bioRxiv directory

Irigoyen, N.; Franaszek, K.; Dinan, A. M.; Moore, N. A.; Siddell, S. G.; Brierley, I.; Firth, A. E.

10.1101/292979 — microbiology — Posted on 2018-03-31

3 Antibody-based vaccine for TB: pre-clinical validation in horse foals challenged with the TB-related pathogen Rhodococcus equi

Cywes-Bentley, C.; Rocha, J. N.; Bordin, A. I.; Vinacur, M.; Rehman, S.; Zaidi, T. S.; Meyer, M.; Anthony, S.; Lambert, M.; Vlock, D. R.; Giguere, S.; Cohen, N. D.; Pier, G. B.

10.1101/292946 — immunology — Posted on 2018-03-31

4 Natural selection on gene-specific codon usage bias is common across eukaryotes

Peng, Z.; Zaher, H.; Ben-Shahar, Y.

10.1101/292938 — evolutionary biology — Posted on 2018-03-31

5 Chorioamnionitis as a risk factor for retinopathy of prematurity: an updated systematic review and meta-analysis

Villamor-Martinez, E.; Cavallaro, G.; Raffaeli, G.; Mohammed Rahim, O. M. M.; Gulden, S.; Ghazi, A. M. T.; Mosca, F.; Degraeuwe, P.; Villamor, E.

10.1101/291476 — epidemiology — Posted on 2018-03-31

6 A systematic review of social contact surveys to inform transmission models of close contact infections

Hoang, T. V.; Coletti, P.; Melegaro, A.; Wallinga, J.; Grijalva, C.; Edmunds, J.; Beutels, P.; Hens, N.

10.1101/292235 — epidemiology — Posted on 2018-03-31

7 Surveillance of CKD epidemiology in the US -- a joint analysis of NHANES and KEEP

Myers, O. B.; Pankratz, V. S.; Norris, K. C.; Vassalotti, J. A.; Unruh, M. L.; Argyropoulos, C.

10.1101/292698 — epidemiology — Posted on 2018-03-31

8 Ebola outbreak brings to light an unforeseen impact of tsetse control on sleeping sickness transmission in Guinea.

Kagbadouno, M. S.; Camara, O.; Camara, M.; Ilboudo, H.; Camara, M. L.; Rayaisse, J.-B.; Diaby, A.; Taore, B.; Leno, M.; Courtin, F.; Jamonneau, V.; Solano, P.; Bucheton, B.

10.1101/202762 — epidemiology — Posted on 2018-03-31

9 Differential human mobility and local variation in human infection attack rate

Haw, D. J.; Cummings, D. A. T.; Lessler, J.; Salje, H.; Read, J. M.; Riley, S.

10.1101/291674 — epidemiology — Posted on 2018-03-31

10 Trends in outpatient antibiotic prescribing practice among US older adults, 2011-2015: an observational study

Olesen, S. W.; Barnett, M. L.; MacFadden, D. R.; Lipsitch, M.; Grad, Y. H.

10.1101/292243 — epidemiology — Posted on 2018-03-31

11 Locomotor response to acute stressors requires hypothalamic-pituitary-interrenal axis activation and glucocorticoid receptors in zebrafish

Lee, H. B.; Schwab, T. L.; Sigafoos, A. N.; Gauerke, J. L.; Krug, R. G.; Serres, M. R.; Jacobs, D. C.; Cotter, R. P.; Das, B.; Petersen, M. O.; Daby, C. L.; Urban, R. M.; Berry, B. C.; Clark, K. J.

10.1101/291914 — neuroscience — Posted on 2018-03-31

12 Widespread noncoded amino acids in human proteome

Yang, J.-H.; Chen, X.; Gong, J.; Zhao, H.; Li, C.; Bi, B.; Wang, F.; Sun, S.; Wang, X.; Lv, X.; Zhang, B.; Huang, T.; Azadzoi, K.; Shi, F.; Kong, X.; Shu, M.; Wang, Y.; Chin, Y. E.; Huang, W.; Chen, Z.; Chen, Z.-J.

10.1101/292474 — molecular biology — Posted on 2018-03-31

13 Lag Penalized Weighted Correlation for Time Series Clustering

Chandereng, T.; Gitter, A.

10.1101/292615 — bioinformatics — Posted on 2018-03-31

14 Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma

Orth, M. F.; Gerke, J. S.; Knosel, T.; Altendorf-Hofmann, A.; Musa, J.; Alba Rubio, R.; Stein, S.; Dallmayer, M.; Baldauf, M. C.; Marchetto, A.; Sannino, G.; Ohmura, S.; Li, J.; Hakozaki, M.; Kirchner, T.; Dandekar, T.; Butt, E.; Grunewald, T. G. P.

10.1101/292805 — pathology — Posted on 2018-03-31

15 Sidewall cell envelope synthesis and remodeling in pole-growing mycobacteria

Garcia-Heredia, A.; Pohane, A. A.; Melzer, E. S.; Fiolek, T. J.; Rundell, S. R.; Lim, H. C.; Wagner, J.; Morita, Y. S.; Swarts, B. M.; Siegrist, M. S.

10.1101/292607 — microbiology — Posted on 2018-03-31

16 Sex differences in gene expression in response to ischemia in the human myocardium

Stone, G.; Choi, A.; Oliva, M.; Gorham, J.; Heydarpour, M.; Seidman, C. E.; Seidman, J. G.; Aranki, S. F.; Body, S. C.; Carey, V. J.; Raby, B. A.; Stranger, B. E.; Muehlschlegel, J. D.

10.1101/282350 — genomics — Posted on 2018-03-31

17 Influence of elevated CO2 on development and food utilization of target armyworm Mythimna separata fed on transgenic Bt maize infected by nitrogen-fixing bacteria

Li, Z.; Song, Y.; Li, L.; Wang, L.; Liu, B.; Parajulee, M. N.; Chen, F.

10.1101/292565 — ecology — Posted on 2018-03-31

18 A unifying framework for summary statistic imputation

Wu, Y.; Eskin, E.; Sankararaman, S.

10.1101/292664 — bioinformatics — Posted on 2018-03-31

19 Mapping the Dark Side: Visual Selectivity of Default Network Deactivations

Knapen, T.; van Es, D.; Barendregt, M.

10.1101/292524 — neuroscience — Posted on 2018-03-31

20 Predictive control of electrophysiological network architecture using direct, single-node neurostimulation in humans

Khambhati, A. N.; Kahn, A. E.; Costantini, J.; Ezzyat, Y.; Solomon, E. A.; Gross, R. E.; Jobst, B. C.; Sheth, S. A.; Zaghloul, K. A.; Worrell, G.; Seger, S.; Lega, B. C.; Weiss, S.; Sperling, M. R.; Gorniak, R.; Das, S. R.; Stein, J. M.; Rizzuto, D. S.; Kahana, M. J.; Lucas, T. H.; Davis, K. A.; Tracy, J. I.; Bassett, D. S.

10.1101/292748 — neuroscience — Posted on 2018-03-31

21 Effects of exclusive breastfeeding on infant gut microbiota: a meta-analysis across studies and populations

Ho, N. T.; Li, F.; Lee-Sarwar, K. A.; Tun, H. M.; Brown, B.; Pannaraj, P. S.; Wood, L. F.; Bender, J. M.; Sordillo, J. E.; Azad, M. B.; Thompson, A. L.; Weiss, S. T.; Azcarate-Peril, M. A.; Litonjua, A. A.; Kozyrskyj, A. L.; Jaspan, H. B.; Aldrovandi, G. M.; Kuhn, L.

10.1101/292755 — microbiology — Posted on 2018-03-31

22 Directional selection limits ecological diversification and promotes ecological tinkering during the competition for substitutable resources

Good, B. H.; Martis, S.; Hallatschek, O.

10.1101/292821 — evolutionary biology — Posted on 2018-03-31

23 Adaptation to local climate in size, growth and phenology across 19 silver fir (Abies alba Mill.) populations from Switzerland

Csillery, K.; Sperisen, C.; Ovaskainen, O.; Widmer, A.; Gugerli, F.

10.1101/292540 — evolutionary biology — Posted on 2018-03-31

24 Classification of early and late stage Liver Hepatocellular Carcinoma patients from their genomics and epigenomics profiles.

Kaur, H.; Bhalla, S.; Raghava, G. P. S.

10.1101/292854 — bioinformatics — Posted on 2018-03-31

25 Short cracks in knee meniscus tissue cause strain concentrations, but not weakness, in single-cycle uniaxial tension

Peloquin, J. M.; Santare, M. H.; Elliott, D. M.

10.1101/292623 — bioengineering — Posted on 2018-03-31

26 CliqueSNV: Scalable Reconstruction of Intra-Host Viral Populations from NGS Reads

Knyazev, S.; Tsyvina, V.; Melnyk, A.; Artyomenko, A.; Malygina, T.; Porozov, Y. B.; Campbell, E.; Switzer, W. M.; Skums, P.; Zelikovsky, A.

10.1101/264242 — bioinformatics — Posted on 2018-03-31

27 Polygonal motion and adaptable phototaxis via flagellar beat switching in Euglena gracilis

Tsang, A. C. H.; Lam, A. T.; Riedel-Kruse, I. H.

10.1101/292896 — biophysics — Posted on 2018-03-31

28 Integrating Predicted Transcriptome From Multiple Tissues Improves Association Detection

Barbeira, A. N.; Pividori, M. D.; Zheng, J.; Wheeler, H. E.; Nicolae, D. L.; Im, H. K.

10.1101/292649 — genomics — Posted on 2018-03-31

29 The Genomic Formation of South and Central Asia

Narasimhan, V. M.; Patterson, N. J.; Moorjani, P.; Lazaridis, I.; Mark, L.; Mallick, S.; Rohland, N.; Bernardos, R.; Kim, A. M.; Nakatsuka, N.; Olalde, I.; Coppa, A.; Mallory, J.; Moiseyev, V.; Monge, J.; Olivieri, L. M.; Adamski, N.; Broomandkhoshbacht, N.; Candilio, F.; Cheronet, O.; Culleton, B. J.; Ferry, M.; Fernandes, D.; Gamarra, B.; Gaudio, D.; Hajdinjak, M.; Harney, E.; Harper, T. K.; Keating, D.; Lawson, A.-M.; Michel, M.; Novak, M.; Oppenheimer, J.; Rai, N.; Sirak, K.; Slon, V.; Stewardson, K.; Zhang, Z.; Akhatov, G.; Bagashev, A. N.; Baitanayev, B.; Bonora, G. L.; Chikisheva, T.; D

10.1101/292581 — genomics — Posted on 2018-03-31

30 Glucocorticoid receptor gene polymorhisms and breast cancer: significant association in cancerous tissue samples from Turkish patients

Akyildiz, G.; Akkiprik, M.; Ozer, A.; Kaya, H.; Gulluoglu, B. M.; Aral, C.

10.1101/292631 — cancer biology — Posted on 2018-03-31

31 Small RNA-mediated genomic silencing promotes telomere stability in the absence of telomerase

Longtine, C.; Frenk, S.; ahmed, s.

10.1101/292722 — genetics — Posted on 2018-03-31

32 Protein structure and function analyses to understand the implication of mutually exclusive splicing

Lam, S. D.; Orengo, C.; Lees, J.

10.1101/292813 — bioinformatics — Posted on 2018-03-31

33 Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors

Santiago, A. d. S.; Counago, R. M.; Zonzini Ramos, P.; Godoi, P. H. C.; Massirer, K. B. B.; Gileadi, O.; Elkins, J.

10.1101/292797 — biochemistry — Posted on 2018-03-31

34 A phylogenomic framework and timescale for comparative studies of tunicates

Delsuc, F.; Philippe, H.; Tsagkogeorga, G.; Simion, P.; Tilak, M.-K.; Turon, X.; Lopez-Legentil, S.; Piette, J.; Lemaire, P.; Douzery, E. J. P.

10.1101/236448 — evolutionary biology — Posted on 2018-03-31

35 Seeing spots: Measuring, quantifying heritability, and assessing fitness consequences of coat pattern traits in a wild population of giraffes (Giraffa camelopardalis)

Lee, D. E.; Cavener, D. R.; Bond, M. L.

10.1101/161281 — evolutionary biology — Posted on 2018-03-31

36 A specific, glycomimetic Langerin ligand for human Langerhans cell targeting

Wamhoff, E.-C.; Schulze, J.; Bellmann, L.; Bachem, G.; Fuchsberger, F. F.; Rademacher, J.; Hermann, M.; Del Frari, B.; van Dalen, R.; Hartmann, D.; van Sorge, N.; Seitz, O.; Stoitzner, P.; Rademacher, C.

10.1101/286021 — immunology — Posted on 2018-03-31

37 Integrative analysis of transcription factor occupancy at enhancers and disease risk loci in noncoding genomic regions

Oki, S.; Ohta, T.; Shioi, G.; Hatanaka, H.; Ogasawara, O.; Okuda, Y.; Kawaji, H.; Nakaki, R.; Sese, J.; Meno, C.

10.1101/262899 — genomics — Posted on 2018-03-31

38 Quantifying configuration-sampling error in Langevin simulations of complex molecular systems

Fass, J.; Sivak, D.; Crooks, G. E.; Beauchamp, K. A.; Leimkuhler, B.; Chodera, J.

10.1101/266619 — biophysics — Posted on 2018-03-31

39 The accuracy of LD Score regression as an estimator of confounding and genetic correlations in genome-wide association studies

Lee, J. J.; McGue, M.; Iacono, W. G.; Chow, C. C.

10.1101/234815 — genetics — Posted on 2018-03-31

40 Insect wings and body wall evolved from ancient leg segments

Bruce, H. S.; Patel, N. H.

10.1101/244541 — developmental biology — Posted on 2018-03-31

41 Experimental signal dissection and method sensitivity analyses reaffirm the potential of fossils and morphology in the resolution of the relationship of angiosperms and Gnetales

Coiro, M.; Chomicki, G.; Doyle, J. A.

10.1101/134262 — evolutionary biology — Posted on 2018-03-31

42 Optical recording of action potential initiation and propagation in mouse skeletal muscle fibers

Banks, Q.; Pratt, S. J. P.; Iyer, S. R.; Lovering, R. M.; Hernandez-Ochoa, E.; Schneider, M. F.

10.1101/292391 — biophysics — Posted on 2018-03-31

43 Monitoring Unfolding of Titin I27 single- and bi-Domain with High-Pressure NMR Spectroscopy.

ROUMESTAND, C.; HERRADA, I.; VAN HEUSDEN, M.; BARTHE, P.; DEGUILLEN, K.; MAMMRI, L.; DELBECQ, S.; Rico, F.

10.1101/292359 — biophysics — Posted on 2018-03-31

44 Dimerization of rhomboid protease RHBDL2 in lipid membranes addressed by FRET with MC simulations

Skerle, J.; Humpolickova, J.; Rampirova, P.; Polachova, E.; Adamkova, L.; Suchankova, A.; Jakubec, D.; Strisovsky, K.

10.1101/292318 — biophysics — Posted on 2018-03-31

45 Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

Kirchdoerfer, R. N.; Wang, N.; Pallesen, J.; Wrapp, D.; Turner, H. L.; Cotrell, C. A.; Corbett, K. S.; Graham, B. S.; McLellan, J. S.; Ward, A. B.

10.1101/292672 — biochemistry — Posted on 2018-03-31

46 Visual physiology of the Layer 4 cortical circuit in silico

Arkhipov, A.; Gouwens, N. W.; Billeh, Y. N.; Gratiy, S.; Iyer, R.; Wei, Z.; Xu, Z.; Berg, J.; Buice, M.; Cain, N.; da Costa, N.; de Vries, S.; Denman, D.; Durand, S.; Feng, D.; Jarsky, T.; Lecoq, J.; Lee, B.; Li, L.; Mihalas, S.; Ocker, G. K.; Olsen, S. R.; Reid, R. C.; Soler-Llavina, G.; Sorensen, S. A.; Wang, Q.; Waters, J.; Scanziani, M.; Koch, C.

10.1101/292839 — neuroscience — Posted on 2018-03-31

47 Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

Olova, N.; Simpson, D. J.; Marioni, R.; Chandra, T.

10.1101/292680 — developmental biology — Posted on 2018-03-31

48 The Organization of Membranes Below 100 nm: Experimental Breakthroughs Occasion a Modeling Manifesto

Lyman, E.; Eggeling, C.; Hsieh, C.-L.

10.1101/292383 — biophysics — Posted on 2018-03-31

49 Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network

Dhawan, A.; Harris, A. L.; Buffa, F. M.; Scott, J. G.

10.1101/292029 — systems biology — Posted on 2018-03-31

50 Reductions in Retrieval Competition Predict the Benefit of Repeated Testing

Rafidi, N. S.; Hulbert, J. C.; Pacheco, P.; Norman, K. A.

10.1101/292557 — neuroscience — Posted on 2018-03-30

51 Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots

Dashti, A.; Ben Hail, D.; Mashayekhi, G.; Schwander, P.; des Georges, A.; Frank, J.; Ourmazd, A.

10.1101/291922 — biophysics — Posted on 2018-03-30

52 Mass Spectra alignment using virtual lock-masses

Brochu, F.; Plante, P.-L.; Drouin, A.; Laviolette, F.; Marchand, M.; Corbeil, J.

10.1101/292425 — bioinformatics — Posted on 2018-03-30

53 Stimulus predictability does not modulate bottom-up attentional capture

Meijs, E.; Klaassen, F. H.; Bokeria, L.; van Gaal, S.; de Lange, F.

10.1101/292508 — neuroscience — Posted on 2018-03-30

54 Beta diversity patterns derived from island biogeography theory

Lu, M.; Vasseur, D.; Jetz, W.

10.1101/292490 — ecology — Posted on 2018-03-30

55 ImageJ Macro for Counting Stationary vs. Moving Items in Videos

Douglas, T. A.; Davalos, R. V.

10.1101/292417 — cell biology — Posted on 2018-03-30

56 The Structural Basis of IKs Ion-Channel Activation: Mechanistic Insights from Molecular Simulations

Ramasubramanian, S.; Rudy, Y.

10.1101/275180 — biophysics — Posted on 2018-03-30

57 Mechanical Properties of a Primary Cilium from the Stochastic Motions of the Cilium Tip

Resnick, A.; Feng, Z.; Peng, Z.; Young, Y.-N.; Flaherty, J.

10.1101/292409 — biophysics — Posted on 2018-03-30

58 Plus-end directionality is present in the catalytic core of kinesin-14 minus-end directed motors.

Yajima, J.; Yamagishi, M.

10.1101/292375 — biophysics — Posted on 2018-03-30

59 ADS-J1 Disaggregates Semen-derived Amyloid Fibrils

Li, J.; Yang, Z.; Liu, H.; Lan, Y.; Zhang, T.; Li, W.; Qi, T.; Qiu, Y.; Li, L.; zhou, X.; Liu, S.; Tan, S.

10.1101/292342 — pharmacology and toxicology — Posted on 2018-03-30

60 Hippocampal signature of associative memory measured by chronic ambulatory intracranial EEG

Henin, S.; Shankar, A.; Hasulak, N.; Friedman, D.; Dugan, P.; Melloni, L.; Flinker, A.; Sarac, C.; Fang, M.; Doyle, W.; Tcheng, T.; Devinsky, O.; Davachi, L.; Liu, A.

10.1101/291740 — neuroscience — Posted on 2018-03-30

61 Chemotaxis model for human breast cancer cells based on signal-to-noise ratio

Lim, S.; Nam, H.; Jeon, J. S.

10.1101/292300 — biophysics — Posted on 2018-03-30

62 Holographic optical trapping Raman micro-spectroscopy for interacting live cells

Sinjab, F.; Notingher, I.; Elsheikha, H. M.; Awuah, D.; Gibson, G.; Padgett, M.; Ghaemmaghami, A. M.

10.1101/292334 — biophysics — Posted on 2018-03-30

63 Nonlinear calcium ion waves along actin filaments control active hair-bundle motility

Tuszynski, J. A.; Sataric, B. M.; Sataric, M. V.; Sekulic, D. L.; Zdravkovic, S.

10.1101/292292 — biophysics — Posted on 2018-03-30

64 Using Optimal F-Measure and Random Resampling in Gene Ontology Enrichment Calculations

Ge, W.; Fazal, Z.; Jakobsson, E.

10.1101/218248 — bioinformatics — Posted on 2018-03-30

65 HIV-1 Env gp41 Transmembrane Domain Dynamics are Modulated by Lipid, Water, and Ion Interactions

Hollingsworth, L. R.; Lemkul, J.; Bevan, D. R.; Brown, A. M.

10.1101/292326 — biophysics — Posted on 2018-03-30

66 Estimating RNA structure chemical probing reactivities from reverse transcriptase stops and mutations.

Yu, A. M.; Evans, M. E.; Lucks, J. B.

10.1101/292532 — biochemistry — Posted on 2018-03-30

67 Identifying G protein-coupled receptor dimers from crystal packings

Stenkamp, R. E.

10.1101/282178 — biophysics — Posted on 2018-03-30

68 Precision inhibitory stimulation of individual-specific cortical hubs disrupts information processing in humans

Lynch, C. J.; Breeden, A.; Gordon, E. M.; Cherry, J. B.; Turkeltaub, P. E.; Vaidya, C. J.

10.1101/254417 — neuroscience — Posted on 2018-03-30

69 A post-transcriptional regulatory code for mRNA stability during the zebrafish maternal-to-zygotic transition

Vejnar, C. E.; Abdel Messih, M.; Takacs, C. M.; Yartseva, V.; Oikonomou, P.; Christiano, R.; Stoeckius, M.; Lau, S.; Lee, M. T.; Beaudoin, J.-D.; Darwich-Codore, H.; Walther, T. C.; Tavazoie, S.; Cifuentes, D.; Giraldez, A. J.

10.1101/292441 — genomics — Posted on 2018-03-30

70 Exonic unpaired elements modulate pre-mRNA structure for splice site recognition

Saha, K.; Biswas, T.; Fernandez, M. M.; England, W.; Spitale, R.; Ghosh, G.

10.1101/292003 — biochemistry — Posted on 2018-03-30

71 In vitro assembly of an early spliceosome defining both splice sites

Saha, K.; Fernandez, M. M.; Biswas, T.; Lumba, C. L.; Ghosh, G.

10.1101/292458 — biochemistry — Posted on 2018-03-30

72 A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 nucleases in rice

Tang, X.; Liu, G.; Zhou, J.; Ren, Q.; You, Q.; Tian, L.; Xin, X.; Zhong, Z.; Liu, B.; Zheng, X.; Zhang, D.; Malzahn, A.; Gong, Z.; Qi, Y.; Zhang, T.; Zhang, Y.

10.1101/292086 — molecular biology — Posted on 2018-03-30

73 Widespread and polymorphous noncoding amino acid residues in human sperm proteome

10.1101/292474 — molecular biology — Posted on 2018-03-30

74 Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

Sundaramoorthy, R.; Hughes, A.; El-Mkami, H.; Norman, D.; Owen-Hughes, T.

10.1101/290874 — molecular biology — Posted on 2018-03-30

75 A computational model of shared fine-scale structure in the human connectome

Guntupalli, J. S.; Ma, F.; Haxby, J. V.

10.1101/108738 — neuroscience — Posted on 2018-03-30

76 Reciprocal control of motility and biofilm formation by the PdhS2 two-component sensor kinase of Agrobacterium tumefaciens

Heindl, J. E.; Crosby, D.; Brar, S.; Singletary, T.; Merenich, D.; Eagan, J. L.; Buechlein, A. M.; Bruger, E. L.; Waters, C. M.; Fuqua, C.

10.1101/148429 — microbiology — Posted on 2018-03-30

77 Pisces: An Accurate and Versatile Variant Caller for Somatic and Germline Next-Generation Sequencing Data

Dunn, T.; Berry, G.; Emig-Agius, D.; Jiang, Y.; Lei, S.; Iyer, A.; Udar, N.; Chuang, H.-Y.; Hegarty, J.; Dickover, M.; Klotzle, B.; Robbins, J.; Bibikova, M.; Peeters, M.; Stromberg, M.

10.1101/291641 — bioinformatics — Posted on 2018-03-30

78 BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language

Hoyt, C. T.; Domingo-Fernandez, D.; Hofmann-Apitius, M.

10.1101/288274 — systems biology — Posted on 2018-03-30

79 A Multi-Species Functional Embedding Integrating Sequence and Network Structure

Fan, J.; Cannistra, A.; Fried, I.; Lim, T.; Schaffner, T.; Crovella, M.; Hescott, B.; Leiserson, M. D.

10.1101/229211 — bioinformatics — Posted on 2018-03-30

80 Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Bansal, M.; he, j.; Peyton, M.; Kaustagi, M.; Iyer, A.; Comb, M.; White, M.; Minna, J.; Califano, A.

10.1101/289603 — systems biology — Posted on 2018-03-30

81 Maturing Mycobacterial Peptidoglycan Required Non-canonical Crosslinks to Maintain Shape

Baranowski, C.; Sham, L.-T.; Eskandarian, H. A.; Welsh, M. A.; Lim, H. C.; Kieser, K. J.; Wagner, J. C.; Walker, S.; McKinney, J. D.; Fantner, G. E.; Ioerger, T. R.; Bernhardt, T. G.; Rubin, E. J.; Rego, E. H.

10.1101/291823 — microbiology — Posted on 2018-03-30

82 Porter 5: state-of-the-art ab initio prediction of protein secondary structure in 3 and 8 classes

Torrisi, M.; Kaleel, M.; Pollastri, G.

10.1101/289033 — bioinformatics — Posted on 2018-03-30

83 Data-driven analysis of motor activity implicated 5-HT2A neurons in backward locomotion of larval Drosophila

Park, J.; Kondo, S.; Tanimoto, H.; Kohsaka, H.; Nose, A.

10.1101/257568 — neuroscience — Posted on 2018-03-30

84 DIMEdb: an integrated database and web service for metabolite identification in direct infusion mass spectrometery

O'Shea, K.; Kattupalli, D.; Mur, L. A.; Hardy, N. W.; Misra, B. B.; Lu, C.

10.1101/291799 — bioinformatics — Posted on 2018-03-30

85 The Latent Semantic Space and Corresponding Brain Regions of the Functional Neuroimaging Literature

Alhazmi, F. H.; Beaton, D.; Abdi, H.

10.1101/157826 — neuroscience — Posted on 2018-03-30

86 The ERK MAPK pathway modulates Gq-dependent locomotion in Caenorhabditis elegans

Coleman, B.; Topalidou, I.; Ailion, M.

10.1101/231746 — genetics — Posted on 2018-03-30

87 Label-free prediction of three-dimensional fluorescence images from transmitted light microscopy

Ounkomol, C.; Seshamani, S.; Maleckar, M. M.; Collman, F.; Johnson, G.

10.1101/289504 — cell biology — Posted on 2018-03-30

88 Comparative Annotation Toolkit (CAT) - simultaneous clade and personal genome annotation

Fiddes, I. T.; Armstrong, J.; Diekhans, M.; Nachtweide, S.; Kronenberg, Z. N.; Underwood, J. G.; Gordon, D.; Earl, D.; Keane, T.; Eichler, E. E.; Haussler, D.; Stanke, M.; Paten, B.

10.1101/231118 — bioinformatics — Posted on 2018-03-30

89 BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language

Hoyt, C. T.; Domingo-Fernandez, D.; Hofmann-Apitius, M.

10.1101/288274 — systems biology — Posted on 2018-03-30

90 Analysis of genome-wide differentiation between native and introduced populations of the cupped oysters Crassostrea gigas and Crassostrea angulata

Gagnaire, P.-A.; Lamy, J.-B.; Cornette, F.; Heurtebise, S.; Degremont, L.; Flahauw, E.; Boudry, P.; Bierne, N.; Lapegue, S.

10.1101/292144 — evolutionary biology — Posted on 2018-03-30

91 Systematic analysis of mouse genome reveals distinct evolutionary and functional properties among circadian and ultradian genes

Castellana, S.; Mazza, T.; Capocefalo, D.; Genov, N.; Biagini, T.; Fusilli, C.; Scholkmann, F.; Relogio, A.; Hogenesch, J.; Mazzoccoli, G.

10.1101/197111 — bioinformatics — Posted on 2018-03-30

92 Non-parametric and semi-parametric support estimation using SEquential RESampling random walks on biomolecular sequences

Wang, W.; Smith, J.; Hejase, H.; Liu, K. J.

10.1101/292078 — bioinformatics — Posted on 2018-03-30

93 An easy estimate of the PFDD for a plant illuminated with white LEDs: 1000 lx = 15 μmol/s/m2

Sharakshane, A.

10.1101/289280 — plant biology — Posted on 2018-03-30

94 Motor adaptation but not internal model recalibration declines with aging

Vandevoorde, K.; Orban de Xivry, J.-J.

10.1101/292250 — neuroscience — Posted on 2018-03-30

95 System level analyses of motor-related neural activities in larval Drosophila

Yoon, Y.; Park, J.; Atsushi, T.; Kohsaka, H.; Nakae, K.; Nonaka, S.; Ishii, S.; Nose, A.

10.1101/292136 — neuroscience — Posted on 2018-03-30

96 An ultra-dense haploid genetic map for evaluating the highly fragmented genome assembly of Norway spruce (Picea abies)

Bernhardsson, C.; Vidalis, A.; Wang, X.; Scofield, D. G.; Shiffthaler, B.; Baison, J.; Street, N. R.; Garcia Gil, M. R.; Ingvarsson, P. K.

10.1101/292151 — genetics — Posted on 2018-03-30

97 Cryptic selection forces and dynamic heritability in generalized phenotypic evolution

Gilpin, W.; Feldman, M. W.

10.1101/291963 — evolutionary biology — Posted on 2018-03-30

98 Leaps and bounds: geographical and ecological distance constrained the colonisation of the Afrotemperate by Erica

Pirie, M. D.; Kandziora, M.; Nuerk, N. M.; Le Maitre, N. C.; Mugrabi de Kuppler, A. L.; Gehrke, B.; Oliver, E. G. H.; Bellstedt, D. U.

10.1101/290791 — evolutionary biology — Posted on 2018-03-30

99 Characterisation of palytoxin from an undescribed Palythoa (Anthozoa: Zoantharia: Sphenopidae) with significant in vitro cytotoxic effects on cancer cells at picomolar doses

Sawelew, L.; Gault, F.; Nuccio, C.; Perez, Y.; Lorquin, J.

10.1101/292219 — cancer biology — Posted on 2018-03-30

100 Using a System’s Equilibrium Behavior to Reduce Its Energy Dissipation in Non-Equilibrium Processes

Tafoya, S.; Large, S.; Liu, S.; Bustamante, C.; Sivak, D.

10.1101/291989 — biophysics — Posted on 2018-03-30

101 Can AI reproduce observed chemical diversity?

Benhenda, M.

10.1101/292177 — bioinformatics — Posted on 2018-03-30

102 A deep learning approach for uncovering lung cancer immunome patterns

Hess, M.; Lenz, S.; Binder, H.

10.1101/291047 — bioinformatics — Posted on 2018-03-30

103 Sensitivity Levels: Optimizing the Performance of Privacy Preserving DNA Alignment

Fernandes, M.; Decouchant, J.; Voelp, M.; M Couto, F.; Esteves-Verissimo, P.

10.1101/292227 — bioinformatics — Posted on 2018-03-30

104 Accurate Filtering of Privacy-Sensitive Information in Raw Genomic Data

Decouchant, J.; Fernandes, M.; Voelp, M.; M Couto, F.; Esteves-Verissimo, P.

10.1101/292185 — bioinformatics — Posted on 2018-03-30

105 Combining high resolution and exact calibration to boost statistical power: A well-calibrated score function for high-resolution MS2 data

Lin, A.; Howbert, J. J.; Noble, W.

10.1101/290858 — bioinformatics — Posted on 2018-03-30

106 Stroke survivors show task-dependent modulation of motor variability during bimanual coordination

Ranganathan, R.; Gebara, R.; Andary, M.; Sylvain, J.

10.1101/292193 — neuroscience — Posted on 2018-03-30

107 Human pathogenic bacterium Shigella infects Arabidopsis plants using type-III effectors that suppress conserved MAP kinase signaling

Jo, S. H.; Lee, J.; Kim, D. W.; Lee, D. H.; Ryu, C. M.; Park, J. M.

10.1101/292201 — microbiology — Posted on 2018-03-30

108 Rapid turnover of life-cycle-related genes in the brown algae

Lipinska, A. P.; Serrano-Serrano, M.; Peters, A. F.; Kogame, K.; Cock, J. M.; Coelho, S. M.

10.1101/290809 — evolutionary biology — Posted on 2018-03-30

109 GPRIN1 modulates neuronal signal transduction and affects mouse-learning behavior

Dioum, E. H. M.; Savoia, C.; Pujol, J. B.; Vaucher, A.; De Marchi, U.; Rieker, C.; Heikkilä, E.; Nunez Galindo, A.; Dayon, L.

10.1101/291377 — neuroscience — Posted on 2018-03-30

110 Dorsal Hippocampal Activation Suppresses Neuropathic Pain Behaviors: Chronic pain as extinction-resistant pain-related memory traces

Apkarian, A. V.; Wei, X.; Ren, W.; Centeno, M.; Procissi, D.; Xu, T.; Jabakhanji, R.; Martina, M.; Radulovic, J.; Surmeier, D.; Liu, X.

10.1101/292094 — neuroscience — Posted on 2018-03-30

111 Task activations produce spurious but systematic inflation of task functional connectivity estimates

Cole, M. W.; Ito, T.; Schultz, D.; Mill, R.; Chen, R.; Cocuzza, C.

10.1101/292045 — neuroscience — Posted on 2018-03-30

112 Spatial and Temporal Cortical Variability Track with Age and Affective Experience During Emotion Regulation in Youth

Guassi Moreira, J. F.; McLaughlin, K. A.; Silvers, J. A.

10.1101/291245 — neuroscience — Posted on 2018-03-30

113 Comparison of Genotypic and Phenotypic Correlations: Cheveruds Conjecture in Humans

Sodini, S. M.; Kemper, K. E.; Wray, N. R.; Trzaskowski, M.

10.1101/291062 — genetics — Posted on 2018-03-30

114 Age dependence of systemic bone loss and recovery following femur fracture in mice

Emami, A. J.; Toupadakis, C. A.; Telek, S. M.; Fyhrie, D. P.; Yellowley, C. E.; Christiansen, B. A.

10.1101/291906 — bioengineering — Posted on 2018-03-30

115 Response to Problems in interpreting and using GWAS of conditional phenotypes illustrated by alcohol GWAS

Clarke, T.-K.; McIntosh, A. M.

10.1101/290965 — genetics — Posted on 2018-03-30

116 HDAC11 Suppresses the Thermogenic Program of Adipose Tissue via BRD2

Bagchi, R. A.; Ferguson, B. S.; Stratton, M. S.; Hu, T.; Cavasin, M. A.; Sun, L.; Lin, Y.-H.; Liu, D.; Londono, P.; Song, K.; Pino, M. F.; Sparks, L. M.; Smith, S. R.; Scherer, P. E.; Collins, S.; Seto, E.; McKinsey, T. A.

10.1101/292011 — molecular biology — Posted on 2018-03-30

117 Modelling bacteria-phage interactions driving predation and horizontal gene transfer

Sousa, J. M. d.; Alsaadi, A.; Haaber, J.; Ingmer, H.; Rocha, E. P. C.

10.1101/291328 — microbiology — Posted on 2018-03-30

118 MinION sequencing enables rapid whole genome assembly of Rickettsia typhi in a resource-limited setting

Elliott, I.; Ming, D.; Robinson, M. T.; Nawtaisong, P.; Newton, P. N.; de Cesare, M.; Bowden, R.; Batty, E. M.

10.1101/292102 — genomics — Posted on 2018-03-30

119 Simultaneous detection of invasive signal crayfish, endangered white-clawed crayfish and the crayfish plague pathogen using environmental DNA

Robinson, C.; Uren-Webster, T.; Cable, J.; James, J.; Consuegra, S.

10.1101/291856 — ecology — Posted on 2018-03-30

120 Simulations and Electrostatic Analysis Suggest an Active Role for DNA Conformational Changes During Genome Packaging by Bacteriophages

Sharp, K. A.; Lu, X.-J.; Cingolani, G.; Harvey, S. C.

10.1101/288415 — biophysics — Posted on 2018-03-30

121 Bayesian Inference for a Generative Model of Transcriptome Profiles from Single-cell RNA Sequencing

Lopez, R.; Regier, J.; Cole, M. B.; Jordan, M.; Yosef, N.

10.1101/292037 — bioinformatics — Posted on 2018-03-30

122 DIMEdb: an integrated database and web service for metabolite identification in direct infusion mass spectrometery

O'Shea, K.; Kattupalli, D.; Mur, L. A.; Hardy, N. W.; Misra, B. B.; Lu, C.

10.1101/291799 — bioinformatics — Posted on 2018-03-30

123 Flux-dependent graphs for metabolic networks

Beguerisse-Diaz, M.; Bosque Chacon, G.; Oyarzun, D.; Pico, J.; Barahona, M.

10.1101/290767 — systems biology — Posted on 2018-03-30

124 Isw2 and Ino80 chromatin remodeling factors regulate chromatin, replication, and copy number at the yeast ribosomal DNA locus

Cutler, S.; Lee, L. J.; Tsukiyama, T.

10.1101/291971 — molecular biology — Posted on 2018-03-30

125 Lymphocyte activation gene 3 (Lag3) is upregulated by prions but does not contribute to disease

Liu, Y.; Sorce, S.; Nuvolone, M.; Domange, J.; Aguzzi, A.

10.1101/291401 — neuroscience — Posted on 2018-03-29

126 FIT2 is a lipid phosphate phosphatase crucial for endoplasmic reticulum homeostasis

Becuwe, M.; Bond, L. M.; Mejhert, N.; Boland, S.; Elliott, S. D.; Cicconet, M.; Liu, X. N.; Graham, M. M.; Walther, T. C.; Farese, R. V.

10.1101/291765 — cell biology — Posted on 2018-03-29

127 THE MITOCHONDRIAL DNA CONTROL REGION MIGHT HAVE USEFUL DIAGNOSTIC AND PROGNOSTIC BIOMARKERS FOR THYROID TUMORS

Bircan, R.; Iliksu Gozu, H.; Ulu, E.; Sarikaya, S.; Ege Gul, A.; Yasar Sirin, D.; Ozcelik, S.; Aral, C.

10.1101/291435 — cancer biology — Posted on 2018-03-29

128 Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children

Zinter, M. S.; Dvorak, C. C.; Mayday, M. Y.; Iwanaga, K.; Ly, N. P.; McGarry, M. E.; Church, G. D.; Faricy, L. E.; Rowan, C. M.; Hume, J. R.; Steiner, M. E.; Crawford, E. D.; Langelier, C.; Kalantar, K.; Chow, E. D.; Miller, S.; Shimano, K.; Melton, A.; Yanik, G. A.; Sapru, A.; DeRisi, J. L.

10.1101/291864 — microbiology — Posted on 2018-03-29

129 Coding and non-coding RNA dysregulation in bipolar disorder

Luykx, J.; Giuliani, F.; Giuliani, G.; Veldink, J.

10.1101/291385 — genetics — Posted on 2018-03-29

130 Emergent sub-population behavior uncovered with a community dynamic metabolic model of Escherichia coli diauxic growth

Succurro, A.; Segre, D.; Ebenhöh, O.

10.1101/291492 — systems biology — Posted on 2018-03-29

131 Automated classification of synaptic vesicles in electron tomograms of C. elegans using machine learning

Kaltdorf, K. V.; Theiss, M.; Markert, S.; Zhen, M.; Dandekar, T.; Stigloher, C.; Kollmannsberger, P.

10.1101/291310 — neuroscience — Posted on 2018-03-29

132 AutonoMouse: High throughput automated operant conditioning shows progressive behavioural impairment with graded olfactory bulb lesions.

Erskine, A.; Bus, T.; Herb, J. T.; Schaefer, A. T.

10.1101/291815 — neuroscience — Posted on 2018-03-29

133 Targeted Gene Bisulfite Sequencing Identifies Differential Methylation in p21

Cummings, B. S.; Kolli, R. T.; Glenn, T. C.; Brown, B. T.; Barnett, L. M.; Lash, L. H.

10.1101/291732 — molecular biology — Posted on 2018-03-29

134 Genomic normalization for sequencing libraries enrichment for rare somatic retroelement insertions

Komkov, A. Y.; Nugmanov, G. A.; Salutina, M. V.; Minervina, A. A.; Khodosevich, K. V.; Lebedev, Y. B.; Mamedov, I. Z.

10.1101/291773 — genomics — Posted on 2018-03-29

135 Relationships between estimated autozygosity and complex traits in the UK Biobank

Johnson, E. C.; Evans, L. M.; Keller, M. C.

10.1101/291872 — genetics — Posted on 2018-03-29

136 Fission yeast NDR/LATS kinase Orb6 regulates exocytosis via phosphorylation of exocyst complex

Tay, Y. D.; Leda, M.; Spanos, C.; Rappsilber, J.; Goryachev, A.; Sawin, K.

10.1101/291468 — cell biology — Posted on 2018-03-29

137 Cancer therapy with a CRISPR-assistant telomerase-activating gene expression system

Dai, W.; Xu, X.; Wang, D.; Wu, J.; Wang, J.

10.1101/291302 — cancer biology — Posted on 2018-03-29

138 Signal-to-Noise ratio made easy: A tool to assess your confocal performance

Ferrand, A.; Schleicher, K. D.; Ehrenfeuchter, N.; Heusermann, W.; Biehlmaier, O.

10.1101/291500 — biophysics — Posted on 2018-03-29

139 Locality Sensitive Imputation for Single-Cell RNA-Seq Data

Moussa, M.; Mandoiu, I.

10.1101/291807 — bioinformatics — Posted on 2018-03-29

140 A fungal ribonuclease-like effector protein inhibits plant host ribosomal RNA degradation

Spanu, P. D.; Pennington, H. G.; Jones, R.; Kwon, S.; Bonciani, G.; Thieron, H.; Chandler, T.; Luong, P.; Morgan, S.; Przydacz, M.; Bozkurt, T. O.; Bowden, S.; Craze, M.; Wallington, E.; Garnett, J.; Kwaitaal, M.; Panstruga, R.; Cota, E.

10.1101/291427 — plant biology — Posted on 2018-03-29

141 Direct nucleic acid analysis of mosquitoes for high fidelity species identification and detection of Wolbachia using a cellphone

Bhadra, S.; Riedel, T. E.; Saldana, M. A.; Hegde, S.; Pederson, N.; Hughes, G. L.; Ellington, A. D.

10.1101/291849 — molecular biology — Posted on 2018-03-29

142 Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking

Fauster, A.; Rebsamen, M.; Willmann, K. L.; Cesar-Razquin, A.; Girardi, E.; Bigenzahn, J. W.; Schischlik, F.; Scorzoni, S.; Bruckner, M.; Konecka, J.; Hörmann, K.; Heinz, L. X.; Boztug, K.; Superti-Furga, G.

10.1101/290718 — cell biology — Posted on 2018-03-29

143 Single-cell transcriptomic characterization of 20 organs and tissues from individual mice creates a Tabula Muris

The Tabula Muris Consortium, ; Quake, S. R.; Wyss-Coray, T.; Darmanis, S.

10.1101/237446 — cell biology — Posted on 2018-03-29

144 Climate-fire-vegetation interactions and the rise of novel landscape patterns in subalpine ecosystems, Colorado

Calder, W. J.; Stefanova, I.; Shuman, B. N.

10.1101/290163 — ecology — Posted on 2018-03-29

145 Branch-recombinant Gaussian processes for analysis of perturbations in biological time series

Penfold, C. A.; Sybirna, A.; Reid, J.; Huang, Y.; Wernisch, L.; Ghahramani, Z.; Grant, M.; Surani, M. A.

10.1101/291757 — bioinformatics — Posted on 2018-03-29

146 Monkeys are Curious about Counterfactual Outcomes

Wang, M. Z.; Hayden, B.

10.1101/291708 — animal behavior and cognition — Posted on 2018-03-29

147 A Quantitative Tractography Study into the Connectivity, Segmentation and Laterality of the Human Inferior Longitudinal Fasciculus

Panesar, S.; Yeh, F.-C.; Jacquesson, T.; Hula, W.; Fernandez-Miranda, J.

10.1101/291625 — neuroscience — Posted on 2018-03-29

148 Design and evaluation of a large sequence-capture probe set and associated SNPs for diploid and haploid samples of Norway spruce (Picea abies)

Vidalis, A.; Scofield, D. G.; Neves, L. G.; Bernhardsson, C.; Garcia-Gil, M. R.; Ingvarsson, P.

10.1101/291716 — genomics — Posted on 2018-03-29

149 A structural mechano-chemical model for dynamic instability of microtubule

Stewman, S.; Ma, A.

10.1101/291682 — cell biology — Posted on 2018-03-29

150 EPA-ng: Massively Parallel Evolutionary Placement of Genetic Sequences

Barbera, P.; Kozlov, A. M.; Czech, L.; Morel, B.; Stamatakis, A.

10.1101/291658 — bioinformatics — Posted on 2018-03-29

151 Using Single Nucleotide Variations in Single-Cell RNA-Seq to Identify Tumor Subpopulations and Genotype-phenotype Linkage

Poirion, O. B.; Zhu, X.; Ching, T.; Garmire, L. X.

10.1101/095810 — bioinformatics — Posted on 2018-03-29

152 Prediction of prostate cancer by deep learning with multilayer artificial neural network.

Takeuchi, T.; Hattori-Kato, M.; Okuno, Y.; Iwai, S.; Mikami, K.

10.1101/291609 — bioinformatics — Posted on 2018-03-29

153 Dosage sensitivity of X-linked genes in human embryonic single cells

Chen, X.; Yang, J.-R.

10.1101/291724 — genomics — Posted on 2018-03-29

154 Adult-specific pheromones differently influence malthusian escape strategies of younger generations

Werner, M. S.; Claassen, M.; Renahan, T.; Dardiry, M.; Sommer, R. J.

10.1101/291591 — ecology — Posted on 2018-03-29

155 Pisces: An Accurate and Versatile Variant Caller for Somatic and Germline Next-Generation Sequencing Data

Dunn, T.; Berry, G.; Emig-Agius, D.; Jiang, Y.; Lei, S.; Iyer, A.; Udar, N.; Chuang, H.-Y.; Hegarty, J.; Dickover, M.; Klotzle, B.; Robbins, J.; Bibikova, M.; Peeters, M.; Stromberg, M.

10.1101/291641 — bioinformatics — Posted on 2018-03-29

156 Jagged1/Notch2 Controls Kidney Fibrosis via Tfam-mediated Metabolic Reprogramming

Huang, S.; Park, J.; Qiu, C.; Sirin, Y.; Han, S. H.; Li, S.-y.; Taylor, V.; Zimber-Strobl, U.; Susztak, K.

10.1101/285726 — pathology — Posted on 2018-03-29

157 Chemicogenetic recruitment of specific interneurons suppresses seizure activity

Calin, A.; Stancu, M.; Zagrean, A.-M.; Jefferys, J.; Ilie, A.-S.; Akerman, C.

10.1101/291179 — neuroscience — Posted on 2018-03-29

158 Ecological Insights from the Evolutionary History of Microbial Innovations

Muscarella, M. E.; O'Dwyer, J. P.

10.1101/220939 — microbiology — Posted on 2018-03-29

159 Nonparametric Bayesian inference of transcriptional branching and recombination identifies regulators of early human germ cell development

Penfold, C. A.; Sybirna, A.; Reid, J.; Huang, Y.; Wernisch, L.; Ghahramani, Z.; Grant, M.; Surani, M. A.

10.1101/167684 — developmental biology — Posted on 2018-03-29

160 Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Bansal, M.; Peyton, M.; He, J.; Kaustagi, M.; Iyer, A.; Comb, M.; White, M.; Minna, J.; Califano, A.

10.1101/289603 — systems biology — Posted on 2018-03-29

161 Computation is concentrated in rich clubs of local cortical neurons

Faber, S. P.; Timme, N. M.; Beggs, J. M.; Newman, E. L.

10.1101/290981 — neuroscience — Posted on 2018-03-29

162 Bayesian adaptive stimulus selection for dissociating models of psychophysical data

Cooke, J. R. H.; Selen, L. P. J.; van Beers, R. J.; Medendorp, W. P.

10.1101/220590 — neuroscience — Posted on 2018-03-29

163 ESR1, WT1, WNT4, ATM and TERT loci are major contributors to uterine leiomyoma predisposition

Välimäki, N.; Kuisma, H.; Pasanen, A.; Heikinheimo, O.; Sjöberg, J.; Bützow, R.; Sarvilinna, N.; Heinonen, H.-R.; Tolvanen, J.; Bramante, S.; Tanskanen, T.; Auvinen, J.; Piltonen, T.; Alkodsi, A.; Lehtonen, R.; Kaasinen, E.; Palin, K.; Aaltonen, L. A.

10.1101/291237 — genomics — Posted on 2018-03-29

164 Two Active X-chromosomes Modulate the Growth, Pluripotency Exit and DNA Methylation Landscape of Mouse Naive Pluripotent Stem Cells through Different Pathways

Song, J.; Janiszewski, A.; Geest, N. D.; Vanheer, L.; Talon, I.; Oh, T.; Pasque, V.

10.1101/291450 — developmental biology — Posted on 2018-03-29

165 The anti-apoptosis ubiquitin E3 ligase XIAP promotes autophagosome-lysosome fusion during autophagy

Pötsch, I.; Ebner, P.; Deszcz, L.; Bachtrog, I.; Stephani, M.; Diaz, C. G.; Dagdas, Y.; Ikeda, F.

10.1101/291294 — cell biology — Posted on 2018-03-29

166 A Patient-Derived Cellular Model for Huntington Disease Reveals Phenotypes at Clinically Relevant CAG Lengths

Hung, C. L. K.; Maiuri, T.; Bowie, L.; Gottesman, R.; Son, S.; Falcone, M.; Giordano, J. V.; Mattis, V.; Lau, T.; Kwan, V.; Wheeler, V.; Schertzer, J.; Singh, K.; Truant, R.

10.1101/291575 — cell biology — Posted on 2018-03-29

167 Comment on \"Magnetosensitive neurons mediate geomagnetic orientation in Caenorhabditis elegans\"

Keays, D. A.; Landler, L.; Nimpf, S.; Nordmann, G.; Papadaki-Anastasopoulou, A.; Hochstoeger, T.

10.1101/165738 — neuroscience — Posted on 2018-03-29

168 New perspectives on multilocus ancestry informativeness

Tal, O.; Tran, T. D.

10.1101/273466 — genetics — Posted on 2018-03-29

169 Imaging the evolution of visual specializations in fungus gnats

Taylor, G. J.; Hall, S. A.; Gren, J. A.; Baird, E.

10.1101/290841 — evolutionary biology — Posted on 2018-03-29

170 An Epiblast Stem Cell derived multipotent progenitor population for axial extension

Edri, S.; Hayward, P.; Baillie-Johnson, P.; Steventon, B.; Martinez Arias, A.

10.1101/242461 — developmental biology — Posted on 2018-03-29

171 The Kendrick Modelling Platform: Language Abstractions and Tools for Epidemiology

Bui, M. A. T.; Papoulias, N.; Stinckwich, S.; Ziane, M.; Roche, B.

10.1101/289199 — epidemiology — Posted on 2018-03-29

172 No evidence for associations between men’s salivary testosterone and responses on the Intrasexual Competitiveness Scale

Torrance, J.; Hahn, A.; Kandrik, M.; DeBruine, L.; Jones, B.

10.1101/198424 — animal behavior and cognition — Posted on 2018-03-29

173 The perception of color and material in natural tasks

Brainard, D. H.; Cottaris, N. P.; Radonjic, A.

10.1101/288662 — neuroscience — Posted on 2018-03-29

174 Generally applicable transcriptome-wide analysis of translational efficiency using anota2seq

Oertlin, C.; Lorent, J.; Gandin, V.; Murie, C.; Masvidal, L.; Cargnello, M.; Furic, L.; Topisirovic, I.; Larsson, O.

10.1101/106922 — bioinformatics — Posted on 2018-03-29

175 A new threat identified in the use of SDHIs pesticides targeting the mitochondrial succinate dehydrogenase enzyme

Benit, P.; Bortoli, S.; Huc, L.; Schiff, M.; Gimenez-Roqueplo, A.-P.; Rak, M.; Gressens, P.; Favier, J.; Rustin, P.

10.1101/289058 — ecology — Posted on 2018-03-29

176 Low Perfusion Compartments in Glioblastoma Quantified by Advanced Magnetic Resonance Imaging: Correlation with Patient Survival

Li, C.; Yan, J.-L.; Torheim, T.; McLean, M. A.; Boonzaier, N. R.; Huang, Y.; Yuan, J.; Van Dijken, B. R. J.; Matys, T.; Markowetz, F.; Price, S. J.

10.1101/180521 — neuroscience — Posted on 2018-03-29

177 Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks

Leland, B. A.; Chen, A. C.; Zhao, A. Y.; Wharton, R. C.; King, M. C.

10.1101/213405 — genetics — Posted on 2018-03-29

178 The relative contribution of natural landscapes and human-mediated factors on the connectivity of a noxious invasive weed

Alvarado-Serrano, D. F.; Van Etten, M.; Chang, S.-M.; Baucom, R.

10.1101/054122 — evolutionary biology — Posted on 2018-03-29

179 INFERENCE OF CELL TYPE COMPOSITION FROM HUMAN BRAIN TRANSCRIPTOMIC DATASETS ILLUMINATES THE EFFECTS OF AGE, MANNER OF DEATH, DISSECTION, AND PSYCHIATRIC DIAGNOSIS

Hagenauer, M. H.; Schulmann, A.; Li, J. Z.; Vawter, M. P.; Walsh, D. M.; Thompson, R. C.; Turner, C. A.; Bunney, W. E.; Myers, R. M.; Barchas, J. D.; Schatzberg, A. F.; Watson, S. J.; Akil, H.

10.1101/089391 — bioinformatics — Posted on 2018-03-29

180 An experimental and computational framework to build a dynamic protein atlas of human cell division

Cai, Y.; Hossain, M. J.; Heriche, J.-K.; Politi, A. Z.; Walther, N.; Koch, B.; Wachsmuth, M.; Nijmeijer, B.; Kueblbeck, M.; Martinic Kavur, M.; Ladurner, R.; Peters, J.-M.; Ellenberg, J.

10.1101/227751 — systems biology — Posted on 2018-03-29

181 Estimating the functional dimensionality of neural representations

Ahlheim, C.; Love, B. C.

10.1101/232454 — neuroscience — Posted on 2018-03-29

182 Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons

Zak, J. D.; Grimaud, J.; Li, R.-c.; Li, C.-c.; Murthy, V. N.

10.1101/282731 — neuroscience — Posted on 2018-03-29

183 TrackSig: reconstructing evolutionary trajectories of mutation signature exposure

Rubanova, Y.; Shi, R.; Li, R.; Wintersinger, J.; Sahin, N.; Deshwar, A.; PCAWG-11 working group, ; Morris, Q.

10.1101/260471 — bioinformatics — Posted on 2018-03-29

184 Oscillatory dynamics of perceptual to conceptual transformations in the ventral visual pathway

Clarke, A.; Devereux, B. J.; Tyler, L. K.

10.1101/259127 — neuroscience — Posted on 2018-03-29

185 Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking

10.1101/290718 — cell biology — Posted on 2018-03-29

186 NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody dependent cellular cytotoxicity

Arora, G.; Hart, G. T.; Manzella-Lapeira, J.; Doritchamou, J. Y. A.; Narum, D. L.; Thomas, M.; Brzostowski, J.; Rajagopalan, S.; Doumbo, O. K.; Traore, B.; Miller, L.; Pierce, S. K.; Duffy, P.; Crompton, P. D.; Desai, S. A.; Long, E. O.

10.1101/291336 — immunology — Posted on 2018-03-29

187 National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB): Outline and Patient-Matching Technique

Kubo, S.; Noda, T.; Myojin, T.; Nishioka, Y.; Higashino, T.; Matsui, H.; Kato, G.; Imamura, T.

10.1101/280008 — epidemiology — Posted on 2018-03-29

188 The Healthy Pregnancy Research Program: Transforming Pregnancy Research Through a ResearchKit App

Radin, J. M.; Steinhubl, S. R.; Su, A. I.; Bhargava, H.; Greenberg, B.; Bot, B. M.; Doerr, M.; Topol, E. J.

10.1101/289371 — epidemiology — Posted on 2018-03-29

189 The Kendrick Modelling Platform: Language Abstractions and Tools for Epidemiology

Bui, M. A. T.; Papoulias, N.; Stinckwich, S.; Ziane, M.; Roche, B.

10.1101/289199 — epidemiology — Posted on 2018-03-29

190 Characterizing Subpopulations with Better Response to Treatment Using Observational Data - an Epilepsy Case Study

Ozery-Flato, M.; El-Hay, T.; Aharonov, R.; Parush-Shear-Yashuv, N.; Goldschmidt, Y.; Borghs, S.; Chan, J.; Haddad, N.; Pierre-Louis, B.; Kalilani, L.

10.1101/290585 — epidemiology — Posted on 2018-03-29

191 Socioeconomic status of indigenous peoples with active tuberculosis in Brazil: a principal components analysis

Freitas, L. P.; Souza-Santos, R.; Kolte, I. V.; Malacarne, J.; Basta, P. C.

10.1101/290668 — epidemiology — Posted on 2018-03-29

192 HERD IMMUNITY TO EBOLAVIRUSES IS NOT A REALISTIC TARGET FOR CURRENT VACCINATION STRATEGIES

Masterson, S. G.; Lobel, L.; Carroll, M. W.; Wass, M. N.; Michaelis, M.

10.1101/289249 — epidemiology — Posted on 2018-03-29

193 Chemicogenetic recruitment of specific interneurons suppresses seizure activity

Calin, A.; Stancu, M.; Zagrean, A.-M.; Jefferys, J.; Ilie, A.-S.; Akerman, C.

10.1101/291179 — neuroscience — Posted on 2018-03-29

194 Probing the Acyl Carrier Protein-Enzyme Interactions within Terminal Alkyne Biosynthetic Machinery

Su, M.; Zhu, X.; Zhang, W.

10.1101/291195 — bioengineering — Posted on 2018-03-29

195 IL-33 regulates gene expression in intestinal epithelial cells independently of its nuclear localization

He, Z.; Chen, L.; Furtado, G.; Lira, S.

10.1101/291039 — immunology — Posted on 2018-03-28

196 Untangling the role of selection and drift in population divergence via transcriptional network simulations: Extended analysis of Ghalambor et al. (2015)

Hoke, K.; Hughes, K. A.; Fischer, E. K.; Ghalambor, C. K.

10.1101/277830 — evolutionary biology — Posted on 2018-03-28

197 Role of noise and parametric variation in the dynamics of gene regulatory circuits

Kohar, V.; Lu, M.

10.1101/291153 — systems biology — Posted on 2018-03-28

198 Representation of Border, Velocity and Speed in the Goldfish Brain

Vinepinsky, E.; Perchik, S.; Ben-Shahar, O.; Donchin, O.; Segev, R.

10.1101/291013 — neuroscience — Posted on 2018-03-28

199 Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo

Ata, H.; Ekstrom, T. L.; Martinez-Galvez, G.; Mann, C. M.; Dvornikov, A. V.; Schaefbauer, K. J.; Ma, A. C.; Dobbs, D.; Clark, K. J.; Ekker, S. C.

10.1101/291187 — molecular biology — Posted on 2018-03-28

200 Intracellular signaling through the comRS system in Streptococcus mutans genetic competence

Underhill, S. A. M.; Shields, R. C.; Kaspar, J. R.; Haider, M.; Burne, R. A.; Hagen, S. J.

10.1101/291088 — microbiology — Posted on 2018-03-28

201 Optimizing bioreactor growth of the smallest eukaryote

Smallwood, C. R.; Hill, E. A.; Chrisler, W. B.; Brookreson, J. T.; Evans, J. E.

10.1101/291211 — cell biology — Posted on 2018-03-28

202 A new approach to design artificial 3D micro-niches with combined chemical, topographical and rheological cues

Stoecklin, C.; Yue, Z.; Chen, W. W.; de Mets, R.; Fong, E.; Studer, V.; Viasnoff, V.

10.1101/291104 — bioengineering — Posted on 2018-03-28

203 The lysine demethylase dKDM2 is non-essential for viability, but regulates circadian rhythms in Drosophila

Zheng, Y.; Xue, Y.; Ren, X.; Xie, X.-J.; Liu, M.; Jia, Y.; Li, X.; Niu, Y.; Ni, J.-Q.; Zhang, Y.; Ji, J.-Y.

10.1101/291070 — developmental biology — Posted on 2018-03-28

204 Entropic Forces Drive Clustering and Spatial Localization of Influenza A M2 During Viral Budding

Madsen, J. J.; Grime, J. M. A.; Rossman, J. S.; Voth, G. A.

10.1101/291120 — biophysics — Posted on 2018-03-28

205 Heavily and Fully Modified RNAs Guide Efficient SpyCas9-Mediated Genome Editing

Mir, A.; Alterman, J. F.; Hassler, M. R.; Debacker, A. J.; Hudgens, E.; Echeverria, D.; Brodsky, M. H.; Khvorova, A.; Watts, J. K.; Sontheimer, E. J.

10.1101/290999 — biochemistry — Posted on 2018-03-28

206 Multi omics comparison reveals metabolome biochemistry, not microbiome composition or gene expression, corresponds to elevated biogeochemical function in the hyporheic zone

Graham, E. B.; Crump, A. R.; Kennedy, D. W.; Arntzen, E.; Fansler, S.; Purvine, S. O.; Nicora, C. D.; Nelson, W.; TFAILY, M. M.; Stegen, J. C.

10.1101/291096 — molecular biology — Posted on 2018-03-28

207 A gate-and-switch model for head orientation behaviors in C. elegans

Ouellette, M.-H.; Desrochers, M.; Gheta, I.; Ramos, R.; Hendricks, M.

10.1101/291005 — neuroscience — Posted on 2018-03-28

208 Recurrent AIPL1 c.487C>T truncating variant in Leber Congenital Amaurosis: Support of pathogenicity and regional implications

Abdallah, M. O.; Koko, M.; Faisal, S.; Newport, M.; Ibrahim, M.

10.1101/290650 — genomics — Posted on 2018-03-28

209 Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease

Johnson, M. J.; Laoharawee, K.; Lahr, W. S.; Weber, B. R.; Moriarity, B. S.

10.1101/290973 — genomics — Posted on 2018-03-28

210 SCIΦ: Single-cell mutation identification via phylogenetic inference

Singer, J.; Kuipers, J.; Jahn, K.; Beerenwinkel, N.

10.1101/290908 — bioinformatics — Posted on 2018-03-28

211 The Impact Of Thigh And Shank Marker Quantity On Lower Extremity Kinematics Using A Constrained Model

Slater, A. A.; Hullfish, T. J.; Baxter, J. R.

10.1101/290890 — bioengineering — Posted on 2018-03-28

212 Functional signature of conversion in Mild Cognitive Impairment patients

Delli Pizzi, S.; Punzi, M.; Sensi, S. L.

10.1101/290783 — neuroscience — Posted on 2018-03-28

213 Opposing roles of endosomal innate immunity proteins IFITM3 and TLR7 in human metapneumovirus infection

McMichael, T. M.; Zhang, Y.; Kenney, A. D.; Zhang, L.; Lu, M.; Chemudupati, M.; Li, J.; Yount, J. S.

10.1101/290957 — immunology — Posted on 2018-03-28

214 Subnetwork-based prognostic biomarkers exhibit performance and robustness superior to gene-based biomarkers in breast cancer

Grzadkowski, M. R.; Haider, S.; Sendorek, D.; Boutros, P. C.

10.1101/290924 — bioinformatics — Posted on 2018-03-28

215 Plantarflexor Moment Arms Estimated From Tendon Excursion In Vivo Are Not Well Correlated With Geometric Measurements

Baxter, J. R.; Piazza, S. J.

10.1101/290916 — bioengineering — Posted on 2018-03-28

216 Functional Deficits are Explained by Plantarflexor Remodeling Following Achilles Tendon Rupture Repair: Preliminary Findings

Baxter, J.; Hullfish, T.; Chao, W.

10.1101/290833 — bioengineering — Posted on 2018-03-28

217 Computation is concentrated in rich clubs of local cortical neurons

Faber, S. P.; Timme, N. M.; Beggs, J. M.; Newman, E. L.

10.1101/290981 — neuroscience — Posted on 2018-03-28

218 Discovery of biased orientation of human DNA motif sequences affecting enhancer-promoter interactions and transcription of genes

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2018-03-28

219 Achilles Tendon Structure Differs Between Runners And Non-Runners Despite No Clinical Signs Or Symptoms Of Mid-Substance Tendinopathy

Hullfish, T. J.; Hagan, K. L.; Casey, E.; Baxter, J. R.

10.1101/290866 — bioengineering — Posted on 2018-03-28

220 How to control for confounds in decoding analyses of neuroimaging data

Snoek, L.; Miletic, S.; Scholte, H. S.

10.1101/290684 — neuroscience — Posted on 2018-03-28

221 Imaging the evolution of visual specializations in fungus gnats

Taylor, G. J.; Hall, S. A.; Gren, J. A.; Baird, E.

10.1101/290841 — evolutionary biology — Posted on 2018-03-28

222 Does deterministic coexistence theory matter in a finite world? Insights from serpentine annual plants

Schreiber, S.; Levine, J. M.; Godoy, O.; Kraft, N.; Hart, S.

10.1101/290882 — ecology — Posted on 2018-03-28

223 Towards a bioelectronic computer: A theoretical study of a multi-layer biomolecular computing system that can process electronic inputs

Dunn, K. E.; Trefzer, M. A.; Johnson, S.; Tyrrell, A. M.

10.1101/290775 — synthetic biology — Posted on 2018-03-28

224 Sustained High- and Low-Frequency Neural Responses to Visual Stimuli in Scalp EEG

Gerber, E. M.; Deouell, L. Y.

10.1101/290593 — neuroscience — Posted on 2018-03-28

225 Germline silencing of UASt depends on the piRNA pathway

Huang, Y.-C.; Moreno, H.; Row, S.; Jia, D.; Deng, W.-M.

10.1101/290726 — genetics — Posted on 2018-03-28

226 Cohort-based Smoothing Methods for Age-specific Contact Rates

Vandendijck, Y.; Camarda, C. G.; Hens, N.

10.1101/290551 — epidemiology — Posted on 2018-03-28

227 Inducible alpha-synuclein overexpression affects human Neural Stem Cells behavior

Zasso, J.; Ahmed, M.; Cutarelli, A.; Conti, L.

10.1101/290619 — neuroscience — Posted on 2018-03-28

228 Responsiveness Of Dentate Neurons Generated Throughout Adult Life Determines Spatial Memory Ability Of Aged Rats

Montaron, M.-F.; Garcia, P.; Abrous, D. N.

10.1101/290676 — neuroscience — Posted on 2018-03-28

229 Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria.

Day, F.; Karaderi, T.; Jones, M. R.; Meun, C.; He, C.; Drong, A.; Kraft, P.; Lin, N.; Huang, H.; Broer, L.; Magi, R.; Saxena, R.; Laisk-Podar, T.; Urbanek, M.; Hayes, G. M.; Thorleifsson, G.; Fernandez-Tajes, J.; Mahajan, A.; Mullin, B. H.; Stuckey, B. G. A.; Spector, T. D.; Wilson, S. G.; Goodarzi, M. O.; Davis, L.; Obermeyer-Pietsch, B.; Uitterlinden, A. G.; Anttila, V.; Neale, B. M.; Jarvelin, M.-R.; Fauser, B.; Kowalska, I.; Visser, J. A.; Anderson, M.; Ong, K.; Stener-Victorin, E.; Ehrmann, D.; Legro, R. S.; Salumets, A.; McCarthy, M. I.; Morin-Papunen, L.; Thorsteinsdottir, U.; Stefansso

10.1101/290502 — genetics — Posted on 2018-03-28

230 Fast calcium transients in neuronal spines is driven by extreme statistics

Basnayake, K.; Korkotian, E.; Holcman, D.

10.1101/290734 — cell biology — Posted on 2018-03-28

231 Cell membranes resist flow

Shi, Z.; Graber, Z. T.; Baumgart, T.; Stone, H. A.; Cohen, A. E.

10.1101/290643 — biophysics — Posted on 2018-03-28

232 Functional and Early Folding Residues are separated in proteins to increase evolvability and robustness

Bittrich, S.; Schroeder, M.; Labudde, D.

10.1101/290627 — bioinformatics — Posted on 2018-03-28

233 Monkeys use the rod-dense retinal region rather than the fovea to visually fixate small targets in scotopic vision

Spivak, O.; Thier, P.; Barash, S.

10.1101/290759 — neuroscience — Posted on 2018-03-28

234 The changing landscape of VREfm in Victoria, Australia: a state-wide genomic snapshot

Lee, R. S.; Goncalves da Silva, A.; Baines, S. L.; Strachan, J.; Ballard, S.; Carter, G. P.; Kwong, J. C.; Schultz, M.; Bulach, D.; Seemann, T.; Stinear, T.; Howden, B. P.

10.1101/289975 — genomics — Posted on 2018-03-28

235 Standardized microgel beads as elastic cell mechanical probes

Girardo, S.; Traeber, N.; Wagner, K.; Cojoc, G.; Herold, C.; Goswami, R.; Schluessler, R.; Abuhattum, S.; Taubenberger, A.; Reichel, F.; Mokbel, D.; Herbig, M.; Schuermann, M.; Mueller, P.; Heida, T.; Jacobi, A.; Thiele, J.; Werner, C.; Guck, J.

10.1101/290569 — biophysics — Posted on 2018-03-28

236 The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein

Fontaine, K. A.; Leon, K. E.; Khalid, M. M.; Jimenez-Morales, D.; Kaye, J.; Shah, P.; Finkbeiner, S.; Krogan, N.; Ott, M.

10.1101/290296 — microbiology — Posted on 2018-03-28

237 Genome-wide patterns of local adaptation in Drosophila melanogaster: adding intra European variability to the map

Mateo, L.; Rech, G.; Gonzalez, J.

10.1101/269332 — evolutionary biology — Posted on 2018-03-28

238 Condition-adaptive fused graphical lasso (CFGL): an adaptive procedure for inferring condition-specific gene co-expression network

Lyu, Y.; Xue, L.; Zhang, F.; Koch, H.; Saba, L.; Kechris, K.; Li, Q.

10.1101/290346 — bioinformatics — Posted on 2018-03-28

239 Effect of visual cues in addition to moderate auditory cues on temporal coordination: A comparative study in humans and chimpanzees

Yu, L.; Tomonaga, M.

10.1101/290379 — animal behavior and cognition — Posted on 2018-03-28

240 Quantification of Phase-Amplitude Coupling in Neuronal Oscillations: Comparison of Phase-Locking Value, Mean Vector Length, and Modulation Index

Huelsemann, M. J.; Naumann, E.; Rasch, B.

10.1101/290361 — neuroscience — Posted on 2018-03-28

241 In vivo characterization and quantification of neurofibrillary tau PET radioligand [18F]MK-6240 in humans from Alzheimer’s disease dementia to young controls

Betthauser, T. J.; Cody, K. A.; Zammit, M. D.; Murali, D.; Converse, A. K.; Barnhart, T. E.; Stone, C. K.; Rowley, H. A.; Johnson, S. C.; Christian, B. T.

10.1101/290064 — neuroscience — Posted on 2018-03-28

242 Tasman-PCR: A genetic diagnostic assay for Tasmanian devil facial tumour diseases

Kwon, Y.; Stammnitz, M. R.; Wang, J.; Knowles, G. W.; Pye, R. J.; Hamede, R.; Murchison, E. P.

10.1101/287847 — genetics — Posted on 2018-03-28

243 Climate change and the potential distribution of Xylella fastidiosa in Europe

Godefroid, M.; Cruaud, A.; Streito, J.-C.; Rasplus, J.-Y.; Rossi, J.-P.

10.1101/289876 — ecology — Posted on 2018-03-28

244 Visualizing structure-mediated interactions in supercoiled DNA molecules

Scott, S.; Xu, Z. M.; Kouzine, F.; Berard, D. J.; Shaheen, C.; Gravel, B.; Saunders, L.; Hofkirchner, A.; Leroux, C.; Laurin, J.; Levens, D.; Benham, C. J.; Leslie, S. R.

10.1101/257949 — biophysics — Posted on 2018-03-28

245 An analysis of current state of the art software on nanopore metagenomic data

Pendleton, S. C.

10.1101/288969 — bioinformatics — Posted on 2018-03-28

246 Identification of Gene Regulation Models from Single-Cell Data

Weber, L.; Raymond, W.; Munsky, B.

10.1101/231415 — systems biology — Posted on 2018-03-28

247 Quantitative characterization of translational riboregulators using an in vitro transcription-translation system

Senoussi, A.; Lee Tin Wah, J.; Shimizu, Y.; Robert, J.; Jaramillo, A.; Findeiss, S.; Axmann, I. M.; Estevez-Torres, A.

10.1101/290403 — synthetic biology — Posted on 2018-03-28

248 The functional brain organization of an individual predicts measures of social abilities in autism spectrum disorder

Lake, E. M. R.; Finn, E. S.; Noble, S. M.; Vanderwal, T.; Shen, X.; Rosenberg, M. D.; Spann, M. N.; Chun, M. M.; Scheinost, D.; Constable, R. T.

10.1101/290320 — neuroscience — Posted on 2018-03-28

249 Changes in the genetic requirements for microbial interactions with increasing community complexity

Morin, M.; Pierce, E. C.; Dutton, R. J.

10.1101/290353 — microbiology — Posted on 2018-03-28

250 Parasitism effects on coexistence and stability within simple trophic modules

Prosnier, L.; Medoc, V.; Loeuille, N.

10.1101/289819 — ecology — Posted on 2018-03-28

251 Profiling copy number alterations in cell-free tumour DNA using a single-reference

Robertson, A.; Xu, Q.; Song, S.; Ganesamoorthy, D.; Benson, D.; Chen, W.; Ferguson, K.; Nones, K.; Lakhani, S. R.; Simpson, P. T.; Waddell, N.; Pearson, J.; Coin, L.

10.1101/290171 — bioinformatics — Posted on 2018-03-28

252 Complete guide RNA design for CRISPR-mediated regulation of human long noncoding RNA transcription

Saberi, A.; Zhu, R.; Kwon, C.

10.1101/290338 — bioengineering — Posted on 2018-03-28

253 A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities

Hoyt, C. T.; Domingo-Fernandez, D.; Balzer (Filep), N. R.; Gueldenpfennig, A.; Hofmann-Apitius, M.

10.1101/269860 — systems biology — Posted on 2018-03-28

254 Distal Radius Microstructure and Finite Element Bone Strain Are Related to Site-Specific Mechanical Loading and Areal Bone Mineral Density in Premenopausal Women

Mancuso, M. E.; Johnson, J. E.; Ahmed, S. S.; Butler, T. A.; Troy, K. L.

10.1101/146258 — physiology — Posted on 2018-03-28

255 Experimental Evidence That Thermal Selection Shapes Mitochondrial Genome Evolution

Lajbner, Z.; Pnini, R.; Camus, M. F.; Miller, J.; Dowling, D. K.

10.1101/133389 — evolutionary biology — Posted on 2018-03-28

256 A drug-tunable gene therapy for broad-spectrum protection against retinal degeneration

Santiago, C. P.; Keuthan, C. J.; Boye, S.; Boye, S.; Imam, A. A.; Ash, J. D.

10.1101/283887 — bioengineering — Posted on 2018-03-28

257 SAFE-clustering: Single-cell Aggregated (From Ensemble) Clustering for Single-cell RNA-seq Data

Yang, Y.; Huh, R.; Culpepper, H. W.; Lin, Y.; Love, M. I.; Li, Y.

10.1101/215723 — bioinformatics — Posted on 2018-03-28

258 Label-free prediction of three-dimensional fluorescence images from transmitted light microscopy

Ounkomol, C.; Seshamani, S.; Maleckar, M. M.; Collman, F.; Johnson, G.

10.1101/289504 — cell biology — Posted on 2018-03-28

259 Motor Responses Influence Perceptual Awareness Judgements

Siedlecka, M.; Hobot, J.; Skora, Z.; Paulewicz, B.; Timmermans, B.; Wierzchon, M.

10.1101/283762 — animal behavior and cognition — Posted on 2018-03-28

260 A (blue) light in the dark: Blue light modulates oscillatory alpha activity in the occipital cortex of totally visually blind individuals with intact non-visual photoreception

Vandewalle, G.; van Ackeren, M. J.; Daneault, V.; Hull, J. T.; Albouy, G.; Lepore, F.; Doyon, J.; Czeisler, C. A.; Dumont, M.; Carrier, J.; Lockley, S. W.; Collignon, O.

10.1101/175851 — neuroscience — Posted on 2018-03-28

Meier, M. L.; Humphreys, B. K.; Vrana, A.; Seifritz, E.; Staempfli, P.; Schweinhardt, P.

10.1101/251751 — neuroscience — Posted on 2018-03-28

262 Metabolic adaptations underlie epigenetic vulnerabilities in chemoresistant breast cancer.

Deblois, G.; Madani Tonekaboni, S. A.; Kao, Y.; Tai, F.; Liu, X.; Ettayebi, I.; Grillo, G.; Guilhamon, P.; Ba-alawi, W.; Fedor, A.; Murison, A.; Cescon, D.; Arrowsmith, C.; DeCarvalho, D.; Park, M.; Haibe-Kains, B.; Locasale, J. W.; Lupien, M.

10.1101/286054 — genomics — Posted on 2018-03-28

263 Evolution of the D. melanogaster chromatin landscape and its associated proteins

Parey, E.; Crombach, A.

10.1101/284828 — evolutionary biology — Posted on 2018-03-28

264 Assessing the durability and efficiency of landscape-based strategies to deploy plant resistance to pathogens

Rimbaud, L.; Papaïx, J.; Rey, J.-F.; Barrett, L. G.; Thrall, P. H.

10.1101/260836 — evolutionary biology — Posted on 2018-03-28

265 A blood-based signature of cerebral spinal fluid Aβ1-42 status

Goudey, B.; Fung, B. J.; Schieber, C.; Faux, N. G.

10.1101/190207 — neuroscience — Posted on 2018-03-28

266 Understanding the limit of open search in the identification of peptides with post-translational modifications -- A simulation-based study

Dai, J.; Yu, F.; Li, N.; Yu, W.

10.1101/289710 — bioinformatics — Posted on 2018-03-28

267 A translaminar genetic logic for the circuit identity of intracortically-projecting neurons

Klingler, E.; De la Rossa, A.; Fievre, S.; Jabaudon, D.

10.1101/290395 — neuroscience — Posted on 2018-03-28

268 Female ornamentation and the fecundity trade-off in a sex-role reversed pipefish

Mobley, K. B.; Morrongiello, J. R.; Warr, M.; Bray, D.; Wong, B. B. M.

10.1101/290387 — evolutionary biology — Posted on 2018-03-28

269 Hemolysin liberates bacterial outer membrane vesicles for cytosolic lipopolysaccharide sensing

Liu, Q.; Chen, S.; Yang, D.; Wen, Y.; Jiang, Z.; Zhang, L.; Jiang, J.; Chen, Y.; Hu, T.; Wang, Q.; Zhang, Y.

10.1101/290445 — immunology — Posted on 2018-03-28

270 De novo transcriptome assembly, annotation, and identification of low-copy number genes in the flowering plant genus Silene (Caryophyllaceae)

Bertrand, Y. J.; Petri, A.; Scheen, A.-C.; Topel, M.; Oxelman, B.

10.1101/290510 — bioinformatics — Posted on 2018-03-28

271 Wide distributions and cryptic diversity within a Microstomum (Platyhelminthes) species complex

Atherton, S.; Jondelius, U.

10.1101/290429 — zoology — Posted on 2018-03-28

272 Identification of microRNA clusters cooperatively acting on Epithelial to Mesenchymal Transition in Triple Negative Breast Cancer

Cantini, L.; Bertoli, G.; Cava, C.; Dubois, T.; Zinovyev, A.; Caselle, M.; Castiglioni, I.; Barillot, E.; Martignetti, L.

10.1101/290528 — systems biology — Posted on 2018-03-28

273 The action of a cosmetic hair treatment on follicle function

Turner, G. A.; Paterson, S. E.; Baines, F. L.; Mayes, A. E.; Reilly, D. M.; Hudson, N. M.; Dadd, T.; Majumdar, A.; Kapoor, R.; Gu, J.; Bhalla, N.; Xu, F.

10.1101/290437 — physiology — Posted on 2018-03-28

274 Structure of the herpes-simplex virus portal-vertex

McElwee, M.; Vijayakrishnan, S.; Rixon, F.; Bhella, D.

10.1101/290544 — microbiology — Posted on 2018-03-28

275 Interhomolog polymorphism shapes meiotic crossover within RAC1 and RPP13 disease resistance genes

Serra, H.; Choi, K.; Zhao, X.; Blackwell, A.; Henderson, I.

10.1101/290478 — genetics — Posted on 2018-03-28

276 Adaptive harvesting drives fishing down processes, regime shifts, and resilience changes in predator-prey systems

Tromeur, E.; Loeuille, N.

10.1101/290460 — ecology — Posted on 2018-03-28

277 ERBB2 and KRAS Alterations Mediate Response to EGFR Inhibitors in early stage Gallbladder Cancer

Iyer, P.; Shrikhande, S. V.; Ranjan, M.; Joshi, A.; Prasad, R.; Gardi, N.; Thorat, R.; Salunkhe, S.; Dharavath, B.; Sahoo, B.; Chandrani, P.; Kore, H.; Mohanty, B.; Chaudhari, V.; Choughule, A.; Kawle, D.; Chaudhari, P.; Ingle, A.; Banavali, S.; Ramadwar, M. R.; Prabhash, K.; Barreto, S. G.; Dutt, S.; Dutt, A.

10.1101/290486 — cancer biology — Posted on 2018-03-28

278 Ameliorative potential of curcumin on cigarette smoke extract induced cognitive impairment in zebrafish

Thilagavathi, L.; Jabeen, S.; Ravishankar, S. B.; Ahmed, S. S.; George, T.; Rishitha, N.; Muthuraman, A.; Paramakrishnan, N.

10.1101/290536 — animal behavior and cognition — Posted on 2018-03-28

279 Brain-Specific Deletion of GIT1 Impairs Cognition and Alters Phosphorylation of Synaptic Protein Networks Implicated in Schizophrenia Susceptibility

Fass, D. M.; Lewis, M. C.; Ahmad, R.; Szucs, M. J.; Zhang, Q.; Fleishman, M.; Wang, D.; Kim, M. J.; Biag, J.; Carr, S. A.; Scolnick, E. M.; Premont, R. T.; Haggarty, S. J.

10.1101/290312 — neuroscience — Posted on 2018-03-27

280 Benefits And Limitations Of Three-Dimensional Printing Technology For Ecological Research

Behm, J.; Waite, B. R.; Hsieh, S. T.; Helmus, M. R.

10.1101/283895 — ecology — Posted on 2018-03-27

281 Inference of Species Phylogenies from Bi-allelic Markers Using Pseudo-likelihood

Zhu, J.; Nakhleh, L.

10.1101/289207 — evolutionary biology — Posted on 2018-03-27

282 Comparable affinity of RabGDIα for GTP- and GDP-bound forms of Rab7 supports a four-state transition model for Rab7 subcellular localization

Kanemitsu, A. F.; Morishita, S.; Kjaer, S.; Fukuda, M.; Schiavo, G.; Nakamura, T.

10.1101/287516 — cell biology — Posted on 2018-03-27

283 Dissociable Roles for Working Memory in Sensorimotor Learning

McDougle, S. D.; Taylor, J. A.

10.1101/290189 — neuroscience — Posted on 2018-03-27

284 Climate-fire-vegetation interactions and the rise of novel landscape patterns in subalpine ecosystems, Colorado

Calder, W. J.; Stefanova, I.; Shuman, B. N.

10.1101/290163 — ecology — Posted on 2018-03-27

285 Mass Amphibian Mortality during Overwintering Related To Fungal Pathogen But Not Larval Environment: An Explanation for Declines?

Rumschlag, S. L.; Boone, M. D.

10.1101/290213 — ecology — Posted on 2018-03-27

286 A novel cell segmentation method for developing embryos using machine learning

Ota, R.; Ide, T.; Michiue, T.

10.1101/288720 — developmental biology — Posted on 2018-03-27

287 Asymmetrically Positioned Flagellar Control Units Regulate Human Sperm Rotation

Miller, M.; Kenny, S.; Mannowetz, N.; Mansell, S.; Wojcik, M.; Mendoza, S.; Zucker, R.; Xu, K.; Lishko, P. V.

10.1101/290122 — cell biology — Posted on 2018-03-27

288 A simple and robust procedure for preparing graphene-oxide cryo-EM grids

Palovcak, E.; Wang, F.; Zheng, S. Q.; Yu, Z.; Li, S.; Bulkley, D.; Agard, D. A.; Cheng, Y.

10.1101/290197 — biophysics — Posted on 2018-03-27

289 dtangle: accurate and fast cell-type deconvolution

Hunt, G. J.; Freytag, S.; Bahlo, M.; Gagnon-Bartsch, J. A.

10.1101/290262 — bioinformatics — Posted on 2018-03-27

290 Host Diet Influences Lethal and Sublethal Responses of Hosts to Amphibian Pathogen Exposure

Rumschlag, S. L.; Boone, M. D.

10.1101/290239 — ecology — Posted on 2018-03-27

291 Characterizing Genetic Circuit Components in E. coli towards a Campylobacter jejuni Biosensor.

Brzozowska, N.; Gourlay, J.; O'Sullivan, A.; Buchanan, F.; Hannah, R.; Stewart, A.; Taylor, H.; Docea, R.; McLay, G.; Giuliano, A.; Provan, J.; Baker, K.; Abioye, J.; Reboud, J.; Colloms, S.

10.1101/290155 — synthetic biology — Posted on 2018-03-27

292 Numerous recursive sites contribute to accuracy of splicing of long introns in flies

Pai, A. A.; Paggi, J.; Adelman, K.; Burge, C. B.

10.1101/290007 — genomics — Posted on 2018-03-27

293 G2P: Using machine learning to understand and predict genes causing rare neurological disorders

Botia, J. A.; Guelfi, S.; Zhang, D.; D'Sa, K.; Reinolds, R.; Onah, D.; McDonagh, E. M.; Rueda-Martin, A.; Tucci, A.; Rendon, A.; Houlden, H.; Hardy, J.; Ryten, M.

10.1101/288845 — genetics — Posted on 2018-03-27

294 Contrasting patterns of coding and flanking region evolution in mammalian keratin associated protein-1 genes

Zhou, H.; Visnovska, T.; Gong, H.; Schmeier, S.; Hickford, J.; Ganley, A. R. D.

10.1101/282418 — evolutionary biology — Posted on 2018-03-27

295 Multiple Determinants and Consequences of Cohesion Fatigue in Mammalian Cells

Sapkota, H.; Wasiak, E.; Gorbsky, G. J.

10.1101/240630 — cell biology — Posted on 2018-03-27

296 CaMK (CMK-1) and O-GlcNAc transferase (OGT-1) modulate mechanosensory responding and habituation in an interstimulus interval-dependent manner in Caenorhabditis elegans

Ardiel, E. L.; McDiarmid, T. A.; Timbers, T. A.; Lee, K.; Safaei, J.; Pelech, S. L.; Rankin, C. H.

10.1101/115972 — animal behavior and cognition — Posted on 2018-03-27

297 A novel mutual information estimator to measure spike train correlations in a model thalamocortical network

Gribkova, E. D.; Ibrahim, B. A.; Llano, D. A.

10.1101/289512 — neuroscience — Posted on 2018-03-27

298 Microstate EEGlab toolbox: An introductory guide

Poulsen, A. T.; Pedroni, A.; Langer, N.; Hansen, L. K.

10.1101/289850 — neuroscience — Posted on 2018-03-27

299 MRI2MRI: A deep convolutional network that accurately transforms between brain MRI contrasts

Xiao, S.; Wu, Y.; Lee, A. Y.; Rokem, A.

10.1101/289926 — neuroscience — Posted on 2018-03-27

300 Sexual reproduction in the fungal foliar pathogen Zymoseptoria tritici is driven by antagonistic density-dependence mechanisms

Suffert, F.; Delestre, G.; Gelisse, S.

10.1101/290072 — microbiology — Posted on 2018-03-27

301 Understanding the limit of open search in the identification of peptides with post-translational modifications -- A simulation-based study

Dai, J.; Yu, F.; Li, N.; Yu, W.

10.1101/289710 — bioinformatics — Posted on 2018-03-27

302 Controlling false discoveries in Bayesian gene networks with lasso regression p-values

Wang, L.; Michoel, T.

10.1101/288217 — systems biology — Posted on 2018-03-27

303 Cortical thickness in right frontal and left lingual gyri differentially mediate episodic memory for spatial contextual details across the adult lifespan

Swierkot, A.; Rajah, M. N.

10.1101/289447 — neuroscience — Posted on 2018-03-27

304 Memory encoding of syntactic information involves domain-general attentional resources. Evidence from dual-task studies

Heyselaar, E.; Segaert, K.

10.1101/285411 — neuroscience — Posted on 2018-03-27

305 Brainwide organization of neuronal activity and convergent sensorimotor transformations in larval zebrafish

Chen, X.; Mu, Y.; Hu, Y.; Kuan, A. T.; Nikitchenko, M.; Randlett, O.; Sompolinsky, H.; Engert, F.; Ahrens, M. B.

10.1101/289413 — neuroscience — Posted on 2018-03-27

306 All-optical electrophysiology for high-throughput functional characterization of human iPSC-derived motor neuron model of ALS

Kiskinis, E.; Kralj, J. M.; Zou, P.; Weinstein, E. N.; Zhang, H.; Tsioras, K.; Wiskow, O.; Ortega, J. A.; Eggan, K.; Cohen, A. E.

10.1101/289959 — neuroscience — Posted on 2018-03-27

307 Hampered motility promotes the evolution of wrinkly phenotype in Bacillus subtilis

Richter, A.; Holscher, T.; Pausch, P.; Sehrt, T.; Brockhaus, F.; Bange, G.; Kovacs, A. T.

10.1101/288951 — microbiology — Posted on 2018-03-27

308 C. elegans avoidance of Pseudomonas: thioredoxin shapes the sensory response to bacterially produced nitric oxide

Kaplan, J. M.; Hall, Q.; Zhang, Y.; Hao, Y.; Yang, W.; Ren, J.

10.1101/289827 — microbiology — Posted on 2018-03-27

309 PGP-UK: a research and citizen science hybrid project in support of personalized medicine

Beck, S.; Berner, A. M.; Bignell, G.; Bond, M.; Callanan, M. J.; Chervova, O.; Conde, L.; Corpas, M.; Ecker, S.; Elliott, H. R.; Fioramonti, S. A.; Flanagan, A. M.; Gaentzsch, R.; Graham, D.; Gribbin, D.; Guerra-Assuncao, J. A.; Hamoudi, R.; Harding, V.; Harrison, P. L.; Herrero, J.; Hofmann, J.; Jones, E.; Khan, S.; Kaye, J.; Kerr, P.; Libertini, E.; McCormack, L.; Moghul, I.; Pontikos, N.; Rajanayagam, S.; Rana, K.; Semega-Janneh, M.; Smith, C. P.; Strom, L.; Urmur, S.; Webster, A. P.; Wint, K.; Wood, J. N.

10.1101/288829 — genomics — Posted on 2018-03-27

310 Genomic characterization of six virus-associated cancers identifies changes in the tumor microenvironment and altered genetic programming

Varn, F. S.; Wang, Y.; Cheng, C.

10.1101/289900 — cancer biology — Posted on 2018-03-27

311 Adjutant: an R-based tool to support topic discovery for systematic and literature reviews

Crisan, A.; Munzner, T.; Gardy, J. L.

10.1101/290031 — bioinformatics — Posted on 2018-03-27

312 The genetic basis of the human-cannabis relationship

Henry, P.

10.1101/287938 — animal behavior and cognition — Posted on 2018-03-27

313 Logical modelling and analysis of cellular regulatory networks with GINsim 3.0

Naldi, A.; Hernandez, C.; Abou-Jaoude, W.; Monteiro, P. T.; Chaouiya, C.; Thieffry, D.

10.1101/289298 — systems biology — Posted on 2018-03-27

314 Current production as a rapid response expression reporter under micro-oxic and anoxic conditions

Madsen, C. S.; Barvo, N. N.; Fromwiller, C.; Tyll, S.; Amburn, B.; Ducat, D.; Hamberger, B.; TerAvest, M. A.

10.1101/289140 — synthetic biology — Posted on 2018-03-27

315 Comparing methanol-glucose and dimethyl-sulfoxide based extender for milt cryopreservation of brown trout (Salmo trutta)

Nusbaumer, D.; Marques da Cunha, L.; Wedekind, C.

10.1101/289736 — physiology — Posted on 2018-03-27

316 Processing of Auditory Novelty Across the Cortical Hierarchy: An Intracranial Electrophysiology Study

Nourski, K. V.; Steinschneider, M.; Rhone, A. E.; Kawasaki, H.; Howard, M. A.; Banks, M. I.

10.1101/290106 — neuroscience — Posted on 2018-03-27

317 A Comparative Assessment of Human and Chimpanzee iPSC-derived Cardiomyocytes with Primary Heart Tissues

Pavlovic, B. J.; Blake, L. E.; Roux, J.; Chavarria, C.; Gilad, Y.

10.1101/289942 — genomics — Posted on 2018-03-27

318 Metagenomic assembly of new (sub)arctic Cyanobacteria and their associated microbiome from non-axenic cultures

Cornet, L.; Bertrand, A. R.; Hanikenne, M.; Javaux, E. J.; Wilmotte, A.; Baurain, D.

10.1101/287730 — genomics — Posted on 2018-03-27

319 Predicting the viability of archaic human hybrids using a mitochondrial proxy

Allen, R.; Ryan, H.; Davis, B.; Barnett, R.; Linderholm, A.; Loog, L.; Lebrasseur, O.; Frantz, L.; King, C.; White, M.; Murphy, W.; Haile, J.; Kitchener, A.; Larson, G.

10.1101/289892 — evolutionary biology — Posted on 2018-03-27

320 Differences between the de novo proteome and its non-functional precursor can result from neutral constraints on its birth process, not necessarily from natural selection alone

Nielly-Thibault, L.; Landry, C. R.

10.1101/289330 — evolutionary biology — Posted on 2018-03-27

321 TBtools, a Toolkit for Biologists integrating various HTS-data handling tools with a user-friendly interface

Chen, C.; Xia, R.; Chen, H.; He, Y.

10.1101/289660 — bioinformatics — Posted on 2018-03-27

322 DSeg: A dynamic image segmentation program to extract backbone patterns for filamentous bacteria and hyphae structures

Zhang, H.; Soderholm, N.; Sandblad, L.; Wiklund, K.; Andersson, M.

10.1101/289652 — bioinformatics — Posted on 2018-03-27

323 Systematic Elucidation and Validation of OncoProtein-Centric Molecular Interaction Maps

Broyde, J.; Simpson, D. R.; Murray, D.; Giorgi, F. M.; Lachmann, A.; Jackson, P. K.; Sweet-Cordero, E. A.; Honig, B.; Califano, A.

10.1101/289538 — systems biology — Posted on 2018-03-27

324 Apparent oxygen half saturation constant for nitrifiers: genus specific, inherent physiological property, or artefact of colony morphology?

Law, Y.; Matysik, A.; Chen, X.; Swa Thi, S.; Nguyen, T. Q. N.; Qiu, G. L.; Natarajan, G.; Williams, R. B. H.; Ni, B.-J.; Seviour, T. W.; Wuertz, S.

10.1101/289645 — systems biology — Posted on 2018-03-27

325 A novel, biologically-informed polygenic score reveals role of mesocorticolimbic insulin receptor gene network on impulsivity and addiction

McCracken, K.; Hari Dass, S. A.; Pokhvisneva, I.; Chen, L. M.; Garg, E.; Nguyen, T. T.; Yaqubi, M.; McEwen, L. M.; MacIsaac, J. L.; Diorio, J.; Kobor, M. S.; O'Donnell, K. J.; Meaney, M. J.; Silveira, P.

10.1101/289983 — neuroscience — Posted on 2018-03-27

326 Not so sterile after all: The endomicrobiome of plerocercoids of the cestode parasite Schistocephalus solidus and changes to the microbiome of its Threespine Stickleback host

Hahn, M. A.; Dheilly, N. M.

10.1101/290015 — microbiology — Posted on 2018-03-27

327 Ecological and evolutionary consequences of viral plasticity

Choua, M.; Bonachela, J.

10.1101/289116 — microbiology — Posted on 2018-03-27

328 Modern spandrels: The roles of genetic drift, gene flow and natural selection in the formation of parallel clines

Santangelo, J. S.; Johnson, M. T. J.; Ness, R. W.

10.1101/289777 — evolutionary biology — Posted on 2018-03-27

329 A new threat identified in the use of SDHIs pesticides targeting the mitochondrial succinate dehydrogenase enzyme

Benit, P.; Bortoli, S.; Huq, L.; Schiff, M.; Gimenez-Roqueplo, A.-P.; Rak, M.; Gressens, P.; Favier, J.; Rustin, P.

10.1101/289058 — ecology — Posted on 2018-03-27

330 Visualizing multiple inter-organelle contact sites using the organelle-targeted split-GFP system

Kakimoto, Y.; Tashiro, S.; Kojima, R.; Morozumi, Y.; Endo, T.; Tamura, Y.

10.1101/290114 — cell biology — Posted on 2018-03-27

331 Temperature-dependent estimation of Gibbs energies using an updated group contribution method

Du, B.; Zhang, Z.; Gruber, S.; Yurkovich, J.; Palsson, B.; Zielinski, D.

10.1101/289918 — biophysics — Posted on 2018-03-27

332 Network-Based Biomarkers Enable Cross-Disease Biomarker Discovery

Haider, S.; Yao, C.; Sabine, V.; Grzadkowski, M.; Stimper, V.; Starmans, M. H.; Wang, J.; Nguyen, F.; Moon, N. C.; Lin, X.; Drake, C.; Crozier, C. A.; Brookes, C.; van de Velde, C. J.; Hasenburg, A.; Kieback, D.; Markopoulos, C. J.; Dirix, L. Y.; Seynaeve, C.; Rea, D. W.; Kasprzyk, A.; Lio, P.; Lambin, P.; Bartlett, J. M.; Boutros, P. C.

10.1101/289934 — bioinformatics — Posted on 2018-03-27

333 A method for faster purification of serine proteinases from Bothrops alternatus and Bothrops moojeni snake venoms

Gomes Heleno, M. A.; dos Santos, L. D.; Ferreira, R. S.; Barraviera, B.

10.1101/289991 — biochemistry — Posted on 2018-03-27

334 Intronic non-coding RNAs within ribosomal protein coding genes can regulate biogenesis of yeast ribosome

Pande, A.; Sharma, R.; Iyengar, B. R.; Scaria, V.; Pillai, B.; Brahmachari, S. K.

10.1101/289751 — bioinformatics — Posted on 2018-03-27

335 Coupling initial hydrogel microenvironments with mesenchymal stem cell remodeling to define a dynamic hematopoietic stem cell niche

Gilchrist, A. E.; Lee, S.; Hu, Y.; Harley, B.

10.1101/289553 — bioengineering — Posted on 2018-03-27

336 Chronic environmentally relevant levels of Simvastatin induces non-monotonic responses in Zebrafish (Danio rerio)

Barros, S.; Montes, R.; Quintana, J. B.; Rodil, R.; Andre, A.; Capitao, A.; Soares, J.; Santos, M. M.; Neuparth, T.

10.1101/289694 — pharmacology and toxicology — Posted on 2018-03-27

337 Minimally invasive deep-brain imaging through a 50 μm-core multimode fibre.

Vasquez-Lopez, S. A.; Koren, V.; Ploschner, M.; Padamsey, Z.; Cizmar, T.; Emptage, N. J.

10.1101/289793 — neuroscience — Posted on 2018-03-27

338 Cullin1 represses systematic inflammasome activation by binding and catalyzing NLRP3 ubiquitination

Wan, P.; Zhang, Q.; Liu, W.; Jia, Y.; Wang, T.; Wang, W.; Pan, P.; Yang, G.; Xiang, Q.; Huang, S.; Yang, Q.; Zhang, W.; Liu, F.; Wu, K.; Liu, Y.; Wu, J.

10.1101/289637 — immunology — Posted on 2018-03-27

339 Oblique plane single-molecule localization microscopy for thick samples

Kim, J.; Wojcik, M.; Wang, Y.; Xu, K.; Zhang, X.

10.1101/289686 — bioengineering — Posted on 2018-03-27

340 Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor

Xiang, Y.; Halin, J.; Fan, Z.; Hu, S.; Wang, M.; Qiu, L.; Zhang, Z.; Mattjus, P.; Zhang, Y.

10.1101/289785 — biochemistry — Posted on 2018-03-27

341 A re-examination of responding on ratio and regulated-probability interval schedules

Perez, O. D.; Milton, A. L.; Aitken, M. R. F.; Dickinson, A.

10.1101/284216 — animal behavior and cognition — Posted on 2018-03-27

342 Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota

Hoyles, L.; Jimenez-Pranteda, M. L.; Chilloux, J.; Brial, F.; Myridakis, A.; Aranias, T.; Magnan, C.; Gibson, G. R.; Sanderson, J. D.; Nicholson, J. K.; Gauguier, D.; McCartney, A. L.; Dumas, M.-E.

10.1101/225581 — microbiology — Posted on 2018-03-27

343 Identification and characterization of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

O'Shea, E. K.; Yu, Z.; Surface, L. E.; Park, C. Y.; Horlbeck, M. A.; Wyant, G. A.; Abu-Remaileh, M.; Peterson, T. R.; Sabatini, D. M.; Weissman, J. S.

10.1101/289835 — biochemistry — Posted on 2018-03-27

344 Spinal stretch reflexes exploit musculoskeletal redundancy to support postural hand control

Weiler, J.; Gribble, P. L.; Pruszynski, J. A.

10.1101/270116 — neuroscience — Posted on 2018-03-27

345 Long-range inputs and H-current regulate different modes of operation in a multiscale model of mouse M1 microcircuits

Dura-Bernal, S.; Neymotin, S. A.; Suter, B. A.; Shepherd, G. M.; Lytton, W. W.

10.1101/201707 — neuroscience — Posted on 2018-03-27

346 Onset of differentiation is posttranscriptionally controlled in adult neural stem cells

Baser, A.; Dang, Y.; Skabkin, M.; Guelcueler Balta, G.; Kalamakis, G.; Kleber, S.; Goepferich, M.; Schefzik, R.; Santos Lopez, A.; Llorens Bobadilla, E.; Schultz, C.; Fischer, B.; Martin-Villalba, A.

10.1101/289868 — neuroscience — Posted on 2018-03-27

347 Directed functional connectivity using dynamic graphical models

Schwab, S.; Harbord, R.; Zerbi, V.; Elliott, L.; Afyouni, S.; Smith, J. Q.; Woolrich, M. W.; Smith, S. M.; Nichols, T. E.

10.1101/198887 — neuroscience — Posted on 2018-03-27

348 Single cell transcriptome profiling of mouse and hESC-derived pancreatic progenitors

Krentz, N. A.; Lee, M.; Xu, E. E.; Sasaki, S.; Lynn, F. C.

10.1101/289470 — developmental biology — Posted on 2018-03-27

349 Patchiness and scale-free correlations: characterising criticality in ecosystems.

Sankaran, S.; Majumder, S.; Viswanathan, A.; Guttal, V.

10.1101/233429 — ecology — Posted on 2018-03-27

350 Estimating the rate of index hopping on the Illumina HiSeq X platform

van der Valk, T.; Vezzi, F.; Ormestad, M.; Dalen, L.; Guschanski, K.

10.1101/179028 — bioinformatics — Posted on 2018-03-27

351 From de novo to \"de nono\": most novel protein coding genes identified with phylostratigraphy represent old genes or recent duplicates

Casola, C.

10.1101/287193 — genomics — Posted on 2018-03-27

352 Exposing flaws in S-LDSC; reply to Gazal et al.

Speed, D.; Balding, D.

10.1101/280784 — genetics — Posted on 2018-03-27

353 High carnivore population density highlights the conservation value of industrialised sites

Loock, D. J. E.; Williams, S. T.; Emslie, K. W.; Matthews, W. S.; Swanepoel, L. H.

10.1101/260729 — ecology — Posted on 2018-03-27

354 NeoDTI: Neural integration of neighbor information from a heterogeneous network for discovering new drug-target interactions

Wan, F.; Hong, L.; Xiao, A.; Jiang, T.; Zeng, J.

10.1101/261396 — systems biology — Posted on 2018-03-27

355 Cystinosin regulates kidney inflammation through its interaction with galectin-3

Lobry, T.; Miller, R.; Nevo, N.; Rocca, C. J.; Zhang, J.; Catz, S. D.; Moore, F.; Bailleux, A.; Guerrera, I. C.; Gubler, M.-C.; Cheung, W. W.; Mak, R.; Montier, T.; Antignac, C.; Cherqui, S.

10.1101/289702 — molecular biology — Posted on 2018-03-27

356 Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

Molkentine, J. M.; Fujimoto, T. N.; Horvath, T.; Grossberg, A. J.; Deorukhkar, A.; Samuel, E. L. G.; Chan, W. K.; Lorenzi, P. L.; Dantzer, R.; Tour, J. M.; Mason, K. A.; Taniguchi, C.

10.1101/289074 — cancer biology — Posted on 2018-03-27

357 Modelling cell-cell interactions from spatial molecular data with spatial variance component analysis

Arnol, D.; Schapiro, D.; Bodenmiller, B.; Saez-Rodriguez, J.; Stegle, O.

10.1101/265256 — bioinformatics — Posted on 2018-03-27

358 Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses

Palmer, W. H.; Medd, N.; Beard, P. M.; Obbard, D. J.

10.1101/215111 — microbiology — Posted on 2018-03-27

359 Insights into the evolution of extracellular leucine-rich repeats in metazoans with special reference to Toll-like receptor 4

Dhar, D.; Dey, D.; Basu, S.

10.1101/269241 — bioinformatics — Posted on 2018-03-27

360 MoDentify: a tool for phenotype-driven module identification in multilevel metabolomics networks

Do, K. T.; Rasp, D. J. N.- P.; Kastenmueller, G.; Suhre, K.; Krumsiek, J.

10.1101/275057 — systems biology — Posted on 2018-03-27

361 Identification of Animal Behavioral Strategies by Inverse Reinforcement Learning

Yamaguchi, S.; Naoki, H.; Ikeda, M.; Tsukada, Y.; Nakano, S.; Mori, I.; Ishii, S.

10.1101/129007 — neuroscience — Posted on 2018-03-27

362 Attempts to implement CRISPR/Cas9 for genome editing in the oomycete Phytophthora infestans

van den Hoogen, J.; Govers, F.

10.1101/274829 — molecular biology — Posted on 2018-03-27

363 PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28gamma

Jonik-Nowak, B.; Menneteau, T.; Fesquet, D.; Baldin, V.; Bonne-Andrea, C.; Mechali, F.; Fabre, B.; Boisguerin, P.; De Rossi, S.; Henriquet, C.; Pugniere, M.; Ducoux-Petit, M.; Burlet-Schiltz, O.; Lamond, A. I.; Fort, P.; Boulon, S.; Bousquet, M.-P.; Coux, O.

10.1101/160739 — cell biology — Posted on 2018-03-27

364 Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium and stroma

He, J.; Maurer, H. C.; Holmstrom, S. R.; Su, T.; Ahmed, A.; Hibshoosh, H.; Chabot, J. A.; Oberstein, P. E.; Sepulveda, A. R.; Genkinger, J. M.; Zhang, J.; Iuga, A. C.; Bansal, M.; Califano, A.; Olive, K. P.

10.1101/288779 — systems biology — Posted on 2018-03-27

365 Of Rats And Men: Peer Presence And Familiarity Are Key Factors Which Reduce Drug Intake

Giorla, E.; Nordmann, S.; Pelloux, Y.; Roux, P.; Rosellini, S.; Davranche, K.; Montanari, C.; Vilotitch, A.; Huguet, P.; Carrieri, P.; Baunez, C.

10.1101/286518 — neuroscience — Posted on 2018-03-27

366 Deep proteomic analysis of chicken erythropoiesis

Leduc, M.; Gautier, E.-F.; Guillemin, A.; Broussard, C.; Salnot, V.; Lacombe, C.; Gandrillon, O.; Guillonneau, F.; Mayeux, P.

10.1101/289728 — developmental biology — Posted on 2018-03-27

367 Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

Taniguchi, C.; Molkentine, J. M.; Fujimoto, T. N.; Horvath, T.; Grossberg, A. J.; Deorukhkar, A.; Samuel, E. L. G.; Chan, W. K.; Lorenzi, P. L.; Dantzer, R.; Tour, J. M.; Mason, K. A.

10.1101/289074 — cancer biology — Posted on 2018-03-27

368 When to care and when to kill: termites shape their collective response based on stage of infection

Davis, H. E.; Meconcelli, S.; Radek, R.; McMahon, D. P.

10.1101/287441 — animal behavior and cognition — Posted on 2018-03-27

369 Tissue-specific transcriptome for Poeciliopsis prolifica reveals evidence for genetic adaptation related to the evolution of a placental fish.

Jue, N. K.; Foley, R. J.; Reznick, D.; O'Neill, R.; O'Neill, M. J.

10.1101/289488 — genomics — Posted on 2018-03-27

370 Alanine tRNAs translate environment into behavior in Caenorhabditis elegans

Fernandes De Abreu, D. A.; Salinas-Giege, T.; Marechal-Drouard, L.; Remy, J.-J.

10.1101/289629 — evolutionary biology — Posted on 2018-03-27

371 Regulation of DVL2 ubiquitylation by USP9X biases participation in canonical or non-canonical WNT signalling

Nielsen, C. P.; Jernigan, K. K.; MacGurn, J. A.

10.1101/289595 — cell biology — Posted on 2018-03-27

372 Biallelic Mutations in LRRC56 encoding a protein associated with intraflagellar transport, cause mucociliary clearance and laterality defects

Bonnefoy, S.; Watson, C.; Kernohan, K.; Lemos, M.; Hutchinson, S.; Poulter, J.; Crinion, L.; O'Callaghan, C.; Hirst, R.; Rutman, A.; Huang, L.; Hartley, T.; Grynspan, D.; Moya, E.; Li, C.; Carr, I.; Bonthron, D.; Leroux, M.; Care4Rare Canada Consortium, ; Boycott, K.; Bastin, P.; Sheridan, E.

10.1101/288852 — genetics — Posted on 2018-03-27

373 Attempts to implement CRISPR/Cas9 for genome editing in the oomycete Phytophthora infestans

van den Hoogen, J.; Govers, F.

10.1101/274829 — molecular biology — Posted on 2018-03-27

374 Quantification of DNA samples by Ethidium Bromide Spot Technique

Zhao, J.; Zhao, J.; Cummins, A.; Gonzalez, T.; Axler-DiPerte, G.; Camenares, D.

10.1101/289108 — synthetic biology — Posted on 2018-03-27

375 A comprehensive toolkit to enable MinION long-read sequencing in any laboratory

Schalamun, M.; Kainer, D.; Beavan, E.; Nagar, R.; Eccles, D.; Rathjen, J.; Lanfear, R.; Schwessinger, B.

10.1101/289579 — genomics — Posted on 2018-03-27

376 System Biology Modeling with Compositional Microbiome Data Reveals Personalized Gut Microbial Dynamics and Keystone Species

Li, C.; Tucker-Kellogg, L.; Nagarajan, N.

10.1101/288803 — systems biology — Posted on 2018-03-27

377 PRY-1/AXIN signaling regulates lipid metabolism in Caenorhabditis elegans

Ranawade, A.; Mallick, A.; Gupta, B. P.

10.1101/289462 — physiology — Posted on 2018-03-27

378 Modulation of naturalistic maladaptive memories using behavioural and pharmacological reconsolidation-interfering strategies: A systematic review and meta-analysis of clinical and ‘sub-clinical’ studies

Walsh, K. H.; Das, R. K.; Saladin, M. E.; Kamboj, S. K.

10.1101/282293 — neuroscience — Posted on 2018-03-27

379 The ultra-sensitive Nodewalk technique identifies stochastic from virtual, population-based enhancer hubs regulating MYC in 3D: Implications for the fitness of cancer cells

Sumida, N.; Sifakis, E.; Scholz, B. A.; Fernandez Woodbridge, A.; Kiani, N.; Gomez-Cabrero, D.; Svensson, J. P.; Tegner, J.; Gondor, A.; Ohlsson, R.

10.1101/286583 — genomics — Posted on 2018-03-27

380 On the variability of Species Abundance Distributions with trophic guild and community structure

Garcia-Callejas, D.

10.1101/289348 — ecology — Posted on 2018-03-27

381 Neural Data Visualization for Scalable and Generalizable Single Cell Analysis

Cho, H.; Berger, B.; Peng, J.

10.1101/289223 — bioinformatics — Posted on 2018-03-27

382 The formation of intramolecular secondary structure brings mRNA ends in close proximity

Lai, W.-J. C.; Kayedkhordeh, M.; Cornell, E. V.; Farah, E.; Bellaousov, S.; Rietmeijer, R.; Mathews, D. H.; Ermolenko, D. N.

10.1101/289496 — biochemistry — Posted on 2018-03-27

383 Discovery and Characterization of Novel Lignocellulose-Degrading Enzymes from the Porcupine Microbiome

Thornbury, M.; Sicheri, J.; Guinard, C.; Mahoney, D.; Routledge, F.; Curry, M.; Elaghil, M.; Boudreau, N.; Tsai, A.; Slaine, P.; Finlayson-Trick, E.; Getz, L.; Cook, J.; Rohde, J.; McCormick, C.

10.1101/288985 — synthetic biology — Posted on 2018-03-27

384 A thermo-responsive plasmid for biconditional protein expression

Lermant, A.; Magnanon, A.; Silvain, A.; Lubrano, P.; Lhuissier, M. J.; Dury, C.; Follenfant, M.; Guiot, Z.; Christien, G.; Coudert, P.; Arvor, A.; Sportich, M.; Vuillaume, G.; Delettre, N.; Henry, J.; Lafon, E.; Lhernould, T.; Richard, F.; Ismail, A.

10.1101/289264 — synthetic biology — Posted on 2018-03-27

385 Soil salinity inhibits plant shade avoidance

Hayes, S.; Tween, A. L.; van Gelderen, K.; de Vries, M.; Prat, S.; Schuurink, R.; Testerink, C.; Pierik, R.

10.1101/289124 — plant biology — Posted on 2018-03-27

386 Low dose resveratrol promotes hypertrophy in wildtype skeletal muscle and reduces damage in skeletal muscle of exercised mdx mice.

Woodman, K. G.; Coles, C. A.; Toulson, S. L.; Knight, M.; McDonagh, M. M.; Lamande, S. R.; White, J. D.

10.1101/289587 — physiology — Posted on 2018-03-27

387 The perception of color and material in natural tasks

Brainard, D. H.; Cottaris, N. P.; Radonjic, A.

10.1101/288662 — neuroscience — Posted on 2018-03-27

388 A study of phenotypic plasticity of Saccharomyces cerevisiae in natural grape juices shed light on allelic variation under balanced selection.

Peltier, E.; Sharma, V.; Marti Raga, M.; Roncoroni, M.; Bernard, M.; Jiranek, V.; Gibon, Y.; Marullo, P.

10.1101/288944 — genetics — Posted on 2018-03-27

389 Porter 5: state-of-the-art ab initio prediction of protein secondary structure in 3 and 8 classes

Torrisi, M.; Kaleel, M.; Pollastri, G.

10.1101/289033 — bioinformatics — Posted on 2018-03-27

390 Bradyrhizobium diazoefficiens USDA 110-Glycine max interactome provides candidate proteins associated with symbiosis

Zhang, L.; Liu, J.-Y.; Gu, H.; Du, Y.; Zuo, J.-F.; Zhang, Z.; Zhang, M.; Li, P.; Dunwell, J. M.; Cao, Y.; Zhang, Z.; Zhang, Y.-M.

10.1101/288811 — bioinformatics — Posted on 2018-03-27

391 Ancient DNA reveals the chronology of walrus ivory trade from Norse Greenland

Star, B.; Barrett, J. H.; Gondek, A. T.; Boessenkool, S.

10.1101/289165 — genomics — Posted on 2018-03-27

392 Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

Oberhofer, G.; Ivy, T.; Hay, B. A.

10.1101/289546 — genetics — Posted on 2018-03-27

393 Loss of CREST leads to neuroinflammatory responses and ALS-like motor defects in mice

Cheng, C.; Yang, K.; Wu, X.; Zhang, Y.; Shan, S.; Gitler, A.; Ghosh, A.; Qiu, Z.

10.1101/260133 — neuroscience — Posted on 2018-03-27

394 Small non-coding RNA expression in developing mouse nephron progenitor cells

Phua, Y. L.; Clugston, A.; Chen, K. H.; Kostka, D.; Ho, J.

10.1101/289421 — developmental biology — Posted on 2018-03-27

395 Label-free prediction of three-dimensional fluorescence images from transmitted light microscopy

Ounkomol, C.; Seshamani, S.; Maleckar, M. M.; Collman, F.; Johnson, G.

10.1101/289504 — cell biology — Posted on 2018-03-27

396 The Role of Cytoplasmic Interactions in the Collective Polarization of Tissues and its Interplay with Cellular Geometry

Shadkhoo, S.; Mani, M.

10.1101/289520 — biophysics — Posted on 2018-03-27

397 Evolution of the D. melanogaster chromatin landscape and its associated proteins

Parey, E.; Crombach, A.

10.1101/284828 — evolutionary biology — Posted on 2018-03-26

398 Data-driven approaches for Tau-PET imaging biomarkers in Alzheimer’s disease

Vogel, J. W.; Mattsson, N.; Iturria-Medina, Y.; Strandberg, T. O.; Scholl, M.; Dansereau, C.; Villeneuve, S.; van der Flier, W. M.; Scheltens, P.; Bellec, P.; Evans, A. C.; Hansson, O.; Ossenkoppele, R.; the Alzheimer's Disease Neuroimaging Initiative, ; the Swedish BioFINDER study,

10.1101/244574 — neuroscience — Posted on 2018-03-26

399 Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

Taniguchi, C.; Molkentine, J. M.; Fujimoto, T. N.; Horvath, T.; Grossberg, A. J.; Deorukhkar, A.; Samuel, E. L. G.; Chan, W. K.; Lorenzi, P. L.; Dantzer, R.; Tour, J. M.; Mason, K. A.

10.1101/289074 — cancer biology — Posted on 2018-03-26

400 Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo

Biscans, A.; Coles, A.; Haraszti, R.; Echeverria, D.; Hassler, M.; Osborn, M.; Khvorova, A.

10.1101/289439 — biochemistry — Posted on 2018-03-26

401 An attenuated CRISPR-Cas system in Enterococcus faecalis permits DNA acquisition

Hullahalli, K.; Rodrigues, M.; Nguyen, U.; Palmer, K.

10.1101/232322 — microbiology — Posted on 2018-03-26

402 Transposable elements are important contributors to standing variation in gene expression in Capsella grandiflora

Uzunovic, J.; Josephs, E. B.; Stinchcombe, J. R.; Wright, S. I.

10.1101/289173 — evolutionary biology — Posted on 2018-03-26

403 Development of a Cx46 targeting strategy for cancer stem cells

Mulkearns-Hubert, E. E.; Torre-Healy, L. A.; Silver, D. J.; Eurich, J. T.; Serbinowski, E.; Hitomi, M.; Zhou, J.; Przychodzen, B.; Zhang, R.; Sprowls, S. A.; Hale, J. S.; Alban, T.; Berezovsky, A.; Bell, B. A.; Lockman, P. R.; Jha, B. K.; Lathia, J. D.

10.1101/289397 — cancer biology — Posted on 2018-03-26

404 Pseudomonas syringae evades phagocytosis in animal cells through type III effector-mediated inhibition of the LIM kinase-cofilin system

Ryu, C.-M.; Yoon, S.-J.; Lee, S.; Kim, J.-S.; Lee, S.-H.; Choi, S.; Min, J.-K.; Choi, I.; Park, Y.-J.

10.1101/287508 — microbiology — Posted on 2018-03-26

405 Large-scale neuroimaging and genetic study reveals genetic architecture of brain white matter microstructure

Zhao, B.; Zhang, J.; Ibrahim, J.; Santelli, R.; Li, Y.; Li, T.; Shan, Y.; Zhu, Z.; Zhou, F.; Liao, H.; Nichols, T.; Zhu, H.

10.1101/288555 — genetics — Posted on 2018-03-26

406 Estimating the proportion of bystander selection for antibiotic resistance in the US

Tedijanto, C.; Olesen, S.; Grad, Y.; Lipsitch, M.

10.1101/288704 — epidemiology — Posted on 2018-03-26

407 Cell-lineage specificity of primary cilia during epididymis post-natal development

Bernet, A.; Bastien, A.; Soulet, D.; Jerczynski, O.; Roy, C.; Bianchi Rodrigues Alves, M.; Lecours, C.; Tremblay, M.-E.; Bailey, J.; Robert, C.; Belleannee, C.

10.1101/288977 — developmental biology — Posted on 2018-03-26

408 Directed, but not random, breast cancer cell migration is faster in the G1 phase of the cell cycle in 2D and 3D environments

Pourfarhangi, K. E.; Cardenas de la Hoz, E.; Cohen, A. R.; Gligorijevic, B.

10.1101/288183 — cancer biology — Posted on 2018-03-26

409 Dynamic and Structural Modeling of the Specificity in Protein-DNA Interactions Guided by Binding Assay and Structure Data

Tan, C.; Takada, S.

10.1101/288795 — biophysics — Posted on 2018-03-26

410 Inexpensive, scalable camera system for tracking rats in large spaces

Saxena, R.; Barde, W.; Deshmukh, S. S.

10.1101/285460 — neuroscience — Posted on 2018-03-26

411 Of Rats And Men: Peer Presence And Familiarity Are Key Factors Which Modulate Drug Intake

Giorla, E.; Nordmann, S.; Pelloux, Y.; Roux, P.; Rosellini, S.; Davranche, K.; Vilotitch, A.; Huguet, P.; Carrieri, P.; Baunez, C.

10.1101/286518 — neuroscience — Posted on 2018-03-26

412 Conformational dynamics of a photosynthetic light-harvesting complex in native thylakoid membranes

Azadi-Chegeni, F.; Ward, M. E.; Perin, G.; Simionato, D.; Morosinotto, T.; Baldus, M.; Pandit, A.

10.1101/288860 — biophysics — Posted on 2018-03-26

413 Naked mole-rat brain neurons are resistant to acid-induced cell death

Husson, Z.; Smith, E. S. J.

10.1101/260901 — neuroscience — Posted on 2018-03-26

414 How the Central American Seaway and an ancient northern passage affected flatfish diversification

Byrne, L.; Chapleau, F.; Aris-Brosou, S.

10.1101/247304 — evolutionary biology — Posted on 2018-03-26

415 Decomposing parasite fitness in a two-host, two-parasite system reveals the underpinnings of parasite specialization

Lievens, E. J. P.; Perreau, J. M. A.; Agnew, P.; Michalakis, Y.; Lenormand, T.

10.1101/256974 — evolutionary biology — Posted on 2018-03-26

416 SPADIS: An Algorithm for Selecting Predictive and Diverse SNPs in GWAS

Yilmaz, S.; Tastan, O.; Cicek, A. E.

10.1101/256677 — bioinformatics — Posted on 2018-03-26

417 Human Herpes Virus 6 (HHV-6) - Pathogen or Passenger? A pilot study of clinical laboratory data and next generation sequencing

Sharp, C.; Golubchik, T.; Gregory, W. F.; McNaughton, A.; Gow, N.; Selvaratnam, M.; Mirea, A.; Foster, D.; Andersson, M.; Klenerman, P.; Jeffery, K.; Matthews, P.

10.1101/236083 — microbiology — Posted on 2018-03-26

418 A hypermorphic Nfkbid allele represents an Idd7 locus gene contributing to impaired thymic deletion of autoreactive diabetogenic CD8+ T-cells in NOD mice.

Presa, M.; Racine, J. J.; Dwyer, J. R.; Lamont, D.; Ratiu, J. J.; Sarsani, V. K.; Chen, Y.-G.; Geurts, A.; Schmitz, I.; Stearns, T.; Allocco, J.; Chapman, H. D.; Serreze, D. V.

10.1101/249094 — immunology — Posted on 2018-03-26

419 Urbanization-driven changes in web-building are decoupled from body size in an orb-web spider

Dahirel, M.; De Cock, M.; Vantieghem, P.; Bonte, D.

10.1101/214924 — ecology — Posted on 2018-03-26

420 FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining

Bachman, J. A.; Gyori, B. M.; Sorger, P.

10.1101/225698 — bioinformatics — Posted on 2018-03-26

421 Neuronal integration in the adult olfactory bulb is a non-selective addition process

Platel, J.-C.; Angelova, A.; Bugeon, S.; Ganay, T.; Chudotvorova, I.; Deloulme, J.-C.; Beclin, C.; Tiveron, M.-C.; Core, N.; Cremer, H.

10.1101/289009 — neuroscience — Posted on 2018-03-26

422 A Polymorphic Residue That Attenuates the Antiviral Potential of Interferon Lambda 4 in Hominid Lineages

Bamford, C. G. G.; Aranday-Cortes, E.; Cordeiro Filipe, I.; Sukumar, S.; Mair, D.; da Silva Filipe, A.; Mendoza, J. L.; Garcia, K. C.; Fan, S.; Tishkoff, S. A.; McLauchlan, J.

10.1101/214825 — immunology — Posted on 2018-03-26

423 Clustering de Novo by Gene of Long Reads from Transcriptomics Data

Marchet, C.; Lecompte, L.; Da Silva, C.; Cruaud, C.; Aury, J. M.; Nicolas, J.; Peterlongo, P.

10.1101/170035 — bioinformatics — Posted on 2018-03-26

424 An Observational Study of Ballooning in Large Spiders: Nanoscale Multi-Fibers Enable Large Spiders’ Soaring Flight

Cho, M.; Neubauer, P.; Fahrenson, C.; Rechenberg, I.

10.1101/206334 — zoology — Posted on 2018-03-26

425 A note on the analysis of two-stage task results: how changes in task structure affect what model-free and model-based strategies predict about the effects of reward and transition on the stay probability

Feher da Silva, C.; Hare, T. A.

10.1101/187856 — neuroscience — Posted on 2018-03-26

426 Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron

Galliano, E.; Franzoni, E.; Breton, M.; Chand, A. N.; Byrne, D. J.; Murthy, V. N.; Grubb, M. S.

10.1101/196006 — neuroscience — Posted on 2018-03-26

427 Large-Scale Structure and Individual Fingerprints of Locally Coupled Sleep Oscillations

Cox, R.; Mylonas, D. S.; Manoach, D. S.; Stickgold, R.

10.1101/289157 — neuroscience — Posted on 2018-03-26

428 An information-theoretic perspective on the costs of cognition

Zenon, A.; Solopchuk, O.; Pezzulo, G.

10.1101/208280 — neuroscience — Posted on 2018-03-26

429 Precision weighting of cortical unsigned prediction errors is mediated by dopamine and benefits learning

Haarsma, J.; Fletcher, P. C.; Ziauddeen, H.; Spencer, T. J.; Diederen, K. M. J.; Murray, G. K.

10.1101/288936 — neuroscience — Posted on 2018-03-26

430 Semiology, clustering, periodicity and natural history of seizures in an experimental visual cortical epilepsy model

Chang, B.-L.; Leite, M.; Snowball, A.; Chabrol, E.; Leib, A.; Walker, M. C.; Kullmann, D. M.; Schorge, S.; Wykes, R. C.

10.1101/289256 — neuroscience — Posted on 2018-03-26

431 The conflict negativity: A neural correlate of value conflict and indecision during financial decision making

Petersen, G.-K.; Saunders, B.; Inzlicht, M.

10.1101/174136 — neuroscience — Posted on 2018-03-26

432 NeatSeq-Flow: A Lightweight High Throughput Sequencing Workflow Platform for Non-Programmers and Programmers alike

Sklarz, M. Y.; Levin, L.; Gordon, M.; Chalifa-Caspi, V.

10.1101/173005 — bioinformatics — Posted on 2018-03-26

433 Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium and stroma

10.1101/288779 — systems biology — Posted on 2018-03-26

434 Genetic landscapes reveal how human genetic diversity aligns with geography

Peter, B. M.; Petkova, D.; Novembre, J.

10.1101/233486 — evolutionary biology — Posted on 2018-03-26

435 Cyclophilins A and B Oppositely Regulate Renal Tubular Epithelial Phenotype

Sarro, E.; Duran, M.; Rico, A.; Croatt, A. J.; Nath, K. A.; Salcedo, M. T.; Gundelach, J. H.; Batlle, D.; Bram, R. J.; Meseguer, A.

10.1101/288886 — molecular biology — Posted on 2018-03-26

436 PIP5k1 β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation

Zhao, X.-y.; Hu, G.; Wang, C.; Jiang, L.; Zhao, J.; Xu, J.; Zhang, X.

10.1101/288910 — cell biology — Posted on 2018-03-26

437 UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport

Reddy Sure, G.; Chatterjee, A.; Mishra, N.; Sabharwal, V.; Devireddy, S.; Awathi, A.; Mohan, S.; Koushika, S. P.

10.1101/279372 — genetics — Posted on 2018-03-26

438 Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly

Yamaguchi, H.; Oda, T.; Kikkawa, M.; Takeda, H.

10.1101/288837 — cell biology — Posted on 2018-03-26

439 Strong replicators associated with open chromatin are sufficient to establish an early replicating domain

Brossas, C.; Chilaka, S.; Counillon, A.; Laurent, M.; Goncalves, C.; Duriez, B.; Prioleau, M.-N.

10.1101/289025 — molecular biology — Posted on 2018-03-26

440 A mutation-led search for novel functional domains in MeCP2

Guy, J.; Alexander-Howden, B.; FitzPatrick, L.; DeSousa, D.; Koerner, M.; Selfridge, J.; Bird, A. P.

10.1101/288878 — molecular biology — Posted on 2018-03-26

441 Cumulative regulatory potential of clustered methyl-arginine protein modifications

Woodsmith, J.; Casado-Medrano, V.; Benlasfer, N.; Eccles, R.; Hutten, S.; Heine, C.; Thormann, V.; Abou-Ajram, C.; Rocks, O.; Dormann, D.; Stelzl, U.

10.1101/289041 — cell biology — Posted on 2018-03-26

442 DEsingle for detecting three types of differential expression in single-cell RNA-seq data

Miao, Z.; Deng, K.; Wang, X.; Zhang, X.

10.1101/173997 — bioinformatics — Posted on 2018-03-26

443 Evidence of non-tandemly repeated rDNAs and their intragenomic heterogeneity in Rhizophagus irregularis

Maeda, T.; Kobayashi, Y.; Kameoka, H.; Okuma, N.; Takeda, N.; Yamaguchi, K.; Bino, T.; Shigenobu, S.; Kawaguchi, M.

10.1101/205864 — plant biology — Posted on 2018-03-26

444 Divergent effects of healthy ageing on semantic knowledge and control: Evidence from novel comparisons with semantically-impaired patients

Hoffman, P.

10.1101/216192 — neuroscience — Posted on 2018-03-26

445 Clustering huge protein sequence sets in linear time

Steinegger, M.; Soding, J.

10.1101/104034 — bioinformatics — Posted on 2018-03-26

446 Cortical circuit-based lossless neural integrator for perceptual decision-making

Lee, J. H.; Tsunada, J.; Vijayan, S.; Cohen, Y. E.

10.1101/158865 — neuroscience — Posted on 2018-03-26

447 A Deep Predictive Coding Network for Learning Latent Representations

Dora, S.; Pennartz, C. M. A.; Bohte, S. M.

10.1101/278218 — neuroscience — Posted on 2018-03-26

448 Corrigendum and follow-up: Whole genome sequencing of multiple CRISPR-edited mouse lines suggests no excess mutations.

Schaefer, K. A.; Darbro, B. W.; Colgan, D. F.; Tsang, S. H.; Bassuk, A. G.; Mahajan, V. B.

10.1101/154450 — bioengineering — Posted on 2018-03-26

449 Model-based fMRI reveals dissimilarity processes underlying base-rate neglect

O'Bryan, S. R.; Worthy, D. A.; Livesey, E. J.; Davis, T.

10.1101/130716 — neuroscience — Posted on 2018-03-26

450 Network structure of the human musculoskeletal system shapes neural interactions on multiple timescales

Kerkman, J. N.; Daffertshofer, A.; Gollo, L.; Breakspear, M.; Boonstra, T. W.

10.1101/181818 — neuroscience — Posted on 2018-03-26

451 Characterisation of gut microbiota of farmed Chinook salmon using metabarcoding

Ciric, M.; Waite, D.; Draper, J.; Jones, J. B.

10.1101/288761 — microbiology — Posted on 2018-03-26

452 Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium and stroma

He, J.; Maurer, H. C.; Holmstrom, S. R.; Su, T.; Ahmed, A.; Hibshoosh, H.; Chabot, J. A.; Oberstein, P. E.; Sepulveda, A. R.; Genkinger, J. M.; Zhang, J.; Iuga, A. C.; Califano, A.; Bansal, M.; Olive, K. P.

10.1101/288779 — systems biology — Posted on 2018-03-26

453 Combinatorial neural inhibition for stimulus selection across space

Mahajan, N. R.; Mysore, S. P.

10.1101/243279 — neuroscience — Posted on 2018-03-26

454 Microstructural properties of the vertical occipital fasciculus explain the variability in human stereoacuity

Oishi, H.; Takemura, H.; Aoki, S. C.; Fujita, I.; Amano, K.

10.1101/288753 — neuroscience — Posted on 2018-03-26

455 Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisation

Noyce, A. J.; Kia, D.; Heilbron, K.; Jepson, J.; Hemani, G.; International Parkinson's Disease Genomics Consortium, ; The 23andMe Research Team, ; Hinds, D.; Lawlor, D. A.; Davey Smith, G.; Hardy, J.; Singleton, A.; Nalls, M.; Wood, N.

10.1101/288241 — epidemiology — Posted on 2018-03-26

456 Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

Tynkkynen, T.; Wang, Q.; Ekholm, J.; Anufrieva, O.; Ohukainen, P.; Vepsalainen, J.; Mannikko, M.; Keinanen-Kiukaanniemi, S.; Holmes, M. V.; Goodwin, M.; Ring, S.; Chambers, J. C.; Kooner, J.; Jarvelin, M.-R.; Kettunen, J.; Hill, M.; Davey Smith, G.; Ala-Korpela, M.

10.1101/288993 — epidemiology — Posted on 2018-03-26

457 Appraising the causal relevance of DNA methylation for risk of lung cancer

Battram, T.; Richmond, R.; Baglietto, L.; Haycock, P.; Perduca, V.; Bojesen, S.; Gaunt, T.; Hemani, G.; Guida, F.; Carreras Torres, R.; Hung, R.; Amos, C.; Freeman, J.; Sandanger, T.; Nost, T. H.; Nordestgaard, B.; Teschendorff, A.; Polidoro, S.; Vineis, P.; Severi, G.; Hodge, A.; Giles, G.; Grankvist, K.; Johansson, M.; Johansson, M.; Davey Smith, G.; Relton, C.

10.1101/287888 — epidemiology — Posted on 2018-03-26

458 RaftProt V2: understanding membrane microdomain function through lipid raft proteomes

Mohamed, A.; Shah, A.; Chen, D.; Hill, M. M.

10.1101/286039 — bioinformatics — Posted on 2018-03-26

459 Linear-double-stranded DNA (ldsDNA) based AND logic computation in mammalian cells

Su, W.; Zhang, C.; Li, S.

10.1101/266056 — synthetic biology — Posted on 2018-03-26

460 Deep Learning Based BCI Control of a Robotic Service Assistant Using Intelligent Goal Formulation

Kuhner, D.; Fiederer, L. D. J.; Aldinger, J.; Burget, F.; Völker, M.; Schirrmeister, R. T.; Do, C.; Boedecker, J.; Nebel, B.; Ball, T.; Burgard, W.

10.1101/282848 — neuroscience — Posted on 2018-03-26

461 High-accuracy Decoding of Complex Visual Scenes from Neuronal Calcium Responses

Ellis, R. J.; Michaelides, M.

10.1101/271296 — neuroscience — Posted on 2018-03-26

462 Efficacy and acceptability of non-invasive brain stimulation for the treatment of adult unipolar and bipolar depression: A systematic review and meta-analysis of randomised sham-controlled trials

Mutz, J.; Edgcumbe, D. R.; Brunoni, A. R.; Fu, C. H. Y.

10.1101/287656 — neuroscience — Posted on 2018-03-26

463 From de novo to \"de nono\": most novel protein coding genes identified with phylostratigraphy represent old genes or recent duplicates

Casola, C.

10.1101/287193 — genomics — Posted on 2018-03-26

464 The median and the mode as robust meta-analysis methods in the presence of small study effects

Hartwig, F. P.; Davey Smith, G.; Schmidt, A. F.; Bowden, J.

10.1101/288050 — epidemiology — Posted on 2018-03-26

465 Causal mechanisms of a healthy lifestyle intervention for patients with musculoskeletal pain who are overweight or obese

Williams, A.; Lee, H.; Kamper, S. J.; O'Brien, K.; Wiggers, J.; Wolfenden, L.; Yoong, S. L.; Hodder, R. K.; Robson, E. K.; Haskins, R.; McAuley, J. H.; Williams, C. M.

10.1101/286757 — clinical trials — Posted on 2018-03-26

466 Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome

Mylonas, R.; Beer, I.; Iseli, C.; Chong, C.; Pak, H.; Gfeller, D.; Coukos, G.; Xenarios, I.; Mueller, M.; Bassani-Sternberg, M.

10.1101/288209 — bioinformatics — Posted on 2018-03-26

467 Temporal epigenomic profiling identifies AHR and GLIS1 as super-enhancer controlled regulators of mesenchymal multipotency

Gerard, D.; Schmidt, F.; Ginolhac, A.; Schmitz, M.; Halder, R.; Ebert, P.; Schulz, M. H.; Sauter, T.; Sinkkonen, L.

10.1101/183988 — genomics — Posted on 2018-03-26

468 Sample size calculation for estimating key epidemiological parameters using serological data and mathematical modelling

Blaizot, S.; Herzog, S. A.; Abrams, S.; Theeten, H.; Litzroth, A.; Hens, N.

10.1101/287581 — epidemiology — Posted on 2018-03-26

469 Estimating the proportion of bystander selection for antibiotic resistance in the US

Tedijanto, C.; Olesen, S.; Grad, Y.; Lipsitch, M.

10.1101/288704 — epidemiology — Posted on 2018-03-26

470 Body mass index and mortality in UK Biobank: revised estimates using Mendelian randomization

Wade, K. H.; Carslake, D.; Sattar, N.; Davey Smith, G.; Timpson, N. J.

10.1101/281436 — epidemiology — Posted on 2018-03-26

471 Mapping malaria by combining parasite genomic and epidemiologic data

Wesolowski, A.; Taylor, A.; Chang, H.-H.; Verity, R.; Tessema, S.; Bailey, J.; Perkins, T. A.; Neafsey, D.; Greenhouse, B.; Buckee, C. O.

10.1101/288506 — epidemiology — Posted on 2018-03-26

472 Structural insights into the conformational plasticity of the full-length trimeric HIV-1 envelope glycoprotein precursor

Zhang, S.; Wang, W. L.; Chen, S.; Lu, M.; Go, E. P.; Steinbock, R. T.; Ding, H.; Desaire, H.; Kappes, J. C.; Sodroski, J. G.; Mao, Y.

10.1101/288472 — microbiology — Posted on 2018-03-25

473 Taxonomy annotation errors in 16S rRNA and fungal ITS sequence databases

Edgar, R. C.

10.1101/288654 — microbiology — Posted on 2018-03-25

474 A Global Analysis of Mutations Accompanying Microevolution in the Heterozygous Diploid Pathogen Candida albicans

Ene, I. V.; Farrer, R. A.; Hirakawa, M. P.; Agwamba, K.; Cuomo, C. A.; Bennett, R. J.

10.1101/288597 — genomics — Posted on 2018-03-25

475 Natural variation in couch potato mediates rapid evolution of learning and reproduction in natural populations of Drosophila melanogaster

Behrman, E. L.; Kawecki, T. J.; Schmidt, P.

10.1101/288696 — evolutionary biology — Posted on 2018-03-25

476 Share, but unequally: A mechanism for emergence and maintenance of intratumor heterogeneity

Li, X.; Thirumalai, D.

10.1101/288670 — cancer biology — Posted on 2018-03-25

477 Deciphering signaling specificity with interpretable deep neural networks

Luo, Y.; Ma, J.; Liu, Y.; Ye, Q.; Ideker, T.; Peng, J.

10.1101/288647 — bioinformatics — Posted on 2018-03-25

478 Low-Cost Touchscreen Driven Programmable Dual Syringe Pump for Life Science Applications

Garcia, V. E.; Liu, J.; DeRisi, J.

10.1101/288290 — bioengineering — Posted on 2018-03-25

479 Modeling semantic encoding in a common neural representational space

Van Uden, C. E.; Nastase, S. A.; Connolly, A. C.; Feilong, M.; Hansen, I.; Gobbini, M. I.; Haxby, J. V.

10.1101/288605 — neuroscience — Posted on 2018-03-25

480 A Generative Growth Model for Thalamocortical Axonal Branching in Primary Visual Cortex

Kassraian Fard, P.; Pfeiffer, M.; Bauer, R.

10.1101/288522 — neuroscience — Posted on 2018-03-25

481 Thalamocortical and intracortical inputs differentiate layer-specific mouse auditory corticocollicular neurons

Slater, B. J.; Sons, S. K.; Llano, D. A.

10.1101/288431 — neuroscience — Posted on 2018-03-25

482 Large-scale neuroimaging and genetic study reveals genetic architecture of brain white matter microstructure

Zhao, B.; Zhang, J.; Ibrahim, J.; Santelli, R.; Li, Y.; Li, T.; Shan, Y.; Zhu, Z.; Zhou, F.; Liao, H.; Nichols, T.; Thompson, P.; Zhu, H.

10.1101/288555 — genetics — Posted on 2018-03-25

483 Evolutionary rate coevolution between mitochondria and mitochondria-associated nuclear-encoded proteins in insects

Yan, Z.; Ye, G.-y.; Werren, J.

10.1101/288456 — evolutionary biology — Posted on 2018-03-25

484 Competing endogenous RNA network: Potential entrants to gene editing in Hepatocellular Carcinoma

Shafei, A.; Matboli, M.; Ali, M.; Nagy, Z.; Reda, M.; Salah, M.; Hamdy, A.; Abdelgawad, M.; Ashry, A.; Tarek, M.; Saber, O.; Azazy, A.; Mohamed, B.; Hassan, M.; El-Khazragy, N.; El-Khamisy, S.

10.1101/288381 — bioengineering — Posted on 2018-03-25

485 Benfotiamine reduces pathology and improves muscle function in mdx mice.

Woodman, K. G.; Coles, C. A.; Toulson, S. L.; Gibbs, E. M.; Knight, M.; McDonagh, M.; Crosbie-Watson, R. H.; Lamande, S. R.; White, J. D.

10.1101/288621 — physiology — Posted on 2018-03-25

486 Expansion, retention and loss in the Acyl-CoA Synthetase \"Bubblegum\" (Acsbg) gene family in vertebrate history

Lopes-Marques, M.; Machado, A. M.; Ruivo, R.; Fonseca, E.; Carvalho, E.; Castro, L. F.

10.1101/288530 — genetics — Posted on 2018-03-25

487 Network Architecture and Mutational Sensitivity of the C. elegans Metabolome

Johnson, L. M.; Chandler, L. M.; Davies, S. K.; Baer, C. F.

10.1101/181511 — systems biology — Posted on 2018-03-25

488 Positional information encoded in the dynamic differences between neighbouring oscillators during vertebrate segmentation.

Boareto, M.; Tomka, T.; Iber, D.

10.1101/286328 — developmental biology — Posted on 2018-03-25

489 High affinity Na+ transport by wheat HKT1;5 is blocked by K+

Xu, B.; Hrmova, M.; Gilliham, M.

10.1101/280453 — plant biology — Posted on 2018-03-25

490 Checkpoint signaling abrogation after cell cycle reentry reveals that differentiated neurons are mitotic cells

Walton, C. C.; Zhang, W.; Patino-Parrado, I.; Barrio-Alonso, E.; Garrido, J.-J.; Frade, J. M.

10.1101/288589 — neuroscience — Posted on 2018-03-25

491 Transcriptional and electrophysiological aberrations in an induced pluripotent stem cell-derived model of spinocerebellar ataxia type 7

Watson, L. M.; Smith, D. C.; Raimondo, J. V.; Burman, R. J.; Ballo, R.; Scholefield, J.; Tyers, L.; Cowley, S. A.; Wood, M. J.; Kidson, S. H.; Greenberg, L. J.

10.1101/288480 — neuroscience — Posted on 2018-03-25

492 COSSMO: Predicting Competitive Alternative Splice Site Selection using Deep Learning

Bretschneider, H.; Gandhi, S.; Zuberi, K.; Deshwar, A. G.; Frey, B. J.

10.1101/255257 — bioinformatics — Posted on 2018-03-25

493 Organization of Neural Population Code in Mouse Visual System

Esfahany, K.; Siergiej, I.; Zhao, Y.; Park, I. M.

10.1101/220558 — neuroscience — Posted on 2018-03-25

494 Spatial Control of Draper Receptor Signaling Initiates Apoptotic Cell Engulfment

Williamson, A. P.; Vale, R. D.

10.1101/198986 — cell biology — Posted on 2018-03-25

495 incR: a new R package to analyse incubation behaviour

Capilla-Lasheras, P.

10.1101/232520 — animal behavior and cognition — Posted on 2018-03-25

496 Using Temporal ICA to Selectively Remove Global Noise While Preserving Global Signal in Functional MRI Data

Glasser, M. F.; Coalson, T. S.; Bijsterbosch, J. D.; Harrison, S. J.; Harms, M. P.; Anticevic, A.; Van Essen, D. C.; Smith, S. M.

10.1101/193862 — neuroscience — Posted on 2018-03-25

497 A Connectome Wide Functional Signature of Transdiagnostic Risk for Mental Illness

Elliott, M. L.; Romer, A. L.; Knodt, A. R.; Hariri, A. R.

10.1101/196220 — neuroscience — Posted on 2018-03-25

498 Deep transfer learning-based hologram classification for molecular diagnostics

Kim, S.-J.; Wang, C.; Zhao, B.; Im, H.; Min, J.; Choi, N. R.; Castro, C. M.; Weissleder, R.; Lee, H.; Lee, K.

10.1101/192559 — bioengineering — Posted on 2018-03-25

499 Using Arterial Spin Labelling to Investigate Spontaneous and Evoked Ongoing Musculoskeletal Pain

Wartolowska, K. A.; Bulte, D. P.; Chappell, M. A.; Jenkinson, M.; Okell, T. W.; Webster, M.; Carr, A. J.

10.1101/163196 — neuroscience — Posted on 2018-03-25

500 Orb-web spider color polymorphism through the eyes of multiple prey and predators

Ximenes, N.; Gawryszewski, F. M.

10.1101/160341 — animal behavior and cognition — Posted on 2018-03-25

501 Scope for sympatric giant-dwarf speciation driven by cannibalism in South-American annual killifish (Austrolebias)

Van Dooren, T.; Thomassen, H. A.; Smit, F.; Helmstetter, A. J.; Savolainen, V.

10.1101/121806 — evolutionary biology — Posted on 2018-03-25

502 Performance Metrics for an Application-driven Selection and Optimization of Psychophysical Sampling Procedures

Rinderknecht, M. D.; Lambercy, O.; Gassert, R.

10.1101/287904 — neuroscience — Posted on 2018-03-25

503 N-hydroxy-pipecolic acid is a mobile signal that induces systemic disease resistance in Arabidopsis

Chen, Y. C.; Holmes, E.; Rajniak, J.; Kim, J.-G.; Tang, S.; Fischer, C.; Mudgett, M. B.; Sattely, E.

10.1101/288449 — plant biology — Posted on 2018-03-25

504 PP-2, a src-kinase inhibitor, is a potential corrector for F508del-CFTR in cystic fibrosis

Wang, Y.; Arora, K.; Yang, F.; Shin, W.-H.; Chen, J.; Kihara, D.; Naren, A. P.; Jegga, A. G.

10.1101/288324 — systems biology — Posted on 2018-03-24

505 Spatially clustered loci with multiple enhancers are frequent targets of HIV-1

Lucic, B.; Chen, H.-C.; Kuzman, M.; Zorita, E.; Wegner, J.; Minnerker, V.; Roukos, V.; Benkirane, M.; Weng, W.; Schmidt, M.; Fronza, R.; Stadhouders, R.; Vlahovicek, K.; J Filion, G.; Lusic, M.

10.1101/287896 — genomics — Posted on 2018-03-24

506 Inhibition of mitochondrial ferredoxin 1 (FDX1) prevents adaptation to proteotoxic stress

Tsvetkov, P.; Detappe, A.; Cai, K.; Keys, H. R.; Brune, Z.; Ying, W.; Thiru, P.; Reidy, M.; Kugener, G.; Tsherniak, A.; Santagata, S.; Whitesell, L.; Markley, J. L.; Ghobrial, I. M.; Lindquist, S.

10.1101/288365 — cancer biology — Posted on 2018-03-24

507 csuWGCNA: a combination of signed and unsigned WGCNA to capture negative correlations

Dai, R.; Xia, Y.; Liu, C.; Chen, C.

10.1101/288225 — bioinformatics — Posted on 2018-03-24

508 Genome-wide survey and expression analysis of the SLAC/SLAH gene family in pear (Pyrus bretschneideri) and other members of the Rosaceae

Wu, J.; Chen, G.; Li, X.; Qiao, X.; Li, J.; Kou, X.; Wang, L.; Wu, X.; Wang, G.; Yin, H.; Wang, P.; Zhang, S.-L.

10.1101/288308 — bioinformatics — Posted on 2018-03-24

509 A Machine Learning Approach Predicts Tissue-Specific Drug Adverse Events

Madhukar, N. S.; Gayvert, K.; Gilvary, C.; Elemento, O.

10.1101/288332 — pharmacology and toxicology — Posted on 2018-03-24

510 No Evidence for Communication in the Complete Locked-in State

Spueler, M.

10.1101/287631 — neuroscience — Posted on 2018-03-24

511 The rhesus monkey hippocampus critically contributes to scene memory retrieval, but not new learning

Froudist Walsh, S.; Browning, P. G. F.; Croxson, P. L.; Murphy, K. L.; Shamy, J. L.; Veuthey, T. L.; Wilson, C. R. E.; Baxter, M. G.

10.1101/288407 — neuroscience — Posted on 2018-03-24

512 Y chromosomal noncoding RNA regulates autosomal gene expression via piRNAs in mouse testis

Reddy, H. M.; Bhattacharya, R.; Jehan, Z.; Mishra, K.; Annapurna, P.; Tiwari, S.; Praveena, N. M.; Alex, J. L.; Dhople, V. M.; Singh, L.; Sivaramakrishnan, M.; Chaturvedi, A.; Rangaraj, N.; Thomas, S. M.; Sridevi, B.; Kumar, S.; Dereddi, R. R.; Rayabandla, S.; Jesudasan, R. A.

10.1101/285429 — genomics — Posted on 2018-03-24

513 Intraspecific genetic and phenotypic diversity: parallel processes and correlated patterns?

Fourtune, L.; Prunier, J. G.; Mathieu-Begne, E.; Canto, N.; Veyssiere, C.; Loot, G.; Blanchet, S.

10.1101/288357 — evolutionary biology — Posted on 2018-03-24

514 ModulOmics: Integrating Multi-Omics Data to Identify Cancer Driver Modules

Silverbush, D.; Cristea, S.; Yanovich, G.; Geiger, T.; Beerenwinkel, N.; Sharan, R.

10.1101/288399 — cancer biology — Posted on 2018-03-24

515 Reducing effects of particle adsorption to the air-water interface in cryoEM

Noble, A. J.; Wei, H.; Dandey, V. P.; Zhang, Z.; Potter, C. S.; Carragher, B.

10.1101/288340 — biophysics — Posted on 2018-03-24

516 snpAD: An ancient DNA genotype caller

Pruefer, K.

10.1101/288258 — bioinformatics — Posted on 2018-03-24

517 Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state

Lei, H.-T.; Ma, J.; Sanchez-Martinez, S.; Gonen, T.

10.1101/288233 — biochemistry — Posted on 2018-03-24

518 Counteracting estimation bias and social influence to improve the wisdom of crowds

Kao, A. B.; Berdahl, A. M.; Hartnett, A. T.; Lutz, M. J.; Bak-Coleman, J. B.; Ioannou, C. C.; Giam, X.; Couzin, I. D.

10.1101/288191 — animal behavior and cognition — Posted on 2018-03-24

519 Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse

Tomberg, K.; Westrick, R. J.; Kotnik, E. N.; Siemieniak, D. R.; Zhu, G.; Saunders, T. L.; Cleuren, A. C.; Ginsburg, D.

10.1101/174086 — genetics — Posted on 2018-03-24

520 The control of epistemic curiosity in the human brain

Ligneul, R.; Mermillod, M.; Morisseau, T.

10.1101/157644 — neuroscience — Posted on 2018-03-24

521 Thalamostriatal Interactions in Human Reversal Learning

Bell, T.; Langdon, A.; Lindner, M.; Lloyd, W.; Christakou, A.

10.1101/246371 — neuroscience — Posted on 2018-03-24

522 Detection of GBA missense mutations and other variants using the Oxford Nanopore MinION

Leija-Salazar, M.; Sedlazeck, F. J.; Mokretar, K.; Mullin, S.; Toffoli, M.; Athanasopoulou, M.; Donald, A.; Sharma, R.; Hughes, D.; Schapira, A. H.; Proukakis, C.

10.1101/288068 — genetics — Posted on 2018-03-24

523 Spatial sampling in human visual cortex is modulated by both spatial and feature-based attention

van Es, D. M.; Theeuwes, J.; Knapen, T.

10.1101/147223 — neuroscience — Posted on 2018-03-24

524 Rescuing Troves of Data to Tackle Emerging Mosquito-Borne Diseases

Rund, S. S. C.; Martinez, M. E.

10.1101/096875 — ecology — Posted on 2018-03-24

525 Decoding Human Emotional Faces in the Dog’s Brain

Hernandez-Perez, R.; Concha, L.; Cuaya, L. V.

10.1101/134080 — animal behavior and cognition — Posted on 2018-03-24

526 Role of communication network topology in controlling microbial population in consortia

Ren, X.; Murray, R. M.

10.1101/288142 — synthetic biology — Posted on 2018-03-24

527 Can you make morphometrics work when you know the right answer? Pick and mix approaches for apple identification.

Christodoulou, M. D.; Battey, N. H.; Culham, A.

10.1101/288175 — plant biology — Posted on 2018-03-24

528 Cerebellar grey matter volume in adolescence is associated with prodromal psychotic symptoms and norm-violating behavior

Moberget, T.; Alnaes, D.; Kaufmann, T.; Doan, N. T.; Cordova-Palomera, A.; Norbom, L. B.; Rokicki, J.; van der Meer, D.; Andreassen, O. A.; Westlye, L. T.

10.1101/288134 — neuroscience — Posted on 2018-03-23

529 Genome sequencing and assessment of plant growth-promoting properties of a Serratia marcescens strain isolated from vermicompost

Matteoli, F. P.; Passarelli-Araujo, H.; Reis, R. J. A.; da Rocha, L. O.; Souza, E. M.; Aravind, L.; Olivares, F. L.; Venancio, T. M.

10.1101/288084 — microbiology — Posted on 2018-03-23

530 Detection of GBA missense mutations and other variants using the Oxford Nanopore MinION

Leija-Salazar, M.; Sedlazeck, F. J.; Mokretar, K.; Mullin, S.; Toffoli, M.; Athanasopoulou, M.; Donald, A.; Sharma, R.; Hughes, D.; Schapira, A. H.; Proukakis, C.

10.1101/288068 — genetics — Posted on 2018-03-23

531 Cross-species functional modules link proteostasis to human normal aging

Komljenovic, A.; Li, H.; Sorrentino, V.; Kutalik, Z.; Auwerx, J.; Robinson-Rechavi, M.

10.1101/287128 — systems biology — Posted on 2018-03-23

532 SSMART: Sequence-structure motif identification for RNA-binding proteins

Munteanu, A.; Mukherjee, N.; Ohler, U.

10.1101/287953 — bioinformatics — Posted on 2018-03-23

533 AmpUMI: Design and analysis of unique molecular identifiers for deep amplicon sequencing

Clement, K.; Farouni, R.; Bauer, D.; Pinello, L.

10.1101/288118 — bioinformatics — Posted on 2018-03-23

534 Graph Peak Caller: calling ChIP-Seq Peaks on Graph-based Reference Genomes

Grytten, I.; Rand, K. D.; Nederbragt, A. J.; Storvik, G. O.; Glad, I. K.; Sandve, G. K.

10.1101/286823 — bioinformatics — Posted on 2018-03-23

535 A widespread decrease of chromatin accessibility in age-related macular degeneration

Wang, J.; Zibetti, C.; Shang, P.; Sripathi, S. R.; Zhang, P.; Cano, M.; Hoang, T.; Xia, S.; Ji, H.; Merbs, S. L.; Zack, D. J.; Handa, J. T.; Sinha, D.; Blackshaw, S.; Qian, J.

10.1101/264564 — genomics — Posted on 2018-03-23

536 High precision wavefront control in point spread function engineering for single emitter localization

Siemons, M.; Hulleman, C.; Thorsen, R.; Smith, C.; Stallinga, S.

10.1101/267864 — biophysics — Posted on 2018-03-23

537 FastSpar: Rapid and scalable correlation estimation for compositional data

Watts, S. C.; Ritchie, S. C.; Inouye, M.; Holt, K. E.

10.1101/272583 — bioinformatics — Posted on 2018-03-23

538 Topographer Reveals Dynamic Mechanisms of Cell Fate Decisions from Single-Cell Transcriptomic Data

Zhang, J.; Zhou, T.; Nie, Q.

10.1101/251207 — systems biology — Posted on 2018-03-23

539 What is an archaeon and are the Archaea really unique?

Harish, A.

10.1101/256263 — evolutionary biology — Posted on 2018-03-23

540 The maternal effect gene Wds controls Wolbachia titer in Nasonia

Funkhouser-Jones, L. J.; van Opstal, E. J.; Sharma, A.; Bordenstein, S. R.

10.1101/256909 — evolutionary biology — Posted on 2018-03-23

541 The U1 snRNP subunit LUC7 controls plant development and stress response through alternative splicing regulation

de Francisco Amorim, M.; Willing, E.-M.; Francisco-Mangilet, A. G.; Droste-Borel, I.; Macek, B.; Schneeberger, K.; Laubinger, S.

10.1101/150805 — plant biology — Posted on 2018-03-23

542 Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways

Osborn, M. F.; Coles, A. H.; Biscans, A.; Haraszti, R. A.; Roux, L.; Davis, S.; Ly, S.; Echeverria, D.; Hassler, M. R.; Godinho, B. M. D. C.; Nikan, M.; Khvorova, A.

10.1101/288092 — pharmacology and toxicology — Posted on 2018-03-23

543 Dynamics and interactions of highly resolved marine plankton via automated high frequency sampling

Needham, D. M.; Fichot, E. B.; Wang, E.; Berdjeb, L.; Cram, J. A.; Fichot, C. G.; Fuhrman, J. A.

10.1101/216978 — microbiology — Posted on 2018-03-23

544 Dynamic temperature-sensitive A-to-I RNA editing in the brain of a heterothermic mammal during hibernation

Riemondy, K. A.; Gillen, A.; White, E. A.; Bogren, L. K.; Hesselberth, J. R.; Martin, S. L.

10.1101/288159 — genomics — Posted on 2018-03-23

545 Selective maintenance of multiple CRISPR arrays across prokaryotes

Weissman, J. L.; Fagan, W. F.; Johnson, P. L. F.

10.1101/148544 — evolutionary biology — Posted on 2018-03-23

546 Roles of G1 cyclins in the temporal organization of yeast cell cycle - a transcriptome-wide analysis

Teufel, L.; Tummler, K.; Flöttmann, M.; Herrmann, A.; Barkai, N.; Klipp, E.

10.1101/287573 — systems biology — Posted on 2018-03-23

547 Altered function of the glutamate aspartate transporter GLAST in glioblastoma

Pellegatta, S.; Corbetta, C.; Di Ianna, N.; Bruzzone, M. G.; Patane, M.; Pollo, B.; Cantini, G.; Cominelli, M.; Zucca, I.; Pisati, F.; Poliani, P. L.; Finocchiaro, G.

10.1101/287623 — cancer biology — Posted on 2018-03-23

548 Changes In The Axon Initiation Segment Of Thalamic Neurons In Response To Cyclical Stimulation

Kolezeva, Y.; Zirkov, M.

10.1101/287771 — neuroscience — Posted on 2018-03-23

549 Whole-exome sequencing identified rare variants associated with body length and girth in cattle

Chen, Y.; Du, M.; Liu, Y.; Gao, X.; Zhang, W.; Xu, L.; Zhang, L.; Lingyang, X.; Gao, H.; Bo, Z.; Zhao, M.; Li, J.

10.1101/287474 — genetics — Posted on 2018-03-23

550 Neurodynamic explanation of inter-individual and inter-trial variability in cross-modal perception

Kumar, V. G.; Dutta, S.; Talwar, S.; Roy, D.; Banerjee, A.

10.1101/286609 — neuroscience — Posted on 2018-03-23

551 Early identity recognition of familiar faces is not dependent on holistic processing

Mohr, S.; Wang, A.; Engell, A. D.

10.1101/287466 — neuroscience — Posted on 2018-03-23

552 A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo.

Kemaladewi, D.; Bassi, P. S.; Lindsay, K.; Erwood, S.; Hyatt, E.; Place, K. M.; Marks, R.; Gawlik, K. I.; Durbeej, M.; Ivakine, E. A.; Cohn, R. D.

10.1101/286500 — genetics — Posted on 2018-03-23

553 Direct estimation of mutations in great apes reveals significant recent human slowdown in the yearly mutation rate

Besenbacher, S.; Hvilsom, C.; Marques-Bonet, T.; Mailund, T.; Schierup, M. H.

10.1101/287821 — evolutionary biology — Posted on 2018-03-23

554 A taxonomically-restricted Uric Acid transporter provides insight into antioxidant equilibrium

Oliveira, D.; Machado, A.; Cardoso, T.; Lopes-Marques, M.; Castro, L. F.; Ruivo, R.

10.1101/287870 — evolutionary biology — Posted on 2018-03-23

555 Anisotropic Crb accumulation, modulated by Src42A, orients epithelial tube growth in Drosophila

Olivares-Castineira, I.; Llimargas, M.

10.1101/287854 — developmental biology — Posted on 2018-03-23

556 Recombinant expression of Proteorhodopsin and biofilm regulators in Escherichia coli for nanoparticle binding and removal in a wastewater treatment model

Yang, J.; Wei, Y.; Yeh, C.; Liou, F.; Chen, W.; Lu, D.; Chen, C.; Pei, J.; Lee, C.; Chen, E.; Lin, A.; Imbrogulio, P.; Chang, K.; Hu, A.; Kao, J.; Chen, K.; Tei, A.; Yang, C.; Hsu, K.; Hsia, L.; Wallace, O.; Hau, A.; Liu, A.; Huang, W.; Chang, S.; Chang, C.; Tsai, L.; Wang, A.; Lee, C.; Wang, A.; Shah, M.; Yim, L.; Tsao, S.; Chiang, T.; Clapper, J. C.

10.1101/286195 — synthetic biology — Posted on 2018-03-23

557 More is less: increased processing of unwanted memories facilitates forgetting

Wang, T. H.; Placek, K.; Lewis-Peacock, J. A.

10.1101/286534 — neuroscience — Posted on 2018-03-23

558 Impact of Sex and APOE Status on Spatial Navigation in Pre-symptomatic Alzheimer’s disease

Coughlan, G.; Coutrot, A.; Khondoker, M.; Minihane, A. M.; Spiers, H.; Hornberger, M.

10.1101/287722 — neuroscience — Posted on 2018-03-23

559 A Polygenic Score for Higher Educational Attainment is Associated with Larger Brains

Elliott, M. L.; Belsky, D. W.; Anderson, K.; Corcoran, D. L.; Ge, T.; Knodt, A.; Prinz, J. A.; Sugden, K.; Williams, B.; Ireland, D.; Poulton, R.; Caspi, A.; Holmes, A.; Moffitt, T.; Hariri, A. R.

10.1101/287490 — neuroscience — Posted on 2018-03-23

560 Enrichment of gene variants associated with treatable genetic disorders in psychiatric populations

Sriretnakumar, V.; Harripaul, R.; Vincent, J. B.; Kennedy, J. L.; So, J.

10.1101/287219 — genetics — Posted on 2018-03-23

561 On the synchronized failure of global crop production

Mehrabi, Z.; Ramankutty, N.

10.1101/287391 — ecology — Posted on 2018-03-23

562 The Origins and Consequences of Localized and Global Somatic Hypermutation

Yousif, F.; Prokopec, S.; Sun, R. X.; Fan, F.; Lalansingh, C. M.; Park, D. H.; Szyca, L.; PCAWG Network, ; Boutros, P. C.

10.1101/287839 — cancer biology — Posted on 2018-03-23

563 Engineered Peptide Barcodes for In-Depth Analyses of Binding Protein Ensembles

Egloff, P.; Zimmermann, I.; Arnold, F. M.; Hutter, C. A. J.; Morger, D.; Opitz, L.; Poveda, L.; Keserue, H.-A.; Panse, C.; Roschitzki, B.; Seeger, M.

10.1101/287813 — bioengineering — Posted on 2018-03-23

564 Intracranial interictal functional networks predict the effect of subacute cortical stimulation in focal epilepsy

Wang, Y.; Taylor, P. N.; Diaz-Diaz, J.; Selway, R. P.; Valentin, A.; Alarcon, G.; Jimenez-Jimenez, D.

10.1101/288019 — neuroscience — Posted on 2018-03-23

565 A novel time-stamp mechanism transforms egocentric encounters into an allocentric spatial representation

Wallach, A.; Harvey-Girard, E.; Jun, J. J.; Longtin, A.; Maler, L.

10.1101/285494 — neuroscience — Posted on 2018-03-23

566 Model-based Pavlovian control of attention to threat.

Talmi, D.; Slapkova, M.; Wieser, M. J.

10.1101/288027 — neuroscience — Posted on 2018-03-23

567 Dynamic functional connectivity markers of objective trait mindfulness

Lim, J.; Teng, J.; Patanaik, A.; Tandi, J.; Massar, S.

10.1101/287540 — neuroscience — Posted on 2018-03-23

568 Polygenic risk score for schizophrenia is more strongly associated with ancestry than with schizophrenia

Curtis, D.

10.1101/287136 — genetics — Posted on 2018-03-23

569 Low frequency and rare coding variation contributes to multiple sclerosis risk

International Multiple Sclerosis Genetics Consortium, ; Mitrovic, M.; Patsopoulos, N.; Beecham, A.; Dankowski, T.; Goris, A.; Dubois, B.; Dhooghe, M.-B.; Lemmens, R.; Van Damme, P.; Fitzgerald, K.; Bach Sondergaard, H.; Sellebjerg, F.; Sorensen, P. S.; Ullum, H.; Wegner Thoerner, L.; Werge, T.; Saarela, J.; Cournu-Rebeix, I.; Damotte, V.; Fontaine, B.; Guillot-Noel, L.; Lathrop, M.; Vukusik, S.; Gourraud, P.-A.; Andlauer, T.; Pongratz, V.; Buck, D.; Gasperi, C.; Graetz, C.; Bayas, A.; Heesen, C.; Kumpfel, T.; Linker, R.; Paul, F.; Stangel, M.; Tackenberg, B.; Then Bergh, F.; Warnke, C.; Wiend

10.1101/286617 — genetics — Posted on 2018-03-23

570 Evolution favors aging in populations with assortative mating and strong pathogen pressure

Lenart, P.; Bienertova-Vasku, J.; Berec, L.

10.1101/287664 — evolutionary biology — Posted on 2018-03-23

571 Reproductive interference hampers species coexistence despite conspecific sperm precedence

Iritani, R.; Noriyuki, S.

10.1101/287482 — ecology — Posted on 2018-03-23

572 SISS-Geo: Leveraging Citizen Science to Monitor Wildlife Health Risks in Brazil

Chame, M.; Barbosa, H. J. C.; Gadelha, L. M. R.; Augusto, D. A.; Krempser, E.; Abdalla, L.

10.1101/286740 — bioinformatics — Posted on 2018-03-23

573 When to care and when to kill: termites shape their collective response based on stage of infection

Davis, H. E.; Meconcelli, S.; Radek, R.; McMahon, D. P.

10.1101/287441 — animal behavior and cognition — Posted on 2018-03-23

574 Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production

Gabrysova, L.; Mann, E. H.; Bradley, L.; MacRae, J. I.; Whicher, C.; Hawrylowicz, C. M.; Anastasiou, D.; O'Garra, A.

10.1101/287920 — immunology — Posted on 2018-03-23

575 Autoreactive T cells preferentially drive differentiation of non-responsive memory B cells at the expense of germinal center maintenance.

Jain, R. W.; Parham, K. A.; Tesfagiorgis, Y.; Craig, H. C.; Romanchik, E.; Kerfoot, S. M.

10.1101/287789 — immunology — Posted on 2018-03-23

576 A polygenic p factor for major psychiatric disorders

Selzam, S.; Coleman, J. R. I.; Moffitt, T. E.; Caspi, A.; Plomin, R.

10.1101/287987 — genomics — Posted on 2018-03-23

577 An unexpected contribution of lincRNA splicing to enhancer function.

Tan, J. Y.; Biasini, A.; Young, R. S.; Marques, A.

10.1101/287706 — genomics — Posted on 2018-03-23

578 Efficiently inferring the demographic history of many populations with allele count data

Kamm, J. A.; Terhorst, J.; Durbin, R.; Song, Y. S.

10.1101/287268 — evolutionary biology — Posted on 2018-03-23

579 Nach is a novel ancestral subfamily of the CNC-bZIP transcription factors selected during evolution from the marine bacteria to human

Zhu, Y.; Wang, M.; Xiang, Y.; Qiu, L.; Hu, S.; Zhang, Z.; Mattjus, P.; Zhang, Y.

10.1101/287755 — ecology — Posted on 2018-03-23

580 Thrombospondins 1 and 2 affect lysyl oxidase protein and collagen matrix maturation in cortical bone of growing male and female mice via non-redundant pathways

Shearer, D.; Mervis, M. O.; Manley, E.; Reddy, A. B.; Alford, A. I.

10.1101/287763 — cell biology — Posted on 2018-03-23

581 PromoterPredict: sequence-based modelling of Escherichia coli σ70 promoter strength yields logarithmic dependence between promoter strength and sequence

Bharanikumar, R.; R. Premkumar, K. A.; Palaniappan, A.

10.1101/287607 — bioinformatics — Posted on 2018-03-23

582 Conservation and Divergence of YODA MAPKKK Function in Regulation of Grass Epidermal Patterning

Abrash, E.; Anleu Gil, M. X.; Matos, J. L.; Bergmann, D. C.

10.1101/287433 — plant biology — Posted on 2018-03-23

583 RAD51 paralogs regulate double strand break repair pathway choice by limiting Ku complex retention

Mejias-Navarro, F.; Gomez-Cabello, D.; Huertas, P.

10.1101/282855 — molecular biology — Posted on 2018-03-23

584 Social communication between microbes colonizing the social honey bee Apis mellifera

Newton, I.; Miller, K. I.; Franklin, C. D.; Mattila, H. R.

10.1101/287995 — microbiology — Posted on 2018-03-23

585 Horizontal transfer and proliferation of Tsu4 in Saccharomyces paradoxus.

Bergman, C. M.

10.1101/287078 — evolutionary biology — Posted on 2018-03-23

586 Molecular Modeling Suggests Homologous 2-APB Binding Sites in Connexins 26 and 32

Comollo, T. W.

10.1101/287326 — pharmacology and toxicology — Posted on 2018-03-23

587 Inhibition of norepinephrine signaling during a sensitive period disrupts locus coeruleus circuitry and emotional behaviors in adulthood

Meng, Q.; Garcia-Garcia, A. L.; Dranovsky, A.; Leonardo, E. D.

10.1101/287243 — neuroscience — Posted on 2018-03-23

588 Lipid utilization in skeletal muscle cells is modulated in vitro and in vivo by specific miRNAs

Chemello, F.; Grespi, F.; Zulian, A.; Cancellara, P.; Hebert-Chatelain, E.; Martini, P.; Bean, C.; Alessio, E.; Ferrazza, R.; Laveder, P.; Guella, G.; Reggiani, C.; Romualdi, C.; Bernardi, P.; Scorrano, L.; Cagnin, S.; Lanfranchi, G.

10.1101/288035 — genomics — Posted on 2018-03-23

589 Urothelial organoids originate from Cd49f-High stem cells and display Notch-dependent differentiation capacity

Real, F. X.; Santos, C. P.; Lapi, E.; Alvaro-Espinosa, L.; Fernandez-Barral, A.; Barbachano, A.; Megias, D.; Munoz, A.

10.1101/287979 — cell biology — Posted on 2018-03-23

590 Influence of SNF1 complex on growth, glucose metabolism and mitochondrial respiration of Saccharomyces cerevisiae

Martinez-Ortiz, C.; Carrillo-Garmendia, A.; Correa-Romero, B. F.; Canizal-Garcia, M.; Gonzalez-Hernandez, J. C.; Regalado-Gonzalez, C.; Olivares-Marin, I. K.; Madrigal-Perez, L. A.

10.1101/287961 — biochemistry — Posted on 2018-03-23

591 Cross-species functional modules link proteostasis to human normal aging

Komljenovic, A.; Li, H.; Kutalik, Z.; Auwerx, J.; Robinson-Rechavi, M.; Sorrentino, V.

10.1101/287128 — systems biology — Posted on 2018-03-23

592 Tuning gene expression variability and multi-gene regulation by dynamic transcription factor control

Benzinger, D.; Khammash, M.

10.1101/287565 — synthetic biology — Posted on 2018-03-23

593 Obesity blocks oligodendrocyte precursor cell differentiation and impedes repair after white matter stroke

Xiao, G.; Burguet, J.; Kawaguchi, R.; Havton, L. A.; Hinman, J. D.

10.1101/283184 — neuroscience — Posted on 2018-03-23

594 Ldb1 mediates trans enhancement in mammals

Monahan, K.; Horta, A.; Mumbay-Wafula, A.; Li, L.; Zhao, Y.; Love, P.; Lomvardas, S.

10.1101/287524 — genomics — Posted on 2018-03-23

595 Transcriptional read-through of the long non-coding RNA SVALKA governs plant cold acclimation

Kindgren, P.; Ard, R.; Ivanov, M.; Marquardt, S.

10.1101/287946 — genomics — Posted on 2018-03-23

596 Complex haplotypes of metabolizing GSTM1 gene deletion harbors signatures of a selective sweep in East Asian populations

Saitou, M.; Satta, Y.; Gokcumen, O.

10.1101/287417 — genetics — Posted on 2018-03-23

597 Non-productive Binding Modes as a Prominent Feature of Aβ1-40 Fiber Elongation: Insights from Molecular Dynamics Simulation

Kar, R. K.; brender, j.; Ghosh, A.; Bhunia, A.

10.1101/287383 — biophysics — Posted on 2018-03-23

598 TETyper: a bioinformatic pipeline for classifying variation and genetic contexts of transposable elements from short-read whole-genome sequencing data

Sheppard, A. E.; Stoesser, N.; German-Mesner, I.; Vegesana, K.; Walker, A. S.; Crook, D. W.; Mathers, A. J.

10.1101/288001 — bioinformatics — Posted on 2018-03-23

599 A Metagenomic Meta-Analysis Reveals Functional Signatures of Health and Disease in the Human Gut Microbiome

Armour, C. R.; Nayfach, S.; Pollard, K.; Sharpton, T. J.

10.1101/286419 — bioinformatics — Posted on 2018-03-23

600 Detecting archaic introgression without archaic reference genomes

Skov, L.; Hui, R.; Hobolth, A.; Scally, A.; Schierup, M. H.; Durbin, R.

10.1101/283606 — evolutionary biology — Posted on 2018-03-23

601 Transcriptional control and exploitation of an immune-responsive family of retrotransposons in Arabidopsis

Zervudacki, J.; Yu, A.; Amesefe, D.; Wang, J.; Drouaud, J.; Navarro, L.; Deleris, A.

10.1101/206813 — plant biology — Posted on 2018-03-23

602 Mavacamten stabilizes the auto-inhibited state of two-headed cardiac myosin

Rohde, J. A.; Thomas, D. D.; Muretta, J. M.

10.1101/287425 — biophysics — Posted on 2018-03-23

603 N6 -methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi’s sarcoma-associated herpesvirus infection

Hesser, C.; Karijolich, J.; Dominissini, D.; He, C.; Glaunsinger, B. A.

10.1101/201475 — microbiology — Posted on 2018-03-23

604 Quantifying biases in test-negative studies of vaccine effectiveness

Lewnard, J. A.; Tedijanto, C.; Cowling, B. J.; Lipsitch, M.

10.1101/237503 — epidemiology — Posted on 2018-03-23

605 Exploring the single-cell RNA-seq analysis landscape with the scRNA-tools database

Zappia, L.; Phipson, B.; Oshlack, A.

10.1101/206573 — bioinformatics — Posted on 2018-03-23

606 Spatial and Temporal Changes in Habitat Heterogeneity Promote Partition of Resources by Syntopic Small Mammals in a Midlatitude Temperate Forest

De la Cruz-Arguello, I. M.; Castro-Campillo, A.; Zavala-Hurtado, A.; Salame-Mendez, A.; Ramirez-Pulido, J.

10.1101/278390 — ecology — Posted on 2018-03-23

607 Astrocytes integrate and drive neural activity

Deemyad, T.; Lüthi, J.; Spruston, N.

10.1101/282764 — neuroscience — Posted on 2018-03-23

608 Ant nurse workers exhibit behavioral and transcriptomic signatures of specialization on larval stage

Walsh, J. T.; Warner, M. R.; Kase, A.; Cushing, B. J.; Linksvayer, T. A.

10.1101/218834 — evolutionary biology — Posted on 2018-03-23

609 Transcriptome Landscape of Human Oocytes and Granulosa Cells Throughout Folliculogenesis

Zhang, Y.; Yan, Z.; Qing, Q.; Nisenblat, V.; Yu, Y.; Wang, T.; Lu, C.; Yang, M.; Yang, S.; Yao, Y.; Zhu, X.; Xia, X.; Dang, Y.; Ren, Y.; Yuan, P.; Li, R.; Liu, P.; Guo, H.; Han, J.; He, H.; Wu, Y.; Li, M.; Zhang, K.; Wang, Y.; Qiao, J.; Yan, J.; Yan, L.

10.1101/285445 — cell biology — Posted on 2018-03-23

610 Expression of fatty acid transport protein in retinal pigment cells promotes lipid droplet expansion and photoreceptor homeostasis

van den Brink, D.; Cubizolle, A.; Chatelain, G.; Napoletano, F.; Dourlen, P.; Davoust, N.; Guillou, L.; Angebault-Prouteau, C.; Bernoud-Hubac, N.; Guichardant, M.; Brabet, P.; Mollereau, B.

10.1101/287672 — cell biology — Posted on 2018-03-23

611 Nanoscale spatio-temporal diffusion modes measured by simultaneous confocal and STED imaging

Schneider, F.; Waithe, D.; Galiani, S.; Bernardino de la Serna, J.; Sezgin, E.; Eggeling, C.

10.1101/287680 — biophysics — Posted on 2018-03-23

612 Kinetic analysis methods applied to single motor protein trajectories

Nord, A.; Pols, A. F.; Depken, M.; Pedaci, F.

10.1101/287748 — biophysics — Posted on 2018-03-23

613 Stabilising and destabilising kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends

Meadows, J. C.; Messin, L. J.; Kamnev, A.; Lancaster, T. C.; Balasubramanian, M. K.; Cross, R. A.; Millar, J. B. A.

10.1101/287649 — cell biology — Posted on 2018-03-23

614 Signatures of insecticide selection in the genome of Drosophila melanogaster.

Duneau, D.; Haina, S.; Revah, J.; San Miguel, K.; Kunerth, H. D.; Calvas, I. V.; Messer, P. W.; Scott, J.; Buchon, N.

10.1101/287250 — evolutionary biology — Posted on 2018-03-23

615 DNA metabarcoding from sample fixative as a quick and voucher preserving biodiversity assessment method

Zizka, V. M. A.; Leese, F.; Peinert, B.; Geiger, M. F.

10.1101/287276 — molecular biology — Posted on 2018-03-23

616 Methylthioadenosine reduces host inflammatory response by suppressing Salmonella virulence

Bourgeois, J. S.; Zhou, D.; Thurston, T. L. M.; Gilchrist, J. J.; Ko, D.

10.1101/287052 — microbiology — Posted on 2018-03-23

617 Cell type-specific interchromosomal interactions as a mechanism for transcriptional diversity

Horta, A.; Monahan, K.; Bashkirova, L.; Lomvardas, S.

10.1101/287532 — genomics — Posted on 2018-03-23

618 Human activity is altering the world’s zoogeographical regions

Bernardo-Madrid, R.; Calatayud, J.; Gonzalez-Suarez, M.; Rosvall, M.; Lucas, P. M.; Rueda, M.; Antonelli, A.; Revilla, E.

10.1101/287300 — ecology — Posted on 2018-03-23

619 Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain

Radulescu, E.; Jaffe, A. E.; Straub, R. E.; Chen, Q.; Shin, J. H.; Hyde, T. M.; Kleinman, J. E.; Weinberger, D. R.

10.1101/286559 — neuroscience — Posted on 2018-03-23

620 Genomic analysis of Acinetobacter baumannii prophages reveals remarkable diversity and suggests profound impact on bacterial virulence and fitness

Costa, A. R.; Monteiro, R.; Azeredo, J.

10.1101/286476 — microbiology — Posted on 2018-03-23

621 Divergent gene expression among phytoplankton taxa in response to upwelling

Lampe, R. H.; Cohen, N. R.; Ellis, K. A.; Bruland, K. W.; Maldonado, M. T.; Peterson, T. D.; Till, C. P.; Brzezinski, M. A.; Bargu, S.; Thamatrakoln, K.; Kuzminov, F. I.; Twining, B. S.; Marchetti, A.

10.1101/286138 — microbiology — Posted on 2018-03-23

622 MAIT cells contribute to protection against lethal influenza infection in vivo

van Wilgenburg, B.; Loh, L.; Chen, Z.; Pediongco, T. J.; Wang, H.; Shi, M.; Zhao, Z.; Koutsakos, M.; Nussing, S.; Sant, S.; Wang, Z.; D'Souza, C.; Almeida, C. F.; Kostenko, L.; Eckle, S. B.; Meehan, B. S.; Godfrey, D. I.; Reading, P. C.; Corbett, A. J.; McCluskey, J.; Klenerman, P.; Kedzierska, K.; Hinks, T.

10.1101/247205 — immunology — Posted on 2018-03-23

623 Lost in translation: egg transcriptome reveals molecular signature to predict developmental success and novel maternal-effect genes

Cheung, C. T.; Nguyen, T.; Le Cam, A.; Patinote, A.; Journot, L.; Reynes, C.; Bobe, J.

10.1101/286815 — genomics — Posted on 2018-03-23

624 Rhizosphere bacterial community composition depends on plant diversity legacy in soil and plant species identity

Schmid, M. W.; Hahl, T.; van Moorsel, S. J.; Wagg, C.; De Deyn, G. B.; Schmid, B.

10.1101/287235 — ecology — Posted on 2018-03-23

625 Full-length de novo viral quasispecies assembly through variation graph construction

Baaijens, J.; van der Roest, B.; Koester, J.; Stougie, L.; Schoenhuth, A.

10.1101/287177 — bioinformatics — Posted on 2018-03-23

626 Survival of the simplest: the cost of complexity in microbial evolution

Held, T.; Klemmer, D.; Lässig, M.

10.1101/287599 — evolutionary biology — Posted on 2018-03-23

627 A naturally-occurring dominant-negative competitor of Keap1 against its inhibition of Nrf2

Qiu, L.; Wang, M.; Zhu, Y.; Xiang, Y.; Zhang, Y.

10.1101/286997 — molecular biology — Posted on 2018-03-23

628 A Novel Mouse Model of Campylobacter jejuni Enteropathy and Diarrhea

Giallourou, N.; Medlock, G. L.; Bolick, D. T.; Medeiros, P. H.; Ledwaba, S. E.; Kolling, G. L.; Tung, K.; Guerry, P.; Swann, J. R.; Guerrant, R. L.

10.1101/283572 — microbiology — Posted on 2018-03-22

629 Mitotic progression, arrest, exit or death is determined by centromere integrity and independent of de novo transcription

Cruz, M.; Alba Fernandez, M.; van Ijcken, W.; Galjart, N.; Arulanandam, A. J.; Maiato, H.; Ferras, C.

10.1101/287151 — cell biology — Posted on 2018-03-22

630 Mavacamten stabilizes the auto-inhibited state of two-headed cardiac myosin

Rohde, J. A.; Thomas, D. D.; Muretta, J. M.

10.1101/287425 — biophysics — Posted on 2018-03-22

631 The Drosophila microbiome has a limited influence on sleep, activity, and courtship behaviors

Selkrig, J.; Mohammad, F.; Ng, S. H.; Chua, J. Y.; Tumkaya, T.; Ho, J.; Chiang, Y. N.; Rieger, D.; Pettersson, S.; Helfrich-Foerster, C.; Yew, J.; Claridge-Chang, A.

10.1101/287045 — neuroscience — Posted on 2018-03-22

632 Optical activation of TrkA signaling

Duan, L.; Hope, J. M.; Guo, S.; Ong, Q.; Francois, A.; Kaplan, L.; Scherrer, G.; Cui, B.

10.1101/287409 — synthetic biology — Posted on 2018-03-22

633 How do blind people represent rainbows? Disentangling components of conceptual representations.

Striem-Amit, E.; Wang, X.; Bi, Y.; Caramazza, A.

10.1101/287318 — neuroscience — Posted on 2018-03-22

634 Iteratively Improving Hi-C Experiments One Step at a Time

Golloshi, R.; Sanders, J. T.; McCord, R. P.

10.1101/287201 — genomics — Posted on 2018-03-22

635 An aged human heart tissue model showing age-related molecular and functional deterioration resembling the native heart

Acun, A.; Nguyen, T. D.; Zorlutuna, P.

10.1101/287334 — bioengineering — Posted on 2018-03-22

636 Engineering targeted deletions in the mitochondrial genome

Campbell, J. M.; Perales Clemente, E.; Ata, H.; Vidal Folch, N.; Lui, W.; Clark, K. J.; Xu, X.; Oglesbee, D.; Nelson, T. J.; Ekker, S. C.

10.1101/287342 — molecular biology — Posted on 2018-03-22

637 FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells

Tomida, J.; Takata, K.-i.; Bhetawal, S.; Person, M. D.; Chao, H.-P.; Tang, D. G.; Wood, R. D.

10.1101/287375 — molecular biology — Posted on 2018-03-22

638 Comparative Genomics and Genome Evolution in Birds-of-paradise

Prost, S.; Armstrong, E. E.; Nylander, J.; Thomas, G. W. C.; Suh, A.; Petersen, B.; Dalen, L.; Benz, B.; Blom, M. P. K.; Palkopoulou, E.; Ericson, P. G. P.; Irestedt, M.

10.1101/287086 — genomics — Posted on 2018-03-22

639 MicroRNA-202 (miR-202) controls female fecundity by regulating medaka oogenesis

Gay, S.; Bugeon, J.; Bouchareb, A.; Henry, L.; Montfort, J.; Le Cam, A.; Bobe, J.; Thermes, V.

10.1101/287359 — genetics — Posted on 2018-03-22

640 Cryo-EM structure of the polycystin 2-l1 ion channel

Hulse, R. E.; Li, Z.; Huang, R. K.; Zhang, J.; Clapham, D. E.

10.1101/287367 — biophysics — Posted on 2018-03-22

641 Reference-based annotation of single-cell transcriptomes identifies a profibrotic macrophage niche after tissue injury

Aran, D.; Looney, A. P.; Liu, L.; Fong, V.; Hsu, A.; Wolters, P. J.; Abate, A.; Butte, A. J.; Bhattacharya, M.

10.1101/284604 — immunology — Posted on 2018-03-22

642 Quantifying the unquantifiable: why Hymenoptera -- not Coleoptera -- is the most speciose animal order

Forbes, A. A.; Bagley, R. K.; Beer, M. A.; Hippee, A. C.; Widmayer, H. A.

10.1101/274431 — zoology — Posted on 2018-03-22

643 A novel microtubule nucleation pathway for meiotic spindle assembly in oocytes

ROME, P.; OHKURA, H.

10.1101/284901 — cell biology — Posted on 2018-03-22

644 Time dependence of cellular responses to dynamic and complex strain fields

Chagnon-Lessard, S.; Godin, M.; Pelling, A. E.

10.1101/286625 — cell biology — Posted on 2018-03-22

645 Complex Interplay between Serum and Fibroblasts in 3D Hepatocyte Co-culture

Mittal, N.; Li, H.; Ananthanarayanan, A.; Yu, H.

10.1101/286088 — cell biology — Posted on 2018-03-22

646 Crystallographic observation of nonenzymatic RNA primer extension

Szostak, J. W.; Zhang, W.; Walton, T.; Li, L.

10.1101/287102 — biochemistry — Posted on 2018-03-22

647 Hierarchical modeling of the effect of pre-exposure prophylaxis on HIV in the US

Dale, R.; Chen, Y.; He, H.

10.1101/285940 — epidemiology — Posted on 2018-03-22

648 Comparison of ultracentrifugation and a commercial kit for isolation of exosomes derived from glioblastoma and breast cancer cell lines

Skottvoll, F. S.; Berg, H. E.; Bjorseth, K.; Lund, K.; Roos, N.; Bekhradnia, S.; Thiede, B.; Roberg-Larsen, H.; Nystrom, B.; Lundanes, E.; Wilson, S. R.

10.1101/274910 — biochemistry — Posted on 2018-03-22

649 Learning naturalistic temporal structure in the posterior medial network

Aly, M.; Chen, J.; Turk-Browne, N. B.; Hasson, U.

10.1101/196287 — neuroscience — Posted on 2018-03-22

650 Retrograde Transport and ATG-4.2-Mediated Maturation Cooperate to Remove Autophagosomes from the Synapse

Hill, S. E.; Colon-Ramos, D.

10.1101/287144 — cell biology — Posted on 2018-03-22

651 Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators

Hommel, B.; Mukaremera, L.; Cordero, R. J. B.; coelho, C.; Desjardins, C. A.; Sturny-Leclere, A.; Janbon, G.; Perfect, J.; Fraser, J. A.; Casadevall, A.; Cuomo, C. A.; Dromer, F.; Nielsen, K.; Alanio, A.

10.1101/191668 — microbiology — Posted on 2018-03-22

652 An Evaluation of Machine-learning for Predicting Phenotype: Studies in Yeast, Rice and Wheat

Grinberg, N. F.; Orhobor, O. I.; King, R. D.

10.1101/105528 — bioinformatics — Posted on 2018-03-22

653 Naked mole-rat transcriptome signatures of socially-suppressed sexual maturation and links of reproduction to aging

Bens, M.; Szafranski, K.; Holtze, S.; Sahm, A.; Groth, M.; Kestler, H. A.; Hildebrandt, T. B.; Platzer, M.

10.1101/221333 — systems biology — Posted on 2018-03-22

654 Auxiliary ATP binding sites power rapid unwinding by RecBCD

Zananiri, R.; Gaydar, V.; Yahalom, D.; Malik, O.; Rudnizky, S.; Kaplan, A.; Henn, A.

10.1101/210823 — biophysics — Posted on 2018-03-22

655 Crumble: reference free lossy compression of sequence quality values

Bonfield, J. K.; McCarthy, S. A.; Durbin, R. A.

10.1101/243030 — bioinformatics — Posted on 2018-03-22

656 Sequence-directed action of RSC remodeler and pioneer factors positions +1 nucleosome to facilitate transcription

Kubik, S.; O'Duibhir, E.; de Jonge, W.; Mattarocci, S.; Albert, B.; Falcone, J.-L.; Bruzzone, M. J.; Holstege, F. C. P.; Shore, D.

10.1101/266072 — molecular biology — Posted on 2018-03-22

657 A quantitative map of human Condensins provides new insights into mitotic chromosome architecture

Walther, N.; Hossain, M. J.; Politi, A. Z.; Koch, B.; Kueblbeck, M.; Oedegaard-Fougner, O.; Lampe, M.; Ellenberg, J.

10.1101/237834 — cell biology — Posted on 2018-03-22

658 Modelling cell-cell interactions from spatial molecular data with spatial variance component analysis

Arnol, D.; Schapiro, D.; Bodenmiller, B.; Saez-Rodriguez, J.; Stegle, O.

10.1101/265256 — bioinformatics — Posted on 2018-03-22

659 diploS/HIC: an updated approach to classifying selective sweeps

Kern, A. D.; Schrider, D. R.

10.1101/267229 — evolutionary biology — Posted on 2018-03-22

660 FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data

Scholz, C. J.; Biernat, P.; Becker, M.; Bassler, K.; Günther, P.; Balfer, J.; Dickten, H.; Flöer, L.; Heikamp, K.; Angerer, P.; Heilig, M.; Karle, R.; Köhler, M.; Mazurkiewicz, T.; Mönnighoff, M.; Sauer, C.; Schick, A.; Schlemm, G.; Weigelt, R.; Winkler, M.; Ulas, T.; Theis, F.; Huthmacher, S.; Kratsch, C.; Schultze, J. L.

10.1101/272476 — bioinformatics — Posted on 2018-03-22

661 BioFeatureFinder: Flexible, unbiased analysis of biological characteristics associated with genomic regions

Ciamponi, F. E.; Lovci, M. T.; Cruz, P. R.; Massirer, K. B.

10.1101/279612 — bioinformatics — Posted on 2018-03-22

662 High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions

Aprianto, R.; Slager, J.; Holsappel, S.; Veening, J.-W.

10.1101/283739 — microbiology — Posted on 2018-03-22

663 Mechanisms for European Bat Lyssavirus subtype 1 persistence in non-synanthropic bats: insights from a modeling study

Colombi, D.; Serra Cobo, J.; Metras, R.; Apolloni, A.; Poletto, C.; Lopez-Roig, M.; Bourhy, H.; Colizza, V.

10.1101/283564 — epidemiology — Posted on 2018-03-22

664 Developmental genetics in a complex adaptive structure, the weevil rostrum

Davis, S.

10.1101/287185 — developmental biology — Posted on 2018-03-22

665 Retrograde Transport and ATG-4.2-Mediated Maturation Cooperate to Remove Autophagosomes from the Synapse

Hill, S. E.; Colon-Ramos, D.

10.1101/287144 — cell biology — Posted on 2018-03-22

666 Cochaperones enable Hsp70 to fold proteins like a Maxwell’s demon

Xu, H.

10.1101/283143 — biophysics — Posted on 2018-03-22

667 Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39

Slager, J.; Aprianto, R.; Veening, J.-W.

10.1101/283663 — microbiology — Posted on 2018-03-22

668 Sequential regulatory activity prediction across chromosomes with convolutional neural networks

Kelley, D. R.; Reshef, Y. A.; Bileschi, M.; Belanger, D.; McLean, C.; Snoek, J.

10.1101/161851 — genomics — Posted on 2018-03-22

669 Value Representations in Orbitofrontal Cortex Drive Learning, not Choice

Miller, K. J.; Botvinick, M. M.; Brody, C. D.

10.1101/245720 — neuroscience — Posted on 2018-03-22

670 Cell-to-cell heterogeneity in p38-mediated cross-inhibition of JNK causes stochastic cell death

Miura, H.; Kondo, Y.; Matsuda, M.; Aoki, K.

10.1101/151852 — cell biology — Posted on 2018-03-22

671 Phylogeny-corrected identification of microbial gene families relevant to human gut colonization

Bradley, P. H.; Nayfach, S.; Pollard, K. S.

10.1101/189795 — bioinformatics — Posted on 2018-03-22

672 Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

Yengo, L.; Sidorenko, J.; Kemper, K. E.; Zheng, Z.; Wood, A. R.; Weedon, M. N.; Frayling, T. M.; Hirschhorn, J.; Yang, J.; Visscher, P. M.; GIANT Consortium,

10.1101/274654 — genetics — Posted on 2018-03-22

673 Fasting prevents hypoxia-induced defects of proteostasis in C. elegans

Iranon, N. N.; Jochim, B. E.; Miller, D. L.

10.1101/278671 — physiology — Posted on 2018-03-22

674 A chemoproteomic portrait of the oncometabolite fumarate

Kulkarni, R. A.; Bak, D. W.; Wei, D.; Bergholtz, S. E.; Briney, C. A.; Shrimp, J. H.; Thorpe, A. L.; Bavari, A.; Alpsoy, A.; Levy, M.; Florens, L.; Washburn, M. P.; Dykhuizen, E. C.; Frizzell, N.; Weerapana, E.; Linehan, W. M.; Meier, J. L.

10.1101/285759 — cancer biology — Posted on 2018-03-22

675 Impact of antimicrobial treatment for acute otitis media on carriage dynamics of penicillin-susceptible and penicillin non-susceptible Streptococcus pneumoniae: secondary analysis of a randomized, double-blind, placebo-controlled trial

Lewnard, J. A.; Tähtinen, P. A.; Laine, M. K.; Lindholm, L.; Jalava, J.; Huovinen, P.; Lipsitch, M.; Ruohola, A.

10.1101/236752 — epidemiology — Posted on 2018-03-22

676 Insulin Signaling-independent Activation of DAF-16 Shapes the Transcriptome during Normal Aging

Li, S.-T.; Zhao, H.-Q.; Zhang, P.; Liang, C.-Y.; Zhang, Y.-P.; Hsu, A.-L.; Dong, M.-Q.

10.1101/284083 — systems biology — Posted on 2018-03-22

677 Weak and equally balanced synaptic inputs to interneurons in the CA1 hippocampus characterize in vivo rhythmic states

Guet-McCreight, A.; Skinner, F. K.

10.1101/286369 — neuroscience — Posted on 2018-03-22

678 Increased posterior default mode network activity and structural connectivity in young adult APOE-ε4 carriers: a multi-modal imaging investigation

Hodgetts, C. J.; Shine, J. P.; Williams, H.; Postans, M.; Sims, R.; Williams, J.; Lawrence, A. D.; Graham, K. S.

10.1101/285536 — neuroscience — Posted on 2018-03-22

679 Symbiosis-related genes sustain the development of a downy mildew pathogen on Arabidopsis thaliana

Ried, M. K.; Banhara, A.; Binder, A.; Hwu, F.-H.; Gust, A. A.; Höfle, C.; Hückelhoven, R.; Nürnberger, T.; Parniske, M.

10.1101/286872 — cell biology — Posted on 2018-03-22

680 Intronic miRNA Mediated Gene Expression Regulation Controls Protein Crowding Inside the Cell

Sinha, P.; Jaiswal, P.; Jainarayanan, A. K.; Brahmachari, S. K.

10.1101/286906 — bioinformatics — Posted on 2018-03-22

681 Transcription-dependent regulation of replication dynamics modulates genome stability

Blin, M.; Le Tallec, B.; Nahese, V.; Schmidt, M.; Millot, G. A.; Prioleau, M.-N.; Debatisse, M.

10.1101/286807 — molecular biology — Posted on 2018-03-22

682 Real-time analysis and visualization of pathogen sequence data

Neher, R.; Bedford, T.

10.1101/286187 — microbiology — Posted on 2018-03-22

683 The Evolutionary Moulding in plant-microbial symbiosis: matching population diversity of rhizobial nodA and legume NFR5 genes

Igolkina, A. A.; Bazykin, G. A.; Chizhevskaya, E. P.; Provorov, N. A.; Andronov, E. E.

10.1101/285882 — evolutionary biology — Posted on 2018-03-22

684 Evolutionary stability of plant-pollinator networks: efficient communities, hysteresis, and a pollination dilemma

Metelmann, S.; Sakai, S.; Kondoh, M.; Telschow, A.

10.1101/286294 — ecology — Posted on 2018-03-22

685 How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion

Chao, L. H.; Jang, J.; Johnson, A.; Nguyen, A.; Gray, N. S.; Yang, P. L.; Harrison, S. C.

10.1101/286955 — biophysics — Posted on 2018-03-22

686 Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

Nakane, T.; Kimanius, D.; Lindahl, E.; Scheres, S. H. W.

10.1101/286856 — biophysics — Posted on 2018-03-22

687 Smart Region-Growing: a novel algorithm for the segmentation of 3D clarified confocal image stacks

Callara, A.; Magliaro, C.; Ahluwalia, A.; Vanello, N.

10.1101/287029 — bioinformatics — Posted on 2018-03-22

688 Scute structure reveals sex of juvenile and young sturgeon in caviar aquaculture technology

Barulin, N.

10.1101/286401 — zoology — Posted on 2018-03-22

689 Overexpression of RsMYB1 enhances heavy metal stress tolerance in transgenic petunia by elevating the transcript levels of stress tolerant and antioxidant genes

Ai, T. N.; Naing, A. H.; Yun, B.-W.; Kim, C. K.

10.1101/286849 — plant biology — Posted on 2018-03-22

690 Arabidopsis thaliana egy2 mutants display altered expression level of genes encoding crucial photosystem II proteins

Adamiec, M.; Misztal, L.; Kosicka, E.; Paluch-Lubawa, E.; Lucinski, R.

10.1101/286948 — plant biology — Posted on 2018-03-22

691 Disrupted neural adaptation in autism spectrum disorder

Millin, R.; Kolodny, T.; Flevaris, A. V.; Kale, A. M.; Schallmo, M.-P.; Gerdts, J.; Bernier, R. A.; Murray, S.

10.1101/286880 — neuroscience — Posted on 2018-03-22

692 In vivo pulse-labeling of isochronic cohorts of cells in the central nervous system using FlashTag

Govindan, S.; Oberst, P.; Jabaudon, D.

10.1101/286831 — neuroscience — Posted on 2018-03-22

693 Ancient Fennoscandian genomes reveal origin and spread of Siberian ancestry in Europe

Lamnidis, T. C.; Majander, K.; Jeong, C.; Salmela, E.; Wessman, A.; Moiseyev, V.; Khartanovich, V.; Balanovsky, O.; Ongyerth, M.; Weihmann, A.; Sajantila, A.; Kelso, J.; Pääbo, S.; Onkamo, P.; Haak, W.; Krause, J.; Schiffels, S.

10.1101/285437 — genomics — Posted on 2018-03-22

694 Agricultural fungicides inadvertently influence the fitness of Colorado potato beetles, Leptinotarsa decemlineata, and their susceptibility to insecticides

Clements, J.; Schoville, S.; Clements, A.; Amezian, D.; Davis, T.; Sanchez-Sedillo, B.; Bradfield, C.; Huseth, A.; Groves, R.

10.1101/286377 — ecology — Posted on 2018-03-22

695 Preclinical Study: Sunitinib-suppressed MiR-452-5p Facilitates Renal Cancer Cell Invasion and Metastasis Through Modulating SMAD4/SMAD7/EMT Signals

Zhai, W.; Li, S.; Zhang, J.; Chen, Y.; Ma, J.; Kong, W.; Gong, D.; Zheng, J.; Xue, W.; Xu, Y.

10.1101/286898 — cancer biology — Posted on 2018-03-22

696 Gene2Vec: Distributed Representation of Genes Based on Co-Expression

Du, J.; Jia, P.; Dai, Y.; Tao, C.; Zhao, Z.; Zhi, D.

10.1101/286096 — bioinformatics — Posted on 2018-03-22

697 Perturbed functional networks in Alzheimers Disease reveal opposing roles for TGIF and EGR3

Canchi, S.; Raao, B.; Masliah, D.; Rosenthal, S. B.; Sasik, R.; Fisch, K. M.; Jager, P. D.; Bennett, D. A.; Rissman, R. A.

10.1101/286674 — bioinformatics — Posted on 2018-03-22

698 Evidence for a potential role of miR-1908-5p and miR-3614-5p in autoimmune disease risk using genome-wide analyses

Wohlers, I.; Bertram, L.; Lill, C.

10.1101/286260 — bioinformatics — Posted on 2018-03-22

699 Purge Haplotigs: Synteny Reduction for Third-gen Diploid Genome Assemblies

Roach, M. J.; Schmidt, S. A.; Borneman, A. R.

10.1101/286252 — bioinformatics — Posted on 2018-03-22

700 The Claustrum Coordinates Cortical Slow-Wave Activity

Narikiyo, K.; Mizuguchi, R.; Ajima, A.; Mitsui, S.; Shiozaki, M.; Hamanaka, H.; Johansen, J. P.; Mori, K.; Yoshihara, Y.

10.1101/286773 — neuroscience — Posted on 2018-03-22

701 The Functional effects of voluntary and involuntary visual phantom color on conscious awareness

Chang, S.; Pearson, J.

10.1101/286716 — neuroscience — Posted on 2018-03-22

702 Individual differences in response precision correlate with adaptation bias

Mattar, M. G.; Carter, M. V.; Zebrowitz, M. S.; Thompson-Schill, S. L.; Aguirre, G. K.

10.1101/285973 — neuroscience — Posted on 2018-03-22

703 Topological linkage disequilibrium calculated from coalescent genealogies

Wirtz, J.; Rauscher, M.; Wiehe, T.

10.1101/286393 — evolutionary biology — Posted on 2018-03-22

704 Temperature explains broad patterns of Ross River virus transmission across Australia

Shocket, M. S.; Ryan, S. J.; Mordecai, E. A.

10.1101/286724 — ecology — Posted on 2018-03-22

705 Microtubule end tethering of a processive Kinesin-8 motor Kif18b is required for spindle positioning

McHugh, T.; Gluszek-Kustusz, A.; Welburn, J.

10.1101/286658 — cell biology — Posted on 2018-03-22

706 Common antigenic motif recognized by human VH5-51/VL4-1 tau antibodies with distinct functionalities

Apetri, A. C.; Crespo, R.; Juraszek, J.; Pascual, G.; Janson, R.; Zhu, X.; Keogh, E.; Zhang, H.; Holland, T.; Wadia, J.; Verveen, H.; Siregar, B.; Mrosek, M.; Taggenbrock, R.; van Ameijde, J.; Inganas, H.; van Winsen, M.; Koldijk, M.; Zuijdgeest, D.; Borgers, M.; Dockx, K.; Stoop, E.; Yu, W.; Brinkman-van der Linden, E. C.; Ummenthum, K.; van Kolen, K.; Mercken, M.; Steinbacher, S.; de Marco, D.; Hoozemans, J. J.; Wilson, I. A.; Koudstaal, W.; Goudsmit, J.

10.1101/287003 — neuroscience — Posted on 2018-03-22

707 Substrate channeling in oxylipin biosynthesis through a protein complex in the plastid envelope of Arabidopsis thaliana

Pollmann, S.; Springer, A.; Rustgi, S.; von Wettstein, D.; Kang, C.; Reinbothe, C.; Reinbothe, S.

10.1101/286864 — cell biology — Posted on 2018-03-22

708 Object-vector coding in the medial entorhinal cortex

Hoydal, O. A.; Skytoen, E. R.; Moser, M.-B.; Moser, E. I.

10.1101/286286 — neuroscience — Posted on 2018-03-22

709 Murine SEC24D Can Substitute Functionally for SEC24C in vivo

Adams, E. J. J.; Khoriaty, R.; Kiseleva, A.; Cleuren, A. C. A.; Tomberg, K.; van der Ent, M. A.; Gergics, P.; O Shea, K. S.; Saunders, T. L.; Ginsburg, D.

10.1101/284398 — cell biology — Posted on 2018-03-22

710 Label-free assessment of pre-implantation embryo quality by the Fluorescence Lifetime Imaging Microscopy (FLIM)-phasor approach

Ma, N.; Reyes de Mochel, N.; Pham, P.; Yoo, T.; Cho, K.; Digman, M.

10.1101/286682 — developmental biology — Posted on 2018-03-22

711 Optical Imaging of Metabolic Dynamics in Animals

Shi, L.; Zheng, C.; Shen, Y.; Chen, Z.; Silveira, E. S.; Zhang, L.; Wei, M.; Liu, C.; de Sena-Tomas, C.; Targoff, K.; Min, W.

10.1101/285908 — biophysics — Posted on 2018-03-22

712 Conservation and divergence in modules of the transcriptional programs of the human and mouse immune systems

Shay, T.; Jojic, V.; Zuk, O.; Benoist, C.; Koller, D.; Regev, A.; ImmGen Consortium,

10.1101/286211 — bioinformatics — Posted on 2018-03-22

713 Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein MDM2

liu, j.; zou, x.; Gotoh, T.; Brown, A. M.; jiang, l.; Kim, J. K.; Finkielstein, C. v.

10.1101/286708 — molecular biology — Posted on 2018-03-21

714 Qoala-T: A supervised-learning tool for quality control of automatic segmented MRI data

Klapwijk, E. T.; van de Kamp, F.; van der Meulen, M.; Peters, S.; Wierenga, L. M.

10.1101/278358 — neuroscience — Posted on 2018-03-21

715 Single-molecule optical mapping enables accurate molecular diagnosis of facioscapulohumeral muscular dystrophy (FSHD)

Dai, Y.; Li, P.; Wang, Z.; Liang, F.; Yang, F.; Fang, L.; Huang, Y.; Huang, S.; Zhou, J.; Wang, D.; Cui, L.; Wang, K.

10.1101/286104 — genomics — Posted on 2018-03-21

716 Cost-effectiveness of telephone-based weight loss support for patients with knee osteoarthritis: a pragmatic randomised controlled trial

O'Brien, K. M.; van Dongen, J. M.; Williams, A.; Kamper, S. J.; Wiggers, J.; Hodder, R. K.; Campbell, E.; Robson, E. K.; Haskins, R.; Rissel, C.; Williams, C. M.

10.1101/284588 — clinical trials — Posted on 2018-03-21

717 Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects

Nguyen, P. A.; Deaton, A. M.; Nioi, P.; Ward, L. D.

10.1101/285858 — genetics — Posted on 2018-03-21

718 Structure of the human lipid-sensitive cation channel TRPC3

Fan, C.; Choi, W.; Du, J.; Lu, W.

10.1101/286153 — biophysics — Posted on 2018-03-21

719 Linear motor driven-rotary motion of a membrane-permeabilized ghost in Mycoplasma mobile

Kinosita, Y.; Miyata, M.; Nishizaka, T.

10.1101/286278 — biophysics — Posted on 2018-03-21

720 Frequent Monitoring of C-peptide Levels in Newly Diagnosed Type 1 Subjects Using Dried Blood Spots Collected at Home

Willemsen, R. H.; Burling, K.; Barker, P.; Ackland, F.; Dias, R. P.; Edge, J.; Smith, A.; Todd, J.; Lopez, B.; Mander, A. P.; Guy, C.; Dunger, D. B.

10.1101/286237 — biochemistry — Posted on 2018-03-21

721 A specific, glycomimetic Langerin ligand for human Langerhans cell targeting

10.1101/286021 — immunology — Posted on 2018-03-21

722 MUTE Directly Orchestrates Cell State Switch and the Single Symmetric Division to Create Stomata

Han, S.-K.; Qi, X.; Sugihara, K.; Dang, J.; Endo, T. A.; Miller, K.; Kim, E.-D.; Miura, T.; Torii, K.

10.1101/286443 — plant biology — Posted on 2018-03-21

723 Distinct Functional Connectivity Mode during Viewing Natural Scenes Revealed by Principal Component Analysis

Demirtas, M.; Ponce-Alvarez, A.; Gilson, M.; Hagmann, P.; Mantini, D.; Betti, V.; Romani, G. L.; Friston, K.; Corbetta, M.; Deco, G.

10.1101/286484 — neuroscience — Posted on 2018-03-21

724 Of Rats And Men: Peer Presence And Familiarity Are Key Factors Which Modulate Drug Intake

Giorla, E.; Nordmann, S.; Pelloux, Y.; Roux, P.; Rosellini, S.; Davranche, K.; Vilotitch, A.; Huguet, P.; Carrieri, P.; Baunez, C.

10.1101/286518 — neuroscience — Posted on 2018-03-21

725 Open Force Field Consortium: Escaping atom types using direct chemical perception with SMIRNOFF v0.1

Mobley, D.; Bannan, C. C.; Rizzi, A.; Bayly, C. I.; Chodera, J. D.; Lim, V. T.; Lim, N. M.; Beauchamp, K. A.; Shirts, M. R.; Gilson, M. K.; Eastman, P. K.

10.1101/286542 — biophysics — Posted on 2018-03-21

726 Phosphoserine acidic cluster motifs in the cytoplasmic domains of transmembrane proteins bind distinct basic regions on the μ subunits of clathrin adaptor protein complexes

Singh, R.; Stoneham, C.; Lim, C.; jia, X.; Guenaga, J.; Wyatt, R.; Wertheim, J. o.; Xiong, Y.; Guatelli, J.

10.1101/286633 — biochemistry — Posted on 2018-03-21

727 Aversive conditioning in oddball paradigm modulates multisensory integration, attention and emotional processing

Pavlov, Y. G.; Kotchoubey, B.

10.1101/286492 — neuroscience — Posted on 2018-03-21

728 Click-xylosides overcome neurotoxic effects of reactive astrocytes and promote neuronal growth in a cell culture model of brain injury

Swarup, V.; Balagurunathan, K.

10.1101/286450 — neuroscience — Posted on 2018-03-21

729 Unmodified, autologous adipose-derived regenerative cells improve cardiac function, structure and revascularization in a porcine model of chronic myocardial infarction

Haenel, A.; Ghosn, M.; Karimi, T.; Vykoukal, J.; Kettlun, C.; Shah, D.; Dave, A.; Valderrabano, M.; Schulz, D.; Azares, A.; Raizner, A.; Alt, E.

10.1101/286468 — molecular biology — Posted on 2018-03-21

730 A comprehensive automated pipeline for human microbiome sampling, 16S rRNA gene sequencing and bioinformatics processing

Hugerth, L. W.; Seifert, M.; Pennhag, A. A. L.; Du, J.; Hamsten, M. C.; Schuppe-Koistinen, I.; Engstrand, L.

10.1101/286526 — microbiology — Posted on 2018-03-21

731 Machine learning reveals missing edges and putative interaction mechanisms in microbial ecosystem networks

DiMucci, D.; Kon, M.; Segre, D.

10.1101/286641 — bioinformatics — Posted on 2018-03-21

732 Integrative cross-species analyses identify deficits in habituation learning as a widely affected mechanism in Autism

Fenckova, M.; Asztalos, L.; Cizek, P.; Singgih, E. L.; Blok, L. E. R.; Glennon, J. C.; IntHout, J.; Zweier, C.; Eichler, E. E.; Bernier, R.; Asztalos, Z.; Schenck, A.

10.1101/285981 — neuroscience — Posted on 2018-03-21

733 RppH can faithfully replace TAP to allow cloning of 5’-triphosphate carrying small RNAs

Vasconcelos Almeida, M. V.; de Jesus Domingues, A. M.; Lukas, H.; Mendez-Lago, M.; Ketting, R. F.

10.1101/283077 — molecular biology — Posted on 2018-03-21

734 High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions

Aprianto, R.; Slager, J.; Holsappel, S.; Veening, J.-W.

10.1101/283739 — microbiology — Posted on 2018-03-21

735 The Transcriptional landscape of Streptococcus pneumoniae reveals a complex operon architecture and abundant riboregulation critical for growth and virulence

Warrier, I.; Ram-Mohan, N.; Zhu, Z.; Hazery, A.; Meyer, M. M.; van Opijnen, T.

10.1101/286344 — microbiology — Posted on 2018-03-21

736 High throughput characterization of genetic effects on DNA:protein binding and gene transcription

Kalita, C. A.; Brown, C. D.; Freiman, A.; Isherwood, J.; Wen, X.; Pique-Regi, R.; Luca, F.

10.1101/270991 — genetics — Posted on 2018-03-21

737 Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39

Slager, J.; Aprianto, R.; Veening, J.-W.

10.1101/283663 — microbiology — Posted on 2018-03-21

738 Profiling of pluripotency factors in individual stem cells and early embryos

Hainer, S. J.; Boskovic, A.; Rando, O. J.; Fazzio, T. G.

10.1101/286351 — genomics — Posted on 2018-03-21

739 Sex-specific changes in the aphid DNA methylation landscape

Mathers, T. C.; Mugford, S. T.; Percival-Alwyn, L.; Chen, Y.; Kaithakottil, G.; Swarbreck, D.; Hogenhout, S. A.; van Oosterhout, C.

10.1101/286302 — genomics — Posted on 2018-03-21

740 DNA-Encircled Lipid Bilayers

Iric, K.; Subramanian, M.; Oertel, J.; Agarwal, N. P.; Matthies, M.; Periole, X.; Sakmar, T. P.; Huber, T.; Fahmy, K.; Schmidt, T.-L.

10.1101/285957 — biophysics — Posted on 2018-03-21

741 Reducing fluctuations in species composition facilitates artificial selection of microbial community function

Xie, L.; Shou, W.

10.1101/264689 — evolutionary biology — Posted on 2018-03-21

742 Selection in parental species predicts hybrid evolution

Runemark, A.; Bailey, R. I.; Bache-Mathiesen, L.; Saetre, G.-P.

10.1101/283689 — evolutionary biology — Posted on 2018-03-21

743 Hyperexcitable phenotypes in iPSC-derived neurons from patients with 15q11-q13 duplication syndrome, a genetic form of autism

Fink, J. J.; Schreiner, J. D.; Bloom, J. E.; Baker, D. S.; Robinson, T. M.; Lieberman, R.; Loew, L. M.; Chamberlain, S. J.; Levine, E.

10.1101/286336 — neuroscience — Posted on 2018-03-21

744 Combining next-generation sequencing and mtDNA data to uncover cryptic lineages of Mexican highland frogs

Zarza, E.; Connors, E. M.; Maley, J. M.; Tsai, W. L. E.; Heimes, P.; Kaplan, M.; McCormack, J. E.

10.1101/153601 — evolutionary biology — Posted on 2018-03-21

745 Auxin is not asymmetrically distributed in initiating Arabidopsis leaves

Bhatia, N.; Heisler, M. G.

10.1101/284554 — developmental biology — Posted on 2018-03-21

746 Identification of cis elements for spatio-temporal control of DNA replication

Sima, J.; Chakraborty, A.; Dileep, V.; Michalski, M.; Rivera-Mulia, J. C.; Trevilla-Garcia, C.; Klein, K. N.; Bartlett, D.; Washburn, B. K.; Paulsen, M. T.; Vera, D.; Nora, E. P.; Kraft, K.; Mundlos, S.; Bruneau, B. G.; Ljungman, M.; Fraser, P.; Ay, F.; Gilbert, D. M.

10.1101/285650 — molecular biology — Posted on 2018-03-21

747 Dynamics of human protein kinases linked to drug selectivity

Kern, D.; Pitsawong, W.; Buosi, V.; Otten, R.; Agafonov, R. V.; Zorba, A.; Kern, N.; Kutter, S.; Kern, G.; Padua, R. A.; Meniche, X.

10.1101/286310 — cancer biology — Posted on 2018-03-21

748 Increased prefrontal activity with aging reflects nonspecific neural responses rather than compensation

Morcom, A. M.; Cambridge Centre for Ageing and Neuroscience (Cam-CAN), ; Henson, R. N.

10.1101/156935 — neuroscience — Posted on 2018-03-21

749 Why not record from every channel with a CMOS scanning probe?

Dimitriadis, G.; Neto, J. P.; Aarts, A.; Alexandru, A.; Ballini, M.; Battaglia, F.; Calcaterra, L.; David, F.; Fiath, R.; Frazao, J.; Geerts, J. P.; Gentet, L. J.; Helleputte, N. V.; Holzhammer, T.; Hoof, C. v.; Horvath, D.; Lopes, G.; Lopez, C. M.; Maris, E.; Marques-Smith, A.; Marton, G.; McNaughton, B. L.; Meszena, D.; Mitra, S.; Musa, S.; Neves, H.; Nogueira, J.; Orban, G. A.; Pothof, F.; Putzeys, J.; Raducanu, B.; Ruther, P.; Schroeder, T.; Singer, W.; Tiesinga, P.; Ulbert, I.; Wang, S.; Welkenhuysen, M.; Kampff, A. R.

10.1101/275818 — neuroscience — Posted on 2018-03-21

750 No changes in parieto-occipital alpha during neural phase locking to visual quasi-periodic theta-, alpha-, and beta-band stimulation

Keitel, C.; Benwell, C. S.; Thut, G.; Gross, J.

10.1101/219766 — neuroscience — Posted on 2018-03-21

751 Insights into Parkinson’s disease from computational models of the basal ganglia

Humphries, M.; Obeso, J.; Dreyer, J. K.

10.1101/260992 — neuroscience — Posted on 2018-03-21

752 Leishmania naiffi and Leishmania guyanensis reference genomes highlight genome structure and gene evolution in the Viannia subgenus

Coughlan, S.; Taylor, A. S.; Feane, E.; Sanders, M.; Schonian, G.; Cotton, J. A.; Downing, T.

10.1101/233148 — genomics — Posted on 2018-03-21

753 Crumble: reference free lossy compression of sequence quality values

Bonfield, J. K.; McCarthy, S. A.; Durbin, R. A.

10.1101/243030 — bioinformatics — Posted on 2018-03-21

754 Hidden partners: Using cross-docking calculations to predict binding sites for proteins with multiple interactions

Lagarde, N.; Carbone, A.; Sacquin-Mora, S.

10.1101/244913 — bioinformatics — Posted on 2018-03-21

755 A sub-movement time scale of human motor adaptation

Crevecoeur, F.; Thonnard, J.-L.; Lefevre, P.

10.1101/269134 — neuroscience — Posted on 2018-03-21

756 Imposing a curfew on the use of screen electronic devices improves sleep and daytime vigilance in adolescents.

Perrault, A. A.; Bayer, L.; Peuvrier, M.; Afyouni, A.; Ghisletta, P.; Brockmann, C.; Spiridon, M.; Hulo Vesely, S.; Perrig, S.; Schwartz, S.; Sterpenich, V.

10.1101/259309 — neuroscience — Posted on 2018-03-21

757 Individual repeatability and heritability of divorce in a wild population

Germain, R. R.; Wolak, M. E.; Reid, J. M.

10.1101/254151 — evolutionary biology — Posted on 2018-03-21

758 Extracellular Pax6 regulates tangential Cajal-Retzius cell migration in the developing mouse neocortex

Kaddour, H.; Coppola, E.; Di Nardo, A.; Wizenmann, A.; Volovitch, M.; Prochiantz, A.; Pierani, A.

10.1101/269480 — neuroscience — Posted on 2018-03-21

759 Synthetic standards combined with error and bias correction improves the accuracy and quantitative resolution of antibody repertoire sequencing in human naive and memory B cells

Friedensohn, S.; Lindner, J. M.; Cornacchione, V.; Iazeolla, M.; Miho, E.; Zingg, A.; Meng, S.; Traggiai, E.; Reddy, S. T.

10.1101/284810 — immunology — Posted on 2018-03-21

760 Impulsive choice in mice lacking paternal expression of Grb10 suggests intra-genomic conflict in behavior

Dent, C. L.; Humby, T.; Swaden Lewis, K.; Ward, A.; Fischer-Colbrie, R.; Wilkinson, L.; Wilkins, J.; Isles, A.

10.1101/281873 — genetics — Posted on 2018-03-21

761 Dynamics and interactions of highly resolved marine plankton via automated high frequency sampling

Needham, D. M.; Fichot, E. B.; Wang, E.; Berdjeb, L.; Cram, J. A.; Fichot, C. G.; Fuhrman, J. A.

10.1101/216978 — microbiology — Posted on 2018-03-21

762 A note on measuring natural selection on principal component scores

Chong, V. K.; Fung, H. F.; Stinchcombe, J. R.

10.1101/212258 — evolutionary biology — Posted on 2018-03-21

763 Acute physical exercise improves memory consolidation in humans via BDNF and endocannabinoid signaling

Marin Bosch, B.; Bringard, A.; Logrieco, M. G.; Lauer, E.; Imobersteg, N. M.; Ferretti, G.; Thomas, A.; Schwartz, S.; Igloi, K.

10.1101/211227 — neuroscience — Posted on 2018-03-21

764 Machine learning identifies signatures of host adaptation in the bacterial pathogen Salmonella enterica

Wheeler, N. E.; Gardner, P. P.; Barquist, L.

10.1101/204669 — genomics — Posted on 2018-03-21

765 Mortality Data Suggests that Men do age faster than women

Lenart, P.; Kuruczova, D.; Bienertova Vasku, J.

10.1101/179846 — physiology — Posted on 2018-03-21

766 Reverse-Correlation Analysis of the Mechanosensation Circuit and Behavior in C. elegans Reveals Temporal and Spatial Encoding

Porto, D. A.; Giblin, J.; Zhao, Y.; Lu, H.

10.1101/147363 — bioengineering — Posted on 2018-03-21

767 Non-cell autonomous Otx2 homeoprotein regulates visual cortex plasticity through Gadd45

Apulei, J.; Kim, N.; Testa, D.; Ribot, J.; Morizet, D.; Bernard, C.; Jourdren, L.; Blugeon, C.; Di Nardo, A. A.; Prochiantz, A.

10.1101/163071 — neuroscience — Posted on 2018-03-21

768 Finding decodable information that is read out in behaviour

Grootswagers, T.; Cichy, R. M.; Carlson, T.

10.1101/248583 — neuroscience — Posted on 2018-03-21

769 Cellulose biosynthesis inhibition reduces cell cycle activity in a nitrate reductase- and cytokinin-dependent manner

Gigli-Bisceglia, N.; Engelsdorf, T.; Strnad, M.; Vaahtera, L.; Jamoune, A.; Alipanah, L.; Novak, O.; Hejatko, J.; Hamann, T.

10.1101/286161 — plant biology — Posted on 2018-03-21

770 Retinal Ganglion Cell Axon Sorting at the Optic Chiasm Requires Dystroglycan

Clements, R.; Wright, K. M.

10.1101/286005 — neuroscience — Posted on 2018-03-21

771 Mutation of Ebola Virus Matrix Protein Cysteine Residues Increases Binding to Phosphatidylserine through Increased Flexibility of a Lipid Binding Loop

Johnson, K. A.; Bhattarai, N.; Budicini, M. R.; Shirey, C. M.; Baker, S. C. B.; Gerstman, B. S.; Chapagain, P. P.; Stahelin, R. V.

10.1101/286120 — microbiology — Posted on 2018-03-21

772 Influenza A virus superinfection potential is regulated by viral genomic heterogeneity

Sun, J.; Brooke, C. B.

10.1101/286070 — microbiology — Posted on 2018-03-21

773 Association of predicted deleterious single nucleotide polymorphisms with carcass traits in meat-type chickens

Trevisoli, P. A.; Moreira, G. C. M.; Boschiero, C.; Cesar, A. S. M.; Petrini, J.; Ledur, M. C.; Mourao, G. B.; Coutinho, L. L.

10.1101/285924 — genetics — Posted on 2018-03-21

774 A chemoproteomic portrait of the oncometabolite fumarate

10.1101/285759 — cancer biology — Posted on 2018-03-21

775 A direct glia-to-neuron natural transdifferentiation ensures nimble sensory-motor coordination of male mating behaviour

Molina-Garcia, L.; Cook, S. J.; Kim, B.; Bonnington, R.; Sammut, M.; O'Shea, J.; Elliott, D.; Hall, D. H.; Emmons, S.; Barrios, A.; Poole, R. J.

10.1101/285320 — neuroscience — Posted on 2018-03-21

776 Muscarinic receptors regulate auditory and prefrontal cortical communication during auditory processing

James, N. M.; Gritton, H. J.; Kopell, N.; Sen, K.; Han, X.

10.1101/285601 — neuroscience — Posted on 2018-03-21

777 Leveraging Existing 16S rRNA Gene Surveys to Identify Reproducible Biomarkers in Individuals with Colorectal Tumors

Sze, M. A.; Schloss, P. D.

10.1101/285486 — microbiology — Posted on 2018-03-21

778 Seasonal variation of fermentation rate in Saccharomyces spp. (Ascomycota)?

Tiefenbrunner, D.; Gangl, H.; Lopandic, K.; Tiefenbrunner, W.

10.1101/285312 — microbiology — Posted on 2018-03-21

779 Recovering signals of ghost archaic admixture in the genomes of present-day Africans

Durvasula, A.; Sankararaman, S.

10.1101/285734 — genomics — Posted on 2018-03-21

780 Systematic Optimization of Whole Plant Carbon Nitrogen Interaction (WACNI) to Support Crop Design for Greater Yield

Chang, T.; Zhu, X.

10.1101/286112 — systems biology — Posted on 2018-03-21

781 Enhancing Simulations With Intra-subject Variability for Improved Psychophysical Assessments

Rinderknecht, M. D.; Lambercy, O.; Gassert, R.

10.1101/285387 — neuroscience — Posted on 2018-03-21

782 Nuisance Effects and the Limitations of Nuisance Regression in Dynamic Functional Connectivity fMRI

Nalci, A.; Rao, B. D.; Liu, T. T.

10.1101/285239 — neuroscience — Posted on 2018-03-21

783 Orbitofrontal cortex, dorsolateral prefrontal cortex, and hippocampus represent the magnitude of event saliency

Jafarpour, A.; Griffin, S.; Lin, J. J.; Knight, R. T.

10.1101/285718 — neuroscience — Posted on 2018-03-21

784 Metabolic adaptations underlie epigenetic vulnerabilities in chemoresistant breast cancer.

Deblois, G.; Tonekaboni, S. A.; Kao, Y.; Tai, F.; Liu, X.; Ettayebi, I.; Grillo, G.; Guilhamon, P.; Ba-alawi, W.; Fedor, A.; Murison, A.; Cescon, D.; Arrowsmith, C.; DeCarvalho, D.; Park, M.; Haibe-Kains, B.; Locasale, J. W.; Lupien, M.

10.1101/286054 — genomics — Posted on 2018-03-21

785 A statistical framework for cross-tissue transcriptome-wide association analysis

Hu, Y.; Li, M.; Lu, Q.; Weng, H.; Wang, J.; Zekavat, S. M.; Yu, Z.; Li, B.; Muchnik, S.; Shi, Y.; Kunkle, B. W.; Mukherjee, S.; Natarajan, P.; Naj, A.; Kuzma, A.; Zhao, Y.; Crane, P. K.; Alzheimer's Disease Genetics Consortium, ; Zhao, H.

10.1101/286013 — genetics — Posted on 2018-03-21

786 A novel pollen-tracking method: using quantum dots as pollen labels

Minnaar, C.; Anderson, B.

10.1101/286047 — evolutionary biology — Posted on 2018-03-21

787 Error Correcting Optical Mapping Data

Mukherjee, K.; Washimkar, D.; Muggli, M. D.; Salmela, L.; Boucher, C.

10.1101/285692 — bioinformatics — Posted on 2018-03-21

788 Microdeletions excluding YWHAE and PAFAH1B1 cause a unique leukoencephalopathy and hypermobility syndrome: Further delineation of the 17p13.3 microdeletion spectrum

Emrick, L. T.; Rosenfeld, J. A.; Lalani, S. R.; Jain, M.; Hunter, J. V.; Nagakura, H.; Immken, L. L.; Burrage, L. C.; Bacino, C. A.; Belmont, J. W.; Undiagnosed Diseases Network, ; Lee, B.

10.1101/286146 — genetics — Posted on 2018-03-21

789 A proteome-based design of bitter peptide digestion regime to attenuate cod-bone soup bitterness: comparison with a rainbow trout extract-mediated bitter taste masking approach

Han, Y.; Guo, C.; Yan, Z.; Jin, F.; Jiang, J.; Zhang, Z.

10.1101/279265 — biochemistry — Posted on 2018-03-21

790 Pardon the interruption: saccadic inhibition enables the rapid deployment of alternate oculomotor plans

Salinas, E.; Stanford, T. R.

10.1101/285841 — neuroscience — Posted on 2018-03-21

791 Three dimensional two-photon imaging of neuronal activity in freely moving mice using a miniature fiber coupled microscope with active axial-scanning

Ozbay, B. N.; Futia, G. L.; Ma, M.; Bright, V. M.; Gopinath, J. T.; Hughes, E. G.; Restrepo, D.; Gibson, E. A.

10.1101/226431 — neuroscience — Posted on 2018-03-20

792 Higher-order thalamocortical inputs gate synaptic long-term potentiation via disinhibiton

Williams, L. E.; Holtmaat, A.

10.1101/281477 — neuroscience — Posted on 2018-03-20

793 Ipsilateral finger representations are engaged in active movement, but not sensory processing

Berlot, E.; Prichard, G.; O'Reilly, J.; Ejaz, N.; Diedrichsen, J.

10.1101/285809 — neuroscience — Posted on 2018-03-20

794 Integrative cross-species analyses identify deficits in habituation learning as a widely affected mechanism in Autism

Fenckova, M.; Asztalos, L.; Cizek, P.; Singgih, E. L.; Blok, L. E. R.; Glennon, J. C.; IntHout, J.; Zweier, C.; Eichler, E. E.; Bernier, R.; Asztalos, Z.; Schenck, A.

10.1101/285981 — neuroscience — Posted on 2018-03-20

795 The Genomic Prediction of Disease: Example of type 2 diabetes (T2D)

Sirovich, L.

10.1101/285783 — genomics — Posted on 2018-03-20

796 The draft genome of the invasive walking stick, Medauroidea extradendata, reveals extensive lineage-specific gene family expansions of cell wall degrading enzymes in Phasmatodea

Brand, P.; Lin, W.; Johnson, B. R.

10.1101/285817 — genomics — Posted on 2018-03-20

797 Inferring Disease Risk Genes from Sequencing Data in Multiplex Pedigrees Through Sharing of Rare Variants

Bureau, A.; Begum, F.; Taub, M. A.; Hetmanski, J.; Parker, M. M.; Albacha-Hejazi, H.; Scott, A. F.; Murray, J. C.; Marazita, M. L.; Bailey-Wilson, J. E.; Beaty, T. H.; Ruczinski, I.

10.1101/285874 — genetics — Posted on 2018-03-20

798 A barcoding approach to phylogenetic classification of Aedini mosquitoes (Aedes, Ochlerotatus)

Glass, H.; Carroll, E.; Curley, D.; Kienzle, H.; Yee, D. A.; Vamosi, S.

10.1101/285825 — evolutionary biology — Posted on 2018-03-20

799 Quantitative variation in female sensory structures supports species recognition and intraspecific mate choice functions in damselflies

Barnard, A. A.; Masly, J. P.

10.1101/285833 — evolutionary biology — Posted on 2018-03-20

800 MechRNA: prediction of lncRNA mechanisms from RNA-RNA and RNA-protein interactions

Gawronski, A. R.; Uhl, M.; Zhang, Y.; Lin, Y.-Y.; Niknafs, Y.; Ramnarine, V.; Malik, R.; Feng, F.; Chinnaiyan, A.; Collins, C.; Sahinalp, C.; Backofen, R.

10.1101/285965 — bioinformatics — Posted on 2018-03-20

801 Lateral plasma membrane compartmentalization links protein function and turnover

Wedlich-Soldner, R.; Busto, J. V.; Elting, A.; Haase, D.; Spira, F.; Schäfer-Herte, M.; Kuhlman, J.

10.1101/285510 — cell biology — Posted on 2018-03-20

802 Multi-Experiment Nonlinear Mixed Effect Modeling of Single-Cell Translation Kinetics after Transfection

Froehlich, F.; Reiser, A.; Fink, L.; Woschee, D.; Ligon, T.; Theis, F.; Raedler, J.; Hasenauer, J.

10.1101/285478 — systems biology — Posted on 2018-03-20

803 Increased H. pylori stool shedding and EPIYA-D cagA alleles are associated with gastric cancer in an East Asian hospital

Talarico, S.; Leverich, C.; Wei, B.; Ma, J.; Cao, X.; Guo, Y.; Han, G.; Yao, L.; Self, S.; Zhao, Y.; Salama, N. R.

10.1101/284448 — microbiology — Posted on 2018-03-20

804 Marionette: E. coli containing 12 highly-optimized small molecule sensors

Meyer, A. J.; Segall-Shapiro, T. H.; Voigt, C. A.

10.1101/285866 — synthetic biology — Posted on 2018-03-20

805 Acetylation-Dependent Recruitment of the FACT Complex and Its Role in Regulating Pol II Occupancy Genome-Wide in Saccharomyces cerevisiae.

Pathak, R.; Singh, P.; Ananthakrishnan, S.; Adamczyk, S.; Schimmel, O.; Govind, C. K.

10.1101/285932 — genetics — Posted on 2018-03-20

806 Genome wide association analysis identifies genetic variants associated with reproductive variation across domestic dog breeds and uncovers links to domestication

Phillips, J. B.; Smith, S. A.; Johnson, M. L.; Abbot, P.; Capra, J. A.; Rokas, A.

10.1101/285791 — evolutionary biology — Posted on 2018-03-20

807 Down-regulated Long Noncoding RNA HOXA11-AS affects trophoblast cell proliferation and migration by regulating RND3 and HOXA7 expression in preeclampsia

Sun, L.; Xu, Y.; Wu, D.; Liu, J.; Ma, Z.; Hui, B.; Wang, J.; Chen, Y.; Wang, S.; Lian, Y.

10.1101/285643 — molecular biology — Posted on 2018-03-20

808 CREAM: Clustering of genomic REgions Analysis Method

Madani Tonekaboni, S. A.; Mazrooei, P.; Kofia, V.; Haibe-Kains, B.; Lupien, M.

10.1101/222562 — bioinformatics — Posted on 2018-03-20

809 Improvement of Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms in School-Aged Children, Adolescents, and Young Adults With Autism via a Digital Smartglasses-Based Socioemotional Coaching Aid: An Efficacy Study

Vahabzadeh, A.; Keshav, N. U.; Salisbury, J. P.; Sahin, N. T.

10.1101/165514 — neuroscience — Posted on 2018-03-20

810 Word and sentence embedding tools to measure semantic similarity of Gene Ontology terms by their definitions

Duong, D.; Ahmad, W. U.; Eskin, E.; Chang, K.-W.; Li, J. J.

10.1101/103648 — bioinformatics — Posted on 2018-03-20

811 FUN-LOV: Fungal LOV domains for optogenetic control of gene expression and flocculation in yeast

Salinas, F.; Rojas, V.; Delgado, V.; Lopez, J.; Agosin, E.; Larrondo, L. F.

10.1101/285296 — microbiology — Posted on 2018-03-20

812 Footprints of antigen processing boost MHC class II natural ligand binding predictions

Barra, C. M.; Alvarez, B.; Andreatta, M.; Buus, S.; Nielsen, M.

10.1101/285767 — immunology — Posted on 2018-03-20

813 Immuno-genomic PanCancer Landscape Reveals Diverse Immune Escape Mechanisms and Immuno-Editing Histories

Mizuno, S.; Yamaguchi, R.; Hasegawa, T.; Hayashi, S.; Fujita, M.; Zhang, F.; Koh, Y.; Lee, S.-Y.; Yoon, S.-S.; Shimizu, E.; Komura, M.; Fujimoto, A.; Nagai, M.; Kato, M.; Liang, H.; Miyano, S.; Zhang, Z.; Nakagawa, H.; Imoto, S.

10.1101/285338 — genomics — Posted on 2018-03-20

814 Novel susceptibility loci and genetic regulation mechanisms for type 2 diabetes

Xue, A.; Wu, Y.; Zhu, Z.; Zhang, F.; Kemper, K. E.; Zheng, Z.; Yengo, L.; Lloyd-Jones, L. R.; Sidorenko, J.; Wu, Y.; eQTLGen Consortium, ; McRae, A. F.; Visscher, P. M.; Zeng, J.; Yang, J.

10.1101/284570 — genetics — Posted on 2018-03-20

815 Inexpensive, scalable camera system for tracking rats in large spaces

Saxena, R.; Barde, W.; Deshmukh, S. S.

10.1101/285460 — neuroscience — Posted on 2018-03-20

816 Exploring the Impact of Analysis Software on Task fMRI Results

Bowring, A.; Maumet, C.; Nichols, T.

10.1101/285585 — neuroscience — Posted on 2018-03-20

817 Hierarchy, Morphology, and Adaptive Radiation: a Test of Osborn’s Law in the Carnivora

Slater, G. J.; Friscia, A. R.

10.1101/285700 — evolutionary biology — Posted on 2018-03-20

818 Lack of functional caveolae in Cav3 mutated human dystrophic myotubes results in deficient mechanoprotection and IL6/STAT3 mechanosignaling.

Dewulf, M.; Koester, D.; Sinha, B.; Viaris de Lesegno, C.; Chambon, V.; Bigot, A.; Tardif, N.; Johannes, L.; Nassoy, P.; Butler-Browne, G.; Lamaze, C.; Blouin, C. M.

10.1101/281113 — cell biology — Posted on 2018-03-20

819 Plk1 overexpression suppresses tumor development by inducing chromosomal instability

de Carcer, G.; Venkateswaran, S. V.; Salgueiro, L.; El Bakkali, A.; Somogyi, K.; Rowald, K.; Montanes, P.; Sanclemente, M.; Escobar, B.; de Martino, A.; McGranahan, N.; Malumbres, M.; Sotillo, R.

10.1101/285635 — cancer biology — Posted on 2018-03-20

820 Social intelligence model with multiple internal models

Isomura, T.; Parr, T.; Friston, K.

10.1101/285353 — neuroscience — Posted on 2018-03-20

821 Small effect size leads to reproducibility failure in resting-state fMRI studies

Jia, X.-Z.; Zhao, N.; Barton, B.; Burciu, R.; Carriere, N.; Cerasa, A.; Chen, B.-Y.; Chen, J.; Coombes, S.; Defebvre, L.; Delmaire, C.; Dujardin, K.; Esposito, F.; Fan, G.-G.; Federica, D. N.; Feng, Y.-X.; Fling, B. W.; Garg, S.; Gilat, M.; Gorges, M.; Ho, S.-L.; Horak, F. B.; Hu, X.; Hu, X.-F.; Huang, B.; Huang, P.-Y.; Jia, Z.-J.; Jones, C.; Kassubek, J.; Krajcovicova, L.; Kurani, A.; Li, J.; Li, Q.; Liu, A.-P.; Liu, B.; Liu, H.; Liu, W.-G.; Lopes, R.; Lou, Y.-T.; Luo, W.; Madhyastha, T.; Mao, N.-N.; McAlonan, G.; McKeown, M. J.; Pang, S. Y.; Quattrone, A.; Rektorova, I.; Sarica, A.; Shang, H

10.1101/285171 — neuroscience — Posted on 2018-03-20

822 Eco-evolutionary community turnover following environmental change

Lasky, J. R.

10.1101/285288 — evolutionary biology — Posted on 2018-03-20

823 Lipid perturbation-activated IRE-1 modulates autophagy and lipolysis during endoplasmic reticulum stress

Koh, J. H.; Wang, L.; Beaudoin-Chabot, C.; Thibault, G.

10.1101/285379 — cell biology — Posted on 2018-03-20

824 Metabolic modeling of Pectobacterium parmentieri SCC3193 provides insights into metabolic pathways of plant pathogenic bacteria

Zoledowska, S.; Presta, L.; Fondi, M.; Decorosi, F.; Giovannetti, L.; Mengoni, A.; Lojkowska, E.

10.1101/284968 — systems biology — Posted on 2018-03-20

825 Prestimulus neural alpha power predicts confidence in discriminating identical tones

Woestmann, M.; Waschke, L.; Obleser, J.

10.1101/285577 — neuroscience — Posted on 2018-03-20

826 Large-scale gene losses underlie the genome evolution of parasitic plant Cuscuta australis

Sun, G.; Xu, Y.; Liu, H.; Sun, T.; Zhang, J.; Hettenhausen, C.; Shen, G.; Qi, J.; Qin, Y.; Li, J.; Wang, L.; Chang, W.; Guo, Z.; Baldwin, I. T.; Wu, J.

10.1101/285593 — genomics — Posted on 2018-03-20

827 Roles of Vitamin Metabolizing Genes in Multidrug-Resistant Plasmids of Superbugs

Chakraborty, A. K.

10.1101/285403 — bioinformatics — Posted on 2018-03-20

828 Models that learn how humans learn: the case of depression and bipolar disorders

Dezfouli, A.; Griffiths, K.; Ramos, F.; Dayan, P.; Balleine, B. W.

10.1101/285221 — bioinformatics — Posted on 2018-03-20

829 A genetic link between whole-plant water use efficiency and leaf carbon isotope composition in the C4 grass Setaria

Ellsworth, P.; Feldman, M.; Baxter, I.; Cousins, A.

10.1101/285676 — plant biology — Posted on 2018-03-20

830 Productivity definition of the chilling requirement reveals underestimation of the impact of climate change on winter chill accumulation

Campoy, J. A.; Darbyshire, R.; Dirlewanger, E.; Quero-Garcia, J.; Wenden, B.

10.1101/285361 — plant biology — Posted on 2018-03-20

831 Laminar signal extraction over extended cortical areas by means of a spatial GLM

van Mourik, T.; van der Eerden, J. P.; Bazin, P.-L.; Norris, D. G.

10.1101/285544 — neuroscience — Posted on 2018-03-20

832 Germ layer specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm.

Salinas-Saavedra, M.; Rock, A. Q.; Martindale, M. Q.

10.1101/235267 — developmental biology — Posted on 2018-03-20

833 Identifying the genetic basis of variation in cell behaviour in human iPS cell lines from healthy donors

Vigilante, A.; Laddach, A.; Moens, N.; Meleckyte, R.; Leha, A.; Ghahramani, A.; Culley, O. J.; Kathuria, A.; Hurling, C.; Vickers, A.; Tewary, M.; Zandstra, P.; HipSci Consortium, ; Durbin, R.; Fraternali, F.; Stegle, O.; Birney, E.; Luscombe, N. M.; Danovi, D.; Watt, F. M.

10.1101/285627 — cell biology — Posted on 2018-03-20

834 Open-pFind enables precise, comprehensive and rapid peptide identification in shotgun proteomics

Chi, H.; Liu, C.; Yang, H.; Zeng, W.-F.; Wu, L.; Zhou, W.-J.; Niu, X.-N.; Ding, Y.-H.; Zhang, Y.; Wang, R.-M.; Wang, Z.-W.; Chen, Z.-L.; Sun, R.-X.; Liu, T.; Tan, G.-M.; Dong, M.-Q.; Xu, P.; Zhang, P.-H.; He, S.-M.

10.1101/285395 — bioinformatics — Posted on 2018-03-20

835 Structured priors in human forecasting

Quiroga, F.; Schulz, E.; Speekenbrink, M.; Harvey, N.

10.1101/285668 — animal behavior and cognition — Posted on 2018-03-20

836 A tutorial on how (not) to over-interpret STRUCTURE/ADMIXTURE bar plots

Lawson, D.; van Dorp, L.; Falush, D.

10.1101/066431 — genetics — Posted on 2018-03-20

837 Structural transition and antibody binding of Ebola GP and Zika E proteins from pre-fusion to fusion-initiation state

Lappala, A.; Nishima, W.; Miner, J.; Fenimore, P.; Fischer, W.; Hraber, P.; Zhang, M.; McMahon, B.; Tung, C.-S.

10.1101/285130 — biophysics — Posted on 2018-03-20

838 DIABLO: from multi-omics assays to biomarker discovery, an integrative approach

Singh, A.; Gautier, B.; Shannon, C. P.; Rohart, F.; Vacher, M.; Tebutt, S. J.; Le Cao, K.-A.

10.1101/067611 — bioinformatics — Posted on 2018-03-20

839 A High-Throughput Pipeline Identifies Robust Connectomes But Troublesome Variability

Kiar, G.; Bridgeford, E.; Roncal, W. G.; Consortium for Reliability and Reproducibliity (CoRR), ; Chandrashekhar, V.; Mhembere, D.; Ryman, S.; Zuo, X.-N.; Marguiles, D. S.; Craddock, R. C.; Priebe, C. E.; Jung, R.; Calhoun, V.; Caffo, B.; Burns, R.; Milham, M. P.; Vogelstein, J.

10.1101/188706 — neuroscience — Posted on 2018-03-20

840 An ensemble code in medial prefrontal cortex links prior events to outcomes during learning

Maggi, S.; Peyrache, A.; Humphries, M.

10.1101/187948 — neuroscience — Posted on 2018-03-20

841 Longitudinal development of hippocampal subregions from childhood to adulthood

Tamnes, C. K.; Bos, M. G. N.; van de Kamp, F. C.; Peters, S.; Crone, E. A.

10.1101/186270 — neuroscience — Posted on 2018-03-20

842 Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

Waldron, F. M.; Stone, G. N.; Obbard, D. J.

10.1101/166488 — evolutionary biology — Posted on 2018-03-20

843 Gene regulatory network architecture in different developmental contexts influences the genetic basis of morphological evolution

Kittelmann, S.; Buffry, A. D.; Franke, F. A.; Almudi, I.; Yoth, M.; Sabaris, G.; Couso, J. P.; Nunes, M. D. S.; Frankel, N.; Gomez-Skarmeta, J. L.; Pueyo-Marques, J.; Arif, S.; McGregor, A. P.

10.1101/219337 — evolutionary biology — Posted on 2018-03-20

844 Fast and Accurate Genomic Analyses using Genome Graphs

Rakocevic, G.; Semenyuk, V.; Spencer, J.; Browning, J.; Johnson, I.; Arsenijevic, V.; Nadj, J.; Ghose, K.; Suciu, M. C.; Ji, S.-G.; Demir, G.; Li, L.; Toptas, B. C.; Dolgoborodov, A.; Pollex, B.; Spulber, I.; Glotova, I.; Komar, P.; Stachyra, A.; Li, Y.; Popovic, M.; Lee, W.-P.; Kallberg, M.; Jain, A.; Kural, D.

10.1101/194530 — bioinformatics — Posted on 2018-03-20

845 Fronto-limbic dysconnectivity leads to impaired brain network controllability in young people with bipolar disorder and those at high genetic risk

Jeganathan, J.; Perry, A.; Bassett, D. S.; Roberts, G.; Mitchell, P. B.; Breakspear, M.

10.1101/222216 — neuroscience — Posted on 2018-03-20

846 Transcriptome-wide interrogation of the functional intronome by spliceosome profiling

Chen, W.; Moore, J.; Ozadam, H.; Shulha, H. P.; Rhind, N.; Weng, Z.; Moore, M. J.

10.1101/226894 — genomics — Posted on 2018-03-20

847 Additive and interactive effects of spatial attention and expectation on perceptual decisions

Zuanazzi, A.; Noppeney, U.

10.1101/235218 — neuroscience — Posted on 2018-03-20

848 Graph theory approaches to functional network organization in brain disorders: A critique for a brave new small-world

Hallquist, M. N.; Hillary, F. G.

10.1101/243741 — neuroscience — Posted on 2018-03-20

849 Humidity as a non-pharmaceutical intervention for influenza A

Reiman, J. M.; Das, B.; Sindberg, G.; Urban, M. D.; Hammerlund, M.; Lee, H.; Spring, K. M.; Lyman-Gingerich, J.; Generous, A.; Koep, T.; Ewing, K.; Lilja, P.; Enders, F.; Ekker, S.; Huskins, W. C.; Fadel, H.; Pierret, C.

10.1101/273870 — microbiology — Posted on 2018-03-20

850 Oscillating bacterial expression states generate herd immunity to viral infection

Turkington, C. J. R.; Morozov, A.; Clokie, M. R. J.; Bayliss, C. D.

10.1101/244814 — microbiology — Posted on 2018-03-20

851 Local Protein Dynamics During Microvesicle Exocytosis in Neuroendocrine Cells

Somasundaram, A.; Taraska, J. W.

10.1101/245647 — cell biology — Posted on 2018-03-20

852 Allele frequency-free inference of close familial relationships from genotypes or low depth sequencing data

Waples, R. K.; Albrechtsen, A.; Moltke, I.

10.1101/260497 — genetics — Posted on 2018-03-20

853 Synthetic standards combined with error and bias correction improves the accuracy and quantitative resolution of antibody repertoire sequencing in human and naive memory B cells

Friedensohn, S.; Lindner, J. M.; Cornacchione, V.; Iazeolla, M.; Miho, E.; Zingg, A.; Meng, S.; Traggiai, E.; Reddy, S. T.

10.1101/284810 — immunology — Posted on 2018-03-20

854 Creating a universal SNP and small indel variant caller with deep neural networks

Poplin, R.; Chang, P.-C.; Alexander, D.; Schwartz, S.; Colthurst, T.; Ku, A.; Newburger, D.; Dijamco, J.; Nguyen, N.; Afshar, P. T.; Gross, S. S.; Dorfman, L.; McLean, C. Y.; DePristo, M. A.

10.1101/092890 — genomics — Posted on 2018-03-20

855 The universal genetic code, protein coding genes and genomes of all species were optimized for frameshift tolerance

Wang, X.; Dong, Q.; Chen, G.; Zhang, J.; Liu, Y.; Zhao, J.; Peng, H.; Wang, Y.; Cai, Y.; Wang, X.; Yang, C.; Lynch, M.

10.1101/067736 — genetics — Posted on 2018-03-20

856 Supervised machine learning reveals introgressed loci in the genomes of Drosophila simulans and D. sechellia

Schrider, D.; Ayroles, J.; Matute, D. R.; Kern, A. D.

10.1101/170670 — evolutionary biology — Posted on 2018-03-20

857 Measuring genetic differentiation from Pool-seq data

Hivert, V.; Leblois, R.; Petit, E. J.; Gautier, M.; Vitalis, R.

10.1101/282400 — evolutionary biology — Posted on 2018-03-20

858 Evidence for sex microchromosomes in a species with temperature-influenced sex determination (Crotaphytus collaris)

Wiggins, J.; Santoyo-Brito, E.; Scales, J.; Fox, S.

10.1101/270983 — ecology — Posted on 2018-03-20

859 NRG1 is required for the function of the TIR-NLR immune receptors Roq1 and RPP1 in Nicotiana benthamiana

Qi, T.; Schultink, A.; Pham, J.; Cho, M.-J.; Staskawicz, B. J.

10.1101/284471 — plant biology — Posted on 2018-03-20

860 Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

Ramachandran Iyer, E. P.; Punthambaker, S.; Liu, S.; Jindal, K.; Farrell, M.; Murn, J.; Ferrante, T.; Rudnicki, S.; Kohman, R. E.; Wassie, A. T.; Goodwin, D.; Chen, F.; Alon, S.; Sinha, A.; Milanova, D.; Aron, L.; Camplisson, C.; Skrynnyk, A.; Reginato, P. L.; Conway, N.; Aach, J.; Yankner, B.; Boyden, E. S.; Church, G. M.

10.1101/281121 — cell biology — Posted on 2018-03-20

861 Recapitulation of human germline coding variation in an ultra-mutated infant leukemia

Gout, A. M.; Kotecha, R. S.; Kaur, P.; Abad, A.; Foley, B.; Carter, K. W.; Cole, C. H.; Bond, C. S.; Kees, U. R.; Waithman, J.; Cruickshank, M. N.

10.1101/248690 — cancer biology — Posted on 2018-03-20

862 Mechanisms for European Bat Lyssavirus subtype 1 persistence in non-synanthropic bats: insights from a modeling study

Colombi, D.; Serra Cobo, J.; Metras, R.; Apolloni, A.; Poletto, C.; Lopez-Roig, M.; Bourhy, H.; Colizza, V.

10.1101/283564 — epidemiology — Posted on 2018-03-20

863 Characterisation of carried and invasive Neisseria meningitidis isolates in Shanghai, China from 1950 to 2016: implications for serogroup B vaccine implementation

Chen, M.; Rodrigues, C. M. C.; Harrison, O. B.; Zhang, C.; Tan, T.; Chen, J.; Zhang, X.; Chen, M.; Maiden, M. C. J.

10.1101/284133 — epidemiology — Posted on 2018-03-20

864 LncRNA OIP5-AS1 is overexpressed in undifferentiated oral tumors and integrated analysis identifies as a downstream effector of stemness-associated transcription factors.

Arunkumar, G.; Anand, S.; Raksha, P.; Dhamodharan, S.; Prasanna Srinivasa Rao, H.; Subbiah, S.; Murugan, A. K.; Munirajan, A. K.

10.1101/285270 — genomics — Posted on 2018-03-19

865 Emergent orientation selectivity from random networks in mouse visual cortex

Pattadkal, J.; Mato, G.; van Vreeswijk, C.; Priebe, N. J.; hansel, d.

10.1101/285197 — neuroscience — Posted on 2018-03-19

866 Evidence for sex microchromosomes in a species with temperature-influenced sex determination (Crotaphytus collaris)

Wiggins, J.; Santoyo-Brito, E.; Scales, J.; Fox, S.

10.1101/270983 — ecology — Posted on 2018-03-19

867 Finding reliable phenotypes and detecting artefacts among in vivo and in vitro assays to characterize the refractory transcriptional activator Sxy (TfoX) in Escherichia coli

Alshabib, E. Y.; Fitzgerald, S. F.; Chao, T.-C.; Cameron, R. C.; Redfield, R. J.; Sinha, S.; Cameron, A. D.

10.1101/284836 — microbiology — Posted on 2018-03-19

868 High dimensional analyses of cells dissociated from cryopreserved synovial tissue

Donlin, L. T.; Rao, D. A.; Wei, K.; Slowikowski, K.; McGeachy, M. J.; Turner, J. D.; Meednu, N.; Mizoguchi, F.; Gutierrez-Arcelus, M.; Lieb, D. J.; Keegan, J.; Muskat, K.; Hillman, J.; Rozo, C.; Ricker, E.; Eisenhaure, T. M.; Li, S.; Browne, E. P.; Chicoine, A.; Sutherby, D.; Noma, A.; Nusbaum, C.; Kelly, S.; Pernis, A. B.; Ivashkiv, L. B.; Goodman, S. M.; Robinson, W. H.; Utz, P. J.; Lederer, J. A.; Gravallese, E. M.; Boyce, B. F.; Hacohen, N.; Pitzalis, C.; Gregersen, P. K.; Firestein, G. S.; Raychaudhuri, S.; Moreland, L. W.; Holers, M.; Bykerk, V. P.; Filer, A.; Boyle, D. L.; Brenner, M. B

10.1101/284844 — immunology — Posted on 2018-03-19

869 Chromatin features constrain structural variation across evolutionary timescales

Fudenberg, G.; Pollard, K.

10.1101/285205 — genomics — Posted on 2018-03-19

870 Third-generation in situ hybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust

Choi, H. M. T.; Schwarzkopf, M.; Fornace, M. E.; Acharya, A.; Artavanis, G.; Stegmaier, J.; Cunha, A.; Pierce, N. A.

10.1101/285213 — developmental biology — Posted on 2018-03-19

871 Idiosyncratic choice bias in decision tasks naturally emerges from neuronal network dynamics

Lebovich, L.; Darshan, R.; Lavi, Y.; Hansel, D.; Loewenstein, Y.

10.1101/284877 — neuroscience — Posted on 2018-03-19

872 Acute Food Deprivation Rapidly Modifies Valence-Coding Microcircuits in the Amygdala

Calhoon, G. G.; Sutton, A. K.; Chang, C.-J.; Libster, A. M.; Glober, G. F.; Leveque, C. L.; Murphy, G. D.; Namburi, P.; Leppla, C. A.; Siciliano, C. A.; Wildes, C. P.; Kimchi, E. Y.; Beyeler, A.; Tye, K. M.

10.1101/285189 — neuroscience — Posted on 2018-03-19

873 Holocene DNA sequences -- a dream come true

Sanyal, A.; Larsson, J.; van Wirdhum, F.; Andren, T.; Moros, M.; Lonn, M.; Andren, E.

10.1101/285122 — evolutionary biology — Posted on 2018-03-19

874 The infection dynamics of vertically transmitted viruses in a two-population model

Strauss, J. F.; Chauvet, M.; Telschow, A.

10.1101/284380 — ecology — Posted on 2018-03-19

875 Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites

Dickinson, M. S.; Anderson, L. N.; Webb-Robertson, B.-J. M.; Hansen, J. R.; Smith, R. D.; Wright, A. T.; Hybiske, K.

10.1101/285106 — microbiology — Posted on 2018-03-19

876 Using biological control data to understand host-pathogen dynamics

Mihaljevic, J. R.; Polivka, K. M.; Mehmel, C. J.; Li, C.; Dukic, V.; Dwyer, G.

10.1101/285080 — ecology — Posted on 2018-03-19

877 A constitutively expressed antifungal peptide protects Tenebrio molitor during a natural infection by the entomopathogenic fungus Beauveria bassiana.

Maistrou, S.; Paris, V.; Jensen, A. B.; Rolff, J.; Meyling, N. V.; Zanchi, C.

10.1101/284778 — immunology — Posted on 2018-03-19

878 Bayesian model comparison for rare variant association studies of multiple phenotypes

DeBoever, C.; Aguirre, M.; Tanigawa, Y.; Spencer, C. C. A.; Poterba, T.; Bustamante, C. D.; Daly, M. J.; Pirinen, M.; Rivas, M. A.

10.1101/257162 — genetics — Posted on 2018-03-19

879 Ongoing, rational calibration of reward-driven perceptual biases

Fan, Y.; Gold, J. I.; Ding, L.

10.1101/242651 — neuroscience — Posted on 2018-03-19

880 Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau

Rousseaux, M. W.; Revelli, J.-P.; Vazquez-Velez, G. E.; Kim, J.-Y.; Craigen, E.; Gonzales, K.; Beckinghausen, J.; Zoghbi, H. Y.

10.1101/284984 — neuroscience — Posted on 2018-03-19

881 The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

Pillai, S.; Stone, J.; Nakamura, S.; Kiyoshima, T.; Daccache, J.; Yamauchi, M.; Yamamoto, H.; Saeki, T.; Moriyama, M.; Ohta, M.; Ishiguro, N.; Yuen, G. J.; Murphy, S. L.; Mahajan, V.; Mattoo, H.; Maehara, T.

10.1101/284737 — immunology — Posted on 2018-03-19

882 Heartfelt Face Perception via the Interoceptive Pathway - a MEG study

Kim, J.; Park, H.-d.; Kim, K. W.; Shin, D. W.; Lim, S.; Kwon, H.; Kim, M.-Y.; Kim, K.; Jeong, B.

10.1101/200980 — neuroscience — Posted on 2018-03-19

883 Mind the gaps - ignoring errors in long read assemblies critically affects protein prediction

Watson, M.

10.1101/285049 — genomics — Posted on 2018-03-19

884 Region Specific Central Arbor Morphologies of Nociceptive Afferents Develop Independently of Their Peripheral Target Innervation

Luo, W.; Olson, W.

10.1101/285098 — neuroscience — Posted on 2018-03-19

885 Rapid Paediatric Sequencing (RaPS): Comprehensive real-life workflow for rapid diagnosis of critically ill children

Boukhibar, L.; Clement, E.; Jones, W.; Drury, S.; Ocaka, L.; Gagunashvili, A.; Le Quesne Stabej, P.; Bacchelli, C.; Jani, N.; Rahman, S.; Jenkins, L.; Hurst, J.; Bitner-Glindzicz, M.; Peters, M.; Beales, P.; Williams, H. J.

10.1101/283697 — genomics — Posted on 2018-03-19

886 NRG1 is required for the function of the TIR-NLR immune receptors Roq1 and RPP1 in Nicotiana benthamiana

Qi, T.; Schultink, A.; Cho, M.-J.; Pham, J.; Staskawicz, B. J.

10.1101/284471 — plant biology — Posted on 2018-03-19

887 Phase-tuned neuronal firing encodes human contextual representations for navigational goals

Watrous, A. J.; Miller, J.; Qasim, S. E.; Fried, I.; Jacobs, J.

10.1101/202374 — neuroscience — Posted on 2018-03-19

888 Efficient genome editing of Magnetospirillum magneticum AMB-1 by CRISPR-Cas9 system for analyzing magnetotactic behavior

Chen, H.; Zhang, S.-D.; Chen, L.; Cai, Y.; Zhang, W.-J.; Song, T.; Wu, L.-F.

10.1101/284786 — microbiology — Posted on 2018-03-19

889 Integrating co-expression networks with GWAS to prioritize causal genes in maize

Schaefer, R. J.; Michno, J.-M.; Jeffers, J.; Hoekenga, O.; Dilkes, B.; Baxter, I.; Myers, C.

10.1101/221655 — systems biology — Posted on 2018-03-19

890 Compound signaling activates endogenous retroviruses by inducing enhancer and gene-neighborhood transcription

Azebi, S.; Batsche, E.; Michel, F.; Kornobis, E.; Muchardt, C.

10.1101/284695 — molecular biology — Posted on 2018-03-19

891 Peripatric speciation associated with genome expansion and female-biased sex ratios in the moss genus Ceratodon

Nieto-Lugilde, M.; Werner, O.; McDaniel, S. F.; Koutecky, P.; Kucera, J.; Rizk, S. M.; Ros, R. M.

10.1101/227280 — molecular biology — Posted on 2018-03-19

892 Allosteric receptor modulation of FFA2R turns natural agonists into potent activators of the superoxide generating neutrophil NADPH-oxidase

Martensson, J.; Holdfeldt, A.; Sundqvist, M.; Gabl, M.; Bjorkman, L.; Forsman, H.; Dahlgren, C.

10.1101/284935 — cell biology — Posted on 2018-03-19

893 Behavioral and biochemical effects of ethanol withdrawal in zebrafish

Chaves, S. N. S.; Felicio, G. R.; Costa, B. P. D.; Oliveira, W. E. A.; Lima, M. G.; Silva, D. H. S.; Maximino, C.

10.1101/201368 — pharmacology and toxicology — Posted on 2018-03-19

894 Antibiotic-induced cell chaining triggers pneumococcal competence by reshaping quorum sensing to autocrine signaling

Domenech, A.; Slager, J.; Veening, J.-W.

10.1101/284125 — microbiology — Posted on 2018-03-19

895 Single-cell RNA-seq reveals profibrotic macrophages in lung fibrosis

Aran, D.; Looney, A. P.; Liu, L.; Fong, V.; Hsu, A.; Wolters, P. J.; Abate, A.; Butte, A. J.; Bhattacharya, M.

10.1101/284604 — immunology — Posted on 2018-03-19

896 Synthetic standards combined with error and bias correction improves the accuracy and quantitative resolution of antibody repertoire sequencing in human and naive memory B cells

Friedensohn, S.; Lindner, J. M.; Cornacchione, V.; Iazeolla, M.; Miho, E.; Zingg, A.; Meng, S.; Traggiai, E.; Reddy, S. T.

10.1101/284810 — immunology — Posted on 2018-03-19

897 Establishment of signaling interactions with cellular resolution for every cell cycle of embryogenesis

Zhao, Z.; Chen, L.; Ho, V. W.; Wong, M.-K.; Huang, X.; Chan, L.-y.; Ng, K. H.; Ren, X.; Yan, H.

10.1101/285007 — cell biology — Posted on 2018-03-19

898 Multisensory expectations shape olfactory input to the brain

Czarnecki, L.; Moberly, A.; Fast, C.; Turkel, D.; McGann, J.

10.1101/283242 — animal behavior and cognition — Posted on 2018-03-19

899 Paracingulate sulcus morphology and hallucinations in clinical and non-clinical groups

Garrison, J.; Fernyhough, C.; McCarthy-Jones, S.; Simons, J.; Sommer, I. E.

10.1101/284752 — neuroscience — Posted on 2018-03-19

900 MACS - a new SPM toolbox for model assessment, comparison and selection

Soch, J.; Allefeld, C.

10.1101/194365 — neuroscience — Posted on 2018-03-19

901 Complement receptor 1 gene (CR1) intragenic duplication and risk of Alzheimer’s disease

Kucukkilic, E.; Brookes, K.; Barber, I.; Guetta-Baranes, T.; ARUK Consortium, ; Morgan, K.; Hollox, E.

10.1101/284711 — genetics — Posted on 2018-03-19

902 Semi-soft Clustering of Single Cell Data

Zhu, L.; Lei, J.; Devlin, B.; Roeder, K.

10.1101/285056 — genetics — Posted on 2018-03-19

903 Genome-specific histories of divergence and introgression between an allopolyploid unisexual salamander lineage and two sexual species

Denton, R.; Morales, A.; Gibbs, H. L.

10.1101/284950 — evolutionary biology — Posted on 2018-03-19

904 Effects of larval density on gene regulation in C. elegans during routine L1 synchronization

Rando, O. J.; Chan, I. L.; Conine, C.

10.1101/284927 — developmental biology — Posted on 2018-03-19

905 Heterogeneity of the Frequency Domain Patterns in Persistent Atrial Fibrillation

Iravanian, S.; Langberg, J. J.

10.1101/285031 — biophysics — Posted on 2018-03-19

906 Fast and Accurate Genomic Analyses using Genome Graphs

Rakocevic, G.; Semenyuk, V.; Spencer, J.; Browning, J.; Johnson, I.; Arsenijevic, V.; Nadj, J.; Ghose, K.; Suciu, M. C.; Ji, S.-G.; Demir, G.; Li, L.; Toptas, B. C.; Dolgoborodov, A.; Pollex, B.; Glotova, I.; Komar, P.; Stachyra, A.; Li, Y.; Popovic, M.; Lee, W.-P.; Kallberg, M.; Jain, A.; Kural, D.

10.1101/194530 — bioinformatics — Posted on 2018-03-19

907 High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

Mason, D. M.; Weber, C. R.; Parola, C.; Meng, S. M.; Greiff, V.; Kelton, W. J.; Reddy, S. T.

10.1101/285015 — bioengineering — Posted on 2018-03-19

908 Conversion of a soluble protein into a potent chaperone in vivo

Choi, S. I.; Kwon, S. B.; Ryu, K.; Son, A.; Jeong, H.; Lim, K.-H.; Kim, K.-H.; Seong, B.

10.1101/284802 — biochemistry — Posted on 2018-03-19

909 Patterns of thaumarchaeal gene expression in culture and diverse marine environments

Carini, P.; Dupont, C.; Santoro, A. E.

10.1101/175141 — microbiology — Posted on 2018-03-19

910 Growth arrest in the active rare biosphere

Hausmann, B.; Pelikan, C.; Rattei, T.; Loy, A.; Pester, M.

10.1101/284430 — microbiology — Posted on 2018-03-19

911 Premature termination codons signal targeted gene repair by nonsense mRNA-mediated gene editing in E. coli

Wang, X.; Peng, H.; Li, C.; Wang, X.; Wang, Y.; Chen, G.; Zhang, J.; Lynch, M.

10.1101/069971 — genetics — Posted on 2018-03-19

912 Avian keratin disorder of Alaska black-capped chickadees is associated with Poecivirus infection

Zylberberg, M.; Van Hemert, C.; Handel, C. M.; DeRisi, J.

10.1101/284992 — microbiology — Posted on 2018-03-19

913 Better estimation of SNP heritability from summary statistics provides a new understanding of the genetic architecture of complex traits

Speed, D.; Balding, D.

10.1101/284976 — genetics — Posted on 2018-03-19

914 Metannot: A succinct data structure for compression of colors in dynamic de Bruijn graphs

Mustafa, H.; Kahles, A.; Karasikov, M.; Raetsch, G.

10.1101/236711 — bioinformatics — Posted on 2018-03-19

915 Comparison of video-based and sensor-based head impact exposure

Kuo, C.; Wu, L. C.; Loza, J.; Senif, D.; Anderson, S.; Camarillo, D. B.

10.1101/235432 — bioengineering — Posted on 2018-03-19

916 FGIN-1-27, an agonist at translocator protein 18 kDa (TSPO), produces anti-anxiety and anti-panic effects in non-mammalian models

Lima, M. G.; Cueto-Escobedo, J.; Rodriguez-Landa, J. F.; Maximino, C.

10.1101/056507 — pharmacology and toxicology — Posted on 2018-03-19

917 Long-read genome sequence and assembly of Leptopilina boulardi: a specialist Drosophila parasitoid

Khan, S.; Sowpati, D. T.; Mishra, R. K.

10.1101/284679 — genomics — Posted on 2018-03-19

918 Natural selection on plasticity of thermal traits in a highly seasonal environment

Bacigalupe, L. D.; Gaitan-Espitia, J. D.; Barria, A. M.; Gonzalez, A.; Ruiz-Aravena, M.; Trinder, M.; Sinervo, B.

10.1101/191825 — evolutionary biology — Posted on 2018-03-19

919 GLUE: A flexible software system for virus sequence data

Singer, J. B.; Thomson, E. C.; McLauchlan, J.; Hughes, J.; Gifford, R. J.

10.1101/269274 — bioinformatics — Posted on 2018-03-19

920 A molecular network for functional versatility of HECATE transcription factors

Gaillochet, C.; Jamge, S.; van der Wal, F.; Angenent, G.; Immink, R.; Lohmann, J. U.

10.1101/253815 — plant biology — Posted on 2018-03-19

921 Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice

Corty, R. W.; Kumar, V.; Tarantino, L.; Takahashi, J.; Valdar, W.

10.1101/276972 — genetics — Posted on 2018-03-19

922 Excitability regulation in the dorsomedial prefrontal cortex during sustained instructed fear responses: a TMS-EEG study

Gonzalez-Escamilla, G.; Chirumamilla, V. C.; Meyer, B.; Bonertz, T.; von Grothus, S.; Vogt, J.; Stroh, A.; Tuescher, O.; Kalisch, R.; Muthuraman, M.; Groppa, S.

10.1101/277806 — neuroscience — Posted on 2018-03-19

923 Elucidating the activation mechanisms for bifurcation of regulatory and effector T cell fates by multidimensional single cell analysis

Bradley, A.; Hashimoto, T.; Ono, M.

10.1101/280818 — immunology — Posted on 2018-03-19

924 Identify and predict environmental change effects on tiger mosquitos, Aedes polynesiensis

Grziwotz, F.; Strauss, J. F.; Hsieh, C.-h.; Telschow, A.

10.1101/284174 — ecology — Posted on 2018-03-19

925 Habits without Values

Miller, K.; Shenhav, A.; Ludvig, E.

10.1101/067603 — animal behavior and cognition — Posted on 2018-03-19

926 Cross-disorder analysis of schizophrenia and 19 immune diseases reveals genetic correlation

Pouget, J. G.; Schizophrenia Working Group of the PGC, ; Han, B.; Mignot, E.; Ollila, H. M.; Barker, J.; Spain, S.; Dand, N.; Trembath, R.; Martin, J.; Mayes, M. D.; Bossini-Castillo, L.; Lopez-Isac, E.; Jin, Y.; Santorico, S.; Spritz, R. A.; Raychaudhuri, S.; Knight, J.

10.1101/068684 — genetics — Posted on 2018-03-19

927 The universal genetic code, protein coding genes and genomes of all species were optimized for frameshift tolerance

Wang, X.; Dong, Q.; Chen, G.; Zhang, J.; Liu, Y.; Zhao, J.; Peng, H.; Wang, Y.; Cai, Y.; Wang, X.; Yang, C.

10.1101/067736 — genetics — Posted on 2018-03-19

928 Implementation of CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing

Jing, X.; Zhang, N.; Xie, B.; Chen, L.; Jiang, Y.; Qin, H.; Hao, P.; Yang, S.; Li, X.

10.1101/284661 — synthetic biology — Posted on 2018-03-19

929 Non-canonical Wnt signalling initiates scarring in biliary disease

Wilson, D. H.; Mellin, R. P.; Younger, N. T.; Jarman, E. J.; Raven, A.; Chen, P.; Dean, C.; Henderson, D.; Kendall, T.; Boulter, L.

10.1101/276196 — physiology — Posted on 2018-03-19

930 Human neuroblastoma SH-SY5Y cells treated with okadaic acid express phosphorylated high molecular weight tau immunoreactive protein species

Boban, M.; Miskic, T.; Babic Leko, M.; Hof, P. R.; Simic, G.

10.1101/284265 — neuroscience — Posted on 2018-03-19

931 Sensory Deprivation Independently Regulates Neocortical Feedforward and Feedback Excitation-Inhibition Ratio

Miska, N. J.; Richter, L. M.; Cary, B. A.; Gjorgjieva, J.; Turrigiano, G. G.

10.1101/283853 — neuroscience — Posted on 2018-03-19

932 6mer Seed Toxicity Determines Strand Selection in miRNAs

Gao, Q. Q.; Putzbach, W. E.; Murmann, A. E.; Chen, S.; Ambrosini, G.; Peter, J. M.; Bartom, E. T.; Peter, M.

10.1101/284406 — cell biology — Posted on 2018-03-19

933 Mechanistic description of spatial processes using integrative modelling of noise-corrupted imaging data

Hross, S.; Theis, F. J.; Sixt, M.; Hasenauer, J.

10.1101/284547 — systems biology — Posted on 2018-03-19

934 Diverse RNA interference strategies in early-branching metazoans

Calcino, A. D.; Fernandez-Valverde, S. L.; Taft, R. J.; Degnan, B. M.

10.1101/284349 — genomics — Posted on 2018-03-19

935 Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets via protocol-specific bias modeling

Karabacak Calviello, A.; Hirsekorn, A.; Wurmus, R.; Yusuf, D.; Ohler, U.

10.1101/284364 — genomics — Posted on 2018-03-19

936 BisPin and BFAST-Gap: Mapping Bisulfite-Treated Reads

Porter, J.; Zhang, L.

10.1101/284596 — bioinformatics — Posted on 2018-03-19

937 A probabilistic interpretation of PID controllers using active inference

Baltieri, M.; Buckley, C. L.

10.1101/284562 — systems biology — Posted on 2018-03-19

938 Assessment of the transmural unipolar electrogram morphology change radius during contact force-guided pulmonary vein isolation using the VISITAG™ Module and CARTOREPLAY™

Tomlinson, D. R.; Stevens, K. N.; Streeter, A. J.

10.1101/284539 — physiology — Posted on 2018-03-19

939 A Bayesian sequential learning framework to parameterise continuum models of melanoma invasion into human skin

Browning, A.; Haridas, P.; Simpson, M.

10.1101/284612 — biophysics — Posted on 2018-03-19

940 A benchmarking study on virtual ligand screening against homology models of human GPCRs

Lim, V. J. Y.; Du, W.; Chen, Y. Z.; Fan, H.

10.1101/284075 — bioinformatics — Posted on 2018-03-19

941 NRG1 is required for the function of the TIR-NLR immune receptors Roq1 and RPP1 in Nicotiana benthamiana

Staskawicz, B.; Qi, T.; Schultink, A.; Cho, M.-J.; Pham, J.

10.1101/284471 — plant biology — Posted on 2018-03-18

942 Acquisition and loss of secondary metabolite clusters shaped the evolutionary path of three recently emerged phytopathogens of wheat

Thynne, E.; Mead, O.; Chooi, Y.-H.; McDonald, M.; Solomon, P.

10.1101/283416 — plant biology — Posted on 2018-03-18

943 Thy1 transgenic mice expressing the red fluorescent calcium indicator jRGECO1a for neuronal population imaging in vivo

Dana, H.; Novak, O.; Guardado-Montesino, M.; Fransen, J. W.; Hu, A.; Borghuis, B. G.; Guo, C.; Kim, D. S.; Svoboda, K.

10.1101/284497 — neuroscience — Posted on 2018-03-18

944 The Evolution of Genetic Bandwagoning

Solon, I.

10.1101/064493 — evolutionary biology — Posted on 2018-03-18

945 Cyto-nuclear shuttling of afadin is required for rapid estradiol-mediated modifications of histone H3

Sellers, K. J.; Watson, I. A.; Srivastava, D. P.

10.1101/284422 — neuroscience — Posted on 2018-03-18

946 Cell-type heterogeneity in adipose tissue is associated with complex traits and reveals disease-relevant cell-specific eQTLs

Glastonbury, C. A.; Couto Alves, A.; El-Sayed Moustafa, J.; Small, K. S.

10.1101/283929 — genomics — Posted on 2018-03-18

947 Extensive horizontal exchange of transposable elements in the Drosophila pseudoobscura group

Hill, T.; Betancourt, A.

10.1101/284117 — genomics — Posted on 2018-03-18

948 A single spectrum of neuronal identities across thalamus

Phillips, J. W.; Schulmann, A.; Hara, E.; Liu, C.; Wang, L.; Shields, B.; Korff, W.; Lemire, A.; Dudman, J.; Nelson, S. B.; Hantman, A.

10.1101/241315 — neuroscience — Posted on 2018-03-18

949 Transposable elements and gene expression during the evolution of amniotes

Zeng, L.; Pederson, S.; Kortschak, D.; Adelson, D.

10.1101/283390 — evolutionary biology — Posted on 2018-03-18

950 A biological-computational human cell lineage discovery platform based on duplex molecular inversion probes

Tao, L.; Raz, O.; Marx, Z.; Biezuner, T.; Amir, S.; Milo, L.; Adar, R.; Onn, A.; Chapal-Ilani, N.; Berman, V.; Levy, R.; Oron, B.; Shapiro, E.

10.1101/191296 — systems biology — Posted on 2018-03-18

951 A low-level perceptual correlate of behavioral and clinical deficits in ADHD

Mihali, A.; Young, A. G.; Adler, L. A.; Halassa, M. M.; Ma, W. J.

10.1101/199216 — neuroscience — Posted on 2018-03-18

952 6mer Seed Toxicity Determines Strand Selection in miRNAs

Gao, Q. Q.; Putzbach, W. E.; Murmann, A. E.; Chen, S.; Ambrosini, G.; Peter, J. M.; Bartom, E. T.; Peter, M.

10.1101/284406 — cell biology — Posted on 2018-03-18

953 Structural view on the role of WT1’s zinc finger 1 in DNA binding

Yengo, R. K.; Nurmemmedov, E.; Thunnissen, M. M.

10.1101/284489 — biophysics — Posted on 2018-03-18

954 Biomolecular simulations under realistic macroscopic salt conditions

Ross, G. A.; Rustenburg, A. S.; Grinaway, P. B.; Fass, J.; Chodera, J. D.

10.1101/226001 — biophysics — Posted on 2018-03-18

955 N6-Methyladenine DNA Modification in Human Genome

Xiao, C.-L.; Zhu, S.; He, M.-H.; Chen, Y.; Yu, G.-L.; Chen, D.; Xie, S.-Q.; Luo, F.; Liang, Z.; Gu, X.-F.; Wang, K.; Yan, G.-R.

10.1101/176958 — genomics — Posted on 2018-03-18

956 Seeing spots: Measuring, quantifying heritability, and assessing fitness consequences of coat pattern traits in a wild population of giraffes (Giraffa camelopardalis)

Lee, D. E.; Cavener, D. R.; Bond, M. L.

10.1101/161281 — evolutionary biology — Posted on 2018-03-18

957 Neurodesign: Optimal experimental designs for task fMRI

Durnez, J.; Blair, R.; Poldrack, R.

10.1101/119594 — neuroscience — Posted on 2018-03-18

958 A statistical framework for mapping risk genes from de novo mutations in whole-genome sequencing studies

Liu, Y.; Liang, Y.; Cicek, A. E.; Li, Z.; Li, J.; Muhle, R. A.; Krenzer, M.; Mei, Y.; Wang, Y.; Knoblauch, N.; Morrison, J.; Zhao, S.; Jiang, Y.; Geller, E.; Ionita-Laza, I.; Wu, J.; Xia, K.; Noonan, J. P.; Sun, Z. S.; He, X.

10.1101/077578 — genetics — Posted on 2018-03-18

959 State-Unspecific Modes of Whole-Brain Functional Connectivity Predict Intelligence and Life Outcomes

Takagi, Y.; Hirayama, J.-i.; Tanaka, S. C.

10.1101/283846 — neuroscience — Posted on 2018-03-18

960 Mean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice

Corty, R. W.; Kumar, V.; Tarantino, L.; Takahashi, J.; Valdar, W.

10.1101/276972 — genetics — Posted on 2018-03-18

961 Scaffolding of RhoA contractile signaling by anillin: a regulatory analogue of kinetic proofreading

Budnar, S.; Husain, K. B.; Gomez, G. A.; Naghibosidat, M.; Verma, S.; Hamilton, N. A.; Morris, R. G.; Yap, A. S.

10.1101/282756 — cell biology — Posted on 2018-03-18

962 Transdiagnostic multimodal neuroimaging in psychosis: structural, resting-state, and task MRI correlates of cognitive control

Lerman-Sinkoff, D. B.; Kandala, S.; Calhoun, V. D.; Barch, D. M.; Mamah, D. T.

10.1101/284273 — neuroscience — Posted on 2018-03-18

963 Eye-movement intervention enhances extinction via amygdala deactivation

de Voogd, L. D.; Kanen, J. W.; Neville, D. A.; Roelofs, K.; Fernandez, G.; Hermans, E. J.

10.1101/282467 — neuroscience — Posted on 2018-03-18

964 HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells

Harrison, H.; Pegg, H. J.; Thompson, J.; Bates, C.; Shore, P.

10.1101/266213 — cancer biology — Posted on 2018-03-18

965 Structure of WT1 zinc fingers bound to its cognate DNA: Implications of the KTS insert

Yengo, R. K.; Nurmemmedov, E.; Thunnissen, M. M.

10.1101/271577 — biophysics — Posted on 2018-03-18

966 Dynamic Construction of Reduced Representations in the Brain for Perceptual Decision Behavior

Zhan, J.; Ince, R.; van Rijsbergen, N.; Schyns, P.

10.1101/284158 — neuroscience — Posted on 2018-03-18

967 Altered Bile Acid Profile in Mild Cognitive Impairment and Alzheimer’s Disease: Relationship to Neuroimaging and CSF Biomarkers

Nho, K.; Kueider-Paisley, A.; MahmoudianDehkord, S.; Arnold, M.; Risacher, S. L.; Louie, G.; Blach, C.; Baillie, R.; Han, X.; Kastenmueller, G.; Jia, W.; Xie, G.; Ahmad, S.; Hankemeier, T.; van Duijn, C. M.; Trojanowski, J. Q.; Shaw, L. M.; Weiner, M. W.; Doraiswamy, P. M.; Saykin, A. J.; Kaddurah-Daouk, R.; Alzheimers Disease Neuroimaging Initiative, ; Alzheimer Disease Metabolomics Consortium,

10.1101/284141 — neuroscience — Posted on 2018-03-18

968 External and Internally Generated Task Predictions are Integrated in Prefrontal Cortex to Jointly Guide Cognitive Control

Jiang, J.; Wagner, A. D.; Egner, T.

10.1101/284059 — neuroscience — Posted on 2018-03-18

969 Sensory Deprivation Independently Regulates Neocortical Feedforward and Feedback Excitation-Inhibition Ratio

Miska, N. J.; Richter, L. M.; Cary, B. A.; Gjorgjieva, J.; Turrigiano, G. G.

10.1101/283853 — neuroscience — Posted on 2018-03-18

970 Active vision varies across the cardiac cycle

Kunzendorf, S.; Klotzsche, F.; Akbal, M.; Villringer, A.; Ohl, S.; Gaebler, M.

10.1101/283838 — neuroscience — Posted on 2018-03-18

971 A re-examination of responding on ratio and regulated-probability interval schedules

Perez, O. D.; Milton, A. L.; Aitken, M. R. F.; Dickinson, A.

10.1101/284216 — animal behavior and cognition — Posted on 2018-03-18

972 The Pseudomonas aeruginosa LasR quorum-sensing receptor balances ligand selectivity and sensitivity

Bassler, B. L.; McCready, A. R.; Paczkowski, J. E.; Henke, B. R.

10.1101/269001 — microbiology — Posted on 2018-03-18

973 PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner

Stark, A.-K.; Chandra, A.; Chakraborty, K.; Alam, R.; Carbonaro, V.; Clark, J.; Sriskantharajah, S.; Bradley, G.; Richter, A. G.; Banham-Hall, E.; Clatworthy, M. R.; Nejentsev, S.; Hamblin, J. N.; Hessel, E. M.; Condliffe, A. M.; Okkenhaug, K.

10.1101/280651 — immunology — Posted on 2018-03-18

974 Extensive horizontal exchange of transposable elements in the Drosophila pseudoobscura group

Hill, T.; Betancourt, A.

10.1101/284117 — genomics — Posted on 2018-03-18

975 Genome-wide features of introns are evolutionary decoupled among themselves and from genome size throughout Eukarya

Lozada-Chavez, I.; Stadler, P. F.; Prohaska, S. J.

10.1101/283549 — evolutionary biology — Posted on 2018-03-18

976 Refactoring the upper sugar metabolism of Pseudomonas putida for co-utilization of disaccharides, pentoses, and hexoses

Dvorak, P.; de Lorenzo, V.

10.1101/284182 — synthetic biology — Posted on 2018-03-18

977 Gene expression across tissues, sex, and life stages in the sea urchin Tripneustes gratilla

Laruson, A. J.; Coppard, S. E.; Pespeni, M. H.; Reed, F. A.

10.1101/284224 — molecular biology — Posted on 2018-03-18

978 Selection signatures underlying dramatic male inflorescence transformation during modern hybrid maize breeding

Gage, J. L.; White, M. R.; Edwards, J.; Kaeppler, S.; de Leon, N.

10.1101/284109 — genetics — Posted on 2018-03-18

979 Auxin-Mediated Sterility Induction System for Longevity and Mating Studies in Caenorhabditis elegans

Kasimatis, K. R.; Moerdyk-Schauecker, M. J.; Phillips, P. C.

10.1101/284232 — genetics — Posted on 2018-03-18

980 Epigenetic inheritance of telomere length in wild birds

Bauch, C.; Boonekamp, J. J.; Korsten, P.; Mulder, E.; Verhulst, S.

10.1101/284208 — genetics — Posted on 2018-03-18

981 Phenotypic expansion in DDX3X -- a common cause of intellectual disability in females

Wang, X.; Rosenfeld, J. A.; Bacino, C. A.; Scaglia, F.; Immken, L.; Harris, J. M.; Hickey, S. E.; Mosher, T. M.; Slavotinek, A.; Zhang, J.; Beuten, J.; Leduc, M. S.; He, W.; Vetrini, F.; Walkiewicz, M.; Bi, W.; Xiao, R.; Shao, Y.; Gezdirici, A.; Jiang, Y.; Hansen, A.; Pehlivan, D.; Piard, J.; Muzny, D.; Hanchard, N.; Belmont, J.; van Maldergem, L.; Gibbs, R.; Eldomery, M.; Akdemir, Z.; Harel, T.; Posey, J. E.; Adesina, A.; Chen, S.; Members of the UDN, ; Lee, B.; Lupski, J. R.; Eng, C.; Xia, F.; Yang, Y.; Graham, B.; Moretti, P.

10.1101/283598 — genetics — Posted on 2018-03-18

982 Identify and predict environmental change effects on tiger mosquitos, Aedes polynesiensis

Grziwotz, F.; Strauss, J. F.; Hsieh, C.-h.; Telschow, A.

10.1101/284174 — ecology — Posted on 2018-03-18

983 Human sensory Long-Term Potentiation (LTP) predicts visual memory performance and is modulated by the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism

Spriggs, M. J.; Thompson, C. S.; Moreau, D.; McNair, N. A.; Wu, C. C.; Lamb, Y. N.; Mckay, N. S.; King, R. O. C.; Antia, U.; Shelling, A. N.; Hamm, J. P.; Teyler, T. J.; Russell, B. R.; Waldie, K. W.; Kirk, I. J.

10.1101/284315 — neuroscience — Posted on 2018-03-18

984 Role of anterograde motor Kif5b in clathrin-coated vesicle uncoating and clathrin-mediated endocytosis

Ni, Y.-X.; Xue, W.-Q.; Zhou, N.; Yung, W.-H.; Lin, R.-Z.; Kao, Y.-T.; Duan, Z.-G.; Tang, X.-M.; Liu, M.-F.; Zhang, W.; Qi, S.; Lu, X.-B.; Hu, J.-j.; Chung, S.; Song, Y.-Q.; Huang, J.-d.

10.1101/284166 — cell biology — Posted on 2018-03-18

985 EXD2 and WRN exonucleases are required for interstrand crosslink repair in Drosophila

Chennuri, P.; Cox, L. S.; Saunders, R. D. C.

10.1101/284307 — cell biology — Posted on 2018-03-18

986 Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

Sahu, A.; Sang Lee, J.; Zhang, G.; Wang, Z.; Tian, T.; Moll, T.; Kasumova, G.; Miao, B.; Wei, Z.; Nair, N. U.; Ponomarova, O.; Friedman, A.; Amzallag, A.; Greninger, P.; Egan, R.; Damon, L.; Frederick, D.; Jerby-Arnon, L.; Wagner, A.; Cheng, K.; Robinson, W.; Park, S. G.; Gardner, K.; Hannenhalli, S.; Gutkind, S.; Boland, G.; Flaherty, K.; Benes, C.; Herlyn, M.; Bartolome, R.; Ruppin, E.

10.1101/284240 — cancer biology — Posted on 2018-03-18

987 Chromosome compartmentalization replacement during stem cell differentiation

Eidelman, Y.; Slanina, S.; Pyatenko, V.; Andreev, S.

10.1101/284190 — biophysics — Posted on 2018-03-18

988 Protein phase separation provides long-term memory of transient spatial stimuli

Dine, E. A.; Gil, A. A.; Uribe, G.; Brangwynne, C. P.; Toettcher, J. E.

10.1101/283804 — systems biology — Posted on 2018-03-17

989 Clonal analysis reveals gradual recruitment of lateral root founder cells and a link between root initiation and cambium formation in Arabidopsis thaliana

Dubrovsky, J. G.

10.1101/283366 — plant biology — Posted on 2018-03-17

990 From proteins to polysaccharides: lifestyle and genetic evolution of Coprothermobacter proteolyticus.

Kunath, B.; Delogu, F.; Arntzen, M.; Eijsink, V. G. H.; Hvidsten, T. R.; Pope, P. B.

10.1101/280602 — microbiology — Posted on 2018-03-17

991 Individual Variation in Brain Network Topology Predicts Emotional Intelligence

Ling, G.; Lee, I.; Guimond, S.; Lutz, O.; Tandon, N.; Ongur, D.; Eack, S.; Lewandowski, K.; Keshavan, M.; Brady, R.

10.1101/275768 — neuroscience — Posted on 2018-03-17

992 Big data approaches to decomposing heterogeneity across the autism spectrum

Lombardo, M. V.; Lai, M.-C.; Baron-Cohen, S.

10.1101/278788 — neuroscience — Posted on 2018-03-17

993 YES1 amplification: a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics

Fan, P.-D.; Narzisi, G.; Jayaprakash, A. D.; Venturini, E.; Robine, N.; Smibert, P.; Germer, S.; Yu, H. A.; Jordan, E. J.; Paik, P. K.; Janjigian, Y. Y.; Chaft, J. E.; Wang, L.; Jungbluth, A. A.; Middha, S.; Spraggon, L.; Qiao, H.; Lovly, C. M.; Kris, M. G.; Riely, G. J.; Politi, K.; Varmus, H.; Ladanyi, M.

10.1101/275974 — cancer biology — Posted on 2018-03-17

994 Reproductive phasiRNAs in grasses are compositionally distinct from other classes of small RNAs

Patel, P.; Mathioni, S.; Kakrana, A.; Shatkay, H.; Meyers, B. C.

10.1101/242727 — plant biology — Posted on 2018-03-17

995 Cis-directed cleavage and nonstoichiometric abundances of 21-nt reproductive phasiRNAs in grasses

Tamim, S.; Cai, Z.; Mathioni, S.; Zhai, J.; Teng, C.; Zhang, Q.; Meyers, B. C.

10.1101/243907 — plant biology — Posted on 2018-03-17

996 Dynamic compression schemes for graph coloring

Mustafa, H.; Schilken, I.; Karasikov, M.; Eickhoff, C.; Ratsch, G.; Kahles, A.

10.1101/239806 — bioinformatics — Posted on 2018-03-17

997 Behavioral variation correlates with differences in single neuron serotonin receptor subtype expression within and across species

Tamvacakis, A. N.; Senatore, A.; Katz, P. S.

10.1101/231829 — neuroscience — Posted on 2018-03-17

998 Rethinking phylogenetic comparative methods

Uyeda, J. C.; Zenil-Ferguson, R.; Pennell, M. W.

10.1101/222729 — evolutionary biology — Posted on 2018-03-17

999 Placozoa and Cnidaria are sister taxa

Laumer, C. E.; Gruber-Vodicka, H.; Hadfield, M. G.; Pearse, V. B.; Riesgo, A.; Marioni, J. C.; Giribet, G.

10.1101/200972 — zoology — Posted on 2018-03-17

1000 Correcting for batch effects in case-control microbiome studies

Gibbons, S.; Duvallet, C.; Alm, E. J.

10.1101/165910 — bioinformatics — Posted on 2018-03-17

1001 Systematic conservation planning for intraspecific genetic diversity.

Paz-Vinas, I.; Loot, G.; Hermoso, V.; Veyssiere, C.; Poulet, N.; Grenouillet, G.; Blanchet, S.

10.1101/105544 — ecology — Posted on 2018-03-17

1002 Differential encoding of predator fear in the ventromedial hypothalamus and periaqueductal grey

Esteban Masferrer, M.; Silva, B. A.; Nomoto, K.; Lima, S. Q.; Gross, C. T.

10.1101/283820 — neuroscience — Posted on 2018-03-17

1003 Nonlinear functional responses and ecological pleiotropy alter the strength of disruptive selection in consumers

Coblentz, K. E.

10.1101/283911 — evolutionary biology — Posted on 2018-03-17

1004 The first next-generation sequencing approach to the mitochondrial phylogeny of African monogenean parasites (Platyhelminthes: Gyrodactylidae and Dactylogyridae)

Vanhove, M. P. M.; Briscoe, A. G.; Jorissen, M. W. P.; Littlewood, D. T. J.; Huyse, T.

10.1101/283788 — evolutionary biology — Posted on 2018-03-17

1005 Motor Responses Influence Perceptual Awareness Judgements

Siedlecka, M.; Hobot, J.; Skora, Z.; Paulewicz, B.; Timmermans, B.; Wierzchon, M.

10.1101/283762 — animal behavior and cognition — Posted on 2018-03-17

1006 Population dynamics of choice representation in dorsal premotor and primary motor cortex

Peixoto, D.; Kiani, R.; Chandrasekaran, C.; Ryu, S. I.; Shenoy, K. V.; Newsome, W. T.

10.1101/283960 — neuroscience — Posted on 2018-03-17

1007 Glutamatergic facilitation of neural responses in MT enhances motion perception in humans

Schallmo, M.-P.; Millin, R.; Kale, A. M.; Kolodny, T.; Edden, R. A. E.; Bernier, R. A.; Murray, S. O.

10.1101/283994 — neuroscience — Posted on 2018-03-17

1008 Genome-wide fitness assessment during diurnal growth reveals an expanded role of the cyanobacterial circadian clock protein KaiA

Welkie, D. G.; Rubin, B. E.; Chang, Y.-G.; Diamond, S.; Rifkin, S. A.; LiWang, A.; Golden, S. S.

10.1101/283812 — microbiology — Posted on 2018-03-17

1009 Voltage- and Branch-specific Climbing Fiber Responses in Purkinje Cells

Zang, Y.; Dieudonne, S.; De Schutter, E.

10.1101/284026 — neuroscience — Posted on 2018-03-17

1010 Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem

Venkatesh, D.; Poen, M. J.; Bestebroer, T. M.; Scheuer, R. D.; Vuong, O.; Chkhaidze, M.; Machablishvili, A.; Mamuchadze, J.; Ninua, L.; Fedorova, N. B.; Halpin, R. A.; Lin, X.; Ransier, A.; Stockwell, T. B.; Wentworth, D. E.; Kriti, D.; Dutta, J.; van Bakel, H.; Puranik, A.; Slomka, M. J.; Essen, S.; Brown, I. H.; Fouchier, R. A. M.; Lewis, N. S.

10.1101/282491 — microbiology — Posted on 2018-03-17

1011 Switch-like activation of Bruton’s tyrosine kinase by membrane-mediated dimerization

Chung, J. K.; Nocka, L. M.; Wang, Q.; Kadlecek, T. A.; Weiss, A.; Kuriyan, J.; Groves, J. T.

10.1101/284000 — biophysics — Posted on 2018-03-17

1012 Regional protein expression in human Alzheimer’s brain correlates with disease severity

Xu, J.; Patassini, S.; Rustogi, N.; Riba-Garcia, I.; Hale, B. D.; Phillips, A. M.; Waldvogel, H.; Haines, R.; Bradbury, P.; Stevens, A.; Faull, R. L.; Dowsey, A. W.; Cooper, G. J.; Unwin, R.

10.1101/283705 — neuroscience — Posted on 2018-03-17

1013 Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer’s Disease – An Emerging Role for Gut Microbiome

Mahmoudiandehkordi, S.; Arnold, M.; Nho, K.; Ahmad, S.; Jia, W.; Xia, G.; Louie, G.; Kueider, A.; Moseley, M. A.; Thompson, J. W.; St. John Williams, L.; Tenenbaum, J. D.; Blach, C.; Baillie, R.; Han, X.; Bhattacharyya, S.; Toledo, J. B.; Schafferer, S.; Klein, S.; Koal, T.; Risacher, S. L.; Kling, M. A.; Motsinger-Reif, A.; Rotroff, D. M.; Jack, J.; Hankemeier, T.; Bennett, D. A.; De Jager, P. L.; Trojanowski, J. Q.; Shaw, L. M.; Weiner, M. W.; Doraiswamy, P. M.; van Duijn, C. M.; Saykin, A.; Kastenmueller, G.; Kaddurah-Daouk, R.; Alzheimers Disease Neuroimaging Initiative, ; Alzheimers Dise

10.1101/281956 — neuroscience — Posted on 2018-03-17

1014 Targeting of NF-κB to Dendritic Spines is Required for Synaptic Signaling and Spine Development

Dresselhaus, E. C.; Boersma, M. C. H.; Meffert, M. K.

10.1101/283879 — neuroscience — Posted on 2018-03-17

1015 Axonal transport and active zone proteins regulate dopaminergic synapse formation

Lipton, D. M.; Maeder, C.; Shen, K.

10.1101/284042 — neuroscience — Posted on 2018-03-17

1016 Mathematical modelling of molecular heterogeneity identifies novel markers and subpopulations in complex tumors

Chen, L.; Wang, N.; Clarke, R.; Zhang, Z.; Wang, Y.

10.1101/283903 — bioinformatics — Posted on 2018-03-17

1017 Structures reveal opening of the store-operated calcium channel Orai

Hou, X.; Burstein, S. R.; Long, S.

10.1101/284034 — biochemistry — Posted on 2018-03-17

1018 Bacillus safensis FO-36b and Bacillus pumilus SAFR-032: A Whole Genome Comparison of Two Spacecraft Assembly Facility Isolates

Tirumalai, M.; Stepanov, V. G.; Wunsche, A.; Montazari, S.; Gonzalez, R. O.; Venkateswaran, K.; Fox, G. E.

10.1101/283937 — genomics — Posted on 2018-03-16

1019 Conformational footprinting of proteins using a combination of top-down electron transfer dissociation and ion mobility

Konijnenberg, A.; Li, J.; Habchi, J.; Dosnon, M.; Rossetti, G.; Grandori, R.; Longhi, S.; Carloni, P.; Sobott, F.

10.1101/283796 — biophysics — Posted on 2018-03-16

1020 Protein phase separation provides long-term memory of transient spatial stimuli

Dine, E. A.; Gil, A. A.; Uribe, G.; Brangwynne, C. P.; Toettcher, J. E.

10.1101/283804 — systems biology — Posted on 2018-03-16

1021 Flexible top-down modulation in human ventral temporal cortex

Zhang, R.; Kay, K.

10.1101/279935 — neuroscience — Posted on 2018-03-16

1022 A drug-tunable gene therapy for broad-spectrum protection against retinal degeneration

Santiago, C. P.; Keuthan, C. J.; Boye, S.; Boye, S.; Imam, A. A.; Ash, J. D.

10.1101/283887 — bioengineering — Posted on 2018-03-16

1023 Rethinking the importance of the structure of ecological networks under an environment-dependent framework

Cenci, S.; Song, C.; Saavedra, S.

10.1101/219691 — ecology — Posted on 2018-03-16

1024 Natural selection on plasticity of thermal traits in a highly seasonal environment

Bacigalupe, L. D.; Gaitan-Espitia, J. D.; Barria, A. M.; Gonzalez, A.; Ruiz-Aravena, M.; Trinder, M.; Sinervo, B.

10.1101/191825 — evolutionary biology — Posted on 2018-03-16

1025 Pollen Patterns Form from Modulated Phases

Radja, A.; Horsley, E. M.; Lavrentovich, M. O.; Sweeney, A. M.

10.1101/279851 — biophysics — Posted on 2018-03-16

1026 Phenotyping ciliary dynamics and coordination in response to CFTR-modulators in Cystic Fibrosis respiratory epithelial cells

Chioccioli, M.; Feriani, L.; Kotar, J.; Bratcher, P. E.; Cicuta, P.

10.1101/223024 — physiology — Posted on 2018-03-16

1027 Inter-population variation in the Atlantic salmon microbiome reflects environmental and genetic diversity

Uren Webster, T. M.; Consuegra, S.; Hitchings, M.; Garcia de Leaniz, C.

10.1101/283754 — ecology — Posted on 2018-03-16

1028 CHARACTERIZATION OF THE bHLH FAMILY OF TRANSCRIPTIONAL REGULATORS IN THE ACOEL S. roscoffensis AND THEIR PUTATIVE ROLE IN NEUROGENESIS

Perea-Atienza, E.; Sprecher, S. G.; Martinez, P.

10.1101/237388 — developmental biology — Posted on 2018-03-16

1029 Dynamics of sister chromatid resolution during cell cycle progression

Stanyte, R.; Nuebler, J.; Blaukopf, C.; Hoefler, R.; Stocsits, R.; Peters, J.-M.; Gerlich, D. W.

10.1101/283770 — cell biology — Posted on 2018-03-16

1030 An eQTL landscape of kidney tissue in human nephrotic syndrome

Gillies, C. E.; Putler, R.; Menon, R.; Otto, E.; Yasutake, K.; Nair, V.; Hoover, P.; Lieb, D.; Li, S.; Fermin, D.; Eddy, S.; Vega-Warner, V.; Nephrotic Syndrome Study Network, ; Hacohen, N.; Kiryluk, K.; Wen, X.; Kretzler, M.; Sampson, M.

10.1101/281162 — genomics — Posted on 2018-03-16

1031 Genome-wide gene-environment analyses of depression and reported lifetime traumatic experiences in UK Biobank

Coleman, J; Purves, K; Davis, K; Rayner, C; Choi, S; Hübel, C; Gaspar, H; Kan, C; Van der Auwera, S; Adams, M; Lyall, D; Peyrot, W; Dunn, E; Vassos, E; Danese, A; Grabe, H; Lewis, C; O'Reilly, P; McIntosh, A; Smith, D; Wray, N; Hotopf, M; Eley, T; Breen, G

10.1101/247353 — genomics — Posted on 2018-03-16

1032 Bayesian model comparison for rare variant association studies of multiple phenotypes

DeBoever, C.; Aguirre, M.; Tanigawa, Y.; Spencer, C. C. A.; Poterba, T.; Bustamante, C. D.; Daly, M. J.; Pirinen, M.; Rivas, M. A.

10.1101/257162 — genetics — Posted on 2018-03-16

1033 Selection in parental species predicts hybrid evolution

Runemark, A.; Bailey, R. I.; Bache-Mathiesen, L.; Saetre, G.-P.

10.1101/283689 — evolutionary biology — Posted on 2018-03-16

1034 An Algorithmic Information Calculus for Causal Discovery and Reprogramming Systems

Zenil, H.; Kiani, N. A.; Marabita, F.; Deng, Y.; Elias, S.; Schmidt, A.; Ball, G.; Tegner, J.

10.1101/185637 — systems biology — Posted on 2018-03-16

1035 Acute alcohol administration dampens threat-related activation in the central extended amygdala

Hur, J.; Kaplan, C. M.; Smith, J. F.; Bradford, D. E.; Fox, A. S.; Curtin, J. J.; Shackman, A. J.

10.1101/283358 — neuroscience — Posted on 2018-03-16

1036 Comparison of decision-related signals in sensory and motor preparatory responses of neurons in Area LIP

Shushruth, S.; Mazurek, M. E.; Shadlen, M. N.

10.1101/169219 — neuroscience — Posted on 2018-03-16

1037 Adipose fin development and its relation to the evolutionary origins of median fins

Stewart, T.; Ho, R.; Hale, M. A.

10.1101/283432 — evolutionary biology — Posted on 2018-03-16

1038 DNA crookedness regulates DNA mechanical properties at short length scales

Marin-Gonzalez, A.; Vilhena, J. G.; Moreno-Herrero, F.; Perez, R.

10.1101/283648 — biophysics — Posted on 2018-03-16

1039 Mapping local and global liquid-liquid phase behavior in living cells using light-activated multivalent seeds

Bracha, D.; Walls, M. T.; Wei, M.-T.; Zhu, L.; Kurian, M.; Toettcher, J. E.; Brangwynne, C. P.

10.1101/283655 — biophysics — Posted on 2018-03-16

1040 IRIS-DGE: An integrated RNA-seq data analysis and interpretation system for differential gene expression

Monier, B.; McDermaid, A.; Zhao, J.; Fennell, A.; Ma, Q.

10.1101/283341 — bioinformatics — Posted on 2018-03-16

1041 Harnessing Empirical Bayes and Mendelian Segregation for Genotyping Autopolyploids from Messy Sequencing Data

Gerard, D.; Ferrao, L. F. V.; Garcia, A. A. F.; Stephens, M.

10.1101/281550 — bioinformatics — Posted on 2018-03-16

1042 Uncovering novel pathways for enhancing hyaluronan synthesis in recombinant Lactococcus lactis: Genome-scale metabolic modelling and experimental validation

Badri, A.; Raman, K.; Jayaraman, G.

10.1101/244699 — bioengineering — Posted on 2018-03-16

1043 Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces

Brennan, P.; Bowkett, D.; Talon, R.; Tallant, C.; Schofield, C.; Von Delft, F.; Knapp, S.; Bruton, G.

10.1101/283069 — biochemistry — Posted on 2018-03-16

1044 Evidence that the cell cycle is a series of uncoupled, memoryless phases

Chao, H. X.; Fakhreddin, R. I.; Shimerov, H. K.; Kumar, R. J.; Gupta, G. P.; Purvis, J. E.

10.1101/283614 — systems biology — Posted on 2018-03-16

1045 E93 expression and links to the juvenile hormone in hemipteran mealybugs with insights on female neoteny

Vea, I. M.; Tanaka, S.; Tsuji, T.; Shiotsuki, T.; Jouraku, A.; Minakuchi, C.

10.1101/283556 — molecular biology — Posted on 2018-03-16

1046 Transcriptomic analysis of the early strobilar development of Echinococcus granulosus

Debarba, J. A.; Monteiro, K. M.; Gerber, A. L.; de Vasconcelos, A. T. R.; Zaha, A.

10.1101/271767 — molecular biology — Posted on 2018-03-16

1047 Nucleosome remodelling at origins of Global Genome-Nucleotide Excision Repair occurs at the boundaries of higher-order chromatin structure

van Eijk, P.; Nandi, S. P.; Yu, S.; Bennett, M.; Leadbitter, M.; Teng, Y.; Reed, S.

10.1101/283747 — genomics — Posted on 2018-03-16

1048 Mean-Variance QTL Mapping on a Background of Variance Heterogeneity

Corty, R. W.; Valdar, W.

10.1101/276980 — genetics — Posted on 2018-03-16

1049 Detecting archaic introgression without archaic reference genomes

Skov, L.; Hui, R.; Hobolth, A.; Scally, A.; Schierup, M. H.; Durbin, R.

10.1101/283606 — evolutionary biology — Posted on 2018-03-16

1050 P-bodies and the miRNA pathway regulate translational repression of bicoid mRNA during Drosophila melanogaster oogenesis

McLaughlin, J. M.; Smith, D. F.; Catrina, I. E.; Bratu, D. P.

10.1101/283630 — cell biology — Posted on 2018-03-16

1051 YES1 amplification: a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics

10.1101/275974 — cancer biology — Posted on 2018-03-16

1052 LimoRhyde: a flexible approach for differential analysis of rhythmic transcriptome data

Hughey, J. J.

10.1101/283622 — bioinformatics — Posted on 2018-03-16

1053 Fast NeighborNet: Improving the Speed of the Neighbor-Net Phylogenetic Network Algorithm with Multithreading and a Relaxed Search Strategy

Porter, J.

10.1101/283424 — bioinformatics — Posted on 2018-03-16

1054 Continuous-trait probabilistic model for comparing multi-species functional genomic data

Yang, Y.; Gu, Q.; Zhang, Y.; Sasaki, T.; Crivello, J.; O'Neill, R. J.; Gilbert, D. M.; Ma, J.

10.1101/283093 — bioinformatics — Posted on 2018-03-16

1055 Iron-dependent essential genes in Salmonella Typhimurium

Karash, S.; Kwon, Y. M.

10.1101/159921 — microbiology — Posted on 2018-03-16

1056 Modeling Codon Rate Variation: Robust Inference of Protein and Nucleotide Selection

Davydov, I. I.; Salamin, N.; Robinson-Rechavi, M.

10.1101/174839 — bioinformatics — Posted on 2018-03-16

1057 Hypertension and diabetes mellitus association to oxidative stress in an elderly population

Rodriguez-Castaneda, A.; Martinez-Gonzales, K. L.; Sanchez-Arenas, R.; Sanchez-Garcia, S.; Grijalva, I.; Basurto, L.; Cuadros-Moreno, J.; Ramirez-Garcia, E.; Garcia-delaTorre, P.

10.1101/269993 — epidemiology — Posted on 2018-03-16

1058 Experimental loss of generalist plants reveals alterations in plant-pollinator interactions and a constrained flexibility of foraging

Biella, P.; Akter, A.; Ollerton, J.; Tarrant, S.; Janecek, S.; Jersakova, J.; Klecka, J.

10.1101/279430 — ecology — Posted on 2018-03-16

1059 Evaluating Tumor Evolution via Genomic Profiling of Individual Tumor Spheroids in a Malignant Ascites from a Patient with Ovarian Cancer Using a Laser-aided Cell Isolation Technique

Kim, S.; Kim, S.; Kim, J.; Kim, B.; Kim, S. I.; Kim, M. A.; Kwon, S.; Song, Y. S.

10.1101/282277 — cancer biology — Posted on 2018-03-16

1060 babette: BEAUti 2, BEAST2 and Tracer for R

Bilderbeek, R. J. C.; Etienne, R. S.

10.1101/271866 — bioinformatics — Posted on 2018-03-16

1061 A role for Fibroblast Growth Factor Receptor 1 in the pathogenesis of Neisseria meningitidis

Azimi, S.; Wheldon, L. M.; Oldfield, N. J.; Ala'Aldeen, D. A. A.; Wooldridge, K.

10.1101/283028 — microbiology — Posted on 2018-03-16

1062 Pathway-based dissection of the genomic heterogeneity of cancer hallmarks’ acquisition with SLAPenrich

Iorio, F.; Garcia-Alonso, L.; Brammeld, J. S.; Martincorena, I.; Wille, D. R.; McDermott, U.; Saez-Rodriguez, J.

10.1101/077701 — bioinformatics — Posted on 2018-03-16

1063 Tychus: a whole genome sequencing pipeline for assembly, annotation and phylogenetics of bacterial genomes

Dean, C.; Noyes, N.; Lakin, S. M.; Rovira-Sanz, P.; Yang, X.; Belk, K.; Morley, P.; Meinersmann, R.; Abdo, Z.

10.1101/283101 — bioinformatics — Posted on 2018-03-16

1064 Multiple large-scale gene and genome duplications during the evolution of hexapods

Li, Z.; Tiley, G.; Galuska, S.; Reardon, C.; Kidder, T.; Rundell, R.; Barker, M. S.

10.1101/253609 — evolutionary biology — Posted on 2018-03-16

1065 CCA based multi-view feature selection for multi-omics data integration

EL-Manzalawy, Y.

10.1101/243733 — bioinformatics — Posted on 2018-03-16

1066 Bayesian model comparison for rare variant association studies of multiple phenotypes

DeBoever, C.; Aguirre, M.; Tanigawa, Y.; Spencer, C. C. A.; Poterba, T.; Bustamante, C. D.; Daly, M. J.; Pirinen, M.; Rivas, M. A.

10.1101/257162 — genetics — Posted on 2018-03-16

1067 Meta-analysis challenges a textbook example of status signalling: evidence for publication bias

Sanchez-Tojar, A.; Nakagawa, S.; Sanchez-Fortun, M.; Martin, D. A.; Ramani, S.; Girndt, A.; Bokony, V.; Kempenaers, B.; Liker, A.; Westneat, D.; Burke, T.; Schroeder, J.

10.1101/283150 — evolutionary biology — Posted on 2018-03-16

1068 The impact of genome-wide association studies on biomedical research publications

Struck, T. J.; Mannakee, B. K.; Gutenkunst, R. N.

10.1101/106773 — genetics — Posted on 2018-03-16

1069 Genome-wide profiling of an enhancer-associated histone modification reveals the influence of asthma on the epigenome of the airway epithelium.

McErlean, P.; Kelly, A.; Dhariwal, J.; Kirtland, M.; Watson, J.; Ranz Jimenez, I.; Saxena, A.; Cousins, D.; Solari, R.; Edwards, M. R.; Johnston, S. l.; Lavender, P.

10.1101/282889 — genomics — Posted on 2018-03-16

1070 Lilikoi: an R package for personalized pathway-based classification modeling using metabolomics data

Alakwaa, F.; Huang, S.; Garmire, L.

10.1101/283408 — bioinformatics — Posted on 2018-03-16

1071 Differential brain mechanisms of selection and maintenance of information during working memory

Quentin, R.; King, J.-R.; Sallard, E.; Fishman, N.; Thompson, R.; Buch, E.; Cohen, L. G.

10.1101/283234 — neuroscience — Posted on 2018-03-16

1072 Transposable elements and gene expression during the evolution of amniotes

Zeng, L.; Pederson, S.; Kortschak, D.; Adelson, D.

10.1101/283390 — evolutionary biology — Posted on 2018-03-16

1073 A machine-learning-guided mutagenesis platform for accelerated discovery of novel functional proteins

Saito, Y.; Oikawa, M.; Nakazawa, H.; Niide, T.; Kameda, T.; Tsuda, K.; Umetsu, M.

10.1101/282996 — bioengineering — Posted on 2018-03-16

1074 A Measure of Open Data: A Metric and Analysis of Reusable Data Practices in Biomedical Data Resources

Carbon, S.; Champieux, R.; McMurry, J.; Winfree, L.; Wyatt, L. R.; Haendel, M.

10.1101/282830 — scientific communication and education — Posted on 2018-03-16

1075 Polycomb repressive complex 1 defines the nucleosome landscape but not accessibility at target genes.

King, H. W.; Klose, R. J.

10.1101/280305 — genomics — Posted on 2018-03-16

1076 The efficacy of sexual selection under environmental change

Martinossi-Allibert, I.; Rueffler, C.; Arnqvist, G.; Berger, D.

10.1101/283457 — evolutionary biology — Posted on 2018-03-16

1077 Selection for synchronized cell division in simple multicellular organisms

Olejarz, J.; Kaveh, K.; Veller, C.; Nowak, M. A.

10.1101/283523 — evolutionary biology — Posted on 2018-03-16

1078 Differences in tropical vs. temperate diversity in arthropod predators provide insights into causes of latitudinal gradients of species diversity

Privet, K.; Petillon, J.

10.1101/283499 — ecology — Posted on 2018-03-16

1079 Protocadherin-mediated cell repulsion controls the central topography and efferent projections of the abducens nucleus

Asakawa, K.; Kawakami, K.

10.1101/283473 — neuroscience — Posted on 2018-03-16

1080 Determining the specificity of Cascade binding, interference, and primed adaptation in vivo in the Escherichia coli type I-E CRISPR-Cas system

Cooper, L.; Stringer, A.; Wade, J.

10.1101/169011 — microbiology — Posted on 2018-03-16

1081 Repeat-driven generation of antigenic diversity in a major human pathogen, Trypanosoma cruzi

Talavera-Lopez, C.; Messenger, L. A.; Lewis, M. D.; Yeo, M.; Reis-Cunha, J. L.; Bartholomeu, D. C.; Calzada, J. E.; Saldana, A.; Ramirez, J. D.; Guhl, F.; Ocana-Mayorga, S.; Costales, J. A.; Gorchakov, R.; Jones, K.; Nolan Garcia, M.; Carrasco, H.; Grisard, E. C.; Teixeira, S. M. R.; Bottazzi, M. E.; Hotez, P. J.; Murray, K. O.; Grijalva, M. J.; Burleigh, B.; Miles, M. A.; Andersson, B.

10.1101/283531 — genomics — Posted on 2018-03-16

1082 Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

Gilly, A.; Suveges, D.; Kuchenbaecker, K.; Pollard, M. O.; Southam, L.; Hatzikotoulas, K.; Farmaki, A.-E.; Bjornland, T.; Waples, R.; Appel, E. V.; Casalone, E.; Melloni, G.; Kilian, B.; Rayner, N. W.; Ntalla, I.; Kundu, K.; Walter, K.; Danesh, J.; Butterworth, A.; Barroso, I.; Tsafantakis, E.; Dedoussis, G.; Moltke, I.; Zeggini, E.

10.1101/283481 — genetics — Posted on 2018-03-16

1083 Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels

Wu, J.-X.; Ding, D.; Wang, M.; Kang, Y.; Zeng, X.; Chen, L.

10.1101/283440 — biophysics — Posted on 2018-03-16

1084 The complex architecture of plant transgene insertions

Jupe, F.; Rivkin, A. C.; Michael, T. P.; Zander, M.; Motley, T. S.; Sandoval, J. P.; Slotkin, K. R.; Chen, H.; Castagnon, R.; Nery, J. R.; Ecker, J. R.

10.1101/282772 — plant biology — Posted on 2018-03-16

1085 Clonal analysis reveals gradual recruitment of lateral root founder cells and a link between root initiation and cambium formation in Arabidopsis thaliana

Dubrovsky, J. G. G.

10.1101/283366 — plant biology — Posted on 2018-03-16

1086 The identification of an anti-thrombin molecule via the screening of semi-random DNA libraries

Feng, F.; Li, Z.; Chen, Z.; Wang, L.; Huang, J.; Wan, Y.; Shi, Y.; Liu, Q.

10.1101/282806 — molecular biology — Posted on 2018-03-16

1087 Asynchronous suppression of visual cortex during absence seizures

Meyer, J.; Maheshwari, A.; Noebels, J.; Smirnakis, S.

10.1101/282616 — neuroscience — Posted on 2018-03-15

1088 Ecological patterns are robust to use of exact sequence variants versus operational taxonomic units

Glassman, S. I.; Martiny, J. B.

10.1101/283283 — microbiology — Posted on 2018-03-15

1089 Cochaperones enable Hsp70 to fold proteins like a Maxwell’s demon

Xu, H.

10.1101/283143 — biophysics — Posted on 2018-03-15

1090 Clustered, information-dense transcription factor binding sites identify genes with similar tissue-wide expression profiles

Lu, R.; Rogan, P. K.

10.1101/283267 — bioinformatics — Posted on 2018-03-15

1091 Discrete Modeling Dynamical Systems That Determine the Role of Biodiversity in Different Regimes of Using Resources at Different Levels of Organization of Living Matter

Bespalov, Y.

10.1101/281279 — systems biology — Posted on 2018-03-15

1092 Estimating mechanical properties of cloth from videos using dense motion trajectories: human psychophysics and machine learning

Bi, W.; Jin, P.; Nienborg, H.; Xiao, B.

10.1101/238782 — neuroscience — Posted on 2018-03-15

1093 In vivo cloning of β 1-4 endoglucanase gene of Serratia liquefaciens using Muduction and its in silico analysis

Gowri Sankar, S.; Asnet Mary, J.; John Vennison, S.; Alwin Prem Anand, A.

10.1101/283226 — microbiology — Posted on 2018-03-15

1094 Thirty clues to the exceptional diversification of flowering plants

Magallon, S.; Sanchez-Reyes, L.; Gomez Acevedo, S.

10.1101/279620 — evolutionary biology — Posted on 2018-03-15

1095 CLADES: A Classification-based Machine Learning Method for Species Delimitation from Population Genetic Data

Pei, J.; Chu, C.; Li, X.; Lu, B.; Wu, Y.

10.1101/282608 — evolutionary biology — Posted on 2018-03-15

1096 Protected area effectiveness for fish spawning habitat in relation to earthquake-induced landscape change

Orchard, S.; Hickford, M.

10.1101/283333 — ecology — Posted on 2018-03-15

1097 FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data

10.1101/272476 — bioinformatics — Posted on 2018-03-15

1098 Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of cerebellar CHIPopathy

Shi, C.-h.; Rubel, C.; Soss, S. E.; Sanchez-Hodge, R.; Zhang, S.; Stevens, D. A.; McDonough, H.; Page, R. C.; Chazin, W.; Patterson, C.; Mao, C.-y.; Willis, M. S.; Luo, H.-Y.; Tang, M.-b.; Du, P.; Wang, Y.-h.; Hu, Z.-w.; Xu, Y.-M.; Schisler, J.

10.1101/283192 — animal behavior and cognition — Posted on 2018-03-15

1099 Mutant Plasticity Related Gene 1 (PRG1) acts as a potential modifier in SCN1A related epilepsy

Knierim, E.; Vogt, J.; Kintscher, M.; Ponomarenko, A.; Baumgart, J.; Sanker Beed, P.; Korotkova, T.; Trimbuch, T.; Panzer, A.; Stephani, U.; Escayg, A.; Lerche, H.; Nitsch, R.; Schmitz, D.; Schuelke, M.

10.1101/282871 — neuroscience — Posted on 2018-03-15

1100 Previously characterized Caenorhabditis elegans RNA interference-resistant mutants retain substantial silencing capacity

Watts, J. L.; Watts, J. S.; Dalelio, J.; Guenther, Q.

10.1101/283325 — molecular biology — Posted on 2018-03-15

1101 Emergence of carbapenem, beta-lactamase inhibitor and cefoxitin resistant lineages from a background of ESBL-producing Klebsiella pneumoniae and K. quasipneumoniae highlights different evolutionary mechanisms

Heinz, E.; Ejaz, H.; Bartholdson-Scott, J.; Wang, N.; Guanjaran, S.; Pickard, D.; Wilksch, J.; Cao, H.; ul-Haq, I.; Dougan, G.; Strugnell, R.

10.1101/283291 — genomics — Posted on 2018-03-15

1102 Variability and compensation of cardiomycoyte ionic conductances at the population level

Rees, C.; Yang, J.-H.; Santolini, M.; Lusis, A. J.; Weiss, J. N.; Karma, A.

10.1101/283275 — biophysics — Posted on 2018-03-15

1103 Progressive impairment of directional and spatially precise trajectories by TgF344-AD Rats in the Morris Water Task

Berkowitz, L. E.; Harvey, R. E.; Drake, E.; Thompson, S. M.; Clark, B. J.

10.1101/282392 — neuroscience — Posted on 2018-03-15

1104 Dissociation between CSD-evoked metabolic perturbations and meningeal afferent activation and sensitization: implications for mechanisms of migraine headache onset

Zhao, J.; Levy, D.

10.1101/149278 — neuroscience — Posted on 2018-03-15

1105 Positional information specifies the site of organ regeneration and not tissue maintenance in planarians

Hill, E. M.; Petersen, C. P.

10.1101/282657 — developmental biology — Posted on 2018-03-15

1106 Meaning Guides Attention in Real-World Scene Images: Evidence from Eye Movements and Meaning Maps

Henderson, J. M.; Hayes, T. R.

10.1101/207076 — neuroscience — Posted on 2018-03-15

1107 Using supervised learning methods for gene selection in RNA-Seq case-control studies

Wenric, S.; Shemirani, R.

10.1101/282780 — bioinformatics — Posted on 2018-03-15

1108 Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT.

Zhang, Y.-W.; Tavoulari, S.; Sinning, S.; Aleksandrova, A.; Forrest, L. R.; Rudnick, G.

10.1101/283176 — biochemistry — Posted on 2018-03-15

1109 Spatial summation in the human fovea: the effect of optical aberrations and fixational eye movements

Tuten, W. S.; Cooper, R. F.; Tiruveedhula, P.; Dubra, A.; Roorda, A.; Cottaris, N. P.; Brainard, D. H.; Morgan, J. I. W.

10.1101/283119 — neuroscience — Posted on 2018-03-15

1110 The network properties of the brain at the time of normal birth support the acquisition of language processing

Salvan, P.; Arichi, T.; Vidaurre, D.; Tournier, J. D.; Falconer, S.; Chew, A.; Counsell, S. J.; Edwards, A. D.

10.1101/282673 — neuroscience — Posted on 2018-03-15

1111 A new view of dorsal visual cortex in macaques revealed by submillimeter fMRI

Zhu, Q.; Vanduffel, W.

10.1101/283051 — neuroscience — Posted on 2018-03-15

1112 Would an RRS by any other name sound as RAD?

Campbell, E.; Brunet, B. M.; Dupuis, J. R.; Sperling, F. A.

10.1101/283085 — genomics — Posted on 2018-03-15

1113 A genetic perspective on the relationship between eudaimonic -and hedonic well-being

Baselmans, B. M.; Bartels, M.

10.1101/283036 — genetics — Posted on 2018-03-15

1114 Long-read DNA metabarcoding of ribosomal rRNA in the analysis of fungi from aquatic environments

Heeger, F.; Bourne, E. C.; Baschien, C.; Yurkov, A.; Bunk, B.; Spröer, C.; Overmann, J.; Mazzoni, C. J.; Monaghan, M. T.

10.1101/283127 — ecology — Posted on 2018-03-15

1115 An improved method for fitting gamma distribution to substitution rate variation among sites

Xia, X.

10.1101/276329 — bioinformatics — Posted on 2018-03-15

1116 Measuring proteomes with long strings: A new, unconstrained paradigm in mass spectrum interpretation

Devabhaktuni, A.; Olsson, N.; Gonzalez, C. G.; Rawson, K.; Swaminathan, K.; Elias, J. E.

10.1101/282624 — bioinformatics — Posted on 2018-03-15

1117 Implications for human odor sensing revealed from the statistics of the odorant-receptor interactions

Bak, J. H.; Jang, S.; Hyeon, C.

10.1101/283010 — systems biology — Posted on 2018-03-15

1118 Inhibitory Units: An Organizing Nidus for Feature-Selective Sub-Networks in Area V1.

Palagina, G.; Meyer, J. F.; Smirnakis, S. M.

10.1101/282988 — neuroscience — Posted on 2018-03-15

1119 Normalization models of cue combination in touch

Rahman, M. S.; Yau, J. M.

10.1101/283218 — neuroscience — Posted on 2018-03-15

1120 Shifted balance of dorsal versus ventral striatal communication with frontal reward and regulatory regions in cannabis dependence

Zhou, F.; Zimmermann, K.; Fei, X.; Scheele, D.; Dau, W.; Banger, M.; Weber, B.; Hurlemann, R.; Kendrick, K.; Becker, B.

10.1101/282939 — neuroscience — Posted on 2018-03-15

1121 On the flexibility of basic risk attitudes in monkeys

Farashahi, S.; Azab, H.; Hayden, B.; Soltani, A.

10.1101/282566 — neuroscience — Posted on 2018-03-15

1122 Distinct housing conditions reveal a major impact of adaptive immunity on the course of obesity-induced type 2 diabetes

Sbierski-Kind, J.; Kath, J.; Brachs, S.; Streitz, M.; von Herrath, M.; Kuehl, A.; Schmidt-Bleek, K.; Mai, K.; Spranger, J.; Volk, H.-D.

10.1101/282921 — immunology — Posted on 2018-03-15

1123 Single-nucleotide and Copy-number variance related to severity of Hypospadias

Singh, N.; Gupta, D. K.; Sharma, S.; Sahu, D. K.; Mishra, A.; Yadav, D. K.; Rawat, J.; Singh, A. K.

10.1101/282459 — genomics — Posted on 2018-03-15

1124 GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

Bovijn, J.; Jackson, L.; Censin, J.; Chen, C.-Y.; Laisk-Podar, T.; Laber, S.; Ferreira, T.; Glastonbury, C.; Smoller, J.; Harrison, J. W.; Ruth, K. S.; Beaumont, R. N.; Jones, S. E.; Tyrrell, J.; Wood, A. R.; Weedon, M. N.; Mägi, R.; Neale, B.; Lindgren, C. M.; Murray, A.; Holmes, M. V.

10.1101/283002 — genomics — Posted on 2018-03-15

1125 An optimized electroporation approach for efficient CRISPR/Cas9 genome editing in murine zygotes

Tröder, S. E.; Ebert, L. K.; Butt, L.; Assenmacher, S.; Schermer, B.; Zevnik, B.

10.1101/281402 — genetics — Posted on 2018-03-15

1126 Cytoplasmic sequestration of the RhoA effector mDiaphanous1 by Prohibitin2 promotes muscle differentiation

Dhawan, J.; Saleh, A.; Subramaniam, G.; Raychaudhuri, S.

10.1101/283044 — cell biology — Posted on 2018-03-15

1127 BAP1 Loss Predicts Therapeutic Vulnerability in Malignant Peritoneal Mesothelioma

Shrestha, R.; Nabavi, N.; Lin, Y.-Y.; Mo, F.; Anderson, S.; Volik, S.; Adomat, H. H.; Lin, D.; Xue, H.; Dong, X.; Shukin, R.; Bell, R. H.; McConeghy, B.; Haegert, A.; Brahmbhatt, S.; Li, E.; Oo, H. Z.; Hurtado-Coll, A.; Fazli, L.; Zhou, J.; McConnell, Y.; McCart, A.; Lowy, A.; Morin, G. B.; Daugaard, M.; Sahinalp, S. C.; Hach, F.; Le Bihan, S.; Gleave, M. E.; Wang, Y.; Churg, A.; Collins, C. C.

10.1101/243477 — cancer biology — Posted on 2018-03-15

1128 Tychus: a whole genome sequencing pipeline for assembly, annotation and phylogenetics of bacterial genomes

Dean, C.; Noyes, N.; Lakin, S. M.; Rovira-Sanz, P.; Yang, X.; Belk, K.; Morley, P.; Meinersmann, R.; Abdo, Z.

10.1101/283101 — bioinformatics — Posted on 2018-03-15

1129 DIA-NN: Deep neural networks substantially improve the identification performance of Data-independent acquisition (DIA) in proteomics

Demichev, V.; Messner, C. B.; Lilley, K. S.; Ralser, M.

10.1101/282699 — bioinformatics — Posted on 2018-03-15

1130 A role for Fibroblast Growth Factor Receptor 1 in the pathogenesis of Neisseria meningitidis

Wooldridge, K.; Azimi, S.; Wheldon, L. M.; Oldfield, N. J.; Ala'Aldeen, D. A. A.

10.1101/283028 — microbiology — Posted on 2018-03-15

1131 Effects of Temperatures and High Pressures on the Growth and Survivability of Methanogens and Stable Carbon Isotope Fractionation: Implications for Deep Subsurface Life on Mars

Sinha, N.; Nepal, S.; Kral, T.; Kumar, P.

10.1101/281105 — microbiology — Posted on 2018-03-15

1132 Immunostimulatory guide RNAs mediate potent antiviral response

Cai, Y.; Knudsen, A.; Windross, S. J.; Thomsen, M. K.; Paludan, S. R.

10.1101/282558 — immunology — Posted on 2018-03-15

1133 From Estimation to Prediction of Genomic Variances: Allowing for Linkage Disequilibrium and Unbiasedness

Schreck, N.; Schlather, M.

10.1101/282343 — genomics — Posted on 2018-03-15

1134 Cohesiveness in microbial community coalescence

Lu, N.; Sanchez-Gorostiaga, A.; Tikhonov, M.; Sanchez, A.

10.1101/282723 — ecology — Posted on 2018-03-15

1135 Rapid and Accurate Interpretation of Clinical Exomes Using Phenoxome: a Computational Phenotype-driven Approach

Wu, C.; Devkota, B.; Zhao, X.; Baker, S. W.; Niazi, R.; Kajia, C.; Gonzalez, M. A.; Jayaraman, P.; Conlin, L. K.; Krock, B. L.; Deardorff, M. A.; Spinner, N. B.; Krantz, I. D.; Santani, A. B.; Abou Tayoun, A. N.; Sarmady, M.

10.1101/275479 — bioinformatics — Posted on 2018-03-15

1136 Prediction-related neural activity during silent periods is sharply tuned

Demarchi, G.; Sanchez, G.; Weisz, N.

10.1101/266841 — neuroscience — Posted on 2018-03-15

1137 Forfeiting the founder effect: turnover defines biofilm community succession

Brislawn, C. J.; Graham, E. B.; Dana, K.; Ihardt, P.; Fansler, S. J.; Chirlser, W. B.; Cliff, J. B.; Stegen, J. C.; Moran, J. J.; Bernstein, H. C.

10.1101/282574 — ecology — Posted on 2018-03-15

1138 Using supervised learning methods for gene selection in RNA-Seq case-control studies

Wenric, S.; Shemirani, R.

10.1101/282780 — bioinformatics — Posted on 2018-03-15

1139 Endoglycosidase S enables a highly simplified clinical chemistry assay procedure for direct assessment of serum IgG undergalactosylation in chronic inflammatory disease

Vanderschaeghe, D.; Meuris, L.; Raes, T.; Grootaert, H.; Van Hecke, A.; Verhelst, X.; Van de Velde, F.; Lapauw, B.; Van Vlierberghe, H.; Callewaert, N.

10.1101/269795 — biochemistry — Posted on 2018-03-15

1140 High frequency electrical stimulation induces a long-lasting enhancement of event-related potentials but does not change the perception elicited by intra-epidermal electrical stimuli delivered to the area of secondary mechanical hyperalgesia

Biurrun Manresa, J.; Kaeseler Andersen, O.; Mouraux, A.; van den Broeke, E.

10.1101/282335 — neuroscience — Posted on 2018-03-15

1141 Transcriptional repression by FACT is linked to regulation of chromatin accessibility at the promoter of ES cells

Tessarz, P.; Mylonas, C.

10.1101/251611 — molecular biology — Posted on 2018-03-15

1142 A simple mung bean infection model for studying the virulence of Pseudomonas aeruginosa

Garge, S.; Azimi, S.; Diggle, S. P.

10.1101/229757 — microbiology — Posted on 2018-03-15

1143 Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging.

Heinze, I.; Bens, M.; Calzia, E.; Holtze, S.; Dakhovnik, O.; Sahm, A.; Kirkpatrick, J.; Szafranski, K.; Romanov, N.; Holzer, K.; Singer, S.; Ermolaeva, M.; Platzer, M.; Hildebrandt, T.; Ori, A.

10.1101/220343 — systems biology — Posted on 2018-03-15

1144 CDC20B is required for deuterosome-mediated centriole production in multiciliated cells

Revinski, D. R.; Zaragosi, L.-E.; Boutin, C.; Ruiz-Garcia, S.; Deprez, M.; Thome, V.; Rosnet, O.; Gay, A.-S.; Mercey, O.; Paquet, A.; Pons, N.; Ponzio, G.; Marcet, B.; Kodjabachian, L.; Barbry, P.

10.1101/218750 — cell biology — Posted on 2018-03-15

1145 Inert and seed-competent tau monomers suggest structural origins of aggregation

Mirbaha, H.; Chen, D.; Morozova, O. A.; Ruff, K. M.; Sharma, A.; Liu, X.; Pappu, R. V.; Colby, D. W.; Mirzaei, H.; Joachimiak, L. A.; Diamond, M. I.

10.1101/163394 — neuroscience — Posted on 2018-03-15

1146 Learning naturalistic temporal structure in the posterior medial network

Aly, M.; Chen, J.; Turk-Browne, N. B.; Hasson, U.

10.1101/196287 — neuroscience — Posted on 2018-03-15

1147 Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching

Wagner, A. S.; Politi, A. Z.; Ast, A.; Bravo-Rodriguez, K.; Baum, K.; Buntru, A.; Strempel, N. U.; Brusendorf, L.; Haenig, C.; Boeddrich, A.; Plassmann, S.; Klockmeier, K.; Ramirez-Anguita, J. M.; Sanchez-Garcia, E.; Wolf, J.; Wanker, E. E.

10.1101/195297 — biochemistry — Posted on 2018-03-15

1148 Functional Characterization of Enhancer Evolution in the Primate Lineage

Klein, J. C.; Keith, A.; Agarwal, V.; Durham, T.; Shendure, J.

10.1101/283168 — genomics — Posted on 2018-03-15

1149 Imputing missing distances in molecular phylogenetics

Xia, X.

10.1101/276345 — bioinformatics — Posted on 2018-03-15

1150 Epithelial control of colonisation by Streptococcus pneumoniae at the human mucosal surface

Weight, C. M.; Venturini, C.; Pojar, S.; Jochems, S.; Reine, J.; Nikolaou, E.; Solorzano, C.; Anderson, C.; Noursadeghi, M.; Brown, J. S.; Ferreira, D. M.; Heyderman, R. S.

10.1101/281576 — immunology — Posted on 2018-03-15

1151 The signaling lipid sphingosine 1-phosphate regulates mechanical pain

Hill, R. Z.; Hoffman, B. U.; Morita, T.; Campos, S. M.; Lumpkin, E. A.; Brem, R. B.; Bautista, D. M.

10.1101/236778 — neuroscience — Posted on 2018-03-15

1152 Sparse graphical models for functional connectivity networks: best methods and the autocorrelation issue

Zhu, Y.; Cribben, I.

10.1101/128488 — neuroscience — Posted on 2018-03-15

1153 Astrocytes integrate and drive neural activity

Deemyad, T.; Lüthi, J.; Spruston, N.

10.1101/282764 — neuroscience — Posted on 2018-03-15

1154 Increased susceptibility to intracellular bacteria and necrotic inflammation driven by a dysregulated macrophage response to TNF

Bhattacharya, B.; Chatterjee, S.; Berland, R.; Pichugin, A.; Gao, Y.; Ivanov, A.; Connor, J. H.; Yan, B.-S.; Kobzik, L.; Kramnik, I.

10.1101/238873 — immunology — Posted on 2018-03-15

1155 Embryonic gene transcription in the spiny mouse (Acomys cahirinus): an investigation into the embryonic genome activation.

Mamrot, J.; Gardner, D. K.; Temple-Smith, P.; Dickinson, H.

10.1101/280412 — genomics — Posted on 2018-03-15

1156 Best Practices for Benchmarking Germline Small Variant Calls in Human Genomes

Krusche, P.; Trigg, L.; Boutros, P. C.; Mason, C. E.; De La Vega, F. M.; Moore, B. L.; Gonzalez-Porta, M.; Eberle, M. A.; Tezak, Z.; Labadibi, S.; Truty, R.; Asimenos, G.; Funke, B.; Fleharty, M.; Salit, M.; Zook, J. M.; Global Alliance for Genomics and Health Benchmarking Team,

10.1101/270157 — genomics — Posted on 2018-03-15

1157 Spatial and Temporal Changes in Habitat Heterogeneity Promote Partition of Resources by Syntopic Small Mammals in a Midlatitude Temperate Forest

De la Cruz-Arguello, I. M.; Castro-Campillo, A.; Zavala-Hurtado, A.; Salame-Mendez, A.; Ramirez-Pulido, J.

10.1101/278390 — ecology — Posted on 2018-03-15

1158 4D imaging reveals stage dependent random and directed cell motion during somite morphogenesis

McColl, J.; Mok, G. F.; Lippert, A. H.; Ponjavic, A.; Muresan, L.; Munsterberg, A.

10.1101/280883 — developmental biology — Posted on 2018-03-15

1159 A conserved nuclear export complex coordinates transcripts for dopaminergic synaptogenesis and neuronal survival

Maeder, C. I.; Kim, J.-I.; Kaganovsky, K.; Shen, A.; Li, Q.; Li, Z.; Xu, X. Z. S.; Li, J. B.; Xiang, Y. K.; Ding, J. B.; Shen, K.

10.1101/282137 — neuroscience — Posted on 2018-03-15

1160 An eQTL landscape of kidney tissue in human nephrotic syndrome

10.1101/281162 — genomics — Posted on 2018-03-15

1161 Structural plasticity of CENP-A regulated by H4 influences cellular levels and kinetochore assembly

Malik, N.; Dantu, S. C.; Kombrabail, M.; Ghosh, S. K.; Krishnamoorthy, G.; Kumar, A.

10.1101/282863 — biophysics — Posted on 2018-03-15

1162 Topographic diversity of structural connectivity in schizophrenia

Ruan, H.; Luo, Q.; Palaniyappan, L.; Huang, C.-C.; Lo, C.-Y.; Liu, M.-E.; Yang, A. C.; Tsai, S.-J.; Lin, C.-P.; Feng, J.

10.1101/282145 — neuroscience — Posted on 2018-03-15

1163 Predicting three-dimensional genome organization with chromatin states

Qi, Y.; Zhang, B.

10.1101/282095 — biophysics — Posted on 2018-03-15

1164 TOG domain MT polymerases accelerate MT plus end growth via electrostatically-steered diffusion-to-capture and electrostatic templating of GTP-tubulin

Venables, N.; Bretschneider, T.; Cross, R. A.

10.1101/282897 — biophysics — Posted on 2018-03-15

1165 Putative rapid-acting antidepressant nitrous oxide ("laughing gas") evokes rebound emergence of slow EEG oscillations during which TrkB signaling is induced

Kohtala, S.; Theilmann, W.; Rosenholm, M.; Kiuru, P.; Uusitalo, S.; Järventausta, K.; Yli-Hankala, A.; Yli-Kauhaluoma, J.; Wigren, H.-K.; Rantamäki, T.

10.1101/282954 — pharmacology and toxicology — Posted on 2018-03-15

1166 Reversible inhibition of specific transcription factor-DNA interactions using CRISPR

Shariati, A.; Dominguez, A.; Wernig, M.; Qi, S.; Skotheim, J.

10.1101/282681 — molecular biology — Posted on 2018-03-15

1167 Evaluating Tumor Evolution via Genomic Profiling of Individual Tumor Spheroids in a Malignant Ascites from a Patient with Ovarian Cancer Using a Laser-aided Cell Isolation Technique

Kim, S.; Kim, S.; Kim, J.; Kim, B.; Kim, S. I.; Kim, M. A.; Kwon, S.; Song, Y. S.

10.1101/282277 — cancer biology — Posted on 2018-03-15

1168 Deactivation and Mislocalization of a kinase protein induced by a single amino acid mutation on the proton transport catalytic aspartic acid

Zhang, Y.

10.1101/282822 — biochemistry — Posted on 2018-03-15

1169 Arimoclomol as a potential therapy for neuronopathic Gaucher Disease

Kirkegaard, T.; Dardis, A.; Bembi, B.; Fog-Tonnesen, C. K.; Petersen, N. H. T.; Bornaes, C.; Solanko, L. M.; Magnoni, R.; Zago, P.; Malini, E.; Peruzzo, P.

10.1101/281824 — neuroscience — Posted on 2018-03-15

1170 Natural selection on plasticity of thermal traits in a highly seasonal environment

Bacigalupe, L. D.; Gaitan-Espitia, J. D.; Barria, A. M.; Gonzalez, A.; Ruiz-Aravena, M.; Trinder, M.; Sinervo, B.

10.1101/191825 — evolutionary biology — Posted on 2018-03-15

1171 Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases

Kaiser, F.; Bittrich, S.; Salentin, S.; Leberecht, C.; Haupt, V. J.; Krautwurst, S.; Schroeder, M.; Labudde, D.

10.1101/198846 — bioinformatics — Posted on 2018-03-15

1172 Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids

Di Rienzi, S. C.; Jacobson, J.; Kennedy, E. A.; Bell, M. E.; Shi, Q.; Waters, J. L.; Lawrence, P.; Brenna, J. T.; Britton, R. A.; Walter, J.; Ley, R. E.

10.1101/164715 — microbiology — Posted on 2018-03-15

1173 GIVE: toward portable genome browsers for personal websites

Cao, X.; Yan, Z.; Wu, Q.; Zheng, A.; Zhong, S.

10.1101/177832 — bioinformatics — Posted on 2018-03-15

1174 The landscape of somatic mutation in sporadic Chinese colorectal cancer

Liu, Z.; Yang, C.; Li, X.; Luo, W.; Roy, B.; Xiong, T.; Zhang, X.; Yang, H.; Wang, J.; Ye, Z.; Chen, Y.; Song, J.; Ma, S.; Zhou, Y.; Yang, M.; Fang, X.; Du, J.

10.1101/155671 — genomics — Posted on 2018-03-15

1175 Estimates of Introgression as a Function of Pairwise Distances

Pfeifer, B.; Kapan, D. D.

10.1101/154377 — evolutionary biology — Posted on 2018-03-15

1176 Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons

Zak, J. D.; Grimaud, J.; Li, R.-c.; Li, C.-c.; Murthy, V. N.

10.1101/282731 — neuroscience — Posted on 2018-03-15

1177 Acidic microenvironment shaped by lactate accumulation promotes pluripotency through multiple mechanisms

Guo, W.-T.; Wang, S.-H.; Zhang, X.-S.; Shi, M.; Hao, J.; Wang, X.-W.; Gu, K.-L.; Duan, F.-F.; Yan, Y.; Yang, X.; Zhang, C.; Liao, L.-Q.; Wang, Y.

10.1101/282475 — developmental biology — Posted on 2018-03-15

1178 Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling

Hong, S.-R.; Wang, C.-L.; Huang, Y.-S.; Chang, Y.-C.; Chang, Y.-C.; Pusapati, G. V.; Lin, C.-Y.; Hsu, N.; Cheng, H.-C.; Chiang, Y.-C.; Huang, W.-E.; Shaner, N. C.; Rohatgi, R.; Inoue, T.; Lin, Y.-C.

10.1101/282103 — cell biology — Posted on 2018-03-15

1179 Self-assembly of the RZZ complex into filaments drives kinetochore expansion in the absence of microtubule attachment

Gassmann, R.; Pereira, C.; Reis, R. M.; Gama, J. B.; Cheerambathur, D. K.; Carvalho, A. X.

10.1101/282707 — cell biology — Posted on 2018-03-15

1180 Structure of the receptor-activated human TRPC6 ion channel

Tang, Q.; Guo, W.; Zheng, L.; Wu, J.-X.; Liu, M.; Zhou, X.; Zhang, X.; Chen, L.

10.1101/282814 — biophysics — Posted on 2018-03-15

1181 ERASE: a novel surface reconditioning strategy for single-molecule experiments

Broadwater, D. W. B.; Altman, R. B.; Blanchard, S. C.; Kim, H. D.

10.1101/282632 — biophysics — Posted on 2018-03-15

1182 Structure of the mouse TRPC4 ion channel

Duan, J.; Li, J.; Bo, Z.; Chen, G.-L.; Peng, X.; Zhang, Y.; Wang, J.; Clapham, D. E.; Li, Z.; Zhang, J.

10.1101/282715 — biophysics — Posted on 2018-03-15

1183 Astrocytes integrate and drive neural activity

Deemyad, T.; Lüthi, J.; Spruston, N.

10.1101/282764 — neuroscience — Posted on 2018-03-15

1184 Avian thermoregulation in the heat: is evaporative cooling more economical in nocturnal birds?

O'Connor, R. S.; Smit, B.; Talbot, W. A.; Gerson, A. R.; Brigham, M.; Wolf, B. O.; McKechnie, A. E.

10.1101/282640 — physiology — Posted on 2018-03-14

1185 Electrical transient laws in neuronal microdomains based on electro-diffusion

Cartailler, J.; Holcman, D.

10.1101/282665 — neuroscience — Posted on 2018-03-14

1186 QTL mapping of natural variation reveals that the developmental regulator bruno reduces tolerance to P-element transposition in the Drosophila female germline

Kelleher, E.; Jaweria, J.; Akoma, U.; Ortega, L.; Tang, W.

10.1101/282541 — genetics — Posted on 2018-03-14

1187 Genetic dissection of assortative mating behavior

Merrill, R. M.; Rastas, P.; Melo, M.-C.; Barker, S.; Davey, J.; McMillan, W. O.; Jiggins, C.

10.1101/282301 — evolutionary biology — Posted on 2018-03-14

1188 EREFinder: Genome-wide detection of estrogen response elements

Anderson, A.; Jones, A.

10.1101/282533 — bioinformatics — Posted on 2018-03-14

1189 Quantifying the impact of public omics data

Perez-Riverol, Y.; Zorin, A.; Dass, G.; Glont, M.; Vizcaino, J. A.; Jarnuczak, A.; Petryszak, R.; Ping, P.; Hermjakob, H.

10.1101/282517 — bioinformatics — Posted on 2018-03-14

1190 Axons morphometry in the human spinal cord

Duval, T.; Saliani, A.; Nami, H.; Nanci, A.; Stikov, N.; Leblond, H.; Cohen-Adad, J.

10.1101/282434 — neuroscience — Posted on 2018-03-14

1191 Inter- and intra-specific genomic divergence in Drosophila montana shows evidence for cold adaptation

Parker, D. J.; Wiberg, R. A. W.; Trivedi, U.; Tyukmaeva, V. I.; Gharbi, K.; Butlin, R. K.; Hoikkala, A.; Kankare, M.; Ritchie, M. G.

10.1101/282582 — genomics — Posted on 2018-03-14

1192 Complex interaction of resource availability, life-history and demography determines the dynamics and stability of stage-structured populations

Tung, S.; Rajamani, M.; Joshi, A.; Dey, S.

10.1101/138446 — ecology — Posted on 2018-03-14

1193 Contrasting patterns of coding and flanking region evolution in mammalian keratin associated protein-1 genes

Zhou, H.; Visnovska, T.; Gong, H.; Schmeier, S.; Hickford, J.; Ganley, A. R. D.

10.1101/282418 — genetics — Posted on 2018-03-14

1194 Temporal Control of Transcription by Zelda in living Drosophila embryos

Dufourt, J.; Trullo, A.; Hunter, J.; Fernandez, C.; Lazaro, J.; Dejean, M.; Morales, L.; Schulz, K. N.; Harrison, M. M.; Radulescu, O.; Favard, C.; Lagha, M.

10.1101/282426 — developmental biology — Posted on 2018-03-14

1195 smCounter2: an accurate low-frequency variant caller for targeted sequencing data with unique molecular identifiers

Xu, C.; Gu, X.; Padmanabhan, R.; Wu, Z.; Peng, Q.; DiCarlo, J.; Wang, Y.

10.1101/281659 — bioinformatics — Posted on 2018-03-14

1196 In vitro and in vivo phasor analysis of stoichiometry and pharmacokinetics using near-infrared dyes

Chen, S.-J. K.; Sinsuebphon, N.; Rudkouskaya, A.; Barroso, M.; Intes, X.; Michalet, X.

10.1101/212977 — bioengineering — Posted on 2018-03-14

1197 Site-Specific Labelling of Multidomain Proteins by Amber Codon Suppression

Heil, C. S.; Rittner, A.; Goebel, B.; Beyer, D.; Grininger, M.

10.1101/282525 — biochemistry — Posted on 2018-03-14

1198 Automated sequential chromogenic IHC double staining with two HRP substrates.

Petersen, K. H.; Lohse, J.; Ramsgaard, L.

10.1101/276501 — pathology — Posted on 2018-03-14

1199 An Open-source Tool for Analysis and Automatic Identification of Dendritic Spines Using Machine Learning

Smirnov, M. S.; Garrett, T. R.; Yasuda, R.

10.1101/281667 — neuroscience — Posted on 2018-03-14

1200 Predicting three-dimensional genome organization with chromatin states

Qi, Y.; Zhang, B.

10.1101/282095 — biophysics — Posted on 2018-03-14

1201 Clusters of fatty acids in the serum triacylglyceride fraction associate with the disorders of type 2 diabetes

Johnston, L.; Liu, Z.; Retnakaran, R.; Zinman, B.; Giacca, A.; Harris, S. B.; Bazinet, R. P.; Hanley, A. J.

10.1101/279703 — epidemiology — Posted on 2018-03-14

1202 Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment

Sliz, E.; Kettunen, J.; Holmes, M. V.; Oliver-Williams, C.; Boachie, C.; Wang, Q.; Mannikko, M.; Sebert, S.; Walters, R.; Lin, K.; Millwood, I. Y.; Clarke, R.; Lee, L.; Rankin, N.; Welsh, P.; Delles, C.; Ford, I.; Jukema, J. W.; Trompet, S.; Perola, M.; Salomaa, V.; Jarvelin, M.-R.; Chen, Z.; Lawlor, D. A.; Ala-Korpela, M.; Danesh, J.; Davey Smith, G.; Sattar, N.; Butterworth, A.; Wurtz, P.

10.1101/278861 — epidemiology — Posted on 2018-03-14

1203 Meta-microRNAs as potential noninvasive markers for early diagnosis of Alzheimer’s disease

Jiang, N.; Ruan, C.-J.; Cheng, X.-R.; Wang, L.-N.; Tan, J.-P.; Wang, W.-S.; Liu, F.; Zhou, W.-X.; Zhang, Y.-X.

10.1101/281915 — neuroscience — Posted on 2018-03-14

1204 Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis

Poetsch, A. R.; Boulton, S. J.; Luscombe, N.

10.1101/168153 — genomics — Posted on 2018-03-14

1205 Histone H3 T11 phosphorylation by Sch9 and CK2 regulates lifespan by controlling the nutritional stress response

Workman, J. L.; Oh, S.; Gogol, M. M.; Suganuma, T.

10.1101/282384 — genetics — Posted on 2018-03-14

1206 Mixed Effects Association of Single Cells Identifies an Expanded Th1-Skewed Cytotoxic Effector CD4+ T Cell Subset in Rheumatoid Arthritis

Fonseka, C. Y.; Rao, D. A.; Teslovich, N. C.; Hannes, S. K.; Slowikowski, K.; Gurish, M. F.; Donlin, L. T.; Weinblatt, M. E.; Massarotti, E. M.; Coblyn, J. S.; Helfgott, S. M.; Todd, D. J.; Bykerk, V. P.; Karlson, E. W.; Ermann, J.; Lee, Y. C.; Brenner, M. B.; Raychaudhuri, S.

10.1101/172403 — bioinformatics — Posted on 2018-03-14

1207 Transcriptome analysis in whole blood reveals increased microbial 1 diversity in schizophrenia

M Olde Loohuis, L.; Mangul, S.; Ori, A.; Jospin, G.; Koslicki, D.; Yang, H. T.; Wu, T.; Boks, M. P.; Lomen-Hoerth, C.; Wiedau-Pazos, M.; Cantor, R.; M de Vos, W.; S Kahn, R.; Eskin, E.; Ophoff, R. A.

10.1101/057570 — microbiology — Posted on 2018-03-14

1208 Comprehensive pathway analyses of schizophrenia risk loci point to dysfunctional postsynaptic signaling

Schijven, D.; Kofink, D.; Tragante, V.; Verkerke, M.; Pulit, S. L.; Kahn, R. S.; Veldink, J. H.; Vinkers, C. H.; Boks, M. P.; Luykx, J. J.

10.1101/117481 — genetics — Posted on 2018-03-14

1209 Identity-by-descent analyses for measuring population dynamics and selection in recombining pathogens

Henden, L.; Lee, S.; Mueller, I.; Barry, A.; Bahlo, M.

10.1101/088039 — bioinformatics — Posted on 2018-03-14

1210 GetOrganelle: a simple and fast pipeline for de novo assembly of a complete circular chloroplast genome using genome skimming data

Jin, J.-J.; Yu, W.-B.; Yang, J.-B.; Song, Y.; Yi, T.-S.; Li, D.-Z.

10.1101/256479 — bioinformatics — Posted on 2018-03-14

1211 Quantifying the unquantifiable: why Hymenoptera -- not Coleoptera -- is the most speciose animal order

Forbes, A. A.; Bagley, R. K.; Beer, M. A.; Hippee, A. C.; Widmayer, H. A.

10.1101/274431 — zoology — Posted on 2018-03-14

1212 A Computational Synaptic Antibody Characterization and Screening Framework for Array Tomography

Simhal, A. K.; Gong, B.; Trimmer, J. S.; Weinberg, R. J.; Smith, S. J.; Sapiro, G.; Micheva, K. D.

10.1101/258756 — neuroscience — Posted on 2018-03-14

1213 Impulsive choice in mice lacking paternal expression of Grb10 provides evidence for intra-genomic conflict in behavior

Dent, C. L.; Humby, T.; Swaden Lewis, K.; Ward, A.; Fischer-Colbrie, R.; Wilkinson, L.; Wilkins, J.; Isles, A.

10.1101/281873 — genetics — Posted on 2018-03-14

1214 TFAP2 transcription factors are regulators of lipid droplet biogenesis

Scott, C. C.; Vossio, S.; Rougemont, J.; Gruenberg, J.

10.1101/282376 — cell biology — Posted on 2018-03-14

1215 Binding Affinity Regression Models from Repeats Mutation in Polyglutamine Disease

Rajendran, A.; VijayaKumar, V.

10.1101/281949 — systems biology — Posted on 2018-03-14

1216 DevoWorm: data-theoretical synthesis of C. elegansdevelopment.

Alicea, B. J.; Gordon, R.; Portegys, T. E.

10.1101/282004 — systems biology — Posted on 2018-03-14

1217 Efficient CRISPR/Cas9-based genome editing and its application to conditional genetic analysis in Marchantia polymorpha

Sugano, S. S.; Nishihama, R.; Shirakawa, M.; Takagi, J.; Matsuda, Y.; Ishida, S.; Shimada, T.; Hara-Nishimura, I.; Osakabe, K.; Kohchi, T.

10.1101/277350 — plant biology — Posted on 2018-03-14

1218 A widespread decrease of chromatin accessibility in age-related macular degeneration

WANG, J.; Zibetti, C.; Shang, P.; Sripathi, S. R.; Zhang, P.; Cano, M.; Hoang, T.; Xia, S.; Ji, H.; Merbs, S. L.; Zack, D. J.; Handa, J. T.; Sinha, D.; Blackshaw, S.; Qian, J.

10.1101/264564 — genomics — Posted on 2018-03-14

1219 Widespread transcriptional scanning in testes modulates gene evolution rates

Xia, B.; Baron, M.; Yan, Y.; Wagner, F.; Kim, S. Y.; Keefe, D. L.; Alukal, J. P.; Boeke, J. D.; Yanai, I.

10.1101/282129 — evolutionary biology — Posted on 2018-03-14

1220 New tools for the analysis and validation of Cryo-EM maps and atomic models

Afonine, P. V.; Klaholz, B. P.; Moriarty, N. W.; Poon, B. K.; Sobolev, O. V.; Terwilliger, T. C.; Adams, P. D.; Urzhumtsev, A.

10.1101/279844 — bioinformatics — Posted on 2018-03-14

1221 Measuring Endoplasmic Reticulum Signal Sequences Translocation Efficiency Using the Xbp1 Arrest Peptide

Kriegler, T.; Magoulopoulou, A.; Amate Marchal, R.; Hessa, T.

10.1101/281535 — biochemistry — Posted on 2018-03-14

1222 Novel role of Lin28 signaling in regulation of mammalian PNS and CNS axon regeneration

Wang, X.-W.; Liu, C.-M.; Hall, P. A.; Jiang, J.-J.; Katchis, C. D.; Kang, S.; Dong, B. C.; Li, S.; Zhou, F.-Q.

10.1101/281725 — neuroscience — Posted on 2018-03-14

1223 A conserved nuclear export complex coordinates transcripts for dopaminergic synaptogenesis and neuronal surviva

Maeder, C. I.; Kim, J.-I.; Kaganovsky, K.; Shen, A.; Li, Q.; Li, Z.; Xu, X. Z. S.; Li, J. B.; Xiang, Y. K.; Ding, J. B.; Shen, K.

10.1101/282137 — neuroscience — Posted on 2018-03-14

1224 Topographic diversity of structural connectivity in schizophrenia

Ruan, H.; Luo, Q.; Palaniyappan, L.; Huang, C.-C.; Lo, C.-Y.; Liu, M.-E.; Yang, A. C.; Tsai, S.-J.; Lin, C.-P.; Feng, J.

10.1101/282145 — neuroscience — Posted on 2018-03-14

1225 Estimation of population divergence times from SNP data and a test for treeness

Theunert, C.; Slatkin, M.

10.1101/281881 — genomics — Posted on 2018-03-14

1226 Single cell transcriptomics reveals molecular subtype and functional heterogeneity in models of breast cancer

Roden, D. L.; Baker, L. A.; Elsworth, B.; Chan, C.-L.; Harvey, K.; Deng, N.; Wu, S.; Cazet, A.; Nair, R.; Swarbrick, A.

10.1101/282079 — cancer biology — Posted on 2018-03-14

1227 Testing an Optimally Weighted Combination of Common and/or Rare Variants with Multiple Traits

Wang, Z.; Sha, Q.; Zhang, K.; Zhang, S.

10.1101/281832 — bioinformatics — Posted on 2018-03-14

1228 Hydrodynamic cavitation as an energy efficient process to increase biochar surface area and porosity: a case study

Albanese, L.; Baronti, S.; Liguori, F.; Meneguzzo, F.; Barbaro, P.; Vaccari, F. P.

10.1101/280685 — bioengineering — Posted on 2018-03-14

1229 idtracker.ai: Tracking all individuals in large collectives of unmarked animals

Romero Ferrero, F.; bergomi, m. g.; Hinz, R.; Hernandez Heras, F. J.; de Polavieja, G.

10.1101/280735 — animal behavior and cognition — Posted on 2018-03-14

1230 Automated high-quality reconstruction of metabolic networks from high-throughput data

Hartleb, D.; Fritzemeier, C. J.; Lercher, M.

10.1101/282251 — systems biology — Posted on 2018-03-14

1231 Different alleles of the same gene vary in pleiotropy, often mediated through currency metabolite production

Alzoubi, D.; Desouki, A. A.; Lercher, M.

10.1101/144329 — systems biology — Posted on 2018-03-14

1232 Topographic effects on dispersal patterns of Phytophthora cinnamomi at a stand scale in a Spanish heathland

Cardillo, E.; Abad, E.; Acedo, A.

10.1101/281691 — plant biology — Posted on 2018-03-14

1233 Multimodal modeling of neural network activity: computing LFP, ECoG, EEG and MEG signals with LFPy2.0

Hagen, E.; Naess, S.; Ness, T. V.; Einevoll, G. T.

10.1101/281717 — neuroscience — Posted on 2018-03-14

1234 Heterosynaptic Plasticity Normalizes Cortical Excitatory-Inhibitory Balance

Field, R.; D'amour, J.; Tremblay, R.; Rudy, B.; Froemke, R.

10.1101/282012 — neuroscience — Posted on 2018-03-14

1235 Prosody perception in children: studying individual differences with novel brain and behavioral approaches

Myers, B.; Vaughan, C.; Soman, U.; Blain, S.; Korsnack, K.; Camarata, S.; Gordon, R.

10.1101/281998 — neuroscience — Posted on 2018-03-14

1236 Identifying G protein-coupled receptor dimers from crystal packings

Stenkamp, R. E.

10.1101/282178 — biophysics — Posted on 2018-03-14

1237 A Bayesian Mixture Modelling Approach For Spatial Proteomics

Crook, O. M.; Mulvey, C. M.; Kirk, P. D. W.; Lilley, K. S.; Gatto, L.

10.1101/282269 — systems biology — Posted on 2018-03-14

1238 Disentangling locus of perceptual learning in the visual hierarchy of motion processing

Zhang, R.; Tadin, D.

10.1101/282319 — neuroscience — Posted on 2018-03-14

1239 Covert spatial selection in primate basal ganglia

Arcizet, F.; Krauzlis, R.

10.1101/282236 — neuroscience — Posted on 2018-03-14

1240 3D grid cells in human entorhinal cortex: Theoretical and methodological considerations and fMRI findings

Kim, M.; Maguire, E. A.

10.1101/282327 — neuroscience — Posted on 2018-03-14

1241 Analysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene generated using CRISPR-Cas9 RNPs

Turner, A. N.; Andersen, R. S.; Bookout, I. E.; Brashear, L. N.; Davis, J. C.; Gahan, D. M.; Gotham, J. P.; Hijaz, B. A.; Kaushik, A. S.; McGill, J. B.; Miller, V. L.; Moseley, Z. P.; Nowell, C. L.; Patel, R. K.; Rodgers, M. C.; Shihab, Y. A.; Walker, A. P.; Glover, S. R.; Foster, S. D.; Challa, A. K.

10.1101/277715 — genetics — Posted on 2018-03-14

1242 Functional analysis of a hypomorphic allele shows that MMP14 catalytic activity is the prime determinant of the Winchester syndrome phenotype

de Vos, I. J. H. M.; Tao, E. Y.; Ong, S. L. M.; Goggi, J. L.; Scerri, T.; Wilson, G. R.; Low, C. G. M.; Wong, A. S. W.; Grussu, D.; Stegmann, A. P. A.; van Geel, M.; Janssen, R.; Amor, D. J.; Bahlo, M.; Dunn, N. R.; Carney, T. J.; Lockhart, P. J.; Coull, B. J.; van Steensel, M. A. M.

10.1101/281485 — genetics — Posted on 2018-03-14

1243 Adaptive landscape of protein variation in human exomes

Patel, R.; Sanderford, M. D.; Lanham, T. R.; Tamura, K.; Platt, A.; Gilksberg, B. S.; Dudley, J. T.; Scheinfeldt, L. B.; Xu, K.; Kumar, S.

10.1101/282152 — evolutionary biology — Posted on 2018-03-14

1244 The mitochondrial genomes of the mesozoans Intoshia linei, Dicyema sp., and Dicyema japonicum

Robertson, H.; Schiffer, P.; Telford, M.

10.1101/282285 — evolutionary biology — Posted on 2018-03-14

1245 Weighted trait-abundance early warning signals better predict population collapse

Clements, C.; van de Pol, M.; Ozgul, A.

10.1101/282087 — ecology — Posted on 2018-03-14

1246 Conformational flexibility of collagen molecules: composition and environmental effects

Rezaei, N.; Lyons, A.; Forde, N. R.

10.1101/279380 — biophysics — Posted on 2018-03-14

1247 Protein-Protein Interaction Network Analysis and Identification of Key Players in nor-NOHA and NOHA Mediated Pathways for Treatment of Cancer through Arginase Inhibition: Insights from Systems Biology

Ahammad, I.

10.1101/281030 — systems biology — Posted on 2018-03-14

1248 Mosaic patterns of B-vitamin synthesis and utilization in a natural marine microbial community

Gomez-Consarnau, L.; Sachdeva, R.; Gifford, S. M.; Cutter, L. S.; Fuhrman, J.; Sanudo-Wilhelmy, S. A.; Moran, M. A.

10.1101/280438 — microbiology — Posted on 2018-03-14

1249 Assessing macrophyte seasonal dynamics using dense time series of medium resolution satellite data

Villa, P.; Pinardi, M.; Bolpagni, R.; Gillier, J.-M.; Zinke, P.; Nedelcut, F.; Bresciani, M.

10.1101/279448 — ecology — Posted on 2018-03-14

1250 Synaptic plasticity onto inhibitory neurons as a mechanism for ocular dominance plasticity.

Bono, J.; Clopath, C.

10.1101/280511 — neuroscience — Posted on 2018-03-14

1251 A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress.

Acharya, B. R.; Nestor-Bergmann, A.; Liang, X.; Budnar, S.; Jensen, O. E.; Bryant, Z.; Yap, A. S.

10.1101/281154 — cell biology — Posted on 2018-03-14

1252 WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death

Wan, H.; Wang, Q.; Chen, X.; Zeng, Q.; Shao, Y.; Fang, H.; Liao, X.; Li, H.; Liu, M.; Xu, T.-L.; Li, D.; Liu, M.; Meng, B.; Tang, B.; Zhang, Z.; Liao, L.

10.1101/282210 — cell biology — Posted on 2018-03-14

1253 A novel role for the HLH protein Inhibitor of Differentiation 4 (ID4) in the DNA damage response in basal-like breast cancer.

Baker, L. A.; Krisp, C.; Roden, D.; Holliday, H.; Wu, S. Z.; Junankar, S.; Serandour, A. A.; Mohammed, H.; Nair, R.; Chan, C.-L.; Yang, J.; Foreman, N.; Fitzpatrick, B.; Sankaranarayanan, G.; Law, A. M.; Ormandy, C.; Naylor, M. J.; McFarland, A.; Simpson, P. T.; Lakhani, S.; O'Toole, S.; Selinger, C.; Anderson, L.; Samimi, G.; Hacker, N. F.; Kaplan, W.; Carroll, J. S.; Molloy, M.; Swarbrick, A.

10.1101/281196 — cancer biology — Posted on 2018-03-14

1254 Spatial and ontogenetic variation in susceptibility to polarotactic ecological traps

Villalobos-Jimenez, G.; Meah, R.; Hassall, C.

10.1101/282046 — evolutionary biology — Posted on 2018-03-14

1255 A sexually dimorphic neuroendocrine cascade acts through shared sensory neurons to regulate behavior in C. elegans

Hilbert, Z. A.; Kim, D. H.

10.1101/281741 — neuroscience — Posted on 2018-03-14

1256 CREBBP and WDR 24 Affects Quantitative Variation in Red Colouration in the Chicken

Fogelholm, J.; Henriksen, R.; Höglund, A.; Huq, N.; Johnsson, M.; Lenz, R.; Jensen, P.; Wright, D.

10.1101/281840 — genetics — Posted on 2018-03-14

1257 Evolution analysis and expression divergence of the chitinase gene family against Leptosphaeria maculans and Sclerotinia sclerotiorum infection in Brassica napus

Xu, W.; Zhou, T.; An, B.; Xu, B.; Li, G.

10.1101/281923 — plant biology — Posted on 2018-03-14

1258 Arsenite exposure inhibits histone acetyltransferase p300 for attenuating H3K27ac at enhancers in low-dose exposed mouse embryonic fibroblast cells

Zhu, Y.; Li, Y.; Lou, D.; Gao, Y.; Yu, J.; Kong, D.; Zhang, Q.; Jia, Y.; Zhang, H.; Wang, Z.

10.1101/278424 — pharmacology and toxicology — Posted on 2018-03-14

1259 De novo assembly, characterization, functional annotation and expression patterns of the black tiger shrimp (Penaeus monodon) transcriptome

Huerlimann, R.; Wade, N. M.; Gordon, L.; Montenegro, J. D.; Goodall, J.; McWilliam, S.; Tinning, M.; Siemering, K.; Giardina, E.; Donovan, D.; Sellars, M. J.; Cowley, J. A.; Condon, K.; Coman, G. J.; Khatkar, M. S.; Raadsma, H. W.; Maes, G.; Zenger, K. R.; Jerry, D. R.

10.1101/280420 — molecular biology — Posted on 2018-03-14

1260 Complex Structural Variants Resolved by Short-Read and Long-Read Whole Genome Sequencing in Mendelian Disorders

Sanchis-Juan, A.; Stephens, J.; French, C. E.; Gleadall, N.; Megy, K.; Penkett, C.; Stirrups, K.; Delon, I.; Dewhurst, E.; Dolling, H.; Erwood, M.; Grozeva, D.; Arno, G.; Webster, A. R.; Cole, T.; Austin, T.; Garcia Branco, R.; NIHR BioResource, N. B.; Ouwehand, W. H.; Raymond, F. L.; Carss, K. J.

10.1101/281683 — genomics — Posted on 2018-03-14

1261 An eQTL landscape of kidney tissue in human nephrotic syndrome

Gillies, C. E.; Putler, R.; Menon, R.; Otto, E.; Yasutake, K.; Nair, V.; Fermin, D.; Eddy, S.; Vega-Warner, V.; Nephrotic Syndrome Study Network, ; Hacohen, N.; Wen, X.; Kretzler, M.; Sampson, M.

10.1101/281162 — genomics — Posted on 2018-03-14

1262 Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

Barbu, M. C.; Zeng, Y.; Shen, X.; Cox, S.; Clarke, T.; Gibson, J.; Adams, M. J.; Johnstone, M.; Haley, C. S.; Lawrie, S. M.; Deary, I. J.; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; 23andMe Research Team, ; McIntosh, A. M.; Whalley, H. C.

10.1101/282053 — genetics — Posted on 2018-03-14

1263 Characterising the microbiome from host shotgun sequencing data: bacterial and diatom community dynamics derived from killer whale skin

Hooper, R.; Brealey, J.; van der Valk, T.; Alberdi, A.; Durban, J. W.; Fearnbach, H.; Robertson, K. M.; Baird, R. W.; Hanson, M. B.; Wade, P.; Gilbert, M. T. P.; Morin, P. A.; Wolf, J. B. W.; Foote, A. D.; Guschanski, K.

10.1101/282038 — evolutionary biology — Posted on 2018-03-14

1264 Electron cryo-microscopy structure of the canonical TRPC4 ion channel

Vinayagam, D.; Mager, T.; Apelbaum, A.; Bothe, A.; Merino, F.; Hofnagel, O.; Gatsogiannis, C.; Raunser, S.

10.1101/280503 — biochemistry — Posted on 2018-03-14

1265 Cryopreservation of human mucosal tissues

Hughes, S. M.; Ferre, A. L.; Yandura, S. E.; Shetler, C.; Baker, C. A. R.; Calienes, F.; Levy, C. N.; Astronomo, R. D.; Shu, Z.; Lentz, G. M.; Fialkow, M.; Kirby, A. C.; McElrath, M. J.; Sinclair, E.; Rohan, L. C.; Anderson, P. L.; Shacklett, B. L.; Dezzutti, C. S.; Gao, D.; Hladik, F.

10.1101/262519 — immunology — Posted on 2018-03-14

1266 Changes in Acceptance of Evolution and Associated Factors during a Year of Introductory Biology: The Shifting Impacts of Biology Knowledge, Politics, Religion, Demographics, and Understandings of the Nature of Science

Dunk, R. D. P.; Wiles, J. R.

10.1101/280479 — scientific communication and education — Posted on 2018-03-13

1267 PKD2 influence uric acid levels and gout risk by interacting with ABCG2

Dong, Z.; Zhou, J.; Jiang, S.; Li, Y.; Zhao, D.; Yang, C.; Ma, Y.; He, H.; Ji, H.; Jin, L.; Zou, H.; Wang, J.

10.1101/278713 — genetics — Posted on 2018-03-13

1268 Ordino: visual analysis tool for ranking and exploring genes, cell lines, and tissue samples

Streit, M.; Gratzl, S.; Stitz, H.; Wernitznig, A.; Zichner, T.; Haslinger, C.

10.1101/277848 — bioinformatics — Posted on 2018-03-13

1269 Ancient DNA analysis of food remains in human dental calculus from the Edo period, Japan

Sawafuji, R.; Saso, A.; Suda, W.; Hattori, M.; Ueda, S.

10.1101/246868 — molecular biology — Posted on 2018-03-13

1270 MiR-505-3p, a New Repressor of Puberty Onset in Female Mice

Tong, L.; Wang, M.; Zhou, Y.; Li, Y.; Chen, L.; Xu, F.; Li, K.; Xiao, J.

10.1101/271718 — genetics — Posted on 2018-03-13

1271 High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays

Chung, J. E.; Joo, H. R.; Fan, J. L.; Liu, D. F.; Barnett, A. H.; Chen, S.; Geaghan-Breiner, C.; Karlsson, M. P.; Karlsson, M.; Lee, K. Y.; Liang, H.; Magland, J. F.; Mehaffey, W. H.; Tooker, A. C.; Brainard, M. S.; Greengard, L. F.; Tolosa, V. M.; Frank, L. M.

10.1101/242693 — neuroscience — Posted on 2018-03-13

1272 Control of non-homeostatic feeding in sated mice using associative learning of contextual food cues

Stern, S. A.; Doerig, K. R.; Azevedo, E. P.; Stoffel, E.; Friedman, J. M.

10.1101/247825 — neuroscience — Posted on 2018-03-13

1273 Uterine progesterone signaling is a target for metformin therapy in PCOS-like rats

Hu, M.; Zhang, Y.; Feng, J.; Xu, X.; Zhang, J.; Zhao, W.; Guo, X.; Li, J.; Vestin, E.; Cui, P.; Li, X.; Wu, X.-k.; Brannstrom, M.; Shao, L. R.; Billig, H.

10.1101/238261 — physiology — Posted on 2018-03-13

1274 Mid-Infrared Spectroscopy Study of Effects of Neonicotinoids on Forager Honey Bee (Apis mellifera) Fat Bodies and Their Connection to Colony Collapse Disorder

Feng, Y.; Luthra, A.; Ding, K.; Yang, Y.; Savage, J.; Wei, X.; Moeschter, R.; Ahuja, S.; Villegas, V.; Torbina, B.; Ahooja, A.; Ellis, T.; Boechler, A.-M.; Roberts, A.

10.1101/205112 — pharmacology and toxicology — Posted on 2018-03-13

1275 A network of MAP-Kinase pathways and transcription factors regulates cell-to-cell communication and cell wall integrity in Neurospora crassa

Glass, N. L.; Fischer, M. S.; Wu, V. W.; Lee, J. E.; O'Malley, R. C.

10.1101/281931 — genetics — Posted on 2018-03-13

1276 Population genetics of Paramecium mitochondrial genomes: recombination, mutation spectrum, and efficacy of selection.

Johri, P.; Marinov, G.; Doak, T. G.; Lynch, M.

10.1101/281865 — evolutionary biology — Posted on 2018-03-13

1277 Human Puf-A, a Novel Component of 90S Pre-ribosome, Links Ribosome Biogenesis to Cancer Progression

Yu, J.; Cho, H.-C.; Huang, Y.; Hung, J.-T.; Lai, L.-C.; Wang, S.-H.; Liu, Y.-H.; Cho, I.-M.; Kuo, M.-W.; Cheng, P.-Y.; Ho, M.-Y.; Lin, R.-J.; Yu, A. L.

10.1101/281857 — cancer biology — Posted on 2018-03-13

1278 Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact

Ray, T. A.; Roy, S.; Kozlowski, C.; Wang, J.; Cafaro, J.; Hulbert, S.; Wright, C. V. E.; Field, G. D.; Kay, J. N.

10.1101/235978 — neuroscience — Posted on 2018-03-13

1279 Division of labor during biofilm matrix production

Dragos, A.; Kiesewalter, H. T.; Martin, M.; Hsu, C.-Y.; Hartmann, R.; Wechsler, T.; Eriksen, C.; Brix Pedersen, S.; Drescher, K.; Stanley-Wall, N.; Kummerli, R.; Kovacs, A. T.

10.1101/237230 — microbiology — Posted on 2018-03-13

1280 The Dynamics and Energy Landscape of DNA Plectoneme Nucleation

Walker, P. U.; Vanderlinden, W.; Lipfert, J.

10.1101/280719 — biophysics — Posted on 2018-03-13

1281 Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

Burns, M. B.; Montassier, E.; Abrahante, J.; Priya, S.; Niccum, D. E.; Khoruts, A.; Starr, T. K.; Knights, D.; Blekhman, R.

10.1101/090795 — cancer biology — Posted on 2018-03-13

1282 Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

Thodberg, M.; Thieffry, A.; Bornholdt, J.; Boyd, M.; Holmberg, C.; Azad, A.; Chen, Y.; Ekwall, K.; Nielsen, O.; Sandelin, A.

10.1101/281642 — genomics — Posted on 2018-03-13

1283 Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes

Altaner, C.; Altanerova, U.; Jakubechova, J.; Benejova, K.; Priscakova, P.; Pesta, M.; Pitule, P.; Topolcan, O.; Kausitz, J.; Zduriencikova, M.; Repiska, V.

10.1101/281808 — cancer biology — Posted on 2018-03-13

1284 Escher-FBA: A web application for interactive flux balance analysis

Rowe, E. G.; Palsson, B. O.; King, Z. A.

10.1101/281600 — bioengineering — Posted on 2018-03-13

1285 Unraveling rice tolerance mechanisms against Schizotetranychus oryzae mite infestation

Buffon, G.; Blasi, E.; Rativa, A.; Lamb, T.; Gastmann, R.; Adamski, J.; Schwambach, J.; Ricachenevsky, F.; Heringer, A.; Silveira, V.; Lopes, M.; Sperotto, R.

10.1101/281733 — plant biology — Posted on 2018-03-13

1286 Generation Of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited By TRPV1 Agonists

Guimaraes, M. Z. P.; De Vecchi, R.; Vitoria, G.; Sochacki, J. K.; Paulsen, B.; Lima, I.; da Silva, F. R.; da Costa, R. F. M.; Breton, L.; Rehen, S. K.

10.1101/281675 — neuroscience — Posted on 2018-03-13

1287 All-optical electrophysiology reveals brain-state dependent changes in hippocampal subthreshold dynamics and excitability

Adam, Y.; Kim, J. J.; Lou, S.; Zhao, Y.; Brinks, D.; Wu, H.; Mostajo-Radji, M. A.; Kheifets, S.; Parot, V.; Chettih, S.; Williams, K. J.; Farhi, S. L.; Madisen, L.; Harvey, C. D.; Zeng, H.; Arlotta, P.; Campbell, R. E.; Cohen, A. E.

10.1101/281618 — neuroscience — Posted on 2018-03-13

1288 Dectin-3 recognizes cryptococcal glucuronoxylomannan to initiate host defense against cryptococcosis

Huang, H.-R.; Li, F.; Han, H.; Lv, Q.-Z.; Xu, X.; Li, N.; Wang, S.; Xu, J.-F.; Jia, X.-M.

10.1101/281790 — immunology — Posted on 2018-03-13

1289 Exposing flaws in S-LDSC; reply to Gazal et al.

Speed, D.; Balding, D.

10.1101/280784 — genetics — Posted on 2018-03-13

1290 Timing of ESCRT-III protein recruitment and membrane scission during HIV-1 assembly

Johnson, D. S.; Bleck, M.; Simon, S. M.

10.1101/281774 — cell biology — Posted on 2018-03-13

1291 Pan-cancer deconvolution of cellular composition identifies molecular correlates of antitumour immunity and checkpoint blockade response

Chakravarthy, A.; Furness, A.; Joshi, K.; Ghorani, E.; Ford, K.; Ward, M. J.; King, E. V.; Lechner, M.; Marafioti, T.; Quezada, S.; Thomas, G. J.; Feber, A.; Fenton, T.

10.1101/281592 — cancer biology — Posted on 2018-03-13

1292 Tempo, mode, and fitness effects of mutation in Caenorhabditis elegans over 400 generations of minimal selection

Saxena, A. S.; Salomon, M. P.; Matsuba, C.; Yeh, S.-D.; Baer, C. F.

10.1101/280826 — evolutionary biology — Posted on 2018-03-13

1293 Simultaneous B and T cell acute lymphoblastic leukemias in zebrafish driven by transgenic MYC: implications for oncogenesis and lymphopoiesis

Borga, C.; Park, G.; Foster, C.; Burroughs-Garcia, J.; Marchesin, M.; Ahmed, S. T.; Bresolin, S.; Batchelor, L.; Scordino, T.; Miles, R. R.; te Kronnie, G.; Regens, J. L.; Frazer, J. K.

10.1101/281469 — cancer biology — Posted on 2018-03-13

1294 Model-based analysis of the stiffness of the wrist joint in active and passive conditions

Zonnino, A.; Sergi, F.

10.1101/281204 — bioengineering — Posted on 2018-03-13

1295 Detection of race-specific resistance against Puccinia coronata f. sp. avenae in Brachypodium species

Omidvar, V.; Dugyala, S.; Li, F.; Rottschaefer, S.; Miller, M.; Ayliffe, M.; Moscou, M.; Kianian, S.; Figueroa, M.

10.1101/281568 — pathology — Posted on 2018-03-13

1296 Acute and chronic toxicity assessment of benzylpenicillin G residues in heat-treated animal food products

Cui, C.; Zhang, X.; Wang, Y.; Lu, S.; Lu, H.; Hui, Q.; Ahmad, W.; Cai, Y.; Liu, X.; Liu, L.; Shi, F.; Liu, Y.; Zhao, K.; Zhai, F.; Xiang, Y.; Hu, P.; Li, Y.; Ren, H.; Jin, N.; Liu, Z.

10.1101/191346 — pharmacology and toxicology — Posted on 2018-03-13

1297 Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses

Helassa, N.; Durst, C.; Coates, C.; Kerruth, S.; Arif, U.; Schulze, C.; Wiegert, J. S.; Geeves, M.; Oertner, T.; Torok, K.

10.1101/233494 — neuroscience — Posted on 2018-03-13

1298 Evolutionary analysis implicates RNA polymerase II pausing and chromatin structure in nematode piRNA biogenesis

Beltran, T.; Barruso, C.; Birkle, T.; Stevens, L.; Schwartz, H. T.; Sternberg, P.; Fradin, H.; Gunsalus, K.; Piano, F.; Martinez-Perez, E.; Blaxter, M.; Sarkies, P.

10.1101/281360 — genomics — Posted on 2018-03-13

1299 Bicoid gradient formation mechanism and dynamics revealed by protein lifetime analysis

Durrieu, L.; Kirrmaier, D.; Schneidt, T.; Kats, I.; Raghavan, S.; Knop, M.; Saunders, T. E.; Hufnagel, L.

10.1101/280834 — developmental biology — Posted on 2018-03-13

1300 Protein-Protein Interaction Network Analysis and Identification of Key Players in N-hydroxy-nor-L-Arg (nor-NOHA) and N(omega)-hydroxy-L-arginine (NOHA) Mediated Pathways for Treatment of Cancer Through Arginase Inhibiton: Insights from Systems Biology

Ahammad, I.

10.1101/281030 — systems biology — Posted on 2018-03-13

1301 MoonFit, a minimal interface for fitting ODE dynamical models, bridging simulation by experimentalists and customization by C++ programmers

ROBERT, P. A.; Jönsson, H.; Meyer-Hermann, M.

10.1101/281188 — systems biology — Posted on 2018-03-13

1302 Effects of CEPA and 1-MCP on flower bud differentiation of apple cv. ‘Nagafu No.2’ grafted on different rootstocks

Li, W.; Chen, B.; Mao, J.; Li, X.; Su, J.; Dawuda, M. M.; Ma, Z.; Zuo, C.; An, Z.

10.1101/281303 — physiology — Posted on 2018-03-13

1303 Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN

Alves Faria Diniz, C. R.; Casarotto, P.; Fred, S. M.; Biojone, C.; Castren, E.; Joca, S. R. L.

10.1101/168708 — pharmacology and toxicology — Posted on 2018-03-13

1304 Encoding the expectation of a sensory stimulus

Zhang, L.; Chen, A. B.; Saha, D.; Li, C.; Raman, B.

10.1101/281071 — neuroscience — Posted on 2018-03-13

1305 The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

Kettunen, J.; Ritchie, S. C.; Anufrieva, O.; Lyytikäinen, L.-P.; Hernesniemi, J.; Karhunen, P. J.; Kuukasjärvi, P.; Laurikka, J.; Kähönen, M.; Lehtimäki, T.; Havulinna, A. S.; Salomaa, V.; Männistö, S.; Ala-Korpela, M.; Perola, M.; Inouye, M.; Würtz, P.

10.1101/280677 — epidemiology — Posted on 2018-03-13

1306 PaintOmics 3: a web resource for the pathway analysis and visualization of multi-omics data

Hernandez-de-Diego, R.; Tarazona, S.; Martinez-Mira, C.; Balzano-Nogueira, L.; Furio-Tari, P.; Pappas, G. J.; Conesa, A.

10.1101/281295 — bioinformatics — Posted on 2018-03-13

1307 Detection of race-specific resistance against Puccinia coronata f. sp. avenae in Brachypodium species

Omidvar, V.; Dugyala, S.; Li, F.; Rottschaefer, S.; Miller, M.; Ayliffe, M.; Moscou, M.; Kianian, S.; Figueroa, M.

10.1101/281568 — pathology — Posted on 2018-03-13

1308 Grammars of action in human behavior and evolution

Stout, D.; Chaminade, T.; Thomik, A.; Apel, J.; Faisal, A. A.

10.1101/281543 — neuroscience — Posted on 2018-03-13

1309 Physiological Significance of R-fMRI Indices in Detecting Structural Brain Lesions

Fan, Z.; Chen, X.; Qi, Z.-X.; Li, L.; Lu, B.; Jiang, C.-L.; Zhu, R.-Q.; Chen, L.; Yan, C.-G.

10.1101/281352 — neuroscience — Posted on 2018-03-13

1310 Parietal representations of stimulus features are amplified during memory retrieval and flexibly aligned with top-down goals

Favila, S. E.; Samide, R.; Sweigart, S. C.; Kuhl, B. A.

10.1101/280974 — neuroscience — Posted on 2018-03-13

1311 Internal gain modulations, but not changes in stimulus contrast, preserve the neural code

Lee, S.; Park, J.; Smirnakis, S.

10.1101/281444 — neuroscience — Posted on 2018-03-13

1312 Electrocortical Evidence for Long-Term Incidental Spatial Learning Through Modified Navigation Instructions

Wunderlich, A.; Gramann, K.

10.1101/280842 — neuroscience — Posted on 2018-03-13

1313 Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome

Strydom, A.; Heslegrave, A.; Startin, C. M.; Mok, K. Y.; Hardy, J.; Groet, J.; Nizetic, D.; The LonDownS consortium, ; Zetterberg, H.

10.1101/281139 — molecular biology — Posted on 2018-03-13

1314 Haemoproteus paraortalidum n. sp. in captive Black-fronted Piping-guans Aburria jacutinga (Galliformes, Cracidae): high prevalence in a population reintroduced into the wild

Ferreira-Junior, F. C.; Dutra, D. A.; Martins, N. R. d. S.; Valkiunas, G.; Braga, E. M.

10.1101/280990 — microbiology — Posted on 2018-03-13

1315 Reproducible integration of multiple sequencing datasets to form high-confidence SNP, indel, and reference calls for five human genome reference materials

Zook, J.; McDaniel, J.; Parikh, H.; Heaton, H.; Irvine, S. A.; Trigg, L.; Truty, R.; McLean, C. Y.; De La Vega, F. M.; Salit, M.; Genome in a Bottle Consortium,

10.1101/281006 — genomics — Posted on 2018-03-13

1316 Exact Tests of Zero Variance Component in Presence of Multiple VarianceComponents with Application to Longitudinal Microbiome Study

Zhai, J.; Knox, K. S.; Twigg, H. L.; Zhou, H.; Zhou, J. J.

10.1101/281246 — genomics — Posted on 2018-03-13

1317 Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency

Mulholland, C. B.; Traube, F. R.; Parsa, E.; Eckl, E.-M.; Schoenung, M.; Modic, M.; Bartoschek, M. D.; Stolz, P.; Ryan, J.; Carell, T.; Leonhardt, H.; Bultmann, S.

10.1101/281519 — cell biology — Posted on 2018-03-13

1318 Radioprotective role of cyanobacterial phycobilisomes

Klementiev, K. E.; Maksimov, E. G.; Gvozdev, D. A.; Tsoraev, G. V.; Protopopov, F. F.; Elanskaya, I. V.; Abramov, S. M.; Dyakov, M. Y.; Ilyin, V. K.; Nikolaeva, N. A.; Slonimskiy, Y. B.; Sluchanko, N. N.; Lebedev, V. M.; Spassky, A. V.; Friedrich, T.; Maksimov, G. V.; Paschenko, V. Z.; Rubin, A. B.

10.1101/281386 — biophysics — Posted on 2018-03-13

1319 Limited uptake of essential amino acid is effective for cancer therapy in metabolic networks of integrated constraint-based models

Tamura, T.

10.1101/281253 — bioinformatics — Posted on 2018-03-13

1320 Rapid, raw-read reference and identification (R4IDs): A flexible platform for rapid generic species ID using long-read sequencing technology.

Parker, J.; Helmstetter, A. J.; Papadopulos, A. S. T.

10.1101/281048 — bioinformatics — Posted on 2018-03-13

1321 Time-dependent mnemonic vulnerability induced by new-learning

Shen, F.; Ku, Y.; Wu, J.; Cui, Y.; Li, J.; Wang, Z.; Wang, H.; Kwok, S. C.

10.1101/281261 — neuroscience — Posted on 2018-03-13

1322 effect of buspirone on the H-reflex in acute spinal decerebrated mice

develle, y.; leblond, h.

10.1101/281451 — neuroscience — Posted on 2018-03-13

1323 Epithelial control of colonisation by Streptococcus pneumoniae at the human mucosal surface

Weight, C. M.; Venturini, C.; Pojar, S.; Jochems, S.; Reine, J.; Nikolaou, E.; Solorzano, C.; Anderson, C.; Noursadeghi, M.; Brown, J. S.; Ferreira, D. M.; Heyderman, R. S.

10.1101/281576 — immunology — Posted on 2018-03-13

1324 Accounting for location uncertainty in azimuthal telemetry data improves ecological inference

Gerber, B.; Hooten, M.; Peck, C.; Rice, M.; Gammonley, J.; Apa, A.; Davis, A.

10.1101/281584 — ecology — Posted on 2018-03-13

1325 Landscape-level DNA metabarcoding study in the Pannonian forests reveals differential effects of slope aspect on taxonomic and functional groups of fungi

Geml, J.

10.1101/281337 — ecology — Posted on 2018-03-13

1326 A Comparison of Temporal Response Function Estimation Methods for Auditory Attention Decoding

Wong, D. D. E.; Fuglsang, S. A.; Hjortkjaer, J.; Ceolini, E.; Slaney, M.; de Cheveigne, A.

10.1101/281345 — neuroscience — Posted on 2018-03-13

1327 Mid-Infrared Spectroscopy Study of Effects of Neonicotinoids on Forager Honey Bee (Apis mellifera) Fat Bodies and Their Connection to Colony Collapse Disorder

Feng, Y.; Luthra, A.; Ding, K.; Yang, Y.; Savage, J.; Wei, X.; Moeschter, R.; Ahuja, S.; Villegas, V.; Torbina, B.; Ahooja, A.; Ellis, T.; Boechler, A.-M.; Roberts, A.

10.1101/205112 — pharmacology and toxicology — Posted on 2018-03-13

1328 High-risk human papillomavirus in oral cavity squamous cell carcinoma

Palve, V.; Bagwan, J.; Krishnan, N. M.; Pareek, M.; Chandola, U.; Suresh, A.; Siddappa, G.; James, B. L.; Kekatpure, V.; Kuriakose, M. A.; Panda, B.

10.1101/082651 — cancer biology — Posted on 2018-03-13

1329 Epigenome-wide association in adipose tissue from the METSIM cohort

Orozco, L. D.; Farrell, C.; Hale, C.; Rubbi, L.; Rinaldi, A.; Civelek, M.; Pam, C.; Lam, L.; Montoya, D.; Edillor, C.; Seldin, M.; Boehnke, M.; Mohlke, K.; Jacobsen, S.; Kuusisto, J.; Laakso, M.; Lusis, A. J.; Pellegrini, M.

10.1101/223495 — genetics — Posted on 2018-03-13

1330 Evolutionary dynamics of bacteria in the gut microbiome within and across hosts

Garud, N. R.; Good, B. H.; Hallatschek, O.; Pollard, K. S.

10.1101/210955 — evolutionary biology — Posted on 2018-03-13

1331 VULCAN: Network Analysis of ER-α activation reveals reprogramming of GRHL2

Holding, A. N.; Giorgi, F. M.; Donnelly, A.; Cullen, A. E.; Selth, L. A.; Markowetz, F.

10.1101/266908 — cancer biology — Posted on 2018-03-13

1332 Evaluation of Caulobacter crescentus strain fitness at the genomic scale during growth in natural freshwater

Hentchel, K. L.; Reyes Ruiz, L. M.; Fiebig, A.; Curtis, P. D.; Coleman, M. L.; Crosson, S.

10.1101/279711 — microbiology — Posted on 2018-03-13

1333 A genome-wide innateness gradient defines the functional state of human innate T cells

Gutierrez-Arcelus, M.; Teslovich, N.; Mola, A. R.; Kim, H.; Hannes, S.; Slowikowski, K.; Watts, G. F. M.; Brenner, M.; Raychaudhuri, S.; Brennan, P. J.

10.1101/280370 — immunology — Posted on 2018-03-13

1334 4D imaging reveals stage dependent random and directed cell motion during somite morphogenesis

McColl, J.; Mok, G. F.; Lippert, A. H.; Ponjavic, A.; Munsterberg, A.

10.1101/280883 — developmental biology — Posted on 2018-03-13

1335 Inferring synaptic inputs from spikes with a conductance-based neural encoding model

Latimer, K.; Rieke, F.; Pillow, J. W.

10.1101/281089 — neuroscience — Posted on 2018-03-13

1336 Flexible top-down modulation in human ventral temporal cortex

Zhang, R.; Kay, K.

10.1101/279935 — neuroscience — Posted on 2018-03-13

1337 Psychophysical reverse correlation reflects both sensory and decision-making processes

Okazawa, G.; Sha, L.; Purcell, B. A.; Kiani, R.

10.1101/273680 — neuroscience — Posted on 2018-03-13

1338 A Comparison of Temporal Response Function Estimation Methods for Auditory Attention Decoding

Wong, D. D. E.; Asp Fuglsang, S. A.; Hjortkjaer, J.; Ceolini, E.; Slaney, M.; de Cheveigne, A.

10.1101/281345 — neuroscience — Posted on 2018-03-13

1339 Coordinated cerebellar climbing fiber activity is gated by behavioral context in a voluntary motor regime

Heffley, W.; Song, E. Y.; Xu, Z.; Taylor, B.; Hughes, M. A.; McKinney, A.; Joshua, M.; Hull, C.

10.1101/281055 — neuroscience — Posted on 2018-03-13

1340 Early-life social environment alters juvenile behavior and neuroendocrine function in a highly social cichlid fish

Solomon-Lane, T. K.; Hofmann, H. A.

10.1101/281097 — neuroscience — Posted on 2018-03-13

1341 Wheat shovelomics II: Revealing relationships between root crown traits and crop growth

Slack, S.; York, L. M.; Roghazai, Y.; Lynch, J.; Bennett, M.; Foulkes, J.

10.1101/280917 — plant biology — Posted on 2018-03-13

1342 A combinatorial lipid code shapes the electrostatic landscape of plant endomembranes

Platre, M. P.; Doumane, M.; Bayle, V.; Simon, M. L. A.; Maneta-Peyret, L.; Fouillen, L.; Stanislas, T.; Armengot, L.; Pejchar, P.; Caillaud, M.-C.; Potocky, M.; Copic, A.; Moreau, P.; Jaillais, Y.

10.1101/278135 — plant biology — Posted on 2018-03-13

1343 Utp14 interaction with the Small Subunit Processome

Black, J. J.; Wang, Z.; Goering, L. M.; Johnson, A.

10.1101/280859 — molecular biology — Posted on 2018-03-13

1344 Serum glycoprotein biomarker validation for esophageal adenocarcinoma and application to Barrett’s surveillance

Shah, A. K.; Hartel, G.; Brown, I.; Winterford, C.; Na, R.; Le Cao, K.-A.; Spicer, B. A.; Dunstone, M.; Phillips, W. A.; Lord, R. V.; Barbour, A. P.; Watson, D. I.; Joshi, V.; Whiteman, D. C.; Hill, M. M.

10.1101/281220 — biochemistry — Posted on 2018-03-13

1345 Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

10.1101/281121 — cell biology — Posted on 2018-03-13

1346 Pseudomonas aeruginosa partitioning protein ParB acts as a nucleoid-associated protein binding to multiple copies of a parS-related motif.

Kawalek, A.; Bartosik, A. A.; Glabski, K.; Jagura-Burdzy, G.

10.1101/280743 — molecular biology — Posted on 2018-03-13

1347 Patterns of genetic differentiation and the footprints of historical migrations in the Iberian Peninsula

Bycroft, C.; Fernandez-Rozadilla, C.; Ruiz-Ponte, C.; Quintela-Garcia, I.; Carracedo, A.; Donnelly, P.; Myers, S.

10.1101/250191 — genomics — Posted on 2018-03-12

1348 The contribution of mitochondrial metagenomics to largescale data mining and phylogenetic analysis of Coleoptera

Linard, B.; Crampton-Platt, A.; Moriniere, J.; Timmermans, M. J.; Andujar, C.; Arribas, P.; Miller, K. E.; Lipecki, J.; Favreau, E.; Hunter, A.; Gomez-Rodriguez, C.; Barton, C.; Nie, R.; Gillett, C. P.; Breeschoten, T.; Bocak, L.; Vogler, A. P.

10.1101/280792 — evolutionary biology — Posted on 2018-03-12

1349 Detection and classification of hard and soft sweeps from unphased genotypes by multilocus genotype identity

Harris, A. M.; Garud, N. R.; DeGiorgio, M.

10.1101/281063 — evolutionary biology — Posted on 2018-03-12

1350 A genome-wide assessment of the ancestral neural crest gene regulatory network

Hockman, D.; Chong-Morrison, V.; Gavriouchkina, D.; Green, S.; Amemiya, C.; Smith, J. J.; Bronner, M.; Sauka-Spengler, T.

10.1101/275875 — developmental biology — Posted on 2018-03-12

1351 Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types

PCAWG Transcriptome Core Group, ; Calabrese, C.; Davidson, N. R.; Fonseca, N. A.; He, Y.; Kahles, A.; Lehmann, K.-V.; Liu, F.; Shiraishi, Y.; Soulette, C. M.; Urban, L.; Demircioglu, D.; Greger, L.; Li, S.; Liu, D.; Perry, M. D.; Xiang, L.; Zhang, F.; Zhang, J.; Bailey, P.; Erkek, S.; Hoadley, K. A.; Hou, Y.; Kilpinen, H.; Korbel, J. O.; Marin, M. G.; Markowski, J.; Nandi, T.; Pan-Hammarström, Q.; Pedamallu, C. S.; Siebert, R.; Stark, S. G.; Su, H.; Tan, P.; Waszak, S. M.; Yung, C.; Zhu, S.; PCAWG Transcriptome Working Group, ; Awadalla, P.; Creighton, C. J.; Meyerson, M.; Ouellette,

10.1101/183889 — genomics — Posted on 2018-03-12

1352 Automation of citation screening in pre-clinical systematic reviews

Liao, J.; Ananiadou, S.; Currie, G. L.; Howard, B. E.; Rice, A.; Sena, E. S.; Thomas, J.; Varghese, A.; Macleod, M. R.

10.1101/280131 — scientific communication and education — Posted on 2018-03-12

1353 Single-strand DNA processing: phylogenomics and sequence diversity of a superfamily of potential prokaryotic HuH endonucleases

Quentin, Y.; Siguier, P.; Chandler, M.; Fichant, G.

10.1101/279083 — genomics — Posted on 2018-03-12

1354 Mitigation of coral bleaching by antioxidants

Yudowski, G.; Roberson, L.; Marty-Rivera, M.

10.1101/281014 — ecology — Posted on 2018-03-12

1355 BART: a transcription factor prediction tool with query gene sets or epigenomic profiles

Wang, Z.; Civelek, M.; Miller, C.; Sheffield, N.; Guertin, M. J.; Zang, C.

10.1101/280982 — bioinformatics — Posted on 2018-03-12

1356 Wheat shovelomics I: A field phenotyping approach for characterising the structure and function of root systems in tillering species

York, L. M.; Slack, S.; Bennett, M. J.; Foulkes, M. J.

10.1101/280875 — plant biology — Posted on 2018-03-12

1357 Coupling between cerebral blood flow and cerebral blood volume: Contributions of different vascular compartments

Wesolowski, R.; Blockley, N. P.; Driver, I. D.; Francis, S. T.; Gowland, P. A.

10.1101/202838 — neuroscience — Posted on 2018-03-12

1358 Causal evidence for mnemonic metacognition in human precuneus

Ye, Q.; Zou, F.; Lau, H.; Hu, Y.; Kwok, S. C.

10.1101/280750 — neuroscience — Posted on 2018-03-12

1359 Evaluation of Whole Exome Sequencing as an Alternative of BeadChip and Whole Genome Sequencing in Human Population Genetic Analysis

Maroti, Z.; Boldogkoi, Z.; Tombacz, D.; Snyder, M.; Kalmar, T.

10.1101/280552 — genomics — Posted on 2018-03-12

1360 Capturing diverse microbial sequence with comprehensive and scalable probe design

Siddle, K. J.; Metsky, H. C.; Gladden-Young, A.; Qu, J.; Yang, D. K.; Brehio, P.; Goldfarb, A.; Piantadosi, A.; Wohl, S.; Lin, A. E.; Barnes, K. G.; Tully, D. C.; Hennigan, S.; Barbosa-Lima, G.; Vieira, Y. R.; Paul, L. M.; Tan, A. L.; Garcia, K. F.; Parham, L. A.; Odia, I.; Eromon, P.; Folarin, O. A.; Goba, A.; Viral Hemorrhagic Fever Consortium, ; Simon-Loriere, E.; Hensley, L.; Balmaseda, A.; Harris, E.; Allen, T. M.; Runstadler, J. A.; Smole, S.; Bozza, F. A.; Souza, T. M.; Isern, S.; Michael, S. F.; Lorenzana, I.; Gehrke, L.; Bosch, I.; Ebel, G.; Happi, C.; Grant, D.; Park, D. J.; Gnirke,

10.1101/279570 — genomics — Posted on 2018-03-12

1361 The tumor suppressor BRCA1/BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans

Li, Q.; Saito, T. T.; Deshong, A. J.; Martinez Garcia, M.; Nadarajan, S.; Lawrence, K. S.; Checchi, P. M.; Colaiacovo, M. P.; Engebrecht, J.

10.1101/280909 — genetics — Posted on 2018-03-12

1362 A microcalorimetric approach for investigating stoichiometric constraints on the standard metabolic rate of a small invertebrate

Ruiz, T.; Bec, A.; Danger, M.; Koussoroplis, A.-M.; Aguer, J.-P.; Morel, J.-P.; Morel-Desrosiers, N.

10.1101/279562 — ecology — Posted on 2018-03-12

1363 FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results

DeVito, N. J.; Bacon, S.; Goldacre, B.

10.1101/266452 — clinical trials — Posted on 2018-03-12

1364 A generalizable experimental framework for automated cell growth and laboratory evolution

Wong, B. G.; Mancuso, C. P.; Kiriakov, S.; Bashor, C. J.; Khalil, A. S.

10.1101/280867 — systems biology — Posted on 2018-03-12

1365 GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys

Romaus-Sanjurjo, D.; Ledo-Garcia, R.; Fernandez-Lopez, B.; Hanslik, K.; Morgan, J. R.; Barreiro-Iglesias, A.; Rodicio, M. C.

10.1101/280891 — neuroscience — Posted on 2018-03-12

1366 Mosaic patterns of B-vitamin synthesis and utilization in a natural marine microbial community

Gomez-Consarnau, L.; Sachdeva, R.; Gifford, S. M.; Cutter, L. S.; Fuhrman, J.; Sanudo-Wilhelmy, S. A.; Moran, M. A.

10.1101/280438 — microbiology — Posted on 2018-03-12

1367 Differential regulation of activation and differentiation processes in CD4+ T cell populations and their single-cell level heterogeneity

Bradley, A.; Hashimoto, T.; Ono, M.

10.1101/280818 — immunology — Posted on 2018-03-12

1368 Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution

Gilabert, A.; Otto, T.; Rutledge, G.; Franzon, B.; Ollomo, B.; Arnathau, C.; Durand, P.; Moukodoum, N.; Okouga, A.-P.; Ngoubangoye, B.; Makanga, B.; Boudenga, L.; Paupy, C.; Renaud, F.; Prugnolle, F.; Rougeron, V.

10.1101/205302 — evolutionary biology — Posted on 2018-03-12

1369 clusterExperiment and RSEC: A Bioconductor package and framework for clustering of single-cell and other large gene expression datasets

Risso, D.; Purvis, L.; Fletcher, R.; Das, D.; Ngai, J.; Dudoit, S.; Purdom, E.

10.1101/280545 — bioinformatics — Posted on 2018-03-12

1370 Synaptic plasticity onto inhibitory neurons as a mechanism for ocular dominance plasticity.

Bono, J.; Clopath, C.

10.1101/280511 — neuroscience — Posted on 2018-03-12

1371 Neuronal signature of social novelty exploration in the VTA: implication for Autism Spectrum Disorder

Bariselli, S.; Hornberg, H.; Prevost-Solie, C.; Musardo, S.; Hatstatt-Burkle, L.; Scheiffele, P.; Bellone, C.

10.1101/280537 — neuroscience — Posted on 2018-03-12

1372 From proteins to polysaccharides: lifestyle and genetic evolution of Coprothermobacter proteolyticus.

Kunath, B.; Delogu, F.; Arntzen, M.; Eijsink, V. G. H.; Hvidsten, T. R.; Pope, P. B.

10.1101/280602 — microbiology — Posted on 2018-03-12

1373 GetOrganelle: a simple and fast pipeline for de novo assembly of a complete circular chloroplast genome using genome skimming data

Jin, J.-J.; Yu, W.-B.; Yang, J.-B.; Song, Y.; Yi, T.-S.; Li, D.-Z.

10.1101/256479 — bioinformatics — Posted on 2018-03-12

1374 OMCD: OncoMir Cancer Database

Sarver, A.; Sarver, A.; Yuan, C.; Subramanian, S.

10.1101/279125 — bioinformatics — Posted on 2018-03-12

1375 Improved Prokaryotic Gene Prediction Yields Insights into Transcription and Translation Mechanisms on Whole Genome Scale

Lomsadze, A.; Gemayel, K.; Tang, S.; Borodovsky, M.

10.1101/193490 — genomics — Posted on 2018-03-12

1376 Clusterdv, a simple density-based clustering method that is robust, general and automatic.

Marques, J. C.; Orger, M. B.

10.1101/224840 — bioinformatics — Posted on 2018-03-12

1377 Signalling maps in cancer research: construction and data analysis

Kondratova, M.; Sompairac, N.; Barillot, E.; Zinovyev, A.; Kuperstein, I.

10.1101/089409 — systems biology — Posted on 2018-03-12

1378 Large Meta-Analysis in the CHARGE Consortium Provides Evidence For an Association of Serum Vitamin D With Pulmonary Function

Xu, J.; Bartz, T. M.; Chittoor, G.; Eiriksdottir, G.; Manichaikul, A. W.; Sun, F.; Terzikhan, N.; Zhou, X.; Booth, S. L.; Brusselle, G. G.; de Boer, I. H.; Fornage, M.; Frazier-Wood, A. C.; Graff, M.; Gudnason, V.; Harris, T. B.; Hofman, A.; Hou, R.; Houston, D. K.; Jacobs, D. R.; Kritchevsky, S. B.; Latourelle, J.; Lemaitre, R. N.; Lutsey, P. L.; O'Connor, G.; Oelsner, E. C.; Pankow, J. S.; Psaty, B. M.; Rohde, R. R.; Rich, S. S.; Rotter, J. I.; Smith, L. J.; Stricker, B. H.; Voruganti, V. S.; Wang, T. J.; Zillikens, M. C.; Barr, R. G.; Dupuis, J.; Gharib, S. A.; Lahousse, L.; London, S. J.;

10.1101/144717 — epidemiology — Posted on 2018-03-12

1379 Aneuploidy Promotes Intestinal Dysplasia in Drosophila

Resende, L. P.; Monteiro, A.; Bras, R.; Lopes, T.; Sunkel, C. E.

10.1101/280768 — developmental biology — Posted on 2018-03-12

1380 Genes relocated between Drosophila chromosome arms evolve under relaxed selective constraints relative to non-relocated genes

Hart, M. L. I.; Vu, B. L.; Bolden, Q.; Chen, K. T.; Oakes, C. L.; Zoronjic, L.; Meisel, R.

10.1101/178582 — genetics — Posted on 2018-03-12

1381 PANOPLY: Omics-guided drug prioritization method tailored to an individual patient

Kalari, K. R.; Sinnwell, J. P.; Thompson, K. J.; Tang, X.; Carlson, E. E.; Yu, J.; Vedell, P. T.; Ingle, J. N.; Weinshilboum, R.; Wang, L.; Boughey, J. C.; Goetz, M. P.; Suman, V. J.

10.1101/176396 — bioinformatics — Posted on 2018-03-12

1382 A cortical active-suppression mechanism facilitates the distraction-invariant selective processing of concurrent speech

Fiedler, L.; Woestmann, M.; Herbst, S. K.; Obleser, J.

10.1101/238642 — neuroscience — Posted on 2018-03-12

1383 Structural priming is supported by different components of non-declarative memory: Evidence from priming across the lifespan

Heyselaar, E.; Wheeldon, L.; Segaert, K.

10.1101/190355 — neuroscience — Posted on 2018-03-12

1384 New perspectives on multilocus ancestry informativeness

Tal, O.; Tran, T. D.

10.1101/273466 — genetics — Posted on 2018-03-12

1385 Hamiltonian distributed chaos in DNA

Bershadskii, A.

10.1101/272054 — biophysics — Posted on 2018-03-12

1386 Dynamic Kinetochore Size Regulation Promotes Microtubule Capture And Chromosome Biorientation In Mitosis

Sacristan, C.; Ahmad, M.; Keller, J.; Fermie, J.; Groenewold, V.; Tromer, E.; Fish, A.; Melero, R.; Carazo, J. M.; Klumperman, J.; Musacchio, A.; Perrakis, A.; Kops, G. J.

10.1101/279398 — cell biology — Posted on 2018-03-12

1387 Automated Gleason grading of prostate cancer tissue microarrays via deep learning

Arvaniti, E.; Fricker, K. S.; Moret, M.; Rupp, N. J.; Hermanns, T.; Fankhauser, C.; Wey, N.; Wild, P. J.; Rueschoff, J. H.; Claassen, M.

10.1101/280024 — bioinformatics — Posted on 2018-03-12

1388 Auditory motion does not modulate spiking activity in visual motion processing areas MT and MST

Chaplin, T. A.; Allitt, B. J.; Hagan, M. A.; Rosa, M. G.; Rajan, R.; Lui, L. L.

10.1101/204529 — neuroscience — Posted on 2018-03-12

1389 Broad-scale mercury bioaccumulation patterns in two freshwater sport fishes: testing the role of growth dilution in a warming climate

Thomas, S. M.; Melles, S. J.; Bhavsar, S. P.

10.1101/280107 — ecology — Posted on 2018-03-12

1390 A morphological and molecular analysis of the species diversity of the cichlid genus Petrochromis from Lake Tanganyika (Teleostei: Cichlidae)

Mattsson, C.

10.1101/280263 — zoology — Posted on 2018-03-12

1391 Strain-level diversity drives alternative community types in millimeter scale granular biofilms

Leventhal, G. E.; Boix, C.; Kuechler, U.; Enke, T. N.; Sliwerska, E.; Holliger, C.; Cordero, O. X.

10.1101/280271 — microbiology — Posted on 2018-03-12

1392 The genomic architecture of a rapid island radiation: recombination rate variation, chromosome structure, and genome assembly of the hawaiian cricket Laupala

Blankers, T.; Oh, K. P.; Bombarely, A.; Shaw, K. L.

10.1101/160952 — evolutionary biology — Posted on 2018-03-12

1393 The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

Kettunen, J.; Ritchie, S.; Anufrieva, O.; Lyytikainen, L.-P.; Hernesniemi, J.; Karhunen, P. J.; Kuukasjarvi, P.; Laurikka, J.; Kahonen, M.; Lehtimaki, T.; Havulinna, A. S.; Salomaa, V.; Mannisto, S.; Ala-Korpela, M.; Perola, M.; Inouye, M.; Wyrtz, P.

10.1101/280677 — epidemiology — Posted on 2018-03-12

1394 Theta-modulation drives the emergence of network-wide connectivity patterns underlying replay in a a model of hippocampal place cells

Theodoni, P.; Rovira, B.; Wang, Y.; Roxin, A.

10.1101/118489 — neuroscience — Posted on 2018-03-12

1395 Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations

Lam, M. M. C.; Wick, R. R.; Wyres, K. L.; Gorrie, C.; Judd, L. M.; Jenney, A.; Brisse, S.; Holt, K. E.

10.1101/098178 — microbiology — Posted on 2018-03-12

1396 High affinity Na+ transport by wheat HKT1;5 is blocked by K+

Xu, B.; Hrmova, M.; Gilliham, M.

10.1101/280453 — plant biology — Posted on 2018-03-12

1397 Dynamic integration of conceptual information during learning

Inhoff, M. C.; Libby, L. A.; Noguchi, T.; Love, B. C.; Ranganath, C.

10.1101/280362 — neuroscience — Posted on 2018-03-12

1398 Breast cancer susceptibility: an integrative analysis of genomic data

Mocellin, S.; Valpione, S.; Rossi, C. R.; Pooley, K.

10.1101/279984 — cancer biology — Posted on 2018-03-12

1399 Principles of Computer Numerical Controlled Machining Applied to Cranial Microsurgery

Ghanbari, L.; Rynes, M.; Hu, J.; Sousa Shulman, D.; Johnson, G.; Laroque, M.; Shull, G.; Kodandaramaiah, S. B.

10.1101/280461 — bioengineering — Posted on 2018-03-12

1400 Automated Adherent Cell Elimination by a High-Speed Laser Mediated by a Light-Responsive Polymer

Hayashi, Y.; Matsumoto, J.; Kumagai, S.; Morishita, K.; Xiang, L.; Kobori, Y.; Hori, S.; Suzuki, M.; Kanamori, T.; Hotta, K.; Sumaru, K.

10.1101/280487 — bioengineering — Posted on 2018-03-12

1401 Neural representations of aversive value encoding in pain catastrophizers

Brown, C.; Almarzouki, A. F.; Brown, R. J.; Jones, A. K.

10.1101/279992 — neuroscience — Posted on 2018-03-12

1402 Mercury-methylating bacteria are associated with zooplankton: a proof-of-principle survey in the Baltic Sea

Gorokhova, E.; Soerensen, A. L.; Motwani, N. H.

10.1101/279976 — microbiology — Posted on 2018-03-12

1403 Prolonged lag time results in small colony variants and reflects a sub-population of persisters in vivo

Vulin, C.; Leimer, N.; Huemer, M.; Ackermann, M.; Zinkernagel, A. S.

10.1101/279968 — microbiology — Posted on 2018-03-12

1404 A genome-wide innateness gradient defines the functional state of human innate T cells

Gutierrez-Arcelus, M.; Teslovich, N.; Mola, A. R.; Kim, H.; Hannes, S.; Slowikowski, K.; Watts, G. F. M.; Brenner, M.; Raychaudhuri, S.; Brennan, P. J.

10.1101/280370 — immunology — Posted on 2018-03-12

1405 Embryonic gene transcription in the spiny mouse (Acomys cahirinus): a new model of embryonic genome activation.

Mamrot, J.; Gardner, D. K.; Temple-Smith, P.; Dickinson, H.

10.1101/280412 — genomics — Posted on 2018-03-12

1406 Passenger mutations in 2500 cancer genomes: Overall molecular functional impact and consequences

Kumar, S.; Warrell, J.; Li, S.; McGillivray, P.; Meyerson, W.; Salichos, L.; Harmanci, A.; Martinez-Fundichely, A.; Chan, C. W. Y.; Nielsen, M.; Lochovsky, L.; Zhang, Y.; Li, X.; Pedersen, J. S.; Herrmann, C.; Getz, G.; Khurana, E.; Gerstein, M.; PCAWG Drivers and Functional Interpretation Group, ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network,

10.1101/280446 — genomics — Posted on 2018-03-12

1407 Using synthetic semiochemicals to train canines to detect bark beetle-infested trees

Johansson, A.; Birgersson, G.; Schlyter, F.

10.1101/262386 — ecology — Posted on 2018-03-12

1408 Comparative Transcriptomic and Metabolomic Analyses in Response to Cold in Tartary Buckwheat (Fagopyrum tataricum)

Jeon, J.; Kim, J. K.; Wu, Q.; Park, S. U.

10.1101/278432 — systems biology — Posted on 2018-03-12

1409 A homing CRISPR mouse resource for barcoding and lineage tracing

Kalhor, R.; Kalhor, K.; Leeper, K.; Graveline, A.; Mali, P.; Church, G. M.

10.1101/280289 — synthetic biology — Posted on 2018-03-12

1410 CRISPR-Tag: an Efficient DNA Tagging System in Living Cells

Chen, B.; Zou, W.; Huang, B.

10.1101/280495 — cell biology — Posted on 2018-03-12

1411 Dysregulation of the engulfment pathway in the gut fuels Inflammatory Bowel Disease

Suarez, K.; Lim, E.; Singh, S.; Pereira, M.; Joosen, L. P.; Ibeawuchi, S.-R.; Dunkel, Y.; Mittal, Y.; Ho, S. B.; Chattopadhyay, R.; Guma, M.; Boland, B. S.; Dulai, P. S.; Sandborn, W. J.; Ghosh, P.; Das, S.

10.1101/280172 — cell biology — Posted on 2018-03-12

1412 Predictive entrainment of natural speech through two fronto-motor top-down channels

Park, H.; Thut, G.; Gross, J.

10.1101/280032 — neuroscience — Posted on 2018-03-11

1413 Synaptic transmission modulates while non-synaptic processes govern the transition from pre-ictal to seizure activity in vitro

Bikson, M.; Ruiz-Nuno, A.; Miranda, D.; Kronberg, G.; Jiruska, P.; Fox, J. E.; Jefferys, J. G. R.

10.1101/280321 — neuroscience — Posted on 2018-03-11

1414 Mutations in Pan species are shaped by demographic history and harbor lineage-specific functions

Han, S.; Andres, A. M.; Marques-Bonet, T.; Kuhlwilm, M.

10.1101/280016 — genomics — Posted on 2018-03-11

1415 A morphological and molecular analysis of the species diversity of the cichlid genus Petrochromis from Lake Tanganyika (Teleostei: Cichlidae)

Mattsson, C.

10.1101/280263 — zoology — Posted on 2018-03-11

1416 Expected reward value and reward uncertainty have temporally dissociable effects on memoryformation

Stanek, J. K.; Dickerson, K. C.; Chiew, K. S.; Clement, N. J.; Adcock, R. A.

10.1101/280164 — neuroscience — Posted on 2018-03-11

1417 Strain-level diversity drives alternative community types in millimeter scale granular biofilms

Leventhal, G.; Boix, C.; Kuechler, U.; Enke, T. N.; Sliwerska, E.; Holliger, C.; Cordero, O. X.

10.1101/280271 — microbiology — Posted on 2018-03-11

1418 Assembly of a Parts List of the Human Mitotic Cell Cycle Machinery

Giotti, B.; Chen, S.-H.; Barnett, M. W.; Regan, T.; Ly, T.; Wiemann, S.; Hume, D. A.; Freeman, T. C.

10.1101/280339 — genomics — Posted on 2018-03-11

1419 The BRCA1-BARD1 complex associates with the synaptonemal complex and pro-crossover factors and influences RAD-51 dynamics during Caenorhabditis elegans meiosis

Janisiw, E.; Dello Stritto, M. R.; Jantsch, V.; Silva, N.

10.1101/280214 — genetics — Posted on 2018-03-11

1420 Molecular Dynamics Simulations of the FtsZ mutant G105S

Muthukumar, V.

10.1101/280248 — biochemistry — Posted on 2018-03-11

1421 Molecular Dynamics Simulation of the E. coli FtsZ

Muthukumar, V.

10.1101/280222 — biochemistry — Posted on 2018-03-11

1422 Disabling Gβγ SNARE interaction in transgenic mice disrupts GPCR-mediated presynaptic inhibition leading to physiological and behavioral phenotypes.

Zurawski, Z.; Thompson Gray, A. D.; Brady, L. J.; Page, B.; Church, E.; Harris, N. A.; Dohn, M. R.; Yim, Y. Y.; Hyde, K.; Mortlock, D. P.; Winder, D. G.; Alford, S.; Jones, C. K.; Hamm, H. E.

10.1101/280347 — neuroscience — Posted on 2018-03-11

1423 Prevalence of Antibiotic Resistance in Commensal Escherichia Coli among the Children in Rural Hill Communities of North East India

Singh, A. K.; Das, S.; Singh, S.; Gajamer, V. R.; Pradhan, N.; Lepcha, Y. D.; Tiwari, H. K.

10.1101/280198 — microbiology — Posted on 2018-03-11

1424 Polyamines support myogenesis by facilitating myoblast migration

Brenner, S.; Feiler, Y.; Kahana, C.

10.1101/280206 — cell biology — Posted on 2018-03-11

1425 Molecular Dynamics simulation of the E. coli FtsZ dimer

Muthukumar, V.

10.1101/280230 — biochemistry — Posted on 2018-03-11

1426 Distinguishing the roles of dorsolateral and anterior PFC in visual metacognition

Shekhar, M.; Rahnev, D.

10.1101/280081 — animal behavior and cognition — Posted on 2018-03-11

1427 GeneQC: A quality control tool for gene expression estimation based on RNA-sequencing reads mapping

McDermaid, A.; Chen, X.; Zhang, Y.; Xie, J.; Wang, C.; Ma, Q.

10.1101/266445 — bioinformatics — Posted on 2018-03-11

1428 Histone modifications and active gene expression are associated with enhanced CRISPR activity in de-silenced chromatin

Daer, R.; Barrett, C. M.; Haynes, K. A.

10.1101/228601 — synthetic biology — Posted on 2018-03-11

1429 Analog closed-loop modulation of hippocampal pyramidal cells dissociates gamma frequency and amplitude

Nicholson, E.; Kuzmin, D.; Leite, M.; Akam, T. E.; Kullmann, D. M.

10.1101/279588 — neuroscience — Posted on 2018-03-11

1430 SArKS: Discovering Gene Expression Regulatory Motifs And Domains By Suffix Array Kernel Smoothing

Wylie, D. C.; Hofmann, H. A.; Zemelman, B. V.

10.1101/133934 — bioinformatics — Posted on 2018-03-11

1431 An agent-based model of dengue virus transmission shows how multiple uncertainties about vaccine efficacy influence public health impact projections

Perkins, A.; Reiner, R.; Espana, G.; ten Bosch, Q.; Verma, A.; Liebman, K.; Paz Soldan, V.; Elder, J.; Morrison, A. C.; Stoddard, S.; Kitron, U.; Vazquez-Prokopec, G. M.; Scott, T. W.; Smith, D. L.

10.1101/082396 — epidemiology — Posted on 2018-03-11

1432 3D micro-environment regulates NF-κβ dependent adhesion to induce monocyte differentiation

Kumar Sinha, D.; Bhattacharya, A.; Agarwal, M.; Mukherjee, R.; Sen, P.

10.1101/279943 — cell biology — Posted on 2018-03-11

1433 Mitochondrial Fusion Suppresses Pancreatic Cancer Growth via Reduced Oxidative Metabolism

Yu, M.; Huang, Y.; Deorukhkar, A.; Fujimoto, T.; Govindaraju, S.; Molkentine, J.; Lin, D.; Kang, Y.; Koay, E.; Fleming, J.; Gupta, S.; Maitra, A.; Taniguchi, C.

10.1101/279745 — cancer biology — Posted on 2018-03-11

1434 Broad-scale mercury bioaccumulation patterns in two freshwater sport fishes: testing the role of growth dilution in a warming climate

Thomas, S. M.; Melles, S. J.; Bhavsar, S. P.

10.1101/280107 — ecology — Posted on 2018-03-11

1435 Automated Gleason grading of prostate cancer tissue microarrays via deep learning

Arvaniti, E.; Fricker, K. S.; Moret, M.; Rupp, N. J.; Hermanns, T.; Fankhauser, C.; Wey, N.; Wild, P. J.; Rueschoff, J. H.; Claassen, M.

10.1101/280024 — bioinformatics — Posted on 2018-03-11

1436 Testing the behavioral origins of novelty: did increased aggression lead to scale-eating in pupfishes?

St. John, M. E.; McGirr, J. A.; Martin, C. H.

10.1101/280123 — evolutionary biology — Posted on 2018-03-11

1437 Spatial extinction date estimation: a novel method for reconstructing spatiotemporal patterns of extinction and identifying potential zones of rediscovery

Carlson, C. J.; Burgio, K. R.; Dallas, T. A.; Bond, A. L.

10.1101/279679 — ecology — Posted on 2018-03-11

1438 Expectations May Influence the Effects of Transcranial Direct Current Stimulation

Rabipour, S.; Wu, A. D.; Davidson, P. S. R.; Iacoboni, M.

10.1101/279554 — neuroscience — Posted on 2018-03-10

1439 Bacteriophage cooperation suppresses CRISPR-Cas3 and Cas9 immunity

Borges, A. L.; Zhang, J. Y.; Rollins, M.; Osuna, B. A.; Wiedenheft, B.; Bondy-Denomy, J.

10.1101/279141 — microbiology — Posted on 2018-03-10

1440 Drosophila egg-derived tyrosine phosphatase (EDTP): a novel target for improved survivorship to prolonged anoxia and cellular protein aggregates

Xiao, C.; Qiu, S.; Li, X.; Luo, D.-J.; Robertson, R. M.; Liu, G.-P.

10.1101/279885 — genetics — Posted on 2018-03-10

1441 Microhabitat Heterogeneity Promotes Partition of Resources by Syntopic Peromyscus in a Midlatitude Temperate Forest

De la Cruz-Arguello, I. M.; Castro-Campillo, A.; Zavala-Hurtado, A.; Salame-Mendez, A.; Ramirez-Pulido, J.

10.1101/278390 — ecology — Posted on 2018-03-10

1442 A death pheromone, oleic acid, triggers hygienic behavior in honey bees (Apis mellifera L.)

McAfee, A.; Chapman, A.; Iovinella, I.; Gallagher-Kurtzke, Y.; Collins, T. F.; Higo, H.; Madilao, L. L.; Pelosi, P.; Foster, L. J.

10.1101/231902 — animal behavior and cognition — Posted on 2018-03-10

1443 A Lotus japonicus E3 ligase interacts with the Nod factor receptor 5 and positively regulates nodulation

Tsikou, D.; Ramirez, E. E.; Psarrakou, I. S.; Wong, J. E.; Jensen, D. B.; Isono, E.; Radutoiu, S.; Papadopoulou, K. K.

10.1101/269506 — plant biology — Posted on 2018-03-10

1444 Association between peripheral inflammation and DATSCAN data of the striatal nuclei in different motor subtypes of Parkinson Disease

Sanjari Moghaddam, H.; Ghazi Sherbaf, F.; Mojtahed Zadeh, M.; Ashraf-Ganjouei, A.; Aarabi, M. H.

10.1101/247080 — neuroscience — Posted on 2018-03-10

1445 MeShClust: an intelligent tool for clustering DNA sequences

James, B. T.; Luczak, B. B.; Girgis, H. Z.

10.1101/207720 — bioinformatics — Posted on 2018-03-10

1446 Mavacamten stabilizes a folded-back sequestered super-relaxed state of β-cardiac myosin

Anderson, R. L.; Trivedi, D. V.; Sarkar, S. S.; Henze, M.; Ma, W.; Gong, H.; Rogers, C. S.; Wong, F. L.; Morck, M.; Seidman, J. G.; Ruppel, K. M.; Irving, T. C.; Cooke, R.; Green, E. M.; Spudich, J. A.

10.1101/266783 — biochemistry — Posted on 2018-03-10

1447 Distress tolerance across self-report, behavioral and psychophysiological domains in women with eating disorders and healthy controls

Yiu, A.; Christensen, K.; Arlt, J. M.; Chen, E.

10.1101/170217 — physiology — Posted on 2018-03-10

1448 Many rare genetic variants have unrecognized large-effect disruptions to exon recognition

Cheung, R.; Insigne, K. D.; Yao, D.; Burghard, C. P.; Jones, E. M.; Goodman, D. B.; Kosuri, S.

10.1101/199927 — genetics — Posted on 2018-03-10

1449 Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.

Tylee, D. S.; Sun, J.; Hess, J. L.; Tahir, M. A.; Sharma, E.; Malik, R.; Worrall, B. B.; Levine, A. J.; Martinson, J. J.; Nejenstev, S.; Speed, D.; Fischer, A.; Mick, E.; Walker, B. R.; Crawford, A.; Grant, S. F. A.; Polychronakos, C.; Bradfield, J. P.; Sleiman, P. M. A.; Hakonarson, H.; Ellinghaus, E.; Elder, J. T.; Tsoi, L. C.; Trembath, R. C.; Barker, J. N.; Franke, A.; Dehghan, A.; The 23andMe Research Team, ; The Inflammation Working Group of the CHARGE Consortium, ; The METASTROKE Consortium of the International Stroke Genetics Consortium, ; The Netherlands Twin Registry, ; The neuro

10.1101/070730 — bioinformatics — Posted on 2018-03-10

1450 Compendium of Synovial Signatures Identifies Pathologic Characteristics for Predicting Treatment Response in Rheumatoid Arthritis

Kim, K.-J.; Kim, M.; Tagkopolous, I.

10.1101/279786 — bioinformatics — Posted on 2018-03-10

1451 Identification of cyclic hexapeptides natural products with inhibitory potency against Mycobacterium tuberculosis

Singh, S. B.; Odingo, J.; Bailey, M. A.; Sunde, B.; Korkegian, A.; O'Malley, T.; Ovechkina, Y.; Ioerger, T. R.; Sacchettini, J. C.; Young, K.; Olsen, D. B.; Parish, T.

10.1101/279307 — microbiology — Posted on 2018-03-10

1452 Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Walters, R. K.; Adams, M. J.; Adkins, A. E.; Aliev, F.; Bacanu, S.-A.; Batzler, A.; Bertelsen, S.; Biernacka, J.; Bigdeli, T. B.; Chen, L.-S.; Clarke, T.-K.; Chou, Y.-L.; Degenhardt, F.; Docherty, A. R.; Fontanillas, P.; Foo, J.; Fox, L.; Frank, J.; Giegling, I.; Gordon, S.; Hack, L.; -, ; Hartz, S. M.; Heilmann-Heimbach, S.; Herms, S.; Hodgkinson, C.; Hoffmann, P.; Hottenga, J.-J.; Kennedy, M. A.; Alanne-Kinnunen, M.; Konte, B.; Lahti, J.; Lahti-Pulkkinen, M.; Ligthart, L.; Loukola, A.-M.; Maher, B. S.; Mbarek, H.; McIntosh, A. M.; McQueen, M. B.; Milaneschi, Y.; Palviainen, T.; Pearson, J.

10.1101/257311 — genetics — Posted on 2018-03-10

1453 A general framework for predicting the transcriptomic consequences of non-coding variation

Abdalla, M.; Abdalla, M.; McCarthy, M. I.; Holmes, C. C.

10.1101/279323 — genetics — Posted on 2018-03-10

1454 Drosophila egg-derived tyrosine phosphatase (EDTP): a novel target for improved survivorship to prolonged anoxia and cellular protein aggregates

Xiao, C.; Qiu, S.; Li, X.; Luo, D.-J.; Robertson, R. M.; Liu, G.-P.

10.1101/279885 — genetics — Posted on 2018-03-10

1455 Excitatory TMS Boosts Memory Representations

Wang, W.-C.; Wing, E.; Murphy, D. L. K.; Luber, B.; Lisanby, S. H.; Cabeza, R.; Davis, S. W.

10.1101/279547 — neuroscience — Posted on 2018-03-10

1456 Serotonin signaling in hippocampus during initial cocaine abstinence drives persistent drug seeking

Kohtz, A. S.; Aston-Jones, G.

10.1101/279729 — neuroscience — Posted on 2018-03-10

1457 Expectations may Influence the Effects of Transcranial Direct-Current Stimulation

Rabipour, S.; Wu, A. D.; Davidson, P. S. R.; Iacoboni, M.

10.1101/279554 — neuroscience — Posted on 2018-03-10

1458 Evaluation of Caulobacter crescentus strain fitness at the genomic scale during growth in natural freshwater

Hentchel, K. L.; Reyes Ruiz, L. M.; Fiebig, A.; Curtis, P. D.; Coleman, M. L.; Crosson, S.

10.1101/279711 — microbiology — Posted on 2018-03-10

1459 Assessment of the petroleum hydrocarbon biodegradation potential of the sediment microbial community from an urban fringing tidal marsh of Northern New England.

Ni Chadhain, S. M.; Miller, J. L.; Dustin, J. P.; Trethewey, J. P.; Jones, S. H.; Launen, L.

10.1101/279760 — microbiology — Posted on 2018-03-10

1460 Chromatin accessibility dynamics across C. elegans development and ageing

Janes, J.; Dong, Y.; Schoof, M.; Serizay, J.; Appert, A.; Cerrato, C.; Woodbury, C.; Chen, R.; Gemma, C.; Huang, N.; Kissiov, D.; Stempor, P.; Steward, A.; Zeiser, E.; Sauer, S.; Ahringer, J.

10.1101/279158 — genomics — Posted on 2018-03-10

1461 The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence

Meisel, R. P.; Wexler, J. R.

10.1101/279737 — genomics — Posted on 2018-03-10

1462 Expanding an expanded genome: long-read sequencing of Trypanosoma cruzi

Berna, L.; Rodriguez, M.; Chiribao, M. L.; Parodi-Talice, A.; Pita, S.; Rijo, G.; Alvarez-Valin, F.; Robello, C.

10.1101/279174 — genomics — Posted on 2018-03-10

1463 Ancient genomes document multiple waves of migration in Southeast Asian prehistory

Lipson, M.; Cheronet, O.; Mallick, S.; Rohland, N.; Oxenham, M.; Pietrusewsky, M.; Pryce, T. O.; Willis, A.; Matsumura, H.; Buckley, H.; Domett, K.; Nguyen, G. H.; Trinh, H. H.; Kyaw, A. A.; Win, T. T.; Pradier, B.; Broomandkhoshbacht, N.; Candilio, F.; Changmai, P.; Fernandes, D.; Ferry, M.; Gamarra, B.; Harney, E.; Kampuansai, J.; Kutanan, W.; Michel, M.; Novak, M.; Oppenheimer, J.; Sirak, K.; Stewardson, K.; Zhang, Z.; Flegontov, P.; Pinhasi, R.; Reich, D.

10.1101/279646 — genetics — Posted on 2018-03-10

1464 Label-free imaging of cholesterol and lipid distributions in model membranes

Donaldson, S. H.; de Aguiar, H. B.

10.1101/279794 — biophysics — Posted on 2018-03-10

1465 Single-step Enzymatic Glycoengineering for the Construction of Antibody-cell Conjugates

Li, J.; Chen, M.; Liu, Z.; Zhang, L.; Felding, B. H.; Lauvau, G.; Abadier, M.; Ley, K.; Wu, P.

10.1101/279240 — bioengineering — Posted on 2018-03-10

1466 Thioredoxins induce oocyte maturation in holothuroids (Echinodermata)

Leonet, A.; Delroisse, J.; Schuddinck, C.; Wattiez, R.; Jangoux, M.; Eeckhaut, I.

10.1101/279273 — zoology — Posted on 2018-03-10

1467 Post-mortem T2*- weighted MRI imaging of cortical iron reflects severity of Alzheimer’s Disease

Bulk, M.; Kenkhuis, B.; van der Graaf, L. M.; Goeman, J. J.; Natte, R.; van der Weerd, L.

10.1101/279513 — neuroscience — Posted on 2018-03-10

1468 Shared Polygenicity detection using Elastic Nets: SHARPEN

John, M.; Lencz, T.

10.1101/279604 — genetics — Posted on 2018-03-10

1469 Aligning functional network constraint to evolutionary outcomes

Wollenberg Valero, K.

10.1101/278663 — evolutionary biology — Posted on 2018-03-10

1470 Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) motifs

Alam, T.; Alazmi, M.; Naser, R.; Huser, F.; Momin, A. A.; Walkiewicz, K. W.; Canlas, C. G.; Huser, R. G.; Ali, A.; Merzaban, J.; Bajic, V. B.; Gao, X.; Arold, S. T.

10.1101/278903 — bioinformatics — Posted on 2018-03-10

1471 BioFeatureFinder: Flexible, unbiased analysis of biological characteristics associated with genomic regions

Massirer, K. B.; Ciamponi, F. E.; Lovci, M. T.

10.1101/279612 — bioinformatics — Posted on 2018-03-10

1472 25 Years of Molecular Biology Databases: A Study of Proliferation, Impact, and Maintenance

Imker, H. J.

10.1101/279067 — molecular biology — Posted on 2018-03-09

1473 An important class of intron retention events in human erythroblasts is regulated by cryptic exons proposed to function as splicing decoys

Parra, M.; Booth, B. W.; Weiszmann, R.; Yee, B. A.; Yeo, G. W.; Brown, J. B.; Celniker, S. E.; Conboy, J. G.

10.1101/258897 — molecular biology — Posted on 2018-03-09

1474 A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain

Kleaveland, B.; Shi, C. Y.; Stefano, J.; Bartel, D. P.

10.1101/279687 — molecular biology — Posted on 2018-03-09

1475 Analog closed-loop modulation of hippocampal pyramidal cells dissociates gamma frequency and amplitude

Nicholson, E.; Kuzmin, D.; Leite, M.; Akam, T. E.; Kullmann, D. M.

10.1101/279588 — neuroscience — Posted on 2018-03-09

1476 KCC2 overexpression prevents the paradoxical seizure-promoting action of somatic inhibition

Magloire, V.; Cornford, J. H.; Lieb, A.; Kullmann, D. M.; Pavlov, I.

10.1101/279539 — neuroscience — Posted on 2018-03-09

1477 Telomere-loop dynamics in chromosome end protection

Van Ly, D.; Low, R. R. J.; Frölich, S.; Bartolec, T. K.; Kafer, G. R.; Pickett, H. A.; Gaus, K.; Cesare, A. J.

10.1101/279877 — molecular biology — Posted on 2018-03-09

1478 SESCA: Predicting the Circular Dichroism Spectra of Proteins from Molecular Structure

Nagy, G.; Hoffmann, S. V.; Jones, N. C.; Grubmuller, H.

10.1101/279752 — biophysics — Posted on 2018-03-09

1479 GetOrganelle: a simple and fast pipeline for de novo assembly of a complete circular chloroplast genome using genome skimming data

Jin, J.-J.; Yu, W.-B.; Yang, J.-B.; Song, Y.; Yi, T.-S.; Li, D.-Z.

10.1101/256479 — bioinformatics — Posted on 2018-03-09

1480 Quantifying how constraints limit the diversity of viable routes to adaptation

Yeaman, S.; Gerstein, A. C.; Hodgins, K. A.; Whitlock, M. C.

10.1101/279661 — evolutionary biology — Posted on 2018-03-09

1481 KLF6 and STAT3 co-occupy regulatory DNA and functionally synergize to promote axon growth in CNS neurons

Wang, Z.; Mehra, V.; Simpson, M.; Maunze, B.; Eastwood, E.; Holan, L.; Blackmore, M.; Venkatesh, I.

10.1101/257022 — neuroscience — Posted on 2018-03-09

1482 Efficient computation of co-transcriptional RNA-ligand interaction dynamics

Wolfinger, M. T.; Flamm, C.; Hofacker, I. L.

10.1101/248450 — bioinformatics — Posted on 2018-03-09

1483 Does force-field adaptation induce after-effects on space representation?

Michel, C.; Bonnetain, L.; White, O.

10.1101/238246 — neuroscience — Posted on 2018-03-09

1484 Predicting protein targets for drug-like compounds using transcriptomics

Pabon, N. A.; Xia, Y.; Estabrooks, S. K.; Ye, Z.; Herbrand, A. K.; Sub, E.; Biondi, R. M.; Assimon, V. A.; Gestwicki, J. E.; Brodsky, J. L.; Camacho, C. J.; Bar-Joseph, Z.

10.1101/254367 — genomics — Posted on 2018-03-09

1485 Adaptive evolution within the gut microbiome of individual people

Zhao, S.; Lieberman, T. D.; Poyet, M.; Groussin, M.; Gibbons, S. M.; Xavier, R. J.; Alm, E. J.

10.1101/208009 — evolutionary biology — Posted on 2018-03-09

1486 Conserved patterns of somatic mutations in human blood cells

Liggett, L. A.; Sharma, A.; De, S.; DeGregori, J.

10.1101/208066 — genetics — Posted on 2018-03-09

1487 Habitat preference of an herbivore shapes the habitat distribution of its host plant

Alexandre, N. M.; Humphrey, P. T.; Gloss, A. D.; Lee, J.; Frazier, J.; Affeldt, H. A.; Whiteman, N. K.

10.1101/156240 — ecology — Posted on 2018-03-09

1488 Mixed Effects Association of Single Cells Identifies an Expanded Th1-Skewed Cytotoxic Effector CD4+ T Cell Subset in Rheumatoid Arthritis

Fonseka, C. Y.; Rao, D. A.; Teslovich, N. C.; Korsunsky, I.; Hannes, S. K.; Slowikowski, K.; Gurish, M. F.; Donlin, L. T.; Weinblatt, M. E.; Massarotti, E. M.; Coblyn, J. S.; Helfgott, S. M.; Todd, D. J.; Bykerk, V. P.; Karlson, E. W.; Ermann, J.; Lee, Y. C.; Brenner, M. B.; Raychaudhuri, S.

10.1101/172403 — bioinformatics — Posted on 2018-03-09

1489 Do adolescents take more risks? Not when facing a novel uncertain situation

Elteto, N.; Janacsek, K.; Kobor, A.; Takacs, A.; Toth-Faber, E.; Nemeth, D.

10.1101/206128 — neuroscience — Posted on 2018-03-09

1490 Characterization of Diverse Homoserine Lactone Synthases in Escherichia coli

Daer, R.; Barrett, C.; Melendez, E. L.; Wu, J.; Tekel, S.; Xu, J.; Dennison, B.; Muller, R.; Haynes, K. A.

10.1101/279349 — synthetic biology — Posted on 2018-03-09

1491 Dendritic NMDA receptors in parvalbumin neurons enable strong and stable neuronal assemblies

Cornford, J. H.; Mercier, M. S.; Leite, M.; Magloire, V.; Häusser, M.; Kullmann, D. M.

10.1101/279505 — neuroscience — Posted on 2018-03-09

1492 The territory of my body: Testosterone prevents limb cooling in the Rubber Hand Illusion

van der Westhuizen, D.; Page, T.; Solms, M.; van Honk, J.

10.1101/279463 — neuroscience — Posted on 2018-03-09

1493 Effect of tributyltin chloride (TBT-Cl) exposure on expression of HSP90β1 in the river pufferfish (Takifugu obscurus): evidences for its immunologic function involving in exploring process

Xu, D.-p.; Fang, D.-a.; Zhao, C.-s.; Jiang, S.-l.; Hu, H.-Y.

10.1101/279331 — immunology — Posted on 2018-03-09

1494 Assessing macrophyte seasonal dynamics using dense time series of medium resolution satellite data

Villa, P.; Pinardi, M.; Bolpagni, R.; Zinke, P.; Nedelcut, F.; Bresciani, M.

10.1101/279448 — ecology — Posted on 2018-03-09

1495 Experimental manipulation of nocturnal nest cavity temperature in wild blue tits

Simmonds, E. G.; Sheldon, B. C.; Coulson, T.; Cole, E. F.

10.1101/279455 — ecology — Posted on 2018-03-09

1496 Experimental loss of generalist plants reveals alterations in plant-pollinator interactions and a constrained flexibility of foraging

Biella, P.; Akter, A.; Ollerton, J.; Tarrant, S.; Janecek, S.; Jersakova, J.; Klecka, J.

10.1101/279430 — ecology — Posted on 2018-03-09

1497 Effect of 5-trans isomer of arachidonic acid on model liposomal membranes studied by a combined simulation and experimental approach

Tremi, I.; Anagnostopoulos, D.; Spyratou, E.; Gkeka, P.; Georgakilas, A.; Chatgilialoglu, C.; Cournia, Z.

10.1101/279422 — biophysics — Posted on 2018-03-09

1498 Shoelaces: an interactive tool for ribosome profiling processing and visualization

Birkeland, A.; Chyzynska, K.; Valen, E.

10.1101/279497 — bioinformatics — Posted on 2018-03-09

1499 Contribution of structural variation to genome structure: TAD fusion discovery and ranking

Huynh, L.; Hormozdiari, F.

10.1101/279356 — bioinformatics — Posted on 2018-03-09

1500 Structure of the 30S ribosomal decoding complex at ambient temperature

Dao, E. H.; Poitevin, F.; Sierra, R. G.; Gati, C.; Rao, Y.; Ciftci, H. I.; Aksit, F.; McGurk, A.; Obrinski, T.; Mgbam, P.; Hayes, B.; de Lichtenberg, C.; Pardo-Avila, F.; Corsepius, N.; Zhang, L.; Seaberg, M.; Hunter, M. S.; Liang, M.; Koglin, J. E.; Wakatsuki, S.; DeMirci, H.

10.1101/262972 — biophysics — Posted on 2018-03-09

1501 Neural coding of leg proprioception in Drosophila

Mamiya, A.; Gurung, P.; Tuthill, J.

10.1101/274498 — neuroscience — Posted on 2018-03-09

1502 Dynamic integration of multisensory turn commands supports active reorienting during ongoing navigation.

Currier, T. A.; Nagel, K. I.

10.1101/273805 — neuroscience — Posted on 2018-03-09

1503 Big data approaches to decomposing heterogeneity across the autism spectrum

Lombardo, M. V.; Lai, M.-C.; Baron-Cohen, S.

10.1101/278788 — neuroscience — Posted on 2018-03-09

1504 Temperature is a key driver of a wildlife epidemic and future warming will increase impacts

Price, S. J.; Leung, W. T.; Owen, C.; Sergeant, C.; Cunningham, A. A.; Balloux, F.; Garner, T. W.; Nichols, R. A.

10.1101/272369 — epidemiology — Posted on 2018-03-09

1505 Optimizing Disease Surveillance by Reporting on the Blockchain

Coelho, F. C.

10.1101/278473 — epidemiology — Posted on 2018-03-09

1506 Interaction of diabetes and smoking on stroke: A population-based cross-sectional survey in China

Heqing, L.; Zongmei, D.; Pan, Z.; Xiaoping, S.; Ting, L.; Chunyan, Z.; Xunbao, Z.; Peian, L.

10.1101/277293 — epidemiology — Posted on 2018-03-09

1507 An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936.

Hamilton, O. K.; Zhang, Q.; McRae, A. F.; Walker, R. M.; Morris, S. W.; Redmond, P.; Campbell, A.; Murray, A. D.; Porteous, D. J.; Evans, K. L.; McIntosh, A. M.; Deary, I. J.; Marioni, R. E.

10.1101/278234 — epidemiology — Posted on 2018-03-09

1508 Boosting Diabetes and Pre-Diabetes Screening in Rural Ghana via Mobile Phones Apps

Crimi, A.; Nyarko, B. E.; Amoah, R. S.

10.1101/278960 — epidemiology — Posted on 2018-03-09

1509 Zika Virus Outbreak, Barbados, 2015 - 2016

Ryan, S. J.; Lippi, C. A.; Carlson, C. J.; Stewart-Ibarra, A. M.; Borbor Cordova, M. J.; Romero, M. M.; Cox, S.-A.; Mahon, R.; Trotman, A.; Rollock, L.; Gittens-St. Hilaire, M.; King, D.; Daniel, S.

10.1101/279182 — epidemiology — Posted on 2018-03-09

1510 A nuclear hormone receptor and lipid metabolism axis are required for the maintenance and regeneration of reproductive organs

Zhang, S.; Guo, L.; Guerrero-Hernandez, C.; Ross, E. J.; Gotting, K.; McKinney, S. A.; Wang, W.; Xiang, Y.; Hawley, R. S.; Sanchez Alvarado, A.

10.1101/279364 — developmental biology — Posted on 2018-03-09

1511 Neck muscle spindle noise biases reaches in a multi-sensory integration task

Abedi Khoozani, P.; Blohm, G.

10.1101/182907 — neuroscience — Posted on 2018-03-09

1512 vqtl: An R package for Mean-Variance QTL Mapping

Corty, R. W.; Valdar, W.

10.1101/149377 — genetics — Posted on 2018-03-09

1513 Entrainment of theta, not alpha, oscillations is predictive of the brightness enhancement of a flickering stimulus

Bertrand, J. K.; Wispinski, N. J.; Mathewson, K. E.; Chapman, C. S.

10.1101/239061 — neuroscience — Posted on 2018-03-09

1514 Progesterone receptor maintains estrogen receptor gene expression by regulating DNA methylation in hormone-free breast cancer cells

Verde, G.; De Llobet, L. I.; Wright, R. H. G.; Quilez, J.; Peiro, S.; Le Dily, F.; Beato, M.

10.1101/192567 — molecular biology — Posted on 2018-03-09

1515 Early Holocene Morphological Variation in Hunter-Gatherer Hands and Feet

Hoover, K. C.; Berbesque, J. C.

10.1101/271460 — evolutionary biology — Posted on 2018-03-09

1516 Transcription-driven Chromatin Repression of Intragenic Promoters

Nielsen, M.; Ard, R.; Leng, X.; Ivanov, M.; Kindgren, P.; Pelechano, V.; Marquardt, S.

10.1101/279414 — genomics — Posted on 2018-03-09

1517 A genome-wide scan for correlated mutations detects macromolecular and chromatin loop interactions in Arabidopsis thaliana.

Perlaza-Jimenez, L.; Walther, D.

10.1101/279489 — genomics — Posted on 2018-03-09

1518 Longitudinal single cell fate in hematopoiesis in vivo using cellular barcoding and DiSNE movie visualization

Gao, J.; Lin, D.; Crampin, E.; Naik, S.

10.1101/279406 — developmental biology — Posted on 2018-03-09

1519 Dynamic Kinetochore Size Regulation Promotes Microtubule Capture And Chromosome Biorientation In Mitosis

Sacristan, C.; Ahmad, M.; Keller, J.; Fermie, J.; Groenewold, V.; Tromer, E.; Fish, A.; Melero, R.; Carazo, J. M.; Klumperman, J.; Musacchio, A.; Perrakis, A.; Kops, G. J.

10.1101/279398 — cell biology — Posted on 2018-03-09

1520 The Invisible Maze Task (IMT): Interactive Exploration of Sparse Virtual Environments to Investigate Action-Driven Formation of Spatial Representations

Gehrke, L.; Iversen, J. R.; Makeig, S.; Gramann, K.

10.1101/278283 — neuroscience — Posted on 2018-03-09

1521 DECODE-ing sparsity patterns in single-cell RNA-seq

Mohammadi, S.; Davila-Velderrain, J.; Kellis, M.; Grama, A.

10.1101/241646 — bioinformatics — Posted on 2018-03-09

1522 Dynamics of corticospinal motor control during overground and treadmill walking in humans

Roeder, L.; Boonstra, T. W.; Smith, S. S.; Kerr, G. K.

10.1101/177915 — physiology — Posted on 2018-03-09

1523 Genome sequencing reveals that Streptococcus pneumoniae possesses a large and diverse repertoire of antimicrobial toxins

Rezaei Javan, R.; van Tonder, A. J.; King, J. P.; Harrold, C. L.; Brueggemann, A. B.

10.1101/203398 — genomics — Posted on 2018-03-09

1524 A computational model of shared fine-scale structure in the human connectome

Guntupalli, J. S.; Ma, F.; Haxby, J. V.

10.1101/108738 — neuroscience — Posted on 2018-03-09

1525 ShapeRotator: an R tool for standardised rigid rotations of articulated Three-Dimensional structures with application for geometric morphometrics

Vidal-Garcia, M.; Bandara, L.; Keogh, J. S.

10.1101/159392 — evolutionary biology — Posted on 2018-03-09

1526 Lipid droplet phase transition in freezing cat embryos and oocytes probed by Raman spectroscopy

Okotrub, K. A.; Mokrousova, V. I.; Amstislavsky, S. Y.; Surovtsev, N. V.

10.1101/275164 — biophysics — Posted on 2018-03-09

1527 A strategy to study intrinsically mixed folded proteins: The structure in solution of ataxin-3

Sicorello, A.; Kelly, G.; Oregioni, A.; Novacek, J.; sklenar, v.; Pastore, A.

10.1101/275131 — biophysics — Posted on 2018-03-09

1528 Take ACTION to characterize the functional identity of single cells

Mohammadi, S.; Ravindra, V.; Gleich, D.; Grama, A.

10.1101/081273 — bioinformatics — Posted on 2018-03-09

1529 A nuclear hormone receptor and lipid metabolism axis are required for the maintenance and regeneration of reproductive organs

Zhang, S.; Guo, L.; Guerrero-Hernandez, C.; Ross, E. J.; Gotting, K.; McKinney, S. A.; Wang, W.; Xiang, Y.; Hawley, R. S.; Sanchez Alvarado, A.

10.1101/279364 — developmental biology — Posted on 2018-03-09

1530 Zebrafish as a model to investigate the effects of exercise in cancer

Yin, A.; Campbell, N. R.; Jones, L. W.; White, R. M.

10.1101/279232 — cancer biology — Posted on 2018-03-09

1531 Conformational flexibility of collagen molecules: composition and environmental effects

Rezaei, N.; Lyons, A.; Forde, N.

10.1101/279380 — biophysics — Posted on 2018-03-09

1532 Conformational regulation of proteolysis in the extracellular matrix receptor dystroglycan

Hayward, A. N.; Gordon, W. R.

10.1101/279315 — cell biology — Posted on 2018-03-09

1533 Investigating established EEG parameter during real-world driving

Protzak, J.; Gramann, K.

10.1101/275396 — neuroscience — Posted on 2018-03-08

1534 NeuroMTL iSEG challenge methods

Fonov, V.; Doyle, A.; Evans, A. C.; Collins, D. L.

10.1101/278465 — neuroscience — Posted on 2018-03-08

1535 Differentiation of Alzheimer’s disease based on local and global parameters in personalized Virtual Brain models

Zimmermann, J.; Perry, A.; Breakspear, M.; Schirner, M.; Sachdev, P.; Wen, W.; Kochan, N.; Mapstone, M.; Ritter, P.; McIntosh, A. R.; Solodkin, A.

10.1101/277624 — neuroscience — Posted on 2018-03-08

1536 Multi-study inference of regulatory networks for more accurate models of gene regulation

Castro, D. M.; de Veaux, N.; Miraldi, E. R.; Bonneau, R.

10.1101/279224 — systems biology — Posted on 2018-03-08

1537 Multi-Link Analysis: Brain Network Comparison via Sparse Connectivity Analysis

Crimi, A.; Giancadro, L.; Sambataro, F.; Gozzi, A.; Murino, V.; Sona, D.

10.1101/277046 — neuroscience — Posted on 2018-03-08

1538 Insights into circovirus host range from the genomic fossil record.

Dennis, T. P. W.; Flynn, P. J.; De Souza, W. M.; Singer, J. B.; Moreau, C.; Wilson, S. J.; Gifford, R. J.

10.1101/246777 — microbiology — Posted on 2018-03-08

1539 Mobile genetic element-encoded hypertolerance to copper protects Staphylococcus aureus from killing by host phagocytes

Zapotoczna, M.; Pelicioli-Riboldi, G.; Moustafa, A.; Dickson, E.; Narechania, A.; Morrissey, J.; Planet, P.; Holden, M. T.; Waldron, K.; Geoghegan, J.

10.1101/279000 — microbiology — Posted on 2018-03-08

1540 Harbour seals are regaining top-down control in a coastal ecosystem

Aarts, G.; Brasseur, S.; Poos, J. J.; Schop, J.; Kirkwood, R.; van Kooten, T.; Mul, E.; Reijnders, P.; Rijnsdorp, A. D.; Tulp, I.

10.1101/267567 — ecology — Posted on 2018-03-08

1541 Transition from actin-driven to water-driven cell migration depends on external hydraulic resistance

Li, Y.; Sun, S. X.

10.1101/275123 — cell biology — Posted on 2018-03-08

1542 Monomeric streptavidin: a versatile regenerative handle for force spectroscopy

Bauer, M. S.; Milles, L. F.; Sedlak, S. M.; Gaub, H. E.

10.1101/276444 — biophysics — Posted on 2018-03-08

1543 A Hidden Markov Model for Detecting Confinement in Single Particle Tracking Trajectories

Slator, P. J.; Burroughs, N.

10.1101/275107 — biophysics — Posted on 2018-03-08

1544 Labels of aberrant Clusters of Differentiation gene expression in a compendium of systemic lupus erythematosus patients

Le, T. T.; Blackwood, N. O.; Breitenstein, M. K.

10.1101/277145 — bioinformatics — Posted on 2018-03-08

1545 The Invisible Maze Task (IMT): Interactive Exploration of Sparse Virtual Environments to Investigate Action-Driven Formation of Spatial Representations

Gehrke, L.; Iversen, J. R.; Makeig, S.; Gramann, K.

10.1101/278283 — neuroscience — Posted on 2018-03-08

1546 Organ-specific translation elongation rates measured by in vivo ribosome profiling

Gerashchenko, M. V.; Peterfi, Z.; Gladyshev, V. N.

10.1101/279257 — molecular biology — Posted on 2018-03-08

1547 Species- and C-terminal linker-dependent variations in the dynamic behavior of FtsZ on membranes in vitro

Sundararajan, K.; Vecchiarelli, A. G.; Mizuuchi, K.; Goley, E.

10.1101/278564 — microbiology — Posted on 2018-03-08

1548 Gut microbiota density influences host physiology and is shaped by host and microbial factors

Contijoch, E.; Britton, G. J.; Yang, C.; Mogno, I.; Li, Z.; Ng, R.; Llewellyn, S. R.; Hira, S.; Johnson, C.; Rabinowitz, K. M.; Barkan, R.; Dotan, I.; Hirten, R. P.; Fu, S.-C.; Luo, Y.; Yang, N.; Luong, T.; Labrias, P. R.; Lira, S.; Peter, I.; Grinspan, A.; Clemente, J. C.; Kosoy, R.; Kim-Schulze, S.; Qin, X.; Castillo, A.; Hurley, A.; Atreja, A.; Rogers, J.; Fasihuddin, F.; Saliaj, M.; Nolan, A.; Reyes-Mercedes, P.; Rodriguez, C.; Aly, S.; Santa-Cruz, K.; Peters, L. A.; Suarez-Farinas, M.; Huang, R.; Hao, K.; Zhu, J.; Zhang, B.; Losic, B.; Irizar, H.; Song, W.-M.; Di Narzo, A.; Wang, W.; Cohe

10.1101/277095 — microbiology — Posted on 2018-03-08

1549 Magnesium increases homoeologous crossover frequency in ZIP4 (Ph1) mutant wheat-wild relative hybrids

Rey, M.-D.; Martin, A. C.; Smedley, M.; Hayta, S.; Harwood, W.; Shaw, P.; Moore, G.

10.1101/278341 — cell biology — Posted on 2018-03-08

1550 Effect of chromatin flexibility on diffusive loop extrusion via molecular slip-links

Brackley, C. A.; Johnson, J.; Michieletto, D.; Marenduzzo, D.

10.1101/275214 — biophysics — Posted on 2018-03-08

1551 Coupling magnetically induced electric fields to neurons: longitudinal and transverse activation

Wang, B.; Grill, W. M.; Peterchev, A. V.

10.1101/275073 — bioengineering — Posted on 2018-03-08

1552 Behavioral phenotyping of an improved mouse model of Phelan-McDermid Syndrome with a complete deletion of the Shank3 gene

Drapeau, E.; Riad, M.; Kajiwara, Y.; Buxbaum, J. D.

10.1101/278622 — animal behavior and cognition — Posted on 2018-03-08

1553 A streamlined method for transposon mutagenesis of Rickettsia parkeri yields numerous mutations that impact infection

Lamason, R. L.; Kafai, N. M.; Welch, M. D.

10.1101/277160 — microbiology — Posted on 2018-03-08

1554 Whole genome sequencing reveals the emergence of a Pseudomonas aeruginosa shared strain sub-lineage among patients treated within a single cystic fibrosis centre

Wee, B. A.; Tai, A. S.; Sherrard, L. J.; Ben Zakour, N. L.; Hanks, K. R.; Kidd, T. J.; Ramsay, K. A.; Lamont, I.; Whiley, D. M.; Bell, S. C.; Beatson, S. A.

10.1101/261586 — genomics — Posted on 2018-03-08

1555 Bacteriophage cooperation suppresses CRISPR-Cas3 and Cas9 immunity

Borges, A. L.; Zhang, J. Y.; Rollins, M.; Osuna, B. A.; Wiedenheft, B.; Bondy-Denomy, J.

10.1101/279141 — microbiology — Posted on 2018-03-08

1556 The Hedgehog signaling domain was acquired from a prokaryote.

Roelink, H.

10.1101/276295 — evolutionary biology — Posted on 2018-03-08

1557 Selection removes Shine-Dalgarno-like sequences from within protein coding genes

Hockenberry, A. J.; Amaral, L. A.; Jewett, M. C.; Wilke, C. O.

10.1101/278689 — evolutionary biology — Posted on 2018-03-08

1558 Tolerogenic transcriptome landscape in CD8+ T lymphocytes after exposure to erythrocyte-targeted antigens

Grimm, A.; Gobet, C.; Diaceri, G.; Quaglia-Thermes, X.; Hubbell, J.

10.1101/278457 — immunology — Posted on 2018-03-08

1559 Adhesion of active cytoskeletal vesicles

Maan, R.; Loiseau, E.; Bausch, A.

10.1101/275115 — biophysics — Posted on 2018-03-08

1560 Presurgical language fMRI: Current technical practices in epilepsy surgical planning

Benjamin, C. F. A.; Dhingra, I.; Li, A.; Blumenfeld, H.; Alkawadri, R.; Bickel, S.; Helmstaedter, C.; Meletti, S.; Bronen, R. A.; Warfield, S. K.; Peters, J. M.; Reutens, D.; Polczynska, M. M.; Hirsch, L. J.; Spencer, D. D.

10.1101/279117 — neuroscience — Posted on 2018-03-08

1561 Alzheimer’s environmental and genetic risk scores are differentially associated with ‘g’ and δ

Andrews, S. J.; McFall, G. P.; Dixon, R. A.; Cherbuin, N.; Eramudugolla, R.; Anstey, K. J.

10.1101/279018 — genetics — Posted on 2018-03-08

1562 Volvox barberi flocks, forming near-optimal, two-dimensional, polydisperse lattice packings

Balasubramanian, R.

10.1101/279059 — biophysics — Posted on 2018-03-08

1563 OMCD: OncoMir Cancer Database

Sarver, A.; Sarver, A.; Yuan, C.; Subramanian, S.

10.1101/279125 — bioinformatics — Posted on 2018-03-08

1564 Subject-specificity of the correlation between large-scale structural and functional connectivity

Zimmermann, J.; Griffiths, J.; Schirner, M.; Ritter, P.; McIntosh, A. R.

10.1101/277590 — neuroscience — Posted on 2018-03-08

1565 Anti-CRISPR phages cooperate to overcome CRISPR-Cas immunity

Landsberger, M.; Gandon, S.; Meaden, S.; Chabas, H.; Buckling, A.; Westra, E. R.; van Houte, S.

10.1101/279026 — microbiology — Posted on 2018-03-08

1566 Increased susceptibility to intracellular bacteria and immunopathology driven by a dysregulated macrophage response to TNF

Bhattacharya, B.; Chatterjee, S.; Berland, R.; Pichugin, A.; Gao, Y.; Ivanov, A.; Connor, J. H.; Yan, B.-S.; Kobzik, L.; Kramnik, I.

10.1101/238873 — immunology — Posted on 2018-03-08

1567 Extraction of a recombinant full-length NADPH-cytochrome P450 oxidoreductase from bacterial membranes: effect of detergents and additives

Arafeh, S.; Galiakhmetov, A.; Kovrigina, E.; Fellin, E.; Kovrigin, E.

10.1101/279216 — biochemistry — Posted on 2018-03-08

1568 Improved genome assembly and annotation for the rock pigeon (Columba livia)

Holt, C.; Campbell, M.; Keays, D.; Edelman, N.; Kapusta, A.; Maclary, E.; Domyan, E.; Suh, A.; Warren, W.; Yandell, M.; Gilbert, T.; Shapiro, M. D.

10.1101/220947 — genomics — Posted on 2018-03-08

1569 Proof of concept continuous event logging in living cells

Shur, A.; Murray, R. M.

10.1101/225151 — synthetic biology — Posted on 2018-03-08

1570 Decoding of neural data using cohomological learning

Rybakken, E.; Baas, N.; Dunn, B.

10.1101/222331 — neuroscience — Posted on 2018-03-08

1571 A generalization of the informational view of non-random mating: Models with variable population frequencies

Carvajal-Rodriguez, A.

10.1101/279075 — evolutionary biology — Posted on 2018-03-08

1572 Cost of resistance: an unreasonably expensive concept

Lenormand, T.; Harmand, N.; Gallet, R.

10.1101/276675 — evolutionary biology — Posted on 2018-03-08

1573 Improvement of the memory function by negative autoregulation of a mutual repression network in a stochastic environment

Hasan, A. B. M. S. U.; Kurata, H.; Pechmann, S.

10.1101/279109 — systems biology — Posted on 2018-03-08

1574 Comparison of feature representations in MRI-based MCI-to-AD conversion prediction

Gomez-Sancho, M.; Tohka, J.; Gomez-Verdejo, V.

10.1101/213132 — neuroscience — Posted on 2018-03-08

1575 Genetic interactions between the chromosome axis-associated protein Hop1 and homologous recombination determinants in Schizosaccharomyces pombe

Brown, S. D.; Jarosinska, O. D.; Lorenz, A.

10.1101/190439 — genetics — Posted on 2018-03-08

1576 Striatal cholinergic receptor activation causes a rapid, selective, & state-dependent rise in corticostriatal β activity.

Pittman-Polletta, B. R.; Quach, A.; Mohammed, A. I.; Romano, M.; Kondabolou, K.; Kopell, N. J.; Han, X.; McCarthy, M. M.

10.1101/148551 — neuroscience — Posted on 2018-03-08

1577 Biogeography & environmental conditions shape bacteriophage-bacteria networks across the human microbiome

Hannigan, G. D.; Duhaime, M. B.; Koutra, D.; Schloss, P. D.

10.1101/144642 — microbiology — Posted on 2018-03-08

1578 Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in a homogeneous microbial population of fixed size

Marrec, L.; Bitbol, A.-F.

10.1101/279091 — evolutionary biology — Posted on 2018-03-08

1579 Enhancing coevolution-based contact prediction by imposing structural self-consistency of the contacts

Kassem, M. M.; Christoffersen, L. B.; Cavalli, A.; Lindorff-Larsen, K.

10.1101/279190 — bioinformatics — Posted on 2018-03-08

1580 Effect size and statistical power in the rodent fear conditioning literature - a systematic review

Carneiro, C. F. D.; Moulin, T. C.; Macleod, M. R.; Amaral, O. B.

10.1101/116202 — neuroscience — Posted on 2018-03-08

1581 Posterior and Mid-Fusiform Contribute to Distinct Stages of Facial Expression Processing

Li, Y.; Richardson, R. M.; Ghuman, A. S.

10.1101/279166 — neuroscience — Posted on 2018-03-08

1582 SAVER: Gene expression recovery for UMI-based single cell RNA sequencing

Huang, M.; Wang, J.; Torre, E.; Dueck, H.; Shaffer, S.; Bonasio, R.; Murray, J.; Raj, A.; Li, M.; Zhang, N. R.

10.1101/138677 — genomics — Posted on 2018-03-08

1583 Inferring the shape of global epistasis

Otwinowski, J.; McCandlish, D. M.; Plotkin, J.

10.1101/278630 — evolutionary biology — Posted on 2018-03-08

1584 A theoretical high-density nanoscopy study leads to the design of UNLOC, an unsupervised algorithm

Mailfert, S.; Touvier, J.; Benyoussef, L.; Fabre, R.; Rabaoui, A.; Blache, M.-C.; Hamon, Y.; Brustlein, S.; Monneret, S.; Bertaux, N.; Marguet, D. A.

10.1101/275313 — biophysics — Posted on 2018-03-08

1585 Na/K pump: Single-channel vs. Two-access-channel

Chen, W.

10.1101/275263 — biophysics — Posted on 2018-03-08

1586 Direct Evidence of Effect of Glycerol on Hydration and Helix-to-Sheet Transition of Myoglobin

Hirai, M.; Ajito, S.; Sugiyama, M.; Iwase, H.; Takata, S.-i.; Shimizu, N.; Igarashi, N.; Martel, A.; Porcar, L.

10.1101/275321 — biophysics — Posted on 2018-03-08

1587 Weakly-bound Dimers that Underlie the Crystal Nucleation Precursors in Lysozyme Solutions

Vekilov, P. G.; McCabe, J. W.; Angel, L. A.; Hawke, D. H.; Byington, M. C.; Safari, M. S.; Lubchenko, V.; Conrad, J. C.

10.1101/275222 — biophysics — Posted on 2018-03-08

1588 Electromechanics and Volume Dynamics in Non-excitable Tissue Cells

Yellin, F.; Li, Y.; Sreenivasan, V. K. A.; Farrell, B.; Johny, M.; Yu, D.; Sun, S. X.

10.1101/275339 — biophysics — Posted on 2018-03-08

1589 A fluorescence correlation spectrometer for measurements in cuvettes

Sahoo, B.; Sil, T. B.; Karmakar, B.; Garai, K.

10.1101/275230 — biophysics — Posted on 2018-03-08

1590 Fast Parallel Algorithm for Large Fractal Kinetic Models with Diffusion

Shestov, A. A.; Popov, A. A.; Lee, S.-C.; Kuksa, P. P.; Glickson, J. D.

10.1101/275248 — biophysics — Posted on 2018-03-08

1591 Mathematical modeling and simulations for large-strain J-shaped diagrams of soft biological tissues

Koibuchi, H.; Mitsuhashi, K.; Ghosh, S.

10.1101/275206 — biophysics — Posted on 2018-03-08

1592 Comparison between O and OH intermediates of cytochrome c oxidase studied by FTIR spectroscopy.

Gorbikova, E.; Kalendar, R.

10.1101/275099 — biophysics — Posted on 2018-03-08

1593 Expansion stimulated emission depletion microscopy (ExSTED)

Gao, M.; Maraspini, R.; Beutel, O.; Zehtabian, A.; Eickholt, B.; Honigmann, A.; Ewers, H.

10.1101/278937 — biophysics — Posted on 2018-03-08

1594 Cellular structure analysis based on magnetic induction FEM simulations and measurements

tang, j.

10.1101/275271 — biophysics — Posted on 2018-03-08

1595 Altered Reward Processing in Abstinent Dependent Cannabis Users: Social Context Matters

Zimmermann, K.; Kendrick, K.; Scheele, D.; Dau, W.; Banger, M.; Maier, W.; Weber, B.; Ma, Y.; Hurlemann, R.; Becker, B.

10.1101/278044 — neuroscience — Posted on 2018-03-08

1596 Flexible Learning-Free Segmentation and Reconstruction for Sparse Neuronal Circuit Tracing

Shahbazi, A.; Kinnison, J.; Vescovi, R.; Du, M.; Hill, R.; Jösch, M.; Takeno, M.; Zeng, H.; da Costa, N. M.; Grutzendler, J.; Kasthuri, N.; Scheirer, W. J.

10.1101/278515 — neuroscience — Posted on 2018-03-08

1597 A network for computing value homeostasis in the human medial prefrontal cortex

Juechems, K.; Balaguer, J.; Herce Castanon, S.; Ruz, M.; O'Reilly, J. X.; Summerfield, C.

10.1101/278531 — neuroscience — Posted on 2018-03-08

1598 Physiology and lipid accumulation capacity of different Yarrowia lipolytica and Rhodosporidium toruloides strains on glycerol

Azambuja, S. P.; Bonturi, N.; Miranda, E. A.; Gombert, A. K.

10.1101/278523 — microbiology — Posted on 2018-03-08

1599 Ancient Genomics Reveals Four Prehistoric Migration Waves into Southeast Asia

McColl, H.; Racimo, F.; Vinner, L.; Demeter, F.; Wilken, U. G.; Moreno Mayar, J. V.; Seguin-Orlando, A.; de la Fuente Castro, C.; Wasef, S.; Prohaska, A.; Margarayan, A.; de Barros Damgaard, P.; Shoocongdej, R.; Souksavatdy, V.; Sayavongkhamdy, T.; Mokhtar Saidin, M.; Kaewsutthi, S.; Lertrit, P.; Nguyen, H. M.; Hung, H.-c.; Minh Tran, T.; Nghia Truong, H.; Shahidan, S.; Wiradnyana, K.; Bacon, A.-M.; Duringer, P.; Ponche, J.-L.; Shackelford, L.; Patole-Edoumba, E.; Tuan Nguyen, A.; Bellina-Pryce, B.; Galipaud, J.-C.; Kinaston, R.; Buckley, H.; Pottier, C.; Rasmussen, S.; Higham, T.; Foley, R. A

10.1101/278374 — evolutionary biology — Posted on 2018-03-08

1600 Developmental origin and morphogenesis of the diaphragm, an essential mammalian muscle

Sefton, E. M.; Gallardo, M.; Kardon, G.

10.1101/278507 — developmental biology — Posted on 2018-03-08

1601 The neuronal ceroid lipofuscinosis protein, Cln7, regulates neural development from the post-synaptic cell.

O'Hare, M. B.; Mohammed, A.; Connolly, K. J.; Aitchison, K. C.; Anthoney, N. C.; Roberts, A. L.; Taylor, M. J.; Stewart, B. A.; Tuxworth, R. I.; Tear, G.

10.1101/278895 — developmental biology — Posted on 2018-03-08

1602 Analyzing ecological networks of species interactions

Delmas, E.; Besson, M.; Brice, M.-H.; Burkle, L.; Dalla Riva, G. V.; Fortin, M.-J.; Gravel, D.; Guimaraes, P.; Hembry, D.; Newman, E.; Olesen, J. M.; Pires, M.; Yeakel, J. D.; Poisot, T.

10.1101/112540 — ecology — Posted on 2018-03-08

1603 OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer

Yepez, V. A.; Kremer, L. S.; Iuso, A.; Gusic, M.; Kopajtich, R.; Konarikova, E.; Nadel, A.; Wachutka, L.; Prokisch, H.; Gagneur, J.

10.1101/231522 — bioinformatics — Posted on 2018-03-08

1604 A phylogenomic framework and timescale for comparative studies of tunicates

Delsuc, F.; Philippe, H.; Tsagkogeorga, G.; Simion, P.; Tilak, M.-K.; Turon, X.; Lopez-Legentil, S.; Piette, J.; Lemaire, P.; Douzery, E. J. P.

10.1101/236448 — evolutionary biology — Posted on 2018-03-08

1605 The TRPC6-AMPK pathway is involved in cytoskeleton reorganization and glucose uptake in podocytes.

Rachubik, P.; Szrejder, M.; Rogacka, D.; Audzeyenka, I.; Rychłowski, M.; Angielski, S.; Piwkowska, A.

10.1101/278911 — cell biology — Posted on 2018-03-08

1606 Complementary studies of lipid membrane dynamics using iSCAT and STED Fluorescence Correlation Spectroscopy

Reina, F.; Galiani, S.; Shrestha, D.; Sezgin, E.; de Wit, G.; Cole, D.; Lagerholm, B. C.; Kukura, P.; Eggeling, C.

10.1101/235564 — biophysics — Posted on 2018-03-08

1607 Comparative Genomics of Staphylococcus Reveals Determinants of Speciation and Diversification of Antimicrobial Defense.

Coates-Brown, R.; Moran, J.; Pongchaikul, P.; Darby, A.; Horsburgh, M. J.

10.1101/277400 — microbiology — Posted on 2018-03-08

1608 Reproducible, flexible and high throughput data extraction from primary literature: The metaDigitise R package

Pick, J. L.; Nakagawa, S.; Noble, D. W.

10.1101/247775 — evolutionary biology — Posted on 2018-03-08

1609 Visualizing BDNF cell-to-cell transfer reveals astrocytes are the primary recipient of neuronal BDNF

Stahlberg, M. A.; Kuegler, S.; Dean, C.

10.1101/255935 — neuroscience — Posted on 2018-03-08

1610 Spatio-Temporal Gene Discovery For Autism Spectrum Disorder

Norman, U.; Cicek, A. E.

10.1101/256693 — bioinformatics — Posted on 2018-03-08

1611 Two novel strains of Torulaspora delbrueckii isolated from the honey bee microbiome and their use in honey fermentation

Barry, J. P.; Metz, M. S.; Hughey, J.; Quirk, A.; Bochman, M.

10.1101/264317 — microbiology — Posted on 2018-03-08

1612 Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,958)

Sanchez-Roige, S.; Palmer, A. A.; Fontanillas, P.; Elson, S.; 23andMe Research Team, ; Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, ; Adams, M. J.; Howard, D. M.; Edenberg, H. J.; Davies, G.; Crist, R. C.; Deary, I.; McIntosh, A. M.; Clarke, T. K.

10.1101/275917 — genetics — Posted on 2018-03-08

1613 Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

Ehlen, A.; Martin, C.; Julien, M.; Miron, S.; Theillet, F. X.; Boucherit, V.; Duchambon, P.; El Marjou, A.; Zinn Justin, S.; Carreira, A.

10.1101/265934 — cell biology — Posted on 2018-03-08

1614 Conserved Methyltransferase Spb1 Targets mRNAs for Regulated Modification with 2′-O-Methyl Ribose

Bartoli, K. M.; Schaening, C.; Carlile, T.; Gilbert, W. V.

10.1101/271916 — molecular biology — Posted on 2018-03-08

1615 Limit distribution of the quartet balance index for Aldous’s β ≥ 0–model

Bartoszek, K.

10.1101/277376 — evolutionary biology — Posted on 2018-03-08

1616 RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs

McClintock, M. A.; Dix, C. I.; Johnson, C. M.; McLaughlin, S. H.; Maizels, R. J.; Hoang, H. T.; Bullock, S. L.

10.1101/273912 — cell biology — Posted on 2018-03-08

1617 Novel approach to quantitative spatial gene expression uncovers genetic stochasticity in the developing Drosophila eye

Ali, S.; Signor, S.; Kozlov, K.; Nuzhdin, S.

10.1101/175711 — developmental biology — Posted on 2018-03-08

1618 GenomeDISCO: A concordance score for chromosome conformation capture experiments using random walks on contact map graphs

Ursu, O.; Boley, N.; Taranova, M.; Wang, Y. X. R.; Yardimci, G. G.; Noble, W. S.; Kundaje, A.

10.1101/181842 — bioinformatics — Posted on 2018-03-08

1619 Crossmodal congruency effect scores decrease with repeat test exposure

Gill, S.; Blustein, D.; Wilson, A.; Sensinger, J.

10.1101/186825 — neuroscience — Posted on 2018-03-08

1620 An expression atlas of chemosensory ionotropic glutamate receptors identifies a molecular basis of carbonation detection

Sanchez-Alcaniz, J. A.; Silbering, A. F.; Croset, V.; Zappia, G.; Sivasubramaniam, A. K.; Abuin, L.; Sahai, S. Y.; Auer, T. O.; Cruchet, S.; Neagu-Maier, G. L.; Sprecher, S. G.; Yapici, N.; Benton, R.

10.1101/278804 — neuroscience — Posted on 2018-03-08

1621 Alzheimer’s disease: the large gene instability hypothesis

Soheili-nezhad, S.; Zarei, M.

10.1101/189712 — neuroscience — Posted on 2018-03-08

1622 Membrane proteins with high N-glycosylation, high expression, and multiple interaction partners were preferred by mammalian viruses as receptors

Zhang, Z.; Zhu, Z.; Chen, W.; Cai, Z.; Xu, B.; Tan, Z.; Wu, A.; Ge, X.; Guo, X.; Tan, Z.; Xia, Z.; Zhu, H.; Jiang, T.; Peng, Y.

10.1101/271171 — microbiology — Posted on 2018-03-08

1623 The role of stochastic sequestration dynamics for intrinsic noise filtering in signaling network motifs

Paul, D.; Radde, N.

10.1101/278929 — systems biology — Posted on 2018-03-08

1624 Can Actin Depolymerization Actually Result In Increased Plant Resistance To Pathogens?

Krutinova, H.; Trda, L.; Kalachova, T.; Lamparova, L.; Pospichalova, R.; Dobrev, P.; Malinska, K.; Burketova, L.; Valentova, O.; Janda, M.

10.1101/278986 — plant biology — Posted on 2018-03-08

1625 Dimensionality Reduction on Spatio-Temporal Maximum Entropy Models of Spiking Networks

Herzog, R.; Escobar, M.-J.; Cofre, R.; Palacios, A. G.; Cessac, B.

10.1101/278606 — neuroscience — Posted on 2018-03-08

1626 Integration and segregation in Autism Spectrum Disorders modulated by age, disease, and interaction: A graph-theoretic study of intrinsic functional connectivity

Harlalka, V.; Naik, S.; Bapi, R. S.; Vinod, P. K.; Roy, D.

10.1101/278846 — neuroscience — Posted on 2018-03-08

1627 A systematic study of repetitive transcranial magnetic stimulation to enhance working memory manipulation abilities

Beynel, L.; Davis, S. W.; Crowell, C. A.; Hilbig, S. A.; Lim, W.; Nguyen, D.; Peterchev, A.; Luber, B.; Lisanby, S. H.; Cabeza, R.; Appelbaum, L. G.

10.1101/278655 — neuroscience — Posted on 2018-03-08

1628 The illusion of uniformity does not depend on low-level vision: evidence from sensory adaptation

Suarez-Pinilla, M.; Seth, A.; Roseboom, W.

10.1101/278721 — neuroscience — Posted on 2018-03-08

1629 Subject-specificity of the correlation between large-scale structural and functional connectivity

Zimmermann, J.; Griffiths, J.; Schirner, M.; Ritter, P.; McIntosh, R.

10.1101/277590 — neuroscience — Posted on 2018-03-08

1630 The expression tractability of a biological trait

Liu, L.; Wang, J.; Yang, J.; He, X.

10.1101/278770 — genomics — Posted on 2018-03-08

1631 DNA methylation age acceleration and risk factors for Alzheimer’s disease

McCartney, D. L.; Stevenson, A. J.; Walker, R. M.; Gibson, J.; Morris, S. W.; Campbell, A.; Murray, A. D.; Whalley, H. C.; Porteous, D. J.; McIntosh, A. M.; Evans, K. L.; Deary, I. J.; Marioni, R. E.

10.1101/278945 — genomics — Posted on 2018-03-08

1632 Finding Nemo’s Genes: A chromosome-scale reference assembly of the genome of the orange clownfish Amphiprion percula

Lehmann, R.; Lightfoot, D. J.; Schunter, C.; Michell, C. T.; Ohyanagi, H.; Mineta, K.; Foret, S.; Berumen, M.; Miller, D. J.; Aranda, M.; Gojobori, T.; Munday, P. L.; Ravasi, T.

10.1101/278267 — genomics — Posted on 2018-03-08

1633 Bees use anthropogenic habitats despite strong natural habitat preferences

Collado, M. A.; Sol, D.; Bartomeus, I.

10.1101/278812 — ecology — Posted on 2018-03-08

1634 Reverse-engineering flow-cytometry gating strategies for phenotypic labelling and high-performance cell sorting

Becht, E.; Simoni, Y.; Coustan-Smith, E.; Evrard, M.; Cheng, Y.; Ng, L. G.; Campana, D.; Newell, E.

10.1101/278796 — bioinformatics — Posted on 2018-03-08

1635 AIControl: Replacing matched control experiments with machine learning improves ChIP-seq peak identification

Hiranuma, N.; Lundberg, S. M.; Lee, S.-I.

10.1101/278762 — bioinformatics — Posted on 2018-03-08

1636 Loss of Peroxisomal Hydroxypyruvate Reductase Inhibits Triose Phosphate Isomerase but Stimulates Cyclic Photosynthetic Electron Flow and the Glc-6P-Phosphate Shunt

Li, J.; Weraduwage, S. M.; Preiser, A. L.; Weise, S. E.; Strand, D. D.; Froehlich, J. E.; Kramer, D. M.; Hu, J.; Sharkey, T. D.

10.1101/278580 — plant biology — Posted on 2018-03-08

1637 Slow peak alpha frequency and corticomotor depression linked to high pain susceptibility in transition to sustained pain

Seminowicz, D. A.; Thapa, T.; Furman, A. J.; Summers, S. J.; Cavaleri, R.; Fogarty, J. S.; Steiner, G. Z.; Schabrun, S. M.

10.1101/278598 — neuroscience — Posted on 2018-03-08

1638 Persistent Underrepresentation of Women’s Science in High Profile Journals

Shen, Y. A.; Webster, J. M.; Shoda, Y.; Fine, I.

10.1101/275362 — scientific communication and education — Posted on 2018-03-08

1639 Bub1 is not required for the checkpoint response to unattached kinetochores in diploid human cells

Currie, C. E.; Mora-Santos, M. D.; Smith, C.; McAinsh, A. D.; Millar, J. B.

10.1101/278820 — cell biology — Posted on 2018-03-08

1640 The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp

Duchi, D.; Mazumder, A.; Malinen, A. M.; Ebright, R.; Kapanidis, A.

10.1101/278838 — biophysics — Posted on 2018-03-08

1641 Three-dimensional cell geometry controls excitable membrane signaling in Dictyotelium cells

Hörning, M.; Shibata, T.

10.1101/278853 — biophysics — Posted on 2018-03-08

1642 Variational algorithms for analyzing noisy multi-state diffusion trajectories

Linden, M.; Elf, J.

10.1101/278978 — biophysics — Posted on 2018-03-08

1643 Decomposing the subclonal structure of tumors with two-way mixture models on copy number aberrations

Tai, A.-S.; Peng, C.-H.; Hsieh, W.-P.

10.1101/278887 — bioinformatics — Posted on 2018-03-08

1644 Study of the DiI method accuracy on the example of the afferent connections of the Habenula in P6 F1-C57Bl6 / CBA mice

Klepukov, A.; Apryshko, V.; Yakovenko, S.

10.1101/277541 — neuroscience — Posted on 2018-03-08

1645 Higher-Order Organization Principles of Pre-translational mRNPs

Metkar, M.; Ozadam, H.; Lajoie, B. R.; Imakaev, M.; Mirny, L. A.; Dekker, J.; Moore, M. J.

10.1101/278747 — molecular biology — Posted on 2018-03-08

1646 DeepProfile: Deep learning of patient molecular profiles for precision medicine in acute myeloid leukemia

Dincer, A. B.; Celik, S.; Hiranuma, N.; Lee, S.-I.

10.1101/278739 — bioinformatics — Posted on 2018-03-08

1647 Fasting protects hypoxia-induced defects in proteostasis in C. elegans

Iranon, N. N.; Jochim, B. E.; Miller, D. L.

10.1101/278671 — physiology — Posted on 2018-03-08

1648 Spatial and temporal PCP protein dynamics coordinate cell intercalation during neural tube closure

Butler, M.; Wallingford, J. B.

10.1101/278499 — developmental biology — Posted on 2018-03-08

1649 Epidermal YAP Activity Drives Canonical WNT16/β-catenin Signaling to Promote Keratinocyte Proliferation in vitro and in the Murine Skin

Mendoza-Reinoso, V.; Beverdam, A.

10.1101/278705 — developmental biology — Posted on 2018-03-08

1650 Non-Random Mis-Segregation of Human Chromosomes.

Worrall, J. T.; Tamura, N.; Shaikh, N.; Mazzagatti, A.; van Lingen, T.; Bakker, B.; Spierings, D. C. J.; Vladimirou, E.; Foijer, F.; McClelland, S. E.

10.1101/278697 — cell biology — Posted on 2018-03-08

1651 Cellular cooperation shapes tumor growth: a statistical mechanics mathematical model

West, J.; Newton, P. K.

10.1101/278614 — cancer biology — Posted on 2018-03-08

1652 Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters

Norris, S. R.; Jung, S.; Singh, P.; Strothman, C. E.; Erwin, A. L.; Ohi, M. D.; Zanic, M.; Ohi, R.

10.1101/278481 — biophysics — Posted on 2018-03-08

1653 Comprehensive catalog of dendritically localized mRNA isoforms from sub-cellular sequencing of single mouse neurons

Middleton, S. A.; Eberwine, J.; Kim, J.

10.1101/278648 — neuroscience — Posted on 2018-03-07

1654 Chromosome (mis)segregation is biased by kinetochore size

Drpic, D.; Almeida, A.; Aguiar, P.; Maiato, H.

10.1101/278572 — cell biology — Posted on 2018-03-07

1655 Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1

de Vera, I. M. S.; Munoz-Tello, P.; Dharmarajan, V.; Marciano, D. P.; Matta-Camacho, E.; Giri, P. K.; Shang, J.; Hughes, T. S.; Rance, M.; Griffin, P. R.; Kojetin, D. J.

10.1101/278440 — biophysics — Posted on 2018-03-07

1656 Robotic automation of droplet microfluidics

Tran, T. M.; Kim, S. C.; Abate, A. R.

10.1101/278556 — bioengineering — Posted on 2018-03-07

1657 Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high-fat-diet-induced insulin resistance

Chilloux, J.; Brial, F.; Everard, A.; Smyth, D.; Zhang, L.; Plovier, H.; Myridakis, A.; Hoyles, L.; Fuchs, J. E.; Blancher, C.; Gencer, S.; Martinez-Gili, L.; Fearnside, J. F.; Barton, R. H.; Neves, A. L.; Rothwell, A. R.; Gerard, C.; Calderari, S.; Boulange, C. L.; Patel, S.; Scott, J.; Glen, R. C.; Gooderham, N. J.; Nicholson, J. K.; Gauguier, D.; Liu, P. P.; Cani, P. D.; Dumas, M.-E. E.

10.1101/277434 — systems biology — Posted on 2018-03-07

1658 Gene regulatory network analysis identifies sex-linked differences in colon cancer drug metabolism processes

Lopes-Ramos, C. M.; Kuijjer, M. L.; Ogino, S.; Fuchs, C. S.; DeMeo, D. L.; Glass, K.; Quackenbush, J.

10.1101/277186 — systems biology — Posted on 2018-03-07

1659 Inferring causal pathways among three or more variables from steady-state correlations in a homeostatic system

Chawla, S.; Pund, A.; B, V.; Kulkarni, S.; Diwekar, M.; Watve, M.

10.1101/278101 — physiology — Posted on 2018-03-07

1660 An afferent subcortical white matter pathway to the amygdala facilitates fear recognition

McFadyen, J.; Mattingley, J. B.; Garrido, M. I.

10.1101/277368 — neuroscience — Posted on 2018-03-07

1661 Layer 3 dynamically coordinates columnar activity during spatial integration in mouse V1

Plomp, G.; Larderet, I.; Fiorini, M.; Busse, L.

10.1101/277533 — neuroscience — Posted on 2018-03-07

1662 Improving night-time sleep with hypnotic suggestions

Cordi, M.; Rossier, L.; Rasch, B.

10.1101/277566 — neuroscience — Posted on 2018-03-07

1663 Avoiding sedentary behaviors requires more cortical resources than avoiding physical activity: An EEG study

Cheval, B.; Tipura, E.; Burra, N.; Frossard, J.; Chanal, J.; Orsholits, D.; Radel, R.; Boisgontier, M. P.

10.1101/277988 — neuroscience — Posted on 2018-03-07

1664 Integrin beta1 optimizes diabetogenic T cell migration and function in the pancreas

Espinosa-Carrasco, G.; Le Saout, C.; Fontanaud, P.; Michau, A.; Mollard, P.; Hernandez, J.; Schaeffer, M.

10.1101/277418 — immunology — Posted on 2018-03-07

1665 Genome-wide Methylation Patterns Under Caloric Restriction in Daphnia magna.

Hearn, J.; Pearson, M.; Blaxter, M.; Wilson, P. J.; Little, T. J.

10.1101/278408 — genomics — Posted on 2018-03-07

1666 Why Should Mitochondria Define Species?

Stoeckle, M. Y.; Thaler, D. S.

10.1101/276717 — evolutionary biology — Posted on 2018-03-07

1667 Limit distribution of the quartet balance index for Aldous’s β ≥ 0–model

Bartoszek, K.

10.1101/277376 — evolutionary biology — Posted on 2018-03-07

1668 Microhabitat Heterogeneity Promotes Partition of Resources by Syntopic Peromyscus in a Midlatitude Temperate Forest

De la Cruz-Arguello, I. M.; Castro-Campillo, A.; Zavala-Hurtado, A.; Salame-Mendez, A.; Ramirez-Pulido, J.

10.1101/278390 — ecology — Posted on 2018-03-07

1669 Intracellular FMRpolyG-HSP70 complex: Possible use as biochemical marker of Fragile X Tremor Ataxia Syndrome

Bonapace, G.; Gullace, R.; Concolino, D.; Iannello, G.; Procopio, R.; Gagliardi, M.; Arabia, G.; Barbagallo, G.; Lupo, A.; Manfredini, L. I.; Annesi, G.; Quattrone, A.

10.1101/278416 — cell biology — Posted on 2018-03-07

1670 pathfindR: An R Package for Pathway Enrichment Analysis Utilizing Active Subnetworks

Ulgen, E.; Ozisik, O.; Sezerman, O. U.

10.1101/272450 — bioinformatics — Posted on 2018-03-07

1671 Inhibition of acetyl-CoA carboxylase by spirotetramat causes lipid depletion and surface coat deficiency in nematodes

Gutbrod, P.; Gutbrod, K.; Nauen, R.; Elashry, A.; Siddique, S.; Benting, J.; Doermann, P.; Grundler, F. M. W.

10.1101/278093 — biochemistry — Posted on 2018-03-07

1672 Time Dependent Stochastic mRNA and Protein Synthesis in Piecewise-deterministic Models of Gene Networks.

Innocentini, G.; Hodgkinson, A.; Radulescu, O.

10.1101/278226 — systems biology — Posted on 2018-03-07

1673 Kynurenine 3-monooxygenase (KMO) is a critical regulator of renal ischemia-reperfusion injury

Zheng, X.; Zhang, A.; Binnie, M.; McGuire, K.; Webster, S. P.; Hughes, J.; Howie, S.; Mole, D.

10.1101/272765 — pathology — Posted on 2018-03-07

1674 Effects of transcranial focused ultrasound on human primary motor cortex using 7T fMRI

Ai, L.; Bansal, P.; Mueller, J. K.; Legon, W.

10.1101/277608 — neuroscience — Posted on 2018-03-07

1675 Genetic and environmental influence on the human functional connectome

Reineberg, A. E.; Hatoum, A. S.; Hewitt, J. K.; Banich, M. T.; Friedman, N. P.

10.1101/277996 — neuroscience — Posted on 2018-03-07

1676 Binaural fusion involves weak interaural suppression

Baker, D.; Vilidaite, G.; McClarnon, E.; Valkova, E.; Millman, R.

10.1101/278192 — neuroscience — Posted on 2018-03-07

1677 A Deep Predictive Coding Network for Learning Latent Representations

Dora, S.; Pennartz, C. M. A.; Bohte, S. M.

10.1101/278218 — neuroscience — Posted on 2018-03-07

1678 Subject-specificity of the correlation between large-scale structural and functional connectivity

Zimmermann, J.; Griffiths, J.; Schirner, M.; Ritter, P.; McIntosh, R.

10.1101/277590 — neuroscience — Posted on 2018-03-07

1679 Shared contextual knowledge strengthens inter-subject synchrony and pattern similarity in the semantic network

Raykov, P. P.; Keidel, J. L.; Oakhill, J.; Bird, C. M.

10.1101/276683 — neuroscience — Posted on 2018-03-07

1680 Distinct value encoding in striatal direct and indirect pathways during adaptive learning

Donahue, C. H.; Liu, M.; Kreitzer, A.

10.1101/277855 — neuroscience — Posted on 2018-03-07

1681 Formation of tRNA wobble inosine in humans is perturbed by a millennia-old mutation linked to intellectual disability

Ramos, J.; Han, L.; Li, Y.; Alkuraya, F. S.; Phizicky, E. M.; Fu, D.

10.1101/277079 — molecular biology — Posted on 2018-03-07

1682 The human leukemia virus HTLV-1 alters the structure and transcription of host chromatin in cis

Melamed, A.; Yaguchi, H.; Miura, M.; Witkover, A.; Fitzgerald, T. W.; Birney, E.; Bangham, C. R. M.

10.1101/277335 — microbiology — Posted on 2018-03-07

1683 Comprehensive analysis of small RNA profile by massive parallel sequencing in HTLV-1 asymptomatic subjects with monoclonal and polyclonal rearrangement of the T-cell antigen receptor γ-chain

Valadao de Souza, D. R.; Pessoa, R.; Nukui, Y.; Pereira, J.; Casseb, J.; Penalva de Oliveira, A. C.; Clissa, P. B.; Sanabani, S. S.

10.1101/277871 — microbiology — Posted on 2018-03-07

1684 The effect of strain level diversity on robust inference of virus-induced mortality

Beckett, S. J.; Weitz, J. S.

10.1101/277517 — microbiology — Posted on 2018-03-07

1685 American Gut: an Open Platform for Citizen-Science Microbiome Research

McDonald, D.; Hyde, E. R.; Debelius, J. W.; Morton, J. T.; Gonzalez, A.; Ackermann, G.; Aksenov, A. A.; Behsaz, B.; Brennan, C.; Chen, Y.; DeRight Goldasicha, L.; Dorrestein, P. C.; Dunn, R. R.; Fahimipourg, A. K.; Gaffney, J.; Gilbert, J. A.; Gogul, G.; Green, J. L.; Hugenholtz, P.; Humphrey, G.; Huttenhower, C.; Jackson, M. A.; Janssen, S.; Jeste, D. V.; Jiang, L.; Kelley, S. T.; Knights, D.; Kosciolek, T.; Ladau, J.; Leach, J.; Marotz, C.; Meleshko, D.; Melnik, A. V.; Metcalf, J. L.; Mohimani, H.; Montassier, E.; Navas-Molina, J.; Nguyen, T. T.; Peddada, S.; Pevzner, P.; Pollard, K. S.; Rah

10.1101/277970 — microbiology — Posted on 2018-03-07

1686 EukRef: phylogenetic curation of ribosomal RNA to enhance understanding of eukaryotic diversity and distribution

del Campo, J.; Kolisko, M.; Boscaro, V.; Santoferrara, L. F.; Massana, R.; Guillou, L.; Simpson, A.; Berney, C.; de Vargas, C.; Brown, M.; Keeling, P.; Wegener Parfrey, L.

10.1101/278085 — microbiology — Posted on 2018-03-07

1687 Comparative Genomics of Staphylococcus Reveals Determinants of Speciation and Diversification of Antimicrobial Defense.

Horsburgh, M. J.; Coates-Brown, R.; Darby, A.; Pongchaikul, P.; Moran, J.

10.1101/277400 — microbiology — Posted on 2018-03-07

1688 Genome-wide measurement of local nucleosome array regularity and spacing by nanopore sequencing

Baldi, S.; Krebs, S.; Blum, H.; Becker, P. B.

10.1101/272526 — genomics — Posted on 2018-03-07

1689 Constructing and visualizing cancer genomic maps in 3D spatial context by phenotype-based high-throughput laser-aided isolation and sequencing (PHLI-seq)

Kim, S.; Lee, A. C.; Lee, H.-B.; Kim, J.; Jung, Y.; Ryu, H. S.; Lee, Y.; Bae, S.; Lee, M.; Lee, K.; Kim, R. N.; Park, W.-Y.; Han, W.; Kwon, S.

10.1101/278010 — genomics — Posted on 2018-03-07

1690 Finding Nemo’s Genes: A chromosome-scale reference assembly of the genome of the orange clownfish Amphiprion percula

Lehmann, R.; Lightfoot, D. J.; Schunter, C.; Michell, C. T.; Ohyanagi, H.; Mineta, K.; Foret, S.; Berumen, M.; Miller, D. J.; Aranda, M.; Gojobori, T.; Munday, P. L.; Ravasi, T.

10.1101/278267 — genomics — Posted on 2018-03-07

1691 Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Qi, T.; Wu, Y.; Zeng, J.; Zhang, F.; Xue, A.; Jiang, L.; Zhu, Z.; Kemper, K.; Yengo, L.; Zheng, Z.; Consortium, e.; Marioni, R. E.; Montgomery, G. W.; Deary, I. J.; Wray, N. R.; Visscher, P. M.; McRae, A. F.; Yang, J.

10.1101/274472 — genetics — Posted on 2018-03-07

1692 High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability

Palamara, P. F.; Terhorst, J.; Song, Y. S.; Price, A. L.

10.1101/276931 — genetics — Posted on 2018-03-07

1693 Karyotype-environment associations support a role for a chromosomal inversion in local adaptation among North American populations of the seaweed fly Coelopa frigida

Merot, C.; Berdan, E.; Babin, C.; Normandeau, E.; Wellenreuther, M.; Bernatchez, L.

10.1101/278317 — evolutionary biology — Posted on 2018-03-07

1694 Understanding biodiversity at the pondscape using environmental DNA: a focus on great crested newts

Harper, L. R.; Lawson Handley, L.; Hahn, C.; Boonham, N.; Rees, H. C.; Lewis, E.; Adams, I. P.; Brotherton, P.; Phillips, S.; Hänfling, B.

10.1101/278309 — ecology — Posted on 2018-03-07

1695 Trends in female lifespan in South Korea, 1987-2016

Weon, B. M.

10.1101/278291 — ecology — Posted on 2018-03-07

1696 Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

Yoo, T. Y.; Choi, J.-M.; Yu, C.-H.; Pappu, R. V.; Needleman, D. J.

10.1101/276212 — cell biology — Posted on 2018-03-07

1697 Phosphorylation By CK2 Regulates MUS81/EME1 In Mitosis And After Replication Stress

Palma, A.; Pugliese, G. M.; Murfuni, I.; Marabitti, V.; Malacaria, E.; Rinalducci, S.; Minoprio, A.; Sanchez, M.; Mazzei, F.; Zolla, L.; Franchitto, A.; Pichierri, P.

10.1101/278143 — cell biology — Posted on 2018-03-07

1698 Tumor cell-adipocyte gap junctions activate lipolysis and are essential for breast tumorigenesis

Camarda, R.; Williams, J.; Malkov, S.; Zimmerman, L. J.; Manning, S.; Aran, D.; Beardsley, A.; Van de Mark, D.; Chen, Y.; Berdan, C. A.; Louie, S. M.; Mahieu, C.; Winkler, J.; Willey, E.; Gagnon, J. D.; Shinoda, K.; Ansel, K. M.; Werb, Z.; Nomura, D. K.; Kajimura, S.; Butte, A. J.; Sanders, M. E.; Liebler, D. C.; Rugo, H.; Krings, G.; Shepherd, J. A.; Goga, A.

10.1101/277939 — cancer biology — Posted on 2018-03-07

1699 Study on tumor cell RNA cross-anticancer mechanism in non-tumor mice experimental model

Xu, Q.

10.1101/277228 — cancer biology — Posted on 2018-03-07

1700 LED-based interference-reflection microscopy combined with optical tweezers for quantitative three-dimensional single microtubule imaging

Simmert, S.; Abdosamadi, M. K.; Hermsdorf, G.; Schäffer, E.

10.1101/277632 — biophysics — Posted on 2018-03-07

1701 Effect of Ca2+ on the promiscuous target-protein binding mechanism of calmodulin

Delemotte, L.; Westerlund, A.

10.1101/277327 — biophysics — Posted on 2018-03-07

1702 Tuning molecular motor transport through cytoskeletal filament network organization

Scholz, M.; Weirich, K. L.; Gardel, M. L.; Dinner, A. R.

10.1101/277947 — biophysics — Posted on 2018-03-07

1703 Single-molecular and Ensemble-level Oscillations of Cyanobacterial Circadian Clock

Das, S.; Terada, T. P.; Sasai, M.

10.1101/278184 — biophysics — Posted on 2018-03-07

1704 VIGA: a sensitive, precise and automatic de novo VIral Genome Annotator.

Gonzalez-Tortuero, E.; Sutton, T. D.; Velayudhan, V.; Shkoporov, A. N.; Draper, L. A.; Stockdale, S. R.; Ross, R. P.; Hill, C.

10.1101/277509 — bioinformatics — Posted on 2018-03-07

1705 VarQ: a tool for the structural analysis of Human Protein Variants

Radusky, L.; Modenutti, C. P.; Delgado, J.; Bustamante, J. P.; Vishnopolska, S.; Kiel, C.; Serrano, L.; Marti, M.; Turjanski, A. G.

10.1101/277491 — bioinformatics — Posted on 2018-03-07

1706 Comprehensive peptide quantification for data independent acquisition mass spectrometry using chromatogram libraries

Searle, B. C.; Pino, L. K.; Egertson, J. D.; Ting, Y. S.; Lawrence, R. T.; Villen, J.; MacCoss, M. J.

10.1101/277822 — biochemistry — Posted on 2018-03-07

1707 Primary Motor Cortex Encodes A Temporal Difference Reinforcement Learning Process

Tarigoppula, V. S. A.; Choi, J. S.; Hessburg, J. H.; McNiel, D. B.; Marsh, B. T.; Francis, J. T.

10.1101/257337 — neuroscience — Posted on 2018-03-07

1708 Generation and validation of homozygous fluorescent knock-in cells using genome editing

Koch, B.; Nijmeijer, B.; Kueblbeck, M.; Cai, Y.; Walther, N.; Ellenberg, J.

10.1101/188847 — molecular biology — Posted on 2018-03-07

1709 Deciphering cis-regulatory logic with 100 million random promoters

de Boer, C.; Sadeh, R.; Friedman, N.; Regev, A.

10.1101/224907 — genomics — Posted on 2018-03-07

1710 mRNA structure determines specificity of a polyQ-driven phase separation

Langdon, E. M.; Qiu, Y.; Ghanbari Niaki, A.; McLaughlin, G.; Weidmann, C.; Gerbich, T.; Smith, J. A.; Crutchley, J. M.; Termini, C. M.; Weeks, K. M.; Myong, S.; Gladfelter, A.

10.1101/233817 — cell biology — Posted on 2018-03-07

1711 Dynamical model of the CLC-2 ion channel exhibits a two-step gating mechanism

McKiernan, K. A.; Koster, A. K.; Maduke, M.; Pande, V. S.

10.1101/228163 — biophysics — Posted on 2018-03-07

1712 A Data Citation Roadmap for Scientific Publishers

Cousijn, H.; Kenall, A.; Ganley, E.; Harrison, M.; Kernohan, D.; Lemberger, T.; Murphy, F.; Polischuk, P.; Taylor, S.; Martone, M.; Clark, T.

10.1101/100784 — scientific communication and education — Posted on 2018-03-07

1713 Impeding DNA Break Repair Enables Oocyte Quality Control

Qiao, H.; Rao, H. B. D. P.; Yun, Y.; Sandhu, S.; Fong, J. H.; Sapre, M.; Nguyen, M.; Tham, A.; Van, B. W.; Chng, T. Y. H.; Lee, A.; Hunter, N.

10.1101/277913 — genetics — Posted on 2018-03-07

1714 Effects Of Δ9-THC And Cannabidiol Vapor Inhalation In Male And Female Rats

Javadi-Paydar, M.; Nguyen, J. D.; Kerr, T. M.; Grant, Y.; Vandewater, S. A.; Cole, M.; Taffe, M. A.

10.1101/128173 — pharmacology and toxicology — Posted on 2018-03-07

1715 Why not record from every channel with a CMOS scanning probe?

Dimitriadis, G.; Neto, J. P.; Aarts, A.; Alexandru, A.; Ballini, M.; Battaglia, F.; Calcaterra, L.; David, F.; Fiath, R.; Frazao, J.; Geerts, J. P.; Gentet, L. J.; Helleputte, N. V.; Holzhammer, T.; Hoof, C. v.; Horvath, D.; Lopes, G.; Lopez, C. M.; Maris, E.; Marques-Smith, A.; Marton, G.; Meszena, D.; Mitra, S.; Musa, S.; Neves, H.; Nogueira, J.; Orban, G. A.; Pothof, F.; Putzeys, J.; Raducanu, B.; Ruther, P.; Schroeder, T.; Singer, W.; Tiesinga, P.; Ulbert, I.; Wang, S.; Welkenhuysen, M.; Kampff, A. R.

10.1101/275818 — neuroscience — Posted on 2018-03-07

1716 The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

Rajkumar, A. P.; Qvist, P.; Larsen, S. H.; Lazarus, R.; Pallesen, J.; Nava, N.; Winther, G.; Liebenberg, N.; Paternoster, V.; Fryland, T.; Palmfeldt, J.; Fejgin, K.; Mork, A.; Nyegaard, M.; Pakkenberg, B.; Didriksen, M.; Nyengaard, J. R.; Wegener, G.; Mors, O.; Christensen, J. H.; Borglum, A. D.

10.1101/257170 — neuroscience — Posted on 2018-03-07

1717 Spatial correlation as an early warning signal of regime shifts in a multiplex disease-behaviour network

Jentsch, P. C.; Anand, M.; Bauch, C. T.

10.1101/195388 — epidemiology — Posted on 2018-03-07

1718 RECTA: Regulon Identification Based on Comparative Genomics and Transcriptomics Analysis

Chen, X.; Ma, A.; McDermaid, A.; Zhang, H.; Liu, C.; Cao, H.; Ma, Q.

10.1101/261453 — systems biology — Posted on 2018-03-07

1719 The IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING 9 protein is a regulator of basal immunity in Arabidopsis thaliana

Wang, Y.; Rosas-Diaz, T.; Caceres-Moreno, C.; Lozano-Duran, R.; Macho, A.

10.1101/277269 — plant biology — Posted on 2018-03-07

1720 Ongoing, rational calibration of reward-driven perceptual biases

Fan, Y.; Gold, J. I.; Ding, L.

10.1101/242651 — neuroscience — Posted on 2018-03-07

1721 The ecological genetics of Pseudomonas syringae from kiwifruit leaves

Straub, C.; Colombi, E.; Li, L.; Huang, H.; Templeton, M. D.; McCann, H. C.; Rainey, P. B.

10.1101/235853 — microbiology — Posted on 2018-03-07

1722 CLASP promotes microtubule array reorientation by acting as a specific severing rescue factor

Lindeboom, J. J.; Nakamura, M.; Saltini, M.; Hibbel, A.; Walia, A.; Keetlaar, T.; Emons, A. M. C.; Sedbrook, J. C.; Kirik, V.; Mulder, B. M.; Ehrhardt, D. W.

10.1101/196329 — cell biology — Posted on 2018-03-07

1723 Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer

Vahrenkamp, J. M.; Yang, C.-H.; Rodriguez, A. C.; Almomen, A.; Berrett, K.; Trujillo, A. N.; Guillen, K. P.; Welm, B. E.; Jarboe, E. A.; Janat-Amsbury, M. M.; Gertz, J.

10.1101/199448 — cancer biology — Posted on 2018-03-07

1724 DeepQSM - Using Deep Learning to Solve the Dipole Inversion for MRI Susceptibility Mapping

Rasmussen, K. G. B.; Kristensen, M. J.; Blendal, R. G.; Ostergaard, L. R.; Plocharski, M.; O'Brien, K.; Langkammer, C.; Janke, A.; Barth, M.; Bollmann, S.

10.1101/278036 — neuroscience — Posted on 2018-03-07

1725 Dynamic virulence-related regions of the fungal plant pathogen Verticillium dahliae display remarkably enhanced sequence conservation

Depotter, J.; Shi-Kunne, X.; Missionnier, H.; Liu, T.; Faino, L.; van den Berg, G.; Wood, T.; Zhang, B.; Jacques, A.; Seidl, M.; Thomma, B.

10.1101/277558 — microbiology — Posted on 2018-03-07

1726 Foraging theory and the propensity to be obese: an alternative to thrift

Watve, M.; Baig, U.; Lokhande, L.; Lalwani, P.; Chawla, S.

10.1101/278077 — evolutionary biology — Posted on 2018-03-07

1727 Fusible alloy ‘in-contact’ microelectrodes: a rapid and economic microfabrication alternative for microfluidic impedance cytometry

Panwar, J.; Roy, R.

10.1101/278069 — bioengineering — Posted on 2018-03-07

1728 Spontaneous emergence of self-replication in chemical reaction systems

Liu, Y.; Sumpter, D. J. T.

10.1101/278119 — biochemistry — Posted on 2018-03-07

1729 A dual sRNA in Staphylococcus aureus induces a metabolic switch responding to glucose consumption

Bronesky, D.; Desgranges, E.; Corvaglia, A.; Francois, P.; Caballero, C. J.; Prado, L.; Toledo-Arana, A.; Lasa, I.; Moreau, K.; Vandenesch, F.; Marzi, S.; Romby, P.; Caldelari, I.

10.1101/278127 — microbiology — Posted on 2018-03-07

1730 Experimentally Induced Metamorphosis in Axolotl (Ambystoma mexicanum) Under Constant Diet Restructures Microbiota Accompanied by Reduced Limb Regenerative Capacity

Demircan, T.; Ovezmyradov, G.; YILDIRIM, B.; Keskin, I.; ilhan, A. E.; Fescioglu, E. C.; Ozturk, G.; Yildirim, S.

10.1101/277285 — microbiology — Posted on 2018-03-07

1731 The nidogen-domain containing protein DEX-1 is required for epidermal remodeling in C. elegans dauers

Flatt, K.; Beshers, C.; Unal, C.; Schroeder, N.

10.1101/277798 — genetics — Posted on 2018-03-07

1732 Adenylosuccinate Lyase activity in the Purine recycling pathway is essential for developmental timing, germline maintenance and muscle integrity in C. elegans.

Marsac, R.; Pinson, B.; Saint-Marc, C.; Olmedo, M.; Artal-Sanz, M.; Daignan-Fornier, B.; Gomes, J.-E.

10.1101/277640 — genetics — Posted on 2018-03-07

1733 Genetic basis of thermal plasticity variation in Drosophila melanogaster body size

Lafuente, E.; Duneau, D.; Beldade, P.

10.1101/268201 — evolutionary biology — Posted on 2018-03-07

1734 MetaWRAP - a flexible pipeline for genome-resolved metagenomic data analysis

Uritskiy, G. V.; DiRuggiero, J.; Taylor, J.

10.1101/277442 — microbiology — Posted on 2018-03-06

1735 Excitability regulation in the dorsomedial prefrontal cortex during sustained instructed fear responses: a TMS-EEG study

Gonzalez-Escamilla, G.; Chirumamilla, V. C.; Meyer, B.; Bonertz, T.; von Grothus, S.; Vogt, J.; Stroh, A.; Tuescher, O.; Kalisch, R.; Muthuraman, M.; Groppa, S.

10.1101/277806 — neuroscience — Posted on 2018-03-06

1736 Functional Asymmetries between Central and Peripheral Retinal Ganglion Cells in a Diurnal Rodent

Escobar, M.-J.; Otero, M.; Reyes, C.; Herzog, R.; Araya, J.; Ibaceta, C.; Palacios, A. G.

10.1101/277814 — neuroscience — Posted on 2018-03-06

1737 A reference haplotype panel for genome-wide imputation of short tandem repeats

Saini, S.; Mitra, I.; Gymrek, M.

10.1101/277673 — genomics — Posted on 2018-03-06

1738 Synaptonemal complex architecture facilitates the chromosome-specific regulation of recombination in Drosophila

Cahoon, C.; Heenan, G. M.; Yu, Z.; Unruh, J. R.; McKinney, S.; Hawley, R. S.

10.1101/277764 — genetics — Posted on 2018-03-06

1739 A novel GATA-binding protein 4 gene variation associated with familial atrial septal defect

Yang, Y.; Xia, Y.; Wu, Y.; Huang, S.; Teng, Y.; Liu, X.; Li, P.; Chen, J.; Zhuang, J.

10.1101/277780 — genetics — Posted on 2018-03-06

1740 ASD and ADHD have a similar burden of rare protein-truncating variants

Satterstrom, F. K.; Walters, R. K.; Singh, T.; Wigdor, E. M.; Lescai, F.; Demontis, D.; Kosmicki, J. A.; Grove, J.; Stevens, C.; Bybjerg-Grauholm, J.; Baekvad-Hansen, M.; Palmer, D. S.; Maller, J. B.; iPSYCH-Broad Consortium, ; Nordentoft, M.; Mors, O.; Robinson, E. B.; Hougaard, D. M.; Werge, T. M.; Bo Mortensen, P.; Neale, B. M.; Borglum, A. D.; Daly, M. J.

10.1101/277707 — genetics — Posted on 2018-03-06

1741 Analysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene induced by CRISPR-Cas9 RNPs

10.1101/277715 — genetics — Posted on 2018-03-06

1742 mTORC1 controls glycogen synthase kinase 3β nuclear localization and function

Bautista, S. J.; Boras, I.; Vissa, A.; Mecica, N.; Yip, C. M.; Kim, P. K.; Antonescu, C. N.

10.1101/277657 — cell biology — Posted on 2018-03-06

1743 Machine learning models to predict in vivo drug response via optimal dimensionality reduction of tumour molecular profiles

Nguyen, L.; Naulaerts, S.; Bomane, A.; Bruna, A.; Ghislat, G.; Ballester, P.

10.1101/277772 — bioinformatics — Posted on 2018-03-06

1744 ExTraMapper: Exon- and Transcript-level mappings for orthologous gene pairs

Ay, F.; Chakraborty, A.; Davuluri, R. V.

10.1101/277723 — bioinformatics — Posted on 2018-03-06

1745 We need to talk about reliability: Making better use of test retest studies for study design and interpretation

Matheson, G. J.

10.1101/274894 — neuroscience — Posted on 2018-03-06

1746 Distance-dependent changes in courtship song amplitude reflect song state changes

Suri, H.; Rajan, R.

10.1101/277210 — neuroscience — Posted on 2018-03-06

1747 Focal optogenetic suppression in macaque area MT biases direction discrimination and choice confidence, but only transiently

Fetsch, C. R.; Odean, N. N.; Jeurissen, D.; El-Shamayleh, Y.; Horwitz, G. D.; Shadlen, M. N.

10.1101/277251 — neuroscience — Posted on 2018-03-06

1748 The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

Choudhary, K. S.; Mih, N.; Monk, J.; Kavvas, E.; Yurkovich, J. T.; Sakoulas, G.; Palsson, B. O.

10.1101/277277 — microbiology — Posted on 2018-03-06

1749 Hospitalized premature infants are colonized by related bacterial strains with distinct proteomic profiles

Brown, C. T.; Xiong, W.; Olm, M. R.; Thomas, B. C.; Baker, R.; Firek, B.; Morowitz, M. J.; Hettich, R. L.; Banfield, J. F.

10.1101/217950 — microbiology — Posted on 2018-03-06

1750 Genome-wide analysis reveals distinct genetic mechanisms of diet-dependent lifespan and healthspan in D. melanogaster

Wilson, K. A.; Nelson, C. S.; Beck, J. N.; Brem, R. B.; Kapahi, P.

10.1101/153791 — genetics — Posted on 2018-03-06

1751 Reply: Neutral tumor evolution?

Heide, T.; Zapata, L.; Williams, M. J.; Werner, B.; Barnes, C. P.; Graham, T.; Sottoriva, A.

10.1101/274142 — cancer biology — Posted on 2018-03-06

1752 Model for breast cancer diversity and spatial heterogeneity

Romero-Arias, J. R.; Ramirez-Santiago, G.; Velasco-Hernandez, J.; Ohm, L.; Hernandez-Rosales, M.

10.1101/276725 — cancer biology — Posted on 2018-03-06

1753 Label-free high-speed wide-field imaging of single microtubules using interference reflection microscopy

Mahamdeh, M.; Simmert, S.; Luchniak, A.; Schaeffer, E.; Howard, J.

10.1101/273086 — biophysics — Posted on 2018-03-06

1754 Direct Measurement of Dissipation in a Single Protein using Small Amplitude Atomic Force Microscopy

Rajput, S. S.; Talele, S. V.; Ahlawat, V.; Ajith, V.; Roychoudhury, A.; Kamerkar, S.; Patil, S. V.

10.1101/275065 — biophysics — Posted on 2018-03-06

1755 Dual roles of electrostatic-steering and conformational dynamics in the binding of calcineurin’s intrinsically-disordered recognition domain to calmodulin

Sun, B.; Cook, E. C.; Creamer, T. P.; Kekenes-Huskey, P. M.

10.1101/277236 — biophysics — Posted on 2018-03-06

1756 Knomics-Biota - a system for exploratory analysis of human gut microbiota data

Popenko, A.; Tyakht, A.; Vasilyev, A.; Altukhov, I.; Efimova, D.; Odintsova, V.; Klimenko, N.; Loshkarev, R.; Pashkova, M.; Elizarova, A.; Voroshilova, V.; Slavskii, S.; Pekov, Y.; Filipova, E.; Shashkova, T.; Levin, E.; Alexeev, D.

10.1101/274993 — bioinformatics — Posted on 2018-03-06

1757 Three-dimensional plant architecture and sunlit-shaded patterns: a stochastic model of light dynamics in canopies

Retkute, R.; Townsend, A. J.; Murchie, E. H.; Jensen, O. E.; Preston, S. P.

10.1101/147553 — plant biology — Posted on 2018-03-06

1758 The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

10.1101/257170 — neuroscience — Posted on 2018-03-06

1759 MYC Dysregulates Mitotic Spindle Function Creating a Dependency on TPX2

Rohrberg, J.; Corella, A.; Taileb, M.; Kilinc, S.; Jokisch, M.-L.; Camarda, R.; Zhou, A.; Balakrishnan, S.; Chang, A. N.; Goga, A.

10.1101/272336 — cell biology — Posted on 2018-03-06

1760 Convolutional neural network, personalised, closed-loop Brain-Computer Interfaces for multi-way control mode switching in real-time

Ortega, P.; Colas, C.; Faisal, A.

10.1101/256701 — bioengineering — Posted on 2018-03-06

1761 Human Episodic Memory Retrieval Is Accompanied By A Neural Contiguity Effect

Folkerts, S.; Rutishauser, U.; Howard, M.

10.1101/117010 — neuroscience — Posted on 2018-03-06

1762 Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment: Insights from a hybrid multiscale cellular automaton model

Bowness, R.; Chaplain, M. A. J.; Powathill, G. G.; Gillespie, S. H.

10.1101/059113 — microbiology — Posted on 2018-03-06

1763 vqtl: An R package for Mean-Variance QTL Mapping

Corty, R. W.; Valdar, W.

10.1101/149377 — genetics — Posted on 2018-03-06

1764 Differential Proportionality - A Normalization-Free Approach To Differential Gene Expression

Erb, I.; Quinn, T.; Lovell, D.; Notredame, C.

10.1101/134536 — bioinformatics — Posted on 2018-03-06

1765 Critical comparison of ultracentrifugation and a commercial kit for isolation of exosomes derived from glioblastoma and breast cancer cell lines

Skottvoll, F. S.; Berg, H. E.; Bjorseth, K.; Lund, K.; Roos, N.; Bekhradnia, S.; Thiede, B.; Roberg-Larsen, H.; Nystrom, B.; Lundanes, E.; Wilson, S. R.

10.1101/274910 — biochemistry — Posted on 2018-03-06

1766 Removing neural correlations improves population sensitivity in MT/MST in response to random dot stimuli

Chaplin, T. A.; Hagan, M. A.; Allitt, B. J.; Rosa, M. G.; Lui, L. L.

10.1101/267732 — neuroscience — Posted on 2018-03-06

1767 Glyoxalase (GLO1) inhibition or genetic overexpression does not alter ethanol locomotor effects: implications for GLO1 as a therapeutic target in alcohol use disorders

Barkley-Levenson, A. M.; Lagarda, F. A.; Palmer, A. A.

10.1101/239624 — neuroscience — Posted on 2018-03-06

1768 Limitations of compensatory plasticity: the organization of the primary sensorimotor cortex in foot-using bilateral upper limb dysplasics

Striem-Amit, E.; Vannuscorps, G.; Caramazza, A.

10.1101/190462 — neuroscience — Posted on 2018-03-06

1769 Time without clocks: Human time perception based on perceptual classification

Roseboom, W.; Fountas, Z.; Nikiforou, K.; Bhowmik, D.; Shanahan, M.; Seth, A. K.

10.1101/172387 — neuroscience — Posted on 2018-03-06

1770 Schizophrenia Exhibits Bi-Directional Brain-Wide Alterations in Cortico-Striato-Cerebellar Circuits

Ji, J. L.; Diehl, C.; Schleifer, C.; Tamminga, C. A.; Keshavan, M.; Sweeney, J.; Clementz, B.; Hill, S. K.; Pearlson, G.; Yang, G.; Creatura, G.; Krystal, J.; Repovs, G.; Murray, J. D.; Winkler, A.; Anticevic, A.

10.1101/166728 — neuroscience — Posted on 2018-03-06

1771 A compartmentalized signaling network mediates crossover control in meiosis

Zhang, L.; Koehler, S.; Rillo-Bohn, R.; Dernburg, A. F.

10.1101/168948 — cell biology — Posted on 2018-03-06

1772 The IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING 9 protein is a regulator of basal immunity in Arabidopsis thaliana

Wang, Y.; Rosas-Diaz, T.; Caceres-Moreno, C.; Lozano-Duran, R.; Macho, A.

10.1101/277269 — plant biology — Posted on 2018-03-06

1773 Heparan sulfate molecules mediate synapse formation and function of male mating neural circuits in C. elegans

Lazaro-Pena, M. I.; Diaz-Balzac, C. A.; Buelow, H. E.; Emmons, S.

10.1101/277137 — neuroscience — Posted on 2018-03-06

1774 Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis

Iovanna, J. L.; Santofimia-Castano, P.; Lan, W.; Bintz, J.; Gayet, O.; Carrier, A.; Lomberk, G. A.; Neira, J. l.; Gonzalez, A.; Urrutia, R. A.; Soubeyran, P.

10.1101/277384 — cell biology — Posted on 2018-03-06

1775 Deficiency of the E3 Ubiquitin Ligase RBCK1 Causes Diffuse Brain Polyglucosan Accumulation and Neurodegeneration

Sullivan, M. A.; Nitschke, F.; Chown, E. E.; DiGiovanni, L. F.; Chown, M.; Perri, A. M.; Mitra, S.; Zhao, X.; Ackerley, C. A.; Israelian, L.; Ahonen, S.; Wang, P.; Minassian, B. A.

10.1101/277392 — molecular biology — Posted on 2018-03-06

1776 Towards Improving Embryo Selection: Simultaneous Next Generation Sequencing Of DNA And RNA From A Single Trophectoderm Biopsy

Fuchs Weizman, N.; Wyse, B.; Antes, R.; Ibarrientos, Z.; Sangaralingam, M.; Motamedi, G.; Kuznyetsov, V.; Madjunkova, S.; Librach, C. L.

10.1101/277103 — developmental biology — Posted on 2018-03-06

1777 Intermediate filaments EXC-2 and IFA-4 Maintain Luminal Structure of the Tubular Excretory Canals in Caenorhabditis elegans

Al-Hashimi, H. I.; Hall, D. H.; Ackley, B. D.; Lundquist, E. A.; Buechner, M.

10.1101/277111 — developmental biology — Posted on 2018-03-06

1778 Optogenetic reconstitution reveals that Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble

Okumura, M.; Natsume, T.; Kanemaki, M. T.; Kiyomitsu, T.

10.1101/277202 — cell biology — Posted on 2018-03-06

1779 Near-Infrared Spectroscopy for metabolite quantification and species identification

Aw, W. C.; Ballard, J. W. O.

10.1101/277053 — biochemistry — Posted on 2018-03-06

1780 A Russian validation study of the Coma Recovery Scale-Revised (CRS-R)

Mochalova, E.; Legostaeva, L.; Zimin, A.; Sergeev, D.; Domashenko, M.; Samorukov, V.; Yusupova, D.; Ryabinkina, J.; Suponeva, N.; Piradov, M.; Bodien, Y.; Giacino, J.

10.1101/276881 — neuroscience — Posted on 2018-03-06

1781 Comparison of different methods for average anatomical templates creation: do we really gain anything from a diffeomorphic framework?

Fonov, V.; Collins, D. L.

10.1101/277087 — neuroscience — Posted on 2018-03-06

1782 Assessment of cognitive reserve using near infrared spectroscopy

Medvedev, A.

10.1101/276865 — neuroscience — Posted on 2018-03-06

1783 Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,958)

10.1101/275917 — genetics — Posted on 2018-03-06

1784 Latent-Based Imputation of Laboratory Measures from Electronic Health Records: Case for Complex Diseases

Abedi, V.; Shivakumar, M. K.; Lu, P.; Hontecillas, R.; Leber, A.; Ahuja, M.; Ulloa, A. E.; Shellenberger, J. M.; Bassaganya-Riera, J.

10.1101/275743 — bioinformatics — Posted on 2018-03-06

1785 Endogenous protection from ischemic brain injury by preconditioned monocytes

Garcia-Bonilla, L.; Brea, D.; Benakis, C.; Lane, D.; Murphy, M.; Moore, J.; Racchumi, G.; Jiang, X.; Iadecola, C.; Anrather, J.

10.1101/276923 — neuroscience — Posted on 2018-03-06

1786 Inflammatory bowel disease microbiotas alter gut CD4 T-cell homeostasis and drive colitis in mice

Britton, G. J.; Contijoch, E. J.; Mogno, I.; Vennaro, O. H.; Llewellyn, S. R.; Ng, R.; Li, Z.; Mortha, A.; Merad, M.; Das, A.; Gevers, D.; McGovern, D. P.; Singh, N.; Braun, J.; Jacobs, J. P.; Clemente, J. C.; Grinspan, A.; Sands, B. E.; Colombel, J.-F.; Dubinsky, M. C.; Faith, J. J.

10.1101/276774 — immunology — Posted on 2018-03-06

1787 Adrenergic activation of cardiac preganglionic neurons in nucleus ambiguous relies on persistent sodium current

Aiba, I.; Noebels, J. L.

10.1101/276998 — neuroscience — Posted on 2018-03-06

1788 A learning-based framework for miRNA-disease association prediction using neural networks

Peng, J.; Hui, W.; Li, Q.; Chen, B.; Wei, Z.; Shang, X.

10.1101/276048 — bioinformatics — Posted on 2018-03-06

1789 Scalable cytoarchitectonic characterization of large intact human neocortex samples

Hildebrand, S.; Schueth, A.; Herrler, A.; Galuske, R.; Roebroeck, A.

10.1101/274985 — neuroscience — Posted on 2018-03-05

1790 Reconstructing and decoding imagined letters from early visual cortex using ultra-high field fMRI

Senden, M.; Emmerling, T. C.; Van Hoof, R.; Frost, M.; Goebel, R.

10.1101/277020 — neuroscience — Posted on 2018-03-05

1791 Computational Geometry for Modeling Neural Populations: from Visualization to Simulation

de Kamps, M.; Elle Lepperod, M.; Lai, Y. M.

10.1101/275412 — neuroscience — Posted on 2018-03-05

1792 miR-21-5p and miR-30a-5p are identical in human and bovine, have similar isomiR distribution, and cannot be used to identify xenomiR uptake from cow milk

Fromm, B.; Tosar, J. P.; Yu, L.; Halushka, M. K.; Witwer, K. W.

10.1101/275834 — molecular biology — Posted on 2018-03-05

1793 A protocol for single-cell transcriptomics from cryopreserved renal tissue and urine for the Accelerating Medicine Partnership (AMP) RA/SLE network

Rao, D. A.; Berthier, C. C.; Arazi, A.; Davidson, A.; Liu, Y.; Browne, E. P.; Eisenhaure, T. M.; Chicoine, A.; Lieb, D. J.; Smilek, D. E.; Tosta, P.; Lederer, J. A.; Brenner, M. B.; Hildeman, D.; Woodle, E. S.; Wofsy, D.; Anolik, J. H.; Kretzler, M.; Accelerating Medicines Partnership RA/SLE Network, ; Hacohen, N.; Diamond, B.

10.1101/275859 — immunology — Posted on 2018-03-05

1794 A balance index for phylogenetic trees based on quartets

Coronado, T. M.; Mir Torres, A.; Rossello, F.; Valiente, G.

10.1101/276816 — evolutionary biology — Posted on 2018-03-05

1795 Chaos Game Representation: An Alignment-Free Technique for Exploring Evolutionary Relationships of Protein Sequences

Bhoumik, P.; Hughes, A. L.

10.1101/276915 — evolutionary biology — Posted on 2018-03-05

1796 The symbiotic complex of Dendroctonus simplex: implications in the beetle attack and its life cycle

Durand, A.-A.; Constant, P.; Deziel, E.; Guertin, C.

10.1101/276857 — ecology — Posted on 2018-03-05

1797 Rarity and conservation status do not predict vertebrate population trends

Daskalova, G. N.; Myers-Smith, I. H.; Godlee, J. L.

10.1101/272898 — ecology — Posted on 2018-03-05

1798 NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data

Liu, Q.; Georgieva, D. C.; Egli, D.; Wang, K.

10.1101/277178 — bioinformatics — Posted on 2018-03-05

1799 The Tactile Receptive Fields of Freely Moving Caenorhabditis elegans Nematodes

Mazzochette, E. A.; Nekimken, A. L.; Loizeau, F.; Whitworth, J.; Huynh, B.; Goodman, M. B.; Pruitt, B. L.

10.1101/259937 — animal behavior and cognition — Posted on 2018-03-05

1800 Analysis of P granules in vivo and ex vivo

Smith, J.; Seydoux, G.

10.1101/245878 — molecular biology — Posted on 2018-03-05

1801 Perturbation of ubiquitin homeostasis promotes macrophage oxidative defenses

Charbonneau, M.-E.; Passalacqua, K.; Hagen, S.; Showalter, H.; Wobus, C.; O'Riordan, M.

10.1101/276964 — immunology — Posted on 2018-03-05

1802 Vulnerability of invasive glioma cells to lysosomal membrane instabilization

Le Joncour, V.; Hyvönen, M.; Filppu, P.; Turunen, S. P.; Sihto, H.; Burghardt, I.; Joensuu, H.; Tynninen, O.; Jääskeläinen, J. E.; Weller, M.; Lehti, K.; Laakkonen, P.

10.1101/276402 — cancer biology — Posted on 2018-03-05

1803 Voxel-wise T2 relaxometry of Normal Pediatric Brain Development in 326 healthy infants and toddlers.

Fonov, V.; Leppert, I. R.; Pike, B.; Collins, D. L.; Brain Development Cooperative Group,

10.1101/277038 — neuroscience — Posted on 2018-03-05

1804 Mitochondria-derived vesicles deliver antimicrobial payload to control phagosomal bacteria

Abuaita, B.; Schultz, T.; O'Riordan, M.

10.1101/277004 — immunology — Posted on 2018-03-05

1805 A comparison of single-cell trajectory inference methods: towards more accurate and robust tools

Saelens, W.; Cannoodt, R.; Todorov, H.; Saeys, Y.

10.1101/276907 — bioinformatics — Posted on 2018-03-05

1806 Modelling Large, Dynamic, and Heterogeneous Populations Using DNA Libraries

Andrade, H.; Thomas, A. K.; Lin, W.; Reddavide, F. V.; Zhang, Y.

10.1101/276873 — bioinformatics — Posted on 2018-03-05

1807 The AOPOntology: A Semantic Artificial Intelligence Tool for Predictive Toxicology

Burgoon, L. D.

10.1101/276832 — pharmacology and toxicology — Posted on 2018-03-05

1808 Epigallocatechin-3-Gallate Improves Facial Dysmorphology Associated with Down Syndrome

Starbuck, J.; Llambrich, S.; Gonzalez, R.; Albaiges, J.; Sarle, A.; Wouters, J.; Gonzalez, A.; Sevillano, X.; Sharpe, J.; de la Torre, R.; Dierssen, M.; Vande Velde, G.; Martinez-Abadias, N.

10.1101/276493 — pathology — Posted on 2018-03-05

1809 The marked diversity of unique cortical enhancers enables the generation of neuron-specific tools by Enhancer-Driven Gene Expression (EDGE)

Blankvoort, S.; Witter, M. P.; Noonan, J.; Cotney, J.; Kentros, C.

10.1101/276394 — neuroscience — Posted on 2018-03-05

1810 Where and how our brain represents the temporal structure of observed action

Thomas, R. M.; de Sanctis, T.; Gazzola, V.; Keysers, C.

10.1101/276535 — neuroscience — Posted on 2018-03-05

1811 HIV-1 Nefs are cargo-sensitive AP-1 trimerization switches in tetherin and MHC-I downregulation

Morris, K. L.; Buffalo, C. Z.; Sturzel, C. M.; Heusinger, E.; Kirchhoff, F.; Ren, X.; Hurley, J. H.

10.1101/276733 — molecular biology — Posted on 2018-03-05

1812 Long-read sequencing of nascent RNA reveals coupling among RNA processing events

Herzel, L.; Straube, K.; Neugebauer, K. M.

10.1101/230334 — molecular biology — Posted on 2018-03-05

1813 A dengue monovalent vaccine with novel structure provides cross-protection against four serotypes of dengue virus

Chao, D.-Y.; Shen, W.-F.; Galula, J. U.; Liu, J.-H.; Liao, M.- Y.; Huang, C.-H.; Wang, Y.-C.; Wu, H.-C.; Liang, J.-J.; Lin, Y.- L.; Whitney, M. T.; Chang, G.-J. J.; Chen, S.-R.; Wu, S.-R.

10.1101/275685 — microbiology — Posted on 2018-03-05

1814 Conjugation factors controlling F-plasmid antibiotic resistance transmission

Alalam, H.; Graf, F. E.; Palm, M.; Abadikhah, M.; Zackrisson, M.; Mattsson, M.; Hadjineophytou, C.; Persson, L.; Stenberg, S.; Ghiaci, P.; Sunnerhagen, P.; Warringer, J.; Farewell, A.

10.1101/271254 — microbiology — Posted on 2018-03-05

1815 Escherichia coli Lrp regulates one-third of the genome via direct, cooperative, and indirect routes

Kroner, G. M.; Wolfe, M. B.; Freddolino, P.

10.1101/276808 — microbiology — Posted on 2018-03-05

1816 Curating clinically relevant transcripts for the interpretation of sequence variants

DiStefano, M.; Hemphill, S.; Cushman, B.; Bowser, M.; Hynes, E.; Grant, A.; Siegert, R.; Oza, A.; Gonzalez, M.; Amr, S.; Rehm, H.; Abou Tayoun, A.

10.1101/276287 — genomics — Posted on 2018-03-05

1817 Evolutionary inferences about quantitative traits are affected by underlying genealogical discordance

Mendes, F. K.; Fuentes-Gonzalez, J. A.; Schraiber, J. G.; Hahn, M. W.

10.1101/276642 — evolutionary biology — Posted on 2018-03-05

1818 On the regulatory evolution of new genes throughout their life history

Zhou, Q.; Zhang, J.-y.

10.1101/276667 — evolutionary biology — Posted on 2018-03-05

1819 Transgenerational sterility of small RNA genome silencing mutants in response to germ granule dysfunction

Kretovich Billmyre, K.; Heestand, B.; Spichal, M.; Ahmed, S.

10.1101/276782 — developmental biology — Posted on 2018-03-05

1820 MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria size

Lewis, T. L.; Kwon, S.-K.; Lee, A.; Shaw, R.; Polleux, F.

10.1101/276691 — cell biology — Posted on 2018-03-05

1821 Model for breast cancer diversity and spatial heterogeneity

Romero-Arias, J. R.; Ramirez-Santiago, G.; Velasco-Hernandez, J.; Ohm, L.; Hernandez-Rosales, M.

10.1101/276725 — cancer biology — Posted on 2018-03-05

1822 Association of tamoxifen resistance and lipid reprogramming in breast cancer.

Hultsch, S.; Kankainen, M.; Paavolainen, L.; Kovanen, R.-M.; Ikonen, E.; Kangaspeska, S.; Pietiaeinen, V.; Kallioniemi, O.

10.1101/276618 — cancer biology — Posted on 2018-03-05

1823 Dual BRD4 and AURKA Inhibition is Synergistic against MYCN-amplified and nonamplified Neuroblastoma

Felgenhauer, J.; Tomino, L.; Selich-Anderson, J.; Bopp, E.; Shah, N.

10.1101/276840 — cancer biology — Posted on 2018-03-05

1824 Differential variation and expression analysis

Bar, H.; Schifano, E. D.

10.1101/276337 — bioinformatics — Posted on 2018-03-05

1825 Measurement error and variant-calling in deep Illumina sequencing of HIV

Howison, M.; Coetzer, M.; Kantor, R.

10.1101/276576 — bioinformatics — Posted on 2018-03-05

1826 WAVES: a Web Application for Versatile Enhanced bioinformatic Services

Chakiachvili, M.; Arigon Chifolleau, A.-M.; Lefort, V.

10.1101/276485 — bioinformatics — Posted on 2018-03-05

1827 An Algorithmic Information Calculus for Causal Discovery and Reprogramming Systems

Zenil, H.; Kiani, N. A.; Marabita, F.; Deng, Y.; Elias, S.; Schmidt, A.; Ball, G.; Tegner, J.

10.1101/185637 — systems biology — Posted on 2018-03-05

1828 Growth potential of Listeria monocytogenes in twelve different types of RTE salads: impact of food matrix, storage temperature and shelf life

Ziegler, M.; Kent, D. J.; Stephan, R.; Guldimann, C.

10.1101/261552 — microbiology — Posted on 2018-03-05

1829 Barcoding analysis of HIV drug resistance mutations using Oxford Nanopore MinION (ONT) sequencing

Gonzalez, C.; Gondola, J.; Ortiz, A. Y.; Castillo, J. A.; Pascale, J. M.; Martinez, A. A.

10.1101/240077 — genomics — Posted on 2018-03-05

1830 Genome-wide analysis of adolescent psychotic experiences shows genetic overlap with psychiatric disorders

Pain, O.; Dudbridge, F.; Cardno, A. G.; Freeman, D.; Lu, Y.; Lundstrom, S.; Lichtenstein, P.; Ronald, A.

10.1101/265512 — genetics — Posted on 2018-03-05

1831 Signatures of long-term balancing selection in human genomes

Bitarello, B. D.; de Filippo, C.; Teixeira, J. C.; Schmidt, J.; Kleinert, P.; Meyer, D.; Andres, A. M.

10.1101/119529 — genetics — Posted on 2018-03-05

1832 The Aquilegia genome: adaptive radiation and an extraordinarily polymorphic chromosome with a unique history

Filiault, D.; Ballerini, E.; Mandakova, T.; Akoz, G.; Derieg, N.; Schmutz, J.; Jenkins, J.; Grimwood, J.; Shu, S.; Hayes, R.; Hellsten, U.; Barry, K.; Yan, J.; Mihaltcheva, S.; Karafiatova, M.; Nizhynska, V.; Lysak, M.; Hodges, S.; Nordborg, M.

10.1101/264101 — evolutionary biology — Posted on 2018-03-05

1833 An epigenetic biomarker of aging for lifespan and healthspan

Levine, M. E.; Lu, A. T.; Quach, A.; Chen, B.; Assimes, T. L.; Bandinelli, S.; Hou, L.; Baccarelli, A. A.; Stewart, J. D.; Li, Y.; Whitsel, E. A.; Wilson, J. G.; Reiner, A. P.; Aviv, A.; Lohman, K.; Liu, Y.; Ferrucci, L.; Horvath, S.

10.1101/276162 — epidemiology — Posted on 2018-03-05

1834 A plant biodiversity effect resolved to a single genetic locus

Wuest, S. E.; Niklaus, P. A.

10.1101/264960 — ecology — Posted on 2018-03-05

1835 Building a tumor atlas: integrating single-cell RNA-Seq data with spatial transcriptomics in pancreatic ductal adenocarcinoma

Moncada, R.; Wagner, F.; Chiodin, M.; Devlin, J. C.; Baron, M.; Hajdu, C. H.; Simeone, D.; Yanai, I.

10.1101/254375 — cancer biology — Posted on 2018-03-05

1836 Visualizing single-cell RNA-seq datasets with Similarity Weighted Nonnegative Embedding

Wu, Y.; Tamayo, P.; Zhang, K.

10.1101/276261 — bioinformatics — Posted on 2018-03-05

1837 Ferrous iron folds rRNA and mediates translation

Bray, M. S.; Lenz, T. K.; Bowman, J. C.; Petrov, A. S.; Reddi, A. R.; Hud, N. V.; Williams, L. D.; Glass, J. B.

10.1101/256958 — biochemistry — Posted on 2018-03-05

1838 The UBR-1 Ubiquitin Ligase Regulates Glutamate Metabolism to Generate Coordinated Motor Pattern in C. elegans

Chitturi, J.; Hung, W. L.; Abdel Rahman, A. M.; Wu, M.; Lim, M. A.; Calarco, J.; Baran, R.; Huang, X.; Dennis, J. W.; Zhen, M.

10.1101/198994 — neuroscience — Posted on 2018-03-05

1839 Molecular parallelism in fast-twitch muscle proteins in echolocating mammals

Lee, J.-H.; Lewis, K. M.; Moural, T. W.; Kirilenko, B.; Borgonovo, B.; Prange, G.; Koessl, M.; Huggenberger, S.; Kang, C.; Hiller, M.

10.1101/244566 — evolutionary biology — Posted on 2018-03-05

1840 Coadapted genomes and selection on hybrids: Fisher’s geometric model explains a variety of empirical patterns

Simon, A.; Bierne, N.; Welch, J. J.

10.1101/237925 — evolutionary biology — Posted on 2018-03-05

1841 Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of the great crested newt (Triturus cristatus)

Harper, L. R.; Lawson Handley, L.; Hahn, C.; Boonham, N.; Rees, H. C.; Gough, K. C.; Lewis, E.; Adams, I. P.; Brotherton, P.; Phillips, S.; Haenfling, B.

10.1101/215897 — molecular biology — Posted on 2018-03-05

1842 The fungal ligand chitin directly binds and signals inflammation dependent on oligomer size and TLR2

Fuchs, K.; Cardona Gloria, Y.; Wolz, O.-O.; Herster, F.; Sharma, L.; Dillen, C.; Täumer, C.; Dickhöfer, S.; Bittner, Z.; Dang, T.-M.; Singh, A.; Haischer, D.; Schlöffel, M. A.; Koymans, K. J.; Sanmuganantham, T.; Krach, M.; Schilling, N. A.; Frauhammer, F.; Miller, L.; Nürnberger, T.; LeibundGut-Landmann, S.; Gust, A. A.; Macek, B.; Frank, M.; Gouttefangeas, C.; Dela-Cruz, C. S.; Hartl, D.; Weber, A.

10.1101/270405 — immunology — Posted on 2018-03-05

1843 Global characterization of copy number variants in epilepsy patients from whole genome sequencing

Monlong, J.; Girard, S. L.; Meloche, C.; Cadieux-Dion, M.; Andrade, D. M.; Lafreniere, R. G.; Gravel, M.; Spiegelman, D.; Dionne-Laporte, A.; Boelman, C.; Hamdan, F.; Michaud, J. L.; Rouleau, G.; Minassian, B. A.; Bourque, G.; Cossette, P.

10.1101/199224 — genomics — Posted on 2018-03-05

1844 Disentangling genetic overlap between Attention-Deficit/Hyperactivity Disorder, literacy and language

Verhoef, E.; Demontis, D.; Burgess, S.; Shapland, C. Y.; Dale, P. S.; Okbay, A.; Neale, B. M.; Faraone, S. V.; iPSYCH-Broad-PGC ADHD Consortium, ; Stergiakouli, E.; Davey Smith, G.; Fisher, S. E.; Borglum, A.; St Pourcain, B.

10.1101/276527 — genetics — Posted on 2018-03-05

1845 Accelerometry data in health research: challenges and opportunities. Review and examples

Karas, M.; Bai, J.; Straczkiewicz, M.; Harezlak, J.; Glynn, N. W.; Harris, T.; Zipunnikov, V.; Crainiceanu, C.; Urbanek, J. K.

10.1101/276154 — epidemiology — Posted on 2018-03-05

1846 What lies beneath: a spatial mosaic of Zika virus transmission in the 2015-2016 epidemic in Colombia

Perkins, A.; Rodriguez-Barraquer, I.; Manore, C.; Siraj, A.; Espana, G.; Barker, C.; Johansson, M.; Reiner, R.

10.1101/276006 — epidemiology — Posted on 2018-03-05

1847 The impact of surveillance and control on highly pathogenic avian influenza outbreaks in poultry in Dhaka division, Bangladesh

Hill, E. M.; House, T.; Dhingra, M. S.; Kalpravidh, W.; Morzaria, S.; Osmani, M. G.; Brum, E.; Yamage, M.; Kalam, M. A.; Prosser, D. J.; Takekawa, J. Y.; Xiao, X.; Gilbert, M.; Tildesley, M. J.

10.1101/193177 — epidemiology — Posted on 2018-03-05

1848 An improved method for fitting gamma distribution to substitution rate variation among sites

Xia, X.

10.1101/276329 — bioinformatics — Posted on 2018-03-05

1849 FALCON-meta: a method to infer metagenomic composition of ancient DNA

Pratas, D.; Pinho, A. J.; Silva, R. M.; Rodrigues, J. M. O. S.; Hosseini, M.; Caetano, T.; Ferreira, P. J. S. G.

10.1101/267179 — bioinformatics — Posted on 2018-03-05

1850 DensityPath: a level-set algorithm to visualize and reconstruct cell developmental trajectories for large-scale single-cell RNAseq data

Chen, Z.; An, S.; Bai, X.; Gong, F.; Ma, L.; Wan, L.

10.1101/276311 — systems biology — Posted on 2018-03-05

1851 A stress recovery signaling network for enhanced flooding tolerance in Arabidopsis thaliana

Yeung, E.; van Veen, H.; Vashisht, D.; Luiza Sobral Pava, A.; Hummel, M.; Steffens, B.; Steffen-Heins, A.; Sauter, M.; de Vries, M.; Schuurink, R.; Bazin, J.; Bailey-Serres, J.; Voesenek, L.; Sasidharan, R.

10.1101/276519 — plant biology — Posted on 2018-03-05

1852 Simulation of visual perception and learning with a retinal prosthesis

Golden, J. R.; Erickson-Davis, C.; Cottaris, N. P.; Parthasarathy, N.; Rieke, F.; Brainard, D. H.; Wandell, B. A.; Chichilnisky, E. J.

10.1101/206409 — neuroscience — Posted on 2018-03-05

1853 Fusing Mobile Phone Sensing and Brain Imaging to Assess Depression in College Students: A Proof-of-Concept study

Huckins, J. F.; daSilva, A. W.; Wang, R.; Wang, W.; Hedlund, E. L.; Murphy, E. I.; Lopez, R. B.; Rogers, C.; Holtzheimer, P. E.; Kelley, W. M.; Heatherton, T. F.; Campbell, A. T.

10.1101/276568 — neuroscience — Posted on 2018-03-05

1854 Why not record from every channel with a CMOS scanning probe?

Dimitriadis, G.; Neto, J. P.; Aarts, A.; Alexandru, A.; Ballini, M.; Battaglia, F.; Calcaterra, L.; David, F.; Fiath, R.; Frazao, J.; Geerts, J. P.; Gentet, L. J.; Helleputte, N. V.; Holzhammer, T.; Hoof, C. v.; Horvath, D.; Lopes, G.; Maris, E.; Marques-Smith, A.; Marton, G.; Meszena, D.; Mitra, S.; Musa, S.; Neves, H.; Nogueira, J.; Orban, G. A.; Pothof, F.; Putzeys, J.; Raducanu, B.; Ruther, P.; Schroeder, T.; Singer, W.; Tiesinga, P.; Ulbert, I.; Wang, S.; Welkenhuysen, M.; Kampff, A. R.

10.1101/275818 — neuroscience — Posted on 2018-03-05

1855 Ecological selection for small microbial genomes along a temperate-to-thermal soil gradient

Sorensen, J. W.; Dunivin, T. K.; Tobin, T. C.; Shade, A.

10.1101/276584 — microbiology — Posted on 2018-03-05

1856 Transcriptional plasticity evolution in two strains of Spodoptera frugiperda (Lepidoptera: Noctuidae) feeding on alternative host-plants

Orsucci, M.; Mone, Y.; Audiot, P.; Gimenez, S.; Nhim, S.; Nait-Saidi, R.; Frayssinet, M.; Dumont, G.; Pommier, A.; Boudon, J.-P.; Vabre, M.; Rialle, S.; Koual, R.; Kergoat, G. J.; Nagoshi, R. N.; Meagher, R. L.; d'Alencon, E.; Negre, N.

10.1101/263186 — evolutionary biology — Posted on 2018-03-05

1857 Deep learning reveals evolutionary conservation and divergence of sequence properties underlying gene regulatory enhancers across mammals

Chen, L.; Fish, A. E.; Capra, J. A.

10.1101/110676 — evolutionary biology — Posted on 2018-03-05

1858 Bayesian and likelihood placement of fossils on phylogenies from quantitative morphometric data

Parins-Fukuchi, C.

10.1101/275446 — evolutionary biology — Posted on 2018-03-05

1859 Metabolic adjustment enhances food web stability

Quevreux, P.; Brose, U.

10.1101/276550 — ecology — Posted on 2018-03-05

1860 Impact of nutrient cycling on food web stability

Quevreux, P.; Barot, S.; Thebault, E.

10.1101/276592 — ecology — Posted on 2018-03-05

1861 A widespread thermodynamic effect, but maintenance of biological rates through space across life’s major domains

Soerensen, J. G.; White, C. R.; Duffy, G. A.; Chown, S. L.

10.1101/274944 — ecology — Posted on 2018-03-05

1862 Single-cell RNA-Seq Resolves Cellular Heterogeneity and Transcriptional Dynamics in Spermatogonial Stem Cells Establishment

Liao, J.; Ng, S. H.; Tu, J.; Luk, A. C. S.; Qian, Y.; Tang, N. L. S.; Feng, B.; Chan, W.-Y.; Fouchet, P.; Lee, T.-L.

10.1101/194696 — developmental biology — Posted on 2018-03-05

1863 Imputing missing distances in molecular phylogenetics

Xia, X.

10.1101/276345 — bioinformatics — Posted on 2018-03-05

1864 Pointing Errors in Non-Metric Virtual Environments

Muryy, A.; Glennerster, A.

10.1101/273532 — animal behavior and cognition — Posted on 2018-03-05

1865 Chimpanzees but not orangutans display aversive reactions toward their partner receiving a superior reward

Kim, Y.; Choe, J. C.; Jeong, G.; Kim, D.; Tomonaga, M.

10.1101/274803 — animal behavior and cognition — Posted on 2018-03-05

1866 Selective attention modulates surface filling-in

Harrison, W. J.; Ayeni, A. J.; Bex, P. J.

10.1101/221150 — neuroscience — Posted on 2018-03-05

1867 Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer

Berndt, N.; Egners, A.; Mastrobuoni, G.; Vvedenskaya, O.; Fragoulis, A.; Dugourd, A.; Bulik, S.; Pietzke, M.; Bielow, C.; van Gassel, R.; Olde Damink, S.; Erdem, M.; Saez-Rodriguez, J.; Holzhuetter, H.-G.; Kempa, S.; Cramer, T.

10.1101/275040 — systems biology — Posted on 2018-03-05

1868 Cryo-EM structure of alpha-synuclein fibrils

Guerrero-Ferreira, R.; Taylor, N. M. I.; Mona, D.; Ringler, P.; Lauer, M. E.; Riek, R.; Britschgi, M.; Stahlberg, H.

10.1101/276436 — neuroscience — Posted on 2018-03-05

1869 Ultra-parallel ChIP-seq by barcoding of intact nuclei

Arrigoni, L.; Al-Hasani, H.; Ramirez, F.; Panzeri, I.; Ryan, D. P.; Santacruz, D.; Kress, N.; Pospisilik, A. J.; Boenisch, U.; Manke, T.

10.1101/276469 — genomics — Posted on 2018-03-05

1870 A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets

Copic, A.; Antoine-Bally, S.; Gimenez-Andres, M.; La Torre Garay, C.; Antonny, B.; Manni, M. M.; Pagnotta, S.; GUIHOT, J.; Jackson, C. L.

10.1101/276238 — cell biology — Posted on 2018-03-05

1871 ALDH1-positive intratumoral stromal cells indicate epithelial differentiation and good prognosis in prostate cancer

Nastaly, P.; Filipska, M.; Morrissey, C.; Eltze, E.; Semjonow, A.; Brandt, B.; Pantel, K.; Bednarz-Knoll, N.

10.1101/276378 — cancer biology — Posted on 2018-03-05

1872 crsra: A package for Cleaning and Analyzing Coursera Research Export Data

Hadavand, A.; Leek, J.

10.1101/275537 — scientific communication and education — Posted on 2018-03-05

1873 Uncertainpy: A Python toolbox for uncertainty quantification and sensitivity analysis in computational neuroscience.

Tennoe, S.; Halnes, G.; Einevoll, G. T.

10.1101/274779 — neuroscience — Posted on 2018-03-05

1874 Individual Variation in Brain Network Topology and Social Cognitive Ability

Ling, G.; Lee, I.; Guimond, S.; Lutz, O.; Tandon, N.; Ongur, D.; Eack, S.; Lewandowski, K.; Keshavan, M.; Brady, R.

10.1101/275768 — neuroscience — Posted on 2018-03-05

1875 A method for simultaneous targeted mutagenesis of all nuclear rDNA repeats in Saccharomyces cerevisiae using CRISPR-Cas9

Chiou, L.; Armaleo, D.

10.1101/276220 — molecular biology — Posted on 2018-03-05

1876 The contribution of parent-to-offspring transmission of telomeres to the heritability of telomere length in humans

Delgado, D. A.; Zhang, C.; Demanelis, K.; Chen, L. S.; Gao, J.; Roy, S.; Shinkle, J.; Sabarinathan, M.; Argos, M.; Tong, L.; Ahmed, A.; Islam, T.; Rakibuz-Zaman, M.; Sarwar, G.; Shahriar, H.; Rahman, M.; Yanus, M.; Doherty, J. A.; Jasmine, F.; Kibriya, M. G.; Ahsan, H.; Pierce, B. L.

10.1101/276030 — genetics — Posted on 2018-03-05

1877 Selective activation of alternative MYC core promoters by Wnt-responsive enhancers

Bardales, J. A.; Wieser, E.; Kawaji, H.; Murakawa, Y.; Darzacq, X.

10.1101/266387 — genetics — Posted on 2018-03-05

1878 Visualizing single-cell RNA-seq datasets with Similarity Weighted Nonnegative Embedding (SWNE)

Wu, Y.; Tamayo, P.; Zhang, K.

10.1101/276261 — bioinformatics — Posted on 2018-03-05

1879 Scalable approximate Bayesian inference for particle tracking data

Sun, R.; Paninski, L.

10.1101/276253 — bioinformatics — Posted on 2018-03-05

1880 Central dogma rates and the trade-off between precision and economy

Hausser, J.; Mayo, A.; Alon, U.

10.1101/276139 — systems biology — Posted on 2018-03-04

1881 Bistable emergence of oscillations in structured cell populations

Martinez-Corral, R.; Liu, J.; Suel, G.; Garcia-Ojalvo, J.

10.1101/276113 — systems biology — Posted on 2018-03-04

1882 Spatial organization of the somatosensory cortex revealed by cyclic smFISH

Codeluppi, S.; Borm, L. E.; Zeisel, A.; La Manno, G.; van Lunteren, J. A.; Svensson, C. I.; Linnarsson, S.

10.1101/276097 — neuroscience — Posted on 2018-03-04

1883 Modulation of the mTOR pathway in male Lewis rats after morphine self-administration and subsequent extinction training

Ucha, M.; Coria, S. M.; Nunez, A. E.; Santos-Toscano, R.; Roura-Martinez, D.; Fernandez Ruiz, J. J.; Higuera-Matas, A.; Ambrosio, E.

10.1101/276121 — neuroscience — Posted on 2018-03-04

1884 Epiretinal stimulation with local return enhances selectivity at cellular resolution

Fan, V. H.; Grosberg, L. E.; Madugula, S. S.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.

10.1101/275958 — neuroscience — Posted on 2018-03-04

1885 Identification of novel mutations associated with clofazimine resistance in Mycobacterium abscessus

Chen, Y.; Chen, J.; Zhang, S.; Zhang, W.; Zhang, W.; Zhu, M.; Zhang, Y.

10.1101/276022 — microbiology — Posted on 2018-03-04

1886 Working together: cross-priming in two Legionella pneumophila type I-F CRISPR-Cas systems.

Deecker, S. R.; Ensminger, A. W.

10.1101/276188 — microbiology — Posted on 2018-03-04

1887 Transcriptome-wide association studies accounting for co-localization using Egger regression

Barfield, R.; Feng, H.; Gusev, A.; Wu, L.; Zheng, W.; Pasaniuc, B.; Kraft, P.

10.1101/223263 — epidemiology — Posted on 2018-03-04

1888 Kinetochore recruitment of CENP-F illustrates how paralog divergence shapes kinetochore composition and function

Ciossani, G.; Overlack, K.; Petrovic, A.; Huis in 't Veld, P.; Koerner, C.; Wohlgemuth, S.; Maffini, S.; Musacchio, A.

10.1101/276204 — cell biology — Posted on 2018-03-04

1889 Ancient Thioredoxins Evolved to Modern Day Stability-Function Requirement by Altering Native State Ensemble

Modi, T.; Huihui, J.; Ghosh, K.; Ozkan, S. B.

10.1101/275982 — biophysics — Posted on 2018-03-04

1890 Data-driven analysis of biomedical literature suggests broad-spectrum benevolence of culinary herbs and spices

N K, R.; Tuwani, R.; Mukherjee, J.; Bagler, G.

10.1101/276105 — bioinformatics — Posted on 2018-03-04

1891 Deep Genomic Signature for early metastasis prediction in prostate cancer

Sharifi-Noghabi, H.; Liu, Y.; Erho, N.; Shrestha, R.; Alshalalfa, M.; Davicioni, E.; Collins, C. C.; Ester, M.

10.1101/276055 — bioinformatics — Posted on 2018-03-04

1892 CoPhosK: A Method for Comprehensive Kinase Substrate Annotation Using Co-phosphorylation Analysis

Ayati, M.; Wiredja, D.; Schlatzer, D.; Maxwell, S.; Li, M.; Koyuturk, M.; Chance, M.

10.1101/251009 — bioinformatics — Posted on 2018-03-04

1893 The Educage: an automated platform for studying auditory perceptual learning in mice

Maor, I.; Elyada, Y.; Mizrahi, A.

10.1101/273342 — animal behavior and cognition — Posted on 2018-03-04

1894 Directed functional connectivity using dynamic graphical models

Schwab, S.; Harbord, R.; Zerbi, V.; Elliott, L.; Afyouni, S.; Smith, J. Q.; Woolrich, M. W.; Smith, S. M.; Nichols, T. E.

10.1101/198887 — neuroscience — Posted on 2018-03-04

1895 Back pain, mental health and substance use are associated in adolescents

Kamper, S. J.; Michaleff, Z. A.; Campbell, P.; Dunn, K. M.; Yamato, T. P.; Hodder, R. K.; Wiggers, J. H.; Williams, C. M.

10.1101/274605 — epidemiology — Posted on 2018-03-04

1896 MoDentify: a tool for phenotype-driven module identification in multilevel metabolomics networks

Do, K. T.; Rasp, D. J. N.- P.; Kastenmueller, G.; Suhre, K.; Krumsiek, J.

10.1101/275057 — systems biology — Posted on 2018-03-04

1897 Aberrant expression of collagen family genes in the brain regions developing under agonistic interactions in male mice

Smagin, D. A.; Galyamina, A. G.; Kovalenko, I. L.; Babenko, V. N.; Kudryavtseva, N. N.

10.1101/276063 — neuroscience — Posted on 2018-03-04

1898 Genetically regulated human NODAL splice variants are differentially post-transcriptionally processed and functionally distinct

Findlay, S. D.; Bilyk, O.; Lypka, K.; Waskiewicz, A. J.; Postovit, L.-M.

10.1101/276170 — developmental biology — Posted on 2018-03-04

1899 BAR scaffolds drive membrane fission by crowding disordered domains

Snead, W.; Zeno, W.; Kago, G.; Perkins, R.; Richter, J. B.; Lafer, E.; Stachowiak, J.

10.1101/276147 — biophysics — Posted on 2018-03-04

1900 A Convenient Non-harm Cervical Spondylosis Intelligent Identity method based on Machine Learning

Wang, N.; Huang, X.; Rao, Y.; Xiao, J.; Lu, J.; Wang, N.; Cui, L.

10.1101/264663 — bioinformatics — Posted on 2018-03-04

1901 Sex in the wild: how and why field-based studies contribute to solving the problem of sex

Neiman, M.; Meirmans, P.; Schwander, T.; Meirmans, S.

10.1101/235465 — evolutionary biology — Posted on 2018-03-04

1902 Predatory Behavior is Primary Predictor of Movement of Wildland-Urban Cougars

Buderman, F. E.; Hooten, M. B.; Alldredge, M.; Hanks, E. M.; Ivan, J. S.

10.1101/257295 — ecology — Posted on 2018-03-04

1903 Single-cell RNA-Seq Resolves Cellular Heterogeneity and Transcriptional Dynamics in Spermatogonial Stem Cells Establishment

Liao, J.; Ng, S. H.; Tu, J.; Luk, A. C. S.; Qian, Y.; Tang, N. L. S.; Feng, B.; Chan, W.-Y.; Fouchet, P.; Lee, T.-L.

10.1101/194696 — developmental biology — Posted on 2018-03-04

1904 A simple high-throughput approach to identify actionable drug responses in patient-derived tumor organoids

Phan, N.; Hong, J. J.; Tofig, B.; Mapua, M.; Huang, J.; Memarzadeh, S.; Damoiseaux, R.; Soragni, A.

10.1101/138412 — cancer biology — Posted on 2018-03-04

1905 The emerging role of physical modeling in the future of structure determination

Gaalswyk, K.; Muniyat, M. I.; MacCallum, J.

10.1101/228247 — biochemistry — Posted on 2018-03-04

1906 FastSpar: Rapid and scalable correlation estimation for compositional data

Watts, S. C.; Ritchie, S. C.; Inouye, M.; Holt, K. E.

10.1101/272583 — bioinformatics — Posted on 2018-03-03

1907 Deep Learning Predicts Tuberculosis Drug Resistance Status from Whole-Genome Sequencing Data

Chen, M. L.; Doddi, A.; Royer, J.; Freschi, L.; Schito, M.; Ezewudo, M.; Kohane, I. S.; Beam, A.; Farhat, M.

10.1101/275628 — bioinformatics — Posted on 2018-03-03

1908 A synthetic, three-dimensional bone marrow hydrogel

Jansen, L.; McCarthy, T.; Lee, M.; Peyton, S.

10.1101/275842 — bioengineering — Posted on 2018-03-03

1909 Differences in cognitive functions between cytomegalovirus-infected and cytomegalovirus-free university students: a case-control study

Chvatalova, V.; Sebankova, B.; Hrbackova, H.; Turecek, P.; Flegr, J.

10.1101/275792 — neuroscience — Posted on 2018-03-03

1910 Depressiveness and Neuroticism in Bartonella Seropositive and Seronegative Subjects - Preregistered Case-Controls Study

Flegr, J.; Preiss, M.; Balatova, P.

10.1101/275800 — neuroscience — Posted on 2018-03-03

1911 Task-evoked pupil responses reflect internal belief states

Colizoli, O.; de Gee, J. W.; Urai, A.; Donner, T. H.

10.1101/275776 — neuroscience — Posted on 2018-03-03

1912 Age differences in head motion and estimates of cortical morphology

Madan, C. R.

10.1101/275925 — neuroscience — Posted on 2018-03-03

1913 Method for Improving Psychophysical Threshold Estimates by Detecting Sustained Inattention

Rinderknecht, M. D.; Ranzani, R.; Popp, W. L.; Lambercy, O.; Gassert, R.

10.1101/275594 — neuroscience — Posted on 2018-03-03

1914 Task-induced deactivation in diverse brain systems correlates with interindividual differences in distinct autonomic indices

Iacovella, V.; Faes, L.; Hasson, U.

10.1101/275826 — neuroscience — Posted on 2018-03-03

1915 Why not record from every channel with a CMOS scanning probe?

Dimitriadis, G.; Neto, J. P.; Aarts, A.; Alexandru, A.; Ballini, M.; Battaglia, F.; Calcaterra, L.; David, F.; Fiath, R.; Frazao, J.; Geerts, J.; Gentet, L. J.; Helleputte, N. V.; Holzhammer, T.; Hoof, C. v.; Horvath, D.; Lopes, G.; Maris, E.; Marques-Smith, A.; Marton, G.; Meszena, D.; Mitra, S.; Musa, S.; Neves, H.; Nogueira, J.; Orban, G. A.; Pothof, F.; Putzeys, J.; Raducanu, B.; Ruther, P.; Schroeder, T.; Singer, W.; Tiesinga, P.; Ulbert, I.; Wang, S.; Welkenhuysen, M.; Kampff, A. R.

10.1101/275818 — neuroscience — Posted on 2018-03-03

1916 Humidity as a non-pharmaceutical intervention for influenza A

Reiman, J. M.; Das, B.; Sindberg, G.; Urban, M. D.; Hammerlund, M.; Lee, H.; Spring, K.; Lyman-Gingerich, J.; Generous, A.; Koep, T.; Ewing, K.; Lilja, P.; Enders, F.; Ekker, S.; Huskins, W. C.; Fadel, H.; Pierret, C.

10.1101/273870 — microbiology — Posted on 2018-03-03

1917 Bacterial swarming reduces Proteus mirabilis and Vibrio parahaemolyticus cell stiffness and increases β-lactam susceptibility

Auer, G. K.; Oliver, P. M.; Rajendram, M.; Yao, Q.; Jensen, G. J.; Weibel, D. B.

10.1101/275941 — microbiology — Posted on 2018-03-03

1918 The Rumen Metatranscriptome Landscape Reflects Dietary Adaptation and Methanogenesis in Lactating Dairy Cows

Hornung, B.; van den Bogert, B.; Davids, M.; Martins dos Santos, V. A. P.; Plugge, C. M.; Schaap, P. J.; Smidt, H.

10.1101/275883 — microbiology — Posted on 2018-03-03

1919 Assessing the stability of polio eradication after the withdrawal of oral polio vaccine

Famulare, M.; Selinger, C.; McCarthy, K. A.; Eckhoff, P. A.; Chabot-Couture, G.

10.1101/084012 — epidemiology — Posted on 2018-03-03

1920 A critical role for miR-142 in alveolar epithelial lineage formation

Shrestha, A.; Gianni, C.; Nottet, N.; Vasquez-Armendariz, A. I.; Herold, S.; Cordero, J.; Bahadur Singh, I.; Wilhelm, J.; Barreto, G.; Chao, C.-M.; El Agha, E.; Mari, B.; Zhang, J.-S.; Bellusci, S.

10.1101/253229 — developmental biology — Posted on 2018-03-03

1921 Integrating cross-linking experiments with ab initio protein-protein docking

Vreven, T.; Schweppe, D. K.; Chavez, J. D.; Weisbrod, C. R.; Shibata, S.; Zheng, C.; Bruce, J. E.; Weng, Z.

10.1101/275891 — bioinformatics — Posted on 2018-03-03

1922 Automatic Instrument Segmentation in Robot-Assisted Surgery Using Deep Learning

Shvets, A.; Rakhlin, A.; Kalinin, A.; Iglovikov, V.

10.1101/275867 — bioengineering — Posted on 2018-03-03

1923 Universal scaling across biochemical networks on Earth

Kim, H.; Smith, H.; Mathis, C.; Raymond, J.; Walker, S.

10.1101/212118 — systems biology — Posted on 2018-03-03

1924 MoDentify: a tool for phenotype-driven module identification in multilevel metabolomics networks

Do, K. T.; Rasp, D. J. N.- P.; Kastenmueller, G.; Suhre, K.; Krumsiek, J.

10.1101/275057 — systems biology — Posted on 2018-03-03

1925 Algorithmic complexity of EEG for prognosis of neurodegeneration in idiopathic rapid eye movement behavior disorder (RBD)

Ruffini, G.; Ibanez, D.; Kroupi, E.; Gagnon, J.-F.; Montplaisir, J.; Postuma, R. B.; Castellano, M.; Soria-Frisch, A.

10.1101/200543 — neuroscience — Posted on 2018-03-03

1926 Different inhibitory interneuron cell classes make distinct contributions to visual perception

Cone, J. J.; Scantlen, M. D.; Histed, M. H.; Maunsell, J. H. R.

10.1101/275172 — neuroscience — Posted on 2018-03-03

1927 Exploratory re-encoding of Yellow Fever Virus genome: new insights for the design of live-attenuated viruses

Klitting, R.; Riziki, T.; Moureau, G.; Piorkowski, G.; de Lamballerie, X.

10.1101/256610 — microbiology — Posted on 2018-03-03

1928 Atlastins mediate selective autophagy of the endoplasmic reticulum

Liang, J. R.; Lingeman, E.; Ahmed, S.; Corn, J.

10.1101/274530 — cell biology — Posted on 2018-03-03

1929 In vitro transcribed guide RNAs trigger an innate immune response via the RIG-I pathway

Wienert, B.; Shin, J.; Zelin, E.; Pestal, K.; Corn, J. E.

10.1101/275669 — cell biology — Posted on 2018-03-03

1930 SpliceVec: distributed feature representations for splice junction prediction

Dutta, A.; Dubey, T.; Singh, K. K.; Anand, A.

10.1101/183087 — bioinformatics — Posted on 2018-03-03

1931 A 3D model of human skeletal muscle innervated with stem cell-derived motor neurons enables epsilon-subunit targeted myasthenic syndrome studies

Afshar Bakooshli, M.; Lippmann, E. S.; Mulcahy, B.; Tung, K.; Pegoraro, E.; Ahn, H.; Ginsberg, H.; Zhen, M.; Ashton, R. S.; Gilbert, P. M.

10.1101/275545 — bioengineering — Posted on 2018-03-03

1932 The Genetic Intractability Of Symbiodinium microadriaticum To Standard Algal Transformation Methods

Chen, J. E.; Barbrook, A. C.; Cui, G.; Howe, C. J.; Aranda Lastra, M.

10.1101/140616 — molecular biology — Posted on 2018-03-03

1933 On the importance of being stable - evolutionarily frozen species can win in fluctuating environment

Flegr, J.; Ponizil, P.

10.1101/139030 — evolutionary biology — Posted on 2018-03-03

1934 Metabolic and signalling network map integration: application to cross-talk studies and omics data analysis in cancer

Sompairac, N.; Modamio, J.; Barillot, E.; Fleming, R. M. T.; Zinovyev, A.; Kuperstein, I.

10.1101/274902 — systems biology — Posted on 2018-03-03

1935 D,D-muramyl endopeptidase Spr contributes to intrinsic vancomycin resistance in Salmonella enterica serovar Typhimurium

Vestoe, K.; Huseby, D. L.; Wang, H.; Hughes, D.; Rhen, M.

10.1101/274886 — microbiology — Posted on 2018-03-03

1936 Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses NF-kB activation in human gut epithelial cells

O Cuiv, P.; Giria, R.; Hoedt, E. C.; McGuckin, M. A.; Begun, J.; Morrison, M.

10.1101/275719 — microbiology — Posted on 2018-03-03

1937 A mouse model of maternal obesity leads to uterine natural killer (uNK) cell activation and uterine artery remodeling defects

Baltayeva, J.; Castellana, B.; Mara, D.; Christians, J. K.; Beristain, A. G.

10.1101/275503 — immunology — Posted on 2018-03-03

1938 Strong Episodic Selection for Natural Competence for Transformation Due to Host-Pathogen Dynamics

Palmer, N. D.; Cartwright, R. A.

10.1101/275651 — evolutionary biology — Posted on 2018-03-03

1939 The induction of larval resource preference in heterogeneous habitats

Ravi Kumar, V.; Issar, S.; Agashe, D.

10.1101/274852 — ecology — Posted on 2018-03-03

1940 Embracing scale-dependence to achieve a deeper understanding of biodiversity and its change across communities

Chase, J.; McGill, B.; McGlinn, D. J.; May, F.; Blowes, S. A.; Xiao, X.; Knight, T. M.; Purschke, O.; Gotelli, N. J.

10.1101/275701 — ecology — Posted on 2018-03-03

1941 Protease target prediction via matrix factorization

Marini, S.; Vitali, F.; Rampazzi, S.; Demartini, A.; Akutsu, T.

10.1101/275024 — bioinformatics — Posted on 2018-03-03

1942 reactIDR: Evaluation of the statistical reproducibility of high-throughput structural analyses for a robust RNA reactivity classification

Kawaguchi, R.; Kiryu, H.; Iwakiri, J.; Sese, J.

10.1101/275016 — bioinformatics — Posted on 2018-03-03

1943 Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel

Harley, B.; Ngo, M.

10.1101/273763 — bioengineering — Posted on 2018-03-03

1944 A Cross-Platform Comparison of Student’s Perceptions of the Learning Environment in an Introductory Microbiology Course

Ramirez, M. V.; Lee, V. S.; Hamm, L.; Taveirne, M. E.; Lee, A. M.

10.1101/274571 — scientific communication and education — Posted on 2018-03-03

1945 Pleiotropic effects drive correlation between body mass index and cortical myelination

Ronan, L.; Medic, N.; Fletcher, P.

10.1101/274134 — neuroscience — Posted on 2018-03-03

1946 Olfactory Projection Neurons From the Moth Antennal Lobe Lateral Cluster Exhibit Diverse Morphological and Neurophysiological Characteristics

Lee, S.-G.; Fogarty Celestino, C.; Stagg, J.; Kleineidam, C.; Vickers, N.

10.1101/274506 — neuroscience — Posted on 2018-03-03

1947 Visual encoding signals around 200 milliseconds track onset of evidence accumulation during human decision making

Nunez, M. D.; Gosai, A.; Vandekerckhove, J.; Srinivasan, R.

10.1101/275727 — neuroscience — Posted on 2018-03-03

1948 Nonnegligible role of warming-induced soil drying in regulating warming effect on soil respiration

Du, E.

10.1101/273573 — ecology — Posted on 2018-03-03

1949 CELLector: Genomics Guided Selection of Cancer in vitro Models

Najgebauer, H.; Yang, M.; Francies, H.; Stronach, E. A.; Garnett, M. J.; Saez-Rodriguez, J.; Iorio, F.

10.1101/275032 — bioinformatics — Posted on 2018-03-03

1950 Interplay of size and shape in miniaturized land snails

Örstan, A.

10.1101/275636 — zoology — Posted on 2018-03-03

1951 LIPEA: Lipid Pathway Enrichment Analysis

Acevedo, A.; Duran, C.; Ciucci, S.; Gerl, M.; Cannistraci, C. V.

10.1101/274969 — bioinformatics — Posted on 2018-03-03

1952 Predicting improved protein conformations with a temporal deep recurrent neural network

Pfeiffenberger, E.; Bates, P. A.

10.1101/275008 — bioinformatics — Posted on 2018-03-03

1953 Transcriptional variation and divergence of host-finding behaviour in Steinernema carpocapsae infective juveniles

Warnock, N. D.; Cox, D.; McCoy, C.; Morris, R.; Dalzell, J. J.

10.1101/272641 — animal behavior and cognition — Posted on 2018-03-03

1954 Channelrhodopsin variants engage distinct patterns of network activity

Jun, N. Y.; Cardin, J. A.

10.1101/275644 — neuroscience — Posted on 2018-03-03

1955 Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans

Srinivasan, J.; Chute, C. D.; Coyle, V.; Zhang, Y. K.; Rayes, D.; Choi, H. J.; Alkema, M.; Schroeder, F. C.

10.1101/275693 — neuroscience — Posted on 2018-03-03

1956 Quantifying cell densities and biovolumes of phytoplankton communities and functional groups using scanning flow cytometry, machine learning and unsupervised clustering

Thomas, M. K.; Fontana, S.; Reyes, M.; Pomati, F.

10.1101/274357 — ecology — Posted on 2018-03-03

1957 In vitro transcribed guide RNAs trigger an innate immune response via the RIG-I pathway

Weinert, B.; Shin, J.; Zelin, E.; Pestal, K.; Corn, J. E.

10.1101/275669 — cell biology — Posted on 2018-03-03

1958 Bayesian and likelihood placement of fossils on phylogenies from quantitative morphometrics

Parins-Fukuchi, C.

10.1101/275446 — evolutionary biology — Posted on 2018-03-02

1959 A 3D model of human skeletal muscle innervated with stem cell-derived motor neurons enables epsilon-subunit targeted myasthenic syndrome studies

Afshar Bakooshli, M.; Lippmann, E. S.; Mulcahy, B.; Tung, K.; Pegoraro, E.; Ahn, H.; Ginsberg, H.; Zhen, M.; Ashton, R. S.; Gilbert, P. M.

10.1101/275545 — bioengineering — Posted on 2018-03-02

1960 MoDentify: a tool for phenotype-driven module identification in multilevel metabolomics networks

Do, K. T.; Rasp, D. J. N.- P.; Kastenmueller, G.; Suhre, K.; Krumsiek, J.

10.1101/275057 — systems biology — Posted on 2018-03-02

1961 Network-based prediction of protein interactions

Kovacs, I. A.; Luck, K.; Spirohn, K.; Wang, Y.; Pollis, C.; Schlabach, S.; Bian, W.; Kim, D.-K.; Kishore, N.; Hao, T.; Calderwood, M. A.; Vidal, M.; Barabasi, A.-L.

10.1101/275529 — systems biology — Posted on 2018-03-02

1962 OsIQD14 regulates rice grain shape through modulating the microtubule cytoskeleton

Yang, B.-J.; Wendrich, J. R.; De Rybel, B.; Weijers, D.; Xue, H.-W.

10.1101/275552 — plant biology — Posted on 2018-03-02

1963 IQD proteins integrate auxin and calcium signaling to regulate microtubule dynamics during Arabidopsis development

Wendrich, J.; Yang, B.-J.; Mijnhout, P.; Xue, H.-W.; De Rybel, B.; Weijers, D.

10.1101/275560 — plant biology — Posted on 2018-03-02

1964 Distinct and Complementary Functions of Rho kinase isoforms ROCK1 and ROCK2 in Prefrontal Cortex Structural Plasticity

Greathouse, K. M.; Boros, B. D.; Deslauriers, J. F.; Henderson, B. W.; Curtis, K. A.; Gentry, E. G.; Herskowitz, J. H.

10.1101/275404 — neuroscience — Posted on 2018-03-02

1965 BIC Defacing Algorithm

Fonov, V.; Collins, D. L.

10.1101/275453 — neuroscience — Posted on 2018-03-02

1966 Dynamic Control of Hippocampal Spatial Coding Resolution by Local Visual Cues

Bourboulou, R.; Marti, G.; Michon, F.-X.; Nouguier, M.; Robbe, D.; Koenig, J.; Epsztein, J.

10.1101/275420 — neuroscience — Posted on 2018-03-02

1967 Orthogonal dietary niche enables reversible engraftment of a gut bacterial commensal

Kearney, S.; Gibbons, S.; Erdman, S.; Alm, E.

10.1101/275370 — microbiology — Posted on 2018-03-02

1968 Predicting the spectrum of TCR repertoire sharing with a data-driven model of recombination

Elhanati, Y.; Sethna, Z.; Callan, C. G.; Mora, T.; Walczak, A. M.

10.1101/275602 — immunology — Posted on 2018-03-02

1969 Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

Olova, N. N.; Krueger, F.; Andrews, S.; Oxley, D.; Berrens, R. V.; Branco, M. R.; Reik, W.

10.1101/165449 — genomics — Posted on 2018-03-02

1970 Understanding the factors that shape patterns of nucleotide diversity in the house mouse genome

Booker, T. R.; Keightley, P. D.

10.1101/275610 — evolutionary biology — Posted on 2018-03-02

1971 A dense linkage map of Lake Victoria cichlids improved the Pundamilia genome assembly and revealed a major QTL for sex-determination

Feulner, P. G. D.; Schwarzer, J.; Haesler, M. P.; Meier, J. I.; Seehausen, O.

10.1101/275388 — evolutionary biology — Posted on 2018-03-02

1972 Modeling Epidemics in Seed Systems to Guide Management Strategies: The Case of Sweetpotato in Northern Uganda

Andersen, K.; Buddenhagen, C.; Rachkara, P.; Gibson, R.; Kalule, S.; Phillips, D.; Garrett, K.

10.1101/107359 — ecology — Posted on 2018-03-02

1973 Rapid interpretation of clinical exomes using Phenoxome: a computational phenotype-driven approach

Wu, C.; Devkota, B.; Zhao, X.; Baker, S. W.; Niazi, R.; Kajia, C.; Gonzalez, M. A.; Jayaraman, P.; Deardorff, M. A.; Spinner, N. B.; Krantz, I. D.; Santani, A. B.; Abou Tayoun, A. N.; Sarmady, M.

10.1101/275479 — bioinformatics — Posted on 2018-03-02

1974 Decomposing spatially dependent and cell type specific contributions to cellular heterogeneity

Zhu, Q.; Shah, S.; Dries, R.; Cai, L.; Yuan, G.-C.

10.1101/275156 — bioinformatics — Posted on 2018-03-02

1975 Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

Do, K. T.; Wahl, S.; Raffler, J.; Molnos, S.; Laimighofer, M.; Adamsky, J.; Suhre, K.; Strauch, K.; Peters, A.; Gieger, C.; Langenberg, C.; Stewart, I.; Theis, F. J.; Grallert, H.; Kastenmueller, G.; Krumsiek, J.

10.1101/260281 — systems biology — Posted on 2018-03-02

1976 A stable mode of bookmarking by TBP recruits RNA Polymerase II to mitotic chromosomes

Teves, S. S.; An, L.; Bhargava-Shah, A.; Xie, L.; Darzacq, X.; Tjian, R.

10.1101/257451 — molecular biology — Posted on 2018-03-02

1977 Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen binding affinity

Dosenovic, P.; Kara, E. E.; Pettersson, A.-K.; McGuire, A.; Gray, M.; Hartweger, H.; Thientosapol, E. S.; Stamatatos, L.; Nussenzweig, M. C.

10.1101/275438 — immunology — Posted on 2018-03-02

1978 Host range and genetic plasticity explain the co-existence of integrative and extrachromosomal mobile genetic elements

Cury, J.; Oliveira, P.; de la Cruz, F.; Rocha, E.

10.1101/250266 — evolutionary biology — Posted on 2018-03-02

1979 Back pain, mental health and substance use are associated in adolescents

Kamper, S. J.; Michaleff, Z. A.; Campbell, P.; Dunn, K. M.; Yamato, T. P.; Hodder, R. K.; Wiggers, J. H.; Williams, C. M.

10.1101/274605 — epidemiology — Posted on 2018-03-02

1980 Can we use routinely collected hospital and GP data for epidemiological study of common hand conditions? A UK Biobank based validation project

Lane, J. C.; Schnier, C.; Green, J.; Lam, W. L.; Furniss, D.; Sudlow, C.

10.1101/274167 — epidemiology — Posted on 2018-03-02

1981 Thermoneutrality induces skeletal muscle myopathy via brown adipose tissue in an IRF4- and myostatin-dependent manner

Kong, X.; Zhou, P.; Yao, T.; Kazak, L.; Tenen, D.; Lyubetskaya, A.; Dawes, B.; Tsai, L.; Kahn, B.; Spiegelman, B.; Liu, T.; Rosen, E. D.

10.1101/274365 — physiology — Posted on 2018-03-02

1982 Interindividual variability in HRV reactivity: autonomic flexibility or regression to the mean?

Dimitriev, D.; Saperova, E. V.; Indeykina, O. S.; Dimitriev, A. D.

10.1101/274118 — physiology — Posted on 2018-03-02

1983 Chemoreception of Meloidogyne incognita and Caenorhabditis elegans on botanical nematicidals

Sobkowiak, R.; Bojarska, N.; Krzyzaniak, E.; Wagiel, K.; Ntalli, N.

10.1101/274092 — pharmacology and toxicology — Posted on 2018-03-02

1984 Neural Modulation of Social Distance on Third-Party Punishment

Qu, C.; Tang, Z.; Hu, Y.; Zhang, H.; Dreher, J. C.

10.1101/274720 — neuroscience — Posted on 2018-03-02

1985 Retronasal Habituation: Characterization and Impact on Flavor Perception using Time-Intensity

Pellegrino, R.; Atchley, A.; Ali, S.; Shingleton, J.; Luckett, C. R.

10.1101/274514 — neuroscience — Posted on 2018-03-02

1986 Different inhibitory interneuron cell classes make distinct contributions to visual perception

Cone, J. J.; Scantlen, M. D.; Histed, M. H.; Maunsell, J. H. R.

10.1101/275172 — neuroscience — Posted on 2018-03-02

1987 Fluorescence-based detection of natural transformation in drug resistant Acinetobacter baumannii

Godeux, A.-S.; Lupo, A.; Haenni, M.; Guette-Marquet, S.; Wilharm, G.; Laaberki, M.-H.; Charpentier, X.

10.1101/262311 — microbiology — Posted on 2018-03-02

1988 Comparative Analysis of UL16 Mutants Derived from Multiple Strains of HSV-2 and HSV-1 Reveals Species-Specific Requirements for the UL16 Protein

Gao, J.; Yan, X.; Banfield, B.

10.1101/274548 — microbiology — Posted on 2018-03-02

1989 Comparative RNA-seq based transcriptomic analysis of Aspergillus nidulans recombinant strains overproducing heterologous glycoside hydrolases

Calzado, F.; Persinoti, G. F.; Terrasan, C.; Zubieta, M.; Rubio, M.; Contesini, F.; Squina, F.; Damasio, A.

10.1101/241273 — microbiology — Posted on 2018-03-02

1990 Improved genome assembly and annotation for the rock pigeon (Columba livia)

Holt, C.; Campbell, M.; Keays, D.; Edelman, N.; Kapusta, A.; Maclary, E.; Domyan, E.; Suh, A.; Warren, W.; Yandell, M.; Gilbert, T.; Shapiro, M. D.

10.1101/220947 — genomics — Posted on 2018-03-02

1991 Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

Yengo, L.; Sidorenko, J.; Kemper, K. E.; Zheng, Z.; Wood, A. R.; Weedon, M. N.; Frayling, T. M.; Hirschhorn, J.; Yang, J.; Visscher, P. M.; GIANT Consortium,

10.1101/274654 — genetics — Posted on 2018-03-02

1992 Both functional trait divergence and trait plasticity confer polyploid advantage in changing environments

Wei, N.; Cronn, R.; Liston, A.; Ashman, T.-L.

10.1101/274399 — ecology — Posted on 2018-03-02

1993 Architecture of Marine Food Webs: to be or not be a ‘small-world’

Marina, T. I.; Saravia, L. A.; Cordone, G.; Salinas, V.; Doyle, S. R.; Momo, F. R.

10.1101/274415 — ecology — Posted on 2018-03-02

1994 Fallopian tube precursor lesions of serous ovarian carcinoma require L1CAM for dissemination and metastasis

Doberstein, K.; Spivak, R.; Feng, Y.; Stuckelberger, S.; Mills, G. B.; Devins, K. M.; Schwartz, L. E.; Iwanicki, M. P.; Fogel, M.; Altevogt, P.; Drapkin, R.

10.1101/270785 — cancer biology — Posted on 2018-03-02

1995 Development and Validation of a Nomogram Prognostic Model for Small-Cell Lung Cancer Patients

Wang, S.; Yang, L.; Ci, B.; Maclean, M.; Gerber, D.; Xiao, G.; Xie, Y.

10.1101/273029 — cancer biology — Posted on 2018-03-02

1996 Quantifying nucleation in vivo reveals the physical basis of prion-like phase behavior

Khan, T.; Kandola, T.; Wu, J.; Ketter, E.; Venkatesan, S.; Lange, J. J.; Rodriguez Gama, A.; Box, A.; Unruh, J. R.; Cook, M.; Halfmann, R.

10.1101/205690 — biophysics — Posted on 2018-03-02

1997 Continuous Biomarker Assessment by Exhaustive Survival Analysis

Pearce, D. A.; Nirmal, A. J.; Freeman, T. C.; Sims, A. H.

10.1101/208660 — bioinformatics — Posted on 2018-03-02

1998 HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

Kijima, T.; Prince, T. L.; Tigue, M.; Yim, K.; Schwartz, H.; Beebe, K.; Lee, S.; Budzynski, M.; Williams, H.; Trepel, J.; Sistonen, L.; Calderwood, S. K.; Neckers, L.

10.1101/207001 — biochemistry — Posted on 2018-03-02

1999 Immediate early gene activation throughout the brain is associated with dynamic changes in social context

Williamson, C. M.; Klein, I. S.; Lee, W.; Curley, J. P.

10.1101/275495 — animal behavior and cognition — Posted on 2018-03-02

2000 Transcriptional burst initiation and polymerase pause release are key control points of transcriptional regulation

Bartman, C. R.; Keller, C. A.; Giardine, B.; Hardison, R. C.; Blobel, G. A.; Raj, A.

10.1101/275354 — systems biology — Posted on 2018-03-02

2001 Persistent Underrepresentation of Women’s Science in High Profile Journals

Shen, Y. A.; Webster, J. M.; Shoda, Y.; Fine, I.

10.1101/275362 — scientific communication and education — Posted on 2018-03-02

2002 Differential splicing of ANP32A in birds alters its ability to stimulate RNA synthesis by restricted influenza polymerase

Baker, S. F.; Ledwith, M. P.; Mehle, A.

10.1101/274613 — microbiology — Posted on 2018-03-02

2003 Perforin-2 Permeabilizes the Envelope of Phagocytosed Bacteria

Bai, F.; McCormack, R.; Hower, S.; Plano, G. V.; Lichtenheld, M.; Munson, G. P.

10.1101/274878 — immunology — Posted on 2018-03-02

2004 Neo-formation of chromosomes in bacteria

Poirion, O. B.; Lafay, B.

10.1101/264945 — genomics — Posted on 2018-03-02

2005 Cross-regulation between CDK and MAPK control cellular fate

Durandau, E.; Pelet, S.

10.1101/274787 — cell biology — Posted on 2018-03-02

2006 Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.

Bowie, E.; Norris, R.; Anderson, K. V.; Goetz, S.

10.1101/274266 — cell biology — Posted on 2018-03-02

2007 Multiplexed imaging using same species primary antibodies with signal amplification

Wang, Y.; Xie, W.; Kohman, R. E.; Church, G. M.

10.1101/274456 — cell biology — Posted on 2018-03-02

2008 Fractionated follow-up chemotherapy delays the onset of resistance in bone metastatic prostate cancer

Warman, P.; Kaznatcheev, A.; Araujo, A.; Lynch, C.; Basanta, D.

10.1101/274704 — cancer biology — Posted on 2018-03-02

2009 Cryo-EM visualization of an active high open probability CFTR ion channel

Fay, J. F.; Aleksandrov, L. A.; Jensen, T. J.; Cui, L. L.; Kousouros, J. N.; He, L.; Aleksandrov, A. A.; Gingerich, D. S.; Riordan, J.; Chen, J. Z.

10.1101/274316 — biophysics — Posted on 2018-03-02

2010 SeqStruct : A New Amino Acid Similarity Matrix Based on Sequence Correlations and Structural Contacts Yields Sequence-Structure Congruence

Jia, K.; Jernigan, R. L.

10.1101/268904 — bioinformatics — Posted on 2018-03-02

2011 Word and sentence embedding tools to measure semantic similarity of Gene Ontology terms by their definitions

Duong, D.; Ahmad, W. U.; Eskin, E.; Chang, K.-W.; Li, J. J.

10.1101/103648 — bioinformatics — Posted on 2018-03-02

2012 Forget Pixels: Adaptive Particle Representation of Fluorescence Microscopy Images

Cheeseman, B. L.; Günther, U.; Susik, M.; Gonciarz, K.; Sbalzarini, I. F.

10.1101/263061 — bioinformatics — Posted on 2018-03-02

2013 Towards region-specific propagation of protein functions

Koo, D. C. E.; Bonneau, R.

10.1101/275487 — bioinformatics — Posted on 2018-03-02

2014 Deep mutational scanning by FACS-sorting of encapsulated E. coli micro-colonies

Behrendt, L.; Stein, A.; Shah, S. A.; Zengler, K.; Sorensen, S. J.; Lindorff-Larsen, K.; Winther, J. R.

10.1101/274753 — bioengineering — Posted on 2018-03-02

2015 Crowding tunes 3D collagen fibrils and reveals matrix regulation of cancer cell morphogenesis

Han, A.; Ranamukhaarachchi, S.; Velez, D. O.; Kumar, A.; Engler, A. J.; Fraley, S. I.

10.1101/274696 — bioengineering — Posted on 2018-03-02

2016 Critical comparison of ultracentrifugation and a commercial kit for isolation of exosomes derived from glioblastoma and breast cancer cell lines

Bekhradnia, S.; Lund, K.; Bjorseth, K.; Skottvoll, F. S.; Sjaanes Berg, H.; Roos, N.; Thiede, B.; Nystrom, B.; Roberg-Larsen, H.; Lundanes, E.; Wilson, S. R.

10.1101/274910 — biochemistry — Posted on 2018-03-02

2017 Resting-state functional brain connectivity best predicts the personality dimension of openness to experience

Dubois, J.; Galdi, P.; Han, Y.; Paul, L. K.; Adolphs, R.

10.1101/215129 — neuroscience — Posted on 2018-03-02

2018 Invariant errors reveal limitations in motor correction rather than constraints on error sensitivity

Kim, H.; Morehead, J. R.; Parvin, D.; Moazzezi, R.; Ivry, R.

10.1101/189597 — neuroscience — Posted on 2018-03-02

2019 Clearing the FoG: Antifungal tolerance is a subpopulation effect that is distinct from resistance and is associated with persistent candidemia

Rosenberg, A.; Ene, I. V.; Bibi, M.; Zakin, S.; Segal, E. S.; Ziv, N.; Dahan, A.; Colombo, A. L.; Bennett, R. J.; Berman, J. G.

10.1101/206359 — microbiology — Posted on 2018-03-02

2020 Reconciling the clk-1 and aging paradox and categorizing lifespan curves by taking individual specificity into account

Ren, Y.; Zhang, C.; Guo, W.; Zhang, C.

10.1101/213512 — cell biology — Posted on 2018-03-02

2021 Autoinhibition of kinesin-1 is essential to the dendrite-specific localization of Golgi outposts

Kelliher, M. T.; Yue, Y.; Ng, A.; Kamiyama, D.; Huang, B.; Verhey, K. J.; Wildonger, J.

10.1101/275149 — cell biology — Posted on 2018-03-02

2022 Accessibility of the Shine-Dalgarno sequence dictates N-terminal codon bias in E. coli

Bhattacharyya, S.; Jacobs, W. M.; Adkar, B. V.; Yan, J.; Zhang, W.; Shakhnovich, E. I.

10.1101/195727 — biophysics — Posted on 2018-03-02

2023 Probing transcription factor combinatorics in different promoter classes and in enhancers

Vandel, J.; Cassan, O.; Lebre, S.; Lecellier, C.-H.; Brehelin, L.

10.1101/197418 — bioinformatics — Posted on 2018-03-02

2024 Female grant applicants are equally successful when peer reviewers assess the science, but not when they assess the scientist

Witteman, H. O.; Hendricks, M.; Straus, S.; Tannenbaum, C.

10.1101/232868 — scientific communication and education — Posted on 2018-03-02

2025 Spatial photosynthesis modelling sets guidelines to constructing a viable single-cell cytoplasm-to-stroma C4 cycle

Juric, I.; Hibberd, J. M.; Blatt, M.; Burroughs, N. J.

10.1101/274845 — plant biology — Posted on 2018-03-02

2026 Metatranscriptome analysis of the vaginal microbiota reveals potential mechanisms for protection against metronidazole in bacterial vaginosis

Deng, Z.-L.; Gottschick, C.; Bhuju, S.; Masur, C.; Abels, C.; Wagner-Doebler, I.

10.1101/248302 — microbiology — Posted on 2018-03-02

2027 The Medical Genome Reference Bank: a whole-genome data resource of 4,000 healthy elderly individuals. Rationale and cohort design

Lacaze, P.; Pinese, M.; Kaplan, W.; Stone, A.; Brion, M.-J.; Woods, R. L.; McNamara, M.; McNeil, J. J.; Dinger, M. E.; Thomas, D. M.

10.1101/274019 — genomics — Posted on 2018-03-02

2028 Cryptic, extensive and non-random chromosome reorganization revealed by a butterfly chromonome

Hill, J. A.; Neethiraj, R.; Rastas, P.; Clark, N.; Morehouse, N.; de la Paz Celorio-Mancera, M.; Cols, J. C.; Dircksen, H.; Meslin, C.; Sikkink, K.; Vives, M.; Vogel, H.; Wiklund, C.; Boggs, C. L.; Nylin, S.; Wheat, C.

10.1101/233700 — evolutionary biology — Posted on 2018-03-02

2029 CapsidMesh: atomic-detail structured mesh representation of icosahedral viral capsids and the study of their mechanical properties

Alonzo-Velazquez, J. L.; Botello-Rionda, S.; Herrera-Guzman, R.; Carrillo-Tripp, M.

10.1101/221663 — biophysics — Posted on 2018-03-02

2030 Directed Conservative Causal Core Gene Networks

Altay, G.

10.1101/271031 — bioinformatics — Posted on 2018-03-02

2031 Machine learning as an effective method for identifying true SNPs in polyploid plants

Korani, W.; Clevenger, J.; Chu, Y.; Ozias-Akins, P.

10.1101/274407 — bioinformatics — Posted on 2018-03-02

2032 Cortical recruitment determines learning dynamics and strategy

Ceballo, S.; Bourg, J.; Kempf, A.; Piwkowska, Z.; Daret, A.; Deneux, T.; Rumpel, S.; Bathellier, B.

10.1101/274936 — neuroscience — Posted on 2018-03-02

2033 Attention and Emotion-Enhanced Memory: A Systematic Review and Meta-Analysis of Behavioural and Neuroimaging Evidence

Cross, Z. R.; Santamaria, A.; Kohler, M.

10.1101/273920 — neuroscience — Posted on 2018-03-02

2034 Precision inhibitory stimulation of individual-specific cortical hubs slows information processing in humans

Lynch, C. J.; Breeden, A.; Gordon, E. M.; Cherry, J. B.; Turkeltaub, P. E.; Vaidya, C. J.

10.1101/254417 — neuroscience — Posted on 2018-03-02

2035 Dopamine is a double-edged sword: Enhancing memory retrieval performance at the expense of metacognition

Clos, M.; Bunzeck, N.; Sommer, T.

10.1101/274159 — neuroscience — Posted on 2018-03-02

2036 Unsupervised discovery of temporal sequences in high-dimensional datasets, with applications to neuroscience

Mackevicius, E. L.; Bahle, A. H.; Williams, A. H.; Gu, S.; Denissenko, N. I.; Goldman, M. S.; Fee, M. S.

10.1101/273128 — neuroscience — Posted on 2018-03-02

2037 Clustering trees: a visualisation for evaluating clusterings at multiple resolutions

Zappia, L.; Oshlack, A.

10.1101/274035 — bioinformatics — Posted on 2018-03-02

2038 SoS Notebook: An Interactive Multi-Language Data Analysis Environment

Peng, B.; Wang, G.; Ma, J.; Leong, M. C.; Wakefield, C.; Chiu, Y.; Di, D.; Weinstein, J. N.

10.1101/274001 — bioinformatics — Posted on 2018-03-02

2039 How strong are correlations in strongly recurrent neuronal networks?

Darshan, R.; van Vreeswijk, C.; Hansel, D.

10.1101/274480 — neuroscience — Posted on 2018-03-02

2040 PACAP neurons in the ventral premammillary nucleus regulate reproductive function in the female mouse

Ross, R. A.; Leon, S.; Madara, J. C.; Schafer, D.; Fergani, C.; Maguire, C.; Verstegen, A.; Brengle, E.; Kong, D.; Herbison, A.; Kaiser, U.; Lowell, B. B.; Navarro, V. M.

10.1101/274860 — neuroscience — Posted on 2018-03-02

2041 Variability and reliability of effective connectivity within the core default mode network: A longitudinal spectral DCM study

Almgren, H. B. J.; Van de Steen, F.; Kühn, S.; Razi, A.; Friston, K. J.; Marinazzo, D.

10.1101/273565 — neuroscience — Posted on 2018-03-02

2042 Quantifying the unquantifiable: why Hymenoptera -- not Coleoptera -- is the most speciose animal order

Forbes, A. A.; Bagley, R. K.; Beer, M. A.; Hippee, A. C.; Widmayer, H. A.

10.1101/274431 — zoology — Posted on 2018-03-02

2043 Construction of a Genetic Sexing Strain for Aedes albopictus: a promising tool for the development of sterilizing insect control strategies targeting the tiger mosquito

Lebon, C.; Benlali, A.; Atyame, C. M.; Mavingui, P.; Tortosa, P.

10.1101/274712 — genetics — Posted on 2018-03-02

2044 Comprehensive analysis of lung cancer pathology images to discover tumor shape features that predict survival outcome

Wang, S.; Chen, A.; Yang, L.; Cai, L.; Xie, Y.; Fujimoto, J.; Gazdar, A.; Xiao, G.

10.1101/274332 — cancer biology — Posted on 2018-03-02

2045 Analysis of Escherichia coli Flagellin Gene Expression in Simulated Spaceflight Growth Conditions

Hetrick, K.; Juergensmeyer, E.; Henderson, J. O.

10.1101/274621 — microbiology — Posted on 2018-03-02

2046 The homoeologous genes for the Rec8-like meiotic cohesin in wheat: structure, function, and evolutionary implication

Ma, G.; Zhang, W.; Liu, L.; Chao, W.; Gu, Y.-Q.; Qi, L.; Xu, S.; Cai, X.

10.1101/274522 — genetics — Posted on 2018-03-02

2047 Molecular Genetic Analysis of Rbm45/Drbp1: Genomic Structure, Expression, and Evolution

Price, L.; Loewen Faul, A.; Vuchkovska, A.; Lopez, K.; Fast, K.; Eck, A.; Hoferer, D.; Henderson, J. O.

10.1101/274647 — genetics — Posted on 2018-03-02

2048 In Silico Processing of the Complete CRISPR-Cas Spacer Space for Identification of PAM Sequences

Mendoza, B. J.; Trinh, C. T.

10.1101/274670 — bioinformatics — Posted on 2018-03-02

2049 MethylSight: Taking a wider view of lysine methylation through computer-aided discovery to provide insight into the human methyl-lysine proteome

Biggar, K. K.; Ruiz-Blanco, Y. B.; Charih, F.; Fang, Q.; Connolly, J.; Frensemier, K.; Adhikary, H.; Li, S. S. C.; Green, J. R.

10.1101/274688 — biochemistry — Posted on 2018-03-02

2050 Efficient expression of genes in the Drosophila germline using a UAS-promoter free of interference by Hsp70 piRNAs

DeLuca, S. Z.; Spradling, A. C.

10.1101/274589 — developmental biology — Posted on 2018-03-01

2051 Atlastins mediate selective autophagy of the endoplasmic reticulum

Liang, A.; Lingeman, E.; Ahmed, S.; Corn, J.

10.1101/274530 — cell biology — Posted on 2018-03-01

2052 Comparative Analysis of Linear and Nonlinear Dimension Reduction Techniques on Mass Cytometry Data

Konstorum, A.; Vidal, E.; Jekel, N.; Laubenbacher, R.

10.1101/273862 — bioinformatics — Posted on 2018-03-01

2053 Further studies of ion channels in the electroreceptor of the skate through deep sequencing, cloning and cross species comparisons.

Clusin, W. T.; Wu, T.-H.; Shi, L.-F.; Kao, P. N.

10.1101/274449 — neuroscience — Posted on 2018-03-01

2054 Rapid preimplantation genetic screening (PGS) using a handheld, nanopore-based, DNA sequencer

Wei, S.; Weiss, Z. R.; Gaur, P.; Forman, E.; Williams, Z.

10.1101/274563 — genetics — Posted on 2018-03-01

2055 segment_liftover: a Python tool to convert segments between genome assemblies

Gao, B.; Huang, Q.; Baudis, M.

10.1101/274084 — bioinformatics — Posted on 2018-03-01

2056 Somatic maintenance alters selection acting on mutation rate

Rozhok, A.; DeGregori, J.

10.1101/181065 — evolutionary biology — Posted on 2018-03-01

2057 DNA sequence encodes the position of DNA supercoils

Kim, S. H.; Ganji, M.; Torre, J. v. d.; Abbondanzieri, E.; Dekker, C.

10.1101/180414 — biophysics — Posted on 2018-03-01

2058 Dynamic balance between vesicle transport and microtubule growth enables neurite growth

Yadaw, A. S.; Siddiq, M. M.; Rabinovich, V.; Tolentino, R.; Iyengar, R.; Hansen, J.

10.1101/153569 — systems biology — Posted on 2018-03-01

2059 Stochastic satisficing account of confidence in uncertain value-based decisions

Hertz, U.; Bahrami, B.; Keramati, M.

10.1101/107532 — neuroscience — Posted on 2018-03-01

2060 Computational pharmacogenetics of P-glycoprotein mediated antiepileptic drug resistance

Varghese, S.; Palaniappan, A.

10.1101/095059 — bioinformatics — Posted on 2018-03-01

2061 An animal-actuated rotational head-fixation system for 2-photon imaging during 2-d navigation

Voigts, J.; Harnett, M.

10.1101/262543 — neuroscience — Posted on 2018-03-01

2062 Sex- and Context-dependent Effects of Oxytocin on Social Reward Processing

Ma, X.; Zhao, W.; Luo, R.; Zhou, F.; Geng, Y.; Xu, L.; Gao, Z.; Zheng, X.; Becker, B.; Kendrick, K.

10.1101/274027 — neuroscience — Posted on 2018-03-01

2063 mRNA structure dynamics identifies the embryonic RNA regulome

Beaudoin, J.-D.; Novoa, E. M.; Vejnar, C. E.; Yartseva, V.; Takacs, C.; Kellis, M.; Giraldez, A. J.

10.1101/274290 — molecular biology — Posted on 2018-03-01

2064 The Medical Genome Reference Bank: a whole-genome data resource of 4,000 healthy elderly individuals. Rationale and cohort design

Lacaze, P.; Pinese, M.; Kaplan, W.; Stone, A.; Brion, M.-J.; Woods, R. L.; McNamara, M.; McNeil, J. J.; Dinger, M. E.; Thomas, D. M.

10.1101/274019 — genomics — Posted on 2018-03-01

2065 Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells

Viswanatha, R.; Li, Z.; Hu, Y.; Perrimon, N.

10.1101/274464 — genetics — Posted on 2018-03-01

2066 The conserved phosphatase GSP-2/PP1 promotes germline immortality via small RNA-mediated genome silencing during meiosis

Billmyre, K. K.; Doebley, A.-l.; Heestand, B.; Belicard, T.; Sato-Carlton, A.; Flibotte, S.; Simon, M.; Gnazzo, M.; Skop, A.; Moerman, D.; Carlton, P. M.; Sarkies, P.; Ahmed, S.

10.1101/273722 — genetics — Posted on 2018-03-01

2067 Capn5 expression in the healthy and regenerating zebrafish retina

Coomer, C. E.; Morris, A. C.

10.1101/274423 — developmental biology — Posted on 2018-03-01

2068 Multiplexed imaging using same species primary antibodies with signal amplification

Wang, Y.; Xie, W.; Kohman, R. E.; Church, G. M.

10.1101/274456 — cell biology — Posted on 2018-03-01

2069 Electrodiffusion model of synaptic potentials in dendritic spines

Lagache, T.; Jayant, K.; Yuste, R.

10.1101/274373 — biophysics — Posted on 2018-03-01

2070 fastp: an ultra-fast all-in-one FASTQ preprocessor

Chen, S.; Zhou, Y.; Chen, Y.; Gu, J.

10.1101/274100 — bioinformatics — Posted on 2018-03-01

2071 Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes

Ehrhart, F.; Coort, S. L.; Eijssen, L.; Cirillo, E.; Smeets, E.; Bahram Sangani, N.; Evelo, C.; Curfs, L. M. G.

10.1101/274258 — systems biology — Posted on 2018-03-01

2072 Long-term all-optical interrogation of cortical neurons in awake-behaving non-human primates

Ju, N.; Jiang, R.; Macknik, S. L.; Martinez-Conde, S.; Tang, S.

10.1101/274308 — neuroscience — Posted on 2018-03-01

2073 TRPV1 regulates opioid analgesia during inflammation

Basso, L.; Aboushousha, R.; Yong Fan, C.; Iftinca, M.; Melo, H.; Flynn, R.; Agosti, F.; Hollenberg, M.; Thompson, R. J.; Bourinet, E.; Trang, T.; Altier, C.

10.1101/274233 — neuroscience — Posted on 2018-03-01

2074 Repeat-specific functions for the C-terminal domain of RNA polymerase II in budding yeast

Babokhov, M.; Mosaheb, M. M.; Baker, R. W.; Fuchs, S. M.

10.1101/274274 — genetics — Posted on 2018-03-01

2075 Tripartite chromatin localization of budding yeast Shugoshin involves higher-ordered architecture of mitotic chromosomes

Kuo, M.-H.; Deng, X.

10.1101/274241 — genetics — Posted on 2018-03-01

2076 Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.

Bowie, E.; Norris, R.; Anderson, K. V.; Goetz, S.

10.1101/274266 — cell biology — Posted on 2018-03-01

2077 Cytoplasmic translocation of nuclear lysine-specific demethylase-1 (LSD1/KDM1A) in human hepatoma cells is induced by its inhibitors

Yabuta, S.; Shidoji, Y.

10.1101/274050 — cancer biology — Posted on 2018-03-01

2078 Stimulus-responsive self-assembly of enzymatic fractal structures by computational design

Hernandez, N.; Hansen, W.; Zhu, D.; Shea, M.; Khalid, M.; Manichev, V.; Putnis, M.; Chen, M.; Dodge, A.; Yang, L.; Banal, M.; Gustaffson, T.; Feldman, L.; Lee, S.-H.; Wackett, L.; Dai, W.; Khare, S.

10.1101/274183 — biophysics — Posted on 2018-03-01

2079 ACE: A Workbench using Evolutionary Genetic Algorithms for analysing association in TCGA Data

Gilmore, A.; Savage, K. I.; O'Reilly, P.; Roddy, A. C.; Dunne, P. D.; Lawler, M.; McDade, S. S.; Waugh, D. J.; McArt, D. G.

10.1101/274175 — bioinformatics — Posted on 2018-03-01

2080 ARG-miner: A web platform for crowdsourcing-based curation of antibiotic resistance genes

Argoty, G. A. A.; Guron, G. K.; Garner, E.; Riquelme, M. V.; Heath, L.; Pruden, A.; Vikesland, P.; Zhang, L.

10.1101/274282 — bioinformatics — Posted on 2018-03-01

2081 VideoTagger: User-Friendly Software for Annotating Video Experiments of Any Duration

Rennert, P.; Mac Aodha, O.; Piper, M.; Brostow, G.

10.1101/272468 — animal behavior and cognition — Posted on 2018-03-01

2082 Gene networks underlying faster flowering induction in response to far-red light

Pazos Navarro, M.; Ribalta, F. M.; Hurgobin, B.; Croser, J. S.; Kaur, P.

10.1101/234161 — genetics — Posted on 2018-03-01

2083 The Evolution Of Covert Signaling

Smaldino, P. E.; Flamson, T. J.; McElreath, R.

10.1101/132407 — evolutionary biology — Posted on 2018-03-01

2084 The Mathematics of Descriptions in Descriptive Epidemiology

Ozonoff, D.; Pogel, A.

10.1101/273219 — epidemiology — Posted on 2018-03-01

2085 scPipe: a flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data

Tian, L.; Su, S.; Dong, X.; Amann-Zalcenstein, D.; Biben, C.; Seidi, A.; Hilton, D. J.; Naik, S. H.; Ritchie, M. E.

10.1101/175927 — bioinformatics — Posted on 2018-03-01

2086 Scalable preprocessing for sparse scRNA-seq dataexploiting prior knowledge

Mukherjee, S.; Zhang, Y.; Fan, J.; Kannan, S.; Seelig, G.

10.1101/142398 — bioinformatics — Posted on 2018-03-01

2087 N6-methyladenosine Binding Proteins Negatively Regulate HIV-1 Infectivity and Viral Production

Lu, W.; Tirumuru, N.; Koneru, P. C.; Liu, C.; Kvaratskhelia, M.; He, C.; Wu, L.

10.1101/257410 — microbiology — Posted on 2018-03-01

2088 Increased autophagy in ephrinB2 deficient osteocytes is associated with hypermineralized, brittle bones

Vrahnas, C.; Dite, T. A.; Ansari, N.; Crimeen-Irwin, B.; Nguyen, H.; Forwood, M. R.; Hu, Y.; Ikegame, M.; Bambery, K. R.; Petibois, C.; Tobin, M. J.; Smyth, G. K.; Oakhill, J. S.; Martin, T. J.; Sims, N. A.

10.1101/260711 — cell biology — Posted on 2018-03-01

2089 New formula and conversion factor to compute tree species basic wood density from a global wood technology database.

Vieilledent, G.; Fischer, F. J.; Chave, J.; Guibal, D.; Langbour, P.; Gerard, J.

10.1101/274068 — plant biology — Posted on 2018-03-01

2090 miRNAs in platelet-poor blood plasma and purified RNA are highly stable: a confirmatory study

Muth, D. C.; Powell, B. H.; Zhao, Z.; Witwer, K. W.

10.1101/273797 — molecular biology — Posted on 2018-03-01

2091 High-precision CRISPR-Cas9 base editors with minimized bystander and off-target mutations

Gerhke, J. M.; Cervantes, O. R.; Clement, M. K.; Pinello, L.; Joung, J. K.

10.1101/273938 — molecular biology — Posted on 2018-03-01

2092 Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritis

Liu, Y.; Chang, J.-C.; Hon, C.-C.; Fukui, N.; Tanaka, N.; Zhang, Z.; Lee, M. T. M.; Minoda, A.

10.1101/274043 — genomics — Posted on 2018-03-01

2093 Stochastic models of cell invasion with fluorescent cell cycle indicators

Simpson, M. J.; Jin, W.; Vittadello, S. T.; Tambyah, T.; Ryan, J.; Gunasingh, G.; Haass, N.; McCue, S.

10.1101/273995 — biophysics — Posted on 2018-03-01

2094 The Shape of the Ribosome Exit Tunnel Affects Cotranslational Protein Folding

Kudva, R.; Pardo-Avila, F.; Sandhu, H.; Carroni, M.; Bernstein, H. D.; Von Heijne, G.

10.1101/274191 — biochemistry — Posted on 2018-03-01

2095 Small differences in learning speed for different food qualities can drive efficient collective foraging in ant colonies

Oberhauser, F. B.; Koch, A.; Czaczkes, T. J.

10.1101/274209 — animal behavior and cognition — Posted on 2018-03-01

Archive, 2018-03