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Archive, 2017-03

5 Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization
Roberts, B.; Haupt, A.; Tucker, A.; Grancharova, T.; Arakaki, J.; Fuqua, M. A.; Nelson, A.; Hookway, C.; Ludmann, S. A.; Mueller, I. M.; Yang, R.; Horwitz, A. R.; Rafelski, S. M.; Gunawardane, R. N.
10.1101/123042 — cell biology — Posted on 2017-03-31
7 Methicillin resistant Staphylococcus aureus emerged long before the introduction of methicillin in to clinical practice
Harkins, C. P.; Pichon, B.; Doumith, M.; Parkhill, J.; Westh, H.; Tomasz, A.; de Lencastre, H.; Bentley, S. D.; Kearns, A. M.; Holden, M. T.
10.1101/122408 — microbiology — Posted on 2017-03-31
8 Type 1 diabetes genome-wide association analysis with imputation identifies five new risk regions
Cooper, N. J.; Wallace, C.; Burren, O. S.; Cutler, A.; Walker, N.; Todd, J. A.
10.1101/120022 — genomics — Posted on 2017-03-31
11 Quantitative hybrid modeling reveals predictable mechanical stress response of growing tumor spheroids
Van Liedekerke, P.; Neistch, J.; Johann, T.; Alessandri, K.; Nassoy, P.; Drasdo, D.
10.1101/122614 — biophysics — Posted on 2017-03-31
13 Inflated False Negative Rates Undermine Reproducibility In Task-Based fMRI
Lohmann, G.; Stelzer, J.; Mueller, K.; Lacosse, E.; Buschmann, T.; Kumar, V. J.; Grodd, W.; Scheffler, K.
10.1101/122788 — neuroscience — Posted on 2017-03-31
14 Hypocretin underlies the evolution of sleep loss in the Mexican cavefish
Jaggard, J. B.; Stahl, B. A.; Lloyd, E.; Duboue, E. R.; Keene, A. C.
10.1101/122903 — genomics — Posted on 2017-03-31
17 Discovery and reduction of nonspecific activities of the major herbicide-resistance gene BAR
Christ, B.; Hochstrasser, R.; Guyer, L.; Francisco, R.; Aubry, S.; Hoertensteiner, S.; Weng, J.-K.
10.1101/122184 — plant biology — Posted on 2017-03-31
18 Loss And Gain Of Function Experiments Implicate TMEM18 As A Mediator Of The Strong Association Between Genetic Variants At Human Chromosome 2p25.3 And Obesity
Larder, R.; Sim, M. F. M.; Gulati, P.; Antrobus, R.; Tung, Y. C. L.; Rimmington, D.; Ayuso, E.; Polex-Wolf, J.; Lam, B. Y. H.; Dias, C.; Logan, D. W.; Virtue, S.; Bosch, F.; Yeo, G. S. H.; Saudek, V.; O'Rahilly, S.; Coll, A. P.
10.1101/122853 — physiology — Posted on 2017-03-31
21 Learning And Recognition Of Tactile Temporal Sequences By Mice And Humans
Bale, M. R.; Bitzidou, M.; Pitas, A.; Brebner, L.; Khazim, L.; Anagnou, S.; Stevenson, C.; Maravall, M.
10.1101/122887 — neuroscience — Posted on 2017-03-31
22 Concurrent tACS-fMRI Reveals Causal Influence Of Power Synchronized Neural Activity On Resting State fMRI Connectivity
Baechinger, M.; Zerbi, V.; Moisa, M.; Polania, R.; Liu, Q.; Mantini, D.; Ruff, C.; Wenderoth, N.
10.1101/122820 — neuroscience — Posted on 2017-03-31
23 Memory And Perception-based Facial Image Reconstruction
Chang, C.-H.; Nemrodov, D.; Lee, A. C. H.; Nestor, A.
10.1101/122705 — neuroscience — Posted on 2017-03-31
28 Exhaustive capture of biological variation in RNA-seq data through k-mer decomposition
Audoux, J.; Philippe, N.; Chikhi, R.; Salson, M.; Gabriel, M.; Commes, T.; Gautheret, D.
10.1101/122937 — bioinformatics — Posted on 2017-03-31
30 A Site Specific Model And Analysis Of The Neutral Somatic Mutation Rate In Whole-Genome Cancer Data
Bertl, J.; Guo, Q.; Rasmussen, M. J.; Besenbacher, S.; Nielsen, M. M.; Hornshoej, H.; Pedersen, J. S.; Hobolth, A.
10.1101/122879 — bioinformatics — Posted on 2017-03-31
31 HiGlass: Web-based Visual Comparison And Exploration Of Genome Interaction Maps
Kerpedjiev, P.; Abdennur, N.; Lekschas, F.; McCallum, C.; Dinkla, K.; Strobelt, H.; Luber, J. M.; Ouellette, S. B.; Ahzir, A.; Kumar, N.; Hwang, J.; Alver, B. H.; Pfister, H.; Mirny, L. A.; Park, P. J.; Gehlenborg, N.
10.1101/121889 — bioinformatics — Posted on 2017-03-31
33 Worldwide Population Structure Of Escherichia coli Reveals Two Major Subspecies
Kang, Y.; Yuan, L.; He, Z.; Chen, F.; Gao, Z.; Liu, S.; Jia, X.; Ma, Q.; Jin, X.; Fu, R.; Yu, Y.; Luo, C.; Wu, J.; Xiao, J.; Hu, S.; Yu, J.
10.1101/122713 — microbiology — Posted on 2017-03-31
34 Improving genetic diagnosis in Mendelian disease with transcriptome sequencing
Cummings, B. B.; Marshall, J. L.; Tukiainen, T.; Lek, M.; Donkervoort, S.; Foley, A. R.; Bolduc, V.; Waddell, L.; Sandaradura, S.; O'Grady, G. L.; Estrella, E.; Reddy, H. M.; Zhao, F.; Weisburd, B.; Karczewski, K.; O'Donnell-Luria, A.; Birnbaum, D.; Sarkozy, A.; Hu, Y.; Gonorazky, H.; Claeys, K.; Joshi, H.; Bournazos, A.; Oates, E.; Ghaoui, R.; Davis, M.; Laing, N. G.; Topf, A.; GTEx Consortium, ; Beggs, A.; Kang, P. B.; North, K. N.; Straub, V.; Dowling, J.; Muntoni, F.; Clarke, N. F.; Cooper, S. T.; Bonnemann, C. G.; MacArthur, D. G.
10.1101/074153 — genomics — Posted on 2017-03-31
36 Adaptive pathways of coral populations on the Great Barrier Reef
Matz, M. V.; Treml, E. A.; Aglyamova, G. V.; van Oppen, M. J. H.; Bay, L. K.
10.1101/114173 — evolutionary biology — Posted on 2017-03-31
38 A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis
Mishra, A.; Pisco, A.; Oules, B.; Ly, T.; Liakath-Ali, K.; Walko, G.; Viswanathan, P.; Nijjhar, J.; Dunn, S.-J.; Lamond, A.; Watt, F.
10.1101/122580 — cell biology — Posted on 2017-03-31
39 The microprotein Minion controls cell fusion and muscle formation
Zhang, Q.; Vashisht, A.; O'Rourke, J.; Corbel, S. Y.; Moran, R.; Romero, A.; Miraglia, L.; Zhang, J.; Durrant, E.; Schmedt, C.; Sampath, S. C.; Sampath, S. C.
10.1101/122697 — cell biology — Posted on 2017-03-31
40 Multiplex genome editing for synthetic biology in Vibrio natriegens
Dalia, T. N.; Hayes, C. A.; Stolyar, S.; Marx, C. J.; McKinlay, J. B.; Dalia, A. B.
10.1101/122655 — synthetic biology — Posted on 2017-03-31
41 Epidemiology of the multidrug-resistant ST131-H30 subclone among extraintestinal Escherichia coli collected from US children
Miles-Jay, A.; Weissman, S. J.; Adler, A. L.; Tchesnokova, V.; Sokurenko, E. V.; Baseman, J. G.; Zerr, D. M.
10.1101/122416 — epidemiology — Posted on 2017-03-30
42 A mathematical model for Dengue and Chikungunya inMexico.
Baez-Hernandez, N.; Casas-Martinez, M.; Danis-Lozano, R.; Velasco-Hernandez, J. X.
10.1101/122556 — epidemiology — Posted on 2017-03-30
43 The role of N-terminal modification of MeCP2 in the pathophysiology of Rett syndrome
Sheikh, T. I.; Martinez de Paz, A.; Akhtar, S.; Ausio, J.; Vincent, J. B.
10.1101/122564 — genetics — Posted on 2017-03-30
47 Density dependence in demography and dispersal generates fluctuating invasion speeds
Sullivan, L. L.; Li, B.; Miller, T. E. X.; Neubert, M. G.; Shaw, A. K.
10.1101/075002 — ecology — Posted on 2017-03-30
50 Generation And Comparative Analysis Of Full-Length Transcriptomes In Sweetpotato And Its Putative Wild Ancestor I. trifida
Luo, Y.; Ding, N.; Shi, X.; Wu, Y.; Wang, R.; Pei, L.; Xu, R.; Cheng, S.; Lian, Y.; Gao, J.; Wang, A.; Cao, Q.; Tang, J.
10.1101/112425 — plant biology — Posted on 2017-03-30
55 Primary souring: a novel bacteria-free method for sour beer production
Osburn, K.; Amaral, J.; Metcalf, S. R.; Nickens, D. M.; Rogers, C. M.; Sausen, C.; Caputo, R.; Miller, J.; Li, H.; Tennessen, J. M.; Bochman, M. L.
10.1101/121103 — microbiology — Posted on 2017-03-30
56 The Toxoplasma centrocone houses cell cycle regulatory factors
Naumov, A.; Kratzer, S.; Ting, L.-M.; Kim, K.; Suvorova, E. S.; White, M. W.
10.1101/122465 — microbiology — Posted on 2017-03-30
57 Methicillin resistant Staphylococcus aureus emerged long before the introduction of methicillin in to clinical practice
Harkins, C. P.; Pichon, B.; Doumith, M.; Parkhill, J.; Westh, H.; Tomasz, A.; de Lencastre, H.; Bentley, S. D.; Kearns, A. M.; Holden, M. T.
10.1101/122408 — microbiology — Posted on 2017-03-30
59 Aligning single-cell developmental and reprogramming trajectories identifies molecular determinants of reprogramming outcome
Cacchiarelli, D.; Qiu, X.; Srivatsan, S.; Ziller, M.; Overbey, E.; Grimsby, J.; Pokharel, P.; Livak, K.; Li, S.; Meissner, A.; Mikkelsen, T.; Rinn, J.; Trapnell, C.
10.1101/122531 — genomics — Posted on 2017-03-30
60 Migration Of Human Mesenchymal Stem Cells Stimulated With Pulsed Electric Field And The Dynamics Of The Cell Surface Glycosylation
Jezierska-Woźniak, K.; Lipiłski, S.; Grabarczyk, Łukasz; Barczewska, M.; Habich, A.; Wojtkiewicz, J.; Maksymowicz, W.
10.1101/122382 — cell biology — Posted on 2017-03-30
61 Nanoscale Manipulation Of Membrane Curvature For Probing Endocytosis In Live Cells
Zhao, W.; Hanson, L.; Lou, H.-Y.; Akamatsu, M.; Chowdary, P.; Santoro, F.; Marks, J.; Grassart, A.; Drubin, D.; Cui, Y.; Cui, B.
10.1101/122275 — cell biology — Posted on 2017-03-30
62 Cellular Interplay and Cytokine Hierarchy Cause Pathological Cardiac Hypertrophy in RAF1-Mutant Noonan Syndrome
Yin, J. C.; Platt, M. J.; Tian, X.; Wu, X.; Backx, P. H.; Simpson, J. A.; Araki, T.; Neel, B. G.
10.1101/122150 — cell biology — Posted on 2017-03-30
63 A Conformational Checkpoint Between DNA Binding And Cleavage By CRISPR-Cas9
Dagdas, Y. S.; Chen, J. S.; Sternberg, S. H.; Doudna, J. A.; Yildiz, A.
10.1101/122242 — biophysics — Posted on 2017-03-30
69 Targeting mononuclear phagocytes for eradicating intracellular parasites
Rizzello, L.; Robertson, J. D.; Elks, P. M.; Poma, A.; Daneshpour, N.; Prajsnar, T. K.; Evangelopoulos, D.; Ortiz Canseco, J.; Yona, S.; Marriott, H. M.; Dockrell, D. H.; Foster, S.; De Geest, B.; De Koker, S.; McHugh, T.; Renshaw, S. A.; Battaglia, G.
10.1101/119297 — immunology — Posted on 2017-03-30
74 Chromosome Conformation Paints Reveal The Role Of Lamina Association In Genome Organization And Regulation
Luperchio, T. R.; Sauria, M. E.; Wong, X.; Gaillard, M.-C.; Tsang, P.; Pekrun, K.; Ach, R. A.; Yamada, N. A.; Taylor, J.; Reddy, K.
10.1101/122226 — cell biology — Posted on 2017-03-30
76 Repurposed High-Throughput Images Enable Biological Activity Prediction For Drug Discovery
Simm, J.; Klambauer, G.; Arany, A.; Steijaert, M.; Wegner, J. K.; Gustin, E.; Chupakhin, V.; Chong, Y. T.; Vialard, J.; Buijnsters, P.; Velter, I.; Vapirev, A.; Singh, S.; Carpenter, A.; Wuyts, R.; Hochreiter, S.; Moreau, Y.; Ceulemans, H.
10.1101/108399 — pharmacology and toxicology — Posted on 2017-03-30
78 Recent Regulatory Changes Shaped Human Facial and Vocal Anatomy
Gokhman, D.; Agranat-Tamir, L.; Housman, G.; Nissim-Rafinia, M.; Nieves-Colon, M.; Gu, H.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Bontrop, R.; Meissner, A.; Stone, A. C.; Pusey, A. E.; Mjungu, D.; Kandel, L.; Liebergall, M.; Prada, M. E.; Vidal, J. M.; Krause, J.; Yakir, B.; Paabo, S.; Reich, D.; Lalueza-Fox, C.; Marques-Bonet, T.; Meshorer, E.; Carmel, L.
10.1101/106955 — developmental biology — Posted on 2017-03-30
79 The Image Data Resource: A Scalable Platform for Biological Image Data Access, Integration, and Dissemination
Williams, E.; Moore, J.; Li, S. W.; Rustici, G.; Tarkowska, A.; Chessel, A.; Leo, S.; Antal, B.; Ferguson, R. K.; Sarkans, U.; Brazma, A.; Carazo-Salas, R. E.; Swedlow, J. R.
10.1101/089359 — bioinformatics — Posted on 2017-03-30
81 Conditioning by Subthreshold Synaptic Input Changes the Characteristic Firing Pattern of CA3 Hippocampal Neurons
Soldado Magraner, S.; Brandalise, F.; Honnuraiah, S.; Pfeiffer, M.; Gerber, U.; Douglas, R.
10.1101/084152 — neuroscience — Posted on 2017-03-30
86 Plasmodium simium causing human malaria: a zoonosis with outbreak potential in the Rio de Janeiro Brazilian Atlantic forest
Brasil, P.; Zalis, M. G.; de Pina-Costa, A.; Siqueira, A. M.; Bianco Junior, C.; Silva, S.; Areas, A. L. L.; Pelajo-Machado, M.; de Alvarenga, D. A. M.; Santelli, A. C. F. d. S.; Albuquerque, H. G.; Cravo, P.; de Abreu, F. V. S.; Peterka, C. L.; Zanini, G. M.; Suarez-Mutis, M. C.; Pissinatti, A.; Lourenco-de-Oliveira, R.; Brito, C. F. A. d.; Ferreira-da-Cruz, M. d. F.; Culleton, R.; Daniel-Ribeiro, C. T.
10.1101/122127 — genetics — Posted on 2017-03-29
89 Cross-talk between active DNA demethylation, resetting of cellular metabolism and shoot apical growth in poplar bud break
Conde, D.; Perales, M.; Le Gac, A.-L.; Dervinis, C.; Kirst, M.; Maury, S.; Gonzalez-Melendi, P.; Allona, I.
10.1101/122119 — plant biology — Posted on 2017-03-29
92 Intercellular calcium waves are controlled by morphogen signaling during organ development
Wu, Q.; Brodskiy, P.; Narciso, C.; Levis, M.; Chen, J.; Liang, P.; Arredondo-Walsh, N.; Chen, D. Z.; Zartman, J. J.
10.1101/104745 — developmental biology — Posted on 2017-03-29
94 Paternally inherited noncoding structural variants contribute to autism
Brandler, W. M.; Antaki, D.; Gujral, M.; Kleiber, M. L.; Maile, M. S.; Hong, O.; Chapman, T. R.; Tan, S.; Tandon, P.; Pang, T.; Tang, S. C.; Vaux, K. K.; Yang, Y.; Harrington, E.; Juul, S.; Turner, D. J.; Kingsmore, S. F.; Gleeson, J. G.; Kakaradov, B.; Telenti, A.; Venter, J. C.; Corominas, R.; Cormand, B.; Rueda, I.; Messer, K. S.; Nievergelt, C. M.; Arranz, M. J.; Courchesne, E.; Pierce, K.; Muotri, A. R.; Iakoucheva, L. M.; Hervas, A.; Corsello, C.; Sebat, J.
10.1101/102327 — genomics — Posted on 2017-03-29
95 A Systematic Atlas of Chaperome Deregulation Topologies Across the Human Cancer Landscape
Hadizadeh Esfahani, A.; Sverchkova, A.; Saez-Rodriguez, J.; Schuppert, A.; Brehme, M.
10.1101/122044 — systems biology — Posted on 2017-03-29
96 Could Plants Be Sentient?
Calvo, P.; Sahi, V.; Trewavas, A.
10.1101/121731 — plant biology — Posted on 2017-03-29
97 Drosophila Short stop as a paradigm for the role and regulation of spectraplakins
Voelzmann, A.; Liew, Y.-T.; Qu, Y.; Hahn, I.; Melero, C.; Sanchez-Soriano, N.; Prokop, A.
10.1101/122010 — cell biology — Posted on 2017-03-29
102 EMT and MET: necessary or permissive for metastasis?
Jolly, M. K.; Ware, K. E.; Gilja, S.; Somarelli, J. A.; Levine, H.
10.1101/122051 — cancer biology — Posted on 2017-03-29
103 Real-time observation of flexible domain movements in Cas9
Osuka, S.; Isomura, K.; Kajimoto, S.; Komori, T.; Nishimasu, H.; Shima, T.; Nureki, O.; Uemura, S.
10.1101/122069 — biophysics — Posted on 2017-03-29
105 Repurposed High-Throughput Images Enable Biological Activity Prediction For Drug Discovery
Simm, J.; Klambauer, G.; Arany, A.; Steijaert, M.; Wegner, J. K.; Gustin, E.; Chupakhin, V.; Chong, Y. T.; Vialard, J.; Buijnsters, P.; Velter, I.; Vapirev, A.; Singh, S.; Carpenter, A.; Wuyts, R.; Hochreiter, S.; Moreau, Y.; Ceulemans, H.
10.1101/108399 — pharmacology and toxicology — Posted on 2017-03-29
106 Neural Computations Underpinning The Strategic Management Of Influence In Advice Giving
Hertz, U.; Palminteri, S.; Brunetti, S.; Olesen, C.; Frith, C.; Bahrami, B.
10.1101/121947 — neuroscience — Posted on 2017-03-29
110 Genetic Variation In Adaptability And Pleiotropy In Budding Yeast
Jerison, E. R.; Kryazhimskiy, S.; Mitchell, J.; Bloom, J. S.; Kruglyak, L.; Desai, M. M.
10.1101/121749 — evolutionary biology — Posted on 2017-03-29
113 A Di-Acidic Motif Targets Cytoplasmic Proteins For Unconventional Protein Secretion
Cruz-Garcia, D.; Brouwers, N.; Duran, J. M.; Curwin, A. J.; Malhotra, V.
10.1101/122028 — cell biology — Posted on 2017-03-29
116 Canvas SPW: Calling De Novo Copy Number Variants In Pedigrees
Ivakhno, S.; Roller, E.; Colombo, C.; Tedder, P.; Cox, A. J.
10.1101/121939 — bioinformatics — Posted on 2017-03-29
126 Rv3723/LucA coordinates fatty acid and cholesterol uptake in Mycobacterium tuberculosis
VanderVen, B. C.; Nazarova, E. V.; Montague, C. R.; La, T.; Wilburn, K. M.; Sukumar, N.; Lee, W.; Caldwell, S.; Russell, D. G.
10.1101/121780 — microbiology — Posted on 2017-03-29
127 Gene co-expression network connectivity is an important determinant of selective constraint
Mahler, N.; Wang, J.; Terebieniec, B. K.; Ingvarsson, P. K.; Street, N. R.; Hvidsten, T. R.
10.1101/078188 — genetics — Posted on 2017-03-29
131 Patternize: An R Package For Quantifying Color Pattern Variation
Van Belleghem, S. M.; Papa, R.; Ortiz-Zuazaga, H.; Hendrickx, F.; Jiggins, C.; McMillan, W. O.; Counterman, B.
10.1101/121962 — bioinformatics — Posted on 2017-03-29
135 The Readability Of Scientific Texts Is DecreasingOver Time
Plaven-Sigray, P.; Matheson, G. J.; Schiffler, B. C.; Thompson, W. H.
10.1101/119370 — scientific communication and education — Posted on 2017-03-28
136 Differentially regulated orthologs in sorghum and the subgenomes of maize
Zhang, Y.; Ngu, D. W.; Carvalho, D.; Liang, Z.; Qiu, Y.; Roston, R. L.; Schnable, J. C.
10.1101/120303 — genetics — Posted on 2017-03-28
138 Changes In Firing Regularity In The Normal And Impaired Auditory System
Goodman, D. F. M.; Winter, I. M.; Leger, A. C.; de Cheveigne, A.; Lorenzi, C.
10.1101/121707 — neuroscience — Posted on 2017-03-28
140 Characteristics Of Human Encounters And Social Mixing Patterns Relevant To Infectious Diseases Spread By Close Contact: A Survey In Southwest Uganda
le Polain de Waroux, O.; Cohuet, S.; Ndazima, D.; Kucharski, A.; Juan-Giner, A.; Flasche, S.; Tumwesigye, E.; Arinaitwe, R.; Mwanga-Amumpaire, J.; Boum, Y.; Nackers, F.; Checchi, F.; Grais, R. F.; Edmunds, W. J.
10.1101/121665 — epidemiology — Posted on 2017-03-28
141 Predicting The Impact Of Pneumococcal Conjugate Vaccine Programme Options In Vietnam: A Dynamic Transmission Model
le Polain de Waroux, O.; Edmunds, W. J.; Takahashi, K.; Ariyoshi, K.; Mulholland, K.; Goldblatt, D.; Choi, Y.; Anh, D. D.; Yoshida, L. M.; Flasche, S.
10.1101/121640 — epidemiology — Posted on 2017-03-28
144 Localised Dynactin Protects Growing Microtubules To Deliver Oskar mRNA To The Posterior Cortex Of The Drosophila Oocyte
Nieuwburg, R.; Nashchekin, D.; Jakobs, M.; Carter, A.; Khuc Trong, P.; Goldstein, R. E.; St Johnston, D.
10.1101/121590 — cell biology — Posted on 2017-03-28
146 DNA Methylation As A Marker For Prenatal Smoke Exposure In Adults
Richmond, R.; Suderman, M.; Langdon, R.; Relton, C.; Davey Smith, G.
10.1101/121558 — epidemiology — Posted on 2017-03-28
147 Identifying Human Encounters That Shape The Transmission Of Streptococcus Pneumoniae And Other Respiratory Infections
le Polain de Waroux, O.; Flasche, S.; Kucharski, A.; Langendorf, C.; Ndazima, D.; Mwanga-Amumpaire, J.; Grais, R.; Cohuet, S.; Edmunds, W. J.
10.1101/116079 — epidemiology — Posted on 2017-03-28
148 Physical Activity Phenotyping With Activity Bigrams, And Their Association With BMI
Millard, L. A.; Tilling, K.; Lawlor, D. A.; Flach, P. A.; Gaunt, T. R.
10.1101/121145 — epidemiology — Posted on 2017-03-28
150 The Genome Of The Contractile Demosponge Tethya wilhelma And The Evolution Of Metazoan Neural Signalling Pathways
Francis, W. R.; Eitel, M.; Vargas R., S.; Adamski, M.; Haddock, S. H.; Krebs, S.; Blum, H.; Erpenbeck, D.; Worheide, G.
10.1101/120998 — genomics — Posted on 2017-03-28
152 Correcting For Cell-Type Heterogeneity In Epigenome-Wide Association Studies: Premature Analyses And Conclusions
Zheng, S.; Beck, S.; Jaffe, A.; Koestler, D.; Hansen, K.; Houseman, A.; Widschwendter, M.; Irizarry, R.; Teschendorff, A.
10.1101/121533 — bioinformatics — Posted on 2017-03-28
153 Plasmid Profiler: Comparative Analysis of Plasmid Content in WGS Data
Zetner, A.; Cabral, J.; Mataseje, L.; Knox, N.; Mabon, P.; Mulvey, M.; Van Domselaar, G.
10.1101/121350 — bioinformatics — Posted on 2017-03-28
156 Transient Network Synchrony Of The Developing Medial Entorhinal Cortex
Dawitz, J.; Hjorth, J. J.; Kroon, T.; Ruiperez-Alonso, M.; Chandrasekhar, N.; Hartung, H.; Hanganu-Opatz, I.; Mansvelder, H.; Meredith, R.
10.1101/121459 — neuroscience — Posted on 2017-03-28
157 Integrating Patient And Whole Genome Sequencing Data To Provide Insights Into The Epidemiology Of Seasonal Influenza A(H3N2) Viruses
Goldstein, E. J.; Harvey, W. T.; Wilkie, G. S.; Shepherd, S. J.; MacLean, A. R.; Murcia, P. R.; Gunson, R. N.
10.1101/121434 — microbiology — Posted on 2017-03-28
164 An Integrative Framework For Detecting Structural Variations In Cancer Genomes
Dixon, J.; Xu, J.; Dileep, V.; Zhan, Y.; Song, F.; Le, V. T.; Yardimci, G. G.; Chakraborty, A.; Bann, D. V.; Wang, Y.; Clark, R.; Zhang, L.; Yang, H.; Liu, T.; Iyyanki, S.; An, L.; Pool, C.; Sasaki, T.; Mulia, J. C. R.; Ozadam, H.; Lajoie, B. R.; Kaul, R.; Buckley, M.; Lee, K.; Diegel, M.; Pezic, D.; Ernst, C.; Hadjur, S.; Odom, D. T.; Stamatoyannopoulos, J. A.; Broach, J. R.; Hardison, R.; Ay, F.; Noble, W. S.; Dekker, J.; Gilbert, D. M.; Yue, F.
10.1101/119651 — genomics — Posted on 2017-03-28
170 Plasmid Profiler: Comparative Analysis Of Plasmid Content In WGS Data
Zetner, A.; Cabral, J.; Mataseje, L.; Knox, N.; Mabon, P.; Mulvey, M.; Van Domselaar, G.
10.1101/121350 — bioinformatics — Posted on 2017-03-28
174 Biosynthesis of Isonitrile Lipopeptides by Conserved Non-ribosomal Peptide Synthetase Gene Clusters in Actinobacteria
Harris, N. C.; Sato, M.; Herman, N. A.; Twigg, F.; Cai, W.; Liu, J.; Downey, J.; Khalaf, R.; Martin, J.; Koshino, H.; Zhang, W.
10.1101/121228 — biochemistry — Posted on 2017-03-27
175 Poly(A) Binding Protein Nuclear 1 regulates the polyadenylation of key synaptic plasticity genes and plays a role in homeostatic plasticity
Vlatkovic, I.; Sambandan, S.; Tushev, G.; Wang, M.; Epstein, I.; Glock, C.; Fuerst, N.; Cajigas, I.; Schuman, E.
10.1101/121194 — neuroscience — Posted on 2017-03-27
176 The cycad coralloid root contains a diverse endophytic bacterial community with novel biosynthetic gene clusters unique to its microbiome
Cruz-Morales, P.; Corona-Gomez, A.; Selem-Mojica, N.; Perez-Farrera, M. A.; Barona-Gomez, F.; Cibrian Jaramillo, A.
10.1101/121160 — genomics — Posted on 2017-03-27
179 Gating mass cytometry data by deep learning
Li, H.; Shaham, U.; Stanton, K. P.; Yao, Y.; Montgomery, R.; Kluger, Y.
10.1101/054411 — bioinformatics — Posted on 2017-03-27
181 The cycad coralloid root contains a diverse endophytic bacterial community with novel biosynthetic gene clusters unique to its microbiome
Cruz-Morales, P.; Corona-Gomez, A.; Selem-Mojica, N.; Perez-Farrera, M. A.; Barona-Gomez, F.; Cibrian Jaramillo, A.
10.1101/121160 — genomics — Posted on 2017-03-27
182 Regulation of Life Span by the Gut Microbiota in The Short-Lived African Turquoise Killifish
Smith, P.; Willemsen, D.; Popkes, M. L.; Metge, F.; Gandiwa, E.; Reichard, M.; Valenzano, D. R.
10.1101/120980 — genomics — Posted on 2017-03-27
183 Polygenicity And Epistasis Underlie Fitness-Proximal Traits In The Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel
Noble, L. M.; Chelo, I.; Guzella, T.; Afonso, B.; Riccardi, D. D.; Ammerman, P.; Dayarian, A.; Carvalho, S.; Crist, A.; Pino-Querido, A.; Shraiman, B.; Rockman, M. V.; Teotonio, H.
10.1101/120865 — evolutionary biology — Posted on 2017-03-27
185 H+- and Na+- elicited swift changes of the microtubule system in the biflagellated green alga Chlamydomonas
Yi, L.; Visetsouk, M.; Mynlieff, M.; Qin, H.; Lechtreck, K.; Yang, P.; Yang, P.; Yang, P.
10.1101/121137 — cell biology — Posted on 2017-03-27
189 Primary souring: a novel bacteria-free method for sour beer production
Osburn, K.; Amaral, J.; Metcalf, S. R.; Nickens, D. M.; Rogers, C. M.; Sausen, C.; Caputo, R.; Miller, J.; Li, H.; Tennessen, J. M.; Bochman, M. L.
10.1101/121103 — microbiology — Posted on 2017-03-27
194 ClusterEnG: An interactive educational web resource for clustering big data
Manjunath, M.; Zhang, Y.; Yeo, S. H.; Sobh, O.; Russell, N.; Followell, C.; Bushell, C.; Ravaioli, U.; Song, J. S.
10.1101/120915 — bioinformatics — Posted on 2017-03-27
195 Ethoscopes: An Open Platform For High-Throughput Ethomics
Geissmann, Q.; Garcia Rodriguez, L.; Beckwith, E. J.; French, A. S.; Jamasb, A. R.; Gilestro, G. F.
10.1101/113647 — animal behavior and cognition — Posted on 2017-03-27
196 Signatures of long-term balancing selection in human genomes
Bitarello, B. D.; de Filippo, C.; Teixeira, J. C.; Schmidt, J.; Kleinert, P.; Meyer, D.; Andres, A. M.
10.1101/119529 — genomics — Posted on 2017-03-27
197 Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas
Faria, N. R.; Quick, J.; Morales, I.; Theze, J.; de Jesus, J. G.; Giovanetti, M.; Kraemer, M. U. G.; Hill, S. C.; Black, A.; da Costa, A. C.; Franco, L. C.; Silva, S. P.; Wu, C.-H.; Ragwhani, J.; Cauchemez, S.; du Plessis, L.; Verotti, M. P.; Oliveira, W. K.; Carmo, E. H.; Coelho, G. E.; Santelli, A. C. F. E. S.; Vinhal, L. C.; Henriques, C. M. P.; Simpson, J.; Loose, M.; Andersen, K. G.; Grubaugh, N.; Somasekar, S.; Chiu, C. Y.; Lewis-Ximenez, L. L.; Baylis, S. A.; Chieppe, A. O.; Aguiar, S. F.; Fernandes, C. A.; Lemos, P. d. S.; Nascimento, B. L. S.; Monteiro, H. A. d. O.; Siqueira, I. C.; Q
10.1101/105171 — genomics — Posted on 2017-03-27
199 Multidimensional imbalances in cortical circuit activity in Fragile-X Syndrome mice
O'Donnell, C.; Goncalves, J. T.; Portera-Cailliau, C.; Sejnowski, T. J.
10.1101/086363 — neuroscience — Posted on 2017-03-27
200 Conditioning by Subthreshold Synaptic Input Changes the Characteristic Firing Pattern of CA3 Hippocampal Neurons
Soldado Magraner, S.; Brandalise, F.; Honnuraiah, S.; Pfeiffer, M.; Gerber, U.; Douglas, R.
10.1101/084152 — neuroscience — Posted on 2017-03-27
206 Dissecting the genomic heterogeneity of cancer hallmarks’ acquisition with SLAPenrich
Iorio, F.; Garcia-Alonso, L.; Brammeld, J.; Martincorena, I.; Wille, D. R.; McDermott, U.; Saez-Rodriguez, J.
10.1101/077701 — bioinformatics — Posted on 2017-03-27
207 A Map Of Genetic Interactions In Cancer Cells
Rauscher, B.; Heigwer, F.; Henkel, L.; Hielscher, T.; Boutros, M.
10.1101/120964 — systems biology — Posted on 2017-03-27
208 Towards Human Super EEG
Owen, L. L. W.; Manning, J. R.
10.1101/121020 — neuroscience — Posted on 2017-03-27
210 The Genome Of The Contractile Demosponge Tethya wilhelma And The Evolution Of Metazoan Neural Signalling Pathways
Francis, W. R.; Eitel, M.; Vargas, S.; Adamski, M.; Haddock, S. H.; Krebs, S.; Blum, H.; Worheide, G.
10.1101/120998 — genomics — Posted on 2017-03-27
215 Polygenicity And Epistasis Underlie Fitness-Proximal Traits In The Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel
Noble, L. M.; Chelo, I.; Guzella, T.; Afonso, B.; Riccardi, D. D.; Ammerman, P.; Dayarian, A.; Carvalho, S.; Crist, A.; Pino-Querido, A.; Shraiman, B.; Rockman, M. V.; Teotonio, H.
10.1101/120865 — evolutionary biology — Posted on 2017-03-26
217 Distinguishing Signal From Autofluorescence In Cryogenic Correlated Light And Electron Microscopy Of Mammalian Cells
Carter, S. D.; Mageswaran, S. K.; Farino, Z. J.; Mamede, J. I.; Oikonomou, C. M.; Hope, T. J.; Freyberg, Z.; Jensen, G. J.
10.1101/120642 — cell biology — Posted on 2017-03-26
221 Demographic variability in spruce-fir-beech forest stands in Europe
Lagarrigues, G.; Jabot, F.; Zingg, A.; Gegout, J.-C.; Klopcic, M.; Courbaud, B.
10.1101/120675 — ecology — Posted on 2017-03-26
222 Mitochondrial replacement in an iPSC model of Leber Hereditary Optic Neuropathy.
Wong, R.; Lim, S. Y.; Hung, S. S.; Jackson, S.; Khan, S.; Van Bergen, N. J.; De Smit, E.; Liang, H. H.; Kearns, L. S.; Clarke, L.; Mackey, D. A.; Hewitt, A.; Trounce, I. A.; Pebay, A.
10.1101/120659 — cell biology — Posted on 2017-03-26
226 Context-Dependent Attractor Dynamics in Visual Cortex
Tajima, S.; Koida, K.; Tajima, C. I.; Suzuki, H.; Aihara, K.; Komatsu, H.
10.1101/120725 — neuroscience — Posted on 2017-03-26
227 Conditioning by Subthreshold Synaptic Input Changes the Characteristic Firing Pattern of CA3 Hippocampal Neurons
Soldado Magraner, S.; Brandalise, F.; Honnuraiah, S.; Pfeiffer, M.; Gerber, U.; Douglas, R.
10.1101/084152 — neuroscience — Posted on 2017-03-26
228 Recent Regulatory Changes Shaped Human Facial and Vocal Anatomy
Gokhman, D.; Agranat-Tamir, L.; Housman, G.; Nissim-Rafinia, M.; Nieves-Colon, M.; Gu, H.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Bontrop, R.; Meissner, A.; Stone, A. C.; Pusey, A. E.; Mjungu, D.; Kandel, L.; Liebergall, M.; Prada, M. E.; Vidal, J. M.; Krause, J.; Yakir, B.; Paabo, S.; Reich, D.; Lalueza-Fox, C.; Marques-Bonet, T.; Meshorer, E.; Carmel, L.
10.1101/106955 — molecular biology — Posted on 2017-03-26
232 Exome-Capture RNA-Sequencing Of Decade-Old Breast Cancers And Matched Decalcified Bone Metastases Identifies Clinically Actionable Targets
Priedigkeit, N.; Watters, R. J.; Lucas, P. C.; Basudan, A.; Bhargava, R.; Horne, W.; Kolls, J. K.; Fang, Z.; Rosenzweig, M. Q.; Brufsky, A. M.; Weiss, K. R.; Oesterreich, S.; Lee, A. V.
10.1101/120709 — cancer biology — Posted on 2017-03-26
237 Decoding directional genetic dependencies through orthogonal CRISPR/Cas screens
Boettcher, M.; Tian, R.; Blau, J.; Markegard, E.; Wu, D.; Biton, A.; Zaitlen, N.; McCormick, F.; Kampmann, M.; McManus, M. T.
10.1101/120170 — molecular biology — Posted on 2017-03-25
238 Profiling adaptive immune repertoires across multiple human tissues by RNA Sequencing
Mangul, S.; Mandric, I.; Yang, H. T.; Strauli, N.; Montoya, D.; Rotman, J.; Der Wey, W. V.; Ronas, J. R.; Statz, B.; Zelikovsky, A.; Spreafico, R.; Shifman, S.; Zaitlen, N.; Rossetti, M.; Ansel, K. M.; Eskin, E.
10.1101/089235 — immunology — Posted on 2017-03-25
239 De novo BK channel mutation causes epilepsy by regulating voltage-dependent, but not calcium-dependent, activation
Wang, Q. K.; Willemsen, M.; Li, X.; Poschmann, S.; Chen, Q.; Oundjian, N. J.; Snoeijen-Schouwenaars, F. M.; Kamsteeg, E.-J.
10.1101/120543 — biophysics — Posted on 2017-03-25
241 Trace metal imaging of sulfate-reducing bacteria and methanogenic archaea at single-cell resolution by synchrotron X-ray fluorescence imaging
Glass, J. B.; Chen, S.; Dawson, K. S.; Horton, D. R.; Vogt, S.; Ingall, E. D.; Twining, B. S.; Orphan, V. J.
10.1101/087585 — microbiology — Posted on 2017-03-25
242 Evolutionarily Conserved Alternative Splicing Across Monocots
Mei, W.; Boatwright, J. L.; Feng, G.; Schnable, J. C.; Barbazuk, W. B.
10.1101/120469 — bioinformatics — Posted on 2017-03-25
246 Using Mobile Phones As Acoustic Sensors For High-Throughput Surveillance Of Mosquito Ecology
Mukundarajan, H.; Hol, F. J. H.; Castillo, E. A.; Newby, C.; Prakash, M.
10.1101/120519 — ecology — Posted on 2017-03-25
247 Semisynthetic pH-Sensitive Fluorophores For Imaging Exocytosis And Endocytosis
Martineau, M.; Somasundaram, A.; Grimm, J. B.; Gruber, T. D.; Choquet, D.; Taraska, J. W.; Lavis, L. D.; Perrais, D.
10.1101/118505 — cell biology — Posted on 2017-03-25
248 Fast functional annotation of metagenomic shotgun data by DNA alignment to a microbial gene catalog
Brown, S. M.; Hao, Y.; Chen, H.; Laungani, B. P.; Ali, T. A.; Dong, C.; Lijeron, C.; Kim, B.; Krampis, K.; Pei, Z.
10.1101/120402 — bioinformatics — Posted on 2017-03-25
257 Modeling Adaptive and Non-adaptive Responses of Populations to Environmental Change
Coulson, T.; Kendall, B. E.; Barthold, J.; Plard, F.; Schindler, S.; Ozgul, A.; Gaillard, J.-M.
10.1101/090894 — evolutionary biology — Posted on 2017-03-24
258 Three-dimensional actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes
Fritz-Laylin, L. K.; Riel-Mehan, M.; Chen, B.-C.; Lord, S. J.; Goddard, T. D.; Ferrin, T. E.; Johnson, G.; Betzig, E.; Mullins, R. D.
10.1101/120444 — cell biology — Posted on 2017-03-24
259 Evolutionarily Conserved Alternative Splicing Across Monocots
Mei, W.; Boatwright, J. L.; Feng, G.; Schnable, J. C.; Barbazuk, W. B.
10.1101/120469 — bioinformatics — Posted on 2017-03-24
260 Towards the human cellular microRNAome
McCall, M. N.; Kim, M.-S.; Adil, M.; Patil, A. H.; Lu, Y.; Mitchell, C. J.; Leal-Rojas, P.; Xu, J.; Kumar, M.; Dawson, V. L.; Dawson, T. M.; Baras, A. S.; Rosenberg, A. Z.; Arking, D. E.; Burns, K. H.; Pandey, A.; Halushka, M.
10.1101/120394 — genomics — Posted on 2017-03-24
263 Regulatory remodeling in the allo-tetraploid frog Xenopus laevis
Elurbe, D. M.; Paranjpe, S. S.; Georgiou, G.; van Kruijsbergen, I.; Bogdanovic, O.; Gibeaux, R.; Heald, R.; Lister, R.; Huynen, M. A.; van Heeringen, S. J.; Veenstra, G. J. C.
10.1101/120212 — evolutionary biology — Posted on 2017-03-24
265 STAR-Fusion: Fast and Accurate Fusion Transcript Detection from RNA-Seq
Haas, B.; Dobin, A.; Stransky, N.; Li, B.; Yang, X.; Tickle, T.; Bankapur, A.; Ganote, C.; Doak, T.; Pochet, N.; Sun, J.; Wu, C.; Gingeras, T.; Regev, A.
10.1101/120295 — bioinformatics — Posted on 2017-03-24
266 PHATE: A Dimensionality Reduction Method for Visualizing Trajectory Structures in High-Dimensional Biological Data
Moon, K. R.; van Dijk, D.; Wang, Z.; Chen, W.; Hirn, M. J.; Coifman, R. R.; Ivanova, N. B.; Wolf, G.; Krishnaswamy, S.
10.1101/120378 — bioinformatics — Posted on 2017-03-24
268 A personalized, multi-omics approach identifies genes involved in cardiac hypertrophy and heart failure
Santolini, M.; Romay, M. C.; Yukhtman, C. L.; Rau, C. D.; Ren, S.; Saucerman, J. J.; Wang, J. J.; Weiss, J. N.; Wang, Y.; Lusis, A. J.; Karma, A.
10.1101/120329 — systems biology — Posted on 2017-03-24
270 Neuronal brain region-specific DNA methylation andchromatin accessibility are associated with neuropsychiatric disease heritability
Rizzardi, L.; Hickey, P.; Rodriguez, V.; Tryggvadottir, R.; Callahan, C.; Idrizi, A.; Hansen, K.; Feinberg, A. P.
10.1101/120386 — neuroscience — Posted on 2017-03-24
274 Intramolecular dynamics of single molecules in free diffusion
Limouse, C.; Bell, J. C.; Fuller, C. J.; Straight, A. F.; Mabuchi, H.
10.1101/120311 — biophysics — Posted on 2017-03-24
276 ATLAS: Analysis Tools for Low-depth and Ancient Samples
Link, V.; Kousathanas, A.; Veeramah, K.; Sell, C.; Scheu, A.; Wegmann, D.
10.1101/105346 — bioinformatics — Posted on 2017-03-24
277 Ethoscopes: An Open Platform For High-Throughput Ethomics
Geissmann, Q.; Garcia Rodriguez, L.; Beckwith, E. J.; French, A. S.; Jamasb, A. R.; Gilestro, G.
10.1101/113647 — animal behavior and cognition — Posted on 2017-03-24
278 Sorting & Sequencing Flies By Size: Identification Of Novel TOR Regulators And Parameters For Successful Sorting
Strassburger, K.; Zoeller, T.; Sandmann, T.; Leible, S.; Kerr, G.; Boutros, M.; Teleman, A. A.
10.1101/119719 — genetics — Posted on 2017-03-24
281 From word models to executable models of signaling networks using automated assembly
Gyori, B. M.; Bachman, J. A.; Subramanian, K.; Muhlich, J. L.; Galescu, L.; Sorger, P. K.
10.1101/119834 — systems biology — Posted on 2017-03-24
283 The phosphatase PTPRG controls FGFR1 activity and influences sensitivity to FGFR kinase inhibitors
Wesche, J.; Kostas, M.; Haugsten, E. M.; Zhen, Y.; Sorensen, V.; Szybowska, P.; Fiorito, E.; Lorenz, S.; de Souza, G. A.; Wiedlocha, A.
10.1101/120204 — cell biology — Posted on 2017-03-24
285 Human Self-Initiated Action Is Preceded By A Reliable Process Of Noise Reduction
Khalighinejad, N.; Schurger, A.; Desantis, A.; Zmigrod, L.; Haggard, P.
10.1101/120105 — neuroscience — Posted on 2017-03-24
287 Environmental Perturbations Lead To Extensive Directional Shifts In RNA Processing
Richards, A. L.; Watza, D.; Findley, A.; Alazizi, A.; Wen, X.; Pai, A. A.; Pique-Regi, R.; Luca, F.
10.1101/119974 — genomics — Posted on 2017-03-24
288 Type 1 diabetes genome-wide association analysis with imputation identifies five new risk regions
Cooper, N. J.; Wallace, C.; Burren, O. S.; Cutler, A.; Walker, N.; Todd, J. A.
10.1101/120022 — genomics — Posted on 2017-03-24
291 Contribution Of Trans Regulatory eQTL To Cryptic Genetic Variation In C. elegans
Snoek, B.; Sterken, M.; Bevers, R.; Volkers, R.; van't Hof, A.; Brenchley, R.; Riksen, J.; Cossins, A.; Kammenga, J.
10.1101/120147 — genetics — Posted on 2017-03-24
293 External introductions helped drive and sustain the high incidence of HIV-1 in rural KwaZulu-Natal, South Africa
Rasmussen, D.; Wilkinson, E.; Vandormael, A.; Tanser, F.; Pillay, D.; Stadler, T.; de Oliveira, T.
10.1101/119826 — epidemiology — Posted on 2017-03-24
295 Assembling Metagenomes, One Community At A Time
van der Walt, A. J.; Van Goethem, M. W.; Ramond, J.-B.; Makhalanyane, T. P.; Reva, O.; Cowan, D. A.
10.1101/120154 — bioinformatics — Posted on 2017-03-24
297 Ethoscopes: An Open Platform For High-Throughput Ethomics
Geissmann, Q.; Garcia Rodriguez, L.; Beckwith, E. J.; French, A. S.; Jamasb, A. R.; Gilestro, G.
10.1101/113647 — animal behavior and cognition — Posted on 2017-03-24
302 The Cross-Frequency Mediation Mechanism Of Intracortical Information Transactions
Pascual-Marqui, R. D.; Faber, P.; Milz, P.; Kochi, K.; Kinoshita, T.; Nishida, K.; Yoshimura, M.; Kitaura, Y.; Ikeda, S.; Ishii, R.
10.1101/119362 — neuroscience — Posted on 2017-03-23
307 An evolutionary module in central metabolism
Schober, A. F.; Ingle, C.; Park, J. O.; Chen, L.; Rabinowitz, J. D.; Junier, I.; Rivoire, O.; Reynolds, K. A.
10.1101/120006 — systems biology — Posted on 2017-03-23
308 The Rice XA21 Ectodomain Fused to the Arabidopsis EFR Cytoplasmic Domain Confers Resistance to Xanthomonas oryzae pv. oryzae
Thomas, N. C.; Oksenberg, N.; Liu, F.; Caddell, D.; Nalyvayko, A.; Nguyen, Y.; Schwessinger, B.; Ronald, P.
10.1101/119925 — plant biology — Posted on 2017-03-23
311 Escape from bacterial diversity: potential enemy release in invading yellow starthistle (Centaurea solstitialis) microbiomes
Lu-Irving, P.; Harencar, J.; Sounart, H.; Welles, S. R.; Swope, S. M.; Baltrus, D. A.; Dlugosch, K. M.
10.1101/119917 — plant biology — Posted on 2017-03-23
314 Weak epistasis may drive adaptation in recombining bacteria
Arnold, B. J.; Gutmann, M.; Grad, Y.; Sheppard, S. K.; Corander, J.; Lipsitch, M.; Hanage, W. P.
10.1101/119958 — evolutionary biology — Posted on 2017-03-23
317 Genomic analysis of human polymorphisms affecting drug-protein interactions
Pich i Rosello, O.; Vlasova, A. V.; Shichkova, P. A.; Markov, Y.; Vlasov, P. K.; Kondrashov, F. A.
10.1101/119933 — bioinformatics — Posted on 2017-03-23
318 From word models to executable models of signaling networks using automated assembly
Gyori, B. M.; Bachman, J. A.; Subramanian, K.; Muhlich, J. L.; Galescu, L.; Sorger, P. K.
10.1101/119834 — systems biology — Posted on 2017-03-23
319 ModuleDiscoverer: Identification of regulatory modules in protein-protein interaction networks.
Vlaic, S.; Tokarski-Schnelle, C.; Gustafsson, M.; Dahmen, U.; Guthke, R.; Schuster, S.
10.1101/119099 — systems biology — Posted on 2017-03-23
321 Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length
Liu, S.; Ginzberg, M. B.; Patel, N.; Hild, M.; Leung, B.; Chen, Y.-C.; Li, Z.; Chang, N.; Diena, S.; Wang, Y.; Trimble, W.; Wasserman, L.; Jenkins, J.; Kirschner, M. W.; Kafri, R.
10.1101/119867 — cell biology — Posted on 2017-03-23
322 Treating the lungs via the brain: Mechanisms underpinning improvements in breathlessness with pulmonary rehabilitation.
Herigstad, M.; Faull, O.; Hayen, A.; Evans, E.; Hardinge, M.; Wiech, K.; Pattinson, K. T. S.
10.1101/117390 — neuroscience — Posted on 2017-03-23
323 Conserved roles of RECQ-like helicases Sgs1 and BLM in preventing R-loop induced genome instability
Novoa, C. A.; Chang, E. Y.-C.; Aristizabal, M. J.; Coulombe, Y.; Segovia, R.; Shen, Y.; Keong, C.; Jones, S. J.; Masson, J.-Y.; Kobor, M. S.; Stirling, P. C.
10.1101/119677 — cell biology — Posted on 2017-03-23
328 A Molecular Portrait Of De Novo Genes
Vakirlis, N.; Hebert, A. S.; Opulente, D. A.; Achaz, G.; Hittinger, C. T.; Fischer, G.; Coon, J. J.; Lafontaine, I.
10.1101/119768 — evolutionary biology — Posted on 2017-03-23
329 On the mechanism of long-range alignment order of fibroblasts
Li, X.; Balagam, R.; He, T.-F.; Lee, P. P.; Igoshin, O. A.; Levine, H.
10.1101/119669 — biophysics — Posted on 2017-03-23
333 Epidemic network analysis for mitigation of invasive pathogens in seed systems: Potato in Ecuador
Hernandez Nopsa, J. F.; Buddenhagen, C. E.; Andersen, K. F.; Andrade-Piedra, J.; Forbes, G. A.; Kromann, P.; Thomas-Sharma, S.; Useche, P.; Garrett, K. A.
10.1101/107367 — ecology — Posted on 2017-03-23
334 AllSome Sequence Bloom Trees
Sun, C.; Harris, R. S.; Chikhi, R.; Medvedev, P.
10.1101/090464 — bioinformatics — Posted on 2017-03-23
336 Sorting & Sequencing Flies By Size: Identification Of Novel TOR Regulators And Parameters For Successful Sorting
Strassburger, K.; Zoeller, T.; Sandmann, T.; Leible, S.; Kerr, G.; Boutros, M.; Teleman, A.
10.1101/119719 — genetics — Posted on 2017-03-23
340 Assessing The Reliability Of Spike-In Normalization For Analyses Of Single-Cell RNA Sequencing Data
Lun, A. T.; Calero-Nieto, F. J.; Haim-Vilmovsky, L.; Gottgens, B.; Marioni, J. C.
10.1101/119784 — bioinformatics — Posted on 2017-03-23
343 Can Human Embryonic Stem Cell-Derived Stromal Cells Serve A Starting Material For Myoblasts?
Ando, Y.; Saito, M.; Machida, M.; Noro, C.; Takahashi, M.; Toyoda, M.; Umezawa, A.
10.1101/119693 — cell biology — Posted on 2017-03-23
345 The Readability Of Scientific Texts Is DecreasingOver Time
Plaven-Sigray, P.; Matheson, G. J.; Schiffler, B. C.; Thompson, W. H.
10.1101/119370 — scientific communication and education — Posted on 2017-03-22
347 Profiling copy number variation and disease associations from 50,726 DiscovEHR Study exomes
Maxwell, E. K.; Packer, J. S.; O'Dushlaine, C.; McCarthy, S. E.; Hare-Harris, A.; Staples, J.; Gonzaga-Jauregui, C.; Fetterolf, S. N.; Faucett, W. A.; Leader, J. B.; Moreno-De-Luca, A.; Della Gatta, G.; Scollan, M.; Persaud, T.; Penn, J.; Hawes, A.; Bai, X.; Wolf, S.; Lopez, A. E.; Ulloa, R.; Spangel, C.; Chernomorksy, R.; Borecki, I. B.; Dewey, F. E.; Economides, A. N.; Overton, J. D.; Kirchner, H. L.; Murray, M. F.; Ritchie, M. D.; Carey, D. J.; Ledbetter, D. H.; Yancopoulos, G. D.; Shuldiner, A. R.; Baras, A.; Gottesman, O.; Habegger, L.; Martin, C. L.; Reid, J. G.
10.1101/119461 — genomics — Posted on 2017-03-22
353 The Cross-Frequency Mediation Mechanism Of Intracortical Information Transactions
Pascual-Marqui, R. D.; Faber, P.; Milz, P.; Kochi, K.; Kinoshita, T.; Nishida, K.; Yoshimura, M.; Kitaura, Y.; Ikeda, S.; Ishii, R.
10.1101/119362 — neuroscience — Posted on 2017-03-22
354 Assessing real-time Zika risk in the United States
Castro, L. A.; Fox, S. J.; Chen, X.; Liu, K.; Bellan, S. E.; Dimitrov, N. B.; Galvani, A. P.; Meyers, L. A.
10.1101/056648 — epidemiology — Posted on 2017-03-22
355 Cartilage microRNA dysregulation in mouse osteoarthritis overlaps with patient disease candidates
Kung, L. H. W.; Ravi, V.; Rowley, L.; Angelucci, C.; Fosang, A. J.; Bell, K. M.; Little, C. B.; Bateman, J.
10.1101/113456 — cell biology — Posted on 2017-03-22
356 A likelihood ratio test for changes in homeolog expression bias
Smith, R. D.; Kinser, T. J.; Smith, G. D.; Puzey, J. R.
10.1101/119438 — genomics — Posted on 2017-03-22
359 Phandango: an interactive viewer for bacterial population genomics.
Hadfield, J.; Croucher, N. J.; Goater, R. J.; Abudahab, K.; Aanensen, D. M.; Harris, S. R.
10.1101/119545 — bioinformatics — Posted on 2017-03-22
364 Signatures of long-term balancing selection in human genomes
Bitarello, B. D.; de Filippo, C.; Teixeira, J. C.; Schmidt, J.; Kleinert, P.; Meyer, D.; Andres, A. M.
10.1101/119529 — genomics — Posted on 2017-03-22
369 Inflammatory Breast Cancer: a model for investigating cluster-based dissemination
Jolly, M. K.; Boareto, M.; Debeb, B. G.; Aceto, N.; Farach-Carson, M. C.; Woodward, W. A.; Levine, H.
10.1101/119479 — cancer biology — Posted on 2017-03-22
371 Assessing dynamic functional connectivity in heterogeneous samples
Lehmann, B. C. L.; White, S. R.; Henson, R. N.; Cam-CAN, ; Geerligs, L.
10.1101/118968 — neuroscience — Posted on 2017-03-22
372 Cytosolic ribosomes on the surface of mitochondria
Gold, V. A. M.; Chroscicki, P.; Bragoszewski, P.; Chacinska, A.
10.1101/119339 — cell biology — Posted on 2017-03-22
373 Molecular pathway underlying bouton stabilization by Semaphorin4D during inhibitory synapse formation
Frias, C. P.; Bresser, T.; Scheefhals, L.; Hu, H. Y.; van Bergen en Henegouwen, P. M. P.; Hoogenraad, C. C.; Wierenga, C. J.
10.1101/100271 — neuroscience — Posted on 2017-03-22
375 Harmonization Of Multi-Site Diffusion Tensor Imaging Data
Fortin, J.-P.; Parker, D.; Tunc, B.; Watanabe, T.; Elliott, M. A.; Ruparel, K.; Roalf, D. R.; Satterthwaite, T. D.; Gur, R. C.; Gur, R. E.; Schultz, R. T.; Verma, R.; Shinohara, R. T.
10.1101/116541 — neuroscience — Posted on 2017-03-22
378 Gene ORGANizer: Linking Genes to the Organs They Affect
Gokhman, D.; Kelman, G.; Amartely, A.; Gershon, G.; Tsur, S.; Carmel, L.
10.1101/106948 — genetics — Posted on 2017-03-22
380 Destructive Disinfection Of Infected Brood Prevents Systemic Disease Spread In Ant Colonies
Pull, C. D.; Ugelvig, L. V.; Wiesenhofer, F.; Tragust, S.; Schmitt, T.; Brown, M. J.; Cremer, S.
10.1101/116657 — evolutionary biology — Posted on 2017-03-22
381 Trabecular Meshwork Failure In A Model Of Pigmentary Glaucoma
Dang, Y.; Waxman, S.; Wang, C.; Loewen, R. T.; Sun, M.; Loewen, N.
10.1101/118448 — cell biology — Posted on 2017-03-22
383 LncATLAS database for subcellular localisation of long noncoding RNAs
Mas-Ponte, D.; Carlevaro-Fita, J.; Palumbo, E.; Hermoso, T.; Guigo, R.; Johnson, R.
10.1101/116335 — bioinformatics — Posted on 2017-03-22
388 Multi-Tissue DNA Methylation Age Predictor In Mouse
Stubbs, T. M.; Bonder, M. J.; Stark, A.-K.; Krueger, F.; BI Ageing Clock Team, ; von Meyenn, F.; Stegle, O.; Reik, W.
10.1101/119206 — genomics — Posted on 2017-03-22
389 Polygenic scores via penalized regression on summary statistics
Mak, T.; Porsch, R. M.; Choi, S. W.; Zhou, X.; Sham, P. C.
10.1101/058214 — genomics — Posted on 2017-03-22
391 Assessing The Efficiency Of Catch-Up Campaigns For Introduction Of Pneumococcal Conjugate Vaccine; A Modelling Study Based On Data From Kilifi, Kenya
Flasche, S.; Ojal, J.; Le Polain De Waroux, O.; Otiende, M.; O'Brien, K.; Kiti, M.; Nokes, D. J.; Edmunds, W. J.; Scott, J. A. G.
10.1101/118976 — epidemiology — Posted on 2017-03-22
400 The Cross-Frequency Mediation Mechanism Of Intracortical Information Transactions
Pascual-Marqui, R. D.; Faber, P.; Milz, P.; Kochi, K.; Kinoshita, T.; Nishida, K.; Yoshimura, M.; Kitaura, Y.; Ikeda, S.; Ishii, R.
10.1101/119362 — neuroscience — Posted on 2017-03-22
401 Expanding Gene Families Helps Generate The Metabolic Robustness Required For Antibiotic Biosynthesis
Schniete, J. K.; Cruz-Morales, P.; Selem, N.; Fernandez-Martinez, L. T.; Hunter, I. S.; Barona-Gomez, F.; Hoskisson, P.
10.1101/119354 — microbiology — Posted on 2017-03-22
402 Polymersomes Targeting Mononuclear Phagocytes
Rizzello, L.; Robertson, J. D.; Elks, P. M.; Poma, A.; Daneshpour, N.; Prajsnar, T. K.; Evangelopoulos, D.; Ortiz Canseco, J.; Yona, S.; Marriott, H. M.; Dockrell, D. H.; Foster, S.; De Geest, B.; De Koker, S.; McHugh, T.; Renshaw, S. A.; Battaglia, G.
10.1101/119297 — immunology — Posted on 2017-03-22
405 UBiT2: a client-side web-application for gene expression data analysis
Fan, J.; Fan, D.; Slowikowski, K.; Gehlenborg, N.; Kharchenko, P.
10.1101/118992 — bioinformatics — Posted on 2017-03-22
406 Assembly Of Whole-Chromosome Pseudomolecules For Polyploid Plant Genomes Using Outcrossed Mapping Populations
Zhou, C.; Olukolu, B.; Gemenet, D.; Wu, S.; Gruneberg, W.; Cao, M. D.; Fei, Z.; Zeng, Z.-B.; George, A.; Khan, A.; Yencho, C.; Coin, L.
10.1101/119271 — bioinformatics — Posted on 2017-03-22
408 Single-Cell Transcriptome Sequencing Of 18,787 Human Induced Pluripotent Stem Cells Identifies Differentially Primed Subpopulations
Nguyen, Q.; Lukowski, S.; Chiu, H.; Senabouth, A.; Bruxner, T.; Christ, A.; Palpant, N.; Powell, J.
10.1101/119255 — genomics — Posted on 2017-03-22
410 A common haplotype lowers SPI1 (PU.1) expression in myeloid cells and delays age at onset for Alzheimer’s disease
Huang, K.-l.; Marcora, E.; Pimenova, A.; Di Narzo, A.; Kapoor, M.; Jin, S. C.; Harari, O.; Bertelsen, S.; Fairfax, B.; Czajkowski, J.; Chouraki, V.; Grenier-Boley, B.; Bellenguez, C.; Deming, Y.; McKenzie, A.; Raj, T.; Renton, A.; Budde, J.; Smith, A.; Fitzpatrick, A.; Bis, J.; DeStefano, A.; Adams, H.; Ikram, M. A.; van der Lee, S.; Del-Aguila, J.; Fernandez, M.; Ibanez, L.; The International Genomics of Alzheimer's Project, ; The Alzheimer's Disease Neuroimaging Initiative, ; Sims, R.; Escott-Price, V.; Mayeux, R.; Haines, J.; Farrer, L.; Pericak-Vance, M.; Lambert, J. C.; van Duijn, C.; L
10.1101/110957 — neuroscience — Posted on 2017-03-21
425 Assessing dynamic functional connectivity in heterogeneous samples
Lehmann, B. C. L.; White, S. R.; Henson, R. N.; Cam-CAN, ; Geerligs, L.
10.1101/118968 — neuroscience — Posted on 2017-03-21
431 SIMLR: A Tool For Large-Scale Single-Cell Analysis By Multi-Kernel Learning
Wang, B.; Ramazzotti, D.; De Sano, L.; Zhu, J.; Pierson, E.; Batzoglou, S.
10.1101/118901 — bioinformatics — Posted on 2017-03-21
434 Selective sweep analysis using village dogs highlights the pivotal role of the neural crest in dog domestication
Pendleton, A. L.; Shen, F.; Taravella, A. M.; Emery, S.; Veeramah, K. R.; Boyko, A. R.; Kidd, J. M.
10.1101/118794 — evolutionary biology — Posted on 2017-03-21
436 Dynamics Of Dynein At Microtubule Plus-Ends And The Cortex During The Division Of The C. elegans Zygote
Rodriguez Garcia, R.; Chesneau, L.; Pastezeur, S.; Roul, J.; Tramier, M.; Pecreaux, J.
10.1101/118604 — biophysics — Posted on 2017-03-21
437 SmartScope2: Simultaneous Imaging and Reconstruction of Neuronal Morphology
Long, B.; Zhou, Z.; Cetin, A.; Ting, J.; Gwinn, R.; Tasic, B.; Daigle, T.; Lein, E.; Zeng, H.; Saggau, P.; Hawrylycz, M.; Peng, H.
10.1101/118927 — bioinformatics — Posted on 2017-03-21
439 Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts
Bell, J. C.; Jukam, D.; Teran, N. A.; Risca, V. I.; Smith, O. K.; Johnson, W. L.; Skotheim, J.; Greenleaf, W. J.; Straight, A.
10.1101/118786 — genomics — Posted on 2017-03-20
440 MTAG: Multi-Trait Analysis of GWAS
Turley, P.; Walters, R. K.; Maghzian, O.; Okbay, A.; Lee, J. J.; Fontana, M. A.; Nguyen-Viet, T. A.; Furlotte, N. A.; 23andMe Research Team, ; Social Science Genetic Association Consortium, ; Magnusson, P.; Oskarsson, S.; Johannesson, M.; Visscher, P. M.; Laibson, D.; Cesarini, D.; Neale, B.; Benjamin, D. J.
10.1101/118810 — genomics — Posted on 2017-03-20
441 Multiplexing droplet-based single cell RNA-sequencing using natural genetic barcodes
Kang, H. M.; Subramaniam, M.; Targ, S.; Nguyen, M.; Maliskova, L.; Wan, E.; Wong, S.; Byrnes, L.; Lanata, C.; Gate, R.; Mostafavi, S.; Marson, A.; Zaitlen, N.; Criswell, L. A.; Ye, J.
10.1101/118778 — bioinformatics — Posted on 2017-03-20
443 Quantifying climate change impacts emphasises the importance of managing regional threats in the endangered Yellow-eyed penguin
Mattern, T.; Meyer, S.; Ellenberg, U.; Houston, D. M.; Darby, J. T.; Young, M. J.; van Heezik, Y.; Seddon, P. J.
10.1101/066696 — zoology — Posted on 2017-03-20
446 Identification of drug eQTL interactions from repeat transcriptional and environmental measurements in a lupus clinical trial
Davenport, E. E.; Amariuta, T.; Gutierrez-Arcelus, M.; Slowikowski, K.; Westra, H.-J.; Zhang, Y.; Pearson, S.; von Schack, D.; Beebe, J. S.; Bing, N.; Vincent, M. S.; Zhang, B.; Raychaudhuri, S.
10.1101/118703 — genomics — Posted on 2017-03-20
447 Preservation of Chromatin Organization after Acute Loss of CTCF in Mouse Embryonic Stem Cells
Kubo, N.; Ishii, H.; Gorkin, D.; Meitinger, F.; Xiong, X.; Fang, R.; Liu, T.; Ye, Z.; Li, B.; Dixon, J.; Desai, A.; Zhao, H.; Ren, B.
10.1101/118737 — genomics — Posted on 2017-03-20
448 New mutations, old statistical challenges
Barrett, J. C.; Buxbaum, J.; Cutler, D.; Daly, M.; Devlin, B.; Gratten, J.; Hurles, M. E.; Kosmicki, J. A.; Lander, E. S.; MacArthur, D. G.; Neale, B. M.; Roeder, K.; Visscher, P. M.; Wray, N. R.
10.1101/115964 — genetics — Posted on 2017-03-20
449 Deconstructing isolation-by-distance: the genomic consequences of limited dispersal
Aguillon, S.; Fitzpatrick, J. W.; Bowman, R.; Schoech, S. J.; Clark, A. G.; Coop, G.; Chen, N.
10.1101/093989 — evolutionary biology — Posted on 2017-03-20
452 Structural insights into the light-driven auto-assembly process of the water-oxidizing Mn4CaO5-cluster in photosystem II
Zhang, M.; Bommer, M.; Chatterjee, R.; Hussein, R.; Yano, J.; Dau, H.; Kern, J.; Dobbek, H.; Zouni, A.
10.1101/118661 — biochemistry — Posted on 2017-03-20
453 A new organotypic model of synaptic competition reveals activity-dependent localization of C1q
Koyama, R.; Wu, Y.; Bialas, A. R.; Thompson, A.; Welsh, C. A.; Frouin, A.; Chen, C.; Stevens, B.
10.1101/118646 — neuroscience — Posted on 2017-03-20
454 On the feasibility of mining CD8+ T-cell receptor patterns underlying immunogenic peptide recognition.
De Neuter, N.; Bittremieux, W.; Beirnaert, C.; Cuypers, B.; Mrzic, A.; Moris, P.; Suls, A.; Van Tendeloo, V.; Ogunjimi, B.; Laukens, K.; Meysman, P.
10.1101/118539 — immunology — Posted on 2017-03-20
458 Mercury and water level fluctuations in lakes of northern Minnesota
Larson, J. H.; Maki, R. P.; Christensen, V. G.; Sandheinrich, M. B.; LeDuc, J. F.; Kissane, C.; Knights, B. C.
10.1101/118638 — ecology — Posted on 2017-03-20
464 Invariance of initiation mass and predictability of cell size in Escherichia coli
Si, F.; Li, D.; Cox, S. E.; Sauls, J. T.; Azizi, O.; Sou, C.; Schwartz, A. B.; Erickstad, M. J.; Jun, Y.; Li, X.; Jun, S.
10.1101/081422 — systems biology — Posted on 2017-03-20
465 Genomic inferences of domestication events are corroborated by written records in Brassica rapa
Qi, X.; An, H.; Ragsdale, A.; Hall, T.; Gutenkunst, R. N.; Pires, J. C.; Barker, M. S.
10.1101/118372 — genetics — Posted on 2017-03-20
466 Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene targeted mice
Kanellopoulos, A. H.; Koenig, J.; Huang, H.; Pyrski, M.; Millet, Q.; Lolignier, S.; Morohashi, T.; Gossage, S. J.; Jay, M.; Linley, J.; Baskozos, G.; Kessler, B.; Cox, J. J.; Zufall, F.; Wood, J. N.; Zhao, J.
10.1101/118497 — neuroscience — Posted on 2017-03-20
467 Long-Term Imaging of Cellular Forces with High Precision by Elastic Resonator Interference Stress Microscopy
Kronenberg, N. M.; Liehm, P.; Steude, A.; Knipper, J. A.; Borger, J. G.; Scarcelli, G.; Franze, K.; Powis, S. J.; Gather, M. C.
10.1101/118554 — biophysics — Posted on 2017-03-20
469 Identifiers for the 21st century:How to design, provision, and reuse persistent identifiers to maximize utility and impact of life science data
McMurry, J.; Juty, N.; Blomberg, N.; Burdett, A.; Conlin, T.; Conte, N.; Courtot, M.; Deck, J.; Dumontier, M.; Fellows, D.; Gonzalez-Beltran, A.; Gormanns, P.; Grethe, J.; Hastings, J.; Hermjakob, H.; Heriche, J.-K.; Ison, J.; Jimenez, R.; Jupp, S.; Kunze, J.; Laibe, C.; Le Novere, N.; Malone, J. R.; Martin, M.-J.; McEntyre, J.; Morris, C.; Muilu, J.; Mueller, W.; Rocca-Serra, P.; Sansone, S.-A.; Sariyar, M.; Snoep, J.; Stanford, N. J.; Soiland-Reyes, S.; Swainston, N.; Washington, N.; Williams, A.; Wimalaratne, S.; Winfree, L.; Wolstencroft, K.; Goble, C.; Mungall, C.; Haendel, M.; Parkinson,
10.1101/117812 — bioinformatics — Posted on 2017-03-20
474 Five years investigation of female and male genotypes in Perigord black truffle (Tuber melanosporum Vittad.) revealed contrasted reproduction strategies
De la Varga, H.; Le Tacon, F.; Lagoguet, M.; Todesco, F.; Varga, T.; Miquel, I.; Barry-Etienne, D.; Robin, C.; Halkett, F.; Martin, F.; Murat, C.
10.1101/073650 — microbiology — Posted on 2017-03-20
476 Recent Regulatory Changes Shaped Human Facial and Vocal Anatomy
Gokhman, D.; Agranat-Tamir, L.; Housman, G.; Nissim-Rafinia, M.; Nieves-Colon, M.; Gu, H.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Bontrop, R.; Meissner, A.; Stone, A. C.; Pusey, A. E.; Mjungu, D.; Kandel, L.; Liebergall, M.; Prada, M. E.; Vidal, J. M.; Krause, J.; Yakir, B.; Paabo, S.; Reich, D.; Lalueza-Fox, C.; Marques-Bonet, T.; Meshorer, E.; Carmel, L.
10.1101/106955 — genetics — Posted on 2017-03-20
480 MELODI - Mining Enriched Literature Objects to Derive Intermediates
Elsworth, B. L.; Dawe, K.; Vincent, E. E.; Langdon, R.; Lynch, B. M.; Martin, R. M.; Relton, C.; Higgins, J. P. T.; Gaunt, T. R.
10.1101/118513 — bioinformatics — Posted on 2017-03-20
483 Mean-Field Equations For Neuronal Networks With Arbitrary Degree Distributions
Nykamp, D.; Friedman, D.; Shaker, S.; Shinn, M.; Vella, M.; Compte, A.; Roxin, A.
10.1101/118463 — neuroscience — Posted on 2017-03-20
490 Trabecular Meshwork Failure In A Model Of Pigmentary Glaucoma
Dang, Y.; Waxman, S.; Wang, C.; Loewen, R. T.; Sun, M.; Loewen, N.
10.1101/118448 — cell biology — Posted on 2017-03-20
492 MELODI - Mining Enriched Literature Objects to Derive Intermediates
Elsworth, B. L.; Dawe, K.; Vincent, E. E.; Langdon, R.; Lynch, B. M.; Martin, R. M.; Relton, C.; Higgins, J. P. T.; Gaunt, T.
10.1101/118513 — bioinformatics — Posted on 2017-03-20
493 Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging
Wang, Y.; Woehrstein, J. B.; Donoghue, N.; Dai, M.; Avendano, M. S.; Schackmann, R. C. J.; Wang, S. S.; Tillberg, P. W.; Park, D.; Lapan, S. W.; Boyden, E. S.; Brugge, J. S.; Kaeser, P. S.; Church, G. M.; Agasti, S. S.; Jungmann, R.; Yin, P.
10.1101/112227 — bioengineering — Posted on 2017-03-20
494 3D Mapping Reveals Network-specific Amyloid Progression and Subcortical Susceptibility.
Canter, R. G.; Choi, H.; Wang, J.; Watson, L. A.; Yao, C. G.; Abdurrob, F.; Bousleiman, S. M.; Delalle, I.; Chung, K.; Tsai, L.-H.
10.1101/116244 — neuroscience — Posted on 2017-03-19
498 Genomic basis and evolutionary potential for extreme drought adaptation in Arabidopsis thaliana
Exposito-Alonso, M.; Vasseur, F.; Ding, W.; Wang, G.; Burbano, H. A. A.; Weigel, D.
10.1101/118067 — evolutionary biology — Posted on 2017-03-19
500 Ecological Interactions and the Netflix Problem
Desjardins-Proulx, P.; Laigle, I.; Poisot, T.; Gravel, D.
10.1101/089771 — ecology — Posted on 2017-03-19
501 Population Genomics And The Evolution Of Virulence In The Fungal Pathogen Cryptococcus neoformans
Desjardins, C.; Giamberardino, C.; Sykes, S.; Yu, C.-H.; Tenor, J.; Chen, Y.; Yang, T.; Jones, A.; Sun, S.; Haverkamp, M.; Heitman, J.; Litvintseva, A.; Perfect, J.; Cuomo, C.
10.1101/118323 — genomics — Posted on 2017-03-19
503 P53 is not necessary for DUX4 pathology
Bosnakovski, D.; Toso, E. A.; Recht, O. O.; Cucak, A.; Jain, A. K.; Barton, M. C.; Kyba, M.
10.1101/118315 — genetics — Posted on 2017-03-19
504 Resveratrol Induces Mitochondrial Dysfunction And Decreases Chronological Life Span Of Saccharomyces cerevisiae In A Glucose-Dependent Manner
Ramos-Gomez, M.; Olivares-Marin, I. K.; Canizal-Garcia, M.; Gonzalez-Hernandez, J. C.; Nava, G. M.; Madrigal-Perez, L. A.
10.1101/118307 — biochemistry — Posted on 2017-03-19
505 Sex-associated autosomal DNA methylation differences are wide-spread and stablethroughout childhood
Suderman, M.; Simpkin, A.; Sharp, G. C.; Gaunt, T.; Lyttleton, O.; McArdle, W.; Ring, S.; Davey Smith, G.; Relton, C. L.
10.1101/118265 — epidemiology — Posted on 2017-03-19
507 Identification, Isolation, and Characterization of Human LGR5-positive Colon Adenoma Cells
Dame, M. K.; Attili, D.; McClintock, S. D.; Dedhia, P. H.; Ouilette, P.; Hardt, O.; Chin, A. M.; Xue, X.; Laliberte, J.; Katz, E. L.; Newsome, G. M.; Hill, D.; Miller, A.; Agorku, D.; Altheim, C. H.; Bosio, A.; Simon, B.; Samuelson, L. C.; Stoerker, J. A.; Appelman, H. D.; Varani, J.; Wicha, M. S.; Brenner, D. E.; Shah, Y. M.; Spence, J. R.; Colacino, J. A.
10.1101/118034 — cancer biology — Posted on 2017-03-18
509 A library of structurally homogeneous human N-glycans synthesized from microbial oligosaccharide precursors
Hamilton, B. S.; Wilson, J. D.; Shumakovich, M. A.; Fisher, A. C.; Brooks, J. C.; Pontes, A.; Naran, R.; Heiss, C.; Gao, C.; Kurdish, R.; Heimburg-Molinaro, J.; Azadi, P.; Cummings, R. D.; Merritt, J. H.; DeLisa, M. P.
10.1101/118216 — biochemistry — Posted on 2017-03-18
517 Electrically Conductive Pili from Pilin Genes of Phylogenetically Diverse Microorganisms
Walker, D. J. F.; Adhikari, R. Y.; Holmes, D. E.; Ward, J. E.; Woodard, T. L.; Nevin, K. P.; Lovley, D. R.
10.1101/118059 — microbiology — Posted on 2017-03-18
518 Positive interactions support the formation of complex spatial networks
Losapio, G.; de la Cruz, M.; Escudero, A.; Schmid, B.; Schob, C.
10.1101/118166 — ecology — Posted on 2017-03-18
520 Lysinibacillus fusiformis M5 induces increased complexity in Bacillus subtilis 168 colony biofilms via hypoxanthine
Gallegos Monterrosa, R.; Kankel, S.; Goetze, S.; Barnett, R.; Stallforth, P.; Kovacs, A. T.
10.1101/118125 — microbiology — Posted on 2017-03-18
521 A Genome-wide Survey of Mutations in the Jurkat Cell Line
Gioia, L.; Siddique, A.; Head, S. R.; Salomon, D. R.; Su, A. I.
10.1101/118117 — genomics — Posted on 2017-03-18
522 The genomic footprint of climate adaptation in Chironomus riparius
Oppold, A.-M.; Wieser, A.; Schell, T.; Patel, S.; Schmidt, H.; Hankeln, T.; Feldmeyer, B.; Pfenninger, M.
10.1101/118190 — evolutionary biology — Posted on 2017-03-18
526 Brain connectivity-informed regularization methods for regression
Karas, M.; Brzyski, D.; Dzemidzic, M.; Goni, J.; Kareken, D. A.; Randolph, T. W.; Harezlak, J.
10.1101/117945 — neuroscience — Posted on 2017-03-18
528 Molecular diagnosis of orthopaedic device infection direct from sonication fluid by metagenomic sequencing
Street, T. L.; Sanderson, N. D.; Atkins, B. L.; Brent, A. J.; Cole, K.; Foster, D.; McNally, M. A.; Oakley, S.; Peto, L.; Taylor, A.; Peto, T. E. A.; Crook, D. W.; Eyre, D. W.
10.1101/118026 — microbiology — Posted on 2017-03-18
530 A framework to identify modifier genes in patients with Phelan-McDermid syndrome
Tabet, A.-C.; Rolland, T.; Ducloy, M.; Levy, J.; Buratti, J.; Mathieu, A.; Haye, D.; Perrin, L.; Dupont, C.; Passemard, S.; Capri, Y.; Verloes, A.; Drunat, S.; Keren, B.; Mignot, C.; Marey, I.; Jacquette, A.; Whalen, S.; Pipiras, E.; Benzacken, B.; Chantot-Bastaraud, S.; Afenjar, A.; Heron, D.; Le Caignec, C.; Beneteau, C.; Pichon, O.; Isidor, B.; David, A.; Dupont, J.-M.; Kemeny, S.; Gouas, L.; Vago, P.; Mosca-Boidron, A.-L.; Faivre, L.; Missirian, C.; Philip, N.; Sanlaville, D.; Edery, P.; Satre, V.; Coutton, C.; Devillard, F.; Dieterich, K.; Vuillaume, M.-L.; Rooryck, C.; Lacombe, D.; Pinso
10.1101/117978 — genetics — Posted on 2017-03-18
531 ARIBA: rapid antimicrobial resistance genotyping directly from sequencing reads
Hunt, M.; Mather, A. E.; Sanchez-Buso, L.; Page, A. J.; Parkhill, J.; Keane, J. A.; Harris, S. R.
10.1101/118000 — bioinformatics — Posted on 2017-03-18
533 CNN-based Encoding and Decoding of Visual Object Recognition in Space and Time
Seeliger, K.; Fritsche, M.; Guclu, U.; Schoenmakers, S.; Schoffelen, J.- M.; Bosch, S. E.; van Gerven, M. A. J.
10.1101/118091 — neuroscience — Posted on 2017-03-18
534 Estimating the proportion of disease heritability mediated by gene expression levels
O'Connor, L. J.; Gusev, A.; Liu, X.; Loh, P.-R.; Finucane, H. K.; Price, A. L.
10.1101/118018 — genetics — Posted on 2017-03-18
535 Genomic basis and evolutionary potential for extreme drought adaptation in Arabidopsis thaliana
Exposito-Alonso, M.; Vasseur, F.; Ding, W.; Wang, G.; Burbano, H. A. A.; Weigel, D.
10.1101/118067 — evolutionary biology — Posted on 2017-03-18
536 Single-cell RNA-Sequencing uncovers transcriptional states and fate decisionsin haematopoiesis
Athanasiadis, E. I.; Andres, H.; Botthof, J. G.; Ferreira, L.; Lio, P.; Cvejic, A.
10.1101/117960 — cell biology — Posted on 2017-03-18
537 SQANTI: extensive characterization of long read transcript sequences for quality control in full-length transcriptome identification and quantification
Tardaguila, M.; de la Fuente, L.; Marti, C.; Pereira, C.; del Risco, H.; Ferrell, M.; Mellado, M.; Macchietto, M.; Verheggen, K.; Edelmann, M.; Ezkurdia, I.; Vazquez, J.; Tress, M.; Mortazavi, A.; Martens, L.; Rodriguez-Navarro, S.; Moreno, V.; Conesa, A.
10.1101/118083 — bioinformatics — Posted on 2017-03-18
542 Age-Related Delay in Visual and Auditory Evoked Responses is Mediated by White- and Gray-matter Differences
Price, D.; Tyler, L.; Neto Henriques, R.; Campbell, K.; Williams, N.; Treder, M.; Taylor, J.; Cam-CAN, ; Henson, R.
10.1101/056440 — neuroscience — Posted on 2017-03-17
543 Experience-induced forgetting by WT1 enables learning of sequential tasks.
Mariottini, C.; Munari, L.; Gunzel, E.; Seco, J.; Tzavaras, N.; Hansen, J.; Stern, S.; Gao, V.; Hodes, G.; Russo, S.; Huff, V.; Birtwistle, M.; Alberini, C.; Blitzer, R.; Iyengar, R.
10.1101/101360 — neuroscience — Posted on 2017-03-17
548 Deciphering the combinatorial influence of diet and the microbiota on experimental colitis
Llewellyn, S. R.; Britton, G. J.; Contijoch, E. J.; Mortha, A.; Colombel, J.-F.; Grinspan, A.; Clemente, J. C.; Merad, M.; Faith, J. J.
10.1101/117929 — microbiology — Posted on 2017-03-17
549 Variation Of The Meiotic Recombination Landscape And Properties Over A Broad Evolutionary Distance In Yeasts
Brion, C.; Legrand, S.; Peter, J.; Caradec, C.; Pflieger, D.; Hou, J.; Friedrich, A.; Llorente, B.; Schacherer, J.
10.1101/117895 — genomics — Posted on 2017-03-17
556 Increased pericarp cell length underlies a major QTL for grain weight in hexaploid wheat
Brinton, J.; Simmonds, J.; Minter, F.; Leverington-Waite, M.; Snape, J.; Uauy, C.
10.1101/117937 — plant biology — Posted on 2017-03-17
557 Genome-Wide Analysis Of 113,968 Individuals In UK Biobank Identifies Four Loci Associated With Mood Instability.
Ward, J.; Strawbridge, R.; Graham, N.; Bailey, M.; Freguson, A.; Lyall, D.; Cullen, B.; Pidegon, L.; Cavanagh, J.; Mackay, D.; Pell, J.; O'Donovan, M.; Escott-Price, V.; Smith, D. J.
10.1101/117796 — neuroscience — Posted on 2017-03-17
559 Comprehensive Pathway Analyses Of Schizophrenia Risk Loci Point To Dysfunctional Postsynaptic Signaling
Schijven, D.; Kofink, D.; Tragante, V.; Verkerke, M.; Pulit, S. L.; Kahn, R. S.; Veldink, J. H.; Vinkers, C. H.; Boks, M. P.; Luykx, J. J.
10.1101/117481 — genetics — Posted on 2017-03-17
561 Validation Of A Novel Molecular Host Response Assay To Diagnose Infection In Hospitalized Patients Admitted To The ICU With Acute Respiratory Failure
Koster-Brouwer, M.; Verboom, D.; Scicluna, B.; van de Groep, K.; Frencken, J.; Janssen, D.; Schuurman, R.; Schultz, M.; van der Poll, T.; Bonten, M.; Cremer, O.
10.1101/117853 — epidemiology — Posted on 2017-03-17
562 Comparison Of Multi-locus Sequence Typing Software For Next Generation Sequencing Data
Page, A. J.; Alikhan, N.-F.; Carleton, H. A.; Seemann, T.; Keane, J. A.; Katz, L. S.
10.1101/117770 — bioinformatics — Posted on 2017-03-17
563 Probabilistic Recovery Of Cryptic Haplotypes From Metagenomic Data
Nicholls, S. M.; Aubrey, W.; de Grave, K.; Schietgat, L.; Creevey, C. J.; Clare, A.
10.1101/117838 — bioinformatics — Posted on 2017-03-17
564 CpG traffic lights are markers of regulatory regions in humans
Khamis, A. M.; Lioznova, A. V.; Artemov, A. V.; Ramensky, V.; Bajic, V. B.; Medvedeva, Y. A.
10.1101/095968 — bioinformatics — Posted on 2017-03-17
568 Adaptive pathways of coral populations on the Great Barrier Reef
Matz, M. V.; Treml, E. A.; Aglyamova, G. V.; van Oppen, M. J. H.; Bay, L. K.
10.1101/114173 — evolutionary biology — Posted on 2017-03-17
569 Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia
Nematbakhsh, A.; Sun, W.; Brodskiy, P. A.; Amiri, A.; Narciso, C.; Xu, Z.; Zartman, J. J.; Alber, M. S.
10.1101/037820 — biophysics — Posted on 2017-03-17
570 Focus: The interface between data collection and data processing in cryo-EM
Biyani, N.; Righetto, R. D.; McLeod, R.; Caujolle-Bert, D.; Castano-Diez, D.; Goldie, K. N.; Stahlberg, H.
10.1101/105452 — biophysics — Posted on 2017-03-17
573 The Drosophila Embryo at Single Cell Transcriptome Resolution
Karaiskos, N.; Wahle, P.; Alles, J.; Boltengagen, A.; Ayoub, S.; Kipar, C.; Kocks, C.; Rajewsky, N.; Zinzen, R. P.
10.1101/117382 — genomics — Posted on 2017-03-17
575 Autonomous Bird Sound Recording Outperforms Direct Human Observation: Synthesis And New Evidence
Darras, K. F. A.; Batary, P.; Furnas, B.; Fitriawan, I.; Mulyani, Y.; Tscharntke, T.
10.1101/117119 — ecology — Posted on 2017-03-17
587 Guiding the design of bacterial signaling interactions using a coevolutionary landscape
Cheng, R. R.; Haglund, E.; Tiee, N.; Morcos, F.; Levine, H.; Adams, J. A.; Jennings, P. A.; Onuchic, J. N.
10.1101/116947 — bioinformatics — Posted on 2017-03-16
588 Familiarity Facilitates Feature-based Face Processing
Visconti di Oleggio Castello, M.; Wheeler, K. G.; Cipolli, C.; Gobbini, M. I.
10.1101/058537 — neuroscience — Posted on 2017-03-16
592 Intracellular production of hydrogels and synthetic RNA granules by multivalent enhancers
Nakamura, H.; Lee, A. A.; Afshar, A. S.; Watanabe, S.; Rho, E.; Razavi, S.; Suarez, A.; Lin, Y.-C.; Tanigawa, M.; Huang, B.; DeRose, R.; Bobb, D.; Hong, W.; Gabelli, S. B.; Goutsias, J.; Inoue, T.
10.1101/117572 — synthetic biology — Posted on 2017-03-16
593 Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase
Asquith, C. R. M.; Laitinen, T.; Bennett, J. M.; Godoi, P. H.; Tizzard, G. J.; Elkins, J. M.; Willson, T. M.; Zuercher, W. J.
10.1101/117630 — pharmacology and toxicology — Posted on 2017-03-16
595 Adult sex ratio bias in snowy plovers is driven by sex-specific early survival: implications for mating systems and population growth
Eberhart-Phillips, L. J.; Kuepper, C.; Miller, T. E. X.; Cruz-Lopez, M.; Maher, K. H.; dos Remedios, N.; Stoffel, M. A.; Hoffman, J. I.; Krueger, O.; Szekely, T.
10.1101/117580 — ecology — Posted on 2017-03-16
599 Harmonization Of Multi-Site Diffusion Tensor Imaging Data
Fortin, J.-P.; Parker, D.; Tunc, B.; Watanabe, T.; Elliott, M. A.; Ruparel, K.; Roalf, D. R.; Satterthwaite, T. D.; Gur, R. C.; Gur, R. E.; Schultz, R. T.; Verma, R.; Shinohara, R. T.
10.1101/116541 — neuroscience — Posted on 2017-03-16
602 HUGIn: Hi-C Unifying Genomic Interrogator
Martin, J. S.; Xu, Z.; Reiner, A. P.; Mohlke, K. L.; Sullivan, P.; Ren, B.; Hu, M.; Li, Y.
10.1101/117531 — genetics — Posted on 2017-03-16
604 The Golgi matrix protein giantin is required for normal cilia function in zebrafish
Bergen, D. J.; Stevenson, N. L.; Skinner, R. J.; Stephens, D. J.; Hammond, C. L.
10.1101/117507 — developmental biology — Posted on 2017-03-16
605 Gene nucleotide composition accurately predicts expression and is linked to topological chromatin domains
Bessiere, C.; Taha, M.; Petitprez, F.; Vandel, J.; Marin, J.-M.; Brehelin, L.; Lebre, S.; Lecellier, C.-H.
10.1101/117499 — bioinformatics — Posted on 2017-03-16
607 Drug Target Ontology to Classify and Integrate Drug Discovery Data
Lin, Y.; Mehta, S.; McGinty, H. K.; Turner, J. P.; Vidovic, D.; Forlin, M.; Koleti, A.; Nguyen, D.-T.; Jensen, L. J.; Guha, R.; Mathias, S. L.; Ursu, O.; Stathias, V.; Duan, J.; Nabizadeh, N.; Chung, C.; Mader, C.; Visser, U.; Yang, J. J.; Bologa, C. G.; Oprea, T.; Schurer, S. C.
10.1101/117564 — bioinformatics — Posted on 2017-03-16
612 A toolbox of immunoprecipitation-grade monoclonal antibodies against human transcription factors.
Venkataraman, A.; Yang, K.; Irrizary, J.; Mackiewicz, M.; Mita, P.; Kuang, Z.; Xue, L.; Ghosh, D.; Liu, S.; Ramos, P.; Hu, S.; Bayron, D.; Keegan, S.; Saul, R.; Colantonio, S.; Zhang, H.; Pauli Behn, F.; Song, G.; Albino, E.; Asencio, L.; Ramos, L.; Lugo, L.; Morell, G.; Rivera, J.; Ruiz, K.; Almodovar, R.; Nazario, L.; Murphy, K.; Vargas, I.; Rivera-Pacheco, Z.; Rosa, C.; Vargas, M.; McDade, J.; Clark, B. S.; Yoo, S.; Khambadkone, S. G.; de Melo, J.; Stevanovic, M.; Jiang, L.; Li, Y.; Yap, W. Y.; Jones, B.; Tandon, A.; Campbell, E.; Anderson, S.; Myers, R. M.; Boeke, J. D.; Fenyo, D.; Whitele
10.1101/116442 — biochemistry — Posted on 2017-03-16
613 Activation of the hypothalamic feeding centre upon visual prey detection
Muto, A.; Lal, P.; Ailani, D.; Abe, G.; Itoh, M.; Kawakami, K.
10.1101/078527 — neuroscience — Posted on 2017-03-16
616 Assessing the stability of polio eradication after the withdrawal of oral polio vaccine
Famulare, M.; Selinger, C.; McCarthy, K. A.; Chabot-Couture, G.; Eckhoff, P. A.
10.1101/084012 — epidemiology — Posted on 2017-03-16
618 Environmental modification via a quorum sensing molecule influences the social landscape of siderophore production
Popat, R.; Harrison, F.; da Silva, A. C.; Easton, S. A. S.; McNally, L.; Williams, P.; Diggle, S. P.
10.1101/053918 — microbiology — Posted on 2017-03-16
619 Characterizing and predicting cyanobacterial blooms in an 8-year amplicon sequencing time-course
Tromas, N.; Fortin, N.; Bedrani, L.; Terrat, Y.; Cardoso, P.; Bird, D.; Greer, C. W.; Shapiro, B. J.
10.1101/058289 — microbiology — Posted on 2017-03-16
621 HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution
Kamath, G. M.; Shomorony, I.; Xia, F.; Courtade, T. A.; Tse, D. N.
10.1101/062117 — bioinformatics — Posted on 2017-03-16
623 Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens
Hart, T.; Tong, A.; Chan, K.; van Leeuwen, J.; Seetharaman, A.; Aregger, M.; Chandrashekhar, M.; Hustedt, N.; Seth, S.; Noonan, A.; Habsid, A.; Sizova, O.; Nedyalkova, L.; Climie, R.; Lawson, K.; Sartori, M. A.; Alibai, S.; Tieu, D.; Masud, S.; Mero, P.; Weiss, A.; Brown, K. R.; Ušaj, M.; Billmann, M.; Rahman, M.; Costanzo, M.; Myers, C. L.; Andrews, B.; Boone, C.; Durocher, D.; Moffat, J.
10.1101/117341 — systems biology — Posted on 2017-03-16
624 Transcription Through The Eye Of A Needle: Daily And Annual Cycles Of Gene Expression Variation In Douglas-Fir Needles
Cronn, R.; Dolan, P. C.; Jogdeo, S.; Wegrzyn, J. L.; Neale, D. B.; St. Clair, J. B.; Denver, D. R.
10.1101/117374 — plant biology — Posted on 2017-03-16
625 Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression
Kar, G.; Kim, J. K.; Kolodziejczyk, A. A.; Natarajan, K. N.; Triglia, E. T.; Mifsud, B.; Elderkin, S.; Marioni, J. C.; Pombo, A.; Teichmann, S. A.
10.1101/117267 — genomics — Posted on 2017-03-16
627 Evolution and clinical impact of genetic epistasis within EGFR-mutant lung cancers
Blakely, C. M.; Watkins, T. B. K.; Wu, W.; Gini, B.; Chabon, J. J.; McCoach, C. E.; McGranahan, N.; Wilson, G. A.; Birkbak, N. J.; Olivas, V.; Rotow, J.; Maynard, A.; Wang, V.; Gubens, M.; Banks, K.; Lanman, R.; Caulin, A.; St. John, J.; Cordero, A.; Giannikopoulos, P.; Mack, P.; Gandara, D.; Husain, H.; Doebele, R.; Riess, J.; Diehn, M.; Swanton, C.; Bivona, T. G.
10.1101/117291 — cancer biology — Posted on 2017-03-16
628 cAMP-Independent Control Of Twitching Motility In Pseudomonas aeruginosa
Buensuceso, R. N. C.; Daniel-Ivad, M.; Kilmury, S. L. N.; Harvey, H.; Howell, P. L.; Burrows, L. L.
10.1101/116954 — microbiology — Posted on 2017-03-15
631 A marker-free co-selection strategy for high efficiency human genome engineering
Agudelo, D.; Bozoyan, L.; Duringer, A.; Huard, C. C.; Carter, S.; Loehr, J.; Synodinou, D.; Drouin, M.; Salsman, J.; Dellaire, G.; Laganiere, J.; Doyon, Y.
10.1101/116251 — molecular biology — Posted on 2017-03-15
633 Mapping Autosomal Recessive Intellectual Disability: Combined Microarray and Exome Sequencing Identifies 26 Novel Candidate Genes in 192 Consanguineous Families
Harripaul, R.; Vasli, N.; Mikhailov, A.; Rafiq, M. A.; Mittal, K.; Windpassinger, C.; Sheikh, T.; Noor, A.; Mahmood, H.; Downey, S.; Johnson, M.; Vleuten, K.; Bell, L.; Ilyas, M.; Khan, F. S.; Khan, V.; Moradi, M.; Ayaz, M.; Naeem, F.; Heidari, A.; Ahmed, I.; Ghadami, S.; Agha, Z.; Zeinali, S.; Qamar, R.; Mozhdehipanah, H.; John, P.; Mir, A.; Ansar, M.; French, L.; Ayub, M.; Vincent, J. B.
10.1101/092346 — genetics — Posted on 2017-03-15
634 Genotoxin-induced transcriptional repression regulates selective protein aggregation
Mathew, V.; Tam, A. S.; Milbury, K. L.; Hofmann, A. K.; Hughes, C. S.; Morin, G. B.; Loewen, C. J.; Stirling, P.
10.1101/116822 — cell biology — Posted on 2017-03-15
638 Molecular Basis Underlying Male Sterility In bHLH142 Overexpressing Rice
Ko, S.-S.; Li, M.-J.; Lin, Y.-J.; Hsing, H.-X.; Yang, T.-T.; Chen, T.-K.; Jhong, C.-M.; Ku, M. S.-B.
10.1101/116996 — molecular biology — Posted on 2017-03-15
639 cAMP-Independent Control Of Twitching Motility In Pseudomonas aeruginosa
Buensuceso, R. N. C.; Daniel-Ivad, M.; Kilmury, S. L. N.; Harvey, H.; Howell, P. L.; Burrows, L. L.
10.1101/116954 — microbiology — Posted on 2017-03-15
641 Heritable Small RNAs Regulate Nematode Benzimidazole Resistance
Zamanian, M.; Cook, D. E.; Lee, D.; Lee, J.; Andersen, E.
10.1101/116970 — genetics — Posted on 2017-03-15
644 Inhibitory Engrams In Perception And Memory.
Barron, H.; Vogels, T. P.; Behrens, T. E.; Ramaswami, M.
10.1101/117085 — neuroscience — Posted on 2017-03-15
651 Reconstructing Promoter Activity From Lux Bioluminescent Reporters
Iqbal, M.; Doherty, N.; Page, A. M. L.; Qazi, S. N. A.; Ajmera, I.; Lund, P. A.; Kypraios, T.; Scott, D. J.; Hill, P. J.; Stekel, D. J.
10.1101/117093 — bioinformatics — Posted on 2017-03-15
654 powsim: Power analysis for bulk and single cell RNA-seq experiments
Vieth, B.; Ziegenhain, C.; Parekh, S.; Enard, W.; Hellmann, I.
10.1101/117150 — bioinformatics — Posted on 2017-03-15
659 A toolbox of immunoprecipitation-grade monoclonal antibodies against human transcription factors.
Venkataraman, A.; Yang, K.; Irrizary, J.; Mackiewicz, M.; Mita, P.; Kuang, Z.; Xue, L.; Ghosh, D.; Liu, S.; Ramos, P.; Hu, S.; Bayron, D.; Keegan, S.; Saul, R.; Colantonio, S.; Zhang, H.; Pauli Behn, F.; Song, G.; Albino, E.; Asencio, L.; Ramos, L.; Lugo, L.; Morell, G.; Rivera, J.; Ruiz, K.; Almodovar, R.; Nazario, L.; Murphy, K.; Vargas, I.; Rivera-Pacheco, Z.; Rosa, C.; Vargas, M.; McDade, J.; Clark, B.; Yoo, S.; Khambadkone, S.; de Melo, J.; Stevanovic, M.; Jiang, L.; Li, Y.; Yap, W.; Jones, B.; Tandon, A.; Campbell, E.; Anderson, S.; Myers, R.; Boeke, J.; Fenyo, D.; Whiteley, G.; Bader, J
10.1101/116442 — biochemistry — Posted on 2017-03-15
660 Harmonization Of Multi-Site Diffusion Tensor Imaging Data
Fortin, J.-P.; Parker, D.; Tunc, B.; Watanabe, T.; Elliott, M. A.; Ruparel, K.; Roalf, D. R.; Satterthwaite, T. D.; Gur, R. C.; Gur, R. E.; Schultz, R. T.; Verma, R.; Shinohara, R. T.
10.1101/116541 — neuroscience — Posted on 2017-03-15
661 Ancient European dog genomes reveal continuity since the early Neolithic
Botigue, L.; Song, S.; Scheu, A.; Gopalan, S.; Pendleton, A.; Oetjens, M.; Taravella, A.; Seregely, T.; Zeeb-Lanz, A.; Arbogast, R.-M.; Bobo, D.; Daly, K.; Unterlander, M.; Burger, J.; Kidd, J.; Veeramah, K. R.
10.1101/068189 — genomics — Posted on 2017-03-15
662 Destructive Disinfection Of Infected Brood Prevents Systemic Disease Spread In Ant Colonies
Pull, C. D.; Ugelvig, L. V.; Wiesenhofer, F.; Tragust, S.; Schmitt, T.; Brown, M. J.; Cremer, S.
10.1101/116657 — evolutionary biology — Posted on 2017-03-15
666 Stacks off tracks: A role for the golgin AtCASP in plant endoplasmic reticulum - Golgi apparatus tethering
Osterrieder, A.; Hawes, C.; Sparkes, I. A.; Botchway, S.; Ward, A.; Ketelaar, T.; De Ruijter, N.
10.1101/115840 — plant biology — Posted on 2017-03-14
669 Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch
Papadopoulos, D. K.; Skouloudaki, K.; Engstrom, Y.; Terenius, L.; Rigler, R.; Vukojevic, V.; Tomancak, P.
10.1101/115220 — genetics — Posted on 2017-03-14
671 Identifying genetic variants that affect viability in large cohorts
Mostafavi, H.; Berisa, T.; Day, F.; Perry, J.; Przeworski, M.; Pickrell, J. K.
10.1101/085969 — evolutionary biology — Posted on 2017-03-14
673 On the genetic and environmental reasons why intelligence correlates with criminal victimization
Boutwell, B.; Connolly, E.; Barbaro, N.; Shackelford, T.; Petkovsek, M.; Beaver, K.
10.1101/113712 — epidemiology — Posted on 2017-03-14
675 A microbially derived tyrosine sulfated peptide mimics a plant peptide hormone
Pruitt, R. N.; Joe, A.; Zhang, W.; Feng, W.; Stewart, V.; Schwessinger, B.; Dinneny, J. R.; Ronald, P. C.
10.1101/116897 — plant biology — Posted on 2017-03-14
678 Reconciling Conflicting Models for Global Control of Cell-Cycle Transcription
Cho, C.-Y.; Motta, F. C.; Kelliher, C. M.; Deckard, A.; Haase, S. B.
10.1101/116798 — cell biology — Posted on 2017-03-14
680 A toolbox of immunoprecipitation-grade monoclonal antibodies against human transcription factors.
Venkataraman, A.; Yang, K.; Irrizary, J.; Mackiewicz, M.; Mita, P.; Kuang, Z.; Xue, L.; Ghosh, D.; Liu, S.; Ramos, P.; Hu, S.; Bayron, D.; Keegan, S.; Saul, R.; Colantonio, S.; Zhang, H.; Pauli Behn, F.; Song, G.; Albino, E.; Asencio, L.; Ramos, L.; Lugo, L.; Morell, G.; Rivera, J.; Ruiz, K.; Almodovar, R.; Nazario, L.; Murphy, K.; Vargas, I.; Rivera-Pacheco, Z.; Rosa, C.; Vargas, M.; McDade, J.; Clark, B.; Yoo, S.; Khambadkone, S.; de Melo, J.; Stevanovic, M.; Jiang, L.; Li, Y.; Yap, W.; Jones, B.; Tandon, A.; Campbell, E.; Anderson, S.; Myers, R.; Boeke, J.; Fenyo, D.; Whiteley, G.; Bader, J
10.1101/116442 — biochemistry — Posted on 2017-03-14
681 DLPFC Transcriptome Defines Two Molecular Subtypes of Schizophrenia
Rhodes, C. H.; Bowen, E. F. W.; Lee, C. I.; Burgess, J. L.; Granger, R.
10.1101/116699 — neuroscience — Posted on 2017-03-14
682 Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics
Breuer, R.; Mattheisen, M.; Frank, J.; Krumm, B.; Treutlein, J.; Kassem, L.; Strohmaier, J.; Herms, S.; Muhleisen, T. W.; Degenhardt, F.; Cichon, S.; Nothen, M.; Karypis, G.; Bipolar Disorder Genetics (BiGS) Consortium, ; McMahon, F. J.; Rietschel, M.; Schulze, T. G.
10.1101/116624 — genomics — Posted on 2017-03-14
683 Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).
Clarke, T.-K.; Adams, M. J.; Davies, G.; Howard, D. M.; Hall, L. S.; Padmanabhan, S.; Murray, A. D.; Smith, B. H.; Campbell, A.; Hayward, C.; Porteous, D. J.; Deary, I. J.; McIntosh, A. M.
10.1101/116707 — genetics — Posted on 2017-03-14
685 Habitat Fragmentation Causes Coevolutionary Burning Spots
De Kort, H.; Baguette, M.; Prunier, J.; Tessier, M.; Monsimet, J.; Turlure, C.; Stevens, V.
10.1101/116293 — evolutionary biology — Posted on 2017-03-14
686 Evolution of Animal Neural Systems
Liebeskind, B. J.; Hofmann, H. A.; Hillis, D. M.; Zakon, H. H.
10.1101/116715 — evolutionary biology — Posted on 2017-03-14
688 Reconstructing regulatory pathways by systematically mapping protein localization interdependency networks
Dodgson, J.; Chessel, A.; Vaggi, F.; Giordan, M.; Yamamoto, M.; Arai, K.; Madrid, M.; Geymonat, M.; Abenza, J. F.; Cansado, J.; Sato, M.; Csikasz-Nagy, A.; Carazo-Salas, R. E.
10.1101/116749 — cell biology — Posted on 2017-03-14
689 Genome Graphs and the Evolution of Genome Inference
Paten, B.; Novak, A. M.; Eizenga, J. M.; Garrison, E.
10.1101/101816 — bioinformatics — Posted on 2017-03-14
691 Differential Expression Analysis for RNAseq using Poisson Mixed Models
Sun, S.; Hood, M.; Scott, L.; Peng, Q.; Mukherjee, S.; Tung, J.; Zhou, X.
10.1101/073403 — genomics — Posted on 2017-03-14
694 Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish
van Veen, M.; van Pelt, J.; Mans, L. A.; Moolenaar, W. H.; Haramis, A.-P.
10.1101/108779 — developmental biology — Posted on 2017-03-14
695 Stability and function of a putative microtubule organizing center in the human parasite Toxoplasma gondii
Leung, J. M.; He, Y.; Zhang, F.; Hwang, Y.-C.; Nagayasu, E.; Liu, J.; Murray, J. M.; Hu, K.
10.1101/099267 — cell biology — Posted on 2017-03-14
696 SCFSlmb recognizes a conserved degron within the survival motor neuron (SMN) self-interaction domain to mediate ubiquitylation of SMN and SMNΔ7 isoforms
Gray, K. M.; Kaifer, K. A.; Baillat, D.; Wen, Y.; Bonacci, T. R.; Ebert, A. D.; Raimer, A. C.; Spring, A. M.; Glascock, J. J.; ten Have, S.; Emanuele, M. J.; Lamond, A. I.; Wagner, E. J.; Lorson, C. L.; Matera, A. G.
10.1101/078337 — biochemistry — Posted on 2017-03-14
698 The Molecular Link Between Auxin And ROS-Mediated Polar Growth
Mangano, S.; Denita-Juarez, S. P.; Choi, H.-S.; Marzol, E.; Hwang, Y.; Ranocha, P.; Velasquez, S. M.; Muschietti, J. P.; Dunand, C.; Cho, H.-T.; Estevez, J. M.
10.1101/116517 — plant biology — Posted on 2017-03-14
701 Tracking electron uptake from a cathode into Shewanella cells: implications for generating maintenance energy from solid substrates.
Rowe, A. R.; Rajeev, P.; Jain, A.; Pirbadian, S.; Okamotao, A.; Gralnick, J. A.; El-Naggar, M. Y.; Nealson, K.
10.1101/116475 — microbiology — Posted on 2017-03-14
702 The Protective Association Of Endogenous Immunoglobulins Against Sepsis Mortality Is Restricted To Patients With Moderate Organ Failure.
Martin-Loeches, I.; Muriel-Bombin, A.; Ferrer, R.; Artigas, A.; Sole-Violan, J.; Lorente, L.; Andaluz-Ojeda, D.; Prina-Mello, A.; Herran-Monge, R.; Suberviola, B.; Rodriguez-Fernandez, A.; Merino, P.; Loza, A. M.; Garcia-Olivares, P.; Anton, E.; Tamayo, E.; Trapiello, W.; Blanco, J.; Bermejo-Martin, J. F.; GRECIA Group,
10.1101/116665 — immunology — Posted on 2017-03-14
703 Severe infections emerge from the microbiome by adaptive evolution
Young, B. C.; Wu, C.-H.; Gordon, N. C.; Cole, K.; Price, J. R.; Liu, E.; Sheppard, A.; Perera, S.; Charlesworth, J.; Golubchik, T.; Iqbal, Z.; Bowden, R.; Massey, R.; Paul, J.; Crook, D. W.; Peto, T. E.; Walker, A. S.; Llewelyn, M.; Wyllie, D. H.; Wilson, D.
10.1101/116681 — genomics — Posted on 2017-03-14
704 Maternal and fetal genetic contribution to gestational weight gain
Warrington, N.; Richmond, R.; Fenstra, B.; Myhre, R.; Gaillard, R.; Paternoster, L.; Wang, C.; Beaumont, R.; Das, S.; Murcia, M.; Barton, S.; Espinosa, A.; Thiering, E.; Atalay, M.; Pitkinen, N.; Ntalla, I.; Jonsson, A.; Freathy, R.; Karhunen, V.; Tiesler, C.; Allard, C.; Crawford, A.; Ring, S.; Melbye, M.; Magnus, P.; Rivadeneira, F.; Skott, L.; Hansen, T.; Marsh, J.; Guxens, M.; Holloway, J.; Grallert, H.; Jaddoe, V.; Lowe, W.; Roumeliotaki, T.; Hattersley, A.; Lindi, V.; Pahkala, K.; Panoutsopoulou, K.; Standl, M.; Flexeder, C.; Bouchard, L.; Nohr, E. A.; Santa Marina, L.; Kogevinas, M.; Ni
10.1101/116434 — genetics — Posted on 2017-03-14
709 Dynamic response to initial stage blindness in visual system development
Long, E.; Zhang, X.; Liu, Z.; Wu, X.; Tan, X.; Lin, D.; Cao, Q.; Chen, J.; Lin, Z.; Wang, D.; Li, X.; Li, J.; Wang, J.; Li, W.; Lin, H.; Chen, W.; Liu, Y.
10.1101/116590 — developmental biology — Posted on 2017-03-14
710 Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration
Zaritsky, A. M.; Tseng, Y.-Y.; Rabadan, A. M.; Krishna, S.; Overholtzer, M.; Danuser, G.; Hall, A.
10.1101/076125 — cell biology — Posted on 2017-03-14
711 Gene-centric constraint of metabolic models
Fyson, N.; Kim, M. K.; Lun, D.; Colijn, C.
10.1101/116558 — biochemistry — Posted on 2017-03-14
713 On the distribution and function of synaptic clusters
Caze, R. D.; Foust, A. J.; Clopath, C.; Schultz, S. R.
10.1101/029330 — neuroscience — Posted on 2017-03-14
718 Combining inferred regulatory and reconstructed metabolic networks enhances phenotype prediction in yeast
Wang, Z.; Danziger, S. A.; Heavner, B. D.; Ma, S.; Smith, J. J.; Li, S.; Herricks, T.; Simeonidis, E.; Baliga, N. S.; Aitchison, J. D.; Price, N. D.
10.1101/087148 — systems biology — Posted on 2017-03-13
722 A global perspective of codon usage
Khomtchouk, B.; Wahlestedt, C.; Nonner, W.
10.1101/076679 — genetics — Posted on 2017-03-13
723 Distinct Blood DNA Methylation Profiles In Subtypes Of Orofacial Cleft
Sharp, G. C.; Ho, K.; Davies, A.; Stergiakouli, E.; Humphries, K.; McArdle, W.; Sandy, J.; Davey Smith, G.; Lewis, S. J.; Relton, C. L.
10.1101/113266 — epidemiology — Posted on 2017-03-13
724 Deletion of the short N-terminal extension in OCP reveals the main site for the FRP binding
Sluchanko, N. N.; Slonimskiy, Y. B.; Moldenhauer, M.; Friedrich, T.; Maksimov, E. G.
10.1101/116491 — biophysics — Posted on 2017-03-13
726 Distinct Blood DNA Methylation Profiles In Subtypes Of Orofacial Cleft
Sharp, G. C.; Ho, K.; Davies, A.; Stergiakouli, E.; Humphries, K.; McArdle, W.; Sandy, J.; Davey Smith, G.; Lewis, S. J.; Relton, C. L.
10.1101/113266 — epidemiology — Posted on 2017-03-13
729 Inferring Within-Host Bottleneck Size: A Bayesian Approach
Dybowski, R.; Restif, O.; Price, D. J.; Mastroeni, P.
10.1101/116194 — microbiology — Posted on 2017-03-13
730 How well do RNA-Seq differential gene expression tools perform in a eukaryote with a complex transcriptome?
Froussios, K.; Schurch, N. J.; Mackinnon, K.; Gierlinski, M.; Duc, C.; Simpson, G. G.; Barton, G. J.
10.1101/090753 — genomics — Posted on 2017-03-13
731 De novo mutations in regulatory elements cause neurodevelopmental disorders
Short, P. J.; McRae, J. F.; Gallone, G.; Sifrim, A.; Won, H.; Geschwind, D. H.; Wright, C. F.; Firth, H. V.; FitzPatrick, D. R.; Barrett, J. C.; Hurles, M. E.
10.1101/112896 — genetics — Posted on 2017-03-13
732 Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
Kim-Hellmuth, S.; Bechheim, M.; Puetz, B.; Mohammadi, P.; Nedelec, Y.; Giangreco, N.; Becker, J.; Kaiser, V.; Fricker, N.; Beier, E.; Boor, P.; Castel, S.; Noethen, M. M.; Barreiro, L. B.; Pickrell, J. K.; Mueller-Myhsok, B.; Lappalainen, T.; Schumacher, J.; Hornung, V.
10.1101/116376 — genetics — Posted on 2017-03-13
733 Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance
Chen, Y.; Dela Cruz, F.; Sandhu, R.; Kung, A.; Mundi, P.; Deasy, J.; Tannenbaum, A.
10.1101/116384 — cancer biology — Posted on 2017-03-13
737 Ambient temperature and genotype differentially affect developmental and phenotypic plasticity in Arabidopsis thaliana
Ibanez, C.; Poeschl, Y.; Peterson, T.; Bellstaedt, J.; Denk, K.; Gogol-Doering, A.; Quint, M.; Delker, C.
10.1101/017285 — plant biology — Posted on 2017-03-13
738 Recent Regulatory Changes Shaped Human Facial and Vocal Anatomy
Gokhman, D.; Agranat-Tamir, L.; Housman, G.; Nissim-Rafinia, M.; Nieves-Colon, M.; Gu, H.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Bontrop, R.; Meissner, A.; Stone, A. C.; Pusey, A. E.; Mjungu, D.; Kandel, L.; Liebergall, M.; Prada, M. E.; Vidal, J. M.; Krause, J.; Yakir, B.; Paabo, S.; Reich, D.; Lalueza-Fox, C.; Marques-Bonet, T.; Meshorer, E.; Carmel, L.
10.1101/106955 — paleontology — Posted on 2017-03-13
739 Task-specific, dimension-based attentional shaping of motion processing in area MT
Schledde, B.; Galashan, F. O.; Przybyla, M.; Kreiter, A. K.; Wegener, D.
10.1101/058693 — neuroscience — Posted on 2017-03-13
744 Structural basis for EarP-mediated arginine glycosylation of translation elongation factor EF-P
Krafczyk, R.; Macosek, J.; Gast, D.; Wunder, S.; Jagtap, P. K. A.; Mitra, P.; Jha, A. K.; Rohr, J.; Hoffmann-Roeder, A.; Jung, K.; Hennig, J.; Lassak, J.
10.1101/116038 — biochemistry — Posted on 2017-03-13
746 Feeding Schedule And Proteolysis Regulate Autophagic Clearance Of Mutant Huntingtin
Ehrnhoefer, D. E.; Martin, D. D.; Qiu, X.; Ladha, S.; Caron, N. S.; Skotte, N. H.; Nguyen, Y. T.; Engemann, S.; Franciosi, S.; Hayden, M. R.
10.1101/116178 — neuroscience — Posted on 2017-03-13
747 3D Mapping Reveals Network-specific Amyloid Progression and Subcortical Susceptibility.
Canter, R. G.; Choi, H.; Wang, J.; Watson, L. A.; Yao, C. G.; Abdurrob, F.; Bousleiman, S. M.; Delalle, I.; Chung, K.; Tsai, L.-H.
10.1101/116244 — neuroscience — Posted on 2017-03-13
748 Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in ciliate Tetrahymena
Iwamoto, M.; Osakada, H.; Mori, C.; Fukuda, Y.; Nagao, K.; Obuse, C.; Hiraoka, Y.; Haraguchi, T.
10.1101/116277 — cell biology — Posted on 2017-03-13
749 Sinusoidal Voltage Protocols For Rapid Characterization Of Ion Channel Kinetics
Beattie, K. A.; Hill, A. P.; Bardenet, R.; Cui, Y.; Vandenberg, J. I.; Gavaghan, D. J.; de Boer, T. P.; Mirams, G. R.
10.1101/100677 — biophysics — Posted on 2017-03-13
753 Stochastic Protein Labeling Enables Long-term Single Molecule Observation In Vivo
Liu, H.; Dong, P.; Ioannou, M. S.; Li, L.; Shea, J.; Pasolli, A.; Grimm, J.; Rivlin, P.; Lavis, L. D.; Koyama, M.; Liu, Z.
10.1101/116186 — biophysics — Posted on 2017-03-13
754 LARGE-SCALE GENOMIC REORGANIZATIONS OF TOPOLOGICAL DOMAINS (TADs) AT THE HoxD LOCUS
Fabre, P. J.; Leleu, M.; Mormann, B. H.; Delisle, L.; Noordermeer, D.; Beccari, L.; Duboule, D.
10.1101/116152 — genomics — Posted on 2017-03-12
757 Intrinsic Hippocampal-Caudate Interaction Correlates with Human Navigation
Kong, X.-Z.; Pu, Y.; Wang, X.; Xu, S.; Hao, X.; Zhen, Z.; Liu, J.
10.1101/116129 — neuroscience — Posted on 2017-03-12
758 T-bet+ CD11c+ B Cells Are Critical For Anti-Chromatin IgG Production In The Development Of Lupus
Liu, Y.; Zhou, S.; Qian, J.; Wang, Y.; Yu, X.; Dai, D.; Dai, M.; Wu, L.; Liao, Z.; Xue, Z.; Wang, J.; Hou, G.; Ma, J.; Harley, J. B.; Tang, Y.; Shen, N.
10.1101/116145 — immunology — Posted on 2017-03-12
759 A simulation study investigating power estimates in Phenome-Wide Association Studies
Verma, A.; Bradford, Y.; Dudek, S.; Verma, S. S.; Pendergrass, S. A.; Ritchie, M. D.
10.1101/115550 — genomics — Posted on 2017-03-12
760 New mutations, old statistical challenges
Barrett, J. C.; Buxbaum, J.; Cutler, D.; Daly, M.; Devlin, B.; Gratten, J.; Hurles, M. E.; Kosmicki, J. A.; Lander, E. S.; MacArthur, D. G.; Neale, B. M.; Roeder, K.; Visscher, P. M.; Wray, N. R.
10.1101/115964 — genetics — Posted on 2017-03-12
761 Functional Characterization of the Morpheus Gene Family
Bekpen, C.; Baker, C.; Hebert, M. D.; Sahin, H. B.; Johnson, M. E.; Celik, A.; Mullikin, J. C.; Comparative Sequencing Program, N.; Eichler, E. E.
10.1101/116087 — evolutionary biology — Posted on 2017-03-12
762 Gut microbiota of the pine weevil degrades conifer diterpenes and increases insect fitness
Berasategui, A.; Salem, H.; Paetz, C.; Santoro, M.; Gershenzon, J.; Kaltenpoth, M.; Schmidt, A.
10.1101/116020 — evolutionary biology — Posted on 2017-03-12
767 Structural basis for EarP-mediated arginine glycosylation of translation elongation factor EF-P
Krafczyk, R.; Macosek, J.; Gast, D.; Wunder, S.; Jagtap, P. K. A.; Mitra, P.; Jha, A. K.; Rohr, J.; Hoffmann-Roeder, A.; Jung, K.; Hennig, J.; Lassak, J.
10.1101/116038 — biochemistry — Posted on 2017-03-11
768 Discovering the Interactions between Circular RNAs and RNA-binding Proteins from CLIP-seq Data using circScan
Li, B.; Zhang, X.-Q.; Liu, S.-R.; Liu, S.; Sun, W.-J.; Lin, Q.; Luo, Y.-X.; Zhou, K.-R.; Zhang, C.-M.; Tan, Y.-Y.; Yang, J.-H.; Qu, L.-H.
10.1101/115980 — molecular biology — Posted on 2017-03-11
769 Common Variant Associations with Fragile X Syndrome
Crowley, J.; Szatkiewicz, J.; Kahler, A.; Giusti-Rodriguez, P.; Ancalade, N.; Booker, J.; Carr, J.; Crawford, G.; Losh, M.; Stockmeier, C.; Taylor, A.; Piven, J.; Sullivan, P. F.
10.1101/115998 — genetics — Posted on 2017-03-11
770 Decoys reveal the genetic and biochemical roles of redundant plant E3 ubiquitin ligases
Lee, C.-M.; Feke, A.; Adamchek, C.; Webb, K.; Pruneda-Paz, J.; Bennett, E. J.; Kay, S. A.; Gendron, J. M.
10.1101/115071 — plant biology — Posted on 2017-03-11
771 Gene expression polymorphism underpins evasion of host immunity in an asexual lineage of the Irish potato famine pathogen
Pais, M.; Yoshida, K.; Giannakopoulou, A.; Pel, M. A.; Cano, L. M.; Oliva, R. F.; Witek, K.; Lindqvist-Kreuze, H.; Vleeshouwers, V. G. A. A.; Kamoun, S.
10.1101/116012 — plant biology — Posted on 2017-03-11
772 Temporal and Clonal Progression in a Pediatric Ependymoma Patient Through Multiple Treatments
Miller, C. A.; Dahiya, S.; Li, T.; Fulton, R.; Smyth, M. D.; Dunn, G. P.; Rubin, J. B.; Mardis, E. R.
10.1101/115923 — cancer biology — Posted on 2017-03-11
774 Multivariate Genome-Wide and Integrated Transcriptome and Epigenome-Wide Analyses of the Well-being Spectrum.
Baselmans, B. M.; Jansen, R.; van Dongen, J.; Bao, Y.; Smart, M.; Kumari, M.; Abdellaoui, A.; van de Weijer, M. P.; Willemsen, G.; Hottenga, J. J.; BIOS consortium, ; Social Science Genetic Association Consortium, ; de Geus, E. J.; Boomsma, D. I.; Nivard, M. G.; Bartels, M.
10.1101/115915 — genetics — Posted on 2017-03-11
779 DEVELOPING GENE-SPECIFIC META-PREDICTOR OF VARIANT PATHOGENICITY
Rychkova, A.; Buu, M. C.; Scharfe, C.; Lefterova, M. I.; Odegaard, J. I.; Schrijver, I.; Milla, C.; Bustamante, C. D.
10.1101/115956 — bioinformatics — Posted on 2017-03-10
781 MODELING SIGNALING-DEPENDENT PLURIPOTENT CELL STATES WITH BOOLEAN LOGIC CAN PREDICT CELL FATE TRANSITIONS
Yachie-Kinoshita, A.; Onishi, K.; Ostblom, J.; Posfai, E.; Rossant, J.; Zandstra, P. W.
10.1101/115683 — systems biology — Posted on 2017-03-10
782 Linking structure and activity in nonlinear spiking networks
Ocker, G. K.; Josić, K.; Shea-Brown, E.; Buice, M. A.
10.1101/080705 — neuroscience — Posted on 2017-03-10
784 Systematic integration of biomedical knowledge prioritizes drugs for repurposing
Himmelstein, D. S.; Lizee, A.; Hessler, C.; Brueggeman, L.; Chen, S. L.; Hadley, D.; Green, A.; Khankhanian, P.; Baranzini, S. E.
10.1101/087619 — bioinformatics — Posted on 2017-03-10
786 MODELING SIGNALING-DEPENDENT PLURIPOTENT CELL STATES WITH BOOLEAN LOGIC CAN PREDICT CELL FATE TRANSITIONS
Yachie-Kinoshita, A.; Onishi, K.; Ostblom, J.; Posfai, E.; Rossant, J.; Zandstra, P. W.
10.1101/115683 — systems biology — Posted on 2017-03-10
788 A homozygous missense mutation in ERAL1, encoding a mitochondrial rRNA chaperone, causes Perrault syndrome
Chatzispyrou, I. A.; Alders, M.; Guerrero-Castillo, S.; Zapata Perez, R.; Haagmans, M. A.; Mouchiroud, L.; Koster, J.; Ofman, R.; Baas, F.; Waterham, H. R.; Spelbrink, J. N.; Auwerx, J.; Mannens, M. M.; Houtkooper, R.; Plomp, A. S.
10.1101/115790 — genetics — Posted on 2017-03-10
794 Identification and characterization of m6A circular RNA epitranscriptomes
Zhou, C.; Molinie, B.; Daneshvar, K.; Pondick, J. V.; Wang, J.; Van Wittenberghe, N. O.; Xing, Y.; Giallourakis, C. C.; Mullen, A. C.
10.1101/115899 — bioinformatics — Posted on 2017-03-10
800 Neurons define non-myelinated axon segments by the regulation of galectin-4-containingaxon membrane domains
Diez-Revuelta, N.; Higuero, A. M.; Velasco, S.; Penas-de-la-Iglesia, M.; Gabius, H.-J.; Abad-Rodriguez, J.
10.1101/115758 — neuroscience — Posted on 2017-03-10
801 Widespread paleopolyploidy, gene tree conflict, and recalcitrant relationships among the carnivorous Caryophyllales
Walker, J. F.; Yang, Y.; Moore, M. J.; Mikenas, J.; Timoneda, A.; Brockington, S. F.; Smith, S. A.
10.1101/115741 — evolutionary biology — Posted on 2017-03-10
805 Psychiatric Genomics: An Update and an Agenda
Sullivan, P. F.; Agrawal, A.; Bulik, C.; Andreassen, O. A.; Borglum, A.; Breen, G.; Cichon, S.; Edenberg, H.; Faraone, S. V.; Gelernter, J.; Mathews, C. A.; Nievergelt, C. M.; Smoller, J.; O'Donovan, M.; Psychiatric Genomics Consortium,
10.1101/115600 — genetics — Posted on 2017-03-10
810 Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.
Evans, L.; Tahmasbi, R.; Vrieze, S.; Abecasis, G.; Das, S.; Bjelland, D.; deCandia, T.; Haplotype Reference Consortium, ; Goddard, M.; Neale, B.; Yang, J.; Visscher, P.; Keller, M.
10.1101/115527 — genetics — Posted on 2017-03-10
812 Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.
Evans, L.; Tahmasbi, R.; Vrieze, S.; Abecasis, G.; Das, S.; Bjelland, D.; deCandia, T.; Haplotype Reference Consortium, ; Goddard, M.; Nealie, B.; Yang, J.; Visscher, P.; Keller, M.
10.1101/115527 — genetics — Posted on 2017-03-09
814 Rapid genome recoding by iterative recombineering of synthetic DNA
Lau, Y. H.; Stirling, F.; Kuo, J.; Karrenbelt, M. A.; Chan, Y. A.; Riesselman, A.; Horton, C. A.; Schaefer, E.; Lips, D.; Weinstock, M. T.; Gibson, D. G.; Way, J. C.; Silver, P. A.
10.1101/115493 — synthetic biology — Posted on 2017-03-09
818 Transcriptomic Description of an Endogenous Female State in C. elegans
Angeles-Albores, D.; Leighton, D. H. W.; Tsou, T.; Khaw, T. H.; Antoshechkin, I.; Sternberg, P.
10.1101/083113 — genetics — Posted on 2017-03-09
824 OME Files - An open source reference library for the OME-XML metadata model and the OME-TIFF file format
Leigh, R.; Gault, D.; Linkert, M.; Burel, J.-M.; Moore, J.; Besson, S.; Swedlow, J. R.
10.1101/088740 — bioinformatics — Posted on 2017-03-09
827 Master manipulation continued: feminizing Wolbachia endosymbiont distorts sex chromosome inheritance
Kageyama, D.; Ohno, M.; Sasaki, T.; Yoshido, A.; Konagaya, T.; Jouraku, A.; Kuwazaki, S.; Kanamori, H.; Katayose, Y.; Narita, S.; Miyata, M.; Riegler, M.; Sahara, K.
10.1101/115386 — evolutionary biology — Posted on 2017-03-09
828 Maintaining maximal metabolic flux by gene expression control
Planque, R.; Hulshof, J.; Teusink, B.; Hendriks, J.; Bruggeman, F. J.
10.1101/115428 — systems biology — Posted on 2017-03-09
829 LASSIM - a network inference toolbox for genome-wide mechanistic modeling
Magnusson, R.; Mariotti, G. P.; Kopsen, M.; Lovfors, W.; Gawel, D. R.; Jornsten, R.; Linde, J.; Nordling, T.; Nyman, E.; Schulze, S.; Nestor, C. E.; Zhang, H.; Cedersund, G.; Benson, M.; Tjarnberg, A.; Gustafsson, M.
10.1101/115477 — systems biology — Posted on 2017-03-09
830 Multiple reference genome sequences of hot pepper reveal the massive evolution of plant disease resistance genes by retroduplication
Kim, S.; Park, J.; Yeom, S.-I.; Kim, Y.-M.; Seo, E.; Kim, K.-T.; Kim, M.-S.; Lee, J. M.; Cheong, K.; Shin, H.-S.; Kim, S.-B.; Han, K.; Lee, J.; Park, M.; Lee, H.-A.; Lee, H.-Y.; Lee, Y.; Oh, S.; Lee, J. H.; Choi, E.; Choi, E.; Lee, S. E.; Jeon, J.; Kim, H.; Choi, G.; Song, H.; Lee, J.; Lee, S.-C.; Kwon, J.-K.; Lee, H.-Y.; Koo, N.; Hong, Y.; Kim, R. W.; Kang, W.-H.; Huh, J. H.; Kang, B.-C.; Yang, T.-J.; Lee, Y.-H.; Bennetzen, J. L.; Choi, D.
10.1101/115410 — plant biology — Posted on 2017-03-09
832 From the statistics of connectivity to the statistics of spike times in neuronal networks
Ocker, G. K.; Hu, Y.; Buice, M. A.; Doiron, B.; Josić, K.; Rosenbaum, R.; Shea-Brown, E.
10.1101/115402 — neuroscience — Posted on 2017-03-09
835 ChromoTrace: Reconstruction of 3D Chromosome Configurations by Super-Resolution Microscopy
Morganella, S.; Oedegaard, O.; Alexander, S.; Ries, J.; Fitzgerald, T.; Ellenberg, J.; Birney, E.
10.1101/115436 — bioinformatics — Posted on 2017-03-09
836 Managed woodlot revealed a trade-off between edible leaves and timber production in Vitex doniana Sweet (Lamiaceae)
N'Danikou, S.; Tchokponhoue, D. A.; Houdegbe, A. C.; Agossou, A. O. C.; Achigan-Dako, E. G.; Assogba Komlan, F.; Vodouhe, R. S.; Ahanchede, A.
10.1101/115154 — plant biology — Posted on 2017-03-09
839 First landscape of binding to chromosomes for a domesticated mariner transposase in the human genome: diversity of genomic targets of SETMAR isoforms in two colorectal cell lines
Antoine-Lorquin, A.; Arnoaty, A.; Asgari, S.; Batailler, M.; Beauclair, L.; Bire, S.; Buisine, N.; Coustham, V.; Girault, A.; Guyetant, S.; Lecomte, T.; Piegu, B.; Pitard, B.; Stevant, I.; Belleannee, C.; Bigot, Y.
10.1101/115030 — genomics — Posted on 2017-03-09
845 DroNc-Seq: Deciphering cell types in human archived brain tissues by massively-parallel single nucleus RNA-seq
Habib, N.; Basu, A.; Avraham-Davidi, I.; Burks, T.; Choudhury, S. R.; Aguet, F.; Gelfand, E.; Ardlie, K.; Weitz, D. A.; Rozenblatt-Rosen, O.; Zhang, F.; Regev, A.
10.1101/115196 — genomics — Posted on 2017-03-09
847 OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes
Piazza, R.; Ramazzotti, D.; Spinelli, R.; Pirola, A.; De Sano, L.; Ferrari, P.; Magistroni, V.; Cordani, N.; Sharma, N.; Gambacorti-Passerini, C.
10.1101/115329 — bioinformatics — Posted on 2017-03-09
849 Resistance genes in global crop breeding networks
Garrett, K.; Andersen, K.; Asche, F.; Bowden, R.; Forbes, G.; Kulakow, P.; Zhou, B.
10.1101/106484 — genetics — Posted on 2017-03-09
853 The Effects of Practice-based Training on Graduate Teaching Assistants’ Classroom Practices
Becker, E. A.; Easlon, E. J.; Potter, S. C.; Guzman-Alvarez, A.; Spear, J. M.; Facciotti, M. T.; Igo, M. M.; Singer, M.; Pagliarulo, C.
10.1101/115295 — scientific communication and education — Posted on 2017-03-08
855 Synaptic and peptidergic connectome of a neurosecretory centre in the annelid brain
Williams, E. A.; Veraszto, C.; Jasek, S.; Conzelmann, M.; Shahidi, R.; Bauknecht, P.; Jekely, G.
10.1101/115204 — neuroscience — Posted on 2017-03-08
856 Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity
Meers, M. P.; Henriques, T.; Lavender, C. A.; McKay, D. J.; Strahl, B. D.; Duronio, R. J.; Adelman, K.; Matera, A. G.
10.1101/114926 — molecular biology — Posted on 2017-03-08
864 Ankyrin-1 gene exhibits allelic heterogeneity in conferring protection against malaria
Huang, H. M.; Bauer, D.; Lelliott, P.; Dixon, M.; Tilley, L.; McMorran, B.; Foote, S.; Burgio, G.
10.1101/114959 — microbiology — Posted on 2017-03-08
865 Transcriptomic profiling of high-density Giardia foci encysting in the murine proximal intestine
Pham, J. K.; Nosala, C.; Scott, E. Y.; Nguyen, K. F.; Hagen, K. D.; Starcevich, H. N.; Dawson, S. C.
10.1101/114983 — microbiology — Posted on 2017-03-08
866 Plasmid DNA analysis of pristine groundwater microbial communities reveal extensive presence of metal resistance genes
Kothari, A.; Wu, Y.-W.; Charrier, M.; Rajeev, L.; Rocha, A. M.; Paradis, C. J.; Hazen, T. C.; Singer, S. W.; Mukhopadhyay, A.
10.1101/113860 — microbiology — Posted on 2017-03-08
873 ES cell derived neural progenitors improves visual functions in retinal ganglion cells - depleted mouse models
Mundackal Sivaraman, D.; Vazhanthodi Abdul, R.; Schmidt, T.; Soundararajan, L.; Hattar, S.; James, J.
10.1101/114678 — cell biology — Posted on 2017-03-08
877 High-resolution TADs reveal DNA sequences underlying genome organization in flies
Ramirez, F.; Bhardwaj, V.; Villaveces, J.; Arrigoni, L.; Gruening, B. A.; Lam, K. C.; Habermann, B.; Akhtar, A.; Manke, T.
10.1101/115063 — genomics — Posted on 2017-03-08
878 Genetics of educational attainment aid in identifying biological subcategories of schizophrenia
Bansal, V.; Mitjans, M.; Burik, C. A. P.; Karlsson Linner, R.; Okbay, A.; Rietveld, C. A.; Begemann, M.; Bonn, S.; Ripke, S.; Nivard, M. G.; Ehrenreich, H.; Koellinger, P. D.
10.1101/114405 — genetics — Posted on 2017-03-08
879 Climate change promotes hybridisation between deeply divergent species
Canestrelli, D.; Bisconti, R.; Chiocchio, A.; Maiorano, L.; Zampiglia, M.; Nascetti, G.
10.1101/066258 — evolutionary biology — Posted on 2017-03-08
881 Social interactions within the family enhance the capacity for evolutionary change
Jarrett, B. J. M.; Schrader, M.; Rebar, D.; Houslay, T. M.; Kilner, R. M.
10.1101/115014 — evolutionary biology — Posted on 2017-03-08
883 Epigenetic Regulation of Gene Expression in Cancer: Techniques, Resources, and Analysis
Kagohara, L.; Stein-O'Brien, G.; Kelley, D.; Flam, E.; Wick, H.; Danilova, L.; Easwaran, H.; Favorov, A.; Qian, J.; Gaykalova, D.; Fertig, E.
10.1101/114025 — cancer biology — Posted on 2017-03-08
885 MicroRNA exocytosis by large dense-core vesicle fusion
Gumurdu, A.; Yildiz, R.; Eren, E.; Karakulah, G.; Unver, T.; Genc, S.; Park, Y.
10.1101/093278 — neuroscience — Posted on 2017-03-08
888 A hierarchical Bayesian framework for understanding the spatiotemporal dynamics of the intestinal epithelium
Maclaren, O. J.; Parker, A.; Pin, C.; Carding, S. R.; Watson, A. J.; Fletcher, A. G.; Byrne, H. M.; Maini, P. K.
10.1101/072561 — systems biology — Posted on 2017-03-08
889 1/f neural noise is a better predictor of schizophrenia than neural oscillations
Peterson, E. J.; Rosen, B. Q.; Campbell, A. M.; Belger, A.; Voytek, B.
10.1101/113449 — neuroscience — Posted on 2017-03-08
892 Application of t-SNE to Human Genetic Data
Li, W.; Cerise, J. E.; Yang, Y.; Han, H.
10.1101/114884 — genetics — Posted on 2017-03-08
898 Alphaproteobacteria fix nitrogen in a Sphagnum-dominated peat bog using molybdenum-dependent nitrogenase
Warren, M. J.; Lin, X.; Gaby, J. C.; Kretz, C. B.; Morton, P. L.; Pett-Ridge, J.; Weston, D. J.; Schadt, C. W.; Kostka, J. E.; Glass, J. B.
10.1101/114918 — microbiology — Posted on 2017-03-07
899 Polymorphic Dynamics of Ribosomal Proteins′ Gene Expression during Induced Pluripotency
Guthikonda, P. K.; Bharathan, S. P.; Rayabaram, J.; Yellaboina, S.; Velayudhan, S. R.; Kurukuti, S.
10.1101/114868 — developmental biology — Posted on 2017-03-07
901 Post-mortem molecular profiling of three psychiatric disorders
Bowling, K.; Ramaker, R. C.; Lasseigne, B. N.; Hagenauer, M.; Hardigan, A.; Davis, N.; Gertz, J.; Cartagena, P.; Walsh, D.; Vawter, M.; Schatzberg, A.; Barchas, J.; Watson, S.; Bunney, B.; Akil, H.; Bunney, W.; Li, J.; Cooper, S.; Myers, R. M.
10.1101/061416 — genomics — Posted on 2017-03-07
905 A powerful approach to estimating annotation-stratified genetic covariance using GWAS summary statistics
Lu, Q.; Li, B.; Ou, D.; Erlendsdottir, M.; Powles, R. L.; Jiang, T.; Hu, Y.; Chang, D.; Jin, C.; Dai, W.; He, Q.; Liu, Z.; Mukherjee, S.; Crane, P. K.; Zhao, H.
10.1101/114561 — genetics — Posted on 2017-03-07
909 Association of pre-pregnancy body mass index with future offspring metabolic profile: findings from three independent European birth cohorts
Santos Ferreira, D. L.; Williams, D. M.; Kangas, A. J.; Soininen, P.; Ala-Korpela, M.; Smith, G. D.; Jarvelin, M.-R.; Lawlor, D. A.
10.1101/114413 — epidemiology — Posted on 2017-03-07
910 On the genetic and environmental reasons why intelligence correlates with criminal victimization
Boutwell, B.; Connolly, E.; Barbaro, N.; Shackelford, T.; Petkovsek, M.; Beaver, K.
10.1101/113712 — epidemiology — Posted on 2017-03-07
912 Genome-Wide Analysis of Facial Regionalization in Zebrafish
Askary, A.; Xu, P.; Barske, L.; Bay, M.; Bump, P.; Balczerski, B.; Bonaguidi, M. A.; Crump, G.
10.1101/114801 — developmental biology — Posted on 2017-03-07
915 A DNA demethylase overexpression promotes early apical bud maturation in poplar through the biosynthesis and accumulation of flavonoids
Conde, D.; Moreno-Cortes, A.; Dervinis, C.; Ramos-Sanchez, J. M.; Kirst, M.; Perales, M.; Gonzalez-Melendi, P.; Allona, I.
10.1101/114652 — plant biology — Posted on 2017-03-07
916 INCLUSION CRITERIA UPDATE OF THE INTRALUMINAL ISCHEMIC MODEL IN RAT FOR PRECLINICAL STUDIES
Fernandez-Susavila, H.; Iglesias Rey, R.; Dopico-Lopez, A.; Perez-Mato, M.; Sobrino, T.; Castillo, J.; Campos, F.
10.1101/114629 — neuroscience — Posted on 2017-03-07
918 An epigenome-wide association study of educational attainment (n = 10,767)
Karlsson Linner, R.; Marioni, R. E.; Rietveld, C. A.; Simpkin, A.; Davies, N. M.; Watanabe, K.; Armstrong, N. J.; Auro, K.; Baumbach, C.; Bonder, M. J.; Buchwald, J.; Fiorito, G.; Ismail, K.; Iurato, S.; Joensuu, A.; Karell, P.; Kasela, S.; Lahti, J.; McRae, A. F.; Mandaviya, P. R.; Seppala, I.; Wang, Y.; Baglietto, L.; Binder, E. B.; Harris, S. E.; Hodge, A. M.; Horvath, S.; Hurme, M.; Johannesson, M.; Latvala, A.; Mather, K. A.; Medland, S. E.; Metspalu, A.; Milani, L.; Milne, R. L.; Pattie, A.; Pedersen, N. L.; Peters, A.; Polidoro, S.; Raikkonen, K.; Severi, G.; Starr, J. M.; Stolk, L.; Wa
10.1101/114637 — genetics — Posted on 2017-03-07
920 The molecular weight of NaYF4:RE photonic up-conversion nanoparticles
MacKenzie, L. E.; Goode, J. A.; Vakurov, A.; Nampi, P. P.; Saha, S.; Jose, G.; Millner, P. A.
10.1101/114744 — biophysics — Posted on 2017-03-07
921 Scaling up DNA data storage and randomaccess retrieval
Organick, L.; Ang, S. D.; Chen, Y.-J.; Lopez, R.; Yekhanin, S.; Makarychev, K.; Racz, M. Z.; Kamath, G.; Gopalan, P.; Nguyen, B.; Takahashi, C.; Newman, S.; Parker, H.-Y.; Rashtchian, C.; Stewart, K.; Gupta, G.; Carlson, R.; Mulligan, J.; Carmean, D.; Seelig, G.; Ceze, L.; Strauss, K.
10.1101/114553 — bioengineering — Posted on 2017-03-07
922 Prophage genomics reveals patterns in phage genome organization and replication
Kang, H. S.; McNair, K.; Cuevas, D.; Bailey, B.; Segall, A.; Edwards, R. A.
10.1101/114819 — biochemistry — Posted on 2017-03-07
924 Effective purifying selection in ancient asexual oribatid mites
Brandt, A.; Schaefer, I.; Glanz, J.; Schwander, T.; Maraun, M.; Scheu, S.; Bast, J.
10.1101/112458 — evolutionary biology — Posted on 2017-03-07
925 Alzheimer related genes show accelerated evolution
Nitsche, A.; Reiche, K.; Ueberham, U.; Arnold, C.; Hackermueller, J.; Horn, F.; Stadler, P. F.; Arendt, T.
10.1101/114108 — evolutionary biology — Posted on 2017-03-07
926 Can malaria parasites manipulate the odour-mediated host preference of their mosquito vectors?
Nguyen, P. L.; Vantaux, A.; Hien, D. F.; Dabire, K. R.; Yameogo, B.; Gouagna, L.-C.; Fontenille, D.; Renaud, F.; Simard, F.; Constantini, C.; Thomas, F.; Cohuet, A.; Lefevre, T.
10.1101/114272 — evolutionary biology — Posted on 2017-03-07
928 The interplay of demography and selection during maize domestication and expansion
Wang, L.; Beissinger, T. M.; Lorant, A.; Ross-Ibarra, C.; Ross-Ibarra, J.; Hufford, M.
10.1101/114579 — evolutionary biology — Posted on 2017-03-07
931 Mutation supply and the repeatability of selection for antibiotic resistance
van Dijk, T.; Hwang, S.; Krug, J.; de Visser, J. A. G. M.; Zwart, M. P.
10.1101/114322 — evolutionary biology — Posted on 2017-03-07
932 Odor concentration change detectors in the Olfactory Bulb
Parabucki, A.; Bizer, A.; Morris, G.; Smear, M. C.; Shusterman, R.
10.1101/114520 — neuroscience — Posted on 2017-03-07
941 Dramatic differences in gut bacterial densities help to explain the relationship between diet and habitat in rainforest ants
Sanders, J. G.; Łukasik, P.; Frederickson, M.; Russell, J.; Koga, R.; Knight, R.; Pierce, N.
10.1101/114512 — ecology — Posted on 2017-03-07
943 TRPV1 activation relies on hydration/dehydration of nonpolar cavities
Kasimova, M.; Yazici, A.; Granata, D.; Klein, M. L.; Rohacs, T.; Carnevale, V.
10.1101/114546 — biophysics — Posted on 2017-03-06
946 Adaptive pathways of coral populations on the Great Barrier Reef
Matz, M. V.; Treml, E. A.; Aglyamova, G. V.; van Oppen, M. J. H.; Bay, L. K.
10.1101/114173 — evolutionary biology — Posted on 2017-03-06
947 Bird interactions with drones, from individuals to large colonies
Lyons, M.; Brandis, K.; Callaghan, C.; McCann, J.; Mills, C.; Ryall, S.; Kingsford, R.
10.1101/109926 — ecology — Posted on 2017-03-06
948 Sorting of molecular shuttles by designing electrical and mechanical properties of microtubules
Isozaki, N.; Shintaku, H.; Kotera, H.; Hawkins, T. L.; Ross, J. L.; Yokokawa, R.
10.1101/107458 — bioengineering — Posted on 2017-03-06
949 Parallel ancient genomic transects reveal complex population history of early European farmers
Lipson, M.; Szecsenyi-Nagy, A.; Mallick, S.; Posa, A.; Stegmar, B.; Keerl, V.; Rohland, N.; Stewardson, K.; Ferry, M.; Michel, M.; Oppenheimer, J.; Broomandkhoshbacht, N.; Harney, E.; Nordenfelt, S.; Llamas, B.; Mende, B. G.; Kohler, K.; Oross, K.; Bondar, M.; Marton, T.; Osztas, A.; Jakucs, J.; Paluch, T.; Horvath, F.; Csengeri, P.; Koos, J.; Sebok, K.; Anders, A.; Raczky, P.; Regenye, J.; Barna, J. P.; Fabian, S.; Serlegi, G.; Toldi, Z.; Nagy, E. G.; Dani, J.; Molnar, E.; Palfi, G.; Mark, L.; Melegh, B.; Banfai, Z.; Fernandez-Eraso, J.; Mujika-Alustiza, J. A.; Alonso Fernandez, C.; Jimenez E
10.1101/114488 — genetics — Posted on 2017-03-06
953 Demonstration of de novo chemotaxis in E. coli using a real-time, quantitative, and digital-like approach
Davidov, T.; Granik, N.; Zahran, S.; Adir, I.; Elul, O.; Fried, T.; Gil, A.; Mayo, B.; Ohayon, S.; Sarig, S.; Shasha, N.; Tsedef, S.; Weiner, S.; Brunwasser-Meirom, M.; Ereskovsky, A.; Katz, N.; Kaufmann, B.; Haimov, Y.; Leonard, H.; Segal, E.; Amit, R.
10.1101/114207 — synthetic biology — Posted on 2017-03-06
954 Court and spark in the wild: communication at the limits of sensation
Henninger, J.; Kirschbaum, F.; Grewe, J.; Krahe, R.; Benda, J.
10.1101/114249 — neuroscience — Posted on 2017-03-06
955 Differences in the spatial and temporal patterns of head motion during MRI of adults and infants
Cusack, R.; Linke, A.; Zubiaurre-Elorza, L.; Duffy, H.; Herzmann, C.; Stojanoski, B.; Han, V.; Lee, D. S.; Wild, C.
10.1101/114447 — neuroscience — Posted on 2017-03-06
959 Metabolic coupling in bacteria
Shitut, S.; Ahsendorf, T.; Pande, S.; Egbert, M.; Kost, C.
10.1101/114462 — microbiology — Posted on 2017-03-06
960 Natural Colonization of Laboratory Mice with Staphylococcus aureus Primes a Systemic Immune Response
Schulz, D.; Grumann, D.; Truebe, P.; Pritchett-Corning, K.; Johnson, S.; Reppschlaeger, K.; Gumz, J.; Sundaramoorthy, N.; Michalik, S.; Berg, S.; van den Brandt, J.; Fister, R.; Monecke, S.; Uy, B.; Schmidt, F.; Broeker, B. M.; Wiles, S.; Holtfreter, S.
10.1101/114314 — immunology — Posted on 2017-03-06
961 The fitness cost of mis-splicing is the main determinant of alternative splicing patterns
Saudemont, B.; Popa, A.; Parmley, J. L.; Rocher, V.; Blugeon, C.; Necsulea, A.; Meyer, E.; Duret, L.
10.1101/114215 — genomics — Posted on 2017-03-06
962 CRISPR/Cas9 screening using unique molecular identifiers
Schmierer, B.; Botla, S. K.; Zhang, J.; Turunen, M.; Kivioja, T.; Taipale, J.
10.1101/114355 — genomics — Posted on 2017-03-06
963 Whole genome methylation analysis of non-dysplastic Barretts oesophagus that progresses to invasive cancer
Dilworth, M. P.; Nieto, T.; Stockton, J. D.; Whalley, C. M.; Tee, L.; James, J. D.; Hallissey, M. T.; Hejmadi, R.; Trugdill, N.; Tucker, O.; Beggs, A. D.
10.1101/114298 — genomics — Posted on 2017-03-06
965 Mutation supply and the repeatability of selection for antibiotic resistance
van Dijk, T.; Hwang, S.; Krug, J.; de Visser, J. A. G. M.; Zwart, M. P.
10.1101/114322 — evolutionary biology — Posted on 2017-03-06
969 Connexin43 controls N-cadherin transcription during collective cell migration
Kotini, M.; Barriga, E.; Leslie, J.; Gentzel, M.; Schambony, A.; Mayor, R.
10.1101/114371 — developmental biology — Posted on 2017-03-06
972 QuPath: Open source software for digital pathology image analysis
Bankhead, P.; Loughrey, M. B.; Fernandez, J. A.; Dombrowski, Y.; McArt, D. G.; Dunne, P. D.; McQuaid, S.; Gray, R. T.; Murray, L. J.; Coleman, H. G.; James, J. A.; Salto-Tellez, M.; Hamilton, P. W.
10.1101/099796 — bioinformatics — Posted on 2017-03-06
978 Dipolar extracellular potentials generated by axonal projections
McColgan, T.; Liu, J.; Kuokkanen, P. T.; Carr, C. E.; Hermann, W.; Kempter, R.
10.1101/109918 — neuroscience — Posted on 2017-03-06
981 Dengue fever and Aedes aegypti risk in the Galapagos Islands, Ecuador
Nightingale, R.; Lippi, C. A.; Ryan, S. J.; Borbor-Cordova, M. J.; Cruz B, M.; Ortega, F.; Leon, R.; Waggoner, E.; Stewart Ibarra, A. M.
10.1101/113829 — epidemiology — Posted on 2017-03-06
982 Vaccination of health care workers to control Ebola virus disease
Robert, A.; Camacho, A.; Edmunds, W. J.; Baguelin, M.; Muyembe Tamfum, J.-J.; Rosello, A.; Keita, S.; Eggo, R. M.
10.1101/113506 — epidemiology — Posted on 2017-03-06
983 Association between Mitochondrial DNA Copy Number and Sudden Cardiac Death: Findings from the Atherosclerosis Risk in Communities Study (ARIC)
Zhang, Y.; Guallar, E.; Ashar, F.; Longchamps, R.; Castellani, C.; Lane, J.; Grove, M.; Coresh, J.; Sotoodehnia, N.; Ilkhanoff, L.; Boerwinkle, E.; Pankratz, N.; Arking, D.
10.1101/113878 — epidemiology — Posted on 2017-03-06
985 Metaviz: interactive statistical and visual analysis of metagenomic data
Wagner, J.; Chelaru, F.; Kancherla, J.; Paulson, J. N.; Felix, V.; Mahurkar, A.; Corrada Bravo, H.
10.1101/105205 — bioinformatics — Posted on 2017-03-06
986 Sorting of molecular shuttles by designing electrical and mechanical properties of microtubules
Isozaki, N.; Shintaku, H.; Kotera, H.; Hawkins, T. L.; Ross, J. L.; Yokokawa, R.
10.1101/107458 — bioengineering — Posted on 2017-03-06
987 Information theoretic evidence for predictive coding in the face processing system
Brodski-Guerniero, A.; Paasch, G.-F.; Wollstadt, P.; Oezdemir, I.; Lizier, J. T.; Wibral, M.
10.1101/089300 — neuroscience — Posted on 2017-03-06
988 Reduced representation optical methylation mapping (R2OM2).
Grunwald, A.; Sharim, H.; Gabrieli, T.; Michaeli, Y.; Torchinsky, D.; Juhasz, M.; Reifenberger, J.; Hastie, A. R.; Cao, H.; Weinhold, E.; Ebenstein, Y.
10.1101/108084 — genetics — Posted on 2017-03-06
992 Quantitative monitoring of multispecies fish environmental DNA using high-throughput sequencing
Ushio, M.; Murakami, H.; Masuda, R.; Sado, T.; Miya, M.; Sakurai, S.; Yamanaka, H.; Minamoto, T.; Kondoh, M.
10.1101/113472 — ecology — Posted on 2017-03-05
993 Mindcontrol: A Web Application for Brain Segmentation Quality Control
Keshavan, A.; Datta, E.; McDonough, I.; Madan, C. R.; Jordan, K.; Henry, R.
10.1101/090431 — bioinformatics — Posted on 2017-03-05
994 NLR1-V, a CC-NBS-LRR encoding gene, is a potential candidate gene of the wheat powdery mildew resistance gene Pm21
Xing, L.; Hu, P.; Liu, J.; Cui, C.; Wang, H.; Di, Z.; Zhou, S.; Xu, J.; Gao, L.; Huang, Z.; Cao, A.
10.1101/114058 — plant biology — Posted on 2017-03-05
996 Genetic polymorphism of Cytochrome-P450-2C9 (CYP2C9) in Indian populations
Nizamuddin, S.; Dubey, S.; Singh, S.; Sharma, S.; Mishra, A.; K, H.; Joshi, H.; Thangaraj, K.
10.1101/113993 — evolutionary biology — Posted on 2017-03-05
997 The language oscillogenome
Murphy, E.; Benitez-Burraco, A.
10.1101/114033 — neuroscience — Posted on 2017-03-05
998 HOT or not: Examining the basis of high-occupancy target regions
Wreczycka, K.; Franke, V.; Uyar, B.; Wurmus, R.; AKALIN, A.
10.1101/107680 — genomics — Posted on 2017-03-05
1006 Improved annotation of the insect vector of Citrus greening disease: Biocuration by a diverse genomics community
Saha, S.; Hosmani, P. S.; Villalobos-Ayala, K.; Miller, S.; Shippy, T.; Rosendale, A.; Cordola, C.; Bell, T.; Mann, H.; DeAvila, G.; DeAvila, D.; Moore, Z.; Buller, K.; Ciolkevich, K.; Nandyal, S.; Mahoney, R.; Voorhis, J. V.; Dunlevy, M.; Farrow, D.; Hunter, D.; Morgan, T.; Shore, K.; Guzman, V.; Izsak, A.; Dixon, D. E.; Cano, L.; Cridge, A.; Johnson, S.; Cantarel, B. L.; Richardson, S.; English, A.; Leng, N.; Cao, X.; Jiang, H.; Shatters, R. G.; Childers, C.; Chen, M.-J.; Flores, M.; Hunter, W.; Cilia, M.; Mueller, L. A.; Munoz-Torres, M.; Nelson, D.; Poelchau, M. F.; Benoit, J.; Wiersma-Koc
10.1101/099168 — genomics — Posted on 2017-03-04
1013 Multi-scale Bayesian modeling of cryo-electron microscopy density maps
Hanot, S.; Bonomi, M.; Greenberg, C. H.; Sali, A.; Nilges, M.; Vendruscolo, M.; Pellarin, R.
10.1101/113951 — bioinformatics — Posted on 2017-03-04
1014 Nests of red wood ants (Formica rufa-group) are positively associated with tectonic faults: a double-blind test
Del Toro, I.; Berberich, G.; Ribbons, R. R.; Berberich, M. B.; Sanders, N. J.; Ellison, A. M.
10.1101/113571 — ecology — Posted on 2017-03-04
1017 A Statistical Model of Shared Variability in the Songbird Auditory System
Buesing, L.; Calabrese, A.; Cunningham, J.; Woolley, S.; Paninski, L.
10.1101/113670 — neuroscience — Posted on 2017-03-04
1019 Identification of drug candidates that enhance pyrazinamide activity from a clinical drug library
Niu, H.; Ma, C.; Cui, P.; Shi, W.; Zhang, S.; Feng, J.; Sullivan, D.; Zhu, B.; Zhang, W.; Zhang, Y.
10.1101/113704 — microbiology — Posted on 2017-03-04
1020 Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity
Snarr, B. D.; Baker, P.; Bamford, N. C.; Sato, Y.; Liu, H.; Lehoux, M.; Gravelat, F. N.; Ostapska, H.; Baistrocchi, S. R.; Cerone, R. P.; Filler, E. E.; Parsek, M. R.; Filler, S. G.; Howell, P. L.; Sheppard, D. C.
10.1101/113696 — microbiology — Posted on 2017-03-04
1021 Humans are colonized by many uncharacterized and highly divergent microbes
Kowarsky, M. A.; Camunas-Soler, J.; Kertesz, M.; De Vlaminck, I.; Koh, L. C. W.; Pan, W.; Martin, L.; Neff, N.; Okamoto, J.; Wong, R. J.; Kharbanda, S.; El-Sayed, Y.; Blumenfeld, Y.; Stevenson, D. K.; Shaw, G. M.; Wolfe, N. D.; Quake, S. R.
10.1101/113746 — microbiology — Posted on 2017-03-04
1030 REPARATION: Ribosome Profiling Assisted (Re-)Annotation of Bacterial genomes.
Ndah, E.; Jonckheere, V.; Giess, A.; Valen, E.; Menschaert, G.; Van Damme, P.
10.1101/113530 — microbiology — Posted on 2017-03-03
1031 Development of a Novel CD4+ TCR Transgenic Line that Reveals a Dominant Role for CD8+ DC and CD40-Signaling in the Generation of Helper and CTL Responses to Blood Stage Malaria
Fernandez-Ruiz, D.; Lau, L. S.; Ghazanfari, N.; Jones, C. M.; Ng, W. Y.; Davey, G. M.; Berthold, D.; Holz, L.; Kato, Y.; Bayarsaikhan, G.; Hendriks, S. H.; James, K. R.; Cozijnsen, A.; Mollard, V.; De Koning-Ward, T.; Gilson, P.; Kaisho, T.; Haque, A.; Crabb, B. S.; Carbone, F. R.; McFadden, G. I.; Heath, W.
10.1101/113837 — immunology — Posted on 2017-03-03
1032 Reduced representation optical methylation mapping (R2OM2).
Grunwald, A.; Sharim, H.; Gabrieli, T.; Michaeli, Y.; Torchinsky, D.; Juhasz, M.; Wagner, K. R.; Pevsner, J.; Reifenberger, J.; Hastie, A. R.; Cao, H.; Weinhold, E.; Ebenstein, Y.
10.1101/113522 — genetics — Posted on 2017-03-03
1034 Representing Genetic Determinants in BacterialGWAS with Compacted De Bruijn Graphs
Jaillard, M.; Tournoud, M.; Lima, L.; Lacroix, V.; Veyrieras, J.-B.; Jacob, L.
10.1101/113563 — bioinformatics — Posted on 2017-03-03
1035 Short term changes in the proteome of human cerebral organoids induced by 5-methoxy-N,N-dimethyltryptamine
Dakic, V.; Nascimento, J. M.; Sartore, R. C.; de Moraes Maciel, R.; de Araujo, D. B.; Ribeiro, S.; Martins-de-Souza, D.; Rehen, S. K.
10.1101/108159 — neuroscience — Posted on 2017-03-03
1036 Genomic diagnosis for children with intellectual disability and/or developmental delay
Bowling, K. M.; Thompson, M. L.; Amaral, M. D.; Finnila, C. R.; Hiatt, S. M.; Engel, K. L.; Cochran, J. N.; Brothers, K. B.; East, K. M.; Gray, D. E.; Kelley, W. V.; Lamb, N. E.; Lose, E. J.; Rich, C. A.; Simmons, S.; Whittle, J. S.; Weaver, B. T.; Nesmith, A. S.; Myers, R. M.; Barsh, G. S.; Bebin, E. M.; Cooper, G. M.
10.1101/084251 — genomics — Posted on 2017-03-03
1038 Large-scale simultaneous measurement of epitopes and transcriptomes in single cells.
Stoeckius, M.; Hafemeister, C.; Stephenson, W.; Houck-Loomis, B.; Swerdlow, H.; Satija, R.; Smibert, P.
10.1101/113068 — genomics — Posted on 2017-03-03
1039 Systematic Design and Comparison of Expanded Carrier Screening Panels
Beauchamp, K. A.; Muzzey, D.; Wong, K. K.; Hogan, G. J.; Karimi, K.; Candille, S. I.; Mehta, N.; Kaseniit, K. E.; Mar-Heyming, R.; Kang, H. P.; Evans, E. A.; Goldberg, J. D.; Lazarin, G. A.; Haque, I. S.
10.1101/080713 — genetics — Posted on 2017-03-03
1040 Genetic characterization of the Zika virus epidemic in the US Virgin Islands
Black, A.; Potter, B.; Dudas, G.; Feldstein, L.; Grubaugh, N. D.; Andersen, K. G.; Ellis, B. R.; Ellis, E. M.; Bedford, T.
10.1101/113100 — epidemiology — Posted on 2017-03-03
1041 1/f neural noise is a better predictor of schizophrenia than neural oscillations
Peterson, E. J.; Rosen, B. Q.; Campbell, A. M.; Belger, A.; Voytek, B.
10.1101/113449 — neuroscience — Posted on 2017-03-03
1045 An indicator cell assay for blood-based diagnostics
Danziger, S. A.; Miller, L. R.; Singh, K.; Whitney, G. A.; Peskind, E. R.; Li, G.; Lipshutz, R. J.; Aitchison, J. D.; Smith, J.
10.1101/113357 — systems biology — Posted on 2017-03-03
1047 1/f neural noise is a better predictor of schizophrenia than neural oscillations
Peterson, E. J.; Rosen, B. Q.; Campbell, A. M.; Belger, A.; Bradley, B.
10.1101/113449 — neuroscience — Posted on 2017-03-03
1051 Myeloablation-associated deletion of ORF4 in a human coronavirus 229E infection
Greninger, A.; Pepper, G.; Shean, R. C.; Cent, A.; Palileo, I.; Kuypers, J. M.; Schiffer, J. T.; Jerome, K. R.
10.1101/113423 — genomics — Posted on 2017-03-03
1052 The Genetic History of Northern Europe
Mittnik, A.; Wang, C.-C.; Pfrengle, S.; Daubaras, M.; Zariņa, G.; Hallgren, F.; Allmae, R.; Khartanovich, V.; Moiseyev, V.; Furtwangler, A.; Andrades Valtuena, A.; Feldman, M.; Economou, C.; Oinonen, M.; Vasks, A.; Torv, M.; Balanovsky, O.; Reich, D.; Jankauskas, R.; Haak, W.; Schiffels, S.; Krause, J.
10.1101/113241 — genetics — Posted on 2017-03-03
1053 Targeted genomic screen reveals focal long non-coding RNA copy number alterations in cancer
Volders, P.-J.; Vandesompele, J.; Lefever, S.; Baute, S.; Nuytens, J.; Vanderheyden, K.; Menten, B.; Mestdagh, P.
10.1101/113316 — genetics — Posted on 2017-03-03
1057 Quantitative monitoring of multispecies fish environmental DNA using high-throughput sequencing
Ushio, M.; Murakami, H.; Masuda, R.; Sado, T.; Miya, M.; Sakurai, S.; Yamanaka, H.; Minamoto, T.; Kondoh, M.
10.1101/113472 — ecology — Posted on 2017-03-03
1062 Dynamics of ASC speck formation during skin inflammatory responses in vivo
Kuri, P.; Schieber, N.; Thumberger, T.; Wittbrodt, J.; Schwab, Y.; Leptin, M.
10.1101/111542 — immunology — Posted on 2017-03-03
1063 Genetic characterization of the Zika virus epidemic in the US Virgin Islands
Black, A.; Potter, B.; Dudas, G.; Feldstein, L.; Grubaugh, N. D.; Andersen, K. G.; Ellis, B. R.; Ellis, E. M.; Bedford, T.
10.1101/113100 — epidemiology — Posted on 2017-03-03
1067 DHX15 regulates CMTR1-dependent gene expression and cell proliferation
Inesta-Vaquera, F.; Galloway, A.; Chandler, L.; Rojas-Fernandez, A.; Chaugule, V. K.; Weidlich, S.; Peggie, M.; Cowling, V. H.
10.1101/113209 — cell biology — Posted on 2017-03-03
1068 Cartilage microRNA dysregulation during the onset and progression of mouse osteoarthritis overlaps with patient disease candidates
Kung, L. H. W.; Ravi, V.; Rowley, L.; Angelucci, C.; Fosang, A. J.; Bell, K. M.; Little, C. B.; Bateman, J.
10.1101/113456 — cell biology — Posted on 2017-03-03
1072 Development of Narrow Spectrum ATP-competitive Kinase Inhibitors as Probes for BIKE and AAK1
Counago, R. M.; Axtman, A. D.; Capuzzi, S. J.; Azevedo, H.; Drewry, D. H.; Elkins, J. M.; Gileadi, O.; Guimaraes, C. R. W.; Mascarello, A.; Serafim, R. A. M.; Wells, C. I.; Willson, T. M.; Zuercher, W. J.
10.1101/094631 — pharmacology and toxicology — Posted on 2017-03-02
1074 Genetic Analysis of a Metazoan Pathway using Transcriptomic Phenotypes
Angeles Albores, D.; Puckett Robinson, C.; Williams, B. A.; Wold, B. J.; Sternberg, P. W.
10.1101/112920 — genetics — Posted on 2017-03-02
1075 microCT-Based Skeletal Phenomics in Zebrafish Reveals Virtues of Deep Phenotyping at the Whole-Organism Scale
Hur, M.; Gistelinck, C. A.; Huber, P.; Lee, J.; Thompson, M. H.; Monstad-Rios, A. T.; Watson, C. J.; McMenamin, S. K.; Willaert, A.; Parichy, D. M.; Coucke, P.; Kwon, R. Y.
10.1101/105569 — genetics — Posted on 2017-03-02
1078 Simple rules for an efficient use of Geographic Information Systems in molecular ecology
Leempoel, K.; Duruz, S.; Rochat, E.; Widmer, I.; Orozco-terWengel, P.; Joost, S.
10.1101/113225 — ecology — Posted on 2017-03-02
1081 Development of a high-density, 2M SNP genotyping array and 670k SNP imputation array for the domestic horse
Schaefer, R. J.; Schubert, M.; Bailey, E.; Bannasch, D. L.; Barrey, E.; Kahila Bar-Gal, G.; Brem, G.; Brooks, S. A.; Distl, O.; Fries, R.; Finno, C. J.; Gerber, V.; Haase, B.; Jagannathan, V.; Kalbfleisch, T.; Leeb, T.; Lindgren, G.; Susana Lopes, M.; Mach, N.; da Camara Machado, A.; MacLeod, J. N.; McCoy, A.; Metzger, J.; Penedo, C.; Polani, S.; Rieder, S.; Tammen, I.; Tetens, J.; Thaller, G.; Verini-Supplizi, A.; Wade, C. M.; Wallner, B.; Orlando, L.; Mickelson, J. R.; McCue, M. E.
10.1101/112979 — genomics — Posted on 2017-03-02
1082 Human-specific methylated regions are enriched in schizophrenia
Banerjee, N.; Polushina, T.; Bettella, F.; Giddaluru, S.; Steen, V. M.; Andreassen, O. A.; Hellard, S. L.
10.1101/113175 — genetics — Posted on 2017-03-02
1085 A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress
McMurchy, A. N.; Stempor, P.; Gaarenstroom, T.; Wysolmerski, B.; Dong, Y.; Aussianikava, D.; Appert, A.; Huang, N.; Kolasinska-Zweirz, P.; Sapetschnig, A.; Miska, E.; Ahringer, J.
10.1101/112847 — genomics — Posted on 2017-03-02
1086 Extensive farming in Estonia started through a sex-biased migration from the Steppe
Saag, L.; Varul, L.; Scheib, C. L.; Stenderup, J.; Allentoft, M. E.; Saag, L.; Pagani, L.; Reidla, M.; Tambets, K.; Metspalu, E.; Kriiska, A.; Willerslev, E.; Kivisild, T.; Metspalu, M.
10.1101/112714 — evolutionary biology — Posted on 2017-03-02
1087 Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations
Counago, R. M.; Allerston, C. K.; Savitsky, P.; Azevedo, H.; Godoi, P. H.; Wells, C. I.; Mascarello, A.; de Souza Gama, F. H.; Massirer, K. B.; Zuercher, W. J.; Guimaraes, C. R. W.; Gileadi, O.
10.1101/112763 — biochemistry — Posted on 2017-03-02
1088 The stoichiometric signature of Rhodopsin-family G protein coupled receptors
Felce, J. H.; Latty, S. L.; Knox, R. G.; Mattick, S. R.; Lui, Y.; Lee, S. F.; Klenerman, D.; Davis, S. J.
10.1101/112466 — biochemistry — Posted on 2017-03-02
1091 Bacterial Microtubules Exhibit Polarized Growth, Mixed-Polarity Bundling, and Destabilization by GTP Hydrolysis
Diaz Celis, C. D.; Risca, V. I.; Hurtado, F.; Polka, J. K.; Hansen, S. D.; Maturana, D.; Lagos, R.; Mullins, R. D.; Monasterio, O.
10.1101/112987 — microbiology — Posted on 2017-03-02
1092 The translational landscape of Zika virus during infection of mammalian and insect cells
Irigoyen, N.; Dinan, A. M.; Meredith, L. W.; Goodfellow, I. G.; Brierley, I.; Firth, A. E.
10.1101/112904 — microbiology — Posted on 2017-03-02
1093 Gene fusion between CDKN1A and RAB44 caused by exon skipping like mechanism due to disruption of a splice site
Sun, H.; Wu, J.; Zhu, C.; Aiyar, R.; Jakob, P.; Mueller, W.; Wei, W.; Steinmetz, L.
10.1101/111856 — genetics — Posted on 2017-03-02
1095 Genetic Analysis of a Metazoan Pathway using Transcriptomic Phenotypes
Angeles Albores, D.; Puckett Robinson, C.; Williams, B. A.; Sternberg, P. W.
10.1101/112920 — genetics — Posted on 2017-03-02
1098 Stochastic model of contact inhibition and the proliferation of melanoma in situ
Morais, M. C. C.; Stuhl, I.; Sabino, A. U.; Lautenschlager, W. W.; Queiroga, A. S.; Tortelli, T. C.; Chammas, R.; Suhov, Y.; Ramos, A. F.
10.1101/110007 — cancer biology — Posted on 2017-03-02
1099 Heterogeneous chromatin mobility derived from chromatin states is a determinant of genome organisation in S. cerevisiae
Sewitz, S. A.; Fahmi, Z.; Aljebali, L.; Bancroft, J.; Brustolini, O. J. B.; Saad, H.; Goiffon, I.; Varnai, C.; Wingett, S.; Wong, H.; Javierre, B.-M.; Schoenfelder, S.; Andrews, S.; Oliver, S. G.; Fraser, P.; Bystricky, K.; Lipkow, K.
10.1101/106344 — systems biology — Posted on 2017-03-02
1104 Large-scale simultaneous measurement of epitopes and transcriptomes in single cells.
Stoeckius, M.; Hafemeister, C.; Stephenson, W.; Houck-Loomis, B.; Swerdlow, H.; Satija, R.; Smibert, P.
10.1101/113068 — genomics — Posted on 2017-03-02
1106 Genome-wide association study of asthma in individuals of African ancestry reveals novel asthma susceptibility loci
Daya, M.; Rafaels, N.; Chavan, S.; Johnston, H. R.; Shetty, A.; Gignoux, C. R.; Boorgula, M. P.; Campbell, M.; Maul, P.; Maul, T.; Vergara, C.; Levin, A. M.; Wojcik, G.; Torgerson, D. G.; Ortega, V. E.; Doumatey, A.; Araujo, M. I.; Avila, P. C.; Bleecker, E.; Bustamante, C.; Caraballo, L.; Dunston, G. M.; Faruque, M. U.; Ferguson, T.; Figueiredo, C.; Ford, J. G.; Gourraud, P.-A.; Hansel, N. N.; Hernandez, R. D.; Herrera-Paz, E. F.; Kenny, E. E.; Knight-Madden, J.; Kumar, R.; Lange, L. A.; Lange, E. M.; Lizee, A.; Mayorga, A.; Meyers, D.; Nicolae, D. L.; O'Connor, T. D.; Oliveira, R. R.; Olopad
10.1101/112953 — bioinformatics — Posted on 2017-03-02
1108 A genome-wide interactome of DNA-associated proteins in the human liver
Ramaker, R. C.; Savic, D.; Hardigan, A. A.; Newberry, K.; Cooper, G. M.; Myers, R. M.; Cooper, S. J.
10.1101/111385 — genomics — Posted on 2017-03-01
1109 Evaluating the clinical validity of gene-disease associations: an evidence-based framework developed by the Clinical Genome Resource
Strande, N. T.; Riggs, E. R.; Buchanan, A. H.; Ceyhan-Birsoy, O.; DiStefano, M. T.; Dwight, S. S.; Goldstein, J. L.; Ghosh, R.; Seifert, B. A.; Sneddon, T. P.; Wright, M. W.; Milko, L. V.; Giovanni, M. A.; Murray, M. F.; O'Daniel, J. M.; Ramos, E. M.; Santani, A. B.; Scott, A. F.; Cherry, J. M.; Plon, S. E.; Rehm, H. L.; Martin, C. L.; Berg, J. S.
10.1101/111039 — genetics — Posted on 2017-03-01
1110 Conflicting evolutionary histories of the mitochondrial and nuclear genomes in New World Myotis
Platt, R. N.; Faircloth, B. C.; Sullivan, K. A. M.; Kieran, T.; Glenn, T. C.; Vandewege, M. W.; Lee, T. E.; Baker, R. J.; Stevens, R. D.; Ray, D. A.
10.1101/112581 — evolutionary biology — Posted on 2017-03-01
1111 Logistic proliferation of cells in scratch assays is delayed
Jin, W.; Shah, E. T.; Penington, C. J.; McCue, S. W.; Maini, P. K.; Simpson, M. J.
10.1101/077388 — biophysics — Posted on 2017-03-01
1112 Large-scale interpretation of chemical-genetic interaction profiles using a genetic interaction network
Simpkins, S. W.; Nelson, J.; Deshpande, R.; Li, S. C.; Piotrowski, J. S.; Wilson, E. H.; Gebre, A. A.; Okamoto, R.; Ohya, Y.; Osada, H.; Yoshida, M.; Boone, C.; Myers, C. L.
10.1101/111252 — systems biology — Posted on 2017-03-01
1114 Hierarchical cortical transcriptome disorganization in autism
Lombardo, M. V.; Courchesne, E.; Lewis, N. E.; Pramparo, T.
10.1101/042937 — genomics — Posted on 2017-03-01
1120 Evolution of ribosomal internal transcribed spacers in Deuterostomia
Dyomin, A.; Volodkina, V.; Koshel, E.; Galkina, S.; Saifitdinova, A.; Gaginskaya, E.
10.1101/112797 — molecular biology — Posted on 2017-03-01
1122 Population dynamics of immune repertoires
Desponds, J.; Mayer, A.; Mora, T.; Walczak, A. M.
10.1101/112755 — immunology — Posted on 2017-03-01
1123 Discovery and reporting of clinically-relevant germline variants in advanced cancer patients assessed using whole-exome sequencing
Zhang, T.; Romanel, A.; Eng, K. W.; Rennert, H.; Tan, A. Y.; Xue, Y.; Cyrta, J.; Mosquera, J. M.; Sboner, A.; Iossifov, I.; Lipkin, S. M.; Xiang, J.; Feng, X.; Nelson, P.; Beltran, H.; Pritchard, C. C.; Rubin, M. A.; Demichelis, F.; Elemento, O.
10.1101/112672 — genomics — Posted on 2017-03-01
1129 Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus
Yoshida, Y.; Koutsovoulos, G.; Laetsch, D. R.; Stevens, L.; Kumar, S.; Horikawa, D. D.; Ishino, K.; Komine, S.; Kunieda, T.; Tomita, M.; Blaxter, M.; Arakawa, K.
10.1101/112664 — genomics — Posted on 2017-03-01
1130 Systematic identification of pleiotropic genes from genetic interactions
Koch, E. N.; Costanzo, M.; Deshpande, R.; Andrews, B.; Boone, C.; Myers, C. L.
10.1101/112326 — genomics — Posted on 2017-03-01
1132 On the distribution and function of synaptic clusters
Caze, R. D.; Foust, A. J.; Clopath, C.; Schultz, S. R.
10.1101/029330 — neuroscience — Posted on 2017-03-01
1135 Recent Regulatory Changes Shaped Human Facial and Vocal Anatomy
Gokhman, D.; Agranat-Tamir, L.; Housman, G.; Nissim-Rafinia, M.; Nieves-Colon, M.; Gu, H.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Quillen, E. E.; Meissner, A.; Stone, A. C.; Pusey, A. E.; Mjungu, D.; Kandel, L.; Liebergall, M.; Prada, M. E.; Vidal, J. M.; Krause, J.; Yakir, B.; Paabo, S.; Reich, D.; Lalueza-Fox, C.; Marques-Bonet, T.; Meshorer, E.; Carmel, L.
10.1101/106955 — genomics — Posted on 2017-03-01
1136 Repli-seq: genome-wide analysis of replication timing by next-generation sequencing
Marchal, C.; Sasaki, T.; Vera, D.; Wilson, K.; Sima, J.; Rivera-Mulia, J.-C.; Trevilla Garcia, C.; Nogues, C.; Nafie, E.; Gilbert, D. M.
10.1101/104653 — genomics — Posted on 2017-03-01
1137 microCT-Based Skeletal Phenomics in Zebrafish Reveals Virtues of Deep Phenotyping at the Whole-Organism Scale
Hur, M.; Gistelinck, C. A.; Huber, P.; Lee, J.; Thompson, M. H.; Monstad-Rios, A. T.; Watson, C. J.; McMenamin, S. K.; Willaert, A.; Parichy, D. M.; Coucke, P.; Kwon, R. Y.
10.1101/105569 — genetics — Posted on 2017-03-01
1140 Multiplexed confocal and super-resolution fluorescence imaging of cytoskeletal and neuronal synapse proteins
Guo, S.-M.; Veneziano, R.; Gordonov, S.; Li, L.; Park, D.; Kulesa, A. B.; Blainey, P. C.; Cottrell, J. R.; Boyden, E. S.; Bathe, M.
10.1101/111625 — bioengineering — Posted on 2017-03-01