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Archive, 2023-09

2 Functional metabolomics of the human scalp: A metabolic niche for Staphylococcus epidermidis
Nothias, L.-F.; Schmid, R.; Garlet, A.; Cameron, H.; Leoty-Okombi, S.; Andre-Frei, V.; Fuchs, R.; Dorrestein, P.; Ternes, P.
10.1101/2023.03.26.532286 — systems biology — Posted on 2023-09-30
3 Phylogenetic analysis of ABCE genes across the plant kingdom
Jakobson, L.; Mottus, J.; Suurvali, J.; Somera, M.; Tarassova, J.; Nigul, L.; Smolander, O.-P.; Sarmiento, C.
10.1101/2023.09.29.560150 — evolutionary biology — Posted on 2023-09-30
5 An updated model of shoot apical meristem regulation by ERECTA family and CLAVATA3 signaling pathways
Uzair, M.; Urquidi-Camacho, R. A.; Liu, Z.; Overholt, A. M.; DeGennaro, D.; Zhang, L.; Herron, B. S.; Hong, T.; Shpak, E. D.
10.1101/2023.09.29.560237 — plant biology — Posted on 2023-09-30
7 Elasticity of the HIV-1 Core Facilitates Nuclear Entry and Infection
Deshpande, A.; Bryer, A. J.; Andino, J.; Shi, J.; Hong, J.; Torres, C.; Harel, S.; Francis, A.; Perilla, J. R.; Aiken, C.; Rousso, I.
10.1101/2023.09.29.560083 — biophysics — Posted on 2023-09-30
8 Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes
Sauer, P. V.; Cupellini, L.; Sutter, M.; Bondanza, M.; Dominguez Martin, M. A.; Kirst, H.; Bina, D.; Koh, A. F.; Kotecha, A.; Greber, B. J.; Nogales, E.; Polivka, T.; Mennucci, B.; Kerfeld, C. A.
10.1101/2023.09.30.560311 — biophysics — Posted on 2023-09-30
11 Mfsd7b facilitates choline uptake and missense mutations affect choline transport function
Ha, T. T. H.; Sukumar, V. K.; Chua, J. W. B.; Nguyen, D. T.; Nguyen, T. Q.; Lim, L. H. K.; Cazenave-Gassiot, A.; Nguyen, L. N.
10.1101/2023.09.30.560304 — biochemistry — Posted on 2023-09-30
15 Impact of whole-genome duplications on structural variant evolution in the plant genus Cochlearia
Hamala, T.; Moore, C.; Cowan, L.; Carlile, M.; Gopaulchan, D.; Brandrud, M. K.; Birkeland, S.; Loose, M.; Kolar, F.; Koch, M. A.; Yant, L.
10.1101/2023.09.29.560073 — evolutionary biology — Posted on 2023-09-30
16 A Web Service for Automated Design of Multiple Types of Ribozymes Targeting RNA: from minimal hammerhead to aptazymes
Najeh, S.; Kharma, N.; Vaudry-Read, T.; Haurie, A.; Paslawski, C.; Adams, D.; Ferreira, S.; Perreault, J.
10.1101/2023.09.30.560155 — molecular biology — Posted on 2023-09-30
17 Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aging Brain
Mancino, S.; Seneviratne, J.; Mupo, A.; Krueger, F.; Oxley, D.; Eckersley-Maslin, M.; da Rocha, S. T.
10.1101/2023.09.29.560184 — molecular biology — Posted on 2023-09-30
18 Successive responses of three coral holobiont components (coral hosts, symbiotic algae, and bacteria) to daily temperature fluctuations
Hsieh, Y. E.; Lu, C.-Y.; Liu, P.-Y.; Kao, J.-M.; Yang, S.-Y.; Wu, C.-Y.; Wong, J.-W. M.; Shikina, S.; Fan, T.-Y.; Yang, S.-H.
10.1101/2023.09.30.560297 — microbiology — Posted on 2023-09-30
19 A mobile intron facilitates interference competition between co-infecting viruses
Birkholz, E. A.; Morgan, C. J.; Laughlin, T. G.; Lau, R. K.; Prichard, A.; Rangarajan, S.; Meza, G. N.; Lee, J.; Armbruster, E. G.; Suslov, S.; Pogliano, K.; Meyer, J. R.; Villa, E.; Corbett, K. D.; Pogliano, J.
10.1101/2023.09.30.560319 — microbiology — Posted on 2023-09-30
20 The Identification of IL-4 as a Regulator of Chimeric Antigen Receptor T Cell Exhaustion
Stewart, C. M.; Siegler, E. L.; Sakemura, R. L.; Cox, M. J.; Huynh, T.; Kimball, B.; Mai, L.; Can, I.; Manriquez Roman, C.; Yun, K.; Sirpilla, O.; Girsch, J. H.; Ogbodo, E.; Ismail, W.; Gaspar-Maia, A.; Budka, J.; Kim, J.; Scholler, N.; Mattie, M.; Filosto, S.; Kenderian, S. S.
10.1101/2023.09.28.560046 — immunology — Posted on 2023-09-30
21 Probiotic neoantigen delivery vectors for precision cancer immunotherapy
Redenti, A.; Im, J.; Redenti, B.; Li, F.; Rouanne, M.; Sheng, Z.; Sun, W.; Gurbatri, C. R.; Huang, S.; Komaranchath, M.; Jang, Y.; Hahn, J.; Ballister, E. R.; Vincent, R. L.; Vardoshivilli, A.; Danino, T.; Arpaia, N.
10.1101/2023.09.29.560228 — synthetic biology — Posted on 2023-09-30
25 Revisiting the origins of the Sobemovirus genus: a case for ancient origins of plant viruses
Ghafari, M.; Somera, M.; Sarmiento, C.; Niehl, A.; Hebrard, E.; Tsoleridis, T.; Ball, J.; Moury, B. k.; Lemey, P.; Katzourakis, A.; Fargette, D.
10.1101/2023.09.29.560145 — evolutionary biology — Posted on 2023-09-30
30 BiP/GRP78 is a pro-viral factor for diverse dsDNA viruses that promotes the survival and proliferation of cells upon KSHV infection
Najarro, G.; Brackett, K.; Woosley, H.; Faeldonea, C.; Moreno, O. K.; Ramirez Negron, A.; Love, C.; Ward, R.; Langelier, C.; Gardner, B. M.; Arias, C.
10.1101/2023.09.29.560238 — microbiology — Posted on 2023-09-30
31 T cells in testicular germ cell tumors: new evidence of fundamental contributions by rare subsets
Islam, R.; Heyer, J.; Figura, M.; Wang, X.; Nie, X.; Nathaniel, B.; Indumathy, S.; Hartmann, K.; Pleuger, C.; Fijak, M.; Kliesch, S.; Dittmar, F.; Pilatz, A.; Wagenlehner, F.; Hedger, M.; Loveland, B.; Hotaling, J. H.; Guo, J.; Loveland, K.; Schuppe, H.-C.; Fietz, D.
10.1101/2023.09.28.559963 — cancer biology — Posted on 2023-09-30
32 IL-1B-mediated inflammatory signaling drives ineffective erythropoiesis in early-stage myelodysplastic syndromes
Adema, V.; Ganan-Gomez, I.; Ma, F.; Rodriguez-Sevilla, J. J.; Chien, K.; Yang, H.; Thongon, N.; Kanagal-Shamanna, R.; Loghavi, S.; Montalban-Bravo, G.; Hammond, D.; Gu, Y.; Tan, R.; Tan, L.; Lorenzi, P.; Al-Atrash, G.; Clise-Dwyer, K.; Bejar, R.; Pellegrini, M.; Garcia-Manero, G.; Colla, S.
10.1101/2023.09.28.560018 — cancer biology — Posted on 2023-09-30
33 Digital profiling of cancer transcriptomes from histology images with grouped vision attention
Zheng, Y.; Pizurica, M.; Carrillo-Perez, F.; Noor, H.; Yao, W.; Wohlfart, C.; Marchal, K.; Vladimirova, A.; Gevaert, O.
10.1101/2023.09.28.560068 — bioinformatics — Posted on 2023-09-30
34 Removing bias in sequence models of protein fitness
Shaw, A. Y.; Spinner, H. B.; Gurev, S.; Shin, J.-E.; Rollins, N.; Marks, D. S.
10.1101/2023.09.28.560044 — bioinformatics — Posted on 2023-09-30
38 HyperPRI: A Dataset of Hyperspectral Images for Underground Plant Root Study
Chang, S. J.; Chowdhry, R.; Song, Y.; Mejia, T.; Hampton, A.; Kucharski, S.; Sazzad, T.; Zhang, Y.; Koppal, S. J.; Wilson, C. H.; Gerber, S.; Tillman, B.; Resende, M. F.; Hammond, W. M.; Zare, A.
10.1101/2023.09.29.559614 — plant biology — Posted on 2023-09-30
42 Replicated Functional Evolution in Cichlid Adaptive Radiations
Martinez, C. M.; Corn, K. A.; Williamson, S.; Satterfield, D. R.; Roberts-Hugghis, A. S.; Barley, A.; Borstein, S. R.; McGee, M. D.; Wainwright, P. C.
10.1101/2023.09.30.559334 — evolutionary biology — Posted on 2023-09-30
47 Cerebellum-Midbrain Reward Circuitry in Humans: an in vivo dissection
Hoffman, L. J.; Leong, J. K.; Sullivan-Toole, H.; Foley, J.; Elliott, B. L.; Olson, I. R.
10.1101/2023.09.29.560239 — neuroscience — Posted on 2023-09-30
49 Systematic Profiling of Ale Yeast Protein Dynamics across Fermentation and Repitching
Garge, R. K.; Geck, R. C.; Armstrong, J. O.; Dunn, B.; Boutz, D. R.; Battenhouse, A.; Leutert, M.; Dang, V.; Jiang, P.; Kwiatkowski, D.; Peiser, T.; McElroy, H.; Marcotte, E. M.; Dunham, M. J.
10.1101/2023.09.21.558736 — systems biology — Posted on 2023-09-30
50 The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics
Mc Cartney, A. M.; Formenti, G.; Mouton, A.; De Panis, D.; Marins, L. S.; Leitao, H. G.; Diedericks, G.; Kirangwa, J.; Morselli, M.; Salces, J.; Escudero, N.; Iannucci, A.; Natali, C.; Svardal, H.; Fernandez, R.; De Pooter, T.; Joris, G.; Strazisar, M.; Wood, J.; Herron, K. E.; Seehausen, O.; Watts, P. C.; Shaw, F.; Davey, R. P.; Minotto, A.; Fernandez Gonzalez, J. M.; Bohne, A.; Alegria, C.; Alioto, T.; Alves, P. C.; Amorim, I. R.; Aury, J.-M.; Backstrom, N.; Baldrian, P.; Ballarin, L.; Baltrunaite, L.; Barta, E.; BedHom, B.; Belser, C.; Bergsten, J.; Bertrand, L.; Bilandija, H.; Binzer-Panch
10.1101/2023.09.25.559365 — genomics — Posted on 2023-09-30
52 Scaling laws of human transcriptional activity
Hong, J.; Cavga, A. D.; Shah, D.; Laue, E. D.; Taipale, J.
10.1101/2023.08.10.551625 — genetics — Posted on 2023-09-30
53 Statistics to prioritize rare variants in family-based sequencing studies with disease subtypes
Nieuwoudt, C.; Binte Farooq, F.; Graham, J.; Brooks-WIlson, A.; Bureau, A.; Brooks-Wilson, A.
10.1101/2023.09.28.560053 — genetics — Posted on 2023-09-30
54 Deep learning reveals the role of copy number variation in the genetic architecture of a highly polymorphic sexual trait
van der Bijl, W.; Shu, J.; Goberdhan, V. S.; Sherin, L.; Cortazar-Chinarro, M.; Corral-Lopez, A.; Mank, J. E.
10.1101/2023.09.29.560175 — evolutionary biology — Posted on 2023-09-30
57 Convergent generation of atypical prions in knock-in mouse models of genetic prion disease
Mehra, S.; Bourkas, M. E. C.; Kaczmarczyk, L.; Stuart, E.; Arshad, H.; Griffin, J. K.; Frost, K. L.; Walsh, D. J.; Supattapone, S.; Booth, S. A.; Jackson, W. S.; Watts, J. C.
10.1101/2023.09.26.559572 — neuroscience — Posted on 2023-09-30
61 Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cellgenomics
Rexach, J. E.; Cheng, Y.; Chen, L.; Polioudakis, D.; Lin, L.-C.; Mitri, V.; Elkins, A.; Yin, A.; Calini, D.; Kawaguchi, R.; Ou, J.; Huang, J.; Williams, C.; Robinson, J.; Gaus, S.; Spina, S.; Lee, E.; Grinberg, L.; Vinters, H.; Trojanowski, J.; Seeley, W.; Molhatra, D.; Geschwind, D.
10.1101/2023.09.29.560245 — neuroscience — Posted on 2023-09-30
62 Genetic Screen in a Pre-Clinical Model of High-Grade Complex Karyotype Sarcoma Characterizes Drivers of Distinct Sarcoma Subtypes and Identifies New Therapeutic Vulnerabilities
Munoz, M. A.; Freeland, J.; O'Donnell, E.; Langerman, J.; Bergonio, J.; Surarez-Navarro, J.; Darrow, M.; Thorpe, S.; Randall, R.; Carraway, K. L.; Witte, O.; Graeber, T.; Carr-Ascher, J.
10.1101/2022.06.13.495815 — cancer biology — Posted on 2023-09-30
65 A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Andradi-Brown, C.; Wichers-Misterek, J. S.; von Thien, H.; Hoeppner, Y. D.; Scholz, J. A. M.; Smedegaard Hansson, H.; Filtenborg Hocke, E.; Gilberger, T. W.; Duffy, M.; Lavstsen, T.; Baum, J.; Otto, T. D.; Cunnington, A. J.; Bachmann, A.
10.1101/2023.03.21.533599 — bioinformatics — Posted on 2023-09-30
67 Olivar: automated variant aware primer design for multiplex tiled amplicon sequencing of pathogens
Wang, M. X.; Lou, E. G.; Sapoval, N.; Kim, E.; Kalvapalle, P.; Kille, B.; Elworth, R. A. L.; Liu, Y.; Fu, Y.; Stadler, L. B.; Treangen, T. J.
10.1101/2023.02.11.528155 — bioinformatics — Posted on 2023-09-30
68 Mapping Cell-to-cell Interactions from Spatially Resolved Transcriptomics Data
Zhu, J. Z.; Wang, Y.; Chang, W. Y.; Malewska, A.; Napolitano, F.; Gahan, J. C.; Unni, N.; Zhao, M.; Wu, F.; Guo, L.; Zhao, Z.; Chen, D. Z.; Hannan, R.; Zhang, S.; Xiao, G.; Mu, P.; Hanker, A. B.; Strand, D.; Arteaga, C. L.; Desai, N.; Wang, X.; Xie, Y.; Wang, T.
10.1101/2023.09.18.558298 — bioinformatics — Posted on 2023-09-30
70 Factors Affecting Protein Recovery During Hsp40 Affinity Profiling
Montoya, M. R.; Quanrud, G. M.; Mei, L.; Montano, J. L.; Hong, C.; Genereux, J. C.
10.1101/2022.03.31.485989 — biochemistry — Posted on 2023-09-30
71 ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies
Bartolome, A.; Heiby, J. C.; Di Fraia, D.; Heinze, I.; Knaudt, H.; Spaeth, E.; Omrani, O.; Minetti, A.; Hofmann, M.; Kirkpatrick, J. M.; Dau, T.; Ori, A.
10.1101/2022.08.09.503299 — biochemistry — Posted on 2023-09-30
73 Sex differences in binge alcohol drinking and the behavioral consequences of protracted abstinence in C57BL/6J mice
Rivera-Irizarry, J. K.; Zallar, L. J.; Levine, O. B.; Skelly, M. J.; Boyce, J. E.; Barney, T.; Kopyto, R.; Pleil, K. E.
10.1101/2023.05.12.540565 — animal behavior and cognition — Posted on 2023-09-30
74 High genetic load without purging in a diverse species-at-risk
Taylor, R. S.; Manseau, M.; Keobouasone, S.; Liu, P.; Mastromonaco, G.; Solmundson, K.; Kelly, A.; Larter, N. C.; Gamberg, M.; Schwantje, H.; Thacker, C.; Polfus, J.; Andrew, L.; Hervieux, D.; Simmons, D.; Wilson, P. J.
10.1101/2022.12.19.521038 — genomics — Posted on 2023-09-30
75 The Genetic Architecture of Multimodal Human Brain Age
Wen, J.; Zhao, B.; Yang, Z.; Erus, G.; Skampardoni, I.; Mamourian, E.; Cui, Y.; Hwang, G.; Bao, J.; Boquet-Pujadas, A.; Zhou, Z.; Veturi, Y.; Ritchie, M. D.; Thompson, P.; Shou, H.; Shen, L.; Toga, A. W.; Davatzikos, C.
10.1101/2023.04.13.536818 — genetics — Posted on 2023-09-30
76 Evolutionary computing to assemble standing genetic diversity and achieve long-term genetic gain
Villiers, K.; Voss-Fels, K. P.; Dinglasan, E.; Jacobs, B.; Hickey, L.; Hayes, B. J.
10.1101/2023.05.05.539510 — genetics — Posted on 2023-09-30
83 AMPK Regulates Phagophore-to-Autophagosome Maturation
Barnaba, C.; Broadbent, D. G.; Perez, G. I.; Schmidt, J. C.
10.1101/2023.09.28.559981 — cell biology — Posted on 2023-09-30
85 Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
Meineke, B.; Heimgärtner, J.; Caridha, R.; Block, M.; Kimler, K. J.; Pires, M. F.; Landreh, M.; Elsässer, S. J.
10.1101/2023.03.26.534279 — cell biology — Posted on 2023-09-30
88 T cell migration requires ion and water influx to regulate actin polymerization
de Boer, L.; Vanes, L.; Melgrati, S.; Biggs O'May, J.; Hayward, D.; Driscoll, P.; Day, J.; Griffiths, A.; Magueta, R.; Morrell, A.; MacRae, J. I.; Koechl, R.; Tybulewicz, V.
10.1101/2022.03.16.484584 — immunology — Posted on 2023-09-30
89 The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection
Quintana Alcala, J. F.; Sinton, M. C.; Chandrasegaran, P.; Dubey, L. K.; Ogunsola, J.; Samman, M. A.; Haley, M.; McConnell, G.; Kuispond Swar, N. R.; Ngoyi, D. M.; Bending, D.; de Lecea, L.; MacLeod, A.; Mabbott, N. A.
10.1101/2023.04.30.538710 — immunology — Posted on 2023-09-30
90 Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3
Mytych, J. S.; Pan, Z.; Lopez-Davis, C.; Redinger, N.; Lawrence, C.; Ziegler, J.; Popescu, N. I.; James, J. A.; Farris, A. D.
10.1101/2023.03.30.535001 — immunology — Posted on 2023-09-30
91 WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses
Biggs O'May, J.; Vanes, L.; de Boer, L.; Hartweger, H.; Kunzelmann, S.; Hayward, D.; Llorian, M.; Lewis, D. A.; Koechl, R.; Tybulewicz, V.
10.1101/2022.03.16.484637 — immunology — Posted on 2023-09-30
97 Predictors for Estimating Subcortical EEG Responses to Continuous Speech
Kulasingham, J. P.; Bachmann, F. L.; Eskelund, K.; Enqvist, M.; Alickovic, E.; Innes-Brown, H.
10.1101/2023.03.01.530635 — neuroscience — Posted on 2023-09-30
101 Sustained hyperglycemia specifically targets translation of mRNAs for insulin secretion
Cheruiyot, A.; Hollister-Lock, J.; Sullivan, B.; Pan, H.; Dreyfuss, J. M.; Bonner-Weir, S.; Schaffer, J. E.
10.1101/2023.09.29.560203 — cell biology — Posted on 2023-09-29
102 A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans
Vanderperre, B.; Muraleedharan, A.; Dorion, M.-F.; Larroquette, F.; Del Cid Pellitero, E.; Rajakulendran, N.; Chen, C. X.- Q.; Lariviere, R.; Michaud-Tardif, C.; Chidiac, R.; Lipuma, D.; Macleod, G.; Thomas, R.; Wang, Z.; Reintsch, W. E.; Luo, W.; Shlaifer, I.; Zhang, F.; Xia, K.; Steinhart, Z.; Linhardt, R. J.; Trempe, J.-F.; Liu, J.; Durcan, T.; Angers, S.; Fon, E. A.
10.1101/2023.09.29.560170 — cell biology — Posted on 2023-09-29
105 Transcriptome analysis in a humanized mouse model of familial dysautonomia reveals tissue-specific gene expression disruption in the peripheral nervous system.
GAO, D.; Harripaul, R. S.; Morini, E. S.; Slaugenhaupt, S.; Chekuri, A.; Logan, E.; Kirchner, E. G.; Bolduc, J.; Erdin, S.; Yadav, R.; Talkowski, M. E.; Salani, M.; Currall, B.
10.1101/2023.09.28.559870 — genomics — Posted on 2023-09-29
106 Integrated organismal responses induced by ecologically-relevant pCO2 and temperature exposures in developing lake sturgeon
Belding, L. D.; Thorstensen, M. J.; Quijada-Rodriguez, A.; Bugg, W. S.; Yoon, G. R.; Loeppky, A. R.; Allen, G. J. P.; Schoen, A. N.; Earhart, M. L.; Brandt, C.; Ali, J. L.; Weihrauch, D.; Jeffries, K. M.; Anderson, W. G.
10.1101/2023.09.28.559814 — zoology — Posted on 2023-09-29
111 Voluntary wheel running mitigates disease in an Orai1 gain-of-function mouse model of tubular aggregate myopathy
O'Connor, T. N.; Zhao, N.; Orciuoli, H. M.; Brasile, A.; Pietrangelo, L.; He, M.; Groom, L.; Leigh, J.; Mahamed, Z.; Liang, C.; Malik, S.; Protasi, F.; Dirksen, R. T.
10.1101/2023.09.29.559036 — physiology — Posted on 2023-09-29
112 A Sodium-dependent Trehalose Transporter Contributes to Anhydrobiosis in Insect Cell Line, Pv11
Mizutani, K.; Yoshida, Y.; Nakanishi, E.; Miyata, Y.; Tokumoto, S.; Fuse, H.; Gusev, O.; Kikuta, S.; Kikawada, T.
10.1101/2023.09.29.560116 — biochemistry — Posted on 2023-09-29
114 Genetic diversity of domestic cat hepadnavirus in Taiwan
Silva, B. B. I.; Chen, J.-Y.; Villanueva, B. H. A.; Lu, Z.-Y.; Zhen, H.-H.; Montecillo, A. D.; Shofa, M.; Minh, H.; Chuang, J.-P.; Huang, H.-Y.; Saito, A.; Chuang, K.-P.
10.1101/2023.09.29.560097 — genetics — Posted on 2023-09-29
115 Mitochondrial regulator PGC-1a in neuronal metabolism and brain aging
Souder, D. C.; McGregor, E. R.; Rhoads, T. W.; Clark, J. P.; Porter, T. J.; Elicieri, K. W.; Moore, D. L.; Pugliellli, L.; Anderson, R. M.
10.1101/2023.09.29.559526 — cell biology — Posted on 2023-09-29
118 Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV
Davis, C.; Epifano, I.; Dee, K.; McFarlane, S.; Wojtus, J. K.; Brennan, B.; Gu, Q.; Vattipally, S. B.; Tong, L.; Orr, L.; Filipe, A. D. S.; Ho, A.; Thomson, E. C.; Boutell, C.
10.1101/2023.09.29.560106 — microbiology — Posted on 2023-09-29
119 B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients
Kaminski, J.; Fleming, R. A.; Alvarez-Calderon, F.; McGuckin, C.; Ho, E. E.; Eng, F.; Rui, X.; Keskula, P.; Cagnin, L.; Charles, J.; Zavistaski, J.; Margossian, S. P.; Kapadia, M. A.; Rottman, J. B.; Lane, J.; Baumeister, S. H. C.; Tkachev, V.; Shalek, A. K.; Kean, L. S.; Gerdemann, U.
10.1101/2023.09.28.559936 — immunology — Posted on 2023-09-29
120 Genotypic and resistance profile analysis of two oat crown rust differential sets urge coordination and standardisation
Nguyen, D. T.; Henningsen, E. C.; Lewis, D. C.; Mago, R.; McNeil, M.; Suchecki, R.; Boden, S.; Sperschneider, J.; Kianian, S.; Dodds, P. N.; Figueroa, M.
10.1101/2023.09.28.559455 — plant biology — Posted on 2023-09-29
121 A Small Multidrug Resistance Transporter in Pseudomonas aeruginosa Confers Substrate-Specific Resistance or Susceptibility
Wegrzynowicz, A. K.; Heelan, W. J.; Demas, S. P.; McLean, M. S.; Peters, J. M.; Henzler-Wildman, K. A.
10.1101/2023.09.28.560013 — biochemistry — Posted on 2023-09-29
123 In vivo dissection of the mouse tyrosine catabolic pathway with CRISPR-Cas9 identifies modifier genes affecting hereditary tyrosinemia type 1
Rivest, J.-F.; Carter, S.; Goupil, C.; Cyr, D.; Ung, R.-V.; Dal Soglio, D.; Mac-Way, F.; Waters, P. J.; Paganelli, M.; Doyon, Y.
10.1101/2023.09.29.559947 — genetics — Posted on 2023-09-29
125 Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load
Gutierrez-Sanchez, M.; Zhang, S.; Gharsallah, C.; Lamotte, S.; Varet, H.; Legendre, R.; Dingli, F.; Loew, D.; Rotili, D.; Valente, S.; Mai, A.; Loiseau, P.; Pomel, S.; Jung, M.; Lecoeur, H.; Prina, E.; Spaeth, G. F.
10.1101/2023.09.29.560133 — cell biology — Posted on 2023-09-29
128 Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation
Feng, L.; Barrows, D.; Zhong, L.; Matlik, K.; Porter, E. G.; Djomo, A. M.; Yau, I.; Soshnev, A. A.; Carroll, T. S.; Wen, D.; Hatten, M. E.; Garcia, B. A.; Allis, C. D.
10.1101/2023.09.29.560141 — molecular biology — Posted on 2023-09-29
129 mRNA N1-2'O-methylation by CMTR1 affects NVL2 mRNA splicing
Wolter, S.; Henning, T.; Wallerath, C.; Schlee-Guimaraes, T. M.; Kirchhoff, A.; Urban, C.; Piras, A.; Stukalov, A.; Juranek, S.; Engelke, M.; Boehm, V.; Gehring, N. H.; Hartmann, G.; Pichlmair, A.; Friedel, C. C.; Doelken, L.; Schlee, M.
10.1101/2023.09.28.560047 — molecular biology — Posted on 2023-09-29
131 Emergence of bluetongue virus serotype 3 in the Netherlands in September 2023
Holwerda, M.; Santman-Berends, I.; Harders, F.; Engelsma, M. Y.; Vloet, R.; Dijkstra, E.; van Gennip, R.; Mars, J.; Spierenburg, M.; Roos, L.; van den Brom, R.; van Rijn, P.
10.1101/2023.09.29.560138 — microbiology — Posted on 2023-09-29
132 TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites
Murphy, R. D.; Troublefield, C. A.; Miracle, J. S.; Young, L. E. A.; Brizzee, C. O.; Dhara, A.; Sun, R. C.; Vander Kooi, C. W.; Gentry, M. S.; Sinai, A. P.
10.1101/2023.09.29.560185 — microbiology — Posted on 2023-09-29
133 Discovery of essential kinetoplastid-insect adhesion proteins and their function in Leishmania-sand fly interactions
Yanase, R.; Pruzinova, K.; Rea, E.; Moreira-Leite, F.; Taniguchi, A.; Nonaka, S.; Sadlova, J.; Vojtkova, B.; Volf, P.; Sunter, J.
10.1101/2023.09.29.560188 — microbiology — Posted on 2023-09-29
135 Upc2-mediated mechanisms of azole resistance in Candida auris
Li, J.; Aubry, L.; Brandalise, D.; Coste, A. T.; Sanglard, D.; Lamoth, F.
10.1101/2023.09.29.560137 — microbiology — Posted on 2023-09-29
137 Toxin-mediated depletion of nicotinamide dinucleotides drives persister formation in a human pathogen
Jenal, U.; Santi, I.; Dias Teixeira, R.; Manfredi, P.; Spiess, D.; Mas, G.; Klotz, A.; Zamboni, N.; Hiller, S.
10.1101/2023.09.28.559889 — microbiology — Posted on 2023-09-29
139 Curcumin and turmeric extract inhibited SARS-CoV-2 pseudovirus cell entry and Spike mediated cell fusion
Septisetyani, E. P. P.; Lestari, D.; Paramitasari, K. A.; Prasetyaningrum, P. W.; Kastian, R. F.; Santoso, A.; Eriani, K.
10.1101/2023.09.28.560070 — pharmacology and toxicology — Posted on 2023-09-29
142 PROxAb Shuttle: A non-covalent plug-and-play platform for the rapid generation of tumor-targeting antibody-PROTAC conjugates
Schneider, H.; Jaeger, S.; Koenning, D.; Rasche, N.; Schroeter, C.; Elter, D.; Evers, A.; Lecomte, M.; Riccardi Sirtori, F.; Schwarz, D.; Wegener, A.; Hartung, I.; Rieker, M.
10.1101/2023.09.29.558399 — biochemistry — Posted on 2023-09-29
151 ecDNA amplification of MYC drives intratumor copy-number heterogeneity and adaptation to stress in PDAC
Malinova, A.; Schreyer, D.; Fiorini, E.; Pasini, D.; Bevere, M.; D'Agosto, S.; Andreani, S.; Lupo, F.; Veghini, L.; Grimaldi, S.; Pedron, S.; Nourse, C.; Salvia, R.; Malleo, G.; Ruzzenente, A.; Guglielmi, A.; Milella, M.; Lawlor, R. T.; Luchini, C.; Pilarsky, C.; Scarpa, A.; Tuveson, D.; Bailey, P.; Corbo, V.
10.1101/2023.09.27.559717 — cancer biology — Posted on 2023-09-29
154 Predicting rapid adaptation in time from adaptation in space: a 30-year field experiment in marine snails
Garcia Castillo, D. F.; Barton, N. H.; Faria, R.; Larsson, J.; Stankowski, S.; Butlin, R. K.; Johannesson, K.; Westram, A. M.
10.1101/2023.09.27.559715 — evolutionary biology — Posted on 2023-09-29
155 Differential reorganization of episodic and semantic memory systems in epilepsy-related mesiotemporal pathology
Cabalo, D. G.; Dekraker, J.; Royer, J.; Xie, K.; Tavakol, S.; Rodriguez - Cruces, R.; Bernasconi, A.; Bernasconi, N.; Weil, A.; Pana, R.; Frauscher, B.; Caciagli, L.; Jefferies, E.; Smallwood, J.; Bernhardt, B.
10.1101/2023.09.28.560002 — neuroscience — Posted on 2023-09-29
156 The neurovascular coupling in the attention during visual working memory
Zhang, H.; Hu, Y.; Li, Y.; Li, D.; Liu, H.; Li, X.; Song, Y.; Zhao, C.
10.1101/2023.09.28.559891 — neuroscience — Posted on 2023-09-29
158 Divergent Molecular Pathways for Toxicity of Selected Mutant C9ORF72-derived Dipeptide Repeats
Song, Y.; Tsai, M.; Wang, B.; Comassio, P.; Moreira, J.; Kriefall, N.; Morfini, G.; Brady, S.
10.1101/2023.09.28.558663 — neuroscience — Posted on 2023-09-29
159 Cell type-specific gene expression dynamics during human brain maturation
Steyn, C.; Mishi, R.; Fillmore, S.; Verhoog, M. B.; More, J.; Rohlwink, U. K.; Melvill, R.; Butler, J.; Enslin, J. M. N.; Jacobs, M.; Quinones, S.; Dulla, C. G.; Raimondo, J. V.; Figaji, A.; Hockman, D.
10.1101/2023.09.29.560114 — neuroscience — Posted on 2023-09-29
160 Erythropoietin restrains the inhibitory potential of interneurons in the mouse hippocampus
Curto, Y.; Carceller, H.; Klimczak, P.; Perez-Rando, M.; Wang, Q.; Grewe, K.; Rizzoli, S.; Geschwind, D.; Nave, K. A.; Teruel-Marti, V.; Singh, M.; Ehrenreich, H.; Nacher, J.
10.1101/2023.09.29.560076 — neuroscience — Posted on 2023-09-29
161 Visuomotor memory is not bound to visual motion
Warburton, M.; Campagnoli, C.; Mon-Williams, M.; Mushtaq, F.; Morehead, J. R.
10.1101/2023.09.27.559701 — neuroscience — Posted on 2023-09-29
164 HER2 Cellular Localization, Cell-Cell Contacts, and Cell Density Regulate Cancer Cell Plasticity in HER2+ Breast Cancer
Sameri, S.; Das, D.; Shahrivari, S.; Milosevic, V.; Sarhadi, S.; Koerkel-Qu, H.; Fisch, C.; Kokal, M.; Schletter, M.; Hahn, P. S.; Seider, L.; Schubel, M.; Michaelis, S.; Wegener, J.; Weber, F.; Hoffmann, M.; Werno, C.; Weidele, K.; Bruckmann, A.; Ostman, A.; Tamm, E. R.; Li, Y.; Klein, C. A.; Hosseini, H.
10.1101/2023.09.28.559965 — cancer biology — Posted on 2023-09-29
169 Contributions of hyperactive mutations in Mpro from SARS-CoV-2 to drug resistance
Flynn, J. M.; Duggan, S. N.; Shaqra, A. M.; Dovala, D.; Schiffer, C. A.; Bolon, D.
10.1101/2023.09.28.560010 — biochemistry — Posted on 2023-09-29
172 Clinal variation in drought response is consistent across life stages but not between native and non-native ranges
Nagy, D. U.; Thoma, A. E.; Al-Gharaibeh, M.; Callaway, R. M.; Flory, S. L.; Frazee, L. J.; Hartmann, M.; Hensen, I.; Jandova, K.; Khasa, D. P.; Lekberg, Y.; Robert, P. W.; Samartza, I.; Shah, M. A.; Sheng, M.; Slate, M.; Stein, C.; Tsunoda, T.; Rosche, C.
10.1101/2023.09.28.559709 — evolutionary biology — Posted on 2023-09-29
173 Thermal suppression of gametogenesis explains historical collapses in larval recruitment
Okamoto, D.; Spindel, N.; Collicutt, B.; Munstermann, M.; Karelitz, S.; Gimenez, I.; Rolheiser, K.; Cronmiller, E.; Foss, M.; Mahara, N.; Swezey, D.; Ferraro, R.; Rogers-Bennett, L.; Schroeter, S.
10.1101/2023.09.28.559919 — ecology — Posted on 2023-09-29
174 Single-cell transcription mapping of murine and human mammary organoids responses to female hormones
Ruiz-Ortiz, J.; Lewis, S. M.; Ciccone, M. F.; Chatterjee, D.; Henry, S.; Siepel, A.; Dos Santos, C. O.
10.1101/2023.09.28.559971 — developmental biology — Posted on 2023-09-29
175 Open top multi sample dual view light sheet microscope for live imaging of large multicellular systems
Moos, F.; Suppinger, S.; de Medeiros, G.; Oost, K.; Boni, A.; Remy, C.; Weevers, S.; Tsiairis, C. D.; Strnad, P.; Liberali, P.
10.1101/2023.09.28.559925 — developmental biology — Posted on 2023-09-29
182 Brain Glutathione and GABA+ levels in autistic children
Song, Y.; Hupfeld, K. E.; Davies-Jenkins, C. W.; Zöllner, H. J.; Murali-Manohar, S.; Abdul-Nashirudeen, M.; Crocetti, D.; Yedavalli, V.; Oeltzschner, G.; Alessi, N.; Batschelett, M. A.; Puts, N. A. J.; Mostofsky, S. H.; Edden, R. A. E.
10.1101/2023.09.28.559718 — neuroscience — Posted on 2023-09-29
183 A resource for probing influences of perinatal factors on neurodevelopment in 3-10-years-old Chinese children
Wang, Y.-S.; Su, X.-T.; Ke, L.; He, Q.-H.; Chang, D.; Nie, J.; Luo, X.; Chen, F.; Xu, J.; Zhang, C.; Zhang, S.; Zhang, S.; An, H.; Guo, R.; Yue, S.; Duan, W.; Jia, S.; Yang, S.; Yu, Y.; Zhao, Y.; Zhou, Y.; Chen, L.-Z.; Fan, X.-R.; Gao, P.; Lv, C.; Wu, Z.; Zhao, Y.; Quan, X.; Zhao, F.; Mu, Y.; Yan, Y.; Xu, W.; Liu, J.; Xing, L.; Chen, X.; Wu, X.; Zhao, L.; Huang, Z.; Ren, Y.; Hao, H.; Li, H.; Wang, J.; Dong, Q.; Chen, Y.; Huang, R.; Liu, S.; Wang, Y.; Dong, Q.; Zuo, X.-N.
10.1101/2023.09.28.560037 — neuroscience — Posted on 2023-09-29
184 Neural Evidence of Functional Compensation for Fluid Intelligence in Healthy Ageing
Knights, E.; Henson, R. N.; Morcom, A. M.; Mitchell, D. J.; Tsvetanov, K. A.
10.1101/2023.09.29.560099 — neuroscience — Posted on 2023-09-29
185 REM Sleep Measures and REM Vagal Activity Predict Extinction Recall in Trauma-Exposed Individuals
Yuksel, C.; Watford, L.; Muranaka, M.; Mendelsohn, A. K.; Oliver, K. I.; Daffre, C.; Lax, H.; Acosta, A.; Vidrin, A.; Martinez, U.; Lasko, N.; Pace-Schott, E. F.
10.1101/2023.09.28.560007 — neuroscience — Posted on 2023-09-29
187 A size principle for bistability in mouse spinal motoneurons
Harris-Warrick, R. M.; Pecchi, E.; Drouillas, B.; Brocard, F.; Bos, R.
10.1101/2023.09.29.559784 — neuroscience — Posted on 2023-09-29
191 An autophagy adaptor TRIAD3A promotes tau fibrillation by phase separation
Zhou, J.; Chuang, Y. a.; Redding-Ochoa, J.; Platero, A.; Barrett, A.; Troncoso, J.; Worley, P.; Zhang, W.
10.1101/2023.09.28.559893 — neuroscience — Posted on 2023-09-29
194 Pre-clinical Evaluation of Biomarkers for Early Detection of Nephrotoxicity Following Alpha-particle Radioligand Therapy
Li, M.; Robles-Planells, C.; Liu, D.; Graves, S. A.; Vasquez-Martinez, G.; Mayoral-Andrade, G.; Lee, D.; Rastogi, P.; Marks, B. M.; Sagastume, E. A.; Weiss, R. M.; Linn-Peirano, S. C.; Johnson, F. L.; Schultz, M. K.; Zepeda-Orozco, D.
10.1101/2023.09.27.559789 — pharmacology and toxicology — Posted on 2023-09-29
195 Prenatal Arsenite Exposure Alters Maternal Cardiac Remodeling During Late Pregnancy
Taube, N.; Kabir, R.; Ebenebe, O. V.; Garbus, H.; Alam El Din, S.-M.; Illingworth, E.; Fitch, M.; Wang, N.; Kohr, M. J.
10.1101/2023.09.28.559986 — pharmacology and toxicology — Posted on 2023-09-29
196 The Physical Biology of Nucleolus Disassembly
Pham, A. T.; Mani, M.; Wang, X. A.; Vafabakhsh, R.
10.1101/2023.09.27.559731 — biophysics — Posted on 2023-09-29
205 Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease
Alugubelli, Y. R.; Xiao, J.; Khatua, K.; Kumar, S.; Ma, Y.; Ma, X.; Vulupala, V. R.; Atla, S.; Blankenship, L.; Coleman, D.; Neuman, B. W.; Liu, W.; Xu, S.
10.1101/2023.09.29.560163 — biochemistry — Posted on 2023-09-29
214 Phage-bacteria dynamics during the first years of life revealed by trans-kingdom marker gene analysis
Tisza, M. J.; Lloyd, R. E.; Hoffman, K. L.; Smith, D. P.; Rewers, M.; the TEDDY Study Group, ; Cregeen, S. J. J.; Petrosino, J. F.
10.1101/2023.09.28.559994 — microbiology — Posted on 2023-09-29
215 Identification of host factor for Rift valley fever Phlebovirus
Balaraman, V.; Indran, S.; Meekins, D.; Jakkula, L. U. M. R.; Liu, H.; Hays, M.; Li, Y.; Souza Neto, J.; Gaudreault, N. N.; Hardwidge, P.; Wilson, W. C.; Weber, F.; Richt, J. A.
10.1101/2023.09.28.559935 — microbiology — Posted on 2023-09-29
220 Test-retest reliability of MEG functional brain connectivity related to language processing
Ala-Salomäki, H.; van Vliet, M.; Kujala, J.; Roine, T.; Liljeström, M.; Salmelin, R.
10.1101/2023.09.27.559879 — neuroscience — Posted on 2023-09-29
221 GENERATION OF FUNCTIONAL NEURONS FROM ADULT HUMAN MUCOSAL OLFACTORY ENSHEATHING GLIA BY DIRECT LINEAGE CONVERSION
Portela-Lomba, M.; Simon, D.; Callejo-Mostoles, M.; de la Fuente, G.; Fernandez de Sevilla, D.; Garcia-Escudero, V.; Moreno-Flores, M. T.; Sierra, J.
10.1101/2023.09.28.559940 — neuroscience — Posted on 2023-09-29
223 Personalised Regional Modelling Predicts Tau Progression in the Human Brain
Chaggar, P.; Vogel, J. W.; Pichet-Binette, A.; Thompson, T. B.; Strandberg, O. B.; Stomrud, E.; Mattsson-Carlgren, N.; Karlsson, L.; Jbabdi, S.; Magon, S.; Klein, G.; Alzheimer's Disease Neuroimaging Initiative, ; Hansson, O.; Goriely, A.
10.1101/2023.09.28.559911 — neuroscience — Posted on 2023-09-29
224 Mitochondrial CISD1 is a downstream target that mediates PINK1 and Parkin loss-of-function phenotypes
Bitar, S.; Baumann, T.; Weber, C.; Abusaada, M.; Rojas-Charry, L.; Ziegler, P.; Schettgen, T.; Randerath, I. E.; Venkataramani, V.; Michalke, B.; Arena, G.; Krueger, R.; Zhang, L.; Methner, A.
10.1101/2023.09.28.559909 — neuroscience — Posted on 2023-09-29
226 Taxonomy for human social perception
Santavirta, S.; Malen, T.; Erdemli, A.; Nummenmaa, L.
10.1101/2023.09.28.559888 — neuroscience — Posted on 2023-09-29
230 Forward Genetic Stomatal CO2 Response Screen in Grass Brachypodium distachyon Reveals Central Function of a MAP Kinase in Early Stomatal CO2 Signal Transduction
Lopez, B. N. K.; Ceciliato, P. H. O.; Rangel, F.; Salem, E.; Kernig, K.; Takahashi, Y.; Chow, K.; Zhang, L.; Sidhom, M.; Seitz, C.; Sibout, R.; Laudencia, D.; Woods, D. P.; McCammon, J. A.; Vogel, J.; Schroeder, J. I.
10.1101/2023.09.28.559842 — plant biology — Posted on 2023-09-29
231 Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis
Ersoy, U.; Kanakis, I.; Alameddine, M.; Pedraza Vazquez, G.; E. Ozanne, S.; Peffers, M. J.; Jackson, M. J.; Goljanek-Whysall, K.; Vasilaki, A.
10.1101/2023.09.27.559536 — physiology — Posted on 2023-09-29
232 Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice
Guo, Z.-F.; Tongmuang, N.; Li, C.; Zhang, C.; Hu, L.; Capreri, C.; Zuo, M.-X.; Summer, R.; Sun, J.
10.1101/2023.09.27.559864 — physiology — Posted on 2023-09-29
234 Improvisation and Live Accompaniment Increase Motor Response and Reward During a Music Playing Task
Palumbo, A.; Groves, K.; Vidal, E. L. M.; Turry, A.; Raghavan, P.; Schambra, H.; Voelbel, G.; Ripolles, P.
10.1101/2023.09.28.559982 — physiology — Posted on 2023-09-29
239 Longitudinal and multimodal auditing of tumor adaptation to CDK4/6 inhibitors in HR+ metastatic breast cancers
Creason, A. L.; Egger, J.; Watson, C.; Sivagnanam, S.; Chin, K.; MacPherson, K.; Lin, J.-R.; Chen, Y.-A.; Johnson, B. E.; Feiler, H. S.; Galipeau, D.; Navin, N. E.; Demir, E.; Chang, Y. H.; Corless, C. L.; Mitri, Z. I.; Thomas, G.; Sorger, P. K.; Adey, A. C.; Coussens, L. M.; Gray, J. W.; Mills, G. B.; Goecks, J.
10.1101/2023.09.27.557464 — cancer biology — Posted on 2023-09-29
244 Network-based integrative multi-omics approach reveals biosignatures specific to COVID-19 disease phases.
Agamah, F. E.; Ederveen, T. H. A.; Skelton, M.; Martin, D. P.; Chimusa, E. R.; 't Hoen, P. A. C.
10.1101/2023.09.29.560110 — bioinformatics — Posted on 2023-09-29
247 Deepurify: a multi-modal deep language model to remove contamination from metagenome-assembled genomes
ZOU, B.; Wang, J.; Ding, Y.; Zhang, Z.; Yufen, H.; Fang, X.; Cheung, K. C.; See, S.; Zhang, L.
10.1101/2023.09.27.559668 — genomics — Posted on 2023-09-29
250 Timing specific parental effects of ocean warming in a coral reef fish
Bonzi, L. C.; Spinks, R. K.; Donelson, J. M.; Munday, P. L.; Ravasi, T.; Schunter, C.
10.1101/2023.09.27.559693 — evolutionary biology — Posted on 2023-09-29
255 Pre-zygotic mate selection affects progeny fitness and is only partially correlated with the expression of NaS-like RNases
Baraniecka, P.; Seibt, W.; Groten, K.; Kessler, D.; McGale, E.; Gase, K.; Baldwin, I. T.; Pannell, J.
10.1101/2023.09.27.559675 — ecology — Posted on 2023-09-29
258 Cognitive tasks, anatomical MRI, and functional MRI data evaluating the construct of self-regulation
Bissett, P. G.; Eisenberg, I. W.; Shim, S.; Rios, J. A. H.; Jones, H. M.; Hagen, M. P.; Enkavi, A. Z.; Li, J. K.; Mumford, J. A.; MacKinnon, D. P.; Marsch, L. A.; Poldrack, R.
10.1101/2023.09.27.559869 — neuroscience — Posted on 2023-09-29
261 Mechanical imbalance between normal and cancer cells drives epithelial defence against cancer
Gupta, P.; Kayal, S.; Pothapragada, S. P.; Senapati, H. K.; Devendran, P.; Bi, D.; Das, T.
10.1101/2023.09.27.559723 — biophysics — Posted on 2023-09-29
262 Networked proteins redundantly interact with VAP27 and RABG3 to regulate membrane tethering at the vacuole and beyond
Kaiser, S.; Mehlhorn, D.; Ramirez Miranda, P.; Ries, F.; Sommer, F.; Schroda, M.; Schumacher, K.; Willmund, F.; Grefen, C.; Scheuring, D.
10.1101/2023.09.29.560113 — cell biology — Posted on 2023-09-29
263 TLNRD1 is a CCM complex component and regulates endothelial barrier integrity
Ball, N. J.; Ghimire, S.; Follain, G.; Pajari, A. O.; Vaitkeviciute, M.; Cowell, A. R.; Berki, B.; Ivaska, J.; Paatero, I.; Goult, B. T.; Jacquemet, G.
10.1101/2023.09.29.559344 — cell biology — Posted on 2023-09-29
265 NEW INSIGHTS INTO THE HEPATIC IRON PHENOTYPE OF BMP6 KNOCKOUT MICE
BESSON, C.; WILLEMETZ, A.; LATOUR, C.; ROBERT, L.; COPPIN, H.; ROTH, M.-P.; CANONNE-HERGAUX, F.
10.1101/2023.09.28.559941 — pathology — Posted on 2023-09-29
266 Lysine 36 of Drosophila histone H3.3 supports adult longevity
Brown, J. C.; McMichael, B. D.; Vandadi, V.; Mukherjee, A.; Salzler, H. R.; Matera, A. G.
10.1101/2023.09.28.559962 — genetics — Posted on 2023-09-29
269 Hypothalamic representation of the imminence of predator threat detected by the vomeronasal organ in mice
Nguyen, Q. A. T.; Rocha, A.; Yamashita, Y.; Chhor, R.; Stadler, C.; Pontrello, C.; Haga-Yamanaka, S.
10.1101/2023.09.27.559655 — neuroscience — Posted on 2023-09-29
271 MultipleXed Population Selection and Enrichment single nucleus RNA sequencing (XPoSE-seq) enables sample identity retention during transcriptional profiling of rare populations
Savell, K. E.; Madangopal, R.; Saravanan, P.; Palaganas, R. G.; Woods, K. D.; Thompson, D. J.; Drake, O. R.; Brenner, M. B.; Weber, S. J.; Van Leer, E.; Choi, J. H.; Martin, T. L.; Martin, J. C.; Steinberg, M. K.; Austin, J. W.; Charendoff, C. I.; Hope, B. T.
10.1101/2023.09.27.559834 — neuroscience — Posted on 2023-09-29
274 Tracking genome evolution in single cell clones reveals the rates and features of copy number alterations generated by ongoing chromosomal instability in cancer.
McClelland, S. E.; Guscott, M. A.; Gomez-Peregrina, D.; Andersen, A.; Soliman, T.; Vidal-Horrach, C.; Bakker, B.; Spierings, D. C. J.; Wardenaar, R.; Foijer, F.; Serrano, C.; Schwarz, R.
10.1101/2023.09.27.559836 — cancer biology — Posted on 2023-09-29
281 The genetic architecture of the pepper metabolome provides insights into the regulation of capsianoside biosynthesis
Nauen, J.; Tripodi, P.; Wendenberg, R.; Tringovska, I.; Nankar, A. N.; Stoeva, V.; Pasev, G.; Klemmer, A.; Todorova, V.; Bulut, M.; Tikunov, Y.; Bovy, A.; Gechev, T.; Kostova, D.; Alseekh, S.; Fernie, A. R.
10.1101/2023.09.27.559835 — genetics — Posted on 2023-09-29
285 Phylogenomics reveals the demography of reverse colonization in a rail species
Aoki, D.; Senzaki, M.; Ando, H.; Odaya, Y.; Heim, W.; Kitazawa, M.; Tom, W.; Trense, D.; Bastardot, M.; Fukuda, A.; Takahashi, M.; Kondo, N.
10.1101/2023.09.27.559751 — evolutionary biology — Posted on 2023-09-29
289 Immune modulation of innate and adaptive responses restores immune surveillance and establishes anti-tumor immunological memory
Alvero, A. B.; Fox, A.; Madina, B.; Krady, M.; Gogoi, R.; Chehade, H.; Nakaar, V.; Almassian, B.; Yarovinsky, T. O.; Rutherford, T.; Mor, G.
10.1101/2023.09.27.559828 — immunology — Posted on 2023-09-29
290 Replenishing Age-Related Decline of IRAK-M Expression in Retinal Pigment Epithelium Attenuates Outer Retinal Degeneration
Liu, J.; Copland, D. A.; Clare, A. J.; Gorski, M.; Richards, B. T.; Scott, L.; Theodoropoulou, S.; Greferath, U.; Cox, K.; Bell, O. H.; Ou, K.; Powell, J. L. B.; Wu, J.; Martinez Robles, L.; Li, Y.; Nicholson, L. B.; Coffey, P. J.; Fletcher, E. L.; Guymer, R.; Radeke, M. J.; Heid, I. M.; Hageman, G. S.; Chan, Y. K.; Dick, A. D.
10.1101/2023.09.27.559733 — immunology — Posted on 2023-09-29
294 Central pore-opening structure and gating of the mechanosensitive PIEZO1 channel
Liu, S.; Yang, X.; Chen, X.; Zhang, X.; Jiang, J.; Wang, L.; Yuan, J.; Liu, W.; Zhou, H.; Wu, K.; Tian, B.; Li, X.; Xiao, B.
10.1101/2023.09.28.559900 — neuroscience — Posted on 2023-09-29
295 4R-Tau seeding activity unravels molecular subtypes in patients with Progressive Supranuclear Palsy
Martinez-Valbuena, I.; Lee, S.; Santamaria, E.; Irigoyen, J. F.; Forrest, S.; Li, J.; Tanaka, H.; Couto, B.; Reyes, N. G.; Qamar, H.; Karakani, A. M.; Kim, A.; Senkevich, K.; Rogaeva, E.; Fox, S. H.; Tartaglia, C.; Visanji, N. P.; Andrews, T.; Lang, A. E.; Kovacs, G. G.
10.1101/2023.09.28.559953 — neuroscience — Posted on 2023-09-29
297 Int&in: a machine learning-based web server for split site identification in inteins
Di Ventura, B.; Schmitz, M.; Ballestin Ballestin, J.; Liang, J.; Tomas, F.; Freist, L.; Voigt, K.; Öztürk, M. A.
10.1101/2023.09.27.559783 — synthetic biology — Posted on 2023-09-29
298 A telomere-to-telomere genome assembly of Zhonghuang 13, a widely-grown soybean variety from the original center of Glycine max
Zhang, A.; Kong, T.; Sun, B.; Qiu, S.; Guo, J.; Ruan, S.; Guo, Y.; Guo, J.; Zhang, Z.; Liu, Y.; Hu, Z.; Jiang, T.; Liu, Y.; Cao, S.; Sun, S.; Wu, T.; Hong, H.; Jiang, B.; Yang, M.; Yao, X.; Hu, Y.; Liu, B.; Han, T.; Wang, Y.
10.1101/2023.09.27.559666 — plant biology — Posted on 2023-09-29
299 Anti-prion drugs do not improve survival in knock-in models of inherited prion disease
Walsh, D.; Rees, J.; Mehra, S.; Bourkas, M.; Kaczmarczyk, L.; Stuart, E.; Jackson, W.; Watts, J.; Supattapone, S.
10.1101/2023.09.28.559951 — pharmacology and toxicology — Posted on 2023-09-29
300 Neuroprotective Mechanism of Ribisin A on H 2 O 2 -induced PC12 cell injury model
Zhang, X.; Bao, M.; Zhang, J.; Zhu, L.; Wang, D.; Liu, X.; Xu, L.; Luan, L.; Liu, Y.; Liu, Y.
10.1101/2023.09.27.559840 — pharmacology and toxicology — Posted on 2023-09-29
304 imply: improving cell-type deconvolution accuracy using personalized reference profiles
Meng, G.; Pan, Y.; Tang, W.; Zhang, L.; Cui, Y.; Schumacher, F.; Wang, M.; Wang, R.; He, S.; Krischer, J.; Li, Q.; Feng, H.
10.1101/2023.09.27.559579 — bioinformatics — Posted on 2023-09-29
309 SASH1 interacts with TNKS2 and promotes human melanocyte stem cell maintenance
Lambert, K. A.; Clements, C. M.; Mukherjee, N.; Pacheco, T. R.; Shellman, S. X.; Henen, M. A.; Vogeli, B.; Goldstein, N. B.; Birlea, S.; Hintzsche, J.; Tan, A.-C.; Zhao, R.; Norris, D. A.; Robinson, W. A.; Wang, Y.; VanTreeck, J. G.; Shellman, Y. G.
10.1101/2023.09.26.559624 — cell biology — Posted on 2023-09-29
310 Identification of a link between splicing and endoplasmic reticulum proteostasis
Farhan, H.; Zahoor, M.; Dong, Y.; Preussner, M.; Shameen Alam, S.; Hajdu, R.; Reiterer, V.; Geley, S.; Cormier-Daire, V.; Heyd, F.; Jerome-Majewska, L. A.
10.1101/2023.09.28.559974 — cell biology — Posted on 2023-09-29
312 An adapted method for Cas9-mediated editing reveals the species-specific role of β-glucoside utilization driving competition between Klebsiella species
Strowig, T.; de Hoog-Almasi, E.; Knischewski, N.; Osbelt, L.; Muthukumarasamy, U.; El Mouali, Y.; Vialetto, E.; Beisel, C.
10.1101/2023.09.27.559776 — microbiology — Posted on 2023-09-29
313 Phylogenomics and ancestral reconstruction of Korarchaeota reveals genomic adaptation to habitat switching
Tahon, G.; Köstlbacher, S.; Pelve, E. A.; Baker, B. J.; Saw, J. H.; Eme, L.; Tamarit, D.; Schön, M. E.; Ettema, T. J.
10.1101/2023.09.28.559970 — microbiology — Posted on 2023-09-29
314 C4 induces pathological synaptic loss by impairing AMPAR trafficking.
Phadke, R. A.; Kruzich, E.; Fournier, L. A.; Brack, A.; Sha, M.; Picard, I.; Johnson, C.; Stroumbakis, D.; Salgado, M.; Liu, Y. Y.; Cruz-Martin, A.
10.1101/2023.09.09.556388 — neuroscience — Posted on 2023-09-29
315 The FW2.2/CNR protein regulates cell-to-cell communication in tomato by modulating callose deposition at plasmodesmata
Beauchet, A.; Bollier, N.; Grison, M.; Rofidal, V.; Gevaudant, F.; Bayer, E. M. F.; Gonzalez, N.; Chevalier, C.
10.1101/2023.09.27.559775 — plant biology — Posted on 2023-09-29
316 Emergence of ion-channel mediated electrical oscillations in E. coli biofilms
Akabuogu, E. U.; Martorelli, V.; Krasovec, R.; Roberts, I. S.; Waigh, T. A.
10.1101/2022.11.09.515771 — biophysics — Posted on 2023-09-29
317 Missing view completion for multi-timepoints omics data via representation disentanglement and temporal knowledge transfer
Han, S.; Yu, S.; Shi, M.; Harada, M.; Ge, J.; Lin, J.; Prehn, C.; Petrera, A.; Li, Y.; Sam, F.; Matullo, G.; Adamski, J.; Suhre, K.; Gieger, C.; Hauck, S. M.; Herder, C.; Roden, M.; Casale, F. P.; Cai, N.; Peters, A.; Wang-Sattler, R.
10.1101/2023.09.26.559302 — bioinformatics — Posted on 2023-09-29
319 Monitoring lasting changes to brain tissue integrity through mechanical properties following adolescent exercise intervention in a rat model of Fetal Alcohol Spectrum Disorders
Milbocker, K. A.; Williams, L. T.; Caban-Rivera, D. A.; Smith, I. F.; Kurtz, S.; McGarry, M. D.; Wattrisse, B.; Van Houten, E. E.; Johnson, C. L.; Klintsova, A. Y.
10.1101/2023.09.26.559571 — bioengineering — Posted on 2023-09-29
320 A complex and dynamic redox network regulating oxygen reduction at photosystem I
Krieger-Liszkay, A.; Hani, U.; Naranjo, B.; Shimakawa, G.; Vanacker, H.; Espinasse, C.; Setif, P.; Rintamäki, E.; Issakidis-Bourguet, E.
10.1101/2023.09.28.559979 — biochemistry — Posted on 2023-09-29
322 In vitro pigmentation of human iPSC-derived retinal pigment epithelium cells does not indicate their quality for cell transplantation
Nakai-Futatsugi, Y.; Jin, J.; Ogawa, T.; Sakai, N.; Maeda, A.; Hironaka, K.-i.; Fukuda, M.; Danno, H.; Tanaka, Y.; Hori, S.; Shiroguchi, K.; Takahashi, M.
10.1101/2023.09.29.560095 — cell biology — Posted on 2023-09-29
324 The impact of HTLV-1 expression on the 3D structure and expression of host chromatin
Yaguchi, H.; Melamed, A.; Ramanayake, S.; Kiik, H.; Witkover, A.; Bangham, C. R. M.
10.1101/2023.09.28.559884 — microbiology — Posted on 2023-09-29
327 Endothelial cell-derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate pathological cardiac remodeling via intercellular crosstalk
Keles, M.; Grein, S.; Froese, N.; Wirth, D.; Trogisch, F. A.; Wardman, R.; Hemanna, S.; Weinzierl, N.; Reiners-Koch, P.-S.; Uhlig, S.; Lomada, S.; Dittrich, G. M.; Szaroszyk, M.; Haustein, R.; Hegermann, J.; Martin Garrido, A.; Bauersachs, J.; Frank, D.; Frey, N.; Bieback, K.; Cordero, J.; Dobreva, G.; Wieland, T.; Heineke, J.
10.1101/2022.09.19.508486 — systems biology — Posted on 2023-09-28
328 Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice
Lee, J.; Wellenstein, K.; Rahnavard, A.; Nelson, A. T.; Holter, M.; Cummings, B. P.; Yeliseyev, V.; Castoldi, A.; Clish, C. B.; Bry, L.; Siegel, D.; Kahn, B. B.
10.1101/2023.09.28.558803 — physiology — Posted on 2023-09-29
329 Modeling Thick Filament Activation Suggests a Molecular Basis for Force Depression
Liu, S.; Marang, C.; Woodward, M.; Joumaa, V.; Leonard, T.; Scott, B.; Debold, E.; Herzog, W.; Walcott, S.
10.1101/2023.09.27.559764 — biophysics — Posted on 2023-09-29
331 SARS-CoV-2 NSP14 governs mutational instability and assists in making new SARS-CoV-2 variants
Hassan, S. S.; Bhattacharya, T.; Nawn, D.; Jha, I.; Basu, P.; Redwan, E. M.; Lundstrom, K.; Barh, D.; Andrade, B.; Tambuwala, M. M.; Aljabali, A. A.; Hromic-Jahjefendic, A.; Baetas-da-Cruz, W.; Uversky, V. N.
10.1101/2023.09.28.559966 — bioinformatics — Posted on 2023-09-29
336 Microinterfaces in bicontinuous hydrogelsguide rapid 3D cell migration
Xu, K. L.; Caprio, N. d.; Fallahi, H.; Dehghany, M.; Davidson, M. D.; Cheung, B. C. H.; Laforest, L.; Wu, M.; Shenoy, V.; Han, L.; Mauck, R.; Burdick, J.
10.1101/2023.09.28.559609 — bioengineering — Posted on 2023-09-29
341 Plasma of COVID-19 patients does not alter electrical resistance of human endothelial blood-brain barrier in vitro.
Pociute, A.; Kriauciunaite, K.; Kausyle, A.; Zablockiene, B.; Alcauskas, T.; Jelinskaite, A.; Rudenaite, A.; Jancioriene, L.; Rocka, S.; Verkhratsky, A.; Pivoriunas, A.
10.1101/2023.09.28.559927 — neuroscience — Posted on 2023-09-29
342 Dissolving microneedle array patches containing mesoporous silica nanoparticles of different pore sizes as a tunable sustained release platform
Paris, J. L.; Vora, L. K.; Perez-Moreno, A. M.; Naser, Y. A.; Anjani, Q. K.; Canas, J. A.; Torres, M. J.; Mayorga, C.; Donnelly, R. F.
10.1101/2023.09.27.559712 — pharmacology and toxicology — Posted on 2023-09-29
345 Fluorogenic Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide Activated SIRT7
Bolding, J. E.; Nielsen, A. L.; Jensen, I.; Hansen, T. N.; Ryberg, L. A.; Jameson, S. T.; Harris, P.; Peters, G. H.; Denu, J.; Rogers, J. M.; Olsen, C. A.
10.1101/2023.06.16.545261 — biochemistry — Posted on 2023-09-29
349 Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling
Dong, Y.; Johns, B. A.; Ruan, L.; Zeineldin, M.; Liu, A.; Raychaudhuri, S.; Chiu, I.; Zhu, J.; Smith, B.; Zhao, N.; Searson, P.; Watanabe, S.; Donowitz, M.; Larman, T. C.; Li, R.
10.1101/2023.09.28.560060 — cell biology — Posted on 2023-09-29
350 SETD2 maintains nuclear lamina stability to safeguard the genome
Khan, A.; Metts, J. M.; Collins, L. C.; Mills, C. A.; Li, K.; Brademeyer, A. L.; Bowman, B. M.; Major, M. B.; Aube, J.; Herring, L. E.; Davis, I. J.; Strahl, B. D.
10.1101/2023.09.28.560032 — cell biology — Posted on 2023-09-29
351 Bidirectional interaction between Protocadherin 8 and transcription factor Dbx1 regulates cerebral cortex development
Cwetsch, A. W.; Gilabert Juan, J.; Ferreira, S.; Moreau, M. X.; Saillour, Y.; Delberghe, E.; Gonzalez-Martinez, J.; Borello, U.; Causeret, F.; Pierani, A.
10.1101/2023.09.28.559903 — neuroscience — Posted on 2023-09-29
356 Sequence characterization of T, Bip, and Phbw demonstrates the role of MYB-bHLH-WD40 complexes and temperature in common bean seed color pattern formation
Parker, T.; Bolt, T.; Williams, T.; Penmetsa, R. V.; Mulube, M.; Palkovic, A.; Jochua, C. N.; Rubio Wilhelmi, M. d. M.; Lo, S.; Bornhorst, G.; Tian, L.; Kamfwa, K.; Hokin, S.; Farmer, A.; Diepenbrock, C. H.; Gepts, P.
10.1101/2023.09.23.559151 — plant biology — Posted on 2023-09-29
362 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α-primase
Mullins, E. A.; Salay, L. E.; Durie, C. L.; Bradley, N. P.; Jackman, J. E.; Ohi, M. D.; Chazin, W. J.; Eichman, B. F.
10.1101/2023.03.16.533013 — biochemistry — Posted on 2023-09-28
365 Fishing for a reelGene: evaluating gene models with evolution and machine learning
Schulz, A. J.; Zhai, J.; AuBuchon-Elder, T.; El-Walid, M.; Ferebee, T. H.; Gilmore, E. H.; Hufford, M. B.; Johnson, L. C.; Kellogg, E.; La, T.; Long, E.; Miller, Z. R.; Romay, C.; Seetharam, A. S.; Stitzer, M. C.; Wrightsman, T.; Buckler, E. S.; Monier, B.; Hsu, S.-K.
10.1101/2023.09.19.558246 — genomics — Posted on 2023-09-29
366 A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats
de Jong, T. V.; Pan, Y.; Rastas, P.; Munro, D.; Tutaj, M.; Akil, H.; Benner, C.; Chen, D.; Chitre, A. S.; Chow, W.; Colonna, V.; Dalgard, C. L.; Demos, W. M.; Doris, P. A.; Garrison, E.; Geurts, A. M.; Gunturkun, H. M.; Guryev, V.; Hourlier, T.; Howe, K.; Huang, J.; Kalbfleisch, T.; Kim, P.; Li, L.; Mahaffey, S.; Martin, F. J.; Mohammadi, P.; Ozel, A. B.; Polesskaya, O.; Pravenec, M.; Prins, P.; Sebat, J.; Smith, J. R.; Solberg Woods, L. C.; Tabakoff, B.; Tracey, A.; Uliano-Silva, M.; Villani, F.; Wang, H.; Sharp, B. M.; Telese, F.; Jiang, Z.; Saba, L.; Wang, X.; Murphy, T. D.; Palmer, A. A.;
10.1101/2023.04.13.536694 — genomics — Posted on 2023-09-29
367 Mapping the genetic evolutionary timeline of human neural and cognitive traits
Libedinsky, I.; Wei, Y.; de Leeuw, C.; Rilling, J.; Posthuma, D.; van den Heuvel, M.
10.1101/2023.02.05.525539 — genetics — Posted on 2023-09-28
368 Salmonella actively modulates TFEB in murine macrophages in a growth-phase and time-dependent manner
Inpanathan, S.; Ospina-Escobar, E.; Li, V. C.; Adamji, Z.; Lackraj, T.; Cho, Y. H.; Porco, N.; Choy, C. H.; McPhee, J. B.; Botelho, R. J.
10.1101/2022.12.03.518968 — cell biology — Posted on 2023-09-28
369 Autophagy initiation triggers p150Glued-AP-2β interaction on the lysosomes to facilitate their transport.
Tempes, A.; Bogusz, K.; Brzozowska, A.; Weslawski, J.; Macias, M.; Tkaczyk, O.; Lew, A.; Calka-Kresa, M.; Bernas, T.; Szczepankiewicz, A. A.; Orzol, K.; Mlostek, M.; Kumari, S.; Bakun, M.; Rubel, T.; Malik, A. R.; Jaworski, J.
10.1101/2022.06.19.496704 — cell biology — Posted on 2023-09-28
370 Temporal Dynamics and Stoichiometry in Notch Signaling - from Notch Synaptic Complex Formation to NICD Nuclear Entry
Tveriakhina, L.; Scanavachi, G.; Egan, E. D.; Correia, R. B. D. C.; Martin, A. P.; Rogers, J. M.; Yodh, J. S.; Aster, J. C.; Kirchhausen, T.; Blacklow, S. C.
10.1101/2023.09.27.559780 — cell biology — Posted on 2023-09-28
371 Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach
Uryu, K.; Soplop, N.; Sheahan, T. P.; Catanese, M.-T.; Huynh, C.; Pena, J.; Boudreau, N.; Matei, I.; Kenific, C.; Hashimoto, A.; Hoshino, A.; Rice, C. M.; Lyden, D.
10.1101/2023.09.28.559906 — cell biology — Posted on 2023-09-28
372 AMPK Regulates Phagophore-to-Autophagosome Maturation
Schmidt, J. C.; Barnaba, C.; Broadbent, D. G.; Perez, G. I.
10.1101/2023.09.28.559981 — cell biology — Posted on 2023-09-28
373 Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis
Homan, K.; Onodera, T.; Hanamatsu, H.; Furukawa, J.-i.; Momma, D.; Matsuoka, M.; Iwasaki, N.
10.1101/2023.09.28.560052 — cell biology — Posted on 2023-09-29
374 An amphipathic helix drives interaction of Fibrillins with plastoglobule lipid droplets
Shivaiah, K.-K.; Boren, D. M.; Herrera-Tequia, A.; Vermaas, J.; Lundquist, P. K.
10.1101/2023.09.28.559984 — cell biology — Posted on 2023-09-29
378 Temporal dynamics of neural adaptation across human visual cortex
Brands, A. M.; Devore, S.; Devinsky, O.; Doyle, W.; Flinker, A.; Friedman, D.; Dugan, P.; Winawer, J.; Groen, I. I. A.
10.1101/2023.09.13.557378 — neuroscience — Posted on 2023-09-28
382 MicroRNAs are necessary for the emergence of Purkinje cell identity
Zolboot, N.; Xiao, Y.; Du, J. X.; Ghanem, M. M.; Choi, S. Y.; Junn, M. J.; Zampa, F.; Huang, Z.; MacRae, I. J.; Lippi, G.
10.1101/2023.09.28.560023 — neuroscience — Posted on 2023-09-28
383 Cadherins orchestrate specific patterns of perisomatic inhibition onto distinct pyramidal cell populations
Jezequel, J.; Condomitti, G.; Kroon, T.; Hamid, F.; Sanalidou, S.; Garces, T.; Maeso, P.; Balia, M.; Rico, B.
10.1101/2023.09.28.559922 — neuroscience — Posted on 2023-09-28
384 Single-Soma Deep RNA sequencing of Human DRG Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation
Yu, H.; Usoskin, D.; Nagi, S. S.; Hu, Y.; Kupari, J.; Bouchatta, O.; Cranfill, S. L.; Gautam, M.; Su, Y.; Lu, Y.; Wymer, J.; Glanz, M.; Albrecht, P.; Song, H.; Ming, G.-L.; Prouty, S.; Seykora, J.; Wu, H.; Ma, M.; Rice, F. L.; Olausson, H.; Ernfors, P.; Luo, W.
10.1101/2023.03.17.533207 — neuroscience — Posted on 2023-09-28
390 The interplay between molecular assembly and phase separation
Bartolucci, G.; Haugerud, I. S.; Michaels, T. C. T.; Weber, C. A.
10.1101/2023.04.18.537072 — biophysics — Posted on 2023-09-28
391 Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings
Sasse, A.; Ng, B.; Spiro, A.; Tasaki, S.; Bennett, D.; Gaiteri, C.; De Jager, P. L.; Chikina, M.; Mostafavi, S.
10.1101/2023.03.16.532969 — bioinformatics — Posted on 2023-09-28
394 Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
Chen, M.; Ren, X.; Nguyen, T. N.; Khuu, G.; Cook, A. S. I.; Lazarou, M.; Hurley, J. H.
10.1101/2023.06.01.543278 — biochemistry — Posted on 2023-09-28
395 Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate
Rouleau, F. D.; Dube, A. K.; Gagnon-Arsenault, I.; Dibyachintan, S.; Pageau, A.; Despres, P. C.; Lagüe, P.; Landry, C. R.
10.1101/2023.09.27.559786 — biochemistry — Posted on 2023-09-28
396 The genomic landscape of metallic color variation in ground beetles
Weng, Y.-M.; Kavanaugh, D. H.; Rubio-Perez, B.; Salman, J.; Kats, M. A.; Schoville, S. D.
10.1101/2023.09.25.559374 — evolutionary biology — Posted on 2023-09-28
397 Whole-genome sequencing confirms multiple species of Galapagos giant tortoises
Gaughran, S. J.; Gray, R.; Jones, M.; Fusco, N.; Ochoa, A.; Miller, J. M.; Poulakakis, N.; de Queiroz, K.; Caccone, A.; Jensen, E. L.
10.1101/2023.04.05.535692 — evolutionary biology — Posted on 2023-09-28
404 Host metabolic pathways essential for malaria and related hemoparasites in the infection of nucleated cells
Maurizio, M.; Masad, M.; Woods, K.; Caldelari, R.; Doench, J. G.; Naguleswaran, A.; Joly, D.; Fernandez, M. G.; Zemp, J.; Borteele, M.; Hatzimanikatis, V.; Heussler, V.; Rottenberg, S.; Olias, P.
10.1101/2023.09.27.559824 — microbiology — Posted on 2023-09-28
406 Heat n Beat: A universal high-throughput end-to-end proteomics sample processing platform in under an hour
Xavier, D.; Lucas, N.; Williams, S. G.; Koh, J. M. S.; Ashman, K.; Loudon, C.; Reddel, R.; Hains, P. G.; Robinson, P. J.
10.1101/2023.09.27.559846 — biochemistry — Posted on 2023-09-28
407 Structural pathway for class III PI 3-kinase activation by the myristoylated GTP-binding pseudokinase VPS15
Cook, A. S. I.; Chen, M. H.; Ren, X.; Rao, S.; Garcia, S. N.; Claveras Cabezudo, A.; Iavarone, A. T.; Hummer, G.; Hurley, J. H.
10.1101/2023.09.28.559894 — biochemistry — Posted on 2023-09-28
409 Multiscale chromatin dynamics and high entropy in plant iPSC cultures
Rutowicz, K.; Luethi, J.; de Groot, R.; Holtackers, R.; Yakimovich, Y.; Pazmino, D. M.; Gandrillon, O.; Pelkmans, L.; Baroux, C.
10.1101/2023.09.28.559735 — molecular biology — Posted on 2023-09-28
410 Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion
Aleksandrova, E. V.; Wu, K. J. Y.; Tresco, B. I. C.; Syroegin, E. A.; Killeavy, E. E.; Balasanyants, S. M.; Svetlov, M. S.; Gregory, S. T.; Atkinson, G. C.; Myers, A. G.; Polikanov, Y. S.
10.1101/2023.09.27.559749 — molecular biology — Posted on 2023-09-28
413 Caspase-1 activates gasdermin A in all non-mammals
Billman, Z. P.; Kovacs, S. B.; Wei, B.; Kang, K.; Cisse, O. H.; Miao, E. A.
10.1101/2023.09.28.559989 — immunology — Posted on 2023-09-28
414 The interaction between NLRP1 and oxidized TRX1 involves a transient disulfide bond
Geeson, M. B.; Hsiao, J. C.; Tsamouri, L. P.; Ball, D. P.; Bachovchin, D. A.
10.1101/2023.09.27.559829 — immunology — Posted on 2023-09-28
418 Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractility-driven strain that inhibits fibril degradation
Saini, K.; Cho, S.; Tewari, M.; Jalil, A.; Wang, M.; Kasznel, A.; Yamamoto, K.; Chenoweth, D. M.; discher, d.
10.1101/2023.09.27.559759 — molecular biology — Posted on 2023-09-28
423 The impact of HTLV-1 expression on the 3D structure and expression of host chromatin
Bangham, C. R. M.; Yaguchi, H.; Melamed, A.; Ramanayake, S.; Kiik, H.; Witkover, A.
10.1101/2023.09.28.559884 — microbiology — Posted on 2023-09-28
424 Comparative reservoir competence of Peromyscus leucopus and mouse models for Borrelia burgdorferi B31
Bourgeois, J.; You, S. S.; Clendenen, L. H.; Shrestha, M.; Petnicki-Ocwieja, T.; Telford, S.; Hu, L.
10.1101/2023.09.28.559638 — microbiology — Posted on 2023-09-28
425 Inefficient transmission of African swine fever virus to sentinel pigs from environmental contamination under experimental conditions
Olesen, A. S.; Lohse, L.; Accensi, F.; Goldswain, H.; Belsham, G. J.; Botner, A.; Netherton, C.; Dixon, L. K.; Portugal, R.
10.1101/2023.09.28.559902 — microbiology — Posted on 2023-09-28
428 Analysis of nasopharyngeal microbiome patterns in Zambian infants with fatal acute febrile illness
Odom, A. R.; McClintock, J.; Gill, C. J.; Pieciak, R.; Ismail, A.; MacLeod, W. B.; Johnson, W. E.; Lapidot, R.
10.1101/2023.09.27.559805 — microbiology — Posted on 2023-09-28
430 Luteibacter sahnii sp. nov., a novel yellow-pigmented probiotic bacterium from rice seed microbiome.
Jaiswal, G.; Rana, R.; Nayak, P. K.; Chouhan, R.; Gandhi, S. G.; Patel, H. K.; Patil, P. B.
10.1101/2023.09.28.560004 — microbiology — Posted on 2023-09-28
433 Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike
Tan, T. J. C.; Odle, A.; Lei, R.; Matreyek, K. A.; Perlman, S.; Wong, L.-Y. R.; Wu, N. C.
10.1101/2023.09.27.559757 — microbiology — Posted on 2023-09-28
434 Exposure of Mycobacterium tuberculosis to human alveolar lining fluid shows temporal and strain-specific adaptation to the lung environment
Guardia, A. A.; Vilanova, A. G.; Schami, A. M.; Olmo-Fontanez, A. M.; Hicks, A.; Peters, J.; Maselli, D. J.; Wewers, M. D.; Wang, Y.; Torrelles, J. B.
10.1101/2023.09.27.559381 — microbiology — Posted on 2023-09-28
438 Deep Variational Autoencoders for Population Genetics
Geleta, M.; Mas Montserrat, D.; Giro-i-Nieto, X.; Ioannidis, A. G.
10.1101/2023.09.27.558320 — bioinformatics — Posted on 2023-09-28
441 Phased assembly of neo-sex chromosomes reveals extensive Y degeneration and rapid genome evolution in Rumex hastatulus
Sacchi, B. M.; Humphries, Z.; Kruzlicova, J.; Bodlakova, M.; Pyne, C.; Choudhury, B.; Gong, Y.; Bacovsky, V.; Hobza, R.; Barrett, S. C. H.; Wright, S. I.
10.1101/2023.09.26.559509 — evolutionary biology — Posted on 2023-09-28
444 Inhibiting Glutamine Metabolism Blocks Coronavirus Replication in Mammalian Cells
Greene, K. S.; Choi, A.; Chen, M.; Yang, N.; Li, R.; Qiu, Y.; Lukey, M. J.; Rojas, K. S.; Shen, J.; Wilson, K. F.; Katt, W. P.; Whittaker, G. R.; Cerione, R. A.
10.1101/2023.09.27.559756 — molecular biology — Posted on 2023-09-28
445 Inhibition of SARS-CoV-2 Infection in Human Airway Epithelium with a Xeno-Nucleic Acid Aptamer
Razi, N.; Li, W.; Ignacio, M. A.; Loube, J. M.; Agostino, E. L.; Zhu, X.; Scull, M. A.; DeStefano, J. J.
10.1101/2023.09.27.559799 — microbiology — Posted on 2023-09-28
447 Human enteric glia diversity in health and disease: new avenues for the treatment of Hirschsprung disease
Windster, J. D.; Kuil, L. E.; Kakiailatu, N. J. M.; Antanaviciute, A.; Sacchetti, A.; MacKenzie, K. C.; Peulen-Zink, J.; Kan, T. W.; Bindels, E.; de Pater, E.; Doukas, M.; Yousefi, S.; Barakat, T. S.; Meeussen, C. J. H. M.; Sloots, P. C. E. J.; Wijnen, R. M. H.; Parikh, K. B.; Boesmans, W.; Melotte, V.; Hofstra, R. M. W.; Simmons, A.; Alves, M.
10.1101/2023.09.26.559481 — pathology — Posted on 2023-09-28
448 Loss of embryonically-derived Kupffer cells during hypercholesterolemia accelerates atherosclerosis development
Fima, R.; Dussaud, S.; Benbida, C.; Blanchet, M.; Lanthiez, F.; Poupel, L.; Brambilla, C.; Moreau, M.; Boissonnas, A.; Gautier, E.; Huby, T.
10.1101/2023.09.26.559586 — pathology — Posted on 2023-09-28
449 The invasive lobular cancer cell line encyclopedia (ICLE) for studying potential biomarkers and exploring therapeutic opportunities
Shah, O. S.; Chen, F.; Webn, A.; Kashiparekh, A.; Savariau, L.; Clifford, B.; Hooda, J.; Atkinson, J. M.; Oesterreich, S.; Lee, A. V.
10.1101/2023.09.26.559548 — cancer biology — Posted on 2023-09-28
450 Lymphoma B cells remodel bone marrow stromal cell organization and function to induce a supportive cancer-associated fibroblast network
Dessauge, E.; Brauge, B.; Leonard, S.; Roulois, D.; Monvoisin, C.; Lejeune, T.; Destin, J.; Jouan, F.; Llamas-Gutierrez, F.; Mourcin, F.; TARTE, K.
10.1101/2023.09.26.559605 — cancer biology — Posted on 2023-09-28
451 GeneCompass: Deciphering Universal Gene Regulatory Mechanisms with Knowledge-Informed Cross-Species Foundation Model
Yang, X.; Liu, G.; Feng, G.; Bu, D.; Wang, P.; Jiang, J.; Chen, S.; Yang, Q.; Zhang, Y.; Man, Z.; Liang, Z.; Wang, Z.; Li, Y.; Li, Z.; Liu, Y.; Tian, Y.; Li, A.; Dong, J.; Hu, Z.; Fang, C.; Miao, H.; Cui, L.; Deng, Z.; Jiang, H.; Cui, W.; Zhang, J.; Yang, Z.; Li, H.; He, X.; Zhong, L.; Zhou, J.; Wang, Z.; Long, Q.; Xu, P.; Wang, H.; Meng, Z.; Wang, X.; Wang, Y.; Wang, Y.; Zhang, S.; Guo, J.; Zhao, Y.; Zhou, Y.; Li, F.; Liu, J.; Chen, Y.; Yang, G.; Li, X.
10.1101/2023.09.26.559542 — bioinformatics — Posted on 2023-09-28
453 Tuning electrical spiking of Schizophyllum commune with light
Browner, D.; Adamatzky, A.; Schunselaar, E.; Wösten, H.; Ayres, P.
10.1101/2023.09.26.559269 — bioengineering — Posted on 2023-09-28
454 Mapping the anatomical and transcriptional landscape of early human fetal ovary development
McGlacken-Byrne, S. M.; Del Valle, I.; Xenakis, T.; Simcock, I. C.; Suntharalingham, J. P.; Buonocore, F.; Crespo, B.; Moreno, N.; Liptrot, D.; Niola, P.; Brooks, T.; Conway, G. S.; Dattani, M. T.; Arthurs, O.; Solanky, N.; Achermann, J.
10.1101/2023.09.26.558771 — genomics — Posted on 2023-09-28
455 Evolution of gene expression across brain regions in behaviorally divergent deer mice
Kautt, A.; Chen, J.; Lewarch, C. L.; Hu, C.; Turner, K.; Lassance, J.-M.; Baier, F.; Bedford, N. L.; Bendesky, A.; Hoekstra, H. E.
10.1101/2023.09.28.559844 — evolutionary biology — Posted on 2023-09-28
457 Biallelic non-productive enhancer-promoter interaction precedes imprinted expression of Kcnk9 during mouse neural commitment
Rojas, C. R.; Cercy, J.; Perillous, s.; Gonthier-Gueret, C.; Montibus, B.; Maupetit-Mehouas, S.; Espinadel, A.; Dupre, M.; Hong, C. C.; Hata, K.; Nakabayashi, K.; Plagge, A.; Bouschet, T.; arnaud, p.; Vaillant, I.; Court, F.
10.1101/2023.09.26.559498 — molecular biology — Posted on 2023-09-28
460 Peds1 deficiency in zebrafish results in myeloid cell apoptosis and exacerbated inflammation
Arroyo, A. B.; Tyrkalska, S. D.; Bastida-Martinez, E.; Monera-Girona, A. J.; Canton-Sandoval, J.; Bernal-Carrion, M.; Garcia-Moreno, D.; Elias-Arnanz, M.; Mulero, V.
10.1101/2023.09.26.559500 — immunology — Posted on 2023-09-28
461 MARCO in alveolar macrophages negatively regulates Ace expression and aldosterone production
O'Brien, C. J. O.; Ratti, G.; Haberman, E. R.; Sweeney, C. A. P.; Gordon, S.; Domingos, A. I.
10.1101/2023.09.26.559578 — immunology — Posted on 2023-09-28
462 ATF2 phosphorylation is a key event in neuronal apoptosis, linking the DLK/LZK kinase cascade to JUN upregulation
Gomez Deza, J.; Nebiyou, M.; Alkaslasi, M. R.; El Touny, L. H.; Slavutsky, A. L.; Ashby, N.; Cheng, K.; Le Pichon, C. E.
10.1101/2023.09.27.559856 — neuroscience — Posted on 2023-09-28
465 Pan-viral ORFs discovery using Massively Parallel Ribosome Profiling
Weingarten-Gabbay, S.; Bauer, M. R.; Stanton, A. C.; Klaeger, S.; Verzani, E. K.; Lopez, D.; Clauser, K. R.; Carr, S. A.; Abelin, J. G.; Rice, C. M.; Sabeti, P. C.
10.1101/2023.09.26.559641 — systems biology — Posted on 2023-09-28
467 CYP79B2 and CYP79B3 contribute to root branching through production of the auxin precursor indole-3-acetonitrile
van Zelm, E.; Koevoets, I. T.; Meyer, A. J.; van der Velde, K.; De Zeeuw, T.; verstappen, f.; Holmer, R.; Kohlen, W.; Willemsen, V.; Gommers, C. M. M.; Testerink, C.
10.1101/2023.09.26.559630 — plant biology — Posted on 2023-09-28
468 Mitochondrial dsRNA from B-ALL cells stimulates mesenchymal stromal cells to become cancer associated fibroblasts
Burt, R. J.; Dey, A.; Akarca, A.; Allen, H.; Amerikanou, R.; Atkinson, S.; Auty, D.; Chatzigerou, J.; Cutler, E.; Guerra-Assuncao, J. A.; Kirschner, K.; Kumari, R.; Manji, J.; Marafioti, T.; Fielding, A. K.
10.1101/2023.09.26.559490 — cancer biology — Posted on 2023-09-28
469 Targeting EIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer
Zhao, N.; Kabotyanski, E.; Saltzman, A.; Malovannaya, A.; Yuan, X.; Reineke, L.; Lieu, N.; Gao, Y.; Pedroza, D.; Calderon, S.; Smith, A.; Hamor, C.; Safari, K.; Savage, S.; Zhang, B.; Zhou, J.; Soto, L.; Hilsenbeck, S.; Fan, C.; Perou, C.; Rosen, J.
10.1101/2023.09.28.559973 — cancer biology — Posted on 2023-09-28
470 Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models
Hendrickson, P. G.; Oristian, K. M.; Browne, M. R.; Lou, L.; Ma, Y.; Cardona, D. M.; Linardic, C. M.; Kirsch, D. G.
10.1101/2023.09.26.559519 — cancer biology — Posted on 2023-09-28
472 The structural landscape and diversity of Pyricularia oryzae MAX effectors revisited
Lahfa, M.; BARTHE, P.; DEGUILLEN, K.; Cesari, S.; RAJI, M.; Kroj, T.; Le Naour--Vernet, M.; Hoh, F.; Gladieux, P.; ROUMESTAND, C.; Gracy, J.; Declerck, N.; Padilla, A.
10.1101/2023.09.26.559520 — bioinformatics — Posted on 2023-09-28
475 TransGeneSelector: A Transformer-based Approach Tailored for Key Gene Mining with Small Plant Transcriptomic Datasets
Huang, K.; Tian, J.; Sun, L.; Xie, P.; Zhou, S.; Deng, A.; Mo, P.; Zhou, Z.; Jiang, M.; Li, G.; Wang, Y.; Jiang, X.
10.1101/2023.09.26.559592 — bioinformatics — Posted on 2023-09-28
477 Direct extrusion of multifascicle prevascularized human skeletal muscle for volumetric muscle loss surgery
Duong, V. T.; Dang, T. T.; Le, V. P.; Le, T. H.; Nguyen, C. T.; Phan, H. L.; Seo, J.; Back, S. H.; Koo, K.-i.
10.1101/2023.09.26.559212 — bioengineering — Posted on 2023-09-28
480 Integrated single-cell multiome analysis reveals muscle fiber-type gene regulatory circuitry modulated by endurance exercise
Rubenstein, A. B.; Smith, G. R.; Zhang, Z.; Chen, X.; Chambers, T. L.; Ruf-Zamojski, F.; Mendelev, N.; Cheng, W. S.; Zamojski, M.; Amper, M. A. S.; Nair, V. D.; Marderstein, A. R.; Montgomery, S. B.; Troyanskaya, O. G.; Zaslavsky, E.; Trappe, T.; Trappe, S.; Sealfon, S. C.
10.1101/2023.09.26.558914 — genomics — Posted on 2023-09-28
489 IL-2-induced Stat3 Signaling is Critical for Effector Treg Cell Programming
Dean, E. C.; DiToro, D. F.; Pham, D.; Gao, M.; Frey, B. F.; Harbour, S. N.; Figge, D. A.; Miller, A. T.; Glassman, C. R.; Garcia, K. C.; Hatton, R. D.; Weaver, C.
10.1101/2023.09.26.559434 — immunology — Posted on 2023-09-28
493 DeepGO-SE: Protein function prediction as Approximate Semantic Entailment
Kulmanov, M.; Guzman-Vega, F. J.; Duek Roggli, P.; Lane, L.; Arold, S. T.; Hoehndorf, R.
10.1101/2023.09.26.559473 — bioinformatics — Posted on 2023-09-28
497 Validation of cross progeny variance genomic prediction using simulations and experimental data in winter elite bread wheat
Oget-Ebrad, C.; Heumez, E.; Duchalais, L.; Goudemand-Dugue, E.; Oury, F.-X.; Elsen, J.-M.; Bouchet, S.
10.1101/2023.09.26.558758 — genomics — Posted on 2023-09-28
499 Species-specific epigenetic responses to drought stress of two sympatric oak species reflect their ecological preferences.
Rubio, B.; Le Provost, G.; Brachi, B.; Gerardin, T.; Brendel, O.; Tost, J.; Daviaud, C.; Gallusci, P.
10.1101/2023.09.26.559529 — genomics — Posted on 2023-09-28
503 Bringing circuit theory into spatial occupancy models to assess landscape connectivity
Kervellec, M.; Couturier, T.; Bauduin, S.; Chenesseau, D.; Defos du Rau, P.; Drouet-Hoguet, N.; Duchamp, C.; Steinmetz, J.; Vandel, J.-M.; Gimenez, O.
10.1101/2023.09.26.559320 — ecology — Posted on 2023-09-28
504 Endometrial zinc transporter Slc39a10/Zip10 is indispensable for progesterone responsiveness and successful pregnancy in mice
KAWATA, Y.; TERAKAWA, J.; TAKESHITA, A.; NAMIKI, T.; KAGEYAMA, A.; NOGUCHI, M.; MURAKAMI, H.; FUKADA, T.; ITO, J.; KASHIWAZAKI, N.
10.1101/2023.09.26.559476 — molecular biology — Posted on 2023-09-28
505 Multimodal identification of rare potent effector CD8 T cells in solid tumors
Ray, A.; Bassette, M.; Hu, K. H.; Pass, L. F.; Samad, B.; Combes, A.; Johri, V.; Davidson, B.; Hernandez, G.; Zaleta-Linares, I.; Krummel, M. F.
10.1101/2023.09.26.559470 — immunology — Posted on 2023-09-28
506 Full-Length Single-Molecule Protein Fingerprinting
Filius, M.; van Wee, R.; de Lannoy, C.; Westerlaken, I.; Li, Z.; Kim, S. H.; de Agrela Pinto, C.; Wu, Y.; Boons, G.-J.; Pabst, M.; de Ridder, D.; Joo, C.
10.1101/2023.09.26.559471 — biophysics — Posted on 2023-09-28
512 The polarity protein Yurt associates with the lateral domain via basic and hydrophobic motifs embedded in its FERM domain
Alende, C.; Gamblin, C. L.; Corriveau, F.; Jette, A.; Parent-Prevost, F.; Biehler, C.; Majeau, N.; Laurin, M.; Laprise, P.
10.1101/2023.09.28.559937 — cell biology — Posted on 2023-09-28
513 The nuclear basket regulates distribution and mobility of nuclear pore complexes in budding yeast
Zsok, J.; Simon, F.; Bayrak, G.; Isaki, L.; Kerff, N.; Wolstenholme, A.; Weiss, L. E.; Dultz, E.
10.1101/2023.09.28.558499 — cell biology — Posted on 2023-09-28
514 Genomic analyses correspond with deep persistence of peoples of Blackfoot Confederacy from glacial times
First Rider, D.; Crop Eared Wolf, A.; Murray, J.; de Flamingh, A.; Campelo dos Santos, A. L.; Lanoe, F.; Zedeno, M. N.; DeGiorgio, M.; Lindo, J.; Malhi, R. S.
10.1101/2023.09.25.559300 — genomics — Posted on 2023-09-28
515 Proteolytic activation of fatty acid synthase signals pan-stress resolution
Wei, H.; Weaver, Y. M.; Yang, C.; Zhang, Y.; Hu, G.; Karner, C. M.; DeBerardinis, R. J.; Weaver, B. P.
10.1101/2023.09.27.559743 — molecular biology — Posted on 2023-09-28
516 Human lower leg muscle pump acts like a stream diversion pump during locomotion
Tauraginskii, R. A.; Lurie, F.; Simakov, S.; Agalarov, R.; Khramtsov, P.; Babushkin, M.; Borsuk, D.; Galchenko, M.
10.1101/2023.09.25.559436 — physiology — Posted on 2023-09-28
517 EZH2 deletion does not impact acinar cell regeneration but restricts progression to pancreatic cancer in mice
Jaune-Pons, E.; Wang, X.; Mousavi, F.; El kaoutari, A.; Berger, K.; Johnson, C.; Martin, M.; Aggarwal, S.; Brar, S.; Muhammad, K.; Shooshtari, P.; Mathison, A.; Dusetti, N.; Urrutia, R.; Lomberk, G.; Pin, C. L.
10.1101/2023.09.25.559339 — cancer biology — Posted on 2023-09-28
520 CITE-seq reveals inhibition of NF-kB pathway in B cells from vitamin D-treated multiple sclerosis patients
Galoppin, M.; Rival, M.; Louis, A.; Kari, S.; Soldati, S.; Engelhardt, B.; Astier, A.; Marin, P.; Thouvenot, E.
10.1101/2023.09.25.559400 — genomics — Posted on 2023-09-28
522 Development of LIBRA-seq for the Guinea Pig Model System as a Tool for the Evaluation of Antibody Responses to Multivalent HIV-1 Vaccines
Vukovich, M. J.; Raju, N.; Kgagudi, P.; Manamela, N. P.; Abu-Shmais, A. A.; Gripenstraw, K. R.; Wasdin, P. T.; Shen, S.; Dwyer, B.; Akoad, J.; Lynch, R. M.; Montefiori, D. C.; Richardson, S. I.; Moore, P. L.; Georgiev, I. S.
10.1101/2023.09.25.559382 — immunology — Posted on 2023-09-28
523 Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2 responding CD4+ T cells
Sandoval, S.; Malany, K.; Thongphanh, K.; Martinez, C. A.; Goodson, M. L.; Souza, F. d. C.; Lin, L.-W.; Pennington, J.; Lein, P. J.; Kerkvliet, N. I.; Ehrlich, A. K.
10.1101/2023.09.25.559429 — immunology — Posted on 2023-09-28
524 Science abhors a surveillance vacuum: detection of ticks and tick-borne bacteria in southern New Mexico through passive surveillance
Harman, P. R.; Mendell, N. L.; Harman, M. M.; Draney, P. A.; Boyle, A. T.; Gompper, M. E.; Orr, T. J.; Bouyer, D. H.; Teel, P. D.; Hanley, K.
10.1101/2023.09.25.559416 — zoology — Posted on 2023-09-28
526 Hematopoietic Stem Cells Undergo Differentiation State Reprogramming to Overcome Venetoclax Sensitivity in Patients with Myelodysplastic Syndromes
Rodriguez Sevilla, J. J.; Ganan-Gomez, I.; Ma, F.; Chien, K.; Montalban-Bravo, G.; Kanagal-Shamanna, R.; Loghavi, S.; Adema, V.; Bazinet, A.; Garcia-Manero, G.; Colla, S.
10.1101/2023.09.25.559439 — cancer biology — Posted on 2023-09-28
527 The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics
Mc Cartney, A. M.; Formenti, G.; Mouton, A.; Ciofi, C.; Waterhouse, R. M.; Mazzoni, C. J.; De Panis, D.; Schlude Marins, L. S.; Leitao, H. G.; Diedericks, G.; Kirangwa, J.; Morselli, M.; Salces, J.; Escudero, N.; Iannucci, A.; Natali, C.; Svardal, H.; Fernandez, R.; De Pooter, T.; Joris, G.; Strazisar, M.; Wood, J.; Herron, K. E.; Seehausen, O.; Watts, P. C.; Shaw, F.; Davey, R. P.; Minotto, A.; Fernandez Gonzalez, J. M.; Bohne, A.; Alegria, C.; Alioto, T.; Alves, P. C.; Amorim, I. R.; Aury, J.-M.; Backstrom, N.; Baldrian, P.; Ballarin, L.; Baltrunaite, L.; Barta, E.; BedHom, B.; Belser, C.; B
10.1101/2023.09.25.559365 — genomics — Posted on 2023-09-28
532 Microevolution of clade II isolates of Candida auris highlights multifaceted intra-clade heterogeneity in acquiring resistance towards amphotericin B
Chauhan, A.; Kumar, P.; Kumar, M.; Narayanan, A.; Yadav, K.; Ali, B.; Saini, A.; Singh, A.; Banerjee, A.; Rudramurthy, S. M.; Chakrabarti, A.; Mondal, A. K.; Gaur, N. A.; Sanyal, K.; Prasad, R.
10.1101/2023.09.20.558730 — microbiology — Posted on 2023-09-28
533 Distinct transcriptional profiles of maternal and fetal placental macrophages at term are associated with gravidity
Ozarslan, N.; Robinson, J. F.; Buarpung, S.; Kim, M. Y.; Ansbro, M. R.; Akram, J.; Montoya, D. J.; Kamya, M. R.; Kakuru, A.; Dorsey, G.; Rosenthal, P. J.; Cheng, G.; Feeney, M. E.; Fisher, S. J.; Gaw, S. L.
10.1101/2023.09.25.559419 — immunology — Posted on 2023-09-28
534 Leaf δ13C reveals post-photosynthetic fractionation during ontogeny in a C4 grass
Yu, Y. Z.; Liu, H. T.; Yang, F.; Li, L.; Schaeufele, R.; Tcherkez, G.; Schnyder, H.; Gong, X. Y.
10.1101/2023.09.25.559424 — plant biology — Posted on 2023-09-28
535 The wheat powdery mildew resistance gene Pm4 also confers resistance to wheat blast
O'Hara, T.; Steed, A.; Goddard, R.; Gaurav, K.; Arora, S.; Quiroz-Chavez, J.; Ramirez-Gonzalez, R.; Badgami, R.; Gilbert, D.; Sanchez-Martin, J.; Wingen, L.; Feng, C.; Jiang, M.; Cheng, S.; Dreisigacker, S.; Keller, B.; Wulff, B.; Uauy, C.; Nicholson, P.
10.1101/2023.09.26.559489 — plant biology — Posted on 2023-09-28
537 Evolution of wheat blast resistance gene Rmg8 accompanied by differentiation of variants recognizing the powdery mildew fungus
Asuke, S.; Morita, K.; Shimizu, M.; Abe, F.; Terauchi, R.; Nago, C.; Takahashi, Y.; Shibata, M.; Yoshioka, M.; Iwakawa, M.; Kishi-Kaboshi, M.; Su, Z.; Nasuda, S.; Handa, H.; Fujita, M.; Tougou, M.; Hatta, K.; Mori, N.; Matsuoka, Y.; Kato, K.; Tosa, Y.
10.1101/2023.09.26.559445 — plant biology — Posted on 2023-09-28
540 Kinetochore and ionomic adaptation to whole genome duplication
Bray, S. M.; Hamala, T.; Zhou, M.; Busoms, S.; Fischer, S.; Desjardins, S. D.; Mandakova, T.; Moore, C.; Mathers, T. C.; Cowan, L.; Monnahan, P.; Koch, J.; Wolf, E. M.; Lysak, M. A.; Kolar, F.; Higgins, J. D.; Koch, M. A.; Yant, L.
10.1101/2023.09.27.559727 — evolutionary biology — Posted on 2023-09-28
541 Post-mortem AT-8 reactive tau species correlate with non-plaque Aβ levels in the frontal cortex of non-AD and AD brains
Malik, N.; Miah, M.; Galgani, A.; McAleese, K.; Walker, L.; LeBeau, F.; Attems, J.; Outeiro, T.; Thomas, A.; Koss, D.
10.1101/2023.09.27.559720 — neuroscience — Posted on 2023-09-28
543 Light management by algal aggregates in living photosynthetic hydrogels.
Chua, S. T.; Smith, A.; Murthy, S.; Murace, M.; Yang, H.; Kuhl, M.; Cicuta, P.; Smith, A. G.; Wangpraseurt, D.; Vignolini, S.
10.1101/2023.09.28.559714 — plant biology — Posted on 2023-09-28
544 Transcriptional acclimation to warming temperatures of the Australian alpine herb Wahlenbergia ceracea
Notarnicola, R. F.; Arnold, P. A.; Feng, Z.-P.; Hamilton, J.; Jones, A.; Loke, S.; Nicotra, A. B.; Schwessinger, B.; Ganguly, D. R.
10.1101/2023.09.27.559694 — plant biology — Posted on 2023-09-28
545 Transcriptional reactivation of the tRNASer/tRNATyr gene cluster in Arabidopsis thaliana root tip
Hummel, G.; Kumari, P.; Wang, L.; Mai, Y.-X.; Wang, N.; Shala, N.; Kaya, E. C.; Wang, J.-W.; Liu, C.
10.1101/2023.09.27.559738 — plant biology — Posted on 2023-09-28
547 The shape and volume of air, kernels, and cracks, in a nutshell
Amezquita, E. J.; Quigley, M. Y.; Brown, P. J.; Munch, E.; Chitwood, D. H.
10.1101/2023.09.26.559651 — plant biology — Posted on 2023-09-28
548 Lipid constituents from Cissus trifoliata stems
Lopez, L. F. M.; Llerena, J. L. G.; Rodriguez, B. A. E.; Renteria, I. B.; Corona, M. d. R. C.
10.1101/2023.09.27.559825 — plant biology — Posted on 2023-09-28
549 Obesity-elicited macrophages shape CD9hi progenitor fate to promote adipose tissue fibrosis and dysfunction
Askia, H.; Dussaud, S.; Chaves de Oliveira, M.; Oliveira, A.; Poupel, L.; Rebiere, C.; Ouhachi, M.; Manuel, R.; Merabtene, F.; Genser, L.; Aron-Wisnewsky, J.; Moreau, M.; Yvan-Charvet, L.; Ferreira, A.; Huby, T.; Clement, K.; Marcelin, G.; Gautier, E.
10.1101/2023.09.26.559540 — pathology — Posted on 2023-09-28
550 Lesions in a songbird vocal circuit increase variability in song syntax
Koparkar, A.; Warren, T. L.; Charlesworth, J. D.; Shin, S.; Brainard, M. S.; Veit, L.
10.1101/2023.07.25.550508 — neuroscience — Posted on 2023-09-28
551 BaRDIC: robust peak calling for RNA-DNA interaction data
Mylarshchikov, D. E.; Nikolskaya, A. I.; Bogomaz, O. D.; Zharikova, A. A.; Mironov, A. A.
10.1101/2023.09.21.558815 — bioinformatics — Posted on 2023-09-28
554 Reduced discrimination between signals of danger and safety but not overgeneralization is linked to exposure to childhood adversity in healthy adults
Klingelhoefer-Jens, M.; Hutterer, K.; Schiele, M. A.; Leehr, E.; Schuemann, D.; Rosenkranz, K.; Boehnlein, J.; Repple, J.; Deckert, J.; Domschke, K.; Dannlowski, U.; Lueken, U.; Reif, A.; Romanos, M.; Zwanzger, P.; Pauli, P.; Gamer, M.; Lonsdorf, T. B.
10.1101/2023.09.26.559474 — neuroscience — Posted on 2023-09-28
556 Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes
Reus, L. M.; Boltz, T.; Francia, M.; Bot, M.; Ramesh, N.; Koromina, M.; Pijnenburg, Y. A. L.; den Braber, A.; van der Flier, W. M.; Visser, P. J.; van der Lee, S. J.; Tijms, B.; Teunissen, C. E.; Olde Loohuis, L. M.; Ophoff, R. A.
10.1101/2023.09.26.559021 — genomics — Posted on 2023-09-27
557 Systematic perturbations of SETD2, NSD1, NSD2, NSD3 and ASH1L reveals their distinct contributions to H3K36 methylation
Shipman, G.; Padilla, R.; Horth, C.; Hu, B.; Bareke, E.; Vitorino, F.; Gongora, J.; Garcia, B.; Lu, C.; Majewski, J.
10.1101/2023.09.27.559313 — genomics — Posted on 2023-09-27
559 An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm
Grau-Bove, X.; Subirana, L.; Meister, L.; Soubigou, A.; Neto, A.; Elek, A.; Fornas, O.; Gomez-Skarmeta, J. L.; Tena, J. J.; Irimia, M.; Bertrand, S.; Sebe-Pedros, A.; Escriva, H.
10.1101/2023.09.26.559513 — evolutionary biology — Posted on 2023-09-27
560 Development of novel genetically-encoded fluorescent probes to track ceramides during phagocytosis
Girik, V.; Van Ek, L.; Dentand Quadri, I.; Azam, M.; Cruz Cobo, M.; Mandavit, M.; Riezman, I.; Riezman, H.; Gavin, A.-C.; Nunes-Hasler, P.
10.1101/2023.09.27.559623 — cell biology — Posted on 2023-09-27
561 Temporal Dynamics and Stoichiometry in Notch Signaling - from Notch Synaptic Complex Formation to NICD Nuclear Entry
Tveriakhina, L.; Scanavachi, G.; Egan, E. D.; Correia, R. B. D. C.; Martin, A. P.; Rogers, J. M.; Yodh, J. S.; Aster, J. C.; Kirchhausen, T.; Blacklow, S.
10.1101/2023.09.27.559780 — cell biology — Posted on 2023-09-27
562 The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation
Wachalska, M.; Riepe, C.; Slusarz, M. J.; Graul, M.; Borowski, L. S.; Qiao, W.; Foltynska, M.; Carette, J. E.; Bienkowska-Szewczyk, K.; Szczesny, R. J.; Kopito, R. R.; Lipinska, A. D.
10.1101/2023.09.27.559663 — cell biology — Posted on 2023-09-27
563 Septins Enable T Cell Contact Guidance via Amoeboid-Mesenchymal Switch
Zhovmer, A. S.; Manning, A.; Smith, C.; Wang, J.; Ma, X.; Tsygankov, D.; Dokholyan, N. V.; Cartagena-Rivera, A. X.; Singh, R.; Tabdanov, E. D.
10.1101/2023.09.26.559597 — cell biology — Posted on 2023-09-27
565 The IRE1α/XBP1/Myomaker axis drives myoblast fusion in adult skeletal muscle
Joshi, A. S.; Da Silva, M. T.; Roy, A.; Koike, T. E.; Wu, M.; Castillo, M. B.; Gunaratne, P. H.; Liu, Y.; Iwawaki, T.; Kumar, A.
10.1101/2023.09.26.559625 — cell biology — Posted on 2023-09-27
566 Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury
Varadharajan, V.; Ramachandiran, I.; Massey, W. J.; Jain, R.; Banerjee, R.; Horak, A. J.; McMullen, M. R.; Huang, E.; Bellar, A.; Lorkowski, S. W.; Gulshan, K.; Helsley, R. N.; James, I.; Pathak, V.; Dasarathy, J.; Welch, N.; Dasarathy, S.; Streem, D.; Reizes, O.; Allende, D. S.; Smith, J. D.; Simcox, J.; Nagy, L. E.; Brown, J. M.
10.1101/2023.09.26.559533 — cell biology — Posted on 2023-09-27
567 LRRK2 kinase dependent and independent function on endolysosomal repair promotes macrophage cell death
Morrison, R.; Mihaylov, S. R. G.; Luk, C. H.; Rodgers, A.; Athanasiadi, N.; Morris, H.; Pellegrino, E.; Ultanir, S. K.; Gutierrez, M. G.
10.1101/2023.09.27.559807 — cell biology — Posted on 2023-09-27
569 A Window into Mammalian Basement Membrane Development: Insights from the mTurq2-Col4a1 Mouse Model
Jones, R. A.; Trejo, B.; Sil, P.; Little, K. A.; Pasolli, H. A.; Joyce, B.; Posfai, E.; Devenport, D.
10.1101/2023.09.27.559396 — cell biology — Posted on 2023-09-27
570 Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids
Cao, X.; Wu, X.; Zhao, L.; Zheng, J.; Jin, X.; Hao, X.; Winderickx, J.; Liu, S.; Chen, L.; Liu, B.
10.1101/2023.09.27.559647 — cell biology — Posted on 2023-09-27
572 Correlation of calcium multiphoton with ultrastructural STED imaging of the slit diaphragm in the same glomerulus.
Wiesner, E.; Binz-Lotter, J.; Hackl, A.; Unnersjoe-Jess, D.; Rutkowski, N.; Benzing, T.; Hackl, M. J.
10.1101/2023.09.27.559730 — cell biology — Posted on 2023-09-27
573 Contact-FP: a dimerization-dependent fluorescent protein toolkit for visualizing membrane contact site dynamics
Miner, G. E.; Smith, S. Y.; Showalter, W. K.; So, C. M.; Ragusa, J. V.; Powers, A. E.; Zanellati, M. C.; Hsu, C.-H.; Marchan, M. F.; Cohen, S.
10.1101/2023.09.27.559820 — cell biology — Posted on 2023-09-27
574 Gut microbial community in proboscis monkeys: implications for effects of geographical and social factors
Jose, L.; Lee, W.; Hanya, G.; Tuuga, A.; Goossens, B.; Tangah, J.; Matsuda, I.; Subbiah, V. K.
10.1101/2023.03.14.532648 — microbiology — Posted on 2023-09-27
578 BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss.
Shields, M. A.; Metropulos, A. E.; Spaulding, C.; Hirose, T.; Ohno, S.; Pham, T. N.; Munshi, H. G.
10.1101/2023.09.14.557654 — pathology — Posted on 2023-09-27
580 A quantitative approach to measure and predict microbiome response to antibiotics
Tu, V.; Ren, Y.; Tanes, C.; Mukhopadhyay, S.; Daniel, S. G.; Li, H.; Bittinger, K.
10.1101/2023.01.27.525904 — bioinformatics — Posted on 2023-09-27
581 Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings
Sasse, A.; Ng, B.; Spiro, A.; Tasaki, S.; Bennett, D.; Gaiteri, C.; De Jager, P. L.; Chikina, M.; Mostafavi, S.
10.1101/2023.03.16.532969 — bioinformatics — Posted on 2023-09-27
583 Bioinformatic investigation of discordant sequence data for SARS-CoV-2: insights for robust genomic analysis during pandemic surveillance
Zufan, S. E.; Lau, K. A.; Donald, A.; Hoang, T.; Foster, C. S. P.; Sikazwe, C.; Theis, T.; Rawlinson, W. D.; Ballard, S. A.; Stinear, T. P.; Howden, B. P.; Jennison, A. V.; Seemann, T.
10.1101/2023.02.01.526694 — genomics — Posted on 2023-09-27
584 Actin-dependent recruitment of AGO2 to the zonula adherens
Bridges, M. C.; Nair-Menon, J.; Risner, A.; Jimenez, D. W.; Daulagala, A. C.; Kingsley, C.; Davis, M. E.; Kourtidis, A.
10.1101/2022.03.10.483874 — cell biology — Posted on 2023-09-27
585 Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies
Husser, M. C.; Pham, N. P.; Law, C.; Araujo, F. R. B.; Martin, V. J. J.; Piekny, A.
10.1101/2023.06.28.546942 — cell biology — Posted on 2023-09-27
586 The domed architecture of Giardias ventral disc is necessary for attachment and host pathogenesis
Hagen, K. D.; Nosala, C.; Hilton, N.; Mueller, A.; Holthaus, D.; Laue, M.; Klotz, C.; Aebischer, A.; Dawson, S. C.
10.1101/2023.07.02.547441 — microbiology — Posted on 2023-09-27
587 A fluidization transition of the cell envelope sets up a universal volume expansion pacemaker
Mukherjee, A.; Huang, Y.; Oh, S.; Sanchez, C.; Chang, Y.-F.; Liu, X.; Bradshaw, G. A.; Benites, N. C.; Paulsson, J.; Kirschner, M. W.; Sung, Y.; Elgeti, J.; Basan, M.
10.1101/2023.08.31.555748 — microbiology — Posted on 2023-09-27
588 Dynamic ventral disc contraction is necessary for Giardia attachment and host pathology
Nosala, C.; Hagen, K. D.; Guest, S. L.; Hilton, N. A.; Mueller, A.; Laue, M.; Klotz, C.; Aebischer, A.; Dawson, S. C.
10.1101/2023.07.04.547600 — microbiology — Posted on 2023-09-27
589 Minimal determinants for durable B cell antibody response towards virus-like antigens
Wholey, W.-Y.; Meyer, A. R.; Yoda, S.-T.; Chackerian, B.; Zikherman, J.; Cheng, W.
10.1101/2023.02.20.529089 — immunology — Posted on 2023-09-27
592 Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate
Rouleau, F. D.; Dube, A. K.; Gagnon-Arsenault, I.; Dibyachintan, S.; Pageau, A.; Despres, P. C.; Lagüe, P.; Landry, C. R.
10.1101/2023.09.27.559786 — biochemistry — Posted on 2023-09-27
593 Lessons from a multilaboratorial task force for diagnosis of a fatal toxoplasmosis outbreak in captive primates in Brazil
Schiffler, F. B.; Moreira, S. B.; Pereira, A. H. B.; Arruda, I. F.; Moreira, F. R. R.; D'arc, M.; Claro, I. M.; Pissinatti, T. d. A.; Cavalcante, L. T. d. F.; Miranda, T. d. S.; Cosentino, M. A. C.; de Oliveira, R. C.; de Jesus, J. F.; Assis, M. R. d. S.; de Oliveira, J. G.; da Silva, T. A. C.; Galliez, R. M.; Faffe, D. S.; de Jesus, J. G.; da Silva, M. S. B.; Bezerra, M. F.; Ferreira Junior, O. d. C.; Tanuri, A.; Castineiras, T. M. P. P.; Aguiar, R. S.; Faria, N. R.; Almeida, A. P.; Pissinatti, A.; Sabino, E. C.; Amendoeira, M. R. R.; de Lemos, E. R. S.; Ubiali, D. G.; Santos, A. F.
10.1101/2023.09.27.559677 — microbiology — Posted on 2023-09-27
596 Mapping the biochemical landscape of rubisco
Prywes, N.; Phillips, N. R.; Oltrogge, L. M.; de Pins, B.; Cowan, A. E.; Taylor-Kearney, L. J.; Chang, H. A.; Hall, L. N.; Bhatt, A.; Shih, P.; Milo, R.; Savage, D. F.
10.1101/2023.09.27.559826 — biochemistry — Posted on 2023-09-27
598 53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
Leriche, M.; Bonnet, C.; Jana, J.; Chhetri, G.; Mennour, S.; Martineau, S.; Pennaneach, V.; BUSSO, D.; Veaute, X.; Bertrand, P.; lambert, s. A.; Somyajit, K.; Uguen, P.; Vagner, S.
10.1101/2023.09.27.559698 — molecular biology — Posted on 2023-09-27
605 Temporal profiling of Salmonella transcriptional dynamics during macrophage infection using a comprehensive reporter library
Nguyen, T. H.; Diaz, O. R.; Rajendram, M.; Butler, D. S. C.; Wang, B. X.; Hinton, J. C. D.; Monack, D. M.; Huang, K. C.
10.1101/2023.09.27.559620 — microbiology — Posted on 2023-09-27
607 Identification of Host Restriction Factors Critical for Recombinant AAV Transduction of Polarized Human Airway Epithelium
Hao, S.; Zhang, X.; Ning, K.; Feng, Z.; Park, S. Y.; Kuz, C. A.; McFarlin, S.; Richart, D.; Cheng, F.; Zhang, E. Y.; Zhang-Chen, A.; Yan, Z.; Qiu, J.
10.1101/2023.09.27.559795 — microbiology — Posted on 2023-09-27
609 Host metabolic pathways essential for malaria and related hemoparasites in the infection of nucleated cells
Maurizio, M.; Masad, M.; Woods, K.; Caldelari, R.; Doench, J. G.; Naguleswaran, A.; Joly, D.; Fernandez, M. G.; Zemp, J.; Borteele, M.; Hatzimanikatis, V.; Heussler, V.; Rottenberg, S.; Olias, P.
10.1101/2023.09.27.559824 — microbiology — Posted on 2023-09-27
610 Engineered Lactiplantibacillus plantarum as a Biosensor Probe for the Lungs
Brasino, M.; Wagnell, E.; Manalo, E. C.; Drennan, S.; Fischer, J. M.; Merritt, J.
10.1101/2023.09.27.559779 — synthetic biology — Posted on 2023-09-27
612 RlmQ: A Newly Discovered rRNA Modification Enzyme Bridging RNA Modification and Virulence Traits in Staphylococcus aureus
Bahena-Ceron, R.; Teixeira, C.; Jaramillo Ponce, J. R.; Wolff, P.; Couzon, F.; Francois, P.; Klaholz, B.; Vandenesch, F.; Romby, P.; Moreau, K.; Marzi, S.
10.1101/2023.09.27.559750 — molecular biology — Posted on 2023-09-27
613 Genomic and Phenotypic Comparison of Polyhydroxyalkanoates Producing Strains of genus Caldimonas/Schlegelella
Musilova, J.; Kourilova, X.; Hermankova, K.; Bezdicek, M.; Ieremenko, A.; Dvorak, P.; Obruca, S.; Sedlar, K.
10.1101/2023.09.27.559687 — microbiology — Posted on 2023-09-27
618 Dairy practices select for thermostable endolysins in phages
Oechslin, F.; Zhu, X.; Morency, C.; Somerville, V.; Shi, R.; Moineau, S.
10.1101/2023.09.27.559745 — microbiology — Posted on 2023-09-27
619 Quantifying nutrient colimitation of microbial growth
Held, N. A.; Krishna, A.; Crippa, D.; Dragan, A.; Manhart, M.
10.1101/2023.09.27.559472 — microbiology — Posted on 2023-09-27
620 Influence of preprocessing, distortion correction and cardiac triggering on the quality of diffusion MR images of spinal cord
Schilling, K.; Combes, A.; Ramadass, K.; Rheault, F.; Sweeney, G.; Prock, L.; Sriram, S.; Cohen-Adad, J.; Gore, J. C.; Landman, B. A.; Smith, S.; O'Grady, K. P.
10.1101/2023.09.26.559530 — neuroscience — Posted on 2023-09-27
622 FAM210B is dispensable for erythroid differentiation in adult mice
Perfetto, M.; Rondelli, C. M.; Gillis, S.; Stratman, A. N.; Yien, Y. Y.
10.1101/2023.09.26.559581 — developmental biology — Posted on 2023-09-27
624 Neural circuit mechanisms underlying context-specific halting in Drosophila.
Sapkal, N.; Mancini, N.; Kumar, D. S.; Spiller, N.; Murakami, K.; Vitelli, G.; Bargeron, B.; Maier, K.; Eichler, K.; Jefferis, G. S. X. E.; Shiu, P.; Sterne, G. R.; Bidaye, S. S.
10.1101/2023.09.25.559438 — neuroscience — Posted on 2023-09-27
625 Dopamine neuron dysfunction and loss in the PrknR275W mouse model of Juvenile Parkinsonism
Regoni, M.; Zanetti, L.; Sevegnani, M.; Domenicale, C.; Magnabosco, S.; Patel, J. C.; Fernandes, M. K.; Monzani, E.; Comai, S.; Cherchi, L.; Ciammola, A.; Valtorta, F.; Morari, M.; Piccoli, G.; Rice, M. E.; Sassone, J.
10.1101/2023.09.26.559326 — neuroscience — Posted on 2023-09-27
630 Gut microbiota promotes enteroendocrine cell maturation and mitochondrial function
Alsudayri, A.; Perelman, S.; Chura, A.; Brewer, M.; McDevitt, M.; Drerup, C.; Ye, L.
10.1101/2023.09.27.558332 — developmental biology — Posted on 2023-09-27
631 Genomic evolution of SARS-CoV-2 variants of concern under in vitro neutralising selection pressure following two doses of the Pfizer-BioNTech BNT162b2 COVID-19 vaccine
Basile, K.; Agius, J. E.; Fong, W.; McPhie, K.; Fennel, M.; Ko, D.; Hueston, L.; Lam, C.; Arnott, A.; Chen, S. C.-A.; Maddocks, S.; O Sullivan, M. V. N.; Dwyer, D.; Sintchenko, V.; Kok, J.; Rockett, R. J.; CIDMLS COVID-19 Study Group,
10.1101/2023.09.24.558921 — microbiology — Posted on 2023-09-27
633 Proteome profiling of brain vessels in a mouse model of cerebrovascular pathology
Haqqani, A. S.; Mianoor, Z.; Star, A. T.; Detcheverry, F.; Stanimirovic, D. B.; Hamel, E.; Badhwar, A.
10.1101/2023.09.27.559361 — neuroscience — Posted on 2023-09-27
637 Convergent generation of atypical prions in knock-in mouse models of genetic prion disease
Mehra, S.; Bourkas, M. E. C.; Kaczmarczyk, L.; Stuart, E.; Arshad, H.; Griffin, J. K.; Frost, K. L.; Walsh, D. J.; Supattapone, S.; Booth, S. A.; Jackson, W. S.; Watts, J. C.
10.1101/2023.09.26.559572 — neuroscience — Posted on 2023-09-27
641 Sleep and circadian rhythm disruption by NPTX2 loss of function
Roh, S.-E.; Xiao, M.; Delgado, A.; Kwak, C.; Savonenko, A.; Bakker, A.; Kwon, H.-B.; Worley, P.
10.1101/2023.09.26.559408 — neuroscience — Posted on 2023-09-27
643 Primate Saccade Rhythmicity
Näher, T.; Zhang, Y.; Pandinelli, M.; Fries, P.
10.1101/2023.09.27.559710 — neuroscience — Posted on 2023-09-27
644 Listening to classical music influences brain connectivity in post-stroke aphasia: a pilot study
Chea, M.; Ben Salah, A.; Toba, M. N.; Zeineldin, R.; Kaufmann, B. C.; Weill-Chounlamountry, A.; Naccache, L.; Bayen, E.; Bartolomeo, P.
10.1101/2023.09.27.559699 — neuroscience — Posted on 2023-09-27
646 Spatial transcriptomics and single-nucleus RNA sequencing reveal a transcriptomic atlas of adult human spinal cord
Zhang, D.; Chen, Y.; Wei, Y.; Chen, H.; Wu, Y.; Wu, L.; Li, J.; Ren, Q.; Miao, C.; Zhu, T.; Liu, J.; Ke, B.; Zhou, C.
10.1101/2023.09.26.559582 — neuroscience — Posted on 2023-09-27
647 Sensorimotor Integration Supporting Perception Requires Syngap1 Expression in Cortex
Vaissiere, T.; Michaelson, S.; Creson, T.; Goins, J.; Fürth, D.; Balazsfi, D.; Rojas, C.; Golovin, R.; Meletis, K.; Miller, C.; O'Connor, D. H.; Rumbaugh, G.
10.1101/2023.09.27.559787 — neuroscience — Posted on 2023-09-27
649 Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera
Mühlemann, B.; Wilks, S. H.; Baracco, L.; Bekliz, M.; Carreno, J. M.; Corman, V. M.; Davis-Gardner, M. E.; Dejnirattisai, W.; Diamond, M.; Doueck, D.; Drosten, C.; Eckerle, I.; Edara, V. V.; Ellis, M.; Fouchier, R. A.; Frieman, M.; Godbole, S.; Haagmans, B.; Halfmann, P.; Henry, A. R.; Jones, T. C.; Katzelnick, L.; Kawaoka, Y.; Kimpel, J.; Krammer, F.; Lai, L.; Liu, C.; Lusvarghi, S.; Meyer, B.; Mongkolsapaya, J.; Montefiori, D.; Mykytyn, A. Z.; Netzl, A.; Pollett, S.; Rössler, A.; Screaton, G.; Shen, X.; Sigal, A.; Simon, V.; Subramanian, R.; Supasa, P.; Suthar, M.; Tureli, S.; Wang, W.; We
10.1101/2023.09.27.559689 — bioinformatics — Posted on 2023-09-27
652 Capturing temporal heterogeneity of communities: a temporal β-diversity based on Hill numbers and time series analysis
Sanchez-Ochoa, D. J.; Gonzalez, E. J.; Arizmendi, M. d. C.; Koleff, P.; Martell-Dubois, R.; Meave, J. A.; Perez-Mendoza, H. A.
10.1101/2023.09.25.559413 — ecology — Posted on 2023-09-27
653 DISTINCT METABOLIC STATES DIRECT RETINAL PIGMENT EPITHELIUM CELL FATE DECISIONS
Perez-Estrada, J. R.; Tangeman, J. A.; Proto-Newton, M.; Sanaka, H.; Smucker, B.; Del Rio-Tsonis, K.
10.1101/2023.09.26.559631 — developmental biology — Posted on 2023-09-27
654 Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts
Luo, Y.; Cao, K.; Chiu, J.; Chen, H.; Wang, H.-J.; Thornton, M. E.; Grubbs, B. H.; Kolb, M.; Parmacek, M. S.; Mishina, Y.; Shi, W.
10.1101/2023.09.26.559527 — developmental biology — Posted on 2023-09-27
656 p38-MAPK is prerequisite for the synthesis of SARS-CoV-2 protein
Mittal, P.; Khandelwal, N.; Chander, Y.; Verma, A.; Kumar, R.; Putatunda, C.; Barua, S.; Gulati, B. R.; Kumar, N.
10.1101/2023.09.27.559660 — microbiology — Posted on 2023-09-27
657 Quantifying brain connectivity signatures by means of polyconnectomic scoring
Libedinsky, I.; Helwegen, K.; Guerrero Simon, L.; Gruber, M.; Repple, J.; Kircher, T.; Dannlowski, U.; van den Heuvel, M.
10.1101/2023.09.26.559327 — neuroscience — Posted on 2023-09-27
659 A 4D transcriptomic map for the evolution of multiple sclerosis-like lesions in the marmoset brain
Lin, J.-P.; Brake, A.; Donadieu, M.; Lee, A.; Kawaguchi, R.; Sati, P.; Geschwind, D. H.; Jacobson, S.; Schafer, D. P.; Reich, D. S.
10.1101/2023.09.25.559371 — neuroscience — Posted on 2023-09-27
663 Sex divergent behavioral responses in platform-mediated avoidance and glucocorticoid receptor blockade
Halcomb, C. J.; Philipp, T. R.; Dhillon, P. S.; Cox, J. H.; Aguilar-Alvarez, R.; Vanderhoof, S. O.; Jasnow, A. M.
10.1101/2023.09.26.559122 — neuroscience — Posted on 2023-09-27
669 MMORF - FSL's MultiMOdal Registration Framework
Lange, F. J.; Arthofer, C.; Bartsch, A.; Douaud, G.; McCarthy, P.; Smith, S. M.; Andersson, J. L. R.
10.1101/2023.09.26.559484 — neuroscience — Posted on 2023-09-27
670 A Scalable Staining Strategy for Whole-Brain Connectomics
Lu, X.; Wu, Y.; Schalek, R. L.; Meirovitch, Y.; Berger, D. R.; Lichtman, J. W.
10.1101/2023.09.26.558265 — neuroscience — Posted on 2023-09-27
671 Randomness impacts specific priors building, visual exploration, and perception in object recognition
Gal, C.; Tincas, I.; Moca, V. V.; Ciuparu, A.; Dan, E. L.; Smith, M. L.; Gliga, T.; Muresan, R. C.
10.1101/2023.09.26.559544 — neuroscience — Posted on 2023-09-27
672 The Temporal Dynamics of Metacognitive Experiences Track Rational Adaptations in Task Performance
Vermeylen, L.; Braem, S.; Ivanchei, I. I.; Desender, K.; Gonzalez-Garcia, C.; Garcia-Roman, J. M.; Ruz, M.; Notebaert, W.
10.1101/2023.09.26.559523 — neuroscience — Posted on 2023-09-27
673 Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice
Matrongolo, M. J.; Ang, P. S.; Wu, J.; Jain, A.; Thackray, J. K.; Reddy, A.; Sung, C. C.; Barbet, G.; Hong, Y.-K.; Tischfield, M.
10.1101/2023.09.27.559761 — neuroscience — Posted on 2023-09-27
674 Expansion of interferon signaling-associated gene (ISAG)-hi T cells in early-onset Alzheimer's disease
Sirkis, D. W.; Solsberg, C. W.; Johnson, T. P.; Geier, E. G.; Bonham, L. W.; Miller, B. L.; Rabinovici, G. D.; Yokoyama, J. S.
10.1101/2023.09.26.559634 — neuroscience — Posted on 2023-09-27
676 Altered hierarchical gradients of intrinsic neural timescales in mild cognitive impairment and Alzheimer's disease
ZHANG, A.; Wengler, K.; Zhu, X.; Horga, G.; Goldberg, T.; lee, s.; For Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.09.26.559549 — neuroscience — Posted on 2023-09-27
679 A tale of two receptors: simultaneous targeting of NMDARs and 5-HT4Rs exerts additive effects against stress
Chen, B. K.; Luna, V. M.; Jin, M.; Shah, A.; Shannon, M. E.; Pauers, M. M.; Williams, B. L.; Pham, V.; Hunsberger, H. C.; Gardier, A. M.; Mendez-David, I.; David, D. J.; Denny, C. A.
10.1101/2023.09.27.559065 — neuroscience — Posted on 2023-09-27
682 Neocortico-hippocampal ripple-based coordination during naturalistic encoding
Silva, M.; Wu, X.; Sabio, M.; Conde-Blanco, E.; Roldan, P.; Donaire, A.; Carreno, M.; Axmacher, N.; Baldassano, C.; Fuentemilla, L.
10.1101/2023.09.27.559739 — neuroscience — Posted on 2023-09-27
686 Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon
Thieme, M.; Minadakis, N.; Himber, C.; Keller, B.; Xu, W.; rutowicz, K.; Matteoli, C.; Boehrer, M.; Rymen, B.; Laudencia-Chingcuanco, D.; Vogel, J. P.; Sibout, R.; Stritt, C.; Blevins, T.; Roulin, A. C.
10.1101/2023.09.25.559196 — genomics — Posted on 2023-09-27
687 Working together to control mutation: how collective peroxide detoxification determines microbial mutation rate plasticity
Green, R.; Wang, H.; Botchey, C.; Zhang, N.; Wadsworth, C.; McBain, A.; Paszek, P.; Krasovec, R.; Knight, C. G.
10.1101/2023.09.27.557722 — evolutionary biology — Posted on 2023-09-27
688 Survey of white-footed mice in Connecticut, USA reveals low SARS-CoV-2 seroprevalence and infection with divergent betacoronaviruses
Earnest, R.; Hahn, A. M.; Feriancek, N. M.; Brandt, M.; Filler, R. B.; Zhao, Z.; Breban, M. I.; Vogels, C. B. F.; Chen, N. F. G.; Koch, R. T.; Porzucek, A. J.; Sodeinde, A.; Garbiel, A.; Keanna, C.; Litwak, H.; Stuber, H. R.; Cantoni, J. L.; Pitzer, V. E.; Olarte Castillo, X. A.; Goodman, L. B.; Wilen, C. B.; Linske, M. A.; Williams, S. C.; Grubaugh, N. D.
10.1101/2023.09.22.559030 — ecology — Posted on 2023-09-27
689 Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo
Kober, D. L.; Caballero Van Dyke, M. C.; Eitson, J. L. E. L.; Rosenbaum, D.; Schoggins, J. W.
10.1101/2023.09.26.559550 — microbiology — Posted on 2023-09-27
690 SARS-CoV-2 Omicron BA.2.86: less neutralization evasion compared to XBB sub-variants
An, Y.; Zhou, X.; Tao, L.; Xie, H.; Li, D.; Wang, R.; Hu, H.; Xu, Z.; Dai, L.; Xu, K.; Gao, G. F.
10.1101/2023.09.26.559580 — immunology — Posted on 2023-09-27
694 Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending
Hu, Y.; Schwab, S.; Deiss, S.; Escudeiro, P.; Joiner, J. D.; Hartmann, M. D.; Lupas, A. N.; Alvarez, B. H.; Alva, V.; Dame, R. T.
10.1101/2023.02.26.530074 — molecular biology — Posted on 2023-09-27
695 Proteasome-dependent degradation of histone H1 subtypes is mediated by its C-terminal domain.
Garcia-Gomis, D. R.; Lopez-Gomez, J.; Calderon, A.; Andres, M. R.; Ponte, I.; Roque, A.
10.1101/2023.06.17.545431 — molecular biology — Posted on 2023-09-27
699 Parkinsons VPS35 mutation induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B
Pal, P.; Taylor, M.; Lam, P. Y.; Tonelli, F.; Hecht, C. A.; Lis, P.; Nirujogi, R. S.; Phung, T. K.; Yeshaw, W. M.; Jaimon, E.; Fasimoye, R.; Dickie, E. A.; Wightman, M.; Macartney, T.; Pfeffer, S. R.; Alessi, D. R.
10.1101/2023.06.07.544051 — neuroscience — Posted on 2023-09-27
707 Oscillatory brain activity as unified control mechanism for working memory and social cognition
Friedrich, E. V. C.; Hilla, Y.; Sterner, E. F.; Ostermeier, S. S.; Behnke, L.; Sauseng, P.
10.1101/2023.02.13.528423 — neuroscience — Posted on 2023-09-27
708 Targeting mosquito X-chromosomes reveals complex transmission dynamics of sex ratio distorting gene drives
Haber, D. A.; Arien, Y.; Lamdan, L. B.; Alcalay, Y.; Zecharia, C.; Krsticevic, F.; Yonah, E. S.; Avraham, R. D.; Windbichler, N.; Papathanos, P. A.
10.1101/2023.08.20.554004 — synthetic biology — Posted on 2023-09-27
711 Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike
Wang, Q.; Guo, Y.; Liu, L.; Schwanz, L. T.; Li, Z.; Ho, J.; Zhang, R. M.; Iketani, S.; Yu, J.; Huang, Y.; Qu, Y.; Valdez, R.; Lauring, A. S.; Gordon, A.; Wang, H. H.; Liu, L.; Ho, D. D.
10.1101/2023.09.24.559214 — microbiology — Posted on 2023-09-27
713 RNA-based sensitive fungal pathogen detection
Micheel, J.; Aron, F.; Kelani, A. A.; Girbardt, C.; Blango, M. G.; Walther, G.; Wollny, D.
10.1101/2023.09.26.559494 — microbiology — Posted on 2023-09-27
714 Organizing the coactivity structure of the hippocampus from robust to flexible memory
Gava, G. P.; Lefevre, L.; Broadbelt, T.; McHugh, S. B.; Lopes-dos-Santos, V.; Brizee, D.; Hartwich, K.; Sjoberg, H.; Perestenko, P. V.; Toth, R.; Sharott, A.; Dupret, D.
10.1101/2023.09.26.558975 — neuroscience — Posted on 2023-09-27
715 A new cell culture resource for investigations of reptilian gene function
Samudra, S. P.; Park, S.; Esser, E. A.; McDonald, T. P.; Borges, A. M.; Eggenschwiler, J.; Menke, D. B.
10.1101/2023.09.25.559349 — developmental biology — Posted on 2023-09-27
716 HaloTag display enables quantitative single-particle characterization and functionalization of engineered extracellular vesicles
Mitrut, R. E.; Stranford, D. M.; Chan, J. M.; Bailey, M. D.; Luo, M.; Meade, T. J.; Wang, M.; Leonard, J. N.
10.1101/2023.09.25.559433 — bioengineering — Posted on 2023-09-27
717 Evidence for kilometer-scale biophysical features at the Gulf Stream front
Gray, P. C.; Savelyev, I.; Cassar, N.; Levy, M.; Boss, E.; Lehahn, Y.; Bourdin, G.; Thompson, K. A.; Windle, A.; Gronniger, J.; Floge, S.; Hunt, D.; Silsbe, G.; Johnson, Z. I.; Johnston, D. W.
10.1101/2023.09.25.559383 — ecology — Posted on 2023-09-27
719 On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seeding experiments
Frey, L.; Ghosh, D.; Qureshi, B. M.; Rhyner, D.; Guerrero-Ferreira, R.; Pokharna, A.; Kwiatkowski, W.; Serdiuk, T.; Picotti, P.; Riek, R.; Greenwald, J.
10.1101/2023.06.25.546428 — biophysics — Posted on 2023-09-27
720 Elevated genetic risk for multiple sclerosis originated in Steppe Pastoralist populations
Barrie, W.; Yang, Y.; Irving-Pease, E.; Attfield, K. E.; Scorrano, G.; Jensen, L. T.; Armen, A. P.; Dimopoulos, E. A.; Stern, A.; Refoyo-Martinez, A.; Pearson, A.; Ramsoe, A.; Gaunitz, C.; Demeter, F.; Jorkov, M. L. S.; Moller, S. B.; Springborg, B.; Klassen, L.; Hyldgard, I. M.; Wickmann, N.; Vinner, L.; Korneliussen, T. S.; Allentoft, M. E.; Sikora, M.; Kristiansen, K.; Rodriguez, S.; Nielsen, R.; Iversen, A. K. N.; Lawson, D. J.; Fugger, L.; Willerslev, E.
10.1101/2022.09.23.509097 — evolutionary biology — Posted on 2023-09-27
722 Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature
Zane, F.; Bouzid, H.; Sosa Marmol, S.; Brazane, M.; Besse, S.; Molina, J. L.; Cansell, C.; Aprahamian, F.; Durand, S.; Ayache, J.; Antoniewski, C.; CARRE, C.; Todd, N.; Rera, M.
10.1101/2022.11.22.517330 — systems biology — Posted on 2023-09-27
724 DNA Tetrahedral Nanocages as a Promising Nanocarrier for Dopamine Delivery in Neurological Disorders
Singh, R.; Kansara, K.; Mandal, S.; Varshney, R.; Gupta, S.; Kumar, A.; Maiti, P. K.; Bhatia, D. D.
10.1101/2023.09.19.558434 — bioengineering — Posted on 2023-09-27
725 High performance enrichment-based genome sequencing to support the investigation of hepatitis A virus outbreaks
Zufan, S. E.; Mercoulia, K.; Kwong, J.; Judd, L. M.; Howden, B. P.; Seemann, T.; Stinear, T. P.
10.1101/2023.07.21.548488 — genomics — Posted on 2023-09-27
727 Deep learning to extract the meteorological by-catch of wildlife cameras
Alison, J.; Payne, S.; Alexander, J. M.; Bjorkman, A. D.; Clarke, V. R.; Gwate, O.; Huntsaar, M.; Iseli, E.; Lenoir, J.; Mann, H. M. R.; Steenhuisen, S.-L.; Hoye, T. T.
10.1101/2023.09.25.558780 — ecology — Posted on 2023-09-27
729 Molecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision
Shembrey, C.; Yang, R.; Casan, J.; Hu, W.; Sadras, T.; Prasad, K.; Shortt, J.; Johnstone, R. W.; Trapani, J. A.; Ekert, P. G.; Fareh, M.
10.1101/2023.09.26.557083 — molecular biology — Posted on 2023-09-26
730 N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs
Lee, E. S.; Smith, H. W.; Ihn, S. S.; Scalize de Olivera, L.; Wang, Y. E.; Jomphe, R. Y.; Nabeel-Shah, S.; Pu, S.; Greenblatt, J. F.; Palazzo, A. F.
10.1101/2023.06.20.545713 — molecular biology — Posted on 2023-09-27
733 Synchronized long-read genome, methylome, epigenome, and transcriptome for resolving a Mendelian condition
Vollger, M. R.; Korlach, J.; Eldred, K. C.; Swanson, E.; Underwood, J. G.; Munson, K. M.; Cheng, Y.-H. H.; Ranchalis, J.; Mao, Y.; Blue, E. E.; Schwarze, U.; Saunders, C. T.; Wenger, A. M.; Allworth, A.; Chanprasert, S.; Duerden, B. L.; Glass, I.; Horike-Pyne, M.; Kim, M.; Leppig, K. A.; McLaughlin, I. J.; Ogawa, J.; Rosenthal, E. A.; Sheppeard, S.; Sherman, S. M.; Strohbehn, S.; Yuen, A. L.; Reh, T. A.; Byers, P. H.; Bamshad, M. J.; Hisama, F. M.; Jarvik, G. P.; Sancak, Y.; Dipple, K. M.; Stergachis, A. B.
10.1101/2023.09.26.559521 — genetics — Posted on 2023-09-27
738 The oxytocin-modulated brain circuit that synchronizes heart rate with breathing
Buron, J. G.; Linossier, A. A.; Gestreau, C.; Schaller, F.; Tyzio, R.; Felix, M.-S.; Matarazzo, V.; Thoby-Brisson, M.; Muscatelli, F.; Menuet, C.
10.1101/2023.09.26.559512 — neuroscience — Posted on 2023-09-27
741 Nanoconnectivity: a quantitative approach to examine the structural complexity of the brain
Turegano-Lopez, M.; de las Pozas, F.; Santuy, A.; Rodriguez, J.-R.; Defelipe, J.; Merchan-Perez, A.
10.1101/2023.09.26.559505 — neuroscience — Posted on 2023-09-27
742 Absolute number of three populations of interneurons and GABAergic synapses in the human hippocampus
Takacs, V.; Papp, P.; Orosz, A.; Bardoczi, Z.; Zsoldos, T.; Watanabe, M.; Magloczky, Z.; Gombas, P.; Freund, T. F.; Nyiri, G.
10.1101/2023.09.26.559559 — neuroscience — Posted on 2023-09-27
743 Single-cell multi-omics map of human foetal blood in Down's Syndrome
Marderstein, A. R.; De Zuani, M.; Xue, H.; Bezney, J.; Wong, S.; Coorens, T. H. H.; Montgomery, S. B.; Cvejic, A.
10.1101/2023.09.25.559431 — genomics — Posted on 2023-09-27
745 The genomic landscape of metallic color variation in ground beetles
Weng, Y.-M.; Kavahaugh, D. H.; Rubio-Perez, B.; Salman, J.; Kats, M. A.; Schoville, S. D.
10.1101/2023.09.25.559374 — evolutionary biology — Posted on 2023-09-26
747 Gut microbial genomes with paired isolates from China signify probiotic and cardiometabolic effects
Huang, P.; Dong, Q.; Wang, Y.; Tian, Y.; Wang, S.; Zhang, C.; Yu, L.; Tian, F.; Gao, X.; Guo, H.; Yi, S.; Li, M.; Liu, Y.; Zhang, Q.; Lu, W.; Wang, G.; Yang, B.; Cui, S.; Hua, D.; Wang, X.; Jiao, Y.; Liu, L.; Deng, Q.; Ma, B.; Wu, T.; Zou, H.; CGMR Consortium, ; Shi, J.; Zhang, H.; Fan, D.; Sheng, Y.; Zhao, j.; Tang, L.; Zhang, H.; Sun, W.; Chen, W.; Kong, X.; Chen, L.; Zhai, Q.
10.1101/2023.09.25.559444 — microbiology — Posted on 2023-09-26
749 Replication-dead gammaherpesvirus vaccine protects against acute replication, reactivation from latency, and lethal challenge in mice
Bland, W. A.; Owens, S. M.; McEvoy, K.; Hogan, C. H.; Boccuzzi, L.; Kirillov, V.; Khairallah, C.; Sheridan, B. S.; Forrest, J. C.; Krug, L. T.
10.1101/2023.09.26.559621 — microbiology — Posted on 2023-09-26
750 Inhibition of Neisseria gonorrhoeae complement-mediated killing during acute gonorrhoea is dependent upon the IgG2:IgG3 antibody ratio
McKeand, S. A.; Faustini, S. E.; Cook, A.; Kennett, N.; Drayson, M. T.; Cunningham, A. F.; Henderson, I. R.; Ross, J. D. C.; Cole, J. A.; Rossiter-Pearson, A. E.
10.1101/2023.09.26.558794 — microbiology — Posted on 2023-09-26
754 Progressive community, biogeochemical and evolutionary remodeling of the soil microbiome underpins long-term desert ecosystem restoration
Chen, Q.; Yuan, M.; Jiang, L.; Wei, X.; Liu, Z.; Peng, C.; Huang, Z.; Tang, D.; Wu, X.; Sun, J.; Liu, Q.; Zhu, X.; Gao, P.; Huang, L.; Wang, M.; Jiang, M.; Jiang, C.
10.1101/2023.09.26.559499 — microbiology — Posted on 2023-09-26
759 Antagonism of kappa opioid receptors accelerates the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion
Flores, A. J.; Bartlett, M. J.; Seaton, B. T.; Samtani, G.; Sexauer, M. R.; Weintraub, N. C.; Siegenthaler, J. R.; Lu, D.; Heien, M. L.; Porreca, F.; Sherman, S. J.; Falk, T.
10.1101/2023.07.31.551112 — neuroscience — Posted on 2023-09-26
761 Bacterial antiviral defense pathways encode eukaryotic-like ubiquitination systems
Chambers, L. R.; Ye, Q.; Cai, J.; Gong, M.; Ledvina, H. E.; Zhou, H.; Whiteley, A. T.; Suhandynata, R. T.; Corbett, K. D.
10.1101/2023.09.26.559546 — biophysics — Posted on 2023-09-26
762 Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity
Zheng, L.; Yang, T.; Guo, H.; Qi, C.; Lu, Y.; Xiao, H.; Gao, Y.; Liu, Y.; Yang, Y.; Zhou, M.; Nguyen, H.; Zhu, Y.; Sun, F.; Zhang, C.-Y.; Ji, X.
10.1101/2023.09.25.559159 — biochemistry — Posted on 2023-09-26
764 Activation-induced shift in nutrient preference and function-specific nutrient dependence in human neutrophils
Britt, E. C.; Qing, X.; Votava, J. A.; Lika, J.; Wagner, A.; Shen, S.; Arp, N. L.; Khan, H.; Schieke, S. M.; Fletcher, C. D.; Huttenlocher, A.; Fan, J.
10.1101/2023.09.25.559385 — biochemistry — Posted on 2023-09-26
766 Pervasive GxE interactions shape adaptive trajectories and the exploration of the phenotypic space in artificial selection experiments
Desbiez-Piat, A.; Ressayre, A.; MARCHADIER, E.; Noly, A.; Remoue, C.; Vitte, C.; Belcram, H.; Bourgais, A.; Galic, N.; Le Guilloux, M.; Tenaillon, M. I.; Dillmann, C.
10.1101/2023.01.13.523786 — evolutionary biology — Posted on 2023-09-26
767 Sediment source and dose influence the larval performance of the threatened coral Orbicella faveolata
Serrano, X.; Rosales, S. M.; Miller, M. W.; Palacio-Castro, A. M.; Williamson, O. M.; Gomez, A.; Baker, A. C.
10.1101/2023.09.22.559035 — ecology — Posted on 2023-09-26
768 Oct4 redox sensitivity potentiates reprogramming and differentiation
Shen, Z.; Wu, Y.; Mana, A.; Evason, K. J.; Chandrasekharan, M. B.; Tantin, D.
10.1101/2023.02.21.529404 — molecular biology — Posted on 2023-09-26
769 Neural signatures of natural behavior in socializing macaques
Testard, C.; Tremblay, S.; Parodi, F.; DiTullio, R. W.; Acevedo-Ithier, A.; Gardiner, K.; Kording, K. P.; Platt, M.
10.1101/2023.07.05.547833 — neuroscience — Posted on 2023-09-26
775 The temporal dynamics of lncRNA Firre-mediated epigenetic and transcriptional regulation
Much, C.; Lasda, E.; Pereira, I. T.; Vallery, T. K.; Ramirez, D.; Lewandowski, J.; Dowell, R. D.; Smallegan, M. J.; Rinn, J. L.
10.1101/2022.05.15.492001 — genomics — Posted on 2023-09-26
776 Genomic signatures of adaptation in native lizards exposed to human-introduced fire ants
Assis, B. A.; Sullivan, A. P.; Marciniak, S.; Bergey, C. M.; Garcia, V.; Szpiech, Z. A.; Langkilde, T.; Perry, G. H.
10.1101/2023.09.24.559217 — evolutionary biology — Posted on 2023-09-26
777 Intra and interspecific diversity in a tropical plant clade alter herbivory and ecosystem resilience
Grele, A.; Massad, T. J.; Uckele, K. A.; Dyer, L.; Antonini, Y.; Braga, L.; Forister, M. L.; Sulca-Garro, L.; Kato, M.; Lopez, H. G.; Nascimento, A. R.; Parchman, T.; Simbana, W. R.; Smilanich, A. M.; Stireman, J. O.; Tepe, E. J.; Walla, T.; Richards, L. A.
10.1101/2023.03.05.531210 — ecology — Posted on 2023-09-26
779 Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1
Dingal, P. C. D. P.; Carte, A. N.; Montague, T. G.; Lim Suan, M. B.; Schier, A. F.
10.1101/2021.04.25.441333 — developmental biology — Posted on 2023-09-26
780 An enhancer RNA recruits MLL1 to regulate transcription of Myb
Kim, J.; Diaz, L. F.; Miller, M. J.; Leadem, B.; Krivega, I.; Dean, A.
10.1101/2023.09.26.559528 — cell biology — Posted on 2023-09-26
781 Antidepressants stimulate lipoprotein(a) macropinocytosis via serotonin-enhanced cell surface binding
Deo, N.; Siddiqui, H.; Madani, G.; Rutledge, M.; Williams, M.; McCormick, S. P.; Redpath, G. M. I.
10.1101/2021.03.26.437114 — cell biology — Posted on 2023-09-26
783 Prolonged delays in human microbiota transmission after a controlled antibiotic perturbation
Xue, K. S.; Walton, S. J.; Goldman, D. A.; Morrison, M. L.; Verster, A. J.; Parrott, A. B.; Yu, F. B.; Neff, N.; Rosenberg, N. A.; Ross, B. D.; Petrov, D.; Huang, K. C.; Good, B. H.; Relman, D.
10.1101/2023.09.26.559480 — microbiology — Posted on 2023-09-26
784 Rolling the evolutionary dice: Neisseria commensals as proxies for elucidating the underpinnings of antibiotic resistance mechanisms and evolution in human pathogens
Frost, K. M.; Charron-Smith, S. L.; Cotsonas, T. C.; Dimartino, D. C.; Eisenhart, R. C.; Everingham, E. T.; Holland, E. C.; Imtiaz, K.; Kornowicz, C. J.; Lenhard, L. E.; Lynch, L. H.; Moore, N. P.; Phadke, K.; Reed, M. L.; Smith, S. R.; Ward, L. L.; Wadsworth, C. B.
10.1101/2023.09.26.559611 — microbiology — Posted on 2023-09-26
787 The impact of phage and phage resistance on microbial community dynamics
Alseth, E. O.; Custodio, R.; Sundius, S. A.; Kuske, R. A.; Brown, S. P.; Westra, E. R.
10.1101/2023.09.26.559468 — microbiology — Posted on 2023-09-26
789 Mechanism for Vipp1 spiral formation, ring biogenesis and membrane repair
Naskar, S.; Merino, A.; Espadas, J.; Singh, J.; Roux, A.; Colom, A.; Low, H. H.
10.1101/2023.09.26.559607 — microbiology — Posted on 2023-09-26
790 Diet-induced obesity impacts influenza disease severity and transmission dynamics in ferrets
Meliopoulos, V. A.; Honce, R.; Livingston, B.; Hargest, V.; Freiden, P.; Lazure, L.; Brigleb, P. H.; Karlsson, E. A.; Tillman, H.; Allen, E. K.; Boyd, D.; Thomas, P.; Schultz-Cherry, S.
10.1101/2023.09.26.558609 — microbiology — Posted on 2023-09-26
792 Dynamic ventral disc contraction is necessary for Giardia attachment and host pathology
Nosala, C.; Hagen, K. D.; Guest, S. L.; Hilton, N. A.; Mueller, A.; Laue, M.; Klotz, C.; Aebischer, A.; Dawson, S. C.
10.1101/2023.07.04.547600 — microbiology — Posted on 2023-09-26
794 Using synchronized brain rhythms to bias memory-guided decisions
Stout, J. J.; George, A. E.; Kim, S.; Hallock, H. L.; Griffin, A. L.
10.1101/2023.04.02.535279 — neuroscience — Posted on 2023-09-26
797 High plasticity of ribosomal DNA organization in budding yeast
Jiang, S.; Cai, Z.; Wang, Y.; Zeng, C.; Zhang, J.; Yu, W.; Su, C.; Zhao, S.; Chen, Y.; Shen, Y.; Ma, Y.; Cai, Y.; Dai, J.
10.1101/2023.09.26.559284 — synthetic biology — Posted on 2023-09-26
798 LanTERN: a fluorescent sensor that specifically binds lanthanides
Jones, E. M.; Su, Y.; Sander, C.; Justman, Q. A.; Springer, M.; Silver, P. A.
10.1101/2023.09.26.559553 — synthetic biology — Posted on 2023-09-26
800 Mating system is associated with seed phenotypes upon loss of RNA-directed DNA Methylation in Brassicaceae
Dew-Budd, K. J.; Chow, H. T.; Kendall, T.; David, B. C.; Rozelle, J. A.; Mosher, R. A.; Beilstein, M. A.
10.1101/2023.07.03.547469 — plant biology — Posted on 2023-09-26
801 Molecular tuning of sea anemone stinging
He, L. S.; Qi, Y.; Allard, C. A.; Valencia-Montoya, W. A.; Krueger, S. P.; Weir, K.; Seminara, A.; Bellono, N. W.
10.1101/2023.06.15.545144 — physiology — Posted on 2023-09-26
803 Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable Interaction with CTBP2
Pastoors, D.; Havermans, M.; Mulet-Lazaro, R.; Brian, D.; Noort, W.; Grasel, J.; Hoogenboezem, R.; Smeenk, L.; Demmers, J. A.; Enver, T.; Groen, R. W.; Bindels, E.; Delwel, R.
10.1101/2023.07.11.548358 — cancer biology — Posted on 2023-09-26
804 An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing
Li, Z.; Zhang, B.; Chan, J. J.; Tabatabaeian, H.; Tong, Q. Y.; Chew, X. H.; Fan, X.; Driguez, P.; Chan, C.; Cheong, F.; Wang, S.; Siew, B. E.; Tan, I. J.-W.; Lee, K. Y.; Lieske, B.; Cheong, W.-K.; Kappei, D.; Tan, K.-K.; Gao, X.; Tay, Y.
10.1101/2023.04.21.536771 — cancer biology — Posted on 2023-09-26
805 Multiscale effects of perturbed translation dynamics inform antimalarial design
Anton, L.; Cheng, W.; Haile, M.; Cobb, D. W.; Zhu, X.; Han, L.; Li, E.; Nair, A.; Lee, C. L.; Ke, H.; Zhang, G.; Doud, E. H.; Ho, C.-M.
10.1101/2023.09.03.556115 — biophysics — Posted on 2023-09-26
806 Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain
Small, G. I.; Federova, O.; Olinares, P. D. B.; Chandanani, J.; Banerjee, A.; Choi, Y. J.; Molina, H.; Chait, B.; Darst, S. A.; Campbell, E. A.
10.1101/2023.09.25.558837 — biophysics — Posted on 2023-09-26
807 A novel bivalent interaction mode underlies a non-catalytic mechanism for Pin1-mediated Protein Kinase C regulation
Chen, X.-R.; Dixit, K.; Yang, Y.; McDermott, M. I.; Imam, H. T.; Bankaitis, V. A.; Igumenova, T. I.
10.1101/2023.09.18.558341 — biophysics — Posted on 2023-09-26
808 RCoV19: A One-stop Hub for SARS-CoV-2 Genome Data Integration, Variants Monitoring, and Risk Pre-warning
Li, C.; Ma, L.; Zou, D.; Zhang, R.; Bai, X.; Li, L.; Wu, G.; Huang, T.; Zhao, W.; Jin, E.; Bao, Y.; Song, S.
10.1101/2023.09.24.558358 — bioinformatics — Posted on 2023-09-26
810 Using a function-first "scout fragment"-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes
Ramsey, J. R.; Shelton, P. M. M.; Heiss, T. K.; Olinares, P. D. B.; Vostal, L. E.; Soileau, H.; Grasso, M.; Warrington, S.; Adaniya, S.; Miller, M.; Sun, S.; Huggins, D. J.; Myers, R. W.; Chait, B. T.; Vinogradova, E. V.; Kapoor, T. M.
10.1101/2023.09.25.559391 — biochemistry — Posted on 2023-09-26
811 Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation
Ward, J. A.; Romartinez-Alonso, B.; Kay, D. F.; Bellamy-Carter, J.; Thurairajah, B.; Basran, J.; Kwon, H.; Leney, A. C.; Macip, S.; Roversi, P.; Muskett, F. W.; Doveston, R. G.
10.1101/2023.09.26.559467 — biochemistry — Posted on 2023-09-26
812 Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space
Lolicato, F.; Steringer, J.; Saleppico, R.; Beyer, D.; Fernandez-Sobaberas, J.; Unger, S.; Klein, S.; Riegerova, P.; Schmitt, X. J.; Kaptan, S.; Wegehingel, S.; Mueller, H.-M.; Freund, C.; Hof, M.; Sachl, R.; Chlanda, P.; Vattulainen, I.; Nickel, W.
10.1101/2023.04.12.536539 — biochemistry — Posted on 2023-09-26
814 Chromosome-scale Genome Assembly of the West Indian Fruit Fly Anastrepha obliqua (Diptera: Tephritidae)
Sim, S. B.; Congrains, C.; Velasco-Cuervo, S. M.; Corpuz, R. L.; Kauwe, A. N.; Scheffler, B.; Geib, S. M.
10.1101/2023.09.22.559041 — genomics — Posted on 2023-09-26
815 Muscle cell atrophy induced by miR-155-5p reveals molecular targets in skeletal muscle disorders
Lopes, L. O.; Cury, S. S.; de Moraes, D.; Oliveira, J. S.; de Oliveira, G.; Cabral-Marques, O.; Fernandez, G. J.; Hirata, M. H.; WANG, D.-Z.; Dal-Pai-Silva, M.; Carvalho, R.; Freire, P. P.
10.1101/2023.09.21.558746 — genomics — Posted on 2023-09-26
816 When paleontology meets genomics: complete mitochondrial genomes of two saber-toothed cats' species (Felidae: Machairodontinae)
Rodrigues-Oliveira, I. H.; Batista da Silva, I.; Rodrigues Rocha, R.; Silva Soares, R. A.; Menegidio, F. B.; Garcia, C.; Pasa, R.; Kavalco, K. F.
10.1101/2023.09.14.557696 — genomics — Posted on 2023-09-26
819 Cladosporium species detoxify multiple water micropollutants of emerging concern using diverse strategies
Leth, M. L.; Tang, K.; Sorensen, T.; Andersen, A. J.; Helix-Nielsen, C.; Andersen, B.; Frisvad, J.; Sondergaard, T. E.; Andersen, H. R.; Abou Hachem, M.
10.1101/2023.09.25.559271 — microbiology — Posted on 2023-09-26
820 Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised mice
Teixeira, J. E.; Gasonoo, M.; Miller, P.; Ajiboye, J.; Cameron, A. C.; Stebbins, E.; Campbell, S. D.; Griggs, D. W.; Spangenberg, T.; Meyers, M. J.; Huston, C. D.
10.1101/2023.09.26.559556 — microbiology — Posted on 2023-09-26
822 Antifungal efficacy of natural antiseptic products against Candida auris
Wu, W.-G.; Luk, K. S.; Hung, M.-F.; Tsang, W.-Y.; Lee, K.-P.; Lam, B. H.-S.; Cheng, K.-L.; Cheung, W.-S.; Tang, H.-L.; To, W.-K.
10.1101/2023.09.22.559057 — microbiology — Posted on 2023-09-26
823 Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10
Lopez-Ayllon, B. D.; Marin, S.; Farinas Fernandez, M.; Garcia-Garcia, T.; Fernandez-Rodriguez, R.; de Lucas-Rius, A.; Redondo, N.; Mendoza-Garcia, L.; Foguet, C.; Grigas, J.; Calvet, A.; Villalba, J. M.; Rodriguez Gomez, M. J.; Megias, D.; Mandracchia, B.; Luque, D.; Lozano, J. J.; Calvo, C.; Thomson, T. M.; Garrido, J. J.; Cascante, M.; Montoya, M.
10.1101/2023.09.26.559506 — immunology — Posted on 2023-09-26
824 Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons
Truex, N. L.; Mohapatra, S.; Melo, M.; Rodriguez, J.; Li, N.; Abraham, W.; Sementa, D.; Touti, F.; Keskin, D. B.; Wu, C. J.; Irvine, D. J.; Gomez-Bombarelli, R.; Pentelute, B. L.
10.1101/2023.08.22.554289 — immunology — Posted on 2023-09-26
827 Tetraspanin CD81 promotes leukemia stem cell function and represents a new therapeutic vulnerability in acute myeloid leukemia
Gonzales, F.; Peyrouze, P.; Boyer, T.; Guihard, S.; Sevrin, F.; LAURENT, D.; Plesa, A.; Barthelemy, A.; Bongiovanni, A.; Pottier, N.; PREUDHOMME, C.; DUPLOYEZ, N.; Berthon, C.; ROUMIER, C.; CHEOK, M.
10.1101/2023.09.20.558656 — cancer biology — Posted on 2023-09-26
828 Quantitative Assessment of Morphological Changes in Lipid Droplets and Lipid-Mito Interactions with Aging in Brown Adipose
Crabtree, A.; Neikirk, K.; Whiteside, A.; McKenzie, J.; Vue, Z.; Vang, L.; Owens, T. C.; Oliver, A.; Zeleke, F.; Beasley, H. K.; Garza-Lopez, E.; Scudese, E.; Koh, A.; Navarro, S.; Lam, J.; Kirk, B.; Mungai, M.; Sweetwyne, M. T.; Koh, H.-J.; Zaganjor, E.; Damo, S. M.; Gaddy, J. A.; Williams, C.; McReynolds, M.; Marshall, A. G.; Hinton, A.
10.1101/2023.09.23.559135 — biophysics — Posted on 2023-09-26
829 An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics
Celaj, A.; Gao, A. J.; Lau, T. T. Y.; Holgersen, E. M.; Lo, A.; Lodaya, V.; Cole, C. B.; Denroche, R. E.; Spickett, C.; Wagih, O.; Pinheiro, P. O.; Vora, P.; Mohammadi-Shemirani, P.; Chan, S.; Nussbaum, Z.; Zhang, X.; Zhu, H.; Ramamurthy, E.; Kanuparthi, B.; Iacocca, M.; Ly, D.; Kron, K.; Verby, M.; Cheung-Ong, K.; Shalev, Z.; Vaz, B.; Bhargava, S.; Yusuf, F.; Samuel, S.; Alibai, S.; Baghestani, Z.; He, X.; Krastel, K.; Oladapo, O.; Mohan, A.; Shanavas, A.; Bugno, M.; Bogojeski, J.; Schmitges, F.; Kim, C.; Grant, S.; Jayaraman, R.; Masud, T.; Deshwar, A.; Gandhi, S.; Frey, B. J.
10.1101/2023.09.20.558508 — bioinformatics — Posted on 2023-09-26
830 Expanding the DNA editing toolbox: novel lambda integrase variants targeting microalgal and human genome sequences.
Wei, S. J.; Siddiqui, A. A.; Yi, L. S.; Kannan, S.; Peter, S.; Yingying, Z.; Verma, C.; Droge, P.; Ghadessy, J. F.
10.1101/2023.09.22.559039 — bioengineering — Posted on 2023-09-26
832 "Tranq-Dope" Overdose and Mortality: Lethality Induced by Fentanyl and Xylazine
Smith, M.; Biancorosso, S.; Camp, J.; Hailu, S.; Johansen, A.; Morris, M.; Carlson, H.
10.1101/2023.09.25.559379 — pharmacology and toxicology — Posted on 2023-09-26
833 Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke
Zheng, S.; Banerji, R.; LeBourdais, R.; Zhang, S.; Dubois, E.; O'Shea, T. M.; Nia, H.
10.1101/2023.09.25.559368 — biophysics — Posted on 2023-09-26
835 The genomic landscape of metallic color variation in ground beetles
Weng, Y.-M.; Kavahaugh, D. H.; Schoville, S. D.; Kats, M. A.; Salman, J.; Rubio-Perez, B.
10.1101/2023.09.25.559374 — evolutionary biology — Posted on 2023-09-26
836 Resuscitating Sleeping Beauties: reviving a six-hundred-year-old amoeba and endosymbiont.
Hasni, I.; Tall, M. L.; Le Bailly, M.; Colson, P.; Levasseur, A.; Raoult, D.; La Scola, B.; Drancourt, M.
10.1101/2023.09.22.558946 — microbiology — Posted on 2023-09-26
837 A suite of engineered mice for interrogating psychedelic drug actions
Chiu, Y.-t.; Deutch, A.; Wang, W.; Schmitz, G. P.; Huang, K.; Kocak, D.; Lorach, P.; Bowye, K.; Liu, B.; Sciaky, N.; Hua, K.; Chen, C.; Mott, S.; Niehaus, J.; DiBerto, J.; English, J.; Walsh, J.; Scherrer, G.; Herman, M.; Wu, Z.; Wetsel, W. C.; Roth, B. L.
10.1101/2023.09.25.559347 — neuroscience — Posted on 2023-09-26
841 Context-aware single-cell multiome approach identified cell-type specific lung cancer susceptibility genes
Long, E.; Yin, J.; Shin, J. H.; Li, Y.; Kane, A.; Patel, H.; Luong, T.; Xia, J.; Han, Y.; Byun, J.; Zhang, T.; Zhao, W.; Landi, M. T.; Rothman, N.; Lan, Q.; Chang, Y. S.; Yu, F.; Amos, C.; Shi, J.; Lee, J. G.; Kim, E. Y.; Choi, J.
10.1101/2023.09.25.559336 — genomics — Posted on 2023-09-26
842 Harnessing the endogenous Type I-C CRISPR-Cas system for genome editing in Bifidobacterium breve
Han, X.; Chang, L.; Chen, H.; Zhao, j.; Tian, F.; Ross, R. P.; Stanton, C.; van Sinderen, D.; Chen, W.; Yang, B.
10.1101/2023.09.25.559376 — molecular biology — Posted on 2023-09-26
844 Pro-resolution lipid mediator maresin-1 ameliorates inflammation, promotes neuroprotection, and prevents disease progression in experimental models of multiple sclerosis
Zahoor, I.; Nematullah, M.; Ahmed, M. E.; Fatma, M.; Mir, S.; Ayasolla, K.; Cerghet, M.; Palaniyandi, S.; Mao-Draayer, Y.; Rattan, R.; Giri, S.
10.1101/2023.09.25.559216 — neuroscience — Posted on 2023-09-26
847 The ghost of selection past: evolution and conservation relevance of the kakapo color polymorphism
Urban, L.; Santure, A. W.; Uddstrom, L.; Digby, A.; Vercoe, D.; Eason, D.; Crane, J.; Kakapo Recovery Team, ; Wylie, M. J.; Davis, T.; LeLec, M. F.; Guhlin, J.; Poulton, S.; Slate, J.; Alexander, A.; Fuentes-Cross, P.; Dearden, P. K.; Gemmell, N. J.; Azeem, F.; Weyland, M.; Schwefel, H. G. L.; van Oosterhout, C.; Morales, H. E.
10.1101/2023.09.25.559367 — genomics — Posted on 2023-09-26
849 WITHDRAWN: Complement C3-dependent glutamatergic synapse elimination in the developing hippocampus is region- and synapse-specific
Salter, E. W.; Lei, G.; Choi, S.-L.; Ralph, L. T.; Zhang, L.; Jin, F.; Kadia, A.; Wang, J.; Georgiou, J.; Collingridge, G. L.
10.1101/2020.05.20.106930 — neuroscience — Posted on 2023-09-26
851 From buds to shoots: Insights into grapevine development from the Witch's Broom bud sport
Ritter, E. J.; Cousins, P.; Quigley, M.; Kile, A.; Raju, S. K. K.; Chitwood, D. H.; Niederhuth, C.
10.1101/2023.09.25.559343 — plant biology — Posted on 2023-09-26
852 The impact of size on middle-ear sound transmission in elephants, the largest terrestrial mammal
O'Connell-Rodwell, C. E.; Berezin, J. L.; Dharmarajan, A.; Ravicz, M. E.; Hu, Y.; Guan, X.; O'Connor, K. N.; Puria, S.
10.1101/2023.09.25.559337 — physiology — Posted on 2023-09-26
857 PanEffect: A pan-genome visualization tool for variant effects in maize
Andorf, C. M.; Haley, O. C.; Hayford, R. K.; Portwood, J. L.; Sen, S.; Cannon, E. K.; Gardiner, J. M.; Woodhouse, M. R.
10.1101/2023.09.25.559155 — bioinformatics — Posted on 2023-09-26
860 CellPolaris: Decoding Cell Fate through Generalization Transfer Learning of Gene Regulatory Networks
Feng, G.; Qin, X.; Zhang, J.; Huang, W.; Zhang, Y.; Cui, W.; Li, S.; Chen, Y.; Liu, W.; Tian, Y.; Liu, Y.; Dong, J.; Xu, P.; Man, Z.; Liu, G.; Liang, Z.; Jiang, X.; Yang, X.; Wang, P.; Yang, G.; Wang, H.; Wang, X.; Tong, M.-H.; Zhou, Y.; Zhang, S.; Chen, Y.; Wang, Y.; Li, X.
10.1101/2023.09.25.559244 — bioinformatics — Posted on 2023-09-26
863 Genome-wide family prediction unveils molecular mechanisms underlying the regulation of agronomic traits in Urochloa ruziziensis
Martins, F. B.; Aono, A. H.; Moraes, A. d. C. L.; Ferreira, R. C. U.; Vilela, M. d. M.; Pessoa-Filho, M.; Motta, M. R.; Simeao, R. M.; de Souza, A. P.
10.1101/2023.09.25.559305 — genetics — Posted on 2023-09-26
864 Massive lateral gene transfer under strain coexistence in the gut
Frazao, N.; Seixas, E.; Barreto, H.; Mischler, M.; Guleresi, D.; Gordo, I.
10.1101/2023.09.25.559333 — evolutionary biology — Posted on 2023-09-26
865 Sediment source and dose influence the larval performance of the threatened coral Orbicella faveolata
Serrano, X.; Rosales, S. M.; Miller, M. W.; Palacio-Castro, A. M.; Williamson, O. M.; Gomez, A.; Baker, A. C.
10.1101/2023.09.22.559035 — ecology — Posted on 2023-09-26
866 Deep learning to extract the meteorological by-catch of wildlife cameras
Alison, J.; Payne, S.; Alexander, J. M.; Bjorkman, A. D.; Clarke, V. R.; Gwate, O.; Huntsaar, M.; Iseli, E.; Lenoir, J.; Mann, H. M. R.; Steenhuisen, S.-L.; Hoye, T. T.
10.1101/2023.09.25.558780 — ecology — Posted on 2023-09-26
869 Glacier extinction homogenizes functional diversity
Khelidj, N.; Caccianiga, M.; Cerabolini, B. E.; Tampucci, D.; Losapio, G.
10.1101/2023.09.25.559332 — ecology — Posted on 2023-09-26
870 The grass that built the Central Highland of Madagascar: environmental niches and morphological diversity of Loudetia simplex
Almary, T. O. M.; White, J.; Rasaminirina, F.; Razanatsoa, J.; Lehmann, C.; Rakotoarinivo, M.; Ralimanana, H.; Vorontsova, M. S.; Tiley, G. P.
10.1101/2023.09.25.559324 — ecology — Posted on 2023-09-26
871 SHIP1 modulation and proteome characterization of microglia
Ahat, E.; Shi, Z.; Chu, S.; Bui, H. H.; Mason, E. R.; Soni, D. M.; Roth, K. D.; Chalmers, M. J.; Oblak, A. L.; Zhang, J.; Gutierrez, J. A.; Richardson, T.
10.1101/2023.09.25.559310 — neuroscience — Posted on 2023-09-26
872 Neuronal aging is associated with declined autophagy caused by reduced functionality of cGAS-STING signaling
Passarella, S.; Brandes, K.; Dankert, E.; Cavalli, P.; Kroeger, A.; Dieterich, D. C.; Landgraf, P.
10.1101/2023.09.25.559304 — neuroscience — Posted on 2023-09-26
873 Oxytocin, but not vasopressin, decreases willingness to harm others by promoting moral emotions of guilt and shame
Zheng, X.; Wang, J.; Yang, X.; Xu, L.; Becker, B.; Sahakian, B. J.; Robbins, T.; Kendrick, K. M. M.
10.1101/2023.09.25.559242 — neuroscience — Posted on 2023-09-26
874 Suppression of HIV and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters
Cui, B. C.; Aksenova, M.; Sikirzhytskaya, A.; Odhiambo, D.; Korunova, E.; Sikirzhytski, V.; Ji, H.; Altomare, D.; Broude, E.; Frizzell, N.; Booze, R.; Wyatt, M. D.; Shtutman, M.
10.1101/2023.09.25.559154 — neuroscience — Posted on 2023-09-26
875 Differential mutation rates in plant meristematic layers
Amundson, K. R.; Marimuthu, M. P. A.; Nguyen, O.; Sarika, K.; DeMarco, I. J.; Phan, A.; Henry, I. M.; Comai, L.
10.1101/2023.09.25.559363 — plant biology — Posted on 2023-09-26
876 IRAK1 is a critical mediator of low molecular weight hyaluronic acid-induced stemness in high-grade serous ovarian cancer
Standing, D.; Dandawate, P.; Gunewardena, S.; Covarrubias-Zambrano, O.; Roby, K. F.; Khabele, D.; Jewell, A.; Tawfik, O.; Bossmann, S. H.; Godwin, A. K.; Weir, S. J.; Jensen, R. A.; Anant, S.
10.1101/2023.09.25.559366 — cancer biology — Posted on 2023-09-26
877 A Novel Subtype of Myeloproliferative Neoplasms Driven by a MYC-Alarmin Axis
Vincelette, N. D.; Yu, X.; Kuykendall, A. T.; Moon, J.; Su, S.; Cheng, C.-H.; Sammut, R.; Razabdouski, T. N.; Nguyen, H. V.; Eksioglu, E. A.; Chan, O.; Al Ali, N.; Patel, P. C.; Lee, D. H.; Nakanishi, S.; Ferreira, R. B.; Mo, Q.; Cory, S.; Lawrence, H. R.; Zhang, L.; Murphy, D. J.; Komrokji, R. S.; Lee, D.; Kaufmann, S. H.; Cleveland, J. L.; Yun, S.
10.1101/2023.09.25.559138 — cancer biology — Posted on 2023-09-26
878 Organelle landscape analysis using a multi-parametric particle-based method
Kurikawa, Y.; Koyama-Honda, I.; Igarashi, K.; Tamura, N.; Koike, S.; Mizushima, N.
10.1101/2023.09.25.559448 — cell biology — Posted on 2023-09-26
880 Nuclear lamin A-associated proteins are required for centromere assembly
Landeros, A.; Wallace, D.; Rahi, A.; Magdongon, C.; Suraneni, P.; Amin, M.; Chakraborty, M.; Adam, S.; Foltz, D.; Varma, D.
10.1101/2023.09.25.559341 — cell biology — Posted on 2023-09-26
882 The Topological Properties of the Protein Universe
Madsen, C. D.; Barbensi, A.; Zhang, S. Y.; Ham, L.; David, A.; Pires, D. E. V.; Stumpf, M. P. H.
10.1101/2023.09.25.559443 — bioinformatics — Posted on 2023-09-26
884 Co-evolution of spheroid fluidization and mechanical fracture in a morphogenic cascade
Wu, S. K.; Ho, C. Z.; Sun, F.; Lou, Y.; Huang, C. B.-X.; Xiao, J.; Shagirov, M.; Yow, I.; Chin, J. F. L.; Verma, S.; Yap, A.; Lin, Y.; Hiraiwa, T.; Low, B. C.
10.1101/2023.09.25.559247 — cell biology — Posted on 2023-09-26
886 The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies
Goo, L.; Kikawa, C.; Cartwright-Acar, C. H.; Stuart, J. B.; Contreras, M.; Levoir, L. M.; Evans, M. J.; Bloom, J. D.
10.1101/2023.09.13.557606 — microbiology — Posted on 2023-09-26
888 Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist
Maruyama, Y.; Ohsawa, Y.; Suzuki, T.; Yamauchi, Y.; Ohno, K.; Inoue, H.; Yamamoto, A.; Hayashi, M.; Okuhara, Y.; Muramatsu, W.; Namiki, K.; Miyauchi, M.; Miyao, T.; Hagiwara, N.; Ishikawa, T.; Horie, K.; Hayama, M.; Akiyama, N.; Hirokawa, T.; Akiyama, T.
10.1101/2023.05.08.539826 — pharmacology and toxicology — Posted on 2023-09-26
890 EPIGENETIC MODULATION VIA THE C-TERMINAL TAIL OF H2A.Z
Imre, L.; Nanasi, P.; Benhamza, I.; Enyedi, K. N.; Mocsar, G.; Bosire, R.; Hegedus, E.; Niaki, E. F.; Csoti, A.; Darula, Z.; Csosz, E.; Poliska, S.; Scholtz, B.; Mezo, G.; Bacso, Z.; Timmers, M. H. T.; Kusakabe, M.; Balazs, M.; Vamosi, G.; Ausio, J.; Cheung, P.; Toth, K.; Tremethick, D.; Harata, M.; Szabo, G.
10.1101/2021.02.22.432230 — cell biology — Posted on 2023-09-26
891 New insights into functional divergence and adaptive evolution of uncultured bacteria in anammox community by complete genome-centric analysis
Wang, Y.-C.; Mao, Y.; Fu, H.-M.; Wang, J.; Weng, X.; Liu, Z.-H.; Xu, X.-W.; Yan, P.; Fang, F.; Guo, J.-S.; Shen, Y.; Chen, Y.-P.
10.1101/2023.08.15.553441 — microbiology — Posted on 2023-09-26
892 Microbially-catalyzed conjugation of GABA and tyramine to bile acids
Mullowney, M.; Fiebig, A.; Schnizlein, M.; McMillin, M.; Koval, J.; Rubin, D.; Dalal, S.; Sogin, M.; Chang, E.; Sidebottom, A.; Crosson, S.
10.1101/2023.09.25.559407 — microbiology — Posted on 2023-09-26
894 DiffSegR: An RNA-Seq data driven method for differential expression analysis using changepoint detection
Liehrmann, A.; Delannoy, E.; Launay-Avon, A.; Gilbault, E.; Loudet, O.; Castandet, B.; Rigaill, G.
10.1101/2023.06.05.543691 — bioinformatics — Posted on 2023-09-26
895 Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation
Schmassmann, P.; Roux, J.; Dettling, S.; Hogan, S.; Shekarian, T.; Martins, T. A.; Ritz, M.-F.; Herter, S.; Bacac, M.; Hutter, G.
10.1101/2022.06.17.496574 — cancer biology — Posted on 2023-09-26
896 Metabolic plasticity of serine metabolism is crucial for cGAS/STING-signalling and innate immune response to viral infections in the gut
Becker, B.; Wottawa, F.; Bakr, M.; Koncina, E.; Mayr, L.; Kugler, J.; Yang, G.; Windross, S. J.; Neises, L.; Mishra, N.; Harris, D.; Tran, F.; Welz, L.; Schwaerzler, J.; Banki, Z.; Stengel, S. T.; Ito, G.; Kroetz, C.; Coleman, O.; Jaeger, C.; Haller, D.; Paludan, S. R.; Blumberg, R.; Kaser, A.; Cicin-Sain, L.; Schreiber, S.; Letellier, E.; Adolph, T. E.; Rosenstiel, P.; Meiser, J.; Aden, K.
10.1101/2022.05.17.492340 — cell biology — Posted on 2023-09-26
899 Adaptive Functions of Structural Variants in Human Brain Development
Ding, W.; Li, X.; Zhang, J.; Ji, M.; Zhang, M.; Zhong, X.; Cao, Y.; Liu, X.; Li, C.; Xiao, C.; Wang, J.; Li, T.; Yu, Q.; Mo, F.; Zhang, B.; Qi, J.; Yang, J.-C.; Qi, J.; Tian, L.; Xu, X.; Peng, Q.; Zhou, W.-Z.; Liu, Z.; Fu, A.; Zhang, X.; Zhang, J.-j.; Sun, Y.; Hu, B.; An, N. A.; Zhang, L.; Li, C.-Y.
10.1101/2023.09.25.558917 — evolutionary biology — Posted on 2023-09-26
903 Comparative Interactome Analysis of α-arrestin Families in Human and Drosophila
Lee, K.-T.; Pranoto, I. K.; Kim, S.-Y.; Choi, H.-J.; To, N. B.; Chae, H.; Lee, J.-Y.; Kim, J.-E.; Kwon, Y. V.; Nam, J.-W.
10.1101/2023.06.11.544486 — cell biology — Posted on 2023-09-26
905 Regulation of the mouse ventral tegmental area by melanin-concentrating hormone
Spencer, C. D.; Miller, P. A.; Williams-Ikhenoba, J. G.; Nikolova, R. G.; Chee, M. J.
10.1101/2023.09.25.559435 — neuroscience — Posted on 2023-09-26
906 White matter tract microstructure, macrostructure, and associated cortical gray matter morphology across the lifespan
Schilling, K.; Chad, J. A.; Chamberland, M.; Nozais, V.; Rheault, F.; Archer, D. B.; Li, M.; Gao, Y.; Cai, L. Y.; Del'Acqua, F.; Newton, A.; Moyer, D.; Gore, J. C.; Lebel, C.; Landman, B. A.
10.1101/2023.09.25.559330 — neuroscience — Posted on 2023-09-26
907 BackWards - Unveiling the Brain's Topographic Organization of Paraspinal Sensory Input
Guekos, A.; Cole, D. M.; Doerig, M. A.; Staempfli, P.; Schibli, L.; Schuetz, P. A.; Schweinhardt, P.; Meier, M. L.
10.1101/2022.08.05.502912 — neuroscience — Posted on 2023-09-26
908 Microfluidic interfaces for chronic bidirectional access to the brain.
Marcigaglia, S.; De Plus, R.; Vandendriessche, C.; Cuypers, M.-L.; Cools, J.; Hoffman, L.; Vandenbroucke, R.; Dewilde, M.; Haesler, S.
10.1101/2023.09.22.558790 — neuroscience — Posted on 2023-09-26
910 Characterization of the zebrafish gabra1sa43718/sa43718 germline loss of function allele confirms a function for Gabra1 in motility and nervous system development.
Paz, D.; Reyes-Nava, N. G.; Pinales, B. E.; Perez, I.; Gil, C. B.; Gonzales, A. V.; Grajeda, B.; Estevao, I. L.; Ellis, C. C.; Quintana, A. M.
10.1101/2023.01.27.525860 — developmental biology — Posted on 2023-09-25
912 Quantifying decision-making in dynamic, continuously evolving environments
Ruesseler, M.; Weber, L. A.; Marshall, T. R.; O'Reilly, J. X.; Hunt, L. T.
10.1101/2022.08.18.504278 — neuroscience — Posted on 2023-09-25
913 Programmed Cell Death Modifies Neural Circuits and Tunes Intrinsic Behavior
Kochersberger, A.; Torkashvand, M. M.; Lee, D.; Baskoylu, S.; Sengupta, T.; Koonce, N.; Emerson, C.; Patel, N. V.; Colon-Ramos, D.; Flavell, S. W.; Horvitz, H. R.; Venkatachalam, V.; Hammarlund, M.
10.1101/2023.09.11.557249 — neuroscience — Posted on 2023-09-25
914 Astrocytic Gapjinc (TMEM43) modulates gap junction networks by facilitating transjunctional potentials
Jang, M. W.; Kim, K. J.; Lim, J.; Kim, D.; Park, Y. M.; KIM, T. Y.; Roh, W. S.; Han, Y.-E.; Won, J.; Lee, J.-H.; Shin, E.; Han, A.-r.; Kim, H. M.; Han, K.-S.; Lee, C. J.
10.1101/2022.11.08.515259 — neuroscience — Posted on 2023-09-25
915 Neural signatures of natural behavior in socializing macaques
Testard, C.; Tremblay, S.; Parodi, F.; DiTullio, R. W.; Acevedo-Ithier, A.; Gardiner, K.; Kording, K. P.; Platt, M.
10.1101/2023.07.05.547833 — neuroscience — Posted on 2023-09-25
918 The Geometric Evolution of Aortic Dissections: Predicting Surgical Success using Fluctuations in Integrated Gaussian Curvature
Khabaz, K.; Pugar, J.; Sankary, S.; Yuan, K.; Kim, J.; Kang, J.; Nguyen, N.; Cao, K.; Pierce, N.; Lee, C. J.; Kindlmann, G.; Milner, R.; Pocivavsek, L.
10.1101/2022.09.19.508582 — bioengineering — Posted on 2023-09-25
919 NatB-dependent acetylation protects procaspase-8 from UBR4-mediated degradation and is required for full induction of the extrinsic apoptosis pathway
Guedes, J. P.; Boyer, J. B.; Elurbide, J.; Carte, B.; Redeker, V.; Sago, L.; Meinnel, T.; Corte-Real, M.; Giglione, C.; Aldabe, R.
10.1101/2023.09.25.559278 — biochemistry — Posted on 2023-09-25
920 Enhancers associated with unstable RNAs are rare in plants
Mcdonald, B. R.; Picard, C.; Brabb, I. M.; Savenkova, M. I.; Schmitz, R. J.; Jacobsen, S. E.; Duttke, S. H.
10.1101/2023.09.25.559415 — genomics — Posted on 2023-09-25
924 Microbially-catalyzed conjugation of GABA and tyramine to bile acids
Mullowney, M.; Fiebig, A.; Schnizlein, M.; McMillin, M.; Koval, J.; Rubin, D.; Dalal, S.; Sogin, M.; Chang, E.; Sidebottom, A.; Crosson, S.
10.1101/2023.09.25.559407 — microbiology — Posted on 2023-09-25
925 Cellular RNA interacts with MAVS to promote antiviral signaling
Gokhale, N. S.; Somfleth, K.; Thompson, M. G.; Sam, R. K.; Marciniak, D. M.; Chu, L. H.; Park, M.; Dvorkin, S.; Oberst, A.; Horner, S. M.; Ong, S.-E.; Gale, M.; Savan, R.
10.1101/2023.09.25.559083 — immunology — Posted on 2023-09-25
926 Repetitive Spreading Depolarization induces the activation of cell differentiation, synaptic plasticity and neuroprotective pathways.
Dell'Orco, M.; Weisend, J. E.; Perrone-Bizzozero, N. I.; Carlson, A. P.; Morton, R. A.; Linsenbardt, D. N.; Shuttleworth, C. W.
10.1101/2023.02.27.530317 — neuroscience — Posted on 2023-09-25
927 Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia
Nementzik, L. R.; Thumbadoo, K. M.; Murray, H. C.; Gordon, D.; Yang, S.; Blair, I. P.; Turner, C.; Faull, R. L.; Curtis, M. A.; McLean, C.; Nicholson, G. A.; Swanson, M. E.; Scotter, E. L.
10.1101/2023.02.10.527924 — neuroscience — Posted on 2023-09-25
928 A deep learning classification task for brain navigation during functional ultrasound imaging
Lambert, T.; Brunner, C.; Kil, D.; Wuyts, R.; D'Hondt, E.; Montaldo, G.; Urban, A.
10.1101/2022.03.18.484747 — neuroscience — Posted on 2023-09-25
929 Root Walker: an automated pipeline for large scale quantification of early root growth responses at high spatial and temporal resolution
Platre, M. P.; Mehta, P.; Halvorson, Z.; zhang, L.; Matias, G. F.; Brent, L.; Faizi, K.; Goulding, C.; Busch, W.
10.1101/2022.11.16.516796 — plant biology — Posted on 2023-09-25
931 Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon
Thieme, M.; Minadakis, N.; Himber, C.; Keller, B.; Xu, W.; rutowicz, K.; Matteoli, C.; Boehrer, M.; Rymen, B.; Laudencia-Chingcuanco, D.; Vogel, J. P.; Sibout, R.; Stritt, C.; Blevins, T.; Roulin, A. C.
10.1101/2023.09.25.559196 — genomics — Posted on 2023-09-25
932 The MUC19 gene in Denisovans, Neanderthals, and Modern Humans: An Evolutionary History of Recurrent Introgression and Natural Selection
Villanea, F. A.; Peede, D.; Kaufman, E. J.; Anorve-Garibay, V.; Dillon, K. E. W.; Zeloni, R.; Marnetto, d.; Moorjani, P.; Jay, F.; Valdmanis, P. N.; Avila-Arcos, M. C.; Huerta-Sanchez, E.
10.1101/2023.09.25.559202 — evolutionary biology — Posted on 2023-09-25
934 Ancient genomic linkage couples metabolism with erythroid development
Preston, A. E.; Frost, J. N.; Badat, M.; Teh, M.; Armitage, A. E.; Norfo, R.; Wideman, S. K.; Hanifi, M.; White, N.; Roy, N.; Ghesquiere, B.; Babbs, C.; Kassouf, M.; Davies, J.; Hughes, J.; Beagrie, R.; Higgs, D.; Drakesmih, H.
10.1101/2023.09.25.558944 — cell biology — Posted on 2023-09-25
936 Shedding Light on the D1-Like Receptors: A Fluorescence-Based Toolbox for Visualization of the D1 and D5 Receptors
Rosier, N.; Moennich, D.; Nagl, M.; Schihada, H.; Sirbu, A.; Konar, N.; Reyes-Resina, I.; Navarro, G.; Franco, R.; Kolb, P.; Annibale, P.; Pockes, S.
10.1101/2023.09.25.559386 — molecular biology — Posted on 2023-09-25
937 Matrix selection for the visualization of small molecules and lipids in brain tumors using untargeted MALDI-TOF mass spectrometry imaging
Lu, T.; Freytag, L.; Narayana, V. K.; Moore, Z.; Oliver, S. J.; Valkovic, A.; Nijagal, B.; Peterson, A.; De Souza, D. P.; McConville, M. J.; Whittle, J. R.; Best, S. A.; Freytag, S.
10.1101/2023.09.25.559427 — molecular biology — Posted on 2023-09-25
939 ENHANCED EFFICIENCY OF RNA-GUIDED CAS12a VERSUS CAS9 TRANSGENE KNOCK-IN AND ACTIVITY AT A SCHISTOSOMA MANSONI GENOME SAFE HARBOR
Moescheid, M. F.; Wisitphongpun, P.; Mann, V. H.; Quack, T.; Grunau, C.; Grevelding, C. G.; Tanno, W. I.; Brindley, P. J.
10.1101/2023.09.12.557428 — molecular biology — Posted on 2023-09-25
941 Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike
Wang, Q.; Guo, Y.; Liu, L.; Schwanz, L. T.; Li, Z.; Ho, J.; Zhang, R. M.; Iketani, S.; Yu, J.; Huang, Y.; Qu, Y.; Valdez, R.; Lauring, A. S.; Gordon, A.; Wang, H. H.; Liu, L.; Ho, D. D.
10.1101/2023.09.24.559214 — microbiology — Posted on 2023-09-25
942 A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system
Costacurta, F.; Dodaro, A.; Bante, D.; Schoeppe, H.; Sprenger, B.; Moghadasi, S. A.; Fleischmann, J.; Pavan, M.; Bassani, D.; Menin, S.; Rauch, S.; Krismer, L.; Sauerwein, A.; Heberle, A.; Rabensteiner, T.; Ho, J.; Harris, R. S.; Stefan, E.; Schneider, R.; Kaserer, T.; Moro, S.; von Laer, D.; Heilmann, E.
10.1101/2023.09.22.558628 — microbiology — Posted on 2023-09-25
943 Swine influenza A virus isolates containing the pandemic H1N1 origin matrix gene elicit greater disease in the murine model
Curran, S. J.; Griffin, E. F.; Ferreri, L.; Kyriakis, C. S.; Howerth, E. W.; Perez, D. R.; Tompkins, S. M.
10.1101/2023.09.25.559220 — microbiology — Posted on 2023-09-25
944 Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics
Stribling, W.; Hall, L. R.; Powell, A.; Harless, C.; Martin, M. J.; Corey, B. W.; Snesrud, E.; Ong, A.; Maybank, R.; Stam, J.; Bartlett, K.; Jones, B. T.; Preston, L. N.; Lane, K. F.; Thompson, B.; Young, L. M.; Kwak, Y. I.; Barsoumian, A. E.; Markelz, A.-E.; Kiley, J. L.; Cybulski, R. J.; Bennett, J. W.; Mc Gann, P. T.; Lebreton, F.
10.1101/2023.07.24.550326 — microbiology — Posted on 2023-09-25
945 Immune Correlates of Hyperglycemia and Vaccination in a Non-human Primate Model of Long-COVID
Palmer, C. S.; Perdios, C.; Abdel-Mohsen, M.; Mudd, J.; Datta, P.; Maness, N.; Lehmicke, G.; Golden, N.; Hellmer, L.; Coyne, C.; Moore Green, K.; Midkiff, C.; Williams, K.; Tiburcio, R.; Fahlberg, M.; Boykin, K.; Kenway, C.; Russell-Lodrigue, K.; Bohm, R.; Blair, R. V.; Dufour, J.; Fischer, T.; Saied, A.; Rappaport, J.
10.1101/2023.09.22.559019 — immunology — Posted on 2023-09-25
946 Neutrophil efferocytosis reprograms mitochondrial metabolism to switch alveolar macrophages to a pro-resolution phenotype at the cost of bacterial control
Better, J.; Wetstein, M.; Estiri, M.; Malainou, C.; Ferrero, M. R.; Langelage, M.; Kuznetsova, I.; Vazquez-Armendariz, I.; Kimmig, L.; Mansouri, S.; Savai, R.; Wilhelm, J.; Alexopoulos, I.; Sommer, N.; Herold, S.; Matt, U.
10.1101/2023.03.07.528464 — immunology — Posted on 2023-09-25
948 Multi-modal profiling of biostabilized human skin modules reveals a coordinated ecosystem response to injected mRNA-1273 COVID-19 vaccine.
Scholaert, M.; Peries, M.; Braun, E.; Martin, J.; Serhan, N.; Loste, A.; Bruner, A.; Basso, L.; Chaput, B.; Merle, E.; Descargues, P.; Pages, E.; Gaudenzio, N.
10.1101/2023.09.22.558940 — bioengineering — Posted on 2023-09-25
950 Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies
Medina-Munoz, H. C.; Kofman, E.; Jagannatha, P.; Boyle, E. A.; Yu, T.; Jones, K. L.; Mueller, J. R.; Lykins, G. D.; Doudna, A. T.; Park, S. S.; Blue, S. M.; Ranzau, B. L.; Kohli, R. M.; Komor, A. C.; Yeo, G. W.
10.1101/2023.09.25.558915 — genomics — Posted on 2023-09-25
952 Survey of white-footed mice in Connecticut, USA reveals low SARS-CoV-2 seroprevalence and infection with divergent betacoronaviruses
Earnest, R.; Hahn, A. M.; Feriancek, N. M.; Brandt, M.; Filler, R. B.; Zhao, Z.; Breban, M. I.; Vogels, C. B. F.; Chen, N. F. G.; Koch, R. T.; Porzucek, A. J.; Sodeinde, A.; Garbiel, A.; Keanna, C.; Litwak, H.; Stuber, H. R.; Cantoni, J. L.; Pitzer, V. E.; Olarte Castillo, X. A.; Goodman, L. B.; Wilen, C. B.; Linske, M. A.; Williams, S. C.; Grubaugh, N. D.
10.1101/2023.09.22.559030 — ecology — Posted on 2023-09-25
953 Fluorescent Tools for Imaging and Ligand Screening of Dopamine D2-Like Receptors
Nagl, M.; Moennich, D.; Rosier, N.; Schihada, H.; Sirbu, A.; Konar, N.; Reyes-Resina, I.; Navarro, G.; Franco, R.; Kolb, P.; Annibale, P.; Pockes, S.
10.1101/2023.09.25.559398 — molecular biology — Posted on 2023-09-25
955 A gut meta-interactome map reveals modulation of human immunity by microbiome effectors
Young, V.; Dohai, B.; Hitch, T. C.; Hyden, P.; Weller, B.; Heusden, N. S.; Saha, D.; Macgregor, J. F.; Maseko, S. B.; Lin, C.-W.; Boujeant, M.; Choteau, S. A.; Ober, F.; Schwehn, P.; Rothballer, S.; Altmann, M.; Altmann, S.; Strobel, A.; Rothballer, M.; Tofaute, M. J.; Heinig, M.; Clavel, T.; Twizere, J.-C.; Vincentelli, R.; Boes, M.; Krappmann, D.; Falter, C.; Rattei, T.; Brun, C.; Zanzoni, A.; Falter-Braun, P.
10.1101/2023.09.25.559292 — microbiology — Posted on 2023-09-25
956 Species- and strain-effects in interferon, innate immunity, and barrier transcriptional response of microbiome interactions of 3D respiratory epithelial cultures
Horvath, M.; Yang, R.; Castaneda, D. C.; Callender, M.; Fleming, E.; Voigt, A.; Caldwell, R.; Fachi, J.; Di Luccia, B.; Scholar, Z.; Yu, P.; Salner, A.; Colonna, M.; Palucka, K.; Oh, J.
10.1101/2023.09.25.559418 — microbiology — Posted on 2023-09-25
958 Translation in a Box: Orthogonal Evolution in the Saccharomyces cerevisiae Mitochondrion
Rothschild-Mancinelli, B.; Alvarez-Carreno, C.; Guo, W.; Ito, C.; Costa, A.; Petrov, A. S.; Lobachev, K.; Williams, L. D.
10.1101/2023.04.28.538752 — synthetic biology — Posted on 2023-09-25
963 Convergent adaptation of true crabs (Decapoda: Brachyura) to a gradient of terrestrial environments
Wolfe, J. M.; Ballou, L.; Luque, J.; Watson-Zink, V. M.; Ahyong, S. T.; Barido-Sottani, J.; Chan, T.-Y.; Chu, K. H.; Crandall, K. A.; Daniels, S. R.; Felder, D. L.; Mancke, H.; Martin, J. W.; Ng, P. K. L.; Ortega-Hernandez, J.; Palacios Theil, E.; Pentcheff, N. D.; Robles, R.; Thoma, B. P.; Tsang, L. M.; Wetzer, R.; Windsor, A. M.; Bracken-Grissom, H. D.
10.1101/2022.12.09.519815 — evolutionary biology — Posted on 2023-09-25
965 Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe
Ristori, T.; Thuret, R.; Hooker, E.; Quicke, P.; Lanthier, K.; Ntumba, K.; Aspalter, I. M.; Uroz, M.; Herbert, S. P.; Chen, C. S.; Larrivee, B.; Bentley, K.
10.1101/2023.09.25.557123 — developmental biology — Posted on 2023-09-25
966 Unveiling the ultrastructural landscape of native extracellular matrix via lift-out cryo-FIBSEM and cryo-ET
Zens, B.; Faessler, F.; Hansen, J. M.; Hauschild, R.; Datler, J.; Hodirnau, V.-V.; Zheden, V.; Alanko, J.; Sixt, M.; Schur, F. K.
10.1101/2023.09.25.559261 — cell biology — Posted on 2023-09-25
967 Increased hippocampal epigenetic age in the Ts65Dn Mouse Model of Down Syndrome
Ravaioli, F.; Stagni, F.; Guidi, S.; Pirazzini, C.; Garagnani, P.; Silvani, A.; Zoccoli, G.; Bartesaghi, R.; Bacalini, M. G.
10.1101/2023.09.25.559272 — molecular biology — Posted on 2023-09-25
970 Activity-dependent development of the body's touch receptors
Santiago, C.; Sharma, N.; Africawala, N.; Siegrist, J.; Handler, A.; Tasnim, A.; Anjum, R.; Turecek, J.; Lehnert, B. P.; Renauld, S.; Nolan-Tamariz, M.; Iskols, M.; Magee, A. R.; Paradis, S.; Ginty, D. D.
10.1101/2023.09.23.559109 — neuroscience — Posted on 2023-09-25
973 CDK8/19 Inhibition Attenuates G1 Arrest Induced by BCR-ABL Antagonists and Accelerates Death of Chronic Myelogenous Leukemia Cells
Khamidullina, A. I.; Yastrebova, M. A.; Bruter, A. V.; Nuzhina, J. V.; Vorobyeva, N. E.; Khrustaleva, A. M.; Varlamova, E. A.; Tyakht, A. V.; Abramenko, Y. E.; Ivanova, E. S.; Zamkova, M. A.; Li, J.; Lim, C.-U.; Chen, M.; Broude, E. V.; Roninson, I. B.; Shtil, A. A.; Tatarskiy, V. V.
10.1101/2023.09.25.559286 — cancer biology — Posted on 2023-09-25
976 Amoeba Predation of Cryptococcus: A Quantitative and Population Genomic Evaluation of the Accidental Pathogen Hypothesis
Sauters, T. J. C.; Roth, C.; Murray, D.; Sun, S.; Floyd-Averette, A. J. C.; Onyishi, C. U.; May, R. C.; Heitman, J.; Magwene, P. M.
10.1101/2022.12.08.519367 — genomics — Posted on 2023-09-25
980 Fecal Virome of Coendou spinosus (Paraguaian Hairy Dwarf Porcupine)
Miranda, T. d. S.; de Matos, I. G.; D'arc, M.; Moreira, F. R. R.; Schiffler, F. B.; Cosentino, M. A. C.; Coimbra, A. d. L.; de Oliveira, T. H.; Mouta, R.; Medeiros, G.; Girardi, D. L.; Lima, M.; Wanderkoke, V.; Francisco, T. M.; Soffiati, F. L.; Ferreira, S. S.; Ruiz-Miranda, C. R.; Soares, M. A.; Andrade dos Santos, A. F.
10.1101/2023.09.24.559146 — microbiology — Posted on 2023-09-25
983 Adaptive brain changes to virtual lesions interfering with visual processing
Raffin, E.; Salamanca-Giron, R. F.; Huxlin, K. R.; Reynaud, O.; Mattera, L.; Martuzzi, R.; Hummel, F.
10.1101/2022.03.03.482512 — neuroscience — Posted on 2023-09-25
984 Glutamatergic Supramammillary Nucleus Neurons Respond to Threatening Stressors and Promote Active Coping
Escobedo, A.; Holloway, S.-A.; Votoupal, M.; Cone, A. L.; Skelton, H. E.; Legaria, A.; Ndiokho, I.; Floyd, T.; Kravitz, A. V.; Bruchas, M. R.; Norris, A. J.
10.1101/2022.09.22.507167 — neuroscience — Posted on 2023-09-25
990 Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus
Apaa, T.; Withers, A.; MacKenzie, L.; Staley, C. E.; Dessi, N.; Blanchard, A. M.; Bennett, M.; Bremner-Harrison, S.; Chadwick, E.; Hailer, F.; Harrison, S.; Lambin, X.; Loose, M.; Mathews, F.; Tarlinton, R. E.
10.1101/2023.04.28.538769 — microbiology — Posted on 2023-09-25
991 Online Bayesian Optimization of Nerve Stimulation
Wernisch, L.; Edwards, T.; Berthon, A.; Tessier-Lariviere, O.; Sarkans, E.; Stoukidi, M.; Fortier-Poisson, P.; Pinkney, M.; Thornton, M.; Hanley, C.; Lee, S.; Jennings, J.; Appleton, B.; Garsed, P.; Patterson, B.; Buttinger, W.; Gonshaw, S.; Jakopec, M.; Shunmugam, S.; Mamen, J.; Tukiainen, A.; Lajoie, G.; Armitage, O.; Hewage, E.
10.1101/2023.08.30.555315 — neuroscience — Posted on 2023-09-25
996 What makes the effect of protein mutations difficult to predict?
van der Flier, F. J.; Estell, D.; Pricelius, S.; Dankmeyer, L.; van Stigt Thans, S.; Mulder, H.; Otsuka, R.; Goedegebuur, F.; Lammerts, L.; Staphorst, D.; van Dijk, A. D. J.; de Ridder, D.; Redestig, H.
10.1101/2023.09.25.559319 — bioinformatics — Posted on 2023-09-25
997 scPipe: An extended preprocessing pipeline for comprehensive single-cell ATAC-Seq data integration in R/Bioconductor
Amarasinghe, S. L.; Yang, P.; Voogd, O.; Yang, H.; Du, M.; Su, S.; Brown, D. V.; Jabbari, J. S.; Bowden, R.; Ritchie, M. E.
10.1101/2023.09.25.559230 — bioinformatics — Posted on 2023-09-25
999 The NS1 protein of influenza B virus binds 5'-triphosphorylated dsRNA to suppress RIG-I activation and the antiviral innate immune response
Woltz, R.; Schweibenz, B.; Tsutakawa, S. E.; Zhao, C.; Ma, L.-C.; Shurina, B.; Hura, G. L.; John, R.; Vorobiev, S.; Gurla, S.; Solotchi, M.; Tainer, J. A.; Krug, R. M.; Patel, S. S.; Montelione, G. T.
10.1101/2023.09.25.559316 — biochemistry — Posted on 2023-09-25
1000 Widespread dissemination of ESBL-producing Salmonella enterica serovar Infantis exhibiting intermediate fluoroquinolone resistance and harboring blaCTX-M-65-positive pESI-like megaplasmids in Chile
Pina-Iturbe, A.; Diaz-Gavidia, C.; Alvarez, F. P.; Barron-Montenegro, R.; Alvarez-Espejo, D. M.; Garcia, P.; Solis, D.; Constenla-Albornoz, R.; Toro, M.; Olivares-Pacheco, J.; Reyes-Jara, A.; Meng, J.; Bell, R. L.; Moreno-Switt, A. I.
10.1101/2023.09.25.559306 — genomics — Posted on 2023-09-25
1004 Deacetylation by sirtuins is important for Aspergillus fumigatus pathogenesis and virulence
Wassano, N. S.; da Silva, G. B.; Reis, A. H.; Gerhardt, J. A.; Antoniel, E. P.; Akiyama, D. Y.; Rezende, C. P.; Neves, L. X.; Vasconcelos, E.; Figueiredo, F. L.; Almeida, F.; de Castro, P. A.; Pinzan, C. F.; Goldman, G.; Paes Leme, A. F.; Fill, T.; Moretti, N. S.; Damasio, A.
10.1101/2023.09.25.558961 — microbiology — Posted on 2023-09-25
1006 Calcineurin-dependent contributions to fitness in the opportunistic pathogen Candida glabrata
Pavesic, M. W.; Gale, A. N.; Nickels, T. J.; Harrington, A. A.; Bussey, M.; Cunningham, K. W.
10.1101/2023.09.25.559325 — microbiology — Posted on 2023-09-25
1007 Dopamine enhances multisensory responses in the dorsomedial striatum
Saez, M.; Alegre-Cortes, J.; Morgenstern, N. A.; Garcia-Frigola, C.; de la Torre-Martinez, R.; Reig, R.
10.1101/2023.09.25.559270 — neuroscience — Posted on 2023-09-25
1009 The microcephaly gene ASPM is required for the timely generation of human outer-radial glia progenitors by controlling mitotic spindle orientation
van Benthem, A.; Limame, R.; Piumatti, M.; Erkol, E.; Zaratin, M.; Tanaka, D.; Herpoel, A.; Bilheu, A.; van Berthem, H.; Nebreda, L.; Matthijs, G.; Keymolen, K.; Poovathingal, S.; Ditkowska, M.; Passemard, S.; Abramowicz, M.; Ledent, C.; Vanderhaeghen, P.
10.1101/2023.09.25.559314 — neuroscience — Posted on 2023-09-25
1011 Surface-engineered extracellular vesicles to modulate antigen-specific T cell expansion for cancer immunotherapy
Lyu, X.; Yamano, T.; Imai, S.; Le, T. V.; Bolidong, D.; Ueda, M.; Warashina, S.; Mukai, H.; Hayashi, S.; Matoba, K.; Nishino, T.; Hanayama, R.
10.1101/2023.09.25.559260 — bioengineering — Posted on 2023-09-25
1012 Activin E is a TGFβ ligand that signals specifically through activin receptor-like kinase 7.
Vestal, K. A.; Kattamuri, C.; Koyiloth, M.; Ongaro, L.; Howard, J. A.; Deaton, A.; Ticau, S.; Dubey, A.; Bernard, D. J.; Thompson, T. B.
10.1101/2023.09.25.559288 — biochemistry — Posted on 2023-09-25
1014 Assessing the role of mitonuclear interactions on mitochondrial function and organismal fitness in natural Drosophila populations
Bettinazzi, S.; Liang, J.; Rodriguez, E.; Bonneau, M.; Holt, R.; Whitehead, B.; Dowling, D.; Lane, N.; Camus, F.
10.1101/2023.09.25.559268 — evolutionary biology — Posted on 2023-09-25
1015 Isolation and quantification of bacterial membrane vesicles for quantitative metabolic studies using mammalian cell cultures
Wegner, A.; Kretschmer, M.; Mueller, J.; Otto, V.; Rodriguez, A. A.; Muesken, M.; Jahn, D.; Borrero-de Acuna, J. M.; Neumann-Schaal, M.; Henke, P.
10.1101/2023.09.25.559254 — cell biology — Posted on 2023-09-25
1017 iPSC-based modeling of helicase deficiency reveals impaired cell proliferation and increased apoptosis after NK cell lineage commitment
Seo, S.; Patil, S. L.; Ahn, Y.-O.; Armetta, J.; Hegewisch-Solloa, E.; Castillo, M.; Guilz, N. C.; Patel, A.; Corneo, B.; Borowiak, M.; Gunaratne, P.; Mace, E. M.
10.1101/2023.09.25.559149 — cell biology — Posted on 2023-09-25
1018 Class A capsid assembly modulator apoptotic elimination of hepatocytes with high HBV core antigen level in vivo is dependent on de novo core protein translation
Berke, J. M.; Tan, Y.; Sauviller, S.; Wu, D.-t.; Zhang, K.; Conceicao-Neto, N.; Blazquez-Moreno, A.; Kong, D.; Kukolj, G.; Li, C.; Zhu, R.; Najera, I.; Pauwels, F.
10.1101/2023.09.25.559252 — microbiology — Posted on 2023-09-25
1019 Improved CAR-T cell activity associated with increased mitochondrial function primed by galactose
Gross, G.; Alkaderi, S.; Itzhaki, O.; Aharony-Tevet, Y.; Ben Yosef, S.; Zenab, A.; Shbiro, L.; Toren, A.; Yardeni, T.; Jacoby, E.
10.1101/2023.09.23.559091 — immunology — Posted on 2023-09-25
1022 ATE1 activates ER-stress and UPR pathways in glioblastoma
Macedo-da-Silva, J.; Oba-Shinjo, S. M.; Rosa-Fernandes, L.; Soares, R. d. S.; Lerario, A. M.; Moretti, I. F.; Laurentino, T. d. S.; Cintra, R. C.; Marie, S. K. N.; Palmisano, G.
10.1101/2023.09.25.559258 — cancer biology — Posted on 2023-09-25
1030 Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
Adriaenssens, E.; Nguyen, T. N.; Sawa-Makarska, J.; Khuu, G.; Schuschnig, M.; Shoebridge, S.; Watts, E. M.; Csalyi, K. D.; Padman, B. S.; Lazarou, M.; Martens, S.
10.1101/2023.09.25.559255 — cell biology — Posted on 2023-09-25
1033 Association of homelessness and diet on the gut microbiome: A United States-Veteran Microbiome Project (US-VMP) study
Hoisington, A. J.; Stearns-Yoder, K. A.; Stamper, C. E.; Holliday, R.; Brostow, D. P.; Penzenik, M.; Forster, J. E.; Postolache, T. T.; Lowry, C. A.; Brenner, L. A.
10.1101/2023.09.22.559004 — microbiology — Posted on 2023-09-25
1034 A synthetic peptide mimic kills Candida albicans and synergistically prevents infection
Schaefer, S.; Vij, R.; Sprague, J. L.; Austermeier, S.; Dinh, H.; Judzewitsch, P. R.; Seemann, E.; Qualmann, B.; Cain, A. K.; Corrigan, N.; Gresnigt, M. S.; Boyer, C.; Lenardon, M. D.; Brunke, S.
10.1101/2023.09.25.559234 — microbiology — Posted on 2023-09-25
1035 Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells
Lazzerini Ospri, L.; Zhan, J.; Thomsen, M.; Wang, H.; Messanvi, F.; du Hoffmann, J.; Cravedi, K.; Chudasama, Y.; Zhao, H.; Hattar, S.; Komal, R.
10.1101/2023.09.22.556752 — neuroscience — Posted on 2023-09-25
1042 Online Bayesian Optimization of Nerve Stimulation
Wernisch, L.; Edwards, T.; Berthon, A.; Tessier-Lariviere, O.; Sarkans, E.; Stoukidi, M.; Fortier-Poisson, P.; Pinkney, M.; Thornton, M.; Hanley, C.; Lee, S.; Jennings, J.; Appleton, B.; Garsed, P.; Patterson, B.; Buttinger, W.; Gonshaw, S.; Jakopec, M.; Shunmugam, S.; Mamen, J.; Tukiainen, A.; Lajoie, G.; Armitage, O.; Hewage, E.
10.1101/2023.08.30.555315 — neuroscience — Posted on 2023-09-25
1044 High prevalence of haemosporidian parasites in Eurasian Jays
Schumm, Y. R.; Lederer-Ponzer, N.; Masello, J. F.; Quillfeldt, P.
10.1101/2023.06.20.545710 — pathology — Posted on 2023-09-25
1045 Single-cell mechanical analysis reveals viscoelastic similarities between normal and neoplastic brain cells
Onwudiwe, K.; Najera, J.; Holen, L.; Burchett, A. A.; Rodriguez, D.; Zarodniuk, M.; Siri, S.; Datta, M.
10.1101/2023.09.23.559055 — bioengineering — Posted on 2023-09-25
1048 Genomic signatures of adaptation in native lizards exposed to human-introduced fire ants
Assis, B. A.; Sullivan, A. P.; Marciniak, S.; Bergey, C. M.; Garcia, V.; Szpiech, Z. A.; Langkilde, T.; Perry, G. H.
10.1101/2023.09.24.559217 — evolutionary biology — Posted on 2023-09-25
1052 Long non-coding RNA TUG1 is down-regulated in Friedreich's ataxia.
Koka, M.; Li, H.; Akther, R.; Perlman, S.; Wong, D.; Fogel, B. L.; Lynch, D. R.; Chandran, V.
10.1101/2023.09.22.558879 — neuroscience — Posted on 2023-09-25
1057 The target gene regulatory network of miR-497 in angiosarcoma
Benton, A.; Terwilliger, E.; Moriarty, N. M.; Liu, B.; Murphy, A.; Maluvac, H.; Shu, M.; Gartenhaus, L. E.; Janson, N. D.; Pfeffer, C. M.; Utturkar, S. M.; Parkinson, E. I.; Lanman, N. A.; Hanna, J. A.
10.1101/2023.09.24.559218 — cancer biology — Posted on 2023-09-25
1059 Towards label-free non-invasive autofluorescence multispectral imaging for melanoma diagnosis
Knab, A.; Anwer, A. G.; Pedersen, B.; Handley, S.; Marupally, A. G.; Habibalahi, A.; Goldys, E. M.
10.1101/2023.09.25.559240 — biophysics — Posted on 2023-09-25
1060 OBIA: An Open Biomedical Imaging Archive
Jin, E.; Zhao, D.; Wu, G.; Zhu, J.; Wang, Z.; Wei, Z.; Zhang, S.; Wang, A.; Tang, B.; Chen, X.; Sun, Y.; Zhang, Z.; Zhao, W.; Meng, Y.
10.1101/2023.09.12.557281 — bioinformatics — Posted on 2023-09-25
1062 Increased deformations of aging bone marrow during physical activity is dispensable for cell mechanoresponse in bone analogs
Regner, A.; DeLeon, M.; Howard, S.; Gibbons, K.; Nesbitt, D.; Lujan, T.; Fitzpatrick, C.; Farach-Carson, M. C.; Wu, D.; Uzer, G.
10.1101/2023.09.24.559187 — bioengineering — Posted on 2023-09-24
1063 Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA
Finocchio, G.; Koopal, B.; Potocnik, A.; Heijstek, C.; Jinek, M.; Swarts, D. C.
10.1101/2023.09.23.559129 — biochemistry — Posted on 2023-09-25
1064 The type of DNA damage response after Decitabine treatment depends on the level of DNMT activity
Aumer, T.; Bergmayr, L.; Kartika, S.; Zeng, T.; Ge, Q.; Giorgio, G.; Daether, M.; Hess, A. J.; Michalakis, S.; Traube, F. R.
10.1101/2023.09.02.556017 — biochemistry — Posted on 2023-09-25
1066 The determinants of the rarity of nucleic and peptide short sequences in nature
Chantzi, N.; Mouratidis, I.; Mareboina, M.; Konnaris, M. A.; Montgomery, A.; Georgakopoulos-Soares, I.
10.1101/2023.09.24.559219 — genomics — Posted on 2023-09-25
1067 Hybridization and its impact on the ontogenetic allometry of skulls in macaques
Ito, T.; Kimura, R.; Wakamori, H.; Tanaka, M.; Tezuka, A.; Nagano, A. J.; Hamada, Y.; kawamoto, Y.
10.1101/2023.04.19.536293 — evolutionary biology — Posted on 2023-09-25
1069 A direct experimental test of Ohno's hypothesis
Mihajlovic, L.; Iyengar, B. R.; Baier, F.; Barbier, I.; Iwaszkiewicz, J.; Zoete, V.; Wagner, A.; Schaerli, Y.
10.1101/2023.09.25.559237 — evolutionary biology — Posted on 2023-09-25
1073 Longitudinal study of Chlamydia pecorum in a healthy Swiss cattle population
Loehrer, S.; Hagenbuch, F.; Marti, H.; Pesch, T.; Hässig, M.; Borel, N.
10.1101/2023.09.24.559209 — microbiology — Posted on 2023-09-24
1075 Adaptive immunity: from CRISPR to CRIHSP?
Niu, Z.; Wang, Y.; Xu, B.; Jin, X.; Ning, L.; Hao, Y.; Yan, Y.; Wang, M.; Zhu, W.; Zhi, L.; Guo, C.
10.1101/2023.09.25.559221 — immunology — Posted on 2023-09-25
1076 Autophagic cargo in Lewy bodies: are Lewy bodies a compartment for spatial protein quality control?
Conod, P.; Charlesworth, N.; Palmowski, P.; Porter, A.; Walker, L.; El-Agnaf, O. M. A.; Korolchuk, V. I.; Outeiro, T. F.; Erskine, D.
10.1101/2023.09.24.559164 — neuroscience — Posted on 2023-09-24
1078 Hierarchy in influence but not firing patterns among forelimb motor cortices
Saiki-Ishikawa, A.; Agrios, M.; Savya, S.; Forrest, A.; Sroussi, H.; Hsu, S.; Basrai, D.; Xu, F.; Miri, A.
10.1101/2023.09.23.559136 — neuroscience — Posted on 2023-09-24
1080 A developmentally defined population of neurons in the lateral septum controls responses to aversive stimuli
Turrero Garcia, M.; Tran, D. N.; Peterson, R. E.; Stegmann, S. K.; Hanson, S. M.; Reid, C. M.; Xie, Y.; Vu, S.; Harwell, C. C.
10.1101/2023.09.24.559205 — neuroscience — Posted on 2023-09-25
1081 A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
Bayati, A.; Ayoubi, R.; Aguila, A.; Zorca, C. E.; Han, C.; Banks, E.; Nguyen-Renou, E.; Luo, W.; shlaifer, i.; Del Cid-Pellitero, E.; Yaqubi, M.; Fon, E. A.; Stratton, J. A.; Durcan, T.; Nahirney, P.; McPherson, P. S.
10.1101/2023.05.29.542776 — neuroscience — Posted on 2023-09-25
1084 Chemotactic interactions drive migration of membraneless active droplets
Dindo, M.; Bevilacqua, A.; Soligo, G.; Monti, A.; Rosti, M.; Laurino, P.
10.1101/2023.04.25.538216 — biochemistry — Posted on 2023-09-25
1092 Embodiment in episodic memory through premotor-hippocampal coupling
Meyer, N. H.; Gauthier, B.; Stampacchia, S.; Boscheron, J.; Babo-Rebelo, M.; Potheegadoo, J.; Herbelin, B.; Lance, F.; Alvarez, V.; Franc, E.; Esposito, F.; Morais Lacerda, M.; Blanke, O.
10.1101/2023.09.23.559108 — neuroscience — Posted on 2023-09-24
1093 Psychedelic 5-HT2A receptor agonism: neuronal signatures and altered neurovascular coupling.
Padawer-Curry, J. A.; Snyder, A. Z.; Bice, A. R.; Wang, X.; Nicol, G. E.; McCall, J. G.; Siegel, J. S.; Bauer, A. Q.
10.1101/2023.09.23.559145 — neuroscience — Posted on 2023-09-24
1095 The invasive brown seaweed Rugulopteryx okamurae (Dictyotales, Ochrophyta) continues to expand: first record in Italy.
Bellisimo, G.; Altamirano, M.; Munoz, A. R.; De la Rosa, J.; Hung, T. H.; Rizzuto, G.; Vizzini, S.; Tomasello, A.
10.1101/2023.09.23.559131 — plant biology — Posted on 2023-09-24
1096 A redox-shifted fibroblast subpopulation emerges in the fibrotic lung.
Link, P. A.; Meridew, J. A.; Caporarello, N.; Gao, A. Y.; Peters, V.; Smith, G. B.; Rojas, M.; Tschumperlin, D. J.
10.1101/2023.09.23.559128 — pathology — Posted on 2023-09-24
1098 Serial dilution shapes genetic variation and defines conservation units in Asian elephants
Khan, A.; Sil, M.; Thekaekara, T.; Sinha, I.; Khurana, R.; Sukumar, R.; Ramakrishnan, U.
10.1101/2023.09.04.556173 — evolutionary biology — Posted on 2023-09-24
1099 Digitize your Biology! Modeling multicellular systems through interpretable cell behavior
Johnson, J. A. I.; Stein-O'Brien, G. L.; Booth, M.; Heiland, R.; Kurtoglu, F.; Bergman, D.; Bucher, E.; Deshpande, A.; Forjaz, A.; Getz, M.; Godet, I.; Lyman, M.; Metzcar, J.; Mitchell, J.; Raddatz, A.; Rocha, H. L.; Solorzano, J.; Sundus, A.; Wang, Y.; Gilkes, D. M.; Kagohara, L. T.; Kiemen, A. L.; Thompson, E. D.; Wirtz, D.; Wu, P.-H.; Zaidi, N.; Zheng, L.; Zimmerman, J. W.; Jaffee, E. M.; Chang, Y. H.; Coussens, L.; Gray, J.; Heiser, L. M.; Fertig, E. J.; Macklin, P.
10.1101/2023.09.17.557982 — systems biology — Posted on 2023-09-24
1100 ImAge: an imaging approach to quantitate aging and rejuvenation.
Alvarez-Kuglen, M.; Rodriguez, D.; Qin, H.; Ninomiya, K.; Fiengo, L.; Farhy, C.; Havas, A.; Hsu, W.-M.; Feng, G.-S.; Roberts, A.; Anderson, R. M.; Serrano, M.; Adams, P. D.; Sharpee, T. O.; Terskikh, A.
10.1101/2022.10.16.512441 — systems biology — Posted on 2023-09-24
1103 GET: a foundation model of transcription across human cell types
Fu, X.; Mo, S.; Shao, A.; Laurent, A.; Buendia, A.; Ferrando, A. A.; Ciccia, A.; Lan, Y.; Palomero, T.; Owens, D. M.; Xing, E. P.; Rabadan, R.
10.1101/2023.09.24.559168 — bioinformatics — Posted on 2023-09-24
1104 Single-cell mechanical analysis reveals viscoelastic similarities between normal and neoplastic brain cells
Onwudiwe, K.; Najera, J.; Holen, L.; Burchett, A. A.; Rodriguez, D.; Zarodniuk, M.; Siri, S.; Datta, M.
10.1101/2023.09.23.559055 — bioengineering — Posted on 2023-09-24
1106 Insect biomass of protected habitats under the impact of arable farming in Germany
Muehlethaler, R.; Koethe, S.; Hoerren, T.; Sorg, M.; Eichler, L.; Lehmann, G. U. C.
10.1101/2023.09.24.559203 — ecology — Posted on 2023-09-24
1109 Fecal Virome of Coendou spinosus (Paraguaian Hairy Dwarf Porcupine)
Miranda, T. d. S.; de Matos, I. G.; D'arc, M.; Moreira, F. R. R.; Schiffler, F. B.; Cosentino, M. A. C.; Coimbra, A. d. L.; de Oliveira, T. H.; Mouta, R.; Medeiros, G.; Girardi, D. L.; Lima, M.; Wanderkoke, V.; Francisco, T. M.; Soffiati, F. L.; Ferreira, S. S.; Ruiz-Miranda, C. R.; Soares, M. A.; Andrade dos Santos, A. F.
10.1101/2023.09.24.559146 — microbiology — Posted on 2023-09-24
1111 Short- and long-term high-fat diet exposure differentially alters phasic and tonic GABAergic signalling onto lateral orbitofrontal pyramidal neurons
Seabrook, L. T.; Peterson, C.; Noble, D.; Sobey, M.; Tayyab, T.; Kenney, T.; Judge, A. K.; Armstrong, M.; Lin, S.; Borgland, S. L.
10.1101/2023.05.08.539875 — neuroscience — Posted on 2023-09-24
1113 Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of neocortical projection neurons
Veeraraghavan, P.; Engmann, A. K.; Hatch, J. J.; Itoh, Y.; Nguyen, D.; Addison, T.; Macklis, J. D.
10.1101/2023.09.24.559186 — neuroscience — Posted on 2023-09-24
1114 Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice
de Assis, L. V.; Harder, L.; Lacerda, J. T.; Parsons, R.; Kaehler, M.; Cascorbi, I.; Nagel, I.; Rawashdeh, O.; Mittag, J.; Oster, H.
10.1101/2023.09.23.559037 — physiology — Posted on 2023-09-24
1115 SurvBal: Compositional Microbiome Balances for Survival Outcomes
Li, Y.; Lee, T.; Marin, K.; Hua, X.; Srinivasan, S.; Fredricks, D. N.; Lee, J. R.; Ling, W.
10.1101/2023.09.22.559069 — bioinformatics — Posted on 2023-09-24
1117 The Human Infertility Single-cell Testis Atlas (HISTA): An interactive molecular scRNA-Seq reference of the human testis.
Mahyari, E.; Vigh-Conrad, K. A.; Daube, C.; Lima, A. C.; Guo, J.; Carell, D.; Hotaling, J. M.; Aston, K. I.; Conrad, D.
10.1101/2023.09.23.558896 — bioinformatics — Posted on 2023-09-24
1119 Directional integration and pathway enrichment analysis for multi-omics data
Slobodyanyuk, M.; Bahcheli, A. T.; Klein, Z. P.; Bayati, M.; Strug, L. J.; Reimand, J.
10.1101/2023.09.23.559116 — bioinformatics — Posted on 2023-09-24
1120 Label-free 3-D molecular imaging of living tissues using Raman Spectral Projection Tomography
Stepula, E.; Walther, A. R.; Mehrotra, D.; Jensen, M.; Yuan, M. H.; Pedersen, S. V.; Gentleman, E.; Albro, M. B.; Hedegaard, M. A. B.; Bergholt, M. S.
10.1101/2023.09.23.559025 — bioengineering — Posted on 2023-09-24
1121 A 3D Printed Ventilated Perfused Lung Model Platform to Dissect the Lung's Response to Viral Infection in the Presence of Respiration
Derman, I. D.; Alioglu, M. A.; Banerjee, D.; Holton, S. E.; Klunk, D. N.; Nagamine, M.; Rizvi, S. H. A.; Mikacenic, C.; Celik, N.; Castaneda, D. C.; Prajakta, W.; Chen, P.; Schotsaert, M.; Peeples, M. E.; Palucka, K.; Koff, J.; Ozbolat, I. T.
10.1101/2023.09.24.559194 — bioengineering — Posted on 2023-09-24
1122 Characterizing Low-cost Registration for Photographic Images to Computed Tomography
Kim, M. E.; Lee, H. H.; Ramadass, K.; Gao, C.; Van Schaik, K.; Tkaczyk, E.; Spraggins, J. M.; Moyer, D. C.; Landman, B. A.
10.1101/2023.09.22.558989 — bioengineering — Posted on 2023-09-24
1127 Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover
Podolsky, M. J.; Kheyfets, B.; Pandey, M.; Beigh, A. H.; Yang, C. D.; Lizama Valenzuela, C.; Datta, R.; Wolters, P. J.; McManus, M.; Qi, L.; Atabai, K.
10.1101/2023.01.13.523943 — cell biology — Posted on 2023-09-24
1130 Recurrent activity within microcircuits of macaque dorsolateral prefrontal cortex tracks cognitive flexibility
Nolan, S. O.; Melugin, P. R.; Erickson, K. R.; Adams, W. R.; Farahbakhsh, Z. Z.; Mcgonigle, C. E.; Kwon, M. H.; Costa, V. D.; Lapish, C. C.; Hackett, T. A.; Cuzon Carlson, V. C.; Constantinidis, C.; Grant, K. A.; Siciliano, C. A.
10.1101/2023.09.23.559125 — neuroscience — Posted on 2023-09-24
1131 Virulence patterns of oat crown rust in Australia - season 2022
Henningsen, E. C.; Lewis, D. C.; Nguyen, D. T.; Sperschneider, J.; Kianian, S. F.; Stone, E.; Dodds, P.; Figueroa, M.
10.1101/2023.09.24.558528 — plant biology — Posted on 2023-09-24
1132 Cardiac disease diagnosis based on GAN in case of missing data
Chen, X.; Zhang, N.; Yang, X.; Wang, C.; na, q.; Luan, T.; Zhu, W.; Zhang, C.; Yang, C.
10.1101/2023.09.22.559043 — physiology — Posted on 2023-09-24
1133 Bio-inspired mineralization collagen induce fibrocartilage regeneration after tendon-bone injury by activating Gli1+Dkk3+ progenitor cells
Zhang, T.; Lei, T.; Han, J.; Zhang, R.; Shen, W.; Liu, Y.; Liao, Y.; He, Q.; Zhao, Y.; Zhang, X.; Yan, R.; He, Q.; Chen, Y.; Pan, H.; Wang, L.; Yin, W.; Ouyang, H.; Yin, Z.; Chen, X.
10.1101/2023.09.24.557863 — bioengineering — Posted on 2023-09-24
1136 A potential acoustic role for CFTR ion channel in conductive hearing loss
Liyanage, P.; Mun, K.; Carraro, G.; Ogden, H. L.; Huang, Y.; Lee, J.; Ramananda, Y.; Stripp, B. R.; Arora, K.; Salomonis, N.; Hunter, L. L.; Naren, A. P.
10.1101/2023.09.23.559053 — cell biology — Posted on 2023-09-24
1137 Activity-dependent development of the body's touch receptors
Santiago, C.; Sharma, N.; Africawala, N.; Siegrist, J.; Handler, A.; Tasnim, A.; Anjum, R.; Turecek, J.; Lehnert, B. P.; Renauld, S.; Nolan-Tamariz, M.; Iskols, M.; Magee, A. R.; Paradis, S.; Ginty, D. D.
10.1101/2023.09.23.559109 — neuroscience — Posted on 2023-09-24
1138 Endolysosomal dysfunction in radial glia progenitor cells leads to defective cerebral angiogenesis and compromised Blood-Brain Barrier integrity
Bassi, I.; Grunspan, M.; Hen, G.; Ravichandran, K. A.; Moshe, N.; Safriel, S. R.; Chen, A.; Ruiz De Almodovar, C.; Yaniv, K.
10.1101/2023.09.24.559123 — developmental biology — Posted on 2023-09-24
1139 Hand2 represses non-cardiac cell fates through chromatin remodeling at cis-regulatory elements
Komatsu, V.; Cooper, B. H.; Yim, P.; Chan, K.; Gong, W.; Wheatley, L.; Rohs, R.; Fraser, S. E.; Trinh, L. A.
10.1101/2023.09.23.559156 — developmental biology — Posted on 2023-09-24
1140 Differential effects of aneuploidy on growth and differentiation in human intestinal stem cells
Johnson, B. A.; Liu, A. Z.; Bi, T.; Dong, Y.; Li, T.; Zhou, D.; Narkar, A.; Wu, Y.; Sun, S.; Larman, T. C.; Zhu, J.; Li, R.
10.1101/2023.09.23.559117 — cell biology — Posted on 2023-09-24
1142 Exposure to aldehyde cherry e-liquid flavouring and its vape by-product disrupts pulmonary surfactant biophysical function
Martin, A.; Tempra, C.; Yu, Y. T.; Liekkinen, J.; Thakker, R.; Lee, H.; de Santos Moreno, B.; Vattulainen, I.; Rossios, C.; Javanainen, M.; Bernardino de la Serna, J.
10.1101/2023.09.22.558976 — pharmacology and toxicology — Posted on 2023-09-24
1143 Gene regulatory Networks Reveal Sex Difference in Lung Adenocarcinoma
Saha, E.; Ben-Guebila, M.; Fanfani, V.; Fischer, J.; Shutta, K. H.; Mandros, P.; DeMeo, D. L.; Quackenbush, J.; Lopes-Ramos, C. M.
10.1101/2023.09.22.559001 — cancer biology — Posted on 2023-09-24
1145 Evaluating and Improving Health Equity and Fairness of Polygenic Scores
Zhang, T.; Klei, L.; Liu, P.; Chouldechova, A.; Roeder, K.; G'Sell, M.; Devlin, B.
10.1101/2023.09.22.559051 — genetics — Posted on 2023-09-24
1150 Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis
Imoto, Y.; Xue, J.; Luo, L.; Raychaudhuri, S.; Itoh, K.; Ma, Y.; Craft, G. E.; Kwan, A. H.; Mackay, J.; Ha, T.; Watanabe, S.; Robinson, P. J.
10.1101/2023.09.21.558797 — cell biology — Posted on 2023-09-24
1151 Genome-wide association mapping of bruchid resistance loci in soybean
Mukuze, C.; Msiska, U. M.; Badji, A.; Obua, T.; Kweyu, S. V.; Nghituwamhata, S. N.; Rono, E. C.; Maphosa, M.; Kasule, F.; Tukamuhabwa, P.
10.1101/2023.09.22.559046 — plant biology — Posted on 2023-09-24
1158 Direct ionic stress sensing and mitigation by the transcription factor NFAT5
Khandwala, C. B.; Sarkar, P.; Schmidt, H. B.; Ma, M.; Kinnebrew, M.; Pusapati, G. V.; Patel, B. B.; Tillo, D.; Lebensohn, A. M.; Rohatgi, R.
10.1101/2023.09.23.559074 — cell biology — Posted on 2023-09-24
1159 The lipid Gb3 promotes germinal center B cell responses and anti-viral immunity
Sharma, P.; Zhang, X.; Ly, K.; Zhang, Y.; Hu, Y.; Ye, A.; Hu, J.; Kim, J. H.; Lou, M.; Wang, C.; Celuzza, Q.; Kondo, Y.; Furukawa, K.; Bundle, D.; Furukawa, K.; Alt, F.; Winau, F.
10.1101/2023.09.23.559132 — immunology — Posted on 2023-09-24
1160 Single-Cell Profiling Reveals a Naive-Memory Relationship between CD56bright and Adaptive Human Natural Killer Cells
Panjwani, M. K.; Grassmann, S.; Sottile, R.; Le Ludeuc, J.-B.; Kontopoulos, T.; van der Ploeg, K.; Sun, J. C.; Hsu, K. C.
10.1101/2023.09.23.559062 — immunology — Posted on 2023-09-24
1161 Caveolin-1 Autonomously Regulates Hippocampal Neurogenesis Via Mitochondrial Dynamics
Stephen, T. K. L.; Aponte Cofresi, L.; Quiroz, E.; Owusu-Ansah, K.; Ibrahim, Y.; Qualls, E.; Marshall, J.; Li, W.; Shetti, A.; Bonds, J. A.; Minshall, R. D.; Cologna, S. M.; Lazarov, O.
10.1101/2023.09.23.558792 — neuroscience — Posted on 2023-09-24
1162 Sequence characterization of T, Bip, and Phbw demonstrates the role of MYB-bHLH-WD40 complexes and temperature in common bean seed color pattern formation
Parker, T.; Bolt, T.; Williams, T.; Penmetsa, R. V.; Mulube, M.; Palkovic, A.; Jochua, C. N.; Rubio Wilhelmi, M. d. M.; Lo, S.; Bornhorst, G.; Tian, L.; Kamfwa, K.; Hokin, S.; Farmer, A.; Diepenbrock, C. H.; Gepts, P.
10.1101/2023.09.23.559151 — plant biology — Posted on 2023-09-24
1166 Rhythm Receptive Fields in Striatum of Mice Executing Complex Continuous Movement Sequences
Hirokane, K.; Nakamura, T.; Terashita, T.; Kubota, Y.; Hu, D.; Yagi, T.; Graybiel, A. M.; Kitsukawa, T.
10.1101/2023.09.23.559115 — neuroscience — Posted on 2023-09-23
1168 The representational geometry of emotional states in basolateral amygdala
O'Neill, P.-K.; Posani, L.; Meszaros, J.; Warren, P.; Schoonover, C. E.; Fink, A. J. P.; Fusi, S.; Salzman, C. D.
10.1101/2023.09.23.558668 — neuroscience — Posted on 2023-09-23
1174 Antifungal efficacy of natural antiseptic products against Candida auris
WU, W. G.; Luk, S.; HUNG, M. F.; TSANG, W. Y.; LEE, K. P.; LAM, B. H. S.; CHENG, K. L.; CHEUNG, W. S.; TANG, H. L.; To, W. K.
10.1101/2023.09.22.559057 — microbiology — Posted on 2023-09-23
1175 The lactonase BxdA mediates metabolic adaptation of maize root bacteria to benzoxazinoids
Thoenen, L.; Kreuzer, M.; Florean, M.; Mateo, P.; Zuest, T.; Giroud, C.; Rouyer, L.; Gfeller, V.; Notter, M.; Knoch, E.; Hapfelmeier, S.; Becker, C.; Schandry, N.; Robert, C.; Koellner, T.; Bruggmann, R.; Erb, M.; Schlaeppi, K.
10.1101/2023.09.22.559061 — microbiology — Posted on 2023-09-23
1176 RGS2 is an innate immune checkpoint for TLR4 and Gαq-mediated IFNγ generation and lung injury
Joshi, J. C.; Joshi, B.; Zhang, C.; Banerjee, S.; Vellingiri, V.; Raghunathrao, V. A. B.; Zhang, L.; Amin, R.; Song, Y.; Mehta, D.
10.1101/2023.09.22.559016 — immunology — Posted on 2023-09-23
1179 Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA
Finocchio, G.; Koopal, B.; Potocnik, A.; Heijstek, C.; Jinek, M.; Swarts, D. C.
10.1101/2023.09.23.559129 — biochemistry — Posted on 2023-09-23
1180 Single-Cell Analysis Reveals Cryptic Prophage Protease LfgB Protects Escherichia coli During Oxidative Stress by Cleaving Antitoxin MqsA
Fernandez-Garcia, L.; Gao, X.; Battisti, M.; Kirigo, J.; Garcia-Contreras, R.; Tomas, M.; Guo, Y.; Wang, X.; Wood, T. K.
10.1101/2023.09.23.559088 — molecular biology — Posted on 2023-09-23
1181 Local adaptation of a marine diatom is governed by genome-wide changes in diverse metabolic processes
Pinseel, E.; Ruck, E. C.; Nakov, T.; Jonsson, P. R.; Kourtchenko, O.; Kremp, A.; Pinder, M. I. M.; Roberts, W. R.; Sjoqvist, C.; Topel, M.; Godhe, A.; Hahn, M. W.; Alverson, A. J.
10.1101/2023.09.22.559080 — microbiology — Posted on 2023-09-23
1183 Synthetic control of actin polymerization and symmetry breaking in activeprotocells
Razavi, S.; Wong, F.; Abubaker-Sharif, B.; Matsubayashi, H. T.; Nakamura, H.; Sandoval, E.; Robinson, D. N.; Chen, B.; Liu, J.; Iglesias, P. A.; Inoue, T.
10.1101/2023.09.22.559060 — synthetic biology — Posted on 2023-09-23
1185 Structural insights into abscisic acid exporter AtABCG25
Xin, J.; Zhou, Y.; Qiu, Y.; Geng, H.; Wang, Y.; Song, Y.; Liang, J.; Yan, K.
10.1101/2023.09.22.559085 — plant biology — Posted on 2023-09-23
1187 Real-time pooled optical screening with single-cell isolation capability.
Karempudi, P.; Amselem, E.; Jones, D. L.; Khaji, Z.; Tenje, M.; Elf, J.
10.1101/2023.09.21.558600 — biophysics — Posted on 2023-09-23
1190 Pangenome graph layout by Path-Guided Stochastic Gradient Descent
Heumos, S.; Guarracino, A.; Schmelzle, J.-N. M.; Li, J.; Zhang, Z.; Hagmann, J.; Nahnsen, S.; Prins, P.; Garrison, E.
10.1101/2023.09.22.558964 — bioinformatics — Posted on 2023-09-23
1191 Cross-reactive macaque antibodies targeting marburgvirus glycoprotein induced by multivalent immunization
Janus, B. M.; Wang, R.; Cleveland, T. E.; Metcalf, M. C.; Lemmer, A. C.; Class, K.; Fuerst, T. R.; Ofek, G.
10.1101/2023.09.23.559102 — immunology — Posted on 2023-09-23
1192 Variability in the phytoplankton response to upwelling across an iron limitation mosaic within the California Current System
Lin, Y.; Torano, O.; Whitehouse, L.; Pierce, E.; Till, C. P.; Hurst, M.; Freiberger, R.; Mellett, T.; Maldonado, M. T.; Guo, J.; Sutton, M.; Zeitz, D.; Marchetti, A.
10.1101/2023.09.22.558967 — plant biology — Posted on 2023-09-23
1193 Validity and reliability of a new whole room indirect calorimeter to assess metabolic response to small-calorie loads
Baugh, M. E.; Ahrens, M. L.; Hutelin, Z.; Stylianos, C.; Wohlers-Kariesch, E.; Oster, M. E.; Dotson, J.; Moon, J.; Hanlon, A. L. E.; DiFeliceantonio, A. G.
10.1101/2023.09.21.558672 — physiology — Posted on 2023-09-23
1196 BaRDIC: robust peak calling for RNA-DNA interaction data
Mylarshchikov, D. E.; Nikolskaya, A. I.; Bogomaz, O. D.; Ryabykh, G. K.; Zharikova, A. A.; Mironov, A. A.
10.1101/2023.09.21.558815 — bioinformatics — Posted on 2023-09-23
1199 Massive detection of cryptic recessive genetic defects in cattle mining millions of life histories
Besnard, F.; Guintard, A.; Grohs, C.; Guzylack-Piriou, L.; Cano, M.; Escouflaire, C.; Hoze, C.; Leclerc, H.; Buronfosse, T.; Dutheil, L.; Jourdain, J.; Barbat, A.; Fritz, S.; Deloche, M.-C.; Remot, A.; Gausseres, B.; Clement, A.; Bouchier, M.; Elise, C.; Relun, A.; Plassard, V.; Riviere, J.; Pechoux, C.; Vilotte, M.; Eche, C.; Kuchly, C.; Charles, M.; Boulling, A.; Viard, G.; Minery, S.; Barbey, S.; Birbes, C.; Danchin, C.; Launay, F.; Mattalia, S.; Bonnet, A.; Ravary, B.; Millemann, Y.; Guatteo, R.; Klopp, C.; Gaspin, C.; Iampietro, C.; Donnadieu, C.; Milan, D.; Arcangioli, M.-A.; Boussaha, M
10.1101/2023.09.22.558782 — genetics — Posted on 2023-09-23
1203 Global assessment of effective population sizes: consistent taxonomic differences in meeting the 50/500 rule
Clarke, S. H.; Lawrence, E. R.; Matte, J.-M.; Gallagher, B. K.; Salisbury, S. J.; Michaelides, S. N.; Koumrouyan, R.; Ruzzante, D. E.; Grant, J. W. A.; Fraser, D. J.
10.1101/2023.09.22.558974 — evolutionary biology — Posted on 2023-09-23
1205 Picoeukaryotic photosynthetic potential is functionally redundant but taxonomically structured at global scale
Schickele, A.; Debeljak, P.; Ayata, S.-D.; Bittner, L.; Pelletier, E.; Guidi, L.; Irisson, J.-O.
10.1101/2023.09.22.558943 — ecology — Posted on 2023-09-23
1207 A Genetically Encoded Actuator Selectively Boosts L-type Calcium Channels in Diverse Physiological Settings
del Rivero Morfin, P. J.; Scala Chavez, D.; Jayaraman, S.; Yang, L.; Kochiss, A.; Colecraft, H. M.; Liu, X. S.; Marx, S. O.; Rajadhyaksha, A. M.; Ben-Johny, M.
10.1101/2023.09.22.558856 — physiology — Posted on 2023-09-23
1208 NEUROMETABOLOMIC IMPACTS OF MODELED WILDFIRE SMOKE AND PROTECTIVE BENEFITS OF ANTI-AGING THERAPEUTICS IN AGED FEMALE C57BL/6J MICE
Scieszka, D.; Gu, H.; Barkley-Levenson, A.; Barr, E.; Garcia, M.; Begay, J. G.; Herbert, G.; Bhaskar, K.; McCormick, M.; Brigman, J.; Ottens, A.; Bleske, B.; Campen, M.
10.1101/2023.09.21.558863 — pharmacology and toxicology — Posted on 2023-09-23
1209 Role Of The C-C Motif Chemokine Ligand 5 (CCL5) And Its Receptor, C-C Motif Chemokine Receptor 5 (CCR5) In The Genesis Of Aldosterone-induced Hypertension, Vascular Dysfunction, And End-organ Damage
Costa, R. M.; Cerqueira, D. M.; Bruder do Nascimento, A.; Alves, J. V.; Awata, W. M. C.; Singh, S.; Kufner, A.; Cifuentes-Pagano, E.; Pagano, P. J.; Ho, J.; Bruder-Nascimento, T.
10.1101/2023.09.22.558020 — pharmacology and toxicology — Posted on 2023-09-23
1210 ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
Ohara, Y.; Craig, A. J.; Liu, H.; Yang, S.; Moreno, P.; Dorsey, T. H.; Cawley, H.; Azizian, A.; Gaedcke, J.; Ghadimi, M.; Hanna, N.; Ambs, S.; Hussain, S. P.
10.1101/2023.09.23.558894 — cancer biology — Posted on 2023-09-23
1211 Assessing the link between tissue elasticity and plant growth
Laplaud, V.; Demidova, N.; Muller, E.; Drevensek, S.; Boudaoud, A.
10.1101/2023.09.21.558781 — biophysics — Posted on 2023-09-23
1214 Structural Flexibility and Disassembly Kinetics of Single Ferritins using Optical Nanotweezers
Yousefi, A.; Zheng, Z.; Zargarbashi, S.; Assadipapari, M.; Hickman, G. J.; Parmenter, C. D. J.; Sanderson, G.; Craske, D.; Xu, L.; Rahmani, M.; Ying, C.
10.1101/2023.09.22.558948 — biophysics — Posted on 2023-09-23
1217 An Integrated Comparative Genomics, Subtractive Proteomics and Immunoinformatics Framework for the Rational Design of a Pan-Salmonella Multi-Epitope Vaccine
Bhattacharjee, A.; Hosen, M. R.; Lamisa, A. B.; Ahammad, I.; Chowdhury, Z. M.; Jamal, T. B.; Sohag, M. M. H.; Hossain, M. U.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.09.21.558749 — bioinformatics — Posted on 2023-09-23
1219 starTracer: An Accelerated Approach for Precise Marker Gene Identification in Single-Cell RNA-Seq Analysis
Zhang, F.; Huang, K.; Chen, R.; Zhao, Q.; Liu, Z.; Ma, W.; Hou, S.; Wang, D. O.; Wei, W.; Li, X.
10.1101/2023.09.21.558919 — bioinformatics — Posted on 2023-09-23
1224 Genomic comparison of the temperate coral Astrangia poculata with tropical corals yields insights into winter quiescence, innate immunity, and sexual reproduction
Stankiewicz, K. H.; Guiglielmoni, N.; Kitchen, S. A.; Flot, J.-F.; Barott, K. L.; Davies, S. W.; Finnerty, J. R.; Grace, S. P.; Kaufman, L. S.; Putnam, H. M.; Rotjan, R. D.; Sharp, K. H.; Baums, I. B.
10.1101/2023.09.22.558704 — genomics — Posted on 2023-09-23
1225 Leishmaniinae: evolutionary inferences based on protein expression profiles (PhyloQuant) congruent with phylogenetic relationships among Leishmania, Endotrypanum, Porcisia, Zelonia, Crithidia, and Leptomonas
Mule, S. N.; Aleman, E. V.; Fernandes, L. R.; Saad, J. S.; de Oliveira, G. S.; Martins, D.; Angeli, C. B.; Brandt-Almeida, D.; Cortez, M.; Larsen, M. R.; Shaw, J. J.; Teixeira, M. M. G.; Palmisano, G.
10.1101/2023.09.22.558958 — evolutionary biology — Posted on 2023-09-23
1230 Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability
Patterson, M. T.; Xu, Y.; Hillman, H.; Osinski, V.; Schrank, P. R.; Kennedy, A. E.; Zhu, A.; Tollison, S.; Shekhar, S.; Stromnes, I.; Tassi, I.; Wu, D.; Binstadt, B.; Williams, J. W.
10.1101/2023.09.21.558810 — immunology — Posted on 2023-09-23
1231 Ketone supplementation dampens subjective and objective responses to alcohol in rats and humans
Li, X.; Shi, Z.; Todaro, D.; Pond, T.; Byanyima, J.; Vesslee, S.; Reddy, R.; Nanga, R. N. P. R.; Kass, G.; Ramchandani, V.; Kranzler, H.; Vendruscolo, J.; Vendruscolo, L.; Wiers, C. E.
10.1101/2023.09.23.558269 — pharmacology and toxicology — Posted on 2023-09-23
1232 Mosquitoes do not like bitter: new perspectives for biorational repellents
Lazzari, C. R.; Ortega-Insaurralde, I.; Esnault, J.; Costa, E.; Crespo, J. E.; Barrozo, R. B.
10.1101/2023.09.21.558838 — zoology — Posted on 2023-09-23
1233 KRAS inhibition activates an actionable CD24 do-not-eat-me signal in pancreas cancer
Wei, Y.; Liu, M.; Yen, E.-Y.; Yao, J.; Nguyen, P. T.; Wang, X.; Yang, Z.; Yousef, A.; Pan, D.; Jin, Y.; Theady, M. S.; Park, J.; Cai, Y.; Takeda, M.; Vasquez, M.; Zhou, Y.; Zhao, H.; Viale, A.; Wang, H.; Zhao, D.; DePinho, R. A.; Yao, W.; Ying, H.
10.1101/2023.09.21.558891 — cancer biology — Posted on 2023-09-23
1234 Asymmetric Contribution of a Selectivity Filter Gate in Triggering Inactivation of CaV1.3 Channels
del Rivero Morfin, P. J.; Kochiss, A. L.; Liedl, K. R.; Flucher, B. E.; Fernandez-Quintero, M. L. I.; Ben-Johny, M.
10.1101/2023.09.21.558864 — biophysics — Posted on 2023-09-23
1236 B cells occupy a unique, dynamic, biological niche within the human myocardium
Bermea, K. C.; Duque, C.; Cohen, C. D.; Bhalodia, A.; Rousseau, S.; Lovell, J.; Zita, M. D.; Mugnier, M. C.; Adamo, L.
10.1101/2023.09.21.558902 — immunology — Posted on 2023-09-23
1239 The atypical cadherin FAT1 is a novel regulator of STAT1, driving its pro-tumorigenic effect via the STAT1/PDCD4 axis in glioblastoma
Khan, M. T.; Malik, N.; Jalota, A.; Sharma, S.; Almas, M.; Luthra, K.; Suri, V.; Suri, A.; Seth, P.; Chosdol, K.; Sinha, S.
10.1101/2023.09.22.558772 — cancer biology — Posted on 2023-09-23
1241 MCell4 with BioNetGen: A Monte Carlo Simulator of Rule-Based Reaction-Diffusion Systems with Python Interface
Husar, A.; Ordyan, M.; Garcia, G. C.; Yancey, J. G.; Saglam, A. S.; Faeder, J.; Bartol, T. M.; Kennedy, M. B.; Sejnowski, T. J.
10.1101/2022.05.17.492333 — biophysics — Posted on 2023-09-23
1243 Characterization of RBM15 protein binding with long noncoding RNAs
Bose, E.; Mayes, C.; Ellis, L.; Baker, C.; Tambalotti, S.; Xiong, S.; Sarpong, Y. P. O.; Shalaby, M.; Barry, L.; Lewis, F.; Joseph, J.; Isaacs, T.; McCarthy, D.; Katz, D.; Wang, J.; Zirimu, V.; Vargas, L.; Von Hofe, J.; Aguilar, G.; Buchan, K.; Zheng, L.; Wolfe, G.; Jones, A.
10.1101/2023.07.20.549950 — biochemistry — Posted on 2023-09-23
1245 Phenotypic divergence and genomic architecture at two different stages of speciation in a marine snail
Raffini, F.; De Jode, A.; Johannesson, K.; Faria, R.; Zagrodzka, Z. B.; Westram, A. M.; Galindo, J.; Rolan-Alvarez, E.; Butlin, R. K.
10.1101/2023.09.21.558824 — evolutionary biology — Posted on 2023-09-23
1247 AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML
Sayitoglu, E. C.; Luca, B. A.; Boss, A. P.; Thomas, B. C.; Freeborn, R. A.; Uyeda, M. J.; Chen, P. P.; Nakauchi, Y.; Waichler, C.; Lacayo, N. J.; Bacchetta, R.; Majeti, R.; Gentles, A. J.; Cepika, A.-M.; Roncarolo, M. G.
10.1101/2023.09.21.558911 — immunology — Posted on 2023-09-23
1248 A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis
Singh, J.; Sarkar, B.; Yadav, M.; Deka, A.; Markandey, M.; Sanyal, P.; Nagarajan, P.; Gaikward, N.; Ahuja, V.; Mohanty, D.; Basak, S.; Gokhale, R. S.
10.1101/2023.09.21.558851 — immunology — Posted on 2023-09-23
1249 Simultaneous estimation of gene regulatory network structure and RNA kinetics from single cell gene expression
Jackson, C. A.; Beheler-Amass, M.; Tjärnberg, A.; Suresh, I.; Hickey, A. S.-m.; Bonneau, R.; Gresham, D. J.
10.1101/2023.09.21.558277 — systems biology — Posted on 2023-09-23
1251 S100A8/A9 predicts triple-negative breast cancer response to PIM kinase and PD-1/PD-L1 inhibition
Begg, L. R.; Orriols, A. M.; Zannikou, M.; Yeh, C.; Vadlamani, P.; Kanojia, D.; Bolin, R.; Dunne, S. F.; Balakrishnan, S.; Camarda, R.; Roth, D.; Zielinski-Mozny, N. A.; Yau, C.; Vassilopoulos, A.; Huang, T.-H.; Kim, K.-Y. A.; Horiuchi, D.
10.1101/2023.09.21.558870 — cancer biology — Posted on 2023-09-23
1253 Chitinase 3-like-1 (CHI3L1) in the Pathogenesis of Epidermal Growth Factor Receptor Mutant Non-Small Cell Lung Cancer
Kamle, S.; Ma, B.; Schor, G.; Bailey, M.; Pham, B.; Cho, I.; Khan, H.; Azzoli, C.; Hofstetter, M.; Lee, C.-M.; Herbst, R.; Politi, K.; Lee, C. G.; Elias, J. A.
10.1101/2023.09.21.558861 — cancer biology — Posted on 2023-09-23
1254 PseudoCell: A collaborative network for in silico prediction of regulatory pathways
Pierdona, V.; Lavandoski, P.; Maurmann, R. M.; Borges, G. A.; Mombach, J. C. M.; Guma, F. T. C. R.; Barbe-Tuana, F. M.
10.1101/2023.07.20.549793 — bioinformatics — Posted on 2023-09-23
1255 Reference Sequence Browser: An R application with a User-Friendly GUI to rapidly query sequence databases
Rapp, S. L.; Tapias Gomez, J.; Ramesh, S.; Levine, B.; Tapias-Gomez, D.; Chung, D.; Truong, Z.
10.1101/2023.09.20.558722 — bioinformatics — Posted on 2023-09-23
1258 Gcm alleviates the inflammatory phenotype induced by Toll activation in Drosophila hemocytes
Bazzi, W.; Monticelli, S.; Delaporte, C.; Riet, C.; Giangrande, A.; Cattenoz, P. B.
10.1101/2023.09.21.558811 — immunology — Posted on 2023-09-23
1263 Rebound activation of 5-HT neurons following SSRI discontinuation
Collins, H. M.; Gullino, L. S.; Ozdemir, D.; Lazarenco, C.; Sudarikova, Y.; Daly, E.; Pilar Cuellar, F.; Pinacho, R.; Bannerman, D. M.; Sharp, T.
10.1101/2023.09.23.558888 — neuroscience — Posted on 2023-09-23
1264 Automatic monitoring of whole-body neural activity in behaving Hydra
Hanson, A.; Reme, R.; Telerman, N.; Yamamoto, W.; Olivo-Marin, J.-C.; Lagache, T.; Yuste, R.
10.1101/2023.09.22.559063 — neuroscience — Posted on 2023-09-23
1265 Estimating multimodal brain variability in schizophreniaspectrum disorders: A worldwide ENIGMA study
Omlor, W.; Rabe, F.; Fuchs, S.; Cecere, G.; Homan, S.; Surbeck, W.; Kallen, N.; Georgiadis, F.; Seifritz, E.; Weickert, T.; Bruggemann, J.; Weickert, C.; Potkin, S.; Hashimoto, R.; Sim, K.; Rootes-Murdy, K.; Quide, Y.; Houenou, J.; Banaj, N.; Vecchio, D.; Piras, F.; Spalletta, G.; Salvador, R.; Rodrigue, A.; Pearlson, G.; Glahn, D.; Tomecek, D.; Kirschner, M.; Kochunov, P.; Fan, F.-M.; Andreassen, O.; Westlye, L. T. A.; Berthet, P.; Calhoun, V.; Howells, F. M.; Uhlmann, A.; Stein, D.; Iasevoli, F.; van Erp, T.; Turner, J.; Homan, P.
10.1101/2023.09.22.559032 — neuroscience — Posted on 2023-09-23
1269 Male violence disrupts estrogen receptor β signaling in the female hippocampus
Agrimi, J.; Bernardele, L.; Sbaiti, N.; Canato, M.; Marchionni, I.; Oeing, C. U.; Vignoli, B.; Canossa, M.; Kaludercic, N.; Lodovichi, C.; Dal Maschio, M.; Paolocci, N.
10.1101/2023.09.23.559092 — neuroscience — Posted on 2023-09-23
1270 Oncogenic functions of the m6A demethylase FTO in breast cancer cells involving translational upregulation of C/EBPβ-LIP
Zuidhof, H. R.; Müller, C.; Kortman, G.; Wardenaar, R.; Stepanova, E.; Loayza-Puch, F.; Calkhoven, C. F.
10.1101/2023.09.21.558784 — cancer biology — Posted on 2023-09-23
1274 GammaGateR: semi-automated marker gating for single-cell multiplexed imaging
Xiong, J.; Kaur, H.; Heiser, C. N.; McKinley, E. T.; Roland, J. T.; Coffey, R. J.; Shrubsole, M. J.; Wrobel, J.; Ma, S.; Lau, K. S.; Vandekar, S.
10.1101/2023.09.20.558645 — bioinformatics — Posted on 2023-09-23
1277 Grain Utilization by the Gut Microbiome as a Human Health Phenotype to Identify Multiple Effect Loci in Genome-Wide Association Studies of Sorghum bicolor
Korth, N.; Yang, Q.; Van Haute, M. J.; Tross, M. C.; Peng, B.; Shrestha, N.; Zwiener, M.; Mural, R. V.; Schnable, J. C.; Benson, A. K.
10.1101/2023.09.20.558616 — genomics — Posted on 2023-09-23
1278 Germline-targeting chimpanzee SIV Envelopes induce V2-apex broadly neutralizing-like B cell precursors in a rhesus macaque infection model
Musharrafieh, R.; Safonova, Y.; Song, G.; Roark, R. S.; Lee, F.-H.; Zhang, S.; Hurtado, J.; Yong, P.; Wang, S.; Russell, R. M.; Ding, W.; Li, Y.; Rando, J.; Murphy, A. I.; Lindemuth, E.; Zhao, C.; Connell, A. J.; Lee, W.-H.; Mishra, N.; Avillion, G.; He, W.; Callaghan, S.; Dueker, K.; Vo, A. L.; Li, X.; Capozzola, T.; Joyce, C.; Zhao, F.; Anzanello, F.; Liu, W.; Bibollet-Ruche, F.; Ramos, A.; Li, H.; Lewis, M. G.; Ozorowski, G.; Landais, E.; Foley, B. T.; Wagh, K.; Sok, D.; Briney, B.; Ward, A. B.; Hahn, B. H.; Burton, D. R.; Shaw, G. M.; Andrabi, R.
10.1101/2023.09.21.558743 — immunology — Posted on 2023-09-23
1280 Dynamics of endogenous and water cortisol release in Asian Seabass Lates calcarifer after acute stress in a farm scale recirculating aquaculture system
Tan, M. R.; Aung, K. M. M.; Salleh, N. A. b. M.; Tan, J. Y. A.; Chua, K. X.; Doblado, G. J.; Chua, K. L.; Tham, V.; Lin, J. J.; Chaganty, V.; Yusoff, D. M.; Vij, S.; Su, X.; Sutarlie, L.; Wee, C. L.
10.1101/2023.09.20.558587 — physiology — Posted on 2023-09-23
1283 Reference Sequence Browser: An R application with a User-Friendly GUI to rapidly query sequence databases
Tapias Gomez, J.; Ramesh, S.; Chung, D.; Levine, B.; Truong, Z.; Rapp, S. L.; Tapias-Gomez, D.
10.1101/2023.09.20.558722 — bioinformatics — Posted on 2023-09-23
1288 Patterns and drivers of pollen co-transport networks vary across pollinator groups
Carneiro, L. T.; Williams, J. N.; Barker, D. A.; Anderson, J. W.; Martel, C.; Arceo-Gomez, G.
10.1101/2023.09.20.558666 — ecology — Posted on 2023-09-23
1292 KSHV 3.0: A State-of-the-Art Annotation of the Kaposi's Sarcoma-Associated Herpesvirus Transcriptome Using Cross-Platform Sequencing
Prazsak, I.; Tombacz, D.; Fülöp, A.; Torma, G.; Gulyas, G.; Dörmo, A.; Kakuk, B.; McKenzie Spires, L.; Toth, Z.; Boldogkoi, Z.
10.1101/2023.09.21.558842 — microbiology — Posted on 2023-09-23
1293 Geranylgeranyl pyrophosphate (GGPP) is associated with hepatic lipid accumulation and insulin resistance in MAO by prenylating Perilipin4
Li, C.; Zhao, Y.; Jiang, S.; Nie, H.-Y.; Zhao, M.-F.; Sun, P.; Zhang, J.-Z.; Wang, X.-C.; Tang, Y.-P.; Yuan, X.-W.; Sun, X.-T.; Shan, X.-D.; He, J.; Liu, J.-H.; Bi, Y.; Fang, L.; Han, X.
10.1101/2023.09.19.558458 — pathology — Posted on 2023-09-23
1294 Acidic nanoparticles restore lysosomal acidification and rescue metabolic dysfunction in pancreatic β-cells under lipotoxic condition
Lo, C. H.; O'Connor, L. M.; Loi, G. W. Z.; Saipuljumri, E. N.; Indajang, J.; Lopes, K. M.; Shirihai, O. S.; Grinstaff, M. W.; Zeng, J.
10.1101/2023.07.11.548395 — bioengineering — Posted on 2023-09-23
1296 Females translate male mRNA transferred during mating
Matzkin, L. M.; Bono, J. M.; Pigage, H.; Allan, C. W.; Diaz, F.; McCoy, J.; Green, C.; Callan, J.; Delahunt, S.
10.1101/2023.09.22.558997 — evolutionary biology — Posted on 2023-09-23
1297 Single-cell DNA replication dynamics in genomically unstable cancers
Weiner, A. C.; Williams, M. J.; Shi, H.; Vazquez-Garcia, I.; Salehi, S.; Rusk, N.; Aparicio, S.; Shah, S. P.; McPherson, A.
10.1101/2023.04.10.536250 — cancer biology — Posted on 2023-09-23
1298 De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression
Tangudu, N. K.; Buj, R.; Wang, H.; Wang, J.; Cole, A. R.; Uboveja, A.; Fang, R.; Amalric, A.; Sajjakulnukit, P.; Lyons, M. A.; Cooper, K.; Hempel, N. W.; Snyder, N. W.; Lyssiotis, C. A.; Chandran, U. R.; Aird, K. M.
10.1101/2023.07.15.549149 — cancer biology — Posted on 2023-09-23
1300 Microbial strong organic ligand production is tightly coupled to iron in hydrothermal plumes
Hoffman, C. L.; Monreal, P. J.; Albers, J. B.; Lough, A. J. M.; Santoro, A. E.; Mellett, T.; Buck, K. N.; Tagliabue, A.; Lohan, M. C.; Resing, J. A.; Bundy, R. M.
10.1101/2023.01.05.522639 — biochemistry — Posted on 2023-09-23
1304 Metabolic plasticity of serine metabolism is crucial for cGAS/STING-signalling and innate immune response to viral infections in the gut
Becker, B.; Wottawa, F.; Bakr, M.; Koncina, E.; Mayr, L.; Kugler, J.; Yang, G.; Windross, S. J.; Neises, L.; Mishra, N.; Harris, D.; Tran, F.; Welz, L.; Schwaerzler, J.; Banki, Z.; Stengel, S. T.; Ito, G.; Kroetz, C.; Coleman, O.; Jaeger, C.; Haller, D.; Paludan, S. R.; Blumberg, R.; Kaser, A.; Cicin-Sain, L.; Schreiber, S.; Letellier, E.; Adolph, T.; Rosenstiel, P.; Meiser, J.; Aden, K.
10.1101/2022.05.17.492340 — cell biology — Posted on 2023-09-23
1306 Exoribonuclease RNase R protects Antarctic Pseudomonas syringae Lz4W from DNA damage and oxidative stress
Mittal, P.; Sipani, R.; Pandiyan, A.; Sulthana, S.; Sinha, A. K.; Hussain, A.; Ray, M. K.; Pavankumar, T. L.
10.1101/2023.06.01.543265 — microbiology — Posted on 2023-09-23
1308 Heligmosomoides bakeri and Toxoplasma gondii co-infection leads to increased mortality associated with intestinal pathology
Szabo, E. K.; Bowhay, C.; Forrester, E.; Liu, H.; Dong, B.; Coria, A. L.; Perera, S.; Fung, B.; Badawadagi, N.; Gaio, C.; Bailey, K.; Ritz, M.; Bowron, J.; Ariyaratne, A.; Finney, C. A. M.
10.1101/2021.05.27.445631 — immunology — Posted on 2023-09-23
1309 Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease
Colom-Cadena, M.; Toombs, J.; Simzer, E.; Tulloch, J.; Jackson, R. J.; Catterson, J. H.; Rose, J.; Waybright, L.; Caggiano, A.; Davies, C.; Hooley, M.; Dunnett, S.; Tempelaar, R.; Tzioras, M.; Hamby, M. E.; Izzo, N. J.; Catalano, S. M.; Smith, C.; Dando, O. R.; Spires-Jones, T. L.
10.1101/2021.02.01.428238 — neuroscience — Posted on 2023-09-23
1310 CelltypeR: A flow cytometry pipeline to annotate, characterize and isolate single cells from brain organoids
Thomas, R. A.; Sirois, J.; Li, S.; Gestin, A.; Deyab, G. E.; Piscopo, V. E.; Lepine, P.; Mathur, M.; Chen, C. X. Q.; Soubannier, V.; Goldsmith, T. M.; Fawaz, L.; Durcan, T. M.; Fon, E. A.
10.1101/2022.11.11.516066 — neuroscience — Posted on 2023-09-23
1311 Maintenance and transformation of representational formats during working memory prioritization
Estefan, D. P.; Fellner, M. C.; Kunz, L.; Zhang, H.; Reinacher, P.; Roy, C.; Brandt, A.; Schulze-Bonhage, A.; Yang, L.; Wang, S.; Liu, J.; Xue, G.; Axmacher, N.
10.1101/2023.02.08.527513 — neuroscience — Posted on 2023-09-23
1312 NeuroMechFly 2.0, a framework for simulating embodied sensorimotor control in adult Drosophila
Wang-Chen, S.; Stimpfling, V. A.; Ozdil, P. G.; Genoud, L.; Hurtak, F.; Ramdya, P.
10.1101/2023.09.18.556649 — neuroscience — Posted on 2023-09-23
1314 Generalizing Stepping Concepts To Non-Straight Walking
Dingwell, J. B.; Render, A. C.; Desmet, D. M.; Cusumano, J. P.
10.1101/2023.05.15.540644 — neuroscience — Posted on 2023-09-23
1317 Signal recovery in single cell batch integration
Zhang, Z.; Mathew, D.; Lim, T.; Mason, K.; Martinez, C. M.; Huang, S.; Wherry, E. J.; Susztak, K.; Minn, A. J.; Ma, Z.; Zhang, N. R.
10.1101/2023.05.05.539614 — bioinformatics — Posted on 2023-09-23
1322 Microfibril-associated glycoprotein 4 forms octamers that mediate interactions with elastogenic proteins and cells
Wozny, M. R.; Nelea, V.; Siddiqui, I. F. S.; Wanga, S.; de Waard, V.; Strauss, M.; Reinhardt, D. P.
10.1101/2023.09.22.558839 — cell biology — Posted on 2023-09-22
1323 Characterization and optimization of variability in a human colonic epithelium culture model
Pike, C. M.; Zwarycz, B.; McQueen, B. E.; Castillo, M.; Barron, C.; Morowitz, J. M.; Levi, J. A.; Phadke, D.; Balik-Meisner, M.; Mav, D.; Shah, R.; Cunningham Glasspoole, D. L.; Laetham, R.; Thelin, W.; Bunger, M. K.; Boazak, E. M.
10.1101/2023.09.22.559007 — cell biology — Posted on 2023-09-22
1324 Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids
Yang, X.; Forro, C.; Li, T. L.; Miura, Y.; Zaluska, T.; Tsai, C.-T.; Kanton, S.; McQueen, J. P.; Chen, X.; Mollo, V.; Santoro, F.; Pasca, S. P.; Cui, B.
10.1101/2023.09.22.559050 — neuroscience — Posted on 2023-09-22
1325 Sortilin inhibition treats multiple neurodegenerative lysosomal storage disorders.
Leppert, H. G.; Anderson, J. T.; Timm, K. J.; Davoli, C.; Pratt, M. A.; Booth, C. D.; White, K. A.; Rechtzigel, M.; Meyerink, B. L.; Johnson, T. B.; Brudvig, J. B.; Weimer, J. M.
10.1101/2023.09.22.559064 — neuroscience — Posted on 2023-09-22
1327 Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism
Perez, Y.; Velmeshev, D.; Wang, L.; White, M.; Siebert, C.; Baltazar, J.; Dutton, N. G.; Wang, S.; Haeussler, M.; Chamberlain, S.; Kriegstein, A.
10.1101/2023.09.22.559056 — neuroscience — Posted on 2023-09-22
1328 Inhibition of mammalian mtDNA transcription paradoxically activates liver fatty acid oxidation to reverse diet-induced hepatosteatosis and obesity
Jiang, S.; Yuan, T.; Kremer, L. S.; Rosenberger, F. A.; Hansen, F. M.; Borg, M.; Rubalcava-Gracia, D.; Mennuni, M.; Filograna, R.; Alsina, D.; Misic, J.; Koolmeister, C.; Ren, L.; Andersson, O.; Unger, A.; Bergbrede, T.; Lucrezia, R. D.; Wilbom, R.; Zierath, J. R.; Krook, A.; Giavalisco, P.; Mann, M.; Larsson, N.-G.
10.1101/2023.09.22.558955 — physiology — Posted on 2023-09-22
1330 Neural stem cells protect the integrity of blood-brain barrier via the p38, JNK and ERK1/2 pathways following intracerebral hemorrhage in rats
Sun, J.; yang, x.; Kim, T. J.; Kim, Y.-J.; Wei, Z.; Han, L.; Carmichael, A.; Stanciu, N.; Ko, S.-B.; Nan, G.; Yoon, B.-W.
10.1101/2023.09.22.558889 — neuroscience — Posted on 2023-09-22
1331 The Silene latifolia genome and its giant Y chromosome
Moraga, C.; Branco, C.; Rougemont, Q.; Veltsos, P.; Jedlicka, P.; Muyle, A.; Hanique, M.; Tannier, E.; Liu, X.; Mendoza-Galindo, E.; Lemaitre, C.; Fields, P. D.; Cruaud, C.; Labadie, K.; Belser, C.; Briolay, J.; Santoni, S.; Cegan, R.; Linheiro, R.; Rodriguez de la Vega, R.; Adam, G.; El Filali, A.; Mossion, V.; Boualem, A.; Tavares, R.; Chebbi, A.; Cordaux, R.; Fruchard, C.; Prentout, D.; Velt, A.; Spataro, B.; Delmotte, S.; Weingartner, L.; Toegelova, H.; Tulpova, Z.; Capal, P.; Simkova, H.; Storchova, H.; Kruger, M.; Abeyawardana, O. A.; Taylor, D.; Olson, M.; Sloan, D. B.; Karrenberg, S.;
10.1101/2023.09.21.558754 — genomics — Posted on 2023-09-22
1332 Alterations of metagenomics and metaproteomics associate kidney disease in a combination of opisthorchiasis and nonalcoholic fatty liver disease
Tunbenjasiri, K.; Pongking, T.; Sitthirach, C.; Kongsintaweesuk, S.; Roytrakul, S.; Charoenlappanit, S.; Klungsaeng, S.; Anutrakulchai, S.; Chalermwat, C.; Pinlaor, S.; Pinlaor, P.
10.1101/2023.09.20.558740 — bioinformatics — Posted on 2023-09-22
1336 Diet composition drives tissue-specific intensity of murine enteric infections
Israelsen, H.; Vedsted-Jakobsen, A.; Zhu, L.; Gagnaire, A.; von Munchow, A.; Polakovicova, N.; Valente, A.; Raza, A.; Andersen-Civil, A.; Olsen, J. E.; Myhill, L.; Geldhof, P.; Williams, A.
10.1101/2023.09.22.558956 — microbiology — Posted on 2023-09-22
1341 eQTLs identify regulatory networks and drivers of variation in the individual response to sepsis
Burnham, K. L.; Milind, N.; Lee, W.; Kwok, A. J.; Cano-Gamez, E.; Mi, Y.; Geoghegan, C. G.; GAinS Investigators, ; McKechnie, S.; Soranzo, N.; Hinds, C. J.; Knight, J. C.; Davenport, E. E.
10.1101/2023.09.22.558983 — genomics — Posted on 2023-09-22
1345 Mosquito aging modulates the development, virulence and transmission potential of pathogens
Some, B.; Guissou, E.; Da, D.; Richard, Q.; Choisy, M.; Yameogo, K.; Hien, D. F. d. S.; Yerbanga, R. S.; Ouedraogo, G. A.; Dabire, K. R.; Djidjou-Demasse, R.; Cohuet, A.; Lefevre, T.
10.1101/2023.09.21.558787 — ecology — Posted on 2023-09-22
1347 Impaired bone morphogenetic protein signaling pathways disrupt decidualization in endometriosis
Liao, Z.; Tang, S.; Jiang, P.; Geng, T.; Cope, D. I.; Dunn, T. N.; Guner, J.; Alpuing Radilla, L.; Guan, X.; Monsivais, D.
10.1101/2023.09.21.558268 — molecular biology — Posted on 2023-09-22
1349 Spinal cord pathology in a Dravet Syndrome mouse model
Antinao Diaz, J. F.; Chilcott, E.; Keegan, A.; Schorge, S.; Waddington, S. N.; Karda, R.
10.1101/2023.09.22.558962 — molecular biology — Posted on 2023-09-22
1350 Transmission dynamics and pathogenesis differ between pheasants and partridges infected with clade 2.3.4.4b H5N8 and H5N1 high-pathogenicity avian influenza viruses
Seekings, A. H.; Liang, Y.; Warren, C. J.; Hjulsager, C. K.; Thomas, S. S.; Lean, F. Z.; Nunez, A.; Skinner, P.; Selden, D.; Falchieri, M.; Simmons, H.; Brown, I. H.; Larsen, L. E.; Banyard, A. C.; Slomka, M. J.
10.1101/2023.09.22.558959 — microbiology — Posted on 2023-09-22
1356 Target-based discovery of a broad spectrum flukicide
Sprague, D. J.; Park, S.-K.; Gramberg, S.; Bauer, L.; Rohr, C. M.; Chulkov, E. G.; Smith, E.; Scampavia, L.; Spicer, T. P.; Haeberlein, S.; Marchant, J.
10.1101/2023.09.22.559026 — microbiology — Posted on 2023-09-22
1357 Targeted hypermutation of putative antigen sensors in multicellular bacteria
Dore, H.; Eisenberg, A. R.; Junkins, E. N.; Ganesh, A.; Cordero, O. X.; Paul, B. G.; Valentine, D. L.; O'Malley, M. A.; Wilbanks, E. G.
10.1101/2023.09.22.558884 — microbiology — Posted on 2023-09-22
1358 A phage nucleus-associated RNA-binding protein is required for jumbo phage infection
Enustun, E.; Armbruster, E. G.; Lee, J.; Zhang, S.; Yee, B. A.; Gu, Y.; Deep, A.; Naritomi, J. T.; Liang, Q.; Aigner, S.; Adler, B. A.; Cress, B. F.; Doudna, J. A.; Chaikeeratisak, V.; Cleveland, D. W.; Ghassemian, M.; Yeo, G. W.; Pogliano, J.; Corbett, K. D.
10.1101/2023.09.22.559000 — microbiology — Posted on 2023-09-22
1360 Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection
Gewirtz, A. T.; Ngo, V.; Lieber, C.; Plemper, R. K.; Sakomoto, K.; Kuczma, M. P.; Kang, H.-j.
10.1101/2023.09.21.558814 — immunology — Posted on 2023-09-22
1361 Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation.
Cosson, C.; Riou, R.; Patoli, D.; Niu, T.; Rey, A.; Groslambert, M.; Chatre, E.; Allatif, O.; Henry, T.; Venet, F.; Milhavet, F.; Boursier, G.; Belot, A.; Jamilloux, Y.; Merlin, E.; Duquesne, A.; Grateau, G.; Savey, L.; Maria, A. T. J.; Pagnier, A.; Poutrel, S.; Lambotte, O.; Mallebranche, C.; Rieux-Laucat, F.; Bader-Meunier, B.; Amoura, Z.; Melki, I.; Touitou, I.; Geyer, M.; Georgin-Lavialle, S.; Py, B. F.
10.1101/2023.09.22.558949 — immunology — Posted on 2023-09-22
1363 Autophagy contributes to homeostasis in esophageal epithelium where high autophagic vesicle content marks basal cells with limited proliferation and enhanced self-renewal potential
Klochkova, A.; Karami, A. L.; Fuller, A. D.; Parham, L. R.; Panchani, S. R.; Natarajan, S.; Jackson, J. L.; Mu, A.; Tan, Y.; Cai, K. Q.; Klein-Szanto, A.; Muir, A. B.; Tetreault, M.-P.; Hamilton, K. E.; Whelan, K. A.
10.1101/2023.09.20.558614 — physiology — Posted on 2023-09-22
1364 Structural basis of transcription: RNA Polymerase II substrate binding and metal coordination at 3.0 A using a free-electron laser
Guowu, L.; Barnes, C. O.; Weiss, S.; Dutagaci, B.; Qiu, C.; Feig, M.; Lyubimov, A.; Song, J.; Cohen, A. E.; Kaplan, C. D.; Calero, G.
10.1101/2023.09.22.559052 — biophysics — Posted on 2023-09-22
1368 CD8 T cell hyperfunction and reduced tumour control in models of advanced liver fibrosis
Madani, J.; Li, J.; Vranjkovic, A.; Jorritsma, K.; Hasim, M. S.; Daneshmand, M.; Cheung, A. C.; Ching, A. M. E.; Bruin, J. E.; Ardolino, M.; Crawley, A. M.
10.1101/2023.09.20.557752 — immunology — Posted on 2023-09-22
1371 Uncoupling of synaptic loss from amyloid burden by an Alzheimer's disease protective variant of PLCγ2.
Bevan, R.; Maguire, E.; Phillips, T.; Simonazzi, E.; Vassileva, M.; Williams, J.; Taylor, P.
10.1101/2023.09.22.558987 — neuroscience — Posted on 2023-09-22
1372 Exploring an EM-algorithm for banded regression in computational neuroscience
Fuglsang, S. A.; Madsen, K. H.; Puonti, O.; Siebner, H. R.; Hjortkjaer, J.
10.1101/2023.09.22.558945 — neuroscience — Posted on 2023-09-22
1376 Tumor sialylation is a barrier against CD8 T cell-mediated anti-tumor responses and anti-PD-1 resistance in breast cancer
Mereiter, S.; Jonsson, G.; Oliveira, T.; Helm, J.; Hoffmann, D.; Abeln, M.; Jochum, A.-K.; Jochum, W.; Kellner, M. J.; Feith, M.; Tkalec, V.; Wasilewska, K.; Jiao, J.; Emsenhuber, L.; Holstein, F.; Obenauf, A.; Lordello, L.; Scoazec, J.-Y.; Kroemer, G.; Zitvogel, L.; Ali, O. H.; Flatz, L.; Gerardy-Schahn, R.; Muenster-Kuehnel, A.; Stadlmann, J.; Penninger, J. M.
10.1101/2023.09.20.558571 — cancer biology — Posted on 2023-09-22
1381 Sensory experience steers representational drift in mouse visual cortex
Bauer, J.; Lewin, U.; Herbert, E.; Gjorgjieva, J.; Schoonover, C. E.; Fink, A. J. P.; Rose, T.; Bonhoeffer, T.; Hübener, M.
10.1101/2023.09.22.558966 — neuroscience — Posted on 2023-09-22
1382 Single intravitreal administration of a tetravalent siRNA exhibits robust and efficient gene silencing in rodent and swine photoreceptors
Cheng, S.-Y.; Caiazzi, J.; Biscans, A.; Alterman, J. F.; Echeverria, D.; McHugh, N.; Hassler, M.; Jolly, S.; Giguere, D.; Cipi, J.; Khvorova, A.; Punzo, C.
10.1101/2023.09.20.558641 — neuroscience — Posted on 2023-09-22
1383 Neuroimaging and plasma marker evidence for white matter macrostructure loss in Parkinsons disease
Zarkali, A.; Hannaway, N.; McColgan, P.; Heslegrave, A. J.; Veleva, E.; Laban, R.; Zetterberg, H.; Lees, A. J.; Fox, N. C.; Weil, R. S.
10.1101/2023.09.22.558937 — neuroscience — Posted on 2023-09-22
1384 Evaluating functional brain organization in individuals and identifying contributions to network overlap
Bijsterbosch, J. D.; Farahibozorg, S.-R.; Glasser, M. F.; Van Essen, D. C.; Snyder, L.; Woolrich, M. W.; Smith, S. M.
10.1101/2023.09.21.558809 — neuroscience — Posted on 2023-09-22
1385 Division of labor among H3K4 Methyltransferases Defines Distinct Facets of Homeostatic Plasticity
Tsukahara, T.; Kethireddy, S.; Bonefas, K.; Chen, A.; Sutton, B. L.; Dou, Y.; Iwase, S.; Sutton, M. A.
10.1101/2023.09.20.558734 — neuroscience — Posted on 2023-09-22
1389 Periodic and aperiodic changes to cortical EEG in response to pharmacological manipulation
Salvatore, S. V.; Lambert, P. M.; Benz, A.; Rensing, N. R.; Wong, M.; Zorumski, C. F.; Mennerick, S.
10.1101/2023.09.21.558828 — neuroscience — Posted on 2023-09-22
1391 Cryo-EM structure of Alzheimer disease tau filaments with PET ligand MK-6240
Kunach, P.; Vaquer-Alicea, J.; Smith, M. S.; Hopewell, R.; Monistrol, J.; Moquin, L.; Therriault, J.; Tissot, C.; Rahmouni, N.; Massarweh, G.; Soucy, J.-P.; Guiot, M.-C.; Shoichet, B. K.; Rosa-Neto, P. K.; Diamond, M. I.; Shahmoradian, S. H.
10.1101/2023.09.22.558671 — neuroscience — Posted on 2023-09-22
1392 Personality heterophily and friendship as drivers for successful cooperation
Bhattacharjee, D.; Waasdorp, S.; Middelburg, E.; Sterck, E. H. M.; Massen, J. J. M.
10.1101/2023.09.19.558534 — zoology — Posted on 2023-09-22
1395 An accurate probabilistic step finder for time-series analysis
Rojewski, A.; Schweiger, M.; Sgouralis, I.; Comstock, M.; Presse, S.
10.1101/2023.09.19.558535 — biophysics — Posted on 2023-09-22
1397 InSituCor: a toolkit for discovering non-trivial spatial correlations in spatial transcriptomics
Danaher, P.; McGuire, D.; Patrick, M.; Kroeppler, D.; Zhai, H.; Schmid, J.; Beechem, J. M.
10.1101/2023.09.19.558514 — bioinformatics — Posted on 2023-09-22
1398 A multivariate outcome test of covariance
Boetto, C.; Frouin, A.; Henches, L.; Auvergne, A.; Suzuki, Y.; Patin, E.; Bredon, M.; Chiu, A. M.; Milieu Interieur Consortium, ; Sankararaman, S.; Zaitlen, N.; Kennedy, S.; Quintana-Murci, L.; Duffy, D.; Sokol, H.; Aschard, H.
10.1101/2023.09.20.558234 — bioinformatics — Posted on 2023-09-22
1402 Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
Zwick, R. K.; Kasparek, P.; Palikuqi, B.; Viragova, S.; Weichselbaum, L.; McGinnis, C. S.; McKinley, K. L.; Rathnayake, A.; Vaka, D.; Nguyen, V.; Trentesaux, C.; Reyes, E.; Gupta, A.; Gartner, Z. J.; Locksley, R. M.; Gardner, J. M.; Itzkovitz, S.; Boffelli, D.; Klein, O. D.
10.1101/2023.09.20.558726 — genomics — Posted on 2023-09-22
1404 Reversing the escape from herbivory: Knockout of cardiac glycoside biosynthesis in wormseed wallflower (Erysimum cheiranthoides L., Brassicaceae)
Younkin, G. C.; Alani, M. L.; Paez Capador, A.; Fischer, H. D.; Mirzaei, M.; Hastings, A. P.; Agrawal, A.; Jander, G.
10.1101/2023.09.19.558517 — ecology — Posted on 2023-09-22
1408 The glucocorticoid dexamethasone inhibits HIF-1alpha stabilisation and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages.
Clayton, S. A.; Lockwood, C.; O'Neil, J. D.; Daley, K. K.; Hain, S.; Abdelmottaleb, D.; Bolimowska, O. O.; Tennant, D. A.; Clark, A. R.
10.1101/2023.09.20.558626 — immunology — Posted on 2023-09-22
1410 Neural shape mediation analysis
Brochard, J.; Combrisson, E.; Chatard, B.; Lachaux, J.-P.; Brovelli, A.; Daunizeau, J.
10.1101/2023.09.21.558808 — neuroscience — Posted on 2023-09-22
1411 DJ-1 products glycolic acid and D-lactate restore deficient axonal trafficking and DNA damage response in FUS and SOD1-associated amyotrophic lateral sclerosis
Pal, A.; Grossmann, D.; Glass, H.; Zimyanin, V.; Guenther, R.; Catinozzi, M.; Boeckers, T. M.; Sterneckert, J.; Storkebaum, E.; Petri, S.; Wegner, F.; Grill, S.; Pan-Montojo, F.; Hermann, A.
10.1101/2023.09.20.558653 — neuroscience — Posted on 2023-09-22
1412 Microfluidic interfaces for chronic bidirectional access to the brain.
Marcigaglia, S.; De Plus, R.; Vandendriessche, C.; Cuypers, M.-L.; Cools, J.; Hoffman, L.; Vandenbroucke, R.; Dewilde, M.; Haesler, S.
10.1101/2023.09.22.558790 — neuroscience — Posted on 2023-09-22
1418 A Complex Containing the Na+/K+ ATPase Regulates Epileptogenesis in Drosophilamelanogaster
Bermudez, S.; Dean, D. M.; Alkin, V.; Wang, Z.; Pham, H.; Kondo, E.; Amini, A.; Deitcher, D. L.
10.1101/2023.09.22.559031 — neuroscience — Posted on 2023-09-22
1423 Neuroinflammation induces nerve growth factor dependent nociceptor sensitisation in a neonatal rodent model of platinum-based chemotherapy induced neuropathic pain
Da Vitoria Lobo, M.; Hardowar, L.; Valentine, T.; Tomblin, L.; Guest, C.; Sharma, D.; Elphick-Ross, J.; Paul-Clark, M.; Hulse, R. P.
10.1101/2023.09.21.558866 — neuroscience — Posted on 2023-09-22
1425 Multiscale effective connectivity analysis of brain activity using neural ordinary differential equations
Chang, Y.-J.; Chen, Y.-I.; Stealey, H. M.; Zhao, Y.; Lu, H.-Y.; Contreras-Hernandez, E.; Baker, M. N.; Yeh, H.-C.; Santacruz, S. R.
10.1101/2023.09.21.558923 — neuroscience — Posted on 2023-09-22
1427 Mitochondrial complex I deficiency stratifies idiopathic Parkinson's disease
Flones, I.; Toker, L.; Sandnes, D. A.; Castelli, M.; Mostafavi, S.; Lura, N.; Shadad, O.; Fernandez-Vizarra, E.; Painous, C.; Perez-Soriano, A.; Compta, Y.; Molina-Porcel, L.; Alves, G.; Tysnes, O.-B.; Dolle, C.; Nido, G. S.; Tzoulis, C.
10.1101/2023.09.22.558615 — neuroscience — Posted on 2023-09-22
1428 The precision of signals encoding active self-movement
Haynes, J. D.; Gallagher, M.; Culling, J. F.; Freeman, T. C. A.
10.1101/2023.09.20.558633 — neuroscience — Posted on 2023-09-22
1430 Regeneration of actin filament branches from the same Arp2/3 complex
Ghasemi, F.; Cao, L.; Mladenov, M.; Guichard, B.; Way, M.; Jegou, A.; Romet-Lemonne, G.
10.1101/2023.09.22.558980 — biophysics — Posted on 2023-09-22
1438 Natural selection drives emergent genetic homogeneity in a century-scale experiment with barley
Landis, J. B.; Guercio, A. M.; Brown, K. E.; Fiscus, C. J.; Morrell, P. L.; Koenig, D.
10.1101/2023.09.22.557807 — genetics — Posted on 2023-09-22
1442 Hybrid Mimulus flowers attract a new pollinator
Peng, F.; Sun, X.; van Vloten, C.; Correll, J.; Langdon, M.; Ngochanthra, W.; Johnson, K.; Kane, S. A.
10.1101/2023.09.19.558487 — ecology — Posted on 2023-09-22
1445 TMPRSS2 activation of Omicron lineage Spike glycoproteins is regulated by TMPRSS2 cleavage of ACE2
Aggarwal, A.; Fichter, C.; Milogiannakis, V.; Akerman, A.; Ison, T.; Ruiz Silva, M.; Esneau, C.; Bartlett, N.; Burrell, L.; Patel, S.; Churchill, M.; Angelovich, T.; Parry, R.; Sng, J. D.; Neely, G. G.; Moreno, C. L.; Loo, L.; Kelleher, A. D.; Brilot, F.; Khromykh, A.; Turville, S. G.
10.1101/2023.09.22.558930 — microbiology — Posted on 2023-09-22
1446 Developmental effect of RASopathy mutations on neuronal network activity on a chip
Weiss, E.-M.; Guhathakurta, D.; Petruskova, A.; Hundrup, V.; Zenker, M.; Fejtova, A.
10.1101/2023.09.20.558464 — neuroscience — Posted on 2023-09-22
1449 Phase-Precession-Like Effects in the Anterior Insula Cortex during Reward Expectancy
Yang, L.; Lehongre, K.; Ye, H.; Navarro, V.; Lin, Z.; Cheng, S.; Axmacher, N.; Wang, S.; Zhang, H.
10.1101/2023.09.19.558205 — neuroscience — Posted on 2023-09-22
1450 Olfactory learning modulates a neural circuit mediating innate odor-guided behavior in Drosophila
Campetella, F.; Huber, R.; Klappenbach, M.; Wernecke, C.; Locatelli, F.; Felsenberg, J.; Hansson, B. S.; Knaden, M.; Sachse, S.
10.1101/2023.09.20.558596 — neuroscience — Posted on 2023-09-22
1451 Circulating Platelets Modulate Oligodendrocyte Progenitor Cell Differentiation During Remyelination
Philp, A. R.; Reyes, C. R.; Mansilla, J.; Sharma, A.; Zhao, C.; Valenzuela-Krugmann, C.; Rawji, K. S.; Martinez, G. A. G.; Dimas, P.; Hinrichsen, B.; Ulloa-Leal, C.; Waller, A. K.; Bessa de Sousa, D. M.; Castro, M. A.; Aigner, L.; Ehrenfeld, P.; Silva, M. E.; Kazanis, I.; Ghevaert, C.; Franklin, R. J. M.; Rivera, F. J.
10.1101/2023.09.20.558582 — neuroscience — Posted on 2023-09-22
1452 Longitudinal Deep Multi-Omics Profiling in a CLN3Δex7/8 Minipig Model Reveals Novel Biomarker Signatures for Batten Disease
Rechtzigel, M. J.; Lee, B.; Neville, C.; Huang, T.; Campos, A. R.; Motamedchaboki, K.; Hornburg, D.; Johnson, T. B.; Swier, V. J.; Weimer, J. M.; Brudvig, J. J.
10.1101/2023.09.20.558629 — neuroscience — Posted on 2023-09-22
1454 Test-retest reliability of spectral parameterization by 1/f characterization using SpecParam
McKeown, D. J.; Finley, A.; Kelley, N.; Cavanagh, J.; Keage, H.; Baumann, O.; Schinazi, V.; Moustafa, A.; Angus, D.
10.1101/2023.09.20.558566 — neuroscience — Posted on 2023-09-22
1455 Regulatory Mechanisms Orchestrating Cellular Diversity in Cd36+ Olfactory Sensory Neurons Revealed by Single-Cell Multi-omics Analysis.
Jiawen, Y.; Peiyu, S.; Yiheng, L.; Yachao, Z.; Tao, X.; Ziyang, A.; Dongjie, P.; Weixing, Z.; Yicong, X.; Zhongjie, T.; Anan, L.; Jin, X.
10.1101/2023.09.21.558403 — neuroscience — Posted on 2023-09-22
1459 Non-invasive assessment of stimulation-specific changes in cerebral glucose metabolism with functional PET
Godbersen, G. M.; Falb, P.; Klug, S.; Silberbauer, L.; Reed, M. B.; Nics, L.; Hacker, M.; Lanzenberger, R.; Hahn, A.
10.1101/2023.09.20.558617 — neuroscience — Posted on 2023-09-22
1460 A neural signature for the subjective experience of threat anticipation under uncertainty
Liu, X.; Jiao, G.; Zhou, F.; Kendrick, K. M.; Yao, D.; Xiang, S.; Jia, T.; Zhang, X.-Y.; Zhang, J.; Feng, J.; Becker, B.
10.1101/2023.09.20.558716 — neuroscience — Posted on 2023-09-22
1466 Exploring Neural Dynamics in Self-Voice Processing and Perception: Implications for Hallucination Proneness.
Duggirala, S. X.; Honcamp, H.; Schwartze, M.; Amelsvoort, T.; Pinheiro, A.; Linden, D.; Kotz, S. A.
10.1101/2023.09.21.558843 — neuroscience — Posted on 2023-09-22
1469 Bypassing spike sorting: Density-based decoding using spike localization from dense multielectrode probes
Zhang, Y.; He, T.; Boussard, J.; Windolf, C.; Winter, O.; Trautmann, E.; Roth, N.; Barrell, H.; Churchland, M. M.; Steinmetz, N. A.; The International Brain Laboratory, ; Varol, E.; Hurwitz, C.; Paninski, L.
10.1101/2023.09.21.558869 — neuroscience — Posted on 2023-09-22
1470 BK channel gain-of-function disrupts limb control by suppressing neurotransmission during a critical developmental window
Lowe, S. A.; Wilson, A. D.; Aughey, G.; Banarjee, A.; Goble, T.; Simon-Batsford, N.; Sanderson, A.; Kratschmer, P.; Balogun, M.; Gao, H.; Aw, S. S.; Jepson, J. E. C.
10.1101/2023.09.20.558625 — neuroscience — Posted on 2023-09-22
1471 Preconfigured cortico-thalamic neural dynamics constrain movement-associated thalamic activity
Gonzalez-Pereyra, P.; Martinez-Montalvo, M. G.; Ortega-Romero, D. I.; Perez-Diaz, C. I.; Merchant, H.; Tellez, L. A.; Rueda-Orozco, P. E.
10.1101/2023.09.20.558667 — neuroscience — Posted on 2023-09-22
1472 Long-read transcript sequencing identifies differential isoform expression in the entorhinal cortex in a transgenic model of tau pathology
Leung, S. K.; Jeffries, A. R.; Castanho, I.; Bamford, R. A.; Moore, K.; Dempster, E. L.; Brown, J. T.; Ahmed, Z.; O'Neill, P.; Hannon, E.; Mill, J.
10.1101/2023.09.20.558220 — neuroscience — Posted on 2023-09-22
1475 Epileptic responses in marmosets induced by knockdown of CREB Regulated Transcription Coactivator 1 (CRTC1)
Yamamori, T.; Nakagami, Y.; Komatsu, M.; Nakae, K.; Ohtsuka, M.; Hata, J.; Mizukami, H.; Takemori, H.; Ishii, S.; Okano, H.; Watakabe, A.
10.1101/2023.09.22.558929 — neuroscience — Posted on 2023-09-22
1476 The PI3K-AKT-mTOR axis persists as a therapeutic dependency in KRASG12D-driven non-small cell lung cancer
McDaid, W. J.; Wilson, L.; Adderley, H.; Baker, M. J.; Searle, J.; Ginn, L.; Budden, T.; Aldea, M.; Marinello, A.; Aredo, J.; Viros, A.; Besse, B.; Wakelee, H. A.; Blackhall, F.; Lindsay, C. R.; Malliri, A.
10.1101/2023.09.20.558592 — cancer biology — Posted on 2023-09-22
1478 Divide-and-conquer quantum algorithm for hybrid de novo genome assembly of short and long reads
Fang, J.-K.; Lin, Y.-F.; Huang, J.-H.; Chen, Y.; Fan, G.-M.; Sun, Y.; Feng, G.; Guo, C.; Meng, T.; Zhang, Y.; Xu, X.; Xiang, J.; Li, Y.
10.1101/2023.09.19.558544 — bioinformatics — Posted on 2023-09-22
1479 A fine-scale genetic map of the Japanese population
Takayama, J.; Makino, S.; Funayama, T.; Ueki, M.; Narita, A.; Murakami, K.; Orui, M.; Ishikuro, M.; Obara, T.; Kuriyama, S.; Yamamoto, M.; Tamiya, G.
10.1101/2023.09.19.558557 — genetics — Posted on 2023-09-22
1480 Ageing-related defects in macrophage function are driven by MYC and USF1 transcriptional programmes
Moss, C. E.; Johnston, S.; Clements, M.; Codd, V.; Hamby, S.; Goodall, A. H.; Desmukh, S.; Sudbery, I. M.; Coca, D.; Wilson, H. L.; Kiss-Toth, E.
10.1101/2023.09.20.558643 — immunology — Posted on 2023-09-22
1482 AgRP neuron activity promotes associations between sensory and nutritive signals to guide flavor preference
Nyema, N. T.; McKnight, A. D.; Vargas-Elvira, A. G.; Schneps, H. M.; Gold, E. G.; Myers, K. P.; Alhadeff, A. L.
10.1101/2023.09.19.558483 — neuroscience — Posted on 2023-09-22
1483 Hippocampal Ripples linked to Declarative Memory Judgments in Children
Norman, Y.; Dorfmuller, G.; Taussig, D.; Dorison, N.; Fohlen, M.; Chipaux, M.; Ferrand-Sorbets, S.; Bulteau, C.; Harel, M.; Malach, R.; Levy, M.
10.1101/2023.09.19.558300 — neuroscience — Posted on 2023-09-22
1491 Ventrointermediate thalamic stimulation improves motor learning in humans
Voegtle, A.; Terzic, L.; Farahat, A.; Hartong, N.; Galazky, I.; Hinrichs, H.; Nasuto, S. J.; de Oliveira Andrade, A.; Knight, R. T.; Ivry, R. B.; Voges, J.; Deliano, M.; Buentjen, L.; Sweeney-Reed, C. M.
10.1101/2023.09.19.558378 — neuroscience — Posted on 2023-09-22
1493 A draft of human N-glycans of glycoRNA
bi, m.; Zhang, Z.; Wang, T.; Liang, H.; TIAN, Z.
10.1101/2023.09.18.558371 — systems biology — Posted on 2023-09-22
1495 Consistent specificity and efficiency of tamoxifen-mediated cre induction across ages
Kellogg, C. M.; Pham, K.; Ko, S.; Cox, J. E. J.; Machalinski, A. H.; Stout, M. B.; Sharpe, A. L.; Beckstead, M. J.; Chucair-Elliott, A. J.; Ocanas, S. R.; Freeman, W. M.
10.1101/2023.09.19.558482 — genomics — Posted on 2023-09-22
1496 Disentangling non-random structure from random placement when estimating β-diversity through space or time
McGlinn, D.; Blowes, S. A.; Dornelas, M.; Engel, T.; Martins, I. S.; Shimadzu, H.; Gotelli, N. J.; Magurran, A.; McGill, B.; Chase, J. M.
10.1101/2023.09.19.558467 — ecology — Posted on 2023-09-22
1499 Mineralocorticoid receptor-independent activation of ENaC in bile duct ligated mice
Wang, X.-P.; Mutchler, S. M.; Carrisoza-Gaytan, R.; Al-bataineh, M.; Baty, C. J.; Vandevender, A.; Srinivasan, P.; Tan, R. J.; Jurczak, M. J.; Satlin, L. M.; Kashlan, O. B.
10.1101/2023.09.19.558474 — physiology — Posted on 2023-09-22
1500 Cancer immunotherapy responses persist after lymph node resection
Zhou, H.; Baish, J. W.; O'Melia, M. J.; Darragh, L. B.; Specht, E.; Czapla, J.; Lei, P.-j.; Menzel, L.; Rajotte, J. J.; Nikmaneshi, M. R.; Razavi, M. S.; Vander Heiden, M. G.; Ubellacker, J. M.; Munn, L. L.; Boland, G. M.; Cohen, S.; Karam, S. D.; Padera, T. P.
10.1101/2023.09.19.558262 — cancer biology — Posted on 2023-09-22
1505 Rapid and dynamic evolution of a giant Y chromosome in Silene latifolia
Akagi, T.; Fujita, N.; Masuda, K.; Shirasawa, K.; Nagaki, K.; Horiuchi, A.; Kuwada, E.; Kunou, R.; Nakamura, K.; Ikeda, Y.; Ushijima, K.; Charlesworth, D.
10.1101/2023.09.21.558759 — genetics — Posted on 2023-09-22
1507 Protein Kinase A Inhibition Epigenetically Silences Ren1
Smith, J. P.; Paxon, R.; Medrano, S.; Sheffield, N. C.; Sequeira-Lopez, M. L. S.; Gomez, R. A.
10.1101/2023.09.19.558267 — genomics — Posted on 2023-09-22
1508 A paleogenomic investigation of overharvest implications in an endemic wild reindeer subspecies
Kellner, F. L.; Le Moullec, M.; Ellegaard, M. R.; Rosvold, J.; Peeters, B.; Burnett, H. A.; Pedersen, A. O.; Brealey, J. C.; Dussex, N.; Bieker, V. C.; Hansen, B. B.; Martin, M. D.
10.1101/2023.09.21.558762 — genomics — Posted on 2023-09-22
1509 Multi-signal regulation of the GSK-3β homolog Rim11 governs meiosis entry in yeast
Kociemba, J.; Joergensen, A. C. S.; Tadic, N.; Harris, A.; Sideri, T.; Chan, W. Y.; Ibrahim, F.; Unal, E.; Skehel, M.; Shahrezaei, V.; Arguello-Miranda, O.; van Werven, F. J.
10.1101/2023.09.21.558844 — molecular biology — Posted on 2023-09-22
1510 Non-linear input-output relationships in the subthalamic nucleus of Parkinson's patients
Liu, X.; Glowinsky, S.; Abadi, H.; Leon, J. F.; Wang, W.; Arkadir, D.; Israel, Z.; Bergman, H.; Guang, J.
10.1101/2023.09.18.558149 — neuroscience — Posted on 2023-09-22
1511 Reconstruction of single cell lineage trajectories and identification of diversity in fates during the epithelial-to-mesenchymal transition
Cheng, Y.-C.; Zhang, Y.; Tripathi, S.; BV, H.; Jolly, M. K.; Schiebinger, G.; Levine, H.; McDonald, T. O.; Michor, F.
10.1101/2023.09.19.558325 — systems biology — Posted on 2023-09-22
1512 Systematic Profiling of Ale Yeast Protein Dynamics across Fermentation and Repitching
Garge, R. K.; Geck, R. C.; Armstrong, J. O.; Dunn, B.; Boutz, D. R.; Battenhouse, A.; Leutert, M.; Dang, V.; Jiang, P.; Kwiatkowski, D.; Peiser, T.; McElroy, H.; Marcotte, E. M.; Dunham, M. J.
10.1101/2023.09.21.558736 — systems biology — Posted on 2023-09-22
1513 Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation
Baron, M.; Tagore, M.; Wall, P.; Zheng, F.; Barkley, D.; Yanai, I.; Yang, J.; Kiuru, M.; White, R.; Ideker, T.
10.1101/2023.09.19.558457 — systems biology — Posted on 2023-09-22
1516 A muscle hypertrophy-derived myokine reprograms the stromal vascular fractions differentiation towards thermogenic adipocytes in subcutaneous adipose tissue
Yao, X.; Mai, X.; Tian, Y.; Liu, Y.; Jin, G.; Li, Z.; Chen, S.; Dai, X.; Jin, X.; Huang, L.; Han, M.; Fan, Z.; Xiao, L.; Pan, G.; Pan, X.; Lin, Z.; Li, X.; Sun, J.; Ou, J.; Chen, H.; Xie, L.
10.1101/2023.09.20.558627 — physiology — Posted on 2023-09-22
1519 Factor XI localization in human deep venous thrombus and function of activated factor XI on venous thrombus formation and hemostasis in rabbit
Oguri, N.; Gi, T.; Nakamura, E.; Maekawa, K.; Furukoji, E.; Okawa, H.; Sho, K.; Horiuchi, S.; Sakae, T.; Azuma, M.; Asada, Y.; Yamashita, A.
10.1101/2023.09.19.558346 — pathology — Posted on 2023-09-22
1521 A spatially mapped gene expression signature for intestinal stem-like cells identifies high-risk precursors of gastric cancer
Huang, R. J.; Wichmann, I. A.; Su, A.; Sathe, A.; Shum, M. V.; Grimes, S. M.; Meka, R.; Almeda, A.; Bai, X.; Shen, J.; Nguyen, Q.; Amieva, M. R.; Hwang, J. H.; Ji, H.
10.1101/2023.09.20.558462 — cancer biology — Posted on 2023-09-22
1522 Testing Adaptive Therapy Protocols using Gemcitabine and Capecitabine on a Mouse Model of Endocrine-Resistant Breast Cancer
SEYEDI, S.; Teo, R.; Foster, L.; Saha, D.; Mina, L.; Northfelt, D.; Anderson, K. S.; Shibata, D.; Gatenby, R.; Cisneros, L.; Troan, B.; Anderson, A. R. A.; Maley, C. C.
10.1101/2023.09.18.558136 — cancer biology — Posted on 2023-09-22
1524 Tunable PhenoCycler Imaging of the Murine Pre-Clinical Tumour Microenvironments
Abraham, M. J.; Goncalves, C.; McCallum, P.; Gupta, V.; Preston, S. E. J.; Huang, F.; Chou, H.; Gagnon, N.; Johnson, N. A.; Miller, W. H.; Mann, K. K.; del Rincon, S. V.
10.1101/2023.09.18.558299 — cancer biology — Posted on 2023-09-22
1525 Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors
van Belzen, I. A. E. M.; van Tuil, M. C.; Badloe, S.; Janse, A.; Verwiel, E. T. P.; Santoso, M.; de Vos, S.; Baker-Hernandez, J.; Kerstens, H. H. D.; Solleveld-Westerink, N.; Meister, M. T.; Drost, J.; van den Heuvel-Eibrink, M. M.; Merks, J. H. M.; Molenaar, J. J.; Peng, W. C.; Tops, B. B. J.; Holstege, F. C. P.; Kemmeren, P.; Hehir-Kwa, J. Y.
10.1101/2023.09.19.558241 — cancer biology — Posted on 2023-09-22
1526 Multiple Intermediates in the Detergent-Induced Fusion of Lipid Vesicles
Dresser, L. G.; Kunstmann, C.; Conteduca, D.; Johnson, S.; Penedo, C.; Leake, M. C.; Quinn, S. D.
10.1101/2023.09.21.558601 — biophysics — Posted on 2023-09-22
1527 ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome
Hirsch, P.; Tagirdzhanov, A.; Kushnareva, A.; Olkhovskii, I.; Graf, S.; Schmartz, G. P.; Mueller, R.; Keller, A.; Gurevich, A.
10.1101/2023.09.18.558305 — bioinformatics — Posted on 2023-09-22
1528 Low-input and single-cell methods for Infinium DNA methylation BeadChips
Lee, S. M.; Loo, C. E.; Prasasya, R. D.; Bartolomei, M. S.; Kohli, R. M.; Zhou, W.
10.1101/2023.09.18.558252 — bioinformatics — Posted on 2023-09-22
1529 Advancing GABA-edited MRS Research through a Reconstruction Challenge
Berto, R. P.; Bugler, H.; Dias, G.; Oliveira, M.; Ueda, L.; Dertkigil, S.; Costa, P. D. P.; Rittner, L.; Merkofer, J. P.; Van de Sande, D. M. J.; Amirrajab, S.; Drenthen, G. S.; Veta, M.; Jansen, J. F. A.; Breeuwer, M.; van Sloun, R. J. G.; Qayyum, A.; Rodero, C.; Niederer, S.; Souza, R.; Harris, A. D.
10.1101/2023.09.21.557971 — bioengineering — Posted on 2023-09-22
1530 MarrowDLD: a microfluidic method for label-free retrieval of fragile bone marrow cells
Porro, G.; Sarkis, R.; Obergozo, C.; Godot, L.; Amato, F.; Humbert, M.; Naveiras, O.; Guiducci, C.
10.1101/2023.09.22.558939 — bioengineering — Posted on 2023-09-22
1533 Redox Active Plant Phenolic, Acetosyringone, for Electrogenetic Signaling
Zakaria, F. R.; Chen, C.-Y.; Li, J.; Wang, S. P.; Payne, G. F.; Bentley, W. E.
10.1101/2023.09.20.558642 — bioengineering — Posted on 2023-09-22
1535 Flexible 3-D Electrochemical Impedance Spectroscopy Sensors Incorporating Phase Delay for Comprehensive Characterization of Atherosclerosis
Chen, M.; Neverova, N.; Xu, S.; Suwannaphoom, K.; Lluri, G.; Tamboline, M.; Duarte, S.; Fishbein, M. C.; Luo, Y.; Packard, R. R.
10.1101/2023.09.20.558681 — bioengineering — Posted on 2023-09-22
1538 Computational modeling of dorsal root ganglion stimulation using an Injectrode
Bhowmick, S.; Graham, R. D.; Verma, N.; Trevathan, J. K.; Franke, M.; Nieuwoudt, S.; Fisher, L. E.; Shoffstall, A. J.; Weber, D. J.; Ludwig, K. A.; Lempka, S.
10.1101/2023.09.20.558675 — bioengineering — Posted on 2023-09-22
1540 Peripheral Blood Single-Cell Sequencing Uncovers Common and Specific Immune Aberrations in Fibrotic Lung Diseases
Zhao, A. Y.; Unterman, A.; Abu Hussein, N.; Sharma, P.; Flint, J.; Yan, X.; Adams, T. S.; Justet, A.; Sumida, T. S.; Zhao, J.; Schupp, J. C.; Raredon, M. S. B.; Ahangari, F. C.; Zhang, Y.; Buendia-Roldan, I.; Adegunsoye, A.; Sperling, A. I.; Prasse, A.; Ryu, C.; Herzog, E.; Selman, M.; Pardo, A.; Kaminski, N.
10.1101/2023.09.20.558301 — genomics — Posted on 2023-09-22
1543 PAI-1 Deficiency Drives Pulmonary Vascular Smooth Muscle Remodeling and Pulmonary Hy-pertension
Kudryashova, T. V.; Zaitsev, S. V.; Jiang, L.; Buckley, B. J.; McGuckin, J. P.; Goncharov, D.; Zhyvylo, I.; Lin, D.; Newcomb, G.; Piper, B.; Bogamuwa, S.; Saiyed, A.; Teos, L.; Ranson, M.; Wolters, P.; Kelso, M. J.; Poncz, M.; DeLisser, H. M.; Cines, D. B.; Goncharova, E. A.; Farkas, L.; Stepanova, V.
10.1101/2023.09.21.558893 — cell biology — Posted on 2023-09-22
1544 The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity
Mamar, H.; Fajka-Boja, R.; Morocz, M.; Jurado, E. P.; Zentout, S.; Mihut, A.; Kopasz, A. G.; Merey, M.; Smith, R.; Haracska, L.; Huet, S.; Timinszky, G.
10.1101/2023.09.21.558850 — cell biology — Posted on 2023-09-22
1545 Dominant CIZ1 fragments drive epigenetic instability and are expressed in early stage cancers
Turvey, G.; Lopez de Alba, E.; Stewart, E.; Byrom, L.; Cook, H.; Sofi, S.; Alati, A.; Ainscough, J.; Mason, A. S.; Antson, A. A.; Coverley, D.
10.1101/2023.09.22.558821 — cell biology — Posted on 2023-09-22
1546 Biallelic variants in LARS1 induce steatosis in developing zebrafish liver via enhanced autophagy
Inoue, M.; Sebastian, W. A.; Sonoda, S.; Miyahara, H.; Shimizu, N.; Shiraishi, H.; Maeda, M.; Yanagi, K.; Kaname, T.; Hanada, R.; Hanada, T.; Ihara, K.
10.1101/2023.09.21.558924 — cell biology — Posted on 2023-09-22
1550 The Role of Vitamin D in Emiliania huxleyi: A Microalgal Perspective on UV-B Exposure
Eliason, O.; Malitsky, S.; Panizel, I.; Feldmesser, E.; Sperfeld, M.; Segev, E.
10.1101/2023.09.21.558789 — microbiology — Posted on 2023-09-22
1551 Phage-induced efflux down-regulation boosts antibiotic efficacy
Kraus, S.; Lapinska, U.; Chawla, K.; Baker, E.; Attrill, E.; ONeill, P.; Farbos, A.; Jeffries, A.; Galyov, E.; Korbsrisate, S.; Barnes, K.; Harding, S.; Tsaneva-Atanasova, K.; Blaskovich, M.; Pagliara, S.
10.1101/2023.09.21.558807 — microbiology — Posted on 2023-09-22
1555 OPTIMAL: An OPTimsed Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration
Hunter, B.; Nicorescu, I.; Foster, E.; McDonald, D.; Hulme, G.; Fuller, A.; Thomson, A.; Goldsborough, T.; Hilkens, C.; Majo, J.; Milross, L.; Fisher, A. J.; Bankhead, P.; Wills, J. W.; Rees, P.; Filby, A.; Merces, G.
10.1101/2023.02.21.526083 — bioinformatics — Posted on 2023-09-22
1557 Layer 1 of somatosensory cortex: An important site for input to a tiny cortical compartment
Ledderose, J.; Zolnik, T. A.; Toumazou, M.; Trimbuch, T.; Rosenmund, C.; Eickholt, B. J.; Jaeger, D.; Larkum, M. E.; Sachdev, R.
10.1101/2021.11.26.469979 — neuroscience — Posted on 2023-09-22
1558 Predicting bonds between collagens -A multiple alignment approach
Wesp, V.; Scholz, L.; Ziermann-Canabarro, J. M.; Schuster, S.; Stark, H.
10.1101/2023.08.25.554753 — systems biology — Posted on 2023-09-22
1559 Pheromone-dependent olfaction bidirectionally regulates muscle extracellular vesicles formation
Szczepanska, A.; Banasiak, K.; Kołodziejska, K.; Yu, J.; Ibrahim, A. T.; Adamkiewicz, L.; Schroeder, F. C.; Pokrzywa, W.; Turek, M.
10.1101/2022.12.22.521669 — physiology — Posted on 2023-09-22
1567 Detecting Differential Alternative Splicing in Mass Spectrometry-based Proteomics Data
Ammar, C.; Csaba, G.; Hadziahmetovic, A.; Vasilopoulou, C.; Gruber, M.; Mann, M.; Zimmer, R.
10.1101/2023.09.19.558203 — bioinformatics — Posted on 2023-09-22
1568 Genome-enabled analysis of population dynamics and virulence associated loci in the oat crown rust fungus Puccinia coronata f. sp. avenae
Hewitt, T. C.; Henningsen, E. C.; Pereira, D.; McElroy, K.; Nazareno, E. S.; Dugyala, S.; Nguyen-Phuc, H.; Li, F.; Miller, M. E.; Visser, B.; Pretorius, Z. A.; Boshoff, W. H.; Sperschneider, J.; Stukenbrock, E. H.; Kianian, S. F.; Dodds, P. N.; Figueroa, M.
10.1101/2023.09.18.557855 — genomics — Posted on 2023-09-22
1569 Post-meiotic mechanism of facultative parthenogenesis in gonochoristic whiptail lizard species.
Ho, D. V.; Tormey, D.; Odell, A.; Newton, A. A.; Schnittker, R. R.; Baumann, D. P.; Neaves, W. B.; Schroeder, M. R.; Sigauke, R. F.; Barley, A. J.; Baumann, P.
10.1101/2023.09.21.558237 — genomics — Posted on 2023-09-22
1570 Dissecting Factors Underlying Phylogenetic Uncertainty Using Machine Learning Models
Rosas-Puchuri, U.; Duarte-Ribeiro, E.; Khanmohammadi, S.; Arcila, D.; Orti, G.; Betancur-R., R.
10.1101/2023.09.20.558635 — evolutionary biology — Posted on 2023-09-22
1574 Evidence for managing herbivores for reef resilience
Donovan, M. K.; Counsell, C. W. W.; Donahue, M. J. K.; Lecky, J.; Gajdzik, L.; Marcoux, S. D.; Sparks, R. T.; Teague, C.
10.1101/2023.09.19.557828 — ecology — Posted on 2023-09-22
1576 Paternal starvation affects metabolic gene expression during zebrafish offspring development and life-long fitness
Jimenez-Gonzalez, A.; Ansaloni, F.; Nebendahl, C.; Alavioon, G.; Murray, D.; Robak, W.; Sanges, R.; Muller, F.; Immler, S.
10.1101/2023.09.22.557632 — developmental biology — Posted on 2023-09-22
1577 Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions
Yoshimura, S.; Shimada, R.; Kikuchi, K.; Kawagoe, S.; Abe, H.; Iisaka, S.; Fujimura, S.; Yasunaga, K.-i.; Usuki, S.; Tani, N.; Ohba, T.; Kondoh, E.; Saio, T.; Araki, K.; Ishiguro, K.-i.
10.1101/2023.09.19.557986 — developmental biology — Posted on 2023-09-22
1578 Mechanisms of type I interferon production by chicken TLR21
Guabiraba, R.; Rodrigues, D. R.; Manna, P. T.; Chollot, M.; Saint-Martin, V.; Trapp, S.; Oliveira, M.; Bryant, C. E.; Ferguson, B. J.
10.1101/2023.09.20.558228 — immunology — Posted on 2023-09-22
1579 Selective refueling of CAR T cells using ADA1 and 1 CD26 boosts antitumor immunity
Hu, Y.; Sarkar, A.; Song, K.; Michael, S.; Hook, M.; Wang, R.; Heczey, A.; Song, X.
10.1101/2023.09.18.557956 — immunology — Posted on 2023-09-22
1580 Network-guided Therapeutics to Differentiate Colorectal Cancer Stem Cells
Sinha, S.; Alcantara, J.; Perry, K.; Castillo, V.; Espinoza, C. R.; Taheri, S.; Vidales, E.; Tindle, C.; Adel, A.; Amirfakhri, S.; Sawires, J. R.; Yang, J.; Bouvet, M.; Sahoo, D.; Ghosh, P.
10.1101/2023.09.13.557628 — cancer biology — Posted on 2023-09-22
1581 A Multimodal Deep Learning Framework for Predicting PPI-Modulator Interactions
Sun, H.; Wang, J.; Wu, H.; Lin, S.; Chen, J.; Wei, J.; Lv, S.; Xiong, Y.; Wei, D.-Q.
10.1101/2023.08.03.551827 — bioinformatics — Posted on 2023-09-22
1585 Activity-induced gene expression in the human brain
Chatterjee, S.; Park, B. J.; Vanrobaeys, Y.; Heiney, S. A.; Rhone, A. E.; Nourski, K. V.; Langmack, L.; Mukherjee, U.; Kovach, C. K.; Kocsis, Z.; Kikuchi, Y.; Petkov, C. I.; Hefti, M. M.; Bahl, E.; Michaelson, J. J.; Kawasaki, H.; Oya, H.; Howard, M. A.; Nickl-Jockschat, T.; Lin, L.-C.; Abel, T.
10.1101/2023.09.21.558812 — neuroscience — Posted on 2023-09-22
1586 Theta mediated dynamics of human hippocampal-neocortical learning systems in memory formation and retrieval
Gattas, S.; Larson, M. S.; Mnatsakanyan, L.; Sen-Gupta, I.; Vadera, S.; Swindlehurst, A. L.; Rapp, P.; Lin, J.; Yassa, M. A.
10.1101/2023.09.20.558688 — neuroscience — Posted on 2023-09-22
1591 Multi-omics analysis reveals signatures of selection and loci associated with complex traits in pigs
Yi, G.; Liu, L.; Yao, Y.; Liu, Y.; Li, J.; Yang, Y.; Fang, L.; Mo, D.; Zhang, L.; Liu, Y.; Niu, Y.; Wang, L.; Qu, X.; Pan, Z.; Wang, L.; Chen, M.; Fan, X.; Chen, Y.; Zhang, Y.; Li, X.; Wang, Z.; Tang, Y.; Huang, H.; Yuan, P.; Liao, Y.; Li, X.; Yin, Z.; Liu, D.; Zhang, D.; Zhou, Q.; Wu, W.; Jiang, J.; Gao, Y.; Liu, G. E.; Wang, L.; Chen, Y.; Groenen, M.; Tang, Z.
10.1101/2023.09.19.558553 — genomics — Posted on 2023-09-21
1592 Integrative PTEN Enhancer Discovery Reveals a New Model of Enhancer Organization
Cerda-Smith, C.; Hutchinson, H. M.; Liu, A.; Goel, V. Y.; Sept, C.; Kim, H.; Casani-Galdon, S.; Burkman, K. G.; Bassil, C. F.; Hansen, A. S.; Aryee, M. J.; Johnstone, S. E.; Eyler, C. E.; Wood, K. C.
10.1101/2023.09.20.558459 — genomics — Posted on 2023-09-22
1595 Radial glia promote microglial development through integrin aVb8 -TGFb1 signaling
McKinsey, G. L.; Santander, N.; Zhang, X.; Kleemann, K.; Tran, L.; Katewa, A.; Conant, K.; Barraza, M.; Waddell, K.; Lizama, C. O.; La Russa, M.; Koo, J. H.; Lee, H.; Mukherjee, D.; Paidassi, H.; Anton, E. S.; Atabai, K.; Sheppard, D.; Butovsky, O.; Arnold, T. D.
10.1101/2023.07.13.548459 — immunology — Posted on 2023-09-22
1598 Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function.
Sportelli, L.; Eisenberg, D. P.; Passiatore, R.; D'Ambrosio, E.; Antonucci, L. A.; Chen, Q.; Czarapata, J.; Goldman, A. L.; Gregory, M.; Griffiths, K.; Hyde, T. M.; Kleinman, J. E.; Pardinas, A. F.; Parihar, M.; Popolizio, T.; Rampino, A.; Shin, J. H.; Veronese, M.; Ulrich, W. S.; Zink, C. F.; Bertolino, A.; Howes, O. D.; Berman, K. F.; Weinberger, D.; Pergola, G.
10.1101/2023.09.20.558594 — neuroscience — Posted on 2023-09-21
1599 Metabotropic signaling within somatostatin interneurons regulates thalamocortical inputs during development
Dwivedi, D.; Dumontier, D.; Sherer, M.; Lin, S.; Mirow, A. M.; Qiu, Y.; Xu, Q.; Liebman, S. A.; Joseph, D.; Datta, S. R.; Fishell, G.; Pouchelon, G.
10.1101/2023.09.21.558862 — neuroscience — Posted on 2023-09-22
1600 Position-independent refinement of vagus motor neuron wiring
Kaneko, T.; Boulanger-Weill, J.; Isabella, A. J.; Moens, C. B.
10.1101/2023.09.11.557289 — neuroscience — Posted on 2023-09-22
1601 Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens
Vollenweider, V.; Rehm, K.; Chepkirui, C.; Perez-Berlanga, M.; Polymenidou, M.; Piel, J.; Bigler, L.; Kuemmerli, R.
10.1101/2023.07.18.549568 — microbiology — Posted on 2023-09-21
1605 Effects of protein G-quadruplex interactions on phase transitions and protein aggregation
Sahoo, B.; Kocman, V.; Clark, N.; Myers, N.; Deng, X.; Wong, E. L.; Yang, H. J.; Kotar, A.; Guzman, B. B.; Dominguez, D. C.; Plavec, J.; Bardwell, J. C.
10.1101/2023.09.21.558871 — biochemistry — Posted on 2023-09-21
1606 C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA
Consalvo, C. D.; Aderounmu, A. M.; Donelick, H. M.; Aruscavage, P. J.; Eckert, D. M.; Shen, P. S.; Bass, B. L.
10.1101/2023.09.21.558868 — biochemistry — Posted on 2023-09-21
1607 Tangled up in fibers: How a lytic polysaccharide monooxygenase binds its chitin substrate
Sorensen, H. V.; Montserrat-Canals, M.; Prevost, S.; Vaaje-Kolstad, G.; Bjerregaard-Andersen, K.; Lund, R.; Krengel, U.
10.1101/2023.09.21.558757 — biochemistry — Posted on 2023-09-21
1608 Light-sensitive phosphorylation regulates enzyme activity and filament assembly of human IMPDH1 retinal splice variants
Calise, S. J.; O'Neill, A. G.; Burrell, A. L.; Dickinson, M. S.; Molfino, J.; Clarke, C.; Quispe, J.; Sokolov, D.; Buey, R. M.; Kollman, J. M.
10.1101/2023.09.21.558867 — biochemistry — Posted on 2023-09-21
1609 pyHiM, a new open-source, multi-platform software package for spatial genomics based on multiplexed DNA-FISH imaging
Devos, X.; Fiche, J.-B.; Bardou, M.; Messina, O.; Houbron, C.; Gurgo, J.; Schaeffer, M.; Goetz, M.; Walter, T.; Mueller, F.; Nollmann, M.
10.1101/2023.09.19.558412 — genomics — Posted on 2023-09-21
1610 High standing diversity masks extreme genetic erosion in a declining snake.
Pozzi, A. V.; Owens, J. B.; Üveges, B.; Major, T.; Morris, E.; Graham, S.; Togridou, A.; Papadopulos, A. S. T.; Wüster, W.; Barlow, A.
10.1101/2023.09.19.557540 — genomics — Posted on 2023-09-21
1611 Fishing for a reelGene: evaluating gene models with evolution and machine learning
Schulz, A. J.; Zhai, J.; AuBuchon-Elder, T.; El-Walid, M.; Ferebee, T. H.; Gilmore, E. H.; Hufford, M. B.; Johnson, L. C.; Kellogg, E.; La, T.; Long, E.; Miller, Z. R.; Romay, C.; Seetharam, A. S.; Stitzer, M. C.; Wrightsman, T.; Buckler, E. S.; Monier, B.; Hsu, S.-K.
10.1101/2023.09.19.558246 — genomics — Posted on 2023-09-21
1618 Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging
Lopez-Lee, C.; Kodama, L.; Fan, L.; Wong, M. Y.; Foxe, N. R.; Ijaz, L.; Yu, F.; Ye, P.; Zhu, J.; Norman, K.; Torres, E. R.; Kim, R.; Mousa, G. A.; Dubal, D.; Liddelow, S.; Luo, W.; Gan, L.
10.1101/2023.09.19.558439 — neuroscience — Posted on 2023-09-21
1620 When the heart meets the mind Exploring the brain-heart interaction during time perception
Khoshnoud, S.; Leitritz, D.; Cinar Bozdag, M.; Alvarez Igarzabal, F.; Noreika, V.; Wittmann, M.
10.1101/2023.09.20.558404 — neuroscience — Posted on 2023-09-21
1622 Auditory selective attention during a working memory task with melodies: a MEG study
de la Chapelle, A.; Serres-Blain, S.; ElShafei, A.; Schwartz, D.; Daligault, S.; Jung, J.; Ruby, P.; Caclin, A.; Bidet-Caulet, A.
10.1101/2023.09.19.558422 — neuroscience — Posted on 2023-09-21
1624 Estrogen-dependent development and transcriptome regulation of the lateral septal kisspeptin system
Szentkiralyi-Toth, S.; Gocz, B.; Takacs, S.; Sarvari, M.; Farkas, I.; Skrapits, K.; Rumpler, E.; Poliska, S.; Wittmann, G.; Mohacsik, P.; Gereben, B.; Fekete, C.; Hrabovszky, E.
10.1101/2023.09.20.557932 — neuroscience — Posted on 2023-09-21
1626 Data from Entomological Collections of Aedes (Diptera: Culicidae) in a post-epidemic area of Chikungunya, City of Kinshasa, Democratic Republic of Congo
Nsabatien, V.; Zanga, J.; Agossa, F.; Mvuama, N.; Bamba, M.; Mansiangi, O.; Mbashi, L.; Mvudi, V.; Diza, G.; Kantin, D.; Basosila, N.; Lukoki, H.; Bokulu, A.; Bosulu, C.; Bukaka, E.; Nagahuedi, J.; Palata, J. C.; Metelo, E.
10.1101/2023.09.20.558445 — zoology — Posted on 2023-09-21
1627 A genetic circuit on a single DNA molecule as autonomous dissipative nanodevice
Greiss, F.; Lardon, N.; Schutz, L.; Barak, Y.; Daube, S. S.; Weinhold, E.; Noireaux, V.; Bar-Ziv, R.
10.1101/2023.09.21.558768 — synthetic biology — Posted on 2023-09-21
1635 Genetic diversity of the Atacama Desert shrub Huidobria chilensis in the context of geography and climate
Bechir Ferchichi, K.; Boehnert, T.; Ritter, B.; Harpke, D.; Stoll, A.; Morales, P.; Fiedler, S.; Mu, F.; Bechteler, J.; Muenker, C.; Koch, M. A.; Wiehe, T.; Quandt, D.
10.1101/2023.09.20.558398 — genetics — Posted on 2023-09-21
1636 A genome-scale Opisthokonta tree of life: toward phylogenomic resolution of ancient divergences
Liu, H.; Steenwyk, J. L.; Zhou, X.; Schultz, D. T.; Kocot, K. M.; Shen, X.-X.; Rokas, A.; Li, Y.
10.1101/2023.09.20.556338 — evolutionary biology — Posted on 2023-09-21
1637 Testing the predictions of reinforcement: long-term empirical data from a damselfly mosaic hybrid zone
Arce-Valdes, L. R.; Ballen-Guapacha, A. V.; Torres, A. R.; Rios, J. R. C.; Wellenreuther, M.; Hansson, B.; Guillen, R. A. S.
10.1101/2023.09.20.537982 — evolutionary biology — Posted on 2023-09-21
1638 Hybridization and its impact on the ontogenetic allometry of skulls in macaques
Ito, T.; Kimura, R.; Wakamori, H.; Tanaka, M.; Tezuka, A.; Nagano, A. J.; Hamada, Y.; kawamoto, Y.
10.1101/2023.04.19.536293 — evolutionary biology — Posted on 2023-09-21
1639 Protection promotes energetically efficient structures in marine communities
Tabi, A.; Gilarranz, L. J.; Wood, S. A.; Dunne, J. A.; Saavedra, S.
10.1101/2022.06.02.494503 — ecology — Posted on 2023-09-21
1640 Sucrose taste receptors differ in larval and adult stages of a moth
Zhang, S.-S.; Wang, P.-C.; Ning, C.; Yang, K.; Li, G.-C.; Cao, L.-L.; Huang, L.-Q.; Wang, C.-Z.
10.1101/2023.09.19.558417 — ecology — Posted on 2023-09-21
1641 An amino acid-resolution interactome for motile cilia illuminates the structure and function of ciliopathy protein complexes
McCafferty, C. L.; Papoulas, O.; Lee, C.; Bui, K. H. L.; Taylor, D. W.; Marcotte, E. M.; Wallingford, J. B.
10.1101/2023.07.09.548259 — cell biology — Posted on 2023-09-21
1643 Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs
Iwasaki, S.; Saito, H.; Handa, Y.; Chen, M.; Schneider-Poetsch, T.; Shichino, Y.; Takahashi, M.; Romo, D.; Yoshida, M.; Furstner, A.; Ito, T.; Fukuzawa, K.
10.1101/2023.09.21.558742 — molecular biology — Posted on 2023-09-21
1644 Clr4SUV39H1 ubiquitination and non-coding RNA mediate transcriptional silencing via heterochromatic phase transitions
Kim, H.-S.; Roche, B.; Bhattacharjee, S.; Todeschini, L.; Chang, A.-Y.; Hammell, C.; Verdel, A.; Martienssen, R. A.
10.1101/2021.01.08.425919 — molecular biology — Posted on 2023-09-21
1646 Soft rot pathogen Dickeya dadantii 3937 produces tailocins resembling the tails of Enterobacteria bacteriophage P2
Borowicz, M.; Krzyzanowska, D. M.; Narajczyk, M.; Sobolewska, M.; Rajewska, M.; Czaplewska, P.; Wegrzyn, K.; Czajkowski, R.
10.1101/2023.08.14.553165 — microbiology — Posted on 2023-09-21
1647 Anti-S-layer monoclonal antibodies impact Clostridioides difficile physiology
Hunault, L.; Auria, E.; England, P.; Deschamps, J.; Briandet, R.; Kremer, V.; Iannascoli, B.; Vidal-Maison, L.; Guo, C.; Macdonald, L.; Pechine, S.; Deneve-Larrazet, C.; Dupuy, B.; Gorochov, G.; Bruhns, P.; Sterlin, D.
10.1101/2023.09.21.558785 — microbiology — Posted on 2023-09-21
1648 HOCl-producing Electrochemical Bandages for Treating Pseudomonas aeruginosa-Infected Murine Wounds
Fleming, D.; Bozyel, I.; Ozdemir, D.; Otero, J. A.; Karau, M. J.; Anoy, M. M. I.; Koscianski, C.; Schuetz, A. N.; Greenwood-Quiantance, K. E.; Mandrekar, J. N.; Beyenal, H.; Patel, R.
10.1101/2023.09.20.558698 — microbiology — Posted on 2023-09-21
1649 Identification and targeting of microbial putrescine acetylation in bloodstream infections
Mayers, J. R.; Varon, J.; Zhou, R. R.; Daniel-Ivad, M.; Beaulieu, C.; Bholse, A.; Glasser, N. R.; Lichtenauer, F. M.; Ng, J.; Pinilla Vera, M.; Huttenhower, C.; Perrella, M. A.; Clish, C. B.; Zhao, S. D.; Baron, R. M.; Balskus, E. P.
10.1101/2023.09.21.558834 — microbiology — Posted on 2023-09-21
1651 A monoclonal antibody collection for C. difficile typing
Hunault, L.; England, P.; Barbut, F.; Iannascoli, B.; Godon, O.; Dejardin, F.; Thomas, C.; Dupuy, B.; Guo, C.; Macdonald, L.; Gorochov, G.; Sterlin, D.; Bruhns, P.
10.1101/2023.09.21.557191 — immunology — Posted on 2023-09-21
1652 Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells
Hargrave, K. E.; Worrell, J. C.; Pirillo, C.; Brennan, E.; Masdefiol Garriga, A.; Gray, J. I.; Purnell, T.; Roberts, E. W.; MacLeod, M. K.
10.1101/2023.09.19.558387 — immunology — Posted on 2023-09-21
1653 The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection
Wong, M. P.; Juan, E. Y.; Chelluri, S. S.; Wang, P.; Pahmeier, F.; Castillo-Rojas, B.; Blanc, S. F.; Biering, S. B.; Vance, R. E.; Harris, E.
10.1101/2023.09.21.558875 — immunology — Posted on 2023-09-21
1656 Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models.
Sumathipala, S. H.; Khan, S.; Kozol, R. A.; Araki, Y.; Syed, S.; Huganir, R. L.; Dallman, J.
10.1101/2023.09.20.557316 — neuroscience — Posted on 2023-09-21
1657 Etifoxine inhibits NLRP3 inflammasome activity in human and murine myeloid cells
Osmond, J. M.; Williams, J. B.; Matthews, P. M.; Owen, D. R.; Moore, C. S.
10.1101/2023.09.19.558428 — neuroscience — Posted on 2023-09-21
1658 Computational design of sequence-specific DNA-binding proteins
Glasscock, C. J.; Pecoraro, R.; McHugh, R.; Doyle, L. A.; Chen, W.; Boivin, O.; Lonnquist, B.; Na, E.; Politanska, Y.; Haddox, H. K.; Cox, D.; Norn, C.; Coventry, B.; Goreshnik, I.; Vafeados, D.; Lee, G. R.; Gordan, R.; Stoddard, B. L.; DiMaio, F.; Baker, D.
10.1101/2023.09.20.558720 — synthetic biology — Posted on 2023-09-21
1659 Treg cells drive MYCN-mediated immunosuppression and tumor aggressiveness in high-risk neuroblastoma
Qin, X.; Lam, A. K.; Zhang, X.; Sengupta, S.; Iorgulescu, B. J.; Zuo, T.; Floru, A. E.; Meara, G. K.; Lloyd, k.; Kwok, L. A.; Smith, K. S.; Nagaraju, T. R.; Meijers, R.; Ceol, C.; Liu, C.-T.; Alexandrescu, S.; Wu, C. J.; Keskin, D.; George, R. E.; Feng, H.
10.1101/2022.10.03.510561 — cancer biology — Posted on 2023-09-21
1660 Membrane binding and pore formation is Ca2+-dependent for the Clostridioides difficile binary toxin
Abeyawardhane, D. L.; Sevdalis, S. E.; Adipietro, K. A.; Godoy-Ruiz, R.; Varney, K. M.; Nawaz, I. F.; Spittel, A. X.; Rustandi, R. R.; Silin, V. I.; des Georges, A.; Pozharski, E.; Weber, D. J.
10.1101/2023.08.18.553786 — biophysics — Posted on 2023-09-21
1661 Tuning of B12 photochemistry in the CarH photoreceptor to avoid radical photoproducts
Camacho, I. S.; Wall, E.; Sazanovich, I. V.; Gozzard, E.; Towrie, M.; Hunt, N. T.; Hay, S.; Jones, A. R.
10.1101/2023.08.11.552799 — biophysics — Posted on 2023-09-21
1663 Recognition of highly branched N-glycans of the porcine whipworm by the immune system
Eckmair, B.; Gao, C.; Mehta, A. Y.; Dutkiewicz, Z.; Vanbeselaere, J.; Cummings, R. D.; Paschinger, K.; Wilson, I. B. H.
10.1101/2023.09.21.557549 — biochemistry — Posted on 2023-09-21
1666 Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models
Dumont, B. L.; Gatti, D. M.; Ballinger, M. A.; Lin, D.; Phifer-Rixey, M.; Sheehan, M. J.; Suzuki, T.; Wooldridge, L. K.; Opoku Frempong, H.; Churchill, G. A.; Lutz, C. M.; Rosenthal, N.; White, J. K.; Nachman, M.
10.1101/2023.09.21.558738 — genetics — Posted on 2023-09-21
1667 MUSSEL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups
Jin, J.; Zhan, J.; Zhang, J.; Zhao, R.; O'Connell, J.; Jiang, Y.; 23andMe Research Team, ; Buyske, S.; Gignoux, C. R.; Haiman, C. A.; Kenny, E.; Kooperberg, C.; North, K. E.; Koelsch, B. L.; Wojcik, G. L.; Zhang, H.; Chatterjee, N.
10.1101/2023.04.12.536510 — genetics — Posted on 2023-09-21
1668 Stable population structure in Europe since the Iron Age, despite high mobility
Antonio, M. L.; Weiss, C. L.; Gao, Z.; Sawyer, S.; Oberreiter, V.; Moots, H. M.; Spence, J. P.; Cheronet, O.; Zagorc, B.; Praxmarer, E.; Ozdogan, K. T.; Demetz, L.; Gelabert, P.; Fernandes, D.; Lucci, M.; Alihodzic, T.; Amrani, S.; Avetisyan, P.; Baillif-Ducros, C.; Bedic, Z.; Bertrand, A.; Bilic, M.; Bondioli, L.; Borowka, P.; Botte, E.; Burmaz, J.; Buzanic, D.; Candilio, F.; Cvetko, M.; De Angelis, D.; Drnic, I.; Elschek, K.; Fantar, M.; Gaspari, A.; Gasperetti, G.; Genchi, F.; Golubovic, S.; Hukelova, Z.; Jankauskas, R.; Vuckovic, K. J.; Jeremic, G.; Kaic, I.; Kazek, K.; Khachatryan, H.; Kh
10.1101/2022.05.15.491973 — genetics — Posted on 2023-09-21
1669 Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in Drosophila
Erkosar, B.; Dupuis, C.; Cavigliasso, F.; Savary, L.; Gallart-Ayala, H.; Ivanisevic, J.; Kawecki, T. J.
10.1101/2022.01.11.475896 — evolutionary biology — Posted on 2023-09-21
1675 An ATF4-centric regulatory network is required for the assembly and function of the OXPHOS system
Gagin, U.; Gomez, M. J.; Casajus-Pelegay, E.; Nieto-Arellano, R.; Arias-Sanroman, D.; Movilla, N.; Moreno-Loshuertos, R.; Sanchez-Cabo, F.; Enriquez, J. A.
10.1101/2023.09.21.558853 — molecular biology — Posted on 2023-09-21
1676 Influence of FTDP-17 mutants on circTau RNAs
Margvelani, G.; Welden, J. R.; Arizaca Maquera, K. A.; Miranda Sardon, S.; Stamm, S.
10.1101/2023.09.08.556913 — molecular biology — Posted on 2023-09-21
1677 A paradigm for regulation at the effector interface with RNA-binding proteins
Shah, K.; He, S.; Turner, D. J.; Corbo, J.; Rebbani, K.; Bateman, J.; Cheloufi, S.; Igreja, C.; Valkov, E.; Murn, J.
10.1101/2023.09.20.558714 — molecular biology — Posted on 2023-09-21
1679 Local endoreduplication of the host is a conserved process during Phytomyxea-host interaction
Hittorf, M.; Garvetto, A.; Magauer, M.; Kirchmair, M.; Salvenmoser, W.; Murua, P.; Neuhauser, S.
10.1101/2023.09.21.558765 — microbiology — Posted on 2023-09-21
1680 Molecular and phylogenetic characterization of the monkeypox outbreak in the South of Spain
Casimiro-Soriguer, C. S.; Perez-Florido, J.; Lara, M.; Camacho-Martinez, P.; Merino-Diaz, L.; Pupo-Ledo, I.; de Salazar, A.; Fuentes, A.; Vinuela, L.; Chueca, N.; Martinez-Martinez, L.; Lorusso, N.; Lepe, J. A.; Dopazo, J.; Garcia, F.
10.1101/2023.09.20.558741 — microbiology — Posted on 2023-09-21
1681 PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency
Crespo, R.; Ne, E.; Reinders, J.; Meier, J. I. J.; Li, C.; Jansen, S.; Gorska, A.; Kocer, S.; Kan, T. W.; Doff, W.; Dekkers, D.; Demmers, J.; Palstra, R. J.; Rao, S.; Mahmoudi, T.
10.1101/2023.09.21.558802 — microbiology — Posted on 2023-09-21
1683 DEAD box RNA helicases 5 and 17 are new host factors for Sindbis virus infection
Messmer, M.; Pierson, L.; Pasquier, C.; Djordjevic, N.; Chicher, J.; Hammann, P.; Pfeffer, S.; Girardi, E.
10.1101/2023.09.21.558232 — microbiology — Posted on 2023-09-21
1684 Bacteroides thetaiotaomicron metabolic activity decreases with polysaccharide molecular weight
Wong, J.; Chillier, N.; Fischer-Stettler, M.; Zeeman, S. C.; Battin, T. J.; Persat, A.
10.1101/2023.09.21.558885 — microbiology — Posted on 2023-09-21
1686 Theoretical Considerations and Empirical Predictions of the Pharmaco- and Population Dynamics of Heteroresistance
Levin, B. R. R.; Berryhill, B. A.; Gil-Gil, T.; Manuel, J. A.; Smith, A. P.; Choby, J. E.; Andersson, D. I.; Weiss, D. S.; Baquero, F.
10.1101/2023.09.21.558832 — microbiology — Posted on 2023-09-21
1688 Nested neural circuits generate distinct acoustic signals during Drosophila courtship
Lillvis, J. L.; Wang, K.; Shiozaki, H. M.; Xu, M.; Stern, D. L.; Dickson, B. J.
10.1101/2023.08.30.555537 — neuroscience — Posted on 2023-09-21
1690 Learning produces a hippocampal cognitive map in the form of an orthogonalized state machine
Sun, W.; Winnubst, J.; Natrajan, M.; Lai, C.; Kajikawa, K.; Michaelos, M.; Gattoni, R.; Stringer, C.; Flickinger, D.; Fitzgerald, J. E.; Spruston, N.
10.1101/2023.08.03.551900 — neuroscience — Posted on 2023-09-21
1697 Functional copy number variation in SQUALENE EPOXIDASE-LIKE genes affects photosystem II efficiency in Arabidopsis
Bezouw, R. v.; Nguyen, T.-P.; Hoang, N. V.; Vincenzi, E.; Velthoven, R. v.; Zhang, H.; Gao, Y.; Zhang, W.; Jacobi, R.; de Snoo, B. C.; Reyes Marquez, F.; Vasquez Catala, L.; Iqbal, M.; Jansen, S.; Mumm, R.; Harbinson, J.; Keurentjes, J. J. B.; Aarts, M. G. M.
10.1101/2023.09.21.558849 — plant biology — Posted on 2023-09-21
1698 Root Walker: an automated pipeline for large scale quantification of early root growth responses at high spatial and temporal resolution
Platre, M. P.; Mehta, P.; Halvorson, Z.; zhang, L.; Matias, G. F.; Brent, L.; Goulding, C.; Faizi, K.; Busch, W.
10.1101/2022.11.16.516796 — plant biology — Posted on 2023-09-21
1699 Thymidylate synthase disruption to limit cell proliferation in cell therapies
Sartori-Maldonado, R.; Montaser, H.; Soppa, I.; Eurola, S.; Balaz, M.; Puttonen, H.; Otonkoski, T.; Saarimaki-Vire, J.; Wartiovaara, K.
10.1101/2023.06.26.546441 — bioengineering — Posted on 2023-09-21
1701 Evolutionary dynamics of proteinaceous MAMPs reveals intrabacterial antagonism of plant immune perception
Stevens, D. M.; Moreno-Perez, A.; Weisberg, A. J.; Ramsing, C.; Fliegmann, J.; Zhang, N.; Madrigal, M.; Martin, G.; Steinbrenner, A.; Felix, G.; Coaker, G.
10.1101/2023.09.21.558511 — microbiology — Posted on 2023-09-21
1705 Syntaxin 6 delays prion protein fibril formation and prolongs presence of toxic aggregation intermediates
Sangar, D.; Hill, E.; Jack, K.; Batchelor, M.; Mistry, B.; Ribes, J. M.; Jackson, G. S.; Mead, S.; Bieschke, J.
10.1101/2022.08.25.505283 — biochemistry — Posted on 2023-09-21
1707 A conserved cell-pole determinant organizes proper polar flagellum formation
Arroyo-Perez, E. E.; Hook, J. C.; Alvarado, A.; Wimmi, S.; Glatter, T.; Thormann, K. M.; Ringgaard, S.
10.1101/2023.09.20.558563 — microbiology — Posted on 2023-09-21
1710 Recurrent circuits encode visual center-surround computations in themouse superior colliculus
Cui, P.; Song, K.; Mariatos Metaxas, D.; Isla, A. G.; Femenia, T.; Lazaridis, I.; Meletis, K.; Kumar, A.; Kardamakis, A. A.
10.1101/2023.09.03.556096 — neuroscience — Posted on 2023-09-21
1712 De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments
Eloff, K.; Kalogeropoulos, K.; Morell, O.; Mabona, A.; Berg Jespersen, J.; Williams, W.; van Beljouw, S. P. B.; Skwark, M.; Hougaard Laustsen, A.; Brouns, S. J. J.; Ljungars, A.; Schoof, E. M.; Van Goey, J.; auf dem Keller, U.; Beguir, K.; Lopez Carranza, N.; Jenkins, T. P.
10.1101/2023.08.30.555055 — bioinformatics — Posted on 2023-09-21
1713 CNC Knitting Micro-Resolution Mosquito Bite Blocking Textiles
Holt, B.; Oswalt, K.; England, A.; Murphy, R.; Owens, I.; Finney, M.; Wong, N.; Adhikari, S.; McCann, J.; Beckmann, J. F.
10.1101/2023.04.21.537869 — bioengineering — Posted on 2023-09-21
1715 Parvalbumin Interneuron Activity Underlies Vulnerability to Post-Traumatic Stress Disorder in Autism
Al Abed, A. S.; Allen, T. v.; Ahmed, N. Y.; Sellami, A.; Marighetto, A.; Desmedt, A.; Dehorter, N.
10.1101/2021.01.18.427217 — neuroscience — Posted on 2023-09-21
1716 Mesoscale molecular assembly is favored by the active, crowded cytoplasm
Shu, T.; Mitra, G.; Alberts, J. B.; Viana, M.; Levy, E. D.; Hocky, G. M.; Holt, L. J.
10.1101/2023.09.19.558334 — biophysics — Posted on 2023-09-21
1717 Diversity in the internal functional feeding elements of sympatric morphs of Arctic charr (Salvelinus alpinus)
Jonsdottir, G. O.; von Elm, L.-M.; Ingimarsson, F.; Tersigni, S.; Snorrason, S. S.; Palsson, A.; Steele, S. E.
10.1101/2023.02.17.528955 — evolutionary biology — Posted on 2023-09-21
1718 Steroidogenesis and androgen/estrogen signaling pathways are altered in in vitro matured testicular tissues of prepubertal mice
Moutard, L.; Goudin, C.; Jaeger, C.; Duparc, C.; Louiset, E.; Pereira, T.; Fraissinet, F.; Delessard, M.; Saulnier, J.; Rives-Feraille, A.; Delalande, C.; Lefebvre, H.; Rives, N.; Dumont, L.; Rondanino, C.
10.1101/2022.11.18.517042 — developmental biology — Posted on 2023-09-21
1719 Age-related STAT3 signaling regulates severity of respiratory syncytial viral infection in human bronchial epithelial cells
Zhao, C.; Wang, W.; Bai, Y.; Amonkar, G.; Mou, H.; Olejnik, J.; Hume, A. J.; Muhlberger, E.; Fang, Y.; Que, J.; Fearns, R.; Ai, X.; Lerou, P. H.
10.1101/2023.09.20.558606 — cell biology — Posted on 2023-09-21
1720 Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection
Armbruster, E.; Lee, J.; Hutchings, J.; VanderWal, A.; Enustun, E.; Adler, B.; Aindow, A.; Deep, A.; Rodriguez, Z.; Morgan, C.; Ghassemian, M.; Charles, E.; Cress, B.; Savage, D.; Doudna, J.; Pogliano, K.; Corbett, K.; Villa, E.; Pogliano, J.
10.1101/2023.09.20.558163 — cell biology — Posted on 2023-09-21
1721 Effect of alpha-tubulin acetylation on the doublet microtubule structure
Yang, S. K.; Kubo, S.; Black, C. S.; Peri, K.; Dai, D.; Valente-Paterno, M.; Gaertig, J.; Bui, K. H.
10.1101/2023.09.21.558788 — cell biology — Posted on 2023-09-21
1722 The Implant-Induced Foreign Body Response is Limited by CD13-Dependent Regulation of Ubiquitination of Fusogenic Proteins
Ghosh, M.; McGurk, F.; Norris, R.; Dong, A.; Nair, S.; Jellison, E.; Murphy, P. A.; Verma, R.; Shapiro, L. H.
10.1101/2023.09.20.558631 — cell biology — Posted on 2023-09-21
1725 Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis
Imoto, Y.; Xue, J.; Luo, L.; Raychaudhuri, S.; Itoh, K.; Craft, G. E.; Kwan, A. H.; Mackay, J.; Ha, T.; Watanabe, S.; Robinson, P. J.
10.1101/2023.09.21.558797 — cell biology — Posted on 2023-09-21
1726 Mitochondrial outer membrane integrity regulates a ubiquitin-dependent NF-κB inflammatory response
Vringer, E.; Riley, J.; Black, A.; Cloix, C.; Lilla, S.; Walczak, H.; Gyrd-Hansen, M.; Huang, D.; Zanivan, S.; Tait, S.
10.1101/2023.09.21.558776 — cell biology — Posted on 2023-09-21
1727 Cytogenetic resource enables mechanistic resolution of changing trends in human pluripotent stem cell aberrations linked to feeder-free culture
Stavish, D.; Price, C. J.; Gelezauskaite, G.; Leonhard, K. A.; Taapken, S. M.; McIntire, E. M.; Laing, O.; James, B. M.; Riley, J. J.; Zerbib, J.; Baker, D.; Harding, A. L.; Jestice, L. H.; Eleveld, T. F.; Gillis, A. J. M.; Hillenius, S.; Looijenga, L. H. J.; Gokhale, P. J.; Ben-David, U. J.; Ludwig, T.; Barbaric, I.
10.1101/2023.09.21.558777 — cell biology — Posted on 2023-09-21
1731 PubNavigator as an undergraduate teaching tool
Marroquin-Flores, R. A.; Campbell, M. A.; Grimes, S.; Limeri, L. B.
10.1101/2023.09.18.558293 — scientific communication and education — Posted on 2023-09-21
1732 Mapping Cell-to-cell Interactions from Spatially Resolved Transcriptomics Data
Zhu, J. Z.; Wang, Y.; Chang, W. Y.; Malewska, A.; Napolitano, F.; Gahan, J. C.; Unni, N.; Zhao, M.; Wu, F.; Guo, L.; Zhao, Z.; Chen, D. Z.; Hannan, R.; Zhang, S.; Xiao, G.; Mu, P.; Hanker, A. B.; Strand, D.; Arteaga, C. L.; Desai, N.; Wang, X.; Xie, Y.; Wang, T.
10.1101/2023.09.18.558298 — bioinformatics — Posted on 2023-09-21
1733 Simple ways to avoid collecting highly 137Cs-contaminated Aralia elata buds
Sakai, M.; Watanabe, M.; Kanao Koshikawa, M.; Tanaka, A.; Takahashi, A.; Takechi, S.; Takagi, M.; Tsuji, T.; Tsuji, H.; Takeda, T.; Jo, J.; Tamaoki, M.; Hayashi, S.
10.1101/2023.09.18.558164 — ecology — Posted on 2023-09-21
1737 An RGB based deep neural network for high fidelity Fusarium head blight phenotyping in wheat
Cooper, J.; Du, C.; Beaver, Z.; Zheng, M.; Page, R.; Wodarek, J. R.; Matny, O.; Szinyei, T.; Quinones, A.; Anderson, J. A.; Smith, K. P.; Yang, C.; Steffenson, B. J.; Hirsch, C. D.
10.1101/2023.09.20.558703 — plant biology — Posted on 2023-09-21
1740 Structural insights into the complex of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Tariq, M.; Ikeya, T.; Togashi, N.; Fairall, L.; Kamei, S.; Mayooramurugan, S.; Abbott, L. R.; Hasan, A.; Bueno-Alejo, C.; Sukegawa, S.; Romartinez-Alonso, B.; Muro Campillo, M. A.; Hudson, A. J.; Ito, Y.; Schwabe, J. W.; Dominguez, C.; Tanaka, K.
10.1101/2022.10.10.511529 — biochemistry — Posted on 2023-09-21
1743 Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus
Burmeister, W. P.; Boutin, L.; Balestra, A. C.; Gröger, H.; Ballandras-Colas, A.; Hutin, S.; Kraft, C.; Grimm, C.; Böttcher, B.; Fischer, U.; Tarbouriech, N.; Iseni, F.
10.1101/2023.09.03.556150 — molecular biology — Posted on 2023-09-21
1745 Diversity and ecological functions of viruses inhabiting the oil reservoirs
An, L.; Liu, X.; Wang, J.; Xu, J.; Chen, X.; Liu, X.; Hu, B.; Nie, Y.; Wu, X.
10.1101/2023.09.19.558540 — microbiology — Posted on 2023-09-21
1746 Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets
Sibener, L. J.; Mosberger, A. C.; Chen, T. X.; Athalye, V. R.; Murray, J. M.; Costa, R. M.
10.1101/2023.09.20.558560 — neuroscience — Posted on 2023-09-21
1747 Immune activation state modulates retrieval of infant engrams
Power, S. D.; Stewart, E.; Zielke, L.; Byrne, E. P.; Douglas, A.; Ortega-de San Luis, C.; Lynch, L.; Ryan, T. J.
10.1101/2022.04.24.488172 — neuroscience — Posted on 2023-09-21
1749 Comparative single-cell regulome reveals evolutionary innovations in neural progenitor cells during primate corticogenesis
Liu, Y.; Luo, X.; Sun, Y.; Chen, K.; Hu, T.; You, B.; Xu, J.; Zhang, F.; Meng, X.; Li, X.; He, X.; Li, C.; Su, B.
10.1101/2023.09.20.558575 — evolutionary biology — Posted on 2023-09-21
1752 Micro-Scale Control of Oligodendrocyte Morphology and Myelination by the Intellectual Disability-Linked Protein Acyltransferase ZDHHC9
Jeong, H.-K.; Gonzalez-Fernandez, E.; Crawley, I.; Hwang, J.; Martin, D. D. O.; Bamji, S. X.; KIM, J.-I.; Kang, S.-H.; Thomas, G.
10.1101/2023.09.19.558291 — neuroscience — Posted on 2023-09-21
1754 Serotonin predictively encodes value
Harkin, E. F.; Grossman, C. D.; Cohen, J. Y.; Beïque, J.-C.; Naud, R.
10.1101/2023.09.19.558526 — neuroscience — Posted on 2023-09-21
1757 Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
Mich, J. K.; Sunil, S.; Johansen, N.; Martinez, R. A.; Leytze, M.; Gore, B. B.; Mahoney, J. T.; Ben-Simon, Y.; Bishaw, Y.; Brouner, K.; Campos, J.; Canfield, R.; Casper, T.; Dee, N.; Egdorf, T.; Gary, A.; Gibson, S.; Goldy, J.; Groce, E. L.; Hirschstein, D.; Loftus, L.; Lusk, N.; Malone, J.; Martin, N. X.; Monet, D.; Omstead, V.; Opitz-Araya, X.; Oster, A.; Alice Pom, C.; Potekhina, L.; Reding, M.; Rimorin, C.; Ruiz, A.; Sedeno-Cortes, A. E.; Shapovalova, N. V.; Taormina, M.; Taskin, N.; Tieu, M.; Valera Cuevas, N. J.; Weed, N.; Way, S. W.; Yao, Z.; McMillen, D. A.; Kunst, M.; McGraw, M.; Thya
10.1101/2023.09.20.558718 — neuroscience — Posted on 2023-09-21
1758 Computational analysis of long-range allosteric communications in CFTR
Ersoy, A.; Altintel, B.; Livnat-Levanon, N.; Ben-Tal, N.; Haliloglu, T.; Lewinson, O.
10.1101/2023.06.07.543997 — biophysics — Posted on 2023-09-21
1761 Alternate splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and cell fate in ovarian cancer.
Javed, Z.; Shin, D. H.; Pan, W.; White, S. R.; Kim, Y. S.; Elhaw, A. T.; Kamlapurkar, S.; Cheng, Y.-Y.; Benson, J. C.; Abdelnaby, A. E.; Phaeton, R.; Wang, H.-G.; Yang, S.; Sullivan, M. L. G.; Watkins, S. C.; Mullett, S. J.; Gelhaus, S. L.; Lee, N. Y.; Coffman, L.; Aird, K. M.; Trebak, M.; Karthikeyan, M.; Walter, V.; Hempel, N.
10.1101/2023.09.20.558501 — cancer biology — Posted on 2023-09-20
1764 600+ insect genomes reveal repetitive element dynamics and highlight biodiversity-scale repeat annotation challenges
Sproul, J. S.; Hotaling, S.; Heckenhauer, J.; Powell, A.; Marshall, D.; Larracuente, A. M.; Kelley, J. L.; Pauls, S. U.; Frandsen, P. B.
10.1101/2022.06.02.494618 — genomics — Posted on 2023-09-20
1765 Epigenetic fidelity in complex biological systems and implications for ageing
Duffield, T.; Csuka, L.; Akalan, A.; Vega Magdaleno, G.; Senez, L.; Palmer, D.; de Magalhaes, J. P.
10.1101/2023.04.29.538716 — genomics — Posted on 2023-09-20
1766 Genomic consequences of isolation and inbreeding in an island dingo population
Leon-Apodaca, A. V.; Kumar, M.; del Castillo, A.; Conroy, G. C.; Lamont, R. W.; Ogbourne, S.; Cairns, K. M.; Borburgh, L.; Behrendorff, L.; Subramanian, S.; Szpiech, Z. A.
10.1101/2023.09.15.557950 — evolutionary biology — Posted on 2023-09-20
1767 Severe fire regimes decrease ectothermic populations' resilience
Sousa, H. C.; Malvasio, A.; Colli, G. R.; Salguero-Gomez, R. C.
10.1101/2023.06.25.546448 — ecology — Posted on 2023-09-20
1768 Hexokinase 1 forms rings that constrict mitochondria during energy stress
Pilic, J.; Gottschalk, B.; Bourgeois, B.; Habisch, H.; Koshenov, Z.; Oflaz, F. E.; Erdogan, Y. C.; Shoshan-Barmatz, V.; Madl, T.; Graier, W. F.; Malli, R.
10.1101/2023.03.20.533440 — cell biology — Posted on 2023-09-20
1769 Single-step genome engineering in the bee gut symbiont Snodgrassella alvi
Lariviere, P. J.; Ashraf, A. H. M. Z.; Leonard, S. P.; Miller, L. G.; Moran, N. A.; Barrick, J. E.
10.1101/2023.09.19.558440 — microbiology — Posted on 2023-09-20
1770 Antiviral Wolbachia strains associate with Aedes aegypti endoplasmic reticulum membranes and disturb host cell lipid distribution to restrict dengue virus replication.
Kriiger-Loterio, R.; Monson, E.; Templin, R.; Bruyne, J. T.; Flores, H. A.; Mackenzie, J.; Ramm, G.; Helbig, K.; Simmons, C. P.; Fraser, J. E.
10.1101/2023.09.14.557745 — microbiology — Posted on 2023-09-20
1771 Single nuclei RNAseq stratifies multiple sclerosis patients into distinct white matter glia responses
Macnair, W.; Calini, D.; Agirre, E.; Bryois, J.; Jaekel, S.; Kukanja, P.; Stokar-Regenscheit, N.; Ott, V.; Foo, L. C.; Collin, L.; Schippling, S.; Urich, E.; Nutma, E.; Marzin, M.; Amor, S.; Magliozzi, R.; Heidari, E.; Robinson, M. D.; ffrench-Constant, C.; Castelo-Branco, G.; Williams, A.; Malhotra, D.
10.1101/2022.04.06.487263 — neuroscience — Posted on 2023-09-20
1779 Structure of RADX and mechanism for regulation of RAD51 nucleofilaments
Balakrishnan, S.; Adolph, M.; Tsai, M.-s.; Gallagher, K.; Cortez, D.; Chazin, W. J.
10.1101/2023.09.19.558089 — biophysics — Posted on 2023-09-20
1781 A novel bivalent interaction mode underlies a non-catalytic mechanism for Pin1-mediated Protein Kinase C regulation
Chen, X.-R.; Dixit, K.; Yang, Y.; McDermott, M. I.; Imam, H. T.; Bankaitis, V. A.; Igumenova, T. I.
10.1101/2023.09.18.558341 — biophysics — Posted on 2023-09-20
1782 ACE2-Coated Virus-Like Particles Effectively Block SARS-CoV-2 Infection
Bayraktar, C.; Kayabolen, A.; Odabas, A.; Durgun, A.; Kok, I.; Sevinc, K.; Supramaniam, A.; Idris, A.; Bagci-Onder, T.
10.1101/2023.09.19.558424 — bioengineering — Posted on 2023-09-20
1787 G4-Ligand Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures
Berner, A.; Das, R. N.; Bhuma, N.; Golebiewska, J.; Abrahamsson, A.; Andreasson, M.; Chaudhari, N.; Doimo, M.; Bose, P. P.; Chand, K.; Stromberg, R.; Wanrooij, S.; Chorell, E.
10.1101/2023.09.20.558437 — biochemistry — Posted on 2023-09-20
1788 Structure and dynamics of a pentameric KCTD5/Cullin3/Gβγ E3 ubiquitin ligase complex
Nguyen, D. M.; Rath, D. H.; Devost, D.; Petrain, D.; Rizk, R.; Ji, A. X.; Narayanan, N.; Yong, D.; Zhai, A.; Kuntz, D. A.; Mian, M. U. Q.; Pomroy, N. C.; Keszei, A. F. A.; Benlekbir, S.; Mazhab-Jafari, M. T.; Rubinstein, J. L.; Hebert, T. E.; Prive, G. G.
10.1101/2023.09.20.558662 — biochemistry — Posted on 2023-09-20
1791 Model-directed generation of CRISPR-Cas13a guide RNAs designs artificial sequences that improve nucleic acid detection
Mantena, S.; Pillai, P. P.; Petros, B. A.; Welch, N. L.; Myhrvold, C.; Sabeti, P. C.; Metsky, H. C.
10.1101/2023.09.20.557569 — genomics — Posted on 2023-09-20
1792 Choclo virus (CHOV) recovered from deep metatranscriptomics of archived museum tissues
Salazar-Hamm, P. S.; Johnson, W. L.; Nofchissey, R.; Salazar, J. R.; Gonzalez, P.; Dunnum, J. L.; Armien, B.; Cook, J. A.; Domman, D. B.; Dinwiddie, D. L.
10.1101/2023.09.19.558559 — genomics — Posted on 2023-09-20
1794 Larval thermosensitivity shapes adult population dynamics in Anopheles mosquitoes
Estupinan, J.; Weyrich, A. M.; Schloesser, P.; Naujoks, C.; Gildenhard, M.; Diarra, A.; Diallo, M.; Sangare, D.; Telschow, A.; Hsieh, C.-h.; Levashina, E. A.; Carrillo-Bustamante, P.
10.1101/2023.09.19.558414 — ecology — Posted on 2023-09-20
1797 Bacterial Efflux Pump Modulators Prevent Bacterial Growth in Macrophages and Under Broth Conditions that Mimic the Host Environment
Allgood, S. C.; Su, C.-C.; Crooks, A. L.; Meyer, C. T.; Zhou, B.; Betterton, M. D.; Barbachyn, M. R.; Yu, E. W.; Detweiler, C. S.
10.1101/2023.09.20.558466 — microbiology — Posted on 2023-09-20
1799 Mpox virus spreads from cell-to-cell and leads to neuronal injury in human cerebral organoids
Schultz-Pernice, I.; Fahmi, A.; Chiu, Y.-C.; Oliveira Esteves, B. I.; David, T.; Golomingi, A.; Zumkehr, B.; Jandrasits, D.; Zuest, R.; Steiner, S.; Wotzkow, C.; Blank, F.; Engler, O. B.; Baud, D.; Alves, M. P.
10.1101/2023.09.19.558432 — microbiology — Posted on 2023-09-20
1800 Diversity and distribution of viruses inhabiting the oil reservoirs
An, L.; Liu, X.; Wang, J.; Xu, J.; Chen, X.; Liu, X.; Hu, B.; Nie, Y.; Wu, X.
10.1101/2023.09.19.558540 — microbiology — Posted on 2023-09-20
1802 Enhanced ISGylation reduces respiratory distress following Francisella novicida infection
Upton, E. M.; Luhmann, E. K.; Zhang, Y.; Ripley, B. M.; Meyerholz, D. K.; Radoshevich, L.
10.1101/2023.09.19.558558 — microbiology — Posted on 2023-09-20
1803 Domestic dogs in indigenous Amazonian communities: key players in Leptospira cycling and transmission?
Guzman, D. A.; Diaz, E.; Saenz, C.; Alvarez, H.; Cueva, R.; Zapata-Rios, G.; Prado-Vivar, B.; Falconi, M.; Pearson, T.; Barragan, V.
10.1101/2023.09.19.558554 — microbiology — Posted on 2023-09-20
1804 A conserved cell-pole determinant organizes proper polar flagellum formation
Arroyo-Perez, E. E.; Hook, J. C.; Alvarado, A.; Wimmi, S.; Glatter, T.; Thormann, K. M.; Ringgaard, S.
10.1101/2023.09.20.558563 — microbiology — Posted on 2023-09-20
1805 Characteristics and functions of infection-enhancing antibodies to the N-terminal domain of SARS-CoV-2
Connor, R. I.; Sakharkar, M. I.; Rappazzo, C. G.; Kaku, C. I.; Curtis, N. C.; Shin, S.; Wieland-Alter, W. F.; Weiner, J. A.; Ackerman, M. E.; Walker, L. M.; Lee, J.; Wright, P. F.
10.1101/2023.09.19.558444 — immunology — Posted on 2023-09-20
1806 Immunogenicity and Efficacy of TNX-1800, A Live Virus Recombinant Poxvirus Vaccine Candidate, Against SARS-CoV-2 Challenge in Nonhuman Primates
Awasthi, M.; Macaluso, A.; Myscofski, D.; Prigge, J.; Koide, F.; Noyce, R. S.; Fogarty, S.; Stillwell, H.; Goebel, S. J.; Daugherty, B.; Nasar, F.; Bavari, S.; Lederman, S.
10.1101/2023.09.19.558485 — immunology — Posted on 2023-09-20
1811 Prolonged survival of rabid mice after treatment with Poly-ICLC Hiltonol (R)
Brandao, P. E.; Agostinho, W. C.; Caballero, O.; Salazar, A. M.; Gomes, C. O. M. S.
10.1101/2023.09.18.558218 — pharmacology and toxicology — Posted on 2023-09-20
1812 Patient-Derived Medullary Thyroid Cancer Organoids; a Model for Patient-tailored Drug and PET-Tracer Screening
Sondorp, L. H. J.; Jager, E. C.; Farinha Antunes, I.; Maturi, R.; Jansen, L.; Zandee, W. T.; Brouwers, A. H.; Links, T. P.; Coppes, R. P.; Kruijff, S.
10.1101/2023.09.18.558266 — cancer biology — Posted on 2023-09-20
1816 The genomics and evolution of inter-sexual mimicry and female-limited polymorphisms in damselflies
Willink, B.; Tunström, K.; Nilen, S.; Chikhi, R.; Lemane, T.; Takahashi, M.; Takahashi, Y.; Svensson, E. I.; Wheat, C. W.
10.1101/2023.03.27.532508 — evolutionary biology — Posted on 2023-09-20
1818 Loss of NMDA receptor function during development results in decreased KCC2 expression and increased neurons in the zebrafish forebrain.
Napoli, A. J.; Laderwager, S.; Zoodsma, J. D.; Biju, B.; Mucollari, O.; Schubel, S. K.; Aprea, C.; Sayed, A.; Morgan, K.; Napoli, A.; Flanagan, S.; Wollmuth, L.; Sirotkin, H. I.
10.1101/2023.08.25.554812 — neuroscience — Posted on 2023-09-20
1822 Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse
Kurt, Z.; Cheng, J.; McQuillen, C. N.; Saleem, Z.; Hsu, N.; Jiang, N.; Barrere-Cain, R.; Pan, C.; Franzen, O.; Koplev, S.; Wang, S.; Bjorkegren, J.; Lusis, A. J.; Blencowe, M.; Yang, X.
10.1101/2023.06.08.544148 — systems biology — Posted on 2023-09-20
1825 Natural disaster alters the adaptive benefits of sociality
Testard, C.; Shergold, C.; Acevedo-Ithier, A.; Hart, J.; Negron-Del Valle, J.; Philips, D.; Watowich, M.; Sanguinetti-Scheck, J. I.; Montague, M.; Snyder-Mackler, N. J.; Higham, J.; Platt, M.; Brent, L. J.
10.1101/2023.07.17.549328 — animal behavior and cognition — Posted on 2023-09-20
1827 TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling.
Xiong, L.; Zhevlakova, I.; West, X. Z.; Gao, D.; Murtazina, R.; Horak, A.; Brown, J. M.; Molokotina, I.; Podrez, E. A.; Byzova, T. V.
10.1101/2023.08.14.553236 — immunology — Posted on 2023-09-20
1829 Lateral Septal Circuits Govern Schizophrenia-Like Effects of Ketamine on Social Behavior
Wang, R.; Peterson, Z. J.; Balasubramanian, N.; Khan, K. M.; Chimenti, M. S.; Thedens, D.; Nickl-Jockschat, T.; Marcinkiewcz, C.
10.1101/2023.08.08.552372 — neuroscience — Posted on 2023-09-20
1830 General and specific patterns of cortical gene expression as substrates of complex cognitive functioning
Moodie, J. E.; Harris, S. E.; Harris, M. A.; Buchanan, C. R.; Davies, G.; Taylor, A.; Redmond, P.; Liewald, D.; Valdes Hernandez, M. D.; Shenkin, S. D.; Russ, T. C.; Munoz Maniega, S. C.; Luciano, M.; Corley, J.; Stolicyn, A.; Shen, X.; Steele, D.; Waiter, G.; Sandu-Giuraniuc, A.; Bastin, M.; Wardlaw, J.; McIntosh, A. M.; Whalley, H. C.; Tucker-Drob, E. M.; Deary, I.; Cox, S. R.
10.1101/2023.03.16.532915 — neuroscience — Posted on 2023-09-20
1831 Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure
Ishigohoka, J.; Bascon-Cardozo, K.; Bours, A.; Fuss, J.; Rhie, A.; Mountcastle, J.; Haase, B.; Chow, W.; Collins, J.; Howe, K.; Uliano-Silva, M.; Fedrigo, O.; Jarvis, E. D.; Perez-Tris, J.; Illera, J. C.; Liedvogel, M.
10.1101/2021.12.22.473882 — evolutionary biology — Posted on 2023-09-20
1835 CRONOSOJA: a daily time-step hierarchical model predicting soybean development across maturity groups in the Southern Cone
Severini, A. D.; Alvarez-Prado, S.; Otegui, M. E.; Kavanova, M.; Vega, C.; Zuil, S.; Ceretta, S.; Acreche, M. M.; Amarilla, F.; Cicchino, M. A.; Fernandez Long, M. E.; Crespo, A. O.; Serrago, R.; Miralles, D. J.
10.1101/2023.09.18.558336 — plant biology — Posted on 2023-09-20
1837 PURA Syndrome-causing mutations impair PUR-domain integrity and affect P-body association
Proske, M.; Janowski, R.; Bacher, S.; Kang, H.-S.; Monecke, T.; Koehler, T.; Hutten, S.; Tretter, J.; Crois, A.; Molitor, L.; Varela-Rial, A.; Fino, R.; Donati, E.; De Fabritiis, G.; Dormann, D.; Sattler, M.; Niessing, D.
10.1101/2023.09.19.558386 — molecular biology — Posted on 2023-09-20
1838 A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model
Latif-Hernandez, A.; Yang, T.; Raymond-Butler, R.; Moran-Losada, P.; Minhas, P.; White, H.; Tran, K. C.; Liu, H.; Simmons, D.; Langness, V.; Andreasson, K.; Wyss-Coray, T.; Longo, F. M.
10.1101/2023.09.18.558138 — neuroscience — Posted on 2023-09-20
1839 Plant-based production of diverse human milk oligosaccharides
Barnum, C. R.; Paviani, B.; Couture, G.; Masarweh, C.; Chen, Y.; Huang, Y.-P.; Mills, D. A.; Lebrilla, C. B.; Barile, D.; Yang, M.; Shih, P.
10.1101/2023.09.18.558286 — plant biology — Posted on 2023-09-20
1840 High-resolution mapping of Ryd4Hb, a major resistance gene to Barley yellow dwarf virus from Hordeum bulbosum
Pidon, H.; Ruge-Wehling, B.; Will, T.; Habekuss, A.; Wendler, N.; Oldach, K.; Maasberg-Prelle, A.; Korzun, V.; Stein, N.
10.1101/2023.09.19.558385 — plant biology — Posted on 2023-09-20
1841 Near-infrared imaging of phytochrome-derived autofluorescence in plant nuclei
Yoshinari, A.; Isoda, R.; Yagi, N.; Sato, Y.; Lindeboom, J. J.; Ehrhardt, D. W.; Frommer, W. B.; Nakamura, M.
10.1101/2023.09.18.558255 — plant biology — Posted on 2023-09-20
1842 The Arabidopsis U1 snRNP regulates mRNA 3'-end processing
Mangilet, A. F.; Weber, J.; Schueler, S.; Droste-Borel, I.; Streicher, S.; Schmutzer, T.; Rot, G.; Macek, B.; Laubinger, S.
10.1101/2023.09.19.558503 — plant biology — Posted on 2023-09-20
1845 Autoinhibited kinesin-1 adopts a hierarchical folding pattern
Tan, Z.; Yue, Y.; da Veiga Leprevost, F.; Haynes, S. E.; Basrur, V.; Nesvizhskii, A. I.; Verhey, K. J.; Cianfrocco, M. A.
10.1101/2023.01.26.525761 — biophysics — Posted on 2023-09-20
1847 Single cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers
Kabeer, F.; Tran, H.; Andronescu, M.; Singh, G.; Lee, H.; Salehi, S.; Biele, J.; Brimhall, J.; Gee, D.; Cerda, V.; O Flanagan, C. H.; Algara, T.; Kono, T.; Lai, D.; Zaikova, E.; Beatty, S.; Lee, E.; Moore, R. A.; Mungall, A. J.; IMAXT Consortium, ; Williams, M.; Roth, A.; Campbell, K. R.; Shah, S. P.; Aparicio, S.
10.1101/2023.09.19.558329 — genomics — Posted on 2023-09-20
1849 Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates
Chocarro, J.; Rico, A. J.; Ariznabarreta, G.; Roda, E.; Honrubia, A.; Collantes, M.; Penuelas, I.; Vazquez, A.; Rodriguez-Perez, A. I.; Labandeira-Garcia, J. L.; Vila Bover, M.; Lanciego, J. L.
10.1101/2023.08.04.551615 — neuroscience — Posted on 2023-09-20
1851 PDB ProtVista: A reusable and open-source sequence feature viewer
Deshpande, M.; Varadi, M.; Paysan-Lafosse, T.; Nair, S.; Piovesan, D.; Mir, S.; Gutmanas, A.; Tosatto, S. C. E.; Velankar, S.
10.1101/2022.07.22.500790 — bioinformatics — Posted on 2023-09-20
1853 Thalamic regulation of ocular dominance plasticity in adult visual cortex
Qin, Y.; Ahmadlou, M.; Suhai, S.; Neering, P.; de Kraker, L.; Heimel, J. A.; Levelt, C. N.
10.1101/2023.03.23.533941 — neuroscience — Posted on 2023-09-20
1855 Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles
Jacobsen Skanderup, A.; Zhu, G.; Rahman, C.; Getty, V.; Baruah, P.; Carrie, H.; Lim, A.; Guo, Y. A.; Poh, Z.; Sim, N.; Abdelmoneim, A.; Cai, Y.; Ho, D.; Thangaraju, S.; Poon, P.; Lau, Y.; Gan, A.; Ng, S.; Odinokov, D.; Koo, S.-L.; Chong, D.; Tay, B.; Tan, T.; Yap, Y.; Chok, A.; Ng, M.; Tan, P.; Tan, D.; Wong, L.; Wong, P.; Tan, I.
10.1101/2023.07.28.550922 — bioinformatics — Posted on 2023-09-20
1858 Glycosylation-modified antigens as an inverse vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
Cao, S.; Maulloo, C. D.; Raczy, M. M.; Sabados, M.; Slezak, A. J.; Nguyen, M.; Solanki, A.; Wallace, R. P.; Shim, H.-N.; Wilson, D. S.; Hubbell, J. A.
10.1101/2023.03.23.534004 — bioengineering — Posted on 2023-09-20
1861 Coupling of 12 chromosomal inversions maintains a strong barrier to gene flow between ecotypes
Le Moan, A.; Stankowski, S.; Rafajlovic, M.; Martinez Ortega, O.; Faria, R.; Butlin, R.; Johannesson, K.
10.1101/2023.09.18.558209 — evolutionary biology — Posted on 2023-09-20
1863 Identification of multiple transcription factor genes potentially involved in the development of electrosensory versus mechanosensory lateral line organs
Minarik, M.; Modrell, M. S.; Gillis, J. A.; Campbell, A. S.; Fuller, I.; Lyne, R.; Micklem, G.; Gela, D.; Psenicka, M.; Baker, C. V. H.
10.1101/2023.04.14.536701 — developmental biology — Posted on 2023-09-20
1865 Implications of the three-dimensional chromatin organization for genome evolution in a fungal plant pathogen
Torres, D.; Kramer, M.; Tracanna, V.; Lorencini Fiorin, G.; Cook, D.; Seidl, M. F.; Thomma, B.
10.1101/2023.04.04.535574 — microbiology — Posted on 2023-09-19
1867 Designed Endocytosis-Triggering Proteins mediate Targeted Degradation and amplify signaling
Huang, B.; Abedi, M.; Ahn, G.; Coventry, B.; Sappington, I.; Wang, R.; Schlichthaerle, T.; Zhang, J. Z.; Wang, Y.; Goreshnik, I.; Chiu, C. W.; Chazin-Gray, A.; Chan, S.; Gerben, S.; Murray, A.; Wang, S.; O'Neill, J.; Yeh, R.; Misquith, A.; Wolf, A.; Tomasovic, L. M.; Piraner, D. I.; Gonzalez, M. J. D.; Bennett, N. R.; Venkatesh, P.; Satoe, D.; Ahlrichs, M.; Dobbins, C.; Yang, W.; Wang, X.; Vafeados, D.; Mout, R.; Shivaei, S.; Cao, L.; Carter, L.; Stewart, L.; Spangler, J. B.; Bernardes, G. J. L.; Roybal, K. T.; Greisen, P.; Li, X.; Bertozzi, C.; Baker, D.
10.1101/2023.08.19.553321 — synthetic biology — Posted on 2023-09-20
1870 Anaerobic arsenic methylation as a microbial warfare strategy
Qiao, J.; Sallet, H.; Meibom, K. L.; Jacquemin, N.; Bernier-Latmani, R.
10.1101/2023.01.09.523296 — microbiology — Posted on 2023-09-19
1873 Coding of time with non-linear mixed selectivity in Prefrontal Cortex ensembles
Mikkelsen, C.; Charczynski, S. J.; Warden, M. R.; Miller, E. K.; Howard, M.
10.1101/2023.04.07.535754 — neuroscience — Posted on 2023-09-19
1874 Tumor-immune metaphenotypes orchestrate an evolutionary bottleneck that promotes metabolic transformation
West, J.; Rentzeperis, F.; Adam, C.; Bravo, R.; Luddy, K. A.; Robertson-Tessi, M.; Anderson, A. R. A.
10.1101/2022.06.03.493752 — cancer biology — Posted on 2023-09-19
1876 Reference genome choice and filtering thresholds jointly influence phylogenomic analyses
Rick, J. A.; Brock, C. D.; Lewanski, A. L.; Golcher-Benavides, J.; Wagner, C. E.
10.1101/2022.03.10.483737 — bioinformatics — Posted on 2023-09-19
1878 Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics
Wallace, R. P.; Refvik, K. C.; Antane, J. T.; Brünggel, K.; Tremain, A. C.; Raczy, M. R.; Alpar, A. T.; Nguyen, M.; Solanki, A.; Slezak, A. J.; Watkins, E. A.; Lauterbach, A. L.; Wilson, D. S.; Hubbell, J. A.
10.1101/2023.04.07.534593 — bioengineering — Posted on 2023-09-19
1880 Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription
Mahat, D. B.; Tippens, N. D.; Martin-Rufino, J. D.; Waterton, S. K.; Fu, J.; Blatt, S. E.; Sharp, P. A.
10.1101/2023.09.15.558015 — genomics — Posted on 2023-09-19
1881 Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice
Bashkirova, E.; Klimpert, N.; Monahan, K.; Campbell, C.; Osinski, J.; Tan, L.; Schieren, I.; Pourmorady, A.; Stecky, R.; Barnea, G.; Xie, X. S.; Abdus-Saboor, I.; Shykind, B.; Marlin, B. J.; Gronostajski, R.; Fleischmann, A.; Lomvardas, S.
10.1101/2023.03.15.532726 — genomics — Posted on 2023-09-19
1883 Genomic context sensitizes regulatory elements to genetic disruption
Ordonez, R.; Zhang, W.; Ellis, G.; Zhu, Y.; Ashe, H. J.; Ribeiro-dos-Santos, A. M.; Brosh, R.; Huang, E.; Hogan, M. S.; Boeke, J. D.; Maurano, M. T.
10.1101/2023.07.02.547201 — genomics — Posted on 2023-09-19
1884 The Atlantic Forest of South America: spatiotemporal dynamics of remaining vegetation and implications for conservation
Vancine, M. H.; Muylaert, R. L.; Niebuhr, B. B.; Oshima, J. E. d. F.; Tonetti, V.; Bernardo, R.; De Angelo, C.; Rosa, M. R.; Grohmann, C. H.; Ribeiro, M. C.
10.1101/2023.09.16.558076 — ecology — Posted on 2023-09-19
1885 Alzheimer's Disease associations of ferritin and glutathione with oxidative damage and neuronal loss
Thorwald, M.; Godoy-Lugo, J. A.; Silva, J.; Head, E.; O'Day, P. A.; Morgan, T. E.; Forman, H. J.; Finch, C. E.
10.1101/2023.03.28.534324 — neuroscience — Posted on 2023-09-19
1888 Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer's disease
Pierson, S.; Fiock, K.; Wang, R.; Balasubramanian, N.; Reinhardt, J.; Khan, K.; James, T. D.; Betters, R.; Deniz, K.; Lee, G.; Aldridge, G.; Hefti, M. M.; Marcinkiewcz, C. A.
10.1101/2022.11.22.517403 — neuroscience — Posted on 2023-09-19
1890 The prophylactic value of TNF-alpha inhibitors against retinal cell apoptosis and optic nerve axon loss after corneal surgery or trauma
Paschalis, E. I.; Zhou, C.; Sharma, J.; Dohlman, T. H.; Kim, S.; Lei, F.; Chodosh, J.; Vavvas, D.; Urtti, A.; Papaliodis, G.; Dohlman, C. H.
10.1101/2022.10.06.510713 — pathology — Posted on 2023-09-19
1891 Leveraging the p53 signaling pathway as a radio-sensitization strategy in endometrial cancer
Vargas, R.; Petty, A.; Durmaz, A.; Lin-Rahardja, K.; Reizes, O.; Debernardo, R.; Scott, J.
10.1101/2022.09.06.505009 — cancer biology — Posted on 2023-09-19
1892 Single-cell analysis characterizes PLK1 as a catalyst of an immunosuppressive tumor microenvironment in LUAD
Kong, Y.; Li, C.; Liu, J.; Zhang, M.; Allison, D. B.; Hassan, F.; He, D.; Wang, X.; Mao, F.; Zhang, Q.; Zhang, Y.; Li, Z.; Wu, S.; Wang, C.; Liu, X.
10.1101/2023.08.02.551692 — cancer biology — Posted on 2023-09-19
1893 Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states
Lin, D. Y.-w.; Kueffer, L. E.; Juneja, P.; Wales, T. E.; Engen, J. R.; Andreotti, A. H.
10.1101/2023.06.02.543453 — biophysics — Posted on 2023-09-19
1894 DNA Tetrahedral Nanocages as a Promising Nanocarrier for Dopamine Delivery in Neurological Disorders
Singh, R.; Kansara, K.; Mandal, S.; Varshney, R.; Gupta, S.; Kumar, A.; Maiti, P. K.; Bhatia, D. D.
10.1101/2023.09.19.558434 — bioengineering — Posted on 2023-09-19
1895 Magnetogenetic cell activation using endogenous ferritin
Pomeranz, L. E.; Li, R.; Yu, X. A.; Kelly, L.; Hassanzadeh, G.; Molina, H.; Gross, D.; Brier, M. I.; Vaisey, G.; Wang, P.; Jimenez-Gonzalez, M.; Garcia-Ocana, A.; Dordick, J.; Friedman, J. M.; Stanley, S. A.
10.1101/2023.06.20.545120 — bioengineering — Posted on 2023-09-19
1897 At the core of salinity: divergent transcriptomic responses to neutral and alkaline salinity in Arabidopsis thaliana
Almira-Casellas, M. J.; Busoms, S.; Perez-Martin, L.; Escola, G.; Lopez-Valinas, A.; Garcia-Molina, A.; Llugany, M.; Poschenrieder, C.
10.1101/2023.02.05.527167 — molecular biology — Posted on 2023-09-19
1899 GATA1-defective immune-megakaryocytes as possible drivers of idiopathic pulmonary fibrosis
Gobbo, F.; Zingariello, M.; Verachi, P.; Falchi, M.; Arciprete, F.; Martelli, F.; Peli, A.; Mazzarini, M.; Vierstra, J.; Mead-Harvey, C.; Dueck, A. C.; Sarli, G.; Nava, S.; Sgalla, G.; Richeldi, L.; Migliaccio, A. R.
10.1101/2023.06.20.542249 — immunology — Posted on 2023-09-19
1900 State dependent constraints on claustrocortical communication and function
Marriott, B. A.; Do, A. D.; Portet, C.; Thellier, F.; Goutagny, R.; Jackson, J.
10.1101/2023.09.15.557951 — neuroscience — Posted on 2023-09-19
1901 Subchronic alteration of vestibular hair cells in mice: implications for multisensory gaze stabilization
Schenberg, L.; Palou, A.; Simon, F.; Bonnard, T.; Barton, C.-E.; Fricker, D.; Tagliabue, M.; Llorens, J.; Beraneck, M.
10.1101/2023.04.19.535725 — neuroscience — Posted on 2023-09-19
1904 Expanding the toolbox for phycobiliprotein assembly: phycoerythrobilin biosynthesis in Synechocystis
Heck, S.; Sommer, F. K.; Zehner, S.; Schroda, M.; Gehringer, M. M.; Frankenberg-Dinkel, N.
10.1101/2023.09.18.558311 — synthetic biology — Posted on 2023-09-19
1905 Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutation
Hovhannisyan, Y.; Li, Z.; Callon, D.; Suspene, R.; Batoumeni, V.; Canette, A.; Blanc, J.; Hocini, H.; Lefebvre, C.; El-Jahrani, N.; L'honore, A.; Kordeli, E.; Fornes, P.; Concordet, J.-P.; Tachdjian, G.; Rodriguez, A.-M.; Vartanian, J.-P.; Behin, A.; Wahbi, K.; Joanne, P.; Agbulut, O.
10.1101/2023.09.14.557734 — pathology — Posted on 2023-09-19
1909 Isofagomine inhibits multiple TcdB variants and protects mice from Clostridioides difficile induced mortality
Paparella, A. S.; Brew, I.; Hong, H. A.; Ferriera, W.; Cutting, S.; Lamiable-Oulaidi, F.; Popadynec, M.; Tyler, P. C.; Schramm, V. L.
10.1101/2023.09.19.558375 — biochemistry — Posted on 2023-09-19
1910 De novo designed Hsp70 activator dissolves intracellular condensates
Zhang, J. Z.; Greenwood, N.; Hernandez, J.; Cuperus, J. T.; Huang, B.; Ryder, B. D.; Queitsch, C.; Gestwicki, J. E.; Baker, D.
10.1101/2023.09.18.558356 — biochemistry — Posted on 2023-09-19
1911 Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies
Seebald, L. M.; Haratipour, P.; Jacobs, M. R.; Bernstein, H. M.; Kashemirov, B. A.; McKenna, C. M.; Imperiali, B.
10.1101/2023.09.19.558431 — biochemistry — Posted on 2023-09-19
1912 Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA charge mimicry to enhance chaperone efficiency
Lorton, B. M.; Warren, C.; Ilyas, H.; Nandigrami, P.; Hegde, S.; Cahill, S.; Lehman, S. M.; Shabanowitz, J.; Hunt, D.; Fiser, A.; Cowburn, D.; Shechter, D.
10.1101/2023.09.18.558337 — biochemistry — Posted on 2023-09-19
1913 Comparative genomics reveals the emergence of an outbreak-associated Cryptosporidium parvum population in Europe and its spread to the USA
Bellinzona, G.; Nardi, T.; Castelli, M.; Batisti Biffignandi, G.; Betson, M.; Blanchard, Y.; Bujila, I.; Chalmers, R.; Davidson, R.; D'Avino, N.; Enbom, T.; Gomes, J.; Karadjian, G.; Klotz, C.; Ostlund, E.; Plutzer, J.; Rimhanen-Finne, R.; Robinson, G.; Sannella, A. R.; Sroka, J.; Stensvold, C. R.; Troell, K.; Vatta, P.; Zalewska, B.; Bandi, C.; Sassera, D.; Caccio, S. M.
10.1101/2023.09.19.558430 — genomics — Posted on 2023-09-19
1914 Phylogenetics, Epidemiology and Temporal Patterns of Dengue Virus type 1 in Araraquara, Sao Paulo State
Souza, C.; Caleiro, G.; Claro, I.; de Jesus, J.; Coletti, T.; Maia, C.; Costa, A.; Inemami, M.; Ribeiro, A.; Felix, A.; de Paula, A.; Figueiredo, W.; Luna, E.; Sabino, E.; Romano, C. M.
10.1101/2023.09.18.558374 — genomics — Posted on 2023-09-19
1916 The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium
Charmant, O.; Gruchota, J.; Arnaiz, O.; Zangarelli, C.; Betermier, M.; Nowak, K.; Legros, V.; Chevreux, G.; Nowak, J.; Duharcourt, S.
10.1101/2023.09.19.558372 — genetics — Posted on 2023-09-19
1918 The paradox of plant preference: the malaria vectors Anopheles gambiae and Anopheles coluzzii select suboptimal food sources for their survival and reproduction
Pare, P. S. L.; Hien, D. F. D. S.; Youba, M.; Yerbanga, R. S.; Cohuet, A.; Gouagna, L.-C.; Diabate, A.; Ignell, R.; Dabire, R. K.; Gnankine, O.; Lefevre, T.
10.1101/2023.09.18.558223 — ecology — Posted on 2023-09-19
1919 Bone marrow-derived CCR5-expressing macrophages promote venous thrombus resolution by up-regulating plasminogen activators and VEGF
Nosaka, M.; Ishida, Y.; Kuninaka, Y.; Ishigami, A.; Kimura, A.; Taruya, A.; Tanaka, A.; Mukaida, N.; Kondo, T.
10.1101/2023.09.18.558360 — molecular biology — Posted on 2023-09-19
1920 Double-Strand Break Repair Pathways Differentially Affect Processing and Transduction by Dual AAV Vectors
Maurer, A. C.; Benyamini, B.; Fan, V. B.; Whitney, O. N.; Dailey, G. M.; Darzacq, X.; Weitzman, M. D.; Tjian, R.
10.1101/2023.09.19.558438 — molecular biology — Posted on 2023-09-19
1921 Collateral sensitivity increases the efficacy of a rationally designed bacteriophage combination to control Salmonella enterica
Acton, L.; Pye, H.; Thilliez, G.; Rafal, R.; Matthews, M.; Turner, K.; Yasir, M.; Holden, E.; Al-Khanaq, H.; Webber, M.; Adriaenssens, E. M.; Kingsley, R. A.
10.1101/2023.09.19.558423 — microbiology — Posted on 2023-09-19
1922 Isolation and characterization of persisters of the pathogenic microorganism Staphylococcus aureus
Liu, S.; Laman, P.; Jensen, S.; van der Wel, N.; Kramer, G.; Zaat, S. A. J.; Brul, S.
10.1101/2023.09.19.558453 — microbiology — Posted on 2023-09-19
1924 Commensal microbiome dysbiosis elicits IL-8 signaling to drive fibrotic skin disease
Zhang, W.; Peng, Q.; Huang, X.; Huang, Q.; Zhang, Z.; Li, F.; Zheng, N.; Shi, B.; Fan, Z.; Maj, T.; Chen, R.
10.1101/2023.09.19.558395 — microbiology — Posted on 2023-09-19
1925 Agtrevirus phage AV101 infect diverse extended spectrum β-lactamase E. coli by recognizing four different O-antigens
Sorensen, A. N.; Kalmar, D.; Lutz, V. T.; Klein-Sousa, V.; Taylor, N. M. I.; Sorensen, M. C. H.; Brondsted, L.
10.1101/2023.09.19.558411 — microbiology — Posted on 2023-09-19
1929 Determining the antiviral mechanism of MARCH2
Umthong, S.; Timilsina, U.; D'Angelo, M.; Stavrou, S.
10.1101/2023.09.18.558306 — microbiology — Posted on 2023-09-19
1930 Single-step genome engineering in the bee gut symbiont Snodgrassella alvi
Lariviere, P. J.; Ashraf, A. H. M. Z.; Leonard, S. P.; Miller, L. G.; Moran, N. A.; Barrick, J. E.
10.1101/2023.09.19.558440 — microbiology — Posted on 2023-09-19
1931 Endozoicomonas provides corals with steroid hormones during thermal stress
Ochsenkuhn, M.; Mohamed, A. R.; Haydon, T. D.; Coe, L. S.; Abrego, D.; Amin, S. A.
10.1101/2023.09.19.558257 — microbiology — Posted on 2023-09-19
1932 Evolutionary fingerprints of EMT in pancreatic cancers
Perelli, L.; Zhang, L.; Mangiameli, S.; Russell, A. J. C.; Giannese, F.; Peng, F.; Carbone, F.; Le, C.; Khan, H.; Citron, F.; Soeung, M.; Lam, T.; Lundgren, S.; Zhu, C.; Catania, D.; Feng, N.; Gurreri, E.; Sgambato, A.; Tortora, G.; Draetta, G.; Tonon, G.; Futreal, A.; Giuliani, V.; Carugo, A.; Viale, A.; Heffernan, T.; Wang, L.; Cittaro, D.; Chen, F.; Genovese, G.
10.1101/2023.09.18.558231 — cancer biology — Posted on 2023-09-19
1934 High-affinity binding to the SARS-CoV-2 spike trimer by a nanostructured, trivalent protein-DNA synthetic antibody
Xu, Y.; Zheng, R.; Prasad, A.; Liu, M.; Wan, Z.; Zhou, X.; Porter, R. M.; Sample, M.; Poppleton, E.; Procyk, J.; Liu, H.; Li, Y.; Wang, S.; Yan, H.; Sulc, P.; Stephanopoulos, N.
10.1101/2023.09.18.558353 — bioengineering — Posted on 2023-09-19
1935 RATTACA: Genetic predictions in Heterogeneous Stock rats offer a new tool for genetic correlation and experimental design
Johnson, B. B.; Sanches, T. M.; Okamoto, M. H.; Nguyen, K.-M.; Ortez, C. A.; Polesskaya, O.; Palmer, A. A.
10.1101/2023.09.18.558279 — genomics — Posted on 2023-09-19
1937 Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine
Browne, C. J.; Mews, P.; Zhou, X.; Holt, L. M.; Estill, M.; Futamura, R.; Schaefer, A.; Kenny, P. J.; Hurd, Y. L.; Shen, L.; Zhang, B.; Nestler, E. J.
10.1101/2023.09.19.558477 — neuroscience — Posted on 2023-09-19
1939 Estradiol propionate reduction of nuclear size in prostate cancer lines lacking DHRS7suggests DHRS7 absence as a biomarker for the effectiveness of estrogen therapy
Rizzotto, A.; Tollis, S.; Pham, N. T.; Zheng, Y.; Abad, M. A.; Wildenhain, J.; Jeyaprakash, A. A.; Auer, M.; Tyers, M. D.; Schirmer, E. C.
10.1101/2023.09.18.558190 — cancer biology — Posted on 2023-09-19
1941 The use of cultured human alveolar basal cells to mimic honeycomb formation in idiopathic pulmonary fibrosis
Blumer, S.; Khan, P.; Artysh, N.; Plappert, L.; Savic, S.; Knudsen, L.; Jonigk, D.; Kuehnel, M. P.; Prasse, A.; Hostettler, K. E.
10.1101/2023.09.19.557680 — cell biology — Posted on 2023-09-19
1943 Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
Krivec, N.; Couvreu de Deckersberg, E.; Lei, Y.; Al Delbany, D.; Regin, M.; Verhulst, S.; van Grunsven, L. A.; Sermon, K.; Spits, C.
10.1101/2023.09.19.558389 — cell biology — Posted on 2023-09-19
1944 Dynamics of diversified A-to-I editing in Streptococcus pyogenes is governed by changes in mRNA stability
Wulff, T. F.; Hahnke, K.; Lecrivain, A.-L.; Schmidt, K.; Ahmed-Begrich, R.; Finstermeier, K.; Charpentier, E.
10.1101/2023.09.19.555891 — molecular biology — Posted on 2023-09-19
1945 Gut microbiome remains stable following COVID-19 vaccination in healthy and immuno-compromised individuals
Boston, R. H.; Guan, R.; Beier, S.; Kalmar, L.; Horner, E. C.; Beristain-Covarrubias, N.; Yam-Puc, J. C.; Gerber, P. P.; Faria, L.; Kuroshchenkova, A.; Lindell, A. E.; Blasche, S.; Correa-Noguera, A.; Elmer, A.; Saunders, C.; Bermperi, A.; Jose, S.; Kingston, N.; COVID-19 BioResource Collaboration, ; Grigoriadou, S.; Staples, E.; Buckland, M.; Lear, S.; Matheson, N. J.; Benes, V.; Parkinson, C.; Thaventhiran, J. E.; Patil, K. R.
10.1101/2023.08.23.554506 — microbiology — Posted on 2023-09-19
1949 Schizosaccharomyces versatilis represents a distinct evolutionary lineage.
Etherington, G. J.; Gomez Gil, E.; Haerty, W.; Oliferenko, S.; Nieduszynski, C.
10.1101/2023.09.04.556188 — evolutionary biology — Posted on 2023-09-19
1950 Myomatrix arrays for high-definition muscle recording
Chung, B.; Zia, M.; Thomas, K. A.; Michaels, J. A.; Jacob, A.; Pack, A.; Williams, M. J.; Nagapudi, K.; Teng, L. H.; Arrambide, E.; Ouellette, L.; Oey, N.; Gibbs, R.; Anschutz, P.; Lu, J.; Wu, Y.; Kashefi, M.; Oya, T.; Kersten, R.; Mosberger, A. C.; O`Connell, S.; Wang, R.; Marques, H. G.; P. Mendes, A. R.; Lenschow, C.; Kondakath, G.; Kim, J. J.; Olson, W.; Quinn, K. N.; Perkins, P.; Gatto, G.; Thanawalla, A. R.; Coltman, S. K.; Kim, T.; Smith, T. S.; Binder-Markey, B.; Zaback, M.; Thompson, C. K.; Giszter, S.; Person, A.; Goulding, M.; Azim, E.; Thakor, N.; O`Connor, D.; Trimmer, B.; Q. Lima
10.1101/2023.02.21.529200 — neuroscience — Posted on 2023-09-19
1951 Ventromedial Frontoinsular Connectivity is Associated with Long-term Smoking Behavior Change in Aging
Thovinakere, N.; Ai, M.; Noriega de la Colina, A.; Walker, C.; Baracchini, G.; Tremblay-Mercier, J.; Villeneuve, S.; The PREVENT-AD Research Group, ; Spreng, N.; Geddes, M.
10.1101/2023.09.18.558264 — neuroscience — Posted on 2023-09-19
1952 Preclinical exploration of the DNA Damage Response pathway using the interactive neuroblastoma cell line explorer CLEAN.
Gabre, J.; Merseburger, P.; Claeys, A.; Siaw, J.; Bekaert, S.-L.; Speleman, F.; Hallberg, B.; Palmer, R.; Van den Eynden, J.
10.1101/2023.09.17.557904 — cancer biology — Posted on 2023-09-19
1954 ESR1 fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes
Yates, M. E.; Li, Z.; Li, Y.; Guzolik, H.; Wang, X.; Liu, T.; Hooda, J.; Atkinson, J. M.; Lee, A. V.; Oesterreich, S.
10.1101/2023.09.18.558175 — cancer biology — Posted on 2023-09-19
1958 A meta-analysis of bulk RNA-seq datasets identifies potential biomarkers and repurposable therapeutics against Alzheimers disease
Lamisa, A. B.; Ahammad, I.; Bhattacharjee, A.; Hossain, M. U.; Ishtiaque, A.; Chowdhury, Z. M.; Das, K. C.; Salimullah, M.; Keya, C. A.
10.1101/2023.09.17.558173 — bioinformatics — Posted on 2023-09-19
1961 The actin binding protein profilin 1 is critical for mitochondria function
Read, T.-A.; Cisterna, B. A.; Skruber, K.; Ahmadieh, S.; Lindamood, H. L.; Vitriol, J. A.; Shi, Y.; Lefebvre, A. E. Y. T.; Black, J. B.; Butler, M. T.; Bear, J. E.; Cherezova, A.; Ilatovskaya, D. V.; Weintraub, N. L.; Vitriol, E. A.
10.1101/2023.08.07.552354 — cell biology — Posted on 2023-09-19
1963 Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by memory B cells after mRNA but not adenovirus priming
Hartley, G. E.; Fryer, H. A.; Gill, P. A.; Boo, I.; Bornheimer, S. J.; Hogarth, P. M.; Drummer, H. E.; O'Hehir, R. E.; Edwards, E. S. J.; van Zelm, M. C.
10.1101/2023.09.15.557929 — immunology — Posted on 2023-09-19
1964 Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A
Lana-Elola, E.; Aoidi, R.; Llorian, M.; Gibbins, D.; Buechsenschuetz, C.; Bussi, C.; Flynn, H.; Gilmore, T.; Watson-Scales, S.; Haugsten Hansen, M.; Hayward, D.; Song, O.-R.; Brault, V.; Herault, Y.; Deau, E.; Meijer, L.; Snijders, A.; Gutierrez, M.; Fisher, E.; Tybulewicz, V.
10.1101/2023.09.18.558244 — developmental biology — Posted on 2023-09-19
1965 Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants
Reuschl, A.-K.; Thorne, L. G.; Whelan, M. X. V.; Ragazzini, R.; Furnon, W.; Cowton, V. M.; de Lorenzo, G.; Mesner, D.; Turner, J. E.; Dowgier, G.; Bogoda, N.; Bonfanti, P.; Palmarini, M.; Patel, A. H.; Jolly, C.; Towers, G. J.
10.1101/2022.07.12.499603 — microbiology — Posted on 2023-09-19
1967 WITHDRAWN: Neuron-dependent tuft cell expansion initiates sinonasal allergic Type 2 inflammation
Ortiz-Carpena, J. F.; Inclan-Rico, J. M.; Weiner, M. B.; Pastore, C. F.; Hung, L.-Y.; Wilkerson, W. B.; Lin, C.; Gentile, M. E.; Cohen, N. A.; Abdus-Saboor, I.; Vaughan, A. E.; Rossi, H. L.; Herbert, D. R.
10.1101/2023.07.04.547596 — immunology — Posted on 2023-09-19
1969 PMIpred: A physics-informed web server for quantitative Protein-Membrane Interaction prediction
van Hilten, N.; Verwei, N.; Methorst, J.; Nase, C.; Bernatavicius, A.; Risselada, H. J.
10.1101/2023.04.10.536211 — biophysics — Posted on 2023-09-19
1972 Frequent horizontal chromosome transfer between asexual fungal insect pathogens
Habig, M.; Grasse, A. V.; Mueller, J.; Stukenbrock, E. H.; Leitner, H.; Cremer, S.
10.1101/2023.09.18.558174 — genomics — Posted on 2023-09-19
1973 The discovery of an evolutionarily conserved enhancer within the MYEOV locus suggests an unexpected role for this non-coding region in cancer
Davidson, B. S.; Arcila-Galvis, J. E.; Trevisan-Herraz, M.; Mikulasova, A.; Brackley, C. A.; Russell, L. J.; Rico, D.
10.1101/2023.09.18.558245 — genomics — Posted on 2023-09-19
1976 Ancient and ongoing hybridization in the Oreochromis cichlid fishes
Ciezarek, A. G.; Mehta, T. K.; Man, A.; Ford, A.; Dorcas Kavembe, G.; Kasozi, N.; Ngatunga, B. P.; Shechonge, A. H.; Tamatamah, R.; Nyingi, D. W.; Cnaani, A.; Di Palma, F.; Turner, G. F.; Genner, M. J.; Haerty, W.
10.1101/2023.05.19.541459 — evolutionary biology — Posted on 2023-09-19
1977 A scenario for an evolutionary selection of ageing
Roget, T.; Macmurray, C.; Jolivet, P.; Meleard, S.; Rera, M.
10.1101/2022.03.11.483978 — evolutionary biology — Posted on 2023-09-19
1978 Engineering of human myotubes toward a mature metabolic and contractile phenotype
Dreher, S. I.; Grubba, P.; von Toerne, C.; Moruzzi, A.; Maurer, J.; Goj, T.; Birkenfeld, A. L.; Peter, A.; Loskill, P.; Hauck, S. M.; Weigert, C.
10.1101/2023.06.12.544344 — cell biology — Posted on 2023-09-19
1979 Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis
Wang, F.; Liu, X.; Huang, F.; Zhou, Y.; Wang, X.; Song, Z.; Wang, S.; Wang, X.; Shi, D.; Ruan, G.; Ji, X.; Zhang, E.; Tan, Z.; Ye, Y.; Wang, C.; Zhu, J.; Wang, W.
10.1101/2023.06.02.543432 — microbiology — Posted on 2023-09-19
1981 Human brain state dynamics reflect individual neuro-phenotypes
Lee, K.; Ji, J. L.; Fonteneau, C.; Berkovitch, L.; Rahmati, M.; Pan, L.; Repovs, G.; Krystal, J. H.; Murray, J. D.; Anticevic, A.
10.1101/2023.09.18.557763 — neuroscience — Posted on 2023-09-19
1982 Alleviating the barrier of adventitious roots formation in recalcitrant mature tissue by slow release of a synthetic auxin
Roth, O.; Yechezkel, S.; Serero, O.; Eliyahu, A.; Vints, I.; Tzeela, P.; Carignano, A.; Janacek, D. P.; Peters, V.; Kessel, A.; Dwivedi, V.; Carmeli-Weissberg, M.; Shaya, F.; Faigenboim-Doron, A.; Ung, K. L.; Pedersen, B. P.; Riov, J.; Klavins, E.; Dawid, C.; Hammes, U. Z.; Ben-Tal, N.; Napier, R.; Sadot, E.; Weinstain, R.
10.1101/2023.03.13.532257 — plant biology — Posted on 2023-09-19
1985 Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle
Vegas, A. D.; Madsen, S.; Cooke, K. C.; Carroll, L.; Khor, J. X. Y.; Turner, N.; Lim, X. Y.; Astore, M. A.; Morris, J.; Don, A. S.; Garfield, A.; Zarini, S.; Zemski Berry, K. A.; Ryan, A. P.; Bergman, B. C.; Brozinick, J. T.; James, D. E.; Burchfield, J. G.
10.1101/2023.03.10.532020 — cell biology — Posted on 2023-09-19
1989 Extensive long-range polycomb interactions and weak compartmentalization are hallmarks of human neuronal 3D genome
Pletenev, I. A.; Bazarevich, M.; Zagirova, D. R.; Kononkova, A. D.; Cherkasov, A. V.; Efimova, O. I.; Tiukacheva, E. A.; Morozov, K. V.; Ulianov, K. A.; Komkov, D.; Tvorogova, A. V.; Golimbet, V. E.; Kondratyev, N. V.; Razin, S. V.; Khaitovich, P.; Ulianov, S. V.; Khrameeva, E. A.
10.1101/2023.08.04.551939 — genomics — Posted on 2023-09-19
1990 Cross-feeding affects the target of resistance evolution to an antifungal drug
Durand, R.; Jalbert-Ross, J.; Fijarczyk, A.; Dube, A. K.; Landry, C. R.
10.1101/2023.05.03.539243 — genomics — Posted on 2023-09-19
1991 The Nucleotide Transformer: Building and Evaluating Robust Foundation Models for Human Genomics
Dalla-Torre, H.; Gonzalez, L.; Mendoza Revilla, J.; Lopez Carranza, N.; Henryk Grywaczewski, A.; Oteri, F.; Dallago, C.; Trop, E.; De Almeida, B. P.; Sirelkhatim, H.; Richard, G.; Skwark, M.; Beguir, K.; Lopez, M.; Pierrot, T.
10.1101/2023.01.11.523679 — genomics — Posted on 2023-09-19
1992 Analysis of regulatory network modules in hundreds of human stem cell lines reveals complex epigenetic and genetic factors contribute to pluripotency state differences between subpopulations
Arthur, T. D.; Nguyen, J. P.; D'Antonio-Chronowska, A.; Matsui, H.; Silva, N. S.; Joshua, I. N.; iPSCORE Consortium, ; Luchessi, A. D.; Young Greenwald, W. W.; D'Antonio, M.; Pera, M. F.; Frazer, K. A.
10.1101/2023.05.20.541447 — genomics — Posted on 2023-09-19
1994 A pangenomic atlas reveals that eco-evolutionary dynamics shape plant pathogen type VI secretion systems
Aoun, N.; Georgoulis, S. J.; Avalos, J. K.; Grulla, K. J.; Miqueo, K.; Tom, C.; Lowe-Power, T.
10.1101/2023.09.05.556054 — evolutionary biology — Posted on 2023-09-19
1995 Drivers of species knowledge across the Tree of Life
Mammola, S.; Adamo, M.; Antic, D.; Calevo, J.; Cancellario, T.; Cardoso, P.; Chamberlain, D.; Chialva, M.; Durucan, F.; Fontaneto, D.; Goncalves, D.; Martinez, A.; Santini, L.; Rubio-Lopez, I.; Sousa, R.; Villegas-Rios, D.; Verdes, A.; Correia, R. A.
10.1101/2023.03.27.534304 — ecology — Posted on 2023-09-19
2001 Thalamic spindles and upstates, but not ripples, coordinate cortico-cortical and hippocampo-cortical co-ripples in humans
Dickey, C. W.; Verzhbinsky, I. A.; Kajfez, S.; Rosen, B. Q.; Gonzalez, C. E.; Chauvel, P. Y.; Cash, S. S.; Pati, S.; Halgren, E.
10.1101/2022.09.15.507471 — neuroscience — Posted on 2023-09-19
2003 Induction of antiviral Interferon-Stimulated Genes (ISGs) by neuronal STING promotes the resolution of pain
Defaye, M.; Bradaia, A.; Abdullah, N.; Agosti, F.; Iftinca, M.; Soubeyre, V.; Svendsen, K.; Gill, G.; Cumenal, M.; Gheziel, N.; Martin, J.; Basso, L.; Bourinet, E.; Chiu, I.; Altier, C.
10.1101/2023.08.04.551993 — neuroscience — Posted on 2023-09-19
2004 Olfactory fear conditioning biases olfactory stem cell receptor fate
Liff, C. W.; Ayman, Y. R.; Jaeger, E. C. B.; Lee, H. S.; Kim, A.; Vina-Albarracin, A.; Marlin, B. J.
10.1101/2023.02.23.529692 — neuroscience — Posted on 2023-09-19
2006 Phosphorylation alters FMRP granules and determines their transport or protein synthesis abilities
Kharod, S. C.; Hwang, D.; Choi, H.; Yoon, K. J.; Castillo, P. E.; Singer, R. H.; Yoon, Y. J.
10.1101/2023.03.15.532613 — neuroscience — Posted on 2023-09-19
2007 Objective QC for diffusion MRI data: artefact detection using normative modelling
Cirstian, R.; Forde, N.; Sotiropoulos, S.; Andersson, J.; Beckmann, C.; Marquand, A.
10.1101/2023.06.30.546837 — neuroscience — Posted on 2023-09-19
2012 Exploring the Residue-Level Interactions between the R2ab Protein and Polystyrene Nanoparticles
Somarathne, R. P.; Misra, S. K.; Kariyawasam, C. S.; Kessl, J. J.; Sharp, J. S.; Fitzkee, N. C.
10.1101/2023.08.28.554951 — biophysics — Posted on 2023-09-19
2016 Structural basis of TRPV1 modulation by endogenous bioactive lipids
Arnold, W. R.; Mancino, A. S.; Moss, F. R.; Frost, A.; Julius, D.; Cheng, Y.
10.1101/2023.05.11.540281 — biochemistry — Posted on 2023-09-19
2018 Preimplantation Embryos Amplify Stress-Induced Changes in Sperm-Derived miRNA Content to Mediate Transgenerational Epigenetic Inheritance
Champroux, A.; Yang, T.; Dickson, D. A.; Meng, A.; Harrington, A.; Liaw, L.; Marzi, M.; Nicassio, F.; Schlaeger, T.; Feig, L.
10.1101/2023.04.21.537854 — genetics — Posted on 2023-09-19
2020 Convolutional networks can model the functional modulation of MEG responses during reading
van Vliet, M.; Rinkinen, O.; Shimizu, T.; Niskanen, A.-M.; Devereux, B.; Salmelin, R.
10.1101/2022.02.08.479654 — neuroscience — Posted on 2023-09-19
2021 Functional connectome through the human life span
Sun, L.; Zhao, T.; Liang, X.; Xia, M.; Li, Q.; Liao, X.; Gong, G.; Wang, Q.; Pang, C.; Yu, Q.; Bi, Y.; Chen, P.; Chen, R.; Chen, Y.; Chen, T.; Cheng, J.; Cheng, Y.; Cui, Z.; Dai, Z.; Deng, Y.; Ding, Y.; Dong, Q.; Duan, D.; Gao, J.-H.; Gong, Q.; Han, Y.; Han, Z.; Huang, C.-C.; Huang, R.; Zhong, S.; Li, L.; Lin, C.-P.; Lin, Q.; Liu, B.; Liu, C.; Liu, N.; Liu, Y.; Liu, Y.; Lu, J.; Ma, L.; Men, W.; Qin, S.; Qiu, J.; Qiu, S.; Si, T.; Tan, S.; Tang, Y.; Tao, S.; Wang, D.; Wang, F.; Wang, J.; Wang, P.; Wang, X.; Wang, Y.; Wei, D.; Wu, Y.; Xie, P.; Xu, X.; Xu, Y.; Xu, Z.; Yang, H.; Yang, L.; Zeng, Z.;
10.1101/2023.09.12.557193 — neuroscience — Posted on 2023-09-19
2022 Genetic Variants That Modify the Neuroendocrine Regulation of Foraging Behavior in C. elegans
Lee, H.; Boor, S. A.; Hilbert, Z. A.; Meisel, J. D.; Park, J.; Wang, Y.; McKeown, R. J.; Fischer, S.; Andersen, E. C.; Kim, D. H.
10.1101/2023.09.09.556976 — neuroscience — Posted on 2023-09-19
2023 Multimodal layer modelling reveals in-vivo pathology in ALS
Northall, A.; Doehler, J.; Weber, M.; Tellez, I.; Petri, S.; Prudlo, J.; Vielhaber, S.; Schreiber, S.; Kuehn, E.
10.1101/2023.06.28.546951 — neuroscience — Posted on 2023-09-19
2026 Physical mechanisms of red blood cell splenic filtration
Moreau, A.; Yaya, F.; Lu, H.; Surendranath, A.; Charrier, A.; Dehapiot, B.; Helfer, E.; Viallat, A.; Peng, Z.
10.1101/2023.01.10.523245 — biophysics — Posted on 2023-09-19
2029 Childhood-onset asthma is characterized by airway epithelial hillock-to-squamous differentiation in early life
Kersten, E. T. G.; Pett, J. P.; Malmstrom, K.; Chun, Y.; Jonker, M. R.; Wilbrey-Clark, A. L.; Worlock, K. B.; van den Berge, M.; Vermeulen, R. C. H.; Vonk, J. M.; Sebire, N.; Lohi, J.; Timens, W.; Teichmann, S.; Bunyavanich, S.; Nikolic, M. Z.; Nawijn, M. C.; Makela, M.; Meyer, K. B.; Koppelman, G. H.
10.1101/2023.07.31.549680 — genomics — Posted on 2023-09-19
2030 Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
Bilgic, M.; Wu, Q.; Suetsugu, T.; Tsunekawa, Y.; Shitamukai, A.; Kadota, M.; Nishimura, O.; Kuraku, S.; Shimogori, T.; Kiyonari, H.; Matsuzaki, F.
10.1101/2022.05.05.490846 — developmental biology — Posted on 2023-09-19
2031 Intra-ocular Predation of Fluoroquinolone-Resistant Pseudomonas aeruginosa and Serratia marcescens by Predatory Bacteria
Romanowski, E. G.; Brothers, K. M.; Calvario, R. C.; Stella, N. A.; Kim, T.; Elsayed, M.; Kadouri, D. E.; Shanks, R. M. Q.
10.1101/2023.09.17.558130 — microbiology — Posted on 2023-09-19
2033 Neural manifolds in V1 change with top-down signals from V4 targeting the foveal region
Morales-Gregorio, A.; Kurth, A. C.; Ito, J.; Kleinjohann, A.; Barthelemy, F. V.; Brochier, T.; Grün, S.; van Albada, S. J.
10.1101/2023.06.14.544966 — neuroscience — Posted on 2023-09-19
2036 Brain organoid-on-a-chip to create multiple domains in forebrain organoids
Tsai, Y.-C.; Ozaki, H.; Morikawa, A.; Shiraiwa, K.; Pin, A. P.; Salem, A. G.; Phommahasay, K. A.; Sugita, B. K.; Vu, C. H.; Mamoun Hammad, S.; Kamei, K.-i.; Watanabe, M.
10.1101/2023.09.18.558278 — bioengineering — Posted on 2023-09-18
2037 Higher-order combinatorial chromatin perturbations by engineered CRISPR-Cas12a for functional genomics
Hsiung, C. C.- S.; Wilson, C. M.; Sambold, N. A.; Dai, R.; Chen, Q.; Misiukiewicz, S.; Arab, A.; Teyssier, N.; O'Loughlin, T.; Cofsky, J.; Shi, J.; Gilbert, L. A.
10.1101/2023.09.18.558350 — genetics — Posted on 2023-09-18
2038 Functional networks of inhibitory neurons orchestrate synchrony in the hippocampus
Bocchio, M.; Vorobyev, A.; Sadeh, S.; Brustlein, S.; Dard, R.; Reichinnek, S.; EMILIANI, V.; Clopath, C.; Cossart, R.
10.1101/2023.09.18.558335 — neuroscience — Posted on 2023-09-18
2040 A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay
de Zoysa, T.; Hauke, A. C.; Iyer, N. R.; Marcus, E.; Ostrowski, S. M.; Fay, J. C.; Phizicky, E. M.
10.1101/2023.09.18.558340 — molecular biology — Posted on 2023-09-18
2042 Age-specific and compartment-dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons
Sleigh, J. N.; Mattedi, F.; Richter, S.; Ng, K.; Steinmark, I. E.; Ivanova, I.; Daraban, I. L.; Joshi, P. P.; Annuario, E.; Awale, S.; Yahioglu, G.; Mitchell, J. C.; Suhling, K.; Schiavo, G.; Vagnoni, A.
10.1101/2023.09.18.558344 — neuroscience — Posted on 2023-09-18
2045 Sweetwater: an underrated crude glycerol for sustainable lipid production in non-conventional yeasts
Malika Keita, V.; Lee, Y. Q.; Lakshmanan, M.; Ow, D. S.-W.; Staniland, P.; Staniland, J.; Savill, I.; Tee, K. L.; Wong, T. S.; Lee, D.-Y.
10.1101/2023.09.18.558176 — systems biology — Posted on 2023-09-18
2046 The circadian clock regulates PIF3 protein stability in parallel to red light
Liu, W.; Lowrey, H.; Leung, C. C.; Adamchek, C.; Du, J.; He, J.; Chen, M.; Gendron, J. M.
10.1101/2023.09.18.558326 — plant biology — Posted on 2023-09-18
2047 Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer
Chibaya, L.; Lusi, C. F.; DeMarco, K. D.; Kane, G. I.; Brassil, M. L.; Parikh, C. N.; Murphy, K. C.; Li, J.; Naylor, T. E.; Cerrutti, J.; Peura, J.; Pitarresi, J. R.; Zhu, L. J.; Fitzgerald, K. A.; Atukorale, P. U.; Ruscetti, M. A.
10.1101/2023.09.18.558307 — cancer biology — Posted on 2023-09-18
2048 Spatio-temporal Coordination of Active Deformation Forces and Wnt / Hippo-Yap Signaling in Hydra Regeneration
Suzuki, R.; Hiraiwa, T.; Tursch, A.; Hoger, S.; Hayashi, K.; Ozbek, S.; Holstein, T. W.; Tanaka, M.
10.1101/2023.09.18.558226 — biophysics — Posted on 2023-09-18
2049 casmini-tool: a comprehensive database for efficient and specific guide RNA design using dCasMINI
Lopp, S.; Yeo, R. W.; Jha, N.; Yang, X.; Alvarez, G.; Klappenbach, C.; Hart, D. O.; Qi, L. S.; Daley, T. P.
10.1101/2023.09.17.558168 — bioengineering — Posted on 2023-09-18
2054 Mimicking the regulatory state of a major facilitator superfamily sugar transporter
Hariharan, P.; Shi, Y.; Katsube, S.; Willibal, K.; Burrows, N. D.; Mitchell, P.; Bakhtiiari, A.; Stanfield, S.; Pardon, E.; Kaback, H. R.; Liang, R.; Steyaert, J.; Viner, R.; Guan, L.
10.1101/2023.09.18.558283 — molecular biology — Posted on 2023-09-18
2055 Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi
Adler, B. A.; Al-Shimary, M. J.; Patel, J. R.; Ambruster, E.; Colognori, D.; Charles, E. J.; Miller, K. V.; Lahiri, A.; Trinidad, M.; Boger, R.; Nomburg, J.; Beurnier, S.; Cui, M. L.; Barrangou, R.; Mutalik, V. K.; Schoeniger, J. S.; Pogliano, J. A.; Savage, D. F.; Doudna, J. A.; Cress, B. F.
10.1101/2023.09.18.558157 — microbiology — Posted on 2023-09-18
2056 Histone acetylation in an Alzheimer's disease cell model promotes homeostatic amyloid-reducing pathways
Xu, D. C.; Sas-Nowosielska, H.; Donahue, G.; Huang, H.; Pourshafie, N.; Good, C. R.; Berger, S. L.
10.1101/2023.09.18.558276 — neuroscience — Posted on 2023-09-18
2059 4D DYNAMIC SPATIAL BRAIN NETWORKS AT REST LINKED TO COGNITION SHOW ATYPICAL VARIABILITY AND COUPLING IN SCHIZOPHRENIA
Pusuluri, K.; Fu, Z.; Miller, R. L.; Pearlson, G. D.; Kochunov, P.; Van Erp, T. G. M.; Iraji, A.; Calhoun, V.
10.1101/2023.09.18.558295 — neuroscience — Posted on 2023-09-18
2064 Ventromedial Frontoinsular Connectivity is Associated with Long-term Smoking Behavior Change in Aging
Thovinakere, N.; Noriega de la Colina, A.; Ai, M.; Walker, C.; Baracchini, G.; Tremblay-Mercier, J.; Villeneuve, S.; Spreng, N.; Geddes, M.; The PREVENT-AD Research Group,
10.1101/2023.09.18.558264 — neuroscience — Posted on 2023-09-18
2065 Detection of idiosyncratic gaze fingerprint signatures in humans
Crockford, S. K.; Satta, E.; Severino, I.; Fiacchino, D.; Vitale, A.; Bertelsen, N.; Busuoli, E. M.; Mandelli, V.; Lombardo, M. V.
10.1101/2023.09.18.558217 — neuroscience — Posted on 2023-09-18
2069 Massively parallel in vivo Perturb-seq reveals cell type-specific transcriptional networks in cortical development
Zheng, X.; Wu, B.; Liu, Y.; Simmons, S. K.; Kim, K.; Clarke, G. S.; Ashiq, A.; Park, J.; Wang, Z.; Tong, L.; Wang, Q.; Xu, X.; Levin, J. Z.; Jin, X.
10.1101/2023.09.18.558077 — neuroscience — Posted on 2023-09-18
2070 Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast
Teyssonniere, E.; Trebulle, P.; Muenzner, J.; Loegler, V.; Ludwig, D.; Amari, F.; Mulleder, M.; Friedrich, A.; Hou, J.; Ralser, M.; Schacherer, J.
10.1101/2023.09.18.558197 — systems biology — Posted on 2023-09-18
2071 Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis
Casanova, A. G.; Roth, G. S.; Hausmann, S.; Lu, X.; Belmudes, L.; Bourova-Flin, E.; Flores, N. M.; Benitez, A. M.; Caporicci, M.; Vayr, J.; Blanchet, S.; Ielasi, F.; Rousseaux, S.; Hainaut, P.; Gozani, O.; Coute, Y.; Palencia, A.; Mazur, P. K.; Reynoird, N.
10.1101/2023.09.18.558201 — cancer biology — Posted on 2023-09-18
2077 Proteome-scale characterisation of protein motif interactome rewiring by disease mutations
Kliche, J.; Simonetti, L.; Krystkowiak, I.; Kuss, H.; Diallo, M.; Rask, E.; Nilsson, J.; Davey, N.; Ivarsson, Y.
10.1101/2023.09.18.558189 — biochemistry — Posted on 2023-09-18
2081 Decrypting the functional design of unmodified translation elongation factor P
Tomasiunaite, U.; Kielkowski, P.; Krafczyk, R.; Forne, I.; Imhof, A.; Jung, K.
10.1101/2023.09.18.558224 — microbiology — Posted on 2023-09-18
2084 A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution
Nardone, S.; De Luca, R.; Zito, A.; Klymko, N.; Nicoloutsopoulos, D.; Amsalem, O.; Brannigan, C.; Resch, J. M.; Jacobs, C. L.; Pant, D.; Veregge, M.; Srinivasan, H.; Grippo, R. M.; Yang, Z.; Zeidel, M. L.; Andermann, M. L.; Harris, K. D.; Tsai, L. T.; Arrigoni, E.; Verstegen, A. M. J.; Saper, C. B.; Lowell, B. B.
10.1101/2023.09.18.558047 — neuroscience — Posted on 2023-09-18
2085 High-resolution 7T fMRI reveals the visual sensory zone of the human claustrum
Coates, A.; Linhardt, D.; Windischberger, C.; Ischebeck, A.; Zaretskaya, N.
10.1101/2023.09.18.558213 — neuroscience — Posted on 2023-09-18
2086 Attenuating midline thalamus bursting to mitigate absence epilepsy
Dong, P.; Bakhurin, K.; Li, Y.; Mikati, M. A.; Cui, J.; Grill, W. M.; Yin, H.; Yang, H.
10.1101/2023.09.18.558258 — neuroscience — Posted on 2023-09-18
2088 Enhancement of neurophysiological signatures of working memory by combined yoga and tDCS
Sefat, O.; Salehinejad, M. A.; Danilewitz, M.; Shalbaf, R.; Vila-Rodriguez, F.
10.1101/2023.09.18.558292 — neuroscience — Posted on 2023-09-18
2091 The clinical, genomic, and transcriptomic landscape of BRAF mutant cancers
Kazandjian, S.; Rousselle, E.; Dankner, M.; Cescon, D. W.; Spreafico, A.; Ma, K.; Kavan, P.; Batist, G.; Rose, A. A. N.
10.1101/2023.09.15.557847 — cancer biology — Posted on 2023-09-18
2093 AITeQ: A machine learning framework for Alzheimer's prediction using a distinctive 5-gene signature
Ahammad, I.; Lamisa, A. B.; Bhattacharjee, A.; Jamal, T. B.; Arefin, M. S.; Chowdhury, Z. M.; Hossain, M. U.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.09.16.558056 — bioinformatics — Posted on 2023-09-18
2094 Engineered transcription-associated Cas9 targeting in eukaryotic cells
Goldberg, G. W.; Kogenaru, M.; Keegan, S.; Haase, M. A. B.; Kagermazova, L.; Arias, M. A.; Onyebeke, K.; Adams, S.; Fenyo, D.; Noyes, M. B.; Boeke, J. D.
10.1101/2023.09.18.558319 — bioengineering — Posted on 2023-09-18
2095 Eukaryotic-driven directed evolution of Cas9 nucleases
Ruta, G. V.; Ciciani, M.; Kheir, E.; Gentile, M. D.; Amistadi, S.; Casini, A.; Cereseto, A.
10.1101/2023.09.18.558227 — bioengineering — Posted on 2023-09-18
2100 CCAR1 promotes DNA repair via an unanticipated role in alternative splicing
Karasu, M. E.; Joseph, B.; Mironov, A.; Schroeder, M. S.; Gvozdenovic, A.; Zavolan, M.; Corn, J. E.
10.1101/2023.09.18.557780 — molecular biology — Posted on 2023-09-18
2103 Local adaptation of Arabidopsis thaliana in a small geographic region with mild environmental clines
Wijfjes, R. Y.; Boesten, R.; Becker, F. F. M.; Theeuwen, T. P. J. M.; Snoek, B. L.; Mastoraki, M.; Verheijen, J. J.; Guvencli, N.; Denkers, L.-A. M.; Koornneef, M.; van Eeuwijk, F. A.; Smit, S.; de Ridder, D.; Aarts, M. G. M.
10.1101/2023.09.18.558200 — plant biology — Posted on 2023-09-18
2104 Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets
Stylianou, M.; Kisby, T.; Despotopoulou, D.; Parker, H.; Thawley, A.; Arashvand, K.; Lozano, N.; MacDonald, A. S.; Kostarelos, K.
10.1101/2023.09.18.558196 — bioengineering — Posted on 2023-09-18
2105 The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sites
Hempelmann, P.; Lolicato, F.; Graziadei, A.; Brown, R. D. R.; Spiegel, S.; Rappsilber, J.; Nickel, W.; Höglinger, D.; Jamecna, D.
10.1101/2023.09.18.557036 — cell biology — Posted on 2023-09-18
2106 Circular RNA profiling identifies circ5078 as a BMPR2-derived regulator of endothelial translation
VandenBroek, M. M.; Sharp, M. C.; Thompson, P.; Fagbola, E.; Quilty, D.; Mewburn, J. D.; Theilmann, A. L.; Archer, S. L.; Renwick, N.; Ormiston, M. L.
10.1101/2023.09.18.556866 — molecular biology — Posted on 2023-09-18
2107 A Parasite Odyssey: An RNA virus concealed in Toxoplasma gondii
Gupta, P.; Hiller, A.; Chowdhury, J.; Lim, D.; Lim, D.; Babaian, A.; Pereira, L.; Morales, A.
10.1101/2023.09.17.558162 — microbiology — Posted on 2023-09-18
2108 Alpha-toxin elicited CX3CL1-release via ADAM10 in Staphylococcus aureus pneumoniaimpairs bactericidal function of human monocytes
Mairpady Shambat, S.; Chen, P.; Barilla, R. M.; Huemer, M.; Snaell, J.; Welin, A.; Cohen, T. S.; Takahashi, V.; Berry, S. B.; Gomez-Mejia, A.; Schweizer, T. A.; Cunoosamy, D. M.; Cajander, S.; Lourdaa, M.; Ozenci, V.; Marques Maggio, E.; Schuepbach, R. A.; Stralin, K.; Zinkernagel, A. S.; Norrby-Teglund, A.; Svensson, M.
10.1101/2023.09.17.554633 — microbiology — Posted on 2023-09-18
2110 Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by memory B cells after with mRNA but not adenovirus priming
Hartley, G. E.; Fryer, H. A.; Gill, P. A.; Boo, I.; Bornheimer, S. J.; Hogarth, P. M.; Drummer, H. E.; O'Hehir, R. E.; Edwards, E. S. J.; van Zelm, M. C.
10.1101/2023.09.15.557929 — immunology — Posted on 2023-09-18
2111 Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor
Blum, S. M.; Zlotoff, D. A.; Smith, N. P.; Kernin, I. J.; Ramesh, S.; Zubiri, L.; Caplin, J.; Tirard, A.; Sen, P.; Song, Y.; Barth, J. L.; Slowikowski, K.; Nasrallah, M.; Tantivit, J.; Manakongtreecheep, K.; Arnold, B. Y.; McGuire, J.; Pinto, C. J.; McLoughlin, D.; Jackson, M.; Chan, P.; Lawless, A.; Sharova, T.; Nieman, L. T.; Gainor, J. F.; Juric, D.; Mino-Kenudsen, M.; Sullivan, R. J.; Boland, G. M.; Stone, J. R.; Thomas, M. F.; Neilan, T. G.; Reynolds, K. L.; Villani, A.-C.
10.1101/2023.09.15.557794 — immunology — Posted on 2023-09-18
2112 NeuroMechFly 2.0, a framework for simulating embodied sensorimotor control in adult Drosophila
Wang-Chen, S.; Stimpfling, V. A.; Ozdil, P. G.; Genoud, L.; Hurtak, F.; Ramdya, P.
10.1101/2023.09.18.556649 — neuroscience — Posted on 2023-09-18
2113 Direct and indirect responses of the Arabidopsis transcriptome to an induced increase in trehalose 6-phosphate
Avidan, O.; Martins, M. C. M.; Feil, R.; Lohse, M.; Giorgi, F. M.; Schlereth, A.; Lunn, J. E.; Stitt, M.
10.1101/2023.09.18.555309 — plant biology — Posted on 2023-09-18
2114 Impact of water deficit on single grapevine berry ripening
Shi, M.; Savoi, S.; Simonneau, T.; Doligez, A.; Pantin, F.; Torregrosa, L. J.-M.; Romieu, C.
10.1101/2023.09.18.557818 — physiology — Posted on 2023-09-18
2115 Klebsiella Pneumoniae turns more virulent under flow stresses in capillary like microchannels
Jain, S.; Singh, A.; Tiwari, N.; Naik, A.; Chatterjee, R.; Chakravortty, D.; Basu, S.
10.1101/2023.09.18.558194 — biophysics — Posted on 2023-09-18
2116 Transposable element abundance subtly contributes to lower fitness in maize
Stitzer, M. C.; Khaipho-Burch, M. B.; Hudson, A. I.; Song, B.; Valdes-Franco, J. A.; Ramstein, G. P.; Feschotte, C.; Buckler, E. S.
10.1101/2023.09.18.557618 — evolutionary biology — Posted on 2023-09-18
2117 Controlled experiment finds no detectable citation bump from Twitter promotion
Branch, T.; C?te, I. M.; David, S. R.; Drew, J. A.; LaRue, M.; Marquez, M. C.; Parsons, E. C. M.; Rabaiotti, D.; Shiffman, D.; Steen, D. A.; Wild, A. L.
10.1101/2023.09.17.558161 — scientific communication and education — Posted on 2023-09-18
2118 Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutation
Hovhannisyan, Y.; Li, Z.; Callon, D.; Suspene, R.; Batoumeni, V.; Canette, A.; Blanc, J.; Hocini, H.; Lefebvre, C.; El-Jahrani, N.; L'honore, A.; Kordeli, E.; Fornes, P.; Concordet, J.-P.; Tachdjian, G.; Rodriguez, A.-M.; Vartanian, J.-P.; Behin, A.; Wahbi, K.; Joanne, P.; Agbulut, O.
10.1101/2023.09.14.557734 — pathology — Posted on 2023-09-18
2119 Data-Driven Strain Design Towards Mitigating Biomanufacturing Stresses
Phaneuf, P. V.; Kim, S. H.; Rychel, K.; Rode, C.; Beulig, F.; Palsson, B. O.; Yang, L.
10.1101/2023.09.17.558093 — bioengineering — Posted on 2023-09-18
2120 In vivo Imaging using Surface Enhanced Spatially Offset Raman Spectroscopy (SESORS): Balancing Sampling Frequency to Improve Overall Image Acquisition
Nicolson, F.; Andreiuk, B.; Lee, E.; O'Donnell, B.; Whitley, A.; Riepl, N.; Burkhart, D.; Cameron, A.; Protti, A.; Rudder, S.; Yang, J.; Mabbott, S.; Haigis, K. M.
10.1101/2023.09.17.558110 — bioengineering — Posted on 2023-09-18
2121 Using recurrent neural networks to detect supernumerary chromosomes in fungal strains causing blast diseases
Gyawali, N.; Hao, Y.; Lin, G.; Huang, J.; Bika, R.; Daza, L. C.; Zheng, H.; Cruppe, G.; Caragea, D.; Cook, D.; Valent, B.; Liu, S.
10.1101/2023.09.17.558148 — genomics — Posted on 2023-09-18
2122 Probing Molecular Diversity and Ultrastructure of Brain Cells with Fluorescent Aptamers
Lu, X.; Wu, Y.; Li, P.; Fang, T.; Schalek, R. L.; Su, Y.; Carter, J. D.; Gupta, S.; Jain, V.; Janjic, N.; Lichtman, J. W.
10.1101/2023.09.18.558240 — neuroscience — Posted on 2023-09-18
2123 GABA, glucose and insulin orchestrate CD4+ T cells effector functions
Jin, Z.; Hammoud, H.; Bhandage, A. K.; Korol, S. V.; Trujeque-Ramos, O.; Koreli, S.; Chowdhury, A. I.; Sandbaumhuter, F. A.; Jansson, E.; Bergstein, P.; Andren, P.; Kamali-Moghaddam, M.; Birnir, B.
10.1101/2023.04.18.537327 — physiology — Posted on 2023-09-18
2126 Homo- and heterodimerization of bHLH transcription factors balance stemness and bipotential differentiation in the Drosophila gut
Puig-Barbe, A.; Dettmann, S.; Nirello, V. D.; Azami, S.; Edgar, B. A.; Varga-Weisz, P.; Korzelius, J.; de Navascues, J.
10.1101/685347 — developmental biology — Posted on 2023-09-18
2129 Immunometabolic reprogramming by LRH-1/NR5A2 pharmacological activation resolves inflammation in immune cells of type 1 diabetes mellitus individuals and improves human islet engraftment and function
Cobo-vuilleumier, N.; Rodriguez-Fernandez, S.; Lopez-Noriega, L.; Lorenzo, P. I.; Franco, J. M.; Lachaud, c. C.; Martin-Vazquez, E.; Araujo Legido, R.; Dorronsoro, A.; Lopez-Fernandez-Sobrino, R.; Salas-Lloret, D.; van Overbeek, N.; Ramos-Rodriguez, M.; Mateo-Rodriguez, C.; Hidalgo, L.; Nano, R.; Arroba, A. I.; Campos Caro, A.; Vertegaal, A. C.; Martin Montalvo, A.; Martin, F.; Aguilar-Diosdado, M.; Piemonti, L.; Pasquali, L.; Gonzalez Prieto, R.; Garcia Sanchez, M. I.; Martinez-Brocca, M.; Vives-Pi, M.; Gauthier, B. R.
10.1101/2023.09.18.558230 — cell biology — Posted on 2023-09-18
2130 Nanopore sequencing for accurate bacterial outbreak tracing
Lohde, M.; Wagner, G. E.; Dabernig-Heinz, J.; Viehweger, A.; Stein, C.; Braun, S. D.; Monecke, S.; Marquet, M.; Ehricht, R.; Pletz, M. W.; Brandt, C.
10.1101/2023.09.15.556300 — molecular biology — Posted on 2023-09-18
2132 Molecular pathways and cellular subsets associated with adverse clinical outcomes in overlapping immune-related myocarditis and myositis
Siddiqui, B. A.; Palaskas, N. L.; Basu, S.; Dai, Y.; He, Z.; Yadav, S. S.; Allison, J.; Sheth, R.; Tummala, S.; Buja, L. M.; Bhattacharjee, M.; Iliescu, C. A.; Rawther-Karedath, A.; Deswal, A.; Wang, L.; Sharma, P.; Subudhi, S. K.
10.1101/2023.09.15.556590 — immunology — Posted on 2023-09-18
2134 Increased neurovirulence of omicron BA.5 and XBB variants over BA.1 in K18-hACE2 mice and human brain organoids
Stewart, R.; Yan, K.; Ellis, S. A.; Bishop, C. R.; Dumenil, T.; Tang, B.; Nguyen, W.; Larcher, T.; Parry, R.; Sng, J. D. J.; Khromykh, A. A.; Sullivan, R. K. P.; Lor, M.; Meunier, F. A.; Rawle, D. J.; Suhrbier, A.
10.1101/2022.12.22.521696 — microbiology — Posted on 2023-09-18
2135 Conserved cell-type specific signature of resilience to Alzheimer's disease nominates role for excitatory intratelencephalic cortical neurons
Telpoukhovskaia, M. A.; Hadad, N.; Gurdon, B.; Dai, Y.; Ouellette, A. R.; Neuner, S. M.; Dunn, A. R.; Willcox, J. A. L.; Wu, Y.; Dumitrescu, L.; Bellur, O.; Zhang, J.-G.; O'Connell, K. M. S.; Dammer, E. B.; Seyfried, N. T.; Muzumdar, S.; Gillis, J.; Robson, P.; Arnold, M.; Hohman, T. J.; Philip, V.; Menon, V.; Kaczorowski, C. C.
10.1101/2022.04.12.487877 — neuroscience — Posted on 2023-09-18
2136 Genome engineering by RNA-guided transposition for Anabaena PCC 7120
Arevalo, S.; Rico, D. P.; Abarca, D.; Dijkhuizen, L. W.; Sarasa-Buisan, C.; Lindblad, P.; Flores, E.; Nierzwicki-Bauer, S.; Schluepmann, H.
10.1101/2022.09.18.508393 — synthetic biology — Posted on 2023-09-18
2138 Default mode network spatio-temporal electrophysiological signature and causal role in creativity
Bartoli, E.; Devara, E.; Dang, H. Q.; Rabinovich, R.; Mathura, R. K.; Anand, A.; Pascuzzi, B. R.; Adkinson, J.; Bijanki, K. R.; Sheth, S. A.; Shofty, B.
10.1101/2023.09.13.557639 — neuroscience — Posted on 2023-09-18
2140 Unsaturated intercellular vapor pressure is relevant for leaf water heavy isotope enrichment
Angove, C.; Lehman, M.; Saurer, M.; Tang, Y.; Kilpeläinen, P.; Kahmen, A.; Schiestl-Aalto, P. P.; Tikkasalo, O.-P.; Bäck, J. K.; Rinne-Garmston, K. T.
10.1101/2023.09.12.557463 — plant biology — Posted on 2023-09-18
2141 A first comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas.
Gibert, M. K.; Zhang, Y.; Saha, S.; Marcinkiewicz, P.; Dube, C.; Hudson, K.; Sun, Y.; Bednarek, S.; Chagari, B.; Sarkar, A.; Roig-Laboy, C.; Neace, N.; Saoud, K.; Setiady, I.; Hanif, F.; Kumar, P.; Kefas, B.; Abounader, R.
10.1101/2023.09.12.557444 — cancer biology — Posted on 2023-09-18
2142 Exploring associations between the teat apex metagenome and Staphylococcus aureus intramammary infection risk in primiparous cows under organic directives
Dean, C. J.; Pena-Mosca, F.; Ray, T.; Wehri, T. J.; Sharpe, K.; Antunes, A.; Doster, E.; Fernandes, L.; Calles, V. F.; Bauman, C.; Godden, S. M.; Heins, B.; Pinedo, P.; Machado, V. S.; Caixeta, L. S.; Noyes, N.
10.1101/2023.09.12.557435 — ecology — Posted on 2023-09-18
2145 Leishmania infantum-exploited Nrf2 transcription factor as a virulence process to escape macrophage-driven ferroptosis-like leishmanicidal process
Coste, A.; Blot, C.; Coulson, K.; Salon, M.; Tertrais, M.; Planes, R.; Santoni, K.; Authier, H.; Jacquemin, G.; Rahabi, M.; Parny, M.; Raymond-Letron, I.; Meunier, E.; Lefevre, L.
10.1101/2023.09.15.557964 — microbiology — Posted on 2023-09-18
2147 Assessment of behavioral flexibility in mice with conditional deletion of metabotropic glutamate receptor 2 from Emx1-lineage neurons
Chang, D. S.; Littlepage-Saunders, M.; Hochstein, M. J.; Matteo, C. J.; Amelga, K.; Homanics, G. E.; Johnson, K. A.
10.1101/2023.09.15.558004 — neuroscience — Posted on 2023-09-18
2148 A Functional Exodermal Suberin is Key for Plant Nutrition and Growth in Potato
Company-Arumi, D.; Montells, C.; Iglesias, M.; Margui, E.; Verdaguer, D.; Vogel-Miku, K.; Kelemen, M.; Figueras, M.; Antico, E.; Serra, O.
10.1101/2023.09.14.557788 — plant biology — Posted on 2023-09-18
2153 Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water
Zizelski Valenci, G.; Ohad, S.; Robinstein, M.; Assaly, S.; Kutikov, I.; Groisman, L.; Murik, O.; Zeevi, D. A.; Ben David, R.; Farber, A.; Dveyrin, Z.; Rorman, E.; Nissan, I.
10.1101/2023.09.14.557692 — microbiology — Posted on 2023-09-18
2155 Bayesian modeling disentangles language versus executive control disruption in stroke
Hartwigsen, G.; Lim, J.-S.; Bae, H.-J.; Yu, K.-H.; Kuijf, H. J.; Weaver, N. A.; Biesbroek, J. M.; Kopal, J.; Bzdok, D.
10.1101/2023.08.06.552147 — neuroscience — Posted on 2023-09-18
2156 NDH complex-mediated cyclic electron flow in bundle sheath cells enables C4 photosynthesis
Ermakova, M.; Woodford, R.; Fitzpatrick, D.; Zwahlen, S.; Farquhar, G.; von Caemmerer, S.; Furbank, R. T.
10.1101/2023.09.17.558135 — plant biology — Posted on 2023-09-18
2158 Improved Protein Model in SPICA Force Field
Yamada, T.; Miyazaki, Y.; Harada, S.; Kumar, A.; Vanni, S.; Shinoda, W.
10.1101/2023.09.15.557852 — biophysics — Posted on 2023-09-18
2162 A proposed function for the red body of Nannochloropsis in the formation of the recalcitrant cell wall polymer, algaenan
Gee, C. W.; Andersen-Ranberg, J.; Rosen, R. Z.; Jorgens, D.; Grob, P.; Holman, H.-Y.; Niyogi, K. K.
10.1101/2023.09.17.558137 — cell biology — Posted on 2023-09-17
2165 Basal spot junctions of epithelial tissues respond to morphogenetic forces and regulate Hippo signalling
Kroeger, B.; Manning, S. A.; Fonseka, Y.; Oorschot, V.; Crawford, S. A.; Ramm, G.; Harvey, K. F.
10.1101/2023.09.17.558144 — cell biology — Posted on 2023-09-17
2169 Differential effects of IL4I1 protein on lymphocytes from healthy and multiple sclerosis patients
Davis, S. E.; Hu, J.; Nanescu, S. E.; Kumar, M. N.; Baydyuk, M.; Oft, H.; Amjad, F. S.; Wellstein, A.; Huang, J.
10.1101/2023.09.17.558132 — neuroscience — Posted on 2023-09-17
2170 PERK modulation, with GSK2606414, Sephin1 or salubrinal, failed to produce therapeutic benefits in the SOD1G93A mouse model of ALS
Vieira, F. G.; Tassinari, V. R.; Kidd, J. D.; Moreno, A.; Thompson, K.; Perrin, S.; Gill, A.; Hatzipetros, T.
10.1101/2023.09.17.558143 — neuroscience — Posted on 2023-09-17
2172 Neural correlates of visual object recognition in rats
Rhee, J. Y.; Echavarria, C.; Soucy, E.; Greenwood, J.; Masis, J. A.; Cox, D. D.
10.1101/2023.09.17.555183 — neuroscience — Posted on 2023-09-17
2174 NDH complex-mediated cyclic electron flow in bundle sheath cells enables C4 photosynthesis
Ermakova, M.; Woodford, R.; Fitzpatrick, D.; Zwahlen, S.; Farquhar, G.; von Caemmerer, S.; Furbank, R. T.
10.1101/2023.09.17.558135 — plant biology — Posted on 2023-09-17
2177 Mechanical regulation of cell fate transitions underlying colorectal cancer metastasis formation
van der Net, M. C.; Vliem, M. J.; Kemp, L. J. S.; Perez-Gonzalez, C.; Strating, E. A.; Krotenberg-Garcia, A.; Houtekamer, R. M.; van den Anker, K. B.; Monster, J. L.; Snippert, H. J. G.; Khalil, A. A.; van Rheenen, J.; Suijkerbuijk, S. J.; Kranenburg, O.; Matic Vignjevic, D.; Gloerich, M.
10.1101/2023.09.17.557771 — cancer biology — Posted on 2023-09-17
2180 Hypoxia-inducible factor-2 (HIF2) regulates alveolar regeneration after repetitive injury
McCall, A. S.; Tanjore, H.; Burman, A.; Sherrill, T.; Chapman, M.; Calvi, C. L.; Camarata, J.; Hunt, R. P.; Nichols, D.; Banovich, N.; Lawson, W. E.; Gokey, J. J.; Kropski, J. A.; Blackwell, T. S.
10.1101/2023.09.17.557477 — cell biology — Posted on 2023-09-17
2182 Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody
Phan, T.; Zitzmann, C.; Chew, K. W.; Smith, D. M.; Daar, E. S.; Wohl, D. A.; Eron, J. J.; Currier, J. S.; Hughes, M. D.; Choudhary, M. C.; Deo, R.; Li, J. Z.; Ribeiro, R. M.; Ke, R.; Perelson, A. S.
10.1101/2023.09.14.557679 — immunology — Posted on 2023-09-17
2183 Temporal profiling of human lymphoid tissues reveals coordinated defence to viral challenge
Coates, M. L.; Richoz, N.; Tuong, Z. K.; Bowyer, G.; Lee, C. Y. C.; Ferdinand, J. R.; Gillman, E.; McClure, M.; Di Marco Barros, R.; Stewart, B. J.; Clatworthy, M. R.
10.1101/2023.09.15.558006 — immunology — Posted on 2023-09-17
2184 Reinstatement of CDX2 as a differentiation therapy for colorectal cancers
Sinha, S.; Alcantara, J.; Perry, K.; Castillo, V.; Espinoza, C. R.; Taheri, S.; Vidales, E.; Tindle, C.; Adel, A.; Amirfakhri, S.; Sawires, J. R.; Yang, J.; Bouvet, M.; Sahoo, D.; Ghosh, P.
10.1101/2023.09.13.557628 — cancer biology — Posted on 2023-09-17
2186 The diverse evolutionary histories of domesticated metaviral capsid genes in mammals
Henriques, W. S.; Young, J. M.; Nemudryi, A.; Nemudraia, A.; Wiedenheft, B.; Malik, H. S.
10.1101/2023.09.17.558119 — bioinformatics — Posted on 2023-09-17
2189 Intra-ocular Predation of Fluoroquinolone-Resistant Pseudomonas aeruginosa and Serratia marcescens by the Predatory Bacteria
Romanowski, E. G.; Brothers, K. M.; Calvario, R. C.; Stella, N. A.; Kim, T.; Elsayed, M.; Kadouri, D. E.; Shanks, R. M. Q.
10.1101/2023.09.17.558130 — microbiology — Posted on 2023-09-17
2190 Human adolescent brain network development is different for paralimbic versus neocortical systems
Dorfschmidt, L.; Vasa, F.; White, S. R.; Garcia, R. R.; Kitzbichler, M. G.; Bethlehem, R. A. I.; Seidlitz, J.; Vertes, P.; Bullmore, E. T.
10.1101/2023.09.17.558126 — neuroscience — Posted on 2023-09-17
2196 A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus
Zhang, Y.; Zhang, M.; Wu, H.; Wang, X.; Zheng, H.; Feng, J.; Wang, J.; Luo, L.; Xiao, H.; Qiao, C.; Li, X.; Zheng, Y.; Huang, W. J.; Wang, Y.; Wang, Y.; Shi, Y.; Feng, J.; Chen, G.
10.1101/2023.09.17.558100 — immunology — Posted on 2023-09-17
2198 Spinal inhibitory neurons degenerate before motor neurons and excitatory neurons in a mouse model of ALS
Montanana-Rosell, R.; Selvan, R.; Hernandez-Varas, P.; Kaminski, J. M.; Ahlmark, D. B.; Kiehn, O.; Allodi, I.
10.1101/2023.09.17.558103 — neuroscience — Posted on 2023-09-17
2199 Auranofin induces lethality driven by reactive oxygen species in high-grade serous ovarian cancer cells
Abdalbari, F. H.; Jaramillo, E. M.; Forgie, B. N.; Tran, E.; Zorytcha, E.; Goyeneche, A. A.; Telleria, C. M.
10.1101/2023.09.13.557629 — cancer biology — Posted on 2023-09-17
2201 Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists
Sheng, D.; Yue, C.; Jin, F.; Wang, Y.; Ichikawa, M.; Yu, Y.; Guo, C.-R.; Hattori, M.
10.1101/2023.09.15.558037 — biophysics — Posted on 2023-09-17
2206 Archaic Introgression Shaped Human Circadian Traits
Velazquez-Arcelay, K.; Colbran, L. L.; McArthur, E.; Brand, C. M.; Rinker, D. C.; Siemann, J. K.; McMahon, D. G.; Capra, J. A.
10.1101/2023.02.03.527061 — evolutionary biology — Posted on 2023-09-17
2207 Sperm Cell Painting: A Mechanism Driven Approach for Drug Discovery in Human Spermatozoa
Johnston, Z. C.; Gruber, F. S.; Myles, R.; Kane, S. V.; Richardson, A.; Day, D. P.; Wilson, C.; Read, K. D.; Gilbert, I. H.; Martins da Silva, S.; Barratt, C. L. R.; Swedlow, J. R.
10.1101/2023.09.15.557919 — cell biology — Posted on 2023-09-17
2208 Metabolic adaptation pilots the differentiation of human hematopoietic cells
Racine, L.; Parmentier, R.; Niphadkar, S.; Laxman, S.; Martignoles, J.-A.; Delhommeau, F.; Paldi, A.
10.1101/2023.09.17.558120 — cell biology — Posted on 2023-09-17
2216 Early Deficits in Dentate Circuit and Behavioral Pattern Separation after Concussive Brain Injury
Corrubia, L.; Huang, A.; Nguyen, S.; Shiflett, M. W.; Jones, M.; Ewell, L.; Santhakumar, V.
10.1101/2023.06.22.546120 — neuroscience — Posted on 2023-09-17
2219 Digitize your Biology! Modeling multicellular systems through interpretable cell behavior
Johnson, J. A. I.; Stein-O'Brien, G. L.; Booth, M.; Heiland, R.; Kurtoglu, F.; Bergman, D.; Bucher, E.; Deshpande, A.; Forjaz, A.; Getz, M.; Godet, I.; Lyman, M.; Metzcar, J.; Mitchell, J.; Raddatz, A.; Rocha, H. L.; Solorzano, J.; Sundus, A.; Wang, Y.; Gilkes, D. M.; Kagohara, L. T.; Kiemen, A. L.; Thompson, E. D.; Wirtz, D.; Wu, P.-H.; Zaidi, N.; Zheng, L.; Zimmerman, J. W.; Jaffee, E. M.; Chang, Y. H.; Coussens, L.; Gray, J.; Heiser, L. M.; Fertig, E. J.; Macklin, P.
10.1101/2023.09.17.557982 — systems biology — Posted on 2023-09-17
2220 The impact of gestational diabetes on functional capacity of the infant gut microbiome is modest and transient
Chieu, R. V.; Hamilton, K.; Ryan, P. M.; Copeland, J.; Wang, P. W.; Retnakaran, R.; Guttman, D. S.; Parkinson, J.; Hamilton, J.
10.1101/2023.09.14.557457 — systems biology — Posted on 2023-09-17
2221 Using the E. coli Alleleome in Strain Design
Phaneuf, P. V.; Jarczynska, Z. D.; Kandasamy, V.; Chauhan, S. M.; Feist, A. M.; Palsson, B. O.
10.1101/2023.09.17.558058 — synthetic biology — Posted on 2023-09-17
2223 Phosphate starvation regulates cellulose synthesis to modify root growth
Khan, G. A.; Dutta, A.; van de Meene, A.; Frandsen, K. E.; Ogden, M.; Whelan, J.; Persson, S.
10.1101/2023.09.15.557998 — plant biology — Posted on 2023-09-17
2224 Ectopic assembly of an auxin efflux control machinery shifts developmental trajectories
Aliaga Fandino, A. C.; Jelinkova, A.; Marhava, P.; Petrasek, J.; Hardtke, C. S.
10.1101/2023.09.16.558043 — plant biology — Posted on 2023-09-17
2227 Unveiling the phenology and associated floral regulatory pathways of Humulus lupulus L. in subtropical conditions
Gutierrez, R. M.; de Oliveira, R. R.; Ribeiro, T. H. C.; de Oliveira, K. K. P.; Silva, J. V. N.; Alves, T. C.; do Amaral, L. R.; Gomes, M. d. S.; Gomes, M. d. S.; Chalfun-Junior, A.
10.1101/2023.09.15.557988 — plant biology — Posted on 2023-09-17
2229 Gene Deletion of the PACAP/VIP Receptor, VPAC2R, Alters Glycemic Responses During Metabolic and Psychogenic Stress in Adult Female Mice
Kozlova, E. V.; Bishay, A. E.; Denys, M. E.; Chinthirla, B. D.; Valdez, M. C.; Spurgin, K. A.; Krum, J. M.; Basappa, K. R.; Curras-Collazo, M. C.
10.1101/2023.09.14.557790 — physiology — Posted on 2023-09-17
2230 Simultaneous assessment of mechanical and electrical function in Langendorff-perfused ex-vivo mouse heart
Louradour, J.; Ottersberg, R.; Segiser, A.; Olejnik, A.; Martinez-Salazar, B.; Siegrist, M.; Egle, M.; Barbieri, M.; Nimani, S.; Alerni, N.; Döring, Y.; Odening, K. E.; Longnus, S.
10.1101/2023.09.15.557526 — physiology — Posted on 2023-09-17
2232 Epigenetic coordination of transcriptional and translational programs in hypoxia
Watt, K.; Dauber, B.; Szkop, K. J.; Lee, L.; Jovanovic, P.; Chen, S.; Masvidal, L.; Tandoc, K.; Palia, R.; Toposirovic, I.; Larsson, O.; Postovit, L.-M.
10.1101/2023.09.16.558067 — cancer biology — Posted on 2023-09-17
2233 Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6).
Ogier, C.; Charles Solomon, A. M.; Lu, Z.; Recoules, L.; Klochkova, A.; Gabitova-Cornell, L.; Bayarmagnai, B.; Restifo, D.; Surumbayeva, A.; Vendramini-Costa, D. B.; Deneka, A.; Francescone, R.; Lilly, A. C.; Sipman, A.; Gardiner, J. C.; Luong, T.; Franco-Barraza, J.; Ibeme, N.; Cai, Q.; Einarson, M. B.; Nicolas, E.; Efimov, A.; Megill, E.; Snyder, N. W.; Bousquet, C.; Cros, J.; Zhou, Y.; Golemis, E. A.; Gligorijevic, B.; Soboloff, J.; Fuchs, S. Y.; Cukierman, E.; Astsaturov, I.
10.1101/2023.09.15.557802 — cancer biology — Posted on 2023-09-17
2235 A Light sheet fluorescence microscopy and machine learning-based approach to investigate drug and biomarker distribution in whole organs and tumors.
Kumar, N.; Hrobar, P.; Vagenknecht, M.; Soukup, J.; Patterson, N.; Bloomingdale, P.; Freshwater, T.; Bardehle, S.; Peter, R.; Mangadu, R.; Pastuskovas, C. V.; Chabu, C. Y.; Cancilla, M. T.
10.1101/2023.09.16.558068 — cancer biology — Posted on 2023-09-17
2236 Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides
Schofield, J. H.; Longo, J.; Sheldon, R.; Albano, E.; Hawk, M. A.; Murphy, S.; Duong, L.; Rahmy, S.; Lu, X.; Jones, R. G.; Schafer, Z. T.
10.1101/2023.09.14.557799 — cancer biology — Posted on 2023-09-17
2237 FGF19 and its analog Aldafermin cooperate with MYC to induce aggressive hepatocarcinogenesis
Ursic-Bedoya, J.; Desandre, G.; Chavey, C.; Marie, P.; Polizzi, A.; Riviere, B.; Guillou, H.; Assenat, E.; Hibner, U.; Gregoire, D.
10.1101/2023.09.15.557921 — cancer biology — Posted on 2023-09-17
2243 ONeSAMP 3.0: Effective Population Size via SNP Data for One Population Sample
Hong, A.; Cheek, R. G.; Mukherjee, K.; Yooseph, I.; Oliva, M.; Heim, M.; Funk, W. C.; Tallmon, D.; Boucher, C.
10.1101/2023.09.14.557784 — bioinformatics — Posted on 2023-09-17
2245 bamSliceR: cross-cohort variant and allelic bias analysis for rare variants and rare diseases
Huang, Y. P.; Harmon, L. M.; Gardner, E.; Ma, X.; Harsh, J.; Xue, Z.; Wen, H.; Ramos, M.; Davis, S. R.; Triche, T. J.
10.1101/2023.09.15.558026 — bioinformatics — Posted on 2023-09-17
2249 Structure-Activity Relationship Studies of Novel Gut-derived Lantibiotics Against Human Gut Commensals
Zhang, Z. J.; Wu, C.; Dorantes, D.; Pappas, T.; Sundararajan, A.; Lin, H.; Pamer, E. G.; van der Donk, W. A.
10.1101/2023.09.15.557961 — bioengineering — Posted on 2023-09-17
2256 Inferring inter-chromosomal rearrangements and ancestral linkage groups from synteny
Mackintosh, A.; Gonzalez de la Rosa, P. M.; Martin, S. H.; Lohse, K.; Laetsch, D. R.
10.1101/2023.09.17.558111 — evolutionary biology — Posted on 2023-09-17
2259 The Atlantic Forest of South America: spatiotemporal dynamic of remaining vegetation and implications for conservation
Vancine, M. H.; Muylaert, R. L.; Niebuhr, B. B.; Oshima, J. E. d. F.; Tonetti, V.; Bernardo, R.; De Angelo, C.; Rosa, M. R.; Grohmann, C. H.; Ribeiro, M. C.
10.1101/2023.09.16.558076 — ecology — Posted on 2023-09-17
2262 Multifunctional evolution of palm squirrel coat colour and pattern
Nivetha, M.; D'Souza, S.; Shijisha, A.; Ligon, R. A.; Nandini, R.
10.1101/2023.09.15.557893 — ecology — Posted on 2023-09-17
2263 CXCR3-CXCL11 signaling restricts angiogenesis and promotes pericyte recruitment
Goeckel, M. E.; Lee, J.; Levitas, A.; Colijn, S.; Mun, G.; Burton, Z.; Chintalapati, B.; Yin, Y.; Abello, J.; Stratman, A. N.
10.1101/2023.09.16.557842 — developmental biology — Posted on 2023-09-17
2264 Dual role of Toxoplasma gondii ROP5 and ROP18 for NLRP3 inhibition
Murillo-Leon, M.; Bastidas Quintero, A. M.; Singh, S.; Mueller, X.; Gorka, O.; Saller, B.; Arenas Soto, A. F.; Campos, C.; Gomez-Marin, J. E.; Gross, O.; Pfeffer, K.; Howard, J. C.; Taylor, G. A.; Steinfeldt, T.
10.1101/2023.09.17.558105 — microbiology — Posted on 2023-09-17
2266 Exponentially decreasing exposure of antigen generates anti-inflammatory T-cell responses
Esrafili, A.; Kupfer, J.; Thumsi, A.; JAGGARAPU, M.; Suresh, A.; Talitckii, A.; Khodaei, T.; Swaminathan, S.; Mantri, S.; Peet, M.; Acharya, A.
10.1101/2023.09.15.558014 — immunology — Posted on 2023-09-17
2267 Interferon-α promotes neo-antigen formation andpreferential HLA-B-restricted antigen presentation in pancreatic β-cells
Carre, A.; Zhou, Z.; Perez-Hernandez, J.; Samassa, F.; Lekka, C.; Manganaro, A.; Oshima, M.; Liao, H.; Parker, R.; Nicastri, A.; Brandao, B.; Colli, M. L.; Eizirik, D. L.; Göransson, M.; Burgos-Morales, O.; Anderson, A.; Landry, L.; Kobaisi, F.; Scharfmann, R.; Marselli, L.; Marchetti, P.; You, S.; Nakayama, M.; Hadrup, S. R.; Kent, S. C.; Richardson, S. J.; Ternette, N.; Mallone, R.
10.1101/2023.09.15.557918 — immunology — Posted on 2023-09-17
2268 Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis
Joshi, S.; Rodriguez, L. L.; Morosi, L. G.; Amadio, R.; Pachauri, M.; Giacca, M.; Piperno, G. M.; Benvenuti, F.
10.1101/2023.09.14.557776 — immunology — Posted on 2023-09-17
2269 Adolescent Intermittent Ethanol Exposure Alters Adult Exploratory and Affective Behaviors, and Cerebellar Grin2B Expression in C57BL/6J Mice
Healey, K.; Waters, R. C.; Knight, S. G.; Wandling, G. M.; Hall, N. I.; Jones, B. N.; Shobande, M. J.; Melton, J. G.; Pandey, S. C.; Swartzwelder, H. S.; Maldonado-Devincci, A. M.
10.1101/2023.02.13.528396 — neuroscience — Posted on 2023-09-17
2272 Synaptic tagging and capture underlie neuronal co-allocation and temporal association memory in behaving mice
Sakai, Y.; Brizard, B.; Zapata, J.; Zenelaj, X.; Tanti, A.; Camus, V.; Belzung, C.; Surget, A.
10.1101/2023.09.17.558124 — neuroscience — Posted on 2023-09-17
2276 Loss of EIF4G2 Mediates Aggressiveness in Distinct Human Endometrial Cancer Subpopulations with Poorer Survival Outcome in Patients
Meril, S.; Muhlbauer Avni, M.; Lior, C.; Bhalsen, M.; Olender, T.; Savidor, A.; Krausz, J.; Belhanes Peled, H.; Birisi, H.; David, N.; Bialik, S.; Scherz-Shouval, R.; Ben David, Y.; Kimchi, A.
10.1101/2023.09.14.557672 — cancer biology — Posted on 2023-09-17
2277 Reduced glutamate decarboxylase 1 underlies morphine-promoted lung metastasis of triple-negative breast cancer in mice
Chen, S. H.; Shih, C.-H.; Ke, T.-L.; Hsiung, C.-N.; Chen, K.-C.; Huang, Z.-X.; Chuang, T.-H.; Chen, L.-K.; Chen, L.
10.1101/2023.09.14.557710 — cancer biology — Posted on 2023-09-17
2278 Multimodal profiling of chordoma immunity reveals distinct immune contextures
van Oost, S.; Meijer, D. M.; Ijsselsteijn, M. E.; Roelands, J. P.; van den Akker, B. E. W. M.; van der Breggen, R.; Briaire-de Bruijn, I. H.; van der Ploeg, M.; Wijers-Koster, P. M.; Polak, S. B.; Peul, W. C.; van der Wal, R. J. P.; de Miranda, N. F. C. C.; Bovee, J. V. M. G.
10.1101/2023.09.14.557579 — cancer biology — Posted on 2023-09-17
2279 Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment
Strelez, C.; Perez, R.; Chlystek, J. S.; Cherry, C.; Yoon, A. Y.; Haliday, B.; Shah, C.; Ghaffarian, K.; Sun, R. X.; Jiang, H.; Lau, R.; Schatz, A.; Lenz, H.-J.; Katz, J. E.; Mumenthaler, S. M.
10.1101/2023.09.14.557797 — cancer biology — Posted on 2023-09-17
2281 Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in Glioblastoma
Foerster, L. C.; Kaya, O.; Wust, V.; Bekavac, M.; Ziegler, K. C.; Akcay, V.; Stinchcombe, N.; Gesteira Perez, N.; Ma, X.; Sadik, A.; Le, P. U.; Petrecca, K.; Opitz, C.; Liu, H.; Wirtz, C. R.; Anders, S.; Goncalves, A.; Martin-Villalba, A.
10.1101/2023.09.15.557713 — cancer biology — Posted on 2023-09-17
2282 Androgen blockade primes NLRP3 in macrophages to induce tumor phagocytosis
Chaudagar, K. K.; Srikrishnan, R.; Mei, S.; Hirz, T.; Hu, Y.-M.; Argulian, A.; Labadie, B.; Desai, K.; Grimaldo, S.; Kahramangil, D.; Nair, R.; D Souza, S.; Zhou, D.; Li, M.; Doughan, F.; Chen, R.; Shafran, J.; Loyd, M.; Xia, Z.; Sykes, D. B.; Moran, A. E.; Patnaik, A.
10.1101/2023.09.15.557996 — cancer biology — Posted on 2023-09-17
2284 WCRC-25: A novel luminal Invasive Lobular Carcinoma cell line model
Elangovan, A.; Bossart, E. A.; Basudan, A.; Tasdemir, N.; Shah, O. S.; Ding, K.; Meier, C.; Heim, T.; Neumann, C.; Attaran, S.; Brown, L.; Hooda, J.; Miller, L.; Liu, T.; Puhalla, S. L.; Gurda, G.; Lucas, P. C.; McAuliffe, P. F.; Atkinson, J. M.; Lee, A. V.; Oesterreich, S.
10.1101/2023.09.15.558023 — cancer biology — Posted on 2023-09-17
2285 Interferon-Induced Bone Marrow Stromal Antigen 2 (BST2) Is A Functional Tumor-Initiating Cell Marker In Triple-Negative Breast Cancer
Souto, E. P.; Gong, P.; Landua, J. D.; Srinivasan, R. R.; Ganesan, A.; Dobrolecki, L. E.; Purdy, S. C.; Ford, H. L.; Lewis, M. T.
10.1101/2023.09.15.557958 — cancer biology — Posted on 2023-09-17
2293 Improved Protein Model in SPICA Force Field
Yamada, T.; Miyazaki, Y.; Harada, S.; Kumar, A.; Vanni, S.; Shinoda, W.
10.1101/2023.09.15.557852 — biophysics — Posted on 2023-09-17
2298 Enzyme promiscuous profiles for protein sequence and reaction annotation
MohammadiPeyhani, H.; Sveshnikova, A.; Miskovic, L.; Hatzimanikatis, V.
10.1101/2023.09.13.557547 — bioinformatics — Posted on 2023-09-17
2301 Olivar: automated variant aware primer design for multiplex tiled amplicon sequencing of pathogens
Wang, M. X.; Lou, E. G.; Sapoval, N.; Kim, E.; Kalvapalle, P.; Kille, B.; Elworth, R. A. L.; Liu, Y.; Fu, Y.; Stadler, L. B.; Treangen, T. J.
10.1101/2023.02.11.528155 — bioinformatics — Posted on 2023-09-17
2302 Computational Assessment of Aromatase: Unmasking Therapeutic Avenues for Female Hormonal Disorders
Koirala, S. P.; Magar, B. S.; Yadav, A. K.; Regmi, A.; Pokharel, A.; Subedi, S.; Aryal, P.
10.1101/2023.09.13.557603 — bioinformatics — Posted on 2023-09-17
2303 Differentiation and migration of hematopoietic stem and progenitor cells cross multiple tissues
Yu, S.; Li, H.; Wang, X.; Chen, G.; Huang, H.; Hong, N.; Song, Y.-Q.; Zhang, X.; Jin, W.
10.1101/2023.09.15.557856 — genomics — Posted on 2023-09-17
2305 When paleontology meets genomics: complete mitochondrial genomes of two saber-toothed cats' species (Felidae: Machairodontinae)
Rodrigues-Oliveira, I. H.; Batista da Silva, I.; Rodrigues Rocha, R.; Silva Soares, R. A.; Menegidio, F. B.; Garcia, C.; Pasa, R.; Kavalco, K. F.
10.1101/2023.09.14.557696 — genomics — Posted on 2023-09-17
2306 Diverse Plant-Parasitic Nematodes are Selectively Killed by Oxadiazole Thioether Pro-Nematicides
Knox, J.; Burns, A. R.; Cooke, B.; Cammalleri, S. R.; Kitner, M.; Ching, J.; Castelli, J. M. P.; Puumala, E.; Snider, J.; Koury, E.; Collins, J. B.; Andersen, E. C.; Stagljar, I.; Cowen, L.; Lautens, M.; Zasada, I.; Roy, P.
10.1101/2023.09.14.557801 — genetics — Posted on 2023-09-17
2308 Partitioning heritability using single-cell multi-omics identifies a novel macrophage subpopulation conveying genetic risks of coronary artery disease.
Jiang, J.; Hiron, T. K.; Agbaedeng, T.; Malhotra, Y.; Drydale, E. N.; Bancroft, J.; Ng, E.; Reschen, M.; Davison, L. J.; O'Callaghan, C.
10.1101/2023.09.14.557845 — genetics — Posted on 2023-09-17
2309 HLA-Based Banking of Human Induced Pluripotent Stem Cells in Saudi Arabia
Alowaysi, M.; Lehmann, R.; Al-Shehri, M.; Baadheim, M.; Alzahrani, H.; Aboalola, D.; Zia, A.; Malibari, D.; Daghestani, M.; Alghamdi, K.; Haneef, A.; Jawdat, D.; Hakami, F.; Cabrero, D. G.; Tegner, J.; Alsayegh, K.
10.1101/2023.09.16.557826 — genetics — Posted on 2023-09-17
2310 Diverse signatures of convergent evolution in cacti-associated yeasts
Goncalves, C.; Harrison, M.-C.; Steenwyk, J. L.; Opulente, D. A.; LaBella, A. L.; Wolters, J. F.; Zhou, X.; Shen, X.-X.; Groenewald, M.; Hittinger, C. T.; Rokas, A.
10.1101/2023.09.14.557833 — evolutionary biology — Posted on 2023-09-17
2320 3D-intrusions transport active surface microbial assemblages to the dark ocean
Freilich, M. A.; Poirier, C.; Dever, M.; Alou-Font, E.; Allen, J.; Cabornero, A.; Sudek, L.; Choi, C. J.; Ruiz, S.; Pascual, A.; Farrar, J. T.; Johnston, T. M. S.; D'Asaro, E.; Worden, A. Z.; Mahadevan, A.
10.1101/2023.09.14.557835 — ecology — Posted on 2023-09-17
2321 Warnings/Cautions when collecting Brassica diversity along a large climatic gradient
Falentin, C.; Hadj-Arab, H.; Aissiou, F.; Bartoli, C.; Bazan, G.; Boudet, M.; Bousset-Vaslin, L.; Chwikhi, M.; Coriton, O.; Deniot, G.; Ferreira de Carvalho, J.; Gay, L.; Geraci, A.; Glory, P.; Huteau, V.; Ilahy, R.; Ilardi, V.; Jarillo, J. A.; Meglic, V.; Oddo, E.; Pernas, M.; Manuel, P.; Pipan, B.; Rhim, T.; Richer, V.; Rizza, F.; Ronfort, J.; Rousseau-Gueutin, M.; Schicchi, R.; Sinkovic, L.; Taburel, M.; Terzi, V.; Therene, S.; Tiret, M.; Tlili, I.; Werner Badeck, F.; Chevre, A.-M.
10.1101/2023.09.15.557905 — ecology — Posted on 2023-09-17
2322 Automatic vocalisation detection delivers reliable, multi-faceted, and global avian biodiversity monitoring
Sethi, S. S.; Bick, A.; Chen, M.-Y.; Crouzeilles, R.; Hillier, B. V.; Lawson, J.; Lee, C.-Y.; Liu, S.-H.; Parruco, C. H. d. F.; Rosten, C.; Somveille, M.; Tuanmu, M.-N.; Banks-Leite, C.
10.1101/2023.09.14.557670 — ecology — Posted on 2023-09-17
2324 A latent cardiomyocyte regeneration potential in the human heart
Derks, W.; Rode, J.; Collin, S.; Rost, F.; Heinke, P.; Hariharan, A.; Pickel, L.; Simonova, I.; Lazar, E.; Graham, E.; Jashari, R.; Andrae, M.; Jeppsson, A.; Salehpour, M.; Alkass, K.; Druid, H.; Kyriakopoulos, C.; Taleb, I.; Shankar, T.; Selzman, C.; Sadek, H.; Jovinge, S.; Brusch, L.; Frisen, J.; Drakos, S.; Bergmann, O.
10.1101/2023.09.14.557681 — cell biology — Posted on 2023-09-17
2325 Elastin-derived peptides favor type 2 innate lymphoid cells in COPD
Lahire, S.; Fichel, C.; Rubaszewski, O.; Lereverend, C.; Audonnet, S.; Visneux, V.; Perotin, J.-M.; Deslee, G.; Le Jan, S.; Potteaux, S.; Le Naour, R.; Pommier, A.
10.1101/2023.09.13.557567 — immunology — Posted on 2023-09-17
2327 Proteomic adaptations in the kidney reveal orchestration of local and secreted antimicrobial peptides in human pyelonephritis
Borgards, L.; Siebels, B.; Voss, H.; Krisp, C.; Schmitz, J.; Schwarz, L.; Siemes, D.; Spangenberg, P.; Braesen, J. H.; von Vietinghoff, S.; Schluter, H.; Wagenlehner, F.; Engel, D. R.; Shevchuk, O.
10.1101/2023.09.14.557715 — immunology — Posted on 2023-09-17
2330 Multi-omic characterization of antibody-producing CHO cell lines elucidates metabolic reprogramming and nutrient uptake bottlenecks
Gopalakrishnan, S.; Johnson, W.; Gomez, M. A. V.; Icten, E.; Tat, J.; Lay, F.; Diep, J.; Gomez, N.; Stevens, J.; Schlegel, F.; Rolandi, P.; Kontoravdi, C.; Lewis, N. E.
10.1101/2023.09.13.557626 — systems biology — Posted on 2023-09-17
2331 COSMIC-dFBA: A novel multi-scale hybrid framework for bioprocess modeling
Gopalakrishnan, S.; Johnson, W.; Valderrama-Gomez, M. A.; Icten, E.; Tat, J.; Ingram, M.; Shek, C. F.; Chan, P. K.; Schlegel, F.; Rolandi, P.; Kontoravdi, C.; Lewis, N. E.
10.1101/2023.09.13.557646 — systems biology — Posted on 2023-09-17
2338 A HEV ORF2 protein-mediated mechanism of hepatitis E associated kidney disease.
Helmchen, B.; Leblond, A.-L.; Lenggenhager, D.; Jetzer, J.; Ankavay, M.; Helmchen, F.; Yurtsever, H.; Parrotta, R.; Healy, M. E.; Poeschel, A.; Markkanen, E.; Semmo, N.; Ferrie, M.; Cocquerel, L.; Seeger, H.; Hopfer, H.; Muellhaupt, B.; Gouttenoire, J.; Moradpour, D.; Gaspert, A.; Weber, A.
10.1101/2023.09.14.557697 — pathology — Posted on 2023-09-17
2339 BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss.
Shields, M. A.; Metropulos, A. A.; Spaulding, C.; Hirose, T.; Ohno, S.; Pham, T. N.; Munshi, H. G.
10.1101/2023.09.14.557654 — pathology — Posted on 2023-09-17
2340 Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma
Gonzalez-Aponte, M. F.; Damato, A. R.; Trebucq, L. L.; Simon, T.; Cardenas-Garcia, S. P.; Cho, K.; Patti, G. J.; Golombek, D. A.; Chiesa, J. J.; Herzog, E. D.
10.1101/2023.09.13.557630 — cancer biology — Posted on 2023-09-17
2341 Preclinical Synergistic Combination Therapy of Lurbinectedin with Irinotecan and 5-Fluorouracil in Pancreatic Cancer
Tummala, T.; Uruchurtu, A. S. S.; De La Cruz, A.; Huntington, K. E.; George, A.; Liguori, N. R.; Zhang, L.; Zhou, L.; Abbas, A. E.; Azzoli, C. G.; El-Deiry, W. S.
10.1101/2023.09.13.557653 — cancer biology — Posted on 2023-09-17
2342 Cell context-specific Synthetic lethality Prediction and Mechanism Analysis
XIn, Y.; Pu, M.; Tian, K.; Cheng, K.; Wei, L.; Zheng, W.; Peng, G.; Zhou, J.; Zhang, Y.
10.1101/2023.09.13.557545 — cancer biology — Posted on 2023-09-17
2343 Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)
Weichenhan, D.; Riedel, A.; Sollier, E.; Toprak, U. H.; Hey, J.; Breuer, K.; Wierzbinska, J. A.; Touzart, A.; Lutsik, P.; Baehr, M.; Oestlund, A.; Nilsson, C.; Jacobsson, S.; Edler, M.; Waraky, A.; Behrens, Y. L.; Goehring, G.; Schlegelberger, B.; Steinek, C.; Harz, H.; Leonhardt, H.; Dolnik, A.; Reinhardt, D.; Bullinger, L.; Palmqvist, L.; Lipka, D. B.; Plass, C.
10.1101/2023.09.13.557546 — cancer biology — Posted on 2023-09-17
2344 Multiomic single-cell analysis identifies von Willebrand factor and TIM3-expressing BCR-ABL1+ CML stem cells
Nilsson, M. S.; Komic, H.; Gustafsson, J.; Sheybani, Z.; Paul, S.; Rolfson, O.; Hellstrand, K.; Wennström, L.; Martner, A.; Thoren, F. B.
10.1101/2023.09.14.557507 — cancer biology — Posted on 2023-09-17
2346 Computational Assessment of Aromatase: Unmasking Therapeutic Avenues for Female Hormonal Disorders
Pokharel, A.; Aryal, P.; Subedi, S.; Koirala, S. P.; Magar, B. S.; Yadav, A. K.; Regmi, A.
10.1101/2023.09.13.557603 — bioinformatics — Posted on 2023-09-17
2348 Generating Novel Leads for Drug Discovery using LLMs with Logical Feedback
Brahmavar, S. B.; Srinivasan, A.; Dash, T.; Krishnan, S. R.; Vig, L.; Roy, A.; Aduri, R.
10.1101/2023.09.14.557698 — bioinformatics — Posted on 2023-09-17
2350 Using a P. falciparum genetic cross to dissect the relative contributions of pfcrt and plasmepsin II/III to piperaquine response-related traits
Kane, J.; Li, X.; Kumar, S.; Button-Simons, K. A.; Vendrely Brenneman, K.; Dahlhoff, H.; Sievert, M. A. C.; Checkley Needham, L. A.; Shoue, D.; Singh, P. P.; Haile, M. T.; Reyes, A.; Cheeseman, I. H.; Vaughan, A. M.; Anderson, T. J.; Ferdig, M. T.
10.1101/2023.06.06.543862 — genomics — Posted on 2023-09-17
2352 Anisotropic interaction and motion states of locusts in a hopper band
Weinburd, J.; Landsberg, J.; Kravtsova, A.; Lam, S.; Sharma, T.; Simpson, S. J.; Sword, G. A.; Buhl, J.
10.1101/2021.10.29.466390 — animal behavior and cognition — Posted on 2023-09-17
2353 Engineered Immunogens to Elicit Antibodies Against Conserved Coronavirus Epitopes
Kapingidza, B.; Marston, D. J.; Harris, C.; Wrapp, D.; Winters, K.; Mielke, D.; Xiaozhi, L.; Yin, Q.; Foulger, A.; Parks, R.; Barr, M.; Newman, A.; Schaefer, A.; Eaton, A.; Flores, J. M.; Hamer, A.; Cantazaro, N. J.; Mallory, M. L.; Mattocks, M. D.; Berverly, C.; Rhodes, B.; Mansouri, K.; Van Itallie, E.; Vure, P.; Manness, B.; Keyes, T.; Stanfield-Oakley, S.; Woods, C. W.; Petzold, E. A.; Walter, E. B.; Wiehe, K.; Edwards, R. J.; Montefiori, D.; Ferrari, G.; Baric, R.; Cain, D. W.; Saunders, K. O.; Haynes, B. F.; Azoitei, M. L.
10.1101/2023.02.27.530277 — immunology — Posted on 2023-09-17
2354 Quantitative Learning of Cellular Features From Single-cell Transcriptomics Data Facilitates Effective Drug Repurposing
Zhong, J.; Yang, J.; Song, Y.; Zhang, Z.; Wang, C.; Tong, R.; Li, C.; Yu, N.; Zou, L.; Liu, S.; Pu, J.; Lin, W.
10.1101/2023.09.16.558051 — cell biology — Posted on 2023-09-17
2356 An optogenetic method for the controlled release of single molecules
Kashyap, P.; Bertelli, S.; Cao, F.; Kostritskaia, Y.; Blank, F.; Srikanth, N.; Saleppico, R.; Bierhuizen, D.; Lu, X.; Nickel, W.; Campbell, R. E.; Plested, A.; Stauber, T.; Taylor, M. J.; Ewers, H.
10.1101/2023.09.16.557871 — biophysics — Posted on 2023-09-17
2359 Multiplexed CRISPR gene editing in primary human islet cells with Cas9 ribonucleoprotein
Bevacqua, R. J.; Zhao, W.; Merheb, E.; Kim, S. H.; Marson, A.; Gloyn, A. L.; Kim, S. K.
10.1101/2023.09.16.558090 — cell biology — Posted on 2023-09-17
2360 Sperm Cell Painting: A Mechanism Driven Approach for Drug Discovery in Human Spermatozoa
Barratt, C. L. R.; Johnston, Z. C.; Gruber, F. S.; Swedlow, J. R.; Myles, R.; Kane, S. V.; Richardson, A.; Wilson, C.; Martins da Silva, S.; Gilbert, I. H.; Read, K. D.; Day, D. P.
10.1101/2023.09.15.557919 — cell biology — Posted on 2023-09-17
2361 An Ensemble Penalized Regression Method for Multi-ancestry Polygenic Risk Prediction
Zhang, J.; Zhan, J.; Jin, J.; Ma, C.; Zhao, R.; Connell, J. O.; Jiang, Y.; 23andMe Research Team, ; Koelsch, B. L.; Zhang, H.; Chatterjee, N.
10.1101/2023.03.15.532652 — genetics — Posted on 2023-09-17
2363 Hallmark molecular and pathological features of POLG disease are recapitulated in cerebral organoids
Liang, K. X.; Chen, A.; Yangzom, T.; Hong, Y.; Lundberg, C.; Sullivan, G. J.; Tzoulis, C.; Bindoff, L. A.
10.1101/2023.09.16.558087 — cell biology — Posted on 2023-09-17
2364 Early life stress impairs VTA coordination of BLA network and behavioral states
Stone, B. T.; Antonoudiou, P.; Teboul, E.; Scarpa, G.; Weiss, G.; Maguire, J.
10.1101/2023.09.16.558081 — neuroscience — Posted on 2023-09-17
2365 A Neural Speech Decoding Framework Leveraging Deep Learning and Speech Synthesis
Chen, X.; Wang, R.; Khalilian-Gourtani, A.; Yu, L.; Dugan, P.; Friedman, D.; Doyle, W.; Devinsky, O.; Wang, Y.; Flinker, A.
10.1101/2023.09.16.558028 — neuroscience — Posted on 2023-09-17
2367 CD39 expression by regulatory T cells drives CD8+ T cell suppression during experimental Trypanosoma cruzi infection
Furlan, C. L. A.; Boccardo, S.; Rodriguez, C.; Robson, S. C.; Gruppi, A.; Montes, C. L.; Rodriguez, E. V. A.
10.1101/2023.09.14.557792 — immunology — Posted on 2023-09-16
2368 Long-Term Oral Tamoxifen Administration Decreases Brain Derived Neurotrophic Factor in the Hippocampus of Female Long-Evans Rats
Been, L. E.; Halliday, A. R.; Blossom, S. M.; Bien, E. M.; Bernhard, A. G.; Roth, G. E.; Domenech Rosario, K. I.; Pollock, K. B.; Abramenko, P. E.; Behbehani, L. M.; Pascal, G. J.; Kelly, M. E.
10.1101/2023.04.26.538155 — neuroscience — Posted on 2023-09-16
2369 Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior
Al-Kachak, A.; Fulton, S. L.; Di Salvo, G.; Chan, J. C.; Farrelly, L. A.; Lepack, A. E.; Bastle, R. M.; Kong, L.; Cathomas, F.; Newman, E. L.; Menard, C.; Ramakrishnan, A.; Safovich, P.; Lyu, Y.; Covington, H. E.; Shen, L.; Gleason, K.; Tamminga, C. A.; Russo, S. J.; Maze, I.
10.1101/2023.05.04.539464 — neuroscience — Posted on 2023-09-16
2371 Assessing the impact of transcriptomics data analysis pipelines on downstream functional enrichment results
Paton, V.; Gabor, A.; Ramirez Flores, R. O.; Badia-i-Mompel, P.; Tanevski, J.; Garrido-Rodriguez, M.; Saez-Rodriguez, J.
10.1101/2023.09.13.557538 — bioinformatics — Posted on 2023-09-16
2372 Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2
Weeratunga, S.; Gormal, R.; Liu, M.; Eldershaw, D.; Livingstone, E.; Malapaka, A.; Wallis, T.; Bademosi, A.; Jiang, A.; Healy, M.; Meunier, F.; Collins, B.
10.1101/2023.02.20.529329 — biochemistry — Posted on 2023-09-16
2373 The Pex6 N1 domain is required for Pex15 binding and proper assembly with Pex1
Ali, B. A.; Judy, R. M.; Chowdhury, S.; Jacobsen, N. K.; Castanzo, D. T.; Carr, K. L.; Richardson, C. D.; Lander, G. C.; Martin, A.; Gardner, B. M.
10.1101/2023.09.15.557798 — biochemistry — Posted on 2023-09-16
2374 Cryptic splicing mediates genetic and therapeutic perturbation of human gene expression levels
Fair, B. J.; Abad, C. B.; Zhao, J.; Lozano, S.; Reilly, A. K.; Staley, J. P.; Wang, J.; Li, Y. I.
10.1101/2023.09.13.557588 — genomics — Posted on 2023-09-16
2375 Single-cell nascent RNA sequencing using click-chemistry unveils coordinated transcription
Sharp, P. A.; Mahat, D. B.; Tippens, N. D.; Martin-Rufino, J. D.; Waterton, S. K.; Fu, J.; Blatt, S. E.
10.1101/2023.09.15.558015 — genomics — Posted on 2023-09-16
2376 Signatures of transposon-mediated genome inflation, host specialization, and photoentrainment in Entomophthora muscae and allied entomophthoralean fungi
Stajich, J. E.; Lovett, B.; Lee, E.; Macias, A. M.; Hajek, A. E.; de Bivort, B. L.; Kasson, M. T.; De Fine Licht, H. H.; Elya, C.
10.1101/2023.09.13.557621 — genomics — Posted on 2023-09-16
2377 Identification of Genetic and Genomic Influences on Progressive Ethanol Consumption in Diversity Outbred Mice
Smith, M. L.; Sergi, Z.; Mignogna, K. M.; Rodriguez, N. E.; Tatom, Z.; MacLeod, L.; Choi, K.; Philip, V.; Miles, M. F.
10.1101/2023.09.15.554349 — genomics — Posted on 2023-09-16
2382 Global analysis of Poales diversification - parallel evolution in space and time into open and closed habitats
Elliott, T. L.; Spalink, D.; Larridon, I.; Zuntini, A. R.; Escudero, M.; Hackel, J.; Barrett, R. L.; Martin-Bravo, S.; Marquez-Corro, J. I.; Mendoza, C. G.; Mashau, A. C.; Romero-Soler, K. J.; Zhigila, D. A.; Gehrke, B.; Andrino, C. O.; Crayn, D. M.; Vorontsova, M. S.; Forest, F.; Baker, W. J.; Wilson, K. L.; Simpson, D. A.; Muasya, A. M.
10.1101/2023.09.14.557735 — ecology — Posted on 2023-09-16
2384 Molecular and phenotypic blueprint of the hematopoietic compartment reveals proliferation stress as a driver of age-associated human stem cell dysfunctions
Lettera, E.; Scala, S.; Basso-Ricci, L.; Tavella, T.; della Volpe, L.; Lofurno, E.; Kauffmann, K.; Garcia-Prat, L.; Quaranta, P.; Hernandez, R.; Murison, A.; Giannetti, K.; Aguilar-Navarro, A.; Beretta, S.; Conti, A.; Farina, G.; Flores-Figueroa, E.; Conte, P.; Ometti, M.; Xie, S. Z.; Aiuti, A.; Di Micco, R.
10.1101/2023.09.15.557553 — cell biology — Posted on 2023-09-16
2387 U6 snRNA m6A modification is required for accurate and efficient cis- and trans-splicing of C. elegans mRNAs
Shen, A.; Hencel, K.; Parker, M. T.; Scott, R.; Skukan, R.; Adesina, A. S.; Metheringham, C. L.; Miska, E. A.; Nam, Y.; Haerty, W.; Simpson, G. G.; Akay, A.
10.1101/2023.09.16.558044 — molecular biology — Posted on 2023-09-16
2388 Adenine methylation is very scarce in the drosophila genome and not erased by the Ten Eleven Translocation dioxygenase.
Boulet, M.; Gilbert, G.; Renaud, Y.; Schmidt-Dengler, M.; Plantie, E.; Bertrand, R.; Nan, X.; Jurkowski, T.; Helm, M.; Vandel, L.; Waltzer, L.
10.1101/2023.09.15.557947 — molecular biology — Posted on 2023-09-16
2390 Robust and scalable single-molecule protein sequencing with fluorosequencing
Mapes, J. H.; Stover, J.; Stout, H. D.; Folsom, T. M.; Babcock, E.; Loudwig, S.; Martin, C.; Austin, M.; Howdieshell, C. J.; Simpson, Z. B.; Blom, T.; Weaver, D.; Winkler, D.; Velden, K. V.; Ossareh, P. M.; Beierle, J. M.; Somekh, T.; Bardo, A. M.; Anslyn, E. V.; Marcotte, E. M.; Swaminathan, J.
10.1101/2023.09.15.558007 — molecular biology — Posted on 2023-09-16
2392 Effects of Polyphosphate metabolism Mutations on Biofilm, Capsule Formation and Virulence Traits in Hypervirulent ST23 Klebsiella pneumoniae SGH10
Rojas, D.; Marcoleta, A. E.; Galvez-Silva, M.; Varas, M. A.; Diaz, M.; Hernandez, M.; Vargas, C.; Nourdin, G.; Koch, E.; Saldivia, P.; Vielma, J.; Gan, Y.-H.; Chen, Y.; Guiliani, N.; Chavez, F. P.
10.1101/2023.09.15.557991 — microbiology — Posted on 2023-09-16
2394 Poly-basic peptides and polymers as new drug candidate against Plasmodium falciparum
Sivakumar, R.; Floyd, K.; Jessey, E.; Kim Kim, J.; Bayguinov, P.; Fitzpatrick, J. A. J.; Goldfarb, D.; Jovanovic, M.; Tripathi, A.; Djuranovic, S.; Pavlovic Djuranovic, S.
10.1101/2023.09.16.558069 — microbiology — Posted on 2023-09-16
2395 Tailpiece Heating device for effective prevention of biofilm growth in sink plumbing
Kotay, S. M.; Guilford, W. H.; Pettygrove, B. A.; Komisarcik, A. J.; Hughes, S. A.; Mathers, A. J.
10.1101/2023.09.15.558019 — microbiology — Posted on 2023-09-16
2396 The TcdE holin drives toxin secretion and virulence in Clostridioides difficile.
DiBenedetto, N. V.; Oberkampf, M.; Cersosimo, L.; Yeliseyev, V.; Bry, L.; Peltier, J.; Dupuy, B.
10.1101/2023.09.16.558055 — microbiology — Posted on 2023-09-16
2397 Mapping the interaction sites of Influenza A viruses and human complement Factor H
Rabeeah, I.; Billington, E.; Nal, B.; Sadeyen, J.-R.; Pathan, A.; Iqbal, M.; Temperton, N. J.; Zipfel, P. J.; Skerka, C.; Kishore, U.; Shelton, H.
10.1101/2023.09.15.557969 — immunology — Posted on 2023-09-16
2398 Plasma cell differentiation, antibody quality, and initial germinal center B cell population depend on glucose influx rate
Brookens, S. K.; Cho, S. H.; Paik, Y.; Meyer, K.; Raybuck, A. L.; Park, C.; Greenwood, D. L.; Rathmell, J. C.; Boothby, M. R.
10.1101/2023.09.13.557599 — immunology — Posted on 2023-09-16
2400 Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis
Alvarez-Martinez, M.; Cox, L. S.; Pearson, C. F.; Branchett, W. J.; Chakravarty, P.; Wu, X.; Slawinski, H.; Al Dibouni, A.; Samelis, V.; Gabrysova, L.; Priestnall, S. L.; Suarez-Bonnet, A.; Mikolajczak, A.; Briscoe, J.; Powrie, F.; O'Garra, A.
10.1101/2023.09.14.557705 — immunology — Posted on 2023-09-16
2401 γδ T cells impair airway macrophage differentiation in lung adenocarcinoma
Raffo-Iraolagoitia, X. L.; McFarlane, A. J.; Kruspig, B.; Fercoq, F.; Secklehner, J.; De Donatis, M.; Mackey, J. B. G.; Wiesheu, R.; Laing, S.; Hsieh, Y.-C.; Shaw, R.; Corbyn, R.; Nixon, C.; Miller, C.; Kirschner, K.; Bain, C. C.; Murphy, D. J.; Coffelt, S. B.; Carlin, L. M.
10.1101/2023.09.14.557344 — immunology — Posted on 2023-09-16
2405 A cell-free transcription-translation pipeline for recreating methylation patterns boosts DNA transformation in bacteria
Vento, J. M.; Durmusoglu, D.; Li, T.; Sullivan, S. M.; Ttofali, F.; van Schaik, J.; Yu, Y.; Barquist, L.; Crook, N.; Beisel, C. L.
10.1101/2023.09.16.557782 — synthetic biology — Posted on 2023-09-16
2406 ERF and WRKY transcription factors regulate IDA and abscission timing in Arabidopsis.
Galindo-Trigo, S.; Bagman, A.-M.; Ishida, T.; Sawa, S.; Brady, S. M.; Butenko, M. A.
10.1101/2023.09.12.557497 — plant biology — Posted on 2023-09-16
2408 Cell competition promotes metastatic intestinal cancer through a multistage process
Krotenberg Garcia, A.; Ledesma-Terron, M.; Vriend, J.; van Luyk, M. E.; Suijkerbuijk, S. J.
10.1101/2023.09.14.557359 — cancer biology — Posted on 2023-09-16
2409 Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer
Alexander, K. A.; Yu, R.; Skuli, N.; Coffey, N. J.; Nguyen, S.; Faunce, C.; Huang, H.; Dardani, I.; Good, A. L.; Lim, J.; Li, C.; Biddle, N.; Joyce, E. F.; Raj, A.; Lee, D.; Keith, B.; Simon, M. C.; Berger, S. L.
10.1101/2023.09.14.557228 — cancer biology — Posted on 2023-09-16
2410 MTOR as a selectable genomic harbor for CRISPR-engineered CAR-T cell therapy
Levesque, S.; Carleton, G.; Duque, V.; Goupil, C.; Fiset, J.-P.; Villeneuve, S.; Normandeau, E.; Morin, G.; Dumont, N.; Laganiere, J.; Boyle, B.; Lum, J. J.; Doyon, Y.
10.1101/2023.09.14.557485 — cancer biology — Posted on 2023-09-16
2411 A Novel Aberrantly Spliced Gain-of-Function NT5C2 Isoform Contributes to Thiopurine Resistance in Acute Lymphoblastic Leukemia
Diz, M. T.; Reglero, C.; Falkenstein, C. D.; Castro, A.; Hayer, K. E.; Radens, C.; Quesnel-Vallieres, M.; Ang, Z.; Sehgal, P.; Li, M. M.; Barash, Y.; Tasian, S. K.; Ferrando, A.; Thomas-Tikhonenko, A.
10.1101/2023.09.14.557413 — cancer biology — Posted on 2023-09-16
2415 eDAVE - extension of GDC Data Analysis, Visualization, and Exploration Tools
Binkowski, J.; Taryma-Lesniak, O.; Sokolowska, K. E.; Przybylowicz, P. K.; Staszewski, M.; Wojdacz, T. K.
10.1101/2023.09.13.557577 — bioinformatics — Posted on 2023-09-16
2417 Targeted decontamination of sequencing data with CLEAN
Lataretu, M.; Krautwurst, S.; Viehweger, A.; Brandt, C.; Hölzer, M.
10.1101/2023.08.05.552089 — bioinformatics — Posted on 2023-09-16
2419 Sound-mediated nucleation and growth of amyloid fibrils
Kozell, A.; Solomonov, A.; Benyamin, D.; Greenblatt, H. M.; Levy, Y.; Rosenhek-Goldian, I.; Raviv, U.; Shimanovich, U.
10.1101/2023.09.16.558053 — biochemistry — Posted on 2023-09-16
2421 Unique territorial and sub-chromosomal organization revealed in the holocentric moth Bombyx mori
Gil, J.; Rosin, L. F.; Navarrete, E.; Chowdhury, N.; Abraham, S.; Cornilleau, G.; Lei, E. P.; Mozziconacci, J.; Mirny, L. A.; Muller, H.; Drinnenberg, I. A.
10.1101/2023.09.14.557757 — genomics — Posted on 2023-09-16
2423 Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
Riepe, C.; Wachalska, M.; Deol, K. K.; Amaya, A. K.; Porteus, M. H.; Olzmann, J.; Kopito, R. R.
10.1101/2023.09.15.556420 — cell biology — Posted on 2023-09-16
2424 CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia
Dinakaran, S.; Zhao, H.; Tang, Y.; Wang, Z.; Ruiz, S.; Nomura-Kitabayashi, A.; Blanc, L.; Faughnan, M. E.; Marambaud, P.
10.1101/2023.09.15.554413 — cell biology — Posted on 2023-09-16
2425 ZeptoCTC - Sensitive Protein Analysis of True Single Cell Lysates using Reverse Phase Protein Arrays (RPPA)
Rivandi, M.; Franken, A.; Yang, L.; Abramova, A.; Stamm, N.; Eberhardt, J.; Gierke, B.; Beer, M.; Fehm, T.; Niederacher, D.; Pawlak, M.; Neubauer, H.
10.1101/2023.09.16.558042 — molecular biology — Posted on 2023-09-16
2430 Comparison of image registration techniques in functional ultrasound imaging
Zhong, S.; Agyeman, K.; Syed, S.; Tobing, R. L.; Choi, W.; Liu, C.; Lee, D. J.; Christopoulos, V.
10.1101/2023.09.15.557999 — neuroscience — Posted on 2023-09-16
2436 A robust knock-in approach using a minimal promoter and a minicircle
Keating, M.; Hagle, R.; Osorio-Mendez, D.; Rodriguez, A.; Almutawa, S.; Kang, J.
10.1101/2023.09.15.558008 — developmental biology — Posted on 2023-09-16
2438 Driver lines for studying associative learning in Drosophila
Shuai, Y.; Sammons, M.; Sterne, G. R.; Hibbard, K.; Yang, H.; Yang, C.-P.; Managan, C.; Siwanowicz, I.; Lee, T.; Rubin, G. M.; Turner, G. C.; Aso, Y.
10.1101/2023.09.15.557808 — neuroscience — Posted on 2023-09-16
2441 The association between cortical gyrification and sleep in adolescents and young adults.
Lima Santos, J. P.; Hayes, R.; Franzen, P. L.; Goldstein, T. R.; Hasler, B. P.; Buysse, D. J.; Siegle, G. J.; Dahl, R. E.; Forbes, E. E.; Ladouceur, C. D.; McMakin, D. L.; Ryan, N. D.; Silk, J. S.; Jalbrzikowski, M.; Soehner, A.
10.1101/2023.09.15.557966 — neuroscience — Posted on 2023-09-16
2442 Cone-opponent ganglion cells in the primate fovea tuned to non-cardinal color directions
Godat, T.; Kohout, K.; Parkins, K.; Yang, Q.; McGregor, J. E.; Merigan, W. H.; Williams, D. R.; Patterson, S. S.
10.1101/2023.09.15.557995 — neuroscience — Posted on 2023-09-16
2443 Interaction between task-evoked and spontaneous brain activities: Insights from two event-related fMRI studies
Nayak, S.; Hojjati, S. H.; Ozoria-Blake, S.; Feiz, F.; Shteingart, J.; Guerrero, A. F.; Razlighi, Q. R.
10.1101/2023.09.16.557985 — neuroscience — Posted on 2023-09-16
2444 The impact of Parkinson's disease on striatal network connectivity and cortico-striatal drive: an in-silico study
Carannante, I.; Scolamiero, M.; Hjorth, J.; Kozlov, A.; Bekkouche, B.; Guo, L.; Kumar, A.; Chacholski, W.; Hellgren Kotaleski, J.
10.1101/2023.09.15.557977 — neuroscience — Posted on 2023-09-16
2445 Effects of circadian disruption via dim light at night in C57BL6/J mice on recoveryafter spinal cord injury
Aldrich, J. C.; Scheinfeld, A. R.; Lee, S. E.; Mahach, K. M.; Van de Veire, B. C.; Fonken, L. K.; Gaudet, A. D.
10.1101/2023.09.15.557980 — neuroscience — Posted on 2023-09-16
2449 Enhancing KCC2 function reduces interictal activity and prevents seizures in mesial temporal lobe epilepsy
Donneger, F.; Zanin, A.; Besson, J.; Kadiri, Y.; Pagan, C.; David, N.; Russeau, M.; Bielle, F.; Devaux, B.; Mathon, B.; Navarro, V.; Chassoux, F.; Poncer, J. C.
10.1101/2023.09.16.557753 — neuroscience — Posted on 2023-09-16
2453 Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer's disease
Hori, A.; Ai, T.; Hato, T.; Inaba, H.; Tanaka, K.; Okamoto, M.; Horiuchi, Y.; Paran, F. J.; Tabe, Y.; Rosales, C.; Akamatsu, W.; Murayama, T.; Sakurai, T.; Miida, T.
10.1101/2023.09.15.558029 — neuroscience — Posted on 2023-09-16
2454 Intragenic DNA inversions expand bacterial coding capacity
Chanin, R. B.; West, P. T.; Park, R. M.; Wirbel, J.; Green, G. Z. M.; Miklos, A. M.; Gill, M. O.; Hickey, A. S.; Brooks, E. F.; Bhatt, A. S.
10.1101/2023.03.11.532203 — microbiology — Posted on 2023-09-16
2459 ULK1-dependent phosphorylation of PKM2 antagonizes O-GlcNAcylation and inhibits the Warburg effect in breast cancer
Zhou, Z.; Zheng, X.; Zhao, J.; Yuan, A.; Shao, G.; Peng, B.; Dong, M.-Q.; Xu, Q.; Xu, X.; Li, J.
10.1101/2023.09.14.557850 — biochemistry — Posted on 2023-09-16
2461 Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4
Ravala, S. K.; Adame-Garcia, S. R.; Li, S.; Chen, C.-L.; Cianfrocco, M. A.; Gutkind, J. S.; Cash, J. N.; Tesmer, J. J. G.
10.1101/2023.09.15.557836 — biochemistry — Posted on 2023-09-16
2462 DNA-dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes
Kovacs, Z. J.; Harami, G. M.; Palinkas, J.; Kuljanishvili, N.; Hegedüs, J.; Harami-Papp, H.; Mahmudova, L.; Khamisi, L.; Szakacs, G.; Kovacs, M.
10.1101/2023.09.15.557979 — biochemistry — Posted on 2023-09-16
2469 Genomic consequences of isolation and inbreeding in an island dingo population
Leon-Apodaca, A. V.; Kumar, M.; del Castillo, A.; Conroy, G. C.; Lamont, R. W.; Ogbourne, S.; Cairns, K. M.; Borburgh, L.; Behrendorff, L.; Subramanian, S.; Szpiech, Z. A.
10.1101/2023.09.15.557950 — evolutionary biology — Posted on 2023-09-15
2471 A cerebellar disinhibitory circuit supports synaptic plasticity
Park, C.; Gim, J.; Bahn, S.; Kim, G. H.; Im, Y.; Lee, S.-H.; Lee, K.; Kim, M.-S.; Lee, K. J.; Kim, J. S.
10.1101/2023.09.15.557147 — neuroscience — Posted on 2023-09-15
2472 Application of Machine Learning and Virtual Reality for Volumetric Analysis of Arterial Lesions
Cartaya, A. E.; Maiocchi, S. L.; Buglak, N.; Torzone, S. K.; Messinger, G. M.; Bahnson, E. M.
10.1101/2022.12.23.521811 — physiology — Posted on 2023-09-15
2474 Material Properties of Nonpregnant and Pregnant Human Uterine Layers
Fodera, D. M.; Russell, S. R.; Lund-Jackson, J. L.; Fang, S.; Vink, J.-S. Y.; Oyen, M. L.; Myers, K. M.
10.1101/2023.08.07.551726 — bioengineering — Posted on 2023-09-15
2478 Pupil size reveals arousal level dynamics in human sleep
Carro-Dominguez, M.; Huwiler, S.; Oberlin, S.; Oesch, T. L.; Badii, G.; Lüthi, A.; Wenderoth, N.; Meissner, S. N.; Lustenberger, C.
10.1101/2023.07.19.549720 — neuroscience — Posted on 2023-09-15
2479 The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation
Elorette, C.; Fujimoto, A.; Stoll, F. M.; Fujimoto, S. H.; Fleysher, L.; Bienkowska, N.; Russ, B. E.; Rudebeck, P.
10.1101/2023.06.21.545778 — neuroscience — Posted on 2023-09-15
2482 Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior
Al-Kachak, A.; Fulton, S. L.; Di Salvo, G.; Chan, J. C.; Farrelly, L. A.; Lepack, A. E.; Bastle, R. M.; Kong, L.; Cathomas, F.; Newman, E. L.; Menard, C.; Ramakrishnan, A.; Safovich, P.; Lyu, Y.; Covington, H. E.; Shen, L.; Gleason, K.; Tamminga, C. A.; Russo, S. J.; Maze, I.
10.1101/2023.05.04.539464 — neuroscience — Posted on 2023-09-15
2485 A new experimental evidence-weighted signaling pathway resource in FlyBase.
Attrill, H.; Antonazzo, G.; Goodman, J. L.; Thurmond, J.; Strelets, V. B.; Brown, N. H.
10.1101/2023.08.10.552786 — bioinformatics — Posted on 2023-09-15
2486 Mechanisms of action and synergies of a novel lipid IVA biosynthesis inhibitor
Holden, E. R.; Yasir, M.; Turner, A. K.; Webber, M. A.; Charles, I. G.; Siegwart, E.; Raynham, T.; Mistry, A.; George, J.; Gilmour, M.
10.1101/2023.09.15.557861 — molecular biology — Posted on 2023-09-15
2487 Multi-omic profiling of pathogen-stimulated primary immune cells
Salz, R.; Vorsteveld, E. E.; van der Made, C. I.; Kersten, S.; Stemerdink, M.; Hsieh, T.; Mhlanga, M.; Netea, M.; Volders, P.-J.; Hoischen, A.; 't Hoen, P. A. C.
10.1101/2023.09.13.557514 — immunology — Posted on 2023-09-15
2492 Structural and mechanistic insights into human choline transport
Weng, T.-H.; Claveras Cabezudo, A.; Jösting, W.; Bazzone, A.; Welsch, S.; Gursu, G.; Hummer, G.; Wu, D.; Safarian, S.
10.1101/2023.09.15.557925 — biophysics — Posted on 2023-09-15
2494 Deep learning versus geometric morphometrics for archaeobotanical domestication study and subspecific identification
Bonhomme, V.; Bouby, L.; Claude, J.; Dham, C.; Gros-Balthazard, M.; Ivorra, S.; Jeanty, A.; Pagnoux, C.; Pastor, T.; Terral, J.-F.; Evin, A.
10.1101/2023.09.15.557939 — bioinformatics — Posted on 2023-09-15
2497 CRISPR-Cas9 Extracellular Vesicles for Treating Hearing Loss
Pan, X.; Huang, P.; Ali, S.; Hutchinson, T. E.; Erwin, N.; Greenberg, Z. F.; Ding, Z.; Li, Y.; Fernadez, N. E.; Staecker, H.; He, M.
10.1101/2023.09.14.557853 — bioengineering — Posted on 2023-09-15
2500 Behavioral and transcriptomic analyses of mecp2 function in zebrafish
Santistevan, N. J.; Ford, C. T.; Gilsdorf, C. S.; Grinblat, Y. T.
10.1101/2023.09.13.557635 — genetics — Posted on 2023-09-15
2501 Characterization of Dr20/22: Molecular Insights and Antibody Response in Naturally Infected Dogs with Dirofilaria repens
Pekacz, M.; Basalaj, K.; Mlocicki, D.; Kamaszewski, M.; Carreton, E.; Morchon, R.; Wisniewski, M.; Zawistowska-Deniziak, A.
10.1101/2023.09.15.557890 — molecular biology — Posted on 2023-09-15
2502 Leishmania Ribosomal Protein (RP) paralogous genes compensate each others expression maintaining protein native levels
Borges, F. d. S.; Quilles Junior, J. C.; Lorenzon, L. B.; Espada, C. R.; Freitas-Castro, F.; Defina, T. P. A.; Holetz, F. B.; Cruz, A. K.
10.1101/2023.09.15.557908 — molecular biology — Posted on 2023-09-15
2503 Endothelial-fibroblast interactions during Scarb1 accelerate heart failure
Katsuki, T.; Kusumoto, D.; Akiba, Y.; Kimura, M.; Komuro, J.; Nakamura, T.; Hashimoto, H.; Kuoka, T.; Suzuki, Y.; Kubota, Y.; Fukuda, K.; Yuasa, S.; Ieda, M.
10.1101/2023.09.15.557661 — molecular biology — Posted on 2023-09-15
2504 Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype
Marichannegowda, M. H.; Setua, S.; Bose, M.; Sanders-Buell, E.; King, D.; Zemil, M.; Wieczorek, L.; Diaz-Mendez, F.; Chomont, N.; Thomas, R.; Francisco, L.; Eller, L. A.; Polonis, V. R.; Tovanabutra, S.; Tagaya, Y.; Michael, N. L.; Robb, M. L.; Song, H.
10.1101/2023.09.15.557832 — microbiology — Posted on 2023-09-15
2505 Multiple evolutionary pathways lead to vancomycin resistance in Clostridioides difficile
Buddle, J. E.; Wright, R. C. T.; Turner, C. E.; Chaudhuri, R. R.; Brockhurst, M. A.; Fagan, R. P.
10.1101/2023.09.15.557922 — microbiology — Posted on 2023-09-15
2507 Unveiling IRF4-steered regulation of context-dependent effector programs in Th17 and Treg cells
Gabele, A.; Sprang, M.; Cihan, M.; Dietzen, S.; Klein, M.; Harms, G.; Ziesmann, T.; Pape, K.; Wasser, B.; Gomez-Zepeda, D.; Braband, K.; Delacher, M.; Lemmermann, N.; Bittner, S.; Andrade-Navarro, M. A.; Tenzer, S.; Bopp, T.; Distler, U.
10.1101/2023.09.14.557376 — immunology — Posted on 2023-09-15
2509 State dependent constraints on claustrocortical communication and function
Marriott, B. A.; Do, A. D.; Portet, C.; Thellier, F.; Goutagny, R.; Jackson, J.
10.1101/2023.09.15.557951 — neuroscience — Posted on 2023-09-15
2511 Developmental priming of cancer susceptibility
Panzeri, I.; Fagnocchi, L.; Apostle, S.; Tompkins, M.; Wolfrum, E.; Madaj, Z.; Hostetter, G.; Liu, Y.; Schaefer, K.; Yang, C.-H.; Bergsma, A.; Drougard, A.; Dror, E.; PERMUTE, ; Chandler, D.; Schramek, D.; Triche, T. J.; Pospisilik, J. A.
10.1101/2023.09.12.557446 — cancer biology — Posted on 2023-09-15
2516 SACNet: A Multiscale Diffeomorphic Convolutional Registration Network with Prior Neuroanatomical Constraints for Flexible Susceptibility Artifact Correction in Echo Planar Imaging
Zeng, Z.; Zhang, J.; Liang, X.; Sun, L.; Zhang, Y.; Men, W.; Wang, Y.; Chen, R.; Zhang, H.; Tan, S.; Gao, J.-H.; Qin, S.; Tong, Q.; He, H.; Tao, S.; Dong, Q.; He, Y.; Zhao, T.
10.1101/2023.09.15.557874 — neuroscience — Posted on 2023-09-15
2518 Cardiorespiratory fitness is associated with neuroelectric activity complexity in children with overweight or obesity
Minguillon, J.; Perez-Valero, E.; Lopez-Gordo, M. A.; Esteban-Cornejo, I.; Ortega, F. B.; Mora-Gonzalez, J.
10.1101/2023.09.15.557885 — neuroscience — Posted on 2023-09-15
2520 Cerebellar circuits for disinhibition and synchronous inhibition
Lackey, E.; Moreira, L.; Norton, A.; Hemelt, M.; Osorno, T.; Nguyen, T.; Macosko, E.; Lee, W.-C. A.; Hull, C. A.; regehr, w.
10.1101/2023.09.15.557934 — neuroscience — Posted on 2023-09-15
2522 Sensory Adaptations: Insights into the Vomeronasal System of the Iberian Wolf
ORTIZ-LEAL, I.; TORRES, M. V.; BARREIRO-VAZQUEZ, J.-D.; LOPEZ-BECEIRO, A.; FIDALGO, L.; Sanchez-Quinteiro, P.
10.1101/2023.09.14.557816 — neuroscience — Posted on 2023-09-15
2523 Single-cell resolution functional networks during sleep aresegregated into spatially intermixed modules
Kiyooka, D.; Oomoto, I.; Kitazono, J.; Kobayashi, M.; Matsubara, C.; Kobayashi, K.; Murayama, M.; Oizumi, M.
10.1101/2023.09.14.557838 — neuroscience — Posted on 2023-09-15
2525 Transcriptomic signatures of Abeta- and tau-induced neuronal dysfunction reveal inflammatory processes at the core of Alzheimer's disease pathophysiology
Sanchez-Rodriguez, L. M.; Khan, A.; Adewale, Q.; Bezgin, G.; Therriault, J.; Fernandez-Arias, J.; Servaes, S.; Rahmouni, N.; Tissot, C.; Stevenson, J.; Jiang, H.; Chai, X. J.; Carbonell, F.; Rosa-Neto, P.; Iturria-Medina, Y.
10.1101/2023.09.15.557737 — neuroscience — Posted on 2023-09-15
2532 Developmental Mouse Brain Common Coordinate Framework
Kronman, F. A.; Liwang, J. K.; Betty, R.; Vanselow, D. J.; Wu, Y.-t.; Tustison, N. J.; Bhandiwad, A.; Manjila, S. B.; Minteer, J. A.; Shin, D.; Lee, C. H.; Patil, R.; Duda, J. T.; Puelles, L.; Gee, J. C.; Zhang, J.; Ng, L.; Kim, Y.
10.1101/2023.09.14.557789 — neuroscience — Posted on 2023-09-15
2533 maskNMF: A denoise-sparsen-detect approach for extracting neural signals from dense imaging data
Pasarkar, A. P.; Kinsella, I.; Zhou, P.; Wu, M. M.; Pan, D.; Fan, J. L.; Wang, Z.; Abdeladim, L.; Peterka, D. S.; Adesnik, H.; Ji, N.; Paninski, L.
10.1101/2023.09.14.557777 — neuroscience — Posted on 2023-09-15
2536 Low-latency extracellular spike assignment for high-density electrodes at single-neuron resolution
Lai, C.; Kim, D.; Lustig, B.; Tanaka, S.; Barbartis, B.; Narayan, L.; Colonell, J.; Paulsen, O.; Lee, A. K.; Harris, T. D.
10.1101/2023.09.14.557854 — neuroscience — Posted on 2023-09-15
2537 Microvascular Specificity of Spin Echo BOLD fMRI: Impact of EPI Echo Train Length
van Horen, T. W. P.; Siero, J. C. W.; Bhogal, A. A.; Petridou, N.; Baez-Yanez, M. G.
10.1101/2023.09.15.557938 — neuroscience — Posted on 2023-09-15
2539 Social Determinants modulate NK cell activity via obesity, LDL, and DUSP1 signaling
Baumer, Y.; Singh, K.; Baez, A. S.; Gutierrez-Huerta, C. A.; Cheng, L.; Igboko, M.; Turner, B. S.; Yeboah, J. A.; Reger, R. N.; Ortiz-Whittingham, L. R.; Bleck, C. K.; Mitchell, V. M.; Collins, B. S.; Pirooznia, M.; Dagur, P. K.; Allan, D. S.; Schwartz, D. M.; Childs, R. W.; Powell-Wiley, T. M.
10.1101/2023.09.12.556825 — immunology — Posted on 2023-09-15
2540 Intracellular K+ limits T cell exhaustion and preserves antitumor function
Collier, C.; Wucherer, K.; Mcwhorter, M.; Jenkins, C.; Bartlett, A.; Roychoudhuri, R.; Eil, R.
10.1101/2023.09.13.556997 — immunology — Posted on 2023-09-15
2541 CCR2-targeting pepducins reduce T cell-nociceptor interaction driving bone cancer pain
Midavaine, E.; Brouillette, R. R.; Theberge, E.; Mona, C. E.; Kashem, S. W.; Cote, J.; Zeugin, V.; Besserer-Offroy, E.; Longpre, J.-M.; Marsault, E.; Sarret, P.
10.1101/2023.09.15.556569 — neuroscience — Posted on 2023-09-15
2542 Stem nodulation: diversity and occurrence in Aeschynomene and Sesbania legumes from wetlands of Madagascar
Manantsoa, F. F.; Rakotoarisoa, M. F.; Chaintreuil, C.; Razakatiana, A. T.; Gressent, F.; Pervent, M.; Bourge, M.; Andrianandrasana, M. D.; Nouwen, N.; Randriambanona, H.; Ramanankierana, H.; Arrighi, J.-F.
10.1101/2023.09.12.557367 — plant biology — Posted on 2023-09-15
2543 Synergistic effects of combing proton- or X-irradiation with anti-PDL1 immunotherapy in two murine oral cancers
Rykkelid, A. M.; Sinha, P. M.; Folefac, C. A.; Horsman, M. R.; Sorensen, B. S.; Soland, T. M.; Schreurs, O. J. F.; Malinen, E.; Edin, N. F. J.
10.1101/2023.09.13.557140 — cancer biology — Posted on 2023-09-15
2544 Cooperativity and induced oligomerisation control the interaction of SARS- CoV-2 with its cellular receptor and patient-derived antibodies
Asor, R.; Olerinyova, A.; Burnap, S. A.; Kushwah, M. S.; Soltermann, F.; Rudden, L. P.; Hensen, M.; Vasiljevic, S.; Brun, J.; Hill, M.; Chang, L.; Dejnirattisai, W.; Supasa, P.; Mongkolsapaya, J.; Zhou, D.; Stuart, D. I.; Screaton, G.; Degiacomi, M.; Zitzmann, N.; Benesch, J. L.; Struwe, W. B.; Kukura, P.
10.1101/2023.09.14.557399 — biophysics — Posted on 2023-09-15
2545 Reentrant DNA shells tune polyphosphate condensate size
Chawla, R.; Tom, J. K. A.; Boyd, T.; Grotjahn, D. A.; Park, D.; Deniz, A. A.; Racki, L. R.
10.1101/2023.09.13.557044 — biophysics — Posted on 2023-09-15
2546 Leveraging Machine Learning to Uncover the Hidden Links between Trusting Behavior and Biological Markers
Cao, Z.; Setoyama, D.; Monica-Natsumi, D.; Matsushima, T.; Yada, Y.; Watabe, M.; Hikida, T.; Kato, T. A.; Honda, N.
10.1101/2023.09.12.557384 — bioinformatics — Posted on 2023-09-15
2551 Evolution of sex differences in cooperation:the role of trade-offs with dispersal
Capilla-Lasheras, P.; Bircher, N.; Brown, A.; Harrison, X.; Reed, T. E.; York, J.; Cram, D.; Rutz, C.; Walker, L.; Naguib, M.; Young, A.
10.1101/2023.09.13.557370 — evolutionary biology — Posted on 2023-09-15
2552 Biofluorescence reveals hidden patterns in chitons with implications to visual ecology.
Grimaldi, G. G.; Guidi, R. d. S.; Jardim, J. A.; Hirota, M.; Pessoa, D. M. d. A.; Horta, P. A.
10.1101/2023.09.13.557364 — ecology — Posted on 2023-09-15
2554 A novel vaccine strategy using quick and easy conversion of bacterial pathogens to unnatural amino acid-auxotrophic suicide derivatives
Nagasawa, Y.; Nakayama, M.; Kato, Y.; Ogawa, Y.; Aribam, S. D.; Tsugami, Y.; Iwata, T.; Mikami, O.; Sugiyama, A.; Onishi, M.; Hayashi, T.; Eguchi, M.
10.1101/2023.09.14.557119 — microbiology — Posted on 2023-09-15
2555 Enhanced neutralization of SARS-CoV-2 XBB sub-lineages and BA.2.86 by a tetravalent COVID-19 vaccine booster
Wang, X.; Jiang, S.; Ma, W.; Li, X.; Wei, K.; Xie, F.; Zhao, C.; Zhao, X.; Li, C.; Qiao, R.; Cui, Y.; Chen, Y.; Li, J.; Cai, G.; Liu, C.; Hu, Z.; Zhang, W.; Li, M.; Zhang, Y.; Wang, P.
10.1101/2023.09.14.557682 — immunology — Posted on 2023-09-15
2556 Sensory neuron population expansion enhances odour tracking through relaxed projection neuron adaptation
Takagi, S.; Abuin, L.; Stupski, S. D.; Arguello, J. R.; Prieto-Godino, L. L.; Stern, D. L.; Cruchet, S.; Alvarez-Ocana, R.; Wienecke, C. F. R.; van Breugel, F.; Auer, T. O.; Benton, R.
10.1101/2023.09.15.556782 — neuroscience — Posted on 2023-09-15
2559 Single-molecule FRET and tracking of transfected biomolecules: multi-dimensional protein dynamics in living cells
Anandamurugan, A.; Eidloth, A.; Wortmann, P.; Schrangl, L.; Aprile-Garcia, F.; Lan, C.; Sawarkar, R.; Schuetz, G.; Hugel, T.
10.1101/2023.09.15.557875 — biophysics — Posted on 2023-09-15
2560 MINSTED tracking of single biomolecules
Scheiderer, L.; von der Emde, H.; Hesselink, M.; Weber, M.; Hell, S. W.
10.1101/2023.09.15.557902 — biophysics — Posted on 2023-09-15
2562 Nature-Inspired Peptide of MtDef4 C-terminus Tail Enables Protein Delivery in Mammalian Cells
Adriana-Lifshits, L.; Breuer, Y.; Sova, M.; Gupta, S.; Kadosh, D.; Weinberg, E.; Hayouka, Z.; Bar, D. z.; Gal, M.
10.1101/2023.09.14.557695 — cell biology — Posted on 2023-09-15
2563 A novel approach to increase glial cell populations in brain microphysiological systems
Pantoja, I. E. M.; Ding, L.; Leite, P. E. C.; Marques, S. A.; Din, D. M. A.; Romero, J. C.; Zack, D. J.; Chamling, X.; Smirnova, L.
10.1101/2023.09.14.557775 — cell biology — Posted on 2023-09-15
2567 Naive primary neutrophils play a dual role in the tumor microenvironment
Babatunde, K. A.; Datta, R.; Ayuso, J. M.; Huttenlocher, A.; Skala, M. C.; Beebe, D. J.; Kerr, S. C.
10.1101/2023.09.15.557892 — cell biology — Posted on 2023-09-15
2568 c-Src induced vascular malformations require localised matrix degradation at focal adhesions
Essebier, P.; Schimmel, L.; Yordanov, T.; Keyser, M.; Yu, A.; Noordstra, I.; Hill, B.; Yap, A. S.; Stehbens, S. J.; Lagendijk, A.; Gordon, E.
10.1101/2023.09.15.557868 — cell biology — Posted on 2023-09-15
2569 A Novel Imaging Method (FIM-ID) Reveals that Myofibrillogenesis Plays a Major Role in the Mechanically Induced Growth of Skeletal Muscle
Jorgenson, K. W.; Hibbert, J. E.; Sayed, R. K.; Lange, A. N.; Godwin, J. S.; Mesquita, P. H.; Ruple, B. A.; McIntosh, M. C.; Kavazis, A. N.; Roberts, M. D.; Hornberger, T. A.
10.1101/2023.09.13.557204 — cell biology — Posted on 2023-09-15
2570 ARF6 as a novel activator of HIF-2alpha in pulmonary arterial hypertension
Fellows, A. L.; Chen, C.-N.; Xie, C.; Iyer, N.; Schmidt, L.; Yin, X.; Mayr, M.; Cowburn, A. S.; Zhao, L.; Wojciak-Stothard, B.
10.1101/2023.09.15.557917 — cell biology — Posted on 2023-09-15
2571 Optimising a self-assembling peptide hydrogel as a Matrigel alternative for 3-dimensional mammary epithelial cell culture
Lingard, E.; Dong, S.; Hoyle, A.; Appleton, E.; Hales, A.; Skaria, E.; Lawless, C.; Miller, A.; Domingos, M.; Saiani, A.; Swift, J.; Gilmore, A. P.
10.1101/2023.09.15.557894 — cell biology — Posted on 2023-09-15
2572 Skeletal Muscle Mitochondrial Morphology Negatively Affected by Loss of Xin
Martin, G.; Al-Sajee, D.; Gingrich, M.; Chattha, R.; Akcan, M.; Monaco, C. M.; Hughes, M. C.; Perry, C. G.; Rebalka, I. A.; Tarnopolsky, M. A.; Hawke, T. J.
10.1101/2023.09.14.557614 — cell biology — Posted on 2023-09-15
2575 Development and implementation of an integrated preclinical atherosclerosis database
Xiang, R. R.; Wang, Y.; Shuey, M. M.; Carvajal, B.; Wells, Q. S.; Beckman, J. A.; Jaffe, I. Z.
10.1101/2023.09.12.557423 — systems biology — Posted on 2023-09-15
2576 Human HYPOMAP: A comprehensive spatio-cellular map of the human hypothalamus
Tadross, J. A.; Steuernagal, L.; Dowsett, G.; Kentistou, K. A.; Lundh, S.; Porniece, M.; Klemm, P.; Rainbow, K.; Hvid, H.; Kania, K.; Polex-Wolf, J.; Knudsen, L. B.; Pyke, C.; Perry, J.; Lam, B. Y.; Bruening, J. C.; Yeo, G. S. H.
10.1101/2023.09.15.557967 — neuroscience — Posted on 2023-09-15
2577 Plant diversity darkspots for global collection priorities
Ondo, I.; Dhanjal-Adams, K.; Pironon, S.; Silvestro, D.; Deklerck, V.; Grace, O.; Monro, A. K.; Nicolson, N.; Walker, B.; Antonelli, A.
10.1101/2023.09.12.557387 — plant biology — Posted on 2023-09-15
2578 The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A
Olivieri, C.; Wang, Y.; Walker, C.; Subrahmanian, M. V.; Ha, K. N.; Bernlohr, D. A.; Gao, J.; Camilloni, C.; Vendruscolo, M.; Taylor, S. S.; Veglia, G.
10.1101/2023.09.12.557419 — biophysics — Posted on 2023-09-15
2581 Tuning gene expression to music: the compensatory effect of music on age-related cognitive disorders
Gomez-Carballa, A.; Navarro, L.; Pardo-Seco, J.; Bello, X.; Pischedda, S.; Viz-Lasheras, S.; Camino-Mera, A.; Curras, M. J.; Ferreiros, I.; Mallah, N.; Rey-Vazquez, S.; Redondo, L.; Dacosta-Urbieta, A.; Caamanho-Vinha, F.; Rivero-Calle, I.; Rodriguez-Tenrreiro, C.; Martinon-Torres, F.; Salas, A.
10.1101/2023.09.12.557408 — genomics — Posted on 2023-09-15
2583 Genomic analysis reveals limited hybridization among three giraffe species in Kenya
Coimbra, R. T. F.; Winter, S.; Muneza, A.; Fennessy, S.; Otiende, M.; Mijele, D.; Masiaine, S.; Stacy-Dawes, J.; Fennessy, J.; Janke, A.
10.1101/2023.09.12.557229 — evolutionary biology — Posted on 2023-09-15
2590 Amino acid auxotrophies in human gut bacteria are linked to higher microbiome diversity and long-term stability
Starke, S.; Harris, D. M.; Zimmermann, J.; Schuchardt, S.; Oumari, M.; Frank, D.; Bang, C.; Rosenstiel, P.; Schreiber, S.; Frey, N.; Franke, A.; Aden, K.; Waschina, S.
10.1101/2023.03.23.532984 — microbiology — Posted on 2023-09-15
2591 Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice
Aubert, N.; Purcarea, M.; Fornier, M.; Cagnet, L.; Naturel, M.; Casrouge, A.; Dietrich, G.; Dieu-Nosjean, M.-C.; Marodon, G.
10.1101/2023.09.12.557326 — immunology — Posted on 2023-09-15
2593 Non-preferential, but detrimental accumulation of macrophages with clonal hematopoiesis-driver mutations in cardiovascular tissues
Dederichs, T.-s.; Yerdenova, A.; Horstmann, H.; Vico, T.; Nuebling, S.; Peyronnet, R.; von zur Muehlen, C.; Heidt, T.; Wolf, D.; Westermann, D.; Hilgendorf, I.
10.1101/2023.09.11.557290 — immunology — Posted on 2023-09-15
2596 Soybean RIN4 represents a mechanistic link between plant immune and symbiotic signaling
Toth, K.; Kim, D.; Cho, S.-H.; Nguyen, C. T.; Hartanto, C.; Michno, J.-M.; Stec, A. O.; Stupar, R. M.; Stacey, G.
10.1101/2023.09.12.557450 — plant biology — Posted on 2023-09-15
2597 The HOMEODOMAIN-Like protein HDL mediates chromatin organization and rewires leaf epidermal patterning
Ali, A.; Kuan, C.; Hung, F.-Y.; Chen, T.-C.; Lee, H.-C.; Yang, S.-L.; Feng, Y.-R.; Wu, K.; Ho, C.-M. K.
10.1101/2023.09.13.557516 — plant biology — Posted on 2023-09-15
2598 ERF and WRKY transcription factors regulate IDA and abscission timing in Arabidopsis.
Galindo-Trigo, S.; Bagman, A.-M.; Ishida, T.; Sawa, S.; Brady, S. M.; Butenko, M. A.
10.1101/2023.09.12.557497 — plant biology — Posted on 2023-09-15
2600 ORM-mediated regulation of sphingolipid biosynthesis is essential for nodule formation in Aeschynomene evenia
Nouwen, N.; Pervent, M.; El M Chirgui, F.; Tellier, F.; Rios, M.; Horta-Araujo, N.; Klopp, C.; Gressent, F.; ARRIGHI, J.-F.
10.1101/2023.09.12.557380 — plant biology — Posted on 2023-09-15
2602 A bacterial effector directly targets Arabidopsis Argonaute 1 to suppress Pattern-triggered immunity and cause disease
Thiebeauld, O.; Charvin, M.; Singla Rastogi, M.; Perez-Quintero, A. L.; Yang, F.; Pontier, D.; Barraud, P.; Pouzet, C.; Bapaume, L.; Amsefe, D.; Li, G.; Deslandes, L.; Lagrange, T.; Alfano, J. R.; Navarro, L.
10.1101/215590 — plant biology — Posted on 2023-09-15
2603 GPR35 inhibits TRPA1-mediated colonic afferent hypersensitivity through suppression of Substance P release
Gupta, R. A.; Higham, J. P.; Urriola-Munoz, P.; Barker, K. H.; Paine, L. W.; Ghooraroo, J.; Hockley, J. R.; Rahman, T.; Smith, E. S. J.; Brown, A. J.; Suzuki, R.; Bulmer, D. C.
10.1101/2023.09.12.557415 — physiology — Posted on 2023-09-15
2604 Developing a safe 15-hour preservation protocol of donor kidneys using normothermic machine perfusion
Stone, J.; Cowey, W.; Bowers, C.; Stewart, A.; Armstrong, E.; Clancy, M.; Entwistle, T.; del Pozo, J.; Amin, K.; Fildes, J.
10.1101/2023.09.12.555854 — physiology — Posted on 2023-09-15
2605 Sclerotic prostate cancer bone metastasis: woven bone lesions with a twist.
Eltit, F. Y.; Wang, Q.; Jung, N.; Munshan, S.; Xie, D.; Xu, S.; Mojtahedzadeh, B.; Liu, D.; Corey, E.; True, L. E.; Morrissey, C.; Wang, R.; Cox, M. E.
10.1101/2023.09.11.557266 — cancer biology — Posted on 2023-09-15
2606 Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers
Centore, R. C.; Soares, L. M. M.; Topal, S.; Vaswani, R. G.; Ichikawa, K.; Li, Z.; Fan, H.; Setser, J. W.; Lahr, D. L.; Zawadzke, L. E.; Chen, X.; Barnash, K. D.; Muwanguzi, J.; Anthony, N.; Sandoval, G. J.; Feldman, K.; Elliott, G.; Adam, A.; Huang, D.; Davenport, Y.; Schiller, S.; Wilson, K. J.; Voigt, J.; Xu, L.; Hentemann, M.; Millan, D. S.; Chan, H. M.; Decicco, C. P.; Kruger, R. G.; Bellon, S. F.
10.1101/2023.09.11.557162 — cancer biology — Posted on 2023-09-15
2608 CAR T cells recognizing CD276 and Dual-CAR T cells against CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models
Timpanaro, A.; Piccand, C.; Dzhumashev, D.; Anton-Joseph, S.; Moser, J.; Robbi, A.; Roessler, J.; Bernasconi, M.
10.1101/2023.09.05.555125 — cancer biology — Posted on 2023-09-15
2609 A scaling law for epithelial tissue rheology
Cheikh, M. I.; Rondriguez, N.; Doubrovinski, K.
10.1101/2023.09.12.557407 — biophysics — Posted on 2023-09-15
2610 TGF-β3 increases the severity of radiation-induced oral mucositis and salivary gland fibrosis in a mouse model
Hanson, I.; Juvkam, I. S.; Zlygosteva, O.; Soland, T. M.; Galtung, H.; Malinen, E.; Edin, N. F. J.
10.1101/2023.09.12.557315 — biophysics — Posted on 2023-09-15
2611 Engineering an artificial catch bond using mechanical anisotropy
Liu, Z.; Liu, H.; Vera, A. M.; Yang, B.; Tinnefeld, P.; Nash, M.
10.1101/2023.09.12.557335 — biophysics — Posted on 2023-09-15
2615 Tissue-specific transfer-learning enables retasking of a general comprehensive model to a specific domain
Li, Q.; Perera, D.; Chen, Z.; Wen, W.; Wang, D.; Yan, J.; Shu, X.-o.; Zheng, W.; Guo, X.; Long, Q.
10.1101/2023.09.11.557208 — bioinformatics — Posted on 2023-09-15
2616 Bayesian Maximum Entropy Ensemble Refinement
Eltzner, B.; Hofstadler, J.; Rudolf, D.; Habeck, M.; de Groot, B.
10.1101/2023.09.12.557310 — bioinformatics — Posted on 2023-09-15
2618 Magnetically Powered Microwheel Thrombolysis of Occlusive Thrombi in Zebrafish
Pontius, M. H. H.; Ku, C.-J.; Osmond, M. J.; Disharoon, D.; Liu, Y.; Marr, D. W. M.; Neeves, K. B.; Shavit, J. A.
10.1101/2023.09.11.557256 — bioengineering — Posted on 2023-09-15
2619 Polyimide-Based Flexible Multi-Electrode Arrays: Synthesis, Microfabrication, and in-vivo Validation
Kumar, K.; Deshpande, K.; Kalur, N.; Chauhan, G.; Chugh, D.; Ganesh, S.; Ramakrishnan, A.
10.1101/2023.09.12.557325 — bioengineering — Posted on 2023-09-15
2621 Regulation of interferon signaling by transposon exonization
Pasquesi, G. I. M.; Allen, H.; Ivancevic, A.; Barbachano-Guerrero, A.; Joyner, O.; Guo, K.; Simpson, D. M.; Gapin, K.; Horton, I.; Nguyen, L.; Yang, Q.; Warren, C. J.; Florea, L. D.; Bitler, B. G.; Santiago, M. L.; Sawyer, S. L.; Chuong, E. B.
10.1101/2023.09.11.557241 — genomics — Posted on 2023-09-15
2622 Syntrichia ruralis: Emerging model moss genome reveals a conserved and previously unknown regulator of desiccation in flowering plants
Zhang, X.; Ekwealor, J. T. B.; Silva, A. T.; Yu, L.; Jones, A. K.; Mishle, B. D.; Nelson, A.; Oliver, M. J.
10.1101/2023.09.12.557352 — genomics — Posted on 2023-09-15
2625 Do Reticulate Relationships Between Tropical Trees Drive Diversification? Insights from Inga (Fabaceae)
Schley, R. J.; Pineiro, R.; Nicholls, J. A.; Pezzini, F. F.; Kidner, C.; Farbos, A.; Moore, K.; Ringelberg, J. J.; Twyford, A. D.; Dexter, K. G.; Pennington, T.
10.1101/2023.09.12.557345 — evolutionary biology — Posted on 2023-09-15
2626 Non fire-adapted dry forest of Northwestern Madagascar: escalating and devastating trends revealed by remote-sensing data
Percival, J. E. H.; Sato, H.; Razanaparany, T. P.; Harilalao, A. R.; Razafiarison, Z. L.; Kitajima, K.
10.1101/2023.09.12.557329 — ecology — Posted on 2023-09-15
2627 Snow Buntings, an arctic cold-specialist passerine, risk overheating under intense activity even at low air temperatures
O'Connor, R. S.; Love, O. P.; Regimbald, L.; Gerson, A. R.; Elliott, K. H.; Hargreaves, A. L.; Vezina, F.
10.1101/2023.09.11.557251 — ecology — Posted on 2023-09-15
2630 The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome.
Al-Aubodah, T.-A.; Aoudjit, L.; Pascale, G.; Perinpanayagam, M.; Langlais, D.; Bitzan, M.; Samuel, S. M.; Piccirillo, C. A.; Takano, T.
10.1101/2023.09.11.557079 — immunology — Posted on 2023-09-15
2631 Ligand requirements for immunoreceptor triggering
Barton, M. I.; Paterson, R. L.; Denham, E. M.; Goyette, J.; van der Merwe, P. A.
10.1101/2023.09.11.557203 — immunology — Posted on 2023-09-15
2632 PlexinD1 deficiency in CD11c+ dendritic cells exacerbates airway hyperresponsiveness and enhances IgE and mucus production in allergic asthma
shan, L.; Matloubi, M.; Okwor, I.; Kung, S.; Almiski, M. S.; Basu, S.; Halayko, A.; Koussih, L.; Soussi Gounni, A.
10.1101/2023.09.11.557276 — immunology — Posted on 2023-09-15
2634 Cancer-associated Fibroblast Spatial Heterogeneity and EMILIN1 Expression in Cancer Stroma Modulate TGF-beta Activity and CD8+ T-Cell Infiltration in Breast Cancer
Honda, C.; Kurozumi, S.; Fujii, T.; Pourquier, D.; Khellaf, L.; Boissiere, F.; Horiguchi, J.; Oyama, T.; Shirabe, K.; Colinge, J.; Yokobori, T.; Turtoi, A.
10.1101/2023.09.12.557312 — cancer biology — Posted on 2023-09-15
2635 Nanopore translocation reveals electrophoretic force on A- and B-form nucleic acids
Boskovic, F. N.; Maffeo, C.; Patino Guillen, G.; Tivony, R.; Aksimentiev, A.; Keyser, U. F.
10.1101/2023.09.12.557357 — biophysics — Posted on 2023-09-15
2640 Enabling Model-based Design for closed-loop applications in neuroengineering
Di Florio, M.; Bornat, Y.; Care, M.; Rosa Cota, V.; Buccelli, S.; Chiappalone, M.
10.1101/2023.09.11.557151 — bioengineering — Posted on 2023-09-15
2641 Identification of inflammatory biomarkers in IgA nephropathy using the NanoString technology: a validation study
Gaumond, L.; Lamarche, C.; Beauchemin, S.; Henley, N.; Elftouh, N.; Gerarduzzi, C.; Laurin, L.-P.
10.1101/2023.09.11.556864 — genomics — Posted on 2023-09-15
2642 Predicting photosynthetic pathway from anatomy using machine learning
Gilman, I. S.; Heyduk, K.; Maya-Lastra, C. A.; Hancock, L. P.; Edwards, E. J.
10.1101/2023.09.11.557216 — evolutionary biology — Posted on 2023-09-15
2643 Olfactory learning in Drosophila requires O-GlcNAcylation of mushroom body ribosomal subunits
Yu, H.; Liu, D.; Zhang, Y.; Tang, R.; Fan, X.; Mao, S.; Lv, L.; Chen, F.; Qin, H.; Zhang, Z.; van Alten, D. M.; Yang, B.; Yuan, K.
10.1101/2023.09.14.557796 — cell biology — Posted on 2023-09-15
2648 OneFlowTraX: A User-Friendly Software for Super-Resolution Analysis of Single-Molecule Dynamics and Nanoscale Organization
Rohr, L.; Ehinger, A.; Rausch, L.; Burmeister, N. G.; Meixner, A. J.; Gronnier, J.; Harter, K.; Kemmerling, B.; zur Oven-Krockhaus, S.
10.1101/2023.08.10.552827 — plant biology — Posted on 2023-09-15
2649 Monkeybread: A Python toolkit for the analysis of cellular niches in single-cell resolution spatial transcriptomics data
Bernstein, M. N.; Scott, D.; Hession, C. C.; Nieuwenhuis, T.; Gerritsen, J.; Tabrizi, S.; Nandivada, V.; Huggins, M. A.; Duan, M.; Malu, S.; Tang, M.
10.1101/2023.09.14.557736 — bioinformatics — Posted on 2023-09-15
2657 Improving the discovery of rare variants associated with alcohol problems by leveraging machine learning phenotype prediction and functional information.
Ahangari, M.; Gentry, A. E.; Hassan, M.; Nguyen, T. H.; Kendler, K. S.; Bacanu, S.-A.; Peterson, R. E.; Riley, B. P.; Webb, B. T.
10.1101/2023.09.11.557163 — genetics — Posted on 2023-09-15
2659 Ether phospholipids modulate somatosensory responses by tuning multiple receptor functions in Drosophila
Suito, T.; Nagao, K.; Deng, X.; Ganser, C.; Uchihashi, T.; Tsutsumi, M.; Nemoto, T.; Hara, Y.; Tominaga, M.; Sokabe, T.
10.1101/2023.09.12.556286 — molecular biology — Posted on 2023-09-15
2660 Distinct sources and behavioral correlates of macaque motor cortical low and high beta
Nougaret, S.; Lopez-Galdo, L.; Caytan, E.; Poitreau, J.; Barthelemy, F. V.; Kilavik, B. E.
10.1101/2023.03.28.534535 — neuroscience — Posted on 2023-09-15
2662 Engineering a plant polyketide synthase for the biosynthesis of methylated flavonoids
Peng, B.; Zhang, L.; He, S.; Oerlemans, R.; Quax, W. J.; Groves, M. R.; Haslinger, K.
10.1101/2022.10.02.510496 — biochemistry — Posted on 2023-09-15
2666 Decomposing drivers in avian insectivory: large-scale effects of climate, habitat and bird diversity
SCHILLE, L.; VALDES-CORRECHER, E.; ARCHAUX, F.; BALACENOIU, F.; BJOERN, M. C.; BOGDZIEWICZ, M.; BOIVIN, T.; BRANCO, M.; DAMESTOY, T.; DE GROOT, M.; DOBROSAVLJEVIC, J.; DUDUMAN, M.-L.; DULAURENT, A.-M.; GREEN, S.; GRUNWALD, J.; EOTVOS, C. B.; FATICOV, M.; FERNANDEZ-CONRADI, P.; FLURY, E.; FUNOSAS, D.; GALMAN, A.; GOSSNER, M. M.; GRIPENBERG, S.; GROSU, L.; Hagge, J.; HAMPE, A.; HARVEY, D.; HOUSTON, R.; ISENMANN, R.; KAVCIC, A.; KOZLOV, M. V.; LANTA, V.; LE TILLY, B.; LOPEZ VAAMONDE, C.; MALLICK, S.; MANTYLA, E.; MARELL, A.; MILANOVIC, S.; MOLNAR, M.; MOREIRA, X.; MOSER, V.; MRAZOVA, A.; MUSOLIN,
10.1101/2023.01.19.524212 — ecology — Posted on 2023-09-15
2667 Permanent Neonatal diabetes-causing Insulin mutations have dominant negative effects on beta cell identity
Zhang, Y.; Sui, L.; Du, Q.; Haataja, L.; Yin, Y.; Viola, R.; Xu, S.; Nielsson, C. U.; Leibel, R. L.; Barbetti, F.; Arvan, P.; Egli, D.
10.1101/2023.09.01.555839 — cell biology — Posted on 2023-09-15
2668 Characterization of sinking and suspended microeukaryotic communities in spring Oyashio waters
Yang, Q.; Yang, Y.; Xia, J.; Fukuda, H.; Okazaki, Y.; Nagata, T.; Ogata, H.; Endo, H.
10.1101/2023.09.13.557659 — microbiology — Posted on 2023-09-15
2670 Beta bursts question the ruling power for brain-computer interfaces
Papadopoulos, S.; Szul, M. J.; Congedo, M.; Bonaiuto, J. J.; Mattout, J.
10.1101/2023.09.11.557139 — neuroscience — Posted on 2023-09-15
2672 Reconfigurations of cortical manifold structure during reward-based motor learning
Nick, Q.; Gale, D. J.; Areshenkoff, C.; De Brouwer, A. J.; Nashed, J. Y.; Wammes, J.; Flanagan, J. R.; Smallwood, J.; Gallivan, J.
10.1101/2023.07.05.547880 — neuroscience — Posted on 2023-09-15
2677 Expression of cell-wall related genes is highly variable and correlates with sepal morphology
Hartasanchez, D. A.; Kiss, A. K.; Battu, V.; Soraru, C.; Delgado Vaquera, A.; Massinon, F.; Braso-Vives, M.; Mollier, C.; Martin-Magnette, M.-L.; Boudaoud, A.; Moneger, F.
10.1101/2022.04.26.489498 — plant biology — Posted on 2023-09-15
2679 BeeBDC: An R package and globally synthesised and flagged bee occurrence dataset
Dorey, J. B.; Fischer, E. E.; Chesshire, P. R.; Nava-Bolanos, A.; OReilly, R. L.; Bossert, S.; Collins, S. M.; Lichtenberg, E. M.; Tucker, E. M.; Smith-Pardo, A.; Falcon-Brindis, A.; Guevara, D. A.; Ribeiro, B.; de Pedro, D.; Pickering, J.; James, K.-L.; Parys, K. A.; McCabe, L. M.; Rogan, M. S.; Minckley, R. L.; Velazco, S. J. E.; Griswold, T.; Zarrillo, T. A.; Jetz, W.; Sica, Y. V.; Orr, M. C.; Guzman, L. M.; Ascher, J. A.; Hughes, A. C.; Cobb, N. S.
10.1101/2023.06.30.547152 — ecology — Posted on 2023-09-15
2681 SanPy: A whole-cell electrophysiology analysis pipeline.
Guarina, L.; Le, J. T.; Griffith, T.; Santana, L. F.; Cudmore, R. H.
10.1101/2023.05.06.539660 — physiology — Posted on 2023-09-15
2682 StereoSiTE: A framework to spatially and quantitatively profile the cellular neighborhood organized iTME
Liu, X.; Qu, C.; Liu, C.; Zhu, N.; Huang, H.; Teng, F.; Huang, C.; Luo, B.; Liu, X.; Xu, Y.; Xie, M.; Xi, F.; Li, M.; Wu, L.; Li, Y.; Chen, A.; Xu, X.; Liao, S.; Zhang, J.
10.1101/2022.12.31.522366 — cancer biology — Posted on 2023-09-15
2683 A transcriptome-wide meta-analysis reveals lack of cancer-cell intrinsic determinants of response to immune checkpoint blockade
Guo, Y. A.; Kulshrestha, T.; Chang, M. M.; Kassam, I.; Revkov, E.; Rizzetto, S.; Tan, A.; Tan, D.; Tan, I. B.; Jacobsen Skanderup, A.
10.1101/2023.07.30.551135 — cancer biology — Posted on 2023-09-15
2684 MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites
Wang, C.; Dong, Y.; Li, C.; Oberstaller, J.; Zhang, M.; Gibbons, J.; Pires, C. V.; Xiao, M.; Zhu, L.; Jiang, R.; Kim, K.; Miao, J.; Otto, T. D.; Cui, L.; Adams, J. H.; Liu, X.
10.1101/2022.09.21.508539 — bioinformatics — Posted on 2023-09-15
2687 Single-Cell Imaging Maps Inflammatory Cell Subsets to Pulmonary Arterial Hypertension Vasculopathy
Ferrian, S.; Cao, A.; McCaffrey, E. F.; Saito, T.; Greenwald, N. F.; Nicolls, M. R.; Bruce, T.; Zamanian, R. T.; Del Rosario, P. A.; Rabinovitch, M.; Angelo, M.
10.1101/2022.12.03.518033 — immunology — Posted on 2023-09-15
2688 Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11.2 Deletion Syndrome
Gundersen, B. B.; O'Brien, W. T.; Schaffler, M. D.; Schultz, M. N.; Tsukahara, T.; Lorenzo, S. M.; Nalesso, V.; Clayton, A. H. L.; Abel, T.; Crawley, J. N.; Datta, S. R.; Herault, Y.
10.1101/2023.05.01.538987 — neuroscience — Posted on 2023-09-15
2689 Timing and location of speech errors induced by direct cortical stimulation
Kabakoff, H.; Yu, L.; Friedman, D.; Dugan, P.; Doyle, W.; Devinsky, O.; Flinker, A.
10.1101/2023.09.14.557732 — neuroscience — Posted on 2023-09-15
2690 Skeletal Muscle TFEB Signaling Promotes Central Nervous System Function and Reduces Neuroinflammation during Aging and Neurodegenerative Disease
Matthews, I.; Birnbaum, A.; Gromova, A.; Huang, A. W.; Liu, K.; Liu, E. A.; Coutinho, K.; McGraw, M.; Patterson, D. C.; Banks, M. T.; Nobles, A. C.; Nguyen, N.; Merrihew, G. E.; Wang, L.; Baeuerle, E.; Fernandez, E.; Musi, N.; MacCoss, M. J.; Miranda, H. C.; La Spada, A. R.; Cortes, C. J.
10.1101/2022.03.07.482891 — neuroscience — Posted on 2023-09-15
2694 A robust measure of metacognitive sensitivity and confidence criteria
Arnold, D. H.; Clendinen, M.; Johnston, A.; Lee, A. L. F.; Yarrow, K.
10.1101/2023.09.12.557480 — neuroscience — Posted on 2023-09-14
2697 Multi-areal neural dynamics encode human decision making
Overton, J. A.; Moxon, K. A.; Stickle, M. P.; Peters, L. M.; Lin, J. J.; Chang, E. F.; Knight, R. T.; Hsu, M.; Saez, I.
10.1101/2022.08.05.502992 — neuroscience — Posted on 2023-09-14
2700 Physical mechanisms of red blood cell splenic filtration
Moreau, A.; Yaya, F.; Lu, H.; Surendranath, A.; Charrier, A.; Dehapiot, B.; Helfer, E.; Viallat, A.; Peng, Z.
10.1101/2023.01.10.523245 — biophysics — Posted on 2023-09-14
2706 Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study
Georgiadis, F.; Lariviere, S.; Glahn, D.; Hong, E.; Kochunov, P.; Mowry, B.; Loughland, C.; Pantelis, C.; Henskens, F.; Green, M.; Cairns, M.; Michie, P.; Rasser, P.; Tooney, P.; Scott, R.; Catts, S.; Schall, U.; Carr, V.; Quide, Y.; Krug, A.; Stein, F.; Nenadic, I.; Brosch, K.; Kircher, T.; Gur, R.; Gur, R.; Satterthwaite, T.; Karuk, A.; Clotet, E.; Radua, J.; Claramonte, P.; Salvador, R.; Spalletta, G.; Voineskos, A.; Sim, K.; Facorro, B.; Gutierrez, D.; Ehrlich, S.; Crossley, N.; Grotegerd, D.; Repple, J.; Lencer, R.; Dannlowski, U.; Calhoun, V.; Demro, C.; Ramsay, I.; Sponheim, S.; Schmidt
10.1101/2023.02.12.527904 — neuroscience — Posted on 2023-09-14
2710 Zinc is Essential for the Copper Reductase Activity of Yeast Nucleosomes
Vogelauer, M.; Cheng, C.; Karimian, A.; Golshan Iranpour, H.; Kurdistani, S. K.
10.1101/2023.09.14.557765 — biochemistry — Posted on 2023-09-14
2717 Characterization of sinking and suspended microeukaryotic communities in spring Oyashio waters
Qingwei, Y.; Yanhui, Y.; Jun, X.; Hideki, F.; Yusuke, O.; Toshi, N.; Ogata, H.; Endo, H.
10.1101/2023.09.13.557659 — microbiology — Posted on 2023-09-14
2718 The multiplicity of Thioredoxin systems meets the specific needs of Clostridia
Anjou, C.; Lotoux, A.; Zhukova, A.; Royer, M.; Caulat, L. C.; Capuzzo, E.; Morvan, C.; Martin-Verstraete, I.
10.1101/2023.09.14.557728 — microbiology — Posted on 2023-09-14
2720 Antiviral Wolbachia strains associate with Aedes aegypti endoplasmic reticulum membranes and disturb host cell lipid distribution to restrict dengue virus replication.
Kriiger-Loterio, R.; Monson, E.; Templin, R.; Bruyne, J. T.; Flores, H. A.; Mackenzie, J.; Ramm, G.; Helbig, K.; Simmons, C. P.; Fraser, J. E.
10.1101/2023.09.14.557745 — microbiology — Posted on 2023-09-14
2722 Cell2Sentence: Teaching Large Language Models the Language of Biology
Levine, D.; Rizvi, S. A.; Levy, S.; Pallikkavaliyaveetil MohammedSheriff, N.; Wu, R.; Zhang, Z.; Fonseca, A.; Chen, X.; Ghadermarzi, S.; Dhodapkar, R. M.; van Dijk, D.
10.1101/2023.09.11.557287 — bioinformatics — Posted on 2023-09-14
2724 Ensembling Unets, sparse representation and low dimensional visualization for rare chromosomal aberration detection in light microscopy images
Deschemps, A.; Gregoire, E.; Martinez, J. S.; Vaurijoux, A.; Fernandez, P.; Dugue, D.; Bobyk, L.; Valente, M.; Gruel, G.; Moebel, E.; Benajdaoud, M. A.; Kervrann, C.
10.1101/2023.09.11.557124 — bioinformatics — Posted on 2023-09-14
2725 Photoswitchable binders enable temporal dissection of endogenous protein function
Westberg, M.; Song, D.; Duong, V.; Fernandez, D.; Huang, P.-S.; Lin, M. Z.
10.1101/2023.09.14.557687 — biochemistry — Posted on 2023-09-14
2728 Genetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic
Crits-Christoph, A.; Levy, J. I.; Pekar, J.; Goldstein, S. A.; Singh, R.; Hensel, Z.; Gangavarapu, K.; Rogers, M. B.; Moshiri, N.; Garry, R. f.; Holmes, E. C.; Koopmans, M. P. G.; Lemey, P.; Popescu, S.; Rambaut, A.; Robertson, D. L.; Suchard, M. A.; Wertheim, J.; Rasmussen, A. L.; Andersen, K. G.; Worobey, M.; Debarre, F.
10.1101/2023.09.13.557637 — genomics — Posted on 2023-09-14
2731 The Dynamics of Synthesis and Localization of Jumbo Phage RNA Polymerases inside Infected Cells
Antonova, D.; Belousova, V. V.; Zhivkoplias, E.; Sobinina, M.; Artamonova, T.; Vishnyakov, I. E.; Kurdyumova, I.; Arseniev, A.; Morozova, N.; Severinov, K.; Khodorkovskii, M.; Yakunina, M.
10.1101/2023.09.14.557509 — molecular biology — Posted on 2023-09-14
2732 circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
Okholm, T. L. H.; Kamstrup, A. B.; Nielsen, M. M.; Hollensen, A. K.; Graversgaard, M. L.; Kristensen, L. S.; Vang, S.; Park, S. S.; Yeo, G. W.; Dyrskjot, L.; Kjems, J.; Pedersen, J. S.; Damgaard, C. K.
10.1101/2023.09.14.557527 — molecular biology — Posted on 2023-09-14
2733 DNA methylation shapes the Polycomb landscape during the exit from naïve pluripotency
Albert, J. R.; Urli, T.; Monteagudo-Sanchez, A.; Le Breton, A.; Sultanova, A.; David, A.; Schulz, M.; Greenberg, M. V. C.
10.1101/2023.09.14.557729 — molecular biology — Posted on 2023-09-14
2737 A collection of diverse bacteriophages for biocontrol of ESBL- and AmpC-β-lactamase-producing E. coli
Vitt, A. R.; Sorensen, A. N.; Bojer, M. S.; Bortolaia, V.; Sorensen, M. C. H.; Brondsted, L.
10.1101/2023.09.14.557699 — microbiology — Posted on 2023-09-14
2739 Choice of Ultrafilter affects Recovery Rate of Bacteriophages
Larsen, F.; Offersen, S. M.; Li, V. R.; Deng, L.; Nielsen, D. S.; Rasmussen, T. S.
10.1101/2023.09.14.557126 — microbiology — Posted on 2023-09-14
2740 Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water
Zizelski Valenci, G.; Ohad, S.; Robinstein, M.; Assaly, S.; Kutikov, I.; Groisman, L.; Murik, O.; Zeevi, D. A.; Ben David, R.; Farber, A.; Dveyrin, Z.; Rorman, E.; Nissan, I.
10.1101/2023.09.14.557692 — microbiology — Posted on 2023-09-14
2741 A novel, tissue-associated and vertically transmitted bacterial symbiont in the coral Pocillopora acuta
Maire, J.; Ching, S. J. T. M.; Damjanovic, K.; Epstein, H. E.; Judd, L. M.; Blackall, L. L.; van Oppen, M. J. H.
10.1101/2023.09.14.557667 — microbiology — Posted on 2023-09-14
2742 Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19
Narasimhan, H.; Cheon, I. S.; Qian, W.; Hu, S.; Parimon, T.; Zang, C.; Chen, P.; Sun, J.
10.1101/2023.09.13.557622 — immunology — Posted on 2023-09-14
2744 Linking Gba1 E326K mutation to microglia activation and mild age-dependent dopaminergic Neurodegeneration
Kweon, S. H.; Ryu, H. G.; Park, H.; Lee, S.; Kim, N.; Kwon, S.-H.; Ma, S.; Kim, S.; Ko, H. S.
10.1101/2023.09.14.557673 — neuroscience — Posted on 2023-09-14
2745 Discovery of a functionally selective serotonin 5-HT1A receptor agonist for the treatment of pain
Ullrich, A.; Schneider, J.; Braz, J. M.; Neu, E.; Staffen, N.; Stanek, M.; Blahova, J.; Hove, T.; Albert, T.; Allikalt, A.; Lober, S.; Bhardwaj, K.; Rodriguez-Rosado, S.; Fink, E. A.; Rasmussen, T.; Hubner, H.; Inoue, A. A.; Shoichet, B. K.; Basbaum, A.; Bottcher, B.; Weikert, D.; Gmeiner, P.
10.1101/2023.09.11.557127 — pharmacology and toxicology — Posted on 2023-09-14
2748 Sodium chloride in the tumor microenvironment enhances T-cell metabolic fitness and cytotoxicity
Soll, D.; Arunkumar, M.; Alissa-Alkhalaf, M.; Sun, S.; Nguyen, T.; Chu, C.-F.; Lutz, V.; Schauble, S.; Garcia-Ribelles, I.; Mueller, M.; Michalke, B.; Panagiotou, G.; Schatzlmaier, P.; Stockinger, H.; Schamel, W.; Huber, M.; Zielinski, C. E.
10.1101/2023.09.14.557686 — immunology — Posted on 2023-09-14
2749 Anti-inflammatory role of APRIL by modulating regulatory B cells in antigen-induced arthritis
Carvalho-Santos, A.; Kuhnert, L. R. B.; Hahne, M.; Vasconcellos, R.; Carvalho-Pinto, C. E.; Villa-Verde, D. M. S.
10.1101/2023.09.12.557472 — immunology — Posted on 2023-09-14
2753 Lipid network of plasma extracellular vesicles reveals sex-based differences in the lipidomic profile from patients with alcohol use disorder
Perpina-Clerigues, C.; Mellado, S.; Galiana-Rosello, C.; Fernandez-Regueras, M.; Marcos, M.; Garcia-Garcia, F.; Pascual, M.
10.1101/2023.09.12.557479 — pathology — Posted on 2023-09-14
2754 scEGOT: Single-cell trajectory inference framework based on entropic Gaussian mixture optimal transport
Yachimura, T.; Wang, H.; Imoto, Y.; Yoshida, M.; Tasaki, S.; Kojima, Y.; Yabuta, Y.; Saitou, M.; Hiraoka, Y.
10.1101/2023.09.11.557102 — bioinformatics — Posted on 2023-09-14
2756 Shrinking in the dark: Parallel endosymbiont genome erosions are associated with repeated host transitions to an underground life
Beasley-Hall, P. G.; Kinjo, Y.; Rose, H. A.; Walker, J.; Foster, C. S. P.; Kovacs, T. G. L.; Bourguignon, T.; Ho, S. Y. W.; Lo, N.
10.1101/2023.09.11.557272 — genomics — Posted on 2023-09-14
2757 Evolutionary origin of morphologically cryptic species imprints co-occurrence and sympatry patterns
Delic, T.; Borko, S.; Premate, E.; Rexhepi, B.; Alther, R.; Knuesel, M.; Malard, F.; Weber, D.; Stoch, F.; Flot, J.-F.; Fiser, C.; Altermatt, F.
10.1101/2023.09.13.557531 — ecology — Posted on 2023-09-14
2758 Resilience assessment in complex natural systems.
Sguotti, C.; Vasilakopoulos, P.; Tzanatos, E.; Frelat, R.
10.1101/2023.09.12.557305 — ecology — Posted on 2023-09-14
2759 A fourth locus in the Plasmodium falciparum genome associated with sickle haemoglobin
Hamilton, W. L.; Band, G.; Aniweh, Y.; Asoala, V.; Drury, E.; Rockett, K. A.; Awandare, G. A.; Kwiatkowski, D. P.; Amenga-Etego, L. N.
10.1101/2023.09.14.557461 — microbiology — Posted on 2023-09-14
2760 An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies
Wang, Y.; Lv, H.; Lei, R.; Yeung, Y.-H.; Shen, I. R.; Choi, D.; Teo, Q. W.; Tan, T. J. C.; Gopal, A. B.; Chen, X.; Graham, C. S.; Wu, N. C.
10.1101/2023.09.11.557288 — immunology — Posted on 2023-09-14
2762 Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2.
Nazish, I.; Mamais, A.; Mallach, A.; Bettencourt, C.; Kaganovich, A.; Warner, T. T.; Hardy, J.; Lewis, P. A.; Pocock, J. M.; Cookson, M. R.; Bandopadhyay, R.
10.1101/2023.09.14.557532 — neuroscience — Posted on 2023-09-14
2765 Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila
Held, M.; Bisen, R. S.; Zandawala, M. M.; Chockley, A. S.; Balles, I. S.; Hilpert, S.; Liessem, S.; Cascino-Milani, F.; Ache, J. M.
10.1101/2023.09.14.557555 — neuroscience — Posted on 2023-09-14
2766 Attenuated incubation of ethanol-induced conditioned taste aversion in a model of dependence
Ramirez, L. A.; Przybysz, K. R.; Pitock, J. R.; Starr, E. M.; Yang, H.; Glover, E. J.
10.1101/2023.09.13.557582 — neuroscience — Posted on 2023-09-14
2768 Machine assisted annotation in neuroanatomy
Qian, K.; Kleinfeld, D.; Friedman, B.; Freund, Y.
10.1101/2023.09.13.557658 — neuroscience — Posted on 2023-09-14
2770 Inflammation and autophagy dysfunction in metachromatic leukodystrophy: a central role for mTOR?
Catchpole, Z.; Hartanto, A. E.; Kataura, T.; Palmowski, P.; Porter, A.; Ulicna, K.; Harris, K. S.; Korolchuk, V. I.; Erskine, D.
10.1101/2023.09.14.557720 — neuroscience — Posted on 2023-09-14
2772 Mapping glymphatic solute transportation through the perivascular space of hippocampal arterioles with 14 Tesla MRI
Zhou, X. A.; Man, W.; Liu, X.; Jiang, Y.; Hike, D. C.; Cid, L. G.; Choi, S. C.; Lin, C.; Mohammed, S.; Yu, X.
10.1101/2023.09.14.557634 — neuroscience — Posted on 2023-09-14
2773 A role for LGI1 in regulating pain sensitivity.
Farah, A.; Paul, I.; Cheng, H.; Su, Y.; Poplawski, P.; Tseng, M.; Dawes, J. M.
10.1101/2023.09.13.557645 — neuroscience — Posted on 2023-09-14
2774 A hierarchical atlas of the human cerebellum for functional precision mapping
Nettekoven, C. R.; Zhi, D.; Shahshahani, L.; Luisa Pinho, A.; Saadon-Grosmann, N.; Diedrichsen, J.
10.1101/2023.09.14.557689 — neuroscience — Posted on 2023-09-14
2775 GABA Release From Central Amygdala Neurotensin Neurons Differentially Modulates Reward and Consummatory Behavior in Male and Female Mice
Gereau, G. B.; Torruella-Suarez, M. L.; Sizer, S. E.; Zhou, D.; Wykoff, L. A.; Boyt, K. M.; Alvarez-Pamir, A.; McElligott, Z. A.
10.1101/2023.09.14.557768 — neuroscience — Posted on 2023-09-14
2777 Mapping the Single-cell Differentiation Landscape of Osteosarcoma
Truong, D. D.; Weistuch, C.; Murgas, K. A.; Deasy, J. O.; Mikos, A. G.; Tannenbaum, A.; Ludwig, J.
10.1101/2023.09.13.555156 — cancer biology — Posted on 2023-09-14
2780 UNNT: A novel Utility for comparing Neural Net and Tree-based models
Gutta, V. V.; Ganakammal, S. R.; Jones, S.; Beyers, M.; Chandrasekaran, S.
10.1101/2023.09.12.557300 — bioinformatics — Posted on 2023-09-14
2782 OBIA: An Open Biomedical Imaging Archive
Jin, E.; Zhao, D.; Wu, G.; Zhu, J.; Wang, Z.; Wei, Z.; Zhang, S.; Wang, A.; Tang, B.; Chen, X.; Sun, Y.; Zhang, Z.; Zhao, W.; Meng, Y.
10.1101/2023.09.12.557281 — bioinformatics — Posted on 2023-09-14
2783 Engineering heterothallic strains in fission yeast
Garcia-Ruano, D.; Hsu, I.; Leray, B.; Billard, B.; Liti, G.; Coudreuse, D.
10.1101/2023.09.13.557521 — genetics — Posted on 2023-09-14
2784 Evolutionary prediction for new echolocators
Liu, Q.; Hua, Q.-Y.; Sun, S.; He, S.-W.; Li, M.-C.; Shi, L.-Y.; Chen, P.; Ma, Y.-S.; Zhang, Q.; Jiang, X.-L.; Wang, Y.; Shi, P.
10.1101/2023.09.13.556757 — evolutionary biology — Posted on 2023-09-14
2786 Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology
Philip, D. T.; Goins, N. M.; Catanzaro, N. J.; Misumi, I.; Whitmire, J. K.; Atkins, H. M.; Lazear, H. M.
10.1101/2023.09.11.557277 — immunology — Posted on 2023-09-14
2787 Virtual biomarkers: predicting immune status using label-free holotomography of individual human monocytes and machine learning analysis
Lee, M.; Kim, G.; Lee, M. S.; Shin, J. W.; Lee, J. H.; Ryu, D. H.; Kim, Y. S.; Chung, Y.; Kim, K. S.; Park, Y.
10.1101/2023.09.12.557503 — immunology — Posted on 2023-09-14
2789 Dynamics of motor direction representation in the primate premotor and primary motor cortices during sensorimotor learning
Ebina, T.; Sasagawa, A.; Hong, D.; Setsuie, R.; Obara, K.; Masamizu, Y.; Kondo, M.; Terada, S.-I.; Ozawa, K.; Uemura, M.; Takaji, M.; Watakabe, A.; Kobayashi, K.; Ohki, K.; Yamamori, T.; Murayama, M.; Matsuzaki, M.
10.1101/2023.09.13.556461 — neuroscience — Posted on 2023-09-14
2793 The contribution of early language exposure to the cortical tracking of speech
Perez-Navarro, J.; Klimovich-Gray, A.; Lizarazu, M.; Piazza, G.; Molinaro, N.; Lallier, M.
10.1101/2023.09.14.557701 — neuroscience — Posted on 2023-09-14
2794 Replay-triggered Brain-wide Activation in Humans
Huang, Q.; Xiao, Z.; Yu, Q.; Luo, Y.; Xu, J.; Dolan, R.; Behrens, T.; Liu, Y.
10.1101/2023.09.14.557724 — neuroscience — Posted on 2023-09-14
2795 Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation
Ridwan, S. M.; Poursaeid, S.; Beard, E. K.; Twillie, A.; Bener, M. B.; Antel, M.; Cowan, A. E.; Matsuda, S.; Inaba, M.
10.1101/2022.09.13.507868 — developmental biology — Posted on 2023-09-14
2796 Heterogeneous complement and microglia activation mediates stress-induced synapse loss
Soteros, B. M.; Tillmon, H.; Wollet, M.; General, J.; Chin, H.; Lee, J. B.; Carreno, F. R.; Morilak, D. A.; Kim, J. H.; Sia, G. M.
10.1101/2023.06.28.546889 — neuroscience — Posted on 2023-09-14
2798 A system of feed-forward cerebellar circuits that extend and diversify sensory signaling
Hariani, H. N.; Algstam, A. B.; Candler, C. T.; Witteveen, I. F.; Sidhu, J. K.; Balmer, T. S.
10.1101/2023.04.11.536335 — neuroscience — Posted on 2023-09-14
2799 Single-cell analysis of prenatal and postnatal human cortical development
Velmeshev, D.; Perez, Y.; Yan, Z.; Valencia, J. E.; Castaneda-Castellanos, D. R.; Wang, L.; Schirmer, L.; Mayer, S.; Wick, B.; Wang, S.; Nowakowski, T. J.; Paredes, M.; Huang, E. J. J.; Kriegstein, A.
10.1101/2022.10.24.513555 — neuroscience — Posted on 2023-09-14
2801 Synergistic induction of blood-brain barrier properties
Porkolab, G.; Meszaros, M.; Szecsko, A.; Vigh, J. P.; Walter, F. R.; Figueiredo, R.; Kalomista, I.; Vizsnyiczai, G.; Jan, J.-S.; Gosselet, F.; Vastag, M.; Hudson, N.; Campbell, M.; Veszelka, S.; Deli, M. A.
10.1101/2023.02.09.527899 — bioengineering — Posted on 2023-09-14
2802 Acetylation-dependent coupling between G6PD activity and apoptotic signaling
Wu, F.; Muskat, N. H.; Dvilansky, I.; Koren, O.; Shahar, A.; Gazit, R.; Elia, N.; Arbely, E.
10.1101/2023.02.19.529048 — biochemistry — Posted on 2023-09-14
2805 The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs
Murray, G. G. R.; Hossain, A. S. M. M.; Miller, E. L.; Bruchmann, S.; Balmer, A. J.; Matuszewska, M.; Herbert, J.; Hadjirin, N. F.; Mugabi, R.; Li, G.; Ferrando, M. L.; Fernades de Oliveira, I. M.; Nguyen, T.; Yen, P. L. K.; Phuc, H. D.; Moe, A. Z.; Wai, T. S.; Gottschalk, M.; Aragon, V.; Valentin-Weigand, P.; Heegaard, P. M. H.; Vrieling, M.; Maw, M. T.; Myint, H. T.; Win, Y. T.; Hoa, N. T.; Bentley, S. D.; Clavijo, M. J.; Wells, J. M.; Tucker, A. W.; Weinert, L. A.
10.1101/2023.05.17.540811 — evolutionary biology — Posted on 2023-09-14
2808 Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi
Stuchly, J.; Novak, D.; Brdickova, N.; Hadlova, P.; Iksi, A.; Kuzilkova, D.; Svaton, M.; Saad, G. A.; Engel, P.; Luche, H.; Sousa, A. E.; Almeida, A. R. M.; Kalina, T.
10.1101/2023.07.13.547329 — immunology — Posted on 2023-09-14
2809 Bayesian modeling disentangles language versus executive control disruption in stroke
Hartwigsen, G.; Lim, J.-S.; Bae, H.-J.; Yu, K.-H.; Kuijf, H. J.; Weaver, N. A.; Biesbroek, J. M.; Kopal, J.; Bzdok, D.
10.1101/2023.08.06.552147 — neuroscience — Posted on 2023-09-14
2810 WITHDRAWN: Identification and functional analysis of extrachromosomal circular DNA in plasma extracellular vesicles of liver failure patients
Xiang, X.; Hong, X.; Yu, Y.; Li, J.; Yu, J.; Xiao, W.; Chen, C.; Huang, D.; Zhong, T.; Li, J.; Qian, Y.; Li, Z.
10.1101/2023.08.16.553522 — genomics — Posted on 2023-09-14
2813 Seasonality of host-seeking Ixodes ricinus nymph abundance in relation to climate
Hoch, T.; Madouasse, A.; Jacquot, M.; Wongnak, P.; Beugnet, F.; Bournez, L.; Huard, F.; Moutailler, S.; Plantard, O.; Poux, V.; Rene-Martellet, M.; Vayssier-Taussat, M.; Verheyden, H.; Vourc'h, G.; Chalvet-Monfray, K.; Agoulon, A.
10.1101/2022.07.25.501416 — ecology — Posted on 2023-09-14
2816 A Benchmark Dataset for Machine Learning in Ecotoxicology
Schuer, C.; Gasser, L.; Perez-Cruz, F.; Schirmer, K.; Baity-Jesi, M.
10.1101/2023.05.27.542160 — bioinformatics — Posted on 2023-09-14
2818 Increased pulmonary monocyte infiltration and attenuated phagocytosis defines perinatal dysfunction of innate immunity in Cystic Fibrosis
Jaudas, F.; Bartenschlager, F.; Shashikadze, B.; Santamaria, G.; Schnell, A.; Naumann-Barsch, N.; Bruns, H.; Graeber, S. Y.; Baehr, A.; Cambra-Bort, M.; Stirm, M.; Stoeckl, J. B.; Krebs, S.; Blum, H.; Schulz, C.; Zawada, D.; Caballero-Posadas, I.; Kunzelmann, K.; Moretti, A.; Laugwitz, K.-L.; Kupatt, C.; Saalmueller, A.; Froehlich, T.; Wolf, E.; Mall, M. A.; Mundhenk, L.; Gerner, W.; Klymiuk, N.
10.1101/2023.09.11.556517 — immunology — Posted on 2023-09-14
2819 Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns
Baek, O.; Muk, T.; Wu, Z.; Ye, Y.; Khakimov, B.; Casano, A. M.; Gangadharan, B.; Bilic, I.; Brunse, A.; Sangild, P. T.; Nguyen, D. N.
10.1101/2023.09.11.557116 — immunology — Posted on 2023-09-14
2821 Multilevel regulation of NF-kappa B signaling by NSD2 suppresses Kras-driven pancreatic tumorigenesis
Feng, W.; Niu, N.; Lu, P.; Rao, H.; Chen, Z.; Zhang, W.; Ma, C.; Liu, C.; Xu, Y.; Gao, W.-Q.; Xue, J.; Li, L.
10.1101/2023.09.11.557111 — cancer biology — Posted on 2023-09-14
2822 Nucleoporin-binding nanobodies that either track or inhibit nuclear pore complex assembly
Görlich, D.; Colom, M. S.; Fu, Z.; Güttler, T.; Trakhanov, S.; Srinivasan, V.; Gregor, K.; Pleiner, T.
10.1101/2023.09.12.557426 — cell biology — Posted on 2023-09-14
2823 CD81 represses NF-?B in HCV-expressing hepatoma cells
Bunz, M.; Eisele, M.; Hu, D.; Ritter, M.; Kammerloher, J.; Lampl, S.; Schindler, M.
10.1101/2023.09.13.557511 — microbiology — Posted on 2023-09-14
2824 Microsporidia Ser/Thr Protein Phosphatase PP1 Targets DCs MAPK Pathway and Impair Immune Functions
Bao, J.; Tang, Y.; Chen, Y.; Jin, J.; Wang, X.; An, G.; Cao, L.; Zhang, H.; Cheng, G.; Pan, G.; Zhou, Z.
10.1101/2023.09.13.557560 — microbiology — Posted on 2023-09-14
2826 Programmed Cell Death Modifies Neural Circuits and Tunes Intrinsic Behavior
Kochersberger, A.; Torkashvand, M. M.; Lee, D.; Baskoylu, S.; Sengupta, T.; Koonce, N.; Emerson, C.; Patel, N. V.; Colon-Ramos, D.; Flavell, S. W.; Horvitz, H. R.; Venkatachalam, V.; Hammarlund, M.
10.1101/2023.09.11.557249 — neuroscience — Posted on 2023-09-14
2828 Endocannabinoid and psychological responses to acute resistance exercise in trained and untrained adults
Sirotiak, Z.; Gallagher, B. T.; Smith-Hernandez, C. A.; Showman, L. J.; Hillard, C. J.; Brellenthin, A. G.
10.1101/2023.09.08.556874 — physiology — Posted on 2023-09-14
2832 m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation
Klein, P.; Harley, J.; Crook, H.; Serna, S. E.; Roumeliotis, T. I.; Choudhary, J. S.; Chakrabarti, A. M.; Luisier, R.; Patani, R.; Ramos, A.
10.1101/2023.09.12.557394 — molecular biology — Posted on 2023-09-14
2834 B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters
Khan, S.; Chakraborty, M.; Wu, F.; Chen, N.; Wang, T.; Chan, Y. T.; Sayad, A.; Vasquez, J.-D. S.; Kotlyar, M.; Nguyen, K.; Huang, Y.; Alibhai, F. J.; Woo, M.; Li, R.-K.; Husain, M.; Jurisica, I.; Gehring, A. J.; Ohashi, P. S.; Furman, D.; Tsai, S.; Winer, S.; Winer, D. A.
10.1101/2023.09.12.556363 — immunology — Posted on 2023-09-14
2835 A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation
Ge, A. Y.; Arab, A.; Dai, R.; Navickas, A.; Fish, L.; Garcia, K.; Asgharian, H.; Keenan, K.; Pappalardi, M. B.; McCabe, M. T.; Przybyla, L.; Goodarzi, H.; Gilbert, L.
10.1101/2022.12.14.518457 — cancer biology — Posted on 2023-09-14
2836 Loss-of-function cancer-associated mutations in the EIF4G2 non-canonical translation initiation factor
Meril, S.; Bhalsen, M.; Eisenstein, M.; Savidor, A.; Levin, Y.; Bialik, S.; Pietrokovski, S.; Kimchi, A.
10.1101/2023.08.22.554280 — cancer biology — Posted on 2023-09-14
2838 Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging
Jakobsen, N. A.; Turkalj, S.; Zeng, A. G. X.; Stoilova, B.; Metzner, M.; Nagree, M. S.; Shah, S.; Moore, R.; Usukhbayar, B.; Salazar, M. A.; Gafencu, G.-A.; Kennedy, A.; Newman, S.; Kendrick, B. J. L.; Taylor, A. H.; Afinowi-Luitz, R.; Gundle, R.; Watkins, B.; Wheway, K.; Beazley, D.; Murison, A.; Aguilar-Navarro, A. G.; Flores-Figueroa, E.; Dakin, S. G.; Carr, A. J.; Nerlov, C.; Dick, J. E.; Xie, S. Z.; Vyas, P.
10.1101/2023.09.12.557322 — cancer biology — Posted on 2023-09-14
2839 Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer
Gedik, M. E.; Saatci, O.; Oberholtzer, N.; Uner, M.; Akbulut, O.; Cetin, M.; Aras, M.; Ibis, K.; Caliskan, B.; Banoglu, E.; Wiemann, S.; Uner, A.; Aksoy, S.; Mehrotra, S.; Sahin, O.
10.1101/2023.09.12.557273 — cancer biology — Posted on 2023-09-14
2840 Inhibiting Stromal Class I HDACs Curbs Pancreatic Cancer Progression
Liang, G.; Oh, T. G.; Hah, N.; Tiriac, H.; Shi, Y.; Truitt, M. L.; Antal, C. E.; Atkins, A. R.; Li, Y.; Fraser, C.; Ng, S.; Pinto, A. F.; Nelson, D. C.; Bashi, S.; Banayo, E.; Estepa, G.; Dai, Y.; Liddle, C.; Yu, R. T.; Hunter, T.; Engle, D.; Han, H.; Von Hoff, D. D.; Downes, M.; Evans, R. M.
10.1101/2023.09.12.557260 — cancer biology — Posted on 2023-09-14
2845 Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease
Wang, E.; Pan, A. L.; Bagchi, P.; Rangaraju, S.; Seyfried, N. T.; Ehrlich, M. E.; Salton, S. R.; Zhang, B.
10.1101/2023.09.13.557390 — bioinformatics — Posted on 2023-09-14
2846 Ultrasound-Mediated Drug-free Theranostics for Treatment of Prostate Cancer
Perera, R. H.; Berg, F. M.; Abenojar, E. C.; Nittayacharn, P.; Kim, Y.; Wang, X.; Basilion, J. P.; Exner, A. A.
10.1101/2023.09.13.555594 — bioengineering — Posted on 2023-09-14
2847 Single molecule long-read real-time amplicon-based sequencing of CYP2D6: a proof-of-concept with hybrid haplotypes
Dong, R.; Thamilselvan, M.; Foo, J. C.; DeJarnette, J.; Hu, X.; Carvalho Henriques, B.; Wang, Y.; Wallace, K.; Sivapalan, S.; Buchner, A.; Yavorskyy, V.; Martens, K.; Maier, W.; Henigsberg, N.; Hauser, J.; Cattaneo, A.; Mors, O.; Rietschel, M.; Pfeffer, G.; Aitchison, K. J.
10.1101/2022.08.17.503990 — genomics — Posted on 2023-09-14
2849 Decreased accuracy of forensic DNA mixture analysis for groups with lower genetic diversity
Flores, M.; Ly, C.; Ho, E.; Ceberio, N.; Felix, K.; Thorner, H. M.; Guardado, M.; Paunovich, M.; Godek, C.; Kalaydjian, C.; Rohlfs, R.
10.1101/2023.08.25.554311 — genetics — Posted on 2023-09-14
2852 Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice.
Sun, L.; Lv, Z.; Chen, X.; Ye, R.; Tian, S.; Wang, C.; Xie, X.; Yan, L.; Yao, X.; Shao, Y.; Cui, S.; Chen, J.; Liu, J.
10.1101/2023.06.21.545885 — developmental biology — Posted on 2023-09-14
2853 Defining the SPCA2C interactome identifies unique links to store-operated calcium entry
Samardzija, P.; Fenech, M. A.; Lang, R.; Carter, M. C.; Chen, S.; Shi, S.; Stathopulos, P. B.; Pin, C. L.
10.1101/2023.09.13.557610 — cell biology — Posted on 2023-09-14
2854 Deletion of exons 45 to 55 in the DMD gene: from the therapeutic perspective to the in vitro model
Poyatos-Garcia, J.; Soblechero-Martin, P.; Liquori, A.; Lopez-Martinez, A.; Gonzalez-Romero, E.; Vazquez-Manrique, R. P.; Muelas, N.; Garcia-Garcia, G.; Ohana, J.; Arechavala-Gomeza, V.; Vilchez, J. J.
10.1101/2023.09.13.557649 — cell biology — Posted on 2023-09-14
2858 Assessing The Impact Of Autologous Neutralizing Antibodies On Viral Rebound In Postnatally SHIV-Infected ART-Treated Infant Rhesus Macaques
Mainou, E.; Berendam, S. J.; Obregon-Perko, V.; Uffman, E. A.; Phan, C. T.; Shaw, G. M.; Bar, K. J.; Conway, J. M.; Chan, C.; Chahroudi, A. M.; McCarthy, J.; Permar, S. R.; Silvestri, G.; Siliciano, R. F.; Silicano, J.; Fouda, G. J.; Fray, E. J.; Kumar, M. R.
10.1101/2023.07.22.550159 — immunology — Posted on 2023-09-14
2859 The interplay between oxidative stress and inflammation supports autistic-related behaviors in mice
Pangrazzi, L.; Cerilli, E.; Balasco, L.; Tobia, C.; Dall'O', G. M.; Chelini, G.; Perini, S.; Filosi, M.; Ravizza, T.; Vezzani, A.; Provenzano, G.; Pastore, A.; Weinberger, B.; Domenici, E.; Bozzi, Y.
10.1101/2023.09.11.557109 — immunology — Posted on 2023-09-14
2860 Single-cell analysis of prenatal and postnatal human cortical development
Velmeshev, D.; Perez, Y.; Yan, Z.; Valencia, J. E.; Castaneda-Castellanos, D. R.; Wang, L.; Schirmer, L.; Mayer, S.; Wick, B.; Wang, S.; Nowakowski, T. J.; Paredes, M.; Huang, E. J. J.; Kriegstein, A.
10.1101/2022.10.24.513555 — neuroscience — Posted on 2023-09-14
2861 Decoding auditory working memory content from intracranial high frequency activity in humans
Uluc, I.; Peled, N.; Paulk, A. C.; Bush, A.; Gumenyuk, V.; Kotlarz, P. L.; Lankinen, K.; Mamashli, F.; Matsuda, N.; Richardson, M.; Stufflebeam, S. M.; Cash, S. S.; Ahveninen, J.
10.1101/2023.08.04.552073 — neuroscience — Posted on 2023-09-14
2867 Retracing Human Genetic Histories and Natural Selection Using Precise Local Ancestry Inference
Lerga-Jaso, J.; Novkovic, B.; Unnikrishnan, D.; Bamunusinghe, V.; Hatorangan, M.; Manson, C.; Pedersen, H.; Osama, A.; Terpolovsky, A.; Bohn, S.; De Marino, A.; Mahmoud, A.; Bircan, K.; Khan, U.; Grabherr, M.; Yazdi, P.
10.1101/2023.09.11.557177 — genomics — Posted on 2023-09-13
2868 SMARTdb: an integrated database for exploring single-cell multi-omics data of reproductive medicine
Liu, Z.; Yuan, Z.; Guo, Y.; Guan, Y.; Wang, R.; Wang, Z.; Chen, Y.; Wang, T.; Jiang, M.; Bian, S.
10.1101/2023.09.10.556986 — genomics — Posted on 2023-09-13
2869 Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox
Schertzer, M. D.; Stirn, A.; Isaev, K.; Pereira, L.; Das, A.; Harbison, C.; Park, S. H.; Wessels, H.-H.; Sanjana, N. E.; Knowles, D. A.
10.1101/2023.09.12.557474 — genomics — Posted on 2023-09-13
2870 Dmnt1 and Wnt in the production of oocytes
Cunningham, C.; Shelby, E. A.; McKinney, E. C.; Simmons, A. M.; Moore, A. J.; Moore, P. J.
10.1101/2023.09.13.557185 — genomics — Posted on 2023-09-13
2871 A mutation in Themis contributes to peanut-induced oral anaphylaxis in CC027 mice
Risemberg, E. L.; Smeekens, J. M.; Cruz-Cisneros, M. C.; Hampton, B. K.; Hock, P.; Linnertz, C. L.; Miller, D. R.; Orgel, K.; Shaw, G. D.; Pardo-Manuel de Villena, F.; Burks, A. W.; Valdar, W.; Kulis, M. D.; Ferris, M. T.
10.1101/2023.09.13.557467 — genetics — Posted on 2023-09-13
2872 Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome
Potel, C. M.; Burtscher, M. L.; Garrido-Rodriguez, M.; Brauer-Nikonow, A.; Becher, I.; Typas, A.; Zimmermann, M.; Savitski, M. M.
10.1101/2023.09.13.557529 — molecular biology — Posted on 2023-09-13
2875 In vivo selection in non-human primates identifies superior AAV capsids for on-target CSF delivery to spinal cord
Hanlon, K. S.; Cheng, M.; De La Cruz, D.; Patel, N.; Santoscoy, M. C.; Gong, Y.; Ng, C.; Nguyen, D. M.; Nammour, J.; Clark, S. W.; Kozarsky, K.; Maguire, C. A.
10.1101/2023.09.13.557506 — bioengineering — Posted on 2023-09-13
2876 Discovery of peptides for targeted delivery of mRNA lipid nanoparticles to cystic fibrosis lung epithelia
Soto, M. R.; Lewis, M. M.; Leal, J.; Pan, Y.; Mohanty, R. P.; Peng, X.; Dong, T.; Ghosh, D.
10.1101/2023.09.13.557559 — bioengineering — Posted on 2023-09-13
2878 APP substrate ectodomain defines A beta length by restraining gamma-secretase processivity and facilitating product release
Koch, M.; Enzlein, T.; Chen, S.-Y.; Petit, D.; Lismont, S.; Zacharias, M.; Hopf, C.; Chavez-Gutierrez, L.
10.1101/2023.09.13.557360 — biochemistry — Posted on 2023-09-13
2880 Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease
Thornton, M.; Sommer, N.; McGonigle, M.; Ram, A. K.; Yerrathota, S.; Ehirim, H.; Chaturvedi, A.; Dinh Phan, J.; Gunewardena, S.; Talreja, J.; Fields, T. A.; Ray, P. E.; Dhillon, N. K.; Sharma, M.
10.1101/2023.09.12.557484 — molecular biology — Posted on 2023-09-13
2881 The transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis and cytoplasmic decay
Kelbert,, M.; Jordan, A.; de-Miguel-Jimenez, L.; Garcia-Martinez, J.; Selitrennik, M.; Gutman,, A.; Henig,, N.; Granneman,, S.; Perez-Ortin, J. E.; Chavez, S.; Choder, M.
10.1101/2023.09.13.557510 — molecular biology — Posted on 2023-09-13
2882 The intrinsically disordered region of the E3 ubiquitin ligase TRIP12 induces the formation of chromatin condensates and interferes with DNA damage response.
Vargas, C.; Brunet, M.; Ricard, A.; varry, d.; Muzzopappa, F.; Erdel, F.; Labrousee, G.; Hanoun, N.; Ligat, L.; Farce, M.; Stella, A.; Burlet-Schiltz, O.; Laurell, H.; Bery, N.; Cordelier, P.; dufresne, m.; torrisani, j.
10.1101/2023.09.13.556486 — molecular biology — Posted on 2023-09-13
2883 Asgard archaea defense systems and their roles in the origin of immunity in eukaryotes
Leao, P.; Little, M. E.; Appler, K. E.; Sahaya, D.; Aguilar-Pine, E.; Currie, K.; Finkelstein, I. J.; De Anda, V.; Baker, B. J.
10.1101/2023.09.13.557551 — microbiology — Posted on 2023-09-13
2885 Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies
Ratnapriya, S.; Pothula, K. R.; Dam, K.-M. A.; Parthasarathy, D.; Benet, H. C.; Parsons, R.; Huang, X.; Sammour, S.; Janowska, K.; Harris, M.; Ahmed, S.; Sacco, S.; Sodroski, J.; Bridges, M.; Hubbell, W.; Acharya, P.; Herschhorn, A.
10.1101/2023.09.13.557082 — microbiology — Posted on 2023-09-13
2887 Inactivation of Highly Transmissible Livestock and Avian Viruses Including Influenza A and Newcastle Disease Virus for Molecular Diagnostics
Welch, J.; Shrestha, R.; Hutchings, H.; Pal, N.; Levings, R.; Robbe-Austerman, S.; Palinski, R.; Shanmuganatham, K.
10.1101/2023.09.13.557451 — microbiology — Posted on 2023-09-13
2889 Tissue-Specific Dependence of Th1 Cells on the Amino Acid Transporter SLC38A1 in Inflammation
Sugiura, A.; Beier, K.; Chi, C.; Heintzman, D.; Ye, X.; Wolf, M. M.; Cephus, J.-Y. C.; Hong, H.; Lyssiotis, C. A.; Newcomb, D. C.; Rathmell, J.
10.1101/2023.09.13.557496 — immunology — Posted on 2023-09-13
2890 Exogenous 4-1BB co-stimulation enhances memory B cell response during malaria.
Caloba, C.; Sturtz, A.; Ramachandran, A.; John, L.; Malkina, K.; Minns, A. M.; Lindner, S. E.; Vijay, R.
10.1101/2023.09.12.557411 — immunology — Posted on 2023-09-13
2891 Functional connectome through the human life span
Sun, L.; Zhao, T.; Liang, X.; Xia, M.; Li, Q.; Liao, X.; Gong, G.; Wang, Q.; Pang, C.; Yu, Q.; Bi, Y.; Chen, P.; Chen, R.; Chen, Y.; Chen, T.; Cheng, J.; Cheng, Y.; Cui, Z.; Dai, Z.; Deng, Y.; Ding, Y.; Dong, Q.; Duan, D.; Gao, J.-H.; Gong, Q.; Han, Y.; Han, Z.; Huang, C.-C.; Huang, R.; Li, L.; Lin, C.-P.; Lin, Q.; Liu, B.; Liu, C.; Liu, N.; Liu, Y.; Lu, J.; Ma, L.; Men, W.; Qin, S.; Qiu, J.; Qiu, S.; Si, T.; Tan, S.; Tang, Y.; Tao, S.; Wang, D.; Wang, F.; Wang, J.; Wang, P.; Wang, X.; Wang, Y.; Wei, D.; Wu, Y.; Xie, P.; Xu, X.; Xu, Y.; Xu, Z.; Yang, L.; Zeng, Z.; Zhang, H.; Zhang, X.; Zhao, G
10.1101/2023.09.12.557193 — neuroscience — Posted on 2023-09-13
2892 The reuniens nucleus of the thalamus facilitates hippocampo-cortical dialogue during sleep
Basha, D.; Azarmehri, A.; Proulx, E.; Chauvette, S.; Ghorbani, M.; Timofeev, I.
10.1101/2023.09.12.557350 — neuroscience — Posted on 2023-09-13
2893 Beta bursts question the ruling power for brain-computer interfaces
Papadopoulos, S.; Szul, M. J.; Congedo, M.; Bonaiuto, J. J.; Mattout, J.
10.1101/2023.09.11.557139 — neuroscience — Posted on 2023-09-13
2902 Reduced SV2A and GABAA receptor levels in the brains of type 2 diabetic rats revealed by flumazenil PET
Kong, Y.; Xie, F.; Wang, X.; Zuo, C.; Shi, K.; Rominger, A.; Huang, Q.; Xiao, J.; Jiang, D.; Guan, Y.; Ni, R.
10.1101/2023.09.10.557061 — neuroscience — Posted on 2023-09-13
2903 Adopting orphan receptors: group IX/X transition metals as potential ligands of zebrafish Tlr4 homologs
Fox, A. P. D.; Lee, T. S.; Mithaiwala, S. N.; Pollock, N. M.; Bhavsar, A. P.; Allison, W. T.
10.1101/2023.09.13.557392 — zoology — Posted on 2023-09-13
2907 Leucine zipper-based sorting system enables generation of multi-functional CAR T cells
James, S. E.; Chen, S.; Ng, B. D.; Fischman, J. S.; Jahn, L.; Boardman, A. P.; Rajagopalan, A.; Elias, H. K.; Massa, A.; Manuele, D.; Nichols, K. B.; Lazrak, A.; Lee, N.; Fei, T.; DeWolf, S.; Peled, J.; Vardhana, S. A.; Klebanoff, C. A.; van den Brink, M. R. M.
10.1101/2023.09.13.557232 — synthetic biology — Posted on 2023-09-13
2911 The tidyomics ecosystem: Enhancing omic data analyses
Hutchison, W. J.; Keyes, T. J.; Crowell, H. L.; Soneson, C.; Mu, W.; Park, J.-E.; Davis, E. S.; Nahid, A. A.; Tang, M.; Yuan, V.; Axisa, P.-P.; Kitt, J. W.; Poon, C.-L.; Sato, N.; Gottardo, R.; Morgan, M.; Lee, S.; Lawrence, M.; Hicks, S. C.; Nolan, G. P.; Davis, K. L.; Papenfuss, A. T.; Love, M. I.; Mangiola, S.
10.1101/2023.09.10.557072 — bioinformatics — Posted on 2023-09-13
2913 Microfabrication-based engineering of biomimetic dentin-like constructs to simulate dental aging
Alvarez, S.; Morales, J.; Tiozzo-Lyon, P.; Berrios, P.; Barraza, V.; Simpson, K.; Ravasio, A.; Vila, X. M.; Teuschl-Woller, A.; Schuh, C. M. A. P.; Aguayo, S.
10.1101/2023.09.10.557073 — bioengineering — Posted on 2023-09-13
2914 Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases
da Silva, J. F.; Tou, C. J.; King, E. M.; Eller, M. L.; Ma, L.; Rufino-Ramos, D.; Kleinstiver, B. P.
10.1101/2023.09.12.557440 — bioengineering — Posted on 2023-09-13
2915 The optimization of Salmonella surveillance programmes for pullet and layer farms using between-farm distance as a risk factor
Hobbelen, P.; Hagenaars, T. J.; Peri Markovich, M.; Bellaiche, M.; Giovannini, A.; De Massis, F.; de Koeijer, A.
10.1101/2023.09.10.557094 — ecology — Posted on 2023-09-13
2917 DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment
Hwang, R.-D.; Lu, Y.; Tang, Q.; Periz, G.; Park, G.; Li, X.; Liu, Y.; Zhang, T.; Wang, J.
10.1101/2023.09.12.556394 — neuroscience — Posted on 2023-09-13
2919 Adaptive multipole models of OPM data.
Tierney, T. M.; Seedat, Z.; St. Pier, K.; Mellor, S.; Barnes, G. R.
10.1101/2023.09.11.557150 — neuroscience — Posted on 2023-09-13
2923 Imputation of cell-type specific expression using RNA-seq data from mixed cell populations
Lin, W.-Y.; Kartawinata, M.; Jebson, B. R.; CLUSTER Consortium, ; Wedderburn, L. R.; Wallace, C.
10.1101/2023.09.11.556650 — bioinformatics — Posted on 2023-09-13
2924 Tree diversity increases forest temperature buffering
Schnabel, F.; Beugnon, R.; Yang, B.; Richter, R.; Eisenhauer, N.; Huang, Y.; Liu, X.; Wirth, C.; Cesarz, S.; Fichtner, A.; Perles-Garcia, M. D.; Hähn, G. J. A.; Härdtle, W.; Kunz, M.; Castro Izaguirre, N. C.; Niklaus, P. A.; von Oheimb, G.; Schmid, B.; Trogisch, S.; Wendisch, M.; Ma, K.; Bruelheide, H.
10.1101/2023.09.11.556807 — ecology — Posted on 2023-09-13
2928 Disease related changes in ATAC-Seq of more than 450 iPSC-derived motor neuron lines from ALS patients and controls
Tsitkov, S.; Valentine, K.; Kozareva, V.; Donde, A.; Frank, A.; Lei, S.; Answer ALS Consortium, ; Van Eyk, J.; Finkbeiner, S.; Rothstein, J.; Thompson, L.; Sareen, D.; Svendsen, C. N.; Fraenkel, E.
10.1101/2023.09.11.557005 — neuroscience — Posted on 2023-09-13
2929 Oligodendroglia generate vascular mural cells and neurons in the adult mouse brain
Yu, Q.; Yang, K.; Fan, Z.; Huang, M.; Xu, T.; Yang, Y.; Yang, Z.; He, X.; Yuan, F.
10.1101/2023.09.12.549127 — neuroscience — Posted on 2023-09-13
2930 Position-independent refinement of vagus motor neuron wiring
Kaneko, T.; Boulanger-Weill, J.; Isabella, A. J.; Moens, C. B.
10.1101/2023.09.11.557289 — neuroscience — Posted on 2023-09-13
2932 SKIN REINNERVATION BY COLLATERAL SPROUTING FOLLOWING SPARED NERVE INJURY IN MICE
Jeon, S.; Pradeep, A.; Chang, D.; McDonough, L.; Chen, Y.; Latremoliere, A.; Crawford, L. K.; Caterina, M. J.
10.1101/2023.09.12.557420 — neuroscience — Posted on 2023-09-13
2933 Hyperexcitability in human MECP2 null neuronal networks manifests as calcium-dependent reverberating super bursts
Pradeepan, K. S.; McCready, F. P.; Wei, W.; Khaki, M.; Zhang, W.; Salter, M. W.; Ellis, J.; Martinez-Trujillo, J. C.
10.1101/2023.09.12.557388 — neuroscience — Posted on 2023-09-13
2934 Chemogenetic activation of target neurons expressing insect Ionotropic Receptors in the mammalian central nervous system by systemic administration of ligand precursors
Iguchi, Y.; Fukabori, R.; Kato, S.; Takahashi, K.; Eifuku, S.; Maejima, Y.; Shimomura, K.; Mizuma, H.; Mawatari, A.; Doi, H.; Cui, Y.; Onoe, H.; Hikishima, K.; Osanai, M.; Nishijo, T.; Momiyama, T.; Benton, R.; Kobayashi, K.
10.1101/2023.09.11.557081 — neuroscience — Posted on 2023-09-13
2935 Synaptic and peptidergic connectomes of the Drosophila circadian clock
Reinhard, N.; Fukuda, A.; Manoli, G.; Derksen, E.; Saito, A.; Möller, G.; Sekiguchi, M.; Rieger, D.; Helfrich-Förster, C.; Yoshii, T.; Zandawala, M.
10.1101/2023.09.11.557222 — neuroscience — Posted on 2023-09-13
2938 Temporal dynamics of neural adaptation across human visual cortex
Brands, A. M.; Devore, S.; Devinsky, O.; Doyle, W.; Flinker, A.; Friedman, D.; Dugan, P.; Winawer, J.; Groen, I. I. A.
10.1101/2023.09.13.557378 — neuroscience — Posted on 2023-09-13
2941 Modeling the impact of genotype, age, sex, and continuous navigation on pathway integration performance
Pink, D.; Ilkel, E.; Chandreswaran, V.; Moser, D. A.; Getzmann, S.; Gajewski, P.; Axmacher, N.; Zhang, H.
10.1101/2023.09.11.556925 — neuroscience — Posted on 2023-09-13
2943 Sub-second Dopamine Signals during Risky Decision-Making in Patients with Impulse Control Disorder
Liebenow, B. N.; Wilson, T.; Maas, B.; Aladnani, E.; Moran, R. J.; White, J.; Lohrenz, T.; Haq, I. u.; Siddiqui, M. S.; Laxton, A. W.; Tatter, S. B.; Montague, P. R.; Kishida, K. T.
10.1101/2023.09.11.557178 — neuroscience — Posted on 2023-09-13
2945 Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus
Lee, J.; Zepeda, S.; Park, Y.-J.; Taylor, A. L.; Quispe, J.; Stewart, C.; Leaf, E. M.; Treichel, C.; Corti, D.; King, N. P.; Starr, T. N.; Veesler, D.
10.1101/2023.09.12.557371 — biochemistry — Posted on 2023-09-13
2946 Deep Learning disconnectomes to accelerate and improve long-term predictions for post-stroke symptoms
Matsulevits, A.; Coupe, P.; Nguyen, H.-D.; Talozzi, L.; Foulon, C.; Nachev, P.; Corbetta, M.; Tourdias, T.; Thiebaut de Schotten, M.
10.1101/2023.09.12.557396 — neuroscience — Posted on 2023-09-13
2948 Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal reward contingency signals during rule-reversal
Trejo, D. H.; Ciuparu, A.; Garcia da Silva, P.; Velasquez, C. M.; Rebouillat, B.; Gross, M. D.; Davis, M. B.; Muresan, R. C.; Albeanu, D. F.
10.1101/2023.09.12.557267 — neuroscience — Posted on 2023-09-13
2954 X chromosome encoded histone demethylase UTX regulates mammalian axon regeneration via microRNA-124
Yang, S.-G.; Wang, X.-W.; Li, C.-P.; Huang, T.; Li, Q.; Zhao, L.; Qian, C.; Saijilafu, ; Qian, J.; Liu, C.-M.; Zhou, F.-Q.
10.1101/2023.09.12.557354 — neuroscience — Posted on 2023-09-13
2955 Associations between maternal pre-pregnancy BMI and infant striatal mean diffusivity
Rosberg, A.; Merisaari, H.; Lewis, J. D.; Hashempour, N.; Lukkarinen, M.; Rasmussen, J. M.; Scheinin, N. M.; Karlsson, L.; Karlsson, H.; Tuulari, J. J.
10.1101/2023.09.11.557121 — neuroscience — Posted on 2023-09-13
2956 Rat Wetness Response: Sensory Cues, Behavior & Fur-based Drying
Triumph Attah, A.; Negron-Moreno, P.; Amigo-Duran, M.; Zhang, L.; Kenngott, M.; Brecht, M.; Clemens, A. M.
10.1101/2023.09.13.557175 — neuroscience — Posted on 2023-09-13
2958 Clinicopathologic Dissociation: Robust Lafora Body Accumulation in Malin KO Mice Without Observable Changes in Home-cage Behavior
Krishnan, V.; Wu, J.; Mazumder, A. G.; Kamen, J. L.; Adhyapak, N.; Schirmer, C.; Bass, J. S.; Lee, S. C.; Maheshwari, A.; Molinaro, G.; Gibson, J. R.; Huber, K. M.; Minassian, B. A.
10.1101/2023.09.11.557226 — neuroscience — Posted on 2023-09-13
2962 Three-dimensional markerless motion capture of multiple freely behaving monkeys for automated characterization of social behavior
Matsumoto, J.; Kaneko, T.; Kimura, K.; Negrete, S. B.; Guo, J.; Suda-Hashimoto, N.; Kaneko, A.; Morimoto, M.; Nishimaru, H.; Setogawa, T.; Go, Y.; Shibata, T.; Nishijo, H.; Takada, M.; Inoue, K.-i.
10.1101/2023.09.13.556332 — animal behavior and cognition — Posted on 2023-09-13
2968 Prenatal vitamin D deficiency alters immune cell proportions of young adult offspring through alteration of long-term stem cell fates
Ueda, K.; Chin, S. S.; Sato, N.; NIshikawa, M.; Yasuda, K.; Miyasaka, N.; Bera, B. S.; Chorro, L.; Dona-Termine, R.; Koba, W. R.; Reynolds, D.; Steidl, U. G.; Lauvau, G.; Greally, J. M.; Suzuki, M.
10.1101/2023.09.11.557255 — developmental biology — Posted on 2023-09-13
2972 mTORC1 Regulates the Metabolic Switch of Postnatal Cardiomyocytes During Regeneration
Paltzer, W. G.; Aballo, T. J.; Bae, J.; Hubert, K. A.; Nuttall, D. J.; Perry, C.; Wanless, K. N.; Nahlawi, R.; Ge, Y.; Mahmoud, A. I.
10.1101/2023.09.12.557400 — developmental biology — Posted on 2023-09-13
2973 Maternal IL-10 restricts fetal emergency myelopoiesis
Collins, A.; Swann, J. W.; Proven, M. A.; Patel, C.; Mitchell, C. A.; Kasbekar, M.; Dellorusso, P. V.; Passegue, E.
10.1101/2023.09.13.557548 — developmental biology — Posted on 2023-09-13
2975 BrainLM: A foundation model for brain activity recordings
Ortega Caro, J.; Oliveira Fonseca, A. H.; Averill, C.; Rizvi, S. A.; Rosati, M.; Cross, J. L.; Mittal, P.; Zappala, E.; Levine, D.; Dhodapkar, R. M.; Abdallah, C. G.; van Dijk, D.
10.1101/2023.09.12.557460 — neuroscience — Posted on 2023-09-13
2976 Crossmodal correspondence of natural amplitude modulations
Lemus, L.; Moran, I.; Melchor, J.; Figueroa, T.; Matta, M.; Cabrera, E.
10.1101/2023.09.13.557575 — neuroscience — Posted on 2023-09-13
2977 A robust measure of metacognitive sensitivity and confidence criteria
Arnold, D. H.; Clendinen, M.; Johnston, A.; Lee, A. L. F.; Yarrow, K.
10.1101/2023.09.12.557480 — neuroscience — Posted on 2023-09-13
2980 Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models
Thibaudeau, A.; Schmitt, K.; Francois, L.; Chatrousse, L.; Hoffmann, D.; Cousin, L.; Weiss, A.; Vuidel, A.; Jacob, C. B.; Sommer, P.; Benchoua, A.; Wilbertz, J. H.
10.1101/2023.09.13.557523 — neuroscience — Posted on 2023-09-13
2983 ATLAS: A rationally designed anterograde transsynaptic tracer
Rivera, J. F.; Weng, W.; Huang, H.; Rao, S.; Herring, B. E.; Arnold, D. B.
10.1101/2023.09.12.557425 — neuroscience — Posted on 2023-09-13
2985 Cross-species conservation in the regulation of parvalbumin by perineuronal nets
Wang, A. S.; Wan, X.; Storch, D.-S.; Cornez, G.; Balthazart, J.; Cisneros-Franco, J. M.; de Villers-Sidani, E.; Sakata, J.
10.1101/2023.09.13.557580 — neuroscience — Posted on 2023-09-13
2988 ATF4 Expression in Thermogenic Adipocytes is Required for Cold-Induced Thermogenesis in Mice via FGF21-Independent Mechanisms
Bjorkman, S. H.; Marti, A.; Jena, J.; Pena, L. M. G.; Weatherford, E. T.; Kato, K.; Koneru, J.; Chen, J. H.; Sood, A.; Potthoff, M. J.; Adams, C. M.; Abel, E. D.; Pereira, R. O.
10.1101/2023.03.09.531964 — physiology — Posted on 2023-09-13
2989 Contrasting roles of different mismatch repair proteins in basal-like breast cancer
Mo, J.; Borcherding, N.; Jo, S.; Tithi, T. I.; Cho, E.; Cash, C. E.; Honda, M.; Wang, L.; Ahmed, K. K.; Weigel, R.; Spies, M.; kolb, R.; Zhang, W.
10.1101/2023.07.20.549745 — cancer biology — Posted on 2023-09-13
2990 Protein phosphatase 1 regulates core PCP signaling
Song, S.; Cho, B.; Weiner, A. T.; Nissen, S. B.; Naharros, I. O.; Bosch, P. S.; Suyama, K.; Hu, Y.; He, L.; Svinkina, T.; Udeshi, N.; Carr, S. A.; Perrimon, N.; Axelrod, J. D.
10.1101/2023.09.12.556998 — developmental biology — Posted on 2023-09-13
2993 Hyperpolarization-Activated Currents Drive Neuronal Activation Sequences in Sleep
Mehrotra, D.; Levenstein, D.; Duszkiewicz, A. J.; Carrasco, S. S.; Booker, S. A.; Kwiatkowska, A.; Peyrache, A.
10.1101/2023.09.12.557442 — neuroscience — Posted on 2023-09-13
2995 Global brain activity and its coupling with cerebrospinal fluid flow is related to tau pathology
Han, F.; Lee, J.; Chen, X.; Ziontz, J.; Ward, T.; Landau, S.; Baker, S.; Harrison, T.; Jagust, W.
10.1101/2023.09.12.557492 — neuroscience — Posted on 2023-09-13
2997 Ancient origin of the rod bipolar cell pathway in the vertebrate retina
Hellevik, A. M.; Mardoum, P.; Hahn, J.; Kolsch, Y.; D'Orazi, F. D.; Suzuki, S. C.; Godinho, L.; Lawrence, O.; Rieke, F.; Shekhar, K.; Sanes, J. R.; Baier, H.; Baden, T.; Wong, R. O.; Yoshimatsu, T.
10.1101/2023.09.12.557433 — neuroscience — Posted on 2023-09-13
2998 Skeletal Muscle Phenotype-Specific Effects of ACVR1B and TGFBR1 Receptor Signalling on Muscle Transcriptome, Force generation and Metabolism
Shi, A.; Hillege, M. M. G.; Noort, W.; Offringa, C.; Wu, G.; Forouzanfar, T.; Hoogaars, W. M. H.; Wust, R. C. I.; Jaspers, R. T.
10.1101/2023.08.30.555466 — physiology — Posted on 2023-09-13
2999 G-PLIP: Knowledge graph neural network for structure-free protein-ligand bioactivity prediction
Crouzet, S. J.; Lieberherr, A. M.; Atz, K.; Nilsson, T.; Sach-Peltason, L.; Muller, A. T.; Dal Peraro, M.; Zhang, J. D.
10.1101/2023.09.01.555977 — bioinformatics — Posted on 2023-09-13
3000 The Origin And Speciation Of Orchids
Perez-Escobar, O. A.; Bogarin, D.; Przelomska, N. A.; Ackerman, J.; Balbuena, J. A.; Bellot, S.; Buehlmann, R. P.; Cabrera, B.; Cano, J. A.; Charitonidou, M.; Chomicki, G.; Clements, M. A.; Cribb, P.; Fernandez, M.; Flanagan, N. S.; Gravendeel, B.; Hagsater, E.; Halley, J. M.; Hu, A.-Q.; Jaramillo, C.; Mauad, A. V.; Maurin, O.; Muentz, R.; Leitch, I. J.; Li, L.; Negrao, R.; Oses, L.; Phillips, C.; Rincon, M.; Salazar Chavez, G.; Simpson, L.; Smidt, E.; Solano-Gomez, R.; Parra Sanchez, E.; Tremblay, R. L.; van den Berg, C.; Villanueva, B. S.; Zuluaga, A.; Chase, M. W.; Fay, M.; Condamine, F. L.
10.1101/2023.09.10.556973 — evolutionary biology — Posted on 2023-09-13
3001 The landscape of antibiotic resistance genes in the nasopharynx of preterm infants: Prolonged signature of hospitalization and effects by antibiotics
Dhariwal, A.; Rajar, P.; Salvadori, G.; Amdal, H. A.; Berild, D.; Saugstad, O. D.; Fugelseth, D.; Greisen, G.; Dahle, U.; Haaland, K.; Petersen, F. C.
10.1101/2023.08.09.552435 — microbiology — Posted on 2023-09-13
3002 Detection and characterization of novel luchacoviruses, genus Alphacoronavirus, shed in saliva and feces of meso-carnivores in the northeastern United States
Olarte-Castillo, X. A.; Plimpton, L. D.; McQueary, H. C.; Sun, Y.; Yu, Y. T.; Cover, S. C.; Richardson, A. N.; Jin, Y.; Grenier, J. K.; Cummings, K. J.; Bunting, E. M.; Diuk-Wasser, M.; Needle, D.; Schuler, K.; Stanhope, M. J.; Whittaker, G.; Goodman, L. B.
10.1101/2023.05.31.541188 — microbiology — Posted on 2023-09-13
3007 Majority of human circulating plasmablasts stop blasting: A probable misnomer
Nguyen, D. C.; Saney, C.; Hentenaar, I. T.; Cabrera-Mora, M.; Woodruff, M. C.; Andrews, J.; Lonial, S.; Sanz, I.; Lee, F. E.-H.
10.1101/2023.09.10.557057 — immunology — Posted on 2023-09-13
3008 Mouse models for pancreatic ductal adenocarcinoma are affected by the cre-driver used to promote KRASG12D activation.
Mousavi, F.; Thompson, J.; Lau, J.; Renollet, N.; Martin, M. B.; McGue, J.; Frankel, T.; Shooshtari, P.; Pin, C. L.; Bednar, F.
10.1101/2023.09.12.557383 — cancer biology — Posted on 2023-09-13
3012 Evidence for the cardiodepressive effects of the plasticizer di-2-ethylhexylphthalate (DEHP)
Swift, L. M.; Roberts, A.; Pressman, J.; Guerrelli, D.; Allen, S.; Haq, K.; Reisz, J.; D'Alessandro, A.; Posnack, N. G.
10.1101/2023.05.22.541729 — pharmacology and toxicology — Posted on 2023-09-13
3013 The Effect of Mechanical Stimuli on the Phenotypic Plasticity of Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells in a 3D Hydrogel
Meijer, E. M.; Giles, R.; van Dijk, C. G. M.; Maringanti, R.; Wissing, T. B.; Appels, Y.; Chrifi, I.; Crielaard, H.; Verhaar, M. C.; Smits, A. I.; Cheng, C.
10.1101/2023.09.11.557280 — cell biology — Posted on 2023-09-13
3014 Quantitative label free mass spectrometry reveals content and signaling differences between neonatal and adult platelets
Thom, C. S.; Davenport, P.; Fazelinia, H.; Liu, Z.-J.; Zhang, H.; Ding, H.; Roof, J.; Spruce, L. A.; Ischiropoulos, H.; Sola-Visner, M.
10.1101/2023.09.13.557268 — cell biology — Posted on 2023-09-13
3015 Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
Papandreou, A.; Singh, N.; Gianfrancesco, L.; Budinger, D.; Barwick, K.; Agrotis, A.; Luft, C.; Shao, Y.; Lenaerts, A.-S.; Gregory, A.; Jeong, S. Y.; Hogarth, P.; Hayflick, S.; Barral, S.; Kriston-Vizi, J.; Gissen, P.; Kurian, M. A. A.; Ketteler, R.
10.1101/2023.09.13.556416 — cell biology — Posted on 2023-09-13
3016 Growth factor-induced desialylation for the fast control of endocytosis
MacDonald, E.; Forrester, A.; Valades-Cruz, C. A.; Madsen, T. D.; Hetmanski, J.; Dransart, E.; Ng, Y.; Godbole, R.; Akhil Shp, A.; Leconte, L.; Chambon, V.; Ghosh, D.; Pinet, A.; Bhatia, D. D.; Lombard, B.; Loew, D.; Larsen, M. R.; Leffler, H.; Lefeber, D.; Clausen, H.; Caswell, P. T.; Shafaq-Zadah, M.; Mayor, S.; Weigert, R.; Wunder, C.; Johannes, L.
10.1101/2023.09.12.557183 — cell biology — Posted on 2023-09-13
3017 Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells
Winer, B. Y.; Settle, A. H.; Yakimov, A. M.; Jeronimo, C.; Lazarovt, T.; Tipping, M.; Saoi, M.; Sawh, A.; Sepp, A.-L. L.; Galiano, M.; Perry, J. S. A.; Wong, Y. Y.; Geissmann, F.; Cross, J.; Zhou, T.; Kam, L. C.; Pasoli, H. A.; Hohl, T.; Cyster, J. G.; Weiner, O.; Huse, M.
10.1101/2023.09.12.556572 — cell biology — Posted on 2023-09-13
3021 A novel kit mutant rat enables hematopoietic stem cell engraftment without irradiation
IIDA, R.; ISHIDA, S.; WANG, J.; HATTORI, K.; YOSHIMI, K.; YAMAZAKI, S.; Mashimo, T.
10.1101/2023.09.12.556153 — cell biology — Posted on 2023-09-13
3022 NOC1 is a Direct MYC Target, and Its Protein Interactome Dissects Its Activity in Controlling Nucleolar Function
Manara, V.; Radoani, M.; Belli, R.; Peroni, D.; Destefanis, F.; Angheben, L.; Tome, G.; Tebaldi, T.; bellosta, p.
10.1101/2023.09.12.557489 — cell biology — Posted on 2023-09-13
3023 Competition and Synergy of Arp2/3 and Formins in Nucleating Actin Waves
Chua, X. L.; Tong, C. S.; Xu, X. J.; Su, M.; Xiao, S.; Wu, X.; Wu, M.
10.1101/2023.09.13.557508 — cell biology — Posted on 2023-09-13
3025 Cep290 is cooperatively maintained at basal body by Cep131-Cep162 and Cby-Fam92 modules
Wu, Z.; Chen, H.; Zhang, Y.; Wang, Y.; Wang, Q.; Augiere, C.; Hou, Y.; Fu, Y.; Peng, Y.; Durand, B.; Wei, Q.
10.1101/2023.09.12.557303 — cell biology — Posted on 2023-09-13
3026 A hematopoietic stem cell subset that retains memory of prior inflammatory stress accumulates in aging and clonal hematopoiesis
Zeng, A. G. X.; Nagree, M. S.; Jakobsen, N. A.; Shah, S.; Murison, A.; Cheong, J.-G.; Lim, I.; Jin, L.; Aguilar-Navarro, A. G.; Araujo, J.; Parris, D.; McLeod, J.; Kim, H.; Lee, H.; Zhang, L.; Boulanger, M.; Wagenblast, E.; Flores-Figueroa, E.; Wang, B.; Schwartz, G. W.; Josefowicz, S. Z.; Vyas, P.; Dick, J. E.; Xie, S. Z.
10.1101/2023.09.11.557271 — cell biology — Posted on 2023-09-13
3028 Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson's disease
Ferreira, S. A.; Li, C.; Klaestrup, I. H.; Vitic, Z.; Toft, G. U.; Betzer, C.; Svedsen, P.; Jensen, P. H.; Luo, Y.; Etzerodt, A.; Moestrup, S. K.; Romero-Ramos, M.
10.1101/2022.10.17.512526 — neuroscience — Posted on 2023-09-13
3029 High-throughput feedback-enabled optogenetic stimulation and spectroscopy in microwell plates
Benman, W.; Datta, S.; Gonzalez-Martinez, D.; Lee, G.; Hooper, J.; Qian, G.; Leavitt, G.; Salloum, L.; Ho, G.; Mhatre, S.; Magaraci, M. S.; Patterson, M.; Mannickarottu, S. G.; Malani, S.; Avalos, J. L.; Chow, B. Y.; Bugaj, L. J.
10.1101/2022.07.13.499906 — synthetic biology — Posted on 2023-09-13
3033 Validation of hypermethylated DNA regions found in colorectal cancers as potential aging-independent biomarkers of precancerous colorectal lesions
Sajibu, S.; Sonder, E.; Tiwari, A.; Orjuela, S.; Parker, H. R. D.; The Frans, O.; Gubler, C.; Marra, G.; Robinson, M. D.
10.1101/2023.05.24.542159 — genomics — Posted on 2023-09-13
3034 The Origin And Speciation Of Orchids
Perez-Escobar, O. A.; Bogarin, D.; Przelomska, N. A.; Ackerman, J.; Balbuena, J. A.; Bellot, S.; Buehlmann, R. P.; Cabrera, B.; Cano, J. A.; Charitonidou, M.; Chomicki, G.; Clements, M. A.; Cribb, P.; Fernandez, M.; Flanagan, N. S.; Gravendeel, B.; Hagsater, E.; Halley, J. M.; Hu, A.-Q.; Jaramillo, C.; Mauad, A. V.; Maurin, O.; Muentz, R.; Leitch, I. J.; Li, L.; Negrao, R.; Oses, L.; Phillips, C.; Rincon, M.; Salazar Chavez, G.; Simpson, L.; Smidt, E.; Solano-Gomez, R.; Parra Sanchez, E.; Tremblay, R. L.; van den Berg, C.; Villanueva, B. S.; Zuluaga, A.; Chase, M. W.; Fay, M.; Condamine, F. L.
10.1101/2023.09.10.556973 — evolutionary biology — Posted on 2023-09-13
3038 A multi-hierarchical approach reveals D-serine as a hidden substrate of sodium-coupled monocarboxylate transporters
Wiriyasermkul, P.; Moriyama, S.; Suzuki, M.; Kongpracha, P.; Nakamae, N.; Takeshita, S.; Tanaka, Y.; Matsuda, A.; Miyasaka, M.; Hamase, K.; Kimura, T.; Mita, M.; Sasabe, J.; Nagamori, S.
10.1101/2020.08.10.244822 — biochemistry — Posted on 2023-09-13
3040 Polymorphic short tandem repeats make widespread contributions to blood and serum traits
Margoliash, J.; Fuchs, S.; Li, Y.; Zhang, X.; Massarat, A.; Goren, A.; Gymrek, M.
10.1101/2022.08.01.502370 — genetics — Posted on 2023-09-13
3042 Mitochondrial transplantation and its impact on infectious disease progression: a pilot study
Benson, T.; Patel, S. P.; Albensi, B. C.; Mahajan, V. B.; Adlimoghaddam, A.; Sikora, S.; Saito, H.
10.1101/2023.09.08.556161 — molecular biology — Posted on 2023-09-13
3043 Synovial Sarcoma X Breakpoint 1 Protein uses a cryptic groove to selectively recognize H2AK119Ub Nucleosomes
Tong, Z.; Ai, H.; Xu, Z.; He, K.; Chu, G.-c.; Shi, Q.; Deng, Z.; Xue, Q.; Sun, M.; Du, Y.; Liang, L.; Li, J.-B.; Pan, M.; LIU, L.
10.1101/2023.07.08.548231 — molecular biology — Posted on 2023-09-13
3046 The influence of chronological age and menopause status on the functional neural correlates of spatial context memory in middle-aged females.
Crestol, A.; Rajagopal, S.; Lissaman, R.; LaPlume, A.; Pasvanis, S.; Olsen, R.; Einstein, G.; Jacobs, E. G.; Rajah, M. N.
10.1101/2023.09.06.556387 — neuroscience — Posted on 2023-09-13
3047 Unilateral hippocampal stroke in freely behaving mice reveals sex differences in contralesional spreading depolarization and associated behavior
Boyce, A. K.; Fouad, Y.; Gom, R. C.; Martins-Silva, C.; Molina, L.; Fuzesi, T.; Ens, C.; Nicola, W.; Teskey, G. C.; Thompson, R. J.
10.1101/2023.08.31.555814 — neuroscience — Posted on 2023-09-13
3048 Top-down control of flight by a non-canonical cortico-amygdala pathway.
Borkar, C. D.; Fu, X.; Stelly, C. E.; Dorofeikova, M.; Le, Q.-S. E.; Vutukuri, R.; Vo, C.; Basavanhalli, S.; Duong, A.; Bean, E.; Resendez, A.; Parker, J. G.; Tasker, J. G.; Fadok, J. P.
10.1101/2022.05.19.492688 — neuroscience — Posted on 2023-09-13
3050 Unpacking the functional heterogeneity of the Emotional Face Matching Task: a normative modelling approach
Savage, H. S.; Mulders, P. C. R.; van Eijndhoven, P. F. P.; van Oort, J.; Tendolkar, I.; Vrijsen, J. N.; Beckmann, C. F.; Marquand, A. F.
10.1101/2023.03.27.534351 — neuroscience — Posted on 2023-09-13
3051 Developmental pyrethroid exposure disrupts molecular pathways for circadian rhythms and synaptic plasticity in mouse brain.
Nguyen, J. H.; Curtis, M. A.; Imami, A. S.; Ryan, W. G.; Alganem, K.; Neifer, K. L.; Saferin, N.; Nawor, C. N.; Kistler, B. P.; Miller, G. W.; Shukla, R.; McCullumsmith, R. E.; Burkett, J. P.
10.1101/2023.08.28.555113 — neuroscience — Posted on 2023-09-13
3056 Effects of Food Addition and Helminth Removal on Space Use and Spatial Overlap in Wild Rodent Populations
Mistrick, J.; Kitchen, S. M.; Veitch, J. S. M.; Clague, S.; Newman, B. C.; Hall, R. J.; Budischak, S. A.; Forbes, K. M.; Craft, M. E.
10.1101/2022.12.22.521674 — ecology — Posted on 2023-09-13
3057 A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification
Nano, P. R.; Fazzari, E.; Azizad, D.; Nguyen, C. V.; Wang, S.; Kan, R. L.; Wick, B.; Haeussler, M.; Bhaduri, A.
10.1101/2023.09.12.557406 — developmental biology — Posted on 2023-09-13
3058 Cerebellar granule cell migration and folia development requires Mllt11/Af1q
Blommers, M.; Stanton-Turcotte, D.; Witt, E. A.; Heidari, M.; Iulianella, A.
10.1101/2023.09.12.557458 — developmental biology — Posted on 2023-09-13
3059 Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency
Zenk, F.; Fleck, J. S.; Jansen, S. M. J.; Kashanian, B.; Eisinger, B.; Santel, M.; Dupre, J. S.; Camp, G.; Treutlein, B.
10.1101/2023.09.12.557341 — developmental biology — Posted on 2023-09-13
3061 m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation
Klein, P.; Harley, J.; Crook, H.; Serna, S. E.; Roumeliotis, T. I.; Choudhary, J. S.; Chakrabarti, A. M.; Luisier, R.; Patani, R.; Ramos, A.
10.1101/2023.09.12.557394 — molecular biology — Posted on 2023-09-12
3062 Ether phospholipids modulate somatosensory responses by tuning multiple receptor functions in Drosophila
SUITO, T.; Nagao, K.; Deng, X.; Ganser, C.; Uchihashi, T.; Tsutsumi, M.; Nemoto, T.; Hara, Y.; Tominaga, M.; Sokabe, T.
10.1101/2023.09.12.556286 — molecular biology — Posted on 2023-09-12
3063 HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa
Windels, E. M.; Wampande, E. M.; Joloba, M. L.; Boom, W. H.; Goig, G. A.; Cox, H.; Hella, J.; Borrell, S.; Gagneux, S.; Brites, D.; Stadler, T.
10.1101/2023.09.12.557301 — microbiology — Posted on 2023-09-13
3064 Serial attentional resource allocation during parallel feature value tracking
Merkel, C.; Burgmann, L.; Bartsch, M. V.; Schoenfeld, M. A.; Hopf, J.-M.
10.1101/2023.09.12.557201 — neuroscience — Posted on 2023-09-13
3065 A comparison of telencephalon composition among chickens, junglefowl, and wild galliforms.
Racicot, K. J.; Ham, J. R.; Augustine, J.; Henriksen, R.; Wright, D.; Iwaniuk, A. N.
10.1101/2023.09.10.557096 — neuroscience — Posted on 2023-09-13
3067 Neuronal correlates of time integration into memories
Frantzmann, F.; Lamberty, M.; Braune, L.; Auger, G. M.; Chouhan, N. S.; Langenhan, T.; Selcho, M.; Pauls, D.
10.1101/2023.09.12.557375 — neuroscience — Posted on 2023-09-13
3069 Dual lineage origins of neocortical astrocytes
Zhou, J.; Vitali, I.; Roig Puiggros, S.; Javed, A.; Jabaudon, D.; Mayer, C.; Bocchi, R.
10.1101/2023.09.12.557313 — neuroscience — Posted on 2023-09-13
3070 A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma
Rey, V.; Tornin, J.; Alba-Linares, J. J.; Robledo, C.; Murillo, D.; Rodriguez, A.; Gallego, B.; Huergo, C.; Brana, A.; Astudillo, A.; Heymann, D.; Fernandez, A. F.; Fraga, M. F.; Alonso, J.; Rodriguez, R.
10.1101/2023.09.12.557334 — cancer biology — Posted on 2023-09-12
3071 Discovery of specific activity of 2-HPA acting on the membrane progestin receptor α (paqr7) by purification of natural products from the marine algae Padina
Amin, M. T.; Acharjee, M.; Jyoti, M. M. S.; Rezanujjaman, M.; Hassan, M. M.; Hossain, M. F.; Ahamed, S.; Kodani, S.; Tokumoto, T.
10.1101/2023.09.12.557470 — biochemistry — Posted on 2023-09-12
3073 Septoria tritici blotch resistance gene Stb15 encodes a lectin receptor-like kinase
Hafeez, A. N.; Chartrain, L.; Cong, F.; Cambon, F.; Clarke, M.; Griffiths, S.; Hayta, S.; Jiang, M.; Keller, B.; Kirby, R.; Kolodziej, M. C.; Powell, O. R.; Smedley, M.; Steuernagel, B.; Xian, W.; Wingen, L. U.; Cheng, S.; Saintenac, C.; Wulff, B. B. H.; Brown, J. K. M.
10.1101/2023.09.11.557217 — genetics — Posted on 2023-09-12
3076 KRASG12D-mediated PanIN progression in mice is affected by gene driving cre recombinase expression
Mousavi, F.; Thompson, J.; Lau, J.; Renollet, N.; Martin, M. B.; McGue, J.; Frankel, T.; Shooshtari, P.; Pin, C. L.; Bednar, F.
10.1101/2023.09.12.557383 — cancer biology — Posted on 2023-09-12
3083 ENHANCED EFFICIENCY OF RNA-GUIDED CAS12a VERSUS CAS9 TRANSGENE KNOCK-IN AND ACTIVITY AT A SCHISTOSOMA MANSONI GENOME SAFE HARBOR
Moescheid, M. F.; Wisitphongpun, P.; Mann, V. H.; Quack, T.; Grunau, C.; Grevelding, C. G.; Tanno, W. I.; Brindley, P. J.
10.1101/2023.09.12.557428 — molecular biology — Posted on 2023-09-12
3085 ATP burst is the dominant driver of antibiotic lethality in Mycobacteria
Lodhiya, T.; Palande, A.; Veeram, A.; Larrouy-Maumus, G.; Beste, D. J.; Mukherjee, R.
10.1101/2023.09.11.557291 — microbiology — Posted on 2023-09-12
3089 An obligate aerobe adapts to hypoxia by hybridising fermentation with carbon storage
Gillett, D. L.; Hutchinson, T.; Mudaliyar, M.; Watts, T. D.; Wong, W. W.; Locop, J.; Jimenez, L.; Hanchapola, I.; Lee, H.-C.; Tanuwidjaya, E.; Steele, J. R.; Schittenhelm, R. B.; Barlow, C.; Grinter, R.; Ghosal, D.; Cook, P.; Greening, C.
10.1101/2023.09.11.557286 — microbiology — Posted on 2023-09-12
3092 Insight into spatial intratumoral genomic evolution in glioblastoma
Anand, A.; Petersen, J. K.; Andersen, L. v. B.; Burton, M.; Larsen, M. J.; Pedersen, C. B.; Poulsen, F. R.; Grupe, P.; Kruse, T. A.; Thomassen, M.; Kristensen, B. W.
10.1101/2023.09.11.557112 — cancer biology — Posted on 2023-09-12
3094 Conformation Selection by ATP-competitive Inhibitors and Allosteric Communication in ERK2
Anderson, J. W.; Vaisar, D.; Jones, D. N.; Pegram, L. M.; Chen, H.; Moffat, J. G.; Ahn, N. G.
10.1101/2023.09.12.557258 — biochemistry — Posted on 2023-09-12
3096 The Interactome of DUX4 Reveals Multiple Activation Pathways
Slavin, M.; Zohar, K.; Claus, C.; Schneidman-Duhovny, D.; Linial, M.; Coppee, F.; Kalisman, N.
10.1101/2023.09.12.557395 — biochemistry — Posted on 2023-09-12
3097 Whole Genome Sequencing Based Analysis of Inflammation Biomarkers in the Trans-Omics for Precision Medicine (TOPMed) Consortium
Jiang, M.-Z.; Gaynor, S. M.; Li, X.; Van Buren, E.; Stilp, A.; Buth, E.; Wang, F. F.; Manansala, R.; Gogarten, S. M.; Li, Z.; Polfus, L. M.; Salimi, S.; Bis, J. C.; Pankratz, N.; Yanek, L. R.; Durda, P.; Tracy, R. P.; Rich, S. S.; Rotter, J. I.; Mitchell, B. D.; Lewis, J. P.; Psaty, B. M.; Pratte, K. A.; Silverman, E. K.; Kaplan, R. C.; Avery, C.; North, K.; Mathias, R. A.; Faraday, N.; Lin, H.; Wang, B.; Carson, A. P.; Norwood, A. F.; Gibbs, R. A.; Kooperberg, C.; Lundin, J.; Peters, U.; Dupuis, J.; Hou, L.; Fornage, M.; Benjamin, E. J.; Reiner, A. P.; Bowler, R. P.; Lin, X.; Auer, P. L.; Raf
10.1101/2023.09.10.555215 — genetics — Posted on 2023-09-12
3099 Winners and losers under past and future climate change
Thomas, A. E.; Larcombe, M. J.; Higgins, S. I.; Trabucco, A.; Tanentzap, A. J.
10.1101/2023.09.11.556540 — ecology — Posted on 2023-09-12
3102 Protein generation with evolutionary diffusion: sequence is all you need
Alamdari, S.; Thakkar, N.; van den Berg, R.; Lu, A. X.; Fusi, N.; Amini, A. P.; Yang, K. K.
10.1101/2023.09.11.556673 — bioengineering — Posted on 2023-09-12
3105 Tissue-scale dynamic mapping of Hematopoietic Stem Cells and supportive niche cells in the fetal liver
Helbling, P. M.; Vijaykumar, A.; Gomariz, A.; Zielinska, K. A.; Zerkatje, T.; Loosli, K.; Isringhausen, S.; Nagasawa, T.; Roeder, I.; Manz, M. G.; Yokomizo, T.; Nombela-Arrieta, C.
10.1101/2023.09.12.554625 — developmental biology — Posted on 2023-09-12
3107 Immune Evasion, Infectivity, and Fusogenicity of SARS-CoV-2 Omicron BA.2.86 and FLip Variants
Qu, P.; Xu, K.; Faraone, J. N.; Goodarzi, N.; Zheng, Y.-M.; Carlin, C.; Bednash, J. S.; Horowitz, J. C.; Mallampalli, R. K.; Saif, L. J.; Oltz, E. M.; Jones, D.; Gumina, R. J.; Liu, S.-L.
10.1101/2023.09.11.557206 — microbiology — Posted on 2023-09-12
3108 Compartmentalized SARS-CoV-2 replication in upper versus lower respiratory tract after intranasal inoculation or aerosol exposure
Fischer, R.; Bushmaker, T.; Williamson, B. N.; Perez-Perez, L.; Feldmann, F.; Lovaglio, J.; Scott, D.; Saturday, G.; Feldmann, H.; Munster, V. J.; de Wit, E.; van Doremalen, N.
10.1101/2023.09.11.557190 — microbiology — Posted on 2023-09-12
3110 Dual inhibition of coronavirus Mpro and PLpro enzymes by phenothiazines and their antiviral activity
Forrestall, K. L.; Pringle, E. S.; Sands, D.; Duguay, B.; Farewell, B.; Woldemariam, T.; Falzarano, D.; Pottie, I. R.; McCormick, C.; Darvesh, S.
10.1101/2023.09.11.557219 — microbiology — Posted on 2023-09-12
3111 Concurrent administration of COVID-19 and influenza vaccines enhances Spike-specific antibody responses
Barouch, S. E.; Chicz, T. M.; Blanc, R.; Barbati, D. R.; Parker, L. J.; Tong, X.; McNamara, R. P.
10.1101/2023.09.12.557347 — immunology — Posted on 2023-09-12
3116 Knockout of the longevity gene Klotho perturbs aging- and Alzheimer's disease-linked brain microRNAs and tRNA fragments
Dubnov, S.; Yayon, N.; Yakov, O.; Bennett, D. A.; Seshadri, S.; Mufson, E.; Tzur, Y.; Bennett, E. R.; Greenberg, D.; Kuro-o, M.; Paldor, I.; Abraham, C. R.; Soreq, H.
10.1101/2023.09.10.557032 — neuroscience — Posted on 2023-09-12
3117 Beyond pulsed inhibition: Alpha oscillations modulate attenuation and amplification of neural activity in the awake resting-state
Lombardi, F.; Herrmann, H. J.; Parrino, L.; Plenz, D.; Scarpetta, S.; Vaudano, A. E.; de Arcangelis, L.; Shriki, O.
10.1101/2022.03.03.482657 — neuroscience — Posted on 2023-09-12
3121 Gas tunnel engineering of prolyl hydroxylasereprograms hypoxia signaling in cells
Windsor, P.; Ouyang, H.; da Costa, J. A. G.; Damodaran, A. R.; Chen, Y.; Bhagi-Damodaran, A.
10.1101/2023.08.07.552357 — biochemistry — Posted on 2023-09-12
3123 Sterol 3-beta-Glucosyltransferase TRANSPARENT TESTA15 Controls Seed Development and Flavanol Accumulation through its Role in Vacuole Biogenesis and Maintenance in Arabidopsis
Akary, E.; Berger, A.; Perreau, F.; Frey, A.; To, A.; Citerne, S.; Schaller, H.; Vernhettes, S.; Grandjean, O.; Nesi, N.; Marion-Poll, A.; Lepiniec, L.; Debeaujon, I.
10.1101/2023.09.12.557332 — plant biology — Posted on 2023-09-12
3125 A novel workflow for unbiased quantification of autophagosomes in 3D in Arabidopsis thaliana roots
Danek, M.; Kocourkova, D.; Podmanicka, T.; Eliasova, K.; Nesvadbova, K.; Krupar, P.; Martinec, J.
10.1101/2023.09.11.557125 — plant biology — Posted on 2023-09-12
3126 Carotenoid metabolism negatively regulates auxin-mediated root growth
Xu, K.; Zeng, H.; Yumoto, E.; Asahina, M.; Hayashi, K.-i.; Fukaki, H.; Ito, H.; Watahiki, M. K.
10.1101/2023.09.12.555306 — plant biology — Posted on 2023-09-12
3127 Linking genomic prediction for muscle fat content in Atlantic salmon to underlying changes in lipid metabolism regulation
Harvey, T. N.; Dvergedal, H.; Gronvold, L.; Jin, Y.; Odegard, J.; Korsvoll, S. A.; Knutsen, T. M.; Hvidsten, T. R.; Sandve, S. R.
10.1101/2023.08.29.555338 — genomics — Posted on 2023-09-12
3135 The Origin And Speciation Of Orchids
Perez-Escobar, O. A.; Bogarin, D.; Przelomska, N. A.; Ackerman, J.; Balbuena, J. A.; Bellot, S.; Buehlmann, R. P.; Cabrera, B.; Cano, J. A.; Charitonidou, M.; Chomicki, G.; Clements, M. A.; Cribb, P.; Fernandez, M.; Flanagan, N. S.; Gravendeel, B.; Hagsater, E.; Halley, J. M.; Hu, A.-Q.; Jaramillo, C.; Mauad, A. V.; Maurin, O.; Muentz, R.; Leitch, I. J.; Li, L.; Negrao, R.; Oses, L.; Phillips, C.; Rincon, M.; Salazar Chavez, G.; Simpson, L.; Smidt, E.; Solano-Gomez, R.; Parra Sanchez, E.; Tremblay, R. L.; van den Berg, C.; Villanueva, B. S.; Zuluaga, A.; Chase, M. W.; Fay, M.; Condamine, F. L.
10.1101/2023.09.10.556973 — evolutionary biology — Posted on 2023-09-12
3137 The colocatome as a spatial -omic reveals shared microenvironment features between tumour-stroma assembloids and lung cancer specimens
Bouchard, G.; Zhang, W.; Li, I.; Ilerten, I.; Shrager, J. B.; Bhattacharya, A.; Li, Y.; Trope, W.; Osawa, M. G.; Kuo, C.; Tian, L.; Giaccia, A. J.; Plevritis, S. K.
10.1101/2023.09.11.557278 — bioengineering — Posted on 2023-09-12
3138 Targeting monocytic Occludin impairs monocyte transmigration and HIV neuroinvasion
Brychka, D.; Ayala-Nunez, N. V.; Bare, Y.; Dupas, A.; Partiot, E.; Mittelheisser, V.; Lucansky, V.; Goetz, J. G.; Osmani, N.; Gaudin, R.
10.1101/2023.09.11.557242 — cell biology — Posted on 2023-09-12
3139 Sleep-dependent engram reactivation during hippocampal memory consolidation is associated with subregion-specific biosynthetic changes
Wang, L.; Park, L.; Wu, W.; King, D.; Medina, A. V.; Raven, F.; Martinez, J. D.; Ensing, A.; McDonald, K.; Yang, Z.; Jiang, S.; Aton, S.
10.1101/2022.11.09.515837 — neuroscience — Posted on 2023-09-12
3142 Myosin-binding protein C forms C-links and stabilizes OFF states of myosin
Hessel, A. L.; Engels, N. M.; Kuehn, M.; Nissen, D.; Sadler, R. L.; Ma, W.; Irving, T. C.; Linke, W. A.; Harris, S. P.
10.1101/2023.09.10.556972 — physiology — Posted on 2023-09-12
3145 Structure-based discovery of CFTR potentiators and inhibitors
Liu, F.; Kaplan, A. L.; Levring, J.; Einsiedel, J.; Tiedt, S.; Distler, K.; Omattage, N.; Kondratov, I. S.; Moroz, Y. S.; Pietz, H. L.; Irwin, J. J.; Gmeiner, P.; Shoichet, B. K.; Chen, J.
10.1101/2023.09.09.557002 — biophysics — Posted on 2023-09-12
3146 In Silico Analysis of Drug Off-Target Effects on Diverse Isoforms of Cervical Cancer for Enhanced Therapeutic Strategies
Iqbal, A.; Ali, F.; Aziz, M.; Shakil, A. U.; Choudhary, S.; Qayyum, A.; Arshad, F.; Ashraf, S.; Sehgal, S. A.; Hussain, M.; Sajid, M.
10.1101/2023.09.09.556929 — bioinformatics — Posted on 2023-09-12
3153 The rural urban divide, insights from immuno-genetic profiles and implications for health
Hamad, R.; Eid, N. A.; Saeed, A.; Abuswar, S. A. E.; Hussain, A.; Rockett, K.; Kwiatkowski, D.; Ibrahim, M.; Elhassan, I.; Elhassan, A.
10.1101/2023.09.08.556879 — immunology — Posted on 2023-09-12
3156 Longevity interventions in Titan mice attenuate frailty and senescence accumulation
Gille, B.; Muller-Eigner, A.; Gottschalk, S.; Wytrwat, E.; Langhammer, M.; Peleg, S.
10.1101/2023.09.08.556694 — systems biology — Posted on 2023-09-12
3157 Escalating High-dimensional Imaging using Combinatorial Channel Multiplexing and Deep Learning
Ben-Uri, R.; Ben Shabat, L.; Bar-Tal, O.; Bussi, Y.; Maimon, N.; Keidar Haran, T.; Milo, I.; Elhanani, O.; Rochwarger, A.; Schürch, C. M.; Bagon, S.; Keren, L.
10.1101/2023.09.09.556962 — systems biology — Posted on 2023-09-12
3158 Dissecting Metabolic Landscape of Alveolar Macrophage
Malla, S.; Sajeevan, K. A.; Acharya, B.; Chowdhury, R.; Saha, R.
10.1101/2023.09.08.556783 — systems biology — Posted on 2023-09-12
3168 Simplicity: web-based visualization and analysis of high-throughput cancer cell line screens
Ling, A. L.; Zhang, W.; Lee, A. M.; Xia, Y.; Su, M.-C.; Gruener, R. F.; Jena, S.; Huang, Y.; Pareek, S.; Shan, Y.; Huang, R. S.
10.1101/2023.09.08.556619 — pharmacology and toxicology — Posted on 2023-09-12
3170 The effects of CYP2C19 metaboliser status on DNA methylation
Shen, C.; Adams, M. J.; Davyson, E.; Iveson, M.; McIntosh, A. M.; Shen, X.
10.1101/2023.09.07.555071 — pharmacology and toxicology — Posted on 2023-09-12
3171 The Effect of Amniotic Fluid On Haıir Follicle Growth
Tumentemur, G.; Aygun, E. G.; Yurtsever, B.; Cakirsoy, D.; Ovali, E.
10.1101/2023.09.08.556806 — pathology — Posted on 2023-09-12
3172 Spatial molecular profiling of mixed invasive ductal-lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures and actionable driver mutations
Shah, O. S.; Nasrazadani, A.; Foldi, J.; Atkinson, J. M.; Kleer, C. G.; McAuliffe, P. F.; Da Silva, E. M.; Selenica, P.; Dopeso, H.; Pareja, F.; Mandelker, D.; Weigelt, B.; Reis-Filho, J. S.; Bhargava, R.; Lucas, P. C.; Lee, A. V.; Oesterreich, S.
10.1101/2023.09.09.557013 — cancer biology — Posted on 2023-09-12
3175 The Immune-Evasive Proline 283 Substitution in Influenza Nucleoprotein Increases Aggregation Propensity Without Altering the Native Structure
Yoon, J.; Zhang, Y. M.; Her, C.; Grant, R. A.; Ponomarenko, A. M.; Ackermann, B. E.; Debelouchina, G.; Shoulders, M. D.
10.1101/2023.09.08.556894 — biophysics — Posted on 2023-09-12
3177 Automated Bioinformatics Analysis via AutoBA
Zhou, J.; Zhang, B.; Chen, X.; Li, H.; Xu, X.; Chen, S.; Gao, X.
10.1101/2023.09.08.556814 — bioinformatics — Posted on 2023-09-12
3178 CodonBERT: Large Language Models for mRNA Design and Optimization
Li, S.; Moayedpour, S.; Li, R.; Bailey, M.; Riahi, S.; Miladi, M.; Miner, J.; Zheng, D.; Wang, J.; Balsubramani, A.; Tran, K.; Zacharia, M.; Wu, M.; Gu, X.; Clinton, R.; Asquith, C.; Skalesk, J.; Boeglin, L.; Chivukula, S.; Dias, A.; Montoya, F. U.; Agarwal, V.; Bar-Joseph, Z.; Dr. Jager, S.
10.1101/2023.09.09.556981 — bioinformatics — Posted on 2023-09-12
3183 Examining DNA Breathing with pyDNA-EPBD
Kabir, A.; Bhattarai, M.; Rasmussen, K. O.; Shehu, A.; Usheva, A.; Bishop, A. R.; Alexandrov, B. S.
10.1101/2023.09.09.557010 — genomics — Posted on 2023-09-12
3184 Effect of Sargassum on the Behavior and Survival of the Earthworm Eisenia fetida
Martinez-Cano, M.; Dorantes-Acosta, A. E.; Lara-Gonzalez, R.; Salgado-Hernandez, E.; Ortiz-Ceballos, A. I.
10.1101/2023.09.08.556937 — ecology — Posted on 2023-09-12
3185 Bet hedging in a unicellular microalga
Tang, S.; Liu, Y.; Hammerschmidt, K.; Zhu, J.; Cheng, X.; Liu, L.; Zhou, J.; Cai, Z.
10.1101/2023.09.08.556835 — ecology — Posted on 2023-09-12
3186 Phylogenetic diversity and regionalization of root nodule symbiosis
Folk, R. A.; Belitz, M.; Siniscalchi, C.; Kates, H. R.; Soltis, D. E.; Soltis, P. S.; Guralnick, R. P.; Borges, L. M.
10.1101/2023.09.08.556918 — ecology — Posted on 2023-09-12
3187 Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Zhang, G.; Zhang, Y.; Young, R.; Garvanska, D.; Song, C.; Zhai, Y.; Wang, Y.; Jiang, H.; Fang, J.; Nilsson, J.; Alfieri, C.
10.1101/2023.07.26.550666 — cell biology — Posted on 2023-09-12
3188 SARS-CoV-2 Omicron infection augments the magnitude and durability of systemic and mucosal immunity in triple-dose CoronaVac recipients
Chen, Y.; Zhao, T.; Chen, L.; Jiang, G.; Geng, Y.; Li, W.; Yin, S.; Tong, X.; Tao, Y.; Ni, J.; Lu, Q.; Ning, M.; Wu, C.
10.1101/2023.09.08.556870 — immunology — Posted on 2023-09-12
3189 Genetic Variants That Modify the Neuroendocrine Regulation of Foraging Behavior in C. elegans
Lee, H.; Boor, S. A.; Hilbert, Z. A.; Meisel, J. D.; Park, J.; Wang, Y.; McKeown, R. J.; Fischer, S.; Andersen, E. C.; Kim, D. H.
10.1101/2023.09.09.556976 — neuroscience — Posted on 2023-09-12
3190 Human HPSE2 gene transfer ameliorates bladder pathophysiology in a mutant mouse model of urofacial syndrome.
Lopes, F. M.; Grenier, C.; Jarvis, B. W.; Al Mahdy, S.; Lene-Mckay, A.; Gurney, A. M.; Newman, W. G.; Waddington, S. N.; Woolf, A. S.; Roberts, N. A.
10.1101/2023.07.03.547034 — neuroscience — Posted on 2023-09-12
3193 Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection
Loehr, A. R.; Timmerman, D. M.; Liu, M.; Gillis, A. J. M.; Matthews, M. D.; Bloom, J. C.; Nicholls, P. K.; Page, D. C.; Miller, A. D.; Looijenga, L. H. J.; Weiss, R. S.
10.1101/2023.09.09.556995 — cancer biology — Posted on 2023-09-12
3194 Thermodynamic Stabilization of Human Frataxin
Nunez-Franco, R.; Torres-Mozas, A.; Navo, C. D.; Schedlbauer, A.; Azkargorta, M.; Iloro, I.; Elortza, F.; Ortega, G.; Millet, O.; Peccati, F.; Jimenez-Oses, G.
10.1101/2023.09.08.556816 — biophysics — Posted on 2023-09-12
3196 Identification of cell types, states and programs by learning gene set representations
Hediyeh-zadeh, S.; Whitfield, H. J.; Kharbanda, M.; Curion, F.; Bhuva, D. D.; Theis, F. J.; Davis, M. J.
10.1101/2023.09.08.556842 — bioinformatics — Posted on 2023-09-12
3202 Caliban: Accurate cell tracking and lineage construction in live-cell imaging experiments with deep learning
Schwartz, M.; Moen, E.; Miller, G.; Dougherty, T.; Borba, E.; Ding, R.; Graf, W.; Pao, E.; Van Valen, D. A.
10.1101/803205 — bioinformatics — Posted on 2023-09-12
3203 DelSIEVE: joint inference of single-nucleotide variants, somatic deletions, and cell phylogeny from single-cell DNA sequencing data
Kang, S.; Borgsmüller, N.; Valecha, M.; Markowska, M.; Kuipers, J.; Beerenwinkel, N.; Posada, D.; Szczurek, E.
10.1101/2023.09.09.556903 — bioinformatics — Posted on 2023-09-12
3204 Modeling Cystic Fibrosis Chronic Infection Using Engineered Mucus-like Hydrogels
O'Brien, C.; Spencer, S. M.; Jafari, N.; Huang, A.; Scott, A.; Cheng, Z.; Leung, B. M.
10.1101/2023.09.07.556675 — bioengineering — Posted on 2023-09-12
3207 Next-generation sequencing-based liquid biopsy can be used for detection of residual disease and cancer recurrence monitoring in dogs
McCleary-Wheeler, A. L.; Fiaux, P. C.; Ruiz-Perez, C. A.; McLennan, L. M.; Tynan, J. A.; Hicks, S. C.; Rafalko, J. M.; Grosu, D. S.; Chibuk, J.; O'Kell, A. L.; Cohen, T. A.; Flesner, B. K.; Chorny, I.; Tsui, D. W.; Kruglyak, K. M.; Flory, A.
10.1101/2023.09.08.556935 — genomics — Posted on 2023-09-12
3208 High throughput evaluation of genetic variants with prime editing sensor libraries
Gould, S. I.; Wuest, A. N.; Dong, K.; Johnson, G. A.; Hsu, A.; Narendra, V. K.; Levine, S. S.; Liu, D. R.; Sanchez-Rivera, F. J.
10.1101/2022.10.26.513842 — genetics — Posted on 2023-09-12
3213 Household geckos as a potential vector for Salmonella transmission in Malawi
Wilson, C. N.; Musicha, P.; Beale, M. A.; Diness, Y.; Kanjerwa, O.; Salifu, C.; Katuah, Z. J.; Duncan, P.; Nyangu, J.; Mungu, A.; Deleza, M.; Banda, L.; Elviss, N.; Jewell, C.; Pinchbeck, G.; Thomson, N.; Feasey, N. A.; Fevre, E. M.
10.1101/2023.09.08.556805 — ecology — Posted on 2023-09-12
3214 Scale-dependent landscape-biodiversity relationships shape multi-taxa diversity in an oil palm monoculture under restoration
Cayetano, D. T.; Zemp, D. C.; Buchori, D.; Fiedler, S.; Grass, I.; Hölscher, D.; Irawan, B.; Korol, Y.; Khokthong, W.; Paterno, G. B.; Polle, A.; Potapov, A.; Sundawati, L.; Tscharntke, T.; Westphal, C.; Weigelt, P.; Wiegand, K.; Kreft, H.; Guerrero-Ramirez, N. R.
10.1101/2023.09.08.556058 — ecology — Posted on 2023-09-12
3216 Lupus IgA1 autoantibodies synergize with IgG to enhance plasmacytoid dendritic cell responses to RNA-containing immune complexes
Waterman, H. R.; Dufort, M. J.; Posso, S. E.; Ni, M.; Li, L. Z.; Zhu, C.; Raj, P.; Buckner, J. H.; Hamerman, J. A.
10.1101/2023.09.07.556743 — immunology — Posted on 2023-09-12
3217 A high-resolution map of functional miR-181 response elements in the thymus reveals the role of coding sequence targeting and an alternative seed match
Verheyden, N. A.; Klostermann, M.; Bruggemann, M.; Scholz, A.; Amr, S.; Lichtenthaeler, C.; Munch, C.; Schmid, T.; Zarnack, K.; Krueger, A.
10.1101/2023.09.08.556730 — immunology — Posted on 2023-09-12
3223 Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state
Paryani, F.; Kwon, J.-S.; Ng, C. W.; Madden, N.; Ofori, K.; Tang, A.; Lu, H.; Li, J.; Mahajan, A.; Davidson, S. M.; Basile, A.; McHugh, C.; Vonsattel, J. P.; Hickman, R.; Zody, M.; Houseman, D. E.; Goldman, J. E.; Yoo, A. E.; Menon, V.; Al-Dalahmah, O.
10.1101/2023.09.08.556867 — neuroscience — Posted on 2023-09-12
3226 The effect of lactational low protein diet on skeletal muscle during adulthood and ageing in male and female mouse offspring
Alameddine, M.; Altinpinar, A. E.; Ersoy, U.; Kanakis, I.; Myrtziou-Kanaki, I.; E. Ozanne, S.; Goljanek-Whysall, K.; Vasilaki, A.
10.1101/2023.09.07.556663 — physiology — Posted on 2023-09-12
3227 Beyond Myosin Heavy Chains: Ribosomal Specialization Drives Human Skeletal Muscle Fiber Heterogeneity
Moreno-Justicia, R.; Van der Stede, T.; Stocks, B.; Laitila, J.; Seaborne, R. A.; Van de Loock, A.; Lievens, E.; Marin-Arraiza, L.; Van Vossel, K.; Yigit, N.; Anckaert, J.; Weyns, A.; Van Thienen, R.; Sahl, R. E.; Zanoteli, E.; Lawlor, M. W.; Mestdagh, P.; Vandesompele, J.; Ochala, J.; Hostrup, M.; Derave, W.; Deshmukh, A. S.
10.1101/2023.09.07.556665 — physiology — Posted on 2023-09-12
3231 Local read haplotagging enables accurate long-read small variant calling
Kolesnikov, A.; Cook, D. E.; Nattestad, M.; Ashley, E. A.; Gorzynski, J.; Goenka, S. D.; Jain, M.; McNulty, B.; Miga, K. H.; Paten, B.; Chang, P.-C.; Carroll, A.; Shafin, K.
10.1101/2023.09.07.556731 — bioinformatics — Posted on 2023-09-12
3232 eMIND: Enabling automatic collection of protein variation impacts in Alzheimer's disease from the literature
Gupta, S.; Qin, X.; Wang, Q.; Cowart, J.; Huang, H.; Wu, C. H.; Vijay-Shanker, K.; Arighi, C. N.
10.1101/2023.09.07.556602 — bioinformatics — Posted on 2023-09-12
3233 Prediction of mycotoxin response of DNA-wrapped nanotube sensor with machine learning
Rabbani, Y.; Behjat, S.; Lambert, B.; Sajjadi, S. H.; Shariaty-Niassar, M.; Boghossian, A.
10.1101/2023.09.07.556334 — bioengineering — Posted on 2023-09-12
3234 Spatiospectral image processing workflow considerations for advanced MR spectroscopy of the brain
Cai, L. Y.; Del Tufo, S. N.; Barquero, L.; D'Archangel, M.; Sachs, L.; Cutting, L.; Glaser, N.; Ghetti, S.; Jaser, S. S.; Anderson, A. W.; Jordan, L. C.; Landman, B. A.
10.1101/2023.09.07.556701 — bioengineering — Posted on 2023-09-12
3238 Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor
Palikyras, S.; Sofiadis, K.; Stavropoulou, A.; Danieli-Mackay, A.; Varamogianni-Mamatsi, V.; Hoerl, D.; Nasiscionyte, S.; Zhu, Y.; Josipovic, N.; Papadakis, A.; Zirkel, A.; O'Connell, A.; Loughran, G.; Keane, J.; Michel, A.; Wagner, W.; Beyer, A.; Harz, H.; Leonhardt, H.; Lukinavicius, G.; Nikolaou, C.; Papantonis, A.
10.1101/2023.09.07.556710 — genomics — Posted on 2023-09-12
3240 Disentangling sources of clock-like mutations in germline and soma
Spisak, N.; de Manuel, M.; Milligan, W. R.; Sella, G.; Przeworski, M.
10.1101/2023.09.07.556720 — genetics — Posted on 2023-09-12
3242 Forest cover is more important than habitat integrity or landscape configuration in determining habitat use by mammals in a human-modified landscape in Colombia
Pardo, L. E.; Gomez-Valencia, B.; Deere, N.; Herrera Varon, Y.; Soto, C.; Noguera-Urbano, E. A.; Sanchez-Clavijo, L. M.; Romero, L.; Diaz-Pulido, A.; Ochoa-Quintero, J. M.
10.1101/2023.02.27.530271 — ecology — Posted on 2023-09-12
3243 Combining environmental DNA and remote sensing for efficient, fine-scale mapping of arthropod biodiversity
Li, Y.; Devenish, C.; Tosa, M.; Luo, M.; Bell, D.; Lesmeister, D.; Greenfield, P.; Pichler, M.; Levi, T.; Yu, D. W.
10.1101/2023.09.07.556488 — ecology — Posted on 2023-09-12
3244 Disrupting traditions of science: Indigenous Knowledge to model species habitat use
Gryba, R.; Von Duyke, A.; Huntington, H.; Adams, B.; Frantz, B.; Gatten, J.; Harcharek, Q.; Sarren, R.; Henry, G.; Auger-Methe, M.
10.1101/2023.09.07.556613 — ecology — Posted on 2023-09-12
3247 VLP-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice
Barajas, A.; Amengual-Rigo, P.; Pons-Grifols, A.; Ortiz, R.; Garcia Carmona, O.; Urrea, V.; de la Iglesia, N.; Blanco-Heredia, J.; Anjos-Souza, C.; Varela, I.; Trinite, B.; Tarres-Freixas, F.; Rovirosa, C.; Lepore, R.; Vazquez, M.; de Mattos-Arruda, L.; Valencia, A.; Clotet, B.; Aguilar-Gurrieri, C.; Guallar, V.; Carrillo, J.; Blanco, J.
10.1101/2023.09.07.556652 — immunology — Posted on 2023-09-12
3248 Postnatal intestinal epithelial maturation by LSD1 controls the small intestinal immune cell composition independently from the microbiota
Diez-Sanchez, A.; Lindholm, H. T.; Vornewald, P. M.; Ostrop, J.; Parmar, N.; Shaw, T. N.; Martin-Alonso, M.; Oudhoff, M. J.
10.1101/2023.09.08.556818 — immunology — Posted on 2023-09-12
3249 Single neurons in thalamus and subthalamic nucleus process cardiac and respiratory signals in humans
De Falco, E.; Solca, M.; Bernasconi, F.; Babo-Rebelo, M.; Young, N.; Sammartino, F.; Rezai, A.; Krishna, V.; Blanke, O.
10.1101/2022.07.25.501133 — neuroscience — Posted on 2023-09-12
3251 Auxin Exposure Disrupts Feeding Behavior and Fatty Acid Metabolism in Adult Drosophila
Fleck, S. A.; Biswas, P.; DeWitt, E. D.; Knuteson, R. L.; Eisman, R. C.; Nemkov, T.; D'Alessandro, A.; Tennessen, J. M.; Rideout, E. J.; Weaver, L. N.
10.1101/2023.08.15.553385 — physiology — Posted on 2023-09-12
3252 Chronic high-sugar diet in adulthood protects Caenorhabditis elegans from 6-OHDA induced dopaminergic neurodegeneration
Morton, K. S.; Hartman, J. S.; Heffernan, N.; Ryde, I.; Kenny-Ganzert, I. W.; Meng, L.; Sherwood, D. R.; Meyer, J. N.
10.1101/2023.05.29.542737 — pharmacology and toxicology — Posted on 2023-09-12
3253 Axial de-scanning using remote focusing in the detection arm of light-sheet microscopy
Dibaji, H.; Shotorban, A. K. N.; Habibi, M.; Grattan, R. M.; Lucero, S.; Schodt, D. J.; Lidke, K. A.; Petruccelli, J.; Lidke, D. S.; Liu, S.; Chakraborty, T.
10.1101/2023.09.07.556729 — biophysics — Posted on 2023-09-12
3257 The autism-associated gene SYNGAP1 regulates human cortical neurogenesis
Birtele, M.; Del Dosso, A.; Xu, T.; Nguyen, T.; Wilkinson, B.; Hosseini, N. H.; Nguyen, S.; Urenda, J.-P.; Knight, G.; Rojas, C.; Flores, I.; Atamian, A.; Moore, R.; Sharma, R.; Pirrotte, P.; Ashton, R. S.; Huang, E. J.; Rumbaugh, G.; Coba, M. P.; Quadrato, G.
10.1101/2022.05.10.491244 — developmental biology — Posted on 2023-09-12
3259 A biobank-scale test of marginal epistasis reveals genome-wide signals of polygenic epistasis
Fu, B.; Pazokitoroudi, A.; Xue, A.; Anand, A.; Anand, P.; Zaitlen, N.; Sankararaman, S.
10.1101/2023.09.10.557084 — genetics — Posted on 2023-09-12
3261 Targeting monocytic Occludin impairs monocyte transmigration and HIV neuroinvasion
Brychka, D.; Ayala-Nunez, N. V.; Bare, Y.; Dupas, A.; Partiot, E.; Mittelheisser, V.; Lucansky, V.; Goetz, J. G.; Osmani, N.; Gaudin, R.
10.1101/2023.09.11.557242 — cell biology — Posted on 2023-09-12
3262 Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation
Shinoda, S.; Sakai, Y.; Matsui, T.; Uematsu, M.; Koyama-Honda, I.; Sakamaki, J.-i.; Yamamoto, H.; Mizushima, N.
10.1101/2023.09.11.557142 — cell biology — Posted on 2023-09-12
3264 The Bicaudal-D/Egalitarian complex defines the specificity of cargo transport by Dynein.
Baker, F. C.; Lu, W.; Lakonishok, M.; Neiswender, H.; Veeranan-Karmegam, R.; Allen, P.; Badieyan, S.; Cianfrocco, M. A.; Gelfand, V.; Gonsalvez, G. B.
10.1101/2023.09.11.557182 — cell biology — Posted on 2023-09-12
3265 Parkinson's genes orchestrate pyroptosis through selective trafficking of mtDNA to leaky lysosomes
Nguyen, M.; Collier, J. J.; Ignatenko, O.; Morin, G.; Huang, S.; Desjardins, M.; McBride, H. M.
10.1101/2023.09.11.557213 — cell biology — Posted on 2023-09-12
3266 Rab35 is required for embryonic development and kidney and ureter homeostasis through regulation of epithelial cell junctions
Clearman, K. R.; Timpratoom, N.; Patel, D.; Rains, A. B.; Haycraft, C. J. R.; Croyle, M. J.; Reiter, J. F.; Yoder, B. K.
10.1101/2023.09.11.556924 — cell biology — Posted on 2023-09-12
3267 Clustering of cortical dynein regulates the mechanics of spindle orientation in human mitotic cells
Anjur-Dietrich, M.; Hererra, V. G.; Farhadifar, R.; Wu, H.-Y.; Merta, H.; Bahmanyar, S.; Shelley, M.; Needleman, D.
10.1101/2023.09.11.557210 — cell biology — Posted on 2023-09-12
3268 miRNA and mRNA Signatures in Human Acute Kidney Injury Tissue
Janosevic, D.; De Luca, T.; Ferreira, R. M.; Gisch, D. L.; Hato, T.; Luo, J.; Yang, Y.; Hodgin, J. B.; Dagher, P. C.; Eadon, M. T.
10.1101/2023.09.11.557054 — cell biology — Posted on 2023-09-12
3270 In Vivo Structural Connectivity of the Reward System Along the Hippocampal Long-Axis
Elliott, B. L.; Mohyee, R. A.; Ballard, I. C.; Olson, I. R.; Ellman, L. M.; Murty, V. P.
10.1101/2023.09.11.556537 — neuroscience — Posted on 2023-09-12
3271 Of mice and men: Increased dendritic complexity gives rise to unique human networks
Kanari, L.; Shi, Y.; Arnaudon, A.; Barros Zulaica, N.; Benavides-Piccione, R.; Coggan, J. S.; DeFelipe, J. D.; Hess, K.; Mansvelder, H.; Mertens, E. J.; Segev, I.; Markram, H.; de Kock, C. P.
10.1101/2023.09.11.557170 — neuroscience — Posted on 2023-09-12
3272 Instinct to insight: Neural correlates of ethological strategy learning
Lu, K.; Wong, K. T.; Zhou, L. N.; Shi, Y. T.; Yang, C. J.; Liu, R. C.
10.1101/2023.09.11.557240 — neuroscience — Posted on 2023-09-12
3274 Modularity of biological systems: a link between structure and function
Kadelka, C.; Wheeler, M.; Veliz-Cuba, A.; Murrugarra, D.; Laubenbacher, R.
10.1101/2023.09.11.557227 — systems biology — Posted on 2023-09-12
3275 Improved Super-Resolution Ribosome Profiling Revealed Prevalent Translation of Upstream ORFs and Small ORFs in Arabidopsis
Wu, L.; Ai, Q.; Teixeira, R. T.; Song, G.; Montes-Serey, C.; Elmore, J. M.; Walley, J.; Hsu, P. Y.
10.1101/2023.09.08.556947 — genomics — Posted on 2023-09-11
3276 Anemonefish are better taxonomists than humans.
Kashimoto, R.; Mercader, M.; Zwahlen, J.; Miura, S.; Tanimoto, M.; Yanagi, K.; Reimer, J. D.; Khalturin, K.; Laudet, V.
10.1101/2023.09.11.557259 — evolutionary biology — Posted on 2023-09-11
3277 NRF2 pathway activation reverts high-glucose-induced transcriptional memory in endothelial cells
Wilson-Verdugo, M.; Bustos-Garcia, B.; Adame-Guerrero, O.; Hersch-Gonzalez, J.; Cano-Dominguez, N.; Soto-Nava, M.; Acosta, C.; Tusie-Luna, T.; Avila-Rios, S.; Noriega, L. G.; Valdes, V. J.
10.1101/2023.09.11.557207 — molecular biology — Posted on 2023-09-11
3279 ALS-associated FUS mutation reshapes the RNA and protein composition and dynamic of Stress Granules.
Mariani, D.; Setti, A.; Castagnetti, F.; Vitiello, E.; Mecarelli, L. S.; Di Timoteo, G.; Giuliani, A.; Perego, E.; Zappone, S.; Vicidomini, G.; Liessi, N.; Armirotti, A.; Bozzoni, I.
10.1101/2023.09.11.557245 — molecular biology — Posted on 2023-09-11
3281 NF2 Loss-of-Function and Hypoxia Drive Radiation Resistance in Grade 2 Meningiomas
Patel, B.; Pugazenthi, S.; English, C. W.; Mahlokozera, T.; Leidig, W. A.; Lu, H.-C.; Yang, A.; Roberts, K.; DeSouza, P.; Mao, D. D.; Sinha, N.; Ippolito, J. E.; Dahiya, S.; Petti, A. A.; Yano, H.; Klisch, T. J.; Harmanci, A. S.; Patel, A. J.; Kim, A. H.
10.1101/2023.09.08.556892 — molecular biology — Posted on 2023-09-11
3285 Streptococcus pneumoniae serotype 33G: genetic, serological, and structural analysis of a new capsule type
Manna, S.; Werren, J. P.; Ortika, B. D.; Bellich, B.; Pell, C. L.; Nikolaou, E.; Gjuroski, I.; Lo, S. W.; Hinds, J.; Tundev, O.; Dunne, E. M.; Gessner, B. D.; Bentley, S. D.; Russell, F.; Mulholland, E. K.; Mungun, T.; von Mollendorf, C.; Licciardi, P. V.; Cescutti, P.; Ravenscroft, N.; Hilty, M.; Satzke, C.
10.1101/2023.09.11.556596 — microbiology — Posted on 2023-09-11
3287 Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2
Liang, S.; Liu, A.; Liu, Y.; Wang, F.; Zhou, Y.; Wang, T.; Liu, Z.; Ren, R.; Ye, R. D.
10.1101/2023.09.11.557130 — immunology — Posted on 2023-09-11
3288 VAMP2/Munc18-1 domain 3a interaction controls the nanoscale reorganization underpinning vesicular priming
Meunier, F. A.; Jiang, A.; Gormal, R. S.; Kasula, R.; Blum, A.; Salla-Martret, M.; Chai, Y. J.; Wallis, T. P.; Brouillet, J. Z.; Padmanabhan, P.; Weeratunga, S.; Livingstone, E.; Mollazade, M.; Joensuu, M.; Martinez-Marmol, R.; Collins, B.
10.1101/2023.09.10.556776 — neuroscience — Posted on 2023-09-11
3289 Engineering synthetic phosphorylation signaling networks in human cells
Yang, X.; Rocks, J. W.; Jiang, K.; Walters, A. J.; Rai, K.; Liu, J.; Nguyen, J.; Olson, S. D.; Mehta, P.; Collins, J. J.; Daringer, N. M.; Bashor, C. J.
10.1101/2023.09.11.557100 — synthetic biology — Posted on 2023-09-11
3291 Modeling flexible protein structure with AlphaFold2 and cross-linking mass spectrometry
Manalastas-Cantos, K.; Adoni, K. R.; Pfeifer, M.; Maertens, B.; Grunewald, K.; Thalassinos, K.; Topf, M.
10.1101/2023.09.11.557128 — biochemistry — Posted on 2023-09-11
3292 Droplet based low input proteomic platform for rare cell populations
Waas, M.; Khoo, A.; Tharmapalan, P.; McCloskey, C. W.; Govindarajan, M.; Zhang, B.; Khan, S.; Waterhouse, P.; Khokha, R.; Kislinger, T.
10.1101/2023.09.11.557098 — biochemistry — Posted on 2023-09-11
3293 Biological and Genetic Determinants of Red Blood Cell Glycolysis
Nemkov, T.; Stephenson, D.; Earley, E. J.; Keele, G. R.; Hay, A.; Erickson, C.; Dzieciatkowska, M.; Key, A. M.; Moore, A.; Stone, M.; Deng, X.; Kleinman, S.; Spitalnik, S. L.; Hod, E. A.; Hansen, K.; Churchill, G. A.; Roubinian, N.; Norris, P. J.; Busch, M. P.; Zimring, J. C.; Page, G. P.; D'Alessandro, A.
10.1101/2023.09.11.557250 — biochemistry — Posted on 2023-09-11
3295 Influenza A virus activates the unfolded protein response and induces the accumulation of insoluble protein aggregates that are essential for efficient viral propagation
Marques, M.; Ramos, B.; Albuquerque, H.; Pereira, M.; Ribeiro, D. R.; Nunes, A.; Sarabando, J.; Bras, D.; Ferreira, A. R.; Vitorino, R.; Amorim, M. J.; Silva, A.; Soares, A. R.; Ribeiro, D.
10.1101/2023.09.11.557148 — microbiology — Posted on 2023-09-11
3297 Suppression of progesterone by influenza A virus causes adverse maternal and fetal outcomes in mice
Creisher, P. S.; Parish, M. A.; Lei, J.; Liu, J.; Perry, J. L.; Campbell, A. D.; Sherer, M. L.; Burd, I.; Klein, S. L. L.
10.1101/2023.09.11.557146 — microbiology — Posted on 2023-09-11
3300 Plasmodium falciparum MORC protein modulates gene expression through interaction with heterochromatin
Singh, M. K.; Bonnell, V.; Silva, I.; Santiago, V. F.; Moraes, M.; Adderley, J.; Doerig, C.; Palmisano, G.; Llinas, M.; Garcia, C. R.
10.1101/2023.09.11.557196 — microbiology — Posted on 2023-09-11
3302 PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, P. falciparum.
Chahine, Z. M.; Gupta, M.; Lenz, T.; Hollin, T.; Abel, S.; Banks, C.; Saraf, A.; Prudhomme, J.; Florens, L.; Le Roch, K. G.
10.1101/2023.09.11.557253 — microbiology — Posted on 2023-09-11
3306 Untargeted Metabolomics to Expand the Chemical Space of the Marine Diatom Skeletonema marinoi
Zulfiqar, M.; Stettin, D.; Schmidt, S.; Nikitashina, V.; Pohnert, G.; Steinbeck, C.; Peters, K.; Sorokina, M.
10.1101/2023.09.07.556696 — microbiology — Posted on 2023-09-11
3307 Less neutralization evasion of SARS-CoV-2 BA.2.86 than XBB sublineages and CH.1.1
Hu, Y.; Zou, J.; Kurhade, C.; Deng, X.; Chang, H. C.; Kim, D. K.; Shi, P.-Y.; Ren, P.; Xie, X.
10.1101/2023.09.10.557047 — microbiology — Posted on 2023-09-11
3308 Contrasting Effects of SARS-CoV-2 Vaccination vs. Infection on Antibody and TCR Repertoires
Braun, J.; Hill, E. D.; Contreras, E.; Yasuda, M.; Morgan, A.; Ditelberg, S.; Winter, E.; Callahan, C.; Mazzoni, G.; Kirmaier, A.; Mirebrahim, H.; Asgharian, H.; Telman, D.; Collier, A.-R. Y.; Barouch, D. H.; Riedel, S.; Dutta, S.; Rubelt, F.; Arnaout, R.
10.1101/2023.09.08.556703 — immunology — Posted on 2023-09-11
3309 Enhanced Omicron subvariant cross-neutralization efficacy of a monovalent SARS-CoV-2 BA.4/5 mRNA vaccine encoding a noncleaved, nonfusogenic spike antigen
Seo, H. Y.; Jung, H.; Woo, H.; Jung, H.-G.; Bak, Y.; Lee, S.-Y.; Son, Y.-M.; Yoon, G.; Son, Y.-M.; Hwang, S.-Y.; Park, I.; Shin, J.-S.; Oh, J.-W.
10.1101/2023.09.10.557088 — immunology — Posted on 2023-09-11
3310 Protocol for primary human lung organoid-derived air-liquid interface in vitro model to study response to SARS-CoV-2
Castaneda, D. C.; Jangra, S.; Yurieva, M.; Martinek, J.; Callender, M.; Coxe, M.; Choi, A.; Diego, J. G.-B.; Wu, T.-C.; Marches, F.; Chaussabel, D.; Garcia-Sastre, A.; Schotsaert, M.; Williams, A.; Palucka, K.
10.1101/2023.09.10.557067 — immunology — Posted on 2023-09-11
3311 Production results indicate that parvovirus IHHNV should be delisted as a notifiable shrimp disease
Sritunyalucksana, K.; Sanguanrut, P.; Srisala, J.; Thawonsuwan, J.; Saleetid, N.; Vanichviriyakit, R.; Chotwiwatthanakun, C.; FLEGEL, T. W.; Taengchaiyaphum, S.
10.1101/2023.09.08.556791 — zoology — Posted on 2023-09-11
3312 Bayesian phylogenetics on globally emerging SARS-CoV-2 variant BA.2.86 suggest global distribution and rapid evolution
Rothstein, A. P.; Qiu, X.; Robison, K.; Collins, S.; Muir, G.; Lu, B.; Plocik, A.; Simen, B.; Philipson, C.
10.1101/2023.09.08.556912 — bioinformatics — Posted on 2023-09-11
3314 The role of ion dissolution in metal and metal oxide surface inactivation of SARS-CoV-2
Hilton, J.; Nanao, Y.; Flokstra, M.; Askari, M.; Smith, T. K.; Di Falco, A.; King, P. D.; Wahl, P.; Adamson, C. S.
10.1101/2023.09.08.556901 — microbiology — Posted on 2023-09-11
3316 Characterization of SARS-CoV-2 Convalescent Patients' Serological Repertoire Reveals High Prevalence of Iso-RBD Antibodies
Curtis, N. C.; Shin, S.; Hederman, A. P.; Connor, R. I.; Wieland-Alter, W. F.; Ionov, S.; Boylston, J.; Rose, J.; Sakharkar, M.; Dorman, D. B.; Dessaint, J. A.; Gwilt, L. L.; Crowley, A. R.; Feldman, J.; Hauser, B. M.; Schmidt, A. G.; Ashare, A.; Walker, L. M.; Wright, P. F.; Ackerman, M. E.; Lee, J.
10.1101/2023.09.08.556349 — immunology — Posted on 2023-09-11
3318 Gcoupler: An AI-enhanced tool unveiled Endogenous Intracellular Allosteric Modulators of Evolutionary Conserved GPCR-Gα Interface
Mohanty, S. K.; Mittal, A.; Gaur, A.; Solanki, S.; Duari, S.; Arora, S.; Kumar, S.; Gautam, V.; Dixit, N. K.; Subramanian, K.; Ghosh, T. S.; Sengupta, D.; Gupta, S. K.; Murugan, N. A.; Ahuja, G.
10.1101/2023.02.14.528587 — bioinformatics — Posted on 2023-09-11
3319 A Clear, Legible, Explainable, Transparent, and Elucidative (CLETE) Binary Classification Platform for Tabular Data
Nasimian, A.; Younus, S.; Tatli, O.; Hammarlund, E. U.; Pienta, K. J.; Rönnstrand, L.; Kazi, J. U.
10.1101/2023.06.20.545752 — bioinformatics — Posted on 2023-09-11
3320 How useful is genomic data for predicting maladaptation to future climate?
Lind, B. M.; Candido-Ribeiro, R.; Singh, P.; Lu, M.; Obreht Vidakovic, D.; Booker, T. R.; Whitlock, M. C.; Yeaman, S.; Isabel, N.; Aitken, S. N.
10.1101/2023.02.10.528022 — evolutionary biology — Posted on 2023-09-11
3322 Targeting BMI-1 to deplete antibody-secreting cells in autoimmunity
Polmear, J.; Hailes, L.; Olshansky, M.; Rischmueller, M.; L'Estrange-Stranieri, E.; Fletcher, A.; Hibbs, M.; Bryant, V.; Good-Jacobson, K.
10.1101/2023.07.27.550912 — immunology — Posted on 2023-09-11
3323 Pathogenic soluble tau peptide disrupts endothelial calcium signaling and vasodilation in the brain microvasculature
Freeman, K.; Sackheim, A.; Mughal, A.; Koide, M.; Bonson, G.; Ebner, G.; Hennig, G.; Lockette, W.; Nelson, M. T.
10.1101/2023.08.08.552492 — neuroscience — Posted on 2023-09-11
3326 Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics
Khanppnavar, B.; Schuster, D.; Lavriha, P.; Uliana, F.; Özel, M.; Mehta, V.; Leitner, A.; Picotti, P.; Korkhov, V. M.
10.1101/2023.03.03.531047 — biochemistry — Posted on 2023-09-11
3330 Whole Genome Sequencing based Identification of Human Tuberculosis caused by Animal-lineage Mycobacterium orygis
Islam, M. R.; Sharma, M. K.; KhunKhun, R.; Shandro, C.; Sekirov, I.; Tyrrell, G. J.; Soualhine, H.
10.1101/2023.02.27.530375 — microbiology — Posted on 2023-09-11
3331 Mouthparts of the bumblebee (Bombus terrestris) exhibit poor acuity for the detection of pesticides in nectar
Parkinson, R. H.; Scott, J.; Jones, H.; Dorling, A. L.; McDermott-Roberts, A. E.; Haslam, M.; Wright, G. A.
10.1101/2023.02.03.526956 — neuroscience — Posted on 2023-09-11
3334 Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase
Colin, L.; Reyes, C.; Berthezene, J.; Maestroni, L.; Modolo, L.; Toselli, E.; Chanard, N.; Schaak, S.; Cuvier, O.; Gachet, Y.; Coulon, S.; Bernard, P.; Tournier, S.
10.1101/2022.03.18.484892 — cell biology — Posted on 2023-09-11
3335 WITHDRAWN: In vivo CRISPR screen defines Slc25a37 as an organ-specific regulator of antioxidant metabolism in metastasis
Cuadros, A. M.; Fernandez-Garcia, J.; Planque, M.; Altea-Manzano, P.; Schalley, T.; Vermeire, I.; Broekaert, D.; Wu, Q.; Van Brussel, T.; Leduc, S.; Maetens, M.; Nguyen, H.-L.; Van Baelen, K.; Darzi, N.; Floris, G.; Wildiers, H.; Desmedt, C.; Lambrechts, D.; Fendt, S.-M.
10.1101/2022.09.03.506468 — cancer biology — Posted on 2023-09-11
3336 When cheating turns into a stabilizing mechanism of mutualistic networks
Duchenne, F.; Aubert, S.; Barreto, E.; Brenes, E.; Maglianesi, M. A.; Santander, T.; Guevara, E. A.; Graham, C. H.
10.1101/2023.03.31.533549 — ecology — Posted on 2023-09-11
3337 Exploring the principles of embryonic mammary gland branching morphogenesis
Lindstrom, R.; Satta, J. P.; Myllymaki, S.-M.; Lan, Q.; Trela, E.; Prunskaite-Hyyrylainen, R.; Kaczynska, B.; Voutilainen, M.; Kuure, S.; Vainio, S. J.; Mikkola, M. L.
10.1101/2022.08.23.504958 — developmental biology — Posted on 2023-09-11
3338 Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform
Kipfer, E. T.; Hauser, D.; Lett, M. J.; Otte, F.; Urda, L.; Zhang, Y.; Lang, C. M. R.; Chami, M.; Mittelholzer, C.; Klimkait, T.
10.1101/2023.05.11.540343 — molecular biology — Posted on 2023-09-11
3342 Control of cell fate specification and patterning by an ancestral microRNA
Aguilar-Cruz, A.; Flores-Sandoval, E.; Gutierrez-Ramos, X.; Oltehua-Lopez, O.; Dorantes-Acosta, A. E.; Trujillo, J. T.; Kato, H.; Ishizaki, K.; Mosher, R. A.; Dolan, L.; Grimanelli, D.; Haseloff, J.; Bowman, J. L.; Arteaga-Vazquez, M. A.
10.1101/2023.09.09.556951 — plant biology — Posted on 2023-09-11
3343 Genome size is positively correlated with extinction risk in herbaceous angiosperms
Gomez, M. S.; Brown, M. J.; Pironon, S.; Vesely, P.; Bures, P.; Elliott, T. L.; Zedek, F.; Pellicer, J.; Forest, F.; Lughadha, E. N.; Leitch, I. J.
10.1101/2023.09.10.557053 — plant biology — Posted on 2023-09-11
3344 Cellular gibberellin dynamics govern indeterminate nodule development, morphologyand function
Drapek, C.; Radzman-Mohd, N. A.; Rizza, A.; Schiessl, K.; Dos Santos Barbosa, F.; Wen, J.; Oldroyd, G. E. D.; Jones, A. M.
10.1101/2023.09.09.556959 — plant biology — Posted on 2023-09-11
3345 Natural variation in the zinc-finger-encoding exon of Prdm9 affects hybrid sterility phenotypes in mice
Abu Alia, K. F. N.; Damm, E.; Ullrich, K. K.; Mukaj, A.; Parvanov, E. D.; Forejt, J.; Odenthal-Hesse, L.
10.1101/2023.09.06.556583 — genetics — Posted on 2023-09-11
3346 Slave Trade and Colonial Expansion Resulted in Strong Sex-Biased Admixture in South Africa
Reynolds, A.; Schurz, H.; Meeks, G.; Gravel, S.; Myrick, J. W.; Mendez, F. L.; Werely, C.; van Helden, P. D.; Hoal, E. G.; Poznik, G. D.; Kim, M.; Uren, C.; Underhill, P. A.; Möller, M.; Henn, B. M.
10.1101/2023.09.06.556626 — genetics — Posted on 2023-09-11
3347 Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by single-cell transcriptomics
Qaqorh, T.; Takahashi, Y.; Otani, K.; Yazawa, I.; Nishida, Y.; Fujihara, Y.; Honda, M.; Oki, S.; Ohkawa, Y.; Thorburn, D. R.; Frazier, A. E.; Takeda, A.; Ikeda, Y.; Sakaguchi, H.; Watanabe, T.; Fukushima, N.; Tsukamoto, Y.; Makita, N.; Yamaguchi, O.; Murayama, K.; Otake, A.; Okazaki, Y.; Inoue, H.; Matsuoka, K.; Yamazaki, S.; Takashima, S.; Shintani, Y.
10.1101/2023.09.11.557118 — cell biology — Posted on 2023-09-11
3348 Key Proteins for Regeneration in A. mexicanum: Transcriptomic Insights from Aged and Juvenile Limbs
del Moral-Morales, A.; Samano, C.; Ocampo-Cervantes, J. A.; Topf, M.; Baumbach, J.; Gonzalez-Barrios, R.; Soto-Reyes, E.
10.1101/2023.09.07.556684 — molecular biology — Posted on 2023-09-11
3349 ZZZ3 protects human embryonic stem cells from nucleolar stress by boosting mTOR/ribosome pathway.
Lo Conte, M.; Lucchino, V.; Scalise, S.; Zannino, C.; Murfuni, M. S.; Cicconetti, C.; Scaramuzzino, L.; Matassa, D. S.; Procopio, A.; Cuda, G.; Parrotta, E. I.
10.1101/2023.09.08.556837 — molecular biology — Posted on 2023-09-11
3350 Merging Multi-OMICs with Proteome Integral Solubility Alteration Unveils Antibiotic Mode of Action
Sancho, J.; Maity, R.; Ainsa, J. A.; Gaetani, M.; Rinaldo, S.; Cutruzzola, F.; Liberati, F. R.; Zhang, X.
10.1101/2023.09.07.556692 — microbiology — Posted on 2023-09-11
3351 High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1
Bolland, W.; Michel, V.; Planas, D.; Hubert, M.; Guivel-Benhassine, F.; Porrot, F.; Staropoli, I.; N'Debi, M.; Rodriguez, C.; Fourati, S.; Prot, M.; Planchais, C.; Hocqueloux, L.; Simon-Loriere, E.; Mouquet, H.; Prazuck, T.; Pawlotsky, J.-M.; Bruel, T.; Schwartz, O.; Buchrieser, J.
10.1101/2023.09.06.556548 — microbiology — Posted on 2023-09-11
3352 Spatial and temporal control of lysis by the lambda holin
Cahill, J.; Holt, A.; Theodore, M.; Moreland, R.; O Leary, C.; Martin, C.; Bettridge, K.; Xiao, J.; Young, R.
10.1101/2023.09.08.556860 — microbiology — Posted on 2023-09-11
3353 A culture-based approach to study ecological interactions among the microbial species of the human scalp.
Bhattacharya, S.; Roth, T.; Costa, S.; Santoro, A.; Mazza, W.; Coyte, K.; Clavaud, C.; Foster, K.; Kim, W.
10.1101/2023.09.07.556667 — microbiology — Posted on 2023-09-11
3354 Large-scale phenotypic and genomic characterization of Listeria monocytogenes susceptibility to quaternary ammonium compounds
Ivanova, M.; Laage Kragh, M.; Szarvas, J.; Tosun, E. S.; Holmud, N. F.; Gmeiner, A.; Amar, C. F. L.; Guldimann, C.; Huynh, T. N.; Karpiskova, R.; Garcia, C. R.; Gomez, D.; Aboagye, E.; Etter, A. J.; Centorame, P.; Torresi, M.; De Angelis, M. E.; Pomilio, F.; Okholm, A. H.; Xiao, Y.; Kleta, S.; Lüth, S.; Pietzka, A. T.; Pagotto, F.; Kovacevic, J.; Rychli, K.; Zdovc, I.; Papic, B.; Heir, E.; Langsrud, S.; Moretro, T.; Roger, S.; Brown, P.; Kathariou, S.; Tasara, T.; Aarestrup, F. M.; Njage, P. M. K.; Fagerlund, A.; Truelstrup Hansen, L.; Leekitcharoenphon, P.
10.1101/2023.09.07.556668 — microbiology — Posted on 2023-09-11
3355 Targeted mutations in IFNα2 improve its antiviral activity against various viruses
Karakoese, Z.; Le-Trilling, V. T. K.; Schuhenn, J.; Francois, S.; Lu, M.; Liu, J.; Trilling, M.; Hoffmann, D.; Dittmer, U.; Sutter, K.
10.1101/2023.09.06.556557 — immunology — Posted on 2023-09-11
3356 A minimum threshold for myelination of pyramidal cells in human and mouse neocortex
Pascual Garcia, M.; Unkel, M.; Slotman, J.; bolleboom, A.; Bouwen, B.; Houtsmuller, A. B.; Dirven, C.; Gao, Z.; Hijazi, S.; Kushner, S. A.
10.1101/2023.09.09.556989 — neuroscience — Posted on 2023-09-11
3357 The chloroplastic phosphate transporter CrPHT4-7 supports phosphate homeostasis and photosynthesis in Chlamydomonas
Toth, D.; Kuntam, S.; Ferenczi, A.; Vidal-Meireles, A.; Kovacs, L.; Wang, L.; Sarkadi, Z.; Migh, E.; Szentmihalyi, K.; Tengölics, R.; Neupert, J.; Bock, R.; Jonikas, M. C.; Molnar, A.; Toth, S. Z.
10.1101/2023.09.08.556869 — plant biology — Posted on 2023-09-11
3358 Taxanes act as vascular disrupting agents and increase rate of metastasis when combined with anti-angiogenic therapy
Nandigama, R.; Kallius, M.; Hemmen, K.; Shaoli, D.; Pinnecker, J.; Ascheid, D.; Burkhard, V.; Ali, H.; Rainer, J.; Scheld, D.; Herterich, S.; Zernecke, A.; Penack, O.; Diller, S.; Camphausen, K.; Erguen, S.; Shankavaram, U.; Heinze, K.; Escorcia, F.; Henke, E.
10.1101/2022.07.18.500307 — cancer biology — Posted on 2023-09-11
3362 Loss of cholesterol in Junctional Epidermolysis Bullosa skin identifies a key role for Laminin-332 in actomyosin mediated cholesterol transport
Jones, E. M.; Camera, E.; Parzymies, P.; Marsh, S. T.; O'Shaughnessy, R. F.; Aumailley, M.; McGrath, J. A.; O'Toole, E. A.; Caley, M. P.
10.1101/2023.09.10.557030 — cell biology — Posted on 2023-09-11
3365 Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy
Zhang, Y.; Karagiannis, D.; Liu, H.; Lin, M.; Fang, Y.; Jiang, M.; Chen, X.; Suresh, S.; Huang, H.; She, J.; Shi, F.; Yang, P.; El-Rifai, W.; Zaika, A.; Oro, A. E.; Rustgi, A. K.; Wang, T. C.; Lu, C.; Que, J.
10.1101/2023.09.09.556982 — cell biology — Posted on 2023-09-11
3366 Computational exploration of the global microbiome for antibiotic discovery
Santos-Junior, C. D.; Torres, M. D. T.; Duan, Y.; Rodriguez del Rio, A.; Schmidt, T. S. B.; Chong, H.; Fullam, A.; Michael, K.; Zhu, C.; Houseman, A.; Somborski, J.; Vines, A.; Zhao, X.-M.; Bork, P.; Huerta-Cepas, J.; de la Fuente-Nunez, C.; Coelho, L. P.
10.1101/2023.08.31.555663 — microbiology — Posted on 2023-09-11
3367 Pharmacologic Stabilization of Retromer Rescues Endosomal Pathology Induced by Defects in the Alzheimer's gene SORL1
Mishra, S.; Knupp, A.; Kinoshita, C.; Williams, C. A.; Rose, S. E.; Martinez, R.; Theofilas, P.; Young, J. E.
10.1101/2022.07.31.502217 — neuroscience — Posted on 2023-09-11
3369 Claudin-2 limits pancreatitis development through regulating tight junction-controlled pancreatic ductal transport
Kesaraju, S.; Li, Y.; Tracy, M.; Wannemo, K.; Kainov, J.; Rana, N.; Sidahmed, M.; Hyoju, S.; Smith, L.; Matthews, J.; Khalili-Araghi, F.; Rana, M.; Oakes, S.; Shen, L.; Weber, C.
10.1101/2023.09.01.555960 — pathology — Posted on 2023-09-11
3370 Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS dependent apoptosis in ovarian cancer cells by targeting PAR-1
Nag, N.; Ray, T.; Tapader, R.; Gope, A.; Das, R.; Mahapatra, E.; Saha, S.; Pal, A.; Prasad, P.; Chatterjee, S.; Roy, S. S.; Pal, A.
10.1101/2023.09.06.556500 — cancer biology — Posted on 2023-09-11
3372 Phables: from fragmented assemblies to high-quality bacteriophage genomes
Mallawaarachchi, V.; Roach, M. J.; Decewicz, P.; Papudeshi, B.; Giles, S. K.; Grigson, S. R.; Bouras, G.; Hesse, R. D.; Inglis, L. K.; Hutton, A. L.; Dinsdale, E. A.; Edwards, R. A.
10.1101/2023.04.04.535632 — bioinformatics — Posted on 2023-09-11
3375 Genomic Insights into the Population History and Adaptive Traits of Latin American Criollo Cattle
Ward, J. A.; Ng'ang'a, S. I.; Randhawa, I. A. S.; McHugo, G. P.; O'Grady, J. F.; Florez, J. M.; Browne, J. A.; Perez O'Brien, A. M.; Landaeta-Hernandez, A. J.; Garcia, J. F.; Sonstegard, T. S.; Frantz, L. A. F.; Salter-Townshend, M.; MacHugh, D. E.
10.1101/2023.09.10.556512 — genomics — Posted on 2023-09-10
3379 C4 induces pathological synaptic loss by impairing AMPAR trafficking.
Phadke, R. A.; Kruzich, E.; Fournier, L. A.; Brack, A.; Sha, M.; Picard, I.; Johnson, C.; Stroumbakis, D.; Salgado, M.; Liu, Y. Y.; Cruz-Martin, A.
10.1101/2023.09.09.556388 — neuroscience — Posted on 2023-09-10
3382 Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer
Tong, X.; Patel, A. S.; Kim, E.; Li, H.; Chen, Y.; Li, S.; Liu, S.; Dilly, J.; Kapner, K. S.; Xue, Y.; Hover, L.; Mukhopadhyay, S.; Sherman, F.; Mynzdar, K.; Gao, Y.; Li, F.; Li, F.; Fang, Z.; Jin, Y.; Gao, J.; Shi, M.; Chen, L.; Chen, Y.; Kheoh, T.; Yang, W.; Yanai, I.; Moriera, A. L.; Velcheti, V.; Neel, B. G.; Hu, L.; Christensen, J. G.; Olson, P.; Gao, D.; Zhang, M. Q.; Aguirre, A. J.; Wong, K.-K.; Ji, H.
10.1101/2023.09.07.556567 — cancer biology — Posted on 2023-09-10
3385 Axial de-scanning using remote focusing in the detection arm of light-sheet microscopy
Chakraborty, T.; Dibaji, H.; SHOTORBAN, A. K. N.; HABIBI, M.; GRATTAN, R. M.; LUCERO, S.; SCHODT, D. J.; LIDKE, K. A.; PETRUCCELLI, J.; LIDKE, D. S.; LIU, S.
10.1101/2023.09.07.556729 — biophysics — Posted on 2023-09-10
3387 PI-(3,5)P2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9
Kokane, S.; Meier, P.; Gulati, A.; Matsuoka, R.; Pipatpolkai, T.; Delemotte, L.; Drew, D.
10.1101/2023.09.10.557050 — biochemistry — Posted on 2023-09-10
3390 Alternative splicing of a chromatin modifier alters the transcriptional regulatory programs of stem cell maintenance and neuronal differentiation
Nazim, M.; Lin, C.-H.; Feng, A.-C.; Yeom, K.-H.; Li, M.; Daly, A. E.; Tan, X.; Vu, H.; Ernst, J.; Carey, M. F.; Smale, S. T.; Black, D. L.
10.1101/2023.09.10.556946 — molecular biology — Posted on 2023-09-10
3391 Clinically relevant orthotopic pancreatic cancer models for adoptive T cell therapy
Horvat, N. K.; Karpovsky, I.; Wyatt, M.; Hall, M. A.; Phillips, M.; Herting, C.; Hammons, J.; Mahdi, Z.; Moffitt, R. A.; Paulos, C.; Lesinski, G. B.
10.1101/2023.09.07.556707 — cancer biology — Posted on 2023-09-10
3393 Activation mechanism of the cardiac calcium pump by a small-molecule allosteric modulator
Seflova, J.; Cruz-Cortes, C.; Guerrero-Serna, G.; Robia, S. L.; Espinoza-Fonseca, L. M.
10.1101/2023.09.07.556734 — biophysics — Posted on 2023-09-10
3394 Explainable Machine Learning Reveals the Role of the Breast Tumor Microenvironment in Neoadjuvant Chemotherapy Outcome
Azimzade, Y.; Haugen, M.; Tekpli, X.; Steen, C. B.; Fleischer, T.; Kilburn, D.; Ma, H.; Egeland, E. V.; Mills, G.; Engebraaten, O.; Kristensen, V. N.; Frigessi, A.; Kohn-Luque, A.
10.1101/2023.09.07.556655 — bioinformatics — Posted on 2023-09-10
3400 Diet influences community dynamics following vaginal group B Streptococcus colonization
Megli, C. J.; DePuyt, A. E.; Goff, J. P.; Munyoki, S. K.; Hooven, T. A.; Jasarevic, E.
10.1101/2023.09.10.556920 — microbiology — Posted on 2023-09-10
3401 Reciprocal inflammatory signals establish profibrotic cross-feeding metabolism
Yadav, P.; Gomez Ortega, J.; Chang, K.-C.; Pan, S.; Biswas, N.; Nilsson, J.; Yin, X.; Bhattacharyya, A.; Boostanpour, K.; Tsukui, T.; Sheppard, D.; Li, B.; Maishan, M.; Taenaka, H.; Matthay, M.; Muramatsu, R.; Naser, M.; Molofsky, A. B.; Wolters, P. J.; Abate, A. R.; Tharp, K.; Bhattacharya, M.
10.1101/2023.09.06.556606 — immunology — Posted on 2023-09-10
3402 Landscape of super-enhancers in small cell carcinoma of the ovary, hypercalcemic type and efficacy of targeting with natural product triptolide
Lang, J. D.; Selleck, W.; Striker, S.; Hipschman, N. A.; Kofman, R.; Karnezis, A. N.; Kommoss, F. K.; Kommoss, F.; Wendt, J. R.; Facista, S. J.; Hendricks, W. P.; Orlando, K. A.; Pirrotte, P.; Raupach, E. A.; Zismann, V. L.; Wang, Y.; Huntsman, D. G.; Weissman, B. E.; Trent, J. M.
10.1101/2023.09.08.556863 — cancer biology — Posted on 2023-09-10
3405 The glucocorticoid receptor as a master regulator of Mueller cell gliosis in the diabetic retina
Pfaller, A. M.; Kaplan, L.; Carido, M.; Grassmann, F.; Diaz-Lezama, N.; Ghaseminejad, F.; Wunderlich, K. A.; Glänzer, S.; Pannicke, T.; Weber, B. H.; Koch, S. F.; Bonev, B.; Hauck, S. M.; Grosche, A.
10.1101/2023.09.06.556478 — neuroscience — Posted on 2023-09-10
3412 Connectome spectrum electromagnetic tomography: a method to reconstruct electrical brain source-networks at high-spatial resolution
Rue Queralt, J.; Fluhr, H.; Tourbier, S.; Aleman Gomez, Y.; Pascucci, D.; Yerly, J.; Glomb, K.; Plomp, G.; Hagmann, P.
10.1101/2022.07.26.501544 — neuroscience — Posted on 2023-09-10
3415 Genetic manipulation of an Ixodes scapularis cell line
Singh, N.; Rolandelli, A.; ONeal, A. J.; Butler, L. R.; Samaddar, S.; Laukaitis-Yousey, H.; Butnaru, M.; Mohr, S. E.; Perrimon, N.; Pedra, J. H.
10.1101/2023.09.08.556855 — genetics — Posted on 2023-09-10
3421 NbPTR1 confers resistance against Pseudomonas syringae pv. actinidiae in kiwifruit
Yeh, S.-M.; Yoon, M.; Scott, S.; Chatterjee, A.; Hemara, L.; Chen, R.; Wang, T.; Templeton, K.; Rikkerink, E.; Jayaraman, J.; Brendolise, C.
10.1101/2023.09.07.556601 — plant biology — Posted on 2023-09-10
3422 Yerba mate (Ilex paraguariensis) genome provides new insights into convergent evolution of caffeine biosynthesis
Vignale, F. A.; Hernandez Garcia, A.; Modenutti, C. P.; Sosa, E. J.; Defelipe, L. A.; Oliveira, R. R. M.; Nunes, G. L.; Acevedo, R. M.; Burguener, G. F.; Rossi, M.; Zapata, P. D.; Marti, D. A.; Oliveira, G.; Smith, M. N.; Dubs, N. M.; Nair, S.; Barkman, T. J.; Turjanski, A. G.
10.1101/2023.09.08.556846 — plant biology — Posted on 2023-09-10
3427 KaryoTap Enables Aneuploidy Detection in Thousands of Single Human Cells
Mays, J. C.; Mei, S.; Bosco, N.; Zhao, X.; Bianchi, J. J.; Kidiyoor, G. R.; Holt, L. J.; Davoli, T.
10.1101/2023.09.08.555746 — genomics — Posted on 2023-09-10
3430 Haplotype independence contributes to evolvability in the long-term absence of sex in a mite
Oztoprak, H.; Gao, S.; Guiglielmoni, N.; Brandt, A.; Zheng, Y.; Becker, C.; Becker, K.; Bednarski, V.; Borgschulte, L.; Burak, K. A.; Dion-Cote, A.-M.; Leonov, V.; Opherden, L.; Shimano, S.; Bast, J.
10.1101/2023.09.07.556471 — evolutionary biology — Posted on 2023-09-10
3432 ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota
Cheng, M.-y.; Xu, B.; Sun, Y.; Wang, J.; Lu, Y.; Shi, C.; Pan, T.; Zhao, W.; Li, X.; Song, X.; Wang, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Zeng, Y.; Yang, D.; Wang, C.; Cao, X.
10.1101/2023.07.30.551192 — immunology — Posted on 2023-09-10
3435 Pharmacological or genetic inhibition of Scn9a protects beta-cells while reducing insulin secretion in type 1 diabetes
Overby, P.; Provenzano, S.; Nahirney, N. S.; Dai, X.-Q.; Sun, W. G.; Xia, Y.; Kolic, J.; Macdonald, P. E.; Johnson, J. D.
10.1101/2023.06.11.544521 — physiology — Posted on 2023-09-10
3436 Elf1 promotes Rad26 interaction with lesion-arrested Pol II for transcription-coupled repair
Sarsam, R.; Xu, J.; Lahiri, I.; Gong, W.; Oh, J.; Zhou, Z.; Chong, J.; Hao, N.; Li, S.; Wang, D.; Leschziner, A. E.
10.1101/2023.09.08.556893 — biophysics — Posted on 2023-09-10
3442 Negative allosteric modulation of the μ-opioid receptor
O'Brien, E. S.; Rangari, V. A.; El Daibani, A.; Eans, S. O.; White, B.; Wang, H.; Shiimura, Y.; Krishna Kumar, K.; Appourchaux, K.; Huang, W.; Zhang, C.; Mathiesen, J. M.; Che, T.; McLaughlin, J. P.; Majumdar, S.; Kobilka, B. K.
10.1101/2023.09.08.556921 — biochemistry — Posted on 2023-09-10
3443 Detecting shifts in the mode of chromosomal speciation across the cosmopolitan plant lineage Carex
Tribble, C. M.; Marquez Corro, J. I.; May, M. R.; Hipp, A. L.; Escudero, M.; Zenil-Ferguson, R.
10.1101/2023.09.05.556433 — evolutionary biology — Posted on 2023-09-10
3447 Targeting YAP mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology
Li, H.; Kuhn, M.; Kelly, R. A.; Singh, A.; Palanivel, K. K.; Salama, I.; De Ieso, M. L.; Stamer, W. D.; Ganapathy, P. S.; Herberg, S.
10.1101/2023.09.08.556840 — cell biology — Posted on 2023-09-10
3448 Accelerated physiology and increased energy expenditure in animals and humans with mitochondrial defects: A meta-analysis
Sercel, A. J.; Sturm, G.; Shaulson, E. D.; Gallagher, D.; St-Onge, M.-P.; Kempes, C. P.; Pontzer, H.; Hirano, M.; Picard, M.
10.1101/2023.09.09.556754 — cell biology — Posted on 2023-09-10
3449 Cytoskeletal adaptation following long-term dysregulation of actomyosin in neuronal processes
Cisterna, B. A.; Skruber, K.; Jane, M. L.; Camesi, C. I.; Nguyen, I. D.; Warp, P. V.; Black, J. B.; Butler, M. T.; Bear, J. E.; Read, T.-A.; Vitriol, E. A.
10.1101/2023.08.25.554891 — cell biology — Posted on 2023-09-10
3450 A high-content screen reveals new regulators of nuclear membrane stability
Gunn, A. L.; Yashchenko, A. I.; Dubrulle, J.; Johnson, J.; Hatch, E. L.
10.1101/2023.05.30.542944 — cell biology — Posted on 2023-09-10
3451 Modulation of riboflavin biosynthesis and utilization in mycobacteria
Chengalroyen, M. D.; Mehaffy, C.; Lucas, M.; Bauer, N.; Raphela, M. L.; Oketade, N.; Warner, D. F.; Lewinsohn, D.; Lewinsohn, D.; Dobos, K.; Mizrahi, V.
10.1101/2023.08.30.555301 — molecular biology — Posted on 2023-09-10
3453 MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus
Wang, T.; Song, D.; Li, X.; Luo, Y.; Yang, D.; Liu, X.; Kong, X.; Xing, Y.; Bi, S.; Zhang, Y.; Hu, T.; Zhang, Y.; Dai, S.; Shao, Z.; Chen, D.; Hou, J.; Ballestar, E.; Cai, J.; Zheng, F.; Yang, J. Y.
10.1101/2023.09.06.556479 — immunology — Posted on 2023-09-10
3454 Local field potentials in human motor and non-motor brain areas encode the direction of upcoming movements: An intracerebral EEG classification study
Combrisson, E.; Di Rienzo, F.; Saive, A.-l.; Perrone-Bertolotti, M.; Soto, J. L.; Kahane, P.; Lachaux, J.-P.; Guillot, A.; Jerbi, K.
10.1101/2023.09.07.556727 — neuroscience — Posted on 2023-09-10
3455 Vagus nerve stimulation recruits the central cholinergic system to enhance perceptual learning
Martin, K. A.; Papadoyannis, E. S.; Schiavo, J. K.; Shokat Fadaei, S.; Valencia, S. O.; Temiz, N. Z.; McGinley, M. J.; McCormick, D. A.; Froemke, R. C.
10.1101/2022.01.28.478197 — neuroscience — Posted on 2023-09-10
3461 Population genomics of Aspergillus sojae is shaped by the food environment
Acevedo, K. L.; Eaton, E.; Zhao, S.; Chacon-Vargas, K.; McCarthy, C. M.; Choi, D.; Yu, J.-H.; Gibbons, J. G.
10.1101/2023.09.07.556736 — evolutionary biology — Posted on 2023-09-09
3464 A General Method to Accurately Count Molecular Complexes and Determine the Degree of Labelling in Cells Using Protein Tags
Tashev, S. A.; Euchner, J.; Yserentant, K.; Hänselmann, S.; Hild, F.; Chmielewicz, W.; Hummert, J.; Schwörer, F.; Tsopoulidis, N.; Germer, S.; Sassmannshausen, Z.; Fackler, O. T.; Klingmüller, U.; Herten, D.-P.
10.1101/2023.09.08.556847 — cell biology — Posted on 2023-09-09
3465 CCR3 inhibition suppresses inflammation-driven recruitment of peripheral immune cells to the eye
Lopez, Y.; Caryotakis, S.; Raina, S.; Rege, S. V.; Harish, R.; Ray, R.; Kosti, I.; Teichert, A.; Minami, S. S.; Dhande, O.
10.1101/2023.09.08.556878 — cell biology — Posted on 2023-09-09
3466 Visualizing interactions of VDAC1 in live cells using a tetracysteine tag
Pilic, J.; Oflaz, F. E.; Gottschalk, B.; Erdogan, Y. C.; Graier, W. F.; Malli, R.
10.1101/2023.09.08.556841 — cell biology — Posted on 2023-09-09
3468 Progesterone induces meiosis through two obligate co-receptors with PLA2 activity
Nader, N.; Zarif, L.; Halama, A.; Yadav, S.; Dib, M.; Attarwala, N.; Chen, Q.; Suhre, K.; Gross, S. S.; Machaca, K.
10.1101/2023.09.09.556646 — cell biology — Posted on 2023-09-10
3469 Influence of FTDP-17 mutants on circTau RNAs
Margvelani, G.; Welden, J. R.; Arizaca Maquera, K. A.; Miranda Sardon, S.; Stamm, S.
10.1101/2023.09.08.556913 — molecular biology — Posted on 2023-09-09
3473 Inhibition of Parkinsons Disease-related LRRK2 by type-I and type-II kinase inhibitors: activity and structures
Leschziner, A. E.; Sanz Murillo, M.; Suarez, A. V.; Dederer, V.; Chatterjee, D.; Louro, J. A.; Knapp, S.; Mathea, S.
10.1101/2023.09.07.556689 — biophysics — Posted on 2023-09-09
3476 A model for the dynamics of expanded CAG repeat alleles: ATXN2 and ATXN3 as prototypes
Sena, L. S.; Lemes, R. B.; Furtado, G. V.; Saraiva-Pereira, M. L.; Jardim, L. B.
10.1101/2023.09.07.556735 — genetics — Posted on 2023-09-09
3479 Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation
Anoud, M.; Delagoutte, E.; Helleu, Q.; Brion, A.; Duvernois-Berthet, E.; As, M.; Marques, X.; Lamribet, K.; Senamaud, C.; Jourdren, L.; Adrait, A.; Heinrich, S.; Toutirais, G.; Hamlaoui, S.; Gropplero, G.; Ponger, L.; Geze, M.; Blugeon, C.; Coute, Y.; Guidetti, R.; Rebecchi, L.; Giovannangeli, C.; De Cian, A.; Concordet, J.-P.
10.1101/2023.09.08.556854 — molecular biology — Posted on 2023-09-09
3481 Tradeoffs of increasing temperatures for the spread of antimicrobial resistance in river biofilms
Bagra, K.; Kneis, D.; Padfield, D.; Szekeres, E.; Teban-Man, A.; Coman, C.; Singh, G.; Berendonk, T. U.; Klümper, U.
10.1101/2023.09.08.556853 — microbiology — Posted on 2023-09-09
3484 Potential of Ilheus virus to emerge
Plante, K. S.; Plante, J. A.; Azar, S. R.; Shinde, D. P.; Scharton, D.; Versiani, A. F.; Oliveira da Silva, N. I.; Strange, T.; Sacchetto, L.; Fokam, E. B.; Rossi, S. L.; Weaver, S.; Marques, R. E.; Nogueira, M. L.; Vasilakis, N.
10.1101/2023.09.08.556909 — microbiology — Posted on 2023-09-09
3485 Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders
Buzas, D.; Sun, H.; Toelzer, C.; Yadav, S. K. N.; Borucu, U.; Gautam, G.; Gupta, K.; Bufton, J.; Capin, J.; Sessions, R. B.; Garzoni, F.; Berger, I.; Schaffitzel, C.
10.1101/2023.09.09.556966 — synthetic biology — Posted on 2023-09-09
3486 Poverty shapes the transcriptome of immune cells
Arnold, N. S.; Resztak, J.; Witonsky, D.; Alazizi, A.; Hooten, N. N.; Evans, M. K.; Odera-Marah, V.; Dluzen, D. F.; Pique-Regi, R.; Luca, F.
10.1101/2022.12.06.517536 — genomics — Posted on 2023-09-09
3489 Exploratory Correlation of The Human Structural Connectome with Non-MRI Variables in Alzheimer's Disease
Aganj, I.; Mora, J.; Frau-Pascual, A.; Fischl, B. R.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.06.30.547308 — neuroscience — Posted on 2023-09-09
3494 Trans-Omics analysis of post injury thrombo-inflammation identifies endotypes and trajectories in trauma patients.
Cohen, M. J.; Erickson, C. B.; Lacroix, I. S.; Debot, M.; Dzieciatkowska, M.; Schaid, T. R.; Hallas, M. W.; Thielen, O. N.; Cralley, A. L.; Banerjee, A.; Moore, E. E.; Silliman, C. C.; D'Alessandro, A.; Hansen, K. C.
10.1101/2023.08.16.553446 — biochemistry — Posted on 2023-09-09
3495 Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease
D'Oliviera, A.; Dai, X.; Mottaghinia, S.; Geissler, E. P.; Etienne, L.; Zhang, Y.; Mugridge, J. S.
10.1101/2023.02.20.529306 — biochemistry — Posted on 2023-09-09
3496 Cities as parasitic amplifiers? Malaria prevalence and diversity along an urbanization gradient in great tits
Caizergues, A. E.; Robira, B.; Perrier, C.; Jeanneau, M.; Berthomieu, A.; Perret, S.; Gandon, S.; Charmantier, A.
10.1101/2023.05.03.539263 — ecology — Posted on 2023-09-09
3498 Characterisation of TbSmee1 indicates that endocytosis is required for access of surface-bound cargo to the trypanosome flagellar pocket
Schichler, D.; Spath, E.-M.; Konle, A.; Riegler, S.; Klein, A.; Seleznev, A.; Jung, S.; Wuppermann, T.; Wetterich, N.; Borges, A.; Meyer-Natus, E.; Havlicek, K.; Cabrera, S. P.; Niedermueller, K.; Sajko, S.; Dohn, M.; Malzer, X.; Riemer, E.; Tumurbaatar, T.; Djinovic-Carugo, K.; Dong, G.; Janzen, C. J.; Morriswood, B.
10.1101/2022.03.15.484455 — cell biology — Posted on 2023-09-09
3499 A Small Tau Fragment Specifically Templates Four Repeat Tau Aggregates Through Multiple Generations
Longhini, A. P.; DuBose, A.; Lobo, S.; Vijayan, V.; Bai, Y.; Keane, E.; Sala-Jarque, J.; Nikitina, A.; Carrettiero, D.; Unger, M.; Sclafani, O.; Fu, V.; Vigers, M.; Buee, L.; Landrieu, I.; Shell, S.; Shea, J. E.; Han, S.; Kosik, K. S.
10.1101/2023.08.31.555649 — molecular biology — Posted on 2023-09-09
3500 Alfalfa vein mottling virus, a novel potyvirid infecting Medicago sativa L.
Nemchinov, L. G.; Postnikova, O. A.; Wintermantel, W. M.; Palumbo, J. C.; Grinstead, S.
10.1101/2023.09.07.556681 — microbiology — Posted on 2023-09-09
3506 Identification of 1600 replication origins in S. cerevisiae
Foss, E. J.; Lichauco, C.; Gatbonton-Schwager, T.; Lofts, B.; Lao, U.; Bedalov, A.
10.1101/2023.04.11.536402 — genetics — Posted on 2023-09-09
3507 The global distribution of angiosperm genome size is shaped by climate
Bures, P.; Elliott, T. L.; Vesely, P.; Smarda, P.; Forest, F.; Leitch, I. J.; Lughadha, E. N.; Gomez, M. S.; Pironon, S.; Brown, M. J. M.; Smerda, J.; Zedek, F.
10.1101/2022.12.05.519116 — evolutionary biology — Posted on 2023-09-09
3510 Insights into Digit Evolution from a Fate Map Study of the Forearm
Oh, J. D. H.; Saunders, D. D. Z.; McTeir, L.; Jackson, M.; Glover, J. D.; Schoenebeck, J. J.; Lettice, L. A.; Davey, M. G.
10.1101/2023.08.29.555165 — developmental biology — Posted on 2023-09-09
3512 To Smooth or not to Smooth: Enhancing Specificity While Maintaining Sensitivity
Luders, E.; Dahnke, R.; Gaser, C.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2022.06.11.495739 — neuroscience — Posted on 2023-09-09
3514 BrainAGE: Revisited and reframed machine learning workflow
Kalc, P.; Dahnke, R.; Hoffstaedter, F.; Gaser, C.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2022.11.21.517386 — neuroscience — Posted on 2023-09-09
3519 Post-Mating Inhibition of Female Sexual Drive via Heterogeneous Neuronal Ensembles in the Medial Preoptic Area
Ishii, K. K.; Hashikawa, K.; Chea, J.; Yin, S.; Fox, R. E.; Kan, S.; Zhou, C.; Navarrete, J.; Murry, A. D.; Szelenyi, E.; Golden, S.; Stuber, G.
10.1101/2023.09.08.556711 — neuroscience — Posted on 2023-09-09
3522 Identification of functional white matter networks in BOLD fMRI
Eby, A. L.; Remedios, L. W.; Kim, M. E.; Li, M.; Gao, Y.; Gore, J.; Schilling, K.; Landman, B. A.
10.1101/2023.09.08.556881 — neuroscience — Posted on 2023-09-09
3523 Neural correlates of future volitional action in Drosophila
Brezovec, L. E.; Berger, A. B.; Druckmann, S.; Clandinin, T. R.
10.1101/2023.09.08.556917 — neuroscience — Posted on 2023-09-09
3525 Gaining proficiency in flight transforms energy landscapes during ontogeny
Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.
10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2023-09-09
3527 Identification of amnion progenitor-like cells at the amnion-epiblast boundary in the primate peri-gastrula
Sekulovski, N.; Juga, L. L.; Cortez, C. L.; Czerwinski, M.; Whorton, A. E.; Spence, J. R.; Kropp Schmidt, J.; Golos, T.; Gumucio, D. L.; Lin, C.-W.; Taniguchi, K.
10.1101/2023.09.07.556553 — developmental biology — Posted on 2023-09-09
3528 "Surviving and Thriving": Evidence for Cortical GABA Stabilization in Cognitively-Intact Oldest-Old Adults
Britton, M. K.; Jensen, G.; Edden, R. A.; Puts, N. A.; Nolin, S. A.; Merritt, S. S.; Rezaei, R. F.; Forbes, M.; Johnson, K. J.; Bharadwaj, P.; Franchetti, M. K.; Raichlen, D. A.; Jessup, C. J.; Hishaw, G. A.; Van Etten, E. J.; Gudmundson, A. T.; Murali-Manohar, S.; Cowart, H.; Trouard, T. P.; Geldmacher, D. S.; Wadley, V. G.; Alperin, N.; Levin, B. E.; Rundek, T.; Visscher, K. M.; Woods, A. J.; Alexander, G. E.; Cohen, R. A.; Porges, E. C.
10.1101/2023.09.08.556410 — neuroscience — Posted on 2023-09-09
3530 Learning site-invariant features of connectomes to harmonize complex network measures
Newlin, N. R.; Kanakaraj, P.; Li, T. Z.; Pechman, K.; Archer, D. B.; Jefferson, A.; Landman, B. A.; Moyer, D.
10.1101/2023.09.07.556721 — neuroscience — Posted on 2023-09-09
3531 Development of a cellular reporter assay to measure activity of MutSβ, a therapeutic target for Huntington's disease
An, J.; Towle, T.; Aksit, M. A.; Mohiuddin, M.; Castaneda, S.; Nakashima, R.; Moccia, R.; Bulawa, C.; Fleming, J.
10.1101/2023.09.07.555786 — neuroscience — Posted on 2023-09-09
3533 Assessing cortical excitability with electroencephalography: a pilot study with EEG-iTBS.
Pellegrino, G.; Schuler, A.-L.; Cai, Z.; Marinazzo, D.; Tecchio, F.; Ricci, L.; Tombini, M.; Di Lazzaro, V.; Assenza, G.
10.1101/2023.09.08.556829 — neuroscience — Posted on 2023-09-09
3534 TRPM2-CaMKII signaling drives excessive GABAergic synaptic inhibition following ischemia
Burch, A. M.; Garcia, J. D.; O'Leary, H.; Haas, A.; Orfila, J. E.; Tiemeier, E.; Chalmers, N.; Smith, K. R.; Quillinan, N.; Herson, P. S.
10.1101/2023.09.07.556550 — neuroscience — Posted on 2023-09-09
3537 Sound elicits stereotyped facial movements that provide a sensitive index of hearing abilities
Clayton, K. K.; Stecyk, K. S.; Guo, A. A.; Chambers, A. R.; Chen, K.; Hancock, K. E.; Polley, D. B.
10.1101/2023.09.07.556766 — neuroscience — Posted on 2023-09-09
3538 An adapted stem cell-derived microglia protocol for the study of microgliopathies and other neurological disorders
Dorion, M.-F.; Casas, D.; Yaqubi, M.; Fleming, P.; Chen, C. X.- Q.; Piscopo, V. E. C.; Nicouleau, M.; Goldsmith, T. M.; Shlaifer, I.; MacDonald, A.; Dudley, R. W. R.; Hall, J. A.; Antel, J. P.; Stratton, J. A.; Durcan, T. M.; La Piana, R.; Healy, L. M.
10.1101/2023.09.08.556933 — neuroscience — Posted on 2023-09-09
3539 Seeding Activity of Skin Misfolded Tau as a Novel Biomarker for Tauopathies
Wang, Z.; Wu, L.; Gerasimenko, M.; Gilliland, T.; Shah, Z. S. A.; Gunzler, S. A.; Donadio, V.; Liguori, R.; Xu, B.; Zou, W.
10.1101/2023.09.07.556724 — neuroscience — Posted on 2023-09-09
3540 SignEEG v1.0 : Multimodal Electroencephalography and Signature Database for Biometric Systems
Mishra, A. R.; Kumar, R.; Gupta, V.; Prabhu, S.; Upadhyay, R.; Chhipa, P. C.; Rakesh, S.; Mokayed, H.; Liwicki, M.; Liwicki, F. S.; Saini, R.
10.1101/2023.09.09.556960 — neuroscience — Posted on 2023-09-09
3542 Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to naloxone administration
Bedard, M. L.; Murray, J. G.; Huang, X.-P.; Nowlan, A. C.; Conley, S. Y.; E, M. S.; Loyack, S. J.; Cline, C. A.; Clodfelter, C. G.; Dasgupta, N.; Roth, B. L.; McElligott, Z. A.
10.1101/2023.09.08.556914 — neuroscience — Posted on 2023-09-09
3543 Translational modulation by ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome
Coulson, R.; Frattini, V.; Moyer, C.; Hodges, J.; Walter, P.; Mourrain, P.; Zuo, Y.; Wang, G.
10.1101/2023.09.08.553269 — neuroscience — Posted on 2023-09-09
3544 How does V1 population activity inform perceptual certainty?
Boundy-Singer, Z. M.; Ziemba, C. M.; Henaff, O. J.; Goris, R. L. T.
10.1101/2023.09.08.556926 — neuroscience — Posted on 2023-09-09
3545 The influence of chronological age and menopause status on the functional neural correlates of spatial context memory in middle-aged females.
Crestol, A.; Rajagopal, S.; Lissaman, R.; LaPlume, A.; Pasvanis, S.; Olsen, R.; Einstein, G.; Jacobs, E. G.; Rajah, M. N.
10.1101/2023.09.06.556387 — neuroscience — Posted on 2023-09-09
3547 Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
Devkota, S.; Zhou, R.; Nagarajan, V.; Maesako, M.; Do, H.; Noorani, A.; Overmeyer, C.; Bhattarai, S.; Douglas, J. T.; Saraf, A.; Miao, Y.; Ackley, B. D.; Shi, Y.; Wolfe, M. S.
10.1101/2023.09.08.556905 — neuroscience — Posted on 2023-09-09
3549 Probing the Mechanisms of Global Brain Reconfiguration after Local Manipulations
Rabuffo, G.; Lokossou, H.-A.; Li, Z.; Ziaee-Mehr, A.; Hashemi, M.; Quilichini, P. P.; Ghestem, A.; Arab, O.; Esclapez, M.; Verma, P.; Raj, A.; Gozzi, A.; Sorrentino, P.; Chuang, K.-H.; Perles-Barbacaru, T.-A.; Viola, A.; Jirsa, V. K.; Bernard, C.
10.1101/2023.09.08.556815 — neuroscience — Posted on 2023-09-09
3550 Shorter reported sleep duration in men is associated with worse virtual spatial navigation performance
Yavuz, E.; Lazar, A. S.; Gahnstrom, C. J.; Goodroe, S.; Coutrot, A.; Hornberger, M.; Spiers, H. J.
10.1101/2023.09.09.556942 — neuroscience — Posted on 2023-09-09
3551 Microglial 25-hydroxycholesterol mediates neuroinflammation and neurodegeneration ina tauopathy mouse model
Toral-Rios, D.; Long, J. M.; Ulrich, J. D.; Yu, J.; Strickland, M. R.; Han, X.; Holtzman, D. M.; CASHIKAR, A. G.; Paul, S. M.
10.1101/2023.09.08.556884 — neuroscience — Posted on 2023-09-09
3552 Olfactory-to-visual facilitation in the infant brain declines gradually from 4 to 12 months
Rekow, D.; Baudouin, J.-Y.; Kiseleva, A.; Rossion, B.; Durand, K.; Schaal, B.; Leleu, A.
10.1101/2023.09.08.556823 — neuroscience — Posted on 2023-09-09
3554 Unveiling a Novel Memory Center in Humans: Neurochemical Identification of the Nucleus Incertus, a Key Pontine Locus Implicated in Stress and Neuropathology
de Avila, C.; Gugula, A.; Trenk, A.; Intorcia, A. J.; Suazo, C.; Nolz, J.; Plamondon, J.; Khatri, D.; Tallant, L.; Caron, A.; Blasiak, A.; Serrano, G. E.; Beach, T. G.; Gundlach, A. L.; Mastroeni, D.
10.1101/2023.09.08.556922 — neuroscience — Posted on 2023-09-09
3558 Hippocampal connectivity patterns echo macroscale cortical evolution in the primate brain
Eichert, N.; DeKraker, J.; Howard, A. F. D.; Huszar, I. N.; Zhu, S.; Sallet, J.; Miller, K. L.; Mars, R. B.; Jbabdi, S.; Bernhardt, B. C.
10.1101/2023.09.08.556859 — neuroscience — Posted on 2023-09-09
3560 Converging Topographic Axes of Connectivity and Genetic Architectures Scaffold Cortical Patterning
Li, D.; Ma, L.; Wang, Y.; Lu, Y.; Wang, H.; Wang, Y.; Gao, C.; Cheng, L.; Zhang, Y.; Yang, Z.; Eickhoff, S.; Chen, C.-h.; Chu, C.; Fan, L.
10.1101/2023.09.06.556618 — neuroscience — Posted on 2023-09-09
3562 Critical Behavioral Traits Foster Peer Engagement in Online Mental Health Communities
Srivastava, A.; Gupta, T.; Cerezo, A.; Lord, S. P.; Akhtar, M. S.; Chakraborty, T.
10.1101/2023.09.06.556577 — neuroscience — Posted on 2023-09-08
3564 Toward a synthesis of phytoplankton community composition methods for global-scale application
Kramer, S. J.; Bolanos, L. M.; Catlett, D.; Chase, A. P.; Behrenfeld, M. J.; Boss, E. S.; Crockford, E. T.; Giovannoni, S. J.; Graff, J. R.; Haëntjens, N.; Karp-Boss, L.; Peacock, E. E.; Roesler, C. S.; Sosik, H. M.; Siegel, D. A.
10.1101/2023.09.07.556589 — ecology — Posted on 2023-09-08
3567 PAN-GWES: Pangenome-spanning epistasis and co-selection analysis via de Bruijn graphs
Kuronen, J.; Horsfield, S.; Pontinen, A. K.; Arredondo-Alonso, S.; Thorpe, H.; Gladstone, R.; Willems, R. J. L.; Bentley, S. D.; Croucher, N. J.; Pensar, J.; Lees, J. A.; Tonkin-Hill, G.; Corander, J.
10.1101/2023.09.07.556769 — bioinformatics — Posted on 2023-09-08
3568 Genome-wide Perturbation Analysis Screening System for Exosomes-Related Genes Based on the CRISPR/Cas9 Platform
Lu, L.; Yin, J.; Chen, N.; Guo, X.; Han, C.; Wang, M.; Du, H.; Li, H.; Pan, X.; Gao, M.; Wang, N.; Qi, D.; Wang, J.; Dong, F.; Li, T.; Ge, X.
10.1101/2023.09.07.556640 — bioengineering — Posted on 2023-09-08
3570 Dynamic atP5CS2 Filament Facilitates Substrate Channeling
Guo, C.-J.; Zhang, T.; Leng, Q.; Zhou, X.; Zhong, J.; Liu, J.-L.
10.1101/2023.09.07.556688 — biochemistry — Posted on 2023-09-08
3571 An efficient peptide ligase engineered from a bamboo asparaginyl endopeptidase
Wang, X.-B.; Zhang, C.-H.; Zhang, T.; Li, H.-Z.; Liu, Y.-L.; Xu, Z.-G.; Lei, G.; Cai, C.-J.; Guo, Z.-Y.
10.1101/2023.09.07.556767 — biochemistry — Posted on 2023-09-08
3572 Conformational changes in the Niemann-Pick Type C1 protein NCR1 drive sterol translocation
Frain, K. M.; Dedic, E.; Nel, L.; Bohush, A.; Olesen, E.; Stokes, D. L.; Pedersen, B. P.
10.1101/2023.09.08.556848 — biochemistry — Posted on 2023-09-08
3574 The crystal and cryo-EM structures of PLCγ2 reveal dynamic inter-domain recognitions in autoinhibition
Shin, Y.-C.; Plummer-Medeiros, A. M.; Mungenast, A.; Choi, H.-w.; TenDyke, K.; Zhu, X.; Shepard, J.; Zhuang, N.; Hu, L.; Qian, D.; Song, K.; Xu, C.; Wang, J.; Poda, S. B.; Liao, M.; Chen, Y.
10.1101/2023.09.07.556539 — biochemistry — Posted on 2023-09-08
3576 Molecular model of a bacterial flagellar motor in situ reveals a "parts-list" of protein adaptations to increase torque
Drobnic, T.; Cohen, E. J.; Alzheimer, M.; Froschauer, K.; Svensson, S.; Singh, N.; Garg, S. G.; Henderson, L.; Umrekar, T.; Nans, A.; Ribardo, D.; Hochberg, G.; Hendrixson, D. R.; Sharma, C. M.; Rosenthal, P.; Beeby, M.
10.1101/2023.09.08.556779 — molecular biology — Posted on 2023-09-08
3578 A dynamic bias in chromatin protein deposition at G-quadruplex sites
Lobo, T.; Chen, D.; Zwinderman, M.; Lansdorp, P.; Dekker, F. J.; Guryev, V.
10.1101/2023.09.08.556515 — molecular biology — Posted on 2023-09-08
3580 CCG-1423-derived compounds reduce global RNA synthesis and inhibit transcriptional responses
Prajapati, B. K.; Sokolova, M.; Sidorenko, E.; Kyriacou, M.; Kyheroinen, S.; Vihervaara, A.; Vartiainen, M. K.
10.1101/2023.09.08.556810 — molecular biology — Posted on 2023-09-08
3581 Differential Carbonic Anhydrase Activities Control EBV-Induced B-Cell Transformation and Lytic Cycle Reactivation
Malik, S.; Biswas, J.; Sarkar, P.; Nag, S.; Gain, C.; Ghosh Roy, S.; Bhattacharya, B.; Ghosh, D.; Saha, A.
10.1101/2023.09.08.556787 — microbiology — Posted on 2023-09-08
3582 Evolution of a large periplasmic disk in Campylobacterota flagella facilitated efficient motility alongside autoagglutination
Cohen, E. J.; Drobnic, T.; Yoshioka, A.; Umrekar, T.; Brock, E.; Ribardo, D.; Guo, X.; Fernandez, J.-J.; Nakane, D.; Wilson, L.; Hendrixson, D. R.; Beeby, M.
10.1101/2023.09.08.556628 — microbiology — Posted on 2023-09-08
3583 Automated workflow for BioID improves reproducibility and identification of protein-protein interactions
Cirri, E.; Knaudt, H.; Di Fraia, D.; Poempner, N.; Rahnis, N.; Heinze, I.; Ori, A.; Dau, T.
10.1101/2023.09.08.556804 — biochemistry — Posted on 2023-09-08
3584 Identification of an H-Ras nanocluster disrupting peptide
Manoharan, G. b.; Steffen, C. L.; Pavic, K.; Yeste-Vazquez, A.; Knuuttila, M.; Arora, N.; Zhou, Y.; Harma, H.; Gaigneaux, A.; Grossmann, T. N.; Abankwa, D. K.
10.1101/2023.09.07.556635 — biochemistry — Posted on 2023-09-08
3585 Novel laminarin-binding CBMs in multimodular proteins of marine Bacteroidota feature prominently in phytoplankton blooms
Zuehlke, M.-K.; Ficko-Blean, E.; Bartosik, D.; Terrapon, N.; Jeudy, A.; Jam, M.; Wang, F.; Welsch, N.; Larocque, R.; Jouanneau, D.; Eisenack, T.; Thomas, F.; Trautwein-Schult, A.; Teeling, H.; Becher, D.; Schweder, T.; Czjzek, M.
10.1101/2023.09.07.556657 — biochemistry — Posted on 2023-09-08
3588 SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression
Frieman, M.; McGrath, M. E.; Xue, Y.; Taylor, L.; Dillen, C.; Ardanuy, J.; Gonzalez-Juarbe, N.; Baracco, L.; Kim, R.; Hart, R.; Assad-Garcia, N.; Vashee, S.
10.1101/2023.09.08.556788 — microbiology — Posted on 2023-09-08
3589 Stereotypic persistent B cell receptor clonotypes in Alzheimer's Disease
Yang, H.; Kim, N.; Lee, Y.; Yoo, D. K.; Choi, J.; Kim, K.; Bae, J.; Han, J.; Kwon, S.; Chung, J.
10.1101/2023.09.07.554570 — immunology — Posted on 2023-09-08
3590 The Bacterial Replicative Helicase Loader DciA is a DNA Condenser.
Marsin, S.; Jeannin, S.; Baconnais, S.; Walbott, H.; Pehau-Arnaudet, G.; Noiray, M.; Aumont-Nicaise, M.; Stender, E. G.; Cargemel, C.; Le Bars, R.; Le Cam, E.; Quevillon-Cheruel, S.
10.1101/2023.09.08.556801 — biochemistry — Posted on 2023-09-08
3591 Estrogen receptor activation remodels TEAD1 gene expression to alleviate nonalcoholic fatty liver disease
Sommerauer, C.; Gallardo-Dodd, C. J.; Savva, C.; Hases, L.; Birgersson, M.; Indukuri, R.; Shen, J. X.; Carravilla, P.; Geng, K.; Norskov Sondergaard, J.; Ferrer-Aumatell, C.; Mercier, G.; Sezgin, E.; Korach-Andre, M.; Petersson, C.; Hagstrom, H.; Lauschke, V. M.; Archer, A.; Williams, C.; Kutter, C.
10.1101/2023.09.07.556687 — genomics — Posted on 2023-09-08
3593 Unveiling the ecology, taxonomy and metabolic capabilities of MBA03, a potential key player in anaerobic digestion
Puchol-Royo, R.; Pascual, J.; Ortega-Legarreta, A.; Otto, P.; Tideman, J.; de Vries, S.-J.; Abendroth, C.; Tanner, K.; Porcar, M.; Latorre-Perez, A.
10.1101/2023.09.08.556800 — ecology — Posted on 2023-09-08
3595 Multivariate comparison of taxonomic, chemical and technical data from 80 full-scale an-aerobic digester-related systems
Otto, P.; Puchol-Royo, R.; Ortega-Legarreta, A.; Tanner, K.; Tideman, J.; de Vries, S.-J.; Pascual, J.; Porcar, M.; Latorre-Perez, A.; Abendroth, C.
10.1101/2023.09.08.556802 — microbiology — Posted on 2023-09-08
3596 A soybean rust effector protease suppresses host immunity and cleaves a 3-deoxy-7-phosphoheptulonate synthase
Chicowski, A. S.; Qi, M.; Variz, H.; Bredow, M.; Montes-Serey, C.; Caiazza, F.; Dong, H.; Margets, A. C.; Mejias, J.; Walley, J.; Craik, C.; Pedley, K. F.; Aung, K.; Innes, R. W.; Whitham, S.
10.1101/2023.09.07.556260 — plant biology — Posted on 2023-09-08
3598 MetFinder: a neural network-based tool for automated quantitation of metastatic burden in histological sections from animal models
Karz, A.; Coudray, N.; Bayraktar, E.; Galbraith, K.; Jour, G.; Shadaloey, A. A. S.; Eskow, N.; Rubanov, A.; Navarro, M.; Moubarak, R.; Baptiste, G.; Levinson, G.; Mezzano, V.; Alu, M.; Loomis, C.; Lima, D.; Rubens, A.; Jilaveanu, L.; Tsirigos, A.; Hernando, E.
10.1101/2023.09.07.555360 — cancer biology — Posted on 2023-09-08
3599 Deep learning-assisted single-molecule detection of protein post-translational modifications with a biological nanopore
Cao, C.; Magalhaes, P.; Krapp, L.; Bada Juarez, J.; Mayer, S.; Rukes, V.; Chiki, A.; Lashuel, H.; Dal Peraro, M.
10.1101/2023.09.08.555904 — biophysics — Posted on 2023-09-08
3604 Periodic shifts in viral load increase risk of spillover from bats
Lunn, T. J.; Borremans, B.; Jones, D. N.; Kessler, M. K.; Dale, A. S.; Yinda, K. C.; Ruiz-Aravena, M.; Falvo, C. A.; Crowley, D.; Lloyd-Smith, J. O.; Munster, V. J.; Eby, P.; McCallum, H.; Hudson, P.; Restif, O.; McGuire, L. P.; Smith, I. L.; Bat One Health Group, ; Plowright, R. K.; Peel, A. J.
10.1101/2023.09.06.556454 — ecology — Posted on 2023-09-08
3608 Tissue-resident uterine regulatory T cells support fetal growth
Florez, L. M.; Fourcade, G.; Darrasse-Jeze, G.; Barennes, P.; Gan-Fernandez, K.; Regnier, P.; Nehar-Belaid, D.; Courau, T.; Ruocco, M. G.; Zacchigna, S.; Giacca, M.; Lion, J.; Mooney, N.; Tchitchek, N.; Mariotti-Ferrandiz, E.; Klatzmann, D.
10.1101/2023.09.07.554921 — immunology — Posted on 2023-09-08
3609 Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability
Wethington, D.; Potempa, M.; Giuliani, G.; Aguilar, O. A.; Grassmann, S.; Stewart, W.; Adams, N. M.; Sun, J. C.; Lanier, L. L.; Das, J.
10.1101/2023.09.07.556760 — immunology — Posted on 2023-09-08
3610 Ketogenic diet administration later in life improves memory and regulates the synaptic cortical proteome through the cAMP/PKA signaling pathway in aging mice.
Acuna-Catalan, D.; Shah, S.; Wehrfritz, C.; Nomura, M.; Acevedo, A.; Olmos, C.; Quiroz, G.; Huerta, H.; Bons, J.; Ampuero, E.; Wyneken, U.; Sanhueza, M.; Arancibia, F.; Contreras, D.; Cardenas, J. C.; Morales, B.; Schilling, B.; Newman, J. C.; Gonzalez-Billault, C.
10.1101/2023.09.07.556691 — neuroscience — Posted on 2023-09-08
3617 MacaqueNet: big-team research into the biological drivers of social relationships
De Moor, D.; MacaqueNet, ; Skelton, M.; Schulke, O.; Ostner, J.; Neumann, C.; Duboscq, J.; Brent, L. J. N.
10.1101/2023.09.07.552971 — animal behavior and cognition — Posted on 2023-09-08
3618 Gestures Of Hunger: Uncovering Intentional Gestural Communication In Free-Ranging Hanuman Langurs
Dasgupta, D.; Banerjee, A.; Dutta, A.; Mitra, S.; Banerjee, D.; Karar, R.; Karmakar, S.; Bhattacharya, A.; Ghosh, S.; Bhattacharjee, P.; Paul, M.
10.1101/2023.09.07.552163 — animal behavior and cognition — Posted on 2023-09-08
3619 Resolution of ring chromosomes, Robertsonian translocations, and complex structural variants from long-read sequencing and telomere-to-telomere assembly
Mostovoy, Y.; Boone, P. M.; Huang, Y.; Garimella, K. V.; Tan, K.-T.; Russell, B. E.; Salani, M.; Curall, B.; Lucente, D.; Bowers, T.; DeSmet, T.; Gabriel, S.; Morton, C. C.; Meyerson, M.; Gusella, J.; Quintero-Rivera, F.; Brand, H.; Talkowski, M. E.
10.1101/2023.09.07.555775 — genomics — Posted on 2023-09-08
3620 A beneficial synonymous substitution in EF-Tu is contingent on genetic background
McGrath, K. M.; Russell, S.; Fer, E.; Garmendia, E.; Hosgel, A.; Baltrus, D.; Kacar, B.
10.1101/2023.09.06.555949 — evolutionary biology — Posted on 2023-09-08
3621 Thermal and Nutrient Stress Drove Permian-Triassic Marine Extinctions
Foster, W. J.; Frank, A. B.; Li, Q.; Danise, S.; Wang, X.; Peckmann, J.
10.1101/2023.09.08.556797 — evolutionary biology — Posted on 2023-09-08
3623 Hippo-deficient cardiac fibroblasts differentiate into osteochondroprogenitors
Tsai, C.-R.; Kim, J.; Li, X.; Czarnewski Barenco, P. V.; Li, R.; Meng, F.; Zheng, M.; Zhao, X.; Steimle, J.; Grisanti, F.; Wang, J.; Samee, M. A. H.; Martin, J. F.
10.1101/2023.09.06.556593 — developmental biology — Posted on 2023-09-08
3624 Neurovascular Mechanisms of Cognitive Aging: Arteriosclerosis Precipitates Demyelination and Cognitive Decline
Bowie, D. C.; Low, K. A.; Rubenstein, S. L.; Islam, S. S.; Zimmerman, B.; Sutton, B. P.; Gratton, G.; Fabiani, M.
10.1101/2023.09.06.556562 — neuroscience — Posted on 2023-09-08
3627 Rapid, biochemical tagging of cellular activity history in vivo
Zhang, R.; Anguiano, M.; Aarrestad, I. K.; Lin, S.; Chandra, J.; Vadde, S. S.; Olson, D. E.; Kim, C. K.
10.1101/2023.09.06.556431 — neuroscience — Posted on 2023-09-08
3630 Targeting tumour-intrinsic neural vulnerabilities of glioblastoma
Lee, S.; Weiss, T.; Buehler, M.; Mena, J.; Lottenbach, Z.; Wegmann, R.; Sun, M.; Bihl, M.; Augustynek, B.; Baumann, S.; Goetze, S.; van Drogen, A.; Pedrioli, P.; Kirschenbaum, D.; Vasella, F.; Rushing, E. J.; Wollscheid, B.; Hediger, M. A.; Weller, M.; Snijder, B.
10.1101/2022.10.07.511321 — cancer biology — Posted on 2023-09-08
3631 Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer
Graham, M. K.; Wang, R.; Chikarmane, R.; Wodu, B.; Vaghasia, A.; Gupta, A.; Zheng, Q.; Hicks, J.; Sysa-Shah, P.; Pan, X.; Castagna, N.; Liu, J.; Meyers, J.; Skaist, A.; Zhang, Y.; Schuebel, K.; Simons, B.; Bieberich, C. J.; Nelson, W.; Lupold, S. E.; DeWeese, T. L.; De Marzo, A. M.; Yegnasubramanian, S.
10.1101/2023.09.07.553268 — cancer biology — Posted on 2023-09-08
3632 Enhancer-driven regulatory network of forebrain human development provides insights into autism
Vaccarino, F. M.; Jourdon, A.; Mariani, J.; Wu, F.; Capauto, D.; Norton, S.; Tomasini, L.; Amiri, A.; Schreiner, J.; Nguyen, C. K.; Nolan, N.; Szekely, A.; McPartland, J. C.; Pelphrey, K.; Chawarska, K.; Ventola, P.; Abyzov, A.
10.1101/2023.09.06.555206 — genomics — Posted on 2023-09-08
3634 THE STRUCTURE OF DNA IN ANABIOTIC AND MUMMIFIED CELLS
Krupyanskii, Y. F.; Kovalenko, V. F.; Loiko, N.; Tereshkin, E. V.; Tereshkina, K.; Popov, A. N.
10.1101/2023.09.07.556722 — cell biology — Posted on 2023-09-08
3635 Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells
Hindul, N. L.; Abbott, L. R.; Adan, S. M. D.; Straatman, K. R.; Fry, A. M.; Hirota, K.; Tanaka, K.
10.1101/2023.09.08.556827 — cell biology — Posted on 2023-09-08
3637 Single Cell RNA-Seq Analysis of Regenerative Drug-Treated Human Pancreatic Islets Identifies A Cycling Alpha Cell Population As Key Beta Cell Progenitors
Karakose, E.; Wang, X.; Wang, P.; Carcamo, S.; Demircioglu, D.; Wood, O.; Kang, R.; Lambertini, L.; Lu, G.; Scott, D. K.; Garcia-Ocana, A.; Argmann, C.; Sebra, R.; Hasson, D.; Stewart, A. F.
10.1101/2023.09.07.556578 — cell biology — Posted on 2023-09-08
3651 Experimental testing of two urban stressors on freshwater biofilms
Vrba, R.; Lavoie, I.; Creusot, N.; Eon, M.; Millan-Navarro, D.; Feurtet-Mazel, A.; Mazzella, N.; Moreira, A.; Planas, D.; Morin, S.
10.1101/2023.06.11.544504 — ecology — Posted on 2023-09-08
3653 Dietary Pyruvate Targets Cytosolic Phospholipase A2 to Mitigate Inflammation and Obesity in Mice
Hasan, S.; Ghani, N.; Zhao, X.; Good, J.; Huang, A.; Wrona, H. L.; Liu, J.; Liu, C.
10.1101/2023.09.07.556702 — cell biology — Posted on 2023-09-08
3657 Chronic deregulation of the spindle assembly checkpoint triggers myelosuppression and gastrointestinal atrophy
Villunger, A.; Karbon, G.; Schuler, F.; Haschka, M.; Drach, M.; Sotillo, R.; Geley, S.; Spierings, D. C. J.; Tijhuis, A.; Foijer, F.
10.1101/2023.09.08.556836 — cell biology — Posted on 2023-09-08
3661 TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo
Kime, J.; Bose, D.; Arainga, M.; Haque, M. R.; Fennessey, C. M.; Caddell, R. A.; Thomas, Y.; Ferrell, D. E.; Ali, S.; Grody, E.; Goyal, Y.; Cicala, C.; Arthos, J.; Keele, B. F.; Vaccari, M.; Lorenzo-Redondo, R.; Hope, T. J.; Villinger, F. J.; Marinelli, E.
10.1101/2023.09.05.556422 — immunology — Posted on 2023-09-08
3662 KCNN4 links PIEZO-dependent mechanotransduction to NLRP3 inflammasome activation
Ran, L.; Ye, T.; Erbs, E.; Ehl, S.; Spassky, N.; Sumara, I.; Zhang, Z.; Ricci, R.
10.1101/2023.03.08.531717 — immunology — Posted on 2023-09-08
3665 Distinct subtypes of grey matter heterotopia show subtype-specific morpho-electric neuronal properties and dynamics of epileptiform activity in mice
Vermoyal, J.-C.; Hardy, D.; Goirand-Lopez, L.; Vinck, A.; Silvagnoli, L.; Fortoul, A.; Francis, F.; Cappello, S.; Bureau, I.; Represa, A.; Cardoso, C.; Watrin, F.; Marissal, T.; Manent, J.-B.
10.1101/2023.06.06.543853 — neuroscience — Posted on 2023-09-08
3666 Evaluation of surface-based hippocampal registration using ground-truth subfield definitions
DeKraker, J.; Palomero-Gallagher, N.; Kedo, O.; Ladbon-Bernasconi, N.; Muenzing, S. E. A.; Axer, M.; Amunts, K.; Khan, A. R.; Bernhardt, B.; Evans, A. C.
10.1101/2023.03.30.534978 — neuroscience — Posted on 2023-09-08
3667 BunDLe-Net: Neuronal Manifold Learning Meets Behaviour
Kumar, A.; Gilra, A.; Gonzalez-Soto, M.; Meunier, A.; Grosse-Wentrup, M.
10.1101/2023.08.08.551978 — neuroscience — Posted on 2023-09-08
3669 GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation
Grimm, F.; Asuaje, A.; Jain, A.; Silva dos Santos, M.; Kleinjung, J.; Nunes, P. M.; Gehrig, S.; Fets, L.; MacRae, J.; Anastasiou, D.
10.1101/2023.09.06.556522 — cancer biology — Posted on 2023-09-08
3670 Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer
Dondi, A.; Lischetti, U.; Jacob, F.; Singer, F.; Borgsmueller, N.; Coelho, R.; Tumor Profiler Consortium, ; Heinzelmann-Schwarz, V.; Beisel, C.; Beerenwinkel, N.
10.1101/2022.12.12.520051 — cancer biology — Posted on 2023-09-08
3671 Geometry-driven migration efficiency of autonomous epithelial cell clusters
Vercruysse, E.; Brückner, D. B.; Gomez-Gonzalez, M.; Luciano, M.; Kalukula, Y.; Rossetti, L.; Trepat, X.; Hannezo, E.; GABRIELE, S.
10.1101/2022.07.17.500364 — biophysics — Posted on 2023-09-08
3675 Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning
Laubscher, E.; Wang, X.; Razin, N.; Dougherty, T.; Xu, R.; Ombelets, L.; Pao, E.; Moffitt, J.; Yue, Y.; Van Valen, D. A.
10.1101/2023.09.03.556122 — bioinformatics — Posted on 2023-09-08
3678 Copper-independent lysosomal localization of the Wilson disease protein ATP7B
Maji, S.; Pirozzi, M.; Ruturaj, R.; Pandey, R.; Das, S.; Ghosh, T.; Gupta, A.
10.1101/2022.10.30.514457 — cell biology — Posted on 2023-09-08
3680 ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota
Cheng, M.-y.; Xu, B.; Sun, Y.; Wang, J.; Lu, Y.; Shi, C.; Pan, T.; Zhao, W.; Li, X.; Song, X.; Wang, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Zeng, Y.; Yang, D.; Wang, C.; Cao, X.
10.1101/2023.07.30.551192 — immunology — Posted on 2023-09-08
3681 Functional Organization of Glycolytic Metabolon on Mitochondria
Wang, H.; Vant, J.; Wu, Y.; Sanchez, R.; Micou, M. L.; Zhang, A.; Luczak, V.; Yu, S. B.; Jabbo, M.; Yoon, S.; Abushawish, A. A.; Ghassemian, M.; Griffis, E.; Hammarlund, M.; Singharoy, A.; Pekkurnaz, G.
10.1101/2023.08.26.554955 — neuroscience — Posted on 2023-09-08
3685 Endothelial-secreted Endocan protein acts as a PDGFR alpha ligand and regulates vascularity, radioresistance, and regional phenotype in glioblastoma
Bastola, S.; Pavlyukov, M. S.; Ghochani, Y.; Sharma, N.; Nakano, M. A.; Muthukrishnan, D.; Yu, S. Y.; Kim, M. S.; Sohrabi, A.; Biscola, N. P.; Yamashita, D.; Anufrieva, K.; Kawaguchi, R.; Qin, Y.; Seidlits, S. K.; Burlingame, A.; Oses-Prieto, J. A.; Havton, L. A.; Goldman, S.; Hjelmeland, A.; Nakano, I.; Kornblum, H.
10.1101/2020.10.12.335091 — cancer biology — Posted on 2023-09-08
3687 Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells
Calandrelli, R.; Wen, X.; Charles Richard, J. L.; Luo, Z.; Nguyen, T. C.; Chen, C.-J.; Qi, Z.; Xue, S.; Chen, W.; Yan, Z.; Wu, W.; Zaleta-Rivera, K.; Hu, R.; Yu, M.; Wang, Y.; Li, W.; Ma, J.; Ren, B.; Zhong, S.
10.1101/2021.06.10.447969 — genomics — Posted on 2023-09-08
3690 Cell wall fluidization by mechano-endopeptidases sets up a turgor-mediated volumetric pacemaker
Mukherjee, A.; Huang, Y.; Oh, S.; Sanchez, C.; Chang, Y.-F.; Liu, X.; Bradshaw, G. A.; Benites, N. C.; Paulsson, J.; Kirschner, M. W.; Sung, Y.; Elgeti, J.; Basan, M.
10.1101/2023.08.31.555748 — microbiology — Posted on 2023-09-08
3691 Plasticity of growth laws tunes resource allocation strategies in bacteria
Mukherjee, A.; Chang, Y.-F.; Huang, Y.; Ealy, J.; Polk, M.; Basan, M.
10.1101/2023.08.22.554312 — microbiology — Posted on 2023-09-08
3694 Differential modulation of cellular phenotype and drug sensitivity by extracellular matrix proteins in primary and metastatic pancreatic cancer cells
Usman, O. H.; Kumar, S.; Walker, R. R.; Xie, G.; Sumajit, H.; Jalil, A. R.; Ramakrishnan, S.; Dooling, L. J.; Wang, Y. J.; Irianto, J.
10.1101/2022.11.11.516201 — cancer biology — Posted on 2023-09-08
3695 Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma.
Makielski, K. M.; Sarver, A. L.; Henson, M. S.; Stuebner, K. M.; Borgatti, A.; Suksanpaisan, L.; Preusser, C.; Tabaran, A.-F.; Cornax, I.; O'Sullivan, M. G.; Chehadeh, A.; Groschen, D.; Bergsrud, K.; Pracht, S.; Winter, A.; Mills, L. J.; Schwabenlander, M. D.; Wolfe, M.; Farrar, M. A.; Cutter, G. R.; Koopmeiners, J. S.; Russell, S. J.; Modiano, J. F.; Naik, S.
10.1101/2023.04.16.533664 — cancer biology — Posted on 2023-09-08
3698 Lis1 binding regulates force-induced detachment of cytoplasmic dynein from microtubules
Kusakci, E.; Htet, Z. M.; Zhao, Y.; Gillies, J. P.; Reck-Peterson, S. L.; Yildiz, A.
10.1101/2022.06.02.494578 — biophysics — Posted on 2023-09-08
3699 Functional annotation of a divergent genome using sequence and structure-based homology.
Svedberg, D.; Winiger, R. R.; Berg, A.; Sharma, H.; Tellgren-Roth, C.; Debrunner-Vossbrinck, B. A.; Vossbrinck, C. R.; Barandun, J.
10.1101/2023.08.27.554996 — genomics — Posted on 2023-09-08
3700 Single molecule long-read real-time amplicon-based sequencing of CYP2D6: a proof-of-concept with hybrid haplotypes
Dong, R.; Thamilselvan, M.; Foo, J. C.; DeJarnette, J.; Hu, X.; Carvalho Henriques, B.; Wang, Y.; Wallace, K.; Sivapalan, S.; Buchner, A.; Yavorskyy, V.; Martens, K.; Maier, W.; Henigsberg, N.; Hauser, J.; Cattaneo, A.; Mors, O.; Rietschel, M.; Pfeffer, G.; Aitchison, K. J.
10.1101/2022.08.17.503990 — genomics — Posted on 2023-09-08
3702 Genomic and ecological factors shaping specialism and generalism across an entire subphylum
Opulente, D. A.; LaBella, A. L.; Harrison, M.-C.; Wolters, J. F.; Liu, C.; Li, Y.; Kominek, J.; Steenwyk, J. L.; Stoneman, H. R.; VanDenAvond, J.; Miller, C. R.; Langdon, Q. K.; Silva, M.; Goncalves, C.; Ubbelohde, E. J.; Li, Y.; Buh, K. V.; Jarzyna, M.; Haase, M. A. B.; Rosa, C. A.; Cadez, N.; Libkind, D.; DeVirgilio, J. H.; Hulfachor, A. B.; Kurtzman, C. P.; Sampaio, J. P.; Goncalves, P.; Zhou, X.; Shen, X.-X.; Groenewald, M.; Rokas, A.; Hittinger, C. T.
10.1101/2023.06.19.545611 — evolutionary biology — Posted on 2023-09-08
3703 Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons
Jones, A. G.; Schaal, G.; Boye, A.; Creemers, M.; Derolez, V.; Desroy, N.; Fiandrino, A.; Mouton, T. L.; Simier, M.; Smith, N.; Ouisse, V.
10.1101/2022.08.18.504439 — ecology — Posted on 2023-09-08
3705 Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis
Li, J. J.; Xin, N.; Yang, C.; Tavizon, L. A.; Hong, R.; Moore, T. I.; Tharyan, R. G.; Antebi, A.; Kim, H.-E.
10.1101/2023.09.07.556674 — cell biology — Posted on 2023-09-08
3706 CD36-Pyruvate Kinase M2 Signaling Promotes Macrophage Phagocytosis Through Mitochondrial Reactive Oxygen Species
Zhang, J.; Chang, J.; Zhao, Y.; Beg, M. A.; Huang, W.; Vick, L.; Zhang, H.; Gupta, A.; Castleberry, M.; Zhang, Z.; Dai, W.; Zhu, J.; Yang, M.; Brown, A. K.; Xu, Z.; Ma, Y.-q.; Smith, B. C.; Zielonka, J.; Cui, W.; Zheng, Z.; Chen, Y.
10.1101/2023.09.07.556574 — immunology — Posted on 2023-09-08
3710 Speciation in kleptoparasites of oak gall wasps often correlates with shifts into new tree habitats, tree organs, and gall morphospace
Ward, A.; Zhang, Y. M.; Brown, G. E.; Hippee, A. C.; Prior, K. M.; Rollins, S.; Sierra, N.; Sheikh, S. I.; Tribull, C. M.; Forbes, A. A.
10.1101/2023.09.07.556376 — evolutionary biology — Posted on 2023-09-07
3711 Effects of forest urbanization on the interplay between small mammal communities and their gut microbiota
Bouilloud, M.; Galan, M.; Pradel, J.; Loiseau, A.; FERRERO, J.; Gallet, R.; Roche, B.; Charbonnel, N.
10.1101/2023.09.07.556680 — ecology — Posted on 2023-09-07
3712 KSHV Terminal Repeat Regulates Inducible Lytic Gene Promoters
Izumiya, Y.; Algalil, A.; Espera, J. M.; Miura, H.; Inagaki, T.; Izumiya, C.; Kumar, A.
10.1101/2023.09.07.556745 — microbiology — Posted on 2023-09-07
3714 Early onset motor defects and electrographic seizures in a mouse model of the most common mutation in EEF1A2 related neurodevelopmental disorder, E122K
Marshall, G. F.; Fasol, M.; Davies, F. C. J.; Le Seelleur, M.; Alvarez, A. F.; Bennett-Ness, C.; Gonzalez Sulser, A.; Abbott, C. M.
10.1101/2023.09.07.556644 — neuroscience — Posted on 2023-09-07
3718 Precise manipulation of site and stoichiometry of capsid modification enables optimization of functional adeno-associated virus conjugates
Erickson, S. B.; Pham, Q.; Cao, X.; Glicksman, J.; Kelemen, R. E.; Shahraeini, S. S.; Bodkin, S.; Kiyam, Z.; Chatterjee, A.
10.1101/2023.09.07.556719 — synthetic biology — Posted on 2023-09-07
3720 Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: structural basis of their function
Klima, M.; Dejmek, M.; Duchoslav, V.; Eisenreichova, A.; Sala, M.; Chalupsky, K.; Chalupska, D.; Novotna, B.; Birkus, G.; Nencka, R.; Boura, E.
10.1101/2023.09.07.556653 — molecular biology — Posted on 2023-09-07
3721 Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation
Stolper, R. J.; Tsang, F. H.; Georgiades, E.; Hanssen, L. L.; Downes, D. J.; Harrold, C. L.; Hughes, J. R.; Beagrie, R. A.; Davies, B.; Kassouf, M.; Higgs, D.
10.1101/2023.09.07.556660 — molecular biology — Posted on 2023-09-07
3724 SARS-CoV-2 ORF7a mutation found in BF.5 and BF.7 sublineages impacts its functions
Timilsina, U.; Duffy, S.; Plianchaisuk, A.; Ito, J.; Sato, K.; Stavrou, S.
10.1101/2023.09.06.556547 — microbiology — Posted on 2023-09-07
3725 Alfalfa vein mottling virus, a novel potyvirid infecting Medicago sativa L.
Nemchinov, L. G.; Postnikova, O. A.; Wintermantel, W. M.; Palumbo, J. C.; Grinstead, S.
10.1101/2023.09.07.556681 — microbiology — Posted on 2023-09-07
3726 Transposon sequencing reveals the essential gene set and genes enabling gut symbiosis in the insect symbiont Caballeronia insecticola
Jouan, R.; Lextrait, G.; Lachat, J.; Yokota, A.; Cossard, R.; Naquin, D.; Timtchenko, T.; Kikuchi, Y.; Ohbayashi, T.; Mergaert, P.
10.1101/2023.09.07.556630 — microbiology — Posted on 2023-09-07
3728 Transmissibility, infectivity, and immune resistance of the SARS-CoV-2 BA.2.86 variant
Uriu, K.; Ito, J.; Kosugi, Y.; Tanaka, Y. L.; Mugita, Y.; Guo, Z.; Hinay, A. A.; Putri, O.; Kim, Y.; Shimizu, R.; Begum, M. M.; Jonathan, M.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Saito, A.; Ikeda, T.; Sato, K.
10.1101/2023.09.07.556636 — microbiology — Posted on 2023-09-07
3729 Ecophysiological and genomic approaches to cyanobacterial hardening for soil restoration
Roncero-Ramos, B.; Savaglia, V.; Durieu, B.; Van de Vrecken, I.; Richel, A.; Wilmotte, A.
10.1101/2023.09.07.556661 — microbiology — Posted on 2023-09-07
3731 Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2
Gracias, S.; Chazal, M.; Decombe, A.; Unterfinger, Y.; Sogues, A.; Pruvost, L.; Robert, V.; Lacour, S.; Lemasson, M.; Sourisseau, M.; Li, Z.; Richardson, J.; Decroly, E.; Pellegrini, S.; Caval, V.; Jouvenet, N.
10.1101/2023.09.07.556670 — microbiology — Posted on 2023-09-07
3732 Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection
Dremel, S. E.; Tagawa, T.; Koparde, V. N.; Arbuckle, J. H.; Kristie, T. M.; Krug, L. T.; Ziegelbauer, J. M.
10.1101/2023.09.07.556698 — microbiology — Posted on 2023-09-07
3736 The molecular reach of antibodies determines their SARS-CoV-2 neutralisation potency
Huhn, A.; Nissley, D. A.; Wilson, D. B.; Kutuzov, M. A.; Donat, R.; Tan, T. K.; Zhang, Y.; Barton, M. I.; Liu, C.; Dejnirattisai, W.; Supasa, P.; Mongkolsapaya, J.; Townsend, A.; James, W. S.; Screaton, G.; van der Merwe, P. A.; Deane, C.; Isaacson, S.; Dushek, O.
10.1101/2023.09.06.556503 — immunology — Posted on 2023-09-07
3737 Convergent Sequence Features of Antiviral B Cells
Abu-Shmais, A. A.; Vukovich, M. J.; Wasdin, P. T.; Suresh, Y. P.; Rush, S. A.; Gillespie, R. A.; Sankhala, R. S.; Choe, M.; Joyce, M. G.; Kanekiyo, M.; McLellan, J. S.; Georgiev, I. S.
10.1101/2023.09.06.556442 — immunology — Posted on 2023-09-07
3740 Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions
Jarc, L.; Bandral, M.; Zanfrini, E.; Lesche, M.; Kufrin, V.; Sendra, R.; Pezzolla, D.; Yiannios, I.; Khattak, S.; Neumann, K.; Ludwig, B.; Gavalas, A.
10.1101/2023.09.06.556505 — developmental biology — Posted on 2023-09-07
3741 CD9 marks myeloid/MegE-biased human hematopoiesis
Safi, F.; Dhapola, P.; Sommarin, M. N. E.; Karlsson, G.
10.1101/2023.09.06.556527 — cell biology — Posted on 2023-09-07
3742 Female baboon adrenal zona fasciculata and zona reticularis regulatory and functional proteins decrease across the life course
Huber, H. F.; Li, C.; Xie, D.; Gerow, K. G.; Register, T. C.; Shively, C. A.; Cox, L. A.; Nathanielsz, P. W.
10.1101/2023.09.06.556552 — physiology — Posted on 2023-09-07
3745 A study of genetic variants associated with skin traits in the Vietnamese population
Hoang, T. H.; Nguyen, H. X.; Vu, D. M.; Nguyen, T. H.; Pham, T. H.; Pham, T. D.; Can, T. T. T.; Nguyen, T. K.; Duong, V. C.; Vu, G. M.; Tran, M. H.; Nguyen, L. T. K.; Han, H. T. T.; Do, N. M.; Do, H. P.; Vo, N. S.
10.1101/2023.09.06.556474 — bioinformatics — Posted on 2023-09-07
3746 Knot or Not? Sequence-Based Identification of Knotted Proteins With Machine Learning
Sramkova, D.; Sikora, M.; Uchal, D.; Klimentova, E.; Perlinska, A. P.; Nguyen, M. L.; Korpacz, M.; Malinowska, R.; Rubach, P.; Simecek, P.; Sulkowska, J. I.
10.1101/2023.09.06.556468 — bioinformatics — Posted on 2023-09-07
3748 High Throughput Tomography (HiTT) on EMBL Beamline P14 on PETRA III
Albers, J.; Nikolova, M.; Svetlove, A.; Darif, N.; Lawson, M. J.; Schneider, T. R.; Schwab, Y.; Bourenkov, G.; Duke, E.
10.1101/2023.09.06.556509 — bioengineering — Posted on 2023-09-07
3750 Peanut Smut: A scientometric analysis for a pathosystem that concerns the Argentine peanut industry.
Cazon, L. I.; Paredes, J. A.; Miretti, E.; Gonzalez, N. R.; Suarez, L.; Conforto, E. C.; Rago, A. M.
10.1101/2023.09.06.555881 — plant biology — Posted on 2023-09-07
3756 Combinatorial circuit dynamics orchestrate flexible motor patterns in Drosophila
Shiozaki, H. M.; Wang, K.; Lillvis, J. L.; Xu, M.; Dickson, B. J.; Stern, D. L.
10.1101/2022.12.14.520499 — neuroscience — Posted on 2023-09-07
3759 Extensive genetic variation of leaf specialized metabolites in sessile oak (Quercus petraea) populations.
Coq--Etchegaray, D.; Bernillon, S.; Le Provost, G.; Kremer, A.; Ducousso, A.; Lalanne, C.; Bonne, F.; Moing, A.; Plomion, C.; Brachi, B.
10.1101/2023.04.07.536008 — evolutionary biology — Posted on 2023-09-07
3762 GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation
Anastasiou, D.; Grimm, F.; Asuaje, A.; Jain, A.; Silva dos Santos, M.; Kleinjung, J.; Nunes, P. M.; Gehrig, S.; Fets, L.; MacRae, J.
10.1101/2023.09.06.556522 — cancer biology — Posted on 2023-09-07
3765 Dynamics and quantitative contribution of the aminoglycoside 6'-N-acetyltransferase type Ib to amikacin resistance
d'Udekem d'Acoz, O.; Hue, F.; Ye, T.; Wang, L.; Leroux, M.; Rajngewerc, L.; Ramirez, M. S.; Reisner, W.; Tolmasky, M.; Reyes Lamothe, R.
10.1101/2023.09.05.556435 — microbiology — Posted on 2023-09-07
3767 TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo
Kime, J.; Bose, D.; Arainga, M.; Haque, M. R.; Fennessey, C. M.; Caddell, R. A.; Thomas, Y.; Ferrell, D. E.; Ali, S.; Grody, E.; Goyal, Y.; Cicala, C.; Arthos, J.; Keele, B. F.; Vaccari, M.; Lorenzo-Redondo, R.; Hope, T. J.; Villinger, F. J.; Marinelli, E.
10.1101/2023.09.05.556422 — immunology — Posted on 2023-09-07
3769 The glucocorticoid receptor as a master regulator of Müller cell gliosis in the diabetic retina
Pfaller, A. M.; Kaplan, L.; Carido, M.; Grassmann, F.; Diaz-Lezama, N.; Ghaseminejad, F.; Wunderlich, K.; Glänzer, S.; Pannicke, T.; Weber, B. H.; Koch, S.; Bonev, B.; Hauck, S. M.; Grosche, A.
10.1101/2023.09.06.556478 — neuroscience — Posted on 2023-09-07
3776 Stimulated Raman Photothermal Microscopy towards Ultrasensitive Chemical Imaging
Zhu, Y.; Ge, X.; Ni, H.; Yin, J.; Lin, H.; Wang, L.; Tan, Y.; Prabhu Dessai, C. V.; Li, Y.; Teng, X.; Cheng, J.-X.
10.1101/2023.03.06.531387 — bioengineering — Posted on 2023-09-07
3777 Reference genome of the endangered eastern quoll (Dasyurus viverrinus)
Hartley, G. A.; Frankenberg, S. R.; Robinson, N. M.; MacDonald, A. J.; Hamede, R. K.; Burridge, C. P.; Jones, M. E.; Faulkner, T.; Shute, H.; Brewster, R.; O'Neill, R. J.; Renfree, M. B.; Pask, A. J.; Feigin, C. Y.
10.1101/2023.09.06.556354 — genomics — Posted on 2023-09-07
3782 MAFB drives differentiation by permitting WT1 binding to podocyte 1 specific promoters
Massa, F. M.; Jian-Motamedi, F.; Serys, M.; Tison, A.; Loubat, A.; Lacas-Gervais, S.; Martin, L.; Belahbib, H.; Sarrazin, S.; Sieweke, M. H.; Schedl, A.
10.1101/2023.09.06.555670 — developmental biology — Posted on 2023-09-07
3785 Optimisation of cell fate determination for cultured muscle differentiation
Melzener, L.; Schaeken, L.; Fros, M.; Messmer, T.; Raina, D.; Kiessling, A.; van Haaften, T.; Spaans, S.; Dogan, A.; Post, M. J.; Flack, J. E.
10.1101/2023.09.06.556523 — cell biology — Posted on 2023-09-07
3787 Actin associates with actively elongating genes and binds directly to the Cdk9 subunit of P-TEFb
Kyheroinen, S.; Prajapati, B.; Sokolova, M.; Schmitz, M.; Geyer, M.; Vartiainen, M. K.
10.1101/2023.09.06.556538 — cell biology — Posted on 2023-09-07
3788 Replication stress in activated human NK cells induces sensitivity to apoptosis
Guilz, N. C.; Ahn, Y.-O.; Seo, S.; Fatima, H.; Pedroza, L. A.; SONI, R.; Wang, N.; Egli, D.; Mace, E.
10.1101/2023.09.07.556586 — immunology — Posted on 2023-09-07
3791 The Quest to Identify USP8 Inhibitors for Parkinsons Disease, a PAINful Experience.
Lang, S.; Bellany, F.; Lin, D.; Barrett, D. S.; Cartmill, K. R.; Fletcher, D. A.; Kerr, C.; Plater, A.; Forte, B.; Baragana, B.; Dixit, P.; Littleson, M. M.; Wheldon, M. C.; Gray, D. W.; Cunningham, F.
10.1101/2023.09.05.556294 — pharmacology and toxicology — Posted on 2023-09-07
3796 Myeloid A20 is critical for type-2 immune mediated helminth resistance
Petta, I.; Thorp, M.; Ciers, m.; Blancke, G.; Boon, L.; Meese, T.; Van Nieuwerburgh, F.; Wullaert, A.; Grencis, R. K.; Elewaut, D.; van Loo, G.; Vereecke, L.
10.1101/2023.09.05.556360 — immunology — Posted on 2023-09-07
3798 Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production.
Bao, B.; Wang, Y.; Boudreau, P.; Song, X.; Wu, M.; Chen, X.; Patik, I.; Tang, Y.; Ouahed, J. D.; Ringel, A.; Barends, J.; Wu, C.; Balskus, E. P.; Thiagarajah, J. R.; Liu, J.; Wessels, M. R.; Lencer, W. I.; Kasper, D. L.; An, D.; Horwitz, B. H.; Snapper, S.
10.1101/2023.09.05.555400 — immunology — Posted on 2023-09-07
3802 Trials and tribulations of Neotropical plant taxonomy: pace of tree species description
Lujan, M.; Lucas, E.; Michelangeli, F.; Prance, G.; Rzedowski, J.; Aguilar, D. S.; Serpell, E.; Sothers, C.; Zuntini, A.; Lemos, R. M.
10.1101/2023.09.05.556231 — plant biology — Posted on 2023-09-07
3803 Retrotransposon-driven environmental regulation of FLC leads to adaptive response to herbicide
Raingeval, M.; Leduque, B.; Baduel, P.; Edera, A.; Roux, F.; Colot, V.; Quadrana, L.
10.1101/2023.09.06.556499 — plant biology — Posted on 2023-09-07
3804 Vascular injury associated with ethanol intake is driven by AT1 receptor and mitochondrial dysfunction.
Awata, W. M. C.; Alves, J. V.; Costa, R. M.; Bruder-Nascimento, A.; Singh, S.; Barbosa, G. S.; Tirapelli, C. R.; Nascimento, T. B.
10.1101/2023.09.05.556341 — pharmacology and toxicology — Posted on 2023-09-07
3809 Chromosome-level genome assembly for the angiosperm Silene conica
Fields, P. D.; Weber, M. M.; Waneka, G.; Broz, A. K.; Sloan, D. B.
10.1101/2023.09.05.556365 — genomics — Posted on 2023-09-07
3811 Evolutionarily conserved ovarian fluid proteins are responsible for extending egg viability in salmonid fish
Gueho, A.; Zarski, D.; Rime, H.; Guevel, B.; Com, E.; Lavigne, R.; Nguyen, T.; Montfort, J.; Pineau, C.; Bobe, J.
10.1101/2023.09.05.556347 — evolutionary biology — Posted on 2023-09-07
3813 CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer
Gustafsson, K.; Rhee, C.; Frodermann, V.; Scadden, E. W.; Iwamoto, Y.; Palchaudhuri, R.; Hyzy, S. L.; Boitano, A. E.; Nahrendorf, M.; Scadden, D.
10.1101/2023.09.05.556397 — immunology — Posted on 2023-09-07
3814 Low albumin status accompanies multi-layered immunosuppressive phenotypes in metastatic breast cancer patients
Nakamura, Y.; Yoda, M.; Izumi, Y.; Kashima, Y.; Takahashi, M.; Nakatani, K.; Bamba, T.; He, C.; Konishi, R.; Saldajeno, D. P.; Vandenbon, A.; Suzuki, Y.; Toi, M.; Kawaguchi, K.; Kawaoka, S.
10.1101/2023.09.05.556440 — cancer biology — Posted on 2023-09-07
3817 Involvement of the splicing factor SART1 in the BRCA1-dependent homologous recombination repair of DNA double-strand breaks
Yamauchi, M.; Kato, R.; Yasuhara, T.; Uchihara, Y.; Hirakawa, M.; Ozaki, K.; Abe, Y.; Shibata, H.; Kawabata-Iwakawa, R.; Shakayeva, A.; Kot, P.; Miyagawa, K.; Suzuki, K.; Shibata, A.; Matsuda, N.
10.1101/2023.09.07.556638 — cell biology — Posted on 2023-09-07
3819 Distinct adrenal gland macrophages regulate corticosteroid production
O'Brien, C. J. O.; Sidarta-Oliveira, D.; Stawiarski, A.; Ratti, G.; Loyher, P.-L.; Makhlouf, M.; AbouMoussa, E. H.; Haberman, E.; Sweeney, C. A. P.; Mizuno, Y.; Ishii, T.; Hasegawa, T.; Gomez-Sanchez, E. P.; Gomez-Sanchez, C. E.; Gordon, S.; Greaves, D. R.; Saraiva, L. R.; Geissmann, F.; Domingos, A. I.
10.1101/2023.09.05.556330 — immunology — Posted on 2023-09-07
3822 Greening conceals evergreening: contrasting trends for a socio-ecological system in Arctic Europe
Tuomi, M. W.; Utsi, T. A.; Yoccoz, N.; Armstrong, C. W.; Gonzalez, V.; Hagen, S. B.; Jonsdottir, I. S.; Pugnaire, F. I.; Shea, K.; Wardle, D. A.; Zielosko, S.; Brathen, K. A.
10.1101/2022.02.28.482210 — ecology — Posted on 2023-09-07
3826 Social Context and Drug Cues Modulate Inhibitory Control in Cocaine Addiction: involvement of the STN evidenced through Functional Magnetic Resonance Imaging
Terenzi, D.; Simon, N.; Gachomba, M. J. M.; de Peretti, J. L.; Nazarian, B.; Sein, J.; Anton, J.-L.; Grandjean, D.; Baunez, C.; Chaminade, T.
10.1101/2023.09.06.556336 — neuroscience — Posted on 2023-09-07
3827 The demographic history of the wild crop relative Brachypodium distachyon is shaped by distinct past and present ecological niches.
Minadakis, N.; Williams, H.; Horvath, R.; Cakovic, D.; Stritt, C.; Thieme, M.; Bourgeois, Y. X. C.; Roulin, A.
10.1101/2023.06.01.543285 — ecology — Posted on 2023-09-07
3829 Optimization of chickpea irrigation in a semi-arid climate based on morpho-physiological parameters
Avneri, A.; Peleg, Z.; Bonfil, D.; Sadeh, R.; Perach, O.; Herrmann, I.; Abbo, S.; Lati, R.
10.1101/2023.02.12.528176 — plant biology — Posted on 2023-09-07
3830 Activator-blocker model of transcriptional regulation by pioneer-like factors
Riesle, A. J.; Gao, M.; Rosenblatt, M.; Hermes, J.; Hass, H.; Gebhard, A.; Veil, M.; Gruening, B.; Timmer, J.; Onichtchouk, D.
10.1101/2023.01.11.523615 — developmental biology — Posted on 2023-09-07
3831 A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in EHMT1
Urrutia, R. A.; Chi, Y.-I.; Jorge, S. D.; Jensen, D.; Smith, B. C.; Volkman, B.; Mathison, A.; Lomberk, G. A.; Zimmermann, M. T.
10.1101/2023.09.06.556558 — genomics — Posted on 2023-09-07
3834 Brain-wide human oscillatory LFP activity during visual working memory
Singh, B.; Wang, Z.; Madiah, L. M.; Gatti, S. E.; Fulton, J. N.; Johnson, G. W.; Rui, L.; Dawant, B. M.; Englot, D. J.; Bick, S. k.; Roberson, S. W.; Constantinidis, C.
10.1101/2023.09.06.556554 — neuroscience — Posted on 2023-09-07
3835 The spectral slope as a marker of excitation/inhibition ratio and cognitive functioning in multiple sclerosis
Akbarain, F.; Rossi, C.; Costers, L.; Dhooghe, M.; Dhaeseleer, M.; Nagels, G.; Van Schependom, J.
10.1101/2023.01.23.525139 — neuroscience — Posted on 2023-09-07
3836 Photoemission electron microscopy for connectomics
Boergens, K. M.; Wildenberg, G.; Li, R.; Lambert, L.; Moradi, A.; Stam, G.; Tromp, R.; van der Molen, S. J.; King, S. B.; Kasthuri, N.
10.1101/2023.09.05.556423 — neuroscience — Posted on 2023-09-06
3837 Humanoid robots are perceived as an evolutionary threat
Wei, Z.; Chen, Y.; Ren, J.; Piao, Y.; Zhang, P.; Zhao, Q.; Zha, R.; Qiu, B.; Zhang, D.; Bi, Y.; Han, S.; Li, C.; Zhang, X.
10.1101/2021.08.13.456053 — neuroscience — Posted on 2023-09-06
3838 Activin A targets extrasynaptic NMDA receptors to improve neuronal and behavioral deficits in a mouse model of Huntington disease
Nassrallah, W. B.; Ramandi, D.; Cheng, J.; Oh, J.; Mackay, J.; Sepers, M. D.; Lau, D.; Bading, H.; Raymond, L.
10.1101/2023.09.06.556580 — neuroscience — Posted on 2023-09-06
3840 Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS dependent apoptosis in ovarian cancer cells by targeting PAR-1
Nag, N.; Ray, T.; Tapader, R.; Gope, A.; Das, R.; Mahapatra, E.; Saha, S.; Pal, A.; Prasad, P.; Chatterjee, S.; Roy, S. S.; Pal, A.
10.1101/2023.09.06.556500 — cancer biology — Posted on 2023-09-06
3844 Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling
Nguyen, J.; Wang, L.; Lei, W.; Hu, Y.; Gulati, N.; Chavez-Madero, C.; Ahn, H.; Ginsberg, H. J.; Krawetz, R.; Brandt, M.; Betz, T.; Gilbert, P. M.
10.1101/2023.08.08.552533 — bioengineering — Posted on 2023-09-06
3848 Long-term changes in the timing of autumn migration in Alaska's boreal songbirds
Harding Scurr, A.; Hagelin, J.; Pendleton, G.; Dubour, K.; Blake, T.; Stuyck, C.; Allaby, E.
10.1101/2023.09.05.556417 — ecology — Posted on 2023-09-06
3849 A kinetic dichotomy between mitochondrial and nuclear gene expression drives OXPHOS biogenesis
McShane, E.; Couvillion, M.; Ietswaart, R.; Prakash, G.; Smalec, B. M.; Soto, I.; Baxter-Koenigs, A. R.; Choquet, K.; Churchman, L. S.
10.1101/2023.02.09.527880 — cell biology — Posted on 2023-09-06
3850 The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells
Gonzales, G. A.; Huang, S.; Rajwani, J.; Wilkinson, L.; Nguyen, J. A.; Wood, C. M.; Dinh, I.; Moore, M.; Cedeno, E.; Sikdar, S.; McKenna, N.; Ebacher, V.; Rosin, N. L.; Carneiro, M. B.; Surewaard, B.; Peters, N. C.; Biernaskie, J.; Mahoney, D. J.; Yates, R. M.; Canton, J.
10.1101/2023.08.11.553042 — cell biology — Posted on 2023-09-06
3852 Deep learning classification of ex vivo human colon tissues using spectroscopic OCT
Kendall, W.; Tian, Q.; Zhao, S.; Mirminachi, S.; Joseph, A.; Dufault, D.; Shi, C.; Roper, J.; Wax, A.
10.1101/2023.09.04.555974 — pathology — Posted on 2023-09-06
3853 GametesOmics: A Comprehensive Multi-Omics Database for Exploring the Gametogenesis in Humans and Mice
An, J.; Wang, J.; Kong, S.; Song, S.; Chen, W.; Yuan, P.; He, Q.; Chen, Y.; Li, Y.; Yang, Y.; Wang, W.; Li, R.; Yan, L.; Yan, Z.; Qiao, J.
10.1101/2023.09.05.556316 — bioinformatics — Posted on 2023-09-06
3855 Global metabolome changes induced by environnementaly relevant conditions in a marine-sourced Penicillium restrictum
Le, V.-T.; BERTRAND, S.; Brandolini Bunlon, M.; Gentil, E.; Robiou du Pont, T.; Rabesaotra, V.; Wielgosz Collin, G.; Mossion, A.; Grovel, O.
10.1101/2023.09.06.556477 — microbiology — Posted on 2023-09-06
3859 The catalytic mechanism of the RNA methyltransferase METTL3
Corbeski, I.; Vargas-Rosales, P. A.; Bedi, R. K.; Deng, J.; Coelho, D.; Braud, E.; Iannazzo, L.; Li, Y.; Huang, D.; Etheve-Quelquejeu, M.; Cui, Q.; Caflisch, A.
10.1101/2023.09.06.556513 — biochemistry — Posted on 2023-09-06
3860 Structural characterization of two nanobodies targeting the ligand-binding pocket of human Arc
Godoy Munoz, J. M.; Neset, L.; Markusson, S.; Weber, S.; Krokengen, O. C.; Sutinen, A.; Christakou, E.; Lopez Moreno, A. J.; Bramham, C.; Kursula, P.
10.1101/2023.09.06.556498 — biochemistry — Posted on 2023-09-06
3864 Cyclophilin D induces necrotic core formation by promoting mitochondria-mediated macrophage apoptosis in advanced atherosclerotic lesions
Koga, J.-i.; Umezu, R.; Shirouzu, T.; Kondo, Y.; Orkhonselenge, N.; Ueno, H.; Katsuki, S.; Matoba, T.; Nishimura, Y.; Kataoka, M.
10.1101/2023.09.05.556288 — molecular biology — Posted on 2023-09-06
3865 The characteristics of CTCF binding sequences contribute to enhancer blocking activity
Tsang, F. H.; Stolper, R. J.; Hanifi, M.; Cornell, L. J.; Francis, H. S.; Davies, B.; Higgs, D. R.; Kassouf, M. T.
10.1101/2023.09.06.556325 — molecular biology — Posted on 2023-09-06
3866 Lysine tRNA fragments and miR-194-5p co-regulate hepatic steatosis via beta-Klotho and Perilipin 2
Tzur, Y.; Winek, K.; Madrer, N.; Dubnov, S.; Bennett, E. R.; Greenberg, D. S.; Hanin, G.; Gammal, A.; Tam, J.; Arkin, I. T.; Paldor, I.; Soreq, H.
10.1101/2023.09.06.556514 — molecular biology — Posted on 2023-09-06
3867 High-throughput, microscopy-based screening, and quantification of genetic elements
Zhang, R.; Huang, Y.; Li, M.; Wang, L.; Li, B.; Xia, A.; Li, Y.; Yang, S.; JIN, F.
10.1101/2023.09.06.556327 — molecular biology — Posted on 2023-09-06
3870 Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens
Schlabach, M. R.; Lin, S.; Collester, Z.; Wrockage, C.; Shenker, S.; Calnan, C.; Xu, T.; Gannon, H.; Williams, L.; Thompson, F.; Dunbar, P.; LaMothe, R.; Garrett, T. E.; Colletti, N.; Hohmann, A.; Tubo, N.; Bullock, C.; Le Mercier, I.; Sofjan, K.; Merkin, J. J.; Keegan, S.; Kryokov, G. V.; Dugopolski, C.; Stegmeier, F.; Wong, K.; Sharp, F. A.; Cadzow, L.; Benson, M. J.
10.1101/2023.09.05.555798 — immunology — Posted on 2023-09-06
3871 High resolution longitudinal molecular and morphological tracking of planktonic threats to salmon aquaculture.
Alguero-Muniz, M.; Spatharis, S.; Dwyer, T.; de Noia, M.; Cheaib, B.; Robertson, B.; Johnstone, C.; Welsh, J.; Macphee, A.; Mazurkiewicz, M.; Bickerdike, R.; Migaud, H.; McGhee, C.; Praebel, K.; Llewellyn, M. S.
10.1101/2023.09.04.556215 — zoology — Posted on 2023-09-06
3873 Distilling Mechanistic Models From Multi-Omics Data
Erwin, S.; Fletcher, J. R.; Sweeney, D. C.; Theriot, C. M.; Lanzas, C.
10.1101/2023.09.06.556597 — systems biology — Posted on 2023-09-06
3877 Abca4 inhibition in a cone-rich rodent leads to Stargardt Disease type 1-like retinal degeneration
Sassone, F.; Ciocca, D.; Roux, M. J.; Rossolillo, P.; Birling, M.-C.; Sparrow, J. R.; Hicks, D.
10.1101/2023.09.04.556201 — pathology — Posted on 2023-09-06
3879 CATHI: An interactive platform for comparative genomics and homolog identification
Becker, L.; Spohr, P.; Klau, G. W.; Axmann, I. M.; Fraune, S.; Schmelling, N. M.
10.1101/2023.09.04.556229 — bioinformatics — Posted on 2023-09-06
3882 Deep learning enables accurate soft tissue deformation estimation in vivo
Huff, R. D.; Houghton, F.; Earl, C. C.; Ghajar-Rahimi, E.; Dogra, I.; Yu, D.; Harris-Adamson, C.; Goergen, C. J.; O'Connell, G. D.
10.1101/2023.09.04.556266 — bioengineering — Posted on 2023-09-06
3883 Cas9 is mostly orthogonal to human systems of DNA break sensing and repair
Maltseva, E. A.; Vasil'eva, I. A.; Moor, N. A.; Kim, D. V.; Dyrkheeva, N. S.; Kutuzov, M. M.; Vokhtantsev, I. P.; Kulishova, L. M.; Zharkov, D. O.; Lavrik, O. I.
10.1101/2023.09.05.556296 — biochemistry — Posted on 2023-09-06
3885 The structure of a C. neoformans polysaccharide motif recognized by protective antibodies: a combined NMR and MD study
Hargett, A. A.; Azurmendi, H. F.; Crawford, C. J.; Wear, M. P.; Oscarson, S.; Casadevall, A. A.; Freedberg, D. I.
10.1101/2023.09.06.556507 — biochemistry — Posted on 2023-09-06
3887 Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic disease.
Charlton, P.; O'Reilly, D.; Philippou, Y.; Rao, S. R.; Lamb, A. D.; Mills, I. G.; Higgins, G.; Hamdy, F. C.; Verrill, C.; Buffa, F. M.; Bryant, R. J.
10.1101/2023.09.04.555868 — genomics — Posted on 2023-09-06
3889 Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohns disease
Humphreys, D. T.; Lewis, A.; Pan-Castillo, B.; Berti, G.; Mein, C. A.; Wozniak, E.; Gordon, H.; Gadhok, R.; Minicozzi, A.; Chinaleong, J.; Feakins, R.; Giannoulatou, E.; James, L. K.; Stagg, A.; Lindsay, J. O.; Silver, A.
10.1101/2023.09.04.556163 — genomics — Posted on 2023-09-06
3891 Genetic basis and evolution of structural color polymorphism in an Australian songbird
Sin, S. Y. W.; Ke, F.; Chen, G.; Huang, P.-Y.; Enbody, E.; Karubian, J.; Webster, M.; Edwards, S. V.
10.1101/2023.09.03.556140 — evolutionary biology — Posted on 2023-09-06
3892 An experimental approach towards untangling the role of nature versus nurture in shaping the microbiome of social insects
Cohen, T. M.; Bodner, L.; Turjeman, S.; Sharon, E.; Cohen, A.; Bouchebti, S.; Tikhonov, E.; Koren, O.; Levin, E.
10.1101/2023.09.04.556269 — evolutionary biology — Posted on 2023-09-06
3893 Schizosaccharomyces versatilis represents a distinct evolutionary lineage.
Etherington, G. J.; Nieduszynski, C.; Oliferenko, S.; Gomez Gil, E.; Haerty, W.
10.1101/2023.09.04.556188 — evolutionary biology — Posted on 2023-09-06
3895 Abundance of Northern Hemisphere tree species declines in the warm and arid regions of their climatic niches
Astigarraga, J.; Esquivel-Muelbert, A.; Ruiz-Benito, P.; Rodriguez-Sanchez, F.; Zavala, M. A.; Vila-Cabrera, A.; Schelhaas, M.-J.; Kunstler, G.; Woodall, C. W.; Cienciala, E.; Dahlgren, J.; Govaere, L.; Konig, L. A.; Lehtonen, A.; Talarczyk, A.; Pugh, T. A. M.
10.1101/2023.09.04.556202 — ecology — Posted on 2023-09-06
3896 Reservoir ecosystems support large pools of fish biomass
Parisek, C. A.; De Castro, F. A.; Colby, J. D.; Leidy, G. R.; Sadro, S.; Rypel, A. L.
10.1101/2023.09.04.556263 — ecology — Posted on 2023-09-06
3899 Emergence of disease specific endothelial and stromal cell populations involved in arterial remodeling during development of pulmonary arterial hypertension
Cober, N. D.; McCourt, E.; Soares Godoy, R.; Deng, Y.; Schlosser, K.; Situ, A.; Cook, D. P.; Lemay, S.-E.; Klouda, T.; Yuan, K.; Bonnet, S.; Stewart, D. J.
10.1101/2023.09.06.555321 — molecular biology — Posted on 2023-09-06
3901 Oral immunization of goats and foxes with a recombinant NDV vectored rabies vaccine
Murr, M.; Freuling, C.; Perez-Bravo, D.; Grund, C.; Mettenleiter, T. C.; Römer-Oberdörfer, A.; Müller, T.; Finke, S.
10.1101/2023.09.06.556473 — microbiology — Posted on 2023-09-06
3903 Episymbiotic bacterium induces intracellular lipid droplet production in its host bacteria
Dong, P.-T.; Tian, J.; Kobayashi-Kirschvink, K. J.; Cen, L.; McLean, J. S.; Bor, B.; Shi, W.; He, X.
10.1101/2023.09.06.556576 — microbiology — Posted on 2023-09-06
3904 Dynamics of associated microbiomes during algal bloom development: to see and to be seeing
Meirkhanova, A.; Zhumakhanova, A.; Len, P.; Schoenbach, C.; Levi, E. E.; Jeppesen, E.; Davidson, T. A.; Barteneva, N. S.
10.1101/2023.09.05.556447 — microbiology — Posted on 2023-09-06
3905 Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels
Conceicao-Neto, N.; Pierson, W.; Vacca, M.; Beyens, M.; De Clerck, B.; Aerts, L.; Voeten, B.; De Pooter, D.; Verschueren, L.; Dockx, K.; Vandenberk, M.; De Troyer, E.; Verwilt, K.; Van Hove, C.; Verslegers, M.; Bosseler, L.; Crabbe, M.; Krishna, V.; Najera, I.; Van Gulck, E.
10.1101/2023.09.04.556204 — immunology — Posted on 2023-09-06
3908 The immunoglobulin A isotype of the Arabian camel (Camelus dromedarius) preserves the dualistic structure of unconventional single-domain and canonical heavy chains
Conca, W.; Salih, S.; Al-Rabiah, R.; Parhar, R.; Abd-Elnaeim, M.; Al-Hindas, H.; Tinson, A.; Collison, K.; Kishore, U.; Al-Mohanna, F.
10.1101/2023.09.04.556198 — immunology — Posted on 2023-09-06
3911 Anatomical Modeling and Optimization of Speckle Contrast Optical Tomography
Lin, C.-H. P.; Orukari, I.; Frisk, L. C.; Verma, M.; Chetia, S.; Beslija, F.; Eggebrecht, A. T.; Durduran, T.; Culver, J. P.; Trobaugh, J. W.
10.1101/2023.09.06.556565 — neuroscience — Posted on 2023-09-06
3913 Thymoquinone-Protoflavone Hybrid Molecules as Potential Antitumor Agents
Sara, A. H. H.; Tayeb, B. A.; Gonda, T.; Girst, G.; Szori, K.; Berkecz, R.; Zupko, I.; Minorics, R.; Hunyadi, A.
10.1101/2023.09.04.555971 — pharmacology and toxicology — Posted on 2023-09-06
3915 Flexible Methods for Standard Error Calculation in digital PCR Experiments
Chen, Y.; De Spiegelaere, W.; Trypsteen, W.; Gleerup, D.; Vandesompele, J.; Thas, O.
10.1101/2023.09.06.556592 — bioinformatics — Posted on 2023-09-06
3917 Formin tails act as a switch, inhibiting or enhancing processive actin elongation
Bremer, K.; Wu, C.; Patel, A.; He, K.; Grunfeld, A.; Chanfreau, G.; Quinlan, M. E.
10.1101/2023.09.06.556579 — biochemistry — Posted on 2023-09-06
3918 Intragroup sociality drives individual participation in intergroup competition in an urban-dwelling nonhuman primate
Chakraborty, B.; Kaburu, S. S. K.; Balasubramaniam, K. N.; Marty, P. R.; Beisner, B.; Bliss-Moreau, E.; Mohan, L.; Rattan, S. K.; McCowan, B.
10.1101/2023.09.06.556573 — animal behavior and cognition — Posted on 2023-09-06
3919 The genome and population genomics of allopolyploid Coffea arabica reveal the diversification history of modern coffee cultivars
Salojarvi, J.; Rambani, A.; Yu, Z.; Guyot, R.; Strickler, S.; Lepelley, M.; Wang, C.; Rajaraman, S.; Rastas, P.; Zheng, C.; Munoz, D. S.; Meidanis, J.; Paschoal, A. R.; Bawin, Y.; Krabbenhoft, T.; Wang, Z. Q.; Fleck, S.; Aussel, R.; Bellanger, L.; Charpagne, A.; Fournier, C.; Kassam, M.; Lefebvre, G.; Metairon, S.; Moine, D.; Rigoreau, M.; Stolte, J.; Hamon, P.; Couturon, E.; Tranchant-Dubreuil, C.; Mukherjee, M.; Lan, T.; Engelhardt, J.; Stadler, P.; DeLemos, S. C.; Suzuki, S. I.; Sumirat, U.; ChingMan, W.; Dauchot, N.; Orozco-Arias, S.; Garavito, A.; Kiwuka, C.; Musoli, P.; Nalukenge, A.; Gu
10.1101/2023.09.06.556570 — genomics — Posted on 2023-09-06
3920 Systems genetics analysis of human body fat distribution genes identifies Wnt signaling and mitochondrial activity in adipocytes
Reed, J. N.; Huang, J.; Li, Y.; Ma, L.; Banka, D.; Wabitsch, M.; Wang, T.; Ding, W.; Bjorkegren, J. L. M.; Civelek, M.
10.1101/2023.09.06.556534 — systems biology — Posted on 2023-09-06
3921 Automated detection and classification of polioviruses from nanopore sequencing reads using piranha
O'Toole, A. N.; Colquhoun, R.; Ansley, C.; Troman, C.; Maloney, D.; Vance, Z.; Akello, J.; Bujaki, E.; Majumdar, M.; Khurshid, A.; Arshad, Y.; Alam, M. M.; Martin, J.; Shaw, A. G.; Grassly, N. C.
10.1101/2023.09.05.556319 — bioinformatics — Posted on 2023-09-06
3922 Ghost W chromosomes and unique genome architecture in ghost moths of the family Hepialidae
Chung Volenikova, A.; Sahara, K.; Stundlova, J.; Dalikova, M.; Koutecky, P.; Grof-Tisza, P.; Simonsen, T. J.; Zurovec, M.; Provaznikova, I.; Walters, J. R.; Marec, F.; Nguyen, P.
10.1101/2023.09.03.556148 — genomics — Posted on 2023-09-06
3925 Nifuroxazide enhances radiotherapy efficacy against hepatocellular carcinoma by upregulating PD-L1 degradation via the ubiquitin-proteasome pathway
Zhao, T.; Wei, P.; Zhang, C.; Zhou, S.; Guo, S.; Cheng, S.; Gan, Z.; Xia, Y.; Zhang, Y.; Guo, S.; Zhong, J.; Yang, Z.; Tu, F.; Wang, Q.; Bai, J.; Ren, F.; Feng, Z.; Jia, H.
10.1101/2023.09.03.556121 — immunology — Posted on 2023-09-06
3930 CAR T cells recognizing CD276 and Dual-CAR T cells against CD276/FGFR4 promote rhabdomyosarcoma clearance in an orthotopic mouse model
Timpanaro, A.; Piccand, C.; Dzhumashev, D.; Anton-Joseph, S.; Moser, J.; Robbi, A.; Roessler, J.; Bernasconi, M.
10.1101/2023.09.05.555125 — cancer biology — Posted on 2023-09-06
3933 Evolutionary diversity of the control of the azole response by Tra1 across yeast species
Librais, G. M.; Jiang, Y.; Razzaq, I.; Brandl, C. J.; Shapiro, R. S.; Lajoie, P.
10.1101/2023.09.05.556458 — genetics — Posted on 2023-09-06
3934 Standardisation of cell-free DNA measurements: An International Study on Comparability of Low Concentration DNA Measurements using cancer variants
Burke, D.; Devonshire, A. S.; Pinheiro, L.; Jones, G.; Griffiths, K. R.; Fernandez-Gonzalez, A.; Forbes-Smith, M.; McLaughlin, J.; Emslie, K. R.; Weidner, C.; Mankertz, J.; Leguizamon Guerrero, J. E.; Medeiros, M. N. d.; Flatschart, R. B.; Saraiva, A. M.; Beltrao, P. J. I.; Divieto, C.; Revel, L.; Bae, Y.-K.; Dong, L.; Niu, C.; Wang, X.; Temisak, S.; Shibayama, S.; Yalcinkaya, B.; Akgoz, M.; Macdonald, R.; Plauth, A.; Huggett, J.
10.1101/2023.09.06.554514 — genetics — Posted on 2023-09-06
3936 Diving efficiency at depth and pre-breeding foraging effort increase with haemoglobin levels in gentoo penguins
McComb-Turbitt, S. P.; Crossin, G. T.; Tierney, M.; Brickle, P.; Trathan, P.; Williams, T.; Auger-Methe, M.
10.1101/2023.05.14.539907 — ecology — Posted on 2023-09-06
3938 Differing effects of alcohol use on epigenetic and brain age in adult children of alcoholic parents
Scholl, J. L.; Pearson, K.; Fercho, K. A.; Van Asselt, A. J.; Kallsen, N. A.; Ehli, E. A.; Potter, K. N.; Brown-Rice, K. A.; Forster, G. L.; Baugh, L. A.
10.1101/2023.09.05.556404 — neuroscience — Posted on 2023-09-06
3939 The brain's topographical organization shapes dynamic interaction patterns to support flexible behavior
Wang, X.; Krieger-Redwood, K.; Lyu, B.; Lowndes, R.; Wu, G.; Souter, N. E.; Wang, X.; Kong, R.; Shafiei, G.; Bernhardt, B.; Cui, Z.; Smallwood, J.; Du, Y.; Jefferies, E.
10.1101/2023.09.06.556465 — neuroscience — Posted on 2023-09-06
3940 Controlling focality and intensity of non-invasive deep brain stimulation using multipolar temporal interference in non-human primates and rodents
Botzanowski, B.; ACERBO, E.; lehmann, s.; Kearsley, S. L.; Steiner, M.; Neufeld, E.; MISSEY, F.; Muller, L.; Jirsa, V.; Corneil, B. D.; Williamson, A.
10.1101/2023.09.05.556444 — neuroscience — Posted on 2023-09-06
3941 Functional development of eye movements and visuomotor circuits in lampreys
Barandela, M.; Nunez-Gonzalez, C.; Suzuki, D. G.; Jimenez-Lopez, C.; Pombal, M. A.; Perez-Fernandez, J.
10.1101/2023.09.06.556551 — neuroscience — Posted on 2023-09-06
3943 Loss of Ezh2 in the medial ganglionic eminence alters interneuron fate, cell morphology and gene expression profiles
Rhodes, C. T.; Asokumar, D.; Sohn, M.; Naskar, S.; Elisha, L.; Stevenson, P.; Lee, D. R.; Zhang, Y.; Rocha, P. P.; Dale, R. K.; Lee, S.; Petros, T. J.
10.1101/2023.09.06.556544 — neuroscience — Posted on 2023-09-06
3946 Ancient mitogenomes reveal evidence for the late Miocene dispersal of mergansers to the Southern Hemisphere
Rawlence, N.; Verry, A.; Cole, T.; Shepherd, L.; Tennyson, A.; Williams, M.; Wood, J.; Mitchell, K.
10.1101/2023.09.03.556105 — genetics — Posted on 2023-09-06
3947 Whole mitogenome analysis highlights demographic history and shared connections among distal Indigenous groups of Mexico Complete mitogenome sequencing from 60 Mexican Native American groups
Flores-Huacuja, M.; Snow, M.; Ramos-Madrigal, J.; Contreras-Cubas, C.; Barajas-Olmos, F.; Gonzalez-Oliver, A.; Mendoza-Caamal, E.; Ciceron-Arellano, I.; Centeno-Cruz, F.; Cordova, E. J.; Baca, P.; Flores-Martinez, S. E.; Ortiz-Lopez, R.; Reynolds, A. W.; Kostic, A. D.; Villafan-Bernal, J. R.; Galaviz-Hernandez, C.; Garcia-Zapien, A. G.; Miranda-Ortiz, H.; Lazalde-Ramos, B. P.; Loeza-Becerra, F.; Carnevale, A.; Rangel-Villalobos, H.; Sosa-Macias, M.; Rojas-Martinez, A.; Martinez-Hernandez, A.; Garcia-Ortiz, H.; Orozco, L.
10.1101/2023.09.03.556146 — genetics — Posted on 2023-09-06
3951 Influenza A virus H1N1-derived circNP37 positively regulates viral replication by sponging host miR-361-5p
Chunyu, Z.; Jingyu, W.; Yalan, D.; Chunli, L.; Mengchan, H.; Yu, Z.; Ziaoqing, Z.; Yiwei, G.; Fangliang, Z.; Yuan, Z.; Chen, J.
10.1101/2023.09.04.556164 — microbiology — Posted on 2023-09-06
3953 CTCF regulates hepatitis B virus cccDNA chromatin topology
Dobrica, M. O.; Varghese, C. S.; Harris, J. M.; Ferguson, J.; Magri, A.; Arnold, R.; Varnai, C.; Parish, J. L.; McKeating, J. A.
10.1101/2023.09.06.556185 — microbiology — Posted on 2023-09-06
3956 Social Context and Drug Cues Modulate Inhibitory Control in Cocaine Addiction: involvement of the STN evidenced through Functional Magnetic Resonance Imaging
Terenzi, D.; Simon, N.; Gachomba, M. J. M.; de Peretti, J. L.; Nazarian, B.; Sein, J.; Anton, J.-L.; Grandjean, D.; Baunez, C.; Chaminade, T.
10.1101/2023.09.06.556336 — neuroscience — Posted on 2023-09-06
3957 A single-cell atlas of ABCA7 loss-of-function reveals lipid disruptions, mitochondrial dysfunction and DNA damage in neurons
von Maydell, D.; Wright, S.; Bonner, J. M.; Pao, J.; Menchaca, G. S.; Welch, G.; Boix, C. A.; Mathys, H.; Leclerc, G.; Leary, N.; Samaan, G.; Kellis, M.; Tsai, L.-H.
10.1101/2023.09.05.556135 — neuroscience — Posted on 2023-09-06
3959 Photoemission electron microscopy for connectomics
Boergens, K. M.; Wildenberg, G.; Li, R.; Lambert, L.; Moradi, A.; Stam, G.; Tromp, R.; van der Molen, S. J.; King, S. B.; Kasthuri, N.
10.1101/2023.09.05.556423 — neuroscience — Posted on 2023-09-06
3960 Kisspeptin cell-type and fiber projection analysis suggests its potential role in central sensorial processing and behavioral state control
Zhang, L.; Hernandez, V. S.; Zetter, M. A.; Hernandez-Gonzalez, R.; Hernandez-Perez, O. R.; Camacho-Arroyo, I.; Eiden, L. E.; Millar, R. P.
10.1101/2023.09.05.556375 — neuroscience — Posted on 2023-09-06
3961 Causal Genetic Loci for a Motivated Behavior Spectrum Harbor Psychiatric Risk Genes
Xu, J.; Casanave, R.; Chitre, A. S.; Wang, Q.; Nguyen, K.-M.; Blake, C.; Wagle, M.; Cheng, R.; Polesskaya, O.; Palmer, A. A.; Guo, S.
10.1101/2023.09.06.556529 — neuroscience — Posted on 2023-09-06
3962 Investigating task-free functional connectivity patterns in newborns using functional near-infrared spectroscopy
Vahidi, H.; Kowalczyk, A.; Stubbs, K.; Musabi, M.; Roychaudhuri, S.; Kent, M.; Bhattacharya, S.; De Ribaupierre, S.; St. Lawrence, K.; Mohsenzadeh, Y.; Duerden, E.
10.1101/2023.09.05.555980 — neuroscience — Posted on 2023-09-06
3964 The association between Dioscorea sansibarensis and Orrella dioscoreae as a model for hereditary leaf symbiosis
Acar, T.; Moreau, S.; Jardinaud, M.-F.; Houdinet, G.; Maviane-Macia, F.; De Meyer, F.; Hoste, B.; Leroux, O.; Coen, O.; Le Ru, A.; Peeters, N.; Carlier, A.
10.1101/2023.09.04.555865 — plant biology — Posted on 2023-09-06
3965 Enriched Single-Nucleus RNA-Sequencing reveals unique attributes of distal convoluted tubule cells
Su, X.-T.; Reyes, J. V.; Lackey, A. E.; Maeoka, Y.; Cornelius, R. J.; McCormick, J. A.; Yang, C.-L.; Jung, H. J.; Welling, P. A.; Nelson, J. W.; Ellison, D. H.
10.1101/2023.09.05.555810 — physiology — Posted on 2023-09-06
3967 Phosphoproteomics implicates glutamatergic and dopaminergic signalling in the antidepressant-like properties of the iron chelator deferiprone
Uzungil, V.; Luza, S.; Opazo, C. M.; Mees, I.; Li, S.; Ang, C.-S.; Williamson, N. A.; Bush, A. I.; Hannan, A. J.; Renoir, T.
10.1101/2023.09.06.556022 — bioinformatics — Posted on 2023-09-06
3969 FRET-based sensor for measuring adenine nucleotide binding to AMPK
Abi Nahed, R.; Pelosse, M.; Aulicino, F.; Cottaz, F.; Berger, I.; Schlattner, U.
10.1101/2023.09.05.553069 — biochemistry — Posted on 2023-09-06
3971 Serial dilution shapes genetic variation and defines conservation units in Asian elephants
Khan, A.; Sil, M.; Thekaekara, T.; Sinha, I.; Khurana, R.; Sukumar, R.; Ramakrishnan, U.
10.1101/2023.09.04.556173 — evolutionary biology — Posted on 2023-09-06
3972 Germ cells do not progress through spermatogenesis in the infertile zebrafish testis
Sposato, A. L.; Llewellyn, D. R.; Weber, J. M.; Hollins, H. L.; Schrock, M. N.; Farrell, J. A.; Gagnon, J. A.
10.1101/2023.09.05.556432 — developmental biology — Posted on 2023-09-06
3973 KLF7 is a general inducer of human pluripotency
Arboit, M.; Zorzan, I.; Pellegrini, M.; Martini, P.; Carbognin, E.; Martello, G.
10.1101/2023.09.06.556189 — developmental biology — Posted on 2023-09-06
3974 Repeated Plasmodium vivax blood stage infection provides sterile protection against homologous challenge in non-human primates
Obaldia, N.; da Silva Filho, J. L.; Nunez, M.; Glass, K.; Oulton, T.; Achcar, F.; Wirjanata, G.; Duraisingh, M.; Felgner, P.; Tetteh, K.; Bozdech, Z.; Otto, T.; Marti, M.
10.1101/2023.02.13.528262 — microbiology — Posted on 2023-09-06
3975 Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus.
Greigert, V.; Saraav, I.; Son, J.; Dayao, D.; Antia, A.; Tzipori, S.; Witola, W.; Stappenbeck, T. S.; Ding, S.; Sibley, L. D.
10.1101/2023.08.30.555581 — microbiology — Posted on 2023-09-06
3977 Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner.
Fazazi, M. R.; Doss, P. M. I. A.; Pereira, R.; Fudge, N.; Regmi, A.; Joly-Beauparlant, C.; Akbar, I.; Yeola, A. P.; Mailhot, B.; Baillargeon, J.; Grenier, P.; Bertrand, N.; Lacroix, S.; Droit, A.; Moore, C. S.; Rojas, O. L.; Rangachari, M.
10.1101/721696 — immunology — Posted on 2023-09-06
3981 Pathogen lifestyle determines host genetic signature of quantitative disease resistance in oilseed rape (Brassica napus)
Jacott, C. N.; Schoonbeek, H.-j.; Sidhu, G. S.; Steuernagel, B.; Kirby, R.; Zheng, X.; von Tiedermann, A.; Macioszek, V. K.; Kononowicz, A. K.; Fell, H.; Fitt, B. D. L.; Mitrousia, G. K.; Stotz, H. U.; Ridout, C. J.; Wells, R.
10.1101/2023.08.02.551671 — plant biology — Posted on 2023-09-06
3982 Single-Molecule Reaction-Diffusion
Xu, L. W. Q.; Jazani, S.; Kilic, Z.; Presse, S.
10.1101/2023.09.05.556378 — biophysics — Posted on 2023-09-06
3985 Scalable bio-platform to recover critical metals fromcomplex waste sources
Good, N. M.; Kang-Yun, C. S.; Su, M. Z.; Zytnick, A. M.; Vu, H. N.; Grace, J. M.; Nguyen, H. H.; Park, D. M.; Skovran, E.; Fan, M.; Martinez-Gomez, N. C.
10.1101/2023.09.02.556034 — bioengineering — Posted on 2023-09-06
3986 The defensome of complex bacterial communities
Beavogui, A.; Lacroix, A.; Wiart, N.; Poulain, J.; Delmont, T. O.; Paoli, L.; Wincker, P.; Oliveira, P. H.
10.1101/2023.08.12.553040 — genomics — Posted on 2023-09-06
3987 A deeper cascade of mechanisms involved in cold resistance in Hevea brasiliensis
Silva, C. C.; Bajay, S. K.; Aono, A. H.; Francisco, F. R.; Junior, R. B.; de Souza, A. P.; Mantello, C. C.; Vicentini dos Santos, R.
10.1101/2021.11.02.466997 — genomics — Posted on 2023-09-06
3990 The slow evolving genome of the xenacoelomorph worm Xenoturbella bocki
Schiffer, P. H.; Natsidis, P.; Leite, D. J.; Robertson, H.; Lapraz, F.; Marletaz, F.; Fromm, B.; Baudry, L.; Simpson, F.; Hoye, E.; Zakrzewski, A.-C.; Kapli, P.; Hoff, K. J.; Mueller, S.; Marbouty, M.; Marlow, H.; Copley, R. H.; Koszul, R.; Sarkies, P.; Telford, M. J.
10.1101/2022.06.24.497508 — evolutionary biology — Posted on 2023-09-06
3991 Comparative phylogenomic analyses of SNP versus full locus datasets: insights and recommendations for researchers
Suissa, J. S.; De La Cerda, G. Y.; Graber, L. C.; Jelley, C.; Wickell, D.; Phillips, H. R.; Grinage, A. D.; Moreau, C. S.; Specht, C. D.; Doyle, J. J.; Landis, J. B.
10.1101/2023.09.02.556036 — evolutionary biology — Posted on 2023-09-06
3992 A short course of antibiotics selects for persistent resistance in the human gut
Yaffe, E.; Dethlefsen, L.; Patankar, A. V.; Gui, C.; Holmes, S.; Relman, D. A.
10.1101/2023.09.04.556257 — evolutionary biology — Posted on 2023-09-06
3996 Steady-State Regulation of COPII-Dependent Secretory Cargo Sorting by Inositol Trisphosphate Receptors, Calcium, and Penta EF Hand Proteins
Held, A.; Lapka, J.; Sargeant, J.; Hojanazarova, J.; Madreiter-Sokolowski, C.; Mali, R.; Graier, W. F.; Hay, J. C.
10.1101/2020.06.13.150144 — cell biology — Posted on 2023-09-06
3997 Highly multiplexed mRNA quantitation with CRISPR-Cas13
Kang, B.; Zhang, J.; Schwoerer, M. P.; Nelson, A. N.; Schoeman, E.; Guo, A.; Ploss, A.; Myhrvold, C.
10.1101/2023.08.16.553527 — molecular biology — Posted on 2023-09-06
3999 Evaluation of trans- and cis-4-fluorogabapentin for brain PET imaging
Zhou, Y.-P.; Normandin, M. D.; Belov, V.; Macdonald-Soccorso, M. T.; Moon, S.-H.; Sun, Y.; El Fakhri, G.; Guehl, N. J.; Brugarolas, P.
10.1101/2023.09.01.555353 — neuroscience — Posted on 2023-09-06
4001 Enhancing farmed striped catfish (Pangasianodon hypophthalmus) robustness using dietary β-glucan
Bano, S.; Khan, N.; Fatima, M.; Khalique, A.; Arslan, M.; Nazir, S.; Asghar, M.; Khizar, A.; Davies, S. J.; Wan, A. H. L.
10.1101/2023.09.02.556025 — zoology — Posted on 2023-09-06
4004 Topological evolution of sprouting vascular networks: from day-by-day analysis to general growth rules.
Rojek, K. O.; Wrzos, A.; Zukowski, S.; Bogdan, M.; Lisicki, M.; Szymczak, P.; Guzowski, J.
10.1101/2023.09.02.555959 — bioengineering — Posted on 2023-09-06
4005 Boiling histotripsy induces dendritic cell activation and acquisition of antigen in tumor draining lymph nodes
Thim, E. A.; Petricca, L. E.; Mathew, A. S.; Rivera-Escalera, F.; Elliott, M. R.; Bullock, T. N.; Price, R. J.
10.1101/2023.09.02.552844 — bioengineering — Posted on 2023-09-06
4006 The Genomic Legacy of Human Management and sex-biased Aurochs hybridization in Iberian Cattle
Günther, T.; Chisausky, J.; Galindo-Pellicena, M. A.; Iriarte, E.; Cortes Gardyn, O.; Eusebi, P. G.; Garcia-Gonzalez, R.; Urena, I.; Moreno, M.; Alday, A.; Rojo, M.; Perez, A.; Tejedor Rodriguez, C.; Garcia Martinez de Lagran, I.; Arsuaga, J. L.; Carretero, J.-M.; Götherström, A.; Smith, C.; Valdiosera, C.
10.1101/2023.07.19.548914 — genomics — Posted on 2023-09-06
4009 WITHDRAWN: Spatial enrichment of the type 1 interferon signature in the brain of a neuropsychiatric lupus murine model
Aw, E.; Lin, S. L.; Zhang, Y.; Herrmann, U.; Yalcin, E.; Langston, K.; Castrillion, C.; Ma, M.; Moffitt, J. R.; Carroll, M. C.
10.1101/2023.04.21.537814 — immunology — Posted on 2023-09-06
4010 Tauopathy severely disrupts homeostatic set-points in emergent neural dynamics but not in the activity of individual neurons.
McGregor, J. N.; Farris, C. A.; Ensley, S.; Schneider, A.; Wang, C.; Liu, Y.; Tu, J.; Elmore, H.; Ronayne, K. D.; Wessel, R.; Dyer, E. L.; Bhaskaran-Nair, K.; Holtzman, D. M.; Hengen, K. B.
10.1101/2023.09.01.555947 — neuroscience — Posted on 2023-09-06
4011 Biophysics of sodium channels during subthreshold depolarization in vitro and in silico
Köster, P. A.; Stiehl, T.; Tigerholm, J.; Maxion, A.; Namer, B.; Lampert, A.
10.1101/2023.09.03.556095 — physiology — Posted on 2023-09-06
4013 Vinculin is Essential For Sustaining Normal Levels of Endogenous Force Transmission at Cell-Cell Contacts
Mezher, M.; Dumbali, S.; Fenn, I.; Lamb, C.; Miller, C.; Cabe, J. I.; Bejar-Padilla, V.; Conway, D.; Maruthamuthu, V.
10.1101/2023.09.05.556369 — biophysics — Posted on 2023-09-06
4015 COVFlow: phylodynamics analyses of viruses from selected SARS-CoV-2 genome sequences
Danesh, G.; Boennec, C.; Verdurme, L.; Roussel, M.; Trombert, S.; Visseaux, B.; Haim-Boukobza, S.; Alizon, S.
10.1101/2022.06.17.496544 — bioinformatics — Posted on 2023-09-06
4017 Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
Bobby, M. L.; Fearon, D.; Ferla, M.; Filep, M.; Koekemoer, L.; Robinson, M. C.; The COVID Moonshot Consortium, ; Chodera, J. D.; Lee, A. A.; London, N.; von Delft, A.; von Delft, F.
10.1101/2020.10.29.339317 — biochemistry — Posted on 2023-09-06
4018 A single-cell atlas of the aging murine ovary
Isola, J.; Ocanas, S. R.; Hubbart, C.; Ko, S.; Ali Mondal, S.; Hense, J.; Carter, H. N. C.; Schneider, A.; Kovats, S.; Alberola-Ila, J.; Freeman, W. M.; Stout, M.
10.1101/2023.04.29.538828 — cell biology — Posted on 2023-09-06
4019 Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus
Burmeister, W. P.; Boutin, L.; Balestra, A. C.; Gröger, H.; Ballandras-Colas, A.; Hutin, S.; Kraft, C.; Grimm, C.; Böttcher, B.; Fischer, U.; Tarbouriech, N.; Iseni, F.
10.1101/2023.09.03.556150 — molecular biology — Posted on 2023-09-06
4023 Disruption of Ordered Membrane Domains as a Mechanism Underlying Neuropathic Pain
Handlin, L. J.; Macchi, N. L.; Dumaire, N.; Salih, L.; McCommis, K. S.; Moutal, A.; Dai, G.
10.1101/2023.09.02.556056 — biophysics — Posted on 2023-09-06
4024 Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes
Biswas, A.; Munoz, O.; Kim, K.; Hoege, C.; Lorton, B. M.; Shechter, D.; Guck, J.; Zaburdaev, V.; Reber, S.
10.1101/2023.09.05.556409 — biophysics — Posted on 2023-09-06
4025 Twisted plywood-like tissue formation in vitro. Does curvature do the twist?
Schamberger, B.; Ehrig, S.; Dechat, T.; Spitzer, S.; Bidan, C. M.; Fratzl, P.; Dunlop, J. W. C.; Roschger, A.
10.1101/2023.09.04.556075 — biophysics — Posted on 2023-09-06
4026 In situ cryoET reveals inhibitor-induced perturbations in Pf80S GTPase interactions
Anton, L.; Cheng, W.; Haile, M.; Cobb, D. W.; Zhu, X.; Han, L.; Li, E.; Nair, A.; Lee, C. L.; Ke, H.; Zhang, G.; Doud, E. H.; Ho, C.-M.
10.1101/2023.09.03.556115 — biophysics — Posted on 2023-09-06
4031 Rethinking sinking: Imaging the flow fields of natural marine aggregates to derive sinking velocity
Flintrop, C. M.; Ahmerkamp, S.; Moradi, N.; Klawonn, I.; März, J.; Hörstmann, C.; Kiko, R.; Khalili, A.; Grossart, H.-P.; Alvarez-Salgado, X. A.; Aristegui Ruiz, J.; Iversen, M. H.
10.1101/2023.09.05.555549 — biophysics — Posted on 2023-09-06
4032 Mechanistic modeling of amyloid oligomer and protofibril formation
Yuzu, K.; Imamura, H.; Nozaki, T.; Fujii, Y.; Badawy, S. M. M.; Morishima, K.; Okuda, A.; Inoue, R.; Sugiyama, M.; Chatani, E.
10.1101/2023.09.02.556028 — biophysics — Posted on 2023-09-06
4033 Single-Molecule Reaction-Diffusion
Xu, W.; Jazani, S.; Kilic, Z.; Presse, S.
10.1101/2023.09.05.556378 — biophysics — Posted on 2023-09-06
4035 A pangenomic atlas reveals that eco-evolutionary dynamics shape plant pathogen type VI secretion systems
Aoun, N.; Georgoulis, S. J.; Avalos, J. K.; Grulla, K. J.; Miqueo, K.; Tom, C.; Lowe-Power, T.
10.1101/2023.09.05.556054 — evolutionary biology — Posted on 2023-09-06
4036 FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-cadherin
Kizhatil, K.; Clark, G.; Sunderland, D.; Bhandari, A.; Horbal, L.; Balasubramanian, R.; John, S.
10.1101/2023.09.04.556253 — cell biology — Posted on 2023-09-06
4037 The tumor microbiome reacts to hypoxia and can influence response to radiation treatment in colorectal cancer
Benej, M.; Hoyd, R.; Kreamer, M.; Wheeler, C. E.; Grencewicz, D. J.; Choueiry, F.; Chan, C. H.; Zakharia, Y.; Ma, Q.; Dodd, R. D.; Ulrich, C. M.; Hardikar, S.; Churchman, M. L.; Tarhini, A. A.; Robinson, L. A.; Singer, E. A.; Ikeguchi, A. P.; McCarter, M. D.; Tinoco, G.; Husain, M.; Jin, N.; Tan, A. C.; Osman, A. E. G.; Eljilany, I.; Riedlinger, G.; Schneider, B. P.; Benejova, K.; Kery, M.; Papandreou, I.; Zhu, J.; Denko, N.; Spakowicz, D.
10.1101/2023.09.01.555936 — immunology — Posted on 2023-09-06
4038 A tonically active master neuron continuously modulates mutually exclusive motor states at two timescales
Meng, J.; Ahamed, T.; Yu, B.; Hung, W.; El Mouridi, S.; Zhang, Z.; Wang, Z.; Wen, Q.; Boulin, T.; Gao, S.; Zhen, M.
10.1101/2022.04.06.487231 — neuroscience — Posted on 2023-09-06
4040 Novel Insights into the Aortic Mechanical Properties of Mice Modeling Hereditary Aortic Diseases
Dubacher, N.; Sugiyama, K.; Smith, J. D.; Nussbaumer, V.; Csonka, M.; Ferenczi, S.; Kovacs, K. J.; Caspar, S. M.; Lamberti, L.; Meienberg, J.; Yanagisawa, H.; Sheppard, M. B.; Matyas, G.
10.1101/2023.08.15.553452 — pathology — Posted on 2023-09-06
4041 The shared ancestry between the C9orf72 hexanucleotide repeat expansion and intermediate-length alleles using haplotype sharing trees and HAPTK
Rautila, O. S.; Kaivola, K.; Rautila, H.; Hokkanen, L.; Launes, J.; Strandberg, T. E.; Laaksovirta, H.; Palmio, J.; Tienari, P. J.
10.1101/2023.07.28.550820 — genetics — Posted on 2023-09-06
4042 The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks
van de Kooij, B.; van der Wal, F. J.; Rother, M. B.; Creixell, P.; Stout, M.; Wiegant, W.; Joughin, B. A.; Vornberger, J.; van Vugt, M. A. T. M.; Altmeyer, M.; Yaffe, M. B.; van Attikum, H.
10.1101/2023.09.05.556391 — molecular biology — Posted on 2023-09-06
4046 Widespread, depth-dependent cortical microstructure alterations in paediatric focal epilepsy
Casella, C.; Vecchiato, K.; Cromb, D.; Guo, Y.; Winkler, A. M.; Hughes, E.; Dillon, L.; Green, E.; Colford, K.; Egloff, A.; Siddiqui, A.; Price, A.; Cordero Grande, L.; Wood, T. C.; Malik, S.; Teixeira, R. P. A. G.; Carmichael, D. W.; O'Muircheartaigh, J.
10.1101/2022.11.29.518330 — neuroscience — Posted on 2023-09-06
4047 Laws for Glia Organization Conserved Across Mammals
Pinto-Duarte, A.; Bogue, K.; Sejnowski, T. J.; Srinivasan, S.
10.1101/449421 — neuroscience — Posted on 2023-09-06
4048 Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry & high-resolution microscopy
Hegewisch-Solloa, E.; Melsen, J. E.; Ravichandran, H.; Rendeiro, A.; Mundy-Bosse, B.; Freud, A. G.; Melms, J. C.; Eisman, S. E.; Izar, B.; Grunstein, E.; Connors, T. J.; Elemento, O.; Horowitz, A.; Mace, E. M.
10.1101/2023.09.05.556371 — immunology — Posted on 2023-09-06
4049 Interdependence of a kinase and its cognate substrate plasma membrane nanoscale dynamics underlies Arabidopsis response to viral infection
Jolivet, M.-D.; Deroubaix, A.-F.; Boudsocq, M.; Abel, N. B.; Rocher, M.; Robbe, T.; Wattelet, V.; Huard, J.; Lefebvre, D.; Lu, Y.-J.; Day, B.; Saias, G.; Ahmed, J.; Cotelle, V.; Giovinazzo, N.; Gallois, J.-L.; Yamaji, Y.; German-Retana, S.; Gronnier, J.; Ott, T.; Mongrand, S.; Germain, V.
10.1101/2023.07.31.551174 — plant biology — Posted on 2023-09-06
4051 Repair of DNA double-strand breaks leaves heritable impairment to genome function
Bantele, S. C.; Mordini, I.; Biran, A.; Alcaraz, N.; Wenger, A.; Krietenstein, N.; Groth, A.; Lukas, J.
10.1101/2023.08.29.555258 — cell biology — Posted on 2023-09-06
4054 Alterations of the TGFb-sequestration complex member ADAMTSL1 levels are associated with muscular defects and rhabdomyosarcoma aggressiveness
Bertrand-Chapel, A.; Meyer, S.; Juban, G.; Kneppers, A. E. M.; Huchede, P.; Gallerne, C.; Benayoun, R.; Cohen, E.; Lopez-Gonzalez, A.; Larbi, S. B.; Creveaux, M.; Vaille, L.; Bouvier, A.; Theodore, M.; Broutier, L.; Dutour, A.; Cordier-Bussat, M.; Blay, J.-Y.; Streichenberger, N.; Picard, C.; Corradini, N.; Allamand, V.; Mounier, R.; Castets, P.; CASTETS, M.
10.1101/2023.03.07.531559 — cancer biology — Posted on 2023-09-06
4056 Caliban: Accurate cell tracking and lineage construction in live-cell imaging experiments with deep learning
Schwartz, M.; Moen, E.; Miller, G.; Dougherty, T.; Borba, E.; Ding, R.; Graf, W.; Pao, E.; Van Valen, D. A.
10.1101/803205 — bioinformatics — Posted on 2023-09-06
4057 Repeat turnover meets stable chromosomes: repetitive DNA sequences mark speciation and gene pool boundaries in sugar beet and wild beets
Schmidt, N.; Sielemann, K.; Breitenbach, S.; Fuchs, J.; Pucker, B.; Weisshaar, B.; Holtgräwe, D.; Heitkam, T.
10.1101/2023.09.01.555723 — genomics — Posted on 2023-09-06
4058 Uncharacterized yeast gene YBR238C, an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via HAP4- and RMD9-dependent mechanisms
Alfatah, M.; Jolyn, J. L. J.; Zhang, Y.; Naaz, A.; Trishia, C. Y. N.; Yogasundaram, S.; Faidzinn, N. A.; Jovian, J. L.; Eisenhaber, B.; Eisenhaber, F.
10.1101/2023.07.04.547743 — genetics — Posted on 2023-09-06
4061 IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer
van Baarle, L.; De Simone, V.; Schneider, L.; Santhosh, S.; Abdurahiman, S.; Biscu, F.; Schneider, R.; Zanoletti, L.; Verbandt, S.; Hu, Z.; Stakenborg, M.; Ke, B.-J.; Garcia-Reyes, B.; Henn, J.; Toma, M.; Vanmechelen, M.; De Smet, F.; Ibiza, S.; Tejpar, S.; Wehner, S.; Matteoli, G.
10.1101/2023.06.01.543246 — cancer biology — Posted on 2023-09-06
4063 CREBBP lysine acetyltransferase domain mutations create zombie enzymes that alter chromatin loading dynamics and prevent EP300 redundancy
Yang, H.; Zhang, W.; Ravanmehr, V.; Mechaly, A.; Regad, L.; Haouz, A.; Chen, R.; Henderson, J.; Rojas, E.; Wilson, A.; Parsons, S.; Nastoupil, L.; Davis, R. E.; Deng, Q.; Samaniego, F.; Rodrigues-Lima, F.; Green, M. R.
10.1101/2023.09.05.556242 — cancer biology — Posted on 2023-09-05
4066 Germ cells do not progress through spermatogenesis in the infertile zebrafish testis
Sposato, A. L.; Llewellyn, D. R.; Weber, J. M.; Hollins, H. L.; Schrock, M. N.; Farrell, J. A.; Gagnon, J. A.
10.1101/2023.09.05.556432 — developmental biology — Posted on 2023-09-05
4068 Pervasive mislocalization of pathogenic coding variants underlying human disorders
Lacoste, J.; Haghighi, M.; Haider, S.; Lin, Z.-Y.; Segal, D.; Reno, C.; Qian, W. W.; Xiong, X.; Shafqat-Abbasi, H.; Ryder, P.; Senft, R.; Cimini, B.; Roth, F.; Calderwood, M.; Hill, D.; Vidal, M.; Yi, S.; Sahni, N.; Peng, J.; Gingras, A.-C.; Singh, S.; Carpenter, A.; Taipale, M.
10.1101/2023.09.05.556368 — cell biology — Posted on 2023-09-05
4070 Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells
Chen, Y.; Gialeli, C.; Shen, J.; Duner, P.; Walse, B.; Duelli, A.; Caing-Carlsson, R.; Blom, A. M.; Zibert, J.; Hultgardh-Nilsson, A.; Alenfall, J.; Liang, C.; Nilsson, J. C.
10.1101/2023.09.05.556237 — cell biology — Posted on 2023-09-05
4071 Propofol-mediated loss of consciousness disrupts predictive routing and local field phase modulation of neural activity
Xiong, Y.; Donoghue, J. A.; Lundqvist, M.; Mahnke, M.; Major, A. J.; Brown, E. N.; Miller, E. K.; Bastos, A. M.
10.1101/2023.09.02.555990 — neuroscience — Posted on 2023-09-05
4072 Corticothalamic Neurons in Motor Cortex Have a Permissive Role in Motor Execution
Carmona, L. M.; Nelson, A.; Tun, L. T.; Kim, A.; Shiao, R.; Kissner, M. D.; Menon, V.; Costa, R. M.
10.1101/2022.09.20.508799 — neuroscience — Posted on 2023-09-05
4074 Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16
Wang, H.; Rizvi, S. R. A.; Dong, D.; Lou, J.; Wang, Q.; Sopipong, W.; Su, Y.; Najar, F.; Agarwal, P.; Kozielski, F. G.; Haider, S.
10.1101/2022.12.23.521761 — biophysics — Posted on 2023-09-05
4078 Establishing a comprehensive web-based analysis platform for Nicotiana benthamiana genome and transcriptome
Kurotani, K.-i.; Hirakawa, H.; Shirasawa, K.; Tagiri, K.; Mori, M.; Ichihashi, Y.; Suzuki, T.; Tanizawa, Y.; Nakamura, Y.; Isobe, S.; Notaguchi, M.
10.1101/2023.09.03.556139 — plant biology — Posted on 2023-09-05
4079 The SLC1A1/EAAT3 Dicarboxylic Amino Acid Transporter is an Epigenetically Dysregulated Nutrient Carrier that Sustains Oncogenic Metabolic Programs
Grubb, T. M.; Khatun, J.; Matar, S.; Ghandour, F.; Dubasik, N.; Salem, C.; Orlando, D. A.; Guenther, M. G.; Martinez, S. R.; Koochaki, P.; Coker, J. A.; Tang, C.; Reznik, E.; Kotecha, R. R.; Hakimi, A. A.; Abdallah, N.; Weight, C. J.; Choueiri, T. K.; Asara, J. M.; Stauffer, S. R.; Signoretti, S.; Kaelin, W. G.; Chakraborty, A. A.
10.1101/2023.09.04.556240 — cancer biology — Posted on 2023-09-05
4081 Identify non-mutational p53 functional deficiency in human cancers
Li, Q.; Zhang, Y.; Luo, S.; Zhang, Z.; Oberg, A.; Kozono, D.; Lu, H.; Sarkaria, J. N.; Ma, L.; Wang, L.
10.1101/2022.07.28.501874 — bioinformatics — Posted on 2023-09-05
4082 EX VIVO GENE EDITING AND CELL THERAPY FOR HEREDITARY TYROSINEMIA TYPE 1
Ates, I.; Rathbone, T.; Stuart, C.; Barzi, M.; He, G.; Major, A. M.; Srinivasan, S.; Farris, A. B.; Bissig, K.-D.; Cottle, R. N.
10.1101/2023.09.04.555940 — bioengineering — Posted on 2023-09-05
4084 A thermostable phospholipase C obtained by consensus design
Val, D. S.; Di NArdo, L.; Marchisio, F.; Peiru, S.; Castelli, M. E.; Abriata, L.; Menzella, H. G.; Rasia, R.
10.1101/2022.10.06.511049 — biochemistry — Posted on 2023-09-05
4085 A short course of antibiotics selects for persistent resistance in the human gut
Yaffe, E.; Dethlefsen, L.; Patankar, A. V.; Gui, C.; Holmes, S.; Relman, D. A.
10.1101/2023.09.04.556257 — evolutionary biology — Posted on 2023-09-05
4090 Gene and protein sequence features augment HLA class I ligand predictions
Bresser, K.; Nicolet, B.; Jeko, A.; Wu, W.; Loayza-Puch, F.; Agami, R.; Heck, A. J. R.; Wolkers, M. J. R.; Schumacher, T.
10.1101/2023.09.03.556079 — immunology — Posted on 2023-09-05
4093 Gut mucosal cells transfer alpha-synuclein to the vagus nerve
Chandra, R.; Sokratian, A.; Chavez, K. R.; King, S.; Swain, S. M.; Snyder, J. C.; West, A. B.; Liddle, R. A.
10.1101/2023.08.14.553305 — neuroscience — Posted on 2023-09-05
4095 Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina
Wu, E. G.; Brackbill, N.; Rhoades, C. E.; Kling, A.; Gogliettino, A. R.; Shah, N. P.; Sher, A.; Litke, A. M.; Simoncelli, E. P.; Chichilnisky, E. J.
10.1101/2023.08.12.552902 — neuroscience — Posted on 2023-09-05
4096 Robust nuclease-dead S. aureus dCas9-mediated alpha-synuclein knockdown in substantia nigra in a humanized mouse model of Parkinson's disease
Torres, C. A. M.; Zafar, F.; Sastre, D.; Hermesky, D.; Chen, M. Y.; Vazquez, J. P.; Qi, L. S.; Kirik, D.; Schüle, B.
10.1101/2023.09.05.556425 — neuroscience — Posted on 2023-09-05
4097 A transcription factor module mediating C2 photosynthesis
Dickinson, P. J.; Triesch, S.; Schlüter, U.; Weber, A. P. M.; Hibberd, J. M.
10.1101/2023.09.05.556297 — plant biology — Posted on 2023-09-05
4100 Inferring cell trajectories of spatial transcriptomics via optimal transport analysis
Shen, X.; Huang, K.; Zuo, L.; Ye, Z.; Li, Z.; Yu, Q.; Zou, X.; Wei, X.; Xu, P.; Jin, X.; Xu, X.; Wu, L.; Zhu, H.; Qin, P.
10.1101/2023.09.04.556175 — bioinformatics — Posted on 2023-09-05
4102 The potential of plasma HLA peptides beyond neoepitopes
Wahle, M.; Thielert, M.; Zwiebel, M.; Skowronek, P.; Zeng, W.-F.; Mann, M.
10.1101/2023.09.05.556309 — biochemistry — Posted on 2023-09-05
4103 Light-induced Trpin/Metout switching during BLUF domain activation in ATP-bound photoactivatable adenylate cyclase OaPAC
Chretien, A.; Nagel, M. F.; Botha, S.; de Wijn, R.; Brings, L.; Doerner, K.; Han, H.; Koliyadu, J. C. P.; Letrun, R.; Round, A.; Sato, T.; Schmidt, C.; Secareanu, R.-C.; von Stetten, D.; Vakili, M.; Wrona, A.; Bean, R.; Mancuso, A.; Schulz, J.; Pearson, A. R.; Kottke, T.; Lorenzen, K.; Schubert, R.
10.1101/2023.09.05.556344 — biochemistry — Posted on 2023-09-05
4108 Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2
Bulos, M. L.; Grzelak, E. M.; Li-Ma, C.; Chen, E.; Hull, M.; Johnson, K. A.; Bollong, M. J.
10.1101/2023.04.19.537449 — cell biology — Posted on 2023-09-05
4110 The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks
van de Kooij, B.; van der Wal, F. J.; Rother, M. B.; Creixell, P.; Stout, M.; Wiegant, W.; Joughin, B. A.; Vornberger, J.; Altmeyer, M.; Yaffe, M. B.; van Attikum, H.
10.1101/2023.09.05.556391 — molecular biology — Posted on 2023-09-05
4111 SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction
Flaherty, S. E.; Bezy, O.; Paulhus, B. L.; Song, L.; Piper, M.; Pang, J.; Park, Y.; Asano, S.; Lien, Y.-C.; Griffin, J. D.; Robertson, A.; Opsahl, A.; Shanthappa, D. H.; Ahn, Y.; Pashos, E.; Simmons, R. G.; Birnbaum, M. J.; Wu, Z.
10.1101/2023.09.05.555087 — molecular biology — Posted on 2023-09-05
4113 Mettl1-dependent m7G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster
Kaneko, S.; Miyoshi, K.; Tomuro, K.; Terauchi, M.; Kondo, S.; Tani, N.; Ishiguro, K.-I.; Toyoda, A.; Noguchi, H.; Iwasaki, S.; Saito, K.
10.1101/2023.09.04.555845 — molecular biology — Posted on 2023-09-05
4114 KAT2 paralogs prevent dsRNA accumulation and interferon signaling to maintain intestinal stem cells
Nguyen, M.-U. T.; Potgieter, S.; Huang, W.; Pfeffer, J.; Woo, S.; Zhao, C.; Lawlor, M.; Yang, R.; Halstead, A.; Dent, S.; Saenz, J.; Zheng, H.; Yuan, Z.-F.; Sidoli, S.; Ellison, C. E.; Verzi, M.
10.1101/2023.09.04.556156 — molecular biology — Posted on 2023-09-05
4115 Mitotic chromatin marking governs asymmetric segregation of DNA damage
Ferrand, J.; Dabin, J.; Chevallier, O.; Kupai, A.; Rothbart, S. B.; Polo, S. E.
10.1101/2023.09.04.556166 — molecular biology — Posted on 2023-09-05
4117 Microbially-conjugated Bile Salts Found in Human Bile Activate the Bile Salt Receptors TGR5 and FXR.
Ay, U.; Lenicek, M.; Haider, R. S.; Classen, A.; van Eijk, H.; Koelfat, K. V. K.; van der Kroft, G.; Neumann, U. P.; Hoffmann, C.; Bolm, C.; Olde Damink, S. W. M.; Schaap, F. G.
10.1101/2023.09.04.556292 — molecular biology — Posted on 2023-09-05
4118 Small protein mediates inhibition of ammonium transport in Methanosarcina mazei - an ancient mechanism?
Habenicht, T.; Weidenbach, K.; Velazquez-Campoy, A.; Martinez-Buey, R.; Balsera, M.; Schmitz, R. A.
10.1101/2023.09.04.555848 — molecular biology — Posted on 2023-09-05
4119 High-confidence 3D template matching for cryo-electron tomography
Cruz-Leon, S.; Majtner, T.; Hoffmann, P. C.; Kreysing, J. P.; Tuijtel, M. W.; Schaefer, S. L.; Geissler, K.; Beck, M.; Turonova, B.; Hummer, G.
10.1101/2023.09.05.556310 — molecular biology — Posted on 2023-09-05
4122 Phytohormones regulate asexual Toxoplasma gondii
Wagner, T.; Bangoura, B.; Wiedmer, S.; Daugschies, A.; Dunay, I. R.
10.1101/2023.09.05.556389 — microbiology — Posted on 2023-09-05
4125 Virion-associated US28 rapidly modulates Akt activity to suppress HCMV lytic replication in monocytes
Mahmud, J.; Geiler, B. W.; Biswas, J.; Miller, M. J.; Myers, J. E.; Matthews, S. M.; Wass, A. B.; O'Connor, C. M.; Chan, G. C.
10.1101/2023.09.05.556359 — microbiology — Posted on 2023-09-05
4127 A genetic screen identifies a role for oprF in Pseudomonas aeruginosa biofilm stimulation by subinhibitory antibiotics
Yaeger, L. N.; Ranieri, M. R. M.; Chee, J.; Karabelas-Pittman, S.; Rudolph, M.; Giovannoni, A.; Harvey, H.; Burrows, L. L.
10.1101/2023.09.05.556382 — microbiology — Posted on 2023-09-05
4128 International and regional spread of carbapenem-resistant Klebsiella pneumoniae in Europe
Budia Silva, M.; Kostyanev, T.; Ayala Montano, S.; Bravo-Ferrer Acosta, J. M.; Garcia-Castillo, M.; Canton, R.; Goossens, H.; Rodriguez-Bano, J.; Grundmann, H.; Reuter, S.; EURECA/WP1B Group,
10.1101/2023.09.05.556311 — microbiology — Posted on 2023-09-05
4132 An atypical endomembrane localized CNL-type immune receptor with a conserved deletion in the N-terminal signaling domain functions in cell death and immunity
Sunil, S.; Beeh, S.; Stoebbe, E.; Fischer, K. M.; Wilhelm, F.; Paris, C.; Meral, A.; Teasdale, L.; Jiang, Z.; Zhang, l.; Aguilar Parras, E.; Nuernberger, T.; Weigel, D.; Lozano-Duran, R.; El Kasmi, F.
10.1101/2023.09.04.556214 — plant biology — Posted on 2023-09-05
4133 Predicting Permeation of Compounds across the Outer Membrane of P. aeruginosa Using Molecular Descriptors: Advantages and Limitations
Manrique, P. D.; Leus, I.; Lopez, C. A.; Mehla, J.; Malloci, G.; Gervasoni, S.; Vargiu, A.; Kinthada, R.; Herndon, L.; Hengartner, N.; Walker, J. K.; Rybenkov, V.; Ruggerone, P.; Zgurskaya, H.; Gnanakaran, S.
10.1101/2023.09.02.555818 — biophysics — Posted on 2023-09-05
4134 Multi-method quantification of acetyl-CoA and further acyl-CoA species in normal and ischemic rat liver
Tokarska-Schlattner, M.; Zeaiter, N.; Cunin, V.; Attia, S.; Meunier, C.; Kay, L.; Achouri, A.; Hiriart-Bryant, E.; Couturier, K.; Tellier, C.; El Harras, A.; Elena-Herrmann, B.; Khochbin, S.; Le Gouellec, A.; Schlattner, U.
10.1101/2023.09.04.556259 — biochemistry — Posted on 2023-09-05
4139 Local recurrent circuits modulate visual center and surround interactions in the mouse superior colliculus
Cui, P.; Song, K.; Mariatos Metaxas, D.; Isla, A. G.; Femenia, T.; Lazaridis, I.; Meletis, K.; Kumar, A.; Kardamakis, A. A.
10.1101/2023.09.03.556096 — neuroscience — Posted on 2023-09-05
4140 An integrated approach to identify sex-specific genes, transcription factors, and pathways in Alzheimer's disease
Lopez-Cerdan, A.; Andreu, Z.; Hidalgo, M. R.; de la Iglesia-Vaya, M.; Mikozami, A.; Guerini, F. R.; Garcia-Garcia, F.
10.1101/2023.09.05.556293 — neuroscience — Posted on 2023-09-05
4152 Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning
Laubscher, E.; Wang, X.; Razin, N.; Dougherty, T.; Xu, R.; Ombelets, L.; Pao, E.; Moffitt, J.; Yue, Y.; Van Valen, D. A.
10.1101/2023.09.03.556122 — bioinformatics — Posted on 2023-09-05
4154 Characterizing tissue structures from spatial omics with spatial cellular graph partition
Wu, Z.; Kondo, A.; McGrady, M.; Baker, E. A. G.; Wu, E.; Rahim, M. K.; Bracey, N. A.; Charu, V.; Cho, R. J.; Cheng, J. B.; Afkarian, M.; Zou, J.; Mayer, A. T.; Trevino, A. E.
10.1101/2023.09.05.556133 — bioinformatics — Posted on 2023-09-05
4157 Dietary 14C reservoir effects and the chronology of prehistoric burials at Sakhtysh, central European Russia
Meadows, J.; Khramtsova, A.; Kostyleva, E.; Vasilyev, S.; Veselovskaya, E.; Dobrovolskaya, M.; da Silva, N. A.; Krause-Kyora, B.; Piezonka, H.
10.1101/2023.09.04.555011 — ecology — Posted on 2023-09-05
4159 Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus
Burmeister, W. P.; Boutin, L.; Balestra, A. C.; Gröger, H.; Ballandras-Colas, A.; Hutin, S.; Kraft, C.; Grimm, C.; Böttcher, B.; Fischer, U.; Tarbouriech, N.; Iseni, F.
10.1101/2023.09.03.556150 — molecular biology — Posted on 2023-09-05
4160 Neutralization Escape by SARS-CoV-2 Omicron Subvariant BA.2.86
Lasrado, N.; Collier, A.-r.; Hachmann, N.; Miller, J.; Rowe, M.; Schonberg, E.; Rodrigues, S.; LaPiana, A.; Patio, R.; Anand, T.; Fisher, J.; Mazurek, C.; Guan, R.; Wagh, K.; Theiler, J.; Korber, B.; Barouch, D. H.
10.1101/2023.09.04.556272 — microbiology — Posted on 2023-09-05
4161 Understanding the heterogeneity of alloreactive natural killer cell function inkidney transplantation
Ruan, D. F.; Fribourg, M.; Yuki, Y.; Park, Y.-H.; Martin, M.; Kelly, G.; Lee, B.; Lee, R.; de Real, R. M.; Geanon, D.; Kim-Schulze, S.; McCarthy, M.; Chun, N.; Cravedi, P.; Carrington, M.; Heeger, P.; Horowitz, A.
10.1101/2023.09.01.555962 — immunology — Posted on 2023-09-05
4164 Axon guidance during CNS regeneration is required for specific brain innervation
Delpech, C.; Schaeffer, J.; Vilallongue, N.; Benadjal, A.; Blot, B.; Excoffier, B.; Plissonnier, E.; Albert, F.; Paccard, A.; Zagar, Y.; Castellani, V.; BELIN, S.; Chedotal, A.; NAWABI, H.
10.1101/2023.09.04.556244 — neuroscience — Posted on 2023-09-05
4167 Reliability of the TMS-evoked potential in dorsolateral prefrontal cortex
Gogulski, J. D.; Cline, C. C.; Ross, J. M.; Parmigiani, S.; Keller, C. J.
10.1101/2023.09.04.556283 — neuroscience — Posted on 2023-09-05
4174 Competitive integration of time and reward explains value-sensitive foraging decisions and frontal cortex ramping dynamics
Bukwich, M.; Campbell, M. G.; Zoltowski, D.; Kingsbury, L.; Tomov, M. S.; Stern, J.; Kim, H. R.; Drugowitsch, J.; Linderman, S. W.; Uchida, N.
10.1101/2023.09.05.556267 — neuroscience — Posted on 2023-09-05
4175 Neuronal FOS reports synchronized activity of presynaptic neurons
Anisimova, M.; Lamothe-Molina, P. J.; Franzelin, A.; Aberra, A. S.; Hoppa, M. B.; Gee, C. E.; Oertner, T. G.
10.1101/2023.09.04.556168 — neuroscience — Posted on 2023-09-05
4177 Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need
Tan, B.; Browne, C. J.; Nobauer, T.; Vaziri, A.; Friedman, J. M.; Nestler, E. J.
10.1101/2023.09.03.556059 — neuroscience — Posted on 2023-09-05
4179 Transcranial magnetic stimulation of primary motor cortex elicits a site-specific immediate transcranial evoked potential
Beck, M. M.; Christiansen, L.; Madsen, M. A. J.; Jadidi, A. F.; Vinding, M. C.; Thielscher, A.; Bergmann, T. O.; Siebner, H. R.; Tomasevic, L.
10.1101/2023.09.05.556160 — neuroscience — Posted on 2023-09-05
4180 3D human retinal organoid model for the study of early diabetic retinopathy
de Lemos, L.; Antas, P.; Ferreira, I. S.; Santos, I. P.; Gomes, C. M.; Brito, C.; Seabra, M. C.; Tenreiro, S.
10.1101/2023.09.04.556258 — neuroscience — Posted on 2023-09-05
4183 Spatial distribution and functional integration of displaced ipRGCs
Duda, S.; Block, C. T.; Pradhan, D. R.; Arzhangnia, Y.; Greschner, M.; Puller, C.
10.1101/2023.09.05.556383 — neuroscience — Posted on 2023-09-05
4187 A role for JAK2 in mediating cell surface GHR-PRLR interaction
Chen, C.; Jiang, J.; Rao, T. C.; Marquez Lago, T. T.; Frank, S. J.; Leier, A.
10.1101/2023.09.01.555812 — biophysics — Posted on 2023-09-05
4188 G-PLIP: Knowledge graph neural network for structure-free protein-ligand affinity prediction
Crouzet, S. J.; Lieberherr, A. M.; Atz, K.; Nilsson, T.; Sach-Peltason, L.; Muller, A. T.; Dal Peraro, M.; Zhang, J. D.
10.1101/2023.09.01.555977 — bioinformatics — Posted on 2023-09-05
4189 Autometa 2: A versatile tool for recovering genomes from highly-complex metagenomic communities
Rees, E. R.; Uppal, S.; Clark, C.; Lail, A. J.; Waterworth, S. C.; Roesemann, S. D.; Wolf, K. A.; Kwan, J. C.
10.1101/2023.09.01.555939 — bioinformatics — Posted on 2023-09-05
4191 Efficient ultrasound-mediated drug delivery to orthotopic liver tumors: Direct comparison of doxorubicin-loaded nanobubbles and microbubbles
Nittayacharn, P. A.; Abenojar, E.; Cooley, M. B.; Berg, F.; Counil, C.; Sojahrood, A.; Khan, M. S.; Yang, C.; Berndl, E.; Golczak, M.; Kolios, M.; Exner, A.
10.1101/2023.09.01.555196 — bioengineering — Posted on 2023-09-05
4194 Probucol mitigates high-fat diet-induced cognitive and social impairments through disruption of redox-inflammation association
Wu, H.-M.; Huang, N.-J.; Yang, Y. V.; Fan, L.-P.; Tang, T.-Y.; Liu, L.; Xu, Y.; Liu, D.-T.; Cai, Z.-X.; Ren, X.-Y.; Yao, Z.-H.; Chen, J.-Z.; Huang, X.; Zhang, C.; You, X.; Wang, C.; He, Y.; Ye, Z.-Y.; Hong, W.; Lin, S.-C.; Zhan, Y.-H.; Lin, S.-Y.
10.1101/2023.09.05.556289 — animal behavior and cognition — Posted on 2023-09-05
4196 A General Approach to Adjusting Genetic Studies for Assortative Mating
Bilghese, M.; Manansala, R.; Jaishankar, D.; Jala, J.; Benjamin, D. J.; Kimball, M.; Auer, P. L.; Livermore, M. A.; Turley, P.
10.1101/2023.09.01.555983 — genomics — Posted on 2023-09-05
4198 Response of siliceous marine organisms to the Permian-Triassic climate crisis based on new findings from central Spitsbergen, Svalbard
Foster, W. J.; Astryan, G.; Rauzi, S.; Botting, J.; Buchwald, S.; Lazarus, D.; Isson, T.; Renaudie, J.; Kiessling, W.
10.1101/2023.09.01.555975 — evolutionary biology — Posted on 2023-09-05
4200 Magnetoelectrics Enables Large Power Delivery to mm-Sized Wireless Bioelectronics
Kim, W.; Tuppen, C. A.; Alrashdan, F.; Singer, A.; Weirnick, R.; Robinson, J. T.
10.1101/2023.09.01.555944 — neuroscience — Posted on 2023-09-05
4201 Astrocytes modulate neuronal development by S100A6 signaling
Harkany, T.; Cinquina, V.; Calvigioni, D.; Piscitelli, F.; Keimpema, E.; Di Marzo, V.; Verkhratsky, A.
10.1101/2023.09.05.556314 — neuroscience — Posted on 2023-09-05
4202 Tauopathy severely disrupts homeostatic set-points in emergent neural dynamics but not the activity of individual neurons.
McGregor, J. N.; Farris, C. A.; Ensley, S.; Schneider, A.; Wang, C.; Liu, Y.; Tu, J.; Elmore, H.; Ronayne, K. D.; Wessel, R.; Dyer, E. L.; Bhaskaran-Nair, K.; Holtzman, D. M.; Hengen, K. B.
10.1101/2023.09.01.555947 — neuroscience — Posted on 2023-09-05
4204 Changes in lipid metabolism track with the progression of neurofibrillary pathology in tauopathies.
Olesova, D.; Dobesova, D.; Majerova, P.; Brumanova, R.; Kvasnicka, A.; Kouril, S.; Stevens, E.; Hanes, J.; Fialova, L.; Michalicova, A.; Piestansky, J.; Friedecky, D.; Kovac, A.
10.1101/2023.09.05.556321 — neuroscience — Posted on 2023-09-05
4211 Localization of four class I glutaredoxins in the cytosol and the secretory pathway and characterization of their biochemical diversification
Schloesser, M.; Moseler, A.; Bodnar, Y.; Homagk, M.; Wagner, S.; Pedroletti, L.; Gellert, M.; Ugalde, J. M.; Lillig, C. H.; Meyer, A. J.
10.1101/2023.09.01.555924 — plant biology — Posted on 2023-09-05
4212 The role of sphingosine-1-phosphate receptor 2 in mouse retina light responses
Shrestha, A. P.; Stiles, M.; Grambergs, R. C.; Boff, J. M.; Madireddy, S.; Mondal, K.; Rajmanna, R.; Porter, H.; Sherry, D.; Proia, R. L.; Vaithianathan, T.; Mandal, N.
10.1101/2023.09.01.555709 — physiology — Posted on 2023-09-05
4213 Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis
Shelton, S. D.; House, S.; Ramesh, V.; Chen, Z.; Wei, T.; Wang, X.; Llamas, C. B.; Venigalla, S. S.; Menezes, C. J.; Zhao, Z.; Gill, J. G.; DeBerardinis, R. J.; Morrison, S. J.; Tasdogan, A.; Mishra, P.
10.1101/2023.09.01.555986 — cancer biology — Posted on 2023-09-05
4214 STING activation counters glioblastoma by vascular alteration and immune surveillance
Joseph, J. V.; Blaavand, M. S.; Cai, H. K.; Vernejoul, F.; Knopper, R. W.; Lindhardt, T. B.; Skipper, K. K.; Axelgaard, E. K.; Reinert, L. K.; Giehm Mikkelsen, J. G.; Borghammer, P.; Degn, S. E.; Perouzel, E.; Hager, H.; Hansen, B.; Kalucka, J. M.; Vendelbo, M.; Paludan, S. R.; Thomsen, M. K.
10.1101/2023.09.03.556091 — cancer biology — Posted on 2023-09-05
4215 MCT4 and CD147 co-localize with MMP14 in invadopodia and autolysosomes and collectively stimulate breast cancer cell invasion by increasing extracellular matrix degradation
Meng, S.; Sorensen, E. E.; Ponniah, M.; Thorlacius-Ussing, J.; Crouigneau, R.; Borre, M. T.; Willumsen, N.; Flinck, M.; Pedersen, S. F.
10.1101/2023.09.03.556100 — cancer biology — Posted on 2023-09-05
4216 HOXB13 alters chromatin accessibility in prostate cancer through interactions with the SWI/SNF complex
Lingadahalli, S.; Fazlioglu, B. E.; Altintas, U. B.; Cingoz, A.; Tekoglu, E.; Yu, I. P. L.; Andomat, H.; Kulac, I.; Morova, T.; Xiao, K.; Dikbas, U. M.; Gleave, M.; Fazli, L.; Cejas, P.; Long, H.; Cherkasov, A.; Zwart, W.; Collins, C.; Bagci-Onder, T.; Lack, N. A.
10.1101/2023.09.04.556101 — cancer biology — Posted on 2023-09-05
4217 Leukemia circulation kinetics revealed through blood exchange method
Miller, A. B.; Langenbucher, A.; Rodriguez, F. H.; Lin, L.; Bray, C.; Duquette, S.; Zhang, Y.; Goulet, D.; Lane, A. A.; Weinstock, D. M.; Hemann, M. T.; Manalis, S. R.
10.1101/2023.09.03.556043 — cancer biology — Posted on 2023-09-05
4219 Enhanced protective efficacy of a novel, thermostable, RBD-S2 fusion immunogen against SARS-CoV-2 and its variants
Mittal, N.; Kumar, S.; Rajmani, R. S.; Singh, R.; Lemoine, C.; Jakob, V.; BJ, S.; Jagannath, N.; Bhat, M.; Chakraborty, D.; Pandey, S.; Jory, A.; S.A., S. S.; Kleanthous, H.; Dubois, P.; Ringe, R. P.; Varadarajan, R.
10.1101/2023.03.19.533338 — biophysics — Posted on 2023-09-05
4223 Borrelia burgdorferi PlzA is a cyclic-di-GMP dependent DNA- and RNA-binding protein
Jusufovic, N.; Krusenstjerna, A. C.; Savage, C.; Saylor, T. C.; Brissette, C. A.; Zueckert, W. R.; Schlax, P.; MOTALEB, M. A. R.; Stevenson, B.
10.1101/2023.01.30.526351 — microbiology — Posted on 2023-09-05
4226 Efficient gene knockout and genetic interactions: the IN4MER CRISPR/Cas12a multiplex knockout platform
Esmaeili Anvar, N.; Lin, C.; Ma, X.; Wilson, L. L.; Steger, R.; Sangree, A. K.; Colic, M.; Wang, S. H.; Doench, J. G.; Hart, T.
10.1101/2023.01.03.522655 — systems biology — Posted on 2023-09-05
4228 Evaluation of neural regulation and microglial responses to brain injury in larval zebrafish exposed to perfluorooctane sulfonate
Paquette, S. E.; Martin, N. R.; Rodd, A. L.; Manz, K. E.; Camarillo, M. A.; Allen, E.; Weller, H.; Pennell, K.; Plavicki, J. S.
10.1101/2022.09.30.510316 — neuroscience — Posted on 2023-09-05
4230 Interdependence of a kinase and its cognate substrate plasma membrane nanoscale dynamics underlies Arabidopsis response to viral infection
JOLIVET, M.-D.; Deroubaix, A.-F.; Boudsocq, M.; Abel, N. B.; Rocher, M.; Robbe, T.; Wattelet, V.; Huard, J.; Lefebvre, D.; Lu, Y.-J.; Day, B.; Saias, G.; Ahmed, J.; Cotelle, V.; Giovinazzo, N.; Gallois, J.-L.; Yamaji, Y.; German-Retana, S.; Gronnier, J.; Ott, T.; MONGRAND, S.; Germain, V.
10.1101/2023.07.31.551174 — plant biology — Posted on 2023-09-05
4231 Molecular tuning of sea anemone stinging
He, L. S.; Qi, Y.; Allard, C. A.; Valencia-Montoya, W. A.; Krueger, S. P.; Weir, K.; Seminara, A.; Bellono, N. W.
10.1101/2023.06.15.545144 — physiology — Posted on 2023-09-05
4234 Passive surveillance for shrimp pathogens in Penaeus vannamei submitted from 3 Regions of Latin America
Intriago, P.; Medina, A.; Cercado, N.; Arteaga, K.; Montenegro, A.; Burgos, M.; Espinoza, J.; Brock, J. A.; McInstosh, R.; Flegel, T.
10.1101/2023.08.29.555391 — pathology — Posted on 2023-09-05
4235 Small Extracellular Vesicles from Failing Heart Accelerate Tumor Growth
Caller, T.; Rotem, I.; Shaihov Teper, O.; Lendengolts, D.; Schary, Y.; Shai, R.; Glick Saar, E.; Dominissini, D.; Motie, M.; Katzir, I.; Popovtzer, R.; Nahmoud, M.; Boomgarden, A.; DSouza Schorey, C.; Naftali Shani, N.; Leor, J.
10.1101/2023.09.03.555686 — cancer biology — Posted on 2023-09-05
4236 Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in Atypical Teratoid/Rhabdoid Tumors
Metselaar, D. S.; Meel, M. H.; Goulding, J. R.; Waranecki, P.; de Gooijer, M. C.; Breur, M.; Koster, J.; Veldhuijzen van Zanten, S. E.; Bugiani, M.; Wesseling, P.; Kaspers, G. J.; Hulleman, E.
10.1101/2023.09.02.556021 — cancer biology — Posted on 2023-09-05
4239 Deep Batch Active Learning for Drug Discovery
Bailey, M.; Moayedpour, S.; Li, R.; Corrochano-Navarro, A.; Kötter, A.; Kogler-Anele, L.; Riahi, S.; Grebner, C.; Hessler, G.; Matter, H.; Bianciotto, M.; Mas, P.; Bar-Joseph, Z.; Jager, S.
10.1101/2023.07.26.550653 — bioinformatics — Posted on 2023-09-05
4241 Heritable variation in thermoregulation is associated with reproductive success in the world's largest bird
Svensson, E. I.; Schou, M. F.; Melgar, J.; Waller, J. T.; Engelbrecht, A.; Brand, Z.; Schalk, C. C.; Cornwallis, C. K.
10.1101/2022.03.08.483498 — evolutionary biology — Posted on 2023-09-05
4243 The universe is asymmetric, the mouse brain too.
Rivera-Olvera, A.; Houwing, D. J.; Ellegood, J.; Masifi, S.; Martina, S.; Silberfeld, A.; Pourquie, O.; Lerch, J. P.; Francks, C.; Homberg, J. R.; van Heukelum, S.; Grandjean, J.
10.1101/2023.09.01.555907 — neuroscience — Posted on 2023-09-05
4245 Evaluation of trans- and cis-4-fluorogabapentin for brain PET imaging
Zhou, Y.-P.; Normandin, M. D.; Belov, V.; Macdonald-Soccorso, M. T.; Moon, S.-H.; Sun, Y.; El Fakhri, G.; Guehl, N. J.; Brugarolas, P.
10.1101/2023.09.01.555353 — neuroscience — Posted on 2023-09-05
4246 Neural correlates of memory in an immersive spatiotemporal context
Dougherty, M. R.; Chang, W.; Rudoler, J. H.; Katerman, B. S.; Halpern, D.; Bruska, J. P.; Diamond, N.; Kahana, M. J.
10.1101/2022.11.30.518606 — neuroscience — Posted on 2023-09-05
4247 A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria
Faniyan, T. S.; Zhang, X.; Morgan, D. A.; Robles, J.; Bathina, S.; Perry, R. J.; Brookes, P. S.; Rahmouni, K.; Chhabra, K. H.
10.1101/2023.09.01.555894 — physiology — Posted on 2023-09-05
4248 Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice
Hughey, C. C.; Bracy, D. P.; Rome, F. I.; Goelzer, M.; Donahue, E. P.; Viollet, B.; Foretz, M.; Wasserman, D. H.
10.1101/2023.09.01.555935 — physiology — Posted on 2023-09-05
4250 CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling
Rubino, V.; Hueppi, M.; Hoepner, S.; Tortola, L.; Taylor, L.; Keller, I.; Bruggmann, R.; Kronig, M.-N.; Bacher, U. V.; Kopf, M.; Ochsenbein, A.; Riether, C.
10.1101/2023.09.01.555931 — cancer biology — Posted on 2023-09-05
4257 Evaluation of Bayesian Linear Regression Models as a Fine Mapping tool
Shrestha, M.; Bai, Z.; Gholipourshahraki, T.; Hjelholt, A. J.; Kjolby, M.; Rohde, P. D.; Sorensen, P.
10.1101/2023.09.01.555889 — genomics — Posted on 2023-09-05
4260 New tree shrew Parkinson's model: a cost-effective alternative to monkey models
Li, H.; Mei, L.; Nie, X.; Wu, L.; Ren, X.; Lv, L.; Yang, J.; Cao, H.; Wu, J.; Zhang, Y.; Hu, Y.; Wang, W.; Turck, C. W.; Shi, B.; Li, J.; Xu, L.; Hu, X.
10.1101/2023.09.01.555918 — neuroscience — Posted on 2023-09-05
4262 TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling.
Marugan, C.; Ortigosa, B.; Sanz-Gomez, N.; Monfort-Vengut, A.; Bertinetti, C.; Teijo, A.; Gonzalez, M.; Alonso de la Vega, A.; Lallena, M. J.; Moreno-Bueno, G.; de Carcer, G.
10.1101/2023.09.04.556165 — cancer biology — Posted on 2023-09-05
4263 FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail
Majumdar, G.; Liddle, T. A.; Stewart, C.; Marshall, C. J.; Bain, M.; Stevenson, T.
10.1101/2023.03.30.534954 — zoology — Posted on 2023-09-05
4266 PET imaging of fibroblast activation protein alpha (FAP) detects incipient cardiotoxicity due to anthracycline chemotherapy
Lee, C.-H.; Manzo, O.; Rubinelli, L.; Carrasco, S. E.; Cho, S.; Jeitner, T. M.; Babich, J. W.; Di Lorenzo, A.; Kelly, J.
10.1101/2023.09.03.556130 — cancer biology — Posted on 2023-09-05
4272 Claudin-2 limits pancreatitis development through regulating tight junction-controlled pancreatic ductal transport
Kesaraju, S.; Li, Y.; Tracy, M.; Wannemo, K.; Kainov, J.; Rana, N.; Sidahmed, M.; Hyoju, S.; Smith, L.; Matthews, J.; Khalili-Araghi, F.; Rana, M.; Oakes, S.; Shen, L.; Weber, C.
10.1101/2023.09.01.555960 — pathology — Posted on 2023-09-05
4274 Digital spatial profiling of RNA in pancreatic neuroendocrine tumors highlights the distinct profile of alpha-SMA positive stroma and its impact on surrounding tumor cells
Niedra, H.; Peculis, R.; Saksis, R.; Vilisova, S.; Breiksa, A.; Gerina-Berzina, A.; Earl, J.; Ruz-Caracuel, I.; Rosas, M. G.; Rovite, V.
10.1101/2023.09.05.556304 — cancer biology — Posted on 2023-09-05
4275 The SLC1A1/EAAT3 Dicarboxylic Amino Acid Transporter is an Epigenetically Dysregulated Nutrient Carrier that Sustains Oncogenic Metabolic Programs
Grubb, T. M.; Khatun, J.; Matar, S.; Ghandour, F.; Dubasik, N.; Salem, C.; Orlando, D. A.; Guenther, M. G.; Martinez, S. R.; Koochaki, P.; Coker, J. A.; Tang, C.; Reznik, E.; Kotecha, R. R.; Hakimi, A. A.; Abdallah, N.; Weight, C. J.; Choueiri, T. K.; Asara, J. M.; Stauffer, S. R.; Signoretti, S.; Kaelin, W. G.; Chakraborty, A. A.
10.1101/2023.09.04.556240 — cancer biology — Posted on 2023-09-05
4277 An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying translocation RCC.
Ganpat, M.; Morales-Rodriguez, F.; Pham, N.; Lijnzaad, P.; de Souza, T.; Derakhshan, S.; Fumagalli, A.; Zeller, P.; Balwierz, A.; Ayyildiz, D.; van den Heuvel-Eibrink, M. M.; de Krijger, R. R.; van Oudenaarden, A.; Margaritis, T.; Chuva de Sousa Lopes, S. M.; Drost, J.
10.1101/2023.09.01.554626 — cancer biology — Posted on 2023-09-05
4278 Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
Schiroli, G.; Kartha, V. K.; Duarte, F. M.; Kristiansen, T. A.; Mayerhofer, C.; Shrestha, R.; Earl, A.; Hu, Y.; Tay, T.; Rhee, C.; Buenrostro, J.; Scadden, D. T.
10.1101/2023.09.04.556230 — cancer biology — Posted on 2023-09-05
4280 Intervertebral Disc Elastography to Relate Shear Modulus and Relaxometry in Compression and Bending
Davis, Z. R.; Gossett, P. C.; Wilson, R. L.; Kim, W.; Mei, Y.; Butz, K. D.; Emery, N. C.; Nauman, E. A.; Avril, S.; Neu, C. P.; Chan, D. D.
10.1101/2023.09.01.555817 — bioengineering — Posted on 2023-09-05
4282 Metagenomic analysis of individual mosquitos reveals the ecology of insect viruses
Pan, Y.-f.; Zhao, H.; Gou, Q.-y.; Shi, P.-b.; Tian, J.-h.; Feng, Y.; Li, K.; Yang, W.-h.; Wu, D.; Tang, G.; Zhang, B.; Ren, Z.; Peng, S.; Luo, G.-y.; Le, S.-j.; Xin, G.-y.; Wang, J.; Hou, X.; Peng, M.-w.; Kong, J.-b.; Chen, X.-x.; Yang, C.-h.; Mei, S.-q.; Liao, Y.-q.; Cheng, J.-x.; Wang, J.; Chaolemen, ; Wu, Y.-h.; Wang, J.-b.; An, T.; Huang, X.; Eden, J.-S.; Li, J.; Guo, D.; Liang, G.; Jin, X.; Holmes, E. C.; Li, B.; Wang, D.; Li, J.; Wu, W.-c.; Shi, M.
10.1101/2023.08.28.555221 — ecology — Posted on 2023-09-05
4286 Distinct states of nucleolar stress induced by anti-cancer drugs
Potapova, T. A.; Unruh, J. R.; Conkright-Fincham, J. J.; Banks, C. A. S.; Florens, L.; Schneider, D. A.; Gerton, J. L.
10.1101/2022.11.18.517150 — cell biology — Posted on 2023-09-05
4287 Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development
Yue, T.; Guo, Y.; Qi, X.; Zheng, W.; Zhang, H.; Wang, B.; Zhou, B.; Zeng, X.; NA, O.; He, Y.; Su, B.
10.1101/2023.05.24.542081 — evolutionary biology — Posted on 2023-09-05
4292 Mechanosensing through talin 1 contributes to tissue mechanical homeostasis
Chanduri, M. V.; Kumar, A.; Weiss, D.; Emuna, N.; Barsukov, I.; Shi, M.; Tanaka, K.; Wang, X.; Datye, A.; Kanyo, J.; Collin, F.; Lam, T.; Schwarz, U. D.; Bai, S.; Nottoli, T.; Goult, B. T.; Humphrey, J. T.; Schwartz, M. A.
10.1101/2023.09.03.556084 — cell biology — Posted on 2023-09-05
4293 Structure of Native Chromatin Fibres Revealed by Cryo-ET in situ
Hou, Z.; Nightingale, F.; Zhu, Y.; MacGregor-Chatwin, C.; Zhang, P.
10.1101/2023.09.03.556082 — cell biology — Posted on 2023-09-05
4294 RNA binding proteins and glycoRNAs form domains on the cell surface for cell penetrating peptide entry
Perr, J.; Langen, A.; Almahayni, K.; Nestola, G.; Chai, P.; Lebedenko, C.; Volk, R.; Caldwell, R.; Spiekermann, M.; Hemberger, H.; Bisaria, N.; Tzelepis, K.; Calo, E.; Mockl, L.; Zaro, B.; Flynn, R. A.
10.1101/2023.09.04.556039 — cell biology — Posted on 2023-09-05
4297 Penile cavernous sinusoids are Prox1-positive hybrid vessels
Schnabellehner, S.; Kraft, M.; Schoofs, H.; Ortsater, H.; Makinen, T.
10.1101/2023.09.01.555933 — cell biology — Posted on 2023-09-05
4299 Permanent Neonatal Diabetes-causing Insulin Mutations have Dominant Effects on Proinsulin Processing and Beta Cell Identity
Zhang, Y.; Sui, L.; Du, Q.; Haataja, L.; Yin, Y.; Viola, R.; Xu, S.; Nielsson, C. U.; Leibel, R. L.; Barbetti, F.; Arvan, P.; Egli, D.
10.1101/2023.09.01.555839 — cell biology — Posted on 2023-09-05
4300 The Effects of Aging on Rod Bipolar Cell Ribbon Synapses
Shrestha, A. P.; Rameshkumar, N.; Boff, J. M.; Rajmanna, R.; Chandrasegaran, T.; Zenisek, D.; Vaithianathan, T.
10.1101/2023.09.01.555825 — neuroscience — Posted on 2023-09-05
4308 Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase.
Taylor, A.; Zhang, S.; Johannissen, L.; Sakuma, M.; Phillips, R.; Green, A.; Hay, S.; Heyes, D.; Scrutton, N.
10.1101/2023.09.04.556209 — biochemistry — Posted on 2023-09-04
4309 Eta-secretase-like processing of the amyloid precursor protein (APP) by RHBDL4
Penalva, Y. C. M.; Paschkowsky, S.; Recinto, S. J.; Duchesne, A.; Levet, C.; Charron, F.; Freeman, M.; McKinney, R. A.; Trempe, J.-F.; Munter, L. M.
10.1101/2023.09.04.555897 — biochemistry — Posted on 2023-09-04
4310 SLP2 coordinates MICOS assembly and cristae morphogenesis via MIC13 and YME1L
Naha, R.; Strohm, R.; Urbach, J.; Wittig, I.; Reichert, A. S.; Kondadi, A. K.; Anand, R.
10.1101/2023.09.04.556207 — biochemistry — Posted on 2023-09-04
4311 A pan-MHC reference graph with 246 fully contiguous phased sequences
Huijse, L.; Adams, S. M.; Burton, J. N.; David, J. K.; Julian, R. S.; Meshulam-Simon, G.; Mickalide, H.; Tafesse, B. D.; Calonga-Solis, V.; Wolf, I. R.; Morrison, A. J.; Augusto, D. G.; Endlich, S.
10.1101/2023.09.01.555813 — genomics — Posted on 2023-09-04
4312 The RecBC complex protects the nascent DNA in the presence of single-stranded DNA gaps
Philippin, G.; Chrabaszcz, E.; Iturralde, M.; Modesti, M.; Pages, V.; Laureti, L.
10.1101/2023.09.04.556180 — molecular biology — Posted on 2023-09-04
4317 A Far-Red Fluorescent Probe to Visualize Staphylococcus aureus in Patient Samples
Jantarug, K.; Tripathi, V.; Morin, B.; Iizuka, A.; Kuehl, R.; Morgenstern, M.; Clauss, M.; Khanna, N.; Bumann, D.; Rivera-Fuentes, P.
10.1101/2023.09.04.556223 — microbiology — Posted on 2023-09-04
4320 Investigating the genetic control of plant development under speed breeding conditions
Rossi, N.; Powell, W.; Mackay, I.; Hickey, L.; Maurer, A.; Pillen, K.; Halliday, K.; Sharma, R.
10.1101/2023.09.04.555916 — plant biology — Posted on 2023-09-04
4321 Rho of plant GTPases with geranylgeranylation motif modulate monoterpene indole alkaloid biosynthesis in Catharanthus roseus
Bomzan, D. P.; Sharma, A.; Cruz, P. L.; Carqueijeiro, I.; Bellenger, L.; Rai, A.; Thippesh, A. K.; C, V. S.; Parihar, D.; Ducos, E.; Courdavault, V.; Nagegowda, D. A.
10.1101/2023.09.04.554920 — plant biology — Posted on 2023-09-04
4322 Cellular taxonomy of the preleukemic bone marrow niche of acute myeloid leukemia
Goda, C.; Kulkarni, R.; Rudich, A.; Karunasiri, M.; Balcioglu, O.; Al-Marrawi, Y.; Korn, E.; Kanna, S.; Garfinkle, E. A. R.; Mundy-Bosse, B.; Zhang, B.; Marcucci, G.; Mardis, E. R.; Garzon, R.; Miller, K. E.; Dorrance, A. M.
10.1101/2023.09.01.553259 — cancer biology — Posted on 2023-09-04
4327 Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains
Guo, L.; Mann, J. R.; Mauna, J. C.; Copley, K. E.; Wang, H.; Rubien, J. D.; Odeh, H. M.; Lin, J.; Lee, B. L.; Ganser, L.; Robinson, E.; Kim, K. M.; Murthy, A. C.; Paul, T.; Portz, B.; Gleixner, A. M.; Diaz, Z.; Carey, J. L.; Smirnov, A.; Padilla, G.; Lavorando, E.; Espy, C.; Shang, Y.; Huang, E. J.; Chesi, A.; Fawzi, N. L.; Myong, S.; Donnelly, C. J.; Shorter, J.
10.1101/2023.09.04.555754 — biochemistry — Posted on 2023-09-04
4331 Kin selection underpins family dynamics in rural China
He, Q.-Q.; Wang, M.-Y.; Wu, J.-J.; Feng, T.-J.; Zheng, X.-D.; Yu, J.-R.; Tang, S.-H.; Deng, L.-L.; Fu, C.; Mace, R.; Tao, Y.; Ji, T.
10.1101/2023.09.04.552901 — evolutionary biology — Posted on 2023-09-04
4333 Deep Whole-Genome Resequencing of Marek's Disease Virus Strains Reveals Intrastrain Variation
Ortigas-Vasquez, A.; Pandey, U.; Renner, D. W.; Bowen, C. D.; Baigent, S.; Dunn, J.; Cheng, H.; Yao, Y.; Read, A. F.; Nair, V.; Kennedy, D. A.; Szpara, M. L.
10.1101/2023.09.04.556264 — microbiology — Posted on 2023-09-04
4334 Examining the molecular clock hypothesis for the contemporary evolution of the rabies virus
Durrant, R.; Cobbold, C.; Brunker, K.; Campbell, K.; Dushoff, J.; Ferguson, E.; Jaswant, G.; Lugelo, A.; Lushasi, K.; Sikana, L.; Hampson, K.
10.1101/2023.09.04.556169 — microbiology — Posted on 2023-09-04
4335 "Candidatus Siderophilus nitratireducens": a psychrophilic, nap-dependent nitrate-reducing iron oxidizer within the new order Siderophiliales
Corbera-Rubio, F.; Stouten, G. R.; Bruins, J.; Dost, S. F.; Merkel, A. Y.; Muller, S.; van Loosdrecht, M. C. M.; van Halem, D.; Laureni, M.
10.1101/2023.09.04.556225 — microbiology — Posted on 2023-09-04
4339 Structural flexibility dominates over binding strength for supramolecular crystallinity
Caroprese, V.; Tekin, C.; Cencen, V.; Mosayebi, M.; Liverpool, T.; Woolfson, D.; Fantner, G. E.; Bastings, M. M. C.
10.1101/2023.09.04.556250 — bioengineering — Posted on 2023-09-04
4340 A Stapled Peptide Inhibitor of METTL3-METTL14 for Cancer Therapy
Li, Z.; Feng, Y.; Han, H.; Jiang, X.; Chen, W.; Ma, X.; Mei, Y.; Yan, X.; Yin, P.; Yuan, D.; Zhang, D.; Shi, J.
10.1101/2023.09.04.556216 — biochemistry — Posted on 2023-09-04
4341 Demographic and ecological drivers of infectome diversity in companion cats
Sun, Y.; Xing, J.; Xu, S.; Li, Y.; Gao, H.; Cheng, S.; Dong, J.; Zhang, T.; Lu, G.; Baele, G.; Zhang, G.
10.1101/2023.09.01.555855 — evolutionary biology — Posted on 2023-09-04
4344 Dietary road salt and monarch butterflies: minimal effects on larval growth, immunity, wing coloration, and migration to Mexico
Hund, A. K.; Mitchell, T. S.; Ramirez, I.; Zambre, A.; Hagg, L.; Stene, A.; Porter, K.; Carper, A.; Agnew, L.; Shephard, A.; Kobiela, M.; Oberhauser, K.; Taylor, O. R.; Snell-Rood, E.
10.1101/2023.09.04.554310 — ecology — Posted on 2023-09-04
4346 Neutralization of SARS-CoV-2 EG.5/EG.5.1 by sera from ZF2001 RBD-dimer and its next-generation vaccines
An, Y.; Zhou, X.; Tao, L.; Xie, H.; Yang, C.; Li, D.; Wang, R.; Hu, H.; Liu, K.; Dai, L.; Xu, K.; Gao, G. F.
10.1101/2023.09.02.556038 — immunology — Posted on 2023-09-04
4347 Antigenicity and infectivity characterization of SARS-CoV-2 BA.2.86
Yang, S.; Yu, Y.; Jian, F.; Song, W.; Yisimayi, A.; Chen, X.; Xu, Y.; Wang, P.; Yu, L.; Wang, J.; Niu, X.; Wang, J.; Xiao, T.; An, R.; Wang, Y.; Gu, Q.; Shao, F.; Jin, R.; Shen, Z.; Wang, Y.; Cao, Y. R.
10.1101/2023.09.01.555815 — immunology — Posted on 2023-09-04
4351 Meisoindigo: An Effective Inhibitor of SARS-CoV-2 Main Protease Revealed by Yeast System
Grabinski, W.; Kicinska, A.; Kosicka, E.; Baranek-Grabinska, M.; Hejenkowska, E. D.; Budzik, J.; Sliska, P.; Sliwinska, W.; Karachitos, A.
10.1101/2023.09.03.555867 — pharmacology and toxicology — Posted on 2023-09-04
4352 Glioblastoma is spatially organized by neurodevelopmental programs and a glial-like wound healing response
Mossi Albiach, A.; Janusauskas, J.; Kapustova, I.; Kvedaraite, E.; Codeluppi, S.; Munting, J. B.; Borm, L. E.; Kjaer Jacobsen, J.; Shamikh, A.; Persson, O.; Linnarsson, S.
10.1101/2023.09.01.555882 — cancer biology — Posted on 2023-09-04
4356 Comparative pangenomic insights into the distinct evolution of virulence factors among grapevine trunk pathogens
Garcia, J.; Morales-Cruz, A.; Cochetel, N.; Minio, A.; Figueroa-Balderas, R.; Rolshausen, P.; Baumgartner, K.; Cantu, D.
10.1101/2023.09.03.555958 — genomics — Posted on 2023-09-04
4358 Sensitivity of BA.2.86 to prevailing neutralising antibody responses
Sheward, D. J.; Yang, Y.; Westerberg, M.; Öling, S.; Muschiol, S.; Sato, K.; Peacock, T. P.; Karlsson Hedestam, G. B.; Albert, J.; Murrell, B.
10.1101/2023.09.02.556033 — immunology — Posted on 2023-09-04
4362 Borrelia burgdorferi PlzA is a cyclic-di-GMP dependent DNA- and RNA-binding protein
Jusufovic, N.; Krusensjerna, A. C.; Savage, C.; Saylor, T. C.; Brissette, C. A.; Zueckert, W. R.; Schlax, P.; MOTALEB, M. A. R.; Stevenson, B.
10.1101/2023.01.30.526351 — microbiology — Posted on 2023-09-04
4366 SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy
Dembitz, V.; Lawson, H.; Burt, R.; Philippe, C.; James, S. C.; Atkinson, S.; Durko, J.; Wang, L. M.; Campos, J.; Magee, A. M.; Woodley, K.; Austin, M. J.; Rio-Machin, A.; Casado-Izquierdo, P.; Bewicke-Copley, F.; Rodriguez, G.; Pereira, D.; Oudejans, L.; Boet, E.; von Kriegsheim, A.; Schwaller, J.; Finch, A. J.; Pate, B.; Sarry, J.-E.; Tamburini, J.; Schuringa, J. J.; Hazlehurst, L.; Copland, J. A.; Yuneva, M.; Peck, B.; Cutillas, P.; Fitzgibbon, J.; Rouault-Pierre, K.; Kranc, K.; Gallipoli, P.
10.1101/2023.08.02.551656 — cancer biology — Posted on 2023-09-04
4367 Adsorbing DNA to mica by cations: Influence of the valency and ion type
Ibrahim, M.; Wenzel, C.; Lallemang, M.; Balzer, B. N.; Schwierz, N.
10.1101/2023.06.30.547224 — biophysics — Posted on 2023-09-04
4368 Matrix Softening Controls Stretch-Induced Cellular Memory and Fibroblast Activation
Hong, Y.; Peng, X.; Yu, H.; Jafari, M.; Shakiba, D.; Huang, Y.; Qu, C.; Melika, E.; Tawadros, A.; Mujahid, A.; Sandler, J.; Pryse, K.; Sacks, J.; Elson, E.; Genin, G.; Alisafaei, F.
10.1101/2022.10.12.511903 — biophysics — Posted on 2023-09-04
4369 Imputation of label-free quantitative mass spectrometry-based proteomics data using self supervised deep learning
Webel, H.; Niu, L.; Bach Nielsen, A.; Locard-Paulet, M.; Mann, M.; Juhl Jensen, L.; Rasmussen, S.
10.1101/2023.01.12.523792 — bioinformatics — Posted on 2023-09-04
4370 Cryo-EM of soft-landed β-galactosidase: Gas-phase and native structures are remarkably similar
Esser, T. K.; Boehning, J.; Onur, A.; Chinthapalli, D. K.; Eriksson, L.; Grabarics, M.; Fremdling, P.; Konijnenberg, A.; Makarov, A. A.; Botman, A.; Peter, C.; Benesch, J. L. P.; Robinson, C. V.; Gault, J.; Baker, L.; Bharat, T. A. M.; Rauschenbach, S.
10.1101/2023.08.17.553673 — biochemistry — Posted on 2023-09-04
4371 The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes
Raguseo, F.; Huyghebaert, A.; Li, J.; Balendra, R.; Petric Howe, m.; Wang, Y.; Vadukul, D. M.; Tanase, D.; Maher, T. E.; Malouf, L.; Rubio Sanchez, R.; Aprile, F. A.; Elani, Y.; Patani, R.; Di Michele, L.; Di Antonio, M.
10.1101/2023.01.31.526399 — biochemistry — Posted on 2023-09-04
4372 CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
Wang, B.; Liang, Z.; Tan, T.; Zhang, M.; Jiang, Y.; Shang, Y.; Gao, X.; Song, S.; Wang, R.; Chen, H.; Liu, J.; Li, J.; Ren, Y.; Liu, P.
10.1101/2023.02.15.528649 — cell biology — Posted on 2023-09-04
4373 Reference materials for SARS-CoV-2 molecular diagnostic: validation of encapsulated synthetic RNAs for room temperature storage and shipping
Colotte, M.; Luis, A.; Bonnet, J.; Coudy, D.; Tuffet, S.; Robene, I.; Fenelon, B.; Jouen, E.; Leveque, N.; Alain, S.; Plumelle, D.; Tumiotto, C.; Busson, L.; Lafon, M.-E.
10.1101/2023.08.28.555008 — molecular biology — Posted on 2023-09-04
4379 Comparing mouse and human cingulate cortex organization using functional connectivity
van Hout, A. T. B.; van Heukelum, S.; Rushworth, M. F. S.; Grandjean, J.; Mars, R. B.
10.1101/2023.09.04.556193 — neuroscience — Posted on 2023-09-04
4382 Oligodendrocyte precursor cells engulf synapses in a model of the developing human forebrain
Gkogka, A.; Malwade, S.; Koskuvi, M.; Bose, R.; Ceccatelli, S.; Koistinaho, J.; Tiihonen, J.; Schalling, M.; S, S.; Sellgren-Majkowitz, C.
10.1101/2023.09.04.556176 — neuroscience — Posted on 2023-09-04
4384 Comprehensive analysis of A-type lamin tail region for repairing the nuclear lamina
Kono, Y.; Pack, C.-G.; Ichikawa, T.; Komatsubara, A.; Adam, S. A.; Rolas, L.; Nourshargh, S.; Medalia, O.; Goldman, R. D.; Fukuma, T.; Kimura, H.; Shimi, T.
10.1101/2023.09.02.555826 — cell biology — Posted on 2023-09-04
4385 Human subcutaneous and visceral adipocyte atlases uncover classical and specialized adipocytes and depot-specific patterns
Lazarescu, O.; Ziv Agam, M.; Haim, Y.; Hekselman, I.; Jubran, J.; Shneyour, A.; Kitsberg, D.; Levin, L.; Liberty, I. F.; Yoel, U.; Dukhno, O.; Adam, M.; Korner, A.; Murphy, R.; Bluher, M.; Habib, N.; Rudich, A.; Yeger-Lotem, E.
10.1101/2023.09.04.555678 — systems biology — Posted on 2023-09-04
4386 heterotypic interaction promotes asymmetric division of human hematopoietic stem and progenitor cells
Candelas, A.; Vianay, B.; Gelin, M.; Faivre, L.; Larghero, J.; Blanchoin, L.; Thery, M.; Brunet, S.
10.1101/2023.08.31.555706 — cell biology — Posted on 2023-09-04
4388 Nanopore adaptive sampling effectively enriches bacterial plasmids
Ulrich, J.-U.; Epping, L.; Pilz, T.; Walther, B.; Stingl, K.; Semmler, T.; Renard, B. Y.
10.1101/2022.10.03.510741 — bioinformatics — Posted on 2023-09-04
4389 On growth and form of the mammary gland: Mesenchyme instructs growth while epithelium directs branching
Lan, Q.; Trela, E.; Lindstrom, R.; Satta, J.; Kaczynska, B.; Christensen, M. M.; Holzenberger, M.; Jernvall, J.; Mikkola, M. L.
10.1101/2023.04.24.538064 — developmental biology — Posted on 2023-09-04
4390 A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
Lim, K.; Rutherford, E. N.; Sun, D.; Van den Boomen, D. J.; Edgar, J. R.; Bang, J.; Matesic, L. E.; Lee, J.-H.; Lehner, P. J.; Marciniak, S. J.; Rawlins, E. L.; Dickens, J. A.
10.1101/2023.08.30.555522 — cell biology — Posted on 2023-09-04
4391 Pre-existing tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia
Mann, Z.; Lim, F.; Verma, S.; Nanavati, B. N.; Davies, J. M.; Begun, J.; Hardeman, E. C.; Gunning, P. W.; Subramanyam, D.; Yap, A. S.; Duszyc, K.
10.1101/2023.08.31.555652 — cell biology — Posted on 2023-09-04
4392 Brain map of aging-induced alterations in membrane ganglioside pattern
Jha, D.; Dovrtelova, G.; Telensky, P.; Olkowicz, S.; Coufalikova, K.; Opalka, L.; Kubicek, K.; Becvarova, B.; Hajek, R.; Belaskova, S.; Klanova, J.; Hampl, A.; Damborsky, J.; Spacil, Z.
10.1101/2023.08.30.555520 — neuroscience — Posted on 2023-09-04
4398 TIPRL1 and its ATM-dependent phosphorylation promote radiotherapy resistance in head and neck cancer
Janssens, V.; Cokelaere, C.; Dok, R.; Cortesi, E.; Zhao, P.; Sablina, A.; Nuyts, S.; Derua, R.
10.1101/2023.08.30.555468 — cancer biology — Posted on 2023-09-04
4399 ALK signalling primes the DNA damage response sensitizing ALK-driven neuroblastoma to ATR inhibition
Borenäs, M.; Umapathy, G.; Lind, D. E.; Lai, W.-Y.; Guan, J.; Johansson, J.; Jennische, E.; Schmidt, A.; Kurhe, Y. V.; Gabre, J. L.; Aniszewska, A.; Strömberg, A.; Bemark, M.; Hall, M. N.; Van den Eynden, J.; Hallberg, B.; Palmer, R. H.
10.1101/2023.08.30.555570 — cancer biology — Posted on 2023-09-04
4400 CellsFromSpace: A versatile tool for spatial transcriptomic data analysis with reference-free deconvolution and guided cell type/activity annotation
Thuilliez, C.; Moquin-Beaudry, G.; Khneisser, p.; Marques Da Costa, M. E.; Karkar, S.; Boudhouche, H.; Drubay, D.; Audinot, B.; Geoerger, B.; Scoazec, J.-Y.; Gaspar, N.; Marchais, A.
10.1101/2023.08.30.555558 — bioinformatics — Posted on 2023-09-04
4402 The Soil Food Web Ontology: aligning trophic groups, processes, resources, and dietary traits to support food-web research
Le Guillarme, N.; Hedde, M.; Potapov, A.; Martinez-Munoz, C. A.; Berg, M. P.; Briones, M. J. I.; Calderon-Sanou, I.; Degrune, F.; Hohberg, K.; Martinez-Almoyna, C.; Pey, B.; Russell, D.; Thuiller, W.
10.1101/2023.02.03.526812 — ecology — Posted on 2023-09-04
4404 Weak neuronal glycolysis sustains cognition and organismal fitness
Jimenez-Blasco, D.; Agulla, J.; Lapresa, R.; Garcia-Macia, M.; Bobo-Jimenez, V.; Garcia-Rodriguez, D.; Manjarres-Raza, I.; Fernandez, E.; Jeanson, Y.; Khoury, S.; Portais, J.-C.; Padro, D.; Ramos-Cabrer, P.; Carmeliet, P.; Almeida, A.; Bolanos, J. P.
10.1101/2023.09.02.556016 — cell biology — Posted on 2023-09-04
4407 Exploiting fluctuations in gene expression to detect causal interactions between genes
Joly-Smith, E.; Talpur, M. M.; Allard, P.; Papazotos, F.; Potvin-Trottier, L.; Hilfinger, A.
10.1101/2023.09.01.555799 — systems biology — Posted on 2023-09-04
4408 Enhanced metabolic detoxification is associated with fluroxypyr resistance in Bassia scoparia
Todd, O. E.; Patterson, E.; Westra, E. P.; Nissen, S. J.; Simoes Araujo, A. L.; Kramer, W. B.; Dayan, F. E.; Gaines, T. A.
10.1101/2023.08.29.554743 — plant biology — Posted on 2023-09-04
4409 Exact distribution of the quantal content in synaptic transmission
Rijal, K.; Müller, N. I. C.; Friauf, E.; Singh, A.; Prasad, A.; Das, D.
10.1101/2022.12.28.522121 — biophysics — Posted on 2023-09-04
4414 Multi-day Neuron Tracking in High Density Electrophysiology Recordings using EMD
Yuan, A. X.; Colonell, J. I.; Lebedeva, A.; Okun, M.; Charles, A.; Harris, T. D.
10.1101/2023.08.03.551724 — neuroscience — Posted on 2023-09-03
4417 Structural Adaptation of Fungal Cell Wall in Hypersaline Environment
Fernando, L. D.; Perez-Llano, Y.; Dickwella Widanage, M. C.; Jacob, A.; Martinez-Avila, L.; Lipton, A. S.; Gunde-Cimerman, N.; Latge, J.-P.; Batista-Garcia, R. A.; Wang, T.
10.1101/2023.04.15.537024 — biophysics — Posted on 2023-09-03
4420 AlphaFold2 can predict single-mutation effects
Mcbride, J. M.; Reinharz, V.; Polev, K.; Grzybowski, B. A.; Tlusty, T.
10.1101/2022.04.14.488301 — biochemistry — Posted on 2023-09-03
4421 Weak neuronal glycolysis sustains cognition and organismal fitness
Jimenez-Blasco, D.; Agulla, J.; Lapresa, R.; Garcia-Macia, M.; Bobo-Jimenez, V.; Garcia-Rodriguez, D.; Manjarres-Raza, I.; Fernandez, E.; Jeanson, Y.; Khoury, S.; Portais, J.-C.; Padro, D.; Ramos-Cabrer, P.; Carmeliet, P.; Almeida, A.; Bolanos, J. P.
10.1101/2023.09.02.556016 — cell biology — Posted on 2023-09-03
4424 The effect of dopamine D2 receptor blockade on human motor skill learning
Taylor, E. M.; Curtin, D.; Chong, T. T.-J.; Bellgrove, M. A.; Coxon, J. P.
10.1101/2023.09.01.556003 — neuroscience — Posted on 2023-09-03
4427 Inter-regional delays fluctuate in the human cerebral cortex
Moon, J.-Y.; Muesch, K.; Schroeder, C.; Valiante, T.; Honey, C.
10.1101/2022.06.01.494224 — neuroscience — Posted on 2023-09-03
4428 Hydrogen Sulfide Coordinates Glucose Metabolism Switch through Destabilizing Tetrameric Pyruvate Kinase M2
Wang, R.-H.; Chen, P.-R.; Chen, Y.-T.; Chen, Y.-C.; Chu, Y.-H.; Chien, C.-C.; Chien, P.-C.; Lo, S.-Y.; Wang, Z.-L.; Tsou, M.-C.; Chen, S.-Y.; Chiu, G.-S.; Chen, W.-L.; Wu, Y.-H.; Wang, L.; Wang, W.-C.; Lin, S.-Y.; Kung, H.-J.; Wang, L.-H.; Cheng, H.-C.; Lin, K.-T.
10.1101/2023.09.02.555034 — cancer biology — Posted on 2023-09-03
4430 Human milk extracellular vesicles survive neonatal digestion in vivo to be absorbed by neonatal enteroids
Zhang, Y.; Kuhn, M.; Yung, C.; Armstrong, R. J.; Olyaei, A.; Aloia, M.; Scottoline, B.; Andres, S. F.
10.1101/2023.09.03.556067 — molecular biology — Posted on 2023-09-03
4433 Protein coopted from a phage restriction system dictates orthogonal cell division plane selection in Staphylococcus aureus
Ramos-Leon, F.; Anjuwon-Foster, B. R.; Anantharaman, V.; Ferreira, C. N.; Ibrahim, A. M.; Tai, C.-H.; Missiakas, D. M.; Camberg, J.; Aravind, L.; Ramamurthi, K. S.
10.1101/2023.09.03.556088 — microbiology — Posted on 2023-09-03
4435 Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance
Watt, H. J.; Chawla, A. S.; Lamoliatte, F.; Pryde, S.; Knatko, E.; Rasmussen, K. D.; Bending, D.; Swamy, M.
10.1101/2023.09.01.555859 — immunology — Posted on 2023-09-03
4437 Dopamine receptor-expressing neurons are differently distributed throughout layers of the motor cortex to control dexterity
Cieslak, P. E.; Drabik, S.; Gugula, A.; Trenk, A.; Gorkowska, M.; Przybylska, K.; Szumiec, L.; Kreiner, G.; Parkitna, J. R.; Blasiak, A.
10.1101/2023.08.31.555724 — neuroscience — Posted on 2023-09-03
4438 Genetically mediated associations between chronotype and neuroimaging phenotypes in the UK Biobank: a Mendelian randomisation study
Williams, J. A.; Russ, D. R.; Bravo-Merodio, L.; Gkoutos, G.; Bellgrove, M. A.; Bagshaw, A. P.; Chechlacz, M.
10.1101/2023.08.31.555801 — neuroscience — Posted on 2023-09-03
4440 Unilateral hippocampal stroke in freely behaving mice reveals sex differences in contralesional spreading depolarization and associated behavior
Boyce, A. K.; Fouad, Y.; Gom, R.; Martins-Silva, C.; Molina, L.; Fuzesi, T.; Ens, C.; Nicola, W.; Teskey, G. C.; Thompson, R. J.
10.1101/2023.08.31.555814 — neuroscience — Posted on 2023-09-03
4442 Is the neuropeptide PEN a ligand of GPR83?
Giesecke, Y.; Asimi, V.; Stulberg, V.; Kleinau, G.; Scheerer, P.; Koksch, B.; Groetzinger, C.
10.1101/2023.08.31.555736 — pharmacology and toxicology — Posted on 2023-09-03
4443 Longitudinal Micro-Computed Tomography Detects Onset and Progression of Pulmonary Fibrosis in Conditional Nedd4-2 Deficient Mice
Leitz, D. H. W.; Konietzke, P.; Wagner, W.; Mertiny, M.; Benke, C.; Schneider, T.; Stiller, W.; Kauczor, H.-U.; Mall, M. A.; Duerr, J.; Wielpuetz, M. O.
10.1101/2023.08.31.555725 — pathology — Posted on 2023-09-03
4444 The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability
Ravn-Boess, N.; Roy, N.; Hattori, T.; Bready, D.; Donaldson, H.; Lawson, C.; Lapierre, C.; Korman, A.; Rodrick, T.; Liu, E.; Frenster, J. D.; Stephan, G.; Wilcox, J.; Corrado, A. D.; Cai, J.; Ronnen, R.; Wang, S.; Haddock, S.; Sabio Ortiz, J.; Mishkit, O.; Khodadadi-Jamayran, A.; Tsirigos, A.; Fenyo, D.; Zagzag, D.; Perna, F.; Jones, D. R.; Possemato, R.; Koide, A.; Koide, S.; Park, C. Y.; Placantonakis, D. G.
10.1101/2023.08.31.555733 — cancer biology — Posted on 2023-09-03
4445 Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker
Martins, T. A.; Tatari, N.; Kaymak, D.; Hogan, S.; Bartoszek, E. M.; Wieboldt, R.; Ritz, M.-F.; Buck, A.; McDaid, M.; Gerber, A.; Beshirova, A.; Etter, M. M.; Heider, A.; Shekarian, T.; Mohamed, H.; Schmassmann, P.; Abel, I.; Mariani, L.; Guzman, R.; Boulay, J.-L.; Snijder, B.; Weiss, T.; Laubli, H.; Hutter, G.
10.1101/2023.08.31.555122 — cancer biology — Posted on 2023-09-03
4446 Inhibition of CREB binding and function with a dual-targeting ligand
Liu, Y.; Joy, S. T.; Henley, M. J.; Yates, J. A.; Merajver, S. D.; Mapp, A. K.
10.1101/2023.09.03.556086 — biochemistry — Posted on 2023-09-03
4447 Apolipoprotein-E transforms intracellular Amyloid-β oligomers to a more toxic state
Dey, A.; Verma, A.; Bhaskar, U.; Sarkar, B.; Kallianpur, M.; Visvakarma, V.; Das, A. K.; Garai, K.; Mukherjee, O.; Ishii, K.; Tahara, T.; Maiti, S.
10.1101/2023.09.03.556061 — biochemistry — Posted on 2023-09-03
4448 Advances in genomic characterization of Urochloa humidicola: exploring polyploid inheritance and apomixis
Moraes, A. d. C. L.; Mollinari, M.; Ferreira, R. U.; Aono, A. H.; Lara, L. A. d. C.; Pessoa-Filho, M.; Barrios, S. C. L.; Garcia, A. A. F.; do Valle, C. B.; de Souza, A. P.; Vigna, B. B. Z.
10.1101/2023.08.31.555743 — genomics — Posted on 2023-09-03
4449 Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states
Balasubramanian, R.; Kizhatil, K.; Li, T.; Tolman, N.; Bhandari, A.; Clark, G.; Bupp-Chickering, V.; Zhou, S.; Peregrin, J.; Simon, M.; Montgomery, C.; Qian, J.; John, S.
10.1101/2023.08.31.555823 — genomics — Posted on 2023-09-03
4454 CoSMIC - A hybrid approach for large-scale, high-resolution microbial profiling of novel niches
Knafo, M.; Rezenman, S.; Idan, T.; Elgart, M.; Dagan, S.; Reich, Z.; Kapon, R.; Sade, D.; Shental, N.
10.1101/2023.09.03.556087 — molecular biology — Posted on 2023-09-03
4455 Interference Requirements of Type III CRISPR-Cas Systems from Thermus thermophilus
Karneyeva, K.; Kolesnik, M.; Livenskyi, A.; Zgoda, V.; Zubarev, V.; Trofimova, A.; Artamonova, D.; Ispolatov, Y.; Severinov, K.
10.1101/2023.09.03.556089 — microbiology — Posted on 2023-09-03
4456 Single-B cell analysis correlates high-lactate secretion with stress and increased apoptosis
Bucheli, O. T. M.; Rodrigues, D.; Portmann, K.; Linder, A.; Thoma, M.; Halin, C.; Eyer, K.
10.1101/2023.09.01.555863 — immunology — Posted on 2023-09-03
4460 Molecular evolution of male reproduction across species with highly divergent sperm morphology in diverse murine rodents
Kopania, E. E. K.; Thomas, G. W. C.; Hutter, C. R.; Mortimer, S. M. E.; Callahan, C. M.; Roycroft, E.; Achmadi, A. S.; Breed, W. G.; Clark, N. L.; Esselstyn, J. A.; Rowe, K. C.; Good, J. M.
10.1101/2023.08.30.555585 — evolutionary biology — Posted on 2023-09-03
4461 Cell wall fluidization by mechano-endopeptidases sets up a turgor-mediated volumetric pacemaker
Mukherjee, A.; Huang, Y.; Oh, S.; Sanchez, C.; Chang, Y.-F.; Liu, X.; Bradshaw, G. A.; Benites, N. C.; Paulsson, J.; Kirschner, M. W.; Sung, Y.; Elgeti, J.; Basan, M.
10.1101/2023.08.31.555748 — microbiology — Posted on 2023-09-03
4462 A Mechanistic Insight into Sources of Error of Visual Working Memory in Multiple Sclerosis
Motahharynia, A.; Pourmohammadi, A.; Adibi, A.; Shaygannejad, V.; Ashtari, F.; Adibi, I.; Sanayei, M.
10.1101/2023.02.20.529229 — neuroscience — Posted on 2023-09-03
4465 Tick hemocytes have pleiotropic roles in microbial infection and arthropod fitness
Rolandelli, A.; Laukaitis-Yousey, H.; Bogale, H.; Singh, N.; Samaddar, S.; ONeal, A.; Ferraz, C.; Butnaru, M.; Mameli, E.; Xia, B.; Mendes, M. T.; Butler, L. R.; Marnin, L.; Cabrera Paz, F.; Valencia, L.; Rana, V.; Skerry, C.; Pal, U.; Mohr, S.; Perrimon, N.; Serre, D.; Pedra, J.
10.1101/2023.08.31.555785 — immunology — Posted on 2023-09-03
4469 Respective contribution of Appl to mushroom body axon growth and long-term memory in Drosophila
Marquilly, C.; Boulanger, A.; Busto, G. U.; Pasquer, L.; Zinzen, R. P.; Hassan, B. A.; Fradkin, L. G.; Preat, T.; Dura, J.-M.
10.1101/2023.09.01.555727 — neuroscience — Posted on 2023-09-03
4472 Urban living can rescue Darwin's finches from the lethal effects of invasive vampire flies
Knutie, S. A.; Webster, C. N.; Vaziri, G. J.; Albert, L.; Harvey, J. A.; LaRue, M.; Verrett, T. B.; Soldo, A.; Koop, J. A. H.; Chaves, J. A.; Wegrzyn, J. L.
10.1101/2023.03.06.531275 — ecology — Posted on 2023-09-03
4474 Flexible and abstract neural representations of structural knowledge
Mark, S.; baram, a.; Schwartenbeck, p.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.
10.1101/2023.08.31.555760 — neuroscience — Posted on 2023-09-03
4475 Short-term consumption of ultra-processed semi-synthetic diets impairs the sense of smell and brain metabolism in mice
Makhlouf, M.; Souza, D.; Kurian, S.; Bellaver, B.; Ellis, H.; Kuboki, A.; Al-Naama, A.; Hasnah, R.; Venturin, G.; Costa, J.; Venugopal, N.; Manoel, D.; Reisert, J.; Tordoff, M. G.; Zimmer, E. R.; Saraiva, L. R.
10.1101/2023.08.31.555480 — neuroscience — Posted on 2023-09-03
4476 Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner
Maddhesiya, P.; Lepko, T.; Steiner-Mezzardi, A.; Schwarz, V.; Merl-Pham, J.; Berger, F.; Hauck, S. M.; Ronfani, L.; Bianchi, M.; Masserdotti, G.; Goetz, M.; Ninkovic, J.
10.1101/2023.08.31.555708 — neuroscience — Posted on 2023-09-03
4477 Modelling cognitive outcomes in the UK Biobank: education, noradrenaline and frontoparietal networks
Bravo-Merodio, L.; Williams, J. A.; Russ, D. R.; Gkoutos, G.; Bellgrove, M. A.; Chechlacz, M.
10.1101/2023.08.31.555645 — neuroscience — Posted on 2023-09-03
4478 Multi-omic dataset of patient-derived tumor organoids of neuroendocrine neoplasms
Alcala, N.; Voegele, C.; Mangiante, L.; Sexton-Oates, A.; Clevers, H.; Fernandez-Cuesta, L.; Dayton, T. L.; Foll, M.
10.1101/2023.08.31.555732 — cancer biology — Posted on 2023-09-03
4483 Promoting intestinal healing by exclusive enteral nutrition with TGF-beta in a mouse model of colitis.
Boumessid, K.; Lacroix, V.; Ovtchinnikova, E.; Quaranta-Nicaise, M.; Roy, M.; Dumay, A.; Thenet, S.; Carriere, M.; Mas, E.; Barreau, F.
10.1101/2023.08.31.555691 — physiology — Posted on 2023-09-03
4484 HCN channels sense temperature and determine heart rate responses to heat
Wu, Y.; Wang, Q.; Granger, J.; Reyes Gaido, O. E.; Aguilar, E. N.; Ludwig, A.; Moroni, A.; Bianchet, M. A.; Anderson, M. E.
10.1101/2023.09.02.556046 — physiology — Posted on 2023-09-03
4487 Open Access Repository-Scale Propagated Nearest Neighbor Suspect Spectral Library for Untargeted Metabolomics
Bittremieux, W.; Avalon, N. E.; Thomas, S. P.; Kakhkhorov, S. A.; Aksenov, A. A.; Portal Gomes, P. W.; Aceves, C. M.; Caraballo Rodriguez, A. M.; Gauglitz, J. M.; Huan, T.; Gerwick, W. H.; Jarmusch, A. K.; Kaddurah-Daouk, R. F.; Kang, K. B.; Kim, H. W.; Kondic, T.; Mannochio-Russo, H.; Meehan, M. J.; Melnik, A.; Nothias, L.-F.; O'Donovan, C.; Panitchpakdi, M.; Petras, D.; Schmid, R.; Schymanski, E. L.; van der Hooft, J. J. J.; Weldon, K. C.; Xing, S.; Yang, H.; Zemlin, J.; Wang, M.; Dorrestein, P. C.
10.1101/2022.05.15.490691 — bioinformatics — Posted on 2023-09-03
4489 Comparison of dental topography of marmosets and tamarins (Callitrichidae) to other platyrrhine primates using a novel freeware pipeline
de Vries, D.; Janiak, M. C.; Batista, R.; Boubli, J. P.; Goodhead, I. B.; Ridgway, E.; Boyer, D. M.; St. Clair, E.; Beck, R. M. D.
10.1101/2023.08.31.555703 — evolutionary biology — Posted on 2023-09-03
4492 Dysregulation of γδ intraepithelial lymphocytes precedes Crohn's disease-like ileitis
Xu, W.; Golovchenko, N. B.; Fong, A.; Achi, S.; Bucar, E. B.; Vidmar, K. J.; Zhang, L.; Frey, M. R.; Prinz, I.; Pizarro, T. T.; Kollias, G.; Edelblum, K. L.
10.1101/2023.08.31.555710 — immunology — Posted on 2023-09-03
4493 Motor neuron activity induces proteomic stress in the target muscle
Srivastav, S.; van der Graaf, K.; Jonnalagadda, P. C.; Thawani, M.; McNew, J. A.; Stern, M.
10.1101/2023.08.31.555699 — neuroscience — Posted on 2023-09-03
4494 Characterizing human postprandial metabolic response using multiway data analysis
Yan, S.; Li, L.; Horner, D.; Ebrahimi, P.; Chawes, B.; Dragsted, L. O.; Rasmussen, M. A.; Smilde, A. K.; Acar, E.
10.1101/2023.08.31.555521 — systems biology — Posted on 2023-09-03
4495 Losartan rewires ovarian cancer tumor-immune microenvironment and suppresses IGF-1 to amplify chemo-immunotherapy sensitivity
Sun, Y.; Yin, Z.; Wu, L.; Yue, C.; Zhang, Y.; Subudhi, S.; Lei, P.; Muzikansky, A.; Zhang, L.; Rueda, B. R.; Jain, R. K.; Xu, L.
10.1101/2023.08.31.555783 — cancer biology — Posted on 2023-09-03
4496 Cytoskeletal activation of NHE1 regulates cell volume and DNA methylation
Ni, Q.; Ge, Z.; Li, Y.; Shatkin, G.; Fu, J.; Bera, K.; Yang, Y.; Wang, Y.; Sen, A.; Wu, Y.; Vasconcelosi, A. C. N.; Feinberg, A. P.; Konstantopoulos, K.; Sun, S. X.
10.1101/2023.08.31.555808 — biophysics — Posted on 2023-09-03
4498 Human gut metagenomic mining reveals an untapped source of peptide antibiotics
Torres, M. D. T.; Brooks, E. F.; Cesaro, A.; Sberro, H.; Nicolaou, C.; Bhatt, A. S.; de la Fuente, C.
10.1101/2023.08.31.555711 — bioengineering — Posted on 2023-09-03
4500 In vivo perturb-seq of cancer and immune cells dissects oncologic drivers and therapy response
Liu, S. J.; Pak, J.; Zou, C.; Casey-Clyde, T.; Borah, A.; Wu, D.; Seo, K.; O'Loughlin, T.; Lim, D.; Ozawa, T.; Berger, M.; Weiss, W.; Raleigh, D. R.; Gilbert, L. A.
10.1101/2023.09.01.555831 — genomics — Posted on 2023-09-03
4505 PlasmidEC and gplas2: An optimised short-read approach to predict and reconstruct antibiotic resistance plasmids in Escherichia coli
Paganini, J. A.; Kerkvliet, J. J.; Vader, L.; Plantinga, N. L.; Meneses, R.; Corander, J.; Willems, R. J. L.; Arredondo-Alonso, S.; Schurch, A. C.
10.1101/2023.08.31.555679 — bioinformatics — Posted on 2023-09-03
4506 SpatialDDLS: An R package to deconvolute spatial transcriptomics data using neural networks
Mananes, D.; Rivero-Garcia, I.; Jimenez-Carretero, D.; Torres, M.; Sancho, D.; Torroja, C.; Sanchez-Cabo, F.
10.1101/2023.08.31.555677 — bioinformatics — Posted on 2023-09-03
4507 The type of DNA damage response after Decitabine treatment depends on the level of DNMT activity
Aumer, T.; Bergmayr, L.; Kartika, S.; Zeng, T.; Ge, Q.; Giorgio, G.; Daether, M.; Hess, A. J.; Michalakis, S.; Traube, F. R.
10.1101/2023.09.02.556017 — biochemistry — Posted on 2023-09-03
4509 Comparing peptide identifications by FAIMS versus quadrupole gas-phase fractionation
Faivre, D. A.; McGann, C. D.; Merrihew, G. E.; Schweppe, D. K.; MacCoss, M. J.
10.1101/2023.09.01.552989 — biochemistry — Posted on 2023-09-03
4510 Novel substrate prediction for the TAM family of RTKs using phosphoproteomics and structure-based modeling
Widstrom, N.; Andrianov, G.; Heier, J. L.; Heier, C. J.; Karanicolas, J. L.; Parker, L. L.
10.1101/2023.09.01.555943 — biochemistry — Posted on 2023-09-03
4516 Comprehensive analysis of A-type lamin tail region for repairing the nuclear lamina
Kono, Y.; Pack, C.-G.; Ichikawa, T.; Komatsubara, A.; Adam, S. A.; Rolas, L.; Nourshargh, S.; Medalia, O.; Goldman, R. D.; Fukuma, T.; Kimura, H.; Shimi, T.
10.1101/2023.09.02.555826 — cell biology — Posted on 2023-09-02
4517 Parkin is not required to sustain OXPHOS function in adult mammalian tissues
Filograna, R.; Gerlach, J.; Choi, H.-N.; Rigoni, G.; Barbaro, M.; Oscarson, M.; Lee, S.; Tiklova, K.; Ringner, M.; Koolmeister, C.; Wibom, R.; Riggare, S.; Nennesmo, I.; Perlmann, T.; Wredenberg, A.; Wedell, A.; Motori, E.; Svenningsson, P.; Larsson, N.-G.
10.1101/2023.09.02.556020 — cell biology — Posted on 2023-09-02
4519 Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome
Venkatraman, K.; Lee, C. T.; Garcia, G. C.; Mahapatra, A.; Milshteyn, D.; Perkins, G.; Kim, K.-Y.; Pasolli, H. A.; Phan, S.; Lippincott-Schwartz, J.; Ellisman, M.; Rangamani, P.; Budin, I.
10.1101/2023.03.13.532310 — biophysics — Posted on 2023-09-02
4521 Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis
Wilken, M.; Fonar, G.; Nations, C.; Pavani, G.; Gariffalou, J.; Tober, J.; Bennett, L. F.; Maguire, J. A.; Gagne, A.; Okoli, N.; Gadue, P.; Chou, S.; Speck, N. A.; French, D.; Thom, C. S.
10.1101/2023.09.01.555861 — cell biology — Posted on 2023-09-02
4522 Lipid levels correlate with neuronal and dopaminergic markers during the differentiation of SH-SY5Y cells
Marlet, F. R.; Munoz, S. S.; Sotiraki, N.; Eliasen, J. N.; Woessmann, J. P.; Dreier, J. E.; Schoof, E. M.; Kohlmeier, K. A.; Maeda, K.; Galvagnion, C.
10.1101/2023.09.01.555964 — cell biology — Posted on 2023-09-02
4525 Dual α-globin and truncated erythropoietin receptor knock-in restores hemoglobin production in α-thalassemia major-derived hematopoietic stem and progenitor cells
Chu, S. N.; Soupene, E.; Wienert, B.; Yin, H.; Sharma, D.; Jia, K.; Homma, S.; Hampton, J. P.; Gardner, J. M.; Conklin, B. R.; MacKenzie, T. C.; Porteus, M. H.; Cromer, M. K.
10.1101/2023.09.01.555926 — molecular biology — Posted on 2023-09-02
4528 Assessing the performance of protein regression models
Michael, R.; Kaestel-Hansen, J.; Groth, P. M.; Bartels, S.; Salomon, J.; Tian, P.; Hatzakis, N. S.; Boomsma, W.
10.1101/2023.06.18.545472 — bioinformatics — Posted on 2023-09-02
4529 Genetic and neural bases of the neuroticism general factor
Lee, J. J.; Kim, Y.; Giannelis, A.; Willoughby, E. A.; DeYoung, C. G.; Saunders, G. R. B.
10.1101/2023.03.08.531776 — genetics — Posted on 2023-09-02
4531 Single Cell Multi-Omics of an iPSC Model of Human Sinoatrial Node Development Reveals Genetic Determinants of Heart Rate and Arrhythmia Susceptibility
Engel, J. L.; Zhang, X.; Lu, D. R.; Vila, O. F.; Arias, V.; Lee, J.; Hale, C.; Hsu, Y.-H.; Li, C.-M. K.; Wu, R. S.; Vedantham, V.; Ang, Y.-S.
10.1101/2023.07.01.547335 — developmental biology — Posted on 2023-09-02
4535 Phage libraries screening on P53: yield improvement by zinc and a new parasites integrating analysis and rationale
Ben Abid, S.; Ketata, E.; Yacoubi-Hadj Amor, I.; Abdelmoula-Souissi, S.; Djemal, L.; Koubaa, A.; Mokdad-Gargouri, R.; Gargouri, A.
10.1101/2023.09.01.555989 — molecular biology — Posted on 2023-09-02
4539 Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti.
McNamara, C. J.; Ant, T. H.; Harvey-Samuel, T.; White-Cooper, H.; Martinez, J.; Alphey, L.; Sinkins, S. P.
10.1101/2023.09.01.555917 — microbiology — Posted on 2023-09-02
4540 Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin-antitoxin system
Baerentsen, R. L.; Nielsen, S. V.; Skjerning, R. B.; Lyngso, J.; Bisiak, F.; Pedersen, J. S.; Gerdes, K.; Sorensen, M. A.; Brodersen, D. E.
10.1101/2022.01.28.478185 — microbiology — Posted on 2023-09-02
4541 Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets
Plemper, R. K.; Cox, R.; Wolf, J. D.; Lieberman, N. A. P.; Lieber, C. M.; Kang, H.-J.; Sticher, Z. M.; Yoon, J.-J.; Andrews, M. K.; Govindarajan, M.; Krueger, R. E.; Sobolik, E. B.; Natchus, M. G.; Gewirtz, A.; deSwart, R.; Kolykhalov, A.; Hekmatyar, K.; Sakamoto, K.; Greninger, A. L.
10.1101/2023.09.01.555992 — microbiology — Posted on 2023-09-02
4542 Non-invasive Analysis of Peptidoglycan from Living Animals
Ocius, K. L.; Kolli, S. H.; Ahmad, S. S.; Dressler, J. M.; Jutras, B. L.; Chorida, M. D.; Rutkowski, M. R.; Pires, M.
10.1101/2023.07.21.549941 — microbiology — Posted on 2023-09-02
4546 Natural genetic variation quantitatively regulates heart-rate and -dimension
Gierten, J.; Welz, B.; Fitzgerald, T. W.; Thumberger, T.; Hummel, O.; Leger, A.; Weber, P.; Hassel, D.; Hubner, N.; Birney, E.; Wittbrodt, J.
10.1101/2023.09.01.555906 — genetics — Posted on 2023-09-02
4549 Automatic Ploidy Prediction and Quality Assessment of Human Blastocyst Using Time-Lapse Imaging
Rajendran, S.; Brendel, M.; Barnes, J.; Zhan, Q.; Malmsten, J. E.; Zisimopoulos, P.; Sigaras, A.; Ofori-Atta, K.; Meseguer Escriva, M.; Miller, K.; Hoffman, D.; Rosenwaks, Z.; Elemento, O.; Zaninovic, N.; Hajirasouliha, I.
10.1101/2023.08.31.555741 — developmental biology — Posted on 2023-09-02
4550 Na+/K+ATPase - Cav1.2 nanodomain differentially regulates intracellular and local adrenergic signaling in cardiac myocytes
Karbowski, M.; Boyman, L.; Garber, L.; Joca, H.; Verhoeven, N.; Coleman, A. K.; Ward, C.; Lederer, W. J.; Greiser, M.
10.1101/2023.08.31.553598 — physiology — Posted on 2023-09-02
4554 Conditional deletion of Ccl2 in smooth muscle cells does not reduce early atherosclerosis in mice
Gunnersen, S.; Shim, J. T.; Liu, F.; Tietge, U. J. F.; Sorensen, C. B.; Bentzon, J. F.
10.1101/2023.08.06.552177 — pathology — Posted on 2023-09-02
4555 A single-cell atlas of pig gastrulation as a resource for comparative embryology
Simpson, L.; Strange, A.; Klisch, D.; Kraunsoe, S.; Azami, T.; Goszczynski, D.; Le, T.; Planells, B.; Holmes, N.; Sang, F.; Henson, S.; Loose, M. W.; Nichols, J.; Alberio, R.
10.1101/2023.08.31.555712 — developmental biology — Posted on 2023-09-02
4560 A Single-Nucleus Atlas of Seed-to-Seed Development in Arabidopsis
Lee, T. A.; Nobori, T.; Illouz-Eliaz, N.; Xu, J.; Jow, B.; Nery, J. R.; Ecker, J. R.
10.1101/2023.03.23.533992 — plant biology — Posted on 2023-09-02
4561 Septin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function.
De Gasperi, R.; Csernoch, L.; Dienes, B.; Gonczi, M.; Chakrabarty, J. K.; Goeta, S.; Aslan, A.; Toro, C. A.; Karasik, D.; Brown, L. M.; Brotto, M.; Cardozo, C. P.
10.1101/2023.05.11.540467 — physiology — Posted on 2023-09-02
4565 Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring
Kuzmin, E.; Baker, T. M.; Lesluyes, T.; Monlong, J.; Abe, K. T.; Coelho, P. P.; Schwartz, M.; Zou, D.; Morin, G.; Pacis, A.; Yang, Y.; Martinez, C.; Barber, J.; Kuasne, H.; Li, R.; Bourgey, M.; Fortier, A.-M.; Davison, P. G.; Omeroglu, A.; Guiot, M. C.; Morris, Q.; Kleinman, C. L.; Huang, S.; Gingras, A.-C.; Ragoussis, I.; Bourque, G.; Van Loo, P.; Park, M.
10.1101/2023.06.10.544434 — genomics — Posted on 2023-09-02
4566 Single molecule long-read real-time amplicon-based sequencing of CYP2D6: a proof-of-concept with hybrid haplotypes
Dong, R.; Thamilselvan, M.; Foo, J. C.; DeJarnette, J.; Hu, X.; Carvalho Henriques, B.; Wang, Y.; Wallace, K.; Sivapalan, S.; Buchner, A.; Yavorskyy, V.; Martens, K.; Maier, W.; Henigsberg, N.; Hauser, J.; Cattaneo, A.; Mors, O.; Rietschel, M.; Pfeffer, G.; Aitchison, K. J.
10.1101/2022.08.17.503990 — genomics — Posted on 2023-09-02
4568 The evolutionary history of the common bean (Phaseolus vulgaris) revealed by chloroplast and nuclear genomes.
Frascarelli, G.; Galise, T. R.; D'Agostino, N.; Cafasso, D.; Cozzolino, S.; Cortinovis, G.; Sparvoli, F.; Bellucci, E.; Di Vittori, V.; Nanni, L.; Pieri, A.; Rossato, M.; Vincenzi, L.; Benazzo, A.; Delledonne, M.; Bitocchi, E.; Papa, R.
10.1101/2023.06.09.544374 — genetics — Posted on 2023-09-02
4570 Molecular evolution of male reproduction across species with highly divergent sperm morphology in diverse murine rodents
Kopania, E. E. K.; Thomas, G. W. C.; Hutter, C. R.; Mortimer, S. M. E.; Callahan, C. M.; Roycroft, E.; Achmadi, A. S.; Breed, W. G.; Clark, N. L.; Esselstyn, J. A.; Rowe, K. C.; Good, J. M.
10.1101/2023.08.30.555585 — evolutionary biology — Posted on 2023-09-02
4572 Inter-regional delays fluctuate in the human cerebral cortex
Moon, J.-Y.; Muesch, K.; Schroeder, C.; Valiante, T.; Honey, C.
10.1101/2022.06.01.494224 — neuroscience — Posted on 2023-09-02
4575 Effect of insulin insufficiency on ultrastructure and function in skeletal muscle
Kopecky, C.; Haug, M.; Reischl, B.; Deshpande, N.; Manandhar, B.; King, T.; Lee, V.; Wilkins, M.; Morris, M. J.; Polly, P.; Friedrich, O.; Rye, K.-A.; Cochran, B. J.
10.1101/2022.12.18.520900 — physiology — Posted on 2023-09-02
4576 The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous proteasome inhibitor resistant disease
Bishop, R. T.; Miller, A. K.; Froid, M.; Nerlakanti, N.; Li, T.; Frieling, J.; Nasr, M.; Nyman, K.; Sudalagunta, P.; Canevarolo, R.; Silva, A. S.; Shain, K. T.; Lynch, C.; Basanta, D.
10.1101/2022.11.13.516335 — cancer biology — Posted on 2023-09-02
4577 A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron binding protein FutA from Prochlorococcus
Bolton, R.; Machelett, M. M.; Stubbs, J.; Axford, D.; Caramello, N.; Catapano, L.; Maly, M.; Rodrigues, M. J.; Cordery, C.; Tizzard, G. J.; MacMillan, F.; Engilberge, S.; von Stetten, D.; Tosha, T.; Sugimoto, H.; Worrall, J. A.; Webb, J. S.; Zubkov, M.; Coles, S.; Mathieu, E.; Steiner, R. A.; Murshudov, G. N.; Schrader, T. E.; Orville, A. M.; Royant, A.; Evans, G.; Hough, M. A.; Owen, R.; Tews, I.
10.1101/2023.05.23.541926 — biophysics — Posted on 2023-09-02
4582 Demographically explicit scans for barriers to gene flow using gIMble
Laetsch, D. R.; Bisschop, G.; Martin, S. H.; Aeschbacher, S.; Setter, D.; Lohse, K.
10.1101/2022.10.27.514110 — evolutionary biology — Posted on 2023-09-02
4585 Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons
Bell, A. M.; Utting, C.; Hachisuka, J.; Dickie, A. C.; Kucharczyk, M. W.; Quillet, R.; Gutierrez-Mecinas, M.; Razlan, A. N. B.; Cooper, A. H.; Lan, Y.; Weir, G. A.; Bannister, K.; Watanabe, M.; Kania, A.; Hoon, M. A.; Macaulay, I. C.; Denk, F.; Todd, A.
10.1101/2023.08.20.553715 — neuroscience — Posted on 2023-09-02
4590 Versatile Tissue-Injectable Hydrogels with Extended Hydrolytic Release of Bioactive Protein Therapeutics
Nealy, E. S.; Reed, S. J.; Badeau, B. A.; Adelmund, S. M.; Shadish, J. A.; Pakiam, F. J.; Girard, E. J.; Price, J. P.; Mhyre, A. J.; Kalia, V.; Sarkar, S.; DeForest, C. A.; Olson, J. M.
10.1101/2023.09.01.554391 — bioengineering — Posted on 2023-09-02
4591 AIRR-C Human IG Reference Sets: curated sets of immunoglobulin heavy and light chain germline genes
Collins, A. M.; Ohlin, M.; Corcoran, M.; Heather, J. M.; Ralph, D.; Law, M.; Martinez-Barnetche, J.; Ye, J.; Richardson, E.; Gibson, W. S.; Rodriguez, O. L.; Peres, A.; Yaari, G.; Watson, C. T.; Lees, W. D.
10.1101/2023.09.01.555348 — genomics — Posted on 2023-09-01
4592 Sirenian genomes illuminate the evolution of fully aquatic species within the mammalian superorder Afrotheria
Tian, R.; Zhang, Y.; Kang, H.; Zhang, F.; Jin, Z.; Wang, J.; Zhang, P.; Zhou, X.; Lanyon, J.; Sneath, H.; Woolford, L.; Fan, G.; Li, S.; Seim, I.
10.1101/2023.09.01.555811 — evolutionary biology — Posted on 2023-09-01
4594 Lipid scrambling is a general feature of protein insertases
Li, D.; Rocha Roa, C.; Schilling, M. A.; Reinisch, K.; Vanni, S.
10.1101/2023.09.01.555937 — cell biology — Posted on 2023-09-01
4596 Space wandering in the rodent default mode network
Nghiem, T.-A. E.; Lee, B.; Chao, T.-H. H.; Branigan, N. K.; Mistry, P. K.; Shih, Y.-Y. I.; Menon, V.
10.1101/2023.08.31.555793 — neuroscience — Posted on 2023-09-02
4600 Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop
Wu, J.; Jonniya, N. A.; Hirakis, S. P.; Olivieri, C.; Veglia, G.; Kornev, A. P.; Taylor, S. S.
10.1101/2023.08.31.555822 — molecular biology — Posted on 2023-09-01
4601 S100A1's single cysteine is an indispensable redox-switch for the protection against diastolic calcium leakage in cardiomyocytes
Seitz, A.; Busch, M.; Kroemer, J.; Schneider, A.; Simon, S.; Jungmann, A.; Katus, H. A.; Most, P.; Ritterhoff, J.
10.1101/2023.09.01.555853 — molecular biology — Posted on 2023-09-01
4604 Dog Ecology and Rabies Knowledge, Attitude and Practice (KAP) in the Northern Communal Areas of Namibia
Tenzin, T.; Hikufe, E.; Hedimbi, N.; Athingo, R.; Shikongo, B.; Shuro, T.; Iipinge, J.; Herman, N.; Naunyango, M.; Haufiku, F.; Peter, J.; Hango, L.; Gottlieb, S.; Shoombe, K.; Denzin, N.; Busch, F.; Lohr, F.; Letshwenyo, M.; Torres, G.; Freuling, C. M.; Müller, T.; Shilongo, A.
10.1101/2023.09.01.555849 — microbiology — Posted on 2023-09-01
4605 Loss of RND3/RHOE controls entosis through LAMP1 expression in hepatocellular carcinoma
Basbous, S.; Dif, L.; Dantzer, C.; Di Tommaso, S.; Dupuy, J.-W.; Bioulac-Sage, P.; Raymond, A.-A.; Desdouets, C.; Saltel, F.; Moreau, V.
10.1101/2023.09.01.555890 — cancer biology — Posted on 2023-09-01
4611 Sequential early-life viral infections modulate the microbiota and adaptive immune responses to systemic and mucosal vaccination
Li, Y.; Molleston, J. M.; Kim, A. H.; Ingle, H.; Aggarwal, S.; Nolan, L.; Hassan, A.; Foster, L.; Diamond, M.; Baldridge, M. T.
10.1101/2023.08.31.555772 — microbiology — Posted on 2023-09-01
4613 Characterization of an EG.5.1 clinical isolate in vitro and in vivo
Uraki, R.; Kiso, M.; Iwatsuki-Horimoto, K.; Yamayoshi, S.; Ito, M.; Chiba, S.; Sakai-Tagawa, Y.; Imai, M.; Kashima, Y.; Koga, M.; Fuwa, N.; Okumura, N.; Hojo, M.; Iwamoto, N.; Kato, H.; Nakajima, H.; Ohmagari, N.; Yotsuyanagi, H.; Suzuki, Y.; Kawaoka, Y.
10.1101/2023.08.31.555819 — microbiology — Posted on 2023-09-01
4614 Equine dermatitis outbreak associated with parapoxvirus
Virtanen, J.; Hautala, K.; Utriainen, M.; Dutra, L.; Eskola, K.; Airas, N.; Uusitalo, R.; Ahvenainen, E.; Smura, T.; Sironen, T.; Vapalahti, O.; Kant, R.; Virtala, A.-M.; Kinnunen, P. M.
10.1101/2023.09.01.555671 — microbiology — Posted on 2023-09-01
4618 Multifaceted proteome analysis at solubility, redox, and expression dimensions for target identification
Saei, A. A.; Lundin, A.; Lyu, H.; Gharibi, H.; Luo, H.; Teppo, J.; Zhang, X.; Gaetani, M.; Vegvari, A.; Holmdahl, R.; Gygi, S. P.; Zubarev, R. A.
10.1101/2023.08.31.555796 — biochemistry — Posted on 2023-09-01
4619 SIDERITE: Unveiling Hidden Siderophore Diversity in the Chemical Space Through Digital Exploration
He, R.; Gu, S.; Xu, J.; Li, X.; Chen, H.; Shao, Z.; Wang, H.; Shao, J.; Yin, W.-B.; Qian, L.; Wei, Z.; Li, Z.
10.1101/2023.08.31.555687 — biochemistry — Posted on 2023-09-01
4620 Chemoproteomic profiling of 8-oxoguanosine-sensitive RNA-protein interactions
Villers, J.; McCann Smith, E.; DeLiberto, A. N.; Arguello, A. E.; Nyaanga, J.; Kleiner, R. E.
10.1101/2023.09.01.555928 — biochemistry — Posted on 2023-09-01
4621 Profiling plasma extracellular vesicle-derived microRNAs for noninvasive diagnosis of alpha-1 antitrypsin deficiency associated liver disease
Oshins, R.; Huo, Z.; Poole, B.; Clark, V.; Zhou, H.; West, J.; Wheeler, M.; Aghaee, M.; He, M.; Brantly, M.; Khodayari, N.
10.1101/2023.08.31.555751 — molecular biology — Posted on 2023-09-01
4623 Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
Lee, J. D.; Menasche, B. L.; Mavrikaki, M.; Uyemura, M. M.; Hong, S. M.; Kozlova, N.; Wei, J.; Alfajaro, M. M.; Filler, R.; Muller, A.; Saxena, T.; Posey, R. R.; Cheung, P.; Muranen, T.; Heng, J.; Paulo, J. A.; Wilen, C. B.; Slack, F. J.
10.1101/2023.08.31.555625 — microbiology — Posted on 2023-09-01
4624 Consideration of a liquid mutation accumulation experiment to measure mutation rates by successive serial dilution.
Baehr, S.; Ho, W.-C.; Perez, S.; Cenzano, A.; Hancock, K.; Patrick, L.; Brown, A.; MIller, S.; Lynch, M.
10.1101/2023.08.31.555790 — microbiology — Posted on 2023-09-01
4626 Cell wall fluidization by mechano-endopeptidases sets up a turgor-mediated volumetric pacemaker
Mukherjee, A.; Huang, Y.; Oh, S.; Sanchez, C.; Chang, Y.-F.; Liu, X.; Bradshaw, G. A.; Benites, N. C.; Paulsson, J.; Kirschner, M. W.; Sung, Y.; Elgeti, J.; Basan, M.
10.1101/2023.08.31.555748 — microbiology — Posted on 2023-09-01
4628 SARS-CoV-2 hijacks fragile X mental retardation proteins for efficient infection
Garvanska, D.; Alvarado, R. E.; Mundt, F.; Nilsson, E.; Duel, J.; Coscia, F.; Lindqvist, R.; Lokugamage, K.; Johnson, B.; Plante, J. A.; Morris, D. R.; Vu, M. N.; Estes, L.; McLeland, A.; Walker, J.; Crocquet-Valdes, P.; Lopez-Mendez, B.; Plante, K.; Walker, D. H.; Weisser, M. B.; Overby, A. K.; Mann, M.; Menachery, V. D.; Nilsson, J.
10.1101/2023.09.01.555899 — microbiology — Posted on 2023-09-01
4629 Community ecology of phages on a clonal bacterial host
Pyenson, N. C.; Leeks, A.; Nweke, O.; Goldford, J.; Turner, P.; Foster, K. R.; Sanchez, A.
10.1101/2023.09.01.555216 — microbiology — Posted on 2023-09-01
4630 Rof is a key regulator of Rho and transcription termination in bacteria
Zhang, J.; Zhang, S.; Zhou, W.; Zhang, X.; Li, G.; Li, L.; Lin, X.; Liu, F.; Gao, Y.; Chen, Z.; Chao, Y.; Wang, C.
10.1101/2023.09.01.555900 — microbiology — Posted on 2023-09-01
4631 Characterization of low copy number human angiotensin-convertase 2 (hACE2)-transgenic mice as an improved model of SARS-CoV-2 infection
Bradshaw, C. M.; Georgieva, T.; Tankersley, T. N.; Taylor-Doyle, T.; Johnson, L.; Uhrlaub, J. L.; Besselsen, D.; Nikolich, J. Z.
10.1101/2023.08.31.555800 — immunology — Posted on 2023-09-01
4633 Nitrogen availability during domestication shaped the divergence of tetraploid wheat
Pieri, A.; Beleggia, R.; Gioia, T.; Tong, H.; Di Vittori, V.; Frascarelli, G.; Bitocchi, E.; Nanni, L.; Bellucci, E.; Fiorani, F.; Pecchioni, N.; Marzario, S.; De Quattro, C.; Limongi, A. R.; De Vita, P.; Rossato, M.; Schurr, U.; David, J.; Nikoloski, Z.; Papa, R.
10.1101/2023.08.31.555682 — genetics — Posted on 2023-09-01
4635 Repeat turnover meets stable chromosomes: repetitive DNA sequences mark speciation and gene pool boundaries in sugar beet and wild beets
Schmidt, N.; Sielemann, K.; Breitenbach, S.; Fuchs, J.; Pucker, B.; Weisshaar, B.; Holtgräwe, D.; Heitkam, T.
10.1101/2023.09.01.555723 — genomics — Posted on 2023-09-01
4636 Belt and braces: two escape ways to maintain the cassette reservoir of large chromosomal integrons
Richard, E.; Darracq, B.; Littner, E.; Millot, G.; Conte, V.; Cokelaer, T.; Engelstaedter, J.; Rocha, E.; Mazel, D.; Loot, C.
10.1101/2023.08.31.555669 — genetics — Posted on 2023-09-01
4638 The Dynamics of the Female Microbiome: Unveiling Abrupt Changes of Microbial Domains across Body Sites from Preconception to Perinatal Phase
Neumann, C. J.; Pausan, M.-R.; Haid, V.; Weiss, E.-C.; Kolovetsiou-Kreiner, V.; Amtmann, B.; Winkler, P.; Mahnert, A.; Jantscher-Krenn, E.; Moissl-Eichinger, C.
10.1101/2023.08.31.555744 — microbiology — Posted on 2023-09-01
4639 Metabolic Dependency Shapes Bivalent Antiviral Response in Host Cells: The Role of Glutamine
Lebeau, G.; Paulo-Ramos, A.; Hoareau, M.; El Safadi, D.; Meilhac, O.; Krejbich-Trotot, P.; Roche, M.; Viranaicken, W.
10.1101/2023.08.31.555729 — immunology — Posted on 2023-09-01
4643 SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells
Zhang, L.; Hsu, J. I.; Braekeleer, E. D.; Chen, C.-w.; Patel, T. D.; Urya, H.; Guzman, A. G.; Martell, A. G.; Waldvogel, S. M.; Tovy, A.; Callen, E.; Murdaugh, R. L.; Richard, R. U.; Jansen, S.; Vissers, L.; de Vries, B. B.; Nussenzweig, A.; Huang, S.; Coarfa, C.; Anastas, J. N.; Takahashi, K.; Vassiliou, G. S.; Goodell, M. A.
10.1101/2023.08.31.555634 — cancer biology — Posted on 2023-09-01
4644 Gene expression analysis suggests immunosuppressive roles of endolysosomes in glioblastoma
Sun, M. A.; Yao, H.; Yang, Q.; Pirozzi, C. J.; Chandramohan, V.; Ashley, D. M.; He, Y.
10.1101/2023.08.31.555740 — cancer biology — Posted on 2023-09-01
4646 ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats
Grillo, G.; Boyarchuk, E.; Mihic, S.; Ivkovic, I.; Bertrand, M.; Jouneau, A.; Dahlet, T.; Dumas, M.; Weber, M.; Velasco, G.; Francastel, C.
10.1101/2023.08.31.555516 — genomics — Posted on 2023-09-01
4648 Identification and copy number variant analysis of enhancer regions of genes causing spinocerebellar ataxia
Ghorbani, F.; de Boer, E.; Fokkens, M. R.; de Boer-Bergsma, J.; Verschuuren-Bemelmans, C. C.; Wierenga, E.; Kasaei, H.; Noordermeer, D.; Verbeek, D. S.; Westers, H.; van Diemen, C. C.
10.1101/2023.08.31.555719 — genetics — Posted on 2023-09-01
4650 HIF-1α-mediated mitochondrial-glycolytic reprogramming controls the transition of precursor to terminally exhausted T cells
Wu, H.; Zhao, X.; Hochrein, S. M.; Eckstein, M.; Gubert, G. F.; Knoepper, K.; Mansilla, A. M.; Oener, A.; Doucet-Ladeveze, R.; Schmitz, W.; Ghesquiere, B.; Theurich, S.; Dudek, J.; Gasteiger, G.; Zernecke-Madsen, A.; Kobold, S.; Kastenmueller, W.; Vaeth, M.
10.1101/2023.08.31.555662 — immunology — Posted on 2023-09-01
4651 Single-cell immune multi-omics and repertoire analyses in pancreatic ductal adenocarcinoma reveal differential immunosuppressive mechanisms within different tumour microenvironments
Sivakumar, S.; Jainarayanan, A.; Arbe-Barnes, E.; Leathlobhair, M. N.; Sharma, P. K.; Amin, S.; Heij, L.; Hegde, S.; Magen, A.; Tucci, F.; Sun, B.; Wu, S.; Anand, N. M.; Slawinski, H.; Revale, S.; Nassiri, I.; Webber, J.; Frampton, A.; Wiltberger, G.; Neumann, U. P.; Charlton, P.; Spiers, L.; Elliott, T.; Sivakumar, P. V.; Ratushny, A. V.; Middleton, M.; Peppa, D.; Fairfax, B.; Merad, M.; Dustin, M. L.; Abu-Shah, E.; Bashford-Rogers, R. J. M.
10.1101/2023.08.31.555730 — immunology — Posted on 2023-09-01
4652 Cryo-EM structures of Tau filaments from the brains of mice transgenic for human mutant P301S Tau
Schweighauser, M.; Murzin, A. G.; McDonald, J.; Lavenir, I. L.; Crowther, R. A.; Scheres, S.; Goedert, M.
10.1101/2023.08.31.555656 — neuroscience — Posted on 2023-09-01
4653 Enhancement of Protein Stability by Quenching Millisecond Conformational Dynamics
Hou, X.-N.; Zhao, C.; Song, B.; Ruan, M.-X.; Dong, X.; Gong, Z.; Weng, X.-X.; Zheng, J.; Tang, C.
10.1101/2023.08.30.555640 — biophysics — Posted on 2023-09-01
4654 Human Ageing Genomic Resources: updates on key databases in ageing research
de Magalhaes, J. P.; Abidi, Z.; Arantes dos Santos, G.; Avelar, R. A.; Barardo, D.; Chatsirisupachai, K.; Clark, P.; de Souza, E.; Johnson, E. J.; Lopes, I.; Novoa, G.; Senez, L.; Talay, A.; Thornton, D.; To, P. K. P.
10.1101/2023.08.30.555622 — bioinformatics — Posted on 2023-09-01
4655 Early life adversity has sex-dependent effects on survival across the lifespan in rhesus macaques
Patterson, S. K.; Andonov, E.; Arre, A. M.; Martinez, M. I.; Negron-Del Valle, J. E.; Petersen, R. M.; Phillips, D.; Rahman, A.; Ruiz-Lambides, A.; Villanueva, I.; Lea, A. J.; Snyder-Mackler, N.; Brent, L. J. N.; Higham, J. P.
10.1101/2023.08.30.555589 — animal behavior and cognition — Posted on 2023-09-01
4657 Adrenergic and mesenchymal signatures are identifiable in cell-free DNA and correlate with metastatic disease burden in children with neuroblastoma
Vayani, O. R.; Kaufman, M. E.; Moore, K.; Chennakesavalu, M.; Terhaar, R.; Chaves, G.; Chlenski, A.; He, C.; Cohn, S. L.; Applebaum, M. A.
10.1101/2023.08.30.554943 — genomics — Posted on 2023-09-01
4659 Rapid measurement and statistical ranking of leaf drought tolerance capacity in cotton
Dong, X.; Mott, D. A.; Garg, J.; Zhou, Q.; Sunoj V. S., J.; McKnight, B. M.
10.1101/2023.08.30.555618 — ecology — Posted on 2023-09-01
4660 Foodscapes for Salmon and Other Mobile Consumers in River Networks
Rossi, G.; Bellmore, J. R.; Armstrong, J. B.; Jeffres, C.; Naman, S. M.; Carlson, S. M.; Grantham, T. E.; Kaylor, M. J.; White, S.; Katz, J.; Power, M. E.
10.1101/2023.08.30.555604 — ecology — Posted on 2023-09-01
4661 Dual role of Vascular Endothelial Growth Factor-C (VEGF-C) in post-stroke recovery
Choi, Y. H.; Hsu, M.; Laaker, C.; Herbath, M.; Yang, H.; Cismaru, P.; Johnson, A. M.; Spellman, B.; Wigand, K.; Sandor, M.; Fabry, Z.
10.1101/2023.08.30.555144 — immunology — Posted on 2023-09-01
4662 A Two-Step Activation Mechanism Enables Mast Cells to Differentiate their Response between Extracellular and Invasive Enterobacterial Infection
von Beek, C.; Fahlgren, A.; Geiser, P.; Di Martino, M. L.; Lindahl, O.; Prensa, G. I.; Mendez-Enriquez, E.; Eriksson, J.; Hallgren, J.; Fällman, M.; Pejler, G.; Sellin, M. E.
10.1101/2023.08.31.555657 — immunology — Posted on 2023-09-01
4663 Large-scale annotated dataset for cochlear hair cell detection and classification
Buswinka, C. J.; Rosenberg, D. B.; Simikyan, R. G.; Osgood, R. T.; Fernandez, K.; Nitta, H.; Hayashi, Y.; Liberman, L. W.; Nguyen, E.; Yildiz, E.; Kim, J.; Jarysta, A.; Renauld, J.; Wesson, E.; Thapa, P.; Bordiga, P.; McMurtry, N.; Llamas, J.; Kitcher, S. R.; Lopez-Porras, A. I.; Cui, R.; Behnammanesh, G.; Bird, J. E.; Ballesteros, A.; Velez-Ortega, A. C.; Edge, A. S.; Deans, M.; Gnedeva, K.; Shrestha, B. R.; Manor, U.; Zhao, B.; Ricci, A. J.; Tarchini, B.; Basch, M.; Stepanyan, R. S.; Landegger, L. D.; Rutherford, M.; Liberman, M. C.; Walters, B. J.; Kros, C.; Richardson, G. P.; Cunningham, L
10.1101/2023.08.30.553559 — neuroscience — Posted on 2023-09-01
4664 DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates neuroinflammation and amyloid-β deposition in Alzheimer's disease
Daily, K. P.; Badr, A.; Eltobgy, M.; Estfanous, S.; Whitham, O.; Tan, M.; Carafice, C.; Krause, K.; McNamara, A.; Hamilton, K.; Houle, S.; Gupta, S.; Gupta, G.; Madhu, S.; Fitzgerald, J.; Saadey, A.; Laster, B.; Yan, P.; Webb, A.; Zhang, X.; Pietrzak, M.; Kokiko-Cochran, O. N.; Ghoneim, H. E.; Amer, A. O.
10.1101/2023.08.30.555526 — neuroscience — Posted on 2023-09-01
4667 A unified open-source platform for multimodal neural recording and perturbation during naturalistic behavior
Newman, J. P.; Zhang, J.; Cuevas-Lopez, A.; Miller, N. J.; Honda, T.; van der Goes, M.-S. H.; Leighton, A. H.; Carvalho, F.; Lopes, G.; Lakunina, A.; Siegle, J. H.; Harnett, M. T.; Wilson, M. A.; Voigts, J.
10.1101/2023.08.30.554672 — neuroscience — Posted on 2023-09-01
4668 Pathological brain states in Alzheimer's disease
Adams, J. N.; Kark, S. M.; Chappel-Farley, M. G.; Escalante, Y.; Stith, L. A.; Rapp, P. E.; Yassa, M. A.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.08.30.555617 — neuroscience — Posted on 2023-09-01
4669 Hybrid Amyloid Quantum Dot Nanoassemblies to Probe Neuroinflammatory Damage
Chiang, W.; Urban, J. N.; Yanchik-Slade, F.; Stout, A.; Nilsson, B. L.; Gelbard, H. A.; Krauss, T. D.
10.1101/2023.08.30.555592 — neuroscience — Posted on 2023-09-01
4670 White spot syndrome virus endogenous viral elements (EVE) revealed by circular viral copy DNA (cvcDNA) in shrimp
Taengchaiyaphum, S.; Srisala, J.; Wongklaluang, P.; Sukthaworn, S.; Macias, J.; Udin, I. I.; Chokkara, M. B.; Athikkavil, M. M.; Sanz, V. A.; Flegel, T. W.; Sritunyalucksana, K.
10.1101/2023.08.30.554989 — zoology — Posted on 2023-09-01
4671 Chemical Tools for Profiling the Intracellular ADP-ribosylated Proteome
Draganov, S. D.; Gruet, M. J.; Conole, D.; Balcells, C.; Siskos, A. P.; Keun, H. C.; Haskard, D. O.; Tate, E. W.
10.1101/2023.08.30.555609 — systems biology — Posted on 2023-09-01
4672 Myostatin is a major endocrine driver of follicle-stimulating hormone synthesis
Ongaro, L.; Zhou, X.; Wang, Y.; Zhou, Z.; Schultz, H.; Buddle, E. R. S.; Brule, E.; Lin, Y.-F.; Schang, G.; Castonguay, R.; Liu, Y.; Su, G. H.; Seidah, N.; Ray, K. C.; Karp, S. J.; Boehm, U.; Lee, S.-J.; Bernard, D. J.
10.1101/2023.08.30.555595 — physiology — Posted on 2023-09-01
4673 Estrogen prevents age-dependent beige adipogenesis failure through NAMPT-controlled ER stress pathway
Park, J.; Hu, R.; Xiong, S.; Qian, Y.; El-Sabbagh, A. S.; Ibrahim, M.; Song, Q.; Yan, G.; Song, Z.; Mahmoud, A. M.; He, Y.; Layden, B. T.; Chen, J.; Ong, S.-G.; Xu, P. W.; Jiang, Y.
10.1101/2023.08.31.555821 — physiology — Posted on 2023-09-01
4676 Chromatin Profiling of CBFA2T3-GLIS2 AMLs Identifies Key Transcription Factor Dependencies and BRG1 Inhibition as a Novel Therapeutic Strategy
Kaonis, S.; Smith, J. L.; Katiyar, N.; Merrill, M.; Hylkema, T.; Namciu, S.; Le, Q.; Babaeva, E.; Ikeda, T.; Morris, S. M.; Girard, E.; Furuyama, S.; Ries, R.; Bernstein, I.; Meshinchi, S.; Henikoff, S.; Meers, M. P.; Hadland, B. K.; Sarthy, J. F.
10.1101/2023.08.30.555598 — cancer biology — Posted on 2023-09-01
4679 Exploring "dark matter" protein folds using deep learning
Harteveld, Z.; Van Hall-Beauvais, A.; Morozova, I.; Southern, J.; Goverde, C. A.; Georgeon, S.; Rosset, S.; Loukas, A.; Vandergheynst, P.; Bronstein, M.; Correia, B.
10.1101/2023.08.30.555621 — bioinformatics — Posted on 2023-09-01
4680 Finding Candida auris in public metagenomic repositories
Mario-Vasquez, J. E.; Bagal, U. R.; Lowe, E.; Morgulis, A.; Phan, J.; Sexton, D. J.; Shiryev, S.; Slatkevicius, R.; Welsh, R.; Litvintseva, A. P.; Blumberg, M.; Agarwala, R.; Chow, N. A.
10.1101/2023.08.30.555569 — bioinformatics — Posted on 2023-09-01
4686 Molecular evolution of male reproduction across species with highly divergent sperm morphology in diverse murine rodents
Kopania, E. E. K.; Thomas, G. W. C.; Hutter, C. R.; Mortimer, S. M. E.; Callahan, C. M.; Roycroft, E.; Achmadi, A. S.; Breed, W. G.; Clark, N. L.; Esselstyn, J. A.; Rowe, K. C.; Good, J. M.
10.1101/2023.08.30.555585 — evolutionary biology — Posted on 2023-09-01
4689 Natural gene variation in Cannabis sativa unveils a key region of cannabinoid synthase enzymes
Villard, C.; Bayer, C.; Medici, N. P.; van de Peppel, A. C.; Cankar, K.; Verstappen, F.; Kappers, I. F.; Schranz, M. E.; Daniel, B.; van Velzen, R.
10.1101/2023.08.30.555511 — molecular biology — Posted on 2023-09-01
4690 Development and validation of a respiratory syncytial virus multiplex immunoassay
Marsall, P.; Fandrich, M.; Griesbaum, J.; Harries, M.; Lange, B.; RESPINOW study consortium, ; Ascough, S.; Dayananda, P.; Chiu, C.; Remppis, J.; Ganzenmueller, T.; Renk, H.; Strengert, M.; Schneiderhan-Marra, N.; Dulovic, A.
10.1101/2023.08.30.555534 — immunology — Posted on 2023-09-01
4692 Vgamma9Vdelta2 T cells recognize butyrophilin 2A1 and 3A1 heteromers
Fulford, T. S.; Soliman, C.; Castle, R. G.; Rigau, M.; Ruan, Z.; Dolezal, O.; Seneviratna, R.; Brown, H. G.; Hanssen, E.; Hammet, A.; Li, S.; Redmond, S. J.; Chung, A.; Gorman, M. A.; Parker, M. W.; Patel, O.; Peat, T. S.; Newman, J.; Behren, A.; Gherardin, N. A.; Godfrey, D. I.; Uldrich, A. P.
10.1101/2023.08.30.555639 — immunology — Posted on 2023-09-01
4693 Navigating Pubertal Goldilocks: The Optimal Pace for Hierarchical Brain Organization
Szakacs, H. M.; Mutlu, M. C.; Balestrieri, G.; Gombos, F.; Braun, J.; Kringelbach, M. L.; Deco, G.; Kovacs, I.
10.1101/2023.08.30.555584 — neuroscience — Posted on 2023-09-01
4696 Translocation of gut commensal bacteria to the brain
Thapa, M.; Kumari, A.; Chin, C.-Y.; Choby, J.; Jin, F.; Bogati, B.; Chopyk, D.; Koduri, N.; Pahnke, A.; Elrod, E.; Burd, E. M.; Weiss, D. S.; Grakoui, A.
10.1101/2023.08.30.555630 — neuroscience — Posted on 2023-09-01
4697 Heterotypic stressors unmask behavioral influences of PMAT deficiency
Weber, B. L.; Nicodemus, M. M.; Hite, A. K.; Spalding, I. R.; Beaver, J. N.; Scrimshaw, L. R.; Kassis, S. K.; Reichert, J. M.; Ford, M. T.; Russell, C. N.; Hallal, E. M.; Gilman, T. L.
10.1101/2023.08.30.555632 — neuroscience — Posted on 2023-09-01
4702 NADPH oxidase 4-derived hydrogen peroxide counterbalances testosterone-induced endothelial dysfunction and migration
Alves, J. V.; Costa, R. M.; Awata, W. M.; Bruder-Nascimento, A.; Singh, S.; Tostes, R. C.; Bruder-Nascimento, T.
10.1101/2023.08.30.555550 — pharmacology and toxicology — Posted on 2023-09-01
4703 Hsa_circ_0005397 could promote hepatocellular carcinoma progression and metastasis through EIF4A3
Yuan, L.; Luo, M.; Liu, R.-Y.; Wang, H.-X.; Ju, L.-L.; Wang, F.; Cao, L.-Y.; Wang, Z.-C.; Chen, L.
10.1101/2023.08.30.555568 — cancer biology — Posted on 2023-09-01
4704 Logistic tumor-population growth and ghost-points symmetry
Pasetto, S.; Harshe, I.; Brady, R.; Gatenby, R.; Enderling, H.
10.1101/2023.08.30.555578 — cancer biology — Posted on 2023-09-01
4705 Vitamin D promotes DNase1L3 to degrade ecDNA and inhibit the malignant progression of hepatocellular carcinoma
Sun, T.; Zhang, H.; Qin, L.-n.; Li, Q.-q.; Wu, T.; Zhang, L.; Wang, K.-w.; Cheng, S.-b.; Shi, Y.; Feng, Y.-q.; Han, J.-x.; Li, Y.-n.; Li, Z.-y.; Liu, H.-j.
10.1101/2023.08.30.555532 — cancer biology — Posted on 2023-09-01
4709 Analysis and Modeling of Early Estradiol-induced GREB1 Single Allele Gene Transcription at the Population Level
Ghasemi, M. S.; Singh, P. K.; Johnson, H. L.; Koksoy, A.; Mancini, M.; Stossi, F.; Azencott, R.
10.1101/2023.08.30.555527 — bioinformatics — Posted on 2023-09-01
4711 Tunable biomimetic materials elaborated by ice templating and self-assembly of collagen for tubular tissue engineering
Martinier, I.; Fage, F.; Kakar, A.; Castagnino, A.; Saindoy, E.; Frederick, J.; Onorati, I.; Besnard, V.; Barakat, A.; Dard, N.; Martinod, E.; Planes, C.; Trichet, L.; Fernandes, F. M.
10.1101/2023.08.30.555553 — bioengineering — Posted on 2023-09-01
4712 Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis
Aygün, N.; Krupa, O.; Mory, J.; Le, B.; Valone, J.; Liang, D.; Love, M. I.; Stein, J. L.
10.1101/2023.08.30.555019 — genomics — Posted on 2023-09-01
4715 The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017
Catani, J. P.; Smet, A.; Ysenbaert, T.; Vuylsteke, M.; Bottu, G.; Mathys, J.; Botzki, A.; Cortes-Garcia, G.; Strudnell, T.; Gomila, R.; Hamberger, J.; Catalan, J.; Ustyugova, I.; Farrell, T.; Stegalkina, S.; Ray, S.; LaRue, L.; Saelens, X.; Vogel, T. U.
10.1101/2023.08.30.555500 — immunology — Posted on 2023-09-01
4716 Using neural biomarkers to personalize dosing of vagus nerve stimulation
Berthon, A.; Wernisch, L.; Stoukidi, M.; Thornton, M.; Tessier-Lariviere, O.; Fortier-Poisson, P.; Mamen, J.; Pinkney, M.; Lee, S.; Sarkans, E.; Annecchino, L.; Appleton, B.; Garsed, P.; Patterson, B.; Gonshaw, S.; Jakopec, M.; Shunmugam, S.; Edwards, T.; Tukiainen, A.; Jennings, J.; Lajoie, G.; Hewage, E.; Armitage, O.
10.1101/2023.08.30.555487 — neuroscience — Posted on 2023-09-01
4717 Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory
Voglewede, M. M.; Ozsen, E. N.; Ivak, N.; Bernabucci, M.; Sun, M.; Pang, Z. P.; Zhang, H.
10.1101/2023.08.30.555530 — neuroscience — Posted on 2023-09-01
4718 The Neural Basis of Drosophila Courtship Song
Lillvis, J. L.; Wang, K.; Shiozaki, H. M.; Xu, M.; Stern, D. L.; Dickson, B. J.
10.1101/2023.08.30.555537 — neuroscience — Posted on 2023-09-01
4720 The olfactory-based neurofeedback of the EEG alpha rhythm
Medvedeva, A.; Ninenko, I.; Kleeva, D. F.; Fedoseev, A.; Bazhenov, A.; Cabrera, M. A.; Tsetserukou, D.; Lebedev, M. A.
10.1101/2023.08.30.555545 — neuroscience — Posted on 2023-09-01
4722 Accurate Prediction of Antibody Function and Structure Using Bio-Inspired Antibody Language Model
Jing, H.; Gao, Z.; Xu, S.; Shen, T.; Peng, Z.; He, S.; You, T.; Ye, S.; Lin, W.; Sun, S.
10.1101/2023.08.30.555473 — bioinformatics — Posted on 2023-09-01
4723 Omix: A Multi-Omics Integration Pipeline
Schneegans, E.; Fancy, N.; Thomas, M.; Willumsen, N.; Matthews, P. M.; Jackson, J.
10.1101/2023.08.30.555486 — bioinformatics — Posted on 2023-09-01
4727 Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS
Mosegaard, S.; Twayana, K.; Denis, S.; Kroon, J.; Schomakers, B. V.; van Weeghel, M.; Houtkooper, R.; Olsen, R. K. J.; Holm, C. K.
10.1101/2023.08.30.555512 — immunology — Posted on 2023-09-01
4730 Sex classification from functional brain connectivity: Generalization to multiple datasets
Wiersch, L.; Friedrich, P.; Hamdan, S.; Komeyer, V.; Hoffstaedter, F.; Patil, K. R.; Eickhoff, S. B.; Weis, S.
10.1101/2023.08.30.555495 — neuroscience — Posted on 2023-09-01
4732 Online Bayesian Optimization of Nerve Stimulation
Wernisch, L.; Edwards, T.; Berthon, A.; Tessier-Lariviere, O.; Sarkans, E.; Stoukidi, M.; Fortier-Poisson, P.; Pinkney, M.; Thornton, M.; Hanley, C.; Lee, S.; Jennings, J.; Appleton, B.; Garsed, P.; Patterson, B.; Buttinger, W.; Gonshaw, S.; Jakopec, M.; Shunmugam, S.; Mamen, J.; Tukiainen, A.; Lajoie, G.; Armitage, O.; Hewage, E.
10.1101/2023.08.30.555315 — neuroscience — Posted on 2023-09-01
4737 Chromatin priming elements direct tissue-specific gene activity prior to hematopoietic specification
Maytum, A.; Edginton-White, B.; Keane, P.; Cockerill, P. N.; Cazier, J.-B.; Bonifer, C.
10.1101/2023.08.30.555485 — genomics — Posted on 2023-09-01
4738 Human hippocampal ripples tune cortical responses in uncertain visual contexts
Frank, D.; Moratti, S.; Sarnthein, J.; Li, N.; Horn, A.; Imbach, L.; Stieglitz, L.; Gil-Nagel, A.; Toledano, R.; Friston, K. J.; Strange, B. A.
10.1101/2023.08.30.555474 — neuroscience — Posted on 2023-09-01
4739 All-optical reporting of chloride ion driving force in the nervous system.
Selfe, J. S.; Steyn, T. J. S.; Shorer, E. F.; Burman, R. J.; Dusterwald, K. M.; Abdelfattah, A. S.; Schreiter, E. R.; Newey, S. E.; Akerman, C. J.; Raimondo, J. V.
10.1101/2023.08.30.555464 — neuroscience — Posted on 2023-09-01
4740 Skeletal Muscle Phenotype-Specific Effects of ACVR1B and TGFBR1 Receptor Signalling on Muscle Transcriptome, Force generation and Metabolism
Shi, A.; Hillege, M. M. G.; Noort, W.; Offringa, C.; Wu, G.; Forouzanfar, T.; Hoogaars, W. M. H.; Wust, R. C. I.; Jaspers, R. T.
10.1101/2023.08.30.555466 — physiology — Posted on 2023-09-01
4750 Insights into Phakopsora pachyrhizi effector-effector interactions
Qi, M.; Yu, H.; Bredow, M.; Chicowski, A. S.; Fields, L. D.; Whitham, S. A.
10.1101/2023.08.30.555440 — plant biology — Posted on 2023-09-01
4751 Colour-analyzer: A new dual colour model-based imaging tool to quantify plant disease
Loranger, M. E. W.; Yim, W.; Accomazzi, V.; Morales Liszcano, N.; Moeder, W.; Yoshioka, K.
10.1101/2023.08.30.555631 — plant biology — Posted on 2023-09-01
4752 Comparative omics reveals unanticipated metabolic rearrangements in a high-oil mutant of plastid acetyl-CoA carboxylase
Kataya, A.; da Silva Nascimento, J. R.; Xu, C.; Garneau, M. G.; Koley, S.; Kimberlin, A. N.; Mooney, B. P.; Allen, D. K.; Bates, P. D.; Koo, A. J.; Xu, D.; Thelen, J. J.
10.1101/2023.08.31.555777 — plant biology — Posted on 2023-09-01
4753 Altered iron-sulfur cluster transfer in Arabidopsis mitochondria reveals lipoyl synthase as a Janus-faced enzyme that generates toxic sulfide
Pedroletti, L.; Moseler, A.; Timm, S.; Poschet, G.; Homagk, M.; The, J. X.; Wagner, S.; Wirtz, M.; Hell, R.; Meyer, A. J.
10.1101/2023.08.30.555573 — plant biology — Posted on 2023-09-01
4756 LRMP inhibits the cAMP-dependence of HCN4 channels by disrupting intramolecular signal transduction
Bankston, J. R.; Proenza, C.; Peters, C. H.; Singh, R. K.; Langley, A. A.; Nichols, W. G.; Ferris, H. R.; Jeffrey, D. A.
10.1101/2023.08.29.555242 — biophysics — Posted on 2023-09-01
4757 Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phages
Caesar, L.; Rice, D. W.; McAfee, A.; Underwood, R.; Tarpy, D. R.; J Foster, L.; Newton, I. L. G.
10.1101/2023.08.29.555332 — genomics — Posted on 2023-09-01
4758 Specific heterotypic interaction promotes asymmetric division of human hematopoietic stem and progenitor cells
Candelas, A.; Vianay, B.; Gelin, M.; Faivre, L.; Larghero, J.; Blanchoin, L.; Thery, M.; Brunet, S.
10.1101/2023.08.31.555706 — cell biology — Posted on 2023-09-01
4759 New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C CDH1:EMI1 complex
Hoefler, A.; Yu, J.; Yang, J.; Zhang, Z.; Chang, L.; Grime, G. W.; Garman, E. F.; Boland, A.; Barford, D.
10.1101/2023.08.31.555674 — cell biology — Posted on 2023-09-01
4760 VCP increases or decreases tau seeding using specific cofactors
Batra, S.; Vaquer-Alicea, J. I.; Manon, V. A.; Kashmer, O. M.; Lemoff, A.; Cairns, N. J.; White, C. L. I.; Diamond, M. I.
10.1101/2023.08.30.555637 — cell biology — Posted on 2023-09-01
4762 Outer mitochondrial membrane E3 Ub ligase MARCH5 controls mitochondrial steps in peroxisome biogenesis.
Karbowski, M.; Verhoeven, N.; Oshima, Y.; Cartier-Zamorano, E.; Neutzner, A.; Boyman, L.
10.1101/2023.08.31.555756 — cell biology — Posted on 2023-09-01
4764 Full-length direct RNA sequencing reveals widespread RNA decay upon cellular stress
Dar, S. A.; Malla, S.; Lee, C. T.-Y.; Martin, J.; Payea, M. J.; Khandeshi, A. J.; Martindale, J. L.; Belair, C.; Maragkakis, M.
10.1101/2023.08.31.555629 — cell biology — Posted on 2023-09-01
4765 Strong paracrine effects of SASP from senescence-induced severe early-onset COPD-derived fibroblasts
Meuleman, R. A.; Timens, W.; Kooistra, W.; van den Berge, M.; Brandsma, C.-A.; Woldhuis, R. R.
10.1101/2023.09.01.555721 — cell biology — Posted on 2023-09-01
4766 Mitosis exit followed by death in interphase prevents the development of polyploid giant cancer cells.
Vicente, J. J.; Khan, K.; Tillinghast, G.; McFaline-Figueroa, J. L.; Sancak, Y.; Stella, N.
10.1101/2023.08.31.555795 — cell biology — Posted on 2023-09-01
4767 Ras-mediated homeostatic control of front-back signaling dictates cell polarity
Lin, Y.; Pal, D. S.; Banerjee, P.; Banerjee, T.; Qin, G.; Deng, Y.; Borleis, J.; Iglesias, P. A.; Devreotes, P.
10.1101/2023.08.30.555648 — cell biology — Posted on 2023-09-01
4769 Phosphorylation bar-coding of Free Fatty Acid receptor 2 is generated in a tissue-specific manner
Barki, N.; Jenkins, L.; Marsango, S.; Dedeo, D.; Bolognini, D.; Dwomoh, L.; Nilsen, M.; Stoffels, M.; Schulz, S.; Nagel, F.; Tobin, A. B.; Milligan, G.
10.1101/2023.09.01.555873 — cell biology — Posted on 2023-09-01
4770 Pre-existing tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia
Mann, Z.; Lim, F.; Verma, S.; Nanavati, B. N.; Davis, J. M.; Begun, J.; Hardeman, E. C.; Gunning, P. W.; Subramanyam, D.; Yap, A. S.; Duszyc, K.
10.1101/2023.08.31.555652 — cell biology — Posted on 2023-09-01
4773 Pathological mutations reveal the key role of the iRhom2 N-terminus for ADAM17 binding, stability and activity.
Bläsius, K.; Ludwig, L.; Knapp, S.; Flasshove, C.; Sonnabend, F.; Keller, D.; Tacken, N.; Gao, X.; Kahveci, S.; Grannemann, C.; Babendreyer, A.; Adrain, C.; Huth, S.; Baron, J.; Ludwig, A.; Düsterhöft, S.
10.1101/2023.08.31.555720 — molecular biology — Posted on 2023-09-01
4778 Functional host-specific adaptation of the intestinal microbiome in hominids
Rühlemann, M. C.; Bang, C.; Gogarten, J. F.; Hermes, B. M.; Groussin, M.; Waschina, S. M.; Poyet, M.; Ulrich, M.; Akoua-Koffi, C.; Deschner, T.; Muyembe-Tamfum, J.-J.; Robbins, M. M.; Surbeck, M.; Wittig, R.; Zuberbühler, K.; Baines, J. F.; Leendertz, F. H.; Franke, A.
10.1101/2023.03.01.530589 — evolutionary biology — Posted on 2023-09-01
4781 Data-driven biomarkers outperform theory-based biomarkers in predicting stroke motor outcomes
Olafson, E.; Sperber, C.; Jamison, K. W.; Bowren, M. D.; Boes, A. D.; Andrushko, J. W.; Borich, M. R.; Boyd, L. A.; Cassidy, J. M.; Conforto, A. B.; Cramer, S. C.; Dula, A. N.; Geranmayeh, F.; Hordacre, B.; Jahanshad, N.; Kautz, S. A.; Lo, B.; Macintosh, B. J.; Piras, F.; Robertson, A. D.; Seo, N. J.; Soekadar, S. R.; Thomopoulos, S. I.; Vecchio, D.; Weng, T. B.; Westlye, L. T.; Winstein, C. J.; Wittenberg, G. F.; Wong, K. A.; Thompson, P. M.; Liew, S.-L.; Kuceyeski, A. F.
10.1101/2023.06.19.545638 — neuroscience — Posted on 2023-09-01
4782 Zooarchaeological investigation of the Hoabinhian exploitation of reptiles and amphibians in Thailand and Cambodia with a focus on the Yellow-headed tortoise (Indotestudo elongata (Blyth, 1854))
Bochaton, C.; Chantasri, S.; Maneechote, M.; Claude, J.; Griggo, C.; Naksri, W.; Forestier, H.; Sophady, H.; Auertrakulvit, P.; Bowonsachoti, J.; Zeitoun, V.
10.1101/2023.04.27.538552 — paleontology — Posted on 2023-09-01
4783 Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane
Morel, C.; Lemerle, E.; Tsai, F.-C.; Obadia, T.; Srivastava, N.; Marechal, M.; Salles, A.; Albert, M.; Stefani, C.; Benito, Y.; Vandenesch, F.; Lamaze, C.; Vassilopoulos, S.; Piel, M.; Bassereau, P.; Gonzalez-Rodriguez, D.; Leduc, C.; Lemichez, E.
10.1101/2022.09.27.509635 — biophysics — Posted on 2023-09-01
4785 Multimodal system for recording individual-level behaviors in songbird groups
Rüttimann, L.; Rychen, J.; Tomka, T.; Hörster, H.; Rocha, M. D.; Hahnloser, R. H.
10.1101/2022.09.23.509166 — animal behavior and cognition — Posted on 2023-09-01
4789 Cellular senescence promotes progenitor cell expansion during axolotl limb regeneration
Yu, Q.; Walters, H.; Pasquini, G.; Singh, S. P.; Lachnit, M.; Oliveira, C.; Perinan, D. L.; Petzold, A.; Kesavan, P.; Subiran, C.; Suner, I. G.; Knapp, D.; Wagner, A.; Bernardos, A.; Alfonso, M.; Nadar, G.; Graf, A. M.; Troyanovskiy, K.; Dahl, A.; Busskamp, V.; Manaez, R.; Yun, M.
10.1101/2022.09.01.506196 — developmental biology — Posted on 2023-09-01
4791 Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART
Blanch-Lombarte, O.; Ouchi, D.; Jimenez-Moyano, E.; Carabelli, J.; Marin, M. A.; Penya, R.; Pelletier, A.; Talla, A.; Sharma, A.; Dalmau, J.; Santos, J. R.; Sekaly, R.-P. A.; Clotet, B.; Prado, J. G.
10.1101/2022.07.13.499924 — immunology — Posted on 2023-09-01
4792 Developmental pyrethroid exposure disrupts molecular pathways for circadian rhythms and synaptic plasticity in mouse brain.
Nguyen, J. H.; Curtis, M. A.; Imami, A. S.; Ryan, W. G.; Alganem, K.; Neifer, K. L.; Nawor, C. N.; Kistler, B. P.; Miller, G. W.; Shukla, R.; McCullumsmith, R. E.; Burkett, J. P.
10.1101/2023.08.28.555113 — neuroscience — Posted on 2023-09-01
4797 The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics
Weber, L. M.; Divecha, H. R.; Tran, M. N.; Kwon, S. H.; Spangler, A.; Montgomery, K. D.; Tippani, M.; Bharadwaj, R.; Kleinman, J. E.; Page, S. C.; Hyde, T. M.; Collado-Torres, L.; Maynard, K. R.; Martinowich, K.; Hicks, S. C.
10.1101/2022.10.28.514241 — neuroscience — Posted on 2023-09-01
4802 Efficient and multiplexed tracking of single cells using whole-body PET/CT
Nguyen, H. T. M.; Das, N.; Wang, Y.; Ruvalcaba, C.; Mehadji, B.; Roncali, E.; Chan, C. K. F.; Pratx, G. J.
10.1101/2023.08.23.554536 — bioengineering — Posted on 2023-09-01
4803 A preclinical model of THC edibles that produces high-dose cannabimimetic responses.
English, A.; Uittenbogaard, F.; Torrens, A.; Sarroza, D.; Slaven, A.; Piomelli, D.; Bruchas, M.; Stella, N.; Land, B. B.
10.1101/2022.11.23.517743 — animal behavior and cognition — Posted on 2023-09-01
4806 Comparative abundance and diversity of populations of the Pseudomonas syringae and Soft Rot Pectobacteriaceae species complexes throughout the Durance River catchment from its French Alps sources to its delta
Morris, C. E.; Lacroix, C.; Chandeysson, C.; Guilbaud, C.; Monteil, C.; Piry, S.; Rochelle-Newall, E.; Fiorini, S.; Van Gijsegem, F.; Barny, M.-A.; Berge, O.
10.1101/2022.09.06.506731 — ecology — Posted on 2023-09-01
4808 LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility
Hwang, J. Y.; Chai, P.; Nawaz, S.; Choi, J.; Lopez-Giraldez, F.; Hussain, S.; Bilguvar, K.; Mane, S.; Lifton, R. P.; Ahmad, W.; Zhang, K.; Chung, J.-J.
10.1101/2023.02.25.530050 — cell biology — Posted on 2023-09-01
4809 The Evolution of Centriole Degradation in Mouse Sperm
Khanal, S.; Jaiswal, A.; Chandanayaka, R.; Puente, N.; Turner, K.; Assefa, K. Y.; Nawras, M.; Back, E. D.; Royfman, A.; Burkett, J.; Cheong, S. H.; Fisher, H. S.; Sindhwani, P.; Gray, J.; Basappa, R. N.; Avidor-Reiss, T.
10.1101/2023.03.11.532086 — cell biology — Posted on 2023-09-01
4811 Insights into the conservation and diversification of the molecular functions of YTHDF proteins
Flores-Tellez, D.; Tankmar, M. D.; von Büllow, S.; Chen, J.; Lindorff-Larsen, K.; Brodersen, P.; Arribas-Hernandez, L.
10.1101/2022.10.19.512826 — molecular biology — Posted on 2023-09-01
4813 Application of a 1H Brain MRS Benchmark Dataset to Deep Learning for Out-of-Voxel Artifacts
Gudmundson, A. T.; Davies-Jenkins, C. W.; Ozdemir, I.; Murali-Manohar, S.; Zollner, H. J.; Song, Y.; Hupfeld, K. E.; Schnitzler, A.; Oeltzschner, G.; Stark, C. E. L.; Edden, R. A. E.
10.1101/2023.05.08.539813 — neuroscience — Posted on 2023-09-01
4815 Systemic Proteome Phenotypes Reveal Defective Metabolic Flexibility in Mecp2 Mutants
Zlatic, S. A.; Werner, E.; Surapaneni, V.; Lee, C. E.; Gokhale, A.; Singleton, K.; Duong, D.; Crocker, A.; Gentile, K.; Middleton, F.; Dalloul, J. M.; Liu, W. L.-Y.; Patgiri, A.; Tarquinio, D.; Carpenter, R.; Faundez, V.
10.1101/2023.04.03.535431 — neuroscience — Posted on 2023-09-01
4816 Role of a Pdlim5:PalmD complex in directing dendrite morphology
Srivastava, Y.; Donta, M.; Mireles, L. L.; Paulucci-Holthauzen, A.; Waxham, M. N.; McCrea, P. D.
10.1101/2023.08.22.553334 — neuroscience — Posted on 2023-09-01