Lesniak, M. S.; Balyasnikova, I. V.
10.1101/2020.07.21.188441 — immunology — Posted on 2020-07-22
1671 The architecture of the centriole cartwheel-containing region revealed by cryo-electron tomography
Klena, N.; Le Guennec, M.; Tassin, A.-M.; van den Hoek, H.; Erdmann, P. S.; Schaffer, M.; Geimer, S.; Aeschlimann, G.; Kovacik, L.; Goldie, K. N.; Stahlberg, H.; Engel, B. D.; Hamel, V.; Guichard, P.
10.1101/2020.07.21.068882 — cell biology — Posted on 2020-07-22
1676 Neuronal SKN-1B Modulates Nutritional Signalling Pathways and Mitochondrial Networks to Control Satiety
Tataridas-Pallas, N.; Thompson, M. A.; Howard, A.; Brown, I.; Ezcurra, M.; Wu, Z.; Kuerten, T.; Goncalves Silva, I.; Blackwell, T. K.; Tullet, J. M. A.
10.1101/2020.07.21.213504 — animal behavior and cognition — Posted on 2020-07-22
1679 Molecular analyses reveal consistent food web structure with elevation in rainforest Drosophila - parasitoid communities
Jeffs, C. T.; Terry, J. C. D.; Higgie, M.; Jandova, A.; Konvickova, H.; Brown, J. J.; Lue, C.-H.; Schiffer, M.; O'Brien, E. K.; Bridle, J.; Hrcek, J.; Lewis, O. T.
10.1101/2020.07.21.213678 — ecology — Posted on 2020-07-22
1680 Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA transcripts is driven by intron retention: implications for RNA-directed therapies
Dumbovic, G.; Braunschweig, U.; K. Langner, H. K.; Jastrzebska, K.; Smallegan, M.; Blencowe, B.; Cech, T. R.; Caruthers, M. H.; Rinn, J. L.
10.1101/2020.07.21.212514 — cell biology — Posted on 2020-07-22
1682 Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study
Nolan, A. L.; Petersen, C.; Iacono, D.; Mac Donald, C. L.; Mukherjee, P.; van der Kouwe, A.; Jain, S.; Stevens, A.; Diamond, B. R.; Wang, R.; Markowitz, A. J.; Fischl, B.; Perl, D. P.; Manley, G. T.; Keene, C. D.; Diaz-Arrastia, R.; Edlow, B. L.; the TRACK-TBI Investigators,
10.1101/2020.07.20.209668 — neuroscience — Posted on 2020-07-22
1683 Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans
Holzer, B.; Rijal, P.; McNee, A.; Paudyal, B.; Clark, B.; Manjegowda, T.; Salguero, F. J.; Bessell, E.; Schwartz, J. C.; Moffat, K.; Pedrera, M.; Graham, S. P.; Placido, M. B.-D.; La Ragione, R. M.; Mwangi, W.; Beverley, P.; McCauley, J. W.; Daniels, R. S.; Hammond, J.; Townsend, A. R.; Tchilian, E.
10.1101/2020.07.21.213470 — immunology — Posted on 2020-07-22
1686 Characterization of Plasmodium falciparum NEDD8 and identification of cullins as its substrates
Bhattacharjee, M.; Adhikari, N.; Sudhakar, R.; Rizvi, Z.; Das, D.; Palanimurugan, R.; Sijwali, P. S.
10.1101/2020.07.21.213488 — biochemistry — Posted on 2020-07-22
1687 Production of the Short Chain Fatty Acid, Acetic Acid/Acetate from Ethanol Metabolism Activates NMDAR
Chapp, A.; Huber, M.; Driscoll, K.; Behnke, J.; Larson, R.; Schum, S.; Shan, Z.; Zhang, L.; Chen, Q.
10.1101/2020.07.20.212597 — physiology — Posted on 2020-07-22
1688 Neural correlates of the shamanic state of consciousness
Huels, E. R.; Kim, H.; Lee, U.; Bel-Bahar, T.; Colmenero, A.; Nelson, A.; Blain-Moraes, S.; Mashour, G. A.; Harris, R. E.
10.1101/2020.07.20.212522 — neuroscience — Posted on 2020-07-22
1689 HIV coinfection is associated with low fitness rpoB variants in rifampicin-resistant Mycobacterium tuberculosis
Loiseau, C.; Brites, D.; Reinhard, M.; Zuercher, K.; Borrell, S.; Ballif, M.; Fenner, L.; Cox, H.; Rutaihwa, L. K.; Wilkinson, R. J.; Yotebieng, M.; Carter, E. J.; Abimiku, A.; Marcy, O.; Gotuzzo, E.; Avihingsanon, A.; Zetola, N.; Doulla, B.; Boettger, E. C.; Egger, M.; Gagneux, S.
10.1101/2020.07.20.208835 — evolutionary biology — Posted on 2020-07-22
1693 Discordant transcriptional signatures of mitochondrial genes in Parkinson's disease human myeloid cells
Navarro, E.; Udine, E.; de Paiva Lopes, K.; Parks, M.; Riboldi, G.; Schilder, B. M.; Humphrey, J.; Snijders, G. J. L.; Vialle, R. A.; Zhuang, M.; Sikder, T.; Argyrou, C.; Allan, A.; Chao, M.; Farrell, K.; Henderson, B.; Simon, S.; Raymond, D.; Elango, S.; Ortega, R. A.; Shanker, V.; Swan, M.; Zhu, C.; Ramdhani, R.; Walker, R. H.; Tse, W.; Sano, M.; Pereira, A. C.; Ahfeldt, T.; Goate, A. M.; Bressman, S.; Crary, J. F.; de Witte, L.; Frucht, S.; Saunders-Pullman, R.; Raj, T.
10.1101/2020.07.20.212407 — neuroscience — Posted on 2020-07-22
1694 Comparative analysis of single-cell RNA Sequencing Platforms and Methods
Ashton, J. M.; Rehrauer, H.; Myers, J.; Myers, J.; Zanche, M.; Balys, M.; Foox, J.; Mason, C. E.; Steen, R.; Kuentzel, M.; Aquino, C.; Garcia-Reyero, N.; Chittur, S. V.
10.1101/2020.07.20.212100 — genomics — Posted on 2020-07-22
1695 Global patterns of aegyptism without arbovirus
Olson, M. F.; Juarez, J. G.; Kraemer, M. U. G. F.; Messina, J.; Hamer, G. L.
10.1101/2020.07.20.212209 — ecology — Posted on 2020-07-22
1697 Berberine alleviates adiposity and cardiac dysfunction in offspring exposed to gestational diabetes mellitus
Cole, L. K.; Zhang, M.; Chen, L.; Sparagna, G. C.; Vandel, M.; Xiang, B.; Dolinsky, V. W.; Hatch, G. M.
10.1101/2020.07.20.209395 — physiology — Posted on 2020-07-22
1698 Discovery of A New Class of Integrin Antibodies for Fibrosis
Zhang, J.; Wang, T.; Saigal, A.; Johnson, J.; Morrisson, J.; Tabrizifard, S.; Hollingsworth, S. A.; Eddins, M. J.; Mao, W.; O'Neill, K.; Garcia-Calvo, M.; Carballo-Jane, E.; Liu, D.; Ham, T.; Zhou, Q.; Dong, W.; Meng, H.-W.; Hicks, J.; Cai, T.-Q.; Akiyama, T. E.; Pinto, S.; Cheng, A. C.; Greshock, T. J.; Marquis, J. C.; Ren, Z.; Talukdar, S.; Shaheen, H. H.; Handa, M.
10.1101/2020.07.20.207555 — pharmacology and toxicology — Posted on 2020-07-22
1700 Oviposition of the mosquito Aedes aegypti in forest and domestic habitats in Africa
Xia, S.; Dweck, H. K. M.; Lutomiah, J.; Sang, R.; McBride, C. S.; Rose, N. H.; Ayala, D.; Powell, J. R.
10.1101/2020.07.08.192187 — evolutionary biology — Posted on 2020-07-22
1704 Human Prefoldin Modulates Co-transcriptional Pre-mRNA Splicing
Payan-Bravo, L.; Penate, X.; Cases, I.; Pareja-Sanchez, Y.; Fontalva, S.; Odriozola, Y.; Lara, E.; Jimeno-Gonzalez, S.; Sune, C.; Reyes, J. C.; Chavez, S.
10.1101/2020.06.14.150466 — molecular biology — Posted on 2020-07-22
1706 ALG-2 interacting protein-X (Alix) is required for activity-dependent bulk endocytosis at brain synapses
Laporte, M. H.; Chi, K. I.; Rolland, M.; Caudal, L. C.; Martinez-Hernandez, J.; Martineau, M.; Chatellard, C.; Denarier, E.; Mercier, V.; Lemaitre, F.; Blot, B.; Moutaux, E.; Cazorla, M.; Buisson, A.; Perrais, D.; Fraboulet, S.; Lante, F.; Kirchhoff, F.; Hemming, F. J.; Sadoul, R.
10.1101/2020.07.20.211854 — neuroscience — Posted on 2020-07-22
1707 Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase
Kouba, T.; Koval, T.; Sudzinova, P.; Pospisil, J.; Brezovska, B.; Hnilicova, J.; Sanderova, H.; Janouskova, M.; Sikova, M.; Halada, P.; Sykora, M.; Barvik, I.; Novacek, J.; Trundova, M.; Duskova, J.; Skalova, T.; Chon, U.; Murakami, K.; Dohnalek, J.; Krasny, L.
10.1101/2020.07.20.211821 — molecular biology — Posted on 2020-07-22
1708 A phosphoproteomic approach reveals that PKD3 controls phenylalanine and tyrosine metabolism
Mayer, A. E.; Loza Valdes, A.; Schmitz, W.; Trujillo Viera, J.; Leitges, M.; Schlosser, A.; Sumara, G.
10.1101/2020.07.20.211474 — biochemistry — Posted on 2020-07-22
1709 Endothelial expression of human APP leads to cerebral amyloid angiopathy in mice
Tachida, Y.; Miura, S.; Imamaki, R.; Ogasawara, N.; Takuwa, H.; Sahara, N.; Shindo, A.; Matsuba, Y.; Saito, T.; Taniguchi, N.; Kawaguchi, Y.; Tomimoto, H.; Saido, T.; Kitazume, S.
10.1101/2020.07.22.215418 — neuroscience — Posted on 2020-07-22
1711 Local translation in synaptic mitochondria influences synaptic transmission
Yousefi, R.; Fornasiero, E. F.; Cyganek, L.; Jakobs, S.; Rizzoli, S. O.; Rehling, P.; Pacheu Grau, D.
10.1101/2020.07.22.215194 — biochemistry — Posted on 2020-07-22
1712 Chemogenetic silencing of hippocampus and amygdala reveals a double dissociation in periadolescent obesogenic diet-induced memory alterations
Naneix, F.; Bakoyiannis, I.; Santoyo-Zedillo, M.; Bosch-Bouju, C.; Pacheco-Lopez, G.; Coutureau, E.; Ferreira, G.
10.1101/2020.07.20.212258 — neuroscience — Posted on 2020-07-22
1717 Voluntary wheel running improves outcomes in an early life stress-induced model of urologic chronic pelvic pain syndrome in male mice
Fuentes, I. M.; Jones, B. M.; Brake, A. D.; Pierce, A. N.; Eller, O. C.; Supple, R. M.; Wright, D. E.; Christianson, J. A.
10.1101/2020.07.20.212480 — neuroscience — Posted on 2020-07-22
1718 An online headphone screening test based on dichotic pitch
Milne, A. E.; Bianco, R.; Poole, K. C.; Zhao, S.; Billig, A. J.; Chait, M. E.
10.1101/2020.07.21.214395 — neuroscience — Posted on 2020-07-22
1719 Raman imaging analysis of microvesicular and macrovesicular lipid droplets in non-alcoholic fatty liver disease
Minamikawa, T.; Ichimura-Shimizu, M.; Takanari, H.; Morimoto, Y.; Shiomi, R.; Tanioka, H.; Hase, E.; Yasui, T.; Tsuneyama, K.
10.1101/2020.07.20.212803 — pathology — Posted on 2020-07-21
1723 Proteomic Differences in the Hippocampus and Cortex of Epilepsy Brain Tissue
Pires, G.; Leitner, D.; Drummond, E. E.; Kanshin, E.; Nayak, S.; Askenazi, M.; Faustin, A.; Friedman, D.; Debure, L.; Ueberheide, B.; Wisniewski, T.; Devinsky, O.
10.1101/2020.07.21.209163 — neuroscience — Posted on 2020-07-21
1726 Kv1.2 contributes to pattern separation by regulating the hippocampal CA3 neuronal ensemble size
Eom, K.; Lee, H. R.; Hyun, J. H.; Ryu, H.-H.; Lee, Y.-S.; Lee, I.; Ho, W.-K.; Lee, S.-H.
10.1101/2020.07.21.213538 — neuroscience — Posted on 2020-07-21
1727 Rostro-caudal specificity of corticospinal tract projections in mice
Steward, O.; Yee, K. M.; Metcalfe, M.; Luo, J.; Willenberg, R.; Acevedo, R.; Martin-Thompson, J.; Gandhi, S.
10.1101/2020.07.21.214908 — neuroscience — Posted on 2020-07-21
1729 Motor and Sensory Cortical Processing of Neural Oscillatory Activities revealed by Human Swallowing using Intracranial Electrodes
Hashimoto, H.; Takahashi, K.; Kameda, S.; Yoshida, F.; Maezawa, H.; Oshino, S.; Tani, N.; Khoo, H. M.; Yanagisawa, T.; Yoshimine, T.; Kishima, H.; Hirata, M.
10.1101/2020.07.21.213868 — neuroscience — Posted on 2020-07-21
1732 INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly
Mascibroda, L. G.; Shboul, M.; Elrod, N. D.; Colleaux, L.; Hamamy, H.; Huang, K.-L.; Peart, N. J.; Singh, M. K.; Lee, H.; Merriman, B.; Jodoin, J. N.; Lee, L. A.; Al-Rawashdeh, B.; Ababneh, O.; El-Khateeb, M.; Fathalla, R.; Escande-Beillard, N.; Nelson, S. F.; Wu, Y.; Tong, L.; Kenney, L. J.; Russell, W. K.; Amiel, J.; Reversade, B.; Wagner, E. J.
10.1101/2020.07.20.209130 — biochemistry — Posted on 2020-07-21
1735 Effects of early life stress on bone homeostasis in mice and humans
Wuertz-Kozak, K.; Roszkowski, M.; Cambria, E.; Block, A.; Kuhn, G. A.; Abele, T.; Hitzl, W.; Driesslein, D.; Mueller, R.; Rapp, M.; Mansuy, I. M.; Peters, E. M. J.; Wippert, P. M.
10.1101/2020.07.21.214122 — physiology — Posted on 2020-07-21
1739 High-Fiber Diet Restores Maternal Obesity-Induced Cognitive and Social Behavioral Deficits in Offspring via Regulating Gut Microbiota-Metabolites-Brain Axis
Liu, X.; Li, X.; Xia, B.; Jin, X.; Zeng, Z.; Yan, S.; Li, L.; Yuan, S.; Zhao, S.; Dai, X.; Yin, F.; Cadenas, E.; Liu, R. H.; Zhao, B.; Hou, M.; Liu, Z.; Liu, X.
10.1101/2020.07.16.206714 — neuroscience — Posted on 2020-07-21
1746 Elucidating essential genes in plant-associated Pseudomonas protegens Pf-5 using transposon insertion sequencing
Fabian, B. K.; Foster, C.; Asher, A. J.; Elbourne, L. D.; Cain, A. K.; Hassan, K. A.; Tetu, S. G.; Paulsen, I. T.
10.1101/2020.07.16.205906 — genomics — Posted on 2020-07-21
1749 Form, function, and divergence of a generic fin shape in small cetaceans
Pavlov, V.; Vincent, C.; Mikkelsen, B.; Lebeau, J.; Ridoux, V.; Siebert, U.
10.1101/2020.07.21.214734 — evolutionary biology — Posted on 2020-07-21
1751 Genome-wide binding analysis of 195 DNA Binding Proteins reveals "reservoir" promoters and human specific SVA-repeat family regulation
Shehata, S.; Spradlin, S.; Swearingen, A.; Wheeler, G.; Das, A.; Corbet, G.; Nebenfuehr, B.; Ahrens, D.; Tauber, D.; Lennon, S.; Choi, K.; Huynh, T.; Weiser, T.; Schneider, K.; Bradshaw, M.; Lai, M.; Baskin, J.; Read, T.; Demasi, J.; Hynes-Grace, M.; Timmons, D.; Smallegan, M.; Rinn, J. L.
10.1101/2020.07.21.213603 — genomics — Posted on 2020-07-21
1753 Inhibition of CRISPR-Cas12a DNA Targeting by Nucleosomes and Chromatin
Strohkendl, I.; Saifuddin, F. A.; Gibson, B. A.; Rosen, M. K.; Russell, R.; Finkelstein, I. J.
10.1101/2020.07.18.210054 — biochemistry — Posted on 2020-07-21
1755 What's the temperature in tropical caves?
Mejia-Ortiz, L.; Christman, M. C.; Pipan, T.; Culver, D. C.
10.1101/2020.07.21.213579 — ecology — Posted on 2020-07-21
1756 Stochastic Analysis Demonstrates the Dual Role of Hfq in Chaperoning E. coli Sugar Shock Response
Bianchi, D. M.; Brier, T. A.; Poddar, A.; Azam, M. S.; Vanderpool, C. K.; Ha, T.; Luthey-Schulten, Z.
10.1101/2020.06.30.178566 — biophysics — Posted on 2020-07-21
1757 Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles
Hershewe, J. M.; Warfel, K. F.; Iyer, S. M.; Peruzzi, J. A.; Sullivan, C. J.; Roth, E. W.; DeLisa, M. P.; Kamat, N. P.; Jewett, M. C.
10.1101/2020.07.19.211201 — synthetic biology — Posted on 2020-07-21
1758 A single-cell transcriptome atlas of the aging human and macaque retina
Yi, W.; Lu, Y.; Zhong, S.; Zhang, M.; Sun, L.; Dong, H.; Wang, M.; Wei, M.; Xie, H.; Qu, H.; Peng, R.; Hong, J.; Yao, Z.; Tong, Y.; Wang, W.; Ma, Q.; Liu, Z.; Ma, Y.; Li, S.; Yin, C.; Liu, J.; Ma, C.; Wang, X.; Wu, Q.; Xue, T.
10.1101/2020.07.17.207977 — neuroscience — Posted on 2020-07-21
1759 A biaryl-linked tripeptide from Planomonospora leads to widespread class of minimal RiPP gene clusters
Zdouc, M. M.; Alanjary, M. M.; Zarazua, G. S.; Maffioli, S. I.; Crüsemann, M.; Medema, M. H.; Donadio, S.; Sosio, M.
10.1101/2020.07.21.214643 — microbiology — Posted on 2020-07-21
1760 Targeted Genome Editing of Bacteria Within Microbial Communities
Rubin, B. E.; Diamond, S.; Cress, B. F.; Crits-Christoph, A.; He, C.; Xu, M.; Zhou, Z.; Smock, D. C.; Tang, K.; Owens, T. K.; Krishnappa, N.; Sachdeva, R.; Deutschbauer, A. M.; Banfield, J. F.; Doudna, J. A.
10.1101/2020.07.17.209189 — microbiology — Posted on 2020-07-21
1761 Long-read genome sequencing for the diagnosis of neurodevelopmental disorders
Hiatt, S. M.; Lawlor, J. M.; Handley, L. H.; Ramaker, R. C.; Rogers, B. B.; Partridge, E. C.; Boston, L. B.; Williams, M.; Jenkins, J.; Gray, D. E.; Holt, J. M.; Bowling, K. M.; Bebin, E. M.; Grimwood, J.; Schmutz, J.; Cooper, G. M.
10.1101/2020.07.02.185447 — genomics — Posted on 2020-07-21
1762 Donor-derived mitochondrial DNA variant peptides elicit allo-specific immune response in transplant patients
Marishta, A.; Yang, Y.; Hu, X.; Jang, M. K.; Cuttin, K.; Jackson, A. M.; Luikart, H.; Deuse, T.; Khush, K. K.; Schrepfer, S.; Agbor-Enoh, S.; Valantine, H.
10.1101/2020.06.04.134965 — genomics — Posted on 2020-07-21
1766 Time-resolved comparative molecular evolution of oxygenic photosynthesis
Oliver, T.; Sanchez-Baracaldo, P.; Larkum, A. W.; Rutherford, A. W.; Cardona, T.
10.1101/2020.02.28.969766 — evolutionary biology — Posted on 2020-07-21
1769 Ferroportin 3 is a dual-targeted mitochondrial/chloroplast iron exporter necessary for iron homeostasis in Arabidopsis
Kim, L. J.; Tsuyuki, K. M.; Hu, F.; Park, E. Y.; Zhang, J.; Gallegoe Iraheta, J.; Chia, J.-C.; Huang, R.; Tucker, A. E.; Clyne, M.; Castellano, C.; Kim, A.; Chung, D. D.; DaVeiga, C. T.; Parsons, E. M.; Vatamaniuk, O. K.; Jeong, J.
10.1101/2020.07.15.203646 — plant biology — Posted on 2020-07-21
1770 A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death and modulation of growth and synaptic assembly
Iqbal, F.; Pehar, M.; Thompson, A.; Azeem, U.; Jahanbakhsh, K.; Jimenez-Tellez, N.; Sabouny, R.; Batool, S.; Ibrahim, A.; Chow, J.; Machiraju, P.; Shutt, T.; Yusuf, K.; Shearer, J.; Rice, T.; Syed, N.
10.1101/2020.06.18.159889 — neuroscience — Posted on 2020-07-21
1772 Ivermectin inhibits extracellular vesicle secretion from parasitic nematodes
Loghry, H. J.; Yuan, W.; Zamanian, M.; Wheeler, N. J.; Day, T. A.; Kimber, M. J.
10.1101/2020.07.20.212290 — molecular biology — Posted on 2020-07-21
1776 Fibroblast fusion to the muscle fiber regulates myotendinous junction formation
Yaseen-Badarneh, W.; Kraft-Sheleg, O.; Zaffryar-Eilot, S.; Melamed, S.; Sun, C.; Millay, D.; Hasson, P.
10.1101/2020.07.20.213199 — developmental biology — Posted on 2020-07-21
1777 Wnt-and Glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division
Junyent, S.; Reeves, J. C.; Szczerkowski, J. L. A.; Garcin, C. L.; Trieu, T.-J.; Wilson, M.; Habib, S.
10.1101/2020.06.16.154609 — cell biology — Posted on 2020-07-21
1778 Mitophagy protects beta cells from inflammatory damage in diabetes
Sidarala, V.; Pearson, G. L.; Parekh, V. S.; Thompson, B.; Christen, L.; Gingerich, M. A.; Zhu, J.; Stromer, T.; Ren, J.; Reck, E.; Chai, B.; Corbett, J. A.; Mandrup-Poulsen, T.; Satin, L. S.; Soleimanpour, S. A.
10.1101/2020.06.07.138917 — cell biology — Posted on 2020-07-21
1780 The PIF1-MIR408-Plantacyanin Repression Cascade Regulates Light Dependent Seed Germination
Jiang, A.; Guo, Z.; Pan, J.; Zhuang, Y.; Zuo, D.; Hao, C.; Gao, Z.; Xin, P.; Chu, J.; Zhong, S.; Li, L.
10.1101/2020.07.20.212340 — plant biology — Posted on 2020-07-21
1781 CRISPR-Cas9-mediated editing of myb28 impairs glucoraphanin accumulation of Brassica oleracea in the field
Neequaye, M.; Stavnstrup, S.; Lawrenson, T.; Hundleby, P.; Troncoso-Rey, P.; Saha, S.; Harwood, W.; Traka, M.; Mithen, R.; Ostergaard, L.
10.1101/2020.07.16.206813 — plant biology — Posted on 2020-07-21
1782 α-Synuclein strains that cause distinct pathologies differentially inhibit proteasome
Suzuki, G.; Imura, S.; Hosokawa, M.; Katsumata, R.; Nonaka, T.; Hisanaga, S.-I.; Saeki, Y.; Hasegawa, M.
10.1101/2020.03.19.999086 — neuroscience — Posted on 2020-07-21
1784 Anxiety and the neurobiology of temporally uncertain threat anticipation
Hur, J.; Smith, J. F.; DeYoung, K. A.; Anderson, A. S.; Kuang, J.; Kim, H. C.; Tillman, R. M.; Kuhn, M.; Fox, A. S.; Shackman, A. J.
10.1101/2020.02.25.964734 — neuroscience — Posted on 2020-07-21
1785 Linking cerebellar functional gradients to transdiagnostic behavioral dimensions of psychopathology
Dong, D.; Guell, X.; Genon, S.; Wang, Y.; Chen, J.; Eickhoff, S. B.; Luo, C.; Yao, D.
10.1101/2020.06.15.153254 — neuroscience — Posted on 2020-07-21
1788 Austropuccinia psidii, causing myrtle rust, has a gigabase-sized genome shaped by transposable elements
Tobias, P. A.; Schwessinger, B.; Deng, C. H.; Wu, C.; Dong, C. M.; Sperschneider, J.; Jones, A.; Lou, Z.; Zhang, P.; Sandhu, K.; Smith, G. R.; Tibbits, J.; Chagne, D.; Park, R.
10.1101/2020.03.18.996108 — genomics — Posted on 2020-07-21
1790 A series of Orai1 gating checkpoints in transmembrane and cytosolic regions requires clearance for CRAC channel opening
Tiffner, A.; Schober, R.; Hoeglinger, C.; Bonhenry, D.; Pandey, S.; Lunz, V.; Sallinger, m.; Frischauf, I.; Fahrner, M.; Lindinger, S.; Maltan, L.; Berlansky, S.; Stadlbauer, M.; Schindl, R.; Ettrich, R.; Romanin, C.; Derler, I.
10.1101/2020.07.16.207183 — biophysics — Posted on 2020-07-21
1791 Differential tissue stiffness of body column facilitates locomotion of Hydra on solid substrates
Naik, S.; Unni, M. K.; Sinha, D.; Rajput, S. S.; Puli, C. R.; Kartvelishvily, E.; Solomonov, I.; Sagi, I.; Chatterji, A.; Patil, S.; Galande, S.
10.1101/2020.02.29.971044 — biophysics — Posted on 2020-07-21
1793 Modeling alcoholic liver disease in a human Liver-Chip
Nawroth, J. C.; Petropolis, D. B.; Manatakis, D. V.; Maulana, T. I.; Burchett, G.; Schluender, K.; Witt, A.; Shukla, A.; Hamilton, G.; Seki, E.; Lu, S.; Karalis, K.
10.1101/2020.07.14.203166 — bioengineering — Posted on 2020-07-21
1797 Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice
Botezelli, J. D.; Overby, P.; Lindo, L.; Wang, S. D.; Haida, O.; Lim, G. E.; Templeman, N. M.; Pauli, J. R.; Johnson, J. D.
10.1101/2020.03.31.018432 — physiology — Posted on 2020-07-21
1798 Structural and functional brain parameters related to cognitive performance across development: Replication and extension of the parieto-frontal integration theory in a single sample.
Gur, R. C.; Butler, E. R.; Moore, T. M.; Rosen, A. F. G.; Ruparel, K.; Satterthwaite, T. D.; Roalf, D. R.; Gennatas, E. D.; Bilker, W. B.; Shinohara, R. T.; Port, A.; Elliott, M. A.; Verma, R.; Davatzikos, C.; Wolf, D. H.; Detre, J. A.; Gur, R. E.
10.1101/659193 — neuroscience — Posted on 2020-07-21
1808 A sparse observation model to quantify species interactions in time and space
Ait Kaci Azzou, S.; Singer, L.; Aebischer, T.; Wolf, B.; Wegmann, D.
10.1101/815027 — ecology — Posted on 2020-07-21
1810 ProtTrans: Towards Cracking the Language of Life's Code Through Self-Supervised Deep Learning and High Performance Computing
Elnaggar, A.; Heinzinger, M.; Dallago, C.; Rehawi, G.; Wang, Y.; Jones, L.; Gibbs, T.; Feher, T.; Angerer, C.; Steinegger, M.; BHOWMIK, D.; Rost, B.
10.1101/2020.07.12.199554 — bioinformatics — Posted on 2020-07-21
1811 FastPG: Fast clustering of millions of single cells
Bodenheimer, T.; Halappanavar, M.; Jefferys, S.; Gibson, R.; Liu, S.; Mucha, P. J.; Stanley, N.; Parker, J. S.; Selitsky, S. R.
10.1101/2020.06.19.159749 — bioinformatics — Posted on 2020-07-21
1812 ampir: an R package for fast genome-wide prediction of antimicrobial peptides
Fingerhut, L. C.; Miller, D. J.; Strugnell, J. M.; Daly, N. L.; Cooke, I. R.
10.1101/2020.05.07.082412 — bioinformatics — Posted on 2020-07-21
1813 A mechanistic model improves off-target predictions and reveals the physical basis of SpCas9 fidelity
Eslami-Mossallam, B.; Klein, M.; Smagt, C. v. d.; Sanden, K. v. d.; Jones, S. K.; Hawkins, J. A.; Finkelstein, I. J.; Depken, M.
10.1101/2020.05.21.108613 — biophysics — Posted on 2020-07-21
1815 Network Reconstruction from Perturbation Time Course Data
Smith, G. R.; Sarmah, D.; Bouhaddou, M.; Stern, A. D.; Erskine, J.; Birtwistle, M.
10.1101/341008 — systems biology — Posted on 2020-07-21
1820 Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes
Ruiz, L.; Kaczmarska, Z.; Gomes, T.; Martin-Malpartida, P.; Aragon, E.; Torner, C.; Freier, R.; Baginski, B.; de Martin Garrido, N.; Marquez, J. A.; Cordeiro, T. N.; Pluta, R.; Macias, M. J.
10.1101/833319 — molecular biology — Posted on 2020-07-21
1821 Synchronized beta cell response to glucose is lost concomitant with loss of islet architecture in Robo deficient islets of Langerhans in vivo
Adams, M. T.; Reissaus, C. A.; Dwulet, J. M.; Jin, E.; Szulczewski, J. M.; Lyman, M. R.; Sdao, S. M.; Nimkulrat, S. D.; Ponik, S. M.; Merrins, M. J.; Benninger, R. K. P.; Mirmira, R. G.; Linnemann, A. K.; Blum, B.
10.1101/2019.12.11.873471 — developmental biology — Posted on 2020-07-21
1824 Precise and programmable C:G to G:C base editing in genomic DNA
Chen, L.; Park, J. E.; Paa, P.; Rajakumar, P. D.; Chew, Y. T.; Manivannan, S. N.; Chew, W. L.
10.1101/2020.07.21.213827 — synthetic biology — Posted on 2020-07-21
1825 FERONIA regulates FLS2 plasma membrane nanoscale dynamics to modulate plant immune signaling
zipfel, c.; Gronnier, J.; Franck, C. M.; Stegmann, M.; DeFalco, T.; Abarca, A.; Duenser, K.; Lin, W.; Yang, Z.; Kleine-Vehn, J.; Ringli, C.
10.1101/2020.07.20.212233 — plant biology — Posted on 2020-07-21
1828 "The good, the bad and the double-sword" effects of exposure to MPs and their organic additives on N2-fixing bacteria
Fernandez-Juarez, V.; Lopez-Alforja, X.; Frank-Comas, A.; Echeveste, P.; Bennasar-Figueras, A.; Ramis-Munar, G.; Gomila, M. R.; Agawin, N. S. R.
10.1101/2020.07.21.210740 — microbiology — Posted on 2020-07-21
1830 Integrative Proteomic Analysis of Posttranslational Modification in The Inflammatory Response
Ji, F.; Zhou, M.; Zhu, H.; Jiang, Z.; Li, Q.; Ouyang, X.; Lv, Y.; Zhang, S.; Wu, T.; Li, L.
10.1101/2020.07.20.212134 — immunology — Posted on 2020-07-21
1831 Spatiotemporal single-cell profiling of gastrointestinal GVHD reveals invasive and resident memory T cell states.
Tkachev, V.; Kaminski, J.; Potter, E. L.; Furlan, S. N.; Yu, A.; Hunt, D. J.; McGuckin, C.; Zheng, H.; Colonna, L.; Gerdemann, U.; Carlson, J.; Hoffman, M.; Olvera, J.; English, C.; Baldessari, A.; Panoskaltsis-Mortari, A.; Watkins, B.; Qayed, M.; Suessmuth, Y.; Betz, K.; Bratrude, B.; Langston, A.; Horan, J.; Ordovas-Montanes, J.; Shalek, A.; Blazar, B. R.; Roederer, M.; Kean, L. S.
10.1101/2020.07.20.212399 — immunology — Posted on 2020-07-21
1833 A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.
Leclerc, B.; de Nola, G.; Mougel, A.; Dezitter-Tarron, S.; Simonneau, C.; Forneris, F.; Adriaenssens, E.; Drobecq, H.; Gherardi, E.; Melnyk, O.; de Jonge, H.; Vicogne, J.
10.1101/2020.07.20.212654 — bioengineering — Posted on 2020-07-21
1836 THE ORIGIN OF A NEW HUMAN VIRUS: PHYLOGENETIC ANALYSIS OF THE EVOLUTION OF SARS-COV-2
Pereson, M. J.; Mojsiejczuk, L.; Martinez, A. P.; Flichman, D. M.; Garcia, G. H.; Di Lello, F. A.
10.1101/2020.07.21.212860 — evolutionary biology — Posted on 2020-07-21
1837 Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy
Patterson, E. I.; Elia, G.; Grassi, A.; Giordano, A.; Desario, C.; Medardo, M.; Smith, S. L.; Anderson, E. R.; Lorusso, E.; Lucente, M. S.; Lanave, G.; Lauzi, S.; Bonfanti, U.; Stranieri, A.; Martella, V.; Solari Basano, f.; Barrs, V. R.; Radford, A. D.; Hughes, G. L.; Paltrinieri, S.; Decaro, N.
10.1101/2020.07.21.214346 — microbiology — Posted on 2020-07-21
1838 Single cell RNA sequencing of blood antigen-presenting cells in severe Covid-19 reveals multi-process defects in antiviral immunity
Saichi, M.; Ladjemi, M. Z.; Korniotis, S.; Rousseau, C.; Ait-Hamou, Z.; Massenet, L.; Amblard, E.; Noel, F.; Marie, Y.; Bouteiller, D.; Medvedovic, J.; Pene, F.; Soumelis, V.
10.1101/2020.07.20.212837 — immunology — Posted on 2020-07-21
1839 Molecular mechanism of SARS-CoV-2 cell entry inhibition via TMPRSS2 by Camostat and Nafamostat mesylate
Hempel, T.; Raich, L.; Olsson, S.; Azouz, N. P.; Klingler, A. M.; Rothenberg, M. E.; Noe, F.
10.1101/2020.07.21.214098 — biophysics — Posted on 2020-07-21
1840 Intranasal Immunization with a Lentiviral Vector Coding for SARS-CoV-2 Spike Protein Confers Vigorous Protection in Pre-Clinical Animal Models
MAJLESSI, L.; Ku, M.-W.; Bourgine, M.; Authie, P.; Lopez, J.; Nemirov, K.; Moncoq, F.; Noirat, A.; Vesin, B.; Nevo, F.; Blanc, C.; Souque, P.; Simon, E.; Tabbal, H.; Mouquet, H.; Anna, F.; Martin, A.; Escriou, N.; Charneau, P.
10.1101/2020.07.21.214049 — immunology — Posted on 2020-07-21
1841 Severe perinatal hydrops fetalis in genome edited pigs with a biallelic five base pair deletion of the Marfan syndrome gene, FBN1
Tsang, H.-G.; Lillico, S.; Proudfoot, C.; McCulloch, M. E. B.; Markby, G. R.; Trejo-Reveles, V.; Whitelaw, C. B. A.; MacRae, V. E.; Summers, K. M.
10.1101/2020.07.20.213108 — molecular biology — Posted on 2020-07-21
1845 The mechanism underlying J-waves and T-waves in the electrocardiogram of mice and zebra finches
Offerhaus, J. A.; Snelderwaard, P. C.; Faber, J. W.; Riebe, K.; Jensen, B.; Boukens, B. J.
10.1101/2020.07.20.211763 — physiology — Posted on 2020-07-21
1851 The hunt for ancient prions: Archaeal prion-like domains form amyloids and substitute for yeast prion domains
Zajkowski, T.; Lee, M. D.; Mondal, S. S.; Carbajal, A.; Dec, R.; Brennock, P. D.; Piast, R. W.; Snyder, J. E.; Bense, N. B.; Dzwolak, W.; Jarosz, D. F.; Rothschild, L. J.
10.1101/2020.07.20.212902 — evolutionary biology — Posted on 2020-07-21
1852 A Method for the Automatic Normalization and 3D Facial Mesh Extraction from Head Magnetic Resonance Imaging
Sevillano, X.; Urena, D.; Gonzalez, R.; Fatjo-Vilas, M.; Salvador, R.; Pomarol-Clotet, E.; Martinez-Abadias, N.
10.1101/2020.07.20.211748 — bioinformatics — Posted on 2020-07-21
1854 Plant DNA polymerases alpha and delta mediate replication of geminiviruses
Wu, M.; Wei, H.; Tan, H.; Pan, S.; Liu, Q.; Bejarano, E. R.; Lozano-Duran, R.
10.1101/2020.07.20.212167 — plant biology — Posted on 2020-07-21
1855 Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility through distinct small RNA classes
Claycomb, J. M.; Charlesworth, A. G.; Lehrbach, N. J.; Seroussi, U.; Renaud, M. S.; Molnar, R. I.; Woock, J. R.; Aber, M. J.; Diao, A. J.; Ruvkun, G.
10.1101/2020.07.20.212050 — molecular biology — Posted on 2020-07-21
1856 Braconidae revisited: Bracon brevicornis genome showcases the potential of linked-read sequencing in identifying a putative complementary sex determiner gene
Ferguson, K. B.; Pannebakker, B. A.; Centurion, A.; van den Heuvel, J.; Nieuwenhuis, R.; Becker, F. F. M.; Schijlen, E.; Thiel, A.; Zwaan, B. J.; Verhulst, E. C.
10.1101/2020.07.20.211656 — genomics — Posted on 2020-07-21
1858 Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types.
Saez-Atienzar, S.; Bandres-Ciga, S.; Langston, R. G.; Kim, J. J.; Choi, S. W.; Reynolds, R. H.; The International ALS Genomics Consortium, ; ITALSGEN, ; Abramzon, Y.; Dewan, R.; Ahmed, S.; Landers, J. E.; Chia, R.; Ryten, M.; Cookson, M. R.; Nalls, M. A.; Chio, A.; Traynor, B. J.
10.1101/2020.07.20.211276 — genetics — Posted on 2020-07-21
1860 DynaMorph: learning morphodynamic states of human cells with live imaging and sc-RNAseq
Wu, Z.; Chhun, B. B.; Schmunk, G.; Kim, C.; Yeh, L.-H.; Nowakowski, T. J.; Zou, J.; Mehta, S. B.
10.1101/2020.07.20.213074 — cell biology — Posted on 2020-07-21
1863 A spatially resolved single cell atlas of human gastrulation
Tyser, R. C. V.; Mahammadov, E.; Nakanoh, S.; Vallier, L.; Scialdone, A.; Srinivas, S.
10.1101/2020.07.21.213512 — developmental biology — Posted on 2020-07-21
1864 MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells
Takeuchi, Y.; Murayama, T.; Yamawaki, K.; Natsume, T.; Marcela, R.-C. N.; Nishimura, T.; Kogure, Y.; Nakata, A.; Tominaga, K.; Sasahara, A.; Yano, M.; Ishikawa, S.; Ohta, T.; Ikeda, K.; Horie-Inoue, K.; Inoue, S.; Seki, M.; Suzuki, Y.; Sugano, S.; Enomoto, T.; Tanabe, M.; Tada, K.-i.; Kanemaki, M.; Okamoto, K.; Tojo, A.; Gotoh, N.
10.1101/2020.07.20.211961 — cancer biology — Posted on 2020-07-21
1866 Discovery of membrane-permeating cyclic peptides via mRNA display
Bowen, J. D.; Schloop, A. E.; Reeves, G. T.; Menegatti, S.; Rao, B. M.
10.1101/2020.07.20.212142 — biochemistry — Posted on 2020-07-21
1867 Dynamic multi-OMICs of glioblastoma reveal sensitivity to neddylation inhibition dependent on nuclear PTEN and DNA replication pathways
Ferdosi, S. R.; Taylor, B.; Lee, M.; Peng, S.; Tang, N.; Bybee, R.; Reid, G.; Hartmen, L.; Garcia-Mansfield, K.; Sharma, R.; Pirrotte, P.; Furnari, F.; Dhruv, H. D.; Berens, M. E.
10.1101/2020.07.21.212571 — cancer biology — Posted on 2020-07-21
1870 Sexual differences in genetic architecture in UK Biobank
Bernabeu, E.; Canela-Xandri, O.; Rawlik, K.; Talenti, A.; Prendergast, J.; Tenesa, A.
10.1101/2020.07.20.211813 — genomics — Posted on 2020-07-21
1875 Evidence for the Placenta-Brain Axis: Multi-Omic Kernel Aggregation Predicts Intellectual and Social Impairment in Children Born Extremely Preterm
Santos, H. P.; Bhattacharya, A.; Joseph, R. M.; Smeester, L.; Kuban, K. C.; Marsit, C. J.; O'Shea, T. M.; Fry, R. C.
10.1101/2020.07.19.211029 — genomics — Posted on 2020-07-21
1878 Non-invasive vagus nerve stimulation boosts mood recovery after effort exertion
Ferstl, M.; Teckentrup, V.; Lin, W. M.; Kräutlein, F.; Kühnel, A.; Klaus, J.; Walter, M.; Kroemer, N. B.
10.1101/2020.07.21.214353 — neuroscience — Posted on 2020-07-21
1880 Regulated assembly of the ER membrane protein complex
Pleiner, T.; Januszyk, K.; Tomaleri, G. P.; Oania, R. S.; Hazu, M.; Sweredoski, M. J.; Moradian, A.; Guna, A.; Voorhees, R. M.
10.1101/2020.07.20.213066 — molecular biology — Posted on 2020-07-21
1881 FER-mediated tyrosine phosphorylation and PIK3R2/p85β recruitment on IRS4 promotes the PI3K-AKT signaling pathway and tumorigenesis in ovarian cancer
Zhang, Y.; Xiong, X.; Zhu, Q.; Zhang, J.; Wang, Y.; Cao, J.; Chen, L.; Chen, S.; Hou, L.; Zhao, X.; Hao, P.; Zhuang, M.; Li, D.; Fan, G.
10.1101/2020.07.20.211417 — molecular biology — Posted on 2020-07-21
1887 BDdb: a comprehensive platform for exploration and utilization of birth defect multi-omics data
Zhang, D.; Sun, H.-X.; Zhou, Z.; Jiang, X.; Chen, D.; Zhou, S.; Huang, J.; Qu, S.; Gu, Y.; Zhang, X.; Jin, X.; Gao, Y.; Shen, Y.; Chen, F.
10.1101/2020.07.20.211391 — bioinformatics — Posted on 2020-07-21
1888 A disynaptic circuit in the globus pallidus controls locomotion inhibition
Aristieta, A.; Barresi, M.; Lindi, S. A.; Barriere, G.; Courtand, G.; de la Crompe, B.; Guilhemsang, L.; Gauthier, S.; Fioramonti, S.; Baufreton, J.; Mallet, N. P.
10.1101/2020.07.19.211318 — neuroscience — Posted on 2020-07-21
1890 An aberrant cytoplasmic intron retention programme is a blueprint for ALS-related RBP mislocalization
Tyzack, G. E.; Neeves, J.; Klein, P.; Crerar, H.; Ziff, O.; Taha, D. M.; Luisier, R.; Luscombe, N. M.; Patani, R.
10.1101/2020.07.20.211557 — neuroscience — Posted on 2020-07-21
1891 Dynamic causal modeling of layered magnetoencephalographic event-related responses
Ihle, S. J.; Bonaiuto, J. J.; Bestmann, S.; Stephan, K. E.; Barnes, G. R.; Heinzle, J.
10.1101/2020.07.20.208504 — neuroscience — Posted on 2020-07-21
1892 Lenticular nucleus volume predicts performance in real-time strategy game - cross-sectional and training approach using voxel-based morphometry
Kowalczyk, N.; Skorko, M.; Dobrowolski, P.; Kossowski, B.; Mysliwiec, M.; Hryniewicz, N.; Gaca, M.; Marchewka, A.; Kossut, M.; Brzezicka, A.
10.1101/2020.07.20.205864 — neuroscience — Posted on 2020-07-21
1893 Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates
Fahlberg, M. D.; Blair, R. V.; Doyle-Meyers, L. A.; Midkiff, C. C.; Zenere, G.; Russell-Lodrigue, K. E.; Monjure, C. J.; Haupt, E. H.; Penney, T. P.; Lehmicke, G.; Threeton, B. M.; Golden, N.; Datta, P. K.; Roy, C. J.; Bohm, R. P.; Maness, N. J.; Fischer, T.; Rappaport, J.; Vaccari, M.
10.1101/2020.07.21.213777 — immunology — Posted on 2020-07-21
1894 Activation of a neural stem cell transcriptional program in parenchymal astrocytes
Magnusson, J. P.; Zamboni, M.; Santopolo, G.; Mold, J. E.; Barrientos-Somarribas, M.; Talavera-Lopez, C.; Andersson, B.; Frisen, J.
10.1101/2020.07.20.211409 — neuroscience — Posted on 2020-07-21
1897 Unique contributions of sensory discrimination and gamma synchronization deficits to cognitive, clinical, and psychosocial functional impairments in schizophrenia
Koshiyama, D.; Miyakoshi, M.; Thomas, M. L.; Joshi, Y. B.; Molina, J. L.; Tanaka-Koshiyama, K.; Sprock, J.; Braff, D. L.; Swerdlow, N. R.; Light, G. A.
10.1101/2020.07.19.211193 — physiology — Posted on 2020-07-21
1902 Exploration of endogenous miRNA-200b/c activity and regulation through a functional dual fluorescence reporter
Gollavilli, P. N.; Parma, B.; Siddiqui, M. A.; Yang, H.; Ramesh, V.; Napoli, F.; Schwab, A.; Natesan, R.; Asangani, I. A.; Brabletz, T.; Pilarsky, C.; Ceppi, P.
10.1101/2020.07.19.210997 — molecular biology — Posted on 2020-07-21
1903 Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation
Cruz, A. R.; den Boer, M. A.; Strasser, J.; Beurskens, F. J.; de Haas, C. J. C.; Aerts, P.; Wang, G.; de Jong, R. N.; Bagnoli, F.; van Strijp, J.; van Kessel, K. P. M.; Schuurman, J.; Preiner, J.; Heck, A. J. R.; Rooijakkers, S. H. M.
10.1101/2020.07.20.212118 — microbiology — Posted on 2020-07-21
1906 Calibration and Evaluation of a Force Measurement Glove for Field-Based Monitoring of Manual Wheelchair Users
Anderson, A. J.; Hooke, A.; Jayaraman, C.; Burns, A.; Fortune, E.; Sosnoff, J. J.; Morrow, M.
10.1101/2020.07.19.169862 — bioengineering — Posted on 2020-07-21
1908 A Trypanosoma brucei ORFeome-based Gain-of-Function Library identifies genes that promote survival during melarsoprol treatment
Carter, M.; Gomez, S.; Gritz, S.; Larson, S.; Silva-Herzog, E.; Kim, H.-s.; Schulz, D.; Hovel-Miner, G. A.
10.1101/2020.07.19.211375 — genetics — Posted on 2020-07-21
1911 Evaluation of a novel multiplexed assay for determining IgG levels and functional activity to SARS-CoV-2.
Johnson, M.; Wagstaffe, H.; Gilmour, K. C.; Mai, A. L.; Lewis, J.; Hunt, A.; Sirr, J.; Bengt, C.; Grandjean, L.; Goldblatt, D.
10.1101/2020.07.20.213249 — immunology — Posted on 2020-07-21
1912 CENP-A overexpression drives distinct cell fates depending on p53 status
Jeffery, D. C. B.; Podsypanina, K.; Gatto, A.; Ponce Landete, R.; Bonneville, L.; Dumont, M.; Fachinetti, D.; Almouzni, G.
10.1101/2020.07.21.213496 — cancer biology — Posted on 2020-07-21
1913 SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB
Neufeldt, C. J.; Cerikan, B.; Cortese, M.; Frankish, J.; Lee, J.-Y.; Plociennikowska, A.; Heigwer, F.; Joecks, S.; Burkart, S. S.; Zander, D. Y.; Gendarme, M.; El Debs, B.; Halama, N.; Merle, U.; Boutros, M.; Binder, M.; Bartenschlager, R.
10.1101/2020.07.21.212639 — microbiology — Posted on 2020-07-21
1914 S protein-reactive IgG and memory B cell production after human SARS-CoV-2 infection includes broad reactivity to the S2 subunit
Nguyen-Contant, P.; Embong, A. K.; Kanagaiah, P.; Chaves, F.; Yang, H.; Branche, A. R.; Topham, D. J.; Sangster, M.
10.1101/2020.07.20.213298 — immunology — Posted on 2020-07-21
1915 Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut.
Zhi, H.; Behnsen, J.; Aron, A.; Subramanian, V.; Liu, J.; Gerner, R.; Petras, D.; Green, K.; Price, S.; Camacho, J.; Hillman, H.; Tjokrosurjo, J.; Montaldo, N.; Hoover, E.; Treacy-Abarca, S.; Gilston, B.; Skaar, E.; Chazin, W.; Garneau-Tsodikova, S.; Lawrenz, M.; Perry, R.; Nuccio, S.-P.; Dorrestein, P.; Raffatellu, M.
10.1101/2020.07.20.212498 — microbiology — Posted on 2020-07-21
1916 The Splicing Factor XAB2 interacts with ERCC1-XPF and XPG for RNA-loop processing during mammalian development
Goulielmaki, E.; Tsekrekou, M.; Batsiotos, N.; Ascensao-Ferreira, M.; Ledaki, E.; Stratigi, K.; Chatzinikolaou, G.; Topalis, P.; Kosteas, T.; Altmuller, J.; Demmers, J. A.; Barbosa-Morais, N. L.; Garinis, G. A.
10.1101/2020.07.20.211441 — genetics — Posted on 2020-07-21
1918 Bioactivity descriptors for uncharacterized compounds
Bertoni, M.; Duran-Frigola, M.; Badia-i-Mompel, P.; Orozco-Ruiz, M.; Guitart-Pla, O.; Aloy, P.
10.1101/2020.07.21.214197 — bioinformatics — Posted on 2020-07-21
1919 Mapping specificity, entropy, allosteric changes and substrates in blood proteases by a high-throughput protease screen
Uliana, F.; Vizovisek, M.; Acquasaliente, L.; Ciuffa, R.; Fossati, A.; Frommelt, F.; Gstaiger, M.; De Filippis, V.; auf dem Keller, U.; Aebersold, R.
10.1101/2020.07.20.211524 — biochemistry — Posted on 2020-07-21
1920 Once upon a time in the south: local drivers of plant invasion in the harsh sub-Antarctic islands
Bazzichetto, M.; Massol, F.; Carboni, M.; Lenoir, J.; Lembrechts, J. J.; Joly, R.; RENAULT, D.
10.1101/2020.07.19.210880 — ecology — Posted on 2020-07-21
1921 A sweet-tasting sugar drives aversive responses in caterpillars
Hong, Z.-Z.; Sun, L.; Hou, W.; Ma, Y.; Liu, L.; Zhao, X.; Yan, F.; Yin, X.; Wang, C.-Z.; Tang, Q.
10.1101/2020.07.20.213033 — animal behavior and cognition — Posted on 2020-07-21
1922 Signal Peptide of HIV-1 Envelope Functions to Modulate Glycosylation Impacting Exposure of V1V2 Epitopes
Upadhyay, C.; Feyznezhad, R.; Cao, L.; Chan, K.-W.; Liu, K.; Yang, W.; Zhang, H.; Yolitz, J.; Arthos, J.; Nadas, A.; Kong, X.-P.; Zolla-Pazner, S.; Hioe, C. E.
10.1101/2020.07.21.212183 — microbiology — Posted on 2020-07-21
1923 Vesicle Navigation of Microtubule Ends Distinguished by A Single Rate-Constant Model
Gramlich, M. W.; Balseiro Gomez, S.; Tabei, S. M. A.; Parkes, M.; Yogev, S.
10.1101/2020.07.21.214023 — biophysics — Posted on 2020-07-21
1928 Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors and suggest subtype specificity
Oliveira, A. S.; Ibarra, A. A.; Bermudez, I.; Casalino, L.; Gaieb, Z.; Shoemark, D. K.; Gallagher, T.; Sessions, R. B.; Amaro, R. E.; Mulholland, A. J.
10.1101/2020.07.16.206680 — biochemistry — Posted on 2020-07-21
1929 Comparative ACE2 variation and primate COVID-19 risk
Melin, A. D.; Janiak, M. C.; Marrone, F.; Arora, P. S.; Higham, J. P.
10.1101/2020.04.09.034967 — genetics — Posted on 2020-07-21
1931 Systematic modeling of SARS-CoV-2 protein structures
O'Donoghue, S. I.; Schafferhans, A.; Sikta, N.; Stolte, C.; Kaur, S.; Ho, B.; Anderson, S.; Procter, J. B.; Dallago, C.; Bordin, N.; Rost, B.; Adcock, M.
10.1101/2020.07.16.207308 — bioinformatics — Posted on 2020-07-21
1933 Integrative Vectors for Regulated Expression of SARS-CoV-2 Proteins Implicated in RNA Metabolism
Bresson, S.; Robertson, N.; Sani, E.; Turowski, T. W.; Shchepachev, V.; Kompauerova, M.; Spanos, C.; Helwak, A.; Tollervey, D.
10.1101/2020.07.20.211623 — cell biology — Posted on 2020-07-21
1936 BMP signalling directs a fibroblast-to-myoblast conversion at the connective tissue/muscle interface to pattern limb muscles
Esteves de Lima, J.; Blavet, C.; Bonnin, M.-A.; Hirsinger, E.; Comai, G.; Yvernogeau, L.; Bellenger, l.; Mella, S.; Nassari, S.; Robin, C.; Schweitzer, R.; Fournier-Thibault, C.; Tajbakhsh, S.; Relaix, F.; DUPREZ, D.
10.1101/2020.07.20.211342 — developmental biology — Posted on 2020-07-21
1940 Plexin-B1 mutation drives prostate cancer metastasis
Shorning, B.; Trent, N.; Griffiths, D. F.; Worzfeld, T.; Offermanns, S.; Masters, J.; Clarke, A. R.; Smalley, M. J.; Williamson, M.
10.1101/2020.07.19.203695 — cancer biology — Posted on 2020-07-21
1941 Three-dimensional beating dynamics of Chlamydomonas flagella
Mojiri, S.; Isbaner, S.; Muehle, S.; Jang, H.; Bae, A. J.; Gregor, I.; Gholami, A.; Enderlein, J.
10.1101/2020.07.20.212159 — biophysics — Posted on 2020-07-21
1942 Restoration of β-globin expression with optimally designed lentiviral vector for β-thalassemia treatment in Chinese patients
Ouyang, W.; Dong, G.; Zhao, W.; Li, J.; Zhou, Z.; Yang, G.; Liu, R.; Li, Y.; Zhang, Q.; Du, X.; Sun, H.; Gu, Y.; Lai, Y.; Liu, S.; Liu, C.
10.1101/2020.07.18.209759 — cell biology — Posted on 2020-07-21
1943 Ether lipid and sphingolipid expression patterns are G-protein coupled estrogen receptor 1-dependently altered in breast cancer cells
Hahnefeld, L.; Gruber, L.; Schoemel, N.; Fischer, C.; Mattjus, P.; Gurke, R.; Beretta, M.; Ferreiros Bouzas, N.; Geisslinger, G.; Wegner, M.-S.
10.1101/2020.07.20.212894 — cancer biology — Posted on 2020-07-21
1944 Light-powered reactivation of flagella: towards self-sustained movement of artificial cells
Ahmad, R.; Kleineberg, C.; Su, Y. J.; Goli Pozveh, S.; Bae, A. J.; Bodenschatz, E.; Sundmacher, K.; Vidakovich-Koch, T.; Gholami, A.
10.1101/2020.07.20.212191 — biophysics — Posted on 2020-07-21
1946 Comparative regulomics reveals pervasive selection on gene dosage following whole genome duplication
Gillard, G. B.; Groenvold, L.; Roesaeg, L.; Holen, M. M.; Monsen, O.; Koop, B. F.; Rondeau, E. B.; Gundappa, M. K.; Mendoza, J.; Macqueen, D.; Rohlfs, R. V.; Sandve, S. R.; Hvidsten, T. R.
10.1101/2020.07.20.212316 — evolutionary biology — Posted on 2020-07-20
1947 Neurometabolite Mapping Highlights Elevated Myo-inositol Profiles within the Developing Brain in Down Syndrome
Patkee, P. A.; Baburamani, A. A.; Long, K.; Dimitrova, R. V.; Ciarrusta, J.; Allsop, J.; Hughes, E.; Kangas, J.; McAlonan, G.; Rutherford, M.
10.1101/2020.07.20.211805 — neuroscience — Posted on 2020-07-20
1956 Optogenetic activation of spinal microglia triggers chronic pain in mice
Yi, M.-H.; Liu, Y. U.; Umpierre, A. D.; Chen, T.; Ying, Y.; Dheer, A.; Bosco, D. B.; Dong, H.; Wu, L.-J. D.
10.1101/2020.07.19.211250 — neuroscience — Posted on 2020-07-20
1958 Hot, humid air decontamination of aircraft confirmed that high temperature and high humidity are critical for inactivation of infectious, enveloped ribonucleic acid (RNA) virus
Buhr, T. L.; Young, A. A.; Borgers-Klonkowski, E. L.; Kennihan, N. L.; Barnette, H. K.; Minter, Z. A.; Bohmke, M. D.; Osborn, E. B.; Hamilton, S. M.; Kimani, M. B.; Hammon, M. W.; Miller, C. T.; Mackie, R. S.; Innocenti, J. M.; Bensman, M. D.; Gutting, B. W.; Lilly, S. D.; Hammer, E. E.; Yates, V. L.; Luck, B. B.
10.1101/2020.07.20.212365 — microbiology — Posted on 2020-07-20
1959 Coronavirus surveillance in Congo basin wildlife detects RNA of multiple species circulating in bats and rodents
Kumakamba, C.; Niama, F. R.; Muyembe, F.; Mombouli, J.-V.; Kingebeni, P. M.; Nina, R. A.; Lukusa, I. N.; Bounga, G.; NKawa, F.; Nkoua, C. G.; Atibu Losoma, J.; Mulembakani, P.; Makuwa, M.; Tamufe, U.; Gillis, A.; LeBreton, M.; Olson, S. H.; Cameron, K.; Reed, P.; Ondzie, A.; Tremeau-Bravard, A.; Smith, B. R.; Pante, J.; Schneider, B. S.; McIver, D. J.; Ayukekbong, J. A.; Hoff, N. A.; Rimoin, A. W.; Laudisoit, A.; Monagin, C.; Goldstein, T.; Joly, D. O.; Saylors, K.; Wolfe, N. D.; Rubin, E. M.; Bagamboula MPassi, R.; Muyembe Tamfum, J. J.; Lange, C.
10.1101/2020.07.20.211664 — microbiology — Posted on 2020-07-20
1961 Unique genomic features of crAss-like phages, the dominant component of the human gut virome
Yutin, N.; Benler, S.; Shmakov, S. A.; Wolf, Y. I.; Tolstoy, I.; Rayko, M.; Antipov, D.; Pevzner, P. A.; Koonin, E. V.
10.1101/2020.07.20.212944 — microbiology — Posted on 2020-07-20
1963 Competition for electrons favors N2O reduction in denitrifying Bradyrhizobium isolates
Gao, Y.; Mania, D.; Mousavi, S. A.; Lycus, P.; Arntzen, M. O.; Lindstrom, K.; Shapleigh, J. P.; Bakken, L. R.; Frostegard, A.
10.1101/2020.07.20.212696 — microbiology — Posted on 2020-07-20
1973 Multiscale interactions between plant part and a steep environmental gradient determine plant microbial composition in a tropical watershed
Bernard, J.; Wall, C. B.; Costantini, M. S.; Rollins, R. L.; Atkins, M. L.; Cabrera, F. P.; Feliciano, C. K. J.; Greene, A. L.; Kitamura, P. K.; Olmedo-Velarde, A.; Sirimalwatta, V. N. S.; Sung, H. W.; Thompson, L. P. M.; Vu, H. T.; Wilhite, C. J.; Amend, A. S.
10.1101/2020.07.20.212811 — microbiology — Posted on 2020-07-20
1979 The complexity of model-free and model-based learning strategies
Filipowicz, A. L. S.; Levine, J.; Piasini, E.; Tavoni, G.; Kable, J. W.; Gold, J. I.
10.1101/2019.12.28.879965 — neuroscience — Posted on 2020-07-20
1981 Community composition and development of the post-weaning piglet gut microbiome
Gaio, D.; DeMaere, M. Z.; Anantanawat, K.; Eamens, G. J.; Liu, M.; Zingali, T.; Falconer, L.; Chapman, T. A.; Djordjevic, S. P.; Darling, A. E.
10.1101/2020.07.20.211326 — microbiology — Posted on 2020-07-20
1984 Concerted action of kinesin-1 KIF5B and kinesin-3 KIF13B promotes efficient transport of exocytotic vesicles to microtubule plus ends
Serra-Marques, A.; Martin, M.; Katrukha, E. A.; Grigoriev, I.; Peeters, C. A. E.; Liu, Q.; Hooikaas, P. J.; Yao, Y.; Smal, I.; Pedersen, L. B.; Meijering, E.; Kapitein, L. C.; Akhmanova, A.
10.1101/2020.04.06.027862 — cell biology — Posted on 2020-07-20
1986 Association of gut microbiota with cerebral cortex and cerebrovascular abnormality in human mild traumatic brain injury
Bai, L.; Li, T.; Zhang, M.; Wang, S.; Gan, S.; Jia, X.; Yang, X.; Sun, Y.; Xiong, F.; Yin, B.; Ren, Y.; Bai, G.; Yan, Z.; Mu, X.; Zhu, F.
10.1101/2020.07.19.211227 — microbiology — Posted on 2020-07-20
1987 Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract
Green, S. I.; Gu Liu, C.; Yu, M.; Gibson, S.; Salmen, W.; Rajan, A.; Carter, H. E.; Clark, J. R.; Song, X.; Ramig, R. F.; Trautner, B. W.; Kaplan, H. B.; Maresso, A. W.
10.1101/2020.07.20.212829 — microbiology — Posted on 2020-07-20
1993 Can biomass distribution across trophic levels predict trophic cascades?
Galiana, N.; Arnoldi, J.-F.; Barbier, M.; Acloque, A.; de Manzancourt, C.; Loreau, M.
10.1101/2020.04.04.025460 — ecology — Posted on 2020-07-20
1997 Timing matters: The temporal representation of experience in subjective mood reports
Keren, H.; Zheng, C.; Jangraw, D.; Chang, K.; Vitale, A.; Nielson, D. M.; Rutledge, R.; Pereira, F.; Stringaris, A.
10.1101/815944 — neuroscience — Posted on 2020-07-20
1999 Self-assembly of multi-component mitochondrial nucleoids via phase separation
Feric, M.; Demarest, T. G.; Tian, J.; Croteau, D. L.; Bohr, V. A.; Misteli, T.
10.1101/822858 — cell biology — Posted on 2020-07-20
2000 Blood-brain barrier transport using a high-affinity, brain-selective VNAR (Variable Domain of New Antigen Receptor) antibody targeting transferrin receptor 1
Stocki, P.; Szary, J. M.; Rasmussen, C. L.; Demydchuk, M.; Northall, L.; Bahu Logan, D.; Gauhar, A.; Thei, L.; Moos, T.; Walsh, F. S.; Rutkowski, J. L.
10.1101/816900 — neuroscience — Posted on 2020-07-20
2005 Molecular estimation of neurodegeneration pseudotime in older brains
Mukherjee, S.; Heath, L.; Preuss, C.; Jayadev, S.; Garden, G. A.; Greenwood, A. K.; Sieberts, S. K.; De Jager, P. L.; Ertekin-Taner, N.; Carter, G. W.; Mangravite, L. M.; Logsdon, B.
10.1101/686824 — neuroscience — Posted on 2020-07-20
2007 Worldwide Geographical and Temporal Analysis of SARS-CoV-2 Haplotypes shows Differential Distribution Patterns
Justo Arevalo, S.; Zapata Sifuentes, D.; Huallpa Robles, C.; Landa Bianchi, G.; Castillo Chavez, A.; Garavito-Salini Casas, R.; Uceda-Campos, G.; Pineda Chavarria, R.
10.1101/2020.07.12.199414 — genomics — Posted on 2020-07-20
2008 Vinegar and Its Active Component Acetic Acid Inhibit SARS-CoV-2 Infection In Vitro and Ex Vivo
Pagani, I.; Ghezzi, S.; Clementi, M.; Poli, G.; Bussi, M.; Pianta, L.; Trimarchi, M.; Vicenzi, E.
10.1101/2020.07.08.193193 — microbiology — Posted on 2020-07-20
2009 Structural analysis of SARS-CoV-2 genome and predictions of the human interactome
Vandelli, A.; Monti, M.; Milanetti, E.; Rupert, J.; Zacco, E.; Bechara, E.; Delli Ponti, R.; Tartaglia, G. G.
10.1101/2020.03.28.013789 — bioinformatics — Posted on 2020-07-20
2011 De novo design of modular and tunable allosteric biosensors
Quijano-Rubio, A.; Yeh, H.-W.; Park, J.; Lee, H.; Langan, R. A.; Boyken, S. E.; Lajoie, M. J.; Cao, L.; Chow, C. M.; Miranda, M. C.; Wi, J.; Hong, H. J.; Stewart, L.; Oh, B.-H.; Baker, D.
10.1101/2020.07.18.206946 — synthetic biology — Posted on 2020-07-20
2013 The short and long-range RNA-RNA Interactome of SARS-CoV-2
Ziv, O.; Price, J.; Shalamova, L.; Kamenova, T.; Goodfellow, I.; Weber, F.; Miska, E. A.
10.1101/2020.07.19.211110 — molecular biology — Posted on 2020-07-20
2014 Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2
Onabajo, O. O.; Banday, A. R.; Yan, W.; Obajemu, A.; Stanifer, M. L.; Santer, D. M.; Florez-Vargas, O.; Piontkivska, H.; Vargas, J.; Kee, C.; Tyrrell, D. L.; Mendoza, J. L.; Boulant, S.; Prokunina-Olsson, L.
10.1101/2020.07.19.210955 — genetics — Posted on 2020-07-20
2015 A human disease model of SARS-CoV-2-induced lung injury and immune responses with a microengineered organ chip
Zhang, M.; Wang, P.; Luo, R.; Wang, Y.; Li, Z.; Guo, Y.; Yao, Y.; Li, M.; Tao, T.; Chen, W.; Han, J.; Liu, H.; Cui, K.; Zhang, X.; Zheng, Y.; Qin, J.
10.1101/2020.07.20.211789 — bioengineering — Posted on 2020-07-20
2016 Inhibitors of VPS34 and lipid metabolism suppress SARS-CoV-2 replication
Silvas, J. A.; Jureka, A. S.; Nicolini, A. M.; Chvatal, S. A.; Basler, C. F.
10.1101/2020.07.18.210211 — microbiology — Posted on 2020-07-20
2018 The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models
Stegmann, K. M.; Dickmanns, A.; Gerber, S.; Nikolova, V.; Klemke, L.; Manzini, V.; Schloesser, D.; Bierwirth, C.; Freund, J.; Sitte, M.; Lugert, R.; Salinas, G.; Goerlich, D.; Wollnik, B.; Gross, U.; Dobbelstein, M.
10.1101/2020.07.18.210013 — molecular biology — Posted on 2020-07-20
2019 Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome
Zhang, K.; Zheludev, I. N.; Hagey, R. J.; Wu, M. T.-P.; Haslecker, R.; Hou, Y. J.; Kretsch, R.; Pintilie, G. D.; Rangan, R.; Kladwang, W.; Li, S.; Pham, E. A.; Bernardin, C.; Baric, R. S.; Sheahan, T. P.; Dsouza, V.; Glenn, J. S.; Chiu, W.; Das, R.
10.1101/2020.07.18.209270 — biochemistry — Posted on 2020-07-20
2022 Selection and Biodiversity change
Godsoe, W.; Eisen, K. E.; Stanton, D.; Sirianni, K. M.
10.1101/527028 — ecology — Posted on 2020-07-20
2023 Post-intervention Epidemiology of STH in Bangladesh: data to sustain the gains
Imtiaz, R.; Dhakal, S.; Karim, M. J.; Al Kawsar, A.; Irish, J.; Rahman, M. M.; Tupps, C.; Kabir, A.
10.1101/2020.07.17.208355 — scientific communication and education — Posted on 2020-07-20
2025 Systematic modeling of SARS-CoV-2 protein structures
O'Donoghue, S. I.; Schafferhans, A.; Sikta, N.; Stolte, C.; Kaur, S.; Ho, B.; Anderson, S.; Procter, J. B.; Dallago, C.; Bordin, N.; Rost, B.; Adcock, M.
10.1101/2020.07.16.207308 — bioinformatics — Posted on 2020-07-20
2026 Aβ-induced synaptic injury is mediated by presynaptic expression of amyloid precursor protein (APP) in hippocampal neurons
Vicario-Orri, E.; Kasuga, K.; Tyan, S.-H.; Chiang, K.; Viana da Silva, S.; Bushong, E. A.; DeLoach, K.; Ling, I.-F.; Luo, L.; Ellisman, M. H.; Leutgeb, S.; Koo, E. H.
10.1101/2020.07.18.210344 — neuroscience — Posted on 2020-07-20
2027 Common Garlic (Allium sativum L.) has Potent Anti-Bacillus anthracis Activity
Kaur, R.; Tiwari, A.; Manish, M.; Maurya, I. K.; Bhatnagar, R.; Singh, S.
10.1101/162214 — microbiology — Posted on 2020-07-20
2030 Sarcolambans are phospholamban- and sarcolipin-like regulators of the sarcoplasmic reticulum calcium pump SERCA
Bak, J. J.; Aguayo-Ortiz, R.; Khan, M. B.; Robia, S. L.; Lemieux, M. J.; Espinoza-Fonseca, L. M.; Young, H. S.
10.1101/2020.07.19.211243 — biochemistry — Posted on 2020-07-19
2031 Multistep changes in amyloid structure that are induced by cross-seeding on a rugged energy landscape
Yuzu, K.; Yamamoto, N.; Noji, M.; So, M.; Goto, Y.; Iwasaki, T.; Tsubaki, M.; Chatani, E.
10.1101/2020.07.19.211284 — biochemistry — Posted on 2020-07-19
2032 A Sequence determinant in 3'UTR of mRNAs for Nuclear Retention by Paraspeckles
Jacq, A.; Becquet, D.; Boyer, B.; Guillen, S.; Bello-Goutierrez, M.-M.; Blanchard, M.-P.; Villard, C.; Belghazi, M.; Torres, M.; Franc, J.-L.; Francois-Bellan, A.-M.
10.1101/2020.07.19.206417 — molecular biology — Posted on 2020-07-19
2034 Cancer cells are uniquely susceptible to accumulation of MMBIR mutations
Osia, B. A.; Alsulaiman, T.; Jackson, T.; Kramara, J.; Oliveira, S.; Malkova, A.
10.1101/2020.07.19.209445 — genetics — Posted on 2020-07-19
2037 RNA-binding protein FXR1 drives cMYC translation by mRNA circularization through eIF4F recruitment in ovarian cancer
George, J.; Li, Y.; Parashar, D.; Tsaih, S.-W.; Gupta, P.; Geethadevi, A.; Kadembari, I.; Ghosh, C.; Sun, Y.; Ramchandran, R.; Rader, J. S.; Rui, H.; Dey, M.; Pradeep, S.; Chaluvally-Raghavan, P.
10.1101/2020.07.19.210252 — cancer biology — Posted on 2020-07-19
2038 Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles
Hershewe, J. M.; Warfel, K. F.; Iyer, S. M.; Peruzzi, J. A.; Sullivan, C. J.; Roth, E. W.; DeLisa, M. P.; Kamat, N. P.; Jewett, M. C.
10.1101/2020.07.19.211201 — synthetic biology — Posted on 2020-07-19
2039 A multipass membrane protein interacts with the cGMP-dependent protein kinase to regulate critical calcium signals in malaria parasites
Balestra, A. C.; Koussis, K.; Klages, N.; Howell, S. A.; Flynn, H. R.; Bantscheff, M.; Pasquarello, C.; Perrin, A. J.; Brusini, L.; Arboit, P.; Sanz, O.; Peces-Barba Castano, L.; Withers-Martinez, C.; Hainard, A.; Ghidelli-Disse, S.; Snijders, A. P.; Baker, D. A.; Blackman, M. J.; Brochet, M.
10.1101/2020.07.18.209973 — microbiology — Posted on 2020-07-19
2042 Enzyme-constrained models and omics analysis of Streptomyces coelicolor reveal metabolic changes that enhance heterologous production
Sulheim, S.; Kumelj, T.; van Dissel, D.; Salehzadeh-Yazdi, A.; Du, C.; van Wezel, G. P.; Nieselt, K.; Almaas, E.; Wentzel, A.; Kerkhoven, E. J.
10.1101/796722 — systems biology — Posted on 2020-07-19
2044 Multiple types of navigational information are diffusely and independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-07-19
2045 Piezo1 Mediates Keratinocyte Mechanotransduction
Moehring, F.; Mikesell, A. R.; Sadler, K. E.; Menzel, A. D.; Stucky, C. L.
10.1101/2020.07.19.211086 — neuroscience — Posted on 2020-07-19
2046 A single-cell transcriptome atlas of the aging human and macaque retina
Yi, W.; Lu, y.; Zhong, S.; zhang, m.; Sun, L.; Dong, H.; Wang, M.; Wei, M.; Xie, H.; Qu, H.; Peng, R.; Hong, J.; Yao, Z.; Tong, Y.; Wang, W.; Ma, Q.; Liu, z.; Ma, Y.; Li, S.; Yin, C.; Liu, J.; Ma, C.; Wang, X.; Wu, Q.; Xue, T.
10.1101/2020.07.17.207977 — neuroscience — Posted on 2020-07-19
2047 Musical skills can be decoded from magnetic resonance images
Puoliväli, T.; Sipola, T.; Thiede, A.; Kliuchko, M.; Bogert, B.; Toiviainen, P.; Nandi, A. K.; Parkkonen, L.; Brattico, E.; Ristaniemi, T.; Parviainen, T.
10.1101/2020.07.19.210906 — neuroscience — Posted on 2020-07-19
2048 How to characterize a strain? The neglected influence of clonal heterogeneity on the phenotypes of industrial Saccharomyces
Racz, H. V.; Mukhtar, F.; Imre, A.; Radai, Z.; Gombert, A. K.; Ratonyi, T.; Nagy, J.; Pocsi, I.; Pfliegler, W. P.
10.1101/2020.07.19.211094 — microbiology — Posted on 2020-07-19
2051 Exome-wide association studies in general and long-lived populations identify genetic variants related to human age
Sin-Chan, P.; Gosalia, N.; Gao, C.; Van Hout, C. V.; Ye, B.; Marcketta, A.; Li, A. H.; O'Dushlaine, C.; Li, D.; Overton, J. D.; Reid, J. D.; Baras, A.; Genetics Center, R.; Carey, D. J.; Ledbetter, D. H.; Rader, D.; Ritchie, M. D.; Damrauer, S. M.; Milman, S.; Barzilai, N.; Glass, D. J.; Economides, A. N.; Shuldiner, A. R.
10.1101/2020.07.19.188789 — genetics — Posted on 2020-07-19
2052 Species-Specific Responses of Bird Song Output in the Presence of Drones
Wilson, A. M.; Boyle, K. S.; Gilmore, J. L.; Kiefer, C. J.; Walker, M. F.
10.1101/2020.07.19.211045 — ecology — Posted on 2020-07-19
2055 Single-cell in vivo brain optogenetic stimulation by two-photon excitation fluorescence transfer
Tong, L.; Yuan, P.; Chen, M.; Chen, F.; Bewersdorf, J.; Zhou, J. Z.; Grutzendler, J.
10.1101/2020.06.29.179077 — neuroscience — Posted on 2020-07-19
2056 The Dystonia Gene THAP1 Controls DNA Double Strand Break Repair Choice
Shinoda, K.; Zong, D.; Callen, E.; Wu, W.; Dumitrache, L. C.; Belinky, F.; Wong, N.; Ishikawa, m.; Stanlie, A.; Ehrlich, M.; McKinnon, P.; nussenzweig, a.
10.1101/2020.07.19.210773 — molecular biology — Posted on 2020-07-19
2057 Statistical classification of dynamic bacterial growth with sub-inhibitory concentrations of nanoparticles and its implications for disease treatment
Jones, A.-A. D.; Medina-Cruz, D.; Kim, N. Y.; Mi, G.; Bartomeu Garcia, C.; Baranda-Pellejero, L.; Bassous, N.; Webster, T. J.
10.1101/2020.07.19.210930 — microbiology — Posted on 2020-07-19
2059 Base-resolution models of transcription factor binding reveal soft motif syntax
Avsec, Z.; Weilert, M.; Shrikumar, A.; Krueger, S.; Alexandari, A.; Dalal, K.; Fropf, R.; McAnany, C.; Gagneur, J.; Kundaje, A.; Zeitlinger, J.
10.1101/737981 — genomics — Posted on 2020-07-19
2062 Identification and Characterization of a B-Raf Kinase Alpha Helix Critical for the Activity of MEK Kinase in MAPK Signaling
Nguyen, D.; Lin, L. Y.; Zhou, J.; Kibby, E.; Sia, T.; Tillis, T.; Vapuryan, N.; Xu, M.-R.; Potluri, R.; Shin, Y.; Erler, E.; Bronkema, N.; Boehmler, D.; Chung, C.; Burkhard, C.; Grasso, M.; Acevedo, L. A.; Marmorstein, R.; Fera, D.
10.1101/2020.07.19.211177 — biochemistry — Posted on 2020-07-19
2064 Novel algorithms for PFGE bacterial typing: Number of co-migrated DNA fragments, linking PFGE to WGS results and computer simulations for evaluation of PulseNet international typing protocols
Adam, I. E.-k. M.; Abdokashif, I.; Elrashid, A.; Bayoumi, H.; Musa, A.; Abdulgyom, E.; Mamoun, S.; Alnagar, S.; Mohammed, W.; El-khateeb, A.; Oshi, M.; El-bakri, F.
10.1101/2020.07.05.188623 — bioinformatics — Posted on 2020-07-19
2070 An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19
McGregor, R.; Chauss, D.; Freiwald, T.; Yan, B.; Wang, L.; Nova-Lamperti, E.; Zhang, Z.; Teague, H.; West, E.; Bibby, J.; Kelly, A.; Malik, A.; Freeman, A.; Schwartz, D.; Portilla, D.; John, S.; Lavender, P.; Lionakis, M. S.; Mehta, N. N.; Kemper, C.; Cooper, N.; Lombardi, G.; Laurence, A.; Kazemian, M.; Afzali, B.
10.1101/2020.07.18.210161 — immunology — Posted on 2020-07-19
2073 Lethality of SARS-CoV-2 infection in K18 human angiotensin converting enzyme 2 transgenic mice
Oladunni, F.; Park, J.-G.; Pino Tamayo, P.; Gonzalez, O.; Ahkter, A.; Allue Guardia, A.; Olmo-Fontanez, A.; Gautam, S.; Garcia Vilanova, A.; Ye, C.; Chiem, K.; Headley, C.; Dwivedi, V.; Parodi, L.; Alfson, K.; Staples, H.; Schami, A.; Garcia, J.; Whigham, A.; Platt, R. N.; Gazi, M.; Martinez, J. C.; Chuba, C.; Earley, S.; Rodriguez, O.; Davis Mdaki, S.; Kavelish, K.; Escalona, R.; Hallam, C.; Christie, C.; Patterson, J.; Anderson, T.; Carrion, R.; Dick, E.; Hall-Ursone, S.; Schlesinger, L. S.; Kaushal, D.; Giavedoni, L. D.; Alvarez, X.; Turner, J.; Martinez-Sobrido, L.; Torrelles, J. B.
10.1101/2020.07.18.210179 — microbiology — Posted on 2020-07-19
2074 Visual effort moderates a self-correcting nonlinear postural control policy
Kelty-Stephen, D. G.; Lee, I.-C.; Carver, N. S.; Newell, K. M.; Mangalam, M.
10.1101/2020.07.17.209502 — neuroscience — Posted on 2020-07-19
2076 MRI Brain Templates of the Male Yucatan Minipig
Norris, C.; Lisinski, J.; Fievisohn, E.; VanMeter, J. W.; VandeVord, P.; LaConte, S. M.
10.1101/2020.07.17.209064 — neuroscience — Posted on 2020-07-19
2080 Planomonospora: a Metabolomics Perspective on an Underexplored Actinobacteria Genus
Zdouc, M. M.; Iorio, M.; Maffioli, S. I.; Crüsemann, M.; Donadio, S.; Sosio, M.
10.1101/2020.07.19.210815 — microbiology — Posted on 2020-07-19
2082 Regression of Human Breast Carcinoma in Nude Mice After Adsflt Gene Therapy is Mediated by Tumor Vascular Endothelial Cell Apoptosis
Felici, A.; Bottaro, D. P.; Mangoni, A.; Reusch, P.; Marme, D.; Kovesdi, I.; De Silva, D. M.; Lee, Y. H.; Capogrossi, M. C.; Mühlhauser, J.
10.1101/2020.07.19.210856 — cancer biology — Posted on 2020-07-19
2083 Toxigenic and zoonotic Corynebacterium ulcerans emerges from widespread hedgehog disease
Martel, A.; Boyen, F.; Rau, J.; Eisenberg, T.; Sing, A.; Berger, A.; Chiers, K.; Van Praet, S.; Verbanck, S.; Vervaeke, M.; Pasmans, F.
10.1101/2020.07.17.208827 — microbiology — Posted on 2020-07-19
2084 Deep learning neural network prediction method improves proteome profiling of vascular sap of grapevines during Pierce's disease development
Duarte Sagawa, C. H.; Zaini, P. A.; Assis, R. d. A. B.; Saxe, H.; Salemi, M.; Jacobson, A.; Phinney, B. S.; Dandekar, A. M.
10.1101/2020.07.18.210153 — genomics — Posted on 2020-07-19
2086 Humic acids enrich the plant microbiota with bacterial candidates for the suppression of pathogens
Silva, M. S.; Tavares, O. C.; Ribeiro, T. G.; Silva, C. S.; Silva, C. S.; Garcia-Mina, J. M.; Baldani, V. L.; Garcia, A. C.; Berbara, R. L.; Jesus, E. C.
10.1101/2020.07.18.210427 — microbiology — Posted on 2020-07-19
2088 Ecological load and balancing selection in circumboreal barnacles
Nunez, J. C. B.; Rong, S.; Damian-Serrano, A.; Burley, J. T.; Elyanow, R.; Ferranti, D. A.; Neil, K. B.; Glenner, H.; Rosenblad, M. A.; Blomberg, A.; Johannesson, K.; Rand, D. M.
10.1101/2020.07.18.209569 — evolutionary biology — Posted on 2020-07-19
2089 Muscle cell type diversification driven by extensive gene duplications
Cole, A. G.; Kaul, S.; Jahnel, S. M.; Steger, J.; Zimmermann, B.; Reischl, R.; Richards, G. S.; Rentzsch, F.; Steinmetz, P.; Technau, U.
10.1101/2020.07.19.210658 — developmental biology — Posted on 2020-07-19
2090 Dynamic regulatory module networks for inference of cell type specific transcriptional networks
Fotuhi Siahpirani, A.; Chasman, D.; Seirup, M.; Knaack, S.; Sridharan, R.; Stewart, R.; Thomson, J.; Roy, S.
10.1101/2020.07.18.210328 — bioinformatics — Posted on 2020-07-19
2091 A Whole Blood Thrombus Mimic: Constitutive Behavior Under Simple Shear
Sugerman, G. P.; Kakaletsis, S.; Thakkar, P.; Chokshi, A.; Parekh, S. H.; Rausch, M. K.
10.1101/2020.07.19.210732 — bioengineering — Posted on 2020-07-19
2092 Carotenogenesis of Staphylococcus aureus: new insights and impact on membrane biophysical properties
Lopez, G.-D.; Suesca, E.; Alvarez-Rivera, G.; Rosato, A.; Ibanez, E.; Cifuentes, A.; Leidy, C.; Carazzone, C.
10.1101/2020.07.19.210609 — biochemistry — Posted on 2020-07-19
2096 Agro-morphological, yield, and genotyping-by-sequencing data of selected wheat germplasm
Islam, M.; Abdullah, ; Zubaida, B.; Shafqat, N.; Masood, R.; Khan, U.; Waseem, S.; Waheed, M. T.; Haider, W.; Tahir, J.; Ahmed, I.; Naeem, M.; Ahmad, H.
10.1101/2020.07.18.209882 — genetics — Posted on 2020-07-19
2097 Phenotypic plasticity explains violation of Dollo's law
Visser, B.; Alborn, H. T.; Rondeaux, S.; Haillot, M.; Hance, T.; Rebar, D.; Riederer, J. M.; Tiso, S.; van Eldijk, T. J. B.; Weissing, F. J.; Nieberding, C. M.
10.1101/2020.07.17.208876 — evolutionary biology — Posted on 2020-07-19
2098 Evolutionary Conservation and Essential Function of Human and Maize RNA Binding Motif Protein 48 (RBM48) in U12-Type Intron Splicing
Siebert, A. E.; Corll, J.; Gronevelt, J. P.; Levine, L.; Hobbs, L. M.; Kenney, C.; Davenport, R.; Settles, A. M.; Barbazuk, W. B.; Westrick, R. J.; Madlambayan, G. J.; Lal, S.
10.1101/2020.07.18.209528 — evolutionary biology — Posted on 2020-07-19
2099 Spider webs as eDNA tool for biodiversity assessment of life's domains
Gregoric, M.; Kutnjak, D.; Bacnik, K.; Gostincar, C.; Pecman, A.; Ravnikar, M.; Kuntner, M.
10.1101/2020.07.18.209999 — ecology — Posted on 2020-07-19
2100 The structure and spontaneous curvature of clathrin lattices at the plasma membrane.
Sochacki, K. A.; Heine, B. L.; Haber, G. J.; Jimah, J. R.; Prasai, B.; Alfonzo-Mendez, M. A.; Roberts, A. D.; Somasundaram, A.; Hinshaw, J. E.; Taraska, J. W.
10.1101/2020.07.18.207258 — cell biology — Posted on 2020-07-19
2102 Generation of ordered protein assemblies using rigid three-body fusion
Vulovic, I.; Yao, Q.; Park, Y.-J.; Courbet, A.; Norris, A.; Busch, F.; Sahasrabuddhe, A.; Merten, H.; Sahtoe, D. D.; Ueda, G.; Fallas, J. A.; Hsia, Y.; Weaver, S. J.; Langan, R. A.; Pluckthun, A.; Wysocki, V. H.; Veesler, D.; Jensen, G. J.; Baker, D.
10.1101/2020.07.18.210294 — synthetic biology — Posted on 2020-07-19
2105 Delay-Induced Uncertainty in Physiological Systems
Karamched, B. R.; Albers, D.; Hripcsak, G.; Ott, W.
10.1101/2020.07.17.209544 — physiology — Posted on 2020-07-19
2107 Exposure to maternal high-fat diet induces extensive changes in the brain of adult offspring
Fernandes, D. J.; Spring, S.; Roy, A. R.; Qiu, L. R.; Yee, Y.; Neiman, B. J.; Lerch, J. P.; Palmert, M. R.
10.1101/2020.07.17.209551 — neuroscience — Posted on 2020-07-19
2109 The Effect of Refractive Blur in the Vividness of Mental Imagery
Suresh, T.; Roy, A.; Shaikh, A. I. A.; Rajkumar, J. L.; Mathew, V.; Prabhakar, A. T.
10.1101/2020.07.17.208017 — neuroscience — Posted on 2020-07-19
2111 Visual effort moderates postural cascade dynamics
Mangalam, M.; Lee, I.-C.; Newell, K. M.; Kelty-Stephen, D. G.
10.1101/2020.07.17.209486 — neuroscience — Posted on 2020-07-19
2116 Protein homeostasis imprinting across evolution
Koutsandreas, T.; Chevet, E.; Chatziioannou, A.; Felden, B.
10.1101/2020.07.19.210591 — bioinformatics — Posted on 2020-07-19
2119 Neuroanatomical dissociations of syntax and semantics revealed by lesion-symptom mapping
Matchin, W.; Basilakos, A.; den Ouden, D.-B.; Stark, B.; Hickok, G.; Fridriksson, J.
10.1101/2020.07.17.209262 — neuroscience — Posted on 2020-07-19
2120 Cortical recycling in high-level visual cortex during childhood development
Nordt, M.; Gomez, J.; Natu, V.; Rezai, A. A.; Finzi, D.; Kular, H.; Grill-Spector, K.
10.1101/2020.07.18.209783 — neuroscience — Posted on 2020-07-19
2122 Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography
Nazarov, S.; Bezler, A.; Hatzopoulos, G.; Nemcikova Villimova, V.; Demurtas, D.; Le Guennec, M.; Guichard, P.; Gönczy, P.
10.1101/2020.07.17.208082 — cell biology — Posted on 2020-07-18
2124 Quantitative definition of neurobehavior, vision, hearing and brain volumes in macaques congenitally exposed to Zika virus
Koenig, M. R.; Razo, E.; Mitzey, A.; Newman, C. M.; Dudley, D. M.; Breitbach, M. E.; Semler, M. R.; Stewart, L. M.; Weiler, A. M.; Rybarczyk, S.; Bach, K. M.; Mohns, M. M.; Simmons, H. A.; Mejia, A.; Fritsch, M.; Dennis, M.; Teixeira, L. B. C.; Schotzko, M. L.; Nork, T. M.; Rasmussen, C. A.; Katz, A.; Nair, V.; Hou, J.; Hartman, A.; Ver Hoeve, J.; Kim, C.; Schneider, M. L.; Ausderau, K.; Kohn, S.; Jaeger, A. S.; Aliota, M. T.; Hayes, J. M.; Schultz-Darken, N.; Eickhoff, J.; Antony, K. M.; Noguchi, K.; Zeng, X.; Permar, S.; Prabhakaran, V.; Capuano, S.; Friedrich, T. C.; Golos, T. G.; O'Connor,
10.1101/726018 — microbiology — Posted on 2020-07-18
2126 Neural circuit mechanisms for steering control in walking Drosophila
Rayshubskiy, A.; Holtz, S. L.; D'Alessandro, I.; Li, A. A.; Vanderbeck, Q. X.; Haber, I. S.; Gibb, P. W.; Wilson, R. I.
10.1101/2020.04.04.024703 — neuroscience — Posted on 2020-07-18
2129 TMEM184B promotes pruriceptive neuron specification to allow itch sensitivity
Larsen, E. G.; Cho, T. S.; McBride, M. L.; Feng, J.; Manivannan, B.; Madura, C.; Klein, N. E.; Wright, E. B.; Garcia-Verdugo, H. D.; Jarvis, C.; Khanna, R.; Hu, H.; Largent-Milnes, T. M.; Bhattacharya, M. R. C.
10.1101/2020.01.25.919902 — neuroscience — Posted on 2020-07-18
2132 Distinct signatures of calcium activity in brain pericytes
Glück, C.; Ferrari, K. D.; Keller, A.; Saab, A. S.; Stobart, J. L.; Weber, B.
10.1101/2020.07.16.207076 — neuroscience — Posted on 2020-07-18
2134 The SERCA residue Glu340 mediates inter-domain communication that guides Ca2+ transport
Geurts, M. M. G.; Clausen, J. D.; Arnou, B.; Montigny, C.; Lenoir, G.; Corey, R. A.; Jaxel, C.; Moeller, J.; Nissen, P.; Andersen, J. P.; le Maire, M.; Bublitz, M.
10.1101/2020.06.22.165365 — molecular biology — Posted on 2020-07-18
2135 Competition sensing alters antibiotic production in Streptomyces
Westhoff, S.; Kloosterman, A.; van Hoesel, S. F. A.; van Wezel, G. P.; Rozen, D. E.
10.1101/2020.01.24.918557 — microbiology — Posted on 2020-07-18
2136 Haloferax volcanii immersed liquid biofilms develop independently of known biofilm machineries and exhibit rapid honeycomb pattern formation
Schiller, H.; Schulze, S.; Mutan, Z.; de Vaulx, C.; Runcie, C.; Schwartz, J.; Rados, T.; Bisson Filho, A. W.; Pohlschroder, M.
10.1101/2020.07.18.206797 — microbiology — Posted on 2020-07-18
2137 Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum
Pholcharee, T.; Oyen, D.; Flores-Garcia, Y.; Gonzalez-Paez, G.; Han, Z.; Williams, K. L.; Volkmuth, W.; Emerling, D.; Locke, E.; King, C. R.; Zavala, F.; Wilson, I. A.
10.1101/2020.07.18.210385 — microbiology — Posted on 2020-07-18
2141 Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
Castaneda-Zegarra, S.; Zhang, Q.; Alirezaylavasani, A.; Fernandez-Berrocal, M.; Yao, R.; Oksenych, V.
10.1101/2020.03.04.976829 — immunology — Posted on 2020-07-18
2145 The landscape of SARS-CoV-2 RNA modifications
Miladi, M.; Fuchs, J.; Maier, W.; Weigang, S.; Diaz i Pedrosa, N.; Weiss, L.; Lother, A.; Nekrutenko, A.; Ruzsics, Z.; Panning, M.; Kochs, G.; Gilsbach, R.; Gruening, B. A.
10.1101/2020.07.18.204362 — genetics — Posted on 2020-07-18
2147 Non-parallel transcriptional divergence during parallel adaptation
Fischer, E. K.; Song, Y.; Hughes, K. A.; Zhou, W.; Hoke, K. L.
10.1101/761619 — evolutionary biology — Posted on 2020-07-18
2150 Data structures based on k-mers for querying large collections of sequencing datasets
Marchet, C.; Boucher, C.; Puglisi, S. J.; Medvedev, P.; Salson, M.; Chikhi, R.
10.1101/866756 — bioinformatics — Posted on 2020-07-18
2151 MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data
Cmero, M.; Schmidt, B.; Majewski, I. J.; Ekert, P. G.; Oshlack, A.; Davidson, N. M.
10.1101/2020.06.03.131532 — bioinformatics — Posted on 2020-07-18
2153 Structural basis for the inhibition of the papain-like protease of SARS-CoV-2 by small molecules
Fu, Z.; Huang, B.; Tang, J.; Liu, S.; Liu, M.; Ye, Y.; Liu, Z.; Xiong, Y.; Cao, D.; Li, J.; Niu, X.; Zhou, H.; Zhao, Y. J.; Zhang, G.; Huang, H.
10.1101/2020.07.17.208959 — biochemistry — Posted on 2020-07-18
2154 A cell competition-based drug screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
Tadele, D. S.; Robertson, J. M.; Crispin, R.; Herrera, M. C.; Chlubnova, M.; Piechaczyk, L. I.; Ayuda-Duran, P.; Singh, S. K.; Gedde-Dahl, T.; Floisand, Y.; Skavland, J.; Wesche, J.; Gjertsen, B.-T.; Enserink, J. M.
10.1101/2020.05.16.089755 — cancer biology — Posted on 2020-07-18
2157 Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation
Fontenete, S.; Christensen, J. R.; Martinez-Silgado, A.; Zarzuela, E.; Munoz, J.; Megias, D.; Castellana, D.; Loewe, R.; Perez-Moreno, M.
10.1101/2020.07.17.209338 — cancer biology — Posted on 2020-07-18
2158 Balancing selection of the Intracellular Pathogen Response in natural Caenorhabditis elegans populations
van Sluijs, L.; Bosman, K. J.; Pankok, F.; Blokhina, T.; Riksen, J. A. G.; Snoek, B.; Pijlman, G. P.; Kammenga, J. E.; Sterken, M. G.
10.1101/579151 — genetics — Posted on 2020-07-18
2163 CRISPR RNA-guided integrases for high-efficiency and multiplexed bacterial genome engineering
Vo, P. L. H.; Ronda, C.; Klompe, S. E.; Chen, E. E.; Acree, C.; Wang, H. H.; Sternberg, S. H.
10.1101/2020.07.17.209452 — molecular biology — Posted on 2020-07-18
2164 Extratubular polymerized uromodulin induces leukocyte recruitment and inflammation in vivo
Immler, R.; Lange-Sperandio, B.; Steffen, T.; Beck, H.; Roth, J.; Hupel, G.; Pfister, F.; Popper, B.; Uhl, B.; Mannell, H.; Reichel, C. A.; Vielhauer, V.; Scherberich, J.; Sperandio, M.; Pruenster, M.
10.1101/2020.07.18.206508 — immunology — Posted on 2020-07-18
2167 RNAseq analysis of rodent spaceflight experiments is confounded by sample collection techniques
Polo, S.-H. L.; Saravia-Butler, A. M.; Boyko, V.; Dinh, M. T.; Chen, Y.-C.; Fogle, H.; Reinsch, S. S.; Ray, S.; Chakravarty, K.; Marcu, O.; Chen, R. B.; Costes, S. V.; Galazka, J. M.
10.1101/2020.07.18.209775 — systems biology — Posted on 2020-07-18
2169 Metformin chlorination byproducts in drinking water exhibit marked toxicity to nematode worms, human cells, and mice
Zhang, R.; He, Y.; Yao, L.; Chen, J.; Zhu, S.; Rao, X.; Tang, P.; You, J.; Zhang, L.; Hua, G.; Ju, F.; Wu, L.
10.1101/2020.07.18.209890 — pharmacology and toxicology — Posted on 2020-07-18
2177 Respiratory Syncytial Virus Infections Induce Hypermetabolism in Pediatric Upper Airways
Rezinciuc, S.; Bezavada, L.; Bahadoran, A.; Ingels, J. F.; Kim, Y.-Y.; Cormier, S. A.; Shulkin, B. L.; Smallwood, H. S.
10.1101/2020.07.18.200964 — systems biology — Posted on 2020-07-18
2178 Understanding photothermal interactions will help expand production range and increase genetic diversity of lentil (Lens culinaris Medik.)
Wright, D. M.; Neupane, S.; Heidecker, T.; Haile, T.; Coyne, C. J.; McGee, R.; Udupa, S.; Henkrar, F.; Barilli, E.; Rubiales, D.; Gioia, T.; Logozzo, G.; Marzario, S.; Mehra, R.; Sarker, A.; Dhakal, R.; Anwar, B.; Sarkar, D.; Vandenberg, A.; Bett, K.
10.1101/2020.07.18.207761 — plant biology — Posted on 2020-07-18
2179 A multipass membrane protein interacts with the cGMP-dependent protein kinase to regulate critical calcium signals in malaria parasites
Balestra, A. C.; Koussis, K.; Klages, N.; Howell, S. A.; Flynn, H. R.; Bantscheff, M.; Pasquarello, C.; Perrin, A. J.; Brusini, L.; Arboit, P.; Sanz, O.; Peces-Barba Castano, L.; Withers-Martinez, C.; Hainard, A.; Ghidelli-Disse, S.; Snijders, A. P.; Baker, D. A.; Blackman, M. J.; Brochet, M.
10.1101/2020.07.18.209973 — microbiology — Posted on 2020-07-18
2181 Regulatory roles of 5' UTR and ORF-internal RNAs detected by 3' end mapping
Adams, P. P.; Baniulyte, G.; Esnault, C.; Chegireddy, K.; Singh, N.; Monge, M.; Dale, R. K.; Storz, G.; Wade, J. T.
10.1101/2020.07.18.207399 — microbiology — Posted on 2020-07-18
2182 Disparate effects of metformin on Mycobacterium tuberculosis infection in diabetic and non-diabetic mice
Sathkumara, H.; Hansen, K.; Miranda-Hernandez, S.; Govan, B.; Rush, C.; Henning, L.; Ketheesan, N.; Kupz, A.
10.1101/2020.07.17.209734 — microbiology — Posted on 2020-07-18
2186 Inhibition of CRISPR-Cas12a DNA Targeting by Nucleosomes and Chromatin
Strohkendl, I. J.; Saifuddin, F. A.; Gibson, B. A.; Rosen, M. K.; Russell, R.; Finkelstein, I. J.
10.1101/2020.07.18.210054 — biochemistry — Posted on 2020-07-18
2187 Unpicking the mysterious symbiosis of mycoplasmas in salmonids
Cheaib, B.; Yang, P.; Kazlauskaite, R.; Lindsay, E.; Heys, C.; De Noia, M.; Schaal, P.; Dwyer, T.; Sloan, W.; Zeeshan Ijaz, U.; Llewellyn, M.
10.1101/2020.07.17.209767 — evolutionary biology — Posted on 2020-07-18
2188 Lysozyme resistance in C. difficile is dependent on two peptidoglycan deacetylases
Kaus, G. M.; Snyder, L. F.; Muh, U.; Flores, M. J.; Popham, D. L.; Ellermeier, C. D.
10.1101/2020.07.17.209676 — microbiology — Posted on 2020-07-18
2189 A novel approach for assessing hypoperfusion in stroke using spatial independent component analysis of resting-state fMRI data
Hu, J.-Y.; Kirilina, E.; Nierhaus, T.; Ovadia-Caro, S.; Livne, M.; Villringer, K.; Margulies, D.; Fiebach, J. B.; Villringer, A.; Khalil, A. A.
10.1101/2020.07.17.208058 — neuroscience — Posted on 2020-07-18
2190 SARS-CoV-2 Spike protein hijacks VEGF-A/Neuropilin-1 receptor signaling to induce analgesia
Moutal, A.; Martin, L. F.; Boinon, L.; Gomez, K.; Ran, D.; Zhou, Y.; Stratton, H. J.; Song, C.; Luo, S.; Gonzalez, K. B.; Perez-Miller, S.; Patwardhan, A.; Ibrahim, M.; Khanna, R.
10.1101/2020.07.17.209288 — neuroscience — Posted on 2020-07-18
2191 Neutralization Assay with SARS-CoV-1 and SARS-CoV-2 Spike Pseudotyped Murine Leukemia Virions
Zheng, Y.; Larragoite, E. T.; Lama, J.; Cisneros, I.; Delgado, J. C.; Slev, P.; Rychert, J.; Coiras, M.; Rondina, M.; Spivak, A. M.; Planelles, V.
10.1101/2020.07.17.207563 — microbiology — Posted on 2020-07-18
2192 Interplay of Monocytes and T Lymphocytes in COVID-19 Severity
Padgett, L. E.; Dinh, H. Q.; Chee, S. J.; Olingy, C. E.; Wu, R.; Araujo, D. J.; Vijayanand, P.; Ottensmeier, C. H.; Hedrick, C. C.
10.1101/2020.07.17.209304 — immunology — Posted on 2020-07-18
2195 Untangling the animacy organization of occipitotemporal cortex
Ritchie, J. B.; Zeman, A. A.; Bosmans, J.; Sun, S.; Verhaegen, K.; Op de Beeck, H. P.
10.1101/2020.07.17.206896 — neuroscience — Posted on 2020-07-18
2196 Landscape management for grassland multifunctionality
Neyret, M.; Fischer, M.; Allan, E.; Hoelzel, N.; Klaus, V.; Kleinebecker, T.; Krauss, J.; Le Provost, G.; Peter, S.; Schenk, N.; Simons, N. K.; van der Plas, F.; Binkenstein, J.; Boershig, C.; Jung, K.; Prati, D.; Schaefer, D.; Schaefer, M.; Schoening, I.; Schrumpf, M.; Tschapka, M.; Westphal, C.; Manning, P.
10.1101/2020.07.17.208199 — ecology — Posted on 2020-07-18
2199 Biodiversity and niche partitioning in an anaerobic benzene degrading culture
Melkonian, C.; Fillinger, L.; Atashgahi, S.; Nunes da Rocha, U.; Kuiper, E.; Olivier, B.; Braster, M.; Gottstein, W.; Helmus, R.; Parsons, J.; Smidt, H.; van der Waals, M.; Gerritse, J.; Brandt, B. W.; Molenaar, D.; van Spanning, R.
10.1101/2020.07.17.208124 — ecology — Posted on 2020-07-18
2202 Rapid tolerance to morphine in the myenteric neurons of the small intestine is independent of β-arrestin-2
Muchhala, K. H.; Jacob, J. C.; Alam, I.; Hasan, S.; Khan, A.; Kang, M.; Dewey, W. L.; Akbarali, H. I.
10.1101/2020.07.17.209437 — pharmacology and toxicology — Posted on 2020-07-17
2204 The Argo: A 65,536 channel recording system for high density neural recording in vivo
Sahasrabuddhe, K.; Khan, A. A.; Singh, A. P.; Stern, T. M.; Ng, Y.; Tadic, A.; Orel, P.; LaReau, C.; Pouzzner, D.; Nishimura, K.; Boergens, K. M.; Shivakumar, S.; Hopper, M. S.; Kerr, B.; Hanna, M.-E. S.; Edgington, R. J.; McNamara, I.; Fell, D.; Gao, P.; Babaie-Fishani, A.; Veijalainen, S.; Klekachev, A. V.; Stuckey, A. M.; Luyssaert, B.; Kozai, T. D. Y.; Xie, C.; Gilja, V.; Dierickx, B.; Kong, Y.; Straka, M.; Sohal, H. S.; Angle, M. R.
10.1101/2020.07.17.209403 — neuroscience — Posted on 2020-07-17
2207 An immersive first-person navigation task for abstract knowledge acquisition
Kuhrt, D.; St. John, N. R.; Bellmund, J. L. S.; Kaplan, R.; Doeller, C. F.
10.1101/2020.07.17.208900 — neuroscience — Posted on 2020-07-17
2209 Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes in a 3,552 Japanese whole-genome sequence dataset (3.5KJPNv2)
Tokunaga, H.; Iida, K.; Hozawa, A.; Ogishima, S.; Watanabe, Y.; Shigeta, S.; Shimada, M.; Yamaguchi-Kabata, Y.; Tadaka, S.; Katsuoka, F.; Ito, S.; Kumada, K.; Hamanaka, Y.; Fuse, N.; Kinoshita, K.; Yamamoto, M.; Yaegashi, N.; Yasuda, J.
10.1101/2020.07.17.208454 — genetics — Posted on 2020-07-17
2211 Dynamical Ising model of spatially-coupled ecological oscillators
Nareddy, V. R.; Machta, J.; Abbott, K. C.; Esmaeili, S.; Hastings, A.
10.1101/2020.07.17.209296 — ecology — Posted on 2020-07-17
2212 Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation
Fontenete, S.; Christensen, J. R.; Martinez-Silgado, A.; Zarzuela, E.; Munoz, J.; Megias, D.; Castellana, D.; Loewe, R.; Perez-Moreno, M.
10.1101/2020.07.17.209338 — cancer biology — Posted on 2020-07-17
2213 Haplocheck: Phylogeny-based Contamination Detection in Mitochondrial and Whole-Genome Sequencing Studies
Weissensteiner, H.; Forer, L.; Fendt, L.; Kheirkhah, A.; Salas, A.; Kronenberg, F.; Schoenherr, S.
10.1101/2020.05.06.080952 — bioinformatics — Posted on 2020-07-17
2214 Teleoperation of an ankle-foot prosthesis with a wrist exoskeleton
Welker, C. G.; Chiu, V. L.; Voloshina, A. S.; Collins, S. H.; Okamura, A. M.
10.1101/2020.07.17.209049 — bioengineering — Posted on 2020-07-17
2215 Resveratrol shortens the chronological lifespan of Saccharomyces cerevisiae by a pro-oxidant mechanism
Canedo-Santos, J. C.; Mora-Martinez, I.; Gutierrez-Garcia, I. K.; Ramirez-Romero, M. G.; Madrigal-Perez, L. A.
10.1101/2020.07.17.209411 — biochemistry — Posted on 2020-07-17
2217 The role of alpha power in the suppression of anticipated distractors during verbal working memory
Sghirripa, S.; Graetz, L.; Merkin, A.; Rogasch, N. C.; Ridding, M. C.; Semmler, J. G.; Goldsowrthy, M. R.
10.1101/2020.07.16.207738 — neuroscience — Posted on 2020-07-17
2218 Trans-synaptic assemblies link synaptic vesicles and neuroreceptors
Martinez-Sanchez, A.; Laugks, U.; Kochovski, Z.; Papantoniou, C.; Baumeister, W.; Lucic, V.
10.1101/2020.07.17.208173 — neuroscience — Posted on 2020-07-17
2220 The adaptive potential of the middle domain of yeast Hsp90
Cote-Hammarlof, P. A.; Fragata, I.; Flynn, J.; Zeldovich, K. B.; Bank, C.; Bolon, D. N. A.
10.1101/832022 — evolutionary biology — Posted on 2020-07-17
2228 Leptospira spp. seroprevalence in humans involved in a cross-sectional study in Garissa and Tana River Counties, Kenya
Mutembei, A.; Mutai, F. K.; Mwololo, D.; Muriuki, J.; Obonyo, M.; Kairu-Wanyoike, S. W.; Wainaina, M.; Lindahl, J.; Ontiri, E.; Bukachi, S.; Njeru, I.; Karanja, J.; Grace, D.; Bett, B.
10.1101/2020.07.17.208363 — microbiology — Posted on 2020-07-17
2229 Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence
Scott, J.; Sueiro-Olivares, M.; Thornton, B. P.; Owens, R. A.; Muhamadali, H.; Fortune-Grant, R.; Thomson, D.; Thomas, R.; Hollywood, K.; Doyle, S.; Goodacre, R.; Tabernero, L.; Bignell, E.; Amich, J.
10.1101/2020.06.04.131862 — microbiology — Posted on 2020-07-17
2230 Parthenogenesis in weevils of the tribe Naupactini (Coleoptera, Curculionidae): a Wolbachia-density dependent trait?
Rodriguero, M. S.; da Cruz Cabral, L.; Fernandez Goya, L.; Piccinali, R. V.; Lanteri, A. A.; Confalonieri, V. A.
10.1101/2020.07.17.208447 — microbiology — Posted on 2020-07-17
2231 ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy
Dutta, I.; Dieters-Castator, D.; Papatzimas, J. W.; Medina, A.; Schueler, J.; Derksen, D. J.; Lajoie, G.; Postovit, L. M.; Siegers, G. M.
10.1101/2020.07.17.207472 — immunology — Posted on 2020-07-17
2232 The enrichment of breakpoints in late-replicating chromatin provides novel insights into chromoanagenesis mechanisms
Chatron, N.; Giannuzzi, G.; Rollat-Farnier, P.-A.; Diguet, F.; Porcu, E.; Yammine, T.; Uguen, K.; Bellil, Z.-L.; Lauer Zillhardt, J.; Sorlin, A.; Ader, F.; Afenjar, A.; Andrieux, J.; Bardel, C.; Calpena, E.; Chantot-Bastaraud, S.; Callier, P.; Chelloug, N.; Chopin, E.; Cordier, M.-P.; Dubourg, C.; Faivre, L.; Girard, F.; Heide, S.; Herenger, Y.; Jaillard, S.; Keren, B.; Knight, S. J. L.; Lespinasse, J.; Lohmann, L.; Marle, N.; Maroofian, R.; Masurel-Paulet, A.; Mathieu-Dramard, M.; Metay, C.; Pagnamenta, A. T.; Portnoi, M.-F.; Prieur, F.; Rio, M.; Siffroi, J.-P.; Valence, S.; Taylor, J. C.; Wi
10.1101/2020.07.17.206771 — genomics — Posted on 2020-07-17
2233 CXCR5 gene expression in human lymph node CD8+ T cells is regulated by DNA methylation and nucleosomal occupancy
Ndhlovu, Z. M.; Ogunshola, F. J.; Smidt, W.; Naidoo, A.; Nkosi, T.; Ngubane, T.; Khaba, T.; Baiyegunhi, O. O.; Rasehlo, S.; Jajbhay, I.; Dong, K. L.; Ramsuran, V.; Pansegrouw, J.; Ndungu, T.; Walker, B. D.; Oliveria, T. d.
10.1101/2020.07.17.208470 — genetics — Posted on 2020-07-17
2235 Computational approaches towards reducing contamination in single-cell RNA-seq data
Yousefi, S.; Chen, H.; Ingles, J. F.; McCarty, M. S.; Centeno, A. G.; Chintalapudi, S.; Mulligan, M. K.; Williams, P. A.; John, S. J.; Jones, B. W.; Jablonski, M. M.; Hollingsworth, T.; Geisert, E. E.; Lu, L.; Williams, R. W.
10.1101/2020.07.15.205062 — bioinformatics — Posted on 2020-07-17
2236 The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals
Bastian, F. B.; Roux, J.; Niknejad, A.; Comte, A.; Fonseca Costa, S. S.; Mendes de Farias, T.; Moretti, S.; Parmentier, G.; Rech de Laval, V.; Rosikiewicz, M.; Wollbrett, J.; Echchiki, A.; Gharib, W. H.; Gonzales-Porta, M.; Jarosz, Y.; Laurenczy, B.; Moret, P.; Person, E.; Roelli, P.; Sanjeev, K.; Seppey, M.; Robinson-Rechavi, M.
10.1101/2020.05.28.119560 — bioinformatics — Posted on 2020-07-17
2237 Ratatosk - Hybrid error correction of long reads enables accurate variant calling and assembly
Holley, G.; Beyter, D.; Ingimundardottir, H.; Kristmundsdottir, S.; Eggertsson, H. P.; Halldorsson, B.
10.1101/2020.07.15.204925 — bioinformatics — Posted on 2020-07-17
2240 Ferroportin 3 is a dual-targeted mitochondrial/chloroplast iron exporter necessary for iron homeostasis in Arabidopsis
Kim, L. J.; Tsuyuki, K. M.; Hu, F.; Park, E. Y.; Zhang, J.; Gallegoe Iraheta, J.; Chia, J.-C.; Huang, R.; Tucker, A. E.; Clyne, M.; Castellano, C.; Kim, A.; Chung, D. D.; DaVeiga, C. T.; Parsons, E. M.; Vatamaniuk, O. K.; Jeong, J.
10.1101/2020.07.15.203646 — plant biology — Posted on 2020-07-17
2244 Comparison of SARS-CoV-2 infections among 3 species of non-human primates
Lu, S.; Zhao, Y.; Yu, W.; Yang, Y.; Gao, J.; Wang, J.; Kuang, D.; Yang, M.; Yang, J.; Ma, C.; Xu, J.; Li, H.; Zhao, S.; Li, J.; Wang, H.; Long, H.; Zhou, J.; Luo, F.; Ding, K.; Wu, D.; Zhang, Y.; Dong, Y.; Liu, Y.; Zheng, Y.; Lin, X.; Jiao, L.; Zheng, H.; Dai, Q.; Sun, Q.; Hu, Y.; Ke, C.; Liu, H.; Peng, X.
10.1101/2020.04.08.031807 — microbiology — Posted on 2020-07-17
2245 SARS-CoV-2 RNA shedding in recovered COVID-19 cases and the presence of antibodies against SARS-CoV-2 in recovered COVID-19 cases and close contacts
Chirathaworn, C.; Sripramote, M.; Chalongviriyalert, P.; Jirajariyavej, S.; Kiatpanabhikul, P.; Saiyarin, J.; Soudon, C.; Thienfaidee, O.; Palakawong Na Ayuthaya, T.; Brukesawan, C.; Chaiwanichsiri, D.; Intharasongkroh, D.; Wanlapakorn, N.; Chansaenroj, J.; Puenpa, J.; Yorsaeng, R.; Thitithanyanont, A.; Kitphati, R.; Mungaomklang, A.; Nagavajara, P.; Poovorawan, Y.
10.1101/2020.07.17.208439 — immunology — Posted on 2020-07-17
2247 Diversified agroforestry systems improve carbon footprint and farmers livelihood under limited irrigation conditions
Rathore, S. S.; Shekhawat, K.; Singh, V. S.; Babu, S. B.; Singh, R.; Upadhyay, P.; Bhattacharyya, R.
10.1101/2020.07.17.208405 — ecology — Posted on 2020-07-17
2248 Coffee consumption and risk of breast cancer: a Mendelian Randomization study
Ellingjord-Dale, M.; Papadimitriou, N. P.; Katsoulis, M.; Yee, C.; Dimou, N.; Gill, D.; Aune, D.; Ong, J.-S.; MacGregor, S.; Elsworth, B.; Lewis, S. J.; Martin, R. M.; Riboli, E.; Tsilidis, K. K.
10.1101/2020.07.17.208421 — cancer biology — Posted on 2020-07-17
2249 A single-cell transcriptome atlas of the aging human and macaque retina
Xue, T.; Yi, W.; Lu, y.; Zhong, S.; zhang, m.; Sun, L.; Dong, H.; Wang, M.; Wei, M.; Xie, H.; Qu, H.; Peng, R.; Hong, J.; Yao, Z.; Tong, Y.; Wang, W.; Ma, Q.; Liu, z.; Ma, Y.; Li, S.; Yin, C.; Liu, J.; Ma, C.; Wang, X.; Wu, Q.
10.1101/2020.07.17.207977 — neuroscience — Posted on 2020-07-17
2251 Patients Derived Short-Term Glioma Culture: Identification of Aggressive, Drug Resistant Phenotype
Beevi, S. S.; Verma, V. K.; Panigrahi, M. K.; Bhale, A.; Madigubba, S.; Chowdary, R.; Korabathina, R.; Gopal Reddy, S.
10.1101/2020.06.04.131680 — cancer biology — Posted on 2020-07-17
2252 Modeling the Impact of Lock-down on COVID-19 Spread in Malaysia
Altahir, A. A.; Mathur, N.; Thiruchelvam, L.; Abro, G. E. M.; Radzi, S. S. M.; Dass, S. C.; Gill, B. S.; Sebastian, P.; Zulkifli, S. A.; Asirvadam, V. S.
10.1101/2020.07.17.208371 — bioinformatics — Posted on 2020-07-17
2253 Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV-challenged nonhuman primates
Pons-Faudoa, F. P.; Sizovs, A.; Shelton, K. A.; Momin, Z.; Bushman, L. R.; Xu, J.; Chua, C. Y. X.; Nichols, J. E.; Hawkins, T.; Rooney, J. F.; Marzinke, M. A.; Kimata, J. T.; Anderson, P. L.; Nehete, P. N.; Arduino, R. C.; Ferrari, M.; Sastry, K. J.; Grattoni, A.
10.1101/2020.05.13.091694 — bioengineering — Posted on 2020-07-17
2255 Piezo1 potentially mediates inflammation in balloon-inflated rat brain and its bidirectional mechanosensitivity
Zhang, Y.; Wang, G.; Xie, M.; Lian, L.; Xiong, Y.; Xu, F.; Li, G.; Tang, Z.; Wang, F.; Zhu, S.
10.1101/2020.07.16.207589 — neuroscience — Posted on 2020-07-17
2256 Transcriptional Signatures of Synaptic Vesicle Genes Define Myotonic Dystrophy Type I Neurodegeneration
Jimenez-Marin, A.; Diez, I.; Labayru, G.; Sistiaga, A.; Sepulcre, J.; Lopez de Munain, A.; Cortes, J. M.
10.1101/2020.07.17.208132 — neuroscience — Posted on 2020-07-17
2258 Fibroblast growth factor 9 stimulates neurite outgrowth through NF-kB signaling in striatal cell Huntington's disease models
Yusuf, I. O.; Chen, H.-M.; Cheng, P.-H.; Chang, C.-Y.; Tsai, S.-J.; Chuang, J.-I.; Wu, C.-C.; Huang, B.-M.; Sun, H. S.; Chen, C.-M.; Yang, S.-H.
10.1101/2020.07.17.207837 — neuroscience — Posted on 2020-07-17
2261 Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model
Driouich, J.-S.; Cochin, M.; Lingas, G.; Moureau, G.; Touret, F.; Petit, P.-R.; Piorkowski, G.; Barthelemy, K.; Coutard, B.; Guedj, J.; de Lamballerie, X.; Solas, C.; Nougairede, A.
10.1101/2020.07.07.191775 — microbiology — Posted on 2020-07-17
2262 Interleukin-19 alleviates experimental autoimmune encephalomyelitis by attenuating antigen-presenting cell activation
Horiuchi, H.; Parajuli, B.; Ogawa, Y.; Komiya, H.; Jin, S.; Takahashi, K.; Azuma, Y.-T.; Tanaka, F.; Suzumura, A.; Takeuchi, H.
10.1101/2020.07.15.204826 — immunology — Posted on 2020-07-17
2263 Detecting selection from linked sites using an F-model
Galimberti, M.; Leuenberger, C.; Wolf, B.; Szilagyi, S. M.; Foll, M.; Wegmann, D.
10.1101/737916 — genomics — Posted on 2020-07-17
2264 Age structuring and spatial heterogeneity in prion protein gene (PRNP) polymorphism in white-tailed deer
Chafin, T. K.; Douglas, M. R.; Martin, B. T.; Zbinden, Z. D.; Middaugh, C. R.; Ballard, J. R.; Gray, M. C.; White, D.; Douglas, M. E.
10.1101/2020.07.15.205039 — genetics — Posted on 2020-07-17
2267 Endothelial basement membrane laminins as an environmental cue in monocyte differentiation to macrophages.
Li, L.; Song, J.; Chuquisana, O.; Hannocks, M.-J.; Loismann, S.; Vogl, T.; Roth, J.; Hallmann, R.; Sorokin, L.
10.1101/2020.04.15.043190 — immunology — Posted on 2020-07-17
2269 Choice-selective sequences in cortical inputs to the NAc provide a potential substrate for credit assignment
Parker, N. F.; Baidya, A.; Cox, J.; Haetzel, L.; Zhukovskaya, A.; Murugan, M.; Engelhard, B.; Goldman, M. S.; Witten, I. B.
10.1101/725382 — neuroscience — Posted on 2020-07-17
2271 Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism
McCausland, J. W.; Yang, X.; Squyres, G. R.; Lyu, Z.; Bruce, K. E.; Lamanna, M. M.; Söderström, B. W.; Garner, E. C.; Winkler, M. E.; Xiao, J.; Liu, J.
10.1101/857813 — biophysics — Posted on 2020-07-17
2274 The methyltransferase DOT1L limits activation and the Th1 program in CD4+ T cells during infection and inflammation
Scheer, S.; Bramhall, M.; Runting, J.; Russ, B.; Zaini, A.; Ellemor, J.; Rodrigues, G.; Ng, J.; Zaph, C.
10.1101/821348 — immunology — Posted on 2020-07-17
2275 Social chemical communication determines recovery from L1 arrest via DAF-16 activation
Mata-Cabana, A.; Gómez-Delgado, L.; Romero-Exposito, F. J.; Rodriguez-Palero, M. J.; Artal-Sanz, M.; Olmedo, M.
10.1101/2020.07.17.208066 — developmental biology — Posted on 2020-07-17
2276 H3.1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation
Dong, J.; LeBlanc, C.; Poulet, A.; Mermaz, B.; Villarino, G.; Webb, K. M.; Joly, V.; Mendez, J.; Voigt, P.; Jacob, Y.
10.1101/2020.07.17.209098 — plant biology — Posted on 2020-07-17
2277 Genomic hitchhiking with moisture adaptation patterns stem prickleless in rose
Zhong, M.-C.; Jiang, X.-D.; Yang, G.-Q.; Cui, W.-H.; Suo, Z.-Q.; Wang, W.-J.; Sun, Y.-B.; Wang, D.; Cheng, X.-C.; Li, X.-m.; Dong, X.; Tang, K.-X.; Li, D.-Z.; Hu, J.-Y.
10.1101/2020.07.16.207795 — plant biology — Posted on 2020-07-17
2278 Regeneration of Functional Retinal Ganglion Cells by Neuronal Identity Reprogramming
Liu, H.; Wei, X.; Zhang, Z.; Zeng, H.-h.; Wang, X.-F.; Zhan, W.; Qiao, N.; Chang, Z.; Liu, L.; Fan, C.; Yang, Z.; Li, X.; Yang, Y.
10.1101/2020.07.16.203497 — neuroscience — Posted on 2020-07-17
2280 Neural processing of iterated prisoner's dilemma outcomes indicates next-round choice and speed to reciprocate cooperation
Cervantes Constantino, F.; Garat, S.; Nicolaisen-Sobesky, E.; Paz, V.; Martinez-Montes, E.; Kessel, D.; Cabana, A.; Gradin, V. B.
10.1101/784033 — neuroscience — Posted on 2020-07-17
2283 TRAF6-IRF5 kinetics, TRIF, and biophysical factors drive synergistic innate responses to particle-mediated MPLA-CpG co-presentation
Pradhan, P.; Toy, R.; Jhita, N.; Blanchard, E. L.; Atalis, A.; Pandey, B.; Santangelo, P. J.; Shayakhmetov, D. M.; Roy, K.
10.1101/2020.07.17.207209 — immunology — Posted on 2020-07-17
2284 Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population
Milner, J.; Nguyen, H.; Omilusik, K.; Reina-Campos, M.; Tsai, M.; Toma, C.; Delpoux, A. D.; Boland, B.; Hedrick, S. M.; Chang, J. T.; Goldrath, A. W.
10.1101/2020.07.17.207266 — immunology — Posted on 2020-07-17
2285 Hoxa10 mediates positional memory to govern stem cell function in adult skeletal muscle
Yoshioka, K.; Nagahisa, H.; Miura, F.; Araki, H.; Kamei, Y.; Kitajima, Y.; Seko, D.; Nogami, J.; Tsuchiya, Y.; Okazaki, N.; Yonekura, A.; Ohba, S.; Sumita, Y.; Chiba, K.; Ito, K.; Asahina, I.; Ogawa, Y.; Ito, T.; Ohkawa, Y.; Ono, Y.
10.1101/2020.07.16.207654 — developmental biology — Posted on 2020-07-17
2287 TLR7 and RIG-I dual-adjuvant loaded nanoparticles drive broadened and synergistic responses in dendritic cells and boost cellular immunity in influenza vaccination
Toy, R.; Keenum, M. C.; Pradhan, P.; Phang, K.; Chen, P.; Chukwu, C.; Nguyen, A.; Liu, J.; Jain, S.; Kozlowski, G.; Hosten, J.; Suthar, M.; Roy, K.
10.1101/2020.07.17.207423 — bioengineering — Posted on 2020-07-17
2290 Free-fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
Croze, M. L.; Flisher, M.; Guillaume, A.; Tremblay, C.; Granziera, S.; Noguchi, G. M.; Vivot, K.; Ghislain, J.; Huising, M. O.; Poitout, V.
10.1101/2020.07.17.208637 — physiology — Posted on 2020-07-17
2292 Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue
Karvinen, S. M.; Zhuang, H.; Zhang, X.; Ojanen, X.; Tormakangas, T.; Velagapudi, V.; Alen, M.; Britton, S. L.; Koch, L. M.; Kainulainen, H.; Cheng, S.; Wiklund, P.
10.1101/2020.07.16.207746 — molecular biology — Posted on 2020-07-17
2293 Stromal Heterogeneity in the Proliferative Endometrial Functionalis - A single-cell approach
Queckboerner, S.; von Grothusen, C.; Boggavarapu, N. R.; Davies, L. C.; Gemzell-Danielsson, K.
10.1101/2020.07.17.203844 — molecular biology — Posted on 2020-07-17
2295 Targeted Genome Editing of Bacteria Within Microbial Communities
Rubin, B. E.; Diamond, S.; Cress, B. F.; Crits-Christoph, A.; He, C.; Xu, M.; Zhou, Z.; Smock, D. C.; Tang, K.; Owens, T. K.; Krishnappa, N.; Sachdeva, R.; Deutschbauer, A. M.; Banfield, J. F.; Doudna, J. A.
10.1101/2020.07.17.209189 — microbiology — Posted on 2020-07-17
2297 Mitochondrial STAT3 regulates proliferation of tissue stem cells.
Peron, M.; Meneghetti, G.; Dinarello, A.; Betto, R. M.; Facchinello, N.; Tiso, N.; Martello, G.; Argenton, F.
10.1101/2020.07.17.208264 — developmental biology — Posted on 2020-07-17
2298 The regulatory landscape of Arabidopsis thaliana roots at single-cell resolution
Dorrity, M. W.; Alexandre, C.; Hamm, M.; Vigil, A.-L.; Fields, S.; Queitsch, C.; Cuperus, J.
10.1101/2020.07.17.204792 — genomics — Posted on 2020-07-17
2299 A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of infective endocarditis
Gaytan, M. O.; Singh, A. K.; Woodiga, S. A.; Patel, S. A.; An, S.-S.; Vera Ponce de Leon, A.; McGrath, S.; Miller, A. R.; Bush, J. M.; van der Linden, M.; Magrini, V.; Wilson, R. K.; Kitten, T.; King, S. J.
10.1101/2020.07.17.206995 — microbiology — Posted on 2020-07-17
2300 Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis
Ducimetiere, L.; Lucchiari, G.; Litscher, G.; Nater, M.; Heeb, L.; Nunez, N. G.; Wyss, L.; Burri, D.; Vermeer, M.; Gschwend, J.; Moor, A.; Becher, B.; van den Broek, M.; Tugues, S.
10.1101/2020.07.17.206433 — immunology — Posted on 2020-07-17
2301 Diversity-based enumeration of optimal context-specific metabolic networks
Rodriguez-Mier, P.; Poupin, N.; de Blasio, C.; Le Cam, L.; Jourdan, F.
10.1101/2020.07.17.208918 — bioinformatics — Posted on 2020-07-17
2305 The mechanism of selective kinesin inhibition by kinesin binding protein.
Atherton, J.; Hummel, J. J. A.; Olieric, N.; Locke, J.; Pena, A.; Rosenfeld, S. S.; Steinmetz, M. O.; Hoogenraad, C. C.; Moores, C. A.
10.1101/2020.07.17.208736 — biochemistry — Posted on 2020-07-17
2307 Phosphatidylinositol-3 kinase activity controls survival and stemness of zebrafish hematopoietic stem/progenitor cells
Blokzijl-Franke, S.; Ponsioen, B.; Schulte-Merker, S.; Herbomel, P.; Kissa, K.; Choorapoikayil, S.; den Hertog, J.
10.1101/2020.07.17.208678 — developmental biology — Posted on 2020-07-17
2308 Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors and suggest subtype specificity
Oliveira, A. S.; Ibarra, A. A.; Bermudez, I.; Casalino, L.; Gaieb, Z.; Shoemark, D. K.; Gallagher, T.; Sessions, R. B.; Amaro, R. E.; Mulholland, A. J.
10.1101/2020.07.16.206680 — biochemistry — Posted on 2020-07-17
2309 Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening
Zhu, W.; Xu, M.; Chen, C. Z.; Guo, H.; Shen, M.; Hu, X.; Shinn, P.; Klumpp-Thomas, C.; Michael, S. G.; Zheng, W.
10.1101/2020.07.17.207019 — pharmacology and toxicology — Posted on 2020-07-17
2311 The First Mitotic Division of the Human Embryo is Highly Error-prone
Ford, E.; Currie, C. E.; Taylor, D. M.; Erent, M.; Marston, A.; Hartshorne, G. M.; McAinsh, A. D.
10.1101/2020.07.17.208744 — cell biology — Posted on 2020-07-17
2313 Identification of SARS-CoV2-mediated suppression of NRF2 signaling reveals a potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Olagnier, D.; Farahani, E.; Thyrsted, J.; Cadanet, J. B.; Herengt, A.; Idorn, M.; Hait, A.; Hernaez, B.; Knudsen, A.; Iversen, M. B.; Schilling, M.; Jorgensen, S. E.; Thomsen, M.; Reinert, L.; Lappe, M.; Hoang, H.-D.; Gilchrist, V. H.; Hansen, A.-L.; Ottosen, R.; Gunderstofte, C.; Moller, C.; van der Horst, D.; Peri, S.; Balachandran, S.; Huang, J.; Jakobsen, M.; Svenningsen, E. B.; Poulsen, T. B.; Bartsch, L.; Thielke, A. L.; Luo, Y.; Alain, T.; Rehwinkel, J.; Alcami, A.; Hiscott, J.; Mogensen, T.; Paludan, S. R.; Holm, C. K.
10.1101/2020.07.16.206458 — microbiology — Posted on 2020-07-17
2315 The long non-coding RNA Pax6os1/PAX6-AS1 modulates pancreatic β-cell identity and function.
Lopez-Noriega, L.; Callingham, R. M.; Martinez-sanchez, A.; Pizza, G.; Haberman, N.; Cvetesic, N.; Lenhard, B.; Marchetti, P.; Piemonti, L.; de Koning, E. J. P.; Shapiro, A. M. J.; Johnson, P. R.; Leclerc, I.; Pullen, T. J.; Rutter, G. A.
10.1101/2020.07.17.209015 — cell biology — Posted on 2020-07-17
2318 COVID-19 patients upregulate toll-like receptor 4-mediated inflammatory signaling that mimics bacterial sepsis
Sohn, K. M.; Lee, S.-G.; Kim, H. J.; Cheon, S.; Jeong, H.; Lee, J.; Kim, I. S.; Silwal, P.; Kim, Y. J.; Park, C.; Kim, Y.-S.; Jo, E.-K.
10.1101/2020.07.17.207878 — immunology — Posted on 2020-07-17
2320 Genetic Diversity and Structure of Oryza rufipogon Griff. Populations in the Philippines
Labarosa, S. J.; Sevilla, N. R.; Tabanao, D. A. A.; Baldo, N. B.; Ebuna, H. L. V.; Jamago, J. M.
10.1101/2020.07.17.194829 — ecology — Posted on 2020-07-17
2321 Co-translational targeting of transcripts to endosomes
Popovic, D.; Nijenhuis, W.; Kapitain, L. C.; Pelkmans, L.
10.1101/2020.07.17.208652 — cell biology — Posted on 2020-07-17
2322 Integrator is a genome-wide attenuator of non-productive transcription
Lykke-Andersen, S.; Zumer, K.; Molska, E. S.; Wu, G.; Rouviere, J. O.; Demel, C.; Schwalb, B.; Schmid, M.; Cramer, P.; Jensen, T. H.
10.1101/2020.07.17.208702 — cell biology — Posted on 2020-07-17
2325 Systematic modeling of SARS-CoV-2 protein structures
O'Donoghue, S. I.; Schafferhans, A.; Sikta, N.; Stolte, C.; Kaur, S.; Ho, B.; Anderson, S.; Procter, J. B.; Adcock, M.; Dallago, C.; Bordin, N.; Rost, B.
10.1101/2020.07.16.207308 — bioinformatics — Posted on 2020-07-17
2330 Loss of Nupr1 promotes engraftment by tuning the dormancy threshold of hematopoietic stem cell repository via regulating p53-checkpoint pathway
Wang, T.; Xia, C.; Cheng, H.; Weng, Q.; Wang, K.; Dong, Y.; Hao, S.; Dong, F.; Liu, X.; Liu, L.; Geng, Y.; Guan, Y.; Du, J.; Cheng, T.; Wang, J.
10.1101/2020.07.16.205898 — cell biology — Posted on 2020-07-17
2336 Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner.
Eysert, F.; Coulon, A.; Boscher, E.; Vreulx, A.-C.; Flaig, A.; Mendes, T.; Hughes, S.; Grenier-Boley, B.; Hanoulle, X.; Demiautte, F.; Bauer, C.; Marttinen, M.; Takalo, M.; Amouyel, P.; Desai, S.; Pike, I.; Hiltunen, M.; Checler, F.; Farinelli, M.; Delay, C.; Malmanche, N.; Hebert, S.; Dumont, J.; Kilinc, D.; Lambert, J.-C.; Chapuis, J.
10.1101/767194 — neuroscience — Posted on 2020-07-17
2337 Skill acquisition and gaze behavior during laparoscopic surgical simulation
Liu, S.; Donaldson, R.; Subramaniam, A.; Palmer, H.; Champion, C.; Cox, M. L.; Appelbaum, L. G.
10.1101/2020.07.17.206763 — neuroscience — Posted on 2020-07-17
2339 Antifibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis
Li, G.; Lee, C.; Read, A. T.; Wang, K.; Navarro, I.; Cui, J.; Young, K.; Gorijavolu, R.; Sulchek, T.; Kopczynski, C.; Farsiu, S.; Samples, J.; Challa, P.; Ethier, C. R.; Stamer, W. D.
10.1101/2020.07.17.208207 — physiology — Posted on 2020-07-17
2340 Leave no stone unturned: The hidden potential of carbon and nitrogen cycling by novel, highly adapted Thaumarchaeota in the Atacama Desert hyperarid core
Hwang, Y.; Schulze-Makuch, D.; Arens, F. L.; Saenz, J. S.; Adam, P. S.; Bornemann, T. L. V.; Airo, A.; Schloter, M.; Probst, A. J.
10.1101/2020.07.17.208546 — genomics — Posted on 2020-07-17
2347 Vinegar and Its Active Component Acetic Acid Inhibit SARS-CoV-2 Infection In Vitro and Ex Vivo
Pagani, I.; Ghezzi, S.; Clementi, M.; Poli, G.; Bussi, M.; Pianta, L.; Trimarchi, M.; Vicenzi, E.
10.1101/2020.07.08.193193 — microbiology — Posted on 2020-07-17
2348 NetCoMi: Network Construction and Comparison for Microbiome Data in R
Peschel, S.; Müller, C. L.; von Mutius, E.; Boulesteix, A.-L.; Depner, M.
10.1101/2020.07.15.195248 — bioinformatics — Posted on 2020-07-17
2349 Taxonomic classification of strain PO100/5 shows a broader geographic distribution and genetic markers of the recently described Corynebacterium silvaticum
Viana, M. V. C.; Profeta, R.; da Silva, A. L.; Hurtado, R.; Cerqueira, J. C.; Sampaio Ribeiro, B. F.; Almeida, M. O.; Morais-Rodrigues, F.; Oliveira, M.; Tavares, L.; Figueiredo, H.; Wattam, A. R.; Barh, D.; Ghosh, P.; Silva, A.; Azevedo, V.
10.1101/2020.07.17.206599 — genomics — Posted on 2020-07-17
2350 Colormesh: A novel method for quantifying variation in complex color patterns
Valvo, J. J.; Rodd, F. H.; Aponte, J. D.; Daniel, M.; Dwinell, K.; Houle, D.; Hughes, K. A.
10.1101/2020.07.17.205369 — evolutionary biology — Posted on 2020-07-17
2351 Immune profiling of gliomas reveals a connection with Tau function and the tumor vasculature.
Sanchez-Gomez, P.; Sepulveda-Sanchez, J. M.; Cejalvo, T.; Hernandez-Lain, A.; Gargini, R.; Segura-Collar, B.; Mata-Martinez, P.; Herranz, B.; Cantero, D.; Ruano, Y.; Garcia-Perez, D.; Perez-Nunez, A.; Ramos, A.; Martin-Soberon, M. C.
10.1101/2020.07.17.208165 — cancer biology — Posted on 2020-07-17
2353 Artificial intelligence based computational framework for drug-target prioritization and inference of novel repositionable drugs for Alzheimer's disease
Tsuji, S.; Hase, T.; Yachie, A.; Nishino, T.; Ghosh, S.; Kikuchi, M.; Shimokawa, K.; Aburatani, H.; Kitano, H.; Tanaka, H.
10.1101/2020.07.17.208116 — bioinformatics — Posted on 2020-07-17
2363 Characterizing the diverse cells that associate with the developing commissures of the zebrafish forebrain
Schnabl, J.; Litz, M. P. H.; Schneider, C.; PenkoffLidbeck, N.; Bashiruddin, S.; Schwartz, M. S.; Alligood, K.; Barresi, M. J. F.
10.1101/2020.07.16.205153 — developmental biology — Posted on 2020-07-17
2367 Hierarchical motor adaptations negotiate failures during force field learning
Ikegami, T.; Ganesh, G.; Gibo, T. L.; Yoshioka, T.; Osu, R.; Kawato, M.
10.1101/2020.07.16.207084 — neuroscience — Posted on 2020-07-17
2368 The rise of disease ecology
Brandell, E. E.; Becker, D.; Sampson, L.; Forbes, K.
10.1101/2020.07.16.207100 — ecology — Posted on 2020-07-17
2373 Early life nociception is influenced by peripheral growth hormone signaling
Dourson, A. J.; Ford, Z. K.; Green, K. J.; McCrossan, C. E.; Hofmann, M. C.; Hudgins, R. C.; Jankowski, M. P.
10.1101/2020.07.16.206904 — neuroscience — Posted on 2020-07-17
2379 A novel bioinformatics approach to reveal the role of circadian oscillations in AD development
Ji, Z.; Shang, D.; Kim, P.; Yang, M.; Wu, S.; Zhao, W.; Kim, E.; Wirianto, M.; Chen, Z.; Yoo, S.-H.; Zhou, X.
10.1101/2020.07.16.207357 — bioinformatics — Posted on 2020-07-17
2383 ShcA promotes chondrocyte hypertrophic commitment and osteoarthritis in mice through RunX2 nuclear translocation and YAP1 inactivation
Abou-Jaoude, A.; Courtes, M.; Badique, L.; Elhaj Mahmoud, D.; Abboud, C.; Mlih, M.; Justiniano, H.; Lemle, A.; Awan, S.; Terrand, J.; Niemeier, A.; Barbero, A.; Houard, X.; Boucher, P.; Matz, R. L.
10.1101/2020.07.16.206870 — physiology — Posted on 2020-07-17
2384 Loss of integration of brain netwroks after one night of sleep deprivation underlies worsening of attentive functions
Pesoli, M.; Rucco, R.; Liparoti, M.; Lardone, A.; D'Aurizio, G.; Minino, R.; Troisi Lopez, E.; Paccone, A.; Granata, C.; Mandolesi, L.; Sorrentino, G.; Sorrentino, P.
10.1101/2020.07.15.197590 — neuroscience — Posted on 2020-07-17
2386 High-Fiber Diet Restores Maternal Obesity-Induced Cognitive and Social Behavioral Deficits in Offspring via Regulating Gut Microbiota-Metabolites-Brain Axis
Liu, X.; Li, X.; Xia, B.; Jin, X.; Zeng, Z.; Yan, S.; Li, L.; Yuan, S.; Zhao, S.; Dai, X.; Yin, F.; Cadenas, E.; Liu, R. H.; Zhao, B.; Hou, M.; Liu, Z.; Liu, X.
10.1101/2020.07.16.206714 — neuroscience — Posted on 2020-07-17
2390 A pentameric protein ring with novel architecture is required for herpesviral packaging
Didychuk, A. L.; Gates, S. N.; Gardner, M. R.; Strong, L. M.; Martin, A.; Glaunsinger, B. A.
10.1101/2020.07.16.206755 — microbiology — Posted on 2020-07-17
2391 CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations
Leader, A. M.; Grout, J. A.; Chang, C.; Maier, B.; Tabachnikova, A.; Walker, L.; Lansky, A.; LeBerichel, J.; Malissen, N.; Davila, M.; Martin, J.; Magri, G.; Tuballes, K.; Zhoa, Z.; Petralia, F.; Samstein, R.; D'Amore, N. R.; Thurston, G.; Kamphorst, A.; Wolf, A.; Flores, R.; Wang, P.; Beasley, M. B.; Salmon, H.; Rahman, A. H.; Marron, T. U.; Kenigsberg, E.; Merad, M.
10.1101/2020.07.16.207605 — immunology — Posted on 2020-07-17
2393 A series of Orai1 gating checkpoints in transmembrane and cytosolic regions requires clearance for CRAC channel opening/ Clearance and synergy of Orai1 gating checkpoints controls pore opening
Tiffner, A.; Schober, R.; Hoeglinger, C.; Bonhenry, D.; Pandey, S.; Lunz, V.; Sallinger, m.; Frischauf, I.; Fahrner, M.; Lindinger, S.; Maltan, L.; Berlansky, S.; Stadlbauer, M.; Schindl, R.; Ettrich, R.; Romanin, C.; Derler, I.
10.1101/2020.07.16.207183 — biophysics — Posted on 2020-07-17
2397 Mutational dynamics and transmission properties of SARS-CoV-2 superspreading events in Austria
Popa, A.; Genger, J.-W.; Nicholson, M.; Penz, T.; Schmid, D.; Aberle, S. W.; Agerer, B.; Lercher, A.; Endler, L.; Colaco, H.; Smyth, M.; Schuster, M.; Grau, M.; Martinez Jimenez, F.; Pich, O.; Borena, W. T.; Pawelka, E.; Keszei, Z.; Senekowitsch, M.; Laine, J.; Aberle, J.; Redlberger-Fritz, M.; Karolyi, M.; Zoufaly, A.; Maritschnik, S.; Borkovec, M.; Hufnagl, P.; Nairz, M.; Weiss, G.; Wolfinger, M. T.; von Laer, D.; Superti-Furga, G.; Lopez-Bigas, N.; Puchhammer-Stoeckl, E.; Allerberger, F.; Michor, F.; Bock, C.; Bergthaler, A.
10.1101/2020.07.15.204339 — microbiology — Posted on 2020-07-17
2398 Longitudinal analysis of the humoral response to SARS-CoV-2 spike RBD in convalescent plasma donors
Perreault, J.; Tremblay, T.; Fournier, M.-J.; Drouin, M.; Beaudoin-Bussieres, G.; Prevost, J.; Lewin, A.; Begin, P.; Finzi, A.; Bazin, R.
10.1101/2020.07.16.206847 — immunology — Posted on 2020-07-17
2399 Metronomic doses and drug schematic combination response tested within microfluidic models for the treatment of breast cancer cells (JIMT-1).
Rosero, G. I.; Pattarone, G.; Penaherrera, A.; Pilz, J. F.; Bödecker, J.; Lerner, B.; Mertelsmann, R.; Perez, M.; Follo, M.
10.1101/2020.07.16.188748 — cancer biology — Posted on 2020-07-17
2401 A single intranasal dose of chimpanzee adenovirus-vectored vaccine confers sterilizing immunity against SARS-CoV-2 infection
Hassan, A. O.; Kafai, N. M.; Dmitriev, I. P.; Fox, J. M.; Smith, B.; Harvey, I. B.; Chen, R. E.; Winkler, E. S.; Wessel, A. W.; Case, J. B.; Kashentseva, E.; McCune, B. T.; Bailey, A. L.; Zhao, H.; VanBlargan, L. A.; Dai, Y.; Ma, M.; Adams, L. J.; Shrihari, S.; Gralinski, L. E.; Hou, Y. J.; Schaefer, A.; Kim, A. S.; Keeler, S. P.; Weiskopf, D.; Baric, R. S.; Holtzman, M. J.; Fremont, D. H.; Curiel, D. T.; Diamond, M. S.
10.1101/2020.07.16.205088 — microbiology — Posted on 2020-07-17
2402 Mechanical overstimulation causes acute injury followed by fast recovery in lateral-line neuromasts of larval zebrafish
Holmgren, M.; Ravicz, M. E.; Hancock, K. E.; Strelkova, O.; Indzhykulian, A. A.; Warchol, M. E.; Sheets, L.
10.1101/2020.07.15.205492 — neuroscience — Posted on 2020-07-17
2403 Seasonal prevalence and characterization of Shiga toxin-producing Escherichia coli on pork carcasses at three steps of the harvest process at two commercial processing plants in the US
Nastasijevic, I. J.; Schmidt, J. W.; Boskovic, M.; Glisic, M.; Kalchayanand, N.; Shackelford, S. D.; Wheeler, T. L.; Koohmaraie, M.; Bosilevac, J. M.
10.1101/2020.07.15.205773 — microbiology — Posted on 2020-07-17
2406 PartSeg, a Tool for Quantitative Feature Extraction From 3D Microscopy Images for Dummies
Bokota, G.; Sroka, J.; Basu, S.; Das, N.; Trzaskoma, P.; Yushkevich, Y.; Grabowska, A.; Magalska, A.; Plewczynski, D.
10.1101/2020.07.16.206789 — bioinformatics — Posted on 2020-07-17
2407 CRISPR-Cas9-mediated editing of myb28 impairs glucoraphanin accumulation of Brassica oleracea in the field
Neequaye, M.; Stavnstrup, S.; Lawrenson, T.; Hundleby, P.; Troncoso-Rey, P.; Saha, S.; Harwood, W.; Traka, M.; Mithen, R.; Ostergaard, L.
10.1101/2020.07.16.206813 — plant biology — Posted on 2020-07-17
2408 Spelling changes and fluorescent tagging with prime editing vectors for plants
Wang, L.; Kaya, H. B.; Zhang, N.; Rai, R.; Willmann, M. R.; Carpenter, S. C. D.; Read, A. C.; Martin, F.; Fei, Z.; Leach, J. E.; Martin, G. B.; Bogdanove, A. J.
10.1101/2020.07.16.206276 — plant biology — Posted on 2020-07-17
2412 Tau in the brain interstitial fluid is fragmented and seeding-competent
Barini, E.; Plotzky, G.; Mordashova, Y.; Hoppe, J.; Rodriguez-Correa, E.; Julier, S.; LePrieult, F.; Mairhofer, I.; Mezler, M.; Biesinger, S.; Cik, M.; Meinhardt, M. W.; Ercan-Herbst, E.; Ehrnhoefer, D.; Striebinger, A.; Bodie, K.; Klein, C.; Gasparini, L.; Schlegel, K.
10.1101/2020.07.15.205724 — neuroscience — Posted on 2020-07-17
2413 Mass Generation, Neuron Labelling and 3D Imaging of Minibrains
Govindan, S.; Batti, L.; Osterop, S. F.; Stoppini, L.; Roux, A.
10.1101/2020.07.11.198531 — neuroscience — Posted on 2020-07-17
2415 Paracoccidioides genomes reflect high levels of species divergence and little interspecific gene flow
Mavengere, H.; Mattox, K.; Teixeira, M. M.; Sepulveda, V.; Gomez, O.; Hernandez, O.; McEwen-Ochoa, J. G.; Matute, D. R.
10.1101/2020.07.16.204636 — microbiology — Posted on 2020-07-17
2417 The risk of Xylella fastidiosa outbreaks will decrease in the Mediterranean olive-producing regions
Godefroid, M.; Morente, M.; Schartel, T.; Cornara, D.; Purcell, A.; Gallego, D.; moreno lozano, A.; Pereira, J.; Fereres, A.
10.1101/2020.07.16.206474 — ecology — Posted on 2020-07-17
2418 Drone-derived canopy height predicts biomass across non-forest ecosystems globally
Cunliffe, A. M.; Anderson, K.; Boschetti, F.; Graham, H. A.; Brazier, R. E.; Myers-Smith, I. H.; Astor, T.; Boer, M. M.; Calvo, L.; Clark, P. E.; Cramer, M. D.; Encinas-Lara, M. S.; Escarzaga, S. M.; Fernandez-Guisuraga, J. M.; Fisher, A. G.; Gdulov, K.; Gillespie, B. M.; Griebel, A.; Hanan, N. P.; Hanggito, M. S.; Haselberger, S.; Havrilla, C. A.; Heilman, P.; Ji, W.; Karl, J. W.; Kirchhoff, M.; Kraushaar, S.; Lyons, M. B.; Marzolff, I.; Mauritz, M. E.; McIntire, C. D.; Metzen, D.; Mendez-Barroso, L. A.; Power, S. C.; Prosek, J.; Sanz-Ablanedo, E.; Sauer, K. J.; Schulze-Bruninghoff, D.; Simov
10.1101/2020.07.16.206011 — ecology — Posted on 2020-07-17
2423 Empagliflozin inhibits proximal tubule NHE3 activity, preserves GFR and restores euvolemia in non-diabetic heart failure rats
Borges-Junior, F. A.; Silva dos Santos, D.; Benetti, A.; Crajoinas, R. O.; Antonio, E.; Jensen, L.; Caramelli, B.; Malnic, G.; Tucci, P.; Girardi, A. C.
10.1101/2020.07.16.207118 — pharmacology and toxicology — Posted on 2020-07-17
2425 Nef enhances HIV-1 replication and infectivity independently of SERINC3 and SERINC5 in CEM T cells
Ramirez, P. W.; Angerstein, A. A.; Suarez, M.; Vollbrecht, T.; Wallace, J.; O'Connell, R. M.; Guatelli, J.
10.1101/2020.07.15.205757 — microbiology — Posted on 2020-07-17
2426 The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion
Collins, C. R.; Hackett, F.; Howell, S. A.; Snijders, A. P.; Russell, M. R.; Collinson, L. M.; Blackman, M. J.
10.1101/2020.07.15.205732 — microbiology — Posted on 2020-07-17
2428 Psychosocial experiences modulate asthma-associated genes through gene-environment interactions
Resztak, J. A.; Farrell, A. K.; Mair-Meijers, H.; Alazizi, A.; Wen, X.; Wildman, D. E.; Zilioli, S.; Slatcher, R. B.; Pique-Regi, R.; Luca, F.
10.1101/2020.07.16.206912 — genomics — Posted on 2020-07-17
2429 Targeted intragenic demethylation initiates chromatin rewiring for gene activation
Liu, Y. V.; Bassal, M. A.; Lin, Q. X. X.; Wu, C. S.; Kwon, J.; Zhou, Q.; Tan, H. K.; Ebralidze, A. K.; Chai, L.; Benoukraf, T.; Di Ruscio, A.; Tenen, D. G.
10.1101/2020.07.16.205922 — genetics — Posted on 2020-07-17
2432 A Novel Fully Automated MRI-Based Deep Learning Method For Classification Of 1p/19q Co-Deletion Status In Brain Gliomas
Bangalore Yogananda, C. G.; Shah, B. R.; Yu, F. F.; Pinho, M. C.; Nalawade, S. S.; Murugesan, G. K.; Wagner, B. C.; Mickey, B.; Patel, T.; Fei, B.; Madhuranthakam, A. J.; Maldjian, J. A.
10.1101/2020.07.15.204933 — neuroscience — Posted on 2020-07-17
2433 Experimental adaptation of dengue virus 1 to Aedes albopictus mosquitoes by in vivo selection
Bellone, R.; Lequime, S.; Jupille, H.; Goertz, G.; Aubry, F.; Mousson, L.; Piorkowski, G.; Yen, P.-S.; Gabiane, G.; Vazeille, M.; Pijlman, G.; Sakuntabhai, A.; de Lamballerie, X.; Lambrechts, L.; Failloux, A.-B.
10.1101/2020.07.16.206524 — microbiology — Posted on 2020-07-17
2434 Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia
Rivas, J. R.; Alhakeem, S. S.; Liu, Y.; Eckenrode, J. M.; Marti, F.; Collard, J. P.; Zhang, Y.; Shaaban, K. A.; Muthusamy, N.; Hildebrandt, G. C.; Fleischman, R. A.; Chen, L.; Thorson, J. S.; Leggas, M.; Bondada, S.
10.1101/2020.07.15.204560 — immunology — Posted on 2020-07-17
2436 Patient-derived glioblastoma cells (GBM) exhibit distinct biomechanical profiles associated with altered activity in the cytoskeleton regulatory pathway
Foss, A.; Zanoni, M.; So, W. Y.; Jenkins, L. M. M.; Tosatto, L.; Bartolini, D.; Gottesman, M. M.; Tesei, A.; Tanner, K.
10.1101/2020.07.16.207233 — biophysics — Posted on 2020-07-17
2439 Altered bacteria community dominance reduces tolerance to resident fungus and seed to seedling growth performance in maize (Zea mays L. var. DBK 177).
Santos, L. F.; Souta, J. F.; Rocha, L. O.; Soares, C. P.; Santos, M. L. C.; Grativol, C.; Roesch, L. F. W.; Olivares, F. L.
10.1101/2020.07.16.206441 — microbiology — Posted on 2020-07-16
2440 Interleukin-19 alleviates experimental autoimmune encephalomyelitis by attenuating antigen-presenting cell activation
Horiuchi, H.; Parajuli, B.; Ogawa, Y.; Komiya, H.; Shijie, J.; Takahashi, K.; Azuma, Y.-T.; Tanaka, F.; Suzumura, A.; Takeuchi, H.
10.1101/2020.07.15.204826 — immunology — Posted on 2020-07-17
2443 Heritable associations with microbial communities are essential for necrotrophic pathogen resistance
Pogoda, C. S.; Reinert, S.; Talukder, Z. I.; Attia, Z.; Corwin, J. A.; Money, K. L.; Collier-zans, E. C. E.; Underwood, W.; Gulya, T. J.; Quandt, A.; Kane, N. C.; Hulke, B. S.
10.1101/2020.07.16.207597 — ecology — Posted on 2020-07-16
2446 ARPEGGIO: Automated Reproducible Polyploid EpiGenetic GuIdance workflOw
Milosavljevic, S.; Kuo, T.; Decarli, S.; Mohn, L.; Sese, J.; Shimizu, K. K.; Shimizu-Inatsugi, R.; Robinson, M.
10.1101/2020.07.16.206193 — bioinformatics — Posted on 2020-07-16
2448 Single cell characterization of a synthetic bacterial clock with a hybrid feedback loop containing dCas9-sgRNA
Henningsen, J.; Schwarz-Schilling, M.; Leibl, A.; Guttierez, J. A. M.; Sagredo, S.; Simmel, F. C.
10.1101/2020.07.16.206722 — synthetic biology — Posted on 2020-07-16
2449 Chemical and technological characteristics of sugarcane as a function of pelletized organomineral fertilizer with filter cake or sewage sludge sources
Carlos Andre Goncalves, C. A.; Camargo, R.; Sousa, R. T. X.; Soares, N. S.; Oliveira, R. C.; Stanger, M. C.; Lana, R. M. Q.; Lemes, E. M.
10.1101/2020.07.16.206136 — plant biology — Posted on 2020-07-16
2450 Liver inflammation before spinal cord injury worsens neuropathology, hepatic injury, metabolic syndrome and locomotor deficits
Goodus, M. T.; Carson, K. E.; Sauerbeck, A. D.; Dey, P.; Alfredo, A. N.; Popovich, P. G.; Bruno, R. S.; McTigue, D. M.
10.1101/2020.07.15.204578 — neuroscience — Posted on 2020-07-16
2451 Temporally integrated single cell RNA sequencing analysis of controlled and natural primary human DENV-1 infections
Waickman, A.; Friberg, H.; Gromowski, G.; Rutvisuttinunt, W.; Li, T.; Siegfried, H.; Victor, K.; McCracken, M.; Fernandez, S.; Srikiatkhachorn, A.; Ellison, D.; Jarman, R. G.; Thomas, S.; Rothman, A. L.; Endy, T.; Currier, J. R.
10.1101/2020.07.16.206557 — immunology — Posted on 2020-07-16
2452 Multi-modal single cell analysis reveals brain immune landscape plasticity during aging and gut microbiota dysbiosis
Golomb, S. M.; Guldner, I. H.; Zhao, A.; Wang, Q.; Palakurthi, B.; Lopez, J.; Yang, K.; Zhang, S.
10.1101/2020.07.15.205377 — immunology — Posted on 2020-07-16
2455 Asymmetric robustness in the feedback control of the retinoic acid network response to environmental disturbances
Parihar, M.; Bendelac-Kapon, L.; Gur, M.; Belorkar, A.; Achanta, S.; Kinberg, K.; Vadigepalli, R.; Fainsod, A.
10.1101/2020.07.15.203794 — developmental biology — Posted on 2020-07-16
2456 Blood transcriptional module repertoire analysis and visualization using R
Rinchai, D.; Roelands, J.; Hendrickx, W.; Altman, M. C.; Bedognetti, D.; Chaussabel, D.
10.1101/2020.07.16.205963 — bioinformatics — Posted on 2020-07-16
2459 The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans
Al Rifai, O.; Julien, C.; Faubert, D.; Lira-Navarrete, E.; Narimatsu, Y.; Lacombe, J.; Clausen, H.; Ferron, M.
10.1101/2020.07.16.206656 — biochemistry — Posted on 2020-07-16
2462 Multiple spatial codes for navigating 2-D semantic spaces
Vigano, S.; Rubino, V.; Di Soccio, A.; Buiatti, M.; Piazza, M.
10.1101/2020.07.16.205955 — neuroscience — Posted on 2020-07-16
2463 Molecular signatures of cognition and affect
Hansen, J. Y.; Markello, R. D.; Vogel, J. W.; Seidlitz, J.; Bzdok, D.; Misic, B.
10.1101/2020.07.16.203026 — neuroscience — Posted on 2020-07-16
2467 Near-infrared spectroscopy outperforms genomic selection for predicting sugarcane feedstock quality traits
Goncalves, M. T. V.; Morota, G.; Costa, P. M. d. A.; Vidigal, P. M. P.; Barbosa, M. H. P.; peternelli, L. A.
10.1101/2020.07.16.206110 — genomics — Posted on 2020-07-16
2469 Mosaic trisomy of chromosome 1q in human brain tissue associates with unilateral polymicrogyria, very early-onset focal epilepsy, and severe developmental delay
Kobow, K.; Jabari, S.; Pieper, T.; Kudernatsch, M.; Polster, T.; Woermann, F. G.; Kalbhenn, T.; Hamer, H.; Roessler, K.; Muehlebner, A.; Spliet, W. G.; Feucht, M.; Hou, Y.; Stichel, D.; Korshunov, A.; Sahm, F.; Coras, R.; Blumcke, I.; von Deimling, A.
10.1101/2020.07.16.206490 — neuroscience — Posted on 2020-07-16
2471 The essential Porphyromonas gingivalis type IX secretion system component PorZ delivers anionic-lipopolysaccharide to the PorU sortase for transpeptidase processing of cargos
Madej, M.; Nowakowska, Z.; Ksiazek, M.; Lasica, A. M.; Mizgalska, D.; Magdalena, N.; Jacula, A.; Scavenius, C.; Enghild, J. J.; Aduse-Opoku, J.; Curtis, M. A.; Gomis-Rüth, F. X.; Potempa, J.
10.1101/2020.07.16.206169 — microbiology — Posted on 2020-07-16
2473 Prevalence of Hepatitis B Virus (HBV) Basal Core Promoter/Precore region molecular variants among HIV/HBV co-infected and HBV mono-infected patients in Ile-Ife, Nigeria
Osasona, O. G.; Boudarene, L.; Adewale-Fasoro, O.; George, U.; Oguzie, J.; Ariyo, O. E.; Olumade, T. J.; Adeniyi, A.; Adewumi, M. O.; Adeniji, A. J.
10.1101/2020.07.16.206151 — microbiology — Posted on 2020-07-16
2475 New genes involved in Angelman syndrome-like: expanding the genetic spectrum
Aguilera, C.; Gabau, E.; Ramirez-Mallafre, A.; Brun-Gasca, C.; Dominguez-Carral, J.; Delgadillo, V.; Laurie, S.; Derdak, S.; Padilla, N.; de la Cruz, X.; Capdevila, N.; Spataro, N.; Baena, N.; Guitart, M.; Ruiz, A.
10.1101/2020.07.16.206052 — genetics — Posted on 2020-07-16
2476 A spinoparabrachial circuit defined by Tacr1 expression drives pain
Barik, A.; Sathyamurthy, A.; Thompson, J.; Seltzer, M.; Levine, A.; Chesler, A.
10.1101/2020.07.15.205484 — neuroscience — Posted on 2020-07-16
2479 Diffusion Histology Imaging Combining Diffusion Basis Spectrum Imaging (DBSI) and Machine Learning Improves Detection and Classification of Glioblastoma Pathology
Ye, Z.; Price, R. L.; Liu, X.; Lin, J.; Yang, Q.; Sun, P.; Wu, A. T.; Wang, L.; Han, R.; Song, C.; Yang, R.; Gary, S. E.; Mao, D. D.; Wallendorf, M.; Campian, J. L.; Li, J.-S.; Dahiya, S.; Kim, A. H.; Song, S.-K.
10.1101/843367 — neuroscience — Posted on 2020-07-16
2481 Pharmacologically modified pluripotent stem cell-based cancer vaccines with anti-metastatic potential
Heront-Kishi, M.; Asgorava, A.; Desterke, C.; Chaker, D.; de Goer, M. G.; TURHAN, A.; Bennaceur, A.; Griscelli, F.
10.1101/2020.05.27.118471 — cancer biology — Posted on 2020-07-16
2484 Long-term live imaging of epithelial organoids and corresponding multiscale analysis reveal high heterogeneity and identify core regulatory principles
Hof, L.; Moreth, T.; Koch, M.; Liebisch, T.; Kurtz, M.; Tarnick, J.; Lissek, S. M.; Verstegen, M. M.; van der Laan, L. J.; Huch, M.; Matthaeus, F.; Stelzer, E. H.; Pampaloni, F.
10.1101/2020.07.12.199463 — cell biology — Posted on 2020-07-16
2485 Computational analysis of lamin isoform interactions with nuclear pore complexes
Kittisopikul, M.; Shimi, T.; Tatli, M.; Tran, J. R.; Zheng, Y.; Medalia, O.; Jaqaman, K.; Adam, S. A.; Goldman, R. D.
10.1101/2020.04.03.022798 — cell biology — Posted on 2020-07-16
2486 Development of Magnetic Particle Imaging (MPI) for Cell Tracking and Detection
Melo, K. P.; Makela, A. V.; Knier, N. N.; Hamilton, A. M.; Foster, P. J.
10.1101/2020.07.12.197780 — biophysics — Posted on 2020-07-16
2488 Modeling alcoholic liver disease in a human Liver-Chip
Nawroth, J. C.; Petropolis, D. B.; Manatakis, D. V.; Maulana, T. I.; Burchett, G.; Schluender, K.; Witt, A.; Shukla, A.; Hamilton, G.; Seki, E.; Lu, S.; Karalis, K.
10.1101/2020.07.14.203166 — bioengineering — Posted on 2020-07-16
2491 Intergenerational pathogen-induced diapause in C. elegans is modulated by mir-243.
Gabaldon, C.; Legüe, M.; Palominos, M. F.; Verdugo, L.; Gutzwiller, F.; Calixto, A.
10.1101/2020.03.31.019349 — microbiology — Posted on 2020-07-16
2492 A high quality reference genome for the fish pathogen Streptococcus iniae
Alsheikh-Hussain, A. S.; Ben Zakour, N. L.; Forde, B. M.; Silayeva, O.; Barnes, A. C.; Beatson, S. A.
10.1101/2019.12.17.880476 — microbiology — Posted on 2020-07-16
2494 Spatial suppression and sensitivity for motion in schizophrenia
Linares, D.; Amoretti, S.; Marin-Campos, R.; Sousa, A.; Prades, L.; Dalmau, J.; Bernardo, M.; Compte, A.
10.1101/799395 — neuroscience — Posted on 2020-07-16
2497 Mainly on the Plane: Deep Subsurface Bacterial Proteins Bind and Alter Clathrate Structure
Johnson, A. M.; Huard, D. J. E.; Kim, J.; Raut, P.; Dai, S.; Lieberman, R. L.; Glass, J. B.
10.1101/2020.06.15.152181 — microbiology — Posted on 2020-07-16
2498 Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease
Wang, W.; Peng, D.; Baptista, R. P.; Li, Y.; Kissinger, J. C.; Tarleton, R. L.
10.1101/2020.07.15.204479 — microbiology — Posted on 2020-07-16
2499 Groundwater Elusimicrobia are metabolically diverse compared to gut microbiome Elusimicrobia and some have a novel nitrogenase paralog
Meheust, R.; Castelle, C. J.; Matheus Carnevali, P. B.; Farag, I.; He, C.; Chen, L.-X.; Amano, Y.; Hug, L. A.; Banfield, J. F.
10.1101/765248 — microbiology — Posted on 2020-07-16
2500 Cell-type and cytosine context-specific evolution of DNA methylation in the human brain
Jeong, H.; Mendizabal, I.; Berto, S.; Chatterjee, P.; Layman, T.; Usui, N.; Toriumi, K.; Douglas, C.; Singh, D.; Huh, I.; Preuss, T. M.; Konopka, G.; Yi, S. V.
10.1101/2020.07.14.203034 — genomics — Posted on 2020-07-16
2502 Upscaling of In Vivo HR-pQCT Images Enables Accurate Simulations of Human Microstructural Bone Adaptation
Ohs, N.; Tourolle ne Betts, D. C.; Atkins, P. R.; Sebastian, S.; van Rietbergen, B.; Blauth, M.; Christen, P.; Müller, R.
10.1101/2020.05.13.093328 — bioinformatics — Posted on 2020-07-16
2504 Spatial summation of pain increases logarithmically
Adamczyk, W. M.; Manthey, L.; Domeier, C.; Szikszay, T. M.; Luedtke, K.
10.1101/2020.06.30.179556 — physiology — Posted on 2020-07-16
2507 Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence
Scott, J.; Sueiro-Olivares, M.; Thornton, B. P.; Owens, R. A.; Muhamadali, H.; Fortune-Grant, R.; Thomas, R.; Hollywood, K.; Doyle, S.; Goodacre, R.; Tabernero, L.; Bignell, E.; Amich, J.
10.1101/2020.06.04.131862 — microbiology — Posted on 2020-07-16
2509 The influence of object-colour knowledge on emerging object representations in the brain
Teichmann, L.; Quek, G. L.; Robinson, A.; Grootswagers, T.; Carlson, T.; Rich, A.
10.1101/533513 — neuroscience — Posted on 2020-07-16
2511 Timing the origin of eukaryotic cellular complexity with ancient duplications
Vosseberg, J.; van Hooff, J. J. E.; Marcet-Houben, M.; van Vlimmeren, A.; van Wijk, L. M.; Gabaldon, T.; Snel, B.
10.1101/823484 — evolutionary biology — Posted on 2020-07-16
2514 Elucidating essential genes in plant-associated Pseudomonas protegens Pf-5 using transposon insertion sequencing
Fabian, B. K.; Foster, C.; Asher, A. J.; Elbourne, L. D.; Hassan, K. A.; Tetu, S. G.; Paulsen, I. T.
10.1101/2020.07.16.205906 — genomics — Posted on 2020-07-16
2516 Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike
Liu, L.; Wang, P.; Nair, M. S.; Yu, J.; Rapp, M.; Wang, Q.; Luo, Y.; Chan, J. F.-W.; Sahi, V.; Figueroa, A.; Guo, X. V.; Cerutti, G.; Bimela, J.; Gorman, J.; Zhou, T.; Chen, Z.; Yuen, K.-Y.; Kwong, P. D.; Sodroski, J. G.; Yin, M. T.; Sheng, Z.; Huang, Y.; Shapiro, L.; Ho, D. D.
10.1101/2020.06.17.153486 — microbiology — Posted on 2020-07-16
2524 Computational approaches towards reducing contamination in single-cell RNA-seq data
Yousefi, S.; Chen, H.; Ingles, J.; Centeno, A.; Chintalapudi, S.; Mulligan, M.; Jones, B.; Williams, R. W.
10.1101/2020.07.15.205062 — bioinformatics — Posted on 2020-07-16
2525 Keratin 17 regulates nuclear morphology and chromatin organization
Jacob, J. T.; Nair, R. R.; Poll, B. G.; Pineda, C. M.; Hobbs, R. P.; Matunis, M. J.; Coulombe, P. A.
10.1101/2020.07.16.206730 — cell biology — Posted on 2020-07-16
2526 Npac Is a Co-factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse ES Cells
Yu, S.; Li, J.; Ji, G.; Ng, Z. L.; Siew, J.; Lo, W. N.; Ye, Y.; Chew, Y.; Long, Y. C.; Zhang, W.; Guccione, E.; Loh, Y.-H.; Jiang, Z.-H.; Yang, H.; Wu, Q.
10.1101/2020.07.16.205989 — molecular biology — Posted on 2020-07-16
2527 Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes
Gainullina, A.; Huang, L.-H.; Todorov, H.; Kim, K.; Yng, L. S.; Kent, A.; Jia, B.; Seddu, K.; Krchma, K.; Wu, J.; Crozat, K.; Tomasello, E.; Narang, V.; Dress, R.; See, P.; Scott, C.; Gibbings, S.; Bajpai, G.; Desai, J. V.; Maier, B.; This, S.; Wang, P.; Aguilar, S. V.; Poupel, L.; Dussaud, S.; Zhou, T.-A.; Angeli, V.; Blander, J. M.; Choi, K.; Dalod, M.; Dzhagalov, I.; Gautier, E. L.; Jakubzick, C.; Lavine, K.; Lionakis, M. S.; Paidassi, H.; Sieweke, M. H.; Ginhoux, F.; Guilliams, M.; Benoist, C.; Merad, M.; Randolph, G. J.; Sergushichev, A.; Artyomov, M. N.; ImmGen Consortium,
10.1101/2020.07.15.204388 — immunology — Posted on 2020-07-16
2528 Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct
SIMONI, y.; LI, S.; ZHUANG, S.; HEIT, A.; KOO, S.-L.; CHOW, I.-T.; KWOK, W. W.; TAN, I. B.; TAN, D. S. W.; NEWELL, E. W.
10.1101/2020.07.15.204172 — immunology — Posted on 2020-07-16
2529 Age structuring and spatial heterogeneity in prion protein gene (PRNP) polymorphism in white-tailed deer
Chafin, T. K.; Douglas, M. R.; Martin, B. T.; Zbinden, Z. D.; Middaugh, C. R.; Ballard, J. R.; Gray, M. C.; White, D.
10.1101/2020.07.15.205039 — genetics — Posted on 2020-07-16
2530 Temporal patterns of vampire bat rabies and host connectivity in Belize
Becker, D. J.; Broos, A.; Bergner, L. M.; Meza, D. K.; Simmons, N. B.; Fenton, M. B.; Altizer, S.; Streicker, D. G.
10.1101/2020.07.16.204446 — ecology — Posted on 2020-07-16
2531 Query to reference single-cell integration with transfer learning
Lotfollahi, M.; Naghipourfar, M.; Luecken, M. D.; Khajavi, M.; Buttner, M.; Avsec, Z.; V. Misharin, A.; Theis, F. J.
10.1101/2020.07.16.205997 — bioinformatics — Posted on 2020-07-16
2532 Reconstitution of the host holobiont acutely increases bone growth of the gnotobiotic rat
Czernik, P. J.; Golonka, R. M.; Chakraborty, S.; Yeoh, B. S.; Saha, P.; Mell, B.; Tian, Y.; Patterson, A. D.; Joe, B.; Vijay-Kumar, M.; Lecka-Czernik, B.
10.1101/2020.07.15.201657 — physiology — Posted on 2020-07-16
2533 Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern time
von Mentzer, A.; Blackwell, G.; Pickard, D.; Boinett, C. J.; Joffre, E.; Page, A. J.; Svennerholm, A.-M.; Dougan, G.; Sjöling, A.
10.1101/2020.07.16.203430 — genomics — Posted on 2020-07-16
2534 Drone phenotyping and machine learning enable discovery of loci regulating daily floral opening in lettuce
Han, R.; Wong, A. J. Y.; Tang, Z.; Truco, M. J.; Lavelle, D. O.; Kozik, A.; Jin, Y.; Michelmore, R. W.
10.1101/2020.07.16.206953 — genetics — Posted on 2020-07-16
2535 Next generation cytogenetics: genome-imaging enables comprehensive structural variant detection for 100 constitutional chromosomal aberrations in 85 samples
Mantere, T.; Neveling, K.; Pebrel-Richard, C.; Benoist, M.; van der Zande, G.; Kater-Baats, E.; Baatout, I.; van Beek, R.; Yammine, T.; Oorsprong, M.; Olde-Weghuis, D.; Majdali, W.; Vermeulen, S.; Pauper, M.; Lebbar, A.; Stevens-Kroef, M.; Sanlaville, D.; Smeets, D.; Dupont, J. M.; Hoischen, A.; Schluth-Bolard, C.; El Khattabi, L.
10.1101/2020.07.15.205245 — genetics — Posted on 2020-07-16
2539 Red seaweed (Asparagopsis taxiformis) supplementation reduces enteric methane by over 80 percent in beef steers
Roque, B. M.; Venegas, M. E.; Kinley, R.; deNys, R.; Neoh, T. L.; Duarte, T. L.; Yang, X.; Salwen, J.; Kebreab, E.
10.1101/2020.07.15.204958 — systems biology — Posted on 2020-07-16
2543 An ancient deletion in the ABO gene affects the composition of the porcine microbiome by altering intestinal N-acetyl-galactosamine concentrations
Yang, H.; Wu, J.; Huang, X.; Zhou, Y.; Zhang, Y.; Liu, M.; Liu, Q.; Ke, S.; He, M.; Fu, H.; Fang, S.; Xiong, X.; Jiang, H.; Chen, Z.; Wu, Z.; Gong, H.; Tong, X.; Huang, Y.; Ma, J.; Gao, J.; Charlier, C.; Coppieters, W.; Shagam, L.; Zhang, Z.; Ai, H.; Yang, B.; Georges, M.; Chen, C.; Huang, L.
10.1101/2020.07.16.206219 — genetics — Posted on 2020-07-16
2544 Genomic prediction in the wild: A case study in Soay sheep
Ashraf, B.; Hunter, D. C.; Bérénos, C.; Ellis, P. A.; Johnston, S. E.; Pilkington, J. G.; Pemberton, J. M.; Slate, J.
10.1101/2020.07.15.205385 — evolutionary biology — Posted on 2020-07-16
2545 Pseudogene-mediated DNA demethylation leads to oncogene activation
Kwon, J.; Liu, Y. V.; Gao, C.; Bassal, M. A.; Jones, A. I.; Yang, J.; Chen, Z.; Li, Y.; Yang, H.; Chen, L.; Di Ruscio, A.; Tay, Y.; Chai, L.; Tenen, D. G.
10.1101/2020.07.15.205542 — cancer biology — Posted on 2020-07-16
2547 Production of moth sex pheromones for pest control by yeast fermentation
Holkenbrink, C.; Ding, B.-J.; Wang, H.-L.; Dam, M. I.; Petkevicius, K.; Kildegaard, K. R.; Wenning, L.; Sinkwitz, C.; Lorantfy, B.; Koutsoumpeli, E.; Franca, L.; Pires, M.; Bernardi, C.; Urrutia, W.; Mafra-Neto, A.; Ferreira, B. S.; Raptopoulos, D.; Konstantopoulou, M.; Löfstedt, C.; Borodina, I.
10.1101/2020.07.15.205047 — bioengineering — Posted on 2020-07-16
2550 Macroscopic digestive anatomy of ring-tailed lemurs (Lemur catta), including a comparison of frozen and formalin-stored specimens
Clauss, M.; Truempler, J.; Ackermans, N. L.; Kitchener, A. C.; Hantke, G.; Stagegaard, J.; Takano, T.; Shintaku, Y.; Matsuda, I.
10.1101/2020.07.16.206201 — zoology — Posted on 2020-07-16
2551 Ferroportin 3 is a dual-targeted mitochondrial/chloroplast iron exporter necessary for iron homeostasis in Arabidopsis
Kim, L. J.; Tsuyuki, K. M.; Hu, F.; Park, E. Y.; Zhang, J.; Gallegoe Iraheta, J.; Chia, J.-C.; Huang, R.; Tucker, A. E.; Clyne, M.; Castellano, C.; Kim, A.; Chung, D. D.; DaVeiga, C. T.; Parsons, E. M.; Vatamaniuk, O. K.; Jeong, J.
10.1101/2020.07.15.203646 — plant biology — Posted on 2020-07-16
2552 Cytoplasmic aggregation of uranium in human dopaminergic cells after continuous exposure to soluble uranyl at non-cytotoxic concentrations
Carmona, A.; Porcaro, F.; Somogyi, A.; Roudeau, S.; Domart, F.; Medjoubi, K.; Aubert, M.; Isnard, H.; Nonell, A.; Rincel, A.; Paredes, E.; Vidaud, C.; Malard, V.; Bresson, C.; Ortega, R.
10.1101/2020.07.16.205831 — pharmacology and toxicology — Posted on 2020-07-16
2554 BaseQTL: a Bayesian method to detect eQTLs from RNA-seq data with or without genotypes
Vigorito, E.; Lin, W. Y.; Starr, C.; Kirk, P. D.; White, S. R.; Wallace, C.
10.1101/2020.07.16.203851 — genomics — Posted on 2020-07-16
2556 Methylation-Based Age Estimation in a Wild Mouse
Little, T. J.; O'Toole, A. N.; Rambaut, A.; Chandra, T.; Marioni, R.; Pedersen, A. B.
10.1101/2020.07.16.203687 — genetics — Posted on 2020-07-16
2557 Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage
Castro Colabianchi, A. M.; Tavella, B.; Boyadjian Lopez, L. E.; Rubinstein, M.; Franchini, L. F.; Lopez, S. L.
10.1101/2020.07.16.167320 — developmental biology — Posted on 2020-07-16
2558 Coincidence detection of mitogenic signals via cytosolic pH regulates Cyclin D1 expression
Koch, L. M.; Birkeland, E.; Battaglioni, S.; Helle, X.; Meerang, M.; Hiltbrunner, S.; Ibanez, A.; Peter, M.; Curioni, A.; Opitz, I.; Dechant, R.
10.1101/2020.07.15.202333 — cell biology — Posted on 2020-07-16
2559 HiFi-SIM: reconstructing high-fidelity structured illumination microscope images
Wen, G.; li, s.; Wang, L.; Chen, X.; Sun, Z.; Liang, Y.; Jin, X.; Tang, Y.; Li, H.
10.1101/2020.07.16.204875 — biophysics — Posted on 2020-07-16
2560 Rapid Establishment of Tracheal Stenosis in Pigs Using Endotracheal Tube Cuff Overpressure and Electrocautery
Kim, J. H.; Ahn, J. J.; Jegal, Y.; Seo, K. W.; Ra, S. W.; Kang, B. J.; Bae, S.; Park, S. E.; Jung, M. S.; Park, J. I.; Cha, H. J.; Lee, Y.; Lee, T.
10.1101/2020.07.16.199679 — physiology — Posted on 2020-07-16
2562 BiPOLES: a tool for bidirectional dual-color optogenetic control of neurons
Vierock, J.; Rodriguez-Rozada, S.; Pieper, F.; Dieter, A.; Bergs, A.; Zeitzschel, N.; Ahlbeck, J.; Sauter, K.; Gottschalk, A.; Engel, A. K.; Hegemann, P.; Wiegert, J. S.
10.1101/2020.07.15.204347 — neuroscience — Posted on 2020-07-16
2564 An automated, high throughput methodology optimized for quantitative cell-free mitochondrial and nuclear DNA isolation from plasma
Ware, S. A.; Desai, N.; Lopez, M.; Leach, D.; Zhang, Y.; Giordano, L.; Nouraie, M.; Picard, M.; Kaufman, B.
10.1101/2020.07.16.206987 — cell biology — Posted on 2020-07-16
2566 Cryo-EM reveals the complex architecture of dynactin's shoulder and pointed end
Lau, C. K.; O'Reilly, F. J.; Santhanam, B.; Lacey, S. E.; Rappsilber, J.; Carter, A. P.
10.1101/2020.07.16.206359 — molecular biology — Posted on 2020-07-16
2567 Simultaneous Epigenetic Perturbation and Genome Imaging Reveal Distinct Roles of H3K9me3 in Chromatin Architecture and Transcription
Feng, Y.; Wang, Y.; Wang, X.; He, X.; Yang, C.; Naseri, A.; Pederson, T.; Zheng, J.; Zhang, S.; Xiao, X.; Xie, W.; Ma, H.
10.1101/2020.07.15.204719 — molecular biology — Posted on 2020-07-16
2568 NetCoMi: Network Construction and Comparison for Microbiome Data in R
Peschel, S.; MüCller, C. L.; von Mutius, E.; Boulesteix, A.-L.; Depner, M.
10.1101/2020.07.15.195248 — bioinformatics — Posted on 2020-07-16
2572 Cas9 fusions for precision in vivo editing
Richardson, R. R.; Steyert, M.; Inen, J.; Khim, S.; Romanowski, A. J.; Altas, B.; Poulopoulos, A.
10.1101/2020.07.15.199620 — synthetic biology — Posted on 2020-07-16
2573 Precise transcriptional control of cellular quiescence by BRAVO/WOX5 complex in Arabidopsis roots
Betegon-Putze, I.; Mercadal, J.; Bosch, N.; Planas-Riverola, A.; Marques-Bueno, M.; Vilarrasa-Blasi, J.; Frigola, D.; Burkart, R. C.; Martinez, C.; Stahl, Y.; Prat, S.; Ibanes, M.; Cano-Delgado, A. I.
10.1101/2020.07.15.203638 — plant biology — Posted on 2020-07-16
2578 Dynamic spatiotemporal coordination of neural stem cell fate decisions through local feedback in the adult vertebrate brain
Dray, N.; Mancini, L.; Binshtok, U.; Cheysson, F.; Supatto, W.; Mahou, P.; Bedu, S.; Ortica, S.; Krecsmarik, M.; Herbert, S.; Masson, J.-B.; Tinevez, J.-Y.; Lang, G.; Beaurepaire, E.; Sprinzak, D.; Bally-Cuif, L.
10.1101/2020.07.15.205021 — neuroscience — Posted on 2020-07-16
2580 Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord
Alkaslasi, M. R.; Piccus, Z. E.; Silberberg, H.; Chen, L.; Zhang, Y.; Petros, T. J.; Le Pichon, C. E.
10.1101/2020.07.16.193292 — neuroscience — Posted on 2020-07-16
2581 Presenilin-deficient neurons and astrocytes display normal mitochondrial phenotypes
Contino, S.; Vrancx, C.; Suelves, N.; Vadukul, D. M.; Payen, V. L.; Stanga, S.; Bertrand, L.; Kienlen-Campard, P.
10.1101/2020.07.15.204255 — neuroscience — Posted on 2020-07-16
2582 Dissociating breathlessness symptoms from mood in asthma
Harrison, O. K.; Marlow, L.; Finnegan, S. L.; Ainsworth, B.; Pattinson, K. T. S.
10.1101/2020.07.15.204289 — neuroscience — Posted on 2020-07-16
2583 Pseudomonas aeruginosa detachment from surfaces via a self-made small molecule
Scheffler, R. J.; Sugimoto, Y.; Bratton, B. P.; Ellison, C. K.; Koch, M. D.; Donia, M. S.; Gitai, Z.
10.1101/2020.07.14.203174 — microbiology — Posted on 2020-07-16
2586 Multi-sample Full-length Transcriptome Analysis of 22 Breast Cancer Clinical Specimens with Long-Read Sequencing
Namba, S.; Ueno, T.; Kojima, S.; Tanaka, Y.; Inoue, S.; Kishigami, F.; Maeda, N.; Ogawa, T.; Hazama, S.; Shiraishi, Y.; Mano, H.; Kawazu, M.
10.1101/2020.07.15.199851 — genomics — Posted on 2020-07-16
2587 Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds
Kowalczyk, I.; Lee, C.; Schuster, E.; Hoeren, J.; Trivigno, V.; Riedel, L.; Goerne, J.; Wallingford, J. B.; Hammes-Lewin, A.; Feistel, K.
10.1101/2020.07.15.205252 — developmental biology — Posted on 2020-07-16
2588 A three-dimensional musculoskeletal model of the dog
Stark, H.; Fischer, M. S.; Hunt, A.; Young, F.; Quinn, R.; Andrada, E.
10.1101/2020.07.16.205856 — bioengineering — Posted on 2020-07-16
2589 Defining the function of OmpA in the Rcs stress response
Letoquart, J.; Dekoninck, K.; Laguri, C.; Demange, P.; Bevernaegie, R.; Simorre, J.-P.; Dehu, O.; Iorga, B. I.; Elias, B.; Cho, S.-H.; Collet, J.-F.
10.1101/2020.07.15.203869 — microbiology — Posted on 2020-07-16
2590 ACDC: Automated Cell Detection and Counting for Time-lapse Fluorescence Microscopy
Rundo, L.; Tangherloni, A.; Tyson, D. R.; Betta, R.; Militello, C.; Spolaor, S.; Nobile, M. S.; Besozzi, D.; Lubbock, A. L. R.; Quaranta, V.; Mauri, G.; Lopez, C. F.; Cazzaniga, P.
10.1101/2020.07.14.202804 — bioinformatics — Posted on 2020-07-16
2594 A common molecular mechanism for cognitive deficits and craving in alcoholism
Meinhardt, M. W.; Pfarr, S.; Rohleder, C.; Vengeliene, V.; Barroso-Flores, J.; Hoffmann, R.; Meinhardt, M. L.; Paul, E.; Hansson, A. C.; Köhr, G.; Meier, N.; von Bohlen und Halbach, O.; Bell, R. L.; Endepols, H.; Neumaier, B.; Schönig, K.; Bartsch, D.; Spanagel, R.; Sommer, W. H.
10.1101/2020.07.13.200519 — neuroscience — Posted on 2020-07-16
2595 Structural engraftment and topographic spacing of transplanted human stem cell-derived retinal ganglion cells
Zhang, K. Y.; Tuffy, C.; Mertz, J. L.; Quillen, S.; Wechsler, L.; Quigley, H. A.; Zack, D. J.; Johnson, T. V.
10.1101/2020.07.14.196055 — neuroscience — Posted on 2020-07-16
2596 Callosal anisotropy predicts attentional network changes after parietal inhibitory stimulation
Schintu, S.; Cunningham, C. A.; Freedberg, M.; Taylor, P.; Gotts, S. J.; Shomstein, S.; Wassermann, E. M.
10.1101/2020.07.13.196824 — neuroscience — Posted on 2020-07-16
2597 SNT: A Unifying Toolbox for Quantification of Neuronal Anatomy
Arshadi, C.; Eddison, M.; Günther, U.; Harrington, K. I. S.; Ferreira, T. A.
10.1101/2020.07.13.179325 — neuroscience — Posted on 2020-07-16
2602 Genetic variants for head size share genes and pathways with cancer
Knol, M. J.; Poot, R. A.; Evans, T. E.; Satizabal, C. L.; Mishra, A.; van der Auwera, S.; Duperron, M.-G.; Jian, X.; Hostettler, I. C.; van Dam-Nolen, D. H. K.; Lamballais, S.; Pawlak, M. A.; Lewis, C. E.; Carrion-Castillo, A.; van Erp, T. G. M.; Reinbold, C. S.; Shin, J.; Scholz, M.; Haberg, A. K.; Kämpe, A.; Li, G. H. Y.; Avinun, R.; Atkins, J. R.; Hsu, F.-C.; Amod, A. R.; Lam, M.; Tsuchida, A.; Teunissen, M. W. A.; Beiser, A. S.; Beyer, F.; Bis, J. C.; Bos, D.; Bryan, R. N.; Bülow, R.; Caspers, S.; Catheline, G.; Cecil, C. A. M.; Dalvie, S.; Dartigues, J.-F.; DeCarli, C.; Enlund-Cerullo,
10.1101/2020.07.15.191114 — genomics — Posted on 2020-07-16
2603 The Demographic History of Micro-endemics: Have Rare Species Always Been Rare?
Helmstetter, A. J.; Cable, S.; Rakotonasolo, F.; Rabarijaona, R.; Rakotoarinivo, M.; Eiserhardt, W. L.; Baker, W. J.; Papadopulos, A. S. T.
10.1101/2020.03.10.985853 — evolutionary biology — Posted on 2020-07-16
2604 Modeling alcoholic liver disease in a human Liver-Chip
Nawroth, J. C.; Petropolis, D. B.; Manatakis, D. V.; Maulana, T. I.; Burchett, G.; Schluender, K.; Witt, A.; Shukla, A.; Hamilton, G.; Seki, E.; Lu, S.; Karalis, K.
10.1101/2020.07.14.203166 — bioengineering — Posted on 2020-07-16
2605 Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant
Yurkovetskiy, L.; Wang, X.; Pascal, K. E.; Tompkins-Tinch, C.; Nyalile, T.; Wang, Y.; Baum, A.; Diehl, W. E.; Dauphin, A.; Carbone, C.; Veinotte, K.; Egri, S. B.; Schaffner, S. F.; Lemieux, J. E.; Munro, J.; Rafique, A.; Barve, A.; Sabeti, P. C.; Kyratsous, C.; Dudkina, N.; Shen, K.; Luban, J.
10.1101/2020.07.04.187757 — microbiology — Posted on 2020-07-16
2608 The lupus autoantigen La is an Xist-binding protein involved in Xist folding and cloud formation
Ha, N.; Ding, N.; Hong, R.; Liu, R.; Roca, X.; Luo, Y.; Duan, X.; Wang, X.; Ni, P.; Zhang, L.-F.; Chen, L.
10.1101/2020.03.07.981860 — molecular biology — Posted on 2020-07-15
2610 FAK regulates IL-33 expression via chromatin accessibility and c-Jun
Griffith, B. G. C.; Upstill-Goddard, R.; Brunton, H.; Grimes, G. R.; Biankin, A. V.; Serrels, B.; Byron, A.; Frame, M. C.
10.1101/2020.07.15.177212 — genomics — Posted on 2020-07-16
2614 A structural model of a Ras-Raf signalosome
Mysore, V. P.; Zhou, Z.-W.; Ambrogio, C.; Li, L.; Kapp, J. N.; Lu, C.; Wang, Q.; Tucker, M. R.; Okoro, J. J.; Nagy-Davidescu, G.; Bai, X.; Pluckthun, A.; Janne, P. A.; Westover, K. D.; Shan, Y.; Shaw, D. E.
10.1101/2020.07.15.165266 — molecular biology — Posted on 2020-07-15
2616 A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells
Schmidt, N.; Lareau, C. A.; Keshishian, H.; Melanson, R.; Zimmer, M.; Kirschner, L.; Ade, J.; Werner, S.; Caliskan, N.; Lander, E. S.; Vogel, J.; Carr, S. A.; Bodem, J.; Munschauer, M.
10.1101/2020.07.15.204404 — microbiology — Posted on 2020-07-15
2617 CLAMP and Zelda function together as pioneer transcription factors to promote Drosophila zygotic genome activation
Duan, J. E.; Rieder, L.; Huang, A.; Jordan, W.; Mckenney, M.; Watters, S.; Fawzi, N. L.; Larschan, E.
10.1101/2020.07.15.205054 — genomics — Posted on 2020-07-15
2620 Definition and Signatures of Lung Fibroblast Populations in Development and Fibrosis in Mice and Men
Liu, X.; C. Rowan, S.; Liang, J.; Yao, C.; Huang, G.; Deng, N.; Xie, T.; Wu, D.; Wang, Y.; Burman, A.; Parimon, T.; Borok, Z.; Chen, P.; C. Parks, W.; Hogaboam, C. M.; Weigt, S. S.; Belperio, J.; R. Stripp, B.; W. Noble, P.; Jiang, D.
10.1101/2020.07.15.203141 — cell biology — Posted on 2020-07-15
2622 Collagen (I) homotrimer does not cause bone fragility but potentiates the osteogenesis imperfecta (oim) mutant allele
Lee, K. J.; Rambault, L.; Bou-Gharios, G.; Clegg, P. D.; Akhtar, R.; Czanner, G.; van 't Hof, R. J.; Canty-Laird, E. G.
10.1101/2020.07.13.198283 — physiology — Posted on 2020-07-15
2625 GPR183 regulates interferons and bacterial growth during Mycobacterium tuberculosis infection: interaction with type 2 diabetes and TB disease severity
Bartlett, S.; Gemiarto, A. T.; Ngo, M. D.; Sajiir, H.; Hailu, S.; Sinha, R.; Foo, C. X.; Kleynhans, L.; Tshivhula, H.; Webber, T.; Bielefeldt-Ohmann, H.; West, N. P.; Hiemstra, A. M.; MacDonald, C. E.; von Voss Christensen, L.; Schlesinger, L. S.; Walzl, G.; Rosenkilde, M. M.; Mandrup-Poulsen, T.; Ronacher, K.
10.1101/2020.07.15.203398 — microbiology — Posted on 2020-07-15
2626 Prophylactic and Therapeutic Inhibition of In Vitro SARS-CoV-2 Replication by Oleandrin
Plante, K. S.; Plante, J. A.; Fernandez, D.; Mirchandani, D.; Bopp, N. E.; Aguilar, P. V.; Sastry, K. J.; Newman, R. A.; Weaver, S. C.
10.1101/2020.07.15.203489 — microbiology — Posted on 2020-07-15
2628 Deconstructing biodiversity-ecosystem function relationships: Filtering of macroinvertebrate traits in a large river floodplain
Rideout, N. K.; Compson, Z. G.; Monk, W. A.; Bruce, M. R.; Hajibabaei, M.; Porter, T. M.; Wright, M. T. G.; Baird, D. J.
10.1101/2020.07.15.204008 — ecology — Posted on 2020-07-15
2629 Bridging the gap: Using reservoir ecology and human serosurveys to estimate Lassa virus incidence in West Africa
Basinski, A. J.; Fichet-Calvet, E. J.; Sjodin, A. R.; Varrelman, T. J.; Remien, C.; Layman, N. C.; Bird, B. H.; Wolking, D. J.; Monagin, C.; Ghersi, B. M.; Barry, P. A.; Jarvis, M. A.; Gessler, P. E.; Nuismer, S. L.
10.1101/2020.03.05.979658 — ecology — Posted on 2020-07-15
2631 Modulate Siglec-7 Signaling via in situ Created High-affinity cis-Ligands
Hong, S.; Yu, C.; Shi, Y.; Wang, P.; Chapla, D. G.; Rodrigues, E.; Moremen, K. W.; Paulson, J. C.; Macauley, M. S.; Wu, P.
10.1101/2020.07.15.203125 — biochemistry — Posted on 2020-07-15
2632 Room Temperature Isothermal Colorimetric Padlock Probe Rolling Circle Amplification for Viral RNA Detection
Huang, W.; Hsu, H.; Ting, J.; Su, J.; Fang, M.; Misaki, T.; Chan, D.; Yang, J.; Yeh, T.-Y.; Yang, K.; Chien, V.; Huang, T.; Chen, A.; Wei, C.; Hsu, J.; Clapper, J. C.
10.1101/2020.06.12.128876 — synthetic biology — Posted on 2020-07-15
2634 A footptrint of plant eco-geographic adaptation on the composition of the barley rhizosphere bacterial microbiota
Alegria Terrazas, R.; Balbirnie-Cumming, K.; Morris, J.; Hedley, P.; Russell, J.; Paterson, E.; Baggs, E.; Fridman, E.; Bulgarelli, D.
10.1101/2020.02.11.944140 — plant biology — Posted on 2020-07-15
2641 The blood-brain barrier studied in vitro across species
Thomsen, M. S.; Humle, N.; Hede, E.; Moos, T.; Burkhart, A.; Thomsen, L. B.
10.1101/2020.07.15.204032 — neuroscience — Posted on 2020-07-15
2644 Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical circuit assembly
Xie, Y.; Kuan, A. T.; Wang, W.; Herbert, Z. T.; Mosto, O.; Olukoya, O.; Adam, M. A.; Vu, S.; Kim, M.; Gomez, N.; Tran, D.; Charpentier, C.; Sorour, I.; Tolstorukov, M. Y.; Sabatini, B. L.; Lee, W.-C. A.; Harwell, C.
10.1101/2020.07.15.204263 — neuroscience — Posted on 2020-07-15
2645 ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain
Lim, J.; Chu, Y.-C.; Hao, C.-M.; Liao, W.-H.; Lin, S.-S.; Hsu, S.; Tai, H.-H.; Chien, Y.-C.; Lai, D.-M.; Chen, W.-S.; Chen, C.-C.; Wang, J.-L.
10.1101/2020.07.10.196634 — neuroscience — Posted on 2020-07-15
2646 Perturbation of in vivo neural activity following α-Synuclein seeding in the olfactory bulb
Kulkarni, A. S.; Cortijo, M. d. M.; Roberts, E. R.; Suggs, T. L.; Stover, H. B.; Pena-Bravo, J. I.; Steiner, J. A.; Luk, K. C.; Brundin, P.; Wesson, D. W.
10.1101/2020.04.17.045013 — neuroscience — Posted on 2020-07-15
2647 Long-range coordination patterns in cortex change withbehavioral context
Dahmen, D.; Layer, M.; Deutz, L.; Dabrowska, P. A.; Voges, N.; von Papen, M.; Brochier, T.; Riehle, A.; Diesmann, M.; Grün, S.; Helias, M.
10.1101/2020.07.15.205013 — neuroscience — Posted on 2020-07-15
2649 Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system
Cantuti-Castelvetri, L.; Ohja, R.; Pedro, L.; Djannatian, M.; Franz, J.; Kuivanen, S.; Kallio, K.; Kaya, T.; Anastasina, M.; Smura, T.; Levanov, L.; Szirovicza, L.; Tobi, A.; Kallio-Kokko, H.; Osterlund, P.; Joensuu, M.; Meunier, F.; Butcher, S.; Winkler, M.; Mollenhauer, B.; Helenius, A.; Gokce, O.; Teesalu, T.; Hepojoki, J.; Vapalahti, O.; Stadelmann, C.; Balistreri, G.; Simons, M.
10.1101/2020.06.07.137802 — microbiology — Posted on 2020-07-15
2650 Transcriptome analysis of sevoflurane exposure effects at the different brain regions
Yamamoto, H.; Uchida, Y.; Chiba, T.; Kurimoto, R.; Matsushima, T.; Ishikawa, C.; Li, H.; Shiga, T.; Muratani, M.; Uchida, T.; Asahara, H.
10.1101/2020.07.15.204040 — genetics — Posted on 2020-07-15
2653 A rooted phylogeny resolves early bacterial evolution
Coleman, G. A.; Davin, A. A.; Mahendrarajah, T.; Spang, A. A.; Hugenholtz, P.; Szöllosi, G. J.; Williams, T. A.
10.1101/2020.07.15.205187 — evolutionary biology — Posted on 2020-07-15
2654 RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development
Mevel, R.; Steiner, I.; Mason, S.; Galbraith, L.; Patel, R.; Fadlullah, M.; Ahmad, I.; Leung, H. Y.; Oliveira, P.; Blyth, K.; Baena, E.; Lacaud, G.
10.1101/2020.06.19.161604 — developmental biology — Posted on 2020-07-15
2657 Raf promotes dimerization of the Ras G-domain with increased allosteric connections
Packer, M.; Parker, J. A.; Chung, J. K.; Li, Z.; Lee, Y. K.; Cookis, T.; Guterres, H.; Alvarez, S.; Hossain, M. A.; Donnelly, D. P.; Agar, J. N.; Makowski, L.; Buck, M.; Groves, J. T.; Mattos, C.
10.1101/2020.07.15.205070 — biophysics — Posted on 2020-07-15
2658 Minimal system for assembly of SARS-CoV-2 virus like particles
Swann, H.; Sharma, A.; Preece, B.; Peterson, A.; Eldredge, C.; Belnap, D.; Vershinin, M.; Saffarian, S.
10.1101/2020.06.01.128058 — biophysics — Posted on 2020-07-15
2659 Quality control and processing of nascent RNA profiling data
Smith, J. P.; Dutta, A. B.; Sathyan, K. M.; Guertin, M. J.; Sheffield, N. C.
10.1101/2020.02.27.956110 — bioinformatics — Posted on 2020-07-15
2660 Filtering Variables for Supervised Sparse Network Analysis
Towle-Miller, L. M.; Miecznikowski, J. C.; Zhang, F.; Tritchler, D. L.
10.1101/2020.03.12.985077 — bioinformatics — Posted on 2020-07-15
2662 The Effect Of Famotidine On SARS-CoV-2 Proteases And Virus Replication
Loffredo, M.; Lucero, H.; Chen, D.-Y.; O'Connell, A.; Bergqvist, S.; Munawar, A.; Bandara, A.; DeGraef, S.; Weeks, S. D.; Douam, F.; Saeed, M.; Munawar, A. H.
10.1101/2020.07.15.203059 — pharmacology and toxicology — Posted on 2020-07-15
2663 The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response
Phasuk, S.; Pairojana, T.; Suresh, P.; Huang, S.-P.; Pakaprot, N.; Chompoopong, S.; Yang, C.-H.; Chang, H.-K.; Chen, C.-C.; Liu, I.
10.1101/2020.07.10.196477 — neuroscience — Posted on 2020-07-15
2669 Establishment of Reference Intervals of Clinical Chemistry Analytes for the Adult Population in Egypt
Baz, H.; Ichihara, K.; Selim, M.; Awad, A.; Aglan, S.; Ramadan, D.; Hassab, A.; Mansour, L.; Elgaddar, O.
10.1101/2020.07.15.204057 — cell biology — Posted on 2020-07-15
2674 Systematic Engineering of Artificial Metalloenzymes for New-to-Nature Reactions
Vornholt, T.; Christoffel, F.; Pellizzoni, M.; Panke, S.; Ward, T. R.; Jeschek, M.
10.1101/2020.07.15.204206 — synthetic biology — Posted on 2020-07-15
2676 Transcriptome profiling in Indian Cattle revealed novel insights into response to heat stress
Khan, R. I. N.; Sahu, A. R.; Malla, W. A.; Praharaj, M. R.; Hosamani, N.; Kumar, S.; Gupta, S.; Sharma, S.; Saxena, A.; Varshney, A.; Singh, P.; Verma, V.; Kumar, P.; Singh, G.; Pandey, A.; Saxena, S.; Gandham, R. K.; Tiwari, A. K.
10.1101/2020.04.09.031153 — physiology — Posted on 2020-07-15
2677 Deciphering cellular transcriptional alterations in Alzheimer's disease brains
Wang, X.; Mariet, A.; Li, S.; Quicksall, Z. S.; Patel, T. A.; Carnwath, T. P.; Reddy, J. S.; Carrasquillo, M. M.; Lincoln, S. J.; Nguyen, T. T.; Malphrus, K. G.; Dickson, D. W.; Crook, J. E.; Asmann, Y. W.; Ertekin-Taner, N.
10.1101/2020.04.15.041376 — neuroscience — Posted on 2020-07-15
2678 Multiple parietal pathways are associated with rTMS-induced hippocampal network enhancement and episodic memory changes.
Freedberg, M. V.; Cunningham, C.; Fioriti, C. M.; Murillo, J. D.; Reeves, J. A.; Taylor, P. A.; Sarlls, J.; Wassermann, E. M. A.
10.1101/2020.07.09.195172 — neuroscience — Posted on 2020-07-15
2680 An experimentally evolved variant of RsmA confirms its central role in the control of Pseudomonas aeruginosa social motility
Robitaille, S.; Lopez de los Santos, Y.; Groleau, M.-C.; Jean-Pierre, F.; Doucet, N.; Perreault, J.; Deziel, E.
10.1101/2020.07.15.203992 — microbiology — Posted on 2020-07-15
2689 Broad and differential animal ACE2 receptor usage by SARS-CoV-2
Zhao, X.; Chen, D.; Szabla, R.; Zheng, M.; Li, G.; Du, P.; Zheng, S.; Li, X.; Song, C.; Li, R.; Guo, J.-T.; Junop, M.; Zeng, H.; Lin, H.
10.1101/2020.04.19.048710 — microbiology — Posted on 2020-07-15
2691 Multi-influential interactions alters behaviour and cognition through six main biological cascades in Down syndrome mouse models
Herault, Y.; Duchon, A.; Muniz Moreno, M. d. M.; Martin Lorenzo, S.; Silva de Souza, M. P.; Chevalier, C.; Nalesso, V.; Meziane, H.; Loureiro de Sousa, P.; Noblet, V.; Armspach, J.-P.; Brault, V.
10.1101/2020.07.08.193136 — genetics — Posted on 2020-07-15
2692 Evidence of SARS-CoV2 entry protein ACE2 in the human nose and olfactory bulb
Klingenstein, M.; Klingenstein, S.; Neckel, P. H.; Mack, A. F.; Wagner, A. P.; Kleger, A.; Liebau, S.; Milazzo, A.
10.1101/2020.07.15.204602 — cell biology — Posted on 2020-07-15
2693 Active synthesis of collagen (I) homotrimer and matrisomal proteins in Dupuytren's fibrosis
Williamson, K.; Cooper, G.; Lee, K. J.; Beamish, E. L.; Simpson, D.; Carter, A.; Gumbs, J. A.; Cheung, G.; Brown, D.; Pettitt, R.; Comerford, E. J.; Clegg, P. D.; Canty-Laird, E. G.
10.1101/2020.07.13.195107 — cell biology — Posted on 2020-07-15
2697 Adolescent frontal top-down neurons receive heightened local drive to establish adult attentional behavior in mice
Nabel, E. M.; Garkun, Y.; Koike, H.; Sadahiro, M.; Liang, A.; Norman, K. J.; Taccheri, G.; Demars, M.; Im, S.; Caro, K.; Lopez, S.; Bateh, J.; Hof, P. R.; Clem, R.; Morishita, H.
10.1101/2020.05.26.117929 — neuroscience — Posted on 2020-07-15
2698 Rora regulates activated T helper cells during inflammation
Liora, V.; Walker, J. A.; Henriksson, J.; Miao, Z.; Natan, E.; Kar, G.; Clare, S.; Barlow, J. L.; Charidemou, E.; Mamanova, L.; Chen, X.; Proserpio, V.; Pramanik, J.; Woodhouse, S.; Protasio, A. V.; Efremova, M.; Griffin, J.; Berriman, M.; Dougan, G.; Fisher, J.; Marioni, J. C.; McKenzie, A. N.; Teichmann, S. A.
10.1101/709998 — immunology — Posted on 2020-07-15
2702 Scanning SWATH acquisition enables high-throughput proteomics with chromatographic gradients as fast as 30 seconds
Messner, C.; Demichev, V.; Bloomfield, N.; White, M.; Kreidl, M.; Ivosev, G.; Wasim, F.; Zelezniak, A.; Lilley, K.; Tate, S.; Ralser, M.
10.1101/656793 — systems biology — Posted on 2020-07-15
2703 Limits to flow detection in phase contrast MRI
Williamson, N. H.; Komlosh, M. E.; Benjamini, D.; Basser, P. J.
10.1101/2020.03.20.000638 — biophysics — Posted on 2020-07-15
2705 Evaluation of NGS-based approaches for SARS-CoV-2 whole genome characterisation
Charre, C.; Ginevra, C.; Sabatier, M.; Regue, H.; Brun, S.; Burfin, G.; Scholtes, C.; Morfin, F.; Valette, M.; Lina, B.; Bal, A.; Josset, L.
10.1101/2020.07.14.201947 — genomics — Posted on 2020-07-15
2707 The S1 protein of SARS-CoV-2 crosses the blood-brain barrier: Kinetics, distribution, mechanisms, and influence of ApoE genotype, sex, and inflammation
Rhea, E. M.; Logsdon, A. F.; Hansen, K. M.; Williams, L.; Reed, M.; Baumann, K.; Holden, S.; Raber, J.; Banks, W. A.; Erickson, M. A.
10.1101/2020.07.15.205229 — neuroscience — Posted on 2020-07-15
2708 An Antioxidant Enzyme Therapeutic for COVID-19
Qin, M.; Cao, Z.; Wen, J.; Yu, Q.; Liu, C.; Wang, F.; Yang, F.; Li, Y.; Fishbein, G. A.; Yan, S.; Xu, B.; Hou, Y.; Ning, Z.; Nie, K.; Jiang, N.; Liu, Z.; Wu, J.; Yu, Y.; Li, H.; Zheng, H.; Li, J.; Jin, W.; Pan, S.; Wang, S.; Chen, J.; Gan, Z.; He, Z.; Lu, Y.
10.1101/2020.07.15.205211 — biochemistry — Posted on 2020-07-15
2709 Antigenic variation of SARS-CoV-2 in response to immune pressure
Forni, D.; Cagliani, R.; Pontremoli, C.; Mozzi, A.; Pozzoli, U.; Clerici, M.; Sironi, M.
10.1101/2020.07.15.204610 — microbiology — Posted on 2020-07-15
2710 Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization
Wang, B.; Asarnow, D.; Lee, W.-H.; Huang, C.-W.; Faust, B.; Ng, P. M. L.; Ngoh, E. Z. X.; Bohn, M.; Bulkley, D.; Pizzorno, A.; Tan, H. C.; Lee, C. Y.; Minhat, R. A.; Terrier, O.; Soh, M. K.; Teo, F. J.; Yeap, Y. Y. C.; Hu, Y.; Seah, S. G. K.; Maurer-Stroh, S.; Renia, L.; Hanson, B. J.; Rosa-Calatrava, M.; Manglik, A.; Cheng, Y.; Craik, C. S.; Wang, C.-I.
10.1101/2020.07.14.203414 — microbiology — Posted on 2020-07-15
2713 Bioinformatic analysis of shared B and T cell epitopes amongst relevant coronaviruses to human health: Is there cross-protection?
Pacheco-Olvera, D. L.; Saint Remy-Hernandez, S.; Acevedo-Ochoa, E.; Arriaga-Pizano, L.; Cerbulo-Vazquez, A.; Ferat-Osorio, E.; Rivera-Hernandez, T.; Lopez-Macias, C.
10.1101/2020.07.14.202887 — immunology — Posted on 2020-07-15
2714 Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula
Simmons, S. C.; Shepard, R. D.; Gouty, S.; Langlois, L. D.; Cox, B.; Nugent, F. S.
10.1101/2020.07.15.202614 — neuroscience — Posted on 2020-07-15
2715 PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin
Ree, R.; Kind, L.; Kaziales, A.; Varland, S.; Dai, M.; Richter, K.; Drazic, A.; Arnesen, T.
10.1101/2020.07.15.202630 — biochemistry — Posted on 2020-07-15
2717 Inhibition of ITK differentiates GVT and GVHD in allo-HSCT
Karimi, M.; Mammadli, M.; Huang, W.; Harris, R.; Sultana, A.; Cheng, Y.; Tong, W.; Pu, J.; Gentile, T.; Henty-Ridilla, J. L.; Dsouza, S.; Yang, Q.; August, A.; Bah, A.
10.1101/2020.07.15.204693 — immunology — Posted on 2020-07-15
2718 What's left in the tank? Identification of non-ascribed aquarium's coral collections with DNA barcodes as part of an integrated diagnostic approach
Colin, L.; Abed-Navandi, D.; A. Conde, D.; Craggs, J.; da Silva, R.; Janse, M.; Källström, B.; Pearce-Kelly, A.; yesson, C.
10.1101/2020.07.15.202739 — genetics — Posted on 2020-07-15
2720 A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
Scott, D. E.; Francis-Newton, N. J.; Marsh, M. E.; Coyne, A. G.; Fischer, G.; Moschetti, T.; Bayly, A. R.; Sharpe, T. D.; Haas, K.; Barber, L.; Valenzano, C.; Srinivasan, R.; Huggins, D. J.; Ehebauer, M.; Esposito, A.; Pellegrini, L.; Perrior, T.; McKenzie, G.; Blundell, T. L.; Hyvonen, M.; Skidmore, J.; Venkitaraman, A. R.; Abell, C.
10.1101/2020.07.15.200709 — cancer biology — Posted on 2020-07-15
2721 Toward a Monte Carlo Approach to Selecting Climate Variables in MaxEnt: A Case Study Using Cassin's Sparrow (Peucaea cassinii)
Schnase, J. L.; Carroll, M. L.; Gill, R. L.; Tamkin, G. S.; Li, J.; Strong, S. L.; Maxwell, T. P.; Aronne, M. E.
10.1101/2020.07.15.202945 — ecology — Posted on 2020-07-15
2722 TRPM7 is a critical regulator of pancreatic endocrine development and high-fat diet-induced β-cell proliferation.
Altman, M. K.; Schaub, C. M.; Dickerson, M. T.; Dadi, P. K.; Graff, S. M.; Galletta, T. J.; Amarnath, G.; Thorson, A. S.; Gu, G.; Jacobson, D. A.
10.1101/2020.07.15.204974 — developmental biology — Posted on 2020-07-15
2726 Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease
Wang, W.; Peng, D.; Baptista, R. P.; Li, Y.; Kissinger, J. C.; Tarleton, R. L.
10.1101/2020.07.15.204479 — microbiology — Posted on 2020-07-15
2727 Plasticenta: Microplastics in Human Placenta
Ragusa, A.; Svelato, A.; Santacroce, C.; Catalano, P.; Notarstefano, V.; Carnevali, O.; Papa, F.; Rongioletti, M. C. A.; Baiocco, F.; Draghi, S.; D'Amore, E.; Rinaldo, D.; Matta, M.; Giorgini, E.
10.1101/2020.07.15.198325 — ecology — Posted on 2020-07-15
2728 Ratatosk - Hybrid error correction of long reads enables accurate variant calling and assembly
Holley, G.; Beyter, D.; Ingimundardottir, H.; Kristmundsdottir, S.; Eggertsson, H. P.; Halldorsson, B.
10.1101/2020.07.15.204925 — bioinformatics — Posted on 2020-07-15
2729 Erythrocyte-targeted immunomodulatory antigens enabled by in vivo selection of D-peptides
Loftis, A. R.; Zhang, G.; Backlund, C.; Quartararo, A. J.; Pishesha, N.; Schissel, C. K.; Garafola, D.; Loas, A.; Collier, R. J.; Ploegh, H.; Irvine, D. J.; Pentelute, B. L.
10.1101/2020.07.15.203331 — bioengineering — Posted on 2020-07-15
2730 Enrichment-Free Identification of Native Definitive (EnFIND) O-glycoproteome of antibodies in autoimmune diseases
Sun, X.; Cheng, J.; Tian, W.; Gao, X. S.; Guo, J.; Hu, F.; Zhang, H.; Huang, X.; Chen, D. D. Y.; Chen, Y.; Wong, C. C.
10.1101/2020.07.15.204511 — systems biology — Posted on 2020-07-15
2733 Towards genetic modification of plant-parasitic nematodes: delivery of macromolecules to adults and expression of exogenous mRNA in second stage juveniles.
Kranse, O.; Beasley, H.; Adams, S.; Pires da Silva, A.; Bell, C.; Lilley, C.; Urwin, P. E.; Bird, D.; Miska, E. A.; Smant, G.; Gheysen, G.; Jones, J.; Viney, M.; Abad, P.; Maier, T. R.; Baum, T. J.; Siddique, S.; Williamson, V.; Akay, A.; Eves-van den Akker, S.
10.1101/2020.07.15.193052 — genetics — Posted on 2020-07-15
2734 Fruit presence induces polar auxin transport in citrus and olive stem and represses hormone release from the bud
Haim, D.; Shalom, L.; Simhon, Y.; Shlizerman, L.; Kamara, I.; Morozov, M.; Rivero, R. M.; Albacete, A. A. M.; Sadka, A.
10.1101/2020.07.15.203927 — plant biology — Posted on 2020-07-15
2735 Acidosis, Zinc and HMGB1 in Sepsis: A Common Connection Involving Sialoglycan Recognition
Siddiqui, S. S.; Dhar, C.; Sundaramurthy, V.; Sasmal, A.; Yu, H.; Bandala-Sanchez, E.; Li, M.; Zhang, X.; Chen, X.; Harrison, L. C.; Xu, D.; Varki, A.
10.1101/2020.07.15.198010 — immunology — Posted on 2020-07-15
2736 Lithium ameliorates Cornelia de Lange syndrome associated phenotypes in experimental models
Grazioli, P.; Parodi, C.; Mariani, M.; Bottai, D.; Di Fede, E.; Zulueta, A.; Avagliano, L.; Cereda, A.; Tenconi, R.; Wierzba, J.; Adami, R.; Iascone, M.; Ajmone, P. F.; Vaccari, T.; Gervasini, C.; Selicorni, A.; Massa, V.
10.1101/2020.07.15.204628 — genetics — Posted on 2020-07-15
2737 Eleven biosynthetic genes explain the majority of natural variation for carotenoid levels in maize grain
Diepenbrock, C. H.; Ilut, D. C.; Magallanes-Lundback, M.; Kandianis, C. B.; Lipka, A. E.; Bradbury, P. J.; Holland, J. B.; Hamilton, J. P.; Wooldridge, E.; Vaillancourt, B.; Gongora-Castillo, E.; Wallace, J. G.; Cepela, J.; Mateos-Hernandez, M.; Owens, B. F.; Tiede, T.; Buckler, E. S.; Rocheford, T.; Buell, C. R.; Gore, M. A.; DellaPenna, D.
10.1101/2020.07.15.203448 — genetics — Posted on 2020-07-15
2740 Vaccinia virus hijacks ESCRT-mediated multivesicular body formation for virus egress
Huttunen, M.; Yakimovich, A.; White, I. J.; Kriston-Vizi, J.; Martin-Serrano, J.; Sundquist, W. I.; Mercer, J.
10.1101/2020.07.15.203935 — cell biology — Posted on 2020-07-15
2747 Biodiversity and Antimicrobial Potential of Bacterial Endophytes from Halophyte Salicornia brachiata
Singh, S.; Ghadge, V.; Kumar, P.; Mathew, D. E.; Dhimmar, A.; Sahastrabudhe, H.; Nalli, Y.; Rathod, M. R.; Shinde, P. B.
10.1101/2020.07.15.203612 — microbiology — Posted on 2020-07-15
2749 Moderate prenatal ethanol exposure increases total length of L1 axons in E15.5 mice
Kiss, S.; Herrera, K.; McElroy, A.; Blake, K.; Sicher, A.; Crocker, E.; Jacob, C.; Lefkove, M.; Cramer, M.; Henriksen, A.; Novacek, J.; Severa, J.; Siberski, J.; Thomas, E.; Favero, C.
10.1101/2020.07.15.204842 — developmental biology — Posted on 2020-07-15
2751 The genetic architecture underlying ecological adaptation in Atlantic herring is not consistent with the infinitesimal model
Han, F.; Jamsandekar, M.; Pettersson, M. E.; Su, L.; Fuentes-Pardo, A.; Davis, B. W.; Bekkevold, D.; Berg, F.; Casini, M.; Dahle, G.; Farrell, E. D.; Folkvord, A.; Andersson, L.
10.1101/2020.07.15.204214 — evolutionary biology — Posted on 2020-07-15
2762 Association of educational attainment polygenic score with school grades in individuals with and without psychiatric disorders.
Rajagopal, V. M.; Trabjerg, B. B.; Grove, J.; Horsdal, H. T.; Petersen, L. V.; Bulik, C.; Bybjerg-Grauholm, J.; Baekvad-Hansen, M.; Hougaard, D. M.; Mors, O.; Nordentoft, M.; Werge, T.; iPSYCH-Broad Consortium, ; Mortensen, P. B.; Agerbo, E.; Borglum, A. D.; Demontis, D.
10.1101/2020.07.15.203661 — genetics — Posted on 2020-07-15
2764 Multi-batch cytometry data integration for optimal immunophenotyping
Ogishi, M.; Yang, R.; Gruber, C.; Pelham, S.; Spaan, A. N.; Rosain, J.; Chbihi, M.; Han, J. E.; Rao, V. K.; Kainulainen, L.; Bustamante, J.; Boisson, B.; Bogunovic, D.; Boisson-Dupuis, S.; Casanova, J.-L.
10.1101/2020.07.14.202432 — bioinformatics — Posted on 2020-07-15
2769 Bacterial quorum sensing signal arrests phytoplankton cell division and protects against virus-induced mortality
Pollara, S. B.; Becker, J. W.; Nunn, B. L.; Boiteau, R.; Repeta, D.; Mudge, M. C.; Downing, G.; Chase, D.; Harvey, E. L.; Whalen, K. E.
10.1101/2020.07.14.202937 — microbiology — Posted on 2020-07-15
2770 Ecogenomics of groundwater viruses suggests niche differentiation linked to specific environmental tolerance
Kothari, A.; Roux, S.; Zhang, H.; Prieto, A.; Soneja, D.; Chandonia, J.-M.; Spencer, S. J.; Wu, X.; Altenburg, S.; Fields, M. W.; Deutschbauer, A. M.; Arkin, A. P.; Alm, E. J.; Chakraborty, R.; Mukhopadhyay, A.
10.1101/2020.07.14.203604 — microbiology — Posted on 2020-07-15
2771 Antibody Escape by Polyomavirus Capsid Mutation Facilitates Neurovirulence
Lauver, M. D.; Goetschius, D. J.; Netherby-Winslow, C. S.; Ayers, K. N.; Jin, G.; Haas, D. G.; Frost, E. L.; Cho, S. H.; Bator, C. M.; Bywaters, S. M.; Christensen, N. D.; Hafenstein, S. L.; Lukacher, A. E.
10.1101/2020.07.14.203281 — immunology — Posted on 2020-07-15
2773 Systematic quantification of health parameters from UK Biobank abdominal MRI using deep learning
Liu, Y.; Basty, N.; Whitcher, B.; Bell, J.; van Bruggen, N.; Thomas, E. L.; Cule, M.
10.1101/2020.07.14.187070 — genetics — Posted on 2020-07-15
2774 Species packing and the latitudinal gradient in local beta-diversity
Cao, K.; Condit, R.; Mi, X.; Chen, L.; Ren, H.; Xu, W.; Burslem, D. F. R. P.; Cai, C.; Cao, M.; Chang, L.-W.; Chu, C.; Cui, F.; Du, H.; Ediriweera, S.; Gunatilleke, C. S. V.; Gunatilleke, I. U. A. N.; Hao, Z.; Jin, G.; Li, J.; Li, B.; Li, Y.; Liu, Y.; Ni, H.; O'Brien, M. J.; Qiao, X.; Shen, G.; Tian, S.; Wang, X.; Xu, H.; Xu, Y.; Yang, L.; Yap, S. L.; Lian, J.; Ye, W.; Yu, M.; Su, S.-H.; Chang-Yang, C.-H.; Guo, Y.; Li, X.; Zeng, F.; Zhu, D.; Zhu, L.; Sun, I.-F.; Ma, K.; Svenning, J.-C.
10.1101/2020.07.14.200006 — ecology — Posted on 2020-07-15
2781 Myeloid deletion and therapeutic activation of AMP-activated protein kinase (AMPK) do not alter atherosclerosis in male or female mice
LeBlond, N. D.; Ghorbani, P.; O'Dwyer, C.; Ambursley, N.; Nunes, J. R.; Smith, T. K.; Trzaskalski, N. A.; Mulvihill, E. E.; Benoit, V.; Foretz, M.; Fullerton, M. D.
10.1101/2020.07.15.204487 — biochemistry — Posted on 2020-07-15
2782 Human saphenous vein provides a unique source of anti-calcific pericytes for prosthetic cardiac valve engineering
Jover, E.; Fagnano, M.; Cathery, W.; Slater, S.; Pisanu, E.; Gu, Y.; Avolio, E.; Bruno, D.; Baz-Lopez, D.; Faulkner, A.; Carrabba, M.; Madeddu, P.
10.1101/2020.07.14.202846 — cell biology — Posted on 2020-07-15
2783 Modeling alcoholic liver disease in a human Liver-Chip
Nawroth, J. C.; Petropolis, D. B.; Manatakis, D. V.; Maulana, T. I.; Burchett, G.; Schluender, K.; Witt, A.; Shukla, A.; Hamilton, G.; Seki, E.; Lu, S.; Karalis, K.
10.1101/2020.07.14.203166 — bioengineering — Posted on 2020-07-15
2784 Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
Ruiz-Vega, R.; Chen, C.-F.; Razzak, E.; Vasudeva, P.; Krasieva, T.; Shiu, J.; Caldwell, M. G.; Yan, H.; Lowengrub, J.; Ganesan, A. K.; Lander, A. D.
10.1101/2020.07.14.203018 — cancer biology — Posted on 2020-07-15
2790 Pharmacokinetics and pharmacodynamics of inhaled antipseudomonal bacteriophage therapy in mice
Chow, M. Y. T.; Chang, R. Y. K.; Li, M.; Wang, Y.; Lin, Y.; Morales, S. P.; McLachlan, A. J.; Kutter, E.; Li, J.; Chan, H. K.
10.1101/2020.07.13.201798 — pharmacology and toxicology — Posted on 2020-07-15
2791 Drug Screening Platform Using Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes and Optical Mapping
Gunawan, M.; Sangha, S.; Shafaattalab, S.; Lin, E.; Heims-Waldron, D.; Bezzerides, V.; Laksman, Z.; Tibbits, G. F.
10.1101/2020.07.14.203232 — pharmacology and toxicology — Posted on 2020-07-15
2793 Cerebral laterality for writing in right- and left-handers: A functional transcranial Doppler ultrasound study
Papadatou-Pastou, M.; Sampanis, P.; Koumzis, I.; Stefanopoulou, S.; Sousani, D.; Tsigkou, A.; Badcock, N. A.
10.1101/2020.07.14.203588 — neuroscience — Posted on 2020-07-15
2795 Fast scanning high optical invariant two-photon microscopy for monitoring a large neural network activity with cellular resolution
Ota, K.; Oisi, Y.; Suzuki, T.; Ikeda, M.; Ito, Y.; Ito, T.; Kobayashi, K.; Kobayashi, M.; Odagawa, M.; Matsubara, C.; Kuroiwa, Y.; Horikoshi, M.; Matsushita, J.; Hioki, H.; Ohkura, M.; Nakai, J.; Oizumi, M.; Miyawaki, A.; Aonishi, T.; Ode, T.; Murayama, M.
10.1101/2020.07.14.201699 — neuroscience — Posted on 2020-07-15
2796 What executive function network is that? An image-based meta-analysis of network labels
Witt, S. T.; van Ettinger-Veenstra, H.; Salo, T.; Riedel, M. C.; Laird, A. R.
10.1101/2020.07.14.201202 — neuroscience — Posted on 2020-07-15
2802 Cerebrospinal fluid (CSF) boosts metabolism and virulence expression factors in Acinetobacter baumannii
Martinez, J.; Razo-Gutierrez, C.; Li, C.; Courville, R.; Pimentel, C.; Liu, C.; Fung, S.; Vila, A. J.; Shahrestani, P.; Jimenez, V.; Tolmasky, M.; Becka, S. A.; Papp-Wallace, K. M.; Bonomo, R. A.; Soler, A.; Sieira, R.; Ramirez, M. S.
10.1101/2020.07.13.201848 — microbiology — Posted on 2020-07-15
2803 Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium
Gandhi, A.; SUN, Z.-Y. J.; KIM, W. M.; Huang, Y.-H.; Kondo, Y.; Bonsor, D. A.; Sundberg, E. J.; Wagner, G.; Kuchroo, V. K.; Petsko, G. A.; Blumberg, R. S.
10.1101/2020.07.14.199711 — immunology — Posted on 2020-07-15
2805 Glutathione S-transferase: A Candidate Gene for Berry Color in Muscadine Grapes (Vitis rotundifolia)
Varanasi, A. V.; Worthington, M. L.; Nelson, L. D.; Brown, A. M.; Threlfall, R. T.; Howard, L. R.; Clark, J.
10.1101/2020.07.14.202903 — genetics — Posted on 2020-07-15
2807 Limits to the cellular control of sequestered cryptophyte prey in the marine ciliate Mesodinium rubrum
Altenburger, A.; Cai, H.; Li, Q.; Drumm, K.; Kim, M.; Zhu, Y.; Garcia-Cuetos, L.; Zhan, X.; Hansen, P. J.; John, U.; Li, S.; Lundholm, N.
10.1101/2020.07.14.202424 — evolutionary biology — Posted on 2020-07-15
2808 Genome analyses reveal the hybrid origin of the staple food crop white Guinea yam
Sugihara, Y.; Darkwa, K.; Yaegashi, H.; Natsume, S.; Shimizu, M.; Abe, A.; Hirabuchi, A.; Ito, K.; Oikawa, K.; Tamiru-Oli, M.; Ohta, A.; Matsumoto, R.; Paterne, A.; De Koeyer, D.; Pachakkil, B.; Yamanaka, S.; Muranaka, S.; Takagi, H.; White, B.; Asiedu, R.; Innan, H.; Asfaw, A.; Adebola, P.; Terauchi, R.
10.1101/2020.07.14.202564 — evolutionary biology — Posted on 2020-07-15
2814 Accurate detection of circulating tumor DNA using nanopore consensus sequencing
Marcozzi, A.; Jager, M.; Elferink, M.; Straver, R.; van Ginkel, J. H.; Peltenburg, B.; Chen, L.-T.; Renkens, I.; van Kuik, J.; Terhaard, C.; de Bree, R.; Devriese, L. A.; Willems, S. M.; Kloosterman, W. P.; de Ridder, J.
10.1101/2020.07.14.202010 — cancer biology — Posted on 2020-07-15
2815 MITF reprograms the extracellular matrix and focal adhesion in melanoma
Dilshat, R.; Fock, V.; Kenny, C.; Gerritsen, I.; Lasseur, R. M. J.; Eichhoff, O.; Travnickova, J.; Cerny, P.; Moller, K.; Sigurbjornsdottir, S.; Kirty, K.; Einarsdottir, B. O.; Cheng, P. F.; Levesque, M.; Cornell, R.; Patton, E. E.; Larue, L.; de Tayrac, M.; Magnusdottir, E.; Ogmundsdottir, M. H.; Steingrimsson, E.
10.1101/2020.07.14.202291 — cancer biology — Posted on 2020-07-15
2816 LC3 subfamily in cardiolipin-mediated mitophagy: A comparison of the LC3A, LC3B and LC3C homologs
Iriondo, M. N.; Etxaniz, A.; Varela, Y. R.; Hervas, J. H.; Montes, L. R.; Goni, F. M.; Alonso, A.
10.1101/2020.07.14.202812 — biophysics — Posted on 2020-07-15
2817 High-density Neural Recordings from Feline Sacral Dorsal Root Ganglia with Thin-film Array
Sperry, Z. J.; Na, K.; Jun, J.; Madden, L. R.; Socha, A.; Yoon, E.; Seymour, J. P.; Bruns, T. M.
10.1101/2020.07.14.199653 — bioengineering — Posted on 2020-07-15
2819 Nuclear GSK-3β and Oncogenic KRas Promote Expansion of Terminal Duct Cells and the Development of Intraductal Papillary Mucinous Neoplasm
Ding, L.; Roeck, K.; Zhang, C.; Zidek, B.; Rodman, E.; Hernandez-Barco, Y. G.; Zhang, J.-S.; Bamlet, W. R.; Oberg, A. L.; Zhang, L.; Bardeesy, N.; Li, H.; Billadeau, D. D.
10.1101/2020.07.14.202952 — cancer biology — Posted on 2020-07-15
2820 Characterization of gene repression by designed transcription activator-like effector dimer proteins
Becker, N.; Peters, J.; Schwab, T.; Phillips, W.; Wallace, J.; Clark, K.; Maher, L. J.
10.1101/2020.07.14.202762 — biophysics — Posted on 2020-07-15
2824 PREDICTIVE IMMUNE CHECKPOINT BLOCKADE CLASSIFIERS DISTINGUISHING MONO- VERSUS COMBINATION THERAPY REQUIREMENT
Krijgsman, O.; Kemper, K.; Boshuizen, J.; Vredevoogd, D. W.; Rozeman, E. A.; Ibanez Molero, S.; de Bruijn, B.; Cornelissen-Steijger, P.; Shahrabi, A.; Del Castillo Velasco-Herrera, M.; Song, J.-Y.; Ligtenberg, M. A.; Kluin, R. J. C.; Kuilman, T.; Ross-MacDonald, P.; Haanen, J.; Adams, D. J.; Blank, C. U.; Peeper, D. S.
10.1101/2020.07.14.202408 — cancer biology — Posted on 2020-07-15
2826 Dynamics in Natural and Designed Elastins and Their Relation to Elastic Fiber Structure and Recoil
Carvajal, M. F. C. A.; Preston, J. M.; Jamhawi, N. M.; Sabo, T. M.; Aramini, J. M.; Wittebort, R. J.; Koder, R.
10.1101/2020.07.14.202523 — biophysics — Posted on 2020-07-15
2827 SmartPeak automates targeted and quantitative metabolomics data processing
Kutuzova, S.; Colaianni, P.; Rost, H.; Sachsenberg, T.; Alka, O.; Kohlbacher, O.; Burla, B.; Torta, F.; Schrubbers, L.; Kristensen, M.; Nielsen, L. K.; Herrgard, M.; McCloskey, D.
10.1101/2020.07.14.202002 — bioinformatics — Posted on 2020-07-15
2829 Modelling the Wolbachia Incompatible Insect Technique: strategies for effective mosquito population elimination
Pagendam, D.; Trewin, B.; Johnson, B. J.; Snoad, N.; Ritchie, S. J.; Hoffmann, A. A.; Staunton, K.; Paton, C.; Beebe, N.
10.1101/2020.07.13.201483 — zoology — Posted on 2020-07-14
2834 The lncRNA APOLO interacts with the transcription factor WRKY42 to trigger root hair cell expansion in response to cold
Moison, M.; Martinez Pacheco, J.; Lucero, L.; Fonouni-Farde, C.; Rodriguez-Melo, J.; Christ, A.; Bazin, J.; Benhamed, M.; Ibanez, F.; Crespi, M.; Estevez, J.; Ariel, F.
10.1101/2020.07.13.188763 — plant biology — Posted on 2020-07-14
2841 SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Clausen, T. M.; Sandoval, D. R.; Spliid, C. B.; Pihl, J.; Painter, C. D.; Thacker, B. E.; Glass, C. A.; Narayanan, A.; Majowicz, S. A.; Zhang, Y.; Torres, J. L.; Golden, G. J.; Porell, R.; Garretson, A. F.; Laubach, L.; Feldman, J.; Yin, X.; Pu, Y.; Hauser, B.; Caradonna, T. M.; Kellman, B. P.; Martino, C.; Gordts, P. L. S. M.; Leibel, S. L.; Chanda, S. K.; Schmidt, A. G.; Godula, K.; Jose, J.; Corbett, K. D.; Ward, A. B.; Carlin, A. F.; Esko, J. D.
10.1101/2020.07.14.201616 — microbiology — Posted on 2020-07-14
2843 An inducible AraC that responds to blue light instead of arabinose
Romano, E.; Baumschlager, A.; Akmeric, E. B.; Palanisamy, N.; Houmani, M.; Schmidt, G.; Oeztuerk, M. A.; Ernst, L.; Khammash, M.; Di Ventura, B.
10.1101/2020.07.14.202911 — microbiology — Posted on 2020-07-14
2848 IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.
Laliotis, G. I.; Chavdoula, E.; Paraskevopoulou, M. D.; Kaba, A.; La Ferlita, A.; Anastas, V.; Orlacchio, A.; Taraslia, V.; Vlachos, I.; Capece, M.; Hatzigeorgiou, A.; Palmieri, D. I.; Alaimo, S.; Tsatsanis, C.; Sehgal, L.; Carbone, D. P.; Coppola, V.; Tsichlis, P. N.
10.1101/2020.07.14.195297 — cancer biology — Posted on 2020-07-15
2849 Peramivir, an anti-influenza virus drug, exhibits potential anti-cytokine storm effects
Su, L.; Wang, Z.; Zhuang, C.; Zhang, C.; Tu, Y.; Kong, D.; Chen, D.; Zhang, W.; Li, Y.
10.1101/2020.07.13.201806 — immunology — Posted on 2020-07-15
2850 Geography is more important than life history in the recent diversification of the tiger salamander complex
Everson, K. M.; Gray, L. N.; Jones, A. G.; Lawrence, N. M.; Foley, M. E.; Sovacool, K. L.; Kratovil, J. D.; Hotaling, S.; Hime, P. M.; Storfer, A.; Parra-Olea, G.; Percino-Daniel, R.; Aguilar-Miguel, X.; O'Neill, E. M.; Zambrano, L.; Shaffer, H. B.; Weisrock, D. W.
10.1101/2020.07.10.197624 — evolutionary biology — Posted on 2020-07-15
2854 Climate change will drive novel cross-species viral transmission
Carlson, C. J.; Albery, G. F.; Merow, C.; Trisos, C. H.; Zipfel, C. M.; Eskew, E. A.; Olival, K.; Ross, N.; Bansal, S.
10.1101/2020.01.24.918755 — ecology — Posted on 2020-07-15
2859 Unbiased placental secretome characterization identifies candidates for pregnancy complications
Napso, T.; Zhao, X.; Ibanez Lligona, M.; Sandovici, I. X.; Kay, R. G.; Gribble, F.; Reimann, F.; Meek, C.; Hamilton, R. S.; Sferruzzi-Perri, A.
10.1101/2020.07.12.198366 — physiology — Posted on 2020-07-14
2860 KHz-rate volumetric voltage imaging of the whole zebrafish heart
Sacconi, L.; Silvestri, L.; Rodriguez, E.; Armstrong, G.; Pavone, F.; Shrier, A.; Bub, G.
10.1101/2020.07.13.196063 — physiology — Posted on 2020-07-14
2861 Collagen (I) homotrimer does not cause bone fragility but potentiates the osteogenesis imperfecta (oim) mutant allele
Lee, K. J.; Rambault, L.; Bou-Gharios, G.; Clegg, P. D.; Akhtar, R.; Czanner, G.; van 't Hof, R. J.; Canty-Laird, E. G.
10.1101/2020.07.13.198283 — physiology — Posted on 2020-07-14
2862 A tropane-based ibogaine analog rescues folding-deficient SERT and DAT
Bhat, S.; Guthrie, D. A.; Kasture, A.; El-Kasaby, A.; Cao, J.; Bonifazi, A.; Ku, T.; Ku, T.; Giancola, J. B.; Hummel, T.; Freissmuth, M.; Newman, A. H.
10.1101/2020.07.14.202325 — pharmacology and toxicology — Posted on 2020-07-14
2863 Accurate recognition of colorectal cancer with semi-supervised deep learning on pathological images
Yu, G.; Xie, T.; Xu, C.; Shi, X.-H.; Wu, C.; Meng, R.-Q.; Meng, X.-H.; Wang, K.-S.; Xiao, H.-M.; Deng, H.-W.
10.1101/2020.07.13.201582 — pathology — Posted on 2020-07-14
2864 A Cretaceous bug with exaggerated antennae might be a double-edged sword in evolution
Du, B.-J.; Chen, R.; Tao, W.-T.; Shi, H.-L.; Bu, W.-J.; Liu, Y.; Ma, S.; Ni, M.-Y.; Kong, F.-L.; Xiao, J.-H.; Huang, D.-W.
10.1101/2020.02.11.942920 — paleontology — Posted on 2020-07-14
2865 Molecular and cellular pathology of monogenic Alzheimer's disease at single cell resolution
Marinaro, F.; Haneklaus, M.; Zhang, Z.; Strano, A.; Evans, L. D.; Handfield, L.-F.; Ryan, N.; Fox, N.; Hemberg, M.; Ramanathan, S.; Livesey, F. J.
10.1101/2020.07.14.202317 — neuroscience — Posted on 2020-07-14
2868 Development of a genetically-encoded oxytocin sensor
Mignocchi, N. L.; Kruessel, S.; Jung, K.; Lee, D.; Kwon, H.-B.
10.1101/2020.07.14.202598 — neuroscience — Posted on 2020-07-14
2871 Syncytia formation by SARS-CoV-2 infected cells
Buchrieser, J.; Dufloo, J.; Hubert, M.; Monel, B.; Planas, D.; Rajah, M. M.; Planchais, C.; Porrot, F.; Guivel-Benhassine, F.; van der Werf, S.; Casartelli, N.; Mouquet, H.; Bruel, T.; Schwartz, O.
10.1101/2020.07.14.202028 — microbiology — Posted on 2020-07-14
2872 Movements of ancient human endogenous retroviruses detected in SOX2-expressing cells
Monde, K.; Satou, Y.; Goto, M.; Uchiyama, Y.; Ito, J.; Kaitsuka, T.; Terasawa, H.; Yamaga, S.; Matsusako, T.; Wei, F. Y.; Inoue, I.; Tomizawa, K.; Ono, A.; Era, T.; Sawa, T.; Maeda, Y.
10.1101/2020.07.14.202135 — microbiology — Posted on 2020-07-14
2873 The antibody response to the glycan α-Gal correlates with COVID-19 disease symptoms
Urra, J. M.; Ferreras-Colino, E.; Contreras, M.; Cabrera, C. M.; Fernandez de Mera, I. G.; Villar, M.; Cabezas-Cruz, A.; Gortazar, C.; de la Fuente, J.
10.1101/2020.07.14.201954 — immunology — Posted on 2020-07-14
2874 PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism
Simula, L.; Cancila, V.; Antonucci, Y.; Colamatteo, A.; Procaccini, C.; Matarese, G.; Tripodo, C.; Campello, S.
10.1101/2020.07.14.200592 — immunology — Posted on 2020-07-14
2877 Cell-type and cytosine context-specific evolution of DNA methylation in the human brain
Jeong, H.; Mendizabal, I.; Berto, S.; Chatterjee, P.; Layman, T.; Usui, N.; Toriumi, K.; Douglas, C.; Singh, D.; Huh, I.; Preuss, T. M.; Konopka, G.; Yi, S. V.
10.1101/2020.07.14.203034 — genomics — Posted on 2020-07-14
2879 A modelling framework for the prediction of the herd-level probability of infection from longitudinal data
Madouasse, A.; Mercat, M.; van Roon, A.; Graham, D.; Guelbenzu, M.; Santman Berends, I.; van Schaik, G.; Nielen, M.; Frössling, J.; Agren, E.; Humphry, R.; Eze, J.; Gunn, G.; Henry, M. K.; Gethmann, J.; More, S. J.; Fourichon, C.
10.1101/2020.07.10.197426 — bioinformatics — Posted on 2020-07-14
2880 Targeting heparan sulfate proteoglycan-assisted endocytosis as a COVID-19 therapeutic option
Zhang, Q.; Chen, C.; Swaroop, M.; Xu, M.; Wang, L.; Lee, J.; Pradhan, M.; Shen, M.; Luo, Z.; Xu, Y.; Huang, W.; Zheng, W.; Ye, Y.
10.1101/2020.07.14.202549 — cell biology — Posted on 2020-07-14
2881 A Chemical-genetics and Nanoparticle Enabled Approach for in vivo Protein Kinase Analysis
Chen, F.; Liu, Q.; Hilliard, T.; Wang, T.; Liang, H.; Gao, W.; Huang, L.; Wang, D.
10.1101/2020.05.13.094573 — cell biology — Posted on 2020-07-14
2883 Liquid-liquid phase separation of full-length prion protein initiates conformational conversion in vitro
Tange, H.; Ishibashi, D.; Nakagaki, T.; Taguchi, Y.; Kamatari, Y. O.; Ozawa, H.; Nishida, N.
10.1101/2020.01.25.919340 — biochemistry — Posted on 2020-07-14
2885 A synthetic kinematic index of trunk displacement conveying the overall motor condition in Parkinson's disease
Troisi Lopez, E.; Minino, R.; Sorrentino, P.; Rucco, R.; Carotenuto, A.; Agosti, V.; Tafuri, D.; Manzo, V.; Liparoti, M.; Sorrentino, G.
10.1101/2020.07.13.199224 — neuroscience — Posted on 2020-07-14
2887 Acute stress impairs reward learning in men
Carvalheiro, J.; Conceicao, V. A.; Mesquita, A.; Seara-Cardoso, A.
10.1101/2020.07.13.200568 — neuroscience — Posted on 2020-07-14
2890 Transient receptor potential canonical 5 (TRPC5) mediates inflammatory mechanical pain
Sadler, K. E.; Moehring, F.; Shiers, S. I.; Laskowski, L. J.; Mikesell, A. R.; Plautz, Z. R.; Mecca, C. M.; Dussor, G.; Price, T. J.; McCorvy, J. D.; Stucky, C. L.
10.1101/2020.07.13.201186 — neuroscience — Posted on 2020-07-14
2894 Cortico-subcortical functional connectivity profiles of resting-state networks in marmosets and humans
Hori, Y.; Schaeffer, D. J.; Yoshida, A.; Clery, J. C.; Hayrynen, L. K.; Gati, J. S.; Menon, R. S.; Everling, S.
10.1101/2020.07.14.202382 — neuroscience — Posted on 2020-07-14
2899 An Event-Related Potential Study of Onset Primacy in Visual Change Detection
Van Pelt, J.; Lowe, B.; Robinson, J.; Donaldson, M. J.; Johnston, P.; Yamamoto, N.
10.1101/539932 — neuroscience — Posted on 2020-07-14
2900 Integrating When and What Information in the Left Parietal Lobe Allows Language Rule Generalization
Orpella, J.; Ripolles, P.; Ruzzoli, M.; Amengual, J.; Callejas, A.; Martinez-Alvarez, A.; Soto-Faraco, S.; de Diego-Balaguer, R.
10.1101/747816 — neuroscience — Posted on 2020-07-14
2907 Cortical closed-loop brain-machine interface requires biomimetic sensory feedback
Abbasi, A.; Estebanez, L.; Goueytes, D.; Lassagne, H.; Shulz, D. E.; Ego-Stengel, V.
10.1101/2019.12.12.873794 — neuroscience — Posted on 2020-07-14
2908 tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast
Tavares, J. F.; Davis, N. K.; Poim, A.; Reis, A.; Kellner, S.; Sousa, I.; Soares, A. R.; Moura, G. M. R.; Dedon, P. C.; Santos, M. A. S.
10.1101/2020.07.13.200121 — molecular biology — Posted on 2020-07-14
2909 Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease
Sullivan, R.; Randhawa, V.; Lalonde, T.; Yu, T.; Kiaii, B.; Luyt, L.; Wisenberg, G.; Dhanvantari, S.
10.1101/2020.07.13.201319 — molecular biology — Posted on 2020-07-14
2910 CB1R Regulates Soluble Leptin Receptor Levels via CHOP, Contributing to Hepatic Leptin Resistance
Drori, A.; Gammal, A.; Azar, S.; Hinden, L.; Hadar, R.; Wesley, D.; Nemirovski, A.; Szanda, G.; Salton, M.; Tirosh, B.; Tam, J.
10.1101/2020.07.14.202283 — molecular biology — Posted on 2020-07-14
2914 The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model for ATIC deficiency and ZMP accumulation
Mazzarino, R. C.; Baresova, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.04.28.067066 — cell biology — Posted on 2020-07-14
2921 Disentangling Sources of Gene Tree Discordance in Phylogenomic Datasets: Testing Ancient Hybridizations in Amaranthaceae s.l.
Morales-Briones, D. F.; Kadereit, G.; Tefarikis, D. T.; Moore, M.; Smith, S. A.; Brockington, S. F.; Timoneda, A.; Yim, W. C.; Cushman, J. C.; Yang, Y.
10.1101/794370 — evolutionary biology — Posted on 2020-07-14
2923 A decade of arbovirus emergence in the temperate southern cone of South America: dengue, Aedes aegypti; and climate dynamics in Cordoba, Argentina
Estallo, E. L.; Sippy, R.; Stewart-Ibarra, A. M.; Grech, M. G.; Benitez, E. M.; Luduena-Almeida, F. F.; Ainete, M.; Frias-Cespedes, M.; Robert, M.; Romero, M. M.; Almiron, W. R.
10.1101/2020.01.16.908814 — ecology — Posted on 2020-07-14
2925 The CRISPR-Cas9 crGART HeLa transcriptome: A novel cell model of de novo purine synthesis deficiency
Mazzarino, R. C.; Baresova, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.06.23.167924 — cell biology — Posted on 2020-07-14
2928 Diminishing effects of mechanical loading over time during rat Achilles tendon healing
Khayyeri, H.; Hammerman, M.; Turunen, M.; Blomgran, P.; Notermans, T.; Guizar-Sicairos, M.; Eliasson, P.; Isaksson, H.
10.1101/2020.07.14.202077 — bioengineering — Posted on 2020-07-14
2931 Ungulate Responses to Unmanned Aerial Vehicles Flying at Different Altitudes in Africas Arid Savanna
van Vuuren, M.; van Vuuren, R.; Silverberg, L.; Manning, J.; Pacifici, K.; Dorgeloh, W.; Campbell, J.
10.1101/2020.07.14.202093 — animal behavior and cognition — Posted on 2020-07-14
2932 Cis-regulatory differences in isoform expression associate with life history strategy variation in Atlantic salmon
Verta, J.-P.; Debes, P. V.; Piavchenko, N.; Ruokolainen, A.; Ovaskainen, O.; Moustakas-Verho, J. E.; Tillanen, S.; Parre, N.; Aykanat, T.; Erkinaro, J.; Primmer, C. R.
10.1101/777300 — evolutionary biology — Posted on 2020-07-14
2934 Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells
Kim, M.; Franke, V.; Brandt, B.; Lowenstein, E. D.; Schowel, V.; Spuler, S.; Akalin, A.; Birchmeier, C.
10.1101/2020.04.14.041665 — developmental biology — Posted on 2020-07-14
2940 Phenotypic and multi-omics characterization of Escherichia coli K-12 adapted to quaternary ammonium compounds identifies lipid A and cell envelope alterations regulated by mar-sox-rob and stress inducible pathways
Green, K. A.; Gregorchuk, B. S. J.; Reimer, S. L.; Cartwright, N. H.; Beniac, D. R.; Hiebert, S. L.; Booth, T. F.; Slipski, C. J.; Chong, P.; Westmacott, G.; Zhanel, G. G.; Bay, D. C.
10.1101/2020.07.13.201814 — microbiology — Posted on 2020-07-14
2943 Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites
Stewart, L. B.; Diez-Ingelmo, O.; Claessens, A.; Abugri, J.; Pearson, R.; Goncalves, S.; Drury, E.; Kwiatkowski, D. P.; Awandare, G. A.; Conway, D. J.
10.1101/2020.07.14.202242 — microbiology — Posted on 2020-07-14
2944 Overexpression of HLA class I predominantly on alpha cell in at risk individuals for type 1 diabetes
Benkahla, M. A.; Sabouri, S.; Kiosses, W. B.; Rajendran, S.; Quesada-Masachs, E.; von Herrath, M. G.
10.1101/2020.07.13.201079 — immunology — Posted on 2020-07-14
2945 Dendritic cells focus CTL responses toward highly conserved and topologically important HIV epitopes
Garcia-Bates, T. M.; Palma, M. L.; HSU, D. C.; Ananworanich, J.; Korber, B. T.; Gaiha, G. D.; Phanuphak, N.; Thomas, R.; Tovanabutra, S.; Walker, B. D.; Mellors, J. W.; Piazza, P. A.; Kroon, E.; Riddler, S. A.; Michael, N. L.; Rinaldo, C. R.; Mailliard, R. B.
10.1101/2020.07.13.200527 — immunology — Posted on 2020-07-14
2947 A population of CD4+ T cells with a naive phenotype stably polarized to the TH1 lineage
Lo, J. W. P.; Vila de Mucha, M.; Roberts, L. B.; Garrido-Mesa, N.; Hertweck, A.; Neves, J. F.; Stolarczyk, E.; Henderson, S.; Jackson, I.; Howard, J. K.; Jenner, R. G.; Lord, G. M.
10.1101/2020.07.14.202168 — immunology — Posted on 2020-07-14
2949 scReQTL: an approach to correlate SNVs to gene expression from individual scRNA-seq datasets
Liu, H.; Prashant, N.; Spurr, L.; Bousounis, P.; Alomran, N.; Ibeawuchi, H.; Sein, J.; Slowinski, P. M.; Tsaneva-Atanasova, K.; Horvath, A.
10.1101/2020.07.13.200956 — genomics — Posted on 2020-07-14
2950 A high-quality de novo genome assembly from a single parasitoid wasp
Ye, X.; Yang, Y.; Tian, Z.; Xu, L.; Yu, K.; Xiao, S.; Yin, C.; Xiong, S.; Fang, Q.; Chen, H.; Li, F.; Ye, G.
10.1101/2020.07.13.200725 — genomics — Posted on 2020-07-14
2955 Fluorescent in vivo editing reporter (FIVER): A novel multispectral reporter of in vivo genome editing
Tennant, P. A.; Foster, R. G.; Dodd, D. O.; Sou, I. F.; McPhie, F.; Younger, N.; Murphy, L. C.; Pearson, M.; Vernay, B.; Keighren, M. A.; Budd, P.; Hart, S. L.; Megaw, R.; Boulter, L.; Mill, P.
10.1101/2020.07.14.200170 — genetics — Posted on 2020-07-14
2957 SMPD3-mediated extracellular vesicle biogenesis inhibits oligodendroglioma growth
Balakrishnan, A.; Adnani, L.; Chinchalongporn, V.; Vasan, L.; Prokopchuk, O.; Chen, M.; El-Sehemy, A.; Olender, T.; Touahri, Y.; Ahmad, S. T.; Islam, R.; Sujanthan, S.; Zinyk, D.; Comanita, L. C.; Kan, B.; Fleming, T.; Leong, H. S.; Morshead, C. M.; Brand, M.; Wallace, V. A.; Chan, J. A.; Schuurmans, C.
10.1101/2020.07.14.202200 — cancer biology — Posted on 2020-07-14
2964 Active synthesis of collagen (I) homotrimer and matrisomal proteins in Dupuytren's fibrosis
Williamson, K.; Lee, K. J.; Beamish, E. L.; Simpson, D.; Carter, A.; Gumbs, J. A.; Cheung, G.; Brown, D.; Pettitt, R.; Comerford, E. J.; Clegg, P. D.; Canty-Laird, E. G.
10.1101/2020.07.13.195107 — cell biology — Posted on 2020-07-14
2966 A cell non-autonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism
Hesles, E. E.; Smith, D. L.; Maqani, N. S.; Wierman, M. B.; Sutcliffe, M. D.; Fine, R. D.; Kalita, A.; Santos, S. M.; Muehlbauer, M. J.; Bain, J. R.; Janes, K. A.; Hartman, J. L.; Hirschey, M. D.; Smith, J. S.
10.1101/2020.07.13.200493 — cell biology — Posted on 2020-07-14
2971 Spatial Deconvolution of HER2-positive Breast Tumors Reveals Novel Intercellular Relationships
Andersson, A. E. V.; Larsson, L.; Stenbeck, L.; Salmen, F.; Ehinger, A.; Wu, S. Z.; Al-Eryani, G.; Roden, D. L.; Swarbrick, A.; Borg, A.; Frisen, J.; Engblom, C.; Lundeberg, J.
10.1101/2020.07.14.200600 — cancer biology — Posted on 2020-07-14
2973 Curation of over 10,000 transcriptomic studies to enable data reuse
Lim, N.; Tesar, S.; Belmadani, M.; Poirier-Morency, G.; Mancarci, B. O.; Sicherman, J.; Jacobson, M.; Leong, J.; Tan, P.; Pavlidis, P.
10.1101/2020.07.13.201442 — bioinformatics — Posted on 2020-07-14
2980 Evaluation of consensus strategies for haplotype phasing
Al Bkhetan, Z.; Chana, G.; Ramamohanarao, K.; Verspoor, K.; Goudey, B.
10.1101/2020.07.13.175786 — bioinformatics — Posted on 2020-07-14
2983 Multi-Task Learning based 3-Dimensional Striatal Segmentation of MRI - a Multi-modal Objective Assessment
Serrano-Sosa, M.; Van Snellenberg, J. X.; Meng, J.; Spuhler, K.; Weinstein, J. J.; Abi-Dargham, A.; Slifstein, M.; Huang, C.
10.1101/2020.07.13.200576 — bioengineering — Posted on 2020-07-14
2984 Updates on enzymatic and structural properties of human glutamine: fructose-6-phosphate amidotransferase 2 (hGFAT2)
Oliveira, I. A.; Allonso, D.; Fernandes, T. V. A.; Lucena, D. M. S.; Ventura, G. T.; Dias, W. B.; Mohana-Borges, R.; Pascutti, P. G.; Todeschini, A. R.
10.1101/2020.07.13.201285 — biochemistry — Posted on 2020-07-14
2985 Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2
Schmidt, S. H.; Weng, J.-H.; Aoto, P. C.; Boassa, D.; Mathea, S.; Silletti, S.; Hu, J.; Wallbott, M.; Komives, E. A.; Knapp, S.; Herberg, F. W.; Taylor, S. S.
10.1101/2020.07.13.198069 — biochemistry — Posted on 2020-07-14
2988 Insecticide resistance status of malaria vectors Anopheles gambiae s.l of southwest Burkina Faso and residual efficacy of indoor residual spraying with microencapsulated pirimiphos-methyl insecticide
Soma, D. D.; Zogo, B. M.; Hien, F. D.; Hien, A. S.; Kabore, D. P. A.; Kientega, M.; Ouedraogo, A. G.; Pennetier, C.; Koffi, A. A.; Moiroux, N.; Dabire, R. K.
10.1101/2020.07.13.200865 — systems biology — Posted on 2020-07-14
2989 A CRISPR-based genome-wide screen for adipogenesis reveals new insights into mitotic expansion and lipogenesis.
Hilgendorf, K. I.; Johnson, C. T.; Han, K.; Rabiee, A.; Demeter, J.; Cheng, R.; Zhu, Y.; Jiang, Z.; Svensson, K. J.; Bassik, M. C.; Jackson, P. K.
10.1101/2020.07.13.201038 — molecular biology — Posted on 2020-07-14
2993 Structural basis of αE-catenin-F-actin catch bond behavior
Xu, X.-P.; Pokutta, S.; Torres, M.; Swift, M. F.; Hanein, D.; Volkmann, N.; Weis, W. I.
10.1101/2020.07.13.201236 — biophysics — Posted on 2020-07-14
2994 Activating a collaborative innate-adaptive immune response to control breast and ovarian cancer metastasis
Sun, L.; Kees, T.; Almeida, A. S.; Liu, B.; He, X.-Y.; Ng, D.; Spector, D.; McNeish, I. M.; Gimotty, P.; Adams, S.; EGEBLAD, M.
10.1101/2020.07.13.200477 — cancer biology — Posted on 2020-07-14
2995 Vascular Endothelial Growth Factor as an Immediate-Early Activator of UV-induced Skin Injury
Hartono, S.; Bedell, V. M.; Alam, S. K.; O'Gorman, M.; Serres, M.; Hall, S. R.; Pal, K.; Kudgus, R. A.; Mukherjee, P.; Seelig, D.; Meves, A.; Mukhopadhyay, D.; Ekker, S. C.; Hoeppner, L. H.
10.1101/2020.07.13.198549 — molecular biology — Posted on 2020-07-14
2998 Dot1L interacts with Zc3h10 to activate UCP1 and other thermogenic genes
Yi, D.; Nguyen, H. P.; Dinh, J.; Viscarra, J. A.; Xie, Y.; Dempersmier, J. M.; Wang, Y.; Sul, H. S.
10.1101/2020.06.22.154963 — developmental biology — Posted on 2020-07-14
2999 Endochondral bone in an Early Devonian 'placoderm' from Mongolia
Brazeau, M.; Giles, S.; Dearden, R.; Jerve, A.; Ariunchimeg, Y.; Zorig, E.; Guillerme, T.; Castiello, M.
10.1101/2020.06.09.132027 — paleontology — Posted on 2020-07-13
3007 Interpretable Machine Learning for Perturbation Biology
Yuan, B.; Shen, C.; Luna, A.; Korkut, A.; Marks, D.; Ingraham, J.; Sander, C.
10.1101/746842 — systems biology — Posted on 2020-07-13
3009 Fast and sensitive diffuse correlation spectroscopy with highly parallelized single photon detection
Liu, W.; Qian, R.; Xu, S.; Konda, P. C.; Harfouche, M.; Borycki, D.; Jonsson, J.; Berrocal, E.; Cooke, C.; Wang, H.; Dai, Q.; Horstmeyer, R. W.
10.1101/2020.07.08.193433 — neuroscience — Posted on 2020-07-13
3010 Microbiome Dynamics of Bovine Mastitis Progression and Genomic Determinants
Hoque, M. N.; Istiaq, A.; Rahman, M. S.; Islam, M. R.; Anwar, A.; Siddiki, A. Z.; Sultana, M.; Crandall, K. A.; Hossain, M. A.
10.1101/2020.07.13.200808 — microbiology — Posted on 2020-07-13
3011 Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing
Leibowitz, M. L.; Papathanasiou, S.; Doerfler, P. A.; Blaine, L. J.; Yao, Y.; Zhang, C.-Z.; Weiss, M. J.; Pellman, D.
10.1101/2020.07.13.200998 — genetics — Posted on 2020-07-13
3014 Pyk2 Overexpression in Postsynaptic Neurons Blocks Aβ1-42-induced Synaptotoxicity in a Microfluidic Co-Culture Model
Kilinc, D.; Vreulx, A.-C.; Mendes, T.; Flaig, A.; Marques-Coelho, D.; Verschoore, M.; Demiautte, F.; Amouyel, P.; Neuro-CEB Brain Bank, ; Eysert, F.; Dourlen, P.; Chapuis, J.; Costa, M. R.; Malmanche, N.; Checler, F.; Lambert, J.-C.
10.1101/2019.12.20.884205 — neuroscience — Posted on 2020-07-13
3015 DeepACSON: Automated Segmentation of White Matter in 3D Electron Microscopy
Abdollahzadeh, A.; Belevich, I.; Jokitalo, E.; Sierra, A.; Tohka, J.
10.1101/828541 — neuroscience — Posted on 2020-07-13
3017 Prophage-encoded phage defence proteins with cognate self-immunity
Owen, S. V.; Wenner, N.; Dulberger, C. L.; Rodwell, E. V.; Bowers-Barnard, A.; Quinones-Olvera, N.; Rigden, D. J.; Rubin, E. J.; Garner, E. C.; Baym, M.; Hinton, J. C. D.
10.1101/2020.07.13.199331 — microbiology — Posted on 2020-07-13
3018 Biodiversity Soup II: A bulk-sample metabarcoding pipeline emphasizing error reduction
Yang, C.; Bohmann, K.; Wang, X.; Cai, W.; Wales, N.; Ding, Z.; Gopalakrishnan, S.; Yu, D. W.
10.1101/2020.07.07.187666 — ecology — Posted on 2020-07-13
3019 BERTology Meets Biology: Interpreting Attention in Protein Language Models
Vig, J.; Madani, A.; Varshney, L. R.; Xiong, C.; Socher, R.; Rajani, N. F.
10.1101/2020.06.26.174417 — bioinformatics — Posted on 2020-07-13
3023 Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs, Plakobranchus ocellatus
Maeda, T.; Takahashi, S.; Yoshida, T.; Shimamura, S.; Takaki, Y.; Nagai, Y.; Toyoda, A.; Suzuki, Y.; Arimoto, A.; Ishii, H.; Satoh, N.; Nishiyama, T.; Hasebe, M.; Maruyama, T.; Minagawa, J.; Obokata, J.; Shigenobu, S.
10.1101/2020.06.16.155838 — evolutionary biology — Posted on 2020-07-13
3024 MORPHO-MOLECULAR MECHANISMS STUDY OF PHOTODYNAMIC THERAPY AND CURCUMIN LARVICIDE ACTION ON WILD MOSQUITOES LARVAE OF GENUS Aedes
Araujo, B.; Silva, E.; Rosa, L.; Inada, N.; Iermak, I.; Romano, R.; Mezzacappo, N.; Melo, F.; Silva, F.; Silva, R.; Galantini, M.; Silveira, E.; Garbuio, M.; Rocha, M.
10.1101/2020.07.13.200295 — bioengineering — Posted on 2020-07-13
3026 Worldwide Geographical and Temporal Analysis of SARS-CoV-2 Haplotypes shows Differential Distribution Patterns
Justo Arevalo, S.; Zapata Sifuentes, D.; Huallpa Robles, C.; Landa Bianchi, G.; Castillo Chavez, A.; Garavito-Salini Casas, R.; Uceda-Campos, G.; Pineda Chavarria, R.
10.1101/2020.07.12.199414 — genomics — Posted on 2020-07-13
3028 An interpretable classification method for predicting drug resistance in M. tuberculosis
Zabeti, H.; Dexter, N.; Safari, A. H.; Sedaghat, N.; Libbrecht, M.; Chindelevitch, L.
10.1101/2020.05.31.115741 — bioinformatics — Posted on 2020-07-13
3029 Upper extremity exomuscle for shoulder abduction support
Simpson, C.; Huerta, B.; Sketch, S.; Lansberg, M.; Hawkes, E.; Okamura, A.
10.1101/2020.04.25.061846 — bioengineering — Posted on 2020-07-13
3031 Development of a humanized mouse model to analyze antibodies specific for human leukocyte antigen (HLA)
Yanagawa, S.; Tahara, H.; Shirouzu, T.; Kawai, S.; Tanaka, Y.; Ide, K.; Akimoto, S.; Ohdan, H.
10.1101/2020.07.13.200394 — immunology — Posted on 2020-07-13
3032 Mutational profiling of micro-dissected pre-malignant lesions from archived specimens
Nachmanson, D.; Steward, J.; Yao, H.; Officer, A.; Jeong, E.; O'Keefe, T. J.; Hasteh, F.; Jepsen, K.; Hirst, G. L.; Esserman, L. J.; Borowsky, A. D.; Harismendy, O.
10.1101/2020.04.05.026708 — genomics — Posted on 2020-07-13
3035 Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk
Pined, S.; Nikolova-Krstevski, V.; Leimena, C.; Atkinson, A. J.; Altekoester, A.-K.; Cox, C. D.; Jacoby, A.; Huttner, I. G.; Ju, Y.-K.; Soka, M.; Ohanian, M.; Trived, G.; Kalvakuri, S.; Johnson, R.; Molenaar, P.; Kuchar, D.; Allen, D. G.; Van Helden, D.; Harvey, R. P.; Hill, A. P.; Bodmer, R.; Vogler, G.; Dobrzyn, H.; Ocorr, K.; Fatkin, D.
10.1101/2020.06.28.176495 — genetics — Posted on 2020-07-13
3036 A quantised cyclin-based cell cycle model
coulter, J.; Emerson, C.; Bennie, L.; Green, D.; Currell, F.
10.1101/2020.07.13.200303 — cell biology — Posted on 2020-07-13
3053 What would it take to describe the global diversity of parasites?
Carlson, C. J.; Dallas, T. A.; Alexander, L. W.; Phelan, A.; Phillips, A. J.
10.1101/815902 — ecology — Posted on 2020-07-13
3054 Lack of phenotypic variation despite population structure in larval utilization of pea aphids by populations of the lady beetle Hippodamia convergens
Grenier, C.; Summerhays, B.; Cartmill, R.; Martinez, T.; Saisho, R.; Rothenberg, A.; Scott, J.; Obrycki, J.; Tovar, A.; Rynerson, A.; Sethuraman, A.
10.1101/740506 — ecology — Posted on 2020-07-13
3055 Identification of Six novel missense single nucleotide polymorphisms in MAOA gene predisposing to aggressive behavior. Bioinformatics study.
Abdelmoneim, A. H.; Mustafa, M. I.; Murshed, N. S.; Omer, N. S.; Mohammed, A. I.; Abdulmajed, R. A.; Dawoud, E. d.; Makhawi, A. M.
10.1101/2019.12.18.880963 — bioinformatics — Posted on 2020-07-13
3057 Cell-scale biophysical determinants of cell competition in epithelia
Gradeci, D.; Bove, A.; Vallardi, G.; Lowe, A.; Banerjee, S.; Charras, G.
10.1101/729731 — biophysics — Posted on 2020-07-13
3058 Animal Model Prescreening: Pre-exposure to SARS-CoV-2 impacts responses in the NHP model
Ricks, K. M.; Herbert, A. S.; Koehler, J. W.; Kuehnert, P. A.; Clements, T. L.; Shoemaker, C. J.; Kuehne, A. I.; O'Brien, C. M.; Coyne, S. R.; Delp, K. L.; Akers, K. S.; Dye, J. M.; Hooper, J. W.; Smith, J. M.; Kugelman, J. R.; Beitzel, B. F.; Gibson, K. M.; Johnston, S. C.; Minogue, T. D.
10.1101/2020.07.06.189803 — immunology — Posted on 2020-07-13
3059 If the link missed: Could inflammatory skin disorders with barrier dysfunction increase the risk of COVID-19?
Xu, Q.; Chen, L.; Zhang, L.; Hu, M.; Wang, X.; Yang, Q.; Le, Y.; Xue, F.; Li, X.; Zheng, J.
10.1101/2020.06.30.181297 — pathology — Posted on 2020-07-13
3061 Ex vivo observation of granulocyte activity during thrombus formation
Morozova, D. S.; Martyanov, A.; Obydennyi, S.; Korobkin, J.-J.; Sokolov, A. V.; Shamova, E. V.; Gorudko, I. V.; Shcherbina, A.; Panteleev, M. A.; Sveshnikova, A. N.
10.1101/2020.07.13.199174 — immunology — Posted on 2020-07-13
3062 Early Medieval Genetic Data from Ural Region Evaluated in the Light of Archaeological Evidence of Ancient Hungarians
Csaky, V.; Gerber, D.; Szeifert, B.; Egyed, B.; Stegmar, B.; Botalov, S. G.; Grudochko, I. V.; Matvejeva, N. P.; Zelenkov, A. S.; Slepcova, A. V.; Goldina, R. D.; Danich, A. V.; Mende, B. G.; Turk, A.; Szecsenyi-Nagy, A.
10.1101/2020.07.13.200154 — genetics — Posted on 2020-07-13
3067 Extracellular matrix supports excitation-inhibition balance in neuronal networks by stabilizing inhibitory synapses
Dzyubenko, E.; Fleischer, M.; Manrique-Castano, D.; Borbor, M.; Kleinschnitz, C.; Faissner, A.; Hermann, D. M.
10.1101/2020.07.13.200113 — neuroscience — Posted on 2020-07-13
3069 The RNA helicase DHX30 coordinates cytoplasmic translation and mitochondrial function contributing to cancer cell survival
Bosco, B.; Rossi, A.; Rizzotto, D.; Giorgetta, S.; Perzolli, A.; Bonollo, F.; Gaucherot, A.; Catez, F.; Diaz, J.-J.; Dassi, E.; Inga, A.
10.1101/2020.07.13.196709 — molecular biology — Posted on 2020-07-13
3072 Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19
Sales-Medina, D. F.; Ferreira, L. R. P.; Romera, L. M. D.; Goncalves, K. R.; Guido, R. V. C.; Courtemanche, G.; Buckeridge, M. S.; Durigon, E. L.; Moraes, C. B.; Freitas Junior, L.
10.1101/2020.07.09.196337 — microbiology — Posted on 2020-07-13
3075 How robust are cross-population signatures of polygenic adaptation in humans?
Refoyo-Martinez, A.; Liu, S.; Jorgensen, A. M.; Jin, X.; Albrechtsen, A.; Martin, A. R.; Racimo, F.
10.1101/2020.07.13.200030 — genetics — Posted on 2020-07-13
3077 Pan-genome analyses of peach and its wild relatives provide insights into the genetics of disease resistance and species adaptation
Cao, K.; Peng, Z.; Zhen, X.; Li, Y.; Liu, K.; Arus, P.; Zhu, G.; Deng, S.; Fang, W.; Chen, C.; Wang, X.; Wu, J.; Fei, Z.; Wang, L.
10.1101/2020.07.13.200204 — plant biology — Posted on 2020-07-13
3078 Genomic variations in SARS-CoV-2 genomes from Gujarat: Underlying role of variants in disease epidemiology
Joshi, M.; Puvar, A. C.; Kumar, D.; Ansari, A.; Pandya, M.; Raval, J.; Patel, Z.; Trivedi, P.; Gandhi, M.; Pandya, L.; Patel, K.; Savaliya, N.; Bagatharia, S.; Kumar, S.; Joshi, C.
10.1101/2020.07.10.197095 — genomics — Posted on 2020-07-13
3079 Comparative analysis of chloroplast genomes indicated different origin for Indian Tea (Camellia assamica) cv TV-1 as compared to Chinese tea
Rawal, H. C.; Mazumder, A.; Borchetia, S.; Bera, B.; Soundararajan, S.; Ilango, R. V. J.; Barooah, A. K.; Singh, N. K.; Mondal, T. K.
10.1101/2020.07.13.199133 — genomics — Posted on 2020-07-13
3084 Intraneuronal chloride accumulation via NKCC1 is not essential for hippocampal network development in vivo
Graf, J.; Zhang, C.; Marguet, S. L.; Herrmann, T.; Flossmann, T.; Hinsch, R.; Rahmati, V.; Guenther, M.; Frahm, C.; Urbach, A.; Neves, R. M.; Witte, O. W.; Kiebel, S. J.; Isbrandt, D.; Hübner, C. A.; Holthoff, K.; Kirmse, K.
10.1101/2020.07.13.200014 — neuroscience — Posted on 2020-07-13
3086 Modulating the transcriptional landscape of SARS-CoV-2 as an effective method for developing antiviral compounds
Hoagland, D. A.; Clarke, D. J. B.; Moeller, R.; Han, Y.; Yang, L.; Wojciechowicz, M. L.; Lachmann, A.; Oguntuyo, K. Y.; Stevens, C.; Lee, B.; Chen, S.; Ma'ayan, A.; tenOever, B. R.
10.1101/2020.07.12.199687 — microbiology — Posted on 2020-07-13
3087 Endosomal trafficking is required for glycosylation and normal maturation of the Alzheimer's-associated protein sorLA
Christensen, S. K.; Narimatsu, Y.; Simoes, S.; Goth, C. K.; Vaegter, C. B.; Small, S. A.; Clausen, H.; Andersen, O. M.
10.1101/2020.07.12.199885 — cell biology — Posted on 2020-07-13
3093 PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.
Theise, N. D.; Arment, A. R.; Chakravarty, D.; Gregg, J. M. H.; Jacobson, I. M.; Jung, K. H.; Nair, S. S.; Tiwari, A.; Thurston, A. W.; Van Drie, J.; Westover, J. B.
10.1101/2020.07.12.199505 — microbiology — Posted on 2020-07-13
3094 Tobacco, but not nicotine and flavor-less electronic cigarettes, induces ACE2 and immune dysregulation
Lee, A. C.; Chakladar, J.; Li, W. T.; Chen, C.; Chang, E. Y.; Wang-Rodriguez, J.; Ongkeko, W. M.
10.1101/2020.07.13.198630 — immunology — Posted on 2020-07-13
3095 Divergence and Remarkable Diversity of the Y Chromosome in Guppies
Almeida, P.; Sandkam, B. A.; Morris, J.; Darolti, I.; Breden, F.; Mank, J. E.
10.1101/2020.07.13.200196 — evolutionary biology — Posted on 2020-07-13
3096 Long-term live imaging of epithelial organoids and corresponding multiscale analysis reveal high heterogeneity and identifies core regulatory principles
Hof, L.; Moreth, T.; Koch, M.; Liebisch, T.; Kurtz, M.; Tarnick, J.; Lissek, S. M.; Verstegen, M. M.; van der Laan, L. J.; Huch, M.; Matthaeus, F.; Stelzer, E. H.; Pampaloni, F.
10.1101/2020.07.12.199463 — cell biology — Posted on 2020-07-13
3098 Efficient Sequencing, Assembly, and Annotation of Human KIR Haplotypes
Roe, D.; Williams, J.; Ivery, K.; Brouckaert, J.; Downey, N.; Locklear, C.; Kuang, R.; Maiers, M.
10.1101/2020.07.12.199570 — bioinformatics — Posted on 2020-07-13
3101 Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Hoepel, W.; Chen, H.-J.; Allahverdiyeva, S.; Manz, X.; Aman, J.; Bonta, P.; Brouwer, P.; de Taeye, S.; Caniels, T.; van der Straten, K.; Golebski, K.; Griffith, G.; Jonkers, R.; Larsen, M.; Linty, F.; Neele, A.; Nouta, J.; van Baarle, F.; van Drunen, C.; Vlaar, A.; de Bree, G.; Sanders, R.; Willemsen, L.; Wuhrer, M.; Bogaard, H. J.; van Gils, M.; Vidarsson, G.; de Winther, M. P. J.; den Dunnen, J.
10.1101/2020.07.13.190140 — immunology — Posted on 2020-07-13
3105 Cold sensitivity of the SARS-CoV-2 spike ectodomain
Edwards, R. J.; Mansouri, K.; Stalls, V.; Manne, K.; Watts, B.; Parks, R.; Gobeil, S. M. C.; Janowska, K.; Li, D.; Lu, X.; Deyton, M.; Sprenz, J.; Williams, W.; Saunders, K.; Sempowski, G. D.; Henderson, R.; Alam, M.; Haynes, B. F.; Acharya, P.
10.1101/2020.07.12.199588 — biochemistry — Posted on 2020-07-13
3107 Potential silencing of gene expression by PIWI-interacting RNAs (piRNAs) in somatic tissues in mollusk
Huang, S.; Ichikawa, Y.; Yoshitake, K.; Igarashi, Y.; Mariom, ; Kinoshita, S.; Asaduzzaman, M.; Omori, F.; Maeyama, K.; Nagai, K.; Watabe, S.; Asakawa, S.
10.1101/2020.07.12.199877 — molecular biology — Posted on 2020-07-13
3110 Cigarette Smoke and Nicotine-Containing E-cigarette Vapor Downregulate Lung WWOX Expression Which is Associated with Increased Severity of Murine ARDS
Zeng, Z.; Chen, W.; Moshensky, A.; Khan, R.; Alexander, L. C.; Ware, L. B.; Aldaz, C. M.; Jacobson, J. R.; Dudek, S. M.; Natarajan, V.; Machado, R. F.; Singla, S.
10.1101/2020.07.13.200832 — molecular biology — Posted on 2020-07-13
3113 Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium
Ravindra, N. G.; Alfajaro, M. M.; Gasque, V.; Wei, J.; Filler, R. B.; Huston, N. C.; Wan, H.; Szigeti-Buck, K.; Wang, B.; Montgomery, R. R.; Eisenbarth, S. C.; Williams, A.; Pyle, A. M.; Iwasaki, A.; Horvath, T. L.; Foxman, E. F.; Pierce, R. W.; van Dijk, D.; Wilen, C.
10.1101/2020.05.06.081695 — bioinformatics — Posted on 2020-07-13
3114 Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.
Lokugamage, K. G.; Hage, A.; Devries, M.; Vallero-Jimenez, A. M.; Schindewolf, C.; Dittmann, M.; Rajsbaum, R.; Menachery, V. D.
10.1101/2020.03.07.982264 — microbiology — Posted on 2020-07-13
3115 Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex
Chen, J.; Malone, B.; Llewellyn, E.; Grasso, M.; Shelton, P. M. M.; Olinares, P. D. B.; Maruthi, K.; Eng, E. T.; Vatandaslar, H.; Chait, B.; Kapoor, T.; Darst, S. A.; Campbell, E. A.
10.1101/2020.07.08.194084 — biophysics — Posted on 2020-07-13
3118 DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopment disorders
Christian, D. L.; Wu, D. Y.; Martin, J. R.; Moore, J. R.; Liu, Y. R.; Clemens, A. W.; Nettles, S. A.; Kirkland, N. M.; Hill, C. A.; Wozniak, D. F.; Dougherty, J. D.; Gabel, H. W.
10.1101/2020.07.10.195859 — neuroscience — Posted on 2020-07-13
3119 Collateral Sensitivity Associated with Antibiotic Resistance Plasmids
Herencias, C.; Rodriguez-Beltran, J.; Leon-Sampedro, R.; Palkovicova, J.; Canton, R.; San Millan, A.
10.1101/2020.07.10.198259 — microbiology — Posted on 2020-07-13
3120 Plant diversity and community age shape soil microbial communities
Schmid, M. W.; van Moorsel, S. J.; Hahl, T.; De Luca, E.; Wagg, C.; Niklaus, P. A.; Schmid, B.
10.1101/2020.07.08.193409 — ecology — Posted on 2020-07-13
3121 Constrained non-coding sequence provides insights into regulatory elements and loss of gene expression in maize
Song, B.; Wang, H.; Wu, Y.; Rees, E.; Gates, D. J.; Burch, M.; Bradbury, P.; Ross-Ibarra, J.; Kellogg, E.; Hufford, M.; Romay, M. C.; Buckler, E. S.
10.1101/2020.07.11.192575 — evolutionary biology — Posted on 2020-07-13
3125 Evaluating High Spatial Resolution Diffusion Kurtosis Imaging at 3T: Reproducibility and Quality of Fit
Loxlan W Kasa; Roy AM Haast; Tristan K Kuehn; Farah N Mushtaha; Corey A Baron; Terry M Peters; Ali R Khan
10.1101/2020.07.10.197921 — neuroscience — Posted on 2020-07-12
3127 Controllability over stressor decreases responses in key threat-related brain areas
Chirag Limbachia; Kelly Morrow; Anastasiia Khibovska; Christian T Meyer; Srikanth Padmala; Luiz Pessoa
10.1101/2020.07.11.198762 — neuroscience — Posted on 2020-07-12
3129 Anxiety makes time pass quicker: neural correlates
Ioannis Sarigiannidis; Karel Kieslich; Christian Grillon; Monique Ernst; Jonathan Roiser; Oliver J Robinson
10.1101/2020.07.11.198390 — neuroscience — Posted on 2020-07-12
3132 TET1-DNA Hydroxymethylation Mediated Oligodendrocyte Homeostasis is Required for CNS Myelination and Remyelination
Ming Zhang; Jian Wang; Kaixiang Zhang; Guozhen Lu; Keke Ren; Wenting Wang; Honghui Mao; Junlin Xing; Xingchun Gao; Weilin Jin; Kalen Berry; Hehuang Xie; Shengxi Wu; Qing Richard Lu; Xianghui Zhao
10.1101/821496 — neuroscience — Posted on 2020-07-12
3134 Distributed control of motor circuits for backward walking in Drosophila
Kai Feng; Rajyashree Sen; Ryo Minegishi; Michael Duebbert; Till Bockemuehl; Ansgar Bueschges; Barry Dickson
10.1101/2020.07.11.198663 — neuroscience — Posted on 2020-07-12
3135 Independence of Cued and Contextual Components of Fear Conditioning is Gated by the Lateral Habenula
Tomas E Sachella; Marina R Ihidoype; Christophe Proulx; Jorge H Medina; Pablo Mendez; Joaquin Piriz
10.1101/2020.07.12.197319 — neuroscience — Posted on 2020-07-12
3141 Individual differences in frontal midline theta activity during visuomotor adaptation are related to execution noise
Zeb D. Jonker; Rick van der Vliet; Guido Maquelin; Joris van der Cruijsen; Gerard M. Ribbers; Ruud W. Selles; Opher Donchin; Maarten A. Frens
10.1101/2020.07.12.188581 — neuroscience — Posted on 2020-07-12
3142 Dynamics of history-dependent perceptual judgment
Iacopo Hachen; Sebastian Reinartz; Romain Brasselet; Alisea Stroligo; Mathew Ernest Diamond
10.1101/2020.07.12.199489 — neuroscience — Posted on 2020-07-12
3143 Wide phenotypic spectrum of human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations
Rebecca SF Mok; Wen-Bo Zhang; Taimoor I Sheikh; Isabella R Fernandes; Leah C DeJong; Matthew R Hildebrandt; Marat Mufteev; Deivid C Rodrigues; Wei Wei; Alina Piekna; Jiajie Liu; Alysson R Muotri; John B Vincent; Michael W Salter; James Ellis
10.1101/2020.07.12.189621 — neuroscience — Posted on 2020-07-12
3146 Analysis of genomic DNA methylation and gene transcription modulation induced by DNMT3A deficiency in HEK293 cells
Mengxiao Zhang; Jiaxian Wang; Qiuxiang Tian; Lei Feng; Hui Yang Yang; Nan Zhu; Xingchen Pan; Jianwei Zhu; Peng Chen; Huili Lu
10.1101/2020.07.11.198895 — molecular biology — Posted on 2020-07-12
3147 Sub-3 Å resolution structure of 110 kDa nitrite reductase determined by 200 kV cryogenic electron microscopy
Naruhiko Adachi; Takahide Yamaguchi; Toshio Moriya; Masato Kawasaki; Kotaro Koiwai; Akira Shinoda; Yusuke Yamada; Fumiaki Yumoto; Takamitsu Kohzuma; Toshiya Senda
10.1101/2020.07.12.199695 — molecular biology — Posted on 2020-07-12
3149 Fungal mycelia and bacterial thiamine establish a mutualistic growth mechanism
Gayan Abeysinghe; Momoka Kuchira; Gamon Kudo; Shunsuke Masuo; Akihiro Ninomiya; Kohei Takahashi; Andrew S. Utada; Daisuke Hagiwara; Nobuhiko Nomura; Naoki Takaya; Nozomu Obana; Norio Takeshita
10.1101/2020.07.12.199612 — microbiology — Posted on 2020-07-12
3151 Pairwise Interactions in Adjuvant Combinations Dictate Immune Responses and Inform Cancer Immunotherapy Design
Surya Pandey; Adam Gruenbaum; Tamara Kashanova; Philipp Mertins; Philippe Cluzel; Nicolas Chevrier
10.1101/2020.07.11.198879 — immunology — Posted on 2020-07-12
3152 Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells
Siobhan Crittenden; Marie Goepp; Jolinda Pollock; Calum T Robb; Danielle J Smyth; You Zhou; Robert Andrews; Victoria Tyrrell; Alexander Adima; Richard A OConnor; Luke Davies; Xue-Feng Li; Hatti X Yao; Gwo-Tzer Ho; Xiaozhong Zheng; Amil Mair; Sonja Vermeren; Binzhi Qian; Damian James Mole; Jurgen Schwarze; Richard M Breyer; Mark J Arends; Valerie O'Donnell; John P Iredale; Stephen M Anderton; Shuh Narumiya; Rick M Maizels; Adriano G Rossi; Sarah E Howie; Chengcan Yao
10.1101/2020.07.12.199513 — immunology — Posted on 2020-07-12
3153 The spatial proteome of the human intervertebral disc reveals architectural changes in health, ageing and degeneration
Vivian Tam; Peikai Chen; Anita Yee; Nestor Solis; Theo Klein; Mateusz Kudelko; Rakesh Sharma; Wilson CW Chan; Christopher M Overall; Lisbet Haglund; Pak C Sham; Kathryn SE Cheah; Danny Chan
10.1101/2020.07.11.192948 — systems biology — Posted on 2020-07-12
3156 A cost-effective maize ear phenotyping platform enables rapid categorization and quantification of kernels
Cedar Warman; Christopher M Sullivan; Justin Preece; Michaela E Buchanan; Zuzana Vejlupkova; Pankaj Jaiswal; John E Fowler
10.1101/2020.07.12.199000 — plant biology — Posted on 2020-07-12
3157 Friendly regulates membrane depolarization induced mitophagy in Arabidopsis
Juncai Ma; Zizhen Liang; Jierui Zhao; Pengfei Wang; Wenlong Ma; Juan A. Fernandez Andrade; Yonglun Zeng; Nenad Grujic; Liwen Jiang; Yasin Dagdas; Byung-Ho Kang
10.1101/2020.07.12.198424 — plant biology — Posted on 2020-07-12
3159 UGT76B1, a promiscuous hub of small molecule-based immune signaling, glucosylates N-hydroxypipecolic acid and controls basal pathogen defense
Sibylle Bauer; Dereje W Mekonnen; Michael Hartmann; Robert Janowski; Birgit Lange; Birgit Geist; Juergen Zeier; Anton R Schaeffner
10.1101/2020.07.12.199356 — plant biology — Posted on 2020-07-12
3161 Acute changes in systemic glycaemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis
Wineke Bakker; Casper Gravesen Salinas; Monica Imbernon; Daniela Herrera Moro Chao; Rim Hassouna; Chloe Morel; Claire Martin; Giuseppe Gangarossa; Raphael GP Denis; Julien Castel; Andreas Peter; Martin Heni; Walter Matzler; Heidi Solvang Nielsen; Manon Duquenne; Anna Secher; Jacob Hecksher-Sorensen; Thomas Askov Pedersen; Vincent Prevot; Serge H Luquet
10.1101/2020.07.11.198341 — physiology — Posted on 2020-07-12
3164 Loss of Circadian Protection in Adults Exposed to Hyperoxia as Neonates
Yasmine A Issah; Amruta Naik; Soon Yew Tang; Kaitlyn Forrest; Thomas G Brooke; Nicholas Lahens; Katherine N Theken; Amita Sehgal; Scott G Worthen; Garret A FitzGerald; Shaon Sengupta
10.1101/2020.07.10.197277 — pathology — Posted on 2020-07-12
3165 STING Promotes Breast Cancer Cell Survival by an Inflammatory-Independent Nuclear Pathway Enhancing the DNA Damage Response
Laura Cheradame; Ida C Guerrera; Julie Gaston; Alain Schmitt; Vincent Jung; Marion Pouillard; Nina Radosevic-Robin; Mauro Modesti; Jean-Gabriel Judde; Stefano Cairo; Vincent Goffin
10.1101/2020.07.11.196790 — cancer biology — Posted on 2020-07-12
3168 Multi-Drug-Resistance in Drug-Sensitive and Drug-Resistant Ovarian Cancer Cells Responds Differently to Cell Culture Dimensionality
Vasilij Koshkin; Mariana Bleker de Oliveira; Chun Peng; Laurie E Ailles; Geoffrey Liu; Allan Covens; Sergey N Krylov
10.1101/2020.07.12.199125 — cancer biology — Posted on 2020-07-12
3169 A diffusion-like process enables expansion of advantaged gene mutations in human colonic epithelium
Cora Olpe; Doran Khamis; Maria Chukanova; Richard Kemp; Kate Marks; Cerys Tatton; Cecilia Lindskog; Nefeli Skoufou-Papoutsaki; Anna M Nicholson; Roxanne Brunton-Sim; Shalini Malhotra; Rogier ten Hoopen; Rachel Stanley; Edward Morrissey; Douglas J Winton
10.1101/2020.07.10.193748 — cancer biology — Posted on 2020-07-12
3174 Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to SLC7A11 inhibition
George Sharbeen; Joshua A McCarroll; Anouschka Akerman; Chantal Kopecky; Janet Youkhana; Jeff Holst; Cyrille Boyer; Mert Erkan; David Goldstein; Paul Timpson; Thomas R Cox; Brooke A Pereira; Jessica L Chitty; Sigrid Fey; Arafath K Najumudeen; Andrew D Campbell; Owen J Sansom; Rosa Mistica C Ignacio; Stephanie Naim; Jie Liu; Nelson Russia; Julia Lee; Angela Chou; Amber Johns; Anthony Gill; Estrella Gonzales-Aloy; John Kokkinos; Val Gebski; Nigel Turner; Minoti Apte; Thomas P Davis; Jennifer P Morton; Koroush Haghighi; Australian Pancreatic Cancer Genome Initiative; Phoebe A Phillips
10.1101/2020.07.12.199638 — cancer biology — Posted on 2020-07-12
3176 EGF signaling in bowel carcinoma cells utilizes higher order architectures of EGFR and HER2
Adam Wollman; Charlotte Fournier; Isabel Llorente-Garcia; Oliver Harriman; Alex Hargreaves; Sviatlana Shashkova; Peng Zhou; Djamila Ouret; Jenny Wilding; Ta-Chun Liu; Akihiro Kusumi; Walter F Bodmer; Mark C Leake
10.1101/2020.07.11.198572 — biophysics — Posted on 2020-07-12
3178 Forensic analysis of Soil Microbiomes: Linking Evidence to a Geographic Location
Jill Hager Cocking; Ryan Turley; Viacheslav Y Fofanov; Kimberly Samuels-Crow; Bruce Hungate; Rebecca L Mau; Paul S Keim; J Greg Caporaso; Crystal Hepp
10.1101/2020.07.10.198044 — bioinformatics — Posted on 2020-07-12
3179 Bayesian Decoder Models with a Discriminative Observation Process
Mohammad Reza Rezaei; Alex E. Hadjinicolaou; Sydney S. Cash; Uri Eden; Ali Yousefi
10.1101/2020.07.11.198564 — bioinformatics — Posted on 2020-07-12
3180 A modelling framework for the prediction of the herd-level probability of infection from longitudinal data
Aurélien Madouasse; Mathilde Mercat; Annika van Roon; David Graham; Maria Guelbenzu; Inge Santman Berends; Gerdien van Schaik; Mirjam Nielen; Jenny Frössling; Estelle Ågren; Roger Humphry; Jude Eze; George Gunn; Jörn Gethmann; Simon J. More; Christine Fourichon
10.1101/2020.07.10.197426 — bioinformatics — Posted on 2020-07-12
3181 Agonal factors distort gene-expression patterns in human postmortem brains
Jiacheng Dai; Chao Chen; Rujia Dai; Yu Chen; Yi Jiang; Sihan Liu; Jianghua Tian; Meng Xu; Miao Li; Jiaqi Zhou; Chunyu Liu
10.1101/2020.07.11.198523 — bioinformatics — Posted on 2020-07-12
3183 Normalizing single-cell RNA sequencing data with internal spike-in-like genes
Minfang song; Li Lin; Liye Zhang; Haopeng Wang; Xiaojing Zhao; Jiang Yong
10.1101/2020.07.10.198077 — bioinformatics — Posted on 2020-07-12
3184 PhageAI - Bacteriophage Life Cycle Recognition with Machine Learning and Natural Language Processing
Piotr Tynecki; Arkadiusz Guzinski; Joanna Kazimierczak; Michal Jadczuk; Jaroslaw Dastych; Agnieszka Onisko
10.1101/2020.07.11.198606 — bioinformatics — Posted on 2020-07-12
3189 Crowdsourcing Machine Intelligence Solutions to Accelerate Biomedical Science: Lessons learned from a machine intelligence ideation contest to improve the prediction of 3D domain swapping
Yash Shah; Deepak Sharma; Rakesh Sharma; Sourav Singh; Hrishikesh Thakur; William John; Shamsudheen Marakkar; Prashanth Suravajhala; Vijayaraghava Seshadri Sundararajan; Jayaraman Valadi; Shameer Khader; Ramanathan Sowdhamini
10.1101/2020.07.12.199398 — bioinformatics — Posted on 2020-07-12
3190 DBSCAN-SWA: an integrated tool for rapid prophage detection and annotation
Zhiwei Huang; Fan Zhang; Rui Gan; Fengxia Zhou; Yu Si; Han Yang; Chuangeng Chen; Jiqiu Wu
10.1101/2020.07.12.199018 — bioinformatics — Posted on 2020-07-12
3193 BatchServer: a web server for batch effect evaluation, visualization and correction
Tiansheng Zhu; Guo-Bo Chen; Chunhui Yuan; Rui Sun; Fangfei Zhang; Xiao Yi; Shuigen Zhou; Tiannan Guo
10.1101/2020.03.23.996264 — bioinformatics — Posted on 2020-07-12
3194 ProtTrans: Towards Cracking the Language of Life's Code Through Self-Supervised Deep Learning and High Performance Computing
Ahmed Elnaggar; Michael Heinzinger; Christian Dallago; Ghalia Rihawi; Yu Wang; Llion Jones; Tom Gibbs; Tamas Feher; Christoph Angerer; DEBSINDHU BHOWMIK; Burkhard Rost
10.1101/2020.07.12.199554 — bioinformatics — Posted on 2020-07-12
3195 An orthogonal differentiation platform for genomically programming stem cells, organoids, and bioprinted tissues
Mark Skylar-Scott; Jeremy Huang; Aric Lu; Alex Ng; Tomoya Duenki; Lucy Nam; Sarita Damaraju; George Church; Jennifer A. Lewis
10.1101/2020.07.11.198671 — bioengineering — Posted on 2020-07-12
3196 Sparse parallel independent component analysis and its application to identify linked genomic and gray matter alterations underlying working memory impairment in attention-deficit/hyperactivity disorder
Kuaikuai Duan; Jiayu Chen; Vince D. Calhoun; Wenhao Jiang; Kelly Rootes-Murdy; Gido Schoenmacker; Rogers F. Silva; Barbara Franke; Jan K. Buitelaar; Martine Hoogman; Jaap Oosterlaan; Pieter J Hoekstra; Dirk Heslenfeld; Catharina A Hartman; Emma Sprooten; Alejandro Arias-Vasquez; Jessica A. Turner; Jingyu Liu
10.1101/2020.07.11.198622 — bioengineering — Posted on 2020-07-12
3197 Micro-biogeography greatly matters for competition: Continuous chaotic bioprinting of spatially-controlled bacterial microcosms
Carlos Fernando Ceballos-Gonzalez; Edna Johana Bolivar-Monsalve; Diego Alonso Quevedo-Moreno; Li Lu Lam-Aguilar; Karen Ixchel Borrayo-Montano; Juan Felipe Yee-de Leon; Yu Shrike Zhang; Mario Moises Alvarez; Grissel Trujillo-de Santiago
10.1101/2020.07.12.199307 — bioengineering — Posted on 2020-07-12
3198 Chemoproteomics-Enabled Ligand Screening Yields Covalent RNF114-Based Degraders that Mimic Natural Product Function
Mai Luo; Jessica N Spradlin; Scott M Brittain; Jeffery M McKenna; John A Tallarico; Markus Schirle; Thomas J Maimone; Daniel K Nomura
10.1101/2020.07.12.198150 — biochemistry — Posted on 2020-07-12
3201 Genetic variation in anesthesia success in a New Zealand freshwater snail
Qiudong Song; Richard Magnuson; Marissa Roseman; Joseph Jalinsky; Maurine Neiman
10.1101/2020.07.09.194050 — animal behavior and cognition — Posted on 2020-07-12
3202 Single-nucleus RNA-seq2 reveals a functional crosstalk between liver zonation and ploidy
Maria L Richter; Ioannis K Deligiannis; Anna Danese; Ermira Lleshi; Catalina A Vallejos; Paul Coupland; Maria Colome-Tatche; Celia P. Martinez-Jimenez
10.1101/2020.07.11.193458 — genomics — Posted on 2020-07-12
3203 Identification and characterization of key long non-coding RNAs in the auditory system
Tal Koffler-Brill; Shahar Taiber; Alejandro Anaya; Mor Bordeynik-Cohen; Einat Rosen; Likhitha Kolla; Naama Messika-Gold; Ran Elkon; Matthew W. Kelley; Igor Ulitsky; Karen B. Avraham
10.1101/2020.07.10.197251 — genomics — Posted on 2020-07-12
3204 Template switching mechanism drives the tandem amplification of chromosome 20q11.21 in human pluripotent stem cells
Jason A Halliwell; Duncan Baker; Kim Judge; Michael A Quail; Karen Oliver; Emma Betteridge; Jason Skelton; Peter W Andrews; Ivana Barbaric
10.1101/2020.07.11.198382 — genomics — Posted on 2020-07-12
3205 Impact of genetic susceptibility to multiple sclerosis on the T cell epigenome: proximal and distal effects
Tina Roostaei; Hans-Ulrich Klein; Daniel Felsky; Pia Kivisakk; Sarah M. Connor; Alexandra Kroshilina; Christina Yung; Yiyi Ma; Belinda J. Kaskow; Xiaorong Shao; Brooke Rhead; Jia Liu; Nikolaos Patsopoulos; Lisa F. Barcellos; Howard L. Weiner; Philip L. De Jager
10.1101/2020.07.11.198721 — genomics — Posted on 2020-07-12
3206 Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.
Denis Seyres; Alessandra Cabassi; John J Lambourne; Frances Burden; Samantha Farrow; Harriet McKinney; Joana Batista; Carly Kempster; Maik Pietzner; Oliver Slingsby; Thong Huy Cao; Paulenne Quinn; Luca Stefanucci; Matthew C Sims; Karola Rehnstrom; Claire Adams; Amy Frary; Bekir Erguener; Roman Kreuzhuber; Gabriele Mocciaro; Michael Allison; Simona D'Amore; Albert Koulman; Luigi Grassi; Julian L Griffin; Leong Loke Ng; Adrian Park; David B Savage; Claudia Langenberg; Christoph Bock; Kate Downes; Michele Vacca; Paul DW Kirk; Mattia Frontini
10.1101/2020.03.06.961805 — genomics — Posted on 2020-07-12
3207 A PP2A-Integrator complex fine-tunes transcription by opposing CDK9
Stephin J. Vervoort; Sarah A. Welsh; Jennifer R. Devlin; Elisa Barbieri; Deborah A. Knight; Matteo Costacurta; Izabela Todorovski; Conor J. Kearney; Jarrod J. Sandow; Stefan Bjelosevic; Zheng Fan; Joep H. A. Vissers; Karolina Pavic; Ben P. Martin; Gareth Gregory; Isabella Y. Kong; Edwin D. Hawkins; Simon J. Hogg; Madison J. Kelly; Andrea Newbold; Kaylene J. Simpson; Otto Kauko; Kieran F. Harvey; Michael Ohlmeyer; Jukka Westermarck; Nathanael Gray; Alessandro Gardini; Ricky W. Johnstone
10.1101/2020.07.12.199372 — genomics — Posted on 2020-07-12
3208 The Synaptonemal Complex Central Region Modulates Crossover Pathways and Feedback Control of Meiotic Double-strand Break Formation
Min-su Lee; Mika T Higashide; Hyungseok Choi; Ke Li; Soogil Hong; Kangseok Lee; Akira Shinohara; Miki Shinohara; Keun P Kim
10.1101/2020.07.10.198168 — genetics — Posted on 2020-07-12
3210 Genetics of human gut microbiome composition
Alexander Kurilshikov; Carolina Medina-Gomez; Rodrigo Bacigalupe; Djawad Radjabzadeh; Jun Wang; Ayse Demirkan; Caroline I Le Roy; Juan Antonio Raygoza Garay; Casey Finnicum; Xingrong Liu; Daria Zhernakova; Marc Jan Bonder; Tue H Hansen; Fabian Frost; Malte C Ruhlemann; Williams Turpin; Jee-Young Moon; Han-Na Kim; Kreete Lull; Elad Barkan; Shiraz A Shah; Myriam Fornage; Joanna Szopinska-Tokov; Zachary Wallen; Dmitrii Borisevich; Lars Agreus; Anna Andreasson; Corinna Bang; Larbi Bedrani; Jordana Tzenova Bell; Hans Bisgaard; Michael Boehnke; Dorret I Boomsma; Robert D Burk; Annique Claringbould;
10.1101/2020.06.26.173724 — genetics — Posted on 2020-07-12
3212 Geography is more important than life history in the recent diversification of the tiger salamander complex
Kathryn Michelle Everson; Levi N Gray; Angela G Jones; Nicolette M Lawrence; Mary E Foley; Kelly L Sovacool; Justin D Kratovil; Scott Hotaling; Paul M Hime; Andrew Storfer; Gabriela Parra-Olea; X Aguilar-Miguel; Eric M O'Neill; Luis Zambrano; H Bradley Shaffer; David W Weisrock
10.1101/2020.07.10.197624 — evolutionary biology — Posted on 2020-07-12
3213 Quantum aspects of evolution: a contribution toward evolutionary explorations of genotype networks via quantum walks
Diego Santiago-Alarcon; Horacio Tapia-McClung; Sergio Adrian Lerma-Hernandez; Salvador E Venegas-Andraca
10.1101/2020.07.10.197657 — evolutionary biology — Posted on 2020-07-12
3214 Genomic Evidences Support an Independent History of Grapevine Domestication in the Levant
Aviad Sivan; Oshrit Rahimi; Mali Salmon-Divon; Ehud Weiss; Elyashiv Drori; Sariel Hubner
10.1101/2020.07.11.198358 — evolutionary biology — Posted on 2020-07-12
3216 A framework to quantify phenotypic and genotypic parallel evolution
Maddie E James; Wilkinson J Melanie; Henry L North; Jan Engelstaedter; Daniel Ortiz-Barrientos
10.1101/2020.02.05.936450 — evolutionary biology — Posted on 2020-07-12
3221 Nursery habitat use by juvenile blue crabs in created and natural marshes
Donna Marie Bilkovic; Robert E Isdell; David Stanhope; Kory T Angstadt; Kirk J Havens; Randolph M Chambers
10.1101/2020.07.10.197830 — ecology — Posted on 2020-07-12
3224 Better tired than lost: turtle ant trail networks favor coherence over shortest paths
Arjun Chandrasekhar; James A. R. Marshall; Cortnea Austin; Saket Navlakha; Deborah M Gordon
10.1101/714410 — ecology — Posted on 2020-07-12
3225 Cyanate - a low abundant but actively cycled nitrogen compound in soil
Maria Mooshammer; Wolfgang Wanek; Stephen H. Jones; Andreas Richter; Michael Wagner
10.1101/2020.07.12.199737 — ecology — Posted on 2020-07-12
3226 Reconstruction and analysis of the transmission network of African swine fever in People's Republic of China, August 2018-September 2019
Andrey R. Akhmetzhanov; Sung-mok Jung; Hyojung Lee; Natalie M. Linton; Yichi Yang; Baoyin Yuan; Hiroshi Nishiura
10.1101/2020.07.12.199760 — ecology — Posted on 2020-07-12
3227 Chromatin Topology And The Timing Of Enhancer Function At The HoxD Locus
Edgardo Rodriguez-Carballo; Lucille Lopez-Delisle; Andrea Willemin; Leonardo Beccari; Sandra Gitto; Benedicte Mascrez; Denis Duboule
10.1101/2020.07.12.199109 — developmental biology — Posted on 2020-07-12
3228 Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak.
Kenzo Ivanovitch; Pablo Soro-Barrio; Probir Chakravarty; Rebecca A Jones; S. Neda Mousavy Gharavy; Despina Stamataki; Julien Delile; James C Smith; James Briscoe
10.1101/2020.07.12.198994 — developmental biology — Posted on 2020-07-12
3229 Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor
Yi Kuang; Anna Pyo; Natanel Eafergan; Brittany Cain; Lisa M. Gutzwiller; Ofri Axelrod; Ellen K. Gagliani; Matthew T Weirauch; Raphael Kopan; Rhett Kovall; David Sprinzak; Brian Gebelein
10.1101/2020.07.12.199422 — developmental biology — Posted on 2020-07-12
3230 The changing mouse embryo transcriptome at whole tissue and single-cell resolution
Peng He; Brian A Williams; Diane Trout; Georgi K Marinov; Henry Amrhein; Libera Berghella; Say-Tar Goh; Ingrid Plajzer-Frick; Veena Afzal; Len A Pennacchio; Diane E Dickel; Axel Visel; Bing Ren; Ross C Hardison; Yu Zhang; Barbara J Wold
10.1101/2020.06.14.150599 — developmental biology — Posted on 2020-07-12
3232 Hematopoietic Stem and Progenitor Cell Aging is Initiated at Middle Age Through Decline in Local Insulin-Like Growth Factor 1 (IGF1)
Kira Young; Elizabeth Eudy; Rebecca Bell; Matthew Loberg; Tim Stearns; Lars Velten; Simon Haas; Jennifer Trowbridge
10.1101/2020.07.11.198846 — cell biology — Posted on 2020-07-12
3236 A TRADE-OFF BETWEEN RESISTANCE TO INFECTION AND REPRODUCTION IN PRIMATE EVOLUTION
Sumnima Singh; Jessica A. Thompson; Sebastian Weis; Daniel Sobral; Mauro Truglio; Bahtiyar Yilmaz; Sofia Rebelo; Silvia Cardoso; Erida Gjini; Gabriel Nunez; Miguel P. Soares
10.1101/2020.07.10.186742 — immunology — Posted on 2020-07-12
3237 Imaging Renal Ultrastructure using a Fast and Simple Optical Clearing and Swelling Protocol
David Unnersjoe-Jess; Linus Butt; Martin Hoehne; Anna Witasp; Lucas Kuehne; Peter F Hoyer; Jaakko Patrakka; Paul T Brinkkoetter; Annika Wernerson; Bernhard Schermer; Thomas Benzing; Lena Scott; Hjalmar Brismar; Hans Blom
10.1101/2020.07.10.196733 — pathology — Posted on 2020-07-12
3239 scMET: Bayesian modelling of DNA methylation heterogeneity at single-cell resolution
Chantriolnt-Andreas Kapourani; Ricard Argelaguet; Guido Sanguinetti; Catalina A. Vallejos
10.1101/2020.07.10.196816 — bioinformatics — Posted on 2020-07-12
3240 Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq): A versatile and ultra-sensitive UMI-based NGS library preparation technology, for use with cfDNA and cfRNA.
Thomas L Dunwell; Simon C Dailey; Jihang Yu; Philipp W Becker; Sarah Scaife; Susan D Richman; Henry M Wood; Hayley Slaney; Daniel Bottomley; Xiangsheng Yang; Hui Xiao; Anine L Ottestad; Sissel G. F. Wahl; Bjørn H Grønberg; Hong Y Dai; Guoliang Fu
10.1101/2020.07.10.152405 — genomics — Posted on 2020-07-12
3241 Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors
Wenhan Chen; Yang Wu; Zhili Zheng; Ting Qi; Peter M Visscher; Zhihong Zhu; Jian Yang
10.1101/2020.07.09.196535 — genetics — Posted on 2020-07-12
3242 Harnessing the power of eDNA metabarcoding for the detection of deep-sea fishes
Beverly McClenaghan; Nicole Fahner; David Cote; Julek Chawarski; Avery McCarthy; Hoda Rajabi; Greg Singer; Mehrdad Hajibabaei
10.1101/2020.07.10.197012 — ecology — Posted on 2020-07-12
3243 Creating Red Light-Controlled Protein Dimerization Systems as Genetically Encoded Actuators with High Specificity
Zhimin Huang; Zengpeng Li; Xiao Zhang; Runze Dong; Shoukai Kang; Li Sun; Xiaonan Fu; David Vaisar; Kurumi Watanabe; Liangcai Gu
10.1101/2020.07.09.174003 — synthetic biology — Posted on 2020-07-11
3244 The genotype-phenotype landscape of an allosteric protein
Drew S Tack; Peter D Tonner; Abe Pressman; Nathanael D Olson; Sasha F Levy; Eugenia F Romantseva; Nina Alperovich; Olga Vasilyeva; David Ross
10.1101/2020.07.10.197574 — synthetic biology — Posted on 2020-07-11
3247 EGF signaling in bowel carcinoma cells utilizes higher order architectures of EGFR and HER2
Adam Wollman; Charlotte Fournier; Isabel Llorente-Garcia; Oliver Harriman; Alex Hargreaves; Sviatlana Shashkova; Peng Zhou; Djamila Ouret; Jenny Wilding; Ta-Chun Liu; Akihiro Kusumi; Walter F Bodmer; Mark C Leake
10.1101/2020.07.11.198572 — biophysics — Posted on 2020-07-12
3248 Modelling cell guidance and curvature control in evolving biological tissues
Solene G.D. Hegarty-Cremer; Matthew J Simpson; Thomas L. Andersen; Pascal R Buenzli
10.1101/2020.07.10.197020 — biophysics — Posted on 2020-07-12
3249 Viscoelastic relaxation of collagen networks provides a self-generated directional cue during collective migration
Andrew G Clark; Ananyo Maitra; Cécile Jacques; Anthony Simon; Carlos Pérez-González; Xavier Trepat; Raphaël Voituriez; Danijela Matic Vignjevic
10.1101/2020.07.11.198739 — biophysics — Posted on 2020-07-12
3251 Evidence accumulation determines conscious access
Michael Pereira; Pierre Megevand; Mi Xue Tan; Wenwen Chang; Shuo Wang; Ali Rezai; Margitta Seeck; Marco Corniola; Shahan Momjian; Fosco Bernasconi; Olaf Blanke; Nathan Faivre
10.1101/2020.07.10.196659 — neuroscience — Posted on 2020-07-11
3252 The DNA methyltransferase 1 (DNMT1) acts on neurodegeneration by modulating proteostasis-relevant intracellular processes
Cathrin Bayer; Georg Pitschelatow; Nina Hannemann; Jenice Linde; Julia Reichard; Daniel Pensold; Geraldine Zimmer-Bensch
10.1101/2020.07.10.197442 — neuroscience — Posted on 2020-07-11
3254 Entrainment of network activity by closed-loop microstimulation in healthy ambulatory rats
Alberto Averna; Page Hayley; Maxwell D. Murphy; Jimmy Nguyen; Stefano Buccelli; Federico Barban; Randolph J. Nudo; Michela Chiappalone; David J. Guggenmos
10.1101/2020.07.10.196725 — neuroscience — Posted on 2020-07-11
3255 Nogo-A Beyond the RhoA/ROCK Pathway - Novel Components of Intracellular Nogo-A Signaling Cascades
Martina A. Maibach; Ester Piovesana; Julia Kaiser; Mea M. Holm; Zorica Ristic; Michael Maurer; Martina E. Schwab
10.1101/2020.07.10.197368 — neuroscience — Posted on 2020-07-11
3256 Cortical propagation as a biomarker for recovery after stroke
Gloria Cecchini; Alessandro Scaglione; Anna Letizia Allegra Mascaro; Curzio Checcucci; Emilia Conti; Ihusan Adam; Duccio Fanelli; Roberto Livi; Francesco Saverio Pavone; Thomas Kreuz
10.1101/2020.07.10.197509 — neuroscience — Posted on 2020-07-11
3258 Associations of Mitochondrial Genomic Variation with Corticobasal Degeneration, Progressive Supranuclear Palsy, and Neuropathological Tau Measures
Rebecca R Valentino; Nikoleta Tamvaka; Michael G Heckman; Patrick W Johnson; Alexandra I Soto-Beasley; Ronald L Walton; Shunsuke Koga; Ryan J Uitti; Zbigniew K Wszolek; Dennis W Dickson; Owen A Ross
10.1101/2020.07.10.196097 — neuroscience — Posted on 2020-07-11
3259 Long vs short-term synaptic learning rules after optogenetic spike-timing-dependent plasticity
Margarita Anisimova; Bas van Bommel; J. Simon Wiegert; Marina Mikhaylova; Thomas G. Oertner; Christine E. Gee
10.1101/863365 — neuroscience — Posted on 2020-07-11
3260 Efficient coding of natural scene statistics predicts discrimination thresholds for grayscale textures
Tiberiu Tesileanu; Mary M Conte; John J Briguglio; Ann M Hermundstad; Jonathan D Victor; Vijay Balasubramanian
10.1101/2019.12.11.872994 — neuroscience — Posted on 2020-07-11
3262 A CRISPR-Cas9-engineered mouse model for GPI anchor deficiency mirrors human phenotype and shows hippocampal synaptic dysfunctions.
Miguel Rodriguez de los Santos; Marion Rivalan; Friederike S. David; Alexej Knaus; Alexander Stumpf; Laura Moreno Velasquez; Anne Voigt; Karl Schilling; Daniele Mattei; Melissa Long; Guido Vogt; Lars Wittler; Bernd Timmermann; Peter N. Robinson; Denise Horn; Stefan Mundlos; Uwe Kornak; Dietmar Schmitz; York Winter; Peter Michael Krawitz
10.1101/2020.04.20.050591 — neuroscience — Posted on 2020-07-11
3263 Modeling the hemodynamic response function using EEG-fMRI data during eyes-open resting-state conditions and motor task execution
Prokopis C Prokopiou; Alba Xifra-Porxas; Michalis Kassinopoulos; Marie-Helene Boudrias; Georgios D Mitsis
10.1101/2020.06.29.178483 — neuroscience — Posted on 2020-07-11
3264 The effect of parietal stimulation on hippocampal-cortical rsFC and episodic memory is associated with fractional anisotropy in multiple stimulation site pathways.
Michael V Freedberg; Catherine Cunningham; Cynthia M Fioriti; Jorge Dorado Murillo; Jack A Reeves; Paul A Taylor; Joelle Sarlls; Eric M A Wassermann
10.1101/2020.07.09.195172 — neuroscience — Posted on 2020-07-11
3265 GREATER EMPATHIC ABILITIES AND THEIR CORRELATION WITH RESTING STATE BRAIN CONNECTIVITY IN PSYCHOTHERAPISTS COMPARED TO NON-PSYCHOTHERAPISTS
Víctor Enrique Olalde-Mathieu; Federica Sassi; Azalea Reyes-Aguilar; Roberto E Mercadillo; Sarael Alcauter; Fernando A Barrios
10.1101/2020.07.01.182998 — neuroscience — Posted on 2020-07-11
3269 Functional specialization of the medial temporal lobes in human recognition memory: dissociating effects of hippocampal vs parahippocampal damage.
Georgios P.D. Argyropoulos; Carola Dell'Acqua; Emily Butler; Clare Loane; Adriana Roca-Fernandez; Azhaar Almozel; Nikolas Drummond; Carmen Lage-Martinez; Elisa Cooper; Richard N Henson; Christopher R Butler
10.1101/2020.01.25.919423 — neuroscience — Posted on 2020-07-11
3270 Metabolic features of mouse and human retinas: rods vs. cones, macula vs. periphery, retina vs. RPE
Bo Li; Ting Zhang; Wei Liu; Yekai Wang; Rong Xu; Shaoxue Zeng; Rui Zhang; Mark C Gillies; Ling Zhu; Jianhai Du
10.1101/2020.07.10.196295 — neuroscience — Posted on 2020-07-11
3271 ACE2-expressing endothelial cells in aging mouse brain
SU Bin Lim; Valina L. Dawson; Ted M. Dawson; Sung-Ung Kang
10.1101/2020.07.11.198770 — neuroscience — Posted on 2020-07-11
3274 Functional study of the AMD-associated gene TMEM97 in retinal pigmented epithelium using CRISPR interference
Jiang-Hui Wang; Daniel Urrutia-Cabrera; Santiago Mesa Mora; Tu Nguyen; Sandy Hung; Alex W Hewitt; Thomas L Edwards; Raymond CB Wong
10.1101/2020.07.10.198143 — molecular biology — Posted on 2020-07-11
3275 In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
Beata Turoňová; Mateusz Sikora; Christoph Schürmann; Wim J. H. Hagen; Sonja Welsch; Florian E. C. Blanc; Sören von Bülow; Michael Gecht; Katrin Bagola; Cindy Hörner; Ger van Zandbergen; Shyamal Mosalaganti; Andre Schwarz; Roberto Covino; Michael D. Mühlebach; Gerhard Hummer; Jacomine Krijnse Locker; Martin Beck
10.1101/2020.06.26.173476 — molecular biology — Posted on 2020-07-11
3276 A validation scale to determine the readiness of environmental DNA assays for routine species monitoring
Bettina Thalinger; Kristy Deiner; Lynsey R. Harper; Helen C. Rees; Rosetta C. Blackman; Daniela Sint; Michael Traugott; Caren S. Goldberg; Kat Bruce
10.1101/2020.04.27.063990 — molecular biology — Posted on 2020-07-11
3277 The absence of C-5 DNA methylation in Leishmania donovani allows DNA enrichment from complex samples
Bart Cuypers; Franck Dumetz; Pieter Meysman; Kris Laukens; Geraldine De Muylder; Jean-Claude Dujardin; Malgorzata Anna Domagalska
10.1101/747063 — molecular biology — Posted on 2020-07-11
3278 Lymphatic type-1 interferon responses are critical for control of systemic reovirus dissemination
Matthew B Phillips; Marcelle Dina Zita; Morgan A Howells; Tiffany Weinkopff; Karl W. Boehme
10.1101/2020.07.11.198267 — microbiology — Posted on 2020-07-11
3281 Surface area-to-volume ratio, not cellular rigidity, determines red blood cell traversal through small capillaries
Arman Namvar; Adam Blanch; Matthew WA Dixon; Olivia Carmo; Boyin Liu; Snigdha Tiash; Oliver Looker; Dean Andrew; Li-Jin Chan; Wai-Hong Tham; Peter Vee Sin Lee; Vijay Rajagopal; Leann Tilley
10.1101/2020.07.11.191494 — microbiology — Posted on 2020-07-11
3282 Aedes aegypti SNAP and a calcium transporter ATPase influence dengue virus dissemination.
Alejandro Marin-Lopez; Junjun Jiang; Yuchen Wang; Yongguo Cao; Tyler MacNeil; Andrew K Hastings; Erol Fikrig
10.1101/2020.07.10.198226 — microbiology — Posted on 2020-07-11
3283 Atribacteria reproducing over millions of years in the Atlantic abyssal subseafloor
Aurele Vuillemin; Sergio Vargas; Omer K Coskun; Robert Pockalny; Richard W Murray; David C Smith; Steven D'Hondt; William D Orsi
10.1101/2020.07.10.198200 — microbiology — Posted on 2020-07-11
3284 A Highly Immunogenic Measles Virus-based Th1-biased COVID-19 Vaccine
Cindy Hoerner; Christoph Schuermann; Arne Auste; Aileen Ebenig; Samada Muraleedharan; Maike Herrmann; Barbara Schnierle; Michael D Muehlebach
10.1101/2020.07.11.198291 — microbiology — Posted on 2020-07-11
3285 Isolation and chacterisation of Klebsiella phages for phage therapy
Eleanor Townsend; Lucy Kelly; Lucy Gannon; George Muscatt; Rhys Dunstan; Slawomir Michniewski; Hari Sapkota; Saija J Kiljunen; Anna Kolsi; Mikael Skurnik; Trevor Lithgow; Andrew D MIllard; Eleanor Jameson
10.1101/2020.07.05.179689 — microbiology — Posted on 2020-07-11
3286 Microbial ecology of Ixodes scapularis from Central Pennsylvania, USA
Joyce M Sakamoto; Gabriel Gabriel Enrique Silva Diaz; Elizabeth Anne Wagner
10.1101/2020.07.11.197335 — microbiology — Posted on 2020-07-11
3288 A simple protein-based SARS-CoV-2 surrogate neutralization assay
Kento T Abe; Zhijie Li; Reuben Samson; Payman Samavarchi-Tehrani; Emelissa J Valcourt; Heidi Wood; Patrick Budylowski; Alan Dupuis; Roxie C Girardin; Bhavisha Rathod; Karen Colwill; Allison McGeer; Samira Mubareka; Jennifer L. Gommerman; Yves Durocher; Mario A Ostrowski; Kathleen McDonough; Michael A. Drebot; Steven J. Drews; James M Rini; Anne-Claude Gingras
10.1101/2020.07.10.197913 — immunology — Posted on 2020-07-11
3290 Polymeric Pathogen-like Particles-Based Combination Adjuvants Elicit Potent Mucosal T Cell Immunity to Influenza A Virus
Brock A Bakke; Randall Toy; Woojong Lee; Pallab Pradhan; Gabriela Vogel; Chandranaik Marinaik; Autumn Larsen; Yoshihiro Kawaoka; Krishnendu A Roy; M Suresh
10.1101/2020.07.10.197749 — immunology — Posted on 2020-07-11
3291 Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS- S and MERS-S pseudotyped particles
Catherine Z. Chen; Miao Xu; Manisha Pradhan; Kirill Gorshkov; Jennifer Petersen; Marco R. Straus; Wei Zhu; Paul Shinn; Hui Guo; Min Shen; Carleen Klumpp-Thomas; Samuel G. Michael; Joshua Zimmerberg; Wei Zheng; Gary R Whittaker
10.1101/2020.07.10.197988 — pharmacology and toxicology — Posted on 2020-07-11
3293 Development of a Notch pathway assay and quantification of functional Notch pathway activity in T-cell acute lymphoblastic leukemia
Kirsten Cante-Barrett; Laurent Holtzer; Henk van Ooijen; Rico Hagelaar; Valentina Cordo; Wim Verhaegh; Anja van de Stolpe; Jules P.P. Meijerink
10.1101/2020.07.10.183731 — cancer biology — Posted on 2020-07-11
3294 Induction of a SALL4-dependency for targeted cancer therapy
Junyu Yang; Chong Gao; Miao Liu; Zhiyuan Chen; Yao-Chung Liu; Junsu Kwon; Jun Qi; Xi Tian; Alicia Stein; Yanjing Liu; Nikki R. Kong; Yue Wu; Shenyi Yin; Jianzhong Xi; Hongbo Luo; Leslie E. Silberstein; Julie A.I. Thoms; Ashwin Unnikrishnan; John E. Pimanda; Daniel Geoffrey Tenen; LI Chai
10.1101/2020.07.10.197434 — cancer biology — Posted on 2020-07-11
3295 4-1BB is a target for immunotherapy in patients with undifferentiated pleomorphic sarcoma
Miriam J Melake; Henry G Smith; David Mansfield; Emma Davies; Magnus T Dillon; Anna C Wilkins; Emmanuel C Patin; Malin Pedersen; Richard Buus; Aisha B Miah; Shane H Zaidi; Khin Thway; Alan A Melcher; Andrew J Hayes; Tim R Fenton; Kevin J Harrington; Martin McLaughlin
10.1101/2020.07.10.197293 — cancer biology — Posted on 2020-07-11
3296 YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer
Federica Lo Sardo; Claudio Pulito; Andrea Sacconi; Etleva Korita; Marius Sudol; Sabrina Strano; Giovanni Blandino
10.1101/2020.07.10.197392 — cancer biology — Posted on 2020-07-11
3297 Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes
Christina Bebber; Emily Thomas; Zhiyi Chen; Jenny Stroh; Ariadne Androulidaki; Anna Schmitt; Michaela Hoehne; Lukas Stueker; Marcel Dammert; Fatma Parmaksiz; Cleidson de Padua Alves; Armin Khonsari; Filippo Beleggia; Martin Sos; Jan Riemer; Julie George; Susanne Brodesser; Roman Thomas; H. Christian Reinhardt; Silvia von Karstedt
10.1101/2020.07.11.198408 — cancer biology — Posted on 2020-07-11
3298 A FIJI Macro for quantifying pattern in extracellular matrix
Esther Wershof; Danielle Park; David J Barry; Robert P Jenkins; Antonio Rullan; Anna Wilkins; Ioannis Roxanis; Kurt I Anderson; Paul A Bates; Erik Sahai
10.1101/867507 — cancer biology — Posted on 2020-07-11
3299 Interest of circulating tumor DNA as a biomarker for canine cancers: illustration in histiocytic sarcoma, oral malignant melanoma and multicentric lymphoma
Anais Prouteau; Jerome Alexandre Denis; Pauline De Fornel; Edouard Cadieu; Thomas Derrien; Camille Kergal; Nadine Botherel; Ronan Ulve; Melanie Rault; Amira Bouzidi; Romain Francois; Laetitia Dorso; Alexandra Lespagnol; Patrick Devauchelle; Jerome Abadie; Catherine Andre; benoit Hedan
10.1101/2020.07.10.189118 — cancer biology — Posted on 2020-07-11
3300 mTORC1 deregulation and increased invasiveness cohere with dispersed endolysosomes in high-grade bladder cancer
Pallavi Mathur; Camilla De Barros Santos; Hugo Lachuer; Bruno Latge; Francois Radvanyi; Bruno Goud; Kristine Schauer
10.1101/2020.07.10.196931 — cancer biology — Posted on 2020-07-11
3301 Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy
Magali Humbert; Kristina Seiler; Severin Mosimann; Vreni Rentsch; Sharon L McKenna; Mario P Tschan
10.1101/2020.01.29.924555 — cancer biology — Posted on 2020-07-11
3302 DNA damage alters nuclear mechanics through chromatin reorganisation.
Alia dos Santos; Alexander W Cook; Rosemarie E Gough; Martin Martin Schilling; Nora Aleida Olszok; Ian Brown; Lin Wang; Jesse Arron; Marisa Luisa Martin-Fernandez; Florian Rehfeldt; Christopher P Toseland
10.1101/2020.07.10.197517 — biophysics — Posted on 2020-07-11
3304 Confronting pitfalls of AI-augmented molecular dynamics using statistical physics
Shashank Pant; Zachary Smith; Yihang Wang; Emad Tajkhorshid; Pratyush Tiwary
10.1101/2020.06.11.146985 — biophysics — Posted on 2020-07-11
3305 A nucleoid-associated protein bends and bridges DNA in a multiplicity of topological states with varying specificity
Sam Yoshua; George Watson; Jamiesson Howard; Victor Velasco-Berrelleza; Mark C Leake; Agnes Noy
10.1101/2020.04.17.047076 — biophysics — Posted on 2020-07-11
3307 Investigation of cell nucleus heterogeneity
Noel Reynolds; Eoin McEvoy; Soham Ghosh; Juan Alberto Panadero Perez; Corey Neu; Patrick McGarry
10.1101/2020.07.08.193854 — biophysics — Posted on 2020-07-11
3308 Molecular recognition at septin interfaces: the switches hold the key
Higor Vinícius Dias Rosa; Diego Antonio Leonardo; Gabriel Brognara; José Brandão-Neto; Humberto D'Muniz Pereira; Ana Paula Ulian Araújo; Richard Charles Garratt
10.1101/2020.07.08.161463 — biophysics — Posted on 2020-07-11
3312 Parallelized engineering of mutational models using piggyBac transposon delivery of CRISPR libraries
Xander Nuttle; Nicholas D. Burt; Benjamin Currall; Mariana Moyses-Oliveira; Kiana Mohajeri; Rachita Yadav; Derek J.C. Tai; James F. Gusella; Michael E. Talkowski
10.1101/2020.07.10.197962 — bioengineering — Posted on 2020-07-11
3313 aNy-way Independent Component Analysis
Kuaikuai Duan; Rogers F Silva; Vince D. Calhoun; Jingyu Liu
10.1101/2020.02.03.930156 — bioengineering — Posted on 2020-07-11
3314 Dual cooperation between HSP70 and the 26S proteasome in co-translational protein quality control
Guiyou Tian; Cheng Hu; Yun Yun; Wensheng Yang; Wolfgang Dubiel; Yabin Cheng; Dieter A Wolf
10.1101/2020.07.10.198036 — biochemistry — Posted on 2020-07-11
3315 Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates
Valentina Rossio; Joao Paulo; Joel Chick; Brad Brasher; Steven Gygi; Randall W King
10.1101/844811 — biochemistry — Posted on 2020-07-11
3317 Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding
Robert W. Newberry; Taylor Arhar; Jean Costello; George C. Hartoularos; Alison M. Maxwell; Zun Zar Chi Naing; Maureen Pittman; Nishith R. Reddy; Daniel M. C. Schwarz; Douglas R. Wassarman; Taia S. Wu; Daniel Barrero; Christa Caggiano; Adam Catching; Taylor B. Cavazos; Laurel S. Estes; Bryan Faust; Elissa A. Fink; Miriam A. Goldman; Yessica K. Gomez; M. Grace Gordon; Laura M. Gunsalus; Nick Hoppe; Maru Jaime-Garza; Matthew C. Johnson; Matthew G. Jones; Andrew F. Kung; Kyle E. Lopez; Jared Lumpe; Calla Martyn; Elizabeth E. McCarthy; Lakshmi E. Miller-Vedam; Erik J. Navarro; Aji Palar; Jenna Pell
10.1101/2020.05.01.072884 — biochemistry — Posted on 2020-07-11
3318 Proposed allosteric inhibitors bind to the ATP site of CK2α
Paul Brear; Darby Ball; Katherine Stott; Sheena D'Arcy; Marko Hyvonen
10.1101/2020.07.07.191353 — biochemistry — Posted on 2020-07-11
3321 Functional and structural basis of extreme non-coding conservation in vertebrate mRNAs
Gun Woo Byeon; Elif Sarinay Cenik; Lihua Jiang; Hua Tang; Rhiju Das; Maria Barna
10.1101/2020.06.29.165878 — genetics — Posted on 2020-07-11
3324 An evolutionary trade-off between parasite virulence and dispersal at experimental invasion fronts
Louise Solveig Noergaard; Giacomo Zilio; Camille Saade; Claire Gougat-Barbera; Matthew D. Hall; Emanuel A. Fronhofer; Oliver Kaltz
10.1101/2020.01.31.928150 — evolutionary biology — Posted on 2020-07-11
3326 Time-resolved comparative molecular evolution of oxygenic photosynthesis
Thomas Oliver; Patricia Sánchez-Baracaldo; Anthony W. Larkum; A. William Rutherford; Tanai Cardona
10.1101/2020.02.28.969766 — evolutionary biology — Posted on 2020-07-11
3328 Disruption of a Hedgehog-Foxf1-Rspo2 Signaling Axis Leads to Tracheomalacia and a Loss of Sox9+ Tracheal Chondrocytes
Talia Nasr; Praneet Chaturvedi; Kunal Agarwal; Jessica L. Kinney; Keziah Daniels; Stephen L Trisno; Vladimir Ustiyan; John M Shannon; James Wells; Debora Sinner; Vladimir V Kalinichenko; Aaron Zorn
10.1101/2020.07.11.198556 — developmental biology — Posted on 2020-07-11
3331 The evolution of Sox gene repertoires and regulation of segmentation in arachnids
Luis Baudouin-Gonzalez; Anna Schoenauer; Amber Harper; Grace Blakeley; Michael Seiter; Saad Arif; Lauren Sumner-Rooney; Steven Russell; Prashant P Sharma; Alistair P McGregor
10.1101/2020.06.04.133389 — developmental biology — Posted on 2020-07-11
3332 Development of conformational BRET biosensors that monitor Ezrin, Radixin and Moesin activation in real-time.
Kevin Leguay; Barbara Decelle; Yu Yan He; Mireille Rogue; hiroyuki kobayashi; Christian Le Gouill; Michel Bouvier; Sebastien Carreno
10.1101/2020.07.10.197707 — cell biology — Posted on 2020-07-11
3333 LOK/SLK kinases and ERM proteins function together to regulate apical morphology and inhibit RhoA signaling
Riasat Zaman; Andrew T Lombardo; Cécile Sauvanet; Raghuvir Viswanatha; Valerie Awad; Locke E Bonomo; David J McDermitt; Anthony P Bretscher
10.1101/2020.07.02.185298 — cell biology — Posted on 2020-07-11
3334 Identification of pathways modulating Vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen
Corinna Jie Hui Goh; Jin Huei Wong; Chadi El Farran; Ban Xiong Tan; Cynthia Coffill; Yuin Han Loh; David Lane; Prakash Arumugam
10.1101/2020.07.11.198911 — cell biology — Posted on 2020-07-11
3336 The Amyloid Structure of Mouse RIPK3 (Receptor Interacting Protein Kinase 3) in Cell Necroptosis
Xialian Wu; Hong Hu; Xingqi Dong; Jing Zhang; Jian Wang; Charles Schwieters; Jing Liu; Guo xiang Wu; Bing Li; Jing yu Lin; Huayi Wang; Junxia Lu
10.1101/2020.07.10.196980 — biochemistry — Posted on 2020-07-11
3337 Reference data based insights expand understanding of human metabolomes
Julia M Gauglitz; Wout Bittremieux; Candace L Williams; Kelly C Weldon; Morgan W Panitchpakdi; Francesca Di Ottavio; Christine M Aceves; Elizabeth Brown; Nicole C Sikora; Alan K. Jarmusch; Cameron Martino; Anupriya Tripathi; Erfan Sayyari; Justin Shaffer; Roxana Coras; Fernando Vargas; Lindsay DeRight Goldasich; Tara Schwartz; MacKenzie Bryant; Gregory Humphrey; Abigail J. Johnson; Katharina Spengler; Pedro Belda-Ferre; Edgar Diaz; Daniel McDonald; Qiyun Zhu; Dominic S. Nguyen; Emmanuel O. Elijah; Mingxun Wang; Clarisse Marotz; Kate E. Sprecher; Daniela Vargas-Robles; Dana Withrow; Gail Ackerm
10.1101/2020.07.08.194159 — systems biology — Posted on 2020-07-11
3338 Obesity causes irreversible mitochondria failure in visceral adipose tissue despite successful anti-obesogenic lifestyle-based interventions
Alba Gonzalez-Franquesa; Pau Gama-Perez; Marta Kulis; Norma Dahdah; Sonia Moreno-Gomez; Ana Latorre-Pellicer; Rebeca Fernandez-Ruiz; Antoni Aguilar-Mogas; Erika Monelli; Sara Samino; Joan Miro; Gregor Oemer; Xavier Duran; Estrella Sanchez-Rebordelo; Marc Schneeberger; Merce Obach; Joel Montane; Giancarlo Castellano; Vicente Chapaprieta; Lourdes Navarro; Ignacio Prieto; Carlos Castano; Anna Novials; Ramon Gomis; Maria Monsalve; Marc Claret; Mariona Graupera; Guadalupe Soria; Joan Vendrell; Sonia Fernandez-Veledo; Jose Antonio Enriquez; Angel Carracedo; Jose Carlos Perales; Ruben Nogueiras; Laur
10.1101/2020.07.08.194167 — physiology — Posted on 2020-07-11
3339 Human embryonic stem cells-derived dopaminergic neurons transplanted in parkinsonian monkeys recover dopamine levels and motor behavior
Adolfo Lopez-Ornelas; Itzel Escobedo-Avila; Gabriel Ramirez-Garcia; Rolando Lara-Rodarte; Cesar Melendez-Ramirez; Beetsi Urrieta-Chavez; Tonatiuh Barrios-Garcia; Veronica Caceres-Chavez; Xochitl Flores-Ponce; Francia Carmona; Carlos A Reynoso; Carlos Aguilar; Nora E Kerik; Luisa Rocha; Leticia Verdugo-Diaz; Victor Trevino; Jose Bargas; Veronica Ramos-Mejia; Juan Fernandez-Ruiz; Aurelio Campos-Romo; Ivan Velasco
10.1101/2020.07.08.192591 — neuroscience — Posted on 2020-07-11
3340 DIET INFLUENCES PERIPHERAL AMYLOID BETA METABOLISM: A ROLE FOR CIRCULATING INSULIN-LIKE GROWTH FACTOR I
Herrero Labrador Raquel; Angel Trueba-Saiz; Laura Martinez-Rachadell; Estrella Fernandez de Sevilla; Sonia Diaz-Pacheco; Ana M Fernandez; Ignacio Torres Aleman
10.1101/2020.07.09.180265 — neuroscience — Posted on 2020-07-11
3345 Seasonal shifts in the gut microbiome indicate plastic responses to diet in wild geladas
Alice Baniel; Katherine R Amato; Jacinta C Beehner; Thore J Bergman; Arianne Mercer; Rachel F Perlman; Lauren Petrullo; Laurie Reitsema; Sierra Sams; Amy Lu; Noah Snyder-Mackler
10.1101/2020.07.07.192336 — evolutionary biology — Posted on 2020-07-08
3347 The diverging evolutionary history of opsin genes in Diptera
Roberto Feuda; Matthew Goulty; Nicola Zadra; Tiziana Gasparetti; Ezio Rosato; Nicola Segata; Annapaola Rizzoli; Davide Pisani; Lino Ometto; Omar Rota Stabelli
10.1101/2020.06.29.177931 — evolutionary biology — Posted on 2020-07-08
3351 Genome-wide macroevolutionary signatures of key innovations in butterflies colonizing new host plants
Rémi Allio; Benoit Nabholz; Stefan Wanke; Guillaume Chomicki; Oscar A. Pérez-Escobar; Adam M. Cotton; Anne-Laure Clamens; Gaël J. Kergoat; Felix A.H. Sperling; Fabien L. Condamine
10.1101/2020.07.08.193086 — evolutionary biology — Posted on 2020-07-09
3353 A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages
Simon Dellicour; Keith Durkin; Samuel L. Hong; Bert Vanmechelen; Joan Martí-Carreras; Mandev S. Gill; Cécile Meex; Sébastien Bontems; Emmanuel André; Marius Gilbert; Conor Walker; Nicola De Maio; Nuno R. Faria; James Hadfield; Marie-Pierre Hayette; Vincent Bours; Tony Wawina-Bokalanga; Maria Artesi; Guy Baele; Piet Maes
10.1101/2020.05.05.078758 — evolutionary biology — Posted on 2020-07-09
3356 Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping
Kerry A Geiler-Samerotte; Shuang Li; Charalampos Lazaris; Austin Taylor; Naomi Ziv; Chelsea Ramjeawan; Annalise B Paaby; Mark L Siegal
10.1101/700716 — evolutionary biology — Posted on 2020-07-09
3357 Simple phenotypic tests to improve accuracy in screening chromosomal and plasmid-mediated colistin resistance in gram-negative bacilli
Fernando Pasteran; Diego Danze; Alejandra Menocal; Carla Cabrera; Ignacio Castillo; Ezequiel Albornoz; Celeste Lucero; Melina Rapoport; Paola Ceriana; Alejandra Corso
10.1101/2020.07.06.190850 — microbiology — Posted on 2020-07-08
3358 An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction
Leo Hanke; Laura Vidakovics Perez; Daniel J. Sheward; Hrishikesh Das; Tim Schulte; Ainhoa Moliner-Morro; Martin Corcoran; Adnane Achour; Gunilla B. Karlsson Hedestam; B. Martin Hällberg; Ben Murrell; Gerald M. McInerney
10.1101/2020.06.02.130161 — microbiology — Posted on 2020-07-08
3359 Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity
Collin D. Heer; Daniel J. Sanderson; Lynden S. Voth; Yousef M.O. Alhammad; Mark S. Schmidt; Samuel A.J. Trammell; Stanley Perlman; Michael S. Cohen; Anthony R. Fehr; Charles Brenner
10.1101/2020.04.17.047480 — microbiology — Posted on 2020-07-08
3361 Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures
Roberto Melero; Carlos Oscar S. Sorzano; Brent Foster; José-Luis Vilas; Marta Martínez; Roberto Marabini; Erney Ramírez-Aportela; Ruben Sanchez-Garcia; David Herreros; Laura del Caño; Patricia Losana; Yunior C. Fonseca-Reyna; Pablo Conesa; Daniel Wrapp; Pablo Chacon; Jason S. McLellan; Hemant D. Tagare; Jose-Maria Carazo
10.1101/2020.07.08.191072 — microbiology — Posted on 2020-07-08
3366 Unconventional ER to Endosomal Trafficking by a Retroviral Protein
Wendy Kaichun Xu; Yongqiang Gou; Mary M. Lozano; Jaquelin P. Dudley
10.1101/2020.07.07.192815 — microbiology — Posted on 2020-07-08
3367 In vivo structural characterization of the whole SARS-CoV-2 RNA genome identifies host cell target proteins vulnerable to re-purposed drugs
Lei Sun; Pan Li; Xiaohui Ju; Jian Rao; Wenze Huang; Shaojun Zhang; Tuanlin Xiong; Kui Xu; Xiaolin Zhou; Lili Ren; Qiang Ding; Jianwei Wang; Qiangfeng Cliff Zhang
10.1101/2020.07.07.192732 — microbiology — Posted on 2020-07-08
3368 Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus
Federico Cocozza; Ester Piovesana; Nathalie Névo; Xavier Lahaye; Julian Buchrieser; Olivier Schwartz; Nicolas Manel; Mercedes Tkach; Clotilde Théry; Lorena Martin-Jaular
10.1101/2020.07.08.193672 — microbiology — Posted on 2020-07-08
3370 Expansion Microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid
Eloïse Bertiaux; Aurélia C Balestra; Lorène Bournonville; Mathieu Brochet; Paul Guichard; Virginie Hamel
10.1101/2020.07.08.192328 — microbiology — Posted on 2020-07-08
3373 Identification of the unwinding region in the Clostridioides difficile chromosomal origin of replication
Ana M. Oliveira Paiva; Erika van Eijk; Annemieke H. Friggen; Christoph Weigel; Wiep Klaas Smits
10.1101/2020.07.08.193532 — microbiology — Posted on 2020-07-08
3374 Complete Genome Sequence of the Polysaccharide-Degrading Rumen Bacterium Pseudobutyrivibrio xylanivorans MA3014
Nikola Palevich; Paul H. Maclean; William J. Kelly; Sinead C. Leahy; Jasna Rakonjac; Graeme T. Attwood
10.1101/2020.07.08.194233 — microbiology — Posted on 2020-07-08
3375 GrgA controls Chlamydia trachomatis growth and development by regulating expression of transcription factors Euo and HrcA
Wurihan Wurihan; Yi Zou; Alec M. Weber; Korri Weldon; Yehong Huang; Zheng Gong; Zhongzi Lou; Samantha Sun; Chengsheng Zhu; Xiang Wu; Jizhang Zhou; Yaqun Wang; Zhao Lai; Huizhou Fan
10.1101/2020.07.08.194431 — microbiology — Posted on 2020-07-08
3376 A single-dose live-attenuated YF17D-vectored SARS-CoV2 vaccine candidate
Lorena Sanchez Felipe; Thomas Vercruysse; Sapna Sharma; Ji Ma; Viktor Lemmens; Dominique van Looveren; Mahadesh Prasad Arkalagud Javarappa; Robbert Boudewijns; Bert Malengier-Devlies; Suzanne F. Kaptein; Laurens Liesenborghs; Carolien De Keyzer; Lindsey Bervoets; Madina Rasulova; Laura Seldeslachts; Sander Jansen; Michael Bright Yakass; Osbourne Quaye; Li-Hsin Li; Xin Zhang; Sebastiaan ter Horst; Niraj Mishra; Lotte Coelmont; Christopher Cawthorne; Koen Van Laere; Ghislain Opdenakker; Greetje Van de Velde; Birgit Weynand; Dirk E. Teuwen; Patrick Matthys; Johan Neyts; Hendrik Jan Thibaut; Kai D
10.1101/2020.07.08.193045 — microbiology — Posted on 2020-07-09
3377 Molecular architecture of the SARS-CoV-2 virus
Hangping Yao; Yutong Song; Yong Chen; Nanping Wu; Jialu Xu; Chujie Sun; Jiaxing Zhang; Tianhao Weng; Zheyuan Zhang; Zhigang Wu; Linfang Cheng; Danrong Shi; Xiangyun Lu; Jianlin Lei; Max Crispin; Yigong Shi; Lanjuan Li; Sai Li
10.1101/2020.07.08.192104 — microbiology — Posted on 2020-07-09
3378 Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease
Joseph W. Golden; Curtis R. Cline; Xiankun Zeng; Aura R. Garrison; Brian D. Carey; Eric M. Mucker; Lauren E. White; Joshua D. Shamblin; Rebecca L. Brocato; Jun Liu; April M. Babka; Hypaitia B. Rauch; Jeffrey M. Smith; Bradley S. Hollidge; Collin Fitzpatrick; Catherine V. Badger; Jay W. Hooper
10.1101/2020.07.09.195230 — microbiology — Posted on 2020-07-09
3379 Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiota
Kathy N. Lam; Peter Spanogiannopoulos; Paola Soto-Perez; Margaret Alexander; Matthew J. Nalley; Jordan E. Bisanz; Feiqiao B. Yu; Peter J. Turnbaugh
10.1101/2020.07.09.193847 — microbiology — Posted on 2020-07-09
3381 Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B
Michael J. Mansfield; Benjamin J-M Tremblay; Ji Zeng; Xin Wei; Harold Hodgins; Jay Worley; Lynn Bry; Min Dong; Andrew C. Doxey
10.1101/2020.07.09.194449 — microbiology — Posted on 2020-07-09
3382 Limited genetic diversity of blaCMY-2-containing IncI1-pST12 plasmids from Enterobacteriaceae of human and broiler chicken origin in the Netherlands
Evert den Drijver; Joep J.J.M. Stohr; Jaco J. Verweij; Carlo Verhulst; Francisca C. Velkers; Arjan Stegeman; Marjolein F.Q. Kluytmans-van den Bergh; Jan A.J.W. Kluytmans; i-4-1-Health Study Group
10.1101/2020.07.09.195461 — microbiology — Posted on 2020-07-09
3384 Activity throughout the lichen phylogeny indicates a focus on regulation of specialized metabolites
Ludmila V. Roze; Maris Laivenieks; Kristi Gdanetz; John E. Linz; Alan M. Fryday; Frances Trail
10.1101/2020.07.09.195743 — microbiology — Posted on 2020-07-09
3387 Pili allow dominant marine cyanobacteria to avoid sinking and evade predation
Maria del Mar Aguilo-Ferretjans; Rafael Bosch; Richard J. Puxty; Mira Latva; Vinko Zadjelovic; Audam Chhun; Despoina Sousoni; Marco Polin; David J. Scanlan; Joseph A. Christie-Oleza
10.1101/2020.07.09.194837 — microbiology — Posted on 2020-07-09
3388 Understanding the impact of preprocessing pipelines on neuroimaging cortical surface analyses
Nikhil Bhagwat; Amadou Barry; Erin W. Dickie; Shawn T. Brown; Gabriel A. Devenyi; Koji Hatano; Elizabeth DuPre; Alain Dagher; M. Mallar Chakravarty; Celia M. T. Greenwood; Bratislav Misic; David N. Kennedy; Jean-Baptiste Poline
10.1101/2020.05.22.100180 — bioinformatics — Posted on 2020-07-08
3391 Automated identification of small drug molecules for Hepatitis C virus through a novel programmatic tool and extensive Molecular Dynamics studies of select drug candidates
Rafal Madaj; Akhil Sanker; Ben Geoffrey A S; Host Antony David; Shubham Verma; Judith Gracia; Ayodele Ifeoluwa Faleti; Abdulbasit Haliru Yakubu
10.1101/2020.07.07.192518 — bioinformatics — Posted on 2020-07-08
3396 Explainable AI reveals key changes in skin microbiome associated with menopause, smoking, aging and skin hydration
Anna Paola Carrieri; Niina Haiminen; Sean Maudsley-Barton; Laura-Jayne Gardiner; Barry Murphy; Andrew Mayes; Sarah Paterson; Sally Grimshaw; Martyn Winn; Cameron Shand; Will Rowe; Stacy Hawkins; Ashley MacGuire-Flanagan; Jane Tazzioli; John Kenny; Laxmi Parida; Michael Hoptroff; Edward O. Pyzer-Knapp
10.1101/2020.07.02.184713 — bioinformatics — Posted on 2020-07-08
3397 De Novo Mutational Signature Discovery in Tumor Genomes using SparseSignatures
Avantika Lal; Keli Liu; Robert Tibshirani; Arend Sidow; Daniele Ramazzotti
10.1101/384834 — bioinformatics — Posted on 2020-07-08
3399 Pregnancy data enable identification of relevant biomarkers and a partial prognosis of autism at birth
Hugues Caly; Hamed Rabiei; Perrine Coste-Mazeau; Sebastien Hantz; Sophie Alain; Jean-Luc Eyraud; Thierry Chianea; Catherine Caly; David Makowski; Nouchine Hadjikhani; Eric Lemonnier; Yehezkel Ben-Ari
10.1101/2020.07.08.192989 — bioinformatics — Posted on 2020-07-09
3401 A comprehensive benchmarking of WGS-based structural variant callers
Varuni Sarwal; Sebastian Niehus; Ram Ayyala; Sei Chang; Angela Lu; Nicholas Darci-Maher; Russell Littman; Emily Wesel; Jacqueline Castellanos; Rahul Chikka; Margaret G. Distler; Eleazar Eskin; Jonathan Flint; Serghei Mangul
10.1101/2020.04.16.045120 — bioinformatics — Posted on 2020-07-09
3403 CATA: a comprehensive chromatin accessibility database for cancer
Jianyuan Zhou; Xuecang Li; Jiaxin Chen; Taisong Li; Weijie Zhan; Jianmei Zhao; Meng Li; Zhengmin Yu; Rui Yu; Haiying Zou; Wangkai Fang; Qiuyu Wang; Jianjun Xie
10.1101/2020.05.16.099325 — bioinformatics — Posted on 2020-07-09
3410 Multiple Haplotype Reconstruction from Allele Frequency Data
Marta Pelizzola; Merle Behr; Housen Li; Axel Munk; Andreas Futschik
10.1101/2020.07.09.191924 — bioinformatics — Posted on 2020-07-10
3413 Predicting cell health phenotypes using image-based morphology profiling
Gregory P. Way; Maria Kost-Alimova; Tsukasa Shibue; William F. Harrington; Stanley Gill; Federica Piccioni; Tim Becker; William C. Hahn; Anne E. Carpenter; Francisca Vazquez; Shantanu Singh
10.1101/2020.07.08.193938 — bioinformatics — Posted on 2020-07-10
3415 Screening predictors of weight loss: an Integromics Approach
Joel Correa da Rosa; Jose O. Aleman; Jason Mohabir; Yupu Liang; Jan L Breslow; Peter R. Holt
10.1101/2020.07.06.188284 — bioinformatics — Posted on 2020-07-10
3416 PTM-Shepherd: analysis and summarization of post-translational and chemical modifications from open search results
Daniel J Geiszler; Andy T Kong; Dmitry M Avtonomov; Fengchao Yu; Felipe da Veiga Leprevost; Alexey I Nesvizhskii
10.1101/2020.07.08.192583 — bioinformatics — Posted on 2020-07-10
3417 Genomic Mutations and Changes in Protein Secondary Structure and Solvent Accessibility of SARS-CoV-2 (COVID-19 Virus)
Thanh Thi Nguyen; Pubudu N. Pathirana; Thin Nguyen; Henry Nguyen; Asim Bhatti; Dinh C. Nguyen; Dung Tien Nguyen; Ngoc Duy Nguyen; Douglas Creighton; Mohamed Abdelrazek
10.1101/2020.07.10.171769 — bioinformatics — Posted on 2020-07-10
3418 COCOA: Coordinate covariation analysis of epigenetic heterogeneity
John T. Lawson; Jason P. Smith; Stefan Bekiranov; Francine E Garrett-Bakelman; Nathan C. Sheffield
10.1101/2020.07.09.195289 — bioinformatics — Posted on 2020-07-10
3420 GRIDSS2: harnessing the power of phasing and single breakends in somatic structural variant detection
Daniel L Cameron; Jonathor Baber; Charles Shale; Jose Espejo Valle-Inclan; Nicolle Besselink; Edwin Cuppen; Peter Priestley; Anthony T Papenfuss
10.1101/2020.07.09.196527 — bioinformatics — Posted on 2020-07-10
3422 Improved characterisation of clinical text through ontology-based vocabulary expansion
Luke T Slater; William Bradlow; Simon Ball; Robert Hoehndorf; Georgios V Gkoutos
10.1101/2020.07.10.197541 — bioinformatics — Posted on 2020-07-10
3429 Aedes albopictus (Skuse) susceptibility status to agrochemical-insecticides used in durian planting systems in southern Thailand
Sakda Ratisupakorn; Sokchan Lorn; Nsa Dada; Aran Ngampongsai; Pawit Chaivisit; Wanapa Ritthison; Krajana Tainchum
10.1101/2020.07.09.194746 — zoology — Posted on 2020-07-10
3432 An integrated analysis of myeloid cells identifies gaps in in vitro models of in vivo biology
Nadia Rajab; Paul W Angel; Yidi Deng; Jennifer Gu; Vanta Jameson; Mariola Kurowska-Stolarska; Simon Milling; Chris M Pacheco; Matt Rutar; Andrew L Laslett; Kim Anh Lê Cao; Jarny Choi; Christine A Wells
10.1101/719237 — systems biology — Posted on 2020-07-08
3436 Error propagation in constraint-based modeling of Chinese hamster ovary cells
Diana Széliová; Dmytro Iurashev; David E Ruckerbauer; Gunda Koellensperger; Nicole Borth; Michael Melcher; Jürgen Zanghellini
10.1101/2020.07.09.195594 — systems biology — Posted on 2020-07-10
3438 Single strain control of microbial consortia
Alex J.H. Fedorec; Behzad D. Karkaria; Michael Sulu; Chris P Barnes
10.1101/2019.12.23.887331 — synthetic biology — Posted on 2020-07-08
3439 Robust bidirectional communication between electronics and an engineered multi-functional microbial community
Jessica L. Terrell; Tanya Tschirhart; Justin P. Jahnke; Kristina Stephens; Yi Liu; Hong Dong; Margaret M. Hurley; Maria Pozo; Ryan McKay; Chen Yu Tsao; Hsuan-Chen Wu; Gary Vora; Gregory F. Payne; Dimitra N. Stratis-Cullum; William E. Bentley
10.1101/2020.07.08.194043 — synthetic biology — Posted on 2020-07-08
3440 Production of benzylglucosinolate by engineering and optimizing the biosynthetic pathway in Saccharomyces cerevisiae
Cuiwei Wang; Christoph Crocoll; Christina Spuur Nødvig; Uffe Hasbro Mortensen; Sidsel Ettrup Clemmensen; Barbara Ann Halkier
10.1101/2020.07.08.193391 — synthetic biology — Posted on 2020-07-09
3441 AL-PHA beads: bioplastic-based protease biosensors for global health applications
Richard J. R. Kelwick; Alexander J. Webb; Yizhou Wang; Amelie Heliot; Fiona Allan; Aidan M. Emery; Michael R. Templeton; Paul S. Freemont
10.1101/2020.06.18.159921 — synthetic biology — Posted on 2020-07-09
3442 Synthetic promoter based azide biosensor toolkit to advance chemical-biology
Chandra Kanth Bandi; Kyle S. Skalenko; Ayushi Agrawal; Neelan Sivaneri; Margaux Thiry; Shishir P.S. Chundawat
10.1101/2020.07.08.193060 — synthetic biology — Posted on 2020-07-09
3443 Genetic manipulation of the optical refractive index in living cells
Junko Ogawa; Yoko Iwata; Nina U Tonnu; Chitra Gopinath; Ling Huang; Sachihiko Itoh; Ryoko Ando; Atsushi Miyawaki; Inder M Verma; Gerald M Pao
10.1101/2020.07.09.196436 — synthetic biology — Posted on 2020-07-09
3448 Evidence of selection, adaptation and untapped diversity in Vietnamese rice landraces
Janet Higgins; Bruno Santos; Tran Dang Khanh; Khuat Huu Trung; Tran Duy Duong; Nguyen Thi Phuong Doai; Nguyen Truong Khoa; Dang Thi Thanh Ha; Nguyen Thuy Diep; Kieu Thi Dung; Cong Nguyen Phi; Tran Thi Thuy; Nguyen Thanh Tuan; Hoang Dung Tran; Nguyen Thanh Trung; Hoang Thi Giang; Ta Kim Nhung; Cuong Duy Tran; Son Vi Lang; La Tuan Nghia; Nguyen Van Giang; Tran Dang Xuan; Anthony Hall; Sarah Dyer; Le Huy Ham; Mario Caccamo; Jose De Vega
10.1101/2020.07.07.191981 — plant biology — Posted on 2020-07-08
3449 Parallel evolution of UbiA superfamily proteins into aromatic O-prenyltransferases in plants
Ryosuke Munakata; Alexandre Olry; Tomoya Takemura; Kanade Tatsumi; Takuji Ichino; Cloé Villard; Joji Kageyama; Tetsuya Kurata; Masaru Nakayasu; Florence Jacob; Takao Koeduka; Hirobumi Yamamoto; Eiko Moriyoshi; Tetsuya Matsukawa; Jeremy Grosjean; Célia Krieger; Akifumi Sugiyama; Masaharu Mizutani; Frédéric Bourgaud; Alain Hehn; Kazufumi Yazaki
10.1101/2020.07.07.192757 — plant biology — Posted on 2020-07-08
3450 ConnecTF: A platform to build gene networks by integrating transcription factor-target gene interactions
M.D. Brooks; C.-L. Juang; M.S. Katari; J.M. Alvarez; A.V. Pasquino; H.-J. Shih; J. Huang; C. Shanks; J. Cirrone; G.M. Coruzzi
10.1101/2020.07.07.191627 — plant biology — Posted on 2020-07-09
3452 The rice bundle sheath produces reactive oxygen species during high light stress via NADPH oxidase
Haiyan Xiong; Lei Hua; Ivan Reyna-Llorens; Yi Shi; Kun-Ming Chen; Nicholas Smirnoff; Johannes Kromdijk; Julian M. Hibberd
10.1101/2020.07.06.189381 — plant biology — Posted on 2020-07-09
3453 ConnecTF: A platform to build gene networks by integrating transcription factor-target gene interactions
M.D. Brooks; C.-L. Juang; M.S. Katari; J.M. Alvarez; A.V. Pasquino; H.-J. Shih; J. Huang; C. Shanks; J. Cirrone; G.M. Coruzzi
10.1101/2020.07.07.191627 — plant biology — Posted on 2020-07-09
3454 Several geranylgeranyl diphosphate synthase isoforms supply metabolic substrates for carotenoid biosynthesis in tomato
M. Victoria Barja; Miguel Ezquerro; Gianfranco Diretto; Igor Florez-Sarasa; Elisenda Feixes; Alessia Fiore; Rumyana Karlova; Alisdair R. Fernie; Jules Beekwilder; Manuel Rodriguez-Concepcion
10.1101/2020.07.08.194076 — plant biology — Posted on 2020-07-09
3457 Developing a method for real-time visualization of cellulase activity
Pallavi Kumari; Tali Sayas; Patricia Bucki; Sigal Brown Miyara; Maya Kleiman
10.1101/2020.07.09.193177 — plant biology — Posted on 2020-07-10
3458 Rubisco proton production drives the elevation of CO2 within condensates and carboxysomes
Benedict M. Long; Britta Förster; Sacha B. Pulsford; G. Dean Price; Murray R. Badger
10.1101/2020.07.08.125609 — plant biology — Posted on 2020-07-10
3459 A transcriptional regulatory circuit for the photosynthetic acclimation of microalgae to carbon dioxide limitation
Olga Blifernez-Klassen; Hanna Berger; Birgit Gerlinde Katharina Mittmann; Viktor Klassen; Louise Schelletter; Tatjana Buchholz; Thomas Baier; Maryna Soleimani; Lutz Wobbe; Olaf Kruse
10.1101/2020.07.09.195545 — plant biology — Posted on 2020-07-10
3460 The rice plastidial phosphorylase participates directly in both sink and source processes
Kaan Koper; Seon-Kap Hwang; Magnus Wood; Salvinder Singh; Asaph Cousins; Helmut Kirchhoff; Thomas W. Okita
10.1101/2020.07.09.191585 — plant biology — Posted on 2020-07-10
3461 A formin-mediated cell wall- plasma membrane- cytoskeleton continuum is required for symbiotic infections in Medicago truncatula
Pengbo Liang; Clara Schmitz; Beatrice Lace; Franck Anicet Ditengou; Jean Keller; Cyril Libourel; Pierre-Marc Delaux; Thomas Ott
10.1101/2020.07.10.197160 — plant biology — Posted on 2020-07-10
3462 Identification of parallel pH-and zeaxanthin-dependent quenching of excess energy in LHCSR3 in Chlamydomonas reinhardtii
Julianne M Troiano; Federico Perozeni; Raymundo Moya; Luca Zuliani; Kwangryul Baek; EonSeon Jin; Stefano Cazzaniga; Matteo Ballottari; Gabriela S Schlau-Cohen
10.1101/2020.07.10.197483 — plant biology — Posted on 2020-07-10
3464 The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment
Séverine Lamon; Aimee Morabito; Emily Arentson-Lantz; Olivia Knowles; Grace Elizabeth Vincent; Dominique Condo; Sarah Alexander; Andrew Garnham; Douglas Paddon-Jones; Brad Aisbett
10.1101/2020.03.09.984666 — physiology — Posted on 2020-07-09
3465 Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced hypertension and kidney injury
Catalina Sierra-Ramos; Silvia Velazquez-Garcia; Ayse G. Keskus; Arianna Vastola-Mascolo; Ana E. Rodríguez-Rodríguez; Sergio Luis-Lima; Guadalberto Hernández; Juan F. Navarro-González; Esteban Porrini; Ozlen Konu; Diego Alvarez de la Rosa
10.1101/2020.07.08.191874 — physiology — Posted on 2020-07-09
3471 Pesticide exposure and adverse health effects associated with farm work in Northern Thailand
Chanese A. Forté; Justin Colacino; Katelyn Polemi; Andrea Guytingco; Nicholas J. Peraino; Siripond Jindaphong; Tharinya Kaviya; Judy Westrick; Rick Neitzel; Kowit Nambunmee
10.1101/549618 — pharmacology and toxicology — Posted on 2020-07-09
3473 Development of nano-emulsions based on Ayapana triplinervis for the control of Aedes aegypti larvae
Alex Bruno Lobato Rodrigues; Rosany Martins Lopes; Érica Menezes Rabelo; Rosana Tomazi; Lizandra Lima Santos; Lethícia Barreto Brandão; Cleidjane Gomes Faustino; Ana Luzia Ferreira Farias; Cleydson Breno Rodrigues dos Santos; Patrick de Castro Cantuária; Allan Kardec Ribeiro Galardo; Sheylla Susan Moreira da Silva de Almeida
10.1101/2020.07.09.194985 — pharmacology and toxicology — Posted on 2020-07-09
3474 Low-dose dioxin exposure during pregnancy and lactation increases susceptibility to diet-induced diabetes in dams
Myriam P Hoyeck; Rayanna C Merhi; Hannah Blair; C Duncan Spencer; Mikayla A Payant; Diana I Martin Alfonso; Melody Zhang; Melissa J Chee; Jennifer E Bruin
10.1101/2020.07.09.195552 — pharmacology and toxicology — Posted on 2020-07-10
3475 Chronic high glyphosate exposure delays individual worker bee (Apis mellifera L.) development under field conditions
Richard Odemer; Abdulrahim T. Alkassab; Gabriela Bischoff; Malte Frommberger; Anna Wernecke; Ina Patrizia Wirtz; Jens Pistorius; Franziska Odemer
10.1101/2020.07.08.194530 — pharmacology and toxicology — Posted on 2020-07-10
3478 Knockout of Cyp26a1 and Cyp26b1 during post-natal life causes reduced lifespan, dermatitis, splenomegaly and systemic inflammation in mice
Jessica M Snyder; Guo Zhong; Cathryn Hogarth; Weize Huang; Traci Topping; Jeffrey LaFrance; Laura Palau; Lindsay C Czuba; Michael Griswold; Gabriel Ghiaur; Nina Isoherranen
10.1101/2020.07.09.196170 — pathology — Posted on 2020-07-09
3482 Naturalistic coding of working memory in primate prefrontal cortex
Megan Roussy; Rogelio Luna; Lyndon Duong; Benjamin Corrigan; Roberto A. Gulli; Ramon Nogueira; Ruben Moreno-Bote; Adam J. Sachs; Lena Palaniyappan; Julio C. Martinez-Trujillo
10.1101/2020.06.19.162446 — neuroscience — Posted on 2020-07-08
3484 Plasma neurofilament light protein correlates with diffusion tensor imaging metrics in frontotemporal dementia
Spotorno Nicola; Lindberg Olof; Nilsson Christer; Landqvist Waldö Maria; van Westen Danielle; Nilsson Karin; Vestberg Susanna; Englund Elisabet; Henrik Zetterberg; Kaj Blennow; Jimmy Lätt; Nilsson Markus; Wahlund Lars-Olof; Santillo Alexander
10.1101/2020.07.08.193151 — neuroscience — Posted on 2020-07-08
3485 Mesoscale brain dynamics reorganizes and stabilizes during learning
Yaroslav Sych; Aleksejs Fomins; Leonardo Novelli; Fritjof Helmchen
10.1101/2020.07.08.193334 — neuroscience — Posted on 2020-07-08
3487 Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex
Stephen D. Glasgow; Edwin W. Wong; Ian V. Beamish; Kevin Lancon; Julien Gibon; Philippe Séguéla; Edward S. Ruthazer; Timothy E. Kennedy
10.1101/2020.07.08.194274 — neuroscience — Posted on 2020-07-08
3488 Optogenetic excitation and inhibition of the subthalamic nucleus (STN) induce opposite motor effects
Adriane Guillaumin [Msc]; Gian Pietro Serra [PhD]; François Georges [PhD]; Åsa Wallén-Mackenzie [PhD]
10.1101/2020.07.08.193359 — neuroscience — Posted on 2020-07-08
3490 Bayesian inference of population prevalence
Robin A. A. Ince; Jim W. Kay; Philippe G. Schyns
10.1101/2020.07.08.191106 — neuroscience — Posted on 2020-07-09
3491 Impairment of methylglyoxal detoxification systems causes mitochondrial dysfunction and schizophrenia-like behavioral deficits
Kazuya Toriumi; Stefano Berto; Shin Koike; Noriyoshi Usui; Takashi Dan; Kazuhiro Suzuki; Mitsuhiro Miyashita; Yasue Horiuchi; Akane Yoshikawa; Yuki Sugaya; Takaki Watanabe; Mai Asakura; Masanobu Kano; Yuki Ogasawara; Toshio Miyata; Masanari Itokawa; Genevieve Konopka; Makoto Arai
10.1101/2020.07.08.192906 — neuroscience — Posted on 2020-07-09
3492 The organizational principles of de-differentiated topographic maps
Peng Liu; Anastasia Chrysidou; Juliane Doehler; Thomas Wolbers; Esther Kuehn
10.1101/2020.07.08.179978 — neuroscience — Posted on 2020-07-09
3493 Improved temporal resolution for mapping brain metabolism using functional PET and anatomical MRI knowledge
Viswanath P. Sudarshan; Shenpeng Li; Sharna D. Jamadar; Gary F. Egan; Suyash P. Awate; Zhaolin Chen
10.1101/2020.07.08.192872 — neuroscience — Posted on 2020-07-09
3496 NREM sleep stages specifically alter dynamical integration of large-scale brain networks
Anjali Tarun; Danyal Wainstein-Andriano; Virginie Sterpenich; Laurence Bayer; Lampros Perogamvros; Mark Solms; Nikolai Axmacher; Sophie Schwartz; Dimitri Van De Ville
10.1101/2020.07.08.193508 — neuroscience — Posted on 2020-07-09
3497 Identifying Causative Mechanisms Linking Early-Life Stress to Psycho-Cardio-Metabolic Multi-Morbidity: The EarlyCause Project
Nicole Mariani; Alessandra Borsini; Charlotte A.M. Cecil; Janine F. Felix; Sylvain Sebert; Annamaria Cattaneo; Esther Walton; Yuri Milaneschi; Guy Cochrane; Clara Amid; Jeena Rajan; Juliette Giacobbe; Yolanda Sanz; Ana Agustí; Tania Sorg; Yann Herault; Jouko Miettunen; Priyanka Parmar; Nadia Cattane; Vincent Jaddoe; Jyrki Lötjönen; Carme Buisan; Miguel A. González Ballester; Gemma Piella; Josep L. Gelpi; Femke Lamers; Brenda WJH Penninx; Henning Tiemeier; Malte von Tottleben; Rainer Thiel; Katharina F. Heil; Marjo-Riitta Järvelin; Carmine Pariante; Isabelle M. Mansuy; Karim Lekadir
10.1101/2020.07.08.181958 — neuroscience — Posted on 2020-07-09
3504 Pharmacodynamic Markers of LRRK2 Inhibition in Biofluids
Shijie Wang; Kaela Kelly; Nathalie Schussler; Sylviane Boularand; Laurent Dubois; Frank Hsieh; Elizabeth Tengstrand; Jonathan M. Brotchie; James B. Koprich; Andrew B. West
10.1101/2020.01.28.923557 — neuroscience — Posted on 2020-07-09
3508 Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction
André Ferreira Castro; Lothar Baltruschat; Tomke Stürner; Amirhoushang Bahrami; Peter Jedlicka; Gaia Tavosanis; Hermann Cuntz
10.1101/2020.07.09.195446 — neuroscience — Posted on 2020-07-10
3509 Thalamic inputs determine functionally distinct gamma bands in mouse primary visual cortex
Nicolò Meneghetti; Chiara Cerri; Elena Tantillo; Eleonora Vannini; Matteo Caleo; Alberto Mazzoni
10.1101/2020.07.09.194811 — neuroscience — Posted on 2020-07-10
3510 Astrocytic modulation of information processing by layer 5 pyramidal neurons of the mouse visual cortex
Dimitri Ryczko; Maroua Hanini-Daoud; Steven Condamine; Benjamin J. B. Bréant; Maxime Fougère; Roberto Araya; Arlette Kolta
10.1101/2020.07.09.190777 — neuroscience — Posted on 2020-07-10
3511 Unravelling the molecular players at the cholinergic efferent synapse of the zebrafish lateral line
Agustín E. Carpaneto Freixas; Marcelo J. Moglie; Tais Castagnola; Lucia Salatino; Sabina Domene; Irina Marcovich; Sofia Gallino; Carolina Wedemeyer; Juan D. Goutman; Paola V. Plazas; Ana Belén Elgoyhen
10.1101/2020.07.09.196246 — neuroscience — Posted on 2020-07-10
3512 Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal Synapses
Swarna Pandian; Jian-Ping Zhao; Yasunobu Murata; Fernando J. Bustos; Cansu Tunca; Ramiro D. Almeida; Martha Constantine-Paton
10.1101/2020.07.08.180679 — neuroscience — Posted on 2020-07-10
3515 Topographic deep artificial neural networks reproduce the hallmarks of the primate inferior temporal cortex face processing network
Hyodong Lee; Eshed Margalit; Kamila M. Jozwik; Michael A. Cohen; Nancy Kanwisher; Daniel L. K. Yamins; James J. DiCarlo
10.1101/2020.07.09.185116 — neuroscience — Posted on 2020-07-10
3516 A role for protease activated receptor type 3 (PAR3) in nociception demonstrated through development of a novel peptide agonist
Juliet Mwirigi; Moeno Kume; Shayne N Hassler; Ayesha Ahmad; Pradipta R. Ray; Changyu Jiang; Alexander Chamessian; Nakleh Mseeh; Breya P Ludwig; Benjamin D. Rivera; Marvin T Nieman; Thomas Van de Ven; Ru-Rong Ji; Gregory Dussor; Scott Boitano; Josef Vagner; Theodore J Price
10.1101/2020.07.08.194373 — neuroscience — Posted on 2020-07-10
3517 Aversion encoded in the subthalamic nucleus
Gian Pietro Serra; Adriane Guillaumin; Jérome Baufreton; François Georges; Åsa Wallén-Mackenzie
10.1101/2020.07.09.195610 — neuroscience — Posted on 2020-07-10
3518 Cortical Hierarchy and The Dual Counterstream Architecture.
Julien Vezoli; Loïc Magrou; Xiao-Jing Wang; Kenneth Knoblauch; Martin Vinck; Henry Kennedy
10.1101/2020.04.08.032706 — neuroscience — Posted on 2020-07-10
3519 Fast and sensitive diffuse correlation spectroscopy with highly parallelized single photon detection
Wenhui Liu; Ruobing Qian; Shiqi Xu; Pavan Chandra Konda; Mark Harfouche; Dawid Borycki; Joakim Jonsson; Edouard Berrocal; Colin Cooke; Allie Sinclair; Haoqian Wang; Qionghai Dai; Roarke W. Horstmeyer
10.1101/2020.07.08.193433 — neuroscience — Posted on 2020-07-10
3520 Improving brain age estimates with deep learning leads to identification of novel genetic factors associated with brain aging
Kaida Ning; Ben A Duffy; Meredith Franklin; Will Matloff; Lu Zhao; Nibal Arzouni; Fengzhu Sun; Arthur W Toga
10.1101/2020.07.08.192617 — neuroscience — Posted on 2020-07-10
3523 Muting, not fragmentation, of functional brain networks under general anesthesia
Corson N. Areshenkoff; Joseph Y. Nashed; R. Matthew Hutchison; Melina Hutchison; Ron Levy; Douglas J. Cook; Ravi S. Menon; Stefan Everling; Jason P. Gallivan
10.1101/2020.07.08.188011 — neuroscience — Posted on 2020-07-10
3524 Plasma lipid and liporotein biomarkers in LBC1936: Do they predict general cognitive ability and brain structure?
Sarah E Harris; Stuart Ritchie; Goncalo Correia; Beatriz Jimenez; Chloe Fawns-Ritchie; Alison Pattie; Janie Corley; Susanna Munoz Maniega; Maria Valdes Hernandez; John Starr; Derek Hill; Paul Wren; Mark Bastin; Matthew Lewis; Joanna Wardlaw; Ian Deary
10.1101/2020.07.09.194688 — neuroscience — Posted on 2020-07-10
3526 The Cuban Human Brain Mapping Project population based normative EEG, MRI, and Cognition dataset
Pedro A. Valdes-Sosa; Jorge F. Bosch-Bayard; Lidice Galan Garcia; Maria L Bringas Vega; Eduardo Aubert Vazquez; Samir Das; Trinidad Virues Alba; Cecile Madjar; Zia Mohades; Leigh C. MacIntyre; Chrystine Rogers; Shawn Brown; Lourdes Valdes Urrutia; Iris Rodriguez Gil; Alan C. Evans; Mitchell J. Valdes Sosa
10.1101/2020.07.08.194290 — neuroscience — Posted on 2020-07-10
3527 The effect of parietal stimulation on hippocampal-cortical rsFC and episodic memory is associated with fractional anisotropy in multiple stimulation site pathways.
Michael V Freedberg; Catherine Cunningham; Cynthia M Fioriti; Jorge Dorado Murillo; Jack A Reeves; Paul A Taylor; Joelle Sarlls; Eric M A Wassermann
10.1101/2020.07.09.195172 — neuroscience — Posted on 2020-07-10
3530 Examining the boundary sharpness coefficient as an index of cortical microstructure and its relationship to age and sex in autism spectrum disorder
Emily Olafson; Saashi A Bedford; Gabriel A Devenyi; Raihaan Patel; Stephanie Tullo; Min Tae M Park; Evdokia Anagnostou; Simon Baron-Cohen; Edward T. Bullmore; Lindsay R. Chura; Michael C. Craig; Christine Ecker; Dorothea L. Floris; Rosemary J. Holt; Rhoshel Lenroot; Jason P. Lerch; Michael V. Lombardo; Declan G. M. Murphy; Armin Raznahan; Amber N. V. Ruigrok; Michael D. Spencer; John Suckling; Margot Taylor; The Medical Research Council Autism Imaging Multicentre Study Consortium; Meng-Chuan Lai; M. Mallar Chakravarty
10.1101/2020.07.09.196212 — neuroscience — Posted on 2020-07-10
3535 Opponent thermosensory cells use flexible cross-inhibition for context-dependent choice in Drosophila thermotaxis
Luis Hernandez-Nunez; Alicia Chen; Gonzalo Budelli; Vincent Richter; Anna Rist; Andreas S Thum; Mason Klein; Paul A Garrity; Aravinthan D.T. Samuel
10.1101/2020.07.09.196428 — neuroscience — Posted on 2020-07-10
3536 Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: altered mitochondrial and energy metabolism.
Justyna Okarmus; Jesper F. Havelund; Matias Ryding; Sissel I. Schmidt; Helle Bogetofte; Nils J. Faergeman; Poul Hyttel; Morten Meyer
10.1101/2020.07.10.151902 — neuroscience — Posted on 2020-07-10
3538 The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response
Sarayut Phasuk; Tanita Pairojana; Pavithra Suresh; Shun-Ping Huang; Narawut Pakaprot; Supin Chompoopong; Chee-Hing Yang; Hsueh-Kai Chang; Chien-Chang Chen; Ingrid Liu
10.1101/2020.07.10.196477 — neuroscience — Posted on 2020-07-10
3540 Regulation of GluA1 Phosphorylation by D-amphetamine and Methylphenidate in the Cerebellum
Laura Cutando Ruiz; Emma Puighermanal; Laia Castell; Pauline Tarot; Federica Bertaso; Patricia Bonnavion; Alban de Kerchove d'Exaerde; Elsa Isingrini; Micaela Galante; Glenn Dallerac; Vincent Pascoli; Christian Luscher; Bruno Giros; Emmanuel Valjent
10.1101/2020.07.10.196766 — neuroscience — Posted on 2020-07-10
3541 ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain
Jormay Lim; Ya-Cherng Chu; Chen-Ming Hao; Wei-Hao Liao; Shao-Shien Lin; Sherry Hsu; Hsiao-Hsin Tai; Ya-Chih Chien; Dar-Ming Lai; Wen-Shiang Chen; Chih-Cheng Chen; Jaw-Lin Wang
10.1101/2020.07.10.196634 — neuroscience — Posted on 2020-07-10
3542 Metabolic features of mouse and human retinas: rods vs. cones, macula vs. periphery, retina vs. RPE
Bo Li; Ting Zhang; Wei Liu; Yekai Wang; Rong Xu; Shaoxue Zeng; Rui Zhang; Mark C Gillies; Ling Zhu; Jianhai Du
10.1101/2020.07.10.196295 — neuroscience — Posted on 2020-07-10
3545 Asymmetric representation of aversive prediction errors in Pavlovian threat conditioning
Karita E Ojala; Athina Tzovara; Benedikt A Poser; Antoine Lutti; Dominik R Bach
10.1101/2020.07.10.197665 — neuroscience — Posted on 2020-07-10
3546 Shape-invariant perceptual encoding of dynamic facial expressions across species
Nick Taubert; Michael Stettler; Ramona Siebert; Silvia Spadacenta; Louisa Sting; Peter Dicke; Peter Thier; Martin Giese
10.1101/2020.07.10.195941 — neuroscience — Posted on 2020-07-10
3547 Decoding neural responses to motion-in-depth using EEG
Marc M Himmelberg; Federico G Segala; Ryan T Maloney; Julie M Harris; Alex R Wade
10.1101/661991 — neuroscience — Posted on 2020-07-11
3549 The Time Varying Networks of the Interoceptive Attention and Rest
Ana Y Martínez; Athena Demertzi; Clemens C C Bauer; Zeus Gracia-Tabuenca; Sarael Alcauter; Fernando A Barrios
10.1101/840645 — neuroscience — Posted on 2020-07-11
3551 Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex
Rebecca J. Burge; Andreas Damianou; Anthony J. Wilkinson; Boris Rodenko; Jeremy C. Mottram
10.1101/2020.07.09.195024 — microbiology — Posted on 2020-07-09
3552 Supramolecular assembly of the E. coli LdcI upon acid stress
Matthew Jessop; Clarissa Liesche; Jan Felix; Ambroise Desfosses; Megghane Baulard; Virgile Adam; Angélique Fraudeau; Karine Huard; Grégory Effantin; Jean-Philippe Kleman; Maria Bacia-Verloop; Dominique Bourgeois; Irina Gutsche
10.1101/2020.05.12.090381 — microbiology — Posted on 2020-07-09
3554 A targeted computational screen of the SWEETLEAD database reveals FDA-approved compounds with anti-dengue viral activity
Jasmine Moshiri; David A. Constant; Bowen Liu; Roberto Mateo; Steven Kearnes; Paul Novick; Ritika Prasad; Claude Nagamine; Vijay Pande; Karla Kirkegaard
10.1101/2020.07.09.194993 — microbiology — Posted on 2020-07-09
3556 Adaptation of the Romanomermis culicivorax CCA-adding enzyme to miniaturized armless tRNA substrates
Oliver Hennig; Susanne Philipp; Sonja Bonin; Kévin Rollet; Tim Kolberg; Tina Jühling; Heike Betat; Claude Sauter; Mario Mörl
10.1101/2020.07.07.190959 — molecular biology — Posted on 2020-07-08
3557 Gut microbiota profiles of treatment-naïve adult acute myeloid leukemia patients with neutropenic fever during intensive chemotherapy
Thanawat Rattanathammethee; Pimchanok Tuitemwong; Parameth Thiennimitr; Phinitphong Sarichai; Sarisa Na Pombejra; Pokpong Piriyakhuntorn; Sasinee Hantrakool; Chatree Chai-Adisaksopha; Ekarat Rattarittamrong; Adisak Tantiworawit; Lalita Norasetthada
10.1101/2020.07.09.194910 — microbiology — Posted on 2020-07-09
3558 Improving FnCas12a genome editing by exonuclease fusion
Yongqiang Wu; Qichen Yuan; Yufeng Zhu; Xiang Gao; Jiabao Song; Ziru Yin
10.1101/2020.07.07.191130 — molecular biology — Posted on 2020-07-08
3559 Decline of humoral responses against SARS-CoV-2 Spike in convalescent individuals
Guillaume Beaudoin-Bussières; Annemarie Laumaea; Sai Priya Anand; Jérémie Prévost; Romain Gasser; Guillaume Goyette; Halima Medjahed; Josée Perreault; Tony Tremblay; Antoine Lewin; Laurie Gokool; Chantal Morrisseau; Philippe Bégin; Cécile Tremblay; Valérie Martel-Laferrière; Daniel E. Kaufmann; Jonathan Richard; Renée Bazin; Andrés Finzi
10.1101/2020.07.09.194639 — microbiology — Posted on 2020-07-09
3560 CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains
Hui Huang; Quan Zhu; Adam Jussila; Yuanyuan Han; Bogdan Bintu; Colin Kern; Mattia Conte; Yanxiao Zhang; Simona Bianco; Andrea Chiariello; Miao Yu; Rong Hu; Ivan Juric; Ming Hu; Mario Nicodemi; Xiaowei Zhuang; Bing Ren
10.1101/2020.07.07.192526 — molecular biology — Posted on 2020-07-08
3561 Inactivation analysis of SARS-CoV-2 by specimen transport media, nucleic acid extraction reagents, detergents and fixatives
Stephen Welch; Katherine Davies; Hubert Buczkowski; Nipunadi Hettiarachchi; Nicole Green; Ulrike Arnold; Matthew Jones; Matthew J Hannah; Reah Evans; Christopher Burton; Jane E Burton; Malcolm Guiver; Patricia A Cane; Neil Woodford; Christine B Bruce; Allen D.G Roberts; Marian J Killip
10.1101/2020.07.08.194613 — microbiology — Posted on 2020-07-10
3562 Regulation of the one carbon folate cycle as a shared metabolic signature of longevity
Andrea Annibal; Rebecca George Tharyan; Maribel Fides Schonewolff; Hannah Tam; Christian Latza; Markus Max Karl Auler; Adam Antebi
10.1101/2020.07.07.191544 — molecular biology — Posted on 2020-07-08
3563 Ethanolamine improves colonic barrier functions and inflammatory immunoreactions via shifting microbiome dysbiosis
Jian Zhou; Xia Xiong; Dan Wan; Hongnan Liu; Yirui Shao; Yuliang Wu; Xiali Huang; Changfeng Peng; Pan Huang; Lijun Zou; Yulong Yin
10.1101/2020.07.09.196592 — microbiology — Posted on 2020-07-10
3564 Structural basis of transcription-translation coupling
Chengyuan Wang; Vadim Molodtsov; Emre Firlar; Jason T. Kaelber; Gregor Blaha; Min Su; Richard H. Ebright
10.1101/2020.03.01.972380 — molecular biology — Posted on 2020-07-08
3565 Caspofungin resistance in Candia auris due to mutations in Fks1 with adjunctive role of chitin and key cell wall stress response pathway genes
Dipti Sharma; R A Paul; Arunaloke Chakrabarti; Sanjay Bhattacharya; Rajeev Soman; Shamanth A Shankarnarayan; Dipali Chavan; Shreya singh; Parijit Das; Harsimran Kaur; Anup Ghosh; Shivaprakash M Rudramurthy
10.1101/2020.07.09.196600 — microbiology — Posted on 2020-07-10
3567 Zika virus-like particles bearing covalent dimer of envelope protein protect mice from lethal challenge
Giuditta De Lorenzo; Rapeepat Tandavanitj; Jennifer Doig; Chayanee Setthapramote; Monica Poggianella; Ricardo Sanchez Velazquez; Hannah E. Scales; Julia M. Edgar; Alain Kohl; James M Brewer; Oscar R. Burrone; Arvind H. Patel
10.1101/2020.07.09.196626 — microbiology — Posted on 2020-07-10
3569 Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19
Douglas Ferreira Sales-Medina; Ludmila Rodrigues Pinto Ferreira; Lavinia M. D. Romera; Karolina R Goncalves; Rafael V. C. Guido; Gilles Courtemanche; Marcos S. Buckeridge; Edison Luiz Durigon; Carolina B. Moraes; Lucio Freitas Junior
10.1101/2020.07.09.196337 — microbiology — Posted on 2020-07-10
3570 Mitosis without DNA replication in mammalian somatic cells
Olivier Ganier; Malik Lutzmann; Julien Cau; Isabelle Peiffer; Céline Lemmers; Sihem Zitouni; Charles Theillet; Marcel Méchali
10.1101/2020.07.08.193607 — molecular biology — Posted on 2020-07-09
3572 HIF1α is an essential regulator of steroidogenesis in the adrenal gland
Deepika Watts; Johanna Stein; Ana Meneses; Nicole Bechmann; Ales Neuwirth; Denise Kaden; Anja Krüger; Anupam Sinha; Vasileia Ismini Alexaki; Luis Gustavo Perez-Rivas; Stefan Kircher; Antoine Martinez; Marily Theodoropoulou; Graeme Eisenhofer; Mirko Peitzsch; Ali El-Armouche; Triantafyllos Chavakis; Ben Wielockx
10.1101/2020.07.08.191783 — molecular biology — Posted on 2020-07-09
3576 CRISPR/Cas9-mediated genome editing of Schistosoma mansoni acetylcholinesterase
Hong You; Johannes U. Mayer; Rebecca L. Johnston; Haran Sivakumaran; Shiwanthi Ranasinghe; Vanessa Rivera; Olga Kondrashova; Lambros T. Koufariotis; Xiaofeng Du; Patrick Driguez; Juliet D. French; Nicola Waddell; Mary G. Duke; Wannaporn Ittiprasert; Victoria H. Mann; Paul J. Brindley; Malcolm K. Jones; Donald P. McManus
10.1101/2020.07.08.190694 — molecular biology — Posted on 2020-07-09
3577 Structural inventory of native ribosomal ABCE1-43S pre-initiation complexes
Hanna Kratzat; Timur Mackens-Kiani; Michael Ameismeier; Jingdong Cheng; Estelle Dacheux; Abdelkader Namane; Otto Berninghausen; Micheline Fromont-Racine; Thomas Becker; Roland Beckmann
10.1101/2020.07.09.194902 — molecular biology — Posted on 2020-07-09
3580 Panton Valentine leucocidin enhances community-acquired methicillin-resistant Staphylococcus aureus colonization of the gut
Florence COUZON; Nadege BOURGEOIS-NICOLAOS; Yvonne BENITO; Macarena LARROUDE; Anne TRISTAN; Jean-Philippe Rasigade; Binh An DIEP; Florence DOUCET-POPULAIRE; Francois VANDENESCH
10.1101/2020.07.10.157032 — microbiology — Posted on 2020-07-10
3581 The secreted protein signature of hydatid fluid from pulmonary cystic echinococcosis
Guilherme Brzoskowski dos Santos; Edileuza Danieli da Silva; Eduardo Shigueo Kitano; Maria Eduarda Battistella; Karina Mariante Monteiro; Jeferson Camargo de Lima; Henrique Bunselmeyer Ferreira; Solange Maria de Toledo Serrano; Arnaldo Zaha
10.1101/2020.07.09.195701 — molecular biology — Posted on 2020-07-10
3582 Investigating hospital Mycobacterium chelonae infection using whole genome sequencing and hybrid assembly
CHRISTOPHER GU; Frederic D Bushman; Chunyu Zhao; Casey Hofstaedter; Pablo Tebas; Laurel Glaser; Robert Baldassano; Kyle Bittinger; Lisa Mattei
10.1101/2020.07.10.196873 — microbiology — Posted on 2020-07-10
3583 Sensitive and reproducible determination of clinical HDL proteotypes
Sandra Goetze; Kathrin Frey; Lucia Rohrer; Silvija Radosavljevic; Jan Krützfeldt; Ulf Landmesser; Marco Bueter; Patrick G. A. Pedrioli; Arnold von Eckardstein; Bernd Wollscheid
10.1101/2020.07.09.191312 — molecular biology — Posted on 2020-07-10
3585 A prion accelerates proliferation at the expense of lifespan
David M. Garcia; Edgar A. Campbell; Christopher M. Jakobson; Mitsuhiro Tsuchiya; Acadia DiNardo; Matt Kaeberlein; Daniel F. Jarosz
10.1101/2020.07.10.196584 — molecular biology — Posted on 2020-07-10
3588 Optimization of On-Bead Emulsion Polymerase Chain Reaction Based on Single Particle Analysis
Ryan Ho Ping Siu; Yang Anthony Liu; Kaitlin Hao Yi Chan; Clara Ridzewski; Liane Siu Slaughter; Angela Ruohao Wu
10.1101/2020.07.10.159483 — molecular biology — Posted on 2020-07-10
3589 KLF4 Recruits SWI/SNF to Increase Chromatin Accessibility and Reprogram the Endothelial Enhancer Landscape under Laminar Shear Stress
Jan-Renier AJ Moonen; James Chappell; Minyi Shi; Tsutomu Shinohara; Dan Li; Maxwell R Mumbach; Fan Zhang; Joseph Nasser; Daniel H Mai; Shalina Taylor; Lingli Wang; Ross J Metzger; Howard Y Chang; Jesse M Engreitz; Michael P Snyder; Marlene Rabinovitch
10.1101/2020.07.10.195768 — molecular biology — Posted on 2020-07-10
3591 SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques
Sonny R. Elizaldi; Yashavanth Shaan Lakshmanappa; Jamin W. Roh; Brian A. Schmidt; Timothy D. Carroll; Kourtney D. Weaver; Justin C. Smith; Jesse D. Deere; Joseph Dutra; Mars Stone; Rebecca Lee Sammak; Katherine J. Olstad; J. Rachel Reader; Zhong-Min Ma; Nancy K. Nguyen; Jennifer Watanabe; Jodie Usachaenko; Ramya Immareddy; JoAnn L. Yee; Daniela Weiskopf; Alessandro Sette; Dennis Hartigan-O’Connor; Stephen J. McSorley; John H. Morrison; Nam K. Tran; Graham Simmons; Michael P Busch; Pamela A. Kozlowski; Koen K.A. Van Rompay; Christopher J. Miller; Smita S. Iyer
10.1101/2020.07.07.191007 — immunology — Posted on 2020-07-08
3592 B cells and HSV-specific antibodies respond to HSV-2 reactivation in skin
Emily S. Ford; Anton M. Sholukh; RuthMabel Boytz; Savanna S. Carmack; Alexis Klock; Khamsone Phasouk; Jason Shao; Raabya Rossenkhan; Paul T. Edlefsen; Tao Peng; Christine Johnston; Anna Wald; Jia Zhu; Lawrence Corey
10.1101/2020.07.08.192542 — immunology — Posted on 2020-07-08
3593 Public and private human T cell clones respond differentially to HCMV antigen when boosted by CD3 co-potentiation
Laura R.E. Becher; Wendy K. Nevala; Shari S. Sutor; Megan Abergel; Michele M. Hoffmann; Christopher A. Parks; Larry R. Pease; Adam G. Schrum; Svetomir N. Markovic; Diana Gil
10.1101/2020.07.08.193805 — immunology — Posted on 2020-07-08
3595 The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced exacerbations in cigarette smoke-exposed mice
Magdiel Pérez-Cruz; Bachirou Koné; Rémi Porte; Christophe Carnoy; Julien Tabareau; Pierre Gosset; François Trottein; Jean-Claude Sirard; Muriel Pichavant; Philippe Gosset
10.1101/2020.07.08.193128 — immunology — Posted on 2020-07-08
3596 Activation of STING due to COPI-deficiency
Annemarie Steiner [MSc]; Katja Hrovat Schaale [PhD]; Ignazia Prigione [PhD]; Dominic De Nardo [PhD]; Laura F. Dagley [PhD]; Chien-Hsiung Yu [PhD]; Pawat Laohamonthonkul; Cassandra R. Harapas [BSc]; Michael P. Gantier [PhD]; Marco Gattorno [MD]; Stefano Volpi [MD, PhD]; Sophia Davidson [PhD]; Seth L. Masters [PhD]
10.1101/2020.07.09.194399 — immunology — Posted on 2020-07-09
3597 Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2
Sandra C. A. Nielsen; Fan Yang; Katherine J. L. Jackson; Ramona A. Hoh; Katharina Röltgen; Bryan Stevens; Ji-Yeun Lee; Arjun Rustagi; Angela J. Rogers; Abigail E. Powell; Javaria Najeeb; Ana R. Otrelo-Cardoso; Kathryn E. Yost; Bence Daniel; Howard Y. Chang; Ansuman T. Satpathy; Theodore S. Jardetzky; Peter S. Kim; Taia T. Wang; Benjamin A. Pinsky; Catherine A. Blish; Scott D. Boyd
10.1101/2020.07.08.194456 — immunology — Posted on 2020-07-09
3599 Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency
Shuo Du; Yunlong Cao; Qinyu Zhu; Guopeng Wang; Xiaoxia Du; Runsheng He; Hua Xu; Yinghui Zheng; Bo Wang; Yali Bai; Chenggong Ji; Ayijiang Yisimayi; Qisheng Wang; Ning Gao; X. Sunney Xie; Xiao-dong Su; Junyu Xiao
10.1101/2020.07.09.195263 — immunology — Posted on 2020-07-09
3600 The HLA Ligand Atlas - A resource of natural HLA ligands presented on benign tissues
Ana Marcu; Leon Bichmann; Leon Kuchenbecker; Daniel Johannes Kowalewski; Lena Katharina Freudenmann; Linus Backert; Lena Mühlenbruch; András Szolek; Maren Lübke; Philipp Wagner; Tobias Engler; Sabine Matovina; Jian Wang; Mathias Hauri-Hohl; Roland Martin; Konstantina Kapolou; Juliane Sarah Walz; Julia Velz; Holger Moch; Luca Regli; Manuela Silginer; Michael Weller; Markus W. Löffler; Florian Erhard; Andreas Schlosser; Oliver Kohlbacher; Stefan Stevanović; Hans-Georg Rammensee; Marian Christoph Neidert
10.1101/778944 — immunology — Posted on 2020-07-09
3601 A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system
Kathleen Grabert; Anuj Sehgal; Katharine M. Irvine; Evi Wollscheid-Lengeling; Derya D. Ozdemir; Jennifer Stables; Garry A. Luke; Martin D. Ryan; Antony Adamson; Neil E. Humphreys; Cheyenne J. Sandrock; Rocio Rojo; Veera A. Verkasalo; Werner Mueller; Peter Hohenstein; Allison R. Pettit; Clare Pridans; David A. Hume
10.1101/2020.07.09.196402 — immunology — Posted on 2020-07-09
3602 Intestinal-epithelial LSD1 controls cytoskeletal-mediated cell identity including goblet cell effector responses required for gut inflammatory and infectious diseases
Naveen Parmar; Kyle Burrows; Håvard T. Lindholm; Rosalie T. Zwiggelaar; Mara Martín-Alonso; Madeleine Fosslie; Bruce Vallance; John Arne Dahl; Colby Zaph; Menno J. Oudhoff
10.1101/2020.07.09.186114 — immunology — Posted on 2020-07-10
3603 SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function
Emma S Winkler; Adam L Bailey; Natasha M Kafai; Sharmila Nair; Broc T McCune; Jinsheng Yu; Julie M Fox; Rita E Chen; James T Earnest; Shamus P Keeler; Jon H Ritter; Liang-I Kang; Sarah Dort; Annette Robichaud; Richard Head; Michael J Holtzman; Michael S Diamond
10.1101/2020.07.09.196188 — immunology — Posted on 2020-07-10
3604 Severely ill COVID-19 patients display augmented functional properties in SARS-CoV-2-reactive CD8+ T cells
Anthony Kusnadi; Ciro Ramírez-Suástegui; Vicente Fajardo; Serena J Chee; Benjamin J Meckiff; Hayley Simon; Emanuela Pelosi; Grégory Seumois; Ferhat Ay; Pandurangan Vijayanand; Christian H Ottensmeier
10.1101/2020.07.09.194027 — immunology — Posted on 2020-07-10
3605 Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis
James Brett Case; Paul Rothlauf; Rita E. Chen; Natasha Kafai; Julie M. Fox; Swathi Shrihari; Broc T. McCune; Ian B. Harvey; Brittany Smith; Shamus Keeler; Louis-Marie Bloyet; Emma S Winkler; Michael J. Holtzman; Daved H. Fremont; Sean P. J. Whelan; Michael S. Diamond
10.1101/2020.07.09.196386 — immunology — Posted on 2020-07-10
3606 Which animals are at risk? Predicting species susceptibility to Covid-19
Matthew R Alexander; Clara T. Schoeder; Jacquelyn A. Brown; Charles D. Smart; Christopher W. Moth; John P. Wikswo; John Anthony Capra; Jens Meiler; Wenbiao Chen; Meena S. Madhur
10.1101/2020.07.09.194563 — immunology — Posted on 2020-07-10
3607 SARS-CoV-2 induces activation and diversification of human plasmacytoid pre-dendritic cells.
Fanny Onodi; Lucie Bonnet-Madin; Léa Karpf; Laurent Meertens; Justine Poirot; Jerôme LeGoff; Constance Delaugerre; Ali AMARA; Vassili Soumelis
10.1101/2020.07.10.197343 — immunology — Posted on 2020-07-10
3608 Discriminating Mild from Critical COVID-19 by Innate and Adaptive Immune Single-cell Profiling of Bronchoalveolar Lavages
Els Wauters; Pierre Van Mol; Abhishek D. Garg; Sander Jansen; Yannick Van Herck; Lore Vanderbeke; Ayse Bassez; Bram Boeckx; Bert Malengier-Devlies; Anna Timmerman; Thomas Van Brussel; Tina Van Buyten; Rogier Schepers; Elisabeth Heylen; Dieter Dauwe; Christophe Dooms; Jan Gunst; Greet Hermans; Philippe Meersseman; Dries Testelmans; Jonas Yserbyt; Patrick Matthys; Sabine Tejpar; CONTAGIOUS collaborators; Johan Neyts; Joost Wauters; Junbin Qian; Diether Lambrechts
10.1101/2020.07.09.196519 — immunology — Posted on 2020-07-10
3609 Programming Multifaceted Pulmonary T-Cell Immunity by Combination Adjuvants
M Suresh; Chandranaik Marinaik; Brock Kingstad-Bakke; Woojong Lee; Masato Hatta; Michelle Sonsalla; Autumn Larsen; Brandon Neldner; David Gasper; Ross Kedl; Yoshihiro Kawaoka
10.1101/2020.07.10.197459 — immunology — Posted on 2020-07-10
3612 Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntington’s disease mutations
Sonia Malaiya; Marcia Cortes-Gutierrez; Brian R. Herb; Sydney R. Coffey; Samuel R.W. Legg; Jeffrey P. Cantle; Carlo Colantuoni; Jeffrey B. Carroll; Seth A. Ament
10.1101/2020.07.08.192880 — genomics — Posted on 2020-07-09
3613 Reply: Evidence that APP gene copy number changes reflect recombinant vector contamination
Ming-Hsiang Lee; Christine S Liu; Yunjiao Zhu; Gwendolyn E Kaeser; Richard Rivera; William J Romanow; Yasuyuki Kihara; Jerold Chun
10.1101/730291 — genomics — Posted on 2020-07-09
3615 Aging leads to stochastic loss of silencing at transposons in mammary luminal epithelial cells
Parijat Senapati; Masaru Miyano; Mudaser Basam; Rosalyn W. Sayaman; Amy Leung; Mark A. LaBarge; Dustin E. Schones
10.1101/2020.06.26.170043 — genomics — Posted on 2020-07-09
3616 Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium
Bryan C. Quach; Michael J. Bray; Nathan C. Gaddis; Mengzhen Liu; Teemu Palviainen; Camelia C. Minica; Stephanie Zellers; Richard Sherva; Fazil Aliev; Michael Nothnagel; Kendra A. Young; Jesse A. Marks; Hannah Young; Megan U. Carnes; Yuelong Guo; Alex Waldrop; Nancy Y.A. Sey; Maria T. Landi; Daniel W. McNeil; Dmitriy Drichel; Lindsay A. Farrer; Christina A. Markunas; Jacqueline M. Vink; Jouke-Jan Hottenga; William G. Iacono; Henry R. Kranzler; Nancy L. Saccone; Michael C. Neale; Pamela Madden; Marcella Rietschel; Mary L. Marazita; Matthew McGue; Hyejung Won; Georg Winterer and the German Nicoti
10.1101/2020.01.15.898858 — genomics — Posted on 2020-07-09
3617 The stem rust fungus Puccinia graminis f. sp. tritici induces centromeric small RNAs during late infection that direct genome-wide DNA methylation
Jana Sperschneider; Ashley W. Jones; Jamila Nasim; Bo Xu; Silke Jacques; Narayana M. Upadhyaya; Rohit Mago; Melania Figueroa; Karam B. Singh; Eric A. Stone; Benjamin Schwessinger; Ming-Bo Wang; Jennifer M. Taylor; Peter N. Dodds
10.1101/469338 — genomics — Posted on 2020-07-09
3618 iPromoter-BnCNN: a novel branched CNN based predictor for identifying and classifying sigma promoters
Ruhul Amin; Chowdhury Rafeed Rahman; Sajid Ahmed; Md. Habibur Rahman Sifat; Md Nazmul Khan Liton; Md. Moshiur Rahman; Swakkhar Shatabda
10.1101/2019.12.27.884965 — genomics — Posted on 2020-07-09
3620 Genetic information insecurity as state of the art
Garrett J Schumacher; Sterling Sawaya; Demetrius Nelson; Aaron Hansen
10.1101/2020.07.08.192666 — genomics — Posted on 2020-07-10
3625 Genomic variations in SARS-CoV-2 genomes from Gujarat: Underlying role of variants in disease epidemiology
Madhvi Joshi; Apurvasinh C Puvar; Dinesh Kumar; Afzal Ansari; Maharshi Pandya; Janvi Raval; Zarna Patel; Pinal Trivedi; Monica Gandhi; Labdhi Pandya; Komal Patel; Nitin Savaliya; Snehal Bagatharia; Sachin Kumar; Chaitanya Joshi
10.1101/2020.07.10.197095 — genomics — Posted on 2020-07-10
3626 Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network.
Mathys Grapotte; Manu Saraswat; Chloe Bessiere; Christophe Menichelli; Jordan Ramilowski; Jessica Severin; Yoshihide Hayashizaki; Itoh Masayoshi; Michihira Tagami; Mitsuyoshi Murata; Miki Kojima-Ishiyama; Shohei Noma; Shuhei Noguchi; Takeya Kasukawa; Akira Hasegawa; Harukazu Suzuki; Hiromi Sueki-Nishiyori; Martin Frith; FANTOM consortium; Clement Chatelain; Piero Carninci; Michiel J.L. de Hoon; Wyeth W Wasserman; Laurent Brehelin; Charles Henri Lecellier
10.1101/2020.07.10.195636 — genomics — Posted on 2020-07-10
3627 Quantitative benzimidazole resistance and fitness effects of parasitic nematode beta-tubulin alleles
Clayton M. Dilks; Steffen R. Hahnel; Qicong Sheng; Lijiang Long; Patrick T. McGrath; Erik C. Andersen
10.1101/2020.07.07.191866 — genetics — Posted on 2020-07-08
3629 Gene-based mapping of trehalose biosynthetic pathway genes reveals association with source- and sink-related yield traits in a spring wheat panel
Danilo H. Lyra; Cara A. Griffiths; Amy Watson; Ryan Joynson; Gemma Molero; Alina-Andrada Igna; Keywan Hassani-Pak; Matthew P. Reynolds; Anthony Hall; Matthew J. Paul
10.1101/2020.07.07.192054 — genetics — Posted on 2020-07-08
3632 Family Analysis with Mendelian Imputations
Augustine Kong; Stefania Benonisdottir; Alexander I. Young
10.1101/2020.07.02.185181 — genetics — Posted on 2020-07-08
3634 Whole genome survey of big cats (Genus: Panthera) identifies novel microsatellites of utility in conservation genetic study
Jee Yun Hyun; Puneet Pandey; Kyung Seok Kim; Alvin Chon; Daecheol Jeong; Jong Bhak; Mi-Hyun Yoo; Hey-Kyung Song; Randeep Singh; Mi-Sook Min; Surendra Prakash Goyal; Damdingiin Bayarkhagva; Hang Lee
10.1101/2020.07.08.193318 — genetics — Posted on 2020-07-08
3636 Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila
Bhavatharini Kasinathan; Serafin U. Colmenares; Hannah McConnell; Janet M. Young; Gary H. Karpen; Harmit S. Malik
10.1101/2020.07.08.192740 — genetics — Posted on 2020-07-08
3637 Denisovan introgression has shaped the immune system of present-day Papuans
Davide M. Vespasiani; Guy S. Jacobs; Nicolas Brucato; Murray P. Cox; Irene Gallego Romero
10.1101/2020.07.09.196444 — evolutionary biology — Posted on 2020-07-09
3638 Multi-influential interactions alters behaviour and cognition through six main biological cascades in Down syndrome mouse models
Arnaud Duchon; Maria del Mar Muñiz Moreno; Sandra Martin Lorenzo; Márcia Priscilla Silva de Souza; Claire Chevalier; Valérie Nalesso; Hamid Meziane; Paulo Loureiro de Sousa; Vincent Noblet; Jean-Paul Armspach; Veronique Brault; Yann Herault
10.1101/2020.07.08.193136 — genetics — Posted on 2020-07-08
3639 Convergence in light transmission properties of transparent wing areas in clearwing mimetic butterflies
Charline Pinna; Maëlle Vilbert; Stephan Borensztajn; Willy Daney de Marcillac; Florence Piron-Prunier; Aaron F. Pomerantz; Nipam Patel; Serge Berthier; Christine Andraud; Doris Gomez; Marianne Elias
10.1101/2020.06.30.180612 — evolutionary biology — Posted on 2020-07-09
3640 Improving the informativeness of Mendelian disease-derived pathogenicity scores for common disease
Samuel S. Kim; Kushal K. Dey; Omer Weissbrod; Carla Marquez-Luna; Steven Gazal; Alkes L. Price
10.1101/2020.01.02.890657 — genetics — Posted on 2020-07-09
3641 Oviposition of the mosquito Aedes aegypti in forest and domestic habitats in Africa
Siyang Xia; Hany K. M. Dweck; Joel Lutomiah; Rosemary Sang; Carolyn S. McBride; Noah H. Rose; Diego Ayala; Jeffrey R. Powell
10.1101/2020.07.08.192187 — evolutionary biology — Posted on 2020-07-09
3643 Protein attenuation as a mechanism of robustness to gene duplication in protein complexes
Diana Ascencio; Guillaume Diss; Isabelle Gagnon-Arsenault; Alexandre K Dubé; Alexander DeLuna; Christian R. Landry
10.1101/2020.07.09.195990 — evolutionary biology — Posted on 2020-07-10
3646 A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo
Jasper Che-Yung Chien; Elie Tabet; Kelsey Pinkham; Cintia Carla da Hora; Jason Cheng-Yu Chang; Steven Lin; Christian Elias Badr; Charles Pin-Kuang Lai
10.1101/2020.03.30.015271 — genetics — Posted on 2020-07-09
3647 Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras
Taline D Kazandjian; Daniel Petras; Samuel D Robinson; Jory van Thiel; Harry W Greene; Kevin Arbuckle; Axel Barlow; David A Carter; Roel M Wouters; Gareth Whiteley; Simon C Wagstaff; Ana S Arias; Laura-Oana Albulescu; Anthony von Plettenberg Laing; Cara Hall; Adam Heap; Samuel Penrhyn-Lowe; Christopher V McCabe; Stuart Ainsworth; Ricardo R da Silva; Pieter C Dorrestein; Michael K Richardson; José María Gutiérrez; Juan J Calvete; Robert A Harrison; Irina Vetter; Eivind A B Undheim; Wolfgang Wüster; Nicholas R Casewell
10.1101/2020.07.08.192443 — evolutionary biology — Posted on 2020-07-10
3648 The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high fat diet
Andrew McEwan; Johanna Celene Erickson; Connor Davidson; Jenny Heijkoop; Yvonne Turnbull; Mirela Delibegovic; Chris Murgatroyd; Alasdair MacKenzie
10.1101/2020.07.08.186643 — genetics — Posted on 2020-07-09
3649 Comparison of target enrichment strategies for ancient pathogen DNA
Anja Furtwängler; Judith Neukamm; Lisa Böhme; Ella Reiter; Melanie Vollstedt; Natasha Arora; Pushpendra Singh; Stewart T. Cole; Sascha Knauf; Sébastien Calvignac-Spencer; Ben Krause-Kyora; Johannes Krause; Verena J. Schuenemann; Alexander Herbig
10.1101/2020.07.09.195065 — genetics — Posted on 2020-07-10
3650 Evidence for reduced immune gene diversity and activity during the evolution of termites
Shulin He; Thorben Sieksmeyer; Yanli Che; M. Alejandra Esparza Mora; Petr Stiblik; Ronald Banasiak; Mark C. Harrison; Jan Sobotnik; Zongqing Wang; Paul R. Johnston; Dino P. McMahon
10.1101/2020.07.09.192013 — evolutionary biology — Posted on 2020-07-10
3651 DNA methylation site loss for plasticity-led novel trait genetic fixation
Takafumi Katsumura; Suguru Sato; Kana Yamashita; Shoji Oda; Takashi Gakuhari; Shodai Tanaka; Kazuko Fujitani; Toshiyuki Nishimaki; Tadashi Imai; Yasutoshi Yoshiura; Hirohiko Takeshima; Yasuyuki Hashiguchi; Hiroshi Mitani; Motoyuki Ogawa; Hideaki Takeuchi; Hiroki Oota
10.1101/2020.07.09.194738 — evolutionary biology — Posted on 2020-07-10
3654 A unifying concept of animal breeding programs
Henner Simianer; Amudha Ganesan; Lisa Büttgen; Ngoc-Thuy Ha; Torsten Pook
10.1101/2020.07.08.193201 — genetics — Posted on 2020-07-10
3656 MoBPSweb: A web-based framework to simulate and compare breeding programs
Torsten Pook; Lisa Büttgen; Amudha Ganesan; Ngoc-Thuy Ha; Henner Simianer
10.1101/2020.07.08.193227 — genetics — Posted on 2020-07-10
3657 Phylogeny and biogeography of Ceiba Mill. (Malvaceae, Bombacoideae)
Flavia Fonseca Pezzini; Kyle G. Dexter; Jefferson G. Carvalho-Sobrinho; Catherine A. Kidner; James A. Nicholls; Luciano P. Queiroz; R. Toby Pennington
10.1101/2020.07.10.196238 — evolutionary biology — Posted on 2020-07-10
3659 PathFinder: Bayesian inference of clone migration histories in cancer
Sudhir Kumar; Antonia Chroni; Koichiro Tamura; Maxwell Sanderford; Olumide Oladeinde; Vivian Aly; Tracy Vu; Sayaka Miura
10.1101/2020.07.10.197194 — evolutionary biology — Posted on 2020-07-10
3660 Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans
Kathryn S. Evans; Stefan Zdraljevic; Lewis Stevens; Kimberly Collins; Robyn E. Tanny; Erik C Andersen
10.1101/2020.07.10.196857 — genetics — Posted on 2020-07-10
3661 Host adaptation and microbial competition drive Ralstonia solanacearum phylotype I evolution in South Korea
Maxim Prokchorchik; Ankita Pandey; Hayoung Moon; Wanhui Kim; Hyelim Jeon; Stephen Poole; Cécile Segonzac; Kee Hoon Sohn; Honour C McCann
10.1101/2020.07.10.196865 — evolutionary biology — Posted on 2020-07-10
3662 Age-dependent ribosomal DNA variations and their effect on cellular function in mammalian cells
Eriko Watada; Sihan Li; Yutaro Hori; Katsunori Fujiki; Katsuhiko Shirahige; Toshifumi Inada; Takehiko Kobayashi
10.1101/2020.07.10.196840 — genetics — Posted on 2020-07-10
3664 Altered vertebrae morphology and bone mineralization in a zebrafish model of CHARGE syndrome
Maximilian Breuer; Maximilian Rummler; Charlotte Zaouter; Bettina M Willie; Shunmoogum (Kessen) Patten
10.1101/2020.07.10.197533 — genetics — Posted on 2020-07-11
3665 Acoel single-cell transcriptomics: cell-type analysis of a deep branching bilaterian
Jules Duruz; Cyrielle Kaltenrieder; Peter Ladurner; Rémy Bruggmann; Pedro Martinez; Simon G. Sprecher
10.1101/2020.07.10.196782 — evolutionary biology — Posted on 2020-07-10
3668 Colonization and extinction dynamics and their link to the distribution of European trees at continental scale
Arnaud Guyennon; Björn Reineking; Jonas Dahlgren; Aleksi Lehtonen; Sophia Ratcliffe; Paloma Ruiz-Benito; Miguel A. Zavala; Georges Kunstler
10.1101/748483 — ecology — Posted on 2020-07-08
3669 A new on-line tool for the calculation of bioaccumulation factors of active substances within living organisms: MOSAICBioacc
Aude Ratier; Christelle Lopes; Gauthier Multari; Vanessa Mazerolles; Patrice Carpentier; Sandrine Charles
10.1101/2020.07.07.185835 — ecology — Posted on 2020-07-08
3670 Biodiversity Soup II: A bulk-sample metabarcoding pipeline emphasizing error reduction
Chunyan Yang; Kristine Bohmann; Xiaoyang Wang; Wang Cai; Nathan Wales; Zhaoli Ding; Shyam Gopalakrishnan; Douglas W. Yu
10.1101/2020.07.07.187666 — ecology — Posted on 2020-07-08
3671 DeepForest: A Python package for RGB deep learning tree crown delineation
Ben. G. Weinstein; Sergio Marconi; Mélaine Aubry-Kientz; Gregoire Vincent; Henry Senyondo; Ethan White
10.1101/2020.07.07.191551 — ecology — Posted on 2020-07-08
3672 Quantifying the effects of switchgrass (Panicum virgatum) on deep organic C stocks using natural abundance 14C in three marginal soils
Eric W. Slessarev; Erin E. Nuccio; Karis J. McFarlane; Christina Ramon; Malay Saha; Mary K. Firestone; Jennifer Pett-Ridge
10.1101/2020.07.07.190587 — ecology — Posted on 2020-07-08
3673 Host-associated fungal communities are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome
Xavier A. Harrison; Allan D. McDevitt; Jenny C. Dunn; Sarah Griffiths; Chiara Benvenuto; Richard Birtles; Jean P. Boubli; Kevin Bown; Calum Bridson; Darren Brooks; Samuel S. Browett; Ruth F. Carden; Julian Chantrey; Friederike Clever; Ilaria Coscia; Katie L. Edwards; Natalie Ferry; Ian Goodhead; Andrew Highlands; Jane Hopper; Joseph Jackson; Robert Jehle; Mariane da Cruz Kaizer; Tony King; Jessica M. D. Lea; Jessica L. Lenka; Alexandra McCubbin; Jack McKenzie; Bárbara Lins Caldas de Moraes; Denise B. O’Meara; Poppy Pescod; Richard F. Preziosi; Jennifer K. Rowntree; Susanne Shultz; Matthew J. S
10.1101/2020.07.07.177535 — ecology — Posted on 2020-07-08
3674 An algorithm for quantifying and characterizing misleading trajectories in ecological processes
Christie A. Bahlai; Easton R. White; Julia D. Perrone; Sarah Cusser; Kaitlin Stack Whitney
10.1101/2020.07.07.192211 — ecology — Posted on 2020-07-08
3677 Branching Networks Can Have Opposing Influences on Genetic Variation in Riverine Metapopulations
Ming-Chih Chiu; Bin Li; Kei Nukazawa; Vincent H. Resh; Thaddeus Carvajal; Kozo Watanabe
10.1101/550194 — ecology — Posted on 2020-07-08
3678 Urban living influences the reproductive success of Darwin’s finches in the Galápagos Islands
Johanna A. Harvey; Kiley Chernicky; Shelby R. Simons; Taylor B. Verrett; Jaime A. Chaves; Sarah A. Knutie
10.1101/2020.07.08.193623 — ecology — Posted on 2020-07-09
3680 Trophic cascade driven by behavioural fine-tuning as naïve prey rapidly adjust to a novel predator
Chris J. Jolly; Adam S. Smart; John Moreen; Jonathan K. Webb; Graeme R. Gillespie; Ben L. Phillips
10.1101/856997 — ecology — Posted on 2020-07-09
3685 Unlocking the Predictive Power of Heterogeneous Data to Build an Operational Dengue Forecasting System
Carrie A Manore; Geoffrey Fairchild; Amanda Ziemann; Nidhi Parikh; Katherine Kempfert; Kaitlyn Martinez; Lauren Castro; David Osthus; Amir Siraj; Jessica Conrad; E Nicholas Generous; Sara Del Valle
10.1101/2020.07.08.194019 — ecology — Posted on 2020-07-10
3686 Assessment of endemic northern swamp deer (Rucervus duvaucelii duvaucelii) distribution and identification of priority conservation areas through modeling and field surveys across north India
Shrutarshi Paul; Debanjan Sarkar; Abhilash Patil; Tista Ghosh; Gautam Talukdar; Mukesh Kumar; Bilal Habib; Parag Nigam; Dhananjai Mohan; Bivash Pandav; Samrat Mondol
10.1101/2020.07.09.194803 — ecology — Posted on 2020-07-10
3689 Mechanical transmission of African swine fever virus by Stomoxys calcitrans: insights from a mechanistic model
Timothée Vergne; Mathieu Andraud; Sarah I. Bonnet; Nick De Regge; Marc Desquesnes; Johanna Fite; Florence Etore; Mutien-Marie Garigliani; Ferran Jori; Laetitia Lempereur; Marie-Frédérique Lepotier; Elsa Quillery; Claude Saegerman; Laurence Vial; Emilie Bouhsira
10.1101/2020.07.10.179853 — ecology — Posted on 2020-07-10
3691 Temperature triggers provide quantitative predictions of multi-species fish spawning peaks
Emma S. Choi; Erik Saberski; Tom Lorimer; Cameron Smith; Unduwap Kandage-don; Ronald S. Burton; George Sugihara
10.1101/2020.07.10.196923 — ecology — Posted on 2020-07-10
3692 Beyond a single patch: local and regional processes explain diversity patterns in a seagrass epifaunal metacommunity
Keila A Stark; Patrick L Thompson; Jennifer Yakimishyn; Lynn Lee; Emily M Adamczyk; Margot Hessing-Lewis; Mary I O'Connor
10.1101/482406 — ecology — Posted on 2020-07-10
3695 Single-cell morphometrics reveals ancestral principles of notochord development
Toby G R Andrews; Wolfram Pönisch; Ewa Paluch; Benjamin J Steventon; Elia Benito-Gutierrez
10.1101/2020.07.08.193813 — developmental biology — Posted on 2020-07-08
3697 Epigenetic immune-modulation by Histone Deacetylase Activity (HDAC) of tissue and organ regeneration in Xenopus laevis
Nathalia Pentagna; Felipe Soares dos Santos; Fernanda Martins de Almeida; José Garcia Abreu; Michael Levin; Katia Carneiro
10.1101/2020.02.05.936294 — developmental biology — Posted on 2020-07-09
3700 Air and surface contamination in non-health care settings among 641 environmental specimens of 39 COVID-19 cases
Lei Luo [PhD]; Dan Liu [PhD]; Hao Zhang [MSc]; Zhihao Li [PhD]; Ruonan Zhen [MSc]; Xiru Zhang [PhD]; Huaping Xie [MSc]; Weiqi Song [MSc]; Jie Liu [MSc]; Qingmei Huang [MSc]; Jingwen Liu [MSc]; Xingfen Yang [PhD]; Zongqiu Chen [PhD]; Chen Mao [PhD]
10.1101/2020.07.09.195008 — developmental biology — Posted on 2020-07-09
3701 Widespread retention of ohnologs in key developmental gene families following whole genome duplication in arachnopulmonates
Amber Harper; Luis Baudouin Gonzalez; Anna Schönauer; Michael Seiter; Michaela Holzem; Saad Arif; Alistair P McGregor; Lauren Sumner-Rooney
10.1101/2020.07.10.177725 — developmental biology — Posted on 2020-07-10
3702 Somatic transposition in the Drosophila intestine occurs in active chromatin and is associated with tumor suppressor gene inactivation
Katarzyna Siudeja; Marius van den Beek; Nick Riddiford; Benjamin Boumard; Annabelle Wurmser; Marine Stefanutti; Sonia Lameiras; Allison J Bardin
10.1101/2020.07.10.166629 — developmental biology — Posted on 2020-07-10
3705 Calnexin mediates the maturation of GPI-anchors through ER retention
Xin-Yu Guo; Yi-Shi Liu; Xiao-Dong Gao; Taroh Kinoshita; Morihisa Fujita
10.1101/2020.07.08.192955 — cell biology — Posted on 2020-07-08
3706 Heart Slice Culture System Reliably Demonstrates Clinical Drug-Related Cardiotoxicity
Jessica M. Miller; Moustafa H. Meki; Qinghui Ou; Sharon A. George; Anna Gams; Riham R. E. Abouleisa; Xian-Liang Tang; Brooke M. Ahern; Guruprasad A. Giridharan; Ayman El-Baz; Bradford G. Hill; Jonathan Satin; Daniel J. Conklin; Javid Moslehi; Roberto Bolli; Alexandre J. S. Ribeiro; Igor R. Efimov; Tamer M. A. Mohamed
10.1101/2020.06.12.148197 — cell biology — Posted on 2020-07-08
3707 MARCKS domain phosphorylation regulates the differential interaction of Diacylglycerol Kinase ζ with Rac1, RhoA and Syntrophin
Ryan Ard; Jean-Christian Maillet; Elias Daher; Michael Phan; Radoslav Zinoviev; Robin J. Parks; Stephen H. Gee
10.1101/2020.07.08.194100 — cell biology — Posted on 2020-07-08
3708 Requirement of FLCN tumor suppressor gene for mTORC1-mediated inhibition of TFE3 transcriptional activity
Hua Li; HyoungBin Oh; Benoit Viollet; Laura S. Schmidt; W. Marston Linehan; Vera P. Krymskaya; Seung-Beom Hong
10.1101/2020.07.08.193169 — cell biology — Posted on 2020-07-08
3710 Unravelling the developmental roadmap towards human brown adipose tissue
Stefania Carobbio; Anne-Claire Guenantin; Myriam Bahri; Isabella Samuelson; Floris Honig; Sonia Rodriguez-Fdez; Kathleen Long; Ioannis Kamzolas; Sherine Awad; Dunja Lukovic; Slaven Erceg; Andrew R Bassett; Sasha Mendjan; Ludovic vallier; Barry S Rosen; Davide Chiarugi; Antonio Vidal-Puig
10.1101/2020.07.09.194886 — cell biology — Posted on 2020-07-09
3714 Multi-resolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism
Anthony Yan-Tang Wu; Yun-Chieh Sung; Yen-Ju Chen; Steven Ting-Yu Chou; Vanessa Guo; Jasper Che-Yung Chien; John Jun-Sheng Ko; Alan Ling Yang; Hsi-Chien Huang; Ju-Chen Chuang; Ysuan Wu; Meng-Ru Ho; Maria Ericsson; Wan-Wan Lin; Chantal Hoi Yin Cheung; Hsueh-Fen Juan; Koji Ueda; Yunching Chen; Charles Pin-Kuang Lai
10.1101/2020.03.27.012625 — cell biology — Posted on 2020-07-09
3716 Screening and testing for a suitable untransfected cell line for SARS-CoV-2 studies
Claudia Pommerenke; Ulfert Rand; Cord C. Uphoff; Stefan Nagel; Margarete Zaborski; Vivian Hauer; Maren Kaufmann; Corinna Meyer; Sabine A. Denkmann; Peggy Riese; Kathrin Eschke; Yeonsu Kim; Zeljka Macak Safranko; Ivan-Christian Kurolt; Alemka Markotic; Linda Brunotte; Stephan Ludwig; Luka Cicin-Sain; Laura Steenpaß
10.1101/2020.07.09.195040 — cell biology — Posted on 2020-07-09
3717 Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells
Manish Bodas; Andrew R. Moore; Bharathiraja Subramaniyan; Constantin Georgescu; Jonathan D. Wren; Willard M. Freeman; Brent R. Brown; Jordan P. Metcalf; Matthew S. Walters
10.1101/2020.07.09.195818 — cell biology — Posted on 2020-07-09
3718 Type V Myosin focuses the polarisome and shapes the tip of yeast cells
Alexander Dünkler; Marcin Leda; Jan-Michael Kromer; Joachim Neller; Thomas Gronemeyer; Andrew B. Goryachev; Nils Johnsson
10.1101/2020.07.09.195271 — cell biology — Posted on 2020-07-10
3719 Metabolite patterns in human myeloid hematopoiesis result from lineage-dependent active metabolic pathways
Lars Kaiser; Helga Weinschrott; Isabel Quint; Folker Wenzel; Markus Blaess; Manfred Jung; Matthias Kohl; Hans-Peter Deigner
10.1101/2020.07.09.195156 — cell biology — Posted on 2020-07-10
3721 A single cell atlas of human cornea that defines its development, limbal stem and progenitor cells and the interactions with the limbal niche
Joseph Collin; Rachel Queen; Darin Zerti; Sanja Bojic; Nicky Moyse; Marina Moya-Molina; Chunbo Yang; Gary Reynolds; Rafiqul Hussain; Jonathan M Coxhead; Steven Lisgo; Deborah Henderson; Agatha Joseph; Paul Rooney; Saurabh Ghosh; Che Connon; Muzlifah Haniffa; Francisco Figueiredo; Lyle Armstrong; Majlinda Lako
10.1101/2020.07.09.195438 — cell biology — Posted on 2020-07-10
3723 Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection
Jeonghwan Youk; Taewoo Kim; Kelly V. Evans; Young-Il Jeong; Yongsuk Hur; Seon Pyo Hong; Je Hyoung Kim; Kijong Yi; Su Yeon Kim; Kwon Joong Na; Thomas Bleazard; Ho Min Kim; Natasha Ivory; Krishnaa T. Mahbubani; Kourosh Saeb-Parsy; Young Tae Kim; Gou Young Koh; Byeong-Sun Choi; Young Seok Ju; Joo-Hyeon Lee
10.1101/2020.07.10.194498 — cell biology — Posted on 2020-07-10
3726 An integrative oncogene-dependency map identifies unique vulnerabilities of oncogenic EGFR, KRAS, and RIT1 in lung cancer
Athea Vichas; Naomi T. Nkinsi; Amanda Riley; Phoebe C.R. Parrish; Fujiko Duke; Jenny Chen; Iris Fung; Jacqueline Watson; Matthew Rees; John K. Lee; Federica Piccioni; Emily M. Hatch; Alice H. Berger
10.1101/2020.07.03.187310 — cancer biology — Posted on 2020-07-08
3727 An integrative oncogene-dependency map identifies unique vulnerabilities of oncogenic EGFR, KRAS, and RIT1 in lung cancer
Athea Vichas; Naomi T. Nkinsi; Amanda Riley; Phoebe C.R. Parrish; Fujiko Duke; Jenny Chen; Iris Fung; Jacqueline Watson; Matthew Rees; John K. Lee; Federica Piccioni; Emily M. Hatch; Alice H. Berger
10.1101/2020.07.03.187310 — cancer biology — Posted on 2020-07-08
3729 Dual Functions of SPOP and ERG Dictate Androgen Therapy Responses in Prostate Cancer
Tiziano Bernasocchi; Geniver El Tekle; Marco Bolis; Azzurra Mutti; Arianna Vallerga; Laura P. Brandt; Filippo Spriano; Tanya Svinkina; Marita Zoma; Valentina Ceserani; Anna Rinaldi; Hana Janouskova; Daniela Bossi; Manuela Cavalli; Simone Mosole; Roger Geiger; Ze Dong; Cai-Guang Yang; Domenico Albino; Andrea Rinaldi; Peter Schraml; Simon Linder; Giuseppina M. Carbone; Andrea Alimonti; Francesco Bertoni; Holger Moch; Steven A. Carr; Wilbert Zwart; Marianna Kruithof-de Julio; Mark A. Rubin; Namrata D. Udeshi; Jean-Philippe P. Theurillat
10.1101/2020.07.08.193581 — cancer biology — Posted on 2020-07-08
3730 Evolutionary Action Score of TP53 Mutations: Integrated Clinico-pathologic And Protein Structural Analysis in Myelodysplastic Syndromes
Rashmi Kanagal-Shamanna; Guillermo Montalban-Bravo; Panagiotis Katsonis; Koji Sasaki; Caleb A. Class; Christopher Benton; Elias Jabbour; Kelly S. Chien; Rajyalakshmi Luthra; Carlos E. Bueso-Ramos; Tapan Kadia; Michael Andreeff; Nicholas Short; Naval Daver; Mark J. Routbort; Joseph D. Khoury; Keyur Patel; Irene Ganan-Gomez; Yue Wei; Gautam Borthakur; Farhad Ravandi; Kim-Anh Do; Kelly A. Soltysiak; Olivier Lichtarge; L. Jeffrey Medeiros; Hagop Kantarjian; Guillermo Garcia-Manero
10.1101/2020.07.08.194365 — cancer biology — Posted on 2020-07-08
3731 Gain-of-function CRISPR screens identify tumor-promoting genes conferring melanoma cell plasticity and therapy-resistance
Arthur Gautron; Laura Bachelot; Anaïs M. Quéméner; Sébastien Corre; Marc Aubry; Florian Rambow; Anaïs Paris; Nina Tardif; Héloïse M. Leclair; Cédric Coulouarn; Jean-Christophe Marine; Marie-Dominique Galibert; David Gilot
10.1101/2020.07.08.193102 — cancer biology — Posted on 2020-07-09
3732 Evaluation of nucleosome concentrations in healthy dogs and dogs with cancer
H Wilson-Robles; T Miller; J Jarvis; J Terrell; N Dewsbury; T Kelly; M Herzog; T Bygott; N Hardat; G Michel
10.1101/2020.07.08.193466 — cancer biology — Posted on 2020-07-09
3733 NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells
Ralitsa R. Madsen; James Longden; Rachel G. Knox; Xavier Robin; Franziska Völlmy; Kenneth G. Macleod; Larissa S. Moniz; Neil O. Carragher; Rune Linding; Bart Vanhaesebroeck; Robert K. Semple
10.1101/753830 — cancer biology — Posted on 2020-07-09
3734 NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells
Ralitsa R. Madsen; James Longden; Rachel G. Knox; Xavier Robin; Franziska Völlmy; Kenneth G. Macleod; Larissa S. Moniz; Neil O. Carragher; Rune Linding; Bart Vanhaesebroeck; Robert K. Semple
10.1101/753830 — cancer biology — Posted on 2020-07-09
3735 HIP1 mediates oncogenic transformation and cancer progression through STAT3 signalling
Roheet Bantval Rao; Antonio Ramos-Montoya; Helen Scott; Lorraine Berry; Stefanie Reichelt; Stewart MacArthur; Roslin Russell; David E Neal; Emma Evergren; Ian G Mills
10.1101/2020.07.09.191734 — cancer biology — Posted on 2020-07-09
3736 A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
Stephen Tang; Nebiyou Y. Metaferia; Marina F. Nogueira; Maya K. Gelbard; Sarah Abou Alaiwi; Ji-Heui Seo; Justin H. Hwang; Craig A. Strathdee; Sylvan C. Baca; Jiao Li; Shatha AbuHammad; Xiaoyang Zhang; John G. Doench; William C. Hahn; David Y. Takeda; Matthew L. Freedman; Peter S. Choi; Srinivas R. Viswanathan
10.1101/2020.06.17.156034 — cancer biology — Posted on 2020-07-09
3737 A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
Stephen Tang; Nebiyou Y. Metaferia; Marina F. Nogueira; Maya K. Gelbard; Sarah Abou Alaiwi; Ji-Heui Seo; Justin H. Hwang; Craig A. Strathdee; Sylvan C. Baca; Jiao Li; Shatha AbuHammad; Xiaoyang Zhang; John G. Doench; William C. Hahn; David Y. Takeda; Matthew L. Freedman; Peter S. Choi; Srinivas R. Viswanathan
10.1101/2020.06.17.156034 — cancer biology — Posted on 2020-07-09
3738 Interplay between Desmoglein2 and hypoxia controls metastasis in breast cancer
Po-Hao Chang; Min-Che Chen; Ya-Ping Tsai; Pang-Hung Hsu; Yung-Ming Jeng; Yi-Fang Tsai; Muh-Hwa Yang; Wendy W. Hwang-Verslues
10.1101/790519 — cancer biology — Posted on 2020-07-09
3739 Interplay between Desmoglein2 and hypoxia controls metastasis in breast cancer
Po-Hao Chang; Min-Che Chen; Ya-Ping Tsai; Pang-Hung Hsu; Yung-Ming Jeng; Yi-Fang Tsai; Muh-Hwa Yang; Wendy W. Hwang-Verslues
10.1101/790519 — cancer biology — Posted on 2020-07-09
3742 Relationship between stemness and transcriptionally-inferred PI3K activity in human breast cancer
Ralitsa R. Madsen; Oscar M. Rueda; Xavier Robin; Carlos Caldas; Robert K. Semple; Bart Vanhaesebroeck
10.1101/2020.07.09.195974 — cancer biology — Posted on 2020-07-09
3743 Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor
Luca Iamartino; Taha Elajnaf; Katharina Gall; Jacquelina David; Teresa Manhardt; Petra Heffeter; Michael Grusch; Sophia Derdak; Sabina Baumgartner-Parzer; Martin Schepelmann; Enikö Kallay
10.1101/2020.07.09.195255 — cancer biology — Posted on 2020-07-10
3744 Embryonic Protein NODAL Regulates the Breast Tumour Microenvironment by Reprogramming Cancer-Derived Secretomes
Dylan Dieters-Castator; Paola Marino Dantonio; Matt Piaseczny; Guihua Zhang; Jiahui Liu; Miljan Kuljanin; Stephen Sherman; Michael Jewer; Katherine Quesnel; Eun Young Kang; Martin Köbel; Gabrielle M. Siegers; Andrew Leask; David Hess; Gilles Lajoie; Lynne-Marie Postovit
10.1101/2020.07.09.195842 — cancer biology — Posted on 2020-07-10
3746 Defining the transcriptional landscape of infiltrating immune cells in human and mouse bladder cancer.
Haocheng Yu; John P Sfakianos; Li Wang; Jorge Daza; Matthew D Galsky; Nina Bhardwaj; Oliver Elemento; Bishoy M Faltas; Jun Zhu; David Mulholland
10.1101/2020.07.09.195685 — cancer biology — Posted on 2020-07-10
3747 Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy
Pavan Bachireddy; Elham Azizi; Cassandra Burdziak; Vinhkhang N Nguyen; Christina Ennis; Zi-Ning Choo; Shuqiang Li; Kenneth J Livak; Donna S Neuberg; Robert J Soiffer; Jerome Ritz; Edwin P Alyea; Dana Pe'er; Catherine J Wu
10.1101/2020.07.08.194332 — cancer biology — Posted on 2020-07-10
3748 Bone marrow stromal cells induce an ALDH+ stem cell-like phenotype in AML cells through TGF-β-p38-ALDH2 pathway
Bin Yuan; Fouad El Dana; Stanley Ly; Yuanqing Yan; Vivian Ruvolo; Elizabeth J. Shpall; Marina Konopleva; Michael Andreeff; Venkata Lokesh Battula
10.1101/2020.07.10.197178 — cancer biology — Posted on 2020-07-10
3749 Ral GTPases promote metastasis by controlling biogenesis and organ colonization of exosomes
Shima Ghoroghi; Benjamin Mary; Annabel Larnicol; Annick Klein; Nael Osmani; Ignacio Busnelli; Francois Delalande; Nicodeme Paul; Sebastien Halary; Frederic Gros; Laetitia Fouillen; Anne-Marie Haeberle; Cathy Royer; Coralie Spiegelhalter; Gwennan Andre-Gregoire; Kendelle Murphy; Paul Timpson; Raphael Carapito; Marcel Blot-Chabaud; Julie Gavard; Christine Carapito; Nicolas Vitale; Olivier Lefebvre; Jacky G. Goetz; Vincent Hyenne
10.1101/2020.07.10.196691 — cancer biology — Posted on 2020-07-10
3751 Understanding the Functional Properties of Lipid Heterogeneity in Pulmonary Surfactant Monolayers at the Atomistic Level
Juho Liekkinen; Berta de Santos Moreno; Riku O. Paananen; Ilpo Vattulainen; Luca Monticelli; Jorge Bernardino de la Serna; Matti Javanainen
10.1101/2020.07.07.191569 — biophysics — Posted on 2020-07-08
3753 Statistically correcting dynamical electron scattering improves refinement of protein nanocrystals, including charge refinement of coordinated metals
Thorsten B. Blum; Dominique Housset; Max T.B. Clabbers; Eric van Genderen; Maria Bacia-Verloop; Ulrich Zander; Andrew A. McCarthy; Guy Schoehn; Wai Li Ling; Jan Pieter Abrahams
10.1101/2020.07.08.191049 — biophysics — Posted on 2020-07-08
3754 Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex
James Chen; Brandon Malone; Eliza Llewellyn; Michael Grasso; Patrick M. M. Shelton; Paul Dominic B. Olinares; Kashyap Maruthi; Ed Eng; Hasan Vatandaslar; Brian T. Chait; Tarun Kapoor; Seth A. Darst; Elizabeth A. Campbell
10.1101/2020.07.08.194084 — biophysics — Posted on 2020-07-08
3757 Nano-particles carried by multiple dynein motors: A Self-Regulating Nano-Machine
I. Fayer; G. Halbi; D. Aranovich; S. Gat; S. Bar; V. Erukhimovitch; Rony Granek; Anne Bernheim-Groswasser
10.1101/2020.07.09.194720 — biophysics — Posted on 2020-07-09
3758 Quantification of the effect of site-specific histone acetylation on chromatin transcription rate
Masatoshi Wakamori; Kohki Okabe; Kiyoe Ura; Takashi Funatsu; Masahiro Takinoue; Takashi Umehara
10.1101/679944 — biophysics — Posted on 2020-07-09
3759 Quantification of the effect of site-specific histone acetylation on chromatin transcription rate
Masatoshi Wakamori; Kohki Okabe; Kiyoe Ura; Takashi Funatsu; Masahiro Takinoue; Takashi Umehara
10.1101/679944 — biophysics — Posted on 2020-07-09
3763 Germanium nanospheres for ultraresolution picotensiometry of kinesin motors
Swathi Sudhakar; Mohammad Kazem Abdosamadi; Tobias Jörg Jachowski; Michael Bugiel; Anita Jannasch; Erik Schäffer
10.1101/2020.06.18.159640 — biophysics — Posted on 2020-07-09
3764 Germanium nanospheres for ultraresolution picotensiometry of kinesin motors
Swathi Sudhakar; Mohammad Kazem Abdosamadi; Tobias Jörg Jachowski; Michael Bugiel; Anita Jannasch; Erik Schäffer
10.1101/2020.06.18.159640 — biophysics — Posted on 2020-07-09
3765 Solvent quality and chromosome folding in Escherichia coli
Yingjie Xiang; Ivan V. Surovtsev; Yunjie Chang; Sander K. Govers; Bradley R. Parry; Jun Liu; Christine Jacobs-Wagner
10.1101/2020.07.09.195560 — biophysics — Posted on 2020-07-09
3768 Molecular recognition at septins interfaces: the switches hold the key
Higor Vinícius Dias Rosa; Diego Antonio Leonardo; Gabriel Brognara; José Brandão-Neto; Humberto D’Muniz Pereira; Ana Paula Ulian Araújo; Richard Charles Garratt
10.1101/2020.07.08.161463 — biophysics — Posted on 2020-07-10
3769 Investigation of cell nucleus heterogeneity
Noel Reynolds; Eoin McEvoy; Soham Ghosh; Juan Alberto Panadero Pérez; Corey P. Neu; Patrick McGarry
10.1101/2020.07.08.193854 — biophysics — Posted on 2020-07-10
3770 Role of 1'-Ribose Cyano Substitution for Remdesivir to Effectively Inhibit both Nucleotide Addition and Proofreading in SARS-CoV-2 Viral RNA Replication
Lu Zhang; Dong Zhang; Congmin Yuan; Xiaowei Wang; Yongfang Li; Xilin Jia; Xin Gao; Hui-Ling Yen; Peter Cheung; Xuhui Huang
10.1101/2020.04.27.063859 — biophysics — Posted on 2020-07-10
3771 Role of 1'-Ribose Cyano Substitution for Remdesivir to Effectively Inhibit both Nucleotide Addition and Proofreading in SARS-CoV-2 Viral RNA Replication
Lu Zhang; Dong Zhang; Congmin Yuan; Xiaowei Wang; Yongfang Li; Xilin Jia; Xin Gao; Hui-Ling Yen; Peter Cheung; Xuhui Huang
10.1101/2020.04.27.063859 — biophysics — Posted on 2020-07-10
3776 Optogenetic activation of muscle contraction in vivo
Elahe Ganji; C. Savio Chan; Christopher W. Ward; Megan L. Killian
10.1101/2020.07.07.192377 — bioengineering — Posted on 2020-07-08
3777 Human bone mesoscale 3D structure revisited by plasma focused ion beam serial sectioning
Dakota Marie Binkley; Joseph Deering; Hui Yuan; Aurélien Gourrier; Kathryn Grandfield
10.1101/2020.07.01.180729 — bioengineering — Posted on 2020-07-08
3779 Combined Effect of Shear Stress and Laser-Patterned Topography on Schwann cell Outgrowth: Synergistic or Antagonistic?
Eleftheria Babaliari; Paraskevi Kavatzikidou; Anna Mitraki; Yannis Papaharilaou; Anthi Ranella; Emmanuel Stratakis
10.1101/2020.07.09.195420 — bioengineering — Posted on 2020-07-10
3782 A self-aligning end-effector robot for individual joint training of the human arm
Sivakumar Balasubramanian; Sandeep Guguloth; Javeed Shaikh Mohammed; S Sujatha
10.1101/2020.07.09.195073 — bioengineering — Posted on 2020-07-10
3784 Intermolecular Channels Direct Crystal Orientation in Mineralized Collagen
Yifei Xu; Fabio Nudelman; E. Deniz Eren; Maarten J. M. Wirix; Bram Cantaert; Wouter H. Nijhuis; Daniel Hermida-Merino; Giuseppe Portale; Paul H. H. Bomans; Christian Ottmann; Heiner Friedrich; Wim Bras; Anat Akiva; Joseph Orgel; Fiona C. Meldrum; Nico A. J. M. Sommerdijk
10.1101/2020.07.10.193979 — bioengineering — Posted on 2020-07-10
3788 Proposed allosteric inhibitors bind to the ATP site of CK2α
Paul Brear; Darby Ball; Katherine Stott; Sheena D’Arcy; Marko Hyvönen
10.1101/2020.07.07.191353 — biochemistry — Posted on 2020-07-08
3789 Intramolecular quality control: HIV-1 Envelope gp160 signal-peptide cleavage as a functional folding checkpoint
Nicholas McCaul; Matthias Quandte; Ilja Bontjer; Guus van Zadelhoff; Aafke Land; Rogier W. Sanders; Ineke Braakman
10.1101/2020.07.08.188672 — biochemistry — Posted on 2020-07-08
3790 InteBac - An integrated bacterial and baculovirus expression vector suite
Veronika Altmannova; Andreas Blaha; Susanne Astrinidis; Heidi Reichle; John R. Weir
10.1101/2020.07.09.194696 — biochemistry — Posted on 2020-07-09
3793 Conservation of function with diversification of higher-order structure within sensor histidine kinases
Igor Dikiy; Danielle Swingle; Kaitlyn Toy; Uthama R Edupuganti; Giomar Rivera-Cancel; Kevin H Gardner
10.1101/2020.07.08.194225 — biochemistry — Posted on 2020-07-10
3795 A Topological Switch Enables Misfolding of the Cystic Fibrosis Transmembrane Conductance Regulator
Daniel Scholl; Maud Sigoillot; Marie Overtus; Rafael Colomer Martinez; Chloé Martens; Yiting Wang; Els Pardon; Toon Laeremans; Abel Garcia-Pino; Jan Steyaert; David Noel Sheppard; Jelle Hendrix; Cédric Govaerts
10.1101/2020.07.09.195099 — biochemistry — Posted on 2020-07-10
3796 Kindlin2-mediated phase separation underlies integrin adhesion formation
Yujie Li; Ting Zhang; Huadong Li; Haibing Yang; Ruihong Lin; Kang Sun; Lei Wang; Jing Zhang; Zhiyi Wei; Cong Yu
10.1101/2020.07.10.197400 — biochemistry — Posted on 2020-07-10
3797 Cryo-EM structure of Pol κ-DNA-PCNA holoenzyme and implications for polymerase switching in DNA lesion bypass
Claudia Lancey; Muhammad Tehseen; Masateru Takahashi; Mohamed A Sobhy; Timothy J Ragan; Ramon Crehuet; Samir M Hamdan; Alfredo De Biasio
10.1101/2020.07.10.196956 — biochemistry — Posted on 2020-07-10
3798 Comprehensive in-vivo secondary structure of SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms
Nicholas C Huston; Han Wan; Rafael de Cesaris Araujo Tavares; Craig B Wilen; Anna Marie Pyle
10.1101/2020.07.10.197079 — biochemistry — Posted on 2020-07-10
3799 Bioinformatic and Reactivity-Based Discovery of Linaridins
Matthew A Georgiou; Shravan R Dommaraju; Xiaorui Guo; Douglas A Mitchell
10.1101/2020.07.09.196543 — biochemistry — Posted on 2020-07-10
3800 Activity Mapping the Acyl Carrier Protein - Elongating Ketosynthase Interaction in Fatty Acid Biosynthesis
Jeffrey T Mindrebo; Laetitia Estelle Misson Mindrebo; Caitlin Johnson; Joseph P. Noel; Michael Burkart
10.1101/2020.07.09.196451 — biochemistry — Posted on 2020-07-10
3801 Stabilizing the Closed SARS-CoV-2 Spike Trimer
Jarek Juraszek; Lucy Rutten; Sven Blokland; Pascale Bouchier; Richard Voorzaat; Tina Ritschel; Mark J.G. Bakkers; Ludovic L.R. Renault; Johannes P.M. Langedijk
10.1101/2020.07.10.197814 — biochemistry — Posted on 2020-07-10
3803 Functional and structural characterization of allosteric activation of Phospholipase Cϵ by Rap1A
Monita Sieng; Arielle F. Selvia; Elisabeth E. Garland-Kuntz; Jesse B. Hopkins; Isaac J. Fisher; Andrea T. Marti; Angeline Lyon
10.1101/2020.07.10.191643 — biochemistry — Posted on 2020-07-10
3804 Selective cross-linking of coinciding protein assemblies by in-gel cross-linking mass-spectrometry
Johannes F Hevler; Marie V Lukassen; Alfredo Cabrera-Orefice; Susanne Arnold; Matti F Pronker; Vojtech Franc; Albert J.R. Heck
10.1101/2020.07.10.193003 — biochemistry — Posted on 2020-07-10
3811 Consistency of social interactions in sooty mangabeys and chimpanzees
Alexander Mielke; Anna Preis; Liran Samuni; Jan Frederik Gogarten; Jack Lester; Catherine Crockford; Roman Martin Wittig
10.1101/2020.07.10.196949 — animal behavior and cognition — Posted on 2020-07-10
3812 Genetic variation in anesthesia success in a New Zealand freshwater snail
Qiudong Song; Richard Magnuson; Marissa Roseman; Joseph Jalinsky; Maurine Neiman
10.1101/2020.07.09.194050 — animal behavior and cognition — Posted on 2020-07-10
3815 Tau forms oligomeric complexes on microtubules that are distinct from pathological oligomers in disease
Gyparaki, M. T.; Arab, A.; Sorokina, E. M.; Santiago-Ruiz, A. N.; Bohrer, C. H.; Xiao, J.; Lakadamyali, M.
10.1101/2020.07.07.192146 — cell biology — Posted on 2020-07-08
3816 Optoribogenetic control of regulatory RNA molecules
Pilsl, S.; Morgan, C.; Choukeife, M.; Moeglich, A.; Mayer, G.
10.1101/2020.07.07.191379 — molecular biology — Posted on 2020-07-08
3819 Modulation of neural oscillations during working memory update, maintenance, and readout: an hdEEG study
Semprini, M.; Bonassi, G.; Barban, F.; Pelosin, E.; Iandolo, R.; Chiappalone, M.; Mantini, D.; Avanzino, L.
10.1101/2020.07.07.191619 — neuroscience — Posted on 2020-07-07
3821 Listeners with congenital amusia are sensitive to context uncertainty in melodic sequences
Quiroga-Martinez, D. R.; Tillmann, B.; Brattico, E.; Cholvy, F.; Fornoni, L.; Vuust, P.; Caclin, A.
10.1101/2020.07.07.191031 — neuroscience — Posted on 2020-07-07
3824 Effects of temperature on Zika dynamics and control
Ngonghala, C. N.; Ryan, S. J.; Tesla, B.; Demokovsky, L. R.; Mordecai, E. A.; Murdock, C. C.; Bonds, M. H.
10.1101/855072 — ecology — Posted on 2020-07-07
3825 Trophic cascade driven by behavioural fine-tuning as naive prey rapidly adjust to a novel predator
Jolly, C. J.; Smart, A. S.; Moreen, J.; Webb, J. K.; Gillespie, G. R.; Phillips, B. L.
10.1101/856997 — ecology — Posted on 2020-07-07
3826 Mechanism and effects of the skeletal muscle Nav1.4 inhibition by cannabidiol
Ghovanloo, M.-R.; Choudhury, K.; Bandaru, T. S.; Fouda, M. A.; Rayani, K.; Rusinova, R.; Phaterpekar, T.; Nelkenbrecher, K.; Watkins, A. R.; Poburko, D.; Thewalt, J.; Andersen, O. S.; Delemotte, L.; Goodchild, S. J.; Ruben, P.
10.1101/2020.06.30.180943 — biophysics — Posted on 2020-07-07
3827 The genetic architecture of structural left-right asymmetry of the human brain
Sha, Z.; Schijven, D.; Carrion-Castillo, A.; Joliot, M.; Mazoyer, B.; Fisher, S.; Crivello, F.; Francks, C.
10.1101/2020.06.30.179721 — neuroscience — Posted on 2020-07-07
3828 DNA from dried blood spots yields high quality sequences for exome analysis
Sunderam, U.; Adhikari, A. N.; Kundu, K.; Puck, J. M.; Currier, R.; Kwok, P.-Y.; Brenner, S. E.; Srinivasan, R.
10.1101/2020.05.19.105304 — genomics — Posted on 2020-07-07
3829 Empirical dynamic modeling reveals ecological drivers of dengue dynamics
Nova, N.; Deyle, E. R.; Shocket, M.; MacDonald, A. J.; Childs, M.; Rypdal, M.; Sugihara, G.; Mordecai, E. A.
10.1101/2019.12.20.883363 — ecology — Posted on 2020-07-07
3832 ATP-Citrate lyase fuels axonal transport across species
Nguyen, L.; Even, A.; Morelli, G.; Le Bail, R.; Shilian, M.; Turchetto, S.; Broix, L.; Brandis, A.; Inbar, S.; Chariot, A.; Saudou, F.; Dietrich, P.; Dragatsis, I.; Brone, B.; Rigo, J.-M.; Weil, M.
10.1101/2020.07.07.192096 — cell biology — Posted on 2020-07-07
3839 Effect of acute physical exercise on motor sequence memory
Marin Bosch, B.; Bringard, A.; Logrieco, M. G.; Imobersteg, N.; Lauer, E.; Thomas, A.; Ferretti, G.; Schwartz, S.; Igloi, K.
10.1101/2020.01.28.922930 — neuroscience — Posted on 2020-07-07
3840 Effects of Weather and Season on Human Brain Volume
Book, G. A.; Meda, S. A.; Janssen, R.; Dager, A. D.; Poppe, A.; Stevens, M. C.; Assaf, M.; Glahn, D.; Pearlson, G. D.
10.1101/2020.07.07.191239 — neuroscience — Posted on 2020-07-07
3841 Simultaneous human intracerebral stimulation and HD-EEG: ground-truth for source localization methods
Mikulan, E.; Russo, S.; Parmigiani, S.; Sarasso, S.; Zauli, F. M.; Rubino, A.; Avanzini, P.; Cattani, A.; Sorrentino, A.; Gibbs, S.; Cardinale, F.; Sartori, I.; Nobili, L.; Massimini, M.; Pigorini, A.
10.1101/2020.02.14.948984 — neuroscience — Posted on 2020-07-07
3842 Ultra-accurate Microbial Amplicon Sequencing with Synthetic Long Reads
Callahan, B. J.; Grinevich, D.; Thakur, S.; Balamotis, M. A.; Yehezkel, T. B.
10.1101/2020.07.07.192286 — microbiology — Posted on 2020-07-07
3843 Multiple blood feeding in mosquitoes shortens the Plasmodium falciparum incubation period and increases malaria transmission potential
Shaw, W. R.; Holmdahl, I. E.; Itoe, M. A.; Werling, K.; Marquette, M.; Paton, D. G.; Singh, N.; Buckee, C. O.; Childs, L. M.; Catteruccia, F.
10.1101/2020.03.24.991356 — microbiology — Posted on 2020-07-07
3845 Tailored intestinal IgA responses can set an evolutionary trap for Salmonella Typhimurium
Diard, M.; Bakkeren, E.; Hoces, D.; Lentsch, V.; Arnoldini, M.; Boehi, F.; Schumann-Moor, K.; Adamcik, J.; Piccoli, L.; Lanzavecchia, A.; Stadtmueller, B.; Donohue, N.; Vanderwoude, M.; Viollier, P.; Falquet, L.; Hockenberry, A.; Wuethrich, D.; Bonfiglio, F.; Loverdo, C.; Egli, A.; Zandomeneghi, G.; Mezzenga, R.; Holst, O.; Meier, B.; Hardt, W.-D.; Slack, E.
10.1101/824821 — immunology — Posted on 2020-07-07
3847 The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types
Daniloski, Z.; Jordan, T. X.; Ilmain, J.; Guo, X.; Bhabha, G.; tenOever, B.; Sanjana, N. E.
10.1101/2020.06.14.151357 — genetics — Posted on 2020-07-07
3856 Boosting innate immunity: Asaia bacteria expressing a protein from Wolbachia determine macrophage activation and killing of Leishmania
VAROTTO-BOCCAZZI, I.; EPIS, S.; ARNOLDI, I.; CORBETT, Y.; GABRIELI, P.; PARONI, M.; NODARI, R.; BASILICO, N.; SACCHI, L.; GRAMICCIA, M.; GRADONI, L.; TRANQUILLO, V.; Bandi, C.
10.1101/2020.06.22.164145 — microbiology — Posted on 2020-07-07
3859 Multilevel community assembly of the tadpole gut microbiome
Correa, D. T.; Rodriguez, D.; Emer, C.; Saenz, D.; Adams, C. K.; Schiesari, L. C.; Matz, M. V.; Leibold, M. A.
10.1101/2020.07.05.188698 — ecology — Posted on 2020-07-07
3860 Immobilised collagen prevents shedding and induces sustained GPVI clustering and signalling in platelets.
Pallini, C.; Pike, J. A.; O'Shea, C.; Andrews, R. K.; Gardiner, E. E.; Watson, S. P.; Poulter, N. S.
10.1101/2020.07.07.192435 — cell biology — Posted on 2020-07-07
3861 Phosphoregulation of HORMA domain protein HIM-3 promotes asymmetric synaptonemal complex disassembly in meiotic prophase in C. elegans
Sato-Carlton, A.; Nakamura-Tabuchi, C.; Li, X.; Boog, H.; Lehmer, M. K.; Rosenberg, S. C.; Barroso, C.; Martinez-Perez, E.; Corbett, K. D.; Carlton, P. M.
10.1101/2020.07.01.182063 — cell biology — Posted on 2020-07-07
3862 Protein Crowding Mediates Membrane Remodeling in Upstream ESCRT-induced Formation of Intraluminal Vesicles
Liese, S.; Wenzel, E. M.; Kjos, I.; Rojas Molina, R. V.; Schultz, S. W.; Brech, A.; Stenmark, H.; Raiborg, C.; Carlson, A.
10.1101/834457 — biophysics — Posted on 2020-07-07
3866 Zinc finger protein SALL4 functions through an AT-rich motif to regulate gene expression
Kong, N. R.; Bassal, M. A.; Tan, H. K.; Kurland, J. V.; Yong, K. J.; Young, J. J.; Yang, Y.; Li, F.; Lee, J.; Liu, Y.; Wu, C. S.; Stein, A.; Luo, H.; Silberstein, L.; Bulyk, M. L.; Tenen, D. G.; Chai, L.
10.1101/2020.07.03.186783 — molecular biology — Posted on 2020-07-07
3867 Decoding ribosomal RNA modification dynamics at single molecule resolution
Begik, O.; Lucas, M. C.; Ramirez, J. M.; Milenkovic, I.; Cruciani, S.; Vieira, H. G. S.; Medina, R.; Liu, H.; Sas-Chen, A.; Mattick, J. S.; Schwartz, S.; Novoa, E. M.
10.1101/2020.07.06.189969 — molecular biology — Posted on 2020-07-07
3868 Genome-wide analysis in Escherichia coli unravels an unprecedented level of genetic homoplasy associated with cefotaxime resistance.
Coolen, J. P. M.; den Drijver, E.; Verweij, J. J.; Schildkraut, J.; Neveling, K.; Melchers, W. J. G.; Kolwijck, E.; Wertheim, H. F. L.; Kluytmans, J.; Huynen, M. A.
10.1101/2020.06.01.128843 — microbiology — Posted on 2020-07-07
3869 HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-kB/IRF3 nuclear transport
Khan, H.; Sumner, R. P.; Rasaiyaah, J.; Tan, C. P.; Rodriguez-Plata, M. T.; Van Tulleken, C.; Fink, D.; Zuliani-Alvarez, L.; Thorne, L.; Stirling, D.; Milne, R. S. B.; Towers, G. J.
10.1101/2020.02.22.960757 — microbiology — Posted on 2020-07-07
3870 Publicly available hiPSC lines with extreme polygenic risk scores for modeling schizophrenia
Rehbach, K.; Zhang, H.; Das, D.; Abdollahi, S.; Prorok, T.; Ghosh, S.; Weintraub, S.; Genovese, G.; Powell, S.; Lund, A.; Akbarian, S.; Eggan, K.; McCarroll, S. A.; Duan, J.; Avramopoulos, D.; Brennand, K. J.
10.1101/2020.07.04.185348 — genomics — Posted on 2020-07-07
3873 Trophic cascade driven by behavioural fine-tuning as naive prey rapidly adjust to a novel predator
Jolly, C. J.; Smart, A. S.; Moreen, J.; Webb, J. K.; Gillespie, G. R.; Phillips, B. L.
10.1101/856997 — ecology — Posted on 2020-07-07
3876 Analysis of the transcriptome and DNA methylome in response to acute and recurrent low glucose in human primary astrocytes
Weightman Potter, P. G.; Washer, S.; Jeffries, A. R.; Holley, J. E.; Gutowski, N. J.; Dempster, E. L.; Beall, C.
10.1101/2020.07.07.191262 — neuroscience — Posted on 2020-07-07
3877 Privatization of biofilm matrix in structurally heterogeneous biofilms
Otto, S. B.; Martin, M.; Schafer, D.; Hartmann, R.; Drescher, K.; Brix, S.; Dragos, A.; Kovacs, A. T.
10.1101/742593 — microbiology — Posted on 2020-07-07
3878 Enhancer priming by H3K4 methylation safeguards germline competence
Bleckwehl, T.; Schaaf, K.; Crispatzu, G.; Respuela, P.; Bartusel, M.; Benson, L.; Clark, S. J.; Dorighi, K. M.; Barral, A.; Laugsch, M.; Manzanares, M.; Wysocka, J.; Reik, W.; Rada-Iglesias, A.
10.1101/2020.07.07.192427 — genomics — Posted on 2020-07-07
3879 Human Whole Genome Sequencing in South Africa
Glanzmann, B.; Jooste, T.; Ghoor, S.; Gordon, R.; Mia, R.; Mao, J.; Li, H.; Charls, P.; Douman, C.; Kotze, M.; Peeters, A.; Loots, G.; Esser, M.; Tiemessen, C.; Wilkinson, R.; Louw, J.; Gray, G.; Warren, R.; Moller, M.; Kinnear, C.
10.1101/2020.06.10.144402 — genomics — Posted on 2020-07-07
3880 Leveraging eQTLs to identify individual-level tissue of interest for a complex trait
Majumdar, A.; Giambartolomei, C.; Cai, N.; Kumar Freund, M.; Haldar, T.; Schwarz, T.; Flint, J.; Pasaniuc, B.
10.1101/674226 — genetics — Posted on 2020-07-07
3884 Neurotrophic Factor-Laden Acellular Chondroitin Sulfate Scaffolds Promote Chronic Functional Recovery After Severe Traumatic Brain Injury
Latchoumane, C.-F. V.; Betancur, M. I.; Simchick, G. A.; Sun, M. K.; Forghani, R.; Lenear, C. E.; Ahmed, A.; Mohankumar, R.; Balaji, N.; Mason, H. D.; Holmes, P. V.; Zhao, Q.; Bellamkonda, R. V.; Karumbaiah, L.
10.1101/2020.06.21.116970 — bioengineering — Posted on 2020-07-07
3885 Reversible auto-inhibitory regulation of Escherichia coli metallopeptidase BepA for selective β-barrel protein degradation
Daimon, Y.; Narita, S.-i.; Miyazaki, R.; Hizukuri, Y.; Mori, H.; Tanaka, Y.; Tsukazaki, T.; Akiyama, Y.
10.1101/2020.07.07.192476 — biochemistry — Posted on 2020-07-07
3887 Improved control of Septoria tritici blotch in durum wheat using cultivar mixtures
Ben M'Barek, S.; Karisto, P.; Abdedayem, W.; Laribi, M.; Fakhfakh, M.; Kouki, H.; Mikaberidze, A.; Yahyaoui, A.
10.1101/664078 — plant biology — Posted on 2020-07-07
3888 Extra-hematopoietic immunomodulatory role of the SCID-susceptibility gene DOCK-2 identified by stepwise maturation of human iPSCs into clonogenic mesodermal stromal progenitors
Scharler, C.; Poupardin, R.; Peking, P.; Wolf, M.; Brachtl, G.; Daheron, L.; Schallmoser, K.; Juerchott, K.; Stachelscheid, H.; Volk, H.-D.; STRUNK, D.
10.1101/2020.07.07.192385 — immunology — Posted on 2020-07-07
3891 Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during development
Espinola, S.; Goetz, M.; Fiche, J.-B.; Bellec, M.; Houbron, C.; Cardozo Gizzi, A. M.; Lagha, M.; Nollmann, M.
10.1101/2020.07.07.191015 — genomics — Posted on 2020-07-07
3892 A generic white pupae sex selection phenotype for insect pest control
Ward, C. M.; Aumann, R. A.; Whitehead, M. A.; Nikolouli, K.; Leveque, G.; Gouvi, G.; Fung, E.; Reiling, S. J.; Djambazian, H. H. V.; Hughes, M. A.; Whiteford, S.; Caceres-Barrios, C.; Nguyen, N. M. T.; Choo, A.; Crisp, P.; Sim, S.; Geib, S.; Marec, F.; Haecker, I.; Ragoussis, J.; Darby, A. C.; Bourtzis, K.; Baxter, S. W.; Schetelig, M. F.
10.1101/2020.05.08.076158 — genetics — Posted on 2020-07-07
3894 Notch controls arterialization by regulating the cell cycle and not differentiation
Luo, W.; Garcia-Gonzalez, I.; Fernandez-Chacon, M.; Casquero-Garcia, V.; Benedito, R.
10.1101/2020.07.07.192344 — developmental biology — Posted on 2020-07-07
3895 LOSS OF UBIQUITIN LIGASE STUB1 AMPLIFIES IFNγ-R1/JAK1 SIGNALING AND SENSITIZES TUMORS TO IFNγ
Apriamashvili, G.; Vredevoogd, D. W.; Krijgsman, O.; Bleijerveld, O. B.; Ligtenberg, M. A.; de Bruijn, B.; Boshuizen, J.; D'Empaire Altimari, D.; Visser, N. L.; Londino, J. D.; Altelaar, M.; Peeper, D. S.
10.1101/2020.07.07.191650 — cancer biology — Posted on 2020-07-07
3896 Accurate Fetal Variant Calling in the Presence of Maternal Cell Contamination
Nabieva, E.; Mishra Sharma, S.; Kapushev, Y.; Garushyans, S. K.; Fedotova, A. V.; Moskalenko, V. N.; Serebrenikova, T.; Glazyrina, E.; Kanivets, I. V.; Pyankov, D. V.; Neretina, T. V.; Logacheva, M. D.; Bazykin, G. A.; Yarotsky, D.
10.1101/552414 — bioinformatics — Posted on 2020-07-07
3897 Single species RNA purification with DNA nanoswitches
Zhou, L.; Cavaliere, C.; Hayden, A.; Dey, P.; Mao, S.; Chandrasekaran, A. R.; Sheng, J.; Dey, B. K.; Halvorsen, K.
10.1101/2020.07.07.191338 — molecular biology — Posted on 2020-07-07
3898 A Trypanosoma cruzi Zinc Finger protein that controls expression of epimastigote specific genes and affects metacyclogenesis
Tavares, T. S.; Muegge, F. L. B.; Grazielle-Silva, V.; Valente, B. M.; Goes, W. M.; Oliveira, A. E. R.; Belew, A. T.; Guarneri, A. A.; Pais, F. S. M.; El-Sayed, N. M.; Teixeira, S. M. R.
10.1101/2020.07.07.189688 — molecular biology — Posted on 2020-07-07
3899 A pVII positioning code determines the dynamics of Adenoviral nucleoprotein structure and primes it for early gene activation
Schwartz, U.; Komatsu, T.; Huber, C.; Lagadec, F.; Silberhorn, E.; Bertrand, E.; Wodrich, H.; Laengst, G.
10.1101/2020.07.07.190926 — microbiology — Posted on 2020-07-07
3900 The impact of plasma membrane lipid composition on flagella-mediated adhesion of enterohemorrhagic Escherichia coli
Cazzola, H.; Lemaire, L.; Acket, S.; Prost, E.; Duma, L.; Erhardt, M.; Cechova, P.; Trouillas, P.; Mohareb, F. R.; Rossi, C.; Rossez, Y.
10.1101/2020.07.07.189852 — microbiology — Posted on 2020-07-07
3901 Cycling in degradation of organic polymers and uptake of nutrients by a litter-degrading fungus
Vos, A. M.; Bleichrodt, R.-J.; Herman, K. C.; Ohm, R. A.; Scholtmeijer, K.; Schmitt, H.; Lugones, L. G.; Wosten, H. A.
10.1101/2020.07.07.170282 — microbiology — Posted on 2020-07-07
3903 Genome-wide assessment of REST binding profiles reveals distinctions between human and mouse hippocampus
McGann, J. C.; Spinner, M. A.; Garg, S. K.; Mullendorf, K.; Woltjer, R. L.; Mandel, G.
10.1101/2020.07.07.192229 — genomics — Posted on 2020-07-07
3905 Decorin, a novel negative modulator of E-cadherin in inflammatory breast cancer
Hu, X.; Schlee Villodre, E.; Larson, R. A.; Rahal, O. M.; Wang, X.; Gong, Y.; Song, J.; Krishnamurthy, S.; Ueno, N. T.; Tripathy, D.; Woodward, W. A.; Debeb, B. G.
10.1101/2020.07.07.190496 — cancer biology — Posted on 2020-07-07
3907 Structural and molecular dynamics of Mycobacterium tuberculosis malic enzyme, a potential anti-TB drug target
Burley, K. H.; Cuthbert, B. J.; Basu, P.; Newcombe, J.; Irimpan, E. M.; Quechol, R.; Foik, I. P.; Mobley, D. L.; Beste, D. J.; Goulding, C. W.
10.1101/2020.07.07.192161 — biochemistry — Posted on 2020-07-07
3908 Metabolic fate of human immunoactive sterols in Mycobacterium tuberculosis
Varaksa, T.; Bukhdruker, S.; Grabovec, I.; Marin, E.; Kavaleuski, A.; Gusach, A.; Kovalev, K.; Maslov, I.; Luginina, A.; Zabelskiy, D.; Astashkin, R.; Shevtsov, M.; Smolskaya, S.; Kavaleuskaya, A.; Shabunya, P.; Baranovsky, A.; Dolgopalets, V.; Charnou, Y.; Savachka, A.; Litvinovskaya, R.; Hurski, A.; Shevchenko, E.; Rogachev, A.; Mishin, A.; Gordeliy, V.; Gabrielian, A.; Hurt, D.; Nikonenko, B.; Majorov, K.; Apt, A.; Rosenthal, A.; Gilep, A.; Borshchevskiy, V.; Strushkevich, N.
10.1101/2020.07.07.192294 — biochemistry — Posted on 2020-07-07
3911 A rapidly adaptable biomaterial vaccine for SARS-CoV-2
Langellotto, F.; Seiler, B. T.; Yu, J.; Cartwright, M. J.; White, D.; Yeager, C.; Super, M.; Doherty, E. J.; Barouch, D. H.; Mooney, D. J.
10.1101/2020.07.07.192203 — immunology — Posted on 2020-07-07
3913 The evolutionary history of ACE2 usage within the coronavirus subgenus Sarbecovirus
Wells, H. L.; Letko, M. C.; Lasso, G.; Ssebide, B.; Nziza, J.; Byarugaba, D. K.; Navarrete-Macias, I.; Liang, E.; Cranfield, M.; Han, B. A.; Tingley, M. W.; Diuk-Wasser, M.; Goldstein, T.; Kreuder Johnson, C.; Mazet, J.; Chandran, K.; Munster, V.; Gilardi, K.; Anthony, S. J.
10.1101/2020.07.07.190546 — evolutionary biology — Posted on 2020-07-07
3914 A Fluorescence-based High Throughput-Screening assay for the SARS-CoV RNA synthesis complex
Eydoux, C.; Fattorini, V.; Shannon, A.; Le, T.-T.-N.; Didier, B.; Canard, B.; Guillemot, J.-C.
10.1101/2020.07.07.192005 — biochemistry — Posted on 2020-07-07
3917 How old are dragonflies and damselflies? Odonata (Insecta) transcriptomics resolve familial relationships
Kohli, M.; Letsch, H.; Greve, C.; Bethoux, O.; Deregnacourt, I.; Liu, S.; Zhou, X.; Donath, A.; Mayer, C.; Podsiadlowski, L.; Machida, R.; Niehuis, O.; Rust, J.; Wappler, T.; Yu, X.; Misof, B.; Ware, J.
10.1101/2020.07.07.191718 — evolutionary biology — Posted on 2020-07-07
3919 Changes in insulin resistance do not occur in parallel with changes in mitochondrial content and function in male rats
Genders, A. J.; Kuang, J.; Marin, E. C.; Saner, N. J.; Botella, J.; Jacques, M.; McConell, G. K.; Andrade-Souza, V. A.; Chagolla, J.; Bishop, D. J.
10.1101/2020.07.06.190702 — physiology — Posted on 2020-07-07
3921 Occipital Intralobar fasciculi and a novel description of three forgotten tracts
Bugain, M.; Dimech, Y.; Torzhenskaya, N.; Thiebaut de Schotten, M.; Caspers, S.; Muscat, R.; Bajada, C. J.
10.1101/2020.07.07.191767 — neuroscience — Posted on 2020-07-07
3922 Cricket genomes: the genomes of future food
Ylla, G.; Nakamura, T.; Itoh, T.; Kajitani, R.; Toyoda, A.; Tomonari, S.; Bando, T.; Ishimaru, Y.; Watanabe, T.; Fuketa, M.; Matsuoka, Y.; Noji, S.; Mito, T.; Extavour, C. G.
10.1101/2020.07.07.191841 — genomics — Posted on 2020-07-07
3930 Anoxygenic phototrophic Chloroflexota member uses a Type I reaction center
Tsuji, J. M.; Shaw, N. A.; Nagashima, S.; Venkiteswaran, J. J.; Schiff, S. L.; Hanada, S.; Tank, M.; Neufeld, J. D.
10.1101/2020.07.07.190934 — microbiology — Posted on 2020-07-07
3935 The Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy
Corkery, D.; Nadeem, A.; Aung, K. M.; Hassan, A.; Liu, T.; Cervantes-Rivera, R.; Lystad, A. H.; Wang, H.; Persson, K.; Puhar, A.; Simonsen, A.; Uhlin, B. E.; Wai, S. N.; Wu, Y.
10.1101/2020.07.07.191411 — cell biology — Posted on 2020-07-07
3936 A fluorescent L-2-hydroxyglutarate biosensor
Kang, Z.; Zhang, M.; Gao, K.; Zhang, W.; Liu, Y.; Xiao, D.; Guo, S.; Ma, C.; Gao, C.; Xu, P.
10.1101/2020.07.07.187567 — biochemistry — Posted on 2020-07-07
3937 Nonsense-mediated mRNA decay relies on "two-factor authentication" by SMG5-SMG7
Boehm, V.; Kueckelmann, S.; Gerbracht, J. V.; Britto-Borges, T.; Altmueller, J.; Dieterich, C.; Gehring, N. H.
10.1101/2020.07.07.191437 — molecular biology — Posted on 2020-07-07
3938 Enterococcal PrgU mitigates PrgB overexpression toxicity by binding to intergenic RNA downstream of the PQ promoter
Lassinantti, L.; Camacho, M. I.; Erickson, R. J. B.; Willett, J.; De Lay, N. R.; ter Beek, J.; Dunny, G. M.; Christie, P. J.; Berntsson, R. P.-A.
10.1101/2020.07.06.190884 — molecular biology — Posted on 2020-07-07
3940 RNF219 interacts with CCR4-NOT in regulating stem cell differentiation
Du, H.; Chen, C.; Wang, Y.; Yang, Y.; Che, Z.; Liu, X.; Meng, S.; Guo, C.; Xu, M.; Fang, H.; Lin, C.; Luo, Z.
10.1101/2020.07.06.190728 — molecular biology — Posted on 2020-07-07
3946 AXL is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
Du, W.; Huang, H.; Wang, Z.; Toombs, J. E.; Phinney, N. Z.; Zhang, Y.; Beg, M. S.; Wilkie, T. M.; Lorens, J.; Brekken, R. A.
10.1101/2020.07.06.190363 — cancer biology — Posted on 2020-07-07
3949 Repurposed Drugs Block Toxin-Driven Platelet Clearance by the Hepatic Ashwell-Morell Receptor to Clear Staphylococcus aureus Bacteremia
Sun, J.; Uchiyama, S.; Olson, J.; Morodomi, Y.; Cornax, I.; Ando, N.; Kohno, Y.; Kyaw, M. M. T.; Aguilar, B.; Haste, N. M.; Kanaji, S.; Kanaji, T.; Rose, W. E.; Sakoulas, G.; Marth, J. D.; Nizet, V.
10.1101/2020.07.06.190322 — microbiology — Posted on 2020-07-07
3950 NMD is required for timely cell fate transitions by fine-tuning gene expression and controlling translation
Galimberti, E.; Sehlke, R.; Huth, M.; Garmhausen, M.; Romeike, M.; Ramesmayer, J.; Stummer, S.; Titz-Teixeira, F.; Herzog, V.; Chugunova, A.; Leesch, K. F.; Holcik, L.; Santini, L.; Lackner, A.; von Haeseler, A.; Buecker, C.; Pauli, A.; Schoefer, C.; Ameres, S. L.; Smith, A.; Beyer, A.; Leeb, M.
10.1101/2020.07.07.180133 — cell biology — Posted on 2020-07-07
3951 SimText: A text mining framework for interactive analysis and visualization of similarities among biomedical entities
Gramm, M.; Perez-Palma, E.; Schumacher-Bass, S. M.; Dalton, J. E.; Leu, C.; Blankenberg, D.; Lal, D.
10.1101/2020.07.06.190629 — bioinformatics — Posted on 2020-07-07
3952 Dimeric prion protein ligand activates Adgrg6 but does not rescue myelinopathy of PrP-deficient mice
Henzi, A.; Senatore, A.; Lakkaraju, A.; Scheckel, C.; Mühle, J.; Reimann, R.; Sorce, S.; Schertler, G. F. X.; Toyka, K. V.; Aguzzi, A.
10.1101/2020.07.07.191452 — neuroscience — Posted on 2020-07-07
3953 Translating insights from the seed metabolome into improved prediction for healthful compounds in oat
Campbell, M. T.; Hu, H.; Yeats, T.; Caffe-Treml, M.; Gutierrez, L.; Smith, K.; Sorrells, M. E.; Gore, M. A.; Jannink, J.-L.
10.1101/2020.07.06.190512 — genomics — Posted on 2020-07-07
3955 KDS2010, a newly developed reversible MAO-B inhibitor, as an effective therapeutic candidate for Parkinson's disease
Nam, M.-H.; Park, J.-H.; Song, H. J.; Choi, J. W.; Kim, S.; Jang, B. K.; Yoon, H. H.; Heo, J. Y.; Cho, D.-W.; Yang, Y.-S.; Han, S.-C.; Kim, S.; Oh, S.-J.; Jeon, S. R.; Park, K. D.; Lee, C. J.
10.1101/2020.07.06.190579 — pharmacology and toxicology — Posted on 2020-07-07
3956 A two-step approach to testing overall effect of gene-environment interaction for multiple phenotypes
Majumdar, A.; Burch, K.; Sankararaman, S.; Pasaniuc, B.; Gauderman, W. J.; Witte, J. S.
10.1101/2020.07.06.190256 — genetics — Posted on 2020-07-07
3960 Neural effects of propofol-induced unconsciousness and its reversal using thalamic stimulation
Bastos, A. M.; Donoghue, J. A.; Brincat, S. L.; Mahnke, M.; Yanar, J.; Correa, J.; Waite, A. S.; Lundqvist, M.; Roy, J.; Brown, E. N.; Miller, E. K.
10.1101/2020.07.07.190132 — neuroscience — Posted on 2020-07-07
3963 The Connexin 43 Carboxyl Terminal Mimetic Peptide alphaCT1 Prompts Differentiation of a Collagen Scar Matrix Resembling Unwounded Skin
Montgomery, J.; Richardson, W. J.; Rhett, J. M.; Bustos, F.; Degen, K.; Ghatnekar, G.; Grek, C. L.; Marsh, S.; Jourdan, L. J.; Holmes, J. W.; Gourdie, R. G.
10.1101/2020.07.07.191742 — cell biology — Posted on 2020-07-07
3964 MATHEMATICAL MODELING OF RETINAL DEGENERATION: AEROBIC GLYCOLYSIS IN A SINGLE CONE
Camacho, E.; Dobrovera, A.; Larripa, K.; Radulescu, A.; Schmidt, D.; Trejo, I.
10.1101/2020.07.06.190470 — systems biology — Posted on 2020-07-07
3966 Favipiravir and severe acute respiratory syndrome coronavirus 2 in hamster model
Driouich, J.-S.; Cochin, M.; Lingas, G.; Moureau, G.; Touret, F.; Petit, P.-R.; Piorkowski, G.; Barthelemy, K.; Coutard, B.; Guedj, J.; de Lamballerie, X.; Solas, C.; Nougairede, A.
10.1101/2020.07.07.191775 — microbiology — Posted on 2020-07-07
3969 SARS-CoV-2 Nsp1 binds ribosomal mRNA channel to inhibit translation
Schubert, K.; Karousis, E. D.; Jomaa, A.; Scaiola, A.; Echeverria, B.; Gurzeler, L.-A.; Leibundgut, M.; Thiel, V.; Muehlemann, O.; Ban, N.
10.1101/2020.07.07.191676 — molecular biology — Posted on 2020-07-07
3981 Visual mate preference evolution during butterfly speciation is linked to neural processing genes
Rossi, M.; Hausmann, A. E.; Thurman, T. J.; Montgomery, S. H.; Papa, R.; Jiggins, C. D.; Mcmillan, W. O.; Merrill, R. M.
10.1101/2020.03.22.002121 — evolutionary biology — Posted on 2020-07-07
3982 Strategic stakeholders typology and mapping using stakeholder network analyses on integrated crops-livestock farming systems in West New Guinea
Iyai, D. A.; Widayati, I. W.; Fatem, H. F.; Nurhayati, D. D.; Arim, M. M.; Monim, H. H.; Ronsumbre, A. A.; Baaka, A.; Orisu, M. L.; Saragih, D. T. R.; Syufi, Y.; Nuhuyanan, L. E.; Woran, D.; Mofu, W. Y.; Randa, S. Y.; Sonbait, L. Y.; Arizona, R.; Baransano, M.; Seseray, D. Y.; Pattiselanno, F.; Yaku, A.; Koibur, J. F.
10.1101/2020.07.06.189217 — zoology — Posted on 2020-07-06
3985 Sodium Diethyldithiocarbamate antiparasitic activity against different Trypanosoma cruzi strains: Insights of its biological activity
Oliveira, J.; Torres, T. M.; Moreno, C.; Amorim-Carmo, B.; Damasceno, I.; Soares, A. K.; Barbosa, J. d. S.; Rocha, H. A.; Silva, M. S.
10.1101/2020.07.06.189233 — pharmacology and toxicology — Posted on 2020-07-06
3988 Astrocytes express DMT1 and transferrin receptors, which transport iron thus activating Ca2+ signalling: possible role in neuroprotection against iron overload?
Xia, M.; Guan, W.; Ji, M.; Li, S.; Li, Z.; Chen, B.; Zhang, M.; Liang, S.; Gong, W.; Dong, C.; Chen, B.; Wen, G.; Zhan, X.; Zhang, D.; Li, X.; Verkhratsky, A.; Li, B.
10.1101/2020.07.06.190652 — molecular biology — Posted on 2020-07-06
3995 Genome-wide analysis clarifies the population genetic structure of wild Gilthead Sea Bream (Sparus aurata)
Maroso, F.; Gkagkavouzis, K.; De Innocentiis, S.; Hillen, J.; do Prado, F.; Karaiskou, N.; Taggart, J. B.; Carr, A.; Nielsen, E.; Triantafyllidis, A.; Bargelloni, L.; Aquatrace consortium,
10.1101/2020.07.06.189241 — ecology — Posted on 2020-07-06
3998 Stress-induced epigenetic regulation of transcription in neocortical excitatory neurons drives depression-like behavior
Kwon, D. Y.; Hu, P.; Zhao, Y.; Beagan, J. A.; Nofziger, J. H.; Cui, Y.; Xu, B.; Zaitseva, D.; Phillips-Cremins, J. E.; Blendy, J. A.; Wu, H.; Zhou, Z.
10.1101/2020.07.06.190280 — neuroscience — Posted on 2020-07-06
4006 Wide-Field Calcium Imaging of Dynamic Cortical Networks During Locomotion
West, S. L.; Aronson, J.; Popa, L. S.; Carter, R. E.; Shekhar, A.; Feller, K. D.; Ghanbari, L.; Kodandaramaiah, S. B.; Ebner, T. J.
10.1101/2020.07.06.189670 — neuroscience — Posted on 2020-07-06
4009 Decoding ribosomal RNA modification dynamics at single molecule resolution
Begik, O.; Lucas, M. C.; Ramirez, J. M.; Cruciani, S.; Novoa, E. M.; Cruciani, S.; Vieira, H. G. S.; Medina, R.; Liu, H.; Sas-Chen, A.; Mattick, J. S.; Schwartz, S.
10.1101/2020.07.06.189969 — molecular biology — Posted on 2020-07-06
4010 Dynamics of Prion Proliferation Under CombinedTreatment of Pharmacological Chaperones andInterferons via a Mathematical Model
Ghosh, A.; N. Garzon, D.; Castillo, Y.; Navas-Zuloaga, M.; Culik, N.; Darwin, L.; Hardin, A.; Yang, A.; Garsow, C. C.; Rios-Soto, K.
10.1101/2020.07.06.190637 — cell biology — Posted on 2020-07-06
4011 A DNA-based optical nanosensor for in vivo imaging of acetylcholine in the peripheral nervous system
Xia, J.; Yang, H.; Mu, M.; Micovic, N.; Poskanzer, K. E.; Monaghan, J. R.; Clark, H. A.
10.1101/2020.07.06.189696 — bioengineering — Posted on 2020-07-06
4012 Robust frequency-encoded dynamics in a minimal synthetic phytohormone crosstalk
Perez Garcia, S.; Garcia Navarrete, M.; Ruiz Sanchis, D.; Prieto Navarro, C.; Avdovic, M.; Pucciariello, O.; Wabnik, K.
10.1101/2020.05.31.125997 — synthetic biology — Posted on 2020-07-06
4013 The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites
Xu, F.; Jimenez-Gonzalez, A.; Einarsson, E.; Astvaldsson, A.; Peirasmaki, D.; Eckmann, L.; Andersson, J. O.; Svärd, S. G.; Jerlström-Hultqvist, J.
10.1101/870949 — evolutionary biology — Posted on 2020-07-06
4014 Optimizing spectral quality with quantum dots to enhance crop yield in controlled environments
Parrish, C. H.; Hebert, D.; Jackson, A.; Ramasamy, K.; McDaniel, H.; Giacomelli, G. A.; Bergren, M. R.
10.1101/2020.06.17.157487 — plant biology — Posted on 2020-07-06
4016 Developmental, cellular, and biochemical basis of transparency in the glasswing butterfly Greta oto
Pomerantz, A. F.; Siddique, R. H.; Cash, E. I.; Kishi, Y.; Pinna, C.; Hammar, K.; Gomez, D.; Elias, M.; Patel, N. H.
10.1101/2020.07.02.183590 — developmental biology — Posted on 2020-07-06
4018 Model-based design and analysis of life table experiments for insect vectors
Erguler, K.; Demirok, M. C.; Gunay, F.; Petric, M.; Kavran, M.; Petric, D. V.; Alten, B.
10.1101/2020.03.05.978684 — ecology — Posted on 2020-07-06
4019 A geometric basis for surface habitat complexity and biodiversity
Torres-Pulliza, D.; Dornelas, M. A.; Pizarro, O.; Bewley, M.; Blowes, S. A.; Boutros, N.; Brambilla, V.; Chase, T. J.; Frank, G.; Friedman, A.; Hoogenboom, M. O.; Williams, S.; Zawada, K. J.; Madin, J. S.
10.1101/2020.02.03.929521 — ecology — Posted on 2020-07-06
4020 Nitrergic Neurons of the Forepaw Representation in the Somatosensory and Motor Cortices
Guimaraes, B. d. P. P. F.; Curado, M. R.; Nogueira-Campos, A. A.; Houzel, J. C.; Gattass, R.
10.1101/2020.07.05.186635 — neuroscience — Posted on 2020-07-06
4022 Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza
Ohno, A.; Maita, N.; Tabata, T.; Nagano, H.; Arita, K.; Ariyoshi, M.; Uchida, T.; Nakao, R.; Ulla, A.; Sugiura, K.; Kishimoto, K.; Teshima-Kondo, S.; Nikawa, T.; Okumura, Y.
10.1101/2020.06.12.149229 — biophysics — Posted on 2020-07-06
4023 Early defects in lysosomal storage diseases disrupt excitatory synaptic transmission
de Britto Para de Aragao, C.; Bruno, L.; Bose, P.; Pan, X.; Han, C.; McPherson, P. S.; Freemantle, E.; Lacaille, J.-C.; Bonneil, E.; Thibault, P.; OLeary, C.; Bigger, B.; Morales, C. R.; DiCristo, G.; Pshezhetsky, A. V.
10.1101/2020.07.06.186809 — neuroscience — Posted on 2020-07-06
4026 Immune Inhibitor A Metalloproteases Contribute to Virulence in Bacillus Endophthalmitis
Livingston, E. T.; Mursalin, M. H.; Coburn, P. S.; Astley, R.; Miller, F. C.; Amayem, O.; Lereclus, D.; Callegan, M.
10.1101/2020.07.06.190264 — microbiology — Posted on 2020-07-06
4033 Optimised assembly of DNA-lipid nanostructures
Darley, E.; Ridone, P.; Singh, J. K. D.; Wickham, S. F.; Baker, M. A.
10.1101/2020.06.01.128686 — biophysics — Posted on 2020-07-06
4034 Inter-domain dynamics and fibrinolytic activity of matrix metalloprotease-1
Kumar, L.; Planas-Iglesias, J.; Harms, C.; Kamboj, S.; Wright, D.; Klein-Seetharaman, J.; Sarkar, S. K.
10.1101/853796 — biophysics — Posted on 2020-07-06
4036 A designed high-affinity peptide that hijacks microtubule-based transport
Cross, J. A.; Chegkazi, M. S.; Steiner, R. A.; Woolfson, D. N.; Dodding, M.
10.1101/2020.06.17.157255 — synthetic biology — Posted on 2020-07-06
4039 Zinc finger protein SALL4 functions through an AT-rich motif to regulate gene expression
Kong, N. R.; Bassal, M. A.; Tan, H. K.; Kurland, J. V.; Yong, K. J.; Young, J. J.; Yang, Y.; Li, F.; Lee, J.; Liu, Y.; Wu, C. S.; Stein, A.; Luo, H.; Silberstein, L.; Bulyk, M. L.; Tenen, D. G.; Chai, L.
10.1101/2020.07.03.186783 — molecular biology — Posted on 2020-07-06
4040 Modification of cell wall polysaccharide spatially controls cell division in Streptococcus mutans
Zamakhaeva, S.; Chaton, C. T.; Rush, J. S.; Ajay Castro, S.; Yarawsky, A. E.; Herr, A. B.; van Sorge, N. M.; Dorfmueller, H. C.; Frolenkov, G. I.; Korotkov, K. V.; Korotkova, N.
10.1101/2020.06.26.173716 — microbiology — Posted on 2020-07-06
4043 A rapid and simple method for assessing and representing genome sequences relatedness
Briand, M.; Bouzid, M.; Hunault, G.; Legeay, M.; Fischer-Le Saux, M.; Barret, M.
10.1101/569640 — genomics — Posted on 2020-07-06
4045 PICH function is required for organization of SUMOylated proteins on mitotic chromosomes
Hassebroek, V. A.; Park, H.; Pandey, N.; Lerbakken, B.; Aksenova, V.; Arnaoutov, A.; Dasso, M.; Azuma, Y.
10.1101/2020.02.06.937243 — cell biology — Posted on 2020-07-06
4046 Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity
Fellner, M.; Parakra, R.; McDonald, K. O.; Kass, I.; Jameson, G. N. L.; Wilbanks, S. M.; Ledgerwood, E. C.
10.1101/2020.06.14.151373 — biochemistry — Posted on 2020-07-06
4049 Poly(ADP-ribose) induces α-synuclein aggregation in neuronal-like cells andinteracts with phosphorylated α-synuclein in post mortem PD samples
Puentes, L. N.; Lengyel-Zhand, Z.; Lee, J. Y.; Hsieh, C.-J.; Schneider, M. E.; Edwards, K. J.; Luk, K. C.; Lee, V. M.- Y.; Trojanowski, J. Q.; Mach, R. H.
10.1101/2020.04.08.032250 — neuroscience — Posted on 2020-07-06
4050 Post-replicative pairing of sister ter regions in Escherichia coli involves multiple activities of MatP
Crozat, E.; Tardin, C.; Salhi, M.; Rousseau, P.; Lablaine, A.; Bertoni, T.; Holcman, D.; Sclavi, B.; Cicuta, P.; Cornet, F.
10.1101/755397 — microbiology — Posted on 2020-07-06
4051 Cross-validation of technologies for genotyping CYP2D6 and CYP2C19
Carvalho Henriques, B.; Yavorskyy, V.; Wang, Y.; Martens, K.; Behroozi Asl, B.; Carr, M.; Hague, J.; Hu, X.; Maier, W.; Dernovsek, M. Z.; Henigsberg, N.; Souery, D.; Cattaneo, A.; Mors, O.; Rietschel, M.; Lewis, C.; Pfeffer, G.; Bousman, C.; Aitchison, K. J.
10.1101/2019.12.24.870295 — genetics — Posted on 2020-07-06
4052 Evolution of metastases-associated fibroblasts in the lung microenvironment is driven by stage-specific transcriptional plasticity
Shani, O.; Raz, Y.; Monteran, L.; Megides, O.; Shacham, H.; Cohen, N.; Silverbush, D.; Levi-Galibov, O.; Avivi, C.; Sharan, R.; Madi, A.; Scherz-Shouval, R.; Barshack, I.; Tsarfaty, I.; Erez, N.
10.1101/778936 — cancer biology — Posted on 2020-07-06
4054 Cohesin-dockerin code in cellulosomal dual binding modes and its allosteric regulation by proline isomerization
Vera, A. M.; Galera-Prat, A.; Wojciechowski, M.; Rozycki, B.; Laurents, D. V.; Carrion-Vazquez, M.; Cieplak, M.; Tinnefeld, P.
10.1101/2019.12.19.882373 — biophysics — Posted on 2020-07-06
4057 The mycobacterial cell wall partitions the plasma membrane to organize its own synthesis
Garcia-Heredia, A.; Kado, T.; Sein, C. E.; Puffal, J.; Osman, S. H.; Judd, J.; Gray, T. A.; Morita, Y. S.; Siegrist, M. S.
10.1101/544338 — microbiology — Posted on 2020-07-06
4058 Epigenomic profiling of primate LCLs reveals the coordinated evolution of gene expression and epigenetic signals in regulatory architectures
Garcia-Perez, R.; Esteller-Cucala, P.; Mas, G.; Lobon, I.; Di Carlo, V.; Kuhlwilm, M.; Riera, M.; Navarro, A.; Blancher, A.; Di Croce, L.; Gomez-Skarmeta, J. L.; Juan, D.; Marques-Bonet, T.
10.1101/2019.12.18.872531 — evolutionary biology — Posted on 2020-07-06
4059 Virulent disease epidemics can increase host density by depressing foraging of hosts
Penczykowski, R. M.; Hall, S. R.; Shocket, M. S.; Housley Ochs, J.; Lemanski, B. C. P.; Sundar, H.; Duffy, M. A.
10.1101/2020.07.06.189878 — ecology — Posted on 2020-07-06
4060 Exploring the niche concept in a simple metaorganism
Deines, P.; Hammerschmidt, K.; Bosch, T. C. G.
10.1101/814798 — ecology — Posted on 2020-07-06
4061 PAK3 controls the tangential to radial migration switch of cortical interneurons by coordinating changes in cell shape and polarity
Viou, L.; Launay, P.; Rousseau, V.; Masson, J.; Pace, C.; Adelstein, R. S.; Ma, X.; Jia, Z.; Murakami, F.; Barnier, J.-V.; Metin, C.
10.1101/2020.07.06.168179 — developmental biology — Posted on 2020-07-06
4064 A bipartite transcription factor module controlling expression in the bundle sheath of Arabidopsis thaliana
Dickinson, P. J.; Knerova, J.; Szecowka, M.; Stevenson, S. R.; Burgess, S. J.; Mulvey, H.; Bagman, A.-M.; Gaudinier, A.; Brady, S. M.; Hibberd, J. M.
10.1101/380188 — plant biology — Posted on 2020-07-06
4066 LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation
Pischedda, F.; Cirnaru, M. D.; Ponzoni, L.; Sandre, M.; Biosa, A.; Carrion, M. P.; Marin, O.; Morari, M.; Pan, L.; Greggio, E.; Bandopadhyay, R.; Sala, M.; Piccoli, G.
10.1101/721266 — neuroscience — Posted on 2020-07-06
4067 Neural and behavioral correlates of episodic memory are associated with temporal discounting in older adults
Lempert, K. M.; Mechanic-Hamilton, D. J.; Xie, L.; Wisse, L. E. M.; de Flores, R.; Wang, J.; Das, S. R.; Yushkevich, P. A.; Wolk, D. A.; Kable, J. W.
10.1101/720250 — neuroscience — Posted on 2020-07-06
4068 Expanded CAG/CTG Repeats Resist Gene Silencing Mediated by Targeted Epigenome Editing
Yang, B.; Borgeaud, A. C.; Aeschbach, L.; Rodriguez-Lima, O.; Ruiz Buendia, G. A.; Cinesi, C.; Baubec, T.; Dion, V.
10.1101/368480 — molecular biology — Posted on 2020-07-06
4069 High-throughput cultivation of stable, diverse, fecal-derived microbial communities to model the intestinal microbiota
Aranda-Diaz, A.; Ng, K.; Thomsen, T.; Real-Ramirez, I.; Dahan, D.; Dittmar, S.; Gutierrez Gonzalez, C.; Chavez, T.; Vasquez, K. S.; Nguyen, T. H.; Yu, F. B.; Higginbottom, S. K.; Neff, N.; Elias, J. E.; Sonnenburg, J. L.; Huang, K. C.
10.1101/2020.07.06.190181 — microbiology — Posted on 2020-07-06
4070 Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2
Robinson, E. K.; Jagannatha, P.; Covarrubias, S.; Cattle, M.; Safavi, R.; Song, R.; Viswanathan, K.; Abu-Shumays, R.; Jain, M.; Cloonan, S. M.; Wakeland, E. K.; Akeson, M.; Brooks, A. N.; Carpenter, S.
10.1101/2020.07.06.190330 — immunology — Posted on 2020-07-06
4071 Single cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations
Zemmour, D.; Charbonnier, L.-M.; Leon, J.; Six, E.; Keles, S.; Delville, M.; Baris, S.; Zuber, J.; Chen, K.; Neven, B.; Garcia-Lloret, M. I.; Ruemmele, F.; Brugnara, C. B.; Cerf-Bensussan, N.; Rieux-Laucat, F.; Cavazzana, M.; Andre, I.; Chatila, T. A.; Mathis, D.; Benoist, C.
10.1101/2020.07.06.189589 — immunology — Posted on 2020-07-06
4072 Genome wide association study in 3,173 outbred rats identifies multiple loci for body weight, adiposity, and fasting glucose
Chitre, A. S.; Polesskaya, O.; Holl, K.; Gao, J.; Cheng, R.; Garcia Martinez, A.; George, T.; Gileta, A. F.; Han, W.; Horvath, A.; Hughson, A.; Ishiwari, K.; King, C. P.; Lamparelli, A.; Versaggi, C. L.; Martin, C.; St. Pierre, C. L.; Tripi, J. A.; Wang, T.; Bimschleger, H.; Chen, H.; Flagel, S. B.; Meyer, P.; Richards, J.; Robinson, T. E.; Palmer, A. A.; Solberg Woods, L. C.
10.1101/422428 — genetics — Posted on 2020-07-06
4075 Metabolomics and lipidomics in C. elegans using a single sample preparation
Molenaars, M.; Schomakers, B. V.; Elfrink, H. L.; Gao, A. W.; Vervaart, M. A. T.; Pras-Raves, M. L.; Luyf, A. C.; Smith, R. L.; Sterken, M. G.; Kammenga, J. E.; van Kampen, A. H. C.; Janssens, G. E.; Vaz, F. M.; van Weeghel, M.; Houtkooper, R. H.
10.1101/2020.07.06.190017 — biochemistry — Posted on 2020-07-06
4077 Role of sex and high fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer's disease
Robison, L. S.; Gannon, O. J.; Thomas, M. A.; Salinero, A. E.; Abi-Ghanem, C.; Poitelon, Y.; Belin, S.; Zuloaga, K. L.
10.1101/2020.07.06.189928 — neuroscience — Posted on 2020-07-06
4078 SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in kidney epithelial cells
Kim, J. Y.; Bai, Y.; Jayne, L. A.; Abdulkader, F.; Gandhi, M.; Parikh, S. V.; Song, M.-A.; Bajwa, A.; Pabla, N. S.
10.1101/2020.07.06.189829 — cell biology — Posted on 2020-07-06
4080 Gene Expression Network Analysis Provides Potential Targets Against SARS-CoV-2
Hernandez Cordero, A. I.; Li, X.; Yang, C. X.; Milne, S.; Bosse, Y. I.; Joubert, P.; Timens, W.; Berge, M. v. d.; Nickle, D.; Hao, K.; Sin, D. D.
10.1101/2020.07.06.182634 — genomics — Posted on 2020-07-06
4081 Effect of expression of human glucosylceramidase 2 isoforms on lipid profiles in COS-7 cells
Jatooratthawichot, P.; Talabnin, C.; Ngiwsara, L.; Rustam, Y. H.; Svasti, J.; Reid, G. E.; Ketudat Cairns, J. R.
10.1101/2020.07.06.190314 — biochemistry — Posted on 2020-07-06
4085 Identification of potent and safe antiviral therapeutic candidates against SARS-CoV-2
Xiao, X.; Wang, C.; Chang, D.; Wang, Y.; Dong, X.; Jiao, T.; Zhao, Z.; Ren, L.; Dela Cruz, C. S.; Sharma, L.; Lei, X.; Wang, J.
10.1101/2020.07.06.188953 — microbiology — Posted on 2020-07-06
4086 Animal Model Prescreening: Pre-exposure to SARS-CoV-2 impacts responses in the NHP model
Ricks, K. M.; Herbert, A. S.; Koehler, J. W.; Kuehnert, P. A.; Clements, T. L.; Shoemaker, C. J.; Kuehne, A. I.; O'Brien, C. M.; Coyne, S. R.; Delp, K. L.; Akers, K. S.; Dye, J. M.; Hooper, J. W.; Smith, J. M.; Kugelman, J. R.; Beitzel, B. F.; Gibson, K. M.; Johnston, S. C.; Minogue, T. D.
10.1101/2020.07.06.189803 — immunology — Posted on 2020-07-06
4088 Cardioids reveal self-organizing principles of human cardiogenesis
Hofbauer, P.; Jahnel, S.; Papai, N.; Giesshammer, M.; Tavernini, K.; Grdseloff, N.; Penc, M.; Meledeth, C.; Deyett, A.; Schmidt, C.; Ctortecka, C.; Salic, S.; Novatchkova, M.; Mendjan, S.
10.1101/2020.07.06.189431 — developmental biology — Posted on 2020-07-06
4092 Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection
Rathnasinghe, R.; Strohmeier, S.; Amanat, F.; Gillespie, V. L.; Krammer, F.; Garcia-Sastre, A.; Schotsaert, M.; Coughlan, L.; Uccellini, M. B.
10.1101/2020.07.06.190066 — microbiology — Posted on 2020-07-06
4093 Integration of high-density genetic mapping with transcriptome analysis uncovers numerous agronomic QTL and reveals candidate genes for the control of tillering in sorghum
Govindarajulu, R.; Henderson, A. N.; Xiao, Y.; Chaluvadi, S. R.; Mauro-Herrera, M.; Siddoway, M. L.; Whipple, C. J.; Bennetzen, J. L.; Devos, K. M.; Doust, A. N.; Hawkins, J. S.
10.1101/2020.07.06.189548 — genetics — Posted on 2020-07-06
4096 Structural and molecular basis of cross-seeding barriers in amyloids
Loquet, A.; Daskalov, A.; Coustou, V.; El Mammeri, N.; Berbon, M.; Andreas, L.; Bardiaux, B.; Stanek, J.; Noubhani, A.; Kauffmann, B.; Wall, J.; Pintacuda, G.; Saupe, S.; Habenstein, B.
10.1101/2020.07.06.188508 — biochemistry — Posted on 2020-07-06
4099 A chromosome level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution.
Warren, W. C.; Boggs, T. E.; Borowsky, R.; Carlson, B. M.; Ferrufino, E.; Gross, J. B.; Hiller, L.; Hu, Z.; Keene, A. C.; Kenzior, A.; Kowalko, J. E.; Tomlinson, C.; Kremitzki, M.; Lemieux, M. E.; Graves-Lindsay, T.; McGaugh, S. E.; Miller, J. T.; Mommersteeg, M.; Moran, R. L.; Peuss, R.; Rice, E.; Riddle, M. R.; Sifuentes-Romero, I.; Stanhope, B. A.; Tabin, C. J.; Thakur, S.; Yoshiyuki, Y.; Rohner, N.
10.1101/2020.07.06.189654 — genomics — Posted on 2020-07-06
4102 TLR7 ligation augments haematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling and enhanced differentiation
Pena, O. C.; Lubin, A.; Rowell, J.; Hockings, C. A.; Jung, Y.; Hoade, Y.; Dace, P.; Valdivia, L. E.; Tuschl, K.; Böiers, C.; Virgilio, M. C.; Richardson, S.; Payne, E. M.
10.1101/2020.07.06.175000 — cancer biology — Posted on 2020-07-06
4105 Neuronal autophagy regulates presynaptic neurotransmission by controlling the axonal endoplasmic reticulum
Kuijpers, M.; Kochlamazashvili, G.; Stumpf, A.; Puchkov, D.; Lucht, M. T.; Krause, E.; Schmitz, D.; Haucke, V.
10.1101/2020.07.06.189522 — neuroscience — Posted on 2020-07-06
4106 cAMP bursts control T cell directionality by actin cytoskeleton remodeling
Simao, M.; Regnier, F.; Taheraly, S.; Fraisse, A.; Tacine, R.; Fraudeau, M.; Benabid, A.; Feuillet, V.; Lambert, M.; Delon, J.; randriamampita, c.
10.1101/2020.07.06.189365 — immunology — Posted on 2020-07-06
4108 Numerical Model for Formation and Evolution of the Bleb
Feng, J.; Tang, L.; Liu, Z.; Dong, S.; Zhou, L.; Liu, Y.; Jiang, Z.
10.1101/2020.07.06.189738 — cell biology — Posted on 2020-07-06
4109 Dual-Mechanism Estrogen Receptor Inhibitors Reveal an Ensemble of Binding Modes for Robust Breast Cancer Antagonism
Min, J.; Nwachukwu, J. C.; Rangarajan, E.; Nettles, C. C.; Sanabria Guillen, V.; Ziegler, Y.; Yan, S.; Carlson, K.; Hou, Y.; Kim, S. H.; Novick, S.; Pascal, B.; Houtman, R.; Griffin, P.; Izard, T.; Katzenellenbogen, B.; Katzenellenbogen, J. A.; Nettles, K. W.
10.1101/2020.07.06.189977 — cancer biology — Posted on 2020-07-06
4110 Compression of quantification uncertainty for scRNA-seq counts
Van Buren, S.; Sarkar, H.; Srivastava, A.; Rashid, N. U.; Patro, R.; Love, M. I.
10.1101/2020.07.06.189639 — bioinformatics — Posted on 2020-07-06
4113 Faunistic study on the freshwater ciliates from Delhi, India
Abraham, J. S.; Gupta, R.; Somasundaram, S.; Naqvi, I.; Maurya, S.; Toteja, R.; Makhija, S.
10.1101/2020.07.06.189001 — zoology — Posted on 2020-07-06
4114 Sick Bats Stay Home Alone: Social distancing during the acute phase response in Egyptian fruit bats (Rousettus aegyptiacus)
Moreno, K. R.; Weinberg, M.; Harten, L.; Salinas Ramos, V. B.; Herrera M., L. G.; Czirjak, G. A.; Yovel, Y.
10.1101/2020.07.06.189357 — zoology — Posted on 2020-07-06
4115 Sleep Identification Enabled by Supervised Training Algorithms (SIESTA): An open-source platform for automatic sleep staging of rodent polysomnographic data
Caldart, C. S.; Sanchez, R. E. A.; Ben-Hamo, M.; Beck, A. I.; Weil, T. A.; Perez, J. G.; Kalume, F.; Brunton, B. W.; de la Iglesia, H. O.
10.1101/2020.07.06.186940 — neuroscience — Posted on 2020-07-06
4118 Global analysis of transcription start sites in the new ovine reference genome (Oar rambouillet v1.0)
Salavati, M.; Caulton, A.; Clark, R.; Gazova, I.; Smith, T. P. L.; Worley, K. C.; Cockett, N. E.; Archibald, A. L.; Clarke, S. M.; Murdoch, B. M.; Clark, E. L.; The Ovine FAANG Project Consortium,
10.1101/2020.07.06.189480 — genomics — Posted on 2020-07-06
4119 Prostate cancer peripheral blood NK cells show enhanced CD9, CD49a, CXCR4, CXCL8, MMP-9 production, and secrete monocyte-recruiting and polarizing factors
Baci, D.; Gallazzi, M.; Mortara, L.; Bosi, A.; Buono, G.; Naselli, A.; Guarneri, A.; Deho, F.; Capogrosso, P.; Albini, A.; Noonan, D. M.; Bruno, A.
10.1101/2020.07.06.189449 — cancer biology — Posted on 2020-07-06
4122 MDA5 is an essential vita-PAMP sensor necessary for host resistance against Aspergillus fumigatus
Wang, X.; Caffrey-Carr, A. K.; Liu, K.-w.; Espinosa, V.; Croteau, W.; Dhingra, S.; Rivera, A.; Cramer, R. A.; Obar, J. J.
10.1101/2020.07.06.182154 — immunology — Posted on 2020-07-06
4123 The human oral phageome is highly diverse and rich in jumbo phages
Carr, V. R.; Shkoporov, A. R.; Gomez-Cabrero, D.; Mullany, P.; Hill, C.; Moyes, D. L.
10.1101/2020.07.06.186817 — genomics — Posted on 2020-07-06
4124 Towards a taxonomically unbiased EU Biodiversity Strategy for 2030
Mammola, S.; Riccardi, N.; Prie', V.; Correia, R.; Cardoso, P.; Lopes-Lima, M.; Sousa, R.
10.1101/2020.07.06.189027 — ecology — Posted on 2020-07-06
4126 PaintSHOP enables the interactive design of transcriptome- and genome-scale oligonucleotide FISH experiments
Hershberg, E. A.; Close, J. L.; Camplisson, C. K.; Attar, S.; Chern, R.; Liu, Y.; Akilesh, S.; Nicovich, P. R.; Beliveau, B. J.
10.1101/2020.07.05.188797 — genomics — Posted on 2020-07-06
4127 Combination Treatment Optimization Using aPan-Cancer Pathway Model
Schmucker, R.; Farina, G.; Faeder, J.; Froehlich, F.; Saglam, A. S.; Sandholm, T.
10.1101/2020.07.05.184960 — systems biology — Posted on 2020-07-06
4130 Enabling in vivo Analysis Via Nanoparticle-mediated Intracellular Assay Probe Delivery: Using RAS as the Prototype
Chen, F.; Liu, Q.; Hilliard, T.; Wang, T.; Dong, Z.; Li, W.; Liang, H.; Gao, W.; Huang, L.; Wang, D.
10.1101/2020.07.05.188862 — biochemistry — Posted on 2020-07-06
4135 Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality
Levitan, A.; Gale, A. N.; Dalton, E. K.; Kozan, D. W.; Cunningham, K. W.; Sharan, R.; Berman, J.
10.1101/732552 — bioinformatics — Posted on 2020-07-06
4137 DNNBrain: a unifying toolbox for mapping deep neural networks and brains
Chen, X.; Zhou, M.; Gong, Z.; Xu, W.; Liu, X.; Huang, T.; Zhen, Z.; Liu, J.
10.1101/2020.07.05.188847 — neuroscience — Posted on 2020-07-06
4138 Single-cell analysis of severe COVID-19 patients reveals a monocyte-driven inflammatory storm attenuated by Tocilizumab
Guo, C.; Li, B.; Ma, H.; Wang, X.; Cai, P.; Yu, Q.; Zhu, L.; Jin, L.; Jiang, C.; Fang, J.; Liu, Q.; Zong, D.; Zhang, W.; Lu, Y.; Li, K.; Gao, X.; Fu, B.; Liu, L.; Ma, X.; Weng, J.; Wei, H.; Jin, T.; Lin, J.; Qu, K.
10.1101/2020.04.08.029769 — genomics — Posted on 2020-07-06
4139 Sexually dimorphic development of depression-related brain networks during healthy human adolescence
Dorfschmidt, L.; Bethlehem, R. A. I.; Seidlitz, J.; Vasa, F.; White, S. R.; Romero-Garcia, R.; Kitzbichler, M. G.; Aruldass, A.; Goodyer, I. M.; Fonagy, P.; Jones, P. B.; Dolan, R. J.; the NSPN Consortium, ; Harrison, N. A.; Vertes, P. E.; Bullmore, E. T.
10.1101/2020.07.06.184473 — neuroscience — Posted on 2020-07-06
4140 Tracking age differences in neural distinctiveness across representational levels
Kobelt, M.; Sommer, V. R.; Keresztes, A.; Werkle-Bergner, M.; Sander, M. C.
10.1101/2020.07.06.187187 — neuroscience — Posted on 2020-07-06
4141 Identification of oxygen-independent pathways for pyridine-nucleotide and Coenzyme-A synthesis in anaerobic fungi by expression of candidate genes in yeast
Perli, T.; Vos, A. M.; Bouwknegt, J.; Dekker, W. J.; Wiersma, S. J.; Mooiman, C.; Ortiz-Merino, R. A.; Daran, J.-M. G.; Pronk, J. T.
10.1101/2020.07.06.189415 — microbiology — Posted on 2020-07-06
4143 Identification of novel Rab46 effector proteins
Pedicini, L.; Wiktor, S. D.; Simmons, K. J.; McKeown, L.
10.1101/2020.07.06.189340 — cell biology — Posted on 2020-07-06
4145 Cotranslational folding of alkaline phosphatase in the periplasm of Escherichia coli
Elfagieh, R.; Karyolaimos, A.; Kemp, G.; deGier, J.-W.; von Heijne, G.; Kudva, R.
10.1101/2020.07.06.189464 — molecular biology — Posted on 2020-07-06
4150 Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells
Capelle, C.; Zeng, N.; Danileviciute, E.; Rodrigues, S. F.; Ollert, M.; Balling, R.; He, F. Q.
10.1101/2020.07.06.189456 — immunology — Posted on 2020-07-06
4151 Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant common complex traits
Pahl, M. C.; Doege, C. A.; Hodge, K. M.; Littleton, S. H.; Leonard, M. E.; Lu, S.; Rausch, R.; Pippin, J. A.; Bradfield, J. P.; Hammond, R. K.; Boehm, K.; Berkowitz, R. I.; Lasconi, C.; Su, C.; Chesi, A.; Johnson, M.; Wells, A. D.; Voight, B. F.; Leibel, R. L.; Cousminer, D. L.; Grant, S. F. A.
10.1101/2020.07.06.146951 — genomics — Posted on 2020-07-06
4152 Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture
Chia, R.; Sabir, M. S.; Bandres-Ciga, S.; Saez-Atienzar, S.; Reynolds, R. H.; Gustavsson, E.; Walton, R. L.; Ahmed, S.; Viollet, C.; Ding, J.; Makarious, M. B.; Diez-Fairen, M.; Portley, M. K.; Shah, Z.; Abramzon, Y.; Hernandez, D. G.; Blauwendraat, C.; Stone, D. J.; Eicher, J.; Parkkinen, L.; Ansorge, O.; Clark, L.; Honig, L. S.; Marder, K.; Lemstra, A.; St. George-Hyslop, P.; Londos, E.; Morgan, K.; Lashley, T.; Warner, T. T.; Jaunmuktane, Z.; Galasko, D.; Santana, I.; Tienari, P.; Myllykangas, L.; Oinas, M.; Cairns, N. J.; Morris, J. C.; Halliday, G. M.; Van Deerlin, V. M.; Trojanowski, J.
10.1101/2020.07.06.185066 — genomics — Posted on 2020-07-06
4154 Multilevel community assembly of the tadpole gut microbiome
Correa, D. T.; Rodriguez, D.; Emer, C.; Saenz, D.; Adams, C. K.; Schiesari, L. C.; Matz, M. V.; Leibold, M. A.
10.1101/2020.07.05.188698 — ecology — Posted on 2020-07-06
4155 Nanoscale Organization of FasL on DNA Origami as a Versatile Platform to Tune Apoptosis Signaling in Cells
Berger, R. M. L.; Weck, J. M.; Kempe, S. M.; Liedl, T.; Raedler, J. O.; Monzel, C.; Heuer-Jungemann, A.
10.1101/2020.07.05.187203 — biophysics — Posted on 2020-07-06
4159 Scalable Analysis of Authentic Viral Envelopeson FRONTERA
Gonzalez-Arias, F.; Reddy, T.; Stone, J.; Hadden-Perilla, J. A.; Perilla, J. R.
10.1101/2020.07.05.188367 — biophysics — Posted on 2020-07-06
4161 Self-incompatibility limits sexual reproduction rather than environmental conditions in an invasive aquatic plant
Portillo Lemus, L. O.; Bozec, M.; Harang, M.; Coudreuse, J.; Haury, J.; Stoeckel, S.; Barloy, D.
10.1101/2020.07.05.184267 — ecology — Posted on 2020-07-06
4162 Functional succinate dehydrogenase deficiency is a pathognomonic adverse feature of clear cell renal cancer
Aggarwal, R. K.; Zou, Y.; Luchtel, R. A.; Pradhan, K.; Ashai, N.; Ramachandra, N.; Albanese, J.; Yang, J.-i.; Wang, X.; Aluri, S.; Gordon, S.; Machha, V.; Tischer, A.; Aboumohamed, A.; Gartrell, B. A.; Hafizi, S.; Pullman, J.; Shenoy, N.
10.1101/2020.07.05.188433 — cancer biology — Posted on 2020-07-06
4167 Bidirectional regulation of cognitive and anxiety-like behaviors by dentate gyrus mossy cells in male and female mice
Botterill, J. J.; Vinod, K. Y.; Gerencer, K. J.; Teixeira, C. M.; LaFrancois, J. J.; Scharfman, H. E.
10.1101/2020.07.05.188664 — neuroscience — Posted on 2020-07-06
4168 Nitrergic Neurons of the Forepaw Representation in the Somatosensory and Motor Cortices
Guimaraes, B. d. P. P. F.; Curado, M. R.; Nogueira-Campos, A. A.; Houzel, J. C.; Gattass, R.
10.1101/2020.07.05.186635 — neuroscience — Posted on 2020-07-06
4175 Attenuated Anticipation of Social and Monetary Rewards in Autism Spectrum Disorders
Baumeister, S.; Moessnang, C.; Bast, N.; Hohmann, S.; Tillmann, J.; Goyard, D.; Charman, T.; Ambrosino, S.; Baron-Cohen, S.; Beckmann, C.; Boelte, S.; Bourgeron, T.; Rausch, A.; Crawley, D.; Dell'Acqua, F.; Dumas, G.; Durston, S.; Ecker, C.; Floris, D. L.; Frouin, V.; Hayward, H.; Holt, R.; Johnson, M. H.; Jones, E. J. H.; Lai, M.-C.; Lombardo, M. V.; Mason, L.; Oldehinkel, M.; Persico, T.; San Jos Caceres, A.; Wolfers, T.; Spooren, W.; Loth, E.; Murphy, D. G. M.; Buitelaar, J. K.; Tost, H.; Meyer-Lindenberg, A.; Banaschewski, T.; Brandeis, D.; AIMS-2-TRIALS group,
10.1101/2020.07.06.186650 — neuroscience — Posted on 2020-07-06
4179 Somatic variant analysis of linked-reads sequencing data with Lancet
Musunuri, R.; Arora, K.; Corvelo, A.; Shah, M.; Shelton, J.; Zody, M. C.; Narzisi, G.
10.1101/2020.07.04.158063 — bioinformatics — Posted on 2020-07-06
4180 Co-expressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts
Ramundo, S.; Asakura, Y.; Salomé, P. A. A.; Strenkert, D.; Boone, M.; Mackinder, L. C. M.; Takafuji, K.; Dinc, E.; Rahire, M.; Crèvecoeur, M.; Magneschi, L.; Schaad, O.; Hippler, M.; Jonikas, M. C.; Merchant, S.; Nakai, M.; Rochaix, J.-D.; Walter, P.
10.1101/2020.07.04.188128 — plant biology — Posted on 2020-07-06
4182 Cognitive Benefits of Exercise Interventions: An fMRI Activation Likelihood Estimation Meta-Analysis
Yu, Q.; Herold, F.; Becker, B.; KluGah-Brown, B.; Zhang, Y.; Perrey, S.; Veronese, N.; Muller, N. G.; Zou, L.; Kramer, A. F.
10.1101/2020.07.04.187401 — neuroscience — Posted on 2020-07-06
4183 The contribution of global mountains to the latitudinal diversity gradient
Tenorio, E. A.; Montoya, P.; Norden, N.; Rodriguez-Buritica, S.; Salgado-Negret, B.; Gonzalez, M. A.
10.1101/2020.07.04.188227 — ecology — Posted on 2020-07-06
4188 The D614G mutation of SARS-CoV-2 spike protein enhances viral infectivity
Hu, J.; He, C. L.; Gao, Q.; Zhang, G. J.; Cao, X. X.; Long, Q. X.; Deng, H. J.; Huang, L. Y.; Chen, J.; Wang, K.; Tang, N.; Huang, A. L.
10.1101/2020.06.20.161323 — microbiology — Posted on 2020-07-06
4195 Whole exome sequencing identifies novel DYT1 dystonia-associated genome variants as potential disease modifiers
Hu, C.-F.; Wu, S.-P.; Gant Luxton, G. W.; Lee, F.-C.; Hsu, C.-S.; Huang, S.-M.; Hong, J.-S.
10.1101/2020.03.15.993113 — genetics — Posted on 2020-07-05
4197 Removal of the extracellular matrix biases auditory cortical layer dynamics towards supragranular frequency integration
EL Tabbal, M.; Niekisch, H.; Henschke, J. J.; Budinger, E.; Frischknecht, R.; Deliano, M.; Happel, M. F. K.
10.1101/2020.05.04.076224 — neuroscience — Posted on 2020-07-05
4199 A free boundary mechanobiological model of epithelial tissues
Tambyah, T. A.; Murphy, R. J.; Buenzli, P. R.; Simpson, M. J.
10.1101/2020.07.02.185686 — biophysics — Posted on 2020-07-05
4200 A model of traumatic brain injury using human iPSC-derived cortical brain organoids
Lai, J. D.; Berlind, J. E.; Fricklas, G.; Sta Maria, N. S.; Jacobs, R. E.; Yu, V.; Ichida, J.
10.1101/2020.07.05.180299 — neuroscience — Posted on 2020-07-05
4204 Cadmium interference with iron sensing reveals transcriptional programs sensitive and insensitive to reactive oxygen species
McInturf, S. A.; Khan, M. A.; Gokul, A.; Castro-Guerrero, N. A.; Hoehner, R.; Li, J.; Margault, H.; Kunz, H. H.; Goggin, F. L.; Keyster, M.; Nechushtai, R.; Mittler, R.; Mendoza-Cozatl, D. G.
10.1101/2020.07.05.188649 — plant biology — Posted on 2020-07-05
4205 A probabilistic functional parcellation of human occipito-temporal cortex
Rosenke, M.; van Hoof, R.; van den Hurk, J.; Grill-Spector, K.; Goebel, R.
10.1101/2020.01.22.916239 — neuroscience — Posted on 2020-07-05
4206 Tau conformers in FTLD-MAPT undergo liquid-liquid phase separation and perturb the nuclear envelope
Kang, S.-G.; Han, Z. Z.; Daude, N.; McNamara, E.; Wohlgemuth, S.; Safar, J. G.; Mok, S.-A.; Westaway, D.
10.1101/2020.07.04.187997 — neuroscience — Posted on 2020-07-05
4207 Validation and Long-Term Follow Up of CD33 Off-Targets Predicted In Vitro and In Silico Using Error-Corrected Sequencing in Rhesus Macaques
AlJanahi, A. A.; Lazzarotto, C. R.; Chen, S.; Shin, T.-H.; Cordes, S.; Jabara, I.; Zhou, Y.; Young, D. J.; Lee, B.-C.; Yu, K.-R.; Li, Y.; Toms, B.; Tunc, I.; Hong, S. G.; Truitt, L.; Klermund, J.; Kim, M.; Cathomen, T.; Gill, S.; Tsai, S. Q.; Dunbar, C. E.
10.1101/2020.07.05.186858 — molecular biology — Posted on 2020-07-05
4208 Copper nanoparticles prompt the activity of estuarine denitrifying bacterial communities at relevant environmental concentrations
Costa, J.; Sousa, A. G. G.; Carneiro, A. C.; Mucha, A. P.; Almeida, C. M. R.; Magalhaes, C.; Baptista, M. S.
10.1101/2020.07.05.188334 — microbiology — Posted on 2020-07-05
4209 Novel algorithms for PFGE bacterial typing: Number of co-migrated DNA fragments, linking PFGE to WGS results and computer simulations for evaluation of PulseNet international typing protocols
Adam, I. E.-k. M.; Abdokashif, I.; Elrashid, A.; Bayoumi, H.; Musa, A.; Abdulgyom, E.; Mamoun, S.; Alnagar, S.; Mohammed, W.; El-khateeb, A.; Oshi, M.; El-bakri, F.
10.1101/2020.07.05.188623 — microbiology — Posted on 2020-07-05
4211 Isolation and chacterisation of Klebsiella phages for phage therapy
Townsend, E.; Kelly, L.; Gannon, L.; Muscatt, G.; Dunstan, R.; Michniewski, S.; Sapkota, H.; Kiljunen, S. J.; Kolsi, A.; Skurnik, M.; Lithgow, T.; MIllard, A. D.; Jameson, E.
10.1101/2020.07.05.179689 — microbiology — Posted on 2020-07-05
4215 The Torsin/ NEP1R1-CTDNEP1/ Lipin axis regulates nuclear envelope lipid metabolism for nuclear pore complex insertion
Jacquemyn, J.; Foroozandeh, J.; Vints, K.; Swerts, J.; Verstreken, P.; Gounko, N. V.; Gallego, S. F.; Goodchild, R. E.
10.1101/2020.07.05.188599 — cell biology — Posted on 2020-07-05
4216 Genetic background modifies vulnerability to glaucoma related phenotypes in Lmx1b mutant mice
Tolman, N.; Macalinao, D. G.; Kearney, A. L.; Macnicoll, K. H.; de Vries, W. N.; Jackson, I.; Cross, S. H.; Kizhatil, K. K.; Nair, S.; John, S. W.
10.1101/2020.07.05.188516 — genetics — Posted on 2020-07-05
4217 No evidence for long-range male sex pheromones in two malaria mosquitoes
Poda, S. B.; Buatois, B.; Lapeyre, B.; Dormont, L.; Diabate, A.; Gnankine, O.; Dabire, R. K.; Roux, O.
10.1101/2020.07.05.187542 — ecology — Posted on 2020-07-05
4219 Functional analysis of the fatty acid and alcohol metabolism of Pseudomonas putida using RB-TnSeq
Thompson, M.; Incha, M.; Pearson, A.; Schmidt, M.; Sharpless, W.; Eiben, C.; Cruz-Morales, P.; Blake-Hedges, J.; Liu, Y.; Adams, C.; Haushalter, R.; Krishna, R.; Lichtner, P.; Blank, L. M.; Mukhopadhyay, A.; Deutschbauer, A.; Shih, P.; Keasling, J. D.
10.1101/2020.07.04.188060 — microbiology — Posted on 2020-07-05
4221 Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens
Marquat, K. F.; Allam, A.; Janjuha, S.; Sintsova, A.; Villiger, L.; Frey, N.; Krauthammer, M.; Schwank, G.
10.1101/2020.07.05.186544 — genomics — Posted on 2020-07-05
4224 LiBis: An ultrasensitive alignment method for low-input bisulfite sequencing
Yin, Y.; Li, J.; Li, J.; Lee, M.; Zhao, S.; Guo, L.; Li, J.; Zhang, M.; Huang, Y.; Li, X.-N.; Sun, D.
10.1101/2020.05.14.096461 — bioinformatics — Posted on 2020-07-05
4225 Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of oxygen reactive species
Lepez, A.; Pirnay, T.; Denanglaire, S.; Perez-Morga, D.; Vermeersch, M.; Leo, O.; Andris, F.
10.1101/2020.03.06.978791 — immunology — Posted on 2020-07-05
4227 Repetitive blast promotes chronic aversion to neutral cues encountered in the peri-blast environment
Schindler, A. G.; Terry, G. E.; Wolden-Hanson, T.; Cline, M.; Park, M.; Lee, J.; Yagi, M.; Meabon, J. S.; Raskind, M. M.; Peskind, E. R.; Phillips, P. E.; Cook, D. G.
10.1101/2020.02.11.935718 — neuroscience — Posted on 2020-07-05
4228 A community-driven resource for genomic surveillance of Neisseria gonorrhoeae at Pathogenwatch
Sanchez-Buso, L.; Yeats, C. A.; Taylor, B.; Goater, R.; Underwood, A.; Abudahab, K.; Argimon, S.; Ma, K. C.; Mortimer, T. D.; Cole, M. J.; Grad, Y. H.; Martin, I.; Raphael, B. H.; Shafer, W. M.; Spiteri, G.; Town, K.; Wi, T.; Harris, S. R.; Unemo, M.; Aanensen, D. M.
10.1101/2020.07.03.186726 — genomics — Posted on 2020-07-05
4229 Ultra-Fast Homomorphic Encryption Models enable Secure Outsourcing of Genotype Imputation
Kim, M.; Harmanci, A. O.; Bossuat, J.-P.; Carpov, S.; Cheon, J. H.; Chillotti, I.; Cho, W.; Froelicher, D.; Gama, N.; Georgieva, M.; Hong, S.; Hubaux, J.-P.; Kim, D.; Lauter, K.; Ma, Y.; Ohno-Machado, L.; Sofia, H. J.; Son, Y.; Song, Y.; Troncoso-Pastoriza, J. R.; Jiang, X.
10.1101/2020.07.02.183459 — bioinformatics — Posted on 2020-07-05
4231 Stearoyl-CoA desaturase mediated monounsaturated fatty acid availability supports humoral immunity
Zhou, X.; Zhu, X.; Li, C.; Li, Y.; Ye, Z.; Shapiro, V. M.; Copland, J. A.; Hitosugi, T.; Bernlohr, D. A.; Sun, J.; Zeng, H.
10.1101/2020.04.22.028613 — immunology — Posted on 2020-07-05
4232 Genome-wide characterization deciphers distinct properties of major intrinsic proteins in six Phytophthora species
Azad, A. K.; Ahmed, J.; Hakim, A.; Hasan, M. M.; Alum, M. A.; Hasan, M.; Ishikawa, T.; Sawa, Y.
10.1101/394395 — bioinformatics — Posted on 2020-07-05
4235 Astroglial Calcium Signaling Encodes Sleep Need in Drosophila
Blum, I. D.; Keles, M. F.; Baz, E.-S.; Han, E.; Park, K.; Luu, S.; Issa, H.; Brown, M.; Ho, M. C. W.; Tabuchi, M.; Liu, S.; Wu, M.
10.1101/2020.07.04.187906 — neuroscience — Posted on 2020-07-05
4239 The Internal Structure of Metacommunities
Leibold, M. A.; Rudolf, J.; Blanchet, F. G.; De Meester, L.; Gravel, D.; Hartig, F.; Peres-Neto, P.; Shoemaker, L.; Chase, J.
10.1101/2020.07.04.187955 — ecology — Posted on 2020-07-05
4241 If the link missed: Could inflammatory skin disorders with barrier dysfunction increase the risk of COVID-19?
Xu, Q.; Chen, L.; Zhang, L.; Hu, M.; Wang, X.; Yang, Q.; Le, Y.; Xue, F.; Li, X.; Zheng, J.
10.1101/2020.06.30.181297 — pathology — Posted on 2020-07-05
4244 Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Aluminum Hydroxide Induces Protective Immunity and Reduces Immune Enhancement
Chen, W.-H.; Tao, X.; Agrawal, A.; Algaissi, A.; Peng, B.-H.; Pollet, J.; Strych, U.; Bottazzi, M. E.; Hotez, P. J.; Lustigman, S.; Du, L.; Jiang, S.; Tseng, C.-T. K.
10.1101/2020.05.15.098079 — immunology — Posted on 2020-07-05
4245 SARS-CoV-2 transmission chains from genetic data: a Danish case study
Bluhm, A.; Christandl, M.; Gesmundo, F.; Ravn Klausen, F.; Mancinska, L.; Steffan, V.; Stilck Franca, D.; Werner, A.
10.1101/2020.05.29.123612 — genomics — Posted on 2020-07-05
4246 Probabilistic programming: a powerful new approach to statistical phylogenetics
Ronquist, F.; Kudlicka, J.; Senderov, V.; Borgström, J.; Lartillot, N.; Lunden, D.; Murray, L.; Schön, T. B.; Broman, D.
10.1101/2020.06.16.154443 — evolutionary biology — Posted on 2020-07-05
4249 An innovative approach for HLA typing, molecular tumor testing and the validation of tumor exclusive antigens
Ghosh, M.; Bichmann, L.; Scheid, J.; Gueler, G.; Schuster, H.; Di Marco, M.; Marcu, A.; Beyer, M.; Nelde, A.; Freudenmann, L. K.; Muehlenbruch, L.; Loeffler, M. W.; Kohlbacher, O.; Rammensee, H.-G.; Stevanovic, S.
10.1101/2020.06.05.136754 — immunology — Posted on 2020-07-05
4250 Unravel the Mystery of NIC1-locus on Nicotine Biosynthesis Regulation in Tobacco
Sui, X.; Xie, H.; Tong, Z.; Zhang, H.; Song, Z.; Gao, Y.; Zhao, L.; Li, W.; Li, M.; Li, Y.; Li, Y.; Wang, B.
10.1101/2020.07.04.187922 — plant biology — Posted on 2020-07-04
4252 An early cell shape transition drives evolutionary expansion of the human forebrain
Benito-Kwiecinski, S.; Giandomenico, S. L.; Sutcliffe, M.; Riis, E. S.; Freire-Pritchett, P.; Kelava, I.; Wunderlich, S.; Martin, U.; Wray, G. A.; Lancaster, M. A.
10.1101/2020.07.04.188078 — evolutionary biology — Posted on 2020-07-04
4254 Global proteome and phosphoproteome alterations in third generation EGFR TKI resistance reveal drug targets to circumvent resistance
Zhang, X.; Maity, T.; Ross, K.; Qi, Y.; Cultraro, C.; Gao, S.; Nguyen, K. D.; Cowart, J.; Kirkali, F.; Wu, C.; Guha, U.
10.1101/2020.07.04.187617 — cancer biology — Posted on 2020-07-04
4256 Fine-scale Population Structure and Demographic History of Han Chinese Inferred from Haplotype Network of 111,000 Genomes
Lan, A.; Kang, K.; Tang, S.; Wu, X.; Wang, L.; Li, T.; Weng, H.; Deng, J.; WeGene Research Team, ; Zheng, Q.; Yao, X.; Chen, G.
10.1101/2020.07.03.166413 — genomics — Posted on 2020-07-04
4257 Peopling of Tibet Plateau and multiple waves of admixture of Tibetans inferred from both modern and ancient genome-wide data
Wang, M.; Zou, X.; Ye, H.-Y.; Liu, Y.; Wang, Z.; Liu, J.; Yao, H.; Chen, P.; Wang, F.; Tao, R.; Wang, S.; Wei, L.-H.; Tang, R.; Wang, C.-C.; He, G.
10.1101/2020.07.03.185884 — genetics — Posted on 2020-07-04
4258 Microstructures amplify carotenoid plumage signals in colorful tanagers
McCoy, D. E.; Shultz, A. J.; Vidoudez, C.; van der Heide, E.; Trauger, S. A.; Haig, D.
10.1101/799783 — evolutionary biology — Posted on 2020-07-04
4260 Measurement of hindered diffusion in complex geometries for high-speed single-molecule experiments
Bartsch, T. F.; Villasante, C. M.; Touré, A.; Firester, D. M.; Hengel, F. E.; Oswald, A.; Hudspeth, A. J.
10.1101/2020.07.04.187948 — biophysics — Posted on 2020-07-04
4264 Population Graph GNNs for Brain Age Prediction
Stankeviciute, K.; Azevedo, T.; Campbell, A.; Bethlehem, R. A. I.; Lio, P.
10.1101/2020.06.26.172171 — neuroscience — Posted on 2020-07-04
4265 Cell Type-Specific Chromatin Accessibility Analysis in the Mouse and Human Brain
Rocks, D.; Jaric, I.; Tesfa, L.; Greally, J. M.; Suzuki, M.; Kundakovic, M.
10.1101/2020.07.04.188094 — neuroscience — Posted on 2020-07-04
4267 CRISPR/Cas9-based silencing of the ATXN1 gene in Spinocerebellar ataxia type 1 (SCA1) fibroblasts
Salvatori, F.; Pappadà, M.; Sicurella, M.; Buratto, M.; Simioni, V.; Tugnoli, V.; Marconi, P.
10.1101/2020.07.04.187559 — neuroscience — Posted on 2020-07-04
4268 Evolution of DNA Replication Origin Specification and Gene Silencing Mechanisms
Hu, Y.; Tareen, A.; Sheu, Y.-J.; Ireland, W. T. T.; Speck, C.; Li, H.; Joshua-Tor, L.; Kinney, J. B.; Stillman, B.
10.1101/2020.07.04.187286 — molecular biology — Posted on 2020-07-04
4273 Pedigree-based measurement of the de novo mutation rate in the gray mouse lemur reveals a high mutation rate, few mutations in CpG sites, and a weak sex bias
Campbell, C. R.; Tiley, G. P.; Poelstra, J. W.; Hunnicutt, K. E.; Larsen, P. A.; Lee, H.-J.; Thorne, J. L.; dos Reis, M.; Yoder, A. D.
10.1101/724880 — evolutionary biology — Posted on 2020-07-04
4275 Connective-Tissue Growth Factor (CTGF/CCN2) Contributes to TGF-β1-Induced Lung Fibrosis
Yanagihara, T.; Chong, S. G.; Gholiof, M.; Lipson, K. E.; Zhou, Q.; Scallan, C.; Upagupta, C.; Tikkanen, J.; Keshavjee, S.; Ask, K.; Kolb, M. R.
10.1101/2020.07.04.187492 — cell biology — Posted on 2020-07-04
4276 SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain
Yurkovetskiy, L.; Pascal, K. E.; Tompkins-Tinch, C.; Nyalile, T.; Wang, Y.; Baum, A.; Diehl, W. E.; Dauphin, A.; Carbone, C.; Veinotte, K.; Egri, S. B.; Schaffner, S. F.; Lemieux, J. E.; Munro, J.; Sabeti, P. C.; Kyratsous, C.; Shen, K.; Luban, J.
10.1101/2020.07.04.187757 — microbiology — Posted on 2020-07-04
4277 A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike
Zhou, T.; Tsybovsky, Y.; Olia, A. S.; Gorman, J.; Rapp, M. A.; Cerutti, G.; Katsamba, P. S.; Nazzari, A.; Schon, A.; Wang, P. D.; Bimela, J.; Shi, W.; Teng, I.-T.; Zhang, B.; Boyington, J. C.; Chuang, G.-Y.; Sampson, J. M.; Sastry, M.; Stephens, T.; Stuckey, J.; Wang, S.; Friesner, R. A.; Ho, D. D.; Mascola, J. R.; Shapiro, L.; Kwong, P. D.
10.1101/2020.07.04.187989 — immunology — Posted on 2020-07-04
4278 Gender, race and parenthood impact academic productivity during the COVID-19 pandemic: from survey to action.
Staniscuaski, F.; Kmetzsch, L.; Zandona, E.; Reichert, F.; Soletti, R. C.; Ludwig, Z. M. C.; Lima, E. F.; Neumann, A.; Schwartz, I. V. D.; Mello-Carpes, P. B.; Tamajusuku, A. S. K.; Werneck, F. P.; Ricachenevsky, F. K.; Infanger, C.; Seixas, A.; Staats, C. C.; Oliveira, L.
10.1101/2020.07.04.187583 — scientific communication and education — Posted on 2020-07-04
4279 Evoked pain intensity representation is distributed across brain systems: A multistudy mega-analysis
Petre, B.; Kragel, P. A.; Atlas, L. Y.; Geuter, S.; Jepma, M.; Koban, L.; Krishnan, A.; Lopez-Sola, M.; Roy, M.; Woo, C.-W.; Wager, T. D.
10.1101/2020.07.04.182873 — neuroscience — Posted on 2020-07-04
4280 Publicly available hiPSC lines with extreme polygenic risk scores for modeling schizophrenia
Rehbach, K.; Zhang, H.; Das, D.; Sara Abdollahi, S.; Prorok, T.; Ghosh, S.; Weintraub, S.; Genovese, G.; Powell, S.; Lund, A.; Akbarian, S.; Eggan, K.; McCarroll, S. A.; Duan, J.; Avramopoulos, D.; Brennand, K. J.
10.1101/2020.07.04.185348 — genomics — Posted on 2020-07-04
4281 Deviation from baseline mutation burden provides powerful and robust rare-variants association test for complex diseases
Jiang, L.; Jiang, H.; Dai, S.; Chen, Y.; Song, Y.-Q.; Tang, C.; Wang, B.; Garcia-Barcelo, M.-M.; Tam, P.; Cherny, S.; Sham, P. C.; Li, M.
10.1101/2020.07.04.186619 — genetics — Posted on 2020-07-04
4283 Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation
Luciano, M.; Xue, S.-L.; De Vos, W. H.; Redondo Morata, L.; Surin, M.; Lafont, F.; Hannezo, E.; Gabriele, S.
10.1101/2020.07.04.187468 — biophysics — Posted on 2020-07-04
4288 Chronic exposure to IL6 leads to deregulation of glycolysis and fat accumulation in the zebrafish liver
Singh, M. K.; Jayarajan, R.; Varshney, S.; Upadrasta, S.; Singh, A.; Yadav, R.; Scaria, V.; Sengupta, S.; Shanmugam, D.; Shalimar, ; Sivasubbu, S.; Gandotra, S.; Sachidanandan, C.
10.1101/2020.07.04.162008 — molecular biology — Posted on 2020-07-04
4289 NCBP3 is a productive mRNP component
Dou, Y.; Barbosa, I.; Jiang, H.; Iasillo, C.; Molloy, K. R.; Schulze, W. M.; Cusack, S.; Schmid, M.; Le Hir, H.; LaCava, J.; Jensen, T. H.
10.1101/2020.07.04.184861 — molecular biology — Posted on 2020-07-04
4290 Allostery through DNA drives phenotype switching
Rosenblum, G.; Elad, N.; Rozenberg, H.; Wiggers, F.; Hofmann, H.
10.1101/2020.07.04.187450 — biophysics — Posted on 2020-07-04
4292 Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening
Kang, P. W.; Westerlund, A. M.; Shi, J.; McFarland White, K.; Dou, A. K.; Cui, A. H.; Silva, J. R.; Delemotte, L.; Cui, J.
10.1101/2020.07.04.187161 — biophysics — Posted on 2020-07-04
4293 The potential role of miR-21-3p in coronavirus-host interplay
Nersisyan, S.; Engibaryan, N.; Gorbonos, A.; Kirdey, K.; Makhonin, A.; Tonevitsky, A.
10.1101/2020.07.03.184846 — bioinformatics — Posted on 2020-07-04
4294 Combinatorial transcriptional profiling of mouse and human enteric neurons identifies shared and disparate subtypes in situ.
May-Zhang, A. A.; Tycksen, E.; Southard-Smith, A. N.; Deal, K. K.; Benthal, J. T.; Buehler, D. P.; Adam, M.; Simmons, A. J.; Monaghan, J. R.; Matlock, B. K.; Flaherty, D. K.; Potter, S.; Lau, K. S.; Southard-Smith, E. M.
10.1101/2020.07.03.187211 — neuroscience — Posted on 2020-07-04
4295 BAZ2A association with H3K14ac is required for the dedifferentiation of prostate cancer cells into a cancer stem-like state
Pena-Hernandez, R.; Aprigliano, R.; Frommel, S.; Pietrzak, K.; Steiger, S.; Roganowicz, M.; Bizzarro, J.; Santoro, R.
10.1101/2020.07.03.185843 — molecular biology — Posted on 2020-07-04
4296 Population-level differences in the neural substrates supporting Statistical Learning
Assaneo, M. F.; Orpella, J.; Ripolles, P.; Noejovich, L.; Lopez-Barroso, D.; de Diego Balaguer, R.; Poeppel, D.
10.1101/2020.07.03.187260 — neuroscience — Posted on 2020-07-04
4297 BRG1 promotes transcriptional patterns that are permissive to proliferation in cancer cells
Giles, K. A.; Gould, C. M.; Achinger-Kawecka, J.; Page, S. G.; Kafer, G.; Luu, P.-L.; Cesare, A. J.; Clark, S. J.; Taberlay, P. C.
10.1101/2020.07.03.187385 — molecular biology — Posted on 2020-07-04
4298 An integrative oncogene-dependency map identifies unique vulnerabilities of oncogenic RIT1 in lung cancer
Vichas, A.; Nkinsi, N. T.; Riley, A.; Parrish, P. C. R.; Duke, F.; Chen, J.; Watson, J.; Rees, M.; Lee, J. K.; Piccioni, F.; Hatch, E. M.; Berger, A. H.
10.1101/2020.07.03.187310 — cancer biology — Posted on 2020-07-04
4299 PD-L1 glycosylation and its impact on binding to clinical antibodies
Benicky, J.; Sanda, M.; Brnakova Kennedy, Z.; Grant, O. C.; Woods, R. J.; Zwart, A.; Goldman, R.
10.1101/2020.07.03.187179 — cancer biology — Posted on 2020-07-04
4301 A Large-Scale Internal Validation Study of Unsupervised Virtual Trichrome Staining Technologies on Non-alcoholic Steatohepatitis Liver Biopsies
Levy, J.; Azizgolshani, N.; Andersen, M.; Suriawinata, A. A.; Liu, X.; Lisovsky, M.; Ren, B.; Christensen, B.; Vaickus, L. J.
10.1101/2020.07.03.187237 — pathology — Posted on 2020-07-04
4304 ZeroCostDL4Mic: an open platform to simplify access and use of Deep-Learning in Microscopy
Chamier, L. v.; Laine, R. F.; Jukkala, J.; Spahn, C.; Lerche, M.; Hernandez-perez, S.; Mattila, P.; Karinou, E.; Holden, S.; Can Solak, A.; Krull, A.; Buchholz, T.-O.; Jug, F.; Royer, L. A.; Heilemann, M.; Jacquemet, G.; Henriques, R.
10.1101/2020.03.20.000133 — bioinformatics — Posted on 2020-07-04
4305 Zinc Determines Dynamical Properties and Aggregation Kinetics of Human Insulin
Pounot, K.; Grime, G. W.; Longo, A.; Zamponi, M.; Noferini, D.; Cristiglio, V.; Seydel, T.; Garman, E. F.; Weik, M.; Fodera, V.; Schiro, G.
10.1101/2020.07.02.184903 — biophysics — Posted on 2020-07-04
4306 Arabidopsis Poly(ADP-ribose)-binding protein RCD1 interacts with Photoregulatory Protein Kinases in nuclear bodies
Vainonen, J. P.; Shapiguzov, A.; Krasensky-Wrzaczek, J.; De Masi, R.; Gossens, R.; Danciu, I.; Battchikova, N.; Jonak, C.; Wirthmueller, L.; Wrzaczek, M.; Kangasjärvi, J.
10.1101/2020.07.02.184937 — plant biology — Posted on 2020-07-04
4307 BonVision - an open-source software to create and control visual environments
Lopes, G.; Farrell, K.; Horrocks, E. A. B.; Lee, C.-Y.; Morimoto, M. M.; Muzzu, T.; Papanikolaou, A.; Rodrigues, F. R.; Wheatcroft, T.; Zucca, S.; Solomon, S. G.; Saleem, A. B.
10.1101/2020.03.09.983775 — neuroscience — Posted on 2020-07-04
4308 Synergy between Wsp1 and Dip1 may initiate assembly of endocytic actin networks
Balzer, C. J.; James, M. L.; Helgeson, L. A.; Sirotkin, V.; Nolen, B. J.
10.1101/2020.07.03.187120 — biochemistry — Posted on 2020-07-04
4309 Optogenetics in Sinorhizobium meliloti enables spatial control of exopolysaccharide production and biofilm structure
Pirhanov, A.; Bridges, C. M.; Goodwin, R. A.; Guo, Y.-S.; Furrer, J.; Shor, L. M.; Gage, D. J.; Cho, Y. K.
10.1101/2020.07.03.187138 — synthetic biology — Posted on 2020-07-04
4310 Deep learning and computer vision will transform entomology
Hoye, T. T.; Arje, J.; Bjerge, K.; Hansen, O. L.; Iosifidis, A.; Leese, F.; Mann, H.; Meissner, K.; Melvad, C.; Raitoharju, J.
10.1101/2020.07.03.187252 — ecology — Posted on 2020-07-04
4312 Activation of bone marrow adaptive immunity in type 2 diabetes: rescue by co-stimulation modulator Abatacept
Santopaolo, m.; Sullivan, N.; Thomas, A.; Alvino, V. V.; Nicholson, L.; Gu, Y.; Spinetti, G.; Kallikourdis, M.; Blom, A.; Madedddu, P.
10.1101/2020.07.03.187088 — immunology — Posted on 2020-07-04
4317 Topographic gradients of intrinsic dynamics across neocortex
Shafiei, G.; Markello, R. D.; Vos de Wael, R.; Bernhardt, B. C.; Fulcher, B. D.; Misic, B.
10.1101/2020.07.03.186916 — neuroscience — Posted on 2020-07-04
4320 Microstructural characterization and validation of a 3D printed phantom for diffusion MRI
Mushtaha, F. N.; Kuehn, T. K.; El-Deeb, O.; Rohani, S. A.; Helpard, L. W.; Moore, J.; Ladak, H.; Moehring, A.; Baron, C. A.; Khan, A. R.
10.1101/2020.07.02.185397 — neuroscience — Posted on 2020-07-04
4321 A photosynthesis operon in the chloroplast genome drives speciation in evening primroses
Zupok, A.; Kozul, D.; Schoettler, M. A.; Niehoerster, J.; Garbsch, F.; Liere, K.; Malinova, I.; Bock, R.; Greiner, S.
10.1101/2020.07.03.186627 — evolutionary biology — Posted on 2020-07-04
4322 Zinc finger protein SALL4 functions through an AT-rich motif to regulate heterochromatin formation
Kong, N. R.; Bassal, M. A.; Tan, H. K.; Kurland, J. V.; Yong, K. J.; Young, J. J.; Yang, Y.; Li, F.; Lee, J.; Liu, Y.; Wu, C. S.; Stein, A.; Luo, H.; Silberstein, L.; Bulyk, M. L.; Tenen, D. G.; Chai, L.
10.1101/2020.07.03.186783 — molecular biology — Posted on 2020-07-04
4325 Integrating deep learning with microfluidics for biophysical classification of sickle red blood cells
Praljak, N.; Iram, S.; Goreke, U.; Singh, G.; Hill, A.; Gurkan, U. A.; Hinczewski, M.
10.1101/2020.07.01.181545 — biophysics — Posted on 2020-07-04
4326 A combined microphysiological-computational omics approach in dietary protein evaluation
Jochems, P. G.; Keusters, W. R.; America, A. H. P.; Rietveld, P. C.; Bastiaan-Net, S.; Ariens, R. M.; Tomassen, M. M. M.; Lewis, F.; Li, Y.; Westphal, K. G.; Garssen, J.; Wichers, H. J.; Van Bergenhenegouwen, J.; Masereeuw, R.
10.1101/2020.07.03.184689 — bioengineering — Posted on 2020-07-04
4329 Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes
Gastaldello, A.; Ramarathinam, S. H.; Bailey, A.; Owen, R. S.; Turner, S. C.; Kontouli, N.; Elliott, T. J.; Skipp, P. J. S.; Purcell, A. W.; Siddle, H. V.
10.1101/2020.07.03.184416 — immunology — Posted on 2020-07-04
4334 Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role
Dumont, A.-A.; Dumont, L.; Zhou, D.; Giguere, H.; Pileggi, C.; Harper, M.-E.; Blondin, D. P.; Scott, M. S.; Auger-Messier, M.
10.1101/2020.07.03.186999 — physiology — Posted on 2020-07-04
4336 Impact of parasitic lifestyle and different types of centromere organization on chromosome and genome evolution in the plant genus Cuscuta
Neumann, P.; Oliveira, L.; Cizkova, J.; Jang, T.-S.; Klemme, S.; Novak, P.; Stelmach, K.; Koblizkova, A.; Dolezel, J.; Macas, J.
10.1101/2020.07.03.186437 — genomics — Posted on 2020-07-04
4337 Primate heart regeneration via migration and fibroblast repulsion by human heart progenitors
Schneider, C.; Foo, K. S.; De Angelis, M. T.; Santamaria, G.; Reiter, F.; Dorn, T.; Bähr, A.; Tsoi, Y. L.; Hoppmann, P.; My, I.; Meier, A.; Jurisch, V.; Hornaschewitz, N.; Schwarz, S.; Lu, K.; Tomasi, R.; Sudhop, S.; Parrotta, E.; Gaspari, M.; Cuda, G.; Klymiuk, N.; Dendorfer, A.; Krane, M.; Kupatt, C.; Sinnecker, D.; Moretti, A.; R. Chien, K. R.; Laugwitz, K.-L.
10.1101/2020.07.03.183798 — cell biology — Posted on 2020-07-04
4340 The Roles of Space and Stochasticity in Computational Simulations of Cellular Biochemistry: Quantitative Analysis and Qualitative Insights
Johnson, M. E.; Chen, A.; Faeder, J.; Henning, P.; Moraru, I. I.; Meier-Schellersheim, M.; Murphy, R. F.; Prustel, T.; Theriot, J. A.; Uhrmacher, A.
10.1101/2020.07.02.185595 — systems biology — Posted on 2020-07-04
4341 Large-scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines
Zhao, W.; Li, J.; Chen, M.-J.; Ju, Z.; Nesser, N.; Johnson-Camacho, K.; Boniface, C.; Lawrence, Y.; Pande, N.; Davies, M.; Herlyn, M.; Muranen, T.; Zervantonakis, I.; Von Euw, E.; Schultz, A.; Kumar, S.; Korkut, A.; Spellman, P.; Akbani, R.; Slamon, D.; Gray, J.; Brugge, J.; Lu, Y.; Mills, G.; Liang, H.
10.1101/2020.07.03.186908 — systems biology — Posted on 2020-07-04
4342 NAD+ Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy
Chiao, Y. A.; Chakraborty, A.; Light, C.; Tian, R.; Sadoshima, J.; Shi, X.; Gu, H.; Lee, C. F.
10.1101/2020.07.03.183111 — physiology — Posted on 2020-07-04
4343 Hyperkalemia, not apoptosis, accurately predicts insect chilling injury
Carrington, J.; Andersen, M. K.; Brzezinski, K.; MacMillan, H. A.
10.1101/2020.07.03.186759 — physiology — Posted on 2020-07-04
4344 Biophysical modeling of the neural origin of EEG and MEG signals
Naess, S.; Halnes, G.; Hagen, E.; Hagler, D. J.; Dale, A.; Einevoll, G. T.; Ness, T. V.
10.1101/2020.07.01.181875 — neuroscience — Posted on 2020-07-04
4348 Comparative poly(A)+ RNA interactome capture of fission yeast RNA exosome mutants reveals insights into RNA biogenesis
Birot, A.; Kilchert, C.; Kus, K.; Priest, E.; Alwash, A.; Heo, D.-H.; Castello, A.; Mohammed, S.; Vasilieva, L.
10.1101/2020.07.01.181719 — genomics — Posted on 2020-07-04
4349 Chromosome fusions shape an ancient UV sex chromosome system
Carey, S. B.; Jenkins, J.; Payton, A. C.; Shu, S.; Lovell, J. T.; Maumus, F.; Sreedasyam, A.; Tiley, G. P.; Fernandez-Pozo, N.; Barry, K.; Chen, C.; Wang, M.; Lipzen, A.; Daum, C.; Saski, C. A.; McBreen, J. C.; Conrad, R. E.; Kollar, L. M.; Olsson, S.; Huttunen, S.; Landis, J. B.; Burleigh, G.; Wickett, N. J.; Johnson, M. G.; Rensing, S. A.; Grimwood, J.; Schmutz, J.; McDaniel, S.
10.1101/2020.07.03.163634 — evolutionary biology — Posted on 2020-07-04
4350 Metabolic versatility of the nitrite-oxidizing bacterium Nitrospira marina and its proteomic response to oxygen-limited conditions
Bayer, B.; Saito, M. A.; McIlvin, M. R.; Luecker, S.; Moran, D. M.; Lankiewicz, T. S.; Dupont, C. L.; Santoro, A. E.
10.1101/2020.07.02.185504 — ecology — Posted on 2020-07-04
4352 Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm
Dziedzicka, D.; Tewary, M.; Keller, A.; Tilleman, L.; Prochazka, L.; Östblom, J.; Couvreu De Deckersberg, E.; Markouli, C.; Franck, S.; Van Nieuwerburgh, F.; Spits, C.; Zandstra, P. W.; Sermon, K.; Geens, M.
10.1101/2020.07.03.186932 — cell biology — Posted on 2020-07-04
4353 Viability and mitochondrial bioenergetic functions in human colon cancer cells are not affected by treatment with peptides mtCPP1, UPF25, mtgCPP, and mtCPP1gHO
Timohhina, N.; Cerrato, C. P.; Kurrikoff, K.; Chekulayev, V.; Aid-Vanakova, J.; Puurand, M.; Tepp, K.; Shevchuk, I.; Langel, U.; Kaambre, T.
10.1101/2020.07.03.185967 — cancer biology — Posted on 2020-07-04
4358 Heart Snapshot: a broadly validated smartphone measure of VO2max for collection of real world data
Webster, D. E.; Tummalacherla, M.; Higgins, M.; Wing, D.; Ashley, E.; Kelly, V. E.; McConnell, M. V.; Muse, E. D.; Olgin, J.; Mangravite, L.; Godino, J.; Kellen, M.; Omberg, L.
10.1101/2020.07.02.185314 — bioengineering — Posted on 2020-07-04
4360 Upregulation and cell specificity of C4 genes are derived from ancestral C3 gene regulatory networks
SIngh, P.; Stevenson, S. R.; Reyna-Llorens, I.; Reeves, G.; Schreier, T. B.; Hibberd, J. M.
10.1101/2020.07.03.186395 — plant biology — Posted on 2020-07-04
4364 Rapid Evolution of Parasite Resistance via Improved Recognition and Accelerated Immune Activation and Deactivation
Hund, A. K.; Fuess, L. E.; Kenney, M. L.; Maciejewski, M. F.; Marini, J. M.; Shim, K. C.; Bolnick, D. I.
10.1101/2020.07.03.186569 — evolutionary biology — Posted on 2020-07-04
4365 Genome reduction is associated with bacterial pathogenicity across different scales of temporal and ecological divergence
Murray, G. G. R.; Charlesworth, J.; Miller, E. L.; Casey, M. J.; Lloyd, C. T.; Gottschalk, M.; Tucker, A. W.; Welch, J. J.; Weinert, L. A.
10.1101/2020.07.03.186684 — evolutionary biology — Posted on 2020-07-04
4366 End-to-end Bayesian analysis of 14C dates reveals new insights into lowland Maya demography
Price, M. H.; Capriles, J. M.; Hoggarth, J. A.; Bocinsky, K.; Ebert, C. E.; Jones, J. H.
10.1101/2020.07.02.185256 — ecology — Posted on 2020-07-04
4367 Ultra-Fast Homomorphic Encryption Models enable Secure Outsourcing of Genotype Imputation
Kim, M.; Harmanci, A. O.; Bossuat, J.-P.; Carpov, S.; Cheon, J. H.; Chilotti, I.; Cho, W.; Froelicher, D.; Gama, N.; Georgieva, M.; Hong, S.; Hubaux, J.-P.; Kim, D.; Lauter, K.; Ma, Y.; Ohno-Machado, L.; Sofia, H. J.; Son, Y.; Song, Y.; Troncoso-Pastoriza, J. R.; Jiang, X.
10.1101/2020.07.02.183459 — bioinformatics — Posted on 2020-07-04
4368 Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness
Sanz Perl, Y.; Pallavicini, C.; Ipina, I. P.; Demertzi, A.; Bonhomme, V.; Martial, C.; Panda, R.; Annen, J.; Ibanez, A.; Kringelbach, M.; Deco, G.; Laufs, H.; Sitt, J.; Laureys, S.; Tagliazucchi, E.
10.1101/2020.07.02.185157 — neuroscience — Posted on 2020-07-04
4370 Maternal immune activation during pregnancy alters early neurobehavioral development in nonhuman primate offspring
Vlasova, R. M.; Iosif, A.-M.; Ryan, A. M.; Murai, T.; Lesh, T. A.; Rowland, D. J.; Bennett, J.; Hogrefe, C. E.; Maddock, R. J.; Gandal, M. J.; Geschwind, D. H.; Schumann, C. M.; Van de Water, J.; McAllister, A. K.; Carter, C. S.; Styner, M. A.; Amaral, D. G.; Bauman, M. D.
10.1101/2020.07.02.185363 — neuroscience — Posted on 2020-07-04
4372 Cerebellar degeneration reduces memory resilience after extended training
Hulst, T.; Mamlins, A.; Frens, M.; Chang, D.-I.; Goericke, S. L.; Timmann, D.; Donchin, O.
10.1101/2020.07.03.185959 — neuroscience — Posted on 2020-07-03
4375 Expectations and blind spots for structural variation detection from short-read alignment and long-read assembly
Zhao, X.; Collins, R. L.; Lee, W.-P.; Weber, A. M.; Jun, Y.; Zhu, Q.; Weisburd, B.; Huang, Y.; Audano, P. A.; Wang, H.; Walker, M.; Lowther, C.; Fu, J.; Gerstein, M. B.; Devine, S. E.; Marschall, T.; Korbel, J. O.; Eichler, E. E.; Chaisson, M. J. P.; Lee, C.; Mills, R. E.; Brand, H.; Talkowski, M. E.
10.1101/2020.07.03.168831 — genomics — Posted on 2020-07-04
4376 Peopling of Tibet Plateau and multiple waves of admixture of Tibetans inferred from both modern and ancient genome-wide data
Wang, M.; Zou, X.; Ye, H.-Y.; Liu, Y.; Wang, Z.; Liu, J.; Yao, H.; Chen, P.; Wang, F.; Tao, R.; Wang, S.; Wei, L.-H.; Tang, R.; Wang, C.-C.; He, G.
10.1101/2020.07.03.185884 — genetics — Posted on 2020-07-03
4379 Red-light is an environmental effector for mutualism between begomovirus and its vector whitefly
Zhao, P.; Zhang, X.; Gong, Y.; Xu, D.; Wang, N.; Sun, Y.; Liu, S.; Deng, X.; Kliebenstein, D.; zhou, x.; Fang, R.; Ye, J.
10.1101/2020.07.03.186262 — plant biology — Posted on 2020-07-03
4380 On the origin of photoperiod non-responsiveness in barley
Sharma, R.; Shaaf, S.; Neumann, K.; Guo, Y.; Mascher, M.; David, M.; Al-Yassin, A.; Özkan, H.; Blake, T.; Hübner, S.; Castaneda-Alvarez, N. P.; Grando, S.; Ceccarelli, S.; Baum, M.; Graner, A.; Coupland, G.; Pillen, K.; Weiss, E.; Mackay, I. J.; Powell, W.; Kilian, B.
10.1101/2020.07.02.185488 — plant biology — Posted on 2020-07-03
4381 Efficient and stable metabarcoding sequencing from DNBSEQ-G400 sequencer examined by large fungal community analysis
Sun, X.; Wang, J.; Fang, C.; Li, J.; Han, M.; Wei, X.; Zheng, H.; Luo, X.; Gong, M.; Xiao, L.; Hu, Y.; Song, Z.
10.1101/2020.07.02.185710 — microbiology — Posted on 2020-07-03
4384 The influence of biofilm formation on carbapenem resistance in clinical Klebsiella pneumoniae infections: phenotype vs genome-wide analysis
Devanga Ragupathi, N. K.; Muthuirulandi Sethuvel, D. P.; Triplicane Dwarakanathan, H.; Murugan, D.; Umashankar, Y.; Monk, P. N.; Karunakaran, E.; Veeraraghavan, B.
10.1101/2020.07.03.186130 — genomics — Posted on 2020-07-03
4388 Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in Saccharomyces cerevisiae
Schummer, A.; Maier, R.; Gabay-Maskit, S.; Hansen, T.; Muehlhaeuser, W. W. D.; Suppanz, I.; Fadel, A.; Schuldiner, M.; Girzalsky, W.; Oeljeklaus, S.; Zalckvar, E.; Erdmann, R.; Warscheid, B.
10.1101/2020.07.03.186833 — cell biology — Posted on 2020-07-03
4389 Investigating the drivers of macro-fungal dark diversity using LiDAR
Valdez, J.; Brunbjerg, A. K.; Flojgaard, C.; Dalby, L.; Clausen, K. K.; Pärtel, M.; Pfeifer, N.; Hollaus, M.; Wimmer, M. H.; Ejrnaes, R.; Moeslund, J. E.
10.1101/2020.07.02.185553 — ecology — Posted on 2020-07-03
4391 A global resource for genomic predictions of antimicrobial resistance and surveillance of Salmonella Typhi at Pathogenwatch
Argimon, S.; Yeats, C. A.; Goater, R. J.; Abudahab, K.; Taylor, B.; Underwood, A.; Sanchez-Buso, L.; Wong, V. K.; Dyson, Z. A.; Nair, S.; Park, S. E.; Marks, F.; Page, A. J.; Keane, J. A.; Baker, S.; Holt, K. E.; Dougan, G.; Aanensen, D. M.
10.1101/2020.07.03.186692 — genomics — Posted on 2020-07-03
4394 Modulation of triple artemisinin-based combination therapy pharmacodynamics by Plasmodium falciparum genotype
Ansbro, M. R.; Itkin, Z.; Chen, L.; Zahoranszky-Kohalmi, G.; Amaratunga, C.; Miotto, O.; Peryea, T.; Hobbs, C. V.; Suon, S.; S, J. M.; Dondorp, A. M.; van der Pluijm, R. W.; Wellems, T.; Simeonov, A.; Eastman, R. T.
10.1101/2020.07.03.187039 — microbiology — Posted on 2020-07-03
4395 The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type-2 immunity-independent inhibition of food intake
van der Zande, H. J. P.; Gonzalez, M. A.; de Ruiter, K.; Wilbers, R.; Garcia-Tardon, N.; van Huizen, M.; van Noort, K.; Pelgrom, L. R.; Lambooij, J. M.; Zawistowska-Deniziak, A.; Otto, F.; Ozir-Fazalalikhan, A.; van Willigen, D.; Welling, M.; Poles, J.; van Leeuwen, F.; Hokke, C. H.; Schots, A.; Yazdanbakhsh, M.; Loke, P.; Guigas, B.
10.1101/2020.07.03.186254 — immunology — Posted on 2020-07-03
4396 Upgraded CRISPR/Cas9 Tools for Tissue-Specific Mutagenesis in Drosophila
Koreman, G. T.; Hu, Q.; Xu, Y.; Zhang, Z.; Allen, S. E.; Wolfner, M. F.; Wang, B.; Han, C.
10.1101/2020.07.02.185652 — genetics — Posted on 2020-07-03
4399 A tyrosine kinase protein interaction map reveals targetable EGFR network oncogenesis in lung cancer
Kaushik, S.; Haderk, F.; Zhao, X.; Hu, H.-M.; Shah, K. N.; Jang, G. M.; Olivas, V.; Nanjo, S.; Masto, V. B.; Ciznadija, D.; Sloma, I.; Gross, E.; Weinrich, S. L.; Johnson, J. R.; Bivona, T. G.; Krogan, N. J.; Bandyopadhyay, S.
10.1101/2020.07.02.185173 — cancer biology — Posted on 2020-07-03
4401 ApoC-III helical structure determines its ability to bind plasma lipoproteins and inhibit Lipoprotein Lipase-mediated triglyceride lipolysis.
Vitali, C.; Stankov, S.; Khetarpal, S. A.; Millar, J.; Mayne, L.; Englander, S. W.; Hand, N. J.; Lund-Katz, S.; Phillips, M. C.; Rader, D. J.
10.1101/2020.07.02.183178 — biochemistry — Posted on 2020-07-03
4403 Human ANKLE1 is a nuclease specific for branched DNA
Song, J.; Freeman, A. D. J.; Knebel, A.; Gartner, A.; Lilley, D. M. J.
10.1101/2020.07.03.186551 — biochemistry — Posted on 2020-07-03
4408 Replication dynamics of recombination-dependent replication forks
Naiman, K.; Campillo-Funollet, E.; Watson, A. T.; Budden, A.; Miyabe, I.; Carr, A.
10.1101/2020.07.03.186676 — molecular biology — Posted on 2020-07-03
4411 Class A Penicillin-Binding Protein-mediated cell wall synthesis promotes structural integrity during peptidoglycan endopeptidase insufficiency
Murphy, S. G.; Murtha, A. N.; Zhao, Z.; Alvarez, L.; Diebold, P.; Shin, J.-H.; VanNieuwenhze, M. S.; Cava, F.; Doerr, T.
10.1101/2020.07.03.187153 — microbiology — Posted on 2020-07-03
4415 Dissimilar conservation pattern in hepatitis C virus mutant spectra, consensus sequences, and data banks
Garcia-Crespo, C.; Soria, M. E.; Gallego, I.; De Avila, A. I.; Martinez-Gonzalez, B.; Vazquez-Sirvent, L.; Gomez, J.; Briones, C.; Gregori, J.; Quer, J.; Perales, C.; Domingo, E.
10.1101/2020.07.03.186171 — microbiology — Posted on 2020-07-03
4417 Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation
Queval, C. J.; Fearns, A.; Botella, L.; Smyth, A.; Schnettger, L.; Mitermite, M.; Wooff, E.; Villareal-Ramos, B.; Garcia-Gimenez, W.; Heunis, T.; Trost, M.; Werling, D.; Salguero, F. J.; Gordon, S. V.; Gutierrez, M.
10.1101/2020.07.02.185744 — microbiology — Posted on 2020-07-03
4422 Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in continuous culture
Zhang, J.; Huang, Y.; Yoon, J.-Y.; Kemmitt, J.; Wright, C.; Schneider, K.; Sphabmixay, P.; Hernandez-Gordillo, V.; Holcomb, S. J.; Bhushan, B. M.; Rohatgi, G.; Benton, K.; Carpenter, D.; Kester, J.; Eng, G.; Breault, D. T.; Yilmaz, O.; Taketani, M.; Voigt, K. A.; Carrier, R. L.; Trumper, D. L.; Griffith, L. G.
10.1101/2020.07.02.185082 — bioengineering — Posted on 2020-07-03
4423 A community-driven resource for genomic surveillance of Neisseria gonorrhoeae at Pathogenwatch
Sanchez-Buso, L.; Yeats, C. A.; Taylor, B.; Goater, R.; Underwood, A.; Abudahab, K.; Argimon, S.; Ma, K. C.; Mortimer, T. D.; Cole, M. J.; Grad, Y. H.; Martin, I.; Raphael, B. H.; Shafer, W. M.; Aanensen, D. M.; Spiteri, G.; Town, K.; Wi, T.; Harris, S. R.; Unemo, M.
10.1101/2020.07.03.186726 — genomics — Posted on 2020-07-03
4425 A CRISPR-based SARS-CoV-2 diagnostic assay that is robust against viral evolution and RNA editing
Ooi, K. H.; Tay, J. W. D.; Teo, S. Y.; Liu, M. M.; Kaewsapsak, P.; Jin, S.; Gao, Y.-G.; Tan, M. H.
10.1101/2020.07.03.185850 — genomics — Posted on 2020-07-03
4427 Nucleosome composition regulates the histone H3 tail conformational ensemble and accessibility
Morrison, E. A.; Baweja, L.; Poirier, M. G.; Weresczczynski, J.; Musselman, C. A.
10.1101/2020.06.26.172072 — biophysics — Posted on 2020-07-03
4428 Map of SARS-CoV-2 spike epitopes not shielded by glycans.
Sikora, M.; von Bülow, S.; Blanc, F. E. C.; Gecht, M.; Covino, R.; Hummer, G.
10.1101/2020.07.03.186825 — biophysics — Posted on 2020-07-03
4429 Fast quantitative analysis of timsTOF PASEF data with MSFragger and IonQuant
Yu, F.; Haynes, S. E.; Teo, G. C.; Avtonomov, D. M.; Polasky, D. A.; Nesvizhskii, A. I.
10.1101/2020.03.19.999334 — bioinformatics — Posted on 2020-07-03
4430 Domestication of the emblematic white cheese-making fungus Penicillium camemberti and its diversification into two varieties
Ropars, J.; Didiot, E.; Rodriguez de la Vega, R. C.; Bennetot, B.; Coton, M.; Poirier, E.; Coton, E.; Snirc, A.; Le Prieur, S.; Giraud, T.
10.1101/2020.02.12.945238 — evolutionary biology — Posted on 2020-07-03
4431 Pathway-specific deregulation of striatal excitatory synapses in LRRK2 mutations
Chen, C.; Soto, G.; Bannon, N.; Kang, S.; Kozorovitskiy, Y.; Parisiadou, L.
10.1101/2020.01.03.894410 — neuroscience — Posted on 2020-07-03
4432 Robust and sensitive detection of SARS-CoV-2 using PCR based methods
Park, C.; Lee, J.; Hassan, Z. U.; Ku, K. B.; Kim, S. J.; Kim, H. G.; Park, E. C.; Park, G.-S.; Park, D.; Baek, S.-H.; Park, D.; Lee, J.; Jeon, S.; Kim, S.; Lee, C.-S.; Yoo, H. M.; Kim, S.
10.1101/2020.07.03.186304 — microbiology — Posted on 2020-07-03
4434 Spatial engineering of E. coli with addressable phase-separated RNAs
Guo, H.; Ryan, J. C.; Mallet, A.; Song, X.; Pabst, V.; Decrulle, A.; Lindner, A. B.
10.1101/2020.07.02.182527 — synthetic biology — Posted on 2020-07-03
4437 SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
Giuliani, G.; Vumbaca, S.; Fuoco, C.; Gargioli, C.; Giorda, E.; Massacci, G.; Palma, A.; Reggio, A.; Riccio, F.; Vinci, M.; Castagnoli, L.; Cesareni, G.
10.1101/2020.05.14.096438 — cell biology — Posted on 2020-07-03
4438 Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy
Humbert, M.; Seiler, K.; Mosimann, S.; Rentsch, V.; McKenna, S. L.; Tschan, M. P.
10.1101/2020.01.29.924555 — cancer biology — Posted on 2020-07-03
4441 SUV39 SET domains mediate crosstalk of heterochromatic histone marks
Stirpe, A.; Guidotti, N.; Northall, S.; Kilic, S.; Hainard, A.; Vadas, O.; Fierz, B.; Schalch, T.
10.1101/2020.06.30.177071 — molecular biology — Posted on 2020-07-03
4442 Diversification of the restriction modification system of Streptococcus pyogenes through its acquisition of mobile elements
Ota, A.; Nishiuchi, Y.; Nakanishi, N.; Iijima, Y.; Iwamoto, T.; Osaki, K.; Ogura, Y.; Toyoda, A.; Suzuki, Y.; Hayashi, T.; Ohge, H.; Mori, H.; Ato, M.; MARUYAMA, F.
10.1101/2020.06.30.179317 — microbiology — Posted on 2020-07-03
4444 Phylogenomic analysis reveals the basis of adaptation of Pseudorhizobium species to extreme environments
Lassalle, F.; Dastgheib, S. M. M.; Zhao, F.-J.; Zhang, J.; Verbarg, S.; Fruhling, A.; Brinkmann, H.; Osborne, T. H.; Sikorski, J.; Balloux, F.; Didelot, X.; Santini, J. M.; Petersen, J.
10.1101/690347 — microbiology — Posted on 2020-07-03
4445 Linking the dynamics of chromatin occupancy and transcription with predictive models
Tran, T. Q.; Tripuraneni, V.; MacAlpine, H.; Mitra, S.; MacAlpine, D. M.; Hartemink, A. J.
10.1101/2020.06.28.176545 — genomics — Posted on 2020-07-03
4447 MAGIC: Mosaic Analysis by gRNA-Induced Crossing-over
Allen, S. E.; Koreman, G. T.; Sarkar, A.; Wang, B.; Wolfner, M. F.; Han, C.
10.1101/2020.06.26.174045 — genetics — Posted on 2020-07-03
4448 Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes
Lotta, L. A.; Pietzner, M.; Stewart, I. D.; Wittemans, L. B.; Li, C.; Bonelli, R.; Raffler, J.; Biggs, E. K.; Oliver-Williams, C.; Auyeung, V. P. W.; Luan, J.; Wheeler, E.; Paige, E.; Surendran, P.; Michelotti, G. A.; Scott, R. A.; Burgess, S.; Zuber, V.; Sanderson, E.; Koulman, A.; Imamura, F.; Forouhi, N.; Khaw, K.-T.; Griffin, J. L.; Wood, A. M.; Kastenmüller, G.; Danesh, J.; Butterworth, A. S.; Gribble, F. M.; Reimann, F.; Bahlo, M.; Fauman, E.; Wareham, N. J.; Langenberg, C.
10.1101/2020.02.03.932541 — genetics — Posted on 2020-07-03
4449 NeuroPAL: A Neuronal Polychromatic Atlas of Landmarks for Whole-Brain Imaging in C. elegans
Yemini, E.; Lin, A.; Nejatbakhsh, A.; Varol, E.; Sun, R.; Mena, G. E.; Samuel, A. D.; Paninski, L.; Venkatachalam, V.; Hobert, O.
10.1101/676312 — neuroscience — Posted on 2020-07-03
4451 Population Graph GNNs for Brain Age Prediction
Stankeviciute, K.; Azevedo, T.; Campbell, A.; Bethlehem, R. A. I.; Lio, P.
10.1101/2020.06.26.172171 — neuroscience — Posted on 2020-07-03
4452 Ecological implications of removing a concrete gas platform in the North Sea
Coolen, J. W. P.; Bittner, O.; Driessen, F. M. F.; van Dongen, U.; Siahaya, M. S.; de Groot, W.; Mavraki, N.; Bolam, S. G.; van der Weide, B.
10.1101/2020.04.16.044263 — ecology — Posted on 2020-07-03
4454 Spatial Variation of Microtubule Depolymerization in Large Asters Suggests Regulation by MAP Depletion
Ishihara, K.; Decker, F.; Caldas, P.; Pelletier, J.; Loose, M.; Brugues, J.; Mitchison, T.
10.1101/2020.06.26.172783 — cell biology — Posted on 2020-07-03
4455 Hierarchical coupling between ATP hydrolysis and Hsp90's client binding site
Wolf, S.; Sohmen, B.; Hellenkamp, B.; Thurn, J.; Stock, G.; Hugel, T.
10.1101/2020.02.15.950725 — biophysics — Posted on 2020-07-03
4457 Enhanced genome integrity maintenance and few directly stress-mitigating alterations in extreme habitat-adapted Arabidopsis halleri
Lee, G.; Quintana, J.; Ahmadi, H.; Janina, N.; Preite, V.; Syllwasschy, L.; Anderson, J. E.; Pietzenuk, B.; Kraemer, U.
10.1101/859249 — plant biology — Posted on 2020-07-03
4458 Immediate and long-term effects of transcranial direct-current stimulation in the mouse primary somatosensory cortex
Sanchez-Leon, C. A.; Cordones, I.; Ammann, C.; Ausin, J. M.; Gomez-Climent, M. A.; Carretero-Guillen, A.; Sanchez-Garrido Campos, G.; Gruart, A.; Delgado-Garcia, J. M.; Cheron, G.; Medina, J. F.; Marquez-Ruiz, J.
10.1101/2020.07.02.184788 — neuroscience — Posted on 2020-07-03
4459 On the objectivity, reliability, and validity of deep learning enabled bioimage analyses
Segebarth, D.; Griebel, M.; Stein, N.; R. von Collenberg, C.; Martin, C.; Fiedler, D.; Comeras, L. B.; Sah, A.; Schoeffler, V.; Lueffe, T.; Duerr, A.; Gupta, R.; Sasi, M.; Lillesaar, C.; Lange, M. D.; Tasan, R. O.; Singewald, N.; Pape, H.-C.; Flath, C. M.; Blum, R.
10.1101/473199 — neuroscience — Posted on 2020-07-03
4461 Spectral graph theory efficiently characterises ventilation heterogeneity in lung airway networks.
Whitfield, C. A.; Latimer, P.; Horsley, A.; Wild, J. M.; Collier, G. J.; Jensen, O. E.
10.1101/2020.04.15.042416 — biophysics — Posted on 2020-07-03
4462 Multi-scale Genomic Inference using Biologically Annotated Neural Networks
Demetci, P.; Cheng, W.; Darnell, G.; Zhou, X.; Ramachandran, S.; Crawford, L.
10.1101/2020.07.02.184465 — genetics — Posted on 2020-07-03
4463 Epitope-Based Peptide Vaccine Design Against Fructose Bisphosphate Aldolase of Candida Glabrata: An Immunomics Approach
Elhasan, L. M.; Hassan, M. B.; Elhassan, R. M.; Abdelrhman, F.; Salih, E. A.; Hassan, A. I.; Mohamed, A. A.; Osman, H. S.; Khalil, M. S.; Alsafi, A.; Idris, A. B.; Hassan, M. A.
10.1101/2020.07.03.180430 — bioinformatics — Posted on 2020-07-03
4467 Directed evolution reveals the mechanism of HitRS signal transduction in Bacillus anthracis
Skaar, E. P.; Pi, H.; Chu, M.; Ivan, S.; Latario, C.; Toth, A.; Carlin, S.; Hillebrand, G.; Lin, H.; Reppart, J.; Stauff, D. L.
10.1101/2020.07.03.185868 — biochemistry — Posted on 2020-07-03
4472 Fine-scale Population Structure and Demographic History of Han Chinese Inferred from Haplotype Network of 111,000 Genomes
Lan, A.; Kang, K.; Tang, S.; Wu, X.; Wang, L.; Li, T.; Weng, H.; Deng, J.; WeGene Research Team, ; Zheng, Q.; Yao, X.; Chen, G.
10.1101/2020.07.03.166413 — genomics — Posted on 2020-07-03
4473 Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
Long, M. D.; Singh, P. K.; Llimos, G.; Jacobi, J. J.; Rowsam, A. M.; Rosario, S. R.; Kirk, J.; Affronti, H. C.; Campbell, M. J.; Smiraglia, D.
10.1101/2020.07.02.182758 — cancer biology — Posted on 2020-07-03
4474 Reduced type-A carbohydrate-binding module interactions to cellulose leads to improved endocellulase activity
Nemmaru, B.; Ramirez, N.; Farino, C. J.; Yarbrough, J. M.; Kravhcenko, N.; Chundawat, S. P. S.
10.1101/2020.07.02.183293 — biochemistry — Posted on 2020-07-03
4475 Amino acid substitutions associated with treatment failure of hepatitis C virus infection
Soria, M. E.; Garcia-Crespo, C.; Martinez-Gonzalez, B.; Vazquez-Sirvent, L.; Lobo-Vega, R.; de Avila, A. I.; Gallego, I.; Chen, Q.; Garcia-Cehic, D.; Llorens-Revull, M.; Briones, C.; Gomez, J.; Ferrer-Orta, C.; Verdaguer, N.; Gregori, J.; Rodriguez-Frias, F.; Buti, M.; Esteban, J. I.; Domingo, E.; Quer, J.; Perales, C.
10.1101/2020.07.03.180240 — microbiology — Posted on 2020-07-03
4478 Explainable AI reveals key changes in skin microbiome associated with menopause, smoking, aging and skin hydration
Carrieri, A. P.; Haiminen, N.; Maudsley-Barton, S.; Gardiner, L.-J.; Murphy, B.; Mayes, A.; Paterson, S.; Grimshaw, S.; Winn, M.; Shand, C.; Rowe, W.; Hawkins, S.; MacGuire-Flanagan, A.; Tazzioli, J.; Kenny, J.; Parida, L.; Hoptroff, M.; Pyzer-Knapp, E. O.
10.1101/2020.07.02.184713 — bioinformatics — Posted on 2020-07-03
4479 HIF-stabilization prevents delayed fracture healing
Lang, A.; Helfmeier, S.; Stefanowski, J.; Kuppe, A.; Sunkara, V.; Pfeiffenberger, M.; Wolter, A.; Damerau, A.; Hemmati-Sadeghi, S.; Ringe, J.; Haag, R.; Hauser, A. E.; Loehning, M.; Perka, C.; Duda, G. N.; Hoff, P.; Schmidt-Bleek, K.; Gaber, T.; Buttgereit, F.
10.1101/2020.07.02.182832 — bioengineering — Posted on 2020-07-03
4481 Genetic ancestry changes in Stone to Bronze Age transition in the East European plain
Saag, L.; Vasilyev, S. V.; Varul, L.; Kosorukova, N. V.; Gerasimov, D. V.; Oshibkina, S. V.; Griffith, S. J.; Solnik, A.; Saag, L.; D'Atanasio, E.; Metspalu, E.; Reidla, M.; Rootsi, S.; Kivisild, T.; Scheib, C. L.; Tambets, K.; Kriiska, A.; Metspalu, M.
10.1101/2020.07.02.184507 — evolutionary biology — Posted on 2020-07-03
4482 Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth
Nandadasa, S.; Szafron, J. M.; Pathak, V.; Murtada, S.-I.; Craft, C. M.; O'Donnell, A.; Norvik, C.; Hughes, C.; Caterson, B.; Domowicz, M. S.; Schwartz, N. B.; Tran-Lundmark, K.; Veigl, M.; Sedwick, D.; Philipson, E. H.; Humphrey, J. D.; Apte, S. S.
10.1101/2020.07.02.184978 — developmental biology — Posted on 2020-07-03
4483 ANTAGONISTIC ROLES FOR ATAXIN-2 STRUCTURED AND DISORDEREDDOMAINS IN RNP CONDENSATION
Singh, A.; Hulsmeier, J.; Kandi, A. R.; Pothapragada, S. S.; Hillebrand, J.; Petrauskas, A.; Agrawal, K.; RT, K.; Thiagarajan, D.; Vijayraghavan, K.; Ramaswami, M.; Bakthavachalu, B.
10.1101/2020.07.02.184796 — neuroscience — Posted on 2020-07-03
4484 KDM6B promotes oncogenic CDK4/6-pRB-E2F pathway via maintaining enhancer activation in high-risk neuroblastoma
D'oto, A.; Fang, J.; Jin, H.; Xu, B.; Singh, S.; Mullasseril, A.; Jones, V.; Von Butler, X.; Cooke, B.; Hu, D.; Shohet, J.; Murphy, A.; Davidoff, A.; YANG, J.
10.1101/2020.07.02.184986 — cancer biology — Posted on 2020-07-03
4485 Is structure based drug design ready for selectivity optimization?
Albanese, S. K.; Chodera, J. D.; Volkamer, A.; Keng, S.; Abel, R.; Wang, L.
10.1101/2020.07.02.185132 — biophysics — Posted on 2020-07-03
4489 Fully Implanted Prostheses for Musculoskeletal Limb Reconstruction after Amputation: An In Vivo Feasibility Study
Hall, P.; Bratcher, S.; Stubbs, R. C.; Rifkin, R.; Grzeskowiak, R.; Burton, B.; Greenacre, C.; Stephenson, S.; Anderson, D.; Crouch, D.
10.1101/2020.07.02.184994 — bioengineering — Posted on 2020-07-03
4492 SMAD6 Integrates Endothelial Cell Homeostatic Flow Responses Downstream of Notch
Ruter, D. L.; Liu, Z.; Ngo, K. M.; X, S.; Marvin, A.; Buglak, D. B.; Kidder, E. J.; Bautch, V. L.
10.1101/2020.07.02.184820 — cell biology — Posted on 2020-07-03
4494 Mistargeting of secretory cargo in retromer-deficient cells
Neuman, S. D.; Terry, E. L.; Selegue, J. E.; Cavanagh, A. T.; Bashirullah, A.
10.1101/2020.07.02.185660 — developmental biology — Posted on 2020-07-03
4497 Senescent cell death as an aging resistance mechanism in naked mole-rat
Kawamura, Y.; Oka, K.; Takamori, M.; Sugiura, Y.; Oiwa, Y.; Fujioka, S.; Homma, S.; Miyawaki, S.; Narita, M.; Fukuda, T.; Suematsu, M.; Bono, H.; Okano, H.; Miura, K.
10.1101/2020.07.02.155903 — cell biology — Posted on 2020-07-03
4500 Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB
Thys, A.; Trillet, K.; Rosinska, S.; Gayraud, A.; Douanne, T.; Danger, Y.; Renaud, C.; Antigny, L.; Lavigne, R.; Pineau, C.; Com, E.; Verite, F.; Gavard, J.; Bidere, N.
10.1101/2020.07.02.184085 — immunology — Posted on 2020-07-03
4502 Mendelian imputation of parental genotypes for genome-wide estimation of direct and indirect genetic effects
Young, A. I.; Nehzati, S. M.; Lee, C.; Benonisdottir, S.; Cesarini, D.; Benjamin, D. J.; Turley, P.; Kong, A.
10.1101/2020.07.02.185199 — genetics — Posted on 2020-07-03
4503 USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer
Rossi, F. A.; Enrique Steinberg, J. H.; Calvo Roitberg, E. H.; Joshi, M.; Pandey, A.; Abba, M.; Dufrusine, B.; Buglioni, S.; De Laurenzi, V.; Sala, G.; Lattanzio, R.; Espinosa, J. M.; Rossi, M.
10.1101/2020.07.01.181883 — cancer biology — Posted on 2020-07-03
4504 A multi-network comparative analysis of transcriptome and translatome in cardiac remodeling
Boileau, E.; Doroudgar, S.; Riechert, E.; Jürgensen, L.; Ho, T. C.; Katus, H. A.; Völkers, M.; Dieterich, C.
10.1101/2020.07.01.181743 — bioinformatics — Posted on 2020-07-03
4507 Analysis of Complex DNA Rearrangements During Early Stages of HAC Formation
Pesenti, E.; Liskovykh, M.; Okazaki, K.; Mallozzi, A.; Reid, C.; Abad, M. A.; Jeyaprakash, A. A.; Kouprina, N.; Larionov, V.; Earnshaw, W. C.
10.1101/2020.07.02.184408 — synthetic biology — Posted on 2020-07-03
4509 CYFIP2 containing WAVE complexes inhibit cell migration
Polesskaya, A.; Boutillon, A.; Wang, Y.; Lavielle, M.; Vacher, S.; Schnitzler, A.; Molinie, N.; Rocques, N.; Fokin, A.; Bieche, I.; David, N. B.; Gautreau, A. M.
10.1101/2020.07.02.184655 — cell biology — Posted on 2020-07-03
4512 Phase separation enables heterochromatin domains to do mechanical work
Williams, J. F.; Surovtsev, I. V.; Schreiner, S. M.; Nguyen, H.; Hu, Y.; Mochrie, S.; King, M. C.
10.1101/2020.07.02.184127 — cell biology — Posted on 2020-07-03
4514 Evolution of a sex megachromosome
Conte, M. A.; Clark, F. B.; Roberts, R. B.; Xu, L.; Tao, W.; Zhou, Q.; Wang, D.; Kocher, T. D.
10.1101/2020.07.02.182808 — evolutionary biology — Posted on 2020-07-03
4516 Molecular architecture of the developing mouse brain
La Manno, G.; Siletti, K.; Furlan, A.; Gyllborg, D.; Vinsland, E.; Langseth, C.; Khven, I.; Johnsson, A.; Nilsson, M.; Lonnerberg, P.; Linnarsson, S.
10.1101/2020.07.02.184051 — developmental biology — Posted on 2020-07-03
4521 Deep learning-based classification of resting-state fMRI independent-component analysis
Nozais, V.; Boutinaud, P.; Verrecchia, V.; Gueye, M.-F.; Herve, P. Y.; Tzourio, C.; Mazoyer, B.; Joliot, M.
10.1101/2020.07.02.183772 — neuroscience — Posted on 2020-07-03
4522 FUNGAL DYSBIOSIS CORRELATES WITH THE DEVELOPMENT OF TUMOUR-INDUCED CACHEXIA IN MICE
Jabes, D. L.; de Maria, Y. N. L. F.; Aciole Barbosa, D.; Santos, K. B. N. H.; Alencar, V. C.; Carvalho, L. d. M.; Humberto, A. C.; Batista, M. L.; Costa de Oliveira, R.; Menegidio, F. B.; Nunes, L. R.
10.1101/2020.06.29.171397 — microbiology — Posted on 2020-07-03
4524 Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses
Kolmus, K.; Erdenebat, P.; Stewig, B.; Szymanska, E.; Goryca, K.; Szumera-Cieckiewicz, A.; Dereziska-Wolek, E.; Brewinska-Olchowik, M.; Piwocka, K.; Prochorec-Sobieszek, M.; Mikula, M.; Miaczynska, M.
10.1101/2020.07.02.183954 — cell biology — Posted on 2020-07-03
4525 Activation of prodynorphin neurons in the dorsomedial hypothalamus inhibits food intake and promotes positive valence
Imoto, D.; Yamamoto, I.; Matsunaga, H.; Yonekura, T.; Lee, M.-L.; KATO, K. X.; Yamasaki, T.; Otsuguro, K.-i.; Horiuchi, M.; Iijima, N.; Kimura, K.; Toda, C.
10.1101/2020.07.02.183780 — physiology — Posted on 2020-07-03
4529 Large genomic variants reveal unexplored intraspecific diversity in Brassica rapa genomes
Boutte, J.; Maillet, L.; Chaussepied, T.; Letort, S.; Aury, J.-M.; Belser, C.; Boideau, F.; Brunet, A.; Coriton, O.; Deniot, G.; Falentin, C.; Huteau, V.; Lode-Taburel, M.; Morice, J.; Trotoux, G.; Chevre, A.-M.; Rousseau-Gueutin, M.; Ferreira de Carvalho, J.
10.1101/2020.07.02.183640 — genomics — Posted on 2020-07-03
4530 Reintroduced native Populus nigra in restored floodplain reduces spread of exotic poplar species
Vanden Broeck, A.; Cox, K.; Van Braeckel, A.; Neyrinck, S.; De Regge, N.; Van Looy, K.
10.1101/2020.07.02.183699 — ecology — Posted on 2020-07-03
4533 Human hormone seasonality
Tendler, A.; Bar, A.; Mendelson Cohen, N.; Karin, O.; Korem Kohanim, Y.; Maimon, L.; Milo, T.; Raz, M.; Mayo, A.; Tanay, A.; Alon, U.
10.1101/2020.02.13.947366 — systems biology — Posted on 2020-07-03
4536 Alpha-1 antitrypsin inhibits SARS-CoV-2 infection
Wettstein, L.; Conzelmann, C.; Mueller, J. A.; Weil, T.; Gross, R.; Hirschenberger, M.; Seidel, A.; Klute, S.; Prelli-Bozzo, c.; Zech, F.; Preising, N.; Fois, G.; Lochbaum, R.; Knaff, P.; Mailaender, V.; Staendker, L.; Thal, D.; Schumann, C.; Stenger, S.; Sparrer, K.; Kleger, A.; Lochnit, G.; Kirchhoff, F.; Frick, M.; Muench, J.
10.1101/2020.07.02.183764 — microbiology — Posted on 2020-07-02
4537 A new long-read dog assembly uncovers thousands of exons and functional elements missing in the previous reference
Wang, C.; Wallerman, O.; Arendt, M.-L.; Sundstrom, E.; Karlsson, A.; Nordin, J.; Makelainen, S.; Pielberg, G. R.; Hanson, J.; Ohlsson, A.; Saellstrom, S.; Ronnberg, H.; Ljungvall, I.; Haggstrom, J.; Bergstrom, T. F.; Hedhammar, A.; Meadows, J. R. S.; Lindblad-Toh, K.
10.1101/2020.07.02.185108 — genomics — Posted on 2020-07-02
4538 Connectivity patterns of task-specific brain networks allow individual prediction of cognitive symptom dimension of schizophrenia and link to molecular architecture
Chen, J.; Mueller, V. I.; Dukart, J.; Hoffstaedter, F.; Baker, J. T.; Holmes, A. J.; Vatansever, D.; Nickl-Jockschat, T.; Liu, X.; Derntl, B.; Kogler, L.; Jardri, R.; Gruber, O.; Aleman, A.; Sommer, I. E.; Eickhoff, S. B.; Patil, K. R.
10.1101/2020.07.02.185124 — neuroscience — Posted on 2020-07-02
4539 The Bacillus Virulome in Endophthalmitis
Coburn, P. S.; Miller, F. C.; Enty, M. A.; Land, C.; LaGrow, A. L.; Mursalin, M. H.; Callegan, M. C.
10.1101/2020.07.02.184630 — microbiology — Posted on 2020-07-02
4540 LOK/SLK kinases and ERM proteins function together to regulate apical morphology and inhibit RhoA signaling
Zaman, R.; Lombardo, A. T.; Sauvanet, C.; Viswanatha, R.; Awad, V.; Bonomo, L. E.; McDermitt, D. J.; Bretscher, A. P.
10.1101/2020.07.02.185298 — cell biology — Posted on 2020-07-02
4541 High-resolution structures of malaria parasite actomyosin and actin filaments
Vahokoski, J.; Calder, L. J.; Lopez, A. J.; Molloy, J. E.; Rosenthal, P. B.; Kursula, I.
10.1101/2020.07.02.183871 — biophysics — Posted on 2020-07-02
4542 Binding of the SARS-CoV-2 Spike Protein to Glycans
Hao, W.; Ma, B.; Li, Z.; Wang, X.; Gao, X.; Li, Y.; Qin, B.; Shang, S.; Cui, S.; Tan, Z.
10.1101/2020.05.17.100537 — biochemistry — Posted on 2020-07-02
4543 Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike
Derking, R.; Allen, J. D.; Cottrell, C.; Sliepen, K.; Seabright, G. E.; Lee, W.-H.; Rantalainen, K.; Antanasijevic, A.; Copps, J.; Yasmeen, A.; van der Woude, P.; de Taeye, S. W.; van den Kerkhof, T. L. G. M.; Klasse, P. J.; Ozorowski, G.; van Gils, M. J.; Moore, J. P.; Ward, A.; Crispin, M.; Sanders, R. W.
10.1101/2020.07.02.184135 — biochemistry — Posted on 2020-07-02
4544 Urine metabolomics of rats with chronic atrophic gastritis
zu, g.; Zu, G.-X.; Sun, Q.-Q.; chen, j.; Liu, X.-J.; Sun, K.-Y.; Zhang, L.-K.; li, l.; Huang, H.-l.; Han, T.
10.1101/2020.07.02.184218 — molecular biology — Posted on 2020-07-02
4546 Neuronal non-CG methylation is an essential target for MeCP2 function
Tillotson, R.; Cholewa-Waclaw, J.; Chhatbar, K.; Connelly, J.; Kirschner, S. A.; Webb, S.; Koerner, M. V.; Selfridge, J.; Kelly, D.; De Sousa, D.; Brown, K.; Lyst, M. J.; Kriaucionis, S.; Bird, A. P.
10.1101/2020.07.02.184614 — genetics — Posted on 2020-07-02
4547 drICE restrains DIAP2-mediated inflammatory signalling and intestinal inflammation
Kietz, C.; Pollari, V.; Tuominen, I.-E.; Ribeiro, P. S.; Meier, P.; Meinander, A.
10.1101/2020.05.29.122978 — cell biology — Posted on 2020-07-02
4549 Resilience and evolvability of protein-protein interaction networks
Klein, B.; Holmer, L.; Smith, K. M.; Johnson, M. M.; Swain, A.; Stolp, L.; Teufel, A. I.; Kleppe, A.
10.1101/2020.07.02.184325 — systems biology — Posted on 2020-07-02
4550 3 versus 7 Tesla Magnetic Resonance Imaging for parcellations of subcortical brain structures
Alkemade, A.; Isaacs, B.; Mulder, M.; Groot, J.; Van Berendonk, N.; Lute, N.; Bazin, P.-L.; Forstmann, B.
10.1101/2020.07.02.184275 — neuroscience — Posted on 2020-07-02
4554 Potential anti-adipogenic activity of Calligonum comosum cuminaldehyde on mouse 3T3-preadipocytes
Mohammad, M. G.; El-Serafi, A.; Madkour, M. I.; Alhabshi, A.; Wadea, A.; AboJabal, R.; P, D. P.; Soliman, S. S. M.
10.1101/2020.07.02.184200 — physiology — Posted on 2020-07-02
4555 Effects of prophylactic and therapeutic antimicrobial uses in small-scale chicken flocks
Nguyen, V. C.; Bach, T. K.; Doan, H. P.; Nguyen, T. B. V.; Vo, B. H.; Thwaites, G.; CARRIQUE-MAS, J.; Choisy, M.
10.1101/2020.07.02.183715 — pharmacology and toxicology — Posted on 2020-07-02
4556 Effects of practice on a mechanical horse with an online feedback on performing a sitting postural coordination
BAILLET, H.; Leroy, D.; Verin, E.; Delpouve, C.; Boulanger, J.; Benguigui, N.; Komar, J.; Thouvarecq, R.
10.1101/2020.07.02.184234 — neuroscience — Posted on 2020-07-02
4557 Systematic comparison and automated validation of detailed models of hippocampal neurons
Saray, S.; Rössert, C. A.; Appukuttan, S.; Migliore, R.; Vitale, P.; Lupascu, C. A.; Bologna, L. L.; Van Geit, W.; Romani, A.; Davison, A. P.; Muller, E.; Freund, T. F.; Kali, S.
10.1101/2020.07.02.184333 — neuroscience — Posted on 2020-07-02
4558 Penicillium purpurogenum exerts antitumor effects and ameliorates inflammations in Erlich mice model
Teles, A. M.; Pontes, L. P. P.; Guimaraes, S. J. A.; Butarelli, A. L. d. A.; Silva, G. X.; do Nascimento, F. R. F.; Bezerra, G. F. d. B.; Moragas-Tellis, C. J.; da Costa, R. M. G.; da Silva, M. A. C. N.; Almeida-Souza, F.; Azevedo-Santos, A. P. S.; Nascimento, M. d. D. S. B.
10.1101/2020.07.02.184291 — microbiology — Posted on 2020-07-02
4560 Title: Acetylcholine regulates pulmonary inflammation and facilitates the transition from active immunity to tissue repair during respiratory viral infection
Horkowitz, A. P.; Schwartz, A. V.; Alvarez, C. A.; Herrera, E. B.; Thoman, M. L.; Chatfield, D. A.; Osborn, K. G.; Feuer, R.; George, U. Z.; Phillips, J. A.
10.1101/2020.07.02.184226 — immunology — Posted on 2020-07-02
4562 Long-read genome sequencing for the diagnosis of neurodevelopmental disorders
Hiatt, S. M.; Lawlor, J. M.; Handley, L. H.; Ramaker, R. C.; Rogers, B. B.; Partridge, E. C.; Boston, L. B.; Williams, M.; Jenkins, J.; Gray, D. E.; Bowling, K. M.; Bebin, E. M.; Grimwood, J.; Schmutz, J.; Cooper, G. M.
10.1101/2020.07.02.185447 — genomics — Posted on 2020-07-02
4563 Multi-ethnic transcriptome-wide association study of prostate cancer
Fiorica, P. N.; Schubert, R.; Morris, J. D.; Abdul Sami, M.; Wheeler, H. E.
10.1101/2020.07.02.184283 — genetics — Posted on 2020-07-02
4565 Molecular Logic of Cellular Diversification in the Mammalian Cerebral Cortex
Di Bella, D. J.; Habibi, E.; Yang, S.-M.; Stickels, R. R.; Brown, J.; Yadollahpour, P.; Chen, F.; Macosko, E. Z.; Regev, A.; Arlotta, P.
10.1101/2020.07.02.185439 — developmental biology — Posted on 2020-07-02
4566 Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis
Hofemeier, A. D.; Limon, T.; Muenker, T. M.; Wallmeyer, B.; Jurado, A.; Afshar, M. E.; Ebrahimi, M.; Gilbert, P. M.; Betz, T.
10.1101/2020.06.24.164988 — biophysics — Posted on 2020-07-02
4569 A commercial autogenous injection vaccine protects ballan wrasse (Labrus bergylta, Ascanius) against Aeromonas salmonicida vapA type V
Ramirez Paredez, G.; Verner-Jeffreys, D.; Papadopoulou, A.; Monaghan, S.; Smith, L.; Haydon, D.; Wallis, T.; Davie, A.; Adams, A.; Migaud, H.
10.1101/2020.07.02.183616 — pathology — Posted on 2020-07-02
4572 The development of attentional control mechanisms in multisensory environments
Turoman, N.; Tivadar, R. I.; Retsa, C.; Maillard, A. M.; Scerif, G.; Matusz, P. J.
10.1101/2020.06.23.166975 — neuroscience — Posted on 2020-07-02
4573 Metagenome-assembled genomes from Monte Cristo Cave (Diamantina, Brazil) reveal prokaryotic lineages as functional models for life on Mars
Bendia, A. G.; Callefo, F.; Araujo, M.; Sanchez, E.; Teixeira, V.; Vasconcelos, A.; Battilani, G.; Pellizari, V. H.; Rodrigues, F.; Galante, D.
10.1101/2020.07.02.185041 — microbiology — Posted on 2020-07-02
4576 Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization
kanfer, G.; Sarraf, S. A.; Maman, Y.; Baldwin, H.; Johnson, K. R.; Ward, M. E.; Kampmann, M.; Lippincott-Schwartz, J.; Youle, R. J.
10.1101/2020.07.02.184390 — cell biology — Posted on 2020-07-02
4578 A novel saline-soluble, rapidly-metabolized RyR1 inhibitor rescues volatile anesthesia-induced death and environmental heat stroke in a mouse model relevant to malignant hyperthermia
Yamazawa, T.; Kobayashi, T.; Kurebayashi, N.; Konishi, M.; Noguchi, S.; Inoue, T.; Inoue, Y. U.; Nishino, I.; Mori, S.; Iinuma, H.; Manaka, N.; Kagechika, H.; Uryas, A.; Adams, J.; Lopez, J. R.; Liu, X.; Allen, P. D.; Kakizawa, S.; Ikeda, K.; Lin, B.; Nunomura, K.; Nakagawa, S.; Sakurai, T.; Murayama, T.
10.1101/2020.07.02.185520 — pharmacology and toxicology — Posted on 2020-07-02
4580 Developmental, cellular, and biochemical basis of transparency in the glasswing butterfly Greta oto
Pomerantz, A. F.; Siddique, R. H.; Cash, E. I.; Kishi, Y.; Pinna, C.; Hammar, K.; Gomez, D.; Elias, M.; Patel, N. H.
10.1101/2020.07.02.183590 — developmental biology — Posted on 2020-07-02
4586 The transcriptional repressor Zfp125 modifies hepatic energy metabolism in response to fasting and insulin resistance
Fernandes, G. W.; Bocco, B. M. L. C.; Fonseca, T. d. L.; Salas-Lucia, F.; Nickel, O.; Russo, S. C.; Gereben, B.; Kettelhut, I. C.; Bianco, A. C.
10.1101/2020.07.02.185165 — physiology — Posted on 2020-07-02
4591 Modified HIF expression in CD8+ T cells increases anti-tumor efficacy
Velica, P.; Cunha, P. P.; Vojnovic, N.; Foskolou, I. P.; Bargiela, D.; Gojkovic, M.; Rundqvist, H.; Johnson, R. S.
10.1101/2020.06.18.159137 — immunology — Posted on 2020-07-02
4592 Development of a Synthetic Poxvirus-Based SARS-CoV-2 Vaccine
Chiuppesi, F.; Werner, M. S.; Contreras, H.; Nguyen, H. V.; Martinez, J.; Park, S.; Nguyen, J.; Kha, M.; Iniguez, A.; Zhou, Q.; Kaltcheva, T.; Levytskyy, R.; Ebelt, N. D.; Kang, T. H.; Wu, X.; Rogers, T.; Manuel, E. R.; Shostak, Y.; Diamond, D. J.; Wussow, F.
10.1101/2020.07.01.183236 — immunology — Posted on 2020-07-02
4593 Non-allelic homologous recombination of Alu and LINE-1 elements generates somatic complexity in human genomes.
Pascarella, G.; Hashimoto, K.; Busch, A.; Luginbuehl, J.; Parr, C.; Hon, C.-C.; Yip, W. H.; Kratz, A.; Bonetti, A.; Agostini, F.; Severin, J.; Murayama, S.; Gustincich, S.; Frith, M.; Carninci, P.
10.1101/2020.07.02.163816 — genomics — Posted on 2020-07-02
4596 Persistence as an optimal hedging strategy
Browning, A. P.; Sharp, J. A.; Mapder, T.; Baker, C. M.; Burrage, K.; Simpson, M. J.
10.1101/2019.12.19.883645 — systems biology — Posted on 2020-07-02
4597 TEARS: Spatial engineering of E. coli with addressable phase-separated RNAs
Guo, H.; Ryan, J. C.; Mallet, A.; Song, X.; Pabst, V.; Decrulle, A.; Lindner, A. B.
10.1101/2020.07.02.182527 — synthetic biology — Posted on 2020-07-02
4598 Shared and specific signatures of locomotor ataxia in mutant mice
Machado, A. S.; Marques, H. G.; Duarte, D. F.; Darmohray, D. M.; Carey, M. R.
10.1101/2020.01.21.914077 — neuroscience — Posted on 2020-07-02
4599 Genome scale epigenomic analysis of response to acute stress in the European sea bass (Dicentrarchus labrax, L.)
KRICK, M. V.; DESMARAIS, E.; SAMARAS, A.; GUERET, E.; DIMITROGLOU, A.; PAVLIDIS, M.; TSIGENOPOULOS, C. S.; GUINAND, B.
10.1101/2020.06.19.160812 — genomics — Posted on 2020-07-02
4601 Excess Centrosomes Disrupt Vascular Lumenization and Endothelial Cell Adherens Junctions
Buglak, D. B.; Kushner, E. J.; Marvin, A. P.; Davis, K. L.; Bautch, V. L.
10.1101/863787 — cell biology — Posted on 2020-07-02
4602 Correlation guided Network Integration (CoNI) reveals novel genetic regulators of hepatic metabolism
Klaus, V. S.; Schriever, S. C.; Peter, A.; Monroy-Kuhn, J. M.; Irmler, M.; Tokarz, J.; Prehn, C.; Kastenmueller, G.; Beckers, J.; Adamski, J.; Koenigsrainer, A.; Mueller, T. D.; Heni, M.; Tschoep, M. H.; Pfluger, P. T.; Lutter, D.
10.1101/2020.01.29.924944 — bioinformatics — Posted on 2020-07-02
4603 Cooperative molecular networks drive a mammalian cell state transition
Lackner, A.; Sehlke, R.; Garmhausen, M.; Stirparo, G. G.; Huth, M.; Titz-Teixeira, F.; van der Lelij, P.; Ramesmayer, J.; Thomas, H. F.; Ralser, M.; Santini, L.; Sarov, M.; Stewart, A. F.; Smith, A. G.; Beyer, A.; Leeb, M.
10.1101/2020.03.23.000109 — systems biology — Posted on 2020-07-02
4605 Malaria in Pregnancy Regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 Efflux Transporters in the Mouse Visceral Yolk Sac
Martinelli, L. M.; Fontes, K. N.; Reginatto, M. W.; Andrade, C. B.; Monteiro, V. R.; Gomes, H. R.; Silva-Filho, J. L.; Pinheiro, A. A.; Vago, A. R.; Almeida, F. R.; Bloise, F. F.; Matthews, S. G.; Ortiga-Carvalho, T. M.; Bloise, E.
10.1101/2020.06.27.175018 — pharmacology and toxicology — Posted on 2020-07-02
4606 Molecular mechanism of SARS-Cov-2 components caused ARDS in murine model
Gu, T.; Zhao, S.; Jin, G.; Song, M.; Zhi, Y.; Zhao, R.; Ma, F.; Zheng, Y.; Wang, K.; Liu, H.; Xin, M.; Han, W.; Li, X.; Dong, C. D.; Liu, K.; Dong, Z.
10.1101/2020.06.07.119032 — pathology — Posted on 2020-07-02
4607 Sailing in rough waters: examining volatility of fMRI noise
Leppanen, J.; Stone, H.; Lythgoe, D. J.; Williams, S.; Horvath, B.
10.1101/2020.06.19.161570 — neuroscience — Posted on 2020-07-02
4614 Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections
Benard, A.; Jacobsen, A.; Brunner, M.; Krautz, C.; Klosch, B.; Swierzy, I.; Naschberger, E.; Birkholz, T.; Castellanos, I.; Trufa, D.; Sirbu, H.; Vetter, M.; Kremer, A. E.; Hildner, K.; Hecker, A.; Edinger, F.; Tenbusch, M.; Richter, E.; Streeck, H.; Berger, M. M.; Brenner, T.; Weigand, M. A.; Swirski, F. K.; Schett, G.; Grutzmann, R.; Weber, G. F.
10.1101/2020.07.02.184093 — immunology — Posted on 2020-07-02
4615 Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri
Castaneda-Zegarra, S.; Zhang, Q.; Alirezaylavasani, A.; Fernandez-Berrocal, M.; Yao, R.; Oksenych, V.
10.1101/2020.03.04.976829 — immunology — Posted on 2020-07-02
4616 Association between neutralizing antibodies to SARS-CoV-2 and commercial serological assays
Tang, M. S.; Case, J. B.; Franks, C. E.; Chen, R. E.; Anderson, N. W.; Henderson, J. P.; Diamond, M. S.; Gronowski, A. M.; Farnsworth, C. W.
10.1101/2020.07.01.182220 — immunology — Posted on 2020-07-02
4617 TRIM67 Regulates Exocytic Mode and Neuronal Morphogenesis via SNAP47
Urbina, F. l.; Menon, S.; Edwards, R. J.; Goldfarb, D.; Major, M. B.; Brennwald, P. J.; Gupton, S. L.
10.1101/2020.02.01.930404 — cell biology — Posted on 2020-07-02
4621 Homozygote loss-of-function variants in the human COCH gene underlie hearing loss
Danial-Farran, N.; Chervinsky, E.; Nadar-Ponniah, P. T.; Cohen Barak, E.; Taiber, S.; Khayat, M.; Avraham, K. B.; Shalev, S. A.
10.1101/2020.06.29.178053 — genetics — Posted on 2020-07-02
4624 Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis, and Poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets
Mavian, C. N.; Ramirez-Mata, A. S.; Dollar, J. J.; Nolan, D. J.; White, K.; Rich, S. N.; Rife Magalis, B.; Cash, M. N.; Marini, S.; Prosperi, M.; Moraga Amador, D.; Riva, A.; Williams, K. C.; Salemi, M.
10.1101/2020.05.21.109140 — pathology — Posted on 2020-07-02
4626 Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish
Bono, L.; Naranjo, S.; Moreno-Marmol, T.; de la Cerda, B.; Polvillo, R.; Diaz-Corrales, F. J.; Bogdanovic, O.; Bovolenta, P.; Martinez-Morales, J.-R.
10.1101/2020.05.28.121038 — developmental biology — Posted on 2020-07-02
4630 Visual attention modulates the integration of goal-relevant evidence and not value
Sepulveda, P.; Usher, M.; Davies, N.; Benson, A.; Ortoleva, P.; De Martino, B.
10.1101/2020.04.14.031971 — neuroscience — Posted on 2020-07-02
4632 6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities
Swaim, C. D.; Perng, Y.-C.; Zhao, X.; Canadeo, L. A.; Harastani, H. H.; Darling, T. L.; Boon, A. C. M.; Lenschow, D. J.; Huibregtse, J. M.
10.1101/2020.07.01.183020 — molecular biology — Posted on 2020-07-02
4633 Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission
Sapoval, N.; Mahmoud, M.; Jochum, M. D.; Liu, Y.; Elworth, R. A. L.; Wang, Q.; Albin, D.; Ogilvie, H.; Lee, M. D.; Villapol, S.; Hernandez, K.; Maljkovic Berry, I.; Foox, J.; Beheshti, A.; Ternus, K.; Aagaard, K. M.; Posada, D.; Mason, C.; Sedlazeck, F. J.; Treangen, T. J.
10.1101/2020.07.02.184481 — genomics — Posted on 2020-07-02
4634 Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis
Alvira-de-Celis, S.; Watkins, D. W.; Troman, L.; Allen, W. J.; Lorriman, J.; Degliesposti, G.; Cohen, E. J.; Beeby, M. J.; Daum, B.; Gold, V. A. M.; Skehel, J. M.; Collinson, I.
10.1101/589077 — biochemistry — Posted on 2020-07-02
4635 Lack of support for Deuterostomia prompts reinterpretation of the first Bilateria.
Kapli, P.; Natsidis, P.; Leite, D. J.; Fursman, M.; Jeffrie, N.; Rahman, I. A.; Philippe, H.; Copley, R.; Telford, M. J.
10.1101/2020.07.01.182915 — evolutionary biology — Posted on 2020-07-02
4637 A new species of planarian flatworm from Mexico: Girardia guanajuatiensis
Duncan, E. M.; Nowotarski, S. H.; Guerrero-Hernandez, C.; Ross, E. J.; D'Orazio, J. A.; Clubes de Ciencia Mexico Workshop for Developmental Biology, ; McKinney, S. A.; Guo, L.; Sanchez Alvarado, A.
10.1101/2020.07.01.183442 — developmental biology — Posted on 2020-07-02
4641 STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters
Boudewijns, R.; Thibaut, H. J.; Kaptein, S. J. F.; Li, R.; Vergote, V.; Seldeslachts, L.; De Keyzer, C.; Bervoets, L.; Sharma, S.; Van Weyenbergh, J.; Liesenborghs, L.; Ma, J.; Jansen, S.; Van Looveren, D.; Vercruysse, T.; Jochmans, D.; Wang, X.; Martens, E.; Roose, K.; De Vlieger, D.; Schepens, B.; Van Buyten, T.; Jacobs, S.; Liu, Y.; Marti-Carreras, J.; Vanmechelen, B.; Wawina-Bokalanga, T.; Delang, L.; Rocha-Pereira, J.; Coelmont, L.; Chiu, W.; Leyssen, P.; Heylen, E.; Schols, D.; Wang, L.; Close, L.; Matthijnssens, J.; Van Ranst, M.; Compernolle, V.; Schramm, G.; Van Laere, K.; Saelens, X.
10.1101/2020.04.23.056838 — microbiology — Posted on 2020-07-02
4645 Surface-Based Connectivity Integration
Cole, M.; Murray, K. D.; St-Onge, E.; Risk, B.; Zhong, J.; Schifitto, G.; Descoteaux, M.; Zhang, Z.
10.1101/2020.07.01.183038 — neuroscience — Posted on 2020-07-02
4648 A multi-informatic description of neural differentiation in the Drosophila type-II neuroblast lineages
Michki, N. S.; Li, Y.; Sanjasaz, K.; Zhao, Y.; Shen, F. Y.; Walker, L. A.; Lee, C.-Y.; Cai, D.
10.1101/2020.07.02.184549 — neuroscience — Posted on 2020-07-02
4651 Docosahexaenoic acid (DHA), a nutritional supplement, modulates steroid insensitivity in asthma
Panda, L.; Gheware, A. P.; Jaiswal, A.; Saha, D.; Desiraju, B. K.; Rehman, R.; Ray, A.; Dutta, J.; Singh, S.; Yadav, M. K.; Sowpati, D. T.; Chattopadhyay, S.; SubbaRao, M. V.; Mahesh, P. A.; Prakash, Y. S.; Chowdhury, S.; Agrawal, A.; Ghosh, B.; Mabalirajan, U.
10.1101/2020.07.01.181354 — immunology — Posted on 2020-07-02
4654 Stereotypic Neutralizing VH Clonotypes Against SARS-CoV-2 RBD in COVID-19 Patients and the Healthy Population
Kim, S. I.; Noh, J.; Kim, S.; Choi, Y.; Yoo, D. K.; Lee, Y.; Lee, H.; Jung, J.; Kang, C. K.; Song, K.-H.; Choe, P. G.; Kim, H. B.; Kim, E. S.; Kim, N.-J.; Seong, M.-W.; Park, W. B.; Oh, M.-d.; Kwon, S.; Chung, J.
10.1101/2020.06.26.174557 — immunology — Posted on 2020-07-02
4655 Targeting the ubiquitin-proteasome system in a pancreatic cancer subtype with hyperactive MYC
Lankes, K.; Hassan, Z.; Doffo, M. J.; Schneeweis, C.; Lier, S.; Oellinger, R.; Rad, R.; Kraemer, O. H.; Keller, U.; Saur, D.; Reichert, M.; Schneider, G.; Wirth, M.
10.1101/2020.07.01.182162 — cancer biology — Posted on 2020-07-02
4659 TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6
Lehmkuhl, E. M.; Loganathan, S.; Alsop, E.; Blythe, A. D.; Kovalik, T.; Barrameda, D.; Kueth, C.; Eck, R. J.; Siddegowda, B. B.; Joardar, A.; Mortimore, N. P.; Bowser, R.; Van Keuren-Jensen, K.; Zarnescu, D. C.
10.1101/2020.07.01.182360 — neuroscience — Posted on 2020-07-02
4660 Transcription-dependent domain-scale 3D genome organization in dinoflagellates
Marinov, G. K.; Trevino, A. E.; Xiang, T.; Kundaje, A.; Grossman, A. R.; Greenleaf, W.
10.1101/2020.07.01.181685 — genomics — Posted on 2020-07-02
4663 Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction
Mayr, F.; Moeller, G.; Garscha, U.; Fischer, J.; Rodriguez Castano, P.; Inderbinen, S. G.; Temml, V.; Waltenberger, B.; Schwaiger, S.; Hartmann, R. W.; Gege, C.; Martens, S.; Odermatt, A.; Pandey, A. V.; Werz, O.; Adamski, J.; Stuppner, H.; Schuster, D.
10.1101/2020.07.01.181859 — bioinformatics — Posted on 2020-07-02
4670 Reverse transcription quantitative PCR to detect low density malaria infections
Christensen, P.; Nosten, F.; Bozdech, Z.; Watthanaworawit, W.; Renia, L.; Ling, C. L.
10.1101/2020.07.01.183491 — microbiology — Posted on 2020-07-02
4672 Additive and non-additive epigenetic signatures of hybridisation between fish species with different mating systems
Berbel-Filho, W. M.; Tatarenkov, A.; Pacheco, G.; Espirito-Santo, H.; Lira, M.; Garcia de Leaniz, C.; Avise, J. C.; Lima, S.; Rodriguez Lopez, C. M.; Consuegra, S.
10.1101/2020.07.01.182022 — evolutionary biology — Posted on 2020-07-02
4673 Interactomic affinity profiling by holdup assay: acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase
Jane, P.; Gogl, G.; Kostmann, C.; Bich, G.; Girault, V.; Caillet-Saguy, C.; Eberling, P.; Vincentelli, R.; Wolff, N.; Trave, G.; Nomine, Y.
10.1101/2020.07.01.181487 — biophysics — Posted on 2020-07-02
4676 A controlled thermoalgesic stimulation device to identify novel pain perception biomarkers
Nunez Rivero, M.; Camino, B.; Diez, I.; Erramuzpe, A.; Martinez Gutierrez, E.; Stramaglia, S.; Ortiz Alvarez-Cienfuegos, J.; Cortes, J.
10.1101/2020.07.01.177568 — bioengineering — Posted on 2020-07-02
4678 Protein kinase A catalytic-α and catalytic-β proteins have non-redundant functions
Raghuram, V.; Salhadar, K.; Limbutara, K.; Park, E.; Yang, C.-R.; Knepper, M.
10.1101/2020.07.01.182691 — systems biology — Posted on 2020-07-02
4681 HYPERGLYCEMIA-INDUCED MIR-467 DRIVES TUMOR INFLAMMATION AND GROWTH IN BREAST CANCER
Gajeton, J.; Krukovets, I.; Muppala, S.; Verbovetskiy, D.; Zhang, J.; Stenina-Adognravi, O.
10.1101/2020.07.01.182766 — cancer biology — Posted on 2020-07-02
4683 MetaFunPrimer: primer design for targeting genes observed in metagenomes
Liu, J.; Villanueva, P.; Choi, J.; Gunturu, S.; Ouyang, Y.; Tiemann, L.; Cole, J. R.; Lee, J.; Howe, A.
10.1101/2020.07.01.183509 — bioinformatics — Posted on 2020-07-02
4684 Milk losses and dynamics during perturbations in dairy cows differ with parity and lactation stage
Adriaens, I.; Van den brulle, I.; D'Anvers, L.; Statham, J.; Geerinckx, K.; De vliegher, S.; Piepers, S.; Aernouts, B.
10.1101/2020.07.01.182568 — bioengineering — Posted on 2020-07-02
4686 The Small GTPase OsRac1 forms two distinct immune receptor complexes containing the PRR OsCERK1 and the NLR Pit
Akamatsu:, A.; Fujiwara, M.; Hamada, S.; Wakabayashi, M.; Yao, A.; Wang, Q.; Kosami, K.-i.; Dang, T. T.; Kaneko-Kawano, T.; Shimamoto, K.; Kawano, Y.
10.1101/2020.07.01.183301 — plant biology — Posted on 2020-07-02
4687 Brain-wide electrical dynamics encode an appetitive socioemotional state
Mague, S. D.; Talbot, A.; Blount, C.; Duffney, L. J.; Walder-Christensen, K. K.; Adamson, E.; Bey, A. L.; Ndubuizu, N.; Thomas, G.; Dalton Hughes, D. N.; Sinha, S.; Fink, A. M.; Gallagher, N. M.; Fisher, R. L.; Jiang, Y.-h.; Carlson, D. E.; Dzirasa, K.
10.1101/2020.07.01.181347 — neuroscience — Posted on 2020-07-02
4688 All hands on deck: Large-scale (re)sculpting of cortical circuits in post-resection children
Maallo, A. M. S.; Granovetter, M. C.; Freud, E.; Kastner, S.; Pinsk, M. A.; Patterson, C.; Behrmann, M.
10.1101/2020.07.01.183400 — neuroscience — Posted on 2020-07-02
4691 A psychophysically tuned computational model of human primary visual cortex produces geometric optical illusions
Retsa, C.; Hernando Ariza, A.; Noordanus, N. W.; Ruffoni, L.; Murray, M. M.; Franceschiello, B.
10.1101/2020.07.01.182329 — neuroscience — Posted on 2020-07-02
4692 An Antibody to RGMa Promotes Regeneration of Cochlear Synapses after Noise Exposure
Nevoux, J.; Alexandru, M.; Bellocq, T.; Tanaka, L.; Hayashi, Y.; Watabe, T.; Lalou, H.; Tani, K.; Edge, A.
10.1101/2020.07.01.183269 — neuroscience — Posted on 2020-07-02
4693 Ontogeny of the VIP+ interneuron sensory-motor circuit prior to active whisking
Vagnoni, C.; Baruchin, L. J.; Ghezzi, F.; Ratti, S.; Molnar, Z.; Butt, S.
10.1101/2020.07.01.182238 — neuroscience — Posted on 2020-07-02
4694 Trk Agonist Drugs Rescue Noise-Induced Hidden Hearing Loss
Fernandez, K.; Watabe, T.; Tong, M.; Meng, X.; Tani, K.; Kujawa, S.; Edge, A.
10.1101/2020.07.01.182931 — neuroscience — Posted on 2020-07-02
4695 Loop Extrusion Mediates Physiological Locus Contraction for V(D)J Recombination
Dai, H.-Q.; Hu, H.; Lou, J.; Ye, A. Y.; Chapdelaine-Williams, A. M.; Kyritsis, N.; Zhang, Y.; Manfredonia, N.; Judson, R.; Chen, H.; Johnson, K.; Lin, S.; Ba, Z.; Conte, A.; Casellas, R.; Lee, C.-S.; Alt, F. W.
10.1101/2020.06.30.181222 — immunology — Posted on 2020-07-02
4698 Smoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits
Arveseth, C. D.; Happ, J. T.; Hedeen, D. S.; Zhu, J.-F.; Capener, J. L.; Shaw, D. K.; Deshpande, I.; Liang, J.; Xu, J.; Stubben, S. L.; Nelson, I. B.; Walker, M. F.; Krogan, N. J.; Grunwald, D. J.; Hüttenhain, R.; Manglik, A.; Myers, B. R.
10.1101/2020.07.01.183079 — biochemistry — Posted on 2020-07-02
4702 Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits
Orchard, P.; Manickam, N.; Varshney, A.; Rai, V.; Kaplan, J.; Lalancette, C.; Gallagher, K.; Burant, C. F.; Parker, S. C. J.
10.1101/2020.07.01.183004 — genomics — Posted on 2020-07-02
4703 Phenotypic variation in two widespread Caribbean corals, Porites astreoides and P. divaricata, between mangrove and lagoon habitats
Scavo Lord, K.; Barcala, A.; Aichelman, H. E.; Kriefall, N. G.; Brown, C.; Knasin, L.; Secor, R.; Tone, C.; Tsang, L.; Finnerty, J. R.
10.1101/2020.06.30.181172 — ecology — Posted on 2020-07-02
4707 RanDeL-seq: A high-throughput method to map viral cis- and trans-acting elements
Notton, T.; Glazier, J. J.; Saykally, V. R.; Thompson, C. E.; Weinberger, L.
10.1101/2020.07.01.183574 — synthetic biology — Posted on 2020-07-02
4711 S-nitrosoglutathione reductase deficiency causes aberrant placental S-nitrosylation and preeclampsia.
Kulandavelu, S.; Dulce, R. A.; Murray, C. I.; Bellio, M. A.; Fritsch, J.; Kanashiro-Takeuchi, R.; Arora, H.; Paulino, E.; Soetkamp, D.; Balkan, W.; Van Eyk, J. E.; Hare, J. M.
10.1101/2020.07.01.183012 — physiology — Posted on 2020-07-02
4712 Sleep deprivation triggers somatostatin neurons in prefrontal cortex to initiate nesting and sleep via the preoptic and lateral hypothalamus
Tossell, K.; Yu, X.; Anuncibay Soto, B.; Vicente, M.; Miracca, G.; Giannos, P.; Miao, A.; Hsieh, B.; Ma, Y.; Yustos, R.; Vyssotski, A. L.; Constandinou, T.; Franks, N. P.; Wisden, W.
10.1101/2020.07.01.179671 — neuroscience — Posted on 2020-07-02
4713 A chronic photocapacitor implant for noninvasive neurostimulation with deep red light
Silvera-Ejneby, M.; Jakesova, M.; Ferrero, J. J.; Migliaccio, L.; Zhao, Z.; Berggren, M.; Khodagholy, D.; Derek, V.; Gelinas, J.; Glowacki, E. D.
10.1101/2020.07.01.182113 — neuroscience — Posted on 2020-07-02
4714 Chronic activation of fear engrams induces extinction-like behavior in ethanol-exposed mice
Cincotta, C.; Murawski, N. J.; Grella, S. L.; McKissick, O.; Doucette, E.; Ramirez, S.
10.1101/2020.07.01.182782 — neuroscience — Posted on 2020-07-02
4715 High-performance brain-to-text communication via imagined handwriting
Willett, F. R.; Avansino, D. T.; Hochberg, L. R.; Henderson, J. M.; Shenoy, K. V.
10.1101/2020.07.01.183384 — neuroscience — Posted on 2020-07-02
4717 Desulfovibrio diazotrophica sp. nov., a sulphate reducing bacterium from the human gut capable of nitrogen fixation
Sayavedra, L.; Li, T.; Bueno Batista, M.; Seah, B. K. B.; Booth, C.; Zhai, Q.; Chen, W.; Narbad, A.
10.1101/2020.07.01.183566 — microbiology — Posted on 2020-07-02
4721 Molecular underpinnings and biogeochemical consequences of enhanced diatom growth in a warming Southern Ocean
Jabre, L.; Allen, A. E.; McCain, J. S. P.; McCrow, J. P.; Tenenbaum, N.; Spackeen, J. E.; Sipler, R. E.; Green, B. R.; Bronk, D. A.; Hutchins, D. A.; Bertrand, E. M.
10.1101/2020.07.01.177865 — ecology — Posted on 2020-07-02
4722 Species traits predict extinction risk across the Tree of Life
Chichorro, F.; Urbano, F.; Teixeira, D.; Väre, H.; Pinto, T.; Brummitt, N.; He, X.; Hochkirch, A.; Hyvönen, J.; Kaila, L.; Juslen, A.; Cardoso, P.
10.1101/2020.07.01.183053 — ecology — Posted on 2020-07-02
4724 Pericytes Directly Communicate with Emerging Endothelial Cells During Vasculogenesis
Payne, L. B.; Tewari, B.; Dunkenberger, L.; Bond, S.; Savelli, A.; Darden, J.; Zhao, H.; Powell, M.; Oestreich, K.; Sontheimer, H.; Dal-Pra, S.; Chappell, J. C.
10.1101/2020.07.01.180752 — developmental biology — Posted on 2020-07-02
4726 Profiling the Intratumoral Immune Landscapes of Primary and Syngeneic Kras-driven Sarcoma Mouse Models
Gutierrez, W. R.; Scherer, A.; McGivney, G. R.; Knepper-Adrian, V.; Laverty, E. A.; Roughton, G.; Dodd, R. D.
10.1101/2020.07.01.181263 — cancer biology — Posted on 2020-07-02
4728 Stealth fluorescence labeling for live microscopy imaging of mRNA delivery
Baladi, T.; Nilsson, J. R.; Gallud, A.; Celauro, E.; Gasse, C.; Levi-Acobas, F.; Sarac, I.; Hollenstein, M.; Dahlen, A.; Esbjörner, E. K.; Wilhelmsson, M.
10.1101/2020.07.01.172767 — biochemistry — Posted on 2020-07-02
4729 Comparative analysis of clonal evolution among patients with right-sided colon cancer, left-sided colon cancer and rectal cancer
Banerjee, S.; Zhang, X.; Kuang, S.; Wang, J.; Li, L.; Fan, G.; Luo, Y.; Sun, S.; Han, P.; Wu, Q.; Yang, S.; Ji, X.; Li, Y.; Deng, L.; Tian, X.; Wang, Z.; Zhang, Y.; Wu, K.; Zhu, S.; Bolund, L.; Yang, H.; Xu, X.; Liu, J.; Lu, Y.; Liu, X.
10.1101/2020.07.01.181586 — cancer biology — Posted on 2020-07-02
4730 Biofabrication of muscle fibers enhanced with plant viral nanoparticles using surface chaotic flows
Frias-Sanchez, A. I.; Quevedo-Moreno, D. A.; Samandari, M.; Tavares-Negrete, J. A.; Sanchez-Rodriguez, V. H.; Gonzalez-Gamboa, I.; Ponz, F.; Alvarez, M. M.; Trujillo-de Santiago, G.
10.1101/2020.06.30.181214 — bioengineering — Posted on 2020-07-02
4733 Selective Nanotherapeutic Targeting of the Neutrophil Subset Mediating Inflammatory Injury
Bachmaier, K.; Stuart, A.; Hong, Z.; Tsukasaki, Y.; Singh, A.; Chakraborty, S.; Mukhopadhyay, A.; Gao, X.; Maienschein-Cline, M.; Kanteti, P.; Rehman, R.; Malik, A. B.
10.1101/2020.06.30.180927 — immunology — Posted on 2020-07-02
4735 Important effect of the X chromosome in genomic evaluations of reproductive traits in beef cattle
Solar Diaz, I. D. P.; Camargo, G. M. F. d.; Cruz, V. A. R. d.; Hermisdorff, I. D. C.; Carvalho, C. V. D.; Albuquerque, L. G. d.; Costa, R. B.
10.1101/2020.06.30.178558 — genomics — Posted on 2020-07-02
4736 Genomic and TCR Repertoire Intratumor Heterogeneity of Small-cell Lung Cancer and its Impact on Survival
Chen, M.; Chen, R.; Jin, Y.; Li, J.; Zhang, J.; Fujimoto, J.; Lee, W.-C.; hu, x.; Hubert, S. M.; George, J.; Hu, X.; Chen, Y.; Behrens, C.; Chow, C.-W.; Pham, H. H. N.; Fukuoka, J.; Parra, E. R.; Gay, C. M.; Little, L. D.; Gumbs, C.; Song, X.; Diao, L.; Wang, Q.; Cardnell, R.; Zhang, J.; Wang, J.; Gibbons, D. L.; Heymach, J.; Lee, J. J.; William, W. N.; Glisson, B.; Wistuba, I.; Futreal, P. A.; Thomas, R. K.; Reuben, A.; Byers, L.; Zhang, J.
10.1101/2020.06.30.180844 — genomics — Posted on 2020-07-02
4737 Convergence in light transmission properties of transparent wing areas in clearwing mimetic butterflies
Pinna, C. S.; Vilbert, M.; Borenztajn, S.; Daney de Marcillac, W.; Piron-Prunier, F.; Pomerantz, A. F.; Patel, N. H.; Berthier, S.; Andraud, C.; Gomez, D.; Elias, M.
10.1101/2020.06.30.180612 — evolutionary biology — Posted on 2020-07-02
4739 Inkjet based 3D Printing of bespoke medical devices that resist bacterial biofilm formation
He, Y.; Begines, B.; Luckett, J.; Dubern, J.-F.; Hook, A.; Prina, E.; Rose, F. R.; Tuck, C.; Hague, R.; Irvine, D.; Williams, P.; Alexander, M. R.; Wildman, R. D.
10.1101/2020.06.30.180596 — bioengineering — Posted on 2020-07-02
4741 RNA degradation sculpts the maternal transcriptome during Drosophila oogenesis
Blatt, P.; Wong-Deyrup, S. W.; McCarthy, A.; Breznak, S.; Hurton, M. D.; Upadhyay, M.; Bennink, B.; Camacho, J.; Lee, M. T.; Rangan, P.
10.1101/2020.06.30.179986 — developmental biology — Posted on 2020-07-02
4745 Cis-regulatory evolution spotlights species differences in the adaptive potential of gene expression plasticity
He, F.; Steige, K. A.; Kovacova, V.; Goebel, U.; Bouzid, M.; Keightley, P. D.; Beyer, A.; de Meaux, J.
10.1101/2020.07.02.184036 — evolutionary biology — Posted on 2020-07-02
4752 Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart
Cahill, T. J.; Sun, X.; Ravaud, C.; Villa del Campo, C.; Klaourakis, K.; Lupu, I.-E.; Lord, A. M.; Browne, C.; Jacobsen, S. E. W.; Greaves, D. R.; Jackson, D. G.; Cowley, S. A.; James, W.; Choudhury, R. P.; Vieira, J. M.; Riley, P. R.
10.1101/2020.06.30.179952 — developmental biology — Posted on 2020-07-02
4753 Androgen Receptor promotes renal cell carcinoma (RCC) vasculogenic mimicry (VM) via altering TWIST1 nonsense-mediated decay through lncRNA-TANAR
Chang, C.; You, B.; Sun, Y.; Liu, Q.; Wang, K.; Fang, R.; Liu, B.; Chou, F.; Luo, J.; Wang, R.; Meng, J.; Huang, C.-P.; Yeh, S.; Xu, W.
10.1101/2020.06.30.180067 — cancer biology — Posted on 2020-07-02
4756 KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas
Heward, J. A.; Koniali, L.; D'Avola, A.; Close, K.; Yeomans, A.; Philpott, M.; Dunford, J.; Rahim, T.; Al Seraihi, A. F.; Wang, J.; Korfi, K.; Araf, S.; Iqbal, S.; Bewicke-Copley, F.; Kumar, E.; Barisic, D.; Calaminici, M.; Clear, A.; Gribben, J.; Johnson, P.; Neve, R.; Okosun, J.; Oppermann, U.; Melnick, A.; Packham, G.; Fitzgibbon, J.
10.1101/2020.06.30.177477 — cancer biology — Posted on 2020-07-02
4757 Spatial summation of pain increases logarithmically
Adamczyk, W. M.; Manthey, L.; Domeier, C.; Szikszay, T. M.; Luedtke, K.
10.1101/2020.06.30.179556 — physiology — Posted on 2020-07-02
4761 Consistent cross-modal identification of cortical neurons with coupled autoencoders
Gala, R.; Budzillo, A.; Baftizadeh, F.; Miller, J. A.; Gouwens, N. W.; Arkhipov, A.; Tasic, B.; Murphy, G.; Zeng, H.; Hawrylycz, M.; Sümbül, U.
10.1101/2020.06.30.181065 — neuroscience — Posted on 2020-07-02
4762 Lateral Hypothalamic GABAergic neurons encode and potentiate sucrose palatability
Garcia, A.; Coss, A.; Luis-Islas, J.; Puron-Sierra, L.; Luna, M.; Villavicencio, M.; Gutierrez, R.
10.1101/2020.06.30.180646 — neuroscience — Posted on 2020-07-02
4763 Sequential MAVS- and MyD88/TRIF-signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes
Ghita, L.; Breitkopf, V.; Mulenge, F.; Pavlou, A.; Gern, O. L.; Duran, V.; Prajeeth, C. K.; Kohls, M.; Jung, K.; Stangel, M.; Steffen, I.; Kalinke, U.
10.1101/2020.06.30.177485 — immunology — Posted on 2020-07-02
4764 Phenotypic analysis of an MLL-AF4 gene regulatory network reveals indirect CASP9 repression as a mode of inducing apoptosis resistance.
Harman, J. R.; Thorne, R.; Jamilly, M.; Tapia, M.; Crump, N. T.; Rice, S.; Beveridge, R.; Morrissey, E.; de Bruijn, M. F. T. R.; Roberts, I.; Roy, A.; Fulga, T. A.; Milne, T. A.
10.1101/2020.06.30.179796 — genomics — Posted on 2020-07-02
4768 USH2A is a Meissner corpuscle end-organ protein necessary for vibration sensing in mice and humans
Schwaller, F.; Begay, V.; Garcia, G.; Taberner, F.; Moshourab, R.; McDonald, B.; Docter, T.; Kuehnemund, J.; Ojeda-Alonso, J.; Paricio-Montesinos, R.; Lechner, S. G.; Poulet, J. F.; Millan, J.; Lewin, G. R.
10.1101/2020.07.01.180919 — neuroscience — Posted on 2020-07-02
4771 Resting-state functional connectivity predicts recovery from visually induced motion sickness
Miyazaki, J.; Yamamoto, H.; Ichimura, Y.; Yamashiro, H.; Murase, T.; Yamamoto, T.; Umeda, M.; Higuchi, T.
10.1101/2020.06.30.180786 — neuroscience — Posted on 2020-07-02
4775 Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle
Blocquiaux, S.; Ramaekers, M.; Van Thienen, R.; Nielens, H.; Delecluse, C.; De Bock, K.; Thomis, M.
10.1101/2020.06.30.179465 — genomics — Posted on 2020-07-02
4777 Measuring the iron content of dopaminergic neurons in substantia nigra with MRI relaxometry
Brammerloh, M.; Morawski, M.; Weigelt, I.; Reinert, T.; Lange, C.; Pelicon, P.; Vavpetic, P.; Jankuhn, S.; Jaeger, C.; Alkemade, A.; Balesar, R.; Pine, K.; Gavriilidis, F.; Trampel, R.; Reimer, E.; Arendt, T.; Weiskopf, N.; Kirilina, E.
10.1101/2020.07.01.170563 — neuroscience — Posted on 2020-07-02
4780 SUV39 SET domains mediate crosstalk of heterochromatic histone marks
Stirpe, A.; Guidotti, N.; Northall, S.; Hainard, A.; Vadas, O.; Fierz, B.; Schalch, T.; Kilic, S.
10.1101/2020.06.30.177071 — molecular biology — Posted on 2020-07-02
4784 The UPRmt Preserves Mitochondrial Import to Extend Lifespan
Xin, N.; Durieux, J.; Yang, C.; Wolff, S.; Kim, H.-E.; Dillin, A.
10.1101/2020.07.01.182980 — cell biology — Posted on 2020-07-02
4787 The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation
Eisemann, T.; Allen, F.; Lau, K.; Shimamura, G. R.; Jeffrey, P. D.; Hughson, F. M.
10.1101/2020.07.01.181321 — cell biology — Posted on 2020-07-02
4789 Organic dust induced mitochondrial dysfunction could be targeted via cGAS-STING or mitochondrial NOX-2 inhibition
Massey, N.; Shrestha, D.; Bhat, S. M.; Kondru, N.; Charli, A.; Karriker, L. A.; Kanthasamy, A.; Charavaryamath, C.
10.1101/2020.07.01.182535 — cell biology — Posted on 2020-07-02
4791 High-frequency stimulation of ventral CA1 neurons reduces amygdala activity and inhibits fear
Graham, J.; D'Ambra, A.; Jung, S. J.; Vishwakarma, N.; Venkatesh, R.; Parigi, A.; Antzoulatos, E.; Fioravante, D.; Wiltgen, B.
10.1101/2020.07.01.183210 — neuroscience — Posted on 2020-07-02
4792 Two neuronal peptides encoded from a single transcript regulate mitochondrial function in Drosophila
Bosch, J. A.; Ugur, B.; Pichardo-Casas, I.; Rabasco, J.; Escobedo, F.; Zuo, Z.; Brown, B.; Celniker, S.; Bellen, H. J.; Sinclair, D.; Perrimon, N.
10.1101/2020.07.01.182485 — genomics — Posted on 2020-07-02
4794 Size-dependent protein segregation creates a spatial switch for Notch and APP signaling
Kwak, M.; Southard, K. M.; Kim, N. H.; Gopalappa, R.; Kim, W. R.; An, M.; Lee, H. J.; Farlow, J.; Georgakopoulos, A.; Robakis, N. K.; Seo, D.; Kim, H. B.; Kim, Y. H.; Cheon, J.; Gartner, Z. J.; Jun, Y.-w.
10.1101/2020.06.28.176560 — cell biology — Posted on 2020-07-02
4795 Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and correlation to tissue damage
Deinhardt-Emmer, S.; Wittschieber, D.; Sanft, J.; Kleemann, S.; Elschner, S.; Haupt, K. F.; Vau, V.; Häring, C.; Rödel, J.; Henke, A.; Ehrhardt, C.; Bauer, M.; Philipp, M.; Gassler, N.; Nietzsche, S.; Löffler, B.; Mall, G.
10.1101/2020.07.01.182550 — immunology — Posted on 2020-07-02
4796 Human adipocyte differentiation and composition of disease relevant lipids are regulated by miR-221-3p
Ahonen, M. A.; Asghar, M. Y.; Parviainen, S. J.; Liebisch, G.; Höring, M.; Leidenius, M.; Fischer-Posovszky, P.; Wabitsch, M.; Mikkola, T. S.; Törnquist, K.; Savolainen-Peltonen, H.; Haridas, P. A. N.; Olkkonen, V. M.
10.1101/2020.06.30.180083 — cell biology — Posted on 2020-07-02
4808 Isomerization of antimalarial drug WR99210 explains its inactivity in a commercial stock
Remcho, T. P.; Guggilapu, S. D.; Cruz, P.; Nardone, G. A.; Heffernan, G.; O'Conner, R.; Bewley, C. A.; Wellems, T.; Lane, K. D.
10.1101/2020.07.01.182402 — biochemistry — Posted on 2020-07-01
4809 Detection of complex genetic architecture using two-locus population differentiation: modeling epistasis
Huang, M.; Graham, B.; Zhang, G.; Bartlett, J.; Moore, J.; Muglia, L.; Williams, S. M.
10.1101/2020.07.01.182840 — genetics — Posted on 2020-07-01
4814 Phosphoregulation of HORMA domain protein HIM-3 promotes asymmetric synaptonemal complex disassembly in meiotic prophase in C. elegans
Sato-Carlton, A.; Nakamura-Tabuchi, C.; Li, X.; Boog, H.; Lehmer, M. K.; Rosenberg, S. C.; Barroso, C.; Martinez-Perez, E.; Corbett, K. D.; Carlton, P. M.
10.1101/2020.07.01.182063 — cell biology — Posted on 2020-07-01
4817 Opto-E-Dura: a Soft, Stretchable ECoG Array for Multimodal, Multi-scale Neuroscience
Renz, A.; Lee, J.; Tybrandt, K.; Brzezinski, M.; Lorenzo, D. A.; Cerra Cheraka, M.; Lee, J.; Helmchen, F.; Voros, J.; Lewis, C. M.
10.1101/2020.06.10.139493 — neuroscience — Posted on 2020-07-01
4818 Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimers mouse model
Stojakovic, A.; Trushin, S.; Sheu, A.; Khalili, L.; Chang, S.-Y.; Li, X.; Christensen, T.; Salisbury, J. L.; Geroux, R. E.; Gateno, B.; Flannery, P. J.; Dehankar, M.; Funk, C. C.; Wilkins, J.; Stepanova, A.; OHagan, T.; Galkin, A.; Nesbitt, J.; Zhu, X.; Tripathi, U.; Macura, S.; Tchkonia, T.; Pirtskhalava, T.; Kirkland, J. L.; Kudgus, R. A.; Schoon, R. A.; Reid, J. M.; Yamazaki, Y.; Kanekiyo, T.; Zhang, S.; Nemutlu, E.; Dzeja, P.; Jaspersen, A.; Kwon, C. Y. I.; Lee, M. K.; Trushina, E.
10.1101/2020.07.01.182428 — neuroscience — Posted on 2020-07-01
4819 A functional overlap between actively transcribed genes and chromatin boundary elements
Harrold, C. L.; Gosden, M. E.; Hanssen, L. L.; Stolper, R. J.; Downes, D. J.; Telenius, J. M.; Biggs, D.; Preece, C.; Alghadban, S.; Sharpe, J. A.; Davies, B.; Sloane-Stanley, J. A.; Kassouf, M. T.; Hughes, J. R.; Higgs, D. R.
10.1101/2020.07.01.182089 — genomics — Posted on 2020-07-01
4824 Males deploy multifaceted strategies and hijack longevity pathways to induce premature demise of the opposite sex
Booth, L. N.; Shi, C.; Tantilert, C.; Yeo, R. W.; Hebestreit, K.; Hollenhorst, C. N.; Murphy, C. T.; Brunet, A.
10.1101/2020.06.30.181008 — genetics — Posted on 2020-07-01
4830 Revival of light-evoked neuronal signals in the post-mortem mouse and human retina
Abbas, F.; Becker, S.; Jones, B. W.; Mure, L. S.; Panda, S.; Hanneken, A.; Vinberg, F.
10.1101/2020.06.30.180497 — neuroscience — Posted on 2020-07-01
4831 eEF3 promotes late stages of tRNA translocation on the ribosome
Ranjan, N.; Pochopien, A. A.; Wu, C. C.-C.; Beckert, B.; Blanchet, S.; Green, R.; Rodnina, M. V.; Wilson, D. N.
10.1101/2020.07.01.182105 — molecular biology — Posted on 2020-07-01
4832 The gut mycobiome of healthy mice is shaped by the environment and shapes metabolic outcomes in response to diet
Mims, T. S.; Al Abdullah, Q.; Stewart, J. D.; Watts, S. P.; White, C. T.; Rousselle, T. V.; Bajwa, A.; Han, J. C.; Willis, K. A.; Pierre, J. F.
10.1101/2020.06.25.158287 — microbiology — Posted on 2020-07-01
4833 Homozygote loss-of-function variants in the human COCH gene underlie hearing loss
Danial-Faran, N.; Chervinsky, E.; Nadar-Ponniah, P. T.; Cohen Barak, E.; Taiber, S.; Khayat, M.; Avraham, K. B.; Shalev, S. A.
10.1101/2020.06.29.178053 — genetics — Posted on 2020-07-01
4836 Female rat sexual behavior is unaffected by perinatal fluoxetine exposure
Hegstad, J.; Huijgens, P. T.; Houwing, D. J.; Olivier, J. D.; Heijkoop, R.; Snoeren, E.
10.1101/2020.05.29.122945 — animal behavior and cognition — Posted on 2020-07-01
4845 Dynamics of bacterial cell division: Z ring condensation is essential for cytokinesis
Squyres, G. R.; Holmes, M. J.; Barger, S. R.; Pennycook, B. R.; Ryan, J.; Yan, V. T.; Garner, E. C.
10.1101/2020.06.30.180737 — microbiology — Posted on 2020-07-01
4846 Complete vertebrate mitogenomes reveal widespread gene duplications and repeats
Formenti, G.; Rhie, A.; Balacco, J.; Haase, B.; Mountcastle, J.; Fedrigo, O.; Brown, S.; Capodiferro, M.; Al-Ajli, F. O.; Ambrosini, R.; Houde, P.; Koren, S.; Oliver, K.; Smith, M.; Skelton, J.; Betteridge, E.; Dolucan, J.; Corton, C.; Bista, I.; Torrance, J.; Tracey, A.; Wood, J.; Uliano-Silva, M.; Howe, K.; McCarthy, S.; Winkler, S.; Kwak, W.; Korlach, J.; Fungtammasan, A.; Fordham, D.; Costa, V.; Mayes, S.; Chiara, M.; Horner, D. S.; Myers, E. W.; Durbin, R.; Achilli, A.; Braun, E. L.; Phillippy, A. M.; Jarvis, E. D.; The Vertebrate Genomes Project Consortium,
10.1101/2020.06.30.177956 — genomics — Posted on 2020-07-01
4847 Negative screening for 12 rare LRRK2 pathogenic variants in a cohort of Nigerians with Parkinson disease
Rizig, M.; Ojo, O. O.; Athanasiou-Fragkouli, A.; Agabi, O. P.; Oshinaike, O. O.; Houlden, H.; Okubadejo, N. U.
10.1101/2020.06.30.179739 — genetics — Posted on 2020-07-01
4849 A scallop theorem for cells moving in 3D.
Godeau, A. L.; Leoni, M.; Comelles, J.; Delanoe-Ayari, H.; Ott, A.; Harlepp, S.; Sens, P.; Riveline, D.
10.1101/2020.05.07.081984 — biophysics — Posted on 2020-07-01
4850 Task specialization and its effects on research careers
Robinson-Garcia, N.; Costas, R.; Sugimoto, C. R.; Lariviere, V.; Nane, G. F.
10.1101/2020.07.01.181669 — scientific communication and education — Posted on 2020-07-01
4851 Evaluating aerosol and splatter following dental procedures: addressing new challenges for oral healthcare and rehabilitation
Allison, J.; Currie, C.; Edwards, D.; Bowes, C.; Coulter, J.; Pickering, K.; Kozhevnikova, E.; Durham, J.; Nile, C.; Jakubovics, N.; Rostami, N.; Holliday, R.
10.1101/2020.06.25.154401 — microbiology — Posted on 2020-07-01
4855 sPLINK: A Federated, Privacy-Preserving Tool as a Robust Alternative to Meta-Analysis in Genome-Wide Association Studies
Nasirigerdeh, R.; Torkzadehmahani, R.; Matschinske, J.; Frisch, T.; List, M.; Späth, J.; Weiss, S.; Völker, U.; Heider, D.; Wenke, N. K.; Kacprowski, T.; Baumbach, J.
10.1101/2020.06.05.136382 — bioinformatics — Posted on 2020-07-01
4858 Catalytically Enhanced Cas9 through Directed Protein Evolution
Hand, T. H.; Roth, M. O.; Smith, C. L.; Shiel, E.; Klein, K.; Gilbert, D. M.; Li, H.
10.1101/2020.07.01.183194 — synthetic biology — Posted on 2020-07-01
4859 Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney
Wang, X. X.; Myakala, K.; Libby, A. E.; Ranjit, S.; Takahashi, S.; Jones, B. A.; Bhasin, K.; Qi, Y.; Krausz, K.; Zerfas, P.; Panov, J.; velenosi, t. J.; patel, d. P.; Daneshpajouhnejad, P.; Titievsky, A.; Sharov, V.; Ostretsov, B.; Billon, C.; Kopp, J. B.; Rosenberg, A. Z.; Gonzalez, F. J.; Guha, U.; Brodsky, L.; Burris, T.; Levi, M.
10.1101/755801 — pathology — Posted on 2020-07-01
4863 Dopa decarboxylase is a genetic hub of parental control over offspring behavior
Bonthuis, P. J.; Steinwand, S.; Huang, W.-C.; Horndli, C. N. S.; Emery, J.; Kravitz, S.; Ferris, E.; Gregg, C.
10.1101/2020.06.23.168195 — neuroscience — Posted on 2020-07-01
4864 FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
Whitley, K. D.; Jukes, C.; Tregidgo, N.; Karinou, E.; Almada, P.; Henriques, R. D.; Dekker, C.; Holden, S.
10.1101/2020.07.01.182006 — microbiology — Posted on 2020-07-01
4867 Potential role of Mercury pollutants in the success of Methicillin-Resistant Staphylococcus aureus USA300 in Latin America
Gustave, C.-A.; Rasigade, J.-P.; Martins Simoes, P.; Couzon, F.; Bourg, C.; Tristan, A.; Laurent, F.; Wirth, T.; Vandenesch, F.
10.1101/2020.07.01.150961 — microbiology — Posted on 2020-07-01
4869 Genetic architecture of host proteins interacting with SARS-CoV-2
Pietzner, M.; Wheeler, E.; Carrasco-Zanini, J.; Raffler, J.; Kerrison, N. D.; Oerton, E.; Auyeung, V. P. W.; Luan, J.; Finan, C.; Casas, J. P.; Ostroff, R.; Williams, S. A.; Kastenmüller, G.; Ralser, M.; Gamazon, E. G.; Wareham, N. J.; Hingorani, A. D.; Langenberg, C.
10.1101/2020.07.01.182709 — genomics — Posted on 2020-07-01
4871 Inter-determination of blood metabolite levels and gut microbiome supported by Mendelian randomization
Liu, X.; Tong, X.; Zou, Y.; Lin, X.; Zhao, H.; Tian, L.; Jie, Z.; Wang, Q.; Zhang, Z.; Lu, H.; Xiao, L.; Qiu, X.; Zi, J.; Wang, R.; Xu, X.; Yang, H.; Wang, J.; Zong, Y.; Liu, W.; Kristiansen, K.; Hou, Y.; Zhu, S.; Jia, H.; Zhang, T.
10.1101/2020.06.30.181438 — genetics — Posted on 2020-07-01
4875 Iodine staining as a useful probe for distinguishing amyloid fibril polymorphs
Hiramatsu, T.; Yamamoto, N.; Ha, S.; Masuda, Y.; Yasuda, M.; Ishigaki, M.; Yuzu, K.; Ozaki, Y.; Chatani, E.
10.1101/2020.03.21.001214 — biochemistry — Posted on 2020-07-01
4877 Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Malignant Mesothelioma
Sementino, E.; Kadariya, Y.; Cheung, M.; Menges, C. W.; Tan, Y.; Kukuyan, A.-M.; Shrestha, U.; Karchugina, S.; Cai, K. Q.; Peri, S.; Duncan, J. S.; Chernoff, J.; Testa, J. R.
10.1101/2020.06.30.181453 — cancer biology — Posted on 2020-07-01
4878 Genetic analysis of SARS-CoV-2 strains collected from North Africa: viral origins and mutational spectrum
Laamarti, M.; Kartti, S.; Alouane, T.; Laamarti, R.; Allam, L.; Ouadghiri, M.; Chemao-Elfihri, M. W.; Smyej, I.; Rahoui, J.; Benrahma, H.; Diawara, I.; Essabbar, A.; Boumajdi, N.; Bendani, H.; Bouricha, E. M.; Aanniz, T.; El Attar, J.; El Hafidi, N.; El Jaoudi, R.; Sbabou, L.; Nejjari, C.; Amzazi, S.; Mentag, R.; Belyamani, L.; Ibrahimi, A.
10.1101/2020.06.30.181123 — genomics — Posted on 2020-07-01
4879 Genome-scale CRISPR screening for modifiers of cellular LDL uptake
Emmer, B.; Sherman, E. J.; Lascuna, P. J.; Graham, S. E.; Willer, C. J.; Ginsburg, D.
10.1101/2020.07.01.182246 — genomics — Posted on 2020-07-01
4884 periscope: sub-genomic RNA identification in SARS-CoV-2 ARTIC Network Nanopore Sequencing Data
Parker, M. D.; Lindsey, B. B.; Leary, S.; Gaudieri, S.; Chopra, A.; Wyles, M.; Angyal, A.; Green, L. R.; Parsons, P.; Tucker, R. M.; Brown, R.; Groves, D.; Johnson, K.; Carrilero, L.; Heffer, J.; Partridge, D.; Evans, C.; Razza, M.; Keeley, A. J.; Smith, N.; Wang, D.; Mallal, S.; de Silva, T. I.
10.1101/2020.07.01.181867 — bioinformatics — Posted on 2020-07-01
4888 Early-life stress facilitates the development of Alzheimer's disease pathology via angiopathy
Tanaka, T.; Hirai, S.; Hosokawa, M.; Saito, T.; Sakuma, H.; Saido, T.; Hasegawa, M.; Okado, H.
10.1101/2020.04.27.062729 — neuroscience — Posted on 2020-07-01
4889 Saliva sampling is an excellent option to increase the number of SARS CoV2 diagnostic tests in settings with supply shortages
Moreno-Contreras, J.; Espinoza, M. A.; Sandoval-Jaime, C.; Cantu-Cuevas, M. A.; Baron-Olivares, H.; Ortiz-Orozco, O.; Munoz-Rangel, A. V.; Hernandez-de la Cuz, M.; Eroza-Osorio, C. M.; Arias, C. F.; Lopez, S.
10.1101/2020.06.24.170324 — microbiology — Posted on 2020-07-01
4891 RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells
Subramanian, A.; Vernon, K.; Slyper, M.; Waldman, J.; Luecken, M. D.; Gosik, K.; Dubinsky, D.; Cuoco, M. S.; Keller, K.; Purnell, J.; Nguyen, L.; Dionne, D.; Rozenblatt-Rosen, O.; Weins, A.; Human Cell Atlas Lung Biological Network, ; Regev, A.; Greka, A.
10.1101/2020.06.23.167098 — genomics — Posted on 2020-07-01
4892 FGF signaling in development beyond canonical pathways
Ray, A. T.; Mazot, P.; Brewer, J. R.; Catela, C.; Dinsmore, C. J.; Soriano, P.
10.1101/2020.05.13.093252 — developmental biology — Posted on 2020-07-01
4898 The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases
Mäkinen, J. J.; Shin, Y.; Vieras, E.; Virta, P.; Metsä-Ketelä, M.; Murakami, K. S.; Belogurov, G. A.
10.1101/2020.06.30.179606 — biochemistry — Posted on 2020-07-01
4907 Functional impact and regulation of global alternative splicing patterns in heart development and disease
Marti-Gomez, C.; Larrasa-Alonso, J.; Lopez-Olaneta, M.; Villalba-Orero, M.; Garcia-Pavia, P.; Sanchez-Cabo, F.; Lara-Pezzi, E.
10.1101/2020.06.30.171983 — bioinformatics — Posted on 2020-07-01
4908 Streamlining Data-Intensive Biology With Workflow Systems
Reiter, T.; Brooks, P. T.; Irber, L.; Joslin, S. E. K.; Reid, C. M.; Scott, C.; Brown, C. T.; Pierce, N. T.
10.1101/2020.06.30.178673 — bioinformatics — Posted on 2020-07-01
4909 Scale-free structure of cancer networks and their vulnerability to hub-directed combination therapy
Chen, A. X.; Zopf, C. J.; Mettetal, J.; Shyu, W. C.; Bolen, J.; Chakravarty, A.; Palani, S.
10.1101/2020.07.01.159657 — systems biology — Posted on 2020-07-01
4910 Direct Quantification of in vivo Mutagenesis Using Duplex Sequencing
Valentine, C. C.; Young, R. R.; Fielden, M. R.; Kulkarni, R.; Williams, L. N.; Li, T.; Minocherhomji, S.; Salk, J. J.
10.1101/2020.06.28.176685 — genomics — Posted on 2020-07-01
4912 A secreted NlpC/P60 endopeptidase from Photobacterium damselae subsp. piscicida cleaves the peptidoglycan of potentially competing bacteria
Lisboa, J.; Pereira, C.; Rifflet, A.; Ayala, J. A.; Terceti, M. S.; Barca, A. V.; Rodrigues, I.; Barbosa Pereira, P. J.; Osorio, C. R.; Garcia-del Portillo, F.; Gomperts Boneca, I.; do Vale, A.; dos Santos, N. M. S.
10.1101/2020.06.30.181511 — microbiology — Posted on 2020-07-01
4913 Recent evolutionary history of tigers highlights contrasting roles of genetic drift and selection
Armstrong, E.; Khan, A.; Taylor, R. W.; Gouy, A.; Greenbaum, G.; Thiery, A.; Kang, J. T.; Redondo, S. A.; Prost, S.; Barsh, G.; Kaelin, C.; Phalke, S.; Chugani, A.; Gilbert, M.; Miquelle, D.; Zachariah, A.; Borthakur, U.; Reddy, A.; Louis, E.; Ryder, O.; Jhala, Y.; Petrov, D.; Excoffier, L.; Hadly, E.; Ramakrishnan, U.
10.1101/696146 — genomics — Posted on 2020-07-01
4916 An approach for normalization and quality control for NanoString RNA expression data
Bhattacharya, A.; Hamilton, A. M.; Furberg, H.; Pietzak, E.; Purdue, M. P.; Troester, M. A.; Hoadley, K. A.; Love, M. I.
10.1101/2020.04.08.032490 — genomics — Posted on 2020-07-01
4919 Identification of a long non-coding RNA regulator of liver carcinoma cell survival
Rybakova, Y.; Gonzalez, J.; Bogorad, R.; Chauhan, V.; Dong, Y.; Whittaker, C.; Koteliansky, V.; Anderson, D.
10.1101/2020.07.01.181693 — cancer biology — Posted on 2020-07-01
4920 Next generation of anti-PD-L1 Atezolizumab with better anti-tumor efficacy in vivo
Li, M.; Zhao, R.; Chen, J.; Tian, W.; Xia, C.; Liu, X.; Li, Y.; Yan, Y.; Li, S.; Sun, H.; Shen, T.; Ren, W.; Sun, L.
10.1101/2020.06.30.166207 — bioengineering — Posted on 2020-07-01
4923 SALL4 controls cell fate in response to DNA base composition
Pantier, R.; Chhatbar, K.; Quante, T.; Skourti-Stathaki, K.; Cholewa-Waclaw, J.; Alston, G.; Alexander-Howden, B.; Lee, H. Y.; Cook, A.; Spruijt, C.; Vermeulen, M.; Selfridge, J.; Bird, A.
10.1101/2020.06.30.179481 — genomics — Posted on 2020-07-01
4924 Epithelial layer unjamming shifts energy metabolism toward glycolysis
DeCamp, S. J.; Tsuda, V. M. K.; Ferruzzi, J.; Koehler, S. A.; Roblyer, D.; Giblin, J. T.; Zaman, M. H.; Ogassavara, N. C.; Mitchel, J. A.; Butler, J. P.; Fredberg, J. J.
10.1101/2020.06.30.180000 — biophysics — Posted on 2020-07-01
4925 Proteus software for physics-based protein design
Mignon, D.; Druart, K.; Opuu, V.; Polydorides, S.; Villa, F.; Gaillard, T.; Michael, E.; Archontis, G.; Simonson, T.
10.1101/2020.06.30.179549 — biophysics — Posted on 2020-07-01
4926 Potassium starvation induces autophagy in yeast
Rangarajan, N.; Kapoor, I.; Li, S.; Drossopoulos, P.; White, K. K.; Madden, V. J.; Dohlman, H. G.
10.1101/2020.06.30.179085 — biochemistry — Posted on 2020-07-01
4927 Cryo-EM structure of enteric adenovirus HAdV-F41 highlights structural divergence among human adenoviruses
Perez-Illana, M.; Martinez, M.; Condezo, G. N.; Hernando-Perez, M.; Mangroo, C.; Brown, M.; Marabini, R.; San Martin, C.
10.1101/2020.07.01.177519 — microbiology — Posted on 2020-07-01
4928 Mechanism and effects of the skeletal muscle Nav1.4 inhibition by cannabidiol
Ghovanloo, M.-R.; Choudhury, K.; Bandaru, T. S.; Fouda, M. A.; Rayani, K.; Rusinova, R.; Phaterpekar, T.; Nelkenbrecher, K.; Watkins, A. R.; Poburko, D.; Thewalt, J.; Andersen, O. S.; Delemotte, L.; Goodchild, S. J.; Ruben, P.
10.1101/2020.06.30.180943 — biophysics — Posted on 2020-07-01
4929 Receptor-independent membrane mediated pathways of serotonin action
Dey, S.; Surendran, D.; Enberg, O.; Gupta, A.; Fanibunda, S. E.; Das, A.; Maity, B. K.; Dey, A.; Kallianpur, M.; Scheidt, H.; Walker, G.; Vaidya, V. A.; Huster, D.; Maiti, S.
10.1101/2020.07.01.177451 — biophysics — Posted on 2020-07-01
4936 Soft ticks perform evaporative cooling during blood-feeding
Lazzari, C. R.; Fauquet, A.; Lahondere, C.; Araujo, R.; Pereira, M. H.
10.1101/2020.06.30.180968 — zoology — Posted on 2020-07-01
4937 Importin α2 associates with chromatin via a novel DNA binding domain
Jibiki, K.; Kodama, T.; Suenaga, A.; Kawase, Y.; Shibazaki, N.; Nomoto, S.; Nagasawa, S.; Nagashima, M.; Shimodan, S.; Kikuchi, R.; Saitoh, N.; Yoneda, Y.; Akagi, K.-i.; Yasuhara, N.
10.1101/2020.05.04.075580 — molecular biology — Posted on 2020-07-01
4948 The essential role of feedback processing for figure-ground perception in mice
Kirchberger, L.; Mukherjee, S.; Schnabel, U. H.; van Beest, E.; Barsegyan, A.; Levelt, C. N.; Heimel, J. A.; Lorteije, J. A. M.; van der Togt, C.; Self, M. W.; Roelfsema, P. R.
10.1101/456459 — neuroscience — Posted on 2020-07-01
4949 Pervasively thinner neocortex as a transdiagnostic feature of general psychopathology
Romer, A. L.; Elliott, M. L.; Knodt, A. R.; Sison, M. L.; Ireland, D.; Houts, R.; Ramrakha, S.; Poulton, R.; Keenan, R.; Melzer, T. R.; Moffitt, T. E.; Caspi, A.; Hariri, A. R.
10.1101/788232 — neuroscience — Posted on 2020-07-01
4952 Sub-lethal insecticide exposure affects host biting efficiency of Kdr-resistant Anopheles gambiae
Diop, M. M.; Chandre, F.; Rossignol, M.; Porciani, A.; Chateau, M.; Moiroux, N.; Pennetier, C.
10.1101/653980 — animal behavior and cognition — Posted on 2020-07-01
4959 A simple, safe and sensitive method for SARS-CoV-2 inactivation and RNA extraction for RT-qPCR
Kalnina, L.; Mateu-Regue, A.; Oerum, S.; Hald, A.; Gerstoft, J.; Oerum, H.; Cilius Nielsen, F.; Iversen, A. K. N.
10.1101/2020.06.29.179176 — microbiology — Posted on 2020-07-01
4960 Multicenter comparison of the Cobas 6800 system with the RealStar RT-PCR kit for the detection of SARS-CoV-2
Chaix, M.-L.; Wirden, M.; Feghoul, L.; Bertine, M.; Nere, M.-L.; Le Hingrat, Q.; Abdi, B.; Boutolleau, D.; Ferre, V. M.; Jary, A.; Delaugerre, C.; Marcelin, A.-G.; Descamps, D.; LeGoff, J.; Visseaux, B.
10.1101/2020.06.29.179184 — microbiology — Posted on 2020-07-01
4961 An in-vitro BBB-on-a-chip open model of human blood-brain barrier enabling advanced optical imaging
Salman, M.; Marsh, G.; Kusters, I.; Delince, M.; Di Caprio, G.; Upadhyayula, S.; De Nola, G.; Hunt, R.; Ohashi, K. G.; Shimizu, F.; Sano, Y.; Kanda, T.; Obermeier, B.; Kirchhausen, T.
10.1101/2020.06.30.175380 — bioengineering — Posted on 2020-07-01
4963 Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice
Goldblum, R. R.; McClellan, M.; Hou, C.; Thompson, B. R.; White, K.; Vang, H. X.; Cohen, H.; Metzger, J. M.; Gardner, M. K.
10.1101/2020.06.30.174532 — cell biology — Posted on 2020-07-01
4964 SWR1-independent association of H2A.Z to the LINC complex promotes meiotic chromosome motion
Gonzalez-Arranz, S.; Gardner, J. M.; Yu, Z.; Patel, N. J.; Heldrich, J.; Santos, B.; Carballo, J. A.; Jaspersen, S.; Hochwagen, A.; San-Segundo, P. A.
10.1101/2020.06.30.181016 — cell biology — Posted on 2020-07-01
4965 Capturing limbal epithelial stem cell population dynamics, signature and their niche
Altshuler, A.; Amitai Lange, A.; Tarazi, N.; Dey, S.; Strinkovsky, L.; Bhattacharya, S.; Hadad-Porat, S.; Nasser, W.; Imeri, J.; Ben-David, G.; Tiosano, B.; Berkowitz, E.; Karin, N.; Savir, Y.; Shalom-Feuerstein, R.
10.1101/2020.06.30.179754 — cell biology — Posted on 2020-07-01
4967 Reconstitution of contractile actomyosin rings in vesicles
Litschel, T.; Kelley, C. F.; Holz, D.; Adeli Koudehi, M.; Vogel, S. K.; Burbaum, L.; Mizuno, N.; Vavylonis, D.; Schwille, P.
10.1101/2020.06.30.180901 — synthetic biology — Posted on 2020-07-01
4970 Organic Dust Exposure Induces Stress Response and Mitochondrial Dysfunction in Monocytic Cells
Mahadev-Bhat, S.; Shrestha, D.; Massey, N.; Karriker, L. A.; Kanthasamy, A.; Charavaryamath, C.
10.1101/2020.06.30.180323 — cell biology — Posted on 2020-07-01
4971 The ribosome modulates folding inside the ribosomal exit tunnel
Wruck, F.; Tian, P.; Kudva, R.; Best, R. B.; von Heijne, G.; Tans, S. J.; Katranidis, A.
10.1101/2020.06.30.180224 — biophysics — Posted on 2020-07-01
4972 Accurate chromosome-scale haplotype-resolved assembly of human genomes
Garg, S.; Arkarachai Fungtammasan, A.; Carroll, A.; Chou, M.; Schmitt, A.; Zhou, X.; Mac, S.; Peluso, P.; Hatas, E.; Ghurye, J.; Maguire, J.; Mahmoud, M.; Cheng, H.; Heller, D.; Zook, J. M.; Moemke, T.; Marschall, T.; Sedlazeck, F. J.; Aach, J.; Chin, C.-S.; Church, G. M.; Li, H. M.
10.1101/810341 — bioinformatics — Posted on 2020-07-01
4973 Elucidation of global and local epidemiology of Salmonella Enteritidis through multilevel genome typing
Luo, L.; Payne, M.; Kaur, S.; Hu, D.; Cheney, L.; Octavia, S.; Wang, Q.; Tanaka, M. M.; Sintchenko, V.; Lan, R.
10.1101/2020.06.30.169953 — genomics — Posted on 2020-07-01
4974 Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
Vinayagam, D.; Quentin, D.; Sitsel, O.; Merino, F.; Stabrin, M.; Hofnagel, O.; Yu, M.; Ledeboer, M. W.; Malojcic, G.; Raunser, S.
10.1101/2020.06.30.180778 — biochemistry — Posted on 2020-07-01
4975 Mechanotransduction and dynamic outflow regulation in trabecular meshwork requires Piezo1 channels
Yarishkin, O.; Phuong, T. T. T.; Baumann, J. M.; De Ieso, M. L.; Vazquez-Chona, F.; Rudzitis, C. N.; Sundberg, C.; Lakk, M.; Stamer, W. D.; Krizaj, D.
10.1101/2020.06.30.180653 — physiology — Posted on 2020-07-01
4976 USP11 deubiquitinates monoubiquitinated SPRTN to repair DNA-protein crosslinks
Perry, M.; Kollala, S. S.; Biegert, M.; Su, G.; Kodavati, M.; Mallard, H.; Kreiling, N.; Holbrook, A.; Ghosal, G.
10.1101/2020.06.30.180471 — molecular biology — Posted on 2020-07-01
4980 High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells
Yan, X.; Stuurman, N.; Ribeiro, S. A.; Tanenbaum, M. E.; Horlbeck, M. A.; Liem, C. R.; Jost, M.; Weissman, J. S.; Vale, R.
10.1101/2020.06.30.179648 — cell biology — Posted on 2020-07-01
4981 Identification of novel HPFH-like mutations by CRISPR base editing that elevates the expression of fetal hemoglobin
Ravi, N. S.; Wienert, B.; Wyman, S. K.; Vu, J.; Pai, A. A.; Balasubramanian, P.; Nakamura, Y.; Kurita, R.; Marepally, S.; Thangavel, S.; Velayudhan, S. R.; Srivastava, A.; DeWitt, M. A.; Corn, J. E.; Mohankumar, K. M.
10.1101/2020.06.30.178715 — genomics — Posted on 2020-07-01
4982 Stochastic Analysis Probes the Role of the Chaperone Hfq in E. coli Sugar Shock Response
Bianchi, D. M.; Brier, T. A.; Poddar, A.; Azam, M. S.; Vanderpool, C. K.; Ha, T.; Luthey-Schulten, Z.
10.1101/2020.06.30.178566 — biophysics — Posted on 2020-07-01
4985 Light into the darkness: Unifying the known and unknown coding sequence space in microbiome analyses
Vanni, C.; Schechter, M.; Acinas, S.; Barberan, A.; Buttigieg, P. L.; Casamayor, E. O.; Delmont, T. O.; Duarte, C. M.; Eren, A. M.; Finn, R.; Mitchell, A.; Sanchez, P.; Siren, K.; Steinegger, M.; Glöckner, F. O.; Fernandez-Guerra, A.
10.1101/2020.06.30.180448 — microbiology — Posted on 2020-07-01
4989 Cryo-EM structures reveal a multistep mechanism of Hsp90 activation by co-chaperone Aha1
Liu, Y.; Sun, M.; Myasnikov, A. G.; Elnatan, D.; Delaeter, N.; Nguyenquang, M.; Agard, D.
10.1101/2020.06.30.180695 — biophysics — Posted on 2020-07-01
4990 Structure of Full Length Plasmodium Myosin A and its light chain PfELC, dual targets against malaria parasite pathogenesis
Moussaoui, D.; Robblee, J. P.; Auguin, D.; Krementsova, E. B.; Haase, S.; Blake, T. C. A.; Baum, J.; Robert-Paganin, J.; Trybus, K. M.; Houdusse, A.
10.1101/2020.06.30.179788 — biochemistry — Posted on 2020-07-01
4992 Diversification of the restriction modification system of Streptococcus pyogenes through its acquisition of mobile elements
Ota, A.; Nishiuchi, Y.; Nakanishi, N.; Iijima, Y.; Iwamoto, T.; Osaki, K.; Ogura, Y.; Toyoda, A.; Suzuki, Y.; Hayashi, T.; Ohge, H.; Mori, H.; Ato, M.; MARUYAMA, F.
10.1101/2020.06.30.179317 — microbiology — Posted on 2020-07-01
4993 Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target
Sobala, L. F.; Fernandes, P. Z.; Hakki, Z.; Thompson, A. J.; Howe, J. D.; Hill, M.; Zitzmann, N.; Davies, S.; Stamataki, Z.; Butters, T. D.; Alonzi, D. S.; Williams, S. J.; Davies, G. J.
10.1101/2020.06.30.179523 — biochemistry — Posted on 2020-07-01
4995 Single neurons throughout human memory regions phase-lock to hippocampal theta
Schonhaut, D. R.; Ramayya, A. G.; Solomon, E. A.; Herweg, N. A.; Fried, I.; Kahana, M. J.
10.1101/2020.06.30.180174 — neuroscience — Posted on 2020-07-01
4996 Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress
Pace, S. A.; Christensen, C.; Schackmuth, M. K.; Wallace, T.; McKlveen, J. M.; Beischel, W.; Morano, R. L.; Scheimann, J. R.; Wilson, S. P.; Herman, J. P.; Myers, B.
10.1101/2020.06.30.181115 — neuroscience — Posted on 2020-07-01
4999 Spatial and single-cell transcriptional landscape of human cerebellar development
Aldinger, K. A.; Thomson, Z.; Haldipur, P.; Deng, M.; Timms, A. E.; Hirano, M.; Santpere, G.; Roco, C.; Rosenberg, A. B.; Lorente-Galdos, B.; Gulden, F. O.; O'Day, D.; Overman, L. M.; Lisgo, S.; Alexandre, P.; Sestan, N.; Doherty, D.; Dobyns, W. B.; Seelig, G.; Glass, I. A.; Millen, K. J.
10.1101/2020.06.30.174391 — developmental biology — Posted on 2020-07-01
5000 Attenuated Subcomponent Vaccine Design Targeting the SARS-CoV-2 Nucleocapsid Phosphoprotein RNA Binding Domain: In silico analysis
Chukwudozie, O. S.; Chukwuanukwu, R. C.; Onyekachi, I. O.; Daniel, E. M.; Vincent, D. C.; Onaopemipo, D.-A. T.; David, K. B.; Taiwo, B. T.; Perpetua, O. C.; Elizabeth, O. U.
10.1101/2020.06.30.176537 — immunology — Posted on 2020-07-01
5003 Decoding spoken English phonemes from intracortical electrode arrays in dorsal precentral gyrus
Wilson, G. H.; Stavisky, S. D.; Willett, F. R.; Avansino, D. T.; Kelemen, J. N.; Hochberg, L. R.; Henderson, J. M.; Druckmann, S.; Shenoy, K. V.
10.1101/2020.06.30.180935 — neuroscience — Posted on 2020-07-01
5004 Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro
Bobrowski, T.; Chen, L.; Eastman, R. T.; Itkin, Z.; Shinn, P.; Chen, C.; Guo, H.; Zheng, W.; Michael, S.; Simeonov, A.; Hall, M.; Zakharov, A. V.; Muratov, E. N.
10.1101/2020.06.29.178889 — microbiology — Posted on 2020-07-01
5005 Complete vertebrate mitogenomes reveal widespread gene duplications and repeats
Formenti, G.; Rhie, A.; Balacco, J.; Haase, B.; Mountcastle, J.; Fedrigo, O.; Brown, S.; Capodiferro, M.; Al-Ajli, F. O.; The Vertebrate Genomes Project Consortium, ; Ambrosini, R.; Houde, P.; Koren, S.; Oliver, K.; Smith, M.; Skelton, J.; Betteridge, E.; Dolucan, J.; Corton, C.; Bista, I.; Torrance, J.; Tracey, A.; Uliano-Silva, M.; Howe, K.; McCarthy, S.; Winkler, S.; Kwak, W.; Korlach, J.; Fungtammasan, A.; Fordham, D.; Costa, V.; Mayes, S.; Chiara, M.; Horner, D. S.; Myers, E. W.; Durbin, R.; Achilli, A.; Braun, E. L.; Phillippy, A. M.; Jarvis, E. D.
10.1101/2020.06.30.177956 — genomics — Posted on 2020-07-01
5008 Importin α2 associates with chromatin via a novel DNA binding domain
Jibiki, K.; Kodama, T.; Suenaga, A.; Kawase, Y.; Shibazaki, N.; Nomoto, S.; Nagasawa, S.; Nagashima, M.; Shimodan, S.; Kikuchi, R.; Saitoh, N.; Yoneda, Y.; Akagi, K.-i.; Yasuhara, N.
10.1101/2020.05.04.075580 — molecular biology — Posted on 2020-07-01
5012 Multiple evolutionary pathways to achieve thermal adaptation in small mammals
Colella, J. P.; Tigano, A.; Dudchenko, O.; Omer, A. D.; Khan, R.; Bochkov, I. D.; Aiden, E. L.; MacManes, M. D.
10.1101/2020.06.29.178392 — evolutionary biology — Posted on 2020-07-01
5013 Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Kildisiute, G.; Kholosy, W. M.; Young, M. D.; Roberts, K.; Elmentaite, R.; van Hooff, S. R.; Khabirova, E.; Piapi, A.; Thevanesan, C.; Bugallo Blanco, E.; Burke, C.; Mamanova, L.; Lijnzaad, P.; Margaritis, T.; Holstege, F. C. P.; Tas, M. L.; Wijnen, M. H. W. A.; van Noesel, M. M.; del Valle, I.; Barone, G.; van der Linden, R.; Duncan, C.; Anderson, J.; Achermann, J. C.; Haniffa, M.; Teichmann, S. C. P.; Rampling, D.; Sebire, N. J.; He, X.; de Krijger, R. R.; Barker, R. A.; Meyer, K. B.; Bayraktar, O.; Straathof, K.; Molenaar, J. J.; Behjati, S.
10.1101/2020.06.22.164301 — cancer biology — Posted on 2020-07-01
5014 The effectiveness of prevention and early detection of tuberculosis in people living with HIV
Sinitsyn, M.; Belilovsky, E.; Bogorodskaya, E.; Borisov, S.; Kudlay, D.; Slogotskaya, L.
10.1101/2020.06.30.179895 — immunology — Posted on 2020-07-01