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Archive, 2020-11

4 Analytical validation and performance characteristics of a 48-gene next-generation sequencing panel for detecting potentially actionable genomic alterations in myeloid neoplasms
Rosenthal, S. H.; Gerasimova, A.; Ma, C.; Li, H.-R.; Grupe, A.; Chong, H.; Acab, A.; Smolgovsky, A.; Owen, R.; Elzinga, C.; Chen, R.; Sugganth, D.; Freitas, T.; Graham, J.; Champion, K.; Bhattacharya, A.; Racke, F.; Lacbawan, F.
10.1101/2020.11.30.403634 — cancer biology — Posted on 2020-11-30
5 Genomic surveillance of antimicrobial resistance shows cattle are a moderate source of multi-drug resistant non-typhoidal Salmonella in Mexico
Delgado-Suarez, E. J.; Palos-Guiterrez, T.; Ruiz-Lopez, F. A.; Hernandez Perez, C. F.; Ballesteros-Nova, N. E.; Soberanis-Ramos, O.; Mendez-Medina, R. D.; Allard, M. W.; Rubio-Lozano, M. S.
10.1101/2020.11.30.403618 — genomics — Posted on 2020-11-30
8 Characterization of genetic diversity and population structure within Staphylococcus chromogenes by multilocus sequence Typing
Huebner, R.; Mugabi, R.; Hetesy, G.; Fox, L.; De Vliegher, S.; De Visscher, A.; Barlow, J. W.; Sensabaugh, G.
10.1101/2020.11.30.403683 — microbiology — Posted on 2020-11-30
13 An Optimized CRISPR/Cas9 Approach for Precise Genome Editing in Neurons
FANG, H. L.; Bygrave, A. M.; Roth, R. H.; Johnson, R. C.; Huganir, R. L.
10.1101/2020.11.30.402883 — neuroscience — Posted on 2020-11-30
15 Topical heterogeneity in affective touch: Does it impact body image?
Cazzato, V.; Sacchetti, S.; Shin, S.; Makdani, A.; Trotter, P. D.; McGlone, F.
10.1101/2020.11.30.403600 — neuroscience — Posted on 2020-11-30
18 Empty sella syndrome as a window into the neuroprotective effects of prolactin
Paul, D. A.; Strawderman, E.; Rodriguez, A.; Hoang, R.; Schneider, C.; Haber, S.; Chernoff, B. L.; Shafiq, I.; Williams, Z. R.; Vates, G. E.; Mahon, B. Z.
10.1101/2020.11.30.403576 — neuroscience — Posted on 2020-11-30
19 Creation of an Open Science Dataset from PREVENT-AD, a Longitudinal Cohort Study of Pre-symptomatic Alzheimer's Disease.
Tremblay-Mercier, J.; Madjar, C.; Das, S.; Pichet-Binette, A.; Dyke, S. O. M.; Etienne, P.; Lafaille-Magnan, M.-E.; Remz, J.; Bellec, P.; Collins, D. L.; Rajah, M. N.; Bohbot, V. D.; Leoutsakos, J.-M.; Iturria-Medina, Y.; Kat, J.; Hoge, R. D.; Gauthier, S.; Tardif, C.; Chakravarty, M. M.; Poline, J.-B.; Rosa-Neto, P.; Evans, A. C.; Villeneuve, S.; Poirier, J.; Breitner, J. C. S.; the PREVENT-AD Research Group,
10.1101/2020.03.04.976670 — neuroscience — Posted on 2020-11-30
21 Bacteriological and histopathological findings in cetaceansthat stranded in the Philippines from 2017 to 2018
Obusan, M. C.; Caras, J. A. C.; Lumang, L. S. L.; Calderon, E. J. S.; Villanueva, R. M. D.; Salibay, C. C.; Siringan, M. A. T.; Rivera, W. L.; Masangkay, J. S.; Aragones, L. V.
10.1101/2020.11.30.403568 — zoology — Posted on 2020-11-30
26 Multiple binding sites for resin-acid derivatives on the voltage-sensor domain of the Shaker potassium channel
Silvera Ejneby, M.; Gromova, A.; Ottosson, N. E.; Borg, S.; Estrada-Mondragon, A.; Yazdi, S.; Apostolakis, P.; Elinder, F.; Delemotte, L.
10.1101/2020.06.11.146548 — biophysics — Posted on 2020-11-30
29 Association between the extent of DNA methylation at the CpG sites of HIF3A and parameters of obesity in the general Japanese population
Mizuno, G.; Yamada, H.; Munetsuna, E.; Yamazaki, M.; Ando, Y.; Fujii, R.; Tsuboi, Y.; Teshigawara, A.; Kageyama, I.; Osakabe, K.; Sugimoto, K.; Ishikawa, H.; Ichino, N.; Ohta, Y.; Ohashi, K.; Hashimoto, S.; Suzuki, K.; Koji Suzuki,
10.1101/2020.11.30.403709 — biochemistry — Posted on 2020-11-30
34 No change in oxytocin level before a human intergroup competition: study among Polish players before rugby and handball matches
Koziel, S.; Kociuba, M.; Ignasiak, Z.; Rokita, A.; Cichy, I.; Dutkowski, A.; Scislak, M.; Kochan, K.; Sebastjan, A.; Spinek, A.; Lorek, D.; Chakraborty, R.; Bogin, B.
10.1101/2020.11.30.403592 — evolutionary biology — Posted on 2020-11-30
36 BUB-1 targets PP2A:B56 to regulates chromosome congression during meiosis I in C. elegans oocytes
Bel Borja, L.; Soubigou, F.; Taylor, S. J. P.; Fraguas Bringas, C.; Budrewicz, J.; Lara-Gonzalez, P.; Sorensen Turpin, C. G.; Bembenek, J. N.; Cheerambathur, D. K.; Pelisch, F.
10.1101/2020.06.12.148254 — cell biology — Posted on 2020-11-30
37 The first AI-based mobile application for antibiotic resistance testing
Pascucci, M.; Royer, G.; Adamek, J.; Aristizabal, D.; Bezzarga, A.; Blanche, L.; Boniface-Chang, G.; Brunner, A.; Curel, C.; Dulac-Arnold, G.; Malou, N.; Nordon, C.; Runge, V.; Samson, F.; Sebastian, E.; Soukieh, D.; Vert, J.-P.; Ambroise, C.; Madoui, M.-A.
10.1101/2020.07.23.216929 — microbiology — Posted on 2020-11-30
40 Ethanol's action at BK channels accelerates the transition from moderate to excessive alcohol consumption
Okhuarobo, A.; Kreifeldt, M.; Bhattacharyya, P.; Dopico, A. M.; Roberts, A. J.; Homanics, G. E.; Contet, C.
10.1101/2020.10.29.360107 — neuroscience — Posted on 2020-11-30
43 Rapid Cortical Adaptation and the Role of Thalamic Synchrony During Wakefulness
Wright, N. C.; Borden, P. Y.; Liew, Y. J.; Bolus, M. F.; Stoy, W. M.; Forest, C. R.; Stanley, G. B.
10.1101/2020.10.08.331660 — neuroscience — Posted on 2020-11-30
44 Anatomy and activity patterns in a multifunctional motor neuron and its surrounding circuits
Ashaber, M.; Tomina, Y.; Kassraian-Fard, P.; Bushong, E. A.; Kristan, W. B.; Ellisman, M. H.; Wagenaar, D. A.
10.1101/2020.03.09.984013 — neuroscience — Posted on 2020-11-30
51 Membrane Env liposomes for immunization with HIV spikes
Leaman, D. P.; Stano, A.; Chen, Y.; Zhang, L.; Zwick, M. B.
10.1101/2020.11.29.403204 — immunology — Posted on 2020-11-30
52 A Neutralizing Antibody-Conjugated Photothermal Nanoparticle Captures and Inactivates SARS-CoV-2
Cai, X.; Prominski, A.; Lin, Y.; Ankenbruck, N.; Rosenberg, J.; Chen, M.; Shi, J.; Chang, E. B.; Penaloza-MacMaster, P.; Tian, B.; Huang, J.
10.1101/2020.11.30.404624 — bioengineering — Posted on 2020-11-30
53 Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain
Wu, C.; Qavi, A. J.; Hachim, A.; Kavian, N.; Cole, A. R.; Moyle, A. B.; Wagner, N. D.; Sweeney-Gibbons, J.; Rohrs, H. W.; Gross, M. L.; Peiris, J. S. M.; Basler, C. F.; Farnsworth, C. W.; Valkenburg, S. A.; Amarasinghe, G. K.; Leung, D. W.
10.1101/2020.11.30.404905 — biochemistry — Posted on 2020-11-30
55 The Erythropoietin Receptor Stimulates Rapid Cycling and Formation of Larger Red Cells During Mouse and Human Erythropoiesis
Hidalgo, D.; Bejder, J.; Pop, R.; Gellatly, K.; Scalf, S. M.; Eastman, A. E.; Chen, J.-J.; Zhu, J. L.; Heuberger, J. A. A. C.; Guo, S.; Koury, M. J.; Nordsborg, N. B.; Socolovsky, M.
10.1101/2020.11.30.404780 — developmental biology — Posted on 2020-11-30
56 Deletion of INPP5E in the murine retina impairs axoneme formation and prevents photoreceptor disc morphogenesis
Sharif, A.; Gerstner, C. D.; Cady, M. A.; Arshavsky, V. Y.; Mitchell, C. A.; Ying, G.; Frederick, J. M.; Baehr, W.
10.1101/2020.11.29.403030 — neuroscience — Posted on 2020-11-30
58 Understanding the Evolutionary Games in NSCLC Microenvironment
Bhattacharya, R.; Velde, R. V.; Marusyk, V.; Desai, B.; Kaznatcheev, A.; Marusyk, A.; Basanta, D.
10.1101/2020.11.30.404350 — cancer biology — Posted on 2020-11-30
61 The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality
Issaian, A.; Hay, A.; Dzieciatkowska, M.; Roberti, D.; Perrotta, S.; Darula, Z.; Redzic, J. S.; Busch, M. P.; Page, G. P.; Hansen, K.; Eisenmesser, E. Z.; Zimring, J. C.; D'Alessandro, A.
10.1101/2020.11.30.404756 — biochemistry — Posted on 2020-11-30
63 H3K4 trimethylation is required for postnatal pancreatic endocrine cell functional maturation
Campbell, S. A.; Begin, J.; McDonald, C. L.; Vanderkruk, B.; Stephan, T. L.; Hoffman, B. G.
10.1101/2020.11.29.402990 — developmental biology — Posted on 2020-11-30
64 p38-MAPK mediated rRNA processing and translation regulation enables PrE differentiation during mouse blastocyst maturation.
Bora, P.; Gahurova, L.; Masek, T.; Hauserova, A.; Potesil, D.; Jansova, D.; Susor, A.; Zdrahal, Z.; Ajduk, A.; Pospisek, M.; Bruce, A. W.
10.1101/2020.11.30.403931 — developmental biology — Posted on 2020-11-30
68 Consequences of human cytomegalovirus infection on small extracellular vesicles isolated from first trimester placental histocultures
Bergamelli, M.; Martin, H.; Benard, M.; Ausseil, J.; Mansuy, J.-M.; Hurbain, I.; Mouysset, M.; Groussolles, M.; Cartron, G.; Tanguy le Gac, Y.; Moinard, N.; Suberbielle, E.; Izopet, J.; Tscherning, C.; Raposo, G.; Gonzalez-Dunia, D.; d'Angelo, G.; Malnou, C. E.
10.1101/2020.11.30.402693 — cell biology — Posted on 2020-11-30
69 Remodeling and activation mechanisms of outer arm dynein revealed by cryo-electron microscopy
Kubo, S.; Yang, S. K.; Black, C.; Dai, D.; Valente, M.; Gaertig, J.; Ichikawa, M.; Bui, K. H.
10.1101/2020.11.30.404319 — cell biology — Posted on 2020-11-30
71 Loss of a subunit of vacuolar ATPase identifies unexpected biological signatures of reduced organelle acidification in vivo
Pottie, L.; Van Gool, W.; Vanhooydonck, M.; Hanisch, F.-G.; Goeminne, G.; Rajkovic, A.; Coucke, P.; Sips, P.; Callewaert, B.
10.1101/2020.11.30.397463 — molecular biology — Posted on 2020-11-30
74 Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles
Brouwer, P. J. M.; Antanasijevic, A.; de Gast, M.; Allen, J. D.; Allen, J. D.; Bijl, T. P. L.; Yasmeen, A.; Ravichandran, R.; Burger, J.; Ozorowski, G.; Torres, J. L.; LaBranche, C.; Montefiori, D.; Ringe, R. P.; van Gils, M.; Moore, J. P.; Klasse, P. J.; Crispin, M.; King, N. P.; Ward, A.; Sanders, R. W.
10.1101/2020.11.30.403543 — microbiology — Posted on 2020-11-30
75 Emetine as an antiviral agent suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E: An in vitro study
Kumar, R.; Khandelwal, N.; Chander, Y.; Riyesh, T.; Gulati, B. R.; Pal, Y.; Tripathi, B. N.; Barua, S.; Kumar, N.
10.1101/2020.11.29.401984 — microbiology — Posted on 2020-11-30
81 A Novel SARS-CoV-2 Multitope Protein/Peptide Vaccine Candidate is Highly Immunogenic and Prevents Lung Infection in an Adeno Associated Virus Human Angiotensin-Converting Enzyme 2 (AAV hACE2) Mouse Model
Guirakhoo, F.; Kuo, L.; Peng, J.; Huang, J. H.; Kuo, B.; Lin, F.; Liu, K.; Liu, Z.; Wu, G.; Ding, S.; Hou, L.-L.; Cheng, J.; Yang, V.; Jiang, H.; Wang, J.; Chen, T.; Xia, W.; Lin, E.; Hung, C. H.; Chen, K.; Shih, Z.; Lin, Y.; Schurter, B. T.; Hu, M. M.; Heppner, G.; Malherbe, D. C.; Bukreyev, A.; Hellerstein, M.; Monath, T.; Wang, C. Y.
10.1101/2020.11.30.399154 — immunology — Posted on 2020-11-30
84 Gating mechanism of cardiac ryanodine receptor 2 upon calcium ion binding
Ogawa, H.; Murayama, T.; Kobayashi, T.; Kurebayashi, N.; Saito, K.; Sakurai, T.; Kodama, M.; Tsutsumi, A.; Kikkawa, M.
10.1101/2020.11.30.401026 — biochemistry — Posted on 2020-11-30
86 The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions
Pichon, X.; Moissoglu, K.; Coleno, E.; Wang, T.; Imbert, A.; Peter, M.; Chouaib, R.; Walter, T.; Mueller, F.; Zibara, K.; Bertrand, E.; Mili, S.
10.1101/2020.11.30.403394 — cell biology — Posted on 2020-11-30
87 Recombinant Fc-fusion vaccine of RBD induced protection against SARS-CoV-2 in non-human primate and mice
Sun, Y.; Han, G.; Wei, W.; Hu, Z.; Sun, S.; He, L.; Zhao, Z.; Gu, H.; Wang, T.; Yang, X.; Chen, S.; Deng, Y.; Li, J.; Zhao, J.; Li, L.; Li, X.; He, P.; Li, G.; Li, H.; Gao, C.; Lang, X.; Geng, S.; Wang, X.; Fei, G.; Li, Y.; Gao, Y.; Fang, X.; Zhao, Y.
10.1101/2020.11.29.402339 — immunology — Posted on 2020-11-30
88 The tumor suppressor protein PTEN undergoes amyloid-like aggregation in tumor cells.
Claes, F.; Maritschnegg, E.; De Baets, G.; Siekierska, A.; Saiz Rubio, M.; Ramakers, M.; Michiels, E.; De Smet, F.; Depreeuw, J.; Vergote, I.; Vanderstichele, A.; van den Broeck, A.; Olbrecht, S.; Hermans, E.; Amant, F.; Lambrechts, D.; Nilsson, P. R.; Rousseau, F.; Schymkowitz, J.
10.1101/2020.11.30.402115 — cancer biology — Posted on 2020-11-30
89 First computational design of Covid-19 coronavirus vaccine using lambda superstrings
Martinez, L.; Malaina, I.; Salcines, D.; Teran, H.; Alegre, S.; MartInez de la Fuente, I.; Gonzalez, E.; Ocejo, G.; Alvarez, C.
10.1101/2020.11.30.403824 — bioinformatics — Posted on 2020-11-30
90 Isolation, spectral characterization and biological activity of fractions of the flavonoid-containing Gratiola officinalis L. extract
Shirokov, A.; Grinev, V.; Polukonova, N.; Verkhovsky, R.; Doroshenko, A.; Mudrak, D.; Navolokin, N.; Polukonova, A.; Bucharskaya, A.; Maslyakova, G.
10.1101/2020.11.30.404475 — biochemistry — Posted on 2020-11-30
92 Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
Chen, X.; Ali, Y.; Fisher, C. E. L.; Arribas-Bosacoma, R.; Rajasekaran, M. B.; Williams, G.; Walker, S.; Roe, S. M.; Pearl, L. H.; Ward, S. E.; Pearl, F. M. G.; Oliver, A. W.
10.1101/2020.11.30.403493 — biochemistry — Posted on 2020-11-30
94 Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation.
Thompson, A. D.; Helms, A. S.; Kannan, A.; Job, J.; Lakdawala, N. K.; Wittekind, S. G.; Pereira, A.; Jacoby, D. L.; Colan, S. D.; Ashley, E. A.; Saberi, S.; Ware, J. S.; Ingles, J.; Semsarian, C.; Michels, M.; Mazzarotto, F.; Olivotto, I.; Ho, C. Y.; Day, S. M.
10.1101/2020.11.29.402974 — genetics — Posted on 2020-11-30
95 Hypothalamic glucocorticoid receptor in CRF neurons is essential for HPA axis habituation to repeated stressor
Dournes, C.; Dine, J.; Lopez, J.-P.; Brivio, E.; Anderzhanova, E.; Roeh, S.; Kuehne, C.; Holzapfel, M.; Huettl, R.-E.; Stoffel, R.; Tietze, L.; Eggert, C.; Schieven, M.; Jakovcevski, M.; Deussing, J. M.; Chen, A.
10.1101/2020.11.30.402024 — neuroscience — Posted on 2020-11-30
98 FcγR responses to soluble immune complexes of varying size: A scalable cell-based reporter system
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2020-11-30
101 Oligodendrocytes support axonal transport and maintenance via exosome secretion
Frühbeis, C.; Kuo-Elsner, W. P.; Mueller, C.; Barth, K.; Peris, L.; Tenzer, S.; Möbius, W.; Werner, H.; Nave, K.-A.; Fröhlich, D.; Krämer-Albers, E.-M.
10.1101/2019.12.20.884171 — neuroscience — Posted on 2020-11-30
103 Sex Differences in MRI-Based Metrics of Glioma Invasion and Brain Mechanics
Anderies, B. J.; Yee, S. F.; Jackson, P. R.; Rickertsen, C. R.; Hawkins-Daarud, A. J.; Johnston, S. K.; Clark-Swanson, K. R.; Hoxworth, J. M.; Le, Y.; Zhou, Y.; Pepin, K. M.; Massey, S. C.; Hu, L. S.; Huston, J. R.; Swanson, K. R.
10.1101/2020.11.21.352724 — biophysics — Posted on 2020-11-30
105 Cell Layers: Uncovering clustering structure and knowledge in unsupervised single-cell transcriptomic analysis
Blair, A.; Hu, R. K.; Farah, E. N.; Pollard, K. S.; Przytycki, P. F.; Kathiriya, I. S.; Bruneau, B. G.
10.1101/2020.11.29.400614 — bioinformatics — Posted on 2020-11-30
110 Evolutionary drivers of polymorphic sexual signals in slender anoles
Prates, I.; D'Angiolella, A. B.; Rodrigues, M. T.; Melo-Sampaio, P. R.; de Queiroz, K.; Bell, R. C.
10.1101/2020.11.29.402784 — evolutionary biology — Posted on 2020-11-30
112 DNA methylation study of age and sex in baboons and four other primates
Horvath, S.; Haghani, A.; Zoller, J. A.; Ernst, J.; Pellegrini, M.; Jasinska, A. J.; Mattison, J. A.; Raj, K.; Salmon, A. B.; Jenkins, S.; Li, C.; Nathanielsz, P. W.
10.1101/2020.11.29.402891 — developmental biology — Posted on 2020-11-30
119 High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism
Parlakgul, G.; Arruda, A. P.; Cagampan, E.; Pang, S.; Guney, E.; Lee, Y.; Hess, H. F.; Xu, C. S.; Hotamisligil, G. S.
10.1101/2020.11.18.387803 — cell biology — Posted on 2020-11-30
120 Apoptosis, G1 phase stall and premature differentiation account for low chimeric competence of Human and rhesus monkey naive pluripotent stem cells
Aksoy, I.; Rognard, C.; Moulin, A.; Marcy, G.; Masfaraud, E.; Wianny, F.; Cortay, V.; Bellemin-Menard, A.; Doerflinger, N.; Dirheimer, M.; Mayere, C.; Lynch, C.; Raineteau, O.; Joly, T.; Dehay, C.; Serrano, M.; Afanassieff, M.; Savatier, P.
10.1101/2020.03.27.011890 — cell biology — Posted on 2020-11-30
122 Accelerated Predictive Healthcare Analytics with Pumas, A High Performance Pharmaceutical Modeling and Simulation Platform
Rackauckas, C. V.; Ma, Y.; Noack, A.; Dixit, V.; Mogensen, P.; Byrne, S.; Maddhashiya, S.; Calderon, J. B. S.; Nyberg, J.; Gobburu, J.; Ivaturi, V.
10.1101/2020.11.28.402297 — pharmacology and toxicology — Posted on 2020-11-30
123 Epithelial colonies in vitro elongate through collective effects
Comelles, J.; Soumya, S. S.; Lu, L.; Le-Maout, E.; Anvitha, S.; Salbreux, G.; Jülicher, F.; Inamdar, M. M.; Riveline, D.
10.1101/755181 — biophysics — Posted on 2020-11-30
125 FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs
Griffith, B. G. C.; Upstill-Goddard, R.; Brunton, H.; Grimes, G. R.; Biankin, A. V.; Serrels, B.; Byron, A.; Frame, M. C.
10.1101/2020.07.15.177212 — genomics — Posted on 2020-11-30
126 Rapid molecular evolution of Spiroplasma symbionts of Drosophila
Gerth, M.; Martinez Montoya, H.; Ramirez, P.; Masson, F.; Griffin, J. S.; Aramayo, R.; Siozios, S.; Lemaitre, B.; Mateos, M.; Hurst, G. D.
10.1101/2020.06.23.165548 — evolutionary biology — Posted on 2020-11-30
129 Global architecture of the nucleus in single cells by DNA seqFISH+ and multiplexed immunofluorescence
Takei, Y.; Yun, J.; Ollikainen, N.; Zheng, S.; Pierson, N.; White, J.; Shah, S.; Thomassie, J.; Eng, C.-H. L.; Guttman, M.; Yuan, G.-C.; Cai, L.
10.1101/2020.11.29.403055 — systems biology — Posted on 2020-11-30
130 Mapping the Cellular Origin and Early Evolution of Leukemia in Down Syndrome
Wagenblast, E.; Araujo, J.; Gan, O. I.; Cutting, S. K.; Murison, A.; Krivdova, G.; Azkanaz, M.; McLeod, J. L.; Smith, S. A.; Marhon, S. A.; Gabra, M.; Chan-Seng-Yue, M.; Garcia-Prat, L.; Salmena, L.; De Carvalho, D. D. D.; Chong, K.; Roifman, M.; Shannon, P.; Wang, J. C. Y.; Hitzler, J. K.; Chitayat, D.; Dick, J. E.; Lechman, E. R.
10.1101/2020.11.29.402800 — cancer biology — Posted on 2020-11-30
132 Computational optical sectioning by phase-space imaging with an incoherent multiscale scattering model
Zhang, Y.; Lu, Z.; Wu, J.; Lin, X.; Jiang, D.; Cai, Y.; Xie, J.; Zhu, T.; Ji, X.; Dai, Q.
10.1101/2020.11.29.402958 — cell biology — Posted on 2020-11-30
133 Integrative Analysis of Phenomic, Genomic, and Transcriptomic to Identify Potential Functional Genes of Yaks in Plain and Plateau
Wang, J.; Guan, J.; Yixi, K.; Shu, T.; Chai, Z.; Wang, J.; Wang, H.; Wu, Z.; Cai, X.; Zhong, J.; Luo, X.
10.1101/2020.11.29.392167 — genomics — Posted on 2020-11-30
134 The molecular logic of synaptic wiring at the single cell level
Lohmann, I.; Velten, J.; Agarwal, R.; van Nierop y Sanchez, P.; Bognar, L.; Paulsen, M.; Velten, L.
10.1101/2020.11.30.402057 — developmental biology — Posted on 2020-11-30
135 Central Neural Regulation of Parathyroid Hormone
Zhang, L.; Liu, N.; Shao, J.; Gao, D.; Liu, Y.; Chen, D.; Wang, L.; Lu, W. W.; Yang, F.
10.1101/2020.11.30.403279 — neuroscience — Posted on 2020-11-30
138 Non-invasive surveys of mammalian viruses using environmental DNA
Alfano, N.; Dayaram, A.; Axtner, J.; Tsangaras, K.; Kampmann, M.-L.; Mohamed, A.; Wong, S. T.; Gilbert, M. T. P.; Wilting, A.; Greenwood, A. D.
10.1101/2020.03.26.009993 — molecular biology — Posted on 2020-11-30
142 Design of proteins presenting discontinuous functional sites using deep learning
Tischer, D.; Lisanza, S.; Wang, J.; Dong, R.; Anishchenko, I. K.; Milles, L.; Ovchinnikov, S.; Baker, D.
10.1101/2020.11.29.402743 — biochemistry — Posted on 2020-11-29
143 Identification of herboxidiene features that mediate conformation-dependent SF3B1 interactions to inhibit splicing.
Gamboa Lopez, A.; Allu, S. R.; Mendez, P.; Reddy, G. C.; Maul-Newby, H. M.; Ghosh, A. K.; Jurica, M. S.
10.1101/2020.11.18.387712 — molecular biology — Posted on 2020-11-29
146 Altered functional integration of brain activity is a marker of impaired cognitive performance following sleep deprivation
Cross, N.; Pomares, F. B.; Nguyen, A.; Perrault, A. A.; Jegou, A.; Uji, M.; Lee, K.; Razavipour, F.; Ali, O. B. K.; Aydin, U.; Benali, H.; Grova, C.; Dang-Vu, T. T.
10.1101/2020.11.28.402305 — neuroscience — Posted on 2020-11-29
148 Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis
Fujihara, K. M.; Zhang, B. Z.; Jackson, T. D.; Nijagal, B.; Ang, C.-S. M.; Nikolic, I.; Sutton, V.; Trapani, J.; Simpson, K. J.; Stojanovski, D.; Leimkuehler, S.; Haupt, S.; Phillips, W. A.; Clemons, N. J.
10.1101/2020.11.29.398867 — cancer biology — Posted on 2020-11-29
151 Bioelectrical Interfaces with Cortical Spheroids in Three-Dimensions
Kalmykov, A.; Reddy, J. W.; Bedoyan, E.; Wang, Y.; Garg, R.; Rastogi, S. K.; Cohen-Karni, D.; Chamanzar, M.; Cohen-Karni, T.
10.1101/2020.11.29.401638 — bioengineering — Posted on 2020-11-29
153 Microfluidic Device Facilitates Novel In Vitro Modeling of Human Neonatal Necrotizing Enterocolitis-on-a-Chip
Lanik, W. E.; Luke, C. J.; Nolan, L. S.; Gong, Q.; Rimer, J. M.; Gale, S. E.; Luc, R.; Bidani, S. S.; Sibald, C. A.; Lewis, A. N.; Mihi, B.; Agrawal, P.; Goree, M.; Maestas, M.; Hu, E.; Peters, D. G.; Good, M.
10.1101/2020.11.29.402735 — cell biology — Posted on 2020-11-29
154 The nature of mitotic forces in epithelial monolayers
Gupta, V. K.; Nam, S.; Camuglia, J.; Martin, J. L.; Sanders, E. N.; O'Brien, L. E.; Martin, A. C.; Kim, T.; Chaudhuri, O.
10.1101/2020.11.16.378927 — cell biology — Posted on 2020-11-29
155 Papillary And Reticular Fibroblasts Generate Distinct Microenvironments That Differentially Impact Angiogenesis
Mauroux, A.; Joncour, P.; Gillet, B.; Hugues, S.; Ardidie-Robouant, C.; Marchand, L.; Liabotis, A.; Mailly, P.; Monnot, C.; Germain, S.; Bordes, S.; Closs, B.; Ruggiero, F.; Muller, L.
10.1101/2020.11.29.402594 — cell biology — Posted on 2020-11-29
157 Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection
Kamel, W.; Noerenberg, M.; Cerikan, B.; Chen, H.; Järvelin, A. I.; Kammoun, M.; Lee, J.; Shuai, N.; Garcia-Moreno, M.; Andrejeva, A.; Deery, M. J.; Neufeldt, C. J.; Cortese, M.; Knight, M. L.; Lilley, K. S.; Martinez, J.; Davis, I.; Bartenschlager, R.; Mohammed, S.; Castello, A.
10.1101/2020.11.25.398008 — microbiology — Posted on 2020-11-29
158 Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen
Bender, N. G.; Khare, P.; Martinez, J.; Tweedell, R. E.; Nyasembe, V. O.; Lopez-Gutierrez, B.; Tripathi, A.; Miller, D.; Hamerly, T.; Vela, E. M.; Howard, R. F.; Nsango, S.; Cobb, R. R.; Harbers, M.; Dinglasan, R. R.
10.1101/2020.11.29.402669 — immunology — Posted on 2020-11-29
159 Action Observation Network activity related to object-directed and socially directed actions in Adolescents
Lesourd, M.; Afyouni, A.; Geringswald, F.; Cignetti, F.; Raoul, L.; Sein, J.; Nazarian, B.; Anton, J.-L.; Grosbras, M.-H.
10.1101/2020.11.29.402560 — neuroscience — Posted on 2020-11-29
161 Crop-photoperiodism model 2.0 for the panicle-initiation date of sorghum and rice that includes daily changes in sunrise and sunset times
Clerget, B.; Sidibe, M.; Bueno, C. S.; Trouche, G.; Chantereau, J.; Grenier, C.; Kawakata, T.; Domingo, A. J.; Layaoen, H. L.; Palacios, N. G.; Bernal, J. H.
10.1101/2020.11.29.402628 — plant biology — Posted on 2020-11-29
162 VGLL1-directed TEAD activation drives endocrine therapy resistance in estrogen receptor positive breast cancer
Gemma, C.; Singh, A.; Belfiore, A.; Lai, C.; Periyasamy, M.; Abuelmaaty, S.; Davies, C.; Wang, X.; Simmons, G.; Nguyen, V.; Magnani, L.; Rakha, E.; Martin, L.-A.; Coombes, C.; Pruneri, G.; Buluwela, L.; Ali, S.
10.1101/2020.11.29.402842 — cancer biology — Posted on 2020-11-29
163 Seeing the forest through the trees: Identifying functional interactions from Hi-C
Liu, N.; low, w. y.; Alinejad-Rokny, H.; Sadlon, T.; Pederson, S. M.; Barry, S. C.; Breen, J.
10.1101/2020.11.29.402420 — bioinformatics — Posted on 2020-11-29
164 Estimating the timing of HIV infection from unmutated sequences
Pankow, A.; Christian, M.; Smith, N.; Sheward, D. J.; Murrell, B.
10.1101/2020.11.28.402271 — bioinformatics — Posted on 2020-11-29
165 Differentiation of human induced pluripotent stem cells into functional airway epithelium
Ahmed, E.; Fieldes, M.; Bourguignon, C.; Mianne, J.; Petit, A.; Vernisse, C.; Jory, M.; Cazevieille, C.; Boukhaddaoui, H.; Garnett, J. P.; Massiera, G.; Vachier, I.; Assou, S.; Bourdin, A.; De Vos, J.
10.1101/2020.11.29.400358 — bioengineering — Posted on 2020-11-29
166 Performance comparison: exome-sequencing as a single test replacing Sanger-sequencing
Fridman, H.; Bormans, C.; Einhorn, M.; Au, D.; Bormans, A.; Porat, Y.; Sanchez, L. F.; Manning, B.; Levy-Lahad, E.; Behar, D. M.
10.1101/2020.11.29.400853 — genetics — Posted on 2020-11-29
167 Variant Curation Expert Panel Recommendations for RYR1 Pathogenicity Assertions in Malignant Hyperthermia Susceptibility
Johnston, J. J.; Dirksen, R. T.; Girard, T.; Gonsalves, S. G.; Hopkins, P. M.; Riazi, S.; Saddic, L. A.; Sambuughin, N.; Saxena, R.; Stowell, K.; Weber, J.; Rosenberg, H.; Biesecker, L. G.
10.1101/2020.11.29.402768 — genetics — Posted on 2020-11-29
169 CSF1R-dependent macrophages control postnatal somatic growth and organ maturation.
Keshvari, s.; Caruso, M.; Batoon, L.; Sehgal, A.; Teakle, N.; Patkar, O.; Chen, C.; Snell, C. E.; Stevenson, A.; Davis, F. M.; Bush, S. J.; Pridans, C.; Summers, K. M.; Irvine, K. M.; Hume, D. A.
10.1101/2020.11.29.402859 — developmental biology — Posted on 2020-11-29
171 Amplicon and metagenomic analysis of MERS-CoV and the microbiome in patients with severe Middle East respiratory syndrome (MERS)
Aljabr, W.; Alruwaili, M.; Penrice-Randal, R.; Alrezaihi, A.; Harrison, A. J.; Ryan, Y.; Bentley, E.; Jones, B.; Alhatlani, B. Y.; AlShahrani, D.; Mahmood, Z.; Rickett, N. J.; Alosaimi, B.; Naeem, A.; Alamri, S.; Alsran, H.; Hamed, M. E.; Dong, X.; Assiri, A.; Alrasheed, A.; Hamza, M.; Carroll, M. W.; Gemmell, M.; Darby, A.; Donovan-Banfield, I.; Stewart, J. P.; Matthews, D. A.; Davidson, A. D.; Hiscox, J. A.
10.1101/2020.11.28.400671 — molecular biology — Posted on 2020-11-29
180 Demographics and Employment of Max-Planck Society's Postdocs
Vallier, M.; Mueller, M.; Alcami, P.; Bellucci, G.; Grange, M.; Lu, Y.-X.; Duponchel, S.
10.1101/2020.11.27.399733 — scientific communication and education — Posted on 2020-11-29
181 Bringing BOS to light: Uncovering the key enzyme in the biosynthesis of the neurotoxin β-ODAP in Grass Pea (Lathyrus sativus L.)
Goldsmith, M.; Barad, S.; Knafo, M.; Savidor, A.; Ben-Dor, S.; Brandis, A.; Mehlman, T.; Peleg, Y.; Albeck, S.; Dym, O.; Benzeev, E.; Reich, Z.
10.1101/2020.11.29.402396 — plant biology — Posted on 2020-11-29
182 SLC7A11 is a superior determinant of APR-246 (Eprenetapopt) response than TP53 mutation status
Fujihara, K. M.; Corrales-Benitez, M.; Cabalag, C. S.; Zhang, B. Z.; Ko, H. S.; Liu, D. S.; Simpson, K. J.; Haupt, Y.; Haupt, S.; Phillips, W. A.; Clemons, N. J.
10.1101/2020.11.29.398875 — cancer biology — Posted on 2020-11-29
183 Predicting and validating protein degradation in proteomes using deep learning
Ozols, M.; Eckersley, A.; Platt, C.; Mcguinness, C. S.; Hibbert, S.; Revote, J.; Li, F.; Griffiths, C.; Watson, R.; Song, J.; Bell, M.; Sherratt, M.
10.1101/2020.11.29.402446 — bioinformatics — Posted on 2020-11-29
188 Regulating enzymatic reactions in Escherichia coli utilizing light-responsive cellular compartments based on liquid-liquid phase separation
Huang, Z.; Sun, L.; Lu, G.; Liu, H.; Zhai, Z.; Feng, S.; Gao, J.; Chen, C.; Qing, C.; Fang, M.; Chen, B.; Fu, J.; Wang, X.; Chen, G.-Q.
10.1101/2020.11.26.395616 — synthetic biology — Posted on 2020-11-29
191 Whole slide imaging is a high-throughput method to assess Candida biofilm formation
Raas, M. W. D.; Silva, T. P.; Freitas, J. O. C.; Campos, L. M.; Fabri, R. L.; Melo, R. C.
10.1101/2020.03.15.992735 — microbiology — Posted on 2020-11-29
192 Predicting and validating protein degradation in proteomes using deep learning
Ozols, M.; Eckersley, A.; Platt, C.; Mcguinness, C. S.; Hibbert, S.; Revote, J.; Li, F.; Griffiths, C.; Watson, R.; Song, J.; Bell, M.; Sherratt, M.
10.1101/2020.11.29.402446 — bioinformatics — Posted on 2020-11-29
195 Rare Genetic Variation Underlying Human Diseases and Traits: Results from 200,000 Individuals in the UK Biobank
Jurgens, S. J.; Choi, S. H.; Morrill, V. N.; Chaffin, M.; Pirruccello, J. P.; Halford, J. L.; Weng, L.-C.; Nauffal, V.; Roselli, C.; Hall, A. W.; Aragam, K.; Lunetta, K. L.; Lubitz, S. A.; Ellinor, P. T.
10.1101/2020.11.29.402495 — genetics — Posted on 2020-11-29
196 First demonstration of the FLASH effect with ultrahigh dose-rate high energy X-rays
Gao, F.; Yang, Y.; Zhu, H.; Wang, J.; Xiao, D.; Zhou, Z.; Dai, T.; Zhang, Y.; Feng, G.; Li, J.; Lin, B.; Xie, G.; Ke, Q.; Li, P.; Sheng, X.; Wang, H.; Yan, L.; Lao, C.; Li, M.; Lu, Y.; Zhao, J.; Feng, S.; Du, X.; Wu, D.
10.1101/2020.11.27.401869 — cancer biology — Posted on 2020-11-29
197 A highly contiguous genome assembly of a major forest pest, the Eurasian spruce bark beetle Ips typographus
Powell, D.; Grosse-Wilde, E.; Krokene, P.; Roy, A.; Chakraborty, A.; Lofstedt, C.; Vogel, H.; Andersson, M. N.; Schlyter, F.
10.1101/2020.11.28.401976 — genomics — Posted on 2020-11-29
198 A fish-specific new gene evolves new functions in cichlid fishes
Gu, L.; Li, C.; Mao, X.; Wei, Z.; Huang, Y.; He, X.; Zhou, W.; Li, L.; Wang, D.
10.1101/2020.11.28.391342 — evolutionary biology — Posted on 2020-11-29
200 Broadening the ecology of fear: non-lethal effects arise from diverse responses to predation and parasitism
Daversa, D. R.; Hechinger, R. F.; Madin, E.; Fenton, A.; Dell, A. I.; Ritchie, E.; Rohr, J.; Rudolph, V. H. W.
10.1101/766477 — ecology — Posted on 2020-11-29
201 Genetic basis for the essentiality of a bacterial anti-sigma factor involved in virulence
Schofield, M. C.; Rodriguez, D.; Kidman, A. A.; Michaels, L. A.; Campbell, E. A.; Jorth, P. A.; Tseng, B. S.
10.1101/2020.08.17.253617 — microbiology — Posted on 2020-11-29
202 Pfcerli2, a duplicated gene in the malaria parasite Plasmodium falciparum essential for invasion of erythrocytes as revealed by phylogenetic and cell biological analysis.
Liffner, B.; Balbin, J. M.; Shami, G. J.; Strauss, J.; Frolich, S.; Heinemann, G. K.; Alder, A.; Wichers, J. S.; Tilley, L.; Dixon, M. W. A.; Gilberger, T. W.; Wilson, D. W.
10.1101/2020.11.26.400549 — microbiology — Posted on 2020-11-29
208 Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis
Teano, G.; Concia, L.; Carron, L.; Wolff, L.; Adamusova, K.; Fojtova, M.; Bourge, M.; Kramdi, A.; Colot, V.; Grossniklaus, U.; Bowler, C.; Baroux, C.; Carbonne, A.; Probst, A. V.; Prochazkova Schrumpfova, P.; Fajkus, J.; Amiard, S.; Grob, S.; Bourbousse, C.; Barneche, F.
10.1101/2020.11.28.402172 — molecular biology — Posted on 2020-11-28
210 Stool serology: development of a non-invasive immunological method for the detection of Enterovirus-specific antibodies in Congo gorilla feces
SEREME, Y.; ZARZA, S. M.; MEDKOUR, H.; Amona, I.; Fenollar, F.; Akiana, J.; Mezouar, S.; Orain, N.; Vitte, J.; Davoust, B.; Raoult, D.; Mediannikov, O.
10.1101/2020.11.28.402230 — microbiology — Posted on 2020-11-28
215 Cryptic promoter activation occurs by at least two different mechanisms in the Arabidopsis genome
Kudo, H.; Matsuo, M.; Satoh, S.; Hachisu, R.; Nakamura, M.; Yamamoto, Y. Y.; Hata, T.; Kimura, H.; Matsui, M.; Obokata, J.
10.1101/2020.11.28.399337 — evolutionary biology — Posted on 2020-11-28
219 First demonstration of the FLASH effect with ultrahigh dose-rate high energy X-rays
Gao, F.; Yang, Y.; Zhu, H.; Wang, J.; Xiao, D.; Zhou, Z.; Dai, T.; Zhang, Y.; Feng, G.; Li, J.; Lin, B.; Xie, G.; Ke, Q.; Li, P.; Sheng, X.; Wang, H.; Yan, L.; Lao, C.; Li, M.; Lu, Y.; Zhao, J.; Feng, S.; Du, X.; Wu, D.
10.1101/2020.11.27.401869 — cancer biology — Posted on 2020-11-28
221 MolDiscovery: Learning Mass Spectrometry Fragmentation of Small Molecules
Cao, L.; Guler, M.; Tagirdzhanov, A.; Lee, Y.; Gurevich, A.; Mohimani, H.
10.1101/2020.11.28.401943 — bioinformatics — Posted on 2020-11-28
225 Efficient design of maximally active and specific nucleic acid diagnostics for thousands of viruses
Metsky, H. C.; Welch, N. L.; Haradhvala, N. J.; Rumker, L.; Zhang, Y. B.; Pillai, P. P.; Yang, D. K.; Ackerman, C. M.; Weller, J.; Blainey, P. C.; Myhrvold, C.; Mitzenmacher, M.; Sabeti, P. C.
10.1101/2020.11.28.401877 — genomics — Posted on 2020-11-28
226 A highly contiguous genome assembly of a major forest pest, the Eurasian spruce bark beetle Ips typographus
Powell, D.; Grosse-Wilde, E.; Krokene, P.; Roy, A.; Chakraborty, A.; Lofstedt, C.; Vogel, H.; Andersson, M. N.; Schlyter, F. N.
10.1101/2020.11.28.401976 — genomics — Posted on 2020-11-28
227 A fish-specific new gene evolves new functions in cichlid fishes
Gu, L.; Li, C.; Mao, X.; Wei, Z.; Huang, Y.; He, X.; Zhou, W.; Li, L.; Wang, D.
10.1101/2020.11.28.391342 — evolutionary biology — Posted on 2020-11-28
228 Phenotypic plasticity, population structure and adaptation in a young weed species with a worldwide distribution
Cornille, A.; Tiret, M.; Salcedo, A.; Huang, H.; Orsucci, M.; Milesi, P.; Kryvokhyzha, D.; Holm, K.; Ge, X. J.; Stinchcombe, J. R.; Glemin, S.; Wright, S.; Lascoux, M.
10.1101/2020.11.27.401562 — evolutionary biology — Posted on 2020-11-28
231 De novo activated transcription of newborn coding sequences is inheritable in the plant genome
Hata, T.; Takada, N.; Hayakawa, C.; Kazama, M.; Uchikoba, T.; Tachikawa, M.; Matsuo, M.; Satoh, S.; Obokata, J.
10.1101/2020.11.28.402032 — evolutionary biology — Posted on 2020-11-28
233 The Coding And Small-Non-Coding Hippocampal Synaptic RNAome
Epple, R.; Krueger, D. M.; Berulava, T.; Brehm, G.; Islam, R.; Koester, S.; Fischer, A.
10.1101/2020.11.27.401901 — neuroscience — Posted on 2020-11-28
235 Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and human patients
Bayer, D.; Antonucci, S.; Mueller, H.-P.; Dupuis, L.; Boeckers, T. M.; Ludolph, A. C.; Kassubek, J.; Roselli, F.
10.1101/2020.11.28.402065 — neuroscience — Posted on 2020-11-28
238 Biomedical Graph Visualizer for Identifying Drug Candidates
Teng, A.; Villanueva, B.; Jow, D. R.; Huang, S.-C.; Piekos, S. N.; Altman, R. B.
10.1101/2020.11.27.368811 — bioinformatics — Posted on 2020-11-28
240 Molecular and electrophysiological features of spinocerebellar ataxia type seven in induced pluripotent stem cells
Burman, R. J.; Watson, L. M.; Smith, D. C.; Raimondo, J. V.; Ballo, R.; Scholefield, J.; Cowley, S. A.; Wood, M. J.; Kidson, S. H.; Greenberg, L. J.
10.1101/288480 — neuroscience — Posted on 2020-11-28
241 Transcriptomic Analysis of Early Stages of Intestinal Regeneration in Holothuria glaberrima
Quispe-Parra, D. J.; Medina-Feliciano, J. G.; Cruz-Gonzalez, S.; Ortiz-Zuazaga, H.; Garcia-Arraras, J. E.
10.1101/2020.09.23.310599 — bioinformatics — Posted on 2020-11-28
242 β-catenin signaling via astrocyte-encoded TCF7L2 regulates neuronal excitability and social behavior
Szewczyk, L. M.; Lipiec, M. A.; Liszewska, E.; Urban-Ciecko, J.; Kondrakiewicz, L.; Puscian, A.; Knapska, E.; Inoue, H.; Nowakowski, T. J.; Molofsky, A. V.; Wisniewska, M. B.
10.1101/2020.11.28.402099 — neuroscience — Posted on 2020-11-28
243 Cell segmentation-free inference of cell types from in situ transcriptomics data
Park, J.; Choi, W.; Tiesmeyer, S.; Long, B.; Borm, L. E.; Garren, E.; Nguyen, T. N.; Tasic, B.; Codeluppi, S.; Graf, T.; Schlesner, M.; Stegle, O.; Eils, R.; Ishaque, N.
10.1101/800748 — bioinformatics — Posted on 2020-11-28
245 Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite
Lin, M.-J.; Lin, Y.-C.; Chen, N.-C.; Luo, A. C.; Lai, S.-K.; Hsu, C.-L.; Hsu, J. S.; Chen, C.-Y.; Yang, W.-S.; Chen, P.-L.
10.1101/2020.11.27.399857 — genomics — Posted on 2020-11-28
247 Bradyrhizobium diazoefficiens USDA110 nodulation of Aeschynomene afraspera is associated with atypical terminal bacteroid differentiation and suboptimal symbiotic efficiency
Nicoud, Q.; Lamouche, F.; Chaumeret, A.; Balliau, T.; Le Bars, R.; Bourge, M.; Pierre, F.; Guerard, F.; Sallet, E.; Tuffigo, S.; Pierre, O.; Dessaux, Y.; Gilard, F.; Gakiere, B.; Nagy, I.; Kereszt, A.; Zivy, M.; Mergaert, P.; Gourion, B.; Alunni, B.
10.1101/2020.11.24.397182 — microbiology — Posted on 2020-11-28
249 DNA polymerase theta suppresses mitotic crossing over
Carvajal-Garcia, J.; Crown, K. N.; Ramsden, D. A.; Sekelsky, J.
10.1101/2020.11.27.400952 — genetics — Posted on 2020-11-27
251 Differential host response to a herpesvirus: Mareks disease virus peptides on chicken MHC class II molecules are derived from only a few genes and illustrate a new mode of peptide binding
Halabi, S.; Ghosh, M.; Stevanovic, S.; Rammensee, H.-G.; Bertzbach, L. D.; Kaufer, B. B.; Moncrieffe, M. C.; Kaspers, B.; Härtle, S.; Kaufman, J.
10.1101/2020.11.27.400937 — immunology — Posted on 2020-11-27
256 Characterisation and chemometric evaluation of 17 elements in ten seaweed species from Greenland
Kreissig, K. J.; Hansen, L. T.; Jensen, P. E.; Wegeberg, S.; Geertz-Hansen, O.; Sloth, J. J.
10.1101/2020.11.27.400861 — biochemistry — Posted on 2020-11-27
260 Mfd affects global transcription and the physiology of stressed Bacillus subtilis cells
Martin, H. A.; Sundararajan, A.; Ermi, T. S.; Heron, R.; Gonzales, J.; Lee, K.; Pedraza-Reyes, M.; Robleto, E. A.
10.1101/2020.11.27.401687 — microbiology — Posted on 2020-11-27
263 Comparative analysis of early divergent land plants and construction of DNA tools for hyper-expression in Marchantia chloroplasts
Frangedakis, E.; Guzman-Chavez, F.; Rebmann, M.; Markel, K.; Yu, Y.; Perraki, A.; Tse, S. W.; Liu, Y.; Rever, J.; Sauret-Gueto, S.; Goffinet, B.; Schneider, H.; Haseloff, J.
10.1101/2020.11.27.401802 — plant biology — Posted on 2020-11-27
270 Phenotypic plasticity of ER+ breast cancer in the bone microenvironment
Bado, I. L.; Wang, H.; Sarkar, P.; Liu, J.; Wu, W.; Zhang, W.; Lo, H.-C.; Muscallera, A.; Janghorban, M.; Kim, I.-S.; Singh, S.; Goldstein, A.; Singh, P.; Shixia, H.; Waleed, G. M.; Ellis, M. J.; Zhang, X. H. F.
10.1101/2020.11.14.383000 — cancer biology — Posted on 2020-11-27
271 The bone microenvironment invigorates metastatic seeds for further dissemination
Zhang, W.; Bado, I. L.; Wang, H.; Singh, S.; Lo, H.-C.; Niu, M.; Xu, Z.; Liu, J.; Jiang, W.; Li, Y.; Hu, J.; Zhang, X. H. - F.
10.1101/2020.11.16.383828 — cancer biology — Posted on 2020-11-27
273 Ablation of Proliferating Osteoblast Lineage Cells After Fracture Leads to Atrophic Nonunion in a Mouse Model
Hixon, K. R.; Sykes, D. A.; Yoneda, S.; McKenzie, J. A.; Hensley, A.; Buettmann, E. G.; Skouteris, D.; Miller, A. N.; Silva, M. J.
10.1101/2020.10.06.327288 — bioengineering — Posted on 2020-11-27
275 Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms
Guiglielmoni, N.; Houtain, A.; Derzelle, A.; van Doninck, K.; Flot, J.-F.
10.1101/2020.03.16.993428 — genomics — Posted on 2020-11-27
276 Diverse molecular mechanisms contribute to differential expression of human duplicated genes
Shew, C. J.; Carmona-Mora, P.; Soto, D. C.; Mastoras, M.; Roberts, E.; Rosas, J.; Jagannathan, D.; Kaya, G.; O'Geen, H.; Dennis, M. Y.
10.1101/2020.11.27.401752 — genomics — Posted on 2020-11-27
277 Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk
Twigger, A.-J.; Engelbrecht, L. K.; Bach, K.; Schultz-Pernice, I.; Petricca, S.; Scheel, C. H.; Khaled, W.
10.1101/2020.11.06.371443 — cell biology — Posted on 2020-11-27
278 Organization of Peptidoglycan Synthesis in Nodes and Separate Rings at Different Stages of Cell Division of Streptococcus pneumoniae
Perez, A. J.; Boersma, M. J.; Bruce, K. E.; Lamanna, M. M.; Shaw, S. L.; Tsui, H.-C. T.; Taguchi, A.; Carlson, E. E.; VanNieuwenhze, M. S.; Winkler, M. E.
10.1101/2020.09.27.315481 — microbiology — Posted on 2020-11-27
286 Decoding neural responses to motion-in-depth using EEG
Himmelberg, M. M.; Segala, F. G.; Maloney, R. T.; Harris, J. M.; Wade, A. R.
10.1101/661991 — neuroscience — Posted on 2020-11-27
287 Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist
Isaikina, P.; Tsai, C.-J.; Dietz, N. B.; Pamula, F.; Grahl, A.; Goldie, K. N.; Guixa-Gonzalez, R.; Schertler, G. F. X.; Hartley, O.; Stahlberg, H.; Maier, T.; Deupi, X.; Grzesiek, S.
10.1101/2020.11.27.401117 — biophysics — Posted on 2020-11-27
291 Rat perichondrium transplanted to articular cartilage defects forms articular-like, hyaline cartilage
Dou, Z.; Muder, D.; Baroncelli, M.; Bendre, A.; Gkourogianni, A.; Ottosson, L.; Vedung, T.; Nilsson, O.
10.1101/2020.11.27.401091 — developmental biology — Posted on 2020-11-27
292 Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection
Le Bert, N.; Clapham, H. E.; Tan, A. T.; Chia, W. N.; Tham, C. Y.; Lim, J. M.; Kunasegaran, K.; Tan, L.; Dutertre, C.-A.; Shankar, N.; Lim, J. M.; Sun, L. J.; Zahari, M.; Tun, Z. M.; Kumar, V.; Lim, B. L.; Lim, S. H.; Chia, A.; Tan, Y.-J.; Tambyah, P. A.; Kalimuddin, S.; Lye, D. C.; Low, J. G.; Wang, L.-F.; Wan, W. Y.; Hsu, L. Y.; Bertoletti, A.; Tam, C. C.
10.1101/2020.11.25.399139 — immunology — Posted on 2020-11-27
293 A Novel Cell Therapy for COVID-19 and Potential Future Pandemics: Virus Induced Lymphocytes (VIL)
Sivapalan, R.; Liu, J.; Chakraborty, K.; Arthofer, E.; Choudhry, M.; Barie, P. S.; Barouch, D. H.; Henley, T.
10.1101/2020.11.26.400390 — immunology — Posted on 2020-11-27
294 Measuring stimulus-evoked neurophysiological differentiation in distinct populations of neurons in mouse visual cortex
Mayner, W. G. P.; Marshall, W.; Billeh, Y. N.; Gandhi, S. R.; Caldejon, S.; Cho, A.; Griffin, F.; Hancock, N.; Lambert, S.; Lee, E.; Luviano, J.; Mace, K.; Nayan, C.; Nguyan, T.; North, K.; Seid, S.; Williford, A.; Cirelli, C.; Groblewski, P.; Lecoq, J.; Tononi, G.; Koch, C.; Arkhipov, A.
10.1101/2020.11.27.400457 — neuroscience — Posted on 2020-11-27
298 A mechanism for hippocampal memory recall based on excitatory-inhibitory fluctuations in neocortex
Koolschijn, R. S.; Shpektor, A.; Ip, I. B.; Clarke, W. T.; Dupret, D.; Emir, U. E.; Barron, H. C.
10.1101/2020.11.27.401299 — neuroscience — Posted on 2020-11-27
301 Human induced pluripotent stem cell-derived arteries as personalized models of atherosclerosis on-a-chip
Mallone, A.; Gericke, C.; Hosseini, V.; Vogel, V.; Chahbi, K.; Walther, J. H.; Haenseler, W.; Eckardstein, A. v.; Emmert, M. Y.; Weber, B.; Hoerstrup, S. P.
10.1101/2020.11.27.401034 — bioengineering — Posted on 2020-11-27
302 Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite
Lin, M.-J.; Lin, Y.-C.; Chen, N.-C.; Luo, A. C.-L.; Lai, S.-K.; Hsu, C.-L.; Hsu, J. S.; Chen, C.-Y.; Yang, W.-S.; Chen, P.-L.
10.1101/2020.11.27.399857 — genomics — Posted on 2020-11-27
305 CRISPR/Cas9 targeting Ttc30a mimics ciliary chondrodysplasia with polycystic kidney disease.
Getwan, M.; Hoppmann, A.; Schlosser, P.; Grand, K.; Song, W.; Diehl, R.; Schroda, S.; Heeg, F.; Deutsch, K.; Hildebrandt, F.; Lausch, E.; Koettgen, A.; Lienkamp, S. S.
10.1101/2020.11.27.400994 — developmental biology — Posted on 2020-11-27
306 3D super-resolution fluorescence microscopy maps the variable molecular architecture of the Nuclear Pore Complex
Jimenez Sabinina, V.; Hossain, M. J.; Heriche, J.-K.; Hoess, P.; Nijmeijer, B.; Mosalaganti, S.; Kueblbeck, M.; Callegari, A.; Szymborska, A.; Beck, M.; Ries, J.; Ellenberg, J.
10.1101/2020.11.27.386599 — cell biology — Posted on 2020-11-27
307 Structural basis for variable IgE reactivities of Cor a 1 hazelnut allergens
Fuehrer, S.; Kamenik, A. S.; Zeindl, R.; Nothegger, B.; Hofer, F.; Reider, N.; Liedl, K. R.; Tollinger, M.
10.1101/2020.11.27.400978 — molecular biology — Posted on 2020-11-27
308 Machine learning-based clustering of nanosized fluorescent extracellular vesicles
Kuypers, S.; Smisdom, N.; Pintelon, I.; Timmermans, J.-P.; Ameloot, M.; Michiels, L.; Hendrix, J.; Hosseinkhani, B.
10.1101/2020.11.27.374728 — molecular biology — Posted on 2020-11-27
309 Establishment of Culex modestus in Belgium and a glance into the virome of Belgian mosquito species
Wang, L.; Rosales Rosas, A. L.; De Coninck, L.; Shi, C.; Bouckaert, J.; Matthijnssens, J.; Delang, L.
10.1101/2020.11.27.401372 — microbiology — Posted on 2020-11-27
311 The Dutch Microbiome Project defines factors that shape the healthy gut microbiome
Gacesa, R.; Kurilshikov, A.; Vich Vila, A.; Sinha, T.; Klaassen, M. A. Y.; Bolte, L. A.; Andreu-Sanchez, S.; Chen, L.; Collij, V.; Hu, S.; Dekens, J. A. M.; Lenters, V. C.; Bjork, J. R.; Swarte, J. C.; Swertz, M. A.; Jansen, B. H.; Gelderloos-Arends, J.; Lifelines cohort study, ; Hofker, M.; Vermeulen, R. C. H.; Sanna, S.; Harmsen, H. J. M.; Wijmenga, C.; Fu, J.; Zhernakova, A.; Weersma, R. K.
10.1101/2020.11.27.401125 — microbiology — Posted on 2020-11-27
312 Sleeping ribosomes: bacterial signaling triggers RaiA mediated persistence to aminoglycosides.
Lang, M.; Krin, E.; Korlowski, C.; Sismeiro, O.; Varet, H.; Coppee, J.-Y.; Mazel, D.; Baharoglu, Z.
10.1101/2020.11.27.401281 — microbiology — Posted on 2020-11-27
314 A one-shot learning signal in monkey prefrontal cortex
Achterberg, J.; Kadohisa, M.; Watanabe, K.; Kusunoki, M.; Buckley, M. J.; Duncan, J.
10.1101/2020.11.27.401422 — neuroscience — Posted on 2020-11-27
318 Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy
Lövestam, S.; Schweighauser, M.; Saito, Y.; Murayama, S.; Tomita, T.; Ando, T.; Hasegawa, K.; Yoshida, M.; Tarutani, A.; Hasegawa, M.; Goedert, M.; Scheres, S.
10.1101/2020.11.27.401364 — molecular biology — Posted on 2020-11-27
320 Whole-brain dynamics of human sensorimotor adaptation
Standage, D. I.; Areshenkoff, C. N.; Gale, D. J.; Nashed, J. Y.; Flanagan, J. R.; Gallivan, J. P.
10.1101/2020.11.27.401679 — neuroscience — Posted on 2020-11-27
321 LARP6C regulates selective mRNA translation to promote pollen tube guidance in Arabidopsis thaliana.
Billey, E.; Hafidh, S.; Cruz-Gallardo, I.; Litholdo, C. G.; Jean, V.; Carpentier, M.-C.; Picart, C.; Kulichova, K.; Honys, D.; Deragon, J.-M.; Bousquet-Antonelli, C.
10.1101/2020.11.27.401307 — plant biology — Posted on 2020-11-27
327 Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits
Lim, B.; Lilascharoen, V.; Wang, E. H.-J.; Do, N.; Pate, S. C.; Tran, A. N.; Wang, X.-Y.; Park, Y.-G.; Chung, K.
10.1101/2020.11.27.401554 — neuroscience — Posted on 2020-11-27
332 Keratin-Based Epidermal Green Autofluorescence is a Common Biomarker of Organ Injury
Zhang, M.; Li, Y.; Wang, J.; Yang, Z.; Wu, D.; Tao, Y.; He, H.; Yang, Z.; Maharjan, D. T.; Tang, H.; Wang, S.; Chen, X.; Jin, L.; Ying, W.; Wang, Y.; Wei, X.; Shi, H.; Yin, S.
10.1101/564112 — biophysics — Posted on 2020-11-27
334 A spontaneous genetically-induced epiallele at a retrotransposon shapes host genome function
Bertozzi, T. M.; Hanin, G.; Takahashi, N.; Kazachenka, A.; Ferguson-Smith, A. C.
10.1101/2020.11.27.401547 — genetics — Posted on 2020-11-27
339 Identification of Gli1 as a progenitor cell marker for meniscus development and injury repair
Qin, L.; Wei, Y.; Sun, H.; Gui, T.; Yao, L.; Zhong, L.; Yu, W.; Heo, S.-J.; Han, L.; Liu, X. S.; Zhang, Y.; Koyama, E.; Long, F.; Zgonis, M. H.; Mauck, R.; Ahn, J.
10.1101/2020.11.27.401463 — developmental biology — Posted on 2020-11-27
340 Signals Secreted by Infection Induce Transcriptional and Epigenetic Changes in Neurons
McConkey, G. A.; Tedford, E.; Filippi, B. M.; Laing, C.; Badya, N. B.; Asaoka, N.; Kaneko, S.
10.1101/2020.11.26.399345 — microbiology — Posted on 2020-11-27
342 Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19
Ko, M.; Chang, S. Y.; Byun, S. Y.; Ianevski, A.; Choi, I.; d'Alexandry d'Orengiani, A. L. P. H.; Kainov, D.; Shum, D.; Min, J.-Y.; Windisch, M. P.
10.1101/2020.02.25.965582 — microbiology — Posted on 2020-11-27
346 Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes
Druart, M.; Nosten-Bertrand, M.; Poll, S.; Crux, S.; Nebeling, F.; Delhaye, C.; Dubois, Y.; Leboyer, M.; Tamouza, R.; Fuhrmann, M.; Le Magueresse, C.
10.1101/2020.11.27.400960 — neuroscience — Posted on 2020-11-27
347 Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior
Soares-Cunha, C.; Correia, R.; Domingues, A. V.; Coimbra, B.; de Vasconcelos, N. A.; Pinto, L.; Sousa, N.; Rodrigues, A. J.
10.1101/2020.11.27.401042 — neuroscience — Posted on 2020-11-27
350 Validation of a novel associative transcriptomics pipeline in Brassica oleracea: Identifying candidates for vernalisation response
Woodhouse, S. M.; He, Z.; Woolfenden, H.; Steuernagel, B.; Haerty, W. `; Bancroft, I.; Irwin, J. `; Morris, R. J.; Wells, R.
10.1101/2020.11.27.400986 — plant biology — Posted on 2020-11-27
351 Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge
Yamashita, D.; Botta, D.; Cho, H. J.; Guo, X.; Ozaki, S.; Flanary, V. L.; Sirota, I.; Gao, M.; Yamaguchi, S.; Nakano, M. A.; Zhou, F.; Zhou, H.; Kondo, T.; Kunieda, T.; Crossman, D.; Kornblum, H.; Gorospe, M.; Nam, D.-H.; Zamboni, N.; Gu, Z.; Lund, F. E.; Nakano, I.
10.1101/2020.11.26.399725 — cancer biology — Posted on 2020-11-27
354 Fast and sensitive taxonomic assignment to metagenomic contigs
Mirdita, M.; Steinegger, M.; Breitwieser, F.; Soeding, J.; Levy Karin, E.
10.1101/2020.11.27.401018 — bioinformatics — Posted on 2020-11-27
357 New Structural Insights into the Function of the Catalytically Active Human Taspase1
Nagaratnam, N.; Delker, S.; Jernigan, R.; Edwards, T. E.; Snider, J.; Thifault, D.; Williams, D.; Nannenga, B. L.; Stofega, M.; Sambucetti, L.; Hsieh, J.; Flint, A. J.; Fromme, P.; Martin-Garcia, J. M.
10.1101/2020.11.26.400622 — biochemistry — Posted on 2020-11-27
360 Trends of genetic changes uncovered by Env- and Eigen-GWAS in wheat and barley
Sharma, R.; Cockram, J.; Gardner, K. A.; Russell, J.; Ramsay, L.; Thomas, W. T.; O'Sullivan, D. M.; Powell, W.; Mackay, I. J.
10.1101/2020.11.27.400333 — genetics — Posted on 2020-11-27
361 Heritability of DNA methylation in threespine stickleback (Gasterosteus aculeatus)
Hu, J.; Wuitchik, S. J. S.; Barry, T. N.; Rogers, S. M.; Jamniczky, H. A.; Barrett, R. D. H.
10.1101/2020.11.26.400531 — evolutionary biology — Posted on 2020-11-27
362 Resistance to platinum chemotherapy in lung adenocarcinoma is driven by a non-genetic, cell-cycle dependent mechanism
Gonzalez-Rajal, A.; McCloy, R. A.; Nobis, M.; Marzec, K.; Chin, V.; Hastings, J. F.; Lai, K.; Kennerson, M.; Vaghjiani, V.; Hughes, W. E.; Timpson, P.; Cain, J.; Watkins, D. N.; Croucher, D. R.; Burgess, A.
10.1101/2020.11.26.400499 — cell biology — Posted on 2020-11-27
363 Pfcerli2, a duplicated gene in the malaria parasite Plasmodium falciparum essential for invasion of erythrocytes as revealed by phylogenetic and cell biological analysis.
Liffner, B.; Balbin, J. M.; Shami, G. J.; Strauss, J.; Frolich, S.; Heinemann, G. K.; Alder, A.; Wichers, J. S.; Tilley, L.; Dixon, M. W. A.; Gilberger, T. W.; Wilson, D. W.
10.1101/2020.11.26.400549 — microbiology — Posted on 2020-11-27
366 CA2 inhibition reduces the precision of hippocampal assembly reactivation
He, H.; Boehringer, R.; Huang, A. J. Y.; Overton, E. T. N.; Polygalov, D.; Okanoya, K.; McHugh, T. J.
10.1101/2020.11.26.400655 — neuroscience — Posted on 2020-11-27
367 Patient-derived models of brain metastases recapitulate the histopathology and biology of human metastatic cancers
Faria, C. C.; Custodia, C.; Cascao, R.; Paisana, E.; Carvalho, T.; Pereira, P.; Roque, R.; Pimentel, J.; Miguens, J.; Barata, J. T.
10.1101/2020.11.26.400036 — cancer biology — Posted on 2020-11-27
370 Predicting the impact of sequence motifs on gene regulation using single-cell data
Hepkema, J.; Lee, N. K.; Stewart, B. J.; Ruangroengkulrith, S.; Charoensawan, V.; Clatworthy, M. R.; Hemberg, M.
10.1101/2020.11.26.400218 — bioinformatics — Posted on 2020-11-27
371 FrustratometeR: an R-package to compute Local frustration in protein structures, point mutants and MD simulations
Rausch, A. O.; Freiberger, M. I.; Leonetti, C. O.; Luna, D. M.; Radusky, L. G.; Wolynes, P. G.; Ferreiro, D. U.; Parra, R. G.
10.1101/2020.11.26.400432 — bioinformatics — Posted on 2020-11-27
373 A novel high-accuracy genome assembly method utilizing a high-throughput workflow
Zeng, Q.; Cao, W.; Xing, L.; Qin, G.; Wu, J.; Nagle, M. F.; Xiong, Q.; Chen, J.; Yang, L.; Bajaj, P.; Chitikineni, A.; Zhou, Y.; Yu, Y.; Xu, J.; Nie, X.; Huang, L.; Liu, S.; Safar, J.; Simkova, H.; Song, W.; Guo, B.; Chen, S.; Dolezel, J.; Hao, Z.; Cheng, Q.; Liang, J.; Tang, J.; Cao, A.; Wang, Q.; Lu, X.; Yang, S.; Ma, H.; Liu, J.; Wang, X.; Zhang, H.; Wang, Z.; Ji, W.; Wang, C.; Yuan, F.; Shi, J.; Varshney, R. K.; Kang, Z.; Han, D.; Xu, H.
10.1101/2020.11.26.400507 — genomics — Posted on 2020-11-27
374 Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction
Albinana, C.; Grove, J.; McGrath, J. J.; Agerbo, E.; Wray, N. R.; Werge, T.; Borglum, A. D.; Mortensen, P. B.; Prive, F.; Vilhjalmsson, B. J.
10.1101/2020.11.27.401141 — genetics — Posted on 2020-11-27
380 Loss of choline agonism in the inner ear hair cell nicotinic acetylcholine receptor linked to the α10 subunit
Moglie, M. J.; Marcovich, I.; Corradi, J.; Carpaneto Freixas, A. E.; Gallino, S.; Plazas, P. V.; Bouzat, C.; Lipovsek, M.; Elgoyhen, A. B.
10.1101/2020.11.26.400291 — neuroscience — Posted on 2020-11-27
381 Naturalistic affective behaviors decoded from spectro-spatial features of multi-day human intracranial recordings
Bijanzadeh, M.; Khambhati, A. N.; Desai, M.; Wallace, D. L.; Shafi, A.; Dawes, H. E.; Sturm, V. E.; Chang, E. F.
10.1101/2020.11.26.400374 — neuroscience — Posted on 2020-11-27
390 Robotic Search for Optimal Cell Culture in Regenerative Medicine
Kanda, G. N.; Tsuzuki, T.; Terada, M.; Sakai, N.; Motozawa, N.; Masuda, T.; Nishida, M.; Watanabe, C. T.; Higashi, T.; Horiguchi, S. A.; Kudo, T.; Kamei, M.; Sunagawa, G. A.; Matsukuma, K.; Sakurada, T.; Ozawa, Y.; Takahashi, M.; Takahashi, K.; Natsume, T.
10.1101/2020.11.25.392936 — systems biology — Posted on 2020-11-27
392 Genetics of nodulation in Aeschynomene evenia uncovers new mechanisms of the rhizobium-legume symbiosis
Quilbe, J.; Lamy, L.; Brottier, L.; Leleux, P.; Fardoux, J.; Rivallan, R.; Benichou, T.; Guyonnet, R.; Becana, M.; Villar, I.; Garsmeur, O.; Hufnagel, B.; Delteil, A.; Gully, D.; Chaintreuil, C.; Pervent, M.; Cartieaux, F.; Bourge, M.; Valentin, N.; Martin, G.; Fontaine, L.; Droc, G.; Dereeper, A.; Farmer, A.; Libourel, C.; Nouwen, N.; Gressent, F.; Mournet, P.; d'Hont, A.; Giraud, E.; Klopp, C.; ARRIGHI, J.-F.
10.1101/2020.11.26.399428 — plant biology — Posted on 2020-11-27
394 High throughput functional screening for next generation cancer immunotherapy using droplet-based microfluidics
Wang, Y.; Jin, R.; Shen, B.; Li, N.; Zhou, H.; Wang, W.; Zhao, Y.; Huang, M.; Fang, P.; Wang, S.; Mary, P.; Wang, R.; Ma, P.; Li, R.; Cao, Y.; Li, F.; Schweizer, L.; Zhang, h.
10.1101/2020.11.25.399188 — cancer biology — Posted on 2020-11-27
400 The choice of plant provenance for ecological restoration affects pollinator network
Bucharova, A.; Lampei, C.; Conrady, M.; May, E.; Matheja, J.; Meyer, M.; Ott, D.
10.1101/2020.11.26.399493 — ecology — Posted on 2020-11-27
401 DNA metabarcoding successfully quantifies relative abundances of arthropod taxa in songbird diets: a validation study using camera-recorded diets
Verkuil, Y. I.; Nicolaus, M.; Ubels, R.; Dietz, M. M.; Samplonius, J. M.; Galema, A.; Kiekebos, K.; de Knijff, P.; Both, C.
10.1101/2020.11.26.399535 — ecology — Posted on 2020-11-27
404 High mannose N-glycans on red blood cells as phagocytic ligands, mediating both sickle cell anaemia and resistance to malaria
Cao, H.; Antonopoulos, A.; Henderson, S.; Wassall, H.; Brewin, J.; Masson, A.; Shepard, J.; Konieczny, G.; Patel, B.; Williams, M.-L.; Davie, A. I.; Forrester, M.; Hall, L.; Minter, B.; Tampakis, D.; Moss, M.; Lennon, C.; Pickford, W.; Erwig, L.; Robertson, B.; Dell, A.; Brown, G.; Wilson, H.; Rees, D.; Haslam, S.; Rowe, A. J.; Barker, R. N.; Vickers, M. A.
10.1101/2020.11.26.399402 — immunology — Posted on 2020-11-27
406 Hybrid Hyperalignment: A single high-dimensional model of shared information embedded in cortical patterns of response and functional connectivity
Busch, E. L.; Slipski, L.; Feilong, M.; Guntupalli, J. S.; Visconti di Oleggio Castello, M.; Huckins, J. F.; Nastase, S. A.; Gobbini, M. I.; Wager, T. D.; Haxby, J. V.
10.1101/2020.11.25.398883 — neuroscience — Posted on 2020-11-27
407 Muscle Van Gogh-like 2 shapes the neuromuscular synapse by regulating MuSK signaling activity
Boex, M.; Messeant, J.; Cottin, S.; Halliez, M.; Bauche, S.; Buon, C.; Sans, N.; montcouquiol, m.; Molgo, J.; Amar, M.; Ferry, A.; Lemaitre, M.; Rouche, A.; Langui, D.; Baskaran, A.; Fontaine, B.; Strochlic, L.
10.1101/2020.11.26.384925 — neuroscience — Posted on 2020-11-27
409 Cyber-yeast: Automatic synchronisation of the cell cycle in budding yeast through closed-loop feedback control
Perrino, G.; Napolitano, S.; Galdi, F.; La Regina, A.; Fiore, D.; Giuliano, T.; di Bernardo, M.; di Bernardo, D.
10.1101/2020.11.25.398768 — synthetic biology — Posted on 2020-11-27
411 Arabidopsis bZIP11 is a susceptibility factor during Pseudomonas syringae infection
Prior, M. J.; Selvanayagam, J.; Kim, J.-G.; Tomar, M.; Jonikas, M. C.; Mudgett, M. B.; Smeekens, S.; Hanson, J.; Frommer, W. B.
10.1101/2020.11.25.398727 — plant biology — Posted on 2020-11-27
412 Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia
Heltemes-Harris, L. M.; Hubbard, G.; LaRue, R. S.; Munro, S. A.; Knutson, T. P.; Yang, R.; Henzler, C. M.; Starr, T. K.; Sarver, A. L.; Kornblau, s. M.; Farrar, M. A.
10.1101/2020.11.25.398966 — cancer biology — Posted on 2020-11-27
413 3D Adaptive Optical Nanoscopy for Thick Specimen Imaging at sub-50 nm Resolution
Hao, X.; Allgeyer, E. S.; Antonello, J.; Watters, K.; Gerdes, J. A.; Schroeder, L. K.; Bottanelli, F.; Zhao, J.; Kidd, P.; Lessard, M. D.; Rothman, J. E.; Cooley, L.; Biederer, T.; Booth, M. J.; Bewersdorf, J.
10.1101/2020.11.25.398958 — biophysics — Posted on 2020-11-27
419 Eosinophil peroxidase induces inflammation in an animal model of dermatitis
Roth-Carter, Q.; Luo, H.; Ochkur, S. I.; Jacobsen, E.; Datena, M.; Fryer, A. D.; Lee, J. J.; Jacoby, D. B.
10.1101/2020.11.25.399006 — immunology — Posted on 2020-11-27
421 Electrophysiological signatures of acute systemic lipopolysaccharide: potential implications for delirium science
Sultan, Z. W.; Jaeckel, E. R.; Krause, B. M.; Grady, S. M.; Murphy, C. A.; Sanders, R. D.; Banks, M. I.
10.1101/2020.11.25.398388 — neuroscience — Posted on 2020-11-27
424 Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting its Protein-Protein Interactions
Bobone, S.; Pannone, L.; Biondi, B.; Solman, M.; Flex, E.; Canale, V.; Calligari, P.; De Faveri, C.; Gandini, T.; Quercioli, A.; Torini, G.; Venditti, M.; Lauri, A.; Fasano, G.; Hoeksma, J.; Santucci, V.; Cattani, G.; Bocedi, A.; Carpentieri, G.; Tirelli, V.; Sanchez, M.; Peggion, C.; Formaggio, F.; Den Hertog, J.; Martinelli, S.; Bocchinfuso, G.; Tartaglia, M.; Stella, L.
10.1101/2020.08.28.271809 — biophysics — Posted on 2020-11-27
425 Transcriptional regulation of structural and functional adaptations in a developing adulthood myocardium
Sunny, S.; Challa, A. K.; Barchue, J. P.; Ramamurthy, M. T.; Crossman, D. K.; Pogwizd, S.; Cinghu, S.; Namakkal-Soorappan, R.
10.1101/2020.11.25.397885 — genomics — Posted on 2020-11-27
426 Physiological role of the 3'IgH CBEs super-anchor in antibody class switching
Zhang, X.; Yoon, H.; Chapdelaine-Williams, A. M.; Kyritsis, N.; Alt, F. W.
10.1101/2020.11.25.398404 — immunology — Posted on 2020-11-27
427 Serum Metabolites Associate with Brain Amyloid Beta Deposition, Cognitive Dysfunction, and Alzheimers Disease Progression
Nho, K.; Kueider-Paisley, A.; Arnold, M.; MahmoudianDehkordi, S.; Risacher, S. L.; Louie, G.; Blach, C.; Baillie, R.; Han, X.; Kastenmüller, G.; Doraiswamy, P. M.; Kaddurah-Daouk, R.; Saykin, A. J.; Alzheimer's Disease Neuroimaging Initiative, ; Alzheimer's Disease Metabolomics Consortium,
10.1101/2020.11.25.394262 — neuroscience — Posted on 2020-11-27
429 Establishment of Multi-stage Models of Drug Taking and Seeking in Mice
Slosky, L. M.; Pires, A.; Bai, Y.; Clark, N.; Hauser, E. R.; Gross, J. D.; Porkka, F.; Pogorelov, V. M.; Toth, K.; Wetsel, W. C.; Barak, L. S.; Caron, M. G.
10.1101/2020.11.25.398503 — neuroscience — Posted on 2020-11-27
434 Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2
Ferreira de Freitas, R.; Liu, Y.; Szewczyk, M.; Mehta, N.; Li, F.; McLeod, D.; Zepeda-Velazquez, C.; Dilworth, D.; Hanley, R. P.; Gibson, E.; Brown, P. J.; Al-Awar, R.; Ingerman James, L.; Arrowsmith, C. H.; Barsyte-Lovejoy, D.; Min, J.; Vedadi, M.; Schapira, M.; Allali-Hassani, A.
10.1101/2020.11.25.398586 — pharmacology and toxicology — Posted on 2020-11-27
436 The complex history of genome duplication andhybridization in North American gray treefrogs
Booker, W. W.; Gerhardt, H. C.; Lemmon, A. R.; Ptacek, M.; Hassinger, A. T.; Schul, J.; Lemmon, E. M.
10.1101/2020.11.25.398461 — genomics — Posted on 2020-11-27
438 A developmentally programmed splicing failure attenuates the DNA damage response during mammalian zygotic genome activation
Wyatt, C. D. R.; Pernaute, B.; Gohr, A.; Miret-Cuesta, M.; Goyeneche, L.; Rovira, Q.; Bogdanovic, O.; Bonnal, S.; Irimia, M.
10.1101/2020.11.25.397794 — developmental biology — Posted on 2020-11-27
439 The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency
Takahashi, K.; Nakamura, M.; Narita, M.; Watanabe, A.; Ueda, M.; Takashima, Y.; Yamanaka, S.
10.1101/2020.11.25.397935 — cell biology — Posted on 2020-11-27
440 Non-invasive surveys of mammalian viruses using environmental DNA
Alfano, N.; Dayaram, A.; Axtner, J.; Tsangaras, K.; Kampmann, M.-L.; Mohamed, A.; Wong, S. T.; Gilbert, M. T. P.; Wilting, A.; Greenwood, A. D.
10.1101/2020.03.26.009993 — molecular biology — Posted on 2020-11-27
441 A systematic evaluation of IgM and IgG antibody assay accuracy in diagnosing acute Zika Virus infection in Brazil; lessons relevant to emerging infections
Medialdea-Carrera, R.; Lowen Levy Chalhoub, F.; Castanha, P.; Carvalho Sequeira, P.; Brasil, P.; Lewis Ximenez, L. L.; Turtle, L.; Solomon, T.; Bispo de Filippis, A. M.; Brown, D. W.; Griffiths, M.
10.1101/2020.11.25.399386 — microbiology — Posted on 2020-11-27
442 SCENITH: A flow cytometry based method to functionally profile energy metabolism with single cell resolution
ARGUELLO, R. J.; COMBES, A. J.; CHAR, R.; BOUSIQUOT, E.; GIGAN, J. P.; CAMOSSETO, V.; SAMAD, B.; TSUI, J.; YAN, P.; BOISSONNEAU, S.; FIGARELLA-BRANGER, D.; GATTI, E.; TABOURET, E.; Krummel, M. F.; PIERRE, P.
10.1101/2020.03.10.985796 — immunology — Posted on 2020-11-27
443 Microstructural underpinnings and macroscale functional implications of temporal lobe connectivity gradients
Vos de Wael, R.; Royer, J.; Tavakol, S.; Wang, Y.; Paquola, C.; Benkarim, O.; Eichert, N.; Lariviere, S.; Misic, B.; Smallwood, J.; Valk, S.; Bernhardt, B.
10.1101/2020.11.26.400382 — neuroscience — Posted on 2020-11-27
444 Enhanced virus detection and metagenomic sequencing in patients with meningitis and encephalitis
Piantadosi, A.; Mukerji, S. S.; Ye, S.; Leone, M. J.; Freimark, L.; Park, D. J.; Adams, G.; Lemieux, J.; Kanjilal, S.; Solomon, I. H.; Ahmed, A. A.; Goldstein, R.; Ganesh, V.; Ostrem, B.; Cummins, K. C.; Thon, J.; Kinsella, C. M.; Rosenberg, E. S.; Frosh, M. P.; Goldberg, M. B.; Cho, T.; Sabeti, P.
10.1101/2020.11.25.399394 — neuroscience — Posted on 2020-11-27
452 Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation
Shi, Y.; Wang, X.; Liu, L.; Whisnant, A.; Hennig, T.; Djakovic, L.; Haque, N.; Bach, C.; Sandri-Goldin, R.; Erhard, F.; Friedel, C.; Dölken, L.
10.1101/2020.11.26.399626 — molecular biology — Posted on 2020-11-26
454 Multimodal imaging evidence for the brain basis of cognitive dysfunction in older HIV+ men
Fernandez Cruz, A. L.; Chen, C.-M.; Sanford, R.; Collins, D. L.; Brouillette, M.-J.; Mayo, N. E.; Fellows, L.
10.1101/2020.11.26.399592 — neuroscience — Posted on 2020-11-26
455 CHD8 haploinsufficiency alters the developmental trajectories of human excitatory and inhibitory neurons linking autism phenotypes with transient cellular defects
Villa, C. E.; Cheroni, C.; Lopez-Tobon, A.; Dotter, C.; Oliveira, B.; Sacco, R.; Yahya, A. C.; Morandell, J.; Gabriele, M.; Sommer, C.; Gabitto, M.; Testa, G.; Novarino, G.
10.1101/2020.11.26.399469 — neuroscience — Posted on 2020-11-26
456 Hippocampal Egr1-dependent neuronal ensemblesnegatively regulate motor learning
GIRALT, A.; Brito, V.; Montalban, E.; Pupak, A.; Masana, M.; Gines, S.; Alberch, J.; Martin, C.; Girault, J.-A.
10.1101/2020.11.26.399949 — neuroscience — Posted on 2020-11-26
457 A selective projection from the subthalamic nucleus to parvalbumin-expressing interneurons of the striatum
Kondabolu, K.; Doig, N. M.; Ayeko, O.; Kahn, B.; Torres, A.; Calvigioni, D.; Meletis, K.; Magill, P. J.; Koos, T.
10.1101/2020.11.26.400242 — neuroscience — Posted on 2020-11-26
458 The cerebellum is involved in internal and external speech error monitoring
Runnqvist, E.; Chanoine, V.; Strijkers, K.; Pattamadilok, C.; Bonnard, M.; Nazarian, B.; Sein, J.; Anton, J.-L.; Belin, P.; Alario, F.- X.
10.1101/2020.11.26.400317 — neuroscience — Posted on 2020-11-26
464 Direct Observation of the Mechanism of Antibiotic Resistance by Mix-and-Inject at the European XFEL
Pandey, S.; Calvey, G.; Katz, A. M.; Malla, T. N.; Koua, F.; Martin-Garcia, J.; Poudyal, I.; Yang, J.-H.; Vakili, M.; Yefanov, O.; Zielinski, K. A.; Bajt, S.; Awel, S.; Doerner, K.; Frank, M.; Gelisio, L.; Jernigan, R.; Kirkwood, H.; Kloos, M.; Koliyadu, J.; Mariani, V.; Miller, M. D.; Mills, G.; Nelson, G.; Olmos, J. L.; Sadri, A.; Sato, T.; Tolstikova, A.; Xu, W.; Ourmazd, A.; Spence, J. H. C.; Schwander, P.; Barty, A.; Chapman, H.; Fromme, P.; Mancuso, A.; Phillips, G.; Bean, R.; Pollack, L.; Schmidt, M.
10.1101/2020.11.24.396689 — biophysics — Posted on 2020-11-26
469 Host specialization in microparasites transmitted by generalist vectors: insights into the cellular and immunological mechanisms
Lin, Y.-P.; Tufts, D. M.; Dupuis, A. P.; Combs, M.; Marcinkiewicz, A. L.; Hirsbrunner, A. D.; Diaz, A. J.; Stout, J. L.; Blom, A. M.; Strle, K.; Davis, A. D.; Kramer, L. D.; Diuk-Wasser, M. A.
10.1101/2020.11.13.380550 — microbiology — Posted on 2020-11-26
471 CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
Hosokawa, T.; Liu, P.-W.; Cai, Q.; Ferreira, J. S.; Levet, F.; Butler, C.; Sibarita, J.-B.; Choquet, D.; Groc, L.; Hosy, E.; Zhang, M.; Hayashi, Y.
10.1101/2020.11.25.397091 — neuroscience — Posted on 2020-11-26
473 Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET
Maslov, I.; Volkov, O.; Khorn, P.; Orekhov, P.; Gusach, A.; Kuzmichev, P.; Gerasimov, A.; Luginina, A.; Coucke, Q.; Bogorodskiy, A.; Gordeliy, V.; Wanninger, S.; Barth, A.; Hofkens, J.; Cherezov, V.; Gensch, T.; Hendrix, J.; Borshchevskiy, V.
10.1101/2020.11.26.400184 — biophysics — Posted on 2020-11-26
474 NAP-CNB: Bioinformatic pipeline to predict MHC-I-restricted T cell epitopes in mice
Wert-Carvajal, C.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Mendez Perez, A.; Alemany, R.; Veiga, E.; Sorzano, C. O. S.; Munoz-Barrutia, A.
10.1101/2020.10.05.327015 — bioinformatics — Posted on 2020-11-26
477 Genomic adaptations to an endolithic lifestyle in the coral-associated alga Ostreobium
Iha, C.; Dougan, K. E.; Varela, J. A.; Avila, V.; Jackson, C. J.; Bogaert, K. A.; Chen, Y.; Judd, L. M.; Wick, R. R.; Holt, K. E.; Pasella, M. M.; Ricci, F.; Repetti, S. I.; Medina, M.; Marcelino, V. R.; Chan, C. X.; Verbruggen, H.
10.1101/2020.07.21.211367 — genomics — Posted on 2020-11-26
479 Centromere drive and suppression by parallel pathways for recruiting microtubule destabilizers
Kumon, T.; Ma, J.; Stefanik, D.; Nordgren, E. C.; Akins, R. B.; Kim, J.; Levine, M. T.; Lampson, M.
10.1101/2020.11.26.400515 — evolutionary biology — Posted on 2020-11-26
481 A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner
Sanz-Castillo, B.; Hurtado, B.; El Bakkali, A.; Hermida, D.; Salvador-Barbero, B.; Martinez-Alonso, D.; Gonzalez-Martinez, J.; Santiveri, C.; Campos-Oliva, R.; Ximenez, P.; Munoz, J.; Alvarez-Fernandez, M.; Malumbres, M.
10.1101/2020.11.26.399915 — cell biology — Posted on 2020-11-26
483 Gut microbiome composition predicts summer core range size in a generalist and specialist ungulate
Wolf, J. F.; Kriss, K. D.; MacAulay, K. M.; Munro, K.; Patterson, B. R.; Shafer, A. B. A.
10.1101/2020.08.04.236638 — molecular biology — Posted on 2020-11-26
485 An Optimised GAS-pharyngeal cell biofilm model
Vyas, H. K. N.; McArthur, J. D.; Sanderson-Smith, M. L.
10.1101/2020.11.25.399196 — microbiology — Posted on 2020-11-26
489 Combined inhibition of KDM6A/B and HDACs exacerbates integrated stress response and mediates therapeutic effects in IDH1-mutant glioma
Kayabolen, A.; Sahin, G. N.; Seker-Polat, F.; Cingoz, A.; Isik, B.; Acar, S.; Wakimoto, H.; Cahill, D. P.; Solaroglu, I.; Cribbs, A.; Oppermann, U.; Bagci-Onder, T.
10.1101/2020.11.26.400234 — cancer biology — Posted on 2020-11-26
490 Tumor irradiation combined with vascular-targeted photodynamic therapy enhances anti-tumor effects in preclinical prostate cancer.
Sjoberg, H. T.; Philippou, Y. J.; Magnussen, A. L.; Tullis, I. D.; Bridges, E.; Chatrian, A.; Loefebvre, J.; Tam, K. H.; Murphy, E. A.; Rittscher, J.; Preise, D.; Agemy, L.; Yechezkel, T.; Smart, S. C.; Kinchesh, P.; Gilchrist, S.; Allen, D. P.; Scheiblin, D. A.; Lockett, S. J.; Wink, D. A.; Lamb, A. D.; Mills, I. G.; Harris, A.; Muschel, R. J.; Vojnovic, B.; Scherz, A.; Hamdy, F. C.; Bryant, R. J.
10.1101/2020.11.26.400283 — cancer biology — Posted on 2020-11-26
493 An unexpected donor in the adaptive introgression candidate Helianthus annuus subsp. texanus.
Owens, G. L.; Todesco, M.; Bercovich, N.; Legare, J.-S.; Mitchell, N.; Whitney, K. D.; Rieseberg, L. H.
10.1101/2020.11.26.398933 — evolutionary biology — Posted on 2020-11-26
495 Archaeogenomics of a ~2,100-year-old Egyptian leaf provides a new timestamp on date palm domestication
Perez-Escobar, O. A.; Bellot, S.; Gros-Balthazard, M.; Flowers, J. M.; Nesbitt, M.; Ryan, P.; Gutaker, R. M.; Wells, T.; Schley, R. J.; Bogarin, D.; Przelomska, N.; Dodsworth, S.; Diaz, R.; Lehmann, M.; Petoe, P.; Eiserhardt, W.; Preick, M.; Hofreiter, M.; Hajdas, I.; Antonelli, A.; Leitch, I. J.; Gravendeel, B.; Torres, M. F.; Chomicki, G.; Renner, S. S.; PAPADOPULOS, A.; Purugganan, M.; Baker, W.
10.1101/2020.11.26.400408 — evolutionary biology — Posted on 2020-11-26
496 Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies.
Lake, A. V. R.; Smith, C. E. L.; Natarajan, S.; Basu, B.; Best, S. K.; Stevenson, T.; Trowbridge, R.; Grellscheid, S. N.; Bond, J.; Foster, R.; Johnson, C. A.
10.1101/2020.11.26.393801 — cell biology — Posted on 2020-11-26
499 Identification of fungal limonene-3-hydroxylases for biotechnological menthol production
Schempp, F. M.; Strobel, I.; Etschmann, M. M. W.; Bierwirth, E.; Panten, J.; Schewe, H.; Schrader, J.; Buchhaupt, M.
10.1101/2020.11.25.399378 — microbiology — Posted on 2020-11-26
501 Type VI secretion system killing by commensal Neisseria is influenced by the spatial dynamics of bacteria
Custodio, R.; Ford, R. M.; Ellison, C. J.; Liu, G.; Mickute, G.; Tang, C. M.; Exley, R. M.
10.1101/2020.11.26.400259 — microbiology — Posted on 2020-11-26
503 Digestion, fermentation, and pathogen anti-adhesive properties of the hMO-mimic di-fucosyl-β-cyclodextrin
Verkhnyatskaya, S. A.; Kong, C.; Klostermann, C.; Schols, H. A.; de Vos, P.; Walvoort, M. T. C.
10.1101/2020.11.26.399972 — microbiology — Posted on 2020-11-26
504 The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells
Finetti, F.; Cassioli, C.; Cianfanelli, V.; Zevolini, F.; Onnis, A.; Gesualdo, M.; Brunetti, J.; Cecconi, F.; Baldari, C. T.
10.1101/2020.11.26.400135 — immunology — Posted on 2020-11-26
505 Phasic inhibition of dopamine neurons is an instrumental punisher
Peng, C. Y.; Jean Richard dit Bressel, P.; Gilchrist, S.; Power, J. M.; McNally, G.
10.1101/2020.11.25.399220 — neuroscience — Posted on 2020-11-26
507 Structural and biochemical analysis of OrfG: the VirB8-like component of the integrative and conjugative element ICESt3 from Streptococcus thermophilus
Cappele, J.; Mohamad-Ali, A.; Leblond-Bourget, N.; Mathiot, S.; Dhalleine, T.; Payot, S.; Savko, M.; Didierjean, C.; Favier, F.; Douzi, B.
10.1101/2020.11.26.395491 — biochemistry — Posted on 2020-11-26
508 Free-fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
Croze, M. L.; Flisher, M.; Guillaume, A.; Tremblay, C.; Noguchi, G. M.; Granziera, S.; Vivot, K.; Castillo, V. C.; Campbell, S. A.; Ghislain, J.; Huising, M. O.; Poitout, V.
10.1101/2020.07.17.208637 — physiology — Posted on 2020-11-26
510 The development of attentional control mechanisms in multisensory environments
Turoman, N.; Tivadar, R. I.; Retsa, C.; Maillard, A. M.; Scerif, G.; Matusz, P. J.
10.1101/2020.06.23.166975 — neuroscience — Posted on 2020-11-26
511 Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro
Raymonda, M. H.; Ciesla, J. H.; Monaghan, M.; Leach, J.; Asantewaa, G.; Smorodintsev-Schiller, L. A.; Lutz, M. M.; Schafer, X. L.; Takimoto, T.; Dewhurst, S.; Munger, J.; Harris, I. S.
10.1101/2020.11.25.398859 — microbiology — Posted on 2020-11-26
512 Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods
Ginez, T.; Garaigorta, U.; Ramirez, D.; Castro, V.; Nozal, V.; Maestro, I.; Garcia-Carceles, J.; Campillo, N. E.; Martinez, A.; Gastaminza, P.; Gil, C.
10.1101/2020.11.26.399436 — microbiology — Posted on 2020-11-26
518 Accelerating Drug Discovery and Repurposingby Combining Transcriptional Signature Connectivity with Docking
Thorman, A. W.; Reigle, J.; Chutipongtanate, S.; Shamsaei, B.; Pilarczyk, M.; Fazel-Najafabadi, M.; Adamczak, R.; Kouril, M.; Morrow, A. L.; Czyzyk-Krzeska, M. F.; McCullumsmith, R.; Seibel, W.; Nassar, N.; Zheng, Y.; Hildeman, D.; Herr, A. B.; Medvedovic, M.; Meller, J.
10.1101/2020.11.25.399238 — bioinformatics — Posted on 2020-11-26
519 How ancient forest fragmentation and riparian connectivity generate high levels of genetic diversity in a micro-endemic Malagasy tree
Salmona, J.; Dresen, A.; Ranaivoson, A. E.; Manzi, S.; Le Pors, B.; Hong-Wa, C.; Razanatsoa, J.; Andriaholinirina, N. V.; Rasoloharijaona, S.; Vavitsara, M.-E.; Besnard, G.
10.1101/2020.11.25.394544 — genomics — Posted on 2020-11-26
522 A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Carhart-Harris, R. L.; Williams, G. B.; Craig, M. M.; Finoia, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2020.11.25.398081 — neuroscience — Posted on 2020-11-26
524 Cutting through the noise: reducing bias in motor adaptation analysis
Blustein, D.; Shehata, A.; Kuylenstierna, E.; Englehart, K.; Sensinger, J.
10.1101/2020.11.25.397992 — neuroscience — Posted on 2020-11-26
530 The mutational landscape of human somatic and germline cells
Moore, L.; Cagan, A.; Coorens, T.; Neville, M. D. C.; Sanghvi, R.; Sanders, M. A.; Oliver, T. R. W.; Leongamornlert, D.; Ellis, P.; Noorani, A.; Mitchell, T. J.; Butler, T. M.; Hooks, Y.; Warren, A. Y.; Jorgensen, M.; Dawson, K. J.; Menzies, A.; ONeill, L.; Latimer, C.; Teng, M.; VanBoxtel, R.; Iacobuzio-Donahue, C. A.; Martincorena, I.; Heer, R.; Campbell, P.; Fitzgerald, R. C.; Stratton, M.; Rahbari, R.
10.1101/2020.11.25.398172 — genomics — Posted on 2020-11-26
533 Automatic identification of bird females using egg phenotype
Sulc, M.; Hughes, A. E.; Troscianko, J.; Stetkova, G.; Prochazka, P.; Pozgayova, M.; Pialek, L.; Pialkova, R.; Brlik, V.; Honza, M.
10.1101/2020.11.25.398131 — ecology — Posted on 2020-11-26
534 QSM Reconstruction Challenge 2.0: Design and Report of Results
QSM Challenge 2.0 Organization Committee, ; Bilgic, B.; Langkammer, C.; Marques, J. P.; Meineke, J.; Milovic, C.; Schweser, F.
10.1101/2020.11.25.397695 — neuroscience — Posted on 2020-11-26
535 Differential impact of GABAA Receptors on Inhibitory connectivity for Superficial Pyramidal Neuron Responsiveness In Vivo
Tsai, Y.-C.; Hleihil, M.; Cramer, T.; Ferrari, K. D.; Barrett, M. J. P.; Bosshard, G.; Weber, B.; Stobart, J. L.; Tyagarajan, S. K.
10.1101/2020.11.25.397877 — neuroscience — Posted on 2020-11-26
536 3D segmentation of perivascular spaces on T1-weighted 3 Tesla MR images with a convolutional autoencoder and a U-shaped neural network
Boutinaud, P.; Tsuchida, A.; Laurent, A.; Adonias, F.; Hanifehlou, Z.; Nozais, V.; Verrecchia, V.; Lampe, L.; Zhang, J.; Zhu, Y.-C.; Tzourio, C.; Mazoyer, B.; Joliot, M.
10.1101/2020.11.25.397364 — neuroscience — Posted on 2020-11-26
538 Modelling optically pumped magnetometerinterference as a mean (magnetic) field
Tierney, T. M.; Alexander, N.; Mellor, S.; Holmes, N.; Seymour, R.; O'Neill, G. C.; Maguire, E. A.; Barnes, G. R.
10.1101/2020.11.25.397778 — neuroscience — Posted on 2020-11-26
539 The effect of ischaemic postconditioning on mucosal integrity and function in equine jejunal ischaemia
Verhaar, N.; Breves, G.; Hewicker-Trautwein, M.; Pfarrer, C.; Rohn, K.; Burmester, M.; Schnepel, N.; Neudeck, S.; Twele, L.; Kaestner, S.
10.1101/2020.11.25.397752 — pathology — Posted on 2020-11-26
549 Interpreting wide-band neural activity using convolutional neural networks
Frey, M.; Tanni, S.; Perrodin, C.; O'Leary, A.; Nau, M.; Kelly, J.; Banino, A.; Doeller, C. F.; Barry, C.
10.1101/871848 — neuroscience — Posted on 2020-11-26
552 An adaptive optics module for deep tissue multiphoton imaging in vivo
Rodriguez, C.; Chen, A.; Rivera, J. A.; Mohr, M. A.; Liang, Y.; Sun, W.; Milkie, D. E.; Bifano, T. G.; Chen, X.; Ji, N.
10.1101/2020.11.25.397968 — bioengineering — Posted on 2020-11-26
553 Deep learning-enhanced light-field imaging with continuous validation
Wagner, N.; Beuttenmueller, F.; Norlin, N.; Gierten, J.; Wittbrodt, J.; Weigert, M.; Hufnagel, L.; Prevedel, R.; Kreshuk, A.
10.1101/2020.07.30.228924 — bioengineering — Posted on 2020-11-26
554 Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis - Top-Down Mass Spectrometry (nCZE-TDMS)
Jooss, K.; Schachner, L. F.; Watson, R.; Gillespie, Z. B.; Howard, S. A.; Cheek, M. A.; Meiners, M. J.; Licht, J. D.; Keogh, M.-C.; Kelleher, N. L.
10.1101/2020.11.25.398925 — biochemistry — Posted on 2020-11-26
557 Direct Observation of the Mechanism of Antibiotic Resistance by Mix-and-Inject at the European XFEL
Pandey, S.; Calvey, G.; Katz, A. M.; Malla, T. N.; Koua, F.; Martin-Garcia, J.; Poudyal, I.; Yang, J.-H.; Vakili, M.; Yefanov, O.; Zielinski, K. A.; Bajt, S.; Awel, S.; Doerner, K.; Frank, M.; Gelisio, L.; Jernigan, R.; Kirkwood, H.; Kloos, M.; Koliyadu, J.; Mariani, V.; Miller, M. D.; Mills, G.; Nelson, G.; Olmos, J. L.; Sadri, A.; Sato, T.; Tolstikova, A.; Xu, W.; Ourmazd, A.; Spence, J. H. C.; Schwander, P.; Barty, A.; Chapman, H.; Fromme, P.; Mancuso, A.; Phillips, G.; Bean, R.; Pollack, L.; Schmidt, M.
10.1101/2020.11.24.396689 — biophysics — Posted on 2020-11-26
559 PLD2-phosphatidic acid recruit ESCRT-I to late endosomes for exosome biogenesis.
Egea-Jimenez, A. L.; Audebert, S.; Castro-Cruz, M.; Borg, J.-P.; David, G.; Camoin, L.; Zimmermann, P.
10.1101/2020.11.25.398396 — cell biology — Posted on 2020-11-26
560 Massively parallel interrogation of protein fragment secretability using SECRiFY reveals features influencing secretory system transit
Boone, M.; Ramasamy, P.; Zuallaert, J.; Bouwmeester, R.; Van Moer, B.; Maddelein, D.; Turan, D.; Hulstraert, N.; Eeckhout, H.; Vandermarliere, E.; Martens, L.; Degroeve, S.; De Neve, W.; Vranken, W.; Callewaert, N.
10.1101/241349 — molecular biology — Posted on 2020-11-26
561 Selective BCL-XLAntagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Ex Vivo Reservoirs
Ren, Y.; huang, s. h.; Macedo, A.; Ward, A.; Conce, W.; Klevorn, T.; Leyre, L.; Chan, D.; Truong, R.; Rohwetter, T.; Zumbo, P.; Dundar, F.; Betel, D.; Kovacs, C.; Benko, E.; Bosque, A.; Jones, B.
10.1101/2020.11.25.397679 — microbiology — Posted on 2020-11-26
562 Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids
Abuaita, B. H.; Lawrence, A.-L. E.; Berger, R. P.; Hill, D. R.; Huang, S.; Yadagiri, V. K.; Bons, B.; Fields, C.; Wobus, C. E.; Spence, J. R.; Young, V. B.; O'Riordan, M.
10.1101/2020.11.25.397620 — microbiology — Posted on 2020-11-26
563 Integration in or Near Oncogenes Plays Only a Minor Role in Determining the in Vivo Distribution of HIV Integration Sites Before or During Suppressive Antiretroviral Therapy
Coffin, J. M.; Bale, M.; Wells, D.; Guo, S.; Luke, B.; Zerbato, J. M.; Sobolewski, M. D.; Sia, T.; Shao, W.; Wu, X.; Maldarelli, F.; Kearney, M. F.; Mellors, J. W.; Hughes, S. H.
10.1101/2020.11.25.397653 — microbiology — Posted on 2020-11-26
565 Rapid shift in microbial community structure in a neutral hydrothermal hot spring from Costa Rica
Rojas-Gätjens, D.; Arce-Rodriguez, A.; Puente-Sanchez, F.; Avendano, R.; Libby, E.; Conejo-Barboza, G.; Mora-Amador, R.; Rojas-Jimenez, K.; Pieper, D. H.; Chavarria, M.
10.1101/2020.11.23.395137 — microbiology — Posted on 2020-11-26
567 Bradyrhizobium diazoefficiens USDA110 nodulation of Aeschynomene afraspera is associated with atypical terminal bacteroid differentiation and suboptimal symbiotic efficiency
Nicoud, Q.; Lamouche, F.; Chaumeret, A.; Balliau, T.; Le Bars, R.; Bourge, M.; Pierre, F.; Guerard, F.; Sallet, E.; Tuffigo, S.; Pierre, O.; DESSAUX, Y.; Gilard, F.; Gakiere, B.; Nagy, I.; Kereszt, A.; Zivy, M.; Mergaert, P.; Gourion, B.; Alunni, B.
10.1101/2020.11.24.397182 — microbiology — Posted on 2020-11-26
570 The HSPG Syndecan is a core organizer of cholinergic synapses in C. elegans
Zhou, X.; Vachon, C.; Cizeron, M.; Romatif, O.; Buelow, H.; Jospin, M.; Bessereau, J.-L.
10.1101/2020.11.25.395806 — neuroscience — Posted on 2020-11-26
571 CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
Hosokawa, T.; Liu, P.-W.; Cai, Q.; Ferreira, J. S.; Levet, F.; Butler, C.; Sibarita, J.-B.; Choquet, D.; Groc, L.; Hosy, E.; Zhang, M.; Hayashi, Y.
10.1101/2020.11.25.397091 — neuroscience — Posted on 2020-11-26
572 A Deep Graph Neural Network Architecture for Modelling Spatio-temporal Dynamics in resting-state functional MRI Data
Azevedo, T.; Campbell, A.; Romero-Garcia, R.; Passamonti, L.; Bethlehem, R. A. I.; Lio, P.; Toschi, N.
10.1101/2020.11.08.370288 — neuroscience — Posted on 2020-11-26
573 Intronic enhancer region governs transcript-specific BDNF expression in neurons
Tuvikene, J.; Esvald, E.-E.; Rähni, A.; Uustalu, K.; Zhuravskaya, A.; Avarlaid, A.; Makeyev, E. V.; Timmusk, T.
10.1101/2020.11.25.398156 — neuroscience — Posted on 2020-11-26
575 Rest functional brain maturation during the first year of life
Lemaitre, H.; Auge, P.; Saitovitch, A.; Vincon-Leite, A.; Tacchella, J.-M.; Fillon, L.; Calmon, R.; Dangouloff-Ros, V.; Levy, R.; Grevent, D.; Brunelle, F.; Boddaert, N.; Zilbovicius, M.
10.1101/760843 — neuroscience — Posted on 2020-11-26
577 ATP drives efficient terpene biosynthesis in marine thraustochytrids
Zhang, A.; Mernitz, K. A.; Wu, C.; Xiong, W.; He, Y.; Wang, G.; Wang, X.
10.1101/2020.11.20.391870 — systems biology — Posted on 2020-11-26
582 Chemical composition and insecticidal activity of Aeollanthus pubescens Benth leaf essential oil on the malaria vector Anopheles gambiae (Diptera: Culicidae).
Bohounton, R. B.; Djogbenou, L.; Djihinto, O. Y.; Dedome, O. S.-L.; Sovegnon, P. M.; Barea, B.; Adomou, A.; Villeneuve, P.; Tchobo, F. P.
10.1101/2020.11.25.397588 — pharmacology and toxicology — Posted on 2020-11-26
583 Fat Tissue Regulates the Pathogenesis and Severity of Cardiomyopathy in Murine Chagas Disease
Nagajyothi, J. F.; Lizardo, K.; Ayyappan, J. P.; Oswal, N.; Weiss, L. M.; Scherer, P. E.
10.1101/2020.11.25.397596 — pathology — Posted on 2020-11-26
584 RRM2 is a target for synthetic lethal interactions with replication stress checkpoint addiction in high-risk neuroblastoma
Nunes, C.; Depestel, L.; Mus, L. M.; Keller, K. M.; Delhaye, L.; Louwagie, A.; Rishfi, M.; Dolman, E. M.; Olexiouk, V.; Bartenhagen, C.; Devloed, F.; Sanders, E.; Eggermont, A.; Van Laere, J.; De Smet, E.; Van Loocke, W.; Morscio, J.; Loontiens, S.; Depuydt, P.; Decaesteker, B.; Tilleman, L.; Van Nieuwerburgh, F.; Deforce, D.; De Wilde, B.; Van Vlierberghe, P.; Vermeirssen, V.; Goossens, S.; Eyckerman, S.; Van Neste, C.; Roberts, S.; Fischer, M.; Molenaar, J. J.; Durinck, K.; Speleman, F.
10.1101/2020.11.25.397323 — cancer biology — Posted on 2020-11-26
587 Transient active osmotic swelling of epithelium upon curvature induction
Tomba, C.; Luchnikov, V.; Barberi, L.; Blanch-Mercader, C.; Roux, A.
10.1101/2020.11.25.398107 — biophysics — Posted on 2020-11-26
589 Direct information estimation from cryo-EM Movies with CARYON
Ramlaul, K.; Burt, A.; de Martin Garrido, N.; MacDonald, J.; Palmer, C.; Jakobi, A.; Aylett, C. H. S.
10.1101/2020.11.25.398891 — biophysics — Posted on 2020-11-26
590 AN EPILEPSY-CAUSING MUTATION LEADS TO CO-TRANSLATIONAL MISFOLDING
Urrutia, J.; Aguado, A.; Gomis-Perez, C.; Muguruza-Montero, A.; R. Ballesteros, O.; Zhang, J.; Nunez, E.; Malo, C.; Chung, H. J.; Leonardo, A.; Bergara, A.; Villarroel, A.
10.1101/2020.11.25.398222 — biophysics — Posted on 2020-11-26
591 How mu-Opioid Receptor Recognizes Fentanyl
Vo, Q. N.; Mahinthichaichan, P.; Shen, J.; Ellis, C. R.
10.1101/2020.08.16.253013 — biophysics — Posted on 2020-11-26
592 N-terminal VP1 truncations favor T=1 norovirus-like particles
Pogan, R.; Weiss, V. U.; Bond, K.; Duelfer, J.; Krisp, C.; Lyktey, N.; Mueller-Guhl, J.; Zorrato, S.; Allmaier, G.; Jarrold, M. F.; Munoz-Fontela, C.; Schlueter, H.; Uetrecht, C.
10.1101/2020.11.25.396499 — biophysics — Posted on 2020-11-26
595 Automated Segmentation of Fractured Distal Radii by 3D Geodesic Active Contouring of in vivo HR-pQCT Images
Ohs, N.; Collins, C. J.; Tourolle, D. C.; Atkins, P. R.; Schroeder, B.; Blauth, M.; Christen, P.; Müller, R.
10.1101/2020.10.14.339739 — bioengineering — Posted on 2020-11-26
596 Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U.; Karapetsas, A.; Nirujogi, R. S.; Mathea, S.; Pal, P.; Lis, P.; Taylor, M.; Purlyte, E.; Gourlay, R.; Dorward, M.; Weidlich, S.; Toth, R.; Polinski, N. K.; Knapp, S.; Tonelli, F.; Alessi, D. R.
10.1101/2020.11.25.397836 — biochemistry — Posted on 2020-11-26
597 CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation
Brilot, A. F.; Lyon, A.; Zelter, A.; Viswanath, S.; Maxwell, A.; MacCoss, M. J.; Muller, E. G.; Sali, A.; Davis, T. N.; Agard, D. A.
10.1101/2020.11.21.392803 — biochemistry — Posted on 2020-11-26
601 Common allotypes of ER aminopeptidase 1 have substrate-dependent and highly variable enzymatic properties
Jonathan, H. P.; Temponeras, I.; Kuiper, J.; Cortes, A.; Korczynska, J.; Kitchen, S.; Stratikos, E.
10.1101/2020.11.19.389403 — biochemistry — Posted on 2020-11-26
602 Extensive phylogenies of human development reveal variable embryonic patterns
Coorens, T. H. H.; Moore, L.; Robinson, P. S.; Sanghvi, R.; Christopher, J.; Hewinson, J.; Cagan, A.; Oliver, T.; Neville, M.; Hooks, Y.; Noorani, A.; Mitchell, T. J.; Fitzgerald, R.; Campbell, P.; Martincorena, I.; Rahbari, R.; Stratton, M.
10.1101/2020.11.25.397828 — genomics — Posted on 2020-11-26
603 Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples.
O'Brien, C. E.; Oliveira Pacheco, J. M.; O Cinneide, E.; Haase, M. A. B.; Hittinger, C. T.; Rogers, T. R.; Zaragoza, O.; Bond, U.; Butler, G.
10.1101/2020.11.25.397612 — genomics — Posted on 2020-11-26
608 Mediterranean Diet Reduces Monocyte Inflammatory Gene Expression and Influences Social Behavior in Nonhuman Primates
Johnson, C. S. C.; Shively, C. A.; Michalson, K. T.; Lea, A. J.; DeBo, R. J.; Howard, T. D.; Hawkins, G. A.; Appt, S. E.; Liu, Y.; McCall, C. E.; Herrington, D.; Register, T. C.; Snyder-Mackler, N.
10.1101/2020.01.27.917567 — genomics — Posted on 2020-11-26
611 Flexible multivariate linear mixed models for structured multiple traits
Kim, H.; Farage, G.; Lovell, J. T.; Mckay, J. K.; Juenger, T. E.; Sen, S.
10.1101/2020.03.27.012690 — genetics — Posted on 2020-11-26
612 DILS : Demographic Inferences with Linked Selection by using ABC
Fraisse, C.; Popovic, I.; Mazoyer, C.; Spataro, B.; Delmotte, S.; Romiguier, J.; Loire, E.; Simon, A.; Galtier, N.; Duret, L.; Bierne, N.; Vekemans, X.; Roux, C.
10.1101/2020.06.15.151597 — evolutionary biology — Posted on 2020-11-26
621 No Evidence for a Difference in 2D:4D Ratio between Youth with Elevated Prenatal Androgen Exposure due to Congenital Adrenal Hyperplasia and Controls
Nave, G.; Koppin, C. M.; Manfredi, D.; Richards, G.; Watson, S. J.; Geffner, M. E.; Yong, J. E.; Kim, R.; Ross, H. M.; Serrano-Gonzalez, M.; Kim, M. S.
10.1101/2020.05.07.082529 — developmental biology — Posted on 2020-11-26
623 Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
Rodermund, L.; Coker, H.; Oldenkamp, R.; Wei, G.; Bowness, J.; Rajkumar, B.; Nesterova, T. B.; Pinto, D.; Schermelleh, L.; Brockdorff, N.
10.1101/2020.11.24.396473 — developmental biology — Posted on 2020-11-26
625 Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model for Phospholamban R14del cardiomyopathy
Kamel, S.; van Opbergen, C.; Koopman, L.; Verkerk, A.; Onderwater, Y.; Polidoro Pontalti, C.; Chocron, S.; Vos, M.; de Boer, T.; van Veen, T.; Bakkers, J.
10.1101/2020.11.25.397422 — cell biology — Posted on 2020-11-26
626 Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans
Rooney, J. P.; Hershberger, K. A.; Turner, E. A.; Donoghue, L. J.; Maurer, L. L.; Ryde, I. T.; Kim, J. J.; Joglekar, R.; Hibshman, J. D.; Smith, L. L.; Bhatt, D. P.; Ilkayeva, O. R.; Hirschey, M. D.; Meyer, J. N.
10.1101/2020.11.25.398164 — cell biology — Posted on 2020-11-26
627 Automated and customizable quantitative image analysis of whole C. elegans germlines
Toraason, E.; Adler, V. L.; Kurhanewicz, N. A.; DiNardo, A.; Saunders, A. M.; Cahoon, C. K.; Libuda, D. E.
10.1101/2020.11.25.398685 — cell biology — Posted on 2020-11-26
629 The 20S proteasome activator PA28γ controls the compaction of chromatin
Fesquet, D.; Lleres, D.; Grimaud, C.; Vigano, C.; Mechali, F.; Boulon, S.; Coux, O.; Bonne-Andrea, C.; Baldin, V.
10.1101/716332 — cell biology — Posted on 2020-11-26
630 Integrative Single-cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Haematopoiesis
Ranzoni, A. M.; Tangherloni, A.; Berest, I.; Riva, S. G.; Myers, B.; Strzelecka, P. M.; Xu, J.; Panada, E.; Mohorianu, I.; Zaugg, J. B.; Cvejic, A.
10.1101/2020.05.06.080259 — cell biology — Posted on 2020-11-26
631 CtIP -mediated alternative mRNA splicing finetunes the DNA damage response
Prados-Carvajal, R.; Rodriguez-Real, G.; Gutierrez-Pozo, G.; Huertas, P.
10.1101/849547 — molecular biology — Posted on 2020-11-26
636 Local Field Potentials in a Pre-motor Region Predict Learned Vocal Sequences
Brown, D. E.; Chavez, J. I.; Nguyen, D. H.; Kadwory, A.; Voytek, B.; Arneodo, E.; Gentner, T. Q.; Gilja, V.
10.1101/2020.06.30.179861 — neuroscience — Posted on 2020-11-26
640 Evaluation and refinement of sample preparation methods for extracellular matrix proteome coverage
McCabe, M. C.; Schmitt, L. R.; Hill, R. C.; Dzieciatkowska, M.; Maslanka, M.; Daamen, W. F.; van Kuppevelt, T. H.; Hof, D. J.; Hansen, K. C.
10.1101/2020.11.25.391946 — biochemistry — Posted on 2020-11-25
643 Efficient GNE myopathy disease modeling with mutation specific phenotypes in human pluripotent stem cells by base editors
Park, J.-C.; Kim, J.; Jang, H.-K.; Lee, S.-Y.; Kim, K.-T.; Park, S.; Lee, H. S.; Choi, H.-J.; Park, S.-J.; Moon, S.-H.; Bae, S.; Cha, H.-J.
10.1101/2020.11.25.397711 — developmental biology — Posted on 2020-11-25
644 A developmentally programmed splicing failure attenuates the DNA damage response during mammalian zygotic genome activation
Waytt, C. D. R.; Pernaute, B.; Gohr, A.; Miret-Cuesta, M.; Goyeneche, L.; Rovira, Q.; Bogdanovic, O.; Bonnal, S.; Irimia, M.
10.1101/2020.11.25.397794 — developmental biology — Posted on 2020-11-25
646 The replicative amplification of MITEs and their impact on rice trait variability
Castanera, R.; Vendrell-Mir, P.; Bardil, A.; Carpentier, M. C.; Panaud, O.; Casacuberta, J.
10.1101/2020.10.01.322784 — molecular biology — Posted on 2020-11-25
647 Pupal cannibalism by worker honey bees contributes to the spread of Deformed wing virus.
Posada-Florez, F.; Lamas, Z. S.; Hawthorne, D. J.; Chen, Y.; Evans, J. D.; Ryabov, E. V.
10.1101/2020.11.25.396259 — microbiology — Posted on 2020-11-25
648 Selective transport of fluorescent proteins into the phage nucleus
Nguyen, K. T.; Sugie, J.; Khanna, K.; MacKennon, E. E.; Birkholz, E. A.; Lee, J.; Beierschmitt, C.; Villa, E.; Pogliano, J.
10.1101/2020.11.25.398438 — microbiology — Posted on 2020-11-25
649 Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile
Boudry, P.; Piattelli, E.; Drouineau, E.; Peltier, J.; Boutserin, A.; Lejars, M.; Hajnsdorf, E.; Monot, M.; Dupuy, B.; Martin-Verstraete, I.; Gautheret, D.; Toffano-Nioche, C.; SOUTOURINA, O.
10.1101/2020.11.25.398065 — microbiology — Posted on 2020-11-25
650 Regulatory roles of 5' UTR and ORF-internal RNAs detected by 3' end mapping
Adams, P. P.; Baniulyte, G.; Esnault, C.; Chegireddy, K.; Singh, N.; Monge, M.; Dale, R. K.; Storz, G.; Wade, J. T.
10.1101/2020.07.18.207399 — microbiology — Posted on 2020-11-25
652 mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination
Della-Flora Nunes, G.; Wilson, E. R.; Hurley, E.; He, B.; O'Malley, B. W.; Poitelon, Y.; Wrabetz, L.; Feltri, M. L.
10.1101/2020.11.25.398032 — neuroscience — Posted on 2020-11-25
653 Molecular and functional architecture of striatal dopamine release sites
Banerjee, A.; Imig, C.; Balakrishnan, K.; Kershberg, L.; Lipstein, N.; Uronen, R.-L.; Wang, J.; Cai, X.; Benseler, F.; Rhee, J. S.; Cooper, B. H.; Liu, C.; Wojcik, S. M.; Brose, N.; Kaeser, P. S.
10.1101/2020.11.25.398255 — neuroscience — Posted on 2020-11-25
655 The C99 domain of the amyloid precursor protein is a disordered membrane phase-preferring protein
Capone, R. F.; Tiwari, A.; Hadziselimovic, A.; Peskova, Y.; Hutchinson, J. M.; Sanders, C. R.; Kenworthy, A. K.
10.1101/2020.11.25.397893 — neuroscience — Posted on 2020-11-25
656 Brain Network Mechanisms of Visual Shape Completion
Keane, B. P.; Barch, D. M.; Mill, R. D.; Silverstein, S. M.; Krekelberg, B.; Cole, M. W.
10.1101/2020.08.03.233403 — neuroscience — Posted on 2020-11-25
657 Changes in epithelial proportions and transcriptional state underlie major premenopausal breast cancer risks
Murrow, L. M.; Weber, R. J.; Caruso, J.; McGinnis, C. S.; Phong, K.; Gascard, P.; Borowsky, A. D.; Desai, T. A.; Thomson, M.; Tlsty, T. D.; Gartner, Z. J.
10.1101/430611 — systems biology — Posted on 2020-11-25
659 Attitudes and Practices of Open Data, Preprinting, and Peer-review - a Cross Sectional Study on Croatian Scientists
Bazdaric, K.; Vrkic, I.; Arh, E.; Mavrinac, M.; Gligora Markovic, M.; Bilic-Zulle, L.; Stojanovski, J.; Malicki, M.
10.1101/2020.11.25.395376 — scientific communication and education — Posted on 2020-11-25
661 Silencing SmD1 in Solanaceae alters susceptibility to root-knot nematodes
Mejias, J.; Chen, Y.; Truong, N.-M.; Mulet, K.; Jaubert-Possamai, S.; Abad, P.; Favery, B.; Quentin, M.
10.1101/2020.11.25.398149 — plant biology — Posted on 2020-11-25
664 Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids
Aleshin, A. E.; Yao, Y.; Iftikar, A.; Bobkov, A. A.; Yu, J.; Cadwell, G.; Klein, M.; Dong, C.; Bankston, L. A.; Liddington, R. C.; Im, W.; Powis, G.; Marassi, F. M.
10.1101/2020.11.25.387084 — biochemistry — Posted on 2020-11-25
665 Comprehensive benchmarking of single cell RNA sequencing technologies for characterizing cellular perturbation
Verboom, K.; Assefa, A. T.; Yigit, N.; Anckaert, J.; Vandamme, N.; Rombaut, D.; Saeys, Y.; Thas, O.; Speleman, F.; Durinck, K.; Vandesompele, J.
10.1101/2020.11.25.396523 — molecular biology — Posted on 2020-11-25
668 Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection
Kamel, W.; Noerenberg, M.; Cerikan, B.; Chen, H.; Järvelin, A. I.; Kammoun, M.; Lee, J.; Shuai, N.; Garcia-Moreno, M.; Andrejeva, A.; Deery, M. J.; Neufeldt, C. J.; Cortese, M.; Knight, M. L.; Lilley, K. S.; Martinez, J.; Davis, I.; Bartenschlager, R.; Mohammed, S.; Castello, A.
10.1101/2020.11.25.398008 — microbiology — Posted on 2020-11-25
669 Controlling membrane barrier during bacterial type-III protein secretion
Hüsing, S.; van Look, U.; Güse, A.; Galvez, E. J. C.; Charpentier, E.; Blair, D. F.; Erhardt, M.; Renault, T. T.
10.1101/2020.11.25.397760 — microbiology — Posted on 2020-11-25
670 3D8, a nucleic acid-hydrolyzing scFv, confers antiviral activity against SARS-CoV-2 and multiple coronaviruses in vitro
Lee, G.; Budhathoki, S.; Choi, H. S.; Oh, K.-j.; Lee, G.-Y.; Ham, Y. K.; Kim, Y. J.; Lim, Y. R.; Hoang, P. T.; Lee, Y.; Lim, S.-W.; Kim, J.-M.; Cho, S.; Song, J.-W.; Lee, S.; Kim, W.-K.
10.1101/2020.11.25.398909 — microbiology — Posted on 2020-11-25
671 A functional module states framework reveals cell states for drug and target prediction
Qin, G.; Knijnenburg, T.; Gibbs, D.; Moser, R.; Monnat, R. J.; Kemp, C.; Shmulevich, I.
10.1101/2020.11.24.394932 — systems biology — Posted on 2020-11-25
673 Overall patient's survival of glioblastoma associated to molecular markers: a pan-proteomic prospective study
Drelich, L.; Duhamel, M.; Wisztorski, M.; Aboulouard, S.; Gimeno, J.-p.; Caux, P.-d.; Ogrinc, N.; Devos, P.; Cardon, T.; Weller, M.; Escande, F.; Zairi, F.; Maurage, C.-A.; Fournier, I.; Le rhun, E.; Salzet, M.
10.1101/2020.11.24.397117 — cancer biology — Posted on 2020-11-25
675 phiC31 integrase for recombination mediated single copy insertion and genome manipulation in C. elegans
Yang, F.-J.; Chen, C.-N.; Chang, T.; Cheng, T.-W.; Chang, N.-C.; Kao, C.-Y.; Lee, C.-C.; Huang, Y.-C.; Chan, S.-P.; Wang, J.
10.1101/2020.11.25.398784 — genetics — Posted on 2020-11-25
678 A versatile human intestinal organoid-derived epithelial monolayer model for the study of enteric pathogens
Nickerson, K. P.; Llanos-Chea, A.; Ingano, L.; Serena, G.; Miranda-Ribera, A.; Perlman, M.; Lima, R.; Sztein, M. B.; Fasano, A.; Senger, S.; Faherty, C. S.
10.1101/2020.11.24.397141 — microbiology — Posted on 2020-11-25
680 Intracellular localisation of Mycobacterium tuberculosis affects antibiotic efficacy
Santucci, P.; Greenwood, D.; Fearns, A.; Chen, K.; Jiang, H.; Gutierrez, M. G.
10.1101/2020.11.25.398636 — microbiology — Posted on 2020-11-25
681 Th17 cells provide direct protective effects that limit stomach parasite burden following orogastric mucosal Trypanosoma cruzi infection
Cai, C. W.; Eickhoff, C. S.; Meza, K. A.; Blase, J. R.; Audette, R. E.; Chan, D. H.; Bockerstett, K. A.; DiPaolo, R. J.; Hoft, D. F.
10.1101/2020.11.24.397257 — immunology — Posted on 2020-11-25
682 RpoS Contributes to Successful Opportunistic Colonization by Human Enteric Pathogens during Plant Disease
Lovelace, A. H.; Lee, S.; Downs, D. M.; Soufi, Z.; Bota, P.; Preston, G. M.; Kvitko, B. H.
10.1101/2020.11.24.397208 — pathology — Posted on 2020-11-25
685 MIPMLP - Microbiome Pre-processing Machine Learning Pipeline.
Jasner, Y.; belogolovski, A.; Ben Izhak, M.; Koren, O.; Louzoun, Y.
10.1101/2020.11.24.397174 — microbiology — Posted on 2020-11-25
687 Specific norovirus interaction with Lewis x and Lewis a on human intestinal inflammatory mucosa during refractory inflammatory bowel disease
Tarris, G.; de Rougemont, A.; Estienney, M.; Charkaoui, M.; Mouillot, T.; Bonnotte, B.; Michiels, C.; Martin, L.; Belliot, G.
10.1101/2020.11.24.397125 — microbiology — Posted on 2020-11-25
688 Auxin requirements for a meristematic state in roots depend on a dual brassinosteroid function
Ackerman-Lavert, M.; Fridman, Y.; Matosevich, R.; Khandal, H.; Friedlander-Shani, L.; Vragovic, K.; Ben-El, R.; Horev, G.; Efroni, I.; Savaldi-Goldstein, S.
10.1101/2020.11.24.395483 — plant biology — Posted on 2020-11-25
690 Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage
Ge, W.; Liang, X.; Zhang, F.; Xu, L.; Xiang, N.; Sun, R.; Liu, W.; Xue, Z.; Yi, X.; Wang, B.; Zhu, J.; Lu, C.; Zhan, X.; Chen, L.; Wu, Y.; Zheng, Z.; Gong, W.; Wu, Q.; Yu, J.; Ye, Z.; Teng, X.; Huang, S.; Zheng, S.; Liu, T.; Yuan, C.; Guo, T.
10.1101/2020.11.24.395426 — bioinformatics — Posted on 2020-11-25
691 Sparse Epistatic Regularization of Deep Neural Networks for Inferring Fitness Functions
Aghazadeh, A.; Nisonoff, H.; Ocal, O.; Huang, Y.; Koyluoglu, O. O.; Listgarten, J.; Ramchandran, K.
10.1101/2020.11.24.396994 — bioinformatics — Posted on 2020-11-25
692 A method to quantify autonomic nervous system function in healthy, able-bodied individuals
Debnath, S.; Levy, T. J.; Bellehsen, M.; Schwartz, R. M.; Barnaby, D. P.; Zanos, S.; Volpe, B. T.; Zanos, T. P.
10.1101/2020.11.24.396309 — bioengineering — Posted on 2020-11-25
693 Using seasonal genomic changes to understand historical adaptation: parallel selection on stickleback in highly-variable estuaries
Garcia-Elfring, A.; Paccard, A.; Thurman, T. J.; Wasserman, B. A.; Palkovacs, E. P.; Hendry, A. P.; Barrett, R. D.
10.1101/2020.11.24.396291 — genomics — Posted on 2020-11-25
696 SARS-CoV-2 utilizes a multipronged strategy to suppress host protein synthesis
Finkel, Y.; Gluck, A.; Winkler, R.; Nachshon, A.; Mizrahi, O.; Lubelsky, Y.; Zuckerman, B.; Slobodin, B.; Yahalom-Ronen, Y.; Tamir, H.; Ulitsky, I.; Israely, T.; Paran, N.; Schwartz, M.; Stern-Ginossar, N.
10.1101/2020.11.25.398578 — microbiology — Posted on 2020-11-25
697 COUNTEN an AI-driven tool for rapid, and objective structural analyses of the Enteric Nervous System
Kobayashi, Y.; Bukowski, A.; Das, S.; Espenel, C.; Gomez-Frittelli, J.; Wagle, N.; Bakhshi, S.; Saha, M.; Kaltschmidt, J. A.; Venkataraman, A.; Kulkarni, S.
10.1101/2020.11.24.396408 — neuroscience — Posted on 2020-11-25
700 Bile acid excess impairs thermogenic function in brown adipose tissue
Zhou, W.; VanDuyne, P.; Zhang, C.; Riessen, R.; Barragan, M.; Rowitz, B. M.; Teran-Garcia, M.; Boppart, S. A.; Anakk, S.
10.1101/2020.11.24.396895 — physiology — Posted on 2020-11-25
703 Learning epistatic polygenic phenotypes with Boolean interactions
Behr, M.; Kumbier, K.; Cordova-Palomera, A.; Aguirre, M.; Ashley, E.; Butte, A.; Arnaout, R.; Brown, J. B.; Preist, J.; Yu, B.
10.1101/2020.11.24.396846 — bioinformatics — Posted on 2020-11-25
704 ProCbA: Protein Function Prediction based on Clique Analysis
Khanteymoori, A.; Ghajehlo, M. B.; Behrouzinia, S.; Olyaee, M. H.
10.1101/2020.11.24.396432 — bioinformatics — Posted on 2020-11-25
707 Neuroskeletal effects of chronic bioelectric nerve stimulation in health and diabetes
Beeve, A. T.; Shen, I.; Zhang, X.; Magee, K.; Yan, Y.; MacEwan, M.; Scheller, E. L.
10.1101/2020.11.24.396143 — bioengineering — Posted on 2020-11-25
710 What are the demographic consequences of a seed bank stage for columnar cacti?
Arroyo-Cosultchi, G.; Mandujano, M. C.; Salguero-Gomez, R.; Martinez, A. J.; Golubov, J.
10.1101/2020.11.24.396374 — ecology — Posted on 2020-11-25
717 Sleep is required for odor exposure to consolidate memory and remodel olfactory synapses.
Munoz-Lobato, F.; Benedetti, K. L.; Farah, F.; Chandra, R.; Bokka, A.; Brueggemann, C.; Saifuddin, F. M.; Nordquist, S. K.; Li, J.; Chang, E.; Varshney, A.; Jiminez, V.; Andersen, K. E.; Baradwaj, A.; Miller, J. M.; Dunn, R. L.; Tsujimoto, B.; Duong, A.; Tran, A.; Churgin, M.; Fang-Yen, C.; Bremer, M.; Kato, S.; VanHoven, M.; L'Etoile, N.
10.1101/2020.11.24.395228 — neuroscience — Posted on 2020-11-25
720 distinct: a novel approach to differential distribution analyses
Tiberi, S.; Crowell, H. L.; Weber, L. M.; Samartsidis, P.; Robinson, M. D.
10.1101/2020.11.24.394213 — bioinformatics — Posted on 2020-11-25
722 Evolutionary analysis of SARS-CoV-2 spike protein for its different clades
Pereson, M. J.; Flichman, D.; Martinez, A.; Bare, P.; Garcia, G.; Di Lello, F.
10.1101/2020.11.24.396671 — evolutionary biology — Posted on 2020-11-25
724 SpheroidPicker: An Automated 3D cell culture manipulator robot using deep learning
Grexa, I.; Diosdi, A.; Kriston, A.; Moshkov, N.; Harmati, M.; Buzas, K.; Pietiainen, V.; Koos, K.; Hovath, P.
10.1101/2020.11.25.397331 — bioengineering — Posted on 2020-11-25
726 Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U.; Karapetsas, A.; Nirujogi, R. S.; Mathea, S.; Pal, P.; Lis, P.; Taylor, M.; Purlyte, E.; Gourlay, R.; Dorward, M.; Weidlich, S.; Toth, R.; Knapp, S.; Tonelli, F.; Alessi, D. R.
10.1101/2020.11.25.397836 — biochemistry — Posted on 2020-11-25
727 Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics
Markin, C. J.; Mokhtari, D. A.; Sunden, F.; Appel, M. J.; Akiva, E.; Longwell, S.; Sabatti, C.; Herschlag, D.; Fordyce, P. M.
10.1101/2020.11.24.383182 — biochemistry — Posted on 2020-11-25
728 The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo
Mueller, C.; Obermann, W.; Karl, N.; Wendel, H. G.; Taroncher-Oldenburg, G.; Pleschka, S.; Hartmann, R. K.; Gruenweller, A.; Ziebuhr, J.
10.1101/2020.11.24.389627 — molecular biology — Posted on 2020-11-25
730 Novel SARS-CoV-2 Whole-genome sequencing technique using Reverse Complement PCR enables easy, fast and accurate outbreak analysis in hospital and community settings
Wolters, F.; Coolen, J. P. M.; Tostmann, A.; van Groningen, L. F. J.; Bleeker-Rovers, C. P.; Tan, E. C. T. H.; van der Geest-Blankert, N.; Hautvast, J. L. A.; Hopman, J.; Wertheim, H. F. L.; Rahamat-Langendoen, J. C.; Storch, M.; Melchers, W. J. G.
10.1101/2020.10.29.360578 — microbiology — Posted on 2020-11-25
731 The structural connectome constrains fast brain dynamics
Sorrentino, P.; Seguin, C.; Rucco, R.; Liparoti, M.; Troisi Lopez, E.; Bonavita, S.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.; Zalesky, A.
10.1101/2020.11.25.393017 — neuroscience — Posted on 2020-11-25
734 Rapid Detection of VanA/B-Producing Vancomycin-Resistant enterococci using Lateral Flow Immunoassay from colonies and blood culture
Oueslati, S.; VOLLAND, H.; Cattoir, V.; Bernabeu, S.; Girlich, D.; dulac, d.; Plaisance, M.; boutigny, l.; Dortet, L.; Simon, S.; Naas, T.
10.1101/2020.11.23.395293 — microbiology — Posted on 2020-11-25
735 Double Lock of a Potent Human Monoclonal Antibody against SARS-CoV-2
Wang, X.; Qin, C.; Wang, Y.; Rao, Z.; Xie, L.; Zhu, L.; Deng, Y.-Q.; Zhang, R.-r.; Cui, Z.; Sun, C.-Y.; Fan, C.-F.; Xing, X.; Huang, W.; Chen, Q.; Zhang, N.-N.; Ye, Q.; Cao, T.-S.; Wang, N.; Wang, L.; Cao, L.; Wang, H.; Kong, D.; Ma, J.; Luo, C.; Zhang, Y.; Nie, J.; Sun, Y.; Lv, Z.; Shaw, N.; Li, Q.; Li, X.-F.; Hu, J.
10.1101/2020.11.24.393629 — biophysics — Posted on 2020-11-25
736 Crystal structure of chloroplastic thioredoxin z defines a novel type-specific target recognition
Le Moigne, T.; Gurrieri, L.; Crozet, P.; Marchand, C. H.; Zaffagnini, M.; Sparla, F.; Lemaire, S. D.; Henri, J.
10.1101/2020.11.24.396572 — biochemistry — Posted on 2020-11-25
737 A Nasal Spray Solution of Grapefruit Seed Extract plus Xylitol Displays Virucidal Activity Against SARS-Cov-2 In Vitro
Ferrer, G. A.; Betancour, A.; Go, C. C.; Vazquez, H.; Westover, J. B.; Cagno, V.; Tapparel, C.; Sanchez-Gonzalez, M. A.
10.1101/2020.11.23.394114 — cell biology — Posted on 2020-11-25
738 Polymerization of misfolded protein lowers CX3CR1 expression in human PBMCs
Tumpara, S.; Ballmaier, M.; Wrenger, S.; König, M.; Lehmann, M.; Lichtinghagen, R.; Martinez-Delgado, B.; DeLuca, D.; Jedicke, N.; Welte, T.; Fromme, M.; Strnad, P.; Stolk, J.; Janciauskiene, S.
10.1101/2020.11.24.395640 — cell biology — Posted on 2020-11-25
740 The novel PII-interacting protein PirA regulates flux into the cyanobacterial ornithine-ammonia cycle
Bolay, P.; Muro-Pastor, I.; Rozbeh, R.; Timm, S.; Hagemann, M.; Florencio, F. J.; Forchhammer, K.; Klähn, S.
10.1101/2020.11.23.395327 — microbiology — Posted on 2020-11-25
741 Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are key features of alpacas resolving MERS-CoV infection
Te, N.; Rodon, J.; Ballester, M.; Perez, M.; Pailler-Garcia, L.; Segales, J.; Vergara-Alert, J.; Bensaid, A.
10.1101/2020.11.23.395301 — immunology — Posted on 2020-11-25
742 Identification of QTL and Underlying Genes for Root System Architecture associated with Nitrate Nutrition in Hexaploid Wheat
Griffiths, M. D.; Atkinson, J. A.; Gardiner, L.-J.; Swarup, R.; Pound, M. P.; Wilson, M. H.; Bennett, M. J.; Wells, D. M.
10.1101/591529 — plant biology — Posted on 2020-11-25
743 First results on diversity patterns and selective sweeps in a Southeast European panel of maize inbred lines as combined with two West European panels
Galic, V.; Anđelkovic, V.; Kravic, N.; Grcic, N.; Ledencan, T.; Jambrovic, A.; Zdunic, Z.; Nicolas, S. D.; Charcosset, A.; Satovic, Z.; Simic, D.
10.1101/2020.11.24.376087 — genetics — Posted on 2020-11-25
744 Impacts of water quality on Acropora coral settlement: The relative importance of substrate quality and light
Ricardo, G. F.; Harper, C. E.; Negri, A. P.; Luter, H. M.; Abdul Wahab, M. A.; Jones, R. J.
10.1101/2020.11.19.390724 — ecology — Posted on 2020-11-25
746 Modeling pronoun resolution in the brain
Li, J.; Luh, W.-M.; Pylkkanen, L.; Yang, Y.; Hale, J.
10.1101/2020.11.24.396598 — neuroscience — Posted on 2020-11-25
749 Longitudinal white matter changes associated with cognitive training
Nichols, E. S.; Erez, J.; Stojanoski, B.; Lyons, K. M.; Witt, S. T.; Mace, C. A.; Khalid, S.; Owen, A. M.
10.1101/2020.11.24.396119 — neuroscience — Posted on 2020-11-25
761 Chromatin Fiber Folding Represses Transcription and Loop Extrusion in Quiescent Cells
Swygert, S. G.; Lin, D.; Portillo-Ledesma, S.; Lin, P.-Y.; Hunt, D. R.; Kao, C.-F.; Schlick, T.; Noble, W. S.; Tsukiyama, T.
10.1101/2020.11.24.396713 — molecular biology — Posted on 2020-11-24
763 Isolation and chacterisation of Klebsiella phages for phage therapy
Townsend, E.; Kelly, L.; Gannon, L.; Muscatt, G.; Dunstan, R.; Michniewski, S.; Sapkota, H.; Kiljunen, S. J.; Kolsi, A.; Skurnik, M.; Lithgow, T.; MIllard, A. D.; Jameson, E.
10.1101/2020.07.05.179689 — microbiology — Posted on 2020-11-24
764 Patterns of neural correlations in visual cortex vary with the number of objects
Jun, N. Y.; Ruff, D. A.; Kramer, L. E.; Bowes, B.; Tokdar, S. T.; Cohen, M. R.; Groh, J. M.
10.1101/777912 — neuroscience — Posted on 2020-11-24
772 ANGPTL4 from adipose, but not liver, is responsible for regulating plasma triglyceride partitioning
Spitler, K. M.; Shetty, S. K.; Cushing, E. M.; Sylvers-Davie, K. L.; Davies, B. S. J.
10.1101/2020.06.02.106815 — physiology — Posted on 2020-11-24
773 SUN-MKL1 crosstalk regulates nuclear deformation and fast motility of breast carcinoma cells in fibrillar ECM micro-environment
Sharma, V. P.; Williams, J.; Leung, E.; Sanders, J.; Eddy, R.; Castracane, J.; Oktay, M. H.; Entenberg, D.; Condeelis, J. S.
10.1101/2020.11.24.396390 — cancer biology — Posted on 2020-11-24
774 Peptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry
Bateman, N. W.; Tarney, C. M.; Abulez, T. S.; Hood, B. L.; Conrads, K. A.; Zhou, M.; Soltis, A. R.; Teng, P.-i.; Jackson, A.; Tian, C.; Dalgard, C. L.; Wilkerson, M. D.; Kessler, M. D.; Shriver, C. D.; Hu, H.; Cote, M.; Parker, G. J.; Segars, J.; Al-Hendy, A.; Risinger, J. R.; Darcy, K. M.; Casablanca, Y.; Maxwell, G. L.; Conrads, T. P.; O'Connor, T. D.
10.1101/2020.11.23.380337 — cancer biology — Posted on 2020-11-24
776 Genotype-free individual genome reconstruction of Multiparental Population Models by RNA sequencing data
Choi, K.; He, H.; Gatti, D. M.; Philip, V. M.; Raghupathy, N.; Gyuricza, I. G.; Munger, S. C.; Chesler, E. J.; Churchill, G. A.
10.1101/2020.10.11.335323 — bioinformatics — Posted on 2020-11-24
779 Transcriptome analysis of an albino mutant in Haworthia cooperi var. pilifera
Ren, M.; Zhang, Y.; Xu, H.; Zhu, Q.; Wang, Z.; Liu, S.; Li, P.; Liang, B.
10.1101/2020.11.24.396358 — genetics — Posted on 2020-11-24
780 Genomic Analyses of New Genes and Their Phenotypic Effects Reveal Rapid Evolution of Essential Functions in Drosophila Development
Xia, S.; VanKuren, N. W.; Chen, C.; Zhang, L.; Kemkemer, C.; Shao, Y.; Jia, H.; Lee, U.; Advani, A. S.; Gschwend, A.; Vibranovski, M.; Chen, S.; Zhang, Y. E.; Long, M.
10.1101/2020.10.27.357848 — evolutionary biology — Posted on 2020-11-24
782 Multispecies integrated population model reveals bottom-up dynamics in a seabird predator-prey system
Queroue, M.; Barbraud, C.; Barraquand, F.; Turek, D.; Delord, K.; Pacoureau, N.; Gimenez, O.
10.1101/2020.06.26.174250 — ecology — Posted on 2020-11-24
785 Structural basis of resistance to lincosamide, streptogramin A, and pleuromutilin antibiotics by ABCF ATPases in Gram-positive pathogens
Crowe-McAuliffe, C.; Murina, V.; Turnbull, K. J.; Kasari, M.; Mohamad, M.; Polte, C.; Takada, H.; Vaitkevicius, K.; Johansson, J.; Ignatova, Z.; Atkinson, G. C.; O'Neill, A. C.; Hauryliuk, V.; Wilson, D. N.
10.1101/2020.11.24.396648 — microbiology — Posted on 2020-11-24
786 Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host
Onguka, O.; Babin, B. M.; Lakemeyer, M.; Foe, I. T.; Amara, N.; Terrell, S. M.; Lum, K. M.; Cieplak, P.; Niphakis, M. J.; Long, J. Z.; Bogyo, M.
10.1101/2020.11.24.396663 — microbiology — Posted on 2020-11-24
790 Glycolic acid protects neurons against ischemia in vitro and in two animal models of stroke
Chovsepian, A.; Berchtold, D.; Winek, K.; Mamrak, U.; Ramirez-Alvarez, I.; Dening, Y.; Weitbrecht, L.; Dames, C.; Aillery, M.; Fernandez-Sanz, C.; Dieterich, M.; Falkai, P.; Plesnila, N.; Meisel, A.; Pan-Montojo, F. J.
10.1101/2020.11.24.396051 — neuroscience — Posted on 2020-11-24
791 Disease specific alterations in the olfactory mucosa of patients with Alzheimer's disease
Lampinen, R.; Fazaludeen, M. F.; Avesani, S.; Ord, T.; Penttila, E.; Lehtola, J.-M.; Saari, T.; Hannonen, S.; Saveleva, L.; Kaartinen, E.; Acosta, F. F.; Cruz-Haces, M.; Lopponen, H.; Mackay-Sim, A.; Malm, T.; Kaikkonen-Maatta, M.; Koivisto, A.; White, A. R.; Giugno, R.; Chew, S.; Kanninen, K. M.
10.1101/2020.11.24.395947 — neuroscience — Posted on 2020-11-24
795 Ovarian carcinosarcoma genomics and pre-clinical models highlight the N-MYC pathway as a key driver and susceptibility to EMT-targeting therapy
Ho, G. Y.; Kyran, E.; Bedo, J.; Wakefield, M.; Ennis, D.; Mirza, H.; Cooke, S.; Lieschke, E.; Vandenberg, C.; Kondrashova, O.; Upstill-Goddard, R.; Bailey, U.-M.; Biankin, S.; Roxburgh, P.; Glasspool, R.; Bryson, G.; Biankin, A.; Ratnayake, G.; McNally, O.; Traficante, N.; DeFazio, A.; Bowtell, D.; McNeish, I.; Papenfuss, A.; Scott, C.; Barker, H.
10.1101/2020.11.24.396796 — cancer biology — Posted on 2020-11-24
796 High-throughput phenotyping methods for quantifying hair fiber morphology
Lasisi, T.; Zaidi, A. A.; Webster, T. H.; Stephens, N. B.; Routch, K.; Jablonski, N. G.; Shriver, M. D.
10.1101/2020.11.24.392191 — bioinformatics — Posted on 2020-11-24
798 Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
Schuller, M.; Correy, G. J.; Gahbauer, S.; Fearon, D.; Wu, T.; Diaz, R. E.; Young, I. D.; Carvalho Martins, L.; Smith, D. H.; Schulze-Gahmen, U.; Owens, T. W.; Deshpande, I.; Merz, G. E.; Thwin, A. C.; Biel, J. T.; Peters, J. K.; Moritz, M.; Herrera, N.; Kratochvil, H. T.; QCRG Structural Biology Consortium, ; Aimon, A.; Bennett, J. M.; Brandao Neto, J.; Cohen, A. E.; Dias, A.; Douangamath, A.; Dunnett, L.; Fedorov, O.; Ferla, M. P.; Fuchs, M.; Gorrie-Stone, T. J.; Holton, J. M.; Johnson, M. G.; Krojer, T.; Meigs, G.; Powell, A. J.; Rack, J. G. M.; Rangel, V. L.; Russi, S.; Skyner, R. E.; Smi
10.1101/2020.11.24.393405 — biochemistry — Posted on 2020-11-24
800 Copy number signatures predict chromothripsis and associate with poor clinical outcomes in patients with newly diagnosed multiple myeloma
Maclachlan, K.; Rustad, E. H.; Derkach, A.; Zheng-Lin, B.; Yellapantula, V.; Diamond, B.; Hultcrantz, M.; Ziccheddu, B.; Boyle, E.; Blaney, P.; Bolli, N.; Zhang, Y.; Dogan, A.; Lesohkin, A.; Morgan, G.; Landgren, O.; Maura, F.
10.1101/2020.11.24.395939 — genomics — Posted on 2020-11-24
805 Cassette recruitment in the chromosomal Integron of Vibrio cholerae
Vit, C.; Richard, E.; Fournes, F.; Whiteway, C.; Eyer, X.; Lapaillerie, D.; Parissi, V.; Mazel, D.; Loot, C.
10.1101/2020.11.24.395434 — molecular biology — Posted on 2020-11-24
806 The ESCRT-III machinery participates in the production of extracellular vesicles and protein export during Plasmodium falciparum infection
Avalos-Padilla, Y.; Georgiev, V. N.; Lantero, E.; Pujals, S.; Verhoef, R.; Borgheti-Cardoso, L. N.; Albertazzi, L.; Dimova, R.; Fernandez-Busquets, X.
10.1101/2020.11.24.395756 — microbiology — Posted on 2020-11-24
807 Robust expression of LINE-1 retrotransposon encoded proteins in oral squamous cell carcinoma
Mukherjee, K.; Sur, D.; Singh, A.; Rai, S.; Das, N. S.; Narindi, S.; Sekar, R.; Dhingra, V. K.; Jat, B.; Balraam, K. V. V.; Agarwal, S. P.; Mandal, P. K.
10.1101/2020.11.24.395285 — cancer biology — Posted on 2020-11-24
808 Entropy-driven translocation of disordered proteins through the Gram-positive bacterial cell wall
Halladin, D. K.; Ortega, F. E.; Ng, K. M.; Footer, M. J.; Mitic, N. S.; Malkov, S. N.; Gopinathan, A.; Huang, K. C.; Theriot, J. A.
10.1101/2020.11.24.396366 — biophysics — Posted on 2020-11-24
809 EoRNA, a barley gene and transcript abundance database.
Milne, L.; Bayer, M.; Rapazote-Flores, P.; Mayer, C.-D.; Waugh, R.; Simpson, C. G.
10.1101/2020.11.24.395749 — genomics — Posted on 2020-11-24
810 Heterochiasmy facilitated the establishment of gsdf as a novel sex determining gene in Atlantic halibut
Edvardsen, R. B.; Wallerman, O.; Furmanek, T.; Kleppe, L.; Jern, P.; Wallberg, A.; Kjaerner-Semb, E.; Maehle, S.; Olausson, S. K.; Sundstrom, E.; Harboe, T.; Mangor-Jensen, R.; Mogster, M.; Perrichon, P.; Norberg, B.; Rubin, C.-J.
10.1101/2020.11.24.396218 — genomics — Posted on 2020-11-24
811 Genomic evidence supports the introgression between two sympatric stickleback species inhabiting the White Sea basin
Nedoluzhko, A.; Sharko, F.; Tsygankova, S.; Boulygina, E.; Ibragimova, A.; Teslyuk, A.; Galindo-Villegas, J.; Rastorguev, S.
10.1101/2020.11.24.396010 — genomics — Posted on 2020-11-24
812 Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn's disease
Toyonaga, T.; Araba, K. C.; Kennedy, M. M.; Keith, B. P.; Wolber, E. A.; Beasley, C.; Steinbach, E. C.; Schaner, M. R.; Jain, A.; Long, M. D.; Barnes, E. L.; Herfarth, H. H.; Isaacs, K. L.; Hansen, J. J.; Kapadia, M.; Guillem, J. G.; Koruda, M. J.; Rahbar, R.; Sadiq, T.; Sethupathy, P.; Furey, T.; Ehre, C.; Sheikh, S.
10.1101/2020.11.24.396382 — genomics — Posted on 2020-11-24
813 First results on diversity patterns and selective sweeps in a Southeast European panel of maize inbred lines as combined with two West European panels
Galic, V.; Anđelkovic, V.; Kravic, N.; Grcic, N.; Ledencan, T.; Jambrovic, A.; Zdunic, Z.; Nicolas, S. D.; Charcosset, A.; Satovic, Z.; Simic, D.
10.1101/2020.11.24.376087 — genetics — Posted on 2020-11-24
814 Diverse natural variants suppress mutations in hundreds of essential genes
Parts, L.; Batte, A.; Lopes, M.; Yuen, M. W.; Laver, M.; San Luis, B.-J.; Yue, J.-X.; Pons, C.; Eray, E.; Aloy, P.; Liti, G.; van Leeuwen, J.
10.1101/2020.11.24.395855 — genetics — Posted on 2020-11-24
817 Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
Brockdorff, N.; Rodermund, L.; Coker, H.; Oldenkamp, R.; Wei, G.; Bowness, J.; Rajkumar, B.; Nesterova, T. B.; Pinto, D.; Schermelleh, L.
10.1101/2020.11.24.396473 — developmental biology — Posted on 2020-11-24
819 Genetic dissection of the mitochondrial lipoylation pathway in yeast
Pietikainen, L. P.; Rahman, M. T.; Hiltunen, J. K.; Dieckmann, C. L.; Kastaniotis, A. J.
10.1101/2020.11.24.395780 — molecular biology — Posted on 2020-11-24
821 Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound
Zacharopoulou, P.; Marchi, E.; Ogbe, A.; Robinson, N.; Brown, H.; Jones, M.; Parolini, L.; Pace, M.; Grayson, N.; Kaleebu, P.; Rees, H.; Fidler, S.; Goulder, P.; Klenerman, P.; Frater, J.
10.1101/2020.11.24.395574 — microbiology — Posted on 2020-11-24
824 Competition-based screening secures the evolutionary stability of a defensive microbiome
Worsley, S. F.; Innocent, T. M.; Holmes, N. A.; Al-Bassam, M. M.; Wilkinson, B.; Murrell, J. C.; Boomsma, J. J.; Yu, D. W.; Hutchings, M. I.
10.1101/2020.11.24.395384 — evolutionary biology — Posted on 2020-11-24
827 Stable neutralizing antibody levels six months after mild and severe COVID-19 episode
Pradenas, E.; Trinite, B.; Urrea, V.; Marfil, S.; Avila-Nieto, C.; Rodriguez de la Concepcion, M. L.; Tarres-Freixas, F.; Perez-Yanes, S.; Rovirosa, C.; Ainsua-Enrich, E.; Rodon, J.; Vergara-Alert, J.; Sagales, J.; Guallar, V.; Valencia, A.; Izquierdo-Useros, N.; Paredes, R.; Mateu, L.; Chamorro, A.; Massanella, M.; Carrillo, J.; Clotet, B.; Blanco, J.
10.1101/2020.11.22.389056 — immunology — Posted on 2020-11-24
828 Frequency-dependent interactions determine outcome of competition between two breast cancer cell lines
Freischel, A. R.; Damaghi, M.; Cunningham, J. J.; Ibrahim-Hashim, A.; Gillies, R. J.; Gatenby, R. A.; Brown, J. S.
10.1101/2020.03.06.979518 — cancer biology — Posted on 2020-11-24
830 SEPIA: Simulation-based Evaluation of Prioritization Algorithms
Almaraz, K.; Jang, T.; Lewis, M.; Ngo, T.; Song, M.; Moshiri, N.
10.1101/2020.11.23.394890 — bioinformatics — Posted on 2020-11-24
832 Mutations in SARS-CoV-2 spike protein and RNA polymerase complex are associated with COVID-19 mortality risk
Hahn, G.; Wu, C. M.; Lee, S.; Hecker, J.; Lutz, S. M.; Haneuse, S.; Qiao, D.; Cho, M. H.; Randolph, A.; Laird, N. M.; Weiss, S. T.; Silverman, E. K.; Ribbeck, K.; Lange, C.
10.1101/2020.11.17.386714 — genomics — Posted on 2020-11-24
833 Quench me if you can: Alpha-2-macroglobulin trypsin complexes enable serum biomarker analysis by MALDI mass spectrometry
Taraskin, A.; Semenov, K.; Protasov, A.; Lozhkov, A.; Tyulin, A.; Shaldzhyan, A.; Ramsay, E.; Mirgorodskaya, O.; Klotchenko, S.; Zabrodskaya, Y.
10.1101/2020.11.23.394759 — molecular biology — Posted on 2020-11-24
834 The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo
Gruenweller, A.; Mueller, C.; Obermann, W.; Karl, N.; Wendel, H. G.; Taroncher-Oldenburg, G.; Pleschka, S.; Hartmann, R. K.; Ziebuhr, J.
10.1101/2020.11.24.389627 — molecular biology — Posted on 2020-11-24
836 Collateral Sensitivity Associated with Antibiotic Resistance Plasmids
Herencias, C.; Rodriguez-Beltran, J.; Leon-Sampedro, R.; Alonso-del Valle, A.; Palkovicova, J.; Canton, R.; San Millan, A.
10.1101/2020.07.10.198259 — microbiology — Posted on 2020-11-24
837 Insecticide resistance status of Aedes aegypti in Bangladesh
Al-Amin, H. M.; Johora, F. T.; Irish, S. R.; Hossainey, M. R. H.; Vizcaino, L.; Paul, K. K.; Khan, W. A.; Haque, R.; Alam, M. S.; Lenhart, A.
10.1101/2020.07.31.231076 — microbiology — Posted on 2020-11-24
838 A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
Cheng, M. H.; Porritt, R. A.; Noval Rivas, M.; Krieger, J.; Ozdemir, A. B.; Garcia, G.; Arumugaswami, V.; Fries, B. C.; Arditi, M.; Bahar, I.
10.1101/2020.11.24.395079 — immunology — Posted on 2020-11-24
839 Locus coeruleus MRI contrast is associated with cortical thickness in older adults
Bachman, S. L.; Dahl, M. J.; Werkle-Bergner, M.; Duezel, S.; Forlim, C. G.; Lindenberger, U.; Kuehn, S.; Mather, M.
10.1101/2020.03.14.991596 — neuroscience — Posted on 2020-11-24
845 Timing the SARS-CoV-2 Index Case in Hubei Province
Pekar, J.; Worobey, M.; Moshiri, N.; Scheffler, K.; Wertheim, J. O.
10.1101/2020.11.20.392126 — evolutionary biology — Posted on 2020-11-24
846 Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma
Prummel, K. D.; Crowell, H. L.; Nieuwenhuize, S.; Brombacher, E. C.; Daetwyler, S.; Soneson, C.; Kresoja-Rakic, J.; Ronner, M.; Kocere, A.; Ernst, A.; Labbaf, Z.; Clouthier, D. E.; Firulli, A. B.; Sanchez-Iranzo, H.; O'Rourke, R.; Raz, E.; Mercader, N.; Burger, A.; Felley-Bosco, E.; Huisken, J.; Robinson, M. D.; Mosimann, C.
10.1101/2020.11.11.355693 — developmental biology — Posted on 2020-11-24
850 Nucleotide-resolution bacterial pan-genomics with reference graphs
Colquhoun, R. M.; Hall, M. B.; Lima, L.; Roberts, L. W.; Malone, K. M.; Hunt, M.; Letcher, B.; Hawkey, J.; George, S.; Pankhurst, L.; Iqbal, Z.
10.1101/2020.11.12.380378 — bioinformatics — Posted on 2020-11-24
854 Rapidly self-sterilizing PPE capable of 99% SARS-CoV-2 deactivation in 30seconds
Zinn, A. A.; Izadjoo, M.; Kim, H.; Kehn-Hall, K.; Lehman, C.; Brody, R. L.; Roth, R. R.; Vega, A.; Nguyen, K. K.; Ngo, N. T.; Zinn, H. T.; Panny, L.; Flor, R.; Antonopoulos, N.; Stoltenberg, R. M.
10.1101/2020.11.16.384040 — immunology — Posted on 2020-11-24
855 Extensive functional repertoire underpins complex behaviours: insights from Parkinson's disease
Sorrentino, P.; Rucco, R.; Baselice, F.; De Micco, R.; Tessitore, A.; Hillebrand, A.; Mandolesi, L.; Breakspear, M.; Gollo, L. L.; Sorrentino, G.
10.1101/823849 — neuroscience — Posted on 2020-11-24
856 The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse
Berwian, I. M.; Wenzel, J. G.; Kuehn, L.; Schnuerer, I.; Kasper, L.; Veer, I. M.; Seifritz, E.; Stephan, K. E.; Walter, H.; Huys, Q. J. M.
10.1101/2020.02.06.937268 — neuroscience — Posted on 2020-11-24
858 Design of a Companion Bioinformatic Tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants
Massacci, A.; Sperandio, E.; D'Ambrosio, L.; Maffei, M.; Palombo, F.; Aurisicchio, L.; Ciliberto, G.; Pallocca, M.
10.1101/2020.06.22.133355 — bioinformatics — Posted on 2020-11-24
860 The methylomes of Lake Malawi cichlids reveal epigenetic variation associated with phenotypic diversification
Vernaz, G.; Malinsky, M.; Svardal, H.; Du, M.; Tyers, A. M.; Santos, M. E.; Durbin, R.; Genner, M. J.; Turner, G. F.; Miska, E. A.
10.1101/2020.11.24.383034 — evolutionary biology — Posted on 2020-11-24
865 Identifying genetic variants associated with cerebellar volume in 33,265 individuals from the UK-Biobank
Chambers, T.; Escott-Price, V.; Legge, S. E.; Baker, E.; Singh, K. D.; Walters, J. T.; Caseras, X.; Anney, R. J.
10.1101/2020.11.24.393249 — neuroscience — Posted on 2020-11-24
866 Memory Transfer of Random Time Patterns Across Modalities
Kang, H.; Auksztulewicz, R.; Chan, C. H.; Cappotto, D.; Rajendran, V. G.; Schnupp, J. W. H.
10.1101/2020.11.24.395368 — neuroscience — Posted on 2020-11-24
867 Lithium inhibits tryptophan catabolism via the inflammation-induced kynurenine pathway in human microglia
Goettert, R.; Fidzinski, P.; Kraus, L.; Schneider, U. C.; Holtkamp, M.; Endres, M.; Gertz, K.; Kronenberg, G.
10.1101/2020.11.24.388470 — neuroscience — Posted on 2020-11-24
869 The role of SOX9 in non-small cell lung cancer progression is histopathology-selective.
Verschuren, E. W.; Bao, J.; Närhi, K.; Teodosio, A.; Hemmes, A.; Linnavirta, N. M.; Mäyränpää, M. I.; Salmenkivi, K.; Le Quesne, J.
10.1101/2020.11.23.393926 — cancer biology — Posted on 2020-11-24
874 Reproducible abnormalities of functional gradient reliably predict clinical and cognitive symptoms in schizophrenia
Wang, M.; Li, A.; Liu, Y.; Yan, H.; Sun, Y.; Song, M.; Chen, J.; Chen, Y.; Wang, H.; Guo, H.; Wan, P.; Lv, L.; Yang, Y.; Li, P.; Lu, L.; Yan, J.; Wang, H.; Zhang, H.; Zhang, D.; Jiang, T.; Liu, B.
10.1101/2020.11.24.395251 — neuroscience — Posted on 2020-11-24
879 A comprehensive analysis of vomeronasal organ transcriptome reveals variable gene expression depending on age and function in rabbits
R Villamayor, P.; Robledo, D.; Fernandez, C.; Gullon, J.; Quintela, L.; Sanchez-Quinteiro, P.; Martinez, P.
10.1101/2020.11.24.395517 — genomics — Posted on 2020-11-24
880 Establishment of a highly efficient gene disruption strategy to analyze and manipulate lipid co-regulatory networks
Harayama, T.; Hashidate-Yoshida, T.; Aguilera-Romero, A.; Hamano, F.; Morimoto, R.; Shimizu, T.; Riezman, H.
10.1101/2020.11.24.395632 — genetics — Posted on 2020-11-24
881 CloneSeq: A Highly Sensitive Single-cell Analysis Platform for Comprehensive Characterization of Cells from 3D Culture
Bavli, D.; Sun, X.; Kozulin, C.; Ennis, D.; Motzik, A.; Biran, A.; Brielle, S.; Alajem, A.; Meshorer, E.; Buxboim, A.; Ram, O.
10.1101/2020.11.24.395541 — molecular biology — Posted on 2020-11-24
884 Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles forcholesterol delivery in Huntington disease
Birolini, G.; Valenza, M.; Ottonelli, I.; Passoni, A.; Favagrossa, M.; Duskey, J. T.; Bombaci, M.; Vandelli, M. A.; Colombo, L.; Bagnati, R.; Caccia, C.; Leoni, V.; Taroni, F.; Forni, F.; Ruozi, B.; Salmona, M.; Tosi, G.; Cattaneo, E.
10.1101/2020.11.24.395525 — neuroscience — Posted on 2020-11-24
885 MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
Takado, Y.; Takuwa, H.; Sampei, K.; Urushihata, T.; Takahashi, M.; Shimojo, M.; Uchida, S.; Nitta, N.; Shibata, S.; Nagashima, K.; Ochi, Y.; Ono, M.; Maeda, J.; Tomita, Y.; Sahara, N.; Near, J.; Aoki, I.; Shibata, K.; Higuchi, M.
10.1101/2020.10.25.353888 — neuroscience — Posted on 2020-11-24
887 The Physcomitrium (Physcomitrella) patens PpKAI2L receptors for strigolactones and related compounds highlight MAX2 dependent and independent pathways
LOPEZ-OBANDO, M.; GUILLORY, A.; BOYER, F.-D.; CORNU, D.; HOFFMANN, B.; LE BRIS, P.; POUVREAU, J.-B.; DELAVAULT, P.; RAMEAU, C.; DE SAINT GERMAIN, A.; BONHOMME, S.
10.1101/2020.11.24.395954 — plant biology — Posted on 2020-11-24
889 Crystal structure of prototype foamy virus (PFV) protease-reverse transcriptase fusion (PR-RT) reveals conformational plasticity: implications for function
Harrison, J. J. E. K.; Tuske, S.; Das, K.; Ruiz, F. X.; Bauman, J. D.; Boyer, P.; DeStefano, J. J.; Hughes, S. H.; Arnold, E.
10.1101/2020.11.23.395087 — biophysics — Posted on 2020-11-24
891 Critical Assessment of Protein Intrinsic Disorder Prediction
Necci, M.; Piovesan, D.; CAID Predictors, ; DisProt Curators, ; Tosatto, S. C. E.
10.1101/2020.08.11.245852 — bioinformatics — Posted on 2020-11-24
893 Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Edwards, R. J.; Field, M. A. J.; Ferguson, J. M.; Dudchenko, O.; Keilwagen, J.; Rosen, B. D.; Johnson, G. S.; Rice, E. S.; Hillier, L.; Hammond, J. M.; Tomwarnicki, S. G.; Omer, A.; Skvortsova, K.; Bogdanovic, O.; Zammit, R. A.; Aiden, E. L.; Warren, W. C.; Ballard, J. W. O.
10.1101/2020.11.11.379073 — genomics — Posted on 2020-11-24
894 Clonal dynamics in early human embryogenesis inferred from somatic mutation
Park, S.; Mali, N. M.; Kim, R.; Choi, J.-W.; Lee, J.; Lim, J.; Park, J. M.; Park, J. W.; Kim, D.; Kim, T.; Yi, K.; Choi, J. H.; Kwon, S. G.; Hong, J. H.; Youk, J.; An, Y.; Kim, S. Y.; Kim, M.; Kim, D. S.; Park, J. Y.; Oh, J. W.; Ju, Y. S.
10.1101/2020.11.23.395244 — genomics — Posted on 2020-11-24
897 The anti-inflammatory peptide Catestatin blocks chemotaxis
Muntjewerff, E. M.; Parv, K.; Mahata, S. K.; Phillipson, M.; Christoffersson, G.; van den Bogaart, G.
10.1101/2020.11.23.393934 — cell biology — Posted on 2020-11-24
900 Rapid shift in microbial community structure in a neutral hydrothermal hot spring from Costa Rica
Rojas-Gätjens, D.; Arce-Rodriguez, A.; Puente-Sanchez, F.; Avendano, R.; Libby, E.; Conejo-Barboza, G.; Mora-Amador, R.; Rojas-Jimenez, K.; Pieper, D. H.; Chavarria, M.
10.1101/2020.11.23.395137 — microbiology — Posted on 2020-11-24
902 The SC-SNc pathway boosts appetitive locomotion in predatory hunting
Huang, M.; Li, D.; Pei, Q.; Xie, z.; Gu, H.; Liu, A.; Chen, Z.; Wang, Y.; Sun, F.; Li, Y.; Zhang, J.; He, M.; Xie, Y.; Zhang, F.; Qi, X.; Shang, C.; Cao, P.
10.1101/2020.11.23.395004 — neuroscience — Posted on 2020-11-24
903 Predicting perturbation effects from resting state activity using functional causal flow
Nejatbakhsh, A.; Fumarola, F.; Esteki, S.; Toyoizumi, T.; Kiani, R.; Mazzucato, L.
10.1101/2020.11.23.394916 — neuroscience — Posted on 2020-11-24
908 PCK2 opposes mitochondrial respiration and maintains the redox balance in starved lung cancer cells
Leithner, K.; Grasmann, G.; Planque, M.; Madreiter-Sokolowski, C. T.; Hrzenjak, A.; Graier, W. F.; Fendt, S.-M.; Olschewski, H.
10.1101/2020.11.23.393686 — cancer biology — Posted on 2020-11-24
913 Visuomotor Activation of Inhibition-Processing in Pediatric Obsessive Compulsive Disorder: A Magnetoencephalography Study
Nishat, E.; Dockstader, C.; Wheeler, A. L.; Tan, T.; Anderson, J. A.; Mendlowitz, S.; Mabbott, D. J.; Arnold, P. D.; Ameis, S. H.
10.1101/2020.11.23.394841 — neuroscience — Posted on 2020-11-24
915 Membrane-tethered peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as allosteric biased ligands
Nassour, H.; Hoang, T. A.; Martin, R. D.; Dallagnol, J. C. C.; Billard, E.; Letourneau, M.; Novellino, E.; Carotenuto, A.; Allen, B. G.; Tanny, J. C.; Fournier, A.; Hebert, T. E.; Chatenet, D.
10.1101/2020.11.23.394270 — pharmacology and toxicology — Posted on 2020-11-24
918 Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone
Whitworth, L.; Troll, R.; Pagan, A. J.; Roca, F.; Edelstein, P. H.; Troll, M.; Tobin, D.; Phu, N. H.; Bang, N. D.; Thwaites, G.; Thuong Thuong, N. T.; Sewell, R.; Ramakrishnan, L.
10.1101/2020.11.23.394437 — immunology — Posted on 2020-11-24
919 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-11-24
921 Importin α2 association with chromatin: Direct DNA binding via a novel DNA binding domain
Jibiki, K.; Kodama, T.; Suenaga, A.; Kawase, Y.; Shibazaki, N.; Nomoto, S.; Nagasawa, S.; Nagashima, M.; Shimodan, S.; Kikuchi, R.; Okayasu, M.; Takashita, R.; Mehmood, R.; Saitoh, N.; Yoneda, Y.; Akagi, K.-i.; Yasuhara, N.
10.1101/2020.05.04.075580 — molecular biology — Posted on 2020-11-24
922 LayNii: A software suite for layer-fMRI. revision 1
Huber, L.; Poser, B. A.; Bandettini, P. A.; Arora, K.; Wagstyl, K.; Cho, S.; Goense, J.; Nothnagel, N.; Morgan, A. T.; Mueller, A. K.; van den Hurk, J.; Reynolds, R. C.; Glen, D. R.; Goebel, R. W.; Gulban, O. F.
10.1101/2020.06.12.148080 — neuroscience — Posted on 2020-11-24
924 Filtering Variables for Supervised Sparse Network Analysis
Towle-Miller, L. M.; Miecznikowski, J. C.; Zhang, F.; Tritchler, D. L.
10.1101/2020.03.12.985077 — bioinformatics — Posted on 2020-11-24
925 CBX1 variants cause a neurodevelopmental syndrome due to facultative heterochromatin dysfunction
Iwata-Otsubo, A.; Dias, K.-R.; Su, C.; Lindsay-Temple, S.; Zhu, Y.; Fiordaliso, S.; Ritter, A.; Baker, S. W.; Kuroda, Y.; Keena, B. A.; Grant, S. F.; Musuwadi Subramanian, G.; Zackai, E.; Edwards, M.; Evans, C.-A.; Dulik, M. C.; Buckley, M. F.; Roscioli, T.; Izumi, K.
10.1101/2020.09.29.319228 — genetics — Posted on 2020-11-24
926 Suboptimal intermediates underlie evolution of the Bicoid homeodomain
Onal, P.; Gunasinghe, H. I.; Umezawa, K. Y.; Zheng, M.; Ling, J.; Azeez, L.; Dalmeus, A.; Tazin, T.; Small, S.
10.1101/2020.08.20.257824 — evolutionary biology — Posted on 2020-11-24
934 MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
Takado, Y.; Takuwa, H.; Sampei, K.; Urushihata, T.; Takahashi, M.; Shimojo, M.; Uchida, S.; Nitta, N.; Shibata, S.; Nagashima, K.; Ochi, Y.; Ono, M.; Maeda, J.; Tomita, Y.; Sahara, N.; Near, J.; Aoki, I.; Shibata, K.; Higuchi, M.
10.1101/2020.10.25.353888 — neuroscience — Posted on 2020-11-24
935 Two Parallel Pathways Mediate Olfactory-Driven Backward Locomotion
Israel, S.; Rozenfeld, E.; Weber, D.; Huetteroth, W.; Parnas, M.
10.1101/2020.11.23.393819 — neuroscience — Posted on 2020-11-24
937 Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance
Cintas, C.; Douche, T.; Dantes, Z.; Mouton-Barbosa, E.; Bousquet, M.-P.; Therville, N.; Pont, F.; Cayron, C.; Ramos-Delgado, F.; Thibault, B.; Garmy-Susini, B.; Cappello, P.; Burlet-Schiltz, O.; Hirsch, E.; Gomez-Brouchet, A.; Reichert, M.; Guillermet-Guibert, J.
10.1101/2020.10.08.313833 — cancer biology — Posted on 2020-11-24
938 Analysis of Biological Noise in an Organelle Size Control System
Bauer, D.; Ishikawa, H.; Wemmer, K.; Kondev, J.; Marshall, W. F.
10.1101/2020.08.31.276428 — biophysics — Posted on 2020-11-24
939 Statistical Integration of Two Omics Datasets Using GO2PLS
Gu, Z.; el Bouhaddani, S.; Pei, J.; Houwing-Duistermaat, J.; Uh, H.-W.
10.1101/2020.08.31.274175 — bioinformatics — Posted on 2020-11-24
945 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-11-24
947 (p)ppGpp/GTP and malonyl-CoA modulate Staphylococcus aureus adaptation to FASII antibiotics and provide a basis for synergistic bi-therapy
Pathania, A.; Anba-Mondoloni, J.; Gominet, M.; Halpern, D.; Dairou, J.; Dupont, L.; Lamberet, G.; Trieu-Cuot, P.; Gloux, K.; Gruss, A.
10.1101/2020.03.26.007567 — microbiology — Posted on 2020-11-24
948 Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed
Shibata, T.; Shah, S.; Evans, T.; Coleman, H. N.; Lieblong, B. J.; Spencer, H. J.; Quick, C. M.; Sasagawa, T.; Stephens, O. W.; Peterson, E.; Johann, D.; Lu, Y.-C.; Nakagawa, M.
10.1101/2020.11.07.364844 — immunology — Posted on 2020-11-24
949 Maximally selective single cell target for circuit control in epilepsy
Hadjiabadi, D. H.; Lovett-Barron, M.; Raikov, I.; Sparks, F.; Liao, Z.; Baraban, S. C.; Leskovec, J.; Losonczy, A.; Deisseroth, K.; Soltesz, I.
10.1101/2020.10.20.340364 — neuroscience — Posted on 2020-11-24
957 Evolutionary genetic integration of behavioural and endocrine components of the stress response
Houslay, T. M.; Earley, R. L.; White, S. J.; Lammers, W.; Grimmer, A. J.; Travers, L.; Johnson, E.; Young, A. J.; Wilson, A. J.
10.1101/770586 — evolutionary biology — Posted on 2020-11-23
958 Comparing statistical and mechanistic models to identify the drivers of mortality within a rear-edge beech population
Petit-Cailleux, C.; Davi, H.; Lefevre, F.; Garrigue, J.; Magdalou, J.-A.; Hurson, C.; Magnanou, E.; Muratorio, S.
10.1101/645747 — ecology — Posted on 2020-11-23
962 The mixed genetic origin of the first farmers of Europe
Marchi, N.; Winkelbach, L.; Schulz, I.; Brami, M.; Hofmanova, Z.; Blocher, J.; Reyna-Blanco, C. S.; Diekmann, Y.; Thiery, A.; Kapopoulou, A.; Link, V.; Piuz, V.; Kreutzer, S.; Figarska, S. M.; Ganiatsou, E.; Pukaj, A.; Karul, N.; Gerritsen, F.; Pechtl, J.; Peters, J.; Zeeb-Lanz, A.; Lenneis, E.; Teschler-Nicola, M.; Triantaphyllou, S.; Stefanovi, S.; Papageorgopoulou, C.; Wegmann, D.; Burger, J.; Excoffier, L.
10.1101/2020.11.23.394502 — evolutionary biology — Posted on 2020-11-23
963 Beyond fear centers: a distributed fMRI-based neuromarker for the subjective experience of fear
Zhou, F.; Zhao, W.; Qi, Z.; Geng, Y.; Yao, S.; Kendrick, K. M.; Wager, T. D.; Becker, B.
10.1101/2020.11.23.394973 — neuroscience — Posted on 2020-11-23
964 Peptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry
Bateman, N. W.; Tarney, C.; Abulez, T.; Hood, B. L.; Conrads, K.; Zhou, M.; Soltis, A. R.; Teng, P.-i.; Jackson, A.; Tian, C.; Dalgard, C.; Wilkerson, M.; Kessler, M.; Shriver, C. D.; Hu, H.; Cote, M.; Parker, G. J.; Segars, J.; Al-Hendy, A.; Risinger, J.; Darcy, K.; Casablanca, Y.; George, M. L.; Conrads, T. P.; O'Connor, T. D.
10.1101/2020.11.23.380337 — cancer biology — Posted on 2020-11-23
965 In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1
Chaudhari, A.; Chaudhari, M.; Mahera, S.; Saiyed, Z.; Nathani, N.; Shukla, S.; Patel, C.; Patel, D.; Joshi, M.; Joshi, C.
10.1101/2020.11.22.393009 — bioinformatics — Posted on 2020-11-23
966 find-tfbs: a tool to identify functional non-coding variants associated with complex human traits using open chromatin maps and phased whole-genome sequences
Meric de Bellefon, S.; Thibord, F.; Auer, P. L.; Blangero, J.; Coban-Akdemir, Z. H.; Floyd, J. S.; Fornage, M.; Johnsen, J. M.; Lange, L. A.; Lewis, J. P.; Mathias, R. A.; McHugh, C. P.; Moon, J.-Y.; Reiner, A. P.; Stilp, A. M.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Lettre, G.
10.1101/2020.11.23.394296 — genomics — Posted on 2020-11-23
967 HPRep: Quantifying reproducibility in HiChIP and PLAC-seq datasets
Rosen, J. D.; Yang, Y.; Abnousi, A.; Chen, J.; Song, M.; Jones, I. R.; Shen, Y.; Hu, M.; Li, Y.
10.1101/2020.11.23.394239 — genomics — Posted on 2020-11-23
968 DNA barcodes and reliable molecular identifications in a diverse group of invasive pests: lessons from Bactrocera fruit flies on variation across the COI gene, introgression, and standardization
Doorenweerd, C.; San Jose, M.; Leblanc, L.; Barr, N.; Geib, S.; Chung, A. Y. C.; Dupuis, J.; Ekayanti, A.; Fiegalan, E.; Hemachandra, K. S.; Hossain, M. A.; Huang, C.-L.; Hsu, Y.-F.; Morris, K. Y.; Maryani Mustapeng, A.; Niogret, J.; Hong Pham, T.; Sirisena, U. G. A. I.; Rubinoff, D.
10.1101/2020.11.23.394510 — evolutionary biology — Posted on 2020-11-23
971 Challenges for targeting SARS-CoV-2 proteases as a therapeutic strategy for COVID-19
Steuten, K.; Kim, H.; Widen, J. C.; Babin, B. M.; Onguka, O.; Lovell, S.; Bolgi, O.; Cerikan, B.; Cortese, M.; Muir, R. K.; Bennett, J. M.; Geiss-Friedlander, R.; Peters, C.; Bartenschlager, R.; Bogyo, M.
10.1101/2020.11.21.392753 — microbiology — Posted on 2020-11-23
972 Response to thermal and infection stresses in an American vector of visceral leishmaniasis.
Martins, K. A.; Moraes, C. S.; Broughton, S. J.; Lazzari, C. R.; Bates, P. A.; Pereira, M. H.; Dillon, R. J.
10.1101/2020.11.23.373100 — microbiology — Posted on 2020-11-23
973 Stable neutralizing antibody levels six months after mild and severe COVID-19 episode
Pradenas, E.; Trinite, B.; Urrea, V.; Marfil, S.; Avila-Nieto, C.; Rodriguez de la Concepcion, M. L.; Tarres-Freixas, F.; Perez-Yanes, S.; Rovirosa, C.; Ainsua-Enrich, E.; Rodon, J.; Vergara-Alert, J.; Sagales, J.; Guallar, V.; Valencia, A.; Izquierdo-Useros, N.; Paredes, R.; Mateu, L.; Chamorro, A.; Massanella, M.; Carrillo, J.; Clotet, B.; Blanco, J.
10.1101/2020.11.22.389056 — immunology — Posted on 2020-11-23
975 Neural signatures of predictive language processing in Parkinson's disease with and without mild cognitive impairment
Leon-Cabrera, P.; Pagonabarraga, J.; Moris, J.; Martinez-Horta, S.; Marin-Lahoz, J.; Horta-Barba, A.; Bejr-Kasem, H.; Kulisevsky, J.; Rodriguez-Fornells, A.
10.1101/2020.11.23.392647 — neuroscience — Posted on 2020-11-23
978 A Synthetic Defective Interfering SARS-CoV-2
Yao, S.; Narayanan, A.; Majowicz, S.; Jose, J.; Archetti, M.
10.1101/2020.11.22.393587 — synthetic biology — Posted on 2020-11-23
979 The multidisciplinary nature of COVID-19 research
Arencibia-Jorge, R.; Garcia-Garcia, L.; Galban-Rodriguez, E.; Carrillo-Calvet, H.
10.1101/2020.11.23.394312 — scientific communication and education — Posted on 2020-11-23
980 Obesity-Activated Lung Stomal Cells Promote Myeloid-Lineage Cell Accumulation and Breast Cancer Metastasis
Hillers-Ziemer, L. E.; Williams, A. E.; Janquart, A.; Grogan, C.; Thompson, V.; Sanchez, A.; Arendt, L. M.
10.1101/2020.11.23.394387 — cancer biology — Posted on 2020-11-23
986 A repurposed, blood gene signature is associated with poor outcomes in SARS-CoV-2
Juan-Guardela, B. M.; Sun, J.; Zhang, T.; Xu, B.; Michaud, G.; Herazo-Maya, J. D.
10.1101/2020.11.21.392670 — genomics — Posted on 2020-11-23
989 Quench me if you can: Alpha-2-macroglobulin trypsin complexes enable serum biomarker analysis by MALDI mass spectrometry
Taraskin, A.; Semenov, K.; Protasov, A.; Lozhkov, A.; Tyulin, A.; Shaldzhyan, A.; Ramsay, E.; Mirgorodskaya, O.; Klotchenko, S.; Zabrodskaya, Y.
10.1101/2020.11.23.394759 — molecular biology — Posted on 2020-11-23
991 Enteric glial cells respond to a dietary change in the lamina propria in a MyD88-dependent manner
Liu, Z.; Sun, H.; Liang, M.; Gao, J.; Meng, L.; Zheng, X.; Wei, Y.; Kou, Y.; Wang, Y.
10.1101/2020.11.23.394601 — neuroscience — Posted on 2020-11-23
993 Interactions of anti-COVID-19 drug candidates with multispecific ABC and OATP drug transporters
Telbisz, A.; Ambrus, C.; Mozner, O.; Szabo, E.; Varady, G.; Bakos, E.; Sarkadi, B.; Ozvegy-Laczka, C.
10.1101/2020.11.21.392555 — pharmacology and toxicology — Posted on 2020-11-23
995 Metabolic differentiation of co-occurring Accumulibacter clades revealed through genome-resolved metatranscriptomics
McDaniel, E. A.; Moya-Flores, F.; Keene Beach, N.; Camejo, P. Y.; Oyserman, B. O.; Kizaric, M.; Khor, E. H.; Noguera, D. R.; McMahon, K. D.
10.1101/2020.11.23.394700 — genomics — Posted on 2020-11-23
997 SAICAr-dependent and independent effects of ADSL deficiency on neurodevelopment
Dutto, I.; Gerhards, J.; Herrera, A.; Junza, A.; Yanes, O.; Boeckx, C.; Burkhalter, M. D.; Pons, S.; Philipp, M.; Luders, J.; Stracker, T. H.
10.1101/2020.11.23.394767 — developmental biology — Posted on 2020-11-23
1000 The impact of multifactorial stress combination on plant growth and survival
Zandalinas, S. I.; Sengupta, S.; Fritschi, F. B.; Azad, R.; Nechushtai, R.; Mittler, R.
10.1101/2020.11.23.394593 — plant biology — Posted on 2020-11-23
1001 SCReadCounts: Estimation of cell-level SNVs from scRNA-seq data
Prashant, N.; Alomran, N.; Chen, Y.; Liu, H.; Bousounis, P.; Movassagh, M.; Edwards, N. J.; Horvath, A.
10.1101/2020.11.23.394569 — bioinformatics — Posted on 2020-11-23
1003 Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences.
Zhang, X.; Harding, B.; Aggad, D.; Courtine, D.; Chen, J.-X.; Pujol, N.; Ewbank, J.
10.1101/2020.11.23.391201 — microbiology — Posted on 2020-11-23
1005 Pulmonary B cells ameliorate Alzheimer's disease-like neuropathology
Feng, W.; Zhang, Y.; Wang, T.; Wang, Z.; Chen, Y.; Sheng, C.; Zou, Y.; Pang, Y.; Gao, J.; Zhang, Y.; Shi, J.; Li, Q.; Xiao, M.
10.1101/2020.11.23.393942 — neuroscience — Posted on 2020-11-23
1007 Household-Level Risk Factors for Aedes aegypti Pupal Density in Guayaquil, Ecuador
Ha, T.-A.; Leon, T. M.; Lalangui, K.; Ponce, P.; Marshall, J. M.; Cevallos, V.
10.1101/2020.11.23.391938 — ecology — Posted on 2020-11-23
1009 Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis
Pradhan, S. J.; reddy, p. c.; Smutny, M.; Sharma, A.; Sako, K.; Oak, M. S.; Shah, R.; Pal, M.; Deshpande, O.; Tang, Y.; Mishra, R. K.; Deshpande, G.; Giraldez, A.; Sonawane, M.; Heisenberg, C.-P.; Galande, S.
10.1101/2020.11.23.394171 — developmental biology — Posted on 2020-11-23
1010 Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
Matsuda, S.; Schaefer, J. V.; Mii, Y.; Hori, Y.; Bieli, D.; Taira, M.; Plueckthun, A.; Affolter, M.
10.1101/2020.11.23.394379 — developmental biology — Posted on 2020-11-23
1011 Bone marrow stromal cell transplantation ameliorates cytopenia caused by depletion FAP-α expressing cells.
Camarillo, E.; Watson, L.; Loftus, P.; Alagesan, S.; O'Donoghue, Y.; Deedigan, L. M.; O'Flynn, L.; Barkley, L. R.; Elliman, S. J.
10.1101/2020.11.23.393959 — cell biology — Posted on 2020-11-23
1013 The Drosophila Baramicin polypeptide gene protects against fungal infection
Hanson, M. A.; Cohen, L. B.; Marra, A.; Iatsenko, I.; Wasserman, S. A.; Lemaitre, B.
10.1101/2020.11.23.394148 — immunology — Posted on 2020-11-23
1014 A novel, ataxic mouse model of Ataxia Telangiectasia caused by a clinically relevant nonsense mutation
Perez, H.; Abdallah, M. F.; Chavira, J. I.; Egeland, M. T.; Vo, K. L.; Sanghez, V.; Buechsenschuetz, C. L.; Kim, J. L.; Pind, M.; Nakamura, K.; Hicks, G. G.; Gatti, R. A.; Madrenas, J.; Iacovino, M.; McKinnon, P.; Mathews, P. J.
10.1101/2020.11.23.394098 — neuroscience — Posted on 2020-11-23
1015 Two Parallel Pathways Mediate Olfactory-Driven Backward Locomotion
Israel, S.; Rozenfeld, E.; Weber, D.; Huetteroth, W.; Parnas, M.
10.1101/2020.11.23.393819 — neuroscience — Posted on 2020-11-23
1017 Different RNA profiles in plasma derived small and large extracellular vesicles of Neurodegenerative diseases patients.
Sproviero, D.; Gagliardi, S.; Zucca, S.; Arigoni, M.; Giannini, M.; Garofalo, M.; Olivero, M.; Dell'Orco, M.; Pansarasa, O.; Bernuzzi, S.; Avenali, M.; Cotta Ramusino, M.; Diamanti, L.; Minafra, B.; Perini, G.; Zangaglia, R.; Costa, A.; Ceroni, M.; Perrone-Bizzozero, N. I.; Cereda, C.
10.1101/2020.11.23.390591 — neuroscience — Posted on 2020-11-23
1018 Building a virtual summer research experience in cancer for high school and early undergraduate students: lessons from the COVID-19 pandemic
Corson, T. W.; Hawkins, S. M.; Sanders, E.; Byram, J.; Cruz, L.-A.; Olson, J.; Speidell, E.; Schnabel, R.; Balaji, A.; Ogbeide, O.; Dinh, J.; Hinshaw, A.; Cummings, L.; Bonds, V.; Nakshatri, H.
10.1101/2020.11.23.393967 — scientific communication and education — Posted on 2020-11-23
1019 Local brassinosteroid biosynthesis enables optimal root growth
Vukasinovic, N.; Wang, Y.; Vanhoutte, I.; Fendrych, M.; Guo, B.; Kvasnica, M.; Jiroutova, P.; Oklestkova, J.; Strnad, M.; Russinova, E.
10.1101/2020.11.23.391474 — plant biology — Posted on 2020-11-23
1021 Cocaine receptor identified as BASP1
Harraz, M. M.; Malla, A. P.; Semenza, E. R.; Shishikura, M.; Hwang, Y.; Kang, I. G.; Song, Y. J.; Snowman, A. M.; Cortes, P.; Snyder, S. H.
10.1101/2020.11.23.392787 — pharmacology and toxicology — Posted on 2020-11-23
1025 Cross-validation of distance measurements in proteins by PELDOR/DEER and single-molecule FRET
Peter, M. F.; Gebhardt, C.; Maechtel, R.; Glaenzer, J.; Thomas, G. H.; Cordes, T.; Hageluecken, G.
10.1101/2020.11.23.394080 — biophysics — Posted on 2020-11-23
1027 Maximizing statistical power to detect clinically associated cell states with scPOST
Millard, N.; Korsunsky, I.; Weinand, K.; Fonseka, C. Y.; Nathan, A.; Kang, J. B.; Raychaudhuri, S.
10.1101/2020.11.23.390682 — bioinformatics — Posted on 2020-11-23
1031 Fine-scale population structure reveals high genetic heterogeneity of the Kuwaiti population in the Arabian Peninsula
Eaaswarkhanth, M.; Pathak, A. K.; Ongaro, L.; Montinaro, F.; Hebbar, P.; Alsmadi, O.; Metspalu, M.; Al-Mulla, F.; Thangavel, A. T.
10.1101/2020.11.23.393892 — genomics — Posted on 2020-11-23
1032 The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II atpro-differentiation genes
Garipler, G.; Lu, C.; Morrissey, A.; Lopez-Zepeda, L. S.; Vidal, S. E.; Aydin, B.; Stadtfeld, M.; Ohler, U.; Mahony, S.; Sanjana, N. E.; Mazzoni, E. O.
10.1101/2020.11.23.391771 — developmental biology — Posted on 2020-11-23
1033 Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns
Chhipi Shrestha, J. K.; Schneider-Poetsch, T.; Suzuki, T.; Mito, M.; Khan, K.; Dohmae, N.; Iwasaki, S.; Yoshida, M.
10.1101/2020.11.23.393835 — molecular biology — Posted on 2020-11-23
1034 Vaccine-induced, but not natural immunity, against the Streptococcal Inhibitor of Complement protects against invasive disease
Tan, L. K. K.; Reglinski, M.; Teo, D.; Reza, N.; Lamb, L. E. M.; Nageshwaran, V.; Turner, C. E.; Wikstroem, M.; Frick, I.-M.; Bjorck, L.; Sriskandan, S.
10.1101/2020.11.22.393389 — microbiology — Posted on 2020-11-23
1035 Verticillium dahliae inoculation and in vitro propagation modify the xylem microbiome and the resistance to Verticillium wilt of a wild olive genotype
ANGUITA-MAESO, M.; TRAPERO-CASAS, J. L.; OLIVARES-GARCIA, C.; Ruano-Rosa, D.; PALOMO-RIOS, E.; JIMENEZ-DIAZ, R. M.; NAVAS-CORTES, J. A.; LANDA, B. B.
10.1101/2020.11.23.392977 — microbiology — Posted on 2020-11-23
1036 A Novel Tool for the Removal of Muscle Artefacts from EEG: Improving Data Quality in the Gamma Frequency Range
Liebisch, A. P.; Eggert, T.; Shindy, A.; Valentini, E.; Irving, S.; Stankewitz, A.; Schulz, E.
10.1101/2020.11.23.393702 — neuroscience — Posted on 2020-11-23
1038 Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy
Masala, N.; Pofahl, M.; Haubrich, A. N.; Nikbakht, N.; Bohmbach, K.; Henneberger, C.; Golcuk, K.; Kelly, T.; Beck, H.
10.1101/2020.11.23.393694 — neuroscience — Posted on 2020-11-23
1039 SREBP2 delivery to striatal astrocytes normalizes transcription of cholesterol biosynthesis genes and ameliorates pathological features in Huntington's disease
Birolini, G.; Verlengia, G.; Talpo, F.; Maniezzi, C.; Zentilin, L.; Giacca, M.; Conforti, P.; Cordiglieri, C.; Caccia, C.; Leoni, V.; Taroni, F.; Biella, G.; Simonato, M.; Cattaneo, E.; Valenza, M.
10.1101/2020.11.23.393793 — neuroscience — Posted on 2020-11-23
1040 Diurnal transcript profiling of the diatom Seminavisrobusta reveals adaptations to a benthic lifestyle
Bilcke, G.; Osuna-Cruz, C. M.; Silva, M. S.; Poulsen, N.; D'hondt, S.; Bulankova, P.; Vyverman, W.; De Veylder, L.; Vandepoele, K.
10.1101/2020.11.23.393678 — systems biology — Posted on 2020-11-23
1042 Arabidopsis cell surface LRR immune receptor signaling through the EDS1-PAD4-ADR1 node
Pruitt, R. N.; Zhang, L.; Saile, S. C.; Karelina, D.; Fröhlich, K.; Wan, W.-L.; Rao, S.; Gust, A. A.; Locci, F.; Joosten, M. H. A. J.; Thomma, B. P. H. J.; Zhou, J.-M.; Dangl, J. L.; Weigel, D.; Parker, J. E.; El Kasmi, F.; Nürnberger, T.
10.1101/2020.11.23.391516 — plant biology — Posted on 2020-11-23
1043 Extracellular vesicles as predictors of individual response to exercise training in youth living with obesity
Pierdona, T. M.; Martin, A.; Obi, P. O.; Seif, S.; Bydak, B.; Eadie, A.; Brunt, K.; McGavock, J. M.; Senechal, M.; Saleem, A.
10.1101/2020.11.20.390872 — physiology — Posted on 2020-11-23
1044 Hsp22 is the key sensor and balancer in mitochondrial dynamic associated metabolic reprogramming
Zaiwa, W.; Ying, C.; Xueyi, W.; Wenjing, W.; Ning, T.; Fang, S.; Yafang, T.; Jingxin, M.; Rujia, L.; Tianchan, P.; Yanmei, H.; Quan, Z.; Lili, W.; Liangxian, L.; Xiaoli, W.; Qinghua, L.
10.1101/2020.11.22.393116 — cancer biology — Posted on 2020-11-23
1045 Targeting mitochondrial respiration and the BCL2 family in MYC-associated B-cell lymphoma
Donati, G.; Rava, M.; Filipuzzi, M.; Nicoli, P.; Cassina, L.; Verrecchia, A.; Doni, M.; Rodighiero, S.; Parodi, F.; Boletta, A.; Vellano, C. P.; Marszalek, J. R.; Draetta, G.; Amati, B.
10.1101/2020.11.22.390922 — cancer biology — Posted on 2020-11-23
1049 Conserved codon adaptation in highly expressed genes is associated with higher regularity in mRNA secondary structures
Sterken, M. G.; Wilbers, R. H. P.; Prins, P.; Snoek, B. L.; Giambasu, G. M.; Slootweg, E.; Holterman, M. H. M.; Helder, J.; Kammenga, J. E.; Schots, A.; Bakker, J.; Westerhof, L. B.
10.1101/2020.11.23.393322 — bioinformatics — Posted on 2020-11-23
1050 Milo: differential abundance testing on single-cell data using k-NN graphs
Dann, E.; Henderson, N. C.; Teichmann, S. A.; Morgan, M. D.; Marioni, J. C.
10.1101/2020.11.23.393769 — bioinformatics — Posted on 2020-11-23
1054 Synaptic vesicles dynamics in neocortical epilepsy
Vannini, E.; Restani, L.; Dilillo, M.; McDonnell, L.; Caleo, M.; Marra, V.
10.1101/2020.01.05.895029 — neuroscience — Posted on 2020-11-23
1056 Operation of a TCA cycle subnetwork in the mammalian nucleus
Kafkia, E.; Andres-Pons, A.; Ganter, K.; Seiler, M.; Jouhten, P.; Pereira, F.; Zaugg, J. B.; Lancrin, C.; Beck, M.; Patil, K. R.
10.1101/2020.11.22.393413 — systems biology — Posted on 2020-11-23
1057 Inhibition of SARS-CoV-2 main protease by allosteric drug-binding
Guenther, S.; Reinke, P. Y. A.; Fernandez-Garcia, Y.; Lieske, J.; Lane, T. J.; Ginn, H.; Koua, F.; Ehrt, C.; Ewert, W.; Oberthuer, D.; Yefanov, O.; Meier, S.; Lorenzen, K.; Krichel, B.; Kopicki, J.; Gelisio, L.; Brehm, W.; Dunkel, I.; Seychell, B.; Gieseler, H.; Norton-Baker, B.; Escudero-Perez, B.; Domaracky, M.; Saouane, S.; Tolstikova, A.; White, T.; Haenle, A.; Groessler, M.; Fleckenstein, H.; Trost, F.; Galchenkova, M.; Gevorkov, Y.; Li, C.; Awel, S.; Peck, A.; Barthelmess, M.; Schluenzen, F.; Lourdu, X. P.; Werner, N.; Andaleeb, H.; Ullah, N.; Falke, S.; Srinivasan, V.; Franca, B.; Schwi
10.1101/2020.11.12.378422 — biophysics — Posted on 2020-11-23
1060 Xist-seeded nucleation sites form local concentration gradients of silencing proteins to inactivate the X-chromosome
Markaki, Y.; Chong, J. G.; Luong, C.; Tan, S. Y. X.; Wang, Y.; Jacobson, E. C.; Maestrini, D.; Dror, I.; Mistry, B. A.; Schoeneberg, J.; Banerjee, A.; Guttman, M.; Chou, T.; Plath, K.
10.1101/2020.11.22.393546 — cell biology — Posted on 2020-11-23
1063 ACTN3 genotype influences skeletal muscle mass regulation and response to dexamethasone
Seto, J. T.; Roeszler, K. N.; Meehan, L. R.; Wood, H. D.; Tiong, C.; Bek, L.; Lee, S. F.; Shah, M.; Quinlan, K. G.; Gregorevic, P.; Houweling, P. J.; North, K. N.
10.1101/2020.11.20.392282 — genetics — Posted on 2020-11-23
1064 Suppressing or blocking Fis1 reverses diabetic endothelial dysfunction in human resistance arteries
Karkala, M.; Egner, J. M.; Wang, J.; Harwig, M. C.; Meacham, K. A.; Puppala, V. K.; Hofeld, B. C.; Arnold, L. A.; Trykall, D. Z.; Hill, R. B.; Widlansky, M. E.
10.1101/2020.11.16.385054 — physiology — Posted on 2020-11-23
1065 Rifampicin exposure reveals within-host Mycobacterium tuberculosis diversity in patients with delayed culture conversion
Genestet, C.; Hodille, E.; Barbry, A.; Berland, J.-L.; Hoffmann, J.; Westeel, E.; Bastian, F.; Guichardant, M.; Venner, S.; Lina, G.; Ginevra, C.; Ader, F.; Goutelle, S.; Dumitrescu, O.; on behalf of the Lyon TB study group,
10.1101/2020.05.22.110775 — microbiology — Posted on 2020-11-23
1066 FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division
Whitley, K. D.; Jukes, C.; Tregidgo, N.; Karinou, E.; Almada, P.; Henriques, R. D.; Dekker, C.; Holden, S.
10.1101/2020.07.01.182006 — microbiology — Posted on 2020-11-23
1068 Large-scale transcriptomics to dissect two years of the life of a fungal phytopathogen interacting with its host plant
Gay, E. J.; Soyer, J. L.; Lapalu, N.; Linglin, J.; Fudal, I.; Da Silva, C.; Wincker, P.; Aury, J.-M.; Cruaud, C.; Levrel, A.; Lemoine, J.; Delourme, R.; Rouxel, T.; Balesdent, M.-H.
10.1101/2020.10.13.331520 — pathology — Posted on 2020-11-23
1069 PHERI - Phage Host Exploration pipeline.
Balaz, A.; Kajsik, M.; Budis, J.; Szemes, T.; Turna, J.
10.1101/2020.05.13.093773 — bioinformatics — Posted on 2020-11-23
1072 Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function
Haward, F.; Maslon, M. M.; Yeyati, P. L.; Bellora, N.; Hansen, J. N.; Aitken, S.; Lawson, J.; von Kriegsheim, A.; Wachten, D.; Mill, P.; Adams, I. R.; Caceres, J. F.
10.1101/2020.09.04.263251 — molecular biology — Posted on 2020-11-23
1073 Accurate Genomic Variant Detection in Single Cells with Primary Template-Directed Amplification
Gonzalez-Pena, V.; Natarajan, S.; Xia, Y.; Klein, D.; Carter, R.; Pang, Y.; Shaner, B.; Annu, K.; Putnam, D. K.; Chen, W.; Connelly, J.; Pruett-Miller, S. M.; Chen, X.; Easton, J.; Gawad, C.
10.1101/2020.11.20.391961 — genomics — Posted on 2020-11-23
1075 The APETALA2 transcription factor LsAP2 regulates seed shape in lettuce
Luo, C.; Wang, S.; Ning, K.; Chen, Z.; Wang, Y.; Yang, J.; Qi, M.; Wang, Q.
10.1101/2020.11.05.370684 — plant biology — Posted on 2020-11-23
1076 Thermal Hazards for Honey Bee Queens
McAfee, A.; Chapman, A.; Higo, H.; Underwood, R. M.; Milone, J. P.; Foster, L. J.; Guarna, M. M.; Tarpy, D. R.; Pettis, J. S.
10.1101/627729 — physiology — Posted on 2020-11-23
1078 Trophic cascade driven by behavioural fine-tuning as naive prey rapidly adjust to a novel predator
Jolly, C. J.; Smart, A. S.; Moreen, J.; Webb, J. K.; Gillespie, G. R.; Phillips, B. L.
10.1101/856997 — ecology — Posted on 2020-11-22
1079 Unified neural pathways that gate affective pain and multisensory innate threat signals to the amygdala
Kang, S. J.; Liu, S.; Ye, M.; Kim, D.-I.; Kim, J.-H.; Oh, T. G.; Peng, J.; Evans, R. M.; Lee, K.-F.; Goulding, M.; Han, S.
10.1101/2020.11.17.385104 — neuroscience — Posted on 2020-11-23
1081 GEMC1-MCIDAS transcriptional program regulates multiciliogenesis in the choroid plexus and acts as a barrier to tumorigenesis
Li, Q.; Han, Z.; Singh, N.; Terre, B.; Fame, R. M.; Arif, U.; Page, T. D.; Zahran, T.; Abdeltawab, A.; Huang, Y.; Cao, P.; Wang, J.; Lu, H.; Lidov, H. G. W.; Surendran, K.; Wu, L.; Schuller, U.; Wechsler-Reya, R. J.; Lehtinen, M. K.; Roy, S.; Liu, Z.; Stracker, T. H.; Zhao, H.
10.1101/2020.11.22.393298 — cancer biology — Posted on 2020-11-22
1082 Modulation of implanted aortic scaffold- involvement of ECM and immune proteins
Banerjee, D.; Nayakawde, N. B.; Antony, D.; Deshmukh, M.; Ghosh, S.; Sihlbom, C.; Ul Haq, U.; Olausson, M.
10.1101/2020.11.21.392654 — bioengineering — Posted on 2020-11-22
1085 TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV
Matkovic, R.; Morel, M.; Larrous, P.; Martin, B.; Bejjani, F.; Emiliani, S.; Gallois-Montbrun, S.; Margottin-Goguet, F.
10.1101/2020.11.22.386656 — molecular biology — Posted on 2020-11-22
1086 Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
Lopez-Gonzalez, A.; Panda, R.; Ponce-Alvarez, A.; Zamora, G.; Escrichs, A.; Martial, C.; Thibaut, A.; Gosseries, O.; Kringelbach, M. L.; Annen, J.; Laureys, S.; Deco, G.
10.1101/2020.11.20.391482 — neuroscience — Posted on 2020-11-22
1088 Hippocampal Transcriptome Profiling Reveals Common Disease Pathways in Chronic Hypoperfusion and Ageing
Baik, S.-H.; Selvaraji, S.; Fann, D. Y.; Jo, D.-G.; Herr, D. R.; Lai, M. K. P.; Chen, C. L.-H.; Drummond, G. R.; Lim, K.-L.; Sobey, C. G.; Arumugam, T.
10.1101/2020.11.21.392449 — neuroscience — Posted on 2020-11-22
1089 Constructing spatial perception through self-touch
Cataldo, A.; Dupin, L.; Dempsey-Jones, H.; Gomi, H.; Haggard, P.
10.1101/2020.11.21.392563 — neuroscience — Posted on 2020-11-22
1090 Age-related Changes in Memory for Object and Position-In-Context
Tran, T. T.; Tobin, K. E.; Block, S. H.; Puliyadi, V.; Gallagher, M.; Bakker, A.
10.1101/2020.11.22.393355 — neuroscience — Posted on 2020-11-22
1094 Sex Differences in MRI-Based Metrics of Glioma Invasion and Brain Mechanics
Anderies, B. J.; Yee, S. F.; Jackson, P. R.; Rickertsen, C. R.; Hawkins-Daarud, A. J.; Johnston, S. K.; Clark-Swanson, K. R.; Hoxworth, J. M.; Le, Y.; Zhou, Y.; Pepin, K. M.; Massey, S. C.; Hu, L. S.; Huston, J. R.; Swanson, K. R.
10.1101/2020.11.21.352724 — biophysics — Posted on 2020-11-22
1096 Genome Wide Association Studies on 7 Yield-relatedTraits of 183 Rice Varieties in Bangladesh
Roy, N.; Kabir, A. H.; Zahan, N.; Mouna, S. T.; Chakravarty, S.; Rahman, A. H.; Bayzid, M. S.
10.1101/2020.11.22.393074 — bioinformatics — Posted on 2020-11-22
1097 Inferring the spatial code of cell-cell interactions and communication across a whole animal body
Armingol, E.; Joshi, C. J.; Baghdassarian, H.; Shamie, I.; Ghaddar, A.; Chan, J.; Her, H.-L.; O'Rourke, E. J.; Lewis, N. E.
10.1101/2020.11.22.392217 — bioinformatics — Posted on 2020-11-22
1098 A probabilistic model for indel evolution: differentiating insertions from deletions
Loewenthal, G.; Rapoport, D.; Avram, O.; Moshe, A.; Itzkovitch, A.; Israeli, O.; Azouri, D.; Cartwright, R. A.; Mayrose, I.; Pupko, T.
10.1101/2020.11.22.393108 — bioinformatics — Posted on 2020-11-22
1100 Dietary zinc restriction induces nociceptive pain with reduced inflammation in mice
de Lima, C. K. F.; Sisnande, T.; da Silva, R. V.; da Silva, V. D.; do Amaral, J. J.; Ochs, S. M.; Roedel dos Santos, B. L.; Miranda, A. L. P.; Lima, L. M. T. d. R.
10.1101/2020.11.21.392548 — biochemistry — Posted on 2020-11-22
1101 From qualitative to quantitative insect metabarcoding: an in tandem multilocus mosquito identification methodology
Kassela, K.; Kouvela, A.; De Courcy Williams, M.; Konstantinidis, K.; Rosa-Freitas, M. G.; Nearchou, A.; Gatzidou, E.; Veletza, S.; Boulougouris, G. C.; Dovrolis, N.; Karakasiliotis, I.
10.1101/2020.11.22.393140 — genomics — Posted on 2020-11-22
1107 Inhibition of Biofilm Formation by Modified Oxylipins from the Shipworm Symbiont Teredinibacter turnerae
Lacerna, N. M.; Ramones, C. M. V.; Robes, J. M. D.; Picart, M. R. D.; Tun, J. O.; Miller, B. W.; Haygood, M. G.; Schmidt, E. W.; Salvador-Reyes, L.; Concepcion, G. P.
10.1101/2020.11.22.393314 — microbiology — Posted on 2020-11-22
1112 Impact of transposable elements on the genome of the urban malaria vector Anopheles coluzzii
Vargas-Chavez, C.; Longo Pendy, N. M.; Nsango, S.; Aguilera, L.; Ayala, D.; Gonzalez, J.
10.1101/2020.11.22.393231 — genomics — Posted on 2020-11-22
1116 Patient-derived Glioblastoma Stem cells transfer mitochondria through Tunneling Nanotubes in Tumor Organoids
PINTO, G.; SAENZ DE SANTA MARIA, I.; CHASTAGNER, P.; Perthame, E.; DELMAS, C.; TOULAS, C.; Moyal-Jonathan-Cohen, E.; BROU, C.; ZURZOLO, C.
10.1101/2020.11.21.392597 — cancer biology — Posted on 2020-11-22
1118 Circadian fluctuations in glucocorticoid level impact perceptual sensitivity
Obleser, J.; Kreitewolf, J.; Vielhauer, R.; Lindner, F.; David, C.; Oster, H.; Tune, S.
10.1101/2020.10.07.330282 — neuroscience — Posted on 2020-11-22
1119 A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
Abassah-Oppong, S.; Mannion, B.; Tissieres, V.; Rodriguez-Carballo, E.; Ljubojevic, A.; Darbellay, F.; Festa, T. A.; Sullivan, C. S.; Kelman, G.; Hunter, R. D.; Novak, C. S.; Plajzer-Frick, I.; Tran, S.; Akiyama, J. A.; Barozzi, I.; Andrey, G.; Lopez-Rios, J.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.; Cobb, J.; Osterwalder, M.
10.1101/2020.11.22.393173 — developmental biology — Posted on 2020-11-22
1120 Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 in vitro
Le-Trilling, V. T. K.; Mennerich, D.; Schuler, C.; Flores-Martinez, Y.; Katschinski, B.; Dittmer, U.; Trilling, M.
10.1101/2020.11.18.388710 — microbiology — Posted on 2020-11-22
1121 Language network connectivity increases in prodromal Alzheimer's disease
Pistono, A.; Senoussi, M.; Guerrier, L.; Rafiq, M.; Gimeno, M.; Peran, P.; Jucla, M.; Pariente, J.
10.1101/2020.11.22.393199 — neuroscience — Posted on 2020-11-22
1122 Gut microbiome activity contributes to individual variation in glycemic response in adults
Tily, H.; Perlina, A.; Patridge, E.; Gline, S.; Genkin, M.; Gopu, V.; Lindau, H.; Sjue, A.; Slavov, I.; Klitgord, N.; Vuyisich, M.; Messier, H.; Banavar, G. S.
10.1101/641019 — systems biology — Posted on 2020-11-22
1129 Metabolic profile discriminates and predicts Arabidopsis susceptibility to virus under field conditions
Rubio, B.; Fernandez, O.; Cosson, P.; Berton, T.; Caballero, M.; Roux, F.; Bergelson, J.; Gibon, Y.; Schurdi-Levraud, V.
10.1101/2020.11.21.392688 — plant biology — Posted on 2020-11-22
1130 STAT3 inhibits Myocardin induced cardiac hypertrophy
Liao, X.-H.; Xiang, Y.; Li, J.-P.; Li, H.; Huang, Y.; Shen, C.; zhang, Z.; Zhang, T.-C.
10.1101/2020.11.21.392902 — cell biology — Posted on 2020-11-22
1131 Correcting for Superficial Bias in 7T Gradient Echo fMRI
Huang, P.; Correia, M. M.; Rua, C.; Rodgers, C. T.; Henson, R. N.; Carlin, J. D.
10.1101/2020.11.20.392258 — neuroscience — Posted on 2020-11-22
1134 Patient-derived Glioblastoma Stem cells transfer mitochondria through Tunneling Nanotubes in Tumor Organoids
ZURZOLO, C.; PINTO, G.; SAENZ DE SANTA MARIA, I.; CHASTAGNER, P.; Perthame, E.; DELMAS, C.; TOULAS, C.; Moyal-Jonathan-Cohen, E.; BROU, C.
10.1101/2020.11.21.392597 — cancer biology — Posted on 2020-11-22
1135 Public LC-Orbitrap-MS/MS Spectral Library for Metabolite Identification
Phapale, P.; Palmer, A.; Gathungu, R. M.; Kale, D.; Brugger, B.; Alexandrov, T.
10.1101/2020.11.21.392266 — biochemistry — Posted on 2020-11-22
1136 Automatic Analysis of Bees' Waggle Dance
Reece, J.; Couvillon, M. J.; Grueter, C.; Ratnieks, F.; Reyes-Aldasoro, C. C.
10.1101/2020.11.21.354019 — animal behavior and cognition — Posted on 2020-11-22
1137 Influence of spatial arrangement, biofertilizers and bioirrigation on the performance of legume-millet intercropping system in rainfed areas of southern India
Singh, D.; Mathimaran, N.; Sekar, J.; Ramalingam, P. V.; Perisamy, Y.; Raju, K.; Raj, R.; King, I. O.; Nanjundegowda, T. M.; Narayanswamy, M. B.; Chikkegowda, B. N.; Siddegowda, S. M.; Bagyaraj, D. J.; Maeder, P.; Boller, T.; Kahmen, A.
10.1101/2020.11.20.387886 — ecology — Posted on 2020-11-22
1138 DNA methylation age analysis of rapamycin in common marmosets
Horvath, S.; Zoller, J. A.; Haghani, A.; Lu, A.; Lu, A. T.; Raj, K.; Jasinska, A. J.; Mattison, J. A.; Salmon, A. B.
10.1101/2020.11.21.392779 — developmental biology — Posted on 2020-11-22
1139 Mechanosensitive Ion Channel Piezo1 Regulates Myocyte Fusion during Skeletal Myogenesis
Ortuste Quiroga, H. P.; Yokoyama, S.; Ganassi, M.; Nakamura, K.; Yamashita, T.; Raimbach, D.; Hagiwara, A.; Asakura, A.; Suzuki, Y.; Tominaga, M.; Zammit, P. S.; Goto, K.
10.1101/2020.09.27.315242 — molecular biology — Posted on 2020-11-22
1140 N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand
Ogawa, A.; Nagiri, C.; Shihoya, W.; Inoue, A.; Kawakami, K.; Hiratsuka, S.; Aoki, J.; Ito, Y.; Suzuki, T.; Suzuki, T.; Inoue, T.; Nureki, O.; Tanihara, H.; Tomizawa, K.; Wei, F.-Y.
10.1101/2020.11.21.391136 — molecular biology — Posted on 2020-11-22
1141 Novel Cluster AZ Arthrobacter phages Powerpuff, Lego, and YesChef exhibit close functional relationships with Microbacterium phages
Kapinos, A.; Aghamalian, P.; Capehart, E.; Alag, A.; Angel, H.; Briseno, E.; Choe, E.; Corado-Perez, B.; Farag, E.; Foster, H.; Hakim, A.; Hernandez-Casas, D.; Huang, C.; Lam, D.; Mendez, M.; Min, A.; Nguyen, N.; Omholt, A. L.; Ortiz, E.; Saldivar, L. S.; Shannon, J. A.; Smith, R.; Sridhar, M. V.; Ta, A.; Theophilus, M. C.; Wang, S.; Ngo, R.; Torres, C.; Reddi, K.; Freise, A. C.; Moberg Parker, J.
10.1101/2020.11.21.392811 — microbiology — Posted on 2020-11-22
1144 Women with a history of previous childbirths show less evident white matter brain ageing
Voldsbekk, I.; Barth, C.; Maximov, I. I.; Kaufmann, T.; Beck, D.; Richard, G.; Moberget, T.; Westlye, L. T.; de Lange, A.-M. G.
10.1101/2020.11.20.391698 — neuroscience — Posted on 2020-11-22
1150 A comprehensive analysis of the global human gut archaeome from a thousand genome catalogue
Chibani, C. M.; Mahnert, A.; Borrel, G.; Almeida, A.; Werner, A.; Brugere, J.-F.; Gribaldo, S.; Finn, R. D.; Schmitz, R. A.; Moissl-Eichinger, C.
10.1101/2020.11.21.392621 — bioinformatics — Posted on 2020-11-22
1151 A CDK-regulated chromatin segregase promoting chromosome replication
Chacin, E.; Bansal, P.; Reusswig, K.-U.; Diaz-Santin, L.; Ortega, P.; Vizjak, P.; Gomez-Gonzalez, B.; Mueller-Planitz, F.; Aguilera, A.; Pfander, B.; Cheung, A.; Kurat, C.
10.1101/2020.11.20.390914 — biochemistry — Posted on 2020-11-22
1152 CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation
Brilot, A. F.; Lyon, A.; Zelter, A.; Viswanath, S.; Maxwell, A.; MacCoss, M. J.; Muller, E. G.; Sali, A.; Davis, T. N.; Agard, D. A.
10.1101/2020.11.21.392803 — biochemistry — Posted on 2020-11-22
1153 Crosstalk between repair pathways elicits Double-Strand Breaks in alkylated DNA: implications for the action of temozolomide
FUCHS, R. P.; Isogawa, A.; Paulo, J. A.; Onizuka, K.; Takahashi, T.; Amunugama, R.; Duxin, J. P.; Fujii, S.
10.1101/2020.11.21.391326 — biochemistry — Posted on 2020-11-22
1155 A conserved strategy for inducing appendage regeneration
Abrams, M. J.; Tan, F. H.; Basinger, T.; Heithe, M. L.; Li, Y.; Raffiee, M.; Leahy, P.; Dabiri, J. O.; Gold, D. A.; Goentoro, L. A.
10.1101/2020.11.21.392720 — evolutionary biology — Posted on 2020-11-22
1158 Lipidomic analysis of roseobacters of the pelagic RCA cluster and their response to phosphorus limitation
Silvano, E.; Wolterink., M.; Giebel, H.; Simon, M.; Scanlan, D.; Zhao, Y.; Chen, Y.; Yang, M.
10.1101/2020.11.21.392431 — microbiology — Posted on 2020-11-22
1159 Transmission and protection against re-infection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate
Patel, D. R.; Field, C. J.; Septer, K. M.; SIm, D. G.; Jones, M. J.; Heinly, T. A.; McGraw, E. A.; Sutton, T. C.
10.1101/2020.11.20.392381 — microbiology — Posted on 2020-11-22
1160 Salicylate, Bile Acids and Extreme Acid Cause Fitness Tradeoffs for Multidrug Pumps in Escherichia coli K-12
Schaffner, S. H.; Lee, A. V.; Pham, M. T.; Kassaye, B. B.; Li, H.; Tallada, S.; Lis, C.; Lang, M.; Liu, Y.; Ahmed, N.; Galbraith, L. G.; Moore, J. P.; Bischof, K. M.; Slonczewski, J. L.
10.1101/2020.11.21.392837 — microbiology — Posted on 2020-11-22
1161 Harmonization of whole genome sequencing for outbreak surveillance of Enterobacteriaceae and Enterococci
Jamin, C.; de Koster, S.; van Koeveringe, S.; de Coninck, D.; Mensaert, K.; de Bruyne, K.; Perales Selva, N.; Lammens, C.; Goossens, H.; Hoebe, C. J.; Savelkoul, P.; van Alphen, L. B.
10.1101/2020.11.20.392399 — microbiology — Posted on 2020-11-22
1162 Anti-COVID-19 efficacy of ivermectin in the golden hamster
de Melo, G. D.; Lazarini, F.; Larrous, F.; Feige, L.; Kergoat, L.; Marchio, A.; Pineau, P.; Lecuit, M.; Lledo, P.-M.; Changeux, J.-P.; Bourhy, H.
10.1101/2020.11.21.392639 — immunology — Posted on 2020-11-22
1166 Systematic quantification of health parameters from UK Biobank abdominal MRI using deep learning
Liu, Y.; Basty, N.; Whitcher, B.; Bell, J.; Sorokin, E.; van Bruggen, N.; Thomas, E. L.; Cule, M.
10.1101/2020.07.14.187070 — genetics — Posted on 2020-11-21
1167 Predicting MEG resting-state functional connectivity using microstructural information
Messaritaki, E.; Foley, S.; Schiavi, S.; Magazzini, L.; Routley, B.; Jones, D. K.; Singh, K. D.
10.1101/2020.09.15.298307 — neuroscience — Posted on 2020-11-21
1168 Loss of integration of brain networks after sleep deprivation relates to the worsening of cognitive functions
Pesoli, M.; Rucco, R.; Liparoti, M.; Lardone, A.; D'Aurizio, G.; Minino, R.; Troisi Lopez, E.; Paccone, A.; Granata, C.; Sorrentino, G.; Mandolesi, L.; Sorrentino, P.
10.1101/2020.07.15.197590 — neuroscience — Posted on 2020-11-21
1169 The role of dopamine in reward-based motor adaptation, savings, and interference
Palidis, D. J.; McGregor, H. R.; Vo, A.; MacDonald, P. A.; Gribble, P. L.
10.1101/2020.11.19.390302 — neuroscience — Posted on 2020-11-21
1172 Sex of donor cell and reprogramming conditions predict the extent and nature of imprinting defects in mouse iPSCs
Arez, M.; Eckersley-Maslin, M.; Klobucar, T.; von Gilsa Lopes, J.; Krueger, F.; Raposo, A.; Gendrel, A.-V.; Bernardes de Jesus, B.; Teixeira da Rocha, S.
10.1101/2020.11.20.370973 — molecular biology — Posted on 2020-11-21
1173 AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia
Poh, L.; Fann, D.; Wong, P.; Lim, H. M.; Foo, S. L.; Kang, S.-W.; Rajeev, V.; Selvaraji, S.; Rajagopal Iyer, V.; Parathy, N.; Khan, M. B.; Hess, D. C.; Jo, D.-G.; Drummond, G. R.; Sobey, C. G.; Lai, M. K. P.; Chen, C. L.-H.; Lim, L. H. K.; Arumugam, T. V.
10.1101/2020.06.05.135228 — neuroscience — Posted on 2020-11-21
1174 Distinct and Common Neural Coding of Semantic and Non-semantic Control Demands
Gao, Z.; Zheng, L.; Chiou, R.; Gouws, A.; Krieger-Redwood, K.; Wang, X.; Varga, D.; Lambon Ralph, M.; Smallwood, J.; Jefferies, E.
10.1101/2020.11.16.384883 — neuroscience — Posted on 2020-11-21
1175 Reduction in CD11c+ microglia promotes clinical progression in autoimmune demyelination
Mayrhofer, F.; Dariychuk, Z.; Zhen, A.; Daugherty, D. J.; Bannerman, P.; Hanson, A. M.; Pleasure, D. E.; Soulika, A.; Deng, W.; Chechneva, O.
10.1101/396036 — neuroscience — Posted on 2020-11-21
1183 Dilp8 controls a time window for tissue size adjustment in Drosophila
Boulan, L.; Blanco-Obregon, D.; El Marzkioui, K.; Brutscher, F.; Andersen, D. S.; Colombani, J.; Narasimha, S.; Leopold, P.
10.1101/2020.11.09.375063 — developmental biology — Posted on 2020-11-21
1189 Comparative biochemistry of four polyester (PET) hydrolases
Arnling Baath, J.; Borch, K.; Jensen, K.; Brask, J.; Westh, P.
10.1101/2020.11.20.392019 — biochemistry — Posted on 2020-11-21
1190 The impact of biological sex on alternative splicing
Karlebach, G.; Veiga, D. F. T.; Deslattes Mays, A.; Chatzipantsiou, C.; Prieto Barja, P.; Chatzou, M.; Kesarwani, A. K.; Danis, D.; Kararigas, G.; Zhang, X. A.; George, J.; Steinhaus, R.; Hansen, P.; Seelow, D.; McMurry, J. A.; Haendel, M. A.; Yang, J.; Oprea, T.; Anczukow, O.; Banchereau, J.; Robinson, P. N.
10.1101/490904 — genomics — Posted on 2020-11-21
1192 Three-dimensional interrelationship between osteocyte network and forming mineral during human bone remodeling
Ayoubi, M.; van Tol, A. F.; Weinkamer, R.; Roschger, P.; Brugger, P.; Berzlanovich, A.; Bertinetti, L.; Roschger, A.; Fratzl, P.
10.1101/2020.11.20.391862 — biophysics — Posted on 2020-11-21
1193 KIR2DL4 genetic diversity in a Brazilian population sample: implications for transcription regulation and protein diversity in samples with different ancestry backgrounds
Weiss, E.; Andrade, H. S.; Lara, J. R.; Souza, A. S.; Paz, M. A.; Lima, T. A.; Porto, I. O.; Silva, N. S.; Castro, C. F.; Grotto, R.; Donadi, E. A.; Mendes-Junior, C. T.; Castelli, E. C.
10.1101/2020.11.20.391649 — genetics — Posted on 2020-11-21
1194 Convergent consequences of parthenogenesis on stick insect genomes
Jaron, K. S.; Parker, D. J.; Anselmetti, Y.; Tran Van, P.; Bast, J.; Dumas, Z.; Figuet, E.; Francois, C. M.; Hayward, K.; Rossier, V.; Simion, P.; Robinson-Rechavi, M.; Galtier, N.; Schwander, T.
10.1101/2020.11.20.391540 — evolutionary biology — Posted on 2020-11-21
1195 Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis
Lohoff, T.; Ghazanfar, S.; Missarova, A.; Koulena, N.; Pierson, N.; Griffiths, J. A.; Bardot, E. S.; Eng, C.-H. L.; Tyser, R. C. V.; Argelaguet, R.; Guibentif, C.; Srinivas, S.; Briscoe, J.; Simons, B. D.; Hadjantonakis, A.-K.; Gottgens, B.; Reik, W.; Nichols, J.; Cai, L.; Marioni, J. C.
10.1101/2020.11.20.391896 — developmental biology — Posted on 2020-11-21
1196 Microbial Metagenomic Approach Uncovers the First Rabbit Haemorrhagic Disease Virus genome in Sub-Saharan Africa
Happi, A. N.; Ogunsanya, O. A.; Oguzie, J.; Oluniyi, P. E.; Olono, A. S.; Heeney, J. L.; Happi, C.
10.1101/2020.11.19.390559 — molecular biology — Posted on 2020-11-21
1197 Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3
Beghini, F.; McIver, L. J.; Blanco-Miguez, A.; Dubois, L.; Asnicar, F.; Maharjan, S.; Mailyan, A.; Thomas, A. M.; Manghi, P.; Valles-Colomer, M.; Weingart, G.; Zhang, Y.; Zolfo, M.; Huttenhower, C.; Franzosa, E. A.; Segata, N.
10.1101/2020.11.19.388223 — microbiology — Posted on 2020-11-21
1198 A single bacterial sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium
Luis, A. S.; Jin, C.; Vasconcelos Pereira, G.; Glowacki, R. W. P.; Gugel, S.; Singh, S.; Byrne, D. P.; Pudlo, N. A.; London, J. A.; Basle, A.; Reihill, M.; Oscarson, S.; Eyers, P.; Czjzek, M.; Michel, G.; Barbeyron, T.; Yates, E. A.; Hansson, G. C.; Karlsson, N. G.; Cartmell, A.; Martens, E. C.
10.1101/2020.11.20.392076 — microbiology — Posted on 2020-11-21
1201 IBEX: A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues
Radtke, A. J.; Kandov, E.; Lowekamp, B.; Speranza, E.; Chu, C. J.; Gola, A.; Thakur, N.; Shih, R.; Yao, L.; Yaniv, Z. R.; Beuschel, R. T.; Kabat, J.; Croteau, J.; Davis, J.; Hernandez, J. M.; Germain, R. N.
10.1101/2020.11.20.390690 — immunology — Posted on 2020-11-21
1202 High-Grade Serous Ovarian Tumor Cells Modulate NK Cell Function to Create an Immune-Tolerant Microenvironment
Gonzalez, V. D.; Huang, Y.-W.; Chen, S.-Y.; Delgado-Gonzalez, A.; Donoso, K.; Gentles, A.; Sachs, K.; Porpiglia, E.; Fantl, W.
10.1101/2020.11.20.391706 — immunology — Posted on 2020-11-21
1203 Individual and combined effects of Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) on striato-cortical connectivity in the human brain
Wall, M. B.; Freeman, T. P.; Hindocha, C.; Demetriou, L.; Ertl, N.; Freeman, A. M.; Jones, A. P. M.; Lawn, W.; Pope, R.; Mokrysz, C.; Solomons, D.; Statton, B.; Walker, H. R.; Yamamori, Y.; Yang, Z.; Yim, J. L. L.; Nutt, D. J.; Howes, O. D.; Curran, H. V.; Bloomfield, M.
10.1101/2020.11.20.391805 — neuroscience — Posted on 2020-11-21
1204 Age-Associated Insolubility of Parkin in Human Midbrain is Linked to Redox Balance and Sequestration of Reactive Dopamine Metabolites
Tokarew, J. M.; El Kodsi, D. N.; Lengacher, N. A.; Fehr, T. K.; Nguyen, A. P.; Shutinoski, B.; O'Nuallain, B.; Jin, M.; Khan, J.; Ng, A. C. H.; Li, J.; Jiang, Q.; Zhang, M.; Wang, L.; Sengupta, R.; Barber, K.; Tran, A.; Zandee, S.; Dong, X.; Scherzer, C. R.; Prat, A.; Tsai, E.; Takanashi, M.; Hattori, N.; Chan, J. A.; Zecca, L.; West, A.; Holmgren, A.; Puente, L.; Shaw, G. S.; Toth, G.; Woulfe, J.; Taylor, P.; Tomlinson, J. J.; Schlossmacher, M. G.
10.1101/2020.11.20.392175 — neuroscience — Posted on 2020-11-21
1205 Exploring the limits of ComBat method for multi-site diffusion MRI harmonization
Cetin-Karayumak, S.; Stegmayer, K.; Walther, S.; Szeszko, P. R.; Crow, T.; James, A.; Keshavan, M.; Kubicki, M.; Rathi, Y.
10.1101/2020.11.20.390120 — neuroscience — Posted on 2020-11-21
1206 The effects of different frequencies of rhythmic acoustic stimulation on gait kinematics and trunk sway in healthy elderly population
Minino, R.; Troisi Lopez, E.; Sorrentino, P.; Rucco, R.; Lardone, A.; Pesoli, M.; Tafuri, D.; Mandolesi, L.; Sorrentino, G.; Liparoti, M.
10.1101/2020.11.20.390955 — neuroscience — Posted on 2020-11-21
1207 DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics
Tam, V.; Chen, P.; Yee, A.; Solis, N.; Klein, T.; Kudelko, M.; Sharma, R.; Chan, W. C.; Overall, C. M.; Haglund, L.; Sham, P. C.; Cheah, K. S.; Chan, D.
10.1101/2020.07.11.192948 — systems biology — Posted on 2020-11-21
1209 ATP drives efficient terpene biosynthesis in marine thraustochytrids
Zhang, A.; Mernitz, K. A.; Wu, C.; Xiong, W.; He, Y.; Wang, G.; Wang, X.
10.1101/2020.11.20.391870 — systems biology — Posted on 2020-11-21
1212 Clipper: p-value-free FDR control on high-throughput data from two conditions
Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, L. D.; Li, W.; Li, J. J.
10.1101/2020.11.19.390773 — bioinformatics — Posted on 2020-11-21
1213 Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
Dalvie, N. C.; Brady, J. R.; Crowell, L. E.; Tracey, M. K.; Biedermann, A. M.; Kaur, K.; Hickey, J. M.; Kristensen, D. L.; Bonnyman, A.; Rodriguez-Aponte, S. A.; Whittaker, C. A.; Bok, M.; Vega, C.; Mukhopadhyay, T.; Joshi, S. B.; Volkin, D. B.; Parreno, V.; Love, K. R.; Love, J. C.
10.1101/2020.11.20.391532 — bioengineering — Posted on 2020-11-20
1214 Dynamics of gene expression and chromatin marking during cell state transition
Borsari, B.; Abad, A.; Klein, C. C.; Nurtdinov, R.; Esteban, A.; Palumbo, E.; Ruiz-Romero, M.; Sanz, M.; Correa, B. R.; Johnson, R.; Perez-Lluch, S.; Guigo, R.
10.1101/2020.11.20.391524 — genomics — Posted on 2020-11-20
1215 Accurate Genomic Variant Detection in Single Cells with Primary Template-Directed Amplification
Gawad, C.; Klein, D.; Gonzalez-Pena, V.; Natarajan, S.; Carter, R.; Pruett-Miller, S. M.; Xia, Y.; Easton, J.; Chen, X.; Pang, Y.; Annu, K.; Shaner, B.; Putnam, D. K.; Chen, W.; Connelly, J.
10.1101/2020.11.20.391961 — genomics — Posted on 2020-11-20
1216 Transgenerational inheritance of BPA-induced obesity correlates with transmission of new CTCF sites in the Fto gene
Jung, Y. H.; Bixler, B. J.; Ruiz, D.; Wang, H.-L. V.; Linsenbaum, H.; Xiang, J.-F.; Shafik, A. M.; Jin, P.; Corces, V. G.
10.1101/2020.11.20.391672 — genomics — Posted on 2020-11-20
1217 Scalable pooled CRISPR screens with single-cell chromatin accessibility profiling
Liscovitch-Brauer, N.; Montalbano, A.; Deng, J.; Mendez-Mancilla, A.; Wessels, H.-H.; Moss, N. G.; Kung, C.-Y.; Sookdeo, A.; Guo, X.; Geller, E.; Jaini, S.; Smibert, P.; Sanjana, N. E.
10.1101/2020.11.20.390971 — genomics — Posted on 2020-11-20
1219 Impacts of water quality on Acropora coral settlement: The relative importance of substrate quality and light
Ricardo, G. F.; Harper, C. E.; Negri, A. P.; Luter, H. M.; Abdul Wahab, M. A.; Jones, R. J.
10.1101/2020.11.19.390724 — ecology — Posted on 2020-11-20
1223 Control of mitochondrial superoxide production includes programmed mtDNA deletion and restoration
Stenberg, S.; Li, J.; Gjuvsland, A. B.; Persson, K.; Demitz-Helin, E.; Yue, J.-X.; Gilchrist, C.; Ärengard, T.; Ghiaci, P.; Larsson-Berglund, L.; Zackrisson, M.; Höög, J. L.; Molin, M.; Liti, G.; Omholt, S. W.; Warringer, J.
10.1101/2020.11.20.391110 — cell biology — Posted on 2020-11-20
1224 Breast cancer dormancy is associated with a 4NG1 state and not senescence
Prunier, C.; Alay, A.; van Dijk, M.; Ammerlaan, K. L.; van Gelderen, S.; Marvin, D. L.; Teunisse, A.; Slieker, R. C.; Szuhai, K.; Jochemsen, A. G.; Sole, X.; ten Dijke, P.; Ritsma, L.
10.1101/2020.11.20.367698 — cell biology — Posted on 2020-11-21
1225 Spatio-temporal Control of ERK Pulse Frequency Coordinates Fate Decisions during Mammary Acinar Morphogenesis
Ender, P.; Gagliardi, P. A.; Dobrzynski, M.; Dessauges, C.; Höhener, T.; Jacques, M.-A.; Cohen, A. R.; Pertz, O.
10.1101/2020.11.20.387167 — cell biology — Posted on 2020-11-21
1227 Functional self-nonamerization of the Type III translocase chaperone/exported protein receptor
Yuan, B.; Portaliou, A. G.; Li, Y.; Wald, J.; Smit, J. H.; Dhupar, H. S.; Srinivasu, B. Y.; Loos, M. S.; Kalodimos, C. G.; Duong, F.; Cordes, T.; Marlovits, T. C.; Economou, A.; Karamanou, S.
10.1101/2020.11.20.391094 — molecular biology — Posted on 2020-11-20
1228 Antibiotic resistance profiles and population structure of disease-associated Staphylococcus aureus infecting patients in Fort Portal Regional Referral Hospital, Western Uganda
Ackers-Johnson, G.; Kibombo, D.; Kusiima, B.; Nsubuga, M.; Kigozi, E.; Kajumbula, H. M.; Kateete, D. P.; Walwema, R.; Ackers, H. L.; Goodhead, I. B.; Birtles, R. J.; James, C. E.
10.1101/2020.11.20.371203 — microbiology — Posted on 2020-11-21
1229 Temporal dynamics of animacy categorization in the brain of patients with mild cognitive impairment
Karimi, H.; Marefat, H.; Khanbagi, M.; Kalafatis, C.; Modarres, M. H.; Vahabi, Z.; Khaligh-Razavi, S.-M.
10.1101/2020.11.20.390435 — neuroscience — Posted on 2020-11-20
1230 Genome-wide screen of genomic imprinting in endosperm and population-level analysis reveal allelic variation for imprinting in flax
Jiang, H.; Guo, D.; Ye, J.; Gao, Y.; Liu, H.; Wang, Y.; Xue, M.; Yan, Q.; Chen, J.; Duan, L.; Li, G.; Li, X.; Xie, L.
10.1101/2020.11.20.390799 — plant biology — Posted on 2020-11-20
1233 STATegra: Multi-omics data integration - A conceptual scheme with a bioinformatics pipeline
Planell, N.; Lagani, V.; Sebastian-Leon, P.; van der Kloet, F.; Ewing, E.; Karathanasis, N.; Urdangarin, A.; Arozarena, I.; Jagodic, M.; Tsamardinos, I.; Tarazona, S.; Conesa, A.; tegner, j.; Gomez-Cabrero, D.
10.1101/2020.11.20.391045 — bioinformatics — Posted on 2020-11-20
1235 Interaction of Amphiphilic Lipoarabinomannan with Host Carrier Lipoproteins in Tuberculosis Patients: Implications for Blood-based Diagnostics.
Mukundan, H.; Jakhar, S.; Sakamuri, R.; Vu, D.; Dighe, P.; Stromberg, L. R.; Lilley, L.; Hengartner, N.; Swanson, B. I.; Moreau, E.; Dorman, S. E.
10.1101/2020.11.20.391037 — microbiology — Posted on 2020-11-20
1237 Could TDX-1 explain the changes observed in endocrine pancreas due to chronic cola drink consumption in rats? A global point of view
Cao, G.; Gonzalez, J.; Ortiz Fragola, J. P.; Muller, A.; Tumarkin, M.; Moriondo, M.; Azzato, F.; Blanco, M. V.; Milei, J.
10.1101/2020.11.20.391060 — systems biology — Posted on 2020-11-20
1241 Motor sequence learning deficits in idiopathic Parkinsons disease are associated with increased substantia nigra activity
Tzvi, E.; Bey, R.; Nitschke, M.; Brueggemann, N.; Classen, J.; Muente, T. F.; Kraemer, U. M.; Rumpf, J.-J.
10.1101/2020.11.19.386193 — neuroscience — Posted on 2020-11-20
1242 Single-cell landscape of nuclear configuration and gene expression during stem cell differentiation and X inactivation
Bonora, G.; Ramani, V.; Singh, R.; Fang, H.; Jackson, D.; Srivatsan, S.; Qiu, R.; Lee, C.; Trapnell, C.; Shendure, J.; Duan, Z.; Deng, X.; Noble, W. S.; Disteche, C. M.
10.1101/2020.11.20.390765 — genomics — Posted on 2020-11-20
1243 Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins
Lee, C.; Cox, R.; Papoulas, O.; Horani, A.; Drew, K.; Devitt, C.; Brody, S. L.; Marcotte, E.; Wallingford, J. B.
10.1101/2020.04.21.052837 — cell biology — Posted on 2020-11-20
1245 mTORC1 activity is supported by spatial association with focal adhesions
Rabanal-Ruiz, Y.; Byron, A.; Wirth, A.; Madsen, R. R.; Sedlackova, L.; Hewitt, G.; Nelson, G.; Stingele, J.; Faessler, R.; Vanhaesebroeck, B.; Maddocks, O.; Ponimaskin, E.; Carroll, B.; Korolchuk, V. I.
10.1101/2020.11.20.391888 — cell biology — Posted on 2020-11-20
1247 BETA- AND GAMMA-SYNUCLEINS MODULATE SYNAPTIC VESICLE-BINDING OF ALPHA-SYNUCLEIN
Carnazza, K. E.; Komer, L.; Pineda, A.; Na, Y.; Ramlall, T.; Buchman, V. L.; Eliezer, D.; Sharma, M.; Burre, J.
10.1101/2020.11.19.390419 — neuroscience — Posted on 2020-11-20
1250 Coiled-coil and RPW8-type immune receptors function at the plasma membrane in a phospholipid dependent manner
Saile, S. C.; Ackermann, F. M.; Sunil, S.; Bayless, A.; Stoebbe, E.; Bonardi, V.; Wan, L.; Doumane, M.; Jaillais, Y.; Caillaud, M.-C.; Dangl, J. L.; Nishimura, M. T.; El Kasmi, F.
10.1101/2020.11.18.388520 — plant biology — Posted on 2020-11-20
1251 Manipulating phloem transport affects wood formation but not nonstructural carbon concentrations in an evergreen conifer
Rademacher, T.; Fonti, P.; LeMoine, J. M.; Fonti, M. V.; Basler, D.; Chen, Y.; Friend, A. D.; Seyednasrollah, B.; Eckes-Shephard, A. H.; Richardson, A. D.
10.1101/2020.09.25.313569 — plant biology — Posted on 2020-11-20
1252 Deletion of Letmd1 leads to the disruption of mitochondrial function in brown adipose tissue
Song, R.; Du, Y.; Li, P.; Liu, H.; Zheng, H.; Lu, X.; Wang, S.; Zhou, L.; Rahman, N. A.; Wolczynski, S.; Kretowski, A.; Ren, F.; Li, X.; Li, X.
10.1101/2020.11.18.388199 — physiology — Posted on 2020-11-20
1256 Rooting the animal tree of life
Li, Y.; Shen, X.-X.; Evans, B.; Dunn, C. W.; Rokas, A.
10.1101/2020.10.27.357798 — evolutionary biology — Posted on 2020-11-20
1258 Global regulatory transitions at core promoters demarcate the mammalian germline cycle
Cvetesic, N.; Borkowska, M.; Hatanaka, Y.; Yu, C.; Vincent, S. D.; Mueller, F.; Tora, L.; Leitch, H. G.; Hajkova, P.; Lenhard, B.
10.1101/2020.10.30.361865 — developmental biology — Posted on 2020-11-20
1259 Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Wang, L.; Astone, M.; Alam, S. K.; Zhu, Z.; Pei, W.; Frank, D. A.; Burgess, S. M.; Hoeppner, L. H.
10.1101/2020.10.27.358374 — molecular biology — Posted on 2020-11-20
1261 MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection
Khuzwayo, S.; Mthembu, M.; Meermeier, E. W.; Prakadan, S. M.; Kazer, S. W.; Bassett, T.; Nyamande, K.; Fakey Khan, D.; Maharaj, P.; Mitha, M.; Suleman, M.; Mhlane, Z.; Ramjit, D.; Khan, F.; Shalek, A. K.; Lewinsohn, D. M.; Ndung'u, T.; Wong, E. B.
10.1101/2020.11.19.389858 — immunology — Posted on 2020-11-20
1265 U-Net Model for Brain Extraction on Non-human Primates
Wang, X.; Li, X.-H.; Cho, J. W.; Russ, B.; Rajamani, N.; Omelchenko, A.; Ai, L.; Korchmaros, A.; Garcia-Saldivar, P.; Wang, Z.; Kalin, N. H.; Schroeder, C. E.; Craddock, R. C.; Fox, A. S.; Evans, A. C.; Messinger, A.; Milham, M. P.; Xu, T.
10.1101/2020.11.17.385898 — neuroscience — Posted on 2020-11-20
1266 NeuroGPU, software for NEURON modeling in GPU-based hardware
Ben-Shalom, R.; Athreya, N. S.; Cross, C.; Sanghevi, H.; Kim, K. G.; Ladd, A.; Korngreen, A.; Bouchard, K. E.; Bender, K. J.
10.1101/727560 — neuroscience — Posted on 2020-11-20
1267 Median/modal death ages of pooled European male cohorts were near-constant for ~25/30 years.
Clark, J. S. C.; Rydzewska, K.; Podsiadlo, K.; van de Wetering, T.; Ciechanowicz, A.
10.1101/2020.05.23.111971 — physiology — Posted on 2020-11-20
1268 Agreement Test Between The Six Minutes Walking Test And Four Meter Gait Speed
Nusdwinuringtyas, N.; Fransiska, T.; Sunaryo, P.; Triangto, K.; Dahlan, S.
10.1101/2020.11.20.391193 — physiology — Posted on 2020-11-20
1272 2019 Association of Biomolecular Resource Facilities Multi-Laboratory Data-Independent Acquisition Study
Neely, B. A.; Stemmer, P.; Searle, B. C.; Herring, L. E.; Martin, L.; Midha, M. K.; Phinney, B. S.; Shan, B.; Palmblad, M.; Wang, Y.; Jagtap, P. D.; Kirkpatrick, J. M.
10.1101/2020.11.20.391300 — bioinformatics — Posted on 2020-11-20
1274 CellRank for directed single-cell fate mapping
Lange, M.; Bergen, V.; Klein, M.; Setty, M.; Reuter, B.; Bakhti, M.; Lickert, H.; Ansari, M.; Schniering, J.; Schiller, H. B.; Pe'er, D.; Theis, F. J.
10.1101/2020.10.19.345983 — bioinformatics — Posted on 2020-11-20
1276 Systematic quantification of health parameters from UK Biobank abdominal MRI using deep learning
Liu, Y.; Basty, N.; Whitcher, B.; Bell, J.; Sorokin, E.; van Bruggen, N.; Thomas, E. L.; Cule, M.
10.1101/2020.07.14.187070 — genetics — Posted on 2020-11-20
1278 Are fleas highly modified Mecoptera? Phylogenomic resolution of Antliophora (Insecta: Holometabola)
Meusemann, K.; Trautwein, M.; Friedrich, F.; Beutel, R.; Wiegmann, B. M.; Donath, A.; Podsiadlowski, L.; Petersen, M.; Niehuis, O.; Mayer, C.; Bayless, K.; Shin, S.; Liu, S.; Hlinka, O.; Minh, B. Q.; Kozlov, A. M.; Morel, B.; Peters, R.; Bartel, D.; Grove, S.; Zhou, X.; Misof, B.; Yeates, D.
10.1101/2020.11.19.390666 — evolutionary biology — Posted on 2020-11-20
1279 Massive occurrence of benthic plastic debris at the abyssal seafloor beneath the Kuroshio Extension, the North West Pacific
Nakajima, R.; Tsuchiya, M.; Yabuki, A.; Masuda, S.; Kitahashi, T.; Nagano, Y.; Ikuta, T.; Isobe, N.; Nakata, H.; Ritchie, H.; Oguri, K.; Osafune, S.; Kawamura, K.; Suzukawa, M.; Yamauchi, T.; Iijima, K.; Yoshida, T.; Chiba, S.; Fujikura, K.
10.1101/2020.11.18.382754 — ecology — Posted on 2020-11-20
1280 Detecting flying insects using mega-nets and meta-barcoding
Svenningsen, C. S.; Froslev, T. G.; Bladt, J.; Pedersen, L. B.; Larsen, J. C.; Ejrnaes, R. S.; Flojgaard, C.; Hansen, A. J.; Heilmann-Clausen, J.; Dunn, R. R.; Tottrup, A. P.
10.1101/2020.11.19.389742 — ecology — Posted on 2020-11-20
1281 CD28 costimulatory domain protects against tonic signaling-induced functional impairment in CAR-Tregs
Lamarthee, B.; Marchal, A.; Charbonnier, S.; Blein, T.; Martin, E.; Vogt, K.; Titeux, M.; Delville, M.; Vincon, H.; Six, E.; Pallet, N.; Anglicheau, D.; Legendre, C.; Taupin, J.-L.; Sawitzki, B.; Latour, S.; Cavazzana, M.; Andre, I.; Zuber, J.
10.1101/2020.11.19.390450 — immunology — Posted on 2020-11-20
1286 Identification of alkylsalicylic acids in Lentisk oil (Pistacia lentiscus L.) and cytotoxicity on Human Normal Dermal Fibroblasts
BENALIA, N.; BOUMECHHOUR, A.; ORTIZ, S.; ECHAGUE, C. A.; ROSE, T.; FIEBICH, B. L.; CHEMAT, S.; MICHEL, S.; DEGUIN, B.; DAHAMNA, S.; BOUTEFNOUCHET, S.
10.1101/2020.11.17.373142 — pharmacology and toxicology — Posted on 2020-11-20
1287 Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice
Kabbani, M.; Michailidis, E.; Steensels, S.; Fulmer, C. G.; Luna, J. M.; Le Pen, J.; Tardelli, M.; Razooky, B.; Ricardo-Lax, I.; Zou, C.; Zeck, B.; Stenzel, A. F.; Quirk, C.; Foquet, L.; Ashbrook, A. W.; Schneider, W. M.; Belkaya, S.; Lalazar, G.; Liang, Y.; Pittman, M.; Devisscher, L.; Suemizu, H.; Theise, N. D.; Chiriboga, L.; Cohen, D. E.; Copenhaver, R.; Grompe, M.; Meuleman, P.; Ersoy, B. A.; Rice, C. M.; de Jong, Y. P.
10.1101/2020.11.19.387613 — pathology — Posted on 2020-11-20
1293 Arena3Dweb: Interactive 3D visualization of multilayered networks.
Karatzas, E.; Baltoumas, F. A.; Panayiotou, N. A.; Schneider, R.; Pavlopoulos, G. A.
10.1101/2020.11.20.391318 — bioinformatics — Posted on 2020-11-20
1295 Highly fluorescent biodegradable PLGA nano-carriers allows real-time tracking of individual particles in vivo
Khalin, I.; Severi, C.; Heimburger, D.; Wehn, A.; Hellal, F.; Reisch, A.; Klymchenko, A.; Plesnila, N.
10.1101/2020.11.19.385062 — bioengineering — Posted on 2020-11-20
1297 Whole Genome Sequence Analysis of Shigella from Malawi Identifies Fluoroquinolone Resistance
Stenhouse, G. E.; Jere, K. C.; Peno, C.; Bengtsson, R. J.; Chinyama, E.; Mandolo, J.; Cain, A. K.; Iturriza_Gomara, M.; Bar-Zeev, N.; Cunliffe, N. A.; Cornick, J.; Baker, K. S.
10.1101/2020.11.20.391235 — genomics — Posted on 2020-11-20
1299 Identification of high confidence human poly(A) RNA isoform scaffolds using nanopore sequencing
Mulroney, L.; Wulf, M. G.; Schildkraut, I.; Tzertzinis, G.; Buswell, J.; Jain, M.; Olsen, H.; Diekhans, M.; Correa, I. R.; Akeson, M.; Ettwiller, L.
10.1101/2020.11.18.389049 — genomics — Posted on 2020-11-20
1304 LncRNA H19X is required for placenta development and angiogenesis through regulating a noncoding RNA regulatory network
Li, T.; Cao, Y.; Zou, Y.; Ye, Y.; Wang, K.; Huang, G.; Li, X.; Zheng, R.; Tang, L.; Lv, J.; Yang, M.; He, J.; Zhang, X.; Bai, S.; Li, Q.; Qin, L.; Zhao, X. M.; Xu, W.
10.1101/2020.11.19.389940 — developmental biology — Posted on 2020-11-20
1305 Sex of donor cell and reprogramming conditions predict the extent and nature of imprinting defects in mouse iPSCs
Arez, M.; Eckersley-Maslin, M.; Klobucar, T.; von Gilsa Lopes, J.; Krueger, F. A.; Raposo, A.; Gendrel, A.-V.; Bernardes de Jesus, B.; Teixeira da Rocha, S.
10.1101/2020.11.20.370973 — molecular biology — Posted on 2020-11-20
1307 Ribonucleotide reductase, a novel target for gonorrhea
Narasimhan, J.; Letinski, S.; Jung, S.; Gerasyuto, A.; Wang, J.; Arnold, M.; Chen, G.; Hedrick, J.; Dumble, M.; Ravichandran, K.; Levitz, T.; Cui, C.; Drennan, C. L.; Stubbe, J.; Karp, G.; Branstrom, A.
10.1101/2020.11.19.389957 — microbiology — Posted on 2020-11-20
1309 Quantifying biofilm propagation on chemically modified surfaces
Halsted, M. C.; Bible, A. N.; Morrell-Falvey, J. L.; Retterer, S. T.
10.1101/2020.11.20.391797 — microbiology — Posted on 2020-11-20
1313 Complement Component 3 expressed by the endometrial ectopic tissue is involved in the endometriotic lesion formation through mast cell activation
Agostinis, C.; Zorzet, S.; Balduit, A.; Zito, G.; Mangogna, A.; Macor, P.; Romano, F.; Toffoli, M.; Belmonte, B.; Martorana, A.; Borelli, V.; Ricci, G.; Kishore, U.; Bulla, R.
10.1101/2020.11.19.389536 — immunology — Posted on 2020-11-20
1314 Pre-conditioning Modifies the Tumor Microenvironment to Enhance Solid Tumor CAR T Cell Efficacy and Endogenous Immunity
Murad, J. P.; Tilakawardane, D.; Park, A. K.; Kennewick, K. T.; Lopez, L. S.; Lee, H. J.; Gittins, B. J.; Chang, W.-C.; Tran, C. P.; Martinez, C.; Wu, A. M.; Reiter, R. E.; Dorff, T. B.; Forman, S. J.; Priceman, S. J.
10.1101/2020.11.18.388892 — immunology — Posted on 2020-11-20
1320 The role of dopamine in reward-based motor adaptation, savings, and interference
Palidis, D. J.; McGregor, H. R.; Vo, A.; MacDonald, P. A.; Gribble, P. L.
10.1101/2020.11.19.390302 — neuroscience — Posted on 2020-11-20
1321 Elucidating the neuroanatomical correlates of social connectedness, sleep quality and psychological distress in early adolescence
Jamieson, D.; McLoughlin, L. T.; Beaudequin, D. A.; Shan, Z.; Boyes, A.; Schwenn, P.; Lagopoulos, J.; Hermens, D. F.
10.1101/2020.11.19.390336 — neuroscience — Posted on 2020-11-20
1325 Human iPSC-derived astrocytes transplanted into the mouse brain display three morphological responses to amyloid-β plaques
Preman, P.; TCW, J.; Calafate, S.; Snellinx, A.; Alfonso-Triguero, M.; Corthout, N.; Munck, S.; Thal, D. R.; Goate, A. M.; De Strooper, B.; Arranz, A. M.
10.1101/2020.11.19.389023 — neuroscience — Posted on 2020-11-20
1328 Mapping the contents of consciousness during musical imagery
Regev, M.; Halpern, A. R.; Owen, A. M.; Patel, A. D.; Zatorre, R. J.
10.1101/2020.11.20.391375 — neuroscience — Posted on 2020-11-20
1330 Spatio-temporal mRNA dynamics in the early zebrafish embryo
Holler, K.; Neuschulz, A.; Drewe-Boß, P.; Mintcheva, J.; Spanjaard, B.; Arsiè, R.; Ohler, U.; Landthaler, M.; Junker, J. P.
10.1101/2020.11.19.389809 — systems biology — Posted on 2020-11-20
1333 Deletion of Letmd1 leads to the disruption of mitochondrial function in brown adipose tissue
Song, R.; Du, Y.; Li, P.; Liu, H.; Zheng, H.; Lu, X.; Wang, S.; Zhou, L.; Rahman, N. A.; Wolczynski, S.; Kretowski, A.; Ren, F.; Li, X.; Li, X.
10.1101/2020.11.18.388199 — physiology — Posted on 2020-11-20
1334 A Unique Renal Architecture in Tribolium castaneum Informs the Evolutionary Origins of Systemic Osmoregulation in Beetles
Koyama, T.; Naseem, M. T.; Kolosov, D.; Vo, C. T.; Mahon, D.; Jakobsen, A. S. S.; Jensen, R. L.; Denholm, B.; O'Donnell, M.; Halberg, K. A.
10.1101/2020.11.19.389874 — physiology — Posted on 2020-11-20
1338 Small-molecule P2RX7 activator sensitizes tumor to immunotherapy and vaccinates mouse against tumor re-challenge
Douguet, L.; Janho dit hreich, S.; Benzaquen, J.; seguin, l.; Juhel, T.; Dezitter, X.; Duranton, C.; Ryffel, B.; Kanellopoulos, J.; Delarasse, C.; Renault, N.; Furman, C.; Homerin, G.; Feral, C.; Cherfils-Vicini, J.; Millet, R.; Adriouch, S.; Ghinet, A.; Hofman, P.; Vouret-Craviari, V.
10.1101/2020.11.19.388900 — cancer biology — Posted on 2020-11-20
1339 Cancer cells are sensitive to wild-type IDH1 inhibition under nutrient limitation
Vaziri-Gohar, A.; Hue, J. J.; Graor, H. J.; Prendergast, E.; Chen, V.; Cassel, J.; Mohammed, F. S.; Abbas, A.; Dukleska, K.; Khokhar, I.; Hajhassani, O.; Zarei, M.; Wang, R.; Rothermel, L. D.; Bederman, I.; Browers, J.; Getts, R.; Brunengraber, H.; Salvino, J. M.; Brody, J. R.; Winter, J. M.
10.1101/2020.11.19.390633 — cancer biology — Posted on 2020-11-20
1340 Clinical positioning of the IAP antagonist tolinapant (ASTX660) in colorectal cancer
Longley, D. B.; Crawford, N. T.; Stott, K. J.; Sessler, T.; McCann, C.; McDaid, W.; Latimer, C.; Fox, J.; Munck, J. M.; Smyth, T.; Shah, A.; Martins, V.; Lawler, M.; Dunne, P. D.; Kerr, E. M.; McDade, S. S.; Coyle, V. M.
10.1101/2020.11.20.391680 — cancer biology — Posted on 2020-11-20
1341 AMPGAN v2: Machine Learning Guided Discovery of Anti-Microbial Peptides
Van Oort, C. M.; Ferrell, J. B.; Remington, J. M.; Wshah, S.; Li, J.
10.1101/2020.11.18.388843 — biophysics — Posted on 2020-11-20
1343 BOSO: a novel feature selection algorithm for linear regression with high-dimensional data
Valcarcel, L. V.; San Jose-Eneriz, E.; Cendoya, X.; Rubio, A.; Agirre, X.; Prosper, F.; Planes, F. J.
10.1101/2020.11.18.388579 — bioinformatics — Posted on 2020-11-20
1344 SeRenDIP-CE: Sequence-based Interface Prediction for Conformational Epitopes
Hou, Q.; Stringer, B.; Waury, K.; Capel, H.; Haydarlou, R.; Abeln, S.; Heringa, J.; Feenstra, K. A.
10.1101/2020.11.19.390500 — bioinformatics — Posted on 2020-11-20
1346 Interactive design of GPU-accelerated Image Data Flow Graphs and cross-platform deployment using multi-lingual code generation
Haase, R.; Jain, A.; Rigaud, S.; Vorkel, D.; Rajasekhar, P.; Suckert, T.; Lambert, T. J.; Nunez-Iglesias, J.; Poole, D. P.; Tomancak, P.; Myers, E. W.
10.1101/2020.11.19.386565 — bioinformatics — Posted on 2020-11-20
1347 Efficient and precise single-cell reference atlas mapping with Symphony
Kang, J. B.; Nathan, A.; Millard, N.; Rumker, L.; Moody, D. B.; Korsunsky, I.; Raychaudhuri, S.
10.1101/2020.11.18.389189 — bioinformatics — Posted on 2020-11-20
1349 piNET: An Automated Proliferation Index Calculator Framework for Ki67 Breast Cancer Images
Geread, R. S.; Sivanandarajah, A.; Brouwer, E.; Wood, G.; Androutsos, D.; Faragalla, H.; Khademi, A.
10.1101/2020.11.19.390401 — bioinformatics — Posted on 2020-11-20
1355 Preliminary Minimum Reporting Requirements for Reporting In-Vivo Neural Interface Research: I. Implantable Neural Interfaces
Eiber, C. D.; Delbeke, J.; Cardoso, J.; de Neeling, M.; John, S.; Lee, C. W.; Skefos, J.; Sun, A.; Prodanov, D.; McKinney, Z.
10.1101/2020.11.18.375741 — bioengineering — Posted on 2020-11-20
1360 Bivariate genomic prediction of phenotypes by selecting epistatic interactions across years
Vojgani, E.; Pook, T.; Hoelker, A. C.; Mayer, M.; Schoen, C. C.; Simianer, H.
10.1101/2020.11.18.388330 — genetics — Posted on 2020-11-20
1361 Mono- and bi-allelic protein truncating variants in alpha-actinin 2 cause cardiomyopathy through distinct mechanisms
Lindholm, M. E.; Jimenez-Morales, D.; Zhu, H.; Seo, K.; Amar, D.; Zhao, C.; Raja, A.; Madhvani, R.; Espenel, C.; Sutton, S.; Caleshu, C.; Berry, G. J.; Motonaga, K. S.; Dunn, K.; Platt, J.; Ashley, E.; Wheeler, M. T.
10.1101/2020.11.19.389064 — genetics — Posted on 2020-11-20
1365 A scalable method for identifying recombinants from unaligned sequences
Feng, Q.; Tiedje, K.; Ruybal-Pesantez, S.; Tonkin-Hill, G.; Duffy, M.; Day, K.; Shim, H.; Chan, Y.-b.
10.1101/2020.11.18.389262 — evolutionary biology — Posted on 2020-11-20
1368 Loss of active neurogenesis in the adult shark retina
Hernandez-Nunez, I.; Robledo, D.; Mayeur, H.; Mazan, S.; Sanchez, L.; Adrio, F.; Barreiro-Iglesias, A.; Candal, E.
10.1101/2020.11.19.389973 — developmental biology — Posted on 2020-11-20
1369 Transcriptional regulation of EMT by nuclear MMP28
GOUIGNARD, N.; BIBONNE, A.; SAINT-JEANNET, J.-P.; THEVENEAU, E.
10.1101/2020.11.19.389544 — developmental biology — Posted on 2020-11-20
1373 Proteomics on longitudinal serum samples differentiates localized and disseminated Lyme disease
Fatou, B.; Smolen, K. K.; Belperron, A. A.; Wurie, Z.; Kleinstein, S.; Montgomery, R.; Levy, O.; Bockenstedt, L. K.; Steen, H.
10.1101/2020.11.18.387993 — immunology — Posted on 2020-11-20
1374 Preclinical validation of a second generation leishmanization vaccine against vector transmitted fatal visceral leishmaniasis
Nakhasi, H. L.; DEY, R.; Gannavaram, S.; Karmakar, S.; Bhattacharya, P.; Ismail, N.; Satoskar, A.; Volpedo, G.; Oliveira, L. F.; Oristian, J.; Meneses, C.; Valenzuela, J. G.; Kamhawi, S.; Zhang, W. W.; Matlashewski, G.; Hamano, S.; Satoskar, M.; Satoskar, S.; Sastry, R. M.; Kaviraj, S.; Singh, S.; Singh, K. P.; Das, S.; Das, P.; Mondal, A.; Pandey, K.
10.1101/2020.11.18.388553 — immunology — Posted on 2020-11-20
1375 Bacterial inhibition of CD8+ T-cells mediated cell death promotes neuroinvasion and within-host persistence
Maudet, C.; Kheloufi, M.; Levallois, S.; Gaillard, J.; Huang, L.; Gaultier, C.; Tsai, Y.-H.; Disson, O.; Lecuit, M.
10.1101/2020.11.20.384974 — immunology — Posted on 2020-11-20
1376 Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin
Elleman, A. V.; Devienne, G.; Makinson, C. D.; Haynes, A. L.; Huguenard, J. R.; Du Bois, J.
10.1101/2020.11.18.389130 — neuroscience — Posted on 2020-11-20
1381 Mapping the common and distinct neural correlates of visual, rule and motor conflict
Goulding Mew, B.; Custovic, D.; Soreq, E.; Lorenz, R.; Violante, I. R.; Sandrone, S.; Hampshire, A.
10.1101/2020.11.19.388231 — neuroscience — Posted on 2020-11-20
1383 Migraine Attacks as a Result of Hypothalamic Loss of Control
Stankewitz, A.; Keidel, L.; Rehm, M.; Irving, S.; Kaczmarz, S.; Preibisch, C.; Witkovsky, V.; Zimmer, C.; Schulz, E.; Toelle, T. R.
10.1101/2020.11.19.390104 — neuroscience — Posted on 2020-11-20
1389 The ant fungus garden acts as an external digestive system
Caraballo-Rodriguez, A. M.; Pucket, S. P.; Kyle, K. E.; Petras, D.; da Silva, R. R.; Nothias, L.-F.; Ernst, M.; van der Hooft, J. J. J.; Tripathi, A.; Wang, M.; Balunas, M. J.; Klassen, J. L.; Dorrestein, P. C.
10.1101/2020.11.18.389361 — systems biology — Posted on 2020-11-20
1390 Ancestral class-promiscuity as a driver of functional diversity in the BAHD acyltransferase family in plants
Kruse, L. H.; Weigle, A. T.; Martinez-Gomez, J.; Chobirko, J. D.; Schaffer, J. E.; Bennett, A. A.; Specht, C. D.; Jez, J. M.; Shukla, D.; Moghe, G. D.
10.1101/2020.11.18.385815 — plant biology — Posted on 2020-11-20
1391 Divergence in a stress-associated gene regulatory network underlies differential growth control in the Brassicaceae family
Sun, Y.; Oh, D.-H.; Duan, L.; Ramachandran, P.; Ramirez, A.; Bartlett, A.; Dassanayake, M.; Dinneny, J. R.
10.1101/2020.11.18.349449 — plant biology — Posted on 2020-11-20
1393 Diet and heat - one neuronal subset two responses
Prince, E.; Kretzschmar, J.; Trautenberg, L. C.; Brankatschk, M.
10.1101/2020.11.18.388017 — physiology — Posted on 2020-11-20
1395 Effects of Endogenous Angiotensin II on Abdominal Aortic Aneurysms and Atherosclerosis in Angiotensin II-infused Mice
Kukida, M.; Sawada, H.; Ohno-Urabe, S.; Howatt, D. A.; Moorleghen, J. J.; Poglitsch, M.; Daugherty, A.; Lu, H. S.
10.1101/2020.11.18.377416 — pathology — Posted on 2020-11-20
1397 Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity
Medina, L.; Gonzalez Lizarraga, F.; Dominguez Meijide, A.; Ploper, D.; Parrales, V.; Sequeira, S.; Cima Omorri, M. S.; Zweckstetter, M.; del Bel, E.; Michel, P. P.; Fleming Outeiro, T.; Raisman-Vozari, R.; Chehin, R. N.; Socias, S. B.
10.1101/2020.11.18.388561 — biophysics — Posted on 2020-11-20
1402 Cas12a-Capture: a novel, low-cost, and scalable method for targeted sequencing
Mighell, T. L.; Nishida, A.; O'Connell, B. L.; Miller, C. V.; Grindstaff, S.; Thornton, C. A.; Adey, A. C.; Doherty, D.; O'Roak, B. J.
10.1101/2020.11.18.388876 — genomics — Posted on 2020-11-20
1404 Taxonomic sampling and rare genomic changes overcome long-branch attraction in the phylogenetic placement of pseudoscorpions
Ontano, A. Z.; Gainett, G.; Aharon, S.; Ballesteros, J. A.; Benavides, L. R.; Corbett, K. F.; Gavish-Regev, E.; Harvey, M. S.; Monsma, S.; Santibanez-Lopez, C. E.; Setton, E. V.; Zehms, J. T.; Zeh, J. A.; Zeh, D. W.; Sharma, P. P.
10.1101/2020.11.18.389098 — evolutionary biology — Posted on 2020-11-20
1405 Two new hybrid zones expand the swordtail hybridization model system
Powell, D. L.; Moran, B.; Kim, B.; Banerjee, S. M.; Aguillon, S. M.; Fascinetto-Zago, P.; Langdon, Q.; Schumer, M.
10.1101/2020.11.18.389205 — evolutionary biology — Posted on 2020-11-20
1406 Dehydration risk, not ambient incubation, limits nest attendance at high temperatures
Bourne, A. R.; Ridley, A. R.; Mckechnie, A. E.; Spottiswoode, C. N.; Cunningham, S. J.
10.1101/2020.11.18.388025 — ecology — Posted on 2020-11-20
1409 Repeated blast mild traumatic brain injury and oxycodone self-administration produce interactive effects on neuroimaging outcomes
Muelbl, M. J.; Glaeser, B.; Shah, A. S.; Chiariello, R.; Nawarawong, N. N.; Stemper, B. D.; Budde, M. D.; Olsen, C. M.
10.1101/2020.11.18.388421 — neuroscience — Posted on 2020-11-20
1412 Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion
Slovakova, J.; Sikora, M.; Caballero-Mancebo, S.; Krens, G. S.; Heisenberg, C.-P.; Kaufmann, W. A.; Huljev, K.
10.1101/2020.11.20.391284 — cell biology — Posted on 2020-11-20
1414 Adipose Triglyceride Lipase protects the endocytosis of renal cells on a high fat diet in Drosophila
Lubojemska, A.; Stefana, M. I.; Lampe, L.; Yoshimura, A.; Burrell, A.; Collinson, L.; Gould, A. P.
10.1101/2020.11.19.390146 — cell biology — Posted on 2020-11-20
1416 ATP triggers macropinocytosis that internalizes and is regulated by PANX1
Boyce, A. K.; van der Slagt, E.; Sanchez-Arias, J. C.; Swayne, L. A.
10.1101/2020.11.19.389072 — cell biology — Posted on 2020-11-20
1417 Unscheduled origin building in S-phase upon tight CDK1 inhibition suppresses CFS instability
BRISON, O.; Gnan, S.; Azar, D.; Schmidt, M.; KOUNDRIOUKOFF, S.; El-Hilali, S.; Jaszczyszyn, Y.; Lachages, A.-M.; Thermes, C.; Chen, C.-L.; Debatisse, M.
10.1101/2020.11.19.390054 — cell biology — Posted on 2020-11-20
1418 A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins
Zhang, W.; Yang, X.; Chen, L.; Liu, Y.-Y.; Venkatarangan, V.; Reist, L.; Hanson, P.; Xu, H.; Wang, Y.; Li, M.
10.1101/2020.11.18.389296 — cell biology — Posted on 2020-11-20
1419 AI-Driven Multiscale Simulations Illuminate Mechanisms of SARS-CoV-2 Spike Dynamics
Casalino, L.; Dommer, A. C.; Gaieb, Z.; Barros, E. P.; Sztain, T.; Ahn, S.-H.; Trifan, A.; Brace, A.; Ma, H.; Lee, H.; Turilli, M.; Bogetti, A.; Khalid, S.; Chong, L.; Simmerling, C.; Hardy, D.; Maia, J.; Phillips, J.; Kurth, T.; Stern, A.; Huang, L.; McCalpain, J.; Tatineni, M.; Gibbs, T.; Stone, J. E.; Jha, S.; Ramanathan, A.; Amaro, R. E.
10.1101/2020.11.19.390187 — biophysics — Posted on 2020-11-20
1421 Fibroblastic Reticular Cell Response to Dendritic Cells Requires Coordinated Activity of Podoplanin, CD44 and CD9
de Winde, C. M.; Makris, S.; Millward, L.; Cantoral, J.; Benjamin, A. C.; Martinez, V. G.; Acton, S. E.
10.1101/793141 — cell biology — Posted on 2020-11-20
1422 Anti-severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) potency of Mefloquine as an entry inhibitor in vitro
Shionoya, K.; Yamasaki, M.; Iwanami, S.; Ito, Y.; Fukushi, S.; Ohashi, H.; Saso, W.; Tanaka, T.; Aoki, S.; Kuramochi, K.; Iwami, S.; Takahashi, Y.; Suzuki, T.; Muramatsu, M.; Takeda, M.; Wakita, T.; Watashi, K.
10.1101/2020.11.19.389726 — microbiology — Posted on 2020-11-20
1423 Highly potent anti-SARS-CoV-2 multi-DARPin therapeutic candidates
Walser, M.; Rothenberger, S.; Hurdiss, D. L.; Schlegel, A.; Calabro, V.; Fontaine, S.; Villemagne, D.; Paladino, M.; Hospodarsch, T.; Neculcea, A.; Cornelius, A.; Schildknecht, P.; Matzner, M.; Haenggi, M.; Franchini, M.; Kaufmann, Y.; Schaible, D.; Schlegel, I.; Iss, C.; Looser, T.; Mangold, S.; Herzog, C.; Schiegg, D.; Reichen, C.; Radom, F.; Bosshart, A.; Lehmann, A.; Haeuptle, M. A.; Zuercher, A.; Vagt, T.; Sigrist, G.; Straumann, M.; Proba, K.; Veitonmaki, N.; Dawson, K. M.; Zitt, C.; Mayor, J.; Ryter, S.; Lyoo, H.; Wang, C.; Li, W.; Drulyte, I.; Du, W.; Binz, H. K.; de Waal, L.; Stittela
10.1101/2020.08.25.256339 — immunology — Posted on 2020-11-20
1424 Multiscale three-dimensional pathology findings of COVID-19 diseased lung using high-resolution cleared tissue microscopy
Li, G.; Fox, S. E.; Summa, B.; Hu, B.; Wenk, C.; Akmatbekov, A.; Harbert, J. L.; Vander Heide, R. S.; Brown, J. Q.
10.1101/2020.04.11.037473 — pathology — Posted on 2020-11-20
1425 EcDNA hubs drive cooperative intermolecular oncogene expression
Hung, K. L.; Yost, K. E.; Xie, L.; Wu, S.; Lange, J. T.; Duffy, C. V.; Kraft, K.; Tang, J.; Shi, Q.; Rose, J. C.; Corces, M. R.; Granja, J. M.; Li, R.; Rajkumar, U.; Tjian, R.; Bafna, V.; Mischel, P. S.; Liu, Z.; Chang, H. Y.
10.1101/2020.11.19.390278 — cancer biology — Posted on 2020-11-20
1431 Production of anti-SARS-CoV-2 hyperimmune globulin from convalescent plasma
Vandeberg, P.; Cruz, M.; Diez, J. M.; Merritt, W. K.; Santos, B.; Trukawinski, S.; Wellhouse, A.; Jose, M.; Willis, T.
10.1101/2020.11.18.388991 — immunology — Posted on 2020-11-20
1432 Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum
Cochet-Escartin, O.; Demircigil, M.; Hirose, S.; Allais, B.; Gonzalo, P.; Mikaelian, I.; Calvez, V.; Funamoto, K.; Anjard, C.; Rieu, J.-P.
10.1101/2020.08.17.246082 — biophysics — Posted on 2020-11-20
1434 Asymmetric outcome of community coalescence of seed and soil microbiota during early seedling growth
Rochefort, A.; Simonin, M.; Marais, C.; Guillerm-Erckelboudt, A.-Y.; Barret, M.; Sarniguet, A.
10.1101/2020.11.19.390344 — microbiology — Posted on 2020-11-20
1435 NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers
Ong, C. E. B.; Patchett, A. L.; Darby, J. M.; Chen, J.; Liu, G.-S.; Lyons, A. B.; Woods, G. M.; Flies, A. S.
10.1101/2020.09.06.274720 — immunology — Posted on 2020-11-20
1437 Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington's disease
Casale, A. M.; Liguori, F.; Ansaloni, F.; Cappucci, U.; Finaurini, S.; Spirito, G.; Persichetti, F.; Sanges, R.; Gustincich, S.; Piacentini, L.
10.1101/2020.11.19.389718 — neuroscience — Posted on 2020-11-20
1440 Overlapping neural representations for the position of visible and imagined objects
Robinson, A. K.; Grootswagers, T.; Shatek, S. M.; Gerboni, J.; Holcombe, A. O.; Carlson, T. A.
10.1101/2020.03.02.974162 — neuroscience — Posted on 2020-11-20
1443 A single cell view of the transcriptome during lateral root initiation in Arabidopsis thaliana
Gala, H. P.; Lanctot, A. P.; Jean-Baptiste, K.; Guiziou, S.; Chu, J. C.; Zemke, J. E.; George, W.; Queitsch, C.; Cuperus, J.; Nemhauser, J.
10.1101/2020.10.02.324327 — plant biology — Posted on 2020-11-20
1444 YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER
Lefort, S.; El-Naggar, A.; Tan, S.; Colborne, S.; Negri, G. L.; Pellacani, D.; Hirst, M.; Gusterson, B.; Morin, G. B.; Sorensen, P. H.; Eaves, C. J.
10.1101/372524 — cancer biology — Posted on 2020-11-20
1445 GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions
BRUN, S.; Raymond, E.; Bassissi, F.; Jilkova, Z. M.; Mezouar, S.; Rachid, M.; Novello, M.; Tracz, J.; Hamai, A.; Lalmanach, G.; Vanderlynden, L.; Bestion, E.; Legouffe, R.; Stauber, J.; Schubert, T.; Plach, M. G.; Courcambeck, J.; Drouot, C.; Jacquemot, G.; Serdjebi, C.; Roth, G.; Baudoin, J.-P.; Ansaldi, C.; Decaens, T.; Halfon, P.
10.1101/2020.09.30.320010 — cancer biology — Posted on 2020-11-20
1446 Stromal Oncostatin M axis promotes breast cancer progression
Araujo, A. M.; Abaurrea, A.; Azcoaga, P.; Lopez-Velazco, J. I.; Rezola, R.; Osorio-Querejeta, I.; Valdes-Mora, F.; Flores, J. M.; Jenkins, L.; Fernandez-Nogueira, P.; Ferrari, N.; Martin-Martin, N.; Tzankov, A.; Eppenberger-Castori, S.; Alvarez-Lopez, I.; Urruticoechea, A.; Bragado, P.; Coleman, N.; Carracedo, A.; Gallego-Ortega, D.; Calvo, F.; Isacke, C. M.; Caffarel, M. M.; Lawrie, C. H.
10.1101/2020.10.30.356774 — cancer biology — Posted on 2020-11-20
1451 Transcriptional kinetics and molecular functions of long non-coding RNAs
Johnsson, P. A.; Ziegenhain, C.; Hartmanis, L.; Hendriks, G.-J.; Hagemann-Jensen, M.; Reinius, B.; Sandberg, R.
10.1101/2020.05.05.079251 — genomics — Posted on 2020-11-20
1452 Does diversity beget diversity in microbiomes?
Madi, N. J.; Vos, M.; Murall, C. L.; Legendre, P.; Shapiro, B. J.
10.1101/612739 — evolutionary biology — Posted on 2020-11-20
1454 The avian W chromosome is a refugium for endogenous retroviruses with likely effects on female-biased mutational load and genetic incompatibilities
Peona, V.; Palacios-Gimenez, O. M.; Blommaert, J.; Liu, J.; Haryoko, T.; Jonsson, K. A.; Irestedt, M.; Zhou, Q.; Jern, P.; Suh, A.
10.1101/2020.07.31.230854 — evolutionary biology — Posted on 2020-11-20
1455 Quantitative Mapping of Human Hair Graying and Reversal in Relation to Life Stress
Rosenberg, A.; Rausser, S.; Ren, J.; Mosharov, E.; Sturm, G. M.; Ogden, R. T.; Patel, P.; Soni, R. K.; Lacefield, C.; Tobin, D. J.; Paus, R.; Picard, M.
10.1101/2020.05.18.101964 — cell biology — Posted on 2020-11-20
1456 Adherent cell remodeling on micropatterns is modulated by Piezo1 channels
Jetta, D.; Bahrani Fard, M. R.; Sachs, F.; Munechika, K.; Hua, S. Z.
10.1101/2020.11.18.389106 — biophysics — Posted on 2020-11-20
1457 dsSwissKnife: An R package for federated data analysis
Dragan, I.; Sparso, T.; Kuznetsov, D.; Slieker, R.; Ibberson, M.
10.1101/2020.11.17.386813 — bioinformatics — Posted on 2020-11-20
1460 A Structural Signature Motif Enlightens the Origin and Diversification of Nuclear Receptors
Beinsteiner, B.; Markov, G. V.; Erb, S.; Chebaro, Y.; McEwen, A. G.; Sanglier Cianferani, S.; Laudet, V.; Moras, D.; Billas, I.
10.1101/2020.11.18.388405 — evolutionary biology — Posted on 2020-11-20
1463 High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism
Parlakgul, G.; Arruda, A. P.; Cagampan, E.; Pang, S.; Guney, E.; Lee, Y.; Hess, H. F.; Xu, C. S.; Hotamisligil, G. S.
10.1101/2020.11.18.387803 — cell biology — Posted on 2020-11-20
1465 U-Net Model for Brain Extraction on Non-human Primates
Wang, X.; Li, X.-H.; Cho, J. W.; Russ, B.; Rajamani, N.; Omelchenko, A.; Ai, L.; Korchmaros, A.; Garcia-Saldivar, P.; Wang, Z.; Kalin, N. H.; Schroeder, C. E.; Craddock, R. C.; Fox, A. S.; Evans, A. C.; Messinger, A.; Milham, M. P.; Xu, T.
10.1101/2020.11.17.385898 — neuroscience — Posted on 2020-11-20
1466 Rotational dynamics in motor cortex are consistent with a feedback controller
Kalidindi, H. T.; Cross, K. P.; Lillicrap, T. P.; Omrani, M.; Falotico, E.; Sabes, P. N.; Scott, S. H.
10.1101/2020.11.17.387043 — neuroscience — Posted on 2020-11-20
1467 Time-Encoding Migrates from Prefrontal Cortex to Dorsal Striatum During Learning of a Self-Timed Response Duration Task
Chiuffa Tunes, G.; de Oliveira, E. F.; Vieira, E. U. P.; Caetano, M. S.; Cravo, A. M.; Reyes, M. B.
10.1101/2020.11.19.390286 — neuroscience — Posted on 2020-11-20
1468 The human hippocampus plays a time-limited role in retrieving autobiographical memories
Gilmore, A. W.; Quach, A.; Kalinowski, S. E.; Gonzalez-Araya, E. I.; Gotts, S. J.; Schacter, D. L.; Martin, A.
10.1101/2020.11.19.390526 — neuroscience — Posted on 2020-11-19
1469 Aberrant gliogenesis and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
Trudler, D.; Ghatak, S.; Parker, J.; Talantova, M.; Grabauskas, T.; Noveral, S. M.; Teranaka, M.; Luevanos, M.; Dolatabadi, N.; Bakker, C.; Lopez, K.; Sultan, A.; Chan, A.; Choi, Y.; Kawaguchi, R.; Schork, N.; Stankiewicz, P.; Garcia-Bassets, I.; Kozbial, P.; Rosenfeld, M. G.; Nakanishi, N.; Geschwind, D.; Chan, S. F.; Ambasudhan, R.; Lipton, S. A.
10.1101/2020.11.19.387639 — neuroscience — Posted on 2020-11-19
1471 Oscillatory responses to generated and perceived rhythms
Ostarek, M.; Alday, P. M.; Gawel, O.; Wolfgruber, J.; Knudsen, B.; Mantegna, F.; Huettig, F.
10.1101/2020.11.19.390062 — neuroscience — Posted on 2020-11-19
1473 MLL1 is required for maintenance of intestinal stem cells and the expression of the cell adhesion molecule JAML
Goveas, N.; Waskow, C.; Arndt, K.; Heuberger, J.; Zhang, Q.; Alexopoulou, D.; Dahl, A.; Birchmeier, W.; Anastassiadis, K.; Stewart, A. F.; Kranz, A.
10.1101/2020.11.19.389528 — genetics — Posted on 2020-11-19
1482 Hundreds of nuclear and plastid loci yield insights into orchid relationships
Perez-Escobar, O. A.; Dodsworth, S.; Bogarin, D.; Bellot, S.; Balbuena, J. A.; Schley, R.; Kikuchi, I.; Morris, S. K.; Epitawalage, N.; Cowan, R.; Maurin, O.; Zuntini, A.; Arias, T.; Serna, A.; Gravendeel, B.; Torres, M. F.; Nargar, K.; Chomicki, G.; Chase, M.; Leitch, I. J.; Forest, F.; Baker, W. J.
10.1101/2020.11.17.386508 — evolutionary biology — Posted on 2020-11-19
1487 Chemoproteomics Maps Glycolytic Targetome in Cancer Cells
Tian, Y.; Wan, N.; Ding, M.; Shao, C.; Wang, N.; Bao, Q.; Lu, W.; Hu, H.; Sun, H.; Yang, C.; Zhou, K.; Chen, S.; Wang, G.; Ye, H.; Hao, H.
10.1101/2020.11.18.387670 — cancer biology — Posted on 2020-11-19
1490 Signatures Of TSPAN8 Variants Associated With Human Metabolic Regulation And Diseases
De, T.; Goncalves, A.; Speed, D.; Froguel, P.; NFBC Consortium, ; Gaffney, D.; Johnson, M. R.; Jarvelin, M.-R.; Coin, L.
10.1101/2020.11.17.386839 — genomics — Posted on 2020-11-19
1491 Fast neutron mutagenesis in soybean creates frameshift mutations
Wyant, S. R.; Rodriguez, M. F.; Carter, C. K.; Parrott, W. A.; Jackson, S. A.; Stupar, R. M.; Morrell, P. L.
10.1101/2020.11.17.387373 — genetics — Posted on 2020-11-19
1494 Generation of two Multipotent Mesenchymal Progenitor Cell Lines Capable of Osteogenic, Mature Osteocyte, Adipogenic, and Chondrogenic Differentiation
Prideaux, M.; Wright, C. S.; Noonan, M. L.; Yi, X.; Clinkenbeard, E. L.; Mevel, E.; Wheeler, J. A.; Byers, S.; Sankar, U.; White, K. E.; Atkins, G. J.; Thompson, W. R.
10.1101/2020.11.19.385138 — cell biology — Posted on 2020-11-19
1495 Type I PRMTs and PRMT5 Independently Regulate Both snRNP Arginine Methylation and Post-Transcriptional Splicing
Maron, M. I.; Burgos, E. S.; Gupta, V.; Casill, A. D.; Kosmyna, B.; Chen, H.; Gamble, M. J.; Query, C. C.; Shechter, D.
10.1101/2020.11.18.389288 — cell biology — Posted on 2020-11-19
1496 Cis regulation within a cluster of viral microRNAs
Vilimova, M.; Contrant, M.; Randrianjafy, R.; Dumas, P.; Pfeffer, S.; Fender, A.
10.1101/2020.11.19.389551 — molecular biology — Posted on 2020-11-19
1497 A human stem cell-derived neurosensory-epithelial circuitry on-a-chip to model herpes simplex virus reactivation
Mazzara, P. G.; Criscuolo, E.; Rasponi, M.; Massimino, L.; Muggeo, S.; Palma, C.; Castelli, M.; Clementi, M.; Burioni, R.; Mancini, N.; Broccoli, V.; Clementi, N.
10.1101/2020.11.19.390260 — microbiology — Posted on 2020-11-19
1499 Bat influenza vectored NS1-truncated live vaccine protects pigs against heterologous virus challenge
Lee, J.; Li, Y.; Li, Y.; Cino-Ozuna, G.; Duff, M.; Lang, Y.; Ma, J.; Sunwoo, S.; Richt, J. A.; Ma, W.
10.1101/2020.11.18.389254 — microbiology — Posted on 2020-11-19
1500 Selective vulnerability of supragranular layer neurons in schizophrenia
Batiuk, M. Y.; Tyler, T.; Mei, S.; Rydbirk, R.; Petukhov, V.; Sedmak, D.; Frank, E.; Feher, V.; Habek, N.; Hu, Q.; Igolkina, A.; Roszik, L.; Pfisterer, U.; Petanjek, Z.; Adorjan, I.; Kharchenko, P. V.; Khodosevich, K.
10.1101/2020.11.17.386458 — neuroscience — Posted on 2020-11-19
1502 Temporal dynamics of implicit memory underlying serial dependence
Bilacchi, C. M.; Sirius, E. V. P.; Cravo, A. M.; de Azevedo Neto, R. M.
10.1101/2020.11.17.386821 — neuroscience — Posted on 2020-11-19
1503 Targeted memory reactivation of a serial reaction time task in SWS, but not REM, preferentially benefits the non-dominant hand
Koopman, A. C. M.; Abdellahi, M. E. A.; Belal, S.; Rakowska, M.; Metcalf, A.; Sledziowska, M.; Hunter, T.; Lewis, P.
10.1101/2020.11.17.381913 — neuroscience — Posted on 2020-11-19
1514 Magnaporthe oryzae populations in Sub-Saharan Africa are diverse and show signs of local adaptation
Onaga, G.; Suktrakul, W.; Wanjiku, M.; Quibod, I. L.; Domelevo Entfellner, J.-B.; Bigirimana, J.; Habarugira, G.; Murori, R.; Asea, G.; Ismail, A. M.; Jantasuriyarat, C.; Oliva, R.
10.1101/2020.11.17.377325 — genomics — Posted on 2020-11-19
1517 Transgenerational Regulation of Sexual Attractiveness in C. elegans Nematodes
Toker, I. A.; Lev, I.; Mor, Y.; Gurevich, Y.; Fisher, D.; Houri-Zeevi, L.; Antonova, O.; Hadany, L.; Shaham, S.; Rechavi, O.
10.1101/2020.11.18.389387 — molecular biology — Posted on 2020-11-19
1518 A Low-Cost Mass Spectrometry-Based Approach for Quantifying Purines in Placental Extracts
Rodriguez, R.; Konovets, I.; Ralchenko, S.; Kharkhota, M.; Kostyuk, A.; Kosach, V.; Voronina, I.; Filimonova, N.; Obolenskaya, M. Y.
10.1101/2020.11.19.389817 — molecular biology — Posted on 2020-11-19
1519 Microbial Metagenomic Approach Uncovers the First Rabbit Haemorrhagic Disease Virus genome in Sub-Saharan Africa
Happi, A. N.; Ogunsanya, O. A.; Oguzie, J.; Oluniyi, P. E.; Olono, A. S.; Heeney, J. L.; Happi, C.
10.1101/2020.11.19.390559 — molecular biology — Posted on 2020-11-19
1522 Tobramycin adaptation enhances policing of social cheaters in Pseudomonas aeruginosa
Abisado, R.; Kimbrough, J. H.; McKee, B. M.; Craddock, V.; Smalley, N. E.; Dandekar, A. A.; Chandler, J. R.
10.1101/2020.11.15.383836 — microbiology — Posted on 2020-11-19
1523 Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance
Fareh, M.; Zhao, W.; Hu, W.; Casan, J. M.; Kumar, A.; Symons, J.; Voskoboinik, I.; Ekert, P. G.; Rudraraju, R.; Lewin, S. R.; Trapani, J. A.
10.1101/2020.11.18.389312 — microbiology — Posted on 2020-11-19
1524 Asymmetric outcome of community coalescence of seed and soil microbiota during early seedling growth
Sarniguet, A.; Rochefort, A.; Simonin, M.; Marais, C.; Guillerm-Erckelboudt, A.-Y.; Barret, M.
10.1101/2020.11.19.390344 — microbiology — Posted on 2020-11-19
1526 HTT silencing delays onset and slows progression of Huntington disease like phenotype: Monitoring with a novel neurovascular biomarker
Liu, H.; Zhang, C.; Xu, J.; Jin, J.; Cheng, l.; Wu, Q.; Wei, Z.; Liu, P.; Lu, H.; van Zijl, P.; Ross, C. A.; Hua, J.; Duan, W.
10.1101/2020.11.17.386631 — neuroscience — Posted on 2020-11-19
1527 Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons
Lesnikova, A.; Casarotto, P. C.; Fred, M. S.; Voipio, M.; Winkel, F.; Steinzeig, A.; Antila, H.; Umemori, J.; Biojone, C.; Castren, E.
10.1101/2020.08.13.249615 — neuroscience — Posted on 2020-11-19
1528 Inhibition of VCP preserves retinal structure and function in autosomal dominant retinal degeneration
Arango-Gonzalez, B.; Sen, M.; Guarascio, R.; Ziaka, K.; del Amo, E. M.; Hau, K.; Poultney, H.; Asfahani, R.; Urtti, A.; Chou, T.-F.; Bolz, S.; Deshaies, R. J.; Haq, W.; Cheetham, M. E.; Ueffing, M.
10.1101/2020.11.17.384669 — neuroscience — Posted on 2020-11-19
1530 Sex-specific classification of drug-induced Torsade de Pointes susceptibility using cardiac simulations and machine learning
Fogli Iseppe, A.; Ni, H.; Zhu, S.; Zhang, X.; Coppini, R.; Yang, P.-C.; Srivatsa, U.; Clancy, C. E.; Edwards, A. G.; Morotti, S.; Grandi, E.
10.1101/2020.10.26.352740 — pharmacology and toxicology — Posted on 2020-11-19
1532 Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis
Rychkov, D.; Neely, J.; Oskotsky, T.; Yu, S.; Perlmutter, N.; Nititham, J.; Carvidi, A.; Krueger, M.; Gross, A. J.; Criswell, L. A.; Ashouri, J. F.; Sirota, M.
10.1101/2020.07.24.220483 — bioinformatics — Posted on 2020-11-19
1533 precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions
Olson, N. D.; Wagner, J.; McDaniel, J.; Stephens, S. H.; Westreich, S. T.; Prasanna, A. G.; Johanson, E.; Boja, E.; Maier, E. J.; Serang, O.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Kyriakidis, K.; Malousi, A.; Shafin, K.; Pesout, T.; Jain, M.; Paten, B.; Chang, P.-C.; Kolesnikov, A.; Nattestad, M.; Baid, G.; Goel, S.; Yang, H.; Carroll, A.; Eveleigh, R.; Bourgey, M.; Bourque, G.; Li, G.; MA, C.; Tang, L.; DU, Y.; Zhang, S.; Morata, J.; Tonda, R.; Parra, G.; Trotta, J.-R.; Brueffer, C.; Demirkaya-Budak, S.; Kabakci-Zorlu, D.; Turgut, D.; Kalay
10.1101/2020.11.13.380741 — bioinformatics — Posted on 2020-11-19
1535 Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse neocortex
Liang, L.; Fazel Darbandi, S.; Pochareddy, S.; Gulden, F. O.; Gilson, M. C.; Sheppard, B. K.; Sahagun, A.; An, J.-Y.; Werling, D. M.; Rubenstein, J. L. R.; Sestan, N.; Bender, K.; Sanders, S. J.
10.1101/2020.11.18.389171 — genetics — Posted on 2020-11-19
1538 VTAM: A robust pipeline for validating metabarcoding data using internal controls
Gonzalez, A.; Dubut, V.; Corse, E.; Mekdad, R.; Dechatre, T.; Meglecz, E.
10.1101/2020.11.06.371187 — ecology — Posted on 2020-11-19
1542 Loss of integration of brain networks after sleep deprivation relates to the worsening of cognitive functions
Pesoli, M.; Rucco, R.; Liparoti, M.; Lardone, A.; D'Aurizio, G.; Minino, R.; Troisi Lopez, E.; Paccone, A.; Granata, C.; Mandolesi, L.; Sorrentino, G.; Sorrentino, P.
10.1101/2020.07.15.197590 — neuroscience — Posted on 2020-11-19
1543 Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington's disease
Casale, A. M.; Liguori, F.; Ansaloni, F.; Cappucci, U.; Finaurini, S.; Spirito, G.; Persichetti, F.; Sanges, R.; Gustincich, S.; Piacentini, L.
10.1101/2020.11.19.389718 — neuroscience — Posted on 2020-11-19
1544 Epitomic analysis of the specificity of conformation-dependent, anti-aβ amyloid monoclonal antibodies
Reyes-Ruiz, J. M.; Nakajima, R.; Baghallab, I.; Goldschmidt, L.; Sosna, J.; Ho, P. N. M.; Kumosani, T.; Felgner, P. L.; Glabe, C. G.
10.1101/2020.08.05.238105 — neuroscience — Posted on 2020-11-19
1546 Natural deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
McCarthy, K. R.; Rennick, L. J.; Nambulli, S.; Robinson-McCarthy, L. R.; Bain, W. G.; Haidar, G.; Duprex, W. P.
10.1101/2020.11.19.389916 — microbiology — Posted on 2020-11-19
1547 SARS-CoV-2 infection suppresses ACE2 function and antiviral immune response in the upper respiratory tract of infected patients
Gutierrez-Chamorro, L.; Riveira-Munoz, E.; Barrios, C.; Palau, V.; Massanella, M.; Garcia-Vidal, E.; Badia, R.; Pedreno, S.; Senserrich, J.; Rodriguez, E.; Clotet, B.; Cabrera, C.; Mitja, O.; Crespo, M.; Pascual, J.; Riera, M.; Ballana, E.
10.1101/2020.11.18.388850 — immunology — Posted on 2020-11-19
1549 Common allotypes of ER aminopeptidase 1 have substrate- dependent and highly variable enzymatic properties
Jonathan, H. P.; Temponeras, I.; Kuiper, J.; Cortes, A.; Korczynska, J.; Kitchen, S.; Stratikos, E.
10.1101/2020.11.19.389403 — biochemistry — Posted on 2020-11-19
1550 Extracellular vesicles from human adipose stem cells are neuroprotective after stroke in rats
Rohden, F.; Teixeira, L. V.; Bernardi, L. P.; Marques, N. P. F.; Colombo, M.; Teixeira, G. R.; de Oliveira, F. d. S.; Cirne Lima, E. O.; Guma, F. C. R.; Souza, D. O.
10.1101/2020.11.18.388355 — biochemistry — Posted on 2020-11-19
1551 Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection
Liu, Y.; Mukherjee, R.; Bonn, F.; Colby, T.; Matic, I.; Glogger, M.; Heilemann, M.; Dikic, I.
10.1101/2020.07.27.223842 — cell biology — Posted on 2020-11-19
1553 Heritable Sexual Attraction under Parental Control
Toker, I. A.; Lev, I.; Mor, Y.; Gurevich, Y.; Fisher, D.; Houri-Zeevi, L.; Antonova, O.; Hadany, L.; Shaham, S.; Rechavi, O.
10.1101/2020.11.18.389387 — molecular biology — Posted on 2020-11-19
1554 TBPL2/TFIIA complex establishes the maternal transcriptome by an oocyte-specific promoter usage
Yu, C.; Cvetesic, N.; Hisler, V.; Gupta, K.; Ye, T.; Gazdag, E.; Negroni, L.; Hajkova, P.; Berger, I.; Lenhard, B.; Mueller, F.; Vincent, S. D.; Tora, L.
10.1101/2020.06.08.118984 — molecular biology — Posted on 2020-11-19
1556 Ngn2 induces diverse neuronal lineages from human pluripotency
Lin, H.-C.; He, Z.; Ebert, S.; Schörnig, M.; Santel, M.; Weigert, A.; Hevers, W.; Nadif Kasri, N.; Taverna, E.; Camp, J. G.; Treutlein, B.
10.1101/2020.11.19.389445 — neuroscience — Posted on 2020-11-19
1558 Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington's disease
Casale, A. M.; Liguori, F.; Ansaloni, F.; Finaurini, S.; Spirito, G.; Persichetti, F.; Sanges, R.; Gustincich, S.; Piacentini, L.
10.1101/2020.11.19.389718 — neuroscience — Posted on 2020-11-19
1560 Detecting SARS-CoV-2 variants with SNP genotyping
Harper, H.; Burridge, A. J.; Winfield, M.; Finn, A.; Davidson, A. D.; Matthews, D.; Hutchings, S.; Vipond, B.; Jain, N.; Edwards, K. J.; Barker, G.; The COVID-19 Genomics UK (COG-UK) consortium,
10.1101/2020.11.18.388140 — genomics — Posted on 2020-11-19
1561 MLL1 is required for maintenance of intestinal stem cells and the expression of the cell adhesion molecule JAML
Goveas, N.; Waskow, C.; Arndt, K.; Heuberger, J.; Zhang, Q.; Alexopoulou, D.; Dahl, A.; Birchmeier, W.; Anastassiadis, K.; Stewart, A. F.; Kranz, A.
10.1101/2020.11.19.389528 — genetics — Posted on 2020-11-19
1567 Dorsal Periaqueductal gray ensembles represent approach and avoidance states
Reis, F. M.; Lee, J. Y.; Maesta-Pereira, S.; Schuette, P. J.; Chakerian, M.; Liu, J.; La-Vu, M. Q.; Tobias, B. C.; Canteras, N.; Kao, J. C.; Adhikari, A.
10.1101/2020.11.19.389486 — neuroscience — Posted on 2020-11-19
1572 The chemotherapeutic drug methotrexate selects for antibiotic resistance
Guthmundsdottir, J. S.; Fredheim, E. G. A.; Koumans, C. I. M.; Hegstad, J.; Tang, P.-C.; Andersson, D. I.; Samuelsen, O.; Johnsen, P. J.
10.1101/2020.11.12.378059 — microbiology — Posted on 2020-11-19
1573 Visual effort moderates postural cascade dynamics
Mangalam, M.; Lee, I.-C.; Newell, K. M.; Kelty-Stephen, D. G.
10.1101/2020.07.17.209486 — neuroscience — Posted on 2020-11-19
1584 Structural Basis of Complex Formation Between Mitochondrial Anion Channel VDAC1 and Hexokinase-II
Haloi, N.; Wen, P.-C.; Cheng, Q.; Yang, M.; Natarajan, G.; Camara, A. K. S.; Kwok, W.-M.; Tajkhorshid, E.
10.1101/2020.11.18.365965 — biophysics — Posted on 2020-11-18
1585 Cell-to-cell heterogeneity in Sox2 and Brachyury expression guides progenitor destiny by controllingtheir movements.
Romanos, M.; Allio, G.; Combres, L.; Medevielle, F.; Escalas, N.; Soula, C.; Steventon, B.; Trescases, A.; Benazeraf, B.
10.1101/2020.11.18.388611 — developmental biology — Posted on 2020-11-18
1586 The centriolar satellite protein Cfap53/Ccdc11 facilitates the formation of the first zygotic microtubule organizing center in the zebrafish embryo.
Willekers, S.; Tessadori, F.; Vaart, B. v. d.; Henning, H. H. W.; Stucchi, R.; Altelaar, M.; Roelen, B. A. J.; Akhmanova, A.; Bakkers, J.
10.1101/2020.11.18.388652 — developmental biology — Posted on 2020-11-18
1587 The multi-scale architecture of mammalian sperm flagella and implications for ciliary motility
Leung, M. R.; Roelofs, M. C.; Ravi, R. T.; Maitan, P.; Henning, H.; Zhang, M.; Bromfield, E. G.; Howes, S. C.; Gadella, B. M.; Gadelha, H.; Zeev-Ben-Mordehai, T.
10.1101/2020.11.18.388975 — cell biology — Posted on 2020-11-18
1588 Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold
Schweizer, N.; Haren, L.; Viais, R.; Lacasa, C.; Dutto, I.; Merdes, A.; Luders, J.
10.1101/2020.11.18.384156 — cell biology — Posted on 2020-11-18
1589 High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism
Parlakgul, G.; Arruda, A. P.; Cagampan, E.; Pang, S.; Guney, E.; Lee, Y.; Hess, H. F.; Xu, C. S.; Hotamisligil, G. S.
10.1101/2020.11.18.387803 — cell biology — Posted on 2020-11-18
1590 Biomarkers of lesion severity in a rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION)
Guo, Y.; Mehabian, Z.; Johnson, M. A.; Miller, N. R.; Henderson, A.; Hamlyn, J.; Bernstein, S. L.
10.1101/2020.11.18.388132 — neuroscience — Posted on 2020-11-18
1591 Polygenic transcriptome risk scores improve portability of polygenic risk scores across ancestries
Liang, Y.; Pividori, M.; Manichaikul, A.; Palmer, A. A.; Cox, N. J.; Wheeler, H. E.; Im, H. K.
10.1101/2020.11.12.373647 — genetics — Posted on 2020-11-18
1592 Reducing error and increasing reliability of wildlife counts from citizen science surveys: counting Weddell Seals in the Ross Sea from satellite images
Salas, L.; LaRue, M.; Nur, N.; Ainley, D.; Stammerjohn, S.; Pennycook, J.; Rotella, J.; Paterson, J. T.; Siniff, D.; Stamatiou, K.; Dozier, M.; Saints, J.; Barrington, L.
10.1101/2020.11.18.388157 — ecology — Posted on 2020-11-18
1593 Dysglycemia is associated with Mycobacterium tuberculosis lineages in tuberculosis patients of North Lima - Peru.
Lopez, K.; Arriaga, M. B.; Aliaga, J. G.; Barreda, N. N.; Sanabria, O. M.; Huang, C.-C.; Zhang, Z.; Garcia-de-la-Guarda, R.; Lecca, L.; Calcada Carvalho, A. C.; Kritski, A. L.; Calderon, R. I.
10.1101/2020.11.18.388124 — molecular biology — Posted on 2020-11-18
1594 A comprehensive map of genetic interactions in childhood cancer reveals multiple underlying biological mechanisms
Daub, J. T.; Amini, S.; Kersjes, D. J. E.; Ma, X.; Jäger, N.; Zang, J.; Pfister, S. M.; Holstege, F. C. P.; Kemmeren, P.
10.1101/2020.11.17.385120 — cancer biology — Posted on 2020-11-18
1596 Role of FMRP in rapid antidepressant effects and synapse regulation
Heaney, C. F.; Namjoshi, S. V.; Uneri, A.; Bach, E. C.; Weiner, J. L.; Raab-Graham, K. F.
10.1101/2020.08.25.266833 — molecular biology — Posted on 2020-11-18
1598 γ-secretase promotes postsynaptic maturation through the cleavage of a Wnt receptor
Restrepo, L.; DePew, A.; Moese, E.; Tymanskyj, S.; Parisi, M.; Aimino, M.; Duhart, J. C.; Fei, H.; Mosca, T. J.
10.1101/2020.11.18.387720 — neuroscience — Posted on 2020-11-18
1601 Transient genomic instability drives tumorigenesis through accelerated clonal evolution
Shoshani, O.; Bakker, B.; Wang, Y.; Kim, D. H.; Maldonado, M.; Demarest, M. A.; Artates, J.; Zhengyu, O.; Mark, A.; Wardenaar, R.; Sasik, R.; Spierings, D. C.; Vitre, B.; Fisch, K.; Foijer, F.; Cleveland, D. W.
10.1101/2020.11.17.387753 — cancer biology — Posted on 2020-11-18
1602 Methionine stress induces a ferroptotic gene signature in methionine dependent cancer cells
Wallis, K. F.; Bird, J. T.; Gies, A. J.; Mackintosh, S. G.; Tackett, A. J.; Byrum, S.; Miousse, I. R.
10.1101/2020.08.18.254490 — cancer biology — Posted on 2020-11-18
1603 CPEB2 m6A Methylation Regulates BTB Permeability via Affecting Splicing Factor SRSF5 Stability
zhang, m.; yang, c.; liu, x.; ruan, x.; wang, d.; liu, y.; cai, h.; zheng, j.; shao, l.; wang, p.; li, z.; yu, b.; XUE, Y.
10.1101/2020.11.17.387928 — cancer biology — Posted on 2020-11-18
1604 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-18
1606 Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse neocortex
Liang, L.; Fazel Darbandi, S.; Pochareddy, S.; Gulden, F. O.; Gilson, M. C.; Sheppard, B. K.; Sahagun, A.; An, J.-Y.; Werling, D. M.; Rubenstein, J. L. R.; Sestan, N.; Bender, K.; Sanders, S. J.
10.1101/2020.11.18.389171 — genetics — Posted on 2020-11-18
1610 Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 in vitro
Le-Trilling, V. T. K.; Mennerich, D.; Schuler, C.; Flores-Martinez, Y.; Katschinski, B.; Dittmer, U.; Trilling, M.
10.1101/2020.11.18.388710 — microbiology — Posted on 2020-11-18
1611 Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B
Mansfield, M. J.; Tremblay, B. J.-M.; Zeng, J.; Wei, X.; Hodgins, H.; Worley, J.; Bry, L.; Dong, M.; Doxey, A. C.
10.1101/2020.07.09.194449 — microbiology — Posted on 2020-11-18
1612 The ChiS family DNA-binding domain contains a cryptic helix-turn-helix variant
Klancher, C. A.; Minasov, G.; Podicheti, R.; Rusch, D. B.; Dalia, T. N.; Satchell, K. J.; Neiditch, M. B.; Dalia, A. B.
10.1101/2020.11.18.389122 — microbiology — Posted on 2020-11-18
1613 COVID-19-associated olfactory dysfunction reveals SARS-CoV-2 neuroinvasion and persistence in the olfactory system
De Melo, G. D.; Lazarini, F.; Levallois, S.; Hautefort, C.; Michel, V.; Larrous, F.; Verillaud, B.; Aparicio, C.; Wagner, S.; Gheusi, G.; Kergoat, L.; Kornobis, E.; Cokelaer, T.; Hervochon, R.; Madec, Y.; Roze, E.; Salmon, D.; Bourhy, H.; Lecuit, M.; Lledo, P.-M.
10.1101/2020.11.18.388819 — neuroscience — Posted on 2020-11-18
1614 Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.
Cox, S. R.; Harris, M. A.; Ritchie, S. J.; Buchanan, C. R.; Valdes Hernandez, M. d. C.; Corley, J.; Taylor, A. M.; Madole, J. W.; Harris, S. E.; Whalley, H. C.; McIntosh, A. M.; Russ, T. C.; Bastin, M. E.; Wardlaw, J. M.; Deary, I. J.; Tucker-Drob, E. M.
10.1101/2020.01.19.911420 — neuroscience — Posted on 2020-11-18
1615 Photostimulation of lymphatic clearance of red blood cells from the mouse brain after intraventricular hemorrhage
Li, D.; Liu, S.; Yu, T.; Liu, Z.; Sun, S.; Bragin, D.; Navolokin, N.; Kurths, J.; Semyachkina-Glushkovskaya, O. V.; Zhu, D.
10.1101/2020.11.16.384149 — neuroscience — Posted on 2020-11-18
1617 Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders
Kaul, D.; Smith, C. C.; Stevens, J.; Frohlich, A. S.; Binder, E. B.; Mechawar, N.; Schwab, S. G.; Matosin, N.
10.1101/2020.08.31.276386 — neuroscience — Posted on 2020-11-18
1618 A genetic screen identifies dreammist as a regulator of sleep
Barlow, I. L.; Mackay, E.; Wheater, E.; Goel, A.; Lim, S.; Zimmerman, S.; Woods, I.; Prober, D. A.; Rihel, J.
10.1101/2020.11.18.388736 — neuroscience — Posted on 2020-11-18
1621 A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience
Santos, J. P. G.; Pajo, K.; Trpevski, D.; Stepaniuk, A.; Eriksson, O.; Nair, A. G.; Keller, D.; Hellgren Kotaleski, J.; Kramer, A.
10.1101/2020.11.17.385203 — systems biology — Posted on 2020-11-18
1623 A Hybrid Cellular and Heterogeneous Catalyst Strategy for the Production of Olefins from Glucose
Wang, Z. Q.; Song, H.; Hara, N.; Park, D. S.; Kumar, G.; Min, Y.; Dauenhauer, P. J.; Chang, M. C. Y.
10.1101/2020.11.17.387563 — synthetic biology — Posted on 2020-11-18
1624 Transcriptome atlas of Phalaenopsis equestris
Klepikova, A. V.; Kasianov, A. S.; Ezhova, M. A.; Penin, A. A.; Logacheva, M. D.
10.1101/2020.11.03.366260 — plant biology — Posted on 2020-11-18
1627 Structural basis of ligand selectivity by a bacterial adhesin lectin involved in multi- species biofilm formation
Guo, S.; Vance, T.; Zahiri, H.; Eves, R.; Stevens, C.; Hehemann, J.-H.; Vidal-Melgosa, S.; Davies, P.
10.1101/2020.11.18.389155 — biochemistry — Posted on 2020-11-18
1628 Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains
Bersaglieri, C.; Kresoja-Rakic, J.; Gupta, S.; Baer, D.; Kuzyakiv, R.; Santoro, R.
10.1101/2020.11.17.386797 — genomics — Posted on 2020-11-18
1631 Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a novel peptide-binding domain
Guo, S.; Zahiri, H.; Stevens, C.; Spaanderman, D.; Milroy, L.-G.; Ottmann, C.; Brunsveld, L.; Voets, I.; Davies, P.
10.1101/2020.11.18.389114 — microbiology — Posted on 2020-11-18
1632 Modeling Side-Stream Enhanced Biological Phosphorus Removal (S2EBPR) System Using Agent-based Model with Adaptive Maintenance, Decay and TCA Metabolism
Li, G.; Tooker, N. B.; Wang, D.; Srinivasan, V.; Barnard, J. L.; Russel, A.; Takacs, I.; Bott, C.; Dobrowski, P.; Onnis-Hayden, A.; Gu, A. Z.
10.1101/2020.11.18.387589 — microbiology — Posted on 2020-11-18
1634 Heme is crucial for medium-dependent metronidazole resistance in clinical isolates of C. difficile
Boekhoud, I. M.; Sidorov, I.; Nooij, S.; Harmanus, C.; Bos-Sanders, I. M. J. G.; Viprey, V.; Spittal, B.; Clark, E.; Davies, K.; Freeman, J.; Kuijper, E. J.; Smits, W. K.; COMBACTE-CDI Consortium, ; European Study Group for Clostridioides difficile,
10.1101/2020.11.18.388959 — microbiology — Posted on 2020-11-18
1637 Unifying the global coding sequence space enables the study of genes with unknown function across biomes
Vanni, C.; Schechter, M. S.; Acinas, S.; Barberan, A.; Buttigieg, P. L.; Casamayor, E. O.; Delmont, T. O.; Duarte, C. M.; Eren, A. M.; Finn, R. D.; Kottmann, R.; Mitchell, A.; Sanchez, P.; Siren, K.; Steinegger, M.; Glöckner, F. O.; Fernandez-Guerra, A.
10.1101/2020.06.30.180448 — microbiology — Posted on 2020-11-18
1638 The expression of PDCD1 and CD274 in T cells and macrophages correlated positively with COVID-19 severity
Gao, Q.; Liu, S.; Ding, R.; Chen, H.; Dong, X.; Xie, J.; Li, Y.; Chen, L.; Liu, H.; Mu, F.
10.1101/2020.11.17.378992 — immunology — Posted on 2020-11-18
1643 Rational Design and Synthesis of Selective PRMT4 Inhibitors: a New Chemotype for Development of Cancer Therapeutics
Sutherland, M.; Li, A.; Kaghad, A.; Panagopoulos, D.; Li, F.; Szewczyk, M.; Smil, D.; Scholten, C.; Bouche, L.; Stellfeld, T.; Arrowsmith, C.; Barsyte, D.; Vedadi, M.; Hartung, I. V.; Steuber, H.; Britton, R.; Santhakumar, V.
10.1101/2020.11.17.387233 — pharmacology and toxicology — Posted on 2020-11-18
1644 Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi and Heligmosomoides polygyrus
Partridge, F. A.; Bataille, C. J.; Forman, R.; Marriott, A. E.; Häberli, C.; Dinsdale, R. L.; O'Sullivan, J. D.; Willis, N.; Archer, J.; Steven, A.; Taylor, M. J.; Keiser, J.; Turner, J. D.; Else, K. J.; Russell, A. J.; Sattelle, D. B.
10.1101/2020.11.17.384933 — pharmacology and toxicology — Posted on 2020-11-18
1646 LFMD: detecting low-frequency mutations in high-depth genome sequencing data without molecular tags
Ye, R.; Zhuang, X.; Ruan, J.; Qi, Y.; An, Y.; Xu, J.; Mak, T.; Liu, X.; Zhang, X.; Yang, H.; Xu, X.; Baum, L.; Nie, C.; Sham, P. C.
10.1101/617381 — bioinformatics — Posted on 2020-11-18
1647 Shape and size complementarity induced formation of supramolecular protein assemblies with metal-oxo clusters
Vandebroek, L.; Noguchi, H.; Kamata, K.; Tame, J. R. H.; Van Meervelt, L.; Parac-Vogt, T. N.; Voet, A. R. D.
10.1101/2020.11.18.388215 — biochemistry — Posted on 2020-11-18
1649 A unique adhesive motif of protein disulfide isomerase P5 supports its function via dimerization
Okumura, M.; Kanemura, S.; Matsusaki, M.; Kinoshita, M.; Saio, T.; Ito, D.; Hirayama, C.; Kumeta, H.; Watabe, M.; Amagai, Y.; Lee, Y.-H.; Akiyama, S.; Inaba, K.
10.1101/2020.11.17.387910 — biochemistry — Posted on 2020-11-18
1651 Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation.
Ulferts, R.; Marcassa, E.; Timimi, L.; Lee, L. C.; Daley, A.; Montaner, B.; Turner, S. D.; Florey, O.; Baillie, J. K.; Beale, R.
10.1101/2020.11.18.388306 — cell biology — Posted on 2020-11-18
1653 An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccines
Quinlan, B. D.; Li, W.; Mou, H.; Zhang, L.; Chang, J.; Peng, S.; Ojha, A.; Tavora, R.; Parcells, M. S.; Luo, G. G.; Li, W.; Zhong, G.; Choe, H.; Farzan, M.
10.1101/2020.11.18.388934 — microbiology — Posted on 2020-11-18
1655 Human fecal microbiota is associated with colorectal cancer
Yao, Q.; Tang, M.; Zeng, L.; Chu, Z.; Sheng, H.; Zhang, Y.; Zhou, Y.; Zhang, H.; Jiang, H.; Ye, M.
10.1101/2020.11.17.387647 — microbiology — Posted on 2020-11-18
1656 The human cytomegalovirus protein UL116 interacts with the viral ER resident glycoprotein UL148 and promotes the incorporation of gH/gL complexes into virions
Siddiquey, M. N. A.; Schultz, E. P.; Yu, Q.; Amendola, D.; Vezzani, G.; yu, d.; Maione, D.; Lanchy, J.-M.; Ryckman, B. J.; Merola, M.; Kamil, J. P.
10.1101/2020.11.17.387944 — microbiology — Posted on 2020-11-18
1657 A wide-ranging Pseudomonas aeruginosa PeptideAtlas build: a useful proteomic resource for a versatile pathogen.
Reales-Calderon, J. A.; Sun, Z.; Mascaraque, V.; Perez-Navarro, E.; Vialas, V.; Deutsch, E. W.; Moritz, R. L.; Gil, C.; Martinez, J. L.; Molero, G.
10.1101/2020.11.18.386490 — microbiology — Posted on 2020-11-18
1659 The human cytomegalovirus UL116 glycoprotein is a chaperone to control gH-based complexes levels on virions
Vezzani, G.; Amendola, D.; Yu, D.; Chandramouli, S.; Frigimelica, E.; Maione, D.; Merola, M.
10.1101/2020.11.18.387126 — microbiology — Posted on 2020-11-18
1660 Production of anti-SARS-CoV-2 hyperimmune globulin from convalescent plasma
Vandeberg, P.; Cruz, M.; Diez, J. M.; Merritt, W. K.; Santos, B.; Trukawinski, S.; Wellhouse, A.; Jose, M.; Willis, T.
10.1101/2020.11.18.388991 — immunology — Posted on 2020-11-18
1663 Depth-discrete metagenomics reveals the roles of microbes in biogeochemical cycling in the tropical freshwater Lake Tanganyika
Tran, P. Q.; Bachand, S. C.; McIntyre, P. B.; Kraemer, B. M.; Vadeboncoeur, Y.; Kimirei, I. A.; Tamatamah, R.; McMahon, K. D.; Anantharaman, K.
10.1101/834861 — microbiology — Posted on 2020-11-18
1665 Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration
Vidal, R. L.; Sepulveda, D.; Troncoso-Escudero, P.; Garcia-Huerta, P.; Gonzalez, C.; Plate, L.; Jerez, C.; Canovas, J.; Rivera, C.; Castillo, V.; Cisternas, M.; Leal, S.; Martinez, A.; Grandjean, J.; Lashuel, H.; Martin, A. J. M.; Latapiat, V.; Matus, S.; Sardi, S. P.; Wiseman, L.; Hetz, C.
10.1101/2020.11.17.387480 — neuroscience — Posted on 2020-11-18
1671 Long-chain polyphosphates impair SARS-CoV-2 infection and replication: a route for therapy in man
Ferrucci, V.; Dae, Y. K.; Asadzadeh, F.; Marrone, L.; Siciliano, R.; Cerino, P.; Criscuolo, G.; Pisano, I.; Quarantelli, F.; Izzo, B.; Fusco, G.; Comegna, M.; Boccia, A.; Viscardi, M.; Borriello, G.; Brandi, S.; Pierri, B. M.; Tiberio, C.; Atripaldi, L.; Paolella, G.; Castaldo, G.; Pascarella, S.; Bianchi, M.; Della Monica, R.; Chiariotti, L.; Yun, K. S.; Cheong, J. H.; Kim, H. Y.; Zollo, M.
10.1101/2020.11.18.388413 — genetics — Posted on 2020-11-18
1673 An assessment of efficacy of Iodine complex (Renessans) against SARS-CoV-2 in non-human primates (Rhesus macaque)
Nawaz, M.; Ali, M. A.; Ashraf, M. A.; Shabbir, M. Z.; Shabbir, M. A. B.; Altaf, I.; Raza, S.; Rafique, S.; Hassan, S.; Sardar, N.; Mehmood, A.; Aziz, M. W.; Fazal, S.; Khan, M. T.; Atique, M. M.; Asif, A.; Ullah, Z.; Iqbal, M.; Imtiaz, T.; Anwar, M.; Mukhtar, N.; Yaqub, T.
10.1101/2020.11.17.377432 — microbiology — Posted on 2020-11-18
1676 Single-cell Transcriptome of Bronchoalveolar Lavage Fluid Reveals Dynamic Change of Macrophages During SARS-CoV-2 Infection in Ferrets
Lee, J. S.; Koh, J.-Y.; Yi, K.; Kim, Y.-I.; Park, S.-J.; Kim, E.-H.; Kim, S.-M.; Park, S. H.; Ju, Y. S.; Choi, Y. K.; Park, S.-H.
10.1101/2020.11.18.388280 — immunology — Posted on 2020-11-18
1677 High-dimensional association detection in large scale genomic data
Koch, H.; Keller, C. A.; Giardine, B.; Xiang, G.; Zhang, F.; Wang, Y.; Hardison, R. C.; Li, Q.
10.1101/2020.11.18.388504 — bioinformatics — Posted on 2020-11-18
1678 Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays
Mehalko, J.; Drew, M.; Snead, K.; Denson, J.-P.; Wall, V.; Taylor, T.; Sadtler, K.; Messing, S.; Gillette, W.; Esposito, D.
10.1101/2020.11.18.388868 — biochemistry — Posted on 2020-11-18
1679 Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes
Chiem, K.; Morales Vasquez, D.; Park, J.-G.; Platt, R. N.; Anderson, T.; Walter, M. R.; Kobie, J. J.; Ye, C.; Martinez-Sobrido, L.
10.1101/2020.11.16.386003 — microbiology — Posted on 2020-11-18
1680 Activation of the Integrated Stress Response in drug-tolerant melanoma cells confers vulnerability to mitoribosome-targeting antibiotics.
Vendramin, R.; Konnova, A.; Adnane, S.; Cinque, S.; Katopodi, V.; Knezevic, Z.; Karras, P.; Demesmaeker, E.; Bosisio, F. M.; Rizzotto, L.; Bechter, O.; Marine, J.-C.; Leucci, E.
10.1101/2020.06.26.173492 — cancer biology — Posted on 2020-11-18
1681 WEVar: a novel statistical learning framework for predicting noncoding regulatory variants
Chen, L.; Jiang, Y.; Yao, B.; Huang, K.; Liu, Y.; Wang, Y.; Qin, X.; Saykin, A. J.; Wang, Y.
10.1101/2020.11.16.385633 — bioinformatics — Posted on 2020-11-18
1684 Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
Pocaterra, A.; Ament, C.; Ribbak, S.; Evert, M.; Chen, X.; Calvisi, D.; Dupont, S.
10.1101/2020.11.18.388397 — cancer biology — Posted on 2020-11-18
1686 Biochemical and Biophysical Characterization of the dsDNA packaging motor from the Lactococcus lactis bacteriophage asccphi28
Reyes-Aldrete, E.; Dill, E.; Bussetta, C.; Szymanski, M. R.; Diemer, G. S.; Maindola, P.; White, M.; Choi, K.; Morais, M.
10.1101/2020.11.17.383745 — biophysics — Posted on 2020-11-18
1689 DUBStepR: correlation-based feature selection for clustering single-cell RNA sequencing data
Ranjan, B.; Sun, W.; Park, J.; Xie, R.; Alipour, F.; Mishra, K.; Singhal, V.; Prabhakar, S.
10.1101/2020.10.07.330563 — bioinformatics — Posted on 2020-11-18
1691 Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome
Enwerem, I. I. I.; Elrod, N. D.; Chang, C.-T.; Lin, A.; Ji, P.; Bohn, J. A.; Levdansky, Y.; Wagner, E. J.; Valkov, E.; Goldstrohm, A.
10.1101/2020.11.17.387456 — molecular biology — Posted on 2020-11-18
1694 Neuraminidase inhibitors rewire neutrophil function in murine sepsis and COVID-19 patients' cells
Formiga, R. O.; Amaral, F. C.; Souza, C. F.; Mendes, D. A. G. B.; Wanderley, C. W. S.; Lorenzini, C. B.; Santos, A. A.; Antonia, J.; Faria, L. F.; Natale, C. C.; Paula, N. M.; Silva, P. C. S.; Fonseca, F. R.; Aires, L.; Heck, N.; Barroso, S. P. C.; Morrot, A.; Sordi, R.; Alisson-Silva, F.; Mansur, D. S.; Cunha, F. Q.; Maurici, R.; Bafica, A.; Macauley, M. S.; Spiller, F.
10.1101/2020.11.12.379115 — immunology — Posted on 2020-11-18
1696 Freshwater monitoring by nanopore sequencing
Urban, L.; Holzer, A.; Baronas, J. J.; Hall, M.; Braeuninger-Weimer, P.; Scherm, M. J.; Kunz, D. J.; Perera, S. N.; Martin-Herranz, D. E.; Tipper, E. T.; Salter, S. J.; Stammnitz, M. R.
10.1101/2020.02.06.936302 — microbiology — Posted on 2020-11-18
1698 Multiplexed single-cell profiling of chromatin states at genomic loci by expansion microscopy
Woodworth, M. A.; Ng, K. K. H.; Halpern, A. R.; Pease, N. A.; Nguyen, P. H. B.; Kueh, H. Y.; Vaughan, J. C.
10.1101/2020.11.17.385476 — genomics — Posted on 2020-11-18
1702 Genome-wide analysis of long noncoding RNAs, 24-nt siRNAs, DNA methylation and H3K27me3 marks in Brassica rapa and related species
Mehraj, H.; Shea, D. J.; Takahashi, S.; Miyaji, N.; Akter, A.; Seki, M.; Dennis, E. S.; Fujimoto, R.; Osabe, K.
10.1101/2020.11.06.370940 — plant biology — Posted on 2020-11-18
1703 USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-11-18
1705 Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids
Valle-Encinas, E.; Aleksieva, N.; Velasco Martinez, C.; Dawes, M.; Zverev, M.; Muller, M.; Offergeld, A.; Smalley, M. J.; Hogan, C.; Forbes, S. J.; Bird, T. G.; Dale, T. C.
10.1101/2020.11.09.374462 — cell biology — Posted on 2020-11-18
1707 Elephant endotheliotropic herpesvirus is omnipresent in elephants in European zoos and an Asian elephant range country
Hoornweg, T. E.; Schaftenaar, W.; Maurer, G.; van den Doel, P. B.; Molenaar, F. M.; Chamouard-Galante, A.; Vercammen, F.; Rutten, V.; de Haan, C. A. M.
10.1101/2020.11.16.386011 — microbiology — Posted on 2020-11-18
1708 Streptococcus pneumoniae serotypes carried by young children and their association with Acute Otitis Media during the period 2016 - 2019.
Ekinci, E.; Desmet, S.; Van Heirstraeten, L.; Mertens, C.; Wouters, I.; Beutels, P.; Verhaegen, J.; Malhotra-Kumar, S.; Theeten, H.; Npcarriage Study Group, T.
10.1101/2020.11.16.386052 — immunology — Posted on 2020-11-18
1709 Degradation of mixed-linkage (1,3;1,4)-β-D-glucan in maize is mediated by the CAL1 licheninase
Kraemer, F. J.; Lunde, C.; Koch, M.; Kuhn, B. M.; Ruehl, C.; Brown, P.; Hoffmann, P.; Göhre, V.; Hake, S.; Pauly, M.; Ramirez, V.
10.1101/2020.11.16.385146 — plant biology — Posted on 2020-11-18
1714 Deciphering a marine bone degrading microbiome reveals a complex community effort
Borchert, E.; Garcia-Moyano, A.; Sanchez-Carrillo, S.; Dahlgren, T. G.; Slaby, B.; Bjerga, G. E. K.; Ferrer, M.; Franzenburg, S.; Hentschel, U.
10.1101/2020.05.13.093005 — microbiology — Posted on 2020-11-18
1716 GSAP regulates mitochondrial function through the Mitochondria-associated ER membrane in the pathogenesis of Alzheimer's disease
Xu, P.; Chang, J. C.; Zhou, X.; Wang, W.; Bamkole, M.; Wong, E.; Bettayeb, K.; Jiang, L.-L.; Huang, T.; Luo, W.; Xu, H.; Nairn, A. C.; Flajolet, M.; Ip, N.; Li, Y.-M.; Greengard, P.
10.1101/2020.11.17.385245 — neuroscience — Posted on 2020-11-18
1717 Unified neural pathways that gate affective pain and multisensory innate threat signals to the amygdala
Kang, S. J.; Liu, S.; Ye, M.; Kim, D.-I.; Kim, J.-H.; Oh, T. G.; Peng, J.; Evans, R. M.; Lee, K.-F.; Goulding, M.; Han, S.
10.1101/2020.11.17.385104 — neuroscience — Posted on 2020-11-18
1719 The proteomic landscape of resting and activated CD4+ T cells reveal insights into cell differentiation and function
Subbannayya, Y.; Haug, M.; Pinto, S.; Mohanty, V.; Meas, H. Z.; Flo, T. H.; Prasad, T. S. K.; Kandasamy, R. K.
10.1101/2020.11.17.385096 — immunology — Posted on 2020-11-18
1722 USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-11-17
1726 Queuine is a nutritional regulator of Entamoeba histolytica response to oxidative stress and a virulence attenuator
Nagaraja, S.; Cai, M. W.; Sun, J.; Varet, H.; Sarid, L.; Shaulov, Y.; Trebicz-Geffen, M.; Mazumdar, M.; Legendre, R.; Coppee, J.-Y.; Begley, T.; Dedon, P. C.; Gourinath, S.; Guillen, N.; Saito-Nakano, Y.; Shimokawa, C.; Hisaeda, H.; Ankri, S.
10.1101/2020.04.30.070276 — microbiology — Posted on 2020-11-17
1727 Acute social isolation causes midbrain craving responses similar to hunger.
Tomova, L.; Wang, K.; Thompson, T.; Matthews, G.; Takahashi, A.; Tye, K.; Saxe, R.
10.1101/2020.03.25.006643 — neuroscience — Posted on 2020-11-17
1730 KDM2B promotes cell viability by enhancing DNA damage response in canine hemangiosarcoma
Gulay, K. C. M.; Aoshima, K.; Shibata, Y.; Yasui, H.; Yan, Q.; Kobayashi, A.; Kimura, T.
10.1101/2020.11.17.387704 — cancer biology — Posted on 2020-11-17
1731 Transient genomic instability drives tumorigenesis through accelerated clonal evolution
Shoshani, O.; Bakker, B.; Wang, Y.; Kim, D. H.; Maldonado, M.; Demarest, M. A.; Artates, J.; Zhengyu, O.; Mark, A.; Wardenaar, R.; Sasik, R.; Spierings, D. C.; Vitre, B.; Fisch, K.; Foijer, F.; Cleveland, D. W.
10.1101/2020.11.17.387753 — cancer biology — Posted on 2020-11-17
1736 MrvR, a group B Streptococcus transcription factor that controls multiple virulence traits
Dammann, A. N.; Chamby, A. B.; Catomeris, A. J.; Davidson, K. M.; Tettelin, H.; van Pijkeren, J. P.; Gopalakrishna, K. P.; Keith, M. F.; Elder, J. L.; Ratner, A. J.; Hooven, T.
10.1101/2020.11.17.386367 — microbiology — Posted on 2020-11-17
1739 LRP1 and SORL1 regulate tau internalization and degradation and enhance tau seeding
Cooper, J. M.; Lathuiliere, A.; Migliorini, M.; Arai, A. L.; Wani, M. M.; Dujardin, S.; Muratoglu, S. C.; Hyman, B. T.; Strickland, D.
10.1101/2020.11.17.386581 — neuroscience — Posted on 2020-11-17
1743 A plant lipocalin is required for retinal-mediated de novo root organogenesis
Dickinson, A. J.; Zhang, J.; Luciano, M.; Wachsman, G.; Schnermann, M.; Dinneny, J. R.; Benfey, P. N.
10.1101/2020.11.09.375444 — plant biology — Posted on 2020-11-17
1752 Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells
Pae, J.; Ersching, J.; Castro, T. B.; Schips, M.; Mesin, L.; Allon, S. J.; Ordovas-Montanes, J.; Mlynarczyk, C.; Melnick, A.; Efeyan, A.; Shalek, A. K.; Meyer-Hermann, M.; Victora, G. D.
10.1101/2020.11.17.385716 — immunology — Posted on 2020-11-17
1756 NAP-CNB: Bioinformatic pipeline to predict MHC-I-restricted T cell epitopes in mice
Wert-Carvajal, C.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Mendez Perez, A.; Alemany, R.; Veiga, E.; Sorzano, C. O. S.; Munoz-Barrutia, A.
10.1101/2020.10.05.327015 — bioinformatics — Posted on 2020-11-17
1759 Knockout of myoc reveals the role of myocilin in zebrafish sex determination associated with Wnt signalling downregulation
Atienzar-Aroca, R.; Aroca-Aguilar, J.-D.; Alexandre-Moreno, S.; Ferre-Fernández, J.-J.; Juan-Manuel Bonet-Fernández, J.-M.; Cabañero-Varela, M.-J.; Escribano, J.
10.1101/2020.11.17.380147 — genetics — Posted on 2020-11-17
1764 PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts
Piberger, A. L.; Bowry, A.; Kelly, R. D. W.; Walker, A. K.; Gonzalez, D.; Bailey, L. J.; Doherty, A. J.; Mendez, J.; Morris, J. R.; Bryant, H. E.; Petermann, E.
10.1101/773242 — molecular biology — Posted on 2020-11-17
1767 Immunogenicity of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques
Solforosi, L.; Kuipers, H.; Rosendahl Huber, S. K.; van der Lubbe, J. E. M.; Dekking, L.; Czapska-Casey, D. N.; Izquierdo Gil, A.; Baert, M.; Drijver, J.; Vaneman, J.; van Huizen, E.; Choi, Y.; Vreugdenhil, J.; Dalebout, T. J.; Myeni, S. K.; Kikkert, M.; Snijder, E. J.; Barouch, D. H.; Koopman, G.; Mooij, P.; Bogers, W. M. J. M.; Muchene, L.; Tolboom, J. T. B. M.; Roozendaal, R.; Schuitemaker, H.; Wegmann, F.; Zahn, R. C.
10.1101/2020.11.17.368258 — immunology — Posted on 2020-11-17
1768 Rab27 GTPases regulate alpha-synuclein uptake, cell-to-cell 1 transmission, and toxicity
Underwood, R. N.; Wang, B.; Pathak, A.; Volpicelli-Daley, L.; Yacoubian, T. A.
10.1101/2020.11.17.387449 — neuroscience — Posted on 2020-11-17
1770 Palmitoylation Couples DLK to JNK3 to Facilitate Pro-degenerative Axon-to-Soma Signaling
Niu, J.; Holland, S. M.; Ketschek, A.; Collura, K. M.; Hayashi, T.; Smith, G. M.; Gallo, G.; Thomas, G.
10.1101/2020.11.17.387191 — neuroscience — Posted on 2020-11-17
1771 Mathematical modeling of ventilator-induced lung inflammation
Minucci, S. B.; Valentine, M. S.; Kamga Gninzeko, F. J.; Heise, R. L.; Reynolds, A. M.
10.1101/2020.06.03.132258 — systems biology — Posted on 2020-11-17
1772 SBGN Bricks Ontology as a tool to describe recurring concepts in molecular networks
Rougny, A.; Toure, V.; Albanese, J.; Waltemath, D.; Shirshov, D.; Sorokin, A.; Bader, G. D.; Blinov, M. L.; Mazein, A.
10.1101/2020.11.16.369330 — systems biology — Posted on 2020-11-17
1773 Acid sensing ion channel 1a is a key mediator of cardiac ischemia-reperfusion injury
Redd, M.; Scheuer, S.; Saez, N.; Chiu, H.; Gao, L.; Hicks, M.; Villanueva, J.; Cuellar-Partida, G.; Peart, J.; See Hoe, L.; Chen, X.; Sun, Y.; Suen, J.; Hatch, R.; Rollo, B.; Alzubaidi, M.; Maljevic, S.; Qaiffe-Ryan, G. A.; Hudson, J. E.; Porrello, E.; Fraser, J.; Petrou, S.; Reichelt, M.; Thomas, W.; King, G.; MacDonald, P.; Palpant, N.
10.1101/869826 — physiology — Posted on 2020-11-17
1775 Human melanocyte development and melanoma dedifferentiation at single cell resolution
Belote, R. L.; Le, D.; Maynard, A.; Lang, U. E.; Sinclair, A.; Planells-Palop, V.; Baskin, L. S.; Tward, A. D.; Darmanis, S.; Judson-Torres, R. L.
10.1101/2020.05.25.115287 — cancer biology — Posted on 2020-11-17
1776 EphB6 regulates TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells
Zangrossi, M.; Chakravarty, P.; Romani, P.; Ratcliffe, C. D. H.; Hooper, S.; Dori, M.; Forcato, M.; Bicciato, S.; Dupont, S.; Sahai, E.; MONTAGNER, M.
10.1101/2020.11.10.376186 — cancer biology — Posted on 2020-11-17
1778 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-17
1779 Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition
Geuens, T.; Ruiter, F. A. A.; Schumacher, A.; Morgan, F. L. C.; Rademakers, T.; Wiersma, L. E.; van den Berg, C. W.; Rabelink, T. J.; Baker, M. B.; LaPointe, V. L. S.
10.1101/2020.11.17.386250 — bioengineering — Posted on 2020-11-17
1782 UniBind: maps of high-confidence direct TF-DNA interactions across nine species
Riudavets Puig, R.; Boddie, P.; Khan, A.; Castro-Mondragon, J. A.; Mathelier, A.
10.1101/2020.11.17.384578 — genomics — Posted on 2020-11-17
1784 Population structure and transmission of Mycobacterium bovis in Ethiopia
Almaw, G.; Mekonnen, G. A.; Mihret, A.; Aseffa, A.; Taye, H.; Conlan, A. J.; Gumi, B.; Zewude, A.; Aliy, A.; Tamiru, M.; Olani, A.; Lakew, M.; Sombo, M.; Gebre, S.; Diguimbaye, C.; Hilty, M.; Fane, A.; Muller, B.; Hewinson, R. G.; Ellis, R. J.; Nunez-Garcia, J.; Palkopoulou, E.; The ETHICOBOTS consortium, ; Abebe, T.; Ameni, G.; Parkhill, J.; Wood, J. L.; Berg, S.; van Tonder, A. J.
10.1101/2020.11.17.386748 — genomics — Posted on 2020-11-17
1786 Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases
Yang, Y.; Musco, H.; Simpson-Yap, S.; Zhu, Z.; Wang, Y.; Lin, X.; Zhang, J.; Taylor, B.; Gratten, J.; Zhou, Y.
10.1101/2020.11.16.385914 — genetics — Posted on 2020-11-17
1787 Genetic sensitivity analysis: adjusting for genetic confounding in epidemiological associations
Pingault, J.-B.; Rijsdijk, F.; Schoeler, T.; Choi, S. W.; Selzam, S.; Krapohl, E.; O'Reilly, P. F.; Dudbridge, F.
10.1101/592352 — genetics — Posted on 2020-11-17
1788 Inferring Adaptive Introgression Using Hidden Markov Models
Svedberg, J.; Shchur, V.; Reinman, S.; Nielsen, R.; Corbett-Detig, R.
10.1101/2020.08.02.232934 — evolutionary biology — Posted on 2020-11-17
1792 Development of a mass-spectrometry based method for the identification of the in vivo whole blood and plasma ADP-ribosylomes
Luethi, S. C.; Howard, A.; Nowak, K.; Graage, R.; Bartolomei, G.; Neupert, C.; Sidler, X.; Leslie Pedrioli, D. M.; Hottiger, M. O.
10.1101/2020.11.17.384719 — molecular biology — Posted on 2020-11-17
1793 Endothelial exosome plays functional role during rickettsial infection
Liu, Y.; Zhou, C.; Su, Z.; Chang, Q.; Qiu, Y.; Bei, J.; Gaitas, A.; Xiao, J.; Drelich, A.; Khanipov, K.; Jin, Y.; Golovko, G.; Berelli Saito, T.; Gong, B.
10.1101/2020.11.16.385740 — microbiology — Posted on 2020-11-17
1794 The Development of a Novel Nanobody Therapeutic for SARS-CoV-2
Ye, G.; Gallant, J.; Massey, C.; Shi, K.; Tai, W.; Zheng, J.; Odle, A.; Vickers, M.; Shang, J.; Wan, Y.; Drelich, A.; Kempaiah, K.; Tat, V.; Perlman, S.; Du, L.; Tseng, C.-T.; Aihara, H.; LeBeau, A.; Li, F.
10.1101/2020.11.17.386532 — microbiology — Posted on 2020-11-17
1795 Microbiomes attached to fresh perennial ryegrass- are temporally resilient and adapt to changing ecological niches
Huws, S.; Edwards, J.; Lin, W.; Rubino, F.; Alston, M.; Swarbeck, D.; Caim, s.; Rees Stevens, P.; Pachebat, J.; Won, M.-Y.; Oyama, L.; Creevey, C.; KIngston-Smith, A.
10.1101/2020.11.17.386292 — microbiology — Posted on 2020-11-17
1796 A LAMP-based microfluidic chip for rapid detection of pathogen in Cryptococcal meningitis
Guan, M.; Sui, G.; Tian, Y. r.; Zhang, T.; Guo, J.; Lu, H.; Yao, Y.; Chen, X.; Zhang, X.
10.1101/2020.11.16.386045 — microbiology — Posted on 2020-11-17
1797 Revealing interspecies transmission barriers of avian influenza A viruses
Naguib, M. M.; Eriksson, P.; Jax, E.; Nilsson, J.; Sihlbom, C.; Lindskog, C.; Brojer, C.; Olsson, B.-M.; Wille, M.; Waldenstroem, J.; Larson, G.; Kraus, R. H. S.; Lundkvist, A.; Olsen, B.; Jarhult, J. D.; Ellstrom, P.
10.1101/2020.11.17.386755 — microbiology — Posted on 2020-11-17
1798 The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2
Li, P.; Guo, R.; Liu, Y.; Zhang, Y.; Hu, J.; Ou, X.; Mi, D.; Zhang, L.; wang, x.; Wu, Z.; Wang, J.; Jin, Q.; Qian, Z.
10.1101/2020.11.16.385849 — microbiology — Posted on 2020-11-17
1799 Enzyme specific isotope effects of the Nap and Nar nitrate reductases
Asamoto, C. K.; Rempfert, K. R.; Luu, V. H.; Younkin, A. D.; Kopf, S. H.
10.1101/2020.11.17.386888 — microbiology — Posted on 2020-11-17
1800 Universal antimicrobial resistance detection from clinical bacterial isolates using proteomics
Blumenscheit, C.; Pfeifer, Y.; Werner, G.; John, C.; Andy, S.; Lasch, P.; Joerg, D.
10.1101/2020.11.17.386540 — microbiology — Posted on 2020-11-17
1801 Small-molecule antibiotic inhibitors of post-translational protein secretion
Economou, A.; Burchacka, E.; Angus, L.; Marchand, A.; Hamed, M. B.; De Geyter, J.; Loos, M. S.; Anne, J.; Klaassen, H.; Chaltin, P.; Karamanou, S.
10.1101/2020.11.17.387027 — microbiology — Posted on 2020-11-17
1802 An Integrated Workflow for Enhanced Taxonomic and Functional Coverage of the Mouse Faecal Metaproteome
Nalpas, N.; Hoyles, L.; Anselm, V.; Ganief, T.; Martinez-Gili, L.; Grau, C.; Droste-Borel, I.; Davidovic, L.; Altafaj, X.; Dumas, M.-E.; Macek, B.
10.1101/2020.11.17.386938 — microbiology — Posted on 2020-11-17
1803 Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex
Beckham, K. S. H.; Ritter, C.; Chojnowski, G.; Mullapudi, E.; Rettel, M.; Savitski, M. M.; Mortensen, S. A.; Kosinski, J.; Wilmanns, M.
10.1101/2020.11.17.387225 — microbiology — Posted on 2020-11-17
1804 Single-colony sequencing reveals phylosymbiosis, co-phylogeny, and horizontal gene transfer between the cyanobacterium Microcystis and its microbiome
Perez-Carrascal, O. M.; Tromas, N.; Terrat, Y.; Moreno, E.; Giani, A.; Braga Marques, L. C.; Fortin, N.; Shapiro, B. J.
10.1101/2020.11.17.386995 — microbiology — Posted on 2020-11-17
1805 A continuously self-sterilizing form of copper capable of 99% SARS-CoV-2 deactivation in 30 seconds.
Zinn, A. A.; Izadjoo, M.; Kim, H.; Kehn-Hall, K.; Lehman, C.; Brody, R. L.; Roth, R. R.; Vega, A.; Nguyen, K. K.; Ngo, N. T.; Zinn, H. T.; Panny, L.; Flor, R.; Antonopoulos, N.; Stoltenberg, R. M.
10.1101/2020.11.16.384040 — immunology — Posted on 2020-11-17
1806 An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19
Rappazzo, C. G.; Tse, L. V.; Kaku, C. I.; Wrapp, D.; Sakharkar, M.; Huang, D.; Deveau, L. M.; Yockachonis, T. J.; Herbert, A. S.; Battles, M. B.; O'Brien, C. M.; Brown, M. E.; Geoghegan, J. C.; Belk, J.; Peng, L.; Yang, L.; Scobey, T. D.; Burton, D. R.; Nemazee, D.; Dye, J. M.; Voss, J. E.; Gunn, B. M.; McLellan, J. S.; Baric, R. S.; Gralinski, L. E.; Walker, L. M.
10.1101/2020.11.17.385500 — immunology — Posted on 2020-11-17
1807 The proteomic landscape of resting and activated CD4+ T cells reveal insights into cell differentiation and function
Subbannayya, Y.; Haug, M.; Pinto, S.; Mohanty, V.; Meas, H. Z.; Prasad, T. S. K.; Flo, T. H.; Kandasamy, R. K.
10.1101/2020.11.17.385096 — immunology — Posted on 2020-11-17
1808 Maturation and persistence of the anti-SARS-CoV-2 memory B cell response.
Sokal, A.; Chappert, P.; Roeser, A.; Barba-Spaeth, G.; Fourati, S.; Azzaoui, I.; Vandenberghe, A.; Fernandez, I.; Bouvier-Alias, M.; Crickx, E.; Beldi Ferchiou, A.; Hue, S.; Languille, L.; Baloul, S.; Noizat-Pirenne, F.; Luka, M.; Megret, J.; Menager, M.; Pawlotsky, J.-M.; Fillatreau, S.; Rey, F. A.; Weill, J.-C.; Reynaud, C.-A.; Mahevas, M.
10.1101/2020.11.17.385252 — immunology — Posted on 2020-11-17
1812 An expanding manifold characterizes adolescent reconfigurations of structural connectome organization
Park, B.-y.; Bethlehem, R. A. I.; Paquola, C.; Lariviere, S.; Cruces, R. R.; Vos de Wael, R.; Neuroscience in Psychiatry Network (NSPN) Consortium, ; Bullmore, E. T.; Bernhardt, B.
10.1101/2020.06.22.165621 — neuroscience — Posted on 2020-11-17
1815 Optimal Adaptive Electrode Selection to Maximize Simultaneously Recorded Neuron Yield
Choi, J.; Kumar, K.; Khazali, M.; Wingel, K.; Choudhury, M.; Charles, A.; Pesaran, B.
10.1101/2020.10.06.328526 — neuroscience — Posted on 2020-11-17
1817 Immunoproteasome impairment via β5i/LMP7-deletion leads to sustained pancreatic injury and delayed recovery from experimental pancreatitis.
de Freitas Chama, L. L.; Ebstein, F.; Wiesrecker, B.; Wagh, P. R.; Weiss, F. U.; Lerch, M. M.; Krueger, E.; Sendler, M.
10.1101/2020.11.17.386482 — physiology — Posted on 2020-11-17
1820 Genome Diversity in Ukraine
Oleksyk, T. K.; Wolfsberger, W. W.; Weber, A.; Shchubelka, K.; Oleksyk, O. T.; Levchuk, O.; Patrus, A.; Lazar, N.; Castro-Marquez, S. O.; Boldyzhar, P.; Urbanovych, A.; Stakhovska, V.; Malyar, K.; Chervyakova, S.; Podoroha, O.; Kovalchuk, N.; Neymet, M.; Hasynets, Y.; Rodriguez-Flores, J. L.; Medley, S.; Battistuzzi, F. U.; Liu, R.; Hou, Y.; Chen, S.; Yang, H.; Yeager, M.; Dean, M.; Mills, R. E.; Smolanka, V.
10.1101/2020.08.07.238329 — genomics — Posted on 2020-11-17
1824 Evidence for natural hybridisation and novel Wolbachia strain superinfections in the Anopheles gambiae complex from Guinea
Jeffries, C. L.; Cansado Utrilla, C.; Beavogui, A. H.; Stica, C.; Lama, E. K.; Kristan, M.; Irish, S. R.; Walker, T.
10.1101/772855 — ecology — Posted on 2020-11-17
1827 Preclinical evaluation of Imatinib does not support its use as an antiviral drug against SARS-CoV-2
Touret, F.; Driouich, J.-S.; Cochin, M.; Petit, P. R.; Gilles, M.; Barthelemy, K.; Moureau, G.; Malvy, D.; Solas, C.; de Lamballerie, X.; Nougairede, A.
10.1101/2020.11.17.386904 — microbiology — Posted on 2020-11-17
1828 Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck
Braun, K. M.; Moreno, G. K.; Halfmann, P. J.; Baker, D. A.; Boehm, E. C.; Weiler, A. M.; Haj, A. K.; Hatta, M.; Chiba, S.; Maemura, T.; Kawaoka, Y.; Koelle, K.; O'Connor, D.; Friedrich, T.
10.1101/2020.11.16.384917 — microbiology — Posted on 2020-11-17
1829 Mosaic RBD nanoparticles elicit neutralizing antibodies against SARS-CoV-2 and zoonotic coronaviruses
Bjorkman, P. J.; Cohen, A. A.; Gnanapragasam, P. N. P.; Lee, Y. E.; Ou, S.; Kakutani, L. M.; Keeffe, J. R.; Barnes, C. O.; Nussenzweig, M. C.
10.1101/2020.11.17.387092 — immunology — Posted on 2020-11-17
1830 Reinforcing neuron extraction and spike inference in calcium imaging using deep self-supervised learning
Li, X.; Zhang, G.; Wu, J.; Zhang, Y.; Zhao, Z.; Lin, X.; Qiao, H.; Xie, H.; Wang, H.; Fang, L.; Dai, Q.
10.1101/2020.11.16.383984 — neuroscience — Posted on 2020-11-17
1832 Photostimulation of lymphatic clearance of red blood cells from the mouse brain after intraventricular hemorrhage
Li, D.; Liu, S.; Yu, T.; Liu, Z.; Sun, S.; Bragin, D.; Navolokin, N.; Kurths, J.; Semyachkina-Glushkovskaya, O. V.; Zhu, D.
10.1101/2020.11.16.384149 — neuroscience — Posted on 2020-11-17
1836 Perphenazine-macrocycle conjugates divert Aβ42 towards non-toxic aggregates by monomer sequestration.
Ball, S. R.; Adamson, J. S.; Sullivan, M. A.; Zimmermann, M. R.; Lo, V.; Sanz-Hernandez, M.; Jiang, F.; Kwan, A. H.; Werry, E. L.; Knowles, T. P.; Kassiou, M.; Meisl, G.; Todd, M. H.; Rutledge, P. R.; Sunde, M.
10.1101/2020.11.16.384248 — biophysics — Posted on 2020-11-17
1837 Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer's disease
Meisl, G.; Zuo, Y.; Allinson, K.; Rittman, T.; DeVos, S.; Sanchez, J. S.; Xu, C. K.; Duff, K. E.; Johnson, K. A.; Rowe, J.; Hyman, B.; Knowles, T. P.; Klenerman, D.
10.1101/2020.11.16.384727 — biophysics — Posted on 2020-11-17
1839 Comprehensive generation, visualization, and reporting of quality control metrics for single-cell RNA sequencing data
Hong, R.; Koga, Y.; Bandyadka, S.; Leshchyk, A.; Wang, Z.; Alabdullatif, S.; Wang, Y.; Akavoor, V.; Cao, X.; Sarfraz, I.; Jansen, F.; Johnson, W. E.; Yajima, M.; Campbell, J. D.
10.1101/2020.11.16.385328 — bioinformatics — Posted on 2020-11-17
1841 Low Repeatability of Aversive Learning in Zebrafish (Danio rerio)
Mason, D.; Zajitschek, S.; Anwer, H.; O'Dea, R.; Hesselson, D.; Nakagawa, S.
10.1101/2020.11.16.385930 — animal behavior and cognition — Posted on 2020-11-17
1842 Methylation Quantitative Trait Loci are Largely Consistent across Disease States in Crohns disease
Venkateswaran, S.; Somineni, H. K.; Kilaru, V.; Kartrinli, S.; Prince, J.; Okou, D.; Hyams, J. S.; Lee, D. A.; Kellermayer, R.; Gibson, G.; Cutler, D.; Smith, A. K.; Kugathasan, S.; Conneely, K.
10.1101/2020.11.16.385534 — genomics — Posted on 2020-11-17
1847 Microbial function is related to behavior of an invasive anuran
Zhou, J.; Nelson, T. M.; Rodriguez Lopez, C.; Zhou, S. J.; Ward-Fear, G.; Stuart, K. C.; Rollins, L. A.
10.1101/2020.11.16.385690 — microbiology — Posted on 2020-11-17
1848 Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers predicting HBsAg loss
Xiong, S.; Zhu, D.; Liang, B.; Li, M.; Pan, W.; He, J.; Wang, H.; Kathrin, S.; Ulf, D.; Lu, M.; Liu, D.; Yang, D.; Liu, J.; Zheng, X.
10.1101/2020.11.16.382838 — microbiology — Posted on 2020-11-17
1850 Remote Digital Psychiatry: MindLogger for Mobile Mental Health Assessment and Therapy
Klein, A.; Clucas, J.; Krishnakumar, A.; Ghosh, S. S.; Van Auken, W.; Thonet, B.; Sabram, I.; Acuna, N.; Keshavan, A.; Rossiter, H.; Xiao, Y.; Semenuta, S.; Badioli, A.; Konishcheva, K.; Abraham, S. A.; Alexander, L. M.; Merikangas, K. R.; Swendsen, J.; Lindner, A. B.; Milham, M. P.
10.1101/2020.11.16.385880 — neuroscience — Posted on 2020-11-17
1853 Simplified and unified access to cancer proteogenomic data
Lindgren, C. M.; Adams, D. W.; Kimball, B.; Boekweg, H.; Tayler, S.; Pugh, S. L.; Payne, S. H.
10.1101/2020.11.16.385427 — bioinformatics — Posted on 2020-11-17
1856 Engineering self-organized criticality in living cells
Vidiella Rocamora, B.; Guillamon, A.; Sardanyes, J.; Maull, V.; Pueyo, N. C.; Sole, R.
10.1101/2020.11.16.385385 — bioengineering — Posted on 2020-11-17
1859 Draft Genome Assemblies and Annotations of Agrypnia vestita Walker, and Hesperophylaxmagnus Banks Reveal Substantial Repetitive Element Expansion in Tube Case-making Caddisflies (Insecta: Trichoptera)
Olsen, L. K.; Heckenhauer, J.; Sproul, J. S.; Dikow, R. B.; Gonzalez, V. L.; Kweskin, M. P.; Taylor, A. M.; Wilson, S. B.; Stewart, R. J.; Zhou, X.; Holzenthal, R.; Pauls, S. U.; Frandsen, P. B.
10.1101/2020.11.16.381806 — genomics — Posted on 2020-11-17
1861 Castration delays epigenetic aging and feminises DNA methylation at androgen-regulated loci
Sugrue, V. J.; Zoller, J. A.; Narayan, P.; Lu, A. T.; Ortega-Recalde, O. J.; Grant, M. J.; Bawden, C. S.; Rudiger, S. R.; Haghani, A.; Bond, D. M.; Garratt, M.; Sears, K. E.; Wang, N.; Yang, X.; Snell, R. G.; Hore, T. A.; Horvath, S.
10.1101/2020.11.16.385369 — developmental biology — Posted on 2020-11-17
1870 Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutations
Ursu, O.; Neal, J. T.; Shea, E.; Thakore, P. I.; Jerby-Arnon, L.; Nguyen, L.; Dionne, D.; Diaz, C.; Bauman, J.; Mosaad, M.; Fagre, C.; Giacomelli, A.; Ly, S. H.; Rozenblatt-Rosen, O.; Hahn, W.; Aguirre, A.; Berger, A.; Regev, A.; Boehm, J. S.
10.1101/2020.11.16.383307 — genomics — Posted on 2020-11-17
1871 K-seq, an affordable, reliable, and open Klenow NGS-based genotyping technology
Ziarsolo, P.; Hasing, T.; Hilario, R.; Garcia-Carpintero, V.; Blanca, J. M.; Bombarely, A.; Canizares, J.
10.1101/2020.11.16.360446 — genetics — Posted on 2020-11-17
1872 Temperature heterogeneity correlates with intraspecific variation in physiological flexibility in a small endotherm
Stager, M.; Senner, N. R.; Swanson, D. L.; Carling, M. D.; Eddy, D. K.; Grieves, T. J.; Cheviron, Z. A.
10.1101/2020.11.16.383877 — evolutionary biology — Posted on 2020-11-17
1875 Bacteria in biogas digestates for reduced climate forcing
Jonassen, K. R.; Hagen, L. H.; Vick, S.; Arntzen, M.; Eijsink, V. G. H.; Frostegard, A.; Lycus, P.; Molstad, L.; Bakken, L. R.
10.1101/2020.11.16.384990 — microbiology — Posted on 2020-11-17
1876 Identification of Covalent Modifications Regulating Immune Signaling Complex Composition and Phenotype
Frauenstein, A.; Ebner, S.; Sinha, A.; Kshiti, P.; Swatek, K.; Hornburg, D.; Mann, M.; Meissner, F.
10.1101/2020.11.16.384750 — systems biology — Posted on 2020-11-17
1877 Plant PhysioSpace: a robust tool to compare stress response across plant species
Hadizadeh Esfahani, A.; Mass, J.; Hallab, A.; Schuldt, B. M.; Usadel, B.; Ott, M.-C.; Buer, B.; Schuppert, A.
10.1101/2020.11.16.384305 — plant biology — Posted on 2020-11-17
1879 Inhibition of Fis1 by Novel Peptide Pep213 or Molecular Suppression Reverses Diabetic- and High Glucose-Induced Endothelial Dysfunction in Human Resistance Arteries
Karkala, M.; Egner, J.; Wang, J.; Harwig, M. C.; Meacham, K.; Puppala, V. K.; Hofeld, B. C.; Arnold, L. A.; Hill, R. B.; Widlansky, M. E.
10.1101/2020.11.16.385054 — physiology — Posted on 2020-11-17
1882 MegaGO: a fast yet powerful approach to assess functional similarity across meta-omics data sets
Verschaffelt, P.; Van Den Bossche, T.; Gabriel, W.; Burdukiewicz, M.; Soggiu, A.; Martens, L.; Renard, B. Y.; Schiebenhoefer, H.; Mesuere, B.
10.1101/2020.11.16.384834 — bioinformatics — Posted on 2020-11-17
1885 Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq
Mylka, V.; Aerts, J.; Matetovici, I.; Poovathingal, S.; Vandamme, N.; Seurinck, R.; Hulselmans, G.; Van den Hoecke, S.; Wils, H.; Reumers, J.; Van Houdt, J.; Aerts, S.; Saeys, Y.
10.1101/2020.11.16.384222 — genomics — Posted on 2020-11-17
1886 Holocene plant diversity revealed by ancient DNA from 10 lakes in northern Fennoscandia
Rijal, D. P.; Heintzman, P. D.; Lammers, Y.; Yoccoz, N. G.; Lorberau, K. E.; Pitelkova, I.; Goslar, T.; Murguzur, F. J. A.; Salonen, J. S.; Helmens, K. F.; Bakke, J.; Edwards, M. E.; Alm, T.; Brathen, K. A.; Brown, A. G.; Alsos, I. G.
10.1101/2020.11.16.384065 — ecology — Posted on 2020-11-17
1893 Bifocal tACS Enhances Visual Motion Discrimination by Modulating Phase Amplitude Coupling Between V1 and V5 Regions
Salamanca, R.; Raffin, E.; Zandvliet, S.; Seeber, M.; Michel, C.; Sauseng, P.; Huxlin, K. R.; Hummel, F.
10.1101/2020.11.16.382267 — neuroscience — Posted on 2020-11-17
1895 Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients
Wong, S.; Ehrhart, E.; Stewart, S.; Zismann, V.; Cawley, J.; Halperin, R.; Briones, N.; Richter, K.; Sivaprakasam, K.; Perdigones, N.; Contente-Cuomo, T.; Facista, S.; Trent, J. M.; Murtaza, M.; Khanna, C.; Hendricks, W. P. D.
10.1101/2020.11.15.380048 — cancer biology — Posted on 2020-11-17
1897 Multiscale PHATE Exploration of SARS-CoV-2 Data Reveals Multimodal Signatures of Disease
Kuchroo, M.; Huang, J.; Wong, P.; Grenier, J.-C.; Shung, D.; Tong, A.; Lucas, C.; Klein, J.; Burkhardt, D.; Gigante, S.; Godavarthi, A.; Israelow, B.; Mao, T.; Oh, J. E.; Silva, J.; Takahashi, T.; Odio, C. D.; Casanovas-Massana, A.; Fournier, J.; IMPACT Team, Y.; Farhadian, S.; Dela Cruz, C. S.; Ko, A. I.; Wilson, F. P.; Hussin, J.; Wolf, G.; Iwasaki, A.; Krishnaswamy, S.
10.1101/2020.11.15.383661 — bioinformatics — Posted on 2020-11-17
1901 Hydrogel-coating improves the in-vivo stability of electrochemical aptamer-based biosensors
Li, S.; Dai, J.; Zhu, M.; Arroyo-Curras, N.; Li, H.; Wang, Y.; Wang, Q.; Lou, X.; Kippin, T. E.; Wang, S.; Plaxco, K. W.; Li, H.; Xia, F.
10.1101/2020.11.15.383992 — bioengineering — Posted on 2020-11-17
1902 Novel quaternary structures of the human prion protein globular domain
Oliveira Bortot, L.; Lopes Rangel, V.; A. Pavlovici, F.; El Omari, K.; Wagner, A.; Brandao-Neto, J.; Talon, R.; von Delft, F.; G Reidenbach, A.; M Vallabh, S.; Vallabh Minikel, E.; Schreiber, S.; Cristina Nonato, M.
10.1101/2020.11.16.385856 — biochemistry — Posted on 2020-11-17
1905 Comprehensive mapping of tissue cell architecture via integrated single cell and spatial transcriptomics
Kleshchevnikov, V.; Shmatko, A.; Dann, E.; Aivazidis, A.; King, H. W.; Li, T.; Lomakin, A.; Kedlian, V.; Jain, M. S.; Park, J. S.; Ramona, L.; Tuck, E.; Arutyunyan, A.; Vento-Tormo, R.; Gerstung, M.; James, L.; Stegle, O.; Bayraktar, O. A.
10.1101/2020.11.15.378125 — genomics — Posted on 2020-11-17
1906 The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects
Fridman, H.; Yntema, H. G.; Magi, R.; Andreson, R.; Metspalu, A.; Mezzavila, M.; Tyler-Smith, C.; Xue, Y.; Carmi, S.; Levy-Lahad, E.; Gilissen, C.; Brunner, H.
10.1101/2020.11.16.384206 — genetics — Posted on 2020-11-17
1907 Genomic and anatomical comparisons of skin support independent adaptation to life in water by cetaceans and hippos
Springer, M. S.; Guerrero-Juarez, C.; Huelsmann, M.; Collin, M. A.; Danil, K.; McGowen, M. R.; Oh, J. W.; Ramos, R.; Hiller, M.; Plikus, M. V.; Gatesy, J.
10.1101/2020.11.15.383638 — evolutionary biology — Posted on 2020-11-17
1908 A single origin of animal excretory organs
Gasiorowski, L.; Andrikou, C.; Bump, P.; Janssen, R.; Budd, G. E.; Lowe, C. J.; Hejnol, A.
10.1101/2020.11.15.378034 — evolutionary biology — Posted on 2020-11-17
1909 Multidimensionality in the thermal niches of dung beetles could limit species' responses to temperature changes
Calatayud, J.; Hortal, J.; Noriega, J. A.; Arcones, A.; Espinoza, V.; Guil, N.; Lobo, J. M.
10.1101/2020.11.15.383612 — ecology — Posted on 2020-11-17
1910 Predicting potential impacts of ocean acidification on marine calcifiersfrom the Southern Ocean
Figuerola, B.; Hancock, A. M.; Bax, N.; Cummings, V.; Downey, R.; Griffiths, H. J.; Smith, J.; Stark, J. S.
10.1101/2020.11.15.384131 — ecology — Posted on 2020-11-17
1911 Modelling species presence-only data with random forests
Valavi, R.; Elith, J.; Lahoz-Monfort, J. J.; Guillera-Arroita, G.
10.1101/2020.11.16.384164 — ecology — Posted on 2020-11-17
1912 Chondrocytes in the resting zone of the growth plate are maintained in a Wnt-inhibitory environment
Hallett, S. A.; Ono, W.; Matsushita, Y.; Sakagami, N.; Mizuhashi, K.; Tokavanich, N.; Nagata, M.; Zhou, A.; Hirai, T.; Kronenberg, H. M.; Ono, N.
10.1101/2020.11.15.383331 — developmental biology — Posted on 2020-11-17
1913 The nature of mitotic forces in epithelial monolayers
Gupta, V. K.; Nam, S.; Camuglia, J.; Martin, J. L.; Sanders, E. N.; O'Brien, L. E.; Martin, A. C.; Kim, T.; Chaudhuri, O.
10.1101/2020.11.16.378927 — cell biology — Posted on 2020-11-17
1914 Computer Designed PRC2 Inhibitor, EBdCas9, Reveals Functional TATA boxes in Distal Promoter Regions
Levy, S.; Somasundaram, L.; Xavier Raj, I.; Ic-Mex, D.; Schmidt, S.; Alghadeer, A.; Honkanen, H.; Hawkins, D. D.; Mathieu, J.; Wang, Y.; Baker, D.; Bomsztyk, K.; Ruohola-Baker, H.
10.1101/2020.11.16.385922 — molecular biology — Posted on 2020-11-17
1916 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-17
1917 Proteomic analysis reveals Utf1 as a neurogenesis-associated new Sumo target
Correa-Vazquez, J. F.; Juarez-Vicente, F.; Garcia-Gutierrez, P.; Barysch, S. V.; Melchior, F.; Garcia-Dominguez, M.
10.1101/2020.11.17.386557 — cell biology — Posted on 2020-11-17
1918 HIV-1 provirus excised by single CRISPR/Cas9 RNA guide persists in host cell and may be reactivated
Lai, M.; Maori, E.; Quaranta, P.; Matteoli, G.; Maggi, F.; Sgarbanti, M.; Crucitta, S.; Paci, S.; Turriziani, O.; Freer, G.; Heeney, J. L.; Antonelli, G.; Pistello, M.
10.1101/2020.11.16.384180 — microbiology — Posted on 2020-11-17
1923 Quaternary climate change explains global patterns of tree beta-diversity
Xu, W.-B.; Guo, W.-Y.; Serra-Diaz, J. M.; Schrodt, F.; Eiserhardt, W. L.; Enquist, B. J.; Maitner, B. S.; Merow, C.; Violle, C.; Anand, M.; Belluau, M.; Bruun, H. H.; Byun, C.; Catford, J. A.; Cerabolini, B. E. L.; Chacon-Madrigal, E.; Ciccarelli, D.; Cornelissen, J. H. C.; Dang-Le, A. T.; de Frutos, A.; Dias, A. S.; Giroldo, A. B.; Gutierrez, A. G.; Hattingh, W.; He, T.; Hietz, P.; Hough-Snee, N.; Jansen, S.; Kattge, J.; Komac, B.; Kraft, N.; Kramer, K.; Lavorel, S.; Lusk, C. H.; Martin, A. R.; Ma, K.-P.; Mencuccini, M.; Michaletz, S. T.; Minden, V.; Mori, A. S.; Niinemets, U.; Onoda, Y.; Ons
10.1101/2020.11.14.382846 — ecology — Posted on 2020-11-17
1924 Lysyl oxidase-like 2 (LOXL2) is Increased in Asthma and Contributes to Asthmatic Airway Remodelling
Ramis, J.; Middlewick, R.; Pappalardo, F.; Cairns, J. T.; Stewart, I. D.; John, A. E.; Naveed, S.-u.; Krishnan, R.; Miller, S.; Shaw, D. E.; Brightling, C. E.; Buttery, L.; Rose, F. R.; Jenkins, G.; Johnson, S. R.; Tatler, A. L.
10.1101/2020.11.16.384792 — cell biology — Posted on 2020-11-17
1927 A Streptomyces venezuelae Cell-Free Toolkit for Synthetic Biology
Moore, S.; Lai, H.-E.; Chee, S.-M.; Toh, M.; Coode, S.; Capel, P.; Corre, C.; de los Santos, E.; Freemont, P.
10.1101/2020.11.16.384693 — synthetic biology — Posted on 2020-11-17
1930 Methyltransferase SMYD5 Exaggerates IBD by Downregulating Mitochondrial Functions via Post-translational Control of PGC-1α Stability
Hou, Y.; Sun, X.; Gheinani, P. T.; Guan, X.; Sharma, S.; Zhou, Y.; Jin, C.; Yang, Z.; Naren, A. P.; Yin, J.; Denning, T. L.; Gewirtz, A. T.; Xie, Z.; Li, C.
10.1101/2020.11.16.385765 — cell biology — Posted on 2020-11-17
1934 A novel human fetal liver-derived model reveals that MLL-AF4 drives a distinct fetal gene expression program in infant ALL
Rice, S.; Jackson, T.; Crump, N. T.; Fordham, N.; Elliott, N.; O Byrne, S.; Inglott, S.; Ladon, D.; Wright, G.; Bartram, J.; Ancliff, P.; Mead, A. J.; Halsey, C.; Roberts, I.; Milne, T. A.; Roy, A.
10.1101/2020.11.15.379990 — cancer biology — Posted on 2020-11-17
1936 Revisiting the notion of deleterious sweeps
Johri, P.; Charlesworth, B.; Howell, E. K.; Lynch, M.; Jensen, J. D.
10.1101/2020.11.16.385666 — evolutionary biology — Posted on 2020-11-17
1937 Threat-induced hippocampal connectivity fingerprints do not generalize to psychosocial stress
Kuehnel, A.; Czisch, M.; Saemann, P. G.; BeCome working group, ; Binder, E. B.; Kroemer, N. B.
10.1101/2020.11.16.380220 — neuroscience — Posted on 2020-11-17
1939 Distinct and Common Neural Coding of Semantic and Non-semantic Control Demands
Gao, Z.; Zheng, L.; Chiou, R.; Gouws, A.; Krieger-Redwood, K.; Wang, X.; Varga, D.; Lambon Ralph, M.; Smallwood, J.; Jefferies, E.
10.1101/2020.11.16.384883 — neuroscience — Posted on 2020-11-17
1941 HOX13-MEDIATED DBX2 REGULATION IN LIMBS SUGGESTS INTER-TAD SHARING OF ENHANCERS
Beccari, L.; Jaquier, G.; Lopez-Delisle, L.; Rodriguez-Carballo, E.; Mascrez, B.; Gitto, S.; Woltering, J.; Duboule, D.
10.1101/2020.11.16.379412 — developmental biology — Posted on 2020-11-17
1945 Metabolic potential, ecology and presence of endohyphal bacteria is reflected in genomic diversity of Mucoromycotina
Muszewska, A.; Okrasinska, A.; Steczkiewicz, K.; Drgas, O.; Orłowska, M.; Perlinska-Lenart, U.; Aleksandrzak-Piekarczyk, T.; Szatraj, K.; Zielenkiewicz, U.; Piłsyk, S.; Malc, E.; Mieczkowski, P.; Kruszewska, J. S.; Bernat, P.; Pawłowska, J.
10.1101/2020.11.16.384453 — genomics — Posted on 2020-11-16
1947 Evaluation of saliva as a source of accurate whole-genome and microbiome sequencing data
Herzig, A.; Velo-Suarez, L.; Le Folgoc, G.; Boland, A.; Blanche, H.; Olaso, R.; Le Roux, L.; Delmas, C.; Goldberg, M.; Zins, M.; Lethimonnier, F.; Deleuze, J.-F.; Genin, E.
10.1101/2020.11.16.384438 — genetics — Posted on 2020-11-16
1949 Phylodynamic analysis of an emergent Mycobacterium bovis outbreak in an area with no previously known wildlife infections
Rossi, G.; Crispell, J.; Brough, T.; Lycett, S. J.; White, P. C. L.; Allen, A.; Ellis, R. J.; Gordon, S. V.; Harwood, R.; Palkopoulou, E.; Presho, E.; Skuce, R.; Smith, G. C.; Kao, R. R.
10.1101/2020.11.12.379297 — ecology — Posted on 2020-11-16
1950 Seizing diminishing habitat conservation and restoration opportunities in the Tampa Bay, FL watershed: An urban estuary in recovery
Raulerson, G. E.; Robison, D. E.; Beck, M. W.; Burke, M. C.; Ries, T. F.; Saarinen, J. A.; Sciarrino, C. M.; Sherwood, E. T.; Tomasko, D. A.
10.1101/2020.11.16.384404 — ecology — Posted on 2020-11-16
1957 Color compensation in anomalous trichromats assessed with fMRI
Tregillus, K. E. M.; Isherwood, Z. J.; Vanston, J. E.; Engel, S. A.; MacLeod, D. I. A.; Kuriki, I.; Webster, M. A.
10.1101/2020.08.18.256701 — neuroscience — Posted on 2020-11-16
1958 Multiomics data collection, visualization, and utilization for guiding metabolic engineering
Roy, S.; Radivojevic, T.; Forrer, M.; Marti, J. M.; Jonnalagadda, V.; Backman, T.; Morrell, W.; Plahar, H.; Kim, J.; Hillson, N.; Martin, H. G.
10.1101/2020.10.15.341909 — synthetic biology — Posted on 2020-11-16
1959 Comprehensive studies of Head Maralla, Punjab, Pakistan vegetation for ethnopharmacological and ethnobotanical uses and their elaboration through quantitative indices
Iqbal, M. S.; Ali, M. A.; Akbar, M.; Hussain, S. A.; Arshad, N.; Masood, H.; Munir, S.; Zafar, S.; Ahmad, T.; Shaheen, N.; Mashooq, R.; Sajjad, H.; Zahoor, M.; Bashir, F.; Shahbaz, K.; Arshad, H.; Fatima, N.; Nasir, F.; Hashmi, A. J.; Chaudhary, S.; Waqas, A.; Islam, M.
10.1101/2020.11.16.384420 — plant biology — Posted on 2020-11-16
1961 An Arf/Rab cascade controls the growth and invasiveness of glioblastoma
Kulasekaran, G.; Chaineau, M.; Piscapo, V. E.; Verginelli, F.; Fotouhi, M.; Girard, M.; Tang, Y.; Dali, R.; Lo, R.; Stifani, S.; McPherson, P. S.
10.1101/2020.04.30.070334 — cancer biology — Posted on 2020-11-16
1962 Streamlining Data-Intensive Biology With Workflow Systems
Reiter, T.; Brooks, P. T.; Irber, L.; Joslin, S. E. K.; Reid, C. M.; Scott, C.; Brown, C. T.; Pierce, N. T.
10.1101/2020.06.30.178673 — bioinformatics — Posted on 2020-11-16
1964 Predicting clinical drug response from model systems by non-linear subspace-based transfer learning
Mourragui, S.; Loog, M.; Vis, D. J.; Moore, K.; Manjon, A. G.; van de Wiel, M. A.; Reinders, M. J. T.; Wessels, L. F. A.
10.1101/2020.06.29.177139 — bioinformatics — Posted on 2020-11-16
1965 HGNChelper: Identification and correction of invalid gene symbols for human and mouse
Oh, S.; Abdelnabi, J.; Al-Dulaimi, R.; Aggarwal, A.; Ramos, M.; Davis, S. R.; Riester, M.; Waldron, L. D.
10.1101/2020.09.16.300632 — bioinformatics — Posted on 2020-11-16
1968 DNA Replication Stress Generates Distinctive Landscapes of DNA Copy Number Alterations and Chromosome Scale Losses
Shaikh, N.; Mazzagatti, A.; Bakker, B.; Spierings, D. C. J. E.; Wardenaar, R.; Maniati, E.; Larsson, P.; Wang, J.; Boemo, M. A.; Foijer, F.; McClelland, S. E.
10.1101/743658 — genomics — Posted on 2020-11-16
1969 Trees and their seed networks: the social dynamics of urban fruit trees and implications for genetic diversity
Rimlinger, A.; Avana, M.-L.; Awono, A.; Chakocha, A.; Gakwavu, A.; Lemoine, T.; Marie, L.; Mboujda, F.; Vigouroux, Y.; Johnson, V.; Vinceti, B.; Carriere, S. M.; Duminil, J.
10.1101/2020.11.16.384388 — ecology — Posted on 2020-11-16
1972 ARID1A regulates R-loop associated DNA replication stress
Stirling, P.; Tsai, S.; Chang, E. Y.-C.; Fournier, L.-A.; Wells, J. P.; Minaker, S. W.; Zhu, Y. D.; Wang, A. Y.-H.; Wang, Y.; Huntsman, D. G.
10.1101/2020.11.16.384446 — cell biology — Posted on 2020-11-16
1974 Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis
Das, B.; Pathak, L.; Gayan, S.; Pal, B.; Saikia, P. j.; Baishya, T.; Das, N. R.; Das, R.; Maral, M.; Mahanta, R.; Bhuyan, S.; Gautam, P.; Talukdar, J.; Sandhya, S.; Kalita, D.; Swami, V.; Das, K. R.; Bora, D. K.; Ghora, J.; Pulu, I.
10.1101/2020.11.14.382572 — immunology — Posted on 2020-11-16
1975 TEA-seq: a trimodal assay for integrated single cell measurement of transcription, epitopes, and chromatin accessibility
Swanson, E.; Lord, C.; Reading, J.; Heubeck, A. T.; Savage, A. K.; Green, R.; Li, X.-j.; Torgerson, T. R.; Bumol, T. F.; Graybuck, L. T.; Skene, P. J.
10.1101/2020.09.04.283887 — immunology — Posted on 2020-11-16
1976 Machine learning analysis of the bleomycin-mouse model reveals the compartmental and temporal inflammatory pulmonary fingerprint
Bordag, N.; Biasin, V.; Schnoegl, D.; Valzano, F.; Jandl, K.; Nagy, B. M.; Sharma, N.; Wygrecka, M.; Kwapiszewska, G.; Marsh, L. M.
10.1101/2020.05.22.106690 — immunology — Posted on 2020-11-16
1978 Conscious processing of narrative stimuli synchronizes heart rate between individuals
Perez, P.; Madsen, J.; Banellis, L.; Turker, B.; Raimondo, F.; Perlbarg, V.; Valente, M.; Nierat, M.-C.; Puybasset, L.; Naccache, L.; Similowski, T.; Cruse, D.; Parra, L. C.; SITT, J.
10.1101/2020.05.26.116079 — neuroscience — Posted on 2020-11-16
1979 Empirical field mapping for gradient nonlinearity correction of multi-site diffusion weighted MRI
Hansen, C. B.; Rogers, B. P.; Schilling, K. G.; Nath, V.; Blaber, J. A.; Irfanoglu, O.; Barnett, A.; Pierpaoli, C.; Anderson, A. W.; Landman, B. A.
10.1101/2020.05.18.102558 — neuroscience — Posted on 2020-11-16
1982 Uncovering hidden members and functions of the soil microbiome using de novo metaproteomics
Lee, J.-Y.; Mitchell, H. D.; Burnet, M. C.; Wu, R.; Jenson, S. C.; Merkley, E. D.; Nakayasu, E. S.; Nicora, C.; Jansson, J. K.; Burnum-Johnson, K. E.; Payne, S.
10.1101/428334 — bioinformatics — Posted on 2020-11-16
1987 Towards understanding predictability in ecology: A forest gap model case study
Raiho, A. M.; Dietze, M.; Dawson, A.; Rollinson, C.; Tipton, J.; McLachlan, J.
10.1101/2020.05.05.079871 — ecology — Posted on 2020-11-16
1989 The CRISPR-Cas9 crGART HeLa transcriptome: A novel cell model of de novo purine synthesis deficiency
Mazzarino, R. C.; Baresova, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.06.23.167924 — cell biology — Posted on 2020-11-16
1990 Recurrent mutations in SARS-CoV-2 genomes isolated from mink point to rapid host-adaptation
van Dorp, L.; Tan, C. C.; Lam, S. D.; Richard, D.; Owen, C.; Berchtold, D.; Orengo, C.; Balloux, F.
10.1101/2020.11.16.384743 — genomics — Posted on 2020-11-16
1991 A core of functionally complementary bacteria colonizes oysters in Pacific Oyster Mortality Syndrome.
Lucasson, A.; Luo, X.; Mortaza, S.; de Lorgeril, J.; Toulza, E.; Petton, B.; Escoubas, J.-M.; Clerissi, C.; Degremont, L.; Gueguen, Y.; Destoumieux Garzon, D.; Jacq, A.; Mitta, G.
10.1101/2020.11.16.384644 — microbiology — Posted on 2020-11-16
1992 Iron can be microbially extracted from Lunar and Martian regolith simulants and 3D printed into tough structural materials
Castelein, S. M.; Aarts, T. F.; Schleppi, J.; Hendrikx, R.; Böttger, A.; Benz, D.; Marechal, M.; Makaya, A.; Brouns, S. J.; Schwentenwein, M.; Meyer, A. S.; Lehner, B. A. E.
10.1101/2020.11.15.382614 — microbiology — Posted on 2020-11-16
1993 The discriminatory power of the T cell receptor
Huhn, A.; Wilson, D. B.; van der Merwe, P. A.; Dushek, O.
10.1101/2020.11.16.384495 — immunology — Posted on 2020-11-16
1997 Analysis of SARS-CoV-2 spike glycosylation reveals shedding of a vaccine candidate
Brun, J.; Vasiljevic, S.; Gangadharan, B.; Hensen, M.; Chandran, A. V.; Hill, M. L.; Kiappes, J. L.; Dwek, R. A.; Alonzi, D. S.; Struwe, W. B.; Zitzmann, N.
10.1101/2020.11.16.384594 — biochemistry — Posted on 2020-11-16
1998 Desert Dingo (Canis lupus dingo) genome provides insights into their role in the Australian ecosystem.
Yadav, S.; Dudchenko, O.; Esvaran, M.; Rosen, B. D.; Field, M. D.; Skvortsova, K.; Edwards, R. J.; Gopalakrishnan, S.; Keilwagen, J.; Cochran, B. J.; Manandhar, B.; Bucknall, M.; Bustamante, S.; Rasmussen, J. A.; Melvin, R. G.; Omer, A.; Colaric, Z.; Chan, E. K. F.; Minoche, A. E.; Smith, T. P.; Gilbert, M. T. P.; Bogdanovic, O.; Zammit, R. A.; Thomas, T.; Aiden, E. L.; Ballard, J. W. O.
10.1101/2020.11.15.384057 — genomics — Posted on 2020-11-16
1999 DeepMosaic: Control-independent mosaic single nucleotide variant detection using deep convolutional neural networks
Yang, X.; Xu, X.; Breuss, M. W.; Antaki, D.; Ball, L. L.; Chung, C.; Li, C.; George, R. D.; Wang, Y.; Bae, T.; Abyzov, A.; Sebat, J.; Gleeson, J. G.
10.1101/2020.11.14.382473 — genomics — Posted on 2020-11-16
2001 C. elegans hermaphrodites undergo semelparous reproductive death
Kern, C. C.; Srivastava, S.; Ezcurra, M.; Hui, N.; Townsend, S.; Maczik, D.; Tse, V.; Bähler, J.; Gems, D.
10.1101/2020.11.16.384255 — genetics — Posted on 2020-11-16
2007 Trimeric SARS-CoV-2 Spike proteins produced from CHO-cells in bioreactors are high-quality antigens
Pino, P.; Kint, J.; Kiseljak, D.; Agnolon, V.; Corradin, G.; KAJAVA, A. V.; Rovero, P.; Dijkman, R.; Hartog, G. d.; McLellan, J. S.; Byrne, P.; Wurm, M. J.; Wurm, F. M.
10.1101/2020.11.15.382044 — cell biology — Posted on 2020-11-16
2008 Establishment and characterisation of primary skeletal muscle cell cultures from patients with advanced Chronic Kidney Disease
Baker, L. A.; O'Sullivan, T. F.; Robinson, K. A.; Redshaw, Z.; Graham-Brown, M.; Ashford, R. U.; Smith, A. C.; Philp, A.; Watson, E. L.
10.1101/2020.11.16.384263 — cell biology — Posted on 2020-11-16
2010 Immune Checkpoint Blockade induces peripheral cytotoxicity and persistence of large effector CD8+ T cell clones
Watson, R. A.; Tong, O.; Cooper, R. A.; Taylor, C. A.; Verge de los Aires, A.; Mahe, E.; Nassiri, I.; Middleton, M. R.; Fairfax, B. P.
10.1101/2020.11.15.383786 — immunology — Posted on 2020-11-16
2011 Divergent profiles of fentanyl withdrawal and associated pain in mice and rats
Uddin, O.; Jenne, C.; Fox, M. E.; Arakawa, K.; Keller, A.; Cramer, N. P.
10.1101/2020.11.16.384818 — neuroscience — Posted on 2020-11-16
2014 A Streptomyces venezuelae Cell-Free Toolkit for Synthetic Biology
Moore, S.; Lai, H.-E.; Chee, S.-M.; Toh, M.; Coode, S.; Capel, P.; Corre, C.; de los Santos, E.; Freemont, P.
10.1101/2020.11.16.384693 — synthetic biology — Posted on 2020-11-16
2016 Biomolecular Condensation Drives Leukemia Caused by NUP98-Fusion Proteins
Terlecki-Zaniewicz, S.; Eder, T.; Schmoellerl, J.; Humer, T.; Kuchynka, N.; Parapatics, K.; Heyes, E.; Liberante, F. G.; Müller, A. C.; Grebien, F.
10.1101/2020.11.16.384271 — cancer biology — Posted on 2020-11-16
2017 The bone microenvironment invigorates metastatic seeds for further dissemination
Zhang, W.; Bado, I. L.; Hu, J.; Wan, Y.-W.; Wu, L.; Wang, H.; Gao, Y.; Jeong, H.-H.; Xu, Z.; Hao, X.; Lege, B. M.; Al-Ouran, R.; Li, L.; Li, J.; Yu, L.; Singh, S.; Lo, H.-C.; Niu, M.; Liu, J.; Jiang, W.; Li, Y.; Wong, S. T. C.; Cheng, C.; Liu, Z.; Zhang, X. H. - F.
10.1101/2020.11.16.383828 — cancer biology — Posted on 2020-11-16
2018 A novel human fetal liver-derived model reveals that MLL-AF4 drives a distinct fetal gene expression program in infant ALL
Rice, S.; Jackson, T.; Crump, N. T.; Fordham, N.; Elliott, N.; O Byrne, S.; Inglott, S.; Ladon, D.; Wright, G.; Bartram, J.; Ancliff, P.; Mead, A. J.; Halsey, C.; Roberts, I.; Milne, T. A.; Roy, A.
10.1101/2020.11.15.379990 — cancer biology — Posted on 2020-11-16
2019 Machine learning aided top-down protein identification on a microfluidic platform
Zhang, Y.; Wright, M.; Saar, K. L.; Challa, P.; Morgunov, A. S.; Peter, Q. A. E.; Devenish, S.; Dobson, C. M.; Knowles, T. P. J.
10.1101/2020.11.14.381376 — biophysics — Posted on 2020-11-16
2020 Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules
Mitteaux, J.; Lejault, P.; Pirrotta, M.; Wojciechowski, F.; Joubert, A.; Desbois, N.; Gros, C. P.; Hudson, R. H. E.; Boule, J.-B.; Granzhan, A.; Monchaud, D.
10.1101/2020.11.16.382176 — biophysics — Posted on 2020-11-16
2021 α-Synuclein emerges as a potent regulator of VDAC-facilitated calcium transport
Rosencrans, W. M.; Aguilella, V. M.; Rostovtseva, T. K.; Bezrukov, S. M.
10.1101/2020.11.15.383729 — biophysics — Posted on 2020-11-16
2025 Distinct hydrogenotrophic bacteria are stimulated by elevated H2 levels in upland and wetland soils
Xu, Y.; Teng, Y.; Dong, X.; Wang, X.; Zhang, C.; Ren, W.; Zhao, L.; Luo, Y.; Greening, C.
10.1101/2020.11.15.383943 — bioinformatics — Posted on 2020-11-16
2026 Mimicking the Human Tympanic Membrane: the Significance of Geometry
Anand, S.; Stoppe, T.; Lucena, M.; Rademakers, T.; Neudert, M.; Danti, S.; Moroni, L.; Mota, C.
10.1101/2020.11.14.383299 — bioengineering — Posted on 2020-11-16
2027 A Universal Allosteric Mechanism for G Protein Activation
Knight, K. M.; Ghosh, S.; Campbell, S. L.; Lefevre, T. J.; Olsen, R. H. J.; Smrcka, A. V.; Valentin, N. H.; Yin, G.; Vaidehi, N.; Dohlman, H. G.
10.1101/2020.11.15.383679 — biochemistry — Posted on 2020-11-16
2028 Selection for Decreased BRCA2 Functional Activity in Homo sapiens After Divergence from the Chimpanzee-Human Last Common Ancestor
Iacobuzio-Donahue, C. A.; Huang, J.; Zhong, Y.; Makohon-Moore, A. P.; White, T.; Jasin, M.; Norell, M. A.; Wheeler, W. C.
10.1101/2020.11.16.384677 — evolutionary biology — Posted on 2020-11-16
2031 Automatic whole cell organelle segmentation in volumetric electron microscopy
Heinrich, L.; Bennett, D.; Ackerman, D.; Park, W.; Bogovic, J.; Eckstein, N.; Petruncio, A.; Clements, J.; Xu, C. S.; Funke, J.; Korff, W.; Hess, H.; Lippincott-Schwartz, J.; Saalfeld, S.; Weigel, A.; Project Team, C.
10.1101/2020.11.14.382143 — cell biology — Posted on 2020-11-16
2035 SARS-CoV-2-specific T cell memory is long-lasting in the majority of convalsecent COVID-19 individuals
Li, Z.; Liu, J.; Deng, H.; Yang, X.; Wang, H.; Feng, X.; Zelinskyy, G.; Trilling, M.; Sutter, K.; Lu, M.; Wang, B.; Yang, D.; Zheng, X.; Liu, J.
10.1101/2020.11.15.383463 — microbiology — Posted on 2020-11-16
2036 Effects of inactivation method on SARS-CoV-2 virion proteins and structure
Loveday, E. K.; Hain, K. S.; Kochetkova, I.; Hedges, J. F.; Robison, A.; Snyder, D. T.; Brumfield, S. K.; Young, M. J.; Jutila, M. A.; Chang, C. B.; Taylor, M. P.
10.1101/2020.11.14.383026 — microbiology — Posted on 2020-11-16
2037 High resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies
Garrett, M. E.; Galloway, J.; Chu, H. Y.; Itell, H. L.; Stoddard, C. I.; Wolf, C. R.; Logue, J. K.; McDonald, D.; Matsen, F. A.; Overbaugh, J.
10.1101/2020.11.16.385278 — immunology — Posted on 2020-11-16
2038 Immunological memory to SARS-CoV-2 assessed for greater than six months after infection
Dan, J. M.; Mateus, J.; Kato, Y.; Hastie, K. M.; Faliti, C.; Ramirez, S. I.; Frazier, A.; Yu, E. D.; Grifoni, A.; Rawlings, S. A.; Peters, B.; Krammer, F.; Simon, V.; Saphire, E. O.; Smith, D.; Weiskopf, D.; Sette, A.; Crotty, S.
10.1101/2020.11.15.383323 — immunology — Posted on 2020-11-16
2039 DISSOCIATION BETWEEN INDIVIDUAL DIFFERENCES IN SELF-REPORTED PAIN INTENSITY AND UNDERLYING BRAIN ACTIVATION
Hoeppli, M.-E.; Nahman-Averbuch, H.; Hinkle, W. A.; Leon, E.; Peugh, J.; Lopez-Sola, M.; King, C. D.; Goldschneider, K. R.; Coghill, R. C.
10.1101/2020.11.13.381970 — neuroscience — Posted on 2020-11-16
2042 Hydrophilic Shell Matrix Proteins of Nautilus pompilius and The Identification of a Core Set of Conchiferan Domains
Setiamarga, D. H. E.; Hirota, K.; Yoshida, M.-a.; Takeda, Y.; Kito, K.; Shimizu, K.; Isowa, Y.; Ikeo, K.; Sasaki, T.; Endo, K.
10.1101/2020.11.14.382804 — zoology — Posted on 2020-11-16
2043 Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics
Wang, L.; Muneer, A.; Xie, L.; Zhang, F.; Wu, B.; Mei, L.; Lenarcic, E. M.; Feng, E. H.; Song, J.; Xiong, Y.; Yu, X.; Wang, C.; Gheorghe, C.; Torralba, K.; Cook, J. G.; Wan, Y. Y.; Moorman, N. J.; Song, H.; Jin, J.; Chen, X.
10.1101/2020.11.14.382416 — systems biology — Posted on 2020-11-16
2044 Capturing in-field root system dynamics with the RootTracker
Aguilar, J. J.; Moore, M.; Johnson, L.; Greenhut, R. F.; Rogers, E.; Walker, D.; O'Neil, F.; Edwards, J. L.; Thystrup, J.; Farrow, S.; Windle, J. B.; Benfey, P. N.
10.1101/2020.11.14.382002 — plant biology — Posted on 2020-11-16
2045 Discovery of rhodomyrtone as a broad-spectrum antiviral inhibitor with anti-SARS-CoV-2 activity
Tang, W.; Lu, J.; Song, Q.-Y.; Li, M.-M.; Chen, L.-F.; Hu, L.-J.; Yang, S.-M.; Zhang, D.-M.; Wang, Y.; Li, Y.-L.; Ye, W.-C.
10.1101/2020.11.14.382770 — pharmacology and toxicology — Posted on 2020-11-16
2046 Active elimination of intestinal cells drives oncogenic growth in organoids
Krotenberg Garcia, A.; Fumagalli, A.; Quang Le, H.; Sansom, O. J.; van Rheenen, J.; Suijkerbuijk, S. J.
10.1101/2020.11.14.378588 — cancer biology — Posted on 2020-11-16
2047 The white matter is a pro-differentiative microenvironment for glioblastoma
Brooks, L. J.; Clements, M. P.; Burden, J. J.; Kocher, D.; Richards, L.; Castro Devesa, S.; Woodberry, M.; Ellis, M.; Zakka, L.; Jaunmuktane, Z.; Brandner, S.; Morrison, G.; Pollard, S. M.; Dirks, P. B.; Marguerat, S.; Parrinello, S.
10.1101/2020.11.14.379594 — cancer biology — Posted on 2020-11-16
2050 ISA API: An open platform for interoperable life science experimental metadata
Johnson, D.; Cochrane, K.; Davey, R. P.; Etuk, A.; Gonzalez-Beltran, A.; Haug, K.; Izzo, M.; Larralde, M.; Lawson, T. N.; Minotto, A.; Moreno, P.; Nainala, V. C.; O'Donovan, C.; Pireddu, L.; Roger, P.; Shaw, F.; Steinbeck, C.; Weber, R. J.; Sansone, S.-A.; Rocca-Serra, P.
10.1101/2020.11.13.382119 — bioinformatics — Posted on 2020-11-16
2051 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-16
2053 Trecode: a FAIR eco-system for the analysis and archiving of omics data in a combined diagnostic and research setting
Kerstens, H.; Hehir-Kwa, J.; van de Geer-de Jong, E.; van Run, C.; Verwiel, E.; van der Leest, D.; Tops, B.; Kemmeren, P.
10.1101/2020.11.13.363689 — bioinformatics — Posted on 2020-11-16
2057 Self-organization and culture of Mesenchymal Stromal Cell spheroids in acoustic levitation
Jeger-Madiot, N.; Arakelian, L.; Setterblad, N.; Bruneval, P.; Hoyos, M.; Larghero, J.; Aider, J.-L.
10.1101/2020.11.16.385047 — bioengineering — Posted on 2020-11-16
2058 Single-nuclei RNA-sequencing of plants
Sunaga-Franze, D. Y.; Muino, J.; Braeuning, C.; Xu, X.; Zong, M.; Smaczniak, C.; Yan, W.; Fischer, C.; Vidal, R.; Kliem, M.; Kaufmann, K.; Sauer, S.
10.1101/2020.11.14.382812 — genomics — Posted on 2020-11-16
2059 Combining climatic and genomic data improves range-wide tree height growth prediction in a forest tree
Archambeau, J.; Benito Garzon, M.; Barraquand, F.; de Miguel Vega, M.; Plomion, C.; C. Gonzalez-Martinez, S.
10.1101/2020.11.13.382515 — genetics — Posted on 2020-11-16
2060 Solving the sex ratio scandal in Melittobia wasps
Abe, J.; Iritani, R.; Tsuchida, K.; Kamimura, Y.; West, S. A.
10.1101/2020.11.16.384768 — evolutionary biology — Posted on 2020-11-16
2061 Measuring diversity from space: a global view of the free and open source rasterdiv R package under a coding perspective
Thouverai, E.; Marcantonio, M.; Bacaro, G.; Da Re, D.; Iannacito, M.; Ricotta, C.; Tattoni, C.; Vicario, S.; Rocchini, D.
10.1101/2020.11.14.369371 — ecology — Posted on 2020-11-16
2063 Bacterial density as an unexpected factor regulating decomposition by soil oligotrophs
Coche, A. W.; Babey, T.; Rapaport, A.; Vieuble Gonod, L.; Garnier, P.; Nunan, N.; de Dreuzy, J. R.
10.1101/2020.11.16.384735 — ecology — Posted on 2020-11-16
2073 Interpretable Segmentation of Amyloid-βStained Whole Slide Images of Brain Tissue
Lai, Z.; Guo, R.; Xu, W.; Hu, Z.; Mifflin, K.; Dugger, B. N.; Cheung, S.-c.; Chuah, C.-N.
10.1101/2020.11.13.381871 — neuroscience — Posted on 2020-11-16
2074 Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis
Berland, C.; Castel, J.; Montalban, E.; Foppen, E.; Martin, C.; Muccioli, G. G.; Luquet, S.; Gangarossa, G.
10.1101/2020.11.14.382291 — neuroscience — Posted on 2020-11-16
2076 A computational neural model for mapping degenerate neural architectures
Khan, Z.; Wang, Y.; Sennesh, E. Z.; Dy, J.; Ostadabbas, S.; van de Meent, J.-W.; Hutchinson, J. B.; Satpute, A. B.
10.1101/2020.11.13.382192 — neuroscience — Posted on 2020-11-16
2077 The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle
Diaz-Garcia, C. M.; Meyer, D. J.; Nathwani, N.; Rahman, M.; Martinez-Francois, J. R.; Yellen, G.
10.1101/2020.11.16.385526 — neuroscience — Posted on 2020-11-16
2078 Mutations in the juxtamembrane segment of the cholesterol-binding site of APP alter its processing and promotes production of shorter, less toxic Aβ peptides.
Hanbouch, L.; Schaack, B.; Kasri, A.; Fontaine, G.; Gkanatsiou, E.; Brinkmalm, G.; Portelius, E.; Blennow, K.; Mourier, G.; Gilles, N.; Millan, M. J.; Marquer, C.; Zetterberg, H.; Boussicault, L.; Potier, M.-C.
10.1101/2020.11.16.384891 — neuroscience — Posted on 2020-11-16
2082 Inherent population structure determines the importance of filtering parameters for reduced representation sequencing analyses
Selechnik, D.; Richardson, M. F.; Hess, M.; Hess, A. S.; Dodds, K. G.; Martin, M.; Chan, T. C.; Cardilini, A. P. A.; Sherman, C.; Shine, R.; Rollins, L. A.
10.1101/2020.11.14.383240 — bioinformatics — Posted on 2020-11-16
2091 A freeze-and-thaw induced-fragment of the microtubule-associated protein Tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity
Vasconcelos, I. C.; Campos, R. M. d.; Schwaemmle, H. M. K.; Masson, A. P.; Ferrari, G. D.; Alberici, L. C.; Faca, V. M.; Garcia-Cairasco, N.; Sebollela, A. S.
10.1101/404129 — biochemistry — Posted on 2020-11-16
2092 The translational landscape of SARS-CoV-2 and infected cells
Puray-Chavez, M.; Tenneti, K.; Vuong, H. R.; Lee, N.; Liu, Y.; Horani, A.; Huang, T.; Gunsten, S. P.; Case, J. B.; Yang, W.; Diamond, M. S.; Brody, S. L.; Dougherty, J.; Kutluay, S. B.
10.1101/2020.11.03.367516 — microbiology — Posted on 2020-11-16
2093 Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerase (PARP), blocks replication of the SARS-CoV-2 human coronavirus in vitro.
Stone, N. E.; Jaramillo, S. A.; Jones, A. N.; Vazquez, A. J.; Martz, M.; Versluis, L. M.; Raniere, M. O.; Nunnally, H. E.; Zarn, K. E.; Nottingham, R.; Sahl, J. W.; Wagner, D. M.; Knudsen, S.; Settles, E. W.; Keim, P. S.; French, C. T.
10.1101/2020.11.12.380394 — microbiology — Posted on 2020-11-16
2094 Large-scale monitoring of resistance to coumaphos, amitraz and pyrethroids in Varroa destructor
Hernandez-Rodriguez, C. S.; Marin, O.; Calatayud, F.; Mahiques, M. J.; Mompo, A.; Segura, I.; Simo, E.; Gonzalez-Cabrera, J.
10.1101/2020.11.12.378190 — pharmacology and toxicology — Posted on 2020-11-16
2096 European Primary Forest Database (EPFD) v2.0
Sabatini, F. M.; Bluhm, H.; Kun, Z.; Aksenov, D.; Atauri, J. A.; Buchwald, E.; Burrascano, S.; Cateau, E.; Diku, A.; Marques Duarte, I.; Fernandez Lopez, A. B.; Garbarino, M.; Grigoriadis, N.; Horvath, F.; Keren, S.; Kitenberga, M.; Kis, A.; Kraut, A.; Ibisch, P. L.; Larrieu, L.; Lombardi, F.; Matovic, B.; Melu, R. N.; Meyer, P.; Midteng, R.; Mikac, S.; Mikolas, M.; Mozgeris, G.; Panayotov, M.; Pisek, R.; Nunes, L.; Ruete, A.; Schickhofer, M.; Simovski, B.; Stillhard, J.; Stojanovic, D.; Szwagrzyk, J.; Tikkanen, O.-P.; Toromani, E.; Volosyanchuk, R.; Vrska, T.; Waldherr, M.; Yermokhin, M.; Zla
10.1101/2020.10.30.362434 — ecology — Posted on 2020-11-16
2099 Loss of ASH1L in developing brains causes autistic-like behaviors in a mouse model
Gao, Y.; Duque-Wilckens, N.; Aljazi, M. B.; Wu, Y.; Moeser, A. J.; Mias, G. I.; Robison, A. J.; He, J.
10.1101/2020.11.16.377259 — neuroscience — Posted on 2020-11-16
2101 Measuring protected-area outcomes with leech iDNA: large-scale quantification of vertebrate biodiversity in Ailaoshan reserve
Ji, Y.; Baker, C. C.; Li, Y.; Popescu, V. D.; Wang, Z.; Wang, J.; Wang, L.; Wu, C.; Hua, C.; Yang, Z.; Yang, C.; Xu, C. C.; Wen, Q.; Pierce, N. E.; Yu, D. W.
10.1101/2020.02.10.941336 — ecology — Posted on 2020-11-16
2102 Thalamic spontaneous activity coordinates the timing of corticothalamic innervation in the visual system
Lopez-Bendito, G.; Moreno-Juan, V.; Martini, F.; Perez-Saiz, L.; Vadeolmillos, M.; Herrero-Navarro, A.
10.1101/2020.11.13.382366 — neuroscience — Posted on 2020-11-16
2104 Rapid HIV-1 capsid interaction screening using fluorescence fluctuationspectroscopy
Lau, D.; Walsh, J. C.; Dickson, C. F.; Tuckwell, A.; Stear, J. H.; Hunter, D. J. B.; Bhumkar, A.; Shah, V.; Turville, S. G.; Sierecki, E.; Gambin, Y.; Jacques, D. A.; Böcking, T.
10.1101/2020.11.13.382242 — biophysics — Posted on 2020-11-16
2106 Transmission and antibiotic resistance of Achromobacter in cystic fibrosis
Gabrielaite, M.; Bartell, J. A.; Norskov-Lauritsen, N.; Pressler, T.; Nielsen, F. C.; Johansen, H. K.; Marvig, R. L.
10.1101/2020.08.04.235952 — genomics — Posted on 2020-11-16
2107 Deep learning and automated Cell Painting reveal Parkinson's disease-specific signatures in primary patient fibroblasts
Schiff, L.; Migliori, B.; Chen, Y.; Carter, D.; Bonilla, C.; Hall, J.; Fan, M.; Tam, E.; Ahadi, S.; Fischbacher, B.; Geraschenko, A.; Hunter, C. J.; Venugopalan, S.; DesMarteau, S.; Narayanaswamy, A.; Jacob, S.; Armstrong, Z.; Ferrarotto, P.; Williams, B.; Buckley-Herd, G.; Hazard, J.; Goldberg, J.; Coram, M.; Otto, R.; Baltz, E. A.; Andres-Martin, L.; Pritchard, O.; Duren-Lubanski, A.; Reggio, K.; Global Stem Cell Array Team, N.; Bauer, L.; Aiyar, R. S.; Schwarzbach, E.; Paull, D.; Noggle, S. A.; Monsma, F. J.; Berndl, M.; Yang, S. J.; Johannesson, B.
10.1101/2020.11.13.380576 — cell biology — Posted on 2020-11-16
2108 GJA1 Depletion Causes Ciliary Defects by Affecting Rab11 Trafficking to the Ciliary Base
Jang, D. G.; Kwon, K. Y.; Kweon, Y. C.; Kim, B.-g.; Myung, K.; Lee, H.-S.; Young Park, C.; Kwon, T.; Park, T. J.
10.1101/2020.11.13.381764 — cell biology — Posted on 2020-11-16
2109 An Entropic Safety Catch Controls Hepatitis C Virus Entry and Antibody Resistance.
Stejskal, L.; Kalemera, M. D.; Palor, M.; Walker, L.; Daviter, T.; Lees, W. D.; Moss, D. S.; Kremyda-Vlachou, M.; Kozlakidis, Z.; Rosenberg, W.; Illingworth, C. J. R.; Shepherd, A. J.; Grove, J.
10.1101/2020.11.11.377218 — molecular biology — Posted on 2020-11-16
2110 The cell fate controlling CLE40 peptide requires CNGC9 to trigger highly localized Ca2+ transients in Arabidopsis thaliana root meristems
Breiden, M.; Olsson, V.; Gustavo Pinto, K.; Bluemke, P.; Denay, G.; Schlegel, J.; Dietrich, P.; Butenko, M. A.; Simon, R.
10.1101/2020.11.13.381111 — plant biology — Posted on 2020-11-16
2113 The role of microglia membrane potential in chemotaxis
Laprell, L.; Schulze, C.; Brehme, M.-L.; Oertner, T. G.
10.1101/2020.05.19.104109 — neuroscience — Posted on 2020-11-16
2114 A Bayesian semi-parametric model for thermal proteome profiling
Fang, S.; Kirk, P. D.; Bantscheff, M.; Lilley, K. S.; Crook, O.
10.1101/2020.11.14.382747 — systems biology — Posted on 2020-11-16
2115 Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
Zhang, S.; Cooper-Knock, J.; Weimer, A. K.; Shi, M.; Moll, T.; Harvey, C.; Nezhad, H. G.; Franklin, J.; Souza, C. d. S.; Wang, C.; Li, J.; Eitan, C.; Hornstein, E.; Kenna, K. P.; Project MinE Sequencing Consortium, ; Veldink, J.; Ferraiuolo, L.; Shaw, P. J.; Snyder, M. P.
10.1101/2020.11.14.382606 — genomics — Posted on 2020-11-16
2117 Gene-environment interactions in Multiple Sclerosis: a UK Biobank study
Jacobs, B. M.; Noyce, A.; Bestwick, J. P.; Belete, D.; Giovannoni, G.; Dobson, R.
10.1101/2020.03.01.971739 — genetics — Posted on 2020-11-16
2119 Characterizing the Emergence of Liver and Gallbladder from the Embryonic Endoderm through Single-Cell RNA-Seq
Mu, T.; Xu, L.; Zhong, Y.; Liu, X.; Zhao, Z.; Huang, C.; Lan, X.; Lufei, C.; Zhou, Y.; Su, Y.; Xu, L.; Jiang, M.; Zhou, H.; Lin, X.; Wu, L.; Peng, S.; Liu, S.; Pedersen, S. B.; Dean, M.; Dunn, N. R.; Zaret, K. S.; Fu, X.-Y.; Hou, Y.
10.1101/718775 — developmental biology — Posted on 2020-11-16
2120 FcγR responses to soluble immune complexes of varying size: A scalable cell-based reporter system
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2020-11-16
2123 DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring dynamic changes in health, ageing and degeneration
Tam, V.; Chen, P.; Yee, A.; Solis, N.; Klein, T.; Kudelko, M.; Sharma, R.; Chan, W. C.; Overall, C. M.; Haglund, L.; Sham, P. C.; Cheah, K. S.; Chan, D.
10.1101/2020.07.11.192948 — systems biology — Posted on 2020-11-16
2125 C. elegans provide milk for their young
Kern, C. C.; Townsend, S.; Salzmann, A.; Rendell, N. B.; Taylor, G. W.; Comisel, R. M.; Foukas, L. C.; Bähler, J.; Gems, D.
10.1101/2020.11.15.380253 — genetics — Posted on 2020-11-15
2126 A Bayesian semi-parametric model for thermal proteome profiling
Fang, S.; Kirk, P. D.; Bantscheff, M.; Lilley, K. S.; Crook, O.
10.1101/2020.11.14.382747 — systems biology — Posted on 2020-11-15
2129 CRISPAltRations: a validated cloud-based approach for interrogation of double-strand break repair mediated by CRISPR genome editing
Kurgan, G.; Turk, R.; Li, H.; Rettig, G. R.; Jacobi, A. M.; Tso, L.; Mertens, M.; Noten, R.; Florus, K.; Behlke, M. A.; Wang, Y.; McNeill, M. S.
10.1101/2020.11.13.382283 — bioinformatics — Posted on 2020-11-15
2134 Phenotypic and Genetic Markers of Psychopathology in a Population-Based Sample of Older Adults
Gard, A. M. S.; Ware, E. B.; Hyde, L. W.; Schmitz, L.; Faul, J.; Mitchell, C.
10.1101/601609 — genomics — Posted on 2020-11-15
2136 Multiple types of navigational information are independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-11-15
2140 Phenotypic plasticity of ER+ breast cancer in the bone microenvironment
Bado, I. L.; Wang, H.; Hu, J.; Sarkar, P.; Liu, J.; Gugala, Z.; Xu, Z.; Zhang, W.; Wu, W.; Lo, H.-C.; Li, L.; Kim, I.-S.; Singh, S.; Janghorban, M.; Muscallera, A.; Goldstein, A.; Singh, P.; Jeong, H. H.; Wan, Y.-W.; Shixia, H.; Schiff, R.; Waleed, G. M.; Liu, Z.; Ellis, M. J.; Zhang, X. H. F.
10.1101/2020.11.14.383000 — cancer biology — Posted on 2020-11-15
2145 Identification of novel Alzheimer's disease genes co-expressed with TREM2
Reddy, J. S.; Allen, M.; Wang, X.; Biernacka, J. M.; Coombes, B. J.; Jenkins, G. D.; Sinnwell, J. P.; Carrasquillo, M. M.; Pottier, C. P.; Ren, Y.; Sarangi, V.; Younkin, C. S.; Asmann, Y. W.; Ross, O. A.; Rademakers, R.; Golde, T. E.; Ertekin-Taner, N.; Steven, Y. G.
10.1101/2020.11.13.381640 — genetics — Posted on 2020-11-15
2146 Linking biotic homogenisation with large-scale changes of species associations
Rigal, S.; Devictor, V.; Gaüzere, P.; Kefi, S.; Forsman, J. T.; Kajanus, M. H.; Mönkkönen, M.; Dakos, V.
10.1101/2020.11.13.380956 — ecology — Posted on 2020-11-15
2147 Uncoordinated long-patch base excision repair at juxtaposed DNA lesions generates a lethal accumulation of double-strand breaks
Shimada, K.; Van Loon, B.; Gerhold, C. B.; Bregenhorn, S.; Hurst, V.; Tarashev, C.; Roth, G.; Heinis, C.; Jiricny, J.; Gasser, S. M.
10.1101/2020.11.15.383513 — molecular biology — Posted on 2020-11-15
2152 Computational characteristics of interictal EEG as objective markers of epileptic spasms
Smith, R. J.; Hu, D. K.; Shrey, D. W.; Rajaraman, R.; Hussain, S. A.; Lopour, B. A.
10.1101/2020.11.13.380691 — neuroscience — Posted on 2020-11-15
2154 Multiple types of navigational information are independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-11-15
2158 Brain disconnectivity mapping of post-stroke fatigue
Ulrichsen, K. M.; Kolskaar, K. K.; Richard, G.; Alnaes, D.; Dorum, E. S.; Sanders, A.-M.; Tornaas, S.; Sanchez, J. M.; Engvig, A.; Ihle-Hansen, H.; Thiebaut de Schotten, M.; Nordvik, J. E.; Westlye, L. T.
10.1101/2020.11.13.380972 — neuroscience — Posted on 2020-11-15
2160 Stimulus-specific plasticity of macaque V1 spike rates and gamma
Peter, A. S.; Stauch, B. J.; Shapcott, K.; Kouroupaki, K.; Schmiedt, J. T.; Klein, L.; Klon-Lipok, J.; Dowdall, J. R.; Schoelvinck, M. L.; Vinck, M.; Singer, W.; Schmid, M. C.; Fries, P.
10.1101/2020.11.13.381418 — neuroscience — Posted on 2020-11-15
2161 Nutrient signaling pathways regulate amyloid clearance and synaptic loss in Alzheimer's disease
Mondal, M.; Bali, J.; Tzioras, M.; Paolicelli, R. C.; Malnar, M.; Dominko, K.; Jawaid, A.; Udayar, V.; Ben Halima, S.; Vadodaria, K. C.; Manesso, E.; Thakur, G.; Decressac, M.; Petit, C.; Sudharshan, R.; Hecimovic, S.; Simons, M.; Klumperman, J.; Bruestle, O.; Ferguson, S.; Nitsch, R.; Schulz, P. E.; Spires-Jones, T. L.; Koch, P.; Gunawan, R.; Rajendran, L.
10.1101/2020.11.13.381186 — neuroscience — Posted on 2020-11-15
2162 The single pass membrane protein MRAP2 regulates energy homeostasis by promoting primary cilia localization of the G protein-coupled receptor MC4R
Bernard, A. A.; Ojeda Naharros, I.; Bourgain-Guglielmetti, F.; Ciprin, J.; Yue, X.; Zhang, S.; McDaid, E.; Nachury, M. V.; Reiter, J.; Vaisse, C.
10.1101/2020.11.13.382325 — neuroscience — Posted on 2020-11-15
2163 High-resolution transcriptome atlas and improved genome assembly of common buckwheat, Fagopyrum esculentum
Penin, A. A.; Kasianov, A. S.; Klepikova, A. V.; Kirov, I. V.; Gerasimov, E. S.; Fesenko, A. N.; Logacheva, M. D.
10.1101/2020.11.14.382903 — plant biology — Posted on 2020-11-15
2167 The spliceosome inhibitors isoginkgetin and pladienolide B induce ATF3-dependent cell death
Vanzyl, E. J.; Sayed, H.; Blackmore, A. B.; Rick, K. R. C.; Fernando, P.; McKay, B. C.
10.1101/821363 — cell biology — Posted on 2020-11-15
2169 Cold-associated mammokines preserve adipocyte identity
Santos, L. C.; Arneson, D.; Chella Krishnan, K.; Ahn, I. S.; Diamante, G.; Cely, I.; Butte, A. J.; Lusis, A. J.; Yang, X.; Rajbhandari, P.
10.1101/2020.11.14.378687 — cell biology — Posted on 2020-11-15
2171 Tobramycin adaptation enhances policing of social cheaters in Pseudomonas aeruginosa
Abisado, R.; Kimbrough, J. H.; McKee, B. M.; Craddock, V.; Smalley, N.; Dandekar, A. A.; Chandler, J. R.
10.1101/2020.11.15.383836 — microbiology — Posted on 2020-11-15
2175 T cells exhibit unexpectedly low discriminatory power and can respond to ultra-low affinity peptide-MHC ligands
Pettmann, J.; Abu-Shah, E.; Kutuzov, M.; Wilson, D. B.; Dustin, M.; Davis, S.; van der Merwe, P. A.; Dushek, O.
10.1101/2020.11.14.382630 — immunology — Posted on 2020-11-15
2176 Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis
Das, B.; Pathak, L.; Gayan, S.; Pal, B.; Saikia, P. j.; Baishya, T.; Das, N. R.; Das, R.; Maral, M.; Mahanta, R.; Bhuyan, S.; Gautam, P.; Talukdar, J.; Sandhya, S.; Kalita, D.; Swami, V.; Das, K. R.; Bora, D. K.; Ghora, J.; Pulu, I.
10.1101/2020.11.14.382572 — immunology — Posted on 2020-11-15
2177 Endogenous variation in ventromedial prefrontal cortex state dynamics during naturalistic viewing reflects affective experience
Chang, L. J.; Jolly, E.; Cheong, J. H.; Rapuano, K.; Greenstein, N.; Chen, P.-H. A.; Manning, J. R.
10.1101/487892 — neuroscience — Posted on 2020-11-15
2178 Saccadic modulation of neural activity in the human anterior thalamus during visual active sensing
Leszczynski, M.; Staudigl, T.; Chaieb, L.; Enkirch, S. J.; Fell, J.; Schroeder, C. E.
10.1101/2020.03.30.015628 — neuroscience — Posted on 2020-11-15
2183 Anatomic position determines oncogenic specificity in melanoma
Weiss, J. M.; Hunter, M. V.; Tagore, M.; Ma, Y.; Misale, S.; Simon-Vermot, T.; Campbell, N. R.; Newell, F.; Wilmott, J. S.; Johansson, P. A.; Thompson, J. F.; Long, G. V.; Pearson, J. V.; Mann, G. J.; Scolyer, R. A.; Waddell, N.; Montal, E. D.; Huang, T.-H.; Jonsson, P.; Donoghue, M. T. A.; Harris, C. C.; Taylor, B. S.; Ariyan, C. E.; Solit, D. B.; Wolchok, J. D.; Merghoub, T.; Rosen, N.; Hayward, N. K.; White, R. M.
10.1101/2020.11.14.383083 — cancer biology — Posted on 2020-11-15
2186 precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions
Olson, N. D.; Wagner, J.; McDaniel, J.; Stephens, S. H.; Westreich, S. T.; Prasanna, A. G.; Johanson, E.; Boja, E.; Maier, E. J.; Serang, O.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Kyriakidis, K.; Malousi, A.; Shafin, K.; Pesout, T.; Jain, M.; Paten, B.; Chang, P.-C.; Kolesnikov, A.; Nattestad, M.; Baid, G.; Goel, S.; Yang, H.; Carroll, A.; Eveleigh, R.; Bourgey, M.; Bourque, G.; Li, G.; MA, C.; Tang, L.; DU, Y.; Zhang, S.; Morata, J.; Tonda, R.; Parra, G.; Trotta, J.-R.; Brueffer, C.; Demirkaya-Budak, S.; Kabakci-Zorlu, D.; Turgut, D.; Kalay
10.1101/2020.11.13.380741 — bioinformatics — Posted on 2020-11-15
2187 Nuclear lamin A/C promotes cancer cell survival and lung metastasis without restricting transendothelial migration
Roncato, F.; Regev, O.; Feigelson, S. W.; Yadav, S. K.; Kaczmarczyk, L.; Levi, N.; Drago-Garcia, D.; Ovadia, S.; Kizner, M.; Addadi, Y.; Sabino, J. C.; Ovadya, Y.; de Almeida, S. F.; Feldmesser, E.; Gerlitz, G.; Alon, R.
10.1101/2020.06.23.167130 — cancer biology — Posted on 2020-11-15
2189 Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
Zhang, S.; Cooper-Knock, J.; Weimer, A. K.; Shi, M.; Moll, T.; Harvey, C.; Nezhad, H. G.; Franklin, J.; Souza, C. d. S.; Wang, C.; Li, J.; Eitan, C.; Hornstein, E.; Kenna, K. P.; Project MinE Sequencing Consortium, ; Veldink, J.; Ferraiuolo, L.; Shaw, P. J.; Snyder, M. P.
10.1101/2020.11.14.382606 — genomics — Posted on 2020-11-15
2190 Adipose-tissue derived signals control bone remodelling.
Madel, M.-B.; Fu, H.; Pierroz, D.; Schiffrin, M.; Winkler, C.; Wilson, A.; Pochon, C.; Toffoli, B.; Jouzeau, J.-Y.; Gilardi, F.; Ferrari, S.; Bonnet, N.; BLIN-WAKKACH, C.; Desvergne, B.; MOULIN, D.
10.1101/2020.03.02.972711 — cell biology — Posted on 2020-11-15
2192 Fra1 is required for TGFβ1 induced collective invasion
Camacho, S.; Nasir, A.; Rahhal, R.; Dominguez, M.; Pearson, G. W.
10.1101/2020.11.14.383232 — cancer biology — Posted on 2020-11-15
2194 The primary cilium is required for MC4R control of food intake and body weight
Wang, Y.; Bernard, A. A.; Comblain, F.; Yue, X.; Paillart, C.; Zhang, S.; Reiter, J.; Vaisse, C.
10.1101/2020.11.13.382234 — physiology — Posted on 2020-11-15
2195 Single-femtosecond atomic-resolution observation of a protein traversing a conical intersection
Hosseinizadeh, A.; Breckwoldt, N.; Fung, R.; Sepehr, R.; Schmidt, M.; Schwander, P.; Santra, R.; Ourmazd, A.
10.1101/2020.11.13.382218 — biophysics — Posted on 2020-11-15
2203 Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
Hewitt, V. L.; Miller-Fleming, L.; Andreazza, S.; Mattedi, F.; Prudent, J.; Polleux, F.; Vagnoni, A.; Whitworth, A. J.
10.1101/2020.11.14.382861 — cell biology — Posted on 2020-11-15
2204 Cold-associated mammokines preserve adipocyte identity
Santos, L. C.; Arneson, D.; Chella Krishnan, K.; Ahn, I. S.; Diamante, G.; Cely, I.; Butte, A. J.; Yang, X.; Lusis, A. J.; Rajbhandari, P.
10.1101/2020.11.14.378687 — cell biology — Posted on 2020-11-15
2207 Template-independent genome editing and repairing correct frameshift disease in vivo
Liu, L.; Li, K.; Zou, L.; Hou, H.; Hu, Q.; Liu, S.; Wang, S.; Wang, Y.; Li, J.; Song, C.; Chen, J.; Li, C.; Du, H.; Li, J.-L.; Chen, F.; Xu, Z.; Sun, W.; Sun, Q.; Xiong, W.
10.1101/2020.11.13.381160 — neuroscience — Posted on 2020-11-15
2208 Upregulated functionality of mitochondria-associated ER membranes in a mouse model of traumatic brain injury
Agrawal, R. R.; Larrea, D.; Shi, L.; Song, D.; Xu, Y.; Yun, T. D.; Emmanuele, V.; Cummins, L. G.; Macaluso, F. P.; Kernie, S. G.; Min, W.; Deckelbaum, R. J.; Area-Gomez, E.
10.1101/2020.11.13.381756 — neuroscience — Posted on 2020-11-15
2209 PSD-95 in dorsal CA1 contributes to the persistence of fear memory
Ziolkowska, M.; Borczyk, M.; Nowacka, A.; Nalberczak-Skora, M.; Sliwinska, M. A.; Robaca, M.; Lukasiewicz, K.; Caly, A.; Skonieczna, E.; Tomaszewski, K. F.; Wojtowicz, T.; Wlodarczyk, J.; Bernas, T.; Salamian, A.; Radwanska, K.
10.1101/2020.11.13.381368 — neuroscience — Posted on 2020-11-15
2213 A high-quality, chromosome-level genome assembly of the Black Soldier Fly (Hermetia Illucens L.)
Generalovic, T. N.; McCarthy, S. A.; Warren, I. A.; Wood, J. M. D.; Torrance, J.; Sims, Y.; Quail, M.; Howe, K.; Pipan, M.; Durbin, R.; Jiggins, C. D.
10.1101/2020.11.13.381889 — genomics — Posted on 2020-11-15
2214 Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
Zhang, S.; Cooper-Knock, J.; Weimer, A. K.; Shi, M.; Moll, T.; Harvey, C.; Nezhad, H. G.; Franklin, J.; Souza, C. d. S.; Wang, C.; Li, J.; Eitan, C.; Hornstein, E.; Kenna, K. P.; Project MinE Sequencing Consortium, ; Veldink, J.; Ferraiuolo, L.; Shaw, P. J.; Snyder, M. P.
10.1101/2020.11.14.382606 — genomics — Posted on 2020-11-15
2215 Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
Roberts Kingman, G. A.; Vyas, D. N.; Jones, F. C.; Brady, S. D.; Chen, H. I.; Reid, K.; Millhaven, M.; Bertino, T. S.; Aguirre, W. E.; Heins, D. C.; von Hippel, F. A.; Park, P. J.; Kirch, M.; Absher, D.; Myers, R. M.; Di Palma, F.; Bell, M. A.; Kingsley, D. M.; Veeramah, K. R.
10.1101/2020.11.13.382424 — evolutionary biology — Posted on 2020-11-15
2218 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme
Lazaro, M.; Melero, R.; Huet, C.; Lopez-Alonso, J. P.; Delgado, S.; Dodu, A.; Bruch, E. M.; Abriata, L. A.; Alzari, P. M.; Valle, M.; Lisa, M.-N.
10.1101/2020.11.14.381715 — microbiology — Posted on 2020-11-15
2220 Far-red fluorescent genetically encoded calcium ion indicators
Dalangin, R.; Drobizhev, M.; Molina, R. S.; Aggarwal, A.; Patel, R.; Abdelfattah, A. S.; Zhao, Y.; Wu, J.; Podgorski, K.; Schreiter, E. R.; Hughes, T. E.; Campbell, R. E.; Shen, Y.
10.1101/2020.11.12.380089 — neuroscience — Posted on 2020-11-15
2221 Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
Uemura, T.; Suzuki, E.; Kawase, S.; Kurihara, T.; Yasumura, M.; Yoshida, T.; Fukai, S.; Yamazaki, M.; Fei, P.; Abe, M.; Watanabe, M.; Sakimura, K.; Mishina, M.; Tabuchi, K.
10.1101/2020.11.14.383158 — neuroscience — Posted on 2020-11-15
2225 X-ray Irradiation activates immune response in human T-lymphocytes by eliciting a Ca2+ signaling cascade
Thiel, G.; Tandl, D. H.; Sponagel, T.; Fuck, S.; Smit, T.; Hehlgans, S.; Jakob, B.; Fournier, C.; Roedel, F.; Roth, B.; Moroni, A.
10.1101/2020.11.13.379982 — biophysics — Posted on 2020-11-15
2229 Hidden cell diversity in Placozoa: Ultrastructural Insights from Hoilungia hongkongensis
Romanova, D. Y.; Varoqueaux, F.; Daraspe, J.; Nikitin, M. A.; Eitel, M.; Fasshauer, D.; Moroz, L. L.
10.1101/2020.11.13.382382 — evolutionary biology — Posted on 2020-11-14
2231 Exploring correlations in cultural and genetic variation across language families in Northeast Asia
Matsumae, H.; Ranacher, P.; Savage, P. E.; Blasi, D. E.; Currie, T. E.; Koganebuchi, K.; Tanabe, H.; Sato, T.; Nishida, N.; Tajima, A.; Brown, S.; Stoneking, M.; Shimizu, K. K. K.; Oota, H.; Bickel, B.
10.1101/513929 — evolutionary biology — Posted on 2020-11-14
2234 Interdependence of CTL and NK cells cytotoxicity against melanoma cells
Friedmann, K. S.; Knoerck, A.; Cappello, S.; Hoxha, C.; Schwaer, G.; Iden, S.; Bogeski, I.; Kummerow, C.; Schwarz, E. C.; Hoth, M.
10.1101/2020.06.14.150672 — immunology — Posted on 2020-11-14
2235 A Pig White Matter Atlas and Common Connectivity Space Provide a Roadmap for the Introduction of a New Animal Model in Translational Neuroscience
Benn, R. A.; Mars, R. B.; Xu, T.; Rodriguez-Esparragoza, L.; Montesinos, P.; Manzano-Patron, J. P.; Lopez-Martin, G.; Fuster, V.; Sanchez-Gonzalez, J.; Duff, E. P.; Ibanez, B.
10.1101/2020.10.13.337436 — neuroscience — Posted on 2020-11-14
2236 Neural Fragility as an EEG Marker of the Seizure Onset Zone
Li, A.; Huynh, C.; Fitzgerald, Z.; Cajigas, I.; Brusko, D.; Claudio, A.; Jagid, J.; Kanner, A.; Hopp, J.; Chen, S.; Haagensen, J.; Johnson, E.; Crone, N.; Anderson, W.; Inati, S.; Zaghloul, K.; Bulacio, J.; Martinez, J.; Sarma, S.
10.1101/862797 — neuroscience — Posted on 2020-11-14
2245 Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation
Heap, R. E.; Marin Rubio, J. L.; Peltier, J.; Heunis, T.; Dannoura, A.; Moore, A.; Trost, M.
10.1101/2020.08.20.259515 — immunology — Posted on 2020-11-14
2247 Intracranial recordings from human auditory cortex reveal a neural population selective for musical song
Norman-Haignere, S.; Feather, J.; Boebinger, D.; Brunner, P.; Ritaccio, A.; McDermott, J. H.; Schalk, G.; Kanwisher, N.
10.1101/696161 — neuroscience — Posted on 2020-11-14
2249 GeneBreaker: Variant simulation to improve the diagnosis of Mendelian rare genetic diseases
Richmond, P. A.; Av-Shalom, T. V.; Fornes, O.; Modi, B.; Elliott, A. M.; Wasserman, W. W.
10.1101/2020.05.29.124495 — genomics — Posted on 2020-11-14
2251 Endogenous variation in ventromedial prefrontal cortex state dynamics during naturalistic viewing reflects affective experience
Chang, L. J.; Jolly, E.; Cheong, J. H.; Rapuano, K.; Greenstein, N.; Chen, P.-H. A.; Manning, J. R.
10.1101/487892 — neuroscience — Posted on 2020-11-14
2252 Analysis of the Dynamics and Distribution of SARS-CoV-2 Mutations and its Possible Structural and Functional Implications
Justo Arevalo, S.; Zapata Sifuentes, D.; Huallpa Robles, C.; Landa Bianchi, G.; Castillo Chavez, A.; Garavito-Salini Casas, R.; Pineda Chavarria, R.; Uceda-Campos, G.
10.1101/2020.11.13.381228 — genomics — Posted on 2020-11-14
2253 A comparison of DNA/RNA extraction protocols for high-throughput sequencing of microbial communities
Shaffer, J. P.; Marotz, C.; Belda-Ferre, P.; Martino, C.; Wandro, S.; Estaki, M.; Salido, R. A.; Carpenter, C. S.; Zaramela, L. S.; Minich, J. J.; Bryant, M. B.; Sanders, K.; Fraraccio, S.; Ackermann, G.; Humphrey, G.; Swafford, A. D.; Miller-Montgomery, S.; Knight, R.
10.1101/2020.11.13.370387 — ecology — Posted on 2020-11-14
2254 Isotropic 3D electron microscopy reference library of whole cells and tissues
Xu, C. S.; Pang, S.; Shtengel, G.; Müller, A.; Ritter, A. T.; Hoffman, H. K.; Takemura, S.-y.; Lu, Z.; Pasolli, H. A.; Iyer, N.; Chung, J.; Bennett, D.; Weigel, A. V.; Walther, T. C.; Farese, R. V.; van Engelenburg, S. B.; Mellman, I.; Solimena, M.; Hess, H. F.
10.1101/2020.11.13.382457 — cell biology — Posted on 2020-11-14
2256 The Nuclear Pore Complex consists of two independent scaffolds
Regmi, S. G.; Lee, H.; Kaufhold, R.; Fichtman, B.; Chen, S.; Aksenova, V.; Turcotte, E.; Harel, A.; Arnaoutov, A.; Dasso, M.
10.1101/2020.11.13.381947 — cell biology — Posted on 2020-11-14
2257 Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
Alysandratos, K.-D.; Russo, S. J.; Petcherski, A.; Taddeo, E. P.; Acin-Perez, R.; Villacorta-Martin, C.; Jean, J.-C.; Mulugeta, S.; Blum, B. C.; Hekman, R. M.; Vedaie, M.; Kook, S.; Wambach, J. A.; Cole, F. S.; Hamvas, A.; Emili, A.; Guttentag, S. H.; Shirihai, O. S.; Beers, M. F.; Kotton, D. N.
10.1101/2020.11.13.382390 — cell biology — Posted on 2020-11-14
2260 Decoding and blocking the bacterial lipid flippase MprF yields a novel anti-virulence strategy
Slavetinsky, C. J.; Hauser, J. N.; Gekeler, C.; Slavetinsky, J.; Geyer, A.; Kraus, A.; Heilingbrunner, D.; Wagner, S.; Tesar, M.; Weidenmaier, C.; Krismer, B.; Kuhn, S.; Ernst, C. M.; Peschel, A.
10.1101/2020.11.12.379776 — microbiology — Posted on 2020-11-14
2261 Decoding music-evoked emotions in the auditory and motor cortex
Putkinen, V.; Nazari-Farsani, S.; Seppala, K.; Karjalainen, T.; Sun, L.; Karlsson, H. K.; Hudson, M.; Heikkila, T. T.; Hirvonen, J.; Nummenmaa, L.
10.1101/2020.05.24.101667 — neuroscience — Posted on 2020-11-14
2265 Epidermal stem cell compartment remains unaffected through aging in naked mole-rats.
Savina, A.; Jaffredo, T.; Saldmann, F.; Faulkes, C. G.; Moguelet, P.; Leroy, C.; Del Marmol, D.; Codogno, P.; Foucher, L.; Viltard, M.; Friedlander, G.; Aractingi, S.; Fontaine, R. H.
10.1101/2020.11.13.381061 — cell biology — Posted on 2020-11-14
2267 Properdin oligomers adopt rigid extended conformations supporting function
Pedersen, D. V.; Pedersen, M. N.; Mazarakis, S. M.; Wang, Y.; Lindorff-Larsen, K.; Arleth, L.; Andersen, G. R.
10.1101/2020.11.13.381772 — immunology — Posted on 2020-11-14
2268 Schizophrenia and autism-associated mutations and disrupted m6A signal by YTHDF1 cause defects in microtubule function and neurodevelopment
Roy, R.; Li, X.; Hou, S.; Fujiwara, Y.; Sukegawa, M.; Hong, W.-T.; Oomoto, I.; Ito, H.; Joshi, K.; Fan, R.; Nagata, K.-i.; Lai, K.-o.; Wang, D. O.
10.1101/2020.11.14.382556 — neuroscience — Posted on 2020-11-14
2270 Nutritional status and fecundity are synchronised by muscular exopheresis
Turek, M.; Piechota, M.; Banasiak, K.; Shanmugam, N.; Macias, M.; Sliwinska, M. A.; Niklewicz, M.; Kowalski, K.; Nowak, N.; Chacinska, A.; Pokrzywa, W.
10.1101/2020.06.17.157230 — physiology — Posted on 2020-11-14
2273 Global gene expression analysis of Streptococcus agalactiae at exponential growth phase
Silvestre, I.; Borges, V.; Duarte, S.; Nunes, A.; Sobral, R.; Vieira, L.; Gomes, J. P.; Borrego, M. J.
10.1101/2020.11.13.381939 — genomics — Posted on 2020-11-14
2276 EVALUATION OF ANTIMICROBIAL AND ANTIPROLIFERATIVE ACTIVITIES OF ACTINOBACTERIA ISOLATED FROM THE SALINE LAGOONS OF NORTHWEST PERU
Flores Clavo, R.; Ruiz Quinones, N.; Tasca Hernandez, A.; Tasca Gois Ruiz, A. L.; de Oliveira Braga, L. E.; Arce Gil, Z. L.; Serquen Lopez, L. M.; Henrique Costa, J.; Pacheco Fill, T.; Jose Salvador, M.; Fantinatti Garboggini, F.
10.1101/2020.10.07.329441 — molecular biology — Posted on 2020-11-14
2278 Functional pathway redundancy in the metabolism of plant-derived phenolics by Novosphingobium aromaticivorans
Perez, J. M.; Kontur, W. S.; Gehl, C.; Gille, D. M.; Ma, Y.; Niles, A. V.; Umana, G.; Donohue, T. J.; Noguera, D. R.
10.1101/2020.11.13.382549 — microbiology — Posted on 2020-11-14
2279 The two formyl peptide receptors differently regulate GPR84-mediated neutrophil NADPH-oxidase activity
Martensson, J.; Sundqvist, M.; Manandhar, A.; Ieremias, L.; Linjie, L.; Ulven, T.; Xie, X.; Bjorkman, L.; Forsman, H.
10.1101/2020.11.13.381582 — immunology — Posted on 2020-11-14
2281 Variations of intracellular density during the cell cycle arises from tip-growth regulation in fission yeast
Odermatt, P. D.; Miettinen, T. P.; Kang, J. H.; Bostan, E.; Manalis, S.; Huang, K. C.; Chang, F.
10.1101/2020.10.21.349696 — biophysics — Posted on 2020-11-14
2284 Metabolically-Driven Maturation of hiPSC-Cell Derived Heart-on-a-Chip
Huebsch, N.; Charrez, B.; Siemons, B.; Boggess, S. C.; Wall, S.; Neiman, G.; Charwat, V.; Jaeger, K.; Montiel, F. L. T.; Jeffreys, N. C.; Deveshwar, N.; Edwards, A.; Serrano, J.; Snuderl, M.; Stahl, A.; Tveito, A.; Miller, E. W.; Healy, K. E.
10.1101/485169 — bioengineering — Posted on 2020-11-14
2286 Skewed X inactivation in genetically diverse mice is associated with recurrent copy number changes at the Xce locus
Sun, K. Y.; Oreper, D. G.; Schoenrock, S. A.; McMullan, R.; Giusti-Rodriguez, P.; Zhabotynsky, V.; Miller, D. R.; Tarantino, L. M.; Pardo-Manuel de Villena, F.; Valdar, W.
10.1101/2020.11.13.380535 — genetics — Posted on 2020-11-14
2290 Smad3 Regulates Smooth Muscle Cell Fate and Governs Adverse Remodeling and Calcification of Atherosclerotic Plaque
Cheng, P.; Wirka, r.; Kim, J.; Nguyen, T.; Kundu, R.; Zhao, q.; Pedroza, A.; Nagao, M.; Iyer, D.; Fischbein, M.; Quertermous, T.
10.1101/2020.09.15.299131 — cell biology — Posted on 2020-11-14
2291 Differences in Activation of Intracellular Signalling in Primary Human Retinal Endothelial Cells Between Isoforms of VEGFA-165.
Dailey, W.; Schunemann, R.; Yang, F.; Moore, M.; Knapp, A.; Chen, P.; Deshpande, M.; Metcalf, B.; Tompkins, Q.; Guzman, A. E.; Felisky, J.; Mitton, K. P.
10.1101/2019.12.12.871947 — cell biology — Posted on 2020-11-14
2292 High Throughput RNA Sequencing of Germ- Free Mouse Retina Reveals Metabolic Pathways Involved in the Gut-Retina Axis
Nadeem, U.; Xie, B.; Movahedan, A.; D'Souza, M.; Barba, H.; Deng, N.; Leonne, V.; Chang, E. B.; Sulakhe, D.; Skondra, D.
10.1101/2020.10.01.318949 — molecular biology — Posted on 2020-11-14
2293 A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of infective endocarditis
Gaytan, M. O.; Singh, A. K.; Woodiga, S. A.; Patel, S. A.; An, S.-S.; Vera Ponce de Leon, A.; McGrath, S.; Miller, A. R.; Bush, J. M.; van der Linden, M.; Magrini, V.; Wilson, R. K.; Kitten, T.; King, S. J.
10.1101/2020.07.17.206995 — microbiology — Posted on 2020-11-14
2297 Hierarchical motor adaptations negotiate failures during force field learning
Ikegami, T.; Ganesh, G.; Gibo, T. L.; Yoshioka, T.; Osu, R.; Kawato, M.
10.1101/2020.07.16.207084 — neuroscience — Posted on 2020-11-14
2302 Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1
Tsai, P.-Y.; Lee, M.-S.; Jadhav, U.; Naqvi, I.; Madha, S.; Adler, A.; Mistry, M.; Naumenko, S.; Lewis, C. A.; Hitchcock, D. S.; Roberts, F. R.; DelNero, P.; Hank, T.; Honselmann, K. C.; Morales Oyarvide, V.; Mino-Kenudson, M.; Clish, C. B.; Shivdasani, R. A.; Kalaany, N. Y.
10.1101/2020.02.16.951681 — cancer biology — Posted on 2020-11-14
2311 Lateral and longitudinal fish eDNA distribution in dynamic riverine habitats
Thalinger, B.; Kirschner, D.; Putz, Y.; Moritz, C.; Schwarzenberger, R.; Wanzenboeck, J.; Traugott, M.
10.1101/2020.05.28.120147 — ecology — Posted on 2020-11-14
2312 The Nab2 RNA binding protein promotes sex-specific splicing of Sex lethal in Drosophila neuronal tissue
Jalloh, B.; Rounds, J. C.; Brown, B.; Kremsky, I.; Banerjee, A.; Morton, D. J.; Bienkowski, R.; Fasken, M. B.; Corbett, A. H.; Moberg, K. H.
10.1101/2020.11.13.382168 — developmental biology — Posted on 2020-11-14
2314 Lipid-specific protein oligomerization is regulated by two interfaces in Marburg virus matrix protein VP40
Amiar, S.; Husby, M. L.; Wijesinghe, K. J.; Angel, S.; Bhattarai, N.; Gerstman, B. S.; Chapagain, P. P.; Li, S.; Stahelin, R. V.
10.1101/2020.11.13.381350 — microbiology — Posted on 2020-11-14
2315 Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype
Guha, R.; Mathioudaki, A.; Doumbo, S.; Doumtabe, D.; Skinner, J.; Arora, G.; Siddiqui, S.; Li, S.; Kayentao, K.; Ongoiba, A.; Zaugg, J. B.; Traore, B.; Crompton, P. D.
10.1101/2020.10.21.346197 — immunology — Posted on 2020-11-14
2316 Antisense oligonucleotide therapy for KCNT1 encephalopathy
Burbano, L. E.; Li, M.; Jancovsky, N.; Jafar-Nejad, P.; Richards, K.; Sedo, A.; Soriano, A.; Rollo, B.; Jia, L.; Gazina, E.; Piltz, S.; Adikusuma, F.; Thomas, P. Q.; Rigo, F.; Reid, C. A.; Maljevic, S.; Petrou, S.
10.1101/2020.11.12.379164 — neuroscience — Posted on 2020-11-14
2319 A metabolic coincidence mechanism controls winter photoperiodism in plants
Liu, W.; Feke, A.; Leung, C. C.; Tarte, D.; Yuan, W.; Vanderwall, M.; Sager, G. C.; Wu, X.; Schear, A.; Clark, D.; Thines, B. C.; Gendron, J.
10.1101/2020.11.13.381426 — plant biology — Posted on 2020-11-14
2322 Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury
Redd, M.; Scheuer, S.; Saez, N.; Yoshikawa, Y.; Chiu, H.; Gao, L.; Hicks, M.; Villanueva, J.; Cuellar-Partida, G.; Peart, J.; See Hoe, L.; Chen, X.; Sun, Y.; Suen, J.; Hatch, R.; Rollo, B.; Alzubaidi, M.; Maljevic, S.; Qaiffe-Ryan, G. A.; Hudson, J. E.; Porrello, E.; White, M.; Cordwell, S.; Fraser, J.; Petrou, S.; Reichelt, M.; Thomas, W.; King, G.; MacDonald, P.; Palpant, N.
10.1101/869826 — physiology — Posted on 2020-11-14
2323 The solution structures of higher-order human telomere G-quadruplex multimers
Monsen, R. C.; Chakravarthy, S.; Dean, W. L.; Chaires, J. B.; Trent, J. O.
10.1101/2020.11.13.382036 — biophysics — Posted on 2020-11-14
2326 BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome
Fursova, N. A.; Turberfield, A. H.; Blackledge, N. P.; Findlater, E. L.; Lastuvkova, A.; Huseyin, M. K.; Dobrinic, P.; Klose, R. J.
10.1101/2020.11.13.381251 — molecular biology — Posted on 2020-11-14
2327 Common virulence gene expression in naive and severe malaria cases
Wichers, J. S.; Tonkin-Hill, G.; Thye, T.; Krumkamp, R.; Strauss, J.; von Thien, H.; Kreuels, B.; Scholz, J. A. M.; Hansson, H. H.; Jensen, R. W.; Turner, L.; Lorenz, F.-R.; Schoellhorn, A.; Bruchhaus, I.; Tannich, E.; Fendel, R.; Otto, T. D.; Lavstsen, T.; Gilberger, T. W.; Duffy, M. F.; Bachmann, A.
10.1101/2020.11.13.381137 — molecular biology — Posted on 2020-11-14
2329 HIV-1 uncoating by release of viral cDNA from capsid-like structures in the nucleus of infected cells.
Müller, T. G.; Zila, V.; Peters, K.; Schifferdecker, S.; Stanic, M.; Lucic, B.; Laketa, V.; Lusic, M.; Müller, B.; Kräusslich, H.-G.
10.1101/2020.11.13.380030 — microbiology — Posted on 2020-11-14
2330 Cellular and immunological mechanisms mediate reservoir host specialization by genotypically variable microparasites
Lin, Y.-P.; Tufts, D. M.; Dupuis, A. P.; Combs, M.; Marcinkiewicz, A. L.; Hirsbrunner, A. D.; Diaz, A. J.; Stout, J. L.; Blom, A. M.; Strle, K.; Davis, A. D.; Kramer, L. D.; Diuk-Wasser, M. A.
10.1101/2020.11.13.380550 — microbiology — Posted on 2020-11-14
2332 ILRUN downregulates ACE2 expression and blocks infection of human cells by SARS-CoV-2
Tribolet, L.; Alexander, M.; Brice, A.; Jansen Van Vuren, P.; Rootes, C.; Mara, K.; McDonald, M.; Bruce, K.; Gough, T.; Shi, S.; Cowled, C.; Bean, A.; Stewart, C. R.
10.1101/2020.11.13.381343 — cell biology — Posted on 2020-11-13
2335 A Whole Virion Vaccine for COVID-19 Produced Via a Novel Inactivation Method: Results from Animal Challenge Model Studies
Ragan, I. K.; Hartson, L. M.; Dutt, T. S.; Obregon-Henao, A.; Maison, R. M.; Gordy, P.; Fox, A.; Karger, B. R.; Cross, S. T.; Kapuscinski, M. L.; Cooper, S. K.; Podell, B. K.; Stenglein, M. D.; Bowen, R. A.; Henao-Tamayo, M.; Goodrich, R.
10.1101/2020.11.13.381335 — immunology — Posted on 2020-11-13
2336 A Theory for the Emergence of Neocortical Network Architecture
Udvary, D.; Harth, P.; Macke, J. H.; Hege, H.-C.; de Kock, C. P. J.; Sakmann, B.; Oberlaender, M.
10.1101/2020.11.13.381087 — neuroscience — Posted on 2020-11-13
2344 Quantification of Brucella abortus population structure in a natural host
Fiebig, A.; Vrentas, C. E.; Le, T. M.; Huebner, M.; Boggiatto, P. M.; Olsen, S. C.; Crosson, S.
10.1101/2020.11.12.380766 — microbiology — Posted on 2020-11-13
2345 StrongestPath: a Cytoscape application for protein-protein interaction analysis
Mousavian, Z.; Khodabandeh, M.; Sharifi-Zarchi, A.; Nadafian, A.; Mahmoudi, A.
10.1101/2020.11.12.380600 — systems biology — Posted on 2020-11-13
2346 SeqPIP-2020: Sequence based Protein InteractionPrediction Contest
Halder, A. K.; Mollah, A. F.; Chatterjee, P.; Kole, D. K.; Basu, S.; Plewczynski, D.
10.1101/2020.11.12.380774 — bioinformatics — Posted on 2020-11-13
2349 Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy
Agarwala, S.; Kim, K.-Y.; Phan, S.; Ju, S.; Kong, Y. E.; Castillon, G. A.; Bushong, E. A.; Ellisman, M. H.; Tamplin, O. J.
10.1101/2020.11.12.380790 — developmental biology — Posted on 2020-11-13
2350 Flexible fitting of PROTAC concentration-response curves with Gaussian Processes
Semenova, E.; Guerriero, M. L.; Zhang, B.; Hock, A.; Hopcroft, P.; Kadamur, G.; Afzal, A. M.; Lazic, S. E.
10.1101/2020.11.13.379883 — cell biology — Posted on 2020-11-13
2353 Accumbens D2-MSN hyperactivity drives behavioral supersensitivity
Kruyer, A.; Parilla-Carerro, J.; Powell, C.; Brandt, L.; Gutwinski, S.; Angelis, A.; Chalhoub, R.; Amato, D.
10.1101/2020.11.12.380667 — neuroscience — Posted on 2020-11-13
2356 Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology
Gai, W.; Zhou, Z.; Agbor-Enoh, S.; Fan, X.; Lian, S.; Jiang, P.; Cheng, S. H.; Wong, J.; Chan, S. L.; Jang, M. K.; Yang, Y.; Liang, R. H. S.; Chan, W. K.; Ma, E. S. K.; Leung, T. Y.; Chiu, R. W. K.; Valantine, H.; Chan, K. C. A.; Lo, Y. M. D.
10.1101/2020.11.13.381178 — physiology — Posted on 2020-11-13
2360 Automatic wound detection and size estimation using deep learning algorithms
Carrion, H.; Jafari, M.; Bagood, M. D.; Yang, H.-y.; Isseroff, R. R.; Gomez, M.
10.1101/2020.11.13.275917 — bioinformatics — Posted on 2020-11-13
2363 Electrical Stimulation Of The Cervical Dorsal Roots Enables Functional Arm And Hand Movements In Monkeys With Cervical Spinal Cord Injury
Barra, B.; Conti, S.; Perich, M. G.; Zhuang, K.; Schiavone, G.; Fallegger, F.; Galan, K.; James, N.; Barraud, Q.; Delacombaz, M.; Kaeser, M.; Rouiller, E. M.; Milekovic, T.; Lacour, S.; Bloch, J.; Courtine, G.; Capogrosso, M.
10.1101/2020.11.13.379750 — bioengineering — Posted on 2020-11-13
2364 A model of resource partitioning between foraging bees
Dubois, T.; Pasquaretta, C.; Barron, A.; Gautrais, J.; Lihoreau, M.
10.1101/2020.11.13.381012 — animal behavior and cognition — Posted on 2020-11-13
2369 Genetic variation at the Cyp6m2 putative insecticide resistance locus in Anopheles gambiae and Anopheles coluzzii
Wagah, M. G.; Korlevic, P.; Clarkson, C.; Miles, A.; The Anopheles gambiae 1000 Genomes Consortium, ; Lawniczak, M. K. N.; Makunin, A.
10.1101/2020.11.12.378943 — genetics — Posted on 2020-11-13
2370 Polygenic transcriptome risk scores improve portability of polygenic risk scores across ancestries
Liang, Y.; Pividori, M.; Manichaikul, A.; Palmer, A. A.; Cox, N. J.; Wheeler, H. E.; Im, H. K.
10.1101/2020.11.12.373647 — genetics — Posted on 2020-11-13
2371 Genome-wide association studies reveal the complex genetic architecture of DMI fungicide resistance in Cercospora beticola
Spanner, R.; Taliadoros, D.; Richards, J.; Rivera-Varas, V.; Neubauer, J.; Natwick, M.; Hamilton, O.; Vaghefi, N.; Pethybridge, S.; Secor, G. A.; Friesen, T. L.; Stukenbrock, E. H.; Bolton, M. D.
10.1101/2020.11.12.379818 — evolutionary biology — Posted on 2020-11-13
2374 Ten-year projection of white-nose syndrome disease dynamics at the southern leading-edge of infection in North America
Meierhofer, M. B.; Lilley, T. M.; Ruokolainen, L.; Johnson, J. S.; Parratt, S. R.; Morrison, M. L.; Pierce, B. L.; Evans, J. W.; Anttila, J.
10.1101/2020.11.12.379271 — ecology — Posted on 2020-11-13
2376 Developmental Single-cell transcriptomics in the Lytechinus variegatus 1 Sea Urchin Embryo
Massri, A. J.; Greenstreet, L.; Afanassiev, A.; Escobar, A. B.; Wray, G. M.; Schiebinger, G.; McClay, D. R.
10.1101/2020.11.12.380675 — developmental biology — Posted on 2020-11-13
2377 Contemplative mental training reduces hair glucocorticoid levels in a randomized clinical trial
Puhlmann, L.; Vrticka, P.; Linz, R.; Stalder, T.; Kirschbaum, C.; Engert, V.; Singer, T.
10.1101/2020.11.13.381038 — molecular biology — Posted on 2020-11-13
2378 Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system
Yablokov, E.; Sushko, T.; Kaluzhskiy, L.; Kavaleuski, A.; Mezentsev, Y.; Ershov, P.; Gilep, A.; Ivanov, A.; Strushkevich, N.
10.1101/2020.11.13.381095 — molecular biology — Posted on 2020-11-13
2379 Sex-specific lipid profiles in muscle of Atlantic salmon juveniles
House, A. H.; Primmer, C. R.; Debes, P. V.; Erkinaro, J.; Kakela, R.; Kurko, J.
10.1101/2020.11.13.379321 — molecular biology — Posted on 2020-11-13
2381 Rhipicephalus microplus and its vector-borne haemoparasites in Guinea: further species expansion in West Africa
Makenov, M. T.; Toure, A. H.; Korneev, M. G.; Sacko, N.; Porshakov, A. M.; Yakovlev, S. A.; Radyuk, E. V.; Zakharov, K. S.; Shipovalov, A. V.; Boumbaly, S.; Zhurenkova, O. B.; Grigoreva, Y. E.; Morozkin, E. S.; Fyodorova, M. V.; Karan, L. S.; Boiro, M. Y.
10.1101/2020.11.12.376426 — zoology — Posted on 2020-11-13
2382 Micromanipulation of amyloplasts with optical tweezers in Arabidopsis stems
Abe, Y.; Meguriya, K.; Matsuzaki, T.; Sugiyama, T.; Y. Yoshikawa, H.; Terao Morita, M.; Toyota, M.
10.1101/2020.11.12.379289 — plant biology — Posted on 2020-11-13
2386 Large-scale monitoring of resistance to coumaphos, amitraz and pyrethroids in Varroa destructor
Hernandez-Rodriguez, C. S.; Calatayud, F.; Mahiques, M. J.; Mompo, A.; Segura, I.; Simo, E.; Gonzalez-Cabrera, J.
10.1101/2020.11.12.378190 — pharmacology and toxicology — Posted on 2020-11-13
2388 Characterization of LC-MS based urine metabolomics in healthy subjects across the life span
Sun, W.; Liu, X.; Shi, Q.; Sun, H.; Li, J.; Tang, X.; Guo, Z.; Liu, Y.; Ma, J.; Ren, N.; Jin, F.; He, C.; Song, W.
10.1101/2020.11.12.379131 — biochemistry — Posted on 2020-11-13
2391 Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2
Clark, S. A.; Clark, L. E.; Pan, J.; Coscia, A.; McKay, L. G. A.; Shankar, S.; Johnson, R. I.; Griffiths, A.; Abraham, J.
10.1101/2020.11.13.381533 — microbiology — Posted on 2020-11-13
2393 In Vitro Activity of Itraconazole Against SARS-CoV-2
Van Damme, E.; De Meyer, S.; Bojkova, D.; Ciesek, S.; Cinatl, J.; De Jonghe, S.; Jochmans, D.; Leyssen, P.; Buyck, C.; Neyts, J.; Van Loock, M.
10.1101/2020.11.13.381194 — pharmacology and toxicology — Posted on 2020-11-13
2394 Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2
Rochman, N. D.; Wolf, Y. I.; Faure, G.; Zhang, F.; Koonin, E. V.
10.1101/2020.10.12.336644 — microbiology — Posted on 2020-11-13
2395 The effect of temperature and humidity on the stability of SARS-CoV-2 and other enveloped viruses
Morris, D. H.; Yinda, K. C. H.; Gamble, A.; Rossine, F. W.; Huang, Q.; Bushmaker, T.; Fischer, R. J.; Matson, M. J.; van Doremalen, N.; Vikesland, P. J.; Marr, L. C.; Munster, V.; Lloyd-Smith, J. O.
10.1101/2020.10.16.341883 — microbiology — Posted on 2020-11-13
2396 Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes
Karki, R.; Sharma, B. R.; Tuladhar, S.; Williams, E. P.; Zalduondo, L.; Samir, P.; Zheng, M.; Sundaram, B.; Banoth, B.; Malireddi, R. K. S.; Schreiner, P.; Neale, G.; Vogel, P.; Webby, R.; Jonsson, C. B.; Kanneganti, T.-D.
10.1101/2020.10.29.361048 — immunology — Posted on 2020-11-13
2400 Homemade Bread: Repurposing an Ancient Technology for Low Cost in vitro Tissue Engineering
Holmes, J. T.; Jaberansari, Z.; Collins, W.; Leblanc Latour, M.; Modulevsky, D. J.; Pelling, A.
10.1101/2020.11.13.353698 — bioengineering — Posted on 2020-11-13
2401 Polycomb Repressive Complex 2-controlled Essrg regulates intestinal Microfold cell differentiation.
George, J. J.; Oittinen, M.; Diaz, L. M.; Zapilko, V.; Iqbal, S.; Rintakangas, T.; Martins, F. T. A.; Niskanen, H.; Katajisto, P.; Kaikkonen, M. U.; Viiri, K.
10.1101/2020.11.13.379610 — molecular biology — Posted on 2020-11-13
2402 Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
Inoue, Y.; Nikolic, A.; Farnsworth, D.; Liu, A.; Ladanyi, M.; Somwar, R.; Gallo, M.; Lockwood, W.
10.1101/2020.11.12.368522 — cancer biology — Posted on 2020-11-13
2403 Streptococcus suis induces expression of cyclooxygenase-2 in porcine lung tissue
Dresen, M.; Schenk, J.; Berhanu Weldearegay, Y.; Vötsch, D.; Baumgärtner, W.; Valentin-Weigand, P.; Nerlich, A.
10.1101/2020.11.10.371575 — microbiology — Posted on 2020-11-13
2404 Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives
Bohutinska, M.; Vlcek, J.; Yair, S.; Leanen, B.; Konecna, V.; Fracassetti, M.; Slotte, T.; Kolar, F.
10.1101/2020.03.24.005397 — evolutionary biology — Posted on 2020-11-13
2405 Intraspecific diversity loss in a predator species alters prey community structure and ecosystem functions
Raffard, A.; Cucherousset, J.; Montoya, J. M.; Richard, M.; Acoca-Pidolle, S.; Poesy, C.; Garreau, A.; Santoul, F.; Blanchet, S.
10.1101/2020.06.10.144337 — ecology — Posted on 2020-11-13
2406 Analysis of Hippocampal Subfields in Sickle Cell Disease Using Ultrahigh Field MRI
Santini, T.; Koo, M.; Farhat, N.; Campos, V. P.; Alkhateeb, S.; Vieira, M. A. C.; Butters, M. A.; Rosano, C.; Aizenstein, H. J.; Mettenburg, J.; Novelli, E. M.; Ibrahim, T. S.
10.1101/2020.11.10.377564 — neuroscience — Posted on 2020-11-13
2411 Nucleotide-resolution bacterial pan-genomics with reference graphs
Colquhoun, R. M.; Hall, M. B.; Lima, L.; Roberts, L. W.; Malone, K. M.; Hunt, M.; Letcher, B.; Hawkey, J.; George, S.; Pankhurst, L.; Iqbal, Z.
10.1101/2020.11.12.380378 — bioinformatics — Posted on 2020-11-13
2412 Genetic landscape of recessive diseases in the Vietnamese population from large-scale clinical exome sequencing
Tran, N. H.; Nguyen Thi, T.-H.; Tang, H.-S.; Hoang, L.-P.; Nguyen, T.-H. L.; Tran, N.-T.; Trinh, T.-H. N.; Nguyen, V. T.; Nguyen, B.-H. H.; Nguyen, H. T.; Doan, L. P.; Phan, N.-M.; Nguyen, K.-H. T.; Nguyen, H.-D. L.; Quach, M.-T. T.; Nguyen, T.-P. T.; Tran, V. U.; Tran, D.-V.; Nguyen, Q.-T. T.; Do, T.-T. T.; Lam, N. V.; Cao Thi Ngoc, P.; Truong, D. K.; Nguyen, H.-N.; Phan, M.-D.; Giang, H.
10.1101/2020.10.27.358358 — genetics — Posted on 2020-11-13
2414 A Multiplexed Bacterial Two-Hybrid for Rapid Characterization of Protein-Protein Interactions and Iterative Protein Design
Boldridge, W. C.; Ljubetic, A.; Kim, H.; Lubock, N.; Szilagyi, D.; Lee, J.; Brodnik, A.; Jerala, R.; Kosuri, S.
10.1101/2020.11.12.377184 — molecular biology — Posted on 2020-11-13
2416 Unique Evolution of Antiviral Tetherin in Bats
Hayward, J. A.; Tachedjian, M.; Johnson, A.; Irving, A. T.; Gordon, T. B.; Cui, J.; Nicolas, A.; Smith, I.; Boyd, V.; Marsh, G. A.; Baker, M. L.; Wang, L.-F.; Tachedjian, G.
10.1101/2020.04.08.031203 — evolutionary biology — Posted on 2020-11-12
2417 High-throughput generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes
Shin, U.; Nakhro, K.; Oh, C.-K.; Carrington, B.; Song, H.; Varshney, G. K.; Kim, Y.; Song, H.; Jeon, S.; Robbins, G.; Kim, S.; Yoon, S.; Choi, Y.; Park, S.; Kim, Y. J.; Burgess, S. M.; Kang, S.; Sood, R.; Lee, Y.; Myung, K.
10.1101/2020.10.04.325621 — developmental biology — Posted on 2020-11-12
2420 Maternal RND3/RhoE deficiency impairs placental mitochondrial function in preeclampsia by modulating PPARγ-UCP2 cascade
Huang, L.; Ma, Y.; Chen, L.; Chang, J.; Zhong, M.; Wang, Z.; Sun, Y.; Chen, X.; Sun, F.; Xiao, L.; Chen, J.; Lai, Y.; Yan, C.; Yue, X.
10.1101/2020.06.22.164921 — pathology — Posted on 2020-11-12
2422 Morphology and immunhistchemical characteristics of the otic ganglion in chinchilla (Chinchila laniger Molina).
Sienkiewicz, W.; Kuchinka, J.; Dudek, A.; Nowak, E.; Kaleczyc, J.; Radzimirska, M.; Szczurkowski, A.
10.1101/2020.11.12.379503 — neuroscience — Posted on 2020-11-12
2423 Deleting Mecp2 from the entire cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice
Achilly, N. P.; He, L.; Kim, O. A.; Ohmae, S.; Wojaczynski, G. J.; Lin, T.; Sillitoe, R. V.; Medina, J. F.; Zoghbi, H. Y.
10.1101/2020.11.12.380162 — neuroscience — Posted on 2020-11-12
2430 Effects of additional load at different heights on gait initiation: a statistical parametric mapping of center of pressure and center of mass behavior
Vieira, M. F.; Rodrigues, F. B.; de Oliveira Assis, A.; de Mendonca Mesquita, E.; Lemes, T. S.; De Villa, G. A. G.; Baptista, R. R.; de Oliveira Andrade, A.; Lobo da Costa, P. H.
10.1101/2020.11.12.380261 — bioengineering — Posted on 2020-11-12
2431 ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replication
Qu, Y.; Wang, X.; Zhu, Y.; Wang, Y.; Yang, X.; Hu, G.; Liu, C.; Li, J.; Ren, S.; Xiao, Z.; Liu, Z.; Wang, W.; Li, P.; Zhang, R.; Liang, Q.
10.1101/2020.11.12.380709 — microbiology — Posted on 2020-11-12
2432 A practical PPE decontamination method using warm air and ambient humidity
Kwiek, J. J.; Pickett, C. R.; Flanigan, C. A.; Lee, M. V.; Saif, L. J.; Jahnes, J.; Blonder, G.
10.1101/2020.11.12.380196 — microbiology — Posted on 2020-11-12
2434 POINT Technology Illuminates The Processing Of Polymerase-Associated Intact Nascent Transcripts
Sousa-Luis, R.; Dujardin, G.; Zukher, I.; Kimura, H.; Carmo-Fonseca, M.; Proudfoot, N.; Nojima, T.
10.1101/2020.11.09.374108 — genomics — Posted on 2020-11-12
2436 A streamlined workflow for automated cryo focused ion beam milling
Tacke, S.; Erdmann, P.; Wang, Z.; Klumpe, S.; Grange, M.; Plitzko, J.; Raunser, S.
10.1101/2020.02.24.963033 — molecular biology — Posted on 2020-11-12
2438 Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection
Sundaramoorthy, E.; Ryan, A. P.; Fulzele, A.; Leonard, M.; Daugherty, M. D.; Bennett, E. J.
10.1101/2020.11.12.380634 — molecular biology — Posted on 2020-11-12
2439 The chemotherapeutic drug methotrexate selects for antibiotic resistance
Guthmundsdottir, J. S.; Fredheim, E. G. A.; Koumans, C. I. M.; Hegstad, J.; Tang, P.-C.; Andersson, D. I.; Samuelsen, O.; Johnsen, P. J.
10.1101/2020.11.12.378059 — microbiology — Posted on 2020-11-12
2447 Structure and lipid dynamics in the A. baumannii maintenance of lipid asymmetry (MLA) inner membrane complex
Mann, D.; Fan, J.; Farrell, D.; Somboon, K.; Muenks, A.; Tzokov, S.; Khalid, S.; DiMaio, F.; Miller, S.; Bergeron, J.
10.1101/2020.05.30.125013 — biochemistry — Posted on 2020-11-12
2451 Negative density-dependent parasitism in a group-living carnivore
Albery, G. F.; Newman, C.; Bright Ross, J. G.; MacDonald, D. W.; Bansal, S.; Buesching, C. D.
10.1101/2020.06.15.153726 — ecology — Posted on 2020-11-12
2452 Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
Tzani, I.; Herrmann, N.; Carillo, S.; Spargo, C. A.; Hagan, R.; Barron, N.; Bones, J.; Dillmore, W. S.; Clarke, C.
10.1101/2020.11.04.368480 — cell biology — Posted on 2020-11-12
2453 Mitochondrial profiling reveals dynamic, sex- and age-specific mitochondrial phenotypes in human immune cell subtypes
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2020-11-12
2455 Western Kenyan Anopheles gambiae s.s. showing intense permethrin resistance harbor distinct microbiota
Omoke, D.; Kipsum, M.; Otieno, S.; Esalimba, E.; Sheth, M.; Lenhart, A.; Njeru, E. M.; Ochomo, E.; Dada, N.
10.1101/2020.11.12.378760 — molecular biology — Posted on 2020-11-12
2456 Morc3 silences endogenous retroviruses by enabling Daxx-mediated H3.3 incorporation
Groh, S.; Milton, A. V.; Marinelli, L.; Sickinger, C. V.; Bollig, H.; de Almeida, G. P.; Schmidt, A.; Forne, I.; Imhof, A.; Schotta, G.
10.1101/2020.11.12.380204 — molecular biology — Posted on 2020-11-12
2457 Structure of the molecular bushing of the bacterial flagellar motor
Yamaguchi, T.; Makino, F.; Miyata, T.; Minamino, T.; Kato, T.; Namba, K.
10.1101/2020.11.12.379347 — molecular biology — Posted on 2020-11-12
2458 New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids
Ettayebi, K.; Tenge, V. R.; Cortes-Penfield, N. W.; Crawford, S. E.; Neill, F. H.; Zeng, X.-L.; Yu, X.; Ayyar, V. B.; Burrin, D.; Ramani, S.; Atmar, R. L.; Estes, M. K.
10.1101/2020.11.12.380022 — microbiology — Posted on 2020-11-12
2459 Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD
Mehedi, M.; Osan, J. K.; Talukdar, S. N.; Feldmann, F.; DeMontigny, B. A.; Jerome, K.; Bailey, K. L.; Feldmann, H.
10.1101/2020.11.11.379099 — microbiology — Posted on 2020-11-12
2461 High-fat diet-induced activation of SGK1 promotes Alzheimer's disease-associated tau pathology
Elahi, M.; Motoi, Y.; Shimonaka, S.; Ishida, Y.; Hioki, H.; Takanashi, M.; Ishiguro, K.; Imai, Y.; Hattori, N.
10.1101/2020.05.14.095471 — neuroscience — Posted on 2020-11-12
2463 Single-cell RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates and humans
Bakken, T. E.; van Velthoven, C. T. J.; Menon, V.; Hodge, R. D.; Yao, Z.; Nguyen, T. N.; Graybuck, L. T.; Horwitz, G. D.; Bertagnolli, D.; Goldy, J.; Garren, E.; Parry, S.; Casper, T.; Shehata, S. I.; Barkan, E. R.; Szafer, A.; Levi, B. P.; Dee, N.; Smith, K. A.; Sunkin, S. M.; Bernard, A.; Phillips, J. W.; Hawrylycz, M.; Koch, C.; Murphy, G.; Lein, E.; Zeng, H.; Tasic, B.
10.1101/2020.11.05.367482 — neuroscience — Posted on 2020-11-12
2465 Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease
Guenther, S.; Reinke, P. Y. A.; Fernandez-Garcia, Y.; Lieske, J.; Lane, T. J.; Ginn, H.; Koua, F.; Ehrt, C.; Ewert, W.; Oberthuer, D.; Yefanov, O.; Meier, S.; Lorenzen, K.; Krichel, B.; Kopicki, J.; Gelisio, L.; Brehm, W.; Dunkel, I.; Seychell, B.; Gieseler, H.; Norton-Baker, B.; Escudero-Perez, B.; Domaracky, M.; Saouane, S.; Tolstikova, A.; White, T.; Haenle, A.; Groessler, M.; Fleckenstein, H.; Trost, F.; Galchenkova, M.; Gevorkov, Y.; Li, C.; Awel, S.; Peck, A.; Barthelmess, M.; Schluenzen, F.; Lourdu, X. P.; Werner, N.; Andaleeb, H.; Ullah, N.; Falke, S.; Srinivasan, V.; Franca, B.; Schwi
10.1101/2020.11.12.378422 — biophysics — Posted on 2020-11-12
2468 Nucleotide-resolution bacterial pan-genomics with reference graphs
Colquhoun, R. M.; Hall, M. B.; Lima, L.; Roberts, L. W.; Malone, K. M.; Hunt, M.; Letcher, B.; Hawkey, J.; George, S.; Pankhurst, L.; Iqbal, Z.
10.1101/2020.11.12.380378 — bioinformatics — Posted on 2020-11-12
2471 Fluorescent Antibody Multiplexing with Oligo-Based Combinatorial Labeling
McCarthy, M.; Anglin, C.; Pear, H.; Boleman, S.; Klaubert, S.; Birtwistle, M. R.
10.1101/2020.11.06.371906 — biochemistry — Posted on 2020-11-12
2473 Shapes and Genescapes: Mapping Multivariate Phenotype-Biological Process Associations for Craniofacial Shape
Aponte, J. D.; Katz, D. C.; Liu, W.; Andrade, F.; Roseman, C. C.; Murray, S. A.; Cheverud, J.; Marcucio, R.; Hallgrimsson, B.
10.1101/2020.11.12.378513 — genomics — Posted on 2020-11-12
2474 What's left in the tank? Identification of non-ascribed aquarium's coral collections with DNA barcodes as part of an integrated diagnostic approach
Colin, L.; Abed-Navandi, D.; A. Conde, D.; Craggs, J.; da Silva, R.; Janse, M.; Källström, B.; Pearce-Kelly, A.; yesson, C.
10.1101/2020.07.15.202739 — genetics — Posted on 2020-11-12
2475 Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras
Kazandjian, T. D.; Petras, D.; Robinson, S. D.; van Thiel, J.; Greene, H. W.; Arbuckle, K.; Barlow, A.; Carter, D. A.; Wouters, R. M.; Whiteley, G.; Wagstaff, S. C.; Arias, A. S.; Albulescu, L.-O.; von Plettenberg Laing, A.; Hall, C.; Heap, A.; Penrhyn-Lowe, S.; McCabe, C. V.; Ainsworth, S.; da Silva, R. R.; Dorrestein, P. C.; Richardson, M. K.; Gutierrez, J. M.; Calvete, J. J.; Harrison, R. A.; Vetter, I.; Undheim, E. A. B.; Wüster, W.; Casewell, N. R.
10.1101/2020.07.08.192443 — evolutionary biology — Posted on 2020-11-12
2476 Phylodynamic analysis of an emergent Mycobacterium bovis outbreak in an area with no previously known wildlife infections
Rossi, G.; Crispell, J.; Brough, T.; Lycett, S. J.; White, P. C. L.; Allen, A.; Ellis, R. J.; Gordon, S. V.; Harwood, R.; Palkopoulou, E.; Presho, E.; Skuce, R.; Smith, G. C.; Kao, R. R.
10.1101/2020.11.12.379297 — ecology — Posted on 2020-11-12
2478 Extended spectrum β-lactamase and carbapenemase genes are substantially and sequentially reduced during conveyance and treatment of urban sewage
Li, L.; Nesme, J.; Quintela-Baluja, M.; Balboa, S.; Hashsham, S.; Williams, M. R.; Yu, Z.; Sorensen, S. J.; Graham, D. W.; Romalde, J. L.; Dechesne, A.; Smets, B. F.
10.1101/2020.11.12.379032 — ecology — Posted on 2020-11-12
2480 SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
Scarborough, A. M.; Flaherty, J. N.; Hunter, O. V.; Liu, K.; Kumar, A.; Xing, C.; Tu, B. P.; Conrad, N. K.
10.1101/2020.11.12.380626 — molecular biology — Posted on 2020-11-12
2483 Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies
Caillat, C.; Guilligay, D.; Torralba, J.; Friedrich, N.; Nieva, J. L.; Trkola, A.; Chipot, C.; Dehez, F.; Weissenhorn, W.
10.1101/2020.11.12.379396 — microbiology — Posted on 2020-11-12
2484 Neuraminidase inhibitors rewire neutrophil function in murine sepsis and COVID-19 patient cells
Formiga, R. O.; Amaral, F. C.; Souza, C. F.; Mendes, D. A. G. B.; Wanderley, C. W. S.; Lorenzini, C. B.; Santos, A. A.; Antonia, J.; Faria, L. F.; Natale, C. C.; Paula, N. M.; Silva, P. C. S.; Fonseca, F. R.; Aires, L.; Heck, N.; Barroso, S. P. C.; Morrot, A.; Sordi, R.; Alisson-Silva, F.; Mansur, D. S.; Cunha, F. Q.; Maurici, R.; Bafica, A.; Macauley, M. S.; Spiller, F.
10.1101/2020.11.12.379115 — immunology — Posted on 2020-11-12
2485 ACE2-Targeting Monoclonal Antibody As A "Pan" Coronavirus Blocker In Vitro and In A Mouse Model
Chen, Y.; Zhang, Y.; Yan, R.; Wang, G.; Zhang, Y.; Zhang, Z.; Li, Y.; Chu, W.; Chen, Y.; Chen, G.; Wang, Q.; Zhou, Q.; Zhang, B.; Wang, C.
10.1101/2020.11.11.375972 — immunology — Posted on 2020-11-12
2488 Mycobacteria-host interactions in human bronchiolar airway organoids
Iakobachvili, N.; Leon Icaza, S. A.; Knoops, K.; Sachs, N.; Mazeres, S.; Simeone, R.; Peixoto, A.; Murris-Espin, M.; Mazieres, J.; Lopez-Iglesias, C.; Ravelli, R. B. G.; Neyrolles, O.; Meunier, E.; Lugo-Villarino, G.; Clevers, H.; Cougoule, C.; Peters, P. J.
10.1101/2020.11.12.379586 — systems biology — Posted on 2020-11-12
2491 The repurposed drugs suramin and quinacrine inhibit cooperatively in vitro SARS-CoV-2 3CLpro
Eberle, R. J.; Olivier, D. S.; Amaral, M. S.; Willbold, D.; Arni, R. K.; Coronado, M. A.
10.1101/2020.11.11.378018 — biochemistry — Posted on 2020-11-12
2493 A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
Celik, H.; Krug, E.; Zhang, C. R.; Han, W.; Issa, N.; Koh, W. K.; Bjeije, H.; Kukhar, O.; Allen, M.; Li, T.; Fisher, D. A.; Fowles, J.; Wong, T. N.; Stubbs, M. C.; Koblish, H. K.; Oh, S. T.; Challen, G. A.
10.1101/2020.11.12.378810 — cancer biology — Posted on 2020-11-12
2498 A Recombinant Protein Biomarker DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins
Ahn, S. B.; Kamath, K. S.; Mohamedali, A.; Noor, Z.; Wu, J. X.; Pascovici, D.; Adhikari, S.; Cheruku, H. R.; Guillemin, G. J.; McKay, M. J.; Nice, E. C.; Baker, M. S.
10.1101/2020.11.11.377309 — biochemistry — Posted on 2020-11-12
2501 Multi-Modal Profiling of Human Fetal Liver-Derived Hematopoietic Stem Cells Reveals the Molecular Signature of Engraftment Potential
Vanuytsel, K.; Villacorta-Martin, C.; Lindstrom-Vautrin, J.; Wang, Z.; Garcia-Beltran, W. F.; Vrbanac, V.; Matte, T. M.; Dowrey, T. W.; Kumar, S. S.; Li, M.; Dries, R.; Campbell, J. D.; Belkina, A. C.; Balazs, A. B.; Murphy, G. J.
10.1101/2020.11.11.378620 — cell biology — Posted on 2020-11-12
2502 Visual processing speed is linked to functional connectivity between right frontoparietal and visual networks
Küchenhoff, S.; Sorg, C.; Schneider, S.; Kohl, O.; Müller, H. J.; Finke, K.; Ruiz-Rizzo, A. L.
10.1101/2020.11.11.378406 — neuroscience — Posted on 2020-11-12
2505 Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health
Marabita, F.; James, T.; Karhu, A.; Mills, R.; Perheentupa, T.; Stenlund, H.; Boulund, F.; Hellström, C.; Neiman, M.; Virtanen, H.; Kettunen, K.; Laivuori, H.; Helkkula, P.; Byrne, M.; Honko, H.; Kallonen, A.; Ermes, M.; Similä, H.; Lindholm, M.; Widen, E.; Ripatti, S.; Perälä-Heape, M.; Engstrand, L.; Nilsson, P.; Moritz, T.; Miettinen, T.; Sallinen, R.; Kallioniemi, O.
10.1101/2020.11.11.365387 — systems biology — Posted on 2020-11-12
2510 Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2
Araujo, T. S.; Scapin, S. M.; Andrade, W.; Fasciotti, M.; de Magalhaes, M. T.; Almeida, M. S.; Lima, L. M. T. d. R.
10.1101/2020.11.11.379065 — biophysics — Posted on 2020-11-12
2511 Frustration in protein complexes leads to interaction versatility
Freiberger, M. I.; Wolynes, P. G.; Ferreiro, D. U.; Fuxreiter, M.
10.1101/2020.11.11.378091 — bioinformatics — Posted on 2020-11-12
2513 TIGA: Target illumination GWAS analytics
Yang, J. J.; Grissa, D.; Lambert, C. G.; Bologa, C. G.; Mathias, S. L.; Waller, A.; Wild, D. J.; Jensen, L. J.; Oprea, T. I.
10.1101/2020.11.11.378596 — bioinformatics — Posted on 2020-11-12
2517 Multilevel Twin Models: Geographical Region as a Third Level Variable
Tamimy, Z.; Kevenaar, S. T.; Hottenga, J. J.; Hunter, M. D.; de Zeeuw, E. L.; Neale, M. C.; van Beijsterveldt, C. E. M.; Dolan, C. V.; van Bergen, E.; Boomsma, D. I.
10.1101/2020.11.11.377820 — genetics — Posted on 2020-11-12
2525 Conformational dynamics regulate SHANK3 actin and Rap1 binding
Salomaa, S. I.; Miihkinen, M.; Kremneva, E.; Paatero, I.; Lilja, J.; Jacquemet, G.; Vuorio, J.; Antenucci, L.; Hassani-Nia, F.; Hollos, P.; Isomursu, A.; Vattulainen, I.; Coffey, E. T.; Kreienkamp, H.-J.; Lappalainen, P.; Ivaska, J.
10.1101/2020.11.12.379222 — cell biology — Posted on 2020-11-12
2527 Transcriptome Analysis of NPFR Neurons Reveals a Connection Between proteome Diversity and Social Behavior
Ryvkin, J.; Bentzur, A.; Shmueli, A.; Tennenbaum, M.; Shallom, O.; Dokarker, S.; Levi, M.; Shohat-Ophir, G.
10.1101/2020.11.12.379826 — neuroscience — Posted on 2020-11-12
2528 The Spatial Memory Pipeline: a model of egocentric to allocentric understanding in mammalian brains
Uria, B.; Ibarz, B.; Banino, A.; Zambaldi, V.; Kumaran, D.; Hassabis, D.; Barry, C.; Blundell, C.
10.1101/2020.11.11.378141 — neuroscience — Posted on 2020-11-12
2529 Full activation of an α7-α3β4 nicotinic receptor complex decreases desensitization receptor in human chromaffin cells
Jimenez-Pompa, A.; Sanz-Lazaro, S.; Medina-Polo, J.; Gonzalez-Enguita, C.; Blazquez, J.; McIntosh, J. M.; Albillos, A.
10.1101/2020.11.11.360537 — neuroscience — Posted on 2020-11-12
2531 VGLUT modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration
Buck, S. A.; Steinkellner, T.; Aslanoglou, D.; Villeneuve, M.; Bhatte, S. H.; Childers, V. C.; Rubin, S. A.; De Miranda, B. R.; O'Leary, E. I.; Neureiter, E. G.; Fogle, K. J.; Palladino, M. J.; Logan, R. W.; Glausier, J. R.; Fish, K. N.; Lewis, D. A.; Greenamyre, J. T.; Bonci, A.; McCabe, B. D.; Cheetham, C. E.; Hnasko, T. S.; Freyberg, Z.
10.1101/2020.11.11.379008 — neuroscience — Posted on 2020-11-12
2532 Distinct brain mechanisms linked to evidence accumulation and crime-type bias in juror decisions
Castrellon, J. J.; Hakimi, S.; Parelman, J. M.; Yin, L.; Law, J. R.; Skene, J. A. G.; Ball, D. A.; Malekpour, A.; Beskind, D. H.; Vidmar, N.; Pearson, J. M.; Skene, J. H. P.; Carter, R. M.
10.1101/2020.11.11.378935 — neuroscience — Posted on 2020-11-12
2536 Tracing the evolution of aneuploid cancers from multiregional sequencing
Chattopadhyay, S.; Karlsson, J.; Valind, A.; Andersson, N.; Gisselsson, D.
10.1101/2020.11.11.376467 — bioinformatics — Posted on 2020-11-12
2539 Pangenome-based genome inference
Ebler, J.; Clarke, W. E.; Rausch, T.; Audano, P. A.; Houwaart, T.; Korbel, J.; Eichler, E. E.; Zody, M. C.; Dilthey, A. T.; Marschall, T.
10.1101/2020.11.11.378133 — bioinformatics — Posted on 2020-11-12
2544 Comprehensive dataset of shotgun metagenomes from stratified freshwater lakes and ponds
Buck, M.; Garcia, S. L.; Fernandez Vidal, L.; Martin, G.; Martinez Rodriguez, G. A.; Saarenheimo, J.; Zopfi, J.; Bertilsson, S.; Peura, S.
10.1101/2020.11.12.379446 — ecology — Posted on 2020-11-12
2545 Dynamic Domain Specificity In Human Ventral Temporal Cortex
Bankson, B. B.; Boring, M. J.; Richardson, R. M.; Ghuman, A. S.
10.1101/2020.11.11.378877 — neuroscience — Posted on 2020-11-12
2546 Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs
Brighi, C.; Salaris, F.; Soloperto, A.; Cordella, F.; Ghirga, S.; de Turris, V.; Rosito, M.; Porceddu, P. F.; Reggiani, A.; Rosa, A.; Di Angelantonio, S.
10.1101/2020.11.12.379800 — neuroscience — Posted on 2020-11-12
2550 Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu
Goods, B. A.; Askenase, M. H.; Markarian, E.; Beatty, H. E.; Drake, R.; Fleming, I.; DeLong, J. H.; Philip, N. H.; Matouk, C. C.; Awad, I. A.; Zuccarello, M.; Hanley, D. F.; Love, J. C.; Shalek, A. K.; Sansing, L. H.
10.1101/2020.11.10.375675 — immunology — Posted on 2020-11-12
2551 Chirality-dependent anti-inflammatory effect of glutathione after spinal cord injury
Kim, S. J.; Ko, W.-K.; Han, G. H.; Lee, D.; Lee, Y.; Sheen, S. H.; Hong, J. B.; Sohn, S.
10.1101/2020.11.11.377721 — neuroscience — Posted on 2020-11-12
2553 The effect of pre-resection obesity on post-resection body composition after 75% small bowel resection in rats
Patel, N. S.; Yanala, U. R.; Aravind, S.; Reidelberger, R. D.; Thompson, J. S.; Carlson, M. A.
10.1101/2020.11.11.377945 — physiology — Posted on 2020-11-12
2556 A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.
McCann, A. J.; Lou, J.; Moustaqil, M.; Blum, A.; Fontaine, F.; Liu, H.; Luu, W.; Koopman, P.; Sierecki, E.; Gambin, Y.; Meunier, F. A.; Liu, Z.; Hinde, E.; Francois, M.
10.1101/2020.11.11.378968 — cell biology — Posted on 2020-11-12
2559 Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R
Dankovich, T. M.; Kaushik, R.; Cassinelli Petersen, G.; Giro, P. E.; Abdul Hadi, H.; Bao, G.; Beuermann, S.; Cooper, B. H.; Dityatev, A.; Rizzoli, S. O.
10.1101/2020.11.11.377515 — neuroscience — Posted on 2020-11-12
2560 Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes
Paulsen, B.; Velasco, S.; Kedaigle, A. J.; Pigoni, M.; Quadrato, G.; Deo, A.; Adiconis, X.; Uzquiano, A.; Kim, K.; Simmons, S. K.; Tsafou, K.; Albanese, A.; Sartore, R.; Abbate, C.; Tucewicz, A.; Smith, S.; Chung, K.; Lage, K.; Regev, A.; Levin, J. Z.; Arlotta, P.
10.1101/2020.11.10.376509 — developmental biology — Posted on 2020-11-12
2562 ERAP2 facilitates a subpeptidome of Birdshot Uveitis-associated HLA-A29
Venema, W.; Hiddingh, S.; de Boer, J. H.; Claas, F.; Mulder, A.; Hollander, A. D.; Stratikos, E.; Sarkizova, S.; Veken, L. v. d.; Janssen, G.; Veelen, P. v.; Kuiper, J. J.
10.1101/2020.08.14.250654 — immunology — Posted on 2020-11-12
2563 Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
Ordonez, L. D.; Melchor, L.; Greenow, K. R.; Kendrick, H.; Tornillo, G.; Bradford, J.; Giles, P.; Smalley, M. J.
10.1101/2020.10.30.361998 — cancer biology — Posted on 2020-11-12
2564 Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids
Valle-Encinas, E.; Aleksieva, N.; Velasco Martinez, C.; Dawes, M.; Zverev, M.; Muller, M.; Offergeld, A.; Smalley, M. J.; Hogan, C.; Forbes, S. J.; Bird, T. G.; Dale, T. C.
10.1101/2020.11.09.374462 — cell biology — Posted on 2020-11-12
2565 Task specialization across research careers
Robinson-Garcia, N.; Costas, R.; Sugimoto, C. R.; Lariviere, V.; Nane, G. F.
10.1101/2020.07.01.181669 — scientific communication and education — Posted on 2020-11-12
2569 Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics
Gordillo-Maranon, M.; Zwierzyna, M.; Charoen, P.; Drenos, F.; Chopade, S.; Shah, T.; Engmann, J.; Casas, J.-P.; Chaturvedi, N.; Papacosta, O.; Wannamethee, G.; Wong, A.; Sofat, R.; Kivimaki, M.; Price, J. F.; Hughes, A. D.; Gaunt, T. R.; Lawlor, D. A.; Gaulton, A.; Hingorani, A. D.; Schmidt, A. F.; Finan, C.
10.1101/2020.11.11.377747 — genetics — Posted on 2020-11-11
2570 Distinct molecular signatures of fission predict mitochondrial degradation or proliferation
Kleele, T.; Rey, T.; Winter, J.; Zaganelli, S.; Mahecic, D.; Perreten Lambert, H.; Ruberto, F.; Nemir, M.; Wai, T.; Pedrazzini, T.; Manley, S.
10.1101/2020.11.11.372557 — cell biology — Posted on 2020-11-11
2571 FcγR responses to soluble immune complexes of varying size: A scalable cell-based reporter system
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2020-11-11
2572 Neurons in the dorso-central division of zebrafish pallium respond to change in visual numerosity
Messina, A.; Potrich, D.; Schiona, I.; Sovrano, V. A.; Fraser, S. E.; Brennan, C. H.; Vallortigara, G.
10.1101/2020.11.11.377804 — neuroscience — Posted on 2020-11-11
2573 Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Edwards, R. J.; Field, M. A. J.; Ferguson, J. M.; Dudchenko, O.; Keilwagen, J.; Rosen, B. D.; Johnson, G. S.; Rice, E.; Hillier, L.; Hammond, J. M.; Tomwarnicki, S. G.; Omer, A.; Skvortsova, K.; Bogdanovic, O.; Zammit, R. A.; Aiden, E. L.; Warren, W. C.; Ballard, J. W. O.
10.1101/2020.11.11.379073 — genomics — Posted on 2020-11-11
2574 Default Mode Network Ventral Hub Connectivity Associated with Memory Impairment in Temporal Lobe Epilepsy Surgery
Neal, E.; Di, L.; Park, Y. J.; Finch, A.; Korneli, F.; Maciver, S.; Bezchlibnyk, Y. B.; Schoenberg, M. R.; Vale, F. L.
10.1101/2020.11.11.377929 — neuroscience — Posted on 2020-11-11
2575 Structure and variability of optogenetic responses identify the operating regime of cortex
Palmigiano, A.; Fumarola, F.; Mossing, D. P.; Kraynyukova, N.; Adesnik, H.; Miller, K.
10.1101/2020.11.11.378729 — neuroscience — Posted on 2020-11-11
2585 Human PRE-PIK3C2B exhibits long-range intra- and inter-chromosomal interactions with genomic regions enriched in repressive marks.
Maini, J.; Pathak, A. K.; Bhattacharyya, K.; Kumar, N.; Narang, A.; Jain, N.; Singh, I.; Dhingra, V.; Brahmachari, V.
10.1101/2020.11.11.378745 — genetics — Posted on 2020-11-11
2586 In vitro evaluation of the response of human tendon-derived stromal cells to a novel electrospun suture for tendon repair
Nezhentsev, A.; Abhari, R. E.; Baldwin, M. J.; Mimpen, J. Y.; Augustyniak, E.; Isaacs, M.; Mouthuy, P.-A.; Carr, A. J.; Snelling, S. J.
10.1101/2020.11.11.378695 — cell biology — Posted on 2020-11-11
2588 Electrotrophy as potential primary metabolism for colonization of conductive surfaces in deep-sea hydrothermal chimneys
PILLOT, G.; Davidson, S.; Shintu, L.; Amin Ali, O.; Godfroy, A.; Combet-Blanc, Y.; Bonin, P.; Liebgott, P.-P.
10.1101/2020.11.11.377697 — microbiology — Posted on 2020-11-11
2589 Quantitative metaproteomics of patient fecal microbiota identifies host and microbial proteins associated with ulcerative colitis
Thuy-Boun, P. S.; Wang, A. Y.; Crissien-Martinez, A.; Xu, J. H.; Chatterjee, S.; Stupp, G. S.; Su, A. I.; Coyle, W. J.; Wolan, D. W.
10.1101/2020.11.11.378836 — microbiology — Posted on 2020-11-11
2590 Seafloor incubation experiment with deep-sea hydrothermal vent fluid reveals effect of pressureand lag time on autotrophic microbial communities
Fortunato, C. S.; Butterfield, D. A.; Larson, B.; Lawrence-Slavas, N.; Algar, C.; Allen, L. Z.; Holden, J. F.; Proskurowski, G.; Reddington, E.; Stewart, L. C.; Topcuoglu, B. D.; Vallino, J. J.; Huber, J. A.
10.1101/2020.11.11.378315 — microbiology — Posted on 2020-11-11
2591 The Palmitoyl Acyltransferase ZDHHC14 Controls Kv1-Family Potassium Channel Clustering at the Axon Initial Segment
Sanders, S. S.; Hernandez, L. M.; Soh, H.; Karnam, S.; Walikonis, R. S.; Tzingounis, A.; Thomas, G. M.
10.1101/2020.11.11.378240 — neuroscience — Posted on 2020-11-11
2594 A functional pre-screening platform for identifying points of vulnerability in the cell death map of human melanoma tumors
Dekel-Bird, N. P.; Bialik, S.; Itzhaki, O.; Salame, T. M.; Yaeli-Slonim, N.; Levin-Salomon, V.; Dasari, S. K.; Besser, M.; Kimchi, A.
10.1101/2020.11.11.377671 — cancer biology — Posted on 2020-11-11
2596 The regulation of liver gene expression by carbohydrates is mouse strain specific
Chi, Y.; Youn, D. Y.; Xiaoli, A. M.; Liu, L.; Pessin, J. B.; Yang, F.; Pessin, J. E.
10.1101/2020.11.11.378497 — genomics — Posted on 2020-11-11
2601 Exposure to Airborne Bacteria Depends upon Vertical Stratification and Vegetation Complexity
Robinson, J. M.; Cando Dumancela, C.; Antwis, R. E.; Cameron, R.; Liddicoat, C.; Poudel, R.; Weinstein, P.; Breed, M. F.
10.1101/2020.11.11.377630 — ecology — Posted on 2020-11-11
2602 Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma
Prummel, K. D.; Crowell, H. L.; Nieuwenhuize, S.; Brombacher, E. C.; Daetwyler, S.; Soneson, C.; Kresoja-Rakic, J.; Ronner, M.; Kocere, A.; Ernst, A.; Labbaf, Z.; Clouthier, D. E.; Firulli, A. B.; Sanchez-Iranzo, H.; O'Rourke, R.; Raz, E.; Mercader, N.; Burger, A.; Felley-Bosco, E.; Huisken, J.; Robinson, M. D.; Mosimann, C.
10.1101/2020.11.11.355693 — developmental biology — Posted on 2020-11-11
2603 Force requirements of endocytic vesicle formation
Abella Guerra, M.; Andruck, L.; Malengo, G.; Skruzny, M.
10.1101/2020.11.11.378273 — cell biology — Posted on 2020-11-11
2604 Structure of the RPAP3:TRBP interaction reveals an involvement of the HSP90/R2TP chaperone complex in dsRNA pathways
ABEL, Y.; CHARRON, C.; BOURGUIGNON-IGEL, V.; QUINTERNET, M.; CHAGOT, M.-E.; VERHEGGEN, C.; BRANLANT, C.; BERTRAND, E.; MANIVAL, X.; CHARPENTIER, B.; REDERSTORFF, M.
10.1101/2020.11.11.367672 — molecular biology — Posted on 2020-11-11
2605 Nsp1 of SARS-CoV-2 Stimulates Host Translation Termination
Shuvalov, A.; Shuvalova, E.; Biziaev, N.; Sokolova, E.; Evmenov, K.; Egorova, T.; Alkalaeva, E.
10.1101/2020.11.11.377739 — molecular biology — Posted on 2020-11-11
2607 Long read metagenomics, the next step?
Haro-Moreno, J. M.; Lopez-Perez, M.; Rodriguez-Valera, F.
10.1101/2020.11.11.378109 — microbiology — Posted on 2020-11-11
2608 Synergism and antagonism of bacterial-viral co-infection in the upper respiratory tract
Manna, S.; McAuley, J.; Jacobson, J.; Nguyen, C. D.; Ullah, M. A.; Williamson, V.; Mulholland, E. K.; Wijburg, O.; Phipps, S.; Satzke, C.
10.1101/2020.11.11.378794 — microbiology — Posted on 2020-11-11
2609 Immune responses in pancreatic cancer may be restricted byprevalence of activated regulatory T-cells, dysfunctionalCD8+ T-cells, and senescent T-cells
Sivakumar, S.; Abu-Shah, E.; Ahern, D.; Arbe-Barnes, E. H.; Mangal, N.; Reddy, S.; Rendek, A.; Easton, A.; Kurz, E.; Silva, M.; Heij, L. R.; Soonawalla, Z.; Bashford-Rogers, R.; Middleton, M. R.; Dustin, M.
10.1101/2020.06.20.163071 — immunology — Posted on 2020-11-11
2614 Interactions between two QTLs for time to anthesis on spike development and fertility in wheat
Basavaraddi, P. A.; Savin, R.; Wingen, L.; Bencivenga, S.; Przewieslik-Allen, S.; Griffiths, S.; Slafer, G.
10.1101/2020.11.11.378208 — physiology — Posted on 2020-11-11
2615 ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin
Olsen, R. R.; Kastner, D. W.; Ireland, A. S.; Groves, S. M.; Pozo, K.; Whitney, C. P.; Guthrie, M. R.; Wait, S. J.; Soltero, D.; Witt, B. L.; Quaranta, V.; Johnson, J. E.; Oliver, T. G.
10.1101/2020.11.11.362632 — cancer biology — Posted on 2020-11-11
2619 Multistep mechanism of DNA replication-coupled G-quadruplex resolution
Sato, K.; Martin-Pintado, N.; Post, H.; Altelaar, M.; Knipscheer, P.
10.1101/2020.11.11.378067 — biochemistry — Posted on 2020-11-11
2620 Enzyme catalysis prior to aromatic residues: reverse engineering of a dephosphoCoA kinase
Makarov, M.; Meng, J.; Tretyachenko, V.; Srb, P.; Brezinova, A.; Giacobelli, V. G.; Bednarova, L.; Vondrasek, J.; Dunker, A. K.; Hlouchova, K.
10.1101/2020.11.11.377994 — biochemistry — Posted on 2020-11-11
2621 The structural basis of fatty acid elongation by the ELOVL elongases
Nie, L.; Pike, A. C.; Pascoa, T. C.; Bushell, S. R.; Quigley, A.; Ruda, G. F.; Chu, A.; Cole, V.; Speedman, D.; Moreira, T.; Shrestha, L.; Mukhopadhyay, S. M.; Burgess-Brown, N. A.; Love, J. D.; Brennan, P. E.; Carpenter, E. P.
10.1101/2020.11.11.378570 — biochemistry — Posted on 2020-11-11
2622 Structure of the Human Signal Peptidase Complex Reveals the Determinants for Signal Peptide Cleavage
Liaci, A. M.; Steigenberger, B.; Tamara, S.; Telles de Souza, P. C.; Grollers-Mulderij, M.; Ogrissek, P.; Marrink, S.-J.; Scheltema, R. A.; Foerster, F.
10.1101/2020.11.11.378711 — biochemistry — Posted on 2020-11-11
2623 Manipulation of a cation-{Pi} sandwich reveals conformational flexibility in phenylalanine hydroxylase
Arturo, E. C.; Merkel, G.; Hansen, M. R.; Lisowski, S.; Almeida, D.; Gupta, K.; Jaffe, E. K.
10.1101/2020.02.28.969873 — biochemistry — Posted on 2020-11-11
2626 A FGF2-mediated incoherent feedforward loop inducesErk inhibition and promotes naive pluripotency
Gharibi, B.; Goncalves, E.; Nashun, B.; Montoya, A.; Mankalow, K.; Strohbuecker, S.; Malik Sheriff, R. S.; Cicarrelli, A.; Carvalho, J.; Nye, E.; Kramer, H.; Rosewell, I.; Hajkova, P.; Beltrao, P.; Santos, S.
10.1101/2020.11.11.378869 — developmental biology — Posted on 2020-11-11
2628 An Entropic Safety Catch Controls Hepatitis C Virus Entry and Antibody Resistance.
Stejskal, L.; Kalemera, M. D.; Palor, M.; Walker, L.; Daviter, T.; Lees, W. D.; Moss, D. S.; Kremyda-Vlachou, M.; Kozlakidis, Z.; Rosenberg, W.; Illingworth, C. J. R.; Shepherd, A. J.; Grove, J.
10.1101/2020.11.11.377218 — molecular biology — Posted on 2020-11-11
2629 Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
Sun, S.; Gu, H.; Cao, L.; Chen, Q.; Yang, G.; Li, R.-T.; Fan, H.; Ye, Q.; Deng, Y.-Q.; Song, X.; Qi, Y.; Li, M.; Lan, J.; Feng, R.; Wang, L.; Zhang, Y.; Zhou, C.; Zhao, L.; Chen, Y.; Shen, M.; Cui, Y.; Yang, X.; Wang, X.; Wang, H.; Wang, X.; Qin, C.
10.1101/2020.11.10.377333 — microbiology — Posted on 2020-11-11
2631 Non-Invasive Plasma Glycomic and Metabolic Biomarkers of Post-treatment Control of HIV
Giron, L. B.; Palmer, C. S.; Yin, X.; Emmanouil, P.; Damra, M.; Goldman, A. R.; Tang, H. Y.; Johnston, R.; Mounzer, K.; Kostman, J. R.; Tebas, P.; Landay, A.; Montaner, L. J.; Jacobson, J. M.; Li, J.; Abdel-Mohsen, M.
10.1101/2020.11.11.378174 — microbiology — Posted on 2020-11-11
2632 Interferon receptor-deficient mice are susceptible to eschar-associated rickettsiosis.
Burke, T. P.; Engstrom, P.; Tran, C. J.; Glasner, D. R.; Espinosa, D. A.; Harris, E.; Welch, M. D.
10.1101/2020.09.23.310409 — microbiology — Posted on 2020-11-11
2636 Rapid generation of potent antibodies by autonomous hypermutation in yeast
Wellner, A.; McMahon, C.; Gilman, M. S. A.; Clements, J. R.; Clark, S.; Nguyen, K. M.; Ho, M. H.; Shin, J.-E.; Feldman, J.; Hauser, B. M.; Caradonna, T. M.; Wingler, L. M.; Schmidt, A. G.; Marks, D. S.; Abraham, J.; Kruse, A. C.; Liu, C. C.
10.1101/2020.11.11.378778 — bioengineering — Posted on 2020-11-11
2637 Stapled peptides based on Human Angiotensin-Converting Enzyme 2 (ACE2) potently inhibit SARS-CoV-2 infection in vitro
Curreli, F.; Victor, S. M. B.; Ahmed, S.; Drelich, A.; Tong, X.; Tseng, C.-T. K.; Hillyer, C. D.; Debnath, A. K.
10.1101/2020.08.25.266437 — pharmacology and toxicology — Posted on 2020-11-11
2639 Mobility and infectiousness in the spatial spread of an emerging fungal pathogen
Langwig, K. E.; White, J. P.; Parise, K. L.; Kaarakka, H. M.; Redell, J. A.; DePue, J. E.; Scullon, W. H.; Foster, J. T.; Kilpatrick, A. M.; Hoyt, J. R.
10.1101/2020.05.07.082651 — ecology — Posted on 2020-11-11
2641 Inositol pyrophosphate kinase (VIH2) impart drought resistance by promoting plant cell wall homeostasis
Shukla, A.; Kaur, M.; Kanwar, S.; Kaur, G.; Sharma, S.; Mazumder, K.; Pandey, P.; Rishi, V.; Pandey, A. K.
10.1101/743294 — plant biology — Posted on 2020-11-11
2646 Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression
Gao, P.; Lyu, Q.; Ghanam, A. R.; Lazzarotto, C. R.; Newby, G. A.; Zhang, W.; Choi, M.; Slivano, O. J.; Holden, K.; Walker, J. A.; Kadina, A. P.; Munroe, R. J.; Abratte, C. M.; Schimenti, J. C.; Liu, D. R.; Tsai, S. Q.; Long, X.; Miano, J. M.
10.1101/2020.11.07.372748 — genetics — Posted on 2020-11-11
2647 On the necessity of recurrent processing during object recognition: it depends on the need for scene segmentation
Seijdel, N.; Loke, J.; van de Klundert, R.; van der Meer, M.; Quispel, E.; van Gaal, S.; de Haan, E. H.; Scholte, H. S.
10.1101/2020.11.11.377655 — neuroscience — Posted on 2020-11-11
2651 A low-dimensional connectome manifold governs the organization and plasticity of social brain functions in humans.
Valk, S. L.; Kanske, P.; Park, B.-y.; Hong, S.-J.; Boeckler-Raettig, A.; Trautwein, F.-M.; Bernhardt, B. C.; Singer, T.
10.1101/2020.11.11.377895 — neuroscience — Posted on 2020-11-11
2653 The unfolded protein response links tumor aneuploidy to local immune dysregulation
Xian, S.; Searles, S. T.; Sahani, P.; Weller, T. C.; Jepsen, K.; Carter, H.; Zanetti, M.
10.1101/2020.11.10.377358 — cancer biology — Posted on 2020-11-11
2654 Building blocks of protein structures - Physics meets Biology
Skrbic, T.; Maritan, A.; Giacometti, A.; Rose, G. D.; Banavar, J. R.
10.1101/2020.11.10.375105 — biophysics — Posted on 2020-11-11
2655 accuEnhancer: Accurate enhancer prediction by integration of multiple cell type data with deep learning
Tung, Y.-A.; Yang, W.-T.; Hsieh, T.-T.; Chang, Y.-C.; Wu, J.-T.; Oyang, Y.-J.; Chen, C.-Y.
10.1101/2020.11.10.375717 — bioinformatics — Posted on 2020-11-11
2657 Precise Estimation of In Vivo Protein Turnover Rates
O'Brien, J.; Narayan, V.; Wong, Y. L.; Seitzer, P.; Sandoval, C.; Haste, N.; Smith, M.; Rad, R.; Gaun, A.; Baker, A.; Kukurugya, M.; Martin-McNulty, B.; Zhang, C.; Kolumam, G.; Sidrauski, C.; Jojic, V.; McAllister, F.; Bennett, B.; Buffenstein, R.
10.1101/2020.11.10.377440 — bioinformatics — Posted on 2020-11-11
2660 Engineered Prime Editors with PAM flexibility
Kweon, J.; Yoon, J.-K.; Jang, A.-H.; Shin, H. R.; See, J.-E.; Jang, G.; KIM, J.-I.; Kim, Y.
10.1101/2020.11.10.377580 — bioengineering — Posted on 2020-11-11
2662 Epigenome-wide study of brain DNA methylation among opioid users and controls
Shu, C.; Sosnowski, D. W.; Tao, R.; Deep-Soboslay, A.; Kleinman, J. E.; Hyde, T. M.; Jaffe, A. E.; Sabunciyan, S.; Maher, B. S.
10.1101/2020.11.10.377069 — genomics — Posted on 2020-11-11
2663 Long-read isoform sequencing reveals survival-associated splicing in breast cancer
Veiga, D. F. T.; Nesta, A.; Zhao, Y.; Deslattes Mays, A.; Huynh, R.; Rossi, R.; Wu, T.-C.; Palucka, K.; Anczukow, O.; Beck, C. R.; Banchereau, J.
10.1101/2020.11.10.376996 — genomics — Posted on 2020-11-11
2668 Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly
Chinen, T.; Yamazaki, K.; Hashimoto, K.; Fujii, K.; Watanabe, K.; Takeda, Y.; Yamamoto, S.; Nozaki, Y.; Tsuchiya, Y.; Takao, D.; Kitagawa, D.
10.1101/2020.11.10.377341 — cell biology — Posted on 2020-11-11
2671 Comparative genomic analyses provide clues to capsule switch in Streptococcus suis
Zhu, Y.; Dong, W.; Ma, J.; Zhang, Y.; Zhong, X.; Pan, Z.; Liu, G.; Wu, Z.; Yao, H.
10.1101/2020.11.11.377622 — microbiology — Posted on 2020-11-11
2674 The impact of exercise intensity on neurophysiological indices of food-related inhibitory control and cognitive control: A randomized crossover event-related potential (ERP) study
Bailey, B. W.; Muir, A. M.; Bartholomew, C. L.; Christensen, W. F.; Carbine, K. A.; Marsh, H.; LaCouture, H.; McCutcheon, C.; Larson, M. J.
10.1101/2020.11.10.377267 — neuroscience — Posted on 2020-11-11
2679 Analysis of Hippocampal Subfields in Sickle Cell Disease Using Ultrahigh Field MRI
Santini, T.; Koo, M.; Farhat, N.; Campos, V. P.; Alkhateeb, S.; Vieira, M. A. C.; Butters, M. A.; Rosano, C.; Aizenstein, H. J.; Mettenburg, J.; Novelli, E. M.; Ibrahim, T. S.
10.1101/2020.11.10.377564 — neuroscience — Posted on 2020-11-11
2683 Root system influence on high dimensional leaf phenotypes over the grapevine growing season
Harris, Z. N.; Klein, L. L.; Awale, M.; Swift, J. F.; Migicovsky, Z.; Bhakta, N.; Frawley, E.; Chitwood, D. H.; Fennell, A.; Kovacs, L. G.; Kwasniewski, M.; Londo, J. P.; Ma, Q.; Miller, A. J.
10.1101/2020.11.10.376947 — plant biology — Posted on 2020-11-11
2690 Intraoperative enrichment of bone autograft with autologous bone marrow-derived mononuclear cells isolated simultaneously: moving towards tissue engineering in situ
Baranovskii, D. S.; Akhmedov, B. G.; Krasilnikova, O. A.; Demchenko, A. G.; Krasheninnikov, M. E.; Balyasin, M. V.; Pavlova, O. Y.; Serova, N. S.; Klabukov, I. D.
10.1101/2020.11.09.375188 — bioengineering — Posted on 2020-11-11
2695 Potent neutralizing equine antibodies raised against recombinant SARS-CoV-2 spike protein for COVID-19 passive immunization therapy
Cunha, L. E. R.; Stolet, A. A.; Strauch, M. A.; Pereira, V. A. R.; Dumard, C. H.; Gomes, A. M. O.; Souza, P. N. C.; Fonseca, J. G.; Pontes, F. E.; Meirelles, L. G. R.; Albuquerque, J. W. M.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Lima, T. M.; Alvim, R. G. F.; Marsili, F. F.; Caldeira, M. M.; Higa, L. M.; Monteiro, F. L.; Zingali, R.; Oliveira, G. A. P.; Souza, T. M. L.; Tanuri, A.; Oliveira, A. C.; Guedes, H. L. M.; Castilho, L. R.; Silva, J. L.
10.1101/2020.08.17.254375 — immunology — Posted on 2020-11-11
2696 A reduced level of consciousness affects non-conscious processes
Fontan, A.; Lindgren, L.; Pedale, T.; Brorsson, C.; Bergstrom, F.; Eriksson, J.
10.1101/2020.11.10.376483 — neuroscience — Posted on 2020-11-11
2697 Neuroanatomical abnormalities in a nonhuman primate model of congenital Zika virus infection
Seelke, A.; Beckman, D.; Bennett, J.; Dougherty, P.; Van Rompay, K. K. A.; Keesler, R.; Pesavento, P. A.; Coffey, L. L.; Morrison, J. H.; Bliss-Moreau, E.
10.1101/2020.11.10.374611 — neuroscience — Posted on 2020-11-11
2699 Maternal nutritional stress alters sperm competence in male mice offspring leading to reduced fertility
Muranishi, Y.; Parry, L.; Vachette-dit-Martin, M.; Saez, F.; Coudy-Gandilhon, C.; Sauvanet, P.; Volle, D.; Tournayre, J.; Bottari, S.; Carpentiero, F.; Escoffier, J.; Bruhat, A.; Maurin, A.-C.; Averous, J.; Arnoult, C.; Fafournoux, P.; Jousse, C.
10.1101/2020.11.10.376616 — physiology — Posted on 2020-11-11
2700 Adipose Triglyceride Lipase is needed for homeostatic control of Sterol Element-Binding Protein-1c driven lipogenesis
Wieser, B. I.; Pena de la Sancha, P.; Schauer, S.; Reicher, H.; Sattler, W.; Breinbauer, R.; Schweiger, M.; Espenshade, P. J.; Zechner, R.; Hoefler, G.; Vesely, P. W.
10.1101/2020.11.02.363440 — biochemistry — Posted on 2020-11-11
2701 Viruses of the Thermotogota; the vehicles on the highways of gene sharing.
Haverkamp, T. H. A.; Lossouarn, J.; Zhaxybayeva, O.; Lyu, J.; Bienvenu, N.; Geslin, C.; Nesbo, C. L.
10.1101/2020.11.07.368316 — evolutionary biology — Posted on 2020-11-11
2704 A novel Hsp90 phospho-switch modulates virulence in the major human fungal pathogen Candida albicans
Diezmann, S.; Alaalm, L.; Crunden, J. L.; Butcher, M.; Obst, U.; Whealy, R.; Williamson, C. E.; O'Brien, H. E.; Schaffitzel, C.; Ramage, G.
10.1101/2020.09.23.309831 — microbiology — Posted on 2020-11-11
2706 Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma
De Crignis, E.; Romal, S.; Carofiglio, F.; Moulos, P.; Verstegen, M. M. A.; Khalid, M. M.; Pourfarzad, F.; Rao, S.; Bazrafshan, A.; Koutsothanassis, C.; Gehart, H.; Kan, T. W.; Palstra, R.-J.; Boucher, C.; IJzermans, J.; Huch, M.; Boj, S.; Vries, R.; Clevers, H.; van der Laan, L.; Hatzis, P.; Mahmoudi, T.
10.1101/568147 — cancer biology — Posted on 2020-11-11
2707 Making many out of few: deep generative models for single-cell RNA-sequencing data
Treppner, M.; Salas-Bastos, A.; Hess, M.; Lenz, S. M.; Vogel, T.; Binder, H.
10.1101/2020.05.27.119594 — bioinformatics — Posted on 2020-11-11
2708 Evolutionary divergence of novel open reading frames in cichlids speciation
Puntambekar, S.; Newhouse, R.; Navas, J. S. M.; Chauhan, R.; Vernaz, G.; Willis, T.; Wayland, M. T.; Umrania, Y.; Miska, E. A.; Prabakaran, S.
10.1101/2020.03.13.991182 — evolutionary biology — Posted on 2020-11-11
2710 "Self-inactivating" rabies viruses are susceptible to loss of their intended attenuating modification
Matsuyama, M.; Jin, L.; Lavin, T. K.; Sullivan, H. A.; Hou, Y.; Lea, N. E.; Pruner, M. T.; Dam Ferdinez, M. L.; Wickersham, I. R.
10.1101/550640 — neuroscience — Posted on 2020-11-11
2711 Sucrose represses the expression of the strigolactone signalling gene D3/RMS4/MAX2 to promote tillering
Patil, S. B.; Barbier, F. F.; Zhao, J.; Zafar, S. A.; Uzair, M.; Sun, Y.; Fang, J.; Bertheloot, J.; Sakr, S.; Fichtner, F.; Chabikwa, T. G.; Yuan, S.; Beveridge, C. A. A.; Li, X.
10.1101/2020.11.10.377549 — plant biology — Posted on 2020-11-11
2715 Mixed-stock analysis in the age of genomics: Rapture genotyping enables evaluation of stock-specific exploitation in a freshwater fish population with weak genetic structure
Euclide, P. T.; MacDougall, T.; Robinson, J. M.; Faust, M. D.; Wilson, C. C.; Chen, K.-Y.; Marschall, E. A.; Larson, W. A.; Ludsin, S. A.
10.1101/2020.11.10.376350 — genomics — Posted on 2020-11-11
2716 NyuWa Genome Resource: Deep Whole Genome Sequencing Based Chinese Population Variation Profile and Reference Panel
Zhang, P.; Luo, H.; Li, Y.; Wang, Y.; Wang, J.; Zheng, Y.; Niu, Y.; Shi, Y.; Zhou, H.; Song, T.; Kang, Q.; Xu, T.; He, S.
10.1101/2020.11.10.376574 — genomics — Posted on 2020-11-11
2718 Leprosy in wild chimpanzees
Hockings, K. J.; Mubemba, B.; Avanzi, C.; Pleh, K.; Dux, A.; Bersacola, E.; Bessa, J.; Ramon, M.; Metzger, S.; Patrono, L. V.; Jaffe, J. E.; Benjak, A.; Bonneaud, C. J.; Busso, P.; Couacy-Hymann, E.; Gado, M.; Gagneux, S.; Johnson, R. C.; Kodio, M.; Lynton-Jenkins, J. G.; Morozova, I.; Matz-Rensing, K.; Regalla, A.; Said, A. R.; Schuenemann, V. J.; Sow, S. O.; Spencer, J. S.; Ulrich, M.; Zoubi, H.; Cole, S. T.; Wittig, R.; Calvignac-Spencer, S.; Leendertz, F. H.
10.1101/2020.11.10.374371 — evolutionary biology — Posted on 2020-11-11
2719 Reduced Expression of Slc Genes in the VTA and NAcc of Male Mice with Positive Fighting Experience
Smagin, D. A.; Babenko, V. N.; Kovalenko, I. L.; Galyamina, A. G.; Redina, O. E.; Kudryavtseva, N. N.
10.1101/2020.11.10.377523 — neuroscience — Posted on 2020-11-11
2720 The Mechanical Roles of Chaperons
Haldar, S.; chaudhuri, D.; banerjee, s.; Chakraborty, S.
10.1101/2020.10.20.346973 — biophysics — Posted on 2020-11-11
2728 The Autism Risk Factor CHD8 Is a Chromatin Activator and Functionally Dependent on the ERK-MAPK Pathway Effector ELK1
HADDADDERAFSHI, B.; Danko, T.; Chanda, S.; Batista, P.; Litzenburger, U.; Lee, Q. Y.; Ng, Y. H.; Sebin, A.; Chang, H. Y.; Sudhof, T. C.; Wernig, M.
10.1101/2020.11.10.377010 — cell biology — Posted on 2020-11-10
2730 Coinfection of Streptococcus pneumoniae reduces airborne transmission of influenza virus
Mueller Brown, K.; Le Sage, V.; French, A. J.; Jones, J. E.; Padovani, G. H.; Avery, A. J.; Myerburg, M. M.; Schultz-Cherry, S.; Rosch, J. W.; Hiller, N. L.; Lakdawala, S. S.
10.1101/2020.11.10.376442 — microbiology — Posted on 2020-11-10
2741 High-throughput imaging of mRNA at the single-cell level in human primary immune cells
Gadkari, M.; Sun, J.; Carcamo, A.; Alessi, H.; Hu, Z.; Fraser, I. D. C.; Pegoraro, G.; Franco, L. M.
10.1101/2020.11.10.377283 — genomics — Posted on 2020-11-10
2743 Bispecific tau antibodies with additional binding to C1q or alpha-synuclein
Quint, W. H.; Matecko-Burmann, I.; Schilcher, I.; Loeffler, T.; Scholl, M.; Burmann, B. M.; Vogels, T.
10.1101/2020.11.10.376301 — neuroscience — Posted on 2020-11-10
2744 Spaceflight Affects Neuronal Morphology and Alters Transcellular Degradation of Neuronal Debris in Adult Caenorhabditis elegans
Laranjeiro, R.; Harinath, G.; Pollard, A. K.; Gaffney, C. J.; Deane, C. S.; Vanapalli, S. A.; Etheridge, T.; Szewczyk, N. J.; Driscoll, M.
10.1101/2020.11.10.377143 — neuroscience — Posted on 2020-11-10
2746 Engineering Radioprotective Human Cells Using the Tardigrade Damage Suppressor Protein, DSUP
Westover, C.; Najjar, D.; Meydan, C.; Grigorev, K.; Veling, M.; Chang, R.; Iosim, S.; Colon, R.; Yang, S.; Restrep, U.; Chin, C.; Butler, D.; Moszary, C.; Rahmatulloev, S.; Afshinnekoo, E.; Silver, P.; Mason, C.
10.1101/2020.11.10.373571 — synthetic biology — Posted on 2020-11-10
2752 Rapid evolution by clonal selection within populations of fibroblasts propagated on a novel soft substrate
Purkayastha, P.; Pendyala, K.; Saxena, A. S.; Hakimjavadi, H.; Chamala, S.; Dixit, P. D.; Baer, C. F.; Lele, T. P.
10.1101/2020.04.26.061911 — evolutionary biology — Posted on 2020-11-10
2757 Contractile reprogramming of cardiac pericytes by MEK inhibition promotes arteriologenesis of the ischemic heart
Avolio, E.; Katare, R.; Thomas, A. C.; Caporali, A.; Schwenke, D.; Meloni, M.; Caputo, M.; Madeddu, P.
10.1101/2020.11.10.376772 — cell biology — Posted on 2020-11-10
2759 SF3B1 promotes tumor malignancy through splicing-independent co-activation of HIF1α
Simmler, P.; Cortijo, C.; Koch, L. M.; Galliker, P.; Angori, S.; Bolck, H. A.; Mueller, C.; Vukolic, A.; Mirtschink, P.; Christinat, Y.; Davidson, N. R.; Lehmann, K.-V.; Pellegrini, G.; Pauli, C.; Lenggenhager, D.; Guccini, I.; Ringel, T.; Hirt, C.; Raetsch, G.; Moch, H.; Stoffel, M.; Schwank, G.
10.1101/2020.11.10.376780 — cell biology — Posted on 2020-11-10
2760 The role of cytosolic polyadenylation element binding protein 2 alternative splicing in hypoxia
Mayo, E. M.; Stevens, S. C.; Ali, A. N.; Moss, C. J.; Lund, S. P.; Nazario-Munoz, G. S.; Chalfant, C. E.; Park, M. A.
10.1101/2020.10.05.325290 — cell biology — Posted on 2020-11-10
2761 Scalable In Vitro Production of Defined Mouse Erythroblasts
Francis, H.; Harrold, C.; Beagrie, R.; King, A.; Gosden, M. E.; Blayney, J.; Jeziorska, D.; Babbs, C.; Higgs, D. R.; Kassouf, M.
10.1101/2020.11.10.376749 — molecular biology — Posted on 2020-11-10
2762 SARS-CoV-2 infection causes transient olfactory dysfunction in mice
Qin, C.-F.; Ye, Q.; Zhou, J.; Yang, G.; Li, R.-T.; He, Q.; Zhang, Y.; Wu, S.-J.; Chen, Q.; Shi, J.-H.; Zhang, R.-R.; Zhu, H.-M.; Qiu, H.-Y.; Zhang, T.; Deng, Y.-Q.; Li, X.-F.; Xu, P.; Yang, X.
10.1101/2020.11.10.376673 — microbiology — Posted on 2020-11-10
2763 Genetic Evidence for Selective Transfer of Microbes Between the International Space Station and an Astronaut
Danko, D. C.; Singh, N. K.; Butler, D. J.; Mozsary, C.; Jiang, P.; Keshavarzian, A.; Maienschein-Cline, M.; Chlipala, G.; Afshinnekoo, E.; Bezdan, D.; Garrett-Bakelman, F.; Green, S. J.; Turek, F. W.; Vitaterna, M. H.; Venkateswaran, K.; Mason, C. E.
10.1101/2020.11.10.376954 — microbiology — Posted on 2020-11-10
2764 Streptococcus suis induces expression of cyclooxygenase-2 in porcine lung tissue
Dresen, M.; Schenk, J.; Berhanu Weldearegay, Y.; Vötsch, D.; Baumgärtner, W.; Valentin-Weigand, P.; Nerlich, A.
10.1101/2020.11.10.371575 — microbiology — Posted on 2020-11-10
2766 Mapping Cognitive Brain Functions at Scale
Balasubramani, P. P.; Ojeda, A.; Grennan, G.; Maric, V.; Le, H.; Alim, F.; Zafar-Khan, M.; Diaz-Delgado, J.; Silveira, S.; Ramanathan, D.; Mishra, J.
10.1101/2020.05.14.097014 — neuroscience — Posted on 2020-11-10
2767 Synthesis and preclinical evaluation of MTP38 as a novel PET ligand for phophodiesterase 7 in the brain
Obokata, N.; Seki, C.; Hirata, T.; Maeda, J.; Ishii, H.; Nagai, Y.; Matsumura, T.; Takakuwa, M.; Fukuda, H.; Minamimoto, T.; Kawamura, K.; Zhang, M.-R.; Nakajima, T.; Saijo, T.; Higuchi, M.
10.1101/2020.10.29.354696 — neuroscience — Posted on 2020-11-10
2768 SorCS1 binds the insulin receptor to enhance insulin sensitivity
Kjolby, M.; Breining, P.; Pedersen, K. M.; Wellner, N.; Sorensen, K. M. J.; Vittrup, D. M.; Gjessing, A. M. P.; Januliene, D.; Manavalan, A.; Rotman, M.; Thotakura, G.; Skeldal, S.; Madsen, P.; Thirup, S.; Hermey, G.; Vaegter, C. B.; Moller, A.; Asplund, O.; Prasad, R.; Parlevliet, E.; Rensen, P. C. N.; Fuchtbauer, E.-M.; Madsen, A. N.; Holst, B.; Andersen, O. M.; Hansen, T.
10.1101/2020.11.10.376178 — physiology — Posted on 2020-11-10
2770 Docosahexaenoic acid significantly reduces tumor cell growth in preclinical models of ovarian cancer
Bilyk, O.; Hamedi, B.; Dutta, I.; Newell, M.; Bukhari, A. B.; Gamper, A. M.; McVea, R. C.; Liu, J.; Schueler, J.; Siegers, G. M.; Field, C. J.; Postovit, L.-M.
10.1101/2020.11.10.376152 — cancer biology — Posted on 2020-11-10
2772 4DNvestigator: Time Series Hi-C and RNA-seq DataAnalysis Toolbox
Lindsly, S. M.; Ronquist, S.; Lu, S.; Dilworth, S.; Perlman, M.; Rajapakse, I.
10.1101/2020.01.08.898387 — bioinformatics — Posted on 2020-11-10
2774 Highly potent bispecific sybodies neutralize SARS-CoV-2
Walter, J. D.; Hutter, C. A. J.; Garaeva, A. A.; Scherer, M.; Zimmermann, I.; Wyss, M.; Rheinberger, J.; Ruedin, Y.; Earp, J. C.; Egloff, P.; Sorgenfrei, M.; Hürlimann, L.; Gonda, I.; Meier, G.; Remm, S.; Thavarasah, S.; Zimmer, G.; Slotboom, D. J.; Paulino, C.; Plattet, P.; Seeger, M. A.
10.1101/2020.11.10.376822 — biochemistry — Posted on 2020-11-10
2777 ECM remodeling and spatial cell cycle coordination determine tissue growth kinetics
Ainslie, A. P.; Davis, J. R.; Williamson, J. J.; Ferreira, A.; Torres-Sanchez, A.; Hoppe, A.; Mangione, F.; Smith, M. B.; Martin-Blanco, E.; Salbreux, G.; Tapon, N.
10.1101/2020.11.10.376129 — developmental biology — Posted on 2020-11-10
2780 A polyglutamine domain is required for de novo CIZ1 assembly formation at the inactive X chromosome
Sofi, S.; Williamson, L.; Turvey, G. L.; Scoynes, C.; Hirst, C.; Godwin, J.; Brockdorff, N.; Ainscough, J.; Coverley, D.
10.1101/2020.11.10.376558 — cell biology — Posted on 2020-11-10
2782 Oligomeric hypercomplex of the complete oxidative phosphorylation system in heart mitochondria.
Nesterov, S. V.; Chesnokov, Y. M.; Kamyshinsky, R. A.; Panteleeva, A. A.; Lyamzaev, K. G.; Vasilov, R. G.; Yaguzhinsky, L. S.
10.1101/2020.08.17.253922 — molecular biology — Posted on 2020-11-10
2783 Benchmarking DNA isolation kits used in analyses of the urinary microbiome
Karstens, L.; Siddiqui, N. Y.; Zaza, T.; Barstad, A.; Amundsen, C. L.; Sysoeva, T. A.
10.1101/2020.11.10.375279 — microbiology — Posted on 2020-11-10
2785 Protective efficacy of a SARS-CoV-2 DNA Vaccine in wild-type and immunosuppressed Syrian hamsters
Brocato, R.; Kwilas, S. A.; Kim, R. K.; Zeng, X.; Principe, L. M.; Smith, J. M.; Hooper, J.
10.1101/2020.11.10.376905 — microbiology — Posted on 2020-11-10
2786 Strong influence of vertebrate host phylogeny on gut archaeal diversity
Youngblut, N. D.; Reischer, G. H.; Dauser, S.; Walzer, C.; Stalder, G.; Farnleitner, A. H.; Ley, R. E.
10.1101/2020.11.10.376293 — microbiology — Posted on 2020-11-10
2787 The hydroalcoholic extract of Uncaria tomentosa (Cat's claw) inhibits the replication of novel coronavirus (SARS-CoV-2) in vitro
Yepes-Perez, A. F.; Herrera-Calderon, O.; Florez-Alvarez, L.; Zapata-Cardona, M. I.; Yepes, L.; Aguilar, W.; Rugeles, M. T.; Zapata, W.
10.1101/2020.11.09.372201 — microbiology — Posted on 2020-11-10
2790 Comparison of three air samplers for the collection of four nebulized respiratory viruses
Kutter, J. S.; de Meulder, D.; Bestebroer, T. M.; Mulders, A.; Fouchier, R. A.; Herfst, S.
10.1101/2020.11.10.376053 — microbiology — Posted on 2020-11-10
2791 Evaluation of the antiviral effect of chlorine dioxide (ClO2) using a vertebrate model inoculated with avian coronavirus
Zambrano-Estrada, X.; Dominguez-Sanchez, C. A.; Banuet-Martinez, M.; Guerrero-de la Rosa, F.; Garcia-Gasca, T.; Prieto-Valiente, L.; Acevedo-Whitehouse, K.
10.1101/2020.10.13.336768 — microbiology — Posted on 2020-11-10
2792 CD127 imprints functional heterogeneity to diversify monocyte responses in human inflammatory diseases
Zhang, B.; Zhang, Y.; Xiong, L.; Li, Y.; Zhang, Y.; Zhao, J.; Jiang, H.; Li, C.; Liu, Y.; Liu, X.; Liu, H.; Ping, Y.-F.; Zhang, Q. C.; Zhang, Z.; Bian, X.-W.; Zhao, Y.; Hu, X.
10.1101/2020.11.10.376277 — immunology — Posted on 2020-11-10
2793 Integrative Transcriptomic Analysis Reveals the Immune Mechanism for A CyHV-3-Resistant Common Carp Strain
Jia, Z.; Wu, N.; Jiang, X.; Li, H.; Sun, J.; Shi, M.; Li, C.; Hu, X.; Ge, Y.; Ye, W.; Tang, Y.; Cheng, Y.; Xia, X.-Q.; Shi, L.
10.1101/2020.11.10.375915 — immunology — Posted on 2020-11-10
2794 Decoding subjective emotional arousal from EEG during an immersive Virtual Reality experience
Hofmann, S. M.; Klotzsche, F.; Mariola, A.; Nikulin, V. V.; Villringer, A.; Gaebler, M.
10.1101/2020.10.24.353722 — neuroscience — Posted on 2020-11-10
2798 A new microfluidic concept for successful in vitro culture of mouse embryos
Mancini, V.; McKeegan, P.; Rutledge, A. C.; Condreanu, S. G.; Sherrod, S. D.; McLean, J. A.; Picton, H. M.; Pensabene, V.
10.1101/2020.11.10.376160 — bioengineering — Posted on 2020-11-10
2799 A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples
Liu, T.; Chen, Z.; Chen, W.; Chen, X.; Hosseini Asanjan, M.; Yang, Z.; Li, J.; Ho, D.; Turay, D.; Gheorghe, C.; Jones, W.; Wang, C.
10.1101/2020.11.10.375022 — genomics — Posted on 2020-11-10
2800 Susceptibility of well-differentiated airway epithelial cell cultures from domestic and wildlife animals to SARS-CoV-2
Gultom, M.; Licheri, M.; Laloli, L.; Wider, M.; Straessle, M.; Steiner, S.; Kratzel, A.; Thao, T. T. N.; Stalder, H.; Portmann, J.; Holwerda, M.; V'kovski, P.; Ebert, N.; Stokar - Regenscheit, N.; Gurtner, C.; Zanolari, P.; Posthaus, H.; Schuller, S.; Moreira - Soto, A.; Vicente - Santos, A.; Corrales - Aguilar, E.; Ruggli, N.; Tekes, G.; von Messling, V.; Sawatsky, B.; Thiel, V.; Dijkman, R.
10.1101/2020.11.10.374587 — microbiology — Posted on 2020-11-10
2806 Inhibition of histone acetyltranserase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a novel gain of function.
Kumar, M.; Molkentine, D.; Molkentine, J.; Bridges, K.; Xie, T.; Yang, L.; Hefner, A.; Gao, M.; Frederick, M. J.; Seth, S.; Abdelhakiem, M.; Beadle, B.; Johnson, F. M.; Wang, J.; Shen, L.; Heffernan, T.; Sheth, A.; Ferris, R.; Myers, J. N.; Pickering, C. R.; Skinner, H. D.
10.1101/2020.04.10.028217 — cancer biology — Posted on 2020-11-10
2807 PHERI - Phage Host Exploration pipeline.
Balaz, A.; Kajsik, M.; Budis, J.; Szemes, T.; Turna, J.
10.1101/2020.05.13.093773 — bioinformatics — Posted on 2020-11-10
2811 3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system
Leung, C.; Robbins, S.; Moss, A.; Heal, M.; Osanlouy, M.; Christie, R.; Farahani, N.; Monteith, C.; Chen, J.; Hunter, P.; Tappan, S.; Vadigepalli, R.; Cheng, Z.; Schwaber, J. S.
10.1101/2020.07.29.227538 — neuroscience — Posted on 2020-11-10
2813 Cancer associated talin point mutations disorganise cell adhesion and migration
Azizi, L.; Cowell, A.; Mykuliak, V. V.; Goult, B. T.; Turkki, P.; Hytonen, V. P.
10.1101/2020.03.25.008193 — cancer biology — Posted on 2020-11-10
2814 Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone
Pal, M.; Munoz-Hernandez, H.; Bjorklund, D.; Zhou, L.; Degliesposti, G.; Skehel, J. M.; Hesketh, E. L.; Thompson, R. F.; Pearl, L. H.; Llorca, O.; Prodromou, C.
10.1101/2020.11.09.374355 — biochemistry — Posted on 2020-11-10
2816 Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis
Ryan, S. M.; Almassey, M.; Burch, A. M.; Ngo, G.; Martin, J. M.; Myers, D.; Compton, D.; Barbee, S.; Mortimer, N. T.; Sanyal, S.; Vrailas-Mortimer, A.
10.1101/552729 — genetics — Posted on 2020-11-10
2825 Identification and phenotype of MAIT cells in cattle and their response to bacterial infections
Edmans, M. D.; Connelley, T. K.; Jayaraman, S.; vrettou, C.; Vordermeier, M.; Mak, J. Y. W.; Liu, L.; Fairlie, D. P.; Maze, E. A.; Chrun, T.; Klenerman, P.; Eckle, S. B. G.; Tchilian, E.; Benedictus, L.
10.1101/2020.11.09.374678 — immunology — Posted on 2020-11-10
2830 Diverse chemotypes drive biased signaling by cannabinoid receptors
Miljus, T.; Heydenreich, F. M.; Gazzi, T.; Kimbara, A.; Rogers-Evans, M.; Nettekoven, M.; Zirwes, E.; Osterwald, A.; Rufer, A. C.; Ullmer, C.; Guba, W.; Le Gouill, C.; Fingerle, J.; Nazare, M.; Grether, U.; Bouvier, M.; Veprintsev, D. B.
10.1101/2020.11.09.375162 — pharmacology and toxicology — Posted on 2020-11-10
2840 PHAIR, A biosensor for pH measurement in air-liquid interface of human airway epithelial cells
Dabaghi, M.; Saraei, N.; Xu, G.; Chandiramohan, A.; Yeung, J.; Nguyen, J. P.; Vukmirovic, M.; Selvaganapathy, P. R.; Hirota, J. A.
10.1101/2020.11.09.375683 — bioengineering — Posted on 2020-11-10
2841 Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
Sheng, X.; Ma, Z.; Wu, J.; Liu, H.; Qiu, C.; Miao, Z.; Seasock, M. J.; Palmer, M.; Shin, M. K.; Duffin, K. L.; Pullen, S. S.; Edwards, T. L.; Hellwege, J. N.; Hung, A. M.; Li, M.; Voight, B.; Coffman, T.; Brown, C. D.; Susztak, K.
10.1101/2020.11.09.375592 — genetics — Posted on 2020-11-10
2844 Environmental vulnerability of the global ocean plankton community interactome
Chaffron, S.; Delage, E.; Budinich, M.; Vintache, D.; Henry, N.; Nef, C.; Ardyna, M.; Zayed, A. A.; Junger, P. C.; Galand, P. E.; Lovejoy, C.; Murray, A. E.; Sarmento, H.; Tara Oceans Coordinators, ; Acinas, S. G.; Babin, M.; Iudicone, D.; Jaillon, O.; Karsenti, E.; Wincker, P.; Karp-Boss, L.; Sullivan, M. B.; Bowler, C.; de Vargas, C.; Eveillard, D.
10.1101/2020.11.09.375295 — ecology — Posted on 2020-11-10
2847 Deconstructing the mouse olfactory percept through an olfactory ethological atlas
Manoel, D.; Makhlouf, M.; Arayata, C. J.; Sathappan, A.; Da'as, S.; Abdelrahman, D.; Selvaraj, S.; Hasnah, R.; Mainland, J. D.; Gerkin, R. C.; Saraiva, L. R.
10.1101/2020.11.09.374637 — neuroscience — Posted on 2020-11-10
2849 Novelty Processing Depends on Medial Temporal Lobe Structures
Schomaker, J.; Grouls, M. M. E.; Rau, E.; Hendriks, M.; Colon, A.; Meeter, M.
10.1101/2020.11.10.374538 — neuroscience — Posted on 2020-11-10
2851 AGORA2: Large scale reconstruction of the microbiome highlights wide-spread drug-metabolising capacities.
Heinken, A.; Acharya, G.; Ravcheev, D. A.; Hertel, J.; Nyga, M.; Okpala, O. E.; Hogan, M.; Magnusdottir, S.; Martinelli, F.; Preciat, G.; Edirisinghe, J. N.; Henry, C. S.; Fleming, R. M. T.; Thiele, I.
10.1101/2020.11.09.375451 — systems biology — Posted on 2020-11-10
2852 A plant lipocalin is required for retinal-mediated de novo root organogenesis
Dickinson, A. J.; Zhang, J.; Luciano, M.; Schnermann, M.; Dinneny, J. R.; Benfey, P. N.
10.1101/2020.11.09.375444 — plant biology — Posted on 2020-11-10
2853 EphB6 regulates TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells
MONTAGNER, M.; Zangrossi, M.; Chakravarty, P.; Romani, P.; Ratcliffe, C. D. H.; Hooper, S.; Dori, M.; Forcato, M.; Bicciato, S.; Dupont, S.; Sahai, E.
10.1101/2020.11.10.376186 — cancer biology — Posted on 2020-11-10
2854 Insights into G-Quadruplex-Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding
Stadlbauer, P.; Islam, B.; Otyepka, M.; Chen, J.; monchaud, d.; Zhou, J.; Mergny, J.-L.; Sponer, J.
10.1101/2020.11.09.375691 — biophysics — Posted on 2020-11-10
2855 Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super-relaxed state: multiscale measurements and computational modeling
Vander Roest, A. S.; Liu, C.; Morck, M. M.; Kooiker, K. B.; Jung, G.; Song, D.; Dawood, A.; Jhingran, A.; Pardon, G.; Ranjbarvaziri, S.; Fajardo, G.; Zhao, M.; Campbell, K. S.; Pruitt, B.; Spudich, J. A.; Ruppel, K. M.; Bernstein, D.
10.1101/2020.11.10.375493 — biophysics — Posted on 2020-11-10
2858 Combined assessment of MHC binding and antigen expression improves T cell epitope predictions
Kosaloglu-Yalcin, Z.; Lee, J.; Nielsen, M.; Greenbaum, J.; Schoenberger, S. P.; Miller, A.; Kim, Y. J.; Sette, A.; Peters, B.
10.1101/2020.11.09.375204 — bioinformatics — Posted on 2020-11-10
2864 Evolution of Natural Lifespan Variation and Molecular Strategies of Extended Lifespan
Kaya, A.; PHUA, C.-Z.-J.; Lee, M.; Wang, L.; Tyshkovskiy, A.; Ma, S.; Liu, W.; Harrison, B.; Zhao, X.; Zhou, X.; Wasko, B. M.; Bammler, T. K.; Promislow, D. E. L.; Kaeberlein, M.; Gladyshev, V. N.
10.1101/2020.11.09.374488 — genetics — Posted on 2020-11-10
2866 Preventing extinctions post-2020 requires recovery actions and transformative change
Bolam, F. C.; Ahumada, J.; Akcakaya, H. R.; Brooks, T. M.; Elliott, W.; Hoban, S.; Mair, L.; Mallon, D.; McGowan, P. J. K.; Raimondo, D.; Rodriguez, J. P.; Roe, D.; Seddon, M. B.; Shen, X.; Stuart, S. N.; Watson, J. E. M.; Butchart, S. H. M.
10.1101/2020.11.09.374314 — ecology — Posted on 2020-11-10
2867 Subsidy Accessibility Drives Asymmetric Food Web Responses
Gutgesell, M. K.; McMeans, B. C.; Guzzo, M. M.; deGroot, V.; Fisk, A. T.; Johnson, T. B.; McCann, K.
10.1101/2020.11.09.374629 — ecology — Posted on 2020-11-10
2869 PCMD-1 bridges the centrioles and the PCM scaffold in C. elegans
Stenzel, L.; Mehler, J.; Schreiner, A.; Uestuener, S.; Zuccoli, E.; Zanin, E.; Mikeladze-Dvali, T.
10.1101/2020.11.09.375865 — cell biology — Posted on 2020-11-10
2871 Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus
Baker, S. F.; Meistermann, H.; Tzouros, M.; Baker, A.; Golling, S.; Polster, J. S.; Ledwith, M. P.; Gitter, A.; Augustin, A.; Javanbakht, H.; Mehle, A.
10.1101/2020.11.09.355982 — microbiology — Posted on 2020-11-10
2872 Contagious Antibiotic Resistance: Plasmid Transfer Among Bacterial Residents of the Zebrafish Gut
Loftie-Eaton, W.; Crabtree, A.; Perry, D.; Millstein, J.; Robison, B. D.; Forney, L. J.; Top, E. M.
10.1101/2020.11.09.375964 — microbiology — Posted on 2020-11-10
2875 IL-7-adjuvanted vaginal vaccine elicits strong mucosal immune responses in non-human primates
Logerot, S.; Figueiredo, S.; Charmeteau, B.; Sandouk, A.; Drillet-Dangeard, A.-S.; Bomsel, M.; Bourgault-Villada, I.; Couedel-Courteille, A.; Cheynier, R.; Rancez, M.
10.1101/2020.11.09.374405 — immunology — Posted on 2020-11-10
2876 Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
Raghunandan, A.; Ladron-de-Guevara, A.; Tithof, J.; Mestre, H.; Nedergaard, M.; Thomas, J. H.; Kelley, D. H.
10.1101/2020.11.09.374512 — neuroscience — Posted on 2020-11-10
2880 A Simple and Efficient Pipeline for Construction, Merging, Expansion, and Simulation of Large-Scale, Single-Cell Mechanistic Models
Erdem, C.; Bensman, E. M.; Mutsuddy, A.; Saint-Antoine, M. M.; Bouhaddou, M.; Blake, R. C.; Dodd, W.; Gross, S. M.; Heiser, L. M.; Feltus, F. A.; Birtwistle, M. R.
10.1101/2020.11.09.373407 — systems biology — Posted on 2020-11-10
2882 Full species-wide leaf and seed ionomic diversity of Arabidopsis thaliana
Campos, A. C. A. L.; van Dijk, W. F. A.; Ramakrishna, P.; Giles, T.; Korte, P.; Douglas, A.; Smith, P.; Salt, D. E.
10.1101/2020.11.09.373282 — plant biology — Posted on 2020-11-10
2887 Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes
Yermanos, A.; Agrafiotis, A.; Yates, J.; Papadopoulou, C.; Robbiani, D.; Bieberich, F.; Vazquez-Lombardi, R.; Neumeier, D.; Oxenius, A.; Reddy, S. T.
10.1101/2020.11.09.374280 — immunology — Posted on 2020-11-10
2888 Human antigen-specific memory natural killer cell responses develop against HIV-1 and influenza virus and are dependent on MHC-E restriction
Jost, S.; Lucar, O.; Yoder, T.; Kroll, K.; Sugawara, S.; Smith, S.; Jones, R.; Tweet, G.; Werner, A.; Tomezsko, P. J.; Dugan, H. L.; Ghofrani, J.; Altfeld, M.; Grundhoff, A.; Muller-Trutwin, M.; Goepfert, P.; Reeves, R. K.
10.1101/2020.11.09.374348 — immunology — Posted on 2020-11-10
2891 Novel proteostasis reporter mouse reveals different effects of cytoplasmic and nuclear aggregates on protein quality control in neurons
Blumenstock, S.; Schulz-Trieglaff, E. K.; Bolender, A.-L.; Voelkl, K.; Lapios, P.; Lindner, J.; Hipp, M. S.; Hartl, U.; Klein, R.; Dudanova, I.
10.1101/2020.11.09.374231 — neuroscience — Posted on 2020-11-10
2899 Point Technology Illuminates The Processing Of Polymerase-Associated Intact Nascent Transcripts
Sousa-Luis, R.; Dujardin, G.; Zukher, I.; Kimura, H.; Carmo-Fonseca, M.; Proudfoot, N.; Nojima, T.
10.1101/2020.11.09.374108 — genomics — Posted on 2020-11-10
2901 Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression
Zhang, L.; Padilla-Flores, T.; Hernandez, V. S.; Campos-Lira, E.; Zetter, M. A.; Escobar, L. I.; Eiden, L. E.
10.1101/2020.11.07.373027 — neuroscience — Posted on 2020-11-10
2903 NASA GeneLab RNA-Seq Consensus Pipeline: Standardized Processing of Short-Read RNA-Seq Data
Overbey, E. G.; Saravia-Butler, A. M.; Zhang, Z.; Rathi, K. S.; Fogle, H.; da Silveira, W. A.; Barker, R. J.; Bass, J. J.; Beheshti, A.; Berrios, D. C.; Blaber, E. A.; Cekanaviciute, E.; Costa, H. A.; Davin, L. B.; Fisch, K. M.; Gebre, S. G.; Geniza, M.; Gilbert, R.; Gilroy, S.; Hardiman, G.; Herranz, R.; Kidane, Y. H.; Kruse, C. P. S.; Lee, M. D.; Liefeld, T.; Lewis, N. G.; McDonald, J. T.; Meller, R.; Mishra, T.; Perera, I.; Ray, S.; Reinsch, S.; Rosenthal, S. B.; Strong, M.; Szewczyk, N. J.; Tahimic, C. G. T.; Taylor, D. M.; Vandenbrink, J. P.; Villacampa, A.; Weging, S.; Wolverton, C.; Wya
10.1101/2020.11.06.371724 — bioinformatics — Posted on 2020-11-10
2904 Machine learning reveals sequence-function relationships in family 7 glycoside hydrolases
Gado, J.; Harrison, B. E.; Sandgren, M.; Stahlberg, J.; Beckham, G. T.; Payne, C. M.
10.1101/2020.11.06.372003 — bioinformatics — Posted on 2020-11-10
2905 Genome-scale metabolic reconstruction analysis of Clostridioides difficile identifies conserved patterns of virulence-related metabolic reprogramming
Jenior, M. L.; Leslie, J. L.; Powers, D. A.; Garrett, E. M.; Walker, K. A.; Dickenson, M. E.; Petri, W. A.; Tamayo, R.; Papin, J. A.
10.1101/2020.11.09.373480 — bioengineering — Posted on 2020-11-10
2906 The role of XPB/Ssl2 double-stranded DNA translocase processivity in transcription start-site scanning.
Tomko, E. J.; Luyties, O.; Rimel, J. K.; Tsai, C.-L.; Fuss, J. O.; Fishburn, J.; Hahn, S.; Tsutakawa, S. E.; Taatjes, D. J.; Galburt, E. A.
10.1101/2020.11.09.375329 — biochemistry — Posted on 2020-11-10
2907 Evolution of the complex transcription network controlling biofilm formation in Candida species
Mancera, E.; Nocedal, I.; Hammel, S.; Gulati, M.; Mitchell, K. F.; Andes, D. R.; Nobile, C. J.; Butler, G.; Johnson, A. D.
10.1101/2020.11.08.373514 — evolutionary biology — Posted on 2020-11-10
2912 Microbiota-mediated competition between pest insects and its application to the evolution-proof protection of crops
rombaut, a.; Gallet, R.; Qitout, K.; Samy, M.; Guilhot, R.; Ghirardini, P.; Becher, P. G.; Xuereb, A.; Gibert, P.; Fellous, S.
10.1101/2020.08.05.238055 — evolutionary biology — Posted on 2020-11-10
2915 B-1 lymphoid cells develop independently of Notch signaling during mouse embryonic development.
Azevedo, N.; Bertesago, E.; Ismailoglu, I.; Kyba, M.; Kobayashi, M.; Ditadi, A.; Yoshimoto, M.
10.1101/2020.11.09.375634 — developmental biology — Posted on 2020-11-09
2916 Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids
Valle-Encinas, E.; Aleksieva, N.; Velasco Martinez, C.; Dawes, M.; Zverev, M.; Muller, M.; Offergeld, A.; Smalley, M. J.; Hogan, C.; Forbes, S. J.; Bird, T. G.; Dale, T. C.
10.1101/2020.11.09.374462 — cell biology — Posted on 2020-11-09
2918 An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish
Lumaquin, D.; Johns, E.; Weiss, J.; Montal, E.; Ooladipupo, O.; Abuhashem, A.; White, R.
10.1101/2020.11.09.375667 — cell biology — Posted on 2020-11-09
2920 Influence of tropical pastures on grazing behavior parameters of young lambs
Tontini, J. F.; Poli, C. H. E. C.; Hampel, V. d. S.; Farias, M. d. S.; Fajardo, N. M.; Silva, J. A. d.; Farinatti, L. H. E.; Muir, J. P.; Jalise Fabiola Tontini, Cesar Henrique Espirito Candal Poli, Viviane da Silva Hampel,,
10.1101/2020.11.09.374025 — animal behavior and cognition — Posted on 2020-11-09
2921 Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals
Hivert, V.; Sidorenko, J.; Rohart, F.; Goddard, M. E.; Yang, J.; Wray, N. R.; Yengo, L.; Visscher, P. M.
10.1101/2020.11.09.375501 — genetics — Posted on 2020-11-09
2925 Evaluation of the Abbott ARCHITECT HIV Ag/Ab Combo Assay for Determining Recent HIV-1 Infection
Curtis, K. A.; Rudolph, D. L.; Yi, P.; Delaney, K.; Anastos, K.; DeHovitz, J.; Kassaye, S.; Hanson, C.; French, A.; Golub, E.; Adimora, A.; Ofotokun, I.; Bolivar, H.; Kempf, M.-C.; Peters, P. J.; Switzer, W. M.
10.1101/2020.11.09.374017 — microbiology — Posted on 2020-11-09
2928 Oligodendrocyte secreted factors shape hippocampal GABAergic neuron transcriptome and physiology
Mazuir, E.; Richevaux, L.; Nassar, M.; Robil, N.; de la Grange, P.; Lubetzki, C.; Fricker, D.; Sol-Foulon, N.
10.1101/2020.11.09.374306 — neuroscience — Posted on 2020-11-09
2929 Theta rhythmicity governs the timing of behavioral and hippocampal responses in humans specifically during memory-dependent tasks
ter Wal, M.; Linde Domingo, J.; Lifanov, J.; Roux, F.; Kolibius, L.; Gollwitzer, S.; Lang, J.; Hamer, H.; Rollings, D.; Sawlani, V.; Chelvarajah, R.; Staresina, B.; Hanslmayr, S.; Wimber, M.
10.1101/2020.11.09.374264 — neuroscience — Posted on 2020-11-09
2933 Characterization of the Cannabis sativa glandular trichome proteome
Conneely, L. J.; Mauleon, R.; Mieog, J.; Barkla, B. J.; Kretzschmar, T.
10.1101/2020.11.09.373910 — plant biology — Posted on 2020-11-09
2944 Extending the integrate-and-fire model to account for metabolic dependencies
Jaras, I.; Harada, T.; Orchard, M. E.; Maldonado, P. E.; Vergara, R. C.
10.1101/2020.11.04.367102 — neuroscience — Posted on 2020-11-09
2945 Therapy-induced senescence in normal tissue promotes breast cancer metastasis
Perkins, D. W.; Haider, S.; Roberston, D.; Buus, R.; O'Leary, L.; Isacke, C. M.
10.1101/2020.10.17.343590 — cancer biology — Posted on 2020-11-09
2947 CytoPy: an autonomous cytometry analysis framework
Burton, R. J.; Ahmed, R.; Cuff, S.; Artemiou, A.; Eberl, M.
10.1101/2020.04.08.031898 — bioinformatics — Posted on 2020-11-09
2953 Evidence of genetic overlap between circadian preference and brain white matter microstructure
Garcia-Marin, L. M.; Alcauter, S.; Campos, A. I.; Mulcahy, A.; Kho, P.-F.; Cuellar-Partida, G.; Renteria, M. E.
10.1101/2020.11.09.374199 — neuroscience — Posted on 2020-11-09
2954 RADA is a main branch migration factor in plant mitochondrial recombination and its defect leads to mtDNA instability and cell cycle arrest
Chevigny, N.; Weber-Lotfi, F.; Nadiras, C.; Fertet, A.; Le Ret, M.; Bichara, M.; Erhardt, M.; Dietrich, A.; Raynaud, C.; Gualberto, J. M.
10.1101/856716 — plant biology — Posted on 2020-11-09
2955 Phylogenetic reconstruction of myeloproliferative neoplasm reveals very early origins and lifelong evolution
Williams, N.; Lee, J.; Moore, L.; Baxter, E. J.; Hewinson, J.; Dawson, K. J.; Menzies, A.; Godfrey, A. L.; Green, A. R.; Campbell, P. J.; Nangalia, J.
10.1101/2020.11.09.374710 — cancer biology — Posted on 2020-11-09
2961 SlicerMorph: An open and extensible platform to retrieve, visualize and analyze 3D morphology
Rolfe, S.; Pieper, S.; Porto, A.; Diamond, K.; Winchester, J.; Shan, S.; Kirveslahti, H.; Boyer, D.; Summer, A.; Maga, A. M.
10.1101/2020.11.09.374926 — evolutionary biology — Posted on 2020-11-09
2968 Cloning, Expression and Biophysical Characterization of a Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain COVID-19 Vaccine Candidate
Chen, W.-H.; Wei, J.; Kundu, R. T.; Adhikari, R.; Liu, Z.; Lee, J.; Versteeg, L.; Poveda, C.; Keegan, B.; Villar, M. J.; de Araujo Leao, A. C.; Altieri Rivera, J.; Gillespie, P. M.; Pollet, J.; Strych, U.; Zhan, B.; Hotez, P. J.; Bottazzi, M. E.
10.1101/2020.11.09.373449 — immunology — Posted on 2020-11-09
2969 Neutrophil extracellular traps induce the epithelial-mesenchymal transition: implications in post-COVID-19 fibrosis
Pandolfi, L.; Bozzini, S.; Vanessa, F.; Percivalle, E.; De Luigi, A.; Violatto, M. B.; Lopez, G.; Gabanti, E.; Carsana, L.; D'Amato, M.; Morosini, M.; De Amici, M.; Nebuloni, M.; Fossali, T.; Colombo, R.; Saracino, L.; Codullo, V.; Gnecchi, M.; Bigini, P.; Baldanti, F.; Lilleri, D.; Meloni, F.
10.1101/2020.11.09.374769 — immunology — Posted on 2020-11-09
2972 Decoding subjective emotional arousal from EEG during an immersive Virtual Reality experience
Hofmann, S. M.; Klotzsche, F.; Mariola, A.; Nikulin, V. V.; Villringer, A.; Gaebler, M.
10.1101/2020.10.24.353722 — neuroscience — Posted on 2020-11-09
2975 Increased and ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains in hexaploid wheat in a dosage-dependent manner
Adamski, N. M.; Simmonds, J.; Brinton, J. F.; Backhaus, A. E.; Chen, Y.; Smedley, M.; Hayta, S.; Florio, T.; Crane, P.; Scott, P.; Pieri, A.; Hall, O.; Barclay, E. J.; Clayton, M.; Doonan, J. H.; Nibau, C.; Uauy, C.
10.1101/2020.11.09.375154 — plant biology — Posted on 2020-11-09
2976 TRPM2 promotes pancreatic cancer by PKC/MAPK pathway
Lin, R.; Bao, X.; Wang, H.; Zhu, S.; Liu, Z.; Chen, Q.; Ai, K.; Shi, B.
10.1101/2020.11.09.373035 — cancer biology — Posted on 2020-11-09
2977 Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy
Navikas, V.; Leitao, S. M.; Grussmayer, K. S.; Descloux, A.; Drake, B.; Yserentant, K.; Werther, P.; Herten, D.-P.; Wombacher, R.; Radenovic, A.; Fantner, G. E.
10.1101/2020.11.09.374157 — biophysics — Posted on 2020-11-09
2978 3D nanoscale analysis of bone healing around degrading Mg implants studied by X-ray scattering tensor tomography
Liebi, M.; Lutz-Bueno, V.; Guizar-Sicairos, M.; Schoenbauer, B. M.; Eichler, J.; Martinelli, E.; Loeffler, J. F.; Weinberg, A.; Lichtenegger, H.; Gruenewald, T. A.
10.1101/2020.11.09.375253 — biophysics — Posted on 2020-11-09
2980 Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone
Pearl, L. H.; Pal, M.; Munoz-Hernandez, H.; Bjorklund, D.; Zhou, L.; Degliesposti, G.; Skehel, J. M.; Hesketh, E. L.; Thompson, R. F.; Llorca, O.; Prodromou, C.
10.1101/2020.11.09.374355 — biochemistry — Posted on 2020-11-09
2983 Dilp8 controls a time window for tissue size adjustment in Drosophila
Boulan, L.; Blanco-Obregon, D.; El Marzkioui, K.; Brutscher, F.; Andersen, D. S.; Colombani, J.; Narasimha, S.; Leopold, P.
10.1101/2020.11.09.375063 — developmental biology — Posted on 2020-11-09
2984 Importin α7 deficiency causes infertility in male mice by disrupting spermatogenesis
Liu, N.; Qadri, F.; Busch, H.; Huegel, S.; Sihn, G.; Chuykin, I.; Hartmann, E.; Bader, M.; Rother, F.
10.1101/2020.11.09.374652 — developmental biology — Posted on 2020-11-09
2986 Essential role of non-vesicular lipid transport in microtubule-controlled cell polarisation
Hersberger-Trost, M.; Dreher, D.; Huisman, S. M.; Kijowski, A. R.; Gemuenden, M.; Klemm, R. W.; Brunner, D.
10.1101/2020.11.09.374702 — cell biology — Posted on 2020-11-09
2988 Virucidal efficacy of different formulations for hand and surface disinfection targeting SARS CoV-2
Steinhauer, K.; Meister, T. L.; Todt, D.; Krawczyk, A.; Passvogel, L.; Becker, B.; Paulmann, D.; Bischoff, B.; Eggers, M.; Pfaender, S.; Brill, F.; Steinmann, E.
10.1101/2020.11.08.373738 — microbiology — Posted on 2020-11-09
2989 Gain-of-function assay for SARS-CoV-2 Mpro inhibition in living cells
Moghadasi, S. A.; Becker, J. T.; Belica, C.; Wick, C.; Brown, W. L.; Harris, R.
10.1101/2020.11.09.375139 — microbiology — Posted on 2020-11-09
2990 Small Animal Jet Injection Technique Results in Enhanced Immunogenicity of Hantavirus DNA Vaccines
Brocato, R.; Kwilas, S. A.; Josleyn, M. D.; Long, S.; Zeng, X.; Perley, C. C.; Principe, L. M.; Somerville, B. C.; Cohen, M. V.; Hooper, J.
10.1101/2020.11.09.374439 — microbiology — Posted on 2020-11-09
2992 Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome
Porritt, R. A.; Paschold, L.; Noval Rivas, M.; Cheng, M. H.; Yonker, L. M.; Chandnani, H.; Lopez, M.; Simnica, D.; Schultheiss, C.; Santiskulvong, C.; Van Eyk, J.; Fasano, A.; Bahar, I.; Binder, M.; Arditi, M.
10.1101/2020.11.09.372169 — immunology — Posted on 2020-11-09
2993 Potentiation of Long-Acting β2-Agonist and Glucocorticoid Responses in Human Airway Epithelial Cells by Modulation of Intracellular cAMP
Kim, Y.; Hou, V.; Huff, R. D.; Aguiar, J. A.; Revill, S.; Tiessen, N.; Cao, C.; Miller, M. S.; Inman, M. D.; Ask, K.; Doxey, A. C.; Hirota, J. A.
10.1101/2020.11.09.375089 — immunology — Posted on 2020-11-09
2994 Development of Targetable Multi-Drug Nanoparticles for Glioblastoma Treatment and In Vitro Evaluation in Glioblastoma Stem Cells
Smiley, S. B.; Yun, Y.; Ayyagari, P.; Shannon, H. E.; Pollok, K. E.; Vannier, M. W.; Das, S. K.; Veronesi, M. C.
10.1101/2020.11.08.373696 — cell biology — Posted on 2020-11-09
2995 Worrying drives cell migration in mechanically unrestrained environments
Welf, E. S.; Driscoll, M. K.; Sapoznik, E.; Murali, V. S.; Weems, A. D.; Roh-Johnson, M.; Dean, K. M.; Fiolka, R. P.; Danuser, G.
10.1101/2020.11.09.372912 — cell biology — Posted on 2020-11-09
2996 The self-peptide repertoire plays a critical role in transplant tolerance induction
Son, E. T.; Faridi, P.; Paul-Heng, M.; Leong, M.; English, K.; Ramarathinam, S. H.; Braun, A.; Dudek, N.; Alexander, I. E.; Lisowski, L.; Bertolino, P.; Bowen, D.; Purcell, A. W.; Mifsud, N.; Sharland, A. F.
10.1101/2020.11.09.359968 — immunology — Posted on 2020-11-09
2998 Spatiotemporal model of cellular mechanotransduction via Rho and YAP
Novev, J. K.; Heltberg, M. L.; Jensen, M. H.; Doostmohammadi, A.
10.1101/2020.11.09.372730 — biophysics — Posted on 2020-11-09
3006 Collagen induced inflammations
Ningchao, D.; Li, Y.; Xu, M.; Wu, C.; Chen, X.; Yang, F.; He, Q.; Liao, M.; Qiu, J.; Wang, C.; Sun, J.; Ma, X.; Sheng, G.; Du, K.; Nandakumar, K. S.; Song, L.
10.1101/2020.11.09.373761 — immunology — Posted on 2020-11-09
3009 Diverse and complex muscle spindle afferent firing properties emerge from multiscale muscle mechanics
Blum, K. P.; Campbell, K. S.; Horslen, B. C.; Nardelli, P.; Housley, S. N.; Cope, T. C.; Ting, L. H.
10.1101/858209 — neuroscience — Posted on 2020-11-09
3015 Adaptive current-flow models of ECT: Explaining individual static impedance, dynamic impedance, and brain current delivery
Unal, G.; Swami, J. K.; Canela, C.; Cohen, S.; Khadka, N.; Rad, M.; Short, B.; Argyelan, M.; Sackeim, H.; Bikson, M.
10.1101/2020.11.08.373712 — bioengineering — Posted on 2020-11-09
3016 Brd4-bound enhancers drive cell intrinsic sex differences in glioblastoma
Kfoury, N.; Qi, Z.; Prager, B. C.; Wilkinson, M.; Broestl, L.; Berrett, K.; Moudgil, A.; Sankararaman, S.; Chen, X.; Gertz, J.; Rich, J. N.; Mitra, R.; Rubin, J. B.
10.1101/199059 — genomics — Posted on 2020-11-09
3020 Maintenance of adaptive dynamics and no detectable load in a range-edge out-crossing plant population
Takou, M.; Hämälä, T.; Koch, E.; Steige, K. A.; Dittberner, H.; Yant, L.; Genete, M.; Sunyaev, S.; Castric, V.; Vekemans, X.; Savolainen, O.; de Meaux, J.
10.1101/709873 — evolutionary biology — Posted on 2020-11-09
3022 A commercial antibody to the human condensin II subunit NCAPH2 cross-reacts with a SWI/SNF complex component
Cutts, E. E.; Taylor, G. C.; Pardo, M.; Yu, L.; Wills, J.; Choudhary, J. S.; Vannini, A.; Wood, A. J.
10.1101/2020.11.07.372599 — cell biology — Posted on 2020-11-09
3023 Nafamostat Mesylate in lipid carrier for nasal SARS-CoV2 titer reduction in a hamster model
Cornelissen, L.; Hoefsmit, E.; Rao, D.; Lijnsvelt, J.; ven Keulen, L.; van Es, M.; Grimm, V.; Medema, R. H.; Blank, C. U.
10.1101/2020.11.09.372375 — microbiology — Posted on 2020-11-09
3024 Human coronaviruses disassemble processing bodies
Robinson, C.-A.; Kleer, M.; Mulloy, R. P.; Castle, E. L.; Boudreau, B. Q.; Corcoran, J. A.
10.1101/2020.11.08.372995 — microbiology — Posted on 2020-11-09
3028 Resistance of endothelial cells to SARS-CoV-2 infection in vitro
Ahmetaj-Shala, B.; Peacock, T. P.; Baillon, L.; Swann, O.; Gashaw, H.; Barclay, W. S.; Mitchell, J. A.
10.1101/2020.11.08.372581 — immunology — Posted on 2020-11-09
3029 Olfactory neuron turnover in adult Drosophila
Fernandez-Hernandez, I.; Hu, E.; Bonaguidi, M. A.
10.1101/2020.11.08.371096 — neuroscience — Posted on 2020-11-09
3030 A Deep Graph Neural Network Architecture for Modelling Spatio-temporal Dynamics in resting-stating functional MRI Data
Azevedo, T.; Campbell, A.; Romero-Garcia, R.; Passamonti, L.; Bethlehem, R. A. I.; Lio, P.; Toschi, N.
10.1101/2020.11.08.370288 — neuroscience — Posted on 2020-11-09
3033 Drought shifts sorghum root metabolite and microbiome profiles and enriches the stress response factor pipecolic acid
Caddell, D. F.; Louie, K.; Bowen, B.; Sievert, J. A.; Hollingsworth, J.; Dahlberg, J.; Purdom, E. F.; Northen, T.; Coleman-Derr, D.
10.1101/2020.11.08.373399 — plant biology — Posted on 2020-11-09
3037 SARS-CoV-2 epitope mapping on microarrays highlights strong immune-response to N protein region
Musico, A.; Frigerio, R.; Mussida, A.; Barzon, L.; Sinigaglia, A.; Riccetti, S.; Gobbi, F.; Piubelli, C.; Bergamaschi, G.; Chiari, M.; Gori, A.; Cretich, M.
10.1101/2020.11.09.374082 — biochemistry — Posted on 2020-11-09
3039 Nodosome inhibition as a novel broad-spectrum antiviral strategy against arboviruses and SARS-CoV-2
Limonta, D.; Dyna-Dagman, L.; Branton, W.; Makio, T.; Wozniak, R. W.; Power, C.; Hobman, T. C.
10.1101/2020.11.05.370767 — microbiology — Posted on 2020-11-09
3041 Alternate primers for whole-genome SARS-CoV-2 sequencing
Cotten, M.; Bugembe, D. L.; Kaleebu, P.; Phan, M. V. T.
10.1101/2020.10.12.335513 — genomics — Posted on 2020-11-09
3042 Mice with Induced Pulmonary Comorbidities Display Severe Lung Inflammation and Mortality following Exposure to SARS-CoV-2
Falach, R.; Bar-On, L.; Lazar, S.; Kadar, T.; Mazor, O.; Aftalion, M.; Gur, D.; Shifman, O.; Israeli, O.; Cohen-Gihon, I.; Zaide, G.; Gutman, H.; Evgy, Y.; Vagima, Y.; Makdasi, E.; Stein, D.; Rosenfeld, R.; Alcalay, R.; Zahavy, E.; Levy, H.; Glinert, I.; Ben-Shmuel, A.; Israely, T.; Melamed, S.; Politi, B.; Achdout, H.; Yitzhaky, S.; Kronman, C.; Sabo, T.
10.1101/2020.10.28.358614 — pathology — Posted on 2020-11-09
3045 Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24
Cao, X.; Khitun, A.; Luo, Y.; Na, Z.; Phoodokmai, T.; Sappakhaw, K.; Olatunji, E.; Uttamapinant, C.; Slavoff, S. A.
10.1101/2020.03.04.977314 — genomics — Posted on 2020-11-09
3047 Global critical natural assets
Chaplin-Kramer, R.; Neugarten, R.; Sharp, R. P.; Collins, P. M.; Polasky, S.; Hole, D.; Schuster, R.; Strimas-Mackey, M.; Mulligan, M.; Brandon, C.; Diaz, S.; Fluet-Chouinard, E.; Gorenflo, L.; Johnson, J. A.; Keys, P. W.; Longley-Wood, K.; McIntyre, P. B.; Noon, M.; Pascual, U.; Reidy Liermann, C.; Roehrdanz, P.; Schmidt-Traub, G.; Shaw, M. R.; Spalding, M.; Turner, W. R.; van Soesbergen, A.; Watson, R.
10.1101/2020.11.08.361014 — ecology — Posted on 2020-11-09
3050 Exosomal melanotransferrin as a potential biomarker for metastatic melanoma
Bonhoure, A.; Henry, L.; Morille, M.; Assaoui, N.; Bellot, G.; Stoebner, P.-E.; Vidal, M.
10.1101/2020.11.09.373852 — cell biology — Posted on 2020-11-09
3053 Decreased homotopic interhemispheric functional connectivity in children with autism spectrum disorder
Yao, S.; Zhou, M.; Zhang, Y.; Zhang, Q.; Zhao, Z.; Jiang, X.; Xu, X.; Becker, B.; Kendrick, K. M.
10.1101/2020.11.08.373126 — neuroscience — Posted on 2020-11-09
3056 Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools
Bues, J.; Biocanin, M.; Pezoldt, J.; Dainese, R.; Chrisnandy, A.; Rezakhani, S.; Saelens, W.; Gardeux, V.; Gupta, R.; Russeil, J.; Saeys, Y.; Amstad, E.; Claassen, M.; Lutolf, M.; Deplancke, B.
10.1101/2020.05.19.103812 — bioengineering — Posted on 2020-11-09
3057 Genome information processing by the INO80 chromatin remodeler positions nucleosomes
Oberbeckmann, E.; Krietenstein, N.; Niebauer, V.; Wang, Y.; Schall, K.; Moldt, M.; Straub, T.; Rohs, R.; Hopfner, K.-P.; Korber, P.; Eustermann, S.
10.1101/2020.11.03.366690 — biochemistry — Posted on 2020-11-09
3058 Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis
Ryan, S. M.; Almassey, M.; Burch, A. M.; Ngo, G.; Martin, J. M.; Myers, D.; Compton, D.; Barbee, S.; Mortimer, N. T.; Sanyal, S.; Vrailas-Mortimer, A.
10.1101/552729 — genetics — Posted on 2020-11-09
3059 Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression
Gao, P.; Lyu, Q.; Ghanam, A. R.; Lazzarotto, C. R.; Newby, G. A.; Zhang, W.; Choi, M.; Slivano, O. J.; Holden, K.; Walker, J. A.; Kadina, A. P.; Munroe, R. J.; Abratte, C. M.; Schimenti, J. C.; Liu, D. R.; Tsai, S. Q.; Long, X.; Miano, J. M.
10.1101/2020.11.07.372748 — genetics — Posted on 2020-11-09
3066 Interplay between Desmoglein2 and hypoxia controls metastasis in breast cancer
Chang, P.-H.; Chen, M.-C.; Tsai, Y.-P.; Tan, G. Y. T.; Hsu, P.-H.; Jeng, Y.-M.; Tsai, Y.-F.; Yang, M.-H.; Hwang-Verslues, W. W.
10.1101/790519 — cancer biology — Posted on 2020-11-09
3069 Sex determination through X-Y heterogamety in Salix nigra
Sanderson, B. J.; Feng, G.; Hu, N.; Carlson, C. H.; Smart, L. B.; Keefover-Ring, K.; Yin, T.; Ma, T.; Liu, J.; DiFazio, S.; Olson, M. S.
10.1101/2020.03.23.000919 — genomics — Posted on 2020-11-09
3078 Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression
Gao, P.; Lyu, Q.; Ghanam, A. R.; Lazzarotto, C. R.; Newby, G. A.; Zhang, W.; Choi, M.; Slivano, O. J.; Holden, K.; Walker, J. A.; Kadina, A. P.; Munroe, R. J.; Abratte, C. M.; Schimenti, J. C.; Liu, D. R.; Tsai, S. Q.; Miano, J. M.
10.1101/2020.11.07.372748 — genetics — Posted on 2020-11-08
3079 Leveraging the Mendelian Disorders of the Epigenetic Machinery to Systematically Map Functional Epigenetic Variation
Luperchio, T. R.; Boukas, L.; Zhang, L.; Pilarowski, G. O.; Jiang, J.; Kalinousky, A.; Hansen, K. D.; Bjornsson, H. T.
10.1101/2020.11.08.373456 — genetics — Posted on 2020-11-08
3084 Cell-free DNA (cfDNA) and exosome profiling from a year-long humanspaceflight reveals circulating biomarkers
Bezdan, D.; Grigorev, K.; Meydan, C.; Pelissier Vatter, F.; Ciofi, M.; Rao, V.; Nakahira, K.; Burnham, P.; Afshinnekoo, E.; Westover, C.; Butler, D.; Moszary, C.; MacKay, M.; Foox, J.; Mishra, T.; Lucotti, S.; Brinda, R.; Melnick, A.; Zhang, H.; Matei, I.; Kelsen, D.; Yu, K.; Lyden, D.; Lynn, T.; Bailey, S.; Snyder, M.; Garrett-Bakelman, F.; Ossowski, S.; De Vlaminck, I.; Mason, C.
10.1101/2020.11.08.373530 — cell biology — Posted on 2020-11-08
3085 Mitochondrial profiling reveals dynamic, sex- and age-specific mitochondrial phenotypes in human immune cell subtypes
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2020-11-08
3088 in vitro: Natural Compounds (Thymol, Carvacrol, Hesperidine, And Thymoquinone) Against SARS-CoV2 Strain Isolated From Egyptian Patients
Seadawy, M. G.; Gad, A. F.; Harty, B. E.; Mohamed, M. F.; ELdesoky, M. S.; Elfiky, A. A.; Ahmed, A.; Zekri, A. N.
10.1101/2020.11.07.367649 — microbiology — Posted on 2020-11-08
3091 Invariant Odor Recognition with ON-OFF Neural Ensembles
Nizampatnam, S.; Zhang, L.; Chandak, R.; Katta, N.; Raman, B.
10.1101/2020.11.07.372870 — neuroscience — Posted on 2020-11-08
3092 Longitudinal Auditory Pathophysiology Following Mild Blast Induced Trauma
Han, E. X.; Fernandez, J. M.; Swangberg, C.; Shi, R.; Bartlett, E. L.
10.1101/2020.11.06.371591 — neuroscience — Posted on 2020-11-08
3096 The diagonal band of broca continually regulates olfactory-mediated behaviors by modulating odor-evoked responses within the olfactory bulb
Schwarz, I.; Mueller, M.; Pavlova, I.; Schweihoff, J. F.; Musacchio, F.; Mittag, M.; Fuhrmann, M.; Schwarz, M. K.
10.1101/2020.11.07.372649 — neuroscience — Posted on 2020-11-08
3100 Whole genome sequencing provides evidence of two biologically and clinically distinct entities of asymptomatic monoclonal gammopathies: progressive versus stable myeloma precursor condition
Oben, B.; Froyen, G.; Maclachlan, K. H.; Leongamornlert, D.; Abascal, F.; Zheng-Lin, B.; Yellapantula, V.; Derkach, A.; Geerdens, E.; Diamond, B. T.; Arijs, I.; Maes, B.; Vanhees, K.; Hultcrantz, M.; Manasanch, E. E.; Kazandjian, D.; Dogan, A.; Zhang, Y.; Mikulasova, A.; Walker, B.; Morgan, G.; Campbell, P. J.; Landgren, O.; Rummens, J.-L.; Bolli, N.; Maura, F.
10.1101/2020.11.06.372011 — cancer biology — Posted on 2020-11-08
3103 The Effects of Strain and Estrous Cycle on Heroin- and Sucrose-Maintained Responding in Female Rats
Schmidt, K. T.; Sharp, J. L.; Ethridge, S. B.; Pearson, T.; Ballard, S.; Potter, K. M.; Smith, M. A.
10.1101/2020.11.06.370023 — animal behavior and cognition — Posted on 2020-11-08
3104 Mitotic interhomolog recombination drives genomic diversity in diatoms
Bulankova, P.; Sekulic, M.; Jallet, D.; Nef, C.; Delmont, T. O.; van Oosterhout, C.; Vercauteren, I.; Osuna-Cruz, C. M.; Vancaester, E.; Mock, T.; Sabbe, K.; Daboussi, F.; Bowler, C.; Vyverman, W.; Vandepoele, K.; De Veylder, L.
10.1101/2020.11.08.373134 — genomics — Posted on 2020-11-08
3105 Genomic Insights into the Demographic History of Southern Chinese
Huang, X.; Xia, Z.-Y.; Bin, X.; He, G.; Guo, J.; Lin, C.; Yin, L.; Zhao, J.; Ma, Z.; Ma, F.; Li, Y.; Hu, R.; Wei, L.-H.; Wang, C.-C.
10.1101/2020.11.08.373225 — genomics — Posted on 2020-11-08
3107 Viruses of the Thermotogota; the vehicles on the highways of gene sharing.
Haverkamp, T. H. A.; Lossouarn, J.; Zhaxybayeva, O.; Lyu, J.; Bienvenu, N.; Geslin, C.; Nesbo, C. L.
10.1101/2020.11.07.368316 — evolutionary biology — Posted on 2020-11-08
3111 Connecting omics signatures of diseases, drugs, and mechanisms of actions with iLINCS
Pilarczyk, M.; Kouril, M.; Shamsaei, B.; Vasiliauskas, J.; Niu, W.; Mahi, N. A.; Zhang, L.; Clark, N. A.; Ren, Y.; White, S.; Karim, R. S.; Xu, H.; Biesiada, J.; Bennett, M. F.; Davidson, S.; Reichard, J. F.; Roberts, K.; Stathias, V.; Koleti, A.; Vidovic, D.; Clarke, D. J. B.; Schurer, S. C.; Ma'ayan, A.; Meller, J.; Medvedovic, M.
10.1101/826271 — bioinformatics — Posted on 2020-11-08
3112 TSC1 loss-of-function increases risk for tauopathy by inducing tau acetylation and preventing autophagy-mediated tau clearance
Alquezar, C.; Schoch, K. M.; Geier, E. G.; Ramos, E. M.; Scrivo, A.; Li, K.; Argouarch, A. R.; Mlynarski, E. E.; Dombroski, B.; Yokoyama, J. S.; Cuervo, A. M.; Burlingame, A. L.; Schellenberg, G. D.; Miller, T. M.; Miller, B. L.; Kao, A. W.
10.1101/2020.11.08.371922 — neuroscience — Posted on 2020-11-08
3113 Intrusive Experiences In Post-Traumatic Stress Disorder: Treatment Response Induces Changes In The Effective Connectivity Of The Anterior Insula
Leroy, A.; Very, E.; Birmes, P.; Szaffarczyk, S.; Lopes, R.; Faure, C.; Duhem, S.; Grandgenevre, P.; Warembourg, F.; Vaiva, G.; Jardri, R.
10.1101/2020.10.01.319269 — neuroscience — Posted on 2020-11-08
3114 Clonal expansion of personalized anti-tumor T cells from circulation using tumor organoid-immune co-cultures
Meng, Q.; Xie, S.; Gray, K.; Li, W.; Huang, L.; Akshinthala, D.; Dezfulian, M.; Ferrer, E.; Conahan, C.; Del Pino, S.; Grossman, J.; Elledge, S.; Hidalgo, M.; Muthuswamy, S. K.
10.1101/2020.11.06.371807 — cancer biology — Posted on 2020-11-08
3118 Neuron-gated silicon nanowire field effect transistors to follow single spike propagation within neuronal network
Delacour, C.; Veliev, F.; Crozes, T.; Bres, G.; Minet, J.; Becq, G.; Ionica, I.; Ernst, T.; Briancon Marjollet, A.; Albrieux, M.; Villard, C.
10.1101/2020.11.06.371369 — bioengineering — Posted on 2020-11-08
3119 Micromechanical homogenisation of a hydrogel-filled electrospun scaffold for tissue-engineered epicardial patching of the infarcted heart
Abdalrahman, T.; Mandel, N.; Sack, K. L.; Pugno, N. M.; Bezuidenhout, D.; Limbert, G.; Moscato, F.; Davies, N. H.; Franz, T.
10.1101/2020.11.08.373209 — bioengineering — Posted on 2020-11-08
3122 Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer
Gupta, K.; Wen, Y.; Ninan, N. S.; Raimer, A. C.; Sharp, R.; Spring, A. M.; Sarachan, K. L.; Johnson, M. C.; Van Duyne, G. D.; Matera, A. G.
10.1101/2020.11.07.336172 — biochemistry — Posted on 2020-11-08
3124 Annual and 16-day rangeland production estimates for the western United States
Jones, M. O.; Robinson, N. P.; Naugle, D. E.; Maestas, J. D.; Reeves, M. C.; Lankston, R. W.; Allred, B. W.
10.1101/2020.11.06.343038 — ecology — Posted on 2020-11-08
3126 Interactions between axon-like projections extended by Drosophila Follicle Stem Cells dictate cell fate decisions
Lee, E. H.; Zinshteyn, D.; Wang, M.; Reinach, J.; Chau, C.; Costa, K.; Vargas, A.; Johnson, A.; Alexander, J. I.; O'Reilly, A. M.
10.1101/2020.11.07.372664 — developmental biology — Posted on 2020-11-08
3131 Synaptic dysfunction caused by truncated tau is associated with hyperpolarization-activated cyclic nucleotide-gated channelopathy
Goniotaki, D.; Tamagnini, F.; Biasetti, L.; Rumpf, S. L.; Fennell, K.; Pollack, S.; Ukwesa, S.; Sun, H.; Serpell, L.; Noble, W.; Staras, K.; Hanger, D.
10.1101/2020.11.08.369488 — neuroscience — Posted on 2020-11-08
3132 Cell type specific information transfer for sparse coding
Zeldenrust, F.; Calcini, N.; Yan, X.; Bijlsma, A.; Celikel, T.
10.1101/2020.11.06.371658 — neuroscience — Posted on 2020-11-08
3133 In-vivo histology of iron and myelin in the brain using magnetic susceptibility source separation in MRI
Shin, H.-G.; Lee, J.; Yun, Y. H.; Yoo, S. H.; Jang, J.; Oh, S.-H.; Nam, Y.; Jung, S.; Kim, S.; Fukunaga, M.; Kim, W.; Choi, H. J.; Lee, J.
10.1101/2020.11.07.363796 — neuroscience — Posted on 2020-11-08
3136 Epichloe festucae in mutualistic association with Lolium perenne suppresses host apoplastic cysteine protease activity
Passarge, A.; Demir, F.; Green, K.; Depotter, J. R. L.; Scott, B.; Huesgen, P. F.; Doehlemann, G.; Misas Villamil, J. C.
10.1101/2020.11.06.371211 — plant biology — Posted on 2020-11-08
3140 Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions
Mus, L. M.; Van Haver, S.; Popovic, M.; Trypsteen, W.; Lefever, S.; Zeltner, N.; Ogando, Y.; Jacobs, E. Z.; Denecker, G.; Sanders, E.; Van Neste, C.; Vanhauwaert, S.; Decaesteker, B.; Deforce, D.; Van Nieuwerburgh, F.; Mestdagh, P.; Vandesompele, J.; Menten, B.; De Preter, K.; Studer, L.; Heindryckx, B.; Durinck, K.; Roberts, S.; Speleman, F.
10.1101/2020.11.06.360685 — cancer biology — Posted on 2020-11-08
3141 Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
Song, H.; Weinstein, H. N. W.; Allegakoen, P.; Wadsworth, M. H.; Xie, J.; Yang, H.; Feng, F. Y.; Carroll, P. R.; Wang, B.; Cooperberg, M. R.; Shalek, A. K.; Huang, F. W.
10.1101/2020.11.06.359802 — cancer biology — Posted on 2020-11-08
3146 CoBRA: Containerized Bioinformatics workflow for Reproducible ChIP/ATAC-seq Analysis - from differential peak calling to pathway analysis
Qiu, X.; Feit, A.; Feiglin, A.; Xie, Y.; Kesten, N.; Taing, L.; Perkins, J.; Zhou, N.; Gu, S.; Li, Y.; Cejas, P.; Jeselsohn, R.; Brown, M.; Liu, X. S.; Long, H. W.
10.1101/2020.11.06.367409 — bioinformatics — Posted on 2020-11-08
3148 Optimizing Consensus Generation Algorithms for Highly Variable Amino Acid Sequence Clusters
Mohabati, R.; Rezaei, R.; Mohajel, N.; Ranjbar, M. M.; Azadmanesh, K.; Roohvand, F.
10.1101/2020.11.08.373092 — bioinformatics — Posted on 2020-11-08
3152 VTAM: A robust pipeline for validating metabarcoding data using internal controls
Gonzalez, A.; Dubut, V.; Corse, E.; Mekdad, R.; Dechatre, T.; Meglecz, E.
10.1101/2020.11.06.371187 — ecology — Posted on 2020-11-08
3155 Surfaceome CRISPR Screen Identifies OLFML3 as a Rhinovirus-inducible IFN Antagonist
Mei, H.; Zha, Z.; Wang, W.; Xie, Y.; Huang, Y.; Li, W.; Wei, D.; Zhang, X.; Xie, J.; Qu, M.; Liu, J.
10.1101/2020.11.08.372607 — molecular biology — Posted on 2020-11-08
3157 Widespread Polymodal Chemosensory Receptor Expression in Drosophila Olfactory Neurons
Task, D.; Lin, C.-C.; Afify, A.; Li, H.; Vulpe, A.; Menuz, K.; Potter, C. J.
10.1101/2020.11.07.355651 — neuroscience — Posted on 2020-11-08
3158 Non-canonical odor coding ensures unbreakable mosquito attraction to humans
Younger, M. A.; Herre, M.; Ehrlich, A. R.; Gong, Z.; Gilbert, Z. N.; Rahiel, S.; Matthews, B. J.; Vosshall, L. B.
10.1101/2020.11.07.368720 — neuroscience — Posted on 2020-11-08
3160 Improved bioavailability of montelukast through a novel oral mucoadhesive film in humans and mice
Michael, J.; de Sousa, D. M.; Conway, J.; Gonzalez-Labrada, E.; Obeid, R.; Tevini, J.; Felder, T.; Hutter-Paier, B.; Zerbe, H.; Paiement, N.; Aigner, L.
10.1101/2020.11.06.371500 — pharmacology and toxicology — Posted on 2020-11-08
3162 Genetic factors influencing a neurobiological substrate for psychiatric disorders
Andlauer, T. F. M.; Mühleisen, T. W.; Hoffstaedter, F.; Teumer, A.; Wittfeld, K.; Teuber, A.; Reinbold, C. S.; Grotegerd, D.; Bülow, R.; Caspers, S.; Dannlowski, U.; Herms, S.; Hoffmann, P.; Kircher, T.; Minnerup, H.; Moebus, S.; Nenadic, I.; Teismann, H.; Völker, U.; International FTD-Genomics Consortium (IFGC), ; The 23andMe Research Team, ; Etkin, A.; Berger, K.; Grabe, H. J.; Nöthen, M. M.; Amunts, K.; Eickhoff, S. B.; Sämann, P. G.; Müller-Myhsok, B.; Cichon, S.
10.1101/774463 — genetics — Posted on 2020-11-08
3167 Implementing the precautionary approach into fisheries management: Making the case for probability-based harvest control rules
Mildenberger, T.; Berg, C. W.; Kokkalis, A.; Hordyk, A. R.; Wetzel, C.; Jacobsen, N. S.; Punt, A. E.; Nielsen, J. R.
10.1101/2020.11.06.369785 — ecology — Posted on 2020-11-08
3169 Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk
Twigger, A.-J.; Engelbrecht, L. K.; Bach, K.; Schultz-Pernice, I.; Petricca, S.; Scheel, C. H.; Khaled, W.
10.1101/2020.11.06.371443 — cell biology — Posted on 2020-11-08
3170 Genetic composition and evolution of the prevalent Mycobacterium tuberculosis lineages 2 and 4 in the Chinese and Zhejiang Province populations
Wu, B.; Zhu, W.; Wang, Y.; Wang, Q.; Zhou, L.; Liu, Z. W.; Bi, L.; Barun, M.; Kreiswirth, B. N.; Chen, L.; Chen, S.; Wang, X.; Wang, W.
10.1101/2020.11.07.372573 — molecular biology — Posted on 2020-11-08
3171 Simultaneous, cell-intrinsic downregulation of PD-1 and TIGIT enhances the effector function of CD19-targeting CAR T cells and promotes an early-memory phenotype
Lee, Y.; Lee, H. J.; Kim, H. C.; Lee, Y.; Nam, S. K.; Hupperetz, C.; Ma, J. S.; Wang, X.; Singer, O.; Kim, W. S.; Kim, S. J.; Koh, Y.; Jung, I.; Kim, C. H.
10.1101/2020.11.07.372334 — immunology — Posted on 2020-11-08
3172 K+ efflux through postsynaptic NMDA receptors suppresses local astrocytic glutamate uptake
Tyurikova, O.; Shih, P.-Y.; Dembitskaya, Y.; Savtchenko, L. P.; McHugh, T.; Rusakov, D. A.; Semyanov, A.
10.1101/2020.11.07.372722 — neuroscience — Posted on 2020-11-08
3173 MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
Takado, Y.; Takuwa, H.; Sampei, K.; Urushihata, T.; Takahashi, M.; Shimojo, M.; Uchida, S.; Nitta, N.; Shibata, S.; Nagashima, K.; Ochi, Y.; Ono, M.; Maeda, J.; Tomita, Y.; Sahara, N.; Near, J.; Aoki, I.; Shibata, K.; Higuchi, M.
10.1101/2020.10.25.353888 — neuroscience — Posted on 2020-11-08
3175 Function and regulation of chloroplast peroxiredoxin IIE
Dreyer, A.; Treffon, P.; Basiry, D.; Jozefowicz, A. M.; Matros, A.; Mock, H.-P.; Dietz, K.-J.
10.1101/2020.11.06.370908 — plant biology — Posted on 2020-11-08
3177 Target-driven design of a coumarinyl chalcone scaffold based novel EF2 Kinase inhibitor suppresses breast cancer growth in vivo
Comert Onder, F.; Kahraman, N.; Bellur Atici, E.; Cagir, A.; Kandemir, H.; Tatar, G.; Taskin Tok, T.; Karliga, B.; Durdagi, S.; Ay, M.; Ozpolat, B.
10.1101/2020.11.06.371062 — cancer biology — Posted on 2020-11-08
3183 Molecular hallmarks of heterochronic parabiosis at single cell resolution
Palovics, R.; Keller, A.; Schaum, N.; Tan, W.; Fehlmann, T.; Borja, M.; Webber, J.; McGeever, A.; Bonanno, L.; The Tabula Muris Consortium, ; Pisco, A. O.; Karkanias, J.; Neff, N. F.; Darmanis, S.; Quake, S. R.; Wyss-Coray, T.
10.1101/2020.11.06.367078 — genomics — Posted on 2020-11-08
3187 NtrX systemically controls transcription of the CtrA system genes to regulate Rhizobium cell division
Luo, L.; Xing, S.; An, F.; Yang, X.; Huang, L.; Zeng, S.; Li, N.; Ouenzar, K.; Yan, J.; Yu, L.
10.1101/2020.11.06.341933 — molecular biology — Posted on 2020-11-08
3188 Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila
Nabeel-Shah, S.; Garg, J.; Saettone, A.; Ashraf, K.; Lee, H.; Wahab, S.; Ahmed, N.; Fine, J.; Derynck, J.; Ponce, M.; Pu, S.; Marcon, E.; Zhang, Z.; Greenblatt, J. F.; Pearlman, R. E.; Lambert, J.-P.; Fillingham, J.
10.1101/2020.11.07.372946 — molecular biology — Posted on 2020-11-08
3191 Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization
Liu, Z.; VanBlargan, L. A.; Rothlauf, P. W.; Bloyet, L.-M.; Chen, R. E.; Stumpf, S.; Zhao, H.; Errico, J. M.; Theel, E. S.; Ellebedy, A. H.; Fremont, D. H.; Diamond, M. S.; Whelan, S. P. J.
10.1101/2020.11.06.372037 — microbiology — Posted on 2020-11-08
3193 Phosphorylation of the canonical histone H2A marks foci of damaged DNA in malaria parasite
Goyal, M.; Heinberg, A.; Mitesser, V.; Kandelis-Shalev, S.; Singh, B. K.; Dzikowski, R.
10.1101/2020.11.06.372391 — microbiology — Posted on 2020-11-08
3196 Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
Brouwer, P. J. M.; Brinkkemper, M.; Maisonnasse, P.; Dereuddre-Bosquet, N.; Grobben, M.; Claireaux, M.; de Gast, M.; Marlin, R.; Chesnais, V.; Diry, S.; Allen, J. D.; Watanabe, Y.; Griezen, J. M.; Kerster, G.; Turner, H. L.; van der Straten, K.; van der Linden, C. A.; Aldon, Y.; Naninck, T.; Bontjer, I.; Burger, J. A.; Poniman, M.; Mykytyn, A. Z.; Okba, N. M. A.; Schermer, E. E.; van Breemen, M. J.; Ravichandran, R.; Caniels, T. G.; van Schooten, J.; Kahlaoui, N.; Contreras, V.; Lemaitre, J.; Chapon, C.; Ho Tsong Fang, R.; Villaudy, J.; Sliepen, K.; van der Velden, Y. U.; Haagmans, B.; de Bree
10.1101/2020.11.07.365726 — immunology — Posted on 2020-11-08
3197 Transarterial embolization modulates the immune response within target and non-target hepatocellular carcinomas.
Tischfield, D.; Gurevich, A.; Johnson, O.; Gayatman, I.; Nadolski, G.; Kaplan, D.; Furth, B.; Hunt, S.; Gade, T.
10.1101/2020.11.07.372896 — immunology — Posted on 2020-11-08
3198 Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed
Shibata, T.; Shah, S.; Evans, T.; Coleman, H. N.; Lieblong, B. J.; Spencer, H. J.; Quick, C. M.; Sasagawa, T.; Stephens, O. W.; Peterson, E.; Johann, D.; Lu, Y.-C.; Nakagawa, M.
10.1101/2020.11.07.364844 — immunology — Posted on 2020-11-08
3199 A zebrafish model for COVID-19 recapitulates olfactory and cardiovascular pathophysiologies caused by SARS-CoV-2
Kraus, A.; Casadei, E.; Huertas, M.; Ye, C.; Bradfute, S. B.; Boudinot, P.; Levraud, J.-P.; Salinas, I.
10.1101/2020.11.06.368191 — immunology — Posted on 2020-11-08
3200 Variability of Accessory Proteins Rules the SARS-CoV-2 Pathogenicity
Hassan, S. S.; Pal Choudhury, P.; Uversky, V. N.; Dayhoff, G. W.; Aljabali, A. A. A.; Uhal, B.; Lundstrom, K.; Rezaei, N.; Seyran, M.; Pizzol, D.; Adadi, P.; Lal, A.; Soares, A.; Abd El-Aziz, T. M.; Kandimalla, R.; Tambuwala, M.; Azad, G. K.; Sherchan, S. P.; Baetas-da-Cruz, W.; Takayama, K.; Serrano Aroca, A.; Chauhan, G.; Palu, G.; Brufsky, A.
10.1101/2020.11.06.372227 — bioinformatics — Posted on 2020-11-08
3202 A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
Szabo, A.; Akkouh, I. A.; Vandenberghe, M.; Osete, J. R.; Hughes, T.; Heine, V.; Smeland, O. B.; Glover, J. C.; Andreassen, O.; Djurovic, S.
10.1101/2020.11.07.372839 — neuroscience — Posted on 2020-11-07
3203 Ferroportin 3 is a dual-targeted mitochondrial/chloroplast iron exporter necessary for iron homeostasis in Arabidopsis
Kim, L. J.; Tsuyuki, K. M.; Hu, F.; Park, E. Y.; Zhang, J.; Gallegoe Iraheta, J.; Chia, J.-C.; Huang, R.; Tucker, A. E.; Clyne, M.; Castellano, C.; Kim, A.; Chung, D. D.; DaVeiga, C. T.; Parsons, E. M.; Vatamaniuk, O. K.; Jeong, J.
10.1101/2020.07.15.203646 — plant biology — Posted on 2020-11-07
3206 Complex population structure of the Atlantic puffin revealed by whole genome analyses
Kersten, O.; Star, B.; Leigh, D. M.; Anker-Nilssen, T.; Stroem, H.; Danielsen, J.; Descamps, S.; Erikstad, K. E.; Fitzsimmons, M. G.; Fort, J.; Hansen, E. S.; Harris, M. P.; Irestedt, M.; Kleven, O.; Mallory, M. L.; Jakobsen, K. S.; Boessenkool, S.
10.1101/2020.11.05.351874 — genomics — Posted on 2020-11-07
3209 Bayesian model selection favors parametric over categorical fMRI subsequent memory models in young and older adults
Soch, J.; Richter, A.; Schuetze, H.; Kizilirmak, J. M.; Assmann, A.; Knopf, L.; Raschick, M.; Schult, A.; Maass, A.; Ziegler, G.; Richardson-Klavehn, A.; Duezel, E.; Schott, B. H.
10.1101/2020.07.27.220871 — neuroscience — Posted on 2020-11-07
3211 βPix sequesters IDOL and prevents LDL receptor degradation through a β2AR-regulated signaling pathway in Alport Syndrome
Chahdi, A.; Yousefi, K.; Capcha, J. M. C.; Irion, C. I.; Lambert, G.; Shehadeh, S. A.; Dunkley, J. C.; Lee, Y.-S.; Khan, A.; Ramic, M.; De Andrade, N. S.; Zeier, Z.; Dykxhoorn, D.; Katsoufis, C. P.; Freundlich, M.; Hare, J. M.; Nabity, M. B.; Rivera, C.; Lymperopoulos, A.; Shehadeh, L. A.
10.1101/2020.11.06.372292 — molecular biology — Posted on 2020-11-07
3214 Candidate Explorer: a tool for discovery, evaluation, and display of mutations causing significant immune phenotypes
Xu, D.; Lyon, S.; Bu, C. H.; Hildebrand, S.; Choi, J. H.; Zhong, X.; Liu, A.; Turer, E. E.; Zhang, Z.; Nair-Gill, E.; Shi, H.; Wang, Y.; Zhang, D.; Yue, T.; SoRelle, J.; Misawa, T.; Sun, L.; Wang, J.; Farokhnia, R.; Sakla, A.; Schneider, S.; Stewart, N.; Coco, H.; Coolbaugh, G.; Hayse, B.; Mazal, S.; Medler, D.; Nguyen, B.; Rodriguez, E.; Wadley, A.; Tang, M.; Li, X.; Anderton, P.; Keller, K.; Scott, L.; Quan, J.; Cooper, S.; Qin, B.; Cardin, J.; Simpson, R.; Tadesse, M.; Sun, Q.; Santoyo, J.; Bronikowski, A.; Johnson, A.; Moresco, E. M. Y.; Beutler, B.
10.1101/2020.11.07.371914 — genetics — Posted on 2020-11-07
3215 TRAF6 and TAK1 contribute to SAMHD1-mediated negative regulation of NF-kB signaling
Espada, C. E.; St. Gelais, C.; Bonifati, S.; Maksimova, V. V.; Cahill, M. P.; Kim, S. H.; Wu, L.
10.1101/2020.11.07.368704 — microbiology — Posted on 2020-11-07
3216 Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo
Dominguez Meijide, A.; Parrales, V.; Vasili, E.; Gonzalez-Lizarraga, F.; König, A.; Lazaro, D. F.; Lannuzel, A.; Haik, S.; Del-Bel, E. A.; Chehin, R.; Raisman-Vozari, R.; Michel, P. P.; Bizat, N.; Outeiro, T. F.
10.1101/2020.11.06.371229 — molecular biology — Posted on 2020-11-07
3219 European Primary Forest Database (EPFD) v2.0
Sabatini, F. M.; Bluhm, H.; Kun, Z.; Aksenov, D.; Atauri, J. A.; Buchwald, E.; Burrascano, S.; Cateau, E.; Diku, A.; Marques Duarte, I.; Fernandez Lopez, A. B.; Garbarino, M.; Grigoriadis, N.; Horvath, F.; Keren, S.; Kitenberga, M.; Kis, A.; Kraut, A.; Ibisch, P. L.; Larrieu, L.; Lombardi, F.; Matovic, B.; Melu, R. N.; Meyer, P.; Midteng, R.; Mikac, S.; Mikolas, M.; Mozgeris, G.; Panayotov, M.; Pisek, R.; Nunes, L.; Ruete, A.; Schickhofer, M.; Simovski, B.; Stillhard, J.; Stojanovic, D.; Szwagrzyk, J.; Tikkanen, O.-P.; Toromani, E.; Volosyanchuk, R.; Vrska, T.; Waldherr, M.; Yermokhin, M.; Zla
10.1101/2020.10.30.362434 — ecology — Posted on 2020-11-07
3221 Phylogenomics of scorpions reveal a co-diversification of scorpion mammalian predators and mammal-specific sodium channel toxins
Sanitbanez-Lopez, C. E.; Aharon, S.; Ballesteros, J. A.; Gainett, G.; Baker, C. M.; Gonzalez-Santillan, E.; Harvey, M. S.; Hassan, M. K.; Abu-Almaaty, A. H.; Aldeyarbi, S. M.; Monod, L.; Ojanguren-Affilastro, A.; Raven, R. J.; Pinto-da-Rocha, R.; Zvik, Y.; Gavish-Regev, E.; Sharma, P. P.
10.1101/2020.11.06.372045 — evolutionary biology — Posted on 2020-11-07
3224 A novel Mn-dependent peroxidase contributes to tardigrade anhydrobiosis
Yoshida, Y.; Satoh, T.; Ota, C.; Tanaka, S.; Horikawa, D.; Tomita, M.; Kato, K.; Arakawa, K.
10.1101/2020.11.06.370643 — molecular biology — Posted on 2020-11-07
3227 Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design
Weber, L. M.; Hippen, A. A.; Hickey, P. F.; Berrett, K. C.; Gertz, J.; Doherty, J. A.; Greene, C. S.; Hicks, S. C.
10.1101/2020.11.06.371963 — bioinformatics — Posted on 2020-11-07
3229 Finger Sweat Analysis Enables Short Interval Metabolic Biomonitoring in Humans
Brunmair, J.; Niederstaetter, L.; Neuditschko, B.; Bileck, A.; Slany, A.; Janker, L.; Feuerstein, M. L.; Langbauer, C.; Gotsmy, M.; Zanghellini, J.; Meier-Menches, S. M.; Gerner, C.
10.1101/2020.11.06.369355 — biochemistry — Posted on 2020-11-07
3230 Fluorescent Antibody Multiplexing with Oligo-Based Combinatorial Labeling
McCarthy, M.; Anglin, C.; Pear, H.; Boleman, S.; Klaubert, S.; Birtwistle, M. R.
10.1101/2020.11.06.371906 — biochemistry — Posted on 2020-11-07
3231 Visualising Cholesterol in Brain by On-Tissue Derivatisation and Quantitative Mass Spectrometry Imaging
Angelini, R.; Yutuc, E.; Wyatt, M. F.; Newton, J.; Yusuf, F. A.; Griffiths, L.; Cooze, B. J.; El Assad, D.; Frache, G.; Rao, W.; Allen, L. B.; Korade, Z.; Nguyen, T. T.; Rathnayake, R. A.; Cologna, S. M.; Howell, O. W.; Clench, M. R.; Wang, Y.; Griffiths, W. J.
10.1101/2020.11.06.369447 — biochemistry — Posted on 2020-11-07
3235 Glypicans specifically regulate Hedgehog signaling through their interaction with Ihog in cytonemes
Simon, E.; Jimenez-Jimenez, C.; Seijo-Barandiaran, I.; Aguilar, G.; Sanchez-Hernandez, D.; Aguirre-Tamaral, A.; Gonzalez-Mendez, L.; Ripoll, P.; Guerrero, I.
10.1101/2020.11.04.367797 — developmental biology — Posted on 2020-11-07
3236 Hedgehog signalling regulates patterning of the murine and human dentitions through Gas1 co-receptor function
Seppala, M. H.-M.; Thivichon-Prince, B.; Xavier, G. G. M.; Shaffie, N.; Sangani, I.; Birjandi, A. A.; Rooney, J.; Lau, J. N. S.; Dhalivar, R.; Rossi, O.; Riaz, A.; Stonehouse-Smith, D.; Wang, Y.; Viriot, L.; Cobourne, M. T.
10.1101/2020.11.06.371476 — developmental biology — Posted on 2020-11-07
3237 Cryo-EM structure of the mature and infective Mayaro virus at 4.4 A resolution reveals new features of arthritogenic alphaviruses
Filho, H. R.; Coimbra, L. D.; Cassago, A.; Rocha, R. P. F.; Padilha, A. C.; Guerra, J. V. d. S.; Leme, L.; Trivella, D. B. B.; Portugal, R. V.; Lopes-de-Oliveira, P. S.; Marques, R. E.
10.1101/2020.11.06.371773 — microbiology — Posted on 2020-11-07
3238 The unintended consequences of a surge in antibiotic resistance when removing wastewater drain biofilm
KOTAY, S. M.; Parikh, H. I.; Gweon, H. S.; Barry, K.; Stoesser, N.; Walker, A. S.; Crook, D. W.; Vegesana, K.; Mathers, A. J.
10.1101/2020.11.06.372326 — microbiology — Posted on 2020-11-07
3239 The impact of Staphylococcus aureus cell wall glycosylation on langerin recognition and Langerhans cell activation
Hendriks, A.; van Dalen, R.; Ali, S.; Gerlach, D.; van der Marel, G. A.; Fuchsberger, F. F.; Aerts, P.; de Haas, C. J. C.; Peschel, A.; Rademacher, C.; van Strijp, J.; Codee, J. D.; van Sorge, N. M.
10.1101/2020.11.06.371559 — microbiology — Posted on 2020-11-07
3240 The spatial-temporal dynamics of respiratory syncytial virus infections across the east-west coasts of Australia during 2016-17
Robertson, M.; Eden, J.-S.; Levy, A.; Carter, I.; Tulloch, R. L.; Cutmore, E. J.; Horsburgh, B. A.; Sikazwe, C. T.; Dwyer, D. E.; Smith, D. W.; Kok, J.
10.1101/2020.11.06.372177 — microbiology — Posted on 2020-11-07
3241 Immunoregulatory effects of Imuno TF (transfer factors) on Th1/Th2/Th17/Treg cytokines
Oliveira, C. R.; Vieira, R. P.; Ferreira, A. d. O.; Goncalves, A. E. d. S. S.; Polonini, H.
10.1101/2020.11.06.371435 — immunology — Posted on 2020-11-07
3243 Matchathon: A guide to student-faculty connections in PhD programs
Amemiya, H. M.; Lapp, Z.; Smith, C. S.; Durdan, M. M.; DiMondo, M.; Bodiya, B.; Barolo, S.
10.1101/2020.11.06.371526 — scientific communication and education — Posted on 2020-11-07
3244 An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding
Bartsch, A.; Ives, C. M.; Kattner, C.; Pein, F.; Tanabe, M.; Munk, A.; Zachariae, U.; Steinem, C.; Llabres, S.
10.1101/2020.11.06.369579 — biophysics — Posted on 2020-11-07
3247 Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of Aspergillus fumigatus
Steenwyk, J. L.; Mead, M. E.; Castro, P. A.; Valero, C.; Damasio, A.; Santos, R. A. C.; LaBella, A. L.; Li, Y.; Knowles, S. L.; Raja, H. A.; Oberlies, N. H.; Zhou, X.; Cornely, O. A.; Fuchs, F.; Koehler, P.; Goldman, G.; Rokas, A.
10.1101/2020.11.06.371971 — microbiology — Posted on 2020-11-06
3250 The host exocyst complex is targeted by a conserved bacterial type III effector protein that promotes virulence
A. Michalopoulou, V. A.; Kotsaridis, K.; Mermigka, G.; Kotsifaki, D.; Kokkinidis, M.; Celie, P. H. N.; Jones, J. D. G.; Sarris, P. F.
10.1101/2020.11.06.371260 — microbiology — Posted on 2020-11-07
3253 Differing impacts of global and regional responses on SARS-CoV-2 transmission cluster dynamics
Rife Magalis, B.; Ramirez-Mata, A.; Zhukova, A.; Mavian, C.; Marini, S.; Lemoine, F.; Prosperi, M.; Gascuel, O.; Salemi, M.
10.1101/2020.11.06.370999 — genomics — Posted on 2020-11-06
3254 Whole genome sequencing for diagnosis of neurological repeat expansion disorders
Ibanez, K.; Polke, J.; Hagelstrom, T.; Dolzhenko, E.; Pasko, D.; Thomas, E.; Daugherty, L.; Kasperaviciute, D.; McDonagh, E. M.; Smith, K. R.; Rueda Martin, A.; Polychronopoulos, D.; Angus-Leppan, H.; Bhatia, K. P.; Davison, J. E.; Festenstein, R.; Fratta, P.; Giunti, P.; Howard, R.; Korlipara, L. V. P.; Laura, M.; McEntagart, M.; Menzies, L.; Morris, H.; Reilly, M. M.; Robinson, R.; Rosser, E.; Faravelli, F.; Schrag, A.; Schott, J. M.; Warner, T. T.; Wood, N. W.; Bourn, D.; Eggleton, K.; Labrum, R.; Twiss, P.; Abbs, S.; Santos, L.; Almheiri, G.; Sheikh, I.; Vandrovcova, J.; Patch, C.; Tavares
10.1101/2020.11.06.371716 — genomics — Posted on 2020-11-06
3257 The oxidative stress response and virulence of pathogenic Leptospira are controlled by the interplay of two peroxide stress regulators
Zavala-Alvarado, C.; Vincent, A. T.; Sismeiro, O.; Legendre, R.; Varet, H.; Bussotti, G.; Lorioux, C.; Coppee, J.-Y.; Veyrier, F. J.; Picardeau, M.; Benaroudj, N.
10.1101/2020.11.06.371039 — microbiology — Posted on 2020-11-06
3258 Rhinovirus reduces the severity of subsequent respiratory viral infections, which is associated with dampened inflammatory responses
Van Leuven, J. T.; Gonzalez, A. J.; Wixom, A. Q.; Clary, J. L.; Ridenhour, B. J.; Miller, C. R.; Miura, T. A.
10.1101/2020.11.06.371005 — microbiology — Posted on 2020-11-06
3259 Persistence of SARS-CoV-2 specific B- and T-cell responses in convalescent COVID-19 patients 6-8 months after the infection
Sherina, N.; Piralla, A.; Du, L.; Wan, H.; Kumagai-Braesh, M.; Andrell, J.; Braesch-Andersen, S.; Cassaniti, I.; Percivalle, E.; Sarasini, A.; Bergami, F.; Di Martino, R.; Colaneri, M.; Vecchia, M.; Sambo, M.; Zuccaro, V.; Bruno, R.; Oggionni, T.; Meloni, F.; Abolhassani, H.; Bertoglio, F.; Schubert, M.; Byrne-Steele, M.; Han, J.; Hust, M.; Xue, Y.; Hammarstrom, L.; Baldanti, F.; Marcotte, H.; Pan-Hammarstrom, Q.
10.1101/2020.11.06.371617 — immunology — Posted on 2020-11-06
3262 Genome-wide analysis of long noncoding RNAs, 24-nt siRNAs, DNA methylation and H3K27me3 marks in Brassica rapa and related species
Mehraj, H.; Shea, D. J.; Takahashi, S.; Miyaji, N.; Akter, A.; Seki, M.; Dennis, E. S.; Fujimoto, R.; Osabe, K.
10.1101/2020.11.06.370940 — plant biology — Posted on 2020-11-06
3264 The Genomic History of the Middle East
Almarri, M. A.; Haber, M.; Lootah, R. A.; Hallast, P.; Al Turki, S.; Martin, H. C.; Xue, Y.; Tyler-Smith, C.
10.1101/2020.10.18.342816 — genomics — Posted on 2020-11-06
3266 Badger territoriality maintained despite disturbance of major road construction
Gaughran, A.; Mullen, E.; MacWhite, T.; Maher, P.; Kelly, D. J.; Kelly, R.; Good, M.; Marples, N. M.
10.1101/2020.11.06.370957 — ecology — Posted on 2020-11-06
3267 Stem Cell Transplantation Rescued A Primary Open-Angle Glaucoma Mouse Model
Xiong, S.; Kumar, A.; Tian, S.; Taher, E.; Yang, E.; Kinchington, P. R.; Xia, X.; Du, Y.
10.1101/2020.02.04.934448 — cell biology — Posted on 2020-11-06
3268 Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality
Navare, A. T.; Mast, F. D.; Olivier, J. P.; Bertomeu, T. D.; Carpp, L. N.; Kaushansky, A.; Coulombe-Huntington, J.; Neal, M.; Tyers, M.; Aitchison, J. D.
10.1101/2020.10.12.336487 — molecular biology — Posted on 2020-11-06
3270 Delta- and theta-band cortical tracking and phase-amplitude coupling to sung speech by infants
Attaheri, A.; Ni Choisdealbha, A.; Di Liberto, G.; Rocha, S.; Brusini, P.; Mead, N.; Olawole-Scott, H.; Boutris, P.; Gibbon, S.; Williams, I.; Grey, C.; Flanagan, S.; Goswami, U.
10.1101/2020.10.12.329326 — neuroscience — Posted on 2020-11-06
3271 Fine-mapping the consequences of site-specific glycan installation by shotgun scanning glycomutagenesis
Li, M.; Zheng, X.; Shanker, S.; Jaroentomeechai, T.; Kocer, I.; Byrne, J.; Cox, E. C.; Fu, Q.; Zhang, S.; Labonte, J. W.; Gray, J. J.; DeLisa, M. P.
10.1101/2020.06.28.176198 — synthetic biology — Posted on 2020-11-06
3273 Streamlining Data-Intensive Biology With Workflow Systems
Reiter, T.; Brooks, P. T.; Irber, L.; Joslin, S. E. K.; Reid, C. M.; Scott, C.; Brown, C. T.; Pierce, N. T.
10.1101/2020.06.30.178673 — bioinformatics — Posted on 2020-11-06
3274 Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes
Vysotskiy, M.; Zhong, X.; Miller-Fleming, T. W.; Zhou, D.; Autism Working Group of the Psychiatric Genomics Consortium, ; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Schizophrenia Working Group of the Psychiatric Genomics Consortium, ; Cox, N. J.; Weiss, L. A.
10.1101/2020.06.23.166181 — genetics — Posted on 2020-11-06
3276 Single-cell transcriptome profiling of an adult human cell atlas of 15 major organs
He, S.; Wang, L.-H.; Liu, Y.; Li, Y.-Q.; Chen, H.-T.; Xu, J.-H.; Peng, W.; Lin, G.-W.; Wei, P.-P.; Li, B.; Xia, X.; Wang, D.; Bei, J.-X.; He, X.; Guo, Z.
10.1101/2020.03.18.996975 — cell biology — Posted on 2020-11-06
3277 Human Chr18: "Stakhanovite" Genes, Missing and uPE1 Proteins in Liver Tissue and HepG2 Cells
Krasnov, G. S.; Lisitsa, A. V.; Ponomarenko, E. A.; Radko, S. P.; Ptitsyn, K. G.; Shapovalova, V. V.; Timoshenko, O. S.; Khmeleva, S. A.; Kurbatov, L. K.; Kiseleva, Y. Y.; Ilgisonis, E. V.; Pyatnitskiy, M. A.; Poverennaya, E. V.; Kiseleva, O. I.; Vakhrushev, I. V.; Tsvetkova, A. V.; Buromski, I. V.; Markin, S. S.; Zgoda, V. G.; Archakov, A. I.
10.1101/2020.11.04.358739 — molecular biology — Posted on 2020-11-06
3278 Transcription and splicing dynamics during early Drosophila development
Prudencio, P.; Rebelo, K.; Savisaar, R.; Martinho, R. G.; Carmo-Fonseca, M.
10.1101/2020.11.05.367888 — molecular biology — Posted on 2020-11-06
3280 Phage recombination drives evolution of spore-forming Bacilli
Dragos, A.; B, P.; Hasan, Z.; Lenz-Strube, M.; Kempen, P. J.; Maroti, G.; Kaspar, C.; Bose, B.; Burton, B.; Bischofs, I. B.; Kovacs, A. T.
10.1101/2020.05.06.055103 — microbiology — Posted on 2020-11-06
3281 Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
Gallegos-Monterrosa, R.; Nordgaard Christensen, M.; Barchewitz, T.; Koppenhoefer, S.; Priyadarshini, B.; Balint, B.; Maroti, G.; Kempen, P. J.; Dragos, A.; Kovacs, A. T.
10.1101/2020.09.01.278184 — microbiology — Posted on 2020-11-06
3282 Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer's disease mouse model
Muraoka, S.; Jedrychowski, M. P.; Iwahara, N.; Abdullah, M.; Onos, K. D.; Keezer, K. J.; Hu, J.; Ikezu, S.; Howell, G. R.; Gygi, S. P.; Ikezu, T.
10.1101/2020.11.05.369728 — neuroscience — Posted on 2020-11-06
3283 A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
Vizioli, L.; Moeller, S.; Dowdle, L.; Akcakaya, M.; De Martino, F.; Yacoub, E.; Ugurbil, K.
10.1101/2020.11.04.368357 — neuroscience — Posted on 2020-11-06
3285 Cellular mRNA signals in human kidney tumors
Young, M. D.; Mitchell, T. J.; Custers, L. M.; Margaritis, T.; Morales, F.; Kwakwa, K.; Khabirova, E.; Kildisiute, G.; Oliver, T. R.; Krijger, R. R. d.; Heuvel-Eibrink, M. M. v. d.; Comitani, F.; Piapi, A.; Blanco, E. B.; Thevanesan, C.; Burke, C.; Prigmore, E.; Ambridge, K.; Roberts, K.; Braga, F. A. V.; Coorens, T. H.; Valle, I. D.; Wilbrey-Clark, A.; Mamanova, L.; Stewart, G. D.; Gnanapragasam, V. J.; Rampling, D.; Sebire, N.; Coleman, N.; Hook, L.; Warren, A.; Haniffa, M.; Kool, M.; Pfister, S. M.; Achermann, J. C.; He, X.; Barker, R. A.; Shlien, A.; Bayraktar, O. A.; Teichmann, S.; Holste
10.1101/2020.03.19.998815 — cancer biology — Posted on 2020-11-06
3286 Strengthening the BioCompute Standard by Crowdsourcing on PrecisionFDA
Stephens, S. H.; King, C. H.; Watford, S.; Patel, J.; Dean, D. A.; Koc, S.; Xiao, N.; Donaldson, E. F.; Thompson, E. E.; Purkayastha, A.; Mazumder, R.; Johanson, E.; Keeney, J.
10.1101/2020.11.02.365528 — bioinformatics — Posted on 2020-11-06
3288 Development of Optically-Controlled "Living Electrodes" with Long-Projecting Axon Tracts for a Synaptic Brain-Machine Interface
Adewole, D. O.; Struzyna, L. A.; Burrell, J. C.; Harris, J. P.; Nemes, A. D.; Petrov, D.; Kraft, R. H.; Chen, H. I.; Serruya, M. D.; Wolf, J. A.; Cullen, D. K.
10.1101/333526 — bioengineering — Posted on 2020-11-06
3289 H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Cai, Y.; Zhang, Y.; Loh, Y. P.; Tng, J. Q.; Lim, M. C.; Cao, Z.; Raju, A.; Aiden, E. L.; Li, S.; Manikandan, L.; Tergaonkar, V.; Tucker-Kellogg, G.; Fullwood, M. J.
10.1101/684712 — genomics — Posted on 2020-11-06
3293 Sclerostin depletion induces inflammation in the bone marrow of mice
Donham, C.; Chicana, B.; Robling, A. G.; Mohamed, A.; Elizaldi, S.; Chi, M.; Freeman, B.; Millan, A.; Murguesh, D.; Loots, G. G.; Manilay, J. O.
10.1101/2020.11.01.364158 — immunology — Posted on 2020-11-06
3294 TOLLIP resolves lipid-induced EIF2 signaling in alveolar macrophages for durable Mycobacterium tuberculosis protection.
Venkatasubramanian, S.; Plumlee, C.; Dill-McFarland, K.; Pearson, G.; Cohen, S. B.; Lietzke, A.; Hinderstein, S. A.; Pryor, R.; Soleimanpour, S. A.; Altman, M.; Urdahl, K. B.; Shah, J. A.
10.1101/2020.08.24.263624 — immunology — Posted on 2020-11-06
3296 Superior Colliculus to VTA pathway controls orienting response to conspecific stimuli.
Prevost-Solie, C.; Contestaile, A.; Espinosa, P.; Musardo, S.; Bariselli, S.; Huber, C.; Carleton, A.; Bellone, C.
10.1101/735340 — neuroscience — Posted on 2020-11-06
3298 Data-driven classification of spectral profiles reveals brain region-specific plasticity
Lubinus, C.; Orpella, J.; Keitel, A.; Gudi-Mindermann, H.; Engel, A. K.; Roeder, B.; Rimmele, J. M.
10.1101/782979 — neuroscience — Posted on 2020-11-06
3300 Sexually divergent cortical control of affective-autonomic integration
Wallace, T.; Schaeuble, D.; Pace, S. A.; Schackmuth, M. K.; Hentges, S. T.; Chicco, A. J.; Myers, B.
10.1101/2020.09.29.319210 — neuroscience — Posted on 2020-11-06
3301 NOise Reduction with DIstribution Corrected (NORDIC) PCA in dMRI with complex-valued parameter-free locally low-rank processing
Moeller, S.; Pishardy, P. K.; Ramanna, s.; Lenglet, C.; Wu, X.; Dowdle, L.; Yacoub, E.; Ugurbil, K.; Akcakaya, M.
10.1101/2020.08.25.267062 — neuroscience — Posted on 2020-11-06
3303 A longitudinal analysis of puberty-related cortical development
Vijayakumar, N.; Youssef, G.; Allen, N. B.; Anderson, V.; Efron, D.; Hazell, P.; Mundy, L.; Nicholson, J. M.; Patton, G.; Seal, M. L.; Simmons, J. G.; Whittle, S.; Silk, T.
10.1101/2020.11.05.370460 — neuroscience — Posted on 2020-11-06
3305 The APETALA2 transcription factor LsAP2 regulates seed shape in lettuce
Luo, C.; Wang, S.; Ning, K.; Chen, Z.; Wang, Y.; Yang, J.; Qi, M.; Wang, Q.
10.1101/2020.11.05.370684 — plant biology — Posted on 2020-11-06
3306 Complex population structure of the Atlantic puffin revealed by whole genome analyses
Kersten, O.; Star, B.; Leigh, D. M.; Anker-Nilssen, T.; Stroem, H.; Danielsen, J.; Descamps, S.; Erikstad, K. E.; Fitzsimmons, M. G.; Fort, J.; Hansen, E. S.; Harris, M. P.; Irestedt, M.; Kleven, O.; Mallory, M. L.; Jakobsen, K. S.; Boessenkool, S.
10.1101/2020.11.05.351874 — genomics — Posted on 2020-11-06
3308 In vivo proteomic mapping through GFP-directed proximity dependent biotin labelling in zebrafish
Xiong, Z.; Lo, H. P.; McMahon, K.-A.; Martel, N.; Jones, A.; Hill, M. M.; Parton, R. G.; Hall, T. E.
10.1101/2020.11.05.370585 — cell biology — Posted on 2020-11-06
3310 Progesterone specifically dampens disease-associated TH1- and TH17-related immune responses during T cell activation in vitro
Hellberg, S.; Raffetseder, J.; Rundquist, O.; Magnusson, R.; Papapavlou, G.; Jenmalm, M. C.; Ernerudh, J.; Gustafsson, M.
10.1101/2020.11.05.370700 — immunology — Posted on 2020-11-06
3313 EEG frequency tagging reveals neural entrainment to people moving in synchrony
Cracco, E.; Lee, H.; van Belle, G.; Quenon, L.; Haggard, P.; Rossion, B.; Orgs, G.
10.1101/2020.11.06.368118 — neuroscience — Posted on 2020-11-06
3314 Mitochondrial pathway polygenic risk scores are associated with Alzheimer's Disease
Paliwal, D.; McInerney, T. W.; Pa, J.; Swerdlow, R. H.; Easteal, S.; Andrews, S. J.
10.1101/2020.11.06.371286 — neuroscience — Posted on 2020-11-06
3317 NERO: A Biomedical Named-entity (Recognition) Ontology with a Large, Annotated Corpus Reveals Meaningful Associations Through Text Embedding
Wang, K.; Stevens, R.; Alachram, H.; Li, Y.; Soldatova, L.; King, R.; Ananiadou, S.; Li, M.; Christopoulou, F.; Ambite, J. L.; Garg, S.; Hermjakob, U.; Marcu, D.; Sheng, E.; Beissbarth, T.; Wingender, E.; Galstyan, A.; Gao, X.; Chambers, B.; Khomtchouk, B. B.; Evans, J. A.; Rzhetsky, A.
10.1101/2020.11.05.368969 — systems biology — Posted on 2020-11-06
3319 Activating Immune Recognition in Pancreatic Ductal Adenocarcinoma Using Autophagy Inhibition, MEK blockade and CD40 Agonism
Jiang, H.; Courau, T.; Lupin-Jimenez, L.; Borison, J.; Ritchie, A. J.; Mayer, A. T.; Krummel, M. F.; Collisson, E. A.
10.1101/2020.11.05.370569 — cancer biology — Posted on 2020-11-06
3320 ExTaxsI: an exploration tool of biodiversity molecular data
Agostinetto, G.; Sandionigi, A.; Chahed, A.; Brusati, A.; Parladori, E.; Balech, B.; Bruno, A.; Pescini, D.; Casiraghi, M.
10.1101/2020.11.05.369983 — bioinformatics — Posted on 2020-11-06
3321 emiRIT: A text-mining based resource for microRNA information
Roychowdhury, D.; Gupta, S.; Qin, X.; Arighi, C. N.; Vijay-Shanker, K.
10.1101/2020.11.05.370593 — bioinformatics — Posted on 2020-11-06
3322 Modeling CRISPR gene drives for suppression of invasive rodents
Champer, S. E.; Oakes, N.; Sharma, R.; Garcia-Diaz, P.; Champer, J.; Messer, P. W.
10.1101/2020.11.05.369942 — ecology — Posted on 2020-11-06
3323 A Mycobacterium tuberculosis effector protein attacks host innate immunity by acting as an unusual ubiquitinating enzyme
Wang, J.; Ge, P.; Lei, Z.; Qiang, L.; Chai, Q.; Zhang, Y.; Lu, Z.; Zhao, D.; Li, B.; Su, J.; Peng, R.; Pang, Y.; Shi, Y.; Gao, G. F.; Qiu, X.-B.; Liu, C. H.
10.1101/2020.11.05.370551 — microbiology — Posted on 2020-11-06
3324 Arenavirus nucleoprotein localizes to mitochondria
Baggio, F.; Hetzel, U.; Nufer, L.; Kipar, A.; Hepojoki, J. M.
10.1101/2020.11.06.370825 — microbiology — Posted on 2020-11-06
3325 Lipidomic Profiling Reveals an Age-Related Deficiency of Skeletal Muscle Proresolving Mediators that Contributes to Maladaptive Tissue Remodeling
Markworth, J. F.; Brown, L. A.; Lim, E.; Castor-Macias, J. A.; Larouche, J.; Macpherson, P. C. D.; Davis, C.; Aguilar, C. A.; Maddipati, K. R.; Brooks, S. V.
10.1101/2020.11.05.370056 — immunology — Posted on 2020-11-06
3337 A single QTL with large effect is associated with female functional virginity in an asexual parasitoid wasp
Ma, W.-J.; Pannebakker, B. A.; Li, X.; Geuverink, E.; Anvar, S. Y.; Veltsos, P.; Schwander, T.; van de Zande, L.; Beukeboom, L. W.
10.1101/2020.11.05.370544 — evolutionary biology — Posted on 2020-11-06
3338 Causal inference gates corticostriatal learning
Dorfman, H. M.; Tomov, M. S.; Cheung, B.; Clarke, D.; Gershman, S. J.; Hughes, B. L.
10.1101/2020.11.05.369793 — neuroscience — Posted on 2020-11-06
3340 Nodosome inhibition as a novel broad-spectrum antiviral strategy against arboviruses and SARS-CoV-2
Limonta, D.; Dyna-Dagman, L.; Branton, W.; Makio, T.; Wozniak, R. W.; Power, C.; Hobman, T. C.
10.1101/2020.11.05.370767 — microbiology — Posted on 2020-11-06
3341 Potent SARS-CoV-2 neutralizing antibodies selected from a human antibody library constructed decades ago
Qiang, M.; Ma, P.; Li, Y.; Liu, H.; Harding, A.; Min, C.; Liu, L.; Yuan, M.; Ji, Q.; Tao, P.; Shi, X.; Li, Z.; Wang, F.; Zhang, Y.; Wu, N. C.; Lee, C.-C. D.; Zhu, X.; Gilbert-Jaramillo, J.; Saxena, A.; Huang, X.; Wang, H.; James, W.; Dwek, R. A.; Wilson, I. A.; Yang, G.; Lerner, R. A.
10.1101/2020.11.06.370676 — microbiology — Posted on 2020-11-06
3343 Flagellin from Pseudomonas aeruginosa modulates SARS-CoV-2 infectivity in CF airway epithelial cells by increasing TMPRSS2 expression
Ruffin, M.; Bigot, J.; Calmel, C.; Mercier, J.; Pizzorno, A.; Rosa-Calatrava, M.; Corvol, H.; Balloy, V.; Terrier, O.; Guillot, L.
10.1101/2020.08.24.264564 — pathology — Posted on 2020-11-06
3345 Acrylamide Fragment Inhibitors that Induce Unprecedented Conformational Distortions in Enterovirus 71 3C and SARS-CoV-2 Main Protease
Qin, B.; Craven, G. B.; Hou, P.; Lu, X.; Child, E. S.; Morgan, R. M. L.; Armstrong, A.; Mann, D. J.; Cui, S.
10.1101/2020.11.06.370916 — biochemistry — Posted on 2020-11-06
3348 Tissue Level Profiling of SARS-CoV-2 antivirals in mice to predict their effects: comparing Remdesivir's active metabolite GS-441 524 vs. the clinically failed Hydroxychloroquine
Scherf-Clavel, O.; Kaczmarek, E.; Kinzig, M.; Friedl, B.; Feja, M.; Hoehl, R.; Nau, R.; Holzgrabe, U.; Gernert, M.; Richter, F.; Soergel, F.
10.1101/2020.09.16.299537 — systems biology — Posted on 2020-11-06
3350 NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Marques, C.; Unterkircher, T.; Kroon, P.; Izzo, A.; Dramaretska, Y.; Kling, E.; Oldrini, B.; Schnell, O.; Nelander, S.; Wagner, E. F.; Bakiri, L.; Gargiulo, G.; Carro, M. S.; Squatrito, M.
10.1101/834531 — cancer biology — Posted on 2020-11-06
3351 The fluid dynamics of collective vortex structures of plant-animal worms
Fortune, G. T.; Worley, A.; Sendova-Franks, A.; Franks, N.; Leptos, K. C.; Lauga, E.; Goldstein, R. E.
10.1101/2020.11.04.366658 — biophysics — Posted on 2020-11-06
3352 periscope: Sub-Genomic RNA Identification in SARS-CoV-2 Genomic Sequencing Data
Parker, M. D.; Lindsey, B. B.; Leary, S.; Gaudieri, S.; Chopra, A.; Wyles, M.; Angyal, A.; Green, L. R.; Parsons, P.; Tucker, R. M.; Brown, R.; Groves, D.; Johnson, K.; Carrilero, L.; Heffer, J.; Partridge, D.; Evans, C.; Razza, M.; Keeley, A. J.; Smith, N.; Filipe, A. D. S.; Shepherd, J. G.; Davis, C.; Bennett, S.; Kohl, A.; Aranday-Cortes, E.; Tong, L.; Nichols, J.; Thomson, E. C.; The COVID-19 Genomics UK (COG-UK) consortium, ; Wang, D.; Mallal, S.; de Silva, T. I.
10.1101/2020.07.01.181867 — bioinformatics — Posted on 2020-11-06
3353 Epigenetic transgenerational effects on RNAi in Arabidopsis
Hu, Q.; Ailhas, J.; Blevins, T.; Klahre, U.; Vazquez, F.; Mette, M. F.; Meins, F.
10.1101/2020.04.05.026641 — plant biology — Posted on 2020-11-06
3358 SGLT2 inhibition by intraperitoneal dapagliflozin mitigates peritoneal fibrosis and ultrafiltration failure in a mouse model of chronic peritoneal exposure to high-glucose dialysate
Balzer, M. S.; Rong, S.; Nordlohne, J.; Zemtsovski, J. D.; Schmidt, S.; Stapel, B.; Bartosova, M.; von Vietinghoff, S.; Haller, H.; Schmitt, C. P.; Shushakova, N.
10.1101/2020.11.04.366724 — molecular biology — Posted on 2020-11-06
3361 Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer's disease mouse model
Muraoka, S.; Jedrychowski, M. P.; Iwahara, N.; Abdullah, M.; Onos, K. D.; Keezer, K. J.; Hu, J.; Ikezu, S.; Howell, G. R.; Gygi, S. P.; Ikezu, T.
10.1101/2020.11.05.369728 — neuroscience — Posted on 2020-11-06
3362 Gene-corrected Parkinson's disease neurons show the A30P alpha-synuclein point mutation leads to reduced neuronal branching and function
Barbuti, P. A.; Santos, B. F.; Antony, P. M.; Massart, F.; Cruciani, G.; Dording, C. M.; Pavelka, L.; Kwon, Y.-J.; Krueger, R. A.
10.1101/2020.11.05.369389 — neuroscience — Posted on 2020-11-06
3364 Sexual selection drives maladaptive learning under climate warming
Holveck, M.-J.; Muller, D.; Visser, B.; Pels, C.; Timmermans, A.; Colonval, L.; Jan, F.; Crucifix, M.; Nieberding, C.
10.1101/2020.11.05.369561 — evolutionary biology — Posted on 2020-11-06
3369 Single-cell RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates and humans
Bakken, T. E.; van Velthoven, C. T. J.; Menon, V.; Hodge, R. D.; Yao, Z.; Nguyen, T. N.; Graybuck, L. T.; Horwitz, G. D.; Bertagnolli, D.; Goldy, J.; Garren, E.; Parry, S.; Casper, T.; Shehata, S. I.; Barkan, E. R.; Szafer, A.; Levi, B. P.; Dee, N.; Smith, K. A.; Sunkin, S. M.; Bernard, A.; Phillips, J. W.; Hawrylycz, M.; Koch, C.; Murphy, G.; Lein, E.; Zeng, H.; Tasic, B.
10.1101/2020.11.05.367482 — neuroscience — Posted on 2020-11-06
3370 Breaking the limit of 3D fluorescence microscopy by dual-stage-processing network
Zhang, H.; Zhao, Y.; Fang, C.; Li, G.; Zhang, M.; Zhang, Y.; Fei, P.
10.1101/435040 — biophysics — Posted on 2020-11-06
3374 Mass spectrometry and CLIP-seq analysis reveal BCL11b interactions with RNA processing pathways
Sobhy, H.; De Rovere, M.; Ait-Ammar, A.; WALLET, C.; DAOUAD, F.; Van Lint, C.; SCHWARTZ, C.; ROHR, O.
10.1101/2020.11.05.369959 — developmental biology — Posted on 2020-11-06
3377 Ultra-precise quantification of mRNA targets across a broad dynamic range with nanoreactor beads
Loncarevic, I. F.; Toepfer, S.; Hubold, S.; Klingner, S.; Kanitz, L.; Ellinger, T.; Steinmetzer, K.; Ernst, T.; Hochhaus, A.; Ermantraut, E.
10.1101/2020.11.05.369637 — molecular biology — Posted on 2020-11-05
3378 Innate fear responses are reflected in the blood epigenome of rhesus macaques.
Bravo-Rivera, H.; Lardenoije, R.; Merced, D.; Mas-Rivera, A.; Ayala, J. E.; Goncalves, J. P.; Seligowski, A. V.; Jovanovic, T.; Ressler, K. J.; Klengel, T.; Quirk, G. J.
10.1101/2020.11.05.369538 — neuroscience — Posted on 2020-11-05
3379 AMPK Modulates Associative Learning via Neuronal Mitochondrial Fusion in C. elegans
Escoubas, C. C.; Laversenne, V.; Tabakovic, E.; Weir, H. J.; Clark, N.; Mair, W. B.
10.1101/2020.11.05.370031 — neuroscience — Posted on 2020-11-05
3381 Lipidation of a bacterial effector is critical for bacterial evasion of host-defense
Cattelan, N.; Yu, H.; Przybyszewska, K.; Colamarino, R. A.; Baldassarre, M.; Spano, S.
10.1101/2020.11.05.369652 — microbiology — Posted on 2020-11-05
3383 Synergy and allostery in ligand binding by HIV-1 Nef
Aldehaiman, A.; Momin, A. A.; Restouin, A.; Wang, L.; Shi, X.; Aljedani, S.; Opi, S.; Lugari, A.; Hameed, U. F. S.; Ponchon, L.; Morelli, X.; Huang, M.; Dumas, C.; Collette, Y.; Arold, S. T.
10.1101/2020.11.05.369645 — biophysics — Posted on 2020-11-05
3386 CRISPRIdentify: Identification of CRISPR arrays using machine learning approach
Mitrofanov, A.; Alkhnbashi, O. S.; Shmakov, S. A.; Makarova, K. S.; Koonin, E. V.; Backofen, R.
10.1101/2020.11.05.369512 — bioinformatics — Posted on 2020-11-05
3387 A new duck genome reveals conserved and convergently evolved chromosome architectures of birds and mammals
Li, J.; Zhang, J.; Liu, J.; Zhou, Y.; Cai, C.; Xu, L.; Dai, X.; Feng, S.; Guo, C.; Rao, J.; Wei, K.; Jarvis, E.; Jiang, Y.; Zhou, Z.; Zhang, G.; Zhou, Q.
10.1101/2020.11.04.368910 — genomics — Posted on 2020-11-05
3388 The recombination landscape and multiple QTL mapping in a Solanum tuberosum cv. 'Atlantic'-derived F1 population
Da Silva Pereira, G.; Mollinari, M.; Schumann, M. J.; Clough, M. E.; Zeng, Z.-B.; Yencho, C.
10.1101/2020.08.24.265397 — genetics — Posted on 2020-11-05
3391 Bromodomain protein inhibition protects β-cells from cytokine-induced death and dysfunction via antagonism of NF-κB pathway.
Negi, V.; Lee, J.; Liu, R.; Perez-Garcia, E. M.; Li, F.; Jagannathan, R.; Yang, P.; Bottino, R.; Ma, K.; Moulik, M.; Yechoor, V.
10.1101/2020.11.05.363408 — molecular biology — Posted on 2020-11-05
3392 AXTEX-4D™: A Novel 3D ex vivo platform for preclinical investigations of immunotherapy agents
Baru, A.; Sharma, S.; Das Purkayastha, B. P.; Khan, S.; Mazumder, S.; Gupta, R.; Kundu, P. K.; Arora, N. M.
10.1101/2020.11.05.369751 — immunology — Posted on 2020-11-05
3394 The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal cord injury in male mice
Toro, C. A.; Hansen, J.; Siddiq, M. M.; Johnson, K.; Zhao, W.; Azulai, D.; Das, D. K.; Bauman, W.; Sebra, R.; Cai, D.; Iyengar, R.; Cardozo, C. P.
10.1101/2020.11.05.369900 — neuroscience — Posted on 2020-11-05
3397 Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine-learning toolbox
Wirbel, J.; Zych, K.; Essex, M.; Karcher, N.; Kartal, E.; Salazar, G.; Bork, P.; Sunagawa, S.; Zeller, G.
10.1101/2020.02.06.931808 — bioinformatics — Posted on 2020-11-05
3399 iPSC culture expansion selects against putatively actionable mutations in the mitochondrial genome
Kosanke, M.; Davenport, C.; Szepes, M.; Wiehlmann, L.; Kohrn, T.; Dorda, M.; Gruber, J.; Menge, K.; Sievert, M.; Melchert, A.; Gruh, I.; Martin, U.
10.1101/2020.11.05.369694 — genomics — Posted on 2020-11-05
3401 Ecological dynamics of the almond floral microbiome in relation to crop management and pollination
Schaeffer, R. N.; Crowder, D. W.; Illan, J. G.; Beck, J. J.; Fukami, T.; Williams, N. M.; Vannette, R. L.
10.1101/2020.11.05.367003 — ecology — Posted on 2020-11-05
3402 Prevalence of sustainable and unsustainable use of wild species inferred from the IUCN Red List
Marsh, S. M. E.; Hoffmann, M.; Burgess, N. D.; Brooks, T. M.; Challender, D. W. S.; Cremona, P. J.; Hilton-Taylor, C.; Lafaye de Micheaux, F.; Lichtenstein, G.; Roe, D.; Bohm, M.
10.1101/2020.11.04.367763 — ecology — Posted on 2020-11-05
3403 Mass spectrometry and CLIP-seq analysis reveal BCL11b interactions with RNA processing pathways
Sobhy, H.; De Rovere, M.; Ait-Ammar, A.; SCHWARTZ, C.; Van Lint, C.; ROHR, O.; WALLET, C.; DAOUAD, F.
10.1101/2020.11.05.369959 — developmental biology — Posted on 2020-11-05
3404 Liver FoxO1 overexpression is positively associated with the degree of liver injury in cirrhotic patients
Fernandez-Galan, E.; Sandalinas, S.; Morales-Romero, B.; Macias, L.; Pauta, M.; Ribera, J.; Casals, G.; Boix, L.; Bruix, J.; Jimenez, W.; Morales-Ruiz, M.
10.1101/2020.11.05.369504 — cell biology — Posted on 2020-11-05
3406 Metabolomic investigation of the pseudouridimycin producer, a prolific streptomycete
Iorio, M.; Davatgarbenam, S.; Serina, S.; Criscenzo, P.; Zdouc, M. M.; Simone, M.; Maffioli, S. I.; Ebright, R. H.; Donadio, S.; Sosio, M.
10.1101/2020.11.05.369249 — microbiology — Posted on 2020-11-05
3408 SLAMF7 engagement super-activates macrophages in acute and chronic inflammation
Simmons, D. P.; Nguyen, H.; Gomez-Rivas, E.; Jeong, Y.; Chen, A. F.; Lange, J. K.; Dyer, G. S.; Blazar, P.; Earp, B. E.; RA/SLE Network, A. M. P.; Rao, D. A.; Kim, E. Y.; Brenner, M. B.
10.1101/2020.11.05.368647 — immunology — Posted on 2020-11-05
3412 HERC1 regulates breast cancer cells migration and invasion
Rossi, F. A.; Calvo Roitberg, E. H.; Enrique Steinberg, J. H.; Joshi, M.; Espinosa, J. M.; Rossi, M.
10.1101/2020.11.05.369975 — cancer biology — Posted on 2020-11-05
3414 Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
Belan, O.; Barroso, C.; Kaczmarczyk, A.; Anand, R.; Federico, S.; O'Reilly, N.; Newton, M. D.; Maeots, E.; Enchev, R. I.; Martinez-Perez, E.; Rueda, D. S.; Boulton, S. J.
10.1101/2020.11.05.369629 — biophysics — Posted on 2020-11-05
3417 RatsPub: a webservice aided by deep learning to mine PubMed for addiction-related genes
Gunturkun, M. H.; Flashner, E.; Wang, T.; Mulligan, M. K.; Williams, R. W.; Prins, P.; Chen, H.
10.1101/2020.09.17.297358 — bioinformatics — Posted on 2020-11-05
3420 Complete and haplotype-specific sequence assembly of segmental duplication-mediated genome rearrangements using CRISPR-targeted ultra-long read sequencing (CTLR-Seq)
Zhou, B.; Shin, G.; Greer, S. U.; Vervoort, L.; Huang, Y.; Pattni, R.; Ho, M.; Wong, W. H.; Vermeesch, J. R.; Ji, H.; Urban, A. E.
10.1101/2020.10.23.349621 — genomics — Posted on 2020-11-05
3424 Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
Tzani, I.; Herrmann, N.; Carillo, S.; Spargo, C. A.; Hagan, R.; Barron, N.; Bones, J.; Dilmore, W. S.; Clarke, C.
10.1101/2020.11.04.368480 — cell biology — Posted on 2020-11-05
3428 Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Wang, L.; Astone, M.; Alam, S. K.; Zhu, Z.; Pei, W.; Frank, D. A.; Burgess, S. M.; Hoeppner, L. H.
10.1101/2020.10.27.358374 — molecular biology — Posted on 2020-11-05
3430 SARS-CoV-2 Assembly and Egress Pathway Revealed by Correlative Multi-modal Multi-scale Cryo-imaging
Mendonca, L.; Howe, A.; Gilchrist, J. B.; Sun, D.; Knight, M.; Zanetti-Domingues, L. C.; Bateman, B.; Krebs, A.-S.; Chen, L.; Radecke, J.; Sheng, Y.; Li, V. D.; Ni, T.; Kounatidis, I.; Koronfel, M. A.; Szynkiewicz, M.; Harkiolaki, M.; Martin-Fernandez, M. L.; James, W.; Zhang, P.
10.1101/2020.11.05.370239 — microbiology — Posted on 2020-11-05
3431 Immunocompetent Mouse Model for Crimean-Congo Hemorrhagic Fever Virus
Hawman, D. W.; Meade-White, K.; Leventhal, S.; Feldmann, F.; Okumura, A.; Smith, B.; Scott, D.; Feldmann, H.
10.1101/2020.11.05.369520 — immunology — Posted on 2020-11-05
3434 Cryo-EM structure of a proton-activated chloride channel TMEM206
Deng, Z.; Zhao, Y.; Feng, J.; Zhang, J.; Zhao, H.; Rau, M. J.; Fitzpatrick, J.; Hu, H.; Yuan, P.
10.1101/2020.11.05.369835 — biophysics — Posted on 2020-11-05
3437 A Fast Lysine Cross-linker DOPA Enables Mass Spectrometry Analyses of Protein Unfolding and Weak Protein-protein Interactions
Wang, J.-H.; Tang, Y.-L.; Jain, R.; Xiao, F.; Gong, Z.; Zhou, Y.; Tan, D.; Li, Q.; Dong, X.; Liu, S.-Q.; Tang, C.; Huang, N.; Ye, K.; Dong, M.-Q.; Lei, X.
10.1101/2020.11.05.369280 — biochemistry — Posted on 2020-11-05
3438 Identification of blood autosomal cis-expression quantitative trait methylation (cis-eQTMs) in children
Ruiz-Arenas, C.; Hernandez-Ferrer, C.; Vives-Usano, M.; Mari, S.; Quintela, I.; Mason, D.; Cadiou, S.; Casas, M.; Andrusaityte, S.; Gutzkow, K. B.; Vafeiadi, M.; Wright, J.; Lepeule, J.; Grazuleviciene, R.; Chatzi, L.; Carracedo, a.; Estivill, X.; Marti, E.; Escaramis, G.; Vrijheid, M.; Gonzalez, J. R.; Bustamante, M.
10.1101/2020.11.05.368076 — genomics — Posted on 2020-11-05
3443 Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior
Cherix, A.; Poitry-Yamate, C.; Lanz, B.; Zanoletti, O.; Grosse, J.; Sandi, C.; Gruetter, R.; Cardinaux, J.-R.
10.1101/2020.11.05.370221 — neuroscience — Posted on 2020-11-05
3444 Non-lesioned subcortical brain volumes are associated with post-stroke sensorimotor behavior across 28 cohorts worldwide: An ENIGMA Stroke Recovery study
Liew, S.-L.; Zavaliangos-Petropulu, A.; Schweighofer, N.; Jahanshad, N.; Lang, C. E.; Lohse, K. R.; Banaj, N.; Barisano, G.; Baugh, L. A.; Bhattacharya, A. K.; Bigjahan, B.; Borich, M. R.; Boyd, L. A.; Brodtmann, A.; Buetefisch, C. M.; Byblow, W. D.; Cassidy, J. M.; Ciullo, V.; Conforto, A. B.; Craddock, R. C.; Dula, A. N.; Egorova, N.; Feng, W.; Fercho, K. A.; Gregory, C. M.; Hanlon, C. A.; Hayward, K. S.; Holguin, J. A.; Hordacre, B.; Hwang, D. H.; Kautz, S. A.; Khlif, M. S.; Kim, B.; Kuceyeski, A.; Liu, J.; Lin, D.; Lotze, M.; Kim, H.; MacIntosh, B. J.; Margetis, J. L.; Mohamed, F. B.; Nord
10.1101/2020.11.04.366856 — neuroscience — Posted on 2020-11-05
3447 Interrogation of SLFN11 in pediatric sarcomas uncovers an unexpected biological role and a novel therapeutic approach to overcoming resistance to replicative stress
Gartrell, J.; Mellado-Lagarde, M.; Martinez, N.; Clay, M.; Bahrami, A.; Sahr, N.; Sykes, A.; Blankenship, K.; Hoffmann, L.; Xie, J.; Cho, H. P.; Twarog, N.; Connelly, M.; Yan, K.-K.; Yu, J.; Porter, S. N.; Pruett-Miller, S. M.; Neale, G.; Tinkle, C.; Federico, S.; Stewart, E.; Shelat, A.
10.1101/2020.11.05.370155 — cancer biology — Posted on 2020-11-05
3448 Mechanistic inferences from analysis of measurements of protein phase transitions in live cells
Posey, A. E.; Ruff, K. M.; Lalmansingh, J. M.; Kandola, T. S.; Lange, J. J.; Halfmann, R.; Pappu, R. V.
10.1101/2020.11.04.369017 — biophysics — Posted on 2020-11-05
3449 The fluid dynamics of collective vortex structures of plant-animal worms
Fortune, G. T.; Worley, A.; Sendova-Franks, A.; Franks, N.; Leptos, K. C.; Goldstein, R. E.
10.1101/2020.11.04.366658 — biophysics — Posted on 2020-11-05
3451 Microbiome data enhances predictive models of lung function in people with cystic fibrosis
Zhao, C. Y.; Hao, Y.; Wang, Y.; Varga, J. J.; Stecenko, A. A.; Goldberg, J. B.; Brown, S. P.
10.1101/656066 — bioinformatics — Posted on 2020-11-05
3452 Integrated Analysis of Cell Shape and Movement in Moving Frame
Heryanto, Y. D.; Cheng, C.-Y.; Uchida, Y.; Mimura, K.; Ishii, M.; Yamada, R.
10.1101/2020.11.04.369033 — bioinformatics — Posted on 2020-11-05
3456 Age and diet shape the genetic architecture of body weight in Diversity Outbred mice
Wright, K. M.; Deighan, A.; Francesco, A. D.; Freund, A.; Jojic, V.; Churchill, G. A.; Raj, A.
10.1101/2020.11.04.364398 — genetics — Posted on 2020-11-05
3458 Streamlined and quantitative detection of chimerism in mouse tissue using digital PCR
Suchy, F. P.; Nishimura, T.; Wilkinson, A. C.; Higuchi, M.; Bhadury, J.; Nakauchi, H.
10.1101/2020.11.04.368944 — genetics — Posted on 2020-11-05
3459 Obligate cross-feeding expands the metabolic niche of bacteria
Ona, L.; Giri, S.; Avermann, N.; Kreienbaum, M.; Thormann, K.; Kost, C.
10.1101/2020.11.04.368415 — evolutionary biology — Posted on 2020-11-05
3462 Transcription and splicing dynamics during early Drosophila development
Prudencio, P.; Rebelo, K.; Savisaar, R.; Martinho, R. G.; Carmo-Fonseca, M.
10.1101/2020.11.05.367888 — molecular biology — Posted on 2020-11-05
3465 High fidelity electrophysiological, morphological, and transcriptomic cell characterization using a refined Patch-seq protocol
Lee, B. R.; Budzillo, A.; Hadley, K.; Miller, J. A.; Jarsky, T.; Baker, K.; Hill, D.; Kim, L.; Mann, R.; Ng, L.; Oldre, A.; Rajanbabu, R.; Trinh, J.; Braun, T.; Dalley, R.; Gouwens, N. W.; Kim, T. K.; Smith, K.; Soler-Llavina, G.; Sorensen, S.; Tasic, B.; Ting, J. T.; Zeng, H.; Murphy, G.; Berg, J.
10.1101/2020.11.04.369082 — neuroscience — Posted on 2020-11-05
3467 Landmark-Centered Coding in Frontal Cortex Visual Responses
Schuetz, A.; Bharmauria, V.; Yan, X.; Wang, H.; Bremmer, F.; Crawford, J. D.
10.1101/2020.11.04.368308 — neuroscience — Posted on 2020-11-05
3468 A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
Vizioli, L.; Moeller, S.; Dowdle, L.; Akcakaya, M.; De Martino, F.; Yacoub, E.; Ugurbil, K.
10.1101/2020.11.04.368357 — neuroscience — Posted on 2020-11-05
3471 Numerical Instabilities in Analytical Pipelines Lead to Large and Meaningful Variability in Brain Networks
Kiar, G.; Chatelain, Y.; de Oliveira Castro, P.; Petit, E.; Rokem, A.; Varoquaux, G.; Misic, B.; Evans, A. C.; Glatard, T.
10.1101/2020.10.15.341495 — neuroscience — Posted on 2020-11-05
3476 Performance of deep learning restoration methods for the extraction of particle dynamics in noisy microscopy image sequences
Kefer, P.; Iqbal, F.; Locatelli, M.; Lawrimor, J.; Zhang, M.; Bloom, K.; Bonin, K.; Vidi, P.-A.; Liu, J.
10.1101/2020.11.04.368928 — biophysics — Posted on 2020-11-05
3483 Scaling up biodiversity ecosystem functioning relationships: the role of environmental variability in space and time
Thompson, P. L.; Kefi, S.; Zelnik, Y. R.; Dee, L. E.; Wang, S.; de Mazancourt, C.; Loreau, M.; Gonzalez, A.
10.1101/2020.11.04.367250 — ecology — Posted on 2020-11-05
3486 Cytokinin inhibits fungal development and virulence by targeting cellular trafficking
Gupta, R.; Pizarro, L.; Anand, G.; Laor, D.; Kovetz, N.; Yehuda, T.; Gazit, E.; Bar, M.
10.1101/2020.11.04.369215 — microbiology — Posted on 2020-11-05
3488 Aberrant peripheral immune responses in acute Kawasaki disease with single-cell sequencing
Wang, Z.; Xie, L.; Song, S.; Chen, L.; Li, G.; Liu, J.; Xiao, T.; Zhang, H.; Huang, Y.; Ding, G.; Li, Y.; Huang, M.
10.1101/2020.11.05.369348 — immunology — Posted on 2020-11-05
3489 Synchronous and opponent thermosensors use flexible cross-inhibition to orchestrate thermal homeostasis
Hernandez-Nunez, L.; Chen, A.; Budelli, G.; Richter, V.; Rist, A.; Thum, A. S.; Klein, M.; Garrity, P. A.; Samuel, A. D. T.
10.1101/2020.07.09.196428 — neuroscience — Posted on 2020-11-05
3492 Tracking tau fibrillogenesis and consequent primary phagocytosis of neurons mediated by microglia in a living tauopathy model
Takuwa, H.; Orihara, A.; Takado, Y.; Shimojo, M.; Ishikawa, A.; Takahash, M.; Barron, A. M.; Ono, M.; Maeda, J.; Masamoto, K.; Akatsu, H.; Tolkovsky, A. M.; Ji, B.; Tomita, Y.; Ito, H.; Zhang, M.-R.; Goedert, M.; Spillantini, M. G.; Lee, V. M.-Y.; Trojanowski, J. Q.; Maehara, T.; Suhara, T.; Sahara, N.; Higuchi, M.
10.1101/2020.11.04.368977 — neuroscience — Posted on 2020-11-05
3495 Challenges in Undergraduate Synthetic Biology Training: Insights from a Canadian iGEM Student Perspective
Diep, P.; Boucinha, A.; Yeung, B.-r. A.; Kell, B.; Chen, X.; Tsyplenkov, D.; Serra, D.; Escobar, A.; Gnanapragasam, A.; Emond, C. A.; Sajtovich, V. A.; Mahadevan, R.; Kilkenny, D. M.; Gini-Newman, G.; Kaern, M.; Ingalls, B.
10.1101/2020.11.04.365999 — scientific communication and education — Posted on 2020-11-05
3496 Regulation of touch dependant de novo root regeneration in Arabidopsis
Shanmukhan, A. P.; Mathew, M. M.; Aiyaz, M.; Kareem, A.; Radhakrishnan, D.; Prasad, K.
10.1101/2020.11.04.367714 — plant biology — Posted on 2020-11-05
3498 Structural insights on the substrate-binding proteins of the Mycobacterium tuberculosis mammalian-cell-entry (Mce) 1 and 4 complexes
Asthana, P.; Singh, D.; Pedersen, J. S.; Hynönen, M. J.; Sulu, R.; Murthy, A. V.; Laitaoja, M.; Jänis, J.; W. Riley, L.; Venkatesan, R.
10.1101/2020.09.29.317909 — biophysics — Posted on 2020-11-05
3501 Phosphonate production by marine microbes: exploring new sources and potential function
Acker, M.; Hogle, S. L.; Berube, P. M.; Hackl, T.; Stepanauskas, R. M.; Chisholm, S. W.; Repeta, D. J.
10.1101/2020.11.04.368217 — biochemistry — Posted on 2020-11-05
3502 Revealing the evolutionary history of a reticulate polyploid complex in the genus Isoëtes
Suissa, J. S.; Kinosian, S. P.; Schafran, P. W.; Bolin, J. F.; Taylor, W. C.; Zimmer, E.
10.1101/2020.11.04.363374 — evolutionary biology — Posted on 2020-11-05
3504 High-throughput CRISPR screens to dissect macrophage-Shigella interactions
Lai, Y.; Cui, L.; Babunovic, G. H.; Fortune, S. M.; Doench, J. G.; Lu, T. K.
10.1101/2020.04.25.061671 — microbiology — Posted on 2020-11-05
3505 Hippocampal subfields integrate information about past temporal and cognitive contexts
Dimsdale-Zucker, H. R.; Montchal, M. E.; Reagh, Z. M.; Wang, S.-F.; Libby, L. A.; Ranganath, C. R.
10.1101/766311 — neuroscience — Posted on 2020-11-05
3507 Robust Inference of Kinase Activity using Functional Networks
Yilmaz, S.; Ayati, M.; Schlatzer, D.; Cicek, A. E.; Chance, M.; Koyuturk, M.
10.1101/2020.05.01.062802 — systems biology — Posted on 2020-11-05
3509 Chromatin-accessibility estimation of single-cell ATAC data
Li, Z.; Kuppe, C.; Ziegler, S.; Cheng, M.; Kabgani, N.; Menzel, S.; Zenke, M.; Kramann, R.; Costa, I. G.
10.1101/865931 — bioinformatics — Posted on 2020-11-05
3510 Rapid High Throughput Whole Genome Sequencing of SARS-CoV-2 by using One-step RT-PCR Amplification with Integrated Microfluidic System and Next-Gen Sequencing
Hang, J.; Li, T.; Chung, H. K.; Pireku, P. K.; Beitzel, B.; Sanborn, M. A.; Tang, C.; Hammer, R.; Ritter, D. G.; Wan, X.-F.; Maljkovic Berry, I.
10.1101/2020.11.04.369165 — molecular biology — Posted on 2020-11-05
3511 Human Identical Sequences of SARS-CoV-2 Promote Clinical Progression of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer Network
Li, W.; Yang, S.; Xu, P.; Zhang, D.; Tong, Y.; Chen, L.; Jia, B.; Li, A.; Ru, D.; Zhang, B.; Liu, M.; Lian, C.; Chen, C.; Fu, W.; Yuan, S.; Ren, X.; Liang, Y.; Yang, Z.; Li, W.; Wang, S.; Zhang, X.; Lu, H.; Xu, J.; Wang, H.; Yu, W.
10.1101/2020.11.04.361576 — molecular biology — Posted on 2020-11-05
3512 The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity
Thomson, E. C.; Rosen, L. E.; Shepherd, J. G.; Spreafico, R.; da Silva Filipe, A.; Wojcechowskyj, J. A.; Davis, C.; Piccoli, L.; Pascall, D. J.; Dillen, J.; Lytras, S.; Czudnochowski, N.; Shah, R.; Meury, M.; Jesudason, N.; De Marco, A.; Li, K.; Bassi, J.; O'Toole, A.; Pinto, D.; Colquhoun, R. M.; Culap, K.; Jackson, B.; Zatta, F.; Rambaut, A.; Jaconi, S.; Sreenu, V. B.; Nix, J.; Jarrett, R. F.; Beltramello, M.; Nomikou, K.; Pizzuto, M.; Tong, L.; Cameroni, E.; Johnson, N.; Wickenhagen, A.; Ceschi, A.; Mair, D.; Ferrari, P.; Smollett, K.; Sallusto, F.; Carmichael, S.; Garzoni, C.; Nichols, J.;
10.1101/2020.11.04.355842 — microbiology — Posted on 2020-11-05
3513 Comparison of SARS-CoV-2 infection in two non-human primate species: rhesus and cynomolgus macaques
Boszormenyi, K. P.; Stammes, M. A.; Fagrouch, Z. C.; Kiemenyi-Kayere, G.; Niphuis, H.; Mortier, D.; van Driel, N.; Nieuwenhuis, I.; Zuiderwijk-Sick, E.; Meijer, L.; Mooij, P.; Remarque, E. J.; Koopman, G.; Hoste, A. C. R.; Sastre, P.; Haagmans, B. L.; Bontrop, R. E.; Langermans, J. A. M.; Bogers, W. M.; Verschoor, E. J.; Verstrepen, B. E.
10.1101/2020.11.05.369413 — microbiology — Posted on 2020-11-05
3514 The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN
Soh, W. T.; Liu, Y.; Nakayama, E. E.; Ono, C.; Torii, S.; Nakagami, H.; Matsuura, Y.; Shioda, T.; Arase, H.
10.1101/2020.11.05.369264 — microbiology — Posted on 2020-11-05
3515 A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research
Zahoranszky-Kohalmi, G.; Siramshetty, V. B.; Kumar, P.; Gurumurthy, M.; Grillo, B.; Mathew, B.; Metaxatos, D.; Backus, M.; Mierzwa, T.; Simon, R.; Grishagin, I.; Brovold, L.; Mathe, E. A.; Hall, M. D.; Michael, S. G.; Godfrey, A. G.; Mestres, J.; Jensen, L. J.; Oprea, T. I.
10.1101/2020.11.04.369041 — systems biology — Posted on 2020-11-05
3516 The Establishment of Transgenerational Epigenetic Inheritance in the C. elegans Germline is Mediated by Lipid Metabolism
Dan, P.; Chen, W.; Kai-Le, L.; Zhi-Xue, G.; Yong-Hao, L.; Hao-Wei, W.; Qiu-Yu, L.; Xi-Wei, L.; He-Yuan, S.; Yuan-Ya, J.; Qiang, F.; Qian, Z.; Lei, Z.; Huan-Huan, C.; Huan-Yin, T.; Xiao-Mei, Y.; Jian-Feng, C.; Feng, S.; Wei, L.; Fang-Lin, S.
10.1101/2020.11.04.367854 — genetics — Posted on 2020-11-05
3517 From local spectral species to global spectral communities: a benchmark for ecosystem diversity estimate by remote sensing
Rocchini, D.; Salvatori, N.; Beierkuhnlein, C.; Chiarucci, A.; de Boissieu, F.; Foerster, M.; Garzon-Lopez, C. X.; Gillespie, T. W.; Hauffe, H. C.; He, K. S.; Kleinschmit, B.; Lenoir, J.; Malavasi, M.; Moudry, V.; Nagendra, H.; Payne, D.; Simova, P.; Torresani, M.; Wegmann, M.; Feret, J.-B.
10.1101/2020.11.04.367995 — ecology — Posted on 2020-11-05
3518 Extending the integrate-and-fire model to account for metabolic dependencies
Jaras, I.; Harada, T.; Orchard, M. E.; Maldonado, P. E.; Vergara, R. C.
10.1101/2020.11.04.367102 — neuroscience — Posted on 2020-11-05
3519 Localized Chemogenetic Silencing of Inhibitory Neurons: A novel Mouse Model of Focal Cortical Seizures
Goldenberg, A. M.; Schmidt, S.; Mitelman, R.; Rubi Levy, D.; Katz, Y.; Yizhar, O.; Beck, H.; Lampl, I.
10.1101/2020.11.04.367862 — neuroscience — Posted on 2020-11-05
3522 Single-cell Multi-omics reveal heterogeneity and metastasis potential in different liver cancer cell lines
Wu, L.; Xie, J.; Wang, S.; Zou, X.; Pan, T.; Zhuang, Z.; Wang, Z.; Yuan, Y.; Liu, L.; Liu, S.
10.1101/2020.11.03.367532 — cancer biology — Posted on 2020-11-05
3525 Novel imprints in mouse blastocysts are predominantly DNA methylation independent
Santini, L.; Halbritter, F.; Titz-Teixeira, F.; Suzuki, T.; Asami, M.; Ramesmayer, J.; Ma, X.; Lackner, A.; Warr, N.; Pauler, F.; Hippenmeyer, S.; Laue, E.; Farlik, M.; Bock, C.; Beyer, A.; Perry, A. C. F.; Leeb, M.
10.1101/2020.11.03.366948 — genomics — Posted on 2020-11-05
3526 Automated AI labelling of optic nerve head enables new insights into cross-ancestry glaucoma risk and genetic discovery in over 280,000 images from the UK Biobank and Canadian Longitudinal Study on Aging
Han, X.; Steven, K.; Qassim, A.; Marshall, H. N.; Bean, C.; Tremeer, M.; An, J.; Siggs, O.; Gharahkhani, P.; Craig, J. E.; Hewitt, A. W.; Trzaskowski, M.; MacGregor, S.
10.1101/2020.11.03.367623 — genetics — Posted on 2020-11-05
3529 Prevalence of sustainable and unsustainable use of wild species inferred from the IUCN Red List
Marsh, S. M. E.; Hoffmann, M.; Burgess, N. D.; Brooks, T. M.; Challender, D. W. S.; Cremona, P. J.; Hilton-Taylor, C.; Lafaye de Micheaux, F.; Lichtenstein, G.; Bohm, M.; Roe, D.
10.1101/2020.11.04.367763 — ecology — Posted on 2020-11-05
3531 Intracellular sterol sensing controls intestinal B cell differentiation
Trindade, B. C.; Ceglia, S.; Berthelette, A.; Raso, F.; Howley, K.; Muppidi, J. R.; Reboldi, A.
10.1101/2020.11.03.367177 — immunology — Posted on 2020-11-05
3533 MiniFAST: A sensitive and fast miniaturized microscope for in vivo neural recording
Juneau, J.; Duret, G.; Chu, J.; Rodriguez, A.; Morozov, S.; Aharoni, D.; Robinson, J.; St-Pierre, F.; Kemere, C.
10.1101/2020.11.03.367466 — neuroscience — Posted on 2020-11-05
3535 Vascular cognitive impairment in the mouse reshapes visual, spatial network functional connectivity.
Hall, G. R.; Boehm-Sturm, P.; Dirnagl, U.; Finke, C.; Foddis, M.; Harms, C.; Koch, S. P.; Kuchling, J.; Madan, C. R.; Mueller, S.; Sassi, C.; Sotiropoulos, S.; Trueman, R. C.; Wallis, M.; Yildirim, F. R.; Farr, T. D.
10.1101/2020.11.04.366294 — neuroscience — Posted on 2020-11-05
3537 Pumiliotoxin metabolism and molecular physiology in a poison frog
Alvarez-Buylla, A.; Payne, C. Y.; Vidoudez, C.; Trauger, S. A.; O'Connell, L. A.
10.1101/2020.11.03.367524 — physiology — Posted on 2020-11-05
3542 Genetic evidence for bidirectional causal effects between resilience and well-being.
de Vries, L. P.; Baselmans, B. M. L.; Luykx, J.; de Zeeuw, E. L.; Minica, C.; de Geus, E. J. C.; Vinkers, C. H.; Bartels, M.
10.1101/2020.11.03.366492 — genetics — Posted on 2020-11-05
3544 No leading-edge effect in North Atlantic harbor porpoises: Evolutionary and conservation implications
Ben Chehida, Y.; Loughnane, R.; Thumloup, J.; Kaschner, K.; Garilao, C.; Rosel, P. E.; Fontaine, M. C.
10.1101/2020.11.03.366542 — evolutionary biology — Posted on 2020-11-05
3547 New water and air pollution sensors added to the Sonic Kayak citizen science system for low cost environmental mapping
Griffiths, A.; Garrett, J. K.; Duffy, J. P.; Matthews, K.; Visi, F. G.; Eatock, C.; Robinson, M.; Griffiths, D. J.
10.1101/2020.11.03.366229 — ecology — Posted on 2020-11-05
3550 Environmental DNA for tracking waterhole visitation in savanna ecosystems
Farrell, M. J.; Govender, D.; Hajibabaei, M.; van der Bank, M.; Davies, T. J.
10.1101/2020.11.03.367417 — ecology — Posted on 2020-11-05
3553 Photoperiod Sensitive Energy Sorghum Responses to Environmental and Nitrogen Variabilities
Schetter, A. A.; Lin, C.-H.; Zumpf, C.; Jang, C.; Hoffmann, L.; Rooney, W. L.; Lee, D. K.
10.1101/2020.11.03.366898 — plant biology — Posted on 2020-11-05
3554 The epithelial-mesenchymal transcription factor SNAI1 represses transcription of the tumor suppressor miRNA let-7 in cancer
Wang, H.; Chirshev, E.; Hojo, N.; Suzuki, T.; Bertucci, A.; Pierce, M.; Perry, C.; Wang, R.; Zink, J. I.; Glackin, C.; Ioffe, Y.; Unternaehrer, J.
10.1101/2020.11.04.368688 — cancer biology — Posted on 2020-11-05
3555 Contrast-enhanced sonography with biomimetic lung surfactant nanodrops
Thomas, A.; Song, K.-H.; Upadhyay, A.; Papadopoulou, V.; Ramirez, D.; Beninger, R.; Lowerison, M.; Song, P.; Murray, T.; Borden, M. A.
10.1101/2020.11.03.367235 — bioengineering — Posted on 2020-11-05
3556 Olfactory rod cells: a rare cell type in the larval zebrafish olfactory epithelium with an actin-rich apical projection
Cheung, K. Y.; Jesuthasan, S. J.; Baxendale, S.; van Hateren, N. J.; Marzo, M.; Hill, C. J.; Whitfield, T. T.
10.1101/2020.11.04.367979 — developmental biology — Posted on 2020-11-05
3558 Poised cell circuits in human skin are activated in disease
Reynolds, G.; Vegh, P.; Fletcher, J.; Poyner, E.; Stephenson, E.; Goh, I.; Botting, R.; Huang, N.; Olabi, B.; Dubois, A.; Dixon, D.; Green, K.; Maunder, D.; Engelbert, J.; Efremova, M.; Polanski, K.; Jardine, L.; Jones, C.; Ness, T.; Horsfall, D.; McGrath, J.; Carey, C.; Popescu, D.-M.; Webb, S.; Wang, X.-n.; Sayer, B.; Park, J.-E.; Negri, V.; Belokhvostova, D.; Lynch, M.; McDonald, D.; Filby, A.; Hagai, T.; Meyer, K.; Husain, A.; Coxhead, J.; Vento-Tormo, R.; Behjati, S.; Lisgo, S.; Villani, A.-C.; Bacardit, J.; Jones, P.; OToole, E.; Ogg, G.; Rajan, N.; Reynolds, N.; Teichmann, S.; Watt, F.;
10.1101/2020.11.05.369363 — immunology — Posted on 2020-11-05
3562 Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics
Maniou, E.; Staddon, M.; Marshall, A.; Greene, N.; Copp, A.; Banerjee, S.; Galea, G.
10.1101/2020.11.02.364513 — developmental biology — Posted on 2020-11-05
3564 WNT responsive SUMOylation of ZIC5 exerts multiple effects on transcription to promote murine neural crest cell development
Ali, R. G.; Bellchambers, H. M.; Warr, N.; Ahmed, J. N.; Barratt, K. S.; Neill, K.; Diamand, K. E. M.; Arkell, R. M.
10.1101/2020.11.04.369124 — developmental biology — Posted on 2020-11-05
3565 Innervation modulates the functional connectivity between pancreatic endocrine cells
Yang, Y. H. C.; Briant, L. J. B.; Raab, C.; Mullapudi, S. T.; Maischein, H.-M.; Kawakami, K.; Stainier, D. Y.
10.1101/2020.11.04.368084 — cell biology — Posted on 2020-11-05
3566 A self-exciting point process to study multi-cellular spatial signaling patterns
Verma, A.; Jena, S.; Isakov, D. R.; Aoki, K.; Toettcher, J. E.; Engelhardt, B. E.
10.1101/2020.11.04.368001 — cell biology — Posted on 2020-11-05
3567 Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
Tzani, I.; Herrmann, N.; Carillo, S.; Spargo, C. A.; Hagan, R.; Barron, N.; Bones, J.; Dilmore, W. S.; Clarke, C.
10.1101/2020.11.04.368480 — cell biology — Posted on 2020-11-05
3568 GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Munson, M. J.; Mathai, B. J.; Trachsel, L.; Yoke Wui Ng, M.; Rodriguez de la Ballina, L.; Schultz, S.; Aman, Y.; Lystad, A. H.; Singh, S.; Singh, S.; Wesche, J.; Fang, E. F.; Simonsen, A.
10.1101/2020.11.05.369496 — cell biology — Posted on 2020-11-05
3569 An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Chawla, M.; Mukherjee, T.; Deka, A.; Chatterjee, B.; Sarkar, U. A.; Singh, A. K.; Kedia, S.; Banoth, B.; Biswas, S. K.; Ahuja, V.; Basak, S.
10.1101/2020.11.02.365890 — immunology — Posted on 2020-11-05
3571 Estimating latent positions of actors using Neural Networks in R with GCN4R
Levy, J.; Bobak, C. A.; Christensen, B.; Vaickus, L. J.; O'Malley, A. J.
10.1101/2020.11.02.364935 — bioinformatics — Posted on 2020-11-05
3574 Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets
de Vries, R. D.; Schmitz, K. S.; Bovier, F. T.; Noack, D.; Haagmans, B. L.; Biswas, S.; Rockx, B.; Gellman, S. H.; Alabi, C. A.; de Swart, R. L.; MOSCONA, A.; Porotto, M.
10.1101/2020.11.04.361154 — microbiology — Posted on 2020-11-05
3576 The translational landscape of SARS-CoV-2 and infected cells
Puray-Chavez, M.; Tenneti, K.; Vuong, H. R.; Lee, N.; Liu, Y.; Horani, A.; Huang, T.; Case, J. B.; Yang, W.; Diamond, M. S.; Brody, S. L.; Dougherty, J.; Kutluay, S. B.
10.1101/2020.11.03.367516 — microbiology — Posted on 2020-11-05
3577 SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
Bailey, A. L.; Dmytrenko, O.; Greenberg, L.; Bredemeyer, A. L.; Ma, P.; Liu, J.; Penna, V.; Lai, L.; Winkler, E. S.; Sviben, S.; Brooks, E.; Nair, A. P.; Heck, K. A.; Rali, A. S.; Simpson, L.; Saririan, M.; Hobohm, D.; Stump, W. T.; Fitzpatrick, J. A.; Xie, X.; Shi, P.-Y.; Hinson, J. T.; Gi, W.-T.; Schmidt, C.; Leuschner, F.; Lin, C.-Y.; Diamond, M. S.; Greenberg, M. J.; Lavine, K. J.
10.1101/2020.11.04.364315 — immunology — Posted on 2020-11-05
3578 Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals
Mahajan, S.; Bhojak, K.; Kode, V.; Magdalene, C. M.; Manoharan, M.; Lee, K.; Ramesh, A.; V, S. H.; Srivastava, A.; Sathian, R.; Kumar, P.; Khan, T.; Chakraborty, P.; Chaudhuri, A.
10.1101/2020.11.03.367375 — immunology — Posted on 2020-11-05
3579 SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice
Pollet, J.; Chen, W.-H.; Versteeg, L.; Keegan, B.; Zhan, B.; Wei, J.; Liu, Z.; Lee, J.; Kundu, R.; Adhikari, R.; Poveda, C.; Villar Mondragon, M. J.; de Araujo Leao, A. C.; Altieri Rivera, J.; Gillespie, P. M.; Strych, U.; Hotez, P. J.; Bottazzi, M. E.
10.1101/2020.11.04.367359 — immunology — Posted on 2020-11-05
3580 Evolution of Antibody Immunity to SARS-CoV-2
Gaebler, C.; Wang, Z.; Lorenzi, J. C. C.; Muecksch, F.; Finkin, S.; Tokuyama, M.; Ladinsky, M.; Cho, A.; Jankovic, M.; Schaefer-Babajew, D.; Oliveira, T. Y.; Cipolla, M.; Viant, C.; Barnes, C. O.; Hurley, A.; Turroja, M.; Gordon, K.; Millard, K. G.; Ramos, V.; Schmidt, F.; Weisblum, Y.; Jha, D.; Tankelevich, M.; Yee, J.; Shimeliovich, I.; Robbiani, D. F.; Zhao, Z.; Gazumyan, A.; Hatziioannou, T.; Bjorkman, P. J.; Mehandru, S.; Bieniasz, P. D.; Caskey, M.; Nussenzweig, M. C.
10.1101/2020.11.03.367391 — immunology — Posted on 2020-11-05
3581 DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity
Boyle, W. K.; Richards, C.; Dulebohn, D. P.; Zalud, A. K.; Shaw, J. A.; Lovas, S.; Gherardini, F. C.; Bourret, T. J.
10.1101/2020.11.04.367946 — microbiology — Posted on 2020-11-04
3584 Feedback inhibition of AMT1 NH4+-transporters mediated by CIPK15 kinase
Chen, H.-Y.; Chen, Y.-N.; Wang, H.-Y.; Liu, Z.-T.; Frommer, W. B.; Ho, C.-H.
10.1101/2020.11.03.367383 — plant biology — Posted on 2020-11-04
3585 Root and canopy traits and adaptability genes explain drought tolerance mechanism in winter wheat.
Nehe, A.; Foulkes, J.; Ozturk, I.; Awais, R.; York, L.; Kefauver, S.; Ozdemir, F.; Morgunov, A.
10.1101/2020.11.04.367904 — plant biology — Posted on 2020-11-04
3588 Human-specific expansion of 22q11.2 low copy repeats
Vervoort, L.; Vermeesch, J. R.; Dierckxsens, N.; Pereboom, Z.; Rocchi, M.; Capozzi, O.; Shaikh, T. H.
10.1101/2020.11.04.367920 — genetics — Posted on 2020-11-04
3595 Modulating glial genes involved in synaptic function mitigates pathogenesis and behavioral deficits in a Drosophila model of Huntington's Disease
Onur, T. S.; Laitman, A.; Zhao, H.; Keyho, R.; Kim, H.; Wang, J.; Mair, M.; Perez, A.; de Haro, M.; Wang, H.; Wan, Y.-W.; Allen, G.; Lu, B.; Al-Ramahi, I.; Liu, Z.; Botas, J.
10.1101/2020.11.03.367326 — systems biology — Posted on 2020-11-04
3598 9p21 Loss Defines the Evolutionary Patterns of Aggressive Renal Cell Carcinomas
Carbone, F.; Huang, J. K.; Perelli, L.; Del Poggetto, E.; Gutschner, T.; Tomihara, H.; Soeung, M.; Lam, T. N. A.; Xia, R.; Zhu, C.; Song, X.; Zhang, J.; Sircar, K.; Malouf, G. G.; Sgambato, A.; Karam, J. A.; Gao, J.; Jonasch, E.; Viale, A.; Draetta, G. F.; Futreal, A.; Bakouny, Z.; Van Allen, E. M.; Choueiri, T.; Msaouel, P.; Litchfield, K.; Turajlic, S.; Heffernan, T. P.; Chen, Y. B.; DiNatale, R. G.; Hakimi, A. A.; Bristow, C. A.; Tannir, N. M.; Carugo, A.; Genovese, G.
10.1101/2020.11.03.367433 — cancer biology — Posted on 2020-11-04
3599 Spatial structure impacts adaptive therapy by shaping intra-tumoral competition
Strobl, M. A. R.; Gallaher, J.; West, J.; Robertson-Tessi, M.; Maini, P. K.; Anderson, A.
10.1101/2020.11.03.365163 — cancer biology — Posted on 2020-11-04
3600 A Versatile Oblique Plane Microscope for Large-Scale and High-Resolution Imaging of Subcellular Dynamics.
Sapoznik, E.; Chang, B.-J.; Huh, J.; Ju, R. J.; Azarova, E.; Pohlkamp, T.; Welf, E. S.; Broadbent, D.; Carisey, A. F.; Stehbens, S. J.; Lee, K.-m.; Marin, A.; Hanker, A. B.; Schmidt, J. C.; Arteaga, C. L.; Yang, B.; Kobayashi, Y.; Tata, P. R.; Kruithoff, R.; Doubrovinski, K.; Shepherd, D. P.; Millett-Sikking, A.; York, A. G.; Dean, K. M.; Fiolka, R. P.
10.1101/2020.04.07.030569 — biophysics — Posted on 2020-11-04
3605 Lymphocyte-Specific Biomarkers Associated with Preterm Birth and Bronchopulmonary Dysplasia
Bhattacharya, S.; Mereness, J.; Baran, A.; Misra, R.; Peterson, D.; Ryan, R.; Reynolds, A. M.; Pryhuber, G.; Mariani, T. J.
10.1101/2020.11.03.367201 — genomics — Posted on 2020-11-04
3606 Analysis Of Polycerate Mutants Reveals The Evolutionary Co-Option Of HOXD1 To Determine The Number And Topology Of Horns In Bovidae
Allais-Bonnet, A.; Hintermann, A.; Deloche, M.-C.; Cornette, R.; Bardou, P.; Naval-Sanchez, M.; Pinton, A.; Haruda, A.; Grohs, C.; Zakany, J.; Bigi, D.; Medugorac, I.; Putelat, O.; Greyvenstein, O.; Hadfield, T.; Ben Jemaa, S.; Bunevski, G.; Menzi, F.; Hirter, N.; Paris, J. M.; Hedges, J.; Palhiere, I.; Rupp, R.; Lenstra, J. A.; Gidney, L.; Lesur, J.; Schafberg, R.; Stache, M.; Wandhammer, M.-D.; Arbogast, R.-M.; Guintard, C.; Blin, A.; Boukadiri, A.; Riviere, J.; Esquerre, D.; Donnadieu, C.; Danchin-Burge, C.; Reich, C. M.; Riley, D.; van Marle-Koster, E.; Cockett, N.; Hayes, B. J. A.; Droege
10.1101/2020.11.04.363069 — genomics — Posted on 2020-11-04
3607 Improved chromosome level genome assembly of the Glanville fritillary butterfly (Melitaea cinxia) based on SMRT Sequencing and linkage map.
Blande, D.; Smolander, O.-P.; Ahola, V.; Rastas, P.; Tanskanen, J.; Kammonen, J. I.; Oostra, V.; Pellegrini, L.; Ikonen, S.; Dallas, T.; DiLeo, M. F.; Duplouy, A.; Duru, I. C.; Halimaa, P.; Kahilainen, A.; Kuwar, S. S.; Karenlampi, S. O.; Lafuente, E.; Luo, S.; Makkonen, J.; Nair, A.; Celorio-Mancera, M. d. l. P.; Pennanen, V.; Ruokolainen, A.; Sundell, T.; Tervahauta, A. I.; Twort, V.; van Bergen, E.; Osterman-Udd, J.; Paulin, L.; Frilander, M. J.; Auvinen, P.; Saastamoinen, M.
10.1101/2020.11.03.364950 — genomics — Posted on 2020-11-04
3611 Developmental regulation of mitotic chromosome formation revealed by condensin reporter mice
Taylor, G. C. A.; Macdonald, L. A.; Bui, M.; Scott, L.; Christodoulou, I.; Wills, J. C.; Papadopoulos, D.; Wood, A. J.
10.1101/2020.11.04.367847 — cell biology — Posted on 2020-11-04
3615 Comparative molecular and immunoregulatory analysis of extracellular vesicles from Candida albicans and Candida auris.
Zamith-Miranda, D.; Heyman, H. M.; Couvillion, S. P.; Cordero, R. J. B.; Rodrigues, M.; Nimrichter, L.; Casadevall, A.; Amatuzzi, R.; Alves, L. R.; Nakayasu, E. S.; Nosanchuk, J. D.
10.1101/2020.11.04.368472 — microbiology — Posted on 2020-11-04
3616 Genomic and morphologic characterization of a planktonic Thiovulum (Campylobacterota) dominating the surface waters of the sulfidic Movile Cave, Romania
Bizic, M.; Brad, T.; Barbu-Tudoran, L.; Aerts, J.; Ionescu, D.; Popa, R.; Ody, J.; Flot, J.-F.; Tighe, S.; Vellone, D.; Sarbu, S. M.
10.1101/2020.11.04.367730 — microbiology — Posted on 2020-11-04
3620 Wing shape evolution in bombycoid moths reveals two distinct strategies for maneuverable flight
Aiello, B. R.; Sikandar, U. B.; Minoguchi, H.; Kimball, K.; Hamilton, C. A.; Kawahara, A. Y.; Sponberg, S.
10.1101/2020.10.27.358176 — physiology — Posted on 2020-11-04
3621 CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations
Bharadhwaj, V. S.; Ali, M.; Birkenbihl, C.; Mubeen, S.; Lehmann, J.; Hofmann-Apitius, M.; Hoyt, C. T.; Domingo-Fernandez, D.
10.1101/2020.08.20.259226 — bioinformatics — Posted on 2020-11-04
3626 Copy number-aware deconvolution of tumor-normal DNA methylation profiles
Larose Cadieux, E.; Tanic, M.; Wilson, G. A.; Baker, T.; Dietzen, M.; Dhami, P.; Vaikkinen, H.; Watkins, T. B. K.; Kanu, N.; Veeriah, S.; Jamal-Hanjani, M.; McGranahan, N.; Feber, A.; Swanton, C.; TRACERx Consortium, ; Beck, S.; Demeulemeester, J.; Van Loo, P.
10.1101/2020.11.03.366252 — genomics — Posted on 2020-11-04
3627 Epigenomic reprogramming of repetitive noncoding RNAs and IFN-stimulated genes by mutant KRAS
Reggiardo, R. E.; Velandi Maroli, S.; Halasz, H.; Ozen, M.; Carrillo, D.; LaMontagne, E.; Whitehead, L.; Kim, E.; Malik, S.; Fernandes, J.; Marinov, G.; Collisson, E.; Demirci, U.; Kim, D. H.
10.1101/2020.11.04.367771 — genomics — Posted on 2020-11-04
3628 PROXIMATE AND GENETIC ANALYSIS OF BLACKFIN TUNA (T. atlanticus)
Nunez Mata, Y. M.; Rios Rodriguez, J. R.; Perales Torres, A. L.; De la Rosa Reyna, X. F.; Vazquez Rodriguez, J. A.; Fernandez Santos, N. A.; Martinez Montoya, H.
10.1101/2020.11.03.366153 — genetics — Posted on 2020-11-04
3630 Long-range gene regulation network of the MGMT enhancer in modulating glioma cell sensitivity to temozolomide
He, A.; Chen, B.; Bi, J.; Wang, W.; Chen, J.; Qian, Y.; Shi, T.; Zhao, Z.; Shi, J.; Yang, H.; Zhang, L.; Lu, W.
10.1101/2020.11.03.367268 — genetics — Posted on 2020-11-04
3631 Molecular Evolution of Podocyte Slit-diaphragm Proteins
Mulukala, S. N.; Kambhampati, V.; Qadri, A. S.; Pasupulati, A. k.
10.1101/2020.11.03.366161 — evolutionary biology — Posted on 2020-11-04
3633 Environmental factors drive release of Perkinsus marinus from infected oysters
Gignoux-Wolfsohn, S. A.; Newcomb, M. S. R.; Ruiz, G. M.; Pagenkopp Lohan, K. M.
10.1101/2020.11.03.366781 — ecology — Posted on 2020-11-04
3634 Integrated Use of Compost and Nitrogen Fertilizer and their Effects on Yield and Yield Components of Wheat: A Pot Experiment
Gari, B. D.; Berecha, G.; Mamuye, M.; Diriba, O. H.; Nebiyu, A.; Nigussie, A.; Hanc, A.; Svehla, P.
10.1101/2020.10.07.329524 — ecology — Posted on 2020-11-04
3636 Human Chr18: "Stakhanovite" Genes, Missing and uPE1 Proteins in Liver Tissue and HepG2 Cells
Krasnov, G. S.; Lisitsa, A. V.; Ponomarenko, E. A.; Radko, S. P.; Ptitsyn, K. G.; Shapovalova, V. V.; Timoshenko, O. S.; Khmeleva, S. A.; Kurbatov, L. K.; Kiseleva, Y. Y.; Ilgisonis, E. V.; Pyatnitskiy, M. A.; Poverennaya, E. V.; Kiseleva, O. I.; Vakhrushev, I. V.; Tsvetkova, A. V.; Buromski, I. V.; Markin, S. S.; Zgoda, V. G.; Archakov, A. I.
10.1101/2020.11.04.358739 — molecular biology — Posted on 2020-11-04
3637 Aurora-A phosphorylates splicing factors and regulates alternative splicing
Damodaran, A. P.; Gavard, O.; Gagne, J.-P.; Rogalska, M. E.; Mancini, E.; Courtheoux, T.; Cailloce, J.; Mereau, A.; Poirier, G. G.; Valcarcel, J.; Watrin, E.; Prigent, C.
10.1101/2020.11.04.368498 — molecular biology — Posted on 2020-11-04
3638 The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis
Deruelle, V.; Bouillot, S.; Job, V.; Taillebourg, E.; Fauvarque, M.-O.; Attree, I.; Huber, P.
10.1101/2020.11.04.367706 — microbiology — Posted on 2020-11-04
3640 Muscle Atrophy: Different Strains of Mice Respond Differently to Single Limb Immobilization
Maroni, C.; Friedman, M.; Zhang, Y.; McClure, M.; Fulle, S.; Farber, C.; Donahue, H.
10.1101/2020.11.03.367169 — physiology — Posted on 2020-11-04
3646 Derivation of predator functional responses using a mechanistic approach in a natural system
Beardsell, A.; Gravel, D.; Berteaux, D.; Gauthier, G.; Clermont, J.; Careau, V.; Lecomte, N.; Juhasz, C.-C.; Royer-Boutin, P.; Bety, J.
10.1101/2020.11.04.368670 — ecology — Posted on 2020-11-04
3647 Using Community Science to Reveal the Global Chemogeography of River Metabolomes
Garayburu-Caruso, V. A.; Danczak, R. E.; Stegen, J.; Renteria, L.; MacCall, M.; Goldman, A. E.; Chu, R. K.; Toyoda, J.; Resch, C. T.; Torgeson, J. M.; Wells, J.; Fansler, S.; Kumar, S.; Graham, E. B.
10.1101/2020.11.02.362905 — ecology — Posted on 2020-11-04
3648 Genetically encoded ratiometric biosensor for probing lysosomal pH in mammalian cells and C. elegans
Chin, M. Y.; Patwardhan, A. R.; Ang, K.-H.; Wang, A. L.; Alquezar, C.; Welch, M.; Grabe, M.; Arkin, M. R.; Kao, A. W.
10.1101/2020.11.04.368654 — cell biology — Posted on 2020-11-04
3649 Diversity of ACE2 and its interaction with SARS-CoV-2 receptor binding domain
Gan, J. L.; Huang, R.; Warner, G.; Kelley, A.; McGregor, D.; Smider, V. V.
10.1101/2020.10.25.354548 — molecular biology — Posted on 2020-11-04
3651 Strong coupling and local control of dimensionality across brain areas
Dahmen, D.; Recanatesi, S.; Ocker, G. K.; Jia, X.; Helias, M.; Shea-Brown, E.
10.1101/2020.11.02.365072 — neuroscience — Posted on 2020-11-04
3652 Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates
Klein, A.; Solinski, H. J.; Malewicz, N.; Ieong, H. F.-h.; Shimada, S.; Hartke, T. V.; Wooten, M.; Wu, G.; Hoon, M. A.; LaMotte, R. H.; Ringkamp, M.
10.1101/2020.11.04.368597 — neuroscience — Posted on 2020-11-04
3654 Brain volumetric changes in the general population following the COVID-19 outbreak and lockdown
Salomon, T.; Cohen, A.; Barazany, D.; Ben-Zvi, G.; Botvinik-Nezer, R.; Gera, R.; Oren, S.; Roll, D.; Rozic, G.; Saliy, A.; Tik, N.; Tsarfati, G.; Tavor, I.; Schonberg, T.; Assaf, Y.
10.1101/2020.09.08.285007 — neuroscience — Posted on 2020-11-04
3655 Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy
Barone, S. M.; Paul, A. G. A.; Muehling, L. M.; Lannigan, J. A.; Kwok, W. W.; Turner, R. B.; Woodfolk, J. A.; Irish, J. M.
10.1101/2020.07.31.190454 — systems biology — Posted on 2020-11-04
3657 Transcriptome atlas of Phalaenopsis equestris
Klepikova, A. V.; Kasianov, A. S.; Ezhova, M. A.; Penin, A. A.; Logacheva, M. D.
10.1101/2020.11.03.366260 — plant biology — Posted on 2020-11-04
3658 Data driven mathematical model of colon cancer progression
Kirshtein, A.; Akbarinejad, S.; Hao, W.; Le, T.; Aronow, R. A.; Shahriyari, L.
10.1101/2020.11.02.365668 — cancer biology — Posted on 2020-11-04
3659 E-cadherin promotes cell hyper-proliferation in breast cancer
Russo, G. C.; Karl, M. N.; Clark, D.; Cui, J.; Carney, R.; Su, B.; Starich, B. A.; Lih, T.-S.; Zhang, Q.; Wu, P.-h.; Lee, M.-H.; Leong, H. S.; Zhang, H.; Wirtz, D.
10.1101/2020.11.04.368746 — cancer biology — Posted on 2020-11-04
3660 Strengthening the BioCompute Standard by Crowdsourcing on PrecisionFDA
Stephens, S. H.; King, C. H.; Watford, S.; Patel, J.; Dean, D. A.; Koc, S.; Xiao, N.; Donaldson, E.; Thompson, E.; Purkayastha, A.; Mazumder, R.; Johanson, E.; Keeney, J.
10.1101/2020.11.02.365528 — bioinformatics — Posted on 2020-11-04
3662 LyGo: A platform for rapid screening of lytic polysaccharide monooxygenase production
Hernandez-Rollan, C.; Falkenberg, K. B.; Rennig, M.; Bertelsen, A. B.; Ipsen, J. O.; Brander, S.; Daley, D. O.; Johansen, K. S.; Norholm, M. H. H.
10.1101/2020.11.04.368555 — bioengineering — Posted on 2020-11-04
3665 Polygenic Scores Predict the Development of Alcohol and Nicotine Use Problems from Adolescence through Young Adulthood
Deak, J. D.; Clark, D. A.; Liu, M.; Durbin, C. E.; Iacono, W. G.; McGue, M.; Vrieze, S. I.; Hicks, B. M.
10.1101/2020.07.29.227439 — genetics — Posted on 2020-11-04
3666 Essential histone chaperones collaborate to regulate transcription and chromatin integrity
Viktorovskaya, O.; Chuang, J.; Jain, D.; Reim, N. I.; Lopez-Rivera, F.; Murawska, M.; Spatt, D.; Churchman, L. S.; Park, P. J.; Winston, F.
10.1101/2020.11.04.368589 — genetics — Posted on 2020-11-04
3669 Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus
Gopal, V.; Nilsson-Payant, B. E.; French, H.; Siegers, J. Y.; tenOever, B.; Yung, W.-s.; Hardwick, M.; te Velthuis, A. J. W.
10.1101/2020.11.02.365833 — microbiology — Posted on 2020-11-04
3670 Synergistic Coding of Human Odorants in the Mosquito Brain
Shankar, S.; Tauxe, G. M.; Spikol, E. D.; Li, M.; Akbari, O. S.; Giraldo, D.; McMeniman, C. J.
10.1101/2020.11.02.365916 — neuroscience — Posted on 2020-11-04
3671 Plasticity in visual cortex is disrupted in a mouse model of tauopathy and neurodegeneration
Papanikolaou, A.; Rodrigues, F. R.; Holeniewska, J.; Phillips, K. G.; Saleem, A. B.; Solomon, S. G.
10.1101/2020.11.02.365767 — neuroscience — Posted on 2020-11-04
3678 Transdiagnostic dimensions of psychopathology explain individuals' unique deviations from normative neurodevelopment in brain structure
Parkes, L.; Moore, T. M.; Calkins, M. E.; Cook, P. A.; Cieslak, M.; Roalf, D. R.; Wolf, D. H.; Gur, R. C.; Gur, R. E.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2020.06.11.147009 — neuroscience — Posted on 2020-11-04
3679 Neural circuit basis of aversive odour processing in Drosophila from sensory input to descending output.
Huoviala, P.; Dolan, M.-J.; Love, F.; Myers, P.; Frechter, S.; Namiki, S.; Pettersson, L.; Roberts, R. J. V.; Turnbull, R.; Mitrevica, Z.; Breads, P.; Schlegel, P.; Bates, A. S. S.; Rodrigues, T.; Aso, Y.; Bock, D.; Rubin, G. M.; Stensmyr, M.; Card, G.; Costa, M.; Jefferis, G. S. X. E.
10.1101/394403 — neuroscience — Posted on 2020-11-04
3681 Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease
Youlten, S. E.; Kemp, J. P.; Logan, J. G.; Ghirardello, E. J.; Sergio, C. M.; Dack, M. R. G.; Guilfoyle, S. E.; Leitch, V. D.; Butterfield, N. C.; Komla-Ebri, D.; Chai, R. C.; Corr, A. P.; Smith, J. T.; Mohanty, S. T.; Morris, J. A.; McDonald, M. M.; Quinn, J. M. W.; McGlade, A. R.; Bartonicek, N.; Jansson, M.; Hatzikotoulas, K.; Irving, M. D.; Beleza-Meireles, A.; Rivadeneira, F.; Duncan, E. L.; Richards, J. B.; Adams, D. J.; Lelliott, C. J.; Brink, R.; Phan, T. G.; Eisman, J. A.; Evans, D. M.; Zeggini, E.; Baldock, P. A.; Bassett, J. H. D.; Williams, G. R.; Croucher, P. I.
10.1101/2020.04.20.051409 — systems biology — Posted on 2020-11-04
3682 RuBisCO adaptation is more limited by phylogenetic constraint than by catalytic trade-off in plants
Bouvier, J. W.; Emms, D. M.; Rhodes, T.; Nielsen, J. R.; Bolton, J. S.; Eddershaw, A.; Brasnett, A.; Unitt, A.; Whitney, S. M.; Kelly, S.
10.1101/2020.09.15.298075 — plant biology — Posted on 2020-11-04
3685 Connection Stripes in the Primate Insula
Krockenberger, M.; Saleh, T. O.; Logothetis, N. K.; Evrard, H. C.
10.1101/2020.11.03.361055 — neuroscience — Posted on 2020-11-04
3688 Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients
Filbin, M. R.; Mehta, A.; Schneider, A. M.; Kays, K. R.; Guess, J. R.; Gentili, M.; Fenyves, B. G.; Charland, N. C.; Gonye, A. L. K.; Gushterova, I.; Khanna, H. K.; LaSalle, T. J.; Lavin-Parsons, K. M.; Lilley, B. M.; Lodenstein, C. L.; Manakongtreecheep, K.; Margolin, J. D.; McKaig, B. N.; Rojas-Lopez, M.; Russo, B. C.; Sharma, N.; Tantivit, J.; Thomas, M. F.; Gerszten, R. E.; Heimberg, G. S.; Hoover, P. J.; Lieb, D. J.; Lin, B.; Ngo, D.; Pelka, K.; Reyes, M.; Smillie, C. S.; Waghray, A.; Wood, T. E.; Zajac, A. S.; Jennings, L. J.; Grundberg, I.; Bhattacharyya, R. P.; Parry, B. A.; Villani, A
10.1101/2020.11.02.365536 — systems biology — Posted on 2020-11-04
3691 Multi-compartment tumor organoids
Lee, M.-H.; Rahmanto, Y. S.; Russo, G. C.; Wu, P.-h.; Gilkes, D.; Kiemen, A.; Miyamoto, T.; Yu, Y.; Habibi, M.; Shih, I.-M.; Wang, T.-L.; Wirtz, D.
10.1101/2020.11.03.367334 — cancer biology — Posted on 2020-11-04
3692 Protein Structural Alignments From Sequence
Morton, J.; Strauss, C.; Blackwell, R.; Berenberg, D.; Gligorijevic, V.; Bonneau, R.
10.1101/2020.11.03.365932 — bioinformatics — Posted on 2020-11-04
3694 Targeted long-read sequencing resolves complex structural variants and identifies missing disease-causing variants
Miller, D. E.; Sulovari, A.; Wang, T.; Loucks, H.; Hoekzema, K.; Munson, K. M.; Lewis, A. P.; Almanza Fuerte, E. P.; Paschal, C. R.; Thies, J.; Bennett, J. T.; Glass, I.; Dipple, K. M.; Patterson, K.; Bonkowski, E. S.; Nelson, Z.; Squire, A.; Sikes, M.; Beckman, E.; Bennett, R. L.; Earl, D.; Lee, W.; Allikmets, R.; Perlman, S. J.; Chow, P.; Hing, A. V.; Adam, M. P.; Sun, A.; Lam, C.; Chang, I.; University of Washington Center for Mendelian Genomics, ; Cherry, T.; Chong, J. X.; Bamshad, M. J.; Nickerson, D. A.; Mefford, H. C.; Doherty, D.; Eichler, E. E.
10.1101/2020.11.03.365395 — genomics — Posted on 2020-11-04
3697 Analysing the Yeast Complexome - The Complex Portal rising to the challenge
Meldal, B. H. M.; Pons, C.; Perfetto, L.; del-Toro, N.; Wong, E.; Aloy, P.; Hermjakob, H.; Orchard, S.; Porras, P.
10.1101/2020.11.03.367086 — systems biology — Posted on 2020-11-04
3701 Disinhibition mediated by reciprocal hypothalamic and raphe GABAergic projections promotes wakefulness
Gazea, M.; Furdan, S.; Sere, P.; Oesch, L.; Molnár, B.; Di Giovanni, G. D.; Adamantidis, A. R.; Lorincz, M. L.
10.1101/2020.11.04.367722 — neuroscience — Posted on 2020-11-04
3703 Titan mice are a unique bred mammalian model to study obesity and aspects of metabolic syndrome
de-Diego, I.; Sanz-Moreno, A.; Müller-Eigner, A.; Venkateswaran Venkatasubramani, A.; Langhammer, M.; Gerlini, R.; Rathkolb, B.; Aguilar-Pimentel, A.; Klein-Rodewald, T.; Calzada-Wack, J.; Becker, L.; Imhof, A.; Meng, C.; Ludwig, C.; Koch, F.; Caton, V.; Brenmoehl, J.; Fuchs, H.; Gailus-Durner, V.; Hoeflich, A.; Hrabe de Angelis, M.; Peleg, S.
10.1101/2020.05.11.088625 — biochemistry — Posted on 2020-11-04
3704 A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection
Cattel, J.; Haberkorn, C.; Laporte, F.; Gaude, T.; Cumer, T.; Renaud, J.; Sutherland, I. W.; Hertz, J. C.; Bonneville, J.-M.; Arnaud, V.; Nous, C.; Fustec, B.; Boyer, S.; Marcombe, S.; David, J.-P.
10.1101/2020.06.08.139741 — evolutionary biology — Posted on 2020-11-04
3705 Human Dicer helicase domain recruits PKR and dsRNA binding proteins during viral infection
Montavon, T. C.; Baldaccini, M.; Lefevre, M.; Girardi, E.; Chane-Woon-Ming, B.; Messmer, M.; Hammann, P.; Chicher, J.; Pfeffer, S.
10.1101/2020.05.14.095356 — microbiology — Posted on 2020-11-04
3706 The composition of the microbiota in the full-term fetal gut and amniotic fluid: a bovine caesarean section study
Husso, A.; Lietaer, L.; Pessa-Morikawa, T.; Grönthal, T.; Govaere, J.; Van Soom, A.; Iivanainen, A.; Opsomer, G.; Niku, M.
10.1101/2020.09.28.309476 — microbiology — Posted on 2020-11-04
3711 Nitrogen Availability Modulates the Host Control of the Barley Rhizosphere Microbiota.
Alegria Terrazas, R.; Robertson-Albertyn, S.; Corral, A. M.; Escudero-Martinez, C.; Balbirnie-Cumming, K.; Morris, J.; Hedley, P. E.; Paterson, E.; Baggs, L. M.; Abbott, J.; Bulgarelli, D.
10.1101/605204 — plant biology — Posted on 2020-11-04
3712 Prediction of vascular ageing based on smartphone acquired PPG signals
Dall'Olio, L.; Curti, N.; Remondini, D.; Harb, Y. S.; Asselbergs, F. W.; Castellani, G.; Uh, H.-W.
10.1101/2020.05.26.116186 — biophysics — Posted on 2020-11-04
3715 Glypicans specifically regulate Hedgehog signaling through their interaction with Ihog in cytonemes
Simon, E.; Jimenez-Jimenez, C.; Seijo-Barandiaran, I.; Aguilar, G.; Sanchez-Hernandez, D.; Aguirre-Tamaral, A.; Gonzalez-Mendez, L.; Ripoll, P.; Guerrero, I.
10.1101/2020.11.04.367797 — developmental biology — Posted on 2020-11-04
3716 ASPP2/PP1 complexes maintain the integrity of pseudostratified epithelia undergoing remodelling during morphogenesis
Royer, C.; Sandham, E.; Slee, E.; Godwin, J.; Veits, N.; Hathrell, H.; Zhou, F.; Leonavicius, K.; Garratt, J.; Narendra, T.; Vincent, A.; Jones, C.; Child, T.; Coward, K.; Graham, C.; Lu, X.; Srinivas, S.
10.1101/2020.11.03.366906 — developmental biology — Posted on 2020-11-04
3717 The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates
Elsafi Mabrouk, M. H.; Goetzke, R.; Abagnale, G.; Yesilyurt, B.; Salz, L.; Zeevaert, K.; Ma, Z.; Toledo, M. A. S.; Li, R.; Costa, I. G.; Pachauri, V.; Schnakenberg, U.; Zenke, M.; Wagner, W.
10.1101/2020.11.03.366518 — cell biology — Posted on 2020-11-04
3718 The mitochondrial permeability transition pore activates a maladaptive mitochondrial unfolded protein response
Angeli, S.; Foulger, A.; Peiris, T. H.; Gerencser, A.; Chamoli, M.; Bhaumik, D.; Shahmirzadi, A. A.; Andersen, J.; Lithgow, G.
10.1101/2020.11.03.366815 — cell biology — Posted on 2020-11-04
3719 Role and Dynamics of Vacuolar pH during Cell-in-Cell mediated Death
Su, Y.; Ren, H.; Tang, M.; Zheng, Y.; Zhang, B.; Wang, C.; Hou, X.; Niu, Z.; Gao, L.; Chen, Z.; Luo, T.; Sun, Q.
10.1101/2020.11.03.364877 — cell biology — Posted on 2020-11-04
3720 Role of an atypical cadherin gene, Cdh23 in prepulse inhibition and its implication in schizophrenia
Balan, S.; Ohnishi, T.; Watanabe, A.; Ohba, H.; Iwayama, Y.; Toyoshima, M.; Hara, T.; Hisano, Y.; Miyasaka, Y.; Toyota, T.; Shimamoto-Mitsuyama, C.; Maekawa, M.; Numata, S.; Ohmori, T.; Shimogori, T.; Kikkawa, Y.; Hayashi, T.; Yoshikawa, T.
10.1101/2020.10.29.360180 — genetics — Posted on 2020-11-04
3722 Differential functional neural circuitry behind autism subtypes with marked imbalance between social-communicative and restricted repetitive behavior symptom domains
Bertelsen, N.; Landi, I.; Bethlehem, R. A. I.; Seidlitz, J.; Busuoli, E. M.; Mandelli, V.; Satta, E.; Trakoshis, S.; Auyeung, B.; Kundu, P.; Loth, E.; Dumas, G.; Baumeister, S.; Beckmann, C. F.; Bolte, S.; Bourgeron, T.; Charman, T.; Durston, S.; Ecker, C.; Holt, R.; Johnson, M. H.; Jones, E. J. H.; Mason, L.; Meyer-Lindenberg, A.; Moessnang, C.; Oldehinkel, M.; Persico, A.; Tillmann, J.; Williams, S. C. R.; Spooren, W.; Murphy, D. G. M.; Buitelaar, J. K.; EU-AIMS LEAP group, ; Baron-Cohen, S.; Lai, M.-C.; Lombardo, M. V.
10.1101/2020.05.08.083758 — neuroscience — Posted on 2020-11-04
3723 Transcriptional Network Orchestrating Regional Patterning of Cortical Progenitors
Ypsilanti, A. R.; Pattabiraman, K.; Catta-Preta, R.; Golonzhka, O.; Lindtner, S.; Tang, K.; Jones, I.; Abnousi, A.; Juric, I.; Hu, M.; Shen, Y.; Dickel, D. E.; Visel, A.; Pennachio, L. A.; Hawrylycz, M.; Thompson, C.; Zeng, H.; Barozzi, I.; Nord, A. S.; Rubenstein, J. L. R.
10.1101/2020.11.03.366914 — neuroscience — Posted on 2020-11-04
3724 Heritability of cortical morphology reflects a sensory-fugal plasticity gradient
Vainik, U.; Paquola, C.; Wang, X.; Zheng, Y.-Q.; Bernhardt, B.; Misic, B.; Dagher, A.
10.1101/2020.11.03.366419 — neuroscience — Posted on 2020-11-04
3728 Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes
Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.
10.1101/705285 — genomics — Posted on 2020-11-03
3729 Morphological stasis masks ecologically divergent coral species on tropical reefs
Bongaerts, P.; Cooke, I. R.; Ying, H.; Wels, D.; den Haan, S.; Hernandez-Agreda, A.; Brunner, C. A.; Dove, S.; Englebert, N.; Eyal, G.; Foret, S.; Grinblat, M.; Hay, K. B.; Harii, S.; Hayward, D. C.; Lin, Y.; Mihaljevic, M.; Moya, A.; Muir, P.; Sinniger, F.; Smallhorn-West, P.; Torda, G.; Ragan, M. A.; van Oppen, M. J.; Hoegh-Guldberg, O.
10.1101/2020.09.04.260208 — evolutionary biology — Posted on 2020-11-03
3730 One Health, One Hive: A scoping review of honey bees, climate change, pollutants, and antimicrobial resistance
de Jongh, E. J.; Harper, S. L.; Yamamoto, S. S.; Wright, C. J.; Wilkinson, C. W.; Ghosh, S.; Otto, S. J. G.
10.1101/2020.11.03.366377 — ecology — Posted on 2020-11-03
3738 Pancreatic cancer stem cells (CSCs) are regulated via a feedback-loop of telomerase activity and stemness factors
Walter, K.; Rodriguez-Aznar, E.; Ventura-Ferreira, M. S.; Frappant, P. O.; Dittrich, T.; Tiwary, K.; Meessen, S.; Lerma, L.; Schulte, L. A.; Arnold, F.; Azoitei, N.; Erkan, M.; Lehel, A.; Bruemmendorf, T.; Seufferlein, T.; Kleger, A.; Tabares, E.; Guenes, C.; Beier, F.; Sainz, B.; Hermann, P. C.
10.1101/2020.11.02.361931 — cancer biology — Posted on 2020-11-03
3741 Overcoming Resistance to BRAFV600E Inhibition in Melanoma by Deciphering and Targeting Personalized Protein Network Alterations
Vasudevan, S.; Flashner-Abramson, E.; Adejumobi, I.; Vilencki, D.; Stefansky, S.; Rubinstein, A. M.; Kravchenko-Balasha, N.
10.1101/2020.11.03.366245 — systems biology — Posted on 2020-11-03
3742 Seeking an optimal dosing regimen for OZ439-DSM265 combination therapy for treating uncomplicated falciparum malaria
Dini, S.; Zaloumis, S. G.; Price, D. J.; Gobeau, N.; Kuemmel, A.; Cherkaoui, M.; Moehrle, J. J.; McCarthy, J. S.; Simpson, J. A.
10.1101/2020.11.02.366112 — pharmacology and toxicology — Posted on 2020-11-03
3743 Intraspecific variation in symbiont density in an insect-microbe symbiosis
Parker, B. J.; Hrcek, J.; McLean, A. H. C.; Brisson, J. A.; Godfray, H. C. J.
10.1101/2020.11.03.365353 — evolutionary biology — Posted on 2020-11-03
3744 Identification of novel disease relevant genetic modifiers affecting the SHH pathway in the developing brain
Mecklenburg, N.; Kowalczyk, I.; Witte, F.; Goerne, J.; Laier, A.; Gonschior, H.; Lehmann, M.; Richter, M.; Sporbert, A.; Purfuerst, B.; Hubner, N.; Hammes, A.
10.1101/2020.11.03.366302 — developmental biology — Posted on 2020-11-03
3748 The Hsc70 Disaggregation Machinery RemovesMonomer Units Directly from α-Synuclein FibrilEnds
Schneider, M. M.; Gautam, S.; Herling, T. W.; Andrzejwska, E.; Krainer, G.; Miller, A. M.; Peter, Q. A. E.; Ruggeri, F. S.; Vendruscolo, M.; Bracher, A.; Dobson, C. M.; Hartl, F.-U.; Knowles, T.
10.1101/2020.11.02.365825 — biophysics — Posted on 2020-11-03
3749 Senotherapeutic peptide reduces skin biological age and improves skin health markers
Zonari, A.; Brace, L. E.; Al-Katib, K. Z.; Porto, W. F.; Foyt, D.; Guiang, M.; Cruz, E. A. O.; Marshall, B.; Salgueiro, W. G.; Inan, M. D.; Rahman, M.; Anupom, T.; Vanapalli, S.; Mori, M. A.; Franco, O. L.; Oliveira, C. R.; Boroni, M.; Carvalho, J. L.
10.1101/2020.10.30.362822 — bioengineering — Posted on 2020-11-03
3750 Properties of genes encoding transfer RNAs as integration sites for genomic islands and prophages in Klebsiella pneumoniae
Berrios-Pasten, C.; Acevedo, R.; Arros, P.; Varas, M. A.; Wyres, K. L.; Lam, M. M.; Holt, K. E.; Lagos, R.; Marcoleta, A. E.
10.1101/2020.11.02.365908 — genomics — Posted on 2020-11-03
3751 Paraspeckles are constructed as block copolymer micelles through microphase separation
Yamazaki, T.; Yamamoto, T.; Yoshino, H.; Souquere, S.; Nakagawa, S.; Pierron, G.; Hirose, T.
10.1101/2020.11.02.366021 — molecular biology — Posted on 2020-11-03
3754 Forkhead box R1-mediated stress response linked to a case of human microcephaly and brain atrophy
Mota, A.; Hong, R.; Niu, S.-Y.; Bertherat, F.; Wolfe, L.; Malicdan, C. M.; Markello, T. C.; Adams, D. R.; Gahl, W. A.; Cheng, C.; Beffert, U.; Ho, A.
10.1101/2020.11.03.366740 — molecular biology — Posted on 2020-11-03
3755 Control of neurogenic competence in mammalian hypothalamic tanycytes.
Yoo, S.; Kim, J.; Lyu, P.; Hoang, T.; Ma, A.; Trinh, V.; Dai, W.; Jiang, L.; Leavey, P.; Won, J.-K.; Park, S.-H.; Qian, J.; Brown, S. P.; Blackshaw, S.
10.1101/2020.11.02.359992 — neuroscience — Posted on 2020-11-03
3761 RAPPID: a platform of ratiometric bioluminescent sensors for homogeneous immunoassays
Ni, Y.; Rosier, B. J. H. M.; van Aalen, E. A.; Hanckmann, E. T. L.; Biewenga, L.; Makri Pistikou, A.-M.; Timmermans, B.; Vu, C.; Roos, S.; Arts, R.; Li, W.; de Greef, T. F. A.; van Kuppeveld, F. J. M.; Bosch, B.-J.; Merkx, M.
10.1101/2020.10.31.363044 — bioengineering — Posted on 2020-11-03
3762 Genome information processing by the INO80 chromatin remodeler positions nucleosomes
Oberbeckmann, E.; Krietenstein, N.; Niebauer, V.; Wang, Y.; Schall, K.; Moldt, M.; Straub, T.; Rohs, R.; Hopfner, K.-P.; Korber, P.; Eustermann, S.
10.1101/2020.11.03.366690 — biochemistry — Posted on 2020-11-03
3767 The meadow jumping mouse genome and transcriptome suggest mechanisms of hibernation
Cong, Q.; Brem, E. A.; Zhang, J.; Alföldi, J.; Johnson, J.; Karlsson, E. K.; Lindblad-Toh, K.; Malaney, J. L.; Israelsen, W. J.
10.1101/2020.11.02.365791 — genomics — Posted on 2020-11-03
3768 Plastid phylogenomics resolves ambiguous relationships within the orchid family and provides a solid timeframe for biogeography and macroevolution
Serna Sanchez, M. A.; Perez-Escobar, O. A.; Bogarin, D.; Torres, M. F.; Alvarez Yela, A. C.; Arcila Galvis, J. E.; Hall, C. F.; de Barros, F.; Pinheiro, F.; Dodsworth, S.; Chase, M. W.; Antonelli, A.; Arias, T.
10.1101/774018 — evolutionary biology — Posted on 2020-11-03
3770 Neighboring colonies influence uptake of thermotolerant endosymbionts in threatened Caribbean coral recruits
Williamson, O. M.; Allen, C. E.; Williams, D. E.; Johnson, M. W.; Miller, M. W.; Baker, A. C.
10.1101/2020.11.02.360941 — ecology — Posted on 2020-11-03
3772 The smORF-containing gene mille-pattes is required for moulting and Trypanosoma cruzi metacyclogenesis in the Chagas disease vector Rhodnius prolixus
Azevedo, C.; Rodrigues, B.; Alves, S.; Ribeiro, L.; Logullo, C.; Nepomuceno, J.; Roberto-Silva, J.; Mury, F.; Nunes-da-Fonseca, R.
10.1101/2020.10.06.324897 — molecular biology — Posted on 2020-11-03
3773 Characterization of Nonmotor Symptoms in the MitoPark Mouse Model of Parkinson's Disease
Langley, M. R.; Ghaisas, S.; Palanisamy, B.; Ay, M.; Jin, H.; Anantharam, V.; Kanthasamy, A.; Kanthasamy, A.
10.1101/2020.11.02.365874 — neuroscience — Posted on 2020-11-03
3774 ZIKA virus effects on neuroprogenitors are exacerbated by the main pyriproxyfen metabolite via thyroid hormone signaling disruption
Spirhanzlova, P.; Sebillot, A.; Vancamp, P.; Gothie, J.-D.; Le Mevel, S.; Leemans, M.; Wejaphikul, K.; Meima, M.; Mughal, B. B.; Butruille, L.; Roques, P.; Remaud, S.; Fini, J.-B.; Demeneix, B. A.
10.1101/2020.11.03.366468 — neuroscience — Posted on 2020-11-03
3775 MetaGraph: Indexing and Analysing Nucleotide Archives at Petabase-scale
Karasikov, M.; Mustafa, H.; Danciu, D.; Zimmermann, M.; Barber, C.; Ratsch, G.; Kahles, A.
10.1101/2020.10.01.322164 — bioinformatics — Posted on 2020-11-03
3777 Early immune response in mice immunized with a semi-split inactivated vaccine against SARS-CoV-2 containing S protein-free particles and subunit S protein
Petras, M.; Lesny, P.; Musil, J.; Limberkova, R.; Patikova, A.; Jirsa, M.; Krsek, D.; Brezovsky, P.; Koladiya, A.; Vanikova, S.; Mackova, B.; Jirova, D.; Krijt, M.; Lesna, I. K.; Adamkova, V.
10.1101/2020.11.03.366641 — microbiology — Posted on 2020-11-03
3778 The ACE2-binding interface of SARS-CoV-2 Spike inherently deflects immune recognition
Hattori, T.; Koide, A.; Panchenko, T.; Romero, L. A.; Teng, K. W.; Tada, T.; Landau, N. R.; Koide, S.
10.1101/2020.11.03.365270 — biochemistry — Posted on 2020-11-03
3779 Looking for pathways related to COVID-19 phenotypes: Confirmation of pathogenic mechanisms by SARS-CoV-2 - Host interactome.
Messina, F.; Giombini, E.; Montaldo, C.; Sharma, A. A.; Piacentini, M.; Zoccoli, A.; Sekaly, R. P.; Locatelli, F.; Zumla, A.; Maeurer, M.; Capobianchi, M. R.; Lauria, F. N.; Ippolito, G.
10.1101/2020.11.03.366666 — microbiology — Posted on 2020-11-03
3780 Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus
Gopal, V.; Nilsson-Payant, B. E.; French, H.; tenOever, B.; Yung, W.-s.; Hardwick, M.; te Velthuis, A.
10.1101/2020.11.02.365833 — microbiology — Posted on 2020-11-03
3781 Outer membrane lipoprotein DolP interacts with the BAM complex and promotes fitness during envelope stress response
Ranava, D.; Yang, Y.; Orenday-Tapia, L.; Rousset, F.; Turlan, C.; Cui, L.; Morales, V.; Moulin, C.; Munoz, G.; Rech, J.; Caumont-Sarcos, A.; Albenne, C.; Bikard, D.; Ieva, R.
10.1101/2020.09.23.308296 — microbiology — Posted on 2020-11-03
3783 Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients
Filbin, M. R.; Mehta, A.; Schneider, A. M.; Kays, K. R.; Guess, J. R.; Gentili, M.; Fenyves, B. G.; Charland, N. C.; Gonye, A. L. K.; Gushterova, I.; Khanna, H. K.; LaSalle, T. J.; Lavin-Parsons, K. M.; Lilley, B. M.; Lodenstein, C. L.; Manakongtreecheep, K.; Margolin, J. D.; McKaig, B. N.; Rojas-Lopez, M.; Russo, B. C.; Sharma, N.; Tantivit, J.; Thomas, M. F.; Gerszten, R. E.; Heimberg, G. S.; Hoover, P. J.; Lieb, D. J.; Lin, B.; Ngo, D.; Pelka, K.; Reyes, M.; Smillie, C. S.; Waghray, A.; Wood, T. E.; Zajac, A. S.; Jennings, L. J.; Grundberg, I.; Bhattacharyya, R. P.; Parry, B. A.; Villani, A
10.1101/2020.11.02.365536 — systems biology — Posted on 2020-11-03
3785 Modelling the active SARS-CoV-2 helicase complex as a basis for structure-based inhibitor design
Berta, D.; Badaoui, M.; Buigues, P. J.; Martino, S. A.; Pisliakov, A.; Elghobashi-Meinhardt, N.; Wells, G.; Harris, S. A.; Frezza, E.; Rosta, E.
10.1101/2020.11.03.366609 — biochemistry — Posted on 2020-11-03
3788 Antiviral activity of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro
Conzelmann, C.; Weil, T.; Gross, R.; Jungke, P.; Frank, B.; Eggers, M.; Mueller, J. A.; Muench, J.
10.1101/2020.10.30.360545 — microbiology — Posted on 2020-11-03
3790 Rapid development of SARS-CoV-2 receptor binding domain-conjugated nanoparticle vaccine candidate
Kang, Y.-F.; Sun, C.; Zhuang, Z.; Yuan, R.-Y.; Zheng, Q.-B.; Zhou, P.-P.; Li, J.-P.; Chen, X.-C.; Zhang, X.; Yu, X.-H.; Kong, X.-W.; Zhu, Q.-Y.; Xu, M.; Zhong, N.-S.; Zeng, Y.-X.; Feng, G.-K.; Ke, C.-W.; Zhao, J.-C.; Zeng, M.-S.
10.1101/2020.11.03.366138 — microbiology — Posted on 2020-11-03
3791 Identification of Cross-Reactive CD8+ T Cell Receptors with High Functional Avidity to a SARS-CoV-2 Immunodominant Epitope and Its Natural Mutant Variants
Hu, C.; Shen, M.; Han, X.; Chen, Q.; Li, L.; Chen, S.; Zhang, J.; Gao, F.; Wang, W.; Wang, Y.; Li, T.; Li, S.; Huang, J.; Wang, J.; Zhu, J.; Chen, D.; Wu, Q.; Tao, K.; Pang, D.; Jin, A.
10.1101/2020.11.02.364729 — immunology — Posted on 2020-11-03
3792 Action enhances predicted touch
Thomas, E. R.; Yon, D.; de Lange, F. P.; Press, C.
10.1101/2020.03.26.007559 — neuroscience — Posted on 2020-11-03
3793 Classical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer
Patel, A. S.; Yoo, S.; Kong, R.; Sato, T.; Sinha, A.; Bao, L.; Fridrikh, M.; Emoto, K.; Nudelman, G.; Powell, C. A.; Beasley, M. B.; Zhu, J.; Watanabe, H.
10.1101/852939 — cancer biology — Posted on 2020-11-03
3795 Cross-Platform Validation of Neurotransmitter Release Impairments in Schizophrenia Patient-Derived NRXN1-Mutant Neurons
Pak, C.; Danko, T.; Mirabella, V. R.; Wang, J.; Zhang, X.; Ward, T.; Grieder, S.; Vangipuram, M.; Huang, Y.-W. A.; Liu, Y.; Jin, K.; Dexheimer, P.; Bardes, E.; Mitelpunkt, A.; Ma, J.; McLachlan, M.; Moore, J. C.; Urban, A. E.; Dage, J. L.; Swanson, B. J.; Aronow, B. J.; Pang, Z. P.; Levinson, D. F.; Wernig, M.; Sudhof, T. C.
10.1101/2020.11.03.366617 — neuroscience — Posted on 2020-11-03
3796 Alcohol dependence activates ventral tegmental area projections to central amygdala in male mice and rats
Avegno, E. M.; Kasten, C. R.; Snyder, W. B.; Kelley, L. K.; Lobell, T. D.; Templeton, T. J.; Constans, M.; Wills, T. A.; Middleton, J. W.; Gilpin, N. W.
10.1101/2020.11.02.365445 — neuroscience — Posted on 2020-11-03
3797 Assessing uncertainty in connective field estimations from resting state fMRI activity
Invernizzi, A.; Gravel, N. G.; Haak, K. V.; Renken, R. J.; Cornelissen, F. W.
10.1101/2020.11.02.365452 — neuroscience — Posted on 2020-11-03
3798 eNOS-dependent S-nitrosylation of the NF-κB subunit p65 has neuroprotective effects
Caviedes, A.; Maturana, B.; Corvalan, K.; Engler, A.; Gordillo, F.; Varas-Godoy, M.; Smalla, K.-H.; Batiz, L. F.; Lafourcade, C. A.; Kaehne, T.; Wyneken, U.
10.1101/2020.02.04.932772 — neuroscience — Posted on 2020-11-03
3799 Directed evolution for improved total secretory protein production in Escherichia coli
Gonzalez-Perez, D.; Ratcliffe, J.; Tan, S. K.; Wong, M. C. M.; Yee, Y. P.; Nyabadza, N.; Xu, J.-H.; Wong, T. S.; Tee, K. L.
10.1101/2020.11.03.366773 — synthetic biology — Posted on 2020-11-03
3800 Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4
Hoeksema, M. A.; Shen, Z.; Holtman, I. R.; Zheng, A.; Spann, N.; Cobo, I.; Gymrek, M.; Glass, C. K.
10.1101/2020.11.02.365742 — genomics — Posted on 2020-11-03
3802 A global indicator of utilised wildlife populations: regional trends and the impact of management
McRae, L.; Freeman, R.; Geldmann, J.; Moss, G. B.; Kjaer-Hansen, L.; Burgess, N. D.
10.1101/2020.11.02.365031 — ecology — Posted on 2020-11-03
3807 Computation of the electroencephalogram (EEG) from network models of point neurons
Martinez Canada, P.; Ness, T. V.; Einevoll, G. T.; Fellin, T.; Panzeri, S.
10.1101/2020.11.02.364802 — neuroscience — Posted on 2020-11-03
3810 Signature morpho-electric, transcriptomic, and dendritic properties of extratelencephalic-projecting human layer 5 neocortical pyramidal neurons
Kalmbach, B.; Hodge, R.; Jorstad, N.; Owen, S.; Bakken, T.; de Frates, R.; Yanny, A. M.; Dalley, R.; Graybuck, L.; Daigle, T.; Radaelli, C.; Mallory, M.; McGraw, M.; Dee, N.; Nicovich, P.; Keene, D.; Gwinn, R.; Silbergeld, D.; Cobbs, C.; Ojemann, J.; Ko, A.; Patel, A.; Ellenbogen, R.; Sorensen, S.; Smith, K.; Zeng, H.; Tasic, B.; Koch, C.; Lein, E.; Ting, J.
10.1101/2020.11.02.365080 — neuroscience — Posted on 2020-11-03
3811 Associations between Early Midlife Lifestyle Behaviors, Young Adult Cognitive Reserve and Advanced Predicted Brain Age in Late Midlife
Franz, C. E.; Hatton, S. N.; Elman, J. A.; Warren, T.; Gillespie, N. A.; Whitsel, N. A.; Puckett, O. K.; Dale, A. M.; Eyler, L. T.; Fennema-Notestine, C.; Hagler, D. J.; Hauger, R. L.; McKenzie, R.; Neale, M. C.; Panizzon, M. S.; Pearce, R. C.; Reynolds, C. R.; Sanderson-Cimino, M.; Toomey, R.; Tu, X.; Xian, H.; Lyons, M. J.; Kremen, W.
10.1101/2020.11.02.362780 — neuroscience — Posted on 2020-11-03
3813 Learning to live with Dale's principle: ANNs with separate excitatory and inhibitory units
Cornford, J.; Kalajdzievski, D.; Leite, M.; Lamarquette, A.; Kullmann, D. M.; Richards, B. A.
10.1101/2020.11.02.364968 — neuroscience — Posted on 2020-11-03
3815 Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila
Gericke, O.; Fowler, R. M.; Heskes, A. M.; Bayly, M.; Semple, S. J.; Ndi, C. P.; Staerk, D.; Loland, C. J.; Murphy, D. J.; Buirchell, B. J.; Moller, B. L.
10.1101/2020.11.02.364471 — plant biology — Posted on 2020-11-03
3816 Machine learning enabled phenotyping for GWAS and TWAS of WUE traits in 869 field-grown sorghum accessions
Ferguson, J.; Fernandes, S.; Monier, B.; Miller, N. D.; Allan, D.; Dmitrieva, A.; Schmuker, P.; Lozano, R.; Valluru, R.; Buckler, E. S.; Gore, M. A.; Brown, P.; Spalding, E. P.; Leakey, A.
10.1101/2020.11.02.365213 — plant biology — Posted on 2020-11-03
3817 RESTORING CONNEXIN-36 FUNCTION IN DIABETOGENIC ENVIRONMENTS PRECLUDES MOUSE AND HUMAN ISLET DYSFUNCTION
St Clair, J. R.; Westacott, M. J.; Farnsworth, N. L.; Kravets, V.; Schleicher, W. E.; Miranda, J. G.; Heintz, A.; Ludin, N. W. F.; Benninger, R. K.
10.1101/2020.11.03.366179 — biophysics — Posted on 2020-11-03
3818 Runcer-Necromancer: A Method To Rescue Data From An Interrupted Run On MGISEQ-2000
Pavlova, A.; Belova, V.; Afasizhev, R.; Bulusheva, I.; Rebrikov, D.; Korostin, D.
10.1101/2020.11.02.364588 — bioinformatics — Posted on 2020-11-03
3819 Immunopeptidomics for Dummies: Detailed Experimental Protocols and Rapid, User-Friendly Visualization of MHC I and II Ligand Datasets with MhcVizPipe
Sirois, I.; Caron, E.; Kovalchik, K. A.; Wessling, L.; Saab, F.; Ma, Q.; Despault, J.; Kubiniok, P.; Hamelin, D.; Faridi, P.; Li, C.; Purcell, A. W.; Tognetti, M.; Reiter, L.; Bruderer, R.; Lanoix, J.; Bonneil, E.; Courcelles, M.; Thibault, P.
10.1101/2020.11.02.360958 — bioinformatics — Posted on 2020-11-03
3825 Novel incursion of a highly pathogenic avian influenza subtype H5N8 virus in the Netherlands, October 2020
Beerens, N.; Heutink, R.; Harders, F.; Roose, M.; Pritz-Verschuren, S.; Germeraad, E.; Engelsma, M.
10.1101/2020.11.03.361634 — microbiology — Posted on 2020-11-03
3826 COVID-19 cytokines and the hyperactive immune response: Synergism of TNF-α and IFN-γ in triggering inflammation, tissue damage, and death
Karki, R.; Sharma, B. R.; Tuladhar, S.; Williams, E. P.; Zalduondo, L.; Samir, P.; Zheng, M.; Sundaram, B.; Banoth, B.; Malireddi, R. K. S.; Schreiner, P.; Neale, G.; Vogel, P.; Webby, R.; Jonsson, C. B.; Kanneganti, T.-D.
10.1101/2020.10.29.361048 — immunology — Posted on 2020-11-03
3829 The vesicular release probability sets the strength of individual Schaffer collateral synapses
Duerst, C. D.; Wiegert, J. S.; Schulze, C.; Helassa, N.; Torok, K.; Oertner, T. G.
10.1101/2020.08.02.232850 — neuroscience — Posted on 2020-11-03
3830 Kinetic model of small RNA-mediated regulation suggests that a small RNA can regulate co-transcriptionally
Reyer, M. A.; Chennakesavalu, S.; Heideman, E. M.; Ma, X.; Bujnowska, M.; Hong, L.; Dinner, A. R.; Vanderpool, C. K.; Fei, J.
10.1101/2020.11.03.365106 — biophysics — Posted on 2020-11-03
3831 Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
Schneider, M. M.; Scheidt, T.; Priddey, A. J.; Xu, C. K.; Hu, M.; Devenish, S. R. A.; Meisl, G.; Dobson, C. M.; Kosmoliaptsis, V.; Knowles, T. P. J.
10.1101/2020.09.14.296442 — biophysics — Posted on 2020-11-03
3832 Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis
Lizarrondo, J.; Klebl, D. P.; Niebling, S.; Abella, M.; Schroer, M. A.; Mertens, H. D. T.; Veith, K.; Svergun, D. I.; Skruzny, M.; Sobott, F.; Muench, S.; Garcia-Alai, M. M.
10.1101/2020.11.03.364851 — biophysics — Posted on 2020-11-03
3834 Selection on ancient variations drives the adaptive radiation of Metrosideros across the Hawaiian archipelago
Choi, J. Y.; Dai, X.; Peng, J. Z.; Rughani, P.; Hickey, S.; Harrington, E.; Juul, S.; Ayroles, J.; Purugganan, M.; Stacy, E.
10.1101/2020.11.03.354068 — evolutionary biology — Posted on 2020-11-03
3837 Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
Mainali, R.; Zabalwi, M.; Long, D.; Buechler, N.; Quillen, E.; Key, C.-C.; Zhu, X.; Parks, J.; Furdui, C.; Stacpoole, P.; Martinez, J.; McCall, C. E.; Quinn, M. A.
10.1101/2020.06.09.142430 — immunology — Posted on 2020-11-03
3838 Citric Acid Water as an Alternative to Water Restriction for High-Yield Mouse Behavior
Urai, A. E.; Aguillon-Rodriguez, V.; Laranjeira, I.; Cazettes, F.; The International Brain Laboratory, ; Mainen, Z. F.; Churchland, A. K.
10.1101/2020.03.02.973016 — neuroscience — Posted on 2020-11-03
3839 A fine-tuned interplay of three A. thaliana UDP glucosyltransferases orchestrates salicylic acid homeostasis
Bauer, S.; Georgii, E.; Lange, B.; Maksym, R. P.; Janowski, R.; Geist, B.; Schaeffner, A. R.
10.1101/2020.11.02.365221 — plant biology — Posted on 2020-11-03
3841 Oxylipin metabolism is controlled by mitochondrial b-oxidation during bacterial inflammation.
Misheva, M.; Kotzamanis, K.; Davies, L.; Tyrrell, V.; Rodrigues, P.; Benavides, G.; Christine, H.; Murphy, R.; Kennedy, P.; Taylor, P.; Rosas, M.; Jones, S.; Deshpande, S.; Andrews, R.; Czubala, M.; Gurney, M.; Aldrovandi, M.; Meckelmann, S.; Ghazal, P.; Darley-Usmar, V.; White, D.; O'Donnell, V.
10.1101/2020.08.17.252007 — biochemistry — Posted on 2020-11-03
3845 Simvastatin Therapy Attenuates Memory Deficits that Associate to Brain Monocyte Infiltration in Chronic Hypercholesterolemic ApoE-/- Mice
Don-Doncow, N.; Matthes, F.; Matuskova, H.; Rattik, S.; Vanherle, L.; Kragh Petersen, S.; Hartlova, A.; Meissner, A.
10.1101/2020.05.15.098236 — physiology — Posted on 2020-11-03
3846 Loss of the RNA helicase Dhx15 impairs endothelial energy metabolism, lymphatic drainage and tumor metastasis in mice
Ribera, J.; Portoles, I.; Cordoba-Jover, B.; Rodriguez-Vita, J.; Casals, G.; Gonzalez-de la Presa, B.; Graupera, M.; Soria, G.; Tudela, R.; Esteve-Codina, A.; Espadas, G.; Sabido, E.; Jimenez, W.; Sessa, W. C.; Morales-Ruiz, M.
10.1101/2020.11.03.366286 — cell biology — Posted on 2020-11-03
3847 GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers
Bianco, G.; Coto Llerena, M.; Gallon, J.; Taha-Mehlitz, S.; Kancherla, V.; Konantz, M.; Srivatsa, S.; Montazeri, H.; Panebianco, F.; De Menna, M.; Paradiso, V.; Ercan, C.; Dahmani, A.; Montaudon, E.; Beerenwinkel, N.; Kruithof-de Julio, M.; Terracciano, L.; Lengerke, C.; Bidard, F.-C.; Jeselsohn, R.; Marangoni, E.; Ng, C. K.; Piscuoglio, S.
10.1101/2020.05.18.101998 — cancer biology — Posted on 2020-11-03
3851 Fast-Bonito: A Faster Basecaller for Nanopore Sequencing
Xu, Z.; Mai, Y.; Liu, D.; He, W.; Lin, X.; Xu, C.; Zhang, L.; Meng, X.; Mafofo, J.; Zaher, W. A.; Li, Y.; Qiao, N.
10.1101/2020.10.08.318535 — bioinformatics — Posted on 2020-11-03
3853 Direct Quantification of in vivo Mutagenesis and Carcinogenesis Using Duplex Sequencing
Valentine, C. C.; Young, R. R.; Fielden, M. R.; Kulkarni, R.; Williams, L. N.; Li, T.; Minocherhomji, S.; Salk, J. J.
10.1101/2020.06.28.176685 — genomics — Posted on 2020-11-03
3854 The Pleistocene species pump past its prime: evidence from European butterfly sister species
Ebdon, S.; Laetsch, D. R.; Dapporto, L.; Hayward, A.; Ritchie, M. G.; Dinca, V.; Vila, R.; Lohse, K.
10.1101/2020.09.04.282962 — evolutionary biology — Posted on 2020-11-03
3855 Differential effects of prediction and adaptation along the cortical hierarchy during deviance processing
Schlossmacher, I.; Dilly, J.; Protmann, I.; Hofmann, D.; Dellert, T.; Roth-Paysen, M.-L.; Moeck, R.; Bruchmann, M.; Straube, T.
10.1101/2020.10.19.339234 — neuroscience — Posted on 2020-11-03
3856 LincRNA sequences are biased to counteract translation
Brümmer, A.; Dreos, R.; Marques, A. C.; Bergmann, S.
10.1101/737890 — genomics — Posted on 2020-11-03
3857 More rule than exception: Parallel evidence of ancient migrations in grammars and genomes of Finno-Ugric speakers
Santos, P.; Gonzalez-Fortes, G.; Trucchi, E.; Ceolin, A.; Cordoni, G.; Guardiano, C.; Longobardi, G.; Barbujani, G.
10.1101/2020.11.02.364521 — genomics — Posted on 2020-11-03
3858 Experimental evolution of adaptive divergence under varying degrees of gene flow
Tusso, S.; Nieuwenhuis, B. P. S.; Weissensteiner, B.; Immler, S.; Wolf, J. B. W.
10.1101/2020.11.02.364695 — evolutionary biology — Posted on 2020-11-03
3859 Extensive MET alterations confer clinical response to MET inhibitors in gliomas
Zhao, Z.; Chen, J.; Bao, Z.; Chai, R.; Zhang, K.-n.; Wu, L.; Liu, H.; Mu, Q.; Hu, H.; Zeng, F.; Wang, Z.; Li, G.; Chang, Y.; Wang, Q.; Wu, F.; Zhang, Y.; Liu, Y.; Zhang, W.; Kang, C.; Wang, J.; Tao, R.; Wang, Q.; Jiang, T.
10.1101/2020.11.02.364711 — neuroscience — Posted on 2020-11-03
3860 crispr2vec: Machine Learning Model Predicts Off-Target Cuts of CRISPR systems
Basu Trivedi, T.; Boger, R.; Kamath, G.; Evangelopoulos, G.; Cate, J.; Doudna, J.; Hidary, J.
10.1101/2020.10.28.359885 — synthetic biology — Posted on 2020-11-03
3862 A Two-Step Bioreactor for Lung Recellularization
Young, B. M.; Antczak, L.-A. M.; Shankar, K.; Heise, R. L.
10.1101/2020.11.02.360792 — bioengineering — Posted on 2020-11-02
3865 Liquid chalk is an antiseptic against SARS-CoV-2 and influenza A respiratory viruses
McAuley, J. L.; Deerain, J. M.; Hammersla, W.; Aktepe, T. E.; Purcell, D. J. F.; Mackenzie, J.
10.1101/2020.11.02.364661 — microbiology — Posted on 2020-11-02
3867 Extensive MET alterations confer clinical response to MET inhibitors in gliomas
Zhao, Z.; Chen, J.; Bao, Z.; Chai, R.; Zhang, K.-n.; Wu, L.; Liu, H.; Mu, Q.; Hu, H.; Zeng, F.; Wang, Z.; Li, G.; Chang, Y.; Wang, Q.; Wu, F.; Zhang, Y.; Liu, Y.; Zhang, W.; Kang, C.; Wang, J.; Tao, R.; Wang, Q.; Jiang, T.
10.1101/2020.11.02.364711 — neuroscience — Posted on 2020-11-02
3871 Engineered Red Blood Cells Carrying PCSK9 Inhibitors Persistently Lower LDL and Prevent Obesity
Deshycka, R.; Sudaryo, V.; Huang, N.-J.; Xie, Y.; Smeding, L. Y.; Choi, M. K.; Ploegh, H.; Lodish, H.; Pishesha, N.
10.1101/2020.11.02.364620 — bioengineering — Posted on 2020-11-02
3874 An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Chawla, M.; Mukherjee, T.; Deka, A.; Chatterjee, B.; Sarkar, U. A.; Singh, A. K.; Kedia, S.; Banoth, B.; Biswas, S. K.; Ahuja, V.; Basak, S.
10.1101/2020.11.02.365890 — immunology — Posted on 2020-11-02
3875 Focus-tunable microscope for imaging small neuronal processes in freely moving animals
Bagramyan, A.; Tabourin, L.; Rastqar, A.; Karimi, N.; Bretzner, F.; Galstian, T.
10.1101/2020.10.31.363507 — neuroscience — Posted on 2020-11-02
3876 YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER
Lefort, S.; El-Naggar, A.; Tan, S.; Colborne, S.; Negri, G. L.; Pellacani, D.; Hirst, M.; Gusterson, B.; Morin, G. B.; Sorensen, P. H.; Eaves, C. J.
10.1101/372524 — cancer biology — Posted on 2020-11-02
3877 Lipogenesis and innate immunity in hepatocellular carcinoma cells reprogrammed by an isoenzyme switch of hexokinases
Perrin-Cocon, L.; Vidalain, P.-O.; Jacquemin, C.; Aublin-Gex, A.; Olmstead, K.; Panthu, B.; Rautureau, G. J. P.; Andre, P.; Nyczka, P.; Hutt, M.-T.; Amoedo, N.; Rossignol, R.; Filipp, F. V.; Lotteau, V.; Diaz, O.
10.1101/2020.03.13.973321 — cancer biology — Posted on 2020-11-02
3880 Trade-offs between risks of predation and starvation in larvae make the shelf break an optimal spawning location for Atlantic Bluefin tuna
Shropshire, T. A.; Morey, S. L.; Chassignet, E. P.; Karnauskas, M.; Coles, V. J.; Malca, E.; Laiz-Carrion, R.; Fiksen, O.; Reglero, P.; Shiroza, A.; Maria Quintanilla Hervas, J.; Gerard, T.; Lamkin, J.; Stukel, M. R.
10.1101/2020.11.01.363465 — ecology — Posted on 2020-11-02
3882 DNAJB12 and Hsp70 Facilitate the Conformation Specific Degradation of Arrested N1303K-CFTR Intermediates by ERQC-Autophagy
He, L.; Kennedy, A. S.; Houck, S.; Aleksandrov, A. A.; Quinney, N. L.; Gentzsch, M.; Cholon, D.; Randell, S. H.; Ren, H. Y.; Cyr, D. M.
10.1101/2020.10.28.358580 — cell biology — Posted on 2020-11-02
3883 Breastmilk-promoted bifidobacteria produce aromatic lactic acids in the infant gut
Laursen, M. F.; Sakanaka, M.; von Burg, N.; Mörbe, U.; Andersen, D.; Moll, J. M.; Pekmez, C. T.; Rivollier, A.; Michaelsen, K. F.; Molgaard, C.; Lind, M. V.; Dragsted, L. O.; Katayama, T.; Frandsen, H. L.; Vinggaard, A. M.; Bahl, M. I.; Brix, S.; Agace, W.; Licht, T. R.; Roager, H. M.
10.1101/2020.01.22.914994 — microbiology — Posted on 2020-11-02
3884 Microbiota functional activity biosensors for characterizing nutrient utilization in vivo
Wesener, D. A.; Beller, Z. W.; Peters, S. L.; Rajabi, A.; Dimartino, G.; Giannone, R. J.; Hettich, R. L.; Gordon, J. I.
10.1101/2020.11.02.362798 — microbiology — Posted on 2020-11-02
3885 Neutrophils encompass a regulatory subset suppressing T cells in apparently healthy cattle and mice
Rambault, M.; Doz-Deblauwe, E.; Le Vern, Y.; Carreras, F.; Cunha, P.; Germon, P.; Rainard, P.; Winter, N.; Remot, A.
10.1101/2020.11.02.364885 — immunology — Posted on 2020-11-02
3888 Timing of readiness potentials reflect a decision-making process in the human brain
Lui, K. K.; Nunez, M. D.; Cassidy, J. M.; Vandekerckhove, J.; Cramer, S. C.; Srinivasan, R.
10.1101/338806 — neuroscience — Posted on 2020-11-02
3889 Single-molecule studies of conformational states and dynamics in the ABC importer OpuA
Tassis, K.; Vietrov, R.; Koning, M. d.; de Boer, M.; Gouridis, G.; Cordes, T.
10.1101/2020.08.07.241463 — biophysics — Posted on 2020-11-02
3893 Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes
Zhu, X.; Boulet, A.; Buckley, K. M.; Phillips, C. B.; Gammon, M. G.; Oldfather, L. E.; Moore, S. A.; Leary, S. C.; Cobine, P. A.
10.1101/2020.11.02.365692 — evolutionary biology — Posted on 2020-11-02
3894 Single cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination
Mayere, C.; Neirijnck, Y.; Sararols, P.; Rands, C.; Stevant, I.; Kühne, F.; Chassot, A.-A.; Chaboissier, M.-C.; Dermitzakis, E.; Nef, S.
10.1101/747279 — developmental biology — Posted on 2020-11-02
3896 Reduced ech-6 Expression Attenuates Fat-induced Premature Aging in C. elegans
Liu, Y. J.; Gao, A. W.; Smith, R. L.; Janssens, G. E.; Panneman, D. M.; Jongejan, A.; van Weeghel, M.; Vaz, F. M.; Silvestrini, M. J.; Lapierre, L. R.; MacInnes, A. W.; Houtkooper, R. H.
10.1101/2020.11.02.364760 — cell biology — Posted on 2020-11-02
3897 Creld2 function during unfolded protein response is essential for liver metabolism homeostasis
Kern, P.; Balzer, N. R.; Bender, F.; Frolov, A.; Wunderling, K.; Sowa, J.-P.; Bonaguro, L.; Ulas, T.; Thiele, C.; Schultze, J. L.; Canbay, A.; Bauer, R.; Mass, E.
10.1101/2020.01.28.923136 — molecular biology — Posted on 2020-11-02
3898 Production of nonulosonic acids in the extracellular polymeric substances of Candidatus Accumulibacter phosphatis
Tomas-Martinez, S.; Kleikamp, H. B. C.; Neu, T. R.; Pabst, M.; Weissbrodt, D. G.; van Loosdrecht, M. C. M.; Lin, Y.
10.1101/2020.11.02.365007 — microbiology — Posted on 2020-11-02
3902 Developmental effects of oxytocin neurons on social affiliation and processing of social information
Nunes, A. R.; Gliksberg, M.; Varela, S. A. M.; Teles, M.; Wircer, E.; Blechman, J.; Petri, G.; Levkowitz, G.; Oliveira, R. F.
10.1101/2020.10.08.330993 — neuroscience — Posted on 2020-11-02
3903 Imaging stable isotope labelling kinetics (iSILK) for following spatial Aβ plaque aggregation dynamics in evolving Alzheimers disease pathology
Michno, W.; Stringer, K. M.; Enzlein, T.; Passarelli, M.; Escrig, S.; Blennow, K.; Zetterberg, H.; Meibom, A.; Hopf, C.; Edwards, F. A.; Hanrieder, J.
10.1101/2020.10.12.335828 — neuroscience — Posted on 2020-11-02
3904 RTP801 REGULATES MOTOR CORTEX SYNAPTIC TRANSMISSION AND LEARNING
Perez-Sisques, L.; Martin-Flores, N.; Masana, M.; Solana, J.; Llobet, A.; Romani-Aumedes, J.; Canal, M.; Campoy, G.; Garcia, E.; Sanchez, N.; Fernandez, S.; Gilbert, J. P.; Rodriguez, M. J.; Man, H.; Feinstein, E.; Williamson, D.; Soto, D.; Gasull, X.; Alberch, J.; Malagelada, C.
10.1101/2020.10.15.340851 — neuroscience — Posted on 2020-11-02
3905 Transient Maternal IL-6 boosts glutamatergic synapses and disrupts hippocampal connectivity in the offspring
Mirabella, F.; Desiato, G.; Mancinelli, S.; Fossati, G.; Rasile, M.; Morini, R.; Markicevic, M.; Grimm, C.; amegandjin, C.; Termanini, A.; Peano, C.; Kunderfranco, P.; DiCristo, G.; Zerbi, V.; Lodato, S.; Menna, E.; Matteoli, M.; Pozzi, D.
10.1101/2020.11.02.364356 — neuroscience — Posted on 2020-11-02
3907 ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1
Statzer, C.; Venz, R.; Bland, M.; Robida-Stubbs, S.; Meng, J.; Patel, K.; Emsley, R.; Petrovic, D.; Liu, P.; Morantte, I.; Haynes, C.; Filipovic, M.; Mair, W. B.; Longchamp, A.; Blackwell, T. K.; Ewald, C. Y.
10.1101/2020.11.02.364703 — physiology — Posted on 2020-11-02
3908 NOVEL NUCLEAR ROLE OF HDAC6 IN PROGNOSIS AND THERAPEUTIC TARGET FOR COLORECTAL CANCER
Garcia-Dominguez, D. J.; Hontecillas-Prieto, L.; Kaliszczak, M.; He, M.; Burguillos, M.; El Bekay, R.; Abdul-Salam, V. B.; Combiz, K.; Shah, K.; O'Neill, k.; de Alava, E.; Silver, A.; Syed, N.; Aboagye, E. O.; Hajji, N.
10.1101/2020.11.02.356121 — cancer biology — Posted on 2020-11-02
3909 Multi-modal Nonlinear Optical and Thermal Imaging Platform for Label-Free Characterization of Biological Tissue
Adams, W. R.; Mehl, B.; Lieser, E.; Wang, M.; Patton, S.; Throckmorton, G. A.; Jenkins, J. L.; Ford, J. B.; Gautam, R.; Brooker, J.; Jansen, E. D.; Mahadevan-Jansen, A.
10.1101/2020.04.06.023820 — biophysics — Posted on 2020-11-02
3910 Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics
Maniou, E.; Staddon, M.; Marshall, A.; Greene, N.; Copp, A.; Banerjee, S.; Galea, G.
10.1101/2020.11.02.364513 — biophysics — Posted on 2020-11-02
3914 Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition interface
Bayne, R. A.; Jayachandran, U.; Kasprowicz, A.; Bresson, S.; Tollervey, D.; Wallace, E. W. J.; Cook, A. G.
10.1101/2020.10.22.350314 — biochemistry — Posted on 2020-11-02
3918 Relative time constraints improve molecular dating
Szollosi, G. J.; Hoehna, S.; Williams, T. A.; Schrempf, D.; Daubin, V.; Boussau, B.
10.1101/2020.10.17.343889 — evolutionary biology — Posted on 2020-11-02
3919 Correction of a Factor VIII genomic inversion with designer-recombinases
Lansing, F.; Mukhametzyanova, L.; Rojo-Romanos, T.; Iwasawa, K.; Kimura, M.; Paszkowski-Rogacz, M.; Karpinski, J.; Grass, T.; Sonntag, J.; Schneider, P. M.; Günes, C.; Hoersten, J.; Schmitt, L. T.; Rodriguez-Muela, N.; Knöfler, R.; Takebe, T.; Buchholz, F.
10.1101/2020.11.02.328013 — molecular biology — Posted on 2020-11-02
3920 Common transcriptional programme of liver fibrosis in mouse genetic models and humans
Blagotinsek Cokan, K.; Urlep, Z.; Moskon, M.; Mraz, M.; Kong, X. Y.; Eskild, W.; Rozman, D.; Juvan, P.; Rezen, T.
10.1101/2020.11.02.364901 — molecular biology — Posted on 2020-11-02
3921 Homeodomain protein 1 is an essential regulator of gene expression during sexual differentiation of malaria parasites
Campelo Morillo, R.; Tong, X.; Xie, W.; Lenz, T.; Batugedara, G.; Tabassum, N.; Orchard, L. M.; Daher, W.; Patel, D.; Noble, W. S.; Llinas, M.; Le Roch, K. G.; Kafsack, B. F. C.
10.1101/2020.10.26.352583 — microbiology — Posted on 2020-11-02
3922 IL-12 signaling promotes TET2-mediated DNA demethylation during CD8 T cell effector differentiation
Zebley, C.; Abdelsamed, H.; Ghoneim, H.; Alli, S.; Haydar, D.; Harris, T.; Mcgargill, M.; Krenciute, G.; Youngblood, B.
10.1101/2020.11.02.365148 — immunology — Posted on 2020-11-02
3923 An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Chawla, M.; Mukherjee, T.; Deka, A.; Chatterjee, B.; Sarkar, U. A.; Singh, A. K.; Kedia, S.; Banoth, B.; Biswas, S. K.; Ahuja, V.; Basak, S.
10.1101/2020.11.02.365890 — immunology — Posted on 2020-11-02
3924 NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers
Ong, C. E. B.; Patchett, A. L.; Darby, J. M.; Chen, J.; Liu, G.-S.; Lyons, A. B.; Woods, G. M.; Flies, A. S.
10.1101/2020.09.06.274720 — immunology — Posted on 2020-11-02
3925 The G protein-Coupled Metabotropic Glutamate Receptor 1 controls neuronal macroautophagy
Donoso, M.; Speranza, L.; Kalinowska, M.; Castillo, C.; De Sanctis, C.; Francesconi, A.
10.1101/2020.11.02.365783 — neuroscience — Posted on 2020-11-02
3926 Control of neurogenic competence in mammalian hypothalamic tanycytes.
Yoo, S.; Kim, J.; Lyu, P.; Hoang, T.; Ma, A.; Trinh, V.; Dai, W.; Jiang, L.; Leavey, P.; Won, J.-K.; Park, S.-H.; Qian, J.; Brown, S. P.; Blackshaw, S.
10.1101/2020.11.02.359992 — neuroscience — Posted on 2020-11-02
3929 The timing and impact of psychiatric, cognitive and motor manifestations of Huntington's disease
McAllister, B.; Gusella, J. F.; Landwehrmeyer, G. B.; Lee, J.-M.; MacDonald, M. E.; Orth, M.; Rosser, A. E.; Williams, N. M.; REGISTRY Investigators of the European Huntington's disease network, ; Holmans, P.; Jones, L.; Massey, T. H.
10.1101/2020.05.26.116798 — neuroscience — Posted on 2020-11-02
3930 Loss of a plant receptor kinase recruits beneficial rhizosphere-associated Pseudomonas
Song, Y.; Wilson, A. J.; Zhang, X.-C.; Thoms, D.; Sohrabi, R.; Song, S.; Geissmann, Q.; Liu, Y.; Walgren, L.; He, S. Y.; Haney, C. H.
10.1101/2020.11.02.364109 — plant biology — Posted on 2020-11-02
3931 Ivermectin reduces coronavirus infection in vivo: a mouse experimental model
Arevalo, A. P.; Pagotto, R.; Porfido, J.; Daghero, H.; Segovia, M.; Yamasaki, K.; Varela, B.; Hill, M.; Verdes, J. M.; Duhalde Vega, M.; Bollati-Fogolin, M.; Crispo, M.
10.1101/2020.11.02.363242 — pathology — Posted on 2020-11-02
3932 The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor
Legge, D.; Ling, L.; Moriarty, W.; Lee, D.; Szemes, M.; Zahed, A.; Panousopoulus, L.; Chung, W. Y.; Aghabi, Y.; Barrett, J.; Williams, R.; Pritchard-Jones, K.; Malik, K.; Oltean, S.; Brown, K. W.
10.1101/2020.11.02.364570 — cancer biology — Posted on 2020-11-02
3933 Adipose Triglyceride Lipase is needed for homeostatic control of Sterol Element-Binding Protein-1c driven hepatic lipogenesis
Wieser, B. I.; Pena de la Sancha, P.; Schauer, S.; Reicher, H.; Sattler, W.; Breinbauer, R.; Schweiger, M.; Espenshade, P. J.; Zechner, R.; Hoefler, G.; Vesely, P. W.
10.1101/2020.11.02.363440 — biochemistry — Posted on 2020-11-02
3940 Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo
Tan, C. Y.; Mahbub, S. B.; Campugan, C. A.; Campbell, J. M.; Habibalahi, A.; Chow, D. J. X.; Mustafa, S.; Goldys, E. M.; Dunning, K. R.
10.1101/2020.11.01.364133 — cell biology — Posted on 2020-11-02
3943 Small-scale commercial chicken production: A risky business for farmers in the Mekong Delta of Vietnam
Truong, B. D.; Van Cuong, N.; Phu, D. H.; Dung, N. T. T.; Kiet, B. T.; Rushton, J.; Carrique-Mas, J.
10.1101/2020.11.02.364281 — microbiology — Posted on 2020-11-02
3944 Robust SARS-CoV-2-specific T-cell immunity is maintained at 6 months following primary infection
Zuo, J.; Dowell, A.; Pearce, H.; Verma, K.; Long, H.; Begum, J.; Aiano, F.; Amin-Chowdhury, Z.; Hallis, B.; Stapley, L.; Borrow, R.; Linley, E.; Ahmad, S.; Parker, B.; Horsley, A.; Amirthalingam, G.; Brown, K.; Ramsay, M. E.; Ladhani, S.; Moss, P.
10.1101/2020.11.01.362319 — immunology — Posted on 2020-11-02
3946 Beyond linearity in neuroimaging: Capturing nonlinear relationships with application to longitudinal studies
Chen, G.; Nash, T. A.; Reding, K. M.; Kohn, P. D.; Wei, S.-M.; Gregory, M. D.; Eisenberg, D. P.; Cox, R. W.; Berman, K. F.; Kippenhan, J. S.
10.1101/2020.11.01.363838 — neuroscience — Posted on 2020-11-02
3947 A molecular calcium integrator reveals a striatal cell-type driving aversion
Kim, C. K.; Sanchez, M. I.; Hoerbelt, P.; Fenno, L. E.; Malenka, R. C.; Deisseroth, K.; Ting, A. Y.
10.1101/2020.11.01.364174 — neuroscience — Posted on 2020-11-02
3949 Functional brain network topology across the menstrual cycle is sex hormone dependent and correlates with the individual well-being
Liparoti, M.; Troisi Lopez, E.; Sarno, L.; Rucco, R.; Minino, R.; Pesoli, M.; Perruolo, G.; Formisano, P.; Lucidi, F.; Sorrentino, G.; Sorrentino, P.
10.1101/2020.11.01.363937 — neuroscience — Posted on 2020-11-02
3950 Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming
Tawfik, B.; Martins, J. S.; Houy, S.; Imig, C.; Pinheiro, P. S.; Wojcik, S. M.; Brose, N.; Cooper, B. H.; Sorensen, J. B.
10.1101/2020.11.02.365478 — neuroscience — Posted on 2020-11-02
3953 Bacterially produced small molecules stimulate diatom growth
Sittmann, J.; Bae, M.; Mevers, E.; Li, M.; Quinn, A.; Sriram, G.; Clardy, J.; Liu, Z.
10.1101/2020.11.02.365239 — plant biology — Posted on 2020-11-02
3954 Canopy micrometeorology monitoring in diverse climates innovatively improves the evaluation heat-induced sterility of rice under climate change
Yoshimoto, M.; Fukuoka, M.; Tsujimoto, Y.; Matsui, T.; Kobayasi, K.; Saito, K.; van Oort, P. A. J.; Inusah, B. I. Y.; Vijayalakshmi, C.; Vijayalakshmi, D.; Weerakoon, W. M. W.; Chandradasa, S.; Myint Daw, T. T.; Phyo Daw, Z. C.; Tian, X.; Lur, H.-S.; Yang, C.-M.; Tarpley, L.; Manigbas, N. L.; Hasegawa, T.
10.1101/2020.11.01.363143 — plant biology — Posted on 2020-11-02
3955 Rare instances of haploid inducer DNA in potato dihaploids and ploidy-dependent genome instability
Amundson, K. R.; Ordonez, B.; Santayana, M.; Nganga, M. L.; Henry, I. M.; Bonierbale, M.; Khan, A.; Tan, E. H.; Comai, L.
10.1101/2020.11.02.365601 — plant biology — Posted on 2020-11-02
3960 SATB2 induction of a neural crest mesenchyme-like program drives invasion and drug resistance in melanoma
Fazio, M.; van Rooijen, E.; Dang, M.; van de Hoek, G.; Ablain, J.; Mito, J. K.; Yang, S.; Thomas, A.; Michael, J.; Fabo, T.; Modhurima, R.; Pessina, P.; Kaufman, C. K.; Zhou, Y.; White, R. M.; Zon, L. I.
10.1101/2020.11.01.364406 — cancer biology — Posted on 2020-11-02
3964 OmicPioneer-sc: an integrated, interactive visualization environment for single-cell sequencing data
Weinstein, J. N.; Rohrdanz, M. N.; Stucky, M. T.; Melott, J. M.; Jun, M.; Mohanty, V.; Manyam, G. C.; Wakefield, C.; Chen, K.; Navin, N.; Ryan, M. C.; Akbani, R.; Broom, B. M.
10.1101/2020.10.31.363580 — bioinformatics — Posted on 2020-11-02
3966 Genetic diversity analysis of the D614G mutation in SARS-CoV-2
Felix, P. T.; Silva, E. D. A. B.; Venancio, D. B. R.; Ramos, R. d. S.
10.1101/2020.10.30.362954 — bioinformatics — Posted on 2020-11-02
3968 Temporal patterns in the evolutionary genetic distance of SARS-CoV-2 during the COVID-19 pandemic
Lou, J.; Zhao, S.; Cao, L.; Chen, Z.; Chan, R. W.; Chong, M. K.; Zee, B. C.; Chan, P. K.; Wang, M. H.
10.1101/2020.11.01.363739 — bioinformatics — Posted on 2020-11-02
3970 MetaPop: A pipeline for macro- and micro-diversity analyses and visualization of microbial and viral metagenome-derived populations
Gregory, A. C.; Gerhardt, K.; Zhong, Z.-P.; Bolduc, B.; Temperton, B.; Konstantinidis, K. T. C.; Sullivan, M. B.
10.1101/2020.11.01.363960 — bioinformatics — Posted on 2020-11-02
3974 In vivo optical metabolic imaging of long-chain fatty acid uptake in orthotopic models of triple negative breast cancer
Madonna, M. C.; Duer, J. E.; Lee, J. V.; Williams, J.; Avsaroglu, B.; Zhu, C.; Deutsch, R.; Wang, R.; Crouch, B.; Hirschey, M.; Goga, A.; Ramanujam, N.
10.1101/2020.11.02.365288 — bioengineering — Posted on 2020-11-02
3975 Bioassemblying Macro-Scale, Lumnized Airway Tubes of Defined Shape via Multi-Organoid Patterning and Fusion
Liu, Y.; Dabrowska, C.; Mavousian, A.; Strauss, B.; Meng, F.; Mazzaglia, C.; Ouaras, K.; Macintosh, C.; Terentjev, E. M.; Lee, J.-H.; Huang, Y. Y. S.
10.1101/2020.11.01.363705 — bioengineering — Posted on 2020-11-02
3976 Senotherapeutic peptide reduces skin biological age and improves skin health
Zonari, A.; Brace, L. E.; Alkatib, K.; Porto, W. F.; Foyt, D.; Guiang, M.; Cruz, E. A. O.; Marshall, B.; Salgueiro, W. G.; Inan, M. D.; Rahman, M.; Anupom, T.; Vanapalli, S.; Mori, M. A.; Franco, O. L.; Oliveira, C. R.; Boroni, M.; Carvalho, J. L.
10.1101/2020.10.30.362822 — bioengineering — Posted on 2020-11-02
3978 Climate warming weakens local adaptation
Bontrager, M.; Muir, C. D.; Mahony, C. R.; Gamble, D. E.; Germain, R. M.; Hargreaves, A. L.; Kleynhans, E. J.; Thompson, K. A.; Angert, A. L.
10.1101/2020.11.01.364349 — evolutionary biology — Posted on 2020-11-02
3980 Mosquitoes of the Maculipennis complex in Northern Italy
Calzolari, M.; Desiato, R.; Albieri, A.; Bellavia, V.; Bertola, M.; Bonilauri, P.; Callegari, E.; Canziani, S.; Lelli, D.; Mosca, A.; Mulatti, P.; Peletto, S.; Ravagnan, S.; Roberto, P.; Torri, D.; Pombi, M.; Di Luca, M.; Montarsi, F.
10.1101/2020.11.02.365262 — ecology — Posted on 2020-11-02
3982 Photocatalyst under visible light irradiation inactivates SARS-CoV-2 on an abiotic surface
Uema, M.; Yonemitsu, K.; Momose, Y.; Ishii, Y.; Tateda, K.; Inoue, T.; Asakura, H.
10.1101/2020.11.01.364364 — microbiology — Posted on 2020-11-02
3983 Rapid inactivation of SARS-CoV-2 with ozone water
Inagaki, H.; Saito, A.; Sudaryatma, P. E.; Sugiyama, H.; Okabayashi, T.; Fujimoto, S.
10.1101/2020.11.01.361766 — microbiology — Posted on 2020-11-02
3984 The effect of heat on SARS-CoV-2 viability and RNA integrity as determined by plaque assay, virus culture and real-time RT-PCR
Burton, J. E.; Love, H.; Richards, K.; Burton, C.; Summers, S.; Pitman, J.; Easterbrook, L.; Davies, K.; Spencer, P.; Killip, M. J.; Cane, P. A.; Bruce, C. B.; Roberts, A. D. G.
10.1101/2020.11.02.365015 — microbiology — Posted on 2020-11-02
3985 The SARS-CoV-2 RNA interactome
Lee, S.; Lee, Y.-s.; Choi, Y.; Son, A.; Park, Y.; Lee, K.-M.; Kim, J.; Kim, J.-S.; Kim, V. N.
10.1101/2020.11.02.364497 — microbiology — Posted on 2020-11-02
3986 Chemical signatures of human odour generate a unique neural code in the brain of Aedes aegypti mosquitoes
Zhao, Z.; Zung, J. L.; Kriete, A. L.; Iqbal, A.; Younger, M. A.; Matthews, B. J.; Merhof, D.; Thiberge, S.; Strauch, M.; McBride, C. S.
10.1101/2020.11.01.363861 — neuroscience — Posted on 2020-11-02
3987 Intact sensory processing but hampered conflict detection when stimulus input is task-irrelevant
Nuiten, S. A.; Canales-Johnson, A.; Beerendonk, L.; Nanuashvili, N.; Fahrenfort, J. J.; Bekinschtein, T.; van Gaal, S.
10.1101/2020.10.31.363192 — neuroscience — Posted on 2020-11-02
3988 Effects of external stimulation on psychedelic state neurodynamics
Mediano, P. A. M.; Rosas, F. E.; Timmermann, C.; Roseman, L.; Nutt, D. J.; Feilding, A.; Kaelen, M.; Kringelbach, M. L.; Barrett, A. B.; Seth, A. K.; Muthukumaraswamy, S.; Bor, D.; Carhart-Harris, R. L.
10.1101/2020.11.01.356071 — neuroscience — Posted on 2020-11-02
3990 Structural basis for repurpose and design of nucleoside drugs for treating COVID-19
Yin, W.; Luan, X.; Li, Z.; Xie, Y.; Zhou, Z.; Liu, J.; Gao, M.; Wang, X.; Zhou, F.; Wang, Q.; Wang, Q.; Shen, D.; Zhang, Y.; Tian, G.; Aisa, H. A.; Hu, T.; Wei, D.; Jiang, Y.; Xiao, G.; Jiang, H.; Zhang, L.; Yu, X.; Shen, J.; Zhang, S.; Xu, H. E.
10.1101/2020.11.01.363812 — biophysics — Posted on 2020-11-02
3997 SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes
Li, Y.; Renner, D.; Comar, C. E.; Whelan, J.; Reyes, H.; Cardenas-Diaz, F. L.; Truitt, R.; Tan, L. H.; Dong, B.; Alysandratose, K. D.; Huang, J.; Palmer, J. N.; Adappa, N. D.; Kohanski, M. A.; Kotton, D. N.; Silverman, R. H.; Yang, W.; Morrisey, E.; Cohen, N.; Weiss, S. R.
10.1101/2020.09.24.312553 — microbiology — Posted on 2020-11-02
3999 Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models
Li, X.; Lidsky, P.; Xiao, Y.; Wu, C.-T.; Garcia-Knight, M.; Yang, J.; Nakayama, T.; Nayak, J. V.; Jackson, P. K.; Andino, R.; Shu, X.
10.1101/2020.10.28.359042 — microbiology — Posted on 2020-11-02
4001 The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity
Bolouri, H.; Speake, C.; Skibinski, D.; Long, S. A.; Hocking, A. M.; Campbell, D. J.; Hamerman, J. A.; Malhotra, U.; Buckner, J. H.; BRI COVID-19 Research Team,
10.1101/2020.09.18.303420 — immunology — Posted on 2020-11-02
4002 Focus-tunable microscope for imaging small neuronal processes in freely moving animals
Bagramyan, A.; Tabourin, L.; Rastqar, A.; Karimi, N.; Bretzner, F.; Galstian, T.
10.1101/2020.10.31.363507 — neuroscience — Posted on 2020-11-02
4003 Differential alteration of plant functions by homologous fungal candidate effectors
Goncalves dos Santos, K. C.; Pelletier, G.; Seguin, A.; Guillemette, F.; Hawkes, J.; Desgagne-Penix, I.; Germain, H.
10.1101/2020.10.30.363010 — plant biology — Posted on 2020-11-02
4004 Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA.
Hamano, F.; Matoba, K.; Hashidate, T.; Suzuki, T.; Miura, K.; Hishikawa, D.; Harayama, T.; Yuki, K.; Kita, Y.; Noda, N. N.; Shimizu, T.; Shindou, H.
10.1101/2020.10.31.363515 — biochemistry — Posted on 2020-11-02
4006 Molecular basis of F-actin regulation and sarcomere assembly via myotilin
Kostan, J.; Pavsic, M.; Puz, V.; Schwarz, T. C.; Drepper, F.; Molt, S.; Graewert, M. A.; Schreiner, C.; Sajko, S.; van der Ven, P. F. M.; Svergun, D.; Warscheid, B.; Konrat, R.; Fuerst, D. O.; Lenarcic, B.; Djinovic-Carugo, K.
10.1101/2020.09.25.310029 — biochemistry — Posted on 2020-11-02
4008 CoDNaS-RNA: a database of Conformational Diversity in the Native State of RNA
Gonzalez Buitron, M.; Tunque Cahui, R. R.; Garcia Rios, E.; Hirsh, L.; Fornasari, M. S.; Parisi, G.; Palopoli, N.
10.1101/2020.10.30.362590 — bioinformatics — Posted on 2020-11-02
4013 Single-dimensional human brain signals for two-dimensional economic choice options
Chi U Seak, L.; Volkmann, K.; Pastor-Bernier, A.; Grabenhorst, F.; Schultz, W.
10.1101/2020.04.06.028001 — neuroscience — Posted on 2020-11-02
4017 Induced pulmonary comorbidities render CD-1 mice sensitive to SARS-CoV-2
Falach, R.; Bar-On, L.; Lazar, S.; Kadar, T.; Mazor, O.; Aftalion, M.; Gur, D.; Shifman, O.; Israeli, O.; Cohen-Gihon, I.; Zaide, G.; Gutman, H.; Evgy, Y.; Vagima, Y.; Makdasi, E.; Stein, D.; Rosenfeld, R.; Alcalay, R.; Zahavy, E.; Levy, H.; Glinert, I.; Ben-Shmuel, A.; Israely, T.; Melamed, S.; Politi, B.; Achdout, H.; Yitzhaky, S.; Kronman, C.; Sabo, T.
10.1101/2020.10.28.358614 — pathology — Posted on 2020-11-02
4018 Priority effects alter interaction outcomes in a legume-rhizobium mutualism
Boyle, J. A.; Simonsen, A. K.; Frederickson, M. E.; Stinchcombe, J. R.
10.1101/2020.10.31.363267 — ecology — Posted on 2020-11-02
4019 A sparse observation model to quantify species interactions in time and space
Ait Kaci Azzou, S.; Singer, L.; Aebischer, T.; Caduff, M.; Wolf, B.; Wegmann, D.
10.1101/815027 — ecology — Posted on 2020-11-02
4020 Tracking H3K27me3 and H4K20me1 during XCI reveals similarities in enrichment dynamics
Tjalsma, S. J. D.; Hori, M.; Sato, Y.; Bousard, A.; Ohi, A.; Raposo, A. C.; Roensch, J.; Le Saux, A.; Nogami, J.; Maehara, K.; Kujirai, T.; Handa, T.; Bages-Arnal, S.; Ohkawa, Y.; Kurumizaka, H.; da Rocha, S. T.; Zylicz, J. J.; Kimura, H.; Heard, E.
10.1101/2020.08.06.228346 — developmental biology — Posted on 2020-11-02
4021 Transfer of Antibiotic Resistance Genes from Gram-positive Bacterium to Gram-negative Bacterium
Manohar, P.; Shanthini, T.; Bozdogan, B.; Lundborg, C. S.; Tamhankar, A. J.; Palaniyar, N.; Ramesh, N.
10.1101/2020.11.01.364331 — microbiology — Posted on 2020-11-02
4025 Orai1- and Orai2-, but not Orai3-mediated ICRAC is regulated by intracellular pH
Rychkov, G.; Zhou, F. H.; Adams, M. K.; Brierley, S. M.; Ma, L.; Barritt, G. J.
10.1101/2020.11.01.364299 — physiology — Posted on 2020-11-02
4027 Development of a Novel Index to Characterise Arterial Dynamics Using Ultrasound Imaging
Ward, J.; Cheng, X.; Xiao, Y.; Lapolla, P.; Chandrashekar, A.; Handa, A.; Cleveland, R.; Lee, R.
10.1101/2020.10.31.363291 — bioengineering — Posted on 2020-11-02
4028 TAD cliques predict key features of chromatin organization
Liyakat Ali, T. M.; Brunet, A.; Collas, P.; Paulsen, J.
10.1101/2020.11.01.363903 — genomics — Posted on 2020-11-02
4031 Microvilli-derived Extracellular Vesicles Govern Morphogenesis in Drosophila wing epithelium
Hurbain, I.; Mace, A.-S.; Romao, M.; Sengmanivong, L.; Ruel, L.; Basto, R.; Therond, P. P.; Raposo, G.; D'Angelo, G.
10.1101/2020.11.01.363697 — cell biology — Posted on 2020-11-02
4032 Sclerostin depletion induces inflammation in the bone marrow of mice
Donham, C.; Chicana, B.; Robling, A. G.; Mohamed, A.; Elizaldi, S.; Chi, M.; Freeman, B.; Millan, A.; Murguesh, D.; Loots, G. G.; Manilay, J. O.
10.1101/2020.11.01.364158 — immunology — Posted on 2020-11-02
4035 Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
Hamza, B.; Miller, A. B.; Meier, L.; Stockslager, M.; King, E. M.; Ng, S. R.; DeGouveia, K. L.; Mulugeta, N.; Calistri, N. L.; Strouf, H.; Lin, L.; Chin, C. R.; Weinberg, R.; Shalek, A. K.; Jacks, T.; Manalis, S.
10.1101/2020.11.01.350918 — cancer biology — Posted on 2020-11-01
4036 Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight
Moen, G.-H.; Beaumont, R. N.; Sommer, C.; Shields, B. M.; Lawlor, D. A.; Freathy, R. M.; Evans, D. M.; Warrington, N. M.
10.1101/2020.01.21.914655 — genetics — Posted on 2020-11-01
4037 Remote control of neural function by X-ray-induced scintillation
Matsubara, T.; Yanagida, T.; Kawaguchi, N.; Nakano, T.; Yoshimoto, J.; Sezaki, M.; Takizawa, H.; Tsunoda, S. P.; Horigane, S.-i.; Ueda, S.; Takemoto-Kimura, S.; Kandori, H.; Yamanaka, A.; Yamashita, T.
10.1101/798702 — neuroscience — Posted on 2020-11-01
4039 Uncovering the mesendoderm gene regulatory network through multi-omic data integration
Jansen, C.; Paraiso, K.; Zhou, J.; Blitz, I. L.; Fish, M.; Charney, R.; Cho, J. S.; Yasuoka, Y.; Sudou, N.; Bright, A. R.; Wlizla, M.; Veenstra, G. J. C.; Taira, M.; Zorn, A.; Mortazavi, A.; Cho, K. W. Y.
10.1101/2020.11.01.362053 — genomics — Posted on 2020-11-01
4042 An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients
The NeuroLINCS Consortium, ; Ornelas, L.; Gomez, E.; Panther, L.; Frank, A.; Lei, S.; Mandefro, B.; Banuelos, M. G.; Shelley, B.; Kaye, J. A.; Lima, L.; Wyman, S.; Lim, R. G.; Wu, J.; Stocksdale, J.; Casale, M.; Dardov, V.; Matlock, A.; Venkatraman, V.; Holewenski, R.; Milani, P.; Adam, M.; Wassie, B. T.; Cheng, A.; Coyne, A. N.; Daigle, J. G.; Li, J.; Yang, S.; Cox, V.; Wilhelm, M.; Lloyd, T. E.; Hayes, L.; Pham, J.; Escalante-Chong, R.; Lenail, A.; Sachs, K.; Patel-Murray, N. L.; Ramamoorthy, D.; Thompson, T. G.; NYGC ALS Consortium, ; Finkbeiner, S.; Fraenkel, E.; Rothstein, J. D.; Sareen
10.1101/2020.11.01.362269 — neuroscience — Posted on 2020-11-01
4043 Intestinal ferritinophagy is regulated by HIF-2 and is essential for systemic iron homeostasis
Das, N. K.; Sankar, A.; Schwartz, A. J.; Solanki, S.; Ma, X.; Parimi, S.; Santana-Codina, N.; Mancias, J. D.; Shah, Y. M.
10.1101/2020.11.01.364059 — physiology — Posted on 2020-11-01
4050 MondoA Drives Malignancy in cALL through Enhanced Adaptation to Metabolic Stress
Sipol, A.; Hameister, E.; Xue, B.; Petry, A.; Prexler, C.; Barenboim, M.; Rubio, R. A.; Baldauf, M. C.; Franchina, D. G.; Schmaeh, J.; Richter, G.; Cario, G.; Gruenewald, T. G. P.; Goerlach, A.; Brenner, D.; Ruland, J.; Sorensen, P. H.; Burdach, S. E. G.
10.1101/2020.11.01.363986 — cancer biology — Posted on 2020-11-01
4051 Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway
Cason, S. E.; Carman, P. J.; Van Duyne, C.; Goldsmith, J.; Dominguez, R.; Holzbaur, E. L. F.
10.1101/2020.11.01.363333 — cell biology — Posted on 2020-11-01
4052 CRISPR-Cas13 mediated Knock Down in Drosophila cultured cells.
Viswanatha, R.; Zaffagni, M.; Zirin, J.; Perrimon, N.; Kadener, S.
10.1101/2020.11.01.364166 — molecular biology — Posted on 2020-11-01
4055 Differential response of macrophages and neutrophils to trypanosome infections in zebrafish: occurrence of foamy macrophages
Jacobs, S. H.; Doro, E.; Hammond, F. R.; Nguyen-Chi, M. E.; Lutfalla, G.; Wiegertjes, G. F.; Forlenza, M.
10.1101/2020.11.01.363721 — microbiology — Posted on 2020-11-01
4056 Genetic diversity of blaKPC-gene-containing IncF plasmids from epidemiologically related and unrelated Enterobacteriaceae
Stohr, J. J. J. M.; Kluytmans-van den Bergh, M. F. Q.; Weterings, V. A. T. C.; Rossen, J. W. A.; Kluytmans, J. A. J. W.
10.1101/2020.11.01.362400 — microbiology — Posted on 2020-11-01
4063 The mammalian CLU homolog FMT controls development and behavior in Arabidopsis
Horvath, T.; Ralevski, A.; Apelt, F.; Olas, J.; Mueller-Roeber, B.; Rugarli, E.; Kragler, F.
10.1101/2020.08.01.231183 — plant biology — Posted on 2020-11-01
4065 A biophysical and structural analysis of DNA binding by oligomeric hSSB1 (NABP2/OBFC2B)
El-Kamand, S.; Jergic, S.; Lawson, T.; Kariawasam, R.; Richard, D. J.; Cubeddu, L.; Gamsjaeger, R.
10.1101/2020.08.26.269084 — biochemistry — Posted on 2020-11-01
4066 Evaluation of the antiviral effect of chlorine dioxide (ClO2) using a vertebrate model inoculated with avian coronavirus
Zambrano-Estrada, X.; Dominguez-Sanchez, C. A.; Banuet-Martinez, M.; Guerrero-de la Rosa, F.; Garcia-Gasca, T.; Prieto-Valiente, L.; Acevedo-Whitehouse, K.
10.1101/2020.10.13.336768 — microbiology — Posted on 2020-11-01
4070 Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations
Miersch, S.; Li, Z.; Saberianfar, R.; Ustav, M.; Blazer, L.; Chen, C.; Ye, W.; Pavlenco, A.; Subramnia, S.; Singh, S.; Ploder, L.; Ganaie, S.; Leung, D.; Case, J. B.; Novelli, G.; Matusali, G.; Chen, R.; Colavita, F.; Copabianchi, M. R.; Jain, S.; Gupta, J. B.; Amarasinghe, G.; Diamond, M. S.; Rini, J.; Sidhu, S.
10.1101/2020.10.31.362848 — synthetic biology — Posted on 2020-11-01
4075 A Connectome-Based Approach to Assess Motor Outcome after Neonatal Arterial Ischemic Stroke
Al Harrach, M.; Pretzel, P.; Groeschel, S.; Dhollander, T.; Hertz-Pannier, L.; Lefevre, J.; Chabrier, S.; Dinomais, M.
10.1101/2020.08.24.265173 — bioengineering — Posted on 2020-11-01
4080 Highly-parallel microfluidics-based force spectroscopy on single cytoskeletal motors
Urbanska, M.; Lüdecke, A.; Walter, W. J.; van Oijen, A. M.; Duderstadt, K. E.; Diez, S.
10.1101/2020.08.11.245910 — biophysics — Posted on 2020-11-01
4081 Advanced Whole Genome Sequencing Using an Entirely PCR-free Massively Parallel Sequencing Workflow
Xia, Z.; Jiang, Y.; Drmanac, R.; Shen, H.; Liu, P.; Li, Z.; Chen, F.; Jiang, H.; Shi, S.; Xi, Y.; Li, Q.; Wang, X.; Zhao, J.; Liang, X.; Xie, Y.; Wang, L.; Tian, W.; Berntsen, T.; Luo, Y.; Gong, M.; Li, J.; Xu, C.; Dai, S.; Mi, Z.; Ren, H.; Lin, Z.; Chen, A.; Zhang, W.; Mu, F.; Xu, X.
10.1101/2019.12.20.885517 — genomics — Posted on 2020-11-01
4084 Comparative transcriptomic analysis reveals conserved transcriptional programs underpinning organogenesis and reproduction in land plants
Julca, I.; Flores, M.; Proost, S.; Lindner, A.-C.; Hackenberg, D.; Steinbachova, L.; Michaelidis, C.; Gomes Pereira, S.; Misra, C. S.; Kawashima, T.; Borg, M.; Berger, F.; Goldberg, J.; Johnson, M.; Honys, D.; Twell, D.; Sprunck, S.; Dresselhaus, T.; Becker, J.; Mutwil, M.
10.1101/2020.10.29.361501 — evolutionary biology — Posted on 2020-11-01
4087 Beauty and the brain: Investigating the neural and musical attributes of beauty during a naturalistic music listening experience
Brattico, E.; Brusa, A.; Dietz, M. J.; Jacobsen, T.; Fernandes, H.; Gaggero, G.; Toiviainen, P.; Vuust, P.; Proverbio, A. M.
10.1101/2020.10.31.363283 — neuroscience — Posted on 2020-11-01
4089 Genome ARTIST_v2 software - a support for annotation of class II natural transposons in new sequenced genomes
Ecovoiu, A. A.; Ghita, I. C.; Chifiriuc, D. I. M.; Ghionoiu, I. C.; Ciuca, A. M.; Bologa, A. M.; Ratiu, A. C.
10.1101/2020.10.30.360610 — bioinformatics — Posted on 2020-11-01
4091 An efficient and accurate frailty model approach for genome-wide survival association analysis controlling for population structure and relatedness in large-scale biobanks
Dey, R.; Zhou, W.; Kiiskinen, T.; Havulinna, A.; Elliott, A.; Karjalainen, J.; Kurki, M.; Qin, A.; FinnGen, ; Lee, S.; Palotie, A.; Neale, B. M.; Daly, M. J.; Lin, X.
10.1101/2020.10.31.358234 — genomics — Posted on 2020-11-01
4092 Infant Inhibited Temperament in Primates Predicts Adult Behavior, is Heritable, and is Associated with Anxiety Relevant Genetic Variation
Fox, A. S.; Harris, R. A.; Del Rosso, L.; Raveendran, M.; Kamboj, S.; Kinnally, E. L.; Capitanio, J. P.; Rogers, J.
10.1101/2020.10.30.361477 — genetics — Posted on 2020-11-01
4093 MINSTED fluorescence localization and nanoscopy
Weber, M.; Leutenegger, M.; Stoldt, S.; Jakobs, S.; Mihaila, T. S.; Butkevich, A. N.; Hell, S. W.
10.1101/2020.10.31.363424 — biophysics — Posted on 2020-11-01
4095 Climate influences the response of community functional traits to local conditions
Guzman, L. M.; Trzcinski, M. K.; Barberis, I. M.; Cereghino, R.; Srivastava, D. S.; Gilbert, B.; Pillar, V.; De Omena, P.; MacDonald, A. A. M.; Corbara, B.; Leroy, C.; Ospina Bautista, F.; Romero, G. Q.; Katrina, P.; Debastiani, V. J.; Goncalves, A. Z.; Marino, N. A. C.; Farjalla, V.; Richardson, B.; Richardson, M. J.; Dezerald, O.; Piccoli, G. C. O.; Jocque, M.; Montero, G.
10.1101/2020.10.30.362525 — ecology — Posted on 2020-11-01
4100 Photosynthetic activity triggers pH and NAD redox signatures across different plant cell compartments
Elsässer, M.; Feitosa-Araujo, E.; Lichtenauer, S.; Wagner, S.; Fuchs, P.; Giese, J.; Kotnik, F.; Hippler, M.; Meyer, A.; Maurino, V. G.; Finkemeier, I.; Schallenberg-Rüdinger, M.; Schwarzländer, M.
10.1101/2020.10.31.363051 — plant biology — Posted on 2020-11-01
4107 Paper-based Sensing of Fucosylated Biological Compounds
Enam, F.; Mansell, T. J.; Kramer, E.; Robinson, F.; Alvarez-Acosta, A.; Cademartiri, R.
10.1101/2020.10.30.362889 — biochemistry — Posted on 2020-11-01
4112 Occurrence but not intensity of mortality rises towards the climatic trailing edge of tree species ranges in European forests.
Changenet, A.; Ruiz-Benito, P.; Ratcliffe, S.; Frejaville, T.; Archambeau, J.; Porte, A. J.; Zavala, M. A.; Dahlgren, J.; Lehtonen, A.; Benito Garzon, M.
10.1101/2020.10.30.362087 — ecology — Posted on 2020-11-01
4114 Hippocampus shape across the healthy lifespan and its relationship with cognition
Bussy, A.; Patel, R.; Plitman, E.; Tullo, S.; Salaciak, A.; Bedford, S.; Farzin, S.; Beland, M.-L.; Valiquette, V.; Kazazian, C.; Tardif, C.; Devenyi, G.; Chakravarty, M.
10.1101/2020.10.30.362921 — neuroscience — Posted on 2020-11-01
4118 Evaluation of azithromycin or hydroxychloroquine plus azithromycin combination therapy on cardiac conduction and function in guinea pigs
Li, X.; Tan, W.; Zheng, S.; Sun, H.; Zhang, X.; Li, X.; Chen, H.; Ren, X.; He, T.; Zhu, C.; Zhang, Y.; Yang, F. H.
10.1101/2020.10.31.362566 — physiology — Posted on 2020-11-01
4120 Ethnicity-specific transcriptomic variation in immune cells and correlation with disease activity in systemic lupus erythematosus
Andreoletti, G.; Lanata, C. M.; Paranjpe, I.; Jain, T. S.; Nititham, J.; Taylor, K. E.; Combes, A. J.; Maliskova, L.; Jimmie Ye, C.; Katz, P.; Dall Era, M.; Yazdany, J.; Criswell, L. A.; Sirota, M.
10.1101/2020.10.30.362715 — bioinformatics — Posted on 2020-11-01
4122 Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins
Singh, N.; Reyes-Ordonez, A.; Compagnone, M. A.; Moreno Castillo, J. F.; Leslie, B. J.; Ha, T.; Chen, J.
10.1101/2020.06.20.163253 — biochemistry — Posted on 2020-11-01
4123 Structural Basis of Stu2 Recruitment to Yeast Kinetochores
Zahm, J. A.; Stewart, M. G.; Carrier, J. S.; Harrison, S. C.; Miller, M. P.
10.1101/2020.10.31.362574 — biochemistry — Posted on 2020-11-01
4127 CryoET structures of immature HIV Gag reveal a complete six-helix bundle and stabilizing small molecules distinct from IP6
Mendonca, L.; Sun, D.; Ning, J.; Liu, J.; Kotecha, A.; Olek, M.; Frosio, T.; Fu, X.; Himes, B. A.; Kleinpeter, A. B.; Freed, E. O.; Zhou, J.; Aiken, C.; Zhang, P.
10.1101/2020.10.31.363382 — microbiology — Posted on 2020-11-01